Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001528-TA|BGIBMGA001528-PA|IPR000980|SH2 motif
(665 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA... 338 2e-91
UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA... 328 2e-88
UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ... 256 1e-66
UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; ... 250 7e-65
UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gamb... 201 6e-50
UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146... 177 8e-43
UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h... 125 3e-27
UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am... 124 6e-27
UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B... 124 1e-26
UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;... 120 2e-25
UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep: Zgc... 116 3e-24
UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;... 112 3e-23
UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D... 110 1e-22
UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E... 103 2e-20
UniRef50_UPI00006A214E Cluster: SH2 domain-containing adapter pr... 100 1e-19
UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homolo... 99 3e-19
UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome sh... 89 3e-16
UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma j... 83 2e-14
UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome sh... 73 2e-11
UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:... 64 1e-08
UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ... 63 3e-08
UniRef50_Q08BW5 Cluster: Zgc:154062; n=1; Danio rerio|Rep: Zgc:1... 60 1e-07
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 60 1e-07
UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3; ... 60 2e-07
UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase... 59 3e-07
UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H... 59 4e-07
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 58 6e-07
UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E... 58 6e-07
UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ... 58 6e-07
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 58 6e-07
UniRef50_Q6P8E0 Cluster: Suppressor of cytokine signaling 3; n=2... 58 8e-07
UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Re... 58 8e-07
UniRef50_Q4RX78 Cluster: Chromosome 11 SCAF14979, whole genome s... 58 1e-06
UniRef50_Q06AL4 Cluster: Suppressor of cytokine signaling 1; n=5... 58 1e-06
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 58 1e-06
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 58 1e-06
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 57 1e-06
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 57 2e-06
UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve... 57 2e-06
UniRef50_UPI0000F2066F Cluster: PREDICTED: similar to Src homolo... 56 2e-06
UniRef50_Q4S861 Cluster: Chromosome 5 SCAF14709, whole genome sh... 56 2e-06
UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1; ... 56 2e-06
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 56 2e-06
UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; ... 56 3e-06
UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth fac... 56 4e-06
UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh... 56 4e-06
UniRef50_Q9NSE2 Cluster: Cytokine-inducible SH2-containing prote... 56 4e-06
UniRef50_UPI0000E49F60 Cluster: PREDICTED: hypothetical protein;... 55 5e-06
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 55 5e-06
UniRef50_Q7YWN4 Cluster: Putative uncharacterized protein; n=2; ... 55 7e-06
UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j... 55 7e-06
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 55 7e-06
UniRef50_Q4H2S5 Cluster: Suppressor of cytokine signaling; n=1; ... 54 9e-06
UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;... 54 2e-05
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 54 2e-05
UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome s... 54 2e-05
UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase... 53 3e-05
UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb... 53 3e-05
UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo... 53 3e-05
UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; A... 53 3e-05
UniRef50_UPI000058773D Cluster: PREDICTED: hypothetical protein;... 52 4e-05
UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph... 52 4e-05
UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le... 52 4e-05
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 52 4e-05
UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;... 52 4e-05
UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;... 52 5e-05
UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=... 52 7e-05
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 52 7e-05
UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain... 51 9e-05
UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot... 51 9e-05
UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot... 51 9e-05
UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin... 51 9e-05
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 51 1e-04
UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;... 50 2e-04
UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;... 50 2e-04
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 50 2e-04
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 50 2e-04
UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;... 50 2e-04
UniRef50_UPI0000F1F0F1 Cluster: PREDICTED: hypothetical protein;... 50 2e-04
UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad... 50 2e-04
UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome s... 50 2e-04
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 50 2e-04
UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|... 50 2e-04
UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=2... 50 2e-04
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 50 2e-04
UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;... 50 3e-04
UniRef50_Q6DEF9 Cluster: Zgc:91868; n=1; Danio rerio|Rep: Zgc:91... 50 3e-04
UniRef50_Q380D8 Cluster: ENSANGP00000027059; n=2; Culicidae|Rep:... 50 3e-04
UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;... 50 3e-04
UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-... 50 3e-04
UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;... 49 3e-04
UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate pho... 49 3e-04
UniRef50_O15524 Cluster: Suppressor of cytokine signaling 1; n=1... 49 3e-04
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 49 3e-04
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 49 5e-04
UniRef50_UPI0000DB7263 Cluster: PREDICTED: similar to Suppressor... 49 5e-04
UniRef50_Q4RXL6 Cluster: Chromosome 11 SCAF14979, whole genome s... 49 5e-04
UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory s... 49 5e-04
UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;... 49 5e-04
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 49 5e-04
UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty... 48 6e-04
UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol... 48 6e-04
UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s... 48 6e-04
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 48 6e-04
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 48 6e-04
UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to ENSANGP000... 48 8e-04
UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain... 48 8e-04
UniRef50_UPI0000D56C32 Cluster: PREDICTED: similar to Suppressor... 48 8e-04
UniRef50_O14508 Cluster: Suppressor of cytokine signaling 2; n=2... 48 8e-04
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 48 8e-04
UniRef50_UPI0000D5590C Cluster: PREDICTED: similar to Suppressor... 48 0.001
UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal tra... 47 0.001
UniRef50_Q4H2S4 Cluster: Suppressor of cytokine signaling; n=1; ... 47 0.001
UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to Src-like-a... 47 0.002
UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ... 47 0.002
UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ... 47 0.002
UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept... 47 0.002
UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; ... 46 0.002
UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n... 46 0.002
UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n... 46 0.002
UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleos... 46 0.002
UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep: Zgc:... 46 0.002
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 46 0.002
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 46 0.002
UniRef50_UPI0000F1D282 Cluster: PREDICTED: hypothetical protein;... 46 0.003
UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus nor... 46 0.003
UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain... 46 0.004
UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5; Euteleostomi|... 46 0.004
UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome sh... 46 0.004
UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep: CG3240... 46 0.004
UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 p... 46 0.004
UniRef50_Q45FX5 Cluster: Protein vav-1; n=4; Caenorhabditis|Rep:... 46 0.004
UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 46 0.004
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 46 0.004
UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept... 46 0.004
UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei... 45 0.006
UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65... 45 0.006
UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio re... 45 0.006
UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted... 45 0.006
UniRef50_Q16U30 Cluster: Putative uncharacterized protein; n=1; ... 45 0.006
UniRef50_A7SGW3 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.006
UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R... 45 0.006
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 45 0.006
UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;... 45 0.007
UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol... 45 0.007
UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|R... 45 0.007
UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E... 45 0.007
UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb... 44 0.010
UniRef50_Q90X67 Cluster: Suppressor of cytokine signaling 3; n=1... 44 0.010
UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 44 0.010
UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulator... 44 0.010
UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adapto... 44 0.013
UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome s... 44 0.013
UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whol... 44 0.013
UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s... 44 0.013
UniRef50_Q9W4A9 Cluster: CG3208-PA, isoform A; n=5; Diptera|Rep:... 44 0.013
UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium discoi... 44 0.013
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 44 0.013
UniRef50_O14543 Cluster: Suppressor of cytokine signaling 3; n=2... 44 0.013
UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21; Euteleostomi|... 44 0.013
UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ... 44 0.013
UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep: P4... 44 0.013
UniRef50_UPI0000D559E9 Cluster: PREDICTED: similar to CG8146-PA;... 44 0.017
UniRef50_UPI00015A6A53 Cluster: hypothetical protein LOC406311; ... 44 0.017
UniRef50_Q6PBV3 Cluster: Zgc:73230; n=2; Danio rerio|Rep: Zgc:73... 44 0.017
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 44 0.017
UniRef50_Q9VX18 Cluster: CG8146-PA; n=1; Drosophila melanogaster... 44 0.017
UniRef50_Q5BXE5 Cluster: SJCHGC04002 protein; n=1; Schistosoma j... 44 0.017
UniRef50_Q29G65 Cluster: GA20849-PA; n=1; Drosophila pseudoobscu... 44 0.017
UniRef50_UPI0000F1F169 Cluster: PREDICTED: hypothetical protein;... 43 0.023
UniRef50_UPI0000D555ED Cluster: PREDICTED: similar to CG32406-PA... 43 0.023
UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen resi... 43 0.023
UniRef50_UPI0000503A18 Cluster: UPI0000503A18 related cluster; n... 43 0.023
UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut... 43 0.023
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 43 0.023
UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty... 43 0.023
UniRef50_Q63HR2 Cluster: Tensin-like C1 domain-containing phosph... 43 0.023
UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Re... 43 0.023
UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing pro... 43 0.023
UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil... 43 0.023
UniRef50_UPI00015B6424 Cluster: PREDICTED: similar to CG8146-PA;... 43 0.030
UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-relate... 43 0.030
UniRef50_UPI0000DB7BD4 Cluster: PREDICTED: similar to Suppressor... 43 0.030
UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,... 43 0.030
UniRef50_UPI00006A0ADF Cluster: Tensin-1.; n=5; Xenopus tropical... 43 0.030
UniRef50_UPI000069FBD8 Cluster: tensin like C1 domain containing... 43 0.030
UniRef50_UPI000069FBD7 Cluster: tensin like C1 domain containing... 43 0.030
UniRef50_UPI000069FBD6 Cluster: tensin like C1 domain containing... 43 0.030
UniRef50_UPI000069EEDB Cluster: UPI000069EEDB related cluster; n... 43 0.030
UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C... 43 0.030
UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lym... 43 0.030
UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho... 43 0.030
UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p... 43 0.030
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 43 0.030
UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulator... 43 0.030
UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.030
UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:... 43 0.030
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 43 0.030
UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4; ... 43 0.030
UniRef50_UPI0000DB734C Cluster: PREDICTED: similar to Suppressor... 42 0.040
UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3 (Lymphocy... 42 0.040
UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.040
UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.040
UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|... 42 0.040
UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;... 42 0.040
UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15; Tetrapoda... 42 0.040
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 42 0.040
UniRef50_UPI0000D5672D Cluster: PREDICTED: similar to CG3208-PA,... 42 0.053
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 42 0.053
UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid... 42 0.053
UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome sh... 42 0.053
UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src... 42 0.053
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 42 0.053
UniRef50_Q5C0L2 Cluster: SJCHGC05893 protein; n=1; Schistosoma j... 42 0.053
UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7; Tetrapoda|... 42 0.053
UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep: Zgc... 42 0.070
UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb... 42 0.070
UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p - ... 42 0.070
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 42 0.070
UniRef50_A7RUJ8 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.070
UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7; Endopterygot... 42 0.070
UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C pro... 41 0.092
UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to phosphoino... 41 0.092
UniRef50_UPI0000D9E331 Cluster: PREDICTED: similar to Suppressor... 41 0.092
UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no... 41 0.092
UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:... 41 0.092
UniRef50_O14512 Cluster: Suppressor of cytokine signaling 7; n=1... 41 0.092
UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34; Eutel... 41 0.092
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 41 0.092
UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarc... 41 0.12
UniRef50_Q4SR72 Cluster: Chromosome 11 SCAF14528, whole genome s... 41 0.12
UniRef50_Q8WP81 Cluster: Putative uncharacterized protein; n=2; ... 41 0.12
UniRef50_Q7Q5B6 Cluster: ENSANGP00000004338; n=1; Anopheles gamb... 41 0.12
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 41 0.12
UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein;... 40 0.16
UniRef50_UPI0000F1ED8A Cluster: PREDICTED: similar to TNS1 prote... 40 0.16
UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,... 40 0.16
UniRef50_Q4SM94 Cluster: Chromosome 3 SCAF14553, whole genome sh... 40 0.16
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 40 0.16
UniRef50_Q4H2S6 Cluster: Suppressor of cytokine signaling; n=1; ... 40 0.16
UniRef50_Q04205 Cluster: Tensin; n=12; Euteleostomi|Rep: Tensin ... 40 0.16
UniRef50_Q9HBL0 Cluster: Tensin-1; n=44; Eumetazoa|Rep: Tensin-1... 40 0.16
UniRef50_O75159 Cluster: Suppressor of cytokine signaling 5; n=3... 40 0.16
UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing pro... 40 0.16
UniRef50_UPI00015B5375 Cluster: PREDICTED: similar to tensin; n=... 40 0.21
UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome sh... 40 0.21
UniRef50_Q8INY1 Cluster: CG15154-PB, isoform B; n=6; Coelomata|R... 40 0.21
UniRef50_Q4JSB7 Cluster: Tensin; n=3; Culicidae|Rep: Tensin - An... 40 0.21
UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;... 40 0.21
UniRef50_A7SKN8 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 40 0.21
UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ... 40 0.21
UniRef50_Q91ZA6 Cluster: Suppressor of cytokine signaling 4; n=1... 40 0.21
UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB... 40 0.28
UniRef50_UPI00005A2FA4 Cluster: PREDICTED: similar to tensin-lik... 40 0.28
UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|R... 40 0.28
UniRef50_Q4SM05 Cluster: Chromosome 13 SCAF14555, whole genome s... 40 0.28
UniRef50_Q54U31 Cluster: SH2 domain-containing protein; n=1; Dic... 40 0.28
UniRef50_Q29LD7 Cluster: GA13535-PA; n=1; Drosophila pseudoobscu... 40 0.28
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.28
UniRef50_Q68CZ2 Cluster: Tensin-3; n=33; Euteleostomi|Rep: Tensi... 40 0.28
UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16; Euteleost... 40 0.28
UniRef50_UPI0000D577DA Cluster: PREDICTED: similar to CG7893-PA,... 39 0.37
UniRef50_UPI0000D56397 Cluster: PREDICTED: similar to Tensin-1; ... 39 0.37
UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-contain... 39 0.37
UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-... 39 0.37
UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; ... 39 0.37
UniRef50_Q5BYR6 Cluster: SJCHGC04559 protein; n=1; Schistosoma j... 39 0.37
UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 39 0.37
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 39 0.37
UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling ... 39 0.49
UniRef50_UPI0000DB7727 Cluster: PREDICTED: similar to Tensin-1; ... 39 0.49
UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n... 39 0.49
UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound pro... 39 0.49
UniRef50_UPI0000ECA015 Cluster: Suppressor of cytokine signaling... 39 0.49
UniRef50_Q5U3P8 Cluster: Zgc:101809; n=5; Danio rerio|Rep: Zgc:1... 39 0.49
UniRef50_Q4T639 Cluster: Chromosome undetermined SCAF8942, whole... 39 0.49
UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome s... 39 0.49
UniRef50_Q95ZL4 Cluster: Temporarily assigned gene name protein ... 39 0.49
UniRef50_Q54Y55 Cluster: SH2 domain-containing protein; n=1; Dic... 39 0.49
UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) ... 39 0.49
UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing) ... 39 0.49
UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 39 0.49
UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetra... 39 0.49
UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance ... 39 0.49
UniRef50_UPI0000F1E232 Cluster: PREDICTED: hypothetical protein;... 38 0.65
UniRef50_UPI0000E48AB6 Cluster: PREDICTED: similar to B-cell lin... 38 0.65
UniRef50_UPI0000DB7AEC Cluster: PREDICTED: similar to Suppressor... 38 0.65
UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3 (Lymphocy... 38 0.65
UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocy... 38 0.65
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 38 0.65
UniRef50_Q4RVK7 Cluster: Chromosome 15 SCAF14992, whole genome s... 38 0.65
UniRef50_Q9N597 Cluster: Phosphoinositide kinase adapter subunit... 38 0.65
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 38 0.65
UniRef50_UPI00015B50BA Cluster: PREDICTED: similar to suppressor... 38 0.86
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 38 0.86
UniRef50_UPI0000F1E3ED Cluster: PREDICTED: similar to cardiac mu... 38 0.86
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 38 0.86
UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain... 38 0.86
UniRef50_UPI0000D55C47 Cluster: PREDICTED: similar to CG33175-PG... 38 0.86
UniRef50_UPI0000ECCD76 Cluster: tensin 3; n=1; Gallus gallus|Rep... 38 0.86
UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whol... 38 0.86
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 38 0.86
UniRef50_Q4SRP3 Cluster: Chromosome undetermined SCAF14505, whol... 38 0.86
UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome s... 38 0.86
UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep: Zgc... 38 0.86
UniRef50_Q9Y1Y4 Cluster: Tyrosine-protein kinase; n=1; Ephydatia... 38 0.86
UniRef50_Q5BXM9 Cluster: SJCHGC06039 protein; n=1; Schistosoma j... 38 0.86
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 38 0.86
UniRef50_P46639 Cluster: Homeobox protein knotted-1-like 1; n=29... 38 0.86
UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol p... 38 1.1
UniRef50_UPI0000F2115F Cluster: PREDICTED: similar to tensin lik... 38 1.1
UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-pro... 38 1.1
UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome sh... 38 1.1
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 38 1.1
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 38 1.1
UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella ve... 38 1.1
UniRef50_Q85476 Cluster: (recovered insertion mutant of B77) src... 37 1.5
UniRef50_Q1KL02 Cluster: Chimerin 2; n=3; Tetraodontidae|Rep: Ch... 37 1.5
UniRef50_Q9VHC3 Cluster: CG9379-PA; n=2; Drosophila melanogaster... 37 1.5
UniRef50_Q9NHC3 Cluster: Cell-corpse engulfment protein CED-2; n... 37 1.5
UniRef50_Q7PQV9 Cluster: ENSANGP00000003034; n=1; Anopheles gamb... 37 1.5
UniRef50_A7T8K3 Cluster: Predicted protein; n=1; Nematostella ve... 37 1.5
UniRef50_A7RU23 Cluster: Predicted protein; n=1; Nematostella ve... 37 1.5
UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella ve... 37 1.5
UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel... 37 1.5
UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 ... 37 2.0
UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound pro... 37 2.0
UniRef50_Q4SIP6 Cluster: Chromosome 21 SCAF14577, whole genome s... 37 2.0
UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 37 2.0
UniRef50_Q86F73 Cluster: Clone ZZD1053 mRNA sequence; n=1; Schis... 37 2.0
UniRef50_Q5BW49 Cluster: SJCHGC04880 protein; n=1; Schistosoma j... 37 2.0
UniRef50_UPI0000EC9DFE Cluster: SH2 domain-containing protein 2A... 36 2.6
UniRef50_Q86B13 Cluster: Similar to Dictyostelium discoideum (Sl... 36 2.6
UniRef50_Q17M69 Cluster: Rab gdp/gtp exchange factor; n=1; Aedes... 36 2.6
UniRef50_A7RGQ1 Cluster: Predicted protein; n=1; Nematostella ve... 36 2.6
UniRef50_Q8IZW8 Cluster: Tensin-4 precursor; n=17; Eutheria|Rep:... 36 2.6
UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing pro... 36 2.6
UniRef50_UPI0000E818A6 Cluster: PREDICTED: similar to Myosin-VII... 36 3.5
UniRef50_Q03I02 Cluster: Subtilisin-like serine protease; n=1; P... 36 3.5
UniRef50_Q621U0 Cluster: Putative uncharacterized protein CBG023... 36 3.5
UniRef50_Q54ZG8 Cluster: Putative uncharacterized protein; n=2; ... 36 3.5
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E... 36 3.5
UniRef50_Q6ZV89 Cluster: SH2 domain-containing protein 5; n=17; ... 36 3.5
UniRef50_Q9NZW4 Cluster: Dentin sialophosphoprotein precursor [C... 36 3.5
UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adapt... 36 4.6
UniRef50_UPI00006CD8C0 Cluster: hypothetical protein TTHERM_0052... 36 4.6
UniRef50_Q4SZG7 Cluster: Chromosome 18 SCAF11624, whole genome s... 36 4.6
UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome sh... 36 4.6
UniRef50_Q54B22 Cluster: Putative uncharacterized protein; n=1; ... 36 4.6
UniRef50_A7RRM1 Cluster: Predicted protein; n=1; Nematostella ve... 36 4.6
UniRef50_A4VB01 Cluster: Putative uncharacterized protein; n=1; ... 36 4.6
UniRef50_UPI0000E48882 Cluster: PREDICTED: similar to tensin hom... 35 6.1
UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad... 35 6.1
UniRef50_Q9GYK6 Cluster: Putative uncharacterized protein; n=4; ... 35 6.1
UniRef50_Q8IS10 Cluster: Nucleotide exchange factor RasGEF P; n=... 35 6.1
UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gamb... 35 6.1
UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; ... 35 6.1
UniRef50_A7SPF7 Cluster: Predicted protein; n=1; Nematostella ve... 35 6.1
UniRef50_A7RFH8 Cluster: Predicted protein; n=1; Nematostella ve... 35 6.1
UniRef50_Q2UK86 Cluster: Predicted protein; n=2; Aspergillus|Rep... 35 6.1
UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetra... 35 6.1
UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19;... 35 6.1
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 35 6.1
UniRef50_Q13322-2 Cluster: Isoform 1 of Q13322 ; n=5; Homo/Pan/G... 35 8.0
UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1... 35 8.0
UniRef50_A1S7M2 Cluster: TPR domain protein precursor; n=1; Shew... 35 8.0
UniRef50_Q9VRR9 Cluster: CG10479-PA; n=2; Sophophora|Rep: CG1047... 35 8.0
UniRef50_Q9VBB3 Cluster: CG5491-PA; n=2; Sophophora|Rep: CG5491-... 35 8.0
UniRef50_Q965N4 Cluster: Putative uncharacterized protein; n=3; ... 35 8.0
UniRef50_Q869U4 Cluster: Similar to Arabidopsis thaliana (Mouse-... 35 8.0
UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia roretzi... 35 8.0
UniRef50_O01325 Cluster: Putative uncharacterized protein; n=2; ... 35 8.0
UniRef50_A2EBQ3 Cluster: Retinitis pigmentosa GTPase regulator-l... 35 8.0
UniRef50_Q0UFV6 Cluster: Putative uncharacterized protein; n=1; ... 35 8.0
UniRef50_Q13322 Cluster: Growth factor receptor-bound protein 10... 35 8.0
>UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA
isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG11146-PA isoform 2 - Apis mellifera
Length = 1122
Score = 338 bits (832), Expect = 2e-91
Identities = 261/747 (34%), Positives = 346/747 (46%), Gaps = 100/747 (13%)
Query: 4 RQIYETAFDCKIARSXXXXXXXXRVSNHPAL---LQAEERKIISSASSAFEAVERSEPDF 60
R +YETAFDCK+ RS RV+NHP L +++ +S SS+ + ++ +
Sbjct: 391 RHLYETAFDCKVNRSDDDLDDLDRVTNHPVLHSQIRSSSAIPVSRTSSSTDTSKQQQQQQ 450
Query: 61 ----------KGRRKVTMKTDSVRRSKIPTIRQKRENEN-NACALSEELEKVHIEGEERV 109
K RRKV + S++ +Q+++ ++ N LS+++E + I +
Sbjct: 451 APYAGQSHSNKDRRKVVLLRPKPIPSRLQQQQQQQQQQSDNISTLSQDIESLQINSSDEK 510
Query: 110 ASNSQLPLRGYXXXXXXXXXXXXKFQQKDGSAMNSIKSAPNLPQAQPAHPRLKDLRLPVK 169
+ +LP RGY KF + +I+S PNLP +QP HPRLKDLRLPVK
Sbjct: 511 TGSPRLPARGYTPSPPSTAPLPAKFHGNRDHLLLNIRSTPNLP-SQPDHPRLKDLRLPVK 569
Query: 170 S-LRARDTPTSSDAS-MDVKGSVST----------------ELDIXXXXXXXXXXXXXXX 211
S LRA+D+P SS+ S +++K + EL +
Sbjct: 570 SSLRAKDSPQSSEGSILEIKSRPKSFAQETVESSQGRRFDKELILEFKGRPREDRQRPRS 629
Query: 212 XXAQSKDGIFLEIKGRP-TSDSDTPEMNRYTGPKGVGPIMEFKGRPGVIRPRRKYXXXXX 270
+SK +E KGRP ++SD R G ++EFK R RP
Sbjct: 630 LIRESKP--IMEFKGRPHEAESDLLRPRRDVG------LLEFKLRTSRRRPGYSSTESMA 681
Query: 271 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPFSKSHHMQLGFGHH 330
GF H
Sbjct: 682 TSSSGGSMESLRSSTSEGNRSTSSSESRHSTSLSSHSSDSGGTNCYHHHQQPSMTGFLTH 741
Query: 331 HPAKLNILSPISDKSSQEPASETSDNNKNNNSQKVSPEEG-----------------DTG 373
H KL+ILSPISDKSSQEPASETSDNN+NNNSQK SPEE TG
Sbjct: 742 HANKLHILSPISDKSSQEPASETSDNNRNNNSQKASPEENVTTENNVTATNNVTNTNTTG 801
Query: 374 NATIQTAVEIIAKPKXXXXXXXXXXXXTFRHSATGDAEIQGSDSGISIHSREGVDSRN-A 432
N T+ + K + S++GDAEIQGSDSGISI SR G+ +
Sbjct: 802 NTNSVTSPMDTSFKKRRTPQNKNLINLALQSSSSGDAEIQGSDSGISIESRAGIKCKPFG 861
Query: 433 FINFKNSNTGEERKNDDVDLSDLPFDMPKL-----------XXXXXXXXXDLRTLPFDMP 481
F K +++ +LSDLPFDMPKL DLR LPFDMP
Sbjct: 862 FHLLKPQLDNINLVDNEPELSDLPFDMPKLRRRRLLMQQDATTSGSATSVDLRDLPFDMP 921
Query: 482 KLRRKLRGQSLQLNDEFGGGISNASSSQSVEDLNQGNK------LKSSLKLNFDXXXXXX 535
KL+R+LR +Q + G S ASSS SV D + + + ++ LN D
Sbjct: 922 KLKRRLR--CMQSTESSG---SQASSSLSVRDGRKVSYCLQCILFRRNMTLNLDAGNGTG 976
Query: 536 X---------------XKGLHLNLGPIAPPRDLVDATLPLDRQGWYHGTLARVEAESLLR 580
GL L + DLVD LPL+RQGWYHG++ R+EAE++LR
Sbjct: 977 NGGNSGQLPPKKPGGLSLGLPLEINTARGSADLVDVGLPLERQGWYHGSITRIEAEAVLR 1036
Query: 581 DADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE--GYTLGGASTAFPSVPALMR 638
EG++LVRNSES K DYSLSLKS RGFMHMRI + E Y LG S F S+P ++R
Sbjct: 1037 LLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEELNAYILGQFSKPFDSIPEMVR 1096
Query: 639 HYVTAQRLPVRGAEHMALSTPLPAVLL 665
H+ + RLP+RGAEHM L P+ A LL
Sbjct: 1097 HF-SVNRLPIRGAEHMCLLHPVIAQLL 1122
>UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG11146-PA - Tribolium castaneum
Length = 871
Score = 328 bits (807), Expect = 2e-88
Identities = 270/695 (38%), Positives = 334/695 (48%), Gaps = 119/695 (17%)
Query: 4 RQIYETAFDCKIARSXXXXXXXXRVSNHPALLQAEERKIISSASSAFEAVERSEPDFKGR 63
R +YETAFDC+I++S +VSNHP L+Q + SA + + P + R
Sbjct: 263 RHVYETAFDCRISKSDDDLDQIDKVSNHPVLVQLNNARENRPGPSA----DSNTP--QNR 316
Query: 64 RKVTMKTDSVRRSKIPTIRQKRENENNACALSEELEKVHIEGEERVASNS-QLPLRGYXX 122
RKVT+ + +E+ N+ A+S++L+++ + E V S + LPLRGY
Sbjct: 317 RKVTLLCP----------KPSQEDNNSVGAISQKLQEMRLPEEASVVSGALSLPLRGYTP 366
Query: 123 XXXXXXXXXXKFQQKDGSAMNSIKSAPNLPQAQPAHP--RLKDLRLPVKSLRARDTPTSS 180
KF K+ MNSI+SAPNLP +HP RLKDL LPVKSLR R +P SS
Sbjct: 367 SPPSTAPLPTKFPGKE-LVMNSIRSAPNLP----SHPKSRLKDLHLPVKSLRGR-SPNSS 420
Query: 181 DASMDVKGSVSTELDIXXXXXXXXXXXXXXXXXAQSKDGIFLEIKGRPTSDSDTPE--MN 238
S+ ++ S DI SK + E KGRP+ + E +
Sbjct: 421 SGSLQIQRSA---FDIEF---------------GNSK--LISEFKGRPSQPKEMKEWPLK 460
Query: 239 RYTGPKGVGPIMEFKGRPGVIRPRRKYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 298
R+ G K I+EFKGR R R KY
Sbjct: 461 RHKGTKD--NILEFKGR----RRRHKYSSTESMTASSSGGSMESIKSSTSEGNRSTTSSD 514
Query: 299 XXXXXXXXXXXXXXXXVPFSKSHHMQLGFGHHHPAKLNILSPISDKSSQEPASETSDNNK 358
H + KL+ILSPISDKSSQEP SETSDNN+
Sbjct: 515 SRQSSSLSSHSSDSGGTKAYCGTQNSSFLAHAN--KLHILSPISDKSSQEPISETSDNNR 572
Query: 359 NNNSQKVSPEEGDTGNATIQTAVEIIAKPKXXXXXXXXXXXXTFRHSATGDAEIQGSDSG 418
NNNSQK SPEE AT +T K K F GD EIQGSDSG
Sbjct: 573 NNNSQKCSPEEA----ATPETM-----KVKRRLPQNKNLLNLGFH---AGDLEIQGSDSG 620
Query: 419 ISIHSREGVDSRNAFINFKNSNTGEERKNDDVDLSDLPFDMPKLX----------XXXXX 468
ISI SREG+ SR D SDLPFDMPKL
Sbjct: 621 ISIQSREGIKSRQQ------------------DFSDLPFDMPKLRRRRMITQDACTSGSA 662
Query: 469 XXXDLRTLPFDMPKLRRKLRGQSLQLNDEFGGGISNASSSQSV-EDLNQG-------NKL 520
DLR LPFDMPKLRR+LR +Q + E +S ASSSQSV E QG +
Sbjct: 663 TSVDLRDLPFDMPKLRRRLR---IQPSTE--SSVSQASSSQSVIEADRQGSANLVLVSSF 717
Query: 521 KSSLKLNF------DXXXXXXXXKGLHLNL-GPIAPP-RDLVDATLPLDRQGWYHGTLAR 572
+ L LN GL +NL P PP D++D LPL++QGW+HG + R
Sbjct: 718 RPKLTLNLGELDLRQRPGLGLSLVGLGMNLNNPENPPTADVIDVNLPLEKQGWFHGAITR 777
Query: 573 VEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGA--EGYTLGGASTAF 630
VEAE++LR EG+FLVRNSES K DYSLSLKS RGFMHMRI + E Y LG S F
Sbjct: 778 VEAENVLRMLREGSFLVRNSESTKQDYSLSLKSARGFMHMRIQKDGNDECYILGQFSKPF 837
Query: 631 PSVPALMRHYVTAQRLPVRGAEHMALSTPLPAVLL 665
S+P ++RH+ RLP+RGAEHM L P+ A LL
Sbjct: 838 HSIPEMIRHF-CINRLPIRGAEHMCLLQPVIAQLL 871
>UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1182
Score = 256 bits (628), Expect = 1e-66
Identities = 180/408 (44%), Positives = 214/408 (52%), Gaps = 71/408 (17%)
Query: 321 HHMQLG---FGHHHPAKLNILSPISDKSSQEPASETSDNNKNNNSQKVSPEEGDTGNAT- 376
HH Q G F HH KL+ILSPISDKSSQEPASETSDNN+NNNSQK SPEE GN T
Sbjct: 783 HHQQTGLSSFLTHHATKLHILSPISDKSSQEPASETSDNNRNNNSQKASPEE--LGNPTA 840
Query: 377 ---------IQTAVEIIAKP---------KXXXXXXXXXXXXTFRHSATGDAEIQGSDSG 418
I A +I+ P K + S++GDAEIQGSDSG
Sbjct: 841 EQQQQQQQQIVNASVVISNPTTPTDSSFKKRRTPQNKNLINLALQSSSSGDAEIQGSDSG 900
Query: 419 ISIHSREGVDSRNAF---------INFKNSNTGEERKNDDVD----LSDLPFDMPKLX-- 463
ISI SR G+ F + + + N +D LSDLPFDMPKL
Sbjct: 901 ISIESRAGIKCNKPFGFQPIKPPQLQLQQQQPQLDNINQMLDNEQELSDLPFDMPKLRRR 960
Query: 464 ---------XXXXXXXXDLRTLPFDMPKLRRKLRGQSLQLNDEFGGGISNASSSQSVEDL 514
DL+ LPFDMPKLRR+LR S ASSS SV D+
Sbjct: 961 RMLMQQDANTSGSATSVDLKDLPFDMPKLRRRLR-----CTQSTESSTSQASSSLSVRDV 1015
Query: 515 NQ------GNKLKSSLKLNFDXXXXXXXXK---------GLHLNLGPIAPPRDLVDATLP 559
+ G + + LN D GL L L DLVD LP
Sbjct: 1016 DPPPALFGGGLARPKMTLNLDGGNGQQLLGLKKPGGLNLGLSLELTASRGSADLVDVELP 1075
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
L+RQGWYHG++ R+EAE++LR EG++LVRNSES K DYSLSLKS RGFMHMRI + E
Sbjct: 1076 LERQGWYHGSITRIEAEAVLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEE 1135
Query: 620 --GYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPAVLL 665
Y LG S F S+P ++RH+ + RLP+RGAEHM L P+ A LL
Sbjct: 1136 LNAYILGQFSKPFDSIPEMVRHF-SINRLPIRGAEHMCLLHPVIAQLL 1182
Score = 94.7 bits (225), Expect = 7e-18
Identities = 87/280 (31%), Positives = 137/280 (48%), Gaps = 48/280 (17%)
Query: 4 RQIYETAFDCKIARSXXXXXXXXRVSNHPAL---LQAEERKIISSASSAFEAVERSEPDF 60
RQIYETAFDCK++RS R++NHP L ++ +S ASS+ E+ +S+P
Sbjct: 422 RQIYETAFDCKVSRSDDDLDDLDRITNHPLLISQIRNGSAAPLSRASSSTESSRQSQPTL 481
Query: 61 -----KGRRKVTMKTDSVRRSKIPTI-RQKRE-----------NENNACALSEELEKVHI 103
+ ++ K S R K P + RQ+++ ++ +LS+++E + +
Sbjct: 482 QQTTHQASKEHRRKPGSALRPKAPILSRQQQQQQQQQQQPQQPSDGTIASLSQDIESLQM 541
Query: 104 EGEERVASNSQLPLRGYXX-XXXXXXXXXXKFQQKDGSAMNSIKSAPNLP--QAQPAHPR 160
+ +++ + RGY KF + +I+SAPNLP Q Q R
Sbjct: 542 NSNDEKSNSPRASGRGYGTPSPPSTAPLPAKFHNNREHLLLNIRSAPNLPSQQQQEQQQR 601
Query: 161 LKDLRLPVK-SLRARD-TPTSSDAS-MDVKGSVSTELDIXXXXXXXXXXXXXXXXXAQSK 217
LKD+RLPVK SLRA++ +P SS+ S +++KG + +SK
Sbjct: 602 LKDMRLPVKSSLRAKENSPQSSENSILEIKGRPKS-------------------FAMESK 642
Query: 218 DGIFLEIKGRPTSDSDTPEMNRYTGPKGVG-PIMEFKGRP 256
+ + LE KGRP ++ P+ R G P+MEFKGRP
Sbjct: 643 E-LILEFKGRPL-EASPPQRPRPRSLIREGKPVMEFKGRP 680
>UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; Aedes
aegypti|Rep: Putative uncharacterized protein - Aedes
aegypti (Yellowfever mosquito)
Length = 1044
Score = 250 bits (613), Expect = 7e-65
Identities = 171/375 (45%), Positives = 209/375 (55%), Gaps = 47/375 (12%)
Query: 334 KLNILSPISDKSSQEPASETSDNNKNNNSQKVSPEEGDTGNATIQTAVEIIAKPKXXXXX 393
KLNILSPISDKSSQEP SETSD N+NN SQK SP+E T A + E K
Sbjct: 674 KLNILSPISDKSSQEPGSETSDINRNN-SQKQSPDETVTTGAICKKESEENEAVKIIVPK 732
Query: 394 XXXXXXXTFRHSATGDAEIQGSDSGISIHSREGVDSRNAFINF--KNSNTGEERKNDDV- 450
TG EIQGSDSGIS+HSRE V SR F+N + ++ G E+ +
Sbjct: 733 VRRPAPNKALLLITGP-EIQGSDSGISLHSREDVKSRTNFLNLGIQRASLGLEKSDHGKS 791
Query: 451 ----DLSDLPFDMPKLX-----------XXXXXXXXDLRTLPFDMPKLRRKLR------- 488
D SDLPFDMPKL D+ LPFDMPKLRR+LR
Sbjct: 792 AVTQDFSDLPFDMPKLRRRRAHMQQEPCTSGSVTSMDVGDLPFDMPKLRRRLRLSQNQTQ 851
Query: 489 -------GQSLQLNDEFGGGISNASSSQSVEDLNQ-----GNKLKSSLKLNFDXXXXXXX 536
G LQ + E G+S ASSS S+ D + G K SL LN +
Sbjct: 852 IAIPSTSGILLQTSTE-SSGLSQASSSLSMRDSDNKAAIAGGFYKQSLTLNLNECNAKPV 910
Query: 537 XK----GLHLNLGPIAPPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNS 592
K L LN I +L+DAT+PLDRQGWYHG+++R++AE +LR EG+FLVRNS
Sbjct: 911 KKFGTLDLGLNFNTIRANIELIDATIPLDRQGWYHGSISRIDAEKILRPLGEGSFLVRNS 970
Query: 593 ESAKHDYSLSLKSTRGFMHMRICRGAE--GYTLGGASTAFPSVPALMRHYVTAQRLPVRG 650
ES + DYSL+LKS +GFMHMRI R E + LG S FP++P ++RH+ RLPVRG
Sbjct: 971 ESTRQDYSLTLKSAKGFMHMRIQRDHETGQFILGQFSRPFPTIPDMIRHF-CLNRLPVRG 1029
Query: 651 AEHMALSTPLPAVLL 665
AEHM L P+ A +L
Sbjct: 1030 AEHMCLLEPVIAQIL 1044
Score = 107 bits (257), Expect = 9e-22
Identities = 74/196 (37%), Positives = 100/196 (51%), Gaps = 10/196 (5%)
Query: 3 TRQIYETAFDCKIARSXXXXXXXXRVSNHPALLQAEERKIISSASSAFEAVERSEPDFKG 62
TRQIYETAFD KI RS RV+N LLQ + SS S+ + + D
Sbjct: 377 TRQIYETAFDSKITRSDDDLDEVDRVTNQSVLLQLNKSN-NSSTSNMVSSQNKENRDRSK 435
Query: 63 RRKVTMKTDSVRRSKIPTIRQKRENENNACA-LSEELEKVHIEGE------ERVASNSQL 115
R ++ S++ I+ E EN+A A LS++LEK+ I+ + S+SQL
Sbjct: 436 RGEIKRSKSSLKAPSSTQIQTTAEIENSAEANLSQDLEKLQIDKQLDNITNANSTSSSQL 495
Query: 116 PLRGYXXXXXXXXXXXXKFQQK-DGSAMNSIKSAPNLPQAQPA-HPRLKDLRLPVKSLRA 173
PLRGY KF K + +NSIKSAPNLP + A HPRLKDLRL ++++R
Sbjct: 496 PLRGYTPSPPSTAPLPMKFPGKHERFFINSIKSAPNLPSSNAAQHPRLKDLRLDIQAIRN 555
Query: 174 RDTPTSSDASMDVKGS 189
+ P S + S
Sbjct: 556 SEVPPSGSCDGSINDS 571
>UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000018199 - Anopheles gambiae
str. PEST
Length = 710
Score = 201 bits (490), Expect = 6e-50
Identities = 150/390 (38%), Positives = 197/390 (50%), Gaps = 59/390 (15%)
Query: 334 KLNILSPISDKSSQEPASETSD-NNKNNNSQK---VSPEEGD--TGNATIQTAVEIIAKP 387
KLNILSPISDKSSQEP SETSD NN+NNNSQK + +EG+ G + T
Sbjct: 322 KLNILSPISDKSSQEPGSETSDINNRNNNSQKHGTLGKKEGEESAGGGVVGTEAVKTNVT 381
Query: 388 KXXXXXXXXXXXXTFRHSATGDAEIQGSDSGISI------HSREG-----------VDSR 430
K T + ++ Q G I + ++G + SR
Sbjct: 382 KRRSAPNKALLLITGKLGFGWESLAQWEKVGTFIDVDKFYNEKKGTKTNENWIYSDLKSR 441
Query: 431 NAFIN--FKNSNTGEERKNDD--------VDLSDLPFDMPKLX-----------XXXXXX 469
F+N + ++ G++++ D DLSDLPFDMPKL
Sbjct: 442 TNFLNASLQRASLGQDKQGDHGKGQSGLPQDLSDLPFDMPKLRRRRAHLQQEPCTSGSVT 501
Query: 470 XXDLRTLPFDMPKLRRKLRGQ---SLQLNDE-----FGGGISNASSSQSVEDLNQGNKLK 521
D+ LPFDMP Q SL + D GG + V + K
Sbjct: 502 SVDVGDLPFDMPNTESSGLSQASSSLSMRDSDSKLALAGGKYTLPPRRRVPIAVRARFFK 561
Query: 522 SSLKLNFDXXXXXXXXK----GLHLNLGPIAPPRDLVDATLPLDRQGWYHGTLARVEAES 577
SL LN + K L LNLG P DL+DA++PLDRQGWYHG+++R++AE
Sbjct: 562 QSLTLNLNECGQRPPKKFGTLDLGLNLGTNRPNVDLIDASIPLDRQGWYHGSISRIDAEK 621
Query: 578 LLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG--YTLGGASTAFPSVPA 635
+LR EG+FLVRNSES + DYSL+LKS +GFMHMRI R A+ + LG S FP++P
Sbjct: 622 ILRPLSEGSFLVRNSESTRQDYSLTLKSAKGFMHMRIQRDADSGQFILGQFSRPFPTIPD 681
Query: 636 LMRHYVTAQRLPVRGAEHMALSTPLPAVLL 665
++RH+ RLPVRGAEHM L P+ A +L
Sbjct: 682 MIRHF-CLNRLPVRGAEHMCLLEPVIAQIL 710
Score = 86.6 bits (205), Expect = 2e-15
Identities = 74/203 (36%), Positives = 102/203 (50%), Gaps = 23/203 (11%)
Query: 3 TRQIYETAFDCKIARSXXXXXXXXRVSNHPALLQAEERKIISSASSAFEAVERSEPDFKG 62
TRQIYETAFD KI RS R++N LLQ + S++SSA V P
Sbjct: 8 TRQIYETAFDSKITRSDDDLDEVDRITNQSVLLQLTK----SNSSSASNMVTGGAPPASR 63
Query: 63 RRKVTMKTDSVRRSKIPT-------IRQKRENENNACALSEEL-EKVHIEGE-ERVA--- 110
+++ K SK P+ Q E A L+++L EK+ ++ + + +A
Sbjct: 64 TKRLETKRTKSASSKTPSGGGQDIAGAQPALEEAKADQLAQDLQEKLQLDKQMDNIANAN 123
Query: 111 --SNSQLPLRGYXXXXXXXXXXXXKFQQK-DGSAMNSIKSAPNLP--QAQPAHPRLKDLR 165
S+SQLPLRGY KF K + ++SIKSAPNLP A HPRLKDLR
Sbjct: 124 STSSSQLPLRGYTPSPPSTAPLPMKFPGKHERFFISSIKSAPNLPSSNAGAQHPRLKDLR 183
Query: 166 LPVKSLRARDTP--TSSDASMDV 186
L ++++R D +S D S+ V
Sbjct: 184 LDIQNVRNNDGAGGSSCDGSIAV 206
>UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146-PA -
Drosophila melanogaster (Fruit fly)
Length = 1416
Score = 177 bits (431), Expect = 8e-43
Identities = 113/251 (45%), Positives = 138/251 (54%), Gaps = 37/251 (14%)
Query: 451 DLSDLPFDMPKLX-----------XXXXXXXXDLRTLPFDMPKLRRKLRGQSLQLNDEF- 498
DL DLPFDMPKL DL LPFDMPKLRR+LR ++N+
Sbjct: 1167 DLRDLPFDMPKLRRRKTLQQEAACTSGSATSVDLGELPFDMPKLRRRLRANQAEINNLLM 1226
Query: 499 ----GGGISNASSSQSV-EDLNQGNKL-----KSSLKLNFDXXXXXX------------X 536
GIS ASSS S+ +D +KL + +L LN +
Sbjct: 1227 HSTESSGISQASSSHSMRDDQKMSSKLDTALFRQNLTLNLNESRQATKQFGSLDLRGLNS 1286
Query: 537 XKGLHLNLGP-IAPPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESA 595
K L++NL DL+D T+PL+RQGWYHG + R+EAE+ LR EG+FLVRN ES
Sbjct: 1287 NKELNMNLSQGYVTAVDLIDVTIPLERQGWYHGAITRIEAETTLRPLSEGSFLVRNCEST 1346
Query: 596 KHDYSLSLKSTRGFMHMRICRGAEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHM 654
K DYSLSLK +GFMHMRI R G Y LG S F +VP ++RH+ RLPVRGAEHM
Sbjct: 1347 KQDYSLSLKGAKGFMHMRIQRNETGQYILGQFSRPFETVPEMIRHF-CLNRLPVRGAEHM 1405
Query: 655 ALSTPLPAVLL 665
L P+ A LL
Sbjct: 1406 CLIEPVIAQLL 1416
Score = 93.5 bits (222), Expect = 2e-17
Identities = 67/196 (34%), Positives = 100/196 (51%), Gaps = 16/196 (8%)
Query: 4 RQIYETAFDCKIARSXXXXXXXXRVSNHPALLQ------AEERKIISSASSAFE------ 51
RQIYETAFDCKIA+S R++N LLQ + K+ S+ + E
Sbjct: 647 RQIYETAFDCKIAKSDDDLDEVDRITNCSVLLQLSNGNGGDISKVTGSSKTRAECKRAKN 706
Query: 52 AVERSEPDFKGRRKVTMKTDSVRRSKIPTIRQKRENENNACALSEELEKVHIEGEERVAS 111
+ ++ + G V + K+ + ++N+N + +++ V G AS
Sbjct: 707 SKNQALQEQTGEAHVQVHHVEAELGKLQLSQVDQQNQNQNQSQNQQ-HGVSATGSGASAS 765
Query: 112 NS-QLPLRGYXXXXXXXXXXXXKFQQKDGS--AMNSIKSAPNLPQAQPAHPRLKDLRLPV 168
++ QLP+RGY KF K MNSI+SAPNLP A PAHPRL+DLRLP+
Sbjct: 766 STQQLPVRGYTPSPPSTAPLPMKFPGKHDRYLNMNSIRSAPNLPAANPAHPRLRDLRLPI 825
Query: 169 KSLRARDTPTSSDASM 184
+S+R + +S+D S+
Sbjct: 826 QSMRHQCGGSSNDNSL 841
Score = 56.8 bits (131), Expect = 2e-06
Identities = 37/98 (37%), Positives = 52/98 (53%), Gaps = 9/98 (9%)
Query: 333 AKLNILSPISDKSSQEPASETSDNNKNNNSQKVSP-----EEGDTGNATIQTAVEIIAKP 387
+KL+ILSPISDKSSQEPAS ++ SQ+++P ++ T A V++ A
Sbjct: 1009 SKLHILSPISDKSSQEPASASASEQSQQPSQQLAPMASQEDDSTTSGAPAGNQVQVNASL 1068
Query: 388 KXXXXXXXXXXXXTFRHSATGDAEIQGSDSGISIHSRE 425
K + + E+ GSDSGIS+HSRE
Sbjct: 1069 KQPRSNRGAPNKALLQLA----DELLGSDSGISLHSRE 1102
>UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)); n=10;
Euteleostomi|Rep: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)) - Mus
musculus (Mouse)
Length = 446
Score = 125 bits (302), Expect = 3e-27
Identities = 59/120 (49%), Positives = 86/120 (71%), Gaps = 2/120 (1%)
Query: 542 LNLGPIAPPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSL 601
L + P +P + D LPL+ Q WYHG ++R +AE+LLR E ++LVRNSE++K+D+SL
Sbjct: 323 LGMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSL 382
Query: 602 SLKSTRGFMHMRICRGAE-GYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
SLKS++GFMHM++ R E Y LG S F SVP ++ HY +++LP++GAEHM+L P+
Sbjct: 383 SLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHY-ASRKLPIKGAEHMSLLYPV 441
>UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21;
Amniota|Rep: Shb-like adapter protein, Shf - Homo
sapiens (Human)
Length = 480
Score = 124 bits (300), Expect = 6e-27
Identities = 58/120 (48%), Positives = 86/120 (71%), Gaps = 2/120 (1%)
Query: 542 LNLGPIAPPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSL 601
L++ P +P + D LPL+ Q WYHG ++R +AE+LLR E ++LVRNSE++K+D+SL
Sbjct: 357 LSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSL 416
Query: 602 SLKSTRGFMHMRICRGAEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
SLKS++GFMHM++ R Y LG S F SVP ++ HY +++LP++GAEHM+L P+
Sbjct: 417 SLKSSQGFMHMKLSRTKNNKYVLGQNSPPFSSVPEIVHHY-ASRKLPIKGAEHMSLLYPV 475
>UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B;
n=29; Euteleostomi|Rep: SH2 domain-containing adapter
protein B - Homo sapiens (Human)
Length = 509
Score = 124 bits (298), Expect = 1e-26
Identities = 55/107 (51%), Positives = 81/107 (75%), Gaps = 1/107 (0%)
Query: 554 VDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMR 613
VD +PL++Q WYHG ++R +AE+LLR E ++LVRNS+++KHDYSLSL+S +GFMHM+
Sbjct: 399 VDPAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMK 458
Query: 614 ICRGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
+ + E Y LG S F SVP ++ HY T ++LP++GAEH++L P+
Sbjct: 459 LAKTKEKYVLGQNSPPFDSVPEVI-HYYTTRKLPIKGAEHLSLLYPV 504
>UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 457
Score = 120 bits (288), Expect = 2e-25
Identities = 56/110 (50%), Positives = 80/110 (72%), Gaps = 2/110 (1%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM 612
+VD TLPL++Q WYHG+++R EAE+ L+ E +FLVR+SESA YS++LK+++G +H+
Sbjct: 346 IVDPTLPLEKQSWYHGSVSRQEAEAQLQQCREASFLVRDSESATSKYSIALKTSQGCVHI 405
Query: 613 RICRGAE-GYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLP 661
+ + E GYTL +S FPS+P ++ HY T QRLP GAEHM L P+P
Sbjct: 406 IVAQTKECGYTLEKSSCVFPSIPEVVHHYCT-QRLPFTGAEHMTLQHPVP 454
>UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep:
Zgc:158798 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 391
Score = 116 bits (278), Expect = 3e-24
Identities = 55/108 (50%), Positives = 80/108 (74%), Gaps = 2/108 (1%)
Query: 554 VDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMR 613
VD +LPL++Q WYHG+L+R EAESLL E ++LVRNSE+++ DYSLSL+S +GFMHM+
Sbjct: 280 VDPSLPLEKQVWYHGSLSRSEAESLLTLCKECSYLVRNSETSRLDYSLSLRSCQGFMHMK 339
Query: 614 ICRGAEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
+ +G Y LG S F ++P ++ HY T +LP++GAEH++L P+
Sbjct: 340 FSQCKDGRYILGQNSPPFETIPEVI-HYYTTHKLPIKGAEHLSLLFPV 386
>UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 321
Score = 112 bits (269), Expect = 3e-23
Identities = 53/108 (49%), Positives = 76/108 (70%), Gaps = 2/108 (1%)
Query: 554 VDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMR 613
VD LPL++Q WYHG L R EAESLL E ++LVR S+++++DYSLSL+S GFMHM+
Sbjct: 210 VDPMLPLEKQVWYHGALTRSEAESLLTLCKECSYLVRKSQTSRNDYSLSLRSCHGFMHMK 269
Query: 614 ICRGAEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
+ +G + LG S F S+P ++ H+ T +LP+RGAEH++L P+
Sbjct: 270 FSQSRDGKFILGENSPPFDSIPEVI-HFYTTNKLPIRGAEHLSLLFPV 316
>UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D;
n=13; Mammalia|Rep: SH2 domain-containing adapter
protein D - Homo sapiens (Human)
Length = 340
Score = 110 bits (265), Expect = 1e-22
Identities = 58/117 (49%), Positives = 80/117 (68%), Gaps = 3/117 (2%)
Query: 546 PIAP-PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
P +P P + VD LPL++Q W+HG L R +AESLL EG++LVR SE+ D SLSL+
Sbjct: 220 PRSPQPAERVDPALPLEKQPWFHGPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLR 279
Query: 605 STRGFMHMRICRGAEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
S++GF+H++ R E LG S FPSVP L+ HY +++ LPV+GAEH+AL P+
Sbjct: 280 SSQGFLHLKFARTRENQVVLGQHSGPFPSVPELVLHY-SSRPLPVQGAEHLALLYPV 335
>UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E;
n=16; Euteleostomi|Rep: SH2 domain-containing adapter
protein E - Homo sapiens (Human)
Length = 495
Score = 103 bits (247), Expect = 2e-20
Identities = 49/112 (43%), Positives = 74/112 (66%), Gaps = 2/112 (1%)
Query: 554 VDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMR 613
VD LPL++Q WYHG ++R EAES L+ E +LVRNSES YS++LK+++G +H+
Sbjct: 384 VDPGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHII 443
Query: 614 ICRGAEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPAVL 664
+ + + YTL S F S+P ++ HY + ++LP +GAEHM L P+ + L
Sbjct: 444 VAQTKDNKYTLNQTSAVFDSIPEVV-HYYSNEKLPFKGAEHMTLLYPVHSKL 494
>UniRef50_UPI00006A214E Cluster: SH2 domain-containing adapter
protein E.; n=1; Xenopus tropicalis|Rep: SH2
domain-containing adapter protein E. - Xenopus
tropicalis
Length = 437
Score = 100 bits (239), Expect = 1e-19
Identities = 45/112 (40%), Positives = 77/112 (68%), Gaps = 2/112 (1%)
Query: 552 DLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMH 611
D VD T+PL++Q WYHG++ R +AESLL E ++L+RNS S YS++LK+++G +H
Sbjct: 324 DKVDPTVPLEKQSWYHGSVTRDQAESLLDSCPEASYLLRNSGSGNSKYSIALKTSQGCVH 383
Query: 612 MRICRGAEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPA 662
+ + + +TL AF S+P ++ HY ++Q+LP +G++H++L P+P+
Sbjct: 384 IIVAQTKNNKFTLSQMCGAFNSIPEVVHHY-SSQKLPFKGSKHISLLHPVPS 434
>UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homology
2 domain-containing transforming protein D; n=1; Macaca
mulatta|Rep: PREDICTED: similar to src homology 2
domain-containing transforming protein D - Macaca
mulatta
Length = 221
Score = 99.1 bits (236), Expect = 3e-19
Identities = 50/98 (51%), Positives = 69/98 (70%), Gaps = 2/98 (2%)
Query: 564 GWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG-YT 622
GW+HG L R +AESLL EG++LVR SE++ D SLSL+S++GF+H++ R E
Sbjct: 120 GWFHGPLNRADAESLLSLCKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTRENQVV 179
Query: 623 LGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
LG S FPSVP L+ HY +++ LPV+GAEH+AL P+
Sbjct: 180 LGQHSGPFPSVPELVLHY-SSRPLPVQGAEHLALLYPV 216
>UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF15044, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 253
Score = 89.4 bits (212), Expect = 3e-16
Identities = 44/100 (44%), Positives = 67/100 (67%), Gaps = 5/100 (5%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRIC--RGAE--G 620
WYHG+++R +AE+ L+ E +FLVR+SES YS++LK+++ +H+ + +G + G
Sbjct: 154 WYHGSVSRQQAEAQLQRCREASFLVRDSESGTSKYSIALKTSQSCVHIIVAQTKGVKGLG 213
Query: 621 YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
+TL +S FPS+P L+ HY T RLP GAEHM L P+
Sbjct: 214 FTLDQSSCVFPSIPELVHHYCT-HRLPFTGAEHMTLQHPV 252
>UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04657 protein - Schistosoma
japonicum (Blood fluke)
Length = 153
Score = 83.0 bits (196), Expect = 2e-14
Identities = 44/104 (42%), Positives = 66/104 (63%), Gaps = 3/104 (2%)
Query: 558 LPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
LPL+ Q W+H +L R EAE L+R+ EG+FLVR SE+ +D+SL++K + F+HM+I R
Sbjct: 48 LPLEEQPWFHPSLTRSEAEELIRNEPEGSFLVRPSETCPNDFSLTIKH-KTFLHMKITRN 106
Query: 618 AEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
G + LG S + SV ++ HY +PV GA + L+ P+
Sbjct: 107 NAGQFILGEYSQPYSSVSQMIYHYART-LVPVLGAYSVTLTHPV 149
>UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14995, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 123
Score = 72.9 bits (171), Expect = 2e-11
Identities = 37/78 (47%), Positives = 52/78 (66%), Gaps = 1/78 (1%)
Query: 558 LPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
L L R WYHG+L+R EAE LL E ++LVR S++ +YSLSL+S +GFMHM++ +
Sbjct: 45 LCLWRSRWYHGSLSRSEAECLLTLCKECSYLVRTSQTNHSEYSLSLRSCQGFMHMKLTQC 104
Query: 618 AEG-YTLGGASTAFPSVP 634
+G Y LG S F ++P
Sbjct: 105 KDGKYVLGQNSPLFDTIP 122
>UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:
ENSANGP00000020137 - Anopheles gambiae str. PEST
Length = 185
Score = 64.1 bits (149), Expect = 1e-08
Identities = 27/63 (42%), Positives = 41/63 (65%)
Query: 558 LPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
+ + WY+G + R +AE LL + EGAFL+R SES+ D+SLS+K + G H ++ R
Sbjct: 27 IEMKNHDWYYGRITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCSDGVQHFKVLRD 86
Query: 618 AEG 620
A+G
Sbjct: 87 AQG 89
>UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein 22,
isoform a; n=3; Caenorhabditis|Rep: Temporarily assigned
gene name protein 22, isoform a - Caenorhabditis elegans
Length = 395
Score = 62.9 bits (146), Expect = 3e-08
Identities = 37/104 (35%), Positives = 57/104 (54%), Gaps = 3/104 (2%)
Query: 558 LPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
+P+++Q WY G ++R AE LL EG FLVR+SES D S+S++ H ++ +
Sbjct: 294 IPMEQQPWYFGRISRERAEDLLLHGREGEFLVRDSESNPGDLSISMRGIERNKHFKV-QN 352
Query: 618 AEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLP 661
+G G T F + AL+ HY T+ + E + L+ PLP
Sbjct: 353 VDGLLKIGNRT-FVDMNALINHYTTSP-IFSSPTEKLFLTGPLP 394
>UniRef50_Q08BW5 Cluster: Zgc:154062; n=1; Danio rerio|Rep:
Zgc:154062 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 212
Score = 60.5 bits (140), Expect = 1e-07
Identities = 34/88 (38%), Positives = 52/88 (59%), Gaps = 6/88 (6%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
LD GWY G ++ EA S+L+ A EG FL+R+S + +LS+K+ RG ++RI
Sbjct: 46 LDASGWYWGGISASEAHSVLKGASEGTFLIRDSSHPDYMLTLSVKTVRGPTNVRIEYRQC 105
Query: 620 GYTLGGASTA------FPSVPALMRHYV 641
++L +S A FP V +L++HYV
Sbjct: 106 RFSLDSSSPARSHLQSFPDVHSLVQHYV 133
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 60.5 bits (140), Expect = 1e-07
Identities = 32/93 (34%), Positives = 48/93 (51%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P + + L++ WYHG ++R AE LL G+FLVR SES+ S+SL+
Sbjct: 158 PSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRV 217
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHYVT 642
H RI A+G A + F ++ L+ H+ T
Sbjct: 218 YHYRINTTADGKVYVTAESRFSTLAELVHHHST 250
>UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3;
Xenopus tropicalis|Rep: Putative uncharacterized protein
- Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 379
Score = 59.7 bits (138), Expect = 2e-07
Identities = 30/103 (29%), Positives = 57/103 (55%), Gaps = 4/103 (3%)
Query: 559 PLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI-CRG 617
PL Q WYHG L+++EAE L++ G+F++R + +Y +S++ + H+++ C
Sbjct: 275 PLQTQVWYHGKLSKLEAEKYLQNCKPGSFVIRIEQDI--EYFMSVRGSHSTQHLKVKCIE 332
Query: 618 AEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
E + LG + +F + L+ HY+ L ++ E + L P+
Sbjct: 333 NEHFMLGESGPSFTCILELVEHYM-KHPLLLQNEEQLFLQCPV 374
>UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras
GTPase-activating protein 1 (GTPase-activating protein)
(GAP) (Ras p21 protein activator) (p120GAP) (RasGAP);
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Ras GTPase-activating protein 1
(GTPase-activating protein) (GAP) (Ras p21 protein
activator) (p120GAP) (RasGAP) - Strongylocentrotus
purpuratus
Length = 628
Score = 59.3 bits (137), Expect = 3e-07
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 559 PLDRQGWYHGTLARVEA-ESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
P + + W+HG +++ EA E+L +D D G FL+RNS+ DYSLS + RI +
Sbjct: 231 PNEGKVWFHGNVSKEEAAETLWKDGDIGGFLIRNSDKNPGDYSLSFRGPNTIQRFRIQKQ 290
Query: 618 AEGYTLGGASTAFPSVPALMRHY 640
Y +GG + S+ A++ HY
Sbjct: 291 QRQYVMGG--RYYNSLDAIVDHY 311
Score = 57.6 bits (133), Expect = 1e-06
Identities = 35/93 (37%), Positives = 47/93 (50%), Gaps = 4/93 (4%)
Query: 550 PRDLVDATLPLDRQG-WYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTR 607
P + VDA L + WYHG L R AE L AD+ G++LVR SE Y LS R
Sbjct: 52 PEETVDANLTAPPENEWYHGCLDRQSAELRLNAADKPGSYLVRESERKPGSYVLSYLGQR 111
Query: 608 GFMHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
G H R+ + +GG F ++P L+ +Y
Sbjct: 112 GINHFRVTAVCGDFYVGGRQ--FQTLPELIGYY 142
>UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo
sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo
sapiens (Human)
Length = 498
Score = 58.8 bits (136), Expect = 4e-07
Identities = 30/93 (32%), Positives = 48/93 (51%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P + + L++ WYHG ++R AE LL G+FLVR SES+ S+SL+
Sbjct: 364 PSNYITPVNSLEKHSWYHGPVSRNAAEHLLSSGINGSFLVRESESSPGQRSISLRYEGRV 423
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHYVT 642
H RI ++G + + F ++ L+ H+ T
Sbjct: 424 YHYRINTASDGKLYVSSESRFNTLAELVHHHST 456
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis
mellifera
Length = 1439
Score = 58.4 bits (135), Expect = 6e-07
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 541 HLNLGPIA-PPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDY 599
H + G + P + V L++ WYHG + R AE LL G+FLVR SES+
Sbjct: 149 HSSTGQVGWVPSNYVTPVNSLEKHSWYHGRICRNAAEYLLSSGINGSFLVRESESSPGQR 208
Query: 600 SLSLKSTRGFMHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
S+SL+ H RI +EG + F ++ L+ H+
Sbjct: 209 SISLRYEGRVYHYRINEDSEGKMFVTTESKFNTLAELVHHH 249
>UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10;
Euteleostomi|Rep: Bcr-abl1 e6a2 chimeric protein - Homo
sapiens (Human)
Length = 585
Score = 58.4 bits (135), Expect = 6e-07
Identities = 30/93 (32%), Positives = 48/93 (51%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P + + L++ WYHG ++R AE LL G+FLVR SES+ S+SL+
Sbjct: 451 PSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRV 510
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHYVT 642
H RI ++G + + F ++ L+ H+ T
Sbjct: 511 YHYRINTASDGKLYVSSESRFNTLAELVHHHST 543
>UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21;
Eumetazoa|Rep: Bcr-abl1 e13a3 chimeric protein - Homo
sapiens (Human)
Length = 235
Score = 58.4 bits (135), Expect = 6e-07
Identities = 30/93 (32%), Positives = 48/93 (51%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P + + L++ WYHG ++R AE LL G+FLVR SES+ S+SL+
Sbjct: 101 PSNYITPANSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRV 160
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHYVT 642
H RI ++G + + F ++ L+ H+ T
Sbjct: 161 YHYRINTASDGKLYVSSESRFNTLAELVHHHST 193
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
kinase ABL1 - Homo sapiens (Human)
Length = 1130
Score = 58.4 bits (135), Expect = 6e-07
Identities = 30/93 (32%), Positives = 48/93 (51%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P + + L++ WYHG ++R AE LL G+FLVR SES+ S+SL+
Sbjct: 112 PSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRV 171
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHYVT 642
H RI ++G + + F ++ L+ H+ T
Sbjct: 172 YHYRINTASDGKLYVSSESRFNTLAELVHHHST 204
>UniRef50_Q6P8E0 Cluster: Suppressor of cytokine signaling 3; n=2;
Xenopus tropicalis|Rep: Suppressor of cytokine signaling
3 - Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 211
Score = 58.0 bits (134), Expect = 8e-07
Identities = 33/87 (37%), Positives = 51/87 (58%), Gaps = 5/87 (5%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI-CRGA 618
L+ G+Y TL+ EA+ LL D G+FL+R+S H ++LSL+++ G ++RI G
Sbjct: 50 LEASGYYWSTLSGTEAKKLLSDQPVGSFLIRDSSDHHHLFTLSLRTSAGITNLRIKLEGP 109
Query: 619 EGY--TLGGAST--AFPSVPALMRHYV 641
Y T+ GA + FP V L+ HY+
Sbjct: 110 SFYLETVAGAESPHTFPCVVKLVEHYM 136
>UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Rep:
Tyrosine kinase - Sycon raphanus
Length = 879
Score = 58.0 bits (134), Expect = 8e-07
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 7/109 (6%)
Query: 552 DLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMH 611
D +A ++ + WYHG ++R EA LL+ G FLVR S +H Y+L++K G H
Sbjct: 504 DTPEAHAGVEEEPWYHGEISRQEATGLLKKM--GDFLVRYSADKEH-YTLTVK-MEGIKH 559
Query: 612 MRICRGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
I EG+ G +PS+P L+ H+ RLPV L P+
Sbjct: 560 FIIQHNEEGFRFEG--DPYPSIPMLIDHHF-KNRLPVTRKSQAILRQPV 605
>UniRef50_Q4RX78 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
SCAF14979, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 220
Score = 57.6 bits (133), Expect = 1e-06
Identities = 30/83 (36%), Positives = 50/83 (60%), Gaps = 6/83 (7%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
WY G + +A + L++A EGAFLVR+S + +LS+++ RG +RI + + L
Sbjct: 57 WYWGAVTAAQAHAALQEASEGAFLVRDSSHPLYMLTLSVRTARGPTSIRIQYSSARFLLD 116
Query: 625 GASTA------FPSVPALMRHYV 641
+S A FP+VP+L++HY+
Sbjct: 117 SSSPARPSLSSFPNVPSLVQHYM 139
>UniRef50_Q06AL4 Cluster: Suppressor of cytokine signaling 1; n=5;
root|Rep: Suppressor of cytokine signaling 1 -
Gasterosteus aculeatus (Three-spined stickleback)
Length = 237
Score = 57.6 bits (133), Expect = 1e-06
Identities = 30/97 (30%), Positives = 51/97 (52%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM 612
+ + L+R +Y G L EA +LRDA G+FL+R+S ++LS G + +
Sbjct: 93 ITETASKLERSAFYWGPLGVEEAHRMLRDAPLGSFLIRDSRQKDVFFTLSYHGKSGPVSV 152
Query: 613 RICRGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVR 649
RI + ++L G FP++ AL+ HY + + +R
Sbjct: 153 RIDYKLQKFSLAGNERCFPTLFALLEHYANSPKRSLR 189
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
kinase FER - Homo sapiens (Human)
Length = 822
Score = 57.6 bits (133), Expect = 1e-06
Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Query: 559 PLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGA 618
PL Q WYHG + R+EA+ LL+ +G FLVR S +Y LS+ S H I
Sbjct: 454 PLAEQDWYHGAIPRIEAQELLK--KQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVD 511
Query: 619 EGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLP 661
Y G T F ++P L+ H+ T +++ + + L P+P
Sbjct: 512 NMYRFEG--TGFSNIPQLIDHHYTTKQV-ITKKSGVVLLNPIP 551
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=57; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 57.6 bits (133), Expect = 1e-06
Identities = 30/93 (32%), Positives = 47/93 (50%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P + + L++ WYHG ++R AE LL G+FLVR SES+ S+SL+
Sbjct: 61 PSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRV 120
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHYVT 642
H RI ++G + F ++ L+ H+ T
Sbjct: 121 YHYRINTASDGKLYVSPESRFNTLAELVHHHST 153
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=15; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Abelson murine leukemia virus
Length = 746
Score = 57.2 bits (132), Expect = 1e-06
Identities = 29/83 (34%), Positives = 45/83 (54%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
L++ WYHG ++R AE LL G+FLVR SES+ S+SL+ H RI ++
Sbjct: 8 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASD 67
Query: 620 GYTLGGASTAFPSVPALMRHYVT 642
G + + F ++ L+ H+ T
Sbjct: 68 GKLYVSSESRFNTLAELVHHHST 90
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1 - Nasonia
vitripennis
Length = 1522
Score = 56.8 bits (131), Expect = 2e-06
Identities = 30/91 (32%), Positives = 46/91 (50%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P + V L++ WYHG ++R AE LL G+FLVR SES+ S+SL+
Sbjct: 160 PSNYVTPVNSLEKHSWYHGRISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRV 219
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
H RI ++G + F ++ L+ H+
Sbjct: 220 YHYRINEDSDGKMYVTTESIFNTLAELVHHH 250
>UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 56.8 bits (131), Expect = 2e-06
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 561 DRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
D+ WYHG L RVE E +L G +LVR+S + DY LS+ + H I
Sbjct: 5 DQLPWYHGVLKRVETEGILNGKPPGVWLVRDSTTIPGDYVLSVSESGKVSHYIINNKGTM 64
Query: 621 YTLGGASTAFPSVPALMRHY 640
YT+G FP +P+++ Y
Sbjct: 65 YTIG--DQTFPDLPSIIEFY 82
>UniRef50_UPI0000F2066F Cluster: PREDICTED: similar to Src homology
2 domain containing F,; n=1; Danio rerio|Rep: PREDICTED:
similar to Src homology 2 domain containing F, - Danio
rerio
Length = 184
Score = 56.4 bits (130), Expect = 2e-06
Identities = 26/57 (45%), Positives = 41/57 (71%), Gaps = 2/57 (3%)
Query: 605 STRGFMHMRICRGAEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
S++GFMHM++ R + Y LG S F SVP ++ HY ++++LP++GAEHM+L P+
Sbjct: 124 SSQGFMHMKLSRTKDSKYVLGQNSCLFDSVPEII-HYYSSRKLPIKGAEHMSLLYPV 179
>UniRef50_Q4S861 Cluster: Chromosome 5 SCAF14709, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 5 SCAF14709, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 775
Score = 56.4 bits (130), Expect = 2e-06
Identities = 27/59 (45%), Positives = 42/59 (71%), Gaps = 2/59 (3%)
Query: 603 LKSTRGFMHMRICRGAEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
L+S++GFMHM++ R E Y LG S F SVP ++ H+ ++ +LP++GAEHM+L P+
Sbjct: 713 LRSSQGFMHMKLSRTKENKYILGQNSCPFDSVPEII-HFYSSCKLPIKGAEHMSLLYPV 770
>UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 312
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 562 RQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGY 621
R GWY G L R A+ L D G FLVR+SE+ KH +++S +S+ +H RI + +
Sbjct: 159 RYGWYWGKLTRSAAQKRLARQDNGTFLVRDSETEKHQFAISFRSSGITLHCRIDYKDKNW 218
Query: 622 TLGG--ASTAFPSVPALMRHYVTAQRLPV--RGAEHMALSTPLPAVL 664
+ G A T + ++ L+ + L V G + L+ P P L
Sbjct: 219 SFSGLTAPTHYATMIELIEDSMKKSELDVIGFGKQTCPLTPPFPVRL 265
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/91 (32%), Positives = 44/91 (48%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P + V L++ WYHG ++R AE LL G+FLVR SES+ S+SL+
Sbjct: 239 PSNYVTPLNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRV 298
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
H RI +G F ++ L+ H+
Sbjct: 299 YHYRISEDPDGKVFVTQEAKFNTLAELVHHH 329
>UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596;
n=2; Danio rerio|Rep: hypothetical protein LOC553596 -
Danio rerio
Length = 283
Score = 56.0 bits (129), Expect = 3e-06
Identities = 34/112 (30%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Query: 558 LPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
+ L W+ G ++R AE+ L D G+FLVR SESA ++S+S+ H ++ +
Sbjct: 53 ISLRPHAWFAGRISRHVAENRLHQRDCGSFLVRESESAPGEFSMSVSYGDHVQHFKVLKD 112
Query: 618 AEGYTLGGASTAFPSVPALMRHYVT-----AQRLPVRGAEHMALSTPLPAVL 664
EGY FPS+ L+ +Y T + + +R +H P+PA++
Sbjct: 113 REGYYFVW-EEIFPSLNQLVDYYKTNSIAKERTVFLRDLDHTLKKIPVPAMM 163
>UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth factor
receptor-bound protein 2; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Growth factor
receptor-bound protein 2 - Strongylocentrotus purpuratus
Length = 176
Score = 55.6 bits (128), Expect = 4e-06
Identities = 34/86 (39%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 557 TLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR 616
T P W+ T+ R AE LL GAFLVR SES++ YSLS+K H RI +
Sbjct: 6 TYPEIAMAWFFPTITRKNAELLLMQERNGAFLVRRSESSEGLYSLSVKYNESVQHFRILQ 65
Query: 617 GAEGYTLGGASTAFPSVPALMRHYVT 642
G FPS+ AL+ +Y T
Sbjct: 66 DTAG-KFHLWIVKFPSLDALVDYYRT 90
>UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6
SCAF14737, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 393
Score = 55.6 bits (128), Expect = 4e-06
Identities = 36/105 (34%), Positives = 51/105 (48%), Gaps = 8/105 (7%)
Query: 545 GPIAPPRDLVDATLPLDR-----QGWYHGTLARVEAESLLRDAD-EGAFLVRNSESAKHD 598
GP PP D P + WY+G + R +AE L EG FL+R+SES+ HD
Sbjct: 272 GPAGPPTPDCDYISPSGSGRFAGKEWYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHD 331
Query: 599 YSLSLKSTRGFMHMRICRGAEGYTLGGASTAFPSVPALMRHYVTA 643
+S+SLK+ H ++ Y +G F S+ L+ HY A
Sbjct: 332 FSISLKAQSKNKHFKVQLKESLYCIG--QRKFHSMEELVEHYKKA 374
>UniRef50_Q9NSE2 Cluster: Cytokine-inducible SH2-containing protein;
n=26; Tetrapoda|Rep: Cytokine-inducible SH2-containing
protein - Homo sapiens (Human)
Length = 258
Score = 55.6 bits (128), Expect = 4e-06
Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 6/106 (5%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
L GWY G++ EA L+ EG FLVR+S + ++LS+K+TRG ++RI
Sbjct: 77 LRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADS 136
Query: 620 GYTLGG------ASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTP 659
+ L AFP V +L++HYV + R TP
Sbjct: 137 SFRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAPTP 182
>UniRef50_UPI0000E49F60 Cluster: PREDICTED: hypothetical protein;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 514
Score = 55.2 bits (127), Expect = 5e-06
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 3/63 (4%)
Query: 605 STRGFMHMRIC--RGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPA 662
S +GFMHM+I ++GY LG S FPS+ ++ +Y T Q+L +RGAEHMAL P+
Sbjct: 453 SAKGFMHMKIVFNHQSDGYILGEFSKPFPSISEMICYY-TRQKLNIRGAEHMALLHPVID 511
Query: 663 VLL 665
LL
Sbjct: 512 QLL 514
>UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 921
Score = 55.2 bits (127), Expect = 5e-06
Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 559 PLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGA 618
PL++Q WYHG + R+E + LL +G FLVR S+ K Y LS+ + H +
Sbjct: 522 PLEQQTWYHGAIPRLEVQQLL--TKDGDFLVRKSQE-KPGYVLSVHWSGACKHFLVQNKD 578
Query: 619 EGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAE 652
Y L G S F ++P L++ Y T+Q+ + +E
Sbjct: 579 NMYCLDGES--FHTIPQLIQQYQTSQQHVTKKSE 610
>UniRef50_Q7YWN4 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 190
Score = 54.8 bits (126), Expect = 7e-06
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 4/114 (3%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
PRD P D + + + RVEAE L + + G +L+R+ + +LSL++T+G
Sbjct: 81 PRDESKRRRPSDSEIYMEQNMNRVEAEKRLENRNLGDYLLRS--RGEGSAALSLRATKGV 138
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPAV 663
+H++I E + + G F S+ + + Y LP+RGA+H+ L L V
Sbjct: 139 VHIKIEWNGEKWVI-GEGPLFRSISSAISFY-RRHPLPIRGADHLVLKNQLKPV 190
>UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03955 protein - Schistosoma
japonicum (Blood fluke)
Length = 190
Score = 54.8 bits (126), Expect = 7e-06
Identities = 28/76 (36%), Positives = 41/76 (53%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
WYHG ++R E LLR G+FLVR SESA S++++ H RI + + G
Sbjct: 78 WYHGAVSRQAGEHLLRSGITGSFLVRASESAPGQLSVTVRHLGRVYHYRISQDSRGLFYI 137
Query: 625 GASTAFPSVPALMRHY 640
+ FP+V L+ H+
Sbjct: 138 TEAHRFPTVVQLIEHH 153
>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
- Spongilla lacustris (Freshwater sponge)
Length = 505
Score = 54.8 bits (126), Expect = 7e-06
Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDA--DEGAFLVRNSESAKHDYSLSLKSTR 607
P + V LD + W+ G + RVEAE +L + G+FL+R+SE+ D+SLS+K
Sbjct: 107 PSNYVAEYKSLDAEEWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSVKDQD 166
Query: 608 GFMHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
H R+ R +G + F + L+ HY
Sbjct: 167 RVRHYRVRRLEDGSLFVTRRSTFQILHELVDHY 199
>UniRef50_Q4H2S5 Cluster: Suppressor of cytokine signaling; n=1;
Ciona intestinalis|Rep: Suppressor of cytokine signaling
- Ciona intestinalis (Transparent sea squirt)
Length = 406
Score = 54.4 bits (125), Expect = 9e-06
Identities = 38/126 (30%), Positives = 57/126 (45%), Gaps = 2/126 (1%)
Query: 489 GQSLQLNDEFGGGISNASSSQSVEDLNQGNKLKSSLKLNFDXXXXXXXXKGLHLNLGPIA 548
G+ QL +E + Q+ E L+ G ++ ++ D LH+ P
Sbjct: 180 GKPSQLQEEDTVVPDSTDVYQTPESLDHGIMGATAAPVSPDVNHTFHTLTSLHVP--PTM 237
Query: 549 PPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRG 608
L + L +QGWY G L R EAE L + G+FLVR+S ++ SLS +S
Sbjct: 238 RKNTLTNEFKKLAQQGWYWGPLTRSEAEDKLNETPNGSFLVRDSSDERYLLSLSFRSFGR 297
Query: 609 FMHMRI 614
+H RI
Sbjct: 298 TLHTRI 303
>UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 391
Score = 53.6 bits (123), Expect = 2e-05
Identities = 26/55 (47%), Positives = 36/55 (65%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI 614
L RQ WY G +++ EAE L DAD+G+FLVR+S ++ +LS KS +H RI
Sbjct: 239 LPRQPWYWGPMSQDEAEGKLDDADDGSFLVRDSSDDRYLLTLSFKSNGRTLHTRI 293
>UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF5507, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1116
Score = 53.6 bits (123), Expect = 2e-05
Identities = 37/104 (35%), Positives = 53/104 (50%), Gaps = 3/104 (2%)
Query: 565 WYHGTLARVEAESLLRDAD--EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYT 622
WY+G + RV+AE LL + +G+FLVR SES +Y++S +S H RI R + G
Sbjct: 250 WYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFHFRIQRSSIGAY 309
Query: 623 LGGASTAFPSVPALMRHYVTAQR-LPVRGAEHMALSTPLPAVLL 665
+F ++ L+ +Y R L V E A PL LL
Sbjct: 310 FVSDRISFATLGELISYYQRNNRSLGVLLEEPCAQQRPLTPSLL 353
Score = 43.2 bits (97), Expect = 0.023
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 563 QGWYHGTLARVEAES--LLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
Q W+ GTL R++A+S L + EGAFL+R SE Y LS++S H ++ + +
Sbjct: 67 QPWFFGTLNRLQAQSHLLAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQN 126
Query: 621 YTLGGASTAFPSVPALMRHY 640
F S+ L+ +Y
Sbjct: 127 RFYVEPGRRFSSLAELVDYY 146
>UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 18
SCAF14547, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 609
Score = 53.6 bits (123), Expect = 2e-05
Identities = 40/112 (35%), Positives = 53/112 (47%), Gaps = 10/112 (8%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI----C 615
L WYHG L R AE+LL G FLVR+S S DY L+ MH +I
Sbjct: 16 LSSHAWYHGPLRREAAEALLE--RNGDFLVRDSSSTPRDYVLTCFWMNMPMHFKIIRVVL 73
Query: 616 RGAEGYT---LGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPAVL 664
R +GY+ F ++PAL+R YV +R P+ A +S P+ L
Sbjct: 74 RPKKGYSRELFQFEEDRFDNIPALIRLYVGGRR-PISQASGAVISHPITRTL 124
>UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase
activating protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ras gtpase activating protein -
Nasonia vitripennis
Length = 879
Score = 52.8 bits (121), Expect = 3e-05
Identities = 36/98 (36%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Query: 565 WYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WYHG L R AE LRDA G++LVR S+ Y LS G H RI Y +
Sbjct: 77 WYHGRLDRFTAEERLRDASRLGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 136
Query: 624 GGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLP 661
GG F S+ L+ +Y L + E + TP P
Sbjct: 137 GGRQ--FNSLMDLVAYYTHCSDLLKK--ERLIHPTPPP 170
Score = 46.8 bits (106), Expect = 0.002
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Query: 552 DLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMH 611
DL D+ P W+H + + EA +L A G+FLVR S+++ DYSL
Sbjct: 233 DLDDSIDPNTVFSWFHPNVTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQR 292
Query: 612 MRICRGAEGYTLGGASTAFPSVPALMRHY 640
RI + Y +GG + F + A++ Y
Sbjct: 293 FRIEKKGVRYLMGGRT--FECLDAVINRY 319
>UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020257 - Anopheles gambiae
str. PEST
Length = 1192
Score = 52.8 bits (121), Expect = 3e-05
Identities = 40/105 (38%), Positives = 54/105 (51%), Gaps = 10/105 (9%)
Query: 559 PLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKST--RGFMHMRICR 616
PL + W+HG L R E LLR +EG FLVR E+ ++D S ++ S G H +
Sbjct: 822 PLHEEEWFHGVLPREEVVRLLR--NEGDFLVR--ETTRNDESQTVLSVCWNGHKHFIVQT 877
Query: 617 GAEG-YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
AEG Y G AFPS+ L+ H ++ LPV G L P+
Sbjct: 878 TAEGHYRFEG--PAFPSIQELIVHQYQSE-LPVTGRSGAVLRKPV 919
>UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54;
Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo
sapiens (Human)
Length = 380
Score = 52.8 bits (121), Expect = 3e-05
Identities = 30/90 (33%), Positives = 51/90 (56%), Gaps = 6/90 (6%)
Query: 565 WYHGTLARVEAESLLRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WY+G + R +AE L + EG FL+R+SES+ D+S+SLK++ H ++ Y +
Sbjct: 285 WYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYCI 344
Query: 624 GGASTAFPSVPALMRHYVTAQRLPVRGAEH 653
G F ++ L+ HY ++ P+ +EH
Sbjct: 345 G--QRRFHTMDELVEHY---KKAPIFTSEH 369
>UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22;
Amniota|Rep: GRB2-related adapter protein 2 - Homo
sapiens (Human)
Length = 330
Score = 52.8 bits (121), Expect = 3e-05
Identities = 30/94 (31%), Positives = 53/94 (56%), Gaps = 7/94 (7%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P++ +D P W+H L+R +AE+LL + G F++R S+S+ D+S+S++
Sbjct: 47 PKNFIDIQFPK----WFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDV 102
Query: 610 MHMRICRGAEG-YTLGGASTAFPSVPALMRHYVT 642
H ++ R +G Y L + FPS+ L+ +Y T
Sbjct: 103 QHFKVMRDNKGNYFLW--TEKFPSLNKLVDYYRT 134
>UniRef50_UPI000058773D Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 227
Score = 52.4 bits (120), Expect = 4e-05
Identities = 24/62 (38%), Positives = 36/62 (58%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM 612
L++ L GWYHG + EA+ L+ G FLVR+S ++ Y+LS+K+ RG +
Sbjct: 43 LINTLNSLQMSGWYHGAMTYREAKLKLKSCSNGTFLVRDSSDDRYLYTLSVKTPRGTTSV 102
Query: 613 RI 614
RI
Sbjct: 103 RI 104
>UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio
"Phospholipase C gamma 1.; n=1; Takifugu rubripes|Rep:
Homolog of Brachydanio rerio "Phospholipase C gamma 1. -
Takifugu rubripes
Length = 1071
Score = 52.4 bits (120), Expect = 4e-05
Identities = 30/77 (38%), Positives = 45/77 (58%), Gaps = 3/77 (3%)
Query: 565 WYHGTLARVEAE-SLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WYH +L+RV+AE L+R +GAFLVR S H Y++S ++ H RI + + L
Sbjct: 619 WYHSSLSRVQAEHMLMRVPRDGAFLVR-KRSESHSYAISFRAEGKIKHCRIQQEGRLFML 677
Query: 624 GGASTAFPSVPALMRHY 640
G+S F S+ L+ +Y
Sbjct: 678 -GSSAEFESLVDLVNYY 693
Score = 42.3 bits (95), Expect = 0.040
Identities = 41/111 (36%), Positives = 53/111 (47%), Gaps = 17/111 (15%)
Query: 565 WYHGTLA-----RVEAESLLRD-----ADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI 614
W+HG L R AE LL+D A +G FLVR SE+ DY+LS + H RI
Sbjct: 502 WFHGKLGGGRDGRQVAEKLLQDYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRI 561
Query: 615 -CRGAEGYT--LGGASTAFPSVPALMRHYVTAQRLPVRGAE-HMALSTPLP 661
R G T + F S+ LM HY + P+R E M L +P+P
Sbjct: 562 HSRQESGSTRFYLTDNLVFDSLYRLMCHY---RDTPLRCNEFEMRLGSPVP 609
>UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN
full-length enriched library, clone:9930020J04
product:similar to epidermal growth factor-receptor-
binding protein GRB-4; n=5; Eutheria|Rep: Adult female
vagina cDNA, RIKEN full-length enriched library,
clone:9930020J04 product:similar to epidermal growth
factor-receptor- binding protein GRB-4 - Mus musculus
(Mouse)
Length = 123
Score = 52.4 bits (120), Expect = 4e-05
Identities = 34/103 (33%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
Query: 544 LGPIAPPRDLVDATLPLDRQG--WYHGTLARVEAESLLRD-ADEGAFLVRNSESAKHDYS 600
L P P D + +L G WY+G + R +AE L + EG FL+R+SES+ +D+S
Sbjct: 5 LEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFS 64
Query: 601 LSLKSTRGFMHMRICRGAEGYTLGGASTAFPSVPALMRHYVTA 643
+SLK+ H ++ Y +G F ++ L+ HY A
Sbjct: 65 VSLKAQGKNKHFKVQLKETVYCIG--QRKFSTMEELVEHYKKA 105
>UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma
mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 52.4 bits (120), Expect = 4e-05
Identities = 28/67 (41%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLR--DADEGAFLVRNSESAKHDYSLSLKSTR 607
P++ + A L+ WY G L R+EAE L+ D G+FLVR SES +YSLS++
Sbjct: 207 PKNHLAAVTSLESNEWYFGELKRIEAEHYLQLPGNDHGSFLVRISESQSSEYSLSVREEN 266
Query: 608 GFMHMRI 614
H RI
Sbjct: 267 TVKHYRI 273
>UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;
n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase
corkscrew - Drosophila melanogaster (Fruit fly)
Length = 845
Score = 52.4 bits (120), Expect = 4e-05
Identities = 28/97 (28%), Positives = 53/97 (54%), Gaps = 2/97 (2%)
Query: 565 WYHGTLARVEAESLLRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
W+H T++ +EAE LL++ +G+FL R S S ++LS++ H++I + + L
Sbjct: 6 WFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNGDFFDL 65
Query: 624 GGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
G F ++P L+++Y+ L + + + L PL
Sbjct: 66 YGGE-KFATLPELVQYYMENGELKEKNGQAIELKQPL 101
Score = 49.6 bits (113), Expect = 3e-04
Identities = 27/77 (35%), Positives = 45/77 (58%), Gaps = 2/77 (2%)
Query: 565 WYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
W+HG L+ EAE L+ + + G+FLVR S+S D+ LS+++ H+ I + Y +
Sbjct: 111 WFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDKKYDV 170
Query: 624 GGASTAFPSVPALMRHY 640
GG +F ++ L+ HY
Sbjct: 171 GGGE-SFGTLSELIDHY 186
>UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 475
Score = 52.0 bits (119), Expect = 5e-05
Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 10/116 (8%)
Query: 556 ATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI- 614
+T L Q WYHG L R E LL +G FLVR+S ++ DY L+ MH +I
Sbjct: 18 STEDLRSQAWYHGQLQREATEQLL--GRDGEFLVRDSSTSAGDYVLTCMWKNQPMHFKII 75
Query: 615 ---CRGAEGYT---LGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPAVL 664
R +GYT + F ++PAL+R +V +R P+ + + P+ L
Sbjct: 76 RITLRPKQGYTRELFQFENDQFDNIPALIRFHVGGRR-PISHSTGAVIFQPITRTL 130
>UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=28;
Euteleostomi|Rep: Novel SH2 domain-containing protein -
Homo sapiens (Human)
Length = 431
Score = 51.6 bits (118), Expect = 7e-05
Identities = 25/61 (40%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
W+HG ++R +AE+LL + EGAFLVR SE Y+LS + +GF H + + Y+
Sbjct: 325 WFHGIISREDAEALLENMTEGAFLVRVSEKI-WGYTLSYRLQKGFKHFLVDASGDFYSFL 383
Query: 625 G 625
G
Sbjct: 384 G 384
>UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17;
Amniota|Rep: Tyrosine-protein kinase Srms - Homo sapiens
(Human)
Length = 488
Score = 51.6 bits (118), Expect = 7e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 560 LDRQGWYHGTLARVEAESLLRDA--DEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
L Q WY ++R +A+ LL + GAFL+R SES+ YSLS+++ H R+
Sbjct: 115 LSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMA 174
Query: 618 AEGYTLGGASTAFPSVPALMRHY 640
A+G FP + L+ +Y
Sbjct: 175 ADGSLYLQKGRLFPGLEELLTYY 197
>UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Canis lupus familiaris|Rep:
PREDICTED: similar to SH2 domain containing 4B - Canis
familiaris
Length = 488
Score = 51.2 bits (117), Expect = 9e-05
Identities = 25/61 (40%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
W+HG ++R +AE LL + EGAFLVR SE Y+LS + +GF H + + Y+
Sbjct: 382 WFHGIISREDAEDLLENMTEGAFLVRVSEKI-WGYTLSYRLQKGFKHFLVDASGDFYSFL 440
Query: 625 G 625
G
Sbjct: 441 G 441
>UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9;
Endopterygota|Rep: CG3727-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 548
Score = 51.2 bits (117), Expect = 9e-05
Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Query: 563 QGWYHGTLARVEAESLLRD-ADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGY 621
+ WY+G + R + +++L +G FL+R+SE+ DYS+SLK+ H R+ Y
Sbjct: 446 KSWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMY 505
Query: 622 TLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLP 661
+G F S+ L+ HY A + E + L LP
Sbjct: 506 CIG--QRKFHSLDQLVDHYQRAPIYTNKQGEKLYLVRSLP 543
>UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6;
Endopterygota|Rep: CG9209-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 954
Score = 51.2 bits (117), Expect = 9e-05
Identities = 33/98 (33%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
Query: 565 WYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WYHG L R AES LR + + G++LVR S+ Y LS G H RI + +
Sbjct: 84 WYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINHFRITAVCGDFYI 143
Query: 624 GGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLP 661
GG F S+ L+ +Y + L R + ++ P P
Sbjct: 144 GGRQ--FISLSDLVGYYTSCSDLLKRERLAIPVAPPEP 179
Score = 43.6 bits (98), Expect = 0.017
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
W+H + EA +L A G+FLVR S+++ DYSL RI + Y +G
Sbjct: 253 WFHPNCTKNEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 312
Query: 625 GASTAFPSVPALMRHYVTAQRLPVRGAEH 653
G + F + A++ Y Q + H
Sbjct: 313 GRT--FECLDAVINRYRKEQIVEGHSLNH 339
>UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri
tsingtauense|Rep: Bam32 - Branchiostoma belcheri
tsingtauense
Length = 250
Score = 51.2 bits (117), Expect = 9e-05
Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 3/84 (3%)
Query: 558 LPLDRQGWYHGTLARVEAESLL-RDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR 616
L +++ WYHG L+R AE+LL +A++G++L+R+S + +YSLS+K H +I
Sbjct: 7 LEVEQLDWYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGW 66
Query: 617 GAEGYTLGGASTAFPSVPALMRHY 640
+ Y G F S+ + H+
Sbjct: 67 DGKQYQFG--MGVFQSLQEFVEHF 88
>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG18247-PA - Tribolium castaneum
Length = 725
Score = 50.8 bits (116), Expect = 1e-04
Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 565 WYHGTLARVEAESLLRDAD--EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE-GY 621
WYHG L+R E+LL++ +G+FLVR S S+ D+ LS+ H +I R +E +
Sbjct: 9 WYHGKLSREATENLLKEEGRPDGSFLVRESNSSTGDFVLSVLHNNEVSHFQIRRHSEDAF 68
Query: 622 TLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
+T + +L+ HYV + + +E ++L+ P+
Sbjct: 69 FSIDENTKIHGLESLIEHYVNTKGIL---SEGLSLTVPV 104
Score = 35.5 bits (78), Expect = 4.6
Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Query: 562 RQGWYHGTLARVEAESLLR--DADEGAFLVRNSESAK 596
R WYHGTL R EAE+ ++ +G FLVR S+ K
Sbjct: 283 RSYWYHGTLDRHEAETTIKQFSTKDGTFLVRWSDRNK 319
>UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4200-PA - Tribolium castaneum
Length = 1233
Score = 50.4 bits (115), Expect = 2e-04
Identities = 27/81 (33%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Query: 561 DRQGWYHGTLARVEAESLLRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
+ + WYH +++A+ +LR EGAFLVR SE+ + Y++S ++ + H RI
Sbjct: 683 ETEEWYHKHTGKMQADEILRRVKMEGAFLVRPSENDANCYTISFRADKKIKHCRIKLEGR 742
Query: 620 GYTLGGASTAFPSVPALMRHY 640
YT+G + F S+ L+ +Y
Sbjct: 743 LYTIG--NVEFESLVELINYY 761
Score = 35.9 bits (79), Expect = 3.5
Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 12/106 (11%)
Query: 565 WYHGTLA--RVEAESLLR---DADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI-CRGA 618
W+HG LA R EAE LL+ +G FLVR S + +Y LS H RI +
Sbjct: 575 WFHGKLANGREEAEQLLKAYSHLGDGTFLVRASVTFVGEYCLSFWRNGQVNHCRIRSKPD 634
Query: 619 EGYTLGGASTA--FPSVPALMRHYVTAQRLPVRGAE-HMALSTPLP 661
+ +T + A F S+ +L+ HY + P+ AE + L P+P
Sbjct: 635 KQHTRYYLTDAKYFDSLYSLITHY---RNCPLVTAEFSITLQEPVP 677
>UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;
n=3; Mammalia|Rep: Growth factor receptor bound protein
2 - Mus musculus (Mouse)
Length = 203
Score = 50.4 bits (115), Expect = 2e-04
Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 565 WYHGTLARVEAESLL-RDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
W+ G + R +AE +L + +GAFL+R SESA D+SLS+K H ++ R G
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAG 116
>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
- Drosophila melanogaster (Fruit fly)
Length = 847
Score = 50.4 bits (115), Expect = 2e-04
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 541 HLNLGP--IAPPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHD 598
H +L P +AP + + L+ W+HG++ R EAE LL+ ++G FLVR S + D
Sbjct: 453 HASLSPTALAPQQGRSRCEVKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGD 512
Query: 599 YSLSLKSTRGFMHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
Y+L + H R+ + E F ++ L+ HY
Sbjct: 513 YTLCVCFQSKVEHYRV-KYLENKLTIDDEEYFENLGQLVAHY 553
>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
Length = 468
Score = 50.4 bits (115), Expect = 2e-04
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
PRD +P+ W+HG ++R AESLL ++G FLVR S DY+L +
Sbjct: 89 PRDASGQLIPMP---WFHGKISRELAESLLMPREDGLFLVRESAHFPGDYTLCVCFQDQV 145
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
H R+ +G G F S+ L++HY
Sbjct: 146 DHYRM-QGKNGKLTIDEEVYFSSLEELVQHY 175
>UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;
n=26; Euteleostomi|Rep: Growth factor receptor-bound
protein 2 - Homo sapiens (Human)
Length = 217
Score = 50.4 bits (115), Expect = 2e-04
Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 565 WYHGTLARVEAESLL-RDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
W+ G + R +AE +L + +GAFL+R SESA D+SLS+K H ++ R G
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAG 116
>UniRef50_UPI0000F1F0F1 Cluster: PREDICTED: hypothetical protein;
n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 213
Score = 50.0 bits (114), Expect = 2e-04
Identities = 32/99 (32%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
L+ GWY G L +A + L A EG FLVR+S + ++LS+++ RG ++RI +
Sbjct: 51 LNTSGWYWGGLTAGDARAALIGAPEGTFLVRDSSHPLYLFTLSVQTWRGPTNIRIEYDSG 110
Query: 620 GYTLGGASTA------FPSVPALMRHYVTAQRLPVRGAE 652
+ L + A F ++P+L+ HY +A+ + AE
Sbjct: 111 RFRLDSSFPARSCLLSFSALPSLVHHYSSARPEEEKKAE 149
>UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3
adaptor protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor protein -
Strongylocentrotus purpuratus
Length = 389
Score = 50.0 bits (114), Expect = 2e-04
Identities = 23/77 (29%), Positives = 43/77 (55%), Gaps = 3/77 (3%)
Query: 565 WYHGTLARVEAESLLR-DADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
W+HG + R ++E +L + G FL+R SE+ D+++S+K+ H ++ R + + +
Sbjct: 291 WFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKAPERVKHFKVTRSDKKFCI 350
Query: 624 GGASTAFPSVPALMRHY 640
G F S+ L+ HY
Sbjct: 351 G--QRKFESLDDLVDHY 365
>UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15
SCAF14667, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 723
Score = 50.0 bits (114), Expect = 2e-04
Identities = 27/102 (26%), Positives = 46/102 (45%)
Query: 561 DRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
D WY G + R +AE +LR +G FL+R S++ K Y+ S+ H + + G
Sbjct: 618 DESTWYVGDIKRSQAEEMLRGTCDGTFLIRESQTQKGSYACSVVVDGDTKHCVVYKTVTG 677
Query: 621 YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPA 662
Y + S+ L+ HY + ++ L+ P+ A
Sbjct: 678 YGFAEPYNLYSSLKDLVLHYKNVSLVQHNDHLNVTLAHPVLA 719
Score = 45.2 bits (102), Expect = 0.006
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSES-AKHDYSLSLKSTRG 608
P + D + L+ WY G ++R E LRD +G FLVR++ S + +Y+L+L+
Sbjct: 347 PSAMTDTSSLLNDAEWYWGEISREEVNEKLRDTPDGTFLVRDASSKLEGEYTLTLRKGGN 406
Query: 609 FMHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
++I Y T F SV L+ HY
Sbjct: 407 NKLIKIYHREGRYGFSEPLT-FLSVVELINHY 437
>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 747
Score = 50.0 bits (114), Expect = 2e-04
Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
L+ W+HG + R EAE+LL+ ++G FLVR S + DY+L + H RI + AE
Sbjct: 373 LNAMPWFHGRIKREEAENLLKPREDGLFLVRESTNFPGDYTLCVCFNEKVEHYRI-KYAE 431
Query: 620 GYTLGGASTAFPSVPALMRHY 640
F ++ L+ HY
Sbjct: 432 NKLTIDDDEYFDNLGQLVEHY 452
>UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia
fluviatilis|Rep: PLC-gammaS - Ephydatia fluviatilis
Length = 1283
Score = 50.0 bits (114), Expect = 2e-04
Identities = 36/88 (40%), Positives = 46/88 (52%), Gaps = 11/88 (12%)
Query: 562 RQGWYHGTLA--RVEAESLLRDADE--GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
++ W+HG LA RV AE LL D + GAFLVR S + DYSLS + H RI
Sbjct: 541 KEKWFHGKLAGGRVAAEKLLTDYKDVNGAFLVRESTTFTGDYSLSFVRDGKYNHCRIHTK 600
Query: 618 AEG-----YTLGGASTAFPSVPALMRHY 640
+EG Y + T F S+ L+ HY
Sbjct: 601 SEGGKTRFYLID--QTLFDSIYELIMHY 626
Score = 44.0 bits (99), Expect = 0.013
Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 8/84 (9%)
Query: 563 QGWYHGTLARVEAESLLRDAD-EGAFLVR----NSESAKHDYSLSLKSTRGFMHMRICRG 617
+ W+H L+R EAE +L+ +GAFL+R N+++ + +Y++S ++ H RI
Sbjct: 653 KAWFHENLSRSEAEEMLKKVRMDGAFLIRPSEQNTKAGQKNYAISFRAEGKVKHCRIEVD 712
Query: 618 AEG-YTLGGASTAFPSVPALMRHY 640
G Y +G S F S+ L+++Y
Sbjct: 713 ESGQYCIG--SAIFDSLTELVQYY 734
>UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=27;
Euteleostomi|Rep: Suppressor of cytokine signaling 6 -
Homo sapiens (Human)
Length = 535
Score = 50.0 bits (114), Expect = 2e-04
Identities = 25/62 (40%), Positives = 36/62 (58%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM 612
L + L +QGWY G + R EAE L + +G+FLVR+S ++ SLS +S +H
Sbjct: 372 LTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHT 431
Query: 613 RI 614
RI
Sbjct: 432 RI 433
>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
Caenorhabditis elegans
Length = 1224
Score = 50.0 bits (114), Expect = 2e-04
Identities = 22/65 (33%), Positives = 38/65 (58%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P + + LD+ WYHG ++R ++E++L G+FLVR SE++ Y++S++
Sbjct: 179 PSNFIAPYNSLDKYTWYHGKISRSDSEAILGSGITGSFLVRESETSIGQYTISVRHDGRV 238
Query: 610 MHMRI 614
H RI
Sbjct: 239 FHYRI 243
>UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 520
Score = 49.6 bits (113), Expect = 3e-04
Identities = 38/112 (33%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P D+ T PL + W+HG ++R E E LL +++G FLVR S +AK Y LS
Sbjct: 408 PHDMAPPTNPLYNEEWFHGPMSRKEGEPLL--SNDGDFLVRESTTAKDQYVLSGMQNGTP 465
Query: 610 MHMRICRGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGA-EHMALSTPL 660
H+ + +G + F SV L+ +Y RLP+ A + L TP+
Sbjct: 466 KHLLLV-DPQG-KVRTKDKEFDSVSHLI-NYHRNNRLPIISAGSAVHLKTPV 514
>UniRef50_Q6DEF9 Cluster: Zgc:91868; n=1; Danio rerio|Rep: Zgc:91868
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 201
Score = 49.6 bits (113), Expect = 3e-04
Identities = 26/91 (28%), Positives = 49/91 (53%)
Query: 555 DATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI 614
+ T L+ G+Y G + EA L+ G FL+R+S + ++LS K+ G + +RI
Sbjct: 59 NTTSMLEESGFYWGPMTVEEAHLKLKKESVGTFLIRDSRQSDVFFTLSYKAQNGPVSIRI 118
Query: 615 CRGAEGYTLGGASTAFPSVPALMRHYVTAQR 645
++L G+ +F S+ L+ HY+++ +
Sbjct: 119 NFKNSKFSLTGSKESFDSLFKLLEHYISSPK 149
>UniRef50_Q380D8 Cluster: ENSANGP00000027059; n=2; Culicidae|Rep:
ENSANGP00000027059 - Anopheles gambiae str. PEST
Length = 339
Score = 49.6 bits (113), Expect = 3e-04
Identities = 35/90 (38%), Positives = 45/90 (50%), Gaps = 6/90 (6%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRG----FMHMRICR-GAE 619
WYH L R + LL D G+FLVR S + Y+LSL+ G H I R E
Sbjct: 217 WYHENLPRSLSLQLLADKLPGSFLVRKSTTQPDCYALSLRVPPGSGPRIAHYLIVRTSTE 276
Query: 620 GYTLGGASTAFPSVPALMRHY-VTAQRLPV 648
GY + G F S+ AL+ H+ V + LPV
Sbjct: 277 GYKIKGFQKEFSSLRALIVHHSVMPEALPV 306
>UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;
Theria|Rep: SH2 domain-containing protein 2A - Homo
sapiens (Human)
Length = 389
Score = 49.6 bits (113), Expect = 3e-04
Identities = 37/104 (35%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG-YTL 623
W+HG + R EAE LL +G +LVR SESA + L+ +S H + + +G + +
Sbjct: 95 WFHGFITRREAERLLEPKPQGCYLVRFSESAV-TFVLTYRSRTCCRHFLLAQLRDGRHVV 153
Query: 624 GGASTAFPSVPALMRHYVTAQRLPVRG---AEHMALSTPLPAVL 664
G +A + L+ HY TA L G E +A TP PA L
Sbjct: 154 LGEDSAHARLQDLLLHY-TAHPLSPYGETLTEPLARQTPEPAGL 196
>UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide; n=25;
Euteleostomi|Rep: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide - Homo sapiens
(Human)
Length = 280
Score = 49.6 bits (113), Expect = 3e-04
Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Query: 564 GWYHGTLARVEAES-LLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYT 622
GWYHG L R AE+ LL + +G++L+R+S YSLS+++ H + GY+
Sbjct: 34 GWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHV--EYTGYS 91
Query: 623 LGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLP 661
F S+ ++H+ + M L P P
Sbjct: 92 FKFGFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYP 130
>UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;
n=2; Euteleostomi|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 519
Score = 49.2 bits (112), Expect = 3e-04
Identities = 25/62 (40%), Positives = 36/62 (58%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM 612
L + L +QGWY G + R EAE L + +G+FLVR+S ++ SLS +S +H
Sbjct: 356 LTEELKKLAKQGWYWGPITRWEAEEKLVNLPDGSFLVRDSSDDRYLLSLSFRSQGKTLHT 415
Query: 613 RI 614
RI
Sbjct: 416 RI 417
>UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate
phospholipase C, gamma 2; n=4; Danio rerio|Rep: Novel
protein similar to vertebrate phospholipase C, gamma 2 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 270
Score = 49.2 bits (112), Expect = 3e-04
Identities = 26/73 (35%), Positives = 40/73 (54%), Gaps = 2/73 (2%)
Query: 559 PLDRQGWYHGTLARVEAES-LLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
PL GW++ ++R EAE LLR +GAFL+R + + ++LS++S H +I R
Sbjct: 165 PLHHMGWFYSNMSRAEAEDCLLRIPRDGAFLIR-KRNERDTFALSIRSEGDIKHYKIFRK 223
Query: 618 AEGYTLGGASTAF 630
+ Y L A F
Sbjct: 224 SSKYVLADAYEFF 236
Score = 42.3 bits (95), Expect = 0.040
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 11/87 (12%)
Query: 565 WYHGTLA--RVEAESLLRDADEGA------FLVRNSESAKHDYSLSLKSTRGFMHMRI-C 615
W+HG LA R+ AE LLRD +G FLVR S + +Y +SL + H RI C
Sbjct: 54 WFHGRLAEGRITAEKLLRDYCKGTDGNDETFLVRESNTFIGNYCISLWTRGRIQHYRIFC 113
Query: 616 RGAEGYTLG--GASTAFPSVPALMRHY 640
G+ + + FPS+ AL+ +Y
Sbjct: 114 FPENGHKIFFLKSKECFPSMCALIDYY 140
>UniRef50_O15524 Cluster: Suppressor of cytokine signaling 1; n=15;
Tetrapoda|Rep: Suppressor of cytokine signaling 1 - Homo
sapiens (Human)
Length = 211
Score = 49.2 bits (112), Expect = 3e-04
Identities = 32/95 (33%), Positives = 47/95 (49%)
Query: 551 RDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFM 610
R + A+ LD G+Y G L+ A LR G FLVR+S ++LS+K G
Sbjct: 65 RRITRASALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPT 124
Query: 611 HMRICRGAEGYTLGGASTAFPSVPALMRHYVTAQR 645
+R+ A + L G+ +F + L+ HYV A R
Sbjct: 125 SIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPR 159
>UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11;
Mammalia|Rep: Tyrosine-protein kinase 6 - Homo sapiens
(Human)
Length = 451
Score = 49.2 bits (112), Expect = 3e-04
Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 3/89 (3%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADE--GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
++ + W+ G ++R EA L+ GAFL+R SE DY LS++ T+ H +I R
Sbjct: 73 VESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRR 132
Query: 618 AEGYTLGGASTAFPSVPALMRHYVTAQRL 646
A G + +F S+P L+ +Y AQ L
Sbjct: 133 AGGRLHLNEAVSFLSLPELV-NYHRAQSL 160
>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
tyrosine kinase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to protein tyrosine kinase - Nasonia
vitripennis
Length = 739
Score = 48.8 bits (111), Expect = 5e-04
Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 565 WYHGTLARVEAESLLRD--ADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR-GAEGY 621
W+HG L+R +AESLL + D G FLVR S S+ DY LS+ H +I + G + +
Sbjct: 9 WFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAHYQIRKHGEDAF 68
Query: 622 TLGGASTAFPSVPALMRHY-------VTAQRLPVRG 650
T + L+ +Y VT + P+RG
Sbjct: 69 FSIDDETTIHGLETLIEYYQKENDRLVTILQTPIRG 104
Score = 37.9 bits (84), Expect = 0.86
Identities = 21/36 (58%), Positives = 28/36 (77%), Gaps = 4/36 (11%)
Query: 565 WYHGTLARVEAESLL-RDAD-EGAFLVRNSESAKHD 598
WYHGTL R+EA +LL ++ D +G+FLVR SE +HD
Sbjct: 283 WYHGTLDRMEAINLLHKNGDLDGSFLVRLSE--RHD 316
>UniRef50_UPI0000DB7263 Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 6 (SOCS-6) (Suppressor of cytokine
signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4)
(CIS-4); n=1; Apis mellifera|Rep: PREDICTED: similar to
Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor
of cytokine signaling 4) (SOCS-4) (Cytokine-inducible
SH2 protein 4) (CIS-4) - Apis mellifera
Length = 358
Score = 48.8 bits (111), Expect = 5e-04
Identities = 44/187 (23%), Positives = 81/187 (43%), Gaps = 4/187 (2%)
Query: 431 NAFINFKNSNTGEERKNDDVDLSDLPFDMPKLXXXXXXXXXDLRTLPFDMPKLRRKLRGQ 490
+A N K++ + EE ++ D+ + L D R + D + KL
Sbjct: 71 SAVQNNKSTISIEENNVSELKCEDILKNSDILNKDLNKIIKDYRDIE-DYRDIEEKLEDI 129
Query: 491 SLQLNDEFGGGISNASSSQSVEDL--NQGNKLKSSLKLNFDXXXXXXXXKGLHLNLGPIA 548
+ Q+ ++F I++ + S N+ +L+S ++ N + N
Sbjct: 130 NKQITNKFRTDINHENISNIFRSCSSNKIEQLESIIENNEITHHIQRITESTETNRNNDN 189
Query: 549 PPR-DLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTR 607
+ L + L L GWY G ++ EA++ L +GAFLVR+S ++ +LS KS+
Sbjct: 190 KIKASLTEELLKLSNYGWYWGPISGNEADAKLLSEPDGAFLVRDSSDDRYVLTLSFKSSG 249
Query: 608 GFMHMRI 614
+H R+
Sbjct: 250 KLLHARM 256
>UniRef50_Q4RXL6 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
SCAF14979, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 243
Score = 48.8 bits (111), Expect = 5e-04
Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 6/109 (5%)
Query: 545 GPIAPPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
GP R + L+ GWY G + EA+ L EG FL+R+S KH +LS++
Sbjct: 45 GPSEDHRSITTTFQYLETSGWYWGPTSVSEAQEALMKKPEGTFLMRDSSHPKHMLTLSVQ 104
Query: 605 STRGFMHMRI--CRGA---EGYTLGGAST-AFPSVPALMRHYVTAQRLP 647
+ G +R+ RG+ + G T FP V +L++ Y ++ +P
Sbjct: 105 TCCGPTSVRVDYSRGSFWLDSIAAGQPCTQTFPDVLSLVQFYASSGPVP 153
>UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory
subunit 3 (P55, gamma) (Phosphoinositide-3-kinase,
regulatory subunit 3 (P55, gamma), isoform CRA_b); n=17;
Eutheria|Rep: Phosphoinositide-3-kinase, regulatory
subunit 3 (P55, gamma) (Phosphoinositide-3-kinase,
regulatory subunit 3 (P55, gamma), isoform CRA_b) - Homo
sapiens (Human)
Length = 402
Score = 48.8 bits (111), Expect = 5e-04
Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Query: 548 APPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRN-SESAKHDYSLSLKST 606
A P + D+++ L WY G ++R E LRD +G FLVR+ S + DY+L+L+
Sbjct: 48 AVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKG 107
Query: 607 RGFMHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
++I Y T F SV L+ HY
Sbjct: 108 GNNKLIKIYHRDGKYGFSDPLT-FNSVVELINHY 140
Score = 47.6 bits (108), Expect = 0.001
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 2/109 (1%)
Query: 555 DATLP-LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMR 613
D LP D + W+ + RV+AE LL +GAFL+R S S K Y+ S+ + H
Sbjct: 288 DENLPHYDEKTWFVEDINRVQAEDLLYGKPDGAFLIRES-SKKGCYACSVVADGEVKHCV 346
Query: 614 ICRGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPA 662
I A GY + S+ L+ HY + + ++ L+ P+ A
Sbjct: 347 IYSTARGYGFAEPYNLYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHA 395
>UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;
Eutheria|Rep: SH2 domain-containing protein 3A - Homo
sapiens (Human)
Length = 576
Score = 48.8 bits (111), Expect = 5e-04
Identities = 36/105 (34%), Positives = 53/105 (50%), Gaps = 10/105 (9%)
Query: 563 QGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYT 622
Q WYHG L+R +AE+LL+ G FLVR S S + +S + +H + R A
Sbjct: 13 QPWYHGLLSRQKAEALLQ--QNGDFLVRASGSRGGNPVISCRWRGSALHFEVFRVALRPR 70
Query: 623 LGGAST-------AFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
G + FPS+PAL+ Y+T +R P+ A +S P+
Sbjct: 71 PGRPTALFQLEDEQFPSIPALVHSYMTGRR-PLSQATGAVVSRPV 114
>UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase BLK - Homo
sapiens (Human)
Length = 505
Score = 48.8 bits (111), Expect = 5e-04
Identities = 36/98 (36%), Positives = 55/98 (56%), Gaps = 8/98 (8%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAE-SLLRDADE-GAFLVRNSESAKHDYSLSLK--S 605
P + V L+ + W+ + R EAE LL ++ G+FL+R SE+ K +SLS+K +
Sbjct: 109 PSNFVARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVT 168
Query: 606 TRG--FMHMRI-CRGAEGYTLGGASTAFPSVPALMRHY 640
T+G H +I C GY + T FPS+ AL++HY
Sbjct: 169 TQGELIKHYKIRCLDEGGYYISPRIT-FPSLQALVQHY 205
>UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to
protein-tyrosine phosphatase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
phosphatase - Strongylocentrotus purpuratus
Length = 533
Score = 48.4 bits (110), Expect = 6e-04
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
Query: 565 WYHGTLARVEAESLL-RDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
W+H ++ +EAE LL + +G FL R S+S D++LS++ H++I + + L
Sbjct: 6 WFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTGDFFDL 65
Query: 624 GGASTAFPSVPALMRHYVTAQ-RLPVRGAEHMALSTPL 660
G F ++ L++HY + +L R + + L PL
Sbjct: 66 YGGE-KFATLAELVQHYTEGRNQLKERNGQMIELKYPL 102
Score = 46.0 bits (104), Expect = 0.003
Identities = 28/78 (35%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 565 WYHGTLARVEAE-SLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI-CRGAEGYT 622
W+HG + EAE SL+ G++LVR S S DY LS+++ H+ I C+ + Y
Sbjct: 112 WFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQDTK-YD 170
Query: 623 LGGASTAFPSVPALMRHY 640
+GG F ++ L+ HY
Sbjct: 171 VGGGE-QFETLTDLVDHY 187
>UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF13726,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1377
Score = 48.4 bits (110), Expect = 6e-04
Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Query: 565 WYHGTLARVEAE-SLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WYH +L RV+AE L+R +GAFLVR S + Y++S ++ H RI + + L
Sbjct: 687 WYHSSLTRVQAEHMLMRVPRDGAFLVR-KRSEHNSYAISFRAEGKIKHCRIQQEGRLFML 745
Query: 624 GGASTAFPSVPALMRHY 640
G+S F S+ L+ +Y
Sbjct: 746 -GSSAEFESLMDLVSYY 761
Score = 38.7 bits (86), Expect = 0.49
Identities = 39/111 (35%), Positives = 52/111 (46%), Gaps = 17/111 (15%)
Query: 565 WYHGTLA-----RVEAESLLRD-----ADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI 614
W+HG L R AE LL++ A +G FLVR SE+ DY+LS + H RI
Sbjct: 570 WFHGKLGGGRDGRQVAEKLLQEYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRI 629
Query: 615 -CRGAEGYT--LGGASTAFPSVPALMRHYVTAQRLPVRGAE-HMALSTPLP 661
R G T + F S+ L+ HY + P+R E M L P+P
Sbjct: 630 HSRQESGSTRFYLTDNLVFDSLYRLICHY---RDTPLRCNEFEMRLGNPVP 677
>UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome
shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13
SCAF14566, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1249
Score = 48.4 bits (110), Expect = 6e-04
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
Query: 552 DLVDATLPLDRQGWYHGTLARVEAES-LLRDADEGAFLVRNSESAKHDYSLSLKSTRGFM 610
D V P +GW++ L+R +AE L+R +GAFL+R E ++++ K
Sbjct: 619 DAVPQPSPHLNEGWFYSDLSRGQAEDYLMRIPRDGAFLIRQREGEPDSFAITFKGDGKVK 678
Query: 611 HMRICRGAEGYTLGGASTAFPSVPALMRHY 640
H RI + Y L G +T F S+ L+ ++
Sbjct: 679 HCRIQKEGTRYLL-GTTTYFESLVELVSYF 707
Score = 38.3 bits (85), Expect = 0.65
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 11/87 (12%)
Query: 565 WYHGTL--ARVEAESLLRD------ADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR 616
W+HG + R AE L+ + +G FLVR S+ Y+LS H R+
Sbjct: 517 WFHGHMKDGRQMAERLIYEYCAETGGQDGTFLVRPSDRVVLSYTLSFWRNGRVQHCRVRV 576
Query: 617 GAEG---YTLGGASTAFPSVPALMRHY 640
G +G Y A+ FPS+ +L++HY
Sbjct: 577 GNQGGRPYYFLTANLHFPSLISLIQHY 603
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 48.4 bits (110), Expect = 6e-04
Identities = 24/76 (31%), Positives = 38/76 (50%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
W+HG ++R +AE LL G FLVR S++ DY+L + + R+ R +G
Sbjct: 109 WFHGRISREDAEKLLTPPKNGRFLVRESQNYPGDYTLCVSYDGRVENYRVRRNEKGLVTV 168
Query: 625 GASTAFPSVPALMRHY 640
F ++ L+ HY
Sbjct: 169 DDDEYFDNLIKLVEHY 184
>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
sapiens (Human)
Length = 450
Score = 48.4 bits (110), Expect = 6e-04
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 551 RDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFM 610
R+ V A L W+HG + R +AE LL + G FLVR S + DY+L +
Sbjct: 68 REGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVE 127
Query: 611 HMRICRGAEGYTLGGASTAFPSVPALMRHYVT 642
H RI A ++ F ++ L+ HY +
Sbjct: 128 HYRIMYHASKLSI-DEEVYFENLMQLVEHYTS 158
>UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to
ENSANGP00000021630; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000021630 - Nasonia
vitripennis
Length = 389
Score = 48.0 bits (109), Expect = 8e-04
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTR-----GFMHMRI 614
L R W+ + R +L EGAF+VR S S Y+LSL+ R G H I
Sbjct: 251 LRRAPWFQAGIPREITLEVLSQEPEGAFMVRESTSKPGCYALSLRVPREFQPSGIAHYLI 310
Query: 615 CRGAEGYTLGGASTAFPSVPALMRHY-VTAQRLP 647
R +GY + G + F ++ AL+ H+ V + LP
Sbjct: 311 MRTNKGYKIKGFTKEFTTLTALITHHSVMPELLP 344
>UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=2; Danio rerio|Rep: PREDICTED: similar
to SH2 domain containing 4B - Danio rerio
Length = 266
Score = 48.0 bits (109), Expect = 8e-04
Identities = 24/61 (39%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
W+HG ++R ++E+LL +A G+FLVR SE Y+LS ++ GF H I + Y+
Sbjct: 160 WFHGIISREDSETLLMNAAVGSFLVRVSERI-WGYTLSYRTASGFKHFLIDASGDYYSFL 218
Query: 625 G 625
G
Sbjct: 219 G 219
>UniRef50_UPI0000D56C32 Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2
protein 2) (CIS-2); n=1; Tribolium castaneum|Rep:
PREDICTED: similar to Suppressor of cytokine signaling 2
(SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) -
Tribolium castaneum
Length = 252
Score = 48.0 bits (109), Expect = 8e-04
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM 612
L D L GWY+ L ++ LL+D G FLVRNS + +SLS+++ RG +
Sbjct: 83 LQDIVKALRLSGWYYEGLTFDRSDELLKDTRVGTFLVRNSSDPRFLFSLSVQTDRGPKSV 142
Query: 613 RICRGAEGYTLG------GASTAFPSVPALMRHYVTAQR 645
R+ + L + FP V L++HYV ++
Sbjct: 143 RLFYTNGHFRLDAQPHLQASMPLFPGVIELVQHYVRRRK 181
>UniRef50_O14508 Cluster: Suppressor of cytokine signaling 2; n=26;
Euteleostomi|Rep: Suppressor of cytokine signaling 2 -
Homo sapiens (Human)
Length = 198
Score = 48.0 bits (109), Expect = 8e-04
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 13/121 (10%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM 612
L A L + GWY G++ EA+ L++A EG FL+R+S + + ++S+K++ G ++
Sbjct: 36 LAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNL 95
Query: 613 RICRGAEGYTLGGASTA------FPSVPALMRHYV-------TAQRLPVRGAEHMALSTP 659
RI + L F SV L+ +YV T P G H+ L+ P
Sbjct: 96 RIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKP 155
Query: 660 L 660
L
Sbjct: 156 L 156
>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
Homo sapiens (Human)
Length = 505
Score = 48.0 bits (109), Expect = 8e-04
Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 4/116 (3%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADE--GAFLVRNSESAKHDYSLSLKSTR 607
P + V L + W+ G + R +AE L ++ G+FL+R SES K ++SLS+
Sbjct: 101 PSNYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 608 GFMHMRICRGAEGYTLGGASTAFPSVPALMRHYV-TAQRLPVR-GAEHMALSTPLP 661
H RI R EG F ++ + HY T+ L V+ G + + P P
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAP 216
>UniRef50_UPI0000D5590C Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 6 (SOCS-6) (Suppressor of cytokine
signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4)
(CIS-4); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Suppressor of cytokine signaling 6 (SOCS-6)
(Suppressor of cytokine signaling 4) (SOCS-4)
(Cytokine-inducible SH2 protein 4) (CIS-4) - Tribolium
castaneum
Length = 297
Score = 47.6 bits (108), Expect = 0.001
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 555 DATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI 614
D + L WY G + EAE L+ +G FLVR+S S + +S+S +S MH RI
Sbjct: 137 DEIISLSNCYWYWGPMPTAEAEEKLQFKPDGTFLVRDSGSTNYLFSISFRSVGKTMHARI 196
Query: 615 CRGAEGYTLGGA-STAFPSVPALMR 638
Y L G + F +V L++
Sbjct: 197 EYSRGRYNLCGTYAEGFTTVTELIQ 221
>UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal
transduction protein lnk-realted; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to signal
transduction protein lnk-realted - Nasonia vitripennis
Length = 458
Score = 47.2 bits (107), Expect = 0.001
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 4/90 (4%)
Query: 554 VDATLPLDRQGWYHGTLARVEAESL-LRDADEG--AFLVRNSESAKHDYSLSLKSTRGFM 610
VD + L W+HGTL R +A L L +A EG FLVR SE+ K +Y L+
Sbjct: 259 VDLSSSLREYPWFHGTLPRSDAAQLVLHNATEGHGTFLVRQSETRKGEYVLTFNFQGRAK 318
Query: 611 HMRICRGAEGYTLGGASTAFPSVPALMRHY 640
H+R+ +G+ +FP++ ++ H+
Sbjct: 319 HLRMTLTDQGH-CRVQHLSFPAIYDMLDHF 347
>UniRef50_Q4H2S4 Cluster: Suppressor of cytokine signaling; n=1;
Ciona intestinalis|Rep: Suppressor of cytokine signaling
- Ciona intestinalis (Transparent sea squirt)
Length = 509
Score = 47.2 bits (107), Expect = 0.001
Identities = 24/67 (35%), Positives = 41/67 (61%), Gaps = 3/67 (4%)
Query: 551 RDLVDATLPLDRQGWYHGTLARVEAESLL--RDADEGAFLVRNSESAKHDYSLSLKSTR- 607
++ VD+ L + GWY G ++ +AES+L R +EG FLVR+S+ H +L+++S
Sbjct: 319 QEFVDSLKALKQCGWYWGNMSWEDAESMLAQRPGEEGVFLVRDSQDPLHILTLTIRSVEL 378
Query: 608 GFMHMRI 614
H+R+
Sbjct: 379 SIHHVRV 385
>UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to
Src-like-adaptor 2; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to Src-like-adaptor 2 - Monodelphis
domestica
Length = 310
Score = 46.8 bits (106), Expect = 0.002
Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 7/85 (8%)
Query: 563 QGWYHGTLARVEAESLLRDADE--GAFLVRNSESAKHDYSLSLKSTRG-----FMHMRIC 615
QGW + L R +AE LL G+FL+R S++ + YSLS++ +R H RI
Sbjct: 132 QGWLYEGLNREKAEDLLLLPSNHGGSFLIRESQTRRGAYSLSVRLSRPTSRDVVRHYRIH 191
Query: 616 RGAEGYTLGGASTAFPSVPALMRHY 640
R G+ FPS+ AL+ HY
Sbjct: 192 RLENGWFYISPRLTFPSLQALVEHY 216
>UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3;
Gallus gallus|Rep: Putative uncharacterized protein -
Gallus gallus (Chicken)
Length = 431
Score = 46.8 bits (106), Expect = 0.002
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 565 WYHGTLARVEAESLLRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
W+H ++ +EAE LL G+FL R S+S D++LS++ H++I + Y L
Sbjct: 4 WFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNTGDYYDL 63
Query: 624 GGASTAFPSVPALMRHYVTAQRL 646
G F P L+++Y Q L
Sbjct: 64 YGGE-KFARKPELVQYYTEQQGL 85
Score = 39.9 bits (89), Expect = 0.21
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 565 WYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSL 603
WYHG L EAE LL + + G+FLVR S+S D+ LS+
Sbjct: 110 WYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSV 149
>UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p -
Drosophila melanogaster (Fruit fly)
Length = 723
Score = 46.8 bits (106), Expect = 0.002
Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Query: 552 DLVDATLPLDRQGWYHGTLARVEAESLLRDAD---EGAFLVRNSESAKHDYSLSLKSTRG 608
D+ D T + W+HGTL R EA ++ +D G FLVR SE+ + ++ L+
Sbjct: 429 DVADLTAEMSVFPWFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTFNFQGR 488
Query: 609 FMHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
H+R+ +G FPS+ ++ H+
Sbjct: 489 AKHLRLTISEKG-QCRVQHLWFPSIQEMLEHF 519
>UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor
type 11; n=73; Bilateria|Rep: Tyrosine-protein
phosphatase non-receptor type 11 - Homo sapiens (Human)
Length = 597
Score = 46.8 bits (106), Expect = 0.002
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
Query: 565 WYHGTLARVEAESLLRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
W+H + VEAE+LL +G+FL R S+S D++LS++ H++I + Y L
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65
Query: 624 GGASTAFPSVPALMRHYVTAQ-RLPVRGAEHMALSTPL 660
G F ++ L+++Y+ +L + + + L PL
Sbjct: 66 YGGE-KFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 102
Score = 39.9 bits (89), Expect = 0.21
Identities = 22/60 (36%), Positives = 37/60 (61%), Gaps = 6/60 (10%)
Query: 552 DLVDATLPLD-----RQGWYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKS 605
D+++ PL+ + W+HG L+ EAE LL + + G+FLVR S+S D+ LS+++
Sbjct: 94 DVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRT 153
>UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452;
n=1; Danio rerio|Rep: hypothetical protein LOC550452 -
Danio rerio
Length = 250
Score = 46.4 bits (105), Expect = 0.002
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P++ VD +P W+ + +R AE L + GAFL+R S+S+ D+S+S++
Sbjct: 47 PKNYVDRQIP----SWFKESASRGSAEETLMSREVGAFLIRGSQSSPGDFSISVRHDYDV 102
Query: 610 MHMRICRGAEGY 621
H ++ + G+
Sbjct: 103 QHFKVMKDKSGH 114
>UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A1C31 UniRef100 entry -
Xenopus tropicalis
Length = 419
Score = 46.4 bits (105), Expect = 0.002
Identities = 36/94 (38%), Positives = 46/94 (48%), Gaps = 10/94 (10%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF-MHMRICRGA 618
L WYHG L R +AE LL G FL+R+S S+ DY LS G +H +I A
Sbjct: 10 LRSHAWYHGPLPRQDAERLL--VSNGDFLIRDSISSPGDYVLSCFCAGGQPLHFKIIAVA 67
Query: 619 EGYTLGGAST-------AFPSVPALMRHYVTAQR 645
G A T F ++PAL+R YV +R
Sbjct: 68 LRPRRGIARTLYQLEQDQFDNIPALVRSYVGDRR 101
>UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A1C30 UniRef100 entry -
Xenopus tropicalis
Length = 514
Score = 46.4 bits (105), Expect = 0.002
Identities = 36/94 (38%), Positives = 46/94 (48%), Gaps = 10/94 (10%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF-MHMRICRGA 618
L WYHG L R +AE LL G FL+R+S S+ DY LS G +H +I A
Sbjct: 23 LRSHAWYHGPLPRQDAERLL--VSNGDFLIRDSISSPGDYVLSCFCAGGQPLHFKIIAVA 80
Query: 619 EGYTLGGAST-------AFPSVPALMRHYVTAQR 645
G A T F ++PAL+R YV +R
Sbjct: 81 LRPRRGIARTLYQLEQDQFDNIPALVRSYVGDRR 114
>UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3;
Euteleostomi|Rep: Crk-like protein. - Takifugu rubripes
Length = 314
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 561 DRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
DR WY G ++R EA++ L+ G FLVR+S + DY LS+ H I
Sbjct: 10 DRSAWYFGPVSRHEAQNRLQGQKHGIFLVRDSSTCHGDYVLSVSENSKVSHY-IINSLPN 68
Query: 621 YTLGGASTAFPSVPALMRHY 640
F +PAL+ Y
Sbjct: 69 KRFKIGDREFEHLPALLEFY 88
>UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep:
Zgc:112091 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 284
Score = 46.4 bits (105), Expect = 0.002
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
P++ VD +P W+ + +R AE L + GAFL+R S+S+ D+S+S++
Sbjct: 47 PKNYVDRQIP----SWFKESASRGSAEETLMSREVGAFLIRGSQSSPGDFSISVRHDYDV 102
Query: 610 MHMRICRGAEGY 621
H ++ + G+
Sbjct: 103 QHFKVMKDKSGH 114
>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
Caenorhabditis|Rep: C-terminal src kinase protein 1 -
Caenorhabditis elegans
Length = 539
Score = 46.4 bits (105), Expect = 0.002
Identities = 24/80 (30%), Positives = 38/80 (47%)
Query: 561 DRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
+ Q W+H ++R E LLR +G FLVR S + D++L + H RI + + G
Sbjct: 147 NHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGG 206
Query: 621 YTLGGASTAFPSVPALMRHY 640
F ++ L+ HY
Sbjct: 207 QLTCDKEEYFSNLTQLVSHY 226
>UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CSK;
n=1; Hydra vulgaris|Rep: Non-receptor protein-tyrosine
kinase CSK - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 467
Score = 46.4 bits (105), Expect = 0.002
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Query: 558 LPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSL---SLKSTRGFMHMRI 614
L L W+ G + R +AE LL + G FLVR S + DY+L S ++ + H R+
Sbjct: 85 LHLHEMPWFFGKITREKAEELLTPREVGLFLVRESTNFPGDYTLCVVSPQNNKKVEHYRV 144
Query: 615 CRGAEGYTLGGASTAFPSVPALMRHY 640
++ FP++ L++HY
Sbjct: 145 ISTSDNQVTVDEEAFFPTLIELIKHY 170
>UniRef50_UPI0000F1D282 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 186
Score = 46.0 bits (104), Expect = 0.003
Identities = 25/90 (27%), Positives = 46/90 (51%)
Query: 556 ATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRIC 615
A + L G+Y G L EA + L + G FL+R+S A ++LS ++ G +R+
Sbjct: 45 AVVYLTHSGFYWGPLDVDEAHARLANLPLGTFLIRDSMQANVFFTLSYRAPEGPTSVRVL 104
Query: 616 RGAEGYTLGGASTAFPSVPALMRHYVTAQR 645
E ++L G+ F + L+ +Y+ + +
Sbjct: 105 LKNESFSLAGSKHTFSCIFGLLGYYIASPK 134
>UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus
norvegicus|Rep: SH2B adapter protein 3 - Rattus
norvegicus (Rat)
Length = 368
Score = 46.0 bits (104), Expect = 0.003
Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 565 WYHGTLARVEAESL--LRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGY 621
W+HG ++RV A L L+ D G FLVR SES + +Y L+ H+R+ G
Sbjct: 119 WFHGPISRVRAAQLVQLQGPDAHGVFLVRQSESRRGEYVLTFNLQGRAKHLRLVLTERG- 177
Query: 622 TLGGASTAFPSVPALMRHYVTAQRLPV 648
FPSV ++RH+ QR P+
Sbjct: 178 QCRVQHLHFPSVVDMLRHF---QRSPI 201
>UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to SH2 domain containing 4B - Tribolium
castaneum
Length = 412
Score = 45.6 bits (103), Expect = 0.004
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 563 QGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYT 622
+ W+HG + R EAE LL D G+FLVR SE Y++S ++ H + G +
Sbjct: 307 ESWFHGLITRSEAEKLLLDRPYGSFLVRLSERI-WGYAISYRAKEKCKHYLVSAGLKYQF 365
Query: 623 LGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPA 662
LG ++ L+ ++ + P+ G E + + P A
Sbjct: 366 LGNNQIEHETLRDLIEYH---RVHPLTGGEKLVEACPRSA 402
>UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5;
Euteleostomi|Rep: Sh2d3c-prov protein - Xenopus laevis
(African clawed frog)
Length = 676
Score = 45.6 bits (103), Expect = 0.004
Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 10/103 (9%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI----CRGAEG 620
WYHG + R +ESL++ G FL+R+S ++ DY L+ + +H +I + ++
Sbjct: 39 WYHGRIPREVSESLVQ--RNGDFLIRDSLTSLGDYVLTCRWKNESLHFKINKVMVKTSDS 96
Query: 621 YT---LGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
YT +F ++PAL+R+YV ++R PV + P+
Sbjct: 97 YTRIQYLFEQESFDNIPALVRYYVGSRR-PVSEQSSAMIYCPI 138
>UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1
SCAF15008, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 968
Score = 45.6 bits (103), Expect = 0.004
Identities = 25/57 (43%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 565 WYHGTLARVEAESLL-RDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
WYH ++RV+AE LL R +G++LVR+SES Y+L L R RI A+G
Sbjct: 14 WYHRDISRVQAEELLARAGKDGSYLVRDSESVPGAYALCLLFQRHVHTYRILPDADG 70
>UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep:
CG32406-PA - Drosophila melanogaster (Fruit fly)
Length = 474
Score = 45.6 bits (103), Expect = 0.004
Identities = 32/89 (35%), Positives = 45/89 (50%), Gaps = 5/89 (5%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK--STRG--FMHMRICRGAEG 620
WY ++R A +L+ GAFLVR S S Y+L+L+ S G + I R G
Sbjct: 342 WYQAGISRDIAVEVLQSKSPGAFLVRKSSSKPGCYALTLRVPSPPGPKIANYIILRSPRG 401
Query: 621 YTLGGASTAFPSVPALMRHY-VTAQRLPV 648
Y + G F S+ AL+ H+ V + LPV
Sbjct: 402 YKIKGFRKEFSSLKALITHHSVMPELLPV 430
>UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60
protein - Drosophila melanogaster (Fruit fly)
Length = 506
Score = 45.6 bits (103), Expect = 0.004
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Query: 540 LHLNLGPIAPPRDLVDATLPLDRQG-WYHGTLARVEAESLLRDADEGAFLVRNSESAKHD 598
LH + P LVD R WY G ++R EA+S+L +G+FLVR++ S K +
Sbjct: 6 LHYSTMRPQAPGSLVDPNEDELRMAPWYWGRISREEAKSILHGKPDGSFLVRDALSMKGE 65
Query: 599 YSLSLKSTRGFMHMRICRGAEGYTLGGAST-AFPSVPALMRHY 640
Y+L+L ++IC Y G T F SV ++ +Y
Sbjct: 66 YTLTLMKDGCEKLIKICHMDRKY--GFIETDLFNSVVEMINYY 106
Score = 35.5 bits (78), Expect = 4.6
Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
W R AE +L+ A G FL+R + A H Y+LS+ H I + G+
Sbjct: 337 WLLKDAKRRNAEEMLKGAPSGTFLIR-ARDAGH-YALSIACKNIVQHCLIYETSTGFGFA 394
Query: 625 GASTAFPSVPALMRHY 640
+ ++ +L+ HY
Sbjct: 395 APYNIYATLKSLVEHY 410
>UniRef50_Q45FX5 Cluster: Protein vav-1; n=4; Caenorhabditis|Rep:
Protein vav-1 - Caenorhabditis elegans
Length = 1007
Score = 45.6 bits (103), Expect = 0.004
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
WY G + R +AES L+ G FLVR S++ K ++SL HM I + ++G
Sbjct: 831 WYMGEMERAKAESTLKGTPNGTFLVRYSKNRKQT-AISLSYKNDVKHMIIEQNSDGKVYL 889
Query: 625 GASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTP 659
F S L+++Y + + + A L P
Sbjct: 890 DEDYIFNSTVELVQYYRSNNLIEIFAALDTCLKNP 924
>UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 2B; n=6; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
2B - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1226
Score = 45.6 bits (103), Expect = 0.004
Identities = 26/57 (45%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 565 WYHGTLARVEAESLLRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
WYH ++RV AE LL A +G+FLVR+SES Y+L L R RI A+G
Sbjct: 6 WYHRDISRVRAEELLAHAGIDGSFLVRDSESVPGAYALCLLFQRHVHTYRILPDADG 62
>UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2;
Sophophora|Rep: Tyrosine-protein kinase shark -
Drosophila melanogaster (Fruit fly)
Length = 939
Score = 45.6 bits (103), Expect = 0.004
Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 561 DRQGWYHGTLARVEAESLLRDA-DEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR 616
D WYHG L+R A+ LL+ ++G FLVR S +A D+ LSL H ++ R
Sbjct: 6 DPMKWYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQVRR 62
>UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor
type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase
non-receptor type 6 - Homo sapiens (Human)
Length = 595
Score = 45.6 bits (103), Expect = 0.004
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Query: 565 WYHGTLARVEAESLLRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
W+H L+ ++AE+LL+ G+FL R S + D+SLS++ H+RI + Y L
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63
Query: 624 GGASTAFPSVPALMRHYVTAQ 644
G F ++ L+ +Y Q
Sbjct: 64 YGGE-KFATLTELVEYYTQQQ 83
Score = 41.1 bits (92), Expect = 0.092
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 13/87 (14%)
Query: 565 WYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTR---------GFMHMRI 614
WYHG ++ +AE+LL+ E FLVR S S D+ LS+ S + H+++
Sbjct: 110 WYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKV 169
Query: 615 -CRGAEGYTLGGASTAFPSVPALMRHY 640
C G YT+GG T F S+ L+ H+
Sbjct: 170 MCEGGR-YTVGGLET-FDSLTDLVEHF 194
>UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CRK
protein - Nasonia vitripennis
Length = 298
Score = 45.2 bits (102), Expect = 0.006
Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 7/85 (8%)
Query: 561 DRQGWYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
D+ WY G ++R +A LL E G FLVR+S S + D+ L ++ H I + +
Sbjct: 9 DKSSWYFGAMSRQDASDLLMSEKEGGVFLVRDSISIQGDFVLCVREDSKVSHYIINKIQQ 68
Query: 620 G----YTLGGASTAFPSVPALMRHY 640
G Y +G FP +P L+ Y
Sbjct: 69 GDQIRYRIG--DQIFPDIPNLLAFY 91
>UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65942
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 249
Score = 45.2 bits (102), Expect = 0.006
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 7/92 (7%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
PR+ + T P WY +R A+ L GAF++R S+S+ D+S+S++
Sbjct: 47 PRNYIVTTFP----SWYKENTSRQSAQDELMCQPIGAFIIRGSQSSPGDFSISVRHENDV 102
Query: 610 MHMRICRGAEG-YTLGGASTAFPSVPALMRHY 640
H ++ R +G Y L S F S+ L+ +Y
Sbjct: 103 QHFKVMRDRQGRYYLW--SEMFTSLNKLVDYY 132
>UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio
rerio|Rep: SH2 domain containing 3C - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 635
Score = 45.2 bits (102), Expect = 0.006
Identities = 34/102 (33%), Positives = 52/102 (50%), Gaps = 9/102 (8%)
Query: 551 RDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFM 610
++L ++ L GWYHG + +ESL++ EG FL+R+S S+ DY L+ + + +
Sbjct: 36 KELKLSSCNLSSHGWYHGRIPWEVSESLVQQ--EGDFLIRDSLSSIGDYVLTCRWNQKAL 93
Query: 611 HMRI----CRGAEGYTLGG---ASTAFPSVPALMRHYVTAQR 645
H I R + YT F SVPAL+ YV +R
Sbjct: 94 HFLITKVLLRSYDTYTRVQYILEEETFYSVPALVHSYVGNKR 135
>UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted;
n=2; Endopterygota|Rep: Signal transduction protein
lnk-realted - Aedes aegypti (Yellowfever mosquito)
Length = 564
Score = 45.2 bits (102), Expect = 0.006
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 555 DATLPLDRQGWYHGTLARVEAESLLRD---ADEGAFLVRNSESAKHDYSLSLKSTRGFMH 611
D T + W+HGTLAR EA L+ + G FLVR SE+ K ++ L+ H
Sbjct: 409 DLTAMMREYPWFHGTLARSEAAQLVLHNGLSSHGVFLVRQSETRKGEFVLTFNFQGKAKH 468
Query: 612 MRICRGAEGYTLGGASTAFPSVPALMRHY 640
+R+ G FPS+ ++ H+
Sbjct: 469 LRMTLNDLG-QCRVQHLWFPSITEMLEHF 496
>UniRef50_Q16U30 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 341
Score = 45.2 bits (102), Expect = 0.006
Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK-STRG--FMHMRICR 616
LD W+ L R + +L GAFLVR S + + ++LSL+ + G +H I +
Sbjct: 211 LDSASWFQAGLPREISLEVLTQQAPGAFLVRRSTTKQGCFALSLRVPSPGPKVVHYLILK 270
Query: 617 GAEGYTLGGASTAFPSVPALMRHY-VTAQRLPV 648
GY + G + F S+ AL+ H+ V + LPV
Sbjct: 271 TERGYKIKGFTKEFSSLRALITHHSVMPEMLPV 303
>UniRef50_A7SGW3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 169
Score = 45.2 bits (102), Expect = 0.006
Identities = 24/64 (37%), Positives = 34/64 (53%)
Query: 551 RDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFM 610
R L + L GWY G ++ EAE L + +G FLVR+SE+ H S+S +S
Sbjct: 15 RRLSSSLKTLSNCGWYWGPMSSKEAEKELYNQPDGCFLVRDSENDYHLLSVSFRSKGATC 74
Query: 611 HMRI 614
H R+
Sbjct: 75 HTRL 78
>UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|Rep:
Phospholipase C gamma - Chaetopterus pergamentaceus
Length = 1322
Score = 45.2 bits (102), Expect = 0.006
Identities = 38/107 (35%), Positives = 54/107 (50%), Gaps = 14/107 (13%)
Query: 565 WYHGTL--ARVEAESLLRDAD---EGAFLVRNSESAKHDYSLSLKSTRGFMHMRIC---- 615
W+HG L R +AE LL++ +G FLVR S++ D+SLS H RI
Sbjct: 560 WFHGKLEGGRRKAEDLLKEYSYLGDGTFLVRESDTFVGDFSLSFWRKDSVNHCRIRSKQE 619
Query: 616 RGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAE-HMALSTPLP 661
RG Y L + AF S+ +L+ HY Q+ P+R + L P+P
Sbjct: 620 RGQTKYYLID-NLAFDSLYSLITHY---QKYPLRSQDFQQILKEPVP 662
Score = 44.4 bits (100), Expect = 0.010
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
Query: 565 WYHGTLARVEAESLL-RDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WYH L R AE +L R +GAFLVR + + Y++S ++ H I + +T+
Sbjct: 672 WYHEKLDRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFRAEGKIKHCIIKQEGRLFTI 731
Query: 624 GGASTAFPSVPALMRHY 640
G A F S+ L+ +Y
Sbjct: 732 GNAQ--FESLVELVNYY 746
>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
tyrosine-protein kinase - Homo sapiens (Human)
Length = 507
Score = 45.2 bits (102), Expect = 0.006
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Query: 551 RDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFM 610
R+ + A L W+HG ++ EA L+ ++G FLVR S DY L + R +
Sbjct: 108 REALSADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVI 167
Query: 611 HMRICRGAEGYTLGGASTAFPSVPALMRHY 640
H R+ +G+ + F ++ ++ HY
Sbjct: 168 HYRVLH-RDGHLTIDEAVFFCNLMDMVEHY 196
>UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;
n=3; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 510
Score = 44.8 bits (101), Expect = 0.007
Identities = 34/84 (40%), Positives = 46/84 (54%), Gaps = 7/84 (8%)
Query: 563 QGWYHGTLARVEAESLLR--DADEGAFLVRNSESAKHDYSLSLKS---TRGFMHMRICRG 617
Q WY GTL R E E LL + D GAFLVR+SE Y LS+ S +R H++I +
Sbjct: 121 QPWYFGTLNRFETEILLLAPENDVGAFLVRHSEKDNIGYVLSVLSGDRSREVKHIKIHQN 180
Query: 618 A-EGYTLGGASTAFPSVPALMRHY 640
E + L + T F S+ L+ +Y
Sbjct: 181 QNESFYLDKSQT-FQSLEKLVDYY 203
>UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homolog;
n=5; Clupeocephala|Rep: V-crk sarcoma virus CT10
oncogene homolog - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 311
Score = 44.8 bits (101), Expect = 0.007
Identities = 23/51 (45%), Positives = 28/51 (54%)
Query: 561 DRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMH 611
DR WY G L+R EA SLL+ G FLVR+S + DY LS+ H
Sbjct: 9 DRGSWYWGRLSRQEAVSLLQGQRHGVFLVRDSITIPGDYVLSVSENSKVSH 59
>UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|Rep:
Zgc:158474 protein - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 906
Score = 44.8 bits (101), Expect = 0.007
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 559 PLDRQGWYHGTLARVEAESLLRD---ADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRIC 615
PL W+HGTL+R++A L+ A G FLVR SE+ + +Y L+ H+R+
Sbjct: 709 PLSECQWFHGTLSRLKAAQLVLAGGMASHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLS 768
Query: 616 RGAEG 620
+G
Sbjct: 769 LNEDG 773
>UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10;
Endopterygota|Rep: Tyrosine-protein kinase Btk29A -
Drosophila melanogaster (Fruit fly)
Length = 786
Score = 44.8 bits (101), Expect = 0.007
Identities = 27/59 (45%), Positives = 36/59 (61%), Gaps = 2/59 (3%)
Query: 556 ATLPLDRQGWYHGTLARVEAESLLRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMR 613
A L L+R WY G ++R AESLL+ D EG F+VR S S K Y+LSL + H++
Sbjct: 401 ALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKS-STKGLYTLSLHTKVPQSHVK 458
>UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000022029 - Anopheles gambiae
str. PEST
Length = 1230
Score = 44.4 bits (100), Expect = 0.010
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 565 WYHGTLARVEAESLLRDA-DEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WYH T R ++E +L +GAFLVR SE + +S ++ F H RI Y +
Sbjct: 682 WYHQTTTREQSEIVLNQIPQDGAFLVRPSEKGTKAFVISFRAHGKFKHCRIRVEGRLYEM 741
Query: 624 GGASTAFPSVPALMRHY 640
GG F S+ L+ Y
Sbjct: 742 GGME--FESLVDLVNFY 756
Score = 37.5 bits (83), Expect = 1.1
Identities = 36/109 (33%), Positives = 54/109 (49%), Gaps = 14/109 (12%)
Query: 563 QGWYHGTLA--RVEAESLLRDAD---EGAFLVRNSESAKHDYSLSLKSTRGFMHMRI--- 614
+ W+HG L+ R EAE LL+ +G FLVR S + DY LS H RI
Sbjct: 568 ENWFHGKLSGGREEAEKLLQQFSHLGDGTFLVRESVTFVGDYCLSFWRQGKPNHCRIKLK 627
Query: 615 -CRGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAE-HMALSTPLP 661
+G Y L + F S+ +L+ +Y ++ +R AE ++ L P+P
Sbjct: 628 QDKGVTKYYL-MENVLFESLYSLIMYY---RQNALRSAEFYITLKEPVP 672
>UniRef50_Q90X67 Cluster: Suppressor of cytokine signaling 3; n=13;
Euteleostomi|Rep: Suppressor of cytokine signaling 3 -
Gallus gallus (Chicken)
Length = 209
Score = 44.4 bits (100), Expect = 0.010
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM 612
+V+ L G+Y T+ EA LL G FL+R+S +H ++LS+K+ G ++
Sbjct: 34 VVNTVRKLQESGFYWSTVTGGEANVLLSAEPAGTFLIRDSSDQRHFFTLSVKTESGTKNL 93
Query: 613 RI-CRG 617
RI C G
Sbjct: 94 RIQCEG 99
>UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma-1; n=65; Eumetazoa|Rep:
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma-1 - Homo sapiens (Human)
Length = 1290
Score = 44.4 bits (100), Expect = 0.010
Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 565 WYHGTLARVEAE-SLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WYH +L R +AE L+R +GAFLVR + + Y++S ++ H R+ + EG T+
Sbjct: 668 WYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCRVQQ--EGQTV 724
Query: 624 GGASTAFPSVPALMRHY 640
++ F S+ L+ +Y
Sbjct: 725 MLGNSEFDSLVDLISYY 741
Score = 43.2 bits (97), Expect = 0.023
Identities = 42/127 (33%), Positives = 60/127 (47%), Gaps = 18/127 (14%)
Query: 550 PRDLVDATLPLDRQGWYHGTLA-----RVEAESLLRD------ADEGAFLVRNSESAKHD 598
P+++ +T + W+HG L R AE LL + A +G+FLVR SE+ D
Sbjct: 535 PKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGD 594
Query: 599 YSLSLKSTRGFMHMRICRGAEGYTLGGAST---AFPSVPALMRHYVTAQRLPVRGAE-HM 654
Y+LS H RI + T T F S+ L+ HY Q++P+R E M
Sbjct: 595 YTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY---QQVPLRCNEFEM 651
Query: 655 ALSTPLP 661
LS P+P
Sbjct: 652 RLSEPVP 658
>UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulatory
subunit beta; n=114; Euteleostomi|Rep:
Phosphatidylinositol 3-kinase regulatory subunit beta -
Homo sapiens (Human)
Length = 728
Score = 44.4 bits (100), Expect = 0.010
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 1/102 (0%)
Query: 561 DRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
+ + WY G + R +AE +L +G FL+R S S + Y+ S+ H I R A G
Sbjct: 618 EERTWYVGKINRTQAEEMLSGKRDGTFLIRES-SQRGCYACSVVVDGDTKHCVIYRTATG 676
Query: 621 YTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLPA 662
+ + S+ L+ HY A + A + L+ P+ A
Sbjct: 677 FGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRA 718
Score = 40.7 bits (91), Expect = 0.12
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSES-AKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WY G ++R E LRD +G FLVR++ S + +Y+L+L+ +++ +G+
Sbjct: 330 WYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFH-RDGHYG 388
Query: 624 GGASTAFPSVPALMRHY 640
F SV L+ HY
Sbjct: 389 FSEPLTFCSVVDLINHY 405
>UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adaptor
protein CG3715-PA; n=2; Apocrita|Rep: PREDICTED: similar
to SHC-adaptor protein CG3715-PA - Apis mellifera
Length = 443
Score = 44.0 bits (99), Expect = 0.013
Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 6/103 (5%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
L ++ W+HG+++R EAES+L +G FLVR S+ + Y L+ + H+ + E
Sbjct: 341 LKQEIWFHGSVSRAEAESML--TRDGDFLVRESQGSPGQYVLTGMNNNTPKHLLLI-DPE 397
Query: 620 GYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEH-MALSTPLP 661
G + F SV L+ H+ LP+ A+ + L P+P
Sbjct: 398 G-VVRTKDRVFDSVSHLVNHHCD-NVLPIISADSVLVLRYPIP 438
>UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF10147, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 279
Score = 44.0 bits (99), Expect = 0.013
Identities = 20/39 (51%), Positives = 28/39 (71%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSL 603
W+ G ++R+EAE LR D G FLVR SESA ++S+S+
Sbjct: 60 WFVGRVSRLEAEKRLRWQDPGVFLVRESESAPGEFSVSV 98
>UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14724,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 803
Score = 44.0 bits (99), Expect = 0.013
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 10/96 (10%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGA- 618
L WYHG + R AE+L++ +G FL+R+S S+ Y L+ + H +I +
Sbjct: 31 LRSHAWYHGAIPRQVAENLVQ--RDGDFLIRDSLSSPGSYVLTSQWRNTAQHFKINKKVV 88
Query: 619 ---EGYT---LGGASTAFPSVPALMRHYVTAQRLPV 648
E YT F SVPAL+R YV R PV
Sbjct: 89 ALNEAYTRVEFRLEREGFDSVPALIRFYV-GNRKPV 123
>UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF14993, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1136
Score = 44.0 bits (99), Expect = 0.013
Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 565 WYHGTLARVEAESLLRDA-DEGAFLVRNSESAKHDYSLS-LKSTRGFMHMRICRGAEGYT 622
WYHG L R AE LR A + G++L+R S+ + LS L T H RI Y
Sbjct: 185 WYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLSFLSMTNVVNHFRIIAMCGDYY 244
Query: 623 LGGASTAFPSVPALMRHY 640
+GG F S+ L+ +Y
Sbjct: 245 IGG--RRFSSLSDLIGYY 260
Score = 37.9 bits (84), Expect = 0.86
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 559 PLDRQGWYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
P + + WYHG + + EA +LL + +FLVR S++ DYSL ++ +I
Sbjct: 353 PHEGKVWYHGHITKKEAYNLLMTVGQVCSFLVRPSDNTPGDYSLFFRTNDIIQRFKISPT 412
Query: 618 AEG-YTLGG 625
+ Y +GG
Sbjct: 413 SNNQYMMGG 421
>UniRef50_Q9W4A9 Cluster: CG3208-PA, isoform A; n=5; Diptera|Rep:
CG3208-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 494
Score = 44.0 bits (99), Expect = 0.013
Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
Query: 566 YHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRIC-RGAEGYTLG 624
YHG + +EAE LL +A +G++ VR S + Y+LSL+ + H ++ + G+ L
Sbjct: 83 YHGLMGHLEAEQLLANARDGSYFVRRSPQSDGYYTLSLRFNKRPKHYKLLYKPGVGHYLR 142
Query: 625 GASTAFPSV 633
G F +V
Sbjct: 143 GQDKRFDTV 151
>UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium
discoideum|Rep: SHK1 protein - Dictyostelium discoideum
(Slime mold)
Length = 527
Score = 44.0 bits (99), Expect = 0.013
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLS-LKSTRGFMH 611
++D L W+HG ++ E+E+ LR EG FLVR S S Y++S + G H
Sbjct: 412 ILDKIRQLMECAWFHGDISTSESENRLRQKPEGTFLVRFSTSEYGAYTISKVSKNGGISH 471
Query: 612 MRICR 616
RI R
Sbjct: 472 QRIHR 476
>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
aegypti (Yellowfever mosquito)
Length = 939
Score = 44.0 bits (99), Expect = 0.013
Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Query: 565 WYHGTLARVEAESLLR-DADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR-GAEGYT 622
W+HG ++R AE +LR + G F+VR S S++ D+ LS+ +H +I R G + +
Sbjct: 9 WFHGKISRERAEEILRQEGGNGVFMVRESTSSEGDFVLSVLFQDEVVHYQIRRHGDDAFF 68
Query: 623 LGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLP 661
+ +L+ HY + V + + S P P
Sbjct: 69 SIDDHMPIHGLDSLIEHYRESSNGLVTRLQTVCQSGPPP 107
>UniRef50_O14543 Cluster: Suppressor of cytokine signaling 3; n=21;
Mammalia|Rep: Suppressor of cytokine signaling 3 - Homo
sapiens (Human)
Length = 225
Score = 44.0 bits (99), Expect = 0.013
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM 612
+V+A L G+Y + EA LL G FL+R+S +H ++LS+K+ G ++
Sbjct: 34 VVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNL 93
Query: 613 RI-CRG 617
RI C G
Sbjct: 94 RIQCEG 99
>UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21;
Euteleostomi|Rep: Src-like-adapter 2 - Homo sapiens
(Human)
Length = 261
Score = 44.0 bits (99), Expect = 0.013
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 7/84 (8%)
Query: 564 GWYHGTLARVEAESLLRDADE--GAFLVRNSESAKHDYSLSLKSTR-----GFMHMRICR 616
GW + L+R +AE LL GAFL+R S++ + YSLS++ +R H RI
Sbjct: 93 GWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHC 152
Query: 617 GAEGYTLGGASTAFPSVPALMRHY 640
G+ FPS+ AL+ HY
Sbjct: 153 LDNGWLYISPRLTFPSLQALVDHY 176
>UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50;
Euteleostomi|Rep: Ras GTPase-activating protein 1 - Homo
sapiens (Human)
Length = 1047
Score = 44.0 bits (99), Expect = 0.013
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 554 VDATLPLDRQGWYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTRGFM-H 611
+ T P Q WYHG L R AE LR A + G++L+R S+ + LS S + H
Sbjct: 171 IPLTAPPTNQ-WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNH 229
Query: 612 MRICRGAEGYTLGGASTAFPSVPALMRHY 640
RI Y +GG F S+ L+ +Y
Sbjct: 230 FRIIAMCGDYYIGG--RRFSSLSDLIGYY 256
Score = 42.3 bits (95), Expect = 0.040
Identities = 24/84 (28%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Query: 559 PLDRQGWYHGTLARVEAESLLRDADEG-AFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
P + + W+HG +++ EA +LL + +FLVR S++ DYSL ++ +IC
Sbjct: 345 PHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPT 404
Query: 618 AEG-YTLGGASTAFPSVPALMRHY 640
+ +GG + S+ ++ HY
Sbjct: 405 PNNQFMMGG--RYYNSIGDIIDHY 426
>UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep:
P47(GAG-CRK) protein - Avian sarcoma virus (strain CT10)
Length = 440
Score = 44.0 bits (99), Expect = 0.013
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 561 DRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMH--MRICRGA 618
DR WY G L+R +A SLL+ G FLVR+S S D+ LS+ + H + A
Sbjct: 244 DRGSWYWGRLSRGDAVSLLQGQRHGTFLVRDSGSIPGDFVLSVSESSRVSHYIVNSLGPA 303
Query: 619 EGYTLGGASTAFPSV 633
G GG P +
Sbjct: 304 GGRRAGGEGPGAPGL 318
>UniRef50_UPI0000D559E9 Cluster: PREDICTED: similar to CG8146-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG8146-PA - Tribolium castaneum
Length = 687
Score = 43.6 bits (98), Expect = 0.017
Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 564 GWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
GWY G L AE +L + +G+F+VR+S + +SL+ K H+RI ++
Sbjct: 478 GWYWGPLPSEVAEKILSNEPDGSFIVRDSSDDHYIFSLTFKLNNCVRHVRIDHDQGNFSF 537
Query: 624 GGASTAFPS 632
G+ T F S
Sbjct: 538 -GSCTKFKS 545
>UniRef50_UPI00015A6A53 Cluster: hypothetical protein LOC406311;
n=1; Danio rerio|Rep: hypothetical protein LOC406311 -
Danio rerio
Length = 394
Score = 43.6 bits (98), Expect = 0.017
Identities = 29/81 (35%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
L + W+ G LAR AE LL GAFL+RNS S+K Y+ S+ H I
Sbjct: 287 LREESWFVGDLARGPAEELLLGKPNGAFLIRNS-SSKDCYACSVVVNSQVRHCVIRHTER 345
Query: 620 GYTLGGASTAFPSVPALMRHY 640
GY S+ L+ HY
Sbjct: 346 GYGFVEPFDLHKSLKDLVLHY 366
Score = 36.7 bits (81), Expect = 2.0
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSE-SAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WY ++R E +L +GAFLVR++ + +Y+L++++ +RI EG
Sbjct: 6 WYWADISREEVNEILHGMPDGAFLVRDASCKVQGEYTLTVRNNGTNKLIRILH-QEGKFG 64
Query: 624 GGASTAFPSVPALMRHY 640
F SVP L+ Y
Sbjct: 65 FSEPLTFSSVPELISFY 81
>UniRef50_Q6PBV3 Cluster: Zgc:73230; n=2; Danio rerio|Rep: Zgc:73230
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 321
Score = 43.6 bits (98), Expect = 0.017
Identities = 29/81 (35%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
L + W+ G LAR AE LL GAFL+RNS S+K Y+ S+ H I
Sbjct: 214 LREESWFVGDLARGPAEELLLGKPNGAFLIRNS-SSKDCYACSVVVNSQVRHCVIRHTER 272
Query: 620 GYTLGGASTAFPSVPALMRHY 640
GY S+ L+ HY
Sbjct: 273 GYGFVEPFDLHKSLKDLVLHY 293
Score = 36.7 bits (81), Expect = 2.0
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSE-SAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WY ++R E +L +GAFLVR++ + +Y+L++++ +RI EG
Sbjct: 32 WYWADISREEVNEILHGMPDGAFLVRDASCKVQGEYTLTVRNNGTNKLIRILH-QEGKFG 90
Query: 624 GGASTAFPSVPALMRHY 640
F SVP L+ Y
Sbjct: 91 FSEPLTFSSVPELISFY 107
>UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 573
Score = 43.6 bits (98), Expect = 0.017
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 560 LDRQGWYHGTLARVEAESLLRDAD--EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
L ++ WYHG ++R++AE LL + G+FLVR+S + +Y LSL H I R
Sbjct: 4 LSKELWYHGRISRLDAEQLLDNFGRLSGSFLVRDSLTTTGEYVLSLSFQGKKYHYIISRH 63
Query: 618 AEGYTLGGASTAFPSVPALMRHY 640
+G F S L++++
Sbjct: 64 PDGSVAIQDGAKFDSPIELIQYH 86
>UniRef50_Q9VX18 Cluster: CG8146-PA; n=1; Drosophila
melanogaster|Rep: CG8146-PA - Drosophila melanogaster
(Fruit fly)
Length = 1039
Score = 43.6 bits (98), Expect = 0.017
Identities = 21/61 (34%), Positives = 33/61 (54%)
Query: 564 GWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
GWY G L+ AE +L +G+F+VR+S + +SLS K H+RI + ++
Sbjct: 867 GWYWGPLSSEAAEKVLSSEPDGSFIVRDSSDDHYIFSLSFKLNNCVRHVRIEQDQGTFSF 926
Query: 624 G 624
G
Sbjct: 927 G 927
>UniRef50_Q5BXE5 Cluster: SJCHGC04002 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04002 protein - Schistosoma
japonicum (Blood fluke)
Length = 240
Score = 43.6 bits (98), Expect = 0.017
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 6/94 (6%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK-----STRGFMHMRI 614
L++ WY L R A LL + G+FLVRNS + +LS++ + G H I
Sbjct: 81 LNQAPWYQALLPREIAFELLAREEVGSFLVRNSATHPGCCALSVRVPNKDNPLGITHYLI 140
Query: 615 CRGAEGYTLGGASTAFPSVPALMRHY-VTAQRLP 647
+ ++G L G +PS+ AL+ H V + LP
Sbjct: 141 QKTSQGVRLKGLDKEWPSLQALVTHLTVIPEMLP 174
>UniRef50_Q29G65 Cluster: GA20849-PA; n=1; Drosophila
pseudoobscura|Rep: GA20849-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 891
Score = 43.6 bits (98), Expect = 0.017
Identities = 21/61 (34%), Positives = 34/61 (55%)
Query: 564 GWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
GWY G L+ AE +L + +G+F+VR+S + +SLS K H+RI + ++
Sbjct: 745 GWYWGPLSGEAAEKVLSNEPDGSFIVRDSSDDHYIFSLSFKLNNCVRHVRIEQDQGTFSF 804
Query: 624 G 624
G
Sbjct: 805 G 805
>UniRef50_UPI0000F1F169 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 720
Score = 43.2 bits (97), Expect = 0.023
Identities = 22/55 (40%), Positives = 32/55 (58%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI 614
L+R GWY G + +AE LR +G+FLVR+S ++ SLS +S H R+
Sbjct: 534 LERCGWYWGPMNWEDAEMKLRGKPDGSFLVRDSSDPRYILSLSFRSQGVTHHTRM 588
>UniRef50_UPI0000D555ED Cluster: PREDICTED: similar to CG32406-PA;
n=2; Endopterygota|Rep: PREDICTED: similar to CG32406-PA
- Tribolium castaneum
Length = 562
Score = 43.2 bits (97), Expect = 0.023
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFM-----HMRICRGAE 619
W+ + R A +L GAF+VR S S ++LSL+ R F H I R +
Sbjct: 429 WFQAGIPREIALEILAQEPVGAFMVRESTSKPGCFALSLRVPRSFQPTGIAHYLIVRTNK 488
Query: 620 GYTLGGASTAFPSVPALMRHY-VTAQRLP 647
GY + G + F ++ +L+ H+ V + LP
Sbjct: 489 GYKIKGFTKEFTTLTSLITHHSVMPELLP 517
>UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen
resistance protein 3 (SH2 domain- containing protein 3B)
(Novel SH2-containing protein 2).; n=1; Danio rerio|Rep:
Breast cancer anti-estrogen resistance protein 3 (SH2
domain- containing protein 3B) (Novel SH2-containing
protein 2). - Danio rerio
Length = 628
Score = 43.2 bits (97), Expect = 0.023
Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 10/91 (10%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGA----EG 620
WYHG + R AE+L++ +G FL+R+S S+ +Y L+ + H +I + E
Sbjct: 46 WYHGAIPRQVAENLVQ--RDGDFLIRDSLSSPGNYVLTCQWKNSPQHFKINKRVVAMNEA 103
Query: 621 YTLGG---ASTAFPSVPALMRHYVTAQRLPV 648
Y+ F S+PAL+R+YV R PV
Sbjct: 104 YSRVQYLFEKEGFDSIPALVRYYV-GNREPV 133
>UniRef50_UPI0000503A18 Cluster: UPI0000503A18 related cluster; n=1;
Rattus norvegicus|Rep: UPI0000503A18 UniRef100 entry -
Rattus norvegicus
Length = 1066
Score = 43.2 bits (97), Expect = 0.023
Identities = 20/42 (47%), Positives = 29/42 (69%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKST 606
WY L++ +A +LL+D D GAFL+R+S S + Y L+LK T
Sbjct: 802 WYKPHLSQDQAIALLKDKDHGAFLIRDSHSFQGAYGLALKVT 843
>UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5;
Euteleostomi|Rep: C-Src protein-tyrosine kinase -
Platichthys flesus (European flounder)
Length = 120
Score = 43.2 bits (97), Expect = 0.023
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
W+HG + R +AE LL + G FLVR S + DY+L + H RI T+
Sbjct: 18 WFHGKITRNQAEQLLCPPETGLFLVRESTNFPGDYTLCVSCDGKVEHYRIIYHNGKLTI- 76
Query: 625 GASTAFPSVPALMRHY 640
F ++ L+ HY
Sbjct: 77 DEEEYFENLMQLVEHY 92
>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 743
Score = 43.2 bits (97), Expect = 0.023
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 5/106 (4%)
Query: 561 DRQGWYHGTLARVEAESLLRDAD----EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR 616
D + WYHG + R A L+ EG FLVR S Y L+L + +I
Sbjct: 6 DAERWYHGKITRENAAHLVSQGPITRREGLFLVRESTRTPGSYVLTLWAKGNVQQFQIMG 65
Query: 617 GAEGYTLGGASTAFPSVPALMRHY-VTAQRLPVRGAEHMALSTPLP 661
EG+ F + L+ HY + LPV+ +++ + P P
Sbjct: 66 HGEGWFSVDNGPLFQGLDELIHHYQLKPDGLPVQLNDYVIGNPPPP 111
>UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep:
Tyrosine kinase - Schistosoma mansoni (Blood fluke)
Length = 1264
Score = 43.2 bits (97), Expect = 0.023
Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 4/80 (5%)
Query: 563 QGWYHGTLARVEAESLLRDA--DEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
Q WYH T+ R EAES L +GAFLVR + + Y LSL S H RI
Sbjct: 200 QPWYHHTIRRYEAESRLASEGNQDGAFLVRYRKEDR-TYVLSLTSQNEPKHYRIEEYLSR 258
Query: 621 YTLGGASTAFPSVPALMRHY 640
+++ G F ++ L+ HY
Sbjct: 259 WSIEGGQ-YFETIMELIDHY 277
>UniRef50_Q63HR2 Cluster: Tensin-like C1 domain-containing
phosphatase; n=29; Eutheria|Rep: Tensin-like C1
domain-containing phosphatase - Homo sapiens (Human)
Length = 1409
Score = 43.2 bits (97), Expect = 0.023
Identities = 20/40 (50%), Positives = 28/40 (70%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
WY L+R +A +LL+D D GAFL+R+S S + Y L+LK
Sbjct: 1140 WYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALK 1179
>UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Rep:
SRC-like-adapter - Homo sapiens (Human)
Length = 276
Score = 43.2 bits (97), Expect = 0.023
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 564 GWYHGTLARVEAESLLR--DADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGY 621
GW L R +AE LL+ D G+F++R SE+ K YSLS++ R H RI R +
Sbjct: 83 GWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRH-RQVKHYRIFRLPNNW 141
Query: 622 TLGGASTAFPSVPALMRHY 640
F + L+ HY
Sbjct: 142 YYISPRLTFQCLEDLVNHY 160
>UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing
protein; n=72; Eumetazoa|Rep: Hematopoietic SH2
domain-containing protein - Homo sapiens (Human)
Length = 352
Score = 43.2 bits (97), Expect = 0.023
Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 2/74 (2%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG-YTL 623
W+HG ++R +AE+LL G+FL+R S S Y+LS K+ H + +G + +
Sbjct: 34 WFHGAISREDAENLLESQPLGSFLIRVSHS-HVGYTLSYKAQSSCCHFMVKLLDDGTFMI 92
Query: 624 GGASTAFPSVPALM 637
G A S+ AL+
Sbjct: 93 PGEKVAHTSLDALV 106
>UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21;
Bilateria|Rep: GRB2-related adapter protein - Homo
sapiens (Human)
Length = 217
Score = 43.2 bits (97), Expect = 0.023
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 565 WYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
WY G ++R AE +L + GAFL+R SES+ ++S+S+ H ++ R A G
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASG 116
>UniRef50_UPI00015B6424 Cluster: PREDICTED: similar to CG8146-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG8146-PA - Nasonia vitripennis
Length = 944
Score = 42.7 bits (96), Expect = 0.030
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 564 GWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
GWY G ++ AE +L + +G+F+VR+S + +SLS + H+RI ++
Sbjct: 758 GWYWGPISGEAAEKILSNEPDGSFIVRDSSDDHYIFSLSFRLNSCVRHVRIEHDQGNFSF 817
Query: 624 GGASTAFPS 632
G+ T F S
Sbjct: 818 -GSCTKFKS 825
>UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-related
kinase, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to Fyn-related kinase, partial -
Ornithorhynchus anatinus
Length = 186
Score = 42.7 bits (96), Expect = 0.030
Identities = 23/45 (51%), Positives = 29/45 (64%), Gaps = 2/45 (4%)
Query: 560 LDRQGWYHGTLARVEAES-LLRDADE-GAFLVRNSESAKHDYSLS 602
L + W+ G + RV+AE LL + GAFL+R SES K DYSLS
Sbjct: 142 LQAEQWFFGAIKRVDAEKQLLYSGNRPGAFLIRESESQKGDYSLS 186
>UniRef50_UPI0000DB7BD4 Cluster: PREDICTED: similar to Suppressor of
Cytokine Signaling at 16D CG8146-PA, partial; n=1; Apis
mellifera|Rep: PREDICTED: similar to Suppressor of
Cytokine Signaling at 16D CG8146-PA, partial - Apis
mellifera
Length = 804
Score = 42.7 bits (96), Expect = 0.030
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 564 GWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
GWY G ++ AE +L + +G+F+VR+S + +SLS + H+RI ++
Sbjct: 619 GWYWGPISGEAAEKILSNEPDGSFIVRDSSDDHYIFSLSFRLNSCVRHVRIEHDQGNFSF 678
Query: 624 GGASTAFPS 632
G+ T F S
Sbjct: 679 -GSCTKFKS 686
>UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,
isoform B; n=3; Endopterygota|Rep: PREDICTED: similar to
CG8874-PB, isoform B - Tribolium castaneum
Length = 801
Score = 42.7 bits (96), Expect = 0.030
Identities = 36/100 (36%), Positives = 49/100 (49%), Gaps = 10/100 (10%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKST--RGFMHMRICRGAEG-Y 621
W+HG L R E LL +G FLVR E+ ++D ++ S G H + AEG Y
Sbjct: 436 WFHGVLPREEVVRLL--TQDGDFLVR--ETTRNDECQTVLSVCWGGHKHFIVQTTAEGHY 491
Query: 622 TLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPLP 661
G AFPS+ L+ + T+ LPV G L P+P
Sbjct: 492 RFEG--PAFPSIRDLILYQYTS-GLPVTGRSGALLYKPIP 528
>UniRef50_UPI00006A0ADF Cluster: Tensin-1.; n=5; Xenopus
tropicalis|Rep: Tensin-1. - Xenopus tropicalis
Length = 1417
Score = 42.7 bits (96), Expect = 0.030
Identities = 18/40 (45%), Positives = 28/40 (70%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
WY ++R +A SLL+D D GAF++R+S S + Y L++K
Sbjct: 1146 WYKPDISRDQAISLLKDKDPGAFIIRDSHSFRGAYGLAMK 1185
>UniRef50_UPI000069FBD8 Cluster: tensin like C1 domain containing
phosphatase isoform 1; n=1; Xenopus tropicalis|Rep:
tensin like C1 domain containing phosphatase isoform 1 -
Xenopus tropicalis
Length = 1393
Score = 42.7 bits (96), Expect = 0.030
Identities = 18/40 (45%), Positives = 29/40 (72%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
WY T++R +A ++LR A+ G+FL+R+S S + Y L+LK
Sbjct: 1123 WYKPTISREQAIAILRGAEPGSFLIRDSNSFRGAYGLALK 1162
>UniRef50_UPI000069FBD7 Cluster: tensin like C1 domain containing
phosphatase isoform 1; n=1; Xenopus tropicalis|Rep:
tensin like C1 domain containing phosphatase isoform 1 -
Xenopus tropicalis
Length = 1410
Score = 42.7 bits (96), Expect = 0.030
Identities = 18/40 (45%), Positives = 29/40 (72%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
WY T++R +A ++LR A+ G+FL+R+S S + Y L+LK
Sbjct: 1138 WYKPTISREQAIAILRGAEPGSFLIRDSNSFRGAYGLALK 1177
>UniRef50_UPI000069FBD6 Cluster: tensin like C1 domain containing
phosphatase isoform 1; n=2; Xenopus tropicalis|Rep:
tensin like C1 domain containing phosphatase isoform 1 -
Xenopus tropicalis
Length = 1664
Score = 42.7 bits (96), Expect = 0.030
Identities = 18/40 (45%), Positives = 29/40 (72%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
WY T++R +A ++LR A+ G+FL+R+S S + Y L+LK
Sbjct: 1393 WYKPTISREQAIAILRGAEPGSFLIRDSNSFRGAYGLALK 1432
>UniRef50_UPI000069EEDB Cluster: UPI000069EEDB related cluster; n=1;
Xenopus tropicalis|Rep: UPI000069EEDB UniRef100 entry -
Xenopus tropicalis
Length = 163
Score = 42.7 bits (96), Expect = 0.030
Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
Query: 551 RDLVD-ATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGF 609
R LV+ + + L G+Y G L EA ++L G FLVR+S H +S+S+K G
Sbjct: 18 RQLVERSVVTLQASGFYWGPLPTKEAHAMLEREQIGTFLVRDSSQGNHLFSVSIKMESGP 77
Query: 610 MHMRI 614
+ +R+
Sbjct: 78 VSVRV 82
>UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C
(Novel SH2-containing protein 3).; n=1; Takifugu
rubripes|Rep: SH2 domain-containing protein 3C (Novel
SH2-containing protein 3). - Takifugu rubripes
Length = 580
Score = 42.7 bits (96), Expect = 0.030
Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 12/112 (10%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR--- 616
L WYHG + AESL+ + G FL+R+S S D+ L+ + +H I R
Sbjct: 31 LKSHAWYHGPVPWEVAESLV--VNHGEFLIRDSRSNHGDFVLTCHWQQKTLHFLIRRTVL 88
Query: 617 -GAEGYTLGGAS---TAFPSVPALMRHYVTAQRLPVR--GAE-HMALSTPLP 661
+E YT S AF S+PAL+ YV ++ + GA+ H ++ LP
Sbjct: 89 QSSETYTRVQYSLEEEAFDSLPALVHFYVGSKAALTQWSGAQIHRPINRTLP 140
>UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate
lymphocyte adaptor protein; n=2; Danio rerio|Rep: Novel
protein similar to vertebrate lymphocyte adaptor protein
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 279
Score = 42.7 bits (96), Expect = 0.030
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 560 LDRQGWYHGTLARVEAESLLRDAD---EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR 616
L W+HG ++RV A L++ A G FLVR SE+ + DY L+ H+R+
Sbjct: 114 LSSYSWFHGPISRVRAAYLVQHAGVSGHGNFLVRQSETRRGDYVLTFNYQGRAKHLRLSL 173
Query: 617 GAEGYTLGGASTAFPSVPALMRHY 640
E FPSV ++ H+
Sbjct: 174 -TEWGQCRVQHLRFPSVMDMLSHF 196
>UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 9 SCAF8684, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 966
Score = 42.7 bits (96), Expect = 0.030
Identities = 25/77 (32%), Positives = 45/77 (58%), Gaps = 4/77 (5%)
Query: 565 WYHGTLARVEAES-LLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
WYH L+R +AE+ L+R +GAFLVR + + +++S ++ H R+ + EG T+
Sbjct: 747 WYHANLSRSQAENMLMRVPRDGAFLVR-KRAEPNSFAISFRAEGKIKHCRVQQ--EGQTV 803
Query: 624 GGASTAFPSVPALMRHY 640
++ F S+ L+ +Y
Sbjct: 804 VLGTSEFDSLVDLISYY 820
Score = 37.5 bits (83), Expect = 1.1
Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 20/113 (17%)
Query: 565 WYHGTLA-----RVEAESLLRD------ADEGAFLVRNSESAKHDYSLSLKSTRGFMHMR 613
W+HG L R AE LL + A +G+FLVR SE+ DY+LS + H R
Sbjct: 629 WFHGKLGAGRDGRQIAERLLSEYCMETGAPDGSFLVRESETFVGDYTLSFWRSGRVQHCR 688
Query: 614 IC----RGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAE-HMALSTPLP 661
I G+ + L + F ++ AL+ HY Q++ +R E M L+ P+P
Sbjct: 689 IHSRQEAGSPKFYLTD-NLVFDTLFALINHY---QQVALRCNEFEMKLTEPVP 737
>UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p -
Drosophila melanogaster (Fruit fly)
Length = 342
Score = 42.7 bits (96), Expect = 0.030
Identities = 20/67 (29%), Positives = 38/67 (56%)
Query: 548 APPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTR 607
+P + + A + Q WY G ++R +++ L D G+FLVR+SE++ ++LS +
Sbjct: 172 SPNQIMYKACSEMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVN 231
Query: 608 GFMHMRI 614
+H R+
Sbjct: 232 VTLHYRL 238
>UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa
group|Rep: Src family kinase - Asterina miniata (Bat
star) (Patiria miniata)
Length = 563
Score = 42.7 bits (96), Expect = 0.030
Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 9/101 (8%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDA--DEGAFLVRNSESAKHDYSLSL---K 604
PR+ ++ L + W+ + R EAE L+ A G FL+R SE++ YSLS+
Sbjct: 168 PRNYIEPADVLQAEDWFFEKMTRKEAEKQLQLAGNSRGTFLIRGSETSPGAYSLSVLDHD 227
Query: 605 STRGF--MHMRI-CRGAEGYTLGGASTAFPSVPALMRHYVT 642
RGF H RI +GY + T F ++ L+ HY +
Sbjct: 228 DARGFNVKHYRIRTLDNDGYYISTRIT-FHTLHDLVNHYTS 267
>UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulatory
subunit; n=1; Aedes aegypti|Rep: Phosphatidylinositol
3-kinase regulatory subunit - Aedes aegypti (Yellowfever
mosquito)
Length = 568
Score = 42.7 bits (96), Expect = 0.030
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Query: 555 DATLPLDRQG--WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
DA P D + WY G + R E + + D +G+FLVR++ S +Y+L+LK
Sbjct: 174 DADTPADLRAAEWYWGNINRDEVKEKMTDVPDGSFLVRDASSGNGEYTLTLK 225
Score = 37.5 bits (83), Expect = 1.1
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 2/82 (2%)
Query: 561 DRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
D W T R +AE L G F++R Y+LS+K H I + G
Sbjct: 462 DESTWLVPTFNRTDAEKELASKPNGTFVIRPGSGG--PYALSIKCNDTVNHCIIQQTDRG 519
Query: 621 YTLGGASTAFPSVPALMRHYVT 642
Y + S+ +L+ HY T
Sbjct: 520 YGFAEPYNIYDSLKSLVLHYAT 541
>UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 681
Score = 42.7 bits (96), Expect = 0.030
Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query: 579 LRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLGGASTAFPSVPALMR 638
+RD G+F++R S+ + DYSLSL+ G I R + YT+GG F S+ +++
Sbjct: 1 MRDGAVGSFMIRPSDKSPGDYSLSLRYQDGVTRFLIRRQGQQYTMGG--RVFCSIDDVVK 58
Query: 639 HY 640
Y
Sbjct: 59 RY 60
>UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:
ENSANGP00000031260 - Anopheles gambiae str. PEST
Length = 491
Score = 42.7 bits (96), Expect = 0.030
Identities = 20/64 (31%), Positives = 34/64 (53%)
Query: 564 GWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
GWY G + AE +L + +G+FLVR+S + +SL+ K H+RI + ++
Sbjct: 318 GWYWGPITSEGAEKILSNEPDGSFLVRDSSDDHYIFSLTFKLNGTVRHVRIDQYQGSFSF 377
Query: 624 GGAS 627
G +
Sbjct: 378 GSCA 381
>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase
Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein
kinase Yes - Homo sapiens (Human)
Length = 543
Score = 42.7 bits (96), Expect = 0.030
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLLRDA--DEGAFLVRNSESAKHDYSLSLK--- 604
P + V + + WY G + R +AE LL + G FLVR SE+ K YSLS++
Sbjct: 143 PSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWD 202
Query: 605 STRG--FMHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
RG H +I + G F ++ L++HY
Sbjct: 203 EIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHY 240
>UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4;
Murinae|Rep: SH2 domain-containing protein 4A - Mus
musculus (Mouse)
Length = 421
Score = 42.7 bits (96), Expect = 0.030
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
W+HG L +A LL G+FL+R SE K Y+LS S G H I A Y+
Sbjct: 315 WFHGILTLKKANELLSTGVPGSFLIRVSEKIK-GYALSYLSEEGCKHFLIDASANSYSFL 373
Query: 625 G 625
G
Sbjct: 374 G 374
>UniRef50_UPI0000DB734C Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2
protein 2) (CIS-2) (STAT-induced STAT inhibitor 2)
(SSI-2); n=1; Apis mellifera|Rep: PREDICTED: similar to
Suppressor of cytokine signaling 2 (SOCS-2)
(Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced
STAT inhibitor 2) (SSI-2) - Apis mellifera
Length = 602
Score = 42.3 bits (95), Expect = 0.040
Identities = 17/51 (33%), Positives = 37/51 (72%)
Query: 564 GWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI 614
GWYH L+ ++E+LL++A G +L+R+S +++ +++S+++ RG +R+
Sbjct: 448 GWYHEGLSWQQSENLLKNAMIGRWLMRDSSDSRYMFAVSVQTARGPTSVRV 498
>UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).;
n=1; Bos taurus|Rep: SH2B adapter protein 3
(Lymphocyte-specific adapter protein Lnk) (Signal
transduction protein Lnk) (Lymphocyte adapter protein).
- Bos Taurus
Length = 526
Score = 42.3 bits (95), Expect = 0.040
Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 565 WYHGTLARVEAESL--LRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGY 621
W+HG ++RV+A L L+ D G FLVR SE+ + +Y L+ H+R+ G
Sbjct: 428 WFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTERG- 486
Query: 622 TLGGASTAFPSVPALMRHYVTAQRLPV 648
FPSV ++ H+ QR P+
Sbjct: 487 QCRVQHLHFPSVVDMLHHF---QRSPI 510
>UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 642
Score = 42.3 bits (95), Expect = 0.040
Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 10/106 (9%)
Query: 560 LDRQGWYHGTLARVEAESLLRDA--DEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR- 616
L + W+HG ++ EA L++ ++G FLVR S S Y L+ + H ++ +
Sbjct: 529 LAEEFWFHGRISHDEALVLMKREGFEDGLFLVRESCSVSDVYVLTFCMNKKVFHCQLVQD 588
Query: 617 ---GAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTP 659
G++ Y AFPS+ L+R+Y QR V G +AL P
Sbjct: 589 IGPGSKMYYRLDKGPAFPSILELIRYY---QRKTVNGIS-VALGRP 630
>UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 473
Score = 42.3 bits (95), Expect = 0.040
Identities = 22/38 (57%), Positives = 25/38 (65%), Gaps = 2/38 (5%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLS 602
WYHG ++R EAE LL DEG FLVR S+S Y LS
Sbjct: 379 WYHGPISRGEAELLLE--DEGDFLVRESKSQPGQYVLS 414
>UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33;
Mammalia|Rep: SH2B adaptor protein 1 - Homo sapiens
(Human)
Length = 756
Score = 42.3 bits (95), Expect = 0.040
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 559 PLDRQGWYHGTLARVEAESLLRDA---DEGAFLVRNSESAKHDYSLSLKSTRGFMHMRIC 615
PL W+HG L+R++A L+ G FLVR SE+ + +Y L+ H+R+
Sbjct: 521 PLSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLS 580
Query: 616 RGAEG 620
EG
Sbjct: 581 LNEEG 585
>UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;
Amniota|Rep: SH2 domain-containing protein 3C - Homo
sapiens (Human)
Length = 860
Score = 42.3 bits (95), Expect = 0.040
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 9/93 (9%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI----C 615
L WYHG + R +E+L++ G FL+R+S ++ DY L+ + +H +I
Sbjct: 215 LRSHAWYHGRIPREVSETLVQ--RNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVV 272
Query: 616 RGAEGYT---LGGASTAFPSVPALMRHYVTAQR 645
+ E YT +F VPAL+R++V +++
Sbjct: 273 KAGESYTHIQYLFEQESFDHVPALVRYHVGSRK 305
>UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15;
Tetrapoda|Rep: SH2B adapter protein 3 - Homo sapiens
(Human)
Length = 575
Score = 42.3 bits (95), Expect = 0.040
Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 565 WYHGTLARVEAESL--LRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGY 621
W+HG ++RV+A L L+ D G FLVR SE+ + +Y L+ H+R+ G
Sbjct: 364 WFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTERG- 422
Query: 622 TLGGASTAFPSVPALMRHYVTAQRLPV 648
FPSV ++ H+ QR P+
Sbjct: 423 QCRVQHLHFPSVVDMLHHF---QRSPI 446
>UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hydra
vulgaris|Rep: Tyrosine-protein kinase HTK16 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 757
Score = 42.3 bits (95), Expect = 0.040
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 5/89 (5%)
Query: 565 WYHGTLAR-VEAESLLRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRI-CRGAEGY 621
WYHG + R V + LLR +G FL+R+ +A DY LS+ +H +I C G +
Sbjct: 10 WYHGKITREVAVQVLLRKGGRDGFFLIRDCGNAPEDYVLSMMFRSQILHFQINCLGDNKF 69
Query: 622 TLGGASTAFPSVPALMRHY-VTAQRLPVR 649
++ F + L+ +Y V + LP +
Sbjct: 70 SIDN-GPIFQGLDMLISYYKVISDGLPCK 97
Score = 35.9 bits (79), Expect = 3.5
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 11/106 (10%)
Query: 565 WYHGTLARVEAESLLRDAD--EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYT 622
W H L R A +L++A +G+FL+R+S Y L+L + H +I A+ +
Sbjct: 287 WLHQNLDRNGALIILQNASMADGSFLIRSSIKCHGYYVLTLVYEKKTYHFQIKSRADRWF 346
Query: 623 LGGASTAFPSVPALMRHYV-------TAQRLPVRGAEHMALSTPLP 661
F ++P L+ HY+ T + PV AE+ PLP
Sbjct: 347 YIDDGPLFETLPHLVDHYMQYADGLPTLLQFPVPSAENR--KRPLP 390
>UniRef50_UPI0000D5672D Cluster: PREDICTED: similar to CG3208-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG3208-PA, isoform A - Tribolium castaneum
Length = 452
Score = 41.9 bits (94), Expect = 0.053
Identities = 25/70 (35%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Query: 546 PIAPPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDY-SLSLK 604
PI D V LP YHG + ++A++LL + GA+LVR+S SA + +LSLK
Sbjct: 27 PIPIISDEVPPDLPSFLGRDYHGAITHIQAQNLLSPHENGAYLVRSSRSANGQFHTLSLK 86
Query: 605 STRGFMHMRI 614
H ++
Sbjct: 87 FNDKIHHYKL 96
>UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2 -
Tribolium castaneum
Length = 473
Score = 41.9 bits (94), Expect = 0.053
Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLL--RDADEGAFLVRNSESAKHDYSLSLK 604
P + V A L ++ + W+ ++R EAE LL + G FLVR SE + YSLS+K
Sbjct: 120 PGNFVAAELSVESEDWFFENVSRKEAEKLLLAEENPRGTFLVRPSEHNPNGYSLSVK 176
>UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to
Phosphatidylinositol 3-kinase regulatory subunit alpha
(PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
p85-alpha) (PI3K); n=2; Apocrita|Rep: PREDICTED: similar
to Phosphatidylinositol 3-kinase regulatory subunit
alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
p85-alpha) (PI3K) - Apis mellifera
Length = 1256
Score = 41.9 bits (94), Expect = 0.053
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
L WY G + R E + D+ +G FLVR++ S +Y+L+L+ ++IC+
Sbjct: 834 LQEAEWYWGDITRDEVNEKMIDSPDGTFLVRDASSKGGEYTLTLRKGGTNKLIKICQRNG 893
Query: 620 GYTLGGASTAFPSVPALMRHY 640
Y F SV L+ HY
Sbjct: 894 KYGFSEPYN-FHSVIELVDHY 913
Score = 37.5 bits (83), Expect = 1.1
Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Query: 554 VDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMR 613
+D + D + W + +R +A+ +L D +G FL+R S + + Y+LS+ H
Sbjct: 1117 IDLEVHSDEKTWLYLECSRSDADRILADRPDGTFLIRTSRTGQ--YALSIMCNGTVNHCI 1174
Query: 614 ICRGAEGYTLGGASTAFPSVPALMRHY 640
I G+ S+ L+ HY
Sbjct: 1175 IYGTERGFGFAEPYNIHKSLKHLVLHY 1201
>UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3
SCAF14679, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 283
Score = 41.9 bits (94), Expect = 0.053
Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG-YTL 623
W+ +R AE LLR G F++R +S+ ++S+S++ H ++ R + G Y L
Sbjct: 58 WFQENASRSAAEELLRHKGVGEFVIRGCQSSPGEFSISVRHESDVQHFKVMRDSRGQYFL 117
Query: 624 GGASTAFPSVPALMRHYVTA 643
S F S+ L+ Y T+
Sbjct: 118 W--SEKFTSLNKLVDFYRTS 135
>UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src
homology 2 domain containing transforming protein C3;
n=1; Danio rerio|Rep: Novel protein similar to
vertebrate src homology 2 domain containing transforming
protein C3 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 501
Score = 41.9 bits (94), Expect = 0.053
Identities = 34/107 (31%), Positives = 54/107 (50%), Gaps = 11/107 (10%)
Query: 546 PIAPPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKS 605
P+AP D L R+ WYHG ++R +AE+LL +G FLVR+S + Y L+
Sbjct: 393 PVAPTED------QLRREMWYHGRMSRRDAENLL--GRDGDFLVRDSATNPGQYVLTGMQ 444
Query: 606 TRGFMHMRICRGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAE 652
H+ + EG + F S+ L+ +++T +LP+ AE
Sbjct: 445 CGLPKHLLLV-DPEG-VVRTKDMLFESISHLINYHLT-NKLPIVAAE 488
>UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep:
Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 511
Score = 41.9 bits (94), Expect = 0.053
Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 3/83 (3%)
Query: 560 LDRQGWYHGTLARVEAES-LLRDADE-GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRG 617
++ Q W+ G + RV A S L+ D + G+FLVR SES Y LS+++ H +I +
Sbjct: 129 VESQPWFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQT 188
Query: 618 AEGYTLGGASTAFPSVPALMRHY 640
+ + + A F S+ ++ HY
Sbjct: 189 GDQFYV-DALFKFSSIVEVIEHY 210
>UniRef50_Q5C0L2 Cluster: SJCHGC05893 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC05893 protein - Schistosoma
japonicum (Blood fluke)
Length = 301
Score = 41.9 bits (94), Expect = 0.053
Identities = 16/36 (44%), Positives = 28/36 (77%)
Query: 566 YHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSL 601
YHG ++R E E LL +A +G++L+R+S+ A++ Y+L
Sbjct: 45 YHGPISRQETEELLSNAQDGSYLIRDSQRAENAYTL 80
>UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7;
Tetrapoda|Rep: SH2B adapter protein 2 - Homo sapiens
(Human)
Length = 632
Score = 41.9 bits (94), Expect = 0.053
Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Query: 558 LPLDRQGWYHGTLARVEAESLL---RDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI 614
L L W+HGTL+RV+A L+ + G F++R SE+ +Y L+ H+R+
Sbjct: 410 LELSDYPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRL 469
Query: 615 CRGAEGYTLGGASTAFPSVPALMRHYVT 642
G F SV ++RH+ T
Sbjct: 470 SLNGHG-QCHVQHLWFQSVLDMLRHFHT 496
>UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep:
Zgc:109892 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 214
Score = 41.5 bits (93), Expect = 0.070
Identities = 19/56 (33%), Positives = 32/56 (57%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
W+ G ++R AE+ LR + GAFL+R SES ++S+S+ H ++ + G
Sbjct: 60 WFVGGISRQAAENRLRPLECGAFLIRESESTPGEFSVSVSYGDHVQHFKVLKDGLG 115
>UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000010943 - Anopheles gambiae
str. PEST
Length = 256
Score = 41.5 bits (93), Expect = 0.070
Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 561 DRQGWYHGTLARVEA-ESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM---RICR 616
DR WY G ++R +A + LL + + G FLVR+S + D+ L ++ H ++
Sbjct: 8 DRSSWYFGAMSRQDATDLLLNERESGVFLVRDSTTIVGDFVLCVREDSKVSHYIINKLPS 67
Query: 617 GAEGYTLGGASTAFPSVPALMRHY 640
G E + F +P L+ Y
Sbjct: 68 GDECFVYRIGDQTFADLPDLLSFY 91
>UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p -
Drosophila melanogaster (Fruit fly)
Length = 421
Score = 41.5 bits (93), Expect = 0.070
Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 565 WYHGTLAR-VEAESLLRDADEGAFLVRNSESAKHDYSLSLK---STRGFMHMRICRGAEG 620
W+ + R + E+L R + GAFLVR S + ++LSL+ + H I R G
Sbjct: 286 WFQAGIPREISLEALSRQSP-GAFLVRQSSTKPGCFALSLRVPPPSPRVAHYLILRTQRG 344
Query: 621 YTLGGASTAFPSVPALMRHY-VTAQRLPV 648
Y + G + F S+ AL+ H+ V + LPV
Sbjct: 345 YKIKGFTKEFSSLKALITHHSVMPELLPV 373
>UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra
vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 624
Score = 41.5 bits (93), Expect = 0.070
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 3/82 (3%)
Query: 565 WYHGTLARVEAESLLR---DADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGY 621
W+HG + R AE+ L+ D+G +L+R S S Y LS+ + +H I R G
Sbjct: 9 WFHGRITRDIAENCLQTTTSMDDGTYLLRESASEIGSYVLSVCKDKKVIHYAIQRQPSGM 68
Query: 622 TLGGASTAFPSVPALMRHYVTA 643
FP L+ H+ T+
Sbjct: 69 VGIADGPQFPGPVELVNHHKTS 90
Score = 41.1 bits (92), Expect = 0.092
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 562 RQGWYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG 620
+Q W+HG + R EAE L+ E G FL+R S + Y + L G H +G
Sbjct: 158 QQPWFHGVIPRTEAERRLKSLSETGMFLIRERGSPRGSYVIGLFYQGGVYHYLFESNNQG 217
Query: 621 YTLGGASTAFPSVPALMRHY 640
+ +F ++ A++ Y
Sbjct: 218 QLSIKSGRSFDNLMAVVNFY 237
>UniRef50_A7RUJ8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 186
Score = 41.5 bits (93), Expect = 0.070
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 6/99 (6%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
L + G+Y + + +A+ +LR D GAF++R+S S ++LS+++ G ++RI
Sbjct: 25 LRQSGFYWRGITKEQADIILRSCDMGAFIIRDSSSPNFLFTLSVRTVFGVTNIRIAMDRG 84
Query: 620 GYTL------GGASTAFPSVPALMRHYVTAQRLPVRGAE 652
++L +F V L+ +YV R R E
Sbjct: 85 RFSLESIDNENSEGPSFKCVVHLIYYYVKNSRHSERHLE 123
>UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7;
Endopterygota|Rep: Adapter molecule Crk - Drosophila
melanogaster (Fruit fly)
Length = 271
Score = 41.5 bits (93), Expect = 0.070
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 561 DRQGWYHGTLARVEA-ESLLRDADEGAFLVRNSESAKHDYSLSLK 604
DR WY G ++R +A E L+ + + G FLVR+S S DY L ++
Sbjct: 8 DRNSWYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVR 52
>UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C
protein; n=1; Gallus gallus|Rep: PREDICTED: similar to
SH2D3C protein - Gallus gallus
Length = 603
Score = 41.1 bits (92), Expect = 0.092
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 9/89 (10%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI----C 615
L WYHG + R +ESL++ G F++R+S ++ DY L+ + +H +I
Sbjct: 58 LRSHAWYHGRIPREVSESLVQ--RNGDFIIRDSLTSVGDYVLTCRWRNEPLHFKINKVTV 115
Query: 616 RGAEGYTLGG---ASTAFPSVPALMRHYV 641
+ ++G T +F +VPAL+R YV
Sbjct: 116 KSSDGRTRVQYLFEQESFDNVPALVRFYV 144
>UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to
phosphoinositide-3-kinase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to
phosphoinositide-3-kinase - Strongylocentrotus
purpuratus
Length = 820
Score = 41.1 bits (92), Expect = 0.092
Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 7/66 (10%)
Query: 539 GLHLNLGPIAPPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHD 598
G +++ G P+ L DA WY G+++R E L+D +G FLVR+S+ +
Sbjct: 483 GDYISTGSTDYPKSLNDAE-------WYWGSISREEVNEKLKDMPDGTFLVRDSKQEPGN 535
Query: 599 YSLSLK 604
Y+L+L+
Sbjct: 536 YTLTLR 541
>UniRef50_UPI0000D9E331 Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 7 (SOCS-7) (Nck, Ash and
phospholipase C gamma-binding protein) (Nck-associated
protein 4) (NAP-4), partial; n=1; Macaca mulatta|Rep:
PREDICTED: similar to Suppressor of cytokine signaling 7
(SOCS-7) (Nck, Ash and phospholipase C gamma-binding
protein) (Nck-associated protein 4) (NAP-4), partial -
Macaca mulatta
Length = 360
Score = 41.1 bits (92), Expect = 0.092
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 541 HLNLGPIAPPRDLVDATL-PLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDY 599
HL P A+L L++ GWY G + +AE L+ +G+FLVR+S ++
Sbjct: 179 HLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYIL 238
Query: 600 SLSLKSTRGFMH 611
SLS +S +G H
Sbjct: 239 SLSFRS-QGITH 249
>UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase,
non-receptor type 11 (Noonan syndrome 1); n=1; Danio
rerio|Rep: protein tyrosine phosphatase, non-receptor
type 11 (Noonan syndrome 1) - Danio rerio
Length = 564
Score = 41.1 bits (92), Expect = 0.092
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Query: 565 WYHGTLARVEAESLLRDAD-EGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTL 623
W+H + VEAE+LL +G+FL R S+S D++LS++ H++I + Y L
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65
>UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:
CG9098-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 944
Score = 41.1 bits (92), Expect = 0.092
Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 10/107 (9%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGA- 618
L WYHG L R AE +++ EG FLVR+ S +Y LS +S +H + +
Sbjct: 235 LRSHAWYHGALPRQRAEEIVQ--REGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNKLVL 292
Query: 619 ------EGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTP 659
E AF +VP L+ YV + + P+ A + P
Sbjct: 293 QPETVYERVQYQFEEDAFDTVPDLITFYVGSGK-PISSASGALIQFP 338
>UniRef50_O14512 Cluster: Suppressor of cytokine signaling 7; n=15;
Euteleostomi|Rep: Suppressor of cytokine signaling 7 -
Homo sapiens (Human)
Length = 581
Score = 41.1 bits (92), Expect = 0.092
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 541 HLNLGPIAPPRDLVDATL-PLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDY 599
HL P A+L L++ GWY G + +AE L+ +G+FLVR+S ++
Sbjct: 375 HLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYIL 434
Query: 600 SLSLKSTRGFMH 611
SLS +S +G H
Sbjct: 435 SLSFRS-QGITH 445
>UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34;
Euteleostomi|Rep: SHC-transforming protein 3 - Homo
sapiens (Human)
Length = 594
Score = 41.1 bits (92), Expect = 0.092
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 4/117 (3%)
Query: 544 LGPIAPPRDLVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSL 603
+ P++P L + WY G ++R EAE LL +G FLVR S + + L+
Sbjct: 478 ISPVSPRAPDAKMLEELQAETWYQGEMSRKEAEGLLE--KDGDFLVRKSTTNPGSFVLTG 535
Query: 604 KSTRGFMHMRICRGAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTPL 660
H+ + EG T+ F S+ L+ H++ + V + L P+
Sbjct: 536 MHNGQAKHLLLV-DPEG-TIRTKDRVFDSISHLINHHLESSLPIVSAGSELCLQQPV 590
>UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX;
n=36; Euteleostomi|Rep: Cytoplasmic tyrosine-protein
kinase BMX - Homo sapiens (Human)
Length = 675
Score = 41.1 bits (92), Expect = 0.092
Identities = 32/88 (36%), Positives = 46/88 (52%), Gaps = 9/88 (10%)
Query: 560 LDRQGWYHGTLARVEAESLLRD-ADEGAFLVRNSESAKHDYSLSLKS-----TRGFM-HM 612
LD W+ G ++R ++E LLR EGAF+VRNS S Y++SL S +G + H
Sbjct: 291 LDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQVGMYTVSLFSKAVNDKKGTVKHY 349
Query: 613 RICRGAEGYTLGGASTAFPSVPALMRHY 640
+ AE + F S+P L+ HY
Sbjct: 350 HVHTNAENKLYLAENYCFDSIPKLI-HY 376
>UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarcoma
virus CT10 oncogene homolog (avian)-like; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
V-crk sarcoma virus CT10 oncogene homolog (avian)-like -
Strongylocentrotus purpuratus
Length = 305
Score = 40.7 bits (91), Expect = 0.12
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
W+ G + R E ++LL G FLVR+S + D L + H I R A+ + +G
Sbjct: 18 WHFGGITRSETDNLLIQKRPGTFLVRDSRTCPGDSVLCVSENSKVSHYIITRKADQFVIG 77
Query: 625 GASTAFPSVPALMRHY 640
F ++P ++ Y
Sbjct: 78 --DQIFSTLPDILNFY 91
>UniRef50_Q4SR72 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 11
SCAF14528, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 236
Score = 40.7 bits (91), Expect = 0.12
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 8/84 (9%)
Query: 565 WYHGTLARVEAESLLR--DADEGAFLVRNSESAKHDYSLSLKSTRG------FMHMRICR 616
W ++R +A LL + GAFL+R SE++ YSLS+ G H RIC
Sbjct: 77 WLFAGVSRSKAVELLMLPNNRNGAFLIRESETSADCYSLSILRRSGSPCMDSVKHYRICC 136
Query: 617 GAEGYTLGGASTAFPSVPALMRHY 640
G+ FPS+ L+ HY
Sbjct: 137 LQNGWVYISPGLTFPSLHHLVEHY 160
>UniRef50_Q8WP81 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 533
Score = 40.7 bits (91), Expect = 0.12
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRG-FMHMRICRGAEGYTL 623
W+HG ++R ++E LL G+FLVR SE Y++S S G F H + + EGY
Sbjct: 395 WFHGIISRDQSEVLLTHKPTGSFLVRVSERI-WGYTVSYASRDGSFKHFLVEKIKEGYQF 453
Query: 624 GGAS 627
G +
Sbjct: 454 LGTN 457
>UniRef50_Q7Q5B6 Cluster: ENSANGP00000004338; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000004338 - Anopheles gambiae
str. PEST
Length = 1852
Score = 40.7 bits (91), Expect = 0.12
Identities = 16/40 (40%), Positives = 24/40 (60%)
Query: 341 ISDKSSQEPASETSDNNKNNNSQKVSPEEGDTGNATIQTA 380
++ SS +PA TS NN NN S P +GD G +T+ ++
Sbjct: 340 LTGSSSSQPAGGTSSNNNNNTSNNPPPSQGDAGGSTLTSS 379
>UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6;
Endopterygota|Rep: Tyrosine-protein kinase Src64B -
Drosophila melanogaster (Fruit fly)
Length = 552
Score = 40.7 bits (91), Expect = 0.12
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 550 PRDLVDATLPLDRQGWYHGTLARVEAESLL--RDADEGAFLVRNSESAKHDYSLSLK--- 604
P + V ++ + W+ + R EA+ LL + G FLVR SE + YSLS+K
Sbjct: 147 PLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWE 206
Query: 605 STRGF--MHMRICRGAEGYTLGGASTAFPSVPALMRHY 640
RG+ H RI G + FPS+ AL+ Y
Sbjct: 207 DGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAY 244
>UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 524
Score = 40.3 bits (90), Expect = 0.16
Identities = 31/81 (38%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR---GAEG- 620
W HG R EAE LL+D G FL+R SES K + LS + H I GA G
Sbjct: 128 WLHGFATRREAEQLLQDKPLGCFLLRLSES-KIGFVLSYRGEDRCRHFIIEEEESGAFGS 186
Query: 621 -YTLGGASTAFPSVPALMRHY 640
Y + G S+ S+ L+ +Y
Sbjct: 187 VYLIAGESSHHKSLENLISYY 207
>UniRef50_UPI0000F1ED8A Cluster: PREDICTED: similar to TNS1 protein,
partial; n=1; Danio rerio|Rep: PREDICTED: similar to TNS1
protein, partial - Danio rerio
Length = 1672
Score = 40.3 bits (90), Expect = 0.16
Identities = 16/40 (40%), Positives = 28/40 (70%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
WY ++R +A ++L+D D GAF++R+S S + Y L++K
Sbjct: 1402 WYKPDISRDQAINMLKDQDPGAFVIRDSHSFRGAYGLAMK 1441
>UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,
isoform A, partial; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to CG9098-PA, isoform A, partial -
Tribolium castaneum
Length = 851
Score = 40.3 bits (90), Expect = 0.16
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 10/107 (9%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICR--- 616
L WYHG + R AE ++R +EG FLVR+ S +Y L+ ++ +H I +
Sbjct: 171 LRSHAWYHGAIPRSRAEDIVR--EEGGFLVRDCTSQPGNYVLTCRTKTQPLHFVINKIIL 228
Query: 617 ----GAEGYTLGGASTAFPSVPALMRHYVTAQRLPVRGAEHMALSTP 659
E AF +VP L+ YV + + P+ A + P
Sbjct: 229 QPDTVYEHVQFQFEEDAFDTVPDLITFYVGSGK-PITAASGARIQFP 274
>UniRef50_Q4SM94 Cluster: Chromosome 3 SCAF14553, whole genome shotgun
sequence; n=2; Tetraodontidae|Rep: Chromosome 3
SCAF14553, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1679
Score = 40.3 bits (90), Expect = 0.16
Identities = 16/40 (40%), Positives = 28/40 (70%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
WY ++R +A +LL+D + GAF++R+S S + Y L++K
Sbjct: 1390 WYKPDISREQAINLLKDREPGAFIIRDSHSFRGAYGLAMK 1429
>UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein;
n=1; Suberites domuncula|Rep: Bruton's tyrosine
kinase-like protein - Suberites domuncula (Sponge)
Length = 700
Score = 40.3 bits (90), Expect = 0.16
Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Query: 560 LDRQGWYHGTLARVEAESLLR-DADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGA 618
LD + W+ L+R AE++L+ + EG F+VRNS S ++ Y+LS+ H I
Sbjct: 313 LDSEEWFFPQLSRTRAENILKGEGREGGFVVRNS-SRENMYTLSICHEGQVRHYHIKLDE 371
Query: 619 EGYTLGGASTAFPSVPALMRHY 640
FPS+ L+ ++
Sbjct: 372 SNKYFISEKHRFPSIKELIEYH 393
>UniRef50_Q4H2S6 Cluster: Suppressor of cytokine signaling; n=1;
Ciona intestinalis|Rep: Suppressor of cytokine signaling
- Ciona intestinalis (Transparent sea squirt)
Length = 696
Score = 40.3 bits (90), Expect = 0.16
Identities = 20/50 (40%), Positives = 30/50 (60%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRI 614
WY G ++ EA+ LR + G FL+R+S ++ YSLSL + G +RI
Sbjct: 502 WYWGGMSGQEAKRKLRGSSPGTFLLRDSADPRYLYSLSLMTKSGPTSIRI 551
>UniRef50_Q04205 Cluster: Tensin; n=12; Euteleostomi|Rep: Tensin -
Gallus gallus (Chicken)
Length = 1744
Score = 40.3 bits (90), Expect = 0.16
Identities = 16/40 (40%), Positives = 28/40 (70%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
WY ++R +A +LL+D + GAF++R+S S + Y L++K
Sbjct: 1472 WYKPDISREQAIALLKDREPGAFIIRDSHSFRGAYGLAMK 1511
>UniRef50_Q9HBL0 Cluster: Tensin-1; n=44; Eumetazoa|Rep: Tensin-1 -
Homo sapiens (Human)
Length = 1735
Score = 40.3 bits (90), Expect = 0.16
Identities = 16/40 (40%), Positives = 28/40 (70%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
WY ++R +A +LL+D + GAF++R+S S + Y L++K
Sbjct: 1463 WYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMK 1502
>UniRef50_O75159 Cluster: Suppressor of cytokine signaling 5; n=31;
Euteleostomi|Rep: Suppressor of cytokine signaling 5 -
Homo sapiens (Human)
Length = 536
Score = 40.3 bits (90), Expect = 0.16
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 553 LVDATLPLDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHM 612
LV L + Y G + R EAE+LL EG FL+R+S + +S+S + +H
Sbjct: 369 LVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHA 428
Query: 613 RICRGAEGYTLGGASTAF---PSVPALMRHY 640
RI + ++ +V L+ HY
Sbjct: 429 RIEQWNHNFSFDAHDPCVFHSSTVTGLLEHY 459
>UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing
protein; n=2; Murinae|Rep: Hematopoietic SH2
domain-containing protein - Mus musculus (Mouse)
Length = 334
Score = 40.3 bits (90), Expect = 0.16
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 5/86 (5%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEG-YTL 623
W+HGT++R AE++L G FL+R S S Y+LS K+ H + +G
Sbjct: 34 WFHGTISREAAENMLESQPLGTFLIRVSHS-HVGYTLSYKAQTCCRHFMVKLSEDGTCAF 92
Query: 624 GGASTAFPSVPALMRHYVTAQRLPVR 649
G S+ AL+ + Q+ P+R
Sbjct: 93 AGDHMTHASLHALVTFH---QQKPIR 115
>UniRef50_UPI00015B5375 Cluster: PREDICTED: similar to tensin; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to tensin -
Nasonia vitripennis
Length = 1147
Score = 39.9 bits (89), Expect = 0.21
Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 3/58 (5%)
Query: 550 PRDLVDATLPLDRQG---WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
P ++ DA + R WY ++R +A ++LRDA G F+VR+S S + L+LK
Sbjct: 844 PHEVADANVKFVRDTSKIWYKPNISREQAIAMLRDAAPGTFVVRDSNSFPGAFGLALK 901
>UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14770, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 789
Score = 39.9 bits (89), Expect = 0.21
Identities = 18/38 (47%), Positives = 27/38 (71%), Gaps = 1/38 (2%)
Query: 565 WYHGTLARVEAESLL-RDADEGAFLVRNSESAKHDYSL 601
WYH + R +AE LL + A +G+FL+R+SES + Y+L
Sbjct: 1 WYHSNITRSKAEDLLSKAARDGSFLIRDSESIQGAYAL 38
>UniRef50_Q8INY1 Cluster: CG15154-PB, isoform B; n=6; Coelomata|Rep:
CG15154-PB, isoform B - Drosophila melanogaster (Fruit
fly)
Length = 720
Score = 39.9 bits (89), Expect = 0.21
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 560 LDRQGWYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAE 619
+ +Y G + R EAE LL EG FL+R+S + +S++ + +H RI +
Sbjct: 469 ITNSSFYWGKMDRYEAEHLLEGKPEGTFLLRDSAQEEFLFSVTFRKYGRSLHARIEQSGH 528
Query: 620 GYTLGGASTAF---PSVPALMRHY 640
++ P+V L+ HY
Sbjct: 529 KFSFDCHDPCVFTAPTVTGLLEHY 552
>UniRef50_Q4JSB7 Cluster: Tensin; n=3; Culicidae|Rep: Tensin -
Anopheles gambiae (African malaria mosquito)
Length = 1494
Score = 39.9 bits (89), Expect = 0.21
Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
Query: 504 NASSSQSVEDLNQGNKLKSSLKLNFDXXXXXXXXKGLHLNLGPIAPPRDLVDATLPLDRQ 563
N + ++ +DL GN+ ++ +N + + + P+++ + R
Sbjct: 1155 NPAYQRTTKDLFSGNQQRTQELVNQNETLSCYTSRRNSTTSNANSEPQEVAPQFVKFARD 1214
Query: 564 G---WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLK 604
WY ++R EA +LLR+A G F+VR+S + + Y L +K
Sbjct: 1215 SSKYWYKPNISREEAIALLRNAAPGTFIVRDSTTFANAYGLVVK 1258
>UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein plc-3 - Caenorhabditis elegans
Length = 1299
Score = 39.9 bits (89), Expect = 0.21
Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 5/89 (5%)
Query: 563 QGWYHGTLARVEAESLLRDADE-GAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGY 621
Q W+ T + +AE LL E GAFL+R S + Y LSLK F H R+ R +
Sbjct: 662 QPWFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKVDGEFWHYRLKRDGRIF 721
Query: 622 TLGGASTAFPSVPALMRHYVTAQRLPVRG 650
+ F ++ ++ Y A R VRG
Sbjct: 722 VVN--QKVFENLNQIVEFY--ANREFVRG 746
>UniRef50_A7SKN8 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 155
Score = 39.9 bits (89), Expect = 0.21
Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 565 WYHGTLARVEAESLLRDADEGAFLVRNSESAKHDYSLSLKSTRGFMHMRICRGAEGYTLG 624
WY G + R EAE +L +G FL+R+S ++ +S+S + H RI + Y+
Sbjct: 16 WYWGKINRFEAERVLDGLPDGTFLLRDSAQYQYLFSVSFRRYFRTYHARIEQWKHRYSFD 75
Query: 625 GAST-AFPS--VPALMRHYVTAQR 645
S +F S + L++HY A++
Sbjct: 76 KPSDYSFCSKTLHELLQHYSQAEQ 99
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.313 0.130 0.366
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 609,740,648
Number of Sequences: 1657284
Number of extensions: 22459395
Number of successful extensions: 78656
Number of sequences better than 10.0: 375
Number of HSP's better than 10.0 without gapping: 193
Number of HSP's successfully gapped in prelim test: 182
Number of HSP's that attempted gapping in prelim test: 78080
Number of HSP's gapped (non-prelim): 574
length of query: 665
length of database: 575,637,011
effective HSP length: 106
effective length of query: 559
effective length of database: 399,964,907
effective search space: 223580383013
effective search space used: 223580383013
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.9 bits)
S2: 76 (34.7 bits)
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