Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001513-TA|BGIBMGA001513-PA|IPR000209|Peptidase S8 and
S53, subtilisin, kexin, sedolisin, IPR008979|Galactose-binding like,
IPR009020|Proteinase inhibitor, propeptide, IPR009030|Growth factor,
receptor, IPR002884|Proprotein convertase, P
(1152 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X17094-1|CAA34948.1| 794|Homo sapiens protein ( Human fur mRNA ... 603 e-171
BC012181-1|AAH12181.1| 794|Homo sapiens furin (paired basic ami... 603 e-171
AY358963-1|AAQ89322.1| 755|Homo sapiens prohormone convertase p... 581 e-165
M80482-1|AAA59998.1| 969|Homo sapiens subtilisin-like protease ... 565 e-160
D87995-1|BAA21793.1| 956|Homo sapiens PACE4A-II protein. 565 e-160
D87994-1|BAA21792.1| 962|Homo sapiens PACE4E-II protein. 565 e-160
D87993-1|BAA21791.1| 975|Homo sapiens PACE4E-I protein. 565 e-160
AB001914-4|BAA21627.1| 975|Homo sapiens PACE4E-I protein. 565 e-160
AB001914-3|BAA21626.1| 962|Homo sapiens PACE4E-II protein. 565 e-160
AB001914-2|BAA21625.1| 956|Homo sapiens PACE4A-II protein. 565 e-160
AB001914-1|BAA21624.1| 969|Homo sapiens PACE4A-I protein. 565 e-160
D28513-1|BAA05871.1| 652|Homo sapiens kexin-like protease protein. 554 e-157
AB001914-6|BAA21623.1| 623|Homo sapiens PACE4CS protein. 554 e-157
AB001914-5|BAA21621.1| 652|Homo sapiens PACE4C protein. 554 e-157
U56387-1|AAC50643.2| 913|Homo sapiens protease PC6 isoform A pr... 551 e-156
BC012064-1|AAH12064.1| 913|Homo sapiens proprotein convertase s... 551 e-156
AL359253-2|CAH73743.1| 913|Homo sapiens proprotein convertase s... 551 e-156
AL359253-1|CAH73742.1| 690|Homo sapiens proprotein convertase s... 551 e-156
AL353607-2|CAI41233.1| 913|Homo sapiens proprotein convertase s... 551 e-156
AL353607-1|CAI41232.1| 690|Homo sapiens proprotein convertase s... 551 e-156
U49114-1|AAA91807.1| 899|Homo sapiens prohormone convertase 5 p... 549 e-155
M90753-1|AAA59918.1| 753|Homo sapiens PC1 protein. 539 e-152
BC130295-1|AAI30296.1| 753|Homo sapiens proprotein convertase s... 539 e-152
X64810-1|CAA46031.1| 753|Homo sapiens PC1/PC3 protein. 537 e-152
D28514-1|BAA05872.1| 497|Homo sapiens kexin-like protease protein. 537 e-152
AB001914-8|BAA21622.1| 497|Homo sapiens PACE4D protein. 537 e-152
AB208874-1|BAD92111.1| 724|Homo sapiens proprotein convertase s... 537 e-151
D73407-1|BAA11133.1| 753|Homo sapiens prohormone convertase 3 p... 534 e-151
BC040546-1|AAH40546.1| 619|Homo sapiens PCSK2 protein protein. 481 e-135
M95971-1|AAA59919.1| 638|Homo sapiens neuroendocrine convertase... 481 e-135
BC005815-1|AAH05815.1| 638|Homo sapiens proprotein convertase s... 481 e-135
AL359511-3|CAC34957.2| 619|Homo sapiens proprotein convertase s... 481 e-135
AL359511-2|CAI20085.1| 638|Homo sapiens proprotein convertase s... 481 e-135
AL121779-2|CAB96732.2| 619|Homo sapiens proprotein convertase s... 481 e-135
AL121779-1|CAI19155.1| 638|Homo sapiens proprotein convertase s... 481 e-135
AL031675-2|CAA21069.2| 619|Homo sapiens proprotein convertase s... 481 e-135
AL031675-1|CAI22648.1| 638|Homo sapiens proprotein convertase s... 481 e-135
AL031664-3|CAB89428.2| 619|Homo sapiens proprotein convertase s... 481 e-135
AL031664-2|CAI21690.1| 638|Homo sapiens proprotein convertase s... 481 e-135
J05252-1|AAA60032.1| 638|Homo sapiens endoprotease protein. 479 e-134
AB001914-7|BAA21620.1| 487|Homo sapiens PACE4B protein. 438 e-122
U40623-1|AAC50417.1| 785|Homo sapiens PC8 precursor protein. 413 e-114
U33849-1|AAB03087.1| 785|Homo sapiens lymphoma proprotein conve... 413 e-114
BT006870-1|AAP35516.1| 785|Homo sapiens proprotein convertase s... 413 e-114
BC010696-1|AAH10696.1| 785|Homo sapiens proprotein convertase s... 413 e-114
AK222907-1|BAD96627.1| 785|Homo sapiens proprotein convertase s... 409 e-113
AM491522-1|CAM33226.1| 357|Homo sapiens proprotein convertase s... 394 e-109
AB208955-1|BAD92192.1| 800|Homo sapiens paired basic amino acid... 394 e-109
BC006357-1|AAH06357.1| 591|Homo sapiens PCSK7 protein protein. 373 e-102
X04329-1|CAA27860.1| 499|Homo sapiens furin protein. 348 8e-95
AL589653-1|CAI40809.1| 1560|Homo sapiens proprotein convertase s... 278 7e-74
AL391868-1|CAI40675.1| 1560|Homo sapiens proprotein convertase s... 278 7e-74
AL353607-3|CAI41234.1| 1560|Homo sapiens proprotein convertase s... 278 7e-74
X15723-1|CAA33745.1| 280|Homo sapiens furin protein. 231 1e-59
BC036354-1|AAH36354.1| 242|Homo sapiens PCSK4 protein protein. 75 2e-12
AF057710-1|AAD55137.1| 259|Homo sapiens lymphoma pro-protein co... 71 2e-11
BC131820-1|AAI31821.1| 1976|Homo sapiens FRAS1 protein protein. 44 0.003
BC064487-1|AAH64487.1| 651|Homo sapiens FRAS1 protein protein. 44 0.003
BC052281-1|AAH52281.1| 651|Homo sapiens FRAS1 protein protein. 44 0.003
AK027833-1|BAB55399.1| 441|Homo sapiens protein ( Homo sapiens ... 44 0.003
AJ512501-1|CAD54734.1| 4007|Homo sapiens extracellular matrix pr... 44 0.003
DQ318235-1|ABC54570.1| 263|Homo sapiens R-spondin 1 protein. 40 0.039
DQ165085-1|ABA54598.1| 200|Homo sapiens R-spondin isoform 2 pro... 40 0.039
DQ165084-1|ABA54597.1| 263|Homo sapiens R-spondin isoform 1 pro... 40 0.039
BC114966-1|AAI14967.1| 263|Homo sapiens R-spondin homolog (Xeno... 40 0.039
AL513220-4|CAI15785.1| 236|Homo sapiens R-spondin homolog (Xeno... 40 0.039
AL513220-3|CAM12883.1| 263|Homo sapiens R-spondin homolog (Xeno... 40 0.039
AL513220-2|CAM12882.1| 200|Homo sapiens R-spondin homolog (Xeno... 40 0.039
AK098225-1|BAC05263.1| 236|Homo sapiens protein ( Homo sapiens ... 40 0.039
S65442-1|AAB28140.1| 69|Homo sapiens furin protein. 39 0.090
BC036554-1|AAH36554.1| 179|Homo sapiens RSPO2 protein protein. 37 0.48
BC027938-1|AAH27938.1| 176|Homo sapiens RSPO2 protein protein. 37 0.48
AY358166-1|AAQ88533.1| 243|Homo sapiens QFRL9384 protein. 37 0.48
AL353607-4|CAI41235.1| 101|Homo sapiens proprotein convertase s... 36 0.63
BC008720-1|AAH08720.1| 422|Homo sapiens cysteine-rich with EGF-... 35 1.5
AY358363-1|AAQ88729.1| 420|Homo sapiens CRELD1 protein. 35 1.5
AF452623-1|AAM75206.1| 420|Homo sapiens cysteine-rich with EGF-... 35 1.5
AB209088-1|BAD92325.1| 514|Homo sapiens synapsin II isoform IIb... 35 1.9
BC022367-1|AAH22367.1| 272|Homo sapiens R-spondin 3 homolog (Xe... 34 2.6
AL590733-2|CAH71125.1| 292|Homo sapiens R-spondin 3 homolog (Xe... 34 2.6
AL590733-1|CAH71124.1| 272|Homo sapiens R-spondin 3 homolog (Xe... 34 2.6
AL031776-2|CAI20142.1| 292|Homo sapiens R-spondin 3 homolog (Xe... 34 2.6
AL031776-1|CAI20141.1| 272|Homo sapiens R-spondin 3 homolog (Xe... 34 2.6
AK027346-1|BAB55051.1| 292|Homo sapiens protein ( Homo sapiens ... 34 2.6
AF251057-1|AAK34947.1| 272|Homo sapiens thrombospondin protein. 34 2.6
DQ355152-1|ABC75877.1| 172|Homo sapiens R-spondin family member... 33 4.5
AL050325-3|CAM28322.1| 172|Homo sapiens R-spondin family, membe... 33 4.5
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 33 5.9
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 33 5.9
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 33 5.9
AK131568-1|BAD18701.1| 435|Homo sapiens protein ( Homo sapiens ... 33 5.9
AB231710-1|BAE46876.1| 82|Homo sapiens hypothetical protein pr... 33 5.9
X60299-1|CAA42841.1| 680|Homo sapiens KALIG-1 protein. 33 7.8
S60085-1|AAB20108.1| 679|Homo sapiens ADMLX protein. 33 7.8
M97252-1|AAA59202.1| 680|Homo sapiens KAL protein. 33 7.8
AL050325-2|CAB65783.4| 234|Homo sapiens R-spondin family, membe... 33 7.8
>X17094-1|CAA34948.1| 794|Homo sapiens protein ( Human fur mRNA for
furin. ).
Length = 794
Score = 603 bits (1489), Expect = e-171
Identities = 290/513 (56%), Positives = 353/513 (68%), Gaps = 10/513 (1%)
Query: 83 LNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGGLDMNVIPAWREGITGRGVVVTILDDG 142
L ++ R D+ DPK+P WYL+ D+NV AW +G TG G+VV+ILDDG
Sbjct: 96 LEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDG 155
Query: 143 LETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXX 202
+E +HPDL NYDP AS+DVN DPDPQPRY ++ NRHGTRCAGEVAA ANN +C
Sbjct: 156 IEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGV 215
Query: 203 XXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFI 262
MLDG+VTD VEARSL LNP H+ IYSASWGP+DDGKTVDGP LA AF
Sbjct: 216 AYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFF 275
Query: 263 EGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSS 322
GV++GR G GSIFVWASGNGG+EHD+CNCDGYTNSI+TLSISSAT+ G+VPWYSE CSS
Sbjct: 276 RGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSS 335
Query: 323 TLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQH 382
TLA TYSSG NE Q+VTTDL CT HTGTSASAPLAAGI AL L+AN++LTWRDMQH
Sbjct: 336 TLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQH 395
Query: 383 IVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAA 442
+VV+T++P L+ + +W NGVGR VSHS+GYGLLDA MV LA+ W TV PQR+C +
Sbjct: 396 LVVQTSKPAHLN-ANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDI 454
Query: 443 PRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTSPAGTN 498
+ I R + ++ V++C G + LEH QAR++LS RRGDL I L SP GT
Sbjct: 455 LTEPKDIGKR--LEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTR 512
Query: 499 VTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEWSLTLYG 558
TLLA RPHD S GFN W FM+ H W E+P GEW LE+ N +L +++L LYG
Sbjct: 513 STLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYG 572
Query: 559 TSTPAAKNDPIPFRNPIIRNKGNASRPVVLQAG 591
T A + P+P + + ++ VV + G
Sbjct: 573 T---APEGLPVPPESSGCKTLTSSQACVVCEEG 602
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/49 (53%), Positives = 33/49 (67%)
Query: 1 IFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRD 49
IF D+YHF HR +TKRSL+P H RL+ + +V+W EQQ R KRD
Sbjct: 60 IFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRD 108
Score = 42.3 bits (95), Expect = 0.010
Identities = 15/29 (51%), Positives = 19/29 (65%)
Query: 1018 ICLPCHYTCATCAGPHDSQCVSCLDDAEL 1046
+C PCH +CATC GP + C+SC A L
Sbjct: 640 VCAPCHASCATCQGPALTDCLSCPSHASL 668
>BC012181-1|AAH12181.1| 794|Homo sapiens furin (paired basic amino
acid cleaving enzyme) protein.
Length = 794
Score = 603 bits (1489), Expect = e-171
Identities = 290/513 (56%), Positives = 353/513 (68%), Gaps = 10/513 (1%)
Query: 83 LNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGGLDMNVIPAWREGITGRGVVVTILDDG 142
L ++ R D+ DPK+P WYL+ D+NV AW +G TG G+VV+ILDDG
Sbjct: 96 LEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDG 155
Query: 143 LETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXX 202
+E +HPDL NYDP AS+DVN DPDPQPRY ++ NRHGTRCAGEVAA ANN +C
Sbjct: 156 IEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGV 215
Query: 203 XXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFI 262
MLDG+VTD VEARSL LNP H+ IYSASWGP+DDGKTVDGP LA AF
Sbjct: 216 AYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFF 275
Query: 263 EGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSS 322
GV++GR G GSIFVWASGNGG+EHD+CNCDGYTNSI+TLSISSAT+ G+VPWYSE CSS
Sbjct: 276 RGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSS 335
Query: 323 TLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQH 382
TLA TYSSG NE Q+VTTDL CT HTGTSASAPLAAGI AL L+AN++LTWRDMQH
Sbjct: 336 TLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQH 395
Query: 383 IVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAA 442
+VV+T++P L+ + +W NGVGR VSHS+GYGLLDA MV LA+ W TV PQR+C +
Sbjct: 396 LVVQTSKPAHLN-ANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDI 454
Query: 443 PRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTSPAGTN 498
+ I R + ++ V++C G + LEH QAR++LS RRGDL I L SP GT
Sbjct: 455 LTEPKDIGKR--LEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTR 512
Query: 499 VTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEWSLTLYG 558
TLLA RPHD S GFN W FM+ H W E+P GEW LE+ N +L +++L LYG
Sbjct: 513 STLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYG 572
Query: 559 TSTPAAKNDPIPFRNPIIRNKGNASRPVVLQAG 591
T A + P+P + + ++ VV + G
Sbjct: 573 T---APEGLPVPPESSGCKTLTSSQACVVCEEG 602
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/49 (53%), Positives = 33/49 (67%)
Query: 1 IFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRD 49
IF D+YHF HR +TKRSL+P H RL+ + +V+W EQQ R KRD
Sbjct: 60 IFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRD 108
Score = 42.3 bits (95), Expect = 0.010
Identities = 15/29 (51%), Positives = 19/29 (65%)
Query: 1018 ICLPCHYTCATCAGPHDSQCVSCLDDAEL 1046
+C PCH +CATC GP + C+SC A L
Sbjct: 640 VCAPCHASCATCQGPALTDCLSCPSHASL 668
>AY358963-1|AAQ89322.1| 755|Homo sapiens prohormone convertase
protein.
Length = 755
Score = 581 bits (1435), Expect = e-165
Identities = 268/464 (57%), Positives = 331/464 (71%), Gaps = 9/464 (1%)
Query: 102 DPKWPHMWYLNRGGGLDMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYDPAASYD 161
DP + WY+N D++++ AW +G++G+G+VV++LDDG+E DHPDL ANYDP ASYD
Sbjct: 120 DPWFSKQWYMNSEAQPDLSILQAWSQGLSGQGIVVSVLDDGIEKDHPDLWANYDPLASYD 179
Query: 162 VNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXXMLDGDVTDV 221
N DPDPQPRY NRHGTRCAGEVAA ANN C MLDG +TDV
Sbjct: 180 FNDYDPDPQPRYTPSKENRHGTRCAGEVAAMANNGFCGVGVAFNARIGGVRMLDGTITDV 239
Query: 222 VEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSIFVWASG 281
+EA+SLSL PQH+ IYSASWGP+DDG+TVDGPG+L AF GVTKGR G G++F+WASG
Sbjct: 240 IEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGLGTLFIWASG 299
Query: 282 NGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINENQVVTT 341
NGG +DNCNCDGYTNSI TLS+ S T++G VPWYSE C+STL TYSSG + Q+VTT
Sbjct: 300 NGGLHYDNCNCDGYTNSIHTLSVGSTTQQGRVPWYSEACASTLTTTYSSGVATDPQIVTT 359
Query: 342 DLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSLSGEWRI 401
DLHH CT HTGTSASAPLAAG+ ALAL+AN LTWRDMQH+VVR ++P L + +WR
Sbjct: 360 DLHHGCTDQHTGTSASAPLAAGMIALALEANPFLTWRDMQHLVVRASKPAHLQ-AEDWRT 418
Query: 402 NGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCEL-AAPRPHRMIPPRSAIALQLA 460
NGVGR VSH +GYGLLDA +V A+TW PQR+C + RP ++P I ++
Sbjct: 419 NGVGRQVSHHYGYGLLDAGLLVDTARTWLPTQPQRKCAVRVQSRPTPILP---LIYIREN 475
Query: 461 VSSCPG----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSSHSGFNS 516
VS+C G + LEHVQA+++LS +RRGDL I+LTSP GT TL+A RP D S G+N+
Sbjct: 476 VSACAGLHNSIRSLEHVQAQLTLSYSRRGDLEISLTSPMGTRSTLVAIRPLDVSTEGYNN 535
Query: 517 WPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEWSLTLYGTS 560
W FMS H W ENP G W L + N+G Y +L ++L LYGT+
Sbjct: 536 WVFMSTHFWDENPQGVWTLGLENKGYYFNTGTLYRYTLLLYGTA 579
Score = 41.1 bits (92), Expect = 0.022
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Query: 1 IFDDHYHFH--HRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
IF D +FH HR + ++SLTP H L+ + +V+W +QQ + R KR
Sbjct: 64 IFSDGQYFHLRHRGVVQQSLTPHWGHRLHLKKNPKVQWFQQQTLQRRVKR 113
>M80482-1|AAA59998.1| 969|Homo sapiens subtilisin-like protease
protein.
Length = 969
Score = 565 bits (1395), Expect = e-160
Identities = 273/493 (55%), Positives = 333/493 (67%), Gaps = 15/493 (3%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYM----GRA 547
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+ + + +
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQG 620
Query: 548 SLQEWSLTLYGTS 560
L+EWSL LYGT+
Sbjct: 621 KLKEWSLILYGTA 633
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 945 CAKGL--HLYNGRCYSRCPDGTYANEISME----RSSRRRNLTIFSEGSLSKRQDGSLKS 998
C +G H C + CP G YA+E S ++ + + ++ K +
Sbjct: 767 CRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARG 826
Query: 999 SALEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
S + D EP + + C CH+TC TC GP +C+ C
Sbjct: 827 SCIP--DCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 866
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>D87995-1|BAA21793.1| 956|Homo sapiens PACE4A-II protein.
Length = 956
Score = 565 bits (1395), Expect = e-160
Identities = 273/493 (55%), Positives = 333/493 (67%), Gaps = 15/493 (3%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYM----GRA 547
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+ + + +
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQG 620
Query: 548 SLQEWSLTLYGTS 560
L+EWSL LYGT+
Sbjct: 621 KLKEWSLILYGTA 633
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 945 CAKGL--HLYNGRCYSRCPDGTYANEISME----RSSRRRNLTIFSEGSLSKRQDGSLKS 998
C +G H C + CP G YA+E S ++ + + ++ K +
Sbjct: 754 CRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARG 813
Query: 999 SALEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
S + D EP + + C CH+TC TC GP +C+ C
Sbjct: 814 SCIP--DCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 853
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>D87994-1|BAA21792.1| 962|Homo sapiens PACE4E-II protein.
Length = 962
Score = 565 bits (1395), Expect = e-160
Identities = 273/493 (55%), Positives = 333/493 (67%), Gaps = 15/493 (3%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYM----GRA 547
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+ + + +
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQG 620
Query: 548 SLQEWSLTLYGTS 560
L+EWSL LYGT+
Sbjct: 621 KLKEWSLILYGTA 633
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 945 CAKGL--HLYNGRCYSRCPDGTYANEISME----RSSRRRNLTIFSEGSLSKRQDGSLKS 998
C +G H C + CP G YA+E S ++ + + ++ K +
Sbjct: 754 CRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARG 813
Query: 999 SALEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
S + D EP + + C CH+TC TC GP +C+ C
Sbjct: 814 SCIP--DCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 853
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>D87993-1|BAA21791.1| 975|Homo sapiens PACE4E-I protein.
Length = 975
Score = 565 bits (1395), Expect = e-160
Identities = 273/493 (55%), Positives = 333/493 (67%), Gaps = 15/493 (3%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYM----GRA 547
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+ + + +
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQG 620
Query: 548 SLQEWSLTLYGTS 560
L+EWSL LYGT+
Sbjct: 621 KLKEWSLILYGTA 633
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 945 CAKGL--HLYNGRCYSRCPDGTYANEISME----RSSRRRNLTIFSEGSLSKRQDGSLKS 998
C +G H C + CP G YA+E S ++ + + ++ K +
Sbjct: 767 CRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARG 826
Query: 999 SALEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
S + D EP + + C CH+TC TC GP +C+ C
Sbjct: 827 SCIP--DCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 866
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>AB001914-4|BAA21627.1| 975|Homo sapiens PACE4E-I protein.
Length = 975
Score = 565 bits (1395), Expect = e-160
Identities = 273/493 (55%), Positives = 333/493 (67%), Gaps = 15/493 (3%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYM----GRA 547
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+ + + +
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQG 620
Query: 548 SLQEWSLTLYGTS 560
L+EWSL LYGT+
Sbjct: 621 KLKEWSLILYGTA 633
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 945 CAKGL--HLYNGRCYSRCPDGTYANEISME----RSSRRRNLTIFSEGSLSKRQDGSLKS 998
C +G H C + CP G YA+E S ++ + + ++ K +
Sbjct: 767 CRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARG 826
Query: 999 SALEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
S + D EP + + C CH+TC TC GP +C+ C
Sbjct: 827 SCIP--DCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 866
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>AB001914-3|BAA21626.1| 962|Homo sapiens PACE4E-II protein.
Length = 962
Score = 565 bits (1395), Expect = e-160
Identities = 273/493 (55%), Positives = 333/493 (67%), Gaps = 15/493 (3%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYM----GRA 547
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+ + + +
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQG 620
Query: 548 SLQEWSLTLYGTS 560
L+EWSL LYGT+
Sbjct: 621 KLKEWSLILYGTA 633
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 945 CAKGL--HLYNGRCYSRCPDGTYANEISME----RSSRRRNLTIFSEGSLSKRQDGSLKS 998
C +G H C + CP G YA+E S ++ + + ++ K +
Sbjct: 754 CRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARG 813
Query: 999 SALEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
S + D EP + + C CH+TC TC GP +C+ C
Sbjct: 814 SCIP--DCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 853
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>AB001914-2|BAA21625.1| 956|Homo sapiens PACE4A-II protein.
Length = 956
Score = 565 bits (1395), Expect = e-160
Identities = 273/493 (55%), Positives = 333/493 (67%), Gaps = 15/493 (3%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYM----GRA 547
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+ + + +
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQG 620
Query: 548 SLQEWSLTLYGTS 560
L+EWSL LYGT+
Sbjct: 621 KLKEWSLILYGTA 633
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 945 CAKGL--HLYNGRCYSRCPDGTYANEISME----RSSRRRNLTIFSEGSLSKRQDGSLKS 998
C +G H C + CP G YA+E S ++ + + ++ K +
Sbjct: 754 CRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARG 813
Query: 999 SALEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
S + D EP + + C CH+TC TC GP +C+ C
Sbjct: 814 SCIP--DCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 853
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>AB001914-1|BAA21624.1| 969|Homo sapiens PACE4A-I protein.
Length = 969
Score = 565 bits (1395), Expect = e-160
Identities = 273/493 (55%), Positives = 333/493 (67%), Gaps = 15/493 (3%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYM----GRA 547
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+ + + +
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQG 620
Query: 548 SLQEWSLTLYGTS 560
L+EWSL LYGT+
Sbjct: 621 KLKEWSLILYGTA 633
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 945 CAKGL--HLYNGRCYSRCPDGTYANEISME----RSSRRRNLTIFSEGSLSKRQDGSLKS 998
C +G H C + CP G YA+E S ++ + + ++ K +
Sbjct: 767 CRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARG 826
Query: 999 SALEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
S + D EP + + C CH+TC TC GP +C+ C
Sbjct: 827 SCIP--DCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 866
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>D28513-1|BAA05871.1| 652|Homo sapiens kexin-like protease protein.
Length = 652
Score = 554 bits (1368), Expect = e-157
Identities = 264/466 (56%), Positives = 319/466 (68%), Gaps = 11/466 (2%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEV 537
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEI 606
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>AB001914-6|BAA21623.1| 623|Homo sapiens PACE4CS protein.
Length = 623
Score = 554 bits (1368), Expect = e-157
Identities = 264/466 (56%), Positives = 319/466 (68%), Gaps = 11/466 (2%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEV 537
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEI 606
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>AB001914-5|BAA21621.1| 652|Homo sapiens PACE4C protein.
Length = 652
Score = 554 bits (1368), Expect = e-157
Identities = 264/466 (56%), Positives = 319/466 (68%), Gaps = 11/466 (2%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQR 436
WRD+QH++V+T+RP L S +W++NG G VSH +G+GL+DA +V AK W VP Q
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQH 500
Query: 437 RCELAAPRPHRMIPPRSAIALQLAVSSC-----PGVNYLEHVQARISLSAARRGDLRITL 491
C A+ + R IP + S+C V YLEHV R S+S RRGDL+I L
Sbjct: 501 MCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYL 560
Query: 492 TSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEV 537
SP+GT LLA R D S+ GF +W FM+VH WGE G+W LE+
Sbjct: 561 VSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEI 606
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>U56387-1|AAC50643.2| 913|Homo sapiens protease PC6 isoform A
protein.
Length = 913
Score = 551 bits (1360), Expect = e-156
Identities = 267/485 (55%), Positives = 322/485 (66%), Gaps = 16/485 (3%)
Query: 101 NDPKWPHMWYLNRGGGL-----DMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYD 155
NDPKWP MWY++ DMN+ AW+ G TG+ +VVTILDDG+E HPDL+ NYD
Sbjct: 127 NDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYD 186
Query: 156 PAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXXMLD 215
AS DVNG D DP PRYD + N+HGTRCAGEVAA ANNS C MLD
Sbjct: 187 ALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLD 246
Query: 216 GDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSI 275
GDVTD+VEA+S+S NPQHV IYSASWGPDDDGKTVDGP L +AF GV GR G GS+
Sbjct: 247 GDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSV 306
Query: 276 FVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINE 335
FVWASGNGG+ D+C+CDGYTNSI+T+SISS E G PWY E+CSSTLA TYSSG +
Sbjct: 307 FVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYD 366
Query: 336 NQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSL 395
+++TTDL CT HTGTSASAP+AAGI ALAL+AN LTWRD+QH++VRT+R L+
Sbjct: 367 KKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN- 425
Query: 396 SGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAI 455
+ +W+ N G VSH +G+GL+DA MV A+ W TVP Q C + R + I P SA+
Sbjct: 426 ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAV 485
Query: 456 ALQLAVSSCPG-----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSS 510
S C VNYLEHV RI+++ RRGDL I LTSP+GT LLA R D S
Sbjct: 486 RSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHS 545
Query: 511 HSGFNSWPFMSVHMWGENPLGEWQLEV----TNEGRYMGRASLQEWSLTLYGTST-PAAK 565
GF +W FM++H WGE G+W LEV + + L+EWSL LYGTS P +
Sbjct: 546 MEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVRPYSP 605
Query: 566 NDPIP 570
+ P
Sbjct: 606 TNEFP 610
Score = 44.4 bits (100), Expect = 0.002
Identities = 17/47 (36%), Positives = 27/47 (57%)
Query: 4 DHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDF 50
D+YHF+H KRS+ + H + + +V W +QQ + R KRD+
Sbjct: 70 DYYHFYHSRTIKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDY 116
Score = 42.3 bits (95), Expect = 0.010
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 956 CYSRCPDGTYAN-EISMERSSRRRNLTIFSEGSLSKRQDG-SLKSSALEALDMEPYANST 1013
C + CPDG+Y + + ++ R T + ++ +DG SL+ S + +
Sbjct: 720 CVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNG 779
Query: 1014 KDPLICLPCHYTCATCAGPHDSQCVSCLD 1042
+D C PCH CATCAG C++C +
Sbjct: 780 QD---CQPCHRFCATCAGAGADGCINCTE 805
>BC012064-1|AAH12064.1| 913|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 913
Score = 551 bits (1360), Expect = e-156
Identities = 267/485 (55%), Positives = 322/485 (66%), Gaps = 16/485 (3%)
Query: 101 NDPKWPHMWYLNRGGGL-----DMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYD 155
NDPKWP MWY++ DMN+ AW+ G TG+ +VVTILDDG+E HPDL+ NYD
Sbjct: 127 NDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYD 186
Query: 156 PAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXXMLD 215
AS DVNG D DP PRYD + N+HGTRCAGEVAA ANNS C MLD
Sbjct: 187 ALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLD 246
Query: 216 GDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSI 275
GDVTD+VEA+S+S NPQHV IYSASWGPDDDGKTVDGP L +AF GV GR G GS+
Sbjct: 247 GDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSV 306
Query: 276 FVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINE 335
FVWASGNGG+ D+C+CDGYTNSI+T+SISS E G PWY E+CSSTLA TYSSG +
Sbjct: 307 FVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYD 366
Query: 336 NQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSL 395
+++TTDL CT HTGTSASAP+AAGI ALAL+AN LTWRD+QH++VRT+R L+
Sbjct: 367 KKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN- 425
Query: 396 SGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAI 455
+ +W+ N G VSH +G+GL+DA MV A+ W TVP Q C + R + I P SA+
Sbjct: 426 ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAV 485
Query: 456 ALQLAVSSCPG-----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSS 510
S C VNYLEHV RI+++ RRGDL I LTSP+GT LLA R D S
Sbjct: 486 RSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHS 545
Query: 511 HSGFNSWPFMSVHMWGENPLGEWQLEV----TNEGRYMGRASLQEWSLTLYGTST-PAAK 565
GF +W FM++H WGE G+W LEV + + L+EWSL LYGTS P +
Sbjct: 546 MEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSP 605
Query: 566 NDPIP 570
+ P
Sbjct: 606 TNEFP 610
Score = 44.4 bits (100), Expect = 0.002
Identities = 17/47 (36%), Positives = 27/47 (57%)
Query: 4 DHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDF 50
D+YHF+H KRS+ + H + + +V W +QQ + R KRD+
Sbjct: 70 DYYHFYHSRTIKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDY 116
Score = 42.3 bits (95), Expect = 0.010
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 956 CYSRCPDGTYAN-EISMERSSRRRNLTIFSEGSLSKRQDG-SLKSSALEALDMEPYANST 1013
C + CPDG+Y + + ++ R T + ++ +DG SL+ S + +
Sbjct: 720 CVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNG 779
Query: 1014 KDPLICLPCHYTCATCAGPHDSQCVSCLD 1042
+D C PCH CATCAG C++C +
Sbjct: 780 QD---CQPCHRFCATCAGAGADGCINCTE 805
>AL359253-2|CAH73743.1| 913|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 913
Score = 551 bits (1360), Expect = e-156
Identities = 267/485 (55%), Positives = 322/485 (66%), Gaps = 16/485 (3%)
Query: 101 NDPKWPHMWYLNRGGGL-----DMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYD 155
NDPKWP MWY++ DMN+ AW+ G TG+ +VVTILDDG+E HPDL+ NYD
Sbjct: 127 NDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYD 186
Query: 156 PAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXXMLD 215
AS DVNG D DP PRYD + N+HGTRCAGEVAA ANNS C MLD
Sbjct: 187 ALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLD 246
Query: 216 GDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSI 275
GDVTD+VEA+S+S NPQHV IYSASWGPDDDGKTVDGP L +AF GV GR G GS+
Sbjct: 247 GDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSV 306
Query: 276 FVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINE 335
FVWASGNGG+ D+C+CDGYTNSI+T+SISS E G PWY E+CSSTLA TYSSG +
Sbjct: 307 FVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYD 366
Query: 336 NQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSL 395
+++TTDL CT HTGTSASAP+AAGI ALAL+AN LTWRD+QH++VRT+R L+
Sbjct: 367 KKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN- 425
Query: 396 SGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAI 455
+ +W+ N G VSH +G+GL+DA MV A+ W TVP Q C + R + I P SA+
Sbjct: 426 ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAV 485
Query: 456 ALQLAVSSCPG-----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSS 510
S C VNYLEHV RI+++ RRGDL I LTSP+GT LLA R D S
Sbjct: 486 RSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHS 545
Query: 511 HSGFNSWPFMSVHMWGENPLGEWQLEV----TNEGRYMGRASLQEWSLTLYGTST-PAAK 565
GF +W FM++H WGE G+W LEV + + L+EWSL LYGTS P +
Sbjct: 546 MEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSP 605
Query: 566 NDPIP 570
+ P
Sbjct: 606 TNEFP 610
Score = 44.4 bits (100), Expect = 0.002
Identities = 17/47 (36%), Positives = 27/47 (57%)
Query: 4 DHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDF 50
D+YHF+H KRS+ + H + + +V W +QQ + R KRD+
Sbjct: 70 DYYHFYHSRTIKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDY 116
Score = 42.3 bits (95), Expect = 0.010
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 956 CYSRCPDGTYAN-EISMERSSRRRNLTIFSEGSLSKRQDG-SLKSSALEALDMEPYANST 1013
C + CPDG+Y + + ++ R T + ++ +DG SL+ S + +
Sbjct: 720 CVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNG 779
Query: 1014 KDPLICLPCHYTCATCAGPHDSQCVSCLD 1042
+D C PCH CATCAG C++C +
Sbjct: 780 QD---CQPCHRFCATCAGAGADGCINCTE 805
>AL359253-1|CAH73742.1| 690|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 690
Score = 551 bits (1360), Expect = e-156
Identities = 267/485 (55%), Positives = 322/485 (66%), Gaps = 16/485 (3%)
Query: 101 NDPKWPHMWYLNRGGGL-----DMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYD 155
NDPKWP MWY++ DMN+ AW+ G TG+ +VVTILDDG+E HPDL+ NYD
Sbjct: 127 NDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYD 186
Query: 156 PAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXXMLD 215
AS DVNG D DP PRYD + N+HGTRCAGEVAA ANNS C MLD
Sbjct: 187 ALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLD 246
Query: 216 GDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSI 275
GDVTD+VEA+S+S NPQHV IYSASWGPDDDGKTVDGP L +AF GV GR G GS+
Sbjct: 247 GDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSV 306
Query: 276 FVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINE 335
FVWASGNGG+ D+C+CDGYTNSI+T+SISS E G PWY E+CSSTLA TYSSG +
Sbjct: 307 FVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYD 366
Query: 336 NQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSL 395
+++TTDL CT HTGTSASAP+AAGI ALAL+AN LTWRD+QH++VRT+R L+
Sbjct: 367 KKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN- 425
Query: 396 SGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAI 455
+ +W+ N G VSH +G+GL+DA MV A+ W TVP Q C + R + I P SA+
Sbjct: 426 ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAV 485
Query: 456 ALQLAVSSCPG-----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSS 510
S C VNYLEHV RI+++ RRGDL I LTSP+GT LLA R D S
Sbjct: 486 RSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHS 545
Query: 511 HSGFNSWPFMSVHMWGENPLGEWQLEV----TNEGRYMGRASLQEWSLTLYGTST-PAAK 565
GF +W FM++H WGE G+W LEV + + L+EWSL LYGTS P +
Sbjct: 546 MEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSP 605
Query: 566 NDPIP 570
+ P
Sbjct: 606 TNEFP 610
Score = 44.4 bits (100), Expect = 0.002
Identities = 17/47 (36%), Positives = 27/47 (57%)
Query: 4 DHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDF 50
D+YHF+H KRS+ + H + + +V W +QQ + R KRD+
Sbjct: 70 DYYHFYHSRTIKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDY 116
>AL353607-2|CAI41233.1| 913|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 913
Score = 551 bits (1360), Expect = e-156
Identities = 267/485 (55%), Positives = 322/485 (66%), Gaps = 16/485 (3%)
Query: 101 NDPKWPHMWYLNRGGGL-----DMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYD 155
NDPKWP MWY++ DMN+ AW+ G TG+ +VVTILDDG+E HPDL+ NYD
Sbjct: 127 NDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYD 186
Query: 156 PAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXXMLD 215
AS DVNG D DP PRYD + N+HGTRCAGEVAA ANNS C MLD
Sbjct: 187 ALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLD 246
Query: 216 GDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSI 275
GDVTD+VEA+S+S NPQHV IYSASWGPDDDGKTVDGP L +AF GV GR G GS+
Sbjct: 247 GDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSV 306
Query: 276 FVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINE 335
FVWASGNGG+ D+C+CDGYTNSI+T+SISS E G PWY E+CSSTLA TYSSG +
Sbjct: 307 FVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYD 366
Query: 336 NQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSL 395
+++TTDL CT HTGTSASAP+AAGI ALAL+AN LTWRD+QH++VRT+R L+
Sbjct: 367 KKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN- 425
Query: 396 SGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAI 455
+ +W+ N G VSH +G+GL+DA MV A+ W TVP Q C + R + I P SA+
Sbjct: 426 ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAV 485
Query: 456 ALQLAVSSCPG-----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSS 510
S C VNYLEHV RI+++ RRGDL I LTSP+GT LLA R D S
Sbjct: 486 RSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHS 545
Query: 511 HSGFNSWPFMSVHMWGENPLGEWQLEV----TNEGRYMGRASLQEWSLTLYGTST-PAAK 565
GF +W FM++H WGE G+W LEV + + L+EWSL LYGTS P +
Sbjct: 546 MEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSP 605
Query: 566 NDPIP 570
+ P
Sbjct: 606 TNEFP 610
Score = 44.4 bits (100), Expect = 0.002
Identities = 17/47 (36%), Positives = 27/47 (57%)
Query: 4 DHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDF 50
D+YHF+H KRS+ + H + + +V W +QQ + R KRD+
Sbjct: 70 DYYHFYHSRTIKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDY 116
Score = 42.3 bits (95), Expect = 0.010
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 956 CYSRCPDGTYAN-EISMERSSRRRNLTIFSEGSLSKRQDG-SLKSSALEALDMEPYANST 1013
C + CPDG+Y + + ++ R T + ++ +DG SL+ S + +
Sbjct: 720 CVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNG 779
Query: 1014 KDPLICLPCHYTCATCAGPHDSQCVSCLD 1042
+D C PCH CATCAG C++C +
Sbjct: 780 QD---CQPCHRFCATCAGAGADGCINCTE 805
>AL353607-1|CAI41232.1| 690|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 690
Score = 551 bits (1360), Expect = e-156
Identities = 267/485 (55%), Positives = 322/485 (66%), Gaps = 16/485 (3%)
Query: 101 NDPKWPHMWYLNRGGGL-----DMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYD 155
NDPKWP MWY++ DMN+ AW+ G TG+ +VVTILDDG+E HPDL+ NYD
Sbjct: 127 NDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYD 186
Query: 156 PAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXXMLD 215
AS DVNG D DP PRYD + N+HGTRCAGEVAA ANNS C MLD
Sbjct: 187 ALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLD 246
Query: 216 GDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSI 275
GDVTD+VEA+S+S NPQHV IYSASWGPDDDGKTVDGP L +AF GV GR G GS+
Sbjct: 247 GDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSV 306
Query: 276 FVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINE 335
FVWASGNGG+ D+C+CDGYTNSI+T+SISS E G PWY E+CSSTLA TYSSG +
Sbjct: 307 FVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYD 366
Query: 336 NQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSL 395
+++TTDL CT HTGTSASAP+AAGI ALAL+AN LTWRD+QH++VRT+R L+
Sbjct: 367 KKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN- 425
Query: 396 SGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAI 455
+ +W+ N G VSH +G+GL+DA MV A+ W TVP Q C + R + I P SA+
Sbjct: 426 ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAV 485
Query: 456 ALQLAVSSCPG-----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSS 510
S C VNYLEHV RI+++ RRGDL I LTSP+GT LLA R D S
Sbjct: 486 RSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHS 545
Query: 511 HSGFNSWPFMSVHMWGENPLGEWQLEV----TNEGRYMGRASLQEWSLTLYGTST-PAAK 565
GF +W FM++H WGE G+W LEV + + L+EWSL LYGTS P +
Sbjct: 546 MEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSP 605
Query: 566 NDPIP 570
+ P
Sbjct: 606 TNEFP 610
Score = 44.4 bits (100), Expect = 0.002
Identities = 17/47 (36%), Positives = 27/47 (57%)
Query: 4 DHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDF 50
D+YHF+H KRS+ + H + + +V W +QQ + R KRD+
Sbjct: 70 DYYHFYHSRTIKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDY 116
>U49114-1|AAA91807.1| 899|Homo sapiens prohormone convertase 5
precursor protein.
Length = 899
Score = 549 bits (1354), Expect = e-155
Identities = 266/485 (54%), Positives = 321/485 (66%), Gaps = 16/485 (3%)
Query: 101 NDPKWPHMWYLNRGGGL-----DMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYD 155
NDPKWP MWY++ DMN+ AW+ G TG+ +VVTILDDG+E HPDL+ NYD
Sbjct: 113 NDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYD 172
Query: 156 PAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXXMLD 215
AS DVNG D DP PRYD + N+HGTRCAGEVAA ANNS C MLD
Sbjct: 173 ALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLD 232
Query: 216 GDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSI 275
GDVTD+VEA+S+S NPQHV IYSASWGPDDDGKTVDGP L +AF GV GR G GS+
Sbjct: 233 GDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSV 292
Query: 276 FVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINE 335
FVWASGNGG+ D+C+CDGYTNSI+T+SISS E G PWY E+CSSTLA TYSSG +
Sbjct: 293 FVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYD 352
Query: 336 NQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSL 395
+++TTDL CT HTGTSASAP+AAGI ALAL+AN LTWRD+QH++VRT+R L+
Sbjct: 353 KKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN- 411
Query: 396 SGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAI 455
+ +W+ N G VSH +G+GL+DA MV A+ W TVP Q C + R + I P SA+
Sbjct: 412 ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAV 471
Query: 456 ALQLAVSSCPG-----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSS 510
S C VNYLEHV I+++ RRGDL I LTSP+GT LLA R D S
Sbjct: 472 RSIYKASGCSDNPNRHVNYLEHVVVAITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHS 531
Query: 511 HSGFNSWPFMSVHMWGENPLGEWQLEV----TNEGRYMGRASLQEWSLTLYGTST-PAAK 565
GF +W FM++H WGE G+W LEV + + L+EWSL LYGTS P +
Sbjct: 532 MEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSP 591
Query: 566 NDPIP 570
+ P
Sbjct: 592 TNEFP 596
Score = 44.4 bits (100), Expect = 0.002
Identities = 17/47 (36%), Positives = 27/47 (57%)
Query: 4 DHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDF 50
D+YHF+H KRS+ + H + + +V W +QQ + R KRD+
Sbjct: 56 DYYHFYHSRTIKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDY 102
Score = 42.3 bits (95), Expect = 0.010
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 956 CYSRCPDGTYAN-EISMERSSRRRNLTIFSEGSLSKRQDG-SLKSSALEALDMEPYANST 1013
C + CPDG+Y + + ++ R T + ++ +DG SL+ S + +
Sbjct: 706 CVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNG 765
Query: 1014 KDPLICLPCHYTCATCAGPHDSQCVSCLD 1042
+D C PCH CATCAG C++C +
Sbjct: 766 QD---CQPCHRFCATCAGAGADGCINCTE 791
>M90753-1|AAA59918.1| 753|Homo sapiens PC1 protein.
Length = 753
Score = 539 bits (1330), Expect = e-152
Identities = 254/477 (53%), Positives = 327/477 (68%), Gaps = 14/477 (2%)
Query: 99 ILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDDGLETDHPDLVA 152
+ NDP W WYL LD++VIP W++GITG+GVV+T+LDDGLE +H D+ A
Sbjct: 120 LFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYA 179
Query: 153 NYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXX 212
NYDP ASYD N D DP PRYD + N+HGTRCAGE+A ANN C
Sbjct: 180 NYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIR 239
Query: 213 MLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGK 272
MLDG VTD +EA S+ NP HVDIYSASWGP+DDGKTV+GPG LA +AF GV +GR GK
Sbjct: 240 MLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGK 299
Query: 273 GSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGA 332
GSIFVWASGNGG++ DNC+CDGYT+SI+T+SISSA+++G PWY+EKCSSTLA +YSSG
Sbjct: 300 GSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGD 359
Query: 333 INENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPER 392
+ ++ + DLH+ CT HTGTSASAPLAAGI ALAL+AN +LTWRDMQH+VV T+ +
Sbjct: 360 YTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDP 419
Query: 393 LSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLA--KTWRTVPPQRRCELA-APRPHRMI 449
L+ + W+ NG G V+ FG+GLL+A +V LA +TWR+VP ++ C + R +
Sbjct: 420 LANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRAL 479
Query: 450 PPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPR 505
+ +++ +C G + LEHVQ ++ +RRGDL +TLTS AGT+ LLA R
Sbjct: 480 KANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAER 539
Query: 506 PHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTN-EGRYMGRASLQEWSLTLYGTST 561
D+S +GF +W FMSVH WGENP+G W L +T+ GR + W L L+GTS+
Sbjct: 540 ERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSS 596
Score = 39.5 bits (88), Expect = 0.068
Identities = 20/46 (43%), Positives = 25/46 (54%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
++HY F H++ +RS A RL D RV WAEQQ R KR
Sbjct: 65 ENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKR 110
>BC130295-1|AAI30296.1| 753|Homo sapiens proprotein convertase
subtilisin/kexin type 1 protein.
Length = 753
Score = 539 bits (1330), Expect = e-152
Identities = 254/477 (53%), Positives = 327/477 (68%), Gaps = 14/477 (2%)
Query: 99 ILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDDGLETDHPDLVA 152
+ NDP W WYL LD++VIP W++GITG+GVV+T+LDDGLE +H D+ A
Sbjct: 120 LFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYA 179
Query: 153 NYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXX 212
NYDP ASYD N D DP PRYD + N+HGTRCAGE+A ANN C
Sbjct: 180 NYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIR 239
Query: 213 MLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGK 272
MLDG VTD +EA S+ NP HVDIYSASWGP+DDGKTV+GPG LA +AF GV +GR GK
Sbjct: 240 MLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGK 299
Query: 273 GSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGA 332
GSIFVWASGNGG++ DNC+CDGYT+SI+T+SISSA+++G PWY+EKCSSTLA +YSSG
Sbjct: 300 GSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGD 359
Query: 333 INENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPER 392
+ ++ + DLH+ CT HTGTSASAPLAAGI ALAL+AN +LTWRDMQH+VV T+ +
Sbjct: 360 YTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDP 419
Query: 393 LSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLA--KTWRTVPPQRRCELA-APRPHRMI 449
L+ + W+ NG G V+ FG+GLL+A +V LA +TWR+VP ++ C + R +
Sbjct: 420 LANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRAL 479
Query: 450 PPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPR 505
+ +++ +C G + LEHVQ ++ +RRGDL +TLTS AGT+ LLA R
Sbjct: 480 KANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAER 539
Query: 506 PHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTN-EGRYMGRASLQEWSLTLYGTST 561
D+S +GF +W FMSVH WGENP+G W L +T+ GR + W L L+GTS+
Sbjct: 540 ERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSS 596
Score = 39.5 bits (88), Expect = 0.068
Identities = 20/46 (43%), Positives = 25/46 (54%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
++HY F H++ +RS A RL D RV WAEQQ R KR
Sbjct: 65 ENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKR 110
>X64810-1|CAA46031.1| 753|Homo sapiens PC1/PC3 protein.
Length = 753
Score = 537 bits (1326), Expect = e-152
Identities = 253/477 (53%), Positives = 326/477 (68%), Gaps = 14/477 (2%)
Query: 99 ILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDDGLETDHPDLVA 152
+ NDP W WYL LD++VIP W++GITG+GVV+T+LDDGLE +H D+ A
Sbjct: 120 LFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYA 179
Query: 153 NYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXX 212
NYDP ASYD N D DP PRYD + N+HGTRCAGE+A ANN C
Sbjct: 180 NYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIR 239
Query: 213 MLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGK 272
MLDG VTD +EA S+ NP HVDIYSASWGP+DDGKTV+GPG LA +AF GV +GR GK
Sbjct: 240 MLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGK 299
Query: 273 GSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGA 332
GSIFVWASGNGG++ DNC+CDGYT+SI+T+SISSA+++G PWY+EKCSSTLA +YS G
Sbjct: 300 GSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSGGD 359
Query: 333 INENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPER 392
+ ++ + DLH+ CT HTGTSASAPLAAGI ALAL+AN +LTWRDMQH+VV T+ +
Sbjct: 360 YTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDP 419
Query: 393 LSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLA--KTWRTVPPQRRCELA-APRPHRMI 449
L+ + W+ NG G V+ FG+GLL+A +V LA +TWR+VP ++ C + R +
Sbjct: 420 LANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRAL 479
Query: 450 PPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPR 505
+ +++ +C G + LEHVQ ++ +RRGDL +TLTS AGT+ LLA R
Sbjct: 480 KANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAER 539
Query: 506 PHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTN-EGRYMGRASLQEWSLTLYGTST 561
D+S +GF +W FMSVH WGENP+G W L +T+ GR + W L L+GTS+
Sbjct: 540 ERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSS 596
Score = 39.5 bits (88), Expect = 0.068
Identities = 20/46 (43%), Positives = 25/46 (54%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
++HY F H++ +RS A RL D RV WAEQQ R KR
Sbjct: 65 ENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKR 110
>D28514-1|BAA05872.1| 497|Homo sapiens kexin-like protease protein.
Length = 497
Score = 537 bits (1325), Expect = e-152
Identities = 256/440 (58%), Positives = 306/440 (69%), Gaps = 11/440 (2%)
Query: 108 MWYLNRGGG-----LDMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYDPAASYDV 162
MWYL+ G +MNV AW+ G TG+ VVVTILDDG+E +HPDL NYD ASYDV
Sbjct: 1 MWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDV 60
Query: 163 NGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXXMLDGDVTDVV 222
NG D DP PRYD + N+HGTRCAGEVAA+ANNS C MLDGDVTDVV
Sbjct: 61 NGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVV 120
Query: 223 EARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSIFVWASGN 282
EA+SL + P ++DIYSASWGPDDDGKTVDGPG LA +AF G+ KGR G GSIFVWASGN
Sbjct: 121 EAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGN 180
Query: 283 GGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINENQVVTTD 342
GG+E D C+CDGYTNSI+T+S+SSATE G PWY E+C+STLA TYSSGA E ++VTTD
Sbjct: 181 GGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTD 240
Query: 343 LHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSLSGEWRIN 402
L CT GHTGTS SAP+ AGI ALAL+AN LTWRD+QH++V+T+RP L S +W++N
Sbjct: 241 LRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVN 299
Query: 403 GVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAIALQLAVS 462
G G VSH +G+GL+DA +V AK W VP Q C A+ + R IP + S
Sbjct: 300 GAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTS 359
Query: 463 SC-----PGVNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSSHSGFNSW 517
+C V YLEHV R S+S RRGDL+I L SP+GT LLA R D S+ GF +W
Sbjct: 360 ACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNW 419
Query: 518 PFMSVHMWGENPLGEWQLEV 537
FM+VH WGE G+W LE+
Sbjct: 420 EFMTVHCWGEKAEGQWTLEI 439
>AB001914-8|BAA21622.1| 497|Homo sapiens PACE4D protein.
Length = 497
Score = 537 bits (1325), Expect = e-152
Identities = 256/440 (58%), Positives = 306/440 (69%), Gaps = 11/440 (2%)
Query: 108 MWYLNRGGG-----LDMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYDPAASYDV 162
MWYL+ G +MNV AW+ G TG+ VVVTILDDG+E +HPDL NYD ASYDV
Sbjct: 1 MWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDV 60
Query: 163 NGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXXMLDGDVTDVV 222
NG D DP PRYD + N+HGTRCAGEVAA+ANNS C MLDGDVTDVV
Sbjct: 61 NGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVV 120
Query: 223 EARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSIFVWASGN 282
EA+SL + P ++DIYSASWGPDDDGKTVDGPG LA +AF G+ KGR G GSIFVWASGN
Sbjct: 121 EAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGN 180
Query: 283 GGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINENQVVTTD 342
GG+E D C+CDGYTNSI+T+S+SSATE G PWY E+C+STLA TYSSGA E ++VTTD
Sbjct: 181 GGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTD 240
Query: 343 LHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSLSGEWRIN 402
L CT GHTGTS SAP+ AGI ALAL+AN LTWRD+QH++V+T+RP L S +W++N
Sbjct: 241 LRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKAS-DWKVN 299
Query: 403 GVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAIALQLAVS 462
G G VSH +G+GL+DA +V AK W VP Q C A+ + R IP + S
Sbjct: 300 GAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTS 359
Query: 463 SC-----PGVNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSSHSGFNSW 517
+C V YLEHV R S+S RRGDL+I L SP+GT LLA R D S+ GF +W
Sbjct: 360 ACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNW 419
Query: 518 PFMSVHMWGENPLGEWQLEV 537
FM+VH WGE G+W LE+
Sbjct: 420 EFMTVHCWGEKAEGQWTLEI 439
>AB208874-1|BAD92111.1| 724|Homo sapiens proprotein convertase
subtilisin/kexin type 1 preproprotein variant protein.
Length = 724
Score = 537 bits (1324), Expect = e-151
Identities = 253/477 (53%), Positives = 326/477 (68%), Gaps = 14/477 (2%)
Query: 99 ILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDDGLETDHPDLVA 152
+ NDP W WYL LD++VIP W++GITG+GVV+T+LDDGLE +H D+ A
Sbjct: 91 LFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYA 150
Query: 153 NYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXX 212
NYDP ASYD N D DP PRYD + N+HGTRCAGE+A ANN C
Sbjct: 151 NYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIR 210
Query: 213 MLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGK 272
MLDG VTD +EA S+ NP HVDIYSASWGP+DDGKTV+GPG LA +AF GV +GR GK
Sbjct: 211 MLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGK 270
Query: 273 GSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGA 332
GSIFVWASGNGG++ DNC+CDGYT+SI+T+SISSA+++G PWY+EKCSSTLA +YSSG
Sbjct: 271 GSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGD 330
Query: 333 INENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPER 392
+ ++ + DLH+ CT HTGTSASAPLAAGI ALAL+AN +LTWRDMQH+VV T+ +
Sbjct: 331 YTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDP 390
Query: 393 LSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLA--KTWRTVPPQRRCELA-APRPHRMI 449
L+ + W+ NG G V+ G+GLL+A +V LA +TWR+VP ++ C + R +
Sbjct: 391 LANNPGWKKNGAGLMVNSRIGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRAL 450
Query: 450 PPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPR 505
+ +++ +C G + LEHVQ ++ +RRGDL +TLTS AGT+ LLA R
Sbjct: 451 KANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAER 510
Query: 506 PHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTN-EGRYMGRASLQEWSLTLYGTST 561
D+S +GF +W FMSVH WGENP+G W L +T+ GR + W L L+GTS+
Sbjct: 511 ERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSS 567
Score = 39.5 bits (88), Expect = 0.068
Identities = 20/46 (43%), Positives = 25/46 (54%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
++HY F H++ +RS A RL D RV WAEQQ R KR
Sbjct: 36 ENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKR 81
>D73407-1|BAA11133.1| 753|Homo sapiens prohormone convertase 3
protein.
Length = 753
Score = 534 bits (1318), Expect = e-151
Identities = 252/477 (52%), Positives = 326/477 (68%), Gaps = 14/477 (2%)
Query: 99 ILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDDGLETDHPDLVA 152
+ NDP W WYL LD++VIP W++GITG+GVV+T+LDDGLE +H D+ A
Sbjct: 120 LFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYA 179
Query: 153 NYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXXXXX 212
NYDP ASYD N D DP PRYD + N+HGTRCAGE+A ANN C
Sbjct: 180 NYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIR 239
Query: 213 MLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGK 272
MLDG VTD +EA S+ NP HVDIYSASWGP+DDGKTV+GPG LA +AF GV +GR GK
Sbjct: 240 MLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGK 299
Query: 273 GSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGA 332
GSIFVWASGNGG++ DNC+CDGYT+SI+T+SISSA+++G PWY+EKCSSTLA +YSSG
Sbjct: 300 GSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGD 359
Query: 333 INENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPER 392
+ ++ + D+ + CT HTGTSASAPLAAGI ALAL+AN +LTWRDMQH+VV T+ +
Sbjct: 360 YTDQRITSADVDNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDP 419
Query: 393 LSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLA--KTWRTVPPQRRCELA-APRPHRMI 449
L+ + W+ NG G V+ FG+GLL+A +V LA +TWR+VP ++ C + R +
Sbjct: 420 LANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRAL 479
Query: 450 PPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPR 505
+ +++ +C G + LEHVQ ++ +RRGDL +TLTS AGT+ LLA R
Sbjct: 480 KANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAER 539
Query: 506 PHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTN-EGRYMGRASLQEWSLTLYGTST 561
D+S +GF +W FMSVH WGENP+G W L +T+ GR + W L L+GTS+
Sbjct: 540 ERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSS 596
Score = 39.5 bits (88), Expect = 0.068
Identities = 20/46 (43%), Positives = 25/46 (54%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
++HY F H++ +RS A RL D RV WAEQQ R KR
Sbjct: 65 ENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKR 110
>BC040546-1|AAH40546.1| 619|Homo sapiens PCSK2 protein protein.
Length = 619
Score = 481 bits (1187), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 149
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 150 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 209
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 210 VAYNSKVAGIRMLDQQFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 269
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 270 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 328
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 329 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 388
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 389 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 448
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 449 CVGGSVQDPEKIPSTGELVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 508
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 509 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 568
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 569 TLMLHGTQS 577
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 48 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 98
>M95971-1|AAA59919.1| 638|Homo sapiens neuroendocrine convertase 2
protein.
Length = 638
Score = 481 bits (1186), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 168
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 169 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 228
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 229 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 288
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 289 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 347
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 348 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 407
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 408 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 467
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 468 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 527
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 528 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 587
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 588 TLMLHGTQS 596
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 67 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 117
>BC005815-1|AAH05815.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 481 bits (1186), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 168
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 169 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 228
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 229 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 288
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 289 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 347
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 348 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 407
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 408 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 467
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 468 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 527
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 528 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 587
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 588 TLMLHGTQS 596
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 67 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 117
>AL359511-3|CAC34957.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 481 bits (1186), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 149
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 150 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 209
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 210 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 269
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 270 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 328
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 329 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 388
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 389 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 448
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 449 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 508
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 509 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 568
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 569 TLMLHGTQS 577
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 48 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 98
>AL359511-2|CAI20085.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 481 bits (1186), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 168
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 169 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 228
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 229 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 288
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 289 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 347
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 348 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 407
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 408 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 467
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 468 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 527
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 528 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 587
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 588 TLMLHGTQS 596
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 67 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 117
>AL121779-2|CAB96732.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 481 bits (1186), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 149
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 150 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 209
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 210 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 269
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 270 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 328
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 329 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 388
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 389 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 448
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 449 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 508
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 509 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 568
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 569 TLMLHGTQS 577
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 48 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 98
>AL121779-1|CAI19155.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 481 bits (1186), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 168
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 169 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 228
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 229 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 288
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 289 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 347
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 348 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 407
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 408 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 467
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 468 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 527
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 528 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 587
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 588 TLMLHGTQS 596
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 67 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 117
>AL031675-2|CAA21069.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 481 bits (1186), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 149
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 150 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 209
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 210 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 269
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 270 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 328
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 329 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 388
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 389 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 448
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 449 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 508
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 509 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 568
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 569 TLMLHGTQS 577
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 48 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 98
>AL031675-1|CAI22648.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 481 bits (1186), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 168
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 169 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 228
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 229 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 288
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 289 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 347
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 348 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 407
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 408 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 467
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 468 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 527
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 528 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 587
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 588 TLMLHGTQS 596
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 67 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 117
>AL031664-3|CAB89428.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 481 bits (1186), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 149
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 150 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 209
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 210 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 269
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 270 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 328
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 329 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 388
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 389 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 448
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 449 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 508
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 509 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 568
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 569 TLMLHGTQS 577
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 48 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 98
>AL031664-2|CAI21690.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 481 bits (1186), Expect = e-135
Identities = 242/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 168
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 169 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 228
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP L +A
Sbjct: 229 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQA 288
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 289 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 347
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 348 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 407
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 408 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 467
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 468 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 527
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 528 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 587
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 588 TLMLHGTQS 596
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 67 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 117
>J05252-1|AAA60032.1| 638|Homo sapiens endoprotease protein.
Length = 638
Score = 479 bits (1182), Expect = e-134
Identities = 241/489 (49%), Positives = 312/489 (63%), Gaps = 16/489 (3%)
Query: 88 RGRTRSADLKFILNDPKWPHMWYLNRGG------GLDMNVIPAWREGITGRGVVVTILDD 141
RG ++ +NDP + WYL G GLD+NV AW G TG+GV + I+DD
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDD 168
Query: 142 GLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXX 201
G++ HPDL +NY+ ASYD + DP P PRY N HGTRCAGEV+A ANN++C
Sbjct: 169 GIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVG 228
Query: 202 XXXXXXXXXXXMLDGD-VTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRA 260
MLD +TD++EA S+S PQ +DIYSASWGP D+GKTVDGP + +A
Sbjct: 229 VAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRDVTLQA 288
Query: 261 FIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKC 320
+GV KGR GKGSI+VWASG+GG +D+CNCDGY +S+WT+SI+SA G Y E C
Sbjct: 289 MADGVNKGRGGKGSIYVWASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESC 347
Query: 321 SSTLAATYSSGAIN--ENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWR 378
SSTLA+T+S+G E V TTDL+ +CT H+GTSA+AP AAG+ ALAL+AN LTWR
Sbjct: 348 SSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWR 407
Query: 379 DMQHIVVRTARPERL-SLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRR 437
DMQH+ V T++ +L +WR NGVG +H FGYG+LDA MV++AK W+TVP +
Sbjct: 408 DMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFH 467
Query: 438 CELAAPRPHRMIPPRSAIALQLAVSSCPG----VNYLEHVQARISLSAARRGDLRITLTS 493
C + + IP + L L +C G V YLEHVQA I+++A RRGDL I +TS
Sbjct: 468 CVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTS 527
Query: 494 PAGTNVTLLAPRPH-DSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEW 552
P GT LL+ RP D S GF+ WPFM+ H WGE+ G W LE+ G + L+EW
Sbjct: 528 PMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEW 587
Query: 553 SLTLYGTST 561
+L L+GT +
Sbjct: 588 TLMLHGTQS 596
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/51 (39%), Positives = 29/51 (56%)
Query: 6 YHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTL 56
YHF+H L K + H +LE D RV+ A QQ+ RKKR ++ I+ +
Sbjct: 67 YHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEI 117
>AB001914-7|BAA21620.1| 487|Homo sapiens PACE4B protein.
Length = 487
Score = 438 bits (1079), Expect = e-122
Identities = 202/329 (61%), Positives = 241/329 (73%), Gaps = 6/329 (1%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 201
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 202 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 261
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 262 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 321
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 322 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 381
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLT 376
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+AN LT
Sbjct: 382 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLT 441
Query: 377 WRDMQHIVVRTARPERLSLSGEWRINGVG 405
WRD+QH++V+T+RP L S +W++NG G
Sbjct: 442 WRDVQHLLVKTSRPAHLKAS-DWKVNGAG 469
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 149
>U40623-1|AAC50417.1| 785|Homo sapiens PC8 precursor protein.
Length = 785
Score = 413 bits (1016), Expect = e-114
Identities = 218/480 (45%), Positives = 277/480 (57%), Gaps = 13/480 (2%)
Query: 92 RSADLKFILNDPKWPHMWYLN--RGGGLDMNVIPAWREGITGRGVVVTILDDGLETDHPD 149
R A NDPK+P W+LN R G D+NV W +TGRGV V ++DDG+E D
Sbjct: 137 RRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQD 196
Query: 150 LVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXX 209
+ NY P SYD+N DPDP P DV + N HGTRCAGE+AA NNS C
Sbjct: 197 IAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIA 256
Query: 210 XXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGR 269
+LDG +TD +EA + + + Q DIYS SWGPDDDGKTVDGP L A GV GR
Sbjct: 257 GIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGR 316
Query: 270 NGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYS 329
G GSIFV ASGNGG+ +DNCN DGY NSI+T++I + E G +P+Y+E+C+S LA T+S
Sbjct: 317 QGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFS 376
Query: 330 SGAINENQVVTTDLH----HSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVV 385
G +VTTD CT GHTGTSA+APLAAG+ AL LQ LTWRD+QHI+V
Sbjct: 377 GGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIV 436
Query: 386 RTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRP 445
TA EW N G + SH G+GLL+A +V AK W +VP +
Sbjct: 437 FTATRYE-DRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKE 495
Query: 446 HRMIP--PRSAIAL---QLAVSSCPGVNYLEHVQARISLSAARRGDLRITLTSPAGTNVT 500
++ IP PRS L G+ LEHV +S++ RRG L + L P+G
Sbjct: 496 NKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSL 555
Query: 501 LLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRAS-LQEWSLTLYGT 559
+ APR DS +GFN W F +V WGE G ++L + + G + L++W LTLYG+
Sbjct: 556 IGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESFQVGILRQWQLTLYGS 615
>U33849-1|AAB03087.1| 785|Homo sapiens lymphoma proprotein
convertase protein.
Length = 785
Score = 413 bits (1016), Expect = e-114
Identities = 218/480 (45%), Positives = 277/480 (57%), Gaps = 13/480 (2%)
Query: 92 RSADLKFILNDPKWPHMWYLN--RGGGLDMNVIPAWREGITGRGVVVTILDDGLETDHPD 149
R A NDPK+P W+LN R G D+NV W +TGRGV V ++DDG+E D
Sbjct: 137 RRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQD 196
Query: 150 LVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXX 209
+ NY P SYD+N DPDP P DV + N HGTRCAGE+AA NNS C
Sbjct: 197 IAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIA 256
Query: 210 XXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGR 269
+LDG +TD +EA + + + Q DIYS SWGPDDDGKTVDGP L A GV GR
Sbjct: 257 GIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGR 316
Query: 270 NGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYS 329
G GSIFV ASGNGG+ +DNCN DGY NSI+T++I + E G +P+Y+E+C+S LA T+S
Sbjct: 317 QGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFS 376
Query: 330 SGAINENQVVTTDLH----HSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVV 385
G +VTTD CT GHTGTSA+APLAAG+ AL LQ LTWRD+QHI+V
Sbjct: 377 GGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIV 436
Query: 386 RTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRP 445
TA EW N G + SH G+GLL+A +V AK W +VP +
Sbjct: 437 FTATRYE-DRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKE 495
Query: 446 HRMIP--PRSAIAL---QLAVSSCPGVNYLEHVQARISLSAARRGDLRITLTSPAGTNVT 500
++ IP PRS L G+ LEHV +S++ RRG L + L P+G
Sbjct: 496 NKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSL 555
Query: 501 LLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRAS-LQEWSLTLYGT 559
+ APR DS +GFN W F +V WGE G ++L + + G + L++W LTLYG+
Sbjct: 556 IGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESFQVGILRQWQLTLYGS 615
>BT006870-1|AAP35516.1| 785|Homo sapiens proprotein convertase
subtilisin/kexin type 7 protein.
Length = 785
Score = 413 bits (1016), Expect = e-114
Identities = 218/480 (45%), Positives = 277/480 (57%), Gaps = 13/480 (2%)
Query: 92 RSADLKFILNDPKWPHMWYLN--RGGGLDMNVIPAWREGITGRGVVVTILDDGLETDHPD 149
R A NDPK+P W+LN R G D+NV W +TGRGV V ++DDG+E D
Sbjct: 137 RRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQD 196
Query: 150 LVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXX 209
+ NY P SYD+N DPDP P DV + N HGTRCAGE+AA NNS C
Sbjct: 197 IAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIA 256
Query: 210 XXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGR 269
+LDG +TD +EA + + + Q DIYS SWGPDDDGKTVDGP L A GV GR
Sbjct: 257 GIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGR 316
Query: 270 NGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYS 329
G GSIFV ASGNGG+ +DNCN DGY NSI+T++I + E G +P+Y+E+C+S LA T+S
Sbjct: 317 QGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFS 376
Query: 330 SGAINENQVVTTDLH----HSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVV 385
G +VTTD CT GHTGTSA+APLAAG+ AL LQ LTWRD+QHI+V
Sbjct: 377 GGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIV 436
Query: 386 RTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRP 445
TA EW N G + SH G+GLL+A +V AK W +VP +
Sbjct: 437 FTATRYE-DRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKE 495
Query: 446 HRMIP--PRSAIAL---QLAVSSCPGVNYLEHVQARISLSAARRGDLRITLTSPAGTNVT 500
++ IP PRS L G+ LEHV +S++ RRG L + L P+G
Sbjct: 496 NKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSL 555
Query: 501 LLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRAS-LQEWSLTLYGT 559
+ APR DS +GFN W F +V WGE G ++L + + G + L++W LTLYG+
Sbjct: 556 IGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESFQVGILRQWQLTLYGS 615
>BC010696-1|AAH10696.1| 785|Homo sapiens proprotein convertase
subtilisin/kexin type 7 protein.
Length = 785
Score = 413 bits (1016), Expect = e-114
Identities = 218/480 (45%), Positives = 277/480 (57%), Gaps = 13/480 (2%)
Query: 92 RSADLKFILNDPKWPHMWYLN--RGGGLDMNVIPAWREGITGRGVVVTILDDGLETDHPD 149
R A NDPK+P W+LN R G D+NV W +TGRGV V ++DDG+E D
Sbjct: 137 RRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQD 196
Query: 150 LVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXX 209
+ NY P SYD+N DPDP P DV + N HGTRCAGE+AA NNS C
Sbjct: 197 IAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIA 256
Query: 210 XXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGR 269
+LDG +TD +EA + + + Q DIYS SWGPDDDGKTVDGP L A GV GR
Sbjct: 257 GIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGR 316
Query: 270 NGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYS 329
G GSIFV ASGNGG+ +DNCN DGY NSI+T++I + E G +P+Y+E+C+S LA T+S
Sbjct: 317 QGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFS 376
Query: 330 SGAINENQVVTTDLH----HSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVV 385
G +VTTD CT GHTGTSA+APLAAG+ AL LQ LTWRD+QHI+V
Sbjct: 377 GGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIV 436
Query: 386 RTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRP 445
TA EW N G + SH G+GLL+A +V AK W +VP +
Sbjct: 437 FTATRYE-DRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKE 495
Query: 446 HRMIP--PRSAIAL---QLAVSSCPGVNYLEHVQARISLSAARRGDLRITLTSPAGTNVT 500
++ IP PRS L G+ LEHV +S++ RRG L + L P+G
Sbjct: 496 NKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSL 555
Query: 501 LLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRAS-LQEWSLTLYGT 559
+ APR DS +GFN W F +V WGE G ++L + + G + L++W LTLYG+
Sbjct: 556 IGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESFQVGILRQWQLTLYGS 615
>AK222907-1|BAD96627.1| 785|Homo sapiens proprotein convertase
subtilisin/kexin type 7 preproprotein variant protein.
Length = 785
Score = 409 bits (1008), Expect = e-113
Identities = 217/480 (45%), Positives = 276/480 (57%), Gaps = 13/480 (2%)
Query: 92 RSADLKFILNDPKWPHMWYLN--RGGGLDMNVIPAWREGITGRGVVVTILDDGLETDHPD 149
R A NDPK+P W+LN R G D+NV W +TGRGV V ++DDG+E D
Sbjct: 137 RRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQD 196
Query: 150 LVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXX 209
+ NY P SYD+N DPDP P DV + N GTRCAGE+AA NNS C
Sbjct: 197 IAPNYSPEGSYDLNSNDPDPMPHPDVENGNHRGTRCAGEIAAVPNNSFCAVGVAYGSRIA 256
Query: 210 XXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGR 269
+LDG +TD +EA + + + Q DIYS SWGPDDDGKTVDGP L A GV GR
Sbjct: 257 GIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGR 316
Query: 270 NGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYS 329
G GSIFV ASGNGG+ +DNCN DGY NSI+T++I + E G +P+Y+E+C+S LA T+S
Sbjct: 317 QGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFS 376
Query: 330 SGAINENQVVTTDLH----HSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVV 385
G +VTTD CT GHTGTSA+APLAAG+ AL LQ LTWRD+QHI+V
Sbjct: 377 GGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIV 436
Query: 386 RTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRP 445
TA EW N G + SH G+GLL+A +V AK W +VP +
Sbjct: 437 FTATRYE-DRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKE 495
Query: 446 HRMIP--PRSAIAL---QLAVSSCPGVNYLEHVQARISLSAARRGDLRITLTSPAGTNVT 500
++ IP PRS L G+ LEHV +S++ RRG L + L P+G
Sbjct: 496 NKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSL 555
Query: 501 LLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRAS-LQEWSLTLYGT 559
+ APR DS +GFN W F +V WGE G ++L + + G + L++W LTLYG+
Sbjct: 556 IGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESFQVGILRQWQLTLYGS 615
>AM491522-1|CAM33226.1| 357|Homo sapiens proprotein convertase
subtilisin/kexin type 6 protein.
Length = 357
Score = 394 bits (971), Expect = e-109
Identities = 184/295 (62%), Positives = 215/295 (72%), Gaps = 5/295 (1%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 63 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 122
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 123 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 182
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 183 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 242
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 243 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 302
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQA 371
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+A
Sbjct: 303 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEA 357
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 25 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 70
>AB208955-1|BAD92192.1| 800|Homo sapiens paired basic amino acid
cleaving system 4 isoform a preproprotein variant
protein.
Length = 800
Score = 394 bits (971), Expect = e-109
Identities = 184/295 (62%), Positives = 215/295 (72%), Gaps = 5/295 (1%)
Query: 82 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGG-----LDMNVIPAWREGITGRGVVV 136
E+ R++ + RS NDP W +MWYL+ G +MNV AW+ G TG+ VVV
Sbjct: 47 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVV 106
Query: 137 TILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNS 196
TILDDG+E +HPDL NYD ASYDVNG D DP PRYD + N+HGTRCAGEVAA+ANNS
Sbjct: 107 TILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNS 166
Query: 197 LCXXXXXXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLL 256
C MLDGDVTDVVEA+SL + P ++DIYSASWGPDDDGKTVDGPG L
Sbjct: 167 YCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRL 226
Query: 257 ATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWY 316
A +AF G+ KGR G GSIFVWASGNGG+E D C+CDGYTNSI+T+S+SSATE G PWY
Sbjct: 227 AKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWY 286
Query: 317 SEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQA 371
E+C+STLA TYSSGA E ++VTTDL CT GHTGTS SAP+ AGI ALAL+A
Sbjct: 287 LEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEA 341
Score = 97.9 bits (233), Expect = 2e-19
Identities = 52/112 (46%), Positives = 67/112 (59%), Gaps = 4/112 (3%)
Query: 453 SAIALQLAVSSCPGVNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSSHS 512
+A+ A S V YLEHV R S+S RRGDL+I L SP+GT LLA R D S+
Sbjct: 353 TALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNE 412
Query: 513 GFNSWPFMSVHMWGENPLGEWQLEVTNEGRYM----GRASLQEWSLTLYGTS 560
GF +W FM+VH WGE G+W LE+ + + + L+EWSL LYGT+
Sbjct: 413 GFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGKLKEWSLILYGTA 464
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 945 CAKGL--HLYNGRCYSRCPDGTYANEISME----RSSRRRNLTIFSEGSLSKRQDGSLKS 998
C +G H C + CP G YA+E S ++ + + ++ K +
Sbjct: 598 CRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARG 657
Query: 999 SALEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
S + D EP + + C CH+TC TC GP +C+ C
Sbjct: 658 SCIP--DCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 697
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 3 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 48
+D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 9 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 54
>BC006357-1|AAH06357.1| 591|Homo sapiens PCSK7 protein protein.
Length = 591
Score = 373 bits (917), Expect = e-102
Identities = 199/429 (46%), Positives = 248/429 (57%), Gaps = 12/429 (2%)
Query: 92 RSADLKFILNDPKWPHMWYLN--RGGGLDMNVIPAWREGITGRGVVVTILDDGLETDHPD 149
R A NDPK+P W+LN R G D+NV W +TGRGV V ++DDG+E D
Sbjct: 137 RRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQD 196
Query: 150 LVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXXXXXXXXX 209
+ NY P SYD+N DPDP P DV + N HGTRCAGE+AA NNS C
Sbjct: 197 IAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIA 256
Query: 210 XXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGR 269
+LDG +TD +EA + + + Q DIYS SWGPDDDGKTVDGP L A GV GR
Sbjct: 257 GIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGR 316
Query: 270 NGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYS 329
G GSIFV ASGNGG+ +DNCN DGY NSI+T++I + E G +P+Y+E+C+S LA T+S
Sbjct: 317 QGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFS 376
Query: 330 SGAINENQVVTTDLH----HSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVV 385
G +VTTD CT GHTGTSA+APLAAG+ AL LQ LTWRD+QHI+V
Sbjct: 377 GGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIV 436
Query: 386 RTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRP 445
TA EW N G + SH G+GLL+A +V AK W +VP +
Sbjct: 437 FTATRYE-DRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKE 495
Query: 446 HRMIP--PRSAIAL---QLAVSSCPGVNYLEHVQARISLSAARRGDLRITLTSPAGTNVT 500
++ IP PRS L G+ LEHV +S++ RRG L + L P+G
Sbjct: 496 NKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSL 555
Query: 501 LLAPRPHDS 509
+ APR DS
Sbjct: 556 IGAPRSMDS 564
>X04329-1|CAA27860.1| 499|Homo sapiens furin protein.
Length = 499
Score = 348 bits (855), Expect = 8e-95
Identities = 172/313 (54%), Positives = 215/313 (68%), Gaps = 10/313 (3%)
Query: 283 GGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINENQVVTTD 342
GG+EHD+CNCDGYTNSI+TLSISSAT+ G+VPWYSE CSSTLA TYSSG NE Q+VTTD
Sbjct: 1 GGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTD 60
Query: 343 LHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSLSGEWRIN 402
L CT HTGTSASAPLAAGI AL L+AN++LTWRDMQH+VV+T++P L+ + +W N
Sbjct: 61 LRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN-ANDWATN 119
Query: 403 GVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAIALQLAVS 462
GVGR VSHS+GYGLLDA MV LA+ W TV PQR+C + + I R + ++ V+
Sbjct: 120 GVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKR--LEVRKTVT 177
Query: 463 SCPG----VNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSSHSGFNSWP 518
+C G + LEH QAR++LS RRGDL I L SP GT TLLA RPHD S GFN W
Sbjct: 178 ACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWA 237
Query: 519 FMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEWSLTLYGTSTPAAKNDPIPFRNPIIRN 578
FM+ H W E+P GEW LE+ N +L +++L LYGT A + P+P + +
Sbjct: 238 FMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGT---APEGLPVPPESSGCKT 294
Query: 579 KGNASRPVVLQAG 591
++ VV + G
Sbjct: 295 LTSSQACVVCEEG 307
Score = 42.3 bits (95), Expect = 0.010
Identities = 15/29 (51%), Positives = 19/29 (65%)
Query: 1018 ICLPCHYTCATCAGPHDSQCVSCLDDAEL 1046
+C PCH +CATC GP + C+SC A L
Sbjct: 345 VCAPCHASCATCQGPALTDCLSCPSHASL 373
>AL589653-1|CAI40809.1| 1560|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 1560
Score = 278 bits (682), Expect = 7e-74
Identities = 142/284 (50%), Positives = 179/284 (63%), Gaps = 11/284 (3%)
Query: 297 NSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSA 356
NSI+T+SISS E G PWY E+CSSTLA TYSSG + +++TTDL CT HTGTSA
Sbjct: 1 NSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSA 60
Query: 357 SAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGL 416
SAP+AAGI ALAL+AN LTWRD+QH++VRT+R L+ + +W+ N G VSH +G+GL
Sbjct: 61 SAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN-ANDWKTNAAGFKVSHLYGFGL 119
Query: 417 LDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAIALQLAVSSCPG-----VNYLE 471
+DA MV A+ W TVP Q C + R + I P SA+ S C VNYLE
Sbjct: 120 MDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNRHVNYLE 179
Query: 472 HVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLG 531
HV RI+++ RRGDL I LTSP+GT LLA R D S GF +W FM++H WGE G
Sbjct: 180 HVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAG 239
Query: 532 EWQLEV----TNEGRYMGRASLQEWSLTLYGTST-PAAKNDPIP 570
+W LEV + + L+EWSL LYGTS P + + P
Sbjct: 240 DWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFP 283
Score = 60.1 bits (139), Expect = 5e-08
Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
Query: 951 LYNGRCYSRCPDGTYANEISME-RSSRRRNLTIFSEGSLSKRQDGSL---KSSALEALDM 1006
LY+G C CP GTY + + E R + LT S G+ + Q G + + S +
Sbjct: 1096 LYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC 1155
Query: 1007 EPYANSTKDPLICLPCHYTCATCAGPHDSQCVSCLDDAELFNST 1050
P +D C PCH C C GP + QC +C ++ L N+T
Sbjct: 1156 SPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTT 1199
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/102 (24%), Positives = 40/102 (39%), Gaps = 2/102 (1%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKRQDGSLKSSALEAL 1004
CA G + ++ CY CP+ TY+ E+ + N + ++G
Sbjct: 729 CAMGYYRFDHHCYKTCPEKTYSEEVECKACDS--NCGSCDQNGCYWCEEGFFLLGGSCVR 786
Query: 1005 DMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSCLDDAEL 1046
P ++ C CH C TC GP +C SC + +L
Sbjct: 787 KCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQL 828
Score = 42.3 bits (95), Expect = 0.010
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 956 CYSRCPDGTYAN-EISMERSSRRRNLTIFSEGSLSKRQDG-SLKSSALEALDMEPYANST 1013
C + CPDG+Y + + ++ R T + ++ +DG SL+ S + +
Sbjct: 393 CVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNG 452
Query: 1014 KDPLICLPCHYTCATCAGPHDSQCVSCLD 1042
+D C PCH CATCAG C++C +
Sbjct: 453 QD---CQPCHRFCATCAGAGADGCINCTE 478
Score = 39.5 bits (88), Expect = 0.068
Identities = 16/38 (42%), Positives = 22/38 (57%)
Query: 938 CMDADRECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
C + L L+ GRCYS+CP+G+YA + ER S
Sbjct: 944 CKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCS 981
Score = 35.9 bits (79), Expect = 0.84
Identities = 11/26 (42%), Positives = 15/26 (57%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLDDA 1044
C+PCH C C+GP C CL+ +
Sbjct: 1068 CVPCHKDCLECSGPKADDCELCLESS 1093
Score = 35.5 bits (78), Expect = 1.1
Identities = 12/22 (54%), Positives = 13/22 (59%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSC 1040
C CH +C TC G H QC SC
Sbjct: 1217 CAHCHSSCRTCEGRHSRQCHSC 1238
Score = 35.1 bits (77), Expect = 1.5
Identities = 11/22 (50%), Positives = 13/22 (59%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSC 1040
C PCH+TC C G + C SC
Sbjct: 605 CHPCHHTCQRCQGSGPTHCTSC 626
Score = 34.3 bits (75), Expect = 2.6
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 6/100 (6%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKR---QDG-SLKSSA 1000
C KG +L C S CP GT+ + S + I S L K+ Q G L
Sbjct: 900 CPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHE 959
Query: 1001 LEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
P + +D IC C C TC G + + C SC
Sbjct: 960 GRCYSKCPEGSYAEDG-ICERCSSPCRTCEG-NATNCHSC 997
Score = 33.9 bits (74), Expect = 3.4
Identities = 25/104 (24%), Positives = 39/104 (37%), Gaps = 8/104 (7%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISME--RSSRRRNLTIFSEGSLSKRQDGSLKSSALE 1002
C +G + +GRC C Y + S +S ++ +++ + + S S L
Sbjct: 476 CTEGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLL 535
Query: 1003 ALDMEPYANSTKDPLI------CLPCHYTCATCAGPHDSQCVSC 1040
L M KD C C +CA C GP C +C
Sbjct: 536 DLGMCQMGAICKDGEYVDEHGHCQTCEASCAKCQGPTQEDCTTC 579
>AL391868-1|CAI40675.1| 1560|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 1560
Score = 278 bits (682), Expect = 7e-74
Identities = 142/284 (50%), Positives = 179/284 (63%), Gaps = 11/284 (3%)
Query: 297 NSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSA 356
NSI+T+SISS E G PWY E+CSSTLA TYSSG + +++TTDL CT HTGTSA
Sbjct: 1 NSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSA 60
Query: 357 SAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGL 416
SAP+AAGI ALAL+AN LTWRD+QH++VRT+R L+ + +W+ N G VSH +G+GL
Sbjct: 61 SAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN-ANDWKTNAAGFKVSHLYGFGL 119
Query: 417 LDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAIALQLAVSSCPG-----VNYLE 471
+DA MV A+ W TVP Q C + R + I P SA+ S C VNYLE
Sbjct: 120 MDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNRHVNYLE 179
Query: 472 HVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLG 531
HV RI+++ RRGDL I LTSP+GT LLA R D S GF +W FM++H WGE G
Sbjct: 180 HVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAG 239
Query: 532 EWQLEV----TNEGRYMGRASLQEWSLTLYGTST-PAAKNDPIP 570
+W LEV + + L+EWSL LYGTS P + + P
Sbjct: 240 DWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFP 283
Score = 60.1 bits (139), Expect = 5e-08
Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
Query: 951 LYNGRCYSRCPDGTYANEISME-RSSRRRNLTIFSEGSLSKRQDGSL---KSSALEALDM 1006
LY+G C CP GTY + + E R + LT S G+ + Q G + + S +
Sbjct: 1096 LYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC 1155
Query: 1007 EPYANSTKDPLICLPCHYTCATCAGPHDSQCVSCLDDAELFNST 1050
P +D C PCH C C GP + QC +C ++ L N+T
Sbjct: 1156 SPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTT 1199
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/102 (24%), Positives = 40/102 (39%), Gaps = 2/102 (1%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKRQDGSLKSSALEAL 1004
CA G + ++ CY CP+ TY+ E+ + N + ++G
Sbjct: 729 CAMGYYRFDHHCYKTCPEKTYSEEVECKACDS--NCGSCDQNGCYWCEEGFFLLGGSCVR 786
Query: 1005 DMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSCLDDAEL 1046
P ++ C CH C TC GP +C SC + +L
Sbjct: 787 KCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQL 828
Score = 42.3 bits (95), Expect = 0.010
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 956 CYSRCPDGTYAN-EISMERSSRRRNLTIFSEGSLSKRQDG-SLKSSALEALDMEPYANST 1013
C + CPDG+Y + + ++ R T + ++ +DG SL+ S + +
Sbjct: 393 CVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNG 452
Query: 1014 KDPLICLPCHYTCATCAGPHDSQCVSCLD 1042
+D C PCH CATCAG C++C +
Sbjct: 453 QD---CQPCHRFCATCAGAGADGCINCTE 478
Score = 39.5 bits (88), Expect = 0.068
Identities = 16/38 (42%), Positives = 22/38 (57%)
Query: 938 CMDADRECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
C + L L+ GRCYS+CP+G+YA + ER S
Sbjct: 944 CKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCS 981
Score = 35.9 bits (79), Expect = 0.84
Identities = 11/26 (42%), Positives = 15/26 (57%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLDDA 1044
C+PCH C C+GP C CL+ +
Sbjct: 1068 CVPCHKDCLECSGPKADDCELCLESS 1093
Score = 35.5 bits (78), Expect = 1.1
Identities = 12/22 (54%), Positives = 13/22 (59%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSC 1040
C CH +C TC G H QC SC
Sbjct: 1217 CAHCHSSCRTCEGRHSRQCHSC 1238
Score = 35.1 bits (77), Expect = 1.5
Identities = 11/22 (50%), Positives = 13/22 (59%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSC 1040
C PCH+TC C G + C SC
Sbjct: 605 CHPCHHTCQRCQGSGPTHCTSC 626
Score = 34.3 bits (75), Expect = 2.6
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 6/100 (6%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKR---QDG-SLKSSA 1000
C KG +L C S CP GT+ + S + I S L K+ Q G L
Sbjct: 900 CPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHE 959
Query: 1001 LEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
P + +D IC C C TC G + + C SC
Sbjct: 960 GRCYSKCPEGSYAEDG-ICERCSSPCRTCEG-NATNCHSC 997
Score = 33.9 bits (74), Expect = 3.4
Identities = 25/104 (24%), Positives = 39/104 (37%), Gaps = 8/104 (7%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISME--RSSRRRNLTIFSEGSLSKRQDGSLKSSALE 1002
C +G + +GRC C Y + S +S ++ +++ + + S S L
Sbjct: 476 CTEGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLL 535
Query: 1003 ALDMEPYANSTKDPLI------CLPCHYTCATCAGPHDSQCVSC 1040
L M KD C C +CA C GP C +C
Sbjct: 536 DLGMCQMGAICKDGEYVDEHGHCQTCEASCAKCQGPTQEDCTTC 579
>AL353607-3|CAI41234.1| 1560|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 1560
Score = 278 bits (682), Expect = 7e-74
Identities = 142/284 (50%), Positives = 179/284 (63%), Gaps = 11/284 (3%)
Query: 297 NSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSA 356
NSI+T+SISS E G PWY E+CSSTLA TYSSG + +++TTDL CT HTGTSA
Sbjct: 1 NSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSA 60
Query: 357 SAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGL 416
SAP+AAGI ALAL+AN LTWRD+QH++VRT+R L+ + +W+ N G VSH +G+GL
Sbjct: 61 SAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN-ANDWKTNAAGFKVSHLYGFGL 119
Query: 417 LDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAIALQLAVSSCPG-----VNYLE 471
+DA MV A+ W TVP Q C + R + I P SA+ S C VNYLE
Sbjct: 120 MDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNRHVNYLE 179
Query: 472 HVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLG 531
HV RI+++ RRGDL I LTSP+GT LLA R D S GF +W FM++H WGE G
Sbjct: 180 HVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAG 239
Query: 532 EWQLEV----TNEGRYMGRASLQEWSLTLYGTST-PAAKNDPIP 570
+W LEV + + L+EWSL LYGTS P + + P
Sbjct: 240 DWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFP 283
Score = 60.1 bits (139), Expect = 5e-08
Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
Query: 951 LYNGRCYSRCPDGTYANEISME-RSSRRRNLTIFSEGSLSKRQDGSL---KSSALEALDM 1006
LY+G C CP GTY + + E R + LT S G+ + Q G + + S +
Sbjct: 1096 LYDGLCLEECPAGTYYEKETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC 1155
Query: 1007 EPYANSTKDPLICLPCHYTCATCAGPHDSQCVSCLDDAELFNST 1050
P +D C PCH C C GP + QC +C ++ L N+T
Sbjct: 1156 SPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTT 1199
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/102 (24%), Positives = 40/102 (39%), Gaps = 2/102 (1%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKRQDGSLKSSALEAL 1004
CA G + ++ CY CP+ TY+ E+ + N + ++G
Sbjct: 729 CAMGYYRFDHHCYKTCPEKTYSEEVECKACDS--NCGSCDQNGCYWCEEGFFLLGGSCVR 786
Query: 1005 DMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSCLDDAEL 1046
P ++ C CH C TC GP +C SC + +L
Sbjct: 787 KCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQL 828
Score = 42.3 bits (95), Expect = 0.010
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 956 CYSRCPDGTYAN-EISMERSSRRRNLTIFSEGSLSKRQDG-SLKSSALEALDMEPYANST 1013
C + CPDG+Y + + ++ R T + ++ +DG SL+ S + +
Sbjct: 393 CVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNG 452
Query: 1014 KDPLICLPCHYTCATCAGPHDSQCVSCLD 1042
+D C PCH CATCAG C++C +
Sbjct: 453 QD---CQPCHRFCATCAGAGADGCINCTE 478
Score = 39.5 bits (88), Expect = 0.068
Identities = 16/38 (42%), Positives = 22/38 (57%)
Query: 938 CMDADRECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
C + L L+ GRCYS+CP+G+YA + ER S
Sbjct: 944 CKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCS 981
Score = 35.9 bits (79), Expect = 0.84
Identities = 11/26 (42%), Positives = 15/26 (57%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLDDA 1044
C+PCH C C+GP C CL+ +
Sbjct: 1068 CVPCHKDCLECSGPKADDCELCLESS 1093
Score = 35.5 bits (78), Expect = 1.1
Identities = 12/22 (54%), Positives = 13/22 (59%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSC 1040
C CH +C TC G H QC SC
Sbjct: 1217 CAHCHSSCRTCEGRHSRQCHSC 1238
Score = 35.1 bits (77), Expect = 1.5
Identities = 11/22 (50%), Positives = 13/22 (59%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSC 1040
C PCH+TC C G + C SC
Sbjct: 605 CHPCHHTCQRCQGSGPTHCTSC 626
Score = 34.3 bits (75), Expect = 2.6
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 6/100 (6%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKR---QDG-SLKSSA 1000
C KG +L C S CP GT+ + S + I S L K+ Q G L
Sbjct: 900 CPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHE 959
Query: 1001 LEALDMEPYANSTKDPLICLPCHYTCATCAGPHDSQCVSC 1040
P + +D IC C C TC G + + C SC
Sbjct: 960 GRCYSKCPEGSYAEDG-ICERCSSPCRTCEG-NATNCHSC 997
Score = 33.9 bits (74), Expect = 3.4
Identities = 25/104 (24%), Positives = 39/104 (37%), Gaps = 8/104 (7%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISME--RSSRRRNLTIFSEGSLSKRQDGSLKSSALE 1002
C +G + +GRC C Y + S +S ++ +++ + + S S L
Sbjct: 476 CTEGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLL 535
Query: 1003 ALDMEPYANSTKDPLI------CLPCHYTCATCAGPHDSQCVSC 1040
L M KD C C +CA C GP C +C
Sbjct: 536 DLGMCQMGAICKDGEYVDEHGHCQTCEASCAKCQGPTQEDCTTC 579
>X15723-1|CAA33745.1| 280|Homo sapiens furin protein.
Length = 280
Score = 231 bits (564), Expect = 1e-59
Identities = 105/185 (56%), Positives = 125/185 (67%)
Query: 83 LNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGGLDMNVIPAWREGITGRGVVVTILDDG 142
L ++ R D+ DPK+P WYL+ D+NV AW +G TG G+VV+ILDDG
Sbjct: 96 LEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDG 155
Query: 143 LETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCXXXX 202
+E +HPDL NYDP AS+DVN DPDPQPRY ++ NRHGTRCAGEVAA ANN +C
Sbjct: 156 IEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGV 215
Query: 203 XXXXXXXXXXMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFI 262
MLDG+VTD VEARSL LNP H+ IYSASWGP+DDGKTVDGP LA AF
Sbjct: 216 AYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFF 275
Query: 263 EGVTK 267
GV++
Sbjct: 276 RGVSQ 280
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/49 (53%), Positives = 33/49 (67%)
Query: 1 IFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRD 49
IF D+YHF HR +TKRSL+P H RL+ + +V+W EQQ R KRD
Sbjct: 60 IFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRD 108
>BC036354-1|AAH36354.1| 242|Homo sapiens PCSK4 protein protein.
Length = 242
Score = 74.5 bits (175), Expect = 2e-12
Identities = 32/65 (49%), Positives = 41/65 (63%)
Query: 496 GTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLGEWQLEVTNEGRYMGRASLQEWSLT 555
GT TL+A RP D S G+N+W FMS H W ENP G W L + N+G Y +L ++L
Sbjct: 2 GTRSTLVAIRPLDVSTEGYNNWVFMSTHFWDENPQGVWTLGLENKGYYFNTGTLYRYTLL 61
Query: 556 LYGTS 560
LYGT+
Sbjct: 62 LYGTA 66
>AF057710-1|AAD55137.1| 259|Homo sapiens lymphoma pro-protein
convertase protein.
Length = 259
Score = 71.3 bits (167), Expect = 2e-11
Identities = 34/89 (38%), Positives = 50/89 (56%), Gaps = 1/89 (1%)
Query: 472 HVQARISLSAARRGDLRITLTSPAGTNVTLLAPRPHDSSHSGFNSWPFMSVHMWGENPLG 531
HV +S++ RRG L + L P+G + APR DS +GFN W F +V WGE G
Sbjct: 1 HVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARG 60
Query: 532 EWQLEVTNEGRYMGRAS-LQEWSLTLYGT 559
++L + + G + L++W LTLYG+
Sbjct: 61 TYRLVIRDVGDESFQVGILRQWQLTLYGS 89
>BC131820-1|AAI31821.1| 1976|Homo sapiens FRAS1 protein protein.
Length = 1976
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/98 (27%), Positives = 34/98 (34%), Gaps = 4/98 (4%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKRQDGSLKSSALEAL 1004
C + L++G+C S CP G YA+ R N G AL
Sbjct: 578 CTEKTVLHDGKCMSECPGGYYADATG--RCKVCHNSCASCSGPTPSHCTACSPPKALRQG 635
Query: 1005 DMEPYANST--KDPLICLPCHYTCATCAGPHDSQCVSC 1040
P D +C CH +C C GP S C C
Sbjct: 636 HCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGC 673
Score = 38.3 bits (85), Expect = 0.16
Identities = 14/30 (46%), Positives = 16/30 (53%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLDDAELFN 1048
C CH TC C GP +S C+SC L N
Sbjct: 758 CTECHPTCRQCHGPLESDCISCYPHISLTN 787
Score = 34.7 bits (76), Expect = 1.9
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLD 1042
C CH +CA C GP + C++C D
Sbjct: 510 CAVCHESCAGCWGPTEKHCLACRD 533
Score = 33.9 bits (74), Expect = 3.4
Identities = 9/24 (37%), Positives = 16/24 (66%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLD 1042
C C ++C+ C+GP + C+ C+D
Sbjct: 955 CKECDWSCSACSGPLKTDCLQCMD 978
>BC064487-1|AAH64487.1| 651|Homo sapiens FRAS1 protein protein.
Length = 651
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/98 (27%), Positives = 34/98 (34%), Gaps = 4/98 (4%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKRQDGSLKSSALEAL 1004
C + L++G+C S CP G YA+ R N G AL
Sbjct: 420 CTEKTVLHDGKCMSECPGGYYADATG--RCKVCHNSCASCSGPTPSHCTACSPPKALRQG 477
Query: 1005 DMEPYANST--KDPLICLPCHYTCATCAGPHDSQCVSC 1040
P D +C CH +C C GP S C C
Sbjct: 478 HCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGC 515
Score = 38.3 bits (85), Expect = 0.16
Identities = 14/30 (46%), Positives = 16/30 (53%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLDDAELFN 1048
C CH TC C GP +S C+SC L N
Sbjct: 600 CTECHPTCRQCHGPLESDCISCYPHISLTN 629
Score = 34.7 bits (76), Expect = 1.9
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLD 1042
C CH +CA C GP + C++C D
Sbjct: 352 CAVCHESCAGCWGPTEKHCLACRD 375
>BC052281-1|AAH52281.1| 651|Homo sapiens FRAS1 protein protein.
Length = 651
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/98 (27%), Positives = 34/98 (34%), Gaps = 4/98 (4%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKRQDGSLKSSALEAL 1004
C + L++G+C S CP G YA+ R N G AL
Sbjct: 420 CTEKTVLHDGKCMSECPGGYYADATG--RCKVCHNSCASCSGPTPSHCTACSPPKALRQG 477
Query: 1005 DMEPYANST--KDPLICLPCHYTCATCAGPHDSQCVSC 1040
P D +C CH +C C GP S C C
Sbjct: 478 HCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGC 515
Score = 38.3 bits (85), Expect = 0.16
Identities = 14/30 (46%), Positives = 16/30 (53%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLDDAELFN 1048
C CH TC C GP +S C+SC L N
Sbjct: 600 CTECHPTCRQCHGPLESDCISCYPHISLTN 629
Score = 34.7 bits (76), Expect = 1.9
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLD 1042
C CH +CA C GP + C++C D
Sbjct: 352 CAVCHESCAGCWGPTEKHCLACRD 375
>AK027833-1|BAB55399.1| 441|Homo sapiens protein ( Homo sapiens cDNA
FLJ14927 fis, clone PLACE1009094, weakly similar to
FURIN-LIKE PROTEASE 2 PRECURSOR (EC 3.4.21.75). ).
Length = 441
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/98 (27%), Positives = 34/98 (34%), Gaps = 4/98 (4%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKRQDGSLKSSALEAL 1004
C + L++G+C S CP G YA+ R N G AL
Sbjct: 282 CTEKTVLHDGKCMSECPGGYYADATG--RCKVCHNSCASCSGPTPSHCTACSPPKALRQG 339
Query: 1005 DMEPYANST--KDPLICLPCHYTCATCAGPHDSQCVSC 1040
P D +C CH +C C GP S C C
Sbjct: 340 HCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGC 377
Score = 34.7 bits (76), Expect = 1.9
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLD 1042
C CH +CA C GP + C++C D
Sbjct: 214 CAVCHESCAGCWGPTEKHCLACRD 237
>AJ512501-1|CAD54734.1| 4007|Homo sapiens extracellular matrix protein
protein.
Length = 4007
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/98 (27%), Positives = 34/98 (34%), Gaps = 4/98 (4%)
Query: 945 CAKGLHLYNGRCYSRCPDGTYANEISMERSSRRRNLTIFSEGSLSKRQDGSLKSSALEAL 1004
C + L++G+C S CP G YA+ R N G AL
Sbjct: 578 CTEKTVLHDGKCMSECPGGYYADATG--RCKVCHNSCASCSGPTPSHCTACSPPKALRQG 635
Query: 1005 DMEPYANST--KDPLICLPCHYTCATCAGPHDSQCVSC 1040
P D +C CH +C C GP S C C
Sbjct: 636 HCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGC 673
Score = 38.3 bits (85), Expect = 0.16
Identities = 14/30 (46%), Positives = 16/30 (53%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLDDAELFN 1048
C CH TC C GP +S C+SC L N
Sbjct: 758 CTECHPTCRQCHGPLESDCISCYPHISLTN 787
Score = 34.7 bits (76), Expect = 1.9
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLD 1042
C CH +CA C GP + C++C D
Sbjct: 510 CAVCHESCAGCWGPTEKHCLACRD 533
Score = 33.9 bits (74), Expect = 3.4
Identities = 9/24 (37%), Positives = 16/24 (66%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLD 1042
C C ++C+ C+GP + C+ C+D
Sbjct: 955 CKECDWSCSACSGPLKTDCLQCMD 978
>DQ318235-1|ABC54570.1| 263|Homo sapiens R-spondin 1 protein.
Length = 263
Score = 40.3 bits (90), Expect = 0.039
Identities = 16/32 (50%), Positives = 23/32 (71%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
+C +GL+L+ GRCY CP+G+ A +ME SS
Sbjct: 113 KCKEGLYLHKGRCYPACPEGSSAANGTMECSS 144
>DQ165085-1|ABA54598.1| 200|Homo sapiens R-spondin isoform 2
protein.
Length = 200
Score = 40.3 bits (90), Expect = 0.039
Identities = 16/32 (50%), Positives = 23/32 (71%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
+C +GL+L+ GRCY CP+G+ A +ME SS
Sbjct: 113 KCKEGLYLHKGRCYPACPEGSSAANGTMECSS 144
>DQ165084-1|ABA54597.1| 263|Homo sapiens R-spondin isoform 1
protein.
Length = 263
Score = 40.3 bits (90), Expect = 0.039
Identities = 16/32 (50%), Positives = 23/32 (71%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
+C +GL+L+ GRCY CP+G+ A +ME SS
Sbjct: 113 KCKEGLYLHKGRCYPACPEGSSAANGTMECSS 144
>BC114966-1|AAI14967.1| 263|Homo sapiens R-spondin homolog (Xenopus
laevis) protein.
Length = 263
Score = 40.3 bits (90), Expect = 0.039
Identities = 16/32 (50%), Positives = 23/32 (71%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
+C +GL+L+ GRCY CP+G+ A +ME SS
Sbjct: 113 KCKEGLYLHKGRCYPACPEGSSAANGTMECSS 144
>AL513220-4|CAI15785.1| 236|Homo sapiens R-spondin homolog (Xenopus
laevis) protein.
Length = 236
Score = 40.3 bits (90), Expect = 0.039
Identities = 16/32 (50%), Positives = 23/32 (71%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
+C +GL+L+ GRCY CP+G+ A +ME SS
Sbjct: 86 KCKEGLYLHKGRCYPACPEGSSAANGTMECSS 117
>AL513220-3|CAM12883.1| 263|Homo sapiens R-spondin homolog (Xenopus
laevis) protein.
Length = 263
Score = 40.3 bits (90), Expect = 0.039
Identities = 16/32 (50%), Positives = 23/32 (71%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
+C +GL+L+ GRCY CP+G+ A +ME SS
Sbjct: 113 KCKEGLYLHKGRCYPACPEGSSAANGTMECSS 144
>AL513220-2|CAM12882.1| 200|Homo sapiens R-spondin homolog (Xenopus
laevis) protein.
Length = 200
Score = 40.3 bits (90), Expect = 0.039
Identities = 16/32 (50%), Positives = 23/32 (71%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
+C +GL+L+ GRCY CP+G+ A +ME SS
Sbjct: 113 KCKEGLYLHKGRCYPACPEGSSAANGTMECSS 144
>AK098225-1|BAC05263.1| 236|Homo sapiens protein ( Homo sapiens
cDNA FLJ40906 fis, clone UTERU2004698, highly similar to
Mus musculus mRNA for thrombospondin type 1 domain. ).
Length = 236
Score = 40.3 bits (90), Expect = 0.039
Identities = 16/32 (50%), Positives = 23/32 (71%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISMERSS 975
+C +GL+L+ GRCY CP+G+ A +ME SS
Sbjct: 86 KCKEGLYLHKGRCYPACPEGSSAANGTMECSS 117
>S65442-1|AAB28140.1| 69|Homo sapiens furin protein.
Length = 69
Score = 39.1 bits (87), Expect = 0.090
Identities = 16/28 (57%), Positives = 21/28 (75%), Gaps = 1/28 (3%)
Query: 389 RPERLSLSGEWRINGVGRNVSHSFGYGL 416
+P L+ + +W NGVGR VSHS+GYGL
Sbjct: 1 KPAHLN-ANDWATNGVGRKVSHSYGYGL 27
>BC036554-1|AAH36554.1| 179|Homo sapiens RSPO2 protein protein.
Length = 179
Score = 36.7 bits (81), Expect = 0.48
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 937 SCMDAD--RECAKGLHLYNGRCYSRCPDGTYANEISME 972
SC D +C G +L+ GRC+ CPDG E +ME
Sbjct: 40 SCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETME 77
>BC027938-1|AAH27938.1| 176|Homo sapiens RSPO2 protein protein.
Length = 176
Score = 36.7 bits (81), Expect = 0.48
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 937 SCMDAD--RECAKGLHLYNGRCYSRCPDGTYANEISME 972
SC D +C G +L+ GRC+ CPDG E +ME
Sbjct: 36 SCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETME 73
>AY358166-1|AAQ88533.1| 243|Homo sapiens QFRL9384 protein.
Length = 243
Score = 36.7 bits (81), Expect = 0.48
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 937 SCMDAD--RECAKGLHLYNGRCYSRCPDGTYANEISME 972
SC D +C G +L+ GRC+ CPDG E +ME
Sbjct: 103 SCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETME 140
>AL353607-4|CAI41235.1| 101|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 101
Score = 36.3 bits (80), Expect = 0.63
Identities = 12/24 (50%), Positives = 15/24 (62%)
Query: 1019 CLPCHYTCATCAGPHDSQCVSCLD 1042
C PCH CATCAG C++C +
Sbjct: 1 CQPCHRFCATCAGAGADGCINCTE 24
>BC008720-1|AAH08720.1| 422|Homo sapiens cysteine-rich with EGF-like
domains 1 protein.
Length = 422
Score = 35.1 bits (77), Expect = 1.5
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 1017 LICLPCHYTCATCAGPHDSQCVSC 1040
L+C C CA C+GP +S C+ C
Sbjct: 209 LVCSACFGPCARCSGPEESNCLQC 232
>AY358363-1|AAQ88729.1| 420|Homo sapiens CRELD1 protein.
Length = 420
Score = 35.1 bits (77), Expect = 1.5
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 1017 LICLPCHYTCATCAGPHDSQCVSC 1040
L+C C CA C+GP +S C+ C
Sbjct: 209 LVCSACFGPCARCSGPEESNCLQC 232
>AF452623-1|AAM75206.1| 420|Homo sapiens cysteine-rich with EGF-like
domains 1 protein.
Length = 420
Score = 35.1 bits (77), Expect = 1.5
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 1017 LICLPCHYTCATCAGPHDSQCVSC 1040
L+C C CA C+GP +S C+ C
Sbjct: 209 LVCSACFGPCARCSGPEESNCLQC 232
>AB209088-1|BAD92325.1| 514|Homo sapiens synapsin II isoform IIb
variant protein.
Length = 514
Score = 34.7 bits (76), Expect = 1.9
Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 3/110 (2%)
Query: 401 INGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAIALQLA 460
+N + R +S S L M L + PP A+P P R PP SA A Q A
Sbjct: 50 MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPTASPGPERRPPPASAPAPQPA 109
Query: 461 VSSCPGVNYLEHVQARISLSAARRGDLRITLTSPAG---TNVTLLAPRPH 507
+ G ++ + + +AA G + +PA V L+ PH
Sbjct: 110 PTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVDEPH 159
>BC022367-1|AAH22367.1| 272|Homo sapiens R-spondin 3 homolog
(Xenopus laevis) protein.
Length = 272
Score = 34.3 bits (75), Expect = 2.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISME 972
+C G +L+ G+C CP+G AN +ME
Sbjct: 113 KCKSGFYLHLGKCLDNCPEGLEANNHTME 141
>AL590733-2|CAH71125.1| 292|Homo sapiens R-spondin 3 homolog
(Xenopus laevis) protein.
Length = 292
Score = 34.3 bits (75), Expect = 2.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISME 972
+C G +L+ G+C CP+G AN +ME
Sbjct: 113 KCKSGFYLHLGKCLDNCPEGLEANNHTME 141
>AL590733-1|CAH71124.1| 272|Homo sapiens R-spondin 3 homolog
(Xenopus laevis) protein.
Length = 272
Score = 34.3 bits (75), Expect = 2.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISME 972
+C G +L+ G+C CP+G AN +ME
Sbjct: 113 KCKSGFYLHLGKCLDNCPEGLEANNHTME 141
>AL031776-2|CAI20142.1| 292|Homo sapiens R-spondin 3 homolog
(Xenopus laevis) protein.
Length = 292
Score = 34.3 bits (75), Expect = 2.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISME 972
+C G +L+ G+C CP+G AN +ME
Sbjct: 113 KCKSGFYLHLGKCLDNCPEGLEANNHTME 141
>AL031776-1|CAI20141.1| 272|Homo sapiens R-spondin 3 homolog
(Xenopus laevis) protein.
Length = 272
Score = 34.3 bits (75), Expect = 2.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISME 972
+C G +L+ G+C CP+G AN +ME
Sbjct: 113 KCKSGFYLHLGKCLDNCPEGLEANNHTME 141
>AK027346-1|BAB55051.1| 292|Homo sapiens protein ( Homo sapiens
cDNA FLJ14440 fis, clone HEMBB1000915, weakly similar to
SUBTILISIN-LIKE PROTEASE PACE4 PRECURSOR (EC 3.4.21.-).
).
Length = 292
Score = 34.3 bits (75), Expect = 2.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISME 972
+C G +L+ G+C CP+G AN +ME
Sbjct: 113 KCKSGFYLHLGKCLDNCPEGLEANNHTME 141
>AF251057-1|AAK34947.1| 272|Homo sapiens thrombospondin protein.
Length = 272
Score = 34.3 bits (75), Expect = 2.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 944 ECAKGLHLYNGRCYSRCPDGTYANEISME 972
+C G +L+ G+C CP+G AN +ME
Sbjct: 113 KCKSGFYLHLGKCLDNCPEGLEANNHTME 141
>DQ355152-1|ABC75877.1| 172|Homo sapiens R-spondin family member 4
variant protein.
Length = 172
Score = 33.5 bits (73), Expect = 4.5
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 937 SCMDADR--ECAKGLHLYNGRCYSRCPDGTYANEISMERSSR 976
SC D C + +LY G+C CP GT A++ + E R
Sbjct: 97 SCFSQDFCIRCKRQFYLYKGKCLPTCPPGTLAHQNTRECQER 138
>AL050325-3|CAM28322.1| 172|Homo sapiens R-spondin family, member 4
protein.
Length = 172
Score = 33.5 bits (73), Expect = 4.5
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 937 SCMDADR--ECAKGLHLYNGRCYSRCPDGTYANEISMERSSR 976
SC D C + +LY G+C CP GT A++ + E R
Sbjct: 97 SCFSQDFCIRCKRQFYLYKGKCLPTCPPGTLAHQNTRECQER 138
>X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2
mRNA. ).
Length = 1255
Score = 33.1 bits (72), Expect = 5.9
Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 6/28 (21%)
Query: 1019 CLPCHYTC------ATCAGPHDSQCVSC 1040
CLPCH C TC GP QCV+C
Sbjct: 560 CLPCHPECQPQNGSVTCFGPEADQCVAC 587
>M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine
kinase-type receptor (HER2) mRNA, complete cds. ).
Length = 1255
Score = 33.1 bits (72), Expect = 5.9
Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 6/28 (21%)
Query: 1019 CLPCHYTC------ATCAGPHDSQCVSC 1040
CLPCH C TC GP QCV+C
Sbjct: 560 CLPCHPECQPQNGSVTCFGPEADQCVAC 587
>AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 2, neuro/glioblastoma d
protein.
Length = 1255
Score = 33.1 bits (72), Expect = 5.9
Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 6/28 (21%)
Query: 1019 CLPCHYTC------ATCAGPHDSQCVSC 1040
CLPCH C TC GP QCV+C
Sbjct: 560 CLPCHPECQPQNGSVTCFGPEADQCVAC 587
>AK131568-1|BAD18701.1| 435|Homo sapiens protein ( Homo sapiens cDNA
FLJ16821 fis, clone TRACH3021066, highly similar to
Receptor protein-tyrosine kinase ERBB-2 precursor (EC
2.7.1.112). ).
Length = 435
Score = 33.1 bits (72), Expect = 5.9
Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 6/28 (21%)
Query: 1019 CLPCHYTC------ATCAGPHDSQCVSC 1040
CLPCH C TC GP QCV+C
Sbjct: 110 CLPCHPECQPQNGSVTCFGPEADQCVAC 137
>AB231710-1|BAE46876.1| 82|Homo sapiens hypothetical protein
protein.
Length = 82
Score = 33.1 bits (72), Expect = 5.9
Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 519 FMSVHMWGENPLGEWQLEVTNEGRYMGRAS-LQEWSLTLYGT 559
F +V WGE G ++L + + G + L++W LTLYG+
Sbjct: 1 FSTVRCWGERARGTYRLVIRDVGDESFQVGILRQWQLTLYGS 42
>X60299-1|CAA42841.1| 680|Homo sapiens KALIG-1 protein.
Length = 680
Score = 32.7 bits (71), Expect = 7.8
Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Query: 300 WTLSISSATERGDVPWYSEKCSS--TLAATYSSGAINENQVVTTDLHHSC 347
W + R V W+ E C+ T + SSG +EN ++ DL SC
Sbjct: 447 WKKTEDPTVNRYHVRWFPEACAHNRTTGSEASSGMTHENYIILQDLSFSC 496
>S60085-1|AAB20108.1| 679|Homo sapiens ADMLX protein.
Length = 679
Score = 32.7 bits (71), Expect = 7.8
Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Query: 300 WTLSISSATERGDVPWYSEKCSS--TLAATYSSGAINENQVVTTDLHHSC 347
W + R V W+ E C+ T + SSG +EN ++ DL SC
Sbjct: 446 WKKTEDPTVNRYHVRWFPEACAHNRTTGSEASSGMTHENYIILQDLSFSC 495
>M97252-1|AAA59202.1| 680|Homo sapiens KAL protein.
Length = 680
Score = 32.7 bits (71), Expect = 7.8
Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Query: 300 WTLSISSATERGDVPWYSEKCSS--TLAATYSSGAINENQVVTTDLHHSC 347
W + R V W+ E C+ T + SSG +EN ++ DL SC
Sbjct: 447 WKKTEDPTVNRYHVRWFPEACAHNRTTGSEASSGMTHENYIILQDLSFSC 496
>AL050325-2|CAB65783.4| 234|Homo sapiens R-spondin family, member 4
protein.
Length = 234
Score = 32.7 bits (71), Expect = 7.8
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Query: 937 SCMDADR--ECAKGLHLYNGRCYSRCPDGTYANEISME 972
SC D C + +LY G+C CP GT A++ + E
Sbjct: 97 SCFSQDFCIRCKRQFYLYKGKCLPTCPPGTLAHQNTRE 134
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.133 0.412
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 170,580,338
Number of Sequences: 224733
Number of extensions: 7243773
Number of successful extensions: 18516
Number of sequences better than 10.0: 96
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 17848
Number of HSP's gapped (non-prelim): 396
length of query: 1152
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1054
effective length of database: 51,211,004
effective search space: 53976398216
effective search space used: 53976398216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 71 (32.7 bits)
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