Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001510-TA|BGIBMGA001510-PA|IPR001412|Aminoacyl-tRNA
synthetase, class I, IPR005113|uDENN, IPR001194|DENN, IPR005112|dDENN,
IPR002885|Pentatricopeptide repeat
(1604 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC041706-1|AAH41706.1| 1863|Homo sapiens DENN/MADD domain contai... 424 e-117
BC028057-1|AAH28057.1| 933|Homo sapiens Unknown (protein for IM... 424 e-117
AK091368-1|BAC03648.1| 928|Homo sapiens protein ( Homo sapiens ... 424 e-117
AF534403-1|AAQ10514.1| 1865|Homo sapiens c-MYC promoter-binding ... 424 e-117
AL832602-1|CAD89960.1| 1831|Homo sapiens hypothetical protein pr... 424 e-117
AL391834-11|CAM21148.1| 1673|Homo sapiens DENN/MADD domain conta... 414 e-114
AL161909-3|CAH70581.2| 1673|Homo sapiens DENN/MADD domain contai... 414 e-114
AK125842-1|BAC86313.1| 1557|Homo sapiens protein ( Homo sapiens ... 413 e-114
AL358472-2|CAI14016.1| 1384|Homo sapiens DENN/MADD domain contai... 368 e-100
AB007945-1|BAA32321.3| 1626|Homo sapiens KIAA0476 protein protein. 368 e-100
AL391834-1|CAM21138.1| 1146|Homo sapiens DENN/MADD domain contai... 83 8e-15
AL391834-3|CAM21140.1| 670|Homo sapiens DENN/MADD domain contai... 80 6e-14
AL391834-2|CAM21139.1| 791|Homo sapiens DENN/MADD domain contai... 80 6e-14
AK025705-1|BAB15221.1| 791|Homo sapiens protein ( Homo sapiens ... 80 6e-14
AK002020-1|BAA92039.1| 324|Homo sapiens protein ( Homo sapiens ... 80 6e-14
AK001046-1|BAA91478.1| 452|Homo sapiens protein ( Homo sapiens ... 80 6e-14
AL391834-4|CAM21141.1| 258|Homo sapiens DENN/MADD domain contai... 80 7e-14
AK000693-1|BAA91324.1| 452|Homo sapiens protein ( Homo sapiens ... 80 7e-14
AK000627-1|BAA91294.1| 258|Homo sapiens protein ( Homo sapiens ... 80 7e-14
BC101466-1|AAI01467.1| 1849|Homo sapiens SET binding factor 2 pr... 79 2e-13
AY234241-1|AAO62733.1| 1849|Homo sapiens SET binding factor 2 pr... 79 2e-13
AB051553-1|BAB21857.1| 1123|Homo sapiens KIAA1766 protein protein. 79 2e-13
AB020677-1|BAA74893.2| 1019|Homo sapiens KIAA0870 protein protein. 69 1e-10
BC063877-1|AAH63877.1| 426|Homo sapiens DENND1B protein protein. 67 4e-10
AL365258-6|CAI14213.1| 426|Homo sapiens DENN/MADD domain contai... 67 4e-10
AL365258-5|CAI14214.1| 406|Homo sapiens DENN/MADD domain contai... 67 4e-10
AL139136-7|CAI15315.1| 406|Homo sapiens DENN/MADD domain contai... 67 4e-10
AL139136-6|CAI15314.1| 426|Homo sapiens DENN/MADD domain contai... 67 4e-10
BC087612-1|AAH87612.1| 1893|Homo sapiens SBF1 protein protein. 65 2e-09
BC022561-1|AAH22561.1| 396|Homo sapiens DENN/MADD domain contai... 65 2e-09
AL096767-2|CAI42962.1| 1867|Homo sapiens SET binding factor 1 pr... 65 2e-09
AB209682-1|BAD92919.1| 858|Homo sapiens SET binding factor 1 is... 65 2e-09
U15780-1|AAC50926.1| 717|Homo sapiens p82 protein. 64 5e-09
U15779-1|AAB97097.1| 609|Homo sapiens p70 protein. 64 5e-09
U15131-1|AAC50925.1| 1137|Homo sapiens p126 protein. 64 5e-09
S45936-1|AAB23647.1| 645|Homo sapiens HTS1 protein. 64 5e-09
BC036655-1|AAH36655.1| 1137|Homo sapiens suppression of tumorige... 64 5e-09
AJ400879-1|CAC35387.1| 1137|Homo sapiens suppression of tumorige... 64 5e-09
BC071596-1|AAH71596.1| 1287|Homo sapiens RAB6 interacting protei... 63 7e-09
AB029014-1|BAA83043.1| 1359|Homo sapiens KIAA1091 protein protein. 63 7e-09
BC068580-1|AAH68580.1| 738|Homo sapiens MGC24039 protein protein. 62 1e-08
BC020855-1|AAH20855.1| 507|Homo sapiens MGC24039 protein protein. 62 1e-08
AK125323-1|BAC86129.1| 1309|Homo sapiens protein ( Homo sapiens ... 62 1e-08
AL831839-1|CAD38548.1| 190|Homo sapiens hypothetical protein pr... 62 2e-08
AL133382-2|CAM27633.1| 928|Homo sapiens DENN/MADD domain contai... 60 6e-08
AL133382-1|CAI19301.1| 871|Homo sapiens DENN/MADD domain contai... 60 6e-08
U77352-1|AAB57735.1| 1588|Homo sapiens MAP kinase-activating dea... 60 8e-08
U44953-1|AAD12154.1| 1587|Homo sapiens DENN protein. 60 8e-08
BC040484-1|AAH40484.1| 1544|Homo sapiens MADD protein protein. 60 8e-08
AF440434-1|AAL35261.1| 1479|Homo sapiens insulinoma-glucagonoma ... 60 8e-08
AF440103-1|AAL40268.1| 1545|Homo sapiens insulinoma-glucagonoma ... 60 8e-08
AF440102-1|AAL40267.1| 1565|Homo sapiens insulinoma-glucagonoma ... 60 8e-08
AF440101-1|AAL40266.1| 1608|Homo sapiens insulinoma-glucagonoma ... 60 8e-08
AF440100-1|AAL40265.1| 1647|Homo sapiens insulinoma-glucagonoma ... 60 8e-08
AB002356-1|BAA20814.2| 1584|Homo sapiens KIAA0358 protein. 60 8e-08
BC132875-1|AAI32876.1| 1009|Homo sapiens DENN/MADD domain contai... 59 1e-07
BC049193-1|AAH49193.1| 638|Homo sapiens DENND2A protein protein. 59 1e-07
AB033103-1|BAA86591.2| 1039|Homo sapiens KIAA1277 protein protein. 57 4e-07
BC004557-1|AAH04557.1| 471|Homo sapiens DENN/MADD domain contai... 57 6e-07
AL355816-4|CAI19369.1| 468|Homo sapiens DENN/MADD domain contai... 57 6e-07
AL355816-3|CAI19368.1| 471|Homo sapiens DENN/MADD domain contai... 57 6e-07
U93181-1|AAC39675.1| 1697|Homo sapiens nuclear dual-specificity ... 56 8e-07
AK026110-1|BAB15363.1| 468|Homo sapiens protein ( Homo sapiens ... 55 2e-06
BC039703-1|AAH39703.1| 559|Homo sapiens DENN/MADD domain contai... 55 2e-06
BC028061-1|AAH28061.1| 505|Homo sapiens DENND1A protein protein. 55 2e-06
BC009616-1|AAH09616.1| 626|Homo sapiens DENND1A protein protein. 55 2e-06
AL445489-5|CAI39794.1| 466|Homo sapiens DENN/MADD domain contai... 55 2e-06
AL445489-2|CAI39792.1| 559|Homo sapiens DENN/MADD domain contai... 55 2e-06
AL445489-1|CAI39791.1| 1009|Homo sapiens DENN/MADD domain contai... 55 2e-06
AL390774-4|CAH73640.1| 466|Homo sapiens DENN/MADD domain contai... 55 2e-06
AL390774-2|CAH73638.1| 559|Homo sapiens DENN/MADD domain contai... 55 2e-06
AL390774-1|CAH73637.1| 1009|Homo sapiens DENN/MADD domain contai... 55 2e-06
AL161790-3|CAI15707.1| 466|Homo sapiens DENN/MADD domain contai... 55 2e-06
AL161790-2|CAI15706.1| 559|Homo sapiens DENN/MADD domain contai... 55 2e-06
AL161790-1|CAI15705.1| 1009|Homo sapiens DENN/MADD domain contai... 55 2e-06
AK074151-1|BAB84977.1| 896|Homo sapiens FLJ00224 protein protein. 55 2e-06
AK024782-1|BAB15002.1| 559|Homo sapiens protein ( Homo sapiens ... 55 2e-06
AB046828-1|BAB13434.2| 872|Homo sapiens KIAA1608 protein protein. 55 2e-06
BC133023-1|AAI33024.1| 1146|Homo sapiens DENND3 protein protein. 54 4e-06
BC033437-1|AAH33437.1| 801|Homo sapiens DENN/MADD domain contai... 52 2e-05
AK026410-1|BAB15475.1| 793|Homo sapiens protein ( Homo sapiens ... 52 2e-05
X63417-1|CAA45013.1| 191|Homo sapiens IRLB protein. 51 3e-05
AL450998-10|CAH70858.1| 3664|Homo sapiens SMART/HDAC1 associated... 34 3.6
AL096858-1|CAB51072.1| 3261|Homo sapiens hypothetical protein pr... 34 3.6
AL034555-4|CAI19526.1| 3664|Homo sapiens SMART/HDAC1 associated ... 34 3.6
AF356524-1|AAK52750.1| 3664|Homo sapiens nuclear receptor transc... 34 3.6
AB023146-1|BAA76773.1| 1663|Homo sapiens KIAA0929 protein protein. 34 3.6
BC009354-1|AAH09354.2| 948|Homo sapiens RAB6IP1 protein protein. 34 4.8
BC063894-1|AAH63894.1| 816|Homo sapiens DENND2C protein protein. 33 6.3
>BC041706-1|AAH41706.1| 1863|Homo sapiens DENN/MADD domain
containing 4A protein.
Length = 1863
Score = 424 bits (1045), Expect = e-117
Identities = 218/508 (42%), Positives = 313/508 (61%), Gaps = 23/508 (4%)
Query: 296 LLSPSNPSDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRP 355
+L +P D +I+++ PL SG F A+TE KILIHSLRP
Sbjct: 366 ILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRP 425
Query: 356 DTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVT 415
LT+V+EA+ S++FPF W CPY+PLCPL LA+VL AP P+++G+DSR+FDLY+PPPDV+
Sbjct: 426 SVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVS 485
Query: 416 CVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNGE 475
CVD+DTN I+ + N++ K+LPK+ K L TL L+ + R R +G
Sbjct: 486 CVDVDTNTISQI-GDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKL-----QQRPRDDGL 539
Query: 476 ATTSL-DRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDPDALF 534
++ D DF K+ ++L+IQEAFL FMA L+GYRSYL PIT+AP+ TD +LF
Sbjct: 540 MDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLF 599
Query: 535 QMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECIEKI---ASGE 591
+ FLRSR+++ Q+F+ +M +TQMF RFIEE SFV D D L FFD+C++K+ SGE
Sbjct: 600 ALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGE 659
Query: 592 ERLLGMDTTNASERTVFLLPPDPP------DPQKTYTYEKFSLDLNLIXXXXXXXXXXXX 645
RL+ +D + SE TVF+ PP+ P +P Y+Y F + N +
Sbjct: 660 VRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNNL-----FERPEGF 714
Query: 646 XXXXXXXXXXXXXXXXXXXPMAKRTKHEVAAAQRLARKASRSPEAWAKCLLGACYSLYFL 705
PM +RTK E+ +A ++A++ S P+ W++CLL CY L+F+
Sbjct: 715 LQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFI 774
Query: 706 TLPSRLMLNRGKEHATLRTAYELLERAAKLKV-PCDEVCYRVMMQLCGIHSFPVMAVQLL 764
LP+ + + K A L+TAY++L++ K+ P DEVCYR++MQLCG + PV+AV++L
Sbjct: 775 CLPAYVKVCHSKVRA-LKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVL 833
Query: 765 FLMKRAGLQPNALTYGCYNRWVLEANWP 792
F M++AG+ PNA+TYG YN+ VLE+ WP
Sbjct: 834 FEMQKAGIDPNAITYGYYNKAVLESTWP 861
Score = 285 bits (700), Expect = 7e-76
Identities = 138/284 (48%), Positives = 182/284 (64%), Gaps = 5/284 (1%)
Query: 16 VVFPTLGETVPDGYELVETTPTGLPADLNHGSMRSPECFLYLRRGRERPPLVDIGVMYDG 75
V+ +LGE VP Y ++ TPTGL ADLN+GS+ P+ +L RRGR++PPL D+GV+YD
Sbjct: 50 VIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDW 109
Query: 76 KERLMADAEMVLESSGGRVANVNNSAA--KTFITYRRAHPGAPCNALXXXXXXXXXXSKG 133
KERL E++ + GR AN++ S + + +ITYRRA N L SKG
Sbjct: 110 KERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKG 169
Query: 134 ECPPHAFCMIAKNLNKGLMGSDVFLCYKKSMNRPPLISYKPDVLFRYPVTDRRSLAFPPS 193
E PPH FC + KNLN + GS V+LCYKKS+ + +SYK ++ RYP D S + P S
Sbjct: 170 ESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYESFSLPES 229
Query: 194 VPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTETQ 253
VPLFCLPMGAT+E WP+N+ P PVFSTFVLT A A EKVYG+A+ FYE Y TE Q
Sbjct: 230 VPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASA-EKVYGAAIQFYEPYSEENPTEKQ 288
Query: 254 MELLGWRA--NVSQNTHSVHVVKSVCLLSRWPFSDTFERWLLYI 295
LLG + S ++ ++H K +CLLS WPF D F ++L ++
Sbjct: 289 RLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFL 332
Score = 79.0 bits (186), Expect = 1e-13
Identities = 32/62 (51%), Positives = 47/62 (75%)
Query: 1368 ETLTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPD 1427
+ +TVPYL+PLV+ KE ES+L EGD + ++FV+ HPIV+WNLVW+ R ++ S+LP
Sbjct: 1631 DPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPG 1690
Query: 1428 LL 1429
L+
Sbjct: 1691 LI 1692
Score = 72.9 bits (171), Expect = 8e-12
Identities = 32/66 (48%), Positives = 44/66 (66%), Gaps = 1/66 (1%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKV-DA 1346
++ + V +SSCS+C C L++DE+IMAGW ADDSNLNT C CG +P L +++ D
Sbjct: 1439 QNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDL 1498
Query: 1347 LRPCPY 1352
RP Y
Sbjct: 1499 RRPGRY 1504
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLG----REARPQDLPPSPTALC 1590
KR S YR+ILFL++ ALG +NID A +EY A D+L + D PPS +
Sbjct: 1794 KRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVME 1853
Query: 1591 CRHYF 1595
CR F
Sbjct: 1854 CRKTF 1858
>BC028057-1|AAH28057.1| 933|Homo sapiens Unknown (protein for
IMAGE:5139692) protein.
Length = 933
Score = 424 bits (1045), Expect = e-117
Identities = 218/508 (42%), Positives = 313/508 (61%), Gaps = 23/508 (4%)
Query: 296 LLSPSNPSDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRP 355
+L +P D +I+++ PL SG F A+TE KILIHSLRP
Sbjct: 366 ILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRP 425
Query: 356 DTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVT 415
LT+V+EA+ S++FPF W CPY+PLCPL LA+VL AP P+++G+DSR+FDLY+PPPDV+
Sbjct: 426 SVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVS 485
Query: 416 CVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNGE 475
CVD+DTN I+ + N++ K+LPK+ K L TL L+ + R R +G
Sbjct: 486 CVDVDTNTISQI-GDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKL-----QQRPRDDGL 539
Query: 476 ATTSL-DRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDPDALF 534
++ D DF K+ ++L+IQEAFL FMA L+GYRSYL PIT+AP+ TD +LF
Sbjct: 540 MDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLF 599
Query: 535 QMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECIEKI---ASGE 591
+ FLRSR+++ Q+F+ +M +TQMF RFIEE SFV D D L FFD+C++K+ SGE
Sbjct: 600 ALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGE 659
Query: 592 ERLLGMDTTNASERTVFLLPPDPP------DPQKTYTYEKFSLDLNLIXXXXXXXXXXXX 645
RL+ +D + SE TVF+ PP+ P +P Y+Y F + N +
Sbjct: 660 VRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNNL-----FERPEGF 714
Query: 646 XXXXXXXXXXXXXXXXXXXPMAKRTKHEVAAAQRLARKASRSPEAWAKCLLGACYSLYFL 705
PM +RTK E+ +A ++A++ S P+ W++CLL CY L+F+
Sbjct: 715 LQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFI 774
Query: 706 TLPSRLMLNRGKEHATLRTAYELLERAAKLKV-PCDEVCYRVMMQLCGIHSFPVMAVQLL 764
LP+ + + K A L+TAY++L++ K+ P DEVCYR++MQLCG + PV+AV++L
Sbjct: 775 CLPAYVKVCHSKVRA-LKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVL 833
Query: 765 FLMKRAGLQPNALTYGCYNRWVLEANWP 792
F M++AG+ PNA+TYG YN+ VLE+ WP
Sbjct: 834 FEMQKAGIDPNAITYGYYNKAVLESTWP 861
Score = 288 bits (707), Expect = 1e-76
Identities = 139/284 (48%), Positives = 183/284 (64%), Gaps = 5/284 (1%)
Query: 16 VVFPTLGETVPDGYELVETTPTGLPADLNHGSMRSPECFLYLRRGRERPPLVDIGVMYDG 75
V+ +LGE VP Y ++ TPTGL ADLN+GS+ P+ +L RRGR++PPL D+GV+YD
Sbjct: 50 VIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDW 109
Query: 76 KERLMADAEMVLESSGGRVANVNNSAA--KTFITYRRAHPGAPCNALXXXXXXXXXXSKG 133
KERL E++ + GR AN++ S + + +ITYRRA N L SKG
Sbjct: 110 KERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKG 169
Query: 134 ECPPHAFCMIAKNLNKGLMGSDVFLCYKKSMNRPPLISYKPDVLFRYPVTDRRSLAFPPS 193
E PPH FC + KNLN + GS V+LCYKKS+ + +SYK ++ RYP D S + P S
Sbjct: 170 ESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYESFSLPES 229
Query: 194 VPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTETQ 253
VPLFCLPMGAT+E WP+N+ P PVFSTFVLT A A EKVYG+A+ FYE Y LTE Q
Sbjct: 230 VPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASA-EKVYGAAIQFYEPYSEENLTEKQ 288
Query: 254 MELLGWRA--NVSQNTHSVHVVKSVCLLSRWPFSDTFERWLLYI 295
LLG + S ++ ++H K +CLLS WPF D F ++L ++
Sbjct: 289 RLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFL 332
>AK091368-1|BAC03648.1| 928|Homo sapiens protein ( Homo sapiens
cDNA FLJ34049 fis, clone FCBBF3000110, weakly similar to
CRAG protein. ).
Length = 928
Score = 424 bits (1045), Expect = e-117
Identities = 218/508 (42%), Positives = 313/508 (61%), Gaps = 23/508 (4%)
Query: 296 LLSPSNPSDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRP 355
+L +P D +I+++ PL SG F A+TE KILIHSLRP
Sbjct: 366 ILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRP 425
Query: 356 DTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVT 415
LT+V+EA+ S++FPF W CPY+PLCPL LA+VL AP P+++G+DSR+FDLY+PPPDV+
Sbjct: 426 SVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVS 485
Query: 416 CVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNGE 475
CVD+DTN I+ + N++ K+LPK+ K L TL L+ + R R +G
Sbjct: 486 CVDVDTNTISQI-GDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKL-----QQRPRDDGL 539
Query: 476 ATTSL-DRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDPDALF 534
++ D DF K+ ++L+IQEAFL FMA L+GYRSYL PIT+AP+ TD +LF
Sbjct: 540 MDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLF 599
Query: 535 QMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECIEKI---ASGE 591
+ FLRSR+++ Q+F+ +M +TQMF RFIEE SFV D D L FFD+C++K+ SGE
Sbjct: 600 ALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGE 659
Query: 592 ERLLGMDTTNASERTVFLLPPDPP------DPQKTYTYEKFSLDLNLIXXXXXXXXXXXX 645
RL+ +D + SE TVF+ PP+ P +P Y+Y F + N +
Sbjct: 660 VRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNNL-----FERPEGF 714
Query: 646 XXXXXXXXXXXXXXXXXXXPMAKRTKHEVAAAQRLARKASRSPEAWAKCLLGACYSLYFL 705
PM +RTK E+ +A ++A++ S P+ W++CLL CY L+F+
Sbjct: 715 LQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFI 774
Query: 706 TLPSRLMLNRGKEHATLRTAYELLERAAKLKV-PCDEVCYRVMMQLCGIHSFPVMAVQLL 764
LP+ + + K A L+TAY++L++ K+ P DEVCYR++MQLCG + PV+AV++L
Sbjct: 775 CLPAYVKVCHSKVRA-LKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVL 833
Query: 765 FLMKRAGLQPNALTYGCYNRWVLEANWP 792
F M++AG+ PNA+TYG YN+ VLE+ WP
Sbjct: 834 FEMQKAGIDPNAITYGYYNKAVLESTWP 861
Score = 288 bits (707), Expect = 1e-76
Identities = 139/284 (48%), Positives = 183/284 (64%), Gaps = 5/284 (1%)
Query: 16 VVFPTLGETVPDGYELVETTPTGLPADLNHGSMRSPECFLYLRRGRERPPLVDIGVMYDG 75
V+ +LGE VP Y ++ TPTGL ADLN+GS+ P+ +L RRGR++PPL D+GV+YD
Sbjct: 50 VIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDW 109
Query: 76 KERLMADAEMVLESSGGRVANVNNSAA--KTFITYRRAHPGAPCNALXXXXXXXXXXSKG 133
KERL E++ + GR AN++ S + + +ITYRRA N L SKG
Sbjct: 110 KERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKG 169
Query: 134 ECPPHAFCMIAKNLNKGLMGSDVFLCYKKSMNRPPLISYKPDVLFRYPVTDRRSLAFPPS 193
E PPH FC + KNLN + GS V+LCYKKS+ + +SYK ++ RYP D S + P S
Sbjct: 170 ESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYESFSLPES 229
Query: 194 VPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTETQ 253
VPLFCLPMGAT+E WP+N+ P PVFSTFVLT A A EKVYG+A+ FYE Y LTE Q
Sbjct: 230 VPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASA-EKVYGAAIQFYEPYSEENLTEKQ 288
Query: 254 MELLGWRA--NVSQNTHSVHVVKSVCLLSRWPFSDTFERWLLYI 295
LLG + S ++ ++H K +CLLS WPF D F ++L ++
Sbjct: 289 RLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFL 332
>AF534403-1|AAQ10514.1| 1865|Homo sapiens c-MYC promoter-binding
protein IRLB protein.
Length = 1865
Score = 424 bits (1045), Expect = e-117
Identities = 218/508 (42%), Positives = 313/508 (61%), Gaps = 23/508 (4%)
Query: 296 LLSPSNPSDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRP 355
+L +P D +I+++ PL SG F A+TE KILIHSLRP
Sbjct: 366 ILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRP 425
Query: 356 DTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVT 415
LT+V+EA+ S++FPF W CPY+PLCPL LA+VL AP P+++G+DSR+FDLY+PPPDV+
Sbjct: 426 SVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVS 485
Query: 416 CVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNGE 475
CVD+DTN I+ + N++ K+LPK+ K L TL L+ + R R +G
Sbjct: 486 CVDVDTNTISQI-GDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKL-----QQRPRDDGL 539
Query: 476 ATTSL-DRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDPDALF 534
++ D DF K+ ++L+IQEAFL FMA L+GYRSYL PIT+AP+ TD +LF
Sbjct: 540 MDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLF 599
Query: 535 QMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECIEKI---ASGE 591
+ FLRSR+++ Q+F+ +M +TQMF RFIEE SFV D D L FFD+C++K+ SGE
Sbjct: 600 ALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGE 659
Query: 592 ERLLGMDTTNASERTVFLLPPDPP------DPQKTYTYEKFSLDLNLIXXXXXXXXXXXX 645
RL+ +D + SE TVF+ PP+ P +P Y+Y F + N +
Sbjct: 660 VRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNNL-----FERPEGF 714
Query: 646 XXXXXXXXXXXXXXXXXXXPMAKRTKHEVAAAQRLARKASRSPEAWAKCLLGACYSLYFL 705
PM +RTK E+ +A ++A++ S P+ W++CLL CY L+F+
Sbjct: 715 LQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFI 774
Query: 706 TLPSRLMLNRGKEHATLRTAYELLERAAKLKV-PCDEVCYRVMMQLCGIHSFPVMAVQLL 764
LP+ + + K A L+TAY++L++ K+ P DEVCYR++MQLCG + PV+AV++L
Sbjct: 775 CLPAYVKVCHSKVRA-LKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVL 833
Query: 765 FLMKRAGLQPNALTYGCYNRWVLEANWP 792
F M++AG+ PNA+TYG YN+ VLE+ WP
Sbjct: 834 FEMQKAGIDPNAITYGYYNKAVLESTWP 861
Score = 288 bits (707), Expect = 1e-76
Identities = 139/284 (48%), Positives = 183/284 (64%), Gaps = 5/284 (1%)
Query: 16 VVFPTLGETVPDGYELVETTPTGLPADLNHGSMRSPECFLYLRRGRERPPLVDIGVMYDG 75
V+ +LGE VP Y ++ TPTGL ADLN+GS+ P+ +L RRGR++PPL D+GV+YD
Sbjct: 50 VIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDW 109
Query: 76 KERLMADAEMVLESSGGRVANVNNSAA--KTFITYRRAHPGAPCNALXXXXXXXXXXSKG 133
KERL E++ + GR AN++ S + + +ITYRRA N L SKG
Sbjct: 110 KERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKG 169
Query: 134 ECPPHAFCMIAKNLNKGLMGSDVFLCYKKSMNRPPLISYKPDVLFRYPVTDRRSLAFPPS 193
E PPH FC + KNLN + GS V+LCYKKS+ + +SYK ++ RYP D S + P S
Sbjct: 170 ESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYESFSLPES 229
Query: 194 VPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTETQ 253
VPLFCLPMGAT+E WP+N+ P PVFSTFVLT A A EKVYG+A+ FYE Y LTE Q
Sbjct: 230 VPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASA-EKVYGAAIQFYEPYSEENLTEKQ 288
Query: 254 MELLGWRA--NVSQNTHSVHVVKSVCLLSRWPFSDTFERWLLYI 295
LLG + S ++ ++H K +CLLS WPF D F ++L ++
Sbjct: 289 RLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFL 332
Score = 79.0 bits (186), Expect = 1e-13
Identities = 32/62 (51%), Positives = 47/62 (75%)
Query: 1368 ETLTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPD 1427
+ +TVPYL+PLV+ KE ES+L EGD + ++FV+ HPIV+WNLVW+ R ++ S+LP
Sbjct: 1633 DPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPG 1692
Query: 1428 LL 1429
L+
Sbjct: 1693 LI 1694
Score = 72.9 bits (171), Expect = 8e-12
Identities = 32/66 (48%), Positives = 44/66 (66%), Gaps = 1/66 (1%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKV-DA 1346
++ + V +SSCS+C C L++DE+IMAGW ADDSNLNT C CG +P L +++ D
Sbjct: 1441 QNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDL 1500
Query: 1347 LRPCPY 1352
RP Y
Sbjct: 1501 RRPGRY 1506
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLG----REARPQDLPPSPTALC 1590
KR S YR+ILFL++ ALG +NID A +EY A D+L + D PPS +
Sbjct: 1796 KRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVME 1855
Query: 1591 CRHYF 1595
CR F
Sbjct: 1856 CRKTF 1860
>AL832602-1|CAD89960.1| 1831|Homo sapiens hypothetical protein
protein.
Length = 1831
Score = 424 bits (1044), Expect = e-117
Identities = 218/508 (42%), Positives = 313/508 (61%), Gaps = 23/508 (4%)
Query: 296 LLSPSNPSDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRP 355
+L +P D +I+++ PL SG F A+TE KILIHSLRP
Sbjct: 334 ILVQLSPHDNLILSQPVPSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRP 393
Query: 356 DTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVT 415
LT+V+EA+ S++FPF W CPY+PLCPL LA+VL AP P+++G+DSR+FDLY+PPPDV+
Sbjct: 394 SVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVS 453
Query: 416 CVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNGE 475
CVD+DTN I+ + N++ K+LPK+ K L TL L+ + R R +G
Sbjct: 454 CVDVDTNTISQI-GDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKL-----QQRPRDDGL 507
Query: 476 ATTSL-DRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDPDALF 534
++ D DF K+ ++L+IQEAFL FMA L+GYRSYL PIT+AP+ TD +LF
Sbjct: 508 MDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLF 567
Query: 535 QMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECIEKI---ASGE 591
+ FLRSR+++ Q+F+ +M +TQMF RFIEE SFV D D L FFD+C++K+ SGE
Sbjct: 568 ALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGE 627
Query: 592 ERLLGMDTTNASERTVFLLPPDPP------DPQKTYTYEKFSLDLNLIXXXXXXXXXXXX 645
RL+ +D + SE TVF+ PP+ P +P Y+Y F + N +
Sbjct: 628 VRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNNL-----FERPEGF 682
Query: 646 XXXXXXXXXXXXXXXXXXXPMAKRTKHEVAAAQRLARKASRSPEAWAKCLLGACYSLYFL 705
PM +RTK E+ +A ++A++ S P+ W++CLL CY L+F+
Sbjct: 683 LQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFI 742
Query: 706 TLPSRLMLNRGKEHATLRTAYELLERAAKLKV-PCDEVCYRVMMQLCGIHSFPVMAVQLL 764
LP+ + + K A L+TAY++L++ K+ P DEVCYR++MQLCG + PV+AV++L
Sbjct: 743 CLPAYVKVCHSKVRA-LKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVL 801
Query: 765 FLMKRAGLQPNALTYGCYNRWVLEANWP 792
F M++AG+ PNA+TYG YN+ VLE+ WP
Sbjct: 802 FEMQKAGIDPNAITYGYYNKAVLESTWP 829
Score = 288 bits (707), Expect = 1e-76
Identities = 139/284 (48%), Positives = 183/284 (64%), Gaps = 5/284 (1%)
Query: 16 VVFPTLGETVPDGYELVETTPTGLPADLNHGSMRSPECFLYLRRGRERPPLVDIGVMYDG 75
V+ +LGE VP Y ++ TPTGL ADLN+GS+ P+ +L RRGR++PPL D+GV+YD
Sbjct: 18 VIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDW 77
Query: 76 KERLMADAEMVLESSGGRVANVNNSAA--KTFITYRRAHPGAPCNALXXXXXXXXXXSKG 133
KERL E++ + GR AN++ S + + +ITYRRA N L SKG
Sbjct: 78 KERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKG 137
Query: 134 ECPPHAFCMIAKNLNKGLMGSDVFLCYKKSMNRPPLISYKPDVLFRYPVTDRRSLAFPPS 193
E PPH FC + KNLN + GS V+LCYKKS+ + +SYK ++ RYP D S + P S
Sbjct: 138 ESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYESFSLPES 197
Query: 194 VPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTETQ 253
VPLFCLPMGAT+E WP+N+ P PVFSTFVLT A A EKVYG+A+ FYE Y LTE Q
Sbjct: 198 VPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASA-EKVYGAAIQFYEPYSEENLTEKQ 256
Query: 254 MELLGWRA--NVSQNTHSVHVVKSVCLLSRWPFSDTFERWLLYI 295
LLG + S ++ ++H K +CLLS WPF D F ++L ++
Sbjct: 257 RLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFL 300
Score = 79.0 bits (186), Expect = 1e-13
Identities = 32/62 (51%), Positives = 47/62 (75%)
Query: 1368 ETLTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPD 1427
+ +TVPYL+PLV+ KE ES+L EGD + ++FV+ HPIV+WNLVW+ R ++ S+LP
Sbjct: 1599 DPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPG 1658
Query: 1428 LL 1429
L+
Sbjct: 1659 LI 1660
Score = 72.9 bits (171), Expect = 8e-12
Identities = 32/66 (48%), Positives = 44/66 (66%), Gaps = 1/66 (1%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKV-DA 1346
++ + V +SSCS+C C L++DE+IMAGW ADDSNLNT C CG +P L +++ D
Sbjct: 1407 QNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDL 1466
Query: 1347 LRPCPY 1352
RP Y
Sbjct: 1467 RRPGRY 1472
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLG----REARPQDLPPSPTALC 1590
KR S YR+ILFL++ ALG +NID A +EY A D+L + D PPS +
Sbjct: 1762 KRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVME 1821
Query: 1591 CRHYF 1595
CR F
Sbjct: 1822 CRKTF 1826
>AL391834-11|CAM21148.1| 1673|Homo sapiens DENN/MADD domain
containing 4C protein.
Length = 1673
Score = 414 bits (1020), Expect = e-114
Identities = 224/511 (43%), Positives = 312/511 (61%), Gaps = 35/511 (6%)
Query: 304 DRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRPDTLTAVSE 363
D +I+++ PL SGA+F + E KIL+HSLRP LT V+E
Sbjct: 138 DALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRPAVLTGVAE 197
Query: 364 AVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVTCVDLDTNN 423
AV +++FPF+WQCPYIPLCPL LA VL APLP+++GVDSR+FDL++PP DV C+DLDTN
Sbjct: 198 AVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNM 257
Query: 424 ITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNGEATTSLDRD 483
+ V + ++ N++ K LPK+ K L TL+ LY + S +H ++ + T ++ D
Sbjct: 258 LYVSD-EKKNMNWKQLPKKPCKNLLSTLKKLYPQL---SSVHQKTQEG-SAIDMTPIEAD 312
Query: 484 FQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSR 543
F +KK LE++IQEAFLRFMA L+GYR+YL PIT+AP+ T D+LF FL+SR
Sbjct: 313 FSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQGFLKSR 372
Query: 544 EKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECIEKI---------------A 588
++ +F+TL+ +TQ+F RFIEE SFV D D GL FFD+CIEK+ +
Sbjct: 373 DRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDS 432
Query: 589 SGEERLLGMDTTNASERTVFLLPPDPP-----DPQKTYTYEKF-SLDLNLIXXXXXXXXX 642
+ + RL+ +D + SE TVF++PP+PP D Y+Y+ F LDL L
Sbjct: 433 AEDTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLC 492
Query: 643 XXXXXXXXXXXXXXXXXXXXXXPMAKRTKHEVAAAQRLARKASRSPEAWAKCLLGACYSL 702
MAKRTK E+ A +LA++ +P WAKCL CYSL
Sbjct: 493 FSRHPTGNSITKSPPL-------MAKRTKQEIKTAHKLAKRCYTNPPQWAKCLFSHCYSL 545
Query: 703 YFLTLPSRLMLNRGKEHATLRTAYELLERAAKLKV-PCDEVCYRVMMQLCGIHSFPVMAV 761
+F+ LP+ + ++ K A L+ AY++L + K V P DEVCYRV+MQLCG+ PV+AV
Sbjct: 546 WFICLPAYVRVSHPKVRA-LQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAV 604
Query: 762 QLLFLMKRAGLQPNALTYGCYNRWVLEANWP 792
++LF MK A ++PNA+TYG YN+ VLE+ WP
Sbjct: 605 RVLFEMKTARIKPNAITYGYYNKVVLESPWP 635
Score = 89.0 bits (211), Expect = 1e-16
Identities = 48/105 (45%), Positives = 65/105 (61%), Gaps = 4/105 (3%)
Query: 201 MGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTETQMELLGWR 260
MGAT+E W P PVFSTFVLT + A +KVYG+A+ FYE Y L+E Q+ LG
Sbjct: 1 MGATIECWDPETKYPLPVFSTFVLTGSSA-KKVYGAAIQFYEPYSRELLSEKQLMHLGLL 59
Query: 261 ANVSQN--THSVHVVKSVCLLSRWPFSDTFERWLLYIL-LSPSNP 302
V + + S++ K +CLLS WPF + F ++L++I LS S P
Sbjct: 60 TPVERKMVSKSINTNKCICLLSHWPFFEAFRKFLMFIYKLSVSGP 104
Score = 80.2 bits (189), Expect = 6e-14
Identities = 32/60 (53%), Positives = 45/60 (75%)
Query: 1370 LTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
++VPYL+PLVLRKE ES+L EGD + S F+ HPI++WNLVW+ R ++ S+LP L+
Sbjct: 1447 VSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLI 1506
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 1245 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 1304
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 1305 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 1341
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLGREARPQ----DLPPSPTALC 1590
KR S YR+ILFL++ +LG +NID A EY A + L E + D PPS +
Sbjct: 1604 KRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEW 1663
Query: 1591 CRHYF 1595
CR F
Sbjct: 1664 CRKCF 1668
>AL161909-3|CAH70581.2| 1673|Homo sapiens DENN/MADD domain
containing 4C protein.
Length = 1673
Score = 414 bits (1020), Expect = e-114
Identities = 224/511 (43%), Positives = 312/511 (61%), Gaps = 35/511 (6%)
Query: 304 DRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRPDTLTAVSE 363
D +I+++ PL SGA+F + E KIL+HSLRP LT V+E
Sbjct: 138 DALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRPAVLTGVAE 197
Query: 364 AVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVTCVDLDTNN 423
AV +++FPF+WQCPYIPLCPL LA VL APLP+++GVDSR+FDL++PP DV C+DLDTN
Sbjct: 198 AVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNM 257
Query: 424 ITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNGEATTSLDRD 483
+ V + ++ N++ K LPK+ K L TL+ LY + S +H ++ + T ++ D
Sbjct: 258 LYVSD-EKKNMNWKQLPKKPCKNLLSTLKKLYPQL---SSVHQKTQEG-SAIDMTPIEAD 312
Query: 484 FQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSR 543
F +KK LE++IQEAFLRFMA L+GYR+YL PIT+AP+ T D+LF FL+SR
Sbjct: 313 FSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQGFLKSR 372
Query: 544 EKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECIEKI---------------A 588
++ +F+TL+ +TQ+F RFIEE SFV D D GL FFD+CIEK+ +
Sbjct: 373 DRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDS 432
Query: 589 SGEERLLGMDTTNASERTVFLLPPDPP-----DPQKTYTYEKF-SLDLNLIXXXXXXXXX 642
+ + RL+ +D + SE TVF++PP+PP D Y+Y+ F LDL L
Sbjct: 433 AEDTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLC 492
Query: 643 XXXXXXXXXXXXXXXXXXXXXXPMAKRTKHEVAAAQRLARKASRSPEAWAKCLLGACYSL 702
MAKRTK E+ A +LA++ +P WAKCL CYSL
Sbjct: 493 FSRHPTGNSITKSPPL-------MAKRTKQEIKTAHKLAKRCYTNPPQWAKCLFSHCYSL 545
Query: 703 YFLTLPSRLMLNRGKEHATLRTAYELLERAAKLKV-PCDEVCYRVMMQLCGIHSFPVMAV 761
+F+ LP+ + ++ K A L+ AY++L + K V P DEVCYRV+MQLCG+ PV+AV
Sbjct: 546 WFICLPAYVRVSHPKVRA-LQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAV 604
Query: 762 QLLFLMKRAGLQPNALTYGCYNRWVLEANWP 792
++LF MK A ++PNA+TYG YN+ VLE+ WP
Sbjct: 605 RVLFEMKTARIKPNAITYGYYNKVVLESPWP 635
Score = 89.0 bits (211), Expect = 1e-16
Identities = 48/105 (45%), Positives = 65/105 (61%), Gaps = 4/105 (3%)
Query: 201 MGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTETQMELLGWR 260
MGAT+E W P PVFSTFVLT + A +KVYG+A+ FYE Y L+E Q+ LG
Sbjct: 1 MGATIECWDPETKYPLPVFSTFVLTGSSA-KKVYGAAIQFYEPYSRELLSEKQLMHLGLL 59
Query: 261 ANVSQN--THSVHVVKSVCLLSRWPFSDTFERWLLYIL-LSPSNP 302
V + + S++ K +CLLS WPF + F ++L++I LS S P
Sbjct: 60 TPVERKMVSKSINTNKCICLLSHWPFFEAFRKFLMFIYKLSVSGP 104
Score = 80.2 bits (189), Expect = 6e-14
Identities = 32/60 (53%), Positives = 45/60 (75%)
Query: 1370 LTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
++VPYL+PLVLRKE ES+L EGD + S F+ HPI++WNLVW+ R ++ S+LP L+
Sbjct: 1447 VSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLI 1506
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 1245 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 1304
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 1305 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 1341
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLGREARPQ----DLPPSPTALC 1590
KR S YR+ILFL++ +LG +NID A EY A + L E + D PPS +
Sbjct: 1604 KRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEW 1663
Query: 1591 CRHYF 1595
CR F
Sbjct: 1664 CRKCF 1668
>AK125842-1|BAC86313.1| 1557|Homo sapiens protein ( Homo sapiens
cDNA FLJ43854 fis, clone TESTI4007064. ).
Length = 1557
Score = 413 bits (1016), Expect = e-114
Identities = 223/511 (43%), Positives = 311/511 (60%), Gaps = 35/511 (6%)
Query: 304 DRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRPDTLTAVSE 363
D +I+++ PL SGA+F + E KIL+HSLRP LT V+E
Sbjct: 22 DALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRPAVLTGVAE 81
Query: 364 AVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVTCVDLDTNN 423
AV +++FPF+WQCPYIPLCPL LA VL APLP+++GVDSR+FDL++PP DV C+DLDTN
Sbjct: 82 AVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNM 141
Query: 424 ITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNGEATTSLDRD 483
+ V + ++ N++ K LPK+ K L TL+ LY + S +H ++ + T ++ D
Sbjct: 142 LYVSD-EKKNMNWKQLPKKPCKNLLSTLKKLYPQL---SSVHQKTQEG-SAIDMTPIEAD 196
Query: 484 FQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSR 543
F +KK LE++IQEAFLRFMA L+GYR+YL PIT+AP+ T D+LF FL+SR
Sbjct: 197 FSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQGFLKSR 256
Query: 544 EKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECIEKI---------------A 588
++ +F+TL+ +TQ+F RFIEE SFV D D GL FFD+CIEK+ +
Sbjct: 257 DRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDS 316
Query: 589 SGEERLLGMDTTNASERTVFLLPPDPP-----DPQKTYTYEKF-SLDLNLIXXXXXXXXX 642
+ + RL+ +D + E TVF++PP+PP D Y+Y+ F LDL L
Sbjct: 317 AEDTRLIELDDSQKGEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLC 376
Query: 643 XXXXXXXXXXXXXXXXXXXXXXPMAKRTKHEVAAAQRLARKASRSPEAWAKCLLGACYSL 702
MAKRTK E+ A +LA++ +P WAKCL CYSL
Sbjct: 377 FSRHPTGNSITKSPPL-------MAKRTKQEIKTAHKLAKRCYTNPPQWAKCLFSHCYSL 429
Query: 703 YFLTLPSRLMLNRGKEHATLRTAYELLERAAKLKV-PCDEVCYRVMMQLCGIHSFPVMAV 761
+F+ LP+ + ++ K A L+ AY++L + K V P DEVCYRV+MQLCG+ PV+AV
Sbjct: 430 WFICLPAYVRVSHPKVRA-LQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAV 488
Query: 762 QLLFLMKRAGLQPNALTYGCYNRWVLEANWP 792
++LF MK A ++PNA+TYG YN+ VLE+ WP
Sbjct: 489 RVLFEMKTARIKPNAITYGYYNKVVLESPWP 519
Score = 80.2 bits (189), Expect = 6e-14
Identities = 32/60 (53%), Positives = 45/60 (75%)
Query: 1370 LTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
++VPYL+PLVLRKE ES+L EGD + S F+ HPI++WNLVW+ R ++ S+LP L+
Sbjct: 1331 VSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLI 1390
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 1129 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 1188
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 1189 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 1225
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLGREARPQ----DLPPSPTALC 1590
KR S YR+ILFL++ +LG +NID A EY A + L E + D PPS +
Sbjct: 1488 KRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEW 1547
Query: 1591 CRHYF 1595
CR F
Sbjct: 1548 CRKCF 1552
>AL358472-2|CAI14016.1| 1384|Homo sapiens DENN/MADD domain
containing 4B protein.
Length = 1384
Score = 368 bits (905), Expect = e-100
Identities = 203/514 (39%), Positives = 298/514 (57%), Gaps = 29/514 (5%)
Query: 296 LLSPSNPSDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRP 355
+L +P D +++ + PL SGASF Q +TE K+L+HSLRP
Sbjct: 259 ILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRP 318
Query: 356 DTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVT 415
D LT+V EA+ S++FP WQCPYIPLCPL LA+VL AP+P+++G+ S +FDL++PP DV
Sbjct: 319 DLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVI 378
Query: 416 CVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNG- 474
CVDLDTN + E ++ +S + LP+R K L TL LY + Y G
Sbjct: 379 CVDLDTNTLFQTE-EKKLLSPRTLPRRPYKVLLATLTNLYQQL----------DQTYTGP 427
Query: 475 EATTSLD---RDFQKRKKEQA-LELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDP 530
E SL+ D++ +A LE ++Q AFLRFMAC L+GYR +L P+T+AP+ G D
Sbjct: 428 EEEASLEFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDV 487
Query: 531 DALFQMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECIEKIASG 590
D LF + FL+SRE++ + ++ ++ TQMF++FIEE SF L FFD C+EK+
Sbjct: 488 DNLFFLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPE 547
Query: 591 EER-----LLGMDTTNASERTVFLLPPDPPD-PQKTYTYEKFSLDLNLIXXXXXXXXXXX 644
+E+ L+ ++ + SE TVF+ PP+ P P+ + + ++ D
Sbjct: 548 QEKPEPTPLVELEELSGSELTVFITPPEEPALPEGSESTPQYCYD---GFPELRAELFES 604
Query: 645 XXXXXXXXXXXXXXXXXXXXPMAKRTKHEVAAAQRLARKASRSPEAWAKCLLGACYSLYF 704
P +RTK E+ AQR+A+K++ PE WA+CLLG CY L+F
Sbjct: 605 LQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWF 664
Query: 705 LTLPSRLMLNRGKEHATLRTAYELLER--AAKLKVPCDEVCYRVMMQLCGIHSFPVMAVQ 762
L LP+ + + A L TAY +L + + K+ +P DEVCYRV+MQLC + PV++V+
Sbjct: 665 LCLPAYVRSAPSRVQA-LHTAYHVLRQMESGKVVLP-DEVCYRVLMQLCSHYGQPVLSVR 722
Query: 763 LLFLMKRAGLQPNALTYGCYNRWVLEANWPKDMP 796
++ M++AG+ PN +TYG YN+ VLE+ WP P
Sbjct: 723 VMLEMRQAGIVPNTITYGYYNKAVLESKWPSGTP 756
Score = 73.3 bits (172), Expect = 6e-12
Identities = 34/69 (49%), Positives = 44/69 (63%)
Query: 1281 TSAPVKPESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLL 1340
+ P +S + + +SSCS C C +L+YDE+IMAGWA DDSNLNT C C VPLL
Sbjct: 1027 SDTPGSFQSPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLL 1086
Query: 1341 TVKVDALRP 1349
+V+ RP
Sbjct: 1087 SVQTLDSRP 1095
Score = 65.3 bits (152), Expect = 2e-09
Identities = 27/56 (48%), Positives = 38/56 (67%)
Query: 1374 YLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
YL+PLVLRKE ES++ EG L E +HPI++WNL+W+ +R + S LP L+
Sbjct: 1154 YLSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLV 1209
Score = 46.4 bits (105), Expect = 8e-04
Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 6/61 (9%)
Query: 1541 YRDILFLAMAALGEQNIDFIALQREYTRALDQLGREARPQDL------PPSPTALCCRHY 1594
YR+ILFL MAALG+ ++D +A ++Y A ++L ++L P+P A+ CR
Sbjct: 1318 YREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKC 1377
Query: 1595 F 1595
F
Sbjct: 1378 F 1378
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 240 FYESYPYSELTETQMELLGWRANVSQNT----HSVHVVKSVCLLSRWPFSDTFERWLLYI 295
FYE++P + L+E Q LG + V + +V +++ +LSRWP F +L ++
Sbjct: 166 FYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFL 225
>AB007945-1|BAA32321.3| 1626|Homo sapiens KIAA0476 protein protein.
Length = 1626
Score = 368 bits (905), Expect = e-100
Identities = 203/514 (39%), Positives = 298/514 (57%), Gaps = 29/514 (5%)
Query: 296 LLSPSNPSDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRP 355
+L +P D +++ + PL SGASF Q +TE K+L+HSLRP
Sbjct: 501 ILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRP 560
Query: 356 DTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVT 415
D LT+V EA+ S++FP WQCPYIPLCPL LA+VL AP+P+++G+ S +FDL++PP DV
Sbjct: 561 DLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVI 620
Query: 416 CVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNG- 474
CVDLDTN + E ++ +S + LP+R K L TL LY + Y G
Sbjct: 621 CVDLDTNTLFQTE-EKKLLSPRTLPRRPYKVLLATLTNLYQQL----------DQTYTGP 669
Query: 475 EATTSLD---RDFQKRKKEQA-LELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDP 530
E SL+ D++ +A LE ++Q AFLRFMAC L+GYR +L P+T+AP+ G D
Sbjct: 670 EEEASLEFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDV 729
Query: 531 DALFQMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECIEKIASG 590
D LF + FL+SRE++ + ++ ++ TQMF++FIEE SF L FFD C+EK+
Sbjct: 730 DNLFFLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPE 789
Query: 591 EER-----LLGMDTTNASERTVFLLPPDPPD-PQKTYTYEKFSLDLNLIXXXXXXXXXXX 644
+E+ L+ ++ + SE TVF+ PP+ P P+ + + ++ D
Sbjct: 790 QEKPEPTPLVELEELSGSELTVFITPPEEPALPEGSESTPQYCYD---GFPELRAELFES 846
Query: 645 XXXXXXXXXXXXXXXXXXXXPMAKRTKHEVAAAQRLARKASRSPEAWAKCLLGACYSLYF 704
P +RTK E+ AQR+A+K++ PE WA+CLLG CY L+F
Sbjct: 847 LQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWF 906
Query: 705 LTLPSRLMLNRGKEHATLRTAYELLER--AAKLKVPCDEVCYRVMMQLCGIHSFPVMAVQ 762
L LP+ + + A L TAY +L + + K+ +P DEVCYRV+MQLC + PV++V+
Sbjct: 907 LCLPAYVRSAPSRVQA-LHTAYHVLRQMESGKVVLP-DEVCYRVLMQLCSHYGQPVLSVR 964
Query: 763 LLFLMKRAGLQPNALTYGCYNRWVLEANWPKDMP 796
++ M++AG+ PN +TYG YN+ VLE+ WP P
Sbjct: 965 VMLEMRQAGIVPNTITYGYYNKAVLESKWPSGTP 998
Score = 219 bits (534), Expect = 9e-56
Identities = 112/287 (39%), Positives = 167/287 (58%), Gaps = 8/287 (2%)
Query: 16 VVFPTLGETVPDGYELVETTPTGLPADLNHGSMRSPECFLYLRRGRERPPLVDIGVMYDG 75
V+ LGE VP GY ++ + G P +L+ G + + + RRGR++PPLV++GV+Y+G
Sbjct: 182 VIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPVICYRRGRDKPPLVELGVLYEG 241
Query: 76 KERLMADAEMVLESSGGRVANV---NNSAAKTFITYRRAHPGAPCNALXXXXXXXXXXSK 132
KER +++ + AN+ +T++TYRRA GA +AL SK
Sbjct: 242 KERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRAAEGAGLHALGITDLCLVLPSK 301
Query: 133 GECPPHAFCMIAKNLNKGLMGSDVFLCYKKSMNRPPLISYKPDVLFRYPVTDRRSLAFPP 192
GE PH +C + +NLN G+ G V+LCYK + + + Y+ ++L RYP D + P
Sbjct: 302 GEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNEAFPLPE 361
Query: 193 SVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTET 252
SVP+FCLPMGAT+E WP P PVFSTFVLT A A +KVYG+A+ FYE++P + L+E
Sbjct: 362 SVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGA-AGDKVYGAALQFYEAFPRARLSER 420
Query: 253 QMELLGWRANVSQNT----HSVHVVKSVCLLSRWPFSDTFERWLLYI 295
Q LG + V + +V +++ +LSRWP F +L ++
Sbjct: 421 QARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFL 467
Score = 73.3 bits (172), Expect = 6e-12
Identities = 34/69 (49%), Positives = 44/69 (63%)
Query: 1281 TSAPVKPESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLL 1340
+ P +S + + +SSCS C C +L+YDE+IMAGWA DDSNLNT C C VPLL
Sbjct: 1269 SDTPGSFQSPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLL 1328
Query: 1341 TVKVDALRP 1349
+V+ RP
Sbjct: 1329 SVQTLDSRP 1337
Score = 65.3 bits (152), Expect = 2e-09
Identities = 27/56 (48%), Positives = 38/56 (67%)
Query: 1374 YLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
YL+PLVLRKE ES++ EG L E +HPI++WNL+W+ +R + S LP L+
Sbjct: 1396 YLSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLV 1451
Score = 46.4 bits (105), Expect = 8e-04
Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 6/61 (9%)
Query: 1541 YRDILFLAMAALGEQNIDFIALQREYTRALDQLGREARPQDL------PPSPTALCCRHY 1594
YR+ILFL MAALG+ ++D +A ++Y A ++L ++L P+P A+ CR
Sbjct: 1560 YREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKC 1619
Query: 1595 F 1595
F
Sbjct: 1620 F 1620
>AL391834-1|CAM21138.1| 1146|Homo sapiens DENN/MADD domain
containing 4C protein.
Length = 1146
Score = 83.0 bits (196), Expect = 8e-15
Identities = 35/55 (63%), Positives = 45/55 (81%)
Query: 738 PCDEVCYRVMMQLCGIHSFPVMAVQLLFLMKRAGLQPNALTYGCYNRWVLEANWP 792
P DEVCYRV+MQLCG+ PV+AV++LF MK A ++PNA+TYG YN+ VLE+ WP
Sbjct: 8 PLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTARIKPNAITYGYYNKVVLESPWP 62
Score = 80.2 bits (189), Expect = 6e-14
Identities = 32/60 (53%), Positives = 45/60 (75%)
Query: 1370 LTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
++VPYL+PLVLRKE ES+L EGD + S F+ HPI++WNLVW+ R ++ S+LP L+
Sbjct: 920 VSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLI 979
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 718 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 777
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 778 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 814
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLGREARPQ----DLPPSPTALC 1590
KR S YR+ILFL++ +LG +NID A EY A + L E + D PPS +
Sbjct: 1077 KRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEW 1136
Query: 1591 CRHYF 1595
CR F
Sbjct: 1137 CRKCF 1141
>AL391834-3|CAM21140.1| 670|Homo sapiens DENN/MADD domain containing
4C protein.
Length = 670
Score = 80.2 bits (189), Expect = 6e-14
Identities = 32/60 (53%), Positives = 45/60 (75%)
Query: 1370 LTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
++VPYL+PLVLRKE ES+L EGD + S F+ HPI++WNLVW+ R ++ S+LP L+
Sbjct: 444 VSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLI 503
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 242 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 301
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 302 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 338
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLGREARPQ----DLPPSPTALC 1590
KR S YR+ILFL++ +LG +NID A EY A + L E + D PPS +
Sbjct: 601 KRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEW 660
Query: 1591 CRHYF 1595
CR F
Sbjct: 661 CRKCF 665
>AL391834-2|CAM21139.1| 791|Homo sapiens DENN/MADD domain containing
4C protein.
Length = 791
Score = 80.2 bits (189), Expect = 6e-14
Identities = 32/60 (53%), Positives = 45/60 (75%)
Query: 1370 LTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
++VPYL+PLVLRKE ES+L EGD + S F+ HPI++WNLVW+ R ++ S+LP L+
Sbjct: 629 VSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLI 688
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 427 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 486
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 487 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 523
>AK025705-1|BAB15221.1| 791|Homo sapiens protein ( Homo sapiens cDNA:
FLJ22052 fis, clone HEP09477. ).
Length = 791
Score = 80.2 bits (189), Expect = 6e-14
Identities = 32/60 (53%), Positives = 45/60 (75%)
Query: 1370 LTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
++VPYL+PLVLRKE ES+L EGD + S F+ HPI++WNLVW+ R ++ S+LP L+
Sbjct: 629 VSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLI 688
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 427 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 486
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 487 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 523
>AK002020-1|BAA92039.1| 324|Homo sapiens protein ( Homo sapiens cDNA
FLJ11158 fis, clone PLACE1006962. ).
Length = 324
Score = 80.2 bits (189), Expect = 6e-14
Identities = 32/60 (53%), Positives = 45/60 (75%)
Query: 1370 LTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
++VPYL+PLVLRKE ES+L EGD + S F+ HPI++WNLVW+ R ++ S+LP L+
Sbjct: 98 VSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLI 157
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLGREARPQ----DLPPSPTALC 1590
KR S YR+ILFL++ +LG +NID A EY A + L E + D PPS +
Sbjct: 255 KRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEW 314
Query: 1591 CRHYF 1595
CR F
Sbjct: 315 CRKCF 319
>AK001046-1|BAA91478.1| 452|Homo sapiens protein ( Homo sapiens cDNA
FLJ10184 fis, clone HEMBA1004289. ).
Length = 452
Score = 80.2 bits (189), Expect = 6e-14
Identities = 32/60 (53%), Positives = 45/60 (75%)
Query: 1370 LTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
++VPYL+PLVLRKE ES+L EGD + S F+ HPI++WNLVW+ R ++ S+LP L+
Sbjct: 226 VSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLI 285
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 24 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 83
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 84 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 120
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLGREARPQ----DLPPSPTALC 1590
KR S YR+ILFL++ +LG +NID A EY A + L E + D PPS +
Sbjct: 383 KRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEW 442
Query: 1591 CRHYF 1595
CR F
Sbjct: 443 CRKCF 447
>AL391834-4|CAM21141.1| 258|Homo sapiens DENN/MADD domain containing
4C protein.
Length = 258
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 116 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 175
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 176 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 212
>AK000693-1|BAA91324.1| 452|Homo sapiens protein ( Homo sapiens cDNA
FLJ20686 fis, clone KAIA3040. ).
Length = 452
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 24 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 83
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 84 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 120
Score = 79.8 bits (188), Expect = 7e-14
Identities = 32/60 (53%), Positives = 45/60 (75%)
Query: 1370 LTVPYLNPLVLRKEFESVLGREGDSCLIESEFVESHPIVYWNLVWFLERANIESHLPDLL 1429
++VPYL+PLVLRKE ES+L EGD + S F+ HPI++WNLVW+ R ++ S+LP L+
Sbjct: 226 VSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPRLI 285
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLGREARPQ----DLPPSPTALC 1590
KR S YR+ILFL++ +LG +NID A EY A + L E + D PPS +
Sbjct: 383 KRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEW 442
Query: 1591 CRHYF 1595
CR F
Sbjct: 443 CRKCF 447
>AK000627-1|BAA91294.1| 258|Homo sapiens protein ( Homo sapiens cDNA
FLJ20620 fis, clone KAT04876. ).
Length = 258
Score = 79.8 bits (188), Expect = 7e-14
Identities = 41/100 (41%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 1288 ESVGVSVHMSSCSQCHQCLALLYDEDIMAGWAADDSNLNTRCTACGRHTVPLLTVKVDAL 1347
++ + V MSSCSQC C AL+YDE+IMAGW ADDSNLNT C C + +PLL ++ L
Sbjct: 116 QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDL 175
Query: 1348 RPCPYCDIKPHIMRTGQTQTETLTVPYLNPLVLRKEFESV 1387
R +KP T ++ ++P N + K S+
Sbjct: 176 RGSASFFLKP---STSGDSLQSGSIPLANESLEHKPVSSL 212
>BC101466-1|AAI01467.1| 1849|Homo sapiens SET binding factor 2
protein.
Length = 1849
Score = 78.6 bits (185), Expect = 2e-13
Identities = 72/242 (29%), Positives = 101/242 (41%), Gaps = 26/242 (10%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+TE K+L HS L+ A+ SL+FP K+ PYIP+ P L EVL +P P++IGV S
Sbjct: 219 LTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHS 278
Query: 403 RFFDLYEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPAS 462
F DV DLD I + E I + LP+ L QT L + P
Sbjct: 279 VFKTDVHELLDVIIADLDGGTIKIPEC----IHLSSLPE---PLLHQTQSALSLILHPDL 331
Query: 463 PIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKA 522
+ + T+L + L+ +++ FLR A QGYRS L I
Sbjct: 332 EV----ADHAFPPPRTALSH-------SKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRI- 379
Query: 523 PTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDE 582
+P F FL R + F T ++ F F+ E Y + FDE
Sbjct: 380 ----HAEPVIHFHKTAFLGQRGLVENDFLTKVLSGMAFAGFVSERGPPY---RSCDLFDE 432
Query: 583 CI 584
+
Sbjct: 433 LV 434
Score = 44.8 bits (101), Expect = 0.003
Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query: 176 VLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYG 235
++ R+P D FP + LFC P G W + +P F VLT D +++ Y
Sbjct: 27 IIQRFPQKDWDDTPFPQGIELFCQPGG-----WQLSRERKQPTFFVVVLTDID-SDRHYC 80
Query: 236 SAVTFYESYPYSELTETQMELLGWRANVSQ--NTHSVHVVKSVCLLSRWPFSDTFERWL 292
S +TFYE+ L T+ E + A VS V KS+ L+SR + + F L
Sbjct: 81 SCLTFYEA--EINLQGTKKEEIEGEAKVSGLIQPAEVFAPKSLVLVSRLYYPEIFRACL 137
>AY234241-1|AAO62733.1| 1849|Homo sapiens SET binding factor 2
protein.
Length = 1849
Score = 78.6 bits (185), Expect = 2e-13
Identities = 72/242 (29%), Positives = 101/242 (41%), Gaps = 26/242 (10%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+TE K+L HS L+ A+ SL+FP K+ PYIP+ P L EVL +P P++IGV S
Sbjct: 219 LTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHS 278
Query: 403 RFFDLYEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPAS 462
F DV DLD I + E I + LP+ L QT L + P
Sbjct: 279 VFKTDVHELLDVIIADLDGGTIKIPEC----IHLSSLPE---PLLHQTQSALSLILHPDL 331
Query: 463 PIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKA 522
+ + T+L + L+ +++ FLR A QGYRS L I
Sbjct: 332 EV----ADHAFPPPRTALSH-------SKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRI- 379
Query: 523 PTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDE 582
+P F FL R + F T ++ F F+ E Y + FDE
Sbjct: 380 ----HAEPVIHFHKTAFLGQRGLVENDFLTKVLSGMAFAGFVSERGPPY---RSCDLFDE 432
Query: 583 CI 584
+
Sbjct: 433 LV 434
Score = 44.8 bits (101), Expect = 0.003
Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query: 176 VLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYG 235
++ R+P D FP + LFC P G W + +P F VLT D +++ Y
Sbjct: 27 IIQRFPQKDWDDTPFPQGIELFCQPGG-----WQLSRERKQPTFFVVVLTDID-SDRHYC 80
Query: 236 SAVTFYESYPYSELTETQMELLGWRANVSQ--NTHSVHVVKSVCLLSRWPFSDTFERWL 292
S +TFYE+ L T+ E + A VS V KS+ L+SR + + F L
Sbjct: 81 SCLTFYEA--EINLQGTKKEEIEGEAKVSGLIQPAEVFAPKSLVLVSRLYYPEIFRACL 137
>AB051553-1|BAB21857.1| 1123|Homo sapiens KIAA1766 protein protein.
Length = 1123
Score = 78.6 bits (185), Expect = 2e-13
Identities = 72/242 (29%), Positives = 101/242 (41%), Gaps = 26/242 (10%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+TE K+L HS L+ A+ SL+FP K+ PYIP+ P L EVL +P P++IGV S
Sbjct: 190 LTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHS 249
Query: 403 RFFDLYEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPAS 462
F DV DLD I + E I + LP+ L QT L + P
Sbjct: 250 VFKTDVHELLDVIIADLDGGTIKIPEC----IHLSSLPE---PLLHQTQSALSLILHPDL 302
Query: 463 PIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKA 522
+ + T+L + L+ +++ FLR A QGYRS L I
Sbjct: 303 EV----ADHAFPPPRTALSH-------SKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRI- 350
Query: 523 PTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDE 582
+P F FL R + F T ++ F F+ E Y + FDE
Sbjct: 351 ----HAEPVIHFHKTAFLGQRGLVENDFLTKVLSGMAFAGFVSERGPPY---RSCDLFDE 403
Query: 583 CI 584
+
Sbjct: 404 LV 405
Score = 44.0 bits (99), Expect = 0.004
Identities = 37/116 (31%), Positives = 52/116 (44%), Gaps = 10/116 (8%)
Query: 179 RYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAV 238
R+P D FP + LFC P G W + +P F VLT D +++ Y S +
Sbjct: 1 RFPQKDWDDTPFPQGIELFCQPGG-----WQLSRERKQPTFFVVVLTDID-SDRHYCSCL 54
Query: 239 TFYESYPYSELTETQMELLGWRANVSQ--NTHSVHVVKSVCLLSRWPFSDTFERWL 292
TFYE+ L T+ E + A VS V KS+ L+SR + + F L
Sbjct: 55 TFYEA--EINLQGTKKEEIEGEAKVSGLIQPAEVFAPKSLVLVSRLYYPEIFRACL 108
>AB020677-1|BAA74893.2| 1019|Homo sapiens KIAA0870 protein protein.
Length = 1019
Score = 68.9 bits (161), Expect = 1e-10
Identities = 50/224 (22%), Positives = 102/224 (45%), Gaps = 20/224 (8%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+TEQ+I+ S LT V+E + L+P +WQ P++P+ + + + AP +L+G
Sbjct: 32 LTEQRIVFFSSDWALLTLVTECFMAYLYPLQWQHPFVPILSDQMLDFVMAPTSFLMGCHL 91
Query: 403 RFFDLYEPPPD-VTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPA 461
F+ D + +++D +IT +S +N+ I +P + Q +++L
Sbjct: 92 DHFEEVSKEADGLVLINIDHGSITYSKSTDDNVDIPDVPLLAAQTFIQRVQSL------- 144
Query: 462 SPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITK 521
+HH + +T + +R +Q L +IQ+ L+ + + +++L
Sbjct: 145 -QLHHELHAAHLLSSTDLKEGRAHRRSWQQKLNCQIQQTTLQLLVSIFRDVKNHL----- 198
Query: 522 APTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQMFTRFIE 565
+F EFL++R +F+ ++ T MF F++
Sbjct: 199 ------NYEHRVFNSEEFLKTRAPGDHQFYKQVLDTYMFHSFLK 236
>BC063877-1|AAH63877.1| 426|Homo sapiens DENND1B protein protein.
Length = 426
Score = 67.3 bits (157), Expect = 4e-10
Identities = 55/174 (31%), Positives = 87/174 (50%), Gaps = 13/174 (7%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++I+I S + TLTA ++LL+P WQ YIP+ P L + AP+PYLIG+ S
Sbjct: 212 ERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSL 271
Query: 405 FDLYEPP--PDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG----SI 458
+ + DV +++DTN + S NN+ ++ + K KQ+ T G +
Sbjct: 272 IERVKNKSLEDVVMLNVDTNTLESPFSDLNNLPSDVVSALKNKLKKQSTATGDGVARAFL 331
Query: 459 RPASPIHHSSRN--RYN-GEATTSLDRDFQKRKK---EQALELKIQ-EAFLRFM 505
R + + S R+ RY GE T + F K + +Q LE I + F +F+
Sbjct: 332 RAQAALFGSYRDALRYKPGEPITFCEESFVKHRSSVMKQFLETAINLQLFKQFI 385
>AL365258-6|CAI14213.1| 426|Homo sapiens DENN/MADD domain
containing 1B protein.
Length = 426
Score = 67.3 bits (157), Expect = 4e-10
Identities = 55/174 (31%), Positives = 87/174 (50%), Gaps = 13/174 (7%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++I+I S + TLTA ++LL+P WQ YIP+ P L + AP+PYLIG+ S
Sbjct: 212 ERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSL 271
Query: 405 FDLYEPP--PDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG----SI 458
+ + DV +++DTN + S NN+ ++ + K KQ+ T G +
Sbjct: 272 IERVKNKSLEDVVMLNVDTNTLESPFSDLNNLPSDVVSALKNKLKKQSTATGDGVARAFL 331
Query: 459 RPASPIHHSSRN--RYN-GEATTSLDRDFQKRKK---EQALELKIQ-EAFLRFM 505
R + + S R+ RY GE T + F K + +Q LE I + F +F+
Sbjct: 332 RAQAALFGSYRDALRYKPGEPITFCEESFVKHRSSVMKQFLETAINLQLFKQFI 385
>AL365258-5|CAI14214.1| 406|Homo sapiens DENN/MADD domain
containing 1B protein.
Length = 406
Score = 67.3 bits (157), Expect = 4e-10
Identities = 55/174 (31%), Positives = 87/174 (50%), Gaps = 13/174 (7%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++I+I S + TLTA ++LL+P WQ YIP+ P L + AP+PYLIG+ S
Sbjct: 192 ERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSL 251
Query: 405 FDLYEPP--PDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG----SI 458
+ + DV +++DTN + S NN+ ++ + K KQ+ T G +
Sbjct: 252 IERVKNKSLEDVVMLNVDTNTLESPFSDLNNLPSDVVSALKNKLKKQSTATGDGVARAFL 311
Query: 459 RPASPIHHSSRN--RYN-GEATTSLDRDFQKRKK---EQALELKIQ-EAFLRFM 505
R + + S R+ RY GE T + F K + +Q LE I + F +F+
Sbjct: 312 RAQAALFGSYRDALRYKPGEPITFCEESFVKHRSSVMKQFLETAINLQLFKQFI 365
>AL139136-7|CAI15315.1| 406|Homo sapiens DENN/MADD domain
containing 1B protein.
Length = 406
Score = 67.3 bits (157), Expect = 4e-10
Identities = 55/174 (31%), Positives = 87/174 (50%), Gaps = 13/174 (7%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++I+I S + TLTA ++LL+P WQ YIP+ P L + AP+PYLIG+ S
Sbjct: 192 ERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSL 251
Query: 405 FDLYEPP--PDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG----SI 458
+ + DV +++DTN + S NN+ ++ + K KQ+ T G +
Sbjct: 252 IERVKNKSLEDVVMLNVDTNTLESPFSDLNNLPSDVVSALKNKLKKQSTATGDGVARAFL 311
Query: 459 RPASPIHHSSRN--RYN-GEATTSLDRDFQKRKK---EQALELKIQ-EAFLRFM 505
R + + S R+ RY GE T + F K + +Q LE I + F +F+
Sbjct: 312 RAQAALFGSYRDALRYKPGEPITFCEESFVKHRSSVMKQFLETAINLQLFKQFI 365
>AL139136-6|CAI15314.1| 426|Homo sapiens DENN/MADD domain
containing 1B protein.
Length = 426
Score = 67.3 bits (157), Expect = 4e-10
Identities = 55/174 (31%), Positives = 87/174 (50%), Gaps = 13/174 (7%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++I+I S + TLTA ++LL+P WQ YIP+ P L + AP+PYLIG+ S
Sbjct: 212 ERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSL 271
Query: 405 FDLYEPP--PDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG----SI 458
+ + DV +++DTN + S NN+ ++ + K KQ+ T G +
Sbjct: 272 IERVKNKSLEDVVMLNVDTNTLESPFSDLNNLPSDVVSALKNKLKKQSTATGDGVARAFL 331
Query: 459 RPASPIHHSSRN--RYN-GEATTSLDRDFQKRKK---EQALELKIQ-EAFLRFM 505
R + + S R+ RY GE T + F K + +Q LE I + F +F+
Sbjct: 332 RAQAALFGSYRDALRYKPGEPITFCEESFVKHRSSVMKQFLETAINLQLFKQFI 385
>BC087612-1|AAH87612.1| 1893|Homo sapiens SBF1 protein protein.
Length = 1893
Score = 65.3 bits (152), Expect = 2e-09
Identities = 64/243 (26%), Positives = 99/243 (40%), Gaps = 26/243 (10%)
Query: 342 AITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVD 401
A+TE K+L S L + +LLFP ++ Y+P+ P L EVL P P++IGV+
Sbjct: 230 ALTEHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVN 289
Query: 402 SRFFDLYEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPA 461
+ F + DV DLD +T+ E + I LP+ QT L + P
Sbjct: 290 AAFQAETQELLDVIVADLDGGTVTIPEC----VHIPPLPE---PLQSQTHSVLSMVLDPE 342
Query: 462 SPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITK 521
+ + + T++ Q + +++ FLR A LQGYR L +
Sbjct: 343 LELADLA---FPPPTTSTSSLKMQDK--------ELRAVFLRLFAQLLQGYRWCLHVVRI 391
Query: 522 APTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFD 581
P +P F FL R + F ++ F F+ E Y + FD
Sbjct: 392 HP-----EPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPY---RPTDLFD 443
Query: 582 ECI 584
E +
Sbjct: 444 ELV 446
Score = 35.9 bits (79), Expect = 1.2
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 176 VLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYG 235
+L R+P D FP + LFC P G +L P +P P F VLT + +E+ Y
Sbjct: 27 ILQRFPEKDWEDNPFPQGIELFCQPSG--WQLCPER--NP-PTFFVAVLTDIN-SERHYC 80
Query: 236 SAVTFYE-SYPYSELTETQ 253
+ +TF+E + P E T +
Sbjct: 81 ACLTFWEPAEPSQETTRVE 99
>BC022561-1|AAH22561.1| 396|Homo sapiens DENN/MADD domain
containing 1B protein.
Length = 396
Score = 65.3 bits (152), Expect = 2e-09
Identities = 40/117 (34%), Positives = 62/117 (52%), Gaps = 2/117 (1%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++I+I S + TLTA ++LL+P WQ YIP+ P L + AP+PYLIG+ S
Sbjct: 182 ERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSL 241
Query: 405 FDLYEPP--PDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIR 459
+ + DV +++DTN + S NN+ ++ + K KQ+ T G R
Sbjct: 242 IERVKNKSLEDVVMLNVDTNTLESPFSDLNNLPSDVVSALKNKLKKQSTATGDGVAR 298
>AL096767-2|CAI42962.1| 1867|Homo sapiens SET binding factor 1
protein.
Length = 1867
Score = 65.3 bits (152), Expect = 2e-09
Identities = 64/243 (26%), Positives = 99/243 (40%), Gaps = 26/243 (10%)
Query: 342 AITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVD 401
A+TE K+L S L + +LLFP ++ Y+P+ P L EVL P P++IGV+
Sbjct: 230 ALTEHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVN 289
Query: 402 SRFFDLYEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPA 461
+ F + DV DLD +T+ E + I LP+ QT L + P
Sbjct: 290 AAFQAETQELLDVIVADLDGGTVTIPEC----VHIPPLPE---PLQSQTHSVLSMVLDPE 342
Query: 462 SPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITK 521
+ + + T++ Q + +++ FLR A LQGYR L +
Sbjct: 343 LELADLA---FPPPTTSTSSLKMQDK--------ELRAVFLRLFAQLLQGYRWCLHVVRI 391
Query: 522 APTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFD 581
P +P F FL R + F ++ F F+ E Y + FD
Sbjct: 392 HP-----EPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPY---RPTDLFD 443
Query: 582 ECI 584
E +
Sbjct: 444 ELV 446
Score = 35.9 bits (79), Expect = 1.2
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 176 VLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYG 235
+L R+P D FP + LFC P G +L P +P P F VLT + +E+ Y
Sbjct: 27 ILQRFPEKDWEDNPFPQGIELFCQPSG--WQLCPER--NP-PTFFVAVLTDIN-SERHYC 80
Query: 236 SAVTFYE-SYPYSELTETQ 253
+ +TF+E + P E T +
Sbjct: 81 ACLTFWEPAEPSQETTRVE 99
>AB209682-1|BAD92919.1| 858|Homo sapiens SET binding factor 1
isoform a variant protein.
Length = 858
Score = 65.3 bits (152), Expect = 2e-09
Identities = 64/243 (26%), Positives = 99/243 (40%), Gaps = 26/243 (10%)
Query: 342 AITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVD 401
A+TE K+L S L + +LLFP ++ Y+P+ P L EVL P P++IGV+
Sbjct: 203 ALTEHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVN 262
Query: 402 SRFFDLYEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPA 461
+ F + DV DLD +T+ E + I LP+ QT L + P
Sbjct: 263 AAFQAETQELLDVIVADLDGGTVTIPEC----VHIPPLPE---PLQSQTHSVLSMVLDPE 315
Query: 462 SPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITK 521
+ + + T++ Q + +++ FLR A LQGYR L +
Sbjct: 316 LELADLA---FPPPTTSTSSLKMQDK--------ELRAVFLRLFAQLLQGYRWCLHVVRI 364
Query: 522 APTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFD 581
P +P F FL R + F ++ F F+ E Y + FD
Sbjct: 365 HP-----EPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPY---RPTDLFD 416
Query: 582 ECI 584
E +
Sbjct: 417 ELV 419
Score = 35.5 bits (78), Expect = 1.6
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 6/77 (7%)
Query: 179 RYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAV 238
R+P D FP + LFC P G +L P +P P F VLT + +E+ Y + +
Sbjct: 2 RFPEKDWEDNPFPQGIELFCQPSG--WQLCPER--NP-PTFFVAVLTDIN-SERHYCACL 55
Query: 239 TFYESYPYSELTETQME 255
TF+E S+ T++E
Sbjct: 56 TFWEPAEPSQQETTRVE 72
>U15780-1|AAC50926.1| 717|Homo sapiens p82 protein.
Length = 717
Score = 63.7 bits (148), Expect = 5e-09
Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 37/247 (14%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIG-VD 401
+ E++++ + + TL++ S AV +LL+PF WQ +IP+ P + +++ P P+L+G +
Sbjct: 474 LLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLS 533
Query: 402 SRFFDLYE-PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRP 460
S L E P + V+L ++ ++ + LLP++ AL+Q LE
Sbjct: 534 SSLPKLKELPVEEALMVNLGSDRFI----RQMDDEDTLLPRKLQAALEQALE-------- 581
Query: 461 ASPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPIT 520
R N S D D + L + E F+RF T+ Y +L
Sbjct: 582 ----------RKN--ELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSE 629
Query: 521 KAPTVGTTDPDALFQMNEFLRS-REKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTF 579
K + FQ F +S K+ +RF + M +QMF FI++ +GL
Sbjct: 630 KG--------ERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGL-- 679
Query: 580 FDECIEK 586
F++ +E+
Sbjct: 680 FEQRVEQ 686
>U15779-1|AAB97097.1| 609|Homo sapiens p70 protein.
Length = 609
Score = 63.7 bits (148), Expect = 5e-09
Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 37/247 (14%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIG-VD 401
+ E++++ + + TL++ S AV +LL+PF WQ +IP+ P + +++ P P+L+G +
Sbjct: 366 LLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLS 425
Query: 402 SRFFDLYE-PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRP 460
S L E P + V+L ++ ++ + LLP++ AL+Q LE
Sbjct: 426 SSLPKLKELPVEEALMVNLGSDRFI----RQMDDEDTLLPRKLQAALEQALE-------- 473
Query: 461 ASPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPIT 520
R N S D D + L + E F+RF T+ Y +L
Sbjct: 474 ----------RKN--ELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSE 521
Query: 521 KAPTVGTTDPDALFQMNEFLRS-REKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTF 579
K + FQ F +S K+ +RF + M +QMF FI++ +GL
Sbjct: 522 KG--------ERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGL-- 571
Query: 580 FDECIEK 586
F++ +E+
Sbjct: 572 FEQRVEQ 578
>U15131-1|AAC50925.1| 1137|Homo sapiens p126 protein.
Length = 1137
Score = 63.7 bits (148), Expect = 5e-09
Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 37/247 (14%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIG-VD 401
+ E++++ + + TL++ S AV +LL+PF WQ +IP+ P + +++ P P+L+G +
Sbjct: 894 LLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLS 953
Query: 402 SRFFDLYE-PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRP 460
S L E P + V+L ++ ++ + LLP++ AL+Q LE
Sbjct: 954 SSLPKLKELPVEEALMVNLGSDRFI----RQMDDEDTLLPRKLQAALEQALE-------- 1001
Query: 461 ASPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPIT 520
R N S D D + L + E F+RF T+ Y +L
Sbjct: 1002 ----------RKN--ELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSE 1049
Query: 521 KAPTVGTTDPDALFQMNEFLRS-REKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTF 579
K + FQ F +S K+ +RF + M +QMF FI++ +GL
Sbjct: 1050 KG--------ERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGL-- 1099
Query: 580 FDECIEK 586
F++ +E+
Sbjct: 1100 FEQRVEQ 1106
>S45936-1|AAB23647.1| 645|Homo sapiens HTS1 protein.
Length = 645
Score = 63.7 bits (148), Expect = 5e-09
Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 37/247 (14%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIG-VD 401
+ E++++ + + TL++ S AV +LL+PF WQ +IP+ P + +++ P P+L+G +
Sbjct: 402 LLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLS 461
Query: 402 SRFFDLYE-PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRP 460
S L E P + V+L ++ ++ + LLP++ AL+Q LE
Sbjct: 462 SSLPKLKELPVEEALMVNLGSDRFI----RQMDDEDTLLPRKLQAALEQALE-------- 509
Query: 461 ASPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPIT 520
R N S D D + L + E F+RF T+ Y +L
Sbjct: 510 ----------RKN--ELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSE 557
Query: 521 KAPTVGTTDPDALFQMNEFLRS-REKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTF 579
K + FQ F +S K+ +RF + M +QMF FI++ +GL
Sbjct: 558 KG--------ERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGL-- 607
Query: 580 FDECIEK 586
F++ +E+
Sbjct: 608 FEQRVEQ 614
>BC036655-1|AAH36655.1| 1137|Homo sapiens suppression of
tumorigenicity 5 protein.
Length = 1137
Score = 63.7 bits (148), Expect = 5e-09
Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 37/247 (14%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIG-VD 401
+ E++++ + + TL++ S AV +LL+PF WQ +IP+ P + +++ P P+L+G +
Sbjct: 894 LLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLS 953
Query: 402 SRFFDLYE-PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRP 460
S L E P + V+L ++ ++ + LLP++ AL+Q LE
Sbjct: 954 SSLPKLKELPVEEALMVNLGSDRFI----RQMDDEDTLLPRKLQAALEQALE-------- 1001
Query: 461 ASPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPIT 520
R N S D D + L + E F+RF T+ Y +L
Sbjct: 1002 ----------RKN--ELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSE 1049
Query: 521 KAPTVGTTDPDALFQMNEFLRS-REKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTF 579
K + FQ F +S K+ +RF + M +QMF FI++ +GL
Sbjct: 1050 KG--------ERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGL-- 1099
Query: 580 FDECIEK 586
F++ +E+
Sbjct: 1100 FEQRVEQ 1106
>AJ400879-1|CAC35387.1| 1137|Homo sapiens suppression of
tumorigenicity 5 protein.
Length = 1137
Score = 63.7 bits (148), Expect = 5e-09
Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 37/247 (14%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIG-VD 401
+ E++++ + + TL++ S AV +LL+PF WQ +IP+ P + +++ P P+L+G +
Sbjct: 894 LLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLS 953
Query: 402 SRFFDLYE-PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRP 460
S L E P + V+L ++ ++ + LLP++ AL+Q LE
Sbjct: 954 SSLPKLKELPVEEALMVNLGSDRFI----RQMDDEDTLLPRKLQAALEQALE-------- 1001
Query: 461 ASPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPIT 520
R N S D D + L + E F+RF T+ Y +L
Sbjct: 1002 ----------RKN--ELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSE 1049
Query: 521 KAPTVGTTDPDALFQMNEFLRS-REKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGLTF 579
K + FQ F +S K+ +RF + M +QMF FI++ +GL
Sbjct: 1050 KG--------ERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGL-- 1099
Query: 580 FDECIEK 586
F++ +E+
Sbjct: 1100 FEQRVEQ 1106
>BC071596-1|AAH71596.1| 1287|Homo sapiens RAB6 interacting protein 1
protein.
Length = 1287
Score = 63.3 bits (147), Expect = 7e-09
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 5/92 (5%)
Query: 342 AITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVD 401
A+ E +IL++S L V+E +++L+FPF+WQ Y+P+ P L L AP+PYL+G+
Sbjct: 305 ALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLH 364
Query: 402 SRFFD----LYEPPPDVTC-VDLDTNNITVCE 428
S D L P C VD+D + I + E
Sbjct: 365 SNGLDDRSKLELPQEANLCFVDIDNHFIELPE 396
>AB029014-1|BAA83043.1| 1359|Homo sapiens KIAA1091 protein protein.
Length = 1359
Score = 63.3 bits (147), Expect = 7e-09
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 5/92 (5%)
Query: 342 AITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVD 401
A+ E +IL++S L V+E +++L+FPF+WQ Y+P+ P L L AP+PYL+G+
Sbjct: 377 ALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLH 436
Query: 402 SRFFD----LYEPPPDVTC-VDLDTNNITVCE 428
S D L P C VD+D + I + E
Sbjct: 437 SNGLDDRSKLELPQEANLCFVDIDNHFIELPE 468
>BC068580-1|AAH68580.1| 738|Homo sapiens MGC24039 protein protein.
Length = 738
Score = 62.5 bits (145), Expect = 1e-08
Identities = 26/61 (42%), Positives = 41/61 (67%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+ E +IL++S L V+E +++LLFPF+WQ Y+P+ P L L AP+PYL+G+ S
Sbjct: 313 LLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQS 372
Query: 403 R 403
+
Sbjct: 373 K 373
>BC020855-1|AAH20855.1| 507|Homo sapiens MGC24039 protein protein.
Length = 507
Score = 62.5 bits (145), Expect = 1e-08
Identities = 26/61 (42%), Positives = 41/61 (67%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+ E +IL++S L V+E +++LLFPF+WQ Y+P+ P L L AP+PYL+G+ S
Sbjct: 213 LLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQS 272
Query: 403 R 403
+
Sbjct: 273 K 273
>AK125323-1|BAC86129.1| 1309|Homo sapiens protein ( Homo sapiens
cDNA FLJ43333 fis, clone NT2RI3006376. ).
Length = 1309
Score = 62.5 bits (145), Expect = 1e-08
Identities = 26/61 (42%), Positives = 41/61 (67%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+ E +IL++S L V+E +++LLFPF+WQ Y+P+ P L L AP+PYL+G+ S
Sbjct: 326 LLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQS 385
Query: 403 R 403
+
Sbjct: 386 K 386
>AL831839-1|CAD38548.1| 190|Homo sapiens hypothetical protein
protein.
Length = 190
Score = 62.1 bits (144), Expect = 2e-08
Identities = 34/103 (33%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++I+I S + TLTA ++LL+P WQ YIP+ P L + AP+PYLIG+ S
Sbjct: 87 ERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSL 146
Query: 405 FDLYEPP--PDVTCVDLDTNNITVCESQRNNISIKLLPKRQVK 445
+ + DV +++DTN + S NN+ ++ + ++
Sbjct: 147 IERVKNKSLEDVVMLNVDTNTLESPFSDLNNLPSDVVSMKAIQ 189
>AL133382-2|CAM27633.1| 928|Homo sapiens DENN/MADD domain
containing 2C protein.
Length = 928
Score = 60.1 bits (139), Expect = 6e-08
Identities = 64/238 (26%), Positives = 106/238 (44%), Gaps = 38/238 (15%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+ E++++ + TL+ AV + L+PF WQ YIP+ P + +++ +P P+LIG+ S
Sbjct: 689 LLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILS 748
Query: 403 RFFDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRP 460
+ P +V VDL + S + I LP + AL Q LE
Sbjct: 749 CSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEI----LPPKLQAALMQILE-------- 796
Query: 461 ASPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPIT 520
RN E T +++F ++ L + EAF+RF L G+ S + +T
Sbjct: 797 -------ERN----EILTQ-EQNF---SQDVTLNSLVSEAFVRFFV-ELVGHYSLNMTVT 840
Query: 521 KAPTVGTTDPDALFQMNEFLRSR-EKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGL 577
+ + +FQ F +S ++ + F L M TQMF FI++ +GL
Sbjct: 841 ER-------GERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDRELRKSGVKGL 891
>AL133382-1|CAI19301.1| 871|Homo sapiens DENN/MADD domain
containing 2C protein.
Length = 871
Score = 60.1 bits (139), Expect = 6e-08
Identities = 64/238 (26%), Positives = 106/238 (44%), Gaps = 38/238 (15%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+ E++++ + TL+ AV + L+PF WQ YIP+ P + +++ +P P+LIG+ S
Sbjct: 632 LLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILS 691
Query: 403 RFFDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRP 460
+ P +V VDL + S + I LP + AL Q LE
Sbjct: 692 CSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEI----LPPKLQAALMQILE-------- 739
Query: 461 ASPIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPIT 520
RN E T +++F ++ L + EAF+RF L G+ S + +T
Sbjct: 740 -------ERN----EILTQ-EQNF---SQDVTLNSLVSEAFVRFFV-ELVGHYSLNMTVT 783
Query: 521 KAPTVGTTDPDALFQMNEFLRSR-EKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGL 577
+ + +FQ F +S ++ + F L M TQMF FI++ +GL
Sbjct: 784 ER-------GERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDRELRKSGVKGL 834
>U77352-1|AAB57735.1| 1588|Homo sapiens MAP kinase-activating death
domain protein protein.
Length = 1588
Score = 59.7 bits (138), Expect = 8e-08
Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 32/246 (13%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLA---EVLHAPLPYLIG 399
+ E K+++ S + L+ A ++++P ++ P IPL P +A ++L AP PY+IG
Sbjct: 317 LLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIG 376
Query: 400 VDSRFFDL---YEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG 456
V + FF ++ P DV VDLD+N + + N + +LP+ + LK+ L+
Sbjct: 377 VPASFFLYKLDFKMPDDVWLVDLDSNRVI---APTNAEVLPILPEPESLELKKHLKQALA 433
Query: 457 SIR-PASPIHHSSRNRYNGEATTSLDR---DFQKRKKEQ-----------ALELKIQEAF 501
S+ PI + + E L R D Q + ++++ + A
Sbjct: 434 SMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAM 493
Query: 502 LRFM--ACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQM 559
+RF A LQG++ + + P P FQ FL SR + Q F + RTQ
Sbjct: 494 VRFFNSANVLQGFQMHTRTLRLFPR-----PVVAFQAGSFLASRPR-QTPFAEKLARTQA 547
Query: 560 FTRFIE 565
F E
Sbjct: 548 VEYFGE 553
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 170 ISYKPDVLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADA 229
++ P++L RYP+ D PP V FC P G L + + F LT D
Sbjct: 28 VAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGC-LSVRQRRMSLRDDTSFVFTLTDKDT 86
Query: 230 TEKVYGSAVTFYESY 244
YG V FY S+
Sbjct: 87 GVTRYGICVNFYRSF 101
>U44953-1|AAD12154.1| 1587|Homo sapiens DENN protein.
Length = 1587
Score = 59.7 bits (138), Expect = 8e-08
Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 32/246 (13%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLA---EVLHAPLPYLIG 399
+ E K+++ S + L+ A ++++P ++ P IPL P +A ++L AP PY+IG
Sbjct: 317 LLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIG 376
Query: 400 VDSRFFDL---YEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG 456
V + FF ++ P DV VDLD+N + + N + +LP+ + LK+ L+
Sbjct: 377 VPASFFLYKLDFKMPDDVWLVDLDSNRVI---APTNAEVLPILPEPESLELKKHLKQALA 433
Query: 457 SIR-PASPIHHSSRNRYNGEATTSLDR---DFQKRKKEQ-----------ALELKIQEAF 501
S+ PI + + E L R D Q + ++++ + A
Sbjct: 434 SMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAM 493
Query: 502 LRFM--ACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQM 559
+RF A LQG++ + + P P FQ FL SR + Q F + RTQ
Sbjct: 494 VRFFNSANVLQGFQMHTRTLRLFPR-----PVVAFQAGSFLASRPR-QTPFAEKLARTQA 547
Query: 560 FTRFIE 565
F E
Sbjct: 548 VEYFGE 553
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 170 ISYKPDVLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADA 229
++ P++L RYP+ D PP V FC P G L + + F LT D
Sbjct: 28 VAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGC-LSVRQRRMSLRDDTSFVFTLTDKDT 86
Query: 230 TEKVYGSAVTFYESY 244
YG V FY S+
Sbjct: 87 GVTRYGICVNFYRSF 101
>BC040484-1|AAH40484.1| 1544|Homo sapiens MADD protein protein.
Length = 1544
Score = 59.7 bits (138), Expect = 8e-08
Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 32/246 (13%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLA---EVLHAPLPYLIG 399
+ E K+++ S + L+ A ++++P ++ P IPL P +A ++L AP PY+IG
Sbjct: 317 LLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIG 376
Query: 400 VDSRFFDL---YEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG 456
V + FF ++ P DV VDLD+N + + N + +LP+ + LK+ L+
Sbjct: 377 VPASFFLYKLDFKMPDDVWLVDLDSNRVI---APTNAEVLPILPEPESLELKKHLKQALA 433
Query: 457 SIR-PASPIHHSSRNRYNGEATTSLDR---DFQKRKKEQ-----------ALELKIQEAF 501
S+ PI + + E L R D Q + ++++ + A
Sbjct: 434 SMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAM 493
Query: 502 LRFM--ACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQM 559
+RF A LQG++ + + P P FQ FL SR + Q F + RTQ
Sbjct: 494 VRFFNSANVLQGFQMHTRTLRLFPR-----PVVAFQAGSFLASRPR-QTPFAEKLARTQA 547
Query: 560 FTRFIE 565
F E
Sbjct: 548 VEYFGE 553
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 170 ISYKPDVLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADA 229
++ P++L RYP+ D PP V FC P G L + + F LT D
Sbjct: 28 VAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGC-LSVRQRRMSLRDDTSFVFTLTDKDT 86
Query: 230 TEKVYGSAVTFYESY 244
YG V FY S+
Sbjct: 87 GVTRYGICVNFYRSF 101
>AF440434-1|AAL35261.1| 1479|Homo sapiens insulinoma-glucagonoma
protein 20 splice variant 4 protein.
Length = 1479
Score = 59.7 bits (138), Expect = 8e-08
Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 32/246 (13%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLA---EVLHAPLPYLIG 399
+ E K+++ S + L+ A ++++P ++ P IPL P +A ++L AP PY+IG
Sbjct: 317 LLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIG 376
Query: 400 VDSRFFDL---YEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG 456
V + FF ++ P DV VDLD+N + + N + +LP+ + LK+ L+
Sbjct: 377 VPASFFLYKLDFKMPDDVWLVDLDSNRVI---APTNAEVLPILPEPESLELKKHLKQALA 433
Query: 457 SIR-PASPIHHSSRNRYNGEATTSLDR---DFQKRKKEQ-----------ALELKIQEAF 501
S+ PI + + E L R D Q + ++++ + A
Sbjct: 434 SMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDADSVDVATRVAM 493
Query: 502 LRFM--ACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQM 559
+RF A LQG++ + + P P FQ FL SR + Q F + RTQ
Sbjct: 494 VRFFNSANVLQGFQMHTRTLRLFPR-----PVVAFQAGSFLASRPR-QTPFAEKLARTQA 547
Query: 560 FTRFIE 565
F E
Sbjct: 548 VEYFGE 553
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 170 ISYKPDVLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADA 229
++ P++L RYP+ D PP V FC P G L + + F LT D
Sbjct: 28 VAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGC-LSVRQRRMSLRDDTSFVFTLTDKDT 86
Query: 230 TEKVYGSAVTFYESY 244
YG V FY S+
Sbjct: 87 GVTRYGICVNFYRSF 101
>AF440103-1|AAL40268.1| 1545|Homo sapiens insulinoma-glucagonoma
protein 20 splice variant 3 protein.
Length = 1545
Score = 59.7 bits (138), Expect = 8e-08
Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 32/246 (13%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLA---EVLHAPLPYLIG 399
+ E K+++ S + L+ A ++++P ++ P IPL P +A ++L AP PY+IG
Sbjct: 317 LLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIG 376
Query: 400 VDSRFFDL---YEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG 456
V + FF ++ P DV VDLD+N + + N + +LP+ + LK+ L+
Sbjct: 377 VPASFFLYKLDFKMPDDVWLVDLDSNRVI---APTNAEVLPILPEPESLELKKHLKQALA 433
Query: 457 SIR-PASPIHHSSRNRYNGEATTSLDR---DFQKRKKEQ-----------ALELKIQEAF 501
S+ PI + + E L R D Q + ++++ + A
Sbjct: 434 SMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDADSVDVATRVAM 493
Query: 502 LRFM--ACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQM 559
+RF A LQG++ + + P P FQ FL SR + Q F + RTQ
Sbjct: 494 VRFFNSANVLQGFQMHTRTLRLFPR-----PVVAFQAGSFLASRPR-QTPFAEKLARTQA 547
Query: 560 FTRFIE 565
F E
Sbjct: 548 VEYFGE 553
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 170 ISYKPDVLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADA 229
++ P++L RYP+ D PP V FC P G L + + F LT D
Sbjct: 28 VAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGC-LSVRQRRMSLRDDTSFVFTLTDKDT 86
Query: 230 TEKVYGSAVTFYESY 244
YG V FY S+
Sbjct: 87 GVTRYGICVNFYRSF 101
>AF440102-1|AAL40267.1| 1565|Homo sapiens insulinoma-glucagonoma
protein 20 splice variant 2 protein.
Length = 1565
Score = 59.7 bits (138), Expect = 8e-08
Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 32/246 (13%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLA---EVLHAPLPYLIG 399
+ E K+++ S + L+ A ++++P ++ P IPL P +A ++L AP PY+IG
Sbjct: 317 LLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIG 376
Query: 400 VDSRFFDL---YEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG 456
V + FF ++ P DV VDLD+N + + N + +LP+ + LK+ L+
Sbjct: 377 VPASFFLYKLDFKMPDDVWLVDLDSNRVI---APTNAEVLPILPEPESLELKKHLKQALA 433
Query: 457 SIR-PASPIHHSSRNRYNGEATTSLDR---DFQKRKKEQ-----------ALELKIQEAF 501
S+ PI + + E L R D Q + ++++ + A
Sbjct: 434 SMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDADSVDVATRVAM 493
Query: 502 LRFM--ACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQM 559
+RF A LQG++ + + P P FQ FL SR + Q F + RTQ
Sbjct: 494 VRFFNSANVLQGFQMHTRTLRLFPR-----PVVAFQAGSFLASRPR-QTPFAEKLARTQA 547
Query: 560 FTRFIE 565
F E
Sbjct: 548 VEYFGE 553
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 170 ISYKPDVLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADA 229
++ P++L RYP+ D PP V FC P G L + + F LT D
Sbjct: 28 VAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGC-LSVRQRRMSLRDDTSFVFTLTDKDT 86
Query: 230 TEKVYGSAVTFYESY 244
YG V FY S+
Sbjct: 87 GVTRYGICVNFYRSF 101
>AF440101-1|AAL40266.1| 1608|Homo sapiens insulinoma-glucagonoma
protein 20 pro-apoptotic splice variant protein.
Length = 1608
Score = 59.7 bits (138), Expect = 8e-08
Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 32/246 (13%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLA---EVLHAPLPYLIG 399
+ E K+++ S + L+ A ++++P ++ P IPL P +A ++L AP PY+IG
Sbjct: 317 LLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIG 376
Query: 400 VDSRFFDL---YEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG 456
V + FF ++ P DV VDLD+N + + N + +LP+ + LK+ L+
Sbjct: 377 VPASFFLYKLDFKMPDDVWLVDLDSNRVI---APTNAEVLPILPEPESLELKKHLKQALA 433
Query: 457 SIR-PASPIHHSSRNRYNGEATTSLDR---DFQKRKKEQ-----------ALELKIQEAF 501
S+ PI + + E L R D Q + ++++ + A
Sbjct: 434 SMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDADSVDVATRVAM 493
Query: 502 LRFM--ACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQM 559
+RF A LQG++ + + P P FQ FL SR + Q F + RTQ
Sbjct: 494 VRFFNSANVLQGFQMHTRTLRLFPR-----PVVAFQAGSFLASRPR-QTPFAEKLARTQA 547
Query: 560 FTRFIE 565
F E
Sbjct: 548 VEYFGE 553
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 170 ISYKPDVLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADA 229
++ P++L RYP+ D PP V FC P G L + + F LT D
Sbjct: 28 VAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGC-LSVRQRRMSLRDDTSFVFTLTDKDT 86
Query: 230 TEKVYGSAVTFYESY 244
YG V FY S+
Sbjct: 87 GVTRYGICVNFYRSF 101
>AF440100-1|AAL40265.1| 1647|Homo sapiens insulinoma-glucagonoma
protein 20 protein.
Length = 1647
Score = 59.7 bits (138), Expect = 8e-08
Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 32/246 (13%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLA---EVLHAPLPYLIG 399
+ E K+++ S + L+ A ++++P ++ P IPL P +A ++L AP PY+IG
Sbjct: 317 LLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIG 376
Query: 400 VDSRFFDL---YEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG 456
V + FF ++ P DV VDLD+N + + N + +LP+ + LK+ L+
Sbjct: 377 VPASFFLYKLDFKMPDDVWLVDLDSNRVI---APTNAEVLPILPEPESLELKKHLKQALA 433
Query: 457 SIR-PASPIHHSSRNRYNGEATTSLDR---DFQKRKKEQ-----------ALELKIQEAF 501
S+ PI + + E L R D Q + ++++ + A
Sbjct: 434 SMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDADSVDVATRVAM 493
Query: 502 LRFM--ACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQM 559
+RF A LQG++ + + P P FQ FL SR + Q F + RTQ
Sbjct: 494 VRFFNSANVLQGFQMHTRTLRLFPR-----PVVAFQAGSFLASRPR-QTPFAEKLARTQA 547
Query: 560 FTRFIE 565
F E
Sbjct: 548 VEYFGE 553
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 170 ISYKPDVLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADA 229
++ P++L RYP+ D PP V FC P G L + + F LT D
Sbjct: 28 VAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGC-LSVRQRRMSLRDDTSFVFTLTDKDT 86
Query: 230 TEKVYGSAVTFYESY 244
YG V FY S+
Sbjct: 87 GVTRYGICVNFYRSF 101
>AB002356-1|BAA20814.2| 1584|Homo sapiens KIAA0358 protein.
Length = 1584
Score = 59.7 bits (138), Expect = 8e-08
Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 32/246 (13%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLA---EVLHAPLPYLIG 399
+ E K+++ S + L+ A ++++P ++ P IPL P +A ++L AP PY+IG
Sbjct: 320 LLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIG 379
Query: 400 VDSRFFDL---YEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYG 456
V + FF ++ P DV VDLD+N + + N + +LP+ + LK+ L+
Sbjct: 380 VPASFFLYKLDFKMPDDVWLVDLDSNRVI---APTNAEVLPILPEPESLELKKHLKQALA 436
Query: 457 SIR-PASPIHHSSRNRYNGEATTSLDR---DFQKRKKEQ-----------ALELKIQEAF 501
S+ PI + + E L R D Q + ++++ + A
Sbjct: 437 SMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAM 496
Query: 502 LRFM--ACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSREKTQQRFFTLMMRTQM 559
+RF A LQG++ + + P P FQ FL SR + Q F + RTQ
Sbjct: 497 VRFFNSANVLQGFQMHTRTLRLFPR-----PVVAFQAGSFLASRPR-QTPFAEKLARTQA 550
Query: 560 FTRFIE 565
F E
Sbjct: 551 VEYFGE 556
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 170 ISYKPDVLFRYPVTDRRSLAFPPSVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADA 229
++ P++L RYP+ D PP V FC P G L + + F LT D
Sbjct: 31 VAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGC-LSVRQRRMSLRDDTSFVFTLTDKDT 89
Query: 230 TEKVYGSAVTFYESY 244
YG V FY S+
Sbjct: 90 GVTRYGICVNFYRSF 104
>BC132875-1|AAI32876.1| 1009|Homo sapiens DENN/MADD domain
containing 2A protein.
Length = 1009
Score = 58.8 bits (136), Expect = 1e-07
Identities = 64/252 (25%), Positives = 106/252 (42%), Gaps = 29/252 (11%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+ E++++ + + L+ A+ +L++PF WQ YIP+ P + +++ +P P+LIG+ S
Sbjct: 763 LLERRVIFIADKLSILSKCCHAMVALIYPFAWQHTYIPVLPPAMVDIVCSPTPFLIGLLS 822
Query: 403 RFFDLYEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPAS 462
L P + +D N + SI LP++ AL+ LE
Sbjct: 823 SSLPLLRELPLEEVLVVDLVNSRFLRQMDDEDSI--LPRKLQVALEHILE---------- 870
Query: 463 PIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKA 522
RN E D + + L + EAF+RF + Y +L
Sbjct: 871 -----QRNELACEQDEG-PLDGRHGPESSPLNEVVSEAFVRFFVEIVGHYSLFL------ 918
Query: 523 PTVGTTDPDALFQMNEFLRS-REKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGL--TF 579
T G + L Q F ++ K+ + F + M TQMF FI+E +GL
Sbjct: 919 -TSGEREERTL-QREAFRKAVSSKSLRHFLEVFMETQMFRGFIQERELRRQDAKGLFEVR 976
Query: 580 FDECIEKIASGE 591
E +E + SGE
Sbjct: 977 AQEYLETLPSGE 988
>BC049193-1|AAH49193.1| 638|Homo sapiens DENND2A protein protein.
Length = 638
Score = 58.8 bits (136), Expect = 1e-07
Identities = 64/252 (25%), Positives = 106/252 (42%), Gaps = 29/252 (11%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+ E++++ + + L+ A+ +L++PF WQ YIP+ P + +++ +P P+LIG+ S
Sbjct: 392 LLERRVIFIADKLSILSKCCHAMVALIYPFAWQHTYIPVLPPAMVDIVCSPTPFLIGLLS 451
Query: 403 RFFDLYEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPAS 462
L P + +D N + SI LP++ AL+ LE
Sbjct: 452 SSLPLLRELPLEEVLVVDLVNSRFLRQMDDEDSI--LPRKLQVALEHILE---------- 499
Query: 463 PIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKA 522
RN E D + + L + EAF+RF + Y +L
Sbjct: 500 -----QRNELACEQDEG-PLDGRHGPESSPLNEVVSEAFVRFFVEIVGHYSLFL------ 547
Query: 523 PTVGTTDPDALFQMNEFLRS-REKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGL--TF 579
T G + L Q F ++ K+ + F + M TQMF FI+E +GL
Sbjct: 548 -TSGEREERTL-QREAFRKAVSSKSLRHFLEVFMETQMFRGFIQERELRRQDAKGLFEVR 605
Query: 580 FDECIEKIASGE 591
E +E + SGE
Sbjct: 606 AQEYLETLPSGE 617
>AB033103-1|BAA86591.2| 1039|Homo sapiens KIAA1277 protein protein.
Length = 1039
Score = 57.2 bits (132), Expect = 4e-07
Identities = 63/252 (25%), Positives = 105/252 (41%), Gaps = 29/252 (11%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+ E++++ + + L+ A+ +L++PF WQ YIP+ P + +++ +P P+LIG+ S
Sbjct: 793 LLERRVIFIADKLSILSKCCHAMVALIYPFAWQHTYIPVLPPAMVDIVCSPTPFLIGLLS 852
Query: 403 RFFDLYEPPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLETLYGSIRPAS 462
L P + +D N + SI LP++ L+ LE
Sbjct: 853 SSLPLLRELPLEEVLVVDLVNSRFLRQMDDEDSI--LPRKLQVVLEHILE---------- 900
Query: 463 PIHHSSRNRYNGEATTSLDRDFQKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKA 522
RN E D + + L + EAF+RF + Y +L
Sbjct: 901 -----QRNELACEQDEG-PLDGRHGPESSPLNEVVSEAFVRFFVEIVGHYSLFL------ 948
Query: 523 PTVGTTDPDALFQMNEFLRS-REKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGL--TF 579
T G + L Q F ++ K+ + F + M TQMF FI+E +GL
Sbjct: 949 -TSGEREERTL-QREAFRKAVSSKSLRHFLEVFMETQMFRGFIQERELRRQDAKGLFEVR 1006
Query: 580 FDECIEKIASGE 591
E +E + SGE
Sbjct: 1007 AQEYLETLPSGE 1018
>BC004557-1|AAH04557.1| 471|Homo sapiens DENN/MADD domain
containing 2D protein.
Length = 471
Score = 56.8 bits (131), Expect = 6e-07
Identities = 53/222 (23%), Positives = 87/222 (39%), Gaps = 17/222 (7%)
Query: 193 SVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTET 252
++PLFC P G W + P+ FS FVLT D + K+ G + P L +
Sbjct: 99 AIPLFCFPDGNE---WASLTEYPRETFS-FVLTNVDGSRKI-GYCRRLLPAGPGPRLPKV 153
Query: 253 Q--MELLGWRANVSQNTHSVHVVKSVCLLSRWPFSDTFE--------RWLLYILLSPSNP 302
+ +G S+ V + + +PF + + P +
Sbjct: 154 YCIISCIGCFGLFSKILDEVEKRHQISMAVIYPFMQGLREAAFPAPGKTVTLKSFIPDSG 213
Query: 303 SDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRPDTLTAVS 362
++ + +TR D L F A+ E+KI+ + TL+
Sbjct: 214 TEFISLTRPLDSHLEH--VDFSSLLHCLSFEQILQIFASAVLERKIIFLAEGLSTLSQCI 271
Query: 363 EAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
A ++LL+PF W YIP+ P L + P P+++GV RF
Sbjct: 272 HAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRF 313
>AL355816-4|CAI19369.1| 468|Homo sapiens DENN/MADD domain
containing 2D protein.
Length = 468
Score = 56.8 bits (131), Expect = 6e-07
Identities = 53/222 (23%), Positives = 87/222 (39%), Gaps = 17/222 (7%)
Query: 193 SVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTET 252
++PLFC P G W + P+ FS FVLT D + K+ G + P L +
Sbjct: 96 AIPLFCFPDGNE---WASLTEYPRETFS-FVLTNVDGSRKI-GYCRRLLPAGPGPRLPKV 150
Query: 253 Q--MELLGWRANVSQNTHSVHVVKSVCLLSRWPFSDTFE--------RWLLYILLSPSNP 302
+ +G S+ V + + +PF + + P +
Sbjct: 151 YCIISCIGCFGLFSKILDEVEKRHQISMAVIYPFMQGLREAAFPAPGKTVTLKSFIPDSG 210
Query: 303 SDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRPDTLTAVS 362
++ + +TR D L F A+ E+KI+ + TL+
Sbjct: 211 TEFISLTRPLDSHLEH--VDFSSLLHCLSFEQILQIFASAVLERKIIFLAEGLSTLSQCI 268
Query: 363 EAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
A ++LL+PF W YIP+ P L + P P+++GV RF
Sbjct: 269 HAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRF 310
>AL355816-3|CAI19368.1| 471|Homo sapiens DENN/MADD domain
containing 2D protein.
Length = 471
Score = 56.8 bits (131), Expect = 6e-07
Identities = 53/222 (23%), Positives = 87/222 (39%), Gaps = 17/222 (7%)
Query: 193 SVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTET 252
++PLFC P G W + P+ FS FVLT D + K+ G + P L +
Sbjct: 99 AIPLFCFPDGNE---WASLTEYPRETFS-FVLTNVDGSRKI-GYCRRLLPAGPGPRLPKV 153
Query: 253 Q--MELLGWRANVSQNTHSVHVVKSVCLLSRWPFSDTFE--------RWLLYILLSPSNP 302
+ +G S+ V + + +PF + + P +
Sbjct: 154 YCIISCIGCFGLFSKILDEVEKRHQISMAVIYPFMQGLREAAFPAPGKTVTLKSFIPDSG 213
Query: 303 SDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRPDTLTAVS 362
++ + +TR D L F A+ E+KI+ + TL+
Sbjct: 214 TEFISLTRPLDSHLEH--VDFSSLLHCLSFEQILQIFASAVLERKIIFLAEGLSTLSQCI 271
Query: 363 EAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
A ++LL+PF W YIP+ P L + P P+++GV RF
Sbjct: 272 HAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRF 313
>U93181-1|AAC39675.1| 1697|Homo sapiens nuclear dual-specificity
phosphatase protein.
Length = 1697
Score = 56.4 bits (130), Expect = 8e-07
Identities = 57/218 (26%), Positives = 89/218 (40%), Gaps = 26/218 (11%)
Query: 367 SLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPPDVTCVDLDTNNITV 426
+LLFP ++ Y+P+ P L EVL P P++IGV++ F + DV DLD +T+
Sbjct: 23 ALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAETQELLDVIVADLDGGTVTI 82
Query: 427 CESQRNNISIKLLPKRQVKALKQTLETLYGSIRPASPIHHSSRNRYNGEATTSLDRDFQK 486
E + I LP+ QT L + P + + + T++ Q
Sbjct: 83 PEC----VHIPPLPE---PLQSQTHSVLSMVLDPELELADLA---FPPPTTSTSSLKMQD 132
Query: 487 RKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSREKT 546
+ +++ FLR A LQGYR L + P +P F FL R
Sbjct: 133 K--------ELRAVFLRLFAQLLQGYRWCLHVVRIHP-----EPVIRFHKAAFLGQRGLV 179
Query: 547 QQRFFTLMMRTQMFTRFIEESSFVYDADQGLTFFDECI 584
+ F ++ F F+ E Y + FDE +
Sbjct: 180 EDDFLMKVLEGMAFAGFVSERGVPY---RPTDLFDELV 214
>AK026110-1|BAB15363.1| 468|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22457 fis, clone HRC09925. ).
Length = 468
Score = 55.2 bits (127), Expect = 2e-06
Identities = 53/222 (23%), Positives = 86/222 (38%), Gaps = 17/222 (7%)
Query: 193 SVPLFCLPMGATLELWPNNAASPKPVFSTFVLTVADATEKVYGSAVTFYESYPYSELTET 252
++PLFC P G W + P+ FS FVLT D + K+ G + P L +
Sbjct: 96 AIPLFCFPDGNE---WASLTEYPRETFS-FVLTNVDGSRKI-GYCRRLLPAGPGPRLPKV 150
Query: 253 Q--MELLGWRANVSQNTHSVHVVKSVCLLSRWPFSDTFE--------RWLLYILLSPSNP 302
+ +G S+ V + + PF + + P +
Sbjct: 151 YCIISCIGCFGLFSKILDEVEKRHQISMAVIHPFMQGLREAAFPAPGKTVTLKSFIPDSG 210
Query: 303 SDRVIVTRRDDQPLVRSGASFRQXXXXXXXXXXXXXXXXAITEQKILIHSLRPDTLTAVS 362
++ + +TR D L F A+ E+KI+ + TL+
Sbjct: 211 TEFISLTRPLDSHLEH--VDFSSLLHCLSFEQILQIFASAVLERKIIFLAEGLSTLSQCI 268
Query: 363 EAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
A ++LL+PF W YIP+ P L + P P+++GV RF
Sbjct: 269 HAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRF 310
>BC039703-1|AAH39703.1| 559|Homo sapiens DENN/MADD domain
containing 1A protein.
Length = 559
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 194 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 253
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 254 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 298
>BC028061-1|AAH28061.1| 505|Homo sapiens DENND1A protein protein.
Length = 505
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 201 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 260
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 261 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 305
>BC009616-1|AAH09616.1| 626|Homo sapiens DENND1A protein protein.
Length = 626
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 261 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 320
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 321 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 365
>AL445489-5|CAI39794.1| 466|Homo sapiens DENN/MADD domain
containing 1A protein.
Length = 466
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 162 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 221
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 222 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 266
>AL445489-2|CAI39792.1| 559|Homo sapiens DENN/MADD domain
containing 1A protein.
Length = 559
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 194 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 253
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 254 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 298
>AL445489-1|CAI39791.1| 1009|Homo sapiens DENN/MADD domain
containing 1A protein.
Length = 1009
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 194 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 253
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 254 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 298
>AL390774-4|CAH73640.1| 466|Homo sapiens DENN/MADD domain
containing 1A protein.
Length = 466
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 162 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 221
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 222 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 266
>AL390774-2|CAH73638.1| 559|Homo sapiens DENN/MADD domain
containing 1A protein.
Length = 559
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 194 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 253
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 254 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 298
>AL390774-1|CAH73637.1| 1009|Homo sapiens DENN/MADD domain
containing 1A protein.
Length = 1009
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 194 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 253
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 254 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 298
>AL161790-3|CAI15707.1| 466|Homo sapiens DENN/MADD domain
containing 1A protein.
Length = 466
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 162 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 221
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 222 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 266
>AL161790-2|CAI15706.1| 559|Homo sapiens DENN/MADD domain
containing 1A protein.
Length = 559
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 194 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 253
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 254 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 298
>AL161790-1|CAI15705.1| 1009|Homo sapiens DENN/MADD domain
containing 1A protein.
Length = 1009
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 194 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 253
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 254 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 298
>AK074151-1|BAB84977.1| 896|Homo sapiens FLJ00224 protein protein.
Length = 896
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 81 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 140
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 141 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 185
>AK024782-1|BAB15002.1| 559|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21129 fis, clone CAS06266. ).
Length = 559
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 194 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 253
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 254 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 298
>AB046828-1|BAB13434.2| 872|Homo sapiens KIAA1608 protein protein.
Length = 872
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 345 EQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRF 404
E++ILI + TLTA +++L+P WQ YIP+ P L + AP+PYLIG+
Sbjct: 92 ERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSL 151
Query: 405 FDLYE--PPPDVTCVDLDTNNITVCESQRNNISIKLLPKRQVKALKQTLE 452
+ DV +++DTN + E+ ++ ++ LP + +LK L+
Sbjct: 152 MEKVRNMALDDVVILNVDTNTL---ETPFDD--LQSLPNDVISSLKNRLK 196
>BC133023-1|AAI33024.1| 1146|Homo sapiens DENND3 protein protein.
Length = 1146
Score = 54.0 bits (124), Expect = 4e-06
Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 1/99 (1%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+TEQ+I+ S LT V+E + L+P +WQ P++P+ + + + AP +L+G
Sbjct: 211 LTEQRIVFFSSDWALLTLVTECFMAYLYPLQWQHPFVPILSDQMLDFVMAPTSFLMGCHL 270
Query: 403 RFFDLYEPPPD-VTCVDLDTNNITVCESQRNNISIKLLP 440
F+ D + +++D +IT +S +N+ I +P
Sbjct: 271 DHFEEVSKEADGLVLINIDHGSITYSKSTDDNVDIPDVP 309
>BC033437-1|AAH33437.1| 801|Homo sapiens DENN/MADD domain
containing 1C protein.
Length = 801
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+ E+++L+ + + TLT+ A +LL+P +W+ IP P L + AP+PYLIGV +
Sbjct: 212 LAERRVLLTASKLSTLTSCVHASCALLYPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHA 271
Query: 403 RFFDLYEPP--PDVTCVDLDTNNI 424
+ DV +++D N +
Sbjct: 272 SLAERVREKALEDVVVLNVDANTL 295
>AK026410-1|BAB15475.1| 793|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22757 fis, clone KAIA0803. ).
Length = 793
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Query: 343 ITEQKILIHSLRPDTLTAVSEAVSSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDS 402
+ E+++L+ + + TLT+ A +LL+P +W+ IP P L + AP+PYLIGV +
Sbjct: 212 LAERRVLLTASKLSTLTSCVHASCALLYPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHA 271
Query: 403 RFFDLYEPP--PDVTCVDLDTNNI 424
+ DV +++D N +
Sbjct: 272 SLAERVREKALEDVVVLNVDANTL 295
>X63417-1|CAA45013.1| 191|Homo sapiens IRLB protein.
Length = 191
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/65 (43%), Positives = 36/65 (55%), Gaps = 4/65 (6%)
Query: 1535 KRYYSFYRDILFLAMAALGEQNIDFIALQREYTRALDQLG----REARPQDLPPSPTALC 1590
KR S YR+ILFL++ ALG +NID A +EY A D+L + D PPS +
Sbjct: 122 KRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVME 181
Query: 1591 CRHYF 1595
CR F
Sbjct: 182 CRKTF 186
>AL450998-10|CAH70858.1| 3664|Homo sapiens SMART/HDAC1 associated
repressor protein (SHARP) protein.
Length = 3664
Score = 34.3 bits (75), Expect = 3.6
Identities = 38/175 (21%), Positives = 70/175 (40%), Gaps = 4/175 (2%)
Query: 1064 SKASPLRVSPRTPVLSDDPLGALSVPPVPDEXXXXXXXXXXXXXXXKHELSVSPKLFHRR 1123
S A L +P PV S PL + PPV + K ++PK+
Sbjct: 2563 SAAPCLHEAPPPPVDSKKPLEEKTAPPVTNNSEIQASEVLVAADKEKVAPVIAPKITSVI 2622
Query: 1124 SNSFQDDPPEQLGKLHRSETVPAGTVSSSLVSLGNTLKLNFGPTS-MAG--KKSNELLQS 1180
S E K+ ++ P T++ + +L + ++ P + + G K S L+S
Sbjct: 2623 SRMPVSIDLENSQKITLAKPAPQ-TLTGLVSALTGLVNVSLVPVNALKGPVKGSVTTLKS 2681
Query: 1181 GLSSLKSAATSMAKKFDEMKEVISANSTPVKGAIGTATSALGAFRADDDGVDASS 1235
+S+ + + + ++ +TPV +GT +A G A V+A++
Sbjct: 2682 LVSTPAGPVNVLKGPVNVLTGPVNVLTTPVNATVGTVNAAPGTVNAAASAVNATA 2736
>AL096858-1|CAB51072.1| 3261|Homo sapiens hypothetical protein
protein.
Length = 3261
Score = 34.3 bits (75), Expect = 3.6
Identities = 38/175 (21%), Positives = 70/175 (40%), Gaps = 4/175 (2%)
Query: 1064 SKASPLRVSPRTPVLSDDPLGALSVPPVPDEXXXXXXXXXXXXXXXKHELSVSPKLFHRR 1123
S A L +P PV S PL + PPV + K ++PK+
Sbjct: 2160 SAAPCLHEAPPPPVDSKKPLEEKTAPPVTNNSEIQASEVLVAADKEKVAPVIAPKITSVI 2219
Query: 1124 SNSFQDDPPEQLGKLHRSETVPAGTVSSSLVSLGNTLKLNFGPTS-MAG--KKSNELLQS 1180
S E K+ ++ P T++ + +L + ++ P + + G K S L+S
Sbjct: 2220 SRMPVSIDLENSQKITLAKPAPQ-TLTGLVSALTGLVNVSLVPVNALKGPVKGSVTTLKS 2278
Query: 1181 GLSSLKSAATSMAKKFDEMKEVISANSTPVKGAIGTATSALGAFRADDDGVDASS 1235
+S+ + + + ++ +TPV +GT +A G A V+A++
Sbjct: 2279 LVSTPAGPVNVLKGPVNVLTGPVNVLTTPVNATVGTVNAAPGTVNAAASAVNATA 2333
>AL034555-4|CAI19526.1| 3664|Homo sapiens SMART/HDAC1 associated
repressor protein (SHARP) protein.
Length = 3664
Score = 34.3 bits (75), Expect = 3.6
Identities = 38/175 (21%), Positives = 70/175 (40%), Gaps = 4/175 (2%)
Query: 1064 SKASPLRVSPRTPVLSDDPLGALSVPPVPDEXXXXXXXXXXXXXXXKHELSVSPKLFHRR 1123
S A L +P PV S PL + PPV + K ++PK+
Sbjct: 2563 SAAPCLHEAPPPPVDSKKPLEEKTAPPVTNNSEIQASEVLVAADKEKVAPVIAPKITSVI 2622
Query: 1124 SNSFQDDPPEQLGKLHRSETVPAGTVSSSLVSLGNTLKLNFGPTS-MAG--KKSNELLQS 1180
S E K+ ++ P T++ + +L + ++ P + + G K S L+S
Sbjct: 2623 SRMPVSIDLENSQKITLAKPAPQ-TLTGLVSALTGLVNVSLVPVNALKGPVKGSVTTLKS 2681
Query: 1181 GLSSLKSAATSMAKKFDEMKEVISANSTPVKGAIGTATSALGAFRADDDGVDASS 1235
+S+ + + + ++ +TPV +GT +A G A V+A++
Sbjct: 2682 LVSTPAGPVNVLKGPVNVLTGPVNVLTTPVNATVGTVNAAPGTVNAAASAVNATA 2736
>AF356524-1|AAK52750.1| 3664|Homo sapiens nuclear receptor
transcription cofactor protein.
Length = 3664
Score = 34.3 bits (75), Expect = 3.6
Identities = 38/175 (21%), Positives = 70/175 (40%), Gaps = 4/175 (2%)
Query: 1064 SKASPLRVSPRTPVLSDDPLGALSVPPVPDEXXXXXXXXXXXXXXXKHELSVSPKLFHRR 1123
S A L +P PV S PL + PPV + K ++PK+
Sbjct: 2563 SAAPCLHEAPPPPVDSKKPLEEKTAPPVTNNSEIQASEVLVAADKEKVAPVIAPKITSVI 2622
Query: 1124 SNSFQDDPPEQLGKLHRSETVPAGTVSSSLVSLGNTLKLNFGPTS-MAG--KKSNELLQS 1180
S E K+ ++ P T++ + +L + ++ P + + G K S L+S
Sbjct: 2623 SRMPVSIDLENSQKITLAKPAPQ-TLTGLVSALTGLVNVSLVPVNALKGPVKGSVTTLKS 2681
Query: 1181 GLSSLKSAATSMAKKFDEMKEVISANSTPVKGAIGTATSALGAFRADDDGVDASS 1235
+S+ + + + ++ +TPV +GT +A G A V+A++
Sbjct: 2682 LVSTPAGPVNVLKGPVNVLTGPVNVLTTPVNATVGTVNAAPGTVNAAASAVNATA 2736
>AB023146-1|BAA76773.1| 1663|Homo sapiens KIAA0929 protein protein.
Length = 1663
Score = 34.3 bits (75), Expect = 3.6
Identities = 38/175 (21%), Positives = 70/175 (40%), Gaps = 4/175 (2%)
Query: 1064 SKASPLRVSPRTPVLSDDPLGALSVPPVPDEXXXXXXXXXXXXXXXKHELSVSPKLFHRR 1123
S A L +P PV S PL + PPV + K ++PK+
Sbjct: 562 SAAPCLHEAPPPPVDSKKPLEEKTAPPVTNNSEIQASEVLVAADKEKVAPVIAPKITSVI 621
Query: 1124 SNSFQDDPPEQLGKLHRSETVPAGTVSSSLVSLGNTLKLNFGPTS-MAG--KKSNELLQS 1180
S E K+ ++ P T++ + +L + ++ P + + G K S L+S
Sbjct: 622 SRMPVSIDLENSQKITLAKPAPQ-TLTGLVSALTGLVNVSLVPVNALKGPVKGSVTTLKS 680
Query: 1181 GLSSLKSAATSMAKKFDEMKEVISANSTPVKGAIGTATSALGAFRADDDGVDASS 1235
+S+ + + + ++ +TPV +GT +A G A V+A++
Sbjct: 681 LVSTPAGPVNVLKGPVNVLTGPVNVLTTPVNATVGTVNAAPGTVNAAASAVNATA 735
>BC009354-1|AAH09354.2| 948|Homo sapiens RAB6IP1 protein protein.
Length = 948
Score = 33.9 bits (74), Expect = 4.8
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 5/56 (8%)
Query: 378 YIPLCPLGLAEVLHAPLPYLIGVDSRFFD----LYEPPPDVTC-VDLDTNNITVCE 428
Y+P+ P L L AP+PYL+G+ S D L P C VD+D + I + E
Sbjct: 2 YVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELPE 57
>BC063894-1|AAH63894.1| 816|Homo sapiens DENND2C protein protein.
Length = 816
Score = 33.5 bits (73), Expect = 6.3
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 9/94 (9%)
Query: 485 QKRKKEQALELKIQEAFLRFMACTLQGYRSYLIPITKAPTVGTTDPDALFQMNEFLRSR- 543
Q ++ L + EAF+RF L G+ S + +T+ + +FQ F +S
Sbjct: 694 QNFSQDVTLNSLVSEAFVRFFV-ELVGHYSLNMTVTERG-------ERVFQREPFRKSHT 745
Query: 544 EKTQQRFFTLMMRTQMFTRFIEESSFVYDADQGL 577
++ + F L M TQMF FI++ +GL
Sbjct: 746 SRSVRHFLDLFMETQMFAGFIQDRELRKSGVKGL 779
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 214,363,964
Number of Sequences: 224733
Number of extensions: 8568902
Number of successful extensions: 21924
Number of sequences better than 10.0: 89
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 21562
Number of HSP's gapped (non-prelim): 265
length of query: 1604
length of database: 73,234,838
effective HSP length: 100
effective length of query: 1504
effective length of database: 50,761,538
effective search space: 76345353152
effective search space used: 76345353152
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 72 (33.1 bits)
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