Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001509-TA|BGIBMGA001509-PA|IPR001680|WD-40 repeat,
IPR011046|WD40-like
(527 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AK074217-1|BAB85020.1| 506|Homo sapiens protein ( Homo sapiens ... 383 e-105
BC013064-1|AAH13064.1| 285|Homo sapiens UTP15 protein protein. 154 6e-37
AK022849-1|BAB14271.1| 285|Homo sapiens protein ( Homo sapiens ... 154 6e-37
CR457295-1|CAG33576.1| 285|Homo sapiens FLJ12787 protein. 152 3e-36
AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kD... 100 1e-20
EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein. 99 3e-20
BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5... 99 3e-20
AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5... 99 3e-20
AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor p... 99 4e-20
BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein. 96 2e-19
BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A pr... 96 2e-19
BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein. 96 2e-19
BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein. 96 2e-19
AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens ... 96 3e-19
CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein. 94 1e-18
BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80 (WD40-conta... 94 1e-18
BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat ... 94 1e-18
CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein. 92 5e-18
BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B pro... 92 5e-18
AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens ... 92 5e-18
AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit pro... 88 6e-17
EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein. 87 1e-16
BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B pr... 87 1e-16
AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens ... 87 1e-16
BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5 prot... 85 6e-16
BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5 prot... 85 6e-16
AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens ... 85 6e-16
AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein pr... 85 6e-16
BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1... 84 1e-15
BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein. 84 1e-15
AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1... 84 1e-15
AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymeras... 79 5e-14
AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription ... 79 5e-14
AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor ... 79 5e-14
BC127949-1|AAI27950.1| 314|Homo sapiens similar to hypothetical... 78 9e-14
AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38 pro... 77 2e-13
X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein. 77 2e-13
U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100 pr... 77 2e-13
U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor pro... 77 2e-13
BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,... 77 2e-13
AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,... 77 2e-13
AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiatio... 77 2e-13
BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein. 76 4e-13
U72342-1|AAC51111.1| 410|Homo sapiens platelet activating facto... 74 1e-12
L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencepha... 74 1e-12
L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencepha... 74 1e-12
L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencepha... 74 1e-12
BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat dom... 74 1e-12
BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat dom... 74 1e-12
BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating fac... 74 1e-12
BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein. 74 1e-12
AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4 prot... 74 1e-12
AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7 prot... 74 1e-12
AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10 pro... 74 1e-12
AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isof... 74 1e-12
AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens ... 74 1e-12
AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens ... 74 1e-12
AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form p... 74 1e-12
AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form ... 74 1e-12
AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating fac... 74 1e-12
AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30 pro... 74 1e-12
AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker lissencep... 74 1e-12
AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker lissencep... 74 1e-12
AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isof... 74 1e-12
X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer compl... 73 3e-12
BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein comple... 73 3e-12
BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69 pro... 72 4e-12
AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens ... 72 4e-12
AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein. 72 4e-12
AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens ... 71 8e-12
AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens ... 71 1e-11
BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide bind... 70 2e-11
AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide bind... 70 2e-11
AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide bind... 70 2e-11
AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subuni... 70 2e-11
BC005870-1|AAH05870.1| 315|Homo sapiens mitogen-activated prote... 69 3e-11
AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein. 69 3e-11
AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein. 69 3e-11
BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS box-... 69 4e-11
BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 69 4e-11
BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 69 4e-11
BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 69 4e-11
AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens ... 69 4e-11
AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein ... 69 4e-11
AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein. 69 4e-11
AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD ... 69 4e-11
AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein. 69 4e-11
BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61 pro... 69 5e-11
AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens ... 69 5e-11
AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination p... 69 5e-11
AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta subunit-... 69 5e-11
AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein. 68 7e-11
AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein. 68 7e-11
X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRN... 68 9e-11
M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transduci... 68 9e-11
CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein. 68 9e-11
BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide bind... 68 9e-11
BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide bind... 68 9e-11
BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide bind... 68 9e-11
BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide bind... 68 9e-11
AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide bind... 68 9e-11
AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide bin... 68 9e-11
AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide bind... 68 9e-11
AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide bind... 68 9e-11
AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal tra... 68 9e-11
AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein. 67 1e-10
BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat dom... 67 2e-10
AK223195-1|BAD96915.1| 315|Homo sapiens mitogen-activated prote... 67 2e-10
AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b pro... 67 2e-10
AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats pr... 67 2e-10
AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats pr... 67 2e-10
AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats pr... 67 2e-10
AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein. 67 2e-10
L07758-1|AAA65201.1| 501|Homo sapiens IEF SSP 9502 protein. 66 2e-10
BC001652-1|AAH01652.1| 501|Homo sapiens PWP1 homolog (S. cerevi... 66 2e-10
AK223162-1|BAD96882.1| 501|Homo sapiens nuclear phosphoprotein ... 66 2e-10
AF492460-1|AAN64030.1| 1322|Homo sapiens WD repeat 17 protein. 66 2e-10
CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein. 66 3e-10
Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats c... 66 4e-10
BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat ... 66 4e-10
AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat... 66 4e-10
AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat... 66 4e-10
AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat ... 66 4e-10
AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat ... 66 4e-10
AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat ... 66 4e-10
AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat ... 66 4e-10
AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1 i... 66 4e-10
AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A pro... 66 4e-10
AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant E3RS-Ika... 66 4e-10
BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide bind... 65 7e-10
AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide bind... 65 7e-10
AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide bind... 65 7e-10
M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.... 63 2e-09
CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein. 63 2e-09
CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein. 63 2e-09
BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide bind... 63 2e-09
BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide bind... 63 2e-09
BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide bind... 63 2e-09
BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide bind... 63 2e-09
BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide bind... 63 2e-09
BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide bind... 63 2e-09
BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide bind... 63 2e-09
BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide bind... 63 2e-09
BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide bind... 63 2e-09
BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide bind... 63 2e-09
AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7 ... 63 2e-09
AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease acti... 63 2e-09
BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide bind... 63 3e-09
BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide bind... 63 3e-09
BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide bind... 63 3e-09
AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease acti... 63 3e-09
AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating fac... 63 3e-09
AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease acti... 63 3e-09
AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease acti... 63 3e-09
AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease acti... 63 3e-09
AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease acti... 63 3e-09
AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease acti... 63 3e-09
AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease acti... 63 3e-09
AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease acti... 63 3e-09
AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein. 63 3e-09
Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-bindin... 62 4e-09
U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain pr... 62 4e-09
M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein. 62 4e-09
AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide bind... 62 4e-09
AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide bind... 62 4e-09
AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-bind... 62 4e-09
BC014988-1|AAH14988.1| 919|Homo sapiens PWP2 periodic tryptopha... 62 5e-09
BC013309-1|AAH13309.1| 919|Homo sapiens PWP2 periodic tryptopha... 62 5e-09
AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease acti... 62 5e-09
M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transduci... 61 8e-09
M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein. 61 8e-09
CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein. 61 8e-09
BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein. 61 8e-09
BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide bind... 61 8e-09
BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide bind... 61 8e-09
BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide bind... 61 8e-09
AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease acti... 61 8e-09
AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide bind... 61 8e-09
AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein. 61 8e-09
BC126114-1|AAI26115.1| 579|Homo sapiens cell division cycle 40 ... 61 1e-08
BC117145-1|AAI17146.1| 579|Homo sapiens cell division cycle 40 ... 61 1e-08
BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS box-... 61 1e-08
AL671518-2|CAI13322.1| 579|Homo sapiens cell division cycle 40 ... 61 1e-08
AL671518-1|CAI13321.1| 539|Homo sapiens cell division cycle 40 ... 61 1e-08
AL445068-1|CAI22519.1| 539|Homo sapiens cell division cycle 40 ... 61 1e-08
AK222721-1|BAD96441.1| 579|Homo sapiens pre-mRNA splicing facto... 61 1e-08
AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease acti... 61 1e-08
AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD pr... 61 1e-08
AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein. 61 1e-08
AF061241-1|AAC25166.1| 542|Homo sapiens splicing factor hPRP17 ... 61 1e-08
AF038392-1|AAC39730.1| 579|Homo sapiens pre-mRNA splicing facto... 61 1e-08
AB208903-1|BAD92140.1| 501|Homo sapiens pre-mRNA splicing facto... 61 1e-08
X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein. 60 1e-08
U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan prote... 60 1e-08
U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan prote... 60 1e-08
U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein. 60 1e-08
AP001753-1|BAA95553.1| 919|Homo sapiens periodic tryptophan pro... 60 1e-08
AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta subunit-... 60 1e-08
AB001517-2|BAA21137.1| 919|Homo sapiens PWP2 protein protein. 60 1e-08
U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein. 60 2e-08
BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein. 60 2e-08
AL513282-3|CAI12455.1| 1233|Homo sapiens coatomer protein comple... 60 2e-08
AL513282-2|CAI12454.1| 1224|Homo sapiens coatomer protein comple... 60 2e-08
AL445230-2|CAI15005.1| 1224|Homo sapiens coatomer protein comple... 60 2e-08
AL445230-1|CAI15004.1| 1233|Homo sapiens coatomer protein comple... 60 2e-08
AB209438-1|BAD92675.1| 316|Homo sapiens PWP2 periodic tryptopha... 60 2e-08
BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1 (Dr... 60 3e-08
BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein. 60 3e-08
AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens ... 60 3e-08
AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease acti... 60 3e-08
AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog ... 60 3e-08
M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human signal-tr... 59 3e-08
AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa prot... 59 3e-08
CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein. 58 6e-08
BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processin... 58 6e-08
BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processin... 58 6e-08
AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6 snRNP-spec... 58 6e-08
AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processin... 58 6e-08
AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processin... 58 6e-08
AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear rib... 58 6e-08
AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant p... 58 6e-08
U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p... 58 1e-07
AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3 prot... 58 1e-07
AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3 ... 58 1e-07
BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein. 57 1e-07
BC047921-1|AAH47921.1| 563|Homo sapiens WDR86 protein protein. 57 2e-07
EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein. 56 2e-07
BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec... 56 2e-07
BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec... 56 2e-07
AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec... 56 2e-07
AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD rep... 56 2e-07
AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein. 56 2e-07
BC024267-1|AAH24267.1| 594|Homo sapiens TRAF7 protein protein. 56 3e-07
AY569455-1|AAS68363.1| 670|Homo sapiens TRAF7 protein. 56 3e-07
BC107125-1|AAI07126.1| 248|Homo sapiens WDR86 protein protein. 55 5e-07
CR456496-1|CAG30382.1| 327|Homo sapiens GNB1L protein. 54 9e-07
BC012060-1|AAH12060.1| 327|Homo sapiens guanine nucleotide bind... 54 9e-07
AF301895-1|AAG53933.1| 327|Homo sapiens WDVCF protein. 54 9e-07
AB051432-1|BAB33315.1| 386|Homo sapiens KIAA1645 protein protein. 54 9e-07
AB049212-1|BAB68408.1| 327|Homo sapiens G-protein beta subunit ... 54 9e-07
BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein. 54 1e-06
AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing ... 54 1e-06
AK222483-1|BAD96203.1| 325|Homo sapiens eukaryotic translation ... 54 1e-06
U39067-1|AAC97144.1| 325|Homo sapiens translation initiation fa... 53 2e-06
U36764-1|AAC50224.1| 325|Homo sapiens TGF-beta receptor interac... 53 2e-06
BT019597-1|AAV38404.1| 325|Homo sapiens eukaryotic translation ... 53 2e-06
BC003140-1|AAH03140.1| 325|Homo sapiens eukaryotic translation ... 53 2e-06
BC000413-1|AAH00413.1| 325|Homo sapiens eukaryotic translation ... 53 2e-06
AY295082-1|AAQ63174.1| 544|Homo sapiens pre-mRNA splicing facto... 53 2e-06
AL121991-4|CAI22322.1| 325|Homo sapiens eukaryotic translation ... 53 2e-06
AL049795-10|CAI22061.1| 325|Homo sapiens eukaryotic translation... 53 2e-06
BC130473-1|AAI30474.1| 522|Homo sapiens transducin (beta)-like ... 53 3e-06
BC130471-1|AAI30472.1| 522|Homo sapiens transducin (beta)-like ... 53 3e-06
BC032523-1|AAH32523.1| 676|Homo sapiens WD and tetratricopeptid... 53 3e-06
AL663123-11|CAI14787.1| 676|Homo sapiens WD and tetratricopepti... 53 3e-06
AL590640-1|CAH73549.1| 676|Homo sapiens WD and tetratricopeptid... 53 3e-06
AK001734-1|BAA91868.1| 615|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AF332222-1|AAK13474.1| 522|Homo sapiens transducin beta-like 1 ... 53 3e-06
AF332221-1|AAK13473.1| 522|Homo sapiens transducin beta-like 1 ... 53 3e-06
AF332220-1|AAK13472.1| 522|Homo sapiens transducin beta-like 1 ... 53 3e-06
AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein. 53 3e-06
BC028364-1|AAH28364.1| 1061|Homo sapiens FBXW10 protein protein. 52 5e-06
AY729024-1|AAU43731.1| 1052|Homo sapiens ubiquitin ligase specif... 52 5e-06
AB209899-1|BAD93136.1| 967|Homo sapiens Hypothetical protein DK... 52 5e-06
Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1 ... 52 7e-06
U84720-1|AAC28126.1| 368|Homo sapiens mRNA export protein protein. 52 7e-06
BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like ... 52 7e-06
BC106924-1|AAI06925.1| 368|Homo sapiens RAE1 RNA export 1 homol... 52 7e-06
BC106923-1|AAI06924.1| 368|Homo sapiens RAE1 RNA export 1 homol... 52 7e-06
BC103754-1|AAI03755.1| 368|Homo sapiens RAE1 RNA export 1 homol... 52 7e-06
BC052304-1|AAH52304.1| 577|Homo sapiens transducin (beta)-like ... 52 7e-06
BC032708-1|AAH32708.1| 526|Homo sapiens TBL1X protein protein. 52 7e-06
BC000201-1|AAH00201.1| 606|Homo sapiens WD repeat domain 1 prot... 52 7e-06
AY349350-1|AAR04856.1| 368|Homo sapiens RNA export 1-like prote... 52 7e-06
AY336091-1|AAR24621.1| 352|Homo sapiens migration-inducing gene... 52 7e-06
AL135939-7|CAI21524.1| 368|Homo sapiens RAE1 RNA export 1 homol... 52 7e-06
AK222897-1|BAD96617.1| 606|Homo sapiens WD repeat-containing pr... 52 7e-06
AK222764-1|BAD96484.1| 606|Homo sapiens WD repeat-containing pr... 52 7e-06
AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens ... 52 7e-06
AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor co-rep... 52 7e-06
AF240696-1|AAF82746.1| 275|Homo sapiens WSB1 isoform 2 protein. 52 7e-06
AB209746-1|BAD92983.1| 624|Homo sapiens WD repeat-containing pr... 52 7e-06
AB209608-1|BAD92845.1| 540|Homo sapiens transducin beta-like 1X... 52 7e-06
BC117291-1|AAI17292.1| 925|Homo sapiens coronin 7 protein. 51 9e-06
BC117289-1|AAI17290.1| 925|Homo sapiens coronin 7 protein. 51 9e-06
BC068499-1|AAH68499.1| 351|Homo sapiens THO complex 3 protein. 51 9e-06
BC066325-1|AAH66325.1| 327|Homo sapiens THOC3 protein protein. 51 9e-06
BC006849-1|AAH06849.1| 351|Homo sapiens THO complex 3 protein. 51 9e-06
BC002489-1|AAH02489.1| 606|Homo sapiens WD repeat domain 1 prot... 51 9e-06
AK025674-1|BAB15211.1| 925|Homo sapiens protein ( Homo sapiens ... 51 9e-06
AF020260-1|AAD05045.1| 534|Homo sapiens WDR1 protein protein. 51 9e-06
AF020056-1|AAD05044.1| 606|Homo sapiens WDR1 protein protein. 51 9e-06
AB209201-1|BAD92438.1| 466|Homo sapiens WD repeat-containing pr... 51 9e-06
AB010427-1|BAA31855.2| 606|Homo sapiens NORI-1 protein. 51 9e-06
BC110334-1|AAI10335.1| 454|Homo sapiens F-box and WD repeat dom... 51 1e-05
BC023662-1|AAH23662.2| 475|Homo sapiens RRP9, small subunit (SS... 51 1e-05
BC018738-1|AAH18738.1| 454|Homo sapiens F-box and WD repeat dom... 51 1e-05
BC010048-1|AAH10048.1| 475|Homo sapiens RRP9, small subunit (SS... 51 1e-05
BC009879-1|AAH09879.1| 475|Homo sapiens RRP9, small subunit (SS... 51 1e-05
BC001113-1|AAH01113.1| 475|Homo sapiens RRP9, small subunit (SS... 51 1e-05
AL161911-3|CAI95114.1| 208|Homo sapiens F-box and WD-40 domain ... 51 1e-05
AL161911-2|CAI95113.1| 454|Homo sapiens F-box and WD-40 domain ... 51 1e-05
AK022484-1|BAB14051.1| 454|Homo sapiens protein ( Homo sapiens ... 51 1e-05
AJ001340-1|CAA04687.1| 475|Homo sapiens U3 snoRNP associated 55... 51 1e-05
AF176698-1|AAF13226.1| 422|Homo sapiens F-box protein FBW2 prot... 51 1e-05
AF145024-1|AAP97276.1| 422|Homo sapiens MD6 protein protein. 51 1e-05
AF129531-1|AAF04465.1| 422|Homo sapiens F-box protein Fbw2 prot... 51 1e-05
U86136-1|AAC51107.1| 2627|Homo sapiens telomerase-associated pro... 50 2e-05
M99436-1|AAA61193.1| 743|Homo sapiens transducin-like enhancer ... 50 2e-05
BC126107-1|AAI26108.1| 2627|Homo sapiens telomerase-associated p... 50 2e-05
AB209669-1|BAD92906.1| 1903|Homo sapiens Telomerase protein comp... 50 2e-05
U85943-1|AAC28127.1| 368|Homo sapiens mRNA-associated protein m... 50 2e-05
BC035512-1|AAH35512.1| 697|Homo sapiens WD repeat domain 49 pro... 49 4e-05
BC017364-1|AAH17364.1| 743|Homo sapiens transducin-like enhance... 49 4e-05
AC007766-2|AAD38075.1| 553|Homo sapiens TLE2_HUMAN [AA 191- 743... 49 4e-05
AK093494-1|BAC04184.1| 476|Homo sapiens protein ( Homo sapiens ... 49 5e-05
U63810-1|AAC24948.1| 339|Homo sapiens WD40 protein Ciao 1 protein. 48 6e-05
EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related... 48 6e-05
EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related... 48 6e-05
EF011618-1|ABK41108.1| 339|Homo sapiens CDW8/WDR39 protein. 48 6e-05
CR456802-1|CAG33083.1| 339|Homo sapiens CIAO1 protein. 48 6e-05
BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein. 48 6e-05
BC094728-1|AAH94728.1| 731|Homo sapiens ring finger and WD repe... 48 6e-05
BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein. 48 6e-05
BC032812-1|AAH32812.1| 339|Homo sapiens cytosolic iron-sulfur p... 48 6e-05
BC001395-1|AAH01395.1| 339|Homo sapiens cytosolic iron-sulfur p... 48 6e-05
AY509921-1|AAS82851.1| 707|Homo sapiens constitutive photomorph... 48 6e-05
AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein. 48 6e-05
AL590723-3|CAI14643.1| 731|Homo sapiens ring finger and WD repe... 48 6e-05
AL590723-2|CAI14642.1| 564|Homo sapiens ring finger and WD repe... 48 6e-05
AL590723-1|CAI14641.1| 491|Homo sapiens ring finger and WD repe... 48 6e-05
AL513329-4|CAH72425.1| 731|Homo sapiens ring finger and WD repe... 48 6e-05
AL513329-2|CAH72423.1| 564|Homo sapiens ring finger and WD repe... 48 6e-05
AL513329-1|CAH72422.1| 491|Homo sapiens ring finger and WD repe... 48 6e-05
AL359265-3|CAH71140.1| 731|Homo sapiens ring finger and WD repe... 48 6e-05
AL359265-2|CAH71139.1| 564|Homo sapiens ring finger and WD repe... 48 6e-05
AL359265-1|CAH71138.1| 491|Homo sapiens ring finger and WD repe... 48 6e-05
AL162736-3|CAH73625.1| 731|Homo sapiens ring finger and WD repe... 48 6e-05
AL162736-2|CAH73624.1| 564|Homo sapiens ring finger and WD repe... 48 6e-05
AL162736-1|CAH73623.1| 491|Homo sapiens ring finger and WD repe... 48 6e-05
AK223257-1|BAD96977.1| 339|Homo sapiens WD40 protein Ciao1 vari... 48 6e-05
AK025789-1|BAB15239.1| 506|Homo sapiens protein ( Homo sapiens ... 48 6e-05
AF527539-1|AAQ08989.1| 731|Homo sapiens putative ubiquitin liga... 48 6e-05
AF508940-1|AAM34692.1| 731|Homo sapiens constitutive photomorph... 48 6e-05
AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein. 48 6e-05
AC004020-1|AAC23493.1| 339|Homo sapiens Unknown gene product pr... 48 6e-05
X74262-1|CAA52321.1| 425|Homo sapiens retinoblastoma binding pr... 48 8e-05
X71810-1|CAA50685.1| 410|Homo sapiens IEF SSP 9306 protein. 48 8e-05
EF011612-1|ABK41102.1| 514|Homo sapiens CDW2/WDR26 protein. 48 8e-05
BT007309-1|AAP35973.1| 425|Homo sapiens retinoblastoma binding ... 48 8e-05
BC075836-1|AAH75836.1| 425|Homo sapiens retinoblastoma binding ... 48 8e-05
BC063817-1|AAH63817.1| 404|Homo sapiens WDR26 protein protein. 48 8e-05
BC053904-1|AAH53904.1| 425|Homo sapiens retinoblastoma binding ... 48 8e-05
BC052301-1|AAH52301.2| 514|Homo sapiens WD repeat domain 26 pro... 48 8e-05
BC031471-1|AAH31471.2| 373|Homo sapiens WDR26 protein protein. 48 8e-05
BC026353-1|AAH26353.1| 677|Homo sapiens WD repeat domain 48 pro... 48 8e-05
BC015123-1|AAH15123.1| 365|Homo sapiens Similar to retinoblasto... 48 8e-05
BC003092-1|AAH03092.1| 425|Homo sapiens retinoblastoma binding ... 48 8e-05
AY304473-1|AAQ74770.1| 514|Homo sapiens WD40 repeat protein 26 ... 48 8e-05
AY221751-1|AAO67709.1| 498|Homo sapiens myocardial ischemic pre... 48 8e-05
AK222779-1|BAD96499.1| 424|Homo sapiens retinoblastoma binding ... 48 8e-05
AK024669-1|BAB14955.1| 367|Homo sapiens protein ( Homo sapiens ... 48 8e-05
AF468833-1|AAL78650.1| 677|Homo sapiens WD repeat endosomal pro... 48 8e-05
AB209887-1|BAD93124.1| 725|Homo sapiens WD repeat domain 26 var... 48 8e-05
AB040882-1|BAA95973.2| 680|Homo sapiens KIAA1449 protein protein. 48 8e-05
U88871-1|AAC51238.1| 323|Homo sapiens HsPex7p protein. 48 1e-04
U76560-1|AAB50556.1| 323|Homo sapiens peroxisome targeting sign... 48 1e-04
CR542076-1|CAG46873.1| 323|Homo sapiens PEX7 protein. 48 1e-04
CR542054-1|CAG46851.1| 323|Homo sapiens PEX7 protein. 48 1e-04
BC022967-1|AAH22967.1| 326|Homo sapiens WDR22 protein protein. 48 1e-04
BC006268-1|AAH06268.1| 323|Homo sapiens peroxisomal biogenesis ... 48 1e-04
BC001648-1|AAH01648.1| 432|Homo sapiens WD repeat domain 18 pro... 48 1e-04
BC000040-1|AAH00040.2| 432|Homo sapiens WD repeat domain 18 pro... 48 1e-04
AL365223-4|CAI15714.1| 323|Homo sapiens peroxisomal biogenesis ... 48 1e-04
AL121933-2|CAI15471.1| 323|Homo sapiens peroxisomal biogenesis ... 48 1e-04
AK123876-1|BAC85713.1| 428|Homo sapiens protein ( Homo sapiens ... 48 1e-04
AK074434-1|BAB85082.1| 293|Homo sapiens protein ( Homo sapiens ... 48 1e-04
AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens ... 48 1e-04
AF180814-1|AAF37350.1| 323|Homo sapiens peroxisomal PTS2 recept... 48 1e-04
AB058727-1|BAB47453.1| 958|Homo sapiens KIAA1824 protein protein. 48 1e-04
BC063041-1|AAH63041.1| 1129|Homo sapiens WD repeat and HMG-box D... 47 2e-04
BC043349-1|AAH43349.1| 612|Homo sapiens WDHD1 protein protein. 47 2e-04
BC005040-1|AAH05040.1| 613|Homo sapiens Unknown (protein for IM... 47 2e-04
BC000622-1|AAH00622.1| 613|Homo sapiens WDHD1 protein protein. 47 2e-04
AJ006266-1|CAA06932.1| 1129|Homo sapiens AND-1 protein protein. 47 2e-04
X72841-1|CAA51360.1| 425|Homo sapiens IEF 7442 protein. 46 3e-04
U35143-1|AAC50231.1| 425|Homo sapiens retinoblastoma-binding pr... 46 3e-04
L02547-1|AAA35691.1| 431|Homo sapiens cleavage stimulation fact... 46 3e-04
CR541701-1|CAG46502.1| 425|Homo sapiens RBBP7 protein. 46 3e-04
BT007138-1|AAP35802.1| 431|Homo sapiens cleavage stimulation fa... 46 3e-04
BC114501-1|AAI14502.1| 425|Homo sapiens retinoblastoma binding ... 46 3e-04
BC114500-1|AAI14501.1| 425|Homo sapiens retinoblastoma binding ... 46 3e-04
BC007425-1|AAH07425.1| 431|Homo sapiens cleavage stimulation fa... 46 3e-04
BC001011-1|AAH01011.1| 431|Homo sapiens cleavage stimulation fa... 46 3e-04
AL929302-6|CAI41284.1| 420|Homo sapiens retinoblastoma binding ... 46 3e-04
AL929302-5|CAI41283.1| 469|Homo sapiens retinoblastoma binding ... 46 3e-04
AL121914-12|CAI19328.1| 431|Homo sapiens cleavage stimulation f... 46 3e-04
AL121914-11|CAC12718.2| 345|Homo sapiens cleavage stimulation f... 46 3e-04
AB007918-1|BAA32294.2| 1628|Homo sapiens KIAA0449 protein protein. 46 3e-04
BX679664-5|CAH71327.1| 919|Homo sapiens WD repeat domain 47 pro... 46 4e-04
BX679664-4|CAH71326.1| 920|Homo sapiens WD repeat domain 47 pro... 46 4e-04
BX679664-3|CAH71325.1| 891|Homo sapiens WD repeat domain 47 pro... 46 4e-04
AL607085-2|CAI15166.1| 494|Homo sapiens novel protein protein. 46 4e-04
AL449266-4|CAI14352.1| 891|Homo sapiens WD repeat domain 47 pro... 46 4e-04
AL449266-3|CAI14353.1| 919|Homo sapiens WD repeat domain 47 pro... 46 4e-04
AL449266-2|CAI14351.1| 920|Homo sapiens WD repeat domain 47 pro... 46 4e-04
AB023199-1|BAA76826.2| 502|Homo sapiens KIAA0982 protein protein. 46 4e-04
AB020700-1|BAA74916.2| 974|Homo sapiens KIAA0893 protein protein. 46 4e-04
D83782-1|BAA12111.2| 1283|Homo sapiens KIAA0199 protein. 45 6e-04
BC020987-1|AAH20987.1| 905|Homo sapiens SCAP protein protein. 45 6e-04
AK075528-1|BAC11673.1| 379|Homo sapiens protein ( Homo sapiens ... 45 6e-04
AK027402-1|BAB55088.1| 886|Homo sapiens protein ( Homo sapiens ... 45 6e-04
AJ005257-1|CAA06444.1| 86|Homo sapiens protein ( Homo sapiens ... 45 6e-04
BC031606-1|AAH31606.1| 280|Homo sapiens PEX7 protein protein. 45 8e-04
BC003641-1|AAH03641.1| 287|Homo sapiens WDR25 protein protein. 45 8e-04
BX538346-1|CAD98141.1| 147|Homo sapiens hypothetical protein pr... 44 0.001
BC113614-1|AAI13615.1| 1508|Homo sapiens gem (nuclear organelle)... 44 0.001
BC036894-1|AAH36894.1| 746|Homo sapiens GEMIN5 protein protein. 44 0.001
BC014147-1|AAH14147.2| 921|Homo sapiens GEMIN5 protein protein. 44 0.001
BC008776-1|AAH08776.2| 921|Homo sapiens GEMIN5 protein protein. 44 0.001
AY063750-1|AAL38980.1| 1508|Homo sapiens WD repeat protein Gemin... 44 0.001
AK074066-1|BAB84892.1| 1512|Homo sapiens FLJ00137 protein protein. 44 0.001
AK022748-1|BAB14222.1| 741|Homo sapiens protein ( Homo sapiens ... 44 0.001
U20980-1|AAA76737.1| 559|Homo sapiens chromatin assembly factor... 44 0.001
M99439-1|AAA61195.1| 448|Homo sapiens transducin-like enhancer ... 44 0.001
DQ641253-1|ABG23317.1| 730|Homo sapiens CDW1 protein. 44 0.001
BC059405-1|AAH59405.2| 805|Homo sapiens TLE4 protein protein. 44 0.001
BC045650-1|AAH45650.1| 704|Homo sapiens TLE4 protein protein. 44 0.001
BC039254-1|AAH39254.1| 893|Homo sapiens WDR47 protein protein. 44 0.001
BC033540-1|AAH33540.1| 730|Homo sapiens denticleless homolog (D... 44 0.001
BC033297-1|AAH33297.1| 730|Homo sapiens denticleless homolog (D... 44 0.001
BC021218-1|AAH21218.1| 559|Homo sapiens chromatin assembly fact... 44 0.001
AP001725-3|BAA95549.1| 559|Homo sapiens chromatin assembly fact... 44 0.001
AP000694-1|BAA89426.1| 559|Homo sapiens chromatin assembly fact... 44 0.001
AM177180-1|CAJ45484.1| 1670|Homo sapiens kinesin-like protein KI... 44 0.001
AL606468-1|CAH70697.1| 730|Homo sapiens denticleless homolog (D... 44 0.001
AL592297-1|CAH73803.1| 730|Homo sapiens denticleless homolog (D... 44 0.001
AL445252-3|CAI13644.1| 764|Homo sapiens transducin-like enhance... 44 0.001
AL358975-3|CAI13734.1| 764|Homo sapiens transducin-like enhance... 44 0.001
AL353813-5|CAI41315.1| 764|Homo sapiens transducin-like enhance... 44 0.001
AK027651-1|BAB55267.1| 211|Homo sapiens protein ( Homo sapiens ... 44 0.001
AK000076-1|BAA90929.1| 504|Homo sapiens protein ( Homo sapiens ... 44 0.001
AF345896-1|AAK54706.1| 730|Homo sapiens RA-regulated nuclear ma... 44 0.001
AF195765-1|AAF35182.1| 730|Homo sapiens L2DTL protein protein. 44 0.001
AB033087-1|BAA86575.1| 787|Homo sapiens KIAA1261 protein protein. 44 0.001
Z92544-1|CAM26347.1| 790|Homo sapiens WD repeat domain 24 protein. 44 0.002
M99435-1|AAA61192.1| 770|Homo sapiens transducin-like enhancer ... 44 0.002
BX538087-1|CAD98010.1| 913|Homo sapiens hypothetical protein pr... 44 0.002
BX537578-1|CAD97788.1| 913|Homo sapiens hypothetical protein pr... 44 0.002
BC139834-1|AAI39835.1| 415|Homo sapiens WDR32 protein protein. 44 0.002
BC108686-1|AAI08687.1| 412|Homo sapiens WDR32 protein protein. 44 0.002
BC068485-1|AAH68485.1| 383|Homo sapiens WD repeat domain 55 pro... 44 0.002
BC043247-1|AAH43247.1| 767|Homo sapiens TLE3 protein protein. 44 0.002
BC041831-1|AAH41831.1| 772|Homo sapiens TLE3 protein protein. 44 0.002
BC037168-1|AAH37168.1| 502|Homo sapiens WDR48 protein protein. 44 0.002
BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like ... 44 0.002
BC028697-1|AAH28697.3| 913|Homo sapiens WD repeat domain 44 pro... 44 0.002
BC022050-1|AAH22050.1| 551|Homo sapiens DMXL2 protein protein. 44 0.002
BC015747-1|AAH15747.1| 770|Homo sapiens transducin-like enhance... 44 0.002
BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein. 44 0.002
BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like ... 44 0.002
BC010100-1|AAH10100.1| 770|Homo sapiens transducin-like enhance... 44 0.002
BC009761-1|AAH09761.2| 718|Homo sapiens WDR24 protein protein. 44 0.002
BC008025-1|AAH08025.1| 790|Homo sapiens WD repeat domain 24 pro... 44 0.002
BC007620-1|AAH07620.1| 570|Homo sapiens TBL3 protein protein. 44 0.002
AY583460-1|AAS90946.1| 767|Homo sapiens transducin-like enhance... 44 0.002
AL834210-1|CAD38894.1| 805|Homo sapiens hypothetical protein pr... 44 0.002
AL391830-2|CAI41513.1| 905|Homo sapiens WD repeat domain 44 pro... 44 0.002
AL391830-1|CAI41512.1| 913|Homo sapiens WD repeat domain 44 pro... 44 0.002
AL391803-3|CAI41483.1| 905|Homo sapiens WD repeat domain 44 pro... 44 0.002
AL391803-2|CAI41482.1| 913|Homo sapiens WD repeat domain 44 pro... 44 0.002
AL391803-1|CAI41481.1| 805|Homo sapiens WD repeat domain 44 pro... 44 0.002
AL391474-2|CAI41403.1| 905|Homo sapiens WD repeat domain 44 pro... 44 0.002
AL391474-1|CAI41402.1| 913|Homo sapiens WD repeat domain 44 pro... 44 0.002
AL365190-2|CAI14977.1| 770|Homo sapiens transducin-like enhance... 44 0.002
AL353682-1|CAI12595.1| 770|Homo sapiens transducin-like enhance... 44 0.002
AL138752-6|CAI13878.1| 559|Homo sapiens WD repeat domain 32 pro... 44 0.002
AK127556-1|BAC87033.1| 429|Homo sapiens protein ( Homo sapiens ... 44 0.002
AK092077-1|BAC03799.1| 616|Homo sapiens protein ( Homo sapiens ... 44 0.002
AK025355-1|BAB15118.1| 383|Homo sapiens protein ( Homo sapiens ... 44 0.002
AF389880-1|AAL93215.1| 3036|Homo sapiens rabconnectin protein. 44 0.002
AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3 ... 44 0.002
AB046767-1|BAB13373.1| 863|Homo sapiens KIAA1547 protein protein. 44 0.002
AB020663-1|BAA74879.2| 2237|Homo sapiens KIAA0856 protein protein. 44 0.002
M95627-1|AAA68889.1| 452|Homo sapiens angio-associated migrator... 43 0.002
EF011617-1|ABK41107.1| 423|Homo sapiens CDW7/WDR12 protein. 43 0.002
DQ090887-1|AAY99645.1| 1196|Homo sapiens AHI1 protein. 43 0.002
CR456755-1|CAG33036.1| 452|Homo sapiens AAMP protein. 43 0.002
BT020045-1|AAV38848.1| 350|Homo sapiens unr-interacting protein... 43 0.002
BT020044-1|AAV38847.1| 350|Homo sapiens unr-interacting protein... 43 0.002
BC133025-1|AAI33026.1| 951|Homo sapiens WD repeat domain 36 pro... 43 0.002
BC117306-1|AAI17307.1| 698|Homo sapiens WD repeat domain 65 pro... 43 0.002
BC117280-1|AAI17281.1| 698|Homo sapiens WD repeat domain 65 pro... 43 0.002
BC062306-1|AAH62306.1| 350|Homo sapiens serine/threonine kinase... 43 0.002
BC039866-1|AAH39866.2| 434|Homo sapiens angio-associated, migra... 43 0.002
BC034964-1|AAH34964.1| 920|Homo sapiens WD repeat domain 47 pro... 43 0.002
BC027605-1|AAH27605.1| 660|Homo sapiens neural precursor cell e... 43 0.002
BC020799-1|AAH20799.1| 532|Homo sapiens Unknown (protein for IM... 43 0.002
BC020244-1|AAH20244.1| 429|Homo sapiens Similar to angio-associ... 43 0.002
>AK074217-1|BAB85020.1| 506|Homo sapiens protein ( Homo sapiens
cDNA FLJ23637 fis, clone CAS09287. ).
Length = 506
Score = 383 bits (942), Expect = e-105
Identities = 194/475 (40%), Positives = 287/475 (60%), Gaps = 9/475 (1%)
Query: 23 LTHDIIYWKKLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISK 82
+T D +YW PV +KEFGA+ +DFSP PY +A T S R+ +Y ++ K S+
Sbjct: 19 ITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSR 78
Query: 83 FVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKII 142
F + AY FR DGRLLVAG E+ V+LFD+ + LR F GHT VH T D+ ++
Sbjct: 79 FKDTAYCATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDSTADKYHVV 138
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S +DD +V LWDI + I F EH+DY+R G AS ++PD+ ++GSYDHTVK++D R++E
Sbjct: 139 SGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSE 198
Query: 203 TIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
++++V HG PVES L PSGG+ +SAGG +KVWD+ GG+LL ++ HHKTVT L L+S
Sbjct: 199 SVLSVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSS 258
Query: 263 NNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISIRKR 322
+ RL+S SLDR VK+Y +++KVVH+ D+ +ILS+A++ D+ + VGM +GI+S++ R
Sbjct: 259 SGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVVGMTNGILSVKHR 318
Query: 323 EEPVRQS----EKRKNLLKFIPDHTSQTKADTVEVANEVKINKKQKLPDCDVLIRKMQFS 378
+ ++ +R FI + D + + K K +L D D ++ + S
Sbjct: 319 KSEAKKESLPRRRRPAYRTFIKGKNYMKQRDDILINRPAK--KHLELYDRD--LKHFRIS 374
Query: 379 KALTVVLRPYISVKYPEKTTAVIQELLRREVLRVAIENLEEKFIGLLLKFLISKLGETRF 438
KAL VL P ++K PE T ++I+ L RR VL A+ +EK I +L FLI L + RF
Sbjct: 375 KALDRVLDPTCTIKTPEITVSIIKGLNRRGVLANALAGRDEKEISHVLNFLIRNLSQPRF 434
Query: 439 TRTIVDATNVFIDIFEGKINMFSPENLYLYKCLFKRVESEIKVCKSIAELEGAIN 493
+++A + IDI+ I SP + L VE EI + + E G ++
Sbjct: 435 APVLINAAEIIIDIYLPVIGQ-SPVVDKKFLLLQGLVEKEIDYQRELLETLGMMD 488
>BC013064-1|AAH13064.1| 285|Homo sapiens UTP15 protein protein.
Length = 285
Score = 154 bits (374), Expect = 6e-37
Identities = 93/264 (35%), Positives = 148/264 (56%), Gaps = 9/264 (3%)
Query: 238 IFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAIL 297
+ GG+LL ++ HHKTVT L L+S+ RL+S SLDR VK+Y +++KVVH+ D+ +IL
Sbjct: 1 MLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASIL 60
Query: 298 SMAISEHDDILTVGMMDGIISIRKREEPVRQS----EKRKNLLKFIPDHTSQTKADTVEV 353
S+A++ D+ + VGM +GI+S++ R+ ++ +R FI + D + +
Sbjct: 61 SLALAHEDETIVVGMTNGILSVKHRKSEAKKESLPRRRRPAYRTFIKGKNYMKQRDDILI 120
Query: 354 ANEVKINKKQKLPDCDVLIRKMQFSKALTVVLRPYISVKYPEKTTAVIQELLRREVLRVA 413
K K +L D D ++ + SKAL VL P ++K PE T ++I+EL RR VL A
Sbjct: 121 NRPAK--KHLELYDRD--LKHFRISKALDRVLDPTCTIKTPEITVSIIKELNRRGVLANA 176
Query: 414 IENLEEKFIGLLLKFLISKLGETRFTRTIVDATNVFIDIFEGKINMFSPENLYLYKCLFK 473
+ +EK I +L FLI L + RF +++A + IDI+ I SP + L
Sbjct: 177 LAGRDEKEISHVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQ-SPVVDKKFLLLQG 235
Query: 474 RVESEIKVCKSIAELEGAINLIMA 497
VE EI + + E G ++++ A
Sbjct: 236 LVEKEIDYQRELLETLGMMDMLFA 259
>AK022849-1|BAB14271.1| 285|Homo sapiens protein ( Homo sapiens
cDNA FLJ12787 fis, clone NT2RP2001943. ).
Length = 285
Score = 154 bits (374), Expect = 6e-37
Identities = 93/264 (35%), Positives = 148/264 (56%), Gaps = 9/264 (3%)
Query: 238 IFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAIL 297
+ GG+LL ++ HHKTVT L L+S+ RL+S SLDR VK+Y +++KVVH+ D+ +IL
Sbjct: 1 MLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASIL 60
Query: 298 SMAISEHDDILTVGMMDGIISIRKREEPVRQS----EKRKNLLKFIPDHTSQTKADTVEV 353
S+A++ D+ + VGM +GI+S++ R+ ++ +R FI + D + +
Sbjct: 61 SLALAHEDETIVVGMTNGILSVKHRKSEAKKESLPRRRRPAYRTFIKGKNYMKQRDDILI 120
Query: 354 ANEVKINKKQKLPDCDVLIRKMQFSKALTVVLRPYISVKYPEKTTAVIQELLRREVLRVA 413
K K +L D D ++ + SKAL VL P ++K PE T ++I+EL RR VL A
Sbjct: 121 NRPAK--KHLELYDRD--LKHFRISKALDRVLGPTCTIKTPEITVSIIKELNRRGVLANA 176
Query: 414 IENLEEKFIGLLLKFLISKLGETRFTRTIVDATNVFIDIFEGKINMFSPENLYLYKCLFK 473
+ +EK I +L FLI L + RF +++A + IDI+ I SP + L
Sbjct: 177 LAGRDEKEISHVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQ-SPVVDKKFLLLQG 235
Query: 474 RVESEIKVCKSIAELEGAINLIMA 497
VE EI + + E G ++++ A
Sbjct: 236 LVEKEIDYQRELLETLGMMDMLFA 259
>CR457295-1|CAG33576.1| 285|Homo sapiens FLJ12787 protein.
Length = 285
Score = 152 bits (369), Expect = 3e-36
Identities = 93/264 (35%), Positives = 147/264 (55%), Gaps = 9/264 (3%)
Query: 238 IFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAIL 297
+ GG+LL ++ HHKTVT L L+S+ RL+S SLDR VK+Y +++KVVH+ D+ +IL
Sbjct: 1 MLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASIL 60
Query: 298 SMAISEHDDILTVGMMDGIISIRKREEPVRQS----EKRKNLLKFIPDHTSQTKADTVEV 353
S+A++ D+ + VGM +GI S++ R+ ++ +R FI + D + +
Sbjct: 61 SLALAHEDETIVVGMTNGIPSVKHRKSEAKKESLPRRRRPAYRTFIKGKNYMKQRDDILI 120
Query: 354 ANEVKINKKQKLPDCDVLIRKMQFSKALTVVLRPYISVKYPEKTTAVIQELLRREVLRVA 413
K K +L D D ++ + SKAL VL P ++K PE T ++I+EL RR VL A
Sbjct: 121 NRPAK--KHLELYDRD--LKHFRISKALDRVLDPTCTIKTPEITVSIIKELNRRGVLANA 176
Query: 414 IENLEEKFIGLLLKFLISKLGETRFTRTIVDATNVFIDIFEGKINMFSPENLYLYKCLFK 473
+ +EK I +L FLI L + RF +++A + IDI+ I SP + L
Sbjct: 177 LAGRDEKEISHVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQ-SPVVDKKFLLLQG 235
Query: 474 RVESEIKVCKSIAELEGAINLIMA 497
VE EI + + E G ++++ A
Sbjct: 236 LVEKEIDYQRELLETLGMMDMLFA 259
>AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kDa
protein protein.
Length = 357
Score = 100 bits (240), Expect = 1e-20
Identities = 61/195 (31%), Positives = 96/195 (49%), Gaps = 3/195 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSK-NVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F +G L + + + L++V + GH+G V + D + S S DK+V
Sbjct: 74 FHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTV 133
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD T ER+ HT ++ + + SP ++ +GS D TVKL+D R I T +
Sbjct: 134 AVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDIRKKAAIQTFQNT 193
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V + F + IS G +IKVWD+ KL + H +VT L L+S S L+S
Sbjct: 194 YQVLAVTFNDTSDQIISGGIDNDIKVWDL-RQNKLTYTMRGHADSVTGLSLSSEGSYLLS 252
Query: 270 ASLDRHVKIYDVSTF 284
++D V+++DV F
Sbjct: 253 NAMDNTVRVWDVRPF 267
Score = 47.2 bits (107), Expect = 1e-04
Identities = 39/206 (18%), Positives = 86/206 (41%), Gaps = 8/206 (3%)
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTE-ERIANFNEHTDYIRAGAAS 177
+ + +GH G V+ F + + S D+ + LW++ + + A H+ +
Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVME-LHY 117
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE--IK 234
++ S S D TV ++D + E + + H S V S + G + +K
Sbjct: 118 NTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVK 177
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFP 293
+WDI K Q+ V + + +++S +D +K++D+ K+ + +
Sbjct: 178 LWDIRK--KAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHA 235
Query: 294 NAILSMAISEHDDILTVGMMDGIISI 319
+++ +++S L MD + +
Sbjct: 236 DSVTGLSLSSEGSYLLSNAMDNTVRV 261
Score = 41.9 bits (94), Expect = 0.005
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 74 KVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTF 133
K+ N+ F + + DG + AG + V ++D S+ +L GH G ++
Sbjct: 275 KIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVA 334
Query: 134 FTKDQLKIISYSDDKSVGLWDI 155
F D+ IIS S DK + + +I
Sbjct: 335 FHPDEPIIISASSDKRLYMGEI 356
>EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein.
Length = 357
Score = 99.1 bits (236), Expect = 3e-20
Identities = 60/195 (30%), Positives = 95/195 (48%), Gaps = 3/195 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSK-NVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F +G L + + + L++V + GH+G V + D + S S DK+V
Sbjct: 74 FHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTV 133
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD T ER+ HT ++ + + P ++ +GS D TVKL+D R I T +
Sbjct: 134 AVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNT 193
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V + F + IS G +IKVWD+ KL + H +VT L L+S S L+S
Sbjct: 194 YQVLAVTFNDTSDQIISGGIDNDIKVWDL-RQNKLTYTMRGHADSVTGLSLSSEGSYLLS 252
Query: 270 ASLDRHVKIYDVSTF 284
++D V+++DV F
Sbjct: 253 NAMDNTVRVWDVRPF 267
Score = 49.2 bits (112), Expect = 4e-05
Identities = 40/206 (19%), Positives = 87/206 (42%), Gaps = 8/206 (3%)
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTE-ERIANFNEHTDYIRAGAAS 177
+ + +GH G V+ F + + S D+ + LW++ + + A H+ +
Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVME-LHY 117
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE--IK 234
++ S S D TV ++D + E + + H S V S G + G + +K
Sbjct: 118 NTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVK 177
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFP 293
+WDI K Q+ V + + +++S +D +K++D+ K+ + +
Sbjct: 178 LWDIRK--KAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHA 235
Query: 294 NAILSMAISEHDDILTVGMMDGIISI 319
+++ +++S L MD + +
Sbjct: 236 DSVTGLSLSSEGSYLLSNAMDNTVRV 261
Score = 41.9 bits (94), Expect = 0.005
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 74 KVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTF 133
K+ N+ F + + DG + AG + V ++D S+ +L GH G ++
Sbjct: 275 KIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVA 334
Query: 134 FTKDQLKIISYSDDKSVGLWDI 155
F D+ IIS S DK + + +I
Sbjct: 335 FHPDEPIIISASSDKRLYMGEI 356
>BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 99.1 bits (236), Expect = 3e-20
Identities = 60/195 (30%), Positives = 95/195 (48%), Gaps = 3/195 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSK-NVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F +G L + + + L++V + GH+G V + D + S S DK+V
Sbjct: 74 FHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTV 133
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD T ER+ HT ++ + + P ++ +GS D TVKL+D R I T +
Sbjct: 134 AVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNT 193
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V + F + IS G +IKVWD+ KL + H +VT L L+S S L+S
Sbjct: 194 YQVLAVTFNDTSDQIISGGIDNDIKVWDL-RQNKLTYTMRGHADSVTGLSLSSEGSYLLS 252
Query: 270 ASLDRHVKIYDVSTF 284
++D V+++DV F
Sbjct: 253 NAMDNTVRVWDVRPF 267
Score = 49.2 bits (112), Expect = 4e-05
Identities = 40/206 (19%), Positives = 87/206 (42%), Gaps = 8/206 (3%)
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTE-ERIANFNEHTDYIRAGAAS 177
+ + +GH G V+ F + + S D+ + LW++ + + A H+ +
Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVME-LHY 117
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE--IK 234
++ S S D TV ++D + E + + H S V S G + G + +K
Sbjct: 118 NTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVK 177
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFP 293
+WDI K Q+ V + + +++S +D +K++D+ K+ + +
Sbjct: 178 LWDIRK--KAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHA 235
Query: 294 NAILSMAISEHDDILTVGMMDGIISI 319
+++ +++S L MD + +
Sbjct: 236 DSVTGLSLSSEGSYLLSNAMDNTVRV 261
Score = 41.9 bits (94), Expect = 0.005
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 74 KVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTF 133
K+ N+ F + + DG + AG + V ++D S+ +L GH G ++
Sbjct: 275 KIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVA 334
Query: 134 FTKDQLKIISYSDDKSVGLWDI 155
F D+ IIS S DK + + +I
Sbjct: 335 FHPDEPIIISASSDKRLYMGEI 356
>AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 99.1 bits (236), Expect = 3e-20
Identities = 60/195 (30%), Positives = 95/195 (48%), Gaps = 3/195 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSK-NVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F +G L + + + L++V + GH+G V + D + S S DK+V
Sbjct: 74 FHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTV 133
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD T ER+ HT ++ + + P ++ +GS D TVKL+D R I T +
Sbjct: 134 AVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNT 193
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V + F + IS G +IKVWD+ KL + H +VT L L+S S L+S
Sbjct: 194 YQVLAVTFNDTSDQIISGGIDNDIKVWDL-RQNKLTYTMRGHADSVTGLSLSSEGSYLLS 252
Query: 270 ASLDRHVKIYDVSTF 284
++D V+++DV F
Sbjct: 253 NAMDNTVRVWDVRPF 267
Score = 49.2 bits (112), Expect = 4e-05
Identities = 40/206 (19%), Positives = 87/206 (42%), Gaps = 8/206 (3%)
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTE-ERIANFNEHTDYIRAGAAS 177
+ + +GH G V+ F + + S D+ + LW++ + + A H+ +
Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVME-LHY 117
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE--IK 234
++ S S D TV ++D + E + + H S V S G + G + +K
Sbjct: 118 NTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVK 177
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFP 293
+WDI K Q+ V + + +++S +D +K++D+ K+ + +
Sbjct: 178 LWDIRK--KAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHA 235
Query: 294 NAILSMAISEHDDILTVGMMDGIISI 319
+++ +++S L MD + +
Sbjct: 236 DSVTGLSLSSEGSYLLSNAMDNTVRV 261
Score = 41.9 bits (94), Expect = 0.005
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 74 KVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTF 133
K+ N+ F + + DG + AG + V ++D S+ +L GH G ++
Sbjct: 275 KIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVA 334
Query: 134 FTKDQLKIISYSDDKSVGLWDI 155
F D+ IIS S DK + + +I
Sbjct: 335 FHPDEPIIISASSDKRLYMGEI 356
>AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor
protein.
Length = 310
Score = 98.7 bits (235), Expect = 4e-20
Identities = 59/195 (30%), Positives = 95/195 (48%), Gaps = 3/195 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSK-NVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F +G L + + + L++V + GH+G V + D + S S DK+V
Sbjct: 15 FHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTV 74
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD T ER+ HT ++ + + P ++ +GS D TVKL+D R + T +
Sbjct: 75 AVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNT 134
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V + F + IS G +IKVWD+ KL + H +VT L L+S S L+S
Sbjct: 135 YQVLAVTFNDTSDQIISGGIDNDIKVWDL-RQNKLTYTMRGHADSVTGLSLSSEGSYLLS 193
Query: 270 ASLDRHVKIYDVSTF 284
++D V+++DV F
Sbjct: 194 NAMDNTVRVWDVRPF 208
Score = 48.8 bits (111), Expect = 5e-05
Identities = 40/204 (19%), Positives = 86/204 (42%), Gaps = 8/204 (3%)
Query: 121 VFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTE-ERIANFNEHTDYIRAGAASPI 179
+ +GH G V+ F + + S D+ + LW++ + + A H+ +
Sbjct: 2 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVME-LHYNT 60
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE--IKVW 236
++ S S D TV ++D + E + + H S V S G + G + +K+W
Sbjct: 61 DGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLW 120
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPNA 295
DI K Q+ V + + +++S +D +K++D+ K+ + + ++
Sbjct: 121 DIRK--KAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADS 178
Query: 296 ILSMAISEHDDILTVGMMDGIISI 319
+ +++S L MD + +
Sbjct: 179 VTGLSLSSEGSYLLSNAMDNTVRV 202
>BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein.
Length = 441
Score = 96.3 bits (229), Expect = 2e-19
Identities = 60/201 (29%), Positives = 99/201 (49%), Gaps = 4/201 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G LL +G + V+++ K VF HT V F D ++ SDDK+V
Sbjct: 103 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVK 162
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT-VNHG 210
+W ++ + + ++H +++R SP +I+S S D TVKL+D S E + + HG
Sbjct: 163 VWATHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKSSRECVHSYCEHG 221
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V F PSG +AG +KVWD+ +LL + H V L + + L++
Sbjct: 222 GFVTYVDFHPSGTCIAAAGMDNTVKVWDV-RTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 280
Query: 270 ASLDRHVKIYDVSTFKVVHNI 290
AS D +KI D+ ++++ +
Sbjct: 281 ASSDSTLKILDLMEGRLLYTL 301
Score = 86.2 bits (204), Expect = 3e-16
Identities = 79/335 (23%), Positives = 141/335 (42%), Gaps = 13/335 (3%)
Query: 44 AIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGI 103
A+ ++FSP + + V+++ P K + F +DG+ V
Sbjct: 97 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTAS 156
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ VK++ + L + H V F+ D I+S SDDK+V LWD S+ E + +
Sbjct: 157 DDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 216
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSG 222
+ EH ++ P S I + D+TVK++D R++ + H + V F PSG
Sbjct: 217 YCEHGGFVTYVDFHP-SGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSG 275
Query: 223 GIFISAGG-TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKI--- 278
I+A + +K+ D+ G +LL + H TT+ + S D V +
Sbjct: 276 NYLITASSDSTLKILDLMEG-RLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 334
Query: 279 -YDVSTFKVVHNIDFPNAILSMA---ISEHDDILTVGMMDGIISIRKR-EEPVRQSEKRK 333
+D+ V + P A L+ + + E D + G + S++ + +EPV +
Sbjct: 335 NFDIVDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLT 394
Query: 334 NLLKFIPDHTSQTKADTVEVANEVKINKKQKLPDC 368
+ L+ I TV + + + KL C
Sbjct: 395 STLEHIVGQL-DVLTQTVSILEQRLTLTEDKLKQC 428
Score = 70.9 bits (166), Expect = 1e-11
Identities = 50/173 (28%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R F GH V F+ + ++ S S D + +W + + R F H D + SP
Sbjct: 47 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP- 105
Query: 180 SPDIILSGSYDHTVKLY--DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE-IKVW 236
S ++ SGS D TV+++ + + T+ H + V S F G F++A + +KVW
Sbjct: 106 SGHLLASGSRDKTVRIWVPNVKGESTVFRA-HTATVRSVHFCSDGQSFVTASDDKTVKVW 164
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHN 289
+ K L ++SQH V + + + ++SAS D+ VK++D S+ + VH+
Sbjct: 165 -ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 216
Score = 60.9 bits (141), Expect = 1e-08
Identities = 45/209 (21%), Positives = 100/209 (47%), Gaps = 4/209 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + L +G ++ + ++ ++ ++ FTGH V F+ + S S DK+V
Sbjct: 61 FSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR 120
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HG 210
+W + + F HT +R+ + + S D TVK++ + + +++ H
Sbjct: 121 IWVPNVKGESTVFRAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFSLSQHI 179
Query: 211 SPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V F P G + +SA + +K+WD + + + + +H VT + + + + +
Sbjct: 180 NWVRCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAA 238
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILS 298
A +D VK++DV T +++ + +A ++
Sbjct: 239 AGMDNTVKVWDVRTHRLLQHYQLHSAAVN 267
Score = 47.6 bits (108), Expect = 1e-04
Identities = 28/111 (25%), Positives = 46/111 (41%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + Y+DF P AA V+V+D T + ++ A G F G L+
Sbjct: 222 GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITA 281
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
++ +K+ D+ +L GH GP F++ S D+ V +W
Sbjct: 282 SSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 332
>BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A
protein.
Length = 407
Score = 96.3 bits (229), Expect = 2e-19
Identities = 60/201 (29%), Positives = 99/201 (49%), Gaps = 4/201 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G LL +G + V+++ K VF HT V F D ++ SDDK+V
Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVK 128
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT-VNHG 210
+W ++ + + ++H +++R SP +I+S S D TVKL+D S E + + HG
Sbjct: 129 VWATHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKSSRECVHSYCEHG 187
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V F PSG +AG +KVWD+ +LL + H V L + + L++
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWDV-RTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 246
Query: 270 ASLDRHVKIYDVSTFKVVHNI 290
AS D +KI D+ ++++ +
Sbjct: 247 ASSDSTLKILDLMEGRLLYTL 267
Score = 86.2 bits (204), Expect = 3e-16
Identities = 79/335 (23%), Positives = 141/335 (42%), Gaps = 13/335 (3%)
Query: 44 AIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGI 103
A+ ++FSP + + V+++ P K + F +DG+ V
Sbjct: 63 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTAS 122
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ VK++ + L + H V F+ D I+S SDDK+V LWD S+ E + +
Sbjct: 123 DDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 182
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSG 222
+ EH ++ P S I + D+TVK++D R++ + H + V F PSG
Sbjct: 183 YCEHGGFVTYVDFHP-SGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSG 241
Query: 223 GIFISAGG-TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKI--- 278
I+A + +K+ D+ G +LL + H TT+ + S D V +
Sbjct: 242 NYLITASSDSTLKILDLMEG-RLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
Query: 279 -YDVSTFKVVHNIDFPNAILSMA---ISEHDDILTVGMMDGIISIRKR-EEPVRQSEKRK 333
+D+ V + P A L+ + + E D + G + S++ + +EPV +
Sbjct: 301 NFDIVDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLT 360
Query: 334 NLLKFIPDHTSQTKADTVEVANEVKINKKQKLPDC 368
+ L+ I TV + + + KL C
Sbjct: 361 STLEHIVGQL-DVLTQTVSILEQRLTLTEDKLKQC 394
Score = 70.9 bits (166), Expect = 1e-11
Identities = 50/173 (28%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R F GH V F+ + ++ S S D + +W + + R F H D + SP
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP- 71
Query: 180 SPDIILSGSYDHTVKLY--DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE-IKVW 236
S ++ SGS D TV+++ + + T+ H + V S F G F++A + +KVW
Sbjct: 72 SGHLLASGSRDKTVRIWVPNVKGESTVFRA-HTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHN 289
+ K L ++SQH V + + + ++SAS D+ VK++D S+ + VH+
Sbjct: 131 -ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 182
Score = 60.9 bits (141), Expect = 1e-08
Identities = 45/209 (21%), Positives = 100/209 (47%), Gaps = 4/209 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + L +G ++ + ++ ++ ++ FTGH V F+ + S S DK+V
Sbjct: 27 FSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR 86
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HG 210
+W + + F HT +R+ + + S D TVK++ + + +++ H
Sbjct: 87 IWVPNVKGESTVFRAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFSLSQHI 145
Query: 211 SPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V F P G + +SA + +K+WD + + + + +H VT + + + + +
Sbjct: 146 NWVRCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAA 204
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILS 298
A +D VK++DV T +++ + +A ++
Sbjct: 205 AGMDNTVKVWDVRTHRLLQHYQLHSAAVN 233
Score = 47.6 bits (108), Expect = 1e-04
Identities = 28/111 (25%), Positives = 46/111 (41%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + Y+DF P AA V+V+D T + ++ A G F G L+
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITA 247
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
++ +K+ D+ +L GH GP F++ S D+ V +W
Sbjct: 248 SSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
>BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein.
Length = 359
Score = 96.3 bits (229), Expect = 2e-19
Identities = 60/201 (29%), Positives = 99/201 (49%), Gaps = 4/201 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G LL +G + V+++ K VF HT V F D ++ SDDK+V
Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVK 128
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT-VNHG 210
+W ++ + + ++H +++R SP +I+S S D TVKL+D S E + + HG
Sbjct: 129 VWATHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKSSRECVHSYCEHG 187
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V F PSG +AG +KVWD+ +LL + H V L + + L++
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWDV-RTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 246
Query: 270 ASLDRHVKIYDVSTFKVVHNI 290
AS D +KI D+ ++++ +
Sbjct: 247 ASSDSTLKILDLMEGRLLYTL 267
Score = 85.4 bits (202), Expect = 4e-16
Identities = 71/299 (23%), Positives = 133/299 (44%), Gaps = 14/299 (4%)
Query: 44 AIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGI 103
A+ ++FSP + + V+++ P K + F +DG+ V
Sbjct: 63 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTAS 122
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ VK++ + L + H V F+ D I+S SDDK+V LWD S+ E + +
Sbjct: 123 DDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 182
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSG 222
+ EH ++ P S I + D+TVK++D R++ + H + V F PSG
Sbjct: 183 YCEHGGFVTYVDFHP-SGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSG 241
Query: 223 GIFISAGG-TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKI--- 278
I+A + +K+ D+ G +LL + H TT+ + S D V +
Sbjct: 242 NYLITASSDSTLKILDLMEG-RLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
Query: 279 -YDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISIRKREEPVRQSEKRKNLL 336
+D+ V + P A L+ ++ LTV +++ +++ E+ ++Q + + L+
Sbjct: 301 NFDIVDHGEVTKVPRPPATLASSMGN----LTVSILEQRLTL--TEDKLKQCLENQQLI 353
Score = 70.9 bits (166), Expect = 1e-11
Identities = 50/173 (28%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R F GH V F+ + ++ S S D + +W + + R F H D + SP
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP- 71
Query: 180 SPDIILSGSYDHTVKLY--DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE-IKVW 236
S ++ SGS D TV+++ + + T+ H + V S F G F++A + +KVW
Sbjct: 72 SGHLLASGSRDKTVRIWVPNVKGESTVFRA-HTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHN 289
+ K L ++SQH V + + + ++SAS D+ VK++D S+ + VH+
Sbjct: 131 -ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 182
Score = 60.9 bits (141), Expect = 1e-08
Identities = 45/209 (21%), Positives = 100/209 (47%), Gaps = 4/209 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + L +G ++ + ++ ++ ++ FTGH V F+ + S S DK+V
Sbjct: 27 FSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR 86
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HG 210
+W + + F HT +R+ + + S D TVK++ + + +++ H
Sbjct: 87 IWVPNVKGESTVFRAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFSLSQHI 145
Query: 211 SPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V F P G + +SA + +K+WD + + + + +H VT + + + + +
Sbjct: 146 NWVRCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAA 204
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILS 298
A +D VK++DV T +++ + +A ++
Sbjct: 205 AGMDNTVKVWDVRTHRLLQHYQLHSAAVN 233
Score = 47.6 bits (108), Expect = 1e-04
Identities = 28/111 (25%), Positives = 46/111 (41%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + Y+DF P AA V+V+D T + ++ A G F G L+
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITA 247
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
++ +K+ D+ +L GH GP F++ S D+ V +W
Sbjct: 248 SSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
>BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein.
Length = 396
Score = 96.3 bits (229), Expect = 2e-19
Identities = 60/201 (29%), Positives = 99/201 (49%), Gaps = 4/201 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G LL +G + V+++ K VF HT V F D ++ SDDK+V
Sbjct: 58 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVK 117
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT-VNHG 210
+W ++ + + ++H +++R SP +I+S S D TVKL+D S E + + HG
Sbjct: 118 VWATHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKSSRECVHSYCEHG 176
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V F PSG +AG +KVWD+ +LL + H V L + + L++
Sbjct: 177 GFVTYVDFHPSGTCIAAAGMDNTVKVWDV-RTHRLLQHYQLHSAAVNGLSFHPSGNYLIT 235
Query: 270 ASLDRHVKIYDVSTFKVVHNI 290
AS D +KI D+ ++++ +
Sbjct: 236 ASSDSTLKILDLMEGRLLYTL 256
Score = 86.2 bits (204), Expect = 3e-16
Identities = 79/335 (23%), Positives = 141/335 (42%), Gaps = 13/335 (3%)
Query: 44 AIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGI 103
A+ ++FSP + + V+++ P K + F +DG+ V
Sbjct: 52 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTAS 111
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ VK++ + L + H V F+ D I+S SDDK+V LWD S+ E + +
Sbjct: 112 DDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 171
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSG 222
+ EH ++ P S I + D+TVK++D R++ + H + V F PSG
Sbjct: 172 YCEHGGFVTYVDFHP-SGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSG 230
Query: 223 GIFISAGG-TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKI--- 278
I+A + +K+ D+ G +LL + H TT+ + S D V +
Sbjct: 231 NYLITASSDSTLKILDLMEG-RLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 289
Query: 279 -YDVSTFKVVHNIDFPNAILSMA---ISEHDDILTVGMMDGIISIRKR-EEPVRQSEKRK 333
+D+ V + P A L+ + + E D + G + S++ + +EPV +
Sbjct: 290 NFDIVDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLT 349
Query: 334 NLLKFIPDHTSQTKADTVEVANEVKINKKQKLPDC 368
+ L+ I TV + + + KL C
Sbjct: 350 STLEHIVGQL-DVLTQTVSILEQRLTLTEDKLKQC 383
Score = 70.9 bits (166), Expect = 1e-11
Identities = 50/173 (28%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R F GH V F+ + ++ S S D + +W + + R F H D + SP
Sbjct: 2 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP- 60
Query: 180 SPDIILSGSYDHTVKLY--DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE-IKVW 236
S ++ SGS D TV+++ + + T+ H + V S F G F++A + +KVW
Sbjct: 61 SGHLLASGSRDKTVRIWVPNVKGESTVFRA-HTATVRSVHFCSDGQSFVTASDDKTVKVW 119
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHN 289
+ K L ++SQH V + + + ++SAS D+ VK++D S+ + VH+
Sbjct: 120 -ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 171
Score = 60.9 bits (141), Expect = 1e-08
Identities = 45/209 (21%), Positives = 100/209 (47%), Gaps = 4/209 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + L +G ++ + ++ ++ ++ FTGH V F+ + S S DK+V
Sbjct: 16 FSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR 75
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HG 210
+W + + F HT +R+ + + S D TVK++ + + +++ H
Sbjct: 76 IWVPNVKGESTVFRAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFSLSQHI 134
Query: 211 SPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V F P G + +SA + +K+WD + + + + +H VT + + + + +
Sbjct: 135 NWVRCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAA 193
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILS 298
A +D VK++DV T +++ + +A ++
Sbjct: 194 AGMDNTVKVWDVRTHRLLQHYQLHSAAVN 222
Score = 47.6 bits (108), Expect = 1e-04
Identities = 28/111 (25%), Positives = 46/111 (41%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + Y+DF P AA V+V+D T + ++ A G F G L+
Sbjct: 177 GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITA 236
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
++ +K+ D+ +L GH GP F++ S D+ V +W
Sbjct: 237 SSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 287
>AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens
cDNA FLJ90808 fis, clone Y79AA1000777, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 407
Score = 95.9 bits (228), Expect = 3e-19
Identities = 60/201 (29%), Positives = 99/201 (49%), Gaps = 4/201 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G LL +G + V+++ K VF HT V F D ++ SDDK+V
Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVK 128
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT-VNHG 210
+W ++ + + ++H +++R SP +I+S S D TVKL+D S E + + HG
Sbjct: 129 VWATHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKSSRECVHSYCEHG 187
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V F PSG +AG +KVWD+ +LL + H V L + + L++
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWDV-RTYRLLQHYQLHSAAVNGLSFHPSGNYLIT 246
Query: 270 ASLDRHVKIYDVSTFKVVHNI 290
AS D +KI D+ ++++ +
Sbjct: 247 ASSDSTLKILDLMEGRLLYTL 267
Score = 85.0 bits (201), Expect = 6e-16
Identities = 79/335 (23%), Positives = 140/335 (41%), Gaps = 13/335 (3%)
Query: 44 AIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGI 103
A+ ++FSP + + V+++ P K + F +DG+ V
Sbjct: 63 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTAS 122
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ VK++ + L + H V F+ D I+S SDDK+V LWD S+ E + +
Sbjct: 123 DDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 182
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSG 222
+ EH ++ P S I + D+TVK++D R+ + H + V F PSG
Sbjct: 183 YCEHGGFVTYVDFHP-SGTCIAAAGMDNTVKVWDVRTYRLLQHYQLHSAAVNGLSFHPSG 241
Query: 223 GIFISAGG-TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKI--- 278
I+A + +K+ D+ G +LL + H TT+ + S D V +
Sbjct: 242 NYLITASSDSTLKILDLMEG-RLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
Query: 279 -YDVSTFKVVHNIDFPNAILSMA---ISEHDDILTVGMMDGIISIRKR-EEPVRQSEKRK 333
+D+ V + P A L+ + + E D + G + S++ + +EPV +
Sbjct: 301 NFDIVDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLT 360
Query: 334 NLLKFIPDHTSQTKADTVEVANEVKINKKQKLPDC 368
+ L+ I TV + + + KL C
Sbjct: 361 STLEHIVGQL-DVLTQTVSILEQRLTLTEDKLKQC 394
Score = 70.9 bits (166), Expect = 1e-11
Identities = 50/173 (28%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R F GH V F+ + ++ S S D + +W + + R F H D + SP
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP- 71
Query: 180 SPDIILSGSYDHTVKLY--DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE-IKVW 236
S ++ SGS D TV+++ + + T+ H + V S F G F++A + +KVW
Sbjct: 72 SGHLLASGSRDKTVRIWVPNVKGESTVFRA-HTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHN 289
+ K L ++SQH V + + + ++SAS D+ VK++D S+ + VH+
Sbjct: 131 -ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 182
Score = 62.5 bits (145), Expect = 4e-09
Identities = 45/209 (21%), Positives = 101/209 (48%), Gaps = 4/209 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + L +G ++ + ++ ++ ++ FTGH V F+ + S S DK+V
Sbjct: 27 FSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR 86
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HG 210
+W + + F HT +R+ + + S D TVK++ + + +++ H
Sbjct: 87 IWVPNVKGESTVFRAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFSLSQHI 145
Query: 211 SPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V F P G + +SA + +K+WD + + + + +H VT + + + + +
Sbjct: 146 NWVRCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAA 204
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILS 298
A +D VK++DV T++++ + +A ++
Sbjct: 205 AGMDNTVKVWDVRTYRLLQHYQLHSAAVN 233
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/111 (25%), Positives = 46/111 (41%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + Y+DF P AA V+V+D T + ++ A G F G L+
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQHYQLHSAAVNGLSFHPSGNYLITA 247
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
++ +K+ D+ +L GH GP F++ S D+ V +W
Sbjct: 248 SSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
>CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein.
Length = 655
Score = 94.3 bits (224), Expect = 1e-18
Identities = 62/227 (27%), Positives = 98/227 (43%), Gaps = 5/227 (2%)
Query: 93 RADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
+A GRLL G ++ V L+ + N + TGHT PV + I++ S S+ +
Sbjct: 30 KASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRV 89
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGS 211
WD+ + + H I + P + + SGS D +KL+D R + H
Sbjct: 90 WDLEAAKILRTLMGHKANICSLDFHPYG-EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQ 148
Query: 212 PVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
V F P G SA +K+WD+ GK++S H V + N L S
Sbjct: 149 AVRCLRFSPDGKWLASAADDHTVKLWDL-TAGKMMSEFPGHTGPVNVVEFHPNEYLLASG 207
Query: 271 SLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGI 316
S DR ++ +D+ F+VV I+ P + S+ + L G D +
Sbjct: 208 SSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSL 254
Score = 68.9 bits (161), Expect = 4e-11
Identities = 38/146 (26%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G + +G ++ +KL+D++ K + + GH+ V F+ D + S +DD +V
Sbjct: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVK 172
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
LWD++ + ++ F HT + P + ++ SGS D T++ +D + + +
Sbjct: 173 LWDLTAGKMMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFWDLEKFQVVSCIEGEP 231
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVW 236
PV S LF P G S ++V+
Sbjct: 232 GPVRSVLFNPDGCCLYSGCQDSLRVY 257
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/108 (25%), Positives = 53/108 (49%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
LDF P + + + ++++D K +A F DG+ L + ++
Sbjct: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
VKL+D+ + ++ F GHTGPV+ F ++ + S S D+++ WD+
Sbjct: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
>BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80
(WD40-containing) subunit B 1 protein.
Length = 655
Score = 94.3 bits (224), Expect = 1e-18
Identities = 62/227 (27%), Positives = 98/227 (43%), Gaps = 5/227 (2%)
Query: 93 RADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
+A GRLL G ++ V L+ + N + TGHT PV + I++ S S+ +
Sbjct: 30 KASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRV 89
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGS 211
WD+ + + H I + P + + SGS D +KL+D R + H
Sbjct: 90 WDLEAAKILRTLMGHKANICSLDFHPYG-EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQ 148
Query: 212 PVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
V F P G SA +K+WD+ GK++S H V + N L S
Sbjct: 149 AVRCLRFSPDGKWLASAADDHTVKLWDL-TAGKMMSEFPGHTGPVNVVEFHPNEYLLASG 207
Query: 271 SLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGI 316
S DR ++ +D+ F+VV I+ P + S+ + L G D +
Sbjct: 208 SSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSL 254
Score = 68.9 bits (161), Expect = 4e-11
Identities = 38/146 (26%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G + +G ++ +KL+D++ K + + GH+ V F+ D + S +DD +V
Sbjct: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVK 172
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
LWD++ + ++ F HT + P + ++ SGS D T++ +D + + +
Sbjct: 173 LWDLTAGKMMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFWDLEKFQVVSCIEGEP 231
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVW 236
PV S LF P G S ++V+
Sbjct: 232 GPVRSVLFNPDGCCLYSGCQDSLRVY 257
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/108 (25%), Positives = 53/108 (49%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
LDF P + + + ++++D K +A F DG+ L + ++
Sbjct: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
VKL+D+ + ++ F GHTGPV+ F ++ + S S D+++ WD+
Sbjct: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
>BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat
containing) subunit B 1 protein.
Length = 655
Score = 94.3 bits (224), Expect = 1e-18
Identities = 62/227 (27%), Positives = 98/227 (43%), Gaps = 5/227 (2%)
Query: 93 RADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
+A GRLL G ++ V L+ + N + TGHT PV + I++ S S+ +
Sbjct: 30 KASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRV 89
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGS 211
WD+ + + H I + P + + SGS D +KL+D R + H
Sbjct: 90 WDLEAAKILRTLMGHKANICSLDFHPYG-EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQ 148
Query: 212 PVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
V F P G SA +K+WD+ GK++S H V + N L S
Sbjct: 149 AVRCLRFSPDGKWLASAADDHTVKLWDL-TAGKMMSEFPGHTGPVNVVEFHPNEYLLASG 207
Query: 271 SLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGI 316
S DR ++ +D+ F+VV I+ P + S+ + L G D +
Sbjct: 208 SSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSL 254
Score = 68.9 bits (161), Expect = 4e-11
Identities = 38/146 (26%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G + +G ++ +KL+D++ K + + GH+ V F+ D + S +DD +V
Sbjct: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVK 172
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
LWD++ + ++ F HT + P + ++ SGS D T++ +D + + +
Sbjct: 173 LWDLTAGKMMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFWDLEKFQVVSCIEGEP 231
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVW 236
PV S LF P G S ++V+
Sbjct: 232 GPVRSVLFNPDGCCLYSGCQDSLRVY 257
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/108 (25%), Positives = 53/108 (49%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
LDF P + + + ++++D K +A F DG+ L + ++
Sbjct: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
VKL+D+ + ++ F GHTGPV+ F ++ + S S D+++ WD+
Sbjct: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
>CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein.
Length = 330
Score = 91.9 bits (218), Expect = 5e-18
Identities = 48/200 (24%), Positives = 105/200 (52%), Gaps = 3/200 (1%)
Query: 85 EAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISY 144
EA F +G L + + + ++ + GH + ++ D +++S
Sbjct: 42 EAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSA 101
Query: 145 SDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI 204
SDDK++ LWD+ + + + H++Y+ +P S ++I+SGS+D TVK+++ ++ + +
Sbjct: 102 SDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPS-NLIISGSFDETVKIWEVKTGKCL 160
Query: 205 MTVN-HGSPVESTLFLPSGGIFISAGGTEI-KVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
T++ H PV + F SG + +S + ++WD +G L + + + V+ ++ +
Sbjct: 161 KTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSP 220
Query: 263 NNSRLMSASLDRHVKIYDVS 282
N +++A+LD +K++D S
Sbjct: 221 NGKYILTATLDNTLKLWDYS 240
Score = 80.2 bits (189), Expect = 2e-14
Identities = 57/234 (24%), Positives = 115/234 (49%), Gaps = 9/234 (3%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+D LV+ ++ +KL+DV+S L+ GH+ V F IIS S D++V +W
Sbjct: 93 SDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIW 152
Query: 154 DISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--NHGS 211
++ T + + + H+D + A S +I+SGSYD +++D S + + T+ +
Sbjct: 153 EVKTGKCLKTLSAHSDPVSA-VHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNP 211
Query: 212 PVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQH--HKTVTTLRLASNNSR-L 267
PV F P+G ++A +K+WD ++ G+ L + H K + + +
Sbjct: 212 PVSFVKFSPNGKYILTATLDNTLKLWD-YSRGRCLKTYTGHKNEKYCIFANFSVTGGKWI 270
Query: 268 MSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISIR 320
+S S D V I+++ T ++V + + ++S A ++++ ++ +I+
Sbjct: 271 VSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIK 324
Score = 49.2 bits (112), Expect = 4e-05
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGP---VHRTFFTKDQLKIISYSDDK 148
F +G+ ++ + +KL+D L+ +TGH + F I+S S+D
Sbjct: 218 FSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDN 277
Query: 149 SVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSY--DHTVKLY 196
V +W++ T+E + HTD + + A P + ++I S + D T+KL+
Sbjct: 278 LVYIWNLQTKEIVQKLQGHTDVVISAACHP-TENLIASAALENDKTIKLW 326
Score = 44.4 bits (100), Expect = 0.001
Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
V H V S F P+G S+ I +W ++G K + H+ ++ + +S++S
Sbjct: 38 VGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDG-KYEKTLYGHNLEISDVAWSSDSS 96
Query: 266 RLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
RL+SAS D+ +K++DV + K + + N + + +++ G D + I
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKI 151
>BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B
protein.
Length = 330
Score = 91.9 bits (218), Expect = 5e-18
Identities = 48/200 (24%), Positives = 105/200 (52%), Gaps = 3/200 (1%)
Query: 85 EAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISY 144
EA F +G L + + + ++ + GH + ++ D +++S
Sbjct: 42 EAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSA 101
Query: 145 SDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI 204
SDDK++ LWD+ + + + H++Y+ +P S ++I+SGS+D TVK+++ ++ + +
Sbjct: 102 SDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPS-NLIISGSFDETVKIWEVKTGKCL 160
Query: 205 MTVN-HGSPVESTLFLPSGGIFISAGGTEI-KVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
T++ H PV + F SG + +S + ++WD +G L + + + V+ ++ +
Sbjct: 161 KTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSP 220
Query: 263 NNSRLMSASLDRHVKIYDVS 282
N +++A+LD +K++D S
Sbjct: 221 NGKYILTATLDNTLKLWDYS 240
Score = 80.2 bits (189), Expect = 2e-14
Identities = 57/234 (24%), Positives = 115/234 (49%), Gaps = 9/234 (3%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+D LV+ ++ +KL+DV+S L+ GH+ V F IIS S D++V +W
Sbjct: 93 SDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIW 152
Query: 154 DISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--NHGS 211
++ T + + + H+D + A S +I+SGSYD +++D S + + T+ +
Sbjct: 153 EVKTGKCLKTLSAHSDPVSA-VHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNP 211
Query: 212 PVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQH--HKTVTTLRLASNNSR-L 267
PV F P+G ++A +K+WD ++ G+ L + H K + + +
Sbjct: 212 PVSFVKFSPNGKYILTATLDNTLKLWD-YSRGRCLKTYTGHKNEKYCIFANFSVTGGKWI 270
Query: 268 MSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISIR 320
+S S D V I+++ T ++V + + ++S A ++++ ++ +I+
Sbjct: 271 VSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIK 324
Score = 49.2 bits (112), Expect = 4e-05
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGP---VHRTFFTKDQLKIISYSDDK 148
F +G+ ++ + +KL+D L+ +TGH + F I+S S+D
Sbjct: 218 FSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDN 277
Query: 149 SVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSY--DHTVKLY 196
V +W++ T+E + HTD + + A P + ++I S + D T+KL+
Sbjct: 278 LVYIWNLQTKEIVQKLQGHTDVVISAACHP-TENLIASAALENDKTIKLW 326
Score = 44.4 bits (100), Expect = 0.001
Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
V H V S F P+G S+ I +W ++G K + H+ ++ + +S++S
Sbjct: 38 VGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDG-KYEKTLYGHNLEISDVAWSSDSS 96
Query: 266 RLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
RL+SAS D+ +K++DV + K + + N + + +++ G D + I
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKI 151
>AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ11287 fis, clone PLACE1009596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 330
Score = 91.9 bits (218), Expect = 5e-18
Identities = 48/200 (24%), Positives = 105/200 (52%), Gaps = 3/200 (1%)
Query: 85 EAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISY 144
EA F +G L + + + ++ + GH + ++ D +++S
Sbjct: 42 EAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSA 101
Query: 145 SDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI 204
SDDK++ LWD+ + + + H++Y+ +P S ++I+SGS+D TVK+++ ++ + +
Sbjct: 102 SDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPS-NLIISGSFDETVKIWEVKTGKCL 160
Query: 205 MTVN-HGSPVESTLFLPSGGIFISAGGTEI-KVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
T++ H PV + F SG + +S + ++WD +G L + + + V+ ++ +
Sbjct: 161 KTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSP 220
Query: 263 NNSRLMSASLDRHVKIYDVS 282
N +++A+LD +K++D S
Sbjct: 221 NGKYILTATLDNTLKLWDYS 240
Score = 79.8 bits (188), Expect = 2e-14
Identities = 56/233 (24%), Positives = 112/233 (48%), Gaps = 7/233 (3%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+D LV+ ++ +KL+DV+S L+ GH+ V F IIS S D++V +W
Sbjct: 93 SDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIW 152
Query: 154 DISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--NHGS 211
++ T + + + H+D + A S +I+SGSYD +++D S + + T+ +
Sbjct: 153 EVKTGKCLKTLSAHSDPVSA-VHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNP 211
Query: 212 PVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLR--LASNNSRLM 268
PV F P+G ++A +K+WD G L + Q ++ + ++
Sbjct: 212 PVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVTGGKWIV 271
Query: 269 SASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISIR 320
S S D V I+++ T ++V + + ++S A ++++ ++ +I+
Sbjct: 272 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIK 324
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/110 (25%), Positives = 53/110 (48%), Gaps = 6/110 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGP---VHRTFFTKDQLKIISYSDDK 148
F +G+ ++ + +KL+D L+ +TG + F I+S S+D
Sbjct: 218 FSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVTGGKWIVSGSEDN 277
Query: 149 SVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSY--DHTVKLY 196
V +W++ T+E + HTD + + A P + ++I S + D T+KL+
Sbjct: 278 LVYIWNLQTKEIVQKLQGHTDVVISAACHP-TENLIASAALENDKTIKLW 326
Score = 44.4 bits (100), Expect = 0.001
Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
V H V S F P+G S+ I +W ++G K + H+ ++ + +S++S
Sbjct: 38 VGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDG-KYEKTLYGHNLEISDVAWSSDSS 96
Query: 266 RLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
RL+SAS D+ +K++DV + K + + N + + +++ G D + I
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKI 151
>AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit
protein.
Length = 655
Score = 88.2 bits (209), Expect = 6e-17
Identities = 60/227 (26%), Positives = 96/227 (42%), Gaps = 5/227 (2%)
Query: 93 RADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
+A GRLL G ++ V L+ + N + TGHT PV + I++ S S+ +
Sbjct: 30 KASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRV 89
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGS 211
WD+ + + I + P + + SGS D +KL+D R + H
Sbjct: 90 WDLEAAKILRTLMGLKANICSLDFHPYG-EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQ 148
Query: 212 PVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
V F P G SA +K+WD+ GK++S H V + N L S
Sbjct: 149 AVRCLRFSPDGKWLASAADDHTVKLWDL-TAGKMMSEFPGHTGPVNVVEFHPNEYLLASG 207
Query: 271 SLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGI 316
S D ++ +D+ F+VV I+ P + S+ + L G D +
Sbjct: 208 SSDGTIRFWDLEKFQVVSRIEGEPGPVRSVLFNPDGCCLYSGCQDSL 254
Score = 53.2 bits (122), Expect = 2e-06
Identities = 30/131 (22%), Positives = 60/131 (45%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
LDF P + + + ++++D K +A F DG+ L + ++
Sbjct: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
VKL+D+ + ++ F GHTGPV+ F ++ + S S D ++ WD+ + ++
Sbjct: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDGTIRFWDLEKFQVVSRIEGE 230
Query: 168 TDYIRAGAASP 178
+R+ +P
Sbjct: 231 PGPVRSVLFNP 241
>EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein.
Length = 478
Score = 87.4 bits (207), Expect = 1e-16
Identities = 56/226 (24%), Positives = 107/226 (47%), Gaps = 5/226 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G LL + + V+L+ + F HT PV F+ D + + S+DKS+
Sbjct: 68 FSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIK 127
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGS 211
+W + + + + HT ++R SP +I+S S D T+K++D + + + +
Sbjct: 128 VWSMYRQRFLYSLYRHTHWVRCAKFSP-DGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSV 186
Query: 212 PVESTL-FLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + F PSG SAG + +KVWD+ KLL + H V + + + L++
Sbjct: 187 GFANFVDFNPSGTCIASAGSDQTVKVWDV-RVNKLLQHYQVHSGGVNCISFHPSGNYLIT 245
Query: 270 ASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMD 314
AS D +KI D+ ++++ + + +++ S+ ++ G D
Sbjct: 246 ASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGAD 291
Score = 80.2 bits (189), Expect = 2e-14
Identities = 51/190 (26%), Positives = 89/190 (46%), Gaps = 4/190 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F ADG+ L E+ ++K++ + + L HT V F+ D I+S S+DK++
Sbjct: 110 FSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIK 169
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HG 210
+WD + ++ + NF++ + +P I +GS D TVK++D R N+ + H
Sbjct: 170 IWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGS-DQTVKVWDVRVNKLLQHYQVHS 228
Query: 211 SPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V F PSG I+A +K+ D+ G+L+ + H V T+ + S
Sbjct: 229 GGVNCISFHPSGNYLITASSDGTLKILDLLE-GRLIYTLQGHTGPVFTVSFSKGGELFAS 287
Query: 270 ASLDRHVKIY 279
D V ++
Sbjct: 288 GGADTQVLLW 297
Score = 56.8 bits (131), Expect = 2e-07
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R F GH + + + ++ + S D + LW+ R + H D + + SP
Sbjct: 12 RYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSP- 70
Query: 180 SPDIILSGSYDHTVKLY--DCRSNETIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVW 236
+++ S S D TV+L+ D R + H +PV S F G +A IKVW
Sbjct: 71 HGNLLASASRDRTVRLWIPDKRGKFSEFKA-HTAPVRSVDFSADGQFLATASEDKSIKVW 129
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHN 289
++ + L ++ +H V + + + ++S S D+ +KI+D + + V+N
Sbjct: 130 SMYR-QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNN 181
Score = 50.8 bits (116), Expect = 1e-05
Identities = 44/201 (21%), Positives = 83/201 (41%), Gaps = 5/201 (2%)
Query: 122 FTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISP 181
+ GH V F+ + S S D++V LW + + F HT +R+ S
Sbjct: 56 YVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFS-ADG 114
Query: 182 DIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIF 239
+ + S D ++K++ + ++ H V F P G + +S + IK+WD
Sbjct: 115 QFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTT 174
Query: 240 NGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVV-HNIDFPNAILS 298
N + ++N S + + + + SA D+ VK++DV K++ H +
Sbjct: 175 N-KQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNC 233
Query: 299 MAISEHDDILTVGMMDGIISI 319
++ + L DG + I
Sbjct: 234 ISFHPSGNYLITASSDGTLKI 254
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/117 (23%), Positives = 47/117 (40%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G +++DF+P +A V+V+D + ++ F G L+
Sbjct: 187 GFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITA 246
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEE 159
+ +K+ D+ ++ GHTGPV F+K S D V LW + +E
Sbjct: 247 SSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDE 303
Score = 39.9 bits (89), Expect = 0.022
Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
FSP + + ++++D K N S V A F G + + + VK
Sbjct: 152 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 211
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
++DV+ +L+ + H+G V+ F +I+ S D ++ + D+ I HT
Sbjct: 212 VWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTG 271
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
+ + S ++ SG D V L+ +E
Sbjct: 272 PVFTVSFSK-GGELFASGGADTQVLLWRTNFDE 303
>BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B
protein.
Length = 478
Score = 87.4 bits (207), Expect = 1e-16
Identities = 56/226 (24%), Positives = 107/226 (47%), Gaps = 5/226 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G LL + + V+L+ + F HT PV F+ D + + S+DKS+
Sbjct: 68 FSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIK 127
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGS 211
+W + + + + HT ++R SP +I+S S D T+K++D + + + +
Sbjct: 128 VWSMYRQRFLYSLYRHTHWVRCAKFSP-DGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSV 186
Query: 212 PVESTL-FLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + F PSG SAG + +KVWD+ KLL + H V + + + L++
Sbjct: 187 GFANFVDFNPSGTCIASAGSDQTVKVWDV-RVNKLLQHYQVHSGGVNCISFHPSGNYLIT 245
Query: 270 ASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMD 314
AS D +KI D+ ++++ + + +++ S+ ++ G D
Sbjct: 246 ASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGAD 291
Score = 80.2 bits (189), Expect = 2e-14
Identities = 51/190 (26%), Positives = 89/190 (46%), Gaps = 4/190 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F ADG+ L E+ ++K++ + + L HT V F+ D I+S S+DK++
Sbjct: 110 FSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIK 169
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HG 210
+WD + ++ + NF++ + +P I +GS D TVK++D R N+ + H
Sbjct: 170 IWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGS-DQTVKVWDVRVNKLLQHYQVHS 228
Query: 211 SPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V F PSG I+A +K+ D+ G+L+ + H V T+ + S
Sbjct: 229 GGVNCISFHPSGNYLITASSDGTLKILDLLE-GRLIYTLQGHTGPVFTVSFSKGGELFAS 287
Query: 270 ASLDRHVKIY 279
D V ++
Sbjct: 288 GGADTQVLLW 297
Score = 56.8 bits (131), Expect = 2e-07
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R F GH + + + ++ + S D + LW+ R + H D + + SP
Sbjct: 12 RYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSP- 70
Query: 180 SPDIILSGSYDHTVKLY--DCRSNETIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVW 236
+++ S S D TV+L+ D R + H +PV S F G +A IKVW
Sbjct: 71 HGNLLASASRDRTVRLWIPDKRGKFSEFKA-HTAPVRSVDFSADGQFLATASEDKSIKVW 129
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHN 289
++ + L ++ +H V + + + ++S S D+ +KI+D + + V+N
Sbjct: 130 SMYR-QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNN 181
Score = 50.8 bits (116), Expect = 1e-05
Identities = 44/201 (21%), Positives = 83/201 (41%), Gaps = 5/201 (2%)
Query: 122 FTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISP 181
+ GH V F+ + S S D++V LW + + F HT +R+ S
Sbjct: 56 YVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFS-ADG 114
Query: 182 DIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIF 239
+ + S D ++K++ + ++ H V F P G + +S + IK+WD
Sbjct: 115 QFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTT 174
Query: 240 NGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVV-HNIDFPNAILS 298
N + ++N S + + + + SA D+ VK++DV K++ H +
Sbjct: 175 N-KQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNC 233
Query: 299 MAISEHDDILTVGMMDGIISI 319
++ + L DG + I
Sbjct: 234 ISFHPSGNYLITASSDGTLKI 254
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/117 (23%), Positives = 47/117 (40%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G +++DF+P +A V+V+D + ++ F G L+
Sbjct: 187 GFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITA 246
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEE 159
+ +K+ D+ ++ GHTGPV F+K S D V LW + +E
Sbjct: 247 SSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDE 303
Score = 39.9 bits (89), Expect = 0.022
Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
FSP + + ++++D K N S V A F G + + + VK
Sbjct: 152 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 211
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
++DV+ +L+ + H+G V+ F +I+ S D ++ + D+ I HT
Sbjct: 212 VWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTG 271
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
+ + S ++ SG D V L+ +E
Sbjct: 272 PVFTVSFSK-GGELFASGGADTQVLLWRTNFDE 303
>AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens
cDNA FLJ90291 fis, clone NT2RP1001031, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 478
Score = 87.4 bits (207), Expect = 1e-16
Identities = 56/226 (24%), Positives = 107/226 (47%), Gaps = 5/226 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G LL + + V+L+ + F HT PV F+ D + + S+DKS+
Sbjct: 68 FSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIK 127
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGS 211
+W + + + + HT ++R SP +I+S S D T+K++D + + + +
Sbjct: 128 VWSMYRQRFLYSLYRHTHWVRCAKFSP-DGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSV 186
Query: 212 PVESTL-FLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + F PSG SAG + +KVWD+ KLL + H V + + + L++
Sbjct: 187 GFANFVDFNPSGTCIASAGSDQTVKVWDV-RVNKLLQHYQVHSGGVNCISFHPSGNYLIT 245
Query: 270 ASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMD 314
AS D +KI D+ ++++ + + +++ S+ ++ G D
Sbjct: 246 ASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGAD 291
Score = 80.2 bits (189), Expect = 2e-14
Identities = 51/190 (26%), Positives = 89/190 (46%), Gaps = 4/190 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F ADG+ L E+ ++K++ + + L HT V F+ D I+S S+DK++
Sbjct: 110 FSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIK 169
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HG 210
+WD + ++ + NF++ + +P I +GS D TVK++D R N+ + H
Sbjct: 170 IWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGS-DQTVKVWDVRVNKLLQHYQVHS 228
Query: 211 SPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
V F PSG I+A +K+ D+ G+L+ + H V T+ + S
Sbjct: 229 GGVNCISFHPSGNYLITASSDGTLKILDLLE-GRLIYTLQGHTGPVFTVSFSKGGELFAS 287
Query: 270 ASLDRHVKIY 279
D V ++
Sbjct: 288 GGADTQVLLW 297
Score = 56.8 bits (131), Expect = 2e-07
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R F GH + + + ++ + S D + LW+ R + H D + + SP
Sbjct: 12 RYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSP- 70
Query: 180 SPDIILSGSYDHTVKLY--DCRSNETIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVW 236
+++ S S D TV+L+ D R + H +PV S F G +A IKVW
Sbjct: 71 HGNLLASASRDRTVRLWIPDKRGKFSEFKA-HTAPVRSVDFSADGQFLATASEDKSIKVW 129
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHN 289
++ + L ++ +H V + + + ++S S D+ +KI+D + + V+N
Sbjct: 130 SMYR-QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNN 181
Score = 50.8 bits (116), Expect = 1e-05
Identities = 44/201 (21%), Positives = 83/201 (41%), Gaps = 5/201 (2%)
Query: 122 FTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISP 181
+ GH V F+ + S S D++V LW + + F HT +R+ S
Sbjct: 56 YVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFS-ADG 114
Query: 182 DIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIF 239
+ + S D ++K++ + ++ H V F P G + +S + IK+WD
Sbjct: 115 QFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTT 174
Query: 240 NGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVV-HNIDFPNAILS 298
N + ++N S + + + + SA D+ VK++DV K++ H +
Sbjct: 175 N-KQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNC 233
Query: 299 MAISEHDDILTVGMMDGIISI 319
++ + L DG + I
Sbjct: 234 ISFHPSGNYLITASSDGTLKI 254
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/117 (23%), Positives = 47/117 (40%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G +++DF+P +A V+V+D + ++ F G L+
Sbjct: 187 GFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITA 246
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEE 159
+ +K+ D+ ++ GHTGPV F+K S D V LW + +E
Sbjct: 247 SSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDE 303
Score = 39.9 bits (89), Expect = 0.022
Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
FSP + + ++++D K N S V A F G + + + VK
Sbjct: 152 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 211
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
++DV+ +L+ + H+G V+ F +I+ S D ++ + D+ I HT
Sbjct: 212 VWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTG 271
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
+ + S ++ SG D V L+ +E
Sbjct: 272 PVFTVSFSK-GGELFASGGADTQVLLWRTNFDE 303
>BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 85.0 bits (201), Expect = 6e-16
Identities = 65/284 (22%), Positives = 131/284 (46%), Gaps = 9/284 (3%)
Query: 44 AIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGI 103
A+ + FSP + +++ ++++ K IS + +D LLV+
Sbjct: 47 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 106
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ +K++DV S L+ GH+ V F I+S S D+SV +WD+ T + +
Sbjct: 107 DDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKT 166
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--NHGSPVESTLFLPS 221
H+D + A + +I+S SYD +++D S + + T+ + PV F P+
Sbjct: 167 LPAHSDPVSAVHFNR-DGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
Query: 222 GGIFISAG-GTEIKVWDIFNGGKLLSNISQH--HKTVTTLRLASNNSR-LMSASLDRHVK 277
G ++A +K+WD ++ GK L + H K + + ++S S D V
Sbjct: 226 GKYILAATLDNTLKLWD-YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVY 284
Query: 278 IYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISIR 320
I+++ T ++V + + ++S A ++I+ ++ +I+
Sbjct: 285 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIK 328
Score = 57.6 bits (133), Expect = 1e-07
Identities = 42/162 (25%), Positives = 77/162 (47%), Gaps = 4/162 (2%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GHT V F+ + + S S DK + +W + + H I A S S ++
Sbjct: 43 GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS-NL 101
Query: 184 ILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNG 241
++S S D T+K++D S + + T+ H + V F P + +S E +++WD+
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV-KT 160
Query: 242 GKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
GK L + H V+ + + S ++S+S D +I+D ++
Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTAS 202
>BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 85.0 bits (201), Expect = 6e-16
Identities = 65/284 (22%), Positives = 131/284 (46%), Gaps = 9/284 (3%)
Query: 44 AIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGI 103
A+ + FSP + +++ ++++ K IS + +D LLV+
Sbjct: 47 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 106
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ +K++DV S L+ GH+ V F I+S S D+SV +WD+ T + +
Sbjct: 107 DDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKT 166
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--NHGSPVESTLFLPS 221
H+D + A + +I+S SYD +++D S + + T+ + PV F P+
Sbjct: 167 LPAHSDPVSAVHFNR-DGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
Query: 222 GGIFISAG-GTEIKVWDIFNGGKLLSNISQH--HKTVTTLRLASNNSR-LMSASLDRHVK 277
G ++A +K+WD ++ GK L + H K + + ++S S D V
Sbjct: 226 GKYILAATLDNTLKLWD-YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVY 284
Query: 278 IYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISIR 320
I+++ T ++V + + ++S A ++I+ ++ +I+
Sbjct: 285 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIK 328
Score = 57.6 bits (133), Expect = 1e-07
Identities = 42/162 (25%), Positives = 77/162 (47%), Gaps = 4/162 (2%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GHT V F+ + + S S DK + +W + + H I A S S ++
Sbjct: 43 GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS-NL 101
Query: 184 ILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNG 241
++S S D T+K++D S + + T+ H + V F P + +S E +++WD+
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV-KT 160
Query: 242 GKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
GK L + H V+ + + S ++S+S D +I+D ++
Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTAS 202
>AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens
cDNA FLJ20545 fis, clone KAT11476. ).
Length = 334
Score = 85.0 bits (201), Expect = 6e-16
Identities = 65/284 (22%), Positives = 131/284 (46%), Gaps = 9/284 (3%)
Query: 44 AIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGI 103
A+ + FSP + +++ ++++ K IS + +D LLV+
Sbjct: 47 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 106
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ +K++DV S L+ GH+ V F I+S S D+SV +WD+ T + +
Sbjct: 107 DDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKT 166
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--NHGSPVESTLFLPS 221
H+D + A + +I+S SYD +++D S + + T+ + PV F P+
Sbjct: 167 LPAHSDPVSAVHFNR-DGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
Query: 222 GGIFISAG-GTEIKVWDIFNGGKLLSNISQH--HKTVTTLRLASNNSR-LMSASLDRHVK 277
G ++A +K+WD ++ GK L + H K + + ++S S D V
Sbjct: 226 GKYILAATLDNTLKLWD-YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVY 284
Query: 278 IYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISIR 320
I+++ T ++V + + ++S A ++I+ ++ +I+
Sbjct: 285 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIK 328
Score = 57.6 bits (133), Expect = 1e-07
Identities = 42/162 (25%), Positives = 77/162 (47%), Gaps = 4/162 (2%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GHT V F+ + + S S DK + +W + + H I A S S ++
Sbjct: 43 GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS-NL 101
Query: 184 ILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNG 241
++S S D T+K++D S + + T+ H + V F P + +S E +++WD+
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV-KT 160
Query: 242 GKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
GK L + H V+ + + S ++S+S D +I+D ++
Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTAS 202
>AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein
protein.
Length = 362
Score = 85.0 bits (201), Expect = 6e-16
Identities = 65/284 (22%), Positives = 131/284 (46%), Gaps = 9/284 (3%)
Query: 44 AIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGI 103
A+ + FSP + +++ ++++ K IS + +D LLV+
Sbjct: 75 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 134
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ +K++DV S L+ GH+ V F I+S S D+SV +WD+ T + +
Sbjct: 135 DDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKT 194
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--NHGSPVESTLFLPS 221
H+D + A + +I+S SYD +++D S + + T+ + PV F P+
Sbjct: 195 LPAHSDPVSAVHFNR-DGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 253
Query: 222 GGIFISAG-GTEIKVWDIFNGGKLLSNISQH--HKTVTTLRLASNNSR-LMSASLDRHVK 277
G ++A +K+WD ++ GK L + H K + + ++S S D V
Sbjct: 254 GKYILAATLDNTLKLWD-YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVY 312
Query: 278 IYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISIR 320
I+++ T ++V + + ++S A ++I+ ++ +I+
Sbjct: 313 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIK 356
Score = 57.6 bits (133), Expect = 1e-07
Identities = 42/162 (25%), Positives = 77/162 (47%), Gaps = 4/162 (2%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GHT V F+ + + S S DK + +W + + H I A S S ++
Sbjct: 71 GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS-NL 129
Query: 184 ILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNG 241
++S S D T+K++D S + + T+ H + V F P + +S E +++WD+
Sbjct: 130 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV-KT 188
Query: 242 GKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
GK L + H V+ + + S ++S+S D +I+D ++
Sbjct: 189 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTAS 230
>BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1
(PRL1 homolog, Arabidopsis) protein.
Length = 514
Score = 84.2 bits (199), Expect = 1e-15
Identities = 63/298 (21%), Positives = 132/298 (44%), Gaps = 13/298 (4%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
V+ G + + P ++ + ++++D + + +++ + G
Sbjct: 199 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 258
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIS 156
L + E+ VK +D++ V+R + GH V+ +++ S D + +WD+
Sbjct: 259 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 318
Query: 157 TEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVES 215
T+ + + HT+ + P II +GS+D T++L+D + +T +T+ NH V +
Sbjct: 319 TKASVHTLSGHTNAVATVRCQAAEPQII-TGSHDTTIRLWDLVAGKTRVTLTNHKKSVRA 377
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
+ P F S IK W F G + N+S H+ + TL + S+ L+S + +
Sbjct: 378 VVLHPRHYTFASGSPDNIKQWK-FPDGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGT 435
Query: 276 VKIYDVST---FKVVH------NIDFPNAILSMAISEHDDILTVGMMDGIISIRKREE 324
+ ++D T F+ VH ++D + I + A + + L D I + + ++
Sbjct: 436 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYREDD 493
Score = 52.4 bits (120), Expect = 4e-06
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
RV +GH G V ++ S D+++ +WD+++ + + H +R S
Sbjct: 198 RVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 257
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAG-GTEIKVWD 237
SP + G D VK +D N+ I + H S V P+ + ++ + ++WD
Sbjct: 258 SPYLFSCGE-DKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWD 316
Query: 238 IFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+ + +S H V T+R + ++++ S D ++++D+
Sbjct: 317 VRTKAS-VHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 359
>BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein.
Length = 505
Score = 84.2 bits (199), Expect = 1e-15
Identities = 63/298 (21%), Positives = 132/298 (44%), Gaps = 13/298 (4%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
V+ G + + P ++ + ++++D + + +++ + G
Sbjct: 190 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 249
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIS 156
L + E+ VK +D++ V+R + GH V+ +++ S D + +WD+
Sbjct: 250 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 309
Query: 157 TEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVES 215
T+ + + HT+ + P II +GS+D T++L+D + +T +T+ NH V +
Sbjct: 310 TKASVHTLSGHTNAVATVRCQAAEPQII-TGSHDTTIRLWDLVAGKTRVTLTNHKKSVRA 368
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
+ P F S IK W F G + N+S H+ + TL + S+ L+S + +
Sbjct: 369 VVLHPRHYTFASGSPDNIKQWK-FPDGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGT 426
Query: 276 VKIYDVST---FKVVH------NIDFPNAILSMAISEHDDILTVGMMDGIISIRKREE 324
+ ++D T F+ VH ++D + I + A + + L D I + + ++
Sbjct: 427 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYREDD 484
Score = 52.4 bits (120), Expect = 4e-06
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
RV +GH G V ++ S D+++ +WD+++ + + H +R S
Sbjct: 189 RVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 248
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAG-GTEIKVWD 237
SP + G D VK +D N+ I + H S V P+ + ++ + ++WD
Sbjct: 249 SPYLFSCGE-DKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWD 307
Query: 238 IFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+ + +S H V T+R + ++++ S D ++++D+
Sbjct: 308 VRTKAS-VHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 350
>AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1
protein.
Length = 514
Score = 84.2 bits (199), Expect = 1e-15
Identities = 63/298 (21%), Positives = 132/298 (44%), Gaps = 13/298 (4%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
V+ G + + P ++ + ++++D + + +++ + G
Sbjct: 199 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 258
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIS 156
L + E+ VK +D++ V+R + GH V+ +++ S D + +WD+
Sbjct: 259 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 318
Query: 157 TEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVES 215
T+ + + HT+ + P II +GS+D T++L+D + +T +T+ NH V +
Sbjct: 319 TKASVHTLSGHTNAVATVRCQAAEPQII-TGSHDTTIRLWDLVAGKTRVTLTNHKKSVRA 377
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
+ P F S IK W F G + N+S H+ + TL + S+ L+S + +
Sbjct: 378 VVLHPRHYTFASGSPDNIKQWK-FPDGSFIQNLSGHNAIINTLTVNSDGV-LVSGADNGT 435
Query: 276 VKIYDVST---FKVVH------NIDFPNAILSMAISEHDDILTVGMMDGIISIRKREE 324
+ ++D T F+ VH ++D + I + A + + L D I + + ++
Sbjct: 436 MHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYREDD 493
Score = 52.4 bits (120), Expect = 4e-06
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
RV +GH G V ++ S D+++ +WD+++ + + H +R S
Sbjct: 198 RVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTR 257
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAG-GTEIKVWD 237
SP + G D VK +D N+ I + H S V P+ + ++ + ++WD
Sbjct: 258 SPYLFSCGE-DKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWD 316
Query: 238 IFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+ + +S H V T+R + ++++ S D ++++D+
Sbjct: 317 VRTKAS-VHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 359
>AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymerase
II, p300/CBP-associated factor (PCAF)-associated facto
protein.
Length = 589
Score = 78.6 bits (185), Expect = 5e-14
Identities = 51/196 (26%), Positives = 94/196 (47%), Gaps = 4/196 (2%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F AD L++ E+ +++ +D+ S ++ GH PV + L S S D
Sbjct: 346 YSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHD 405
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MT 206
++ LW + + H + P S + + +GS D TV+L+ + ++ +
Sbjct: 406 RTARLWSFDRTYPLRIYAGHLADVDCVKFHPNS-NYLATGSTDKTVRLWSAQQGNSVRLF 464
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H PV S F P+G SAG + +K+WD+ + G L + H +T+L + ++
Sbjct: 465 TGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLAS-GTLYKELRGHTDNITSLTFSPDSG 523
Query: 266 RLMSASLDRHVKIYDV 281
+ SAS+D V+++D+
Sbjct: 524 LIASASMDNSVRVWDI 539
Score = 70.1 bits (164), Expect = 2e-11
Identities = 48/205 (23%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
+++ GH GPV+ T F D ++S S+D S+ WD+ + + H + SP
Sbjct: 335 MKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISP 394
Query: 179 ISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE--IKV 235
S SGS+D T +L+ R+ + H + V+ F P+ +++ G T+ +++
Sbjct: 395 YSL-YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSN-YLATGSTDKTVRL 452
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPN 294
W G + + H V +L + N L SA D+ +K++D+++ + + +
Sbjct: 453 WSAQQGNS-VRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTD 511
Query: 295 AILSMAISEHDDILTVGMMDGIISI 319
I S+ S ++ MD + +
Sbjct: 512 NITSLTFSPDSGLIASASMDNSVRV 536
Score = 66.1 bits (154), Expect = 3e-10
Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + L G + V+L+ Q N +R+FTGH GPV F+ + + S +D+ +
Sbjct: 434 FHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLK 493
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRS 200
LWD+++ HTD I + SP S +I S S D++V+++D R+
Sbjct: 494 LWDLASGTLYKELRGHTDNITSLTFSPDS-GLIASASMDNSVRVWDIRN 541
Score = 54.8 bits (126), Expect = 7e-07
Identities = 37/142 (26%), Positives = 59/142 (41%), Gaps = 3/142 (2%)
Query: 101 AGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEER 160
+G + +L+ LR++ GH V F + + + S DK+V LW
Sbjct: 401 SGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNS 460
Query: 161 IANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFL 219
+ F H + + A SP + + S D +KL+D S + H + S F
Sbjct: 461 VRLFTGHRGPVLSLAFSP-NGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFS 519
Query: 220 PSGGIFISAG-GTEIKVWDIFN 240
P G+ SA ++VWDI N
Sbjct: 520 PDSGLIASASMDNSVRVWDIRN 541
>AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription
factor protein.
Length = 260
Score = 78.6 bits (185), Expect = 5e-14
Identities = 51/196 (26%), Positives = 94/196 (47%), Gaps = 4/196 (2%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F AD L++ E+ +++ +D+ S ++ GH PV + L S S D
Sbjct: 17 YSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHD 76
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MT 206
++ LW + + H + P S + + +GS D TV+L+ + ++ +
Sbjct: 77 RTARLWSFDRTYPLRIYAGHLADVDCVKFHPNS-NYLATGSTDKTVRLWSAQQGNSVRLF 135
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H PV S F P+G SAG + +K+WD+ + G L + H +T+L + ++
Sbjct: 136 TGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLAS-GTLYKELRGHTDNITSLTFSPDSG 194
Query: 266 RLMSASLDRHVKIYDV 281
+ SAS+D V+++D+
Sbjct: 195 LIASASMDNSVRVWDI 210
Score = 70.1 bits (164), Expect = 2e-11
Identities = 48/205 (23%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
+++ GH GPV+ T F D ++S S+D S+ WD+ + + H + SP
Sbjct: 6 MKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISP 65
Query: 179 ISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE--IKV 235
S SGS+D T +L+ R+ + H + V+ F P+ +++ G T+ +++
Sbjct: 66 YSL-YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSN-YLATGSTDKTVRL 123
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPN 294
W G + + H V +L + N L SA D+ +K++D+++ + + +
Sbjct: 124 WSAQQGNS-VRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTD 182
Query: 295 AILSMAISEHDDILTVGMMDGIISI 319
I S+ S ++ MD + +
Sbjct: 183 NITSLTFSPDSGLIASASMDNSVRV 207
Score = 66.1 bits (154), Expect = 3e-10
Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + L G + V+L+ Q N +R+FTGH GPV F+ + + S +D+ +
Sbjct: 105 FHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLK 164
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRS 200
LWD+++ HTD I + SP S +I S S D++V+++D R+
Sbjct: 165 LWDLASGTLYKELRGHTDNITSLTFSPDS-GLIASASMDNSVRVWDIRN 212
Score = 54.8 bits (126), Expect = 7e-07
Identities = 37/142 (26%), Positives = 59/142 (41%), Gaps = 3/142 (2%)
Query: 101 AGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEER 160
+G + +L+ LR++ GH V F + + + S DK+V LW
Sbjct: 72 SGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNS 131
Query: 161 IANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFL 219
+ F H + + A SP + + S D +KL+D S + H + S F
Sbjct: 132 VRLFTGHRGPVLSLAFSP-NGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFS 190
Query: 220 PSGGIFISAG-GTEIKVWDIFN 240
P G+ SA ++VWDI N
Sbjct: 191 PDSGLIASASMDNSVRVWDIRN 212
>AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor 65
beta protein.
Length = 589
Score = 78.6 bits (185), Expect = 5e-14
Identities = 51/196 (26%), Positives = 94/196 (47%), Gaps = 4/196 (2%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F AD L++ E+ +++ +D+ S ++ GH PV + L S S D
Sbjct: 346 YSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHD 405
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MT 206
++ LW + + H + P S + + +GS D TV+L+ + ++ +
Sbjct: 406 RTARLWSFDRTYPLRIYAGHLADVDCVKFHPNS-NYLATGSTDKTVRLWSAQQGNSVRLF 464
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H PV S F P+G SAG + +K+WD+ + G L + H +T+L + ++
Sbjct: 465 TGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLAS-GTLYKELRGHTDNITSLTFSPDSG 523
Query: 266 RLMSASLDRHVKIYDV 281
+ SAS+D V+++D+
Sbjct: 524 LIASASMDNSVRVWDI 539
Score = 70.1 bits (164), Expect = 2e-11
Identities = 48/205 (23%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
+++ GH GPV+ T F D ++S S+D S+ WD+ + + H + SP
Sbjct: 335 MKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISP 394
Query: 179 ISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE--IKV 235
S SGS+D T +L+ R+ + H + V+ F P+ +++ G T+ +++
Sbjct: 395 YSL-YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSN-YLATGSTDKTVRL 452
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPN 294
W G + + H V +L + N L SA D+ +K++D+++ + + +
Sbjct: 453 WSAQQGNS-VRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTD 511
Query: 295 AILSMAISEHDDILTVGMMDGIISI 319
I S+ S ++ MD + +
Sbjct: 512 NITSLTFSPDSGLIASASMDNSVRV 536
Score = 66.1 bits (154), Expect = 3e-10
Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + L G + V+L+ Q N +R+FTGH GPV F+ + + S +D+ +
Sbjct: 434 FHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLK 493
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRS 200
LWD+++ HTD I + SP S +I S S D++V+++D R+
Sbjct: 494 LWDLASGTLYKELRGHTDNITSLTFSPDS-GLIASASMDNSVRVWDIRN 541
Score = 54.8 bits (126), Expect = 7e-07
Identities = 37/142 (26%), Positives = 59/142 (41%), Gaps = 3/142 (2%)
Query: 101 AGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEER 160
+G + +L+ LR++ GH V F + + + S DK+V LW
Sbjct: 401 SGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNS 460
Query: 161 IANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFL 219
+ F H + + A SP + + S D +KL+D S + H + S F
Sbjct: 461 VRLFTGHRGPVLSLAFSP-NGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFS 519
Query: 220 PSGGIFISAG-GTEIKVWDIFN 240
P G+ SA ++VWDI N
Sbjct: 520 PDSGLIASASMDNSVRVWDIRN 541
>BC127949-1|AAI27950.1| 314|Homo sapiens similar to hypothetical
protein FLJ25955 protein.
Length = 314
Score = 77.8 bits (183), Expect = 9e-14
Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 6/203 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F DG L + + V+L+DV LRV GH V F+ D ++ S DK V
Sbjct: 71 FSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVM 130
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT----V 207
LWD+ + + + H D I++ SP + + + +GS+D TV+++D R ++
Sbjct: 131 LWDVQSGQMLRLLVGHRDSIQSSDFSP-TVNCLATGSWDSTVRIWDLRMVTPAVSHQALE 189
Query: 208 NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H + + SG + + I +W LL + H V ++ + + L
Sbjct: 190 GHSGNISCLCYSASGLLASGSWDKTIHIWKP-TTSSLLIQLKGHVTWVKSIAFSPDELWL 248
Query: 268 MSASLDRHVKIYDVSTFKVVHNI 290
SA R VK++D +T K + +
Sbjct: 249 ASAGYSRMVKVWDCNTGKCLETL 271
Score = 71.7 bits (168), Expect = 6e-12
Identities = 52/196 (26%), Positives = 95/196 (48%), Gaps = 6/196 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F DG++L+ G E+ V ++ +S +L GHTGPV F+ D S S D +V
Sbjct: 29 FSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTVR 88
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHG 210
LWD++ + + H + + SP S + SG +D V L+D +S + + + V H
Sbjct: 89 LWDVARAKCLRVLKGHQRSVETVSFSPDSRQ-LASGGWDKRVMLWDVQSGQMLRLLVGHR 147
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSN--ISQHHKTVTTLRLASNNSRL 267
++S+ F P+ + + +++WD+ +S+ + H ++ L S + L
Sbjct: 148 DSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNISCL-CYSASGLL 206
Query: 268 MSASLDRHVKIYDVST 283
S S D+ + I+ +T
Sbjct: 207 ASGSWDKTIHIWKPTT 222
Score = 68.5 bits (160), Expect = 5e-11
Identities = 59/237 (24%), Positives = 102/237 (43%), Gaps = 8/237 (3%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + + FSP + +A+C V+++D + + + F D R L +G
Sbjct: 64 GPVKFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASG 123
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIA 162
+ V L+DVQS +LR+ GH + + F+ + + S D +V +WD+
Sbjct: 124 GWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAV 183
Query: 163 N---FNEHTDYIRAGAASPISPDIILSGSYDHTVKLY-DCRSNETIMTVNHGSPVESTLF 218
+ H+ I S + ++ SGS+D T+ ++ S+ I H + V+S F
Sbjct: 184 SHQALEGHSGNISCLCYS--ASGLLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAF 241
Query: 219 LPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDR 274
P SAG + +KVWD N GK L + T + L+S + D+
Sbjct: 242 SPDELWLASAGYSRMVKVWDC-NTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQ 297
Score = 54.4 bits (125), Expect = 9e-07
Identities = 39/165 (23%), Positives = 76/165 (46%), Gaps = 4/165 (2%)
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
++ F H G V+ + F+ D +++ S+D V W+ + + + HT ++ SP
Sbjct: 14 VKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSP 73
Query: 179 ISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAG-GTEIKVW 236
+ S S D TV+L+D + + + H VE+ F P S G + +W
Sbjct: 74 -DGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLW 132
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
D+ G++L + H ++ + + + L + S D V+I+D+
Sbjct: 133 DV-QSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDL 176
Score = 42.7 bits (96), Expect = 0.003
Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 9/163 (5%)
Query: 35 LPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGG---- 90
L +LV +I DFSP + V+++D ++V +S + G
Sbjct: 140 LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWD--LRMVTPAVSHQALEGHSGNISC 197
Query: 91 -CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKS 149
C+ A G LL +G + + ++ + ++L GH V F+ D+L + S +
Sbjct: 198 LCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRM 256
Query: 150 VGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHT 192
V +WD +T + + D A +P I++SG+ D T
Sbjct: 257 VKVWDCNTGKCLETLKGVLDVAHTCAFTP-DGKILVSGAADQT 298
Score = 34.3 bits (75), Expect = 1.1
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
HG V S+ F P G + ++ + W+ G+LL + H V R + +
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWET-RSGQLLWRLGGHTGPVKFCRFSPDGHLF 78
Query: 268 MSASLDRHVKIYDVSTFK 285
SAS D V+++DV+ K
Sbjct: 79 ASASCDCTVRLWDVARAK 96
Score = 33.1 bits (72), Expect = 2.5
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 30 WKKLGLPVLVKEFGAIDYLD---FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEA 86
WK +L++ G + ++ FSP E + +A S V+V+D T + + ++
Sbjct: 218 WKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDV 277
Query: 87 AYGGCFRADGRLLVAGIEEAAVKLFDVQSKN 117
A+ F DG++LV+G + + SK+
Sbjct: 278 AHTCAFTPDGKILVSGAADQTRRQISRTSKS 308
>AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38
protein.
Length = 314
Score = 77.0 bits (181), Expect = 2e-13
Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 6/203 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F DG L + + V+L+DV LRV GH V F+ D ++ S DK V
Sbjct: 71 FSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVM 130
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT----V 207
LWD+ + + + H D I++ SP + + + +GS+D TV ++D R ++
Sbjct: 131 LWDVQSGQMLRLLVGHRDSIQSSDFSP-TVNCLATGSWDSTVHIWDLRMVTPAVSHQALE 189
Query: 208 NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H + + + SG + + I +W LL + H V ++ + + L
Sbjct: 190 GHSANISCLCYSASGLLASGSWDKTIHIWKP-TTSSLLIQLKGHVTWVKSIAFSPDELWL 248
Query: 268 MSASLDRHVKIYDVSTFKVVHNI 290
SA R VK++D +T K + +
Sbjct: 249 ASAGYSRMVKVWDCNTGKCLETL 271
Score = 70.9 bits (166), Expect = 1e-11
Identities = 51/195 (26%), Positives = 93/195 (47%), Gaps = 4/195 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F DG++L+ G E+ V ++ +S +L GHTGPV F+ D S S D +V
Sbjct: 29 FSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTVR 88
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHG 210
LWD++ + + H + + SP S + SG +D V L+D +S + + + V H
Sbjct: 89 LWDVARAKCLRVLKGHQRSVETVSFSPDSRQ-LASGGWDKRVMLWDVQSGQMLRLLVGHR 147
Query: 211 SPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNIS-QHHKTVTTLRLASNNSRLM 268
++S+ F P+ + + + +WD+ +S+ + + H + S + L
Sbjct: 148 DSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASGLLA 207
Query: 269 SASLDRHVKIYDVST 283
S S D+ + I+ +T
Sbjct: 208 SGSWDKTIHIWKPTT 222
Score = 68.1 bits (159), Expect = 7e-11
Identities = 59/237 (24%), Positives = 102/237 (43%), Gaps = 8/237 (3%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + + FSP + +A+C V+++D + + + F D R L +G
Sbjct: 64 GPVKFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASG 123
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIA 162
+ V L+DVQS +LR+ GH + + F+ + + S D +V +WD+
Sbjct: 124 GWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAV 183
Query: 163 N---FNEHTDYIRAGAASPISPDIILSGSYDHTVKLY-DCRSNETIMTVNHGSPVESTLF 218
+ H+ I S + ++ SGS+D T+ ++ S+ I H + V+S F
Sbjct: 184 SHQALEGHSANISCLCYS--ASGLLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAF 241
Query: 219 LPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDR 274
P SAG + +KVWD N GK L + T + L+S + D+
Sbjct: 242 SPDELWLASAGYSRMVKVWDC-NTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQ 297
Score = 54.8 bits (126), Expect = 7e-07
Identities = 50/208 (24%), Positives = 91/208 (43%), Gaps = 7/208 (3%)
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
++ F H G V+ + F+ D +++ S+D V W+ + + + HT ++ SP
Sbjct: 14 VKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSP 73
Query: 179 ISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAG-GTEIKVW 236
+ S S D TV+L+D + + + H VE+ F P S G + +W
Sbjct: 74 -DGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLW 132
Query: 237 DIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVS--TFKVVHN-IDFP 293
D+ G++L + H ++ + + + L + S D V I+D+ T V H ++
Sbjct: 133 DV-QSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGH 191
Query: 294 NAILSMAISEHDDILTVGMMDGIISIRK 321
+A +S +L G D I I K
Sbjct: 192 SANISCLCYSASGLLASGSWDKTIHIWK 219
Score = 41.5 bits (93), Expect = 0.007
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 5/161 (3%)
Query: 35 LPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYD--PVTKVVAKNISKFVEAAYGG-C 91
L +LV +I DFSP + V ++D VT V+ + A C
Sbjct: 140 LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLC 199
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ A G LL +G + + ++ + ++L GH V F+ D+L + S + V
Sbjct: 200 YSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVK 258
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHT 192
+WD +T + + D A +P I++SG+ D T
Sbjct: 259 VWDCNTGKCLETLKGVLDVAHTCAFTP-DGKILVSGAADQT 298
Score = 33.1 bits (72), Expect = 2.5
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 30 WKKLGLPVLVKEFGAIDYLD---FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEA 86
WK +L++ G + ++ FSP E + +A S V+V+D T + + ++
Sbjct: 218 WKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDV 277
Query: 87 AYGGCFRADGRLLVAGIEEAAVKLFDVQSKN 117
A+ F DG++LV+G + + SK+
Sbjct: 278 AHTCAFTPDGKILVSGAADQTRRQISRTSKS 308
>X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein.
Length = 799
Score = 76.6 bits (180), Expect = 2e-13
Identities = 48/220 (21%), Positives = 104/220 (47%), Gaps = 7/220 (3%)
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ ++ D ++ + L++ GH+GPV+ F+ D+ ++S S+D +V LW + T +
Sbjct: 521 DDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVESTLFLPSG 222
+ H + SP +SG +D +L+ + + + H + V T F P+
Sbjct: 581 YKGHNYPVWDTQFSPYG-YYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNS 639
Query: 223 GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+++ G + +++WD+ N G + + H + +L + N L + + D V ++D
Sbjct: 640 N-YVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 281 VSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
+ +V + + + S+ S +IL G MD + +
Sbjct: 698 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRL 737
Score = 66.9 bits (156), Expect = 2e-10
Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + G + V+L+DV + N +R+FTGH GP+H F+ + + + + D V
Sbjct: 635 FHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVL 694
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD 197
LWDI + HTD + + S +I+ SGS D+TV+L+D
Sbjct: 695 LWDIGHGLMVGELKGHTDTVCSLRFSR-DGEILASGSMDNTVRLWD 739
Score = 51.2 bits (117), Expect = 9e-06
Identities = 47/205 (22%), Positives = 80/205 (39%), Gaps = 3/205 (1%)
Query: 35 LPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRA 94
L +L G + FSP Y +++ V+++ T + F
Sbjct: 536 LKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 595
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
G V+G + +L+ LR+F GH V+ T F + + + S D++V LWD
Sbjct: 596 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ + F H I + SP + + +G+ D V L+D + + H V
Sbjct: 656 VLNGNCVRIFTGHKGPIHSLTFSP-NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTV 714
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWD 237
S F G I S +++WD
Sbjct: 715 CSLRFSRDGEILASGSMDNTVRLWD 739
>U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100
protein.
Length = 800
Score = 76.6 bits (180), Expect = 2e-13
Identities = 48/220 (21%), Positives = 104/220 (47%), Gaps = 7/220 (3%)
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ ++ D ++ + L++ GH+GPV+ F+ D+ ++S S+D +V LW + T +
Sbjct: 521 DDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVESTLFLPSG 222
+ H + SP +SG +D +L+ + + + H + V T F P+
Sbjct: 581 YKGHNYPVWDTQFSPYG-YYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNS 639
Query: 223 GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+++ G + +++WD+ N G + + H + +L + N L + + D V ++D
Sbjct: 640 N-YVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 281 VSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
+ +V + + + S+ S +IL G MD + +
Sbjct: 698 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRL 737
Score = 66.9 bits (156), Expect = 2e-10
Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + G + V+L+DV + N +R+FTGH GP+H F+ + + + + D V
Sbjct: 635 FHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVL 694
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD 197
LWDI + HTD + + S +I+ SGS D+TV+L+D
Sbjct: 695 LWDIGHGLMVGELKGHTDTVCSLRFSR-DGEILASGSMDNTVRLWD 739
Score = 51.2 bits (117), Expect = 9e-06
Identities = 47/205 (22%), Positives = 80/205 (39%), Gaps = 3/205 (1%)
Query: 35 LPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRA 94
L +L G + FSP Y +++ V+++ T + F
Sbjct: 536 LKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 595
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
G V+G + +L+ LR+F GH V+ T F + + + S D++V LWD
Sbjct: 596 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ + F H I + SP + + +G+ D V L+D + + H V
Sbjct: 656 VLNGNCVRIFTGHKGPIHSLTFSP-NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTV 714
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWD 237
S F G I S +++WD
Sbjct: 715 CSLRFSRDGEILASGSMDNTVRLWD 739
>U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor
protein.
Length = 801
Score = 76.6 bits (180), Expect = 2e-13
Identities = 48/220 (21%), Positives = 104/220 (47%), Gaps = 7/220 (3%)
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ ++ D ++ + L++ GH+GPV+ F+ D+ ++S S+D +V LW + T +
Sbjct: 522 DDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 581
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVESTLFLPSG 222
+ H + SP +SG +D +L+ + + + H + V T F P+
Sbjct: 582 YKGHNYPVWDTQFSPYG-YYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNS 640
Query: 223 GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+++ G + +++WD+ N G + + H + +L + N L + + D V ++D
Sbjct: 641 N-YVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 698
Query: 281 VSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
+ +V + + + S+ S +IL G MD + +
Sbjct: 699 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRL 738
Score = 66.9 bits (156), Expect = 2e-10
Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + G + V+L+DV + N +R+FTGH GP+H F+ + + + + D V
Sbjct: 636 FHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVL 695
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD 197
LWDI + HTD + + S +I+ SGS D+TV+L+D
Sbjct: 696 LWDIGHGLMVGELKGHTDTVCSLRFSR-DGEILASGSMDNTVRLWD 740
Score = 51.2 bits (117), Expect = 9e-06
Identities = 47/205 (22%), Positives = 80/205 (39%), Gaps = 3/205 (1%)
Query: 35 LPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRA 94
L +L G + FSP Y +++ V+++ T + F
Sbjct: 537 LKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 596
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
G V+G + +L+ LR+F GH V+ T F + + + S D++V LWD
Sbjct: 597 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 656
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ + F H I + SP + + +G+ D V L+D + + H V
Sbjct: 657 VLNGNCVRIFTGHKGPIHSLTFSP-NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTV 715
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWD 237
S F G I S +++WD
Sbjct: 716 CSLRFSRDGEILASGSMDNTVRLWD 740
>BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 76.6 bits (180), Expect = 2e-13
Identities = 48/220 (21%), Positives = 104/220 (47%), Gaps = 7/220 (3%)
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ ++ D ++ + L++ GH+GPV+ F+ D+ ++S S+D +V LW + T +
Sbjct: 521 DDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVESTLFLPSG 222
+ H + SP +SG +D +L+ + + + H + V T F P+
Sbjct: 581 YKGHNYPVWDTQFSPYG-YYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNS 639
Query: 223 GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+++ G + +++WD+ N G + + H + +L + N L + + D V ++D
Sbjct: 640 N-YVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 281 VSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
+ +V + + + S+ S +IL G MD + +
Sbjct: 698 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRL 737
Score = 66.9 bits (156), Expect = 2e-10
Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + G + V+L+DV + N +R+FTGH GP+H F+ + + + + D V
Sbjct: 635 FHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVL 694
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD 197
LWDI + HTD + + S +I+ SGS D+TV+L+D
Sbjct: 695 LWDIGHGLMVGELKGHTDTVCSLRFSR-DGEILASGSMDNTVRLWD 739
Score = 51.2 bits (117), Expect = 9e-06
Identities = 47/205 (22%), Positives = 80/205 (39%), Gaps = 3/205 (1%)
Query: 35 LPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRA 94
L +L G + FSP Y +++ V+++ T + F
Sbjct: 536 LKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 595
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
G V+G + +L+ LR+F GH V+ T F + + + S D++V LWD
Sbjct: 596 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ + F H I + SP + + +G+ D V L+D + + H V
Sbjct: 656 VLNGNCVRIFTGHKGPIHSLTFSP-NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTV 714
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWD 237
S F G I S +++WD
Sbjct: 715 CSLRFSRDGEILASGSMDNTVRLWD 739
>AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 76.6 bits (180), Expect = 2e-13
Identities = 48/220 (21%), Positives = 104/220 (47%), Gaps = 7/220 (3%)
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ ++ D ++ + L++ GH+GPV+ F+ D+ ++S S+D +V LW + T +
Sbjct: 521 DDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVESTLFLPSG 222
+ H + SP +SG +D +L+ + + + H + V T F P+
Sbjct: 581 YKGHNYPVWDTQFSPYG-YYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNS 639
Query: 223 GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+++ G + +++WD+ N G + + H + +L + N L + + D V ++D
Sbjct: 640 N-YVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 281 VSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
+ +V + + + S+ S +IL G MD + +
Sbjct: 698 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRL 737
Score = 66.9 bits (156), Expect = 2e-10
Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + G + V+L+DV + N +R+FTGH GP+H F+ + + + + D V
Sbjct: 635 FHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVL 694
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD 197
LWDI + HTD + + S +I+ SGS D+TV+L+D
Sbjct: 695 LWDIGHGLMVGELKGHTDTVCSLRFSR-DGEILASGSMDNTVRLWD 739
Score = 51.2 bits (117), Expect = 9e-06
Identities = 47/205 (22%), Positives = 80/205 (39%), Gaps = 3/205 (1%)
Query: 35 LPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRA 94
L +L G + FSP Y +++ V+++ T + F
Sbjct: 536 LKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 595
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
G V+G + +L+ LR+F GH V+ T F + + + S D++V LWD
Sbjct: 596 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ + F H I + SP + + +G+ D V L+D + + H V
Sbjct: 656 VLNGNCVRIFTGHKGPIHSLTFSP-NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTV 714
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWD 237
S F G I S +++WD
Sbjct: 715 CSLRFSRDGEILASGSMDNTVRLWD 739
>AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiation
factor TFIID subunit 5 variant protein.
Length = 803
Score = 76.6 bits (180), Expect = 2e-13
Identities = 48/220 (21%), Positives = 104/220 (47%), Gaps = 7/220 (3%)
Query: 104 EEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN 163
++ ++ D ++ + L++ GH+GPV+ F+ D+ ++S S+D +V LW + T +
Sbjct: 524 DDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 583
Query: 164 FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVESTLFLPSG 222
+ H + SP +SG +D +L+ + + + H + V T F P+
Sbjct: 584 YKGHNYPVWDTQFSPYG-YYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNS 642
Query: 223 GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+++ G + +++WD+ N G + + H + +L + N L + + D V ++D
Sbjct: 643 N-YVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 700
Query: 281 VSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
+ +V + + + S+ S +IL G MD + +
Sbjct: 701 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRL 740
Score = 66.9 bits (156), Expect = 2e-10
Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F + + G + V+L+DV + N +R+FTGH GP+H F+ + + + + D V
Sbjct: 638 FHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVL 697
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD 197
LWDI + HTD + + S +I+ SGS D+TV+L+D
Sbjct: 698 LWDIGHGLMVGELKGHTDTVCSLRFSR-DGEILASGSMDNTVRLWD 742
Score = 51.2 bits (117), Expect = 9e-06
Identities = 47/205 (22%), Positives = 80/205 (39%), Gaps = 3/205 (1%)
Query: 35 LPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRA 94
L +L G + FSP Y +++ V+++ T + F
Sbjct: 539 LKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 598
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
G V+G + +L+ LR+F GH V+ T F + + + S D++V LWD
Sbjct: 599 YGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 658
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ + F H I + SP + + +G+ D V L+D + + H V
Sbjct: 659 VLNGNCVRIFTGHKGPIHSLTFSP-NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTV 717
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWD 237
S F G I S +++WD
Sbjct: 718 CSLRFSRDGEILASGSMDNTVRLWD 742
>BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein.
Length = 621
Score = 75.8 bits (178), Expect = 4e-13
Identities = 52/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C R DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 420 CVRYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 477
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 478 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 534
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 535 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 593
Query: 265 SRLMSA 270
++L+ A
Sbjct: 594 TKLVCA 599
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 300 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 357
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 358 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 414
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 415 VAAVRCVRY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 470
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 471 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 519
Score = 69.3 bits (162), Expect = 3e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 336 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 393
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 394 DATLRVWDIETGQCLHVLMGHVAAVRCVRYDGRR---VVSGAYDFMVKVWDPETETCLHT 450
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 451 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 506
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 507 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 535
>U72342-1|AAC51111.1| 410|Homo sapiens platelet activating factor
acetylhydrolase, brain isoform, 45 kDa subunit protein.
Length = 410
Score = 74.1 bits (174), Expect = 1e-12
Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 24/208 (11%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
+G +V+ + +K+++VQ+ ++ FTGH V +D I S S+D++V +W
Sbjct: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 262
Query: 155 ISTEERIANFNEHTDYIRAGAASPISP-------------------DIILSGSYDHTVKL 195
++T+E A EH + + +P S +LSGS D T+K+
Sbjct: 263 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKM 322
Query: 196 YDCRSNETIMT-VNHGSPVESTLFLPSGGIFI--SAGGTEIKVWDIFNGGKLLSNISQHH 252
+D + +MT V H + V LF SGG FI A ++VWD + + + ++ H
Sbjct: 323 WDVSTGMCLMTLVGHDNWVRGVLF-HSGGKFILSCADDKTLRVWD-YKNKRCMKTLNAHE 380
Query: 253 KTVTTLRLASNNSRLMSASLDRHVKIYD 280
VT+L +++ S+D+ VK+++
Sbjct: 381 HFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 71.3 bits (167), Expect = 8e-12
Identities = 46/163 (28%), Positives = 83/163 (50%), Gaps = 4/163 (2%)
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
+GH PV R F ++S S+D ++ +WD T + HTD ++ + S
Sbjct: 105 SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQ-DISFDHSGK 163
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFN 240
++ S S D T+KL+D + E I T++ H V S +P+G +SA + IK+W++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV-Q 222
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
G + + H + V +R + + + S S D+ V+++ V+T
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVAT 265
Score = 61.3 bits (142), Expect = 8e-09
Identities = 60/293 (20%), Positives = 126/293 (43%), Gaps = 25/293 (8%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F PV +A+ ++V+D T + + ++ F G+LL + + +K
Sbjct: 116 FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIK 175
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
L+D Q +R GH V + I+S S DK++ +W++ T + F H +
Sbjct: 176 LWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHRE 235
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLY-----DC----RSNETIMTVNHGSPVESTLFL- 219
++R + +I S S D TV+++ +C R +E ++ +P S +
Sbjct: 236 WVRMVRPNQ-DGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 294
Query: 220 --------PSG--GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
SG G F+ +G + IK+WD+ G L++ + H V + S +
Sbjct: 295 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG-HDNWVRGVLFHSGGKFI 353
Query: 268 MSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+S + D+ ++++D + + ++ + + S+ + + G +D + +
Sbjct: 354 LSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 406
Score = 59.7 bits (138), Expect = 3e-08
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G L++G + +K++DV + L GH V F I+S +DDK++ +WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
+ + N H ++ + +P +++GS D TVK+++CR
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAP-YVVTGSVDQTVKVWECR 410
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 3/123 (2%)
Query: 199 RSNETIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTT 257
R E H SPV +F P + +SA IKVWD + G + H +V
Sbjct: 97 RPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWD-YETGDFERTLKGHTDSVQD 155
Query: 258 LRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGI 316
+ + L S S D +K++D F+ + + + + S+AI + D + D
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKT 215
Query: 317 ISI 319
I +
Sbjct: 216 IKM 218
>L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 288
Score = 74.1 bits (174), Expect = 1e-12
Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 24/208 (11%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
+G +V+ + +K+++VQ+ ++ FTGH V +D I S S+D++V +W
Sbjct: 81 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 140
Query: 155 ISTEERIANFNEHTDYIRAGAASPISP-------------------DIILSGSYDHTVKL 195
++T+E A EH + + +P S +LSGS D T+K+
Sbjct: 141 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKM 200
Query: 196 YDCRSNETIMT-VNHGSPVESTLFLPSGGIFI--SAGGTEIKVWDIFNGGKLLSNISQHH 252
+D + +MT V H + V LF SGG FI A ++VWD + + + ++ H
Sbjct: 201 WDVSTGMCLMTXVGHDNWVRGVLF-HSGGKFILSCADDKTLRVWD-YKNKRCMKTLNAHE 258
Query: 253 KTVTTLRLASNNSRLMSASLDRHVKIYD 280
VT+L +++ S+D+ VK+++
Sbjct: 259 HFVTSLDFHKTAPYVVTGSVDQTVKVWE 286
Score = 59.3 bits (137), Expect = 3e-08
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G L++G + +K++DV + L GH V F I+S +DDK++ +WD
Sbjct: 186 GPFLLSGSRDKTIKMWDVSTGMCLMTXVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 245
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
+ + N H ++ + +P +++GS D TVK+++CR
Sbjct: 246 KNKRCMKTLNAHEHFVTSLDFHKTAP-YVVTGSVDQTVKVWECR 288
Score = 58.4 bits (135), Expect = 6e-08
Identities = 57/284 (20%), Positives = 123/284 (43%), Gaps = 25/284 (8%)
Query: 59 AATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNV 118
+A+ ++V+D T + + ++ F G+LL + + +KL+D Q
Sbjct: 3 SASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFEC 62
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
+R GH V + I+S S DK++ +W++ T + F H +++R +
Sbjct: 63 IRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQ 122
Query: 179 ISPDIILSGSYDHTVKLY-----DC----RSNETIMTVNHGSPVESTLFL---------P 220
+I S S D TV+++ +C R +E ++ +P S +
Sbjct: 123 -DGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKK 181
Query: 221 SG--GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHV 276
SG G F+ +G + IK+WD+ G L++ + H V + S ++S + D+ +
Sbjct: 182 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTXVG-HDNWVRGVLFHSGGKFILSCADDKTL 240
Query: 277 KIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+++D + + ++ + + S+ + + G +D + +
Sbjct: 241 RVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 284
Score = 56.0 bits (129), Expect = 3e-07
Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 4/169 (2%)
Query: 99 LVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTE 158
+V+ E+A +K++D ++ + R GHT V F + S S D ++ LWD
Sbjct: 1 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 60
Query: 159 ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTL 217
E I + H + + A P + D I+S S D T+K+++ ++ + T H V
Sbjct: 61 ECIRTMHGHDHNVSSVAIMP-NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR 119
Query: 218 FLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
G + S + ++VW + + + + +H V + A +S
Sbjct: 120 PNQDGTLIASCSNDQTVRVW-VVATKECKAELREHEHVVECISWAPESS 167
Score = 50.4 bits (115), Expect = 2e-05
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 184 ILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGT-EIKVWDIFNG 241
++S S D T+K++D + + T+ H V+ F SG + S IK+WD F G
Sbjct: 1 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWD-FQG 59
Query: 242 GKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
+ + + H V+++ + N ++SAS D+ +K+++V T
Sbjct: 60 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 101
>L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 74.1 bits (174), Expect = 1e-12
Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 24/208 (11%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
+G +V+ + +K+++VQ+ ++ FTGH V +D I S S+D++V +W
Sbjct: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 262
Query: 155 ISTEERIANFNEHTDYIRAGAASPISP-------------------DIILSGSYDHTVKL 195
++T+E A EH + + +P S +LSGS D T+K+
Sbjct: 263 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKM 322
Query: 196 YDCRSNETIMT-VNHGSPVESTLFLPSGGIFI--SAGGTEIKVWDIFNGGKLLSNISQHH 252
+D + +MT V H + V LF SGG FI A ++VWD + + + ++ H
Sbjct: 323 WDVSTGMCLMTLVGHDNWVRGVLF-HSGGKFILSCADDKTLRVWD-YKNKRCMKTLNAHE 380
Query: 253 KTVTTLRLASNNSRLMSASLDRHVKIYD 280
VT+L +++ S+D+ VK+++
Sbjct: 381 HFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 71.3 bits (167), Expect = 8e-12
Identities = 46/163 (28%), Positives = 83/163 (50%), Gaps = 4/163 (2%)
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
+GH PV R F ++S S+D ++ +WD T + HTD ++ + S
Sbjct: 105 SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQ-DISFDHSGK 163
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFN 240
++ S S D T+KL+D + E I T++ H V S +P+G +SA + IK+W++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV-Q 222
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
G + + H + V +R + + + S S D+ V+++ V+T
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVAT 265
Score = 61.3 bits (142), Expect = 8e-09
Identities = 60/293 (20%), Positives = 126/293 (43%), Gaps = 25/293 (8%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F PV +A+ ++V+D T + + ++ F G+LL + + +K
Sbjct: 116 FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIK 175
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
L+D Q +R GH V + I+S S DK++ +W++ T + F H +
Sbjct: 176 LWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHRE 235
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLY-----DC----RSNETIMTVNHGSPVESTLFL- 219
++R + +I S S D TV+++ +C R +E ++ +P S +
Sbjct: 236 WVRMVRPNQ-DGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 294
Query: 220 --------PSG--GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
SG G F+ +G + IK+WD+ G L++ + H V + S +
Sbjct: 295 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG-HDNWVRGVLFHSGGKFI 353
Query: 268 MSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+S + D+ ++++D + + ++ + + S+ + + G +D + +
Sbjct: 354 LSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 406
Score = 59.7 bits (138), Expect = 3e-08
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G L++G + +K++DV + L GH V F I+S +DDK++ +WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
+ + N H ++ + +P +++GS D TVK+++CR
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAP-YVVTGSVDQTVKVWECR 410
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 3/123 (2%)
Query: 199 RSNETIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTT 257
R E H SPV +F P + +SA IKVWD + G + H +V
Sbjct: 97 RPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWD-YETGDFERTLKGHTDSVQD 155
Query: 258 LRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGI 316
+ + L S S D +K++D F+ + + + + S+AI + D + D
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKT 215
Query: 317 ISI 319
I +
Sbjct: 216 IKM 218
>L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 74.1 bits (174), Expect = 1e-12
Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 24/208 (11%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
+G +V+ + +K+++VQ+ ++ FTGH V +D I S S+D++V +W
Sbjct: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 262
Query: 155 ISTEERIANFNEHTDYIRAGAASPISP-------------------DIILSGSYDHTVKL 195
++T+E A EH + + +P S +LSGS D T+K+
Sbjct: 263 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKM 322
Query: 196 YDCRSNETIMT-VNHGSPVESTLFLPSGGIFI--SAGGTEIKVWDIFNGGKLLSNISQHH 252
+D + +MT V H + V LF SGG FI A ++VWD + + + ++ H
Sbjct: 323 WDVSTGMCLMTLVGHDNWVRGVLF-HSGGKFILSCADDKTLRVWD-YKNKRCMKTLNAHE 380
Query: 253 KTVTTLRLASNNSRLMSASLDRHVKIYD 280
VT+L +++ S+D+ VK+++
Sbjct: 381 HFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 71.3 bits (167), Expect = 8e-12
Identities = 46/163 (28%), Positives = 83/163 (50%), Gaps = 4/163 (2%)
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
+GH PV R F ++S S+D ++ +WD T + HTD ++ + S
Sbjct: 105 SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQ-DISFDHSGK 163
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFN 240
++ S S D T+KL+D + E I T++ H V S +P+G +SA + IK+W++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV-Q 222
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
G + + H + V +R + + + S S D+ V+++ V+T
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVAT 265
Score = 61.3 bits (142), Expect = 8e-09
Identities = 60/293 (20%), Positives = 126/293 (43%), Gaps = 25/293 (8%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F PV +A+ ++V+D T + + ++ F G+LL + + +K
Sbjct: 116 FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIK 175
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
L+D Q +R GH V + I+S S DK++ +W++ T + F H +
Sbjct: 176 LWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHRE 235
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLY-----DC----RSNETIMTVNHGSPVESTLFL- 219
++R + +I S S D TV+++ +C R +E ++ +P S +
Sbjct: 236 WVRMVRPNQ-DGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 294
Query: 220 --------PSG--GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
SG G F+ +G + IK+WD+ G L++ + H V + S +
Sbjct: 295 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG-HDNWVRGVLFHSGGKFI 353
Query: 268 MSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+S + D+ ++++D + + ++ + + S+ + + G +D + +
Sbjct: 354 LSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 406
Score = 59.7 bits (138), Expect = 3e-08
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G L++G + +K++DV + L GH V F I+S +DDK++ +WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
+ + N H ++ + +P +++GS D TVK+++CR
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAP-YVVTGSVDQTVKVWECR 410
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 3/123 (2%)
Query: 199 RSNETIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTT 257
R E H SPV +F P + +SA IKVWD + G + H +V
Sbjct: 97 RPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWD-YETGDFERTLKGHTDSVQD 155
Query: 258 LRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGI 316
+ + L S S D +K++D F+ + + + + S+AI + D + D
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKT 215
Query: 317 ISI 319
I +
Sbjct: 216 IKM 218
>BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 506 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 563
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 564 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 620
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 621 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 679
Query: 265 SRLMSA 270
++L+ A
Sbjct: 680 TKLVCA 685
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 386 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 443
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 444 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 501 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 556
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 557 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 605
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 422 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 479
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 480 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 536
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 537 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 592
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 593 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 621
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 523 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 580
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 581 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 638
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 639 TSSDDGTVKLWDLKTGEFI 657
>BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 506 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 563
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 564 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 620
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 621 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 679
Query: 265 SRLMSA 270
++L+ A
Sbjct: 680 TKLVCA 685
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 386 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 443
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 444 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 501 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 556
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 557 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 605
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 422 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 479
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 480 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 536
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 537 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 592
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 593 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 621
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 523 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 580
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 581 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 638
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 639 TSSDDGTVKLWDLKTGEFI 657
>BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating factor
acetylhydrolase, isoform Ib, alpha subunit 45kDa
protein.
Length = 410
Score = 74.1 bits (174), Expect = 1e-12
Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 24/208 (11%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
+G +V+ + +K+++VQ+ ++ FTGH V +D I S S+D++V +W
Sbjct: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 262
Query: 155 ISTEERIANFNEHTDYIRAGAASPISP-------------------DIILSGSYDHTVKL 195
++T+E A EH + + +P S +LSGS D T+K+
Sbjct: 263 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKM 322
Query: 196 YDCRSNETIMT-VNHGSPVESTLFLPSGGIFI--SAGGTEIKVWDIFNGGKLLSNISQHH 252
+D + +MT V H + V LF SGG FI A ++VWD + + + ++ H
Sbjct: 323 WDVSTGMCLMTLVGHDNWVRGVLF-HSGGKFILSCADDKTLRVWD-YKNKRCMKTLNAHE 380
Query: 253 KTVTTLRLASNNSRLMSASLDRHVKIYD 280
VT+L +++ S+D+ VK+++
Sbjct: 381 HFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 71.3 bits (167), Expect = 8e-12
Identities = 46/163 (28%), Positives = 83/163 (50%), Gaps = 4/163 (2%)
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
+GH PV R F ++S S+D ++ +WD T + HTD ++ + S
Sbjct: 105 SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQ-DISFDHSGK 163
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFN 240
++ S S D T+KL+D + E I T++ H V S +P+G +SA + IK+W++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV-Q 222
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
G + + H + V +R + + + S S D+ V+++ V+T
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVAT 265
Score = 61.3 bits (142), Expect = 8e-09
Identities = 60/293 (20%), Positives = 126/293 (43%), Gaps = 25/293 (8%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F PV +A+ ++V+D T + + ++ F G+LL + + +K
Sbjct: 116 FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIK 175
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
L+D Q +R GH V + I+S S DK++ +W++ T + F H +
Sbjct: 176 LWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHRE 235
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLY-----DC----RSNETIMTVNHGSPVESTLFL- 219
++R + +I S S D TV+++ +C R +E ++ +P S +
Sbjct: 236 WVRMVRPNQ-DGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 294
Query: 220 --------PSG--GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
SG G F+ +G + IK+WD+ G L++ + H V + S +
Sbjct: 295 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG-HDNWVRGVLFHSGGKFI 353
Query: 268 MSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+S + D+ ++++D + + ++ + + S+ + + G +D + +
Sbjct: 354 LSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 406
Score = 59.7 bits (138), Expect = 3e-08
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G L++G + +K++DV + L GH V F I+S +DDK++ +WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
+ + N H ++ + +P +++GS D TVK+++CR
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAP-YVVTGSVDQTVKVWECR 410
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 3/123 (2%)
Query: 199 RSNETIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTT 257
R E H SPV +F P + +SA IKVWD + G + H +V
Sbjct: 97 RPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWD-YETGDFERTLKGHTDSVQD 155
Query: 258 LRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGI 316
+ + L S S D +K++D F+ + + + + S+AI + D + D
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKT 215
Query: 317 ISI 319
I +
Sbjct: 216 IKM 218
>BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein.
Length = 452
Score = 74.1 bits (174), Expect = 1e-12
Identities = 56/218 (25%), Positives = 98/218 (44%), Gaps = 5/218 (2%)
Query: 70 DPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHT-GP 128
DP++K+ K +S A F D L++G + VKL+D +V+R F P
Sbjct: 114 DPLSKIPFKILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAP 173
Query: 129 VHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGS 188
V T D ++I+ S DK+V WD+ T + + T +I + SP ++
Sbjct: 174 VVECSITGDSSRVIAASYDKTVRAWDLETGKLLWKVRYDT-FIVSCKFSPDGKYVVSGFD 232
Query: 189 YDHTVKLYDCRSNETIMTV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLL 245
DH + + D + T+ + +H + S F P S IK+WD+ + LL
Sbjct: 233 VDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLL 292
Query: 246 SNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
+ H ++ + L ++S D+++KI++V T
Sbjct: 293 TITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHT 330
Score = 66.5 bits (155), Expect = 2e-10
Identities = 44/201 (21%), Positives = 95/201 (47%), Gaps = 13/201 (6%)
Query: 92 FRADGRLLVAGIE-EAAVKLFDVQSKNVLRVFTGH-TGPVHRTFFTKDQLKIISYSDDKS 149
F DG+ +V+G + + + + D ++ + V H T + F D ++ S S D+
Sbjct: 220 FSPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRC 279
Query: 150 VGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE------- 202
+ +WD++++ + + + S + + S+D +K+++ + E
Sbjct: 280 IKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCGAC 339
Query: 203 -TIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRL 260
T+M + GS V S F IS G + +WD+ G + LS + H+ V + +
Sbjct: 340 VTLMQGHEGS-VSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLS-LKGHNDWVMDVAI 397
Query: 261 ASNNSRLMSASLDRHVKIYDV 281
++N ++SAS DR ++++++
Sbjct: 398 SNNKKWILSASKDRTMRLWNI 418
Score = 62.1 bits (144), Expect = 5e-09
Identities = 54/262 (20%), Positives = 112/262 (42%), Gaps = 13/262 (4%)
Query: 32 KLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGC 91
K+ +L A+ F + + + V+++DPV V ++ +A C
Sbjct: 118 KIPFKILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVEC 177
Query: 92 -FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
D ++A + V+ +D+++ +L T V F + + + D +
Sbjct: 178 SITGDSSRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGI 237
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDI--ILSGSYDHTVKLYDCRSNETIMTVN 208
+ D ++ +H + R+ + PD + S S D +K++D S T++T+
Sbjct: 238 CIMDAENITTVSVIKDH--HTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTIT 295
Query: 209 --HGSPVESTLFLPSGGIFI-SAGGTEIKVWDIFNG-----GKLLSNISQHHKTVTTLRL 260
H + + + F SG S+ +K+W++ G G ++ + H +V++
Sbjct: 296 KAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHF 355
Query: 261 ASNNSRLMSASLDRHVKIYDVS 282
A ++S L+S DR V I+DV+
Sbjct: 356 ARDSSFLISGGFDRTVAIWDVA 377
Score = 50.8 bits (116), Expect = 1e-05
Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 8/149 (5%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGC-FRADGRLLVAGIEEAAVKLFDVQS---KNV--- 118
++++D ++ I+K A C F G L + +K+++V + +N
Sbjct: 280 IKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCGAC 339
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
+ + GH G V F +D +IS D++V +WD++ R + H D++ A S
Sbjct: 340 VTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISN 399
Query: 179 ISPDIILSGSYDHTVKLYDCRSNETIMTV 207
+ ILS S D T++L++ + I V
Sbjct: 400 -NKKWILSASKDRTMRLWNIEEIDEIPLV 427
>AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4
protein.
Length = 707
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 506 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 563
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 564 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 620
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 621 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 679
Query: 265 SRLMSA 270
++L+ A
Sbjct: 680 TKLVCA 685
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 386 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 443
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 444 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 501 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 556
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 557 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 605
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 422 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 479
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 480 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 536
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 537 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 592
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 593 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 621
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 523 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 580
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 581 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 638
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 639 TSSDDGTVKLWDLKTGEFI 657
>AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7
protein.
Length = 627
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 426 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 483
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 484 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 540
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 541 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 599
Query: 265 SRLMSA 270
++L+ A
Sbjct: 600 TKLVCA 605
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 306 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 363
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 364 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 420
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 421 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 476
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 477 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 525
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 342 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 399
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 400 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 456
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 457 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 512
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 513 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 541
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 443 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 500
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 501 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 558
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 559 TSSDDGTVKLWDLKTGEFI 577
>AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10
protein.
Length = 589
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 388 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 445
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 446 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 502
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 503 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 561
Query: 265 SRLMSA 270
++L+ A
Sbjct: 562 TKLVCA 567
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 268 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 325
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 326 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 382
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 383 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 438
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 439 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 487
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 304 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 361
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 362 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 418
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 419 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 474
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 475 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 503
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 405 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 462
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 463 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 520
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 521 TSSDDGTVKLWDLKTGEFI 539
>AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 627
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 426 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 483
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 484 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 540
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 541 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 599
Query: 265 SRLMSA 270
++L+ A
Sbjct: 600 TKLVCA 605
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 306 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 363
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 364 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 420
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 421 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 476
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 477 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 525
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 342 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 399
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 400 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 456
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 457 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 512
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 513 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 541
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 443 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 500
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 501 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 558
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 559 TSSDDGTVKLWDLKTGEFI 577
>AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens
cDNA FLJ16579 fis, clone TESTI2049956, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 472
Score = 74.1 bits (174), Expect = 1e-12
Identities = 56/218 (25%), Positives = 98/218 (44%), Gaps = 5/218 (2%)
Query: 70 DPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHT-GP 128
DP++K+ K +S A F D L++G + VKL+D +V+R F P
Sbjct: 88 DPLSKIPFKILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAP 147
Query: 129 VHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGS 188
V T D ++I+ S DK+V WD+ T + + T +I + SP ++
Sbjct: 148 VVECSITGDSSRVIAASYDKTVRAWDLETGKLLWKVRYDT-FIVSCKFSPDGKYVVSGFD 206
Query: 189 YDHTVKLYDCRSNETIMTV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLL 245
DH + + D + T+ + +H + S F P S IK+WD+ + LL
Sbjct: 207 VDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLL 266
Query: 246 SNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
+ H ++ + L ++S D+++KI++V T
Sbjct: 267 TITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHT 304
Score = 66.5 bits (155), Expect = 2e-10
Identities = 44/201 (21%), Positives = 95/201 (47%), Gaps = 13/201 (6%)
Query: 92 FRADGRLLVAGIE-EAAVKLFDVQSKNVLRVFTGH-TGPVHRTFFTKDQLKIISYSDDKS 149
F DG+ +V+G + + + + D ++ + V H T + F D ++ S S D+
Sbjct: 194 FSPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRC 253
Query: 150 VGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE------- 202
+ +WD++++ + + + S + + S+D +K+++ + E
Sbjct: 254 IKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGAC 313
Query: 203 -TIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRL 260
T+M + GS V S F IS G + +WD+ G + LS + H+ V + +
Sbjct: 314 VTLMQGHEGS-VSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLS-LKGHNDWVMDVAI 371
Query: 261 ASNNSRLMSASLDRHVKIYDV 281
++N ++SAS DR ++++++
Sbjct: 372 SNNKKWILSASKDRTMRLWNI 392
Score = 62.1 bits (144), Expect = 5e-09
Identities = 54/262 (20%), Positives = 112/262 (42%), Gaps = 13/262 (4%)
Query: 32 KLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGC 91
K+ +L A+ F + + + V+++DPV V ++ +A C
Sbjct: 92 KIPFKILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVEC 151
Query: 92 -FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
D ++A + V+ +D+++ +L T V F + + + D +
Sbjct: 152 SITGDSSRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGI 211
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDI--ILSGSYDHTVKLYDCRSNETIMTVN 208
+ D ++ +H + R+ + PD + S S D +K++D S T++T+
Sbjct: 212 CIMDAENITTVSVIKDH--HTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTIT 269
Query: 209 --HGSPVESTLFLPSGGIFI-SAGGTEIKVWDIFNG-----GKLLSNISQHHKTVTTLRL 260
H + + + F SG S+ +K+W++ G G ++ + H +V++
Sbjct: 270 KAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGACVTLMQGHEGSVSSCHF 329
Query: 261 ASNNSRLMSASLDRHVKIYDVS 282
A ++S L+S DR V I+DV+
Sbjct: 330 ARDSSFLISGGFDRTVAIWDVA 351
Score = 50.8 bits (116), Expect = 1e-05
Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 8/149 (5%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGC-FRADGRLLVAGIEEAAVKLFDVQS---KN---V 118
++++D ++ I+K A C F G L + +K+++V + +N
Sbjct: 254 IKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGAC 313
Query: 119 LRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
+ + GH G V F +D +IS D++V +WD++ R + H D++ A S
Sbjct: 314 VTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISN 373
Query: 179 ISPDIILSGSYDHTVKLYDCRSNETIMTV 207
+ ILS S D T++L++ + I V
Sbjct: 374 -NKKWILSASKDRTMRLWNIEEIDEIPLV 401
>AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ11071 fis, clone PLACE1004937, moderately
similar to SEL-10 PROTEIN. ).
Length = 553
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 352 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 409
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 410 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 466
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 467 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 525
Query: 265 SRLMSA 270
++L+ A
Sbjct: 526 TKLVCA 531
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 232 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 289
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 290 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 346
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 347 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 402
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 403 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 451
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 268 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 325
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 326 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 382
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 383 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 438
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 439 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 467
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 369 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 426
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 427 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 484
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 485 TSSDDGTVKLWDLKTGEFI 503
>AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form
protein.
Length = 627
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 426 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 483
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 484 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 540
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 541 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 599
Query: 265 SRLMSA 270
++L+ A
Sbjct: 600 TKLVCA 605
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 306 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 363
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 364 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 420
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 421 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 476
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 477 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 525
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 342 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 399
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 400 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 456
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 457 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 512
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 513 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 541
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 443 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 500
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 501 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 558
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 559 TSSDDGTVKLWDLKTGEFI 577
>AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form
protein.
Length = 707
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 506 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 563
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 564 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 620
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 621 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 679
Query: 265 SRLMSA 270
++L+ A
Sbjct: 680 TKLVCA 685
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 386 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 443
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 444 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 501 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 556
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 557 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 605
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 422 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 479
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 480 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 536
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 537 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 592
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 593 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 621
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 523 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 580
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 581 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 638
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 639 TSSDDGTVKLWDLKTGEFI 657
>AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating factor
acetyl hydrolase isoform Ib alpha subunit protein.
Length = 410
Score = 74.1 bits (174), Expect = 1e-12
Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 24/208 (11%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
+G +V+ + +K+++VQ+ ++ FTGH V +D I S S+D++V +W
Sbjct: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 262
Query: 155 ISTEERIANFNEHTDYIRAGAASPISP-------------------DIILSGSYDHTVKL 195
++T+E A EH + + +P S +LSGS D T+K+
Sbjct: 263 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKM 322
Query: 196 YDCRSNETIMT-VNHGSPVESTLFLPSGGIFI--SAGGTEIKVWDIFNGGKLLSNISQHH 252
+D + +MT V H + V LF SGG FI A ++VWD + + + ++ H
Sbjct: 323 WDVSTGMCLMTLVGHDNWVRGVLF-HSGGKFILSCADDKTLRVWD-YKNKRCMKTLNAHE 380
Query: 253 KTVTTLRLASNNSRLMSASLDRHVKIYD 280
VT+L +++ S+D+ VK+++
Sbjct: 381 HFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 71.3 bits (167), Expect = 8e-12
Identities = 46/163 (28%), Positives = 83/163 (50%), Gaps = 4/163 (2%)
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
+GH PV R F ++S S+D ++ +WD T + HTD ++ + S
Sbjct: 105 SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQ-DISFDHSGK 163
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFN 240
++ S S D T+KL+D + E I T++ H V S +P+G +SA + IK+W++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV-Q 222
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
G + + H + V +R + + + S S D+ V+++ V+T
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVAT 265
Score = 61.3 bits (142), Expect = 8e-09
Identities = 60/293 (20%), Positives = 126/293 (43%), Gaps = 25/293 (8%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F PV +A+ ++V+D T + + ++ F G+LL + + +K
Sbjct: 116 FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIK 175
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
L+D Q +R GH V + I+S S DK++ +W++ T + F H +
Sbjct: 176 LWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHRE 235
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLY-----DC----RSNETIMTVNHGSPVESTLFL- 219
++R + +I S S D TV+++ +C R +E ++ +P S +
Sbjct: 236 WVRMVRPNQ-DGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 294
Query: 220 --------PSG--GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
SG G F+ +G + IK+WD+ G L++ + H V + S +
Sbjct: 295 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG-HDNWVRGVLFHSGGKFI 353
Query: 268 MSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+S + D+ ++++D + + ++ + + S+ + + G +D + +
Sbjct: 354 LSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 406
Score = 59.7 bits (138), Expect = 3e-08
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G L++G + +K++DV + L GH V F I+S +DDK++ +WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
+ + N H ++ + +P +++GS D TVK+++CR
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAP-YVVTGSVDQTVKVWECR 410
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 3/123 (2%)
Query: 199 RSNETIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTT 257
R E H SPV +F P + +SA IKVWD + G + H +V
Sbjct: 97 RPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWD-YETGDFERTLKGHTDSVQD 155
Query: 258 LRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGI 316
+ + L S S D +K++D F+ + + + + S+AI + D + D
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKT 215
Query: 317 ISI 319
I +
Sbjct: 216 IKM 218
>AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30
protein.
Length = 561
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 360 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 417
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 418 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 474
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 475 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 533
Query: 265 SRLMSA 270
++L+ A
Sbjct: 534 TKLVCA 539
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 240 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 297
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 298 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 354
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 355 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 410
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 411 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 459
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 276 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 333
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 334 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 390
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 391 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 446
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 447 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 475
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 377 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 434
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 435 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 492
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 493 TSSDDGTVKLWDLKTGEFI 511
>AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 74.1 bits (174), Expect = 1e-12
Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 24/208 (11%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
+G +V+ + +K+++VQ+ ++ FTGH V +D I S S+D++V +W
Sbjct: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 262
Query: 155 ISTEERIANFNEHTDYIRAGAASPISP-------------------DIILSGSYDHTVKL 195
++T+E A EH + + +P S +LSGS D T+K+
Sbjct: 263 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKM 322
Query: 196 YDCRSNETIMT-VNHGSPVESTLFLPSGGIFI--SAGGTEIKVWDIFNGGKLLSNISQHH 252
+D + +MT V H + V LF SGG FI A ++VWD + + + ++ H
Sbjct: 323 WDVSTGMCLMTLVGHDNWVRGVLF-HSGGKFILSCADDKTLRVWD-YKNKRCMKTLNAHE 380
Query: 253 KTVTTLRLASNNSRLMSASLDRHVKIYD 280
VT+L +++ S+D+ VK+++
Sbjct: 381 HFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 69.7 bits (163), Expect = 2e-11
Identities = 46/163 (28%), Positives = 82/163 (50%), Gaps = 4/163 (2%)
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
+GH PV R F ++S S+D ++ +WD T + HTD ++ + S
Sbjct: 105 SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQ-DISFDHSGK 163
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFN 240
++ S S D T+KL D + E I T++ H V S +P+G +SA + IK+W++
Sbjct: 164 LLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV-Q 222
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
G + + H + V +R + + + S S D+ V+++ V+T
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVAT 265
Score = 59.7 bits (138), Expect = 3e-08
Identities = 60/293 (20%), Positives = 125/293 (42%), Gaps = 25/293 (8%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F PV +A+ ++V+D T + + ++ F G+LL + + +K
Sbjct: 116 FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIK 175
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
L D Q +R GH V + I+S S DK++ +W++ T + F H +
Sbjct: 176 LRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHRE 235
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLY-----DC----RSNETIMTVNHGSPVESTLFL- 219
++R + +I S S D TV+++ +C R +E ++ +P S +
Sbjct: 236 WVRMVRPNQ-DGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 294
Query: 220 --------PSG--GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
SG G F+ +G + IK+WD+ G L++ + H V + S +
Sbjct: 295 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG-HDNWVRGVLFHSGGKFI 353
Query: 268 MSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+S + D+ ++++D + + ++ + + S+ + + G +D + +
Sbjct: 354 LSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 406
Score = 59.7 bits (138), Expect = 3e-08
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G L++G + +K++DV + L GH V F I+S +DDK++ +WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
+ + N H ++ + +P +++GS D TVK+++CR
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAP-YVVTGSVDQTVKVWECR 410
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 3/123 (2%)
Query: 199 RSNETIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTT 257
R E H SPV +F P + +SA IKVWD + G + H +V
Sbjct: 97 RPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWD-YETGDFERTLKGHTDSVQD 155
Query: 258 LRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGI 316
+ + L S S D +K+ D F+ + + + + S+AI + D + D
Sbjct: 156 ISFDHSGKLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKT 215
Query: 317 ISI 319
I +
Sbjct: 216 IKM 218
>AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 74.1 bits (174), Expect = 1e-12
Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 24/208 (11%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
+G +V+ + +K+++VQ+ ++ FTGH V +D I S S+D++V +W
Sbjct: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 262
Query: 155 ISTEERIANFNEHTDYIRAGAASPISP-------------------DIILSGSYDHTVKL 195
++T+E A EH + + +P S +LSGS D T+K+
Sbjct: 263 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKM 322
Query: 196 YDCRSNETIMT-VNHGSPVESTLFLPSGGIFI--SAGGTEIKVWDIFNGGKLLSNISQHH 252
+D + +MT V H + V LF SGG FI A ++VWD + + + ++ H
Sbjct: 323 WDVSTGMCLMTLVGHDNWVRGVLF-HSGGKFILSCADDKTLRVWD-YKNKRCMKTLNAHE 380
Query: 253 KTVTTLRLASNNSRLMSASLDRHVKIYD 280
VT+L +++ S+D+ VK+++
Sbjct: 381 HFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 71.3 bits (167), Expect = 8e-12
Identities = 46/163 (28%), Positives = 83/163 (50%), Gaps = 4/163 (2%)
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
+GH PV R F ++S S+D ++ +WD T + HTD ++ + S
Sbjct: 105 SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQ-DISFDHSGK 163
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFN 240
++ S S D T+KL+D + E I T++ H V S +P+G +SA + IK+W++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV-Q 222
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
G + + H + V +R + + + S S D+ V+++ V+T
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVAT 265
Score = 61.3 bits (142), Expect = 8e-09
Identities = 60/293 (20%), Positives = 126/293 (43%), Gaps = 25/293 (8%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F PV +A+ ++V+D T + + ++ F G+LL + + +K
Sbjct: 116 FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIK 175
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
L+D Q +R GH V + I+S S DK++ +W++ T + F H +
Sbjct: 176 LWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHRE 235
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLY-----DC----RSNETIMTVNHGSPVESTLFL- 219
++R + +I S S D TV+++ +C R +E ++ +P S +
Sbjct: 236 WVRMVRPNQ-DGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 294
Query: 220 --------PSG--GIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
SG G F+ +G + IK+WD+ G L++ + H V + S +
Sbjct: 295 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG-HDNWVRGVLFHSGGKFI 353
Query: 268 MSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+S + D+ ++++D + + ++ + + S+ + + G +D + +
Sbjct: 354 LSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 406
Score = 59.7 bits (138), Expect = 3e-08
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G L++G + +K++DV + L GH V F I+S +DDK++ +WD
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
+ + N H ++ + +P +++GS D TVK+++CR
Sbjct: 368 KNKRCMKTLNAHEHFVTSLDFHKTAP-YVVTGSVDQTVKVWECR 410
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 3/123 (2%)
Query: 199 RSNETIMTVNHGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTT 257
R E H SPV +F P + +SA IKVWD + G + H +V
Sbjct: 97 RPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWD-YETGDFERTLKGHTDSVQD 155
Query: 258 LRLASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGI 316
+ + L S S D +K++D F+ + + + + S+AI + D + D
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKT 215
Query: 317 ISI 319
I +
Sbjct: 216 IKM 218
>AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 624
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + DGR +V+G + VK++D +++ L GHT V+ F D + ++S S D S+
Sbjct: 423 CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSI 480
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV--- 207
+WD+ T I H + + +I++SG+ D TVK++D ++ + + T+
Sbjct: 481 RVWDVETGNCIHTLTGHQSLT---SGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGP 537
Query: 208 -NHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGG--KLLSNISQHHKTVTTLRLASNN 264
H S V F + I S GT +K+WD+ G + L + R+ ++N
Sbjct: 538 NKHQSAVTCLQFNKNFVITSSDDGT-VKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASN 596
Query: 265 SRLMSA 270
++L+ A
Sbjct: 597 TKLVCA 602
Score = 73.7 bits (173), Expect = 1e-12
Identities = 57/230 (24%), Positives = 108/230 (46%), Gaps = 11/230 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + G +V+G ++ +K++ + LR GHTG V + +D + IIS S D+++
Sbjct: 303 CLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM-RDNI-IISGSTDRTL 360
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNH 209
+W+ T E I HT +R + ++SGS D T++++D + + + + + H
Sbjct: 361 KVWNAETGECIHTLYGHTSTVR---CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 417
Query: 210 GSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ V + + A +KVWD L + H V +L+ + ++S
Sbjct: 418 VAAVRCVQY-DGRRVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVS 473
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDGIISI 319
SLD ++++DV T +H + ++ S + D+IL G D + I
Sbjct: 474 GSLDTSIRVWDVETGNCIHTLTGHQSLTS-GMELKDNILVSGNADSTVKI 522
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/211 (25%), Positives = 103/211 (48%), Gaps = 16/211 (7%)
Query: 89 GGCFRADGR--LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
GG + + R ++++G + +K+++ ++ + GHT V R ++ +++S S
Sbjct: 339 GGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV-RCMHLHEK-RVVSGSR 396
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D ++ +WDI T + + H +R ++SG+YD VK++D + + T
Sbjct: 397 DATLRVWDIETGQCLHVLMGHVAAVRC---VQYDGRRVVSGAYDFMVKVWDPETETCLHT 453
Query: 207 VN-HGSPVESTLFLPSGGIFISAGG--TEIKVWDIFNGGKLLSNISQHHKTVTTLRLASN 263
+ H + V S F GI + +G T I+VWD+ G + ++ H + + L N
Sbjct: 454 LQGHTNRVYSLQF---DGIHVVSGSLDTSIRVWDV-ETGNCIHTLTGHQSLTSGMELKDN 509
Query: 264 NSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
L+S + D VKI+D+ T + + + PN
Sbjct: 510 I--LVSGNADSTVKIWDIKTGQCLQTLQGPN 538
Score = 58.8 bits (136), Expect = 4e-08
Identities = 36/139 (25%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGH 125
V+V+DP T+ + Y F DG +V+G + +++++DV++ N + TGH
Sbjct: 440 VKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH 497
Query: 126 TGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL 185
+ KD + ++S + D +V +WDI T + + + A + + ++
Sbjct: 498 QS-LTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVI 555
Query: 186 SGSYDHTVKLYDCRSNETI 204
+ S D TVKL+D ++ E I
Sbjct: 556 TSSDDGTVKLWDLKTGEFI 574
>X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer complex
protein.
Length = 906
Score = 72.9 bits (171), Expect = 3e-12
Identities = 65/326 (19%), Positives = 139/326 (42%), Gaps = 11/326 (3%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
+D P EP+ A+ + V V++ T+ + K F A +V G ++
Sbjct: 21 VDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQ 80
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN-FNE 166
+++F+ + + +F H+ + Q I++ SDD + LWD + + F
Sbjct: 81 IRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEG 140
Query: 167 HTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGG--I 224
HT Y+ +P + S S D T+K++ S+ T+ + + SGG
Sbjct: 141 HTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKP 200
Query: 225 FISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVS 282
++ +G + +K+WD + + + H + V+ +++ S D V+I+ S
Sbjct: 201 YLISGADDRLVKIWD-YQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSS 259
Query: 283 TFKVVHNIDF-PNAILSMAISEHDDILTVGMMDGIISIR-KREEPVRQSEKRKNLLKFIP 340
T+++ +++ + +A + + +G +G I ++ REEP + K I
Sbjct: 260 TYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIVKLGREEPAMSMDANG---KIIW 316
Query: 341 DHTSQTKADTVEVANEVKINKKQKLP 366
S+ + ++ + +I ++LP
Sbjct: 317 AKHSEVQQANLKAMGDAEIKDGERLP 342
>BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein complex,
subunit beta 2 (beta prime) protein.
Length = 906
Score = 72.9 bits (171), Expect = 3e-12
Identities = 65/326 (19%), Positives = 139/326 (42%), Gaps = 11/326 (3%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
+D P EP+ A+ + V V++ T+ + K F A +V G ++
Sbjct: 21 VDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQ 80
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIAN-FNE 166
+++F+ + + +F H+ + Q I++ SDD + LWD + + F
Sbjct: 81 IRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEG 140
Query: 167 HTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGG--I 224
HT Y+ +P + S S D T+K++ S+ T+ + + SGG
Sbjct: 141 HTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKP 200
Query: 225 FISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVS 282
++ +G + +K+WD + + + H + V+ +++ S D V+I+ S
Sbjct: 201 YLISGADDRLVKIWD-YQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSS 259
Query: 283 TFKVVHNIDF-PNAILSMAISEHDDILTVGMMDGIISIR-KREEPVRQSEKRKNLLKFIP 340
T+++ +++ + +A + + +G +G I ++ REEP + K I
Sbjct: 260 TYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIVKLGREEPAMSMDANG---KIIW 316
Query: 341 DHTSQTKADTVEVANEVKINKKQKLP 366
S+ + ++ + +I ++LP
Sbjct: 317 AKHSEVQQANLKAMGDAEIKDGERLP 342
>BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69
protein.
Length = 415
Score = 72.1 bits (169), Expect = 4e-12
Identities = 58/228 (25%), Positives = 99/228 (43%), Gaps = 6/228 (2%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQ-LKIISYSDDKSVGLWD 154
G + G + KL+D S L GH V+ F KI + S DK+ LW
Sbjct: 104 GSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWS 163
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ T + F HT I + +P S ++ +GS D T KL+D ++ E + T+ H + +
Sbjct: 164 VETGKCYHTFRGHTAEIVCLSFNPQS-TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEI 222
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL 272
S F SG I+ + VWD G K ++ + H +++ + S +++ S+
Sbjct: 223 ISLSFNTSGDRIITGSFDHTVVVWDADTGRK-VNILIGHCAEISSASFNWDCSLILTGSM 281
Query: 273 DRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
D+ K++D + K V + + IL ++ DG I
Sbjct: 282 DKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARI 329
Score = 68.5 bits (160), Expect = 5e-11
Identities = 45/198 (22%), Positives = 85/198 (42%), Gaps = 4/198 (2%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G + G + KL+ V++ F GHT + F + + S D + LWDI
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVE 214
E + H+ I + S D I++GS+DHTV ++D + + + + H + +
Sbjct: 207 QNGEEVYTLRGHSAEI-ISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 215 STLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLD 273
S F + ++ K+WD N GK ++ ++ H + + +AS D
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATN-GKCVATLTGHDDEILDSCFDYTGKLIATASAD 324
Query: 274 RHVKIYDVSTFKVVHNID 291
+I+ +T K + ++
Sbjct: 325 GTARIFSAATRKCIAKLE 342
Score = 68.1 bits (159), Expect = 7e-11
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 7/232 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F L+ G + KL+D+Q+ + GH+ + F +II+ S D +V
Sbjct: 185 FNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVV 244
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
+WD T ++ H I + A+ +IL+GS D T KL+D + + + T+ H
Sbjct: 245 VWDADTGRKVNILIGHCAEI-SSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHD 303
Query: 211 SPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + F +G + SA GT +++ K ++ + H ++ + + L+
Sbjct: 304 DEILDSCFDYTGKLIATASADGT-ARIFSAAT-RKCIAKLEGHEGEISKISFNPQGNHLL 361
Query: 269 SASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+ S D+ +I+D T + + ++ + I S A + +I+ G D I
Sbjct: 362 TGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRI 413
Score = 66.9 bits (156), Expect = 2e-10
Identities = 49/200 (24%), Positives = 90/200 (45%), Gaps = 4/200 (2%)
Query: 118 VLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAAS 177
+ +V H P+ K I+ S D++ LWD ++ E + H + + A A +
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAG-GTEIKV 235
D I +GS+D T KL+ + + T H + + F P + + T K+
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNA 295
WDI NG ++ + + H + +L ++ R+++ S D V ++D T + V+ + A
Sbjct: 204 WDIQNGEEVYT-LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCA 262
Query: 296 ILSMAISEHD-DILTVGMMD 314
+S A D ++ G MD
Sbjct: 263 EISSASFNWDCSLILTGSMD 282
Score = 54.0 bits (124), Expect = 1e-06
Identities = 37/190 (19%), Positives = 78/190 (41%), Gaps = 4/190 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G ++ G + V ++D + + + GH + F D I++ S DK+
Sbjct: 227 FNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCK 286
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
LWD + + +A H D I + + +I + S D T +++ + + I + H
Sbjct: 287 LWDATNGKCVATLTGHDDEI-LDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 211 SPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ F P G ++ + ++WD G+ L + H + + + +++
Sbjct: 346 GEISKISFNPQGNHLLTGSSDKTARIWDA-QTGQCLQVLEGHTDEIFSCAFNYKGNIVIT 404
Query: 270 ASLDRHVKIY 279
S D +I+
Sbjct: 405 GSKDNTCRIW 414
Score = 53.6 bits (123), Expect = 2e-06
Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
CF G+L+ + ++F ++ + GH G + + F +++ S DK+
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTA 369
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+WD T + + HTD I A +I+++GS D+T +++
Sbjct: 370 RIWDAQTGQCLQVLEGHTDEI-FSCAFNYKGNIVITGSKDNTCRIW 414
>AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ40090 fis, clone TESTI2003596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 415
Score = 72.1 bits (169), Expect = 4e-12
Identities = 58/228 (25%), Positives = 99/228 (43%), Gaps = 6/228 (2%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQ-LKIISYSDDKSVGLWD 154
G + G + KL+D S L GH V+ F KI + S DK+ LW
Sbjct: 104 GSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWS 163
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ T + F HT I + +P S ++ +GS D T KL+D ++ E + T+ H + +
Sbjct: 164 VETGKCYHTFRGHTAEIVCLSFNPQS-TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEI 222
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL 272
S F SG I+ + VWD G K ++ + H +++ + S +++ S+
Sbjct: 223 ISLSFNTSGDRIITGSFDHTVVVWDADTGRK-VNILIGHCAEISSASFNWDCSLILTGSM 281
Query: 273 DRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
D+ K++D + K V + + IL ++ DG I
Sbjct: 282 DKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARI 329
Score = 68.5 bits (160), Expect = 5e-11
Identities = 45/198 (22%), Positives = 85/198 (42%), Gaps = 4/198 (2%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G + G + KL+ V++ F GHT + F + + S D + LWDI
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVE 214
E + H+ I + S D I++GS+DHTV ++D + + + + H + +
Sbjct: 207 QNGEEVYTLRGHSAEI-ISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 215 STLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLD 273
S F + ++ K+WD N GK ++ ++ H + + +AS D
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATN-GKCVATLTGHDDEILDSCFDYTGKLIATASAD 324
Query: 274 RHVKIYDVSTFKVVHNID 291
+I+ +T K + ++
Sbjct: 325 GTARIFSAATRKCIAKLE 342
Score = 68.1 bits (159), Expect = 7e-11
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 7/232 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F L+ G + KL+D+Q+ + GH+ + F +II+ S D +V
Sbjct: 185 FNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVV 244
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
+WD T ++ H I + A+ +IL+GS D T KL+D + + + T+ H
Sbjct: 245 VWDADTGRKVNILIGHCAEI-SSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHD 303
Query: 211 SPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + F +G + SA GT +++ K ++ + H ++ + + L+
Sbjct: 304 DEILDSCFDYTGKLIATASADGT-ARIFSAAT-RKCIAKLEGHEGEISKISFNPQGNHLL 361
Query: 269 SASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+ S D+ +I+D T + + ++ + I S A + +I+ G D I
Sbjct: 362 TGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRI 413
Score = 66.9 bits (156), Expect = 2e-10
Identities = 49/200 (24%), Positives = 90/200 (45%), Gaps = 4/200 (2%)
Query: 118 VLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAAS 177
+ +V H P+ K I+ S D++ LWD ++ E + H + + A A +
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAG-GTEIKV 235
D I +GS+D T KL+ + + T H + + F P + + T K+
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNA 295
WDI NG ++ + + H + +L ++ R+++ S D V ++D T + V+ + A
Sbjct: 204 WDIQNGEEVYT-LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCA 262
Query: 296 ILSMAISEHD-DILTVGMMD 314
+S A D ++ G MD
Sbjct: 263 EISSASFNWDCSLILTGSMD 282
Score = 54.0 bits (124), Expect = 1e-06
Identities = 37/190 (19%), Positives = 78/190 (41%), Gaps = 4/190 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G ++ G + V ++D + + + GH + F D I++ S DK+
Sbjct: 227 FNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCK 286
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
LWD + + +A H D I + + +I + S D T +++ + + I + H
Sbjct: 287 LWDATNGKCVATLTGHDDEI-LDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 211 SPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ F P G ++ + ++WD G+ L + H + + + +++
Sbjct: 346 GEISKISFNPQGNHLLTGSSDKTARIWDA-QTGQCLQVLEGHTDEIFSCAFNYKGNIVIT 404
Query: 270 ASLDRHVKIY 279
S D +I+
Sbjct: 405 GSKDNTCRIW 414
Score = 53.6 bits (123), Expect = 2e-06
Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
CF G+L+ + ++F ++ + GH G + + F +++ S DK+
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTA 369
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+WD T + + HTD I A +I+++GS D+T +++
Sbjct: 370 RIWDAQTGQCLQVLEGHTDEI-FSCAFNYKGNIVITGSKDNTCRIW 414
>AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein.
Length = 415
Score = 72.1 bits (169), Expect = 4e-12
Identities = 58/228 (25%), Positives = 99/228 (43%), Gaps = 6/228 (2%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQ-LKIISYSDDKSVGLWD 154
G + G + KL+D S L GH V+ F KI + S DK+ LW
Sbjct: 104 GSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWS 163
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ T + F HT I + +P S ++ +GS D T KL+D ++ E + T+ H + +
Sbjct: 164 VETGKCYHTFRGHTAEIVCLSFNPQS-TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEI 222
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL 272
S F SG I+ + VWD G K ++ + H +++ + S +++ S+
Sbjct: 223 ISLSFNTSGDRIITGSFDHTVVVWDADTGRK-VNILIGHCAEISSASFNWDCSLILTGSM 281
Query: 273 DRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
D+ K++D + K V + + IL ++ DG I
Sbjct: 282 DKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARI 329
Score = 68.5 bits (160), Expect = 5e-11
Identities = 45/198 (22%), Positives = 85/198 (42%), Gaps = 4/198 (2%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G + G + KL+ V++ F GHT + F + + S D + LWDI
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVE 214
E + H+ I + S D I++GS+DHTV ++D + + + + H + +
Sbjct: 207 QNGEEVYTLRGHSAEI-ISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 215 STLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLD 273
S F + ++ K+WD N GK ++ ++ H + + +AS D
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATN-GKCVATLTGHDDEILDSCFDYTGKLIATASAD 324
Query: 274 RHVKIYDVSTFKVVHNID 291
+I+ +T K + ++
Sbjct: 325 GTARIFSAATRKCIAKLE 342
Score = 68.1 bits (159), Expect = 7e-11
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 7/232 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F L+ G + KL+D+Q+ + GH+ + F +II+ S D +V
Sbjct: 185 FNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVV 244
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
+WD T ++ H I + A+ +IL+GS D T KL+D + + + T+ H
Sbjct: 245 VWDADTGRKVNILIGHCAEI-SSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHD 303
Query: 211 SPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + F +G + SA GT +++ K ++ + H ++ + + L+
Sbjct: 304 DEILDSCFDYTGKLIATASADGT-ARIFSAAT-RKCIAKLEGHEGEISKISFNPQGNHLL 361
Query: 269 SASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIISI 319
+ S D+ +I+D T + + ++ + I S A + +I+ G D I
Sbjct: 362 TGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRI 413
Score = 66.9 bits (156), Expect = 2e-10
Identities = 49/200 (24%), Positives = 90/200 (45%), Gaps = 4/200 (2%)
Query: 118 VLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAAS 177
+ +V H P+ K I+ S D++ LWD ++ E + H + + A A +
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAG-GTEIKV 235
D I +GS+D T KL+ + + T H + + F P + + T K+
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNA 295
WDI NG ++ + + H + +L ++ R+++ S D V ++D T + V+ + A
Sbjct: 204 WDIQNGEEVYT-LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCA 262
Query: 296 ILSMAISEHD-DILTVGMMD 314
+S A D ++ G MD
Sbjct: 263 EISSASFNWDCSLILTGSMD 282
Score = 54.0 bits (124), Expect = 1e-06
Identities = 37/190 (19%), Positives = 78/190 (41%), Gaps = 4/190 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G ++ G + V ++D + + + GH + F D I++ S DK+
Sbjct: 227 FNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCK 286
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
LWD + + +A H D I + + +I + S D T +++ + + I + H
Sbjct: 287 LWDATNGKCVATLTGHDDEI-LDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 211 SPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ F P G ++ + ++WD G+ L + H + + + +++
Sbjct: 346 GEISKISFNPQGNHLLTGSSDKTARIWDA-QTGQCLQVLEGHTDEIFSCAFNYKGNIVIT 404
Query: 270 ASLDRHVKIY 279
S D +I+
Sbjct: 405 GSKDNTCRIW 414
Score = 53.6 bits (123), Expect = 2e-06
Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
CF G+L+ + ++F ++ + GH G + + F +++ S DK+
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTA 369
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+WD T + + HTD I A +I+++GS D+T +++
Sbjct: 370 RIWDAQTGQCLQVLEGHTDEI-FSCAFNYKGNIVITGSKDNTCRIW 414
>AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ25955 fis, clone TST03904. ).
Length = 415
Score = 71.3 bits (167), Expect = 8e-12
Identities = 58/228 (25%), Positives = 99/228 (43%), Gaps = 6/228 (2%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQ-LKIISYSDDKSVGLWD 154
G + G + KL+D S L GH V+ F KI + S DK+ LW
Sbjct: 104 GSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWS 163
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ T + F HT I + +P S ++ +GS D T KL+D ++ E + T+ H + +
Sbjct: 164 VETGKCYHTFRGHTAEIVCLSFNPQS-TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEI 222
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL 272
S F SG I+ + VWD G K ++ + H +++ + S +++ S+
Sbjct: 223 ISLSFNTSGDRIITGSFDHTVVVWDADTGRK-VNILIGHCAEISSASFNWDCSLILTGSM 281
Query: 273 DRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI 319
D+ K++D + K V + + IL ++ DG I
Sbjct: 282 DKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARI 329
Score = 68.5 bits (160), Expect = 5e-11
Identities = 45/198 (22%), Positives = 85/198 (42%), Gaps = 4/198 (2%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G + G + KL+ V++ F GHT + F + + S D + LWDI
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVE 214
E + H+ I + S D I++GS+DHTV ++D + + + + H + +
Sbjct: 207 QNGEEVYTLRGHSAEI-ISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 215 STLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLD 273
S F + ++ K+WD N GK ++ ++ H + + +AS D
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATN-GKCVATLTGHDDEILDSCFDYTGKLIATASAD 324
Query: 274 RHVKIYDVSTFKVVHNID 291
+I+ +T K + ++
Sbjct: 325 GTARIFSAATRKCIAKLE 342
Score = 66.5 bits (155), Expect = 2e-10
Identities = 49/200 (24%), Positives = 90/200 (45%), Gaps = 4/200 (2%)
Query: 118 VLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAAS 177
+ +V H P+ K I+ S D++ LWD ++ E + H + + A A +
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFN 143
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAG-GTEIKV 235
D I +GS+D T KL+ + + T H + + F P + + T K+
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNA 295
WDI NG ++ + + H + +L ++ R+++ S D V ++D T + V+ + A
Sbjct: 204 WDIQNGEEVYT-LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCA 262
Query: 296 ILSMAISEHD-DILTVGMMD 314
+S A D ++ G MD
Sbjct: 263 EISSASFNWDCSLILTGSMD 282
Score = 66.1 bits (154), Expect = 3e-10
Identities = 51/224 (22%), Positives = 101/224 (45%), Gaps = 7/224 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F L+ G + KL+D+Q+ + GH+ + F +II+ S D +V
Sbjct: 185 FNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVV 244
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
+WD T ++ H I + A+ +IL+GS D T KL+D + + + T+ H
Sbjct: 245 VWDADTGRKVNILIGHCAEI-SSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHD 303
Query: 211 SPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + F +G + SA GT +++ K ++ + H ++ + + L+
Sbjct: 304 DEILDSCFDYTGKLIATASADGT-ARIFSAAT-RKCIAKLEGHEGEISKISFNPQGNHLL 361
Query: 269 SASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVG 311
+ S D+ +I+D T + + ++ + I S A + +I+ G
Sbjct: 362 TGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITG 405
Score = 50.8 bits (116), Expect = 1e-05
Identities = 24/106 (22%), Positives = 49/106 (46%), Gaps = 1/106 (0%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
CF G+L+ + ++F ++ + GH G + + F +++ S DK+
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTA 369
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+WD T + + HTD I A +I+++GS +T +++
Sbjct: 370 RIWDAQTGQCLQVLEGHTDEI-FSCAFNYKGNIVITGSKGNTCRIW 414
>AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens
cDNA FLJ45988 fis, clone PUAEN2006639, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 369
Score = 70.5 bits (165), Expect = 1e-11
Identities = 53/195 (27%), Positives = 90/195 (46%), Gaps = 5/195 (2%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQ-LKIISYSDDKSVGLWD 154
G + G + KL+D S L GH V+ F KI + S DK+ LW
Sbjct: 104 GSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWS 163
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPV 213
+ T + F HT I + +P S ++ +GS D T KL+D ++ E + T+ H + +
Sbjct: 164 VETGKCYHTFRGHTAEIVCLSFNPQS-TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEI 222
Query: 214 ESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL 272
S F SG I+ + VWD G K ++ + H +++ + S +++ S+
Sbjct: 223 ISLSFNTSGDRIITGSFDHTVVVWDADTGRK-VNILIGHCAEISSASFNWDCSLILTGSM 281
Query: 273 DRHVKIYDVSTFKVV 287
D+ K++D + K V
Sbjct: 282 DKTCKLWDATNGKCV 296
Score = 66.5 bits (155), Expect = 2e-10
Identities = 49/200 (24%), Positives = 90/200 (45%), Gaps = 4/200 (2%)
Query: 118 VLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAAS 177
+ +V H P+ K I+ S D++ LWD ++ E + H + + A A +
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFN 143
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAG-GTEIKV 235
D I +GS+D T KL+ + + T H + + F P + + T K+
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNA 295
WDI NG ++ + + H + +L ++ R+++ S D V ++D T + V+ + A
Sbjct: 204 WDIQNGEEVYT-LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCA 262
Query: 296 ILSMAISEHD-DILTVGMMD 314
+S A D ++ G MD
Sbjct: 263 EISSASFNWDCSLILTGSMD 282
Score = 62.5 bits (145), Expect = 4e-09
Identities = 43/185 (23%), Positives = 78/185 (42%), Gaps = 4/185 (2%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G + G + KL+ V++ F GHT + F + + S D + LWDI
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 156 STEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI-MTVNHGSPVE 214
E + H+ I + S D I++GS+DHTV ++D + + + + H + +
Sbjct: 207 QNGEEVYTLRGHSAEI-ISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 215 STLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLD 273
S F + ++ K+WD N GK ++ ++ H + + +AS D
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATN-GKCVATLTGHDDEILDSCFDYTGKLIATASAD 324
Query: 274 RHVKI 278
V +
Sbjct: 325 DGVSL 329
Score = 54.0 bits (124), Expect = 1e-06
Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 2/142 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F L+ G + KL+D+Q+ + GH+ + F +II+ S D +V
Sbjct: 185 FNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVV 244
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
+WD T ++ H I + A+ +IL+GS D T KL+D + + + T+ H
Sbjct: 245 VWDADTGRKVNILIGHCAEI-SSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHD 303
Query: 211 SPVESTLFLPSGGIFISAGGTE 232
+ + F +G + +A +
Sbjct: 304 DEILDSCFDYTGKLIATASADD 325
Score = 40.3 bits (90), Expect = 0.016
Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 3/108 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F G ++ G + V ++D + + + GH + F D I++ S DK+
Sbjct: 227 FNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCK 286
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
LWD + + +A H D I + + +I + S D V L CR
Sbjct: 287 LWDATNGKCVATLTGHDDEI-LDSCFDYTGKLIATASADDGVSL--CR 331
>BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide binding
protein (G protein), beta 5 protein.
Length = 353
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/227 (26%), Positives = 102/227 (44%), Gaps = 12/227 (5%)
Query: 62 CSVRVQVYDPVTKVVAKNISKFVEAAY-GGCF--RADGRLLVAGIEEAAVKLFDVQSKNV 118
CSV +D + AK S + Y C +D ++L A + L+DV+S +
Sbjct: 129 CSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTAS-GDGTCALWDVESGQL 187
Query: 119 LRVFTGHTGPVHRTFFTKDQL--KIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAA 176
L+ F GH V + +S DK +WD+ + + + F H I +
Sbjct: 188 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 247
Query: 177 SPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPV--ESTLFLPSGGIFISAGGTE-- 232
P S D SGS D T +LYD R++ + + S + S++ G + AG +
Sbjct: 248 YP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYT 306
Query: 233 IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
I VWD+ G + +S + H V+TLR++ + + S S D ++++
Sbjct: 307 INVWDVLKGSR-VSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 40.3 bits (90), Expect = 0.016
Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 12/178 (6%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH V + KD+ +I+S S D V +WD T + ++ A A +P
Sbjct: 57 RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP- 115
Query: 180 SPDIILSGSYDHTVKLYDCR--SNETI-----MTVNHGSPVESTLFLPSG-GIFISAGGT 231
S I G D+ +Y NE + H + + + F S I ++G
Sbjct: 116 SGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDG 175
Query: 232 EIKVWDIFNGGKLLSNISQHHKTVTTLRLA--SNNSRLMSASLDRHVKIYDVSTFKVV 287
+WD+ G+LL + H V L LA + +S D+ ++D+ + + V
Sbjct: 176 TCALWDV-ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCV 232
>AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide binding
protein beta 5 protein.
Length = 353
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/227 (26%), Positives = 102/227 (44%), Gaps = 12/227 (5%)
Query: 62 CSVRVQVYDPVTKVVAKNISKFVEAAY-GGCF--RADGRLLVAGIEEAAVKLFDVQSKNV 118
CSV +D + AK S + Y C +D ++L A + L+DV+S +
Sbjct: 129 CSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTAS-GDGTCALWDVESGQL 187
Query: 119 LRVFTGHTGPVHRTFFTKDQL--KIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAA 176
L+ F GH V + +S DK +WD+ + + + F H I +
Sbjct: 188 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 247
Query: 177 SPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPV--ESTLFLPSGGIFISAGGTE-- 232
P S D SGS D T +LYD R++ + + S + S++ G + AG +
Sbjct: 248 YP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYT 306
Query: 233 IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
I VWD+ G + +S + H V+TLR++ + + S S D ++++
Sbjct: 307 INVWDVLKGSR-VSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 40.3 bits (90), Expect = 0.016
Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 12/178 (6%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH V + KD+ +I+S S D V +WD T + ++ A A +P
Sbjct: 57 RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP- 115
Query: 180 SPDIILSGSYDHTVKLYDCR--SNETI-----MTVNHGSPVESTLFLPSG-GIFISAGGT 231
S I G D+ +Y NE + H + + + F S I ++G
Sbjct: 116 SGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDG 175
Query: 232 EIKVWDIFNGGKLLSNISQHHKTVTTLRLA--SNNSRLMSASLDRHVKIYDVSTFKVV 287
+WD+ G+LL + H V L LA + +S D+ ++D+ + + V
Sbjct: 176 TCALWDV-ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCV 232
>AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide binding
protein beta subunit 5L protein.
Length = 395
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/227 (26%), Positives = 102/227 (44%), Gaps = 12/227 (5%)
Query: 62 CSVRVQVYDPVTKVVAKNISKFVEAAY-GGCF--RADGRLLVAGIEEAAVKLFDVQSKNV 118
CSV +D + AK S + Y C +D ++L A + L+DV+S +
Sbjct: 171 CSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTAS-GDGTCALWDVESGQL 229
Query: 119 LRVFTGHTGPVHRTFFTKDQL--KIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAA 176
L+ F GH V + +S DK +WD+ + + + F H I +
Sbjct: 230 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 289
Query: 177 SPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPV--ESTLFLPSGGIFISAGGTE-- 232
P S D SGS D T +LYD R++ + + S + S++ G + AG +
Sbjct: 290 YP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYT 348
Query: 233 IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
I VWD+ G + +S + H V+TLR++ + + S S D ++++
Sbjct: 349 INVWDVLKGSR-VSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
Score = 40.3 bits (90), Expect = 0.016
Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 12/178 (6%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH V + KD+ +I+S S D V +WD T + ++ A A +P
Sbjct: 99 RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP- 157
Query: 180 SPDIILSGSYDHTVKLYDCR--SNETI-----MTVNHGSPVESTLFLPSG-GIFISAGGT 231
S I G D+ +Y NE + H + + + F S I ++G
Sbjct: 158 SGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDG 217
Query: 232 EIKVWDIFNGGKLLSNISQHHKTVTTLRLA--SNNSRLMSASLDRHVKIYDVSTFKVV 287
+WD+ G+LL + H V L LA + +S D+ ++D+ + + V
Sbjct: 218 TCALWDV-ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCV 274
>AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subunit
protein.
Length = 353
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/227 (26%), Positives = 102/227 (44%), Gaps = 12/227 (5%)
Query: 62 CSVRVQVYDPVTKVVAKNISKFVEAAY-GGCF--RADGRLLVAGIEEAAVKLFDVQSKNV 118
CSV +D + AK S + Y C +D ++L A + L+DV+S +
Sbjct: 129 CSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTAS-GDGTCALWDVESGQL 187
Query: 119 LRVFTGHTGPVHRTFFTKDQL--KIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAA 176
L+ F GH V + +S DK +WD+ + + + F H I +
Sbjct: 188 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 247
Query: 177 SPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPV--ESTLFLPSGGIFISAGGTE-- 232
P S D SGS D T +LYD R++ + + S + S++ G + AG +
Sbjct: 248 YP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYT 306
Query: 233 IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
I VWD+ G + +S + H V+TLR++ + + S S D ++++
Sbjct: 307 INVWDVLKGSR-VSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 40.3 bits (90), Expect = 0.016
Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 12/178 (6%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH V + KD+ +I+S S D V +WD T + ++ A A +P
Sbjct: 57 RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP- 115
Query: 180 SPDIILSGSYDHTVKLYDCR--SNETI-----MTVNHGSPVESTLFLPSG-GIFISAGGT 231
S I G D+ +Y NE + H + + + F S I ++G
Sbjct: 116 SGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDG 175
Query: 232 EIKVWDIFNGGKLLSNISQHHKTVTTLRLA--SNNSRLMSASLDRHVKIYDVSTFKVV 287
+WD+ G+LL + H V L LA + +S D+ ++D+ + + V
Sbjct: 176 TCALWDV-ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCV 232
>BC005870-1|AAH05870.1| 315|Homo sapiens mitogen-activated protein
kinase organizer 1 protein.
Length = 315
Score = 69.3 bits (162), Expect = 3e-11
Identities = 62/244 (25%), Positives = 110/244 (45%), Gaps = 10/244 (4%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
GA+ + F+ Y +++++P+ + + S D L +G
Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSG 85
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTE--ER 160
+ AV L+DV S V+R F GH G V+ F ++ I+S S D S+ WD + E
Sbjct: 86 GGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEP 145
Query: 161 IANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLP 220
+ +E D + ++ +S IL+GS D V+ YD R + + + GSP+ T F
Sbjct: 146 VQTLDEARDGV---SSVKVSDHEILAGSVDGRVRRYDLRMGQ-LFSDYVGSPITCTCFSR 201
Query: 221 SGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLR--LASNNSRLMSASLDRHVK 277
G +S+ + +++ D + G+LL H L L+ ++ ++S S D V
Sbjct: 202 DGQCTLVSSLDSTLRLLD-KDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVF 260
Query: 278 IYDV 281
+D+
Sbjct: 261 FWDL 264
Score = 34.3 bits (75), Expect = 1.1
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 7/128 (5%)
Query: 213 VESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSAS 271
V + F G ++ G + +K+W+ G LL S H V + +NS L S
Sbjct: 28 VRAVRFNVDGNYCLTCGSDKTLKLWNPLRG-TLLRTYSGHGYEVLDAAGSFDNSSLCSGG 86
Query: 272 LDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI----RKREEPV 326
D+ V ++DV++ +VV + ++ +E ++ G +D I +R EPV
Sbjct: 87 GDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPV 146
Query: 327 RQSEKRKN 334
+ ++ ++
Sbjct: 147 QTLDEARD 154
>AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein.
Length = 1336
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/217 (24%), Positives = 98/217 (45%), Gaps = 7/217 (3%)
Query: 73 TKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRT 132
TK V + +K + + +GR LV G L++ + N + H PV
Sbjct: 108 TKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAM 167
Query: 133 FFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHT 192
++ + + +++ V W S + F H + IR + SP + + + S D T
Sbjct: 168 TWSHNDMWMLTADHGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSP-TDNKFATCSDDGT 225
Query: 193 VKLYD-CRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNI 248
V+++D R +E + HG+ V+ + P+ G+ +S IK WD G+ L+ +
Sbjct: 226 VRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDP-KTGQSLATL 284
Query: 249 SQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFK 285
H TV ++L N + L++AS D K++D+ K
Sbjct: 285 HAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLK 321
Score = 44.4 bits (100), Expect = 0.001
Identities = 57/237 (24%), Positives = 97/237 (40%), Gaps = 13/237 (5%)
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI--STEERIANFN 165
VK + NV ++F H + F+ K + SDD +V +WD EERI
Sbjct: 185 VKYWQSNMNNV-KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERI--LR 241
Query: 166 EHTDYIRAGAASPISPDIILSGSYD--HTVKLYDCRSNETIMTVN-HGSPVESTLFLPSG 222
H ++ P + +++SGS D +K +D ++ +++ T++ H + V +G
Sbjct: 242 GHGADVKCVDWHP-TKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNG 300
Query: 223 GIFISAGGTEI-KVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM-SASLDRHVKIYD 280
++A + K++DI N + L H K T + + L S D + +
Sbjct: 301 NWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWH 360
Query: 281 VSTFKVVHNIDFPN--AILSMAISEHDDILTVGMMDGIISIRKREEPVRQSEKRKNL 335
V K V ++ + I S+A IL G D R P + R NL
Sbjct: 361 VGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNL 417
>AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein.
Length = 1336
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/217 (24%), Positives = 98/217 (45%), Gaps = 7/217 (3%)
Query: 73 TKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRT 132
TK V + +K + + +GR LV G L++ + N + H PV
Sbjct: 108 TKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAM 167
Query: 133 FFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHT 192
++ + + +++ V W S + F H + IR + SP + + + S D T
Sbjct: 168 TWSHNDMWMLTADHGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSP-TDNKFATCSDDGT 225
Query: 193 VKLYD-CRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNI 248
V+++D R +E + HG+ V+ + P+ G+ +S IK WD G+ L+ +
Sbjct: 226 VRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDP-KTGQSLATL 284
Query: 249 SQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFK 285
H TV ++L N + L++AS D K++D+ K
Sbjct: 285 HAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLK 321
Score = 44.4 bits (100), Expect = 0.001
Identities = 57/237 (24%), Positives = 97/237 (40%), Gaps = 13/237 (5%)
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI--STEERIANFN 165
VK + NV ++F H + F+ K + SDD +V +WD EERI
Sbjct: 185 VKYWQSNMNNV-KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERI--LR 241
Query: 166 EHTDYIRAGAASPISPDIILSGSYD--HTVKLYDCRSNETIMTVN-HGSPVESTLFLPSG 222
H ++ P + +++SGS D +K +D ++ +++ T++ H + V +G
Sbjct: 242 GHGADVKCVDWHP-TKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNG 300
Query: 223 GIFISAGGTEI-KVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM-SASLDRHVKIYD 280
++A + K++DI N + L H K T + + L S D + +
Sbjct: 301 NWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWH 360
Query: 281 VSTFKVVHNIDFPN--AILSMAISEHDDILTVGMMDGIISIRKREEPVRQSEKRKNL 335
V K V ++ + I S+A IL G D R P + R NL
Sbjct: 361 VGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNL 417
>BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS
box-containing 1 protein.
Length = 421
Score = 68.9 bits (161), Expect = 4e-11
Identities = 40/154 (25%), Positives = 80/154 (51%), Gaps = 4/154 (2%)
Query: 130 HRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSY 189
HR F +DQL + + ++ + +WD+ T + + N +HT+ +R +P I++S S
Sbjct: 132 HRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASR 191
Query: 190 DHTVKLYDCRSNETIMTV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLS 246
D T++++D + + +M V H + V S F P + S G ++ + +W++ + ++
Sbjct: 192 DKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNM-DKYTMIR 250
Query: 247 NISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+ HH V + + + L +AS D V I+D
Sbjct: 251 KLEGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/158 (24%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 65 RVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRL-LVAGIEEAAVKLFDVQSK-NVLRVF 122
R++++D T + N+ E F DG L LV+ + ++++D++ N+++V
Sbjct: 151 RIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVL 210
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
GH V+ F+ D + S K+V LW++ I H + A SPD
Sbjct: 211 RGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDV---VACDFSPD 267
Query: 183 --IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLF 218
++ + SYD V ++D + + +M H P + +F
Sbjct: 268 GALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIF 305
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 5/158 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKD-QLKIISYSDDKSV 150
F D LL G+ +K++DV + +L HT V F D L ++S S DK++
Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTL 195
Query: 151 GLWDISTEERIAN-FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+WD+ + + H +++ + A SP S ++ S V L++ I +
Sbjct: 196 RVWDLKDDGNMMKVLRGHQNWVYSCAFSPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEG 254
Query: 209 HGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLL 245
H V + F P G + +A T + +WD NG L+
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
>BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/235 (23%), Positives = 97/235 (41%), Gaps = 8/235 (3%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+D ++ G + V +FD S+ +L GHT V F Q + S S D ++ +W
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIW 291
Query: 154 DISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV---NHG 210
+ + H + G + + D +LS S D D ++ + V G
Sbjct: 292 SVPNASCVQVVRAHESAV-TGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSG 350
Query: 211 SPVESTLFLPSGGIF-ISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ F P G IF ++IK+WD+ ++N H +T++ + N L +
Sbjct: 351 CSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTN-VANFPGHSGPITSIAFSENGYYLAT 409
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPN--AILSMAISEHDDILTVGMMDGIISIRKR 322
A+ D VK++D+ K + N + S+ + L +G D I I K+
Sbjct: 410 AADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQ 464
Score = 65.7 bits (153), Expect = 4e-10
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 5/235 (2%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F P + F+A+ ++++ + + A G A G L++ ++
Sbjct: 272 FHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWA 331
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTF--FTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
D+Q+ VL T T T F D L + + D + +WD+ +ANF H
Sbjct: 332 FSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGH 391
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFI 226
+ I + A S + + + + D +VKL+D R + T+ + E +L G ++
Sbjct: 392 SGPITSIAFSE-NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYL 450
Query: 227 SAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+ GGT+++++ ++L + ++H T + + + S +DR +K Y +
Sbjct: 451 ALGGTDVQIYICKQWTEIL-HFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL 504
>BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/235 (23%), Positives = 97/235 (41%), Gaps = 8/235 (3%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+D ++ G + V +FD S+ +L GHT V F Q + S S D ++ +W
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIW 291
Query: 154 DISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV---NHG 210
+ + H + G + + D +LS S D D ++ + V G
Sbjct: 292 SVPNASCVQVVRAHESAV-TGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSG 350
Query: 211 SPVESTLFLPSGGIF-ISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ F P G IF ++IK+WD+ ++N H +T++ + N L +
Sbjct: 351 CSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTN-VANFPGHSGPITSIAFSENGYYLAT 409
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPN--AILSMAISEHDDILTVGMMDGIISIRKR 322
A+ D VK++D+ K + N + S+ + L +G D I I K+
Sbjct: 410 AADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQ 464
Score = 65.7 bits (153), Expect = 4e-10
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 5/235 (2%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F P + F+A+ ++++ + + A G A G L++ ++
Sbjct: 272 FHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWA 331
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTF--FTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
D+Q+ VL T T T F D L + + D + +WD+ +ANF H
Sbjct: 332 FSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGH 391
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFI 226
+ I + A S + + + + D +VKL+D R + T+ + E +L G ++
Sbjct: 392 SGPITSIAFSE-NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYL 450
Query: 227 SAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+ GGT+++++ ++L + ++H T + + + S +DR +K Y +
Sbjct: 451 ALGGTDVQIYICKQWTEIL-HFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL 504
>BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/235 (23%), Positives = 97/235 (41%), Gaps = 8/235 (3%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+D ++ G + V +FD S+ +L GHT V F Q + S S D ++ +W
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIW 291
Query: 154 DISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV---NHG 210
+ + H + G + + D +LS S D D ++ + V G
Sbjct: 292 SVPNASCVQVVRAHESAV-TGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSG 350
Query: 211 SPVESTLFLPSGGIF-ISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ F P G IF ++IK+WD+ ++N H +T++ + N L +
Sbjct: 351 CSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTN-VANFPGHSGPITSIAFSENGYYLAT 409
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPN--AILSMAISEHDDILTVGMMDGIISIRKR 322
A+ D VK++D+ K + N + S+ + L +G D I I K+
Sbjct: 410 AADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQ 464
Score = 65.7 bits (153), Expect = 4e-10
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 5/235 (2%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F P + F+A+ ++++ + + A G A G L++ ++
Sbjct: 272 FHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWA 331
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTF--FTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
D+Q+ VL T T T F D L + + D + +WD+ +ANF H
Sbjct: 332 FSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGH 391
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFI 226
+ I + A S + + + + D +VKL+D R + T+ + E +L G ++
Sbjct: 392 SGPITSIAFSE-NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYL 450
Query: 227 SAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+ GGT+++++ ++L + ++H T + + + S +DR +K Y +
Sbjct: 451 ALGGTDVQIYICKQWTEIL-HFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL 504
>AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens
cDNA FLJ90436 fis, clone NT2RP3000820, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA (EC
2.7.1.-). ).
Length = 421
Score = 68.9 bits (161), Expect = 4e-11
Identities = 40/154 (25%), Positives = 80/154 (51%), Gaps = 4/154 (2%)
Query: 130 HRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSY 189
HR F +DQL + + ++ + +WD+ T + + N +HT+ +R +P I++S S
Sbjct: 132 HRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASR 191
Query: 190 DHTVKLYDCRSNETIMTV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLS 246
D T++++D + + +M V H + V S F P + S G ++ + +W++ + ++
Sbjct: 192 DKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNM-DKYTMIR 250
Query: 247 NISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+ HH V + + + L +AS D V I+D
Sbjct: 251 KLEGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/158 (24%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 65 RVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRL-LVAGIEEAAVKLFDVQSK-NVLRVF 122
R++++D T + N+ E F DG L LV+ + ++++D++ N+++V
Sbjct: 151 RIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVL 210
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
GH V+ F+ D + S K+V LW++ I H + A SPD
Sbjct: 211 RGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDV---VACDFSPD 267
Query: 183 --IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLF 218
++ + SYD V ++D + + +M H P + +F
Sbjct: 268 GALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIF 305
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 5/158 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKD-QLKIISYSDDKSV 150
F D LL G+ +K++DV + +L HT V F D L ++S S DK++
Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTL 195
Query: 151 GLWDISTEERIAN-FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+WD+ + + H +++ + A SP S ++ S V L++ I +
Sbjct: 196 RVWDLKDDGNMMKVLRGHQNWVYSCAFSPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEG 254
Query: 209 HGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLL 245
H V + F P G + +A T + +WD NG L+
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
>AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein
NMP200 protein.
Length = 504
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/235 (23%), Positives = 97/235 (41%), Gaps = 8/235 (3%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+D ++ G + V +FD S+ +L GHT V F Q + S S D ++ +W
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIW 291
Query: 154 DISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV---NHG 210
+ + H + G + + D +LS S D D ++ + V G
Sbjct: 292 SVPNASCVQVVRAHESAV-TGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSG 350
Query: 211 SPVESTLFLPSGGIF-ISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ F P G IF ++IK+WD+ ++N H +T++ + N L +
Sbjct: 351 CSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTN-VANFPGHSGPITSIAFSENGYYLAT 409
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPN--AILSMAISEHDDILTVGMMDGIISIRKR 322
A+ D VK++D+ K + N + S+ + L +G D I I K+
Sbjct: 410 AADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQ 464
Score = 65.7 bits (153), Expect = 4e-10
Identities = 50/235 (21%), Positives = 102/235 (43%), Gaps = 5/235 (2%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
F P + F+A+ ++++ + + A G A G L++ ++
Sbjct: 272 FHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWA 331
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTF--FTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
D+Q+ VL T T T F D L + + D + +WD+ +ANF H
Sbjct: 332 FSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGH 391
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFI 226
+ I + A S + + + + D +VKL+D R + T+ + E +L G ++
Sbjct: 392 SGPITSIAFSE-NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYL 450
Query: 227 SAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+ GGT+++++ ++L + ++H T + + + S +DR +K Y +
Sbjct: 451 ALGGTDVQIYICKQWTEIL-HFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL 504
>AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein.
Length = 421
Score = 68.9 bits (161), Expect = 4e-11
Identities = 40/154 (25%), Positives = 80/154 (51%), Gaps = 4/154 (2%)
Query: 130 HRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSY 189
HR F +DQL + + ++ + +WD+ T + + N +HT+ +R +P I++S S
Sbjct: 132 HRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASR 191
Query: 190 DHTVKLYDCRSNETIMTV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLS 246
D T++++D + + +M V H + V S F P + S G ++ + +W++ + ++
Sbjct: 192 DKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNM-DKYTMIR 250
Query: 247 NISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+ HH V + + + L +AS D V I+D
Sbjct: 251 KLEGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/158 (24%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 65 RVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRL-LVAGIEEAAVKLFDVQSK-NVLRVF 122
R++++D T + N+ E F DG L LV+ + ++++D++ N+++V
Sbjct: 151 RIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVL 210
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
GH V+ F+ D + S K+V LW++ I H + A SPD
Sbjct: 211 RGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDV---VACDFSPD 267
Query: 183 --IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLF 218
++ + SYD V ++D + + +M H P + +F
Sbjct: 268 GALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIF 305
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 5/158 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKD-QLKIISYSDDKSV 150
F D LL G+ +K++DV + +L HT V F D L ++S S DK++
Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTL 195
Query: 151 GLWDISTEERIAN-FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+WD+ + + H +++ + A SP S ++ S V L++ I +
Sbjct: 196 RVWDLKDDGNMMKVLRGHQNWVYSCAFSPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEG 254
Query: 209 HGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLL 245
H V + F P G + +A T + +WD NG L+
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
>AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD
protein SWiP-1 protein.
Length = 421
Score = 68.9 bits (161), Expect = 4e-11
Identities = 40/154 (25%), Positives = 80/154 (51%), Gaps = 4/154 (2%)
Query: 130 HRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSY 189
HR F +DQL + + ++ + +WD+ T + + N +HT+ +R +P I++S S
Sbjct: 132 HRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASR 191
Query: 190 DHTVKLYDCRSNETIMTV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLS 246
D T++++D + + +M V H + V S F P + S G ++ + +W++ + ++
Sbjct: 192 DKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNM-DKYTMIR 250
Query: 247 NISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+ HH V + + + L +AS D V I+D
Sbjct: 251 KLEGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/158 (24%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 65 RVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRL-LVAGIEEAAVKLFDVQSK-NVLRVF 122
R++++D T + N+ E F DG L LV+ + ++++D++ N+++V
Sbjct: 151 RIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVL 210
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
GH V+ F+ D + S K+V LW++ I H + A SPD
Sbjct: 211 RGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDV---VACDFSPD 267
Query: 183 --IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLF 218
++ + SYD V ++D + + +M H P + +F
Sbjct: 268 GALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIF 305
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 5/158 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKD-QLKIISYSDDKSV 150
F D LL G+ +K++DV + +L HT V F D L ++S S DK++
Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTL 195
Query: 151 GLWDISTEERIAN-FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+WD+ + + H +++ + A SP S ++ S V L++ I +
Sbjct: 196 RVWDLKDDGNMMKVLRGHQNWVYSCAFSPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEG 254
Query: 209 HGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLL 245
H V + F P G + +A T + +WD NG L+
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
>AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein.
Length = 421
Score = 68.9 bits (161), Expect = 4e-11
Identities = 40/154 (25%), Positives = 80/154 (51%), Gaps = 4/154 (2%)
Query: 130 HRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSY 189
HR F +DQL + + ++ + +WD+ T + + N +HT+ +R +P I++S S
Sbjct: 132 HRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASR 191
Query: 190 DHTVKLYDCRSNETIMTV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLS 246
D T++++D + + +M V H + V S F P + S G ++ + +W++ + ++
Sbjct: 192 DKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNM-DKYTMIR 250
Query: 247 NISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+ HH V + + + L +AS D V I+D
Sbjct: 251 KLEGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/158 (24%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 65 RVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRL-LVAGIEEAAVKLFDVQSK-NVLRVF 122
R++++D T + N+ E F DG L LV+ + ++++D++ N+++V
Sbjct: 151 RIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVL 210
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
GH V+ F+ D + S K+V LW++ I H + A SPD
Sbjct: 211 RGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDV---VACDFSPD 267
Query: 183 --IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLF 218
++ + SYD V ++D + + +M H P + +F
Sbjct: 268 GALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIF 305
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 5/158 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKD-QLKIISYSDDKSV 150
F D LL G+ +K++DV + +L HT V F D L ++S S DK++
Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTL 195
Query: 151 GLWDISTEERIAN-FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+WD+ + + H +++ + A SP S ++ S V L++ I +
Sbjct: 196 RVWDLKDDGNMMKVLRGHQNWVYSCAFSPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEG 254
Query: 209 HGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLL 245
H V + F P G + +A T + +WD NG L+
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
>BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61
protein.
Length = 305
Score = 68.5 bits (160), Expect = 5e-11
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 1/149 (0%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
+SP Y + + ++D T + + F D +LLV ++ +K
Sbjct: 156 YSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIK 215
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
++DVQ N+ +GH V F D +S S DKSV +WD+ T + F +H D
Sbjct: 216 IYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQD 275
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDC 198
+ + I+ G D + +YDC
Sbjct: 276 QVWGVKYNGNGSKIVSVGD-DQEIHIYDC 303
Score = 58.8 bits (136), Expect = 4e-08
Identities = 38/186 (20%), Positives = 88/186 (47%), Gaps = 4/186 (2%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+A ++L+D+++ ++ F+ D + + + V ++ + + ++ +
Sbjct: 85 DAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSL 144
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGG 223
+ +I + A SP + SG+ D + ++D + + + T+ H P+ S F P
Sbjct: 145 DTRGKFILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQ 203
Query: 224 IFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVS 282
+ ++A IK++D+ + L +S H V + +++ +S+S D+ VK++DV
Sbjct: 204 LLVTASDDGYIKIYDVQHAN-LAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVG 262
Query: 283 TFKVVH 288
T VH
Sbjct: 263 TRTCVH 268
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/140 (25%), Positives = 66/140 (47%), Gaps = 4/140 (2%)
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFN-- 240
I S S D ++L+D + + I +++ G PV++ S A GT + +IF
Sbjct: 78 IAASSSLDAHIRLWDLENGKQIKSIDAG-PVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID-FPNAILSM 299
GK ++ K + ++ + + L S ++D + I+D++T K++H ++ I S+
Sbjct: 137 SGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSL 196
Query: 300 AISEHDDILTVGMMDGIISI 319
S +L DG I I
Sbjct: 197 TFSPDSQLLVTASDDGYIKI 216
Score = 47.2 bits (107), Expect = 1e-04
Identities = 37/142 (26%), Positives = 72/142 (50%), Gaps = 6/142 (4%)
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S S D + LWD+ ++I + + A SP S + +G++ V ++ S +
Sbjct: 81 SSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS-QYLATGTHVGKVNIFGVESGK 139
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLR 259
+++ G + S + P G ++++G + I ++DI G KLL + H + +L
Sbjct: 140 KEYSLDTRGKFILSIAYSPDGK-YLASGAIDGIINIFDIATG-KLLHTLEGHAMPIRSLT 197
Query: 260 LASNNSRLMSASLDRHVKIYDV 281
+ ++ L++AS D ++KIYDV
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDV 219
Score = 40.7 bits (91), Expect = 0.012
Identities = 25/107 (23%), Positives = 46/107 (42%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L FSP A+ +++YD +A +S F D V+ + +
Sbjct: 196 LTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKS 255
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
VK++DV ++ + F H V + + KI+S DD+ + ++D
Sbjct: 256 VKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
>AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21101 fis, clone CAS04682. ).
Length = 305
Score = 68.5 bits (160), Expect = 5e-11
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 1/149 (0%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
+SP Y + + ++D T + + F D +LLV ++ +K
Sbjct: 156 YSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIK 215
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
++DVQ N+ +GH V F D +S S DKSV +WD+ T + F +H D
Sbjct: 216 IYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQD 275
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDC 198
+ + I+ G D + +YDC
Sbjct: 276 QVWGVKYNGNGSKIVSVGD-DQEIHIYDC 303
Score = 58.8 bits (136), Expect = 4e-08
Identities = 38/186 (20%), Positives = 88/186 (47%), Gaps = 4/186 (2%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+A ++L+D+++ ++ F+ D + + + V ++ + + ++ +
Sbjct: 85 DAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSL 144
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGG 223
+ +I + A SP + SG+ D + ++D + + + T+ H P+ S F P
Sbjct: 145 DTRGKFILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQ 203
Query: 224 IFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVS 282
+ ++A IK++D+ + L +S H V + +++ +S+S D+ VK++DV
Sbjct: 204 LLVTASDDGYIKIYDVQHAN-LAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVG 262
Query: 283 TFKVVH 288
T VH
Sbjct: 263 TRTCVH 268
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/140 (25%), Positives = 66/140 (47%), Gaps = 4/140 (2%)
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFN-- 240
I S S D ++L+D + + I +++ G PV++ S A GT + +IF
Sbjct: 78 IAASSSLDAHIRLWDLENGKQIKSIDAG-PVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID-FPNAILSM 299
GK ++ K + ++ + + L S ++D + I+D++T K++H ++ I S+
Sbjct: 137 SGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSL 196
Query: 300 AISEHDDILTVGMMDGIISI 319
S +L DG I I
Sbjct: 197 TFSPDSQLLVTASDDGYIKI 216
Score = 47.2 bits (107), Expect = 1e-04
Identities = 37/142 (26%), Positives = 72/142 (50%), Gaps = 6/142 (4%)
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S S D + LWD+ ++I + + A SP S + +G++ V ++ S +
Sbjct: 81 SSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS-QYLATGTHVGKVNIFGVESGK 139
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLR 259
+++ G + S + P G ++++G + I ++DI G KLL + H + +L
Sbjct: 140 KEYSLDTRGKFILSIAYSPDGK-YLASGAIDGIINIFDIATG-KLLHTLEGHAMPIRSLT 197
Query: 260 LASNNSRLMSASLDRHVKIYDV 281
+ ++ L++AS D ++KIYDV
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDV 219
Score = 40.7 bits (91), Expect = 0.012
Identities = 25/107 (23%), Positives = 46/107 (42%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L FSP A+ +++YD +A +S F D V+ + +
Sbjct: 196 LTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKS 255
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
VK++DV ++ + F H V + + KI+S DD+ + ++D
Sbjct: 256 VKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
>AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination
protein REC14 protein.
Length = 305
Score = 68.5 bits (160), Expect = 5e-11
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 1/149 (0%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
+SP Y + + ++D T + + F D +LLV ++ +K
Sbjct: 156 YSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIK 215
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
++DVQ N+ +GH V F D +S S DKSV +WD+ T + F +H D
Sbjct: 216 IYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQD 275
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDC 198
+ + I+ G D + +YDC
Sbjct: 276 QVWGVKYNGNGSKIVSVGD-DQEIHIYDC 303
Score = 58.8 bits (136), Expect = 4e-08
Identities = 38/186 (20%), Positives = 88/186 (47%), Gaps = 4/186 (2%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+A ++L+D+++ ++ F+ D + + + V ++ + + ++ +
Sbjct: 85 DAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSL 144
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGG 223
+ +I + A SP + SG+ D + ++D + + + T+ H P+ S F P
Sbjct: 145 DTRGKFILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQ 203
Query: 224 IFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVS 282
+ ++A IK++D+ + L +S H V + +++ +S+S D+ VK++DV
Sbjct: 204 LLVTASDDGYIKIYDVQHAN-LAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVG 262
Query: 283 TFKVVH 288
T VH
Sbjct: 263 TRTCVH 268
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/140 (25%), Positives = 66/140 (47%), Gaps = 4/140 (2%)
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFN-- 240
I S S D ++L+D + + I +++ G PV++ S A GT + +IF
Sbjct: 78 IAASSSLDAHIRLWDLENGKQIKSIDAG-PVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID-FPNAILSM 299
GK ++ K + ++ + + L S ++D + I+D++T K++H ++ I S+
Sbjct: 137 SGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSL 196
Query: 300 AISEHDDILTVGMMDGIISI 319
S +L DG I I
Sbjct: 197 TFSPDSQLLVTASDDGYIKI 216
Score = 47.2 bits (107), Expect = 1e-04
Identities = 37/142 (26%), Positives = 72/142 (50%), Gaps = 6/142 (4%)
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S S D + LWD+ ++I + + A SP S + +G++ V ++ S +
Sbjct: 81 SSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS-QYLATGTHVGKVNIFGVESGK 139
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLR 259
+++ G + S + P G ++++G + I ++DI G KLL + H + +L
Sbjct: 140 KEYSLDTRGKFILSIAYSPDGK-YLASGAIDGIINIFDIATG-KLLHTLEGHAMPIRSLT 197
Query: 260 LASNNSRLMSASLDRHVKIYDV 281
+ ++ L++AS D ++KIYDV
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDV 219
Score = 40.7 bits (91), Expect = 0.012
Identities = 25/107 (23%), Positives = 46/107 (42%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L FSP A+ +++YD +A +S F D V+ + +
Sbjct: 196 LTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKS 255
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
VK++DV ++ + F H V + + KI+S DD+ + ++D
Sbjct: 256 VKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
>AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta
subunit-like protein protein.
Length = 305
Score = 68.5 bits (160), Expect = 5e-11
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 1/149 (0%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
+SP Y + + ++D T + + F D +LLV ++ +K
Sbjct: 156 YSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIK 215
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
++DVQ N+ +GH V F D +S S DKSV +WD+ T + F +H D
Sbjct: 216 IYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQD 275
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDC 198
+ + I+ G D + +YDC
Sbjct: 276 QVWGVKYNGNGSKIVSVGD-DQEIHIYDC 303
Score = 58.8 bits (136), Expect = 4e-08
Identities = 38/186 (20%), Positives = 88/186 (47%), Gaps = 4/186 (2%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+A ++L+D+++ ++ F+ D + + + V ++ + + ++ +
Sbjct: 85 DAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSL 144
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGG 223
+ +I + A SP + SG+ D + ++D + + + T+ H P+ S F P
Sbjct: 145 DTRGKFILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQ 203
Query: 224 IFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVS 282
+ ++A IK++D+ + L +S H V + +++ +S+S D+ VK++DV
Sbjct: 204 LLVTASDDGYIKIYDVQHAN-LAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVG 262
Query: 283 TFKVVH 288
T VH
Sbjct: 263 TRTCVH 268
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/140 (25%), Positives = 66/140 (47%), Gaps = 4/140 (2%)
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFN-- 240
I S S D ++L+D + + I +++ G PV++ S A GT + +IF
Sbjct: 78 IAASSSLDAHIRLWDLENGKQIKSIDAG-PVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID-FPNAILSM 299
GK ++ K + ++ + + L S ++D + I+D++T K++H ++ I S+
Sbjct: 137 SGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSL 196
Query: 300 AISEHDDILTVGMMDGIISI 319
S +L DG I I
Sbjct: 197 TFSPDSQLLVTASDDGYIKI 216
Score = 47.2 bits (107), Expect = 1e-04
Identities = 37/142 (26%), Positives = 72/142 (50%), Gaps = 6/142 (4%)
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S S D + LWD+ ++I + + A SP S + +G++ V ++ S +
Sbjct: 81 SSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS-QYLATGTHVGKVNIFGVESGK 139
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLR 259
+++ G + S + P G ++++G + I ++DI G KLL + H + +L
Sbjct: 140 KEYSLDTRGKFILSIAYSPDGK-YLASGAIDGIINIFDIATG-KLLHTLEGHAMPIRSLT 197
Query: 260 LASNNSRLMSASLDRHVKIYDV 281
+ ++ L++AS D ++KIYDV
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDV 219
Score = 40.7 bits (91), Expect = 0.012
Identities = 25/107 (23%), Positives = 46/107 (42%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L FSP A+ +++YD +A +S F D V+ + +
Sbjct: 196 LTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKS 255
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
VK++DV ++ + F H V + + KI+S DD+ + ++D
Sbjct: 256 VKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
>AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein.
Length = 348
Score = 68.1 bits (159), Expect = 7e-11
Identities = 39/147 (26%), Positives = 72/147 (48%), Gaps = 3/147 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F DGRL+V+ E+ +K++D +K + F+ G + F I S D++V
Sbjct: 22 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 81
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
+WD+ + + ++ H+ + + P S + +++ S D T+K+ D I T+ H
Sbjct: 82 VWDVRVNKLLQHYQVHSGGVNCISFHP-SGNYLITASSDGTLKILDLLEGRLIYTLQGHT 140
Query: 211 SPVESTLFLPSGGIFISAGG-TEIKVW 236
PV + F G +F S G T++ +W
Sbjct: 141 GPVFTVSFSKGGELFASGGADTQVLLW 167
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/157 (27%), Positives = 73/157 (46%), Gaps = 4/157 (2%)
Query: 125 HTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDII 184
HT V F+ D I+S S+DK++ +WD + ++ + NF++ + +P I
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 72
Query: 185 LSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGG 242
+GS D TVK++D R N+ + H V F PSG I+A +K+ D+ G
Sbjct: 73 SAGS-DQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLE-G 130
Query: 243 KLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
+L+ + H V T+ + S D V ++
Sbjct: 131 RLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 167
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/117 (23%), Positives = 47/117 (40%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G +++DF+P +A V+V+D + ++ F G L+
Sbjct: 57 GFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITA 116
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEE 159
+ +K+ D+ ++ GHTGPV F+K S D V LW + +E
Sbjct: 117 SSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDE 173
Score = 39.9 bits (89), Expect = 0.022
Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
FSP + + ++++D K N S V A F G + + + VK
Sbjct: 22 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 81
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
++DV+ +L+ + H+G V+ F +I+ S D ++ + D+ I HT
Sbjct: 82 VWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTG 141
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
+ + S ++ SG D V L+ +E
Sbjct: 142 PVFTVSFSK-GGELFASGGADTQVLLWRTNFDE 173
>AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein.
Length = 348
Score = 68.1 bits (159), Expect = 7e-11
Identities = 39/147 (26%), Positives = 72/147 (48%), Gaps = 3/147 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F DGRL+V+ E+ +K++D +K + F+ G + F I S D++V
Sbjct: 22 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 81
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHG 210
+WD+ + + ++ H+ + + P S + +++ S D T+K+ D I T+ H
Sbjct: 82 VWDVRVNKLLQHYQVHSGGVNCISFHP-SGNYLITASSDGTLKILDLLEGRLIYTLQGHT 140
Query: 211 SPVESTLFLPSGGIFISAGG-TEIKVW 236
PV + F G +F S G T++ +W
Sbjct: 141 GPVFTVSFSKGGELFASGGADTQVLLW 167
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/157 (27%), Positives = 73/157 (46%), Gaps = 4/157 (2%)
Query: 125 HTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDII 184
HT V F+ D I+S S+DK++ +WD + ++ + NF++ + +P I
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 72
Query: 185 LSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGG 242
+GS D TVK++D R N+ + H V F PSG I+A +K+ D+ G
Sbjct: 73 SAGS-DQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLE-G 130
Query: 243 KLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
+L+ + H V T+ + S D V ++
Sbjct: 131 RLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 167
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/117 (23%), Positives = 47/117 (40%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G +++DF+P +A V+V+D + ++ F G L+
Sbjct: 57 GFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITA 116
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEE 159
+ +K+ D+ ++ GHTGPV F+K S D V LW + +E
Sbjct: 117 SSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDE 173
Score = 39.9 bits (89), Expect = 0.022
Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
FSP + + ++++D K N S V A F G + + + VK
Sbjct: 22 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 81
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
++DV+ +L+ + H+G V+ F +I+ S D ++ + D+ I HT
Sbjct: 82 VWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTG 141
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
+ + S ++ SG D V L+ +E
Sbjct: 142 PVFTVSFSK-GGELFASGGADTQVLLWRTNFDE 173
>X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRNA
for beta-subunit signal transducing proteins Gs/Gi
(beta-G). ).
Length = 340
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 145 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G+ + + H V +L LA + +S + D K++DV
Sbjct: 168 LWDI-ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
>M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transducin
beta-1 subunit mRNA, 3' end. ).
Length = 247
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 52 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 111
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 112 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 170
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 171 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 229
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 230 DGMAVATGSWDSFLKIWN 247
>CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein.
Length = 340
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 145 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G+ + + H V +L LA + +S + D K++DV
Sbjct: 168 LWDI-ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
>BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 145 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G+ + + H V +L LA + +S + D K++DV
Sbjct: 168 LWDI-ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
>BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 145 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G+ + + H V +L LA + +S + D K++DV
Sbjct: 168 LWDI-ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
>BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 145 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G+ + + H V +L LA + +S + D K++DV
Sbjct: 168 LWDI-ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
>BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 145 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G+ + + H V +L LA + +S + D K++DV
Sbjct: 168 LWDI-ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
>AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 145 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G+ + + H V +L LA + +S + D K++DV
Sbjct: 168 LWDI-ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
>AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide
binding protein (G protein), beta polypeptide 1 protein.
Length = 197
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 2 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 61
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 62 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 120
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 121 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 179
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 180 DGMAVATGSWDSFLKIWN 197
>AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 145 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G+ + + H V +L LA + +S + D K++DV
Sbjct: 168 LWDI-ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
>AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide binding
protein beta 1 protein.
Length = 340
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 145 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G+ + + H V +L LA + +S + D K++DV
Sbjct: 168 LWDI-ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
>AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal
transducing proteins GS/GI protein.
Length = 207
Score = 67.7 bits (158), Expect = 9e-11
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 12 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 71
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 72 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 130
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 131 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 189
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 190 DGMAVATGSWDSFLKIWN 207
>AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein.
Length = 421
Score = 67.3 bits (157), Expect = 1e-10
Identities = 39/154 (25%), Positives = 79/154 (51%), Gaps = 4/154 (2%)
Query: 130 HRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSY 189
HR F +DQL + + ++ + +WD+ T + + N +HT+ +R +P I++S S
Sbjct: 132 HRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTLAPDGSLILVSASR 191
Query: 190 DHTVKLYDCRSNETIMTV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLS 246
D T++++D + + +M V H + V S F P + G ++ + +W++ + ++
Sbjct: 192 DKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCPVGASKAVFLWNM-DKYTMIR 250
Query: 247 NISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+ HH V + + + L +AS D V I+D
Sbjct: 251 KLEGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 53.6 bits (123), Expect = 2e-06
Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 7/158 (4%)
Query: 65 RVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRL-LVAGIEEAAVKLFDVQSK-NVLRVF 122
R++++D T + N+ E DG L LV+ + ++++D++ N+++V
Sbjct: 151 RIKIWDVYTGKLLLNLVDHTEVVRDLTLAPDGSLILVSASRDKTLRVWDLKDDGNMMKVL 210
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
GH V+ F+ D + K+V LW++ I H + A SPD
Sbjct: 211 RGHQNWVYSCAFSPDSSMLCPVGASKAVFLWNMDKYTMIRKLEGHHHDV---VACDFSPD 267
Query: 183 --IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLF 218
++ + SYD V ++D + + +M H P + +F
Sbjct: 268 GALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIF 305
Score = 52.0 bits (119), Expect = 5e-06
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 5/158 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKD-QLKIISYSDDKSV 150
F D LL G+ +K++DV + +L HT V D L ++S S DK++
Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTLAPDGSLILVSASRDKTL 195
Query: 151 GLWDISTEERIAN-FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+WD+ + + H +++ + A SP S + G+ V L++ I +
Sbjct: 196 RVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCPVGA-SKAVFLWNMDKYTMIRKLEG 254
Query: 209 HGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLL 245
H V + F P G + +A T + +WD NG L+
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
>BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat domain
containing 11 protein.
Length = 529
Score = 66.9 bits (156), Expect = 2e-10
Identities = 45/191 (23%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R++V G ++ V+++DV + VL H V F+ + ++ S D+S+
Sbjct: 272 CLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLM--VTCSKDRSI 329
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K++ + E + T+N
Sbjct: 330 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGH 389
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 390 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 446
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 447 AYDGKIKVWDL 457
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/195 (24%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D +++G+ + ++K++D S L+V TGHTG V D+ I++ S D +V
Sbjct: 232 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCLQYDERVIVTGSSDSTV 289
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A S ++++ S D ++ ++D S I +
Sbjct: 290 RVWDVNTGEVLNTLIHHNE---AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVL 346
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW + + + ++ H + + L+ +
Sbjct: 347 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWST-STCEFVRTLNGHKRGIACLQY--RDRL 402
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 403 VVSGSSDNTIRLWDI 417
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/184 (23%), Positives = 85/184 (46%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KIIS D S+ +WD ++ E + HT + +I++GS D TV+++
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV---LCLQYDERVIVTGSSDSTVRVW 292
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H + L +G + + I VWD+ + + L + H+
Sbjct: 293 DVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAA 352
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K++ ST + V ++ ++ + D ++ G D
Sbjct: 353 VNV-VDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 410
Query: 316 IISI 319
I +
Sbjct: 411 TIRL 414
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V+ T + ++ C +
Sbjct: 345 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGI--ACLQYRD 400
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 401 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 457
Score = 39.5 bits (88), Expect = 0.029
Identities = 24/106 (22%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
D + +V+ + +K++ + +R GH + + +D+L ++S S D ++ LWD
Sbjct: 359 DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY-RDRL-VVSGSSDNTIRLWD 416
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRS 200
I + H + +R I+SG+YD +K++D ++
Sbjct: 417 IECGACLRVLEGHEELVRC---IRFDNKRIVSGAYDGKIKVWDLQA 459
Score = 38.7 bits (86), Expect = 0.050
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQ---------SKNVLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+Q S LR H+G V R F D+ +I
Sbjct: 435 CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQF--DEFQI 492
Query: 142 ISYSDDKSVGLWD 154
IS S D ++ +WD
Sbjct: 493 ISSSHDDTILIWD 505
>AK223195-1|BAD96915.1| 315|Homo sapiens mitogen-activated protein
kinase organizer 1 variant protein.
Length = 315
Score = 66.9 bits (156), Expect = 2e-10
Identities = 61/244 (25%), Positives = 109/244 (44%), Gaps = 10/244 (4%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
GA+ + F+ Y +++++P+ + + S D L +G
Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSG 85
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTE--ER 160
+ AV L+DV S V+R F GH G V+ F ++ I+S S D S+ WD + E
Sbjct: 86 GGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEP 145
Query: 161 IANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLP 220
+ +E D + ++ + IL+GS D V+ YD R + + + GSP+ T F
Sbjct: 146 VQTLDEARDGV---SSVKVLDHEILAGSVDGRVRRYDLRMGQ-LFSDYVGSPITCTCFSR 201
Query: 221 SGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLR--LASNNSRLMSASLDRHVK 277
G +S+ + +++ D + G+LL H L L+ ++ ++S S D V
Sbjct: 202 DGQCTLVSSLDSTLRLLD-KDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVF 260
Query: 278 IYDV 281
+D+
Sbjct: 261 FWDL 264
Score = 34.3 bits (75), Expect = 1.1
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 7/128 (5%)
Query: 213 VESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSAS 271
V + F G ++ G + +K+W+ G LL S H V + +NS L S
Sbjct: 28 VRAVRFNVDGNYCLTCGSDKTLKLWNPLRG-TLLRTYSGHGYEVLDAAGSFDNSSLCSGG 86
Query: 272 LDRHVKIYDVSTFKVVHNI-DFPNAILSMAISEHDDILTVGMMDGIISI----RKREEPV 326
D+ V ++DV++ +VV + ++ +E ++ G +D I +R EPV
Sbjct: 87 GDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPV 146
Query: 327 RQSEKRKN 334
+ ++ ++
Sbjct: 147 QTLDEARD 154
>AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b
protein.
Length = 542
Score = 66.9 bits (156), Expect = 2e-10
Identities = 45/191 (23%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R++V G ++ V+++DV + VL H V F+ + ++ S D+S+
Sbjct: 285 CLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLM--VTCSKDRSI 342
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K++ + E + T+N
Sbjct: 343 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGH 402
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 403 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 459
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 460 AYDGKIKVWDL 470
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/195 (24%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D +++G+ + ++K++D S L+V TGHTG V D+ I++ S D +V
Sbjct: 245 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCLQYDERVIVTGSSDSTV 302
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A S ++++ S D ++ ++D S I +
Sbjct: 303 RVWDVNTGEVLNTLIHHNE---AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVL 359
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW + + + ++ H + + L+ +
Sbjct: 360 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWST-STCEFVRTLNGHKRGIACLQY--RDRL 415
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 416 VVSGSSDNTIRLWDI 430
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/184 (23%), Positives = 85/184 (46%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KIIS D S+ +WD ++ E + HT + +I++GS D TV+++
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV---LCLQYDERVIVTGSSDSTVRVW 305
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H + L +G + + I VWD+ + + L + H+
Sbjct: 306 DVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAA 365
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K++ ST + V ++ ++ + D ++ G D
Sbjct: 366 VNV-VDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 423
Query: 316 IISI 319
I +
Sbjct: 424 TIRL 427
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V+ T + ++ C +
Sbjct: 358 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGI--ACLQYRD 413
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 414 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 470
Score = 39.5 bits (88), Expect = 0.029
Identities = 24/106 (22%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
D + +V+ + +K++ + +R GH + + +D+L ++S S D ++ LWD
Sbjct: 372 DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY-RDRL-VVSGSSDNTIRLWD 429
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRS 200
I + H + +R I+SG+YD +K++D ++
Sbjct: 430 IECGACLRVLEGHEELVRC---IRFDNKRIVSGAYDGKIKVWDLQA 472
Score = 38.7 bits (86), Expect = 0.050
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQ---------SKNVLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+Q S LR H+G V R F D+ +I
Sbjct: 448 CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQF--DEFQI 505
Query: 142 ISYSDDKSVGLWD 154
IS S D ++ +WD
Sbjct: 506 ISSSHDDTILIWD 518
>AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform C protein.
Length = 542
Score = 66.9 bits (156), Expect = 2e-10
Identities = 45/191 (23%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R++V G ++ V+++DV + VL H V F+ + ++ S D+S+
Sbjct: 285 CLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLM--VTCSKDRSI 342
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K++ + E + T+N
Sbjct: 343 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGH 402
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 403 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 459
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 460 AYDGKIKVWDL 470
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/195 (24%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D +++G+ + ++K++D S L+V TGHTG V D+ I++ S D +V
Sbjct: 245 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCLQYDERVIVTGSSDSTV 302
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A S ++++ S D ++ ++D S I +
Sbjct: 303 RVWDVNTGEVLNTLIHHNE---AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVL 359
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW + + + ++ H + + L+ +
Sbjct: 360 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWST-STCEFVRTLNGHKRGIACLQY--RDRL 415
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 416 VVSGSSDNTIRLWDI 430
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/184 (23%), Positives = 85/184 (46%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KIIS D S+ +WD ++ E + HT + +I++GS D TV+++
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV---LCLQYDERVIVTGSSDSTVRVW 305
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H + L +G + + I VWD+ + + L + H+
Sbjct: 306 DVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAA 365
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K++ ST + V ++ ++ + D ++ G D
Sbjct: 366 VNV-VDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 423
Query: 316 IISI 319
I +
Sbjct: 424 TIRL 427
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V+ T + ++ C +
Sbjct: 358 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGI--ACLQYRD 413
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 414 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 470
Score = 39.5 bits (88), Expect = 0.029
Identities = 24/106 (22%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
D + +V+ + +K++ + +R GH + + +D+L ++S S D ++ LWD
Sbjct: 372 DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY-RDRL-VVSGSSDNTIRLWD 429
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRS 200
I + H + +R I+SG+YD +K++D ++
Sbjct: 430 IECGACLRVLEGHEELVRC---IRFDNKRIVSGAYDGKIKVWDLQA 472
Score = 38.7 bits (86), Expect = 0.050
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQ---------SKNVLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+Q S LR H+G V R F D+ +I
Sbjct: 448 CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQF--DEFQI 505
Query: 142 ISYSDDKSVGLWD 154
IS S D ++ +WD
Sbjct: 506 ISSSHDDTILIWD 518
>AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform B protein.
Length = 529
Score = 66.9 bits (156), Expect = 2e-10
Identities = 45/191 (23%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R++V G ++ V+++DV + VL H V F+ + ++ S D+S+
Sbjct: 272 CLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLM--VTCSKDRSI 329
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K++ + E + T+N
Sbjct: 330 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGH 389
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 390 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 446
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 447 AYDGKIKVWDL 457
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/195 (24%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D +++G+ + ++K++D S L+V TGHTG V D+ I++ S D +V
Sbjct: 232 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCLQYDERVIVTGSSDSTV 289
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A S ++++ S D ++ ++D S I +
Sbjct: 290 RVWDVNTGEVLNTLIHHNE---AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVL 346
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW + + + ++ H + + L+ +
Sbjct: 347 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWST-STCEFVRTLNGHKRGIACLQY--RDRL 402
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 403 VVSGSSDNTIRLWDI 417
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/184 (23%), Positives = 85/184 (46%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KIIS D S+ +WD ++ E + HT + +I++GS D TV+++
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV---LCLQYDERVIVTGSSDSTVRVW 292
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H + L +G + + I VWD+ + + L + H+
Sbjct: 293 DVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAA 352
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K++ ST + V ++ ++ + D ++ G D
Sbjct: 353 VNV-VDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 410
Query: 316 IISI 319
I +
Sbjct: 411 TIRL 414
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V+ T + ++ C +
Sbjct: 345 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGI--ACLQYRD 400
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 401 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 457
Score = 39.5 bits (88), Expect = 0.029
Identities = 24/106 (22%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
D + +V+ + +K++ + +R GH + + +D+L ++S S D ++ LWD
Sbjct: 359 DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY-RDRL-VVSGSSDNTIRLWD 416
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRS 200
I + H + +R I+SG+YD +K++D ++
Sbjct: 417 IECGACLRVLEGHEELVRC---IRFDNKRIVSGAYDGKIKVWDLQA 459
Score = 38.7 bits (86), Expect = 0.050
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQ---------SKNVLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+Q S LR H+G V R F D+ +I
Sbjct: 435 CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQF--DEFQI 492
Query: 142 ISYSDDKSVGLWD 154
IS S D ++ +WD
Sbjct: 493 ISSSHDDTILIWD 505
>AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform A protein.
Length = 508
Score = 66.9 bits (156), Expect = 2e-10
Identities = 45/191 (23%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R++V G ++ V+++DV + VL H V F+ + ++ S D+S+
Sbjct: 251 CLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLM--VTCSKDRSI 308
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K++ + E + T+N
Sbjct: 309 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGH 368
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 369 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 425
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 426 AYDGKIKVWDL 436
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/195 (24%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D +++G+ + ++K++D S L+V TGHTG V D+ I++ S D +V
Sbjct: 211 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCLQYDERVIVTGSSDSTV 268
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A S ++++ S D ++ ++D S I +
Sbjct: 269 RVWDVNTGEVLNTLIHHNE---AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVL 325
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW + + + ++ H + + L+ +
Sbjct: 326 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWST-STCEFVRTLNGHKRGIACLQY--RDRL 381
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 382 VVSGSSDNTIRLWDI 396
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/184 (23%), Positives = 85/184 (46%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KIIS D S+ +WD ++ E + HT + +I++GS D TV+++
Sbjct: 215 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV---LCLQYDERVIVTGSSDSTVRVW 271
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H + L +G + + I VWD+ + + L + H+
Sbjct: 272 DVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAA 331
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K++ ST + V ++ ++ + D ++ G D
Sbjct: 332 VNV-VDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 389
Query: 316 IISI 319
I +
Sbjct: 390 TIRL 393
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V+ T + ++ C +
Sbjct: 324 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGI--ACLQYRD 379
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 380 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 436
Score = 39.5 bits (88), Expect = 0.029
Identities = 24/106 (22%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
D + +V+ + +K++ + +R GH + + +D+L ++S S D ++ LWD
Sbjct: 338 DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY-RDRL-VVSGSSDNTIRLWD 395
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRS 200
I + H + +R I+SG+YD +K++D ++
Sbjct: 396 IECGACLRVLEGHEELVRC---IRFDNKRIVSGAYDGKIKVWDLQA 438
Score = 38.7 bits (86), Expect = 0.050
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQ---------SKNVLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+Q S LR H+G V R F D+ +I
Sbjct: 414 CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQF--DEFQI 471
Query: 142 ISYSDDKSVGLWD 154
IS S D ++ +WD
Sbjct: 472 ISSSHDDTILIWD 484
>AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein.
Length = 550
Score = 66.9 bits (156), Expect = 2e-10
Identities = 45/191 (23%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R++V G ++ V+++DV + VL H V F+ + ++ S D+S+
Sbjct: 293 CLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLM--VTCSKDRSI 350
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K++ + E + T+N
Sbjct: 351 AVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGH 410
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 411 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 467
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 468 AYDGKIKVWDL 478
Score = 64.1 bits (149), Expect = 1e-09
Identities = 47/195 (24%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D +++G+ + ++K++D S L+V TGHTG V D+ I++ S D +V
Sbjct: 253 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCLQYDERVIVTGSSDSTV 310
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A S ++++ S D ++ ++D S I +
Sbjct: 311 RVWDVNTGEVLNTLIHHNE---AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVL 367
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW + + + ++ H + + L+ +
Sbjct: 368 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWST-STCEFVRTLNGHKRGIACLQY--RDRL 423
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 424 VVSGSSDNTIRLWDI 438
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/184 (23%), Positives = 85/184 (46%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KIIS D S+ +WD ++ E + HT + +I++GS D TV+++
Sbjct: 257 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV---LCLQYDERVIVTGSSDSTVRVW 313
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H + L +G + + I VWD+ + + L + H+
Sbjct: 314 DVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAA 373
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K++ ST + V ++ ++ + D ++ G D
Sbjct: 374 VNV-VDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 431
Query: 316 IISI 319
I +
Sbjct: 432 TIRL 435
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V+ T + ++ C +
Sbjct: 366 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGI--ACLQYRD 421
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 422 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 478
Score = 39.5 bits (88), Expect = 0.029
Identities = 24/106 (22%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 95 DGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
D + +V+ + +K++ + +R GH + + +D+L ++S S D ++ LWD
Sbjct: 380 DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY-RDRL-VVSGSSDNTIRLWD 437
Query: 155 ISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRS 200
I + H + +R I+SG+YD +K++D ++
Sbjct: 438 IECGACLRVLEGHEELVRC---IRFDNKRIVSGAYDGKIKVWDLQA 480
Score = 38.7 bits (86), Expect = 0.050
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQ---------SKNVLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+Q S LR H+G V R F D+ +I
Sbjct: 456 CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQF--DEFQI 513
Query: 142 ISYSDDKSVGLWD 154
IS S D ++ +WD
Sbjct: 514 ISSSHDDTILIWD 526
>L07758-1|AAA65201.1| 501|Homo sapiens IEF SSP 9502 protein.
Length = 501
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/180 (28%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 124 GHTGPVHRTFFTKDQLKII-SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
GHT V + K ++ S S D +V LWD+S + A+ HTD ++ P
Sbjct: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
Query: 183 IILSGSYDHTVKLYDCRS-NETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI-FN 240
++SGSYD +V LYDCRS +E+ +E + A + V+++
Sbjct: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDAR 373
Query: 241 GGKLLSNISQHHKTVTTLRLASN-NSRLMSASLDRHVKIYDV--STFKVVHNIDFPNAIL 297
K + ++ H+ ++ L L+S L++AS D++VKI+D+ +VH+ D +L
Sbjct: 374 SDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKMGVL 433
>BC001652-1|AAH01652.1| 501|Homo sapiens PWP1 homolog (S.
cerevisiae) protein.
Length = 501
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/180 (28%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 124 GHTGPVHRTFFTKDQLKII-SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
GHT V + K ++ S S D +V LWD+S + A+ HTD ++ P
Sbjct: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
Query: 183 IILSGSYDHTVKLYDCRS-NETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI-FN 240
++SGSYD +V LYDCRS +E+ +E + A + V+++
Sbjct: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDAR 373
Query: 241 GGKLLSNISQHHKTVTTLRLASN-NSRLMSASLDRHVKIYDV--STFKVVHNIDFPNAIL 297
K + ++ H+ ++ L L+S L++AS D++VKI+D+ +VH+ D +L
Sbjct: 374 SDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKMGVL 433
>AK223162-1|BAD96882.1| 501|Homo sapiens nuclear phosphoprotein
similar to S. cerevisiae PWP1 variant protein.
Length = 501
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/180 (28%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 124 GHTGPVHRTFFTKDQLKII-SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
GHT V + K ++ S S D +V LWD+S + A+ HTD ++ P
Sbjct: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
Query: 183 IILSGSYDHTVKLYDCRS-NETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI-FN 240
++SGSYD +V LYDCRS +E+ +E + A + V+++
Sbjct: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDAR 373
Query: 241 GGKLLSNISQHHKTVTTLRLASN-NSRLMSASLDRHVKIYDV--STFKVVHNIDFPNAIL 297
K + ++ H+ ++ L L+S L++AS D++VKI+D+ +VH+ D +L
Sbjct: 374 SDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKMGVL 433
>AF492460-1|AAN64030.1| 1322|Homo sapiens WD repeat 17 protein.
Length = 1322
Score = 66.5 bits (155), Expect = 2e-10
Identities = 46/161 (28%), Positives = 84/161 (52%), Gaps = 8/161 (4%)
Query: 86 AAYGGCFRADGR--LLVAGIEEAAVKLFDV--QSKNVLRVFTGHTGPVHRTFFTKDQLKI 141
AA GC + ++ G E+ V+++ V S L+VF+GHT V ++ + I
Sbjct: 522 AAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGI 581
Query: 142 I-SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRS 200
+ S SDD +V +WD + + I N HT +R + P +++SGS+D+T+K++D R
Sbjct: 582 LCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE 641
Query: 201 NETIMTV-NHGSPVESTLFLPSGGIFISAGGTE--IKVWDI 238
+ TV +HG+ V PS +++ + +++W +
Sbjct: 642 GTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 682
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/175 (23%), Positives = 79/175 (45%), Gaps = 9/175 (5%)
Query: 147 DKSVGLWDISTEE-RIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM 205
D VGL+D+ ++ H + I P P+++ + S+D T+K++D + +
Sbjct: 371 DGGVGLYDMGAKKWDFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVY 430
Query: 206 TVNHGSPVESTLFLPSGGIFISAGGTEIK---VWDIFNGGKLLSNISQHHKT-VTTLRLA 261
T V +L GG+ AGGT +W++ GK++ ++H + + +
Sbjct: 431 TSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNV-QKGKIIQRFNEHGTNGIFCIAWS 489
Query: 262 SNNS-RLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHD-DILTVGMMD 314
+S R+ + S D I + KV+H P A+ S+++ D++ G D
Sbjct: 490 HKDSKRIATCSSDGFCIIRTIDG-KVLHKYKHPAAVFGCDWSQNNKDMIATGCED 543
Score = 33.5 bits (73), Expect = 1.9
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 239 FNGGKLLSNISQHHKTVTTLRLASNNSRLM-SASLDRHVKIYDVSTFKVVHNIDFPNAI 296
+N KL + +S+H KT+T + +N L S S D V I++V+ KV+ +D I
Sbjct: 70 YNEFKLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGI 128
>CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein.
Length = 305
Score = 66.1 bits (154), Expect = 3e-10
Identities = 37/149 (24%), Positives = 62/149 (41%), Gaps = 1/149 (0%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVK 109
+SP Y + + ++D T + + F D +LLV ++ +K
Sbjct: 156 YSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIK 215
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
++DVQ N+ GH V F D +S S DK+V +WD+ T + F +H D
Sbjct: 216 IYDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCVHTFFDHQD 275
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDC 198
+ + I+ G D + +YDC
Sbjct: 276 QVWGVKYNGNGSKIVSVGD-DQEIHIYDC 303
Score = 58.0 bits (134), Expect = 8e-08
Identities = 37/186 (19%), Positives = 88/186 (47%), Gaps = 4/186 (2%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+A ++L+D+++ ++ F+ D + + + V ++ + + ++ +
Sbjct: 85 DAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSL 144
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGG 223
+ +I + A SP + SG+ D + ++D + + + T+ H P+ S F P
Sbjct: 145 DTRGKFILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQ 203
Query: 224 IFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVS 282
+ ++A IK++D+ + L + H V + +++ +S+S D++VK++DV
Sbjct: 204 LLVTASDDGYIKIYDVQHAN-LAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDVG 262
Query: 283 TFKVVH 288
T VH
Sbjct: 263 TRTCVH 268
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/140 (25%), Positives = 66/140 (47%), Gaps = 4/140 (2%)
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFN-- 240
I S S D ++L+D + + I +++ G PV++ S A GT + +IF
Sbjct: 78 IAASSSLDAHIRLWDLENGKQIKSIDAG-PVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 241 GGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID-FPNAILSM 299
GK ++ K + ++ + + L S ++D + I+D++T K++H ++ I S+
Sbjct: 137 SGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSL 196
Query: 300 AISEHDDILTVGMMDGIISI 319
S +L DG I I
Sbjct: 197 TFSPDSQLLVTASDDGYIKI 216
Score = 47.2 bits (107), Expect = 1e-04
Identities = 37/142 (26%), Positives = 72/142 (50%), Gaps = 6/142 (4%)
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S S D + LWD+ ++I + + A SP S + +G++ V ++ S +
Sbjct: 81 SSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS-QYLATGTHVGKVNIFGVESGK 139
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLR 259
+++ G + S + P G ++++G + I ++DI G KLL + H + +L
Sbjct: 140 KEYSLDTRGKFILSIAYSPDGK-YLASGAIDGIINIFDIATG-KLLHTLEGHAMPIRSLT 197
Query: 260 LASNNSRLMSASLDRHVKIYDV 281
+ ++ L++AS D ++KIYDV
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDV 219
Score = 37.9 bits (84), Expect = 0.087
Identities = 24/107 (22%), Positives = 44/107 (41%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L FSP A+ +++YD +A + F D V+ +
Sbjct: 196 LTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKN 255
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD 154
VK++DV ++ + F H V + + KI+S DD+ + ++D
Sbjct: 256 VKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
>Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats
containing protein protein.
Length = 569
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R+++ G ++ V+++DV + +L H V F + ++ S D+S+
Sbjct: 312 CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM--VTCSKDRSI 369
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K+++ + E + T+N
Sbjct: 370 AVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH 429
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 430 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 486
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 487 AYDGKIKVWDL 497
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/195 (23%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D + +V+G+ + +K++D + R+ TGHTG V D+ II+ S D +V
Sbjct: 272 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV--LCLQYDERVIITGSSDSTV 329
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A + ++++ S D ++ ++D S I +
Sbjct: 330 RVWDVNTGEMLNTLIHHCE---AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 386
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW+ + + + ++ H + + L+ +
Sbjct: 387 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWNT-STCEFVRTLNGHKRGIACLQY--RDRL 442
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 443 VVSGSSDNTIRLWDI 457
Score = 54.4 bits (125), Expect = 9e-07
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KI+S D ++ +WD +T E HT + +I++GS D TV+++
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV---LCLQYDERVIITGSSDSTVRVW 332
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H L +G + + I VWD+ + + L + H+
Sbjct: 333 DVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAA 392
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K+++ ST + V ++ ++ + D ++ G D
Sbjct: 393 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 450
Query: 316 IISI 319
I +
Sbjct: 451 TIRL 454
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V++ T + ++ C +
Sbjct: 385 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGI--ACLQYRD 440
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 441 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 497
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKN---------VLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+ + LR H+G V R F D+ +I
Sbjct: 475 CIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQI 532
Query: 142 ISYSDDKSVGLWD 154
+S S D ++ +WD
Sbjct: 533 VSSSHDDTILIWD 545
>BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R+++ G ++ V+++DV + +L H V F + ++ S D+S+
Sbjct: 348 CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM--VTCSKDRSI 405
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K+++ + E + T+N
Sbjct: 406 AVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH 465
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 466 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 522
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 523 AYDGKIKVWDL 533
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/195 (23%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D + +V+G+ + +K++D + R+ TGHTG V D+ II+ S D +V
Sbjct: 308 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV--LCLQYDERVIITGSSDSTV 365
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A + ++++ S D ++ ++D S I +
Sbjct: 366 RVWDVNTGEMLNTLIHHCE---AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 422
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW+ + + + ++ H + + L+ +
Sbjct: 423 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWNT-STCEFVRTLNGHKRGIACLQY--RDRL 478
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 479 VVSGSSDNTIRLWDI 493
Score = 54.4 bits (125), Expect = 9e-07
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KI+S D ++ +WD +T E HT + +I++GS D TV+++
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV---LCLQYDERVIITGSSDSTVRVW 368
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H L +G + + I VWD+ + + L + H+
Sbjct: 369 DVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAA 428
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K+++ ST + V ++ ++ + D ++ G D
Sbjct: 429 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 486
Query: 316 IISI 319
I +
Sbjct: 487 TIRL 490
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V++ T + ++ C +
Sbjct: 421 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGI--ACLQYRD 476
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 477 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 533
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKN---------VLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+ + LR H+G V R F D+ +I
Sbjct: 511 CIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQI 568
Query: 142 ISYSDDKSVGLWD 154
+S S D ++ +WD
Sbjct: 569 VSSSHDDTILIWD 581
>AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R+++ G ++ V+++DV + +L H V F + ++ S D+S+
Sbjct: 312 CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM--VTCSKDRSI 369
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K+++ + E + T+N
Sbjct: 370 AVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH 429
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 430 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 486
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 487 AYDGKIKVWDL 497
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/195 (23%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D + +V+G+ + +K++D + R+ TGHTG V D+ II+ S D +V
Sbjct: 272 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV--LCLQYDERVIITGSSDSTV 329
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A + ++++ S D ++ ++D S I +
Sbjct: 330 RVWDVNTGEMLNTLIHHCE---AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 386
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW+ + + + ++ H + + L+ +
Sbjct: 387 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWNT-STCEFVRTLNGHKRGIACLQY--RDRL 442
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 443 VVSGSSDNTIRLWDI 457
Score = 54.4 bits (125), Expect = 9e-07
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KI+S D ++ +WD +T E HT + +I++GS D TV+++
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV---LCLQYDERVIITGSSDSTVRVW 332
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H L +G + + I VWD+ + + L + H+
Sbjct: 333 DVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAA 392
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K+++ ST + V ++ ++ + D ++ G D
Sbjct: 393 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 450
Query: 316 IISI 319
I +
Sbjct: 451 TIRL 454
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V++ T + ++ C +
Sbjct: 385 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGI--ACLQYRD 440
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 441 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 497
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKN---------VLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+ + LR H+G V R F D+ +I
Sbjct: 475 CIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQI 532
Query: 142 ISYSDDKSVGLWD 154
+S S D ++ +WD
Sbjct: 533 VSSSHDDTILIWD 545
>AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R+++ G ++ V+++DV + +L H V F + ++ S D+S+
Sbjct: 348 CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM--VTCSKDRSI 405
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K+++ + E + T+N
Sbjct: 406 AVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH 465
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 466 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 522
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 523 AYDGKIKVWDL 533
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/195 (23%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D + +V+G+ + +K++D + R+ TGHTG V D+ II+ S D +V
Sbjct: 308 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV--LCLQYDERVIITGSSDSTV 365
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A + ++++ S D ++ ++D S I +
Sbjct: 366 RVWDVNTGEMLNTLIHHCE---AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 422
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW+ + + + ++ H + + L+ +
Sbjct: 423 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWNT-STCEFVRTLNGHKRGIACLQY--RDRL 478
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 479 VVSGSSDNTIRLWDI 493
Score = 54.4 bits (125), Expect = 9e-07
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KI+S D ++ +WD +T E HT + +I++GS D TV+++
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV---LCLQYDERVIITGSSDSTVRVW 368
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H L +G + + I VWD+ + + L + H+
Sbjct: 369 DVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAA 428
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K+++ ST + V ++ ++ + D ++ G D
Sbjct: 429 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 486
Query: 316 IISI 319
I +
Sbjct: 487 TIRL 490
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V++ T + ++ C +
Sbjct: 421 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGI--ACLQYRD 476
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 477 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 533
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKN---------VLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+ + LR H+G V R F D+ +I
Sbjct: 511 CIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQI 568
Query: 142 ISYSDDKSVGLWD 154
+S S D ++ +WD
Sbjct: 569 VSSSHDDTILIWD 581
>AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R+++ G ++ V+++DV + +L H V F + ++ S D+S+
Sbjct: 312 CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM--VTCSKDRSI 369
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K+++ + E + T+N
Sbjct: 370 AVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH 429
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 430 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 486
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 487 AYDGKIKVWDL 497
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/195 (23%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D + +V+G+ + +K++D + R+ TGHTG V D+ II+ S D +V
Sbjct: 272 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV--LCLQYDERVIITGSSDSTV 329
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A + ++++ S D ++ ++D S I +
Sbjct: 330 RVWDVNTGEMLNTLIHHCE---AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 386
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW+ + + + ++ H + + L+ +
Sbjct: 387 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWNT-STCEFVRTLNGHKRGIACLQY--RDRL 442
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 443 VVSGSSDNTIRLWDI 457
Score = 54.4 bits (125), Expect = 9e-07
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KI+S D ++ +WD +T E HT + +I++GS D TV+++
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV---LCLQYDERVIITGSSDSTVRVW 332
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H L +G + + I VWD+ + + L + H+
Sbjct: 333 DVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAA 392
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K+++ ST + V ++ ++ + D ++ G D
Sbjct: 393 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 450
Query: 316 IISI 319
I +
Sbjct: 451 TIRL 454
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V++ T + ++ C +
Sbjct: 385 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGI--ACLQYRD 440
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 441 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 497
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKN---------VLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+ + LR H+G V R F D+ +I
Sbjct: 475 CIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQI 532
Query: 142 ISYSDDKSVGLWD 154
+S S D ++ +WD
Sbjct: 533 VSSSHDDTILIWD 545
>AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R+++ G ++ V+++DV + +L H V F + ++ S D+S+
Sbjct: 348 CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM--VTCSKDRSI 405
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K+++ + E + T+N
Sbjct: 406 AVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH 465
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 466 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 522
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 523 AYDGKIKVWDL 533
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/195 (23%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D + +V+G+ + +K++D + R+ TGHTG V D+ II+ S D +V
Sbjct: 308 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV--LCLQYDERVIITGSSDSTV 365
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A + ++++ S D ++ ++D S I +
Sbjct: 366 RVWDVNTGEMLNTLIHHCE---AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 422
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW+ + + + ++ H + + L+ +
Sbjct: 423 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWNT-STCEFVRTLNGHKRGIACLQY--RDRL 478
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 479 VVSGSSDNTIRLWDI 493
Score = 54.4 bits (125), Expect = 9e-07
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KI+S D ++ +WD +T E HT + +I++GS D TV+++
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV---LCLQYDERVIITGSSDSTVRVW 368
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H L +G + + I VWD+ + + L + H+
Sbjct: 369 DVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAA 428
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K+++ ST + V ++ ++ + D ++ G D
Sbjct: 429 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 486
Query: 316 IISI 319
I +
Sbjct: 487 TIRL 490
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V++ T + ++ C +
Sbjct: 421 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGI--ACLQYRD 476
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 477 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 533
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKN---------VLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+ + LR H+G V R F D+ +I
Sbjct: 511 CIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQI 568
Query: 142 ISYSDDKSVGLWD 154
+S S D ++ +WD
Sbjct: 569 VSSSHDDTILIWD 581
>AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R+++ G ++ V+++DV + +L H V F + ++ S D+S+
Sbjct: 312 CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM--VTCSKDRSI 369
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K+++ + E + T+N
Sbjct: 370 AVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH 429
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 430 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 486
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 487 AYDGKIKVWDL 497
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/195 (23%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D + +V+G+ + +K++D + R+ TGHTG V D+ II+ S D +V
Sbjct: 272 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV--LCLQYDERVIITGSSDSTV 329
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A + ++++ S D ++ ++D S I +
Sbjct: 330 RVWDVNTGEMLNTLIHHCE---AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 386
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW+ + + + ++ H + + L+ +
Sbjct: 387 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWNT-STCEFVRTLNGHKRGIACLQY--RDRL 442
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 443 VVSGSSDNTIRLWDI 457
Score = 54.4 bits (125), Expect = 9e-07
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KI+S D ++ +WD +T E HT + +I++GS D TV+++
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV---LCLQYDERVIITGSSDSTVRVW 332
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H L +G + + I VWD+ + + L + H+
Sbjct: 333 DVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAA 392
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K+++ ST + V ++ ++ + D ++ G D
Sbjct: 393 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 450
Query: 316 IISI 319
I +
Sbjct: 451 TIRL 454
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V++ T + ++ C +
Sbjct: 385 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGI--ACLQYRD 440
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 441 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 497
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKN---------VLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+ + LR H+G V R F D+ +I
Sbjct: 475 CIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQI 532
Query: 142 ISYSDDKSVGLWD 154
+S S D ++ +WD
Sbjct: 533 VSSSHDDTILIWD 545
>AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R+++ G ++ V+++DV + +L H V F + ++ S D+S+
Sbjct: 348 CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM--VTCSKDRSI 405
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K+++ + E + T+N
Sbjct: 406 AVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH 465
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 466 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 522
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 523 AYDGKIKVWDL 533
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/195 (23%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D + +V+G+ + +K++D + R+ TGHTG V D+ II+ S D +V
Sbjct: 308 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV--LCLQYDERVIITGSSDSTV 365
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A + ++++ S D ++ ++D S I +
Sbjct: 366 RVWDVNTGEMLNTLIHHCE---AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 422
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW+ + + + ++ H + + L+ +
Sbjct: 423 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWNT-STCEFVRTLNGHKRGIACLQY--RDRL 478
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 479 VVSGSSDNTIRLWDI 493
Score = 54.4 bits (125), Expect = 9e-07
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KI+S D ++ +WD +T E HT + +I++GS D TV+++
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV---LCLQYDERVIITGSSDSTVRVW 368
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H L +G + + I VWD+ + + L + H+
Sbjct: 369 DVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAA 428
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K+++ ST + V ++ ++ + D ++ G D
Sbjct: 429 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 486
Query: 316 IISI 319
I +
Sbjct: 487 TIRL 490
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V++ T + ++ C +
Sbjct: 421 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGI--ACLQYRD 476
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 477 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 533
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKN---------VLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+ + LR H+G V R F D+ +I
Sbjct: 511 CIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQI 568
Query: 142 ISYSDDKSVGLWD 154
+S S D ++ +WD
Sbjct: 569 VSSSHDDTILIWD 581
>AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1
isoform 1 variant protein.
Length = 421
Score = 65.7 bits (153), Expect = 4e-10
Identities = 39/154 (25%), Positives = 79/154 (51%), Gaps = 4/154 (2%)
Query: 130 HRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSY 189
HR F +DQL + + ++ + +WD+ T + + N +HT+ +R +P I++S S
Sbjct: 132 HRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASR 191
Query: 190 DHTVKLYDCRSNETIMTV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLS 246
D T++++D + + +M V H + V S F P + S G ++ + +W++ + ++
Sbjct: 192 DKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNM-DKYTMIR 250
Query: 247 NISQHHKTVTTLRLASNNSRLMSASLDRHVKIYD 280
+ H V + + + L +AS D V I+D
Sbjct: 251 KLEGRHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 57.2 bits (132), Expect = 1e-07
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 9/159 (5%)
Query: 65 RVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRL-LVAGIEEAAVKLFDVQSK-NVLRVF 122
R++++D T + N+ E F DG L LV+ + ++++D++ N+++V
Sbjct: 151 RIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVL 210
Query: 123 TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF-NEHTDYIRAGAASPISP 181
GH V+ F+ D + S K+V LW++ I H D + A SP
Sbjct: 211 RGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGRHHDVV----ACDFSP 266
Query: 182 D--IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLF 218
D ++ + SYD V ++D + + +M H P + +F
Sbjct: 267 DGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIF 305
Score = 52.0 bits (119), Expect = 5e-06
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 5/158 (3%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKD-QLKIISYSDDKSV 150
F D LL G+ +K++DV + +L HT V F D L ++S S DK++
Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTL 195
Query: 151 GLWDISTEERIAN-FNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+WD+ + + H +++ + A SP S ++ S V L++ I +
Sbjct: 196 RVWDLKDDGNMMKVLRGHQNWVYSCAFSPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEG 254
Query: 209 HGSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLL 245
V + F P G + +A T + +WD NG L+
Sbjct: 255 RHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
>AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A
protein.
Length = 569
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R+++ G ++ V+++DV + +L H V F + ++ S D+S+
Sbjct: 312 CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM--VTCSKDRSI 369
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K+++ + E + T+N
Sbjct: 370 AVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH 429
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 430 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 486
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 487 AYDGKIKVWDL 497
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/195 (23%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D + +V+G+ + +K++D + R+ TGHTG V D+ II+ S D +V
Sbjct: 272 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV--LCLQYDERVIITGSSDSTV 329
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A + ++++ S D ++ ++D S I +
Sbjct: 330 RVWDVNTGEMLNTLIHHCE---AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 386
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW+ + + + ++ H + + L+ +
Sbjct: 387 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWNT-STCEFVRTLNGHKRGIACLQY--RDRL 442
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 443 VVSGSSDNTIRLWDI 457
Score = 54.4 bits (125), Expect = 9e-07
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KI+S D ++ +WD +T E HT + +I++GS D TV+++
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV---LCLQYDERVIITGSSDSTVRVW 332
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H L +G + + I VWD+ + + L + H+
Sbjct: 333 DVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAA 392
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K+++ ST + V ++ ++ + D ++ G D
Sbjct: 393 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 450
Query: 316 IISI 319
I +
Sbjct: 451 TIRL 454
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V++ T + ++ C +
Sbjct: 385 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGI--ACLQYRD 440
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 441 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 497
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKN---------VLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+ + LR H+G V R F D+ +I
Sbjct: 475 CIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQI 532
Query: 142 ISYSDDKSVGLWD 154
+S S D ++ +WD
Sbjct: 533 VSSSHDDTILIWD 545
>AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant
E3RS-IkappaB protein.
Length = 605
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 5/191 (2%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D R+++ G ++ V+++DV + +L H V F + ++ S D+S+
Sbjct: 348 CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM--VTCSKDRSI 405
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHG 210
+WD+++ I + A I+S S D T+K+++ + E + T+N
Sbjct: 406 AVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH 465
Query: 211 SPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA 270
+ L + + I++WDI G L + H + V +R +N R++S
Sbjct: 466 KRGIACLQYRDRLVVSGSSDNTIRLWDI-ECGACLRVLEGHEELVRCIRF--DNKRIVSG 522
Query: 271 SLDRHVKIYDV 281
+ D +K++D+
Sbjct: 523 AYDGKIKVWDL 533
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/195 (23%), Positives = 95/195 (48%), Gaps = 13/195 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + D + +V+G+ + +K++D + R+ TGHTG V D+ II+ S D +V
Sbjct: 308 CLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV--LCLQYDERVIITGSSDSTV 365
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETI----MT 206
+WD++T E + H + A + ++++ S D ++ ++D S I +
Sbjct: 366 RVWDVNTGEMLNTLIHHCE---AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 422
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSR 266
V H + V F I ++G IKVW+ + + + ++ H + + L+ +
Sbjct: 423 VGHRAAVNVVDF-DDKYIVSASGDRTIKVWNT-STCEFVRTLNGHKRGIACLQY--RDRL 478
Query: 267 LMSASLDRHVKIYDV 281
++S S D ++++D+
Sbjct: 479 VVSGSSDNTIRLWDI 493
Score = 54.4 bits (125), Expect = 9e-07
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D KI+S D ++ +WD +T E HT + +I++GS D TV+++
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSV---LCLQYDERVIITGSSDSTVRVW 368
Query: 197 DCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKL-LSNISQHHKTV 255
D + E + T+ H L +G + + I VWD+ + + L + H+
Sbjct: 369 DVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAA 428
Query: 256 TTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMDG 315
+ + ++ ++SAS DR +K+++ ST + V ++ ++ + D ++ G D
Sbjct: 429 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIA-CLQYRDRLVVSGSSDN 486
Query: 316 IISI 319
I +
Sbjct: 487 TIRL 490
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 37 VLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADG 96
VLV A++ +DF + Y +A+ ++V++ T + ++ C +
Sbjct: 421 VLVGHRAAVNVVDFD--DKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGI--ACLQYRD 476
Query: 97 RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
RL+V+G + ++L+D++ LRV GH V F D +I+S + D + +WD+
Sbjct: 477 RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDL 533
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKN---------VLRVFTGHTGPVHRTFFTKDQLKI 141
C R D + +V+G + +K++D+ + LR H+G V R F D+ +I
Sbjct: 511 CIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQF--DEFQI 568
Query: 142 ISYSDDKSVGLWD 154
+S S D ++ +WD
Sbjct: 569 VSSSHDDTILIWD 581
>BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 4 protein.
Length = 340
Score = 64.9 bits (151), Expect = 7e-10
Identities = 48/198 (24%), Positives = 87/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGH+G V + D +S +
Sbjct: 145 YLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWDI +F H I A + P + +GS D T +L+D R+++ ++
Sbjct: 205 DASSKLWDIRDGMCRQSFTGHVSDINAVSFFP-NGYAFATGSDDATCRLFDLRADQELLL 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D ++I++
Sbjct: 323 DGMAVATGSWDSFLRIWN 340
Score = 52.0 bits (119), Expect = 5e-06
Identities = 36/167 (21%), Positives = 72/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI + + + H V +L L+ + +S + D K++D+
Sbjct: 168 LWDI-ETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDI 213
>AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 varia
protein.
Length = 317
Score = 64.9 bits (151), Expect = 7e-10
Identities = 50/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD FN GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWD-FNEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 61.3 bits (142), Expect = 8e-09
Identities = 51/188 (27%), Positives = 87/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D + K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 54.8 bits (126), Expect = 7e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDFNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide binding
protein beta subunit 4 protein.
Length = 340
Score = 64.9 bits (151), Expect = 7e-10
Identities = 48/198 (24%), Positives = 87/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGH+G V + D +S +
Sbjct: 145 YLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWDI +F H I A + P + +GS D T +L+D R+++ ++
Sbjct: 205 DASSKLWDIRDGMCRQSFTGHVSDINAVSFFP-NGYAFATGSDDATCRLFDLRADQELLL 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D ++I++
Sbjct: 323 DGMAVATGSWDSFLRIWN 340
Score = 52.0 bits (119), Expect = 5e-06
Identities = 36/167 (21%), Positives = 72/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI + + + H V +L L+ + +S + D K++D+
Sbjct: 168 LWDI-ETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDI 213
>M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.3
protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 191
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 248
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 249 CAATGPSIKIWDL 261
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 57 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 117 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 176 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 234
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 235 IINALCFS 242
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 261
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 13 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 73 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 132 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDG 214
>AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7
protein.
Length = 347
Score = 63.3 bits (147), Expect = 2e-09
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 9/193 (4%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
+DG+ ++G + ++L+D+ + R F GHT V F+ D +I+S S DK++ LW
Sbjct: 103 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 162
Query: 154 D-ISTEERIANFNEHTDYIRAGAASPISPD-IILSGSYDHTVKLYDCRSNETIMT--VNH 209
+ + + H++++ SP S + II+S +D VK+++ +N + T + H
Sbjct: 163 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGH 221
Query: 210 GSPVESTLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + P G + S G + +WD+ N GK L + + S N +
Sbjct: 222 TGYLNTVTVSPDGSLCASGGKDGQAMLWDL-NEGKHLYTLD--GGDIINALCFSPNRYWL 278
Query: 269 SASLDRHVKIYDV 281
A+ +KI+D+
Sbjct: 279 CAATGPSIKIWDL 291
Score = 62.1 bits (144), Expect = 5e-09
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH+ V + D +S S D ++ LWD++T F HT + + A S
Sbjct: 87 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 146
Query: 180 SPDIILSGSYDHTVKLYDCRS--NETIMTVNHGSPVESTLFLP--SGGIFISAGGTE-IK 234
+ I+ SGS D T+KL++ T+ +H V F P S I +S G + +K
Sbjct: 147 NRQIV-SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 205
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPN 294
VW++ N KL +N H + T+ ++ + S S D ++D++ K ++ +D +
Sbjct: 206 VWNLAN-CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD 264
Query: 295 AILSMAIS 302
I ++ S
Sbjct: 265 IINALCFS 272
Score = 55.2 bits (127), Expect = 5e-07
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Query: 66 VQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTG 124
++++D T + + F +D R +V+G + +KL++ V
Sbjct: 117 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 176
Query: 125 HTGPVHRTFFTKDQLK--IISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPD 182
H+ V F+ + I+S DK V +W+++ + N HT Y+ SP
Sbjct: 177 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 235
Query: 183 IILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
+ SG D L+D + + T++ G + + F P+ +A G IK+WD+
Sbjct: 236 LCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDL 291
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 12/203 (5%)
Query: 124 GHTGPVHRTFFTKD-QLKIISYSDDKSVGLWDISTEERIANFNE-----HTDYIRAGAAS 177
GH G V + T I+S S DK++ +W ++ +E + H+ ++ S
Sbjct: 43 GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 102
Query: 178 PISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFISAGGTE-IKV 235
LSGS+D T++L+D + T V H V S F +S + IK+
Sbjct: 103 S-DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 161
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSR--LMSASLDRHVKIYDVSTFKV-VHNIDF 292
W+ K H + V+ +R + N+S ++S D+ VK+++++ K+ ++I
Sbjct: 162 WNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 221
Query: 293 PNAILSMAISEHDDILTVGMMDG 315
+ ++ +S + G DG
Sbjct: 222 TGYLNTVTVSPDGSLCASGGKDG 244
>AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 63.3 bits (147), Expect = 2e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 603 ITNLSCLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1064 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1123
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1124 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1182
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1183 LCFSPDGKMLISAGG-YIKWWNVVTG 1207
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 968 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 1027
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 1028 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1084
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1085 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1143
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1144 TGDDNGEIRIWNVSNGELLH 1163
Score = 41.1 bits (92), Expect = 0.009
Identities = 38/192 (19%), Positives = 87/192 (45%), Gaps = 11/192 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F L V + + V+L++ S++ + GH VH F+ D ++ SDD+++
Sbjct: 848 FSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIR 907
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGS 211
LW+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 908 LWE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LVNGRTGQIDYLT 960
Query: 212 PVESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+
Sbjct: 961 EAQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLI 1019
Query: 269 SASLDRHVKIYD 280
S+S D +++++
Sbjct: 1020 SSSDDAEIQVWN 1031
Score = 37.5 bits (83), Expect = 0.12
Identities = 52/246 (21%), Positives = 101/246 (41%), Gaps = 21/246 (8%)
Query: 45 IDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIE 104
I Y DFSP A V++++ ++ + + +G F DG + +
Sbjct: 843 IQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSD 902
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ ++L+ ++K V + + K ++ ++ ++ V D ++ N
Sbjct: 903 DQTIRLW--ETKKVCK---------NSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLVNG 951
Query: 165 NE-HTDYIRAGAAS--PISPDI--ILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLF 218
DY+ S +SP + I G + +++ + +N + H V F
Sbjct: 952 RTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQF 1011
Query: 219 LPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVK 277
IS+ EI+VW+ + K + + H +TV RL NSRL+S S D VK
Sbjct: 1012 TADEKTLISSSDDAEIQVWN-WQLDKCIF-LRGHQETVKDFRLL-KNSRLLSWSFDGTVK 1068
Query: 278 IYDVST 283
++++ T
Sbjct: 1069 VWNIIT 1074
Score = 37.1 bits (82), Expect = 0.15
Identities = 27/109 (24%), Positives = 55/109 (50%), Gaps = 7/109 (6%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVL-RVFTGHTGPVHRTFFT-KDQLKIISYSDDKSV 150
ADG R++VA + + LF + + +L + TGH + F+ ++ L +++ S V
Sbjct: 808 ADGARIMVAAKNK--IFLFAIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQ-YCV 864
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
LW+ + ++A+ H ++ SP L+ S D T++L++ +
Sbjct: 865 ELWNTDSRSKVADCRGHLSWVHGVMFSP-DGSSFLTSSDDQTIRLWETK 912
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYD 696
>BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 62.9 bits (146), Expect = 3e-09
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ VF GHTG + D IS +
Sbjct: 145 YLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + I +GS D + +L+D R+++ ++
Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFP-NGEAICTGSDDASCRLFDLRADQELIC 263
Query: 207 VNHGS---PVESTLFLPSGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H S + S F SG +F VWD + + +S H V+ L + +
Sbjct: 264 FSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSER-VGILSGHDNRVSCLGVTA 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 12/210 (5%)
Query: 77 AKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTK 136
A+ + K + A C LV+G+E V ++++ LR GH ++ +
Sbjct: 11 AEQLKKQIADARKACADVTLAELVSGLE--VVGRVQMRTRRTLR---GHLAKIYAMHWAT 65
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D ++S S D + +WD T ++ + ++ A +P S + + G D+ +Y
Sbjct: 66 DSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP-SGNFVACGGLDNMCSIY 124
Query: 197 DCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQH 251
+ +S E + V+ H + FL I S+G T +WDI G + + H
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVG-H 183
Query: 252 HKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+L ++ + + +S + D K++DV
Sbjct: 184 TGDCMSLAVSPDFNLFISGACDASAKLWDV 213
>BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 62.9 bits (146), Expect = 3e-09
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ VF GHTG + D IS +
Sbjct: 145 YLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + I +GS D + +L+D R+++ ++
Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFP-NGEAICTGSDDASCRLFDLRADQELIC 263
Query: 207 VNHGS---PVESTLFLPSGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H S + S F SG +F VWD + + +S H V+ L + +
Sbjct: 264 FSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSER-VGILSGHDNRVSCLGVTA 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 12/210 (5%)
Query: 77 AKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTK 136
A+ + K + A C LV+G+E V ++++ LR GH ++ +
Sbjct: 11 AEQLKKQIADARKACADVTLAELVSGLE--VVGRVQMRTRRTLR---GHLAKIYAMHWAT 65
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D ++S S D + +WD T ++ + ++ A +P S + + G D+ +Y
Sbjct: 66 DSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP-SGNFVACGGLDNMCSIY 124
Query: 197 DCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQH 251
+ +S E + V+ H + FL I S+G T +WDI G + + H
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVG-H 183
Query: 252 HKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+L ++ + + +S + D K++DV
Sbjct: 184 TGDCMSLAVSPDFNLFISGACDASAKLWDV 213
>BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 62.9 bits (146), Expect = 3e-09
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ VF GHTG + D IS +
Sbjct: 145 YLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + I +GS D + +L+D R+++ ++
Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFP-NGEAICTGSDDASCRLFDLRADQELIC 263
Query: 207 VNHGS---PVESTLFLPSGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H S + S F SG +F VWD + + +S H V+ L + +
Sbjct: 264 FSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSER-VGILSGHDNRVSCLGVTA 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 12/210 (5%)
Query: 77 AKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTK 136
A+ + K + A C LV+G+E V ++++ LR GH ++ +
Sbjct: 11 AEQLKKQIADARKACADVTLAELVSGLE--VVGRVQMRTRRTLR---GHLAKIYAMHWAT 65
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D ++S S D + +WD T ++ + ++ A +P S + + G D+ +Y
Sbjct: 66 DSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP-SGNFVACGGLDNMCSIY 124
Query: 197 DCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQH 251
+ +S E + V+ H + FL I S+G T +WDI G + + H
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVG-H 183
Query: 252 HKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+L ++ + + +S + D K++DV
Sbjct: 184 TGDCMSLAVSPDFNLFISGACDASAKLWDV 213
>AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 603 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1064 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1123
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1124 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1182
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1183 LCFSPDGKMLISAGG-YIKWWNVVTG 1207
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 968 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 1027
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 1028 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1084
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1085 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1143
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1144 TGDDNGEIRIWNVSNGELLH 1163
Score = 41.1 bits (92), Expect = 0.009
Identities = 38/192 (19%), Positives = 87/192 (45%), Gaps = 11/192 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F L V + + V+L++ S++ + GH VH F+ D ++ SDD+++
Sbjct: 848 FSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIR 907
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGS 211
LW+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 908 LWE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLT 960
Query: 212 PVESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+
Sbjct: 961 EAQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLI 1019
Query: 269 SASLDRHVKIYD 280
S+S D +++++
Sbjct: 1020 SSSDDAEIQVWN 1031
Score = 40.3 bits (90), Expect = 0.016
Identities = 28/109 (25%), Positives = 56/109 (51%), Gaps = 7/109 (6%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVL-RVFTGHTGPVHRTFFT-KDQLKIISYSDDKSV 150
ADG R++VA + + LFD+ + +L + TGH + F+ ++ L +++ S V
Sbjct: 808 ADGARIMVAAKNK--IFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQ-YCV 864
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
LW+ + ++A+ H ++ SP L+ S D T++L++ +
Sbjct: 865 ELWNTDSRSKVADCRGHLSWVHGVMFSP-DGSSFLTSSDDQTIRLWETK 912
Score = 37.5 bits (83), Expect = 0.12
Identities = 53/246 (21%), Positives = 101/246 (41%), Gaps = 21/246 (8%)
Query: 45 IDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIE 104
I Y DFSP A V++++ ++ + + +G F DG + +
Sbjct: 843 IQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSD 902
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD-ISTEERIAN 163
+ ++L+ ++K V + + K ++ ++ ++ V D I + I
Sbjct: 903 DQTIRLW--ETKKVCK---------NSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLING 951
Query: 164 FNEHTDYIRAGAAS--PISPDI--ILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLF 218
DY+ S +SP + I G + +++ + +N + H V F
Sbjct: 952 RTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQF 1011
Query: 219 LPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVK 277
IS+ EI+VW+ + K + + H +TV RL NSRL+S S D VK
Sbjct: 1012 TADEKTLISSSDDAEIQVWN-WQLDKCIF-LRGHQETVKDFRLL-KNSRLLSWSFDGTVK 1068
Query: 278 IYDVST 283
++++ T
Sbjct: 1069 VWNIIT 1074
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYD 696
>AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating
factor-1 protein.
Length = 1205
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 603 ITNLSRLVVRPHTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1021 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1080
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1081 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1139
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1140 LCFSPDGKMLISAGG-YIKWWNVVTG 1164
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 925 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 984
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 985 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1041
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1042 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1100
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1101 TGDDNGEIRIWNVSNGELLH 1120
Score = 35.1 bits (77), Expect = 0.62
Identities = 41/191 (21%), Positives = 89/191 (46%), Gaps = 14/191 (7%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
ADG R++VA + + D++SK + GH VH F+ D ++ SDD+++ L
Sbjct: 808 ADGARIMVAAKNKIFLWNTDLRSK--VADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 865
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSP 212
W+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 866 WE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLTE 918
Query: 213 VESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+S
Sbjct: 919 AQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLIS 977
Query: 270 ASLDRHVKIYD 280
+S D +++++
Sbjct: 978 SSDDAEIQVWN 988
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYD 696
>AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 603 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1021 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1080
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1081 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1139
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1140 LCFSPDGKMLISAGG-YIKWWNVVTG 1164
Score = 44.4 bits (100), Expect = 0.001
Identities = 43/200 (21%), Positives = 88/200 (44%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V R FT D+ +IS SDD +
Sbjct: 925 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWRIQFTADEKTLISSSDDAEI 984
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 985 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNPRLLSWSFDGTVKVWNIITGNKEKDFVCH 1041
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1042 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1100
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1101 TGDDNGEIRIWNVSNGELLH 1120
Score = 37.1 bits (82), Expect = 0.15
Identities = 40/191 (20%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
ADG R++VA + + L++ S++ + GH VH F+ D ++ SDD+++ L
Sbjct: 808 ADGARIMVAAKNK--IFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 865
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSP 212
W+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 866 WE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLTE 918
Query: 213 VESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+S
Sbjct: 919 AQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWRIQFTADEKTLIS 977
Query: 270 ASLDRHVKIYD 280
+S D +++++
Sbjct: 978 SSDDAEIQVWN 988
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYD 696
>AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 603 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1021 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1080
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1081 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1139
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1140 LCFSPDGKMLISAGG-YIKWWNVVTG 1164
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 925 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 984
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 985 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1041
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1042 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1100
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1101 TGDDNGEIRIWNVSNGELLH 1120
Score = 36.7 bits (81), Expect = 0.20
Identities = 40/191 (20%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
ADG R++VA + + L++ S++ + GH VH F+ D ++ SDD+++ L
Sbjct: 808 ADGARIMVAAKNK--IFLWNTDSRSKVTDCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 865
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSP 212
W+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 866 WE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLTE 918
Query: 213 VESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+S
Sbjct: 919 AQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLIS 977
Query: 270 ASLDRHVKIYD 280
+S D +++++
Sbjct: 978 SSDDAEIQVWN 988
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYD 696
>AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 603 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1021 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1080
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1081 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1139
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1140 LCFSPDGKMLISAGG-YIKWWNVVTG 1164
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 925 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 984
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 985 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1041
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1042 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1100
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1101 TGDDNGEIRIWNVSNGELLH 1120
Score = 36.7 bits (81), Expect = 0.20
Identities = 40/191 (20%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
ADG R++VA + + L++ S++ + GH VH F+ D ++ SDD+++ L
Sbjct: 808 ADGARIMVAAKNK--IFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 865
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSP 212
W+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 866 WE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLTE 918
Query: 213 VESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+S
Sbjct: 919 AQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLIS 977
Query: 270 ASLDRHVKIYD 280
+S D +++++
Sbjct: 978 SSDDAEIQVWN 988
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYD 696
>AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 603 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1021 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1080
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1081 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1139
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1140 LCFSPDGKMLISAGG-YIKWWNVVTG 1164
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 925 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 984
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 985 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1041
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1042 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1100
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1101 TGDDNGEIRIWNVSNGELLH 1120
Score = 36.7 bits (81), Expect = 0.20
Identities = 40/191 (20%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
ADG R++VA + + L++ S++ + GH VH F+ D ++ SDD+++ L
Sbjct: 808 ADGARIMVAAKNK--IFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 865
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSP 212
W+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 866 WE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLTE 918
Query: 213 VESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+S
Sbjct: 919 AQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLIS 977
Query: 270 ASLDRHVKIYD 280
+S D +++++
Sbjct: 978 SSDDAEIQVWN 988
Score = 35.1 bits (77), Expect = 0.62
Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNIDFPNAILS---MAISEHDDILTVGMMDGIISI 319
+ S+D+ VKI++ T ++VH D + ++ A S H +L G D + +
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFLKL 727
>AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 603 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1064 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1123
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1124 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1182
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1183 LCFSPDGKMLISAGG-YIKWWNVVTG 1207
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 968 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 1027
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 1028 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1084
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1085 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1143
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1144 TGDDNGEIRIWNVSNGELLH 1163
Score = 41.1 bits (92), Expect = 0.009
Identities = 38/192 (19%), Positives = 87/192 (45%), Gaps = 11/192 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F L V + + V+L++ S++ + GH VH F+ D ++ SDD+++
Sbjct: 848 FSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIR 907
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGS 211
LW+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 908 LWE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLT 960
Query: 212 PVESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+
Sbjct: 961 EAQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLI 1019
Query: 269 SASLDRHVKIYD 280
S+S D +++++
Sbjct: 1020 SSSDDAEIQVWN 1031
Score = 40.3 bits (90), Expect = 0.016
Identities = 28/109 (25%), Positives = 56/109 (51%), Gaps = 7/109 (6%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVL-RVFTGHTGPVHRTFFT-KDQLKIISYSDDKSV 150
ADG R++VA + + LFD+ + +L + TGH + F+ ++ L +++ S V
Sbjct: 808 ADGARIMVAAKNK--IFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQ-YCV 864
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
LW+ + ++A+ H ++ SP L+ S D T++L++ +
Sbjct: 865 ELWNTDSRSKVADCRGHLSWVHGVMFSP-DGSSFLTSSDDQTIRLWETK 912
Score = 37.5 bits (83), Expect = 0.12
Identities = 53/246 (21%), Positives = 101/246 (41%), Gaps = 21/246 (8%)
Query: 45 IDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIE 104
I Y DFSP A V++++ ++ + + +G F DG + +
Sbjct: 843 IQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSD 902
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD-ISTEERIAN 163
+ ++L+ ++K V + + K ++ ++ ++ V D I + I
Sbjct: 903 DQTIRLW--ETKKVCK---------NSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLING 951
Query: 164 FNEHTDYIRAGAAS--PISPDI--ILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLF 218
DY+ S +SP + I G + +++ + +N + H V F
Sbjct: 952 RTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQF 1011
Query: 219 LPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVK 277
IS+ EI+VW+ + K + + H +TV RL NSRL+S S D VK
Sbjct: 1012 TADEKTLISSSDDAEIQVWN-WQLDKCIF-LRGHQETVKDFRLL-KNSRLLSWSFDGTVK 1068
Query: 278 IYDVST 283
++++ T
Sbjct: 1069 VWNIIT 1074
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYD 696
>AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease
activating factor-1 long isoform APAF-1L protein.
Length = 1237
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 592 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 651
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 652 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 711
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 712 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 770
Query: 247 NISQ 250
N+ Q
Sbjct: 771 NVKQ 774
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1053 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1112
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1113 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1171
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1172 LCFSPDGKMLISAGG-YIKWWNVVTG 1196
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 957 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 1016
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 1017 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1073
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1074 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1132
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1133 TGDDNGEIRIWNVSNGELLH 1152
Score = 41.1 bits (92), Expect = 0.009
Identities = 38/192 (19%), Positives = 87/192 (45%), Gaps = 11/192 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F L V + + V+L++ S++ + GH VH F+ D ++ SDD+++
Sbjct: 837 FSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIR 896
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGS 211
LW+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 897 LWE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLT 949
Query: 212 PVESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+
Sbjct: 950 EAQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLI 1008
Query: 269 SASLDRHVKIYD 280
S+S D +++++
Sbjct: 1009 SSSDDAEIQVWN 1020
Score = 40.3 bits (90), Expect = 0.016
Identities = 28/109 (25%), Positives = 56/109 (51%), Gaps = 7/109 (6%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVL-RVFTGHTGPVHRTFFT-KDQLKIISYSDDKSV 150
ADG R++VA + + LFD+ + +L + TGH + F+ ++ L +++ S V
Sbjct: 797 ADGARIMVAAKNK--IFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQ-YCV 853
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
LW+ + ++A+ H ++ SP L+ S D T++L++ +
Sbjct: 854 ELWNTDSRSKVADCRGHLSWVHGVMFSP-DGSSFLTSSDDQTIRLWETK 901
Score = 37.5 bits (83), Expect = 0.12
Identities = 53/246 (21%), Positives = 101/246 (41%), Gaps = 21/246 (8%)
Query: 45 IDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIE 104
I Y DFSP A V++++ ++ + + +G F DG + +
Sbjct: 832 IQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSD 891
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD-ISTEERIAN 163
+ ++L+ ++K V + + K ++ ++ ++ V D I + I
Sbjct: 892 DQTIRLW--ETKKVCK---------NSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLING 940
Query: 164 FNEHTDYIRAGAAS--PISPDI--ILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLF 218
DY+ S +SP + I G + +++ + +N + H V F
Sbjct: 941 RTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQF 1000
Query: 219 LPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVK 277
IS+ EI+VW+ + K + + H +TV RL NSRL+S S D VK
Sbjct: 1001 TADEKTLISSSDDAEIQVWN-WQLDKCIF-LRGHQETVKDFRLL-KNSRLLSWSFDGTVK 1057
Query: 278 IYDVST 283
++++ T
Sbjct: 1058 VWNIIT 1063
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 661
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 662 ATCSVDKKVKIWNSMTGELVHTYD 685
>AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1194
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 592 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 651
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 652 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 711
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 712 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 770
Query: 247 NISQ 250
N+ Q
Sbjct: 771 NVKQ 774
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1010 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1069
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1070 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1128
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1129 LCFSPDGKMLISAGG-YIKWWNVVTG 1153
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 914 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 973
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 974 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1030
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1031 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1089
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1090 TGDDNGEIRIWNVSNGELLH 1109
Score = 36.7 bits (81), Expect = 0.20
Identities = 40/191 (20%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
ADG R++VA + + L++ S++ + GH VH F+ D ++ SDD+++ L
Sbjct: 797 ADGARIMVAAKNK--IFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 854
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSP 212
W+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 855 WE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLTE 907
Query: 213 VESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+S
Sbjct: 908 AQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLIS 966
Query: 270 ASLDRHVKIYD 280
+S D +++++
Sbjct: 967 SSDDAEIQVWN 977
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 661
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 662 ATCSVDKKVKIWNSMTGELVHTYD 685
>AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein.
Length = 1237
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 592 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 651
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 652 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 711
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 712 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 770
Query: 247 NISQ 250
N+ Q
Sbjct: 771 NVKQ 774
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1053 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1112
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1113 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1171
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1172 LCFSPDGKMLISAGG-YIKWWNVVTG 1196
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 957 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 1016
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 1017 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1073
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1074 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1132
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1133 TGDDNGEIRIWNVSNGELLH 1152
Score = 41.1 bits (92), Expect = 0.009
Identities = 38/192 (19%), Positives = 87/192 (45%), Gaps = 11/192 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F L V + + V+L++ S++ + GH VH F+ D ++ SDD+++
Sbjct: 837 FSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIR 896
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGS 211
LW+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 897 LWE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLT 949
Query: 212 PVESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+
Sbjct: 950 EAQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLI 1008
Query: 269 SASLDRHVKIYD 280
S+S D +++++
Sbjct: 1009 SSSDDAEIQVWN 1020
Score = 40.3 bits (90), Expect = 0.016
Identities = 28/109 (25%), Positives = 56/109 (51%), Gaps = 7/109 (6%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVL-RVFTGHTGPVHRTFFT-KDQLKIISYSDDKSV 150
ADG R++VA + + LFD+ + +L + TGH + F+ ++ L +++ S V
Sbjct: 797 ADGARIMVAAKNK--IFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQ-YCV 853
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCR 199
LW+ + ++A+ H ++ SP L+ S D T++L++ +
Sbjct: 854 ELWNTDSRSKVADCRGHLSWVHGVMFSP-DGSSFLTSSDDQTIRLWETK 901
Score = 37.5 bits (83), Expect = 0.12
Identities = 53/246 (21%), Positives = 101/246 (41%), Gaps = 21/246 (8%)
Query: 45 IDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIE 104
I Y DFSP A V++++ ++ + + +G F DG + +
Sbjct: 832 IQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSD 891
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD-ISTEERIAN 163
+ ++L+ ++K V + + K ++ ++ ++ V D I + I
Sbjct: 892 DQTIRLW--ETKKVCK---------NSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLING 940
Query: 164 FNEHTDYIRAGAAS--PISPDI--ILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLF 218
DY+ S +SP + I G + +++ + +N + H V F
Sbjct: 941 RTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQF 1000
Query: 219 LPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVK 277
IS+ EI+VW+ + K + + H +TV RL NSRL+S S D VK
Sbjct: 1001 TADEKTLISSSDDAEIQVWN-WQLDKCIF-LRGHQETVKDFRLL-KNSRLLSWSFDGTVK 1057
Query: 278 IYDVST 283
++++ T
Sbjct: 1058 VWNIIT 1063
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 661
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 662 ATCSVDKKVKIWNSMTGELVHTYD 685
>Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-binding
protein beta3 subunit protein.
Length = 340
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ VF GHTG + D IS +
Sbjct: 145 YLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + I +GS D + +L+D R+++ ++
Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFP-NGEAICTGSDDASCRLFDLRADQELIC 263
Query: 207 VNHGS---PVESTLFLPSGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H S + S F SG +F VWD + + +S H V+ L + +
Sbjct: 264 FSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSER-VGILSGHDNRVSCLGVTA 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 12/210 (5%)
Query: 77 AKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTK 136
A+ + K + A C LV+G+E V ++++ LR GH ++ +
Sbjct: 11 AEQLKKQIADARKACADVTLAELVSGLE--VVGRVQMRTRRTLR---GHLAKIYAMHWAT 65
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D ++S S D + +WD T ++ + ++ A +P S + + G D+ +Y
Sbjct: 66 DSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP-SGNFVACGGLDNMCSIY 124
Query: 197 DCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQH 251
+ +S E + V+ H + FL I S+G T +WDI G + + H
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVG-H 183
Query: 252 HKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+L ++ + + +S + D K++DV
Sbjct: 184 TGDCMSLAVSPDFNLFISGACDASAKLWDV 213
>U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain
protein.
Length = 340
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ VF GHTG + D IS +
Sbjct: 145 YLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + I +GS D + +L+D R+++ ++
Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFP-NGEAICTGSDDASCRLFDLRADQELIC 263
Query: 207 VNHGS---PVESTLFLPSGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H S + S F SG +F VWD + + +S H V+ L + +
Sbjct: 264 FSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSER-VGILSGHDNRVSCLGVTA 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 12/210 (5%)
Query: 77 AKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTK 136
A+ + K + A C LV+G+E V ++++ LR GH ++ +
Sbjct: 11 AEQLKKQIADARKACADVTLAELVSGLE--VVGRVQMRTRRTLR---GHLAKIYAMHWAT 65
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D ++S S D + +WD T ++ + ++ A +P S + + G D+ +Y
Sbjct: 66 DSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP-SGNFVACGGLDNMCSIY 124
Query: 197 DCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQH 251
+ +S E + V+ H + FL I S+G T +WDI G + + H
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVG-H 183
Query: 252 HKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+L ++ + + +S + D K++DV
Sbjct: 184 TGDCMSLAVSPDFNLFISGACDASAKLWDV 213
>M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein.
Length = 340
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ VF GHTG + D IS +
Sbjct: 145 YLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + I +GS D + +L+D R+++ ++
Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFP-NGEAICTGSDDASCRLFDLRADQELIC 263
Query: 207 VNHGS---PVESTLFLPSGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H S + S F SG +F VWD + + +S H V+ L + +
Sbjct: 264 FSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSER-VGILSGHDNRVSCLGVTA 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 12/210 (5%)
Query: 77 AKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTK 136
A+ + K + A C LV+G+E V ++++ LR GH ++ +
Sbjct: 11 AEQLKKQIADARKACADVTLAELVSGLE--VVGRVQMRTRRTLR---GHLAKIYAMHWAT 65
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D ++S S D + +WD T ++ + ++ A +P S + + G D+ +Y
Sbjct: 66 DSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP-SGNFVACGGLDNMCSIY 124
Query: 197 DCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQH 251
+ +S E + V+ H + FL I S+G T +WDI G + + H
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVG-H 183
Query: 252 HKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+L ++ + + +S + D K++DV
Sbjct: 184 TGDCMSLAVSPDFNLFISGACDASAKLWDV 213
>AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ VF GHTG + D IS +
Sbjct: 145 YLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + I +GS D + +L+D R+++ ++
Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFP-NGEAICTGSDDASCRLFDLRADQELIC 263
Query: 207 VNHGS---PVESTLFLPSGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H S + S F SG +F VWD + + +S H V+ L + +
Sbjct: 264 FSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSER-VGILSGHDNRVSCLGVTA 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 12/210 (5%)
Query: 77 AKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTK 136
A+ + K + A C LV+G+E V ++++ LR GH ++ +
Sbjct: 11 AEQLKKQIADARKACADVTLAELVSGLE--VVGRVQMRTRRTLR---GHLAKIYAMHWAT 65
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D ++S S D + +WD T ++ + ++ A +P S + + G D+ +Y
Sbjct: 66 DSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP-SGNFVACGGLDNMCSIY 124
Query: 197 DCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQH 251
+ +S E + V+ H + FL I S+G T +WDI G + + H
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVG-H 183
Query: 252 HKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+L ++ + + +S + D K++DV
Sbjct: 184 TGDCMSLAVSPDFNLFISGACDASAKLWDV 213
>AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide binding
protein beta 3 protein.
Length = 340
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ VF GHTG + D IS +
Sbjct: 145 YLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + I +GS D + +L+D R+++ ++
Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFP-NGEAICTGSDDASCRLFDLRADQELIC 263
Query: 207 VNHGS---PVESTLFLPSGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H S + S F SG +F VWD + + +S H V+ L + +
Sbjct: 264 FSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSER-VGILSGHDNRVSCLGVTA 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 12/210 (5%)
Query: 77 AKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTK 136
A+ + K + A C LV+G+E V ++++ LR GH ++ +
Sbjct: 11 AEQLKKQIADARKACADVTLAELVSGLE--VVGRVQMRTRRTLR---GHLAKIYAMHWAT 65
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D ++S S D + +WD T ++ + ++ A +P S + + G D+ +Y
Sbjct: 66 DSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP-SGNFVACGGLDNMCSIY 124
Query: 197 DCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQH 251
+ +S E + V+ H + FL I S+G T +WDI G + + H
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVG-H 183
Query: 252 HKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+L ++ + + +S + D K++DV
Sbjct: 184 TGDCMSLAVSPDFNLFISGACDASAKLWDV 213
>AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-binding
protein, beta-3 subunit variant protein.
Length = 327
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ VF GHTG + D IS +
Sbjct: 132 YLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 191
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + I +GS D + +L+D R+++ ++
Sbjct: 192 DASAKLWDVREGTCRQTFTGHESDINAICFFP-NGEAICTGSDDASCRLFDLRADQELIC 250
Query: 207 VNHGS---PVESTLFLPSGG-IFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H S + S F SG +F VWD + + +S H V+ L + +
Sbjct: 251 FSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSER-VGILSGHDNRVSCLGVTA 309
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 310 DGMAVATGSWDSFLKIWN 327
Score = 55.2 bits (127), Expect = 5e-07
Identities = 43/188 (22%), Positives = 84/188 (44%), Gaps = 12/188 (6%)
Query: 99 LVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTE 158
LV+G+E V ++++ LR GH ++ + D ++S S D + +WD T
Sbjct: 20 LVSGLE--VVGRVQMRTRRTLR---GHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTT 74
Query: 159 ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPV 213
++ + ++ A +P S + + G D+ +Y+ +S E + V+ H +
Sbjct: 75 NKVHAIPLRSSWVMTCAYAP-SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYL 133
Query: 214 ESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLD 273
FL I S+G T +WDI G + + H +L ++ + + +S + D
Sbjct: 134 SCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVG-HTGDCMSLAVSPDFNLFISGACD 192
Query: 274 RHVKIYDV 281
K++DV
Sbjct: 193 ASAKLWDV 200
>BC014988-1|AAH14988.1| 919|Homo sapiens PWP2 periodic tryptophan
protein homolog (yeast) protein.
Length = 919
Score = 62.1 bits (144), Expect = 5e-09
Identities = 59/255 (23%), Positives = 110/255 (43%), Gaps = 16/255 (6%)
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
+++ QS++ + GH + ++ D I++ DD V +W+ + F EH+
Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 416
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFISA 228
+ G + ++++ S D TV+ +D T P + S + + + G +SA
Sbjct: 417 GV-TGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSA 475
Query: 229 GGT---EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV-STF 284
G EI VW + G+LL +S H ++ L S L SAS D+ V+++D+ ++
Sbjct: 476 GAQDSFEIFVWSM-QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSW 534
Query: 285 KVVHNIDFPNAILSMAISEHDDILTVGMMDGIISIRKREEPVRQSE---------KRKNL 335
+ + + L++ I L V ++ I+ E V+ RK L
Sbjct: 535 RTKETLALTSDALAVTIRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKEL 594
Query: 336 LKFIPDHTSQTKADT 350
K H ++ KA T
Sbjct: 595 DKITAKHAAKGKAFT 609
Score = 49.2 bits (112), Expect = 4e-05
Identities = 36/192 (18%), Positives = 84/192 (43%), Gaps = 4/192 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ DG+ +V G ++ VK+++ S FT H+ V FT +++ S D +V
Sbjct: 381 YSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVR 440
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYD-HTVKLYDCRSNETIMTVN-H 209
+D+ F + A S +I+ +G+ D + ++ ++ + ++ H
Sbjct: 441 AFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
P+ F P + SA + +++WD+F+ + ++ + + + + + L
Sbjct: 501 EGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDAL-AVTIRPDGAELA 559
Query: 269 SASLDRHVKIYD 280
A+L+ + +D
Sbjct: 560 VATLNSQITFWD 571
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 79/200 (39%), Gaps = 5/200 (2%)
Query: 42 FGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVA 101
F ++ L +SP Y +V+V++ ++ ++ G F A G ++V
Sbjct: 373 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT 432
Query: 102 GIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS--YSDDKSVGLWDISTEE 159
+ V+ FD+ R FT +I+S D + +W + T
Sbjct: 433 SSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGR 492
Query: 160 RIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLF 218
+ + H I +P+ ++ S S+D TV+L+D S T T+ S +
Sbjct: 493 LLDVLSGHEGPISGLCFNPMK-SVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTI 551
Query: 219 LPSGG-IFISAGGTEIKVWD 237
P G + ++ ++I WD
Sbjct: 552 RPDGAELAVATLNSQITFWD 571
>BC013309-1|AAH13309.1| 919|Homo sapiens PWP2 periodic tryptophan
protein homolog (yeast) protein.
Length = 919
Score = 62.1 bits (144), Expect = 5e-09
Identities = 59/255 (23%), Positives = 110/255 (43%), Gaps = 16/255 (6%)
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
+++ QS++ + GH + ++ D I++ DD V +W+ + F EH+
Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 416
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFISA 228
+ G + ++++ S D TV+ +D T P + S + + + G +SA
Sbjct: 417 GV-TGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSA 475
Query: 229 GGT---EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV-STF 284
G EI VW + G+LL +S H ++ L S L SAS D+ V+++D+ ++
Sbjct: 476 GAQDSFEIFVWSM-QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSW 534
Query: 285 KVVHNIDFPNAILSMAISEHDDILTVGMMDGIISIRKREEPVRQSE---------KRKNL 335
+ + + L++ I L V ++ I+ E V+ RK L
Sbjct: 535 RTKETLALTSDALAVTIRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKEL 594
Query: 336 LKFIPDHTSQTKADT 350
K H ++ KA T
Sbjct: 595 DKITAKHAAKGKAFT 609
Score = 49.2 bits (112), Expect = 4e-05
Identities = 36/192 (18%), Positives = 84/192 (43%), Gaps = 4/192 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ DG+ +V G ++ VK+++ S FT H+ V FT +++ S D +V
Sbjct: 381 YSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVR 440
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYD-HTVKLYDCRSNETIMTVN-H 209
+D+ F + A S +I+ +G+ D + ++ ++ + ++ H
Sbjct: 441 AFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
P+ F P + SA + +++WD+F+ + ++ + + + + + L
Sbjct: 501 EGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDAL-AVTIRPDGAELA 559
Query: 269 SASLDRHVKIYD 280
A+L+ + +D
Sbjct: 560 VATLNSQITFWD 571
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 79/200 (39%), Gaps = 5/200 (2%)
Query: 42 FGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVA 101
F ++ L +SP Y +V+V++ ++ ++ G F A G ++V
Sbjct: 373 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT 432
Query: 102 GIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS--YSDDKSVGLWDISTEE 159
+ V+ FD+ R FT +I+S D + +W + T
Sbjct: 433 SSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGR 492
Query: 160 RIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLF 218
+ + H I +P+ ++ S S+D TV+L+D S T T+ S +
Sbjct: 493 LLDVLSGHEGPISGLCFNPMK-SVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTI 551
Query: 219 LPSGG-IFISAGGTEIKVWD 237
P G + ++ ++I WD
Sbjct: 552 RPDGAELAVATLNSQITFWD 571
>AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 62.1 bits (144), Expect = 5e-09
Identities = 47/184 (25%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + ++F ++ L H V
Sbjct: 603 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTFQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1021 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1080
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1081 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1139
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1140 LCFSPDGKMLISAGG-YIKWWNVVTG 1164
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 925 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 984
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 985 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1041
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1042 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1100
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1101 TGDDNGEIRIWNVSNGELLH 1120
Score = 36.7 bits (81), Expect = 0.20
Identities = 40/191 (20%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
ADG R++VA + + L++ S++ + GH VH F+ D ++ SDD+++ L
Sbjct: 808 ADGARIMVAAKNK--IFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 865
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSP 212
W+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 866 WE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLTE 918
Query: 213 VESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+S
Sbjct: 919 AQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLIS 977
Query: 270 ASLDRHVKIYD 280
+S D +++++
Sbjct: 978 SSDDAEIQVWN 988
Score = 32.7 bits (71), Expect = 3.3
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + +V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTFQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYD 696
>M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transducin
beta-2 subunit mRNA, complete cds. ).
Length = 340
Score = 61.3 bits (142), Expect = 8e-09
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D ++ + L+D+++ F GH+G V D +S +
Sbjct: 145 YLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S+ LWD+ F H I A A P + +GS D T +L+D R+++ ++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFP-NGYAFTTGSDDATCRLFDLRADQELLM 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ +WD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 60.1 bits (139), Expect = 2e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G + + + H V +L LA + +S + D +K++DV
Sbjct: 168 LWDIETGQQTV-GFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 61.3 bits (142), Expect = 8e-09
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D ++ + L+D+++ F GH+G V D +S +
Sbjct: 145 YLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S+ LWD+ F H I A A P + +GS D T +L+D R+++ ++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFP-NGYAFTTGSDDATCRLFDLRADQELLM 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ +WD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 60.1 bits (139), Expect = 2e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G + + + H V +L LA + +S + D +K++DV
Sbjct: 168 LWDIETGQQTV-GFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 61.3 bits (142), Expect = 8e-09
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D ++ + L+D+++ F GH+G V D +S +
Sbjct: 145 YLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S+ LWD+ F H I A A P + +GS D T +L+D R+++ ++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFP-NGYAFTTGSDDATCRLFDLRADQELLM 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ +WD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 60.1 bits (139), Expect = 2e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G + + + H V +L LA + +S + D +K++DV
Sbjct: 168 LWDIETGQQTV-GFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein.
Length = 332
Score = 61.3 bits (142), Expect = 8e-09
Identities = 47/187 (25%), Positives = 78/187 (41%), Gaps = 7/187 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ FTGHTG V D +S +
Sbjct: 145 YLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A P + + +GS D T +L+D R+++ +MT
Sbjct: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELMT 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ VWD + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMS 269
+ + S
Sbjct: 323 DGMAVAS 329
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y+ ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G+ + + H V +L LA + +S + D K++DV
Sbjct: 168 LWDI-ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
>BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 61.3 bits (142), Expect = 8e-09
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D ++ + L+D+++ F GH+G V D +S +
Sbjct: 145 YLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S+ LWD+ F H I A A P + +GS D T +L+D R+++ ++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFP-NGYAFTTGSDDATCRLFDLRADQELLM 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ +WD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 60.1 bits (139), Expect = 2e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G + + + H V +L LA + +S + D +K++DV
Sbjct: 168 LWDIETGQQTV-GFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 61.3 bits (142), Expect = 8e-09
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D ++ + L+D+++ F GH+G V D +S +
Sbjct: 145 YLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S+ LWD+ F H I A A P + +GS D T +L+D R+++ ++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFP-NGYAFTTGSDDATCRLFDLRADQELLM 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ +WD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 60.1 bits (139), Expect = 2e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G + + + H V +L LA + +S + D +K++DV
Sbjct: 168 LWDIETGQQTV-GFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 61.3 bits (142), Expect = 8e-09
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D ++ + L+D+++ F GH+G V D +S +
Sbjct: 145 YLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S+ LWD+ F H I A A P + +GS D T +L+D R+++ ++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFP-NGYAFTTGSDDATCRLFDLRADQELLM 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ +WD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 60.1 bits (139), Expect = 2e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G + + + H V +L LA + +S + D +K++DV
Sbjct: 168 LWDIETGQQTV-GFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 61.3 bits (142), Expect = 8e-09
Identities = 46/184 (25%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 603 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGHTNSANHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1021 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1080
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1081 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1139
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1140 LCFSPDGKMLISAGG-YIKWWNVVTG 1164
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 925 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 984
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 985 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1041
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1042 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1100
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1101 TGDDNGEIRIWNVSNGELLH 1120
Score = 36.7 bits (81), Expect = 0.20
Identities = 40/191 (20%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
ADG R++VA + + L++ S++ + GH VH F+ D ++ SDD+++ L
Sbjct: 808 ADGARIMVAAKNK--IFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 865
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSP 212
W+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 866 WE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLTE 918
Query: 213 VESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+S
Sbjct: 919 AQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLIS 977
Query: 270 ASLDRHVKIYD 280
+S D +++++
Sbjct: 978 SSDDAEIQVWN 988
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYD 696
>AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide binding
protein beta 2 protein.
Length = 340
Score = 61.3 bits (142), Expect = 8e-09
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D ++ + L+D+++ F GH+G V D +S +
Sbjct: 145 YLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S+ LWD+ F H I A A P + +GS D T +L+D R+++ ++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFP-NGYAFTTGSDDATCRLFDLRADQELLM 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ +WD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 60.1 bits (139), Expect = 2e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G + + + H V +L LA + +S + D +K++DV
Sbjct: 168 LWDIETGQQTV-GFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 61.3 bits (142), Expect = 8e-09
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D ++ + L+D+++ F GH+G V D +S +
Sbjct: 145 YLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S+ LWD+ F H I A A P + +GS D T +L+D R+++ ++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFP-NGYAFTTGSDDATCRLFDLRADQELLM 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ +WD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
Score = 60.1 bits (139), Expect = 2e-08
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A +P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP- 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G + + + H V +L LA + +S + D +K++DV
Sbjct: 168 LWDIETGQQTV-GFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>BC126114-1|AAI26115.1| 579|Homo sapiens cell division cycle 40
homolog (S. cerevisiae) protein.
Length = 579
Score = 60.9 bits (141), Expect = 1e-08
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQS-KNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F G LL++ + +KL++V + LR F GH+ V F + +S + D+ +
Sbjct: 297 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYL 356
Query: 151 GLWDISTEERIANF-NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN- 208
LWD T + I+ F N Y ++ ++G D + +D RS E + +
Sbjct: 357 KLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDR 416
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKV--WDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H V + +F+ F+S + ++V WDI K ++ S H T L+ N
Sbjct: 417 HLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT--LSPNGK 474
Query: 266 RLMSASLDRHVKIY 279
L S+D + I+
Sbjct: 475 WLACQSMDNQILIF 488
Score = 48.0 bits (109), Expect = 8e-05
Identities = 59/269 (21%), Positives = 116/269 (43%), Gaps = 23/269 (8%)
Query: 28 IYWKKLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAA 87
+Y ++ L + A+ + F+ + +A ++++D T + IS+F
Sbjct: 318 VYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTET---GQCISRFTNRK 374
Query: 88 YGGC--FRADG---RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKII 142
C F D L VAG+ + + +D++S +++ + H G V+ F + + +
Sbjct: 375 VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFV 434
Query: 143 SYSDDKSVGL--WDISTE-ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC- 198
S SDDKS+ + WDI + + IA + H+ + A SP + + S D+ + ++
Sbjct: 435 STSDDKSLRVWEWDIPVDFKYIAEPSMHS--MPAVTLSP-NGKWLACQSMDNQILIFGAQ 491
Query: 199 ---RSNETIMTVNH--GSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHH 252
R N+ + H F P IS G ++ +WD + KL S H
Sbjct: 492 NRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWD-WKTTKLYSRFKAHD 550
Query: 253 KT-VTTLRLASNNSRLMSASLDRHVKIYD 280
K + + S++++ D +K++D
Sbjct: 551 KVCIGAVWHPHETSKVITCGWDGLIKLWD 579
Score = 41.1 bits (92), Expect = 0.009
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 217 LFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
LF SG + +S +IK+W+++ + L H K V + + ++ +SA+ DR+
Sbjct: 296 LFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRY 355
Query: 276 VKIYDVSTFKVVH---NIDFPNAILSMAISEHDDILTVGMMD 314
+K++D T + + N P + + ++ GM D
Sbjct: 356 LKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Score = 35.9 bits (79), Expect = 0.35
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT--VNHGSPVES 215
+++I ++ HT + A P+S ++LS S D +KL++ + + H V
Sbjct: 278 KKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRD 337
Query: 216 TLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL-D 273
F +G F+SA +K+WD G + ++ + L A + D
Sbjct: 338 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Query: 274 RHVKIYDVSTFKVVHNID 291
+ + +D+ + ++V D
Sbjct: 398 KKIVQWDIRSGEIVQEYD 415
>BC117145-1|AAI17146.1| 579|Homo sapiens cell division cycle 40
homolog (S. cerevisiae) protein.
Length = 579
Score = 60.9 bits (141), Expect = 1e-08
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQS-KNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F G LL++ + +KL++V + LR F GH+ V F + +S + D+ +
Sbjct: 297 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYL 356
Query: 151 GLWDISTEERIANF-NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN- 208
LWD T + I+ F N Y ++ ++G D + +D RS E + +
Sbjct: 357 KLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDR 416
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKV--WDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H V + +F+ F+S + ++V WDI K ++ S H T L+ N
Sbjct: 417 HLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT--LSPNGK 474
Query: 266 RLMSASLDRHVKIY 279
L S+D + I+
Sbjct: 475 WLACQSMDNQILIF 488
Score = 48.0 bits (109), Expect = 8e-05
Identities = 59/269 (21%), Positives = 116/269 (43%), Gaps = 23/269 (8%)
Query: 28 IYWKKLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAA 87
+Y ++ L + A+ + F+ + +A ++++D T + IS+F
Sbjct: 318 VYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTET---GQCISRFTNRK 374
Query: 88 YGGC--FRADG---RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKII 142
C F D L VAG+ + + +D++S +++ + H G V+ F + + +
Sbjct: 375 VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFV 434
Query: 143 SYSDDKSVGL--WDISTE-ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC- 198
S SDDKS+ + WDI + + IA + H+ + A SP + + S D+ + ++
Sbjct: 435 STSDDKSLRVWEWDIPVDFKYIAEPSMHS--MPAVTLSP-NGKWLACQSMDNQILIFGAQ 491
Query: 199 ---RSNETIMTVNH--GSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHH 252
R N+ + H F P IS G ++ +WD + KL S H
Sbjct: 492 NRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWD-WKTTKLYSRFKAHD 550
Query: 253 KT-VTTLRLASNNSRLMSASLDRHVKIYD 280
K + + S++++ D +K++D
Sbjct: 551 KVCIGAVWHPHETSKVITCGWDGLIKLWD 579
Score = 41.1 bits (92), Expect = 0.009
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 217 LFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
LF SG + +S +IK+W+++ + L H K V + + ++ +SA+ DR+
Sbjct: 296 LFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRY 355
Query: 276 VKIYDVSTFKVVH---NIDFPNAILSMAISEHDDILTVGMMD 314
+K++D T + + N P + + ++ GM D
Sbjct: 356 LKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Score = 35.9 bits (79), Expect = 0.35
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT--VNHGSPVES 215
+++I ++ HT + A P+S ++LS S D +KL++ + + H V
Sbjct: 278 KKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRD 337
Query: 216 TLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL-D 273
F +G F+SA +K+WD G + ++ + L A + D
Sbjct: 338 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Query: 274 RHVKIYDVSTFKVVHNID 291
+ + +D+ + ++V D
Sbjct: 398 KKIVQWDIRSGEIVQEYD 415
>BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS
box-containing 2 protein.
Length = 404
Score = 60.9 bits (141), Expect = 1e-08
Identities = 44/162 (27%), Positives = 81/162 (50%), Gaps = 8/162 (4%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFT-KDQLKIISYSDDKSVGLWDIS 156
+L G+ + +K+++VQ+ +L +GH V FT L ++S S DK++ +WD++
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
Query: 157 TE-ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVE 214
++I + H ++ + SP ++ S + + +V L+ RS I + H S V
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISP-DCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVV 243
Query: 215 STLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTV 255
S F P + ++A T + +WD + G +L S HH V
Sbjct: 244 SCDFSPDSALLVTASYDTNVIMWDPYTGERLR---SLHHTQV 282
Score = 48.8 bits (111), Expect = 5e-05
Identities = 32/141 (22%), Positives = 68/141 (48%), Gaps = 4/141 (2%)
Query: 146 DDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM 205
+D + +W++ T + N + H D +R + +P I++S S D T++++D + +
Sbjct: 131 NDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQI 190
Query: 206 TV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
V H V P + SA G + + +W + L+ + H +V + +
Sbjct: 191 QVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSM-RSYTLIRKLEGHQSSVVSCDFSP 249
Query: 263 NNSRLMSASLDRHVKIYDVST 283
+++ L++AS D +V ++D T
Sbjct: 250 DSALLVTASYDTNVIMWDPYT 270
Score = 38.7 bits (86), Expect = 0.050
Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 80 ISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQL 139
+S ++ Y D +L + E +V L+ ++S ++R GH V F+ D
Sbjct: 193 LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSA 252
Query: 140 KIISYSDDKSVGLWDISTEERIANFNEHT 168
+++ S D +V +WD T ER+ + + HT
Sbjct: 253 LLVTASYDTNVIMWDPYTGERLRSLH-HT 280
>AL671518-2|CAI13322.1| 579|Homo sapiens cell division cycle 40
homolog (S. cerevisiae) protein.
Length = 579
Score = 60.9 bits (141), Expect = 1e-08
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQS-KNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F G LL++ + +KL++V + LR F GH+ V F + +S + D+ +
Sbjct: 297 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYL 356
Query: 151 GLWDISTEERIANF-NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN- 208
LWD T + I+ F N Y ++ ++G D + +D RS E + +
Sbjct: 357 KLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDR 416
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKV--WDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H V + +F+ F+S + ++V WDI K ++ S H T L+ N
Sbjct: 417 HLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT--LSPNGK 474
Query: 266 RLMSASLDRHVKIY 279
L S+D + I+
Sbjct: 475 WLACQSMDNQILIF 488
Score = 48.0 bits (109), Expect = 8e-05
Identities = 59/269 (21%), Positives = 116/269 (43%), Gaps = 23/269 (8%)
Query: 28 IYWKKLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAA 87
+Y ++ L + A+ + F+ + +A ++++D T + IS+F
Sbjct: 318 VYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTET---GQCISRFTNRK 374
Query: 88 YGGC--FRADG---RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKII 142
C F D L VAG+ + + +D++S +++ + H G V+ F + + +
Sbjct: 375 VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFV 434
Query: 143 SYSDDKSVGL--WDISTE-ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC- 198
S SDDKS+ + WDI + + IA + H+ + A SP + + S D+ + ++
Sbjct: 435 STSDDKSLRVWEWDIPVDFKYIAEPSMHS--MPAVTLSP-NGKWLACQSMDNQILIFGAQ 491
Query: 199 ---RSNETIMTVNH--GSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHH 252
R N+ + H F P IS G ++ +WD + KL S H
Sbjct: 492 NRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWD-WKTTKLYSRFKAHD 550
Query: 253 KT-VTTLRLASNNSRLMSASLDRHVKIYD 280
K + + S++++ D +K++D
Sbjct: 551 KVCIGAVWHPHETSKVITCGWDGLIKLWD 579
Score = 41.1 bits (92), Expect = 0.009
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 217 LFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
LF SG + +S +IK+W+++ + L H K V + + ++ +SA+ DR+
Sbjct: 296 LFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRY 355
Query: 276 VKIYDVSTFKVVH---NIDFPNAILSMAISEHDDILTVGMMD 314
+K++D T + + N P + + ++ GM D
Sbjct: 356 LKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Score = 35.9 bits (79), Expect = 0.35
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT--VNHGSPVES 215
+++I ++ HT + A P+S ++LS S D +KL++ + + H V
Sbjct: 278 KKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRD 337
Query: 216 TLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL-D 273
F +G F+SA +K+WD G + ++ + L A + D
Sbjct: 338 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Query: 274 RHVKIYDVSTFKVVHNID 291
+ + +D+ + ++V D
Sbjct: 398 KKIVQWDIRSGEIVQEYD 415
>AL671518-1|CAI13321.1| 539|Homo sapiens cell division cycle 40
homolog (S. cerevisiae) protein.
Length = 539
Score = 60.9 bits (141), Expect = 1e-08
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQS-KNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F G LL++ + +KL++V + LR F GH+ V F + +S + D+ +
Sbjct: 297 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYL 356
Query: 151 GLWDISTEERIANF-NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN- 208
LWD T + I+ F N Y ++ ++G D + +D RS E + +
Sbjct: 357 KLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDR 416
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKV--WDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H V + +F+ F+S + ++V WDI K ++ S H T L+ N
Sbjct: 417 HLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT--LSPNGK 474
Query: 266 RLMSASLDRHVKIY 279
L S+D + I+
Sbjct: 475 WLACQSMDNQILIF 488
Score = 44.8 bits (101), Expect = 8e-04
Identities = 30/132 (22%), Positives = 62/132 (46%), Gaps = 8/132 (6%)
Query: 28 IYWKKLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAA 87
+Y ++ L + A+ + F+ + +A ++++D T + IS+F
Sbjct: 318 VYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTET---GQCISRFTNRK 374
Query: 88 YGGC--FRADG---RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKII 142
C F D L VAG+ + + +D++S +++ + H G V+ F + + +
Sbjct: 375 VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFV 434
Query: 143 SYSDDKSVGLWD 154
S SDDKS+ +W+
Sbjct: 435 STSDDKSLRVWE 446
Score = 41.1 bits (92), Expect = 0.009
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 217 LFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
LF SG + +S +IK+W+++ + L H K V + + ++ +SA+ DR+
Sbjct: 296 LFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRY 355
Query: 276 VKIYDVSTFKVVH---NIDFPNAILSMAISEHDDILTVGMMD 314
+K++D T + + N P + + ++ GM D
Sbjct: 356 LKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Score = 35.9 bits (79), Expect = 0.35
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT--VNHGSPVES 215
+++I ++ HT + A P+S ++LS S D +KL++ + + H V
Sbjct: 278 KKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRD 337
Query: 216 TLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL-D 273
F +G F+SA +K+WD G + ++ + L A + D
Sbjct: 338 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Query: 274 RHVKIYDVSTFKVVHNID 291
+ + +D+ + ++V D
Sbjct: 398 KKIVQWDIRSGEIVQEYD 415
>AL445068-1|CAI22519.1| 539|Homo sapiens cell division cycle 40
homolog (S. cerevisiae) protein.
Length = 539
Score = 60.9 bits (141), Expect = 1e-08
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQS-KNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F G LL++ + +KL++V + LR F GH+ V F + +S + D+ +
Sbjct: 297 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYL 356
Query: 151 GLWDISTEERIANF-NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN- 208
LWD T + I+ F N Y ++ ++G D + +D RS E + +
Sbjct: 357 KLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDR 416
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKV--WDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H V + +F+ F+S + ++V WDI K ++ S H T L+ N
Sbjct: 417 HLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT--LSPNGK 474
Query: 266 RLMSASLDRHVKIY 279
L S+D + I+
Sbjct: 475 WLACQSMDNQILIF 488
Score = 44.8 bits (101), Expect = 8e-04
Identities = 30/132 (22%), Positives = 62/132 (46%), Gaps = 8/132 (6%)
Query: 28 IYWKKLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAA 87
+Y ++ L + A+ + F+ + +A ++++D T + IS+F
Sbjct: 318 VYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTET---GQCISRFTNRK 374
Query: 88 YGGC--FRADG---RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKII 142
C F D L VAG+ + + +D++S +++ + H G V+ F + + +
Sbjct: 375 VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFV 434
Query: 143 SYSDDKSVGLWD 154
S SDDKS+ +W+
Sbjct: 435 STSDDKSLRVWE 446
Score = 41.1 bits (92), Expect = 0.009
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 217 LFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
LF SG + +S +IK+W+++ + L H K V + + ++ +SA+ DR+
Sbjct: 296 LFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRY 355
Query: 276 VKIYDVSTFKVVH---NIDFPNAILSMAISEHDDILTVGMMD 314
+K++D T + + N P + + ++ GM D
Sbjct: 356 LKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Score = 35.9 bits (79), Expect = 0.35
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT--VNHGSPVES 215
+++I ++ HT + A P+S ++LS S D +KL++ + + H V
Sbjct: 278 KKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRD 337
Query: 216 TLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL-D 273
F +G F+SA +K+WD G + ++ + L A + D
Sbjct: 338 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Query: 274 RHVKIYDVSTFKVVHNID 291
+ + +D+ + ++V D
Sbjct: 398 KKIVQWDIRSGEIVQEYD 415
>AK222721-1|BAD96441.1| 579|Homo sapiens pre-mRNA splicing factor
17 variant protein.
Length = 579
Score = 60.9 bits (141), Expect = 1e-08
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQS-KNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F G LL++ + +KL++V + LR F GH+ V F + +S + D+ +
Sbjct: 297 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSEAVRDICFNTAGTQFLSAAYDRYL 356
Query: 151 GLWDISTEERIANF-NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN- 208
LWD T + I+ F N Y ++ ++G D + +D RS E + +
Sbjct: 357 KLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDR 416
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKV--WDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H V + +F+ F+S + ++V WDI K ++ S H T L+ N
Sbjct: 417 HLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT--LSPNGK 474
Query: 266 RLMSASLDRHVKIY 279
L S+D + I+
Sbjct: 475 WLACQSMDNQILIF 488
Score = 48.0 bits (109), Expect = 8e-05
Identities = 59/269 (21%), Positives = 116/269 (43%), Gaps = 23/269 (8%)
Query: 28 IYWKKLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAA 87
+Y ++ L + A+ + F+ + +A ++++D T + IS+F
Sbjct: 318 VYGERRCLRTFIGHSEAVRDICFNTAGTQFLSAAYDRYLKLWDTET---GQCISRFTNRK 374
Query: 88 YGGC--FRADG---RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKII 142
C F D L VAG+ + + +D++S +++ + H G V+ F + + +
Sbjct: 375 VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFV 434
Query: 143 SYSDDKSVGL--WDISTE-ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC- 198
S SDDKS+ + WDI + + IA + H+ + A SP + + S D+ + ++
Sbjct: 435 STSDDKSLRVWEWDIPVDFKYIAEPSMHS--MPAVTLSP-NGKWLACQSMDNQILIFGAQ 491
Query: 199 ---RSNETIMTVNH--GSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHH 252
R N+ + H F P IS G ++ +WD + KL S H
Sbjct: 492 NRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWD-WKTTKLYSRFKAHD 550
Query: 253 KT-VTTLRLASNNSRLMSASLDRHVKIYD 280
K + + S++++ D +K++D
Sbjct: 551 KVCIGAVWHPHETSKVITCGWDGLIKLWD 579
Score = 39.5 bits (88), Expect = 0.029
Identities = 23/102 (22%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 217 LFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
LF SG + +S +IK+W+++ + L H + V + + ++ +SA+ DR+
Sbjct: 296 LFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSEAVRDICFNTAGTQFLSAAYDRY 355
Query: 276 VKIYDVSTFKVVH---NIDFPNAILSMAISEHDDILTVGMMD 314
+K++D T + + N P + + ++ GM D
Sbjct: 356 LKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Score = 35.9 bits (79), Expect = 0.35
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT--VNHGSPVES 215
+++I ++ HT + A P+S ++LS S D +KL++ + + H V
Sbjct: 278 KKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSEAVRD 337
Query: 216 TLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL-D 273
F +G F+SA +K+WD G + ++ + L A + D
Sbjct: 338 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Query: 274 RHVKIYDVSTFKVVHNID 291
+ + +D+ + ++V D
Sbjct: 398 KKIVQWDIRSGEIVQEYD 415
>AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease
activating factor-1 protein.
Length = 1171
Score = 60.9 bits (141), Expect = 1e-08
Identities = 47/184 (25%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 611 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 670
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 671 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 730
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGG--IFISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ H + V F P SA GT +K+WD + + S
Sbjct: 731 CFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKPLASCSADGT-LKLWDATSANERKSI 789
Query: 247 NISQ 250
N+ Q
Sbjct: 790 NVKQ 793
Score = 41.9 bits (94), Expect = 0.005
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 14/202 (6%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 933 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 992
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 993 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1049
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKL-----LS--NISQHHKTVTTLRLA 261
V S F S + K+W++ NG L LS + H VT L +
Sbjct: 1050 QGTVLSCDISHDATKFSSTSADKTAKIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFS 1109
Query: 262 SNNSRLMSASLDRHVKIYDVST 283
+ L+SA ++K ++V T
Sbjct: 1110 PDGKMLISAG--GYIKWWNVVT 1129
Score = 36.7 bits (81), Expect = 0.20
Identities = 40/191 (20%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
ADG R++VA + + L++ S++ + GH VH F+ D ++ SDD+++ L
Sbjct: 816 ADGARIMVAAKNK--IFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 873
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSP 212
W+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 874 WE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLTE 926
Query: 213 VESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+S
Sbjct: 927 AQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLIS 985
Query: 270 ASLDRHVKIYD 280
+S D +++++
Sbjct: 986 SSDDAEIQVWN 996
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 622 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 680
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 681 ATCSVDKKVKIWNSMTGELVHTYD 704
>AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD
protein protein.
Length = 404
Score = 60.9 bits (141), Expect = 1e-08
Identities = 44/162 (27%), Positives = 81/162 (50%), Gaps = 8/162 (4%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFT-KDQLKIISYSDDKSVGLWDIS 156
+L G+ + +K+++VQ+ +L +GH V FT L ++S S DK++ +WD++
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
Query: 157 TE-ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVE 214
++I + H ++ + SP ++ S + + +V L+ RS I + H S V
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISP-DCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVV 243
Query: 215 STLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTV 255
S F P + ++A T + +WD + G +L S HH V
Sbjct: 244 SCDFSPDSALLVTASYDTNVIMWDPYTGERLR---SLHHTQV 282
Score = 48.8 bits (111), Expect = 5e-05
Identities = 32/141 (22%), Positives = 68/141 (48%), Gaps = 4/141 (2%)
Query: 146 DDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM 205
+D + +W++ T + N + H D +R + +P I++S S D T++++D + +
Sbjct: 131 NDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQI 190
Query: 206 TV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
V H V P + SA G + + +W + L+ + H +V + +
Sbjct: 191 QVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSM-RSYTLIRKLEGHQSSVVSCDFSP 249
Query: 263 NNSRLMSASLDRHVKIYDVST 283
+++ L++AS D +V ++D T
Sbjct: 250 DSALLVTASYDTNVIMWDPYT 270
Score = 38.7 bits (86), Expect = 0.050
Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 80 ISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQL 139
+S ++ Y D +L + E +V L+ ++S ++R GH V F+ D
Sbjct: 193 LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSA 252
Query: 140 KIISYSDDKSVGLWDISTEERIANFNEHT 168
+++ S D +V +WD T ER+ + + HT
Sbjct: 253 LLVTASYDTNVIMWDPYTGERLRSLH-HT 280
>AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein.
Length = 404
Score = 60.9 bits (141), Expect = 1e-08
Identities = 44/162 (27%), Positives = 81/162 (50%), Gaps = 8/162 (4%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFT-KDQLKIISYSDDKSVGLWDIS 156
+L G+ + +K+++VQ+ +L +GH V FT L ++S S DK++ +WD++
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
Query: 157 TE-ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVE 214
++I + H ++ + SP ++ S + + +V L+ RS I + H S V
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISP-DCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVV 243
Query: 215 STLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTV 255
S F P + ++A T + +WD + G +L S HH V
Sbjct: 244 SCDFSPDSALLVTASYDTNVIMWDPYTGERLR---SLHHTQV 282
Score = 48.8 bits (111), Expect = 5e-05
Identities = 32/141 (22%), Positives = 68/141 (48%), Gaps = 4/141 (2%)
Query: 146 DDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM 205
+D + +W++ T + N + H D +R + +P I++S S D T++++D + +
Sbjct: 131 NDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQI 190
Query: 206 TV--NHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
V H V P + SA G + + +W + L+ + H +V + +
Sbjct: 191 QVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSM-RSYTLIRKLEGHQSSVVSCDFSP 249
Query: 263 NNSRLMSASLDRHVKIYDVST 283
+++ L++AS D +V ++D T
Sbjct: 250 DSALLVTASYDTNVIMWDPYT 270
Score = 38.7 bits (86), Expect = 0.050
Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 80 ISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQL 139
+S ++ Y D +L + E +V L+ ++S ++R GH V F+ D
Sbjct: 193 LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSA 252
Query: 140 KIISYSDDKSVGLWDISTEERIANFNEHT 168
+++ S D +V +WD T ER+ + + HT
Sbjct: 253 LLVTASYDTNVIMWDPYTGERLRSLH-HT 280
>AF061241-1|AAC25166.1| 542|Homo sapiens splicing factor hPRP17
protein.
Length = 542
Score = 60.9 bits (141), Expect = 1e-08
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQS-KNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F G LL++ + +KL++V + LR F GH+ V F + +S + D+ +
Sbjct: 260 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYL 319
Query: 151 GLWDISTEERIANF-NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN- 208
LWD T + I+ F N Y ++ ++G D + +D RS E + +
Sbjct: 320 KLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDR 379
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKV--WDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H V + +F+ F+S + ++V WDI K ++ S H T L+ N
Sbjct: 380 HLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT--LSPNGK 437
Query: 266 RLMSASLDRHVKIY 279
L S+D + I+
Sbjct: 438 WLACQSMDNQILIF 451
Score = 48.0 bits (109), Expect = 8e-05
Identities = 59/269 (21%), Positives = 116/269 (43%), Gaps = 23/269 (8%)
Query: 28 IYWKKLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAA 87
+Y ++ L + A+ + F+ + +A ++++D T + IS+F
Sbjct: 281 VYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTET---GQCISRFTNRK 337
Query: 88 YGGC--FRADG---RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKII 142
C F D L VAG+ + + +D++S +++ + H G V+ F + + +
Sbjct: 338 VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFV 397
Query: 143 SYSDDKSVGL--WDISTE-ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC- 198
S SDDKS+ + WDI + + IA + H+ + A SP + + S D+ + ++
Sbjct: 398 STSDDKSLRVWEWDIPVDFKYIAEPSMHS--MPAVTLSP-NGKWLACQSMDNQILIFGAQ 454
Query: 199 ---RSNETIMTVNH--GSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHH 252
R N+ + H F P IS G ++ +WD + KL S H
Sbjct: 455 NRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWD-WKTTKLYSRFKAHD 513
Query: 253 KT-VTTLRLASNNSRLMSASLDRHVKIYD 280
K + + S++++ D +K++D
Sbjct: 514 KVCIGAVWHPHETSKVITCGWDGLIKLWD 542
Score = 41.1 bits (92), Expect = 0.009
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 217 LFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
LF SG + +S +IK+W+++ + L H K V + + ++ +SA+ DR+
Sbjct: 259 LFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRY 318
Query: 276 VKIYDVSTFKVVH---NIDFPNAILSMAISEHDDILTVGMMD 314
+K++D T + + N P + + ++ GM D
Sbjct: 319 LKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 360
Score = 35.9 bits (79), Expect = 0.35
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT--VNHGSPVES 215
+++I ++ HT + A P+S ++LS S D +KL++ + + H V
Sbjct: 241 KKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRD 300
Query: 216 TLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL-D 273
F +G F+SA +K+WD G + ++ + L A + D
Sbjct: 301 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 360
Query: 274 RHVKIYDVSTFKVVHNID 291
+ + +D+ + ++V D
Sbjct: 361 KKIVQWDIRSGEIVQEYD 378
>AF038392-1|AAC39730.1| 579|Homo sapiens pre-mRNA splicing factor
protein.
Length = 579
Score = 60.9 bits (141), Expect = 1e-08
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQS-KNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F G LL++ + +KL++V + LR F GH+ V F + +S + D+ +
Sbjct: 297 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYL 356
Query: 151 GLWDISTEERIANF-NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN- 208
LWD T + I+ F N Y ++ ++G D + +D RS E + +
Sbjct: 357 KLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDR 416
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKV--WDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H V + +F+ F+S + ++V WDI K ++ S H T L+ N
Sbjct: 417 HLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT--LSPNGK 474
Query: 266 RLMSASLDRHVKIY 279
L S+D + I+
Sbjct: 475 WLACQSMDNQILIF 488
Score = 48.0 bits (109), Expect = 8e-05
Identities = 59/269 (21%), Positives = 116/269 (43%), Gaps = 23/269 (8%)
Query: 28 IYWKKLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAA 87
+Y ++ L + A+ + F+ + +A ++++D T + IS+F
Sbjct: 318 VYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTET---GQCISRFTNRK 374
Query: 88 YGGC--FRADG---RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKII 142
C F D L VAG+ + + +D++S +++ + H G V+ F + + +
Sbjct: 375 VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFV 434
Query: 143 SYSDDKSVGL--WDISTE-ERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC- 198
S SDDKS+ + WDI + + IA + H+ + A SP + + S D+ + ++
Sbjct: 435 STSDDKSLRVWEWDIPVDFKYIAEPSMHS--MPAVTLSP-NGKWLACQSMDNQILIFGAQ 491
Query: 199 ---RSNETIMTVNH--GSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHH 252
R N+ + H F P IS G ++ +WD + KL S H
Sbjct: 492 NRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWD-WKTTKLYSRFKAHD 550
Query: 253 KT-VTTLRLASNNSRLMSASLDRHVKIYD 280
K + + S++++ D +K++D
Sbjct: 551 KVCIGAVWHPHETSKVITCGWDGLIKLWD 579
Score = 41.1 bits (92), Expect = 0.009
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 217 LFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
LF SG + +S +IK+W+++ + L H K V + + ++ +SA+ DR+
Sbjct: 296 LFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRY 355
Query: 276 VKIYDVSTFKVVH---NIDFPNAILSMAISEHDDILTVGMMD 314
+K++D T + + N P + + ++ GM D
Sbjct: 356 LKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Score = 35.9 bits (79), Expect = 0.35
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT--VNHGSPVES 215
+++I ++ HT + A P+S ++LS S D +KL++ + + H V
Sbjct: 278 KKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRD 337
Query: 216 TLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL-D 273
F +G F+SA +K+WD G + ++ + L A + D
Sbjct: 338 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 397
Query: 274 RHVKIYDVSTFKVVHNID 291
+ + +D+ + ++V D
Sbjct: 398 KKIVQWDIRSGEIVQEYD 415
>AB208903-1|BAD92140.1| 501|Homo sapiens pre-mRNA splicing factor
17 variant protein.
Length = 501
Score = 60.9 bits (141), Expect = 1e-08
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQS-KNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
F G LL++ + +KL++V + LR F GH+ V F + +S + D+ +
Sbjct: 296 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYL 355
Query: 151 GLWDISTEERIANF-NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN- 208
LWD T + I+ F N Y ++ ++G D + +D RS E + +
Sbjct: 356 KLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDR 415
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKV--WDIFNGGKLLSNISQHHKTVTTLRLASNNS 265
H V + +F+ F+S + ++V WDI K ++ S H T L+ N
Sbjct: 416 HLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVT--LSPNGK 473
Query: 266 RLMSASLDRHVKIY 279
L S+D + I+
Sbjct: 474 WLACQSMDNQILIF 487
Score = 44.8 bits (101), Expect = 8e-04
Identities = 30/132 (22%), Positives = 62/132 (46%), Gaps = 8/132 (6%)
Query: 28 IYWKKLGLPVLVKEFGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAA 87
+Y ++ L + A+ + F+ + +A ++++D T + IS+F
Sbjct: 317 VYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTET---GQCISRFTNRK 373
Query: 88 YGGC--FRADG---RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKII 142
C F D L VAG+ + + +D++S +++ + H G V+ F + + +
Sbjct: 374 VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFV 433
Query: 143 SYSDDKSVGLWD 154
S SDDKS+ +W+
Sbjct: 434 STSDDKSLRVWE 445
Score = 41.1 bits (92), Expect = 0.009
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 217 LFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRH 275
LF SG + +S +IK+W+++ + L H K V + + ++ +SA+ DR+
Sbjct: 295 LFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRY 354
Query: 276 VKIYDVSTFKVVH---NIDFPNAILSMAISEHDDILTVGMMD 314
+K++D T + + N P + + ++ GM D
Sbjct: 355 LKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 396
Score = 35.9 bits (79), Expect = 0.35
Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT--VNHGSPVES 215
+++I ++ HT + A P+S ++LS S D +KL++ + + H V
Sbjct: 277 KKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRD 336
Query: 216 TLFLPSGGIFISAG-GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASL-D 273
F +G F+SA +K+WD G + ++ + L A + D
Sbjct: 337 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSD 396
Query: 274 RHVKIYDVSTFKVVHNID 291
+ + +D+ + ++V D
Sbjct: 397 KKIVQWDIRSGEIVQEYD 414
>X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein.
Length = 919
Score = 60.5 bits (140), Expect = 1e-08
Identities = 58/255 (22%), Positives = 109/255 (42%), Gaps = 16/255 (6%)
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
+++ QS++ + GH + ++ D I++ DD V +W+ + F EH+
Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 416
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFISA 228
+ G + ++++ S D TV+ +D T P + S + + + G +SA
Sbjct: 417 GV-TGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSA 475
Query: 229 GGT---EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV-STF 284
G EI VW + G+LL +S H ++ L S L SAS D+ V+++D+ ++
Sbjct: 476 GAQDSFEIFVWSM-QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSW 534
Query: 285 KVVHNIDFPNAILSMAISEHDDILTVGMMDGIISIRKREEPVRQSE---------KRKNL 335
+ + + L++ L V ++ I+ E V+ RK L
Sbjct: 535 RTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKEL 594
Query: 336 LKFIPDHTSQTKADT 350
K H ++ KA T
Sbjct: 595 DKITAKHAAKGKAFT 609
Score = 48.4 bits (110), Expect = 6e-05
Identities = 36/192 (18%), Positives = 83/192 (43%), Gaps = 4/192 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ DG+ +V G ++ VK+++ S FT H+ V FT +++ S D +V
Sbjct: 381 YSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVR 440
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYD-HTVKLYDCRSNETIMTVN-H 209
+D+ F + A S +I+ +G+ D + ++ ++ + ++ H
Sbjct: 441 AFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
P+ F P + SA + +++WD+F+ + ++ + + + + L
Sbjct: 501 EGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDAL-AVTFRPDGAELA 559
Query: 269 SASLDRHVKIYD 280
A+L+ + +D
Sbjct: 560 VATLNSQITFWD 571
Score = 45.2 bits (102), Expect = 6e-04
Identities = 43/200 (21%), Positives = 80/200 (40%), Gaps = 5/200 (2%)
Query: 42 FGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVA 101
F ++ L +SP Y +V+V++ ++ ++ G F A G ++V
Sbjct: 373 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT 432
Query: 102 GIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS--YSDDKSVGLWDISTEE 159
+ V+ FD+ R FT +I+S D + +W + T
Sbjct: 433 SSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGR 492
Query: 160 RIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLF 218
+ + H I +P+ ++ S S+D TV+L+D S T T+ S + F
Sbjct: 493 LLDVLSGHEGPISGLCFNPMK-SVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTF 551
Query: 219 LPSGG-IFISAGGTEIKVWD 237
P G + ++ ++I WD
Sbjct: 552 RPDGAELAVATLNSQITFWD 571
>U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan protein
2 protein.
Length = 919
Score = 60.5 bits (140), Expect = 1e-08
Identities = 58/255 (22%), Positives = 109/255 (42%), Gaps = 16/255 (6%)
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
+++ QS++ + GH + ++ D I++ DD V +W+ + F EH+
Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 416
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFISA 228
+ G + ++++ S D TV+ +D T P + S + + + G +SA
Sbjct: 417 GV-TGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSA 475
Query: 229 GGT---EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV-STF 284
G EI VW + G+LL +S H ++ L S L SAS D+ V+++D+ ++
Sbjct: 476 GAQDSFEIFVWSM-QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSW 534
Query: 285 KVVHNIDFPNAILSMAISEHDDILTVGMMDGIISIRKREEPVRQSE---------KRKNL 335
+ + + L++ L V ++ I+ E V+ RK L
Sbjct: 535 RTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKEL 594
Query: 336 LKFIPDHTSQTKADT 350
K H ++ KA T
Sbjct: 595 DKITAKHAAKGKAFT 609
Score = 48.4 bits (110), Expect = 6e-05
Identities = 36/192 (18%), Positives = 83/192 (43%), Gaps = 4/192 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ DG+ +V G ++ VK+++ S FT H+ V FT +++ S D +V
Sbjct: 381 YSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVR 440
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYD-HTVKLYDCRSNETIMTVN-H 209
+D+ F + A S +I+ +G+ D + ++ ++ + ++ H
Sbjct: 441 AFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
P+ F P + SA + +++WD+F+ + ++ + + + + L
Sbjct: 501 EGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDAL-AVTFRPDGAELA 559
Query: 269 SASLDRHVKIYD 280
A+L+ + +D
Sbjct: 560 VATLNSQITFWD 571
Score = 45.2 bits (102), Expect = 6e-04
Identities = 43/200 (21%), Positives = 80/200 (40%), Gaps = 5/200 (2%)
Query: 42 FGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVA 101
F ++ L +SP Y +V+V++ ++ ++ G F A G ++V
Sbjct: 373 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT 432
Query: 102 GIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS--YSDDKSVGLWDISTEE 159
+ V+ FD+ R FT +I+S D + +W + T
Sbjct: 433 SSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGR 492
Query: 160 RIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLF 218
+ + H I +P+ ++ S S+D TV+L+D S T T+ S + F
Sbjct: 493 LLDVLSGHEGPISGLCFNPMK-SVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTF 551
Query: 219 LPSGG-IFISAGGTEIKVWD 237
P G + ++ ++I WD
Sbjct: 552 RPDGAELAVATLNSQITFWD 571
>U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan protein
2 protein.
Length = 919
Score = 60.5 bits (140), Expect = 1e-08
Identities = 58/255 (22%), Positives = 109/255 (42%), Gaps = 16/255 (6%)
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
+++ QS++ + GH + ++ D I++ DD V +W+ + F EH+
Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 416
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFISA 228
+ G + ++++ S D TV+ +D T P + S + + + G +SA
Sbjct: 417 GV-TGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSA 475
Query: 229 GGT---EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV-STF 284
G EI VW + G+LL +S H ++ L S L SAS D+ V+++D+ ++
Sbjct: 476 GAQDSFEIFVWSM-QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSW 534
Query: 285 KVVHNIDFPNAILSMAISEHDDILTVGMMDGIISIRKREEPVRQSE---------KRKNL 335
+ + + L++ L V ++ I+ E V+ RK L
Sbjct: 535 RTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKEL 594
Query: 336 LKFIPDHTSQTKADT 350
K H ++ KA T
Sbjct: 595 DKITAKHAAKGKAFT 609
Score = 48.4 bits (110), Expect = 6e-05
Identities = 36/192 (18%), Positives = 83/192 (43%), Gaps = 4/192 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ DG+ +V G ++ VK+++ S FT H+ V FT +++ S D +V
Sbjct: 381 YSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVR 440
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYD-HTVKLYDCRSNETIMTVN-H 209
+D+ F + A S +I+ +G+ D + ++ ++ + ++ H
Sbjct: 441 AFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
P+ F P + SA + +++WD+F+ + ++ + + + + L
Sbjct: 501 EGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDAL-AVTFRPDGAELA 559
Query: 269 SASLDRHVKIYD 280
A+L+ + +D
Sbjct: 560 VATLNSQITFWD 571
Score = 45.2 bits (102), Expect = 6e-04
Identities = 43/200 (21%), Positives = 80/200 (40%), Gaps = 5/200 (2%)
Query: 42 FGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVA 101
F ++ L +SP Y +V+V++ ++ ++ G F A G ++V
Sbjct: 373 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT 432
Query: 102 GIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS--YSDDKSVGLWDISTEE 159
+ V+ FD+ R FT +I+S D + +W + T
Sbjct: 433 SSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGR 492
Query: 160 RIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLF 218
+ + H I +P+ ++ S S+D TV+L+D S T T+ S + F
Sbjct: 493 LLDVLSGHEGPISGLCFNPMK-SVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTF 551
Query: 219 LPSGG-IFISAGGTEIKVWD 237
P G + ++ ++I WD
Sbjct: 552 RPDGAELAVATLNSQITFWD 571
>U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein.
Length = 919
Score = 60.5 bits (140), Expect = 1e-08
Identities = 58/255 (22%), Positives = 109/255 (42%), Gaps = 16/255 (6%)
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
+++ QS++ + GH + ++ D I++ DD V +W+ + F EH+
Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 416
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFISA 228
+ G + ++++ S D TV+ +D T P + S + + + G +SA
Sbjct: 417 GV-TGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSA 475
Query: 229 GGT---EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV-STF 284
G EI VW + G+LL +S H ++ L S L SAS D+ V+++D+ ++
Sbjct: 476 GAQDSFEIFVWSM-QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSW 534
Query: 285 KVVHNIDFPNAILSMAISEHDDILTVGMMDGIISIRKREEPVRQSE---------KRKNL 335
+ + + L++ L V ++ I+ E V+ RK L
Sbjct: 535 RTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKEL 594
Query: 336 LKFIPDHTSQTKADT 350
K H ++ KA T
Sbjct: 595 DKITAKHAAKGKAFT 609
Score = 48.4 bits (110), Expect = 6e-05
Identities = 36/192 (18%), Positives = 83/192 (43%), Gaps = 4/192 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ DG+ +V G ++ VK+++ S FT H+ V FT +++ S D +V
Sbjct: 381 YSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVR 440
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYD-HTVKLYDCRSNETIMTVN-H 209
+D+ F + A S +I+ +G+ D + ++ ++ + ++ H
Sbjct: 441 AFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
P+ F P + SA + +++WD+F+ + ++ + + + + L
Sbjct: 501 EGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDAL-AVTFRPDGAELA 559
Query: 269 SASLDRHVKIYD 280
A+L+ + +D
Sbjct: 560 VATLNSQITFWD 571
Score = 45.2 bits (102), Expect = 6e-04
Identities = 43/200 (21%), Positives = 80/200 (40%), Gaps = 5/200 (2%)
Query: 42 FGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVA 101
F ++ L +SP Y +V+V++ ++ ++ G F A G ++V
Sbjct: 373 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT 432
Query: 102 GIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS--YSDDKSVGLWDISTEE 159
+ V+ FD+ R FT +I+S D + +W + T
Sbjct: 433 SSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGR 492
Query: 160 RIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLF 218
+ + H I +P+ ++ S S+D TV+L+D S T T+ S + F
Sbjct: 493 LLDVLSGHEGPISGLCFNPMK-SVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTF 551
Query: 219 LPSGG-IFISAGGTEIKVWD 237
P G + ++ ++I WD
Sbjct: 552 RPDGAELAVATLNSQITFWD 571
>AP001753-1|BAA95553.1| 919|Homo sapiens periodic tryptophan
protein 2 homolog protein.
Length = 919
Score = 60.5 bits (140), Expect = 1e-08
Identities = 58/255 (22%), Positives = 109/255 (42%), Gaps = 16/255 (6%)
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
+++ QS++ + GH + ++ D I++ DD V +W+ + F EH+
Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 416
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFISA 228
+ G + ++++ S D TV+ +D T P + S + + + G +SA
Sbjct: 417 GV-TGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSA 475
Query: 229 GGT---EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV-STF 284
G EI VW + G+LL +S H ++ L S L SAS D+ V+++D+ ++
Sbjct: 476 GAQDSFEIFVWSM-QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSW 534
Query: 285 KVVHNIDFPNAILSMAISEHDDILTVGMMDGIISIRKREEPVRQSE---------KRKNL 335
+ + + L++ L V ++ I+ E V+ RK L
Sbjct: 535 RTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKEL 594
Query: 336 LKFIPDHTSQTKADT 350
K H ++ KA T
Sbjct: 595 DKITAKHAAKGKAFT 609
Score = 48.4 bits (110), Expect = 6e-05
Identities = 36/192 (18%), Positives = 83/192 (43%), Gaps = 4/192 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ DG+ +V G ++ VK+++ S FT H+ V FT +++ S D +V
Sbjct: 381 YSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVR 440
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYD-HTVKLYDCRSNETIMTVN-H 209
+D+ F + A S +I+ +G+ D + ++ ++ + ++ H
Sbjct: 441 AFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
P+ F P + SA + +++WD+F+ + ++ + + + + L
Sbjct: 501 EGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDAL-AVTFRPDGAELA 559
Query: 269 SASLDRHVKIYD 280
A+L+ + +D
Sbjct: 560 VATLNSQITFWD 571
Score = 45.2 bits (102), Expect = 6e-04
Identities = 43/200 (21%), Positives = 80/200 (40%), Gaps = 5/200 (2%)
Query: 42 FGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVA 101
F ++ L +SP Y +V+V++ ++ ++ G F A G ++V
Sbjct: 373 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT 432
Query: 102 GIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS--YSDDKSVGLWDISTEE 159
+ V+ FD+ R FT +I+S D + +W + T
Sbjct: 433 SSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGR 492
Query: 160 RIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLF 218
+ + H I +P+ ++ S S+D TV+L+D S T T+ S + F
Sbjct: 493 LLDVLSGHEGPISGLCFNPMK-SVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTF 551
Query: 219 LPSGG-IFISAGGTEIKVWD 237
P G + ++ ++I WD
Sbjct: 552 RPDGAELAVATLNSQITFWD 571
>AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta
subunit-like protein protein.
Length = 305
Score = 60.5 bits (140), Expect = 1e-08
Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F D +LLV ++ +K++DVQ N+ +GH V F D +S S DKSV
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVK 257
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC 198
+ D+ T + F +H D + + I+ G D + +YDC
Sbjct: 258 VRDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGD-DQEIHIYDC 303
Score = 56.8 bits (131), Expect = 2e-07
Identities = 40/192 (20%), Positives = 79/192 (41%), Gaps = 3/192 (1%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L FSP Y T +V ++ + ++ + + DG+ L +G +
Sbjct: 112 LAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGI 171
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
+ +F + + +L GH P+ F+ D +++ SDD + ++D+ + H
Sbjct: 172 INIFAIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGH 231
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGGIFI 226
++ A P + S S D +VK+ D + + T +H V + +G +
Sbjct: 232 ASWVLNVAFCPDDTHFV-SSSSDKSVKVRDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIV 290
Query: 227 SAG-GTEIKVWD 237
S G EI ++D
Sbjct: 291 SVGDDQEIHIYD 302
Score = 52.4 bits (120), Expect = 4e-06
Identities = 37/186 (19%), Positives = 85/186 (45%), Gaps = 4/186 (2%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+A ++L D+++ ++ F+ D + + + V ++ + + ++ +
Sbjct: 85 DAHIRLRDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSL 144
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGG 223
+ +I + A SP + SG+ D + ++ + + + T+ H P+ S F P
Sbjct: 145 DTRGKFILSIAYSP-DGKYLASGAIDGIINIFAIATGKLLHTLEGHAMPIRSLTFSPDSQ 203
Query: 224 IFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVS 282
+ ++A IK++D+ + L +S H V + +++ +S+S D+ VK+ DV
Sbjct: 204 LLVTASDDGYIKIYDVQHAN-LAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVRDVG 262
Query: 283 TFKVVH 288
T VH
Sbjct: 263 TRTCVH 268
Score = 39.5 bits (88), Expect = 0.029
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 7/182 (3%)
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S S D + L D+ ++I + + A SP S + +G++ V ++ S +
Sbjct: 81 SSSLDAHIRLRDLENGKQIKSIDAGPVDAWTLAFSPDS-QYLATGTHVGKVNIFGVESGK 139
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLR 259
+++ G + S + P G ++++G + I ++ I G KLL + H + +L
Sbjct: 140 KEYSLDTRGKFILSIAYSPDGK-YLASGAIDGIINIFAIATG-KLLHTLEGHAMPIRSLT 197
Query: 260 LASNNSRLMSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILTVGMMDGIIS 318
+ ++ L++AS D ++KIYDV + + + +L++A D D +
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVK 257
Query: 319 IR 320
+R
Sbjct: 258 VR 259
>AB001517-2|BAA21137.1| 919|Homo sapiens PWP2 protein protein.
Length = 919
Score = 60.5 bits (140), Expect = 1e-08
Identities = 58/255 (22%), Positives = 109/255 (42%), Gaps = 16/255 (6%)
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
+++ QS++ + GH + ++ D I++ DD V +W+ + F EH+
Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 416
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFISA 228
+ G + ++++ S D TV+ +D T P + S + + + G +SA
Sbjct: 417 GV-TGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSA 475
Query: 229 GGT---EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV-STF 284
G EI VW + G+LL +S H ++ L S L SAS D+ V+++D+ ++
Sbjct: 476 GAQDSFEIFVWSM-QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSW 534
Query: 285 KVVHNIDFPNAILSMAISEHDDILTVGMMDGIISIRKREEPVRQSE---------KRKNL 335
+ + + L++ L V ++ I+ E V+ RK L
Sbjct: 535 RTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKEL 594
Query: 336 LKFIPDHTSQTKADT 350
K H ++ KA T
Sbjct: 595 DKITAKHAAKGKAFT 609
Score = 48.4 bits (110), Expect = 6e-05
Identities = 36/192 (18%), Positives = 83/192 (43%), Gaps = 4/192 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ DG+ +V G ++ VK+++ S FT H+ V FT +++ S D +V
Sbjct: 381 YSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVR 440
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYD-HTVKLYDCRSNETIMTVN-H 209
+D+ F + A S +I+ +G+ D + ++ ++ + ++ H
Sbjct: 441 AFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 500
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
P+ F P + SA + +++WD+F+ + ++ + + + + L
Sbjct: 501 EGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDAL-AVTFRPDGAELA 559
Query: 269 SASLDRHVKIYD 280
A+L+ + +D
Sbjct: 560 VATLNSQITFWD 571
Score = 45.2 bits (102), Expect = 6e-04
Identities = 43/200 (21%), Positives = 80/200 (40%), Gaps = 5/200 (2%)
Query: 42 FGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVA 101
F ++ L +SP Y +V+V++ ++ ++ G F A G ++V
Sbjct: 373 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT 432
Query: 102 GIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS--YSDDKSVGLWDISTEE 159
+ V+ FD+ R FT +I+S D + +W + T
Sbjct: 433 SSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGR 492
Query: 160 RIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC-RSNETIMTVNHGSPVESTLF 218
+ + H I +P+ ++ S S+D TV+L+D S T T+ S + F
Sbjct: 493 LLDVLSGHEGPISGLCFNPMK-SVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTF 551
Query: 219 LPSGG-IFISAGGTEIKVWD 237
P G + ++ ++I WD
Sbjct: 552 RPDGAELAVATLNSQITFWD 571
>U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein.
Length = 1224
Score = 60.1 bits (139), Expect = 2e-08
Identities = 34/150 (22%), Positives = 69/150 (46%), Gaps = 1/150 (0%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L F P P+ + + +Q++D + + G F L V+G ++
Sbjct: 15 LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYK 74
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
+K+++ + + L GH + TFF + I+S SDD+++ +W+ + + H
Sbjct: 75 IKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGH 134
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYD 197
Y+ P + D+++S S D TV+++D
Sbjct: 135 NHYVMCAQFHP-TEDLVVSASLDQTVRVWD 163
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Query: 150 VGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+ LWD I F+EH +R P + +SG D+ +K+++ + + T+
Sbjct: 33 IQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQP-LFVSGGDDYKIKVWNYKLRRCLFTLLG 91
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H + +T F +SA + I+VW+ + + ++ H+ V + +
Sbjct: 92 HLDYIRTTFFHHEYPWILSASDDQTIRVWN-WQSRTCVCVLTGHNHYVMCAQFHPTEDLV 150
Query: 268 MSASLDRHVKIYDVS 282
+SASLD+ V+++D+S
Sbjct: 151 VSASLDQTVRVWDIS 165
Score = 42.7 bits (96), Expect = 0.003
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 7/159 (4%)
Query: 24 THDIIYWKKLGLPVLVKEFGAIDYLDFSP--VEPYYFAATCSVRVQVYDPVTKVVAKNIS 81
T D++ L V V + + + SP VE T D V K V +
Sbjct: 146 TEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHD 205
Query: 82 KFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFT--GHTGPVHRTFFTKDQL 139
+ V A F L+V+G ++ VK++ + V T GH V F Q
Sbjct: 206 RGVNWA---AFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQE 262
Query: 140 KIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
I+S S+DKS+ +WD+S + F D AA P
Sbjct: 263 LILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHP 301
Score = 40.3 bits (90), Expect = 0.016
Identities = 46/243 (18%), Positives = 102/243 (41%), Gaps = 18/243 (7%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + +DF +P + + +++V++ + + ++ F + +++
Sbjct: 52 GPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSA 111
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIA 162
++ +++++ QS+ + V TGH V F + ++S S D++V +WDIS +
Sbjct: 112 SDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDIS---GLR 168
Query: 163 NFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSG 222
N + + D L G+ D VK + H V F P+
Sbjct: 169 KKNLSPGAVESDVRGITGVD--LFGTTDAVVK---------HVLEGHDRGVNWAAFHPTM 217
Query: 223 GIFIS-AGGTEIKVWDIFNGGKL--LSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
+ +S A ++K+W + N K + H+ V+ ++S S D+ ++++
Sbjct: 218 PLIVSGADDRQVKIWRM-NESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVW 276
Query: 280 DVS 282
D+S
Sbjct: 277 DMS 279
>BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein.
Length = 1233
Score = 60.1 bits (139), Expect = 2e-08
Identities = 34/150 (22%), Positives = 69/150 (46%), Gaps = 1/150 (0%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L F P P+ + + +Q++D + + G F L V+G ++
Sbjct: 15 LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYK 74
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
+K+++ + + L GH + TFF + I+S SDD+++ +W+ + + H
Sbjct: 75 IKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGH 134
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYD 197
Y+ P + D+++S S D TV+++D
Sbjct: 135 NHYVMCAQFHP-TEDLVVSASLDQTVRVWD 163
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Query: 150 VGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+ LWD I F+EH +R P + +SG D+ +K+++ + + T+
Sbjct: 33 IQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQP-LFVSGGDDYKIKVWNYKLRRCLFTLLG 91
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H + +T F +SA + I+VW+ + + ++ H+ V + +
Sbjct: 92 HLDYIRTTFFHHEYPWILSASDDQTIRVWN-WQSRTCVCVLTGHNHYVMCAQFHPTEDLV 150
Query: 268 MSASLDRHVKIYDVS 282
+SASLD+ V+++D+S
Sbjct: 151 VSASLDQTVRVWDIS 165
Score = 42.7 bits (96), Expect = 0.003
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 7/159 (4%)
Query: 24 THDIIYWKKLGLPVLVKEFGAIDYLDFSP--VEPYYFAATCSVRVQVYDPVTKVVAKNIS 81
T D++ L V V + + + SP VE T D V K V +
Sbjct: 146 TEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHD 205
Query: 82 KFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFT--GHTGPVHRTFFTKDQL 139
+ V A F L+V+G ++ VK++ + V T GH V F Q
Sbjct: 206 RGVNWA---AFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQE 262
Query: 140 KIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
I+S S+DKS+ +WD+S + F D AA P
Sbjct: 263 LILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHP 301
Score = 40.3 bits (90), Expect = 0.016
Identities = 46/243 (18%), Positives = 102/243 (41%), Gaps = 18/243 (7%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + +DF +P + + +++V++ + + ++ F + +++
Sbjct: 52 GPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSA 111
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIA 162
++ +++++ QS+ + V TGH V F + ++S S D++V +WDIS +
Sbjct: 112 SDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDIS---GLR 168
Query: 163 NFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSG 222
N + + D L G+ D VK + H V F P+
Sbjct: 169 KKNLSPGAVESDVRGITGVD--LFGTTDAVVK---------HVLEGHDRGVNWAAFHPTM 217
Query: 223 GIFIS-AGGTEIKVWDIFNGGKL--LSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
+ +S A ++K+W + N K + H+ V+ ++S S D+ ++++
Sbjct: 218 PLIVSGADDRQVKIWRM-NESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVW 276
Query: 280 DVS 282
D+S
Sbjct: 277 DMS 279
>AL513282-3|CAI12455.1| 1233|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1233
Score = 60.1 bits (139), Expect = 2e-08
Identities = 34/150 (22%), Positives = 69/150 (46%), Gaps = 1/150 (0%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L F P P+ + + +Q++D + + G F L V+G ++
Sbjct: 15 LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYK 74
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
+K+++ + + L GH + TFF + I+S SDD+++ +W+ + + H
Sbjct: 75 IKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGH 134
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYD 197
Y+ P + D+++S S D TV+++D
Sbjct: 135 NHYVMCAQFHP-TEDLVVSASLDQTVRVWD 163
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Query: 150 VGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+ LWD I F+EH +R P + +SG D+ +K+++ + + T+
Sbjct: 33 IQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQP-LFVSGGDDYKIKVWNYKLRRCLFTLLG 91
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H + +T F +SA + I+VW+ + + ++ H+ V + +
Sbjct: 92 HLDYIRTTFFHHEYPWILSASDDQTIRVWN-WQSRTCVCVLTGHNHYVMCAQFHPTEDLV 150
Query: 268 MSASLDRHVKIYDVS 282
+SASLD+ V+++D+S
Sbjct: 151 VSASLDQTVRVWDIS 165
Score = 42.7 bits (96), Expect = 0.003
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 7/159 (4%)
Query: 24 THDIIYWKKLGLPVLVKEFGAIDYLDFSP--VEPYYFAATCSVRVQVYDPVTKVVAKNIS 81
T D++ L V V + + + SP VE T D V K V +
Sbjct: 146 TEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHD 205
Query: 82 KFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFT--GHTGPVHRTFFTKDQL 139
+ V A F L+V+G ++ VK++ + V T GH V F Q
Sbjct: 206 RGVNWA---AFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQE 262
Query: 140 KIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
I+S S+DKS+ +WD+S + F D AA P
Sbjct: 263 LILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHP 301
Score = 40.3 bits (90), Expect = 0.016
Identities = 46/243 (18%), Positives = 102/243 (41%), Gaps = 18/243 (7%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + +DF +P + + +++V++ + + ++ F + +++
Sbjct: 52 GPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSA 111
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIA 162
++ +++++ QS+ + V TGH V F + ++S S D++V +WDIS +
Sbjct: 112 SDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDIS---GLR 168
Query: 163 NFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSG 222
N + + D L G+ D VK + H V F P+
Sbjct: 169 KKNLSPGAVESDVRGITGVD--LFGTTDAVVK---------HVLEGHDRGVNWAAFHPTM 217
Query: 223 GIFIS-AGGTEIKVWDIFNGGKL--LSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
+ +S A ++K+W + N K + H+ V+ ++S S D+ ++++
Sbjct: 218 PLIVSGADDRQVKIWRM-NESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVW 276
Query: 280 DVS 282
D+S
Sbjct: 277 DMS 279
>AL513282-2|CAI12454.1| 1224|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1224
Score = 60.1 bits (139), Expect = 2e-08
Identities = 34/150 (22%), Positives = 69/150 (46%), Gaps = 1/150 (0%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L F P P+ + + +Q++D + + G F L V+G ++
Sbjct: 15 LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYK 74
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
+K+++ + + L GH + TFF + I+S SDD+++ +W+ + + H
Sbjct: 75 IKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGH 134
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYD 197
Y+ P + D+++S S D TV+++D
Sbjct: 135 NHYVMCAQFHP-TEDLVVSASLDQTVRVWD 163
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Query: 150 VGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+ LWD I F+EH +R P + +SG D+ +K+++ + + T+
Sbjct: 33 IQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQP-LFVSGGDDYKIKVWNYKLRRCLFTLLG 91
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H + +T F +SA + I+VW+ + + ++ H+ V + +
Sbjct: 92 HLDYIRTTFFHHEYPWILSASDDQTIRVWN-WQSRTCVCVLTGHNHYVMCAQFHPTEDLV 150
Query: 268 MSASLDRHVKIYDVS 282
+SASLD+ V+++D+S
Sbjct: 151 VSASLDQTVRVWDIS 165
Score = 42.7 bits (96), Expect = 0.003
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 7/159 (4%)
Query: 24 THDIIYWKKLGLPVLVKEFGAIDYLDFSP--VEPYYFAATCSVRVQVYDPVTKVVAKNIS 81
T D++ L V V + + + SP VE T D V K V +
Sbjct: 146 TEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHD 205
Query: 82 KFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFT--GHTGPVHRTFFTKDQL 139
+ V A F L+V+G ++ VK++ + V T GH V F Q
Sbjct: 206 RGVNWA---AFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQE 262
Query: 140 KIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
I+S S+DKS+ +WD+S + F D AA P
Sbjct: 263 LILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHP 301
Score = 40.3 bits (90), Expect = 0.016
Identities = 46/243 (18%), Positives = 102/243 (41%), Gaps = 18/243 (7%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + +DF +P + + +++V++ + + ++ F + +++
Sbjct: 52 GPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSA 111
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIA 162
++ +++++ QS+ + V TGH V F + ++S S D++V +WDIS +
Sbjct: 112 SDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDIS---GLR 168
Query: 163 NFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSG 222
N + + D L G+ D VK + H V F P+
Sbjct: 169 KKNLSPGAVESDVRGITGVD--LFGTTDAVVK---------HVLEGHDRGVNWAAFHPTM 217
Query: 223 GIFIS-AGGTEIKVWDIFNGGKL--LSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
+ +S A ++K+W + N K + H+ V+ ++S S D+ ++++
Sbjct: 218 PLIVSGADDRQVKIWRM-NESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVW 276
Query: 280 DVS 282
D+S
Sbjct: 277 DMS 279
>AL445230-2|CAI15005.1| 1224|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1224
Score = 60.1 bits (139), Expect = 2e-08
Identities = 34/150 (22%), Positives = 69/150 (46%), Gaps = 1/150 (0%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L F P P+ + + +Q++D + + G F L V+G ++
Sbjct: 15 LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYK 74
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
+K+++ + + L GH + TFF + I+S SDD+++ +W+ + + H
Sbjct: 75 IKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGH 134
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYD 197
Y+ P + D+++S S D TV+++D
Sbjct: 135 NHYVMCAQFHP-TEDLVVSASLDQTVRVWD 163
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Query: 150 VGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+ LWD I F+EH +R P + +SG D+ +K+++ + + T+
Sbjct: 33 IQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQP-LFVSGGDDYKIKVWNYKLRRCLFTLLG 91
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H + +T F +SA + I+VW+ + + ++ H+ V + +
Sbjct: 92 HLDYIRTTFFHHEYPWILSASDDQTIRVWN-WQSRTCVCVLTGHNHYVMCAQFHPTEDLV 150
Query: 268 MSASLDRHVKIYDVS 282
+SASLD+ V+++D+S
Sbjct: 151 VSASLDQTVRVWDIS 165
Score = 42.7 bits (96), Expect = 0.003
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 7/159 (4%)
Query: 24 THDIIYWKKLGLPVLVKEFGAIDYLDFSP--VEPYYFAATCSVRVQVYDPVTKVVAKNIS 81
T D++ L V V + + + SP VE T D V K V +
Sbjct: 146 TEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHD 205
Query: 82 KFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFT--GHTGPVHRTFFTKDQL 139
+ V A F L+V+G ++ VK++ + V T GH V F Q
Sbjct: 206 RGVNWA---AFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQE 262
Query: 140 KIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
I+S S+DKS+ +WD+S + F D AA P
Sbjct: 263 LILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHP 301
Score = 40.3 bits (90), Expect = 0.016
Identities = 46/243 (18%), Positives = 102/243 (41%), Gaps = 18/243 (7%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + +DF +P + + +++V++ + + ++ F + +++
Sbjct: 52 GPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSA 111
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIA 162
++ +++++ QS+ + V TGH V F + ++S S D++V +WDIS +
Sbjct: 112 SDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDIS---GLR 168
Query: 163 NFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSG 222
N + + D L G+ D VK + H V F P+
Sbjct: 169 KKNLSPGAVESDVRGITGVD--LFGTTDAVVK---------HVLEGHDRGVNWAAFHPTM 217
Query: 223 GIFIS-AGGTEIKVWDIFNGGKL--LSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
+ +S A ++K+W + N K + H+ V+ ++S S D+ ++++
Sbjct: 218 PLIVSGADDRQVKIWRM-NESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVW 276
Query: 280 DVS 282
D+S
Sbjct: 277 DMS 279
>AL445230-1|CAI15004.1| 1233|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1233
Score = 60.1 bits (139), Expect = 2e-08
Identities = 34/150 (22%), Positives = 69/150 (46%), Gaps = 1/150 (0%)
Query: 48 LDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAA 107
L F P P+ + + +Q++D + + G F L V+G ++
Sbjct: 15 LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYK 74
Query: 108 VKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEH 167
+K+++ + + L GH + TFF + I+S SDD+++ +W+ + + H
Sbjct: 75 IKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGH 134
Query: 168 TDYIRAGAASPISPDIILSGSYDHTVKLYD 197
Y+ P + D+++S S D TV+++D
Sbjct: 135 NHYVMCAQFHP-TEDLVVSASLDQTVRVWD 163
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Query: 150 VGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-N 208
+ LWD I F+EH +R P + +SG D+ +K+++ + + T+
Sbjct: 33 IQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQP-LFVSGGDDYKIKVWNYKLRRCLFTLLG 91
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H + +T F +SA + I+VW+ + + ++ H+ V + +
Sbjct: 92 HLDYIRTTFFHHEYPWILSASDDQTIRVWN-WQSRTCVCVLTGHNHYVMCAQFHPTEDLV 150
Query: 268 MSASLDRHVKIYDVS 282
+SASLD+ V+++D+S
Sbjct: 151 VSASLDQTVRVWDIS 165
Score = 42.7 bits (96), Expect = 0.003
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 7/159 (4%)
Query: 24 THDIIYWKKLGLPVLVKEFGAIDYLDFSP--VEPYYFAATCSVRVQVYDPVTKVVAKNIS 81
T D++ L V V + + + SP VE T D V K V +
Sbjct: 146 TEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHD 205
Query: 82 KFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFT--GHTGPVHRTFFTKDQL 139
+ V A F L+V+G ++ VK++ + V T GH V F Q
Sbjct: 206 RGVNWA---AFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQE 262
Query: 140 KIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
I+S S+DKS+ +WD+S + F D AA P
Sbjct: 263 LILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHP 301
Score = 40.3 bits (90), Expect = 0.016
Identities = 46/243 (18%), Positives = 102/243 (41%), Gaps = 18/243 (7%)
Query: 43 GAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAG 102
G + +DF +P + + +++V++ + + ++ F + +++
Sbjct: 52 GPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSA 111
Query: 103 IEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIA 162
++ +++++ QS+ + V TGH V F + ++S S D++V +WDIS +
Sbjct: 112 SDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDIS---GLR 168
Query: 163 NFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSG 222
N + + D L G+ D VK + H V F P+
Sbjct: 169 KKNLSPGAVESDVRGITGVD--LFGTTDAVVK---------HVLEGHDRGVNWAAFHPTM 217
Query: 223 GIFIS-AGGTEIKVWDIFNGGKL--LSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
+ +S A ++K+W + N K + H+ V+ ++S S D+ ++++
Sbjct: 218 PLIVSGADDRQVKIWRM-NESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVW 276
Query: 280 DVS 282
D+S
Sbjct: 277 DMS 279
>AB209438-1|BAD92675.1| 316|Homo sapiens PWP2 periodic tryptophan
protein homolog protein.
Length = 316
Score = 60.1 bits (139), Expect = 2e-08
Identities = 44/176 (25%), Positives = 82/176 (46%), Gaps = 6/176 (3%)
Query: 110 LFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTD 169
+++ QS++ + GH + ++ D I++ DD V +W+ + F EH+
Sbjct: 77 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 136
Query: 170 YIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVE-STLFLPSGGIFISA 228
+ G + ++++ S D TV+ +D T P + S + + + G +SA
Sbjct: 137 GV-TGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSA 195
Query: 229 GGT---EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
G EI VW + G+LL +S H ++ L S L SAS D+ V+++D+
Sbjct: 196 GAQDSFEIFVWSM-QTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDM 250
Score = 46.8 bits (106), Expect = 2e-04
Identities = 32/152 (21%), Positives = 68/152 (44%), Gaps = 3/152 (1%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ DG+ +V G ++ VK+++ S FT H+ V FT +++ S D +V
Sbjct: 101 YSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVR 160
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYD-HTVKLYDCRSNETIMTVN-H 209
+D+ F + A S +I+ +G+ D + ++ ++ + ++ H
Sbjct: 161 AFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGH 220
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFN 240
P+ F P + SA + +++WD+F+
Sbjct: 221 EGPISGLCFNPMKSVLASASWDKTVRLWDMFD 252
Score = 41.5 bits (93), Expect = 0.007
Identities = 37/175 (21%), Positives = 70/175 (40%), Gaps = 7/175 (4%)
Query: 42 FGAIDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVA 101
F ++ L +SP Y +V+V++ ++ ++ G F A G ++V
Sbjct: 93 FNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVT 152
Query: 102 GIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS--YSDDKSVGLWDISTEE 159
+ V+ FD+ R FT +I+S D + +W + T
Sbjct: 153 SSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGR 212
Query: 160 RIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC----RSNETIMTVNHG 210
+ + H I +P+ ++ S S+D TV+L+D R+ ET+ + G
Sbjct: 213 LLDVLSGHEGPISGLCFNPMK-SVLASASWDKTVRLWDMFDSWRTKETLALTSDG 266
Score = 34.3 bits (75), Expect = 1.1
Identities = 20/109 (18%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 209 HGSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H + + + + P G ++ G ++KVW+ +G ++ ++H VT + + +
Sbjct: 92 HFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVT-FTEHSSGVTGVTFTATGYVV 150
Query: 268 MSASLDRHVKIYDVSTFKVVHNIDF--PNAILSMAISEHDDILTVGMMD 314
+++S+D V+ +D+ ++ P +A+ +I++ G D
Sbjct: 151 VTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQD 199
>BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1
(Drosophila) protein.
Length = 485
Score = 59.7 bits (138), Expect = 3e-08
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 4/141 (2%)
Query: 99 LVAGIEEAAVKLFD-VQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
LV+G ++ + L+ + K L TGH +++ F+ D + S S DKS+ LWD T
Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 403
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVEST 216
+ +A+ H + A S S +++SGS D T+K++D ++ + M + H V +
Sbjct: 404 GKYLASLRGHVAAVYQIAWSADS-RLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAV 462
Query: 217 LFLPSGGIFISAGGTE-IKVW 236
+ P G S G + +++W
Sbjct: 463 DWSPDGQRVASGGKDKCLRIW 483
Score = 51.2 bits (117), Expect = 9e-06
Identities = 28/109 (25%), Positives = 56/109 (51%)
Query: 45 IDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIE 104
I+ + FSP +A+ ++++D T ++ V A Y + AD RLLV+G
Sbjct: 375 INQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSS 434
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
++ +K++DV+++ + GH V+ ++ D ++ S DK + +W
Sbjct: 435 DSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 48.0 bits (109), Expect = 8e-05
Identities = 44/186 (23%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Query: 85 EAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISY 144
EA F G+ L +G + V+ +D+ ++ GH V ++ D K+ S
Sbjct: 115 EAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASG 174
Query: 145 SDDKSVGLWDISTEERIA-NFNEHTDYIRAGAASPI--SPD--IILSGSYDHTVKLYDCR 199
+ + LWD ST +++ H+ +I + P+ +P+ + S S D +V+++D
Sbjct: 175 CKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTT 234
Query: 200 SN--ETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTT 257
+ E I+T H V + G ++ ++ IKVW + G L + H V T
Sbjct: 235 AGRCERILT-GHTQSVTCLRWGGDGLLYSASQDRTIKVWRA-HDGVLCRTLQGHGHWVNT 292
Query: 258 LRLASN 263
+ L+++
Sbjct: 293 MALSTD 298
Score = 48.0 bits (109), Expect = 8e-05
Identities = 24/105 (22%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F D R++ + + ++KL+D ++ L GH V++ ++ D ++S S D ++
Sbjct: 380 FSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLK 439
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+WD+ ++ + H D + A SP + SG D ++++
Sbjct: 440 VWDVKAQKLAMDLPGHADEVYAVDWSP-DGQRVASGGKDKCLRIW 483
Score = 39.5 bits (88), Expect = 0.029
Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 11/164 (6%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GH+ V F+ + S S D +V WD+STE H ++ + + SP
Sbjct: 112 GHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKK- 170
Query: 184 ILSGSYDHTVKLYDCRSNETI--MTVNHGSPVESTLFLPSGG------IFISAGGTEIKV 235
+ SG + + L+D + + + H + + P + S+ +++
Sbjct: 171 LASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRI 230
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
WD G+ ++ H ++VT LR + L SAS DR +K++
Sbjct: 231 WDT-TAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDRTIKVW 272
>BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein.
Length = 484
Score = 59.7 bits (138), Expect = 3e-08
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 4/141 (2%)
Query: 99 LVAGIEEAAVKLFD-VQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
LV+G ++ + L+ + K L TGH +++ F+ D + S S DKS+ LWD T
Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 402
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVEST 216
+ +A+ H + A S S +++SGS D T+K++D ++ + M + H V +
Sbjct: 403 GKYLASLRGHVAAVYQIAWSADS-RLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAV 461
Query: 217 LFLPSGGIFISAGGTE-IKVW 236
+ P G S G + +++W
Sbjct: 462 DWSPDGQRVASGGKDKCLRIW 482
Score = 51.2 bits (117), Expect = 9e-06
Identities = 28/109 (25%), Positives = 56/109 (51%)
Query: 45 IDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIE 104
I+ + FSP +A+ ++++D T ++ V A Y + AD RLLV+G
Sbjct: 374 INQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSS 433
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
++ +K++DV+++ + GH V+ ++ D ++ S DK + +W
Sbjct: 434 DSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482
Score = 48.0 bits (109), Expect = 8e-05
Identities = 44/186 (23%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Query: 85 EAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISY 144
EA F G+ L +G + V+ +D+ ++ GH V ++ D K+ S
Sbjct: 114 EAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASG 173
Query: 145 SDDKSVGLWDISTEERIA-NFNEHTDYIRAGAASPI--SPD--IILSGSYDHTVKLYDCR 199
+ + LWD ST +++ H+ +I + P+ +P+ + S S D +V+++D
Sbjct: 174 CKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTT 233
Query: 200 SN--ETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTT 257
+ E I+T H V + G ++ ++ IKVW + G L + H V T
Sbjct: 234 AGRCERILT-GHTQSVTCLRWGGDGLLYSASQDRTIKVWRA-HDGVLCRTLQGHGHWVNT 291
Query: 258 LRLASN 263
+ L+++
Sbjct: 292 MALSTD 297
Score = 48.0 bits (109), Expect = 8e-05
Identities = 24/105 (22%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F D R++ + + ++KL+D ++ L GH V++ ++ D ++S S D ++
Sbjct: 379 FSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLK 438
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+WD+ ++ + H D + A SP + SG D ++++
Sbjct: 439 VWDVKAQKLAMDLPGHADEVYAVDWSP-DGQRVASGGKDKCLRIW 482
Score = 39.5 bits (88), Expect = 0.029
Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 11/164 (6%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GH+ V F+ + S S D +V WD+STE H ++ + + SP
Sbjct: 111 GHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKK- 169
Query: 184 ILSGSYDHTVKLYDCRSNETI--MTVNHGSPVESTLFLPSGG------IFISAGGTEIKV 235
+ SG + + L+D + + + H + + P + S+ +++
Sbjct: 170 LASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRI 229
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
WD G+ ++ H ++VT LR + L SAS DR +K++
Sbjct: 230 WDT-TAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDRTIKVW 271
>AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens
cDNA FLJ10458 fis, clone NT2RP1001457, highly similar to
Homo sapiens partial mRNA for beta-transducin family
protein. ).
Length = 485
Score = 59.7 bits (138), Expect = 3e-08
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 4/141 (2%)
Query: 99 LVAGIEEAAVKLFD-VQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
LV+G ++ + L+ + K L TGH +++ F+ D + S S DKS+ LWD T
Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 403
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVEST 216
+ +A+ H + A S S +++SGS D T+K++D ++ + M + H V +
Sbjct: 404 GKYLASLRGHVAAVYQIAWSADS-RLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAV 462
Query: 217 LFLPSGGIFISAGGTE-IKVW 236
+ P G S G + +++W
Sbjct: 463 DWSPDGQRVASGGKDKCLRIW 483
Score = 51.2 bits (117), Expect = 9e-06
Identities = 28/109 (25%), Positives = 56/109 (51%)
Query: 45 IDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIE 104
I+ + FSP +A+ ++++D T ++ V A Y + AD RLLV+G
Sbjct: 375 INQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSS 434
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
++ +K++DV+++ + GH V+ ++ D ++ S DK + +W
Sbjct: 435 DSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 48.0 bits (109), Expect = 8e-05
Identities = 44/186 (23%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Query: 85 EAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISY 144
EA F G+ L +G + V+ +D+ ++ GH V ++ D K+ S
Sbjct: 115 EAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASG 174
Query: 145 SDDKSVGLWDISTEERIA-NFNEHTDYIRAGAASPI--SPD--IILSGSYDHTVKLYDCR 199
+ + LWD ST +++ H+ +I + P+ +P+ + S S D +V+++D
Sbjct: 175 CKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTT 234
Query: 200 SN--ETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTT 257
+ E I+T H V + G ++ ++ IKVW + G L + H V T
Sbjct: 235 AGRCERILT-GHTQSVTCLRWGGDGLLYSASQDRTIKVWRA-HDGVLCRTLQGHGHWVNT 292
Query: 258 LRLASN 263
+ L+++
Sbjct: 293 MALSTD 298
Score = 48.0 bits (109), Expect = 8e-05
Identities = 24/105 (22%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F D R++ + + ++KL+D ++ L GH V++ ++ D ++S S D ++
Sbjct: 380 FSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLK 439
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+WD+ ++ + H D + A SP + SG D ++++
Sbjct: 440 VWDVKAQKLAMDLPGHADEVYAVDWSP-DGQRVASGGKDKCLRIW 483
Score = 39.5 bits (88), Expect = 0.029
Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 11/164 (6%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GH+ V F+ + S S D +V WD+STE H ++ + + SP
Sbjct: 112 GHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKK- 170
Query: 184 ILSGSYDHTVKLYDCRSNETI--MTVNHGSPVESTLFLPSGG------IFISAGGTEIKV 235
+ SG + + L+D + + + H + + P + S+ +++
Sbjct: 171 LASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRI 230
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
WD G+ ++ H ++VT LR + L SAS DR +K++
Sbjct: 231 WDT-TAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDRTIKVW 272
>AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 59.7 bits (138), Expect = 3e-08
Identities = 46/184 (25%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 72 VTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHR 131
+T + + +A Y CF DG+ + + + +++F ++ L H V
Sbjct: 603 ITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLC 662
Query: 132 TFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIIL-SGSYD 190
F+ D I + S DK V +W+ T E + ++EH++ + + S ++L +GS D
Sbjct: 663 CAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSD 722
Query: 191 HTVKLYDCRSNETIMTV-NHGSPVESTLFLPSGGIF--ISAGGTEIKVWDIFNGGKLLS- 246
+KL+D E T+ + V F P + SA GT +K+WD + + S
Sbjct: 723 CFLKLWDLNQKECRNTMFGRTNSVNHCRFSPDDKLLASCSADGT-LKLWDATSANERKSI 781
Query: 247 NISQ 250
N+ Q
Sbjct: 782 NVKQ 785
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ VK++++ + N + F H G V + D K S S DK+ +W +
Sbjct: 1021 DGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHEL 1080
Query: 165 NEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIM---------TVNHGSPVES 215
H +R A S + ++ +G + +++++ + E + HG V
Sbjct: 1081 RGHNGCVRCSAFS-VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTD 1139
Query: 216 TLFLPSGGIFISAGGTEIKVWDIFNG 241
F P G + ISAGG IK W++ G
Sbjct: 1140 LCFSPDGKMLISAGG-YIKWWNVVTG 1164
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/200 (21%), Positives = 87/200 (43%), Gaps = 6/200 (3%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSV 150
C + + G E A+++ ++ + + + H V FT D+ +IS SDD +
Sbjct: 925 CLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 984
Query: 151 GLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYD-CRSNETIMTVNH 209
+W+ ++ I H + ++ + +LS S+D TVK+++ N+ V H
Sbjct: 985 QVWNWQLDKCIF-LRGHQETVKDFRL--LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCH 1041
Query: 210 GSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLM 268
V S F S + K+W F+ L + H+ V + +++ L
Sbjct: 1042 QGTVLSCDISHDATKFSSTSADKTAKIWS-FDLLLPLHELRGHNGCVRCSAFSVDSTLLA 1100
Query: 269 SASLDRHVKIYDVSTFKVVH 288
+ + ++I++VS +++H
Sbjct: 1101 TGDDNGEIRIWNVSNGELLH 1120
Score = 36.7 bits (81), Expect = 0.20
Identities = 40/191 (20%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
Query: 94 ADG-RLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGL 152
ADG R++VA + + L++ S++ + GH VH F+ D ++ SDD+++ L
Sbjct: 808 ADGARIMVAAKNK--IFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRL 865
Query: 153 WDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSP 212
W+ T++ N ++ + ++ + DH +L N +++ +
Sbjct: 866 WE--TKKVCKN---SAVMLKQEVDVVFQENEVMVLAVDHIRRLQ--LINGRTGQIDYLTE 918
Query: 213 VESTLFLPSGGIFISAGGTE---IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
+ + S + A G E I++ ++ N ++ + QH KTV ++ ++ L+S
Sbjct: 919 AQVSCCCLSPHLQYIAFGDENGAIEILELVN-NRIFQSRFQHKKTVWHIQFTADEKTLIS 977
Query: 270 ASLDRHVKIYD 280
+S D +++++
Sbjct: 978 SSDDAEIQVWN 988
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 209 HGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRL 267
H V F G S G + ++V+ G KLL I H V ++++ +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLE-IKAHEDEVLCCAFSTDDRFI 672
Query: 268 MSASLDRHVKIYDVSTFKVVHNID 291
+ S+D+ VKI++ T ++VH D
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYD 696
>AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog
variant protein.
Length = 487
Score = 59.7 bits (138), Expect = 3e-08
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 4/141 (2%)
Query: 99 LVAGIEEAAVKLFD-VQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
LV+G ++ + L+ + K L TGH +++ F+ D + S S DKS+ LWD T
Sbjct: 346 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 405
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVEST 216
+ +A+ H + A S S +++SGS D T+K++D ++ + M + H V +
Sbjct: 406 GKYLASLRGHVAAVYQIAWSADS-RLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAV 464
Query: 217 LFLPSGGIFISAGGTE-IKVW 236
+ P G S G + +++W
Sbjct: 465 DWSPDGQRVASGGKDKCLRIW 485
Score = 51.2 bits (117), Expect = 9e-06
Identities = 28/109 (25%), Positives = 56/109 (51%)
Query: 45 IDYLDFSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIE 104
I+ + FSP +A+ ++++D T ++ V A Y + AD RLLV+G
Sbjct: 377 INQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSS 436
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
++ +K++DV+++ + GH V+ ++ D ++ S DK + +W
Sbjct: 437 DSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 485
Score = 48.0 bits (109), Expect = 8e-05
Identities = 44/186 (23%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Query: 85 EAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISY 144
EA F G+ L +G + V+ +D+ ++ GH V ++ D K+ S
Sbjct: 117 EAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASG 176
Query: 145 SDDKSVGLWDISTEERIA-NFNEHTDYIRAGAASPI--SPD--IILSGSYDHTVKLYDCR 199
+ + LWD ST +++ H+ +I + P+ +P+ + S S D +V+++D
Sbjct: 177 CKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTT 236
Query: 200 SN--ETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTT 257
+ E I+T H V + G ++ ++ IKVW + G L + H V T
Sbjct: 237 AGRCERILT-GHTQSVTCLRWGGDGLLYSASQDRTIKVWRA-HDGVLCRTLQGHGHWVNT 294
Query: 258 LRLASN 263
+ L+++
Sbjct: 295 MALSTD 300
Score = 48.0 bits (109), Expect = 8e-05
Identities = 24/105 (22%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F D R++ + + ++KL+D ++ L GH V++ ++ D ++S S D ++
Sbjct: 382 FSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLK 441
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+WD+ ++ + H D + A SP + SG D ++++
Sbjct: 442 VWDVKAQKLAMDLPGHADEVYAVDWSP-DGQRVASGGKDKCLRIW 485
Score = 39.5 bits (88), Expect = 0.029
Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 11/164 (6%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GH+ V F+ + S S D +V WD+STE H ++ + + SP
Sbjct: 114 GHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKK- 172
Query: 184 ILSGSYDHTVKLYDCRSNETI--MTVNHGSPVESTLFLPSGG------IFISAGGTEIKV 235
+ SG + + L+D + + + H + + P + S+ +++
Sbjct: 173 LASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRI 232
Query: 236 WDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIY 279
WD G+ ++ H ++VT LR + L SAS DR +K++
Sbjct: 233 WDT-TAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDRTIKVW 274
>M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human
signal-transducing guanine nucleotide-binding regulatory
(G) protein beta subunit mRNA, complete cds. ).
Length = 340
Score = 59.3 bits (137), Expect = 3e-08
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPI 179
R GH ++ + D ++S S D + +WD T ++ + ++ A
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT-CAYAX 107
Query: 180 SPDIILSGSYDHTVKLYDCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIK 234
S + + G D+ +Y ++ E + V+ H + FL I S+G T
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCA 167
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WDI G + + + H V +L LA N +S + D +K++DV
Sbjct: 168 LWDIETGQQTV-GFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDV 213
Score = 59.3 bits (137), Expect = 3e-08
Identities = 45/198 (22%), Positives = 85/198 (42%), Gaps = 7/198 (3%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D ++ + L+D+++ F GH+G V + +S +
Sbjct: 145 YLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S+ LWD+ F H I A A P + +GS D T +L+D R+++ ++
Sbjct: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFP-NGYAFTTGSDDATCRLFDLRADQELLM 263
Query: 207 VNHGS---PVESTLFLPSGGIFISA-GGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS 262
+H + + S F SG + ++ +WD G + ++ H V+ L +
Sbjct: 264 YSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR-AGVLAGHDNRVSCLGVTD 322
Query: 263 NNSRLMSASLDRHVKIYD 280
+ + + S D +KI++
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
>AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa protein
protein.
Length = 521
Score = 59.3 bits (137), Expect = 3e-08
Identities = 56/242 (23%), Positives = 97/242 (40%), Gaps = 18/242 (7%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFF---------TKDQLKII 142
F + ++L KL+ V N+L GH V F KD + +
Sbjct: 238 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKD-VNLA 296
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S + D SV LW + ++E +A+ HT + P S + + YD + +L+D + E
Sbjct: 297 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQE 355
Query: 203 TIM-TVNHGSPVESTLFLPSGGIFISAGGTEI--KVWDIFNGGKLLSNISQHHKTVTTLR 259
I+ H V F G + GG + +VWD+ G+ + + H K + +
Sbjct: 356 EILHQEGHSMGVYDIAFHQDGSL-AGTGGLDAFGRVWDL-RTGRCIMFLEDHLKEIYGIN 413
Query: 260 LASNNSRLMSASLDRHVKIYDVSTFKVVHNI-DFPNAILSMAISE-HDDILTVGMMDGII 317
+ N + + S D K++D+ + V+ I N + + H + L G D
Sbjct: 414 FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPPHQNLVTGVKFEPIHGNFLLTGAYDNTA 473
Query: 318 SI 319
I
Sbjct: 474 KI 475
Score = 47.2 bits (107), Expect = 1e-04
Identities = 24/109 (22%), Positives = 50/109 (45%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F DG L G +A +++D+++ + H ++ F+ + I + S D
Sbjct: 368 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEDHLKEIYGINFSPNGYHIATGSGD 427
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+ +WD+ + H + + PI + +L+G+YD+T K++
Sbjct: 428 NTCKVWDLRQRRCVYTIPPHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476
>CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein.
Length = 521
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/242 (23%), Positives = 98/242 (40%), Gaps = 18/242 (7%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFF---------TKDQLKII 142
F + ++L KL+ V N+L GH V F KD + +
Sbjct: 238 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKD-VNLA 296
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S + D SV LW + ++E +A+ HT + P S + + YD + +L+D + E
Sbjct: 297 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQE 355
Query: 203 TIM-TVNHGSPVESTLFLPSGGIFISAGGTEI--KVWDIFNGGKLLSNISQHHKTVTTLR 259
I+ H V F G + GG + +VWD+ G+ + + H K + +
Sbjct: 356 EILHQEGHSMGVYDIAFHQDGSL-AGTGGLDAFGRVWDL-RTGRCIMFLEGHLKEIYGIN 413
Query: 260 LASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISE--HDDILTVGMMDGII 317
+ N + + S D K++D+ + V+ I +++ E H + L G D
Sbjct: 414 FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTA 473
Query: 318 SI 319
I
Sbjct: 474 KI 475
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/109 (22%), Positives = 51/109 (46%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F DG L G +A +++D+++ + GH ++ F+ + I + S D
Sbjct: 368 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 427
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+ +WD+ + H + + PI + +L+G+YD+T K++
Sbjct: 428 NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476
>BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/242 (23%), Positives = 98/242 (40%), Gaps = 18/242 (7%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFF---------TKDQLKII 142
F + ++L KL+ V N+L GH V F KD + +
Sbjct: 238 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKD-VNLA 296
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S + D SV LW + ++E +A+ HT + P S + + YD + +L+D + E
Sbjct: 297 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQE 355
Query: 203 TIM-TVNHGSPVESTLFLPSGGIFISAGGTEI--KVWDIFNGGKLLSNISQHHKTVTTLR 259
I+ H V F G + GG + +VWD+ G+ + + H K + +
Sbjct: 356 EILHQEGHSMGVYDIAFHQDGSL-AGTGGLDAFGRVWDL-RTGRCIMFLEGHLKEIYGIN 413
Query: 260 LASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISE--HDDILTVGMMDGII 317
+ N + + S D K++D+ + V+ I +++ E H + L G D
Sbjct: 414 FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTA 473
Query: 318 SI 319
I
Sbjct: 474 KI 475
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/109 (22%), Positives = 51/109 (46%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F DG L G +A +++D+++ + GH ++ F+ + I + S D
Sbjct: 368 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 427
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+ +WD+ + H + + PI + +L+G+YD+T K++
Sbjct: 428 NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476
>BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/242 (23%), Positives = 98/242 (40%), Gaps = 18/242 (7%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFF---------TKDQLKII 142
F + ++L KL+ V N+L GH V F KD + +
Sbjct: 239 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKD-VNLA 297
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S + D SV LW + ++E +A+ HT + P S + + YD + +L+D + E
Sbjct: 298 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQE 356
Query: 203 TIM-TVNHGSPVESTLFLPSGGIFISAGGTEI--KVWDIFNGGKLLSNISQHHKTVTTLR 259
I+ H V F G + GG + +VWD+ G+ + + H K + +
Sbjct: 357 EILHQEGHSMGVYDIAFHQDGSL-AGTGGLDAFGRVWDL-RTGRCIMFLEGHLKEIYGIN 414
Query: 260 LASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISE--HDDILTVGMMDGII 317
+ N + + S D K++D+ + V+ I +++ E H + L G D
Sbjct: 415 FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTA 474
Query: 318 SI 319
I
Sbjct: 475 KI 476
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/109 (22%), Positives = 51/109 (46%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F DG L G +A +++D+++ + GH ++ F+ + I + S D
Sbjct: 369 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 428
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+ +WD+ + H + + PI + +L+G+YD+T K++
Sbjct: 429 NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477
>AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6
snRNP-specific spliceosomal protein protein.
Length = 521
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/242 (23%), Positives = 98/242 (40%), Gaps = 18/242 (7%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFF---------TKDQLKII 142
F + ++L KL+ V N+L GH V F KD + +
Sbjct: 238 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKD-VNLA 296
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S + D SV LW + ++E +A+ HT + P S + + YD + +L+D + E
Sbjct: 297 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQE 355
Query: 203 TIM-TVNHGSPVESTLFLPSGGIFISAGGTEI--KVWDIFNGGKLLSNISQHHKTVTTLR 259
I+ H V F G + GG + +VWD+ G+ + + H K + +
Sbjct: 356 EILHQEGHSMGVYDIAFHQDGSL-AGTGGLDAFGRVWDL-RTGRCIMFLEGHLKEIYGIN 413
Query: 260 LASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISE--HDDILTVGMMDGII 317
+ N + + S D K++D+ + V+ I +++ E H + L G D
Sbjct: 414 FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTA 473
Query: 318 SI 319
I
Sbjct: 474 KI 475
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/109 (22%), Positives = 51/109 (46%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F DG L G +A +++D+++ + GH ++ F+ + I + S D
Sbjct: 368 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 427
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+ +WD+ + H + + PI + +L+G+YD+T K++
Sbjct: 428 NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476
>AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/242 (23%), Positives = 98/242 (40%), Gaps = 18/242 (7%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFF---------TKDQLKII 142
F + ++L KL+ V N+L GH V F KD + +
Sbjct: 238 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKD-VNLA 296
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S + D SV LW + ++E +A+ HT + P S + + YD + +L+D + E
Sbjct: 297 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQE 355
Query: 203 TIM-TVNHGSPVESTLFLPSGGIFISAGGTEI--KVWDIFNGGKLLSNISQHHKTVTTLR 259
I+ H V F G + GG + +VWD+ G+ + + H K + +
Sbjct: 356 EILHQEGHSMGVYDIAFHQDGSL-AGTGGLDAFGRVWDL-RTGRCIMFLEGHLKEIYGIN 413
Query: 260 LASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISE--HDDILTVGMMDGII 317
+ N + + S D K++D+ + V+ I +++ E H + L G D
Sbjct: 414 FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTA 473
Query: 318 SI 319
I
Sbjct: 474 KI 475
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/109 (22%), Positives = 51/109 (46%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F DG L G +A +++D+++ + GH ++ F+ + I + S D
Sbjct: 368 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 427
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+ +WD+ + H + + PI + +L+G+YD+T K++
Sbjct: 428 NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476
>AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/242 (23%), Positives = 98/242 (40%), Gaps = 18/242 (7%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFF---------TKDQLKII 142
F + ++L KL+ V N+L GH V F KD + +
Sbjct: 239 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKD-VNLA 297
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S + D SV LW + ++E +A+ HT + P S + + YD + +L+D + E
Sbjct: 298 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQE 356
Query: 203 TIM-TVNHGSPVESTLFLPSGGIFISAGGTEI--KVWDIFNGGKLLSNISQHHKTVTTLR 259
I+ H V F G + GG + +VWD+ G+ + + H K + +
Sbjct: 357 EILHQEGHSMGVYDIAFHQDGSL-AGTGGLDAFGRVWDL-RTGRCIMFLEGHLKEIYGIN 414
Query: 260 LASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISE--HDDILTVGMMDGII 317
+ N + + S D K++D+ + V+ I +++ E H + L G D
Sbjct: 415 FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTA 474
Query: 318 SI 319
I
Sbjct: 475 KI 476
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/109 (22%), Positives = 51/109 (46%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F DG L G +A +++D+++ + GH ++ F+ + I + S D
Sbjct: 369 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 428
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+ +WD+ + H + + PI + +L+G+YD+T K++
Sbjct: 429 NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477
>AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear
ribonucleoprotein hPrp4 protein.
Length = 522
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/242 (23%), Positives = 98/242 (40%), Gaps = 18/242 (7%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFF---------TKDQLKII 142
F + ++L KL+ V N+L GH V F KD + +
Sbjct: 239 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKD-VNLA 297
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S + D SV LW + ++E +A+ HT + P S + + YD + +L+D + E
Sbjct: 298 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQE 356
Query: 203 TIM-TVNHGSPVESTLFLPSGGIFISAGGTEI--KVWDIFNGGKLLSNISQHHKTVTTLR 259
I+ H V F G + GG + +VWD+ G+ + + H K + +
Sbjct: 357 EILHQEGHSMGVYDIAFHQDGSL-AGTGGLDAFGRVWDL-RTGRCIMFLEGHLKEIYGIN 414
Query: 260 LASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISE--HDDILTVGMMDGII 317
+ N + + S D K++D+ + V+ I +++ E H + L G D
Sbjct: 415 FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTA 474
Query: 318 SI 319
I
Sbjct: 475 KI 476
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/109 (22%), Positives = 51/109 (46%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F DG L G +A +++D+++ + GH ++ F+ + I + S D
Sbjct: 369 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 428
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+ +WD+ + H + + PI + +L+G+YD+T K++
Sbjct: 429 NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477
>AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant
protein.
Length = 537
Score = 58.4 bits (135), Expect = 6e-08
Identities = 56/242 (23%), Positives = 98/242 (40%), Gaps = 18/242 (7%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFF---------TKDQLKII 142
F + ++L KL+ V N+L GH V F KD + +
Sbjct: 254 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKD-VNLA 312
Query: 143 SYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
S + D SV LW + ++E +A+ HT + P S + + YD + +L+D + E
Sbjct: 313 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQE 371
Query: 203 TIM-TVNHGSPVESTLFLPSGGIFISAGGTEI--KVWDIFNGGKLLSNISQHHKTVTTLR 259
I+ H V F G + GG + +VWD+ G+ + + H K + +
Sbjct: 372 EILHQEGHSMGVYDIAFHQDGSL-AGTGGLDAFGRVWDL-RTGRCIMFLEGHLKEIYGIN 429
Query: 260 LASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISE--HDDILTVGMMDGII 317
+ N + + S D K++D+ + V+ I +++ E H + L G D
Sbjct: 430 FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTA 489
Query: 318 SI 319
I
Sbjct: 490 KI 491
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/109 (22%), Positives = 51/109 (46%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F DG L G +A +++D+++ + GH ++ F+ + I + S D
Sbjct: 384 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 443
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+ +WD+ + H + + PI + +L+G+YD+T K++
Sbjct: 444 NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 492
>U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p
protein.
Length = 520
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/241 (21%), Positives = 95/241 (39%), Gaps = 16/241 (6%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTG--------PVHRTFFTKDQLKIIS 143
F + ++L KL+ V N+L GH P + + S
Sbjct: 237 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTKKEQLHSIPKSTVSLDPKDVNLAS 296
Query: 144 YSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNET 203
+ D SV LW + ++E +A+ HT + P S + + YD + +L+D + E
Sbjct: 297 CAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQEE 355
Query: 204 IM-TVNHGSPVESTLFLPSGGIFISAGGTEI--KVWDIFNGGKLLSNISQHHKTVTTLRL 260
I+ H V F G + GG + +VWD+ G+ + + H K + +
Sbjct: 356 ILHQEGHSMGVYDIAFHQDGSL-AGTGGLDAFGRVWDL-RTGRCIMFLEGHLKEIYGINF 413
Query: 261 ASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISE--HDDILTVGMMDGIIS 318
+ N + + S D K++D+ + V+ I +++ E H + L G D
Sbjct: 414 SPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAK 473
Query: 319 I 319
I
Sbjct: 474 I 474
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/109 (22%), Positives = 51/109 (46%)
Query: 88 YGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDD 147
Y F DG L G +A +++D+++ + GH ++ F+ + I + S D
Sbjct: 367 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 426
Query: 148 KSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
+ +WD+ + H + + PI + +L+G+YD+T K++
Sbjct: 427 NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 475
>AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3
protein.
Length = 943
Score = 57.6 bits (133), Expect = 1e-07
Identities = 58/265 (21%), Positives = 115/265 (43%), Gaps = 19/265 (7%)
Query: 85 EAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISY 144
E A F R +V G + ++L+D+ S N+L H G + + DQ ++
Sbjct: 455 EYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTG 514
Query: 145 SDDKSVGLWDI-------STEERIANFNEHT----DYIRAGAASPISPDIILSGSYDHTV 193
DKSV WD ST++R++ T + + + SP + ++ D TV
Sbjct: 515 GADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSP-NQKLLAVSLLDCTV 573
Query: 194 KLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE--IKVWDIFNGGKLLSNISQ 250
K++ + + +++ H PV + + G I+ G + +K+W + + G ++
Sbjct: 574 KIFYVDTLKFFLSLYGHKLPV-ICMDISHDGALIATGSADRNVKIWGL-DFGDCHKSLFA 631
Query: 251 HHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILT 309
H +V L+ + +A D +K +D F+ + ++ I +A+S D +
Sbjct: 632 HDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVV 691
Query: 310 VGMMDGIISIRKR-EEPVRQSEKRK 333
D + + +R EP+ E+R+
Sbjct: 692 SSSHDKSLRLWERTREPLILEEERE 716
Score = 52.8 bits (121), Expect = 3e-06
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQL--KIISYSDDK 148
C DG L G E+ ++++F + S F GH + T DQL ++ S S D
Sbjct: 72 CPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAI--TTLKYDQLGGRLASGSKDT 129
Query: 149 SVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT-V 207
+ +WD+ E + H D I A +++++ D VK +D + T V
Sbjct: 130 DIIVWDVINESGLYRLKGHKDAI-TQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMV 188
Query: 208 NHGSPVESTLFLPSGGIFIS-AGGTEIKVWDI 238
H + V + L I+ A +E++VWDI
Sbjct: 189 GHRTEVWGLVLLSEEKRLITGASDSELRVWDI 220
Score = 37.1 bits (82), Expect = 0.15
Identities = 23/111 (20%), Positives = 50/111 (45%), Gaps = 1/111 (0%)
Query: 68 VYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTG 127
V+D + + + +A F + LLV ++ VK +D+ +++ + GH
Sbjct: 133 VWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRT 192
Query: 128 PVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
V ++ ++I+ + D + +WDI+ + I + E D + +SP
Sbjct: 193 EVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIED-PEEPDPKKIKGSSP 242
Score = 34.7 bits (76), Expect = 0.81
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 193 VKLYDCRSNETIMTVNHGSPVESTLFLPS-GGIFISAGGTE--IKVWDIFNG-GKLLSNI 248
V ++D R E I+ + G E T PS G+ ++ G + I+++ + +G G + N
Sbjct: 47 VFIWDLRKGEKILILQ-GLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFN- 104
Query: 249 SQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
H +TTL+ RL S S D + ++DV
Sbjct: 105 -GHKAAITTLKYDQLGGRLASGSKDTDIIVWDV 136
>AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3
protein.
Length = 943
Score = 57.6 bits (133), Expect = 1e-07
Identities = 58/265 (21%), Positives = 115/265 (43%), Gaps = 19/265 (7%)
Query: 85 EAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISY 144
E A F R +V G + ++L+D+ S N+L H G + + DQ ++
Sbjct: 455 EYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTG 514
Query: 145 SDDKSVGLWDI-------STEERIANFNEHT----DYIRAGAASPISPDIILSGSYDHTV 193
DKSV WD ST++R++ T + + + SP + ++ D TV
Sbjct: 515 GADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSP-NQKLLAVSLLDCTV 573
Query: 194 KLYDCRSNETIMTV-NHGSPVESTLFLPSGGIFISAGGTE--IKVWDIFNGGKLLSNISQ 250
K++ + + +++ H PV + + G I+ G + +K+W + + G ++
Sbjct: 574 KIFYVDTLKFFLSLYGHKLPV-ICMDISHDGALIATGSADRNVKIWGL-DFGDCHKSLFA 631
Query: 251 HHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID-FPNAILSMAISEHDDILT 309
H +V L+ + +A D +K +D F+ + ++ I +A+S D +
Sbjct: 632 HDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVV 691
Query: 310 VGMMDGIISIRKR-EEPVRQSEKRK 333
D + + +R EP+ E+R+
Sbjct: 692 SSSHDKSLRLWERTREPLILEEERE 716
Score = 52.8 bits (121), Expect = 3e-06
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 91 CFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQL--KIISYSDDK 148
C DG L G E+ ++++F + S F GH + T DQL ++ S S D
Sbjct: 72 CPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAI--TTLKYDQLGGRLASGSKDT 129
Query: 149 SVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT-V 207
+ +WD+ E + H D I A +++++ D VK +D + T V
Sbjct: 130 DIIVWDVINESGLYRLKGHKDAI-TQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMV 188
Query: 208 NHGSPVESTLFLPSGGIFIS-AGGTEIKVWDI 238
H + V + L I+ A +E++VWDI
Sbjct: 189 GHRTEVWGLVLLSEEKRLITGASDSELRVWDI 220
Score = 37.1 bits (82), Expect = 0.15
Identities = 23/111 (20%), Positives = 50/111 (45%), Gaps = 1/111 (0%)
Query: 68 VYDPVTKVVAKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTG 127
V+D + + + +A F + LLV ++ VK +D+ +++ + GH
Sbjct: 133 VWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRT 192
Query: 128 PVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASP 178
V ++ ++I+ + D + +WDI+ + I + E D + +SP
Sbjct: 193 EVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIED-PEEPDPKKIKGSSP 242
Score = 34.7 bits (76), Expect = 0.81
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 193 VKLYDCRSNETIMTVNHGSPVESTLFLPS-GGIFISAGGTE--IKVWDIFNG-GKLLSNI 248
V ++D R E I+ + G E T PS G+ ++ G + I+++ + +G G + N
Sbjct: 47 VFIWDLRKGEKILILQ-GLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFN- 104
Query: 249 SQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
H +TTL+ RL S S D + ++DV
Sbjct: 105 -GHKAAITTLKYDQLGGRLASGSKDTDIIVWDV 136
>BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein.
Length = 297
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 12/210 (5%)
Query: 77 AKNISKFVEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTK 136
A+ + K + A C LV+G+E V ++++ LR GH ++ +
Sbjct: 11 AEQLKKQIADARKACADVTLAELVSGLE--VVGRVQMRTRRTLR---GHLAKIYAMHWAT 65
Query: 137 DQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLY 196
D ++S S D + +WD T ++ + ++ A +P S + + G D+ +Y
Sbjct: 66 DSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP-SGNFVACGGLDNMCSIY 124
Query: 197 DCRSNETIMTVN-----HGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQH 251
+ +S E + V+ H + FL I S+G T +WDI G + + H
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVG-H 183
Query: 252 HKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+L ++ + + +S + D K++DV
Sbjct: 184 TGDCMSLAVSPDFNLFISGACDASAKLWDV 213
Score = 49.2 bits (112), Expect = 4e-05
Identities = 36/153 (23%), Positives = 64/153 (41%), Gaps = 3/153 (1%)
Query: 88 YGGCFR-ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSD 146
Y C R D +V + L+D+++ VF GHTG + D IS +
Sbjct: 145 YLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 204
Query: 147 DKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMT 206
D S LWD+ F H I A +S ++ +G D ++D +E +
Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFSLSGRLLFAGYDDFNCNVWDSMKSERVGI 264
Query: 207 VNHGSPVESTLFLPSGGIFISAGGTE--IKVWD 237
++ S L + + G+ ++ G + +K+W+
Sbjct: 265 LSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 297
>BC047921-1|AAH47921.1| 563|Homo sapiens WDR86 protein protein.
Length = 563
Score = 56.8 bits (131), Expect = 2e-07
Identities = 58/225 (25%), Positives = 95/225 (42%), Gaps = 21/225 (9%)
Query: 105 EAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANF 164
+ ++ +DV + L+V+ GHT V+R +QL SY D++ +W + + F
Sbjct: 263 DCTIRRWDVLTGQCLQVYRGHTSIVNRILVANNQLFSSSY--DRTARVWSVDKGQMSREF 320
Query: 165 NEHTDYIRAGAAS-----PISP--------DIILSGSYDHTVKLYDCRSNETIMTVNHGS 211
H + + A S P +P ++++GS D T K++ S T+ +
Sbjct: 321 RGHRNCVLTLAYSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHT 380
Query: 212 PVESTLFLPSGGIFISAGGTE--IKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMS 269
L L + G G T+ I+ WDI + G+ L +H +V L L N + S
Sbjct: 381 GAVLCLVLDTPGHTAFTGSTDATIRAWDILS-GEQLRVFREHRGSVICLELV--NRLVYS 437
Query: 270 ASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVGMMD 314
S DR VK + T + V +S A+ H L G D
Sbjct: 438 GSADRTVKCWLADTGECVRTFTAHRRNVS-ALKYHAGTLFTGSGD 481
Score = 55.2 bits (127), Expect = 5e-07
Identities = 47/188 (25%), Positives = 80/188 (42%), Gaps = 6/188 (3%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
A G LLV G + K++ V S + GHTG V + S D ++ W
Sbjct: 348 AAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAW 407
Query: 154 DISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPV 213
DI + E++ F EH + + ++ SGS D TVK + + E + T
Sbjct: 408 DILSGEQLRVFREHRGSV---ICLELVNRLVYSGSADRTVKCWLADTGECVRTFTAHRRN 464
Query: 214 ESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLD 273
S L +G +F +G + +D +G L + + H + + + L +AS D
Sbjct: 465 VSALKYHAGTLFTGSGDACARAFDAQSGE--LRRVFRGHTFIINC-IQVHGQVLYTASHD 521
Query: 274 RHVKIYDV 281
++++DV
Sbjct: 522 GALRLWDV 529
>EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein.
Length = 513
Score = 56.4 bits (130), Expect = 2e-07
Identities = 40/162 (24%), Positives = 78/162 (48%), Gaps = 10/162 (6%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNIS-----KFV---EAAYGGCFRADGRLLVA 101
FSP Y + ++V++ T + K++ F+ +A CF D +L
Sbjct: 222 FSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLAT 281
Query: 102 GIEEAAVKLFDVQSKNVLRVF-TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEER 160
G ++ +K++ +QS LR F H+ V F+KD +I+S S D+++ + + + +
Sbjct: 282 GAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKT 341
Query: 161 IANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
+ F H+ ++ A I+S S D TVK+++ ++ E
Sbjct: 342 LKEFRGHSSFVNE-ATFTQDGHYIISASSDGTVKIWNMKTTE 382
Score = 46.0 bits (104), Expect = 3e-04
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 5/117 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F D +++ + +++ ++S L+ F GH+ V+ FT+D IIS S D +V
Sbjct: 315 FSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVK 374
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN 208
+W++ T E F AG ++ I+L + +H V C + T++ +N
Sbjct: 375 IWNMKTTECSNTFKSLGS--TAGTDITVNSVILLPKNPEHFVV---CNRSNTVVIMN 426
Score = 39.1 bits (87), Expect = 0.038
Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 232 EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID 291
+IKVW I +G L H K VT L + ++S+++SAS D+ ++I+ + + K +
Sbjct: 287 KIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR 346
Query: 292 FPNAILSMAISEHD-DILTVGMMDGIISI 319
++ ++ A D + DG + I
Sbjct: 347 GHSSFVNEATFTQDGHYIISASSDGTVKI 375
>BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 56.4 bits (130), Expect = 2e-07
Identities = 40/162 (24%), Positives = 78/162 (48%), Gaps = 10/162 (6%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNIS-----KFV---EAAYGGCFRADGRLLVA 101
FSP Y + ++V++ T + K++ F+ +A CF D +L
Sbjct: 222 FSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLAT 281
Query: 102 GIEEAAVKLFDVQSKNVLRVF-TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEER 160
G ++ +K++ +QS LR F H+ V F+KD +I+S S D+++ + + + +
Sbjct: 282 GAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKT 341
Query: 161 IANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
+ F H+ ++ A I+S S D TVK+++ ++ E
Sbjct: 342 LKEFRGHSSFVNE-ATFTQDGHYIISASSDGTVKIWNMKTTE 382
Score = 46.0 bits (104), Expect = 3e-04
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 5/117 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F D +++ + +++ ++S L+ F GH+ V+ FT+D IIS S D +V
Sbjct: 315 FSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVK 374
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN 208
+W++ T E F AG ++ I+L + +H V C + T++ +N
Sbjct: 375 IWNMKTTECSNTFKSLGS--TAGTDITVNSVILLPKNPEHFVV---CNRSNTVVIMN 426
Score = 39.1 bits (87), Expect = 0.038
Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 232 EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID 291
+IKVW I +G L H K VT L + ++S+++SAS D+ ++I+ + + K +
Sbjct: 287 KIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR 346
Query: 292 FPNAILSMAISEHD-DILTVGMMDGIISI 319
++ ++ A D + DG + I
Sbjct: 347 GHSSFVNEATFTQDGHYIISASSDGTVKI 375
>BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 56.4 bits (130), Expect = 2e-07
Identities = 40/162 (24%), Positives = 78/162 (48%), Gaps = 10/162 (6%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNIS-----KFV---EAAYGGCFRADGRLLVA 101
FSP Y + ++V++ T + K++ F+ +A CF D +L
Sbjct: 222 FSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLAT 281
Query: 102 GIEEAAVKLFDVQSKNVLRVF-TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEER 160
G ++ +K++ +QS LR F H+ V F+KD +I+S S D+++ + + + +
Sbjct: 282 GAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKT 341
Query: 161 IANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
+ F H+ ++ A I+S S D TVK+++ ++ E
Sbjct: 342 LKEFRGHSSFVNE-ATFTQDGHYIISASSDGTVKIWNMKTTE 382
Score = 46.0 bits (104), Expect = 3e-04
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 5/117 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F D +++ + +++ ++S L+ F GH+ V+ FT+D IIS S D +V
Sbjct: 315 FSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVK 374
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN 208
+W++ T E F AG ++ I+L + +H V C + T++ +N
Sbjct: 375 IWNMKTTECSNTFKSLGS--TAGTDITVNSVILLPKNPEHFVV---CNRSNTVVIMN 426
Score = 39.1 bits (87), Expect = 0.038
Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 232 EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID 291
+IKVW I +G L H K VT L + ++S+++SAS D+ ++I+ + + K +
Sbjct: 287 KIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR 346
Query: 292 FPNAILSMAISEHD-DILTVGMMDGIISI 319
++ ++ A D + DG + I
Sbjct: 347 GHSSFVNEATFTQDGHYIISASSDGTVKI 375
>AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 56.4 bits (130), Expect = 2e-07
Identities = 40/162 (24%), Positives = 78/162 (48%), Gaps = 10/162 (6%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNIS-----KFV---EAAYGGCFRADGRLLVA 101
FSP Y + ++V++ T + K++ F+ +A CF D +L
Sbjct: 222 FSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLAT 281
Query: 102 GIEEAAVKLFDVQSKNVLRVF-TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEER 160
G ++ +K++ +QS LR F H+ V F+KD +I+S S D+++ + + + +
Sbjct: 282 GAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKT 341
Query: 161 IANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
+ F H+ ++ A I+S S D TVK+++ ++ E
Sbjct: 342 LKEFRGHSSFVNE-ATFTQDGHYIISASSDGTVKIWNMKTTE 382
Score = 46.0 bits (104), Expect = 3e-04
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 5/117 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F D +++ + +++ ++S L+ F GH+ V+ FT+D IIS S D +V
Sbjct: 315 FSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVK 374
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN 208
+W++ T E F AG ++ I+L + +H V C + T++ +N
Sbjct: 375 IWNMKTTECSNTFKSLGS--TAGTDITVNSVILLPKNPEHFVV---CNRSNTVVIMN 426
Score = 39.1 bits (87), Expect = 0.038
Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 232 EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID 291
+IKVW I +G L H K VT L + ++S+++SAS D+ ++I+ + + K +
Sbjct: 287 KIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR 346
Query: 292 FPNAILSMAISEHD-DILTVGMMDGIISI 319
++ ++ A D + DG + I
Sbjct: 347 GHSSFVNEATFTQDGHYIISASSDGTVKI 375
>AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens
cDNA FLJ10805 fis, clone NT2RP4000839, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 513
Score = 56.4 bits (130), Expect = 2e-07
Identities = 40/162 (24%), Positives = 78/162 (48%), Gaps = 10/162 (6%)
Query: 50 FSPVEPYYFAATCSVRVQVYDPVTKVVAKNIS-----KFV---EAAYGGCFRADGRLLVA 101
FSP Y + ++V++ T + K++ F+ +A CF D +L
Sbjct: 222 FSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLAT 281
Query: 102 GIEEAAVKLFDVQSKNVLRVF-TGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEER 160
G ++ +K++ +QS LR F H+ V F+KD +I+S S D+++ + + + +
Sbjct: 282 GAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKT 341
Query: 161 IANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNE 202
+ F H+ ++ A I+S S D TVK+++ ++ E
Sbjct: 342 LKEFRGHSSFVNE-ATFTQDGHYIISASSDGTVKIWNMKTTE 382
Score = 46.0 bits (104), Expect = 3e-04
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 5/117 (4%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
F D +++ + +++ ++S L+ F GH+ V+ FT+D IIS S D +V
Sbjct: 315 FSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVK 374
Query: 152 LWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN 208
+W++ T E F AG ++ I+L + +H V C + T++ +N
Sbjct: 375 IWNMKTTECSNTFKSLGS--TAGTDITVNSVILLPKNPEHFVV---CNRSNTVVIMN 426
Score = 39.1 bits (87), Expect = 0.038
Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 232 EIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNID 291
+IKVW I +G L H K VT L + ++S+++SAS D+ ++I+ + + K +
Sbjct: 287 KIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFR 346
Query: 292 FPNAILSMAISEHD-DILTVGMMDGIISI 319
++ ++ A D + DG + I
Sbjct: 347 GHSSFVNEATFTQDGHYIISASSDGTVKI 375
>AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD repeat
protein protein.
Length = 631
Score = 56.4 bits (130), Expect = 2e-07
Identities = 59/236 (25%), Positives = 97/236 (41%), Gaps = 11/236 (4%)
Query: 30 WKKLGLP---VLVKEFGAIDYLD---FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKF 83
WK LGLP VL+ FG D+L F P ++ V+++D T
Sbjct: 376 WKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGH 435
Query: 84 VEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS 143
A + + + G + + + K++DV S+ GHT V+ F +++
Sbjct: 436 SRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLT 495
Query: 144 YSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNET 203
S DK++ +WD T + H I P +I S KL+D R
Sbjct: 496 SSADKTLSIWDARTGICEQSLYGHMHSINDAIFDP-RGHMIASCDACGVTKLWDFRKLLP 554
Query: 204 IMTVNHG-SPVESTLFLPSGGIFISAGGT-EIKVWDIFNG--GKLLSNISQHHKTV 255
I++++ G SP F SG + A G I + D+ +G KL+ + ++ H V
Sbjct: 555 IVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVV 610
Score = 52.4 bits (120), Expect = 4e-06
Identities = 40/146 (27%), Positives = 63/146 (43%), Gaps = 3/146 (2%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
+LV+ E+ K+ + NVL GHT + F K+ + S D +V LWD+ T
Sbjct: 366 ILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCT 425
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVEST 216
+ I F H+ + + + + S S D T K++D S T+ H V S
Sbjct: 426 GDCILTFEGHSRAVWSCTWHSCG-NFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSI 484
Query: 217 LFLP-SGGIFISAGGTEIKVWDIFNG 241
F P S + S+ + +WD G
Sbjct: 485 EFFPFSNTLLTSSADKTLSIWDARTG 510
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Query: 182 DIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGG-IFISAGGTEIKVWDIF 239
DI++S D K+ ++T H + F PSG + S+G T +K+WD+
Sbjct: 365 DILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLC 424
Query: 240 NGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
G +L+ H + V + S + + S+SLD+ KI+DV++
Sbjct: 425 TGDCILT-FEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS 467
>AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein.
Length = 631
Score = 56.4 bits (130), Expect = 2e-07
Identities = 59/236 (25%), Positives = 97/236 (41%), Gaps = 11/236 (4%)
Query: 30 WKKLGLP---VLVKEFGAIDYLD---FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKF 83
WK LGLP VL+ FG D+L F P ++ V+++D T
Sbjct: 376 WKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGH 435
Query: 84 VEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS 143
A + + + G + + + K++DV S+ GHT V+ F +++
Sbjct: 436 SRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLT 495
Query: 144 YSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNET 203
S DK++ +WD T + H I P +I S KL+D R
Sbjct: 496 SSADKTLSIWDARTGICEQSLYGHMHSINDAIFDP-RGHMIASCDACGVTKLWDFRKLLP 554
Query: 204 IMTVNHG-SPVESTLFLPSGGIFISAGGT-EIKVWDIFNG--GKLLSNISQHHKTV 255
I++++ G SP F SG + A G I + D+ +G KL+ + ++ H V
Sbjct: 555 IVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVV 610
Score = 52.4 bits (120), Expect = 4e-06
Identities = 40/146 (27%), Positives = 63/146 (43%), Gaps = 3/146 (2%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
+LV+ E+ K+ + NVL GHT + F K+ + S D +V LWD+ T
Sbjct: 366 ILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCT 425
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVEST 216
+ I F H+ + + + + S S D T K++D S T+ H V S
Sbjct: 426 GDCILTFEGHSRAVWSCTWHSCG-NFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSI 484
Query: 217 LFLP-SGGIFISAGGTEIKVWDIFNG 241
F P S + S+ + +WD G
Sbjct: 485 EFFPFSNTLLTSSADKTLSIWDARTG 510
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Query: 182 DIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGG-IFISAGGTEIKVWDIF 239
DI++S D K+ ++T H + F PSG + S+G T +K+WD+
Sbjct: 365 DILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLC 424
Query: 240 NGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
G +L+ H + V + S + + S+SLD+ KI+DV++
Sbjct: 425 TGDCILT-FEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS 467
>BC024267-1|AAH24267.1| 594|Homo sapiens TRAF7 protein protein.
Length = 594
Score = 56.0 bits (129), Expect = 3e-07
Identities = 57/201 (28%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Query: 122 FTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISP 181
F GH GPV + S S DK++ +WD T + E D I A I
Sbjct: 316 FVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGI--VLALCIQG 373
Query: 182 DIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGTEIKVWDIFN 240
+ SGS D T+ ++D ++ + + T+ H +PV TL + S + S IKVWDI
Sbjct: 374 CKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPV-CTL-VSSHNVLFSGSLKAIKVWDIVG 431
Query: 241 GG-KLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFP-NAILS 298
KL ++ + V L A S L S S + +KI+D+ T +H + ++ S
Sbjct: 432 TELKLKKELTGLNHWVRALVAA--QSYLYSGSY-QTIKIWDIRTLDCIHVLQTSGGSVYS 488
Query: 299 MAISEHDDILTVGMMDGIISI 319
+A++ H + G + +I +
Sbjct: 489 IAVTNHH--IVCGTYENLIHV 507
Score = 55.2 bits (127), Expect = 5e-07
Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 99 LVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVH--RTFFTKDQLKIISYSDDKSVGLWDIS 156
+V G E + ++D++SK +R TGH G V+ T DQ K+ S S D+S+ +W +
Sbjct: 496 IVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMD 555
Query: 157 TEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC 198
H + A A +S + SG+ D TVK++ C
Sbjct: 556 NMICTQTLLRHQGSVTALA---VSRGRLFSGAVDSTVKVWTC 594
Score = 44.8 bits (101), Expect = 8e-04
Identities = 42/190 (22%), Positives = 87/190 (45%), Gaps = 12/190 (6%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G L +G + + ++D+Q+ + H PV + + ++ K++ +WDI
Sbjct: 373 GCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSHN---VLFSGSLKAIKVWDI 429
Query: 156 -STEERI-ANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPV 213
TE ++ ++RA A + + SGSY T+K++D R+ + I +
Sbjct: 430 VGTELKLKKELTGLNHWVRALVA---AQSYLYSGSY-QTIKIWDIRTLDCIHVLQTSGGS 485
Query: 214 ESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS--NNSRLMSAS 271
++ + + I I VWDI + + ++ H TV L + S + +++ SAS
Sbjct: 486 VYSIAVTNHHIVCGTYENLIHVWDI-ESKEQVRTLTGHVGTVYALAVISTPDQTKVFSAS 544
Query: 272 LDRHVKIYDV 281
DR ++++ +
Sbjct: 545 YDRSLRVWSM 554
Score = 36.7 bits (81), Expect = 0.20
Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 9/131 (6%)
Query: 187 GSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLL 245
GSYD +++ C+ V H PV G + S + IKVWD K
Sbjct: 302 GSYDPQ-QIFKCKGT----FVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQ 356
Query: 246 SNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHD 305
+ H V L L +L S S D + ++D+ + V+ I + + +S H
Sbjct: 357 KTLEGHDGIV--LALCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSH- 413
Query: 306 DILTVGMMDGI 316
++L G + I
Sbjct: 414 NVLFSGSLKAI 424
>AY569455-1|AAS68363.1| 670|Homo sapiens TRAF7 protein.
Length = 670
Score = 56.0 bits (129), Expect = 3e-07
Identities = 57/201 (28%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Query: 122 FTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISP 181
F GH GPV + S S DK++ +WD T + E D I A I
Sbjct: 392 FVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGI--VLALCIQG 449
Query: 182 DIILSGSYDHTVKLYDCRSNETIMTVN-HGSPVESTLFLPSGGIFISAGGTEIKVWDIFN 240
+ SGS D T+ ++D ++ + + T+ H +PV TL + S + S IKVWDI
Sbjct: 450 CKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPV-CTL-VSSHNVLFSGSLKAIKVWDIVG 507
Query: 241 GG-KLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFP-NAILS 298
KL ++ + V L A S L S S + +KI+D+ T +H + ++ S
Sbjct: 508 TELKLKKELTGLNHWVRALVAA--QSYLYSGSY-QTIKIWDIRTLDCIHVLQTSGGSVYS 564
Query: 299 MAISEHDDILTVGMMDGIISI 319
+A++ H + G + +I +
Sbjct: 565 IAVTNHH--IVCGTYENLIHV 583
Score = 55.2 bits (127), Expect = 5e-07
Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 99 LVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVH--RTFFTKDQLKIISYSDDKSVGLWDIS 156
+V G E + ++D++SK +R TGH G V+ T DQ K+ S S D+S+ +W +
Sbjct: 572 IVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMD 631
Query: 157 TEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDC 198
H + A A +S + SG+ D TVK++ C
Sbjct: 632 NMICTQTLLRHQGSVTALA---VSRGRLFSGAVDSTVKVWTC 670
Score = 44.8 bits (101), Expect = 8e-04
Identities = 42/190 (22%), Positives = 87/190 (45%), Gaps = 12/190 (6%)
Query: 96 GRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDI 155
G L +G + + ++D+Q+ + H PV + + ++ K++ +WDI
Sbjct: 449 GCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSHN---VLFSGSLKAIKVWDI 505
Query: 156 -STEERI-ANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPV 213
TE ++ ++RA A + + SGSY T+K++D R+ + I +
Sbjct: 506 VGTELKLKKELTGLNHWVRALVA---AQSYLYSGSY-QTIKIWDIRTLDCIHVLQTSGGS 561
Query: 214 ESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLAS--NNSRLMSAS 271
++ + + I I VWDI + + ++ H TV L + S + +++ SAS
Sbjct: 562 VYSIAVTNHHIVCGTYENLIHVWDI-ESKEQVRTLTGHVGTVYALAVISTPDQTKVFSAS 620
Query: 272 LDRHVKIYDV 281
DR ++++ +
Sbjct: 621 YDRSLRVWSM 630
Score = 36.7 bits (81), Expect = 0.20
Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 9/131 (6%)
Query: 187 GSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTE-IKVWDIFNGGKLL 245
GSYD +++ C+ V H PV G + S + IKVWD K
Sbjct: 378 GSYDPQ-QIFKCKGT----FVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQ 432
Query: 246 SNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHD 305
+ H V L L +L S S D + ++D+ + V+ I + + +S H
Sbjct: 433 KTLEGHDGIV--LALCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSH- 489
Query: 306 DILTVGMMDGI 316
++L G + I
Sbjct: 490 NVLFSGSLKAI 500
>BC107125-1|AAI07126.1| 248|Homo sapiens WDR86 protein protein.
Length = 248
Score = 55.2 bits (127), Expect = 5e-07
Identities = 47/188 (25%), Positives = 80/188 (42%), Gaps = 6/188 (3%)
Query: 94 ADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLW 153
A G LLV G + K++ V S + GHTG V + S D ++ W
Sbjct: 33 AAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAW 92
Query: 154 DISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPV 213
DI + E++ F EH + + ++ SGS D TVK + + E + T
Sbjct: 93 DILSGEQLRVFREHRGSV---ICLELVNRLVYSGSADRTVKCWLADTGECVRTFTAHRRN 149
Query: 214 ESTLFLPSGGIFISAGGTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLD 273
S L +G +F +G + +D +G L + + H + + + L +AS D
Sbjct: 150 VSALKYHAGTLFTGSGDACARAFDAQSGE--LRRVFRGHTFIINC-IQVHGQVLYTASHD 206
Query: 274 RHVKIYDV 281
++++DV
Sbjct: 207 GALRLWDV 214
>CR456496-1|CAG30382.1| 327|Homo sapiens GNB1L protein.
Length = 327
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/146 (23%), Positives = 68/146 (46%), Gaps = 5/146 (3%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
LL+AG E+ +V L+DV + V H PV F + + IS S K++ +W +
Sbjct: 180 LLLAGYEDGSVVLWDVSEQKVCSRIACHEEPVMDLDFDSQKARGISGSAGKALAVWSLDW 239
Query: 158 EERIANFNEHTDYIRAGAAS-PISPD--IILSGSYDHTVKLYDCRSNETIMTVN-HGSPV 213
++ + H + G A I PD I+ + +DH ++++ R+ + + + H + V
Sbjct: 240 QQALQVRGTH-ELTNPGIAEVTIRPDRKILATAGWDHRIRVFHWRTMQPLAVLAFHSAAV 298
Query: 214 ESTLFLPSGGIFISAGGTEIKVWDIF 239
+ F G + + I +W ++
Sbjct: 299 QCVAFTADGLLAAGSKDQRISLWSLY 324
>BC012060-1|AAH12060.1| 327|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1-like protein.
Length = 327
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/146 (23%), Positives = 68/146 (46%), Gaps = 5/146 (3%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
LL+AG E+ +V L+DV + V H PV F + + IS S K++ +W +
Sbjct: 180 LLLAGYEDGSVVLWDVSEQKVCSRIACHEEPVMDLDFDSQKARGISGSAGKALAVWSLDW 239
Query: 158 EERIANFNEHTDYIRAGAAS-PISPD--IILSGSYDHTVKLYDCRSNETIMTVN-HGSPV 213
++ + H + G A I PD I+ + +DH ++++ R+ + + + H + V
Sbjct: 240 QQALQVRGTH-ELTNPGIAEVTIRPDRKILATAGWDHRIRVFHWRTMQPLAVLAFHSAAV 298
Query: 214 ESTLFLPSGGIFISAGGTEIKVWDIF 239
+ F G + + I +W ++
Sbjct: 299 QCVAFTADGLLAAGSKDQRISLWSLY 324
>AF301895-1|AAG53933.1| 327|Homo sapiens WDVCF protein.
Length = 327
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/146 (23%), Positives = 68/146 (46%), Gaps = 5/146 (3%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
LL+AG E+ +V L+DV + V H PV F + + IS S K++ +W +
Sbjct: 180 LLLAGYEDGSVVLWDVSEQKVCSRIACHEEPVMDLDFDSQKARGISGSAGKALAVWSLDW 239
Query: 158 EERIANFNEHTDYIRAGAAS-PISPD--IILSGSYDHTVKLYDCRSNETIMTVN-HGSPV 213
++ + H + G A I PD I+ + +DH ++++ R+ + + + H + V
Sbjct: 240 QQALQVRGTH-ELTNPGIAEVTIRPDRKILATAGWDHRIRVFHWRTMQPLAVLAFHSAAV 298
Query: 214 ESTLFLPSGGIFISAGGTEIKVWDIF 239
+ F G + + I +W ++
Sbjct: 299 QCVAFTADGLLAAGSKDQRISLWSLY 324
>AB051432-1|BAB33315.1| 386|Homo sapiens KIAA1645 protein protein.
Length = 386
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/146 (23%), Positives = 68/146 (46%), Gaps = 5/146 (3%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
LL+AG E+ +V L+DV + V H PV F + + IS S K++ +W +
Sbjct: 239 LLLAGYEDGSVVLWDVSEQKVCSRIACHEEPVMDLDFDSQKARGISGSAGKALAVWSLDW 298
Query: 158 EERIANFNEHTDYIRAGAAS-PISPD--IILSGSYDHTVKLYDCRSNETIMTVN-HGSPV 213
++ + H + G A I PD I+ + +DH ++++ R+ + + + H + V
Sbjct: 299 QQALQVRGTH-ELTNPGIAEVTIRPDRKILATAGWDHRIRVFHWRTMQPLAVLAFHSAAV 357
Query: 214 ESTLFLPSGGIFISAGGTEIKVWDIF 239
+ F G + + I +W ++
Sbjct: 358 QCVAFTADGLLAAGSKDQRISLWSLY 383
>AB049212-1|BAB68408.1| 327|Homo sapiens G-protein beta subunit
like protein protein.
Length = 327
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/146 (23%), Positives = 68/146 (46%), Gaps = 5/146 (3%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
LL+AG E+ +V L+DV + V H PV F + + IS S K++ +W +
Sbjct: 180 LLLAGYEDGSVVLWDVSEQKVCSRIACHEEPVMDLDFDSQKARGISGSAGKALAVWSLDW 239
Query: 158 EERIANFNEHTDYIRAGAAS-PISPD--IILSGSYDHTVKLYDCRSNETIMTVN-HGSPV 213
++ + H + G A I PD I+ + +DH ++++ R+ + + + H + V
Sbjct: 240 QQALQVRGTH-ELTNPGIAEVTIRPDRKILATAGWDHRIRVFHWRTMQPLAVLAFHSAAV 298
Query: 214 ESTLFLPSGGIFISAGGTEIKVWDIF 239
+ F G + + I +W ++
Sbjct: 299 QCVAFTADGLLAAGSKDQRISLWSLY 324
>BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein.
Length = 571
Score = 54.0 bits (124), Expect = 1e-06
Identities = 58/236 (24%), Positives = 96/236 (40%), Gaps = 11/236 (4%)
Query: 30 WKKLGLP---VLVKEFGAIDYLD---FSPVEPYYFAATCSVRVQVYDPVTKVVAKNISKF 83
WK LGLP VL+ FG D+L F P ++ V+++D
Sbjct: 316 WKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGH 375
Query: 84 VEAAYGGCFRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIIS 143
A + + + G + + + K++DV S+ GHT V+ F +++
Sbjct: 376 SRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLT 435
Query: 144 YSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNET 203
S DK++ +WD T + H I P +I S KL+D R
Sbjct: 436 SSADKTLSIWDARTGICEQSLYGHMHSINDAIFDP-RGHMIASCDACGVTKLWDFRKLLP 494
Query: 204 IMTVNHG-SPVESTLFLPSGGIFISAGGT-EIKVWDIFNG--GKLLSNISQHHKTV 255
I++++ G SP F SG + A G I + D+ +G KL+ + ++ H V
Sbjct: 495 IVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVV 550
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/146 (26%), Positives = 62/146 (42%), Gaps = 3/146 (2%)
Query: 98 LLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWDIST 157
+LV+ E+ K+ + NVL GHT + F K+ + S D +V LWD+
Sbjct: 306 ILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCK 365
Query: 158 EERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTV-NHGSPVEST 216
+ I F H+ + + + + S S D T K++D S T+ H V S
Sbjct: 366 GDCILTFEGHSRAVWSCTWHSCG-NFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSI 424
Query: 217 LFLP-SGGIFISAGGTEIKVWDIFNG 241
F P S + S+ + +WD G
Sbjct: 425 EFFPFSNTLLTSSADKTLSIWDARTG 450
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Query: 182 DIILSGSYDHTVKLYDCRSNETIMT-VNHGSPVESTLFLPSGG-IFISAGGTEIKVWDIF 239
DI++S D K+ ++T H + F PSG + S+G T +K+WD+
Sbjct: 305 DILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLC 364
Query: 240 NGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDVST 283
G +L+ H + V + S + + S+SLD+ KI+DV++
Sbjct: 365 KGDCILT-FEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS 407
>AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing
gene 21 protein.
Length = 271
Score = 54.0 bits (124), Expect = 1e-06
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 4/150 (2%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRV-FTGHTGPVHRTFFTKDQLK--IISYSDDK 148
F +D R +V+G + +KL++ V H+ V F+ + I+S DK
Sbjct: 67 FSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDK 126
Query: 149 SVGLWDISTEERIANFNEHTDYIRAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVN 208
V +W+++ + N HT Y+ SP + SG D L+D + + T++
Sbjct: 127 LVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGSLCASGGKDGQAMLWDLNEGKHLYTLD 185
Query: 209 HGSPVESTLFLPSGGIFISAGGTEIKVWDI 238
G + + F P+ +A G IK+WD+
Sbjct: 186 GGDIINALCFSPNRYWLCAATGPSIKIWDL 215
Score = 51.2 bits (117), Expect = 9e-06
Identities = 44/167 (26%), Positives = 78/167 (46%), Gaps = 9/167 (5%)
Query: 120 RVFTGHTGPVHRTFFTKDQLKIISYSDDKSVGLWD-ISTEERIANFNEHTDYIRAGAASP 178
R F GHT V F+ D +I+S S DK++ LW+ + + H++++ SP
Sbjct: 53 RRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSP 112
Query: 179 ISPD-IILSGSYDHTVKLYDCRSNETIMT--VNHGSPVESTLFLPSGGIFISAG-GTEIK 234
S + II+S +D VK+++ +N + T + H + + P G + S G +
Sbjct: 113 NSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAM 171
Query: 235 VWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSASLDRHVKIYDV 281
+WD+ N GK L + + S N + A+ +KI+D+
Sbjct: 172 LWDL-NEGKHLYTLD--GGDIINALCFSPNRYWLCAATGPSIKIWDL 215
>AK222483-1|BAD96203.1| 325|Homo sapiens eukaryotic translation
initiation factor 3, subunit 2 beta, 36kDa variant
protein.
Length = 325
Score = 54.0 bits (124), Expect = 1e-06
Identities = 50/231 (21%), Positives = 100/231 (43%), Gaps = 12/231 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ +G LL ++ V ++ + L + GHTG V D +++ S D S
Sbjct: 18 YNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCR 77
Query: 152 LWDISTEERIANFNEHTDYIRAG---AASPISPDIILSGSYDHTVKLYDCR------SNE 202
LWD T +++A ++ G + I Y V +D R +NE
Sbjct: 78 LWDCETGKQLALLKTNSAVRTCGFDFGGNTIMFSTDKQMGYQCFVSFFDLRDPSQIDNNE 137
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHHKTVTTLRL 260
M + + S + S ++ P G I+ + E+ + G++L N+ +H + + ++L
Sbjct: 138 PYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSA-KSGEVLVNVKEHSRQINDIQL 196
Query: 261 ASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVG 311
+ + + ++AS D K++D +T + + S A+S + D + +G
Sbjct: 197 SRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLG 247
Score = 39.9 bits (89), Expect = 0.022
Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 2/147 (1%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GH P+ + + ++ + + + D V +W ER+ + HT + A
Sbjct: 8 GHERPITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDAD-WDTKH 66
Query: 184 ILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGK 243
+L+GS D++ +L+DC + + + + S V + F GG I + + F
Sbjct: 67 VLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGF-DFGGNTIMFSTDKQMGYQCFVSFF 125
Query: 244 LLSNISQHHKTVTTLRLASNNSRLMSA 270
L + SQ +++ N+S++ SA
Sbjct: 126 DLRDPSQIDNNEPYMKIPCNDSKITSA 152
>U39067-1|AAC97144.1| 325|Homo sapiens translation initiation
factor eIF3 p36 subunit protein.
Length = 325
Score = 53.2 bits (122), Expect = 2e-06
Identities = 50/231 (21%), Positives = 100/231 (43%), Gaps = 12/231 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ +G LL ++ V ++ + L + GHTG V D +++ S D S
Sbjct: 18 YNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCR 77
Query: 152 LWDISTEERIANFNEHTDYIRAG---AASPISPDIILSGSYDHTVKLYDCR------SNE 202
LWD T +++A ++ G + I Y V +D R +NE
Sbjct: 78 LWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDNNE 137
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHHKTVTTLRL 260
M + + S + S ++ P G I+ + E+ + G++L N+ +H + + ++L
Sbjct: 138 PYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSA-KSGEVLVNVKEHSRQINDIQL 196
Query: 261 ASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVG 311
+ + + ++AS D K++D +T + + S A+S + D + +G
Sbjct: 197 SRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLG 247
Score = 37.9 bits (84), Expect = 0.087
Identities = 30/147 (20%), Positives = 65/147 (44%), Gaps = 2/147 (1%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GH + + + ++ + + + D V +W ER+ + HT + A
Sbjct: 8 GHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDAD-WDTKH 66
Query: 184 ILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGK 243
+L+GS D++ +L+DC + + + + S V + F G I + + ++ + F
Sbjct: 67 VLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMG-YQCFVSFF 125
Query: 244 LLSNISQHHKTVTTLRLASNNSRLMSA 270
L + SQ +++ N+S++ SA
Sbjct: 126 DLRDPSQIDNNEPYMKIPCNDSKITSA 152
>U36764-1|AAC50224.1| 325|Homo sapiens TGF-beta receptor
interacting protein 1 protein.
Length = 325
Score = 53.2 bits (122), Expect = 2e-06
Identities = 50/231 (21%), Positives = 100/231 (43%), Gaps = 12/231 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ +G LL ++ V ++ + L + GHTG V D +++ S D S
Sbjct: 18 YNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCR 77
Query: 152 LWDISTEERIANFNEHTDYIRAG---AASPISPDIILSGSYDHTVKLYDCR------SNE 202
LWD T +++A ++ G + I Y V +D R +NE
Sbjct: 78 LWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDNNE 137
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHHKTVTTLRL 260
M + + S + S ++ P G I+ + E+ + G++L N+ +H + + ++L
Sbjct: 138 PYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSA-KSGEVLVNVKEHSRQINDIQL 196
Query: 261 ASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVG 311
+ + + ++AS D K++D +T + + S A+S + D + +G
Sbjct: 197 SRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLG 247
Score = 37.9 bits (84), Expect = 0.087
Identities = 30/147 (20%), Positives = 65/147 (44%), Gaps = 2/147 (1%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GH + + + ++ + + + D V +W ER+ + HT + A
Sbjct: 8 GHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDAD-WDTKH 66
Query: 184 ILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGK 243
+L+GS D++ +L+DC + + + + S V + F G I + + ++ + F
Sbjct: 67 VLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMG-YQCFVSFF 125
Query: 244 LLSNISQHHKTVTTLRLASNNSRLMSA 270
L + SQ +++ N+S++ SA
Sbjct: 126 DLRDPSQIDNNEPYMKIPCNDSKITSA 152
>BT019597-1|AAV38404.1| 325|Homo sapiens eukaryotic translation
initiation factor 3, subunit 2 beta, 36kDa protein.
Length = 325
Score = 53.2 bits (122), Expect = 2e-06
Identities = 50/231 (21%), Positives = 100/231 (43%), Gaps = 12/231 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ +G LL ++ V ++ + L + GHTG V D +++ S D S
Sbjct: 18 YNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCR 77
Query: 152 LWDISTEERIANFNEHTDYIRAG---AASPISPDIILSGSYDHTVKLYDCR------SNE 202
LWD T +++A ++ G + I Y V +D R +NE
Sbjct: 78 LWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDNNE 137
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHHKTVTTLRL 260
M + + S + S ++ P G I+ + E+ + G++L N+ +H + + ++L
Sbjct: 138 PYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSA-KSGEVLVNVKEHSRQINDIQL 196
Query: 261 ASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVG 311
+ + + ++AS D K++D +T + + S A+S + D + +G
Sbjct: 197 SRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLG 247
Score = 37.9 bits (84), Expect = 0.087
Identities = 30/147 (20%), Positives = 65/147 (44%), Gaps = 2/147 (1%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GH + + + ++ + + + D V +W ER+ + HT + A
Sbjct: 8 GHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDAD-WDTKH 66
Query: 184 ILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGK 243
+L+GS D++ +L+DC + + + + S V + F G I + + ++ + F
Sbjct: 67 VLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMG-YQCFVSFF 125
Query: 244 LLSNISQHHKTVTTLRLASNNSRLMSA 270
L + SQ +++ N+S++ SA
Sbjct: 126 DLRDPSQIDNNEPYMKIPCNDSKITSA 152
>BC003140-1|AAH03140.1| 325|Homo sapiens eukaryotic translation
initiation factor 3, subunit 2 beta, 36kDa protein.
Length = 325
Score = 53.2 bits (122), Expect = 2e-06
Identities = 50/231 (21%), Positives = 100/231 (43%), Gaps = 12/231 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ +G LL ++ V ++ + L + GHTG V D +++ S D S
Sbjct: 18 YNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCR 77
Query: 152 LWDISTEERIANFNEHTDYIRAG---AASPISPDIILSGSYDHTVKLYDCR------SNE 202
LWD T +++A ++ G + I Y V +D R +NE
Sbjct: 78 LWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDNNE 137
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHHKTVTTLRL 260
M + + S + S ++ P G I+ + E+ + G++L N+ +H + + ++L
Sbjct: 138 PYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSA-KSGEVLVNVKEHSRQINDIQL 196
Query: 261 ASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVG 311
+ + + ++AS D K++D +T + + S A+S + D + +G
Sbjct: 197 SRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLG 247
Score = 37.9 bits (84), Expect = 0.087
Identities = 30/147 (20%), Positives = 65/147 (44%), Gaps = 2/147 (1%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GH + + + ++ + + + D V +W ER+ + HT + A
Sbjct: 8 GHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDAD-WDTKH 66
Query: 184 ILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGK 243
+L+GS D++ +L+DC + + + + S V + F G I + + ++ + F
Sbjct: 67 VLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMG-YQCFVSFF 125
Query: 244 LLSNISQHHKTVTTLRLASNNSRLMSA 270
L + SQ +++ N+S++ SA
Sbjct: 126 DLRDPSQIDNNEPYMKIPCNDSKITSA 152
>BC000413-1|AAH00413.1| 325|Homo sapiens eukaryotic translation
initiation factor 3, subunit 2 beta, 36kDa protein.
Length = 325
Score = 53.2 bits (122), Expect = 2e-06
Identities = 50/231 (21%), Positives = 100/231 (43%), Gaps = 12/231 (5%)
Query: 92 FRADGRLLVAGIEEAAVKLFDVQSKNVLRVFTGHTGPVHRTFFTKDQLKIISYSDDKSVG 151
+ +G LL ++ V ++ + L + GHTG V D +++ S D S
Sbjct: 18 YNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCR 77
Query: 152 LWDISTEERIANFNEHTDYIRAG---AASPISPDIILSGSYDHTVKLYDCR------SNE 202
LWD T +++A ++ G + I Y V +D R +NE
Sbjct: 78 LWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDNNE 137
Query: 203 TIMTVN-HGSPVESTLFLPSGGIFISAGGT-EIKVWDIFNGGKLLSNISQHHKTVTTLRL 260
M + + S + S ++ P G I+ + E+ + G++L N+ +H + + ++L
Sbjct: 138 PYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSA-KSGEVLVNVKEHSRQINDIQL 196
Query: 261 ASNNSRLMSASLDRHVKIYDVSTFKVVHNIDFPNAILSMAISEHDDILTVG 311
+ + + ++AS D K++D +T + + S A+S + D + +G
Sbjct: 197 SRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLG 247
Score = 37.9 bits (84), Expect = 0.087
Identities = 30/147 (20%), Positives = 65/147 (44%), Gaps = 2/147 (1%)
Query: 124 GHTGPVHRTFFTKDQLKIISYSDDKSVGLWDISTEERIANFNEHTDYIRAGAASPISPDI 183
GH + + + ++ + + + D V +W ER+ + HT + A
Sbjct: 8 GHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDAD-WDTKH 66
Query: 184 ILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSGGIFISAGGTEIKVWDIFNGGK 243
+L+GS D++ +L+DC + + + + S V + F G I + + ++ + F
Sbjct: 67 VLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMG-YQCFVSFF 125
Query: 244 LLSNISQHHKTVTTLRLASNNSRLMSA 270
L + SQ +++ N+S++ SA
Sbjct: 126 DLRDPSQIDNNEPYMKIPCNDSKITSA 152
>AY295082-1|AAQ63174.1| 544|Homo sapiens pre-mRNA splicing
factor-like protein protein.
Length = 544
Score = 53.2 bits (122), Expect = 2e-06
Identities = 54/232 (23%), Positives = 97/232 (41%), Gaps = 15/232 (6%)
Query: 116 KNVLRVFTGHTGPVHRTFFTKDQLK---IISYSDDKSVGLWD-ISTEERIANFNEHTDYI 171
+ VL GH GPV+ + K ++S S DK+ +W+ + + + ++ HT+ +
Sbjct: 236 RKVLFHLRGHRGPVNTIQWCPVLSKSHMLLSTSMDKTFKVWNAVDSGHCLQTYSLHTEAV 295
Query: 172 RAGAASPISPDIILSGSYDHTVKLYDCRSNETIMTVNHGSPVESTLFLPSG-GIFISAG- 229
RA +P I LSG +D + L D + + + + + F P IF+ G
Sbjct: 296 RAARWAPCGRRI-LSGGFDFALHLTDLETGTQLFSGRSDFRITTLKFHPKDHNIFLCGGF 354
Query: 230 GTEIKVWDIFNGGKLLSNISQHHKTVTTLRLASNNSRLMSA------SLDRHVKIYDVST 283
+E+K WDI G + S + +T+ L L + L S S DR + +D T
Sbjct: 355 SSEMKAWDIRTGKVMRSYKATIQQTLDILFLREGSEFLSSTDASTRDSADRTIIAWDFRT 414
Query: 284 FKVVHNIDFPNAIL--SMAISEHDDILTVGMMDGIISIRKREEPVRQSEKRK 333
+ N F S+A+ + + +++ P R +R+
Sbjct: 415 SAKISNQIFHERFTCPSLALHPREPVFLAQTNGNYLALFSTVWPYRMIRRRR 466
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.136 0.387
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 68,151,943
Number of Sequences: 224733
Number of extensions: 2697105
Number of successful extensions: 10271
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 495
Number of HSP's successfully gapped in prelim test: 379
Number of HSP's that attempted gapping in prelim test: 6173
Number of HSP's gapped (non-prelim): 2701
length of query: 527
length of database: 73,234,838
effective HSP length: 93
effective length of query: 434
effective length of database: 52,334,669
effective search space: 22713246346
effective search space used: 22713246346
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)
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