Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001506-TA|BGIBMGA001506-PA|IPR013818|Lipase, N-terminal,
IPR000734|Lipase, IPR002035|von Willebrand factor, type A
(293 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M93284-1|AAA59533.1| 469|Homo sapiens lipase related protein 2 ... 129 1e-29
CR456949-1|CAG33230.1| 469|Homo sapiens PNLIPRP2 protein. 129 1e-29
BC005989-1|AAH05989.1| 469|Homo sapiens PNLIPRP2 protein protein. 129 1e-29
M93285-1|AAA60129.1| 465|Homo sapiens lipase protein. 122 1e-27
L24529-1|AAA99053.1| 465|Homo sapiens pancreatic lipase protein. 122 1e-27
J05125-1|AAA36740.1| 465|Homo sapiens protein ( Human triglycer... 122 1e-27
BC014309-1|AAH14309.1| 465|Homo sapiens pancreatic lipase protein. 122 1e-27
AL731653-1|CAH72667.1| 465|Homo sapiens pancreatic lipase protein. 122 1e-27
U37591-1|AAC99994.1| 456|Homo sapiens nmd protein. 116 7e-26
AF035269-1|AAC98922.1| 376|Homo sapiens phosphatidylserine-spec... 116 7e-26
AF035268-1|AAC98921.1| 456|Homo sapiens phosphatidylserine-spec... 116 7e-26
AK222705-1|BAD96425.1| 456|Homo sapiens phospholipase A1 member... 115 2e-25
BC060825-1|AAH60825.1| 500|Homo sapiens lipase, endothelial pro... 113 7e-25
AY358928-1|AAQ89287.1| 354|Homo sapiens lipoprotein lipase H pr... 113 7e-25
AK125344-1|BAC86139.1| 390|Homo sapiens protein ( Homo sapiens ... 113 7e-25
AF118767-1|AAD30434.1| 500|Homo sapiens endothelial lipase prot... 113 7e-25
M35433-1|AAA59521.1| 499|Homo sapiens hepatic lipase protein. 111 3e-24
J03540-1|AAA59520.1| 499|Homo sapiens LIPC protein. 111 3e-24
D83548-1|BAA12014.1| 499|Homo sapiens hepatic triglyceride lipa... 111 3e-24
X07228-1|CAA30188.1| 499|Homo sapiens protein ( Human mRNA for ... 111 4e-24
M29194-1|AAB60702.1| 499|Homo sapiens protein ( Human triglycer... 111 4e-24
J03895-1|AAA61165.1| 499|Homo sapiens LIPC protein. 111 4e-24
BC132825-1|AAI32826.1| 499|Homo sapiens lipase, hepatic protein. 111 4e-24
EF186229-1|ABM67095.1| 451|Homo sapiens lipase H protein. 107 3e-23
BC064941-1|AAH64941.1| 451|Homo sapiens lipase, member H protein. 107 3e-23
AY093498-1|AAM18803.1| 451|Homo sapiens lipase H protein. 107 3e-23
AY036912-1|AAK63178.1| 451|Homo sapiens membrane-bound phosphat... 107 3e-23
CR457054-1|CAG33335.1| 475|Homo sapiens LPL protein. 105 1e-22
BC047703-1|AAH47703.1| 440|Homo sapiens PLA1A protein protein. 105 2e-22
X54516-1|CAA38372.1| 475|Homo sapiens protein ( Human mRNA for ... 104 3e-22
X14390-1|CAA32564.1| 475|Homo sapiens protein ( Human mRNA for ... 104 3e-22
M15856-1|AAB59536.1| 475|Homo sapiens LPL protein. 104 3e-22
BT006726-1|AAP35372.1| 475|Homo sapiens lipoprotein lipase prot... 104 3e-22
BC011353-1|AAH11353.1| 475|Homo sapiens lipoprotein lipase prot... 104 3e-22
AK222464-1|BAD96184.1| 475|Homo sapiens lipoprotein lipase prec... 104 3e-22
M93283-1|AAA59532.1| 467|Homo sapiens lipase related protein 1 ... 104 4e-22
BC025784-1|AAH25784.1| 467|Homo sapiens pancreatic lipase-relat... 104 4e-22
AY197607-1|AAP37476.1| 481|Homo sapiens membrane-associated pho... 103 7e-22
BC117224-1|AAI17225.1| 467|Homo sapiens pancreatic lipase-relat... 100 1e-20
AK074229-1|BAB85023.1| 323|Homo sapiens protein ( Homo sapiens ... 94 5e-19
AF050163-1|AAC61679.1| 332|Homo sapiens lipoprotein lipase prec... 83 1e-15
AY918476-1|AAX14040.1| 140|Homo sapiens membrane-associated pho... 62 2e-09
EF186228-1|ABM67094.1| 417|Homo sapiens mutant lipase H protein. 53 1e-06
EF186230-1|ABM67096.1| 33|Homo sapiens lipase H protein. 36 0.17
>M93284-1|AAA59533.1| 469|Homo sapiens lipase related protein 2
protein.
Length = 469
Score = 129 bits (312), Expect = 1e-29
Identities = 73/211 (34%), Positives = 100/211 (47%), Gaps = 8/211 (3%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLS-TRNTEPNPTIRNAFL 106
++ L+T N Q + T I+HG+L ++ P+ + F
Sbjct: 55 RFLLYTNENPNNFQLITGTEPDTIEASNFQLDRKTRFIIHGFLDKAEDSWPSDMCKKMF- 113
Query: 107 NKADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLG 166
VN I VDW + SR+ YT + L+ G + ++H+ G SLG
Sbjct: 114 EVEKVNCICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQALSTQLGYSLEDVHVIGHSLG 173
Query: 167 AHVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGS----TSG 220
AH AGR LGGRV RITGLDPAGP + RL P D V+V+ IHTD S + G
Sbjct: 174 AHTAAEAGRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSSPIVPSLG 233
Query: 221 LGIGSAIARTDFFPNGGNSQPGCSTSLCTTI 251
G+ + DFFPNGG PGC ++ +TI
Sbjct: 234 FGMSQKVGHLDFFPNGGKEMPGCKKNVLSTI 264
>CR456949-1|CAG33230.1| 469|Homo sapiens PNLIPRP2 protein.
Length = 469
Score = 129 bits (312), Expect = 1e-29
Identities = 73/211 (34%), Positives = 100/211 (47%), Gaps = 8/211 (3%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLS-TRNTEPNPTIRNAFL 106
++ L+T N Q + T I+HG+L ++ P+ + F
Sbjct: 55 RFLLYTNENPNNFQLITGTEPDTIEASNFQLDRKTRFIIHGFLDKAEDSWPSDMCKKMF- 113
Query: 107 NKADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLG 166
VN I VDW + SR+ YT + L+ G + ++H+ G SLG
Sbjct: 114 EVEKVNCICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQALSTQLGYSLEDVHVIGHSLG 173
Query: 167 AHVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGS----TSG 220
AH AGR LGGRV RITGLDPAGP + RL P D V+V+ IHTD S + G
Sbjct: 174 AHTAAEAGRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSSPIVPSLG 233
Query: 221 LGIGSAIARTDFFPNGGNSQPGCSTSLCTTI 251
G+ + DFFPNGG PGC ++ +TI
Sbjct: 234 FGMSQKVGHLDFFPNGGKEMPGCKKNVLSTI 264
>BC005989-1|AAH05989.1| 469|Homo sapiens PNLIPRP2 protein protein.
Length = 469
Score = 129 bits (312), Expect = 1e-29
Identities = 73/211 (34%), Positives = 100/211 (47%), Gaps = 8/211 (3%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLS-TRNTEPNPTIRNAFL 106
++ L+T N Q + T I+HG+L ++ P+ + F
Sbjct: 55 RFLLYTNENPNNFQLITGTEPDTIEASNFQLDRKTRFIIHGFLDKAEDSWPSDMCKKMF- 113
Query: 107 NKADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLG 166
VN I VDW + SR+ YT + L+ G + ++H+ G SLG
Sbjct: 114 EVEKVNCICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQALSTQLGYSLEDVHVIGHSLG 173
Query: 167 AHVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGS----TSG 220
AH AGR LGGRV RITGLDPAGP + RL P D V+V+ IHTD S + G
Sbjct: 174 AHTAAEAGRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSSPIVPSLG 233
Query: 221 LGIGSAIARTDFFPNGGNSQPGCSTSLCTTI 251
G+ + DFFPNGG PGC ++ +TI
Sbjct: 234 FGMSQKVGHLDFFPNGGKEMPGCKKNVLSTI 264
>M93285-1|AAA60129.1| 465|Homo sapiens lipase protein.
Length = 465
Score = 122 bits (295), Expect = 1e-27
Identities = 70/210 (33%), Positives = 92/210 (43%), Gaps = 7/210 (3%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPNPTIRNAFLN 107
++ L+T N Q V T I+HG++ +
Sbjct: 54 RFLLYTNENPNNFQE-VAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFK 112
Query: 108 KADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGA 167
VN I VDW SR+ YT F+ FL A G + SN+H+ G SLGA
Sbjct: 113 VESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGA 172
Query: 168 HVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGS----TSGL 221
H G AGR G + RITGLDPA P + RL P D +V+ IHTDG+ G
Sbjct: 173 HAAGEAGRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGF 232
Query: 222 GIGSAIARTDFFPNGGNSQPGCSTSLCTTI 251
G+ + DFFPNGG PGC ++ + I
Sbjct: 233 GMSQVVGHLDFFPNGGVEMPGCKKNILSQI 262
>L24529-1|AAA99053.1| 465|Homo sapiens pancreatic lipase protein.
Length = 465
Score = 122 bits (295), Expect = 1e-27
Identities = 70/210 (33%), Positives = 92/210 (43%), Gaps = 7/210 (3%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPNPTIRNAFLN 107
++ L+T N Q V T I+HG++ +
Sbjct: 54 RFLLYTNENPNNFQE-VAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFK 112
Query: 108 KADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGA 167
VN I VDW SR+ YT F+ FL A G + SN+H+ G SLGA
Sbjct: 113 VESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGA 172
Query: 168 HVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGS----TSGL 221
H G AGR G + RITGLDPA P + RL P D +V+ IHTDG+ G
Sbjct: 173 HAAGEAGRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGF 232
Query: 222 GIGSAIARTDFFPNGGNSQPGCSTSLCTTI 251
G+ + DFFPNGG PGC ++ + I
Sbjct: 233 GMSQVVGHLDFFPNGGVEMPGCKKNILSQI 262
>J05125-1|AAA36740.1| 465|Homo sapiens protein ( Human triglyceride
lipase mRNA, complete cds. ).
Length = 465
Score = 122 bits (295), Expect = 1e-27
Identities = 70/210 (33%), Positives = 92/210 (43%), Gaps = 7/210 (3%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPNPTIRNAFLN 107
++ L+T N Q V T I+HG++ +
Sbjct: 54 RFLLYTNENPNNFQE-VAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFK 112
Query: 108 KADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGA 167
VN I VDW SR+ YT F+ FL A G + SN+H+ G SLGA
Sbjct: 113 VESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGA 172
Query: 168 HVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGS----TSGL 221
H G AGR G + RITGLDPA P + RL P D +V+ IHTDG+ G
Sbjct: 173 HAAGEAGRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGF 232
Query: 222 GIGSAIARTDFFPNGGNSQPGCSTSLCTTI 251
G+ + DFFPNGG PGC ++ + I
Sbjct: 233 GMSQVVGHLDFFPNGGVEMPGCKKNILSQI 262
>BC014309-1|AAH14309.1| 465|Homo sapiens pancreatic lipase protein.
Length = 465
Score = 122 bits (295), Expect = 1e-27
Identities = 70/210 (33%), Positives = 92/210 (43%), Gaps = 7/210 (3%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPNPTIRNAFLN 107
++ L+T N Q V T I+HG++ +
Sbjct: 54 RFLLYTNENPNNFQE-VAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFK 112
Query: 108 KADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGA 167
VN I VDW SR+ YT F+ FL A G + SN+H+ G SLGA
Sbjct: 113 VESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGA 172
Query: 168 HVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGS----TSGL 221
H G AGR G + RITGLDPA P + RL P D +V+ IHTDG+ G
Sbjct: 173 HAAGEAGRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGF 232
Query: 222 GIGSAIARTDFFPNGGNSQPGCSTSLCTTI 251
G+ + DFFPNGG PGC ++ + I
Sbjct: 233 GMSQVVGHLDFFPNGGVEMPGCKKNILSQI 262
>AL731653-1|CAH72667.1| 465|Homo sapiens pancreatic lipase protein.
Length = 465
Score = 122 bits (295), Expect = 1e-27
Identities = 70/210 (33%), Positives = 92/210 (43%), Gaps = 7/210 (3%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPNPTIRNAFLN 107
++ L+T N Q V T I+HG++ +
Sbjct: 54 RFLLYTNENPNNFQE-VAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFK 112
Query: 108 KADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGA 167
VN I VDW SR+ YT F+ FL A G + SN+H+ G SLGA
Sbjct: 113 VESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGA 172
Query: 168 HVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGS----TSGL 221
H G AGR G + RITGLDPA P + RL P D +V+ IHTDG+ G
Sbjct: 173 HAAGEAGRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGF 232
Query: 222 GIGSAIARTDFFPNGGNSQPGCSTSLCTTI 251
G+ + DFFPNGG PGC ++ + I
Sbjct: 233 GMSQVVGHLDFFPNGGVEMPGCKKNILSQI 262
>U37591-1|AAC99994.1| 456|Homo sapiens nmd protein.
Length = 456
Score = 116 bits (280), Expect = 7e-26
Identities = 73/202 (36%), Positives = 98/202 (48%), Gaps = 10/202 (4%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPN--PTIRNAF 105
Q+ LF N Q ++ T +I+HG+ T+P+ T
Sbjct: 52 QFLLFVPSNPSCGQ--LVEGSSDLQNSGFNATLGTKLIIHGF-RVLGTKPSWIDTFIRTL 108
Query: 106 LNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSL 165
L + N+I+VDW Y S Y + FL L G + S++H+ G SL
Sbjct: 109 LRATNANVIAVDWIYGSTGVYFSAVKNVIKLSLEISLFLNKL-LVLGVSESSIHIIGVSL 167
Query: 166 GAHVVGNAGRELGGRVARITGLDPAGPLWNTNS--NRLRPGDGVYVEAIHTDGSTSGLGI 223
GAHV G G+ GG++ +ITGLDPAGP + S RL GD ++VEAIHTD T LGI
Sbjct: 168 GAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTD--TDNLGI 225
Query: 224 GSAIARTDFFPNGGNSQPGCST 245
+ D+F NGG QPGC T
Sbjct: 226 RIPVGHVDYFVNGGQDQPGCPT 247
>AF035269-1|AAC98922.1| 376|Homo sapiens
phosphatidylserine-specific phospholipase A1 deltaC
protein.
Length = 376
Score = 116 bits (280), Expect = 7e-26
Identities = 73/202 (36%), Positives = 98/202 (48%), Gaps = 10/202 (4%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPN--PTIRNAF 105
Q+ LF N Q ++ T +I+HG+ T+P+ T
Sbjct: 52 QFLLFVPSNPSCGQ--LVEGSSDLQNSGFNATLGTKLIIHGF-RVLGTKPSWIDTFIRTL 108
Query: 106 LNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSL 165
L + N+I+VDW Y S Y + FL L G + S++H+ G SL
Sbjct: 109 LRATNANVIAVDWIYGSTGVYFSAVKNVIKLSLEISLFLNKL-LVLGVSESSIHIIGVSL 167
Query: 166 GAHVVGNAGRELGGRVARITGLDPAGPLWNTNS--NRLRPGDGVYVEAIHTDGSTSGLGI 223
GAHV G G+ GG++ +ITGLDPAGP + S RL GD ++VEAIHTD T LGI
Sbjct: 168 GAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTD--TDNLGI 225
Query: 224 GSAIARTDFFPNGGNSQPGCST 245
+ D+F NGG QPGC T
Sbjct: 226 RIPVGHVDYFVNGGQDQPGCPT 247
>AF035268-1|AAC98921.1| 456|Homo sapiens
phosphatidylserine-specific phospholipase A1 protein.
Length = 456
Score = 116 bits (280), Expect = 7e-26
Identities = 73/202 (36%), Positives = 98/202 (48%), Gaps = 10/202 (4%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPN--PTIRNAF 105
Q+ LF N Q ++ T +I+HG+ T+P+ T
Sbjct: 52 QFLLFVPSNPSCGQ--LVEGSSDLQNSGFNATLGTKLIIHGF-RVLGTKPSWIDTFIRTL 108
Query: 106 LNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSL 165
L + N+I+VDW Y S Y + FL L G + S++H+ G SL
Sbjct: 109 LRATNANVIAVDWIYGSTGVYFSAVKNVIKLSLEISLFLNKL-LVLGVSESSIHIIGVSL 167
Query: 166 GAHVVGNAGRELGGRVARITGLDPAGPLWNTNS--NRLRPGDGVYVEAIHTDGSTSGLGI 223
GAHV G G+ GG++ +ITGLDPAGP + S RL GD ++VEAIHTD T LGI
Sbjct: 168 GAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTD--TDNLGI 225
Query: 224 GSAIARTDFFPNGGNSQPGCST 245
+ D+F NGG QPGC T
Sbjct: 226 RIPVGHVDYFVNGGQDQPGCPT 247
>AK222705-1|BAD96425.1| 456|Homo sapiens phospholipase A1 member A
variant protein.
Length = 456
Score = 115 bits (276), Expect = 2e-25
Identities = 72/202 (35%), Positives = 97/202 (48%), Gaps = 10/202 (4%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPN--PTIRNAF 105
Q+ LF N Q ++ T +I+HG+ T+P+ T
Sbjct: 52 QFLLFVPSNPSCGQ--LVEGSSDLQNSGFNATLGTKLIIHGF-RVLGTKPSWIDTFIRTL 108
Query: 106 LNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSL 165
L + N+I+VDW Y S Y + FL L G + S++H+ G SL
Sbjct: 109 LRATNANVIAVDWIYGSTGVYFSAVKNVIKLSLEISLFLNKL-LVLGVSESSIHIIGVSL 167
Query: 166 GAHVVGNAGRELGGRVARITGLDPAGPLWNTNS--NRLRPGDGVYVEAIHTDGSTSGLGI 223
GAHV G G+ GG++ +ITGLDPAGP + S RL GD ++ EAIHTD T LGI
Sbjct: 168 GAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDALFTEAIHTD--TDNLGI 225
Query: 224 GSAIARTDFFPNGGNSQPGCST 245
+ D+F NGG QPGC T
Sbjct: 226 RIPVGHVDYFVNGGQDQPGCPT 247
>BC060825-1|AAH60825.1| 500|Homo sapiens lipase, endothelial
protein.
Length = 500
Score = 113 bits (272), Expect = 7e-25
Identities = 61/168 (36%), Positives = 85/168 (50%), Gaps = 6/168 (3%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T I+HGW + E + + + D N++ VDW L+ YT
Sbjct: 85 TFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHS 144
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWNTNS- 198
+ L +L + + N+HL G+SLGAHV G AG + G V RITGLDPAGP++
Sbjct: 145 IARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADI 204
Query: 199 -NRLRPGDGVYVEAIHTDGSTSGLGIG--SAIARTDFFPNGGNSQPGC 243
RL P D +V+ +HT + GL IG + D +PNGG+ QPGC
Sbjct: 205 HKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGC 252
>AY358928-1|AAQ89287.1| 354|Homo sapiens lipoprotein lipase H
protein.
Length = 354
Score = 113 bits (272), Expect = 7e-25
Identities = 61/168 (36%), Positives = 85/168 (50%), Gaps = 6/168 (3%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T I+HGW + E + + + D N++ VDW L+ YT
Sbjct: 85 TFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHS 144
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWNTNS- 198
+ L +L + + N+HL G+SLGAHV G AG + G V RITGLDPAGP++
Sbjct: 145 IARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADI 204
Query: 199 -NRLRPGDGVYVEAIHTDGSTSGLGIG--SAIARTDFFPNGGNSQPGC 243
RL P D +V+ +HT + GL IG + D +PNGG+ QPGC
Sbjct: 205 HKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGC 252
>AK125344-1|BAC86139.1| 390|Homo sapiens protein ( Homo sapiens
cDNA FLJ43354 fis, clone NT2RP7010599, highly similar
to Homo sapiens endothelial lipase mRNA. ).
Length = 390
Score = 113 bits (272), Expect = 7e-25
Identities = 61/168 (36%), Positives = 85/168 (50%), Gaps = 6/168 (3%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T I+HGW + E + + + D N++ VDW L+ YT
Sbjct: 121 TFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHS 180
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWNTNS- 198
+ L +L + + N+HL G+SLGAHV G AG + G V RITGLDPAGP++
Sbjct: 181 IARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADI 240
Query: 199 -NRLRPGDGVYVEAIHTDGSTSGLGIG--SAIARTDFFPNGGNSQPGC 243
RL P D +V+ +HT + GL IG + D +PNGG+ QPGC
Sbjct: 241 HKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGC 288
>AF118767-1|AAD30434.1| 500|Homo sapiens endothelial lipase
protein.
Length = 500
Score = 113 bits (272), Expect = 7e-25
Identities = 61/168 (36%), Positives = 85/168 (50%), Gaps = 6/168 (3%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T I+HGW + E + + + D N++ VDW L+ YT
Sbjct: 85 TFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHS 144
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWNTNS- 198
+ L +L + + N+HL G+SLGAHV G AG + G V RITGLDPAGP++
Sbjct: 145 IARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADI 204
Query: 199 -NRLRPGDGVYVEAIHTDGSTSGLGIG--SAIARTDFFPNGGNSQPGC 243
RL P D +V+ +HT + GL IG + D +PNGG+ QPGC
Sbjct: 205 HKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGC 252
>M35433-1|AAA59521.1| 499|Homo sapiens hepatic lipase protein.
Length = 499
Score = 111 bits (267), Expect = 3e-24
Identities = 68/174 (39%), Positives = 92/174 (52%), Gaps = 12/174 (6%)
Query: 81 PTVVIVHGWLSTRNTEPNPTIRNAFLNKAD----VNIISVDWSYLSRSDYTTXXXXXXXX 136
P V+I+HGW S N + K+ VN+ VDW L+ YT
Sbjct: 82 PLVMIIHGW-SVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLV 140
Query: 137 XXXXXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGG--RVARITGLDPAGPLW 194
L +L ++ + S++HL G+SLGAHV G AG +GG ++ RITGLD AGPL+
Sbjct: 141 GKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLF 200
Query: 195 --NTNSNRLRPGDGVYVEAIHT---DGSTSGLGIGSAIARTDFFPNGGNSQPGC 243
+ SNRL P D +V+AIHT + +GI I DF+PNGG+ QPGC
Sbjct: 201 EGSAPSNRLSPDDASFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGC 254
>J03540-1|AAA59520.1| 499|Homo sapiens LIPC protein.
Length = 499
Score = 111 bits (267), Expect = 3e-24
Identities = 68/174 (39%), Positives = 92/174 (52%), Gaps = 12/174 (6%)
Query: 81 PTVVIVHGWLSTRNTEPNPTIRNAFLNKAD----VNIISVDWSYLSRSDYTTXXXXXXXX 136
P V+I+HGW S N + K+ VN+ VDW L+ YT
Sbjct: 82 PLVMIIHGW-SVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLV 140
Query: 137 XXXXXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGG--RVARITGLDPAGPLW 194
L +L ++ + S++HL G+SLGAHV G AG +GG ++ RITGLD AGPL+
Sbjct: 141 GKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLF 200
Query: 195 --NTNSNRLRPGDGVYVEAIHT---DGSTSGLGIGSAIARTDFFPNGGNSQPGC 243
+ SNRL P D +V+AIHT + +GI I DF+PNGG+ QPGC
Sbjct: 201 EGSAPSNRLSPDDASFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGC 254
>D83548-1|BAA12014.1| 499|Homo sapiens hepatic triglyceride lipase
protein.
Length = 499
Score = 111 bits (267), Expect = 3e-24
Identities = 68/174 (39%), Positives = 92/174 (52%), Gaps = 12/174 (6%)
Query: 81 PTVVIVHGWLSTRNTEPNPTIRNAFLNKAD----VNIISVDWSYLSRSDYTTXXXXXXXX 136
P V+I+HGW S N + K+ VN+ VDW L+ YT
Sbjct: 82 PLVMIIHGW-SVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLV 140
Query: 137 XXXXXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGG--RVARITGLDPAGPLW 194
L +L ++ + S++HL G+SLGAHV G AG +GG ++ RITGLD AGPL+
Sbjct: 141 GKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLF 200
Query: 195 --NTNSNRLRPGDGVYVEAIHT---DGSTSGLGIGSAIARTDFFPNGGNSQPGC 243
+ SNRL P D +V+AIHT + +GI I DF+PNGG+ QPGC
Sbjct: 201 EGSAPSNRLSPDDASFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGC 254
>X07228-1|CAA30188.1| 499|Homo sapiens protein ( Human mRNA for
hepatic triglyceride lipase (HTGL). ).
Length = 499
Score = 111 bits (266), Expect = 4e-24
Identities = 68/174 (39%), Positives = 92/174 (52%), Gaps = 12/174 (6%)
Query: 81 PTVVIVHGWLSTRNTEPNPTIRNAFLNKAD----VNIISVDWSYLSRSDYTTXXXXXXXX 136
P V+I+HGW S N + K+ VN+ VDW L+ YT
Sbjct: 82 PLVMIIHGW-SVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLV 140
Query: 137 XXXXXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGG--RVARITGLDPAGPLW 194
L +L ++ + S++HL G+SLGAHV G AG +GG ++ RITGLD AGPL+
Sbjct: 141 GKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLF 200
Query: 195 --NTNSNRLRPGDGVYVEAIHT---DGSTSGLGIGSAIARTDFFPNGGNSQPGC 243
+ SNRL P D +V+AIHT + +GI I DF+PNGG+ QPGC
Sbjct: 201 EGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGC 254
>M29194-1|AAB60702.1| 499|Homo sapiens protein ( Human triglyceride
lipase gene, exon 9. ).
Length = 499
Score = 111 bits (266), Expect = 4e-24
Identities = 68/174 (39%), Positives = 92/174 (52%), Gaps = 12/174 (6%)
Query: 81 PTVVIVHGWLSTRNTEPNPTIRNAFLNKAD----VNIISVDWSYLSRSDYTTXXXXXXXX 136
P V+I+HGW S N + K+ VN+ VDW L+ YT
Sbjct: 82 PLVMIIHGW-SVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLV 140
Query: 137 XXXXXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGG--RVARITGLDPAGPLW 194
L +L ++ + S++HL G+SLGAHV G AG +GG ++ RITGLD AGPL+
Sbjct: 141 GKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLF 200
Query: 195 --NTNSNRLRPGDGVYVEAIHT---DGSTSGLGIGSAIARTDFFPNGGNSQPGC 243
+ SNRL P D +V+AIHT + +GI I DF+PNGG+ QPGC
Sbjct: 201 EGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGC 254
>J03895-1|AAA61165.1| 499|Homo sapiens LIPC protein.
Length = 499
Score = 111 bits (266), Expect = 4e-24
Identities = 68/174 (39%), Positives = 92/174 (52%), Gaps = 12/174 (6%)
Query: 81 PTVVIVHGWLSTRNTEPNPTIRNAFLNKAD----VNIISVDWSYLSRSDYTTXXXXXXXX 136
P V+I+HGW S N + K+ VN+ VDW L+ YT
Sbjct: 82 PLVMIIHGW-SVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLV 140
Query: 137 XXXXXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGG--RVARITGLDPAGPLW 194
L +L ++ + S++HL G+SLGAHV G AG +GG ++ RITGLD AGPL+
Sbjct: 141 GKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLF 200
Query: 195 --NTNSNRLRPGDGVYVEAIHT---DGSTSGLGIGSAIARTDFFPNGGNSQPGC 243
+ SNRL P D +V+AIHT + +GI I DF+PNGG+ QPGC
Sbjct: 201 EGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGC 254
>BC132825-1|AAI32826.1| 499|Homo sapiens lipase, hepatic protein.
Length = 499
Score = 111 bits (266), Expect = 4e-24
Identities = 68/174 (39%), Positives = 92/174 (52%), Gaps = 12/174 (6%)
Query: 81 PTVVIVHGWLSTRNTEPNPTIRNAFLNKAD----VNIISVDWSYLSRSDYTTXXXXXXXX 136
P V+I+HGW S N + K+ VN+ VDW L+ YT
Sbjct: 82 PLVMIIHGW-SVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLV 140
Query: 137 XXXXXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGG--RVARITGLDPAGPLW 194
L +L ++ + S++HL G+SLGAHV G AG +GG ++ RITGLD AGPL+
Sbjct: 141 GKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLF 200
Query: 195 --NTNSNRLRPGDGVYVEAIHT---DGSTSGLGIGSAIARTDFFPNGGNSQPGC 243
+ SNRL P D +V+AIHT + +GI I DF+PNGG+ QPGC
Sbjct: 201 EGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGC 254
>EF186229-1|ABM67095.1| 451|Homo sapiens lipase H protein.
Length = 451
Score = 107 bits (258), Expect = 3e-23
Identities = 66/201 (32%), Positives = 100/201 (49%), Gaps = 12/201 (5%)
Query: 51 LFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEP-NPTIRNAFLNKA 109
L+TR+N +QT+ T IVHG+ T + + L+
Sbjct: 45 LYTRKNLTCAQTI-----NSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVE 99
Query: 110 DVNIISVDWSYLSRS-DYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGAH 168
D+N++ VDW+ + + YT +F+ + A GA+ ++++ G SLGAH
Sbjct: 100 DMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQM-LAEGASLDDIYMIGVSLGAH 158
Query: 169 VVGNAGRELGGRVARITGLDPAGPLWN--TNSNRLRPGDGVYVEAIHTDGSTSGLGIGSA 226
+ G G G + RITGLDPAGPL+N + +RL P D +V+ IH+D T LG
Sbjct: 159 ISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSD--TDALGYKEP 216
Query: 227 IARTDFFPNGGNSQPGCSTSL 247
+ DF+PNGG QPGC ++
Sbjct: 217 LGNIDFYPNGGLDQPGCPKTI 237
>BC064941-1|AAH64941.1| 451|Homo sapiens lipase, member H protein.
Length = 451
Score = 107 bits (258), Expect = 3e-23
Identities = 66/201 (32%), Positives = 100/201 (49%), Gaps = 12/201 (5%)
Query: 51 LFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEP-NPTIRNAFLNKA 109
L+TR+N +QT+ T IVHG+ T + + L+
Sbjct: 45 LYTRKNLTCAQTI-----NSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVE 99
Query: 110 DVNIISVDWSYLSRS-DYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGAH 168
D+N++ VDW+ + + YT +F+ + A GA+ ++++ G SLGAH
Sbjct: 100 DMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQM-LAEGASLDDIYMIGVSLGAH 158
Query: 169 VVGNAGRELGGRVARITGLDPAGPLWN--TNSNRLRPGDGVYVEAIHTDGSTSGLGIGSA 226
+ G G G + RITGLDPAGPL+N + +RL P D +V+ IH+D T LG
Sbjct: 159 ISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSD--TDALGYKEP 216
Query: 227 IARTDFFPNGGNSQPGCSTSL 247
+ DF+PNGG QPGC ++
Sbjct: 217 LGNIDFYPNGGLDQPGCPKTI 237
>AY093498-1|AAM18803.1| 451|Homo sapiens lipase H protein.
Length = 451
Score = 107 bits (258), Expect = 3e-23
Identities = 66/201 (32%), Positives = 100/201 (49%), Gaps = 12/201 (5%)
Query: 51 LFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEP-NPTIRNAFLNKA 109
L+TR+N +QT+ T IVHG+ T + + L+
Sbjct: 45 LYTRKNLTCAQTI-----NSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVE 99
Query: 110 DVNIISVDWSYLSRS-DYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGAH 168
D+N++ VDW+ + + YT +F+ + A GA+ ++++ G SLGAH
Sbjct: 100 DMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQM-LAEGASLDDIYMIGVSLGAH 158
Query: 169 VVGNAGRELGGRVARITGLDPAGPLWN--TNSNRLRPGDGVYVEAIHTDGSTSGLGIGSA 226
+ G G G + RITGLDPAGPL+N + +RL P D +V+ IH+D T LG
Sbjct: 159 ISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSD--TDALGYKEP 216
Query: 227 IARTDFFPNGGNSQPGCSTSL 247
+ DF+PNGG QPGC ++
Sbjct: 217 LGNIDFYPNGGLDQPGCPKTI 237
>AY036912-1|AAK63178.1| 451|Homo sapiens membrane-bound
phosphatidic acid-selective phospholipase A1 protein.
Length = 451
Score = 107 bits (258), Expect = 3e-23
Identities = 66/201 (32%), Positives = 100/201 (49%), Gaps = 12/201 (5%)
Query: 51 LFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEP-NPTIRNAFLNKA 109
L+TR+N +QT+ T IVHG+ T + + L+
Sbjct: 45 LYTRKNLTCAQTI-----NSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVE 99
Query: 110 DVNIISVDWSYLSRS-DYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGAH 168
D+N++ VDW+ + + YT +F+ + A GA+ ++++ G SLGAH
Sbjct: 100 DMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQM-LAEGASLDDIYMIGVSLGAH 158
Query: 169 VVGNAGRELGGRVARITGLDPAGPLWN--TNSNRLRPGDGVYVEAIHTDGSTSGLGIGSA 226
+ G G G + RITGLDPAGPL+N + +RL P D +V+ IH+D T LG
Sbjct: 159 ISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSD--TDALGYKEP 216
Query: 227 IARTDFFPNGGNSQPGCSTSL 247
+ DF+PNGG QPGC ++
Sbjct: 217 LGNIDFYPNGGLDQPGCPKTI 237
>CR457054-1|CAG33335.1| 475|Homo sapiens LPL protein.
Length = 475
Score = 105 bits (253), Expect = 1e-22
Identities = 57/170 (33%), Positives = 84/170 (49%), Gaps = 7/170 (4%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T +++HGW T E + + + + D N+I VDW ++ Y
Sbjct: 75 TFMVIHGWTVTGMYESWVSKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQD 134
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWN--TN 197
+F+ ++ + N+HL G+SLGAH G AG +V RITGLDPAGP +
Sbjct: 135 VARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEA 194
Query: 198 SNRLRPGDGVYVEAIH--TDGSTS-GLGIGSAIARTDFFPNGGNSQPGCS 244
+RL P D +V+ +H T GS +GI + D +PNGG QPGC+
Sbjct: 195 PSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCN 244
>BC047703-1|AAH47703.1| 440|Homo sapiens PLA1A protein protein.
Length = 440
Score = 105 bits (252), Expect = 2e-22
Identities = 70/202 (34%), Positives = 96/202 (47%), Gaps = 26/202 (12%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPN--PTIRNAF 105
Q+ LF N Q ++ T +I+HG+ T+P+ T
Sbjct: 52 QFLLFVPSNPSCGQ--LVEGSSDLQNSGFNATLGTKLIIHGF-RVLGTKPSWIDTFIRTL 108
Query: 106 LNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSL 165
L + N+I+VDW Y S Y + + G + S++H+ G SL
Sbjct: 109 LRATNANVIAVDWIYGSTGVYFSA-----------------VKNVLGVSESSIHIIGVSL 151
Query: 166 GAHVVGNAGRELGGRVARITGLDPAGPLWNTNS--NRLRPGDGVYVEAIHTDGSTSGLGI 223
GAHV G G+ GG++ +ITGLDPAGP + S RL GD ++VEAIHTD T LGI
Sbjct: 152 GAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTD--TDNLGI 209
Query: 224 GSAIARTDFFPNGGNSQPGCST 245
+ D+F NGG QPGC T
Sbjct: 210 RIPVGHVDYFVNGGQDQPGCPT 231
>X54516-1|CAA38372.1| 475|Homo sapiens protein ( Human mRNA for
lipoprotein lipase (EC 3.1.1.34). ).
Length = 475
Score = 104 bits (250), Expect = 3e-22
Identities = 57/170 (33%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T +++HGW T E + + + D N+I VDW ++ Y
Sbjct: 75 TFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQD 134
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWN--TN 197
+F+ ++ + N+HL G+SLGAH G AG +V RITGLDPAGP +
Sbjct: 135 VARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEA 194
Query: 198 SNRLRPGDGVYVEAIH--TDGSTS-GLGIGSAIARTDFFPNGGNSQPGCS 244
+RL P D +V+ +H T GS +GI + D +PNGG QPGC+
Sbjct: 195 PSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCN 244
>X14390-1|CAA32564.1| 475|Homo sapiens protein ( Human mRNA for
lipoprotein lipase (EC 3.1.1.34). ).
Length = 475
Score = 104 bits (250), Expect = 3e-22
Identities = 57/170 (33%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T +++HGW T E + + + D N+I VDW ++ Y
Sbjct: 75 TFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQD 134
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWN--TN 197
+F+ ++ + N+HL G+SLGAH G AG +V RITGLDPAGP +
Sbjct: 135 VARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEA 194
Query: 198 SNRLRPGDGVYVEAIH--TDGSTS-GLGIGSAIARTDFFPNGGNSQPGCS 244
+RL P D +V+ +H T GS +GI + D +PNGG QPGC+
Sbjct: 195 PSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCN 244
>M15856-1|AAB59536.1| 475|Homo sapiens LPL protein.
Length = 475
Score = 104 bits (250), Expect = 3e-22
Identities = 57/170 (33%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T +++HGW T E + + + D N+I VDW ++ Y
Sbjct: 75 TFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQD 134
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWN--TN 197
+F+ ++ + N+HL G+SLGAH G AG +V RITGLDPAGP +
Sbjct: 135 VARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEA 194
Query: 198 SNRLRPGDGVYVEAIH--TDGSTS-GLGIGSAIARTDFFPNGGNSQPGCS 244
+RL P D +V+ +H T GS +GI + D +PNGG QPGC+
Sbjct: 195 PSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCN 244
>BT006726-1|AAP35372.1| 475|Homo sapiens lipoprotein lipase
protein.
Length = 475
Score = 104 bits (250), Expect = 3e-22
Identities = 57/170 (33%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T +++HGW T E + + + D N+I VDW ++ Y
Sbjct: 75 TFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQD 134
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWN--TN 197
+F+ ++ + N+HL G+SLGAH G AG +V RITGLDPAGP +
Sbjct: 135 VARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEA 194
Query: 198 SNRLRPGDGVYVEAIH--TDGSTS-GLGIGSAIARTDFFPNGGNSQPGCS 244
+RL P D +V+ +H T GS +GI + D +PNGG QPGC+
Sbjct: 195 PSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCN 244
>BC011353-1|AAH11353.1| 475|Homo sapiens lipoprotein lipase
protein.
Length = 475
Score = 104 bits (250), Expect = 3e-22
Identities = 57/170 (33%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T +++HGW T E + + + D N+I VDW ++ Y
Sbjct: 75 TFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQD 134
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWN--TN 197
+F+ ++ + N+HL G+SLGAH G AG +V RITGLDPAGP +
Sbjct: 135 VARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEA 194
Query: 198 SNRLRPGDGVYVEAIH--TDGSTS-GLGIGSAIARTDFFPNGGNSQPGCS 244
+RL P D +V+ +H T GS +GI + D +PNGG QPGC+
Sbjct: 195 PSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCN 244
>AK222464-1|BAD96184.1| 475|Homo sapiens lipoprotein lipase
precursor variant protein.
Length = 475
Score = 104 bits (250), Expect = 3e-22
Identities = 57/170 (33%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 82 TVVIVHGWLSTRNTEP--NPTIRNAFLNKADVNIISVDWSYLSRSDYTTXXXXXXXXXXX 139
T +++HGW T E + + + D N+I VDW ++ Y
Sbjct: 75 TFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQD 134
Query: 140 XXQFLTFLNQATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWN--TN 197
+F+ ++ + N+HL G+SLGAH G AG +V RITGLDPAGP +
Sbjct: 135 VARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEA 194
Query: 198 SNRLRPGDGVYVEAIH--TDGSTS-GLGIGSAIARTDFFPNGGNSQPGCS 244
+RL P D +V+ +H T GS +GI + D +PNGG QPGC+
Sbjct: 195 PSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCN 244
>M93283-1|AAA59532.1| 467|Homo sapiens lipase related protein 1
protein.
Length = 467
Score = 104 bits (249), Expect = 4e-22
Identities = 65/210 (30%), Positives = 90/210 (42%), Gaps = 7/210 (3%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPNPTIRNAFLN 107
++ L+T N Q L++ T I+HG++ + +
Sbjct: 55 RFLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFE 114
Query: 108 KADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGA 167
+VN I VDW S++ YT Q L L S +HL G SLGA
Sbjct: 115 VEEVNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGA 174
Query: 168 HVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGST----SGL 221
HV G AG + G ++RITGLDP + + RL P D +V+ IHTD + G
Sbjct: 175 HVAGEAGSKTPG-LSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGF 233
Query: 222 GIGSAIARTDFFPNGGNSQPGCSTSLCTTI 251
G + DFFPNGG S PGC + + I
Sbjct: 234 GTNQQMGHLDFFPNGGESMPGCKKNALSQI 263
>BC025784-1|AAH25784.1| 467|Homo sapiens pancreatic lipase-related
protein 1 protein.
Length = 467
Score = 104 bits (249), Expect = 4e-22
Identities = 65/210 (30%), Positives = 90/210 (42%), Gaps = 7/210 (3%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPNPTIRNAFLN 107
++ L+T N Q L++ T I+HG++ + +
Sbjct: 55 RFLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFE 114
Query: 108 KADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGA 167
+VN I VDW S++ YT Q L L S +HL G SLGA
Sbjct: 115 VEEVNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGA 174
Query: 168 HVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGST----SGL 221
HV G AG + G ++RITGLDP + + RL P D +V+ IHTD + G
Sbjct: 175 HVAGEAGSKTPG-LSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGF 233
Query: 222 GIGSAIARTDFFPNGGNSQPGCSTSLCTTI 251
G + DFFPNGG S PGC + + I
Sbjct: 234 GTNQQMGHLDFFPNGGESMPGCKKNALSQI 263
>AY197607-1|AAP37476.1| 481|Homo sapiens membrane-associated
phospholipase A1 beta protein.
Length = 481
Score = 103 bits (247), Expect = 7e-22
Identities = 58/150 (38%), Positives = 83/150 (55%), Gaps = 6/150 (4%)
Query: 106 LNKADVNIISVDWSYLSRSD-YTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFS 164
LN+ D+N+I VDWS + + Y + L + GA+ N H G S
Sbjct: 122 LNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKH-GASLDNFHFIGVS 180
Query: 165 LGAHVVGNAGRELGGRVARITGLDPAGPLWNTNS--NRLRPGDGVYVEAIHTDGSTSGLG 222
LGAH+ G G+ G++ RITGLDPAGP ++ +RL D +V+ IH+D ++GLG
Sbjct: 181 LGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSD--SNGLG 238
Query: 223 IGSAIARTDFFPNGGNSQPGCSTSLCTTIE 252
I + DF+PNGGN QPGC S+ + I+
Sbjct: 239 IQEPLGHIDFYPNGGNKQPGCPKSIFSGIQ 268
>BC117224-1|AAI17225.1| 467|Homo sapiens pancreatic lipase-related
protein 3 protein.
Length = 467
Score = 99.5 bits (237), Expect = 1e-20
Identities = 64/202 (31%), Positives = 94/202 (46%), Gaps = 10/202 (4%)
Query: 48 QYFLFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEPNPTIRNAFLN 107
++ L+T N A Q + T + + GW + + + + N L
Sbjct: 55 RFLLYTIHNPNAYQEISAVNSSTIQASYFGTDKITRINIAGWKTDGKWQRD--MCNVLLQ 112
Query: 108 KADVNIISVDWSYLSRSDYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGA 167
D+N I++DW SR +Y F+ L + + S +HL G SLGA
Sbjct: 113 LEDINCINLDWINGSR-EYIHAVNNLRVVGAEVAYFIDVLMKKFEYSPSKVHLIGHSLGA 171
Query: 168 HVVGNAGRELGGRVARITGLDPAGPLWNTNSN--RLRPGDGVYVEAIHTDGSTS--GLGI 223
H+ G AG + G + RITGLDPAGP ++ RL P D +V+ IHT+ + LG+
Sbjct: 172 HLAGEAGSRIPG-LGRITGLDPAGPFFHNTPKEVRLDPSDANFVDVIHTNAARILFELGV 230
Query: 224 GS--AIARTDFFPNGGNSQPGC 243
G+ A DF+PNGG PGC
Sbjct: 231 GTIDACGHLDFYPNGGKHMPGC 252
>AK074229-1|BAB85023.1| 323|Homo sapiens protein ( Homo sapiens
cDNA FLJ23649 fis, clone COL06395, highly similar to
Oryctolagus cuniculus lacrimal lipase mRNA. ).
Length = 323
Score = 94.3 bits (224), Expect = 5e-19
Identities = 47/106 (44%), Positives = 66/106 (62%), Gaps = 6/106 (5%)
Query: 146 FLNQ--ATGAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWN--TNSNRL 201
F++Q A GA+ ++++ G SLGAH+ G G G + RITGLDPAGPL+N + +RL
Sbjct: 6 FIDQMLAEGASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRL 65
Query: 202 RPGDGVYVEAIHTDGSTSGLGIGSAIARTDFFPNGGNSQPGCSTSL 247
P D +V+ IH+D T LG + DF+PNGG QPGC ++
Sbjct: 66 DPSDAQFVDVIHSD--TDALGYKEPLGNIDFYPNGGLDQPGCPKTI 109
>AF050163-1|AAC61679.1| 332|Homo sapiens lipoprotein lipase
precursor protein.
Length = 332
Score = 82.6 bits (195), Expect = 1e-15
Identities = 43/93 (46%), Positives = 55/93 (59%), Gaps = 5/93 (5%)
Query: 157 NMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWN--TNSNRLRPGDGVYVEAIH- 213
N+HL G+SLGAH G AG +V RITGLDPAGP + +RL P D +V+ +H
Sbjct: 9 NVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHT 68
Query: 214 -TDGSTS-GLGIGSAIARTDFFPNGGNSQPGCS 244
T GS +GI + D +PNGG QPGC+
Sbjct: 69 FTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCN 101
>AY918476-1|AAX14040.1| 140|Homo sapiens membrane-associated
phospholipase A1 beta splice variant protein.
Length = 140
Score = 62.5 bits (145), Expect = 2e-09
Identities = 30/68 (44%), Positives = 42/68 (61%), Gaps = 2/68 (2%)
Query: 152 GAAFSNMHLAGFSLGAHVVGNAGRELGGRVARITGLDPAGPLWNTNS--NRLRPGDGVYV 209
GA+ N H G SLGAH+ G G+ G++ RITGLDPAGP ++ +RL D +V
Sbjct: 26 GASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFV 85
Query: 210 EAIHTDGS 217
+ IH+D +
Sbjct: 86 DVIHSDSN 93
>EF186228-1|ABM67094.1| 417|Homo sapiens mutant lipase H protein.
Length = 417
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 8/147 (5%)
Query: 51 LFTRRNARASQTLVMXXXXXXXXXXXXXXXPTVVIVHGWLSTRNTEP-NPTIRNAFLNKA 109
L+TR+N +QT+ T IVHG+ T + + L+
Sbjct: 45 LYTRKNLTCAQTI-----NSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVE 99
Query: 110 DVNIISVDWSYLSRS-DYTTXXXXXXXXXXXXXQFLTFLNQATGAAFSNMHLAGFSLGAH 168
D+N++ VDW+ + + YT +F+ + A GA+ ++++ G SLGAH
Sbjct: 100 DMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQM-LAEGASLDDIYMIGVSLGAH 158
Query: 169 VVGNAGRELGGRVARITGLDPAGPLWN 195
+ G G G + RIT L PL N
Sbjct: 159 ISGFVGEMYDGWLGRITALGYKEPLGN 185
Score = 35.1 bits (77), Expect = 0.29
Identities = 13/32 (40%), Positives = 18/32 (56%)
Query: 216 GSTSGLGIGSAIARTDFFPNGGNSQPGCSTSL 247
G + LG + DF+PNGG QPGC ++
Sbjct: 172 GRITALGYKEPLGNIDFYPNGGLDQPGCPKTI 203
>EF186230-1|ABM67096.1| 33|Homo sapiens lipase H protein.
Length = 33
Score = 35.9 bits (79), Expect = 0.17
Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 2/31 (6%)
Query: 187 LDPAGPLWN--TNSNRLRPGDGVYVEAIHTD 215
LDPAGPL+N + +RL P D +V+ IH+D
Sbjct: 1 LDPAGPLFNGKPHQDRLDPSDAQFVDVIHSD 31
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.134 0.411
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 41,473,888
Number of Sequences: 224733
Number of extensions: 1592780
Number of successful extensions: 5484
Number of sequences better than 10.0: 44
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 5327
Number of HSP's gapped (non-prelim): 46
length of query: 293
length of database: 73,234,838
effective HSP length: 89
effective length of query: 204
effective length of database: 53,233,601
effective search space: 10859654604
effective search space used: 10859654604
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 65 (30.3 bits)
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