Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001502-TA|BGIBMGA001502-PA|IPR008930|Terpenoid
cylases/protein prenyltransferase alpha-alpha toroid,
IPR001330|Prenyltransferase/squalene oxidase
(268 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L25441-1|AAA35888.1| 377|Homo sapiens geranylgeranyltransferase... 275 9e-74
AY780790-1|AAV98360.1| 300|Homo sapiens geranylgeranyltransfera... 124 3e-28
X98001-1|CAA66638.1| 331|Homo sapiens geranylgeranyl transferas... 114 3e-25
U49245-1|AAA91473.1| 331|Homo sapiens geranylgeranyl transferas... 114 3e-25
CR456941-1|CAG33222.1| 331|Homo sapiens RABGGTB protein. 114 3e-25
BC020790-1|AAH20790.1| 331|Homo sapiens Rab geranylgeranyltrans... 114 3e-25
AL357314-5|CAI22393.1| 331|Homo sapiens Rab geranylgeranyltrans... 114 3e-25
Y08201-1|CAA69383.1| 331|Homo sapiens rab geranylgeranyl transf... 112 1e-24
AB209023-1|BAD92260.1| 320|Homo sapiens Rab geranylgeranyltrans... 105 2e-22
L10414-1|AAA86286.1| 387|Homo sapiens farnesyl-protein transfer... 83 1e-15
L00635-1|AAA35854.1| 437|Homo sapiens farnesyl-protein transfer... 83 1e-15
BC020232-1|AAH20232.1| 437|Homo sapiens farnesyltransferase, CA... 83 1e-15
>L25441-1|AAA35888.1| 377|Homo sapiens geranylgeranyltransferase
type I beta-subunit protein.
Length = 377
Score = 275 bits (675), Expect = 9e-74
Identities = 126/272 (46%), Positives = 175/272 (64%), Gaps = 6/272 (2%)
Query: 1 MSLCGFQGSSTINIRLDPDN-----NQFRCGHLAMTYTGLCILLALGDDLSRINRTALIQ 55
++ CGF+GSS + I +P + + GH+AMTYTGL L+ LGDDLSR+N+ A +
Sbjct: 90 LNRCGFRGSSYLGIPFNPSKAPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLA 149
Query: 56 GVKALQTDEGNFSATLSGCESDMRFVYCAACISYILNDWSGFDIEKATDYVIKSIGYDYG 115
G++ALQ ++G+F A G E+DMRFVYCA+CI Y+LN+WSG D++KA Y+ +S+ YD G
Sbjct: 150 GLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAITYIRRSMSYDNG 209
Query: 116 IAQCPELESHGGXXXXXXXXXXXXDQLDKL-SEAQIDGLKRWLVYRQIDGFQGRPNKPVD 174
+AQ LESHGG +L+++ SE +++ +KRW + RQ +G+ GRPNKPVD
Sbjct: 210 LAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVD 269
Query: 175 TCYSFWVGASLKILNALQLTNYGSNRRYVYETQDMVVGGFSKWPDTCTDPMHTYXXXXXX 234
TCYSFWVGA+LK+L Q TN+ NR Y+ TQD +VGGF+KWPD+ D +H Y
Sbjct: 270 TCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGL 329
Query: 235 XXXXXXXXXXXXPRLNITKRAYEHLKCLHEQW 266
P LN++ R E L LH+ W
Sbjct: 330 SLMEESGICKVHPALNVSTRTSERLLDLHQSW 361
>AY780790-1|AAV98360.1| 300|Homo sapiens geranylgeranyltransferase
type I beta subunit protein.
Length = 300
Score = 124 bits (299), Expect = 3e-28
Identities = 56/115 (48%), Positives = 82/115 (71%), Gaps = 5/115 (4%)
Query: 1 MSLCGFQGSSTINIRLDPDN-----NQFRCGHLAMTYTGLCILLALGDDLSRINRTALIQ 55
++ CGF+GSS + I +P + + GH+AMT TGL L+ LGDDLSR+N+ A +
Sbjct: 90 LNRCGFRGSSYLGIPFNPSKAPGTAHPYDSGHIAMTCTGLSCLVILGDDLSRVNKEACLA 149
Query: 56 GVKALQTDEGNFSATLSGCESDMRFVYCAACISYILNDWSGFDIEKATDYVIKSI 110
G++ALQ ++G+F A G E+DMRFVYCA+CI Y+LN+WSG D++KA Y+ +S+
Sbjct: 150 GLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAITYIRRSM 204
Score = 68.9 bits (161), Expect = 2e-11
Identities = 30/80 (37%), Positives = 40/80 (50%)
Query: 187 ILNALQLTNYGSNRRYVYETQDMVVGGFSKWPDTCTDPMHTYXXXXXXXXXXXXXXXXXX 246
+L Q TN+ NR Y+ TQD +VGGF+KWPD+ D +H Y
Sbjct: 205 LLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVH 264
Query: 247 PRLNITKRAYEHLKCLHEQW 266
P LN++ R E L LH+ W
Sbjct: 265 PALNVSTRTSERLLDLHQSW 284
>X98001-1|CAA66638.1| 331|Homo sapiens geranylgeranyl transferase
II protein.
Length = 331
Score = 114 bits (275), Expect = 3e-25
Identities = 69/203 (33%), Positives = 101/203 (49%), Gaps = 7/203 (3%)
Query: 27 HLAMTYTGLCILLALGDDLSRINRTALIQGVKALQTDEGNFSATLSGCESDMRFVYCAAC 86
HL T + + IL L D ++ I+ +++ VK LQ ++G+F+ + G E D RF +CA
Sbjct: 94 HLLYTLSAVQIL-TLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWG-EIDTRFSFCAVA 151
Query: 87 ISYILNDWSGFDIEKATDYVIKSIGYDYGIAQCPELESHGGXXXXXXXXXXXXDQLDKLS 146
+L ++EKA ++V+ + +D G P ESH G QL +++
Sbjct: 152 TLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVN 211
Query: 147 EAQIDGLKRWLVYRQID--GFQGRPNKPVDTCYSFWVGASLKILNALQLTNYGSNRRYVY 204
D L WL RQ+ G GRP K D CYS+WV ASLKI+ L + R ++
Sbjct: 212 S---DLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFIL 268
Query: 205 ETQDMVVGGFSKWPDTCTDPMHT 227
QD GGF+ P DP HT
Sbjct: 269 ACQDEETGGFADRPGDMVDPFHT 291
>U49245-1|AAA91473.1| 331|Homo sapiens geranylgeranyl transferase
type II beta-subunit protein.
Length = 331
Score = 114 bits (275), Expect = 3e-25
Identities = 69/203 (33%), Positives = 101/203 (49%), Gaps = 7/203 (3%)
Query: 27 HLAMTYTGLCILLALGDDLSRINRTALIQGVKALQTDEGNFSATLSGCESDMRFVYCAAC 86
HL T + + IL L D ++ I+ +++ VK LQ ++G+F+ + G E D RF +CA
Sbjct: 94 HLLYTLSAVQIL-TLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWG-EIDTRFSFCAVA 151
Query: 87 ISYILNDWSGFDIEKATDYVIKSIGYDYGIAQCPELESHGGXXXXXXXXXXXXDQLDKLS 146
+L ++EKA ++V+ + +D G P ESH G QL +++
Sbjct: 152 TFALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVN 211
Query: 147 EAQIDGLKRWLVYRQID--GFQGRPNKPVDTCYSFWVGASLKILNALQLTNYGSNRRYVY 204
D L WL RQ+ G GRP K D CYS+WV ASLKI+ L + R ++
Sbjct: 212 S---DLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFIL 268
Query: 205 ETQDMVVGGFSKWPDTCTDPMHT 227
QD GGF+ P DP HT
Sbjct: 269 ACQDEETGGFADRPGDMVDPFHT 291
>CR456941-1|CAG33222.1| 331|Homo sapiens RABGGTB protein.
Length = 331
Score = 114 bits (275), Expect = 3e-25
Identities = 69/203 (33%), Positives = 101/203 (49%), Gaps = 7/203 (3%)
Query: 27 HLAMTYTGLCILLALGDDLSRINRTALIQGVKALQTDEGNFSATLSGCESDMRFVYCAAC 86
HL T + + IL L D ++ I+ +++ VK LQ ++G+F+ + G E D RF +CA
Sbjct: 94 HLLYTLSAVQIL-TLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWG-EIDTRFSFCAVA 151
Query: 87 ISYILNDWSGFDIEKATDYVIKSIGYDYGIAQCPELESHGGXXXXXXXXXXXXDQLDKLS 146
+L ++EKA ++V+ + +D G P ESH G QL +++
Sbjct: 152 TLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVN 211
Query: 147 EAQIDGLKRWLVYRQID--GFQGRPNKPVDTCYSFWVGASLKILNALQLTNYGSNRRYVY 204
D L WL RQ+ G GRP K D CYS+WV ASLKI+ L + R ++
Sbjct: 212 S---DLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFIL 268
Query: 205 ETQDMVVGGFSKWPDTCTDPMHT 227
QD GGF+ P DP HT
Sbjct: 269 ACQDEETGGFADRPGDMVDPFHT 291
>BC020790-1|AAH20790.1| 331|Homo sapiens Rab
geranylgeranyltransferase, beta subunit protein.
Length = 331
Score = 114 bits (275), Expect = 3e-25
Identities = 69/203 (33%), Positives = 101/203 (49%), Gaps = 7/203 (3%)
Query: 27 HLAMTYTGLCILLALGDDLSRINRTALIQGVKALQTDEGNFSATLSGCESDMRFVYCAAC 86
HL T + + IL L D ++ I+ +++ VK LQ ++G+F+ + G E D RF +CA
Sbjct: 94 HLLYTLSAVQIL-TLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWG-EIDTRFSFCAVA 151
Query: 87 ISYILNDWSGFDIEKATDYVIKSIGYDYGIAQCPELESHGGXXXXXXXXXXXXDQLDKLS 146
+L ++EKA ++V+ + +D G P ESH G QL +++
Sbjct: 152 TLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVN 211
Query: 147 EAQIDGLKRWLVYRQID--GFQGRPNKPVDTCYSFWVGASLKILNALQLTNYGSNRRYVY 204
D L WL RQ+ G GRP K D CYS+WV ASLKI+ L + R ++
Sbjct: 212 S---DLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFIL 268
Query: 205 ETQDMVVGGFSKWPDTCTDPMHT 227
QD GGF+ P DP HT
Sbjct: 269 ACQDEETGGFADRPGDMVDPFHT 291
>AL357314-5|CAI22393.1| 331|Homo sapiens Rab
geranylgeranyltransferase, beta subunit protein.
Length = 331
Score = 114 bits (275), Expect = 3e-25
Identities = 69/203 (33%), Positives = 101/203 (49%), Gaps = 7/203 (3%)
Query: 27 HLAMTYTGLCILLALGDDLSRINRTALIQGVKALQTDEGNFSATLSGCESDMRFVYCAAC 86
HL T + + IL L D ++ I+ +++ VK LQ ++G+F+ + G E D RF +CA
Sbjct: 94 HLLYTLSAVQIL-TLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWG-EIDTRFSFCAVA 151
Query: 87 ISYILNDWSGFDIEKATDYVIKSIGYDYGIAQCPELESHGGXXXXXXXXXXXXDQLDKLS 146
+L ++EKA ++V+ + +D G P ESH G QL +++
Sbjct: 152 TLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVN 211
Query: 147 EAQIDGLKRWLVYRQID--GFQGRPNKPVDTCYSFWVGASLKILNALQLTNYGSNRRYVY 204
D L WL RQ+ G GRP K D CYS+WV ASLKI+ L + R ++
Sbjct: 212 S---DLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFIL 268
Query: 205 ETQDMVVGGFSKWPDTCTDPMHT 227
QD GGF+ P DP HT
Sbjct: 269 ACQDEETGGFADRPGDMVDPFHT 291
>Y08201-1|CAA69383.1| 331|Homo sapiens rab geranylgeranyl
transferase protein.
Length = 331
Score = 112 bits (270), Expect = 1e-24
Identities = 69/203 (33%), Positives = 100/203 (49%), Gaps = 7/203 (3%)
Query: 27 HLAMTYTGLCILLALGDDLSRINRTALIQGVKALQTDEGNFSATLSGCESDMRFVYCAAC 86
HL T + + IL L D ++ I+ +++ VK LQ ++G+F+ + G E D RF +CA
Sbjct: 94 HLLYTLSAVQIL-TLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWG-EIDTRFSFCAVA 151
Query: 87 ISYILNDWSGFDIEKATDYVIKSIGYDYGIAQCPELESHGGXXXXXXXXXXXXDQLDKLS 146
+L ++EKA ++V+ + D G P ESH G QL +++
Sbjct: 152 TLALLGKLDAINVEKAIEFVLSCMNSDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVT 211
Query: 147 EAQIDGLKRWLVYRQID--GFQGRPNKPVDTCYSFWVGASLKILNALQLTNYGSNRRYVY 204
D L WL RQ+ G GRP K D CYS+WV ASLKI+ L + R ++
Sbjct: 212 S---DLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFIL 268
Query: 205 ETQDMVVGGFSKWPDTCTDPMHT 227
QD GGF+ P DP HT
Sbjct: 269 ACQDEETGGFADRPGDMVDPFHT 291
>AB209023-1|BAD92260.1| 320|Homo sapiens Rab
geranylgeranyltransferase, beta subunit variant protein.
Length = 320
Score = 105 bits (252), Expect = 2e-22
Identities = 65/194 (33%), Positives = 97/194 (50%), Gaps = 7/194 (3%)
Query: 27 HLAMTYTGLCILLALGDDLSRINRTALIQGVKALQTDEGNFSATLSGCESDMRFVYCAAC 86
HL T + + IL L D ++ I+ +++ VK LQ ++G+F+ + G E D RF +CA
Sbjct: 94 HLLYTLSAVQIL-TLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWG-EIDTRFSFCAVA 151
Query: 87 ISYILNDWSGFDIEKATDYVIKSIGYDYGIAQCPELESHGGXXXXXXXXXXXXDQLDKLS 146
+L ++EKA ++V+ + +D G P ESH G QL +++
Sbjct: 152 TLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVN 211
Query: 147 EAQIDGLKRWLVYRQID--GFQGRPNKPVDTCYSFWVGASLKILNALQLTNYGSNRRYVY 204
D L WL RQ+ G GRP K D CYS+WV ASLKI+ L + R ++
Sbjct: 212 S---DLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFIL 268
Query: 205 ETQDMVVGGFSKWP 218
QD GGF+ P
Sbjct: 269 ACQDEETGGFADRP 282
>L10414-1|AAA86286.1| 387|Homo sapiens farnesyl-protein transferase
beta-subunit protein.
Length = 387
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/168 (31%), Positives = 84/168 (50%), Gaps = 9/168 (5%)
Query: 27 HLAMTYTGLCILLALGDDLSR--INRTALIQGVKALQTDEGNFSATLSGCESDMRFVYCA 84
HLA TY + L +G + + INR L+Q + +L+ +G+F + G E D+R YCA
Sbjct: 99 HLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGG-EVDVRSAYCA 157
Query: 85 ACISYILNDWSGFDIEKATDYVIKSIGYDYGIAQCPELESHGGXXXXXXXXXXXXDQLDK 144
A ++ + N + E +++ + ++ GI P +E+HGG L +
Sbjct: 158 ASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVI---LKR 214
Query: 145 LSEAQIDGLKRWLVYRQI---DGFQGRPNKPVDTCYSFWVGASLKILN 189
+ L +W+ RQ+ GFQGR NK VD CYSFW L +L+
Sbjct: 215 ERSLNLKSLLQWVTSRQMLFEGGFQGRCNKLVDGCYSFWQAGLLPLLH 262
>L00635-1|AAA35854.1| 437|Homo sapiens farnesyl-protein transferase
beta-subunit protein.
Length = 437
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/168 (31%), Positives = 84/168 (50%), Gaps = 9/168 (5%)
Query: 27 HLAMTYTGLCILLALGDDLSR--INRTALIQGVKALQTDEGNFSATLSGCESDMRFVYCA 84
HLA TY + L +G + + INR L+Q + +L+ +G+F + G E D+R YCA
Sbjct: 149 HLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGG-EVDVRSAYCA 207
Query: 85 ACISYILNDWSGFDIEKATDYVIKSIGYDYGIAQCPELESHGGXXXXXXXXXXXXDQLDK 144
A ++ + N + E +++ + ++ GI P +E+HGG L +
Sbjct: 208 ASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVI---LKR 264
Query: 145 LSEAQIDGLKRWLVYRQI---DGFQGRPNKPVDTCYSFWVGASLKILN 189
+ L +W+ RQ+ GFQGR NK VD CYSFW L +L+
Sbjct: 265 ERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLH 312
>BC020232-1|AAH20232.1| 437|Homo sapiens farnesyltransferase, CAAX
box, beta protein.
Length = 437
Score = 82.6 bits (195), Expect = 1e-15
Identities = 53/168 (31%), Positives = 84/168 (50%), Gaps = 9/168 (5%)
Query: 27 HLAMTYTGLCILLALGDDLSR--INRTALIQGVKALQTDEGNFSATLSGCESDMRFVYCA 84
HLA TY + L +G + + INR L+Q + +L+ +G+F + G E D+R YCA
Sbjct: 149 HLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGG-EVDVRSAYCA 207
Query: 85 ACISYILNDWSGFDIEKATDYVIKSIGYDYGIAQCPELESHGGXXXXXXXXXXXXDQLDK 144
A ++ + N + E +++ + ++ GI P +E+HGG L +
Sbjct: 208 ASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVI---LKR 264
Query: 145 LSEAQIDGLKRWLVYRQI---DGFQGRPNKPVDTCYSFWVGASLKILN 189
+ L +W+ RQ+ GFQGR NK VD CYSFW L +L+
Sbjct: 265 ERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLH 312
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.138 0.441
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 36,199,373
Number of Sequences: 224733
Number of extensions: 1217963
Number of successful extensions: 1596
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1562
Number of HSP's gapped (non-prelim): 16
length of query: 268
length of database: 73,234,838
effective HSP length: 89
effective length of query: 179
effective length of database: 53,233,601
effective search space: 9528814579
effective search space used: 9528814579
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 64 (29.9 bits)
- SilkBase 1999-2023 -