Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001493-TA|BGIBMGA001493-PA|IPR002035|von Willebrand
factor, type A, IPR013608|VWA N-terminal, IPR004010|Cache
(1174 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BX537437-1|CAD97679.1| 1137|Homo sapiens hypothetical protein pr... 178 1e-43
AF516695-1|AAN06672.1| 1120|Homo sapiens voltage-gated calcium c... 178 1e-43
BX537436-1|CAD97678.1| 974|Homo sapiens hypothetical protein pr... 177 1e-43
AF516696-1|AAN06673.1| 1091|Homo sapiens voltage-gated calcium c... 174 2e-42
AJ272268-1|CAB75962.1| 997|Homo sapiens calcium channel alpha2-... 167 2e-40
AJ272213-1|CAB75878.1| 519|Homo sapiens calcium channel alpha2-... 167 2e-40
BC117470-1|AAI17471.1| 1091|Homo sapiens calcium channel, voltag... 145 7e-34
BC117468-1|AAI17469.1| 1091|Homo sapiens calcium channel, voltag... 145 7e-34
AF083854-1|AAF03259.1| 1110|Homo sapiens dihydropyridine recepto... 145 7e-34
M76559-1|AAA51903.1| 1091|Homo sapiens calcium channel alpha-2b ... 144 1e-33
AJ251368-1|CAB86193.1| 1150|Homo sapiens calcium channel, alpha ... 139 6e-32
AJ251367-1|CAB86192.1| 1143|Homo sapiens calcium channel, alpha ... 139 6e-32
AF042792-1|AAB96913.1| 1145|Homo sapiens alpha 2 delta calcium c... 139 6e-32
AF040709-1|AAC70914.1| 1145|Homo sapiens putative tumor suppress... 139 6e-32
AB011130-1|BAA25484.1| 1145|Homo sapiens KIAA0558 protein protein. 139 6e-32
AF042793-1|AAB96914.1| 1076|Homo sapiens alpha 2 delta calcium c... 138 8e-32
AC008283-1|AAF19234.1| 170|Homo sapiens unknown protein. 92 9e-18
AC006145-1|AAD20938.1| 745|Homo sapiens WUGSC:H_DJ0560O14.1 pro... 54 4e-06
BX537603-1|CAD97793.1| 978|Homo sapiens hypothetical protein pr... 37 0.49
BC039301-1|AAH39301.1| 978|Homo sapiens CACHD1 protein protein. 37 0.49
AL590405-1|CAH70309.1| 1223|Homo sapiens cache domain containing... 37 0.49
AL355515-1|CAI22137.1| 1223|Homo sapiens cache domain containing... 37 0.49
AB046793-1|BAB13399.1| 1185|Homo sapiens KIAA1573 protein protein. 37 0.49
U43163-1|AAD05198.1| 930|Homo sapiens inter-alpha-trypsin inhib... 34 2.6
D38595-1|BAA07602.1| 930|Homo sapiens inter-alpha-trypsin inhib... 34 2.6
D38535-1|BAA07536.1| 930|Homo sapiens PK-120 precursor protein. 34 2.6
BC125064-1|AAI25065.1| 423|Homo sapiens ZNF253 protein protein. 34 2.6
BC125063-1|AAI25064.1| 499|Homo sapiens zinc finger protein 253... 34 2.6
BC065572-1|AAH65572.1| 423|Homo sapiens ZNF253 protein protein. 34 2.6
BC014148-1|AAH14148.2| 529|Homo sapiens ZNF253 protein protein. 34 2.6
AK074872-1|BAC11257.1| 402|Homo sapiens protein ( Homo sapiens ... 34 2.6
AB209388-1|BAD92625.1| 699|Homo sapiens inter-alpha (globulin) ... 34 2.6
>BX537437-1|CAD97679.1| 1137|Homo sapiens hypothetical protein
protein.
Length = 1137
Score = 178 bits (433), Expect = 1e-43
Identities = 119/394 (30%), Positives = 198/394 (50%), Gaps = 22/394 (5%)
Query: 126 NGTALVNKAADALEDLLTRRVKAAENIMRKAEELDKDETPPPDNYVFDHSVDLDKIKEKK 185
+G LV K ++ +E++L R+V+A +N++ AEE D + ++ VFD+ + I E+
Sbjct: 118 DGLELVRKFSEDMENMLRRKVEAVQNLVEAAEEADLNHEFN-ESLVFDYYNSV-LINER- 174
Query: 186 IPNQKGWFMPQNCTNLQKVPLNESNHFDG-KVSLQTSSVYVSLEVFECDPKVMKHIYWTE 244
++KG F+ L L + HF V+ SSV + V+ DP ++ +Y +E
Sbjct: 175 --DEKGNFVELGAEFL----LESNAHFSNLPVNTSISSVQLPTNVYNKDPDILNGVYMSE 228
Query: 245 GLLSTFKKNYAQDATTDFQYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVS 304
L + F +N+ +D T +QYF SA GF R YP W N +DCR R WY+
Sbjct: 229 ALNAVFVENFQRDPTLTWQYFGSATGFFRIYPGIKWTPDE----NGVITFDCRNRGWYIQ 284
Query: 305 AGGAPRDVLVLLDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCF 364
A +P+D+++L+D SGSM G IA+ VN++ +N+ V+ + CF
Sbjct: 285 AATSPKDIVILVDVSGSMKG-LRMTIAKHTITTILDTLGENDFVNIIAYNDYVHYIEPCF 343
Query: 365 NQKMVPANHVNSAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVL 424
+V A+ N + E VD AL+ A ++L KQ + C QAI+L
Sbjct: 344 KGILVQADRDNREHFKLLVEELMVKGVGVVDQALREAFQIL-KQFQEAKQGSLCNQAIML 402
Query: 425 LTDSMYDNYTDLVRHLD-PGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELIT 483
++D ++Y + + P +R+F + + D R+ +W++C GY+ ++ T
Sbjct: 403 ISDGAVEDYEPVFEKYNWPDCKVRVFTYLIGREVSFAD---RM-KWIACNNKGYYTQIST 458
Query: 484 HADVTEQVMSVLRVLVRPLVAQRDHRLRVFSDIY 517
AD E VM L VL RP+V DH + ++++ Y
Sbjct: 459 LADTQENVMEYLHVLSRPMVINHDHDI-IWTEAY 491
Score = 67.3 bits (157), Expect = 3e-10
Identities = 58/222 (26%), Positives = 99/222 (44%), Gaps = 22/222 (9%)
Query: 587 SVSVPVFDATTAEYPVNRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVVLHD 646
+V++PVF LLGV G D+ + L + P ++LG G L + G ++ H
Sbjct: 509 TVAMPVFSKKNETRSHGILLGVVGSDVALRELMKLAPRYKLGVHGYAFLNTNNGYILSHP 568
Query: 647 NLKPTF-DGDVL--RPGYRTVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNMTM 703
+L+P + +G L +P Y +VD ++E D + R +I++ETG ++M
Sbjct: 569 DLRPLYREGKKLKPKPNYNSVDLSEVE-----------WEDQAESLRTAMINRETGTLSM 617
Query: 704 YAKNIFEDGMRATLENRQYFWRRVLD-HYTVVVALPNPDAHWAGSESQFTMKLAEAALKS 762
K + G R YF+ + D +++ V L H G E L
Sbjct: 618 DVKVPMDKGKRVLFLTNDYFFTDISDTPFSLGVVLSR--GH--GEYILLGNTSVEEGLHD 673
Query: 763 LSRTDFAVQPDWLYC-RHVEP-HFDSREAE-VLHFIRRRSDE 801
L D A+ DW+YC ++P H + E ++ F+ R+ +
Sbjct: 674 LLHPDLALAGDWIYCITDIDPDHRKLSQLEAMIRFLARKDPD 715
>AF516695-1|AAN06672.1| 1120|Homo sapiens voltage-gated calcium
channel alpha(2)delta-4 subunit protein.
Length = 1120
Score = 178 bits (433), Expect = 1e-43
Identities = 119/394 (30%), Positives = 198/394 (50%), Gaps = 22/394 (5%)
Query: 126 NGTALVNKAADALEDLLTRRVKAAENIMRKAEELDKDETPPPDNYVFDHSVDLDKIKEKK 185
+G LV K ++ +E++L R+V+A +N++ AEE D + ++ VFD+ + I E+
Sbjct: 101 DGLELVRKFSEDMENMLRRKVEAVQNLVEAAEEADLNHEFN-ESLVFDYYNSV-LINER- 157
Query: 186 IPNQKGWFMPQNCTNLQKVPLNESNHFDG-KVSLQTSSVYVSLEVFECDPKVMKHIYWTE 244
++KG F+ L L + HF V+ SSV + V+ DP ++ +Y +E
Sbjct: 158 --DEKGNFVELGAEFL----LESNAHFSNLPVNTSISSVQLPTNVYNKDPDILNGVYMSE 211
Query: 245 GLLSTFKKNYAQDATTDFQYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVS 304
L + F +N+ +D T +QYF SA GF R YP W N +DCR R WY+
Sbjct: 212 ALNAVFVENFQRDPTLTWQYFGSATGFFRIYPGIKWTPDE----NGVITFDCRNRGWYIQ 267
Query: 305 AGGAPRDVLVLLDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCF 364
A +P+D+++L+D SGSM G IA+ VN++ +N+ V+ + CF
Sbjct: 268 AATSPKDIVILVDVSGSMKG-LRMTIAKHTITTILDTLGENDFVNIIAYNDYVHYIEPCF 326
Query: 365 NQKMVPANHVNSAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVL 424
+V A+ N + E VD AL+ A ++L KQ + C QAI+L
Sbjct: 327 KGILVQADRDNREHFKLLVEELMVKGVGVVDQALREAFQIL-KQFQEAKQGSLCNQAIML 385
Query: 425 LTDSMYDNYTDLVRHLD-PGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELIT 483
++D ++Y + + P +R+F + + D R+ +W++C GY+ ++ T
Sbjct: 386 ISDGAVEDYEPVFEKYNWPDCKVRVFTYLIGREVSFAD---RM-KWIACNNKGYYTQIST 441
Query: 484 HADVTEQVMSVLRVLVRPLVAQRDHRLRVFSDIY 517
AD E VM L VL RP+V DH + ++++ Y
Sbjct: 442 LADTQENVMEYLHVLSRPMVINHDHDI-IWTEAY 474
Score = 65.7 bits (153), Expect = 9e-10
Identities = 56/221 (25%), Positives = 96/221 (43%), Gaps = 20/221 (9%)
Query: 587 SVSVPVFDATTAEYPVNRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVVLHD 646
+V++PVF LLGV G D+ + L + P ++LG G L + G ++ H
Sbjct: 492 TVAMPVFSKKNETRSHGILLGVVGSDVALRELMKLAPRYKLGVHGYAFLNTNNGYILSHP 551
Query: 647 NLKPTF-DGDVL--RPGYRTVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNMTM 703
+L+P + +G L +P Y +VD ++E D + R +I++ETG ++M
Sbjct: 552 DLRPLYREGKKLKPKPNYNSVDLSEVE-----------WEDQAESLRTAMINRETGTLSM 600
Query: 704 YAKNIFEDGMRATLENRQYFWRRVLDHYTVVVALPNPDAHWAGSESQFTMKLAEAALKSL 763
K + G R YF+ + D +L + G E L L
Sbjct: 601 DVKVPMDKGKRVLFLTNDYFFTDISD---TPFSLGAVLSRGHGEYILLGNTSVEEGLHDL 657
Query: 764 SRTDFAVQPDWLYC-RHVEP-HFDSREAE-VLHFIRRRSDE 801
D A+ DW+YC ++P H + E ++ F+ R+ +
Sbjct: 658 LHPDLALAGDWIYCITDIDPDHRKLSQLEAMIRFLTRKDPD 698
>BX537436-1|CAD97678.1| 974|Homo sapiens hypothetical protein
protein.
Length = 974
Score = 177 bits (432), Expect = 1e-43
Identities = 119/394 (30%), Positives = 198/394 (50%), Gaps = 22/394 (5%)
Query: 126 NGTALVNKAADALEDLLTRRVKAAENIMRKAEELDKDETPPPDNYVFDHSVDLDKIKEKK 185
+G LV K ++ +E++L R+V+A +N++ AEE D + ++ VFD+ + I E+
Sbjct: 118 DGLELVRKFSEDMENMLRRKVEAVQNLVEAAEEADLNHEFN-ESLVFDYYNSV-LINER- 174
Query: 186 IPNQKGWFMPQNCTNLQKVPLNESNHFDG-KVSLQTSSVYVSLEVFECDPKVMKHIYWTE 244
++KG F+ L L + HF V+ SSV + V+ DP ++ +Y +E
Sbjct: 175 --DEKGNFVELGAEFL----LESNAHFSNLPVNTSISSVQLPTNVYNKDPDILNGVYMSE 228
Query: 245 GLLSTFKKNYAQDATTDFQYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVS 304
L + F +N+ +D T +QYF SA GF R YP W N +DCR R WY+
Sbjct: 229 ALNAVFVENFQRDPTLTWQYFGSATGFFRIYPGIKWTPDE----NGVITFDCRNRGWYIQ 284
Query: 305 AGGAPRDVLVLLDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCF 364
A +P+D+++L+D SGSM G IA+ VN++ +N+ V+ + CF
Sbjct: 285 AATSPKDIVILVDVSGSMKG-LRMTIAKHTITTILDTLGENDFVNIIAYNDYVHYIEPCF 343
Query: 365 NQKMVPANHVNSAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVL 424
+V A+ N + E VD AL+ A ++L KQ + C QAI+L
Sbjct: 344 KGILVQADRDNREHFKLLVEELMVNGVGVVDQALREAFQIL-KQFQEAKQGSLCNQAIML 402
Query: 425 LTDSMYDNYTDLVRHLD-PGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELIT 483
++D ++Y + + P +R+F + + D R+ +W++C GY+ ++ T
Sbjct: 403 ISDGAVEDYEPVFEKYNWPDCKVRVFTYLIGREVSFAD---RM-KWIACNNKGYYTQIST 458
Query: 484 HADVTEQVMSVLRVLVRPLVAQRDHRLRVFSDIY 517
AD E VM L VL RP+V DH + ++++ Y
Sbjct: 459 LADTQENVMEYLHVLSRPMVINHDHDI-IWTEAY 491
Score = 67.3 bits (157), Expect = 3e-10
Identities = 58/222 (26%), Positives = 99/222 (44%), Gaps = 22/222 (9%)
Query: 587 SVSVPVFDATTAEYPVNRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVVLHD 646
+V++PVF LLGV G D+ + L + P ++LG G L + G ++ H
Sbjct: 509 TVAMPVFSKKNETRSHGILLGVVGSDVALRELMKLAPRYKLGVHGYAFLNTNNGYILSHP 568
Query: 647 NLKPTF-DGDVL--RPGYRTVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNMTM 703
+L+P + +G L +P Y +VD ++E D + R +I++ETG ++M
Sbjct: 569 DLRPLYREGKKLKPKPNYNSVDLSEVE-----------WEDQAESLRTAMINRETGTLSM 617
Query: 704 YAKNIFEDGMRATLENRQYFWRRVLD-HYTVVVALPNPDAHWAGSESQFTMKLAEAALKS 762
K + G R YF+ + D +++ V L H G E L
Sbjct: 618 DVKVPMDKGKRVLFLTNDYFFTDISDTPFSLGVVLSR--GH--GEYILLGNTSVEEGLHD 673
Query: 763 LSRTDFAVQPDWLYC-RHVEP-HFDSREAE-VLHFIRRRSDE 801
L D A+ DW+YC ++P H + E ++ F+ R+ +
Sbjct: 674 LLHPDLALAGDWIYCITDIDPDHRKLSQLEAMIRFLTRKDPD 715
>AF516696-1|AAN06673.1| 1091|Homo sapiens voltage-gated calcium
channel alpha(2)delta-3 subunit protein.
Length = 1091
Score = 174 bits (423), Expect = 2e-42
Identities = 116/395 (29%), Positives = 193/395 (48%), Gaps = 24/395 (6%)
Query: 126 NGTALVNKAADALEDLLTRRVKAAENIMRKAEELD-KDETPPPDNYVFDHSVDLDKIKEK 184
+G LV K A +E++ ++ +A ++ AEE K E Y + ++V I E+
Sbjct: 83 DGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADLQYEYFNAV---LINER 139
Query: 185 KIPNQKGWFMPQNCTNLQKVPLNESNHFDG-KVSLQTSSVYVSLEVFECDPKVMKHIYWT 243
++ G F+ ++ L ++HF+ V++ S V V ++ DP ++ +YW+
Sbjct: 140 ---DKDGNFLELG----KEFILAPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWS 192
Query: 244 EGLLSTFKKNYAQDATTDFQYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYV 303
E L F N+ +D + +QYF SAKGF R YP W+ N +DCR R WY+
Sbjct: 193 ESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDE----NGVIAFDCRNRKWYI 248
Query: 304 SAGGAPRDVLVLLDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQC 363
A +P+DV++L+D SGSM G IA++ N++ +NE+++ + C
Sbjct: 249 QAATSPKDVVILVDVSGSMKG-LRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPC 307
Query: 364 FNQKMVPANHVNSAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIV 423
N +V A+ N E L + +D AL A +L + C QAI+
Sbjct: 308 LNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFN-HTGQGSICSQAIM 366
Query: 424 LLTDSMYDNY-TDLVRHLDPGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELI 482
L+TD D Y T ++ P +R+F + + D+ + W++CA G+F ++
Sbjct: 367 LITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLK----WMACANKGFFTQIS 422
Query: 483 THADVTEQVMSVLRVLVRPLVAQRDHRLRVFSDIY 517
T ADV E VM L VL RP V ++H + V+++ Y
Sbjct: 423 TLADVQENVMEYLHVLSRPKVIDQEHDV-VWTEAY 456
Score = 62.9 bits (146), Expect = 7e-09
Identities = 51/216 (23%), Positives = 92/216 (42%), Gaps = 19/216 (8%)
Query: 584 LEISVSVPVFDATTAEYPVNRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVV 643
L +V++PVF LLGV G D+P+ L +P ++LG G + + G ++
Sbjct: 475 LMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYIL 534
Query: 644 LHDNLKPTFDGDVLR--PGYRTVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNM 701
H L+ ++ R P Y +VD ++E D RN +++++TG
Sbjct: 535 THPELRLLYEEGKKRRKPNYSSVDLSEVE-----------WEDRDDVLRNAMVNRKTGKF 583
Query: 702 TMYAKNIFEDGMRATLENRQYFWRRVL-DHYTVVVALPNPDAHWAGSESQFTMKLAEAAL 760
+M K + G R + Y++ + +++ VAL + T+ E L
Sbjct: 584 SMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYF-FRGNVTI---EEGL 639
Query: 761 KSLSRTDFAVQPDWLYCRHVEPHFDSREAEVLHFIR 796
L D ++ +W YC + + H + R L I+
Sbjct: 640 HDLEHPDVSLADEWSYC-NTDLHPEHRHLSQLEAIK 674
>AJ272268-1|CAB75962.1| 997|Homo sapiens calcium channel
alpha2-delta3 subunit protein.
Length = 997
Score = 167 bits (407), Expect = 2e-40
Identities = 98/314 (31%), Positives = 157/314 (50%), Gaps = 13/314 (4%)
Query: 206 LNESNHFDG-KVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYAQDATTDFQY 264
L ++HF+ V++ S V V ++ DP ++ +YW+E L F N+ +D + +QY
Sbjct: 60 LAPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQY 119
Query: 265 FCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVLLDASGSMNG 324
F SAKGF R YP W+ N +DCR R WY+ A +P+DV++L+D SGSM G
Sbjct: 120 FGSAKGFFRQYPGIKWEPDE----NGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKG 175
Query: 325 SSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVNSAAMMEELR 384
IA++ N++ +NE+++ + C N +V A+ N E L
Sbjct: 176 -LRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLD 234
Query: 385 EYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNY-TDLVRHLDPG 443
+ +D AL A +L + C QAI+L+TD D Y T ++ P
Sbjct: 235 KLFAKGIGMLDIALNEAFNILSDFN-HTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPD 293
Query: 444 NNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVLRVLVRPLV 503
+R+F + + D+ + W++CA G+F ++ T ADV E VM L VL RP V
Sbjct: 294 RKVRIFTYLIGREAAFADNLK----WMACANKGFFTQISTLADVQENVMEYLHVLSRPKV 349
Query: 504 AQRDHRLRVFSDIY 517
++H + V+++ Y
Sbjct: 350 IDQEHDV-VWTEAY 362
Score = 62.9 bits (146), Expect = 7e-09
Identities = 51/216 (23%), Positives = 92/216 (42%), Gaps = 19/216 (8%)
Query: 584 LEISVSVPVFDATTAEYPVNRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVV 643
L +V++PVF LLGV G D+P+ L +P ++LG G + + G ++
Sbjct: 381 LMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYIL 440
Query: 644 LHDNLKPTFDGDVLR--PGYRTVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNM 701
H L+ ++ R P Y +VD ++E D RN +++++TG
Sbjct: 441 THPELRLLYEEGKKRRKPNYSSVDLSEVE-----------WEDRDDVLRNAMVNRKTGKF 489
Query: 702 TMYAKNIFEDGMRATLENRQYFWRRVL-DHYTVVVALPNPDAHWAGSESQFTMKLAEAAL 760
+M K + G R + Y++ + +++ VAL + T+ E L
Sbjct: 490 SMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYF-FRGNVTI---EEGL 545
Query: 761 KSLSRTDFAVQPDWLYCRHVEPHFDSREAEVLHFIR 796
L D ++ +W YC + + H + R L I+
Sbjct: 546 HDLEHPDVSLADEWSYC-NTDLHPEHRHLSQLEAIK 580
>AJ272213-1|CAB75878.1| 519|Homo sapiens calcium channel
alpha2-delta3 subunit protein.
Length = 519
Score = 167 bits (407), Expect = 2e-40
Identities = 98/314 (31%), Positives = 157/314 (50%), Gaps = 13/314 (4%)
Query: 206 LNESNHFDG-KVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYAQDATTDFQY 264
L ++HF+ V++ S V V ++ DP ++ +YW+E L F N+ +D + +QY
Sbjct: 60 LAPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQY 119
Query: 265 FCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVLLDASGSMNG 324
F SAKGF R YP W+ N +DCR R WY+ A +P+DV++L+D SGSM G
Sbjct: 120 FGSAKGFFRQYPGIKWEPDE----NGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKG 175
Query: 325 SSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVNSAAMMEELR 384
IA++ N++ +NE+++ + C N +V A+ N E L
Sbjct: 176 -LRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLD 234
Query: 385 EYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNY-TDLVRHLDPG 443
+ +D AL A +L + C QAI+L+TD D Y T ++ P
Sbjct: 235 KLFAKGIGMLDIALNEAFNILSDFN-HTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPD 293
Query: 444 NNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVLRVLVRPLV 503
+R+F + + D+ + W++CA G+F ++ T ADV E VM L VL RP V
Sbjct: 294 RKVRIFTYLIGREAAFADNLK----WMACANKGFFTQISTLADVQENVMEYLHVLSRPKV 349
Query: 504 AQRDHRLRVFSDIY 517
++H + V+++ Y
Sbjct: 350 IDQEHDV-VWTEAY 362
Score = 53.2 bits (122), Expect = 5e-06
Identities = 36/141 (25%), Positives = 62/141 (43%), Gaps = 13/141 (9%)
Query: 584 LEISVSVPVFDATTAEYPVNRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVV 643
L +V++PVF LLGV G D+P+ L +P ++LG G + + G ++
Sbjct: 375 LMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYIL 434
Query: 644 LHDNLKPTFDGDVLR--PGYRTVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNM 701
H L+ ++ R P Y +VD ++E D RN +++++TG
Sbjct: 435 THPELRLLYEEGKKRRKPNYSSVDLSEVE-----------WEDRDDVLRNAMVNRKTGKF 483
Query: 702 TMYAKNIFEDGMRATLENRQY 722
+M K + G R R +
Sbjct: 484 SMEVKKTVDKGFRCGAFQRSW 504
>BC117470-1|AAI17471.1| 1091|Homo sapiens calcium channel,
voltage-dependent, alpha 2/delta subunit 1 protein.
Length = 1091
Score = 145 bits (352), Expect = 7e-34
Identities = 111/443 (25%), Positives = 200/443 (45%), Gaps = 31/443 (6%)
Query: 85 STKSIENWAQRLSE---VFFEIESKLVKREELLSAFSDAMMVA-RNGTALVNKAADALED 140
S +I++W ++ E + S + + ++ + D V N LV AA +E
Sbjct: 29 SAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEK 88
Query: 141 LLTRRVKAAENIMRKAEELD-----KDETPPPDNYVFDHSVDLDKIKEKKIPNQKGWFMP 195
LL+ R KA + +AE++ +++ + ++ DLD K P +
Sbjct: 89 LLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYNAKDDLDPEKNDSEPGSQ----- 143
Query: 196 QNCTNLQKVPLNESNHFDGKVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYA 255
++ V + ++N F ++S Q ++V++ +++E V+ + WT L FKKN
Sbjct: 144 ----RIKPVFIEDAN-FGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNRE 198
Query: 256 QDATTDFQYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVL 315
+D + +Q F SA G R+YPA+ W D + N D+YD R R WY+ +P+D+L+L
Sbjct: 199 EDPSLLWQVFGSATGLARYYPASPWVDNSRTP-NKIDLYDVRRRPWYIQGAASPKDMLIL 257
Query: 316 LDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVN 375
+D SGS++G + ++I VNV FN + CF Q +V AN N
Sbjct: 258 VDVSGSVSGLTLKLIRTSVSEMLETLSDDDF-VNVASFNSNAQD-VSCF-QHLVQANVRN 314
Query: 376 SAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNYTD 435
+ + + T T +A + L + R +C + I+L TD + +
Sbjct: 315 KKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSR---ANCNKIIMLFTDGGEERAQE 371
Query: 436 LVRHLDPGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVL 495
+ + +R+F F G + R +W++C GY+ E+ + + L
Sbjct: 372 IFNKYNKDKKVRVFTF----SVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYL 427
Query: 496 RVLVRPLVAQRDHRLRV-FSDIY 517
VL RP+V D +V ++++Y
Sbjct: 428 DVLGRPMVLAGDKAKQVQWTNVY 450
Score = 53.6 bits (123), Expect = 4e-06
Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 22/203 (10%)
Query: 578 EELNYRLEISVSVPVFDATTA-EYPVNR----LLGVAGVDIPIDHLKLILPYHQLGAGGS 632
+ L L I+ ++PVF+ T E N +LGV GVD+ ++ +K + P L G
Sbjct: 452 DALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGY 511
Query: 633 IILVDHRGNVVLHDNLKPTFDGDVLRPGYRTVDFLDLEQPAVSHLPRQYLPDWLKFR-RN 691
+D G V+LH NL+P + P T+DFLD E L + +K RN
Sbjct: 512 YFAIDPNGYVLLHPNLQPK-NPKSQEP--VTLDFLDAE-----------LENDIKVEIRN 557
Query: 692 LIIDKETGNMTMYAKNIFEDGMRATLENRQYFWRRVL-DHYTVVVALPNPDAHWAGSESQ 750
+ID E+G T +D NR Y W V Y++ + LP ++ ++ +
Sbjct: 558 KMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLE 617
Query: 751 FTMKLAEAALKSLSRTDFAVQPD 773
T+ A + K + ++PD
Sbjct: 618 ETITQARSK-KGKMKDSETLKPD 639
>BC117468-1|AAI17469.1| 1091|Homo sapiens calcium channel,
voltage-dependent, alpha 2/delta subunit 1 protein.
Length = 1091
Score = 145 bits (352), Expect = 7e-34
Identities = 111/443 (25%), Positives = 200/443 (45%), Gaps = 31/443 (6%)
Query: 85 STKSIENWAQRLSE---VFFEIESKLVKREELLSAFSDAMMVA-RNGTALVNKAADALED 140
S +I++W ++ E + S + + ++ + D V N LV AA +E
Sbjct: 29 SAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEK 88
Query: 141 LLTRRVKAAENIMRKAEELD-----KDETPPPDNYVFDHSVDLDKIKEKKIPNQKGWFMP 195
LL+ R KA + +AE++ +++ + ++ DLD K P +
Sbjct: 89 LLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYNAKDDLDPEKNDSEPGSQ----- 143
Query: 196 QNCTNLQKVPLNESNHFDGKVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYA 255
++ V + ++N F ++S Q ++V++ +++E V+ + WT L FKKN
Sbjct: 144 ----RIKPVFIEDAN-FGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNRE 198
Query: 256 QDATTDFQYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVL 315
+D + +Q F SA G R+YPA+ W D + N D+YD R R WY+ +P+D+L+L
Sbjct: 199 EDPSLLWQVFGSATGLARYYPASPWVDNSRTP-NKIDLYDVRRRPWYIQGAASPKDMLIL 257
Query: 316 LDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVN 375
+D SGS++G + ++I VNV FN + CF Q +V AN N
Sbjct: 258 VDVSGSVSGLTLKLIRTSVSEMLETLSDDDF-VNVASFNSNAQD-VSCF-QHLVQANVRN 314
Query: 376 SAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNYTD 435
+ + + T T +A + L + R +C + I+L TD + +
Sbjct: 315 KKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSR---ANCNKIIMLFTDGGEERAQE 371
Query: 436 LVRHLDPGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVL 495
+ + +R+F F G + R +W++C GY+ E+ + + L
Sbjct: 372 IFNKYNKDKKVRVFTF----SVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYL 427
Query: 496 RVLVRPLVAQRDHRLRV-FSDIY 517
VL RP+V D +V ++++Y
Sbjct: 428 DVLGRPMVLAGDKAKQVQWTNVY 450
Score = 53.6 bits (123), Expect = 4e-06
Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 22/203 (10%)
Query: 578 EELNYRLEISVSVPVFDATTA-EYPVNR----LLGVAGVDIPIDHLKLILPYHQLGAGGS 632
+ L L I+ ++PVF+ T E N +LGV GVD+ ++ +K + P L G
Sbjct: 452 DALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGY 511
Query: 633 IILVDHRGNVVLHDNLKPTFDGDVLRPGYRTVDFLDLEQPAVSHLPRQYLPDWLKFR-RN 691
+D G V+LH NL+P + P T+DFLD E L + +K RN
Sbjct: 512 YFAIDPNGYVLLHPNLQPK-NPKSQEP--VTLDFLDAE-----------LENDIKVEIRN 557
Query: 692 LIIDKETGNMTMYAKNIFEDGMRATLENRQYFWRRVL-DHYTVVVALPNPDAHWAGSESQ 750
+ID E+G T +D NR Y W V Y++ + LP ++ ++ +
Sbjct: 558 KMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLE 617
Query: 751 FTMKLAEAALKSLSRTDFAVQPD 773
T+ A + K + ++PD
Sbjct: 618 ETITQARSK-KGKMKDSETLKPD 639
>AF083854-1|AAF03259.1| 1110|Homo sapiens dihydropyridine receptor
alpha 2 subunit protein.
Length = 1110
Score = 145 bits (352), Expect = 7e-34
Identities = 111/443 (25%), Positives = 200/443 (45%), Gaps = 31/443 (6%)
Query: 85 STKSIENWAQRLSE---VFFEIESKLVKREELLSAFSDAMMVA-RNGTALVNKAADALED 140
S +I++W ++ E + S + + ++ + D V N LV AA +E
Sbjct: 29 SAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEK 88
Query: 141 LLTRRVKAAENIMRKAEELD-----KDETPPPDNYVFDHSVDLDKIKEKKIPNQKGWFMP 195
LL+ R KA + +AE++ +++ + ++ DLD K P +
Sbjct: 89 LLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYNAKDDLDPEKNDSEPGSQ----- 143
Query: 196 QNCTNLQKVPLNESNHFDGKVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYA 255
++ V + ++N F ++S Q ++V++ +++E V+ + WT L FKKN
Sbjct: 144 ----RIKPVFIEDAN-FGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNRE 198
Query: 256 QDATTDFQYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVL 315
+D + +Q F SA G R+YPA+ W D + N D+YD R R WY+ +P+D+L+L
Sbjct: 199 EDPSLLWQVFGSATGLARYYPASPWVDNSRTP-NKIDLYDVRRRPWYIQGAASPKDMLIL 257
Query: 316 LDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVN 375
+D SGS++G + ++I VNV FN + CF Q +V AN N
Sbjct: 258 VDVSGSVSGLTLKLIRTSVSEMLETLSDDDF-VNVASFNSNAQD-VSCF-QHLVQANVRN 314
Query: 376 SAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNYTD 435
+ + + T T +A + L + R +C + I+L TD + +
Sbjct: 315 KKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSR---ANCNKIIMLFTDGGEERAQE 371
Query: 436 LVRHLDPGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVL 495
+ + +R+F F G + R +W++C GY+ E+ + + L
Sbjct: 372 IFNKYNKDKKVRVFTF----SVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYL 427
Query: 496 RVLVRPLVAQRDHRLRV-FSDIY 517
VL RP+V D +V ++++Y
Sbjct: 428 DVLGRPMVLAGDKAKQVQWTNVY 450
Score = 51.6 bits (118), Expect = 2e-05
Identities = 54/208 (25%), Positives = 89/208 (42%), Gaps = 13/208 (6%)
Query: 578 EELNYRLEISVSVPVFDATTA-EYPVNR----LLGVAGVDIPIDHLKLILPYHQLGAGGS 632
+ L L I+ ++PVF+ T E N +LGV GVD+ ++ +K + P L G
Sbjct: 452 DALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGY 511
Query: 633 IILVDHRGNVVLHDNLKPTFDG-----DVLRPGYRTVDFLDLEQPAVSHLPRQYLPDWLK 687
+D G V+LH NL+P G LR + ++P L + +K
Sbjct: 512 YFAIDPNGYVLLHPNLQPKPIGVGIPTINLRKRRPNIQNPKSQEPVTLDFLDAELENDIK 571
Query: 688 FR-RNLIIDKETGNMTMYAKNIFEDGMRATLENRQYFWRRVL-DHYTVVVALPNPDAHWA 745
RN +ID E+G T +D NR Y W V Y++ + LP ++
Sbjct: 572 VEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYI 631
Query: 746 GSESQFTMKLAEAALKSLSRTDFAVQPD 773
++ + T+ A + K + ++PD
Sbjct: 632 KAKLEETITQARSK-KGKMKDSETLKPD 658
>M76559-1|AAA51903.1| 1091|Homo sapiens calcium channel alpha-2b
subunit protein.
Length = 1091
Score = 144 bits (350), Expect = 1e-33
Identities = 111/443 (25%), Positives = 201/443 (45%), Gaps = 31/443 (6%)
Query: 85 STKSIENWAQRLSE---VFFEIESKLVKREELLSAFSDAMMVA-RNGTALVNKAADALED 140
S +I++W ++ E + S + + ++ + D V N LV AA +E
Sbjct: 29 SAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEK 88
Query: 141 LLTRRVKAAENIMRKAEELD-----KDETPPPDNYVFDHSVDLDKIKEKKIPNQKGWFMP 195
LL+ R KA ++ +AE++ +++ + ++ DLD K P +
Sbjct: 89 LLSNRSKALVSLALEAEKVQAAHQWREDFASNEVVYYNAKDDLDPEKNDSEPGSQ----- 143
Query: 196 QNCTNLQKVPLNESNHFDGKVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYA 255
++ V + ++N F ++S Q ++V++ +++E V+ + WT L FKKN
Sbjct: 144 ----RIKPVFIEDAN-FGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNRE 198
Query: 256 QDATTDFQYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVL 315
+D + +Q F SA G R+YPA+ W D + N D+YD R R WY+ +P+D+L+L
Sbjct: 199 EDPSLLWQVFGSATGLARYYPASPWVDNSRTP-NKIDLYDVRRRPWYIQGAASPKDMLIL 257
Query: 316 LDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVN 375
+D SGS++G + ++I VNV FN + CF Q +V AN N
Sbjct: 258 VDVSGSVSGLTLKLIRTSVSEMLETLSDDDF-VNVASFNSNAQD-VSCF-QHLVQANVRN 314
Query: 376 SAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNYTD 435
+ + + T T +A + L + R +C + I+L TD + +
Sbjct: 315 KKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSR---ANCNKIIMLFTDGGEERAQE 371
Query: 436 LVRHLDPGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVL 495
+ + +R+F F G + R +W++C GY+ E+ + + L
Sbjct: 372 IFNKYNKDKKVRVFRF----SVGQHNYERGPIQWMACENKGYYYEIPSIGAIRINTQEYL 427
Query: 496 RVLVRPLVAQRDHRLRV-FSDIY 517
VL RP+V D +V ++++Y
Sbjct: 428 DVLGRPMVLAGDKAKQVQWTNVY 450
Score = 53.6 bits (123), Expect = 4e-06
Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 22/203 (10%)
Query: 578 EELNYRLEISVSVPVFDATTA-EYPVNR----LLGVAGVDIPIDHLKLILPYHQLGAGGS 632
+ L L I+ ++PVF+ T E N +LGV GVD+ ++ +K + P L G
Sbjct: 452 DALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGY 511
Query: 633 IILVDHRGNVVLHDNLKPTFDGDVLRPGYRTVDFLDLEQPAVSHLPRQYLPDWLKFR-RN 691
+D G V+LH NL+P + P T+DFLD E L + +K RN
Sbjct: 512 YFAIDPNGYVLLHPNLQPK-NPKSQEP--VTLDFLDAE-----------LENDIKVEIRN 557
Query: 692 LIIDKETGNMTMYAKNIFEDGMRATLENRQYFWRRVL-DHYTVVVALPNPDAHWAGSESQ 750
+ID E+G T +D NR Y W V Y++ + LP ++ ++ +
Sbjct: 558 KMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLE 617
Query: 751 FTMKLAEAALKSLSRTDFAVQPD 773
T+ A + K + ++PD
Sbjct: 618 ETITQARSK-KGKMKDSETLKPD 639
>AJ251368-1|CAB86193.1| 1150|Homo sapiens calcium channel, alpha
2/delta subunit 2 protein.
Length = 1150
Score = 139 bits (336), Expect = 6e-32
Identities = 107/437 (24%), Positives = 198/437 (45%), Gaps = 23/437 (5%)
Query: 88 SIENWAQRLSEVFFEIESKLVKREELLSAFSD---AMMVARNGTA-LVNKAADALEDLLT 143
++++WA+RL + + ++L + D V N LV K A +E LL
Sbjct: 69 TMQHWARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLD 128
Query: 144 RRVKAAENIMRKAEELDKDETPPPDNYVFDHSVDLDKIKEKKIPNQKGWFMPQNC-TNLQ 202
R+V+A + + AE K DN + V D + ++ + + + + +
Sbjct: 129 RKVQALKRLADAAENFQKAHRWQ-DNIKEEDIVYYDAKADAELDDPESEDVERGSKASTL 187
Query: 203 KVPLNESNHFDGKVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYAQDATTDF 262
++ E +F KV+ ++V + ++++ ++ + WTE L + F +N QD T +
Sbjct: 188 RLDFIEDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLW 247
Query: 263 QYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVLLDASGSM 322
Q F SA G R+YPA W ++ D+YD R R WY+ +P+D+++++D SGS+
Sbjct: 248 QVFGSATGVTRYYPATPWRAPKKI-----DLYDVRRRPWYIQGASSPKDMVIIVDVSGSV 302
Query: 323 NGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVNSAAMMEE 382
+G + +++ + VNV FNEK + CF +V AN N E
Sbjct: 303 SGLTLKLM-KTSVCEMLDTLSDDDYVNVASFNEKAQP-VSCFTH-LVQANVRNKKVFKEA 359
Query: 383 LREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNYTDLVRHLD- 441
++ T +YA L+ + R +C + I++ TD D D+ +
Sbjct: 360 VQGMVAKGTTGYKAGFEYAFDQLQNSNITR---ANCNKMIMMFTDGGEDRVQDVFEKYNW 416
Query: 442 PGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVLRVLVRP 501
P +R+F F G + +W++CA GY+ E+ + + L VL RP
Sbjct: 417 PNRTVRVFTF----SVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRP 472
Query: 502 LV-AQRDHRLRVFSDIY 517
+V A ++ + ++++Y
Sbjct: 473 MVLAGKEAKQVQWTNVY 489
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Query: 570 EYGQYYEGEELNYRLEISVSVPVFDATT---AEYPVNRLLGVAGVDIPIDHLKLILPYHQ 626
++ YE + L L ++ ++PVF+ T E +LGV G+D+ ++ +K + P +
Sbjct: 484 QWTNVYE-DALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYT 542
Query: 627 LGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYRTVDFLDLE 670
LGA G + +D G V+LH NLKP + P T+DFLD E
Sbjct: 543 LGANGYVFAIDLNGYVLLHPNLKPQ-TTNFREP--VTLDFLDAE 583
>AJ251367-1|CAB86192.1| 1143|Homo sapiens calcium channel, alpha
2/delta subunit 2 protein.
Length = 1143
Score = 139 bits (336), Expect = 6e-32
Identities = 107/437 (24%), Positives = 198/437 (45%), Gaps = 23/437 (5%)
Query: 88 SIENWAQRLSEVFFEIESKLVKREELLSAFSD---AMMVARNGTA-LVNKAADALEDLLT 143
++++WA+RL + + ++L + D V N LV K A +E LL
Sbjct: 69 TMQHWARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLD 128
Query: 144 RRVKAAENIMRKAEELDKDETPPPDNYVFDHSVDLDKIKEKKIPNQKGWFMPQNC-TNLQ 202
R+V+A + + AE K DN + V D + ++ + + + + +
Sbjct: 129 RKVQALKRLADAAENFQKAHRWQ-DNIKEEDIVYYDAKADAELDDPESEDVERGSKASTL 187
Query: 203 KVPLNESNHFDGKVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYAQDATTDF 262
++ E +F KV+ ++V + ++++ ++ + WTE L + F +N QD T +
Sbjct: 188 RLDFIEDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLW 247
Query: 263 QYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVLLDASGSM 322
Q F SA G R+YPA W ++ D+YD R R WY+ +P+D+++++D SGS+
Sbjct: 248 QVFGSATGVTRYYPATPWRAPKKI-----DLYDVRRRPWYIQGASSPKDMVIIVDVSGSV 302
Query: 323 NGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVNSAAMMEE 382
+G + +++ + VNV FNEK + CF +V AN N E
Sbjct: 303 SGLTLKLM-KTSVCEMLDTLSDDDYVNVASFNEKAQP-VSCFTH-LVQANVRNKKVFKEA 359
Query: 383 LREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNYTDLVRHLD- 441
++ T +YA L+ + R +C + I++ TD D D+ +
Sbjct: 360 VQGMVAKGTTGYKAGFEYAFDQLQNSNITR---ANCNKMIMMFTDGGEDRVQDVFEKYNW 416
Query: 442 PGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVLRVLVRP 501
P +R+F F G + +W++CA GY+ E+ + + L VL RP
Sbjct: 417 PNRTVRVFTF----SVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRP 472
Query: 502 LV-AQRDHRLRVFSDIY 517
+V A ++ + ++++Y
Sbjct: 473 MVLAGKEAKQVQWTNVY 489
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Query: 570 EYGQYYEGEELNYRLEISVSVPVFDATT---AEYPVNRLLGVAGVDIPIDHLKLILPYHQ 626
++ YE + L L ++ ++PVF+ T E +LGV G+D+ ++ +K + P +
Sbjct: 484 QWTNVYE-DALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYT 542
Query: 627 LGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYRTVDFLDLE 670
LGA G + +D G V+LH NLKP + P T+DFLD E
Sbjct: 543 LGANGYVFAIDLNGYVLLHPNLKPQ-TTNFREP--VTLDFLDAE 583
>AF042792-1|AAB96913.1| 1145|Homo sapiens alpha 2 delta calcium
channel subunit isoform I protein.
Length = 1145
Score = 139 bits (336), Expect = 6e-32
Identities = 107/437 (24%), Positives = 198/437 (45%), Gaps = 23/437 (5%)
Query: 88 SIENWAQRLSEVFFEIESKLVKREELLSAFSD---AMMVARNGTA-LVNKAADALEDLLT 143
++++WA+RL + + ++L + D V N LV K A +E LL
Sbjct: 69 TMQHWARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLD 128
Query: 144 RRVKAAENIMRKAEELDKDETPPPDNYVFDHSVDLDKIKEKKIPNQKGWFMPQNC-TNLQ 202
R+V+A + + AE K DN + V D + ++ + + + + +
Sbjct: 129 RKVQALKRLADAAENFQKAHRWQ-DNIKEEDIVYYDAKADAELDDPESEDVERGSKASTL 187
Query: 203 KVPLNESNHFDGKVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYAQDATTDF 262
++ E +F KV+ ++V + ++++ ++ + WTE L + F +N QD T +
Sbjct: 188 RLDFIEDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLW 247
Query: 263 QYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVLLDASGSM 322
Q F SA G R+YPA W ++ D+YD R R WY+ +P+D+++++D SGS+
Sbjct: 248 QVFGSATGVTRYYPATPWRAPKKI-----DLYDVRRRPWYIQGASSPKDMVIIVDVSGSV 302
Query: 323 NGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVNSAAMMEE 382
+G + +++ + VNV FNEK + CF +V AN N E
Sbjct: 303 SGLTLKLM-KTSVCEMLDTLSDDDYVNVASFNEKAQP-VSCFTH-LVQANVRNKKVFKEA 359
Query: 383 LREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNYTDLVRHLD- 441
++ T +YA L+ + R +C + I++ TD D D+ +
Sbjct: 360 VQGMVAKGTTGYKAGFEYAFDQLQNSNITR---ANCNKMIMMFTDGGEDRVQDVFEKYNW 416
Query: 442 PGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVLRVLVRP 501
P +R+F F G + +W++CA GY+ E+ + + L VL RP
Sbjct: 417 PNRTVRVFTF----SVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRP 472
Query: 502 LV-AQRDHRLRVFSDIY 517
+V A ++ + ++++Y
Sbjct: 473 MVLAGKEAKQVQWTNVY 489
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Query: 570 EYGQYYEGEELNYRLEISVSVPVFDATT---AEYPVNRLLGVAGVDIPIDHLKLILPYHQ 626
++ YE + L L ++ ++PVF+ T E +LGV G+D+ ++ +K + P +
Sbjct: 484 QWTNVYE-DALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYT 542
Query: 627 LGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYRTVDFLDLE 670
LGA G + +D G V+LH NLKP + P T+DFLD E
Sbjct: 543 LGANGYVFAIDLNGYVLLHPNLKPQ-TTNFREP--VTLDFLDAE 583
>AF040709-1|AAC70914.1| 1145|Homo sapiens putative tumor suppressor
gene 26 protein alpha 2 delta calcium channel subunit
protein.
Length = 1145
Score = 139 bits (336), Expect = 6e-32
Identities = 107/437 (24%), Positives = 198/437 (45%), Gaps = 23/437 (5%)
Query: 88 SIENWAQRLSEVFFEIESKLVKREELLSAFSD---AMMVARNGTA-LVNKAADALEDLLT 143
++++WA+RL + + ++L + D V N LV K A +E LL
Sbjct: 69 TMQHWARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLD 128
Query: 144 RRVKAAENIMRKAEELDKDETPPPDNYVFDHSVDLDKIKEKKIPNQKGWFMPQNC-TNLQ 202
R+V+A + + AE K DN + V D + ++ + + + + +
Sbjct: 129 RKVQALKRLADAAENFQKAHRWQ-DNIKEEDIVYYDAKADAELDDPESEDVERGSKASTL 187
Query: 203 KVPLNESNHFDGKVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYAQDATTDF 262
++ E +F KV+ ++V + ++++ ++ + WTE L + F +N QD T +
Sbjct: 188 RLDFIEDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLW 247
Query: 263 QYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVLLDASGSM 322
Q F SA G R+YPA W ++ D+YD R R WY+ +P+D+++++D SGS+
Sbjct: 248 QVFGSATGVTRYYPATPWRAPKKI-----DLYDVRRRPWYIQGASSPKDMVIIVDVSGSV 302
Query: 323 NGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVNSAAMMEE 382
+G + +++ + VNV FNEK + CF +V AN N E
Sbjct: 303 SGLTLKLM-KTSVCEMLDTLSDDDYVNVASFNEKAQP-VSCFTH-LVQANVRNKKVFKEA 359
Query: 383 LREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNYTDLVRHLD- 441
++ T +YA L+ + R +C + I++ TD D D+ +
Sbjct: 360 VQGMVAKGTTGYKAGFEYAFDQLQNSNITR---ANCNKMIMMFTDGGEDRVQDVFEKYNW 416
Query: 442 PGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVLRVLVRP 501
P +R+F F G + +W++CA GY+ E+ + + L VL RP
Sbjct: 417 PNRTVRVFTF----SVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRP 472
Query: 502 LV-AQRDHRLRVFSDIY 517
+V A ++ + ++++Y
Sbjct: 473 MVLAGKEAKQVQWTNVY 489
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Query: 570 EYGQYYEGEELNYRLEISVSVPVFDATT---AEYPVNRLLGVAGVDIPIDHLKLILPYHQ 626
++ YE + L L ++ ++PVF+ T E +LGV G+D+ ++ +K + P +
Sbjct: 484 QWTNVYE-DALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYT 542
Query: 627 LGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYRTVDFLDLE 670
LGA G + +D G V+LH NLKP + P T+DFLD E
Sbjct: 543 LGANGYVFAIDLNGYVLLHPNLKPQ-TTNFREP--VTLDFLDAE 583
>AB011130-1|BAA25484.1| 1145|Homo sapiens KIAA0558 protein protein.
Length = 1145
Score = 139 bits (336), Expect = 6e-32
Identities = 107/437 (24%), Positives = 198/437 (45%), Gaps = 23/437 (5%)
Query: 88 SIENWAQRLSEVFFEIESKLVKREELLSAFSD---AMMVARNGTA-LVNKAADALEDLLT 143
++++WA+RL + + ++L + D V N LV K A +E LL
Sbjct: 69 TMQHWARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLD 128
Query: 144 RRVKAAENIMRKAEELDKDETPPPDNYVFDHSVDLDKIKEKKIPNQKGWFMPQNC-TNLQ 202
R+V+A + + AE K DN + V D + ++ + + + + +
Sbjct: 129 RKVQALKRLADAAENFQKAHRWQ-DNIKEEDIVYYDAKADAELDDPESEDVERGSKASTL 187
Query: 203 KVPLNESNHFDGKVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYAQDATTDF 262
++ E +F KV+ ++V + ++++ ++ + WTE L + F +N QD T +
Sbjct: 188 RLDFIEDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLW 247
Query: 263 QYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVLLDASGSM 322
Q F SA G R+YPA W ++ D+YD R R WY+ +P+D+++++D SGS+
Sbjct: 248 QVFGSATGVTRYYPATPWRAPKKI-----DLYDVRRRPWYIQGASSPKDMVIIVDVSGSV 302
Query: 323 NGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVNSAAMMEE 382
+G + +++ + VNV FNEK + CF +V AN N E
Sbjct: 303 SGLTLKLM-KTSVCEMLDTLSDDDYVNVASFNEKAQP-VSCFTH-LVQANVRNKKVFKEA 359
Query: 383 LREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNYTDLVRHLD- 441
++ T +YA L+ + R +C + I++ TD D D+ +
Sbjct: 360 VQGMVAKGTTGYKAGFEYAFDQLQNSNITR---ANCNKMIMMFTDGGEDRVQDVFEKYNW 416
Query: 442 PGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVLRVLVRP 501
P +R+F F G + +W++CA GY+ E+ + + L VL RP
Sbjct: 417 PNRTVRVFTF----SVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRP 472
Query: 502 LV-AQRDHRLRVFSDIY 517
+V A ++ + ++++Y
Sbjct: 473 MVLAGKEAKQVQWTNVY 489
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Query: 570 EYGQYYEGEELNYRLEISVSVPVFDATT---AEYPVNRLLGVAGVDIPIDHLKLILPYHQ 626
++ YE + L L ++ ++PVF+ T E +LGV G+D+ ++ +K + P +
Sbjct: 484 QWTNVYE-DALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYT 542
Query: 627 LGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYRTVDFLDLE 670
LGA G + +D G V+LH NLKP + P T+DFLD E
Sbjct: 543 LGANGYVFAIDLNGYVLLHPNLKPQ-TTNFREP--VTLDFLDAE 583
>AF042793-1|AAB96914.1| 1076|Homo sapiens alpha 2 delta calcium
channel subunit isoform II protein.
Length = 1076
Score = 138 bits (335), Expect = 8e-32
Identities = 107/436 (24%), Positives = 197/436 (45%), Gaps = 23/436 (5%)
Query: 89 IENWAQRLSEVFFEIESKLVKREELLSAFSD---AMMVARNGTA-LVNKAADALEDLLTR 144
+++WA+RL + + ++L + D V N LV K A +E LL R
Sbjct: 1 MQHWARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDR 60
Query: 145 RVKAAENIMRKAEELDKDETPPPDNYVFDHSVDLDKIKEKKIPNQKGWFMPQNC-TNLQK 203
+V+A + + AE K DN + V D + ++ + + + + + +
Sbjct: 61 KVQALKRLADAAENFQKAHRWQ-DNIKEEDIVYYDAKADAELDDPESEDVERGSKASTLR 119
Query: 204 VPLNESNHFDGKVSLQTSSVYVSLEVFECDPKVMKHIYWTEGLLSTFKKNYAQDATTDFQ 263
+ E +F KV+ ++V + ++++ ++ + WTE L + F +N QD T +Q
Sbjct: 120 LDFIEDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQ 179
Query: 264 YFCSAKGFLRHYPAALWDDMHQLKLNTDDVYDCRLRSWYVSAGGAPRDVLVLLDASGSMN 323
F SA G R+YPA W ++ D+YD R R WY+ +P+D+++++D SGS++
Sbjct: 180 VFGSATGVTRYYPATPWRAPKKI-----DLYDVRRRPWYIQGASSPKDMVIIVDVSGSVS 234
Query: 324 GSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKMVPANHVNSAAMMEEL 383
G + +++ + VNV FNEK + CF +V AN N E +
Sbjct: 235 GLTLKLM-KTSVCEMLDTLSDDDYVNVASFNEKAQP-VSCFTH-LVQANVRNKKVFKEAV 291
Query: 384 REYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTDSMYDNYTDLVRHLD-P 442
+ T +YA L+ + R +C + I++ TD D D+ + P
Sbjct: 292 QGMVAKGTTGYKAGFEYAFDQLQNSNITR---ANCNKMIMMFTDGGEDRVQDVFEKYNWP 348
Query: 443 GNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDGYFAELITHADVTEQVMSVLRVLVRPL 502
+R+F F G + +W++CA GY+ E+ + + L VL RP+
Sbjct: 349 NRTVRVFTF----SVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPM 404
Query: 503 V-AQRDHRLRVFSDIY 517
V A ++ + ++++Y
Sbjct: 405 VLAGKEAKQVQWTNVY 420
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Query: 570 EYGQYYEGEELNYRLEISVSVPVFDATT---AEYPVNRLLGVAGVDIPIDHLKLILPYHQ 626
++ YE + L L ++ ++PVF+ T E +LGV G+D+ ++ +K + P +
Sbjct: 415 QWTNVYE-DALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYT 473
Query: 627 LGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYRTVDFLDLE 670
LGA G + +D G V+LH NLKP + P T+DFLD E
Sbjct: 474 LGANGYVFAIDLNGYVLLHPNLKPQ-TTNFREP--VTLDFLDAE 514
>AC008283-1|AAF19234.1| 170|Homo sapiens unknown protein.
Length = 170
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/170 (31%), Positives = 81/170 (47%), Gaps = 4/170 (2%)
Query: 236 VMKHIYWTEGLLSTFKKNYAQDATTDFQYFCSAKGFLRHYPAALWDDMHQLKLNTDDVYD 295
V+ + WT L FKKN +D + +Q F SA G R+YPA+ W D + N D+YD
Sbjct: 3 VLNELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTP-NKIDLYD 61
Query: 296 CRLRSWYVSAGGAPRDVLVLLDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNE 355
R R WY+ +P+D+L+L+D SGS++G + ++I VNV FN
Sbjct: 62 VRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDF-VNVASFNS 120
Query: 356 KVNSLIQCFNQKMVPANHVNSAAMMEELREYTKVNETKVDYALKYAIKLL 405
+ CF Q +V AN N + + + T T +A + L
Sbjct: 121 NAQD-VSCF-QHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQL 168
>AC006145-1|AAD20938.1| 745|Homo sapiens WUGSC:H_DJ0560O14.1
protein.
Length = 745
Score = 53.6 bits (123), Expect = 4e-06
Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 22/203 (10%)
Query: 578 EELNYRLEISVSVPVFDATTA-EYPVNR----LLGVAGVDIPIDHLKLILPYHQLGAGGS 632
+ L L I+ ++PVF+ T E N +LGV GVD+ ++ +K + P L G
Sbjct: 106 DALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGY 165
Query: 633 IILVDHRGNVVLHDNLKPTFDGDVLRPGYRTVDFLDLEQPAVSHLPRQYLPDWLKFR-RN 691
+D G V+LH NL+P + P T+DFLD E L + +K RN
Sbjct: 166 YFAIDPNGYVLLHPNLQPK-NPKSQEP--VTLDFLDAE-----------LENDIKVEIRN 211
Query: 692 LIIDKETGNMTMYAKNIFEDGMRATLENRQYFWRRVL-DHYTVVVALPNPDAHWAGSESQ 750
+ID E+G T +D NR Y W V Y++ + LP ++ ++ +
Sbjct: 212 KMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLE 271
Query: 751 FTMKLAEAALKSLSRTDFAVQPD 773
T+ A + K + ++PD
Sbjct: 272 ETITQARSK-KGKMKDSETLKPD 293
Score = 40.7 bits (91), Expect = 0.030
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 417 SCQQAIVLLTDSMYDNYTDLVRHLDPGNNIRLFVFWLHDRYGLRDDTRRLAEWLSCARDG 476
+C + I+L TD + ++ + +R+F F + G + R +W++C G
Sbjct: 7 NCNKIIMLFTDGGEERAQEIFNKYNKDKKVRVFTFSV----GQHNYDRGPIQWMACENKG 62
Query: 477 YFAELITHADVTEQVMSVLRVLVRPLVAQRDHRLRV-FSDIY 517
Y+ E+ + + L VL RP+V D +V ++++Y
Sbjct: 63 YYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVY 104
>BX537603-1|CAD97793.1| 978|Homo sapiens hypothetical protein
protein.
Length = 978
Score = 36.7 bits (81), Expect = 0.49
Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 6/127 (4%)
Query: 603 NRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYR 662
N LLG+ GVD+ + ++ + Y+Q L+D +G ++H +L + + P
Sbjct: 181 NLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPY--LLSEPPLH 238
Query: 663 TVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNMTMYAKNIFEDGMRATLENRQY 722
T D + E L RQ + L +I +++ + + E G A N Y
Sbjct: 239 T-DIIHYENIPKFELVRQNILS-LPLGSQIIAVPVNSSLSWHINKLRETGKEA--YNVSY 294
Query: 723 FWRRVLD 729
W+ V D
Sbjct: 295 AWKMVQD 301
>BC039301-1|AAH39301.1| 978|Homo sapiens CACHD1 protein protein.
Length = 978
Score = 36.7 bits (81), Expect = 0.49
Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 6/127 (4%)
Query: 603 NRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYR 662
N LLG+ GVD+ + ++ + Y+Q L+D +G ++H +L + + P
Sbjct: 181 NLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPY--LLSEPPLH 238
Query: 663 TVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNMTMYAKNIFEDGMRATLENRQY 722
T D + E L RQ + L +I +++ + + E G A N Y
Sbjct: 239 T-DIIHYENIPKFELVRQNILS-LPLGSQIIAVPVNSSLSWHINKLRETGKEA--YNVSY 294
Query: 723 FWRRVLD 729
W+ V D
Sbjct: 295 AWKMVQD 301
>AL590405-1|CAH70309.1| 1223|Homo sapiens cache domain containing 1
protein.
Length = 1223
Score = 36.7 bits (81), Expect = 0.49
Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 6/127 (4%)
Query: 603 NRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYR 662
N LLG+ GVD+ + ++ + Y+Q L+D +G ++H +L + + P
Sbjct: 426 NLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPY--LLSEPPLH 483
Query: 663 TVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNMTMYAKNIFEDGMRATLENRQY 722
T D + E L RQ + L +I +++ + + E G A N Y
Sbjct: 484 T-DIIHYENIPKFELVRQNILS-LPLGSQIIAVPVNSSLSWHINKLRETGKEA--YNVSY 539
Query: 723 FWRRVLD 729
W+ V D
Sbjct: 540 AWKMVQD 546
>AL355515-1|CAI22137.1| 1223|Homo sapiens cache domain containing 1
protein.
Length = 1223
Score = 36.7 bits (81), Expect = 0.49
Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 6/127 (4%)
Query: 603 NRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYR 662
N LLG+ GVD+ + ++ + Y+Q L+D +G ++H +L + + P
Sbjct: 426 NLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPY--LLSEPPLH 483
Query: 663 TVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNMTMYAKNIFEDGMRATLENRQY 722
T D + E L RQ + L +I +++ + + E G A N Y
Sbjct: 484 T-DIIHYENIPKFELVRQNILS-LPLGSQIIAVPVNSSLSWHINKLRETGKEA--YNVSY 539
Query: 723 FWRRVLD 729
W+ V D
Sbjct: 540 AWKMVQD 546
>AB046793-1|BAB13399.1| 1185|Homo sapiens KIAA1573 protein protein.
Length = 1185
Score = 36.7 bits (81), Expect = 0.49
Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 6/127 (4%)
Query: 603 NRLLGVAGVDIPIDHLKLILPYHQLGAGGSIILVDHRGNVVLHDNLKPTFDGDVLRPGYR 662
N LLG+ GVD+ + ++ + Y+Q L+D +G ++H +L + + P
Sbjct: 388 NLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPY--LLSEPPLH 445
Query: 663 TVDFLDLEQPAVSHLPRQYLPDWLKFRRNLIIDKETGNMTMYAKNIFEDGMRATLENRQY 722
T D + E L RQ + L +I +++ + + E G A N Y
Sbjct: 446 T-DIIHYENIPKFELVRQNILS-LPLGSQIIAVPVNSSLSWHINKLRETGKEA--YNVSY 501
Query: 723 FWRRVLD 729
W+ V D
Sbjct: 502 AWKMVQD 508
>U43163-1|AAD05198.1| 930|Homo sapiens inter-alpha-trypsin
inhibitor family heavy chain-related protein protein.
Length = 930
Score = 34.3 bits (75), Expect = 2.6
Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 309 PRDVLVLLDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKM 368
P++V+ ++D SGSM+G Q E Q N++ F+ + + +
Sbjct: 272 PKNVVFVIDKSGSMSGRKIQQ-TREALIKILDDLSPRDQFNLIVFSTEATQ----WRPSL 326
Query: 369 VPANHVNSAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTD 427
VPA+ N + T ++ A+ A++LL P+ I+LLTD
Sbjct: 327 VPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTD 385
>D38595-1|BAA07602.1| 930|Homo sapiens inter-alpha-trypsin
inhibitor family heavy chain-related protein (IHRP)
protein.
Length = 930
Score = 34.3 bits (75), Expect = 2.6
Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 309 PRDVLVLLDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKM 368
P++V+ ++D SGSM+G Q E Q N++ F+ + + +
Sbjct: 272 PKNVVFVIDKSGSMSGRKIQQ-TREALIKILDDLSPRDQFNLIVFSTEATQ----WRPSL 326
Query: 369 VPANHVNSAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTD 427
VPA+ N + T ++ A+ A++LL P+ I+LLTD
Sbjct: 327 VPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTD 385
>D38535-1|BAA07536.1| 930|Homo sapiens PK-120 precursor protein.
Length = 930
Score = 34.3 bits (75), Expect = 2.6
Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 309 PRDVLVLLDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKM 368
P++V+ ++D SGSM+G Q E Q N++ F+ + + +
Sbjct: 272 PKNVVFVIDKSGSMSGRKIQQ-TREALIKILDDLSPRDQFNLIVFSTEATQ----WRPSL 326
Query: 369 VPANHVNSAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTD 427
VPA+ N + T ++ A+ A++LL P+ I+LLTD
Sbjct: 327 VPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTD 385
>BC125064-1|AAI25065.1| 423|Homo sapiens ZNF253 protein protein.
Length = 423
Score = 34.3 bits (75), Expect = 2.6
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 822 EKTYQCDEGLMARLCKDAIATDKWAREHEHPHRARDCSTCELGSITTFFASENLTLGSNI 881
EK Y+C+E A + T K E P+R R+C TT F+ E + G
Sbjct: 261 EKPYKCEECGKAFHLSSHLTTHKILHTGEKPYRCRECGKA-FNHSTTLFSHEKIHTGEKP 319
Query: 882 YR 883
Y+
Sbjct: 320 YK 321
>BC125063-1|AAI25064.1| 499|Homo sapiens zinc finger protein 253
protein.
Length = 499
Score = 34.3 bits (75), Expect = 2.6
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 822 EKTYQCDEGLMARLCKDAIATDKWAREHEHPHRARDCSTCELGSITTFFASENLTLGSNI 881
EK Y+C+E A + T K E P+R R+C TT F+ E + G
Sbjct: 337 EKPYKCEECGKAFHLSSHLTTHKILHTGEKPYRCRECGKA-FNHSTTLFSHEKIHTGEKP 395
Query: 882 YR 883
Y+
Sbjct: 396 YK 397
>BC065572-1|AAH65572.1| 423|Homo sapiens ZNF253 protein protein.
Length = 423
Score = 34.3 bits (75), Expect = 2.6
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 822 EKTYQCDEGLMARLCKDAIATDKWAREHEHPHRARDCSTCELGSITTFFASENLTLGSNI 881
EK Y+C+E A + T K E P+R R+C TT F+ E + G
Sbjct: 261 EKPYKCEECGKAFHLSSHLTTHKILHTGEKPYRCRECGKA-FNHSTTLFSHEKIHTGEKP 319
Query: 882 YR 883
Y+
Sbjct: 320 YK 321
>BC014148-1|AAH14148.2| 529|Homo sapiens ZNF253 protein protein.
Length = 529
Score = 34.3 bits (75), Expect = 2.6
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 822 EKTYQCDEGLMARLCKDAIATDKWAREHEHPHRARDCSTCELGSITTFFASENLTLGSNI 881
EK Y+C+E A + T K E P+R R+C TT F+ E + G
Sbjct: 367 EKPYKCEECGKAFHLSSHLTTHKILHTGEKPYRCRECGKA-FNHSTTLFSHEKIHTGEKP 425
Query: 882 YR 883
Y+
Sbjct: 426 YK 427
>AK074872-1|BAC11257.1| 402|Homo sapiens protein ( Homo sapiens
cDNA FLJ90391 fis, clone NT2RP2005535, moderately
similar to ZINC FINGER PROTEIN 85. ).
Length = 402
Score = 34.3 bits (75), Expect = 2.6
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 822 EKTYQCDEGLMARLCKDAIATDKWAREHEHPHRARDCSTCELGSITTFFASENLTLGSNI 881
EK Y+C+E A + T K E P+R R+C TT F+ E + G
Sbjct: 240 EKPYKCEECGKAFHLSSHLTTHKILHTGEKPYRCRECGKA-FNHSTTLFSHEKIHTGEKP 298
Query: 882 YR 883
Y+
Sbjct: 299 YK 300
>AB209388-1|BAD92625.1| 699|Homo sapiens inter-alpha (globulin)
inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)
protein.
Length = 699
Score = 34.3 bits (75), Expect = 2.6
Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 309 PRDVLVLLDASGSMNGSSNQVIAEEFXXXXXXXXXXXXQVNVLYFNEKVNSLIQCFNQKM 368
P++V+ ++D SGSM+G Q E Q N++ F+ + + +
Sbjct: 257 PKNVVFVIDKSGSMSGRKIQQ-TREALIKILDDLSPRDQFNLIVFSTEATQ----WRPSL 311
Query: 369 VPANHVNSAAMMEELREYTKVNETKVDYALKYAIKLLRKQRLIRDRPKSCQQAIVLLTD 427
VPA+ N + T ++ A+ A++LL P+ I+LLTD
Sbjct: 312 VPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTD 370
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.135 0.409
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 159,399,524
Number of Sequences: 224733
Number of extensions: 6330682
Number of successful extensions: 13135
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 12993
Number of HSP's gapped (non-prelim): 81
length of query: 1174
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1076
effective length of database: 51,211,004
effective search space: 55103040304
effective search space used: 55103040304
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 71 (32.7 bits)
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