Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001473-TA|BGIBMGA001473-PA|IPR004841|Amino acid
permease-associated region
(767 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q25479 Cluster: Bumetanide-sensitive sodium-(potassium)... 417 e-115
UniRef50_Q16UI2 Cluster: Kidney-specific Na-K-Cl cotransport pro... 384 e-105
UniRef50_Q9VTW8 Cluster: CG4357-PA, isoform A; n=9; Coelomata|Re... 301 6e-80
UniRef50_Q9U6A3 Cluster: Na+/K+/2Cl-cotransporter; n=3; Heterotr... 272 2e-71
UniRef50_P55011 Cluster: Solute carrier family 12 member 2 (Bume... 248 6e-64
UniRef50_A7S4G9 Cluster: Predicted protein; n=2; Nematostella ve... 242 2e-62
UniRef50_Q91412 Cluster: Basolateral Na(+)-K(+)-Cl-cotransporter... 236 1e-60
UniRef50_A7RG55 Cluster: Predicted protein; n=1; Nematostella ve... 228 4e-58
UniRef50_P59158 Cluster: Solute carrier family 12 member 3; n=13... 228 4e-58
UniRef50_P55017 Cluster: Solute carrier family 12 member 3; n=45... 228 4e-58
UniRef50_Q1LX46 Cluster: Novel protein similar to vertebrate sol... 223 2e-56
UniRef50_UPI0000E46F80 Cluster: PREDICTED: similar to bumetanide... 222 2e-56
UniRef50_Q4SHN3 Cluster: Chromosome 5 SCAF14581, whole genome sh... 217 7e-55
UniRef50_Q8JHB5 Cluster: Renal Na-K-Cl cotransporter isoform AFn... 208 4e-52
UniRef50_UPI000155D209 Cluster: PREDICTED: similar to NaCl elect... 201 5e-50
UniRef50_P34261 Cluster: Uncharacterized amino-acid permease B03... 154 1e-35
UniRef50_Q8IUN5 Cluster: SLC12A1 protein; n=27; Euteleostomi|Rep... 153 2e-35
UniRef50_UPI000051AA81 Cluster: PREDICTED: similar to sodium chl... 130 2e-28
UniRef50_A0LPD8 Cluster: Amino acid permease-associated region; ... 128 7e-28
UniRef50_Q9C258 Cluster: Related to na+/k+/2cl-cotransporter; n=... 128 7e-28
UniRef50_A2FMM0 Cluster: Amino acid permease family protein; n=2... 116 2e-24
UniRef50_Q5B4Q2 Cluster: Putative uncharacterized protein; n=1; ... 116 2e-24
UniRef50_UPI000023EFC2 Cluster: hypothetical protein FG05147.1; ... 116 3e-24
UniRef50_A0AV02 Cluster: Solute carrier family 12 member 8; n=25... 115 4e-24
UniRef50_Q8VI23-3 Cluster: Isoform 3 of Q8VI23 ; n=4; Eutheria|R... 114 1e-23
UniRef50_Q2S0B7 Cluster: Na-K-Cl cotransporter, putative; n=6; B... 113 2e-23
UniRef50_Q0UWR5 Cluster: Putative uncharacterized protein; n=1; ... 112 4e-23
UniRef50_O46100 Cluster: CG12773-PA; n=6; Endopterygota|Rep: CG1... 110 1e-22
UniRef50_A4QUB1 Cluster: Putative uncharacterized protein; n=1; ... 110 1e-22
UniRef50_UPI0000DB7B57 Cluster: PREDICTED: similar to CG12773-PA... 109 3e-22
UniRef50_A2QI38 Cluster: Complex: coimmunoprecipitation suggest ... 109 3e-22
UniRef50_Q4P5L1 Cluster: Putative uncharacterized protein; n=1; ... 107 1e-21
UniRef50_A7RQ45 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 107 1e-21
UniRef50_A2DXA4 Cluster: Amino acid permease family protein; n=2... 105 3e-21
UniRef50_Q9VJ75 Cluster: CG10413-PA; n=8; Endopterygota|Rep: CG1... 103 2e-20
UniRef50_A6RLT2 Cluster: Putative uncharacterized protein; n=2; ... 102 4e-20
UniRef50_Q19301 Cluster: Putative uncharacterized protein; n=2; ... 100 2e-19
UniRef50_A6GE86 Cluster: Amino acid permease-associated region; ... 99 2e-19
UniRef50_Q9NQR5 Cluster: Cation-chloride cotransporter-interacti... 98 9e-19
UniRef50_A1SVK2 Cluster: Amino acid permease-associated region; ... 97 2e-18
UniRef50_Q8CJI3-2 Cluster: Isoform 2 of Q8CJI3 ; n=2; Rattus nor... 96 4e-18
UniRef50_Q6CFS0 Cluster: Yarrowia lipolytica chromosome B of str... 94 1e-17
UniRef50_A6PMX8 Cluster: Amino acid permease-associated region; ... 94 1e-17
UniRef50_UPI0001555D20 Cluster: PREDICTED: similar to Melanoma-d... 93 2e-17
UniRef50_UPI00015B516A Cluster: PREDICTED: similar to cation chl... 92 4e-17
UniRef50_Q6BML2 Cluster: Debaryomyces hansenii chromosome F of s... 91 8e-17
UniRef50_P38329 Cluster: Uncharacterized membrane protein YBR235... 91 1e-16
UniRef50_UPI00015A4CB0 Cluster: UPI00015A4CB0 related cluster; n... 91 1e-16
UniRef50_Q4RQU3 Cluster: Chromosome 2 SCAF15004, whole genome sh... 91 1e-16
UniRef50_A4AS86 Cluster: Na-K-Cl cotransporter, putative; n=1; F... 88 7e-16
UniRef50_Q2UVJ5 Cluster: Cation chloride cotransporter; n=14; Ma... 86 3e-15
UniRef50_Q6ZP54 Cluster: CDNA FLJ26488 fis, clone KDN05770, high... 86 3e-15
UniRef50_Q4RZ03 Cluster: Chromosome 16 SCAF14974, whole genome s... 80 3e-13
UniRef50_A2E1M7 Cluster: Amino acid permease family protein; n=5... 79 4e-13
UniRef50_UPI0000F207D5 Cluster: PREDICTED: hypothetical protein;... 79 6e-13
UniRef50_Q8THK8 Cluster: Na-K-Cl cotransporter; n=3; cellular or... 75 5e-12
UniRef50_A2FYU8 Cluster: Amino acid permease family protein; n=1... 75 1e-11
UniRef50_Q9H7Q7 Cluster: FLJ00010 protein; n=9; Eutheria|Rep: FL... 72 5e-11
UniRef50_A6DJU2 Cluster: Na-K-Cl cotransporter, putative; n=1; L... 71 9e-11
UniRef50_A1ZYX4 Cluster: Solute carrier family 12 (Potassium/chl... 70 2e-10
UniRef50_Q21977 Cluster: Temporarily assigned gene name protein ... 68 1e-09
UniRef50_Q4T0H4 Cluster: Chromosome undetermined SCAF11052, whol... 67 2e-09
UniRef50_A2DUG3 Cluster: Amino acid permease family protein; n=1... 67 2e-09
UniRef50_Q09573 Cluster: Sodium/chloride cotransporter type 2; n... 64 1e-08
UniRef50_A3IKP0 Cluster: Na-K-Cl cotransporter, putative; n=5; C... 63 3e-08
UniRef50_Q8NF23 Cluster: FLJ00379 protein; n=5; Euteleostomi|Rep... 62 5e-08
UniRef50_O44846 Cluster: Putative uncharacterized protein; n=4; ... 61 1e-07
UniRef50_A7SLI2 Cluster: Predicted protein; n=1; Nematostella ve... 61 1e-07
UniRef50_Q9N5M5 Cluster: Putative uncharacterized protein; n=2; ... 59 5e-07
UniRef50_Q6MD03 Cluster: Putative bumetanide-sensitive Na-K-Cl; ... 58 7e-07
UniRef50_A7Q1C8 Cluster: Chromosome chr10 scaffold_43, whole gen... 58 1e-06
UniRef50_A6R3M7 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-06
UniRef50_UPI00015B4A73 Cluster: PREDICTED: similar to potassium/... 57 2e-06
UniRef50_UPI00015556EE Cluster: PREDICTED: hypothetical protein;... 57 2e-06
UniRef50_A2DFI6 Cluster: Amino acid permease family protein; n=9... 56 3e-06
UniRef50_Q4T7I7 Cluster: Chromosome undetermined SCAF8089, whole... 54 1e-05
UniRef50_UPI0000F1E57D Cluster: PREDICTED: hypothetical protein,... 53 3e-05
UniRef50_Q4T2D9 Cluster: Chromosome undetermined SCAF10292, whol... 53 3e-05
UniRef50_Q9UHW9 Cluster: Solute carrier family 12 member 6; n=14... 52 6e-05
UniRef50_UPI0000E47BA3 Cluster: PREDICTED: hypothetical protein;... 48 7e-04
UniRef50_UPI0000ECA8E1 Cluster: Solute carrier family 12 member ... 46 0.003
UniRef50_Q7PN04 Cluster: ENSANGP00000004794; n=1; Anopheles gamb... 44 0.020
UniRef50_P39282 Cluster: Inner membrane transporter yjeM; n=36; ... 40 0.19
UniRef50_UPI00004984DC Cluster: amino acid transporter; n=1; Ent... 39 0.58
UniRef50_A3W042 Cluster: Amino acid transporter; n=1; Roseovariu... 38 0.77
UniRef50_Q4RZ04 Cluster: Chromosome 16 SCAF14974, whole genome s... 38 1.0
UniRef50_P77400 Cluster: Inner membrane transport protein ybaT; ... 38 1.0
UniRef50_Q6KYY4 Cluster: Amino acid permease; n=2; Thermoplasmat... 38 1.3
UniRef50_Q5C149 Cluster: SJCHGC05139 protein; n=1; Schistosoma j... 37 1.8
UniRef50_A0YCV4 Cluster: Cationic amino acid transporter; n=1; m... 36 3.1
UniRef50_P53388 Cluster: Dicarboxylic amino acid permease; n=11;... 36 3.1
UniRef50_Q89Q78 Cluster: Blr3252 protein; n=1; Bradyrhizobium ja... 36 5.4
UniRef50_A3DCD8 Cluster: Putative uncharacterized protein; n=1; ... 36 5.4
UniRef50_Q875M6 Cluster: DIP5; n=2; Saccharomycetaceae|Rep: DIP5... 36 5.4
UniRef50_Q83CZ7 Cluster: Amino acid permease family protein; n=1... 35 7.1
UniRef50_Q0TRW3 Cluster: Amino acid permease family protein; n=3... 35 7.1
UniRef50_A7TMM7 Cluster: Putative uncharacterized protein; n=1; ... 35 7.1
UniRef50_Q8ZYY0 Cluster: Amino acid permease; n=4; Pyrobaculum|R... 35 7.1
>UniRef50_Q25479 Cluster: Bumetanide-sensitive
sodium-(potassium)-chloride cotransporter; n=8;
Endopterygota|Rep: Bumetanide-sensitive
sodium-(potassium)-chloride cotransporter - Manduca
sexta (Tobacco hawkmoth) (Tobacco hornworm)
Length = 1060
Score = 417 bits (1026), Expect = e-115
Identities = 196/308 (63%), Positives = 236/308 (76%), Gaps = 10/308 (3%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG+YY++SRSLG EFGASVGI+FAFANAVAASMNTIGFCDSLN LL+++GLKI ++ +ND
Sbjct: 188 GGIYYIISRSLGPEFGASVGIIFAFANAVAASMNTIGFCDSLNDLLRSNGLKITEDPIND 247
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
+RIVG VALLVMC+ICAIGMDWE+KAQNFL G ++GP + E AKGFV
Sbjct: 248 VRIVGTVALLVMCIICAIGMDWESKAQNFLIAIIVGAMVDFVVGTIMGPKDNSEIAKGFV 307
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G++ T EN+ +FR+SE + +FFSVFA++FP+VTG+QAGANI GDLK+PA AIPKGT
Sbjct: 308 GLSSATFVENFKSDFRFSEKLDQNFFSVFAIFFPSVTGIQAGANISGDLKDPASAIPKGT 367
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANL----------TTAALESCKPHCGYGLH 236
LLAL IS+ SY MV+ +G GALRDASGN+ +L ++ +L + C YGLH
Sbjct: 368 LLALLISMVSYTLMVLFAGGGALRDASGNITDLLIVNGTVTDYSSVSLCALNNTCEYGLH 427
Query: 237 NNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGR 296
N+Y++MQLMSAWGPFIY GCW VPRLIQALGVDRIYPGLIFFSKPYGR
Sbjct: 428 NSYSVMQLMSAWGPFIYGGCWAATLSTALTNLLSVPRLIQALGVDRIYPGLIFFSKPYGR 487
Query: 297 HGEPYRGY 304
HGEPYRGY
Sbjct: 488 HGEPYRGY 495
Score = 158 bits (383), Expect = 6e-37
Identities = 80/174 (45%), Positives = 111/174 (63%), Gaps = 3/174 (1%)
Query: 595 VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIE 654
+D WWLY+DGGL ILLPYII++R LRIFA+ H+ E E + M +LL KFRI+
Sbjct: 883 LDVWWLYDDGGLTILLPYIISQRSAWANCKLRIFALANRLHEMELEERNMANLLAKFRID 942
Query: 655 YTELTLVRGIGDAPPESSWKMFNNIINDFKSEEKT-DILTSEAELKSQYSKTSXXXXXXX 713
Y+ LT+V+ I D P + +F+ I F E + D S+ EL++ KT+
Sbjct: 943 YSSLTMVQDITDPPQPETKALFDETIKKFTEESASPDCRISDMELQTLAVKTNRQLRLRE 1002
Query: 714 XXXQHSTKAAIVIITLPLPRK--VSASLYMAWLEVLSRDLPPVLFVRGNDSCVL 765
+S A +V+++LP+PRK +SA LYMAWLE++SRDLPP+LFVRGN + VL
Sbjct: 1003 LLLANSKDARLVVMSLPMPRKGSISAPLYMAWLEMMSRDLPPMLFVRGNHTSVL 1056
Score = 155 bits (376), Expect = 4e-36
Identities = 73/168 (43%), Positives = 110/168 (65%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
DV+WGSST+ Q Y+ +S L+ H ++Y PQLLVLAG P RPAL+D+ ++++K
Sbjct: 595 DVNWGSSTQAQMYKTALSSAHALARTGEHVKNYWPQLLVLAGRPQARPALVDLGNLISKA 654
Query: 378 GSFMIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
GS MIV DI+ L+ R +R +++++ RK+RAF + G + GA AL+Q SG+
Sbjct: 655 GSLMIVGDISQEKLSYKVRSARARSDDEWLRGRKVRAFCSRVHGFSFEPGARALVQGSGV 714
Query: 438 GKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRVPG 485
G+L+PN+LL+G+K DWT + Y+ V+ AF+ +LAV I+RV G
Sbjct: 715 GRLAPNVLLMGYKSDWTTCPANDLVSYFNVLHTAFENRLAVAIVRVSG 762
>UniRef50_Q16UI2 Cluster: Kidney-specific Na-K-Cl cotransport
protein splice isoform A, putative; n=5;
Endopterygota|Rep: Kidney-specific Na-K-Cl cotransport
protein splice isoform A, putative - Aedes aegypti
(Yellowfever mosquito)
Length = 1027
Score = 384 bits (946), Expect = e-105
Identities = 177/301 (58%), Positives = 221/301 (73%), Gaps = 3/301 (0%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG+YY++SRSLG EFGASVG++FAFAN+V ASMNTIGFC SLN LL ++G+KI+D VND
Sbjct: 188 GGIYYIISRSLGPEFGASVGVVFAFANSVNASMNTIGFCSSLNDLLASYGIKIIDGGVND 247
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRIVG +AL+VM ICA+GMDWE KAQNFL GA++GPSSDV+RA+GF+
Sbjct: 248 IRIVGTIALIVMVAICAVGMDWEVKAQNFLLVAILVAIGAFAVGAIMGPSSDVDRARGFL 307
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G + + + N +R+SEG + +FFSVFA++FP+VTG+Q+GANICGDLK+PA AIPKGT
Sbjct: 308 GFSTEVVSSNMGSLYRFSEGIQQNFFSVFAIFFPSVTGIQSGANICGDLKDPASAIPKGT 367
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKP---HCGYGLHNNYAIMQ 243
LLA +S SY + +G A+RDASGN+ +L SC +C YGL+N+YAIMQ
Sbjct: 368 LLACLVSAISYVIFALFAGGVAVRDASGNLTDLVGVNFTSCDTVLNNCKYGLNNDYAIMQ 427
Query: 244 LMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYRG 303
L++A IY GCW VPRLIQALG+DRIYPGLIFFSK YG+H EPYRG
Sbjct: 428 LIAASSMLIYIGCWAATLSTALTNLLSVPRLIQALGIDRIYPGLIFFSKGYGKHSEPYRG 487
Query: 304 Y 304
Y
Sbjct: 488 Y 488
Score = 268 bits (656), Expect = 5e-70
Identities = 154/450 (34%), Positives = 239/450 (53%), Gaps = 16/450 (3%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
DV+WGSST+ Y+ ++ L H ++YNPQLLVL+G PL RP L++ A+++TK
Sbjct: 588 DVNWGSSTQAAAYKSALNSALNLEQVDDHVKNYNPQLLVLSGNPLHRPNLLNFANLITKN 647
Query: 378 GSFMIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
S MIV ++ + L ER + G++ +K K++AFY +L GL A++Q++G
Sbjct: 648 QSLMIVGNVVEEKLNYKERKAYIQSGKKVLKDLKIKAFYSVLDGLPFDESVRAMIQSTGF 707
Query: 438 GKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRVPGTSQTVQRWRWTP 497
G+LSPNIL++G+K+DW + ++ YY ++ +AFD +LA+TILR+P +
Sbjct: 708 GRLSPNILMVGYKQDWRTCGNAELHSYYNILHNAFDNRLALTILRLPNGLDC------SH 761
Query: 498 RVVSEPNNFELVMHTQVLALMNXXXXXXXXXXXXXXXXXXXXXXXNQLSNETSSSEQNPE 557
V +P L + L +M+ L SSEQ
Sbjct: 762 LVPPKP---ALDLADSALNIMSSMAYINTPQGLRIQKGLMPVNSNLDLHGMAPSSEQISV 818
Query: 558 SIGGEALRSANFSRTSRRKLSNGALSFRALSFNCKQYVDAWWLYEDGGLNILLPYIIARR 617
++ EA N + S FR Y+D WWLY+DGGL ILLPYII+ R
Sbjct: 819 NVPNEA--QDNKTTPEAAAPSQELNIFR--EKQPAGYIDVWWLYDDGGLTILLPYIISTR 874
Query: 618 GYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIEYTELTLVRGIGDAPPESSWKMFN 677
+ +R+FA+ +Q E E + M LL+K RI Y L +V + D P E++ +
Sbjct: 875 SKWSECQIRVFALATQQTNVEEERENMTILLEKLRINYVSLIMVT-LSDKPQEATIQSHK 933
Query: 678 NIINDFKSEEKTDILTSEAELKSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLPRK--V 735
++ ++TD+ S +E KT Q+S A+++++++P+PRK V
Sbjct: 934 ALLGTLVEGQETDVFVSASEQAQLEEKTYRQLRLRELLQQYSKNASLIVLSMPIPRKGIV 993
Query: 736 SASLYMAWLEVLSRDLPPVLFVRGNDSCVL 765
SA LYM+WLE+L++D+PP L VRGN + VL
Sbjct: 994 SAPLYMSWLEMLTKDMPPFLLVRGNQTSVL 1023
>UniRef50_Q9VTW8 Cluster: CG4357-PA, isoform A; n=9; Coelomata|Rep:
CG4357-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 1171
Score = 301 bits (738), Expect = 6e-80
Identities = 135/302 (44%), Positives = 198/302 (65%), Gaps = 4/302 (1%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YY++SRSLG EFG S+G++F+ ANAVA +M +GFC+S+ ++ T G +I+D V D
Sbjct: 277 GGTYYMISRSLGPEFGGSIGLIFSLANAVACAMYVVGFCESMLAMMTTFGWEIIDGGVQD 336
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
+RI+G + +L++ +I +GM+WE KAQ L G+ IGP SD E AKGF+
Sbjct: 337 VRIIGCITILLLLIIVVVGMEWEAKAQIGLLIILLVAIGDFVIGSFIGPKSDAEMAKGFL 396
Query: 127 GINLQTIRENWLPNFRYSEGR-EHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKG 185
G N + N ++R +G +HDFFSVFA++FPA TG+ AGANI GDLK+P +IPKG
Sbjct: 397 GYNATLFKNNLFADYRPEKGGIQHDFFSVFAIFFPAATGILAGANISGDLKDPQKSIPKG 456
Query: 186 TLLALAISVTSYFTMVILSGMGALRDASGNVANLT--TAALESCKP-HCGYGLHNNYAIM 242
T+LA+ I+ +Y MV+ G RDA+GN++++ T A C+P C YGL N++ ++
Sbjct: 457 TILAIVITTGTYLIMVLQCGATVARDATGNLSDVVNGTFAFLDCQPGECNYGLQNSFQVI 516
Query: 243 QLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYR 302
+L+SA+GP IYAGC+ P++ QAL D +YP +++F+K YG++ EP R
Sbjct: 517 ELVSAFGPLIYAGCYAATLSSALASLVSAPKVFQALCKDELYPKIVWFAKGYGKNNEPVR 576
Query: 303 GY 304
GY
Sbjct: 577 GY 578
Score = 159 bits (385), Expect = 3e-37
Identities = 84/187 (44%), Positives = 114/187 (60%), Gaps = 16/187 (8%)
Query: 595 VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIE 654
+D WWLY+DGGL +LLPYII+ R LR++A+ + + EFE + M SLL KFRI+
Sbjct: 981 IDVWWLYDDGGLTLLLPYIISTRRTWQSCKLRVYALANKNSELEFEQRSMASLLSKFRID 1040
Query: 655 YTELTLVRGIGDAPPESSWKMFNNIINDFKSEEKT--------------DILTSEAELKS 700
Y++LTL+ I P E+S + FN +I DF EK D L ++ +L +
Sbjct: 1041 YSDLTLIPDITKKPQETSTQFFNELIKDFVVTEKDGENGTSSRATLNEDDALITDDDLLA 1100
Query: 701 QYSKTSXXXXXXXXXXQHSTKAAIVIITLPLPRK--VSASLYMAWLEVLSRDLPPVLFVR 758
KT+ + STK+ +V++TLP+PRK VSA LYMAWLE LSRD+PP LFVR
Sbjct: 1101 VQDKTNRYLRLREYLREQSTKSDLVVMTLPMPRKNIVSAPLYMAWLESLSRDMPPFLFVR 1160
Query: 759 GNDSCVL 765
GN + VL
Sbjct: 1161 GNQTSVL 1167
Score = 151 bits (367), Expect = 5e-35
Identities = 66/167 (39%), Positives = 108/167 (64%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
DV+WGS+T+ Q Y++ + + +L++ H ++Y PQ+LVL+G P RP L+D+A+MLTK
Sbjct: 678 DVNWGSTTQAQTYKNALMSVQQLNNVEEHVKNYRPQILVLSGLPNTRPVLVDLAYMLTKN 737
Query: 378 GSFMIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
S ++ + + ++ R Q + + +++ FY L+ G D + G ALMQA+G+
Sbjct: 738 LSLLVCGHVLKGSSSQKYRTYLQERAGNWFRKHRVKGFYALVDGEDFESGTRALMQATGI 797
Query: 438 GKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRVP 484
GKL PNI+L+G+K DW +HK++ Y+ V+ A D+ L+V ILRVP
Sbjct: 798 GKLKPNIILMGYKTDWQTCDHKELDQYFNVMHKALDMYLSVAILRVP 844
>UniRef50_Q9U6A3 Cluster: Na+/K+/2Cl-cotransporter; n=3;
Heterotremata/Thoracotremata group|Rep:
Na+/K+/2Cl-cotransporter - Callinectes sapidus (Blue
crab)
Length = 1031
Score = 272 bits (667), Expect = 2e-71
Identities = 136/320 (42%), Positives = 193/320 (60%), Gaps = 20/320 (6%)
Query: 5 ERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTH--GLKIVDN 62
+ GGVYY++SRSLG EFG S+G++F AN++AA+ IGFCDSL L+ + G KIVD
Sbjct: 153 QAGGVYYMISRSLGPEFGGSIGLMFTLANSIAAATYIIGFCDSLKDLMFYYFDGAKIVDG 212
Query: 63 DVNDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERA 122
VND RIVG + L+ + + +GMDW T+ Q L GA IGP D++R+
Sbjct: 213 AVNDTRIVGTITLICVLALAIVGMDWVTRVQMGLLFLLIGSQIDFVVGAFIGPQDDLQRS 272
Query: 123 KGFVGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAI 182
+GF+G + + + +N P++R E R +FFSVF V+F AVTG+ AGAN+ GDLK+PA AI
Sbjct: 273 QGFIGFSGEVMAKNVGPDYRDFENRGQNFFSVFGVFFTAVTGIVAGANLSGDLKDPADAI 332
Query: 183 PKGTLLALAISVTSYFTMVILSGMGALRDASGN-----------------VANLT-TAAL 224
PKGTL A+ + +Y I+ G LRDA+G+ N + T ++
Sbjct: 333 PKGTLAAILTTFCTYIIYPIMIGAAVLRDATGDKDVYLMYQNHSIDENPAFTNCSLTGSV 392
Query: 225 ESCKPHCGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIY 284
++ C +GL N++ +M+LMSAWGP IYAGC+ PR++QAL D++Y
Sbjct: 393 DNGTQVCKFGLQNSFQVMELMSAWGPLIYAGCFAATLSSAIASLVGAPRVLQALAKDKLY 452
Query: 285 PGLIFFSKPYGRHGEPYRGY 304
PG+ FSK G + +P RGY
Sbjct: 453 PGIFMFSKGTGANNDPVRGY 472
Score = 249 bits (610), Expect = 2e-64
Identities = 150/459 (32%), Positives = 229/459 (49%), Gaps = 14/459 (3%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
+V+WGSST+ Q Y + +L+ H ++Y PQ+LVL G RP LID ++ +TK
Sbjct: 572 NVNWGSSTQAQTYVSALKTALDLNTIEEHVKNYRPQILVLTGPVGSRPPLIDFSYSITKN 631
Query: 378 GSFMIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
S + + T+ R S ++ +RAFY L++G L+ GA L Q GL
Sbjct: 632 ISLLACGHVIQGPQTQRLRNSLTRQSYNWLTRHSIRAFYSLVEGSTLEDGARNLFQLVGL 691
Query: 438 GKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRVPGTSQTVQRWRWTP 497
GKL PN +++G+K +W E K++ Y+ + +A D+ V ILRVP Q
Sbjct: 692 GKLRPNTVVLGYKANWRKCEPKELKAYFNTLHEALDMYFGVVILRVPQGLDYSQIIEDED 751
Query: 498 RVVSEPNNFELVMHTQVLALMNXXXXXXXXXXXXXXXXXXXXXXXNQLSNETSSSEQNPE 557
++ N + TQ Q+ + + N E
Sbjct: 752 SPITMNGNEGAI--TQTTDDKPGQSSANQLTQDGTDSEASSPPGSPQVERSAAVVDANGE 809
Query: 558 SIGGEALRSANFSR-TSRRKLSNGALSFRALSFNCKQY---VDAWWLYEDGGLNILLPYI 613
+ AN R +LS L+ F KQ +D WWLY+DGGL +L+PYI
Sbjct: 810 NSKKRRTSLANLFRGPGGSELSKDVLN-NITMFKRKQKKGTIDVWWLYDDGGLTLLVPYI 868
Query: 614 IARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIEYTELTLVRGIGDAPPESSW 673
+ R LR+FA+ + + + E + M +LL KFRI+Y+++ ++ + ESS
Sbjct: 869 LTTRSQWSGCKLRVFALANRKDELDMEQRSMANLLAKFRIDYSDVIVIPDVAKKAAESSR 928
Query: 674 KMFNNIINDFKSEEKTD-----ILTSEAELKSQYSKTSXXXXXXXXXXQHSTKAAIVIIT 728
F+ +I DFK++++ D +L SEAEL Q KT+ ++S + +V++T
Sbjct: 929 MEFDQLIEDFKTKDEVDKESDGLLISEAELLGQREKTNRHIRLRELLLENSRDSTLVVMT 988
Query: 729 LPLPRK--VSASLYMAWLEVLSRDLPPVLFVRGNDSCVL 765
LP+PRK VSA LYMAWLE L+RD+PP L +RGN + VL
Sbjct: 989 LPMPRKTSVSAPLYMAWLETLTRDMPPFLLIRGNQTSVL 1027
>UniRef50_P55011 Cluster: Solute carrier family 12 member 2
(Bumetanide-sensitive sodium- (potassium)-chloride
cotransporter 1); n=86; Gnathostomata|Rep: Solute
carrier family 12 member 2 (Bumetanide-sensitive sodium-
(potassium)-chloride cotransporter 1) - Homo sapiens
(Human)
Length = 1212
Score = 248 bits (606), Expect = 6e-64
Identities = 132/313 (42%), Positives = 182/313 (58%), Gaps = 22/313 (7%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG ++G++FAFANAVA +M +GF +++ LLK H + ++D ++ND
Sbjct: 350 GGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMID-EIND 408
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRI+GA+ ++++ I GM+WE KAQ L G I S ++ KGF
Sbjct: 409 IRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLES--KKPKGFF 466
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G + EN+ P+FR E FFSVFA++FPA TG+ AGANI GDL +P AIPKGT
Sbjct: 467 GYKSEIFNENFGPDFR----EEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGT 522
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNV--------ANLTTAA------LESCKPH-C 231
LLA+ I+ Y + + G +RDA+GNV N T+AA SC+ C
Sbjct: 523 LLAILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPC 582
Query: 232 GYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFS 291
YGL NN+ +M ++S + P I AG + P++ QAL D IYP F+
Sbjct: 583 SYGLMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFA 642
Query: 292 KPYGRHGEPYRGY 304
K YG++ EP RGY
Sbjct: 643 KGYGKNNEPLRGY 655
Score = 119 bits (287), Expect = 3e-25
Identities = 60/168 (35%), Positives = 94/168 (55%), Gaps = 2/168 (1%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
DV+WGSST+ Y + + LS H +++ PQ LV+ G P RPAL+ + H TK
Sbjct: 755 DVNWGSSTQALTYLNALQHSIRLSGVEDHVKNFRPQCLVMTGAPNSRPALLHLVHDFTKN 814
Query: 378 GSFMIVADITDTALTKG--ERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQAS 435
MI + + E Q ++++ K++AFY + DL+ GA LMQA+
Sbjct: 815 VGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAA 874
Query: 436 GLGKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRV 483
GLG++ PN L++GFKKDW A+ + + Y + DAFD++ V ++R+
Sbjct: 875 GLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRL 922
Score = 115 bits (277), Expect = 4e-24
Identities = 64/189 (33%), Positives = 108/189 (57%), Gaps = 16/189 (8%)
Query: 592 KQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKF 651
K +D WWL++DGGL +L+PY++ + +R+F I + ++ + + + M +LL KF
Sbjct: 1021 KNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVF-IGGKINRIDHDRRAMATLLSKF 1079
Query: 652 RIEYTELTLVRGIGDAPPESSWKMFNNIINDFKSEE---KTDILT----------SEAEL 698
RI+++++ ++ I P + + F II ++ E + DI ++ EL
Sbjct: 1080 RIDFSDIMVLGDINTKPKKENIIAFEEIIEPYRLHEDDKEQDIADKMKEDEPWRITDNEL 1139
Query: 699 KSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLPRK--VSASLYMAWLEVLSRDLPPVLF 756
+ +KT +HS+ A I++++LP+ RK VS++LYMAWLE LS+DLPP+L
Sbjct: 1140 ELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILL 1199
Query: 757 VRGNDSCVL 765
VRGN VL
Sbjct: 1200 VRGNHQSVL 1208
>UniRef50_A7S4G9 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 975
Score = 242 bits (593), Expect = 2e-62
Identities = 127/306 (41%), Positives = 176/306 (57%), Gaps = 13/306 (4%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG S+G++F+ ANAVA ++ +GF +++ +L+ +G I+D +VND
Sbjct: 139 GGAYYLISRSLGPEFGGSIGLIFSLANAVAVALYVVGFAETVRDILRENGSLIID-EVND 197
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IR++G +++L + + IG++W + Q L G+ IGP + A+G V
Sbjct: 198 IRVIGVISVLALLAVTLIGLEWVVRTQMVLLGILLISIVDAIVGSFIGPQDKLSVAQGIV 257
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G+N +T N LP++R E FFSVFAV+FPA TG+ AG NI GDLK+ AIPKGT
Sbjct: 258 GLNAKTFTTNLLPDYRPGE----HFFSVFAVFFPAATGILAGVNISGDLKDAQKAIPKGT 313
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNV-------ANLTTAALESCK-PHCGYGLHNN 238
L A+ +S Y + L+G LRDASG V AN+T A SC C YGL N+
Sbjct: 314 LWAILLSTLVYIALAWLAGACILRDASGFVETVVNATANVTMATPPSCPGSGCLYGLIND 373
Query: 239 YAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHG 298
Y M+ MSAWGP + G + P+ QAL D I+P + +F G
Sbjct: 374 YQAMEKMSAWGPLVTCGIFAATLSSALASLVGAPKTFQALCKDNIFPYIGYFGIGVGPGE 433
Query: 299 EPYRGY 304
EP RGY
Sbjct: 434 EPRRGY 439
Score = 121 bits (291), Expect = 8e-26
Identities = 59/166 (35%), Positives = 94/166 (56%), Gaps = 6/166 (3%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
+V+WGSS + Y + F L++ H +++ PQ LVL G P RP L + +TK
Sbjct: 539 EVNWGSSAQAFTYIQALRFAYRLNNTEDHVKNFRPQCLVLTGAPSSRPNLTYIVSQITKN 598
Query: 378 GSFMIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
M+ + +L + V + + +++ RK+RAF+ + L+ G +L+Q +GL
Sbjct: 599 VGLMVCGQVNVGSLCQ---VKSE---KDWLRERKIRAFHTVCSAASLRDGVQSLLQTAGL 652
Query: 438 GKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRV 483
GKL PN L+IGFK++W A H ++ +Y +I DAF+L V ILRV
Sbjct: 653 GKLKPNTLVIGFKRNWMRAPHSEVEEYVNIINDAFELNYGVAILRV 698
Score = 111 bits (267), Expect = 7e-23
Identities = 72/200 (36%), Positives = 108/200 (54%), Gaps = 17/200 (8%)
Query: 571 RTSRRKLSNGALS-FRALSFNCKQY--VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRI 627
+TS+ + S+ S R+++F KQ VD WWL++DGGL IL+PY++ LRI
Sbjct: 784 QTSQVRFSSEPSSTLRSVTFKGKQKGTVDVWWLFDDGGLTILIPYLLTLHSLWKGCRLRI 843
Query: 628 FAITKEQHKREFENKCMESLLKKFRIEYTELTLVRGIGDAPPESSWKMFNNIINDFKSEE 687
F K E + M +LLKKFRI+++ + +V GI AP S + DF+
Sbjct: 844 FTPGSSNIKNN-EIR-MANLLKKFRIDFSSIEVVHGIDKAPSNKS-------VQDFRRLP 894
Query: 688 KTDILTSEAELKSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLPRK--VSASLYMAWLE 745
+ L +L + + QHS A ++++TLP+P+ +S +YM+WLE
Sbjct: 895 IKEELDEGVQLDKRILRQ---IRIGELLRQHSKDARLIVMTLPVPKPTLMSPLMYMSWLE 951
Query: 746 VLSRDLPPVLFVRGNDSCVL 765
VLS DLPPV +RGN + VL
Sbjct: 952 VLSADLPPVFLIRGNQTSVL 971
>UniRef50_Q91412 Cluster: Basolateral Na(+)-K(+)-Cl-cotransporter
isoform BSC2; n=6; Bilateria|Rep: Basolateral
Na(+)-K(+)-Cl-cotransporter isoform BSC2 - Necturus
maculosus (Mudpuppy) (Waterdog)
Length = 385
Score = 236 bits (578), Expect = 1e-60
Identities = 128/313 (40%), Positives = 184/313 (58%), Gaps = 22/313 (7%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG ++G++FAFANAVA +M +GF +++ LLK + + ++D+ +ND
Sbjct: 50 GGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFSETVVDLLKENNVVMMDH-MND 108
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRI+GA+ ++V+ I GM+WETKAQ L G I P D ++ KGF
Sbjct: 109 IRIIGAITIVVLLGISVAGMEWETKAQFVLLVILLLAIADFLIGTFI-PLED-KKPKGFF 166
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G + EN+ P+FR E FF+VFA++FPA TG+ AGANI GDL +P +AIPKGT
Sbjct: 167 GYKPEIFSENFGPDFRDDE----TFFTVFAIFFPAATGILAGANISGDLADPQMAIPKGT 222
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGN--------VANLTTAA------LESCK-PHC 231
+LA+ I+ Y + + G +RD +G+ ++N T AA SC+ C
Sbjct: 223 MLAILITTVVYVGIAVSVGSCVVRDPTGSLNDTILTELSNCTEAACKXNFDFSSCRMSQC 282
Query: 232 GYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFS 291
GL ++ +M ++S + P I AG + P++ QAL +D IYPGL F
Sbjct: 283 KXGLMKDFQVMSMVSGFAPLISAGIFSATLSSALASLVSAPKVFQALCIDNIYPGLQMFG 342
Query: 292 KPYGRHGEPYRGY 304
K YG++ EP RGY
Sbjct: 343 KGYGKNNEPLRGY 355
>UniRef50_A7RG55 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 918
Score = 228 bits (558), Expect = 4e-58
Identities = 118/308 (38%), Positives = 173/308 (56%), Gaps = 16/308 (5%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG S+GI+F+ A+AVA +M +GF +++ LLK +G IVD +VND
Sbjct: 137 GGAYYLISRSLGPEFGGSIGIIFSIASAVAVAMYVVGFAETVRDLLKENGALIVD-EVND 195
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
+RI+G + ++ + + +G+ W + Q L G IGP + +A+GF+
Sbjct: 196 VRIIGLITIVFILAVALVGLKWVVRTQVILLAVLIISILDVIIGTFIGPQNASSKAQGFL 255
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G + N++P+FR EG FFSVFA++FPA TG+ AG NI GDLKNP A+PKGT
Sbjct: 256 GYQDGVFQTNFMPDFR-GEG----FFSVFAIFFPAATGILAGVNISGDLKNPHTAVPKGT 310
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANL---------TTAALESCKP-HCGYGLH 236
LLA+ +S Y + L G RDA+G V ++ ++ +C C +GL+
Sbjct: 311 LLAILVSSLVYIVLAWLIGATYARDATGLVMSVAVVNGSSQSNVTSIPTCDTMKCLFGLY 370
Query: 237 NNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGR 296
+ MQ S WGP + AG + P+ QA+ D+++P + +F YG
Sbjct: 371 FDNQAMQKASGWGPIVTAGIFASTLSSAIASIVGAPKTFQAVCKDKLFPKIDYFGVGYGP 430
Query: 297 HGEPYRGY 304
EP RGY
Sbjct: 431 GNEPKRGY 438
Score = 116 bits (279), Expect = 2e-24
Identities = 59/168 (35%), Positives = 92/168 (54%), Gaps = 5/168 (2%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
+V+WGSS + Y + F T L H +++ PQ LVL+G P +RP L+ +A LTK
Sbjct: 538 NVNWGSSGQANTYMSALRFTTLLDTHEEHVKNFRPQCLVLSGRPAERPDLMYIASQLTKN 597
Query: 378 GSFMIVADITDTALTKGERVSRQHIGE--QFVKYRKLRAFYVLLQGLDLKRGANALMQAS 435
M+ ++ K +++S E +++K K++AF L+ G A++ +
Sbjct: 598 SGLMMYGNV---CRQKFDKISDDEEREDAKWLKEHKIKAFRATTTAHSLRTGVQAMLHLT 654
Query: 436 GLGKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRV 483
GLGK+ PN L++GFK DW A + Y+GVI DAF + V ILR+
Sbjct: 655 GLGKMKPNTLVLGFKNDWQIAPLADLEGYFGVINDAFQMDFGVAILRI 702
Score = 99.5 bits (237), Expect = 3e-19
Identities = 64/184 (34%), Positives = 92/184 (50%), Gaps = 15/184 (8%)
Query: 587 LSFNCKQY--VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAI-TKEQHKREFENKC 643
L+F KQ +D WWLY+DGGL ILLPY++ LR+F + + +H + +
Sbjct: 741 LAFEGKQRGTIDVWWLYDDGGLTILLPYLLTLHRLWRSCDLRLFYLDIRSKHAIKADQLK 800
Query: 644 MESLLKKFRIEYTELTLVRGIGDAPPESSWKMFNNIINDFKSEEKTDILTSEAELKSQYS 703
M +L+KKFRI+ + + V G AP S F + E D +
Sbjct: 801 MANLMKKFRIQVSSVVQVPGANTAPSGESLDAFRALP---VGRELDDGPIDD-------K 850
Query: 704 KTSXXXXXXXXXXQHSTKAAIVIITLPLP--RKVSASLYMAWLEVLSRDLPPVLFVRGND 761
K + S A +V+I+LP+P + +YM+WLE+LS+DLPPVL VRGN
Sbjct: 851 KVLRTIRIGELVRKRSNNAKLVVISLPVPVAEMTTPLMYMSWLEMLSKDLPPVLLVRGNQ 910
Query: 762 SCVL 765
VL
Sbjct: 911 RSVL 914
>UniRef50_P59158 Cluster: Solute carrier family 12 member 3; n=13;
Tetrapoda|Rep: Solute carrier family 12 member 3 - Mus
musculus (Mouse)
Length = 1002
Score = 228 bits (558), Expect = 4e-58
Identities = 124/314 (39%), Positives = 179/314 (57%), Gaps = 21/314 (6%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG Y+L+SRSLG E G S+G++FAFANAV +M+T+GF +++ LL+ +G IVD +ND
Sbjct: 199 GGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGFAETVRDLLQEYGTPIVD-PIND 257
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRI+G V + V+ I GM+WE+KAQ G LI P+S+ + +KGF
Sbjct: 258 IRIIGVVTVTVLLAISLAGMEWESKAQVLFFLVIMVSFANYLVGTLI-PASEDKASKGFY 316
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
+ +N +P++R +G FF +F+++FP+ TG+ AGANI GDLK+PAVAIPKGT
Sbjct: 317 SYHGDIFVQNLVPDWRGIDG---SFFGMFSIFFPSATGILAGANISGDLKDPAVAIPKGT 373
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESC----------------KPH 230
L+A+ + SY + G +RDASG+V + T C +
Sbjct: 374 LMAIFWTTISYLAISATIGSCVVRDASGDVNDTMTPGPGPCEGLACGYGWNFTECSQQRS 433
Query: 231 CGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFF 290
C YGL N Y M ++SA+ P I AG + ++ Q L D++YP + FF
Sbjct: 434 CRYGLINYYQTMSMVSAFAPLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFF 493
Query: 291 SKPYGRHGEPYRGY 304
K YG++ EP RGY
Sbjct: 494 GKGYGKNREPVRGY 507
Score = 119 bits (287), Expect = 3e-25
Identities = 62/170 (36%), Positives = 96/170 (56%), Gaps = 6/170 (3%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
+V+WGSS + Y +S+ L+ H ++Y PQ LVL G P RPAL+D T+
Sbjct: 607 EVNWGSSVQAGSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVSTFTQN 666
Query: 378 GSFMIVADIT----DTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQ 433
S MI + + + ++ H +++ RK++AFY + DL+ G LMQ
Sbjct: 667 LSLMICGHVLIGPGKQRVPELRLIASGHT--KWLNKRKIKAFYSDVIAEDLRSGVQILMQ 724
Query: 434 ASGLGKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRV 483
ASGLG++ PNIL++GFK++W +A + DY GV+ DAFD V ++R+
Sbjct: 725 ASGLGRMKPNILVVGFKRNWQSAHPATVEDYIGVLHDAFDFNYGVCVMRM 774
Score = 105 bits (253), Expect = 3e-21
Identities = 67/190 (35%), Positives = 104/190 (54%), Gaps = 17/190 (8%)
Query: 592 KQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKF 651
K+ +D +WL++DGGL +L+PY++ R+ K +R+F + + ++ + E K + SLL KF
Sbjct: 809 KKTIDIYWLFDDGGLTLLIPYLLHRKKRWGKCKIRVF-VGGQINRMDEERKAIISLLSKF 867
Query: 652 RIEYTELTLVRGIGDAPPESSWKMFNNII-----ND-FKSEEKTDIL-------TSEAEL 698
R+ + E+ ++ I P K F ++I ND FK E + S+ E+
Sbjct: 868 RLGFHEVHVLPDINQKPQAEHTKRFEDMIAPFRLNDGFKDEATVTEMRRDCPWKISDEEI 927
Query: 699 KSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLPR--KVSASLYMAWLEVLSRDL-PPVL 755
K+ +S AA++I+TLP+ R K +SLYMAWLE LS+DL PPVL
Sbjct: 928 NKNRIKSLRQVRLSEILLDYSRDAALIILTLPIGRKGKCPSSLYMAWLETLSQDLRPPVL 987
Query: 756 FVRGNDSCVL 765
+RGN VL
Sbjct: 988 LIRGNQENVL 997
>UniRef50_P55017 Cluster: Solute carrier family 12 member 3; n=45;
Euteleostomi|Rep: Solute carrier family 12 member 3 -
Homo sapiens (Human)
Length = 1021
Score = 228 bits (558), Expect = 4e-58
Identities = 123/314 (39%), Positives = 178/314 (56%), Gaps = 21/314 (6%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG Y+L+SRSLG E G S+G++FAFANAV +M+T+GF +++ LL+ +G IVD +ND
Sbjct: 201 GGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGFAETVRDLLQEYGAPIVD-PIND 259
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRI+G V++ V+ I GM+WE+KAQ G LI PS D + +KGF
Sbjct: 260 IRIIGVVSVTVLLAISLAGMEWESKAQVLFFLVIMVSFANYLVGTLIPPSED-KASKGFF 318
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
+N +P++R +G FF +F+++FP+ TG+ AGANI GDLK+PA+AIPKGT
Sbjct: 319 SYRADIFVQNLVPDWRGPDGT---FFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGT 375
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESC---------------KPH- 230
L+A+ + SY + G +RDASG + + T +C + H
Sbjct: 376 LMAIFWTTISYLAISATIGSCVVRDASGVLNDTVTPGWGACEGLACSYGWNFTECTQQHS 435
Query: 231 CGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFF 290
C YGL N Y M ++S + P I AG + ++ Q L D++YP + FF
Sbjct: 436 CHYGLINYYQTMSMVSGFAPLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFF 495
Query: 291 SKPYGRHGEPYRGY 304
K YG++ EP RGY
Sbjct: 496 GKGYGKNKEPVRGY 509
Score = 122 bits (293), Expect = 5e-26
Identities = 64/169 (37%), Positives = 94/169 (55%), Gaps = 4/169 (2%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
+V+WGSS + Y +S+ L+ H ++Y PQ LVL G P RPAL+D T+
Sbjct: 609 EVNWGSSVQAGSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVGTFTRN 668
Query: 378 GSFMIVADITDTALTKGERVSRQHIGEQFVKY---RKLRAFYVLLQGLDLKRGANALMQA 434
S MI + K Q I K+ RK++AFY + DL+RG LMQA
Sbjct: 669 LSLMICGHVL-IGPHKQRMPELQLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQA 727
Query: 435 SGLGKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRV 483
+GLG++ PNIL++GFKK+W +A + DY G++ DAF+ V ++R+
Sbjct: 728 AGLGRMKPNILVVGFKKNWQSAHPATVEDYIGILHDAFEFNYGVCVMRM 776
Score = 106 bits (254), Expect = 3e-21
Identities = 66/190 (34%), Positives = 105/190 (55%), Gaps = 17/190 (8%)
Query: 592 KQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKF 651
K+ +D +WL++DGGL +L+PY++ R+ K +R+F + + ++ + E K + SLL KF
Sbjct: 828 KKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKCKIRVF-VGGQINRMDQERKAIISLLSKF 886
Query: 652 RIEYTELTLVRGIGDAPPESSWKMFNNII-----ND-FKSEEKTDIL-------TSEAEL 698
R+ + E+ ++ I P K F ++I ND FK E + + S+ E+
Sbjct: 887 RLGFHEVHILPDINQNPRAEHTKRFEDMIAPFRLNDGFKDEATVNEMRRDCPWKISDEEI 946
Query: 699 KSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLPR--KVSASLYMAWLEVLSRDL-PPVL 755
K+ +S AA+++ITLP+ R K +SLYMAWLE LS+DL PPV+
Sbjct: 947 TKNRVKSLRQVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYMAWLETLSQDLRPPVI 1006
Query: 756 FVRGNDSCVL 765
+RGN VL
Sbjct: 1007 LIRGNQENVL 1016
>UniRef50_Q1LX46 Cluster: Novel protein similar to vertebrate solute
carrier family 12 (Sodium/chloride transporters), member
3; n=2; Euteleostomi|Rep: Novel protein similar to
vertebrate solute carrier family 12 (Sodium/chloride
transporters), member 3 - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 1012
Score = 223 bits (544), Expect = 2e-56
Identities = 120/314 (38%), Positives = 178/314 (56%), Gaps = 21/314 (6%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG Y+L+SRSLG E G S+G++FAFANAVA +M+T+GF +++ L++ + +VD +ND
Sbjct: 183 GGTYFLISRSLGPELGGSIGLIFAFANAVAVAMHTVGFAETVQVLMQETEVSMVDK-LND 241
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRI+G + + + I GM+WE+KAQ G +I P++ ++A+GF
Sbjct: 242 IRIIGVITVTCLLAISMAGMEWESKAQVLFFFVIMISFASYIIGTII-PATPQKQARGFF 300
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
N++P +R EG FF +F+++FP+ TG+ AGANI GDLK+P VAIP+GT
Sbjct: 301 SYRADIFATNFVPGWRGPEG---SFFGMFSIFFPSATGILAGANISGDLKDPNVAIPRGT 357
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNV----ANLTTAAL----------ESCKPH-- 230
+LA+ + SY + G +RDASG+V ++LT L C +
Sbjct: 358 MLAIFWTTVSYLIISATIGSCVVRDASGDVNDTISSLTGECLGVGCNYGWNFTDCMTNNT 417
Query: 231 CGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFF 290
C YGL N Y M ++SA P I AG + P++ Q L D++YPG+ FF
Sbjct: 418 CTYGLSNYYQSMSMVSAVAPLITAGIFGATLSSALACLVSAPKVFQCLCKDKLYPGIGFF 477
Query: 291 SKPYGRHGEPYRGY 304
K YG++ EP R Y
Sbjct: 478 GKGYGKNNEPLRSY 491
Score = 125 bits (302), Expect = 4e-27
Identities = 59/166 (35%), Positives = 98/166 (59%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
+V+WGSS + Y +S L+ H ++Y PQ LVL+G P RP+L+D TK
Sbjct: 591 EVNWGSSMQASSYNMALSQCVGLNQVEDHIKNYRPQCLVLSGPPCARPSLVDFIGAFTKN 650
Query: 378 GSFMIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
S MI A++ + + G S +++ RK+++FY + DL+ G L+Q++GL
Sbjct: 651 QSLMICANVLASGPSPGTADSMSSTHLKWLNNRKIKSFYHTVVADDLRTGVQMLLQSTGL 710
Query: 438 GKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRV 483
G++ PN+L++G+KK+W + I +Y G++ DAFDL+ V +LR+
Sbjct: 711 GRMKPNVLVMGYKKNWRKVQPGIIENYVGILHDAFDLQYGVCVLRM 756
Score = 99.5 bits (237), Expect = 3e-19
Identities = 58/190 (30%), Positives = 107/190 (56%), Gaps = 17/190 (8%)
Query: 592 KQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKF 651
K+ +D +WL +DGGL +L+PY++ R+ + +R+F + E + E + K ++ L+ +F
Sbjct: 819 KKTIDVYWLSDDGGLTLLIPYLLTRKKRWGRCKVRVF-VGGEAQQIEEQKKELKGLISRF 877
Query: 652 RIEYTELTLVRGIGDAPPESSWKMFNNIINDFK----------SEEKT---DILTSEAEL 698
R+ + ++ ++ I AP + F + I ++ ++E T + S+ E+
Sbjct: 878 RLGFKDIQVLPDINGAPQSEHIRKFEDFIAPYRVSSVQKDGQEADEATKEFSWMVSDEEM 937
Query: 699 KSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLPRKVS--ASLYMAWLEVLSRDL-PPVL 755
++ +K+ +S AA++++T+P+ R+ S + LYMAWLE++SRDL PPVL
Sbjct: 938 ETFKAKSLRQIRLNEVIQDYSRDAALIVVTMPVGRRGSCPSPLYMAWLEIVSRDLRPPVL 997
Query: 756 FVRGNDSCVL 765
VRGN VL
Sbjct: 998 LVRGNQENVL 1007
>UniRef50_UPI0000E46F80 Cluster: PREDICTED: similar to
bumetanide-sensitive Na-K-Cl cotransporter; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
bumetanide-sensitive Na-K-Cl cotransporter -
Strongylocentrotus purpuratus
Length = 961
Score = 222 bits (543), Expect = 2e-56
Identities = 141/471 (29%), Positives = 235/471 (49%), Gaps = 27/471 (5%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
+V+WG S + Y+ + +L + H +++ PQ+L+L G P RPA++ + +TK
Sbjct: 491 EVNWGDSNQAFLYKRAIQTTIKLGNVPEHVKTFRPQILLLTGPPNCRPAMLHLCSHITKN 550
Query: 378 GSFMIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
S ++ ++ + R R EQ++ Y+KL+AF L++GA LMQ GL
Sbjct: 551 TSLLLCGNVIIGEQPEVFRQLRTTEYEQWLNYKKLKAFLAFTTAPTLRKGAQQLMQLGGL 610
Query: 438 GKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRVPGTSQTVQRWRWTP 497
GK+ PN + +GFK++W+ + + + DY G+I DAFDL+L V ILR+ S +
Sbjct: 611 GKIRPNTMFMGFKRNWSACKPEDLLDYVGIIHDAFDLQLGVCILRLQEGSDVSAALDFEK 670
Query: 498 RVVSEPNNFELVMHTQVLALMNXXXXXXXXXXXXXXXXXXXXXXXNQLSNETSSSEQNPE 557
EP N + + + N ++ E E+ E
Sbjct: 671 E---EPYNQKEDLQPENEKACNSITTPTITITGTTQKDNAMKDNIDEEDEEEEEEEKEKE 727
Query: 558 S-------IGGEALRSANFSR---TSRRKLSN---GALSFRALSFNCKQ---YVDAWWLY 601
+ + ++ N SR TS + + N G++ F KQ +D WWL+
Sbjct: 728 NAKESTALVHNSDNQTNNQSRPLLTSEKLVRNMPIGSVIKTTQKFQGKQPKGTIDVWWLF 787
Query: 602 EDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIEYTELTLV 661
+DGGL +L+P+++ ++ K LR+FA K++ + + E + M +LL KFRI + + ++
Sbjct: 788 DDGGLTLLIPHLLTQKTNWQKCKLRVFASGKKE-RVDDEKRKMANLLSKFRIPHDSVNII 846
Query: 662 RGIGDAPPESSWKMFNNIINDFKSEEKTDILT-----SEAELKSQYSKTSXXXXXXXXXX 716
IG P +S + FN II + +E D SE +++S KT
Sbjct: 847 PNIGKLPSAASIEKFNKIIEPWLLKEGEDPKAYPWKISEQDVESLNDKTMRQIRLRELLQ 906
Query: 717 QHSTKAAIVIITLPLPRK--VSASLYMAWLEVLSRDLPPVLFVRGNDSCVL 765
+HS A++++++LP+PRK +YM WLEVLS DLPP+L +RGN + VL
Sbjct: 907 EHSKDASLIVMSLPMPRKSLCPPIMYMCWLEVLSGDLPPMLLMRGNQTSVL 957
Score = 216 bits (527), Expect = 2e-54
Identities = 115/303 (37%), Positives = 171/303 (56%), Gaps = 12/303 (3%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YY++SRSLG EFG S+G++F+ AN +A +M +GF +++ LLK + ++VD VND
Sbjct: 96 GGAYYMISRSLGPEFGGSIGLIFSVANTIAVAMYVVGFSETVALLLKDYDAQMVDL-VND 154
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
+RI+G + ++V+ I IGM WE K Q L G+ + P ++ + AKGF
Sbjct: 155 VRIIGMITIVVLLAIIFIGMAWEAKIQLVLLVVLSIAILNMVVGSFL-PVTEAKAAKGFT 213
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G +N P F+ E FFSVF+++FPA TG+ AGANI GDL + AIPKGT
Sbjct: 214 GYRKDVFVQNLKPGFQDGE----TFFSVFSIFFPAATGILAGANISGDLHDAQKAIPKGT 269
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNV-----ANLTTAALESCKPHCGYGLHNNYAI 241
L A+ IS Y + L G +R+A+G++ N+TTA L C YGL N+ A+
Sbjct: 270 LWAILISTVIYVGLSWLIGGCMIREATGSIVDVIAGNVTTACLNGTL-ECEYGLVNDLAV 328
Query: 242 MQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPY 301
+++S W P + AG + P++ QA+ D+I+P + +F+ G EP
Sbjct: 329 TKVISGWVPLVLAGIFAASLSSALASLVSAPKVFQAVCKDKIFPKIEYFAHGVGAGDEPK 388
Query: 302 RGY 304
R Y
Sbjct: 389 RAY 391
>UniRef50_Q4SHN3 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 5 SCAF14581, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 954
Score = 217 bits (531), Expect = 7e-55
Identities = 135/340 (39%), Positives = 184/340 (54%), Gaps = 44/340 (12%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG S+G++FAFANAVA +M +GF +++ LLK H +VD +ND
Sbjct: 185 GGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVDLLKEHSAIMVD-PLND 243
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRIVG + ++++ I GM+WE KAQ L G +I P+++ ++AKG
Sbjct: 244 IRIVGCITVVLLLGISVAGMEWEAKAQLVLLVILLVAIANVFVGTVI-PATEEQKAKGIF 302
Query: 127 GIN-------LQTIREN------------------WLPNFRYSEGREHDFFSVFAVYFPA 161
N L + R +L NF FFSVF+++FPA
Sbjct: 303 KYNCERGPRVLNSKRSKMKNTLMLSVLSFFFKAKIFLENFTPDFRNGETFFSVFSIFFPA 362
Query: 162 VTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLTT 221
TG+ AGANI GDLK+P AIPKGTLLA+ I+ +Y + I A+RDA+GN+ +L T
Sbjct: 363 ATGILAGANISGDLKDPQGAIPKGTLLAILITGLTYLGVAICVSACAVRDATGNITDLIT 422
Query: 222 ----------AALE------SCKPH-CGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXX 264
AA E SC C +GL+NN +M +S +GP I AG +
Sbjct: 423 PGVPCTGPAMAACELGYNFSSCAVEPCPFGLNNNNQMMTFVSGFGPLIIAGTFSATLSSA 482
Query: 265 XXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYRGY 304
P++ QAL D IY L FF+K YG++ EP RGY
Sbjct: 483 LASLVSAPKVFQALCKDNIYKALHFFAKGYGKNDEPIRGY 522
Score = 111 bits (266), Expect = 9e-23
Identities = 57/168 (33%), Positives = 95/168 (56%), Gaps = 2/168 (1%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
DV+WGSS + + VS LS H +++ PQ+L + G+ RPAL+D+A+ TK
Sbjct: 622 DVNWGSSKQAVTFVSAVSNALSLSGVEDHVKNFRPQILAMTGSVRDRPALLDLANCFTKN 681
Query: 378 GSFMIVADITDTALTKG-ERVSRQHIGEQ-FVKYRKLRAFYVLLQGLDLKRGANALMQAS 435
+ +I ++ E ++ Q +++ K +AFY + D + GA +L+Q S
Sbjct: 682 FGLCLSCEIFVGPRSEALEEINASMEKNQLWLRKTKRKAFYTPVVCKDFRAGAESLLQVS 741
Query: 436 GLGKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRV 483
GLG++ PN LL+GFK +W N+ + + Y G++ DAFD + + ILR+
Sbjct: 742 GLGRMKPNTLLMGFKSNWRNSGTEMVQCYVGILHDAFDFEYGILILRM 789
Score = 66.1 bits (154), Expect = 3e-09
Identities = 33/80 (41%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Query: 592 KQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKF 651
K +D WW+++DGGL +LLPYI+ R LRIF I + + E + + M SLL+KF
Sbjct: 875 KGTIDVWWMFDDGGLTLLLPYILTTRKKWKDCTLRIF-IAGQPERSELDKEEMRSLLQKF 933
Query: 652 RIEYTELTLVRGIGDAPPES 671
RI T++ ++ I PP S
Sbjct: 934 RINCTDIIVIDDI-HMPPSS 952
>UniRef50_Q8JHB5 Cluster: Renal Na-K-Cl cotransporter isoform AFno8;
n=14; Gnathostomata|Rep: Renal Na-K-Cl cotransporter
isoform AFno8 - Squalus acanthias (Spiny dogfish)
Length = 1091
Score = 208 bits (508), Expect = 4e-52
Identities = 123/298 (41%), Positives = 169/298 (56%), Gaps = 27/298 (9%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG S+G++F+FANAVA +M +GF +++ +LK + +VD ++D
Sbjct: 269 GGAYYLISRSLGPEFGGSIGLIFSFANAVAVAMYVVGFAETVVDILKENNALMVD-PISD 327
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRIVG + + + I GM+WETKAQ L G +I PS+ ++ KGF
Sbjct: 328 IRIVGCITTVALLGITVAGMEWETKAQVILLMILLIGIANFFIGTVI-PSTTEKKGKGFF 386
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
+ EN+ P+FR EG FFSVFA++FPA TG+ AGANI GDLK+P VAIPKGT
Sbjct: 387 NYHANVFAENFGPSFRDGEG----FFSVFAIFFPAATGILAGANISGDLKDPQVAIPKGT 442
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMS 246
+LA+ I+ +Y + I G +RDA+G+V N T ++ SC N A L
Sbjct: 443 MLAIFITTLTYIVVAICIGATVVRDATGSV-NDTISSSTSC---------NGSAACML-- 490
Query: 247 AWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYRGY 304
+ ++ C + QAL D IY GL FF K YG++ EP R Y
Sbjct: 491 ---GYDFSAC------NTHPCNFGLMNNFQALCKDNIYKGLYFFGKGYGKNSEPIRSY 539
Score = 120 bits (288), Expect = 2e-25
Identities = 71/189 (37%), Positives = 104/189 (55%), Gaps = 16/189 (8%)
Query: 592 KQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKF 651
K +D WWL++DGGL IL+PY++ R LRIF K E E + M +LL KF
Sbjct: 900 KGTIDVWWLFDDGGLTILIPYLLTTRKKWCGCKLRIFIGGKLDSIDE-EKRAMAALLGKF 958
Query: 652 RIEYTELTLVRGIGDAPPESSWKMFNNIINDFKSEEKT------DILTSE-------AEL 698
RI+ ++ ++ I P + SWK F +I ++ E + ++L E AEL
Sbjct: 959 RIQCADIKVIGDINMKPSKESWKTFEELIEPYQLHESSKDPATAEVLQEEYPWKITDAEL 1018
Query: 699 KSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLPRK--VSASLYMAWLEVLSRDLPPVLF 756
+ KT ++S A I++++LP+ RK VS+ LYMAWLE+LSR+LPPV+
Sbjct: 1019 ERFKDKTYRQVRLNELLQENSRAANIIVVSLPIARKEAVSSYLYMAWLEILSRNLPPVIM 1078
Query: 757 VRGNDSCVL 765
+RGN VL
Sbjct: 1079 IRGNQKNVL 1087
Score = 114 bits (274), Expect = 1e-23
Identities = 56/170 (32%), Positives = 96/170 (56%), Gaps = 6/170 (3%)
Query: 318 DVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKI 377
+V+WGSS + Y + L+ H +++ PQ +VL G+P+ RPAL+D+ TK
Sbjct: 639 EVNWGSSAQAMSYVTALQDALSLTGVNDHIKNFRPQCIVLTGSPVSRPALLDLTLSFTKN 698
Query: 378 GSFMIVADITDTALTKGERVSRQHIG----EQFVKYRKLRAFYVLLQGLDLKRGANALMQ 433
S I + + + + VS ++ +Q++ K +AFY + +L+ G L+Q
Sbjct: 699 FSLCICSQVFMGP--RKQTVSEMNVNMDKYQQWLAKNKKKAFYAAVAEDNLRDGVKCLLQ 756
Query: 434 ASGLGKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRV 483
ASGLG++ PN L+IG+K+DW + + +Y G++ DAFD + + ILR+
Sbjct: 757 ASGLGRMKPNTLVIGYKRDWRTTHSQDVENYVGILHDAFDFEYGLIILRI 806
>UniRef50_UPI000155D209 Cluster: PREDICTED: similar to NaCl
electroneutral Thiazide-sensitive cotransporter; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to NaCl
electroneutral Thiazide-sensitive cotransporter -
Ornithorhynchus anatinus
Length = 773
Score = 201 bits (491), Expect = 5e-50
Identities = 102/229 (44%), Positives = 142/229 (62%), Gaps = 6/229 (2%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG Y+L+SRSLG E G S+G++FAFANAVA +M+T+GF +++ LL+ +G IVD ND
Sbjct: 312 GGTYFLISRSLGPELGGSIGLIFAFANAVAVAMHTVGFAETVRDLLQEYGSPIVD-PTND 370
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRI+G V + V+ I GM+WE+KAQ G LI PS + + AKGF
Sbjct: 371 IRIIGVVTVTVLLAISLAGMEWESKAQVLFFLVIMVSFANYFVGTLIPPSEE-KAAKGFF 429
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
+N++PN+R +EG FF +F+++FP+ TG+ AGANI GDLK+PAVAIPKGT
Sbjct: 430 SYRADIFAQNFVPNWRGAEG---SFFGMFSIFFPSATGILAGANISGDLKDPAVAIPKGT 486
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKP-HCGYG 234
L+A+ + SY + G +RDASG + + C+ CGYG
Sbjct: 487 LMAIFWTTVSYLAISATIGSCVVRDASGGLNDTVPPGSPDCEGLACGYG 535
Score = 105 bits (251), Expect = 6e-21
Identities = 66/190 (34%), Positives = 104/190 (54%), Gaps = 17/190 (8%)
Query: 592 KQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKF 651
K+ +D +WL++DGGL +L+PY++ R+ K +R+F + + ++ + E K + SLL KF
Sbjct: 580 KKTIDIYWLFDDGGLTLLIPYLLGRKKRWSKCKIRVF-VGGQINRMDEERKAIISLLSKF 638
Query: 652 RIEYTELTLVRGIGDAPPESSWKMFNNII-----ND-FKSEEKTDIL-------TSEAEL 698
R+ + E+ ++ I P K F ++I ND FK E + + S+ E+
Sbjct: 639 RLGFHEVHVLPDINQMPRPEHTKRFEDLIAPFRLNDGFKDEATVNEMRHDCPWKISDEEI 698
Query: 699 KSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLPR--KVSASLYMAWLEVLSRDL-PPVL 755
K+ +S AA+++ITLP+ R K +SLYMAWLE LS+DL PPV+
Sbjct: 699 TKHKIKSLRQVRLNEILLDYSRDAALIVITLPVGRKGKCPSSLYMAWLETLSQDLRPPVI 758
Query: 756 FVRGNDSCVL 765
RGN VL
Sbjct: 759 LTRGNQENVL 768
>UniRef50_P34261 Cluster: Uncharacterized amino-acid permease
B0303.11; n=2; Caenorhabditis|Rep: Uncharacterized
amino-acid permease B0303.11 - Caenorhabditis elegans
Length = 903
Score = 154 bits (373), Expect = 1e-35
Identities = 114/452 (25%), Positives = 201/452 (44%), Gaps = 21/452 (4%)
Query: 322 GSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSFM 381
G Y + + EL R ++PQ+L+L+G+P RP L+D AH +T+ S +
Sbjct: 448 GEECPKSMYSSVLEQMHELQQEPDSRRHFHPQILLLSGSPAARPGLVDFAHSITRGKSLL 507
Query: 382 IVADITDTALTKGERVSRQHIGEQ---FVKYRKLRAFYVLLQGLDLKRGANALMQASGLG 438
I I + + + I +Q +++ R++ AF + GAN L+Q LG
Sbjct: 508 ICGYIIPQSPCSRSYLLQLKIDKQINDWLRAREVNAFGAAICCTKQAEGANILLQ---LG 564
Query: 439 KLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRVPGTSQTVQRWRWTPR 498
+L PNIL++G+K W + IS+YYG++ +AFD ++ V I R + V + R
Sbjct: 565 RLRPNILMLGYKTGWEKLSKESISEYYGMLSNAFDKQVGVIIFRNEASGFDVTS---SIR 621
Query: 499 VVSEP-NNFELVMHTQVLALMNXXXXXXXXXXXXXXXXXXXXXXXNQLSNETSSSEQNPE 557
P N+ E + A + E+
Sbjct: 622 KNGAPINDDEDLAEYVDSATPKLADQGSQKKDVPRGKLLNTFRKMSMADLESGGRRSTSS 681
Query: 558 SIGGEALRSANFSRTSRRKLSNGALSFRALSFNCKQYVDAWWLYEDGGLNILLPYIIARR 617
S + + + S ++ + FR N + +D +WL E GGL +L PY++ +
Sbjct: 682 STRFQVIDKHSISEPDQKIIMAQMFRFRKRIPNAR--IDVFWLREAGGLTMLAPYLLTQA 739
Query: 618 G-YKHKLPLRIFAIT--KEQHKREFENKCMESLLKKFRIEYTELTLVRGIGDAPPESSWK 674
G + +R+F T K+ + E K M ++L+KF I+ ++L ++ P + ++
Sbjct: 740 GSFLEGAHIRVFTKTDGKDNKRINEEQKNMAAILRKFHIDSSDLHILPEFSKPPCKQTYD 799
Query: 675 MFNNIINDFKSE-----EKTDILTSEAELKSQYSKTSXXXXXXXXXXQHSTKAAIVIITL 729
F I+ +K E E D ++ + KT +HS+ A +++ TL
Sbjct: 800 EFRAKIDKYKVETSSSGEPVDGSFDNNQIFNLREKTRSFLRASELIREHSSDADLIVCTL 859
Query: 730 PLPR-KVSASLYMAWLEVLSRDLPPVLFVRGN 760
P R ++ + +Y+ W+++LSR PP VRGN
Sbjct: 860 PSARPEIPSPIYLGWIDMLSRQTPPTCLVRGN 891
Score = 47.6 bits (108), Expect = 0.001
Identities = 48/201 (23%), Positives = 84/201 (41%), Gaps = 17/201 (8%)
Query: 3 ASERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDN 62
+SE G V +++ S EF S I++ F VA S +++ H+ T L+++D
Sbjct: 79 SSEVGFVKTMLAYS-STEFAISFSIIYLFCLLVATSTFLTSAAEAVLHIFSTFSLELLDG 137
Query: 63 DVNDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERA 122
+D+R+V +V L+ +C + + F+ A+ S V
Sbjct: 138 ATHDLRLVSSVLSLITLALCMVRNRNARFVRTFIFALTCI--------AIALQLSSVMFR 189
Query: 123 KGFVGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAI 182
G + + R +P+ + ++FA FPA NI L+N A
Sbjct: 190 YGEYQLRRVSDRNAMIPS-----PPNEEISTIFAQLFPAAMCGLTILNIGSKLQNTA--- 241
Query: 183 PKGTLLALAISVTSYFTMVIL 203
P+G L+A+A+S Y +L
Sbjct: 242 PRGALIAIAVSACFYGAAAML 262
>UniRef50_Q8IUN5 Cluster: SLC12A1 protein; n=27; Euteleostomi|Rep:
SLC12A1 protein - Homo sapiens (Human)
Length = 430
Score = 153 bits (371), Expect = 2e-35
Identities = 81/183 (44%), Positives = 112/183 (61%), Gaps = 10/183 (5%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG S+G++FAFANAVA +M +GF +++ LLK +VD ND
Sbjct: 242 GGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVDLLKESDSMMVD-PTND 300
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRI+G++ ++++ I GM+WE KAQ L G +I PS++ ++++GF
Sbjct: 301 IRIIGSITVVILLGISVAGMEWEAKAQVILLVILLIAIANFFIGTVI-PSNNEKKSRGFF 359
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDL----KNPAVAI 182
EN+ P F EG FFSVFA++FPA TG+ AGANI GDL K A +
Sbjct: 360 NYQASIFAENFGPRFTKGEG----FFSVFAIFFPAATGILAGANISGDLEALRKQGASPL 415
Query: 183 PKG 185
P+G
Sbjct: 416 PQG 418
>UniRef50_UPI000051AA81 Cluster: PREDICTED: similar to sodium
chloride cotransporter 69 CG4357-PA, isoform A, partial;
n=1; Apis mellifera|Rep: PREDICTED: similar to sodium
chloride cotransporter 69 CG4357-PA, isoform A, partial
- Apis mellifera
Length = 289
Score = 130 bits (313), Expect = 2e-28
Identities = 57/138 (41%), Positives = 96/138 (69%)
Query: 346 HSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSFMIVADITDTALTKGERVSRQHIGEQ 405
H ++Y PQ+L L+G P RPAL+ +A+++TK S +I +I T L+ R R G
Sbjct: 7 HVKNYAPQILALSGAPGARPALLHLANLITKNHSLLICGEICPTRLSYRLRSMRLRNGYA 66
Query: 406 FVKYRKLRAFYVLLQGLDLKRGANALMQASGLGKLSPNILLIGFKKDWTNAEHKQISDYY 465
++ +++++FY +++ L +RGA+ALMQA+G+GKL+PN++L+G+K W+ HK + +Y+
Sbjct: 67 WLHQQRIKSFYHVVEDLSFERGASALMQATGVGKLAPNVVLMGYKTHWSTCNHKDLQEYF 126
Query: 466 GVIQDAFDLKLAVTILRV 483
V+ +AFD KLAV +LR+
Sbjct: 127 NVLHNAFDQKLAVAMLRI 144
Score = 46.4 bits (105), Expect = 0.003
Identities = 17/23 (73%), Positives = 20/23 (86%)
Query: 595 VDAWWLYEDGGLNILLPYIIARR 617
+D WWLY+DGGL ILLPYII+ R
Sbjct: 262 IDVWWLYDDGGLTILLPYIISTR 284
>UniRef50_A0LPD8 Cluster: Amino acid permease-associated region;
n=2; Bacteria|Rep: Amino acid permease-associated region
- Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 733
Score = 128 bits (308), Expect = 7e-28
Identities = 98/296 (33%), Positives = 137/296 (46%), Gaps = 47/296 (15%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG V I F A AVA ++ +GF ++L G
Sbjct: 80 GGAYYLISRSLGVEFGGVVAIFFYIAQAVAVTLYVVGFTEALLSAFPDMGASF------- 132
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
R V + +V+ V IG W + Q F+ GA G S ++ RA
Sbjct: 133 -RTVATLTNIVVFVCVYIGAAWTIRIQYFILAMLLLSFFSFFLGAGTGFSPEILRA---- 187
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
NL +W P EH+FFSVFA++FPAVTG+ AG N+ GDLK+P +IP+GT
Sbjct: 188 --NLSA---HWSP--------EHEFFSVFALFFPAVTGIMAGVNMSGDLKDPGRSIPRGT 234
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMS 246
A+ +S Y + + +G+V T A L G+G +M+ +
Sbjct: 235 FAAIGVSTIVYAAIAFM--------FAGSV---TRADL------LGHGF-----VMKDRA 272
Query: 247 AWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYR 302
+ IYAG PR++QA D I+ L +F++ GR GEP R
Sbjct: 273 FFPSLIYAGVICATLSSALGSMMGAPRILQAFARDNIFRRLRWFARGSGRSGEPRR 328
Score = 61.7 bits (143), Expect = 7e-08
Identities = 39/143 (27%), Positives = 62/143 (43%), Gaps = 2/143 (1%)
Query: 317 IDVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTK 376
I V WG G YQ + L H +++ P +L L+G R L + A T
Sbjct: 429 IRVKWGDLDSGLAYQFARKALLRLERERYHPKNWRPSILALSGGAHNRLHLAEYACWFTA 488
Query: 377 IGSFMIVADITDTALTK--GERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQA 434
+ + + L + R + I +F+ L AF V++ D+ AL+Q
Sbjct: 489 DSGIVFIGQVIRGELEELLDRRREAEAILRRFILKEALPAFPVVIVEEDIHAAIKALLQC 548
Query: 435 SGLGKLSPNILLIGFKKDWTNAE 457
G+G + PNI+L+G +D AE
Sbjct: 549 QGIGGMRPNIVLLGMSRDPEKAE 571
>UniRef50_Q9C258 Cluster: Related to na+/k+/2cl-cotransporter; n=3;
cellular organisms|Rep: Related to
na+/k+/2cl-cotransporter - Neurospora crassa
Length = 1247
Score = 128 bits (308), Expect = 7e-28
Identities = 94/296 (31%), Positives = 141/296 (47%), Gaps = 28/296 (9%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG S+GILF A + ++N +G D L L + ++
Sbjct: 77 GGAYYLISRSLGPEFGGSIGILFYLAQVLNTALNVVGLIDCLRLNLGS----VMAQGYWW 132
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPS-SDVERAKGF 125
+ ALLV ++C G KA N L A+ PS +D F
Sbjct: 133 TYLFETGALLVCTLLCLAGSAMFAKASNALLAIMVISILSIPVSAIFLPSFNDPVSGIEF 192
Query: 126 VGINLQTIRENWLPNFRYSEGREHDFF-SVFAVYFPAVTGVQAGANICGDLKNPAVAIPK 184
G++L T+R N P+F E + F +F + FPA +G+ AGA++ GDL+NP+ IP+
Sbjct: 193 TGVSLTTLRSNLWPHFAGDEFKGAGTFRDLFGILFPATSGIFAGASMSGDLRNPSKDIPR 252
Query: 185 GTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQL 244
GTL A+ ++ SY ++I ++A+ TT H G L N ++Q
Sbjct: 253 GTLWAMLSTLISYVVVII------------SLASSTT--------H-GTFLRNT-NVIQE 290
Query: 245 MSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEP 300
+ W P I+AG + +L+QAL D++ PG+ F K + EP
Sbjct: 291 TNVWPPIIFAGEFATCFFSALMGVIGSAKLMQALARDKLVPGISIFGKGTKKTDEP 346
Score = 50.4 bits (115), Expect = 2e-04
Identities = 31/132 (23%), Positives = 64/132 (48%), Gaps = 5/132 (3%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
WG ++ Y ++ L + H + + PQ+++L P ++ LI + + K G +
Sbjct: 452 WGDVSQNLIYHQVRKYLLRL--KPEHIKFWRPQIILLINNPRKQTRLIQFCNSMKKGGLY 509
Query: 381 MIVADITDTALTKG--ERVSRQHIGEQFV-KYRKLRAFYVLLQGLDLKRGANALMQASGL 437
++ I + G E +Q +++ ++ +++AF L + G L+ ++GL
Sbjct: 510 ILGHVIVTDDFSAGVTEAKLQQAAWSKYISEFSRIKAFVQLTMSPTITWGVRNLILSAGL 569
Query: 438 GKLSPNILLIGF 449
G + PNI +IGF
Sbjct: 570 GGMRPNIAVIGF 581
>UniRef50_A2FMM0 Cluster: Amino acid permease family protein; n=2;
Trichomonas vaginalis G3|Rep: Amino acid permease family
protein - Trichomonas vaginalis G3
Length = 828
Score = 116 bits (280), Expect = 2e-24
Identities = 87/299 (29%), Positives = 135/299 (45%), Gaps = 39/299 (13%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GGVY+ +SRSLG +FG ++G++F+ A +NT GF + + ++ G I + D
Sbjct: 136 GGVYFCISRSLGPDFGGTIGVVFSIATIFTGVLNTFGFVEVVKDII---GKDITKDGKWD 192
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
I I+G + + ++ I + +E Q L G I P + K V
Sbjct: 193 IPIIGISLVTFLVILICISLVFEAYLQYILAVVIALSIITILIGFAI-PG----KPKWIV 247
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
++ N P F+ EG + F+++FAV+FPA TG+ AGANI GDLK P +IP GT
Sbjct: 248 ----TNLKNNLYPKFQ--EG--NTFWTIFAVFFPACTGIMAGANISGDLKEPQKSIPIGT 299
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMS 246
L A+ + Y + A R+ L ++++++ +
Sbjct: 300 LGAIGFTTLLYLVTATIVASAADRET----------------------LWSDFSLLSRIC 337
Query: 247 AWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLI-FFSKPYGRHGEPYRGY 304
AW FIY G P+L QAL D I P FF+K + +P RG+
Sbjct: 338 AWKWFIYIGVLAASFSSTSSAMVGGPKLFQALCRDDILPKFFKFFAKGKAKTDDPIRGF 396
Score = 69.3 bits (162), Expect = 4e-10
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 595 VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIE 654
+D WWL +DGGL +LL Y+I ++ K LR+ + LL+ FRI+
Sbjct: 667 IDVWWLSDDGGLVLLLGYLIQKKKSWEKCQLRVLTAAPRNDGLSDVQVRVSKLLQLFRID 726
Query: 655 YTELTLVRGIGDAPPESSWKMFNNIINDFKSEEKTDILTSEAELKSQYSKTSXXXXXXXX 714
E+ ++ GI D P + + M+N + E+ D ++Q K
Sbjct: 727 -AEVIVIPGIDDKPGDDTINMWNE-----RGIEEGD--------ENQKRKVQTFLRLREL 772
Query: 715 XXQHSTKAAIVIITLPLPRKV-SASLYMAWLEVLSRDLPPVLFVRGNDSCVL 765
+S +++V+ ++P+PR A +++ ++++S +PP ++V GN V+
Sbjct: 773 ILDNSAHSSMVLCSMPIPRATQDAKVWLGTIDIVSDSMPPFIWVHGNGENVV 824
>UniRef50_Q5B4Q2 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 1174
Score = 116 bits (279), Expect = 2e-24
Identities = 93/323 (28%), Positives = 140/323 (43%), Gaps = 31/323 (9%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHG---LKIVDND 63
GG YYL+SRSLG EFG S+GI+F + + MN +G D +
Sbjct: 147 GGAYYLISRSLGPEFGGSIGIVFYLGSVLNTGMNAVGLIDCFKQNFGAETGTWYNFLREG 206
Query: 64 VNDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGAL-IGPSSDVERA 122
+ G + LLV IC G +A N L A+ + P +
Sbjct: 207 FWWQYLWGTIILLVCTGICLAGSALFARASNGLLVILLIATLSIPLSAVFMEPFRAPKLG 266
Query: 123 KGFVGINLQTIRENWLPNF-RYSEGRE----HDFFSVFAVYFPAVTGVQAGANICGDLKN 177
F GI+L+T+ EN P + ++G + F +F + FPA G+ AGA++ GDLKN
Sbjct: 267 VHFTGISLRTLMENLKPRLTKGADGSQLSTRETFQDLFGILFPATGGIFAGASMSGDLKN 326
Query: 178 PAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHN 237
P+ +IPKGTL LA++ Y T+VI + A+LT +L +N
Sbjct: 327 PSRSIPKGTLYGLALTFILY-TLVIFA----------MAASLTRDSL-----------YN 364
Query: 238 NYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRH 297
N I+Q+ + G + +G + +L+QA+ D + PGL FSK +
Sbjct: 365 NANIVQIANLSGAIVLSGEFATSFFSALMGLIGSAKLLQAIAKDSLLPGLNLFSKGTRKK 424
Query: 298 GEPYRGYXXXXXXXXXXXXIDVS 320
EP R D++
Sbjct: 425 DEPVRAIIVTFIAAQLTMLFDIN 447
Score = 38.3 bits (85), Expect = 0.77
Identities = 29/129 (22%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
WG ++ Y ++ L H + + PQ+L+ L+ + L K F
Sbjct: 533 WGDVSQSLIYHQVRKYLLRLKQE--HVKFWRPQILLFVNDLEHEFKLVAFCNSLKKGALF 590
Query: 381 MI--VADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGLG 438
++ V D + E +Q + V+ K++AF + ++ G ++ SGLG
Sbjct: 591 VLGHVIVTDDFSFAVPEARRQQTTWTKLVESLKVKAFVNIAVSPSVEWGVRNIVLNSGLG 650
Query: 439 KLSPNILLI 447
+ PNI++I
Sbjct: 651 GMRPNIVII 659
>UniRef50_UPI000023EFC2 Cluster: hypothetical protein FG05147.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG05147.1 - Gibberella zeae PH-1
Length = 1326
Score = 116 bits (278), Expect = 3e-24
Identities = 98/296 (33%), Positives = 141/296 (47%), Gaps = 31/296 (10%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG S+GILF A + ASMN +G D + L G +
Sbjct: 110 GGAYYLISRSLGPEFGGSIGILFYLAQVLNASMNVVGLIDCIRLNL---GPAFPEGYWTS 166
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALI-GPSSDVERAKGF 125
+ ALL+ +C +G ++A N L A+ P D + F
Sbjct: 167 Y-FLQTAALLLCTGLCFLGSATFSRASNALLAILSLAIISIPVSAIFKTPFRDEDLGIHF 225
Query: 126 VGINLQTIRENWLPNFR--YSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIP 183
G + T+ +N+LP+ + +G E F +F + FPA +G+ AGA++ GDLK+P+ +IP
Sbjct: 226 TGPSFDTLTDNFLPHLSSPHFKGLE-TFRDLFGILFPATSGIFAGASMSGDLKDPSRSIP 284
Query: 184 KGTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQ 243
GTL A+ + YF +VILS +A TT H + L N+ AI
Sbjct: 285 HGTLWAMLTTFIIYF-VVILS-----------LAASTT--------HDSF-LANDNAI-S 322
Query: 244 LMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGE 299
L++ P I AG +L QA D++ PGL FFSK +HG+
Sbjct: 323 LINLSQPVILAGECAVTFFSALMGLIGASKLFQAFSRDKLLPGLGFFSKG-TKHGD 377
Score = 52.4 bits (120), Expect = 4e-05
Identities = 35/133 (26%), Positives = 64/133 (48%), Gaps = 7/133 (5%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
WG ++ Y ++ L R H + + P +++L P ++ LI + L K GS
Sbjct: 485 WGDVSQNLIYHQVRKYLLRL--RPEHIKFWRPHIILLINNPRRQTRLIQFCNSLKK-GSL 541
Query: 381 MIVADITDTA-LTKGERVSR--QHIGEQFV-KYRKLRAFYVLLQGLDLKRGANALMQASG 436
I+ + T G +R QH +++ ++ K++AF L + G L+ ++G
Sbjct: 542 YILGHVIVTDDFNSGVHEARLQQHAWTKYISEFSKIKAFVQLTMSPTITWGIRNLILSAG 601
Query: 437 LGKLSPNILLIGF 449
LG + PNI ++GF
Sbjct: 602 LGGMRPNIAVLGF 614
Score = 35.1 bits (77), Expect = 7.1
Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 6/54 (11%)
Query: 717 QHSTKAAIVIITLPLPRK------VSASLYMAWLEVLSRDLPPVLFVRGNDSCV 764
QHS A+++ TLP+P + + Y++ +EVL +LPP L V N+ V
Sbjct: 1269 QHSKGTAVLLSTLPIPTEGTCLDDAATIQYLSDVEVLCNELPPTLLVLSNNMTV 1322
>UniRef50_A0AV02 Cluster: Solute carrier family 12 member 8; n=25;
Euteleostomi|Rep: Solute carrier family 12 member 8 -
Homo sapiens (Human)
Length = 714
Score = 115 bits (277), Expect = 4e-24
Identities = 71/206 (34%), Positives = 108/206 (52%), Gaps = 15/206 (7%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GGVY ++S LG + G ++G+L+ F VA +M GF +S++ LL GL ++
Sbjct: 104 GGVYSMISSVLGGQTGGTIGLLYVFGQCVAGAMYITGFAESISDLL---GL----GNIWA 156
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
+R + LL + I G+ W + Q L ++G + ++ GF+
Sbjct: 157 VRGISVAVLLALLGINLAGVKWIIRLQLLLLFLLAVSTLDF----VVGSFTHLDPEHGFI 212
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G + + ++ N LP+ YS G FF+VF V+FPA TGV AG N+ GDL+ PA +IP G+
Sbjct: 213 GYSPELLQNNTLPD--YSPGES--FFTVFGVFFPAATGVMAGFNMGGDLREPAASIPPGS 268
Query: 187 LLALAISVTSYFTMVILSGMGALRDA 212
L A+ IS Y V L G R+A
Sbjct: 269 LAAVGISWFLYIVFVFLLGAICTREA 294
>UniRef50_Q8VI23-3 Cluster: Isoform 3 of Q8VI23 ; n=4; Eutheria|Rep:
Isoform 3 of Q8VI23 - Mus musculus (Mouse)
Length = 625
Score = 114 bits (274), Expect = 1e-23
Identities = 70/206 (33%), Positives = 107/206 (51%), Gaps = 15/206 (7%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GGVY ++S LG + G +VG+L+ F VA +M GF +S++ LL GL D+
Sbjct: 72 GGVYSMISSVLGGQMGGTVGLLYVFGQCVAGAMYITGFAESISDLL---GL----GDIWA 124
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
+R + LL + I G+ W + Q L ++G + ++ GF+
Sbjct: 125 VRGISVAVLLALLGINLAGVKWIIRLQLLLLLLLAVSTLDF----VVGSFTHLDPEHGFI 180
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G + + ++ N LP YS G FF+VF V+FPA TGV AG N+ GDL++PA ++P G+
Sbjct: 181 GYSPELLQSNILPE--YSPGES--FFTVFGVFFPAATGVMAGFNMGGDLRDPADSVPLGS 236
Query: 187 LLALAISVTSYFTMVILSGMGALRDA 212
L A+ +S Y L G R+A
Sbjct: 237 LAAVGVSWFLYIIFAFLLGAVCTREA 262
>UniRef50_Q2S0B7 Cluster: Na-K-Cl cotransporter, putative; n=6;
Bacteria|Rep: Na-K-Cl cotransporter, putative -
Salinibacter ruber (strain DSM 13855)
Length = 754
Score = 113 bits (272), Expect = 2e-23
Identities = 91/298 (30%), Positives = 133/298 (44%), Gaps = 43/298 (14%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YY++SRSLG E G +VGI A ++ ++ T+GF +S+ + T V ++
Sbjct: 93 GGAYYMISRSLGIEIGGAVGIPLYIAQGLSVALYTVGFAESVINAFPTLSTLSVLG-LSG 151
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
I+IVG + +++ V+ + KAQ F+ G+ + SD+ R G V
Sbjct: 152 IQIVGLIITILVAVLALGSPNIAIKAQYFILAAIVVSLVSLVAGSPV-EQSDI-RMWGAV 209
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
N + F+ VFAV+FPAVTG+ AG N+ GDL+NP AIP GT
Sbjct: 210 DAN-----------------QAAGFWEVFAVFFPAVTGIMAGVNLSGDLENPNKAIPWGT 252
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMS 246
A+ + Y T+ +L G+ A N A L L IM+ M+
Sbjct: 253 FGAVGVGYLVYMTLPLLLGLWA------NSATLIEDTL----------------IMRRMA 290
Query: 247 AWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYP-GLIFFSKPYGRHGEPYRG 303
WG I G W PR++QAL +D + P L + K G P G
Sbjct: 291 WWGDAILLGVWGATLSSAIGSILGAPRVLQALALDGVLPQSLKWLGKGAGEENIPRGG 348
Score = 44.4 bits (100), Expect = 0.012
Identities = 33/140 (23%), Positives = 64/140 (45%), Gaps = 3/140 (2%)
Query: 320 SWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGS 379
+WG +G T + + L+ +++ P +LVL+G P +R +I++A LT +
Sbjct: 450 TWGDVRQGLWMSLTRAGLLHLNAD-PDPKNWRPHILVLSGAPRRRWPVIELASALTHNQA 508
Query: 380 FMIVADITDTALTKGERVSRQHIG--EQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
M V + + R+ +++ R +++ D G L++ GL
Sbjct: 509 LMTVGTVLRPSEASDFEAQREAEATLREYLGSRGVQSLVRTTTAEDPFAGGERLIEDYGL 568
Query: 438 GKLSPNILLIGFKKDWTNAE 457
G L PN +++G +D T+ E
Sbjct: 569 GVLKPNTIMLGHTEDPTHHE 588
>UniRef50_Q0UWR5 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1346
Score = 112 bits (269), Expect = 4e-23
Identities = 91/303 (30%), Positives = 135/303 (44%), Gaps = 31/303 (10%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSL--NHLLKTHGLKIVDNDV 64
GG YYL+SRSLG EFG ++GI+F + S+N +G D L N + +
Sbjct: 173 GGAYYLISRSLGPEFGGAIGIVFYLGTVFSTSLNAVGLVDCLMVNFGEREGAMGQWVPQS 232
Query: 65 NDIRIVGAVALLVMC-VICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIG-PSSDVERA 122
+ + A +L +C ++C G +A N L A I P DV+
Sbjct: 233 YWFQFLWATIVLAICTLVCLAGSGLFARASNGLLIALLVAIASIPLSAAIRKPFVDVKET 292
Query: 123 KGFVGINLQTIRENWLPNFRY----SEGREHDFFS-VFAVYFPAVTGVQAGANICGDLKN 177
F G +L T R N LP+F S + H+ F +F + FPA G+ AGA++ GDLK+
Sbjct: 293 IIFTGFSLDTFRNNLLPHFTKGAAGSAVKGHESFQDLFGILFPATGGILAGASMSGDLKH 352
Query: 178 PAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHN 237
P+ AIPKGTL L ++ Y TMVI + + +++ T +
Sbjct: 353 PSKAIPKGTLYGLGLTFLLY-TMVIFA-------LAASISRET--------------FYK 390
Query: 238 NYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRH 297
N ++QL + G I G +L+QAL D + PGL F + +
Sbjct: 391 NTNVIQLTNISGIIILLGELATSLFSVLMGVIGSAKLLQALARDHLIPGLSIFGQGTKKA 450
Query: 298 GEP 300
EP
Sbjct: 451 DEP 453
Score = 56.8 bits (131), Expect = 2e-06
Identities = 35/131 (26%), Positives = 66/131 (50%), Gaps = 4/131 (3%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
WG ++G Y ++ L R H + + PQ+L+L P ++ LI + L K G F
Sbjct: 550 WGDVSQGLIYHQVRKYLLRL--RQEHVKFWRPQILLLVNDPRRQYKLIQFCNSLKKGGLF 607
Query: 381 MI--VADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGLG 438
++ V + A E +Q +++ + +++AF + ++ GA L+ +GLG
Sbjct: 608 VLGHVIVTNNFAEAVPEARRQQQSWTKYIDFSRIKAFVNIAISPAVEWGARNLVLGAGLG 667
Query: 439 KLSPNILLIGF 449
+ PNI+++GF
Sbjct: 668 GMRPNIVVMGF 678
Score = 35.9 bits (79), Expect = 4.1
Identities = 24/54 (44%), Positives = 30/54 (55%), Gaps = 6/54 (11%)
Query: 717 QHSTKAAIVIITLPLPRK-----VSASL-YMAWLEVLSRDLPPVLFVRGNDSCV 764
QHS A+V TLP P + S S+ Y++ LEVL + LPPVL V N V
Sbjct: 1289 QHSEDTAVVFTTLPSPVEGTCDSESESVKYISDLEVLCQGLPPVLLVHSNSMTV 1342
>UniRef50_O46100 Cluster: CG12773-PA; n=6; Endopterygota|Rep:
CG12773-PA - Drosophila melanogaster (Fruit fly)
Length = 712
Score = 110 bits (265), Expect = 1e-22
Identities = 84/296 (28%), Positives = 128/296 (43%), Gaps = 37/296 (12%)
Query: 5 ERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDV 64
E GGVY+L++ +LG+ FG ++G+L+ F AV ++N +GF +S+ L+ G K
Sbjct: 155 ESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGLVGLEGSKWA---- 210
Query: 65 NDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKG 124
IR A+L++ I G+ W K Q L G+ +S G
Sbjct: 211 --IRGFATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGSFTSEASG-----G 263
Query: 125 FVGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPK 184
F G EN P +Y +G + +F VF V+FP VTGV +G N+ GDL+ P+ IP
Sbjct: 264 FNGWASGNFVENLWP--KYDDG--YSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPN 319
Query: 185 GTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQL 244
GTL A S Y V+ G R L+ +Y I
Sbjct: 320 GTLAAFGTSTFLYLVFVLFLGATCQRSF----------------------LYTDYMISVK 357
Query: 245 MSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEP 300
+SA + AG + PR++Q++ + + PG+ K G + P
Sbjct: 358 VSAVHFLLLAGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVP 413
>UniRef50_A4QUB1 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1655
Score = 110 bits (265), Expect = 1e-22
Identities = 71/210 (33%), Positives = 108/210 (51%), Gaps = 8/210 (3%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG S+GILF + + ++N +G L + L+ + + +
Sbjct: 77 GGAYYLISRSLGPEFGGSIGILFYLSQVLNTALNVVG----LINCLELYFADQIPHGFWG 132
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGAL-IGPSSDVERAKGF 125
I ++ ALL +C G KA N L AL + P S+ F
Sbjct: 133 IYMLETAALLGCTAMCLAGSGMFAKASNALLAILLVSTFSIPLSALFLRPFSNPSLGIEF 192
Query: 126 VGINLQTIRENWLPNFRYSEGRE--HDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIP 183
G+++ T++ N LP+ + F +F + FPA +G+ AGA++ GDL+NP+ AIP
Sbjct: 193 TGLSMATLKTNLLPDTGSDSQFQGLSTFRELFGILFPATSGIFAGASMSGDLRNPSKAIP 252
Query: 184 KGTLLALAISVTSYFTMVILSGMGALRDAS 213
KGTL A+ +S + +VILS A+ S
Sbjct: 253 KGTLWAM-LSTFVVYLLVILSMASAITQPS 281
Score = 52.8 bits (121), Expect = 3e-05
Identities = 35/133 (26%), Positives = 63/133 (47%), Gaps = 7/133 (5%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
WG ++ Y ++ L R H + + PQ+++L G P ++ L+ + + K GS
Sbjct: 453 WGDVSQNLIYHQVRKYLLRL--RPEHIKFWRPQIILLVGDPRRQTRLVQFCNSMKK-GSL 509
Query: 381 MIVADI--TDTALTKGERVSRQHIG--EQFVKYRKLRAFYVLLQGLDLKRGANALMQASG 436
I+ + TD T + Q + +Y +++AF L + G L+ ++G
Sbjct: 510 YILGHVIVTDDFETGVQEAKLQQSAWTKYISEYSRIKAFVQLNMSPTITWGIRNLILSAG 569
Query: 437 LGKLSPNILLIGF 449
LG + PNI +IGF
Sbjct: 570 LGGMRPNIAVIGF 582
>UniRef50_UPI0000DB7B57 Cluster: PREDICTED: similar to CG12773-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to
CG12773-PA - Apis mellifera
Length = 677
Score = 109 bits (262), Expect = 3e-22
Identities = 83/296 (28%), Positives = 129/296 (43%), Gaps = 37/296 (12%)
Query: 5 ERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDV 64
E GGVY+L+S LG+ FG S+G+L+ F AV ++N +GF +SL L+ GL+ +
Sbjct: 147 ESGGVYFLLSHVLGSRFGGSIGLLYCFGQAVGCALNVLGFGESLAGLV---GLESAWAE- 202
Query: 65 NDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKG 124
R A++++ +I G+ W K Q L ++G + + G
Sbjct: 203 ---RGFACAAVILLSIINIAGVKWVIKLQFILLLILLLAGVDF----MVGSFTHINVEAG 255
Query: 125 FVGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPK 184
F G ++ N N Y +G + +F+VF V+FP VTGV AG N+ GDLK+P+ IP
Sbjct: 256 FEGWLSGNLKNNTFTN--YQDG--YSWFTVFGVFFPTVTGVLAGINMSGDLKHPSTDIPN 311
Query: 185 GTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQL 244
GTL A+ Y I R A L N+ I
Sbjct: 312 GTLAAVGTGTFLYLCFSIFLAATCTRKA----------------------LLTNFMIAST 349
Query: 245 MSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEP 300
+SA + AG + PR++Q++ + PG+ + G + P
Sbjct: 350 VSAISVLLLAGLYVSSFSSCLGAMYGTPRVLQSIASQNVLPGISCLQRGKGPNKVP 405
>UniRef50_A2QI38 Cluster: Complex: coimmunoprecipitation suggest a
direct interaction of human CIP1 with NKCC; n=7;
Eurotiomycetidae|Rep: Complex: coimmunoprecipitation
suggest a direct interaction of human CIP1 with NKCC -
Aspergillus niger
Length = 1245
Score = 109 bits (262), Expect = 3e-22
Identities = 86/305 (28%), Positives = 132/305 (43%), Gaps = 35/305 (11%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG S+GI+F + MN +G D + N + +
Sbjct: 195 GGAYYLISRSLGPEFGGSIGIVFYLGYVLNTGMNAVGLVDCFTQNFGSES-GTWGNFLRE 253
Query: 67 ---IRIVGAVALLVMCV-ICAIGMDWETKAQNFLXXXXXXXXXXXXXGAL-IGPSSDVER 121
+ + +L+MC IC G ++A N L A+ + P S +
Sbjct: 254 GFWWQYLWGTVILIMCTAICLAGSSIFSRASNGLLIILLIATFSIPVSAVFMKPFSIPKV 313
Query: 122 AKGFVGINLQTIRENWLPNFRYS------EGREHDFFSVFAVYFPAVTGVQAGANICGDL 175
F G+ LQT+ EN P GRE+ F +F + FPA G+ AGA++ GDL
Sbjct: 314 GVEFTGLRLQTLLENLKPKLTKGAAGSQIRGREN-FQDLFGILFPATGGIFAGASMSGDL 372
Query: 176 KNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGL 235
KNP+ +IPKGTL L ++ +Y +++ R++
Sbjct: 373 KNPSRSIPKGTLCGLVLTFITYAIVILAMAASITRES----------------------F 410
Query: 236 HNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYG 295
+ N ++Q+ + G I G + +L+QA+ D + PGL FF K
Sbjct: 411 YKNANVVQVANLSGSVILMGEFATSFFSALMGVIGSAKLLQAVARDGLLPGLSFFGKGTR 470
Query: 296 RHGEP 300
+ EP
Sbjct: 471 KTDEP 475
Score = 46.8 bits (106), Expect = 0.002
Identities = 36/148 (24%), Positives = 70/148 (47%), Gaps = 9/148 (6%)
Query: 320 SWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGS 379
SWG ++ Y ++ L R H + + PQ+L+ ++ +I + L K G
Sbjct: 580 SWGDVSQSLIYHQVRKYLLRL--RQEHVKFWRPQILLFVNDLSEQSKMISFCNSLKKGGL 637
Query: 380 FMI----VADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQAS 435
F++ V D TA+ + R +Q +FV+ +++AF + + G + ++
Sbjct: 638 FVLGHVLVTDDFTTAVPEARR--QQTAWTKFVESSRVKAFVNITVSPTAEWGVRNVTLSA 695
Query: 436 GLGKLSPNILLIG-FKKDWTNAEHKQIS 462
GLG + PNI++I F++ + E +S
Sbjct: 696 GLGGMRPNIVVIDQFREGKSLVERPSLS 723
>UniRef50_Q4P5L1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1564
Score = 107 bits (257), Expect = 1e-21
Identities = 71/209 (33%), Positives = 107/209 (51%), Gaps = 10/209 (4%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLL-KTHGLK-IVDNDV 64
GG YYL+SRSLG EFG S+G++F A+ A+MN +GF ++L ++ G +
Sbjct: 352 GGAYYLISRSLGPEFGGSIGLIFFAGQALNAAMNVLGFVETLTDAFGQSRGPSGSLPEGP 411
Query: 65 NDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGAL-IGPSSDVERAK 123
G+V LLV ++C +G +A L + + P D +R
Sbjct: 412 WFSFFYGSVVLLVSAIVCLVGSKLFARATLALALILCVAILSIPISSFTVQPFIDDDRGA 471
Query: 124 GFVGINLQTIRENWLPNFR-----YSEG-REHDFFSVFAVYFPAVTGVQAGANICGDLKN 177
+ G + T+R N P F S G + ++ SVF V FPAVTG+ AGA++ GDL+
Sbjct: 472 YYTGWSWDTLRGNLFPRFTSGAAGSSTGTQSENWQSVFGVLFPAVTGILAGASMSGDLRK 531
Query: 178 PAVAIPKGTLLALAISVTSY-FTMVILSG 205
P+ +IPKGT +L + Y + VI +G
Sbjct: 532 PSKSIPKGTNYSLLFTFLVYLISFVIFAG 560
Score = 54.4 bits (125), Expect = 1e-05
Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 3/134 (2%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
WG T Y ++ L R H + + PQ+L+LA P LI + L K G+
Sbjct: 739 WGDVTRNITYHFVRKYLLRLDERKGHVKYWRPQILLLANNPRSEWNLIIFCNSLKK-GAL 797
Query: 381 MIVADITDTALTK--GERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGLG 438
++ + T E +Q + V +++F ++ D + GA L+ + GLG
Sbjct: 798 YVLGHVLKGEFTDCLAELRKQQVAWLKLVDLTGIKSFVDVVIAKDEREGARNLILSCGLG 857
Query: 439 KLSPNILLIGFKKD 452
+ PNI+++G+ D
Sbjct: 858 GMRPNIVVMGYPSD 871
>UniRef50_A7RQ45 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 669
Score = 107 bits (256), Expect = 1e-21
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 39/297 (13%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GGVY+L+S LG G ++ +L+AF AV+ S+ G +SL H +
Sbjct: 81 GGVYFLLSHVLGQRAGGAISLLYAFGQAVSVSLFCAGLGESLAQT--AHW-----DSAWA 133
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
+R++G + L + ++ G+ W K Q L +IG + + A GF
Sbjct: 134 VRVIGLLTALAILLVVLAGVKWVVKLQLLLLAILMLSVLDF----VIGTFAHTDIAAGFT 189
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G + + +N P F G + +FF+VF V+FP+ TGV +G N+ GDLK+P+ IP GT
Sbjct: 190 GYKTENMEKNAAPQF----GAKQNFFTVFGVFFPSATGVLSGINMSGDLKDPSSNIPAGT 245
Query: 187 LLALAISVTS--YFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQL 244
L AL Y +L G R+A L +Y I
Sbjct: 246 LAALGFRWVGLLYILFAVLLGAVCTREA----------------------LLTDYMIASK 283
Query: 245 MSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPY 301
+S G G + PR++Q + D + P + K G + EPY
Sbjct: 284 VSLVGVLFLFGLYVSSLSSCLGAQYGAPRVLQVISQDNVVPIIKPLGKERGANKEPY 340
>UniRef50_A2DXA4 Cluster: Amino acid permease family protein; n=2;
Trichomonas vaginalis G3|Rep: Amino acid permease family
protein - Trichomonas vaginalis G3
Length = 813
Score = 105 bits (253), Expect = 3e-21
Identities = 84/299 (28%), Positives = 134/299 (44%), Gaps = 39/299 (13%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GGVYY +SRSLGA++G ++G++F+FA +A +++ F D + HG I + D
Sbjct: 127 GGVYYFISRSLGADWGGTIGVIFSFATTFSAVLHSFSFVDVVQ---AWHGGYITNGGKWD 183
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
I+ + ++ +I + E + L G L + + R K
Sbjct: 184 HEIIAISLIFILLLIICTSLKVECYMEYCLSALIGVAMIGFFFGLL---NKNTPRWK--- 237
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
+ ++ N ++ E +FF+VFAV+FP TG+ AGANI GDL +P +IP GT
Sbjct: 238 ---VSNLKNNLWASYLPGE----NFFTVFAVFFPGCTGIMAGANISGDLADPQKSIPVGT 290
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMS 246
+ A+ T +L+ + A+ AS N+ L + IM MS
Sbjct: 291 IGAI-------ITTTLLNMITAIILASAATKNV---------------LLTDTTIMCDMS 328
Query: 247 AWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLI-FFSKPYGRHGEPYRGY 304
WGP +Y G P+ Q+L D+I P + FF+ +P RG+
Sbjct: 329 LWGPLVYLGIIGAAVSSASAALIGGPKTFQSLCEDKILPKVFDFFAVGKASSNDPVRGF 387
Score = 68.9 bits (161), Expect = 5e-10
Identities = 42/172 (24%), Positives = 90/172 (52%), Gaps = 15/172 (8%)
Query: 595 VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIE 654
+D WWL +DGGL +L+ Y+++ K +R+F I + + + LL FRI+
Sbjct: 652 LDIWWLADDGGLTLLVGYLLSTHSAWKKCDIRLFTILPDGREITDVQVKLSKLLHLFRIK 711
Query: 655 YTELTLVRGIGDAPPESSWKMFNNIINDFKSEEKTDILTSEAELKSQYSKTSXXXXXXXX 714
++ +V+G+ + P E + + ND K + + D ++ + +++ K
Sbjct: 712 -AQILVVKGMSELPKEDMYAQW----NDCKIQAQND---TDTKAVNKFLK------LREF 757
Query: 715 XXQHSTKAAIVIITLPLPR-KVSASLYMAWLEVLSRDLPPVLFVRGNDSCVL 765
++S ++++I T+P+P+ V+ L+ + + +S +PP ++ RGN+ V+
Sbjct: 758 LMKYSDNSSLIICTIPIPKVNVTPELWTSLMGFVSDSMPPFIWSRGNNENVI 809
>UniRef50_Q9VJ75 Cluster: CG10413-PA; n=8; Endopterygota|Rep:
CG10413-PA - Drosophila melanogaster (Fruit fly)
Length = 941
Score = 103 bits (247), Expect = 2e-20
Identities = 85/310 (27%), Positives = 139/310 (44%), Gaps = 45/310 (14%)
Query: 3 ASERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIV-D 61
A E GGVY+++SR+LG EFG S+G LF FAN V ++M G + + G + D
Sbjct: 126 AIEGGGVYFMISRTLGLEFGGSIGTLFFFANVVGSAMAISGCTEGIMDNFGPRGHFVSGD 185
Query: 62 NDVNDIR----IVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGAL-IGPS 116
+ + D + ++ + ++C +G K + L +G +
Sbjct: 186 SHLPDGDWWRFLTSSMINTLQLLVCLVGAALFAKTSVIILATVTVCLFATYFSFLFVGAT 245
Query: 117 SDVERAKG------------FVGINLQTIRENWLPNFRY---SEGREHDFFSVFAVYFPA 161
++ G + G+N T+R+N ++ S G++ DF + F V F
Sbjct: 246 NNTIPVPGDNILSNTTTFLDYTGLNATTLRDNLGSHYGRDYTSNGKQVDFSTTFGVLFSG 305
Query: 162 VTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLTT 221
VTG+ AGAN+ G+LKNP+ +IP GTL A+A + SY +ILS
Sbjct: 306 VTGIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSY---IILS----------------- 345
Query: 222 AALESC-KPHCGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGV 280
L SC P+ + + NNY + ++ W PF G R+++AL
Sbjct: 346 -FLMSCTTPY--FTMQNNYLFLMPVNLWPPFTAIGILTATFSTSLSNLIGSSRILEALSK 402
Query: 281 DRIYPGLIFF 290
D+++ L+ F
Sbjct: 403 DQVFGSLLNF 412
Score = 56.0 bits (129), Expect = 4e-06
Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 1/129 (0%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
WGS ++ + ++ L R H + + PQ+L+L +P L+D + L K G +
Sbjct: 532 WGSISQALMFHQVRKYLLMLDPRKDHVKFWRPQILLLVSSPRSCCPLVDFVNDLKKSGLY 591
Query: 381 MIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGLGKL 440
I+ + E F+ + +++AF + ++ G L++ SG+G +
Sbjct: 592 -IIGHVKLGDFKGIEDAEDNQQWWSFLDHMRVKAFTEVTLSRSIREGVQHLIRLSGIGAM 650
Query: 441 SPNILLIGF 449
PN +++GF
Sbjct: 651 KPNTIILGF 659
>UniRef50_A6RLT2 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 1364
Score = 102 bits (244), Expect = 4e-20
Identities = 70/208 (33%), Positives = 101/208 (48%), Gaps = 12/208 (5%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGF--CDSLNHLLKTHGLKIVDNDV 64
GG YYL+SRSLG EFG S+G++F MN +G C +LN + +
Sbjct: 227 GGAYYLISRSLGPEFGGSIGLVFYLGFVFNTGMNAVGLIDCITLNFGADNGNWAHILPET 286
Query: 65 NDIRIVGAVALLVMC-VICAIGMDWETKAQNFLXXXXXXXXXXXXXGALI-GPSSDVERA 122
+ + +LV+C ++C G +A N L ALI P
Sbjct: 287 KWYCYLWSTVILVLCTLLCLAGSGIFARASNGLLVVLFIATLSIPLSALIVSPFESQNLG 346
Query: 123 KGFVGINLQTIRENWLPNFRYS------EGREHDFFSVFAVYFPAVTGVQAGANICGDLK 176
+ GI+L+T+ N LP GRE F +F + FPA G+ AGA++ GDLK
Sbjct: 347 IEYTGISLETLSGNLLPQLTRGAAGSQINGRE-TFQDLFGILFPATGGIFAGASMSGDLK 405
Query: 177 NPAVAIPKGTLLALAISVTSYFTMVILS 204
+P+ AIPKGT+ L I+ +T+VIL+
Sbjct: 406 SPSKAIPKGTVYGL-ITTFFLYTLVILA 432
Score = 51.2 bits (117), Expect = 1e-04
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 3/130 (2%)
Query: 320 SWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGS 379
SWG ++ Y ++ +L H + + PQ+++L P ++ LI + + K G
Sbjct: 612 SWGDVSQSLIYHQIRKYLLKLKQE--HVKFWRPQVILLVNDPRRQYKLIQFCNSMKK-GG 668
Query: 380 FMIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGLGK 439
I+ I T Q +++ + K++AF + L+ GA ++ +GLG
Sbjct: 669 LYILGHIIVTDDFSQSVPEAQAAWNKYIDFSKIKAFVNIAISPALEWGARNIILNAGLGG 728
Query: 440 LSPNILLIGF 449
+ PNI ++GF
Sbjct: 729 MRPNIAVMGF 738
>UniRef50_Q19301 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 574
Score = 100 bits (239), Expect = 2e-19
Identities = 69/207 (33%), Positives = 105/207 (50%), Gaps = 13/207 (6%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG+Y+LVS LG + G ++GI++AF AVA + +GF +S+ HL ++ KI+
Sbjct: 112 GGIYFLVSHVLGHQIGGAIGIIYAFGQAVATGLVAVGFGESVAHLFESES-KIM------ 164
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIG--PSSDVER-AK 123
I+ + + L+V+ + G+ W + Q L GAL P S V R +
Sbjct: 165 IKGIAILTLMVLTAVNTAGVTWVVRLQIVLLLTIALAVTDFIFGALFSSEPESGVFRFSS 224
Query: 124 GFVGINLQTIRE--NWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVA 181
+ +N + E N + E FF+VF V+F GV AG N+ GDLK+P +
Sbjct: 225 ERIRVNADSHYEAVNCSIIGIPRQIPEQSFFTVFGVFFANFLGVLAGVNMSGDLKDPHKS 284
Query: 182 IPKGTLLALAISVTSYFTMV-ILSGMG 207
IP G L A+ +S T F + IL G+G
Sbjct: 285 IPLGELSAVGVSSTICFIFIMILGGVG 311
>UniRef50_A6GE86 Cluster: Amino acid permease-associated region;
n=1; Plesiocystis pacifica SIR-1|Rep: Amino acid
permease-associated region - Plesiocystis pacifica SIR-1
Length = 1832
Score = 99 bits (238), Expect = 2e-19
Identities = 79/296 (26%), Positives = 128/296 (43%), Gaps = 45/296 (15%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YY+VSRSLG G ++G+ + + S+ IGFC+S + ++ +++
Sbjct: 73 GGPYYIVSRSLGLPIGGTLGLALFVGLSFSISLYVIGFCESFLAYWE------IEPTIDN 126
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
IRI G ++ + V+ I + K Q + P++
Sbjct: 127 IRIYGTGTIIALTVVTLISTSFAIKTQYVILGLIAASLFAIGLSPTAPPTA--------- 177
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
G++L EG E +F ++FPAVTG AG N+ GDL++P +IP GT
Sbjct: 178 GMHLTA-----------PEGAE-PIAVIFGIFFPAVTGFTAGVNMSGDLRDPKRSIPVGT 225
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMS 246
+ A+++ + Y T+ I D N N+ L +GL +YA++
Sbjct: 226 MAAISVGLVVYVTLAIFLAWKIPTDGLLNNTNI----LVDISSESLWGL-GSYAVV---- 276
Query: 247 AWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYR 302
G W PR++QAL DR+ P +FF+K +G+ EP R
Sbjct: 277 -------GGIWGATLSSGLGSILGAPRILQALSADRVTP--VFFAKGHGKDNEPRR 323
>UniRef50_Q9NQR5 Cluster: Cation-chloride cotransporter-interacting
protein; n=26; Eumetazoa|Rep: Cation-chloride
cotransporter-interacting protein - Homo sapiens (Human)
Length = 914
Score = 97.9 bits (233), Expect = 9e-19
Identities = 80/321 (24%), Positives = 137/321 (42%), Gaps = 45/321 (14%)
Query: 3 ASERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTH-----GL 57
A + GG Y+++SR+LG E G S+G++F AN +++ +G +S+ + GL
Sbjct: 98 AVQGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESVLDVFGADATGPSGL 157
Query: 58 KIVDNDVNDIRIVGAVALLVMCVICAIGMDWETKAQ--NFLXXXXXXXXXXXXXGALIGP 115
+++ + G++ L ++ +C +G +A FL A +GP
Sbjct: 158 RVLPQGYGWNLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLISFVA-VGP 216
Query: 116 -------------SSDVERAKGFVGINLQTIRENWLPNFR--YSEGREHDFFSVFAVYFP 160
SS R F G N T+++N + Y+ G +F +VFAV F
Sbjct: 217 RDIRLTPRPGPNGSSLPPRFGHFTGFNSSTLKDNLGAGYAEDYTTGAVMNFANVFAVLFN 276
Query: 161 AVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLT 220
TG+ AGAN+ G+LK+P+ AIP GT++A+A + Y + LS R
Sbjct: 277 GCTGIMAGANMSGELKDPSRAIPLGTIVAVAYTFFVYVLLFFLSSFTCDRTL-------- 328
Query: 221 TAALESCKPHCGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGV 280
L +Y + +S W P + G + R++ AL
Sbjct: 329 --------------LQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIGASRILHALAR 374
Query: 281 DRIYPGLIFFSKPYGRHGEPY 301
D ++ ++ +K R G P+
Sbjct: 375 DDLFGVILAPAKVVSRGGNPW 395
Score = 61.7 bits (143), Expect = 7e-08
Identities = 40/142 (28%), Positives = 68/142 (47%), Gaps = 4/142 (2%)
Query: 320 SWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGS 379
SWG ++ + ++ L R H + + PQLL+L G P L+ +A+ L K G
Sbjct: 500 SWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGNPRGALPLLRLANQLKK-GG 558
Query: 380 FMIVADIT--DTALTKGERVSRQH-IGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASG 436
++ +T D + V Q+ V +++AF L +++GA L++ SG
Sbjct: 559 LYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDRAQVKAFVDLTFSPSVRQGAQHLLRISG 618
Query: 437 LGKLSPNILLIGFKKDWTNAEH 458
LG + PN L++GF D +H
Sbjct: 619 LGGMKPNTLVLGFYDDAPPQDH 640
Score = 36.3 bits (80), Expect = 3.1
Identities = 37/146 (25%), Positives = 58/146 (39%), Gaps = 9/146 (6%)
Query: 621 HKLPLRIFAITKEQHKREFENKCMESLLKKFRI--EYTELTLVRGIGDAPPESSWKMFNN 678
H LRIF + + +LL + RI E E+ G G PE+ + +
Sbjct: 762 HSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVQEVVWGEGAGAGEPEAEEE--GD 819
Query: 679 IINDFKSEEKTDILTSEAE--LKSQYSK-TSXXXXXXXXXXQHSTKAAIVIITLPLPRKV 735
+N + + + + L A +++Q + T A+ + LP P
Sbjct: 820 FVNSGRGDAEAEALARSANALVRAQQGRGTGGGPGGPEGGDAEGPITALTFLYLPRPPAD 879
Query: 736 SASL--YMAWLEVLSRDLPPVLFVRG 759
A Y+A LE L+RDL P L V G
Sbjct: 880 PARYPRYLALLETLTRDLGPTLLVHG 905
>UniRef50_A1SVK2 Cluster: Amino acid permease-associated region;
n=1; Psychromonas ingrahamii 37|Rep: Amino acid
permease-associated region - Psychromonas ingrahamii
(strain 37)
Length = 847
Score = 96.7 bits (230), Expect = 2e-18
Identities = 82/298 (27%), Positives = 132/298 (44%), Gaps = 50/298 (16%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SR+LG EFG ++G++ A +V+ IGF + + GL +++ +
Sbjct: 81 GGDYYLISRTLGLEFGGALGLVLFMAQSVSIGFYCIGFGEVVA------GLFAMNDGI-- 132
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
+I+ VA+ + + G DW T+ Q + GAL+
Sbjct: 133 AQIIALVAIAGLFFLAWQGADWSTRFQYVVMAVICLALISFFMGALLH------------ 180
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
+ +R NW S + F+ +FAV+FPAVTG G ++ GDL +P ++PKGT
Sbjct: 181 -WDFALLRGNW-----QSAPQAPSFWVLFAVFFPAVTGFTQGVSMSGDLSDPGSSLPKGT 234
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMS 246
+A+ IS+ Y T + G+L L ++Y+ M +
Sbjct: 235 FMAVGISLIVYLTAALFFA-GSLPQQL---------------------LASDYSAMNRI- 271
Query: 247 AWGP-FIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYRG 303
AW P I AG + PR++Q+L D+++P L F+ G P RG
Sbjct: 272 AWLPVLIIAGVFAATLSSAMASFLGAPRILQSLASDKVFPLLTPFATGVGSSNNPQRG 329
Score = 43.6 bits (98), Expect = 0.020
Identities = 25/134 (18%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
W Q + ++S + H R + PQ+L + + +R L+ + L
Sbjct: 433 WADGRRSYHLQQVREHLLQISLELEHPRDWRPQILAFSSSRTRRERLLKFSSWLEAGSGL 492
Query: 381 MIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGLGKL 440
+ I + + + ++ + + E + ++AF +++ L+ G++ L+Q+ G+G L
Sbjct: 493 TTLVHILEKSPLQ-KKSAENELYED-ISASGVQAFPLVINAPSLEIGSSLLLQSFGIGPL 550
Query: 441 SPNILLIGFKKDWT 454
N +L+ + +T
Sbjct: 551 KANTILLNYLDSYT 564
>UniRef50_Q8CJI3-2 Cluster: Isoform 2 of Q8CJI3 ; n=2; Rattus
norvegicus|Rep: Isoform 2 of Q8CJI3 - Rattus norvegicus
(Rat)
Length = 585
Score = 95.9 bits (228), Expect = 4e-18
Identities = 59/173 (34%), Positives = 90/173 (52%), Gaps = 15/173 (8%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GGVY ++S LG + G +VG+L+ F VA +M GF +S++ LL GL ++
Sbjct: 103 GGVYSMISSVLGGQMGGTVGLLYVFGQCVAGAMYLTGFAESISDLL---GL----GNIWA 155
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
+R + LL + I G+ W + Q L ++G + ++ GF+
Sbjct: 156 VRGISVAVLLALLGINLAGVKWIIRLQLLLLSLLAVSTLDF----VVGSFTHLDPEHGFI 211
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPA 179
G + + ++ N LP YS G FF+VF V+FPA TGV AG N+ GDL+ PA
Sbjct: 212 GYSPELLQSNILP--EYSPG--ESFFTVFGVFFPAATGVMAGFNMGGDLREPA 260
>UniRef50_Q6CFS0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 1093
Score = 94.3 bits (224), Expect = 1e-17
Identities = 62/210 (29%), Positives = 94/210 (44%), Gaps = 12/210 (5%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YY++SRSLG EFG ++G++F F + A +N GFC + +
Sbjct: 136 GGAYYMISRSLGPEFGGAIGVVFFFGQVLNAGLNVAGFCQPILSSFGQNAGGFFPEGYW- 194
Query: 67 IRIVGAVALLVMCV-ICAIGMDWETKAQNFLXXXXXXXXXXXXXGAL-IGPSSDVERAKG 124
A +L+ C IC G ++A L + P +
Sbjct: 195 YEFFYATGVLLFCTSICMFGSGLFSQAGKVLFVILIVATVSVPLSVFFVKPFLVTKLDIW 254
Query: 125 FVGINLQTIRENWLPNFRYSE-------GREHDFFSVFAVYFPAVTGVQAGANICGDLKN 177
++G + +N LP F G+ F S+F V+FPA G+ AGA++ GDLK
Sbjct: 255 YMGPSWDVFSDNLLPRFTTGAVGSDLPPGQMETFTSLFGVFFPATAGIFAGASMSGDLKR 314
Query: 178 PAVAIPKGTLLALAISVTSYFTMVILSGMG 207
P+ +IPKGTL L ++ Y ++ GMG
Sbjct: 315 PSYSIPKGTLSGLGLTFILYAATIL--GMG 342
Score = 47.2 bits (107), Expect = 0.002
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 12/138 (8%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
WG ++ Y ++ L R H + + PQ+L+L P LI + L K G +
Sbjct: 519 WGDVSQALLYHQVRKYLLRL--RQDHVKFWRPQILLLVDDPRSAWGLIKFCNYLKKGGLY 576
Query: 381 MIVADITDTALTKGERVSRQHIGEQFVKYRKLR------AFYVLLQGLDLKRGANALMQA 434
++ +TK + + + + +Q + KLR AF + D+ GA +
Sbjct: 577 IL----GHVVITKDFQETFKEVKKQQQSWTKLRDMTGAKAFVQIACSPDVVWGARNVFLG 632
Query: 435 SGLGKLSPNILLIGFKKD 452
SGLG + PNI ++G +D
Sbjct: 633 SGLGGMKPNITILGSLRD 650
>UniRef50_A6PMX8 Cluster: Amino acid permease-associated region;
n=1; Victivallis vadensis ATCC BAA-548|Rep: Amino acid
permease-associated region - Victivallis vadensis ATCC
BAA-548
Length = 752
Score = 93.9 bits (223), Expect = 1e-17
Identities = 81/296 (27%), Positives = 128/296 (43%), Gaps = 45/296 (15%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SR LG FG S+G+ + ++A N +G +++ G ++
Sbjct: 82 GGAYYLISRVLGPSFGTSIGLTLFVSQSLAIPFNILGASEAI-----VSGWPVLRPWFPA 136
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
I + A+ ++ ++ G DW KAQ + L+GP +
Sbjct: 137 INL--ALGAMIFLLVWK-GADWAIKAQYVIMTVLGLSILFF----LLGPIGN-------- 181
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
+L+ +R NW +EG FA++FPAVTG+ AG N+ GDL+ P ++IP+GT
Sbjct: 182 -FSLENLRANW----GAAEGVT-SLIPYFAIFFPAVTGIMAGVNMSGDLRKPHISIPRGT 235
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMS 246
L AL ++ Y +I++ R+ E K Y + A+ L
Sbjct: 236 LYALGTAMGLYLVQIIVAAGCFPRE-------------EMIK--TPYLILTRNALFGL-- 278
Query: 247 AWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYR 302
G + AG PR++Q+LGVD + PG+ F G EP R
Sbjct: 279 --GFMVLAGVQAATLSTALGWALGAPRVLQSLGVDNVLPGIGMFRAGVGPQNEPRR 332
Score = 49.2 bits (112), Expect = 4e-04
Identities = 43/181 (23%), Positives = 85/181 (46%), Gaps = 9/181 (4%)
Query: 317 IDVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTK 376
+ +++G + G Y S + +L H +++ P + VL+G P++R ALID A + ++
Sbjct: 446 LSMTYGDARRGFVYSRIHSLLLQLPQLPLHPKNWRPTIAVLSGDPVRRGALIDYAILFSQ 505
Query: 377 IGSFMIVADITDTALTK--GERVSRQ-HIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQ 433
+ V I + T+ GER + Q + + R F ++ + ++Q
Sbjct: 506 RRGILSVIQIIISGDTRHIGERRTPQLQALRKLAQERDWPIFPSVVIAPEFDSALRIILQ 565
Query: 434 ASGLGKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAF-DLKLAVTILRVPGTSQTVQR 492
+ L + PNI+++G+ T AE +I ++ +Q D + +L T+ T QR
Sbjct: 566 SHSLDPIRPNIVMMGWP---TKAE--RIPPFFSHLQMIVEDFRRNALVLANERTTFTPQR 620
Query: 493 W 493
+
Sbjct: 621 Y 621
>UniRef50_UPI0001555D20 Cluster: PREDICTED: similar to
Melanoma-derived leucine zipper, extra-nuclear factor,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to Melanoma-derived leucine zipper,
extra-nuclear factor, partial - Ornithorhynchus anatinus
Length = 439
Score = 93.5 bits (222), Expect = 2e-17
Identities = 39/86 (45%), Positives = 64/86 (74%), Gaps = 1/86 (1%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDND-VN 65
GG Y+L+SRSLG E G S+G++FAFANAVA +M+T+GF ++L LL+ +G+++ + N
Sbjct: 32 GGTYFLISRSLGPELGGSIGLIFAFANAVAVAMHTVGFSETLCELLREYGVQLQQMEPQN 91
Query: 66 DIRIVGAVALLVMCVICAIGMDWETK 91
++R+VG V + ++ + GM+WE+K
Sbjct: 92 ELRVVGVVTVTILLGVALAGMEWESK 117
Score = 81.8 bits (193), Expect = 6e-14
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 8/173 (4%)
Query: 600 LYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIEYTELT 659
L +DGGL +L+PY++ RR + P+R+F + E N+ + SLL +FR+ + ++
Sbjct: 263 LSDDGGLTVLIPYLLTRRHKWARCPVRVFVSSAPGQLEEKRNE-IRSLLTRFRLGFQDVA 321
Query: 660 LVRGIGDAPPESSWKMFNNIINDFKSEEKTDILTSEAELKSQYS----KTSXXXXXXXXX 715
++ + P E S K F +++ + +E + L + E + + +
Sbjct: 322 VLPDLSGRPQEKSQKAFEDLVAPHRCQEPPEELEGQGEREGEPAPPPPPAGSISDRELQF 381
Query: 716 XQHSTKAAIVIITLPL-PRKV-SASLYMAWLEVLSRDL-PPVLFVRGNDSCVL 765
Q +LP+ PR +LYMAWLE LSR L PPV F+RGN L
Sbjct: 382 NQRKPLTQYSPRSLPVAPRTACPGALYMAWLETLSRGLAPPVAFIRGNQQDTL 434
Score = 60.5 bits (140), Expect = 2e-07
Identities = 24/53 (45%), Positives = 34/53 (64%)
Query: 433 QASGLGKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRVPG 485
+ SGLG+L PN+L++G+K DW + +Y GVI DA D V +LR+PG
Sbjct: 117 KVSGLGRLKPNVLVLGYKHDWQEEPSGAVEEYVGVIHDALDSNYGVCVLRMPG 169
>UniRef50_UPI00015B516A Cluster: PREDICTED: similar to cation
chloride cotransporter; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to cation chloride cotransporter -
Nasonia vitripennis
Length = 1423
Score = 92.3 bits (219), Expect = 4e-17
Identities = 84/310 (27%), Positives = 128/310 (41%), Gaps = 44/310 (14%)
Query: 3 ASERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDN 62
A E GG Y+++SR+LG EFG S+G LF AN V++++ G + L G + ++
Sbjct: 641 AVEGGGAYFMISRTLGPEFGGSIGTLFFMANVVSSALCISGCAEGLIENFGPSGYLVGEH 700
Query: 63 D-VNDIR----IVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSS 117
+ D R + +V ++C IG K + L+
Sbjct: 701 ALIPDGRWWRFLYCSVLNTANLLVCLIGAAMFAKTSVAILAIVCICLGSVFISFLVKGEM 760
Query: 118 DVE-------------RAKG-FVGINLQTIRENWLPNFRY---SEGREHDFFSVFAVYFP 160
+V G + G++ T+ N N+ S G DF SVF V F
Sbjct: 761 EVAIPDANSIVQNSTYHVNGSYTGLSTATLISNLYSNYSIDYTSHGIVSDFASVFGVLFS 820
Query: 161 AVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLT 220
VTG+ AGAN+ G+LKNP IP+GTL A+ + Y + IL
Sbjct: 821 GVTGIMAGANMSGELKNPGQNIPRGTLSAVLFTFICYIFLSIL----------------- 863
Query: 221 TAALESCKPHCGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGV 280
TAA S + L NN+ M ++ W PF+ G R+++AL
Sbjct: 864 TAATTS-----RFLLQNNFIYMMPINIWPPFVAVGILTATFSAGLSNLIGSSRVLEALAK 918
Query: 281 DRIYPGLIFF 290
D ++ L+ F
Sbjct: 919 DNVFGSLLNF 928
Score = 50.4 bits (115), Expect = 2e-04
Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 1/130 (0%)
Query: 336 FITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSFMIV-ADITDTALTKG 394
++ L R H + + PQ+L++ +P LID + L K G ++I + + +
Sbjct: 1021 YLLMLDSRKDHVKFWRPQILLMVASPRSACPLIDFINDLKKGGLYVIGHVKVGEFSGKVD 1080
Query: 395 ERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGLGKLSPNILLIGFKKDWT 454
+ V + K++AF L ++ G + L++ SG+G + PN +++GF D
Sbjct: 1081 PTIEEYPHWLSLVDHMKVKAFIELTVTRTVREGLHHLIRLSGMGAMKPNTIVLGFYDDEA 1140
Query: 455 NAEHKQISDY 464
+ Q S Y
Sbjct: 1141 PKDFFQNSQY 1150
>UniRef50_Q6BML2 Cluster: Debaryomyces hansenii chromosome F of
strain CBS767 of Debaryomyces hansenii; n=4;
Saccharomycetales|Rep: Debaryomyces hansenii chromosome
F of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 1323
Score = 91.5 bits (217), Expect = 8e-17
Identities = 56/219 (25%), Positives = 101/219 (46%), Gaps = 14/219 (6%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHG---LKIVDND 63
GG YY++SRSLG EFG ++G++F + AS+N +G + + H L+I+
Sbjct: 112 GGAYYMISRSLGPEFGGAIGVIFCIGQILNASLNVVGLIEPILVNFGEHNGDILQILPVG 171
Query: 64 VNDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALI----GPSSDV 119
+ ++ L + +G +K +L AL P
Sbjct: 172 YFWQALYCSIVLACCTGVALVGAKLVSKTAFYLFIILSLSTLSIPVSALFVKPFNPLPPP 231
Query: 120 ERAKGFVGINLQTIRENWLPNFR-------YSEGREHDFFSVFAVYFPAVTGVQAGANIC 172
+ + G + T+++N P+F + G + F ++F ++FP+ G+ AGA++
Sbjct: 232 HQNLAYTGFSWSTVKQNLWPHFTSGAAGSVLAPGEKESFKNLFGIFFPSTAGIFAGASMS 291
Query: 173 GDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRD 211
G+L NP+ +IP+GTL L ++ Y ++ G RD
Sbjct: 292 GELANPSKSIPQGTLKGLLLTFIFYSLVIASLGSTISRD 330
Score = 34.7 bits (76), Expect = 9.4
Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 13/113 (11%)
Query: 350 YNPQLLVLAGTPLQRPALIDVAHMLTKIGSFMI--VADITDTALTKGERV-----SRQHI 402
+ PQ+L+L P LI + L K G +++ V + D A + + S + I
Sbjct: 535 WRPQILLLCDDPRTSWNLIGFCNHLKKGGLYILGHVVVLNDEAKAENNELEFGINSYKEI 594
Query: 403 GEQFVKYRKLR------AFYVLLQGLDLKRGANALMQASGLGKLSPNILLIGF 449
+Q + KLR AF + G L G + SGLG + PNI ++GF
Sbjct: 595 QKQRHAWLKLRDMSNIKAFVQIALGPTLPWGVRNVYLGSGLGGMRPNITVLGF 647
>UniRef50_P38329 Cluster: Uncharacterized membrane protein YBR235W;
n=6; Saccharomycetales|Rep: Uncharacterized membrane
protein YBR235W - Saccharomyces cerevisiae (Baker's
yeast)
Length = 1120
Score = 91.1 bits (216), Expect = 1e-16
Identities = 65/213 (30%), Positives = 97/213 (45%), Gaps = 16/213 (7%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YY++SRSLG EFG S+G++F A MN +G + L + L + +
Sbjct: 128 GGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYNLGYSAQGEPPAALGE 187
Query: 67 IRIVG-------AVALLVMCVICA-IGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSD 118
+ G A +L +C A +G ++A N L ALI S
Sbjct: 188 LLPRGHWHEFTYATVILFLCFSVAFVGSQTVSRAGNILFLVLAASIFSIPLSALIR-SPF 246
Query: 119 VERAKGFVGINLQTIRENWLPNFRYS------EGREHDFFSVFAVYFPAVTGVQAGANIC 172
E + G + QT +N LP+ +G+E F +F V+FPA G+ AGA +
Sbjct: 247 TEGGISYTGPSWQTFHDNLLPHLTKGAAGSLLKGKE-TFNDLFGVFFPATAGIFAGAGMS 305
Query: 173 GDLKNPAVAIPKGTLLALAISVTSYFTMVILSG 205
+L+ P+ +IPKGTL L + Y +V G
Sbjct: 306 SELRKPSKSIPKGTLWGLLFTFICYAVVVFSMG 338
Score = 44.0 bits (99), Expect = 0.015
Identities = 39/161 (24%), Positives = 67/161 (41%), Gaps = 4/161 (2%)
Query: 320 SWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGS 379
SWG ++ Y ++ L R + + + PQ+L+ P LI + L K G
Sbjct: 510 SWGDVSQSLIYHQVRKYLLRL--RQDNIKYWRPQILLFVDNPRTSWNLIRFCNHLKKGGL 567
Query: 380 FMI--VADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
+++ VA D E ++Q + ++AF + G L G + SGL
Sbjct: 568 YILGHVAVTADFPKQLNELKTQQKAWMKIRDMAAIKAFVQVGTGPSLIWGIRNVFIGSGL 627
Query: 438 GKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAV 478
G + PNI ++GF + +H S +Q ++K V
Sbjct: 628 GGMKPNITVVGFFDLESYRKHIPQSRSQNNLQKQVEIKATV 668
>UniRef50_UPI00015A4CB0 Cluster: UPI00015A4CB0 related cluster; n=1;
Danio rerio|Rep: UPI00015A4CB0 UniRef100 entry - Danio
rerio
Length = 748
Score = 90.6 bits (215), Expect = 1e-16
Identities = 85/306 (27%), Positives = 138/306 (45%), Gaps = 25/306 (8%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YY++SRSLG EFG +VG+ F A +M +G ++ LL + +N+
Sbjct: 61 GGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILG---TIEILLAEDKADEAEALLNN 117
Query: 67 IRIVGAVALLVMCVICAIGMDWETK-AQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGF 125
+R+ G L +M ++ +G+ + K A FL L P + + F
Sbjct: 118 MRVYGTCCLTLMALVVFVGVKYVNKLALVFLACVLISFLLFIYLLNL--PETKKQHDIYF 175
Query: 126 VGINLQTIRENWLPNFRYSEGREHDFFSVFA-VYFPAVTGVQAGANICGDLKNPAVAIPK 184
N + ++ ++P Y FF++ +YFP+VTG+ AG+N GDL++ +IP
Sbjct: 176 FKFNHDSSQDKYMP---YVVNDITAFFTLLVGIYFPSVTGIMAGSNRSGDLRDAQRSIPI 232
Query: 185 GTLLALAIS--VTSYF-----TMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHN 237
GT+LA+A + + F +V+ + D+S ++ +L C G +
Sbjct: 233 GTILAIATTTIIVVLFGACIEGVVLRDKANSENDSSNDILQGINVSLIVCF-RFGDSVKG 291
Query: 238 NYAIMQLM--SAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYG 295
N I L S W I G + PRL+QA+ D I P L F +G
Sbjct: 292 NLVIGTLSWPSPW--VIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIVPFLEVFG--HG 347
Query: 296 R-HGEP 300
+ +GEP
Sbjct: 348 KANGEP 353
Score = 40.3 bits (90), Expect = 0.19
Identities = 16/59 (27%), Positives = 30/59 (50%)
Query: 595 VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRI 653
+D WW+ DGG+ +LLP+++ + K +RIF + + K ++ L R+
Sbjct: 690 IDVWWIVHDGGMLMLLPFLLRQHKVWKKCKMRIFTVAQMDDNSIQMKKDLQMFLYHLRL 748
Score = 36.3 bits (80), Expect = 3.1
Identities = 30/138 (21%), Positives = 59/138 (42%), Gaps = 9/138 (6%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYN-PQLLVLAGTP----LQRPALIDVAHMLT 375
WG G + L H+++++ PQ+LVL ++ P L+ L
Sbjct: 460 WGDGIRGLSLNAARYALIRLEEAPPHTKNWSRPQMLVLLNLDSELCVKHPRLLSFTTQLK 519
Query: 376 KIGSFMIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQAS 435
IV + + E Q+I + + K + F ++ +L+ G + L+Q++
Sbjct: 520 AGKGLTIVGSVLEGTYLSREN---QNI-KSAMAAEKTKGFCHVVVSSNLRDGISHLVQSA 575
Query: 436 GLGKLSPNILLIGFKKDW 453
GLG + N +L+ + +W
Sbjct: 576 GLGGMKHNSVLMAWPSNW 593
>UniRef50_Q4RQU3 Cluster: Chromosome 2 SCAF15004, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 2
SCAF15004, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 749
Score = 90.6 bits (215), Expect = 1e-16
Identities = 85/310 (27%), Positives = 126/310 (40%), Gaps = 46/310 (14%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAF---ANAVAASMNTIG-FCDSLNHLLKTHGLKIV-- 60
GG+Y ++S LG+ G +VG+L+ F + V N G C SL L G +
Sbjct: 132 GGIYSMISTVLGSRVGGTVGLLYVFGQVSRVVLLKKNESGNICSSLPTLQCVAGAMYITG 191
Query: 61 -DNDVND---------IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXG 110
V + +R + A LL + I G+ W + Q L
Sbjct: 192 FSESVAEVLGLQGQWAVRGLSAAVLLALLGINLAGVKWIVRLQLLLLAVLAVSTLDF--- 248
Query: 111 ALIGPSSDVERAKGFVGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGAN 170
+IG + ++ GFVG + + N +P+ Y+ G DFF+VF V+FPA TGV AG N
Sbjct: 249 -VIGTFTHLDPEHGFVGYSSWLLGSNAMPD--YTPG--EDFFTVFGVFFPAATGVMAGFN 303
Query: 171 ICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPH 230
+ DL+ P IP GTL A+ S Y V L G RDA
Sbjct: 304 MSSDLQRPENNIPVGTLAAVFTSWFLYLVFVFLLGAICTRDA------------------ 345
Query: 231 CGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFF 290
L ++ I + +S G G + PR++Q + +R+ P L F
Sbjct: 346 ----LRVDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQERVIPALAFL 401
Query: 291 SKPYGRHGEP 300
+ G + P
Sbjct: 402 GRGKGPNRTP 411
>UniRef50_A4AS86 Cluster: Na-K-Cl cotransporter, putative; n=1;
Flavobacteriales bacterium HTCC2170|Rep: Na-K-Cl
cotransporter, putative - Flavobacteriales bacterium
HTCC2170
Length = 731
Score = 88.2 bits (209), Expect = 7e-16
Identities = 76/294 (25%), Positives = 119/294 (40%), Gaps = 51/294 (17%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG+YY++SRS+G G S+GI A + ++ IGF +S N G+ VND
Sbjct: 72 GGIYYVLSRSMGIPIGGSIGIALYVGTAFSVALYLIGFAESFNSFF-GFGM-----SVND 125
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
R+ G +AL + V+ I K Q F+ G V
Sbjct: 126 FRLTGTIALCSLTVLALISTSLALKTQFFILAAIIVSLISIFLGTTEFAPQSVAMFSSEG 185
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
++L+ VFAV+FPAVTG AG + GDL++ +IP GT
Sbjct: 186 SVSLEV---------------------VFAVFFPAVTGFTAGIAMSGDLEDSKRSIPVGT 224
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMS 246
L A+ + Y + + A++S + L +Y I+ ++
Sbjct: 225 LAAIGTGLVVYIVLAVFMAF----------------AIDSEQ------LITDYNILMKIA 262
Query: 247 AWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEP 300
+ P + AG W PR++QA+ D++ P + F K G + EP
Sbjct: 263 LFAPAVVAGIWGATLSSALGGILGGPRILQAMSNDKVTPKI--FGKGRGVNNEP 314
>UniRef50_Q2UVJ5 Cluster: Cation chloride cotransporter; n=14;
Magnoliophyta|Rep: Cation chloride cotransporter -
Arabidopsis thaliana (Mouse-ear cress)
Length = 975
Score = 86.2 bits (204), Expect = 3e-15
Identities = 59/233 (25%), Positives = 105/233 (45%), Gaps = 26/233 (11%)
Query: 3 ASERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSL-----------NHL 51
A + GG YYL+ R+LG E G S+G+ F NAVA ++ +G ++ +
Sbjct: 193 AMKGGGPYYLIGRALGPEVGISIGLCFFLGNAVAGALYVLGAVETFLKAFPAAGIFRETI 252
Query: 52 LKTHGLKIVDN----DVNDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXX 107
K +G + ++ + +D+++ G V +++C I G+ +
Sbjct: 253 TKVNGTAVSESIQSPNSHDLQVYGIVVTILLCFIVFGGVKMINRVAPAFLVPVLLSIFCI 312
Query: 108 XXGALIGPSSDVERAKGFVGINLQTIRENWLPNFRYSE---------GREHDFFSVFAVY 158
G + + D + G G+ L++ ++NW ++ + G F + ++
Sbjct: 313 FIGIFLAKTDDPDN--GITGLRLKSFKDNWGSAYQMTNDAGIPDPTGGTYWSFNELVGLF 370
Query: 159 FPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRD 211
FPAVTG+ AG+N LK+ +IP GTL A + + Y V+ G A RD
Sbjct: 371 FPAVTGIMAGSNRSASLKDTQKSIPVGTLAATLTTTSLYLISVLFFGAVATRD 423
Score = 47.6 bits (108), Expect = 0.001
Identities = 38/173 (21%), Positives = 73/173 (42%), Gaps = 11/173 (6%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQ-------RPALIDVAHM 373
WG + +Q + + L H +++ P LV Q P L D A+
Sbjct: 596 WGDGFKSAYFQLALRSLRSLGANQVHPKNWYPIPLVFCRPWGQLPENVPCHPKLADFANC 655
Query: 374 LTKIGSFM-IVADITDTALTKGERVSRQHIGE--QFVKYRKLRAFYVLLQGLDLKRGANA 430
+ K G M I I D + +++ + +++Y++ ++ ++ G
Sbjct: 656 MKKKGRGMSIFVSILDGDYYECAEEAKEACKQLATYIEYKRCEGVAEIVVAPNMTEGFRG 715
Query: 431 LMQASGLGKLSPNILLIGFKKDWTNAEHKQI-SDYYGVIQDAFDLKLAVTILR 482
++Q GLG L PNI+++ + + W +I S + G+I D AV I++
Sbjct: 716 IIQTMGLGNLKPNIVVMRYPEIWRRENLTEIPSTFVGIINDCITANKAVVIIK 768
Score = 45.6 bits (103), Expect = 0.005
Identities = 41/187 (21%), Positives = 85/187 (45%), Gaps = 19/187 (10%)
Query: 592 KQY--VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLK 649
+QY +D +W+ DGGL +LL ++ + +++F I +E E ++ L
Sbjct: 779 RQYGTIDLYWIVRDGGLMLLLSQLLLTKESFESCKIQLFCIAEEDSDAEALKADVKKFLY 838
Query: 650 KFRI--EYTELTL----VRGIGDAPPES------SWKMFNNIINDFKSEEKTDILTSEAE 697
R+ E +T+ +R G++ +S + + ++ + + K + +L +
Sbjct: 839 DLRMHAEVIVVTMKSWDIRSEGNSQEDSLEAFDAAQRRISDYLGEIKRQGSNPLLANGKP 898
Query: 698 L---KSQYSK-TSXXXXXXXXXXQHSTKAAIVIITL-PLPRKVSASLYMAWLEVLSRDLP 752
+ + Q K +S AA+V+++L P P A YM ++++L ++P
Sbjct: 899 MVVNEQQVEKFLYTMLKLNSTILSYSRMAAVVLVSLPPPPLNHPAYFYMEYMDLLVENVP 958
Query: 753 PVLFVRG 759
+L VRG
Sbjct: 959 RMLIVRG 965
>UniRef50_Q6ZP54 Cluster: CDNA FLJ26488 fis, clone KDN05770, highly
similar to Bumetanide- sensitive
sodium-(potassium)-chloride cotransporter 2; n=2; Homo
sapiens|Rep: CDNA FLJ26488 fis, clone KDN05770, highly
similar to Bumetanide- sensitive
sodium-(potassium)-chloride cotransporter 2 - Homo
sapiens (Human)
Length = 342
Score = 86.2 bits (204), Expect = 3e-15
Identities = 45/134 (33%), Positives = 72/134 (53%), Gaps = 2/134 (1%)
Query: 323 SSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSFMI 382
SST+ Y + EL+ H +++ PQ +VL G P+ RPAL+D+ H TK I
Sbjct: 47 SSTQALSYVSALDNALELTTVEDHVKNFRPQCIVLTGGPMTRPALLDITHAFTKNSGLCI 106
Query: 383 VADIT--DTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGLGKL 440
++ L E S + ++ K++AFY + + G +L+QASGLG++
Sbjct: 107 CCEVFVGPRKLCVKEMNSGMAKKQAWLIKNKIKAFYAAVAADCFRDGVRSLLQASGLGRM 166
Query: 441 SPNILLIGFKKDWT 454
PN L+IG+KK+W+
Sbjct: 167 KPNTLVIGYKKNWS 180
Score = 52.8 bits (121), Expect = 3e-05
Identities = 23/61 (37%), Positives = 32/61 (52%)
Query: 244 LMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYRG 303
++S +GP I AG + P++ QAL D Y L FF+K YG++ EP RG
Sbjct: 181 MVSGFGPLITAGIFSATLSSALASLVSAPKVFQALCKDNFYKALQFFAKGYGKNNEPLRG 240
Query: 304 Y 304
Y
Sbjct: 241 Y 241
>UniRef50_Q4RZ03 Cluster: Chromosome 16 SCAF14974, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 16
SCAF14974, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 360
Score = 79.8 bits (188), Expect = 3e-13
Identities = 62/225 (27%), Positives = 101/225 (44%), Gaps = 21/225 (9%)
Query: 12 LVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND----I 67
++SR+LG EFG S+GI+F AN +++ +G +++ HG + + V
Sbjct: 136 MISRALGPEFGGSIGIMFFLANVCGSALYVLGLVEAIVDTFGKHGAALSAHHVLPSGYWY 195
Query: 68 RIVGAVALLVMCV-ICAIGMDWETKAQN--FLXXXXXXXXXXXXXGA-------LIGPSS 117
++ A + ++C+ +C +G KA FL A L PS
Sbjct: 196 SLLYATGIALLCLLVCLVGAHIYAKATFLIFLVVMFVLGTIFVSFFAVHPRTITLPSPSP 255
Query: 118 D-----VERAKGFVGINLQTIREN-WLP-NFRYSEGREHDFFSVFAVYFPAVTGVQAGAN 170
+ F G L T+ N W + Y+ F +VFAV F TG+ AG+N
Sbjct: 256 NGTDPAFPTTANFTGFKLNTLLGNLWAGYSLDYTTKTMMTFATVFAVMFNGCTGIMAGSN 315
Query: 171 ICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGN 215
+ G+LKNP+ AIP+GT+ A+ + Y + +L R G+
Sbjct: 316 MSGELKNPSYAIPRGTITAVIFTFIIYILLCVLVACSCDRLVKGS 360
>UniRef50_A2E1M7 Cluster: Amino acid permease family protein; n=5;
Trichomonas vaginalis G3|Rep: Amino acid permease family
protein - Trichomonas vaginalis G3
Length = 867
Score = 79.0 bits (186), Expect = 4e-13
Identities = 60/204 (29%), Positives = 101/204 (49%), Gaps = 23/204 (11%)
Query: 562 EALRSANFSRTSRRKLSNGALSFRALSFNCKQYVDAWWLYEDGGLNILLPYIIARRGYKH 621
E ANFS T R L+ F+ + N +D WWL +DGGL +LLPY+++R
Sbjct: 673 ETAFDANFSVTVLRHLNR----FKEVDRNGT--IDVWWLADDGGLTLLLPYLLSREKQWK 726
Query: 622 KLPLRIFAITKEQHKREFE--NKCMESLLKKFRIEYTELTLVRGIGDAPPE--SSWKMFN 677
LRI ++ ++F+ + ME LL KFRI+ + + + + P + K +
Sbjct: 727 NAKLRIMTLSFLDENQDFQETQERMEHLLYKFRIKAEVICIEVSVNNEEPSLLAKQKWQS 786
Query: 678 NIINDFKSEEKTDILTSEAELKSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLPRKVS- 736
+ N E +ILT+ L S + +S ++ + +T+ +PR+ +
Sbjct: 787 LVGNSIPENEHHNILTTRYLLLSDLIR------------NYSAMSSFICLTMLVPRETTI 834
Query: 737 ASLYMAWLEVLSRDLPPVLFVRGN 760
++Y++WL++LS P LFVRGN
Sbjct: 835 PNIYISWLDILSFLDVPFLFVRGN 858
Score = 50.8 bits (116), Expect = 1e-04
Identities = 53/231 (22%), Positives = 92/231 (39%), Gaps = 15/231 (6%)
Query: 5 ERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDV 64
++GG YYL+SRS G + A++G L +A + S N ++L + +
Sbjct: 160 QKGGCYYLISRSFGTNYAAAIGFLIILGHASSISSNFFNIGHVCSNLYSPK--LMTKSRY 217
Query: 65 NDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKG 124
D ++ +A V+ + G+ + L G + S A G
Sbjct: 218 GDSILIQFIACSVVLLFQFFGVKFLVILICILAAGLALGVCFLYAGFFVQKPS----ADG 273
Query: 125 FV-GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIP 183
F G + ++NW P G + D +F + F +V GV A+ G L AIP
Sbjct: 274 FYQGFSKALFKQNWKP-----AGAKFD-LELFYL-FSSVNGVITIADYSGSLSPAKQAIP 326
Query: 184 KGTLLALAISVTSYFTMV-ILSGMGALRDASGNVANLTTAALESCKPHCGY 233
G AL + + M+ ++SG + +VA+ T + + G+
Sbjct: 327 IGGYSALVTATVFFLLMLFLISGSANFENLPDSVASFMTISSHPLISYIGF 377
Score = 49.6 bits (113), Expect = 3e-04
Identities = 38/165 (23%), Positives = 63/165 (38%), Gaps = 5/165 (3%)
Query: 320 SWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLL-VLAGTPLQRPALIDVAHMLTKIG 378
SWGS + T+ L + H ++Y ++ V P ID + L
Sbjct: 525 SWGSVLSNHVFYSTMKEALRLYNVQPHVKTYRSNMIFVTQKKPNDCMHAIDFINQLLNGH 584
Query: 379 SFMIVADITDTALTKGERVSRQHIGEQFVKYR-KLRAFYVLLQGLDLKRGANALMQASGL 437
V + T + + E F+ FY + G + +G+
Sbjct: 585 GMAAVGRVVVTNEPPNIKKLIEERAESFITADDSYHVFYDIACAPTFHEGVRDFLLTAGI 644
Query: 438 GKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILR 482
G L PN L + F DW N + S+++ ++ AFD +VT+LR
Sbjct: 645 GTLRPNTLCLEFPDDWRNDDS---SEFFTTLETAFDANFSVTVLR 686
>UniRef50_UPI0000F207D5 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 652
Score = 78.6 bits (185), Expect = 6e-13
Identities = 34/106 (32%), Positives = 67/106 (63%), Gaps = 2/106 (1%)
Query: 378 GSFMIVADITDTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
GS ++ ++ + + +S H+ +++ RK+++FY + DL+ G L+Q++GL
Sbjct: 164 GSSVLCEGLSGPSPGTADSMSSTHL--KWLNNRKIKSFYHTVVADDLRTGVQMLLQSTGL 221
Query: 438 GKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILRV 483
G++ PN+L++G+KK+W + I +Y G++ DAFDL+ V +LR+
Sbjct: 222 GRMKPNVLVMGYKKNWRKVQPGIIENYVGILHDAFDLQYGVCVLRM 267
Score = 58.4 bits (135), Expect = 7e-07
Identities = 25/93 (26%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Query: 592 KQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKF 651
K+ +D +WL +DGGL +L+PY++ R+ + +R+F + E + E + K ++ L+ +F
Sbjct: 330 KKTIDVYWLSDDGGLTLLIPYLLTRKKRWGRCKVRVF-VGGEAQQIEEQKKELKGLISRF 388
Query: 652 RIEYTELTLVRGIGDAPPESSWKMFNNIINDFK 684
R+ + ++ ++ I AP + F + I ++
Sbjct: 389 RLGFKDIQVLPDINGAPQSEHIRKFEDFIAPYR 421
>UniRef50_Q8THK8 Cluster: Na-K-Cl cotransporter; n=3; cellular
organisms|Rep: Na-K-Cl cotransporter - Methanosarcina
acetivorans
Length = 758
Score = 75.4 bits (177), Expect = 5e-12
Identities = 51/150 (34%), Positives = 70/150 (46%), Gaps = 23/150 (15%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALR 210
F+ VFAVYFPA TG+ AGAN+ G+LK P +IP GTL + IS+ Y + + A
Sbjct: 230 FWEVFAVYFPAATGIMAGANMSGELKTPRKSIPLGTLSVIGISLCIYLALAYWFALSATP 289
Query: 211 DASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXX 270
+ L +NY I+ +A+GP + AG
Sbjct: 290 EE----------------------LVSNYTIIFEKAAFGPIVVAGLLGATFSSALNSIVG 327
Query: 271 VPRLIQALGVDRIYPGLIFFSKPYGRHGEP 300
PR++QALG I P +FS+ R GEP
Sbjct: 328 APRILQALGEHGILPKSEWFSQKTDR-GEP 356
Score = 36.3 bits (80), Expect = 3.1
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIG 43
GG + ++S+SLG E G S+GI + A+A SM G
Sbjct: 108 GGAFSIISQSLGLEVGGSIGIPLYLSQALAVSMYIFG 144
>UniRef50_A2FYU8 Cluster: Amino acid permease family protein; n=1;
Trichomonas vaginalis G3|Rep: Amino acid permease family
protein - Trichomonas vaginalis G3
Length = 804
Score = 74.5 bits (175), Expect = 1e-11
Identities = 51/171 (29%), Positives = 88/171 (51%), Gaps = 20/171 (11%)
Query: 594 YVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQ--HKREFENKCMESLLKKF 651
Y+D WWL++DGGL++L+ I+A PLR+F++ + + K + LL++F
Sbjct: 641 YIDLWWLFDDGGLSLLIASILA----GSSRPLRVFSVAQTDLGQNTQKHYKKIRHLLRQF 696
Query: 652 RIEYTELTLVRGIGDAPPES-SWKMFNNIINDFKSEEKTDILTSEAELKSQYSKTSXXXX 710
R+ + + D+ P S S +++N + + D LT + +L + +
Sbjct: 697 RVNAQVMAVSLSESDSIPSSRSQRLWNEMTVGLDEARQYDGLTKKYQLLADLIR------ 750
Query: 711 XXXXXXQHSTKAAIVIITLPLPR-KVSASLYMAWLEVLSRDLPPVLFVRGN 760
Q+S++A II+LP+PR V +Y W+ ++S PVLFVRGN
Sbjct: 751 ------QYSSEAITCIISLPVPRVDVPQVIYSRWISLISVMPIPVLFVRGN 795
Score = 68.5 bits (160), Expect = 6e-10
Identities = 69/280 (24%), Positives = 106/280 (37%), Gaps = 38/280 (13%)
Query: 5 ERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDV 64
E GG YY +SR+LG G + G + + AN A+ IG +++ L + K + +
Sbjct: 122 EAGGPYYTISRTLGPAIGGTAGFILSVANMHGAAAAHIGLAETIVIL---YSPKSLISTK 178
Query: 65 NDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKG 124
D R++ +++ + G + F+ LI P V +A+
Sbjct: 179 WDTRLIACTLTVIVAFLSRYGFEIR-----FITFFFIMIGLAAYILGLIFPY--VTKARD 231
Query: 125 FVGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPK 184
+ + NW + FF F++ FPA G+ AG+N G LK P +IP
Sbjct: 232 IIDCSENRFSVNWA-----THENTVSFFYTFSIIFPAFGGILAGSNGSGALKRPQRSIPL 286
Query: 185 GTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHN-NYAIMQ 243
GT+ AL Y LTT L C H GL N N +I Q
Sbjct: 287 GTITALVSGTVIYL--------------------LTTLTLTGC--HMSSGLINKNRSITQ 324
Query: 244 LMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRI 283
W P I+ + P +++ L D I
Sbjct: 325 ETGIWWPIIFVSIFLSVISKGVTGLGSGPMILRLLAGDGI 364
>UniRef50_Q9H7Q7 Cluster: FLJ00010 protein; n=9; Eutheria|Rep:
FLJ00010 protein - Homo sapiens (Human)
Length = 772
Score = 72.1 bits (169), Expect = 5e-11
Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 24/179 (13%)
Query: 125 FVGINLQTIRENWLPNFR--YSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAI 182
F G N T+++N + Y+ G +F SVFAV F TG+ AGAN+ G+LK+P+ AI
Sbjct: 97 FTGFNSSTLKDNLGAGYAEDYTTGAVMNFASVFAVLFNGCTGIMAGANMSGELKDPSRAI 156
Query: 183 PKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIM 242
P GT++A+A + Y + LS R L +Y
Sbjct: 157 PLGTIVAVAYTFFVYVLLFFLSSFTCDRTL----------------------LQEDYGFF 194
Query: 243 QLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPY 301
+ +S W P + G + R++ AL D ++ ++ +K R G P+
Sbjct: 195 RAISLWPPLVLIGIYATALSASMSSLIGASRILHALARDDLFGVILAPAKVVSRGGNPW 253
Score = 62.1 bits (144), Expect = 5e-08
Identities = 40/142 (28%), Positives = 68/142 (47%), Gaps = 4/142 (2%)
Query: 320 SWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGS 379
SWG ++ + ++ L R H + + PQLL+L G P L+ +A+ L K G
Sbjct: 358 SWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGNPRGALPLLRLANQLKK-GG 416
Query: 380 FMIVADIT--DTALTKGERVSRQH-IGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASG 436
++ +T D + V Q+ V +++AF L +++GA L++ SG
Sbjct: 417 LYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDRAQVKAFVDLTLSPSVRQGAQHLLRISG 476
Query: 437 LGKLSPNILLIGFKKDWTNAEH 458
LG + PN L++GF D +H
Sbjct: 477 LGGMKPNTLVLGFYDDAPPQDH 498
Score = 36.3 bits (80), Expect = 3.1
Identities = 37/146 (25%), Positives = 58/146 (39%), Gaps = 9/146 (6%)
Query: 621 HKLPLRIFAITKEQHKREFENKCMESLLKKFRI--EYTELTLVRGIGDAPPESSWKMFNN 678
H LRIF + + +LL + RI E E+ G G PE+ + +
Sbjct: 620 HSARLRIFLCLGPREAPGAAEGRLRALLSQLRIRAEVQEVVWGEGAGAGEPEAEEE--GD 677
Query: 679 IINDFKSEEKTDILTSEAE--LKSQYSK-TSXXXXXXXXXXQHSTKAAIVIITLPLPRKV 735
+N + + + + L A +++Q + T A+ + LP P
Sbjct: 678 FVNSGRGDAEAEALARSANALVRAQQGRGTGGGPGGPEGGDAEGPITALTFLYLPRPPAD 737
Query: 736 SASL--YMAWLEVLSRDLPPVLFVRG 759
A Y+A LE L+RDL P L V G
Sbjct: 738 PARYPRYLALLETLTRDLGPTLLVHG 763
>UniRef50_A6DJU2 Cluster: Na-K-Cl cotransporter, putative; n=1;
Lentisphaera araneosa HTCC2155|Rep: Na-K-Cl
cotransporter, putative - Lentisphaera araneosa HTCC2155
Length = 750
Score = 71.3 bits (167), Expect = 9e-11
Identities = 59/202 (29%), Positives = 97/202 (48%), Gaps = 19/202 (9%)
Query: 5 ERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDV 64
E+GGV+ LV ++LG E G ++GI FA A++A+M G + L ++ D +
Sbjct: 90 EKGGVFTLVGQTLGLEIGGAIGIPLYFAQAMSAAMYLHGMKEGWLSLFPAERMQ--DTFM 147
Query: 65 NDIRIVGAVA--LLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERA 122
I G ++V CAIG+ + F ++
Sbjct: 148 APIVEAGIYESFMVVAFFFCAIGLTLISTRVAFKVQNLVMVFIVVALSSM---------- 197
Query: 123 KGFVGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAI 182
F+G+++ + L +++G + F S+FAV+FPA TGV GA++ G LK+P +I
Sbjct: 198 --FLGLSVHEWQTPQLIG-DFADG--NSFKSLFAVFFPAATGVMVGASMSGSLKDPRRSI 252
Query: 183 PKGTLLALAISVTSYFTMVILS 204
KGTL A IS Y ++ +L+
Sbjct: 253 TKGTLGAWGISFVVYASVAVLA 274
>UniRef50_A1ZYX4 Cluster: Solute carrier family 12
(Potassium/chloride transporters), member 7, putative;
n=1; Microscilla marina ATCC 23134|Rep: Solute carrier
family 12 (Potassium/chloride transporters), member 7,
putative - Microscilla marina ATCC 23134
Length = 1821
Score = 70.1 bits (164), Expect = 2e-10
Identities = 47/148 (31%), Positives = 68/148 (45%), Gaps = 25/148 (16%)
Query: 154 VFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRDAS 213
+F V+FPAVTG AG + GDLKNP IP GT+ ++ + + Y + I
Sbjct: 274 IFGVFFPAVTGFTAGVAMSGDLKNPKRTIPVGTMASIVVGLVVYIVLSIFLAY------- 326
Query: 214 GNVANLTTAALESCKPHCGYGLHNNYAIMQLMSAWGP-FIYAGCWXXXXXXXXXXXXXVP 272
+ PH L NN I++ ++ P F+ AG W P
Sbjct: 327 ------------TIDPHI---LRNNSNILKEIAFISPAFVLAGIWGATLSSALGGILGAP 371
Query: 273 RLIQALGVDRIYPGLIFFSKPYGRHGEP 300
R++QA+ VD+I P L F K G++ EP
Sbjct: 372 RILQAMSVDKITPKL--FGKGVGKNNEP 397
Score = 43.2 bits (97), Expect = 0.027
Identities = 21/59 (35%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
Query: 5 ERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDS-LNHLLKTHGLKIVDN 62
+ GG+YY++SRSLG G ++GI A++ ++ IGF +S L+ + G +I +N
Sbjct: 70 QAGGLYYILSRSLGLPIGGAIGITLFVGTALSIALYAIGFSESFLDFIGMASGHQINEN 128
>UniRef50_Q21977 Cluster: Temporarily assigned gene name protein
158; n=4; Chromadorea|Rep: Temporarily assigned gene
name protein 158 - Caenorhabditis elegans
Length = 1003
Score = 67.7 bits (158), Expect = 1e-09
Identities = 50/153 (32%), Positives = 70/153 (45%), Gaps = 15/153 (9%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALR 210
FF + A+YFPAVTG+ GAN+ GDLKNP +IP GT+ A + YF++ + G GA
Sbjct: 329 FFVLLAIYFPAVTGIFTGANMSGDLKNPQASIPAGTIAANLTTSFVYFSLAFIFG-GA-- 385
Query: 211 DASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXX 270
+ A L K G A++ S W + G +
Sbjct: 386 --------IDNAVLRD-KNGQSVGGQMVVALLSWPSPW--VLLIGSFLSTFGAALQCLCS 434
Query: 271 VPRLIQALGVDRIYPGLIFFSKPYGRHGEPYRG 303
PRL+QA+ D + P L F K + EP+ G
Sbjct: 435 APRLLQAIAKDEVIPLLSPFKK-VTANNEPFLG 466
Score = 54.8 bits (126), Expect = 8e-06
Identities = 32/92 (34%), Positives = 47/92 (51%), Gaps = 10/92 (10%)
Query: 5 ERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSL----------NHLLKT 54
E GG Y+++SR+LG EFG++VGILF AN VA SM +G + L +
Sbjct: 97 ESGGAYFMISRNLGPEFGSAVGILFYLANTVATSMYLVGGVEILLLYIFPGLTFGGVEGQ 156
Query: 55 HGLKIVDNDVNDIRIVGAVALLVMCVICAIGM 86
H + N +R + LL+ I A+G+
Sbjct: 157 HDTSMFGTMTNSLRFYSTILLLIEFAIVAMGV 188
Score = 39.5 bits (88), Expect = 0.33
Identities = 17/78 (21%), Positives = 37/78 (47%)
Query: 577 LSNGALSFRALSFNCKQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHK 636
++ G + F + F +D +W+ DGGL +L+ Y++ + LR+ I +E
Sbjct: 742 VAKGIIDFPSAVFRMSGMIDVYWIVHDGGLCLLMGYLLKQHKVWRGCKLRVIGIAQESDN 801
Query: 637 REFENKCMESLLKKFRIE 654
+ ++ + + RI+
Sbjct: 802 NVKMQEDLQKYVYQLRID 819
Score = 37.1 bits (82), Expect = 1.8
Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 17/144 (11%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHM-LTKIGS 379
WG G + ++ + H +++ PQLL+L + +IDV ++ L + S
Sbjct: 570 WGDGIRGLALTTAQYSLMKIEDKEPHPKNWRPQLLLLLSMQWSKE-IIDVRYLNLLNLAS 628
Query: 380 FMIVAD--ITDTALTKGERVSR--QHIGEQFVKYR--------KLRAFY-VLLQGLDLKR 426
+ TA +G+ S + GEQ VK R +LR F L+ D R
Sbjct: 629 QLKAGKGLTVVTAFLQGDPTSPDDKKKGEQ-VKARMDFDMNQVRLRGFAKTLVHSEDQVR 687
Query: 427 GA-NALMQASGLGKLSPNILLIGF 449
G+ + L+Q+ GLG L PN +LI +
Sbjct: 688 GSMSTLVQSVGLGGLKPNTMLISW 711
Score = 35.9 bits (79), Expect = 4.1
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 686 EEKTDILTSEAELKSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLP--RKVSASL--YM 741
E KT +A +S+ SK QHS + ++++ LP P K +L Y+
Sbjct: 916 ETKTKKERMKALDRSKVSKMHTAVRLNELLLQHSANSQLILLNLPKPPVHKDQQALDDYV 975
Query: 742 AWLEVLSRDLPPVLFVRGNDSCVL 765
+LEV++ L V+FVRG V+
Sbjct: 976 HYLEVMTDKLNRVIFVRGTGKEVI 999
>UniRef50_Q4T0H4 Cluster: Chromosome undetermined SCAF11052, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF11052,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 482
Score = 66.9 bits (156), Expect = 2e-09
Identities = 29/93 (31%), Positives = 59/93 (63%), Gaps = 1/93 (1%)
Query: 592 KQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKF 651
K+ +D +WL +DGGL +LLPY++ RR + +R+F + K+E + + + +L+KKF
Sbjct: 113 KKTIDVYWLSDDGGLTLLLPYLLTRRRRWARCKVRVF-VGGTVEKKETQKEEIVALIKKF 171
Query: 652 RIEYTELTLVRGIGDAPPESSWKMFNNIINDFK 684
R+ + ++ ++ I +P + + F N+++DF+
Sbjct: 172 RLGFNDVEVLPDIYQSPQPENVQRFENMLSDFR 204
Score = 57.6 bits (133), Expect = 1e-06
Identities = 23/52 (44%), Positives = 35/52 (67%)
Query: 431 LMQASGLGKLSPNILLIGFKKDWTNAEHKQISDYYGVIQDAFDLKLAVTILR 482
++Q +GL +L PN++L+GFK DW + +Y ++QDAFDL+ V ILR
Sbjct: 6 VLQGAGLSRLKPNVMLMGFKSDWRSDSPHAAHNYVAILQDAFDLQYGVCILR 57
>UniRef50_A2DUG3 Cluster: Amino acid permease family protein; n=1;
Trichomonas vaginalis G3|Rep: Amino acid permease family
protein - Trichomonas vaginalis G3
Length = 863
Score = 66.9 bits (156), Expect = 2e-09
Identities = 51/188 (27%), Positives = 81/188 (43%), Gaps = 11/188 (5%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG+YYL+SR+LG E G + G++ A+ A S + + SL ++ + K + N
Sbjct: 148 GGLYYLLSRTLGPEIGGATGLILVIAHTTAISFR-LTYTASL--IIDFYSPKFLTNSARW 204
Query: 67 IRIVGAVAL-LVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGF 125
R + V L++ + G+ FL G I + E F
Sbjct: 205 DRTLWQVIFNLILFFVSLFGIGTIFYLMVFLFVLLLAGVLVFFLGFFIRKPNSTE---FF 261
Query: 126 VGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKG 185
G++L T+R NF E ++F + FPA + AN G+L P AIP G
Sbjct: 262 TGLSLSTLRN----NFGLQHVHEPGILAIFGILFPASNAIMTCANFSGNLNPPRCAIPIG 317
Query: 186 TLLALAIS 193
+++ IS
Sbjct: 318 GFVSMLIS 325
Score = 47.6 bits (108), Expect = 0.001
Identities = 32/145 (22%), Positives = 59/145 (40%), Gaps = 4/145 (2%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGT-PLQRPALIDVAHMLTKIGS 379
WG+ T+ + + T+ L H H +++ P ++++ P QR ID +ML
Sbjct: 514 WGTVTQSKTFYQTLKEELALYHVQPHPKTFRPNIILITTLHPDQRHPTIDFLNMLLHNNG 573
Query: 380 FMIVA--DITDTALT-KGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASG 436
V I D A +++ + + FY + G L+ G
Sbjct: 574 MAAVGRVHIVDEATNFTFKQLVEERESTYLTTQNGYKMFYDVTSAKTFVEGVTDLILMMG 633
Query: 437 LGKLSPNILLIGFKKDWTNAEHKQI 461
+G++ PN L + F +DW + + I
Sbjct: 634 IGRMRPNTLCLVFPEDWKDTQFVDI 658
Score = 42.3 bits (95), Expect = 0.047
Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 15/181 (8%)
Query: 585 RALSFNCKQYVDAWWLYEDGGLNILLPYIIARR-GYKHKLPLRIFAIT--KEQHKREFEN 641
+ LS K ++D WW G ++L Y++++ +K LR+ + + E
Sbjct: 684 KLLSEITKGFIDVWWNINGSGFTLILAYLLSKSPKWKKITSLRVITVADLDAGANAQEEE 743
Query: 642 KCMESLLKKFRIEYTELTLVRGIG-DAPPESSWKMFNNIINDFKSEEKTDILTSEAELKS 700
+ +LL KFRI +TL I D P + +N I + + + E+K
Sbjct: 744 VNLANLLYKFRITADVMTLETSISQDEPTPLTINRWNEICT---AVGENPNYSDNLEIKR 800
Query: 701 QYSKTSXXXXXXXXXXQHSTKAAIVIITLP-LPRKVSASLYMAWLEVLSRDLPPVLFVRG 759
+S+ A+ + + +P P VS +LYMA L++++ P V+
Sbjct: 801 SLLMADLVRT-------YSSNASAIFMLIPNRPPGVSKNLYMAQLDLMTEVNRPFCIVKQ 853
Query: 760 N 760
N
Sbjct: 854 N 854
>UniRef50_Q09573 Cluster: Sodium/chloride cotransporter type 2; n=1;
Caenorhabditis elegans|Rep: Sodium/chloride
cotransporter type 2 - Caenorhabditis elegans
Length = 1020
Score = 64.5 bits (150), Expect = 1e-08
Identities = 36/92 (39%), Positives = 55/92 (59%), Gaps = 10/92 (10%)
Query: 5 ERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLL----------KT 54
E GG Y+++SR+LGAEFG++VGILF AN VAASM +G + + L
Sbjct: 133 ESGGAYFIISRNLGAEFGSAVGILFYLANTVAASMYIVGGVEVILMYLWPEMAIGGADAL 192
Query: 55 HGLKIVDNDVNDIRIVGAVALLVMCVICAIGM 86
H ++ + N++R+ G V LL+ +I A+G+
Sbjct: 193 HDTEMFGSLYNNLRLYGTVFLLIQALIVAMGV 224
Score = 64.1 bits (149), Expect = 1e-08
Identities = 42/153 (27%), Positives = 70/153 (45%), Gaps = 15/153 (9%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALR 210
FF + A+YFPAVTG+ G N+ GDL++P +IP GT+ A + Y+ + IL G
Sbjct: 379 FFMLMAIYFPAVTGIFTGTNMSGDLRDPQRSIPVGTIAATLTTSAIYYILAILFG----- 433
Query: 211 DASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXX 270
++T + L + G + N + L + G +
Sbjct: 434 ------GSITRSVL---RDKFGRSIGNTMVVAALSWPHPAVVTVGAFLSTFGAALQCLCS 484
Query: 271 VPRLIQALGVDRIYPGLIFFSKPYGRHGEPYRG 303
PRL+Q++ D + P L F++ ++ EP+ G
Sbjct: 485 APRLLQSIAKDDVIPILAPFAR-VTKNNEPFLG 516
Score = 44.4 bits (100), Expect = 0.012
Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 577 LSNGALSFRALSFNCKQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHK 636
++ G F S ++D WW+ +DGG+ +L+ Y++ + LRIFA++++
Sbjct: 760 VTKGITDFPEYSERLTGFIDIWWIVQDGGILMLIAYLLRQHKVWKGCTLRIFAVSEQDST 819
Query: 637 REFENKC-MESLLKKFRIEYTELTLV 661
+ + K ++ + RI+ EL +V
Sbjct: 820 KSEDMKAGLQKYIYMLRID-AELFIV 844
Score = 37.5 bits (83), Expect = 1.3
Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 695 EAELKSQYSKTSXXXXXXXXXXQHSTKAAIVIITLPLP---RKVSASLYMAWLEVLSRDL 751
E +K K + ++S + ++++ LP P R + YM +L+VL+ DL
Sbjct: 943 EGAMKLNIHKMNTSVRLNRVIRENSPDSQLILLNLPSPPRNRLAFNNSYMTYLDVLTEDL 1002
Query: 752 PPVLFVRGN 760
P VLF+ G+
Sbjct: 1003 PRVLFIGGS 1011
>UniRef50_A3IKP0 Cluster: Na-K-Cl cotransporter, putative; n=5;
Chroococcales|Rep: Na-K-Cl cotransporter, putative -
Cyanothece sp. CCY 0110
Length = 738
Score = 62.9 bits (146), Expect = 3e-08
Identities = 77/296 (26%), Positives = 113/296 (38%), Gaps = 53/296 (17%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG Y ++S+SLG E G SVG+ + A+AA+M GF + L H ++D V
Sbjct: 92 GGPYAMISKSLGLEIGGSVGVPLFVSQALAAAMYIFGFREGWLFLFPEHPPLLIDFTV-- 149
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFV 126
LV+ +I I + + Q + +L S+
Sbjct: 150 --------FLVIFIIAYISASFAFRVQYLVLILIILSLFSIFSSSLTWESN--------- 192
Query: 127 GINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGT 186
+ W +S F+VF FPA TG+ +G N+ G+L+N IP GT
Sbjct: 193 --------QTWQDWGDFSNISFWGVFAVF---FPATTGIMSGVNMSGELENSRQNIPIGT 241
Query: 187 LLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMS 246
L A+A+S Y VIL A + P L NNY I+ S
Sbjct: 242 LSAIALSTIIY---VILCWWVA----------------RAAPPQ---ELINNYTILVEKS 279
Query: 247 AWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYR 302
W + G PR++ AL D + P +K ++GEP R
Sbjct: 280 RWQFLVLMGLLAATFSASLSSLVGAPRILTALAKDGVIPWGNGLAK-LSKNGEPRR 334
>UniRef50_Q8NF23 Cluster: FLJ00379 protein; n=5; Euteleostomi|Rep:
FLJ00379 protein - Homo sapiens (Human)
Length = 487
Score = 62.1 bits (144), Expect = 5e-08
Identities = 40/142 (28%), Positives = 68/142 (47%), Gaps = 4/142 (2%)
Query: 320 SWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGS 379
SWG ++ + ++ L R H + + PQLL+L G P L+ +A+ L K G
Sbjct: 126 SWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGNPRGALPLLRLANQLKK-GG 184
Query: 380 FMIVADIT--DTALTKGERVSRQH-IGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASG 436
++ +T D + V Q+ V +++AF L +++GA L++ SG
Sbjct: 185 LYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDRAQVKAFVDLTLSPSVRQGAQHLLRISG 244
Query: 437 LGKLSPNILLIGFKKDWTNAEH 458
LG + PN L++GF D +H
Sbjct: 245 LGGMKPNTLVLGFYDDAPPQDH 266
>UniRef50_O44846 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 952
Score = 60.9 bits (141), Expect = 1e-07
Identities = 29/81 (35%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Query: 125 FVGINLQTIRENWLPNFR--YSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAI 182
+ G + T+ EN P + Y+ + DF +FA+ F VTG+ AGAN+ G+L P+V+I
Sbjct: 292 YTGWSFHTLGENMFPEYTMDYTTEKPTDFALMFAIIFSGVTGLMAGANMSGELARPSVSI 351
Query: 183 PKGTLLALAISVTSYFTMVIL 203
P+GT+ A+ +++ Y L
Sbjct: 352 PRGTVQAVFMTLFVYVMTAFL 372
Score = 60.5 bits (140), Expect = 2e-07
Identities = 39/135 (28%), Positives = 66/135 (48%), Gaps = 5/135 (3%)
Query: 319 VSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIG 378
VS GS ++ Y ++ L R H + + PQ+L+L P +L+D + L K G
Sbjct: 552 VSSGSISQALIYHQVRKYLLLLDVRKEHVKYWRPQILLLVSRPASACSLLDFVNDLKKSG 611
Query: 379 SFMIVADITDTALTKGERVSR-QHIGEQF---VKYRKLRAFYVLLQGLDLKRGANALMQA 434
++ V + + + V Q + + + Y KL+AF L +++ G LM+
Sbjct: 612 LYL-VGHVRKGEMDSSQVVDPLQQVFPYWLSLIDYLKLKAFVELTMSNNIRHGIQQLMRL 670
Query: 435 SGLGKLSPNILLIGF 449
SGLG + PN ++IGF
Sbjct: 671 SGLGAMKPNTVVIGF 685
Score = 54.4 bits (125), Expect = 1e-05
Identities = 23/46 (50%), Positives = 33/46 (71%)
Query: 3 ASERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSL 48
A E GGVYY++SRSLG EFG ++G+LF AN + ++ GF ++L
Sbjct: 144 AVEGGGVYYMISRSLGPEFGGAIGVLFFVANVFSCALYISGFTEAL 189
>UniRef50_A7SLI2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 919
Score = 60.9 bits (141), Expect = 1e-07
Identities = 27/55 (49%), Positives = 39/55 (70%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSG 205
FF + A++FP+VTG+ AG+N GDLK+ +IPKGT+ A+A + Y T V+L G
Sbjct: 235 FFILLAIFFPSVTGIMAGSNRSGDLKDAQNSIPKGTIAAIATTSFVYLTSVLLFG 289
Score = 50.4 bits (115), Expect = 2e-04
Identities = 34/143 (23%), Positives = 62/143 (43%), Gaps = 6/143 (4%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLA----GTPLQRPALIDVAHMLTK 376
WG G + L H++++ PQ+L+L Q L+ +A L
Sbjct: 485 WGDGIRGLALSAARFSLLRLEEGPPHTKNWRPQILILCKLDESLQPQSRRLLSLASQLKH 544
Query: 377 IGSFMIVADITDTALTK--GERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQA 434
IV + + + S + + +K K++ F ++ ++K+G + L+Q
Sbjct: 545 GKGLSIVGSVLEGEYQNLVTDITSAKENLKVCMKEEKVKGFMKIVTSENVKQGISFLIQG 604
Query: 435 SGLGKLSPNILLIGFKKDWTNAE 457
SGLG L PN +L+ F ++W E
Sbjct: 605 SGLGGLDPNTVLLAFPENWRERE 627
Score = 44.8 bits (101), Expect = 0.009
Identities = 19/42 (45%), Positives = 28/42 (66%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSL 48
GG Y+++SR+LG EFG +VG+LF A+SM +G + L
Sbjct: 66 GGSYFMISRALGPEFGGAVGLLFYLGTTFASSMYILGAIEIL 107
Score = 41.5 bits (93), Expect = 0.082
Identities = 18/60 (30%), Positives = 32/60 (53%)
Query: 595 VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIE 654
VD WW+ DGG+ IL+ +++ + + LRIF + + + K +E+ + RIE
Sbjct: 666 VDVWWIVHDGGMMILILFLLRQHKVWKRCKLRIFTVAQLEDNSIQMKKDLETFMYHLRIE 725
>UniRef50_Q9N5M5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 977
Score = 58.8 bits (136), Expect = 5e-07
Identities = 47/164 (28%), Positives = 72/164 (43%), Gaps = 16/164 (9%)
Query: 139 PNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYF 198
P++ Y+E + F + V+FP+ TG+ AG+N G+L++ A +IP GTL A S Y
Sbjct: 286 PSYIYAESVTN-FMILVGVFFPSATGIMAGSNRSGNLRDAAKSIPLGTLAAQNFSSFIYL 344
Query: 199 TMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMSAWGPFIYAGCWX 258
V+L G +V+ + + G I ++ + I GC+
Sbjct: 345 LGVVLFG--------ASVSEM------FIRDKYGRSAMGKLIISEISWPFPQVILFGCFM 390
Query: 259 XXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSKPYGRHGEPYR 302
PRL+QA+ D + P L F K R GEP R
Sbjct: 391 STAGAGMQSLTGAPRLLQAIAADDVLPFLKPFRKMDSR-GEPIR 433
Score = 58.0 bits (134), Expect = 9e-07
Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YY++SR+LG E G +VGILF +AASM G + L + K+ D+ ++
Sbjct: 66 GGPYYMISRNLGPELGGAVGILFYLGTTIAASMYITGAIEILLLYIYPQA-KLFDDIYHN 124
Query: 67 IRIVGAVALLVMCVICAIGM 86
R++G V LL++ +I G+
Sbjct: 125 FRVLGTVLLLILGLIVMAGV 144
Score = 43.2 bits (97), Expect = 0.027
Identities = 21/74 (28%), Positives = 35/74 (47%)
Query: 581 ALSFRALSFNCKQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFE 640
A F A ++D WW+ DGGL +LLP+++ + +R+FAI + +
Sbjct: 706 AEKFPANGTKVSGFIDVWWVVHDGGLLMLLPFLLRQHKTWKNTTVRLFAIAQMEDNNVQM 765
Query: 641 NKCMESLLKKFRIE 654
+E L RI+
Sbjct: 766 KTDLEKFLYHLRID 779
>UniRef50_Q6MD03 Cluster: Putative bumetanide-sensitive Na-K-Cl;
n=1; Candidatus Protochlamydia amoebophila UWE25|Rep:
Putative bumetanide-sensitive Na-K-Cl - Protochlamydia
amoebophila (strain UWE25)
Length = 764
Score = 58.4 bits (135), Expect = 7e-07
Identities = 42/150 (28%), Positives = 73/150 (48%), Gaps = 24/150 (16%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALR 210
F+++FA++FPA+TG+++ A++ GDLK+P+ ++P GT+ A+ +T+Y VI G+
Sbjct: 206 FWAIFAIFFPALTGIESSASLSGDLKDPSRSLPLGTITAV---LTAY---VIYIGISLFL 259
Query: 211 DASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXX 270
+ L L ++Q ++ + I G W
Sbjct: 260 FEMVPLDRLVMDPL----------------VIQHVAKFESLIILGIWGATLSSAIGGLLG 303
Query: 271 VPRLIQALGVDRIYPGLIFFSKPYGRHGEP 300
PR +QAL D I P + F++ YG + EP
Sbjct: 304 APRTLQALAEDGIVPRI--FAREYGPYCEP 331
Score = 45.2 bits (102), Expect = 0.007
Identities = 18/46 (39%), Positives = 29/46 (63%)
Query: 6 RGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHL 51
+GG YY++SR+LG E G+S+GI +++ S +GF +S L
Sbjct: 91 KGGAYYIISRALGLEVGSSIGIPLFLKQSISVSFCIVGFTESFQSL 136
Score = 41.5 bits (93), Expect = 0.082
Identities = 30/135 (22%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Query: 317 IDVSWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTP-LQRPALIDVAHMLT 375
I+ +W G + + I L++ + SRS+ P LV G P L L+ ++ +
Sbjct: 433 INTAWDDIRYGIFMFFSRAVIYRLANEMPSSRSWRPNFLVFTGKPSLVSDQLLSFSNAIA 492
Query: 376 KIGSFMIVADITDTALTKGERVSR--QHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQ 433
F+ +A ++++ Q I + +K+ ++A L Q + G ++
Sbjct: 493 HSKGFLTMASFFSPEQASQAQITQLDQRI-KTLLKHHDIQALVTLHQAKSVSSGMKQMIA 551
Query: 434 ASGLGKLSPNILLIG 448
G+G L+PN ++ G
Sbjct: 552 HYGIGPLTPNTIVCG 566
>UniRef50_A7Q1C8 Cluster: Chromosome chr10 scaffold_43, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr10 scaffold_43, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 1005
Score = 57.6 bits (133), Expect = 1e-06
Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 26/199 (13%)
Query: 114 GPSSDVERAKGFVGINLQTIRENWLPNFRYSEGR---------EHDFFSVFAVYFPAVTG 164
GP + G G++L+++++NW +++ + +F ++ ++FPAVTG
Sbjct: 333 GPMEKAIQIIGVTGLSLKSLKDNWSSSYQNTNNAGIPDPDGAVSWNFNALVGLFFPAVTG 392
Query: 165 VQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAAL 224
+ AG+N L++ +IP GTL A + Y V+L G A R+ L T +
Sbjct: 393 IMAGSNRSASLRDTQRSIPVGTLAATLSTSAMYLFSVLLFGSLATRE------KLLTDSF 446
Query: 225 ESCKPHCGYGLHNNYAIMQLMSAW--GPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDR 282
+ +G + ++ AW IY G PRL+ A+ D
Sbjct: 447 K-------FGFVISGVLLTATIAWPLPAIIYIGIILSTLGAALQSLTGAPRLLAAIANDD 499
Query: 283 IYPGLIFFSKPYGRHGEPY 301
I P L +F G EP+
Sbjct: 500 ILPVLHYFRVAEG--SEPH 516
Score = 51.6 bits (118), Expect = 8e-05
Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 10/89 (11%)
Query: 3 ASERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIG----FCDSL--NHLLKTHG 56
A + GG YYL+ R+LG E G S+G+ F NAVA S+ +G F D+L + +G
Sbjct: 69 AMKGGGPYYLIGRALGPEVGVSIGLCFFLGNAVAGSLYVLGAVETFLDALPGAGIFGVNG 128
Query: 57 ----LKIVDNDVNDIRIVGAVALLVMCVI 81
+ + +++D+++ G V +++C I
Sbjct: 129 TEAAVAVPSPNLHDLQVYGIVVTIILCFI 157
Score = 39.9 bits (89), Expect = 0.25
Identities = 36/174 (20%), Positives = 70/174 (40%), Gaps = 13/174 (7%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLA--------GTPLQRPALIDVAH 372
WG + +Q + + L H +++ P L+ P P L D A+
Sbjct: 622 WGDGFKSAYFQLALRSLRSLGASQVHPKNWYPIPLIFCRPWGKLPENVPCH-PKLADFAN 680
Query: 373 MLTKIGSFM-IVADITDTALTKGERVSRQHIGE--QFVKYRKLRAFYVLLQGLDLKRGAN 429
+ K G M I I D + ++ + ++ Y++ ++ + G
Sbjct: 681 CMKKKGRGMSIFVSILDGDYHECAEDAKTACRQLSTYIDYKRCEGVAEIVVAPSMSDGFR 740
Query: 430 ALMQASGLGKLSPNILLIGFKKDWTNAEHKQI-SDYYGVIQDAFDLKLAVTILR 482
++Q GLG L PNI+++ + + W +I + + G+I D AV I++
Sbjct: 741 GIVQTMGLGNLKPNIVVMRYPEIWRRENLIEIPATFVGIINDCIVANKAVVIVK 794
>UniRef50_A6R3M7 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 752
Score = 57.6 bits (133), Expect = 1e-06
Identities = 50/175 (28%), Positives = 78/175 (44%), Gaps = 19/175 (10%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG YYL+SRSLG EFG S+GI+F + MN +G +N L+++ G V +
Sbjct: 169 GGAYYLISRSLGPEFGGSIGIVFYIGFVLNTGMNAVGL---VNCLIQSFG--SVSGKWSQ 223
Query: 67 IRIVG-------AVALLVMCV-ICAIGMDWETKAQNFLXXXXXXXXXXXXXGAL-IGPSS 117
+ G A ++ +C IC G ++A N L AL + P
Sbjct: 224 FLLEGFGWTYLWATIVMTLCTGICLAGSSIFSRASNGLLVILLVSTFSIPFSALMMEPFK 283
Query: 118 DVERAKGFVGINLQTIRENWLPNF-RYSEGRE-H---DFFSVFAVYFPAVTGVQA 167
+ F G++ +T +N P + + G + H F +F + FPA G+ A
Sbjct: 284 NETLGIEFTGLSSKTFLDNLFPRLTKGAAGSQIHGRVTFQDLFGILFPATGGIFA 338
>UniRef50_UPI00015B4A73 Cluster: PREDICTED: similar to
potassium/chloride symporter, putative; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
potassium/chloride symporter, putative - Nasonia
vitripennis
Length = 1141
Score = 57.2 bits (132), Expect = 2e-06
Identities = 44/152 (28%), Positives = 66/152 (43%), Gaps = 15/152 (9%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALR 210
F + ++FP+VTG+ AG+N GDL + +IP GT+ A+ + T Y + V+L
Sbjct: 445 FTILIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTICAILTTSTVYLSCVLL------- 497
Query: 211 DASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXX 270
+G V NL + G + + + I G +
Sbjct: 498 -FAGTVDNLL------LRDKFGQSIGGRLVVANIAWPNEWVILVGSFLSTLGAGLQSLTG 550
Query: 271 VPRLIQALGVDRIYPGLIFFSKPYGRHGEPYR 302
PRL+QA+ D I P L F+K R GEP R
Sbjct: 551 APRLLQAIAKDSIIPFLAPFAKSSSR-GEPTR 581
Score = 52.0 bits (119), Expect = 6e-05
Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 6/91 (6%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCD-SLNHL---LKTHGLKIVDN 62
GG Y+++SRSLG EFG +VG+LF +AA+M IG + L ++ L G D
Sbjct: 222 GGSYFMISRSLGPEFGGAVGMLFYTGTTLAAAMYIIGAVEIVLTYMAPSLSIFGDFTKDP 281
Query: 63 DV--NDIRIVGAVALLVMCVICAIGMDWETK 91
+ N+ R+ G L+VM I IG+ + K
Sbjct: 282 SIMYNNFRVYGTCLLVVMGTIVFIGVKFVNK 312
Score = 51.2 bits (117), Expect = 1e-04
Identities = 33/143 (23%), Positives = 63/143 (44%), Gaps = 6/143 (4%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAG-----TPLQRPALIDVAHMLT 375
WG G + L H++++ PQ+L+LA P R V+ +
Sbjct: 686 WGDGIRGLALSAARYSLLRLEEGPPHTKNWRPQILILAKLTDDLVPKYRKMFAFVSQLKA 745
Query: 376 KIGSFMIVADIT-DTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQA 434
G + V IT D G+ + + + ++ K++ F +L ++ G ++L+Q
Sbjct: 746 SKGLTIAVGCITGDFTRRSGDAAAAKQALRRTMEEEKVKGFVDVLVAQNVIDGLSSLVQM 805
Query: 435 SGLGKLSPNILLIGFKKDWTNAE 457
+GLG + PN +++G+ W E
Sbjct: 806 TGLGGMKPNCVILGWPYSWRQTE 828
Score = 38.3 bits (85), Expect = 0.77
Identities = 16/60 (26%), Positives = 30/60 (50%)
Query: 595 VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIE 654
+ WW+ DGGL +LLP+++ + ++IF + + + K ++ L RIE
Sbjct: 870 IHVWWIVHDGGLLMLLPFLLKQHRTWKNCKMKIFTVAQMEDNSIQMKKDLKKFLYDLRIE 929
>UniRef50_UPI00015556EE Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 576
Score = 57.2 bits (132), Expect = 2e-06
Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 2/131 (1%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
WG + + ++ L R H + + PQ+L+L P ALI + L K G +
Sbjct: 264 WGHVNQALIFHQVRKYLLLLDTRKDHVKFWRPQVLLLVRNPRGSLALIHFVNHLKKSGLY 323
Query: 381 MIV-ADITDT-ALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQASGLG 438
++ ++ D +L ++++ Q V+ +++AF L ++ GA L+ SGLG
Sbjct: 324 LLGHVELQDLDSLPSDPLLAQEDSWLQLVEDLQIKAFVALTLASSVRLGAQQLLLTSGLG 383
Query: 439 KLSPNILLIGF 449
+ PN L++GF
Sbjct: 384 GMRPNTLILGF 394
Score = 38.3 bits (85), Expect = 0.77
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 12 LVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSL 48
++SR+LG EFGASVG+ F AN ++ +G +++
Sbjct: 16 MISRALGPEFGASVGLFFFLANGGGCALYVLGLVEAI 52
>UniRef50_A2DFI6 Cluster: Amino acid permease family protein; n=9;
Trichomonas vaginalis G3|Rep: Amino acid permease family
protein - Trichomonas vaginalis G3
Length = 833
Score = 56.4 bits (130), Expect = 3e-06
Identities = 46/198 (23%), Positives = 83/198 (41%), Gaps = 12/198 (6%)
Query: 8 GVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVNDI 67
G++Y++SR++G + G I + + A+ IG+ +S+ + + ++ NDI
Sbjct: 153 GIHYVISRTIGPDLGRCFTIFLDLSTCLGAASAIIGYSESIISMYEPKFF--TKSERNDI 210
Query: 68 RIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKGFVG 127
R++ A++++++ V A + + F G + + E GF
Sbjct: 211 RVI-AMSIMLISVPLARFFPYSLR---FTTTTHLIGIFGFILGCFVRKTGSTE---GFNR 263
Query: 128 INLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTL 187
N T + N + +SE F S P T + G G LK P IPKG
Sbjct: 264 PNFTTFKSN---TWSHSEMTVLKFMSYIYTVTPGFTALTGGFAYTGRLKRPQKMIPKGLW 320
Query: 188 LALAISVTSYFTMVILSG 205
A +SV + ++L G
Sbjct: 321 WAFGLSVIFWHVTILLIG 338
Score = 44.8 bits (101), Expect = 0.009
Identities = 45/178 (25%), Positives = 75/178 (42%), Gaps = 17/178 (9%)
Query: 589 FNCKQYVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLL 648
F+ +VD +WL +DGGL +L+ +++A K KL + A E + M L
Sbjct: 668 FHESSFVDVYWLADDGGLTLLVGFLMANY-LKKKLRVLTIAYKANGDTAEKSKERMSRLC 726
Query: 649 KKFRIEYTELTLVRGIGDAPPESSWKMFNNIINDFKSEEKTDILTSEAELKSQYSKTSXX 708
++FRI + + + P + +N E T + K
Sbjct: 727 ERFRINAEVIGIEIDENSSTPST--------VNKNYWEHLTRKFPYDPVFK-------RF 771
Query: 709 XXXXXXXXQHSTKAAIVIITLPL-PRKVSASLYMAWLEVLSRDLPPVLFVRGNDSCVL 765
++S KAA++I TL + P +S +Y+ L+++S FVRGN VL
Sbjct: 772 ILFADVIREYSNKAALIICTLFIPPTDMSNIMYLDLLKLISHIPTSFAFVRGNGHSVL 829
>UniRef50_Q4T7I7 Cluster: Chromosome undetermined SCAF8089, whole
genome shotgun sequence; n=5; Chordata|Rep: Chromosome
undetermined SCAF8089, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1211
Score = 54.0 bits (124), Expect = 1e-05
Identities = 48/151 (31%), Positives = 71/151 (47%), Gaps = 17/151 (11%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALR 210
F + ++FP+VTG+ AG+N GDLK+ +IP GT+LA+ + Y + V+L GA
Sbjct: 502 FTLLVGIFFPSVTGIMAGSNRSGDLKDAQRSIPIGTILAILTTSIVYLSSVVL--FGACI 559
Query: 211 DASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXX 270
D G V L +S K + G + S W I G +
Sbjct: 560 D--GVV--LRDKFGDSVKGNLVVG------TLAWPSPW--VIVVGSFFSTCGAGLQSLTG 607
Query: 271 VPRLIQALGVDRIYPGLIFFSKPYGR-HGEP 300
PRL+QA+ D + P L F +G+ +GEP
Sbjct: 608 APRLLQAIAKDNVIPFLRVFG--HGKANGEP 636
Score = 50.8 bits (116), Expect = 1e-04
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGL----KIVDN 62
GG Y+++SRSLG EFG +VG+ F A +M +G + L + K +
Sbjct: 236 GGSYFMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGAIEILLMYIAPKAAIFEPKHPEG 295
Query: 63 D----VNDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALI 113
+ +N++R+ G++ LL+M ++ +G+ + K + GAL+
Sbjct: 296 EGAAMLNNMRVYGSICLLLMSLLVFVGVKYVNKLASIFLACVIISIVSIYAGALV 350
Score = 48.8 bits (111), Expect = 5e-04
Identities = 32/146 (21%), Positives = 62/146 (42%), Gaps = 6/146 (4%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLA----GTPLQRPALIDVAHMLTK 376
WG G + L H++++ PQLLVL ++ P L+ A L
Sbjct: 743 WGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDAHVKSPRLLTFASQLKA 802
Query: 377 IGSFMIVADITDTALTK--GERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQA 434
IV + + GE ++ + + + +++ F + + G + ++Q+
Sbjct: 803 GKGLTIVGTVVSGNFLQSYGEALAAEQTLKHLMDKERVKGFCQCIVAQKPREGISHMIQS 862
Query: 435 SGLGKLSPNILLIGFKKDWTNAEHKQ 460
SGLG + PN +++G+ W +E Q
Sbjct: 863 SGLGGMKPNTVVMGWPHAWRQSEDPQ 888
Score = 35.9 bits (79), Expect = 4.1
Identities = 10/21 (47%), Positives = 17/21 (80%)
Query: 594 YVDAWWLYEDGGLNILLPYII 614
Y+D WW+ DGG+ +LLP+++
Sbjct: 927 YIDVWWIVHDGGMLMLLPFLL 947
>UniRef50_UPI0000F1E57D Cluster: PREDICTED: hypothetical protein,
partial; n=1; Danio rerio|Rep: PREDICTED: hypothetical
protein, partial - Danio rerio
Length = 649
Score = 53.2 bits (122), Expect = 3e-05
Identities = 23/55 (41%), Positives = 36/55 (65%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSG 205
F + +YFP+VTG+ AG+N GDL++ +IP GT+LA+ + Y + V+L G
Sbjct: 526 FTMLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPIGTILAITTTSIIYMSSVVLFG 580
Score = 44.8 bits (101), Expect = 0.009
Identities = 20/42 (47%), Positives = 26/42 (61%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSL 48
GG YY++SRSLG EFG +VGI F A +M +G + L
Sbjct: 284 GGSYYMISRSLGPEFGGAVGICFYLGTTYAGAMYILGCIEIL 325
Score = 44.8 bits (101), Expect = 0.009
Identities = 20/42 (47%), Positives = 26/42 (61%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSL 48
GG YY++SRSLG EFG +VGI F A +M +G + L
Sbjct: 356 GGSYYMISRSLGPEFGGAVGICFYLGTTYAGAMYILGCIEIL 397
>UniRef50_Q4T2D9 Cluster: Chromosome undetermined SCAF10292, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10292,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 801
Score = 52.8 bits (121), Expect = 3e-05
Identities = 20/46 (43%), Positives = 34/46 (73%)
Query: 3 ASERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSL 48
A + GG YY++SR+LG EFG S+GI+F FAN ++++ +G +++
Sbjct: 83 ALDAGGAYYMISRALGPEFGGSIGIMFFFANVCSSALYILGVVEAI 128
Score = 46.4 bits (105), Expect = 0.003
Identities = 30/129 (23%), Positives = 54/129 (41%), Gaps = 22/129 (17%)
Query: 173 GDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCG 232
GDLKNP+ +IP+GT+ A+ I+ +Y + +L A SC H
Sbjct: 362 GDLKNPSYSIPRGTMAAVIITFITYNLLALL-------------------AAWSCDRHL- 401
Query: 233 YGLHNNYAIMQLMSAWGPFIYAGCWXXXXXXXXXXXXXVPRLIQALGVDRIYPGLIFFSK 292
L +Y + ++ W P + G + R++ AL D ++ G++ ++
Sbjct: 402 --LQRDYGFLGDVNVWPPLVKVGIYSSSLSAAMSNLIGASRILYALSKDNLFDGVLALTR 459
Query: 293 PYGRHGEPY 301
G P+
Sbjct: 460 KTSHGGNPW 468
>UniRef50_Q9UHW9 Cluster: Solute carrier family 12 member 6; n=145;
Coelomata|Rep: Solute carrier family 12 member 6 - Homo
sapiens (Human)
Length = 1150
Score = 52.0 bits (119), Expect = 6e-05
Identities = 45/152 (29%), Positives = 66/152 (43%), Gaps = 19/152 (12%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALR 210
F + ++FP+VTG+ AG+N GDLK+ +IP GT+LA+ + Y + V+L G
Sbjct: 485 FTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG----- 539
Query: 211 DASGNVANLTTAALESCKPHCGYGLHNNYAIMQLM--SAWGPFIYAGCWXXXXXXXXXXX 268
A + L + G + N + L S W I G +
Sbjct: 540 ------ACIEGVVL---RDKFGDAVKGNLVVGTLSWPSPW--VIVIGSFFSTCGAGLQSL 588
Query: 269 XXVPRLIQALGVDRIYPGLIFFSKPYGRHGEP 300
PRL+QA+ D I P L F +GEP
Sbjct: 589 TGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEP 619
Score = 49.6 bits (113), Expect = 3e-04
Identities = 36/169 (21%), Positives = 72/169 (42%), Gaps = 7/169 (4%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVL----AGTPLQRPALIDVAHMLTK 376
WG G + L H++++ PQLLVL ++ P L+ A L
Sbjct: 726 WGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKA 785
Query: 377 IGSFMIVADIT--DTALTKGERVSRQHIGEQFVKYRKLRAFYVLLQGLDLKRGANALMQA 434
IV + + GE ++ + + ++ K++ F L+ L+ G + L+Q+
Sbjct: 786 GKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQS 845
Query: 435 SGLGKLSPNILLIGFKKDWTNAEHKQI-SDYYGVIQDAFDLKLAVTILR 482
GLG + N +++G+ W +E + + G ++ LA+ + +
Sbjct: 846 CGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAK 894
Score = 46.0 bits (104), Expect = 0.004
Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 8/93 (8%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDND--- 63
GG Y+++SR+LG EFG +VG+ F AA+M +G + + +D
Sbjct: 250 GGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALK 309
Query: 64 -----VNDIRIVGAVALLVMCVICAIGMDWETK 91
+N++R+ G L++M ++ IG+ + K
Sbjct: 310 ESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNK 342
Score = 43.6 bits (98), Expect = 0.020
Identities = 18/60 (30%), Positives = 32/60 (53%)
Query: 595 VDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRIE 654
+D WW+ DGG+ +LLP+++ + K +RIF + + + K + + L RIE
Sbjct: 911 IDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIE 970
>UniRef50_UPI0000E47BA3 Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 838
Score = 48.4 bits (110), Expect = 7e-04
Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 4/135 (2%)
Query: 321 WGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGSF 380
WG + + ++ L R H + + PQ+L+L P LI + + K G +
Sbjct: 442 WGYVGQALIFHQVRKYLLLLDIRKAHVKFWRPQILLLVSNPRASTQLIRFVNDMKKSGLY 501
Query: 381 MIVADITDTALTKG--ERVSRQHIGEQF-VKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
++ + L + + V +++ + V+ K++AF L ++ G LM+ SGL
Sbjct: 502 -VIGHVKTGLLDECPYDPVQQEYPAWLYLVESLKVKAFVELTLAPSVREGVMHLMRISGL 560
Query: 438 GKLSPNILLIGFKKD 452
G + PN +++GF D
Sbjct: 561 GGMKPNTVVMGFYDD 575
Score = 47.2 bits (107), Expect = 0.002
Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 3 ASERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDN 62
A E GG Y+++SR+LG E G S+G +F AN + + N F + L + G IV N
Sbjct: 75 AVEGGGAYFMISRALGPELGGSIGFIFYLANVFSCAFNCSAFTEILEDNFGSSG-SIVRN 133
Query: 63 DV 64
+
Sbjct: 134 GI 135
>UniRef50_UPI0000ECA8E1 Cluster: Solute carrier family 12 member 5
(Electroneutral potassium-chloride cotransporter 2)
(Erythroid K-Cl cotransporter 2) (Neuronal K-Cl
cotransporter) (hKCC2).; n=1; Gallus gallus|Rep: Solute
carrier family 12 member 5 (Electroneutral
potassium-chloride cotransporter 2) (Erythroid K-Cl
cotransporter 2) (Neuronal K-Cl cotransporter) (hKCC2).
- Gallus gallus
Length = 1027
Score = 46.4 bits (105), Expect = 0.003
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 8/93 (8%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCD-SLNHLLKTHGL-KIVDND- 63
GG YY++SRSLG EFG +VG+ F A +M +G + L ++ + K D
Sbjct: 145 GGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYIFPAMAIFKAEDASG 204
Query: 64 -----VNDIRIVGAVALLVMCVICAIGMDWETK 91
+N++R+ G L M + +G+ + K
Sbjct: 205 EAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNK 237
Score = 41.5 bits (93), Expect = 0.082
Identities = 17/60 (28%), Positives = 30/60 (50%)
Query: 594 YVDAWWLYEDGGLNILLPYIIARRGYKHKLPLRIFAITKEQHKREFENKCMESLLKKFRI 653
++D WW+ DGG+ +LLP+++ K +RIF + + K + + L RI
Sbjct: 740 HIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRI 799
Score = 39.1 bits (87), Expect = 0.44
Identities = 19/79 (24%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 405 QFVKYRKLRAFYVLLQGLDLKRGANALMQASGLGKLSPNILLIGFKKDWTNAE-HKQISD 463
+ ++ K++ F ++ +L+ G + L+Q+SGLG L N +L+G+ + W E H+ +
Sbjct: 646 RLMEAEKVKGFCQVVISSNLRDGMSHLIQSSGLGGLQHNTVLVGWPRSWRQKEDHQTWRN 705
Query: 464 YYGVIQDAFDLKLAVTILR 482
+ ++++ LA+ + +
Sbjct: 706 FIELVRETTAGHLALLVAK 724
>UniRef50_Q7PN04 Cluster: ENSANGP00000004794; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000004794 - Anopheles gambiae
str. PEST
Length = 104
Score = 43.6 bits (98), Expect = 0.020
Identities = 19/47 (40%), Positives = 30/47 (63%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSY 197
F + ++FP+VTG+ AG+N GDL + +IP GT+ A+ + T Y
Sbjct: 57 FTILIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTIGAIVTTSTVY 103
>UniRef50_P39282 Cluster: Inner membrane transporter yjeM; n=36;
Bacteria|Rep: Inner membrane transporter yjeM -
Escherichia coli (strain K12)
Length = 500
Score = 40.3 bits (90), Expect = 0.19
Identities = 56/257 (21%), Positives = 95/257 (36%), Gaps = 19/257 (7%)
Query: 2 YASERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNT-----IGFCDSLNHLLKTHG 56
Y E GG+Y ++ S+G F A +G F++ + ++T + F L T
Sbjct: 64 YRKEEGGIYSWMNNSVGPRF-AFIGTFMWFSSYIIWMVSTSAKVWVPFSTFLYGSDMTQH 122
Query: 57 LKIVDNDVNDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPS 116
+I + ++VG +A+ M ++ + K L+ S
Sbjct: 123 WRIAG--LEPTQVVGLLAVAWMILVTVVASKGINKIARITAVGGIAVMCLNLVLLLV--S 178
Query: 117 SDVERAKGFVGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLK 176
+ G G Q I PN Y G F VFA++ A G++A + +
Sbjct: 179 ITILLLNG--GHFAQDINFLASPNPGYQSGLAMLSFVVFAIF--AYGGIEAVGGLVDKTE 234
Query: 177 NPAVAIPKGTLLALAISVTSYFTMVILSGMG-----ALRDASGNVANLTTAALESCKPHC 231
NP KG + A + Y + L G+ L + S N+ N+T ++S
Sbjct: 235 NPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGSVNLGNITYVLMKSLGMTL 294
Query: 232 GYGLHNNYAIMQLMSAW 248
G LH + + W
Sbjct: 295 GNALHLSPEASLSLGVW 311
>UniRef50_UPI00004984DC Cluster: amino acid transporter; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: amino acid
transporter - Entamoeba histolytica HM-1:IMSS
Length = 476
Score = 38.7 bits (86), Expect = 0.58
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 136 NWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVT 195
NW Y DF + F+V F + GV+ AN+ ++KNP IP L L + +T
Sbjct: 178 NWRNLSTYLPYNHIDFSTFFSVIFWNLNGVENAANVIEEVKNPTRNIPLS--LFLLVVLT 235
Query: 196 SYFTMV-ILSGMG 207
S+ T +++G+G
Sbjct: 236 SFSTATPLMAGVG 248
>UniRef50_A3W042 Cluster: Amino acid transporter; n=1; Roseovarius
sp. 217|Rep: Amino acid transporter - Roseovarius sp.
217
Length = 419
Score = 38.3 bits (85), Expect = 0.77
Identities = 19/61 (31%), Positives = 30/61 (49%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILSGMGALR 210
F VF + F A TG + AN+ D NP +P L+ ++V Y + +++G L
Sbjct: 187 FGQVFMMIFFAFTGWELAANLSADFHNPRRDVPIAIGLSFCVAVLLYVVLAVIAGSLGLS 246
Query: 211 D 211
D
Sbjct: 247 D 247
>UniRef50_Q4RZ04 Cluster: Chromosome 16 SCAF14974, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 16 SCAF14974, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 624
Score = 37.9 bits (84), Expect = 1.0
Identities = 28/129 (21%), Positives = 54/129 (41%), Gaps = 2/129 (1%)
Query: 320 SWGSSTEGQRYQDTVSFITELSHRVTHSRSYNPQLLVLAGTPLQRPALIDVAHMLTKIGS 379
SWG ++ + ++ L R H + + PQ+L++ P LI + + K G
Sbjct: 167 SWGYISQALIFHQVRKYLLMLDVRKDHVKFWRPQILLMVSNPRSSVGLITFINDIKKSGL 226
Query: 380 FMI-VADITDTALTKGERVSRQHIG-EQFVKYRKLRAFYVLLQGLDLKRGANALMQASGL 437
+++ + D + + Q+ V + ++AF L ++ G L+ SGL
Sbjct: 227 YVLGHVQLGDLNTLPSDPLQSQYDSWLSLVDHLNIKAFVNLTLADSVRHGIQHLLFISGL 286
Query: 438 GKLSPNILL 446
G+ LL
Sbjct: 287 GQCHRRRLL 295
>UniRef50_P77400 Cluster: Inner membrane transport protein ybaT;
n=16; Enterobacteriaceae|Rep: Inner membrane transport
protein ybaT - Escherichia coli (strain K12)
Length = 430
Score = 37.9 bits (84), Expect = 1.0
Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 3/106 (2%)
Query: 151 FFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFT--MVILSGMGA 208
FFS + F A G AN +K+P V +P+ L+A+ ++ Y + +V+LS + A
Sbjct: 195 FFSCIGITFLAYAGFGMMANAADKVKDPQVIMPRAFLVAIGVTTLLYISLALVLLSDVSA 254
Query: 209 LRDASGNVANLTTAALESCKPHCGYGLHNNYAIMQLMSAWGPFIYA 254
L + A H GY + A++ SA ++A
Sbjct: 255 L-ELEKYADTAVAQAASPLLGHVGYVIVVIGALLATASAINANLFA 299
>UniRef50_Q6KYY4 Cluster: Amino acid permease; n=2;
Thermoplasmatales|Rep: Amino acid permease - Picrophilus
torridus
Length = 443
Score = 37.5 bits (83), Expect = 1.3
Identities = 44/197 (22%), Positives = 86/197 (43%), Gaps = 22/197 (11%)
Query: 6 RGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVN 65
+G + + G+E G +GIL F+ A A S +GF L+ +L HG N
Sbjct: 72 KGASFSYTYNAFGSELGFIIGILLYFSFATAISAIALGFGSYLSSVLLLHG--------N 123
Query: 66 DIRIVGAVALL-VMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKG 124
+ I+ A+ L+ ++ ++ IG+ + +FL A++ + G
Sbjct: 124 NYPIMFAILLIFILSIVNIIGIKKAARLDSFLVLIKLLILTVFIISAVL-----LAHFSG 178
Query: 125 FVGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPK 184
+ +N N+ + R S G + AV+F A +G Q+ + I +++ A +
Sbjct: 179 TLNLN------NFHGSARQS-GVLPVLSASIAVFF-AYSGFQSISTITSNVRGGASGAAR 230
Query: 185 GTLLALAISVTSYFTMV 201
+L++ IS+ Y ++
Sbjct: 231 AIVLSVVISMIFYILVI 247
>UniRef50_Q5C149 Cluster: SJCHGC05139 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC05139 protein - Schistosoma
japonicum (Blood fluke)
Length = 276
Score = 37.1 bits (82), Expect = 1.8
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 718 HSTKAAIVIITLPLPRKVSAS--LYMAWLEVLSRDLPPVLFVRGNDSCVLDA 767
HS+ + +VI+ +P P + S YM ++E L+ LP +L VRG V+ A
Sbjct: 222 HSSDSVLVIVNMPGPSRTLGSEYYYMDYIETLTDGLPRILLVRGTGREVITA 273
>UniRef50_A0YCV4 Cluster: Cationic amino acid transporter; n=1;
marine gamma proteobacterium HTCC2143|Rep: Cationic
amino acid transporter - marine gamma proteobacterium
HTCC2143
Length = 444
Score = 36.3 bits (80), Expect = 3.1
Identities = 19/58 (32%), Positives = 32/58 (55%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDV 64
GG Y+ V +LG G +VG + +AN + +++ +GF LL+ G+ I D+ V
Sbjct: 72 GGSYFWVKTALGRSAGFAVGWIGVYANTIVSALYALGFGAFFVALLQRLGVGISDDYV 129
>UniRef50_P53388 Cluster: Dicarboxylic amino acid permease; n=11;
Saccharomycetales|Rep: Dicarboxylic amino acid permease
- Saccharomyces cerevisiae (Baker's yeast)
Length = 608
Score = 36.3 bits (80), Expect = 3.1
Identities = 17/62 (27%), Positives = 30/62 (48%)
Query: 145 EGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVILS 204
+G+ F +VF + TG++ +C + +NP ++PK L + + Y V L
Sbjct: 280 KGKFVSFVAVFVYSLFSYTGIELTGIVCSEAENPRKSVPKAIKLTVYRIIVFYLCTVFLL 339
Query: 205 GM 206
GM
Sbjct: 340 GM 341
>UniRef50_Q89Q78 Cluster: Blr3252 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr3252 protein - Bradyrhizobium
japonicum
Length = 5685
Score = 35.5 bits (78), Expect = 5.4
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 10/80 (12%)
Query: 17 LGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVNDIRIVGAVALL 76
L G IL ++ANA A + +TIG SLNH +V+N+ + G+ +L
Sbjct: 917 LNGNLGVGGNILTSYANATADAGDTIGIAGSLNHF-------VVNNNTT-AWVAGSASLT 968
Query: 77 VMC--VICAIGMDWETKAQN 94
C C G W N
Sbjct: 969 ATCATAACGSGTGWSVGMDN 988
>UniRef50_A3DCD8 Cluster: Putative uncharacterized protein; n=1;
Clostridium thermocellum ATCC 27405|Rep: Putative
uncharacterized protein - Clostridium thermocellum
(strain ATCC 27405 / DSM 1237)
Length = 320
Score = 35.5 bits (78), Expect = 5.4
Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 3/54 (5%)
Query: 153 SVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYF-TMVILSG 205
S+F V F +GV AG+ + G K AV +P +++A A+++ Y MV+LSG
Sbjct: 219 SLFFVVFGLTSGVYAGSFLVGKKKTLAVLLP--SIVASAVTIVMYIGEMVLLSG 270
>UniRef50_Q875M6 Cluster: DIP5; n=2; Saccharomycetaceae|Rep: DIP5 -
Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 605
Score = 35.5 bits (78), Expect = 5.4
Identities = 19/63 (30%), Positives = 29/63 (46%)
Query: 144 SEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYFTMVIL 203
++GR F SVF + A G + + + KNP A+PK L + + Y + L
Sbjct: 276 AKGRFVSFASVFVLALFAYLGTELCGIVVSECKNPRKAVPKAIKLTMYRIIVFYLISIFL 335
Query: 204 SGM 206
GM
Sbjct: 336 LGM 338
>UniRef50_Q83CZ7 Cluster: Amino acid permease family protein; n=11;
Bacteria|Rep: Amino acid permease family protein -
Coxiella burnetii
Length = 437
Score = 35.1 bits (77), Expect = 7.1
Identities = 56/223 (25%), Positives = 88/223 (39%), Gaps = 28/223 (12%)
Query: 7 GGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDVND 66
GG + R L G + G +F A +A+ +GF L HLL G+ ++
Sbjct: 81 GGTHEYGYRYLHPALGFTAGWMFLCAKIASAATAALGFAGYLLHLL---GI----TSISM 133
Query: 67 IRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGP-SSDVERAKGF 125
I I ++A+L+ ++ + G+ A + L S + K F
Sbjct: 134 IPIAVSIAILLTLLVLS-GLKKSNLANLIIVSIILISLITFVLSGLPHLFSMGLPHFKPF 192
Query: 126 VGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKG 185
T + L NF Y+ A+ F A TG A + ++KNP IP+
Sbjct: 193 ----FPTAAPSGLRNFLYAT----------ALMFVAYTGYARIATLGEEVKNPKRFIPQA 238
Query: 186 TLLALAISVTSYFTMVILS----GMGALRDASGNVAN-LTTAA 223
+L L IS Y + +++ G L A+ N A L TAA
Sbjct: 239 IILTLIISAVLYIAVAVVAISIVGADHLSQAAQNRATPLETAA 281
>UniRef50_Q0TRW3 Cluster: Amino acid permease family protein; n=3;
Clostridium perfringens|Rep: Amino acid permease family
protein - Clostridium perfringens (strain ATCC 13124 /
NCTC 8237 / Type A)
Length = 489
Score = 35.1 bits (77), Expect = 7.1
Identities = 54/237 (22%), Positives = 88/237 (37%), Gaps = 20/237 (8%)
Query: 5 ERGGVYYLVSRSLGAEFGASVGILFAFANAVAASMNTIGFCDSLNHLLKTHGLKIVDNDV 64
+ GG+Y +++SLG ++ A VG F + D++
Sbjct: 66 KEGGIYSWINKSLGEKW-AFVGTWTYFIGILFYLQMVFSRIPVAASWAILGRNVFTDSNA 124
Query: 65 NDIRIVGAVALLVMCVICAIGMDWETKAQNFLXXXXXXXXXXXXXGALIGPSSDVERAKG 124
+ I+ V + M I IG+ +K +F A++G A
Sbjct: 125 YLLPILSIVICIAMTYIATIGVSKFSKLADFGGQFTLGATVIFILMAIVGYFMGTPSATE 184
Query: 125 FVGINLQTIRENWLPNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPK 184
F T+ +N +P+F S +FS F+ AV+G + +NP PK
Sbjct: 185 F------TV-QNVIPDFNVS------YFSTFSWLLFAVSGSEVAGTYIMQTENPKKTFPK 231
Query: 185 GTLLALAISVTSYFTMVILSGMGALRDASGNVANLTTAALESCKPHCGYGLHNNYAI 241
++A A+ SY IL + AS V L A ++ Y L NN+ I
Sbjct: 232 AMIIATALIAFSY----ILGSVAIQFIASPEV--LQKAGIQDAGYVVYYILANNFGI 282
>UniRef50_A7TMM7 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 497
Score = 35.1 bits (77), Expect = 7.1
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 626 RIFAITKEQHKREFENKCMESLLKKFRIEYTELTLVRGIGDAPPESSWKMFNNIINDFKS 685
R F + EQH ++FE + E LK F++ TE V A ESS + I + K+
Sbjct: 224 RQFKESLEQHLQKFELQITEMFLKPFQLFDTE--SVTNNNSALIESSKNNLSKYIENLKN 281
Query: 686 EEKTDILTSEAELKSQYSKT 705
+ +T E SQ S T
Sbjct: 282 YNENTAITKREETASQVSTT 301
>UniRef50_Q8ZYY0 Cluster: Amino acid permease; n=4; Pyrobaculum|Rep:
Amino acid permease - Pyrobaculum aerophilum
Length = 431
Score = 35.1 bits (77), Expect = 7.1
Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 139 PNFRYSEGREHDFFSVFAVYFPAVTGVQAGANICGDLKNPAVAIPKGTLLALAISVTSYF 198
P F +S F++ TG+ A + G+ + P V +P+ TLL +A+ T Y
Sbjct: 180 PFFNWSNVEGVSLLFAFSLLSRGFTGIDAIGQLAGEAREPLVQVPRATLLVVAMG-TFYG 238
Query: 199 TMVILSGMGAL 209
++ + M AL
Sbjct: 239 IGLMAAVMSAL 249
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.321 0.136 0.409
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 742,061,338
Number of Sequences: 1657284
Number of extensions: 27135008
Number of successful extensions: 59618
Number of sequences better than 10.0: 98
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 59138
Number of HSP's gapped (non-prelim): 317
length of query: 767
length of database: 575,637,011
effective HSP length: 107
effective length of query: 660
effective length of database: 398,307,623
effective search space: 262883031180
effective search space used: 262883031180
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 76 (34.7 bits)
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