Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001458-TA|BGIBMGA001458-PA|IPR002290|Serine/threonine
protein kinase, IPR000719|Protein kinase, IPR008271|Serine/threonine
protein kinase, active site, IPR011009|Protein kinase-like
(403 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q02750 Cluster: Dual specificity mitogen-activated prot... 545 e-153
UniRef50_Q99078 Cluster: Dual specificity protein kinase FUZ7; n... 305 1e-81
UniRef50_Q5KKP1 Cluster: MAP kinase kinase, putative; n=4; Treme... 300 4e-80
UniRef50_Q9Y7W8 Cluster: MAP kinase kinase; n=1; Yarrowia lipoly... 285 1e-75
UniRef50_Q6GX81 Cluster: Mitogen activated protein kinase kinase... 280 4e-74
UniRef50_Q0MQZ3 Cluster: STE7-like protein; n=14; Ascomycota|Rep... 277 5e-73
UniRef50_P10506 Cluster: Protein kinase byr1; n=1; Schizosacchar... 262 2e-68
UniRef50_Q13163 Cluster: Dual specificity mitogen-activated prot... 256 1e-66
UniRef50_Q96W50 Cluster: Protein kinase Pbs2p; n=14; Fungi/Metaz... 254 2e-66
UniRef50_P08018 Cluster: MAP kinase kinase PBS2; n=7; Saccharomy... 254 2e-66
UniRef50_Q6CEG1 Cluster: Yarrowia lipolytica chromosome B of str... 248 2e-64
UniRef50_Q4P4U9 Cluster: Putative uncharacterized protein; n=1; ... 243 8e-63
UniRef50_Q9S7U9 Cluster: Mitogen-activated protein kinase kinase... 241 2e-62
UniRef50_P33886 Cluster: Protein kinase wis1; n=1; Schizosacchar... 240 4e-62
UniRef50_Q876Z4 Cluster: Putative PBS2 like MAPK kinase; n=1; Ne... 231 2e-59
UniRef50_Q5KN75 Cluster: MAP kinase kinase, putative; n=1; Filob... 229 1e-58
UniRef50_Q9Y884 Cluster: MAP kinase kinase skh1/pek1; n=1; Schiz... 226 7e-58
UniRef50_Q5KGY3 Cluster: Mitogen-activated protein kinase kinase... 223 5e-57
UniRef50_Q75BS5 Cluster: ACR196Cp; n=2; Saccharomycetaceae|Rep: ... 222 1e-56
UniRef50_Q6BLD0 Cluster: Similar to ca|CA1623|CaSTE7 Candida alb... 220 5e-56
UniRef50_P32490 Cluster: MAP kinase kinase MKK1/SSP32; n=8; Sacc... 220 5e-56
UniRef50_A2RAN1 Cluster: Contig An18c0110, complete genome; n=19... 220 6e-56
UniRef50_A0CZB0 Cluster: Chromosome undetermined scaffold_32, wh... 219 1e-55
UniRef50_UPI000023D36E Cluster: hypothetical protein FG08691.1; ... 217 3e-55
UniRef50_Q9P8J0 Cluster: Map kinase kinase; n=1; Pneumocystis ca... 214 4e-54
UniRef50_Q6BTT8 Cluster: Similar to CA4577|CaMKK2 Candida albica... 213 9e-54
UniRef50_Q24D49 Cluster: Protein kinase domain containing protei... 212 1e-53
UniRef50_A6QXW3 Cluster: Putative uncharacterized protein; n=1; ... 212 1e-53
UniRef50_A1D1G2 Cluster: MAP kinase kinase (Pbs2), putative; n=8... 212 2e-53
UniRef50_P06784 Cluster: Serine/threonine-protein kinase STE7; n... 212 2e-53
UniRef50_Q6CET2 Cluster: Similar to sp|P32490 Saccharomyces cere... 211 2e-53
UniRef50_A1DYH9 Cluster: MAP kinase kinase PBS2 isoform B1; n=9;... 211 3e-53
UniRef50_O00885 Cluster: MAP kinase kinase protein DdMEK1; n=3; ... 210 5e-53
UniRef50_A7TL15 Cluster: Putative uncharacterized protein; n=1; ... 208 2e-52
UniRef50_A7TKP9 Cluster: Putative uncharacterized protein; n=1; ... 208 2e-52
UniRef50_UPI0000D55779 Cluster: PREDICTED: similar to mitogen ac... 206 6e-52
UniRef50_P46599 Cluster: Serine/threonine-protein kinase STE7 ho... 205 2e-51
UniRef50_Q01AJ5 Cluster: MAPKK; n=2; Ostreococcus|Rep: MAPKK - O... 203 7e-51
UniRef50_Q17FJ2 Cluster: Dual specificity mitogen-activated prot... 202 1e-50
UniRef50_A0CCZ2 Cluster: Chromosome undetermined scaffold_169, w... 197 4e-49
UniRef50_Q6FQU4 Cluster: Candida glabrata strain CBS138 chromoso... 197 4e-49
UniRef50_Q23977 Cluster: Dual specificity mitogen-activated prot... 196 1e-48
UniRef50_Q59T28 Cluster: Likely protein kinase; n=3; Saccharomyc... 195 2e-48
UniRef50_P45985 Cluster: Dual specificity mitogen-activated prot... 194 5e-48
UniRef50_Q07192 Cluster: Dual specificity mitogen-activated prot... 192 1e-47
UniRef50_UPI00015B4BE4 Cluster: PREDICTED: hypothetical protein;... 191 3e-47
UniRef50_O80396 Cluster: MAP kinase kinase 3; n=4; core eudicoty... 190 6e-47
UniRef50_UPI00003C01CC Cluster: PREDICTED: similar to mitogen-ac... 188 2e-46
UniRef50_A3FK65 Cluster: Mitogen-activated protein kinase kinase... 188 2e-46
UniRef50_Q4H379 Cluster: Mitogen-activated protein kinase kinase... 188 3e-46
UniRef50_Q9FX43 Cluster: MAP kinase, putative; n=11; core eudico... 186 1e-45
UniRef50_A0DZW8 Cluster: Chromosome undetermined scaffold_70, wh... 182 1e-44
UniRef50_A0BSN2 Cluster: Chromosome undetermined scaffold_125, w... 182 1e-44
UniRef50_Q86IX1 Cluster: Similar to Oryza sativa (Rice). 36I5.3;... 182 2e-44
UniRef50_Q2WBY4 Cluster: MAP kinase kinase; n=1; Platynereis dum... 176 7e-43
UniRef50_P46734 Cluster: Dual specificity mitogen-activated prot... 176 7e-43
UniRef50_Q23CK7 Cluster: Protein kinase domain containing protei... 176 1e-42
UniRef50_Q95YI9 Cluster: MAP kinase kinase SEK-1; n=2; Caenorhab... 175 2e-42
UniRef50_O14733 Cluster: Dual specificity mitogen-activated prot... 175 2e-42
UniRef50_Q2H575 Cluster: Putative uncharacterized protein; n=1; ... 175 2e-42
UniRef50_Q13188 Cluster: Serine/threonine-protein kinase 3; n=84... 173 7e-42
UniRef50_Q22553 Cluster: Germinal center kinase family protein 1... 172 2e-41
UniRef50_Q6C8H9 Cluster: Similar to tr|Q871H9 Neurospora crassa ... 172 2e-41
UniRef50_Q4Q1Z0 Cluster: Protein kinase, putative; n=5; Trypanos... 171 2e-41
UniRef50_A2EML4 Cluster: STE family protein kinase; n=1; Trichom... 170 5e-41
UniRef50_Q8T0S6 Cluster: Serine/threonine-protein kinase hippo; ... 167 3e-40
UniRef50_Q175W2 Cluster: Serine/threonine protein kinase; n=2; C... 165 1e-39
UniRef50_A0EIS6 Cluster: Chromosome undetermined scaffold_99, wh... 165 1e-39
UniRef50_UPI0000660B42 Cluster: Homolog of Homo sapiens "Serine/... 165 2e-39
UniRef50_Q8IGS1 Cluster: RE38276p; n=2; Drosophila melanogaster|... 165 2e-39
UniRef50_Q38B76 Cluster: Protein kinase, putative; n=1; Trypanos... 163 7e-39
UniRef50_O14305 Cluster: Serine/threonine-protein kinase sid1; n... 163 7e-39
UniRef50_UPI0000E47F28 Cluster: PREDICTED: similar to Map2k3 pro... 163 1e-38
UniRef50_O61122 Cluster: Severin kinase; n=2; Dictyostelium disc... 161 4e-38
UniRef50_Q20347 Cluster: MAP kinase kinase mkk-4; n=4; Rhabditid... 160 7e-38
UniRef50_Q9Y6E0 Cluster: Serine/threonine-protein kinase 24; n=1... 159 9e-38
UniRef50_A0EBN0 Cluster: Chromosome undetermined scaffold_88, wh... 159 2e-37
UniRef50_Q5KD75 Cluster: Putative uncharacterized protein; n=1; ... 157 4e-37
UniRef50_Q871H9 Cluster: Related to Ste20-like kinase Don3; n=2;... 157 5e-37
UniRef50_Q9UAH1 Cluster: JKK-1; n=2; Caenorhabditis|Rep: JKK-1 -... 157 6e-37
UniRef50_Q8NJX3 Cluster: Ste20-like kinase Don3; n=2; Ustilago m... 157 6e-37
UniRef50_A2R1E1 Cluster: Contig An13c0040, complete genome; n=4;... 156 1e-36
UniRef50_A2F5W2 Cluster: STE family protein kinase; n=2; Trichom... 155 1e-36
UniRef50_A1DC98 Cluster: Ste20-like serine/threonine protein kin... 155 2e-36
UniRef50_Q7Q155 Cluster: ENSANGP00000022332; n=6; Endopterygota|... 154 3e-36
UniRef50_Q4QEZ0 Cluster: Protein kinase, putative; n=3; Leishman... 154 3e-36
UniRef50_UPI00015551F0 Cluster: PREDICTED: similar to Serine/thr... 154 5e-36
UniRef50_Q5KDT4 Cluster: Serine/threonine protein kinase MST4, p... 153 8e-36
UniRef50_Q0UWD5 Cluster: Putative uncharacterized protein; n=2; ... 152 1e-35
UniRef50_O80397 Cluster: Mitogen-activated protein kinase kinase... 152 1e-35
UniRef50_Q21307 Cluster: Map kinase kinase or erk kinase protein... 152 2e-35
UniRef50_Q4DPN9 Cluster: Protein kinase, putative; n=3; Trypanos... 151 4e-35
UniRef50_O14047 Cluster: Serine/threonine-protein kinase ppk11; ... 151 4e-35
UniRef50_Q9LDN6 Cluster: MAP kinase; n=18; Magnoliophyta|Rep: MA... 150 6e-35
UniRef50_Q6C3K8 Cluster: Similar to DEHA0C16181g Debaryomyces ha... 149 2e-34
UniRef50_Q0V1V7 Cluster: Putative uncharacterized protein; n=1; ... 148 3e-34
UniRef50_UPI00006A0B9B Cluster: Mitogen-activated protein kinase... 146 7e-34
UniRef50_Q8MPS3 Cluster: Putative uncharacterized protein; n=3; ... 146 7e-34
UniRef50_O94804 Cluster: Serine/threonine-protein kinase 10; n=3... 146 7e-34
UniRef50_A7P1R5 Cluster: Chromosome chr19 scaffold_4, whole geno... 144 3e-33
UniRef50_Q55GC2 Cluster: Putative uncharacterized protein; n=1; ... 144 3e-33
UniRef50_Q0UBD3 Cluster: Putative uncharacterized protein; n=1; ... 143 8e-33
UniRef50_Q4Q2Z2 Cluster: Protein kinase, putative; n=6; Trypanos... 142 1e-32
UniRef50_O61125 Cluster: Kinase responsive to stress 1-like kina... 142 1e-32
UniRef50_Q9M8J5 Cluster: Putative MAP kinase; n=1; Arabidopsis t... 142 2e-32
UniRef50_Q55FS2 Cluster: Calpain-like cysteine protease; n=1; Di... 142 2e-32
UniRef50_Q0CAV5 Cluster: Serine/threonine-protein kinase 24; n=7... 141 3e-32
UniRef50_Q9LQA1 Cluster: F4N2.17; n=8; Magnoliophyta|Rep: F4N2.1... 140 5e-32
UniRef50_A0E889 Cluster: Chromosome undetermined scaffold_82, wh... 140 5e-32
UniRef50_Q22AD4 Cluster: Protein kinase domain containing protei... 140 8e-32
UniRef50_Q7QR27 Cluster: GLP_576_6939_8012; n=1; Giardia lamblia... 139 1e-31
UniRef50_A5BPZ0 Cluster: Putative uncharacterized protein; n=1; ... 139 1e-31
UniRef50_A7P2E2 Cluster: Chromosome chr1 scaffold_5, whole genom... 138 2e-31
UniRef50_Q54B33 Cluster: Putative uncharacterized protein pakE; ... 138 2e-31
UniRef50_A0EER6 Cluster: Chromosome undetermined scaffold_92, wh... 138 2e-31
UniRef50_Q9H2G2 Cluster: STE20-like serine/threonine-protein kin... 138 2e-31
UniRef50_O55092 Cluster: STE20-like serine/threonine-protein kin... 138 2e-31
UniRef50_Q22AY1 Cluster: Protein kinase domain containing protei... 138 3e-31
UniRef50_UPI0000F53448 Cluster: STE20-LIKE SERINE-THREONINE KINA... 137 6e-31
UniRef50_Q54XJ4 Cluster: Putative uncharacterized protein; n=1; ... 136 7e-31
UniRef50_A0C8K1 Cluster: Chromosome undetermined scaffold_158, w... 136 7e-31
UniRef50_Q6BP91 Cluster: Debaryomyces hansenii chromosome E of s... 136 7e-31
UniRef50_Q7SY52 Cluster: Zgc:63495; n=10; Euteleostomi|Rep: Zgc:... 136 1e-30
UniRef50_Q551J3 Cluster: Putative uncharacterized protein; n=2; ... 136 1e-30
UniRef50_A2QHV0 Cluster: Contig An04c0070, complete genome; n=4;... 136 1e-30
UniRef50_Q22A21 Cluster: Protein kinase domain containing protei... 135 2e-30
UniRef50_Q4P842 Cluster: Putative uncharacterized protein; n=1; ... 135 2e-30
UniRef50_A5DK74 Cluster: Putative uncharacterized protein; n=1; ... 135 2e-30
UniRef50_UPI0000D5577B Cluster: PREDICTED: similar to STE20-like... 134 3e-30
UniRef50_A6QQ50 Cluster: MAP4K1 protein; n=1; Bos taurus|Rep: MA... 134 3e-30
UniRef50_A2EWJ0 Cluster: STE family protein kinase; n=2; Trichom... 134 3e-30
UniRef50_A7P2X0 Cluster: Chromosome chr1 scaffold_5, whole genom... 134 4e-30
UniRef50_A5DHS1 Cluster: Putative uncharacterized protein; n=1; ... 134 4e-30
UniRef50_A5DH79 Cluster: Putative uncharacterized protein; n=1; ... 134 4e-30
UniRef50_UPI00004998B6 Cluster: cell division control protein 7;... 134 5e-30
UniRef50_Q54RV3 Cluster: Putative uncharacterized protein pakG; ... 134 5e-30
UniRef50_Q5AI03 Cluster: Likely protein kinase; n=2; Saccharomyc... 134 5e-30
UniRef50_UPI000065E60F Cluster: STE20-like serine/threonine-prot... 133 9e-30
UniRef50_Q6DDZ8 Cluster: MGC81192 protein; n=1; Xenopus laevis|R... 133 9e-30
UniRef50_Q6C2G1 Cluster: Yarrowia lipolytica chromosome F of str... 133 9e-30
UniRef50_Q92918 Cluster: Mitogen-activated protein kinase kinase... 132 1e-29
UniRef50_A0C9W0 Cluster: Chromosome undetermined scaffold_16, wh... 131 3e-29
UniRef50_Q4PC98 Cluster: Putative uncharacterized protein; n=1; ... 131 3e-29
UniRef50_A3LT13 Cluster: Predicted protein; n=1; Pichia stipitis... 131 3e-29
UniRef50_O22040 Cluster: Mitogen-activated protein kinase kinase... 131 3e-29
UniRef50_Q4S8I5 Cluster: Chromosome 2 SCAF14705, whole genome sh... 131 4e-29
UniRef50_Q9M269 Cluster: Serine/threonine-protein kinase-like pr... 131 4e-29
UniRef50_Q59SB5 Cluster: Likely protein kinase; n=4; Saccharomyc... 131 4e-29
UniRef50_UPI0001509E5E Cluster: Streptococcal surface antigen re... 130 5e-29
UniRef50_Q24C63 Cluster: Protein kinase domain containing protei... 130 5e-29
UniRef50_A2DLZ6 Cluster: AGC family protein kinase; n=1; Trichom... 130 5e-29
UniRef50_UPI0000E4894F Cluster: PREDICTED: hypothetical protein;... 130 6e-29
UniRef50_Q381A7 Cluster: Mitogen activated protein kinase, putat... 130 6e-29
UniRef50_Q5KHJ6 Cluster: MAP kinase kinase kinase, putative; n=2... 130 6e-29
UniRef50_A7RIM4 Cluster: Predicted protein; n=1; Nematostella ve... 130 8e-29
UniRef50_A3FQ10 Cluster: Protein kinase NPK2; n=2; Cryptosporidi... 130 8e-29
UniRef50_A2FCZ8 Cluster: CAMK family protein kinase; n=1; Tricho... 130 8e-29
UniRef50_A2E8U1 Cluster: AGC family protein kinase; n=1; Trichom... 130 8e-29
UniRef50_Q6BQI3 Cluster: Debaryomyces hansenii chromosome E of s... 130 8e-29
UniRef50_Q03497 Cluster: Serine/threonine-protein kinase STE20; ... 130 8e-29
UniRef50_Q8IVW4 Cluster: Cyclin-dependent kinase-like 3; n=36; M... 130 8e-29
UniRef50_UPI000059FEE9 Cluster: PREDICTED: similar to Mitogen-ac... 129 1e-28
UniRef50_Q7ZUA2 Cluster: Mitogen-activated protein kinase kinase... 129 1e-28
UniRef50_Q9LQM8 Cluster: F5D14.7 protein; n=2; Arabidopsis thali... 129 1e-28
UniRef50_Q0USU3 Cluster: Putative uncharacterized protein; n=1; ... 129 1e-28
UniRef50_Q92212 Cluster: Serine/threonine-protein kinase CST20; ... 129 1e-28
UniRef50_UPI0000498D8F Cluster: protein kinase; n=2; Entamoeba h... 128 2e-28
UniRef50_Q32NV8 Cluster: LOC443633 protein; n=6; Euteleostomi|Re... 128 2e-28
UniRef50_Q5BW36 Cluster: SJCHGC05877 protein; n=1; Schistosoma j... 128 2e-28
UniRef50_Q55CA6 Cluster: Putative uncharacterized protein; n=1; ... 128 2e-28
UniRef50_A6YTD4 Cluster: NPK1-like kinase; n=1; Cucumis melo|Rep... 128 3e-28
UniRef50_Q4QA98 Cluster: Mitogen-activated protein kinase; n=8; ... 128 3e-28
UniRef50_O42625 Cluster: MAPKK kinase; n=6; Pezizomycotina|Rep: ... 128 3e-28
UniRef50_Q8IVH8 Cluster: Mitogen-activated protein kinase kinase... 128 3e-28
UniRef50_UPI0000563837 Cluster: serine/threonine kinase; n=1; Gi... 128 3e-28
UniRef50_UPI0000498BDB Cluster: cell division control protein 7;... 128 3e-28
UniRef50_Q170F5 Cluster: P21-activated kinase, pak; n=2; Coeloma... 128 3e-28
UniRef50_Q7Z8J5 Cluster: MAP kinase kinase kinase; n=1; Yarrowia... 128 3e-28
UniRef50_Q75CM3 Cluster: ACL104Cp; n=1; Eremothecium gossypii|Re... 128 3e-28
UniRef50_UPI0000D9E73A Cluster: PREDICTED: serine/threonine kina... 127 4e-28
UniRef50_UPI0000D5575B Cluster: PREDICTED: similar to CG10951-PA... 127 4e-28
UniRef50_Q7QP54 Cluster: GLP_382_9339_8068; n=1; Giardia lamblia... 127 4e-28
UniRef50_A2FCS6 Cluster: STE family protein kinase; n=1; Trichom... 127 4e-28
UniRef50_Q9UKE5 Cluster: TRAF2 and NCK-interacting protein kinas... 127 4e-28
UniRef50_A2ACR7 Cluster: Cyclin-dependent kinase-like 3; n=10; E... 127 6e-28
UniRef50_Q01I65 Cluster: H0315A08.7 protein; n=8; Oryza sativa|R... 127 6e-28
UniRef50_Q9VC32 Cluster: CG10951-PA; n=2; Sophophora|Rep: CG1095... 127 6e-28
UniRef50_Q869T7 Cluster: Similar to Dictyostelium discoideum (Sl... 127 6e-28
UniRef50_Q55FT4 Cluster: Putative uncharacterized protein tsuA; ... 127 6e-28
UniRef50_O59790 Cluster: Serine/threonine-protein kinase ark1; n... 127 6e-28
UniRef50_Q5FZP2 Cluster: P21-activated kinase; n=1; Entamoeba hi... 126 8e-28
UniRef50_A0D0Y6 Cluster: Chromosome undetermined scaffold_33, wh... 126 8e-28
UniRef50_Q9Y4K4 Cluster: Mitogen-activated protein kinase kinase... 126 8e-28
UniRef50_Q5MAI5 Cluster: Cyclin-dependent kinase-like 4; n=18; M... 126 8e-28
UniRef50_UPI00006CBCB4 Cluster: Protein kinase domain containing... 126 1e-27
UniRef50_UPI000069E043 Cluster: UPI000069E043 related cluster; n... 126 1e-27
UniRef50_Q556S2 Cluster: Putative uncharacterized protein; n=2; ... 126 1e-27
UniRef50_A5DCL7 Cluster: Putative uncharacterized protein; n=1; ... 126 1e-27
UniRef50_Q6CVA2 Cluster: Serine/threonine-protein kinase STE20; ... 126 1e-27
UniRef50_Q54XL6 Cluster: Putative uncharacterized protein; n=1; ... 125 2e-27
UniRef50_Q4DSQ1 Cluster: Protein kinase, putative; n=2; Trypanos... 125 2e-27
UniRef50_A0BYR7 Cluster: Chromosome undetermined scaffold_137, w... 125 2e-27
UniRef50_Q751V1 Cluster: AFR724Cp; n=1; Eremothecium gossypii|Re... 125 2e-27
UniRef50_Q4P5N0 Cluster: Serine/threonine-protein kinase SMU1; n... 125 2e-27
UniRef50_Q00532 Cluster: Cyclin-dependent kinase-like 1; n=24; B... 125 2e-27
UniRef50_A7NWI3 Cluster: Chromosome chr5 scaffold_2, whole genom... 125 2e-27
UniRef50_Q57WI0 Cluster: Protein kinase, putative; n=1; Trypanos... 125 2e-27
UniRef50_Q54WX4 Cluster: Putative uncharacterized protein aurB; ... 125 2e-27
UniRef50_Q54R82 Cluster: Protein serine/threonine kinase; n=2; D... 125 2e-27
UniRef50_UPI0000F1EE77 Cluster: PREDICTED: similar to serine/thr... 124 3e-27
UniRef50_UPI0000499EFD Cluster: protein kinase; n=1; Entamoeba h... 124 3e-27
UniRef50_A7PSB1 Cluster: Chromosome chr14 scaffold_27, whole gen... 124 3e-27
UniRef50_Q9W179 Cluster: CG4527-PB, isoform B; n=9; Diptera|Rep:... 124 3e-27
UniRef50_Q6FJ06 Cluster: Candida glabrata strain CBS138 chromoso... 124 3e-27
UniRef50_UPI00004999DA Cluster: protein kinase; n=2; Entamoeba h... 124 4e-27
UniRef50_Q4STY5 Cluster: Chromosome 10 SCAF14066, whole genome s... 124 4e-27
UniRef50_Q23290 Cluster: Germinal center kinase family protein 2... 124 4e-27
UniRef50_Q5U8Z0 Cluster: Misshapen/NIKs-related kinase isoform b... 124 4e-27
UniRef50_Q8N4C8 Cluster: Misshapen-like kinase 1; n=114; Eumetaz... 124 4e-27
UniRef50_P38692 Cluster: Serine/threonine-protein kinase KIC1; n... 124 4e-27
UniRef50_Q33DX3 Cluster: Putative cyclic AMP-dependent protein k... 124 6e-27
UniRef50_UPI00006CB840 Cluster: Protein kinase domain containing... 123 7e-27
UniRef50_UPI000023D1D8 Cluster: hypothetical protein FG05484.1; ... 123 7e-27
UniRef50_Q0J228 Cluster: Os09g0383300 protein; n=5; Oryza sativa... 123 7e-27
UniRef50_Q869U1 Cluster: Similar to Arabidopsis thaliana (Mouse-... 123 7e-27
UniRef50_Q6CMA7 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 123 7e-27
UniRef50_A5DUG3 Cluster: Putative uncharacterized protein; n=1; ... 123 7e-27
UniRef50_Q4QGB0 Cluster: Mitogen-activated protein kinase kinase... 123 1e-26
UniRef50_Q2H8Z5 Cluster: Putative uncharacterized protein; n=2; ... 123 1e-26
UniRef50_Q5EAR9 Cluster: Zgc:152783 protein; n=10; Euteleostomi|... 122 1e-26
UniRef50_Q9STE0 Cluster: MAP3K epsilon 1 protein kinase; n=1; Br... 122 1e-26
UniRef50_Q10EQ9 Cluster: Protein kinase domain containing protei... 122 1e-26
UniRef50_Q55BN8 Cluster: Protein serine/threonine kinase; n=1; D... 122 1e-26
UniRef50_A2G0I5 Cluster: STE family protein kinase; n=2; Trichom... 122 1e-26
UniRef50_A2ED12 Cluster: CAMK family protein kinase; n=1; Tricho... 122 1e-26
UniRef50_Q6FKH4 Cluster: Similar to sp|P38692 Saccharomyces cere... 122 1e-26
UniRef50_Q59LK7 Cluster: Likely protein kinase; n=2; Saccharomyc... 122 1e-26
UniRef50_A7TL28 Cluster: Putative uncharacterized protein; n=1; ... 122 1e-26
UniRef50_UPI00006CFE83 Cluster: Protein kinase domain containing... 122 2e-26
UniRef50_Q56A46 Cluster: Zgc:113355; n=3; Clupeocephala|Rep: Zgc... 122 2e-26
UniRef50_Q584V3 Cluster: Protein kinase, putative; n=1; Trypanos... 122 2e-26
UniRef50_Q19KC5 Cluster: P21-activated kinase MAX-2; n=4; Caenor... 122 2e-26
UniRef50_Q6FSC4 Cluster: Similar to sp|P08458 Saccharomyces cere... 122 2e-26
UniRef50_Q68ST5 Cluster: P21 activated kinase-like protein; n=18... 122 2e-26
UniRef50_Q6FN53 Cluster: Serine/threonine-protein kinase STE20; ... 122 2e-26
UniRef50_O95819 Cluster: Mitogen-activated protein kinase kinase... 122 2e-26
UniRef50_O76039 Cluster: Cyclin-dependent kinase-like 5; n=22; D... 122 2e-26
UniRef50_UPI00006CDDE2 Cluster: Protein kinase domain containing... 122 2e-26
UniRef50_Q4RZ52 Cluster: Chromosome 7 SCAF14966, whole genome sh... 122 2e-26
UniRef50_A0DBL2 Cluster: Chromosome undetermined scaffold_44, wh... 122 2e-26
UniRef50_Q756N1 Cluster: AER223Cp; n=1; Eremothecium gossypii|Re... 122 2e-26
UniRef50_Q6IWN3 Cluster: P21-activated kinase Cla4; n=1; Ustilag... 122 2e-26
UniRef50_Q6BNF3 Cluster: Serine/threonine-protein kinase STE20; ... 122 2e-26
UniRef50_UPI0000498EBD Cluster: protein kinase; n=1; Entamoeba h... 121 3e-26
UniRef50_A2DL59 Cluster: AGC family protein kinase; n=1; Trichom... 121 3e-26
UniRef50_A0DPW4 Cluster: Chromosome undetermined scaffold_6, who... 121 3e-26
UniRef50_Q2HEZ5 Cluster: Putative uncharacterized protein; n=1; ... 121 3e-26
UniRef50_A6RH99 Cluster: Putative uncharacterized protein; n=1; ... 121 3e-26
UniRef50_Q6C3D7 Cluster: Serine/threonine-protein kinase STE20; ... 121 3e-26
UniRef50_P08458 Cluster: Sporulation-specific protein 1; n=3; Sa... 121 3e-26
UniRef50_P38991 Cluster: Spindle assembly checkpoint kinase; n=5... 121 3e-26
UniRef50_UPI0000DB74E3 Cluster: PREDICTED: similar to misshapen ... 121 4e-26
UniRef50_Q40541 Cluster: Protein kinase; n=1; Nicotiana tabacum|... 121 4e-26
UniRef50_Q0D8Z1 Cluster: Os07g0119000 protein; n=5; Magnoliophyt... 121 4e-26
UniRef50_A3C9K1 Cluster: Putative uncharacterized protein; n=1; ... 121 4e-26
UniRef50_Q24GE3 Cluster: Protein kinase domain containing protei... 121 4e-26
UniRef50_A7RY41 Cluster: Predicted protein; n=1; Nematostella ve... 121 4e-26
UniRef50_A0E7B2 Cluster: Chromosome undetermined scaffold_80, wh... 121 4e-26
UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, wh... 121 4e-26
UniRef50_A0CJ09 Cluster: Chromosome undetermined scaffold_19, wh... 121 4e-26
UniRef50_A0C3V8 Cluster: Chromosome undetermined scaffold_148, w... 121 4e-26
UniRef50_Q6C9X8 Cluster: Similar to sp|P08458 Saccharomyces cere... 121 4e-26
UniRef50_A5DW26 Cluster: Putative uncharacterized protein; n=1; ... 121 4e-26
UniRef50_Q9NQU5 Cluster: Serine/threonine-protein kinase PAK 6; ... 121 4e-26
UniRef50_Q12851 Cluster: Mitogen-activated protein kinase kinase... 121 4e-26
UniRef50_P41892 Cluster: Cell division control protein 7; n=1; S... 121 4e-26
UniRef50_UPI00015B5E1A Cluster: PREDICTED: similar to CG16973-PE... 120 5e-26
UniRef50_A7PXV1 Cluster: Chromosome chr15 scaffold_37, whole gen... 120 5e-26
UniRef50_Q8SYA1 Cluster: RH10407p; n=4; Endopterygota|Rep: RH104... 120 5e-26
UniRef50_Q55D99 Cluster: P21-activated protein kinase; n=3; Dict... 120 5e-26
UniRef50_A2E474 Cluster: AGC family protein kinase; n=1; Trichom... 120 5e-26
UniRef50_A1ZBH7 Cluster: CG7097-PA, isoform A; n=4; Eumetazoa|Re... 120 5e-26
UniRef50_Q5KP75 Cluster: Kinase, putative; n=2; Filobasidiella n... 120 5e-26
UniRef50_A0DTA2 Cluster: Chromosome undetermined scaffold_62, wh... 120 7e-26
UniRef50_Q9VXE5 Cluster: Serine/threonine-protein kinase PAK mbt... 120 7e-26
UniRef50_O14427 Cluster: Serine/threonine-protein kinase CLA4; n... 120 7e-26
UniRef50_Q24DN1 Cluster: Protein kinase domain containing protei... 120 9e-26
UniRef50_A4VD70 Cluster: Serine/threonine-protein kinase, putati... 120 9e-26
UniRef50_A0BP84 Cluster: Chromosome undetermined scaffold_12, wh... 120 9e-26
UniRef50_A7THU4 Cluster: Putative uncharacterized protein; n=1; ... 120 9e-26
UniRef50_P50527 Cluster: Serine/threonine-protein kinase shk1/pa... 120 9e-26
UniRef50_Q6C3J2 Cluster: Spindle assembly checkpoint kinase; n=1... 120 9e-26
UniRef50_UPI00006CC8B4 Cluster: Protein kinase domain containing... 119 1e-25
UniRef50_UPI0000499445 Cluster: protein kinase; n=1; Entamoeba h... 119 1e-25
UniRef50_A7NX40 Cluster: Chromosome chr5 scaffold_2, whole genom... 119 1e-25
UniRef50_Q6BG60 Cluster: Protein kinase, putative; n=2; Parameci... 119 1e-25
UniRef50_A2EEN0 Cluster: STE family protein kinase; n=1; Trichom... 119 1e-25
UniRef50_A0BZI1 Cluster: Chromosome undetermined scaffold_139, w... 119 1e-25
UniRef50_Q9HEL1 Cluster: Related to septation (SepH) gene; n=9; ... 119 1e-25
UniRef50_UPI00015B638D Cluster: PREDICTED: similar to aurora kin... 119 2e-25
UniRef50_Q23DB7 Cluster: Protein kinase domain containing protei... 119 2e-25
UniRef50_Q8W582 Cluster: At1g53570/F22G10_18; n=8; core eudicoty... 118 2e-25
UniRef50_Q54QI2 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-25
UniRef50_A7TG99 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-25
UniRef50_A5DPT3 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-25
UniRef50_O75011 Cluster: Serine/threonine-protein kinase nak1; n... 118 2e-25
UniRef50_UPI00006CBBFF Cluster: Protein kinase domain containing... 118 3e-25
UniRef50_Q4T4Q7 Cluster: Chromosome 3 SCAF9564, whole genome sho... 118 3e-25
UniRef50_Q24213 Cluster: P21-activated protein kinase 1 Dpak1; n... 118 3e-25
UniRef50_A5AJM4 Cluster: Putative uncharacterized protein; n=1; ... 118 4e-25
UniRef50_Q9W002 Cluster: CG16973-PA, isoform A; n=4; Diptera|Rep... 118 4e-25
UniRef50_A2EUZ8 Cluster: CAMK family protein kinase; n=1; Tricho... 118 4e-25
UniRef50_UPI000150A033 Cluster: Protein kinase domain containing... 117 5e-25
UniRef50_UPI000049980F Cluster: protein kinase; n=1; Entamoeba h... 117 5e-25
UniRef50_Q7QUE9 Cluster: GLP_59_15138_16382; n=2; Giardia intest... 117 5e-25
UniRef50_A2FIW7 Cluster: STE family protein kinase; n=1; Trichom... 117 5e-25
UniRef50_Q9LER4 Cluster: Protein kinase-like protein; n=5; Magno... 117 6e-25
UniRef50_A3B8E0 Cluster: Putative uncharacterized protein; n=3; ... 117 6e-25
UniRef50_Q9VMN3 Cluster: CG7236-PA; n=3; Endopterygota|Rep: CG72... 117 6e-25
UniRef50_Q54JG7 Cluster: Putative uncharacterized protein; n=1; ... 117 6e-25
UniRef50_A0DZB2 Cluster: Chromosome undetermined scaffold_7, who... 117 6e-25
UniRef50_A0CG41 Cluster: Chromosome undetermined scaffold_178, w... 117 6e-25
UniRef50_A0BXP1 Cluster: Chromosome undetermined scaffold_135, w... 117 6e-25
UniRef50_A7TPV4 Cluster: Putative uncharacterized protein; n=1; ... 117 6e-25
UniRef50_A3LPL1 Cluster: Predicted protein; n=2; Saccharomycetac... 117 6e-25
UniRef50_Q75DK7 Cluster: Serine/threonine-protein kinase STE20; ... 117 6e-25
UniRef50_Q58AU7 Cluster: Putative uncharacterized protein; n=3; ... 116 8e-25
UniRef50_Q4Q7P6 Cluster: Protein kinase, putative; n=3; Leishman... 116 8e-25
UniRef50_Q235Z4 Cluster: Protein kinase domain containing protei... 116 8e-25
UniRef50_Q0KHQ5 Cluster: CG14217-PD, isoform D; n=6; Diptera|Rep... 116 8e-25
UniRef50_A0BC68 Cluster: Chromosome undetermined scaffold_10, wh... 116 8e-25
UniRef50_Q7L7X3 Cluster: Serine/threonine-protein kinase TAO1; n... 116 8e-25
UniRef50_O95382 Cluster: Mitogen-activated protein kinase kinase... 116 8e-25
UniRef50_P27636 Cluster: Cell division control protein 15; n=3; ... 116 8e-25
UniRef50_A2DW86 Cluster: AGC family protein kinase; n=1; Trichom... 116 1e-24
UniRef50_A2DS63 Cluster: AGC family protein kinase; n=3; Trichom... 116 1e-24
UniRef50_A0DTL3 Cluster: Chromosome undetermined scaffold_63, wh... 116 1e-24
UniRef50_P28178 Cluster: Protein kinase 2; n=2; Dictyostelium di... 116 1e-24
UniRef50_UPI0000F20D35 Cluster: PREDICTED: p21-activated protein... 116 1e-24
UniRef50_UPI000049A19E Cluster: protein kinase; n=1; Entamoeba h... 116 1e-24
UniRef50_Q54PX0 Cluster: Putative uncharacterized protein; n=1; ... 116 1e-24
UniRef50_Q54FP0 Cluster: Putative uncharacterized protein mkcB; ... 116 1e-24
UniRef50_A1CZC9 Cluster: MAP kinase kinase kinase Ste11/SteC; n=... 116 1e-24
UniRef50_Q4WHP3 Cluster: Serine/threonine-protein kinase ste20; ... 116 1e-24
UniRef50_UPI0000D56E94 Cluster: PREDICTED: similar to cyclin-dep... 115 2e-24
UniRef50_Q24HP6 Cluster: Protein kinase domain containing protei... 115 2e-24
UniRef50_Q23KJ6 Cluster: Protein kinase domain containing protei... 115 2e-24
UniRef50_A2FJN1 Cluster: CAMK family protein kinase; n=1; Tricho... 115 2e-24
UniRef50_A2EAS8 Cluster: CAMK family protein kinase; n=1; Tricho... 115 2e-24
UniRef50_A0D283 Cluster: Chromosome undetermined scaffold_35, wh... 115 2e-24
UniRef50_Q1E0X5 Cluster: Putative uncharacterized protein; n=1; ... 115 2e-24
UniRef50_A5DV85 Cluster: Serine/threonine-protein kinase SCH9; n... 115 2e-24
UniRef50_O14965 Cluster: Serine/threonine-protein kinase 6; n=40... 115 2e-24
UniRef50_UPI00015B613B Cluster: PREDICTED: similar to ENSANGP000... 115 3e-24
UniRef50_Q93107 Cluster: Myosin I heavy chain kinase; n=1; Acant... 115 3e-24
UniRef50_Q4XNV1 Cluster: Rac-beta serine/threonine protein kinas... 115 3e-24
UniRef50_Q4E2T3 Cluster: Protein kinase, putative; n=1; Trypanos... 115 3e-24
UniRef50_Q9HFR3 Cluster: Mekk; n=1; Pneumocystis carinii|Rep: Me... 115 3e-24
UniRef50_Q01389 Cluster: Serine/threonine-protein kinase BCK1/SL... 115 3e-24
UniRef50_Q27393 Cluster: Aurora; n=7; Fungi/Metazoa group|Rep: A... 114 3e-24
UniRef50_A2EQE4 Cluster: STE family protein kinase; n=1; Trichom... 114 3e-24
UniRef50_A2DIX8 Cluster: STE family protein kinase; n=1; Trichom... 114 3e-24
UniRef50_A0BK55 Cluster: Chromosome undetermined scaffold_111, w... 114 3e-24
UniRef50_A7TQJ5 Cluster: Putative uncharacterized protein; n=1; ... 114 3e-24
UniRef50_A6S2W2 Cluster: Putative uncharacterized protein; n=1; ... 114 3e-24
UniRef50_Q7RZD3 Cluster: Serine/threonine-protein kinase ste-20;... 114 3e-24
UniRef50_P22612 Cluster: cAMP-dependent protein kinase, gamma-ca... 114 3e-24
UniRef50_A2XUW1 Cluster: Cyclin-dependent kinase G-2; n=9; Eukar... 114 3e-24
UniRef50_UPI0000DB76CC Cluster: PREDICTED: similar to serine/thr... 114 4e-24
UniRef50_UPI00006CB302 Cluster: Protein kinase domain containing... 114 4e-24
UniRef50_Q551M5 Cluster: Myosin heavy chain kinase; n=4; Dictyos... 114 4e-24
UniRef50_A7SJF2 Cluster: Predicted protein; n=2; Nematostella ve... 114 4e-24
UniRef50_A2DY61 Cluster: CAMK family protein kinase; n=1; Tricho... 114 4e-24
UniRef50_A2DQ28 Cluster: CMGC family protein kinase; n=1; Tricho... 114 4e-24
UniRef50_UPI000155CD84 Cluster: PREDICTED: similar to Mitogen-ac... 113 6e-24
UniRef50_UPI000069DCF9 Cluster: UPI000069DCF9 related cluster; n... 113 6e-24
UniRef50_Q8S3U7 Cluster: Protein kinase Fa2; n=1; Chlamydomonas ... 113 6e-24
UniRef50_A2Y9B1 Cluster: Putative uncharacterized protein; n=1; ... 113 6e-24
UniRef50_O96134 Cluster: Protein kinase, putative; n=4; Plasmodi... 113 6e-24
UniRef50_A0DV64 Cluster: Chromosome undetermined scaffold_65, wh... 113 6e-24
UniRef50_A0CVZ3 Cluster: Chromosome undetermined scaffold_3, who... 113 6e-24
UniRef50_Q5Y251 Cluster: STE11p; n=3; Tremellomycetes|Rep: STE11... 113 6e-24
UniRef50_P23561 Cluster: Serine/threonine-protein kinase STE11; ... 113 6e-24
UniRef50_Q9P286 Cluster: Serine/threonine-protein kinase PAK 7; ... 113 6e-24
UniRef50_Q92772 Cluster: Cyclin-dependent kinase-like 2; n=18; A... 113 6e-24
UniRef50_P28829 Cluster: Protein kinase byr2; n=3; Schizosacchar... 113 6e-24
UniRef50_UPI00015B6198 Cluster: PREDICTED: similar to serine/thr... 113 8e-24
UniRef50_UPI00015B49EE Cluster: PREDICTED: similar to LOC443693 ... 113 8e-24
UniRef50_Q6UPR0 Cluster: NIMA-related kinase 6; n=1; Chlamydomon... 113 8e-24
UniRef50_Q7QU56 Cluster: GLP_725_2794_9678; n=2; Eukaryota|Rep: ... 113 8e-24
UniRef50_Q4QEF5 Cluster: Protein kinase, putative; n=3; Leishman... 113 8e-24
UniRef50_Q22MG9 Cluster: Protein kinase domain containing protei... 113 8e-24
UniRef50_A2EN08 Cluster: STE family protein kinase; n=1; Trichom... 113 8e-24
UniRef50_A0CDF0 Cluster: Chromosome undetermined scaffold_17, wh... 113 8e-24
UniRef50_Q9HGS0 Cluster: CAMP-dependent protein kinase catalytic... 113 8e-24
UniRef50_Q5K7C2 Cluster: Protein kinase Sch9, putative; n=4; Aga... 113 8e-24
UniRef50_Q9NRP7 Cluster: Serine/threonine-protein kinase 36; n=2... 113 8e-24
UniRef50_UPI000049A05D Cluster: protein kinase; n=4; Entamoeba h... 113 1e-23
UniRef50_Q4R1K7 Cluster: Aurora kinase; n=5; Eukaryota|Rep: Auro... 113 1e-23
UniRef50_Q4DL90 Cluster: Rac serine-threonine kinase, putative; ... 113 1e-23
UniRef50_A4VDB2 Cluster: Serine/threonine protein kinase; n=1; T... 113 1e-23
UniRef50_A2EX40 Cluster: AGC family protein kinase; n=4; Trichom... 113 1e-23
UniRef50_A0C2Z2 Cluster: Chromosome undetermined scaffold_145, w... 113 1e-23
UniRef50_A6R4X2 Cluster: Negative regulator of the PHO system; n... 113 1e-23
UniRef50_A5E6H6 Cluster: Putative uncharacterized protein; n=1; ... 113 1e-23
UniRef50_A5DES9 Cluster: Putative uncharacterized protein; n=1; ... 113 1e-23
UniRef50_Q9UQB9 Cluster: Serine/threonine-protein kinase 13; n=8... 113 1e-23
UniRef50_UPI00006CB362 Cluster: Protein kinase domain containing... 112 1e-23
UniRef50_UPI000023D792 Cluster: hypothetical protein FG06326.1; ... 112 1e-23
UniRef50_Q9FGW5 Cluster: Protein kinase; n=2; Arabidopsis thalia... 112 1e-23
UniRef50_Q55GV3 Cluster: P21-activated protein kinase; n=2; Dict... 112 1e-23
UniRef50_Q4QAI6 Cluster: Protein kinase, putative; n=6; Trypanos... 112 1e-23
UniRef50_Q26334 Cluster: Serine/threonine protein kinase; n=2; E... 112 1e-23
UniRef50_Q19962 Cluster: Putative uncharacterized protein; n=3; ... 112 1e-23
UniRef50_Q18637 Cluster: Putative uncharacterized protein pak-2;... 112 1e-23
UniRef50_A0CGW2 Cluster: Chromosome undetermined scaffold_18, wh... 112 1e-23
UniRef50_Q4PH11 Cluster: Putative uncharacterized protein; n=1; ... 112 1e-23
UniRef50_P50530 Cluster: Serine/threonine-protein kinase sck1; n... 112 1e-23
UniRef50_Q99683 Cluster: Mitogen-activated protein kinase kinase... 112 1e-23
UniRef50_O88445 Cluster: Serine/threonine-protein kinase 13; n=7... 112 1e-23
UniRef50_UPI0000E47761 Cluster: PREDICTED: similar to serine/thr... 112 2e-23
UniRef50_Q1IIR5 Cluster: Serine/threonine protein kinase; n=1; A... 112 2e-23
UniRef50_A7L4B0 Cluster: Protein kinase; n=6; Eukaryota|Rep: Pro... 112 2e-23
UniRef50_Q21271 Cluster: Aurora/ipl1 related kinase protein 1; n... 112 2e-23
UniRef50_Q6CBU3 Cluster: Yarrowia lipolytica chromosome C of str... 112 2e-23
UniRef50_A4RDS9 Cluster: Putative uncharacterized protein; n=1; ... 112 2e-23
UniRef50_P11792 Cluster: Serine/threonine-protein kinase SCH9; n... 112 2e-23
UniRef50_P51956 Cluster: Serine/threonine-protein kinase Nek3; n... 112 2e-23
UniRef50_A2EJW2 Cluster: CAMK family protein kinase; n=1; Tricho... 111 2e-23
UniRef50_A2E6I9 Cluster: AGC family protein kinase; n=2; Trichom... 111 2e-23
UniRef50_A0BMA9 Cluster: Chromosome undetermined scaffold_116, w... 111 2e-23
UniRef50_A0BEK6 Cluster: Chromosome undetermined scaffold_102, w... 111 2e-23
UniRef50_Q7S4G0 Cluster: Putative uncharacterized protein NCU022... 111 2e-23
UniRef50_Q4PHE2 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23
UniRef50_A7TJU8 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23
UniRef50_P50613 Cluster: Cell division protein kinase 7; n=32; E... 111 2e-23
UniRef50_Q9VE37 Cluster: CG7717-PA, isoform A; n=6; Eumetazoa|Re... 111 3e-23
UniRef50_Q8I182 Cluster: Pk92B-PA; n=4; Endopterygota|Rep: Pk92B... 111 3e-23
UniRef50_Q233Z3 Cluster: Protein kinase domain containing protei... 111 3e-23
UniRef50_A2EZG8 Cluster: AGC family protein kinase; n=1; Trichom... 111 3e-23
UniRef50_A2DW97 Cluster: CAMK family protein kinase; n=2; Tricho... 111 3e-23
UniRef50_A0CU69 Cluster: Chromosome undetermined scaffold_28, wh... 111 3e-23
UniRef50_Q6CK22 Cluster: Similarity; n=2; Kluyveromyces lactis|R... 111 3e-23
UniRef50_Q55U80 Cluster: Putative uncharacterized protein; n=3; ... 111 3e-23
UniRef50_Q39030 Cluster: Serine/threonine-protein kinase AtPK19;... 111 3e-23
UniRef50_UPI0000DA318D Cluster: PREDICTED: similar to mitogen-ac... 111 4e-23
UniRef50_Q3E9E3 Cluster: Uncharacterized protein At5g18700.1; n=... 111 4e-23
UniRef50_Q4Q6Y5 Cluster: Protein kinase-like protein; n=3; Leish... 111 4e-23
UniRef50_Q4Q5Q9 Cluster: Protein kinase, putative; n=3; Leishman... 111 4e-23
UniRef50_A2G1Q9 Cluster: AGC family protein kinase; n=1; Trichom... 111 4e-23
UniRef50_A0BG19 Cluster: Chromosome undetermined scaffold_105, w... 111 4e-23
UniRef50_Q5B3J3 Cluster: Putative uncharacterized protein; n=1; ... 111 4e-23
UniRef50_Q4WXY0 Cluster: MAP kinase kinase kinase (Bck1), putati... 111 4e-23
UniRef50_Q4PCB9 Cluster: Putative uncharacterized protein; n=1; ... 111 4e-23
UniRef50_Q2UNA7 Cluster: Ribosomal protein S6 kinase and related... 111 4e-23
UniRef50_Q99759 Cluster: Mitogen-activated protein kinase kinase... 111 4e-23
UniRef50_UPI000065EE71 Cluster: MAP/microtubule affinity-regulat... 110 6e-23
UniRef50_A2BFU1 Cluster: Novel protein; n=6; Euteleostomi|Rep: N... 110 6e-23
UniRef50_Q228S4 Cluster: Protein kinase domain containing protei... 110 6e-23
UniRef50_A2FLX7 Cluster: AGC family protein kinase; n=4; Trichom... 110 6e-23
UniRef50_A0CNT4 Cluster: Chromosome undetermined scaffold_22, wh... 110 6e-23
UniRef50_A0BD03 Cluster: Chromosome undetermined scaffold_10, wh... 110 6e-23
UniRef50_Q9HFT9 Cluster: Ste11alpha protein; n=5; Tremellomycete... 110 6e-23
UniRef50_P05986 Cluster: cAMP-dependent protein kinase type 3; n... 110 6e-23
UniRef50_UPI00015A44B1 Cluster: hypothetical protein LOC325034; ... 110 7e-23
UniRef50_Q6UPR2 Cluster: NIMA-related kinase 4; n=1; Chlamydomon... 110 7e-23
UniRef50_Q7KSD3 Cluster: CG7693-PA, isoform A; n=6; Bilateria|Re... 110 7e-23
UniRef50_Q675R9 Cluster: Cyclin-dependent kinase-like 1; n=1; Oi... 110 7e-23
UniRef50_A2F0I9 Cluster: AGC family protein kinase; n=1; Trichom... 110 7e-23
UniRef50_A2ET74 Cluster: AGC family protein kinase; n=1; Trichom... 110 7e-23
UniRef50_A2DVU2 Cluster: CAMK family protein kinase; n=1; Tricho... 110 7e-23
UniRef50_A0E7T5 Cluster: Chromosome undetermined scaffold_81, wh... 110 7e-23
UniRef50_Q8XJL8 Cluster: Probable serine/threonine-protein kinas... 110 7e-23
UniRef50_P51955 Cluster: Serine/threonine-protein kinase Nek2; n... 110 7e-23
UniRef50_Q9QUK0 Cluster: Cyclin-dependent kinase-like 2; n=8; Th... 110 7e-23
UniRef50_UPI000150A708 Cluster: Protein kinase domain containing... 109 1e-22
UniRef50_UPI00006CAF11 Cluster: Protein kinase domain containing... 109 1e-22
UniRef50_Q0SBU5 Cluster: Possible protein kinase; n=1; Rhodococc... 109 1e-22
UniRef50_Q8I6M5 Cluster: DASK1; n=9; Diptera|Rep: DASK1 - Drosop... 109 1e-22
UniRef50_Q6BFB4 Cluster: Protein kinase, putative; n=3; Parameci... 109 1e-22
UniRef50_A2DB15 Cluster: AGC family protein kinase; n=1; Trichom... 109 1e-22
UniRef50_Q8X1F0 Cluster: PAK1 kinase; n=3; Filobasidiella neofor... 109 1e-22
UniRef50_Q8TGH8 Cluster: Bck1-like MAP kinase kinase kinase; n=1... 109 1e-22
UniRef50_Q6CVC4 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 109 1e-22
UniRef50_Q6C936 Cluster: Yarrowia lipolytica chromosome D of str... 109 1e-22
UniRef50_Q5KM47 Cluster: CAMP-dependent protein kinase, putative... 109 1e-22
UniRef50_A6R8E8 Cluster: Putative uncharacterized protein; n=1; ... 109 1e-22
UniRef50_A1CR23 Cluster: CAMP-dependent protein kinase, putative... 109 1e-22
UniRef50_Q9UEW8 Cluster: STE20/SPS1-related proline-alanine-rich... 109 1e-22
UniRef50_UPI0000E809AA Cluster: PREDICTED: similar to regulated ... 109 1e-22
UniRef50_UPI00006CB772 Cluster: Protein kinase domain containing... 109 1e-22
UniRef50_UPI0000F348D6 Cluster: Serine/threonine-protein kinase ... 109 1e-22
UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5; ... 109 1e-22
UniRef50_Q4Q4U7 Cluster: Mitogen-activated protein kinase, putat... 109 1e-22
UniRef50_A0BQV0 Cluster: Chromosome undetermined scaffold_121, w... 109 1e-22
UniRef50_Q9P496 Cluster: Protein kinase; n=1; Yarrowia lipolytic... 109 1e-22
UniRef50_A6SDS8 Cluster: Putative uncharacterized protein; n=1; ... 109 1e-22
UniRef50_UPI0000E46CEF Cluster: PREDICTED: similar to MEK5alpha-... 109 2e-22
UniRef50_UPI000051AD36 Cluster: PREDICTED: similar to cyclin-dep... 109 2e-22
UniRef50_UPI00006A01A3 Cluster: UPI00006A01A3 related cluster; n... 109 2e-22
>UniRef50_Q02750 Cluster: Dual specificity mitogen-activated protein
kinase kinase 1; n=88; Eumetazoa|Rep: Dual specificity
mitogen-activated protein kinase kinase 1 - Homo sapiens
(Human)
Length = 393
Score = 545 bits (1344), Expect = e-153
Identities = 264/381 (69%), Positives = 311/381 (81%), Gaps = 16/381 (4%)
Query: 30 TP-QLKSATANERQGLAGKSKTSIEALTERLEQIEMDDTQRRRIEVFLCQKEKIGELSDD 88
TP QL A ++T++EAL ++LE++E+D+ QR+R+E FL QK+K+GEL DD
Sbjct: 7 TPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDD 66
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148
DFEK+ ELG GNGGVV KV HK +GL+MARKLIHLE+KPAI+ QIIREL+VLHECN +I
Sbjct: 67 DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYI 126
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
VGFYGAFYSDGEISICME+MDGGSLD +LKKAGRIPE ILG ++ AV+KGL+YLR+KH I
Sbjct: 127 VGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKI 186
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDI 268
MHRDVKPSNILVNS GEIK+CDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDI
Sbjct: 187 MHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDI 246
Query: 269 WSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNE---------DHSPGQ-----APNSPR 314
WS+GLSLVEMA+G YPIPPPDAK L +FG Q E +PG+ +S
Sbjct: 247 WSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRP 306
Query: 315 PMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEA 374
PMAIFELLDYIVNEPPPKLPSG+FS EF+DFV++CL KNP ERADLK LM H +I++++A
Sbjct: 307 PMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDA 366
Query: 375 EKVDIAGWVCKTMDL-MPSTP 394
E+VD AGW+C T+ L PSTP
Sbjct: 367 EEVDFAGWLCSTIGLNQPSTP 387
>UniRef50_Q99078 Cluster: Dual specificity protein kinase FUZ7; n=1;
Ustilago maydis|Rep: Dual specificity protein kinase
FUZ7 - Ustilago maydis (Smut fungus)
Length = 435
Score = 305 bits (749), Expect = 1e-81
Identities = 156/328 (47%), Positives = 215/328 (65%), Gaps = 29/328 (8%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
+L ++D + L ELG GNGG V KV H+ +G +MA+K++ ++ KP+++KQI+REL++LHEC
Sbjct: 103 DLKNEDLKTLSELGAGNGGTVTKVLHEKSGTVMAKKVVFIDAKPSVRKQILRELQILHEC 162
Query: 144 NFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLR 203
N +IV FYGA+ ++ I +CME+M SLD I KK G I I G I AV GL+YL
Sbjct: 163 NSPYIVSFYGAYLNEPHICMCMEFMQKDSLDGIYKKYGPISPEICGKIAVAVSHGLTYLY 222
Query: 204 DKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYS 263
D H I+HRDVKPSNILVN G+IKICDFGVSG+LI+S+A++FVGT +YMSPER+QG YS
Sbjct: 223 DVHRIIHRDVKPSNILVNGAGQIKICDFGVSGELINSIADTFVGTSTYMSPERIQGDQYS 282
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPD----------------AKTLAA------IFGGQN 301
V+SD+WSLG+S++E+A+G +P + A TL+ I GQN
Sbjct: 283 VKSDVWSLGVSIIELALGRFPFAENEEDDDSDADNNYTNEDLAGTLSPTKPAPMISLGQN 342
Query: 302 EDHSPGQAP-------NSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNP 354
E ++ S M+I +LL +IVNEPPPKLP G F ++FV+ CL K+P
Sbjct: 343 EKQRRRKSKPAGVSLEGSSHQMSILDLLQHIVNEPPPKLPEGRFPKHMEEFVNLCLLKDP 402
Query: 355 DERADLKTLMNHEWIRKAEAEKVDIAGW 382
+R K L H+++ A+A KVD+ W
Sbjct: 403 AKRPTPKDLTKHQYVIDADAAKVDLQAW 430
>UniRef50_Q5KKP1 Cluster: MAP kinase kinase, putative; n=4;
Tremellomycetes|Rep: MAP kinase kinase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 509
Score = 300 bits (737), Expect = 4e-80
Identities = 172/397 (43%), Positives = 239/397 (60%), Gaps = 39/397 (9%)
Query: 10 NLTLPPGSIDTN--PAATPSNMTPQLKSATANERQGLAGKSKTSIEALTERLEQIEMDDT 67
NL L S +N P A S Q S+ A+ GLA K K+ + E D
Sbjct: 71 NLQLSSRSTGSNHSPEALDSPRAFQSDSSVAS---GLAKKEKSR--------DGKERGDK 119
Query: 68 QRRRIEVFLCQKEKIGE--LSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEV 125
++R+ + K+K GE + D+D E L +LG GNGG V KV +K +MARKLI ++
Sbjct: 120 EKRKKK----HKDKDGEDLVKDEDLEILHDLGAGNGGTVTKVWNKKRKCVMARKLILVDA 175
Query: 126 KPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPE 185
KP+I+KQI+REL+++++C+ +IVG+YG F D + I ME+MD GSLD I + G I
Sbjct: 176 KPSIRKQILRELQIMNDCDSPYIVGYYGCFPVDVHVGIVMEFMDAGSLDYIYRHHGAIDI 235
Query: 186 SILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSF 245
I+G + AVL+GL YL DKH I+HRD+KPSN+L N+ GEIKICDFGVSG+LI+S+AN+F
Sbjct: 236 DIVGKVAQAVLEGLIYLYDKHRIIHRDIKPSNVLANTRGEIKICDFGVSGELINSIANTF 295
Query: 246 VGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPI-PPPDAKTLAAIFGG----- 299
VGT +YMSPER+QG Y+++SDIWSLG+SL+E+A+G +P PD++ L+
Sbjct: 296 VGTSTYMSPERIQGAPYTIKSDIWSLGISLIELAVGRFPFSDSPDSEELSPSVSDFDPDP 355
Query: 300 ------------QNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPS--GIFSDEFKDF 345
N H+ P M+I +LL +IVNEP P+L S F E F
Sbjct: 356 TLPRSVRRPKIESNSRHNGVSQSGGPHAMSILDLLQHIVNEPAPRLASRRRRFPQEAVAF 415
Query: 346 VDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGW 382
V+ CL K+PD+R K L++ WI + K D+ W
Sbjct: 416 VEGCLIKDPDQRRSPKELLSSSWITNLKTTKEDLQTW 452
>UniRef50_Q9Y7W8 Cluster: MAP kinase kinase; n=1; Yarrowia
lipolytica|Rep: MAP kinase kinase - Yarrowia lipolytica
(Candida lipolytica)
Length = 460
Score = 285 bits (700), Expect = 1e-75
Identities = 145/303 (47%), Positives = 204/303 (67%), Gaps = 25/303 (8%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
++ D + ELG GNGG V +V H TG +MA+K+IH+ K A+++QI+REL ++HEC
Sbjct: 174 DIRAQDLRTIQELGAGNGGSVSRVEHIPTGAVMAKKVIHIGGKEAVRRQILRELHIMHEC 233
Query: 144 NFAHIVGFYGAFY--SDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201
+ +IV FYGAF S G++ +CME+MD G LD I KKAG + E I+G IT AV++GL+Y
Sbjct: 234 DSPYIVSFYGAFINESSGDVVMCMEFMDCGHLDRIYKKAGPLTEEIVGHITVAVVEGLTY 293
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH 261
L ++H I+HRDVKPSNILVNS+G+IK+CDFGVSG+LI+S+A++FVGT +YMSPER+QG +
Sbjct: 294 LYNEHRIVHRDVKPSNILVNSHGQIKLCDFGVSGELINSIADTFVGTSTYMSPERIQGGN 353
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
Y+V+SD+WSLG+SL+E+ +G +P A + PM I +L
Sbjct: 354 YTVKSDVWSLGISLLELLLGKFPF---------------------DMANGAVGPMGILDL 392
Query: 322 LDYIVNEPPPKLPS--GIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDI 379
L IVNEPPP LP+ FS + FVDRCL K P+ + + +I + A++VD+
Sbjct: 393 LQRIVNEPPPTLPAEDTRFSPVCRRFVDRCLVKEPERPSPQQLHPTMPFIITSRAKQVDM 452
Query: 380 AGW 382
W
Sbjct: 453 KAW 455
>UniRef50_Q6GX81 Cluster: Mitogen activated protein kinase kinase 2;
n=8; Pezizomycotina|Rep: Mitogen activated protein
kinase kinase 2 - Cryphonectria parasitica (Chesnut
blight fungus) (Endothiaparasitica)
Length = 540
Score = 280 bits (687), Expect = 4e-74
Identities = 142/308 (46%), Positives = 200/308 (64%), Gaps = 20/308 (6%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
+L +D E + +LG GNGG V KV+ T MARK+IH+E K ++K+I+REL+++H C
Sbjct: 60 DLRPEDLEIIKDLGSGNGGTVSKVKRIPTNTTMARKVIHVEAKREMRKRIVRELQIMHNC 119
Query: 144 NFAHIVGFYGAFYSDG-EISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202
+ HIV FYGAF +D ++ +CMEYMD GSLD + + G + +LG I A L GL+YL
Sbjct: 120 HCEHIVTFYGAFLNDNNDVIMCMEYMDVGSLDRVSRVFGPVRVDVLGKIAEATLGGLTYL 179
Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY 262
KH IMHRD+KPSNILVNS G IK+CDFGVSG+LI+S+A++FVGT +YM+PER+QG Y
Sbjct: 180 YYKHHIMHRDIKPSNILVNSRGHIKLCDFGVSGELINSVADTFVGTSTYMAPERIQGEKY 239
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322
+V+SD+WS GLS++E+AIG +P +E S +A P I +LL
Sbjct: 240 TVKSDVWSFGLSIMELAIGKFPF-------------AASEQLSDAEA----APAGILDLL 282
Query: 323 DYIVNEPPPKLP-SGIFSDEFKDFVDRCLKKNPDERADLKTLMNHE-WIRKAEAEKVDIA 380
IV+EP PKLP S F +D + +CL K PD+R + L + + +++ A+ VD+
Sbjct: 283 QQIVHEPAPKLPKSDAFPQILEDMIQKCLLKTPDDRPTPQELYDRDPFVQAAKRTPVDLR 342
Query: 381 GWVCKTMD 388
W M+
Sbjct: 343 EWAVSLME 350
>UniRef50_Q0MQZ3 Cluster: STE7-like protein; n=14; Ascomycota|Rep:
STE7-like protein - Penicillium marneffei
Length = 559
Score = 277 bits (678), Expect = 5e-73
Identities = 144/307 (46%), Positives = 205/307 (66%), Gaps = 18/307 (5%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
+L +D L E+G GNGG V KV H +T ++MARK+I ++VK I+KQI+REL+V H+C
Sbjct: 61 DLRSEDLVTLKEVGAGNGGTVAKVMHATTKVVMARKIIRVDVKENIRKQILRELQVGHDC 120
Query: 144 NFAHIVGFYGAFYSDG-EISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202
N +IV FYGAF ++ +I +CMEYMD GSLD I K+ G + +LG IT ++L GL YL
Sbjct: 121 NSPYIVTFYGAFQNESRDIVLCMEYMDCGSLDRISKEFGPVRIDVLGKITESILAGLVYL 180
Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY 262
+ H IMHRD+KPSN+LVNS G IK+CDFGV+ + ++S+A++FVGT +YM+PER+QG Y
Sbjct: 181 YENHRIMHRDIKPSNVLVNSRGNIKLCDFGVATETVNSVADTFVGTSTYMAPERIQGGAY 240
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322
+V+SD+WS+GL+++E+A+G +P DA AA + S G PM I +LL
Sbjct: 241 TVRSDVWSVGLTVMELAVGRFPF---DATDSAA-----GDRASAG-------PMGILDLL 285
Query: 323 DYIVNEPPPKLP-SGIFSDEFKDFVDRCLKKNPDERADLKTLMNHE-WIRKAEAEKVDIA 380
IV+EP PKLP S F +FV +CL K +ER + L + + +++ A+ VD+
Sbjct: 286 QQIVHEPAPKLPKSDAFPPILHEFVAKCLLKKSEERPTPRELYDKDAFLQAAKRTPVDLQ 345
Query: 381 GWVCKTM 387
W K M
Sbjct: 346 KWARKMM 352
>UniRef50_P10506 Cluster: Protein kinase byr1; n=1;
Schizosaccharomyces pombe|Rep: Protein kinase byr1 -
Schizosaccharomyces pombe (Fission yeast)
Length = 340
Score = 262 bits (641), Expect = 2e-68
Identities = 140/301 (46%), Positives = 194/301 (64%), Gaps = 25/301 (8%)
Query: 82 IGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLH 141
I +L + E + LG+GNGG V V+H++ + MARK +++ ++KQI+REL VLH
Sbjct: 58 ISDLDNSSLEVVRHLGEGNGGAVSLVKHRN--IFMARKTVYVGSDSKLQKQILRELGVLH 115
Query: 142 ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201
C +IVGFYGAF IS+CMEYMD GSLD IL++ G IP ILG I ++++KGL Y
Sbjct: 116 HCRSPYIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILGKIINSMVKGLIY 175
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH 261
L + I+HRD+KPSN++VNS GEIK+CDFGVSG+L++S+A +FVGT +YMSPER++G
Sbjct: 176 LYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGELVNSVAQTFVGTSTYMSPERIRGGK 235
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
Y+V+SDIWSLG+S++E+A P + N D S G I +L
Sbjct: 236 YTVKSDIWSLGISIIELATQELP------------WSFSNIDDSIG----------ILDL 273
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAG 381
L IV E PP+LPS F ++ + FVD CL K+P RA + L + ++A VD+A
Sbjct: 274 LHCIVQEEPPRLPSS-FPEDLRLFVDACLHKDPTLRASPQQLCAMPYFQQALMINVDLAS 332
Query: 382 W 382
W
Sbjct: 333 W 333
>UniRef50_Q13163 Cluster: Dual specificity mitogen-activated protein
kinase kinase 5; n=50; Eumetazoa|Rep: Dual specificity
mitogen-activated protein kinase kinase 5 - Homo sapiens
(Human)
Length = 448
Score = 256 bits (626), Expect = 1e-66
Identities = 128/307 (41%), Positives = 195/307 (63%), Gaps = 27/307 (8%)
Query: 83 GELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE 142
G++++ D LG GNGG V K H +G I+A K+I L++ ++KQI+ EL++L++
Sbjct: 159 GQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYK 218
Query: 143 CNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202
C+ ++I+GFYGAF+ + ISIC E+MDGGSLD+ K +PE +LG I AV+KGL+YL
Sbjct: 219 CDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRK----MPEHVLGRIAVAVVKGLTYL 274
Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY 262
I+HRDVKPSN+LVN+ G++K+CDFGVS QL++S+A ++VGT +YM+PER+ G Y
Sbjct: 275 WSLK-ILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQY 333
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322
+ SD+WSLG+S +E+A+G +P P Q + + +LL
Sbjct: 334 GIHSDVWSLGISFMELALGRFPYP---------------------QIQKNQGSLMPLQLL 372
Query: 323 DYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI-RKAEAEKVDIAG 381
IV+E P LP G FS+ F F+ +C++K P ER + LM H +I + + ++
Sbjct: 373 QCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSM 432
Query: 382 WVCKTMD 388
WVC+ ++
Sbjct: 433 WVCRALE 439
>UniRef50_Q96W50 Cluster: Protein kinase Pbs2p; n=14; Fungi/Metazoa
group|Rep: Protein kinase Pbs2p - Debaryomyces hansenii
(Yeast) (Torulaspora hansenii)
Length = 683
Score = 254 bits (623), Expect = 2e-66
Identities = 150/373 (40%), Positives = 213/373 (57%), Gaps = 34/373 (9%)
Query: 5 SKNKLNLTLPPGSIDTNPAATPSNMTPQLKSATANERQGLAGKSKTSIEALTERLEQIEM 64
S++ N S+D++ +++ + + + + QGL ++ + L
Sbjct: 263 SQSNSNTNSTASSLDSSGSSSTAGTNNETNQSKKPQLQGLFANYSKYVDIKSGSLNFAGK 322
Query: 65 DDTQRRRIEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE 124
+ I+ FL + +S ++ E L ELG GN GVV+KV HK TG++MA K + LE
Sbjct: 323 ASLHSKGID-FL--SGLLFRISLEELEFLEELGHGNYGVVLKVLHKPTGVLMAMKEVRLE 379
Query: 125 VKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLIL-KKAGRI 183
+ QI+ EL++LH+C+ +IV FYGAF+ +G + +CMEYMDGGSLD I K G
Sbjct: 380 LDETKFTQILMELEILHKCDSPYIVDFYGAFFVEGAVYMCMEYMDGGSLDKIYGKDDGVK 439
Query: 184 PESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN 243
E+ L IT V+ GL L+D+H I+HRDVKP+NILVNS G++K+CDFGVSG L+ S+A
Sbjct: 440 DEACLAYITECVISGLKELKDEHNIIHRDVKPTNILVNSLGKVKLCDFGVSGNLVASLAK 499
Query: 244 SFVGTRSYMSPERLQG-----THYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFG 298
+ +G +SYM+PER++ YSVQSDIWSLGLS++E+A G YP P A +G
Sbjct: 500 TNIGCQSYMAPERIKSLSPTDNTYSVQSDIWSLGLSILEIAAGHYPYP-------AETYG 552
Query: 299 GQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERA 358
IF L IV+ PPKL IFS + + F+ CL KNPD R
Sbjct: 553 N------------------IFSQLSAIVDGDPPKLDPKIFSKDAQLFIKSCLNKNPDLRP 594
Query: 359 DLKTLMNHEWIRK 371
TL+ H W+ K
Sbjct: 595 SYATLLKHPWLVK 607
>UniRef50_P08018 Cluster: MAP kinase kinase PBS2; n=7;
Saccharomycetales|Rep: MAP kinase kinase PBS2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 668
Score = 254 bits (623), Expect = 2e-66
Identities = 139/310 (44%), Positives = 195/310 (62%), Gaps = 34/310 (10%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
D+ E L ELG GN G V KV HK T +IMA K + LE+ A +QI+ EL+VLH+CN +
Sbjct: 358 DELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKCNSPY 417
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKA---GRIPESILGTITSAVLKGLSYLRD 204
IV FYGAF+ +G + +CMEYMDGGSLD I ++ G I E L I +AV+ GL L++
Sbjct: 418 IVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKE 477
Query: 205 KHAIMHRDVKPSNILVNSN-GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH-- 261
+H I+HRDVKP+NIL ++N G +K+CDFGVSG L+ S+A + +G +SYM+PER++ +
Sbjct: 478 QHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPD 537
Query: 262 ---YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
Y+VQSDIWSLGLS++EMA+G YP PP + D+ I
Sbjct: 538 RATYTVQSDIWSLGLSILEMALGRYPYPP------------ETYDN-------------I 572
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVD 378
F L IV+ PPP+LPS FS + +DFV CL+K P+ R L H W+ K + V
Sbjct: 573 FSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWLVKYRNQDVH 632
Query: 379 IAGWVCKTMD 388
++ ++ + ++
Sbjct: 633 MSEYITERLE 642
>UniRef50_Q6CEG1 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 726
Score = 248 bits (608), Expect = 2e-64
Identities = 133/306 (43%), Positives = 191/306 (62%), Gaps = 33/306 (10%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
D+ E LGELG+GN G V KV HK TG+ MA K + LE+ A QII EL +LH+C +
Sbjct: 399 DELEPLGELGRGNYGTVTKVLHKPTGITMAMKEVKLELDTAKFAQIIMELDILHKCESPY 458
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
IV F+GAF+ +G + C+EYMDGGSLD + AG + E L IT +V++GL +L+++H
Sbjct: 459 IVDFFGAFFVEGAVYECIEYMDGGSLDKVY--AGGVDEPCLAAITDSVVRGLMFLKEEHN 516
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQ-----GTHY 262
I+HRDVKP+NIL+N+ G++K+CDFGVSG L+ S A++ +G +SYM+PER+ Y
Sbjct: 517 IIHRDVKPTNILINTEGKVKLCDFGVSGNLVASKASTVIGCQSYMAPERIHNPDSGNVTY 576
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322
+ SDIWSLG+S++E+A G YP PP +A N+ +F L
Sbjct: 577 TANSDIWSLGVSILEIAQGSYPYPP--------------------EAYNN-----VFAQL 611
Query: 323 DYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGW 382
IV+ PP+L FS E +DFV +CL+K P +R + L+ H W++K V +A +
Sbjct: 612 RAIVSGDPPQLAER-FSPEARDFVAQCLQKKPYQRPTYQQLLEHPWLKKYRGVDVGMADF 670
Query: 383 VCKTMD 388
V K ++
Sbjct: 671 VKKALE 676
>UniRef50_Q4P4U9 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 822
Score = 243 bits (594), Expect = 8e-63
Identities = 136/308 (44%), Positives = 191/308 (62%), Gaps = 37/308 (12%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148
+FE L LG+G G V KVRH+ TGLIMA+K I PAI +QI+REL C+ +I
Sbjct: 363 NFEMLSRLGEGASGEVHKVRHRPTGLIMAKKTISTSPNPAIHRQILRELAFNRSCHSDYI 422
Query: 149 VGFYGAFYS--DGEISICMEYMDGGSLDLILKKA----GRIPESILGTITSAVLKGLSYL 202
V +YGAF D I+ICMEY + GSLD I KK GR E +LG + VLKGLSYL
Sbjct: 423 VRYYGAFLEEQDTSIAICMEYAEAGSLDAIYKKVKSRNGRTGEKVLGKVAECVLKGLSYL 482
Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY 262
++ I+HRD+KPSNI+V G+IK+CDFGVSG+LI+S+A +F GT YM+PER++G Y
Sbjct: 483 HERK-IIHRDIKPSNIVVTRQGQIKLCDFGVSGELINSVAGTFTGTSFYMAPERIRGLAY 541
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322
++ SD+WSLGL+++E+A +P P + G+ P P +LL
Sbjct: 542 TITSDVWSLGLTILEVASNRFPFP------------------AEGEPPLGP-----IDLL 578
Query: 323 DYIVNEPPPKL----PSGI-FSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAE-- 375
Y+VN P+L +G+ +S +DF++RCL+K P +R +++H +IRK+E
Sbjct: 579 SYVVNMKVPELQDDEKAGVKWSRALRDFIERCLEKEPTKRPGPHKMISHPFIRKSETRQP 638
Query: 376 KVDIAGWV 383
+ DIA +V
Sbjct: 639 QPDIAKFV 646
>UniRef50_Q9S7U9 Cluster: Mitogen-activated protein kinase kinase 2;
n=36; Magnoliophyta|Rep: Mitogen-activated protein
kinase kinase 2 - Arabidopsis thaliana (Mouse-ear cress)
Length = 363
Score = 241 bits (591), Expect = 2e-62
Identities = 128/301 (42%), Positives = 184/301 (61%), Gaps = 23/301 (7%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
+LS D + + +G+G+ GVV V+HK TG A K+I L + AI+K I +ELK+
Sbjct: 64 QLSLSDLDMVKVIGKGSSGVVQLVQHKWTGQFFALKVIQLNIDEAIRKAIAQELKINQSS 123
Query: 144 NFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLR 203
++V Y +FY +G IS+ +EYMDGGSL LK IP+S L I VL+GL YL
Sbjct: 124 QCPNLVTSYQSFYDNGAISLILEYMDGGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLH 183
Query: 204 DKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTH 261
I+HRD+KPSN+L+N GE+KI DFGVS + ++ +AN+FVGT +YMSPER+ G
Sbjct: 184 HDRHIIHRDLKPSNLLINHRGEVKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVGNK 243
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
Y +SDIWSLGL ++E A G +P PP+ Q E + ++FEL
Sbjct: 244 YGNKSDIWSLGLVVLECATGKFPYAPPN----------QEETWT-----------SVFEL 282
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAG 381
++ IV++PPP LPSG FS E F+ CL+K+P+ R+ K LM H ++ K + +++A
Sbjct: 283 MEAIVDQPPPALPSGNFSPELSSFISTCLQKDPNSRSSAKELMEHPFLNKYDYSGINLAS 342
Query: 382 W 382
+
Sbjct: 343 Y 343
>UniRef50_P33886 Cluster: Protein kinase wis1; n=1;
Schizosaccharomyces pombe|Rep: Protein kinase wis1 -
Schizosaccharomyces pombe (Fission yeast)
Length = 605
Score = 240 bits (588), Expect = 4e-62
Identities = 133/298 (44%), Positives = 184/298 (61%), Gaps = 34/298 (11%)
Query: 92 KLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGF 151
KL ELG+GN GVV K H+ TG+ MA K I L ++ A QII EL +LH+ +IV F
Sbjct: 322 KLEELGKGNYGVVYKALHQPTGVTMALKEIRLSLEEATFNQIIMELDILHKAVSPYIVDF 381
Query: 152 YGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHR 211
YGAF+ +G + ICMEYMD GS+D L G E +L AV++GL L+++H I+HR
Sbjct: 382 YGAFFVEGSVFICMEYMDAGSMDK-LYAGGIKDEGVLARTAYAVVQGLKTLKEEHNIIHR 440
Query: 212 DVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQ------GT-HYSV 264
DVKP+N+LVNSNG++K+CDFGVSG L+ S++ + +G +SYM+PER++ G Y+V
Sbjct: 441 DVKPTNVLVNSNGQVKLCDFGVSGNLVASISKTNIGCQSYMAPERIRVGGPTNGVLTYTV 500
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDY 324
Q+D+WSLGL+++EMA+G YP PP ++ +IF +L
Sbjct: 501 QADVWSLGLTILEMALGAYPYPP---ESYTSIFA---------------------QLSAI 536
Query: 325 IVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGW 382
+PP LP FS E +DFV++CL KNP R D L NH W+ K + VD+A W
Sbjct: 537 CDGDPP-SLPDS-FSPEARDFVNKCLNKNPSLRPDYHELANHPWLLKYQNADVDMASW 592
>UniRef50_Q876Z4 Cluster: Putative PBS2 like MAPK kinase; n=1;
Neurospora crassa|Rep: Putative PBS2 like MAPK kinase -
Neurospora crassa
Length = 637
Score = 231 bits (566), Expect = 2e-59
Identities = 130/297 (43%), Positives = 177/297 (59%), Gaps = 41/297 (13%)
Query: 85 LSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN 144
+S D+ E + ELG+GN G V KVRH +MA K I LE+ + I++EL +LHEC
Sbjct: 286 ISLDEVEVMDELGKGNYGTVYKVRHSK---VMAMKEIRLELDESKFSTILKELVILHECA 342
Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRD 204
+I+ FYGAFY +G + +C+EYMDGGS+D + AG IPE++L IT A + GL L++
Sbjct: 343 SPYIIDFYGAFYQEGAVYMCIEYMDGGSIDKLY--AGGIPENVLRKITYATIMGLKCLKE 400
Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQG----- 259
H I+HRDVKP+NILVN+NG++KICDFGVSG L+ S+A + +G +SYM+PER+ G
Sbjct: 401 DHNIIHRDVKPTNILVNTNGQVKICDFGVSGNLVASIAKTNIGCQSYMAPERISGGGMSA 460
Query: 260 ------THYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
YSVQSDIWSLGL+++E A+G YP PP + T+ + E PG
Sbjct: 461 AGGAAAGTYSVQSDIWSLGLTIIECAMGRYPYPPEVSSTIFSQLSAIVEGDPPG------ 514
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370
LPS +S +DFV CL K P +R L+ H WI+
Sbjct: 515 -------------------LPSEGYSGTAQDFVKSCLNKIPAKRHTYPMLLMHPWIK 552
>UniRef50_Q5KN75 Cluster: MAP kinase kinase, putative; n=1;
Filobasidiella neoformans|Rep: MAP kinase kinase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 609
Score = 229 bits (560), Expect = 1e-58
Identities = 133/321 (41%), Positives = 186/321 (57%), Gaps = 47/321 (14%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
+++ D+ E LGELG+GN G V KV H+ TG+ MA K I LE+ + II EL +LH
Sbjct: 289 KINMDEIEVLGELGKGNYGSVHKVFHRPTGVTMAMKEIRLELDDSKLNGIIMELDILHRA 348
Query: 144 NFAHIVGFYGAFYSDGEISICMEYMDGGSLDLIL---------------KKAGRIPESIL 188
IV FYGAF + + CMEYMD GSLD + R+PE +L
Sbjct: 349 VAPEIVEFYGAFTIESCVYYCMEYMDAGSLDSLTGGGVAAKDQTKEEEDDATERVPEDVL 408
Query: 189 GTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGT 248
IT+ ++KGL +L+D+ I+HRDVKP+N+L+N GE+K+CDFGVSGQL S+A + +G
Sbjct: 409 RRITARIVKGLRFLKDELQIIHRDVKPTNVLINGKGEVKMCDFGVSGQLEKSLAKTNIGC 468
Query: 249 RSYMSPERL------QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNE 302
+SYM+PER+ Q Y+V SD+WS+GLS+VE+A G YP PP +T A +F
Sbjct: 469 QSYMAPERIKSETANQNPTYTVSSDVWSVGLSIVELAKGCYPYPP---ETYANVFA---- 521
Query: 303 DHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKT 362
L IV+ PP LP G +SD+ DFV +CL+K+P+ R
Sbjct: 522 ------------------QLQAIVHGTPPTLPPG-YSDDANDFVAKCLEKDPNRRPTYAQ 562
Query: 363 LMNHEWIRKAEAEKVDIAGWV 383
L+ H ++ + +VD+ GWV
Sbjct: 563 LLEHPFLVADKGAEVDMVGWV 583
>UniRef50_Q9Y884 Cluster: MAP kinase kinase skh1/pek1; n=1;
Schizosaccharomyces pombe|Rep: MAP kinase kinase
skh1/pek1 - Schizosaccharomyces pombe (Fission yeast)
Length = 363
Score = 226 bits (553), Expect = 7e-58
Identities = 127/296 (42%), Positives = 176/296 (59%), Gaps = 33/296 (11%)
Query: 93 LGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFY 152
+ LG+G G V K R + T +I A K + A++KQ++RELK+ C +IV +Y
Sbjct: 82 MNSLGEGVSGSVRKCRIRGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCTSPYIVKYY 141
Query: 153 GAFYSDGE--ISICMEYMDGGSLDLILKKA----GRIPESILGTITSAVLKGLSYLRDKH 206
GA Y++ E ++I MEY GSLD I K+ GR E LG I VL GLSYL D+
Sbjct: 142 GACYNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLSGLSYLHDRK 201
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQS 266
I+HRD+KPSNIL+ S G++K+CDFGVSG+L++S+A +F GT YM+PER+ G Y++ S
Sbjct: 202 -IIHRDIKPSNILLTSKGQVKLCDFGVSGELVNSLAGTFTGTSYYMAPERISGGSYTISS 260
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
DIWSLGL+L+E+A+ +P PP SP PM I ELL YI+
Sbjct: 261 DIWSLGLTLMEVALNRFPFPP----------------------EGSPPPMPI-ELLSYII 297
Query: 327 NEPPPKLPS--GI-FSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDI 379
N PPP LP GI +S F+ F+ CL K+ R + ++ H W++ E VD+
Sbjct: 298 NMPPPLLPQEPGIKWSKSFQHFLCVCLDKDKTRRPGPQKMLTHPWVKAFERIHVDM 353
>UniRef50_Q5KGY3 Cluster: Mitogen-activated protein kinase kinase,
putative; n=2; Filobasidiella neoformans|Rep:
Mitogen-activated protein kinase kinase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 621
Score = 223 bits (546), Expect = 5e-57
Identities = 126/299 (42%), Positives = 185/299 (61%), Gaps = 34/299 (11%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
LG+G GG V V+ ++TG IMA+K+I P + KQ++REL++L+ C IV YG+F
Sbjct: 337 LGEGTGGSVDMVQDRATGRIMAKKVITRTSNPMVHKQLLRELEILNSCASPFIVEHYGSF 396
Query: 156 YSDGE--ISICMEYMDGGSLDLIL----KKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+D + I I MEY + GSLD +L KK+ R E +LG + S+VLKGL YL + I+
Sbjct: 397 LADHDSSIGILMEYCEAGSLDSLLGKMKKKSMRCSEHVLGRVASSVLKGLDYLHQRR-IV 455
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIW 269
HRD+KPSNIL+ G +K+CDFGVSG+L++S+A +F GT YM+PER+Q YS+++D+W
Sbjct: 456 HRDIKPSNILITRQGAVKLCDFGVSGELVESLAGTFTGTSFYMAPERIQNKPYSIKADVW 515
Query: 270 SLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEP 329
SLG++L E+A +P PP G+N+ +P ELL YIV P
Sbjct: 516 SLGMTLHEIAHLRFPFPPE----------GENQSVAP------------IELLSYIVTAP 553
Query: 330 PP----KLPSG-IFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGWV 383
P L G ++S+ KDF+ +CL ++ +R L+ H +I +EA+KV++A WV
Sbjct: 554 VPVMIDDLSVGRVWSEPIKDFMGQCLIRSGTDRPYPWQLLQHPFIVASEAKKVNMAKWV 612
>UniRef50_Q75BS5 Cluster: ACR196Cp; n=2; Saccharomycetaceae|Rep:
ACR196Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 530
Score = 222 bits (543), Expect = 1e-56
Identities = 134/325 (41%), Positives = 191/325 (58%), Gaps = 46/325 (14%)
Query: 67 TQRRRIEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVK 126
T+ R+ +F ++ ++ +D +LG++G GN G V+K H I+A+K I +E
Sbjct: 175 TKFSRLSIF---QDDNNDIQLEDLVQLGKIGAGNSGTVVKTLHVPDSRIIAKKSIPVENS 231
Query: 127 PAIKKQIIRELKVLHEC-NFAHIVGFYGAFYS---DGEISICMEYMDGGSLDLILK---- 178
+K Q++REL ++ +IVGFYGA+Y+ + EI I MEYMD GSLD I
Sbjct: 232 ELVKNQLMRELTIMKNVKEQKNIVGFYGAYYTAIKNHEIIILMEYMDCGSLDKISSTYRR 291
Query: 179 --KAGRIP---------ESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIK 227
++P E L I+ AVL GLSYL + I+HRD+KPSNIL+NS G +K
Sbjct: 292 YCSRNKVPMNASTSWFTELSLSKISYAVLNGLSYLYQDYKIIHRDIKPSNILINSKGFVK 351
Query: 228 ICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPP 287
ICDFGVS ++IDS+A++FVGT +YMSPER+QG+ Y+ + D+WSLGL ++E+ G +P+
Sbjct: 352 ICDFGVSKKMIDSIADTFVGTSTYMSPERIQGSCYNTKGDVWSLGLMIIELVTGEFPL-- 409
Query: 288 PDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLP-SGIFSDEFKDFV 346
GG N+ P I +LL IVNE PP LP SG FS + DFV
Sbjct: 410 ----------GGHND-----------TPEGILDLLQRIVNEEPPSLPASGDFSADIMDFV 448
Query: 347 DRCLKKNPDERADLKTLMNHEWIRK 371
+ C K+ +R+ L+ LM H +I K
Sbjct: 449 NCCCVKDERKRSSLQELMTHRYITK 473
>UniRef50_Q6BLD0 Cluster: Similar to ca|CA1623|CaSTE7 Candida
albicans CaSTE7 MAP Kinase Kinase; n=2;
Saccharomycetaceae|Rep: Similar to ca|CA1623|CaSTE7
Candida albicans CaSTE7 MAP Kinase Kinase - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 504
Score = 220 bits (538), Expect = 5e-56
Identities = 128/294 (43%), Positives = 177/294 (60%), Gaps = 30/294 (10%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
+L+++D L LG GN G V K+ H T MA+K+IH+++K I+ QIIREL++LHEC
Sbjct: 194 KLNNNDLLTLKNLGSGNSGTVSKILHIPTQKTMAKKIIHIDLKSVIQTQIIRELRILHEC 253
Query: 144 NFAHIVGFYGAFYSDGE-ISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLS 200
I+ FYGAF ++ I ICMEY + GSLD IL + + P +L ++ A+L GL+
Sbjct: 254 QSPFIIEFYGAFINNNNTIVICMEYCNCGSLDKILPLCQNNQFPLFVLKKLSYAILSGLT 313
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQ 258
YL H I+HRD+KPSN+L+N GE K+CDFGV +L +S MA++FVGT +YMSPER+Q
Sbjct: 314 YLYSTHKIIHRDIKPSNVLMNHKGEFKLCDFGVLRELTNSLAMADTFVGTSTYMSPERIQ 373
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
G Y V+SD+WS+GL L+E+A G IP ++ E+ P Q P I
Sbjct: 374 GLTYGVKSDVWSMGLMLIELARG---IP---------VWVDDGEEEGP-QGPE-----GI 415
Query: 319 FELLDYIVNEPPPKLPSGI-------FSDEFKDFVDRCLKKNPDERADLKTLMN 365
+LL IVNE PP L + F D F+D CL K+ + R L+N
Sbjct: 416 LDLLQRIVNEAPPSLANKTNTTTNQPFDDILCKFIDSCLIKDDNLRKSPWDLLN 469
>UniRef50_P32490 Cluster: MAP kinase kinase MKK1/SSP32; n=8;
Saccharomycetales|Rep: MAP kinase kinase MKK1/SSP32 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 508
Score = 220 bits (538), Expect = 5e-56
Identities = 130/305 (42%), Positives = 178/305 (58%), Gaps = 26/305 (8%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH-LEVKPAIKKQIIRELKVLHECNFA 146
D E LG LG+G GG V K + K+ I A K+I+ L P +KQI REL+
Sbjct: 219 DRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSE 278
Query: 147 HIVGFYGAFYSD--GEISICMEYMDGGSLDLI----LKKAGRIPESILGTITSAVLKGLS 200
+IV +YG F D I I MEYM G SLD I L++ GRI E +LG I AVL+GLS
Sbjct: 279 YIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLS 338
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGT 260
YL +K I HRD+KP NIL+N NG++K+CDFGVSG+ ++S+A +F GT YM+PER+QG
Sbjct: 339 YLHEKKVI-HRDIKPQNILLNENGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQ 397
Query: 261 HYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFE 320
YSV SD+WSLGL+++E+A G +P +E + AP M I
Sbjct: 398 PYSVTSDVWSLGLTILEVANGKFPC--------------SSEKMAANIAP-FELLMWILT 442
Query: 321 LLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIA 380
+ +EP + I+S FK F+D CLKK+ ER + ++NH WI+ + V++
Sbjct: 443 FTPELKDEPESNI---IWSPSFKSFIDYCLKKDSRERPSPRQMINHPWIKGQMKKNVNME 499
Query: 381 GWVCK 385
+V K
Sbjct: 500 KFVRK 504
>UniRef50_A2RAN1 Cluster: Contig An18c0110, complete genome; n=19;
Pezizomycotina|Rep: Contig An18c0110, complete genome -
Aspergillus niger
Length = 542
Score = 220 bits (537), Expect = 6e-56
Identities = 133/373 (35%), Positives = 206/373 (55%), Gaps = 37/373 (9%)
Query: 26 PSNMTPQLKSATA---NERQGLAGKSKTSIEALTERLEQIEMDDTQRRRIEVFLCQKEKI 82
P TP SA + + G+ + +S+ +L L+++ ++ + ++ L + +
Sbjct: 151 PHGSTPDPSSAISVYSDRESGVQMERDSSVNSLIPDLDKMSLEKGRPLDVDD-LDDEAWL 209
Query: 83 GELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE 142
+LG LG+G GG V + + K + A K+I + P +KKQI+REL +
Sbjct: 210 AASEQKKIVELGSLGEGAGGAVTRCKLKEGKTVFALKIITTDPNPDVKKQIVRELNFNKD 269
Query: 143 CNFAHIVGFYGAFY--SDGEISICMEYMDGGSLDLILKKA----GRIPESILGTITSAVL 196
C HI +YGAF S G ISI ME+ +GGSLD I K+ GR E +LG + VL
Sbjct: 270 CASEHICRYYGAFMDKSTGTISIAMEFCEGGSLDSIYKEVKKLGGRTGEKVLGKVAEGVL 329
Query: 197 KGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL-IDSMANSFVGTRSYMSPE 255
GL+YL + I+HRD+KPSNIL+ NG++K+CDFGVSG+ AN+F+GT YM+PE
Sbjct: 330 NGLTYLHSRK-IIHRDIKPSNILLCRNGQVKLCDFGVSGEFGTKGDANTFIGTSYYMAPE 388
Query: 256 RLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRP 315
R+ G Y++ SD+WSLG++L+E+A +P P + PR
Sbjct: 389 RITGQSYTITSDVWSLGVTLLEVAQHRFPFPADGTEM-------------------QPR- 428
Query: 316 MAIFELLDYIVNEPPPKL----PSGI-FSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370
+ +LL YIV +P PKL +GI +S+ FK F++ CL+K P RA ++ H W+
Sbjct: 429 AGLIDLLTYIVRQPIPKLKDEPDNGIRWSENFKYFIECCLEKEPPRRATPWRMLEHPWML 488
Query: 371 KAEAEKVDIAGWV 383
+ +KV++A ++
Sbjct: 489 DMKNKKVNMANFI 501
>UniRef50_A0CZB0 Cluster: Chromosome undetermined scaffold_32, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_32,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 377
Score = 219 bits (534), Expect = 1e-55
Identities = 123/322 (38%), Positives = 191/322 (59%), Gaps = 24/322 (7%)
Query: 65 DDTQRRRIEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE 124
+D +++ + Q E+ ++ D + +LGQG+ G V+K H+ T L++A K I +
Sbjct: 73 EDPKKKLQQQHQFQNERY-QIQLQDLISIDDLGQGSSGRVIKALHRPTNLLVALKTIQVV 131
Query: 125 VKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIP 184
KQI EL+ L C+ ++I+ YGAF +++I +E+M+ G+L ++KK+G+IP
Sbjct: 132 NDEKFTKQINLELETLVSCDHSNIIRCYGAFLEGAQVAIALEFMNLGTLQDVIKKSGKIP 191
Query: 185 ESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MA 242
E +LG I +LKGL YL I+HRD+KPSN+L+NS GE+KI DFGVSGQL+++
Sbjct: 192 EGMLGLIAYQLLKGLDYLHRTKKIIHRDIKPSNLLINSAGEVKISDFGVSGQLLNTQDQR 251
Query: 243 NSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNE 302
+++VGT +YMSPER YS +D+WSLGLSL+E A G++P P P G NE
Sbjct: 252 STWVGTVTYMSPERFLCEPYSSNTDVWSLGLSLLECAWGVFPYPHP----------GTNE 301
Query: 303 DHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKT 362
+P + +E+ +YIV+ P P P FS DF+ CL+K+P +R
Sbjct: 302 --------TTP-SLGFWEIKEYIVSRPAPPSPPE-FSQMGADFIAMCLQKDPRKRRSAAE 351
Query: 363 LMNHEWIRKAEAEKVD-IAGWV 383
L+ H +I++ E + + GW+
Sbjct: 352 LLEHPFIKQYEDVSLQYLEGWL 373
>UniRef50_UPI000023D36E Cluster: hypothetical protein FG08691.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08691.1 - Gibberella zeae PH-1
Length = 647
Score = 217 bits (531), Expect = 3e-55
Identities = 117/269 (43%), Positives = 162/269 (60%), Gaps = 37/269 (13%)
Query: 111 STGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDG 170
+TG +MA K + LE+ A I++EL +LHEC +I+ FYGAF+ +G + +C+EYMDG
Sbjct: 324 TTGTVMAMKEMRLELDDAKFTTILKELVILHECVSPYIIEFYGAFFQEGAVYMCIEYMDG 383
Query: 171 GSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICD 230
GS+D + AG IPE++L IT + + GL L+D+H+I+HRDVKP+NILVN+ G++KICD
Sbjct: 384 GSIDKLY--AGGIPENVLRKITYSTVMGLKSLKDEHSIIHRDVKPTNILVNTRGQVKICD 441
Query: 231 FGVSGQLIDSMANSFVGTRSYMSPERLQG----------THYSVQSDIWSLGLSLVEMAI 280
FGVSG L+ S+A + +G +SYM+PER+ G YSVQSD+WSLGL+++E A
Sbjct: 442 FGVSGNLVASIARTNIGCQSYMAPERISGGGYAQAGNSDGSYSVQSDVWSLGLTVIECAK 501
Query: 281 GMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSD 340
G YP PP + T IF L IV PP +P +SD
Sbjct: 502 GAYPYPPEVSST-------------------------IFSQLSAIVEGEPPAMPEEGYSD 536
Query: 341 EFKDFVDRCLKKNPDERADLKTLMNHEWI 369
DFV CL K P +R L+ H W+
Sbjct: 537 TATDFVRSCLHKIPKQRPTYAMLLKHPWL 565
>UniRef50_Q9P8J0 Cluster: Map kinase kinase; n=1; Pneumocystis
carinii|Rep: Map kinase kinase - Pneumocystis carinii
Length = 398
Score = 214 bits (522), Expect = 4e-54
Identities = 120/308 (38%), Positives = 183/308 (59%), Gaps = 26/308 (8%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
D+ +L +LG+G G V K K+TG + A K I ++ P I++QI+REL + C+ +
Sbjct: 109 DEIIELEKLGEGISGSVSKCILKNTGTLFALKTILVDTNPEIQQQILRELSINRTCSSEY 168
Query: 148 IVGFYGAFYSDGE--ISICMEYMDGGSLDLILKKA----GRIPESILGTITSAVLKGLSY 201
IV +YG F + IS+ MEY GGSLD + KK RI E + I LKGL+Y
Sbjct: 169 IVQYYGTFVDEASSNISMAMEYCAGGSLDRLYKKVRANGARIGEYPILKIAENALKGLNY 228
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH 261
L + I+HRD+KPSNIL+ G+ K+CDFGVSG+L+ SMA +F GT YM+PER++G
Sbjct: 229 LHTRK-IIHRDIKPSNILMTLEGQAKLCDFGVSGELVSSMAKTFTGTSYYMAPERIKGET 287
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
YS+ SDIWSLGL+L+E++ +P PP + P + N ++ FEL
Sbjct: 288 YSITSDIWSLGLTLMEISQNRFPFPPEGPPLV------------PIELLNYIVNISNFEL 335
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAG 381
+D EP K+ +S++FK F+ CL+++ +R + + ++ H W+ K K+D+A
Sbjct: 336 VD----EPDNKIK---WSEDFKHFLKTCLERDGAKRPNSQRMLEHPWVMKHSIIKIDMAK 388
Query: 382 WVCKTMDL 389
W+ + ++L
Sbjct: 389 WIKQILEL 396
>UniRef50_Q6BTT8 Cluster: Similar to CA4577|CaMKK2 Candida albicans;
n=2; Saccharomycetaceae|Rep: Similar to CA4577|CaMKK2
Candida albicans - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 426
Score = 213 bits (519), Expect = 9e-54
Identities = 139/369 (37%), Positives = 202/369 (54%), Gaps = 42/369 (11%)
Query: 15 PGSIDTNPAA-TPSNMTPQLKSATANER-QGLAGKSKTSIEALTERLEQIEMDDTQRRRI 72
P +I NP++ T S + N R + +K + E + +D ++R+
Sbjct: 62 PDTISPNPSSGTHSGIQSATSDILENLRAHNIGNNTKQNNEQCKNNEQSKNNNDEIQKRV 121
Query: 73 EVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQ 132
E L + +D+ +L +LG+GNGG V K + I A KLI+ + P I+KQ
Sbjct: 122 ED-LSPDDWNRLANDNQIIELNKLGEGNGGSVSKCTLVNGSQIFALKLINADPNPNIQKQ 180
Query: 133 IIRELKVLHECNFAHIVGFYGAFYSDGE--ISICMEYMDGGSLDLILKKA------GRIP 184
IIREL+ C+ +IV +YG F + + I I MEYM G SLD I K+ RI
Sbjct: 181 IIRELQYNRVCDSPNIVKYYGTFMVEKQLMIGISMEYMGGRSLDAIYKRVIELDPTNRIN 240
Query: 185 ESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS 244
E +LG + ++L GL+YL + I+HRD+KPSNIL++S G IK+CDFGVSG++++S+A +
Sbjct: 241 EKVLGKVAESILTGLNYLHQQR-IIHRDIKPSNILLDSEGNIKLCDFGVSGEVVNSLATT 299
Query: 245 FVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDH 304
FVGT+ YM+PER+ G Y+V DIWSLGL+L+E+AI +P D
Sbjct: 300 FVGTQYYMAPERIMGKPYTVSCDIWSLGLTLLEVAICKFPFITDDTM------------- 346
Query: 305 SPGQAPNSPRPMAIFELLDYIVNEPPPKL----PSGIF-SDEFKDFVDRCLKKNPDERAD 359
+ ELL I+ E PKL GIF SD FK+F+ CLKKN +ER
Sbjct: 347 -----------VGPIELLSLIL-EYEPKLNDIPEQGIFWSDSFKNFIGYCLKKNSEERPS 394
Query: 360 LKTLMNHEW 368
+ +++H W
Sbjct: 395 PRQMLSHPW 403
>UniRef50_Q24D49 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 2001
Score = 212 bits (518), Expect = 1e-53
Identities = 117/317 (36%), Positives = 183/317 (57%), Gaps = 23/317 (7%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148
+ ++ LG G+ G+V H +TG+++ K I L + + +KQ+ +ELK L +C I
Sbjct: 281 ELRRVKVLGHGSSGLVELAVHDATGIVIGIKSIPLLMNSSFRKQLDQELKTLIQCESDSI 340
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
V YGA+ I+I +EYMD G++ ++KK G +PE I+ + VLKGL Y+ +K +
Sbjct: 341 VKCYGAYIQKCMINITLEYMDLGTVHDLVKKVGPLPEIIVAIMAIQVLKGLDYIHNKAKV 400
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM-ANSFVGTRSYMSPERLQGTHYSVQSD 267
+HRD+KPSN+LVNS G++KI DFGVS L ++ ++VGT +YMSPER +G Y+ +D
Sbjct: 401 IHRDIKPSNLLVNSKGQVKIADFGVSANLESAVEVKNWVGTVTYMSPERFRGQAYTANTD 460
Query: 268 IWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVN 327
IWSLGL++ E A+G YP F + ++ +ELL+Y
Sbjct: 461 IWSLGLTICECALGTYP-----------YFDSNQYEKKEN--------LSFWELLEYFNM 501
Query: 328 EPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK-AEAEKVDIAGWVCKT 386
+P P+LP +S+E KDFV +C KK+P +R L+NHE ++K ++ + W+ K
Sbjct: 502 KPAPRLPEN-YSEEMKDFVAKCFKKSPLDRPHSHDLLNHEMVKKFSQYDSSYFEEWITKN 560
Query: 387 MDLMPSTPNSNVSPFSS 403
+L P+ +P S
Sbjct: 561 -NLKPAQDKYEPAPVVS 576
>UniRef50_A6QXW3 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 668
Score = 212 bits (518), Expect = 1e-53
Identities = 118/266 (44%), Positives = 158/266 (59%), Gaps = 34/266 (12%)
Query: 111 STGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDG 170
++ +IMA K I LE+ A II EL +LH C I+ FYGAF+ +G + IC+EYMDG
Sbjct: 328 TSNVIMAMKEIRLELDEAKFTAIIMELDILHRCVSPFIIDFYGAFFQEGAVYICVEYMDG 387
Query: 171 GSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICD 230
GS++ + IPE+IL IT + + GL L+D+H I+HRDVKP+NIL+N+ G+IKICD
Sbjct: 388 GSVEKVYGDG--IPENILRKITLSTIMGLKSLKDEHNIIHRDVKPTNILMNTRGQIKICD 445
Query: 231 FGVSGQLIDSMANSFVGTRSYMSPERLQ-------GTHYSVQSDIWSLGLSLVEMAIGMY 283
FGVSG L+ S+A + +G +SYM+PER+ G YSVQSDIWSLGL++VE A+G Y
Sbjct: 446 FGVSGNLVASIAKTNIGCQSYMAPERIAGGGGTAGGGTYSVQSDIWSLGLTVVECAMGRY 505
Query: 284 PIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFK 343
P PP + F L+ IV+ PPKLP +S E K
Sbjct: 506 PYPPETFNNI-------------------------FSQLNAIVHGDPPKLPEHGYSPEAK 540
Query: 344 DFVDRCLKKNPDERADLKTLMNHEWI 369
DFV RCL K+ R L+ W+
Sbjct: 541 DFVQRCLNKDASRRPTYSMLLRDPWL 566
>UniRef50_A1D1G2 Cluster: MAP kinase kinase (Pbs2), putative; n=8;
Trichocomaceae|Rep: MAP kinase kinase (Pbs2), putative -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 656
Score = 212 bits (517), Expect = 2e-53
Identities = 119/275 (43%), Positives = 157/275 (57%), Gaps = 38/275 (13%)
Query: 106 KVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICM 165
K + +G IMA K I LE+ QII EL +LH C I+ FYGAF+ +G + +C+
Sbjct: 322 KPQDNLSGYIMAMKEIRLELDENKFAQIIMELDILHRCVSPFIIDFYGAFFQEGAVYMCV 381
Query: 166 EYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGE 225
EYMDGGS+D + K +PE+IL + + + GL L+D H I+HRDVKP+NILVNS G+
Sbjct: 382 EYMDGGSIDKLYKDG--VPENILRKVALSTVMGLKTLKDDHNIIHRDVKPTNILVNSRGQ 439
Query: 226 IKICDFGVSGQLIDSMANSFVGTRSYMSPERLQ-----------GTHYSVQSDIWSLGLS 274
IKICDFGVSG L+ S+A + +G +SYM+PER+ G YSVQSDIWSLGL+
Sbjct: 440 IKICDFGVSGNLVASIAKTNIGCQSYMAPERIAGGGVQQSGATGGGTYSVQSDIWSLGLT 499
Query: 275 LVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLP 334
++E AIG YP PP + F L IV+ PP LP
Sbjct: 500 IIECAIGRYPYPPETFNNI-------------------------FSQLHAIVHGDPPTLP 534
Query: 335 SGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
+S+E FV CL K P +R TL+ H W+
Sbjct: 535 EQGYSEEAHAFVRACLDKTPSKRPSYSTLLRHPWL 569
Score = 34.3 bits (75), Expect = 5.8
Identities = 15/25 (60%), Positives = 19/25 (76%)
Query: 85 LSDDDFEKLGELGQGNGGVVMKVRH 109
+S D+ E+L ELG+GN G V KVRH
Sbjct: 266 ISLDEVERLDELGKGNYGTVYKVRH 290
>UniRef50_P06784 Cluster: Serine/threonine-protein kinase STE7; n=2;
Saccharomyces cerevisiae|Rep: Serine/threonine-protein
kinase STE7 - Saccharomyces cerevisiae (Baker's yeast)
Length = 515
Score = 212 bits (517), Expect = 2e-53
Identities = 125/302 (41%), Positives = 179/302 (59%), Gaps = 42/302 (13%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPA-IKKQIIRELKVLHECN-FA 146
D +LG++G GN G V+K H I+A+K I +E + I Q++REL ++
Sbjct: 190 DLVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHE 249
Query: 147 HIVGFYGAFYS---DGEISICMEYMDGGSLDLILK------KAGRIP-------ESILGT 190
+I+ FYGA+Y+ + EI I MEY D GSLD IL + G + E +
Sbjct: 250 NIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISK 309
Query: 191 ITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRS 250
I VL GL +L ++ I+HRD+KPSN+L+NS G+IK+CDFGVS +LI+S+A++FVGT +
Sbjct: 310 IAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTST 369
Query: 251 YMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAP 310
YMSPER+QG YS++ D+WSLGL ++E+ G +P+ GG N+
Sbjct: 370 YMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPL------------GGHND-------- 409
Query: 311 NSPRPMAIFELLDYIVNEPPPKLPSG-IFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
P I +LL IVNEP P+LP I+S E DFV+RC KN ER+ + L++H+ I
Sbjct: 410 ---TPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLI 466
Query: 370 RK 371
K
Sbjct: 467 MK 468
>UniRef50_Q6CET2 Cluster: Similar to sp|P32490 Saccharomyces
cerevisiae YOR231w MKK1 ser/thr protein kinase; n=1;
Yarrowia lipolytica|Rep: Similar to sp|P32490
Saccharomyces cerevisiae YOR231w MKK1 ser/thr protein
kinase - Yarrowia lipolytica (Candida lipolytica)
Length = 522
Score = 211 bits (516), Expect = 2e-53
Identities = 118/289 (40%), Positives = 171/289 (59%), Gaps = 31/289 (10%)
Query: 92 KLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGF 151
+LG+LG+G GG V R ++ + A K I P ++KQI+REL+ C+ HIV +
Sbjct: 235 ELGKLGEGAGGSVTLCRLRTGSTVFALKSITANPNPELQKQIVRELRFNRTCSSPHIVKY 294
Query: 152 YGAFYSD--GEISICMEYMDGGSLDLILKKA----GRIPESILGTITSAVLKGLSYLRDK 205
YG F +D I I MEY GGSLD I K+ GRI E +LG + VLKGLSYL ++
Sbjct: 295 YGTFLNDEAASIFIAMEYCGGGSLDAIYKRVKDRGGRIGEKVLGKVAEGVLKGLSYLHER 354
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQ 265
I+HRD+KP NIL++ G++K+CDFGVSG++++S+A +F GT YM+PER+ G YSV
Sbjct: 355 R-IIHRDIKPQNILLDKEGQVKLCDFGVSGEVVNSLATTFTGTSYYMAPERILGQPYSVT 413
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYI 325
SD+WSLGL+++E+A +P + E P+ ELL I
Sbjct: 414 SDVWSLGLTIMEVAQHRFP-----------FISAEQEARE--------EPITPIELLSII 454
Query: 326 VNEPPPKL----PSGI-FSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
VN P P+L GI +S+ F+ F+ CL+K+ +RA + ++ H W+
Sbjct: 455 VNAPAPELKDEPEEGIKWSNAFRHFLLCCLEKDQSKRASPRQMLKHPWM 503
>UniRef50_A1DYH9 Cluster: MAP kinase kinase PBS2 isoform B1; n=9;
Pezizomycotina|Rep: MAP kinase kinase PBS2 isoform B1 -
Hortaea werneckii
Length = 696
Score = 211 bits (515), Expect = 3e-53
Identities = 125/302 (41%), Positives = 174/302 (57%), Gaps = 42/302 (13%)
Query: 79 KEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELK 138
K + GE + + K G L GN K +TG++MA K + LE+ A + II EL
Sbjct: 323 KPRPGEQKESEESKDGPL-IGNVSASGK---GTTGVVMAMKEMRLELDDAKFQSIIMELD 378
Query: 139 VLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKG 198
+LH C +IV FYGAF+ +G + ICME+MDGGS+D + +PE++L +T A G
Sbjct: 379 ILHRCVSPYIVDFYGAFFQEGAVYICMEFMDGGSMDKLYGDG--VPENVLRKVTFATTMG 436
Query: 199 LSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQ 258
L L+++H I+HRDVKP+NILVN+ G++KICDFGVSG L+ S+A + +G +SYM+PER+
Sbjct: 437 LKSLKEEHNIIHRDVKPTNILVNTKGQVKICDFGVSGNLVASIAKTNIGCQSYMAPERIS 496
Query: 259 -----------GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPG 307
G YSVQSDIWSLGL+++E A+G YP PP + D+
Sbjct: 497 SGGMASAGADAGGTYSVQSDIWSLGLTIIECALGRYPYPP------------ETYDN--- 541
Query: 308 QAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHE 367
IF L IV+ PP LPS +S+ ++FV CL K P R L+ H
Sbjct: 542 ----------IFSQLSAIVDGEPPDLPSERYSEAARNFVAGCLNKIPKLRPTYPMLLQHA 591
Query: 368 WI 369
W+
Sbjct: 592 WL 593
>UniRef50_O00885 Cluster: MAP kinase kinase protein DdMEK1; n=3;
Eukaryota|Rep: MAP kinase kinase protein DdMEK1 -
Dictyostelium discoideum (Slime mold)
Length = 660
Score = 210 bits (513), Expect = 5e-53
Identities = 105/198 (53%), Positives = 141/198 (71%), Gaps = 2/198 (1%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148
D + + LG+G GGVV H+++G +A K+I L+++ I+KQII ELK LH+ ++ +I
Sbjct: 291 DLKIIRVLGRGAGGVVKLAYHETSGTYIALKVITLDIQENIRKQIILELKTLHKTSYPYI 350
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
V FY AFY++G I I +E+M+ GSL I+KK IPE +LG I VL+GL YL K +
Sbjct: 351 VSFYDAFYTEGSIFIALEFMELGSLSDIMKKTSTIPEPVLGKIAFQVLQGLVYLHRKLHL 410
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTHYSVQS 266
+HRD+KPSNILVN+ GE KI DFGVSGQL S A ++VGT +YMSPER+ G YS S
Sbjct: 411 IHRDIKPSNILVNNKGEAKIADFGVSGQLQHTLSKAVTWVGTVTYMSPERISGRSYSFDS 470
Query: 267 DIWSLGLSLVEMAIGMYP 284
DIWSLGL+++E AIG +P
Sbjct: 471 DIWSLGLTILECAIGKFP 488
Score = 59.7 bits (138), Expect = 1e-07
Identities = 29/66 (43%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Query: 313 PRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
P M + LLD IV E P LPS FS EF+ F+ CL+K P ER L+NHE+++K
Sbjct: 586 PEGMGFWVLLDCIVKEEVPILPS-TFSKEFRSFISECLQKEPTERPTASNLLNHEFVKKY 644
Query: 373 EAEKVD 378
+ V+
Sbjct: 645 QNFNVE 650
>UniRef50_A7TL15 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 538
Score = 208 bits (509), Expect = 2e-52
Identities = 131/322 (40%), Positives = 188/322 (58%), Gaps = 52/322 (16%)
Query: 92 KLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVK-PAIKKQIIRELKVLHECNFAH--I 148
+LG++G GN G V+K H I+A+K I +E + Q++REL ++ AH I
Sbjct: 207 QLGKIGSGNSGTVIKALHVPDSRIIAKKTIPVETNNELVINQLLRELTIMRSVK-AHPNI 265
Query: 149 VGFYGAFY---SDGEISICMEYMDGGSLDLILK---------KAGR----IPESILGTIT 192
V FYGA+Y S+ E+ I +EYM+ GSLD IL KA E + I+
Sbjct: 266 VEFYGAYYDQSSNNELVILLEYMNCGSLDKILSVHKAFCQRNKASPDKSWFNELAISKIS 325
Query: 193 SAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYM 252
AVL LSYL + I+HRD+KPSN+L+NS G++KICDFGVS ++++S+A++FVGT +YM
Sbjct: 326 YAVLTSLSYLYKNYKIIHRDIKPSNVLINSKGQVKICDFGVSKKMVNSIADTFVGTSTYM 385
Query: 253 SPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNS 312
SPER+QG YS + D+WSLGL ++E+ G +P+ GG N+
Sbjct: 386 SPERIQGNVYSTKGDVWSLGLMIIELVTGEFPL------------GGIND---------- 423
Query: 313 PRPMAIFELLDYIVNEPPPKLPSGI----FSDEFKDFVDRCLKKNPDERADLKTLMNHEW 368
P I +LL IVNEP P+LPS + + E DFV+RC KN ER+ ++ L+ H++
Sbjct: 424 -TPDGILDLLQRIVNEPSPRLPSNLDETRYKREITDFVNRCCVKNERERSSIEELLCHDF 482
Query: 369 IRK---AEAEKVDIAGWVCKTM 387
+ K AE +K + W CK M
Sbjct: 483 VTKYSSAENDK-EFKHW-CKKM 502
>UniRef50_A7TKP9 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 526
Score = 208 bits (509), Expect = 2e-52
Identities = 125/305 (40%), Positives = 172/305 (56%), Gaps = 26/305 (8%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH-LEVKPAIKKQIIRELKVLHECNFA 146
D+ LG LG+G GG V K + KS I A K I+ L P +KQI REL+
Sbjct: 234 DEIVTLGLLGEGAGGSVAKCKLKSGSKIFALKTINTLNTDPEYQKQIFRELQFNKSFKSD 293
Query: 147 HIVGFYGAFY--SDGEISICMEYMDGGSLDLI----LKKAGRIPESILGTITSAVLKGLS 200
+IV +YG F S+ I I MEYM G SLD I L GRI E +LG I +VL+GLS
Sbjct: 294 YIVRYYGMFTDESNSSIFIAMEYMGGRSLDAIYLNLLNLGGRIGEKVLGKIAESVLRGLS 353
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGT 260
YL ++ I HRD+KP NIL+N G++K+CDFGVSG+ ++S+A +F GT YM+PER+QG
Sbjct: 354 YLHERKVI-HRDIKPQNILLNEKGQVKLCDFGVSGEAVNSLATTFTGTSFYMAPERIQGQ 412
Query: 261 HYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFE 320
YSV D+WSLGL+L+E+A +P FG D M I
Sbjct: 413 PYSVTCDVWSLGLTLLEVAQAKFP------------FG---SDKMTATIAPIELLMLILT 457
Query: 321 LLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIA 380
+ +EP + ++S FK F++ CLKK+P ER + ++ H WI+ +KV++
Sbjct: 458 FSPQLKDEPELNI---VWSKSFKSFIEYCLKKDPSERPSPRQMIQHPWIQGQMKKKVNME 514
Query: 381 GWVCK 385
+V K
Sbjct: 515 KFVRK 519
>UniRef50_UPI0000D55779 Cluster: PREDICTED: similar to mitogen
activated protein kinase kinase 7; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to mitogen activated
protein kinase kinase 7 - Tribolium castaneum
Length = 645
Score = 206 bits (504), Expect = 6e-52
Identities = 127/339 (37%), Positives = 194/339 (57%), Gaps = 42/339 (12%)
Query: 60 EQIEMDDTQRRRIEVF--LCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMA 117
E +E D + +++ L K+ E D E+L ELG G G V+K+RHK +G I+A
Sbjct: 40 ENLETDRKLKEIMKISGNLTINNKLYETDIKDMERLEELGFGTCGHVIKMRHKLSGEIIA 99
Query: 118 RKLIHLEVKPAIKKQIIRELKVL---HECNFAHIVGFYGAFYSDGEISICMEYMDGGSLD 174
K + K+II +++V+ H+C + IV G F +D E+ ICME M D
Sbjct: 100 VKQMRRSGNNDENKRIIMDIEVVLKSHDCKY--IVQCLGCFITDSEVWICMELMTT-CFD 156
Query: 175 LILKKAGR-IPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGV 233
+LK+ G+ IPE ILG +T A ++ LSYL+DKH ++HRDVKPSNIL+++ G IK+CDFG+
Sbjct: 157 KLLKRLGKPIPEEILGKVTVATVEALSYLKDKHGVIHRDVKPSNILIDTKGHIKLCDFGI 216
Query: 234 SGQLIDSMANS-FVGTRSYMSPERLQ----GTHYSVQSDIWSLGLSLVEMAIGMYPIPPP 288
SG+L+DSMA + G +Y++PER++ Y +++D+WSLG++LVE+A G++ P P
Sbjct: 217 SGRLVDSMAKTRSAGCAAYLAPERIEPDPKNPDYDIRADVWSLGITLVELATGVF--PYP 274
Query: 289 DAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDR 348
+ T FE+L ++ + PP LP FS EF++FV
Sbjct: 275 NCTT-------------------------DFEVLTKVLGQDPPSLPE-TFSPEFREFVKF 308
Query: 349 CLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGWVCKTM 387
CL K+ +R L N +I+K E + V++ WV +
Sbjct: 309 CLIKDQKQRPKYAKLKNLSFIKKYEVKLVNVGEWVVNAL 347
>UniRef50_P46599 Cluster: Serine/threonine-protein kinase STE7
homolog; n=4; Saccharomycetales|Rep:
Serine/threonine-protein kinase STE7 homolog - Candida
albicans (Yeast)
Length = 589
Score = 205 bits (500), Expect = 2e-51
Identities = 127/310 (40%), Positives = 178/310 (57%), Gaps = 37/310 (11%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
+L++ D L +LG GN G V K+ H T MA+K+IH++ K I+ QIIREL++LHEC
Sbjct: 243 KLNNKDLLTLKQLGSGNSGSVSKILHIPTQKTMAKKIIHIDSKSVIQTQIIRELRILHEC 302
Query: 144 NFAHIVGFYGA-FYSDGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLS 200
+ +I+ FYGA ++ I ICMEY + GSLD IL + + P +L ++ A+L GL+
Sbjct: 303 HSPYIIEFYGACLNNNNTIVICMEYCNCGSLDKILPLCENKQFPTFVLKKLSFAILSGLT 362
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQ 258
YL H I+HRD+KP+N+L+ GE K+CDFGVS +L +S MA++FVGT YMSPER+Q
Sbjct: 363 YLYTTHKIIHRDIKPNNVLMTHKGEFKLCDFGVSRELTNSLAMADTFVGTSMYMSPERIQ 422
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAK-----------------TLAAIFGGQN 301
G Y V+SD+WS GL L+E+A G+ P+ D ++AA GQN
Sbjct: 423 GLDYGVKSDVWSTGLMLIELASGV-PVWSEDDNNNDDDEDDEDDAYVRQGSIAAERNGQN 481
Query: 302 ------EDHSPGQAPNSPR-PMAIFELLDYIVNEPPPKLPSGI-------FSDEFKDFVD 347
++ G NS P I +LL IVNE P L + I + F+D
Sbjct: 482 SPSRSRKNKQKGNGYNSYNGPEGILDLLQRIVNEDAPTLTNKINPVTKLPYDKYLCQFID 541
Query: 348 RCLKKNPDER 357
CL K+ R
Sbjct: 542 LCLIKDDSVR 551
>UniRef50_Q01AJ5 Cluster: MAPKK; n=2; Ostreococcus|Rep: MAPKK -
Ostreococcus tauri
Length = 310
Score = 203 bits (495), Expect = 7e-51
Identities = 119/306 (38%), Positives = 168/306 (54%), Gaps = 28/306 (9%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVK--PAIKKQIIRELKVLHECNFA 146
D E +G +G G+GGVV HK TG +A K I + + +K+I+ EL+ LH+
Sbjct: 16 DLELVGVIGTGSGGVVRLATHKRTGEALAVKTIAISLARDENERKRIVTELRTLHKSECD 75
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
+IV GA++ G +S+ MEYMDGG++ K G+ E L TS + GL YL K
Sbjct: 76 YIVRSSGAYFDRGSVSLVMEYMDGGTMSDATKYLGKWVEQDLAAATSMLADGLHYLHTKL 135
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLID-SMANSFVGTRSYMSPERLQGTHYSVQ 265
++HRD+KP N+L+N GE K+ DFGVSG L D S +S+VGT +YMSPER+QG Y
Sbjct: 136 NVVHRDIKPCNVLLNLRGEAKLSDFGVSGHLTDASKCHSWVGTVTYMSPERIQGESYEYT 195
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYI 325
+D+WS L++VE A+G +P PPD R + ++LLD +
Sbjct: 196 ADVWSFALTMVECALGRFPYNPPDVS----------------------RRLVFWDLLDIV 233
Query: 326 VNEPPPKL-PSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI--RKAEAEKVDIAGW 382
V +P P L P SDEF +FV L K+P R K ++ H WI R ++K IA
Sbjct: 234 VQDPVPNLRPELDVSDEFDNFVALGLNKDPTGRMLTKNMIAHPWIFGRDRASDKRRIAAL 293
Query: 383 VCKTMD 388
+ +D
Sbjct: 294 AARHLD 299
>UniRef50_Q17FJ2 Cluster: Dual specificity mitogen-activated protein
kinase kinase hemipterous MAPKK; n=2; Aedes aegypti|Rep:
Dual specificity mitogen-activated protein kinase kinase
hemipterous MAPKK - Aedes aegypti (Yellowfever mosquito)
Length = 977
Score = 202 bits (493), Expect = 1e-50
Identities = 116/300 (38%), Positives = 175/300 (58%), Gaps = 34/300 (11%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKV-LHECNFAH 147
+ + LGELG G G V+K+RH +G ++A K + K+II +L V L N +
Sbjct: 39 EMQDLGELGSGTSGHVVKMRHSPSGAVIAVKQMRRTGNDEENKRIIMDLDVVLKSENCRY 98
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKH 206
IV G F +D ++ ICME M D + KK+ + +PE ILG +T A + L+YL+D H
Sbjct: 99 IVKCLGCFITDADVWICMELMTT-CFDKLQKKSKKPVPERILGKVTVATVNALAYLKDNH 157
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYMSPERLQGTH--YS 263
++HRDVKPSNIL++ G IK+CDFG+SG+L+DS A + G +YM+PER+ + Y
Sbjct: 158 NVIHRDVKPSNILIDDRGNIKLCDFGISGRLVDSNARTRSAGCAAYMAPERIDPANQSYD 217
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLD 323
+++D+WSLG++LVE+A M+ P + KT FE+L
Sbjct: 218 IRADVWSLGITLVELATAMF--PYRNCKT-------------------------DFEVLT 250
Query: 324 YIVNEPPPKLPSGI-FSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGW 382
++ PP LP FS F+DFV CL+KN ++R L+ H ++++A+ E+VD+AGW
Sbjct: 251 KVLTSNPPSLPEDQDFSSHFRDFVKVCLRKNYEDRPKYPDLLKHPFLQRAKQEEVDVAGW 310
>UniRef50_A0CCZ2 Cluster: Chromosome undetermined scaffold_169,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_169,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 365
Score = 197 bits (481), Expect = 4e-49
Identities = 118/310 (38%), Positives = 170/310 (54%), Gaps = 23/310 (7%)
Query: 72 IEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKK 131
+++ + + +L +DFE + +LGQGN G V KV HK T A K IH +
Sbjct: 65 LDITYMESKHFKDLKLEDFEIVCKLGQGNYGSVEKVLHKPTHDYYALKKIHYVSNDVQES 124
Query: 132 QIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTI 191
+ +ELK L +CN ++V YGAFYS GEI I MEYMD GSL +IL+K +IPESI I
Sbjct: 125 LLKKELKALIDCNSQYVVQCYGAFYSKGEIYIVMEYMDMGSLSIILEKTKKIPESITMLI 184
Query: 192 TSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVS--GQLIDSMANSFVGTR 249
T VL+GL YL I+HRD+KP NIL+N GE+KI DFG+ + D ++F+GT
Sbjct: 185 TKEVLQGLDYLHTNKHIIHRDIKPHNILINKKGEVKIGDFGICSVSENSDQKFDTFIGTI 244
Query: 250 SYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQA 309
YMSPERL G Y DIWS+G+ ++ G+ P DAK ++ I Q +
Sbjct: 245 QYMSPERLNGEEYGYDCDIWSVGMMTMQCITGLLPF-EFDAKKMSMIEYIQMSKN----- 298
Query: 310 PNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
F++ DY + I+ F+ RCL++ P +R+ + L+ + I
Sbjct: 299 ---------FKIDDYFQQHKHAISENTIY------FISRCLQQEPKDRSKAQELLQTKAI 343
Query: 370 RKAEAEKVDI 379
+ ++ KVD+
Sbjct: 344 KYTQSLKVDV 353
>UniRef50_Q6FQU4 Cluster: Candida glabrata strain CBS138 chromosome
I complete sequence; n=1; Candida glabrata|Rep: Candida
glabrata strain CBS138 chromosome I complete sequence -
Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 451
Score = 197 bits (481), Expect = 4e-49
Identities = 126/312 (40%), Positives = 177/312 (56%), Gaps = 54/312 (17%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAI-KKQIIRELKVLHE-CNFA 146
D +LG+LG GN G VMKV H + ++A+K I +E AI K+QI REL ++
Sbjct: 103 DLVQLGKLGSGNSGTVMKVLHVPSSRVIAKKTIVIEQNNAIVKQQIYRELTIMRSVAEHR 162
Query: 147 HIVGFYGA--FYSDG-----EISICMEYMDGGSLDLI------LKKAGRIPES------- 186
+IV FYGA SD ++ I MEYM+ GSLD I L++ G + +
Sbjct: 163 NIVEFYGAHNLSSDSINGSNDVVILMEYMNCGSLDTITRTYKSLQRRGILAANRSYPVQE 222
Query: 187 ------ILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS 240
I+ I +VL GLSYL + + I+HRD+KPSN+L+NS G IK+CDFGVS +L +S
Sbjct: 223 WFSKPVIISRIAYSVLNGLSYLYENYKIIHRDIKPSNVLINSKGRIKLCDFGVSRKLNNS 282
Query: 241 MANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQ 300
+A++FVGT +YMSPER+QG Y+ + D+WSLGL L+E+ G +P+ GG
Sbjct: 283 IADTFVGTSTYMSPERIQGNKYTTKGDVWSLGLMLIELLTGEFPL------------GGH 330
Query: 301 NEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFS---DEFKDFVDRCLKKNPDER 357
N+ P I +LL IVNEP PKLPS + + +F+D C K +R
Sbjct: 331 ND-----------TPDGILDLLQRIVNEPAPKLPSSVIKVLPPDMVNFIDLCCVKVEKDR 379
Query: 358 ADLKTLMNHEWI 369
L+ L+ H +I
Sbjct: 380 GSLQELLKHPFI 391
>UniRef50_Q23977 Cluster: Dual specificity mitogen-activated protein
kinase kinase hemipterous; n=6; Eumetazoa|Rep: Dual
specificity mitogen-activated protein kinase kinase
hemipterous - Drosophila melanogaster (Fruit fly)
Length = 1178
Score = 196 bits (477), Expect = 1e-48
Identities = 118/305 (38%), Positives = 174/305 (57%), Gaps = 40/305 (13%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVL---HECN 144
+D + LG+LG G G V+K+ H S+ I+A K + K+I+ +L V+ H+C
Sbjct: 195 NDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCK 254
Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLR 203
+ IV G F D ++ ICME M D +LK + + +PE ILG +T A + LSYL+
Sbjct: 255 Y--IVKCLGCFVRDPDVWICMELMSM-CFDKLLKLSKKPVPEQILGKVTVATVNALSYLK 311
Query: 204 DKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYMSPERL--QGT 260
DKH ++HRDVKPSNIL++ G IK+CDFG+SG+L+DS AN+ G +YM+PER+ +
Sbjct: 312 DKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDPKKP 371
Query: 261 HYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFE 320
Y +++D+WSLG++LVE+A P + G N D FE
Sbjct: 372 KYDIRADVWSLGITLVELATARSP------------YEGCNTD---------------FE 404
Query: 321 LLDYIVNEPPPKLPSG---IFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKV 377
+L +++ PP LP G FS +F+DFV +CL KN +R L+ +IR E+ KV
Sbjct: 405 VLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKV 464
Query: 378 DIAGW 382
D+ W
Sbjct: 465 DVPNW 469
>UniRef50_Q59T28 Cluster: Likely protein kinase; n=3;
Saccharomycetales|Rep: Likely protein kinase - Candida
albicans (Yeast)
Length = 446
Score = 195 bits (475), Expect = 2e-48
Identities = 98/204 (48%), Positives = 139/204 (68%), Gaps = 11/204 (5%)
Query: 92 KLGELGQGNGGVVMK--VRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
++ LG+GNGG V K + I A KL+ + P ++KQI REL+V +C +IV
Sbjct: 160 EISSLGEGNGGAVTKCYIPQLPNKQIFALKLVMCDPNPDLQKQIFRELEVAKKCQHPNIV 219
Query: 150 GFYGAFYSDGE--ISICMEYMDGGSLDLILK------KAGRIPESILGTITSAVLKGLSY 201
+YG F + + I I ME+MDG SLD I K K RI E +LG I +++L GL Y
Sbjct: 220 KYYGTFLLEKQSMIGIAMEFMDGQSLDSIYKEVLKRDKTNRINEKVLGKIANSILSGLDY 279
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH 261
L K+ I+HRD+KPSNIL+++ G +K+CDFGVSG+ ++S A++FVGT+ YM+PER+ G +
Sbjct: 280 LHSKN-IIHRDIKPSNILLDTKGNVKLCDFGVSGEAVNSFASTFVGTQYYMAPERITGGN 338
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPI 285
YS+ SDIWSLG+SL+E+A G +PI
Sbjct: 339 YSITSDIWSLGMSLLEVANGCFPI 362
>UniRef50_P45985 Cluster: Dual specificity mitogen-activated protein
kinase kinase 4; n=44; Eumetazoa|Rep: Dual specificity
mitogen-activated protein kinase kinase 4 - Homo sapiens
(Human)
Length = 399
Score = 194 bits (472), Expect = 5e-48
Identities = 127/330 (38%), Positives = 185/330 (56%), Gaps = 40/330 (12%)
Query: 80 EKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKV 139
E+ + + +D + LGE+G+G G V K+ HK +G IMA K I V +KQ++ +L V
Sbjct: 92 EQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDV 151
Query: 140 -LHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-----IPESILGTITS 193
+ + +IV FYGA + +G+ ICME M S D K IPE ILG IT
Sbjct: 152 VMRSSDCPYIVQFYGALFREGDCWICMELMST-SFDKFYKYVYSVLDDVIPEEILGKITL 210
Query: 194 AVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYM 252
A +K L++L++ I+HRD+KPSNIL++ +G IK+CDFG+SGQL+DS+A + G R YM
Sbjct: 211 ATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYM 270
Query: 253 SPERLQGT----HYSVQSDIWSLGLSLVEMAIGMYPIPPPDA--KTLAAIFGGQNEDHSP 306
+PER+ + Y V+SD+WSLG++L E+A G +P P ++ L + G P
Sbjct: 271 APERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKG-----DP 325
Query: 307 GQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNH 366
Q NS E PS I +FV+ CL K+ +R K L+ H
Sbjct: 326 PQLSNS---------------EEREFSPSFI------NFVNLCLTKDESKRPKYKELLKH 364
Query: 367 EWIRKAEAEKVDIAGWVCKTMDLMPSTPNS 396
+I E V++A +VCK +D MP+TP+S
Sbjct: 365 PFILMYEERAVEVACYVCKILDQMPATPSS 394
>UniRef50_Q07192 Cluster: Dual specificity mitogen-activated protein
kinase kinase 2; n=10; Coelomata|Rep: Dual specificity
mitogen-activated protein kinase kinase 2 - Xenopus
laevis (African clawed frog)
Length = 446
Score = 192 bits (468), Expect = 1e-47
Identities = 125/330 (37%), Positives = 183/330 (55%), Gaps = 40/330 (12%)
Query: 80 EKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKV 139
E+ + + +D + LGE+G+G G V K+ H +G IMA K I V +KQ++ +L V
Sbjct: 139 EQHWDFTAEDLKDLGEIGRGAYGSVNKMSHTPSGQIMAVKRIRSTVDEKEQKQLLMDLDV 198
Query: 140 -LHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-----IPESILGTITS 193
+ + +IV FYGA + +G+ ICME M S D K IPE ILG IT
Sbjct: 199 VMRSSDCPYIVQFYGALFREGDCWICMELM-ATSFDKFYKYVYSFLDDVIPEEILGKITL 257
Query: 194 AVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYM 252
A +K L++L++ I+HRD+KPSNIL+++NG IK+CDFG+SGQL+DS+A + G R YM
Sbjct: 258 ATVKALNHLKENLKIIHRDIKPSNILLDTNGNIKLCDFGISGQLVDSIAKTRDAGCRPYM 317
Query: 253 SPERLQGT----HYSVQSDIWSLGLSLVEMAIGMYPIPPPDA--KTLAAIFGGQNEDHSP 306
+PER+ + Y V+SD+WSLG++L E+A G +P P ++ L + G P
Sbjct: 318 APERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKG-----DP 372
Query: 307 GQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNH 366
Q NS E P S FV++CL K+ +R K L+ H
Sbjct: 373 PQLSNSEE------------REFSPSFTS---------FVNQCLTKDESKRPKYKELLKH 411
Query: 367 EWIRKAEAEKVDIAGWVCKTMDLMPSTPNS 396
+I E VD+AG+V K ++ MP +P+S
Sbjct: 412 PFILMYEERTVDVAGYVGKILEQMPVSPSS 441
>UniRef50_UPI00015B4BE4 Cluster: PREDICTED: hypothetical protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
protein - Nasonia vitripennis
Length = 774
Score = 191 bits (465), Expect = 3e-47
Identities = 121/329 (36%), Positives = 182/329 (55%), Gaps = 47/329 (14%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVL---HECNF 145
D E LGELG G G V+K+RHK +G+++A K + K+II +L V+ H+C +
Sbjct: 116 DLEHLGELGNGTCGHVVKMRHKPSGVVIAVKQMRRSGNTDENKRIIMDLDVVLKSHDCPY 175
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRD 204
IV G F ++ ++ ICME M LD +LK++ + IPE LG +T A +K LSYL++
Sbjct: 176 --IVQCLGCFITESDVWICMELMVT-CLDKLLKRSRQAIPEDFLGKVTVATVKALSYLKE 232
Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYMSPERLQ----- 258
KH ++HRDVKPSNIL++ G +K+CDFG+SG+L+DS A + G +YM+PER+
Sbjct: 233 KHGVIHRDVKPSNILLDETGGVKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPT 292
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
Y +++D+WSLG++LVE+A G++P D KT + +D
Sbjct: 293 KPDYDIRADVWSLGITLVELATGVFPY--RDCKTDFEVLSRVVQD--------------- 335
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVD 378
+PP +FS EF++FV CL KN +R LM H +IRK E ++
Sbjct: 336 ---------DPPSLPSDALFSKEFQNFVSCCLTKNYKQRPKYNKLMEHPFIRKYELQQET 386
Query: 379 IAG-------WVCKTM-DLMPSTPNSNVS 399
+ W + M L P P S+++
Sbjct: 387 YSSTPSSGCQWFYRIMRQLEPRVPTSSIT 415
>UniRef50_O80396 Cluster: MAP kinase kinase 3; n=4; core
eudicotyledons|Rep: MAP kinase kinase 3 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 520
Score = 190 bits (463), Expect = 6e-47
Identities = 117/310 (37%), Positives = 174/310 (56%), Gaps = 33/310 (10%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
+ + + G +G G VV + H I+A K I++ + ++Q++ E++ L E
Sbjct: 77 QCASHEMRVFGAIGSGASSVVQRAIHIPNHRILALKKINIFEREK-RQQLLTEIRTLCEA 135
Query: 144 NFAH-IVGFYGAFYS--DGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLS 200
+V F+GAFYS G+ISI +EYM+GGSL ILK +IPE +L ++ +L+GLS
Sbjct: 136 PCHEGLVDFHGAFYSPDSGQISIALEYMNGGSLADILKVTKKIPEPVLSSLFHKLLQGLS 195
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQ 258
YL ++HRD+KP+N+L+N GE KI DFG+S L +SMA +FVGT +YMSPER++
Sbjct: 196 YLHGVRHLVHRDIKPANLLINLKGEPKITDFGISAGLENSMAMCATFVGTVTYMSPERIR 255
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
YS +DIWSLGL+L E G +P + + P + +
Sbjct: 256 NDSYSYPADIWSLGLALFECGTGEFP-------------------YIANEGPVN----LM 292
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVD 378
++LD +P P P FS EF F+D CL+K+PD R L++H +I K E E+VD
Sbjct: 293 LQILD----DPSPTPPKQEFSPEFCSFIDACLQKDPDARPTADQLLSHPFITKHEKERVD 348
Query: 379 IAGWVCKTMD 388
+A +V D
Sbjct: 349 LATFVQSIFD 358
>UniRef50_UPI00003C01CC Cluster: PREDICTED: similar to
mitogen-activated protein kinase kinase 7; n=3;
Coelomata|Rep: PREDICTED: similar to mitogen-activated
protein kinase kinase 7 - Apis mellifera
Length = 762
Score = 188 bits (458), Expect = 2e-46
Identities = 114/293 (38%), Positives = 166/293 (56%), Gaps = 39/293 (13%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVL---HECNF 145
D E LGELG G G V+K+RHK +G+++A K + K+II +L V+ H+C +
Sbjct: 99 DLEHLGELGNGTCGHVVKMRHKPSGVLIAVKQMRRSGNAEENKRIIMDLDVVLKSHDCPY 158
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRD 204
IV G F ++ ++ ICME M LD +LKK + +PE LG +T A +K LSYL++
Sbjct: 159 --IVQCLGCFITESDVWICMELM-ATCLDKLLKKTRQAMPEEFLGKVTVATVKALSYLKE 215
Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYMSPERLQ----- 258
KH ++HRDVKPSNIL++ G +K+CDFG+SG+L+DS A + G +YM+PER+
Sbjct: 216 KHGVIHRDVKPSNILLDERGGVKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPT 275
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
Y +++D+WSLG++LVE+A G++P D KT + +D P P++
Sbjct: 276 KPDYDIRADVWSLGITLVELATGVFPY--RDCKTDFEVLSRVVQDDPPSLPPDAS----- 328
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
FS EF++FV CL KN R LM H +IRK
Sbjct: 329 -------------------FSKEFRNFVSCCLTKNYKHRPKYHKLMEHPFIRK 362
>UniRef50_A3FK65 Cluster: Mitogen-activated protein kinase kinase 3;
n=9; Oryza sativa|Rep: Mitogen-activated protein kinase
kinase 3 - Oryza sativa subsp. indica (Rice)
Length = 523
Score = 188 bits (458), Expect = 2e-46
Identities = 116/314 (36%), Positives = 172/314 (54%), Gaps = 33/314 (10%)
Query: 80 EKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKV 139
EK + D G +G G VV + I+A K I++ K ++QI+ E++
Sbjct: 77 EKAYRCASHDMHIFGPIGNGASSVVQRAVFIPVHRILALKKINIFEKEK-RQQILNEMRT 135
Query: 140 LHE-CNFAHIVGFYGAFY--SDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVL 196
L E C + +V F GAFY G+ISI +EYMDGGSL ++K IPE +L + VL
Sbjct: 136 LCEACCYIGLVEFQGAFYMPDSGQISIALEYMDGGSLADVIKIKKSIPEPVLAHMLQKVL 195
Query: 197 KGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSP 254
GL YL + ++HRD+KP+N+LVN GE KI DFGVS L ++MA +FVGT +YMSP
Sbjct: 196 LGLRYLHEVRHLVHRDIKPANLLVNLKGEAKITDFGVSAGLDNTMAMCATFVGTVTYMSP 255
Query: 255 ERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPR 314
ER++ +YS +DIWSLGL+++E A G +P N + P
Sbjct: 256 ERIRNENYSYAADIWSLGLAILECATGKFP---------------YNVNEGPA------- 293
Query: 315 PMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEA 374
L+ I+++P P P +S EF F++ CL+K+ D R + L++H +I++ E
Sbjct: 294 -----NLMLQILDDPSPTPPKDSYSSEFCSFINDCLQKDADARPSCEQLLSHPFIKRYEN 348
Query: 375 EKVDIAGWVCKTMD 388
VD+ +V +D
Sbjct: 349 TTVDLVAYVKSIVD 362
>UniRef50_Q4H379 Cluster: Mitogen-activated protein kinase kinase;
n=1; Ciona intestinalis|Rep: Mitogen-activated protein
kinase kinase - Ciona intestinalis (Transparent sea
squirt)
Length = 478
Score = 188 bits (457), Expect = 3e-46
Identities = 118/317 (37%), Positives = 177/317 (55%), Gaps = 43/317 (13%)
Query: 82 IGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVL- 140
I E + FE LG++G G G V K+R+ TG +MA K +H K+I+ +L ++
Sbjct: 122 IYEAKVEQFENLGQIGSGTCGQVYKMRY-ITGHVMAVKQMHRSGNREENKRILMDLDIVQ 180
Query: 141 --HECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKA-GRIPESILGTITSAVLK 197
H+C +IV YG F ++ + ICME M+ D + KK G +PE+ILG +T +V+K
Sbjct: 181 KSHDC--PNIVKCYGTFVTEVNVWICMELMET-CFDKLKKKINGPMPENILGKLTVSVVK 237
Query: 198 GLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYMSPER 256
L YL++KH ++HRDVKPSNILVN G++K+CDFG+SG+L+DS A + G +YM+PER
Sbjct: 238 ALHYLKEKHGVIHRDVKPSNILVNKLGDVKLCDFGISGRLVDSQAKTRAAGCTAYMAPER 297
Query: 257 L----QGTHYSVQSDIWSLGLSLVEMAIGMYPIP--PPDAKTLAAIFGGQNEDHSPGQAP 310
+ +Y +++D+WSLG+SLVE+A G++P D + L I + +P + P
Sbjct: 298 ISPDPSHPNYDIRADVWSLGISLVELATGVFPYHNCKTDFEMLTKIL-----EEAPPELP 352
Query: 311 NSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370
N FS FK FV C K+ R + L+ HE++R
Sbjct: 353 NDQN-----------------------FSIGFKRFVSFCCTKDYRYRPKYRDLLEHEFVR 389
Query: 371 KAEAEKVDIAGWVCKTM 387
+ E VDI W+ K +
Sbjct: 390 RHEHSMVDIPAWLRKVL 406
>UniRef50_Q9FX43 Cluster: MAP kinase, putative; n=11; core
eudicotyledons|Rep: MAP kinase, putative - Arabidopsis
thaliana (Mouse-ear cress)
Length = 310
Score = 186 bits (452), Expect = 1e-45
Identities = 114/296 (38%), Positives = 168/296 (56%), Gaps = 38/296 (12%)
Query: 85 LSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN 144
+S D EKL LG GNGG+V KVRHK+T I A K ++ ++ P +Q++RE+++L +
Sbjct: 42 ISACDLEKLNVLGCGNGGIVYKVRHKTTSEIYALKTVNGDMDPIFTRQLMREMEILRRTD 101
Query: 145 FAHIVGFYGAFYSD--GEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202
++V +G F GE+SI MEYMDGG+L+ + G + E L +LKGLSYL
Sbjct: 102 SPYVVKCHGIFEKPVVGEVSILMEYMDGGTLESL---RGGVTEQKLAGFAKQILKGLSYL 158
Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-- 258
I+HRD+KP+N+L+NS E+KI DFGVS L+ S+ NS+VGT +YMSPER
Sbjct: 159 H-ALKIVHRDIKPANLLLNSKNEVKIADFGVSKILVRSLDSCNSYVGTCAYMSPERFDSE 217
Query: 259 ---GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRP 315
G+ DIWS GL ++E+ +G +P+ PP GQ D +
Sbjct: 218 SSGGSSDIYAGDIWSFGLMMLELLVGHFPLLPP----------GQRPDWA---------- 257
Query: 316 MAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
L+ + PP+ P G S+EF+ FV+ CL+K+ +R L+ H ++R+
Sbjct: 258 ----TLMCAVCFGEPPRAPEGC-SEEFRSFVECCLRKDSSKRWTAPQLLAHPFLRE 308
>UniRef50_A0DZW8 Cluster: Chromosome undetermined scaffold_70, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_70,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 352
Score = 182 bits (443), Expect = 1e-44
Identities = 93/208 (44%), Positives = 127/208 (61%), Gaps = 3/208 (1%)
Query: 80 EKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKV 139
E LS ++ +G LGQG G V KV+ + TG A K I + P KQ+ ELK+
Sbjct: 62 ESTHNLSLENLVTVGHLGQGASGQVEKVQDQVTGQYFAMKKIPVASDPQYLKQLSDELKL 121
Query: 140 LHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGL 199
EC+ ++V YGAFY G + I +EYMD GS+D ++KK + E ++ + +L G+
Sbjct: 122 ALECSSPYVVKCYGAFYKSGTLHIILEYMDVGSIDSLIKKVKNLNEPVMALLLYQILLGI 181
Query: 200 SYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPERL 257
YL +K I+HRD+KP NILVN GEIKI DFG+SG I++M ++VGT YMSPERL
Sbjct: 182 DYLHNKKKIIHRDIKPQNILVNKKGEIKITDFGISG-TIETMQQRKTYVGTAVYMSPERL 240
Query: 258 QGTHYSVQSDIWSLGLSLVEMAIGMYPI 285
G Y SDIWS+G+ E +G +PI
Sbjct: 241 NGEMYGKDSDIWSIGILTAECLMGKHPI 268
>UniRef50_A0BSN2 Cluster: Chromosome undetermined scaffold_125,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_125,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 331
Score = 182 bits (443), Expect = 1e-44
Identities = 97/215 (45%), Positives = 131/215 (60%), Gaps = 2/215 (0%)
Query: 77 CQKE-KIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR 135
C+K+ K ++ +DF+ + +LGQG G V KV+ K T + A K I +K + R
Sbjct: 41 CKKDQKQQNITLNDFQLVTKLGQGGFGSVEKVQLKGTQEMYALKKIKFLSDTNQEKLLTR 100
Query: 136 ELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAV 195
EL L C IV YGAFYS G I I +EYMD GSLD +L+K G I E ++ IT +
Sbjct: 101 ELDALISCESDFIVQCYGAFYSQGYICIWLEYMDLGSLDRLLQKDGLIKEPMMMMITYKI 160
Query: 196 LKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL-IDSMANSFVGTRSYMSP 254
L+GL YL KH I+HRD+KP NIL+NS G +KI DFG+ + N+++GT YMSP
Sbjct: 161 LQGLDYLHYKHKIIHRDIKPHNILINSEGNVKIADFGICQTVSTGQYLNTYIGTAIYMSP 220
Query: 255 ERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPD 289
ERLQ +Y + +DIWSLG+ L+E G +P D
Sbjct: 221 ERLQSMNYGMDADIWSLGIMLIECLSGQHPFKKKD 255
>UniRef50_Q86IX1 Cluster: Similar to Oryza sativa (Rice). 36I5.3;
n=2; Dictyostelium discoideum|Rep: Similar to Oryza
sativa (Rice). 36I5.3 - Dictyostelium discoideum (Slime
mold)
Length = 737
Score = 182 bits (442), Expect = 2e-44
Identities = 104/277 (37%), Positives = 161/277 (58%), Gaps = 31/277 (11%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
LG+G+ G V K H + G ++A K+I L+ + AIK + +E+ +L ECN+ +IV ++G++
Sbjct: 35 LGKGSFGQVFKAVHFANGKVVAIKIISLDDQEAIK-DVRKEISILAECNYPNIVQYFGSY 93
Query: 156 YSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKP 215
+ D ++ I MEY GGS+ +L+ I E + I LKGL+YL + I HRD+K
Sbjct: 94 FKDHQLWIVMEYCGGGSVSDLLQVIDTISEDEIALICREALKGLNYLHEFKKI-HRDIKG 152
Query: 216 SNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGL 273
NIL+N GE+K+ DFGVS QL + S N+FVGT +M+PE +Q Y ++D+WSLG+
Sbjct: 153 GNILLNDRGEVKLADFGVSAQLFNTFSKRNTFVGTPYWMAPEVIQENKYDGKADVWSLGI 212
Query: 274 SLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKL 333
+ +EMA G+ PP++ PM + ++ E P
Sbjct: 213 TAIEMAEGL----PPNSNV---------------------HPMRVIFMIPR--EESPALT 245
Query: 334 PSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370
I+SD+F+DF+ +CL K+P ER K L+NHE+I+
Sbjct: 246 DKSIWSDKFQDFISKCLTKDPAERPTAKELLNHEFIQ 282
>UniRef50_Q2WBY4 Cluster: MAP kinase kinase; n=1; Platynereis
dumerilii|Rep: MAP kinase kinase - Platynereis dumerilii
(Dumeril's clam worm)
Length = 401
Score = 176 bits (429), Expect = 7e-43
Identities = 96/213 (45%), Positives = 136/213 (63%), Gaps = 9/213 (4%)
Query: 80 EKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKV 139
E+ ++ DDF+ + LG+G GVV K++H TG I+A K + ++ A K ++ +L V
Sbjct: 110 EQTYDVGTDDFQFVDTLGRGAYGVVDKMKHPPTGTIVAVKRLAYSLESADYKSLLMDLNV 169
Query: 140 -LHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR----IPESILGTITSA 194
L + +IV FYGA + G++ I ME MD SLD KK + I E L IT
Sbjct: 170 SLRTGHCPNIVHFYGALFGRGDVWIFMEVMDT-SLDKFYKKVYQHKMTIKEPALAKITLG 228
Query: 195 VLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSP 254
V+ GLSYL++K +++HRDVKPSNIL N G IK+CDF VSG LIDS++ + +G R YM+P
Sbjct: 229 VMMGLSYLKEKLSVIHRDVKPSNILANRQGNIKLCDFSVSGNLIDSLSKTKIGARPYMAP 288
Query: 255 ERLQ---GTHYSVQSDIWSLGLSLVEMAIGMYP 284
E++ H+ V+SDIWSLG SL+E+A G +P
Sbjct: 289 EKVNPDGEQHFDVRSDIWSLGXSLIELATGKFP 321
Score = 49.6 bits (113), Expect = 1e-04
Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVD 378
FE + +V P P LP+ FS + +DFV++CL K+ R L+ H ++ +EA + D
Sbjct: 329 FEQIKQVVQGPSPTLPNEGFSPQIQDFVNKCLLKDYHLRPKYPELLKHPFV--SEAHETD 386
Query: 379 IAGWVCKTMDL 389
IA ++ +DL
Sbjct: 387 IADFISLILDL 397
>UniRef50_P46734 Cluster: Dual specificity mitogen-activated protein
kinase kinase 3; n=80; Eumetazoa|Rep: Dual specificity
mitogen-activated protein kinase kinase 3 - Homo sapiens
(Human)
Length = 347
Score = 176 bits (429), Expect = 7e-43
Identities = 92/211 (43%), Positives = 136/211 (64%), Gaps = 11/211 (5%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKV-LHE 142
E+ DD + ELG+G GVV KVRH +G IMA K I V +K+++ +L + +
Sbjct: 58 EVEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRT 117
Query: 143 CNFAHIVGFYGAFYSDGEISICMEYMDGGSLDL----ILKKAGRIPESILGTITSAVLKG 198
+ + V FYGA + +G++ ICME MD SLD +L K IPE ILG I ++++
Sbjct: 118 VDCFYTVTFYGALFREGDVWICMELMDT-SLDKFYRKVLDKNMTIPEDILGEIAVSIVRA 176
Query: 199 LSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSF-VGTRSYMSPER- 256
L +L K +++HRDVKPSN+L+N G +K+CDFG+SG L+DS+A + G + YM+PER
Sbjct: 177 LEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERI 236
Query: 257 ---LQGTHYSVQSDIWSLGLSLVEMAIGMYP 284
L Y+V+SD+WSLG++++EMAI +P
Sbjct: 237 NPELNQKGYNVKSDVWSLGITMIEMAILRFP 267
Score = 62.5 bits (145), Expect = 2e-08
Identities = 29/65 (44%), Positives = 39/65 (60%)
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVD 378
F+ L +V EP P+LP+ FS EF DF +CL+KNP ER LM H + + +K D
Sbjct: 275 FQQLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTD 334
Query: 379 IAGWV 383
IA +V
Sbjct: 335 IAAFV 339
>UniRef50_Q23CK7 Cluster: Protein kinase domain containing protein;
n=2; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 249
Score = 176 bits (428), Expect = 1e-42
Identities = 102/237 (43%), Positives = 144/237 (60%), Gaps = 30/237 (12%)
Query: 130 KKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILG 189
+KQ+I E+K L CN HIV +Y AFY++ + + +EYMD G+LD ILKK ++ E IL
Sbjct: 3 QKQLIWEIKTLFSCNSPHIVQYYCAFYTECMLHLILEYMDMGTLDTILKKTKQVSEPILI 62
Query: 190 TITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVG 247
T ++KG+ YL I+HRD+KP NILVNS GEIKI D G+ G++ +M N+FVG
Sbjct: 63 YTTYQIIKGIHYLHKDLKIIHRDLKPGNILVNSEGEIKISDLGICGKVNGTMDQKNTFVG 122
Query: 248 TRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPG 307
T YMSPERL G Y++++DIWS+GL L+E + G +PI
Sbjct: 123 TTIYMSPERLNGDSYTMKTDIWSVGLLLIEFSEGKHPI---------------------- 160
Query: 308 QAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLM 364
QA N+ FE+L+ I++ P L I S EF +F++ CLK + +ERAD+ L+
Sbjct: 161 QASNN-----FFEVLNNIIDFKIPPL-KNINSPEFTNFIEICLKSDQNERADITQLL 211
>UniRef50_Q95YI9 Cluster: MAP kinase kinase SEK-1; n=2;
Caenorhabditis|Rep: MAP kinase kinase SEK-1 -
Caenorhabditis elegans
Length = 336
Score = 175 bits (426), Expect = 2e-42
Identities = 89/216 (41%), Positives = 145/216 (67%), Gaps = 11/216 (5%)
Query: 78 QKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIREL 137
+ E+I E++ D L ELG+G G+V K++H+ +G+IMA K I + +KQ++ EL
Sbjct: 39 ESEEI-EIAATDLVVLEELGKGGYGIVEKMQHRQSGIIMAVKRIKSSINDQSQKQMLNEL 97
Query: 138 KVLHECNFA-HIVGFYGAFYSDGEISICMEYMDGGSLDLILK---KAGR-IPESILGTIT 192
+ +V FYGA + +G++ ICME MD SLD + K G+ IPE +G +
Sbjct: 98 DACRRSDCCPQMVRFYGAMFREGDVWICMEVMDT-SLDKFYRHAYKIGKHIPEPFIGKMA 156
Query: 193 SAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSF-VGTRSY 251
+V++GL++++++ ++HRDVKPSNIL+N +G++KICDFG+SG L +SMA + G + Y
Sbjct: 157 LSVIEGLNFMKEQLNLIHRDVKPSNILLNRHGQVKICDFGISGHLTNSMAKTVQAGCKPY 216
Query: 252 MSPERLQG---THYSVQSDIWSLGLSLVEMAIGMYP 284
M PER+ G + Y V++D+WSLG++++E+A+G +P
Sbjct: 217 MPPERIDGETKSAYDVRADVWSLGITIIEIAVGTHP 252
>UniRef50_O14733 Cluster: Dual specificity mitogen-activated protein
kinase kinase 7; n=32; Deuterostomia|Rep: Dual
specificity mitogen-activated protein kinase kinase 7 -
Homo sapiens (Human)
Length = 419
Score = 175 bits (426), Expect = 2e-42
Identities = 113/320 (35%), Positives = 171/320 (53%), Gaps = 37/320 (11%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVL---HECN 144
+D E LGE+G G G V K+R + TG ++A K + K+I+ +L V+ H+C
Sbjct: 118 NDLENLGEMGSGTCGQVWKMRFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKSHDCP 177
Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRD 204
+ IV +G F ++ ++ I ME M + L + G IPE ILG +T A++K L YL++
Sbjct: 178 Y--IVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKE 235
Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYMSPERLQ----- 258
KH ++HRDVKPSNIL++ G+IK+CDFG+SG+L+DS A + G +YM+PER+
Sbjct: 236 KHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPT 295
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
Y +++D+WSLG+SLVE+A G +P + KT + ++ + P P M
Sbjct: 296 KPDYDIRADVWSLGISLVELATGQFPY--KNCKTDFEVLTKVLQE----EPPLLPGHMGF 349
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVD 378
SG F KD CL K+ +R L+ H +I++ E +VD
Sbjct: 350 ----------------SGDFQSFVKD----CLTKDHRKRPKYNKLLEHSFIKRYETLEVD 389
Query: 379 IAGWVCKTMDLMPSTPNSNV 398
+A W M S S V
Sbjct: 390 VASWFKDVMAKTESPRTSGV 409
>UniRef50_Q2H575 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 605
Score = 175 bits (425), Expect = 2e-42
Identities = 81/155 (52%), Positives = 115/155 (74%), Gaps = 2/155 (1%)
Query: 111 STGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDG 170
++G++MA K I LE+ A I++EL +LHEC +I+ FYGAFY +G + +C+EYMDG
Sbjct: 335 TSGVVMAMKEIRLELDQAKFTTILKELVILHECVSPYIIDFYGAFYQEGAVYMCIEYMDG 394
Query: 171 GSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICD 230
GS+D + AG IPE++L IT A + GL L+D H I+HRDVKP+NILVNSNG++KICD
Sbjct: 395 GSIDKLY--AGGIPENVLRKITFATIVGLKTLKDDHNIIHRDVKPTNILVNSNGQVKICD 452
Query: 231 FGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQ 265
FGVSG L+ S+A + +G +SYM+PER++ S++
Sbjct: 453 FGVSGNLVASIAKTNIGCQSYMAPERIKRRRLSLR 487
>UniRef50_Q13188 Cluster: Serine/threonine-protein kinase 3; n=84;
Metazoa|Rep: Serine/threonine-protein kinase 3 - Homo
sapiens (Human)
Length = 491
Score = 173 bits (421), Expect = 7e-42
Identities = 103/298 (34%), Positives = 170/298 (57%), Gaps = 34/298 (11%)
Query: 79 KEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELK 138
++ + + ++ F+ L +LG+G+ G V K HK +G ++A K + +E + ++II+E+
Sbjct: 16 EDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVE---SDLQEIIKEIS 72
Query: 139 VLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLK 197
++ +C+ ++V +YG+++ + ++ I MEY GS+ D+I + + E + TI + LK
Sbjct: 73 IMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLK 132
Query: 198 GLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPE 255
GL YL I HRD+K NIL+N+ G K+ DFGV+GQL D+MA N+ +GT +M+PE
Sbjct: 133 GLEYLHFMRKI-HRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPE 191
Query: 256 RLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRP 315
+Q Y+ +DIWSLG++ +EMA G P D + AIF P +P
Sbjct: 192 VIQEIGYNCVADIWSLGITSIEMAEGKPPY--ADIHPMRAIF----------MIPTNP-- 237
Query: 316 MAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
PP ++SD+F DFV +CL KNP++RA L+ H +I+ A+
Sbjct: 238 -------------PPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAK 282
>UniRef50_Q22553 Cluster: Germinal center kinase family protein 1,
isoform a; n=5; Caenorhabditis|Rep: Germinal center
kinase family protein 1, isoform a - Caenorhabditis
elegans
Length = 653
Score = 172 bits (418), Expect = 2e-41
Identities = 101/290 (34%), Positives = 165/290 (56%), Gaps = 32/290 (11%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F K +G+G+ G V K TG ++A K+I LE + I +E++VL +C+ ++
Sbjct: 34 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVT 93
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
++G+F ++ I MEY+ GGS L L K+G++ ES + I +LKGL YL + I
Sbjct: 94 KYFGSFLKGSKLWIIMEYLGGGSA-LDLTKSGKLDESHIAVILREILKGLEYLHSERKI- 151
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTHYSVQSD 267
HRD+K +N+LV+ +G++K+ DFGV+GQL +++ +FVG+ +M+PE ++ + Y ++D
Sbjct: 152 HRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRITFVGSPFWMAPELIKQSSYDYKAD 211
Query: 268 IWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVN 327
IWSLG++ +E+A G PP HS PM + L I
Sbjct: 212 IWSLGITAIELANG----EPP---------------HS------DLHPMRVLFL---IPK 243
Query: 328 EPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKV 377
PPP L +S FK+FV+ CL K+P+ R TL+ H++I++A+ +
Sbjct: 244 NPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIKRAKKNSI 293
>UniRef50_Q6C8H9 Cluster: Similar to tr|Q871H9 Neurospora crassa
B16M17.090 Related to Ste20- like kinase Don3; n=1;
Yarrowia lipolytica|Rep: Similar to tr|Q871H9 Neurospora
crassa B16M17.090 Related to Ste20- like kinase Don3 -
Yarrowia lipolytica (Candida lipolytica)
Length = 547
Score = 172 bits (418), Expect = 2e-41
Identities = 114/290 (39%), Positives = 161/290 (55%), Gaps = 33/290 (11%)
Query: 86 SDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNF 145
S D FE L ELG G+ GVV K K +G I+A K I LE ++I +E+ +L C
Sbjct: 54 SADQFELLEELGSGSFGVVYKAIDKVSGQIVAVKKIDLESSEDDIEEIQKEIAILSGCQD 113
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGS-LDLILKKAGRIPESILGTITSAVLKGLSYLRD 204
HI +YG F ++ I MEY+ GGS LDL+ K G E + + +L+GL YL D
Sbjct: 114 EHITTYYGCFVRGYKLWIIMEYLAGGSGLDLL--KPGIFHEPEIAVMCRELLEGLIYLHD 171
Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHY 262
I HRDVK +N+LV+S G +K+ DFGV+ QL ++M+ N+FVGT +M+PE ++ Y
Sbjct: 172 NGKI-HRDVKAANVLVSSEGSVKLADFGVATQLSNNMSRRNTFVGTPFWMAPEVIRQEDY 230
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322
++DIWSLG++ +E A G P+ +E H PM + L+
Sbjct: 231 DTKADIWSLGITAIEFAKGEPPL---------------SEYH----------PMKVLFLI 265
Query: 323 DYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
EPP G +S +F+DFV CL+KNP ER + L+ H +IRKA
Sbjct: 266 PKA--EPPTVPAGGNWSADFRDFVACCLRKNPAERPSGRQLLKHRFIRKA 313
>UniRef50_Q4Q1Z0 Cluster: Protein kinase, putative; n=5;
Trypanosomatidae|Rep: Protein kinase, putative -
Leishmania major
Length = 514
Score = 171 bits (417), Expect = 2e-41
Identities = 115/283 (40%), Positives = 163/283 (57%), Gaps = 35/283 (12%)
Query: 94 GELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA--HIVGF 151
G LG+G+ G V + H+ + ++A K I + + I +I REL+ LH +FA ++V F
Sbjct: 63 GFLGKGSSGSVRRAVHRGSKKMVAVKEIKVTGQTHIN-EIRRELETLHAGDFATPYLVSF 121
Query: 152 YGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHR 211
YGAF +G + I ME MDG SL + K +P +L +IT +LKGL+YL ++HR
Sbjct: 122 YGAFAHEGSVFIAMEAMDG-SLHELYKP---VPPPVLASITRLMLKGLTYLHRTRHLIHR 177
Query: 212 DVKPSNILVNSN-GEIKICDFGVSGQL--IDSMANSFVGTRSYMSPERLQGTHYSVQSDI 268
D+KPSN+L NS G+IKI DFGVS L + A+SFVGT +YMSPERL+G HYS +DI
Sbjct: 178 DLKPSNVLYNSRTGDIKISDFGVSSNLECTKADAHSFVGTVTYMSPERLRGEHYSYGADI 237
Query: 269 WSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL--DYIV 326
WSLGL + E+A+G+ P A + GG +E R A+ + L D
Sbjct: 238 WSLGLVVAELAVGVCP--------YAGLRGGSSE----------ARFWALLQHLNGDGAA 279
Query: 327 NEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
E PP++ S + DF+ C+ K+PD R L+ H +I
Sbjct: 280 LELPPEMDS-----DLADFISACVVKSPDRRPTCTELLRHPFI 317
>UniRef50_A2EML4 Cluster: STE family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: STE family protein kinase
- Trichomonas vaginalis G3
Length = 332
Score = 170 bits (414), Expect = 5e-41
Identities = 103/299 (34%), Positives = 163/299 (54%), Gaps = 30/299 (10%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148
D L +G+G V +V+ TG I A K I K I+ E+ ++ ++
Sbjct: 38 DLTFLDFVGKGAFSTVYRVKMNDTGEIYALKKIKYAETQEQLKVIVNEIDCMNTLRHPNV 97
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+ Y FY G I I M Y++G +L LK PE+ LG I+ ++GL YLR K+A
Sbjct: 98 LRLYNVFYQSGAIHIIMPYINGLTLAEALKIMPIPPEAQLGRISYLAVQGLHYLR-KNAY 156
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYSVQS 266
+HRD+KPSNIL++ G++ I DFG++ QL S A S+VGT SYM+PER++G Y +S
Sbjct: 157 IHRDLKPSNILLSLEGQVLIADFGLARQLTASSEQACSYVGTISYMAPERIKGKEYQFKS 216
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
D+WSLG+ + +MA+G +P+P P + +++LD++
Sbjct: 217 DVWSLGIIIYQMALGHFPLP------------------------KDPAQVTYWDILDFVD 252
Query: 327 NEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK--AEAEKVDIAGWV 383
E +LP ++ +FK F+ +CL NP++R+D+ L+N WI+K + A D+ W+
Sbjct: 253 KEVRIELPDP-YAPDFKAFLMKCLYPNPEQRSDVNELVNDPWIQKFSSPAYDADLKKWI 310
>UniRef50_Q8T0S6 Cluster: Serine/threonine-protein kinase hippo;
n=5; Eumetazoa|Rep: Serine/threonine-protein kinase
hippo - Drosophila melanogaster (Fruit fly)
Length = 669
Score = 167 bits (407), Expect = 3e-40
Identities = 109/293 (37%), Positives = 168/293 (57%), Gaps = 38/293 (12%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F+ + +LG+G+ G V K HK + I+A KL+ +E + +II+E+ ++ +C+ ++V
Sbjct: 42 FDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVE---SDLHEIIKEISIMQQCDSPYVV 98
Query: 150 GFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+YG+++ ++ ICMEY GS+ D++ + + E + TI S L+GL YL + I
Sbjct: 99 RYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKI 158
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQS 266
HRD+K +NIL+N+ G K+ DFGV+GQL D+MA N+ +GT +M+PE ++ Y +
Sbjct: 159 -HRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDCVA 217
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPM-AIFELLDYI 325
DIWSLG++ +EMA G PP +G E H PM AIF I
Sbjct: 218 DIWSLGITALEMAEGK---PP---------YG---EIH----------PMRAIF----MI 248
Query: 326 VNEPPPKL-PSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKV 377
+PPP +S EF DFV +CL K PD+RA L+ HE+IR A+ +
Sbjct: 249 PQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFIRNAKHRSI 301
>UniRef50_Q175W2 Cluster: Serine/threonine protein kinase; n=2;
Culicidae|Rep: Serine/threonine protein kinase - Aedes
aegypti (Yellowfever mosquito)
Length = 596
Score = 165 bits (402), Expect = 1e-39
Identities = 103/298 (34%), Positives = 163/298 (54%), Gaps = 34/298 (11%)
Query: 79 KEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELK 138
+E + ++ F+ + +LG+G+ G V K HK + ++A K + ++ ++II+E+
Sbjct: 12 EESLTRQPEEVFDIICKLGEGSYGSVYKALHKESEQVLAIKQVPVDTD---LQEIIKEIS 68
Query: 139 VLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLK 197
++ +C+ ++V +YG+++ + ++ I MEY GS+ D++ + + E + TI LK
Sbjct: 69 IMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRKKTLSEDEIATILIDTLK 128
Query: 198 GLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPE 255
GL YL + I HRD+K NIL+NS G K+ DFGV+GQL D+MA N+ +GT +M+PE
Sbjct: 129 GLEYLHLRRKI-HRDIKAGNILLNSEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPE 187
Query: 256 RLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRP 315
++ Y +DIWSLG++ +EMA G P D + AIF P P
Sbjct: 188 VIEEIGYDCVADIWSLGITALEMAEGKPPY--GDIHPMRAIF----------MIPTKP-- 233
Query: 316 MAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
PP I+S EF DFV CL KNP+ERA L+ HE+I A+
Sbjct: 234 -------------PPSFRDPDIWSPEFIDFVSLCLVKNPEERATATDLLTHEFIGNAK 278
>UniRef50_A0EIS6 Cluster: Chromosome undetermined scaffold_99, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_99,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 366
Score = 165 bits (402), Expect = 1e-39
Identities = 109/310 (35%), Positives = 165/310 (53%), Gaps = 43/310 (13%)
Query: 92 KLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELK-VLHECNFAHIV 149
K+G+ +GQG V + + +A K+I++ K + Q++ +L +L+ C ++
Sbjct: 69 KVGDVIGQGVSSYVCRGLYLPYNCQVALKIINVFDKDK-RHQMLNDLSTLLNGCECEQLI 127
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGR------IPESILGTITSAVLKGLSYLR 203
FYGA+Y +G I + +EYMD GSL I+++ + I E I+ TIT +L GL YL
Sbjct: 128 KFYGAYYEEGTIRLVLEYMDQGSLRSIIQQIYKHNLSELINEQIIATITYNILMGLQYLH 187
Query: 204 DKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTH 261
+ +HRD+KP NIL+NS G+IK+ DFG+S QL + ++A +FVGT YMSPER +G +
Sbjct: 188 QQKHQLHRDIKPENILINSLGQIKLTDFGISKQLENTIAIARTFVGTLMYMSPERTEGKN 247
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
YS SDIWSLGL + EMA G +P S + M ++
Sbjct: 248 YSYASDIWSLGLIIYEMATGKHPYSV------------------------SNKQMTYIQM 283
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFV--------DRCLKKNPDERADLKTLMNHEWIRKAE 373
+ I+ PKL + +S E +DFV D L K+ +R D +TL+ H WI K
Sbjct: 284 IQNILKSESPKLDNYPYSVEMRDFVNIWQDLNIDFSLNKDQSKRLDAQTLLQHNWIIKNA 343
Query: 374 AEKVDIAGWV 383
+ W+
Sbjct: 344 QNSQYVQMWI 353
>UniRef50_UPI0000660B42 Cluster: Homolog of Homo sapiens
"Serine/threonine-protein kinase 4; n=1; Takifugu
rubripes|Rep: Homolog of Homo sapiens
"Serine/threonine-protein kinase 4 - Takifugu rubripes
Length = 510
Score = 165 bits (401), Expect = 2e-39
Identities = 89/217 (41%), Positives = 136/217 (62%), Gaps = 10/217 (4%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146
++ F+ L +LG+G+ G V K +K TG I+A K + +E + ++II+E+ ++ +CN
Sbjct: 18 EEVFDILEKLGEGSYGCVFKANYKETGEIVAIKEVPVE---SDLQEIIKEISIMQQCNSP 74
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
H+V +YG+++ D + I MEY GS+ D+I + + E + TI + LKGL YL
Sbjct: 75 HVVRYYGSYFKDSNLLIVMEYCGAGSVADIIRIRNKTLAEEEIATILQSTLKGLEYLHFM 134
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYS 263
I HRD+K NIL+N+ G+ K+ DFGV+GQL D+MA N+ +GT +M+PE +Q Y+
Sbjct: 135 RKI-HRDIKAGNILLNAEGQAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEIIQENGYN 193
Query: 264 VQSDIWSLGLSLVEMAIGMYP---IPPPDAKTLAAIF 297
+DIWSLG++ +EMA G P I P D L AIF
Sbjct: 194 CVADIWSLGITAIEMAEGKPPYADIHPMDCCVLQAIF 230
>UniRef50_Q8IGS1 Cluster: RE38276p; n=2; Drosophila
melanogaster|Rep: RE38276p - Drosophila melanogaster
(Fruit fly)
Length = 642
Score = 165 bits (400), Expect = 2e-39
Identities = 102/286 (35%), Positives = 160/286 (55%), Gaps = 33/286 (11%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F K +G+G+ G V K T ++A K+I LE I +E+ VL +C+ ++
Sbjct: 13 FTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIDDIQQEIMVLSQCDSPYVT 72
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+YG+F ++ I MEY+ GGS L L KAG E +G I VLKGL YL + +
Sbjct: 73 KYYGSFLKGTKLWIIMEYLGGGSA-LDLMKAGSFEEMHIGIILREVLKGLDYLHSERK-L 130
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTHYSVQSD 267
HRD+K +N+L++ G++K+ DFGV+GQL + S N+FVGT +M+PE ++ + Y ++D
Sbjct: 131 HRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDAKAD 190
Query: 268 IWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVN 327
IWSLG++ +E+A G PP+++ PM + L I
Sbjct: 191 IWSLGITAIELAKG----EPPNSEL---------------------HPMRVLFL---IPK 222
Query: 328 EPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
PP+L +G ++ FKDFV+ CL K+P+ R K L+ + +I+KA+
Sbjct: 223 NNPPQL-TGSYTKSFKDFVEACLNKDPENRPTAKELLKYPFIKKAK 267
>UniRef50_Q38B76 Cluster: Protein kinase, putative; n=1; Trypanosoma
brucei|Rep: Protein kinase, putative - Trypanosoma
brucei
Length = 378
Score = 163 bits (396), Expect = 7e-39
Identities = 108/285 (37%), Positives = 156/285 (54%), Gaps = 29/285 (10%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN--FAHIVGFYG 153
LG+G+ G V + H+ TG +A K I + + +I REL+ LH ++V FYG
Sbjct: 61 LGRGSSGSVRRATHRKTGKEIALKEIKFTGQTRMM-EIRRELETLHRGGGPSPYLVDFYG 119
Query: 154 AFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDV 213
AF +G + I ME MDG SLD + AG +P +L IT ++L+GLSYL ++HRD+
Sbjct: 120 AFCHEGSVFIAMECMDG-SLDGV---AGSVPPKVLECITRSILRGLSYLHKDRHLIHRDI 175
Query: 214 KPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTHYSVQSDIWSL 271
KPSNIL + +G IKI DFG S L + N SFVGT +YMSPERL+G YS +DIWSL
Sbjct: 176 KPSNILYSRDGSIKISDFGASSCLECTRGNAFSFVGTLTYMSPERLKGEPYSFPADIWSL 235
Query: 272 GLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPP 331
GL++ E+A+G P D + A G E + LL ++ + P
Sbjct: 236 GLAVAELALGKCPF--IDRLSRA---NGSTEG-------------CFWVLLQHLNGDGPV 277
Query: 332 -KLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAE 375
LPS + + DF+ C+++ P +R L H ++ + + E
Sbjct: 278 ISLPSSM-NASMTDFITTCIQREPSKRPTCDELRRHPFVAEGDEE 321
>UniRef50_O14305 Cluster: Serine/threonine-protein kinase sid1; n=1;
Schizosaccharomyces pombe|Rep: Serine/threonine-protein
kinase sid1 - Schizosaccharomyces pombe (Fission yeast)
Length = 471
Score = 163 bits (396), Expect = 7e-39
Identities = 113/295 (38%), Positives = 163/295 (55%), Gaps = 34/295 (11%)
Query: 85 LSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN 144
L+ + + L +LG G+ GVV K R +G I+A K I LE I +E+ +L CN
Sbjct: 4 LNANSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCN 63
Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRD 204
++++ +YG F + I ME+MDGGS+ +L K GR+ E ++ I VL GL+YL
Sbjct: 64 SSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLL-KMGRLNEQVISIILREVLYGLNYLHG 122
Query: 205 KHAIMHRDVKPSNILVNSN-GEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTH 261
++ I HRD+K +NIL++S+ G +K+ DFGV+ QL + S ++FVGT +M+PE +Q T
Sbjct: 123 QNKI-HRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTS 181
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
Y + +DIWSLG++ +EMA G IPP +A P IFE
Sbjct: 182 YGLAADIWSLGITAIEMANG---IPP--------------------RATMHPM-RVIFE- 216
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEK 376
I PPKL FS F+DFV CL NP+ R K L+ H +I+ A K
Sbjct: 217 ---IPQSEPPKLDDH-FSPTFRDFVSCCLDLNPNMRWSAKELLQHPFIKSAGTVK 267
>UniRef50_UPI0000E47F28 Cluster: PREDICTED: similar to Map2k3
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Map2k3 protein -
Strongylocentrotus purpuratus
Length = 360
Score = 163 bits (395), Expect = 1e-38
Identities = 84/207 (40%), Positives = 130/207 (62%), Gaps = 12/207 (5%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKV-LHECNFAH 147
D + LG+G G+V K RH+ T IMA K + +V K+I+ ++ V + + +
Sbjct: 52 DMIVIENLGRGAYGIVDKTRHEPTESIMAVKKMRAQVNSTEDKRILMDMDVAMRSSDCVY 111
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-----IPESILGTITSAVLKGLSYL 202
V FYGA + +G++ ICME MD LD + K + +PE+IL I+ +++ L YL
Sbjct: 112 TVEFYGALFQEGDVWICMEVMDT-CLDKLYKNKLKPQKIFVPENILSRISFSIVSALKYL 170
Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYMSPER----L 257
+ + ++HRDVKPSN+L N NG+IK+CDFG+SGQL++SMA + G+R YM+PER +
Sbjct: 171 QTRLKVIHRDVKPSNVLANHNGKIKLCDFGISGQLVNSMAKTQDAGSRQYMAPERIDPDM 230
Query: 258 QGTHYSVQSDIWSLGLSLVEMAIGMYP 284
Y V+SD+WS G++++E+A YP
Sbjct: 231 SAKGYDVKSDVWSFGITMIEIATNAYP 257
>UniRef50_O61122 Cluster: Severin kinase; n=2; Dictyostelium
discoideum|Rep: Severin kinase - Dictyostelium
discoideum (Slime mold)
Length = 478
Score = 161 bits (390), Expect = 4e-38
Identities = 104/281 (37%), Positives = 157/281 (55%), Gaps = 33/281 (11%)
Query: 95 ELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGA 154
++G+G+ G V K +K T +A K I LE + I +E+ VL +C + ++G+
Sbjct: 17 KIGKGSFGEVFKGINKKTNETIAIKTIDLEDAEDEIEDIQQEINVLSQCESPFVTKYFGS 76
Query: 155 FYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVK 214
F ++ I MEY+ GGS+ L L K G E + I +LKGL YL + I HRD+K
Sbjct: 77 FLKGSKLWIIMEYLAGGSV-LDLMKPGPFDEGYIAIILRELLKGLEYLHSEGKI-HRDIK 134
Query: 215 PSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQSDIWSLG 272
+N+L++++G++K+ DFGVSGQL D M N+FVGT +M+PE ++ T Y ++DIWS+G
Sbjct: 135 AANVLLSASGDVKLADFGVSGQLTDQMTKRNTFVGTPFWMAPEVIKQTGYDSKADIWSMG 194
Query: 273 LSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPK 332
++ +EMA G PP A D P +A L I +PPP
Sbjct: 195 ITALEMAKG----EPPRA------------DLHPMRA------------LFLIPKDPPPT 226
Query: 333 LPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
L G FS FK+F CL K+P++R K L+ H++I+ A+
Sbjct: 227 L-EGNFSKGFKEFCALCLNKDPNQRPTAKDLLKHKFIKAAK 266
>UniRef50_Q20347 Cluster: MAP kinase kinase mkk-4; n=4;
Rhabditida|Rep: MAP kinase kinase mkk-4 - Caenorhabditis
elegans
Length = 363
Score = 160 bits (388), Expect = 7e-38
Identities = 88/214 (41%), Positives = 133/214 (62%), Gaps = 10/214 (4%)
Query: 80 EKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE-VKPAIKKQIIRELK 138
E + S + + LG +G GN G V K+RHK TG ++A K I + + +++RE
Sbjct: 56 EHLYTFSSANLQDLGAIGNGNFGTVYKMRHKETGKLIAVKRIRCNNIGHREQIRLLREHD 115
Query: 139 VLHECNFA-HIVGFYGAFYSDGEISICMEYMDGGSLDLILK-----KAGRIPESILGTIT 192
+ + +IV FYGA +S+G+ ICME MD S+DL+ K K R+ E+++G IT
Sbjct: 116 TIVKSEKGPNIVKFYGAIFSEGDCWICMELMDI-SMDLLYKRVYMVKNSRLNENVVGHIT 174
Query: 193 SAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSF-VGTRSY 251
+ L YL+ + I+HRDVKPSNILV+ G +K+CDFG+ GQL +S A + G + Y
Sbjct: 175 VCTVDALDYLKKELKIIHRDVKPSNILVDGTGAVKLCDFGICGQLEESFAKTHDAGCQPY 234
Query: 252 MSPERLQGT-HYSVQSDIWSLGLSLVEMAIGMYP 284
++PER+ + Y V+SD+WSLG++L E+A G +P
Sbjct: 235 LAPERITSSDKYDVRSDVWSLGITLYEIATGKFP 268
>UniRef50_Q9Y6E0 Cluster: Serine/threonine-protein kinase 24; n=138;
Eumetazoa|Rep: Serine/threonine-protein kinase 24 - Homo
sapiens (Human)
Length = 443
Score = 159 bits (387), Expect = 9e-38
Identities = 103/283 (36%), Positives = 160/283 (56%), Gaps = 35/283 (12%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F KL ++G+G+ G V K T ++A K+I LE + I +E+ VL +C+ ++
Sbjct: 36 FTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVT 95
Query: 150 GFYGAFYSDGEISICMEYMDGGS-LDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+YG++ D ++ I MEY+ GGS LDL+ + G + E+ + TI +LKGL YL + I
Sbjct: 96 KYYGSYLKDTKLWIIMEYLGGGSALDLL--EPGPLDETQIATILREILKGLDYLHSEKKI 153
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPERLQGTHYSVQS 266
HRD+K +N+L++ +GE+K+ DFGV+GQL D+ N+FVGT +M+PE ++ + Y ++
Sbjct: 154 -HRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKA 212
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
DIWSLG++ +E+A G PP +E H PM + L I
Sbjct: 213 DIWSLGITAIELARG----EPP-----------HSELH----------PMKVLFL---IP 244
Query: 327 NEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
PP L G +S K+FV+ CL K P R K L+ H++I
Sbjct: 245 KNNPPTL-EGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFI 286
>UniRef50_A0EBN0 Cluster: Chromosome undetermined scaffold_88, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_88,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 377
Score = 159 bits (385), Expect = 2e-37
Identities = 109/308 (35%), Positives = 160/308 (51%), Gaps = 50/308 (16%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVL------------HEC 143
LG+G G V + +K G+ +A K I+ + + Q++ ++K+L + C
Sbjct: 71 LGRGAAGTVSEAIYKPLGIRVAIKSINAYDREK-RYQLMNDIKILLHNKMNAENNSGYYC 129
Query: 144 NFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILK--KAGRI-----PESILGTITSAVL 196
F +V YGA++ +G + + +E MD GSL IL+ +A +I E IL I+ +L
Sbjct: 130 QF--LVNLYGAYFDEGSVKVVLELMDAGSLGDILRIYRAAQINGPIISEPILAKISQQIL 187
Query: 197 KGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS-MANSFVGTRSYMSPE 255
GLSYL +HRD+KP NIL+NS G +K+ DFG+S L S + GT++YMSPE
Sbjct: 188 NGLSYLHLISNQIHRDIKPDNILLNSQGYVKLTDFGISRDLEQSAFCTTNCGTQAYMSPE 247
Query: 256 RLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRP 315
R+ Y+ SDIWS G+ L E+A+G YP AKT
Sbjct: 248 RIGAKKYNHLSDIWSFGIVLYELAMGKYPF--SSAKT----------------------- 282
Query: 316 MAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAE 375
FE+LD +VNE P+L FS E KDF+ RCL+K RA L++H WI + +
Sbjct: 283 --YFEMLDAVVNEAQPELSGNQFSPELKDFLTRCLQKKISMRASAVELLSHPWILQNFNK 340
Query: 376 KVDIAGWV 383
I+ W+
Sbjct: 341 GESISDWL 348
>UniRef50_Q5KD75 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 727
Score = 157 bits (382), Expect = 4e-37
Identities = 107/313 (34%), Positives = 167/313 (53%), Gaps = 36/313 (11%)
Query: 93 LGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFY 152
L +LG GN G V K H T I+A K+I LE +I E+ L C H+ +Y
Sbjct: 20 LEKLGAGNFGTVWKASHNDTKQIVAIKMIDLESSDDDISEIQAEIAHLSSCWSDHVTKYY 79
Query: 153 GAFYSDGEISICMEYMDGGS-LDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHR 211
G+F + I MEY+ GGS LDL+ K G E+ + + +L GL YL + I HR
Sbjct: 80 GSFVRGARLWIVMEYLAGGSCLDLL--KPGVFTEAQIAIVCRELLLGLEYLHMEGKI-HR 136
Query: 212 DVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTHYSVQSDIW 269
D+K +N+L++++G++K+ DFGV+ QL S ++FVGT +M+PE ++ Y ++DIW
Sbjct: 137 DIKAANVLLSASGDVKLADFGVAAQLSSHKSQRHTFVGTPFWMAPEVIRQAGYDSRADIW 196
Query: 270 SLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEP 329
SLG++ +EMA G P+ +E H PM + L+
Sbjct: 197 SLGITAIEMAKGDPPL---------------SEYH----------PMRVLFLIPKA--RA 229
Query: 330 PPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGWVCKTMDL 389
P P +S+EF+DF+++CL+K+P +RA K L+ H +IR A+ + D+ + +
Sbjct: 230 PTLDPEEGWSEEFQDFIEKCLQKDPRDRATAKQLLQHRFIRSAK-KTTDLIPLITRYQSY 288
Query: 390 MPSTPNS--NVSP 400
S P+S N +P
Sbjct: 289 KSSHPSSKPNTTP 301
>UniRef50_Q871H9 Cluster: Related to Ste20-like kinase Don3; n=2;
Sordariales|Rep: Related to Ste20-like kinase Don3 -
Neurospora crassa
Length = 829
Score = 157 bits (381), Expect = 5e-37
Identities = 105/286 (36%), Positives = 158/286 (55%), Gaps = 35/286 (12%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
++ L ELG+G+ GVV K K+TG +A K I LE ++I +E+ VL C +++
Sbjct: 10 YQVLEELGRGSFGVVYKGIDKTTGETVAIKHIDLESSEDDIQEIQQEISVLSTCASSYVT 69
Query: 150 GFYGAFYSDGEISICMEYMDGGS-LDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+ +F ++ I ME++ GGS LDL+ K G E + + +L GL YL + I
Sbjct: 70 QYKASFLRGHKLWIVMEFLGGGSCLDLL--KPGNFSEVHIAIVCRELLLGLDYLHSEGKI 127
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQL--IDSMANSFVGTRSYMSPERLQGTHYSVQS 266
HRD+K +N+L++ G++K+ DFGV+ QL + S N+FVGT +M+PE +Q Y ++
Sbjct: 128 -HRDIKAANVLLSEAGKVKLADFGVAAQLTHMKSQRNTFVGTPFWMAPEVIQQAGYDFKA 186
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
DIWSLG++ +E+A+G PP A PM ++L I
Sbjct: 187 DIWSLGITAIELAVG----EPPYANI---------------------HPM---KVLFQIP 218
Query: 327 NEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
PPP+L G FS EFKDFV CL K+P +R + L+ H +IR A
Sbjct: 219 KNPPPRL-EGKFSREFKDFVAHCLIKDPAQRPTARDLLRHRFIRTA 263
>UniRef50_Q9UAH1 Cluster: JKK-1; n=2; Caenorhabditis|Rep: JKK-1 -
Caenorhabditis elegans
Length = 435
Score = 157 bits (380), Expect = 6e-37
Identities = 98/282 (34%), Positives = 149/282 (52%), Gaps = 34/282 (12%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
LG G+ GVV +S +MA K ++ K+I+R+++++ CN IV YG F
Sbjct: 128 LGSGSCGVVESATVRSK--LMAVKTMYKNDNKENLKRILRDVRIMSMCNSPFIVTSYGYF 185
Query: 156 YSDGEISICMEYMDGGSLDLILK----KAGRIPESILGTITSAVLKGLSYLRDKHAIMHR 211
D + ICM+ M L+ + K PE + G I + + L YL++KH+I+HR
Sbjct: 186 MFDSSVKICMQIMSACCEKLLRRIYHSKLDFFPEFVAGHIVYSAISALDYLKEKHSIIHR 245
Query: 212 DVKPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYMSPERL---QGTHYSVQSD 267
D+KPSNIL + +G +K+CDFG+SG + DSMA+S G YM+PERL + Y V+SD
Sbjct: 246 DIKPSNILFDDSGNVKLCDFGISGFMTDSMAHSKSAGCPPYMAPERLTIETNSKYDVRSD 305
Query: 268 IWSLGLSLVEMAIGMYPIPPPDAK-TLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
+WSLG+++ ++ G+YP P D + T I N SP + R
Sbjct: 306 VWSLGITVYQLVTGLYPFPLNDMEFTTLTIIANLNLP-SPSLREETKRS----------- 353
Query: 327 NEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEW 368
FS F +F+D CL+K+ ER + + LM H++
Sbjct: 354 -----------FSPLFIEFLDLCLRKDVRERPEYRQLMKHDF 384
>UniRef50_Q8NJX3 Cluster: Ste20-like kinase Don3; n=2; Ustilago
maydis|Rep: Ste20-like kinase Don3 - Ustilago maydis
(Smut fungus)
Length = 839
Score = 157 bits (380), Expect = 6e-37
Identities = 109/295 (36%), Positives = 165/295 (55%), Gaps = 40/295 (13%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
ELS+ +E L ++G G+ G V K HK + I+A K + LE +I +E+ L +C
Sbjct: 77 ELSEQ-YELLEKIGAGSFGTVYKAMHKQSRQIVAIKQVDLEDSDDDISEIQQEIAHLAQC 135
Query: 144 NFAHIVGFYGAFYSDGEISICMEYMDGGS-LDLILKKAGRIPESILGTITSAVLKGLSYL 202
+ + +YG+F ++ I MEY+ GGS LDL+ KAG E+ + I +L GL YL
Sbjct: 136 DSQWVTRYYGSFVKGYKLWIIMEYLAGGSCLDLL--KAGSFSEAHIAIICRELLLGLEYL 193
Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGT 260
++ I HRD+K +N+L++++G++K+ DFGV+ QL + S N+FVGT +M+PE ++
Sbjct: 194 HNEGKI-HRDIKAANVLLSASGKVKLADFGVAAQLSNNKSRRNTFVGTPFWMAPEVIRQA 252
Query: 261 HYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFE 320
Y ++DIWSLG++ +EMA G PP A E H PM +
Sbjct: 253 GYDYKADIWSLGITAIEMAKG----EPPLA-----------EYH----------PMRVLF 287
Query: 321 LLDYIVNEPPPKLPS--GIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
L+ P K P+ G FS FKDFVD CL K+P R K L++H +I+ A+
Sbjct: 288 LI------PKAKSPTLQGNFSSAFKDFVDLCLIKDPKHRPSTKELLSHRFIKYAK 336
>UniRef50_A2R1E1 Cluster: Contig An13c0040, complete genome; n=4;
Eurotiomycetidae|Rep: Contig An13c0040, complete genome
- Aspergillus niger
Length = 684
Score = 156 bits (378), Expect = 1e-36
Identities = 103/281 (36%), Positives = 157/281 (55%), Gaps = 35/281 (12%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
+G G+ G V K K TG +A K+I +E + II+E+ +L E N ++ ++G+F
Sbjct: 17 IGGGSFGRVYKGVDKRTGASVAIKIIDVENAEDEVEDIIQEIAILSELNSPYVTRYHGSF 76
Query: 156 YSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLR-DKHAIMHRDVK 214
+ I ME+ GGS L + G IPE + I +L+GL YL DK +HRDVK
Sbjct: 77 LKGSSLWIIMEFCSGGSCS-DLMRPGTIPEEYIMIIIRELLRGLDYLHSDKK--LHRDVK 133
Query: 215 PSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQSDIWSLG 272
+NIL+ SNG++K+ DFGVS QL +M N+FVGT +M+PE ++ + Y ++DIWSLG
Sbjct: 134 AANILLTSNGQVKLADFGVSSQLSATMTKKNTFVGTPFWMAPEVIKQSGYDYKADIWSLG 193
Query: 273 LSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPK 332
++ +E+A G PP ++ H PM + L I PPP
Sbjct: 194 ITAIELANG----EPP-----------YSDIH----------PMKVLFL---IPKNPPPV 225
Query: 333 LPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
L G +S FK+FV+ CL+++P ER + L+ H +I++A+
Sbjct: 226 L-QGDYSKAFKNFVELCLRRDPRERPSARELLEHPFIKRAK 265
>UniRef50_A2F5W2 Cluster: STE family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: STE family protein kinase
- Trichomonas vaginalis G3
Length = 362
Score = 155 bits (377), Expect = 1e-36
Identities = 113/360 (31%), Positives = 177/360 (49%), Gaps = 39/360 (10%)
Query: 29 MTPQLKSATANERQGLAGKSKTSIEALTERLEQIEMDDTQRRRIEVFLCQKE-KIGELSD 87
+ P+L + + +G + + EA R E + + + R L +E + L+D
Sbjct: 13 VVPKLDNDSPGYYKGTSSFESENFEAEIIR-ESADYGELKLRSDGTILFSQEYPVVTLAD 71
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQI--IRELKVLHECNF 145
F + +LG G G V + H +G A K I + K ++K + I L++L N
Sbjct: 72 LKFHE--QLGHGVQGTVYRCTHIPSGKEFAVKSIKYQDKSQLQKTVDEIHSLRILRHPNV 129
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
H+ + AF G I I M+ ++G SL LK + IPE L IT ++ GL +
Sbjct: 130 VHL---FSAFAQKGSIHILMDLVNGASLGDYLKYSPIIPEPALHEITVQMIAGLRFCCKN 186
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYS 263
H I+HRD+KPSN++++ +G I+I DFG++ QL D+ A S +GT YMSPER++G Y
Sbjct: 187 H-IIHRDIKPSNVMLSLDGRIQIADFGLARQLRDTGDFAQSVIGTTCYMSPERIRGQSYG 245
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLD 323
++SD+WSLGL L + IG YP G+N+ H FE +
Sbjct: 246 LKSDVWSLGLILYQSCIGRYPF-------------GENKTHFWD---------LNFETQN 283
Query: 324 YIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGWV 383
I+ + P +S DF+++CL D+RA + L HEWI K ++ W+
Sbjct: 284 DIIVDLGPN-----YSPLLLDFIEKCLVMEQDDRATFEELNAHEWITNGSGSKDELVKWI 338
>UniRef50_A1DC98 Cluster: Ste20-like serine/threonine protein
kinase, putative; n=4; Trichocomaceae|Rep: Ste20-like
serine/threonine protein kinase, putative - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 688
Score = 155 bits (376), Expect = 2e-36
Identities = 103/280 (36%), Positives = 157/280 (56%), Gaps = 35/280 (12%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
+G G+ G V K K TG +A K+I +E + II+E+ +L E + ++ ++G+F
Sbjct: 17 IGGGSFGRVYKGVDKRTGNSVAIKVIDVENAEDEVEDIIQEIAILSELDSPYVTKYHGSF 76
Query: 156 YSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLR-DKHAIMHRDVK 214
+ I ME+ GGS +L+ G IPE + I +L+GL YL DK +HRDVK
Sbjct: 77 LKGSHLWIVMEFCSGGSCSDLLRP-GPIPEDYIMIIMRELLRGLDYLHTDKK--LHRDVK 133
Query: 215 PSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQSDIWSLG 272
+NIL+ SNG++K+ DFGVS QL +M N+FVGT +M+PE ++ + Y ++DIWSLG
Sbjct: 134 AANILLTSNGQVKLADFGVSSQLSATMTKKNTFVGTPFWMAPEVIKQSGYDYKADIWSLG 193
Query: 273 LSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPK 332
++ +E+A G PP ++ H PM + L I PPP
Sbjct: 194 ITAIELAQG----EPP-----------YSDIH----------PMKVLFL---IPKNPPPT 225
Query: 333 LPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
L G FS FK+FV+ CL+++P ER K L+ H ++++A
Sbjct: 226 L-QGPFSKTFKNFVELCLRRDPRERPSAKELLEHPFVKRA 264
>UniRef50_Q7Q155 Cluster: ENSANGP00000022332; n=6;
Endopterygota|Rep: ENSANGP00000022332 - Anopheles
gambiae str. PEST
Length = 635
Score = 154 bits (374), Expect = 3e-36
Identities = 99/286 (34%), Positives = 158/286 (55%), Gaps = 33/286 (11%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F K +G+G+ G V K T ++A K+I LE + I +E+ VL +C+ +
Sbjct: 12 FTKQERIGKGSFGEVFKGVDNRTQQVVAIKIIDLEEAEDEIEDIQQEIMVLSQCDSPFVT 71
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
++G++ ++ I MEY+ GGS L L KAG E + I VLKGL YL + +
Sbjct: 72 KYFGSYLKGTKLWIIMEYLGGGSA-LDLMKAGLFEEMHIAIILREVLKGLDYLHSERK-L 129
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTHYSVQSD 267
HRD+K +N+L++ G++K+ DFGV+GQL + S N+FVGT +M+PE ++ + Y ++D
Sbjct: 130 HRDIKAANVLLSELGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVIKQSMYDSKAD 189
Query: 268 IWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVN 327
IWSLG++ +E+A G PP+++ PM + L I
Sbjct: 190 IWSLGITAIELAKG----EPPNSEL---------------------HPMRVLFL---IPK 221
Query: 328 EPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
PP+L +G ++ FKDFV+ CL K+P+ R K L+ +I+KA+
Sbjct: 222 NNPPQL-TGSYTKPFKDFVEACLNKDPENRPTAKELLKFPFIKKAK 266
>UniRef50_Q4QEZ0 Cluster: Protein kinase, putative; n=3;
Leishmania|Rep: Protein kinase, putative - Leishmania
major
Length = 631
Score = 154 bits (374), Expect = 3e-36
Identities = 79/199 (39%), Positives = 127/199 (63%), Gaps = 5/199 (2%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHL-EVKPAIKKQIIRELKVLHECNFAHI 148
FE + +G GN GVV+K R+++T I+A K + L + I++E+++L EC+ +I
Sbjct: 21 FEIIESVGIGNFGVVLKARNRATEDIVAIKQVPLSDTDKEDLDTIVKEVEILQECDHPNI 80
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKHA 207
V FYG +YS G + I MEY +GGS+D R + E ++ + L GL YL ++H
Sbjct: 81 VRFYGTYYSMGVLWIVMEYCEGGSVDTAYDLLRRPLSEPLIAYVCRQTLLGLRYLHERH- 139
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQ 265
++HRD+K SN+L+ NG++K+ DFGVS +L +++ NSF+GT +M+PE L Y +
Sbjct: 140 VIHRDIKGSNLLLTKNGQVKLADFGVSTELKHTLSRRNSFIGTALWMAPEALTEKDYDSR 199
Query: 266 SDIWSLGLSLVEMAIGMYP 284
+D+WSLG++ +E+A G P
Sbjct: 200 ADMWSLGITTIELAEGQPP 218
>UniRef50_UPI00015551F0 Cluster: PREDICTED: similar to
Serine/threonine kinase 3 (STE20 homolog, yeast); n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
Serine/threonine kinase 3 (STE20 homolog, yeast) -
Ornithorhynchus anatinus
Length = 557
Score = 154 bits (373), Expect = 5e-36
Identities = 82/217 (37%), Positives = 137/217 (63%), Gaps = 12/217 (5%)
Query: 76 LCQKEKIGELS-----DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIK 130
+C+ +K+ E S ++ F+ L +LG+G+ G V K HK +G ++A K + +E +
Sbjct: 226 ICKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVE---SDL 282
Query: 131 KQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILG 189
++II+E+ ++ +C+ ++V +YG+++ + ++ I MEY GS+ D+I + + E +
Sbjct: 283 QEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIA 342
Query: 190 TITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVG 247
TI + LKGL YL I HRD+K NIL+N+ G K+ DFGV+GQL D+MA N+ +G
Sbjct: 343 TILKSTLKGLEYLHFMRKI-HRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIG 401
Query: 248 TRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284
T +M+PE +Q Y+ +DIWSLG++ +EMA G P
Sbjct: 402 TPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPP 438
>UniRef50_Q5KDT4 Cluster: Serine/threonine protein kinase MST4,
putative; n=1; Filobasidiella neoformans|Rep:
Serine/threonine protein kinase MST4, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 517
Score = 153 bits (371), Expect = 8e-36
Identities = 98/285 (34%), Positives = 155/285 (54%), Gaps = 33/285 (11%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+ + +G+G+ G V + K T L +A K+I LE I +E+++L + + +
Sbjct: 20 YVRQNRIGKGSFGEVYQGYDKRTSLPVAIKIIDLESAEDEIDDIQQEIQILSQLDSEFVT 79
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
++G+F + I MEY GGS ++K AG E + + +L+GL YL ++ +
Sbjct: 80 RYHGSFLKGSHLWIIMEYCSGGSCSDLMK-AGVFKEEYIAILARELLRGLEYLHEEGKL- 137
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQSD 267
HRD+K +NIL+ +NG++K+ DFGVSGQL +M N+FVGT +MSPE ++ + Y ++D
Sbjct: 138 HRDIKAANILLTANGDVKLADFGVSGQLTATMTKKNTFVGTPYWMSPEVIKQSGYDHKAD 197
Query: 268 IWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVN 327
IWSLG++ +EMA+G PP A PM + L I
Sbjct: 198 IWSLGITCIEMAMG----EPPYADL---------------------HPMKVLFL---IPK 229
Query: 328 EPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
PPP+L FS F+DFV CL+++P R K L+ H++I+ A
Sbjct: 230 NPPPQLDDR-FSRPFRDFVSLCLQRDPRNRPTAKELLKHKFIKTA 273
>UniRef50_Q0UWD5 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 946
Score = 152 bits (369), Expect = 1e-35
Identities = 101/285 (35%), Positives = 155/285 (54%), Gaps = 33/285 (11%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F K +G G+ G V K + TG +A K+I +E + I+ E+ +L + ++
Sbjct: 202 FTKQECIGGGSFGKVYKGLDRRTGHTVAIKVIDVENAEDEVEDIMGEIMILSGMSSPYVT 261
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+YG++ ++ I ME+ GGS L K G I E+ + + +L+GL YL D +
Sbjct: 262 RYYGSYLHGSDLWIVMEFCSGGSC-ADLMKPGLIAEAEIAVVVKELLQGLMYLHDDGKL- 319
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQSD 267
HRD+K +NILV +NG++K+ DFGVSGQL +M N+FVGT +M+PE ++ + Y ++D
Sbjct: 320 HRDIKAANILVGANGQVKLADFGVSGQLSATMTKKNTFVGTPFWMAPEVIKQSGYDGKAD 379
Query: 268 IWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVN 327
IWSLG++ +E+A G PP A PM + L I
Sbjct: 380 IWSLGITALELANG----EPPYADI---------------------HPMKVLFL---IPK 411
Query: 328 EPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
PPP+L G FS FK+F++ CL+K+P ER K L+ ++RKA
Sbjct: 412 NPPPQL-QGNFSPAFKEFIELCLRKDPRERPTAKQLLQCNFVRKA 455
>UniRef50_O80397 Cluster: Mitogen-activated protein kinase kinase 4;
n=23; Magnoliophyta|Rep: Mitogen-activated protein
kinase kinase 4 - Arabidopsis thaliana (Mouse-ear cress)
Length = 366
Score = 152 bits (369), Expect = 1e-35
Identities = 98/291 (33%), Positives = 152/291 (52%), Gaps = 38/291 (13%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148
D + +G G GG V KV H+ + + A K+I+ + +++QI RE+++L + N ++
Sbjct: 78 DLVRGNRIGSGAGGTVYKVIHRPSSRLYALKVIYGNHEETVRRQICREIEILRDVNHPNV 137
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
V + F +GEI + +E+MD GSL+ A E L ++ +L GL+YL +H I
Sbjct: 138 VKCHEMFDQNGEIQVLLEFMDKGSLE----GAHVWKEQQLADLSRQILSGLAYLHSRH-I 192
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPERL-----QGTH 261
+HRD+KPSN+L+NS +KI DFGVS L +M NS VGT +YMSPER+ QG +
Sbjct: 193 VHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLNQGKY 252
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
DIWSLG+S++E +G +P P A++ P +AP + P
Sbjct: 253 DGYAGDIWSLGVSILEFYLGRFPFPVSRQGDWASLMCAICMSQPP-EAPATASP------ 305
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
EF+ F+ CL++ P +R L+ H +I +A
Sbjct: 306 -------------------EFRHFISCCLQREPGKRRSAMQLLQHPFILRA 337
>UniRef50_Q21307 Cluster: Map kinase kinase or erk kinase protein 1,
isoform a; n=3; Caenorhabditis|Rep: Map kinase kinase or
erk kinase protein 1, isoform a - Caenorhabditis elegans
Length = 347
Score = 152 bits (368), Expect = 2e-35
Identities = 101/298 (33%), Positives = 160/298 (53%), Gaps = 36/298 (12%)
Query: 95 ELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLH-ECNFAHIVGFYG 153
++G G+ G V K R+KS +IMA K + +I+ +L V+ + +IV +G
Sbjct: 77 DIGHGSCGTVTKCRYKS--VIMAVKTMPRTSNSYEMSRILMDLDVICLSFDCPYIVRCFG 134
Query: 154 AFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDV 213
F ++ ++ +CME M L+++ IPE I+G ++ +++K L YL+ KH IMHRDV
Sbjct: 135 YFITNFDVRVCMECMATCLDRLLIRIKQPIPERIIGKLSVSIIKALHYLKTKHQIMHRDV 194
Query: 214 KPSNILVNSNGEIKICDFGVSGQLIDSMANS-FVGTRSYMSPERLQGTH---YSVQSDIW 269
KPSNIL++ +G IK+CDFG++G+LI+S A+S G YM PERL + Y ++SD+W
Sbjct: 195 KPSNILLDWSGVIKLCDFGIAGRLIESRAHSKQAGCPLYMGPERLDPNNFDSYDIRSDVW 254
Query: 270 SLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEP 329
S G++LVE+A G YP + ++ I + PR LD
Sbjct: 255 SFGVTLVELATGQYPYAGTEFDMMSKILNDE-----------PPR-------LD------ 290
Query: 330 PPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGWVCKTM 387
P K FS +F V+ CL+++P R + L+ H ++ E + D+ W M
Sbjct: 291 PAK-----FSPDFCQLVESCLQRDPTMRPNYDMLLQHPFVVHHEKIETDVEEWFADVM 343
>UniRef50_Q4DPN9 Cluster: Protein kinase, putative; n=3;
Trypanosoma|Rep: Protein kinase, putative - Trypanosoma
cruzi
Length = 474
Score = 151 bits (365), Expect = 4e-35
Identities = 81/198 (40%), Positives = 125/198 (63%), Gaps = 5/198 (2%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+E+LG +G GN G V+K R++ T I A KL+ L K + + +E+ +L +C +IV
Sbjct: 21 YEELGPIGVGNYGSVIKARNRQTQAIAAIKLVLLVDKDE-RDFVQKEISILKKCVHPNIV 79
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKHAI 208
+YGA S ++ I MEY +GGS+D++ K +PE+++ + VL GL YL I
Sbjct: 80 RYYGAHKSLSKLWIVMEYCEGGSVDMVYKVLRHPLPENLIAYVCRQVLLGLQYLHANRKI 139
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQS 266
HRD+K NIL+ +G++K+ DFGVS +L S++ N+FVGT +MSPE + Y ++
Sbjct: 140 -HRDIKGGNILLTRDGDVKLADFGVSTELSHSLSRRNTFVGTLLWMSPEAILELDYDEKA 198
Query: 267 DIWSLGLSLVEMAIGMYP 284
D+WSLG++L+EMA G P
Sbjct: 199 DLWSLGITLIEMAEGAPP 216
>UniRef50_O14047 Cluster: Serine/threonine-protein kinase ppk11;
n=5; Ascomycota|Rep: Serine/threonine-protein kinase
ppk11 - Schizosaccharomyces pombe (Fission yeast)
Length = 312
Score = 151 bits (365), Expect = 4e-35
Identities = 98/284 (34%), Positives = 148/284 (52%), Gaps = 31/284 (10%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+ L +GQG+ G V + + + I+A K++ L+ + + +E+ L + N HI
Sbjct: 6 YRDLQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHIT 65
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+Y +F + I MEY DGGS +LK +G E ++ + VL+ L YL + M
Sbjct: 66 KYYASFVDGFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQ-GKM 124
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQL--IDSMANSFVGTRSYMSPERLQGTHYSVQSD 267
HRD+K +NIL +G +K+ DFGVSGQL + + FVGT +M+PE ++ T Y+ ++D
Sbjct: 125 HRDIKAANILTMKDGLVKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVVKQTGYNYKAD 184
Query: 268 IWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVN 327
IWSLG++ E+A G PP + G + PM + L I
Sbjct: 185 IWSLGITAYELATG----EPP--------YSGIH-------------PMKVLLL---IPK 216
Query: 328 EPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
PP L FS F DFV CLKKNP +RA + L H++I+K
Sbjct: 217 HSPPSLERSKFSRAFCDFVSNCLKKNPKDRATAEYLSKHKFIKK 260
>UniRef50_Q9LDN6 Cluster: MAP kinase; n=18; Magnoliophyta|Rep: MAP
kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 690
Score = 150 bits (364), Expect = 6e-35
Identities = 101/286 (35%), Positives = 158/286 (55%), Gaps = 33/286 (11%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F ++ +G+G+ G V K K +A K+I LE + I +E+ VL +C +I
Sbjct: 15 FSQIELIGRGSFGDVYKAFDKDLNKEVAIKVIDLEESEDEIEDIQKEISVLSQCRCPYIT 74
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+YG++ ++ I MEYM GGS+ +L+ + E+ + IT +L + YL ++ I
Sbjct: 75 EYYGSYLHQTKLWIIMEYMAGGSVADLLQSNNPLDETSIACITRDLLHAVEYLHNEGKI- 133
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTH-YSVQS 266
HRD+K +NIL++ NG++K+ DFGVS QL +++ +FVGT +M+PE +Q + Y+ ++
Sbjct: 134 HRDIKAANILLSENGDVKVADFGVSAQLTRTISRRKTFVGTPFWMAPEVIQNSEGYNEKA 193
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
DIWSLG++++EMA G PP LA + PM + L I
Sbjct: 194 DIWSLGITVIEMAKG----EPP----LADL-----------------HPMRV---LFIIP 225
Query: 327 NEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
E PP+L FS + K+FV CLKK P ER K L+ H +I+ A
Sbjct: 226 RETPPQLDEH-FSRQVKEFVSLCLKKAPAERPSAKELIKHRFIKNA 270
>UniRef50_Q6C3K8 Cluster: Similar to DEHA0C16181g Debaryomyces
hansenii; n=1; Yarrowia lipolytica|Rep: Similar to
DEHA0C16181g Debaryomyces hansenii - Yarrowia lipolytica
(Candida lipolytica)
Length = 893
Score = 149 bits (360), Expect = 2e-34
Identities = 87/252 (34%), Positives = 148/252 (58%), Gaps = 12/252 (4%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA--- 146
+++ +G+GN GVV K HK T ++A K+++L+ K++ E+++L + A
Sbjct: 34 YQRQEVIGRGNFGVVYKGYHKKTKQLVAIKVLNLDTAEDDVKEVQHEIQLLSQLKLADAE 93
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
+I ++G++ + I MEY GGS+ ++K AGRI E L IT +L + Y+ K
Sbjct: 94 NITRYHGSYLHGSRLWIIMEYCAGGSVRTLMK-AGRIEERHLSVITRELLIAIQYMH-KA 151
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL-QGTHYS 263
I+HRD+K +NIL+ G +++CDFGV+ QL+ S ++ VGT +M+PE + +G Y+
Sbjct: 152 GIIHRDIKAANILITQQGRVQLCDFGVAAQLVSSKTKRSTIVGTPYWMAPEVITEGASYN 211
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLD 323
V++DIWSLG++L E+A G P+ D + + AIF + P + S A+ E++
Sbjct: 212 VKADIWSLGITLYEIATGSPPL--SDQEAMRAIF--LIPRNKPARLEGSQYSAALKEIVA 267
Query: 324 YIVNEPPPKLPS 335
++E P + PS
Sbjct: 268 LCLDELPDERPS 279
>UniRef50_Q0V1V7 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 636
Score = 148 bits (358), Expect = 3e-34
Identities = 90/220 (40%), Positives = 124/220 (56%), Gaps = 39/220 (17%)
Query: 162 SICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVN 221
+I M+ GGS+D + +PE +L IT A +GL L+D+H I+HRDVKP+NIL+N
Sbjct: 354 AIIMDSWTGGSIDKLYGDG--VPEGVLRKITLATTQGLKSLKDEHNIIHRDVKPTNILMN 411
Query: 222 SNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQ------------GTHYSVQSDIW 269
+ G+IKICDFGVSG L+ S+A + +G +SYM+PER+ G YSVQSDIW
Sbjct: 412 TKGQIKICDFGVSGNLVASIAKTNIGCQSYMAPERISSGGIAQAGANPGGGTYSVQSDIW 471
Query: 270 SLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEP 329
SLGL+++E A+G YP PP +T IF +L + EP
Sbjct: 472 SLGLTIIECALGCYPYPP---ETYNNIFS---------------------QLSAIVDGEP 507
Query: 330 PPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
P P G +SD ++FV CL K P+ R L+ H W+
Sbjct: 508 PDLPPEG-YSDAARNFVRGCLHKIPNLRPTYAMLLQHAWL 546
>UniRef50_UPI00006A0B9B Cluster: Mitogen-activated protein kinase
kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase
kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)
(Hematopoietic progenitor kinase).; n=1; Xenopus
tropicalis|Rep: Mitogen-activated protein kinase kinase
kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase
kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic
progenitor kinase). - Xenopus tropicalis
Length = 674
Score = 147 bits (355), Expect = 7e-34
Identities = 96/288 (33%), Positives = 154/288 (53%), Gaps = 34/288 (11%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
DDFE + LG G+ G V K R+K+TG + A K++ E I +E+ ++ C+ +
Sbjct: 13 DDFELIQRLGSGSYGEVFKARNKATGELAAVKIVTKEPDEDFSV-IQQEVLIVKSCSQKN 71
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
IV +YG++ + ++ ICMEY GGSL I + G + E + L+GLSYL ++
Sbjct: 72 IVAYYGSYMQENKLWICMEYCGGGSLQDIYQVTGALSELQTAYVCRETLQGLSYLHNQGK 131
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPE----RLQGTH 261
I HRD+K +NIL+N NG++K+ DFG+S QL + A SF+GT +M+PE L+G
Sbjct: 132 I-HRDIKGANILLNDNGDVKVADFGISAQLTATFARRKSFIGTPYWMAPEVAAVELKG-G 189
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
Y+ D+WSLG++ +E+A + PP +F H P+ + L
Sbjct: 190 YTELCDVWSLGITAIELA----ELQPP-------MF------HI--------HPLRVLFL 224
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
+ +PP +S F +FV L K+P +R L++H+++
Sbjct: 225 MSKSGFQPPKLKEKSKWSASFHNFVKAALTKSPKKRPSASKLLSHQFV 272
>UniRef50_Q8MPS3 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 411
Score = 147 bits (355), Expect = 7e-34
Identities = 89/220 (40%), Positives = 132/220 (60%), Gaps = 16/220 (7%)
Query: 80 EKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARK---LIHLEVKPAIKKQIIR- 135
++I E D ++L LG G+ GVV K+ H+ + + MA K LI+ A K + R
Sbjct: 101 DRIHEFERDHLQELELLGNGSFGVVRKMLHRPSNVEMAVKQISLINNGPDDAFNKSMQRF 160
Query: 136 --ELKVLHEC-NFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAG-----RIPESI 187
E++ N IV +YG +++G +CME MD SLD + A IPE I
Sbjct: 161 RLEVEATKAASNCDEIVRYYGITFNEGVAWMCMELMDL-SLDKLYMIAHDIQKVEIPEQI 219
Query: 188 LGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSF-V 246
LG + A ++ L +L+ H I+HRD+KPSNIL++ +G +K+CDFG+ G L +S+A S V
Sbjct: 220 LGAVAVATIRALEHLKTTHHIIHRDIKPSNILLDRHGCVKLCDFGICGYLQNSVAQSVDV 279
Query: 247 GTRSYMSPERL--QGTHYSVQSDIWSLGLSLVEMAIGMYP 284
G R YM+PERL G Y ++S++WSLG+++VE+A G YP
Sbjct: 280 GCRPYMAPERLAPNGDGYDIKSEVWSLGITMVEVANGKYP 319
>UniRef50_O94804 Cluster: Serine/threonine-protein kinase 10; n=36;
Euteleostomi|Rep: Serine/threonine-protein kinase 10 -
Homo sapiens (Human)
Length = 968
Score = 147 bits (355), Expect = 7e-34
Identities = 94/295 (31%), Positives = 160/295 (54%), Gaps = 37/295 (12%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+E +GELG G G V K ++K TG + A K+I + + ++ I+ E+++L C+ +IV
Sbjct: 36 WEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIV-EIEILATCDHPYIV 94
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKHAI 208
GA+Y DG++ I +E+ GG++D I+ + R + E + + +L+ L++L K I
Sbjct: 95 KLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKR-I 153
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSP-----ERLQGTH 261
+HRD+K N+L+ G+I++ DFGVS + + ++ +SF+GT +M+P E ++ T
Sbjct: 154 IHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTP 213
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
Y ++DIWSLG++L+EMA I PP + PM + L
Sbjct: 214 YDYKADIWSLGITLIEMA----QIEPPH---------------------HELNPMRV--L 246
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEK 376
L ++PP L +S EF+DF+ L KNP+ R L+ H ++ + K
Sbjct: 247 LKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSITSNK 301
>UniRef50_A7P1R5 Cluster: Chromosome chr19 scaffold_4, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr19 scaffold_4, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 706
Score = 144 bits (350), Expect = 3e-33
Identities = 102/300 (34%), Positives = 157/300 (52%), Gaps = 33/300 (11%)
Query: 76 LCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR 135
+ + I + + F L +G+G+ G V K K +A K+I LE + I +
Sbjct: 1 MAEAAAIMDATGSRFSSLELIGRGSFGDVYKGFDKELNKDVAIKVIDLEEAEDEIEDIQK 60
Query: 136 ELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAV 195
E+ VL +C +I +YG++ ++ I MEYM GGS+ +++ + E + I +
Sbjct: 61 EISVLSQCRSPYITEYYGSYLHQTKLWIIMEYMAGGSVADLIQSGQPLDEMSIACILRDL 120
Query: 196 LKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMS 253
L + YL ++ I HRD+K +NIL+ NG++K+ DFGVS QL +++ +FVGT +M+
Sbjct: 121 LHAIEYLHNEGKI-HRDIKAANILLTENGDVKVADFGVSAQLTRTISRRKTFVGTPFWMA 179
Query: 254 PERLQGTH-YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNS 312
PE +Q + Y+ ++DIWSLG++ +EMA G PP LA +
Sbjct: 180 PEVIQNSEGYNEKADIWSLGITAIEMAKG----EPP----LADL---------------- 215
Query: 313 PRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
PM + L I E PP+L FS K+FV CLKK P ER K L+ H +IR A
Sbjct: 216 -HPMRV---LFIIPRENPPQLDEH-FSRPMKEFVSLCLKKVPAERPSAKELLKHRFIRNA 270
>UniRef50_Q55GC2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1142
Score = 144 bits (350), Expect = 3e-33
Identities = 97/295 (32%), Positives = 156/295 (52%), Gaps = 37/295 (12%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
FE + E+ +G+ G V K +H TG IMA K+I L+ + ++ E+ +L+ CN +IV
Sbjct: 20 FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFEDLVV-EIDILNRCNHNNIV 78
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIP--ESILGTITSAVLKGLSYLRDKHA 207
+YG++ E+ I ME GGS+ I ++ IP ES + + LKGL YL +
Sbjct: 79 KYYGSWVKGDELFIAMECCGGGSITEIYQELN-IPLNESQIAYVCRETLKGLEYLHHTNV 137
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQL-IDSMANSFVGTRSYMSPE----RLQGTHY 262
I HRD+K +NIL+ +G++K+ DFGVSG L S N+F+GT +M+PE R Y
Sbjct: 138 I-HRDLKGANILLTESGDVKLADFGVSGLLDKSSKRNTFIGTPYWMAPEVIENRSNPVPY 196
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322
++DIWSLG++L+E+A P+ +E H PM + +
Sbjct: 197 DTKADIWSLGITLIELAEAEPPL---------------SEIH----------PMKVLFQI 231
Query: 323 DYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKV 377
Y +PP +S +F +F+ CL+K+P++R L+ H ++ + + V
Sbjct: 232 PY--RDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPFVTNTKEKAV 284
>UniRef50_Q0UBD3 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 708
Score = 143 bits (346), Expect = 8e-33
Identities = 98/287 (34%), Positives = 151/287 (52%), Gaps = 32/287 (11%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
++++ + ELG G+ G V K + TG I+A K I LE I E+ +L C+ +
Sbjct: 3 ENYQVMEELGSGSFGKVYKAVDRRTGEIVAIKHIDLEDSSEELADIQAEISLLSTCHSPY 62
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
I + +F ++ I ME++ GGS +L G I E+ + + +L GL YL
Sbjct: 63 ITEYKTSFVKGVKLWIVMEFLGGGSAADML-APGPIAEAHIAIMCRELLLGLDYLHSTGK 121
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQL--IDSMANSFVGTRSYMSPERLQGTHYSVQ 265
I HRD+K +N+L+ G +K+ DFGV+ QL I S +FVGT +M+PE +Q Y +
Sbjct: 122 I-HRDIKAANVLLTDQGRVKLADFGVAAQLTNIKSQRMTFVGTPFWMAPEVIQEAGYDFR 180
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYI 325
+DIWSLG++ +E+A G PP + G + PM ++L I
Sbjct: 181 ADIWSLGITAMELAEG---APP---------YAGSH-------------PM---KVLFTI 212
Query: 326 VNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
P P+L +S +FKDF+ +CL K+PD RA K L+ H +I +A
Sbjct: 213 PKNPAPRLTGDQWSKDFKDFIAQCLIKDPDRRATAKELLKHRFIMRA 259
>UniRef50_Q4Q2Z2 Cluster: Protein kinase, putative; n=6;
Trypanosomatidae|Rep: Protein kinase, putative -
Leishmania major
Length = 385
Score = 142 bits (345), Expect = 1e-32
Identities = 92/304 (30%), Positives = 157/304 (51%), Gaps = 39/304 (12%)
Query: 84 ELSDDDFEKLGELGQGN-GGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE 142
+L+ ++ +++ +LGQG G V M V + + + I + + ++ + EL+ +
Sbjct: 52 DLNFENLKRVRQLGQGTQGNVSMYVTADKSVFAVKKITIPVTLDTRTRQTVAAELRNIFS 111
Query: 143 CNF-AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201
+ V Y AFY + + + MEYMD G++D ++ + +IP ++ G I S +L L+
Sbjct: 112 AQSNEYTVNLYNAFYRNRALRLVMEYMDWGNIDELIAEKVKIPPTVCGYIASQMLHALAV 171
Query: 202 LRDKHAIM------------HRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTR 249
L K I+ HRD+KP+N+L+++ G +K+ DFG++ NSFVGT
Sbjct: 172 LHTKSNIVTEPNQHKSLRQIHRDIKPANVLLSTTGCVKLADFGIATSAETIGVNSFVGTA 231
Query: 250 SYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQA 309
+YMSPER+QG YS SDIWS+G+ + +M +G YP S G+
Sbjct: 232 TYMSPERIQGRRYSTPSDIWSVGVVVAQMLLGHYPF------------------SSVGKG 273
Query: 310 PNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
MA+ ++ + E P + S E +DF+D CL+++PD+R+ L+ WI
Sbjct: 274 -----FMALLREINSV--EKYPLMEETGCSQEAQDFIDSCLRQDPDDRSSAFELLESPWI 326
Query: 370 RKAE 373
+ E
Sbjct: 327 KYCE 330
>UniRef50_O61125 Cluster: Kinase responsive to stress 1-like kinase;
n=2; Dictyostelium discoideum|Rep: Kinase responsive to
stress 1-like kinase - Dictyostelium discoideum (Slime
mold)
Length = 461
Score = 142 bits (345), Expect = 1e-32
Identities = 98/304 (32%), Positives = 159/304 (52%), Gaps = 35/304 (11%)
Query: 79 KEKIGELSDDDFEKLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIREL 137
KE + + F + E LG+G+ G V K + STG+++A K + ++ + + +E+
Sbjct: 8 KETMSRKDPEKFFTIVEKLGEGSYGSVYKAINISTGIVVAIKKVSVDND---LEDMEKEI 64
Query: 138 KVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVL 196
+ +C +IV +Y +F + E+ I ME+ GS+ +K + + E + ++ VL
Sbjct: 65 SFMKQCKSPYIVTYYASFRKENEVWIVMEHCGAGSVCDAMKITDKTLSEDQIAVVSRDVL 124
Query: 197 KGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSP 254
+GL+YL I HRD+K NIL+N GE K+ DFGVSGQL D+MA + +GT +M+P
Sbjct: 125 QGLAYLHSVRKI-HRDIKAGNILMNHKGESKLADFGVSGQLSDTMAKRQTVIGTPFWMAP 183
Query: 255 ERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPR 314
E +Q Y ++DIWS G++ +EMA P+ + + IF PN R
Sbjct: 184 EVIQEIGYDYKADIWSYGITCIEMAESKPPL--FNVHPMRVIF----------MIPNPSR 231
Query: 315 PMAIFELLDYIVNEPPPKLPS-GIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
PPPKL +S EF DF+ +CL + P+ R + L+ H +I KA+
Sbjct: 232 --------------PPPKLTEPEKWSPEFNDFLAKCLTRKPELRPSAEELLKHPFITKAK 277
Query: 374 AEKV 377
+ +
Sbjct: 278 SHSL 281
>UniRef50_Q9M8J5 Cluster: Putative MAP kinase; n=1; Arabidopsis
thaliana|Rep: Putative MAP kinase - Arabidopsis thaliana
(Mouse-ear cress)
Length = 293
Score = 142 bits (343), Expect = 2e-32
Identities = 86/224 (38%), Positives = 130/224 (58%), Gaps = 21/224 (9%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148
+ +++ LG GNGG V KV+ K+T I A K +VK +RE+++L N ++
Sbjct: 52 NLDRISVLGSGNGGTVFKVKDKTTSEIYALK----KVKENWDSTSLREIEILRMVNSPYV 107
Query: 149 VGFYGAFYS-DGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
+ F + GE+SI M+YMD GSL+ + + E L ++ VL+G +YL + H
Sbjct: 108 AKCHDIFQNPSGEVSILMDYMDLGSLESLRG----VTEKQLALMSRQVLEGKNYLHE-HK 162
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPERLQGTHYSV- 264
I+HRD+KP+N+L +S E+KI DFGVS ++ S+ NSFVGT +YMSPERL V
Sbjct: 163 IVHRDIKPANLLRSSKEEVKIADFGVSKIVVRSLNKCNSFVGTFAYMSPERLDSEADGVT 222
Query: 265 --------QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQ 300
DIWS GL+++E+ +G YP+ P A + A+ G+
Sbjct: 223 EEDKSNVYAGDIWSFGLTMLEILVGYYPMLPDQAAIVCAVCFGE 266
>UniRef50_Q55FS2 Cluster: Calpain-like cysteine protease; n=1;
Dictyostelium discoideum AX4|Rep: Calpain-like cysteine
protease - Dictyostelium discoideum AX4
Length = 1105
Score = 142 bits (343), Expect = 2e-32
Identities = 93/286 (32%), Positives = 150/286 (52%), Gaps = 34/286 (11%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148
+F+ + LG+G+ G V K +K TG I+A KL+ + ++I++E+ ++ +C ++
Sbjct: 22 EFDLIECLGRGSFGSVYKATYKKTGNIVAVKLVPINED---FQEILKEINIMKQCKSKYV 78
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRI-PESILGTITSAVLKGLSYLRDKHA 207
V +YG ++ D I MEY GS+ ++ R+ E + + + LKGL YL +++
Sbjct: 79 VQYYGNYFKDETCWIIMEYCAFGSVSDMMNITNRVLNEEQIALVCYSTLKGLYYLH-RNS 137
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTHYSVQ 265
+HRD+KP NILV+ GE K+ DFGVSGQL + N+ +GT +++PE +Q Y +
Sbjct: 138 KIHRDIKPGNILVSEEGECKLADFGVSGQLSERTRKRNTVIGTPFFLAPEVIQEVGYDNK 197
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYI 325
+DIW+LG+S +EMA +P P D + +F P S P
Sbjct: 198 ADIWALGISAIEMA-EFHP-PYHDLHPMRVLF----------MIPTSTSP---------T 236
Query: 326 VNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
+ EP +S EF DF+ CL K +R K L+ H + K
Sbjct: 237 LKEPHK------WSPEFSDFIALCLAKEQSQRPSAKDLLKHSFFEK 276
>UniRef50_Q0CAV5 Cluster: Serine/threonine-protein kinase 24; n=7;
Fungi/Metazoa group|Rep: Serine/threonine-protein kinase
24 - Aspergillus terreus (strain NIH 2624)
Length = 610
Score = 141 bits (342), Expect = 3e-32
Identities = 94/258 (36%), Positives = 139/258 (53%), Gaps = 34/258 (13%)
Query: 118 RKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGS-LDLI 176
R I LE ++I +E+ VL C ++ + +F ++ I MEY+ GGS LDL+
Sbjct: 44 RNGIDLESSEDDIQEIQQEISVLATCASQYVTQYKASFLRGHKLWIVMEYLGGGSCLDLL 103
Query: 177 LKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQ 236
K G E+ + I +L+GL YL + I HRD+K +N+L++ G++K+ DFGV+ Q
Sbjct: 104 --KPGVFNEAHVAIICHQLLQGLDYLHCEGKI-HRDIKAANVLLSHTGKVKLADFGVAAQ 160
Query: 237 L--IDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLA 294
L I S N+FVGT +M+PE +Q Y ++DIWSLG++ +EM G PP A T
Sbjct: 161 LTNIKSQRNTFVGTPFWMAPEVIQQAGYDYKADIWSLGITAIEMING----EPPHAST-- 214
Query: 295 AIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNP 354
PM + L I EP P+L +S+ FKDF+ +CL K+P
Sbjct: 215 -------------------HPMKVLFL---IPKEPAPRLEGDQYSNTFKDFIAQCLTKDP 252
Query: 355 DERADLKTLMNHEWIRKA 372
D R K L+ H++IR A
Sbjct: 253 DRRPSAKELLRHKFIRNA 270
>UniRef50_Q9LQA1 Cluster: F4N2.17; n=8; Magnoliophyta|Rep: F4N2.17 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1120
Score = 140 bits (340), Expect = 5e-32
Identities = 95/288 (32%), Positives = 151/288 (52%), Gaps = 33/288 (11%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+E L ELG+G+ G V K R T I+A K+I L ++I E+++L +CN ++V
Sbjct: 249 YEFLNELGKGSYGSVYKARDLKTSEIVAVKVISLTEGEEGYEEIRGEIEMLQQCNHPNVV 308
Query: 150 GFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+ G++ + + I MEY GGS+ DL+ + E + I LKGL+YL + +
Sbjct: 309 RYLGSYQGEDYLWIVMEYCGGGSVADLMNVTEEALEEYQIAYICREALKGLAYLHSIYKV 368
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQS 266
HRD+K NIL+ GE+K+ DFGV+ QL +M+ N+F+GT +M+PE +Q Y +
Sbjct: 369 -HRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVIQENRYDGKV 427
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
D+W+LG+S +EMA G +PP +S PM + ++
Sbjct: 428 DVWALGVSAIEMAEG---LPP----------------------RSSVHPMRVLFMISI-- 460
Query: 327 NEPPPKL-PSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
EP P L +S F DFV +CL K P R ++ H+++ + +
Sbjct: 461 -EPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTAAEMLKHKFVERCK 507
>UniRef50_A0E889 Cluster: Chromosome undetermined scaffold_82, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_82,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 506
Score = 140 bits (340), Expect = 5e-32
Identities = 101/294 (34%), Positives = 154/294 (52%), Gaps = 36/294 (12%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVL-HECNF 145
++ FE +GQG V K RHK+ G I+A K++ + + +I+E+++L EC
Sbjct: 8 EEQFELNELIGQGAYAKVYKGRHKN-GQIVAIKIVPSNGEI---QSLIKEIQILKQECQH 63
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGS-LDLILKKAGRIPESILGTITSAVLKGLSYLRD 204
AHIV +YG+FY DG + + MEY GGS +DL+ + ES + I VL G+ YL
Sbjct: 64 AHIVQYYGSFYKDGNLWLVMEYCVGGSIIDLLKITQKTLTESEIAAILYHVLLGIEYLHA 123
Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTHY 262
I HRD+K NIL++ G IKI DFGV+ QLI + A+ + +GT YMSPE + Y
Sbjct: 124 NKKI-HRDIKAGNILLDEKGTIKIADFGVAAQLIYTNADKGTVIGTPVYMSPEVISKNRY 182
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322
+ +DIWSLG++ +E+A G P + A+F +N +P Q +P
Sbjct: 183 NHLTDIWSLGVTAIELAEGKPPY--SHIHPVRAMFAIKN---NPPQGLTNPEK------- 230
Query: 323 DYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEK 376
+S EF DFV CL+ ER + L+ +I++ + ++
Sbjct: 231 ---------------WSKEFNDFVKSCLRVQVSERPSAQQLLQSPFIKQGKQDQ 269
>UniRef50_Q22AD4 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1193
Score = 140 bits (338), Expect = 8e-32
Identities = 96/313 (30%), Positives = 162/313 (51%), Gaps = 35/313 (11%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146
++ FE L LG+G+ G V K HK TG ++A K++ E A++K E+++L EC
Sbjct: 18 EEIFEILDLLGEGSYGQVYKALHKQTGELVAVKMVPNEGDSALEK----EIRMLKECQSE 73
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
++V +Y ++Y D + + MEY GS+ DL+ ++ E + +I + LKGL YL
Sbjct: 74 YVVKYYASYYKDQHLWLIMEYCAAGSIIDLVKITRIQLNEQQIASILQSTLKGLQYLHS- 132
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLI--DSMANSFVGTRSYMSPERLQGTHYS 263
+ I+HRD+K NIL++ G K+ DFGVS Q I + A S +GT +M+PE + Y
Sbjct: 133 NKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQAKAESKIGTPCWMAPEVIMHLKYD 192
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLD 323
++DIWSLG++ +E+A G PP + ++ + + P N
Sbjct: 193 SKADIWSLGITAIELAEG----EPPYSDVKPSMVMAKIQQKPPQGLKN------------ 236
Query: 324 YIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGWV 383
P S F+D FV +CL+++P +R + L+ H +I++ K ++ V
Sbjct: 237 -------PSQWSQQFND----FVKQCLQQDPQKRPTAEQLLQHPFIKENSRPKAILSELV 285
Query: 384 CKTMDLMPSTPNS 396
++D + N+
Sbjct: 286 SNSIDAIERYRNN 298
>UniRef50_Q7QR27 Cluster: GLP_576_6939_8012; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_576_6939_8012 - Giardia lamblia ATCC
50803
Length = 357
Score = 139 bits (337), Expect = 1e-31
Identities = 81/214 (37%), Positives = 123/214 (57%), Gaps = 10/214 (4%)
Query: 80 EKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELK- 138
E I + + D E + LG G G V V+ K+TG + A K I + + +K I RE+K
Sbjct: 63 EHILNVQESDLEVVKPLGAGAFGTVNLVKVKTTGQLCAMKEIRISDEEQTQKNIYREIKA 122
Query: 139 -VLHECNFAHIVGFYGAFYSDGEI-SICMEYMD-GGSLDLILK-KAGRIPESILGTITSA 194
+ CN ++V Y + G I I +E+ G S D++ K K G++ E+ L
Sbjct: 123 SISLSCN-PYMVKTYNIYSHPGSILHILLEFCKYGSSQDMLKKLKTGKLTENALAVFIID 181
Query: 195 VLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLI----DSMANSFVGTRS 250
L+GL+YL D I+HRD+K +NIL++ +G K+ DFGV+ ++ ++ +FVG+ S
Sbjct: 182 TLRGLAYLHDNCKIIHRDIKSANILIDEHGYCKLADFGVASSVLPNDDEAAMKTFVGSLS 241
Query: 251 YMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284
YMSPER+Q YS SD+WS+GL+ VE+ G YP
Sbjct: 242 YMSPERIQNQPYSYVSDVWSMGLTYVELLTGSYP 275
>UniRef50_A5BPZ0 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 715
Score = 139 bits (336), Expect = 1e-31
Identities = 79/284 (27%), Positives = 143/284 (50%), Gaps = 11/284 (3%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLE-VKPAIKKQIIRELKVLHECNFAHIVGFYGA 154
+G G+ VV + RH+ +G+++A K I E + P +K + +E+++L N +I+ A
Sbjct: 21 IGSGSYAVVWESRHRQSGMVVAIKEIDKEHLNPKVKDNLFKEIEILRTINHPNIIRLLQA 80
Query: 155 FYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVK 214
+ I + +EY DGG L + + GR+PE++ + GL L +K ++HRD+K
Sbjct: 81 IETSDRIFLVLEYCDGGDLAAYIHRRGRVPEAVARHFMRQLAAGLQVLHEKR-LIHRDLK 139
Query: 215 PSNILVNSNGE-----IKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIW 269
P N+L+++N +KI DFG + L +A++ G+ YM+PE +Q Y ++D+W
Sbjct: 140 PQNLLLSTNEATTAPLLKIGDFGFARDLTQGLADTQCGSPLYMAPEIIQNQKYDAKADLW 199
Query: 270 SLGLSLVEMAIGMYPIP-PPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNE 328
S+G L ++ G P + L + + + N + + + L I++
Sbjct: 200 SVGAILFQLVTGRPPFDGSTQFQVLITVVVNSLREIISFNSYNHSQKLQVMLLFHNILSA 259
Query: 329 PPPKLPSGIFSDEFKDFVDRC---LKKNPDERADLKTLMNHEWI 369
+ P G + D VD C L++NP ER NH+++
Sbjct: 260 SELRFPQGALQELHPDCVDLCRRLLRQNPVERLTFNEFFNHKFL 303
>UniRef50_A7P2E2 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=6; Magnoliophyta|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 784
Score = 138 bits (335), Expect = 2e-31
Identities = 96/288 (33%), Positives = 150/288 (52%), Gaps = 33/288 (11%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+E L ELG+G+ G V K R T ++A K+I L ++I E+++L +C+ ++V
Sbjct: 213 YELLNELGKGSYGAVYKARDIRTSELVAIKVISLCEGEEGYEEIRGEIEMLQQCSHPNVV 272
Query: 150 GFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+ G++ + + I MEY GGS+ DL+ + E + I LKGLSYL +
Sbjct: 273 RYLGSYQGEEYLWIVMEYCGGGSVADLMNTTEEPLDEYQIAYICREALKGLSYLHSIFKV 332
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQS 266
HRD+K NIL+ GE+K+ DFGV+ QL +M+ N+F+GT +M+PE +Q + Y +
Sbjct: 333 -HRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVIQESRYDGKV 391
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
D+W+LG+S +EMA G +PP A PM + ++
Sbjct: 392 DVWALGVSAIEMAEG---LPPRSA----------------------VHPMRVLFMISI-- 424
Query: 327 NEPPPKL-PSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
EP P L +S F DFV +CL K P R ++ H++I K +
Sbjct: 425 -EPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTASEMLKHKFIEKCK 471
>UniRef50_Q54B33 Cluster: Putative uncharacterized protein pakE;
n=1; Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein pakE - Dictyostelium discoideum
AX4
Length = 926
Score = 138 bits (335), Expect = 2e-31
Identities = 100/300 (33%), Positives = 159/300 (53%), Gaps = 36/300 (12%)
Query: 83 GELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE 142
G +D FE +LGQG G V KV H+ T +A K+ L + P K I +E+ +L +
Sbjct: 643 GTSVEDTFEFKEKLGQGGYGAVFKVLHRETNFPLAIKV--LSITPTRIKDIEKEIDLLKK 700
Query: 143 CNFAHIVGFYGAFYSD-GEISICMEYMDGGSLDLILKKA-GRIPESILGTITSAVLKGLS 200
C +++ +YG+ S E+ I M++ GS++ ++K + E + +T VL GL
Sbjct: 701 CRCPNVLSYYGSISSKLTELWILMDHCAVGSINDMMKICCDTLDEEQIAVVTLNVLNGLG 760
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQ 258
YL K I+H DVK +NIL+ + +IKI DFGVS QL AN ++G+ YM+PE +
Sbjct: 761 YLHSK-GIVHLDVKAANILLTEDKQIKIADFGVSQQLQTEYGQANVYIGSPLYMAPEVIL 819
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
Y+ ++DIWSLG++L+E+A G PP+ G + + PN P
Sbjct: 820 KAPYNSKADIWSLGITLIELAEGR----PPNR--------GLRSMNQLVEIPNMP----- 862
Query: 319 FELLDYIVNEPPPKLPS-GIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKV 377
PPKL + +S F +F+ CL K+P +R + L++H++I+ A+ +V
Sbjct: 863 -----------PPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFIKNAKTTEV 911
>UniRef50_A0EER6 Cluster: Chromosome undetermined scaffold_92, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_92,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 527
Score = 138 bits (335), Expect = 2e-31
Identities = 97/279 (34%), Positives = 149/279 (53%), Gaps = 34/279 (12%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
+G+G+ G V K G +A K++ + K RE+++L +C +IV ++G++
Sbjct: 18 IGEGSYGQVYKGIQLDNGKAVAIKIVPSSGEIESLK---REIQILRDCRCDNIVKYFGSY 74
Query: 156 YSDGEISICMEYMDGGS-LDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVK 214
+S+G++ + MEY GGS L+LI +PE I+ TI +KG+ Y+ H +HRDVK
Sbjct: 75 HSNGQLWLIMEYCSGGSVLELIKALQYPLPEEIIATILYQTVKGIDYMHS-HKKIHRDVK 133
Query: 215 PSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQSDIWSLG 272
NIL++ G IK+ DFGVS QL+ +MA ++ +G+ +MSPE L + YS ++DIWSLG
Sbjct: 134 CGNILIDHLGNIKLADFGVSTQLVHTMADTDTVIGSPFWMSPEILLKSRYSKKTDIWSLG 193
Query: 273 LSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPK 332
++ +EMA G P + A+F +N PNS L D
Sbjct: 194 ITAIEMAEGEPPY--AHIHPIRAMFAIKN------NPPNS--------LTD--------- 228
Query: 333 LPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
+S EF FV RCL +P ER K L+ + +K
Sbjct: 229 --QSKWSREFNQFVKRCLTLDPKERPSTKELLQDPFFQK 265
>UniRef50_Q9H2G2 Cluster: STE20-like serine/threonine-protein
kinase; n=32; Deuterostomia|Rep: STE20-like
serine/threonine-protein kinase - Homo sapiens (Human)
Length = 1235
Score = 138 bits (335), Expect = 2e-31
Identities = 94/295 (31%), Positives = 157/295 (53%), Gaps = 38/295 (12%)
Query: 84 ELSDDDF-EKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE 142
+L+ +DF E +GELG G G V K ++K T ++ A K+I + + ++ ++ E+ +L
Sbjct: 27 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMV-EIDILAS 85
Query: 143 CNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSY 201
C+ +IV AFY + + I +E+ GG++D ++ + R + ES + + L L+Y
Sbjct: 86 CDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNY 145
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPERL-- 257
L D + I+HRD+K NIL +G+IK+ DFGVS + ++ +SF+GT +M+PE +
Sbjct: 146 LHD-NKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMC 204
Query: 258 ---QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPR 314
+ Y ++D+WSLG++L+EMA I PP +
Sbjct: 205 ETSKDRPYDYKADVWSLGITLIEMA----EIEPPH---------------------HELN 239
Query: 315 PMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
PM + LL +EPP +S FKDF+ +CL+KN D R L+ H ++
Sbjct: 240 PMRV--LLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFV 292
>UniRef50_O55092 Cluster: STE20-like serine/threonine-protein
kinase; n=3; Euteleostomi|Rep: STE20-like
serine/threonine-protein kinase - Cavia porcellus
(Guinea pig)
Length = 1231
Score = 138 bits (335), Expect = 2e-31
Identities = 93/295 (31%), Positives = 158/295 (53%), Gaps = 38/295 (12%)
Query: 84 ELSDDDF-EKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE 142
+L+ ++F E +GELG G G V K ++K T ++ A K+I + + ++ ++ E+ +L
Sbjct: 27 DLNPEEFWETIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMV-EIDILAS 85
Query: 143 CNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSY 201
C+ +IV AFY + + I +E+ GG++D ++ + R + ES + + L+ L+Y
Sbjct: 86 CDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNY 145
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPERL-- 257
L D + I+HRD+K NIL +G+IK+ DFGVS + ++ +SF+GT +M+PE +
Sbjct: 146 LHD-NKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMC 204
Query: 258 ---QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPR 314
+ Y ++D+WSLG++L+EMA I PP +
Sbjct: 205 ETSKDRPYDYKADVWSLGITLIEMA----EIEPPH---------------------HELN 239
Query: 315 PMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
PM + LL +EPP +S FKDF+ +CL+KN D R L+ H ++
Sbjct: 240 PMRV--LLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFV 292
>UniRef50_Q22AY1 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1203
Score = 138 bits (333), Expect = 3e-31
Identities = 101/298 (33%), Positives = 155/298 (52%), Gaps = 40/298 (13%)
Query: 92 KLG-ELGQGNGGVVMKVRHKSTGLIMARKLIH-LEVKPAIKKQIIRELKVLHECNFAHIV 149
K+G +LGQG G V K H TG ++A KL+ + +K K I +E+ +L + +IV
Sbjct: 17 KVGVKLGQGASGTVYKGEHIETGQVVAIKLVSTVNIKKENIKSIKKEMHLLKKLKHENIV 76
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+ ++ +I +EY++ GSL I+KK G ES++ VL+GL YL + I+
Sbjct: 77 TYIDFIQTENHYAIILEYIESGSLYGIIKKFGPFQESLVIIFIKQVLRGLEYLH-RQGIV 135
Query: 210 HRDVKPSNILV---NSNGEIKICDFGVSGQLIDSMANS--FVGTRSYMSPERL--QGTHY 262
HRD+K +NIL N +G IK+ DFGV+ L D +S VGT +M+PE + H
Sbjct: 136 HRDIKGANILTTKNNKSGVIKLTDFGVATHLADDDKSSTQCVGTPYWMAPEVIIDSDGHI 195
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322
S DIWSLG +++E+ G PP + N H A+F +
Sbjct: 196 STSCDIWSLGCTIIELLTGN---PP---------YSYGNPHH------------ALFRM- 230
Query: 323 DYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR-KAEAEKVDI 379
V++ P LP + + + DF+ +C K P +R D K+L+NHEW++ E E + I
Sbjct: 231 ---VSDQHPPLPKDV-TPQCLDFLMQCFNKEPSQRMDAKSLLNHEWLKINIETEVLQI 284
>UniRef50_UPI0000F53448 Cluster: STE20-LIKE SERINE-THREONINE KINASE;
n=2; Eutheria|Rep: STE20-LIKE SERINE-THREONINE KINASE -
Homo sapiens
Length = 326
Score = 137 bits (331), Expect = 6e-31
Identities = 94/296 (31%), Positives = 155/296 (52%), Gaps = 39/296 (13%)
Query: 84 ELSDDDF-EKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE 142
+L+ +DF E +GELG G G V K ++K T ++ A K+I + + ++ ++ E+ +L
Sbjct: 32 DLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMV-EIDILAS 90
Query: 143 CNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSY 201
C+ +IV AFY + + I +E+ GG++D ++ + R + ES + + L L+Y
Sbjct: 91 CDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNY 150
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSG---QLIDSMANSFVGTRSYMSPERL- 257
L D + I+HRD+K NIL +G+IK+ DFGVS + +SF+GT +M+PE +
Sbjct: 151 LHD-NKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTXIQRRDSFIGTPYWMAPEVVM 209
Query: 258 ----QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
+ Y ++D+WSLG++L+EMA I PP +
Sbjct: 210 CETSKDRPYDYKADVWSLGITLIEMA----EIEPPH---------------------HEL 244
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
PM + LL +EPP +S FKDF+ +CL+KN D R L+ H ++
Sbjct: 245 NPMRV--LLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFV 298
>UniRef50_Q54XJ4 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1495
Score = 136 bits (330), Expect = 7e-31
Identities = 89/293 (30%), Positives = 152/293 (51%), Gaps = 38/293 (12%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQ----IIRELKVLHECN 144
D+ + +G+G GVV K HK+ G A K I + K ++ + ++ E+ +L +
Sbjct: 21 DYLLIDIIGKGGFGVVYKGLHKTKGYFSAIKKIKIMKKKKLQSESQISLMAEINLLKVLS 80
Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRD 204
+IV +Y S I ME+++ GSL+ I+K+ G +PES++ + VL GL YL
Sbjct: 81 HHNIVRYYEHIPSSSHSYIVMEFIENGSLEKIIKRHGLLPESLVTVYIAQVLNGLEYLH- 139
Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA----NSFVGTRSYMSPERLQGT 260
+ ++HRD+K +N+L++++G IK+ DFGV+ ++ D + ++F GT +M+PE +Q
Sbjct: 140 RQGVIHRDIKAANLLISTDGSIKLADFGVATKVSDLSSDNPDDTFAGTPYWMAPEVIQMQ 199
Query: 261 HYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFE 320
S D+WSLG +++E+ G P AA++ EDH P
Sbjct: 200 GISTACDVWSLGCTIIELLTGTPPY--FGLAPAAALYKIVQEDHPP-------------- 243
Query: 321 LLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
+P GI S KDF+ C KK+ + R+ K L++H W++ +
Sbjct: 244 ------------IPPGI-SAALKDFLLNCFKKDENIRSSAKQLLHHPWVKSVQ 283
>UniRef50_A0C8K1 Cluster: Chromosome undetermined scaffold_158,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_158,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 873
Score = 136 bits (330), Expect = 7e-31
Identities = 96/286 (33%), Positives = 152/286 (53%), Gaps = 35/286 (12%)
Query: 92 KLGEL-GQGNGGVVMKVRHKSTGLIMARKLI-HLEVKPAIKKQIIRELKVLHECNFAHIV 149
+LG+L G+G+ G V K + G ++A K + +K K + +E+ +L + +IV
Sbjct: 15 QLGDLLGRGSIGTVYKGLNLELGTLVAIKQVSRATLKEDQYKALQQEIYLLKKLKHENIV 74
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+ +D ++I +EY++ GSL ILKK G PES++ VLKGL YL + I+
Sbjct: 75 KYIDCIETDQFLNIILEYIESGSLASILKKFGSFPESLVAIYVKQVLKGLEYLH-QQGIV 133
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQ-GTHYSVQS 266
HRD+K +NIL +G +K+ DFGV+ L + + +N+ VGT +M+PE ++ H S
Sbjct: 134 HRDIKGANILTPKDGTVKLADFGVATTLSEDTTQSNNIVGTPYWMAPEVIEMSGHLSTSC 193
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
DIWSLG +++E+ G P D AA+F +
Sbjct: 194 DIWSLGCTVIELLTGNPPY--FDRLQYAAMF-------------------------QIVQ 226
Query: 327 NEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
+ PP LP GI S+E +DF+ +C +K+P R D T++ H WI K+
Sbjct: 227 RDCPP-LPEGI-SNECRDFLIQCFQKDPTLRDDATTMLKHPWITKS 270
>UniRef50_Q6BP91 Cluster: Debaryomyces hansenii chromosome E of
strain CBS767 of Debaryomyces hansenii; n=1;
Debaryomyces hansenii|Rep: Debaryomyces hansenii
chromosome E of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 463
Score = 136 bits (330), Expect = 7e-31
Identities = 94/280 (33%), Positives = 151/280 (53%), Gaps = 35/280 (12%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
+G+GN G V K S ++A K+I+L+ +I+E++ L + +I ++ F
Sbjct: 12 IGKGNFGDVYKATDISNNTLVAVKVINLDESDEDIAVLIQEIQFLSKLRSPYITKYFETF 71
Query: 156 YSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKP 215
+D + I MEY GGS +LK ++ E I VL+GL+YL +++ + HRD+K
Sbjct: 72 INDMSMWIVMEYCGGGSCADLLKCYRKLNEETTAFIIRDVLRGLTYLHEENKV-HRDIKL 130
Query: 216 SNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPE---RLQGTHYSVQSDIWS 270
+NIL+ S GEIK+ DFGVSG++ + N+FVGT +M+PE RL+ T Y+ ++DIWS
Sbjct: 131 ANILLTSYGEIKLADFGVSGEITMTQLKRNTFVGTPFWMAPEVITRLK-TGYNEKADIWS 189
Query: 271 LGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPP 330
G++ +E+ G P+ D PM ++L I + P
Sbjct: 190 TGITTIELVTGSPPLSQYD-------------------------PM---KILFEIPKKRP 221
Query: 331 PKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370
P L FS+ KDFV CL K+P +R TL++H++++
Sbjct: 222 PLLTGVDFSENIKDFVRYCLIKDPKKRPSSSTLLHHKFLK 261
>UniRef50_Q7SY52 Cluster: Zgc:63495; n=10; Euteleostomi|Rep:
Zgc:63495 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 974
Score = 136 bits (329), Expect = 1e-30
Identities = 91/298 (30%), Positives = 156/298 (52%), Gaps = 37/298 (12%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146
+D +E +GELG G G V K ++K TG++ A K+I + + ++ ++ E+ +L CN
Sbjct: 34 NDMWEIIGELGDGAFGKVYKAQNKETGVLAAAKVIETKSEEELEDYMV-EIDILASCNHQ 92
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDK 205
+IV AF+ D ++SI +E+ GG++D I+ + R + E + I +L+ L YL
Sbjct: 93 YIVKLLDAFFFDNKLSIMIEFCPGGAVDAIMLELDRGLQEPQIRVICKQMLEALQYLHSM 152
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSP-----ERLQ 258
I+HRD+K NIL+ +G+IK+ DFGVS + ++ +SF+GT +M+P E ++
Sbjct: 153 -KIIHRDLKAGNILLTLDGDIKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETMK 211
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
Y ++DIWSLG++L+E+A I PP + PM +
Sbjct: 212 DAPYDYKADIWSLGITLIELA----QIEPPH---------------------HELNPMRV 246
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEK 376
LL +EPP +S +F DF+ + L ++P+ R L+ H ++ +
Sbjct: 247 --LLKIAKSEPPGLDQPSKWSMDFNDFLKKALDRHPETRPTAAQLLEHPFVSSVNTNR 302
>UniRef50_Q551J3 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum AX4
Length = 1167
Score = 136 bits (328), Expect = 1e-30
Identities = 91/282 (32%), Positives = 151/282 (53%), Gaps = 31/282 (10%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQ-IIRELKVLHECNFAHIVGFYGA 154
+G+G G V + G +A K I+L P + Q I+ E+ +L N A+IV +
Sbjct: 24 IGKGGFGTVYQGLDIEDGDFVAIKQINLTKIPKDQLQGIMNEIDLLKNLNHANIVKYIKY 83
Query: 155 FYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVK 214
+ + I +EY++ GSL I+KK G+ PE+++ VL+GL YL ++ ++HRD+K
Sbjct: 84 VKTKDNLYIVLEYVENGSLSGIIKKFGKFPETLVCVYIRQVLEGLVYLHEQ-GVVHRDIK 142
Query: 215 PSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLS 274
+NIL G+IK+ DFGV+ + D+ A + VGT +M+PE ++ + +SDIWS+G +
Sbjct: 143 GANILTTKEGKIKLADFGVATKFDDTSAAAVVGTPYWMAPEIIELNGATTKSDIWSVGCT 202
Query: 275 LVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLP 334
++E+ G P + GQ P A+F IV + P LP
Sbjct: 203 VIELLTGSPPY------------------YDLGQMP------ALFR----IVQDDCPPLP 234
Query: 335 SGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEK 376
GI S KD++ +C +K+P+ R + L+ H+WI+ + +K
Sbjct: 235 EGI-SPPLKDWLMQCFQKDPNLRISAQKLLKHKWIQASIKKK 275
>UniRef50_A2QHV0 Cluster: Contig An04c0070, complete genome; n=4;
Trichocomaceae|Rep: Contig An04c0070, complete genome -
Aspergillus niger
Length = 1336
Score = 136 bits (328), Expect = 1e-30
Identities = 96/293 (32%), Positives = 152/293 (51%), Gaps = 35/293 (11%)
Query: 82 IGELSDDDFEKLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR-ELKV 139
+ EL D +LG+ LG+G G V + + +TG +A K I L P + ++I E+ +
Sbjct: 53 VAELKD---YQLGDCLGKGAFGSVYRALNWNTGETVAVKQIKLVDLPKSELRVIMLEIDL 109
Query: 140 LHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGL 199
L + +IV + G S ++I +EY + GSL I K GR PE+++G S VL GL
Sbjct: 110 LKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHSIAKNFGRFPENLVGLYMSQVLHGL 169
Query: 200 SYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQG 259
YL ++ ++HRD+K +NIL G +K+ DFGV+ + +S VGT +M+PE ++
Sbjct: 170 LYLHEQ-GVIHRDIKGANILTTKEGLVKLADFGVASRTTGLSESSVVGTPYWMAPEVIEL 228
Query: 260 THYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIF 319
+ + SDIWSLG +++E+ G P + + + A+F N+DH P
Sbjct: 229 SGATTASDIWSLGCTVIELLEGKPPY--YNLQPMPALFRIVNDDHPP------------- 273
Query: 320 ELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
LP G S KDF+ +C +K+P+ R + L+ H WI A
Sbjct: 274 -------------LPQGA-SPAVKDFLMQCFQKDPNLRVSARKLLKHPWIVNA 312
>UniRef50_Q22A21 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 280
Score = 135 bits (327), Expect = 2e-30
Identities = 85/256 (33%), Positives = 130/256 (50%), Gaps = 42/256 (16%)
Query: 130 KKQIIRELKVL-HECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESIL 188
+ Q++ + KVL + +++ +GA+Y +G I I +E MD GS+ ++ I L
Sbjct: 10 RHQMLNDFKVLLTQYTHPNLITCFGAYYEEGTIKIILELMDFGSIRNLIDMLKEINYCYL 69
Query: 189 GT------------ITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQ 236
I +LKGL +L + +HRD+KP NIL+N G +K+ DFG+S Q
Sbjct: 70 SKILCNQKYQYHFFILKQLLKGLEFLHKERHQVHRDIKPENILINKRGNVKLTDFGISKQ 129
Query: 237 L--IDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLA 294
L + ++VGT YMSPERL G Y ++SDIWS+GL ++E+A G+YP D K
Sbjct: 130 LEKTQQLCMTYVGTTLYMSPERLIGNQYGLRSDIWSVGLVIIELATGLYPY---DVKN-- 184
Query: 295 AIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLP-SGIFSDEFKDFVDRCLKKN 353
+I + + I+ P LP +G +S DFV +C+ K
Sbjct: 185 ---------------------KSIVQFVSNILQSKEPTLPDNGKYSAALMDFVKKCVAKE 223
Query: 354 PDERADLKTLMNHEWI 369
+R D+ L+ HEWI
Sbjct: 224 QKDRLDISDLLKHEWI 239
>UniRef50_Q4P842 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 724
Score = 135 bits (327), Expect = 2e-30
Identities = 84/225 (37%), Positives = 127/225 (56%), Gaps = 33/225 (14%)
Query: 151 FYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMH 210
++G++ + I MEY GGS ++K GR E + + +LKGL YL + + H
Sbjct: 112 YHGSWLKGTNLWIVMEYCSGGSCSDLMKP-GRFREDYIAIVVRELLKGLEYLHGEGKL-H 169
Query: 211 RDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQSDI 268
RD+K +NIL+++ G++K+ DFGVSGQL +M N+FVGT +MSPE ++ + Y ++DI
Sbjct: 170 RDIKAANILLSATGDVKLADFGVSGQLTATMTKKNTFVGTPYWMSPEVIKQSGYDFKADI 229
Query: 269 WSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNE 328
WSLG++ +E+A+G PP A PM + L I
Sbjct: 230 WSLGITAIELAMG----EPPYADL---------------------HPMKVLFL---IPKN 261
Query: 329 PPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
PPP+L G FS FK+FV+ CL+++P R K L+ H +IRKA+
Sbjct: 262 PPPQL-EGPFSRPFKEFVNLCLQRDPANRPSAKELLKHPFIRKAK 305
>UniRef50_A5DK74 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 414
Score = 135 bits (326), Expect = 2e-30
Identities = 95/287 (33%), Positives = 155/287 (54%), Gaps = 34/287 (11%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
+G+GN G V K K +G ++A K+++L+ +++E++ L +IV + +F
Sbjct: 11 IGRGNFGDVYKAACKRSGKVVAVKVVNLDESLEDMFFMVQEIQFLSLMRSPYIVQYLESF 70
Query: 156 YSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKP 215
+ + I MEY GGS+ +L+ + E+I I VL GLSYL K +HRDVK
Sbjct: 71 VENSNMWIIMEYCGGGSVADVLRYCKKFDENIAAYIIKYVLLGLSYLH-KQKTVHRDVKL 129
Query: 216 SNILVNSNGEIKICDFGVSGQL--IDSMANSFVGTRSYMSPERLQGTH--YSVQSDIWSL 271
+N+LV ++G IK+ DFGVSG++ + ++FVGT +M+PE + + Y+ ++DIWS
Sbjct: 130 ANVLVTTDGTIKLADFGVSGEMSFTTNKRSTFVGTPYWMAPEVIVHSKLGYNEKADIWST 189
Query: 272 GLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPP 331
G++ +E+ G PP A D+ P ++L I + PP
Sbjct: 190 GITTIELIKG----DPPLA------------DYDP------------MKILFKIPKQEPP 221
Query: 332 KLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVD 378
L +SDE K F+++CL KNP +R+ L++H +I A AE+ D
Sbjct: 222 LLTGDKYSDELKGFLEKCLVKNPRKRSSSTELLDHPFIGIA-AEQQD 267
>UniRef50_UPI0000D5577B Cluster: PREDICTED: similar to STE20-like
kinase; n=1; Tribolium castaneum|Rep: PREDICTED: similar
to STE20-like kinase - Tribolium castaneum
Length = 1274
Score = 134 bits (325), Expect = 3e-30
Identities = 92/292 (31%), Positives = 149/292 (51%), Gaps = 39/292 (13%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146
++ ++ +GELG G G V K +HK TG + A K+ L+ + + +I E+ +L EC
Sbjct: 34 EEFWDMIGELGDGAYGKVYKAQHKHTGQLAAAKMCRLDGEDDLSDFMI-EIDILTECKHP 92
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDK 205
+IV + AF + ++ + +EY DGG+LD I+ + + + E + + + KGL +L
Sbjct: 93 NIVELHEAFQKEQQLWMLIEYCDGGALDSIMTELEKPLTELQIAYVCQNMCKGLEFLHKN 152
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSP-----ERLQ 258
H I HRD+K N+L+ G +K+ DFGVS + +M ++F+GT +M+P E +
Sbjct: 153 HVI-HRDLKAGNVLLTMEGGVKLADFGVSAKNKSTMQKHDTFIGTPYWMAPEVVLCETFR 211
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
Y + D+WS+G++L+E A + PP N + SP
Sbjct: 212 DNPYDFKVDVWSMGITLIEFA----QMEPP------------NHEMSP------------ 243
Query: 319 FELLDYIVNEPPPKLPS-GIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
+L I PPKL +S EF DFV CL K+P +R L+ H +I
Sbjct: 244 MRVLLKIQKSDPPKLEQPSKWSKEFNDFVSNCLVKDPQKRPTCDELLKHPFI 295
>UniRef50_A6QQ50 Cluster: MAP4K1 protein; n=1; Bos taurus|Rep:
MAP4K1 protein - Bos taurus (Bovine)
Length = 847
Score = 134 bits (325), Expect = 3e-30
Identities = 85/255 (33%), Positives = 140/255 (54%), Gaps = 12/255 (4%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
D ++ L LG G G V K R K TG ++A K++ +E + + +E+ +L C A+
Sbjct: 42 DHYDLLQRLGGGTYGEVFKAREKVTGDLVALKMVKMEPDDDVST-LQKEILILKTCRHAN 100
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
IV ++G++ ++ ICME+ GSL I + G + E + + VL+GL+YL +
Sbjct: 101 IVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCREVLQGLAYLHSQKK 160
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPE----RLQGTH 261
I HRD+K +NIL+N GE+++ DFG+S Q+ ++A SF+GT +M+PE L+G
Sbjct: 161 I-HRDIKGANILINDAGEVRLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKG-G 218
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIF-E 320
Y+ DIWSLG++ +E+A + P P D L +F + P + + + A F
Sbjct: 219 YNELCDIWSLGITAIELA-ELQP-PLFDVHPLRVLFLMTKSGYQPPRLKDKGKWSAAFHN 276
Query: 321 LLDYIVNEPPPKLPS 335
+ + + P K PS
Sbjct: 277 FVKVTLTKSPKKRPS 291
>UniRef50_A2EWJ0 Cluster: STE family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: STE family protein kinase
- Trichomonas vaginalis G3
Length = 385
Score = 134 bits (325), Expect = 3e-30
Identities = 75/198 (37%), Positives = 122/198 (61%), Gaps = 5/198 (2%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148
DF++ +G+G+ G+V K +K TG +A K I LE +I RE+ +L C ++
Sbjct: 12 DFQQCEIIGRGSFGIVFKAIYKKTGQTVAIKEIDLEKTSDELTEIQREIDMLRVCKSEYV 71
Query: 149 VGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
V G+ D ++ I MEYM GGS+ DLI + ++PE+ + + +L L++L K
Sbjct: 72 VSCEGSTLVDSKLWIVMEYMGGGSIRDLI--QIRKMPENTIAIVLKQILLALNFLH-KGR 128
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQL-IDSMANSFVGTRSYMSPERLQGTHYSVQS 266
+HRD+K +NIL++++G+IK+ DFGV+ L + A +FVGT +M+PE + Y+ +
Sbjct: 129 KIHRDIKAANILLSNDGDIKLADFGVASSLEARTKAYTFVGTPFWMAPEIIAEEGYNEKC 188
Query: 267 DIWSLGLSLVEMAIGMYP 284
DIWSLG++ +E+A GM P
Sbjct: 189 DIWSLGITAIEVATGMPP 206
Score = 48.8 bits (111), Expect = 3e-04
Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 321 LLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKV 377
+L I PPP L G FS +FKDFV +CL K+P +R L+ H +I+ A+ + +
Sbjct: 215 VLMLIPQNPPPTL-QGDFSPQFKDFVSKCLVKDPTKRPSAAELLTHPFIKSAKKKDI 270
>UniRef50_A7P2X0 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 1393
Score = 134 bits (324), Expect = 4e-30
Identities = 92/282 (32%), Positives = 150/282 (53%), Gaps = 37/282 (13%)
Query: 95 ELGQGNGGVVMKVRHKSTGLIMARKLIHLE-VKPAIKKQIIRELKVLHECNFAHIVGFYG 153
E+G+G G V K G +A K + LE + I++E+ +L N +IV + G
Sbjct: 25 EIGKGAYGRVYKGLDLENGDFVAIKQVSLENIAQEDLNIIMQEIDLLKNLNHKNIVKYLG 84
Query: 154 AFYSDGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLSYLRDKHAIMHR 211
+ + + I +EY++ GSL I+K K G PES++ S VL+GL YL ++ ++HR
Sbjct: 85 SLKTRSHLHIILEYVENGSLANIIKPNKFGPFPESLVAVYISQVLEGLVYLHEQ-GVIHR 143
Query: 212 DVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTHYSVQSDIW 269
D+K +NIL G +K+ DFGV+ +L ++ N S VGT +M+PE ++ + SDIW
Sbjct: 144 DIKGANILTTKEGLVKLADFGVATKLTEADVNTHSVVGTPYWMAPEVIEMSGVCAASDIW 203
Query: 270 SLGLSLVEMAIGMYPIPP-PDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNE 328
S+G +++E+ + +PP D + + A+F +DH P
Sbjct: 204 SVGCTVIEL---LTCVPPYYDLQPMPALFRIVQDDHPP---------------------- 238
Query: 329 PPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370
+P G+ S + DF+ +C KK+ +R D KTL++H WIR
Sbjct: 239 ----IPDGL-STDITDFLRQCFKKDARQRPDAKTLLSHPWIR 275
>UniRef50_A5DHS1 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 981
Score = 134 bits (324), Expect = 4e-30
Identities = 86/275 (31%), Positives = 146/275 (53%), Gaps = 10/275 (3%)
Query: 14 PPGSIDTNPAATPSNMTPQLKSATANERQGLAGKSKTSIEALTERLEQIEMDDTQRRRIE 73
PPG SN ++ + ++ Q +S S A + Q + D+ +R+ +
Sbjct: 633 PPGLTKKEAPQKASNSEQVTRTGSQSQSQNQGSRSAGS--ASKQAALQKKRDEKKRKNHQ 690
Query: 74 VFLCQKEKIGELSDDD--FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKK 131
+ + + + I D + + L ++GQG G V K+TG +A K ++LE +P K+
Sbjct: 691 I-ISKLQSICSSGDPNQYYRDLVKIGQGASGGVYIAHEKTTGSTVAIKQMNLEQQPK-KE 748
Query: 132 QIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTI 191
II E+ V+ ++IV F ++ G++ + MEYM+GGSL I+ + + E +G +
Sbjct: 749 LIINEILVMKGSKHSNIVNFIDSYLLKGDLWVVMEYMEGGSLTEIVTHS-VMTEGQIGAV 807
Query: 192 TSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL--IDSMANSFVGTR 249
LKGL +L K ++HRD+K NIL++++G IK+ DFG Q+ I+ + VGT
Sbjct: 808 CRETLKGLKFLHSK-GVIHRDIKSDNILLSTDGNIKMTDFGFCAQINEINLKRTTMVGTP 866
Query: 250 SYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284
+M+PE + Y + DIWSLG+ ++EM G P
Sbjct: 867 YWMAPEVVSRKEYGPKVDIWSLGIMVIEMIEGEPP 901
>UniRef50_A5DH79 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 507
Score = 134 bits (324), Expect = 4e-30
Identities = 77/204 (37%), Positives = 115/204 (56%), Gaps = 5/204 (2%)
Query: 86 SDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNF 145
S D+ E E+G+G GVV + +++GL +A K I LE P I+RE++++ EC
Sbjct: 6 SADELEVCEEVGRGAFGVVYRGHVRASGLEVAIKQIDLENDPTDLLDILREIQIISECRL 65
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
I FYG F + ++ + ME+ DGGS+ IL+ E + I VL L YL D+
Sbjct: 66 PQITSFYGCFVKNYQLWVVMEFADGGSIFDILRPGPMKNEKTIAIILKEVLVALEYLHDQ 125
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTH-- 261
I HRD+K NIL+ G +K+ DFGVS QL S N+ VGT +M+PE + ++
Sbjct: 126 GKI-HRDLKSQNILLTRLGNVKLTDFGVSAQLSSNFSRRNTTVGTPYWMAPEVILNSNGG 184
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPI 285
+S ++D+WSLG E+ G P+
Sbjct: 185 HSFKADLWSLGCCAYELVTGKPPL 208
>UniRef50_UPI00004998B6 Cluster: cell division control protein 7;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: cell division
control protein 7 - Entamoeba histolytica HM-1:IMSS
Length = 1760
Score = 134 bits (323), Expect = 5e-30
Identities = 89/285 (31%), Positives = 150/285 (52%), Gaps = 37/285 (12%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F +G+G G V + + +G +A K + + K ++ K+++ E+++L + HIV
Sbjct: 420 FSIANSIGRGAYGEVFQGMNADSGEFVAIKQMKVN-KKSVMKEVMEEIRLLKKLKHKHIV 478
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+ + S G + I MEYM+ GSL I+KK + ES+ VL GL+++ D+ I+
Sbjct: 479 RYIASTESHGFLYIIMEYMESGSLLNIVKKFNHLNESLSAKYIHQVLDGLAFIHDQ-GIV 537
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSF------VGTRSYMSPERLQGTHYS 263
HRD+K +NILV +G +KI DFGVS Q+ + +GT ++M+PE +Q +
Sbjct: 538 HRDIKAANILVAKDGSVKIADFGVSVQMNGNEKQEGGSDEDPIGTPNWMAPEVIQMQGTT 597
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLD 323
V++DIW+LG +++E+ G P D AA++ N+D+ P
Sbjct: 598 VKADIWALGCTIIELITGNPPY--YDLNPTAALYKIVNDDYPP----------------- 638
Query: 324 YIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEW 368
PS + S + KDF+ C K+NP++RA + L+ H+W
Sbjct: 639 ---------FPSTV-SVQLKDFLFSCFKRNPNQRASSRELLKHKW 673
>UniRef50_Q54RV3 Cluster: Putative uncharacterized protein pakG;
n=1; Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein pakG - Dictyostelium discoideum
AX4
Length = 1179
Score = 134 bits (323), Expect = 5e-30
Identities = 90/281 (32%), Positives = 141/281 (50%), Gaps = 42/281 (14%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
LG G+ G V K HK T ++A K I ++ I+K E+ +L +C +IV ++G+
Sbjct: 145 LGTGSYGTVYKAIHKDTNFVLAIKSIPIKESEEIEK----EISILKKCKSQNIVSYFGSG 200
Query: 156 YSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVK 214
+ I MEY S+ D++ + E + I LKGL YL + I+HRD+K
Sbjct: 201 QQGDNLWILMEYCSANSIRDMLELTEKSLTEKQISVILQQALKGLHYLHQSN-IIHRDIK 259
Query: 215 PSNILVNSNGEIKICDFGVSGQLIDSM---ANSFVGTRSYMSPERLQGTHYSVQSDIWSL 271
+NIL+N + +K+ DFGVS QL DS+ A+ VGT +M+PE ++ +Y+ + DIWSL
Sbjct: 260 AANILINEDAIVKLADFGVSSQLEDSLRGEASQLVGTPLWMAPEIIKRQNYNNKCDIWSL 319
Query: 272 GLSLVEMAIG---MYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNE 328
G++ +EMA +Y +PP A + PN P
Sbjct: 320 GITAIEMAESFPPLYTMPPTRAMLM---------------IPNKP--------------- 349
Query: 329 PPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
PP FS E DF+ +C +K+P++R L+ H ++
Sbjct: 350 PPTLSKPHHFSKELNDFIGQCCQKDPEKRPSAIELLTHPFL 390
>UniRef50_Q5AI03 Cluster: Likely protein kinase; n=2;
Saccharomycetales|Rep: Likely protein kinase - Candida
albicans (Yeast)
Length = 469
Score = 134 bits (323), Expect = 5e-30
Identities = 98/306 (32%), Positives = 151/306 (49%), Gaps = 53/306 (17%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
+G+GN G V + + ST ++A K+++L+ P KQII+E+ L +I+ + +F
Sbjct: 37 IGRGNFGDVYRAQQVSTNRLVAIKVVNLDESPDDIKQIIKEIHFLSRLRNPYIIRYIESF 96
Query: 156 YSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKP 215
+ + I MEY GGS +LK ++PE I+G I VL GL YL +H + HRD+K
Sbjct: 97 SQEYNMYIVMEYCGGGSCSDLLKYHKKLPEEIVGYIIHRVLLGLQYLHQEHKV-HRDIKS 155
Query: 216 SNILVNSNGEIKICDFGVSGQ--LIDSMANSFVGTRSYMSPE------RLQG-------- 259
+NIL+ G++K+ DFGVS + + N+FVGT +M+PE ++G
Sbjct: 156 ANILLTELGQVKLGDFGVSTEITMTKMKKNTFVGTPFWMAPEVITRAKLIEGNVKNCANS 215
Query: 260 --------THYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPN 311
T Y+ ++DIWS G++ +E+ G P+ D
Sbjct: 216 NGNYNGGNTGYNEKADIWSTGITTIELVTGSPPLSQYD---------------------- 253
Query: 312 SPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
P+ I L D I + PP L FSD K FV CL K PD+R+ L+ H++ +
Sbjct: 254 ---PLKI--LFD-IPKKRPPSLSGIDFSDNIKSFVKHCLIKEPDKRSSATALLQHKFFKA 307
Query: 372 AEAEKV 377
E V
Sbjct: 308 CVTEDV 313
>UniRef50_UPI000065E60F Cluster: STE20-like serine/threonine-protein
kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related
serine/threonine-protein kinase) (STE20-related kinase)
(hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor
antigen se20-9).; n=1; Takifugu rubripes|Rep: STE20-like
serine/threonine-protein kinase (EC 2.7.11.1)
(STE20-like kinase) (STE20-related
serine/threonine-protein kinase) (STE20-related kinase)
(hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor
antigen se20-9). - Takifugu rubripes
Length = 1128
Score = 133 bits (321), Expect = 9e-30
Identities = 89/279 (31%), Positives = 151/279 (54%), Gaps = 37/279 (13%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146
++ ++ +GELG G G V K ++K G + A K+I + + ++ ++ E+ +L C+
Sbjct: 31 EEIWDIIGELGDGAFGKVFKAQNKQNGTLAAAKVIDTKTEDELEDYMV-EIDILASCDHH 89
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDK 205
HIV AFY +G++ I +E+ GG++D I+ + R + E + + L+ L YL +
Sbjct: 90 HIVKLLDAFYFEGKLWILIEFCAGGAVDAIMLELERPLTEPQIRVVCRQTLEALIYLHE- 148
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPERL-----Q 258
+ I+HRD+K NIL++ NGE+K+ DFGVS + ++ +SF+GT +M+PE + +
Sbjct: 149 NKIIHRDLKAGNILLSLNGEVKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETSK 208
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
Y ++DIWSLG++L+E+A I PP+ + PM +
Sbjct: 209 DRPYDYKADIWSLGVTLIELA----QIEPPN---------------------HEMNPMRV 243
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDER 357
LL +EPP + +S EF DF+ + L KN D R
Sbjct: 244 --LLKIAKSEPPTLMHPSRWSPEFNDFLRKALDKNVDNR 280
>UniRef50_Q6DDZ8 Cluster: MGC81192 protein; n=1; Xenopus laevis|Rep:
MGC81192 protein - Xenopus laevis (African clawed frog)
Length = 1270
Score = 133 bits (321), Expect = 9e-30
Identities = 98/303 (32%), Positives = 155/303 (51%), Gaps = 47/303 (15%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE-CNFAHI 148
FE + +G G G V K RH TG + A K+ ++V +++I +E+ +L + + +I
Sbjct: 25 FELVEVVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTEDEEEEIKQEINMLKKYSHHRNI 82
Query: 149 VGFYGAFY------SDGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLS 200
+YGAF +D ++ + ME+ GS+ ++K K + E + I +L+GLS
Sbjct: 83 ATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLS 142
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL- 257
+L H ++HRD+K N+L+ N E+K+ DFGVS QL ++ N+F+GT +M+PE +
Sbjct: 143 HLH-AHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIA 201
Query: 258 ----QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
Y +SDIWSLG++ +EMA G P+ D + A+F
Sbjct: 202 CDENPDATYDYRSDIWSLGITAIEMAEGAPPL--CDMHPMRALF---------------- 243
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
I PPPKL S +S +F DF+D CL KN R + L+ H +IR
Sbjct: 244 ----------LIPRNPPPKLKSKKWSKKFIDFIDTCLIKNYMSRPPTEPLLKHPFIRDQP 293
Query: 374 AEK 376
E+
Sbjct: 294 TER 296
>UniRef50_Q6C2G1 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 1158
Score = 133 bits (321), Expect = 9e-30
Identities = 94/299 (31%), Positives = 155/299 (51%), Gaps = 38/299 (12%)
Query: 91 EKLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKP--AIKKQIIRELKVLHECNFAH 147
+ LG+ LG+G V + + +TG +A K I L P I+ E+ +L N +
Sbjct: 51 QTLGDCLGKGAYASVYRALNWNTGEAVAVKRIKLSDVPKKGDVDTIMMEIDLLKNLNHPN 110
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
IV ++G + ++I +EY + GSL I +K G+ PE+++ VLKGL+YL ++
Sbjct: 111 IVKYHGFVKTQDTLNIILEYCENGSLHSICRKFGKFPENLVAVYMYQVLKGLAYLHEQ-G 169
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLI---DSMANSFVGTRSYMSPERLQGTHYSV 264
++HRD+K +NIL +G K+ DFGV+ I S+ N GT ++M+PE ++ +
Sbjct: 170 VIHRDIKGANILTTKDGNSKLADFGVATTTILATGSVENGVAGTPNWMAPEIIELNGATT 229
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDY 324
SDIWS+G +++E+ G P H+ GQ P A+F
Sbjct: 230 ASDIWSVGCTVIELLTGKPPY------------------HNLGQMP------AMFA---- 261
Query: 325 IVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA--EAEKVDIAG 381
IVN+ P P G S DF+ +C +K+P+ R K L+ H W+ +A ++E+ ++G
Sbjct: 262 IVNDDHPAFPEGA-SPAALDFLGQCFQKDPNLRVTAKKLLRHPWLAEARTDSERKHVSG 319
>UniRef50_Q92918 Cluster: Mitogen-activated protein kinase kinase
kinase kinase 1; n=15; Theria|Rep: Mitogen-activated
protein kinase kinase kinase kinase 1 - Homo sapiens
(Human)
Length = 833
Score = 132 bits (320), Expect = 1e-29
Identities = 84/255 (32%), Positives = 139/255 (54%), Gaps = 12/255 (4%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
D ++ L LG G G V K R K +G ++A K++ +E + + +E+ +L C A+
Sbjct: 15 DHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVST-LQKEILILKTCRHAN 73
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
IV ++G++ ++ ICME+ GSL I + G + E + + VL+GL+YL +
Sbjct: 74 IVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCREVLQGLAYLHSQKK 133
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPE----RLQGTH 261
I HRD+K +NIL+N GE+++ DFG+S Q+ ++A SF+GT +M+PE L+G
Sbjct: 134 I-HRDIKGANILINDAGEVRLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKG-G 191
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIF-E 320
Y+ DIWSLG++ +E+A + P P D L +F + P + + A F
Sbjct: 192 YNELCDIWSLGITAIELA-ELQP-PLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSAAFHN 249
Query: 321 LLDYIVNEPPPKLPS 335
+ + + P K PS
Sbjct: 250 FIKVTLTKSPKKRPS 264
>UniRef50_A0C9W0 Cluster: Chromosome undetermined scaffold_16, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_16,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 464
Score = 131 bits (317), Expect = 3e-29
Identities = 95/299 (31%), Positives = 157/299 (52%), Gaps = 33/299 (11%)
Query: 78 QKEKIGELSDDDFEKLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIK-KQIIR 135
++ + SD + GE LGQG G V+ K+ G IMA K + ++ + K +Q+ +
Sbjct: 54 ERHSLKSTSDIHNWEQGEVLGQGAFGKVVMGLQKN-GQIMAVKQVFIQNQIDDKVRQLQK 112
Query: 136 ELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAV 195
E+++L + +IV + G + I+I +EY+ GGS+ +L++ G E ++ T +
Sbjct: 113 EIEMLSKLQHPNIVRYMGCEQKNQFINIFLEYVSGGSVSTLLERFGCFRERLIKTYLKQI 172
Query: 196 LKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID---SMANSFVGTRSYM 252
L GLSYL K+ ++HRD+K NIL++++G K+ DFG S QL D S GT ++M
Sbjct: 173 LLGLSYLHAKN-VIHRDIKGGNILIDNSGRCKLADFGSSKQLNDITHDSIGSICGTPNFM 231
Query: 253 SPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNS 312
+PE + Y ++DIWSLG +++EMA G PP ++ AI
Sbjct: 232 APEVINQEQYGKKADIWSLGCTVIEMATGQ----PPYSEYKDAI---------------- 271
Query: 313 PRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
AI + PP +P + S E KDF+ +CL+ +P +RA L+ H ++ +
Sbjct: 272 ----AIMVKIGKSTKPPP--IPDQLQSTEAKDFLSKCLQIDPKKRATADELLKHPFLEE 324
>UniRef50_Q4PC98 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1352
Score = 131 bits (317), Expect = 3e-29
Identities = 94/297 (31%), Positives = 149/297 (50%), Gaps = 37/297 (12%)
Query: 82 IGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLH 141
+G + + +L +G+G G V + H TG +A K+++L+ I RE+ +L
Sbjct: 682 VGPPVNSVYRRLELVGRGAYGAVYRGVHVETGAAVALKVVNLDTPDDDVSDIQREVALLS 741
Query: 142 ECNFA---HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKG 198
+ A ++V ++G + E+ I M++ +GGS+ ++K AG I E I L
Sbjct: 742 QLREAASKNVVRYWGCWLKGPELWIVMDFAEGGSVRTLMK-AGAIAERYCAVIVRETLVA 800
Query: 199 LSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL----IDSMANSFVGTRSYMSP 254
L+YL K I+HRD+K +NIL+ S G I +CDFGV+ L + S ++FVGT +M+P
Sbjct: 801 LNYLH-KSGIIHRDIKAANILLTSTGRILLCDFGVAASLASNSVHSKRSTFVGTPYWMAP 859
Query: 255 ERL-QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
E + +G Y ++D+WSLG+++ EMA G P+ D + + I P S
Sbjct: 860 EVITEGKTYDQKADVWSLGITIYEMATGNPPL--ADVEQMRVIM----------LIPKSK 907
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370
P E G FS +DFV CL + P ERA + L +WI+
Sbjct: 908 PPRLPLE---------------GDFSPAMRDFVAACLNEEPKERATSEELTKLKWIK 949
>UniRef50_A3LT13 Cluster: Predicted protein; n=1; Pichia
stipitis|Rep: Predicted protein - Pichia stipitis
(Yeast)
Length = 806
Score = 131 bits (317), Expect = 3e-29
Identities = 85/283 (30%), Positives = 152/283 (53%), Gaps = 14/283 (4%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC-NFA 146
D +++ +G+G G+V K +K T ++A K+++L+ + + +E+K L E N
Sbjct: 3 DVYKRTEVIGRGKFGIVYKGYNKQTKQVVAIKVLNLDTEEDEVSDVQQEIKFLSELKNVP 62
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
++ +YG+F +D ++ I M+Y GGSL ILK +G E +G I +L LS + K
Sbjct: 63 NVTQYYGSFLNDTKLWIIMDYCAGGSLRTILK-SGVFEEKYIGVIVRELLLALSAVH-KL 120
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERL-QGTHYS 263
++HRD+K +N+L+ G + +CDFGV+ ++ + + GT +M+PE + +G Y+
Sbjct: 121 GVIHRDLKAANVLITKEGSVLLCDFGVAAKITSNALKRTTMAGTPYWMAPEVIRKGDTYN 180
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLD 323
++DIWSLG+++ E+A G P DA + +P + +A+ E +
Sbjct: 181 SKADIWSLGITIYEIATGNPPYCDKDANWAMQMI----SKSTPPRLEGREYSVALKECIA 236
Query: 324 YIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNH 366
++E P + PS D K + R K +P + LK L++H
Sbjct: 237 LCLDENPDERPSA--DDLLKCKLVRAYKNHP--KMILKELISH 275
>UniRef50_O22040 Cluster: Mitogen-activated protein kinase kinase
kinase ANP1; n=5; Arabidopsis thaliana|Rep:
Mitogen-activated protein kinase kinase kinase ANP1 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 666
Score = 131 bits (317), Expect = 3e-29
Identities = 77/222 (34%), Positives = 124/222 (55%), Gaps = 12/222 (5%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKK-------QIIRELKVLHECNFAHI 148
+G+G G V + +G ++A K + + A K+ ++ E+K+L + +I
Sbjct: 75 IGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNI 134
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
V + G D ++I +E++ GGS+ +L+K G PES++ T T +L GL YL + HAI
Sbjct: 135 VRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHN-HAI 193
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLID----SMANSFVGTRSYMSPERLQGTHYSV 264
MHRD+K +NILV++ G IK+ DFG S Q+ + + A S GT +M+PE + T +S
Sbjct: 194 MHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSF 253
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSP 306
+DIWS+G +++EM G P + A F G + H P
Sbjct: 254 SADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHPP 295
>UniRef50_Q4S8I5 Cluster: Chromosome 2 SCAF14705, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF14705, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 703
Score = 131 bits (316), Expect = 4e-29
Identities = 72/186 (38%), Positives = 114/186 (61%), Gaps = 19/186 (10%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKV-LHE 142
E+ DD E++ ELG+G GVV K+RH+ I V +K+++ +L + +
Sbjct: 387 EVKADDLEQIAELGRGAYGVVDKMRHR----------IRATVNTQEQKRLLMDLDISMRT 436
Query: 143 CNFAHIVGFYGAFYSDGEISICMEYMDGGSLDL----ILKKAGRIPESILGTITSAVLKG 198
+ + + FYGAF+ +G++ ICME MD SLD +++K IPE ILG I +++K
Sbjct: 437 VDCLYTITFYGAFFREGDVWICMELMDT-SLDKFYKQVVEKGLTIPEDILGKIAVSIVKA 495
Query: 199 LSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSF-VGTRSYMSPERL 257
L +L ++HRDVKPSN+L+N+ G++K+CDFG+SG L+DS+A + G + YM+ +
Sbjct: 496 LEHLHSSLQVIHRDVKPSNVLINTQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAVK-- 553
Query: 258 QGTHYS 263
G YS
Sbjct: 554 DGAQYS 559
Score = 111 bits (266), Expect = 4e-23
Identities = 57/149 (38%), Positives = 93/149 (62%), Gaps = 9/149 (6%)
Query: 121 IHLEVKPAIKKQIIRELKV-LHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDL---- 175
I V +K+++ +L + + + + + FYGA + +G++ ICME MD SLD
Sbjct: 73 IRATVNTQEQKRLLMDLDISMRTVDCLYTITFYGALFREGDVWICMELMDT-SLDKFYKQ 131
Query: 176 ILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSG 235
+++K IPE ILG I +++K L +L ++HRDVKPSN+L+N+ G++K+CDFG+SG
Sbjct: 132 VVEKGLTIPEDILGKIAVSIVKALEHLHSSLQVIHRDVKPSNVLINTQGQVKMCDFGISG 191
Query: 236 QLIDSMANSF-VGTRSYMSPERLQGTHYS 263
L+DS+A + G + YM+ + G YS
Sbjct: 192 YLVDSVAKTMDAGCKPYMAVK--DGAQYS 218
Score = 55.2 bits (127), Expect = 3e-06
Identities = 39/118 (33%), Positives = 56/118 (47%), Gaps = 6/118 (5%)
Query: 252 MSPERLQGTHYSVQSDIWSLGLSLVEMAIGMY-PIPPP--DAKTLAAIFGGQNEDHSPGQ 308
++PE Q Y+++SDIWSLG+++V + P+ P T +F +
Sbjct: 249 INPETNQ-KGYNIKSDIWSLGITMVNKVFASFLPMSSPLGGVFTRGVLFRLPSRGQIELA 307
Query: 309 APNSPRPM--AIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLM 364
P F+ L +V EP P+LP+ FS EF DF +CLKK ER LM
Sbjct: 308 ILRFPYDSWGTPFQQLKQVVEEPSPQLPADQFSPEFVDFSSQCLKKVSKERPTYAELM 365
Score = 42.3 bits (95), Expect = 0.022
Identities = 20/37 (54%), Positives = 27/37 (72%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKL 120
E+ DD E++ ELG+G GVV K+RH +GLIMA K+
Sbjct: 3 EVKADDLEQIAELGRGAYGVVDKMRHVPSGLIMAVKV 39
Score = 41.9 bits (94), Expect = 0.029
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 17/98 (17%)
Query: 252 MSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPN 311
++PE Q Y+++SDIWSLG+++ +P PD P +
Sbjct: 590 INPETNQ-KGYNIKSDIWSLGITMRRFVSSS--VPRPDRA---------GHLRFPYDSWG 637
Query: 312 SPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRC 349
+P F+ L +V EP P+LP+ FS EF DF +C
Sbjct: 638 TP-----FQQLKQVVEEPSPQLPADQFSPEFVDFSSQC 670
>UniRef50_Q9M269 Cluster: Serine/threonine-protein kinase-like
protein; n=3; Arabidopsis thaliana|Rep:
Serine/threonine-protein kinase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 648
Score = 131 bits (316), Expect = 4e-29
Identities = 94/319 (29%), Positives = 160/319 (50%), Gaps = 40/319 (12%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEV-KPAIKKQIIRELKVLHECNFAHIVGFYGA 154
+G G+ VV +H+S+GL +A K I ++ P ++ +++E+ +L + +I+ FY A
Sbjct: 16 IGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISILSTIDHPNIIRFYEA 75
Query: 155 FYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVK 214
+ I + +EY GG L + + G++PE++ + GL L++KH I HRD+K
Sbjct: 76 IETGDRIFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQEKHFI-HRDLK 134
Query: 215 PSNILVNSNGE---IKICDFGVSGQLI-DSMANSFVGTRSYMSPERLQGTHYSVQSDIWS 270
P N+L++S +KI DFG + L +SMA +F G+ YM+PE ++ Y ++D+WS
Sbjct: 135 PQNLLLSSKEVTPLLKIGDFGFARSLTPESMAETFCGSPLYMAPEIIRNQKYDAKADLWS 194
Query: 271 LGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPP 330
G L ++ G PP F G N +L IV +
Sbjct: 195 AGAILFQLVTGK---PP---------FDGNNH----------------IQLFHNIVRDTE 226
Query: 331 PKLPSGIFSDEFKDFVDRC---LKKNPDERADLKTLMNHEWIRK-AEAEKVDIAGW-VCK 385
K P ++ D VD C L++NP ER + NH ++R+ + V+ +G+ C
Sbjct: 227 LKFPEDTRNEIHPDCVDLCRSLLRRNPIERLTFREFFNHMFLREPRQIPDVEHSGFSTCT 286
Query: 386 TMDLMPST-PNSNVSPFSS 403
L+PS P+++ + F S
Sbjct: 287 GKSLLPSAQPSTSTNRFKS 305
>UniRef50_Q59SB5 Cluster: Likely protein kinase; n=4;
Saccharomycetales|Rep: Likely protein kinase - Candida
albicans (Yeast)
Length = 556
Score = 131 bits (316), Expect = 4e-29
Identities = 98/293 (33%), Positives = 153/293 (52%), Gaps = 31/293 (10%)
Query: 86 SDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNF 145
S ++ E E+G+G GVV + KST +A K I LE +I +E++++ EC+
Sbjct: 8 SSEELEVYEEVGRGGFGVVYRGIIKSTNQEVAIKQIDLEKDSTDLIEINKEIQIISECHC 67
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
I + G+F + ++ + ME++DGGS+ +LK E I+ I +L L+YL ++
Sbjct: 68 QQITSYMGSFVKNYKLWVIMEFIDGGSIFELLKPGPIDDEKIVSFILYEILLALNYLHNQ 127
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTH-- 261
I HRD+K NIL++ G+IK+ DFGVS QL S N+ VGT +M+PE + +
Sbjct: 128 GKI-HRDLKSQNILISKTGDIKLTDFGVSTQLSSNFSKRNTTVGTPYWMAPEVIVNNNGG 186
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPP--PDAKTLAAIFGGQ-NEDHSPGQAPNSPRPMAI 318
+S ++DIWSLG EM G P+ P + L I Q N+D
Sbjct: 187 HSYKADIWSLGCCCYEMFTGKPPLQSKYPPMRALRLISKCQKNQD--------------F 232
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
+L++ +NE S EFKDF+ +C ++P RA L+ H++I K
Sbjct: 233 IKLIE--LNELD-------ISWEFKDFLHQCFIEDPKLRASASKLLKHKFITK 276
>UniRef50_UPI0001509E5E Cluster: Streptococcal surface antigen
repeat family protein; n=1; Tetrahymena thermophila
SB210|Rep: Streptococcal surface antigen repeat family
protein - Tetrahymena thermophila SB210
Length = 739
Score = 130 bits (315), Expect = 5e-29
Identities = 89/298 (29%), Positives = 145/298 (48%), Gaps = 25/298 (8%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE--VKPAIKKQIIRELKVLH 141
EL DF+ L LG+G G V K + + TG I A K + + +K + KQI E+KV++
Sbjct: 27 ELKTSDFQVLDRLGKGAFGKVYKTKLQKTGQIFALKQMEKQQILKQGMVKQIQTEVKVMY 86
Query: 142 ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201
+ +I+ Y F D I + +EY GG L L K GR E+ + + ++ + Y
Sbjct: 87 SLDHPNIIKLYNHFEEDAYIYLMIEYASGGQLWQKLTKEGRFDENTVKRYMADIILAVEY 146
Query: 202 LRDKH-AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGT 260
L ++ I+HRD+KP N++++ NG +K+ DFG S + + ++ GT Y++PE +
Sbjct: 147 LHSQNPPIIHRDIKPENLILDENGRVKLVDFGWS-NFKNRLRMTYCGTLDYLAPEMILEL 205
Query: 261 HYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFE 320
+ + DIWSLG+ + E+ G P P +N + QA +
Sbjct: 206 GHDEKLDIWSLGVLIFELITGKAPFAPK----------VENANIDQNQARQILEDNILKV 255
Query: 321 LLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEW-IRKAEAEKV 377
LDY P+ F KD V+ KK P++R L + H W I ++E + +
Sbjct: 256 KLDY---------PND-FPQLAKDLVNNLCKKEPNQRKTLPEIKKHPWFIIESEGKNI 303
>UniRef50_Q24C63 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 381
Score = 130 bits (315), Expect = 5e-29
Identities = 67/140 (47%), Positives = 96/140 (68%), Gaps = 14/140 (10%)
Query: 159 GEISICMEYMDGGSLDLILKKAGRIPESILGTI------------TSAVLKGLSYLRDKH 206
G+I+I +EYMD G+L ++KK RIPE L + VLKGL YL
Sbjct: 166 GKITIALEYMDMGTLGDLVKKFSRIPEVQLYLLLIDYLLQYLFLNLKKVLKGLEYLHKTM 225
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSV 264
++HRD+KPSN+LVNS+G +KI DFGVSG++ +++ NS+VGT YMSPERLQG +YS
Sbjct: 226 KVIHRDIKPSNLLVNSSGIVKIADFGVSGKINHTLSTKNSWVGTVQYMSPERLQGNNYSS 285
Query: 265 QSDIWSLGLSLVEMAIGMYP 284
+D+W+LG++++E+A+G P
Sbjct: 286 DTDLWALGITILELALGKMP 305
>UniRef50_A2DLZ6 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 972
Score = 130 bits (315), Expect = 5e-29
Identities = 93/294 (31%), Positives = 151/294 (51%), Gaps = 35/294 (11%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH-LEVKPAIKKQIIRELKVLHECNFA 146
+++ + ++G+G+ G V K R K TG ++A K+I+ L RE+ +L + N
Sbjct: 2 ENYHLIQQIGEGSFGRVYKARRKFTGRLVAIKMINKLGQSKDDLTSFKREINILKKVNHP 61
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
HI+ F SD + ++ E + G L I+ +PE +L T+ + + L+YL K+
Sbjct: 62 HIMRMLDMFESDTDFNVVSE-LARGDLFQIIDDNQTLPEDVLKTVAAQLTSALAYLH-KN 119
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYSV 264
I+HRD+KP NIL+ + G +K+CDFG + L + NS GT YM+PE +Q Y
Sbjct: 120 KIIHRDMKPQNILITNKGALKLCDFGFARALSSTTLFLNSIKGTPLYMAPELVQEQRYDE 179
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDY 324
+ D+WSLG+ L E+ F GQ P NS I++L+
Sbjct: 180 KIDVWSLGIILYEL------------------FYGQ-----PPFFTNS-----IYKLIQM 211
Query: 325 IVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVD 378
IVN+P + P G S+ FK F+ + L+K+P +R + L+ H +I + + D
Sbjct: 212 IVNDPI-QWP-GPISENFKGFLLKMLQKDPAQRVSCEELLQHPFIADVKLQDFD 263
>UniRef50_UPI0000E4894F Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 610
Score = 130 bits (314), Expect = 6e-29
Identities = 87/271 (32%), Positives = 144/271 (53%), Gaps = 15/271 (5%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR-ELKVLHECNFA 146
+DFE L +G G G V K R + G + A K+I +E P II+ E+ ++ +C A
Sbjct: 16 EDFELLQRIGSGTYGDVYKARMTAAGTLSAIKVIKIE--PGDDFTIIQQEILMMKDCRHA 73
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
+IVG++G++ ++ I MEY GGSL I G + E + + L GL+Y+
Sbjct: 74 NIVGYFGSYLRREKLWIAMEYCGGGSLQDIYHMTGHLAELQIAYVCQQTLTGLAYMHTL- 132
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL---QGTH 261
MHRD+K +NIL+ +G++K+ DFGVS Q+ ++A SF+GT +M+PE +
Sbjct: 133 GKMHRDIKGANILLTDDGDVKLADFGVSAQITQTIAKRKSFIGTPYWMAPEVAAVERKGG 192
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFE- 320
Y Q DIW++G++ +E+A + P P D + A+F + P + + + IF
Sbjct: 193 YDFQCDIWAVGITAIELA-ELQP-PMFDLHPMRALFLMSKSNFVPPKLKDKNKWSPIFHA 250
Query: 321 LLDYIVNEPPPKLPSG---IFSDEFKDFVDR 348
+ + + P K P+ + F+D +DR
Sbjct: 251 FIKTALIKNPKKRPTASKLLQHPYFQDNIDR 281
>UniRef50_Q381A7 Cluster: Mitogen activated protein kinase,
putative; n=4; Trypanosoma|Rep: Mitogen activated
protein kinase, putative - Trypanosoma brucei
Length = 657
Score = 130 bits (314), Expect = 6e-29
Identities = 89/286 (31%), Positives = 146/286 (51%), Gaps = 13/286 (4%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMA-RKLIHLEVKPAIKKQIIRELKVLHECNFA 146
D +E LG LG+G GVV+K RH++T I+A +K E ++K +RE++VL +
Sbjct: 2 DAYETLGMLGEGTYGVVVKARHRATSRIVAIKKYKQAEDDDHVRKTSLREVRVLKQLRHP 61
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLIL-KKAGRIPESILGTITSAVLKGLSYLRDK 205
+++ F DG++ + EY++ L LI KK G P+ + T +L G+SY
Sbjct: 62 NVIALLDVFRRDGKLYLVFEYVENTILQLIEEKKYGLSPDEVR-RYTFQLLNGVSYCH-A 119
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQL-IDSMANSFVGTRSYMSPERLQG-THYS 263
H I+HRDVKP NILV+ +G +K+CDFG + QL +V TR Y +PE L G Y
Sbjct: 120 HNIIHRDVKPENILVSRDGVLKLCDFGFARQLSCRGNYTEYVATRWYRAPELLVGDVSYG 179
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLD 323
D+W++G E++ G P+ P D+ + P Q ++ A++ +
Sbjct: 180 KAVDVWAIGCVFSELSDGQ-PLFPGDSDLDQLSLIMRACGPVPQQMVSTFEHNALYRRVT 238
Query: 324 Y----IVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMN 365
+ + + P+ + + +F+ CL+ +P ER LM+
Sbjct: 239 FPNVDVEETLQQRFPTA--ASPWLEFLTSCLRMDPVERPSCTALMS 282
>UniRef50_Q5KHJ6 Cluster: MAP kinase kinase kinase, putative; n=2;
Filobasidiella neoformans|Rep: MAP kinase kinase kinase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 1451
Score = 130 bits (314), Expect = 6e-29
Identities = 99/290 (34%), Positives = 151/290 (52%), Gaps = 42/290 (14%)
Query: 92 KLGEL-GQGNGGVVMKVRHKSTGLIMARKLIHL-EVKPAIKKQIIRELKVLHECNFAHIV 149
+LG+L G+G G V + + TG +A K I L + P+ I+ E+ +L N A+IV
Sbjct: 10 QLGDLLGRGASGNVYRALNFLTGETVAIKSISLLSLPPSSLPDIMSEIDLLKNLNHANIV 69
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+ G + I +EY + GSL ILKK G+ PES++ S VL+GL YL ++ ++
Sbjct: 70 KYKGFARDKENLWIILEYCENGSLQTILKKFGKFPESLVAVYISQVLEGLIYLHEQ-GVI 128
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQ----LIDSMANS------FVGTRSYMSPERLQG 259
HRD+K +NIL N +G +K+ DFGVS + ++D S VG+ +M+PE ++
Sbjct: 129 HRDIKGANILTNKDGSVKLADFGVSSRAPTAVLDQSGKSNDGEAEVVGSPYWMAPEVIEQ 188
Query: 260 THYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIF 319
+ S SDIWS+G +VE+ G PP +G D +P QA
Sbjct: 189 SGASTASDIWSVGCVVVELLEGK---PP---------YG----DLAPMQA---------- 222
Query: 320 ELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
L IV + ++P G S KDF+ C +K+P+ R K L+ H W+
Sbjct: 223 --LWRIVQDESMRIPEGA-SPIVKDFLYHCFQKDPNLRISAKKLLRHPWM 269
>UniRef50_A7RIM4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 924
Score = 130 bits (313), Expect = 8e-29
Identities = 84/291 (28%), Positives = 157/291 (53%), Gaps = 37/291 (12%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146
+ ++E +GELG G+ G V K +HK+ + A K+I + + ++ ++ E+ +L EC
Sbjct: 19 NSNWELVGELGDGSFGKVYKAQHKTESSLSAAKIIIVNDENELEDFMV-EIDILSECKHK 77
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLD-LILKKAGRIPESILGTITSAVLKGLSYLRDK 205
++VG + F DG++ + +E+ GG+LD L+L+ + E + +T + +GL +L +
Sbjct: 78 NLVGLFETFLHDGKLWMMLEFCSGGALDDLMLELERGLNEPEIRAVTRQLFEGLQFLHN- 136
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSP-----ERLQ 258
H ++HRD+K N+L+ S+G +K+ DFGVS + ++ ++F+GT +M+P E +
Sbjct: 137 HKVIHRDLKAGNLLLASDGNVKMADFGVSAKNKKTLQKRSTFIGTPYWMAPEVVVTETYK 196
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
Y ++DIWS G++L+E+A + PP+ ++ PM +
Sbjct: 197 DDPYDYKADIWSAGITLIELA----QMVPPN---------------------HNMHPMRV 231
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
L ++PP +S++ DF+ C+ KNPD RA ++ H +I
Sbjct: 232 --LFKIPKSDPPTFDNPNKWSNDLNDFLASCVVKNPDMRASATEMIKHPFI 280
>UniRef50_A3FQ10 Cluster: Protein kinase NPK2; n=2;
Cryptosporidium|Rep: Protein kinase NPK2 -
Cryptosporidium parvum Iowa II
Length = 384
Score = 130 bits (313), Expect = 8e-29
Identities = 104/323 (32%), Positives = 159/323 (49%), Gaps = 40/323 (12%)
Query: 85 LSDDDFE-KLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC 143
+S DFE LG G VV HK +G I+A K I++ + Q+ E+
Sbjct: 69 VSFGDFEVNPTPLGHGRSSVVFSAIHKLSGKIVAIKDIYVG-DILHQSQLSAEIHSWRLT 127
Query: 144 NFAHI-VGFYGAFYSDGEISIC--MEYMDGGSL-DLILKKAGR----------IPESILG 189
++ + V F GAF + +C MEYM+ G+L D++ K R + E+ L
Sbjct: 128 SYCPLLVQFLGAFIKPNKSVVCLVMEYMEFGTLSDILYKNLNRNLQSNETPEGVNENFLK 187
Query: 190 TITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA------- 242
I+ ++ GL+YL + I HRDVK +NIL+N +G +KI DFG+S +LID
Sbjct: 188 FISIQMVDGLAYLHQNNRI-HRDVKLNNILINQDGAVKISDFGIS-KLIDQNTTKDHNKN 245
Query: 243 -NSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQN 301
++FVGT+ YMSPERLQG YS SDIWSLG+ + E+A+G +P + I N
Sbjct: 246 VSTFVGTQIYMSPERLQGKSYSFSSDIWSLGICIYELAVGTHPFKNLSLFDMVYILCEDN 305
Query: 302 EDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSD-EFKDFVDRCLKKNPDERADL 360
++ P P L+ I+ P LP + + +F F+ CL+ +P +R
Sbjct: 306 TEN------GEPLP-----FLEKIIKRCP--LPEHLHKNPDFYAFLKGCLELDPLKRLTA 352
Query: 361 KTLMNHEWIRKAEAEKVDIAGWV 383
L +W+ + + W+
Sbjct: 353 LQLQGLKWLNFGTCNRYEFLAWL 375
>UniRef50_A2FCZ8 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 966
Score = 130 bits (313), Expect = 8e-29
Identities = 87/286 (30%), Positives = 150/286 (52%), Gaps = 35/286 (12%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH-LEVKPAIKKQIIRELKVLHECNFA 146
+D+ ++ ++G+G+ G V K R K TG ++A K+IH L + RE+ +L + +
Sbjct: 2 NDYYQIAQIGEGSFGRVYKARRKYTGRLVAIKMIHKLGQSQDSLASLRREINILQKVDHP 61
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
+I+ F ++ ++ + E + G L +++ +PES+L ++ + ++ L YL +
Sbjct: 62 NIMRLLEVFETNTDVCLVTE-LGRGDLFQVIQDQQTLPESVLKSVAAQLVSALLYLHQQR 120
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYSV 264
I+HRD+KP N+L++ N +K+CDFG + L ++ + NS GT YM+PE +Q Y+
Sbjct: 121 -IIHRDIKPQNVLISLNNTVKLCDFGFARALSNTTLVLNSIKGTPLYMAPELVQEQQYNE 179
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDY 324
+ DIWSLG L E+ G P AK++ ++L+
Sbjct: 180 KVDIWSLGAILYELYYGKTPF---SAKSI-------------------------YKLIQM 211
Query: 325 IVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370
IVN+ S S EFK F+ L+KNPD RA + L+ H +I+
Sbjct: 212 IVNDQIAW--SEPISPEFKGFLSIMLQKNPDRRASCEDLVKHPFIK 255
>UniRef50_A2E8U1 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 417
Score = 130 bits (313), Expect = 8e-29
Identities = 80/227 (35%), Positives = 123/227 (54%), Gaps = 4/227 (1%)
Query: 61 QIEMDDTQRRRIEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKL 120
Q E +T + V C LS DDF L E+G G G V + K TG + A K
Sbjct: 74 QSESKETFTTWLSVLSCCTIIPTPLSIDDFTILDEIGNGQYGKVKLAKKKDTGDLYAIKT 133
Query: 121 IHLEVKPAIKK--QIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILK 178
+H + ++K I+ E +L + + IV + AF SD + +CMEY+ GG+L ++
Sbjct: 134 LHKQKLVEMQKIHTIMCERNILSKASCPFIVQLHYAFQSDTKFYLCMEYVPGGTLFDHMR 193
Query: 179 KAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLI 238
+G IP L T+ + L +L H I++RD+KP N+L++ +G IK+ DFG S Q+
Sbjct: 194 LSGTIPPDALKLYTAELAIALHHLHVNH-IVYRDLKPENVLLDEDGHIKLTDFGSSKQID 252
Query: 239 DS-MANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284
+S +SF GT Y++PE ++G Y+ + D WSLG+ + EM P
Sbjct: 253 ESGTLHSFCGTPDYIAPEIVEGKPYTSKVDWWSLGILIYEMVFKAPP 299
>UniRef50_Q6BQI3 Cluster: Debaryomyces hansenii chromosome E of
strain CBS767 of Debaryomyces hansenii; n=2;
Eukaryota|Rep: Debaryomyces hansenii chromosome E of
strain CBS767 of Debaryomyces hansenii - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 547
Score = 130 bits (313), Expect = 8e-29
Identities = 74/204 (36%), Positives = 118/204 (57%), Gaps = 5/204 (2%)
Query: 86 SDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNF 145
S D+ + E+G+G GVV + K+T +A K I LE + ++ +E+ ++ EC
Sbjct: 7 SADELQVCEEVGRGGFGVVYRGVIKATNEEVAIKQIDLENEQTDLFEVNKEIMIISECRL 66
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
+ I +YG F + ++ + MEY++GGSL +LK E+++ I +L L YL D+
Sbjct: 67 SQITQYYGCFVNHYKLWVIMEYVNGGSLFELLKPGAVTDENVILIIAKEILIALEYLHDQ 126
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTH-- 261
I HRD+K NIL+N GE+K+ DFGVS QL S N+ VGT +M+PE + +
Sbjct: 127 GKI-HRDLKSQNILLNQTGEVKLTDFGVSTQLSSNFSRRNTTVGTPYWMAPEVILNNNGG 185
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPI 285
+S ++D+WSLG + E+ G P+
Sbjct: 186 HSYKADLWSLGCCVYELFTGKPPL 209
>UniRef50_Q03497 Cluster: Serine/threonine-protein kinase STE20;
n=2; Saccharomyces cerevisiae|Rep:
Serine/threonine-protein kinase STE20 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 939
Score = 130 bits (313), Expect = 8e-29
Identities = 87/283 (30%), Positives = 146/283 (51%), Gaps = 19/283 (6%)
Query: 13 LPPGSIDTNP----AATPSNMTPQLKSATANERQGLAGKSKTSIEALTERLEQIEMDDTQ 68
+PP T+P A TP + Q A A E +L++ L + + ++ +
Sbjct: 539 IPPTKSKTSPIISTAHTPQQVA-QSPKAPAQETVTTPTSKPAQARSLSKELNEKKREERE 597
Query: 69 RRRIEVFLCQKEKIGEL-SDDD----FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHL 123
RR+ +++ K+ E+ SD D + L ++GQG G V T + +A K ++L
Sbjct: 598 RRKKQLYA----KLNEICSDGDPSTKYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNL 653
Query: 124 EVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRI 183
E +P K+ II E+ V+ +IV F ++ G++ + MEYM+GGSL ++ +
Sbjct: 654 EKQPK-KELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHC-IL 711
Query: 184 PESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL--IDSM 241
E +G + L GL +L K ++HRD+K NIL++ G+IK+ DFG Q+ ++
Sbjct: 712 TEGQIGAVCRETLSGLEFLHSK-GVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLK 770
Query: 242 ANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284
+ VGT +M+PE + Y + DIWSLG+ ++EM G P
Sbjct: 771 RTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPP 813
>UniRef50_Q8IVW4 Cluster: Cyclin-dependent kinase-like 3; n=36;
Mammalia|Rep: Cyclin-dependent kinase-like 3 - Homo
sapiens (Human)
Length = 592
Score = 130 bits (313), Expect = 8e-29
Identities = 84/286 (29%), Positives = 142/286 (49%), Gaps = 5/286 (1%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+E LG++G+G+ G VMK +HK+TG I+A K+ + + ++ K +RE+K L + + ++V
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLV 63
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
F +I + E++D LD + + L +L+ + YL + I+
Sbjct: 64 NLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNN-II 122
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLI--DSMANSFVGTRSYMSPER-LQGTHYSVQS 266
HRD+KP NILV+ +G K+CDFG + L + +V TR Y +PE L+ T Y
Sbjct: 123 HRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPV 182
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPG-QAPNSPRPMAIFELLDYI 325
DIW+LG ++EMA G +P L + + SP Q S P+ +L +
Sbjct: 183 DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQV 242
Query: 326 VNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
+ + + D V CL+ +P +R L++HE+ +
Sbjct: 243 QHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTR 288
>UniRef50_UPI000059FEE9 Cluster: PREDICTED: similar to
Mitogen-activated protein kinase kinase kinase kinase 1
(MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1)
(MEKKK 1) (Hematopoietic progenitor kinase) isoform 2;
n=2; Canis lupus familiaris|Rep: PREDICTED: similar to
Mitogen-activated protein kinase kinase kinase kinase 1
(MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1)
(MEKKK 1) (Hematopoietic progenitor kinase) isoform 2 -
Canis familiaris
Length = 835
Score = 129 bits (312), Expect = 1e-28
Identities = 90/288 (31%), Positives = 149/288 (51%), Gaps = 34/288 (11%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
D ++ L LG G G V K R K TG ++A K++ +E + + +E+ +L C A+
Sbjct: 15 DHYDLLQRLGGGTYGEVFKARDKVTGDLVAVKMVKMEPDDDVST-LQKEILILKTCRHAN 73
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
IV ++G++ + ICME+ GSL I + G + E + + VL+GL+YL +
Sbjct: 74 IVAYHGSYLWLQKFWICMEFCGAGSLQDIYQVTGPLSELQISYVCREVLQGLAYLHSQKK 133
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPE----RLQGTH 261
I HRD+K +NIL+N G+ ++ DFG+S Q+ ++A SF+GT +M+PE L+G
Sbjct: 134 I-HRDIKGANILINDAGDFRLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKG-G 191
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
Y+ DIWSLG++ +E+A + PP +F P+ + L
Sbjct: 192 YNELCDIWSLGITAIELA----ELQPP-------LF--------------DVHPLRVLFL 226
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
+ +PP G +S F +FV L KNP +R +++H+ +
Sbjct: 227 MTKSGYQPPRLKEKGKWSAAFHNFVKVTLTKNPKKRPCATKMLSHQLV 274
>UniRef50_Q7ZUA2 Cluster: Mitogen-activated protein kinase kinase
kinase kinase 5; n=7; Euteleostomi|Rep:
Mitogen-activated protein kinase kinase kinase kinase 5
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 878
Score = 129 bits (311), Expect = 1e-28
Identities = 80/215 (37%), Positives = 123/215 (57%), Gaps = 11/215 (5%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR-ELKVLHECNFAH 147
DFE + +G G G V K R STG + A K+I LE P II+ E+ ++ EC +
Sbjct: 19 DFELIQRVGSGTYGDVYKARKISTGELAAVKIIKLE--PGDDFSIIQQEIFMVKECTHHN 76
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
IV ++G++ ++ ICMEY GGSL I G + E + + L+GL YL K
Sbjct: 77 IVAYFGSYLCREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLGYLHSK-G 135
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL---QGTHY 262
MHRD+K +NIL+ NG++K+ DFGV+ ++ +MA SF+GT +M+PE + Y
Sbjct: 136 KMHRDIKGANILLTDNGDVKLADFGVAAKITATMAKRKSFIGTPYWMAPEVAAVEKNGGY 195
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIF 297
+ DIW++G++ +E+A + P P D + A+F
Sbjct: 196 NHLCDIWAVGITSIELA-ELQP-PMFDLHPMRALF 228
>UniRef50_Q9LQM8 Cluster: F5D14.7 protein; n=2; Arabidopsis
thaliana|Rep: F5D14.7 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 305
Score = 129 bits (311), Expect = 1e-28
Identities = 74/204 (36%), Positives = 112/204 (54%), Gaps = 12/204 (5%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
+D EKL LGQG+GG V K RH+ T + A K++ +P + + E +L +
Sbjct: 46 NDLEKLSVLGQGSGGTVYKTRHRRTKTLYALKVL----RPNLNTTVTVEADILKRIESSF 101
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
I+ Y F S ++ ME M+ GSL L E ++ ++ + +L+GL YL+ K
Sbjct: 102 IIKCYAVFVSLYDLCFVMELMEKGSLHDALLAQQVFSEPMVSSLANRILQGLRYLQ-KMG 160
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQ------GTH 261
I+H D+KPSN+L+N GE+KI DFG S +++ GT +YMSPER+ G
Sbjct: 161 IVHGDIKPSNLLINKKGEVKIADFGAS-RIVAGGDYGSNGTCAYMSPERVDLEKWGFGGE 219
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPI 285
D+WSLG+ ++E IG YP+
Sbjct: 220 VGFAGDVWSLGVVVLECYIGRYPL 243
>UniRef50_Q0USU3 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1499
Score = 129 bits (311), Expect = 1e-28
Identities = 101/354 (28%), Positives = 168/354 (47%), Gaps = 38/354 (10%)
Query: 27 SNMTPQLKSATANERQGLAGKSKTSIEALTERLEQIEMDDTQRRRIEVFLCQKEKIGELS 86
S+ ++ A +N R A S+++ ++ + Q R E ++ + +
Sbjct: 3 SHAPNKVSHAASNSRSSQASTSQSNTPGHAKKSSSSSNHNGQPREREQRPSREGTAQKAA 62
Query: 87 DD-----DFEKLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLE-VKPAIKKQIIRELKV 139
D DF+ LG+ LG+G G V + + TG +A K + LE + A K + E+ +
Sbjct: 63 QDVAGLKDFQ-LGDCLGKGAFGSVYRALNWGTGETVAIKQVRLENLGAADLKNMEMEIDL 121
Query: 140 LHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGL 199
L N +IV + G S + I +EY + GSL I K G+ PE+++ S L GL
Sbjct: 122 LKNLNHPNIVKYNGFVRSSESLYIILEYCENGSLHSICKNFGKFPENLVALYMSQALHGL 181
Query: 200 SYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQG 259
YL ++ ++HRD+K +NIL G +K+ DFGV+ + +S VGT +M+PE ++
Sbjct: 182 LYLHEQ-GVIHRDIKGANILTTKEGLVKLADFGVATKQSGLDQSSVVGTPYWMAPEVIEL 240
Query: 260 THYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIF 319
+ + SDIWSLG +++E+ G P + + A+F N++H P P S P+
Sbjct: 241 SGATTSSDIWSLGCTVIELIEGKPPY--HKLQPMQALFRIVNDEHPP--IPGSASPL--- 293
Query: 320 ELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
++F+ C +KNP R K L+ H WI A+
Sbjct: 294 ----------------------LREFLMECFQKNPTLRISAKRLLKHPWIMSAK 325
>UniRef50_Q92212 Cluster: Serine/threonine-protein kinase CST20; n=1;
Candida albicans|Rep: Serine/threonine-protein kinase
CST20 - Candida albicans (Yeast)
Length = 1228
Score = 129 bits (311), Expect = 1e-28
Identities = 90/276 (32%), Positives = 150/276 (54%), Gaps = 16/276 (5%)
Query: 16 GSIDTNPAATPSNMTPQLKSATANERQGLAGKSKTSIEALTERLEQIEMDDTQRRRIEVF 75
G + + A+ SN+ P + G G AL + Q + ++ +R+ +++
Sbjct: 879 GQNNADTASGGSNIAPPVPVPNKKPPSGSGGGRDAKQAAL---IAQKKREEKKRKNLQI- 934
Query: 76 LCQKEKIGELSDDD--FEKLGELGQG-NGGVVMK--VRHKSTGLIMARKLIHLEVKPAIK 130
+ + + I D + + L ++GQG +GGV + VR KS I+A K ++LE +P K
Sbjct: 935 IAKLKTICNPGDPNELYVDLVKIGQGASGGVFLAHDVRDKSN--IVAIKQMNLEQQPK-K 991
Query: 131 KQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGT 190
+ II E+ V+ + +IV F ++ G++ + MEYM+GGSL I+ + + E +G
Sbjct: 992 ELIINEILVMKGSSHPNIVNFIDSYLLKGDLWVIMEYMEGGSLTDIVTHSV-MTEGQIGV 1050
Query: 191 ITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL--IDSMANSFVGT 248
+ LKGL +L K ++HRD+K NIL+N +G IKI DFG Q+ I+S + VGT
Sbjct: 1051 VCRETLKGLKFLHSK-GVIHRDIKSDNILLNMDGNIKITDFGFCAQINEINSKRITMVGT 1109
Query: 249 RSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284
+M+PE + Y + D+WSLG+ ++EM G P
Sbjct: 1110 PYWMAPEIVSRKEYGPKVDVWSLGIMIIEMLEGEPP 1145
>UniRef50_UPI0000498D8F Cluster: protein kinase; n=2; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 479
Score = 128 bits (310), Expect = 2e-28
Identities = 98/300 (32%), Positives = 151/300 (50%), Gaps = 38/300 (12%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F+ ++G+G GVV + K T A K I +E +I Q E+K++ +IV
Sbjct: 204 FDNWQQIGEGVSGVVFQCVDKKTKEERAVKKIKIE-DDSINLQ---EIKIMQTLKHPNIV 259
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLSYLRDKHA 207
GF+G F D + I ME+MD +L IL+ + + E + + + L Y+ H
Sbjct: 260 GFFGCFELDNYLYISMEFMDRNNLTAILEFFPSVAMNEPQIAYVARETNEALRYVHSFHR 319
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLI--DSMANSFVGTRSYMSPERLQGTHYSVQ 265
I HRD+K NIL+N NGE+K+ DFGVS QL S N+ VGT +M+PE ++G Y+
Sbjct: 320 I-HRDIKSDNILINHNGEVKLADFGVSVQLTKNKSKRNTIVGTPYWMAPEVIKGKDYNCL 378
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYI 325
D+WSLG+ EM G YP P D L A+F + + G P
Sbjct: 379 IDVWSLGIMCREMMEG-YP-PYMDDPPLRALF----QISTKGVPP--------------- 417
Query: 326 VNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGWVCK 385
+ +G +S E D+V+ CL NPD+R ++ + + + +KA K++ A +V +
Sbjct: 418 -------ITTGSWSKELLDYVNGCLSVNPDQRPSTESSVKNPFFQKA-CTKIEFADFVSR 469
>UniRef50_Q32NV8 Cluster: LOC443633 protein; n=6; Euteleostomi|Rep:
LOC443633 protein - Xenopus laevis (African clawed frog)
Length = 485
Score = 128 bits (310), Expect = 2e-28
Identities = 95/303 (31%), Positives = 154/303 (50%), Gaps = 47/303 (15%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE-CNFAHI 148
FE + +G G G V K RH TG + A K+ ++V +++I +E+ +L + + +I
Sbjct: 25 FELVELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNI 82
Query: 149 VGFYGAFYS------DGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLS 200
+YGAF D ++ + ME+ GS+ ++K K + E + I +L+GLS
Sbjct: 83 ATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLS 142
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL- 257
+L +H ++HRD+K N+L+ N E+K+ DFGVS QL ++ N+F+GT +M+PE +
Sbjct: 143 HLH-QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIA 201
Query: 258 ----QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
Y +SD+WSLG++ +EMA G P+ D + A+F
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL--CDMHPMRALF---------------- 243
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
I P P+L S +S +F+ F+D CL KN +R LM H +IR
Sbjct: 244 ----------LIPRNPAPRLKSKKWSKKFQSFIDSCLVKNHSQRPTTDQLMKHPFIRDQP 293
Query: 374 AEK 376
E+
Sbjct: 294 NER 296
>UniRef50_Q5BW36 Cluster: SJCHGC05877 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC05877 protein - Schistosoma
japonicum (Blood fluke)
Length = 522
Score = 128 bits (310), Expect = 2e-28
Identities = 70/221 (31%), Positives = 126/221 (57%), Gaps = 9/221 (4%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
++++ L +G G G V K H+ ++A K++ +++K I+ I +E+ L EC +
Sbjct: 12 EEYKILSPIGSGTYGDVFKAVHRERRTLVAVKVMKIDLKDDIRS-ICQEIHTLRECRHPN 70
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
IV FYG++ + ++ ICMEY G S+ D+ L + E + ++ L+GL+++ ++
Sbjct: 71 IVQFYGSYLRNNKLWICMEYCGGQSMQDIYLYTRRPLEEDCIAFVSRETLQGLNFMHNRG 130
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPE----RLQGT 260
I HRD+K +NIL+ +G +K+ DFGV+ QL S+A + +GT +M+PE +G+
Sbjct: 131 RI-HRDIKGANILLTDDGHVKVADFGVAAQLSTSIAKRTTLIGTPYWMAPEVASIECRGS 189
Query: 261 HYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQN 301
Y + DIW +G++ +E A P+ D + I G +N
Sbjct: 190 GYDGKCDIWGVGITAIEYAELQPPMFDLDPRKALQILGSRN 230
>UniRef50_Q55CA6 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 635
Score = 128 bits (310), Expect = 2e-28
Identities = 96/302 (31%), Positives = 144/302 (47%), Gaps = 37/302 (12%)
Query: 73 EVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHL-EVKPAIKK 131
E + K+ IG D +G+G V K + +G +A K ++
Sbjct: 64 ESMVASKKTIGAFVISDIA----IGKGAFATVFKGLNTLSGDFVAIKRFEKSKISNEQHS 119
Query: 132 QIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTI 191
+ E +L N +IV G ++ I I +EYM+ GSL IL G PES++
Sbjct: 120 SVSTEFDILQRLNHENIVRILGREENENYIYIFLEYMENGSLSTILNNFGTFPESLICNY 179
Query: 192 TSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLI--DSMANSFVGTR 249
VLKGL YL + ++HRD+K +NIL+N GE K+ DFG +G++I S VGT
Sbjct: 180 VENVLKGLVYLH-QEGVIHRDIKAANILINKAGEAKLSDFGTAGEIIKESDKRYSVVGTP 238
Query: 250 SYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQA 309
+M+PE ++ + + SDIWSLG +++E+ YP P D L A++ +D P
Sbjct: 239 YWMAPEVIEISGHCQVSDIWSLGCTIIEL-FTSYP-PYFDLNPLGAMYRICQDDRPP--- 293
Query: 310 PNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
LP I S E +F++RC K+ +ERA K L++H WI
Sbjct: 294 -----------------------LPDDI-SSELANFLERCFCKSTEERATAKELLSHPWI 329
Query: 370 RK 371
K
Sbjct: 330 TK 331
>UniRef50_A6YTD4 Cluster: NPK1-like kinase; n=1; Cucumis melo|Rep:
NPK1-like kinase - Cucumis melo (Muskmelon)
Length = 692
Score = 128 bits (309), Expect = 3e-28
Identities = 80/225 (35%), Positives = 124/225 (55%), Gaps = 13/225 (5%)
Query: 94 GEL-GQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKK-------QIIRELKVLHECNF 145
GEL G G G V + +G ++A K + + A K+ ++ E+K+L + +
Sbjct: 73 GELIGCGAFGRVYMGMNLGSGELLAVKQVLIAANGASKEKAQAQVQELEEEVKLLKDLSH 132
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
+IV + G D ++I +E++ GGS+ +L K G PE++L T T +L GL YL K
Sbjct: 133 PNIVRYLGTVREDDSLNILLEFVPGGSIASLLGKFGAFPEAVLRTYTKQLLLGLEYLH-K 191
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID----SMANSFVGTRSYMSPERLQGTH 261
+ IMHRD+K +NILV++ G IK+ DFG S Q+++ S A S GT +M+PE + T
Sbjct: 192 NGIMHRDIKGANILVDNKGCIKLADFGASKQVVELATISGAKSMKGTPYWMAPEVILQTG 251
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSP 306
+S +DIWS+G + +EMA G P + A G + H P
Sbjct: 252 HSFSADIWSVGCTFIEMATGKPPWSQQYQEVAALFHIGTTKSHPP 296
>UniRef50_Q4QA98 Cluster: Mitogen-activated protein kinase; n=8;
Trypanosomatidae|Rep: Mitogen-activated protein kinase -
Leishmania major
Length = 350
Score = 128 bits (309), Expect = 3e-28
Identities = 77/206 (37%), Positives = 113/206 (54%), Gaps = 5/206 (2%)
Query: 82 IGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEV-KPAIKKQIIRELKVL 140
+ ++ +D ELG+G+ G V +HK TG A K I + ++ + EL+ +
Sbjct: 65 MNKIKFEDLRIGSELGKGSQGKVRVAQHKITGEKYAMKYISFDGDSDDMRCALEAELRQV 124
Query: 141 HECNFAHIVGFYGAFYSDGEISICMEYMDGGSLD-LILKKAGRIPESILGTITSAVLKGL 199
++V Y AF+ DG + + +EYMD G+++ LI + E +L I + KGL
Sbjct: 125 AAVKHHNVVSSYEAFFRDGRLYVVLEYMDCGTMNNLIDRHPEGFSEDMLAYIARELFKGL 184
Query: 200 SYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLI--DSMANSFVGTRSYMSPERL 257
+L + I HRD+KP+N+L N+ GEIKI DFGV+ L D S G+ YMSPER+
Sbjct: 185 EFLHHLNMI-HRDIKPANVLANAKGEIKISDFGVAKTLSGGDLQTLSAQGSVPYMSPERI 243
Query: 258 QGTHYSVQSDIWSLGLSLVEMAIGMY 283
Q YS SDIWS GL++ E A Y
Sbjct: 244 QSKPYSFNSDIWSAGLTIAECAFREY 269
Score = 34.3 bits (75), Expect = 5.8
Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 338 FSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
FSDEFK+F++ CL+ R ++NH I+KA
Sbjct: 301 FSDEFKEFIELCLRPEA-TRPSATEMLNHSLIQKA 334
>UniRef50_O42625 Cluster: MAPKK kinase; n=6; Pezizomycotina|Rep:
MAPKK kinase - Neurospora crassa
Length = 666
Score = 128 bits (309), Expect = 3e-28
Identities = 92/274 (33%), Positives = 148/274 (54%), Gaps = 29/274 (10%)
Query: 45 AGKSKTSIEALTERLEQIEMDDTQRRRIEVFLCQKEKIGELSDDDFEKLGEL-GQGNGGV 103
+G + ++ A+ + + +D + ++ FL G+ DD G L GQG+ G
Sbjct: 349 SGTNNSADSAVIQEALAEDGEDAADKELQTFLA-----GDAWDDSMWMKGSLIGQGSFGS 403
Query: 104 VMKVRHKSTGLIMARKLIHLEV------KPAIKKQII----RELKVLHECNFAHIVGFYG 153
V H TG ++A K + A KK +I RE+ +L + +IV + G
Sbjct: 404 VYLALHAITGELLAVKQVETPAPGADSKNDARKKSMIEALKREITLLRDLQHPNIVQYLG 463
Query: 154 AFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDV 213
S ++I +EY+ GGS+ +L + G +PES++ + +L+GLSY+ ++ I+HRD+
Sbjct: 464 CSSSAEYLNIFLEYVPGGSVQTMLDQYGALPESLVRSFVRQILQGLSYVHNRD-IIHRDI 522
Query: 214 KPSNILVNSNGEIKICDFGVSGQL----IDSMAN------SFVGTRSYMSPERLQGTHYS 263
K +NILV++ G IKI DFG+S +L I + AN S G+ +M+PE ++ T Y+
Sbjct: 523 KGANILVDNKGTIKISDFGISKKLEATNILNGANNNKHRPSLQGSVFWMAPEVVKQTSYT 582
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIF 297
++DIWSLG +VEM G +P PD L AIF
Sbjct: 583 RKADIWSLGCLVVEMMTGTHPF--PDCTQLQAIF 614
>UniRef50_Q8IVH8 Cluster: Mitogen-activated protein kinase kinase
kinase kinase 3; n=46; Bilateria|Rep: Mitogen-activated
protein kinase kinase kinase kinase 3 - Homo sapiens
(Human)
Length = 894
Score = 128 bits (309), Expect = 3e-28
Identities = 89/288 (30%), Positives = 147/288 (51%), Gaps = 34/288 (11%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR-ELKVLHECNFA 146
+DFE + +G G G V K R+ +TG + A K+I LE P +++ E+ ++ +C
Sbjct: 14 EDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLE--PGEDFAVVQQEIIMMKDCKHP 71
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
+IV ++G++ ++ ICME+ GGSL I G + E + ++ L+GL YL K
Sbjct: 72 NIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSK- 130
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL---QGTH 261
MHRD+K +NIL+ NG +K+ DFGVS Q+ ++A SF+GT +M+PE +
Sbjct: 131 GKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGG 190
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
Y+ D+W++G++ +E+A + PP +F PM L
Sbjct: 191 YNQLCDLWAVGITAIELA----ELQPP-------MF--------------DLHPMRALFL 225
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
+ +PP +S+ F FV L KNP +R + L+ H ++
Sbjct: 226 MTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFV 273
>UniRef50_UPI0000563837 Cluster: serine/threonine kinase; n=1;
Giardia lamblia ATCC 50803|Rep: serine/threonine kinase
- Giardia lamblia ATCC 50803
Length = 527
Score = 128 bits (308), Expect = 3e-28
Identities = 86/285 (30%), Positives = 153/285 (53%), Gaps = 30/285 (10%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
FE L +G G+ G V + T I+A K I LE + +I E++++ + N +IV
Sbjct: 16 FELLSPIGSGSYGAVWQAFSVLTSEIVAVKRIPLESDTSA---LILEIQLMKKLNHPNIV 72
Query: 150 GFYGAFYS--DGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKH 206
+ G+F D E+ I +E+ G++ +++ + + E ++ L GL YL +H
Sbjct: 73 KYLGSFVDKVDDELWIILEFCSAGAISDLMRGCHKTLTEEQCSYTLASTLLGLRYLHKQH 132
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSV 264
I HRD+K +N+L++ + ++I DFGVS ++ +S A NS +GT ++SP++++G Y
Sbjct: 133 VI-HRDIKANNLLISEDASVRIADFGVSAEMQNSFAQRNSTIGTPYWLSPQQIKGEPYGF 191
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDY 324
++D+W+LG++ +E+ G P P + ++ A+ P P PM + +
Sbjct: 192 KADVWALGITAIELTEGK-P-PHSELTSMRAMI----------VIPRQP-PMKLKGRTNP 238
Query: 325 IVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
+P SD F DFVDRCL+ ++RA ++ L+ HE+I
Sbjct: 239 FTKQP--------HSDVFADFVDRCLQHAEEDRATVEELLQHEFI 275
>UniRef50_UPI0000498BDB Cluster: cell division control protein 7;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: cell division
control protein 7 - Entamoeba histolytica HM-1:IMSS
Length = 1071
Score = 128 bits (308), Expect = 3e-28
Identities = 85/285 (29%), Positives = 149/285 (52%), Gaps = 37/285 (12%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F +G+G G V + + +G +A K + + K ++ K+++ E+++L + HIV
Sbjct: 2 FSIANSIGRGAYGEVFQGMNADSGEFVAIKQMKVN-KKSVMKEVMEEIRLLKKLKHKHIV 60
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+ + S G + I MEYM+ GSL I+KK + ES+ VL GL+++ D+ I+
Sbjct: 61 RYIASTESHGFLYIIMEYMESGSLLNIVKKFNHLNESLSAKYIHQVLDGLAFIHDQ-GIV 119
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSF------VGTRSYMSPERLQGTHYS 263
HRD+K +NILV +G +KI DFGVS Q+ + +GT ++M+PE +Q +
Sbjct: 120 HRDIKAANILVAKDGSVKIADFGVSVQMNGNEKQETGSDEDPIGTPNWMAPEVIQMQGTT 179
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLD 323
V++DIW+LG +++E+ G P D AA++ N+D+ P PN+ P
Sbjct: 180 VKADIWALGCTVIELITGNPPY--YDLNPTAALYKIVNDDYPP--FPNTVSP-------- 227
Query: 324 YIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEW 368
+ ++ + C K++P++RA + L+ H+W
Sbjct: 228 -----------------QLREILFSCFKRDPNQRASSRDLLKHKW 255
>UniRef50_Q170F5 Cluster: P21-activated kinase, pak; n=2;
Coelomata|Rep: P21-activated kinase, pak - Aedes aegypti
(Yellowfever mosquito)
Length = 537
Score = 128 bits (308), Expect = 3e-28
Identities = 99/310 (31%), Positives = 157/310 (50%), Gaps = 36/310 (11%)
Query: 68 QRRRIEVFLCQKEKIGELSD--DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEV 125
QR E F + + D ++ E ++G+G+ G V KSTG +A K + L
Sbjct: 241 QRLTHEQFRAALQMVVSAGDPRENLENFTKIGEGSTGTVCIATDKSTGRQVAVKKMDLR- 299
Query: 126 KPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPE 185
K ++ + E+ ++ + + +IV Y +F + E+ + MEY++GG+L I+ + R+ E
Sbjct: 300 KQQRRELLFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGALTDIVTHS-RMDE 358
Query: 186 SILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN-- 243
+ T+ LK LSYL + ++HRD+K +IL+ S+G +K+ DFG Q+ +
Sbjct: 359 EQIATVCKQCLKALSYLHSQ-GVIHRDIKSDSILLASDGRVKLSDFGFCAQVSQELPKRK 417
Query: 244 SFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNED 303
S VGT +MSPE + Y + DIWSLG+ ++EM G PP F NE
Sbjct: 418 SLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMIDG----EPP-------FF---NE- 462
Query: 304 HSPGQAPNSPRPMAIFELLDYIVNEPPPKLP-SGIFSDEFKDFVDRCLKKNPDERADLKT 362
P QA R M PPPKL S S ++F+DR L ++P +RA
Sbjct: 463 -PPLQAMRRIRDM------------PPPKLKNSHKVSSRLQNFLDRMLVRDPVQRATAAE 509
Query: 363 LMNHEWIRKA 372
L+ H ++R+A
Sbjct: 510 LLAHPFLRQA 519
>UniRef50_Q7Z8J5 Cluster: MAP kinase kinase kinase; n=1; Yarrowia
lipolytica|Rep: MAP kinase kinase kinase - Yarrowia
lipolytica (Candida lipolytica)
Length = 944
Score = 128 bits (308), Expect = 3e-28
Identities = 94/297 (31%), Positives = 151/297 (50%), Gaps = 26/297 (8%)
Query: 15 PGSIDTNPAATPSNMTP-QLKSATANERQGLAGKSKTSIEALTERLEQIEMDDTQRRRIE 73
P + T +M P + +S++ ER KS SI A E L Q E +
Sbjct: 593 PSDLSMPQTLTRESMQPSRTQSSSQVERGSSLRKSTASIPATLETLSQQEEAASAAASAT 652
Query: 74 VFLCQKEKIGELSDDDF--EKL-------------GEL-GQGNGGVVMKVRHKSTGLIMA 117
L S+DD E++ G L GQG+ G V + TG +MA
Sbjct: 653 ASLVDPPHSATPSEDDMSDEQIIAMQSEAPKNWIKGTLIGQGSFGCVHLGMNSLTGELMA 712
Query: 118 RKLIHL------EVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGG 171
K + L K A+ + RE+ +L + +IV + G+ + ++I +EY+ GG
Sbjct: 713 VKQVSLGDFSKTSHKQAMVDALQREMNLLRDFQHDNIVQYLGSSSDEEYLNIFLEYVPGG 772
Query: 172 SLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDF 231
S+ +L K G+ E ++ +LKGL YL ++ I+HRD+K +N+LV++ G +KI DF
Sbjct: 773 SVSSMLTKYGQFEEPLVKHFVRQILKGLDYLHSRN-IIHRDIKGANVLVDNKGNVKISDF 831
Query: 232 GVSGQLIDSMAN--SFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIP 286
G+S ++ S +N S G+ +M+PE ++ T Y++++DIWSLG +VEM G +P P
Sbjct: 832 GISKKIEASSSNRQSLQGSVYWMAPEVVKQTSYTLKADIWSLGCLIVEMLTGSHPFP 888
>UniRef50_Q75CM3 Cluster: ACL104Cp; n=1; Eremothecium gossypii|Rep:
ACL104Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 947
Score = 128 bits (308), Expect = 3e-28
Identities = 68/199 (34%), Positives = 117/199 (58%), Gaps = 6/199 (3%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN-FAHI 148
F++ +G+G GVV K H T + A K+++L+ + + +E++ L +I
Sbjct: 25 FKRTEVIGRGKFGVVYKAYHAKTKQVYAVKVLNLDCPEDEVEDVQKEIQFLASLKQVPNI 84
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+YG++ D ++ + MEY GGSL +L+ G+I E LG I +L L Y+ K +
Sbjct: 85 TRYYGSYLYDTKLWVIMEYCAGGSLRTLLRP-GKIDEKYLGVIVRKLLIALVYIH-KDNV 142
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQL--IDSMANSFVGTRSYMSPE-RLQGTHYSVQ 265
+HRD+K +N+L+ + G +K+CDFGV+ QL + + GT +M+PE ++G +Y+ +
Sbjct: 143 IHRDIKAANVLITNEGHVKLCDFGVAAQLTAANHKRQTMAGTPYWMAPEVIMEGVYYNTK 202
Query: 266 SDIWSLGLSLVEMAIGMYP 284
+DIWSLG++ E+A G P
Sbjct: 203 ADIWSLGITAYEIATGNPP 221
>UniRef50_UPI0000D9E73A Cluster: PREDICTED: serine/threonine kinase
24 (STE20 homolog, yeast) isoform 1; n=3;
Catarrhini|Rep: PREDICTED: serine/threonine kinase 24
(STE20 homolog, yeast) isoform 1 - Macaca mulatta
Length = 370
Score = 127 bits (307), Expect = 4e-28
Identities = 69/176 (39%), Positives = 112/176 (63%), Gaps = 6/176 (3%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
F KL ++G+G+ G V K T ++A K+I LE + I +E+ VL +C+ ++
Sbjct: 36 FTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVT 95
Query: 150 GFYGAFYSDGEISICMEYMDGGS-LDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+YG++ D ++ I MEY+ GGS LDL+ + G + E+ + TI +LKGL YL + I
Sbjct: 96 KYYGSYLKDTKLWIIMEYLGGGSALDLL--EPGPLDETQIATILREILKGLDYLHSEKKI 153
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPERLQGTHY 262
HRD+K +N+L++ +GE+K+ DFGV+GQL D+ N+FVGT +M+PE ++ + Y
Sbjct: 154 -HRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAY 208
>UniRef50_UPI0000D5575B Cluster: PREDICTED: similar to CG10951-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG10951-PA - Tribolium castaneum
Length = 615
Score = 127 bits (307), Expect = 4e-28
Identities = 70/198 (35%), Positives = 116/198 (58%), Gaps = 7/198 (3%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGL-IMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146
+D+EKL +GQG G R + G ++ +++ +++ + KK + E+++L N
Sbjct: 8 EDYEKLKTVGQGAFGTATLYRRLNDGKQVVMKEVFLMDMDNSEKKSALNEVEILSNLNHP 67
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGR---IPESILGTITSAVLKGLSYL 202
+I+ + G+F +G + I MEY DGG+L LI K + E + I S + +SY+
Sbjct: 68 NIIKYLGSFQKEGSLVIIMEYADGGNLAQLINAKKHKNEIFTEKSILNILSQISAAISYM 127
Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL-IDSMANSFVGTRSYMSPERLQGTH 261
+ I+HRD+K +NI +N NG +K+ DFG+S L S A + VGT Y+SPE +G+
Sbjct: 128 HT-NKILHRDLKSANIFLNMNGNVKVGDFGISKMLNTRSQAQTVVGTPYYLSPEMCEGSD 186
Query: 262 YSVQSDIWSLGLSLVEMA 279
Y+ +SDIW++G L E+A
Sbjct: 187 YNEKSDIWAIGCILYELA 204
>UniRef50_Q7QP54 Cluster: GLP_382_9339_8068; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_382_9339_8068 - Giardia lamblia ATCC
50803
Length = 423
Score = 127 bits (307), Expect = 4e-28
Identities = 100/320 (31%), Positives = 159/320 (49%), Gaps = 43/320 (13%)
Query: 90 FEKLGELGQGNGGVVMKVRH-----KSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN 144
++ L +G G G V K ++ K T L A K I+L+ + + E K+L + N
Sbjct: 10 YQLLSVIGVGAAGTVFKGQYTDPVTKQTSLC-ALKAINLDRTTVRLETLQTECKLLAQSN 68
Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLR 203
+IVG+Y +F + + ++ DL+LK A E ++ I +L+ LSY+
Sbjct: 69 HENIVGYYCSFVHQQYLWLVTPILEVNIQDLLLKLAPNGFDEGVISCIMYDILQALSYME 128
Query: 204 DKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID-----SMANSFVGTRSYMSPERLQ 258
+ HRD+K +NIL+NS+G K+ DFGVS L D M N+ VG+ YM+PE +
Sbjct: 129 QNRQV-HRDIKTANILLNSSGTAKLADFGVSAFLCDDSVERKMRNTLVGSPLYMAPEVIS 187
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
+ ++DIWS G+ L+E+A G+ PP++ N P PM
Sbjct: 188 MQGHDCKADIWSFGVCLIELAQGV----PPNS--------------------NLP-PM-- 220
Query: 319 FELLDYIVNEPPPKLPSG-IFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKV 377
E++ I + PPKLP+ F+ +F++ VD C+ KNP ERA L+ ++ K +K
Sbjct: 221 -EVIVNIYQKDPPKLPANKTFTKQFREVVDMCMVKNPRERASATKLLETKFFSK-HGKKT 278
Query: 378 DIAGWVCKTMDLMPSTPNSN 397
I + + LM + N N
Sbjct: 279 TIDNMLIEYKKLMGAPVNGN 298
>UniRef50_A2FCS6 Cluster: STE family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: STE family protein kinase
- Trichomonas vaginalis G3
Length = 461
Score = 127 bits (307), Expect = 4e-28
Identities = 93/316 (29%), Positives = 154/316 (48%), Gaps = 41/316 (12%)
Query: 85 LSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN 144
L ++ L ++G+G VV + G +A K I LE P + + E+
Sbjct: 5 LEKSQYKILNQVGKGVTAVVYVAECLANGRTVALKTIDLETCPIEIENLRHEVAFWSTSQ 64
Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILK---KAGRIPESILGTITSAVLKGLSY 201
++V ++G+F + I MEYM GS I++ K G E+I+ I VL+ L Y
Sbjct: 65 SPNVVKYHGSFVEGSVLYIVMEYMSAGSCYEIMRYSNKKGIQDEAIIAAILHEVLQALCY 124
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN-----SFVGTRSYMSPER 256
D I HRD+K NIL+N +G++KI DFG+S L++ + +GT YM+PE
Sbjct: 125 FHDNRQI-HRDIKAGNILINEHGDVKIGDFGISANLLEGGQRKRARFTVIGTPCYMAPEV 183
Query: 257 LQGTH-YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRP 315
L+ Y+ ++DIWSLG++ +E+AIG P A +F P
Sbjct: 184 LKEEEGYTEKADIWSLGITAIELAIGAAP--------YANLF-----------------P 218
Query: 316 MAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAE 375
+ + ++ + + PP FS F+DF+ CL ++P +R L+ H++ ++A+
Sbjct: 219 LEV--IVKIVNSPPPQLPEDAKFSSAFRDFIKSCLVQSPAKRPTAHQLLEHKFFKQAK-- 274
Query: 376 KVDIAGWVCKTMDLMP 391
DI G K ++ +P
Sbjct: 275 --DIKGLTKKLVESLP 288
>UniRef50_Q9UKE5 Cluster: TRAF2 and NCK-interacting protein kinase;
n=39; Amniota|Rep: TRAF2 and NCK-interacting protein
kinase - Homo sapiens (Human)
Length = 1360
Score = 127 bits (307), Expect = 4e-28
Identities = 94/303 (31%), Positives = 155/303 (51%), Gaps = 47/303 (15%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE-CNFAHI 148
FE + +G G G V K RH TG + A K+ ++V +++I +E+ +L + + +I
Sbjct: 25 FELVELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNI 82
Query: 149 VGFYGAFYS------DGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLS 200
+YGAF D ++ + ME+ GS+ ++K K + E + I +L+GLS
Sbjct: 83 ATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLS 142
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL- 257
+L +H ++HRD+K N+L+ N E+K+ DFGVS QL ++ N+F+GT +M+PE +
Sbjct: 143 HLH-QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIA 201
Query: 258 ----QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
Y +SD+WSLG++ +EMA G P+ D + A+F
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL--CDMHPMRALF---------------- 243
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
I P P+L S +S +F+ F++ CL KN +R + LM H +IR
Sbjct: 244 ----------LIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQP 293
Query: 374 AEK 376
E+
Sbjct: 294 NER 296
>UniRef50_A2ACR7 Cluster: Cyclin-dependent kinase-like 3; n=10;
Eumetazoa|Rep: Cyclin-dependent kinase-like 3 - Mus
musculus (Mouse)
Length = 353
Score = 127 bits (306), Expect = 6e-28
Identities = 86/289 (29%), Positives = 140/289 (48%), Gaps = 11/289 (3%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+E LG++G+G+ G VMK +HK TG I+A K+ + + + ++ K RE+K L + ++V
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKIATREIKFLKQFRHENLV 63
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
F +I + E++D LD + + L +L+ + YL + + I+
Sbjct: 64 NLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNN-II 122
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLI--DSMANSFVGTRSYMSPER-LQGTHYSVQS 266
HRD+KP NILV+ +G K+CDFG + L + +V TR Y +PE L+ T Y
Sbjct: 123 HRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGKPV 182
Query: 267 DIWSLGLSLVEMAIGMYPIPP--PDAKTLAAIF--GGQNEDHSPGQAPNSPRPMAIFELL 322
DIW+LG ++EMA G +P P D L I G H SP + +L
Sbjct: 183 DIWALGCMIIEMATG-HPFLPSSSDLDLLHKIVLKVGNLTPHLHNIFSKSPIFAGV--VL 239
Query: 323 DYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
+ + + + D V CL+ +P ER L+ H++ +
Sbjct: 240 PQVQHPKTARKKYPKLNGLLADIVHACLQIDPAERTSSTDLLRHDYFTR 288
>UniRef50_Q01I65 Cluster: H0315A08.7 protein; n=8; Oryza sativa|Rep:
H0315A08.7 protein - Oryza sativa (Rice)
Length = 709
Score = 127 bits (306), Expect = 6e-28
Identities = 95/303 (31%), Positives = 155/303 (51%), Gaps = 37/303 (12%)
Query: 86 SDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH-LEVKPAIK---KQIIRELKVLH 141
S+ ++K LG G G V + G A K + + P K KQ+ +E+ +L
Sbjct: 301 SESQWKKGKLLGSGTFGQVYLGFNSENGQFCAIKEVQVISDDPHSKERLKQLNQEIDMLR 360
Query: 142 ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201
+ + +IV +YG+ +D +SI +E++ GGS+ +L++ G E ++ T +L GL+Y
Sbjct: 361 QLSHPNIVQYYGSEMTDDALSIYLEFVSGGSIHKLLREYGPFKEPVIRNYTGQILSGLAY 420
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPE-RLQ 258
L ++ + HRD+K +NILV NGE+K+ DFG++ + I S A SF G+ +M+PE +
Sbjct: 421 LHGRNTV-HRDIKGANILVGPNGEVKLADFGMA-KHISSFAEIRSFKGSPYWMAPEVIMN 478
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
G Y + DIWSLG +++EMA P + +AAIF N P + P+S
Sbjct: 479 GRGYHLPVDIWSLGCTIIEMATAKPPWHKYEG--VAAIFKIANSKEIP-EIPDS------ 529
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVD 378
FS+E K F+ CLK++P R LM+H +++ A +
Sbjct: 530 -------------------FSEEGKSFLQMCLKRDPASRFTATQLMDHPFVQDHPAVRAA 570
Query: 379 IAG 381
+G
Sbjct: 571 KSG 573
>UniRef50_Q9VC32 Cluster: CG10951-PA; n=2; Sophophora|Rep:
CG10951-PA - Drosophila melanogaster (Fruit fly)
Length = 841
Score = 127 bits (306), Expect = 6e-28
Identities = 83/277 (29%), Positives = 151/277 (54%), Gaps = 15/277 (5%)
Query: 10 NLTLPPGSIDTNPAATPSNMTPQLKSATANERQGLAGKSKTSI-EALTERLEQIEMDDTQ 68
+L LP G +T + + P + + T G G + TS+ EA++ + +M + Q
Sbjct: 28 SLQLPLGQNTQRKQSTCTRVLPTVFTIT----DGTTGAASTSLAEAMSS--SKAQMPNRQ 81
Query: 69 RRRIEVFLCQKEKIGELSDD--DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHL-EV 125
+++ + ++ +G + ++EK+ +GQG+ G+ + R KS G + K I+L E+
Sbjct: 82 ESLLQLSVPRETGVGVAGPELANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSEL 141
Query: 126 KPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRI- 183
P + + E+ V + + +IV + G+F D + I MEY DGG+L +I ++ G++
Sbjct: 142 SPPGRDLAMNEVDVFSKLHHPNIVSYLGSFIKDNTLLIEMEYADGGTLAQIIAERQGKLH 201
Query: 184 -PESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM- 241
PE + + + ++Y+ ++ I+HRD+K +N+ +N G +KI DFG+S + +
Sbjct: 202 FPERYIIAVFEQISSAINYMHSEN-ILHRDLKTANVFLNRRGIVKIGDFGISKIMNTKIH 260
Query: 242 ANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEM 278
A + +GT Y SPE +G Y +SDIW+LG L EM
Sbjct: 261 AQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEM 297
>UniRef50_Q869T7 Cluster: Similar to Dictyostelium discoideum (Slime
mold). Kinase responsive to stress 1-like kinase; n=2;
Dictyostelium discoideum|Rep: Similar to Dictyostelium
discoideum (Slime mold). Kinase responsive to stress
1-like kinase - Dictyostelium discoideum (Slime mold)
Length = 1176
Score = 127 bits (306), Expect = 6e-28
Identities = 88/288 (30%), Positives = 149/288 (51%), Gaps = 35/288 (12%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
+DF +LG G G V K HK G +A K+I ++ ++ Q E+ +L C +
Sbjct: 392 NDFILDEKLGDGAYGSVYKGTHKDLGFTLAIKVIEMKESESVSLQ--NEINILKNCKSPN 449
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
IV ++G+ ++ I I +++ GS+ D+I + E+ + + LKGL YL ++
Sbjct: 450 IVSYFGSLQTESHIWILLDFCALGSIRDIIESTEKTLNEAQISFVVKNTLKGLIYLHSQN 509
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANS--FVGTRSYMSPERLQGTHYSV 264
I+HRDVK +N+L++ ++KI DFGVS +L ++ S +GT +M+PE + +Y
Sbjct: 510 -IIHRDVKAANVLLSEGCDVKIADFGVSEKLNGALDQSKEMIGTPLWMAPEVILKKNYDY 568
Query: 265 QSDIWSLGLSLVEMAIGMYP-IPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLD 323
++DIWSLG++++EMA G+ P I P + + + PN P
Sbjct: 569 KADIWSLGITIIEMADGLPPHIDLPPMRAMKMV-------------PNWP---------- 605
Query: 324 YIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
PP +S DF+ RCL K+P++RA L+ H +++K
Sbjct: 606 -----PPTFAEPKKWSPLLNDFLARCLVKDPEKRASPIDLLCHPFLKK 648
>UniRef50_Q55FT4 Cluster: Putative uncharacterized protein tsuA;
n=2; Eukaryota|Rep: Putative uncharacterized protein
tsuA - Dictyostelium discoideum AX4
Length = 2247
Score = 127 bits (306), Expect = 6e-28
Identities = 72/211 (34%), Positives = 120/211 (56%), Gaps = 8/211 (3%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR-ELKVLHECNF 145
DDD++ +G++G+G+ G V K R K TG ++A K+I + K +R E+ +L +
Sbjct: 2 DDDYKLIGQIGEGSFGKVYKYRKKFTGQLVACKVISKKGKNEEDILSLRQEIDILKNLSH 61
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
+I+ F F + E ++ EY DG L I+ + + ++ +I ++ L+YL K
Sbjct: 62 PNIIQFISCFENKNEFTLVTEYADG-DLSQIISEEKTLSVDLIQSICYQLVIALNYLHYK 120
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYS 263
I HRD+KP NIL+ S G+IK+CDFG + + + + S GT Y++PE +Q Y
Sbjct: 121 KVI-HRDIKPQNILITSGGQIKVCDFGFAKTISSNSILLTSLKGTPLYLAPEIIQEQPYD 179
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLA 294
++D+WSLG+ L ++ +G PP A +LA
Sbjct: 180 YKADLWSLGIILYQILVGS---PPFSANSLA 207
>UniRef50_O59790 Cluster: Serine/threonine-protein kinase ark1;
n=21; Ascomycota|Rep: Serine/threonine-protein kinase
ark1 - Schizosaccharomyces pombe (Fission yeast)
Length = 355
Score = 127 bits (306), Expect = 6e-28
Identities = 69/197 (35%), Positives = 105/197 (53%), Gaps = 3/197 (1%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE--VKPAIKKQIIRELKVLHECNFAH 147
FE LG+G G V + K TG I+A K +H V+ I+KQ+ RE+++ +
Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
I+ YG F+ + I + +E+ G L L++A R E + + LSYL KH
Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 208
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSD 267
I HRD+KP NIL+ +GEIK+ DFG S + + GT Y+ PE ++G ++ + D
Sbjct: 209 I-HRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVD 267
Query: 268 IWSLGLSLVEMAIGMYP 284
+WSLG+ E +G P
Sbjct: 268 LWSLGVLTYEFLVGAPP 284
Score = 36.3 bits (80), Expect = 1.4
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Query: 332 KLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
K+PS + D +D + R L+ NP++R L+ +M H WI K
Sbjct: 304 KIPSFVPPDA-RDLISRLLQHNPEKRMSLEQVMRHPWIVK 342
>UniRef50_Q5FZP2 Cluster: P21-activated kinase; n=1; Entamoeba
histolytica|Rep: P21-activated kinase - Entamoeba
histolytica
Length = 467
Score = 126 bits (305), Expect = 8e-28
Identities = 85/244 (34%), Positives = 134/244 (54%), Gaps = 22/244 (9%)
Query: 47 KSKTSIEALTERLEQIEMDDTQRRRIEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMK 106
+SK +E L E +E++++ D V + Q + E D FEK+GE G G V
Sbjct: 162 QSKAVVEPLPEDVEKVQLKD-------VTIEQDPR--EFYSD-FEKIGE---GASGEVFS 208
Query: 107 VRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGE--ISIC 164
+ K+ G+++A K +EV +K I E+ ++ C ++V FY AFY + + +
Sbjct: 209 AKRKADGIVVALK--QMEVNNDNEKLIATEISLMKGCKHDNVVTFYEAFYLPAKKLMWMS 266
Query: 165 MEYMDGGSLDLILKKAGRIP--ESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNS 222
MEYMDGG L IL+ I E + + L+ L+++ H I HRD+K N+L+ +
Sbjct: 267 MEYMDGGCLTDILENHDIIEMTEPQIAYVCRETLRALNFIHGLHCI-HRDIKSDNMLLTN 325
Query: 223 NGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAI 280
+G +K+ DFG + QL N + VGT +M+PE ++G Y V+ DIWSLG+ ++EMA
Sbjct: 326 DGHVKLADFGYAAQLNQKQKNRNTVVGTPYWMAPELIRGHDYGVKIDIWSLGIMVMEMAE 385
Query: 281 GMYP 284
G P
Sbjct: 386 GDPP 389
>UniRef50_A0D0Y6 Cluster: Chromosome undetermined scaffold_33, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_33,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 415
Score = 126 bits (305), Expect = 8e-28
Identities = 73/214 (34%), Positives = 118/214 (55%), Gaps = 6/214 (2%)
Query: 75 FLCQKEKIGELSDDDFEKL--GELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIK-K 131
F C+ E + + ++ DFE + G LG+G+ G V R + TGL+ A K+++ K I +
Sbjct: 40 FECKAE-LPKRNESDFEIVNQGYLGKGSFGCVKLARDRQTGLLYAMKIVNQIEKSDISIE 98
Query: 132 QIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTI 191
+ RE+++ + H++ + F + I + +EY + GSL L+K +PE+
Sbjct: 99 NLRREIRIQKKLQHPHVIQLFEFFEDEQNIYLVLEYAENGSLFGYLRKRKILPENEAFVY 158
Query: 192 TSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQ-LIDSMANSFVGTRS 250
G+ YL K I+HRD+KP N+L++ +G IKICDFG S + +I N+F GT
Sbjct: 159 FFQTCLGIDYLHKKQ-IIHRDLKPENLLLDKDGNIKICDFGWSAEMMITQTRNTFCGTID 217
Query: 251 YMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284
YM+PE L+ + D+W LG+ L E+ G P
Sbjct: 218 YMTPEMLEDKPHDQTLDMWCLGVLLYELIHGQAP 251
>UniRef50_Q9Y4K4 Cluster: Mitogen-activated protein kinase kinase
kinase kinase 5; n=35; Euteleostomi|Rep:
Mitogen-activated protein kinase kinase kinase kinase 5
- Homo sapiens (Human)
Length = 846
Score = 126 bits (305), Expect = 8e-28
Identities = 80/254 (31%), Positives = 137/254 (53%), Gaps = 12/254 (4%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR-ELKVLHECNFAH 147
D+E + +G G G V K R+ TG + A K+I LE P +I+ E+ ++ EC +
Sbjct: 19 DYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLE--PGDDFSLIQQEIFMVKECKHCN 76
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
IV ++G++ S ++ ICMEY GGSL I G + E + + L+GL+YL K
Sbjct: 77 IVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTK-G 135
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL---QGTHY 262
MHRD+K +NIL+ +G++K+ DFGV+ ++ ++A SF+GT +M+PE + Y
Sbjct: 136 KMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGY 195
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIF-EL 321
+ DIW++G++ +E +G P D + A+F + P + + + + F
Sbjct: 196 NQLCDIWAVGITAIE--LGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNF 253
Query: 322 LDYIVNEPPPKLPS 335
+ + + P K P+
Sbjct: 254 VKIALTKNPKKRPT 267
>UniRef50_Q5MAI5 Cluster: Cyclin-dependent kinase-like 4; n=18;
Mammalia|Rep: Cyclin-dependent kinase-like 4 - Homo
sapiens (Human)
Length = 315
Score = 126 bits (305), Expect = 8e-28
Identities = 89/294 (30%), Positives = 148/294 (50%), Gaps = 23/294 (7%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMA-RKLIHLEVKPAIKKQIIRELKVLHECNFA 146
+ +EKL + G+G+ GVV K R+K++G ++A +K + E P +KK +RE+++L +
Sbjct: 2 EKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHP 61
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
++V F ++ + EY D L+ + + + + ++ ++ L+ L++ H
Sbjct: 62 NLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHI-H 120
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA-NSFVGTRSYMSPERLQG-THYSV 264
+HRD+KP NIL+ G IKICDFG + LI A +V TR Y +PE L G T Y
Sbjct: 121 NCIHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAPELLVGDTQYGS 180
Query: 265 QSDIWSLGLSLVEMAIGMYPIPP--PDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322
DIW++G E+ G P+ P D L I + G+ PR +IF+
Sbjct: 181 SVDIWAIGCVFAELLTGQ-PLWPGKSDVDQLYLII------RTLGKL--IPRHQSIFKSN 231
Query: 323 DYI--VNEPPPKLPSGI---FSDEFK---DFVDRCLKKNPDERADLKTLMNHEW 368
+ ++ P P+ + FSD +F+ CLK NPD+R L+ +
Sbjct: 232 GFFHGISIPEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSY 285
>UniRef50_UPI00006CBCB4 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 671
Score = 126 bits (304), Expect = 1e-27
Identities = 85/252 (33%), Positives = 132/252 (52%), Gaps = 13/252 (5%)
Query: 48 SKTSIEALTERLEQIEMD-DTQRRRIEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMK 106
SK + + EQ++++ D Q+ +I++ I + +DF+ L ELG G+ V
Sbjct: 381 SKADLINQQAQSEQLKINNDEQKFKIQI------SIFPVDLNDFKFLKELGHGSYATVRS 434
Query: 107 VRHKSTGLIMARKLIHLE--VKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISIC 164
HK T ++A K + + P K+ + RE+K+L N +I+ Y + I++
Sbjct: 435 ALHKKTNFVVAVKSYNKSKLLDPQKKQNLDREIKILQNLNHKYIIKLYKVIENSQSINLV 494
Query: 165 MEYMDGGSLDLILK-KAG-RIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNS 222
MEY L + LK K+G R+ E I +L+ + YL K I HRD+K NIL+NS
Sbjct: 495 MEYSSSIPLSVYLKQKSGKRLHELEAKVIFRQILEAVLYLHKKRVI-HRDIKLENILINS 553
Query: 223 NGEIKICDFGVSGQLIDSMA-NSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIG 281
N +IK+ DFG S Q+ S F GT +YM+PE + YS + DIW+LG+ L ++ G
Sbjct: 554 NRKIKLIDFGFSIQVQPSCKLTMFCGTPNYMAPEIINKKGYSFEVDIWALGILLYKLLTG 613
Query: 282 MYPIPPPDAKTL 293
YP + K L
Sbjct: 614 YYPFAGKENKQL 625
>UniRef50_UPI000069E043 Cluster: UPI000069E043 related cluster; n=3;
Xenopus tropicalis|Rep: UPI000069E043 UniRef100 entry -
Xenopus tropicalis
Length = 1168
Score = 126 bits (304), Expect = 1e-27
Identities = 85/291 (29%), Positives = 151/291 (51%), Gaps = 37/291 (12%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146
+ +E L ELG G G V K +++ A K++ + + A++ + E+ +L +C
Sbjct: 30 EQHWEILSELGDGAFGKVYKAQNRGNRNFAAVKVLDIPSEEALEDHVA-EINILGQCQHP 88
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDK 205
+I+ A Y + ++ I +E+ GG+LD I+ + GR + ES + + L L YL +
Sbjct: 89 NILALLEATYWEKKLWILLEFCAGGALDGIMLELGRGLTESQISVVCFQTLLALQYLHN- 147
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSP-----ERLQ 258
H I+HRD+K NIL+ G+I++ DFGVS ++ +SF+GT +M+P E +
Sbjct: 148 HKIIHRDLKAGNILLTQQGDIRLADFGVSAVNTQTLQRRSSFIGTPYWMAPEVVMCETCK 207
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAI 318
Y ++D+WSLG++L+E+A PP N D +P +
Sbjct: 208 DAPYDSKADVWSLGVTLIELA----EREPP------------NHDLNPTRV--------- 242
Query: 319 FELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
LL I ++PP ++S F +F+++CL+++P ER + L+ H ++
Sbjct: 243 --LLKIIKSQPPCLKYKRLWSQNFNNFLEKCLQRSPQERLSVSQLLQHSFV 291
>UniRef50_Q556S2 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum AX4
Length = 513
Score = 126 bits (304), Expect = 1e-27
Identities = 89/291 (30%), Positives = 148/291 (50%), Gaps = 31/291 (10%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146
+ FE +LG+G+ G V + HKS+ +A K + ++ I +E+++L +CN
Sbjct: 39 ETSFEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEANDVEP-ISKEIQILKKCNNP 97
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDK 205
++V ++G+ + I M+Y S + I++ G+ E + I L GL YL K
Sbjct: 98 YVVSYFGSIMLKNKYWILMDYCSLSSFNDIMQSIGKTFKEKEISLILQQSLLGLVYLHSK 157
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA-NSFVGTRSYMSPERLQGTHYSV 264
I+HRD+K +NIL++ G++KI DFGVS Q+ + + S GT +M+PE L T Y+
Sbjct: 158 Q-IIHRDIKSANILLDETGQVKIADFGVSQQIQSTFSKGSIAGTPYWMAPEILNQTDYNN 216
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDY 324
+ D+WSLG+ +E+A G P+ + + G RP F
Sbjct: 217 KIDVWSLGIVAIELADGEPPLSEVNPMRAMYMIG--------------RRPPPTF----- 257
Query: 325 IVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAE 375
+ P K +S EF FVD+CL K+ +ER L++H +I+ A+ +
Sbjct: 258 ---KDPKK-----WSPEFVSFVDKCLTKDINERWSPSQLLDHPFIKSAKPD 300
>UniRef50_A5DCL7 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 725
Score = 126 bits (304), Expect = 1e-27
Identities = 68/205 (33%), Positives = 122/205 (59%), Gaps = 6/205 (2%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN-FAHI 148
+++ +G+G GVV K HK+T ++A K+++L+ +P ++ +E++ L E ++
Sbjct: 2 YKRTDVIGRGKFGVVYKGYHKTTKHVVAIKVLNLDTEPEEVAEVQQEIQFLSEIKQVPNV 61
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+YG+F D ++ I M+Y GG + +LK G E +G + +L L + K +
Sbjct: 62 THYYGSFLVDTKLWIIMDYCAGGLIRTLLK-LGVFEEQYIGVVLRELLVALQAVH-KLGV 119
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQ--LIDSMANSFVGTRSYMSPERL-QGTHYSVQ 265
+HRD+K +N+L+ + G +++CDFGV+ + L S + GT +M+PE + +G Y+V+
Sbjct: 120 IHRDLKSANVLITNEGNVQLCDFGVAARISLTASKRTTMAGTPYWMAPEVIREGDTYNVK 179
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDA 290
+DIWSLG++L E+A G P DA
Sbjct: 180 ADIWSLGITLYELATGNPPYCDKDA 204
>UniRef50_Q6CVA2 Cluster: Serine/threonine-protein kinase STE20;
n=1; Kluyveromyces lactis|Rep: Serine/threonine-protein
kinase STE20 - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 989
Score = 126 bits (304), Expect = 1e-27
Identities = 90/289 (31%), Positives = 151/289 (52%), Gaps = 14/289 (4%)
Query: 3 KMSKNKLNLTLPPGSIDTNPA-ATPSNMTPQLKSATANERQGLAG--KSKTSIEALTERL 59
K ++ NL LP + T P A P+ TP+ S A GLA K +++ + R
Sbjct: 610 KAAEKPANL-LPARAAPTPPKPAIPT--TPEQSSIPAIP-SGLAVEVKEESNTSNVQTRK 665
Query: 60 EQIEMDDTQRRRIEVFLCQKEKIGELSDDD--FEKLGELGQGNGGVVMKVRHKSTGLIMA 117
Q + + ++R+ + + +I D ++ L ++GQG G V T +A
Sbjct: 666 AQEKKREERKRKNQQIQSKLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVA 725
Query: 118 RKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLIL 177
K ++LE +P K+ I+ E+ V+ +IV F ++ G++ + MEYM+GGSL ++
Sbjct: 726 IKQMNLEKQPK-KELIVNEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVV 784
Query: 178 KKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL 237
+ E +G ++ LKGL +L K ++HRD+K NIL++ NG+IK+ DFG Q+
Sbjct: 785 THC-ILTEGQIGAVSRETLKGLQFLHSK-GVIHRDIKSDNILLSMNGDIKLTDFGFCAQI 842
Query: 238 --IDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284
++ + VGT +M+PE + Y + DIWSLG+ ++EM G P
Sbjct: 843 NEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPP 891
>UniRef50_Q54XL6 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 574
Score = 125 bits (302), Expect = 2e-27
Identities = 92/316 (29%), Positives = 160/316 (50%), Gaps = 40/316 (12%)
Query: 71 RIEVFLCQKEKIGELSD-----DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE- 124
R E + + ++I +SD + + + +G+G G V K +A K++ L+
Sbjct: 73 RRESIIRELQQIKTISDYPSQANQYNLIEPIGEGTEGRVFKAYCIPLKENVAIKVVELDK 132
Query: 125 VKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSL-DLI-LKKAGR 182
+ P K +I+E+KV++ N +++ ++ +F + ++ + M+Y+ GGSL D++ K
Sbjct: 133 MDPQFVKDVIKEVKVMNGNNHPNLIHYHTSFLENNQLWLVMDYLGGGSLADIMKFKYPDG 192
Query: 183 IPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA 242
IPE + T+ ++LKGL YL H +HRD+K NIL+ +G I++ DFGVS +
Sbjct: 193 IPEVLAVTVLKSLLKGLEYLH-SHQRIHRDLKSDNILIGEDGAIELADFGVSAMFEKNTC 251
Query: 243 ---NSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP--IPPPDAKTLAAIF 297
+ VGT +M+PE + Y+ DIWS G++ +E+ G P PP + +F
Sbjct: 252 CSRKTIVGTPCWMAPEIISERGYNQGVDIWSFGITAIELIRGKPPGYDLPPSKVFMNLLF 311
Query: 298 GGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDER 357
G NSP + E K G+ S +KD VD+CL+K P +R
Sbjct: 312 G------------NSPS-----------LQEEEDK---GVCSHLYKDLVDKCLQKEPSKR 345
Query: 358 ADLKTLMNHEWIRKAE 373
+ L+ H+ ++A+
Sbjct: 346 PNASKLLEHKVFKQAK 361
>UniRef50_Q4DSQ1 Cluster: Protein kinase, putative; n=2; Trypanosoma
cruzi|Rep: Protein kinase, putative - Trypanosoma cruzi
Length = 547
Score = 125 bits (302), Expect = 2e-27
Identities = 91/277 (32%), Positives = 136/277 (49%), Gaps = 26/277 (9%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIK--KQIIRELKVLHECNFAHIVGFYG 153
+G+G+ GVV + + T I+A K I K K + +EL +L + HIV G
Sbjct: 221 IGKGSFGVVFQAMDRDTNHIIAVKEISFSEGSESKALKAVRKELALLKLLDHPHIVKCLG 280
Query: 154 AFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDV 213
+ + I MEY+ GGS+ +L+ G E T +L+GL YL K+ IMHRD+
Sbjct: 281 EECEESCLRIYMEYVSGGSISSVLRTFGPFHEKQASIYTRQMLEGLEYLHSKN-IMHRDL 339
Query: 214 KPSNILVNSNGEIKICDFGVSGQLIDSMAN-SFVGTRSYMSPERLQGTHYSVQSDIWSLG 272
K N+LV+ NG +KI DFG + L+D A+ + GT +M+PE + + SD+WS+G
Sbjct: 340 KGDNLLVDPNGTLKISDFGTAKDLLDPTASTALAGTAYFMAPEVILSQGVGLPSDVWSVG 399
Query: 273 LSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPK 332
++EM G PP F G +S M + E + E PK
Sbjct: 400 CCVIEMLTGS---PP---------FSGVKNQYS--------MMMRVAETEGELFPEMIPK 439
Query: 333 LPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
S K F+ RCL+++P +RA K L++ WI
Sbjct: 440 --GHRLSSGAKSFLRRCLQRDPLKRATAKELLDDPWI 474
>UniRef50_A0BYR7 Cluster: Chromosome undetermined scaffold_137,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_137,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 681
Score = 125 bits (302), Expect = 2e-27
Identities = 71/207 (34%), Positives = 110/207 (53%), Gaps = 4/207 (1%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLI-HLEVKPA-IKKQIIRELKVLH 141
E DFE + LGQG G V KVRHK T ++ A K I ++K + +QII E+K+++
Sbjct: 28 EACTQDFEVIQGLGQGAFGKVFKVRHKKTKMVFALKQIAKKQIKQQKMTQQIINEVKIMY 87
Query: 142 ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201
+IV Y + + I + +E GG L L + GR E + + + Y
Sbjct: 88 GLEHPNIVKLYNHYEEEDYIYLILECATGGQLWQKLNRVGRFDEKTVKQFMQEAMSAIEY 147
Query: 202 LRDKHA-IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGT 260
L ++ I+HRD+KP NIL+++NG IKI DFG S + + ++ GT Y++PE +
Sbjct: 148 LHTRNPPIIHRDIKPENILLDANGHIKIADFGWS-NINNHQRTTYCGTLDYLAPEMILEC 206
Query: 261 HYSVQSDIWSLGLSLVEMAIGMYPIPP 287
+ + D WSLG+ + E+ G P P
Sbjct: 207 GHDEKIDNWSLGVLIYELLTGKAPFAP 233
>UniRef50_Q751V1 Cluster: AFR724Cp; n=1; Eremothecium gossypii|Rep:
AFR724Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 440
Score = 125 bits (302), Expect = 2e-27
Identities = 80/213 (37%), Positives = 120/213 (56%), Gaps = 7/213 (3%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+E L +G+GN G V K R ++ I+A K+++LE + +E+ L E +I
Sbjct: 20 YEILQCIGRGNFGDVYKARDLTSNEIVAIKVVNLEDTDEPIDLLAQEIFFLSELRSPYIT 79
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLSYLRDKHA 207
+ AF D + I MEY GGS +LK ++ E I S VL GL YL +
Sbjct: 80 NYKTAFLVDVSMWIVMEYCGGGSCAELLKYTPEHKVTEEQCAFIVSEVLIGLDYLHSQRK 139
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQ-LIDSMANSFVGTRSYMSPERLQGTH--YSV 264
I HRD+K +NIL+ NG +K+ DFGVSGQ ++ ++FVGT +M+PE + Y+
Sbjct: 140 I-HRDIKSANILLTDNGHVKLGDFGVSGQMMVTRKRDTFVGTPFWMAPEVIDRNKQGYNE 198
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDA-KTLAAI 296
+DIWSLG++++E+ +G P+ DA K L AI
Sbjct: 199 MADIWSLGITVIELLMGHPPLDKYDAMKALMAI 231
Score = 37.1 bits (82), Expect = 0.82
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
Query: 325 IVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
I PPKL FS +DFV +CL K+P +R L+ H ++++
Sbjct: 231 IPKRDPPKLDKR-FSSHARDFVAQCLIKDPSQRPTAAELLKHRFVKR 276
>UniRef50_Q4P5N0 Cluster: Serine/threonine-protein kinase SMU1; n=1;
Ustilago maydis|Rep: Serine/threonine-protein kinase
SMU1 - Ustilago maydis (Smut fungus)
Length = 746
Score = 125 bits (302), Expect = 2e-27
Identities = 70/197 (35%), Positives = 112/197 (56%), Gaps = 5/197 (2%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+ L ++GQG G V T + +A K ++LE +P K II E+ V+ E +IV
Sbjct: 472 YRSLQKIGQGASGGVFTAYQVGTNVSVAIKQMNLEQQPK-KDLIINEILVMKESRHRNIV 530
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
F +F G++ + MEYM+GGSL ++ + E + ++ VL+GL +L +H ++
Sbjct: 531 NFIDSFLFKGDLWVVMEYMEGGSLTDVVT-CNIMTEGQIAAVSREVLEGLRHLH-QHGVI 588
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQSD 267
HRD+K N+L++ G+IK+ DFG Q+ +S A + VGT +M+PE + Y + D
Sbjct: 589 HRDIKSDNVLLSLQGDIKLTDFGFCAQIGESQAKRTTMVGTPYWMAPEVVTRKEYGPKVD 648
Query: 268 IWSLGLSLVEMAIGMYP 284
IWSLG+ +EM G P
Sbjct: 649 IWSLGIMCIEMVEGEPP 665
>UniRef50_Q00532 Cluster: Cyclin-dependent kinase-like 1; n=24;
Bilateria|Rep: Cyclin-dependent kinase-like 1 - Homo
sapiens (Human)
Length = 357
Score = 125 bits (302), Expect = 2e-27
Identities = 70/204 (34%), Positives = 113/204 (55%), Gaps = 6/204 (2%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMA-RKLIHLEVKPAIKKQIIRELKVLHECNFA 146
+ +EK+G++G+G+ GVV K R++ TG I+A +K + E P IKK +RE+++L +
Sbjct: 2 EKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHP 61
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
++V F + + EY D L + + +PE ++ +IT L+ +++ KH
Sbjct: 62 NLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCH-KH 120
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLI--DSMANSFVGTRSYMSPERLQG-THYS 263
+HRDVKP NIL+ + IK+CDFG + L +V TR Y SPE L G T Y
Sbjct: 121 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 180
Query: 264 VQSDIWSLGLSLVEMAIGMYPIPP 287
D+W++G E+ G+ P+ P
Sbjct: 181 PPVDVWAIGCVFAELLSGV-PLWP 203
>UniRef50_A7NWI3 Cluster: Chromosome chr5 scaffold_2, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr5 scaffold_2, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 696
Score = 125 bits (301), Expect = 2e-27
Identities = 80/225 (35%), Positives = 124/225 (55%), Gaps = 13/225 (5%)
Query: 94 GEL-GQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQI---IREL----KVLHECNF 145
GEL G G G V + +G ++A K + + A K++ IREL K+L +
Sbjct: 70 GELIGCGAFGRVYMGMNLDSGELLAIKQVSIAANSASKEKTQAHIRELEEEVKLLKNLSH 129
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
+IV + G D ++I +E++ GGS+ +L K G PES++ T +L GL YL K
Sbjct: 130 PNIVRYLGTAREDESLNILLEFVPGGSISSLLGKFGSFPESVIRMYTKQLLLGLEYLH-K 188
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID----SMANSFVGTRSYMSPERLQGTH 261
+ IMHRD+K +NILV++ G IK+ DFG S ++++ + A S GT +M+PE + T
Sbjct: 189 NGIMHRDIKGANILVDNKGCIKLADFGASKKVVELATMTGAKSMKGTPYWMAPEVILQTG 248
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSP 306
+S +DIWS+G +++EMA G P + A G + H P
Sbjct: 249 HSFSADIWSVGCTVIEMATGKPPWSQQYQEVAALFHIGTTKSHPP 293
>UniRef50_Q57WI0 Cluster: Protein kinase, putative; n=1; Trypanosoma
brucei|Rep: Protein kinase, putative - Trypanosoma
brucei
Length = 439
Score = 125 bits (301), Expect = 2e-27
Identities = 86/284 (30%), Positives = 139/284 (48%), Gaps = 32/284 (11%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHL--EVKPAIKKQIIRELKVLHECNFAHIVGFYG 153
+G+G+ GVV + ++ T I+A K I + + REL L + HIV F G
Sbjct: 50 IGKGSFGVVFQAMNRDTNQIIAVKEIAFTSNADSQLLDTVRRELTTLKLLDHPHIVKFLG 109
Query: 154 AFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDV 213
++D + I +EY+ GGS+ +L+ G E T +L+GL+YL K+ I+HRD+
Sbjct: 110 GEWADNCLRIYLEYVSGGSISSVLRTFGPFQEKQASRFTRQMLEGLAYLHSKN-IIHRDL 168
Query: 214 KPSNILVNSNGEIKICDFGVSGQLIDSMANSF-------VGTRSYMSPERLQGTHYSVQS 266
K N+LV+ NG +KI DFG + L+++ GT +M+PE + G + S
Sbjct: 169 KGDNLLVDPNGTLKISDFGTAKSLVENQPPQHNGVPPTPAGTAYFMAPEAIVGDPVGLSS 228
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
DIWS+G ++EM G P F +S + + E +V
Sbjct: 229 DIWSVGCCVIEMLTGSAP------------FSHMKNQYS--------TMLCVAEHKGELV 268
Query: 327 NEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370
+ PK FS + DF+ RCL+++P++R+ L+ WI+
Sbjct: 269 SSMIPK--GNNFSSKTLDFLMRCLQRDPEKRSTALELLEDPWIQ 310
>UniRef50_Q54WX4 Cluster: Putative uncharacterized protein aurB;
n=1; Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein aurB - Dictyostelium discoideum
AX4
Length = 384
Score = 125 bits (301), Expect = 2e-27
Identities = 68/208 (32%), Positives = 104/208 (50%), Gaps = 3/208 (1%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPA--IKKQIIRELKVLHECNF 145
DDF+ LG G G V R K + I+A K++ I+ Q+ RE+++
Sbjct: 108 DDFDIGKLLGMGRFGHVYLAREKKSQFIVALKVLFKNQLQTHNIEHQLRREIEIQSHLRH 167
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
+I+ +G FY D + + +E+ GG L+K G E T T + L Y K
Sbjct: 168 PNILRLFGYFYDDKRVFLIIEFAKGGECFKELQKVGSFNEQTAATYTLQIADALRYCHSK 227
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQ 265
H I HRD+KP N+L+ GEIKI DFG S ++ ++F GT Y+ PE ++ Y
Sbjct: 228 HVI-HRDIKPENLLIGVGGEIKIADFGWSVHAPNTKRSTFCGTLEYLPPEVIEKKGYDQT 286
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDAKTL 293
+D+WSLG+ + E +G P + K +
Sbjct: 287 ADVWSLGILIFEFLVGRSPFTSDEEKNI 314
Score = 39.1 bits (87), Expect = 0.20
Identities = 18/38 (47%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Query: 334 PSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
PS I S E KD + R L +P +R LK ++NH WI+K
Sbjct: 326 PSSI-SPEAKDLISRLLVSDPHQRITLKDVINHPWIKK 362
>UniRef50_Q54R82 Cluster: Protein serine/threonine kinase; n=2;
Dictyostelium discoideum|Rep: Protein serine/threonine
kinase - Dictyostelium discoideum AX4
Length = 1267
Score = 125 bits (301), Expect = 2e-27
Identities = 95/312 (30%), Positives = 153/312 (49%), Gaps = 38/312 (12%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARK---LIHLEVKPAIKKQII---RELKVLHECNFAHIV 149
LG+G G V +K TG + A K ++ + P +K I+ +E++V+ +IV
Sbjct: 501 LGRGGYGSVYLGLNKDTGELFAVKQLEIVDINSDPKLKNMILSFSKEIEVMRSLRHDNIV 560
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209
+ G +S+ +EY+ GGS+ +L K G E+++ T +L+GLS+L ++I+
Sbjct: 561 RYLGTSLDQSFLSVFLEYIPGGSISSLLGKFGAFSENVIKVYTKQILQGLSFLH-ANSII 619
Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQL--IDSMANSFVGTRSYMSPERLQGTHYSVQSD 267
HRD+K +NIL+++ G +K+ DFG S I S S GT +M+PE ++ T + SD
Sbjct: 620 HRDIKGANILIDTKGIVKLSDFGCSKSFSGIVSQFKSMQGTPYWMAPEVIKQTGHGRSSD 679
Query: 268 IWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVN 327
IWSLG +VEMA P P + LAA+ S PN P M
Sbjct: 680 IWSLGCVIVEMATAQ-P-PWSNITELAAV---MYHIASSNSIPNIPSHM----------- 723
Query: 328 EPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGWVCKTM 387
S E DF++ C K++P ER D L+ H +I + + + + + T
Sbjct: 724 -----------SQEAFDFLNLCFKRDPKERPDANQLLKHPFIMNLD-DNIQLP-TISPTT 770
Query: 388 DLMPSTPNSNVS 399
L +T N+ +
Sbjct: 771 TLSTNTTNTTAT 782
>UniRef50_UPI0000F1EE77 Cluster: PREDICTED: similar to
serine/threoine kinase; n=5; Danio rerio|Rep: PREDICTED:
similar to serine/threoine kinase - Danio rerio
Length = 1277
Score = 124 bits (300), Expect = 3e-27
Identities = 91/286 (31%), Positives = 151/286 (52%), Gaps = 39/286 (13%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+E LGELG G G V K ++++TG++ A K+I + + + I E+ +L C +I+
Sbjct: 34 WETLGELGDGAFGKVYKAQNQTTGVLGAVKVIEVRSEEQLD-DYITEIDILAACRHPNIL 92
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKHAI 208
A + +G + I +EY GG+LD I+ + R + E + + L+ L YL H I
Sbjct: 93 SLLDAIFFEGWLWILLEYCPGGALDDIMLELERGLTEQQISEVCWQTLQALFYLHQHH-I 151
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPERL-----QGTH 261
+HRD+K NIL+ +G++K+ DFGVS + ++ ++F+GT +M+PE + +
Sbjct: 152 IHRDLKAGNILLTMDGQVKLADFGVSAKNDYTLQKRSTFIGTPYWMAPEVIMCETSKDNP 211
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
Y+ ++DIWS+G++L+E A + PP +S PM +
Sbjct: 212 YTSKADIWSMGITLIEAA----EMEPPH---------------------HSLNPMRV--- 243
Query: 322 LDYIVNEPPPKLPS-GIFSDEFKDFVDRCLKKNPDERADLKTLMNH 366
L I PPP L + +S F+DF+ R L+KNP+ R + LM H
Sbjct: 244 LLKITKSPPPTLSNPRQWSSHFQDFLRRSLQKNPEARWGTQQLMAH 289
>UniRef50_UPI0000499EFD Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 978
Score = 124 bits (300), Expect = 3e-27
Identities = 92/286 (32%), Positives = 143/286 (50%), Gaps = 36/286 (12%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
D+F L +GQG+ G V K H++T I+A K + K A + I RE+ L +
Sbjct: 10 DEFGFLERIGQGSFGQVYKAFHQNTRTIVAIKRLP---KDADFQDIRREIDTLKVLRSPY 66
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKH 206
I+ +Y + E I MEY GS+ ++ G + E ++ I L+GL YL + H
Sbjct: 67 IIRYYTSVLRQEEFWIVMEYCCYGSVADMMDILGEELKEDVIAQICHDALQGLKYLHELH 126
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTHYSV 264
I HRD+KP+N L+ +G++K+ DFG++ L D + + +GT +++PE + T Y+
Sbjct: 127 KI-HRDIKPANFLITKDGDVKLGDFGIATTLNDKTRHHKTLIGTPHFLAPEIVDETGYNE 185
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDY 324
+ DIW+LG+S++EMA YP P D PM + L
Sbjct: 186 KVDIWALGISIIEMA-ETYP-PYYDMP-----------------------PMRVLML--- 217
Query: 325 IVNEPPPKLPS-GIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
I PPPKL + S ++F+ CL K P R TL+ H++I
Sbjct: 218 IAQNPPPKLKNESEHSYNLQEFLSNCLVKTPQVRPSAYTLLKHDFI 263
>UniRef50_A7PSB1 Cluster: Chromosome chr14 scaffold_27, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr14 scaffold_27, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 670
Score = 124 bits (300), Expect = 3e-27
Identities = 93/288 (32%), Positives = 148/288 (51%), Gaps = 40/288 (13%)
Query: 94 GEL-GQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQI---IREL----KVLHECNF 145
GEL G G G V + +G ++A K + + A K++ IREL K+L +
Sbjct: 64 GELIGCGAFGRVYMGMNLDSGELIAVKQVLITTSNATKEKAQAHIRELEEEVKLLKNLSH 123
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDK 205
+IV + G + ++I +E++ GGS+ +L K G PE+++ T +L GL YL +
Sbjct: 124 PNIVRYLGIVREEETLNILLEFVPGGSISSLLGKFGSFPEAVIRMYTKQLLLGLDYLHN- 182
Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID----SMANSFVGTRSYMSPERLQGTH 261
+ IMHRD+K +NILV++ G IK+ DFG S Q+++ S A S GT +M+PE + T
Sbjct: 183 NGIMHRDIKGANILVDNKGCIKLADFGASKQVVELATISGAKSMKGTPYWMAPEVILQTG 242
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
+S +DIWS+G +++EMA G P + A + G + H P
Sbjct: 243 HSFSADIWSVGCTVIEMATGKPPWSQKYQEVAALFYIGTTKSHPP--------------- 287
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
+P+ + S E KDF+ +CL+K PD R L+ H ++
Sbjct: 288 -----------IPAHL-SAEAKDFLLKCLQKEPDLRPAAYELLKHPFV 323
>UniRef50_Q9W179 Cluster: CG4527-PB, isoform B; n=9; Diptera|Rep:
CG4527-PB, isoform B - Drosophila melanogaster (Fruit
fly)
Length = 1703
Score = 124 bits (300), Expect = 3e-27
Identities = 89/290 (30%), Positives = 147/290 (50%), Gaps = 37/290 (12%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+E +GELG G G V K +HK A K+ LE + + ++ E+ +L E +IV
Sbjct: 37 WEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMV-EIDILSEIKHPNIV 95
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKHAI 208
Y AF D ++ + +EY DGG+LD I+ + + + E + + + +GL++L ++ +
Sbjct: 96 ELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLH-RNKV 154
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSP-----ERLQGTH 261
+HRD+K N+L+ G +K+ DFGVS + +M ++F+GT +M+P E +
Sbjct: 155 IHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNP 214
Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321
Y + DIWSLG++L+E+A + PP N + SP + L
Sbjct: 215 YDHKVDIWSLGITLIELA----QMEPP------------NSEMSPMRV-----------L 247
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
L +EPP +S EF DF+ + L K+P R LM H +I +
Sbjct: 248 LKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAFINR 297
>UniRef50_Q6FJ06 Cluster: Candida glabrata strain CBS138 chromosome
M complete sequence; n=1; Candida glabrata|Rep: Candida
glabrata strain CBS138 chromosome M complete sequence -
Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 867
Score = 124 bits (300), Expect = 3e-27
Identities = 93/305 (30%), Positives = 152/305 (49%), Gaps = 35/305 (11%)
Query: 70 RRIEVFLCQKEKIGE--LSDDDFEKLGELGQG-NGGVVMKVRHKSTGLIMARKLIHLEVK 126
+R++V L + KI +D FE ++GQG +GGV + +A K ++LE +
Sbjct: 544 KRMQVVLSRLSKICTPGTPEDKFETYLKIGQGASGGVYLSHSRSDKSQCVAIKQMNLEKQ 603
Query: 127 PAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPES 186
P K+ I+ E+ V+ +IV + ++ S ++ + MEYM+GG L ++ + E
Sbjct: 604 PK-KELIVNEIMVMSSSKHQNIVNYIDSYLSGLDLWVVMEYMEGGCLTDVVTYCV-LTEG 661
Query: 187 ILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--S 244
+G + VL+GL +L K ++HRD+K N+L++ NG+IK+ DFG Q+ D++ +
Sbjct: 662 QIGAVCREVLQGLEFLHSK-GVLHRDIKSDNVLLSMNGDIKLTDFGFCAQVNDTVIKRTT 720
Query: 245 FVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDH 304
VGT +M+PE + Y + DIWSLG+ M I M PP NE
Sbjct: 721 MVGTPYWMAPEIVSRKEYGPKVDIWSLGI----MIIEMIEGEPPYL----------NET- 765
Query: 305 SPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLM 364
P+ L+ N P S +FK+F+D+CL ERA+ L+
Sbjct: 766 ----------PLRALYLI--ATNGRPEVQEPDRLSKDFKEFIDKCLAVTVSERAESSELL 813
Query: 365 NHEWI 369
H++I
Sbjct: 814 QHKFI 818
>UniRef50_UPI00004999DA Cluster: protein kinase; n=2; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 422
Score = 124 bits (299), Expect = 4e-27
Identities = 69/202 (34%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146
D+ +E L ++G+G G V + K G +A K + + K K+ I+ E+ +L++
Sbjct: 128 DEIYENLEKIGEGGVGDVFRATRKVDGCEVALKRMRITKKS--KRAIVTEVTILNQYRHE 185
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIP--ESILGTITSAVLKGLSYLRD 204
++V + + + + + MEYMDGG L I+ + +P E + I + LK L+YL
Sbjct: 186 NVVTYIECYLINEMLWLVMEYMDGGCLTDIIDRHKEVPLTEHFISFICTETLKALTYLHS 245
Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTHY 262
H + HRD+K N+L+ +G IK+ DFG + QL +N S VGT +M+PE ++ Y
Sbjct: 246 FHCV-HRDIKSDNLLLKKDGSIKLSDFGYAAQLTKQKSNRTSIVGTPYWMAPELIRSQRY 304
Query: 263 SVQSDIWSLGLSLVEMAIGMYP 284
+ DIWSLG+ +EMA G P
Sbjct: 305 DEKVDIWSLGIMCMEMADGNPP 326
>UniRef50_Q4STY5 Cluster: Chromosome 10 SCAF14066, whole genome
shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 10
SCAF14066, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1645
Score = 124 bits (299), Expect = 4e-27
Identities = 93/303 (30%), Positives = 152/303 (50%), Gaps = 47/303 (15%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN-FAHI 148
FE + +G G G V K RH TG + A K+ ++V +++I E+ +L + +I
Sbjct: 52 FELVELVGNGTYGQVFKGRHVKTGQLAAIKV--MDVTGEEEEEIKAEINMLKNYSQHRNI 109
Query: 149 VGFYGAFYS------DGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLS 200
+YGAF D ++ + ME+ GS+ ++K K + E + I +L+GLS
Sbjct: 110 ATYYGAFVKKNPPGVDDQLWLVMEFCGAGSVTDLIKNTKGNSLKEEWIAYICREILRGLS 169
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL- 257
+L +H ++HRD+K N+L+ N E+K+ DFGVS QL ++ N+F+GT +M+PE +
Sbjct: 170 HLH-QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIA 228
Query: 258 ----QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
Y +SD+WSLG++ +EMA G P+ D + A+F
Sbjct: 229 CDENPEATYDFKSDLWSLGITAIEMAEGAPPL--CDMHPMRALF---------------- 270
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
I P P+L S +S +F+ F++ CL KN R + L+ H +IR
Sbjct: 271 ----------LIPRNPAPRLKSKKWSKKFQSFIEGCLVKNQRRRQSTEQLLGHPFIRDLP 320
Query: 374 AEK 376
E+
Sbjct: 321 NER 323
>UniRef50_Q23290 Cluster: Germinal center kinase family protein 2;
n=2; Caenorhabditis|Rep: Germinal center kinase family
protein 2 - Caenorhabditis elegans
Length = 829
Score = 124 bits (299), Expect = 4e-27
Identities = 85/307 (27%), Positives = 149/307 (48%), Gaps = 20/307 (6%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147
DD+E L +G G G V K R + + A K++ LE I +E+ V+ EC+ +
Sbjct: 13 DDYELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAV-IQQEIMVIRECSHPN 71
Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207
I+ ++G++ + I MEY GGSL I G + E + + L+GL+YL +
Sbjct: 72 IIAYFGSYIRRDRLWIVMEYCGGGSLQDIYHLTGPLSELQIAFVCRETLRGLNYLHNMGK 131
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL---QGTHY 262
I HRD+K +NIL++S+G++K+ DFGV+ Q+ ++ SF+GT +M+PE + Y
Sbjct: 132 I-HRDIKGANILLSSSGDVKLADFGVAAQITATIGKRKSFIGTPYWMAPEVACVEKRGGY 190
Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIF-EL 321
+Q D+W+ G++ +E +G P D + ++ + P + R +F +
Sbjct: 191 GMQCDVWATGITAIE--LGECQPPLFDLHPMQVLYLMTKSGYKPPHLKDKHRWTPLFHDF 248
Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAG 381
+ + + P K PS ++ L +P L M + + K D+
Sbjct: 249 VRQCLTKNPKKRPS----------PEKLLTSHPFVLGSLSARMTRDLLDKVNGAPTDVYD 298
Query: 382 WVCKTMD 388
+ KT+D
Sbjct: 299 RMSKTVD 305
>UniRef50_Q5U8Z0 Cluster: Misshapen/NIKs-related kinase isoform
beta; n=36; Euteleostomi|Rep: Misshapen/NIKs-related
kinase isoform beta - Homo sapiens (Human)
Length = 1312
Score = 124 bits (299), Expect = 4e-27
Identities = 94/303 (31%), Positives = 153/303 (50%), Gaps = 47/303 (15%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE-CNFAHI 148
FE + +G G G V K RH TG + A K+ ++V +++I +E+ +L + + +I
Sbjct: 25 FELVEVVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTEDEEEEIKQEINMLKKYSHHRNI 82
Query: 149 VGFYGAFY------SDGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLS 200
+YGAF +D ++ + ME+ GS+ ++K K + E + I +L+GL+
Sbjct: 83 ATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLA 142
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL- 257
+L H ++HRD+K N+L+ N E+K+ DFGVS QL ++ N+F+GT +M+PE +
Sbjct: 143 HLH-AHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIA 201
Query: 258 ----QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
Y +SDIWSLG++ +EMA G P+ D + A+F
Sbjct: 202 CDENPDATYDYRSDIWSLGITAIEMAEGAPPL--CDMHPMRALF---------------- 243
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
I PPP+L S +S +F DF+D CL K R + L+ +IR
Sbjct: 244 ----------LIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLSRPPTEQLLKFPFIRDQP 293
Query: 374 AEK 376
E+
Sbjct: 294 TER 296
>UniRef50_Q8N4C8 Cluster: Misshapen-like kinase 1; n=114;
Eumetazoa|Rep: Misshapen-like kinase 1 - Homo sapiens
(Human)
Length = 1332
Score = 124 bits (299), Expect = 4e-27
Identities = 94/303 (31%), Positives = 153/303 (50%), Gaps = 47/303 (15%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE-CNFAHI 148
FE + +G G G V K RH TG + A K+ ++V +++I +E+ +L + + +I
Sbjct: 25 FELVEVVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTEDEEEEIKQEINMLKKYSHHRNI 82
Query: 149 VGFYGAFY------SDGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLS 200
+YGAF +D ++ + ME+ GS+ ++K K + E + I +L+GL+
Sbjct: 83 ATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLA 142
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL- 257
+L H ++HRD+K N+L+ N E+K+ DFGVS QL ++ N+F+GT +M+PE +
Sbjct: 143 HLH-AHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIA 201
Query: 258 ----QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
Y +SDIWSLG++ +EMA G P+ D + A+F
Sbjct: 202 CDENPDATYDYRSDIWSLGITAIEMAEGAPPL--CDMHPMRALF---------------- 243
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
I PPP+L S +S +F DF+D CL K R + L+ +IR
Sbjct: 244 ----------LIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLSRPPTEQLLKFPFIRDQP 293
Query: 374 AEK 376
E+
Sbjct: 294 TER 296
>UniRef50_P38692 Cluster: Serine/threonine-protein kinase KIC1; n=2;
Saccharomyces cerevisiae|Rep: Serine/threonine-protein
kinase KIC1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 1080
Score = 124 bits (299), Expect = 4e-27
Identities = 87/294 (29%), Positives = 152/294 (51%), Gaps = 34/294 (11%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN-FAHI 148
F++ +G+G GVV K + TG + A K+++L+ + + RE++ L ++I
Sbjct: 23 FKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNI 82
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+YG++ D + I ME+ GGSL +L+ G+I E +G I +L L + K +
Sbjct: 83 TRYYGSYLKDTSLWIIMEHCAGGSLRSLLRP-GKIDEKYIGVIMRELLVALKCIH-KDNV 140
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPE-RLQGTHYSVQ 265
+HRD+K +N+L+ + G +K+CDFGV+ Q+ + + GT +M+PE ++G +Y +
Sbjct: 141 IHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTK 200
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYI 325
DIWSLG++ E+A G P D + L A+ +L+ I
Sbjct: 201 VDIWSLGITTYEIATGNPPY--CDVEALRAM-----------------------QLI--I 233
Query: 326 VNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDI 379
++P P+L +S K+F+ CL ++P ER L+ ++IR +A I
Sbjct: 234 KSKP-PRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPTSI 286
>UniRef50_Q33DX3 Cluster: Putative cyclic AMP-dependent protein
kinase catalytic subunit; n=1; Schizophyllum
commune|Rep: Putative cyclic AMP-dependent protein
kinase catalytic subunit - Schizophyllum commune
(Bracket fungus)
Length = 427
Score = 124 bits (298), Expect = 6e-27
Identities = 84/280 (30%), Positives = 141/280 (50%), Gaps = 11/280 (3%)
Query: 18 IDTNPAATPSNMTPQLKSA--TANERQGLAGKSKTSIEALTERLEQI----EMDDTQRRR 71
+D + + TP L SA T + +G +TS L+ + + E +D + R
Sbjct: 24 VDVGGSPYSTAPTPSLVSANTTLFDHRGSLSTQRTSFSELSGHRQGLGAIPEQEDMEARL 83
Query: 72 IEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKK 131
+ L + K G DF LG G+ G V+ VR K A K+++ E +K+
Sbjct: 84 NRLHLFSRNK-GIYRLQDFLIQRTLGTGSFGRVLLVRSKHNLRFYAIKVLNKEKVLRMKQ 142
Query: 132 --QIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILG 189
E +LH N I+ +GAF + + M+++ GG L +L+++ R PE +
Sbjct: 143 VEHTNNERNMLHRVNHNFIINLWGAFQDGNNLYMVMDFVPGGELFNLLRRSIRFPEPVAK 202
Query: 190 TITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTR 249
+ V L YL + I++RD+KP NIL+N++G IK+ DFG + +++D++A + GT
Sbjct: 203 FYAAEVSLALRYLHSNN-IIYRDLKPENILLNADGHIKVADFGFA-KIVDTVAYTLCGTP 260
Query: 250 SYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPD 289
Y++PE + G Y+ D ++LG+ EM G+ P PD
Sbjct: 261 DYLAPEIIWGGRYNKSVDWYALGVLCYEMLSGLPPFHTPD 300
>UniRef50_UPI00006CB840 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 1108
Score = 123 bits (297), Expect = 7e-27
Identities = 93/284 (32%), Positives = 149/284 (52%), Gaps = 36/284 (12%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149
+EK+ +GQG GVV + K T I+A K+ L++ + + E L + N +IV
Sbjct: 28 YEKVYRIGQGAFGVVYQAIDKFTDKIVAIKI--LKINSDLNSHLNEET-TLSDMNSKYIV 84
Query: 150 GFYGAFYS--DGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKH 206
Y + + EI + +E+ + GSL ++ G+ E+ + I VL+GL YL H
Sbjct: 85 KLYDKYIDAKNKEIWLVIEFCNMGSLADVINITGQTFFEAEIACILDNVLQGLDYLHKNH 144
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQS 266
MHRD+K +NIL+N+ GE K+ DFGV+ D A++FVG+ ++SPE+L Y+ +
Sbjct: 145 R-MHRDLKSANILLNNEGEAKLSDFGVASCKSD--ADTFVGSPYWLSPEQLNKQKYTNKV 201
Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326
DIW+LG+ ++EMA GM PP +G + +P IV
Sbjct: 202 DIWALGICIIEMAEGM---PP---------YGDLRPTSAMKMIKQNP-----------IV 238
Query: 327 NEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370
N P+ FSDE +F+ CL+ NP++R + L+NH++ +
Sbjct: 239 NFQDPQQ----FSDELNNFLCHCLQINPEDRWTAEQLLNHDFFK 278
>UniRef50_UPI000023D1D8 Cluster: hypothetical protein FG05484.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG05484.1 - Gibberella zeae PH-1
Length = 849
Score = 123 bits (297), Expect = 7e-27
Identities = 84/231 (36%), Positives = 128/231 (55%), Gaps = 23/231 (9%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAI------KKQII----RE 136
DD + K +GQG+ G V H TG ++A K + A KK +I RE
Sbjct: 572 DDKWMKGALIGQGSFGCVYLALHAVTGELLAVKQVETPAPGANSQGDNRKKGMIDALKRE 631
Query: 137 LKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVL 196
+ +L + +IV + G + ++I +EY+ GGS+ +L G +PE ++ + +L
Sbjct: 632 ISLLRDLRHPNIVQYLGCSSTADYLNIFLEYVPGGSVQTMLNSYGALPEPLVRSFVRQIL 691
Query: 197 KGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL----IDSMAN------SFV 246
GLSYL ++ I+HRD+K +NILV++ G IKI DFG+S +L I + AN S
Sbjct: 692 TGLSYLHNQD-IIHRDIKGANILVDNKGTIKISDFGISKKLEATNILNGANNSKHRPSLQ 750
Query: 247 GTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIF 297
G+ +M+PE ++ T Y+ ++DIWSLG +VEM G +P PD L AIF
Sbjct: 751 GSVFWMAPEVVKQTSYTRKADIWSLGCLVVEMMTGSHPF--PDCSQLQAIF 799
>UniRef50_Q0J228 Cluster: Os09g0383300 protein; n=5; Oryza
sativa|Rep: Os09g0383300 protein - Oryza sativa subsp.
japonica (Rice)
Length = 653
Score = 123 bits (297), Expect = 7e-27
Identities = 85/259 (32%), Positives = 136/259 (52%), Gaps = 15/259 (5%)
Query: 83 GELSDDDFEKLGEL-GQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQI---IREL- 137
GE S + GEL G G G V + TG ++A K + + A +++ IREL
Sbjct: 93 GEESPQIRWRKGELIGSGAFGQVYLGMNLDTGELLAVKQVLIGSNNATREKAQAHIRELE 152
Query: 138 ---KVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSA 194
K+L + +IV + G + ++I +E++ GGS+ +L K G PE+++ T
Sbjct: 153 EEVKLLKNLSHPNIVRYLGTVREEDTLNILLEFVPGGSIQSLLGKLGSFPEAVIRKYTKQ 212
Query: 195 VLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID----SMANSFVGTRS 250
+L+GL YL + +AI+HRD+K +NILV++ G IK+ DFG S Q+ + A + GT
Sbjct: 213 ILQGLEYLHN-NAIIHRDIKGANILVDNKGCIKLADFGASKQVAKLATITAAKTMKGTPH 271
Query: 251 YMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAP 310
+M+PE + G+ ++ +DIWS+G +++EMA G P + G + H P P
Sbjct: 272 WMAPEVIVGSGHNFSADIWSVGCTVIEMATGKPPWSQQYQEVALLFHVGTTKSHPP--IP 329
Query: 311 NSPRPMAIFELLDYIVNEP 329
P A LL + EP
Sbjct: 330 EHLSPEAKDFLLKCLQKEP 348
>UniRef50_Q869U1 Cluster: Similar to Arabidopsis thaliana (Mouse-ear
cress). Hypothetical 75.4 kDa protein; n=2;
Dictyostelium discoideum|Rep: Similar to Arabidopsis
thaliana (Mouse-ear cress). Hypothetical 75.4 kDa
protein - Dictyostelium discoideum (Slime mold)
Length = 1028
Score = 123 bits (297), Expect = 7e-27
Identities = 88/296 (29%), Positives = 150/296 (50%), Gaps = 36/296 (12%)
Query: 86 SDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE-VKPAIKKQIIRELKVLHECN 144
S D +E +G+G G+V + +A K+I LE K ++I +E++ + C+
Sbjct: 67 SADQYELKETIGKGGSGLVQRAICLPFQENVAIKIIDLEHCKNVSLEEIRKEIQAMSLCH 126
Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKA--GRIPESILGTITSAVLKGLSYL 202
++V ++ +F + + + M+++ GS I++ + E ++ TI LK + Y
Sbjct: 127 HPNVVAYHTSFVYNESLWVIMDFLSAGSCSDIMRFSFPQGFEEHVIATILKEALKAICYF 186
Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID---SMANSFVGTRSYMSPERLQG 259
K +HRD+K NIL++SNG I++ DFGVS LID + N+FVGT +M+PE ++
Sbjct: 187 H-KTGRIHRDIKSGNILIDSNGNIQLSDFGVSATLIDTGETSRNTFVGTPCWMAPEIMEQ 245
Query: 260 THYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIF 319
+Y DIWS G++ +E+A G P + P PM +
Sbjct: 246 VNYDYAVDIWSFGITALELARGKAPF---------------------AEYP----PMKV- 279
Query: 320 ELLDYIVNEPPPKLPSG--IFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
LL + N PP G +S FKD V++CL+K+P +R L+ H + ++A+
Sbjct: 280 -LLLTLQNPPPSLEGDGESKWSHSFKDLVEKCLQKDPSKRPLPSKLLEHRFFKQAK 334
>UniRef50_Q6CMA7 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome E of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome E of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 1016
Score = 123 bits (297), Expect = 7e-27
Identities = 73/200 (36%), Positives = 116/200 (58%), Gaps = 8/200 (4%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA-HI 148
F++ +G+G GVV K H T + A K+++L+ + I +E++ L +I
Sbjct: 16 FKRKEIIGRGKFGVVYKAFHVKTQQVYAIKVLNLDNTEDEVEDIRKEIQFLSSLKQTPNI 75
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGL-SYLRDKHA 207
+YG++ D ++ + MEY GGSL +L+ G I E +G I +L L S RD
Sbjct: 76 THYYGSYLIDTKLWVIMEYCAGGSLRTLLRP-GIIEEKYIGVIMREILVALISIHRDN-- 132
Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--ANSFVGTRSYMSPE-RLQGTHYSV 264
++HRD+K +NIL+ +NG +K+CDFGV+ QL SM + GT +M+PE ++G +Y
Sbjct: 133 VIHRDIKAANILIANNGSVKLCDFGVAAQLSQSMLKRQTMAGTPYWMAPEVIMEGVYYDT 192
Query: 265 QSDIWSLGLSLVEMAIGMYP 284
+ DIWSLG++ E+A G P
Sbjct: 193 KVDIWSLGITAYEIATGNPP 212
>UniRef50_A5DUG3 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 932
Score = 123 bits (297), Expect = 7e-27
Identities = 70/205 (34%), Positives = 118/205 (57%), Gaps = 6/205 (2%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC-NFAHI 148
+++ +G+G GVV K HK T I A K+++L+ + K + +E++ L E N +I
Sbjct: 7 YKRTEVIGRGKFGVVYKAYHKQTKQIYAIKVLNLDTEEEEIKDVQQEIQFLSELKNVPNI 66
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+YG+ D ++ I M+Y GGSL +LK G + E + IT +L LS + K +
Sbjct: 67 THYYGSILHDTKLWIVMDYCAGGSLRTLLKP-GVLEEKYIAIITRELLMTLSEVH-KMGV 124
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLI--DSMANSFVGTRSYMSPERLQ-GTHYSVQ 265
+HRD+K +N+L+ G +++CDFGV+ ++ + GT +M+PE ++ G Y+ +
Sbjct: 125 IHRDLKAANVLITKEGNVQLCDFGVAAKISSKSQRRTTMAGTPYWMAPEVIKSGETYNSK 184
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDA 290
+DIWSLG+++ E A G P DA
Sbjct: 185 ADIWSLGVTIYETATGNPPYCDKDA 209
>UniRef50_Q4QGB0 Cluster: Mitogen-activated protein kinase kinase 2;
n=7; Trypanosomatidae|Rep: Mitogen-activated protein
kinase kinase 2 - Leishmania major
Length = 1090
Score = 123 bits (296), Expect = 1e-26
Identities = 69/200 (34%), Positives = 113/200 (56%), Gaps = 5/200 (2%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR-ELKVLHECNFA 146
+D++ + +G+G+ G V K R K TG I+A K I + K + + +R E+++L + N
Sbjct: 6 EDYQIIESIGEGSFGKVYKARIKGTGQIVAMKFIVKKGKNEKELKNLRSEIEILTKLNHP 65
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
HI+ + +F +D + + MEY G D IL+ ++PE + I +++ L+YL
Sbjct: 66 HIIMLFDSFETDSDFVVVMEYAQGELYD-ILEDEKQLPEKEVQKIAKQLIQALNYLHSNR 124
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYSV 264
I+HRD+KP NIL+ NG +K+ DFG + + + + S GT YM+PE +Q Y
Sbjct: 125 -IIHRDMKPQNILIGQNGAVKLADFGFARSMSYNTIVLTSIKGTPLYMAPELVQERAYDN 183
Query: 265 QSDIWSLGLSLVEMAIGMYP 284
+ D+WSLG L E+ G P
Sbjct: 184 RVDLWSLGCILYELYYGKPP 203
>UniRef50_Q2H8Z5 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 865
Score = 123 bits (296), Expect = 1e-26
Identities = 88/236 (37%), Positives = 129/236 (54%), Gaps = 24/236 (10%)
Query: 83 GELSDDDFEKLGEL-GQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAI------KKQII- 134
GE DD G L GQG+ G V H TG ++A K + A KK +I
Sbjct: 583 GESWDDSKWMKGSLIGQGSFGSVYLALHAVTGELLAVKQVETPSPGANSQSDSRKKSMID 642
Query: 135 ---RELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTI 191
RE+ +L + +IV + G S ++I +EY+ GGS+ +L G +PE ++ +
Sbjct: 643 ALKREISLLRDLRHPNIVQYLGCGSSVEYLNIFLEYVAGGSVQTMLNSYGALPEPLIRSF 702
Query: 192 TSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL----IDSMAN---- 243
+L GLSYL ++ I+HRD+K +NILV++ G IKI DFG+S +L I + AN
Sbjct: 703 VRQILNGLSYLHNRD-IIHRDIKGANILVDNKGTIKISDFGISKKLEATNILNGANNNKH 761
Query: 244 --SFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIF 297
S G+ +M+PE ++ T Y+ ++DIWSLG +VEM G +P PD L AIF
Sbjct: 762 RPSLQGSVFWMAPEVVKQTSYTRKADIWSLGCLVVEMMTGQHPF--PDCTQLQAIF 815
>UniRef50_Q5EAR9 Cluster: Zgc:152783 protein; n=10;
Euteleostomi|Rep: Zgc:152783 protein - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 332
Score = 122 bits (295), Expect = 1e-26
Identities = 91/303 (30%), Positives = 154/303 (50%), Gaps = 47/303 (15%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE-CNFAHI 148
FE + +G G G V K RH TG + A K+ ++V +++I E+ +L + + +I
Sbjct: 25 FELVELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKAEINMLKKYSHHRNI 82
Query: 149 VGFYGAFYS------DGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLS 200
+YGAF D ++ + ME+ GS+ ++K K + E I +L+GL+
Sbjct: 83 ATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNSLKEEWTAYICREILRGLT 142
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL- 257
+L +H ++HRD+K N+L+ N E+K+ DFGVS QL ++ N+F+GT +M+PE +
Sbjct: 143 HLH-QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIA 201
Query: 258 ----QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
Y +SD+WSLG++ +EMA G P+ D + A+F
Sbjct: 202 CDENPDATYDFKSDLWSLGITAIEMAEGAPPL--CDMHPMRALF---------------- 243
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
I P P+L S +S +F+ F++ CL KN ++R + L+ H +I+
Sbjct: 244 ----------LIPRNPAPRLKSKKWSKKFQSFIESCLVKNHNQRPSTEQLIKHPFIKDLP 293
Query: 374 AEK 376
E+
Sbjct: 294 NER 296
>UniRef50_Q9STE0 Cluster: MAP3K epsilon 1 protein kinase; n=1;
Brassica napus|Rep: MAP3K epsilon 1 protein kinase -
Brassica napus (Rape)
Length = 1299
Score = 122 bits (295), Expect = 1e-26
Identities = 89/284 (31%), Positives = 148/284 (52%), Gaps = 37/284 (13%)
Query: 95 ELGQGNGGVVMKVRHKSTGLIMARKLIHLE-VKPAIKKQIIRELKVLHECNFAHIVGFYG 153
E+G+G G V G +A K + LE + I++E+ +L N +IV + G
Sbjct: 25 EIGKGAYGRVYIGLDLENGDFVAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIVKYLG 84
Query: 154 AFYSDGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLSYLRDKHAIMHR 211
+ + + I +EY++ GSL I+K K G PES++ + VL+GL YL ++ ++HR
Sbjct: 85 SLKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQ-GVIHR 143
Query: 212 DVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTHYSVQSDIW 269
D+K +NIL G +K+ DFGV+ +L ++ N S VGT +M+PE ++ + SDIW
Sbjct: 144 DIKGANILTTKEGLVKLADFGVATKLNEADVNTHSVVGTPYWMAPEVIEMSGVCAASDIW 203
Query: 270 SLGLSLVEMAIGMYPIPP-PDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNE 328
S+G +++E+ + +PP D + + A+F +D P P+S
Sbjct: 204 SVGCTVIEL---LTCVPPYYDLQPMPALFRIVQDDSPP--IPDS---------------- 242
Query: 329 PPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
S + DF+ +C KK+ +R D KTL++H WIR +
Sbjct: 243 ---------LSPDITDFLRQCFKKDSRQRPDAKTLLSHPWIRNS 277
>UniRef50_Q10EQ9 Cluster: Protein kinase domain containing protein,
expressed; n=4; Oryza sativa|Rep: Protein kinase domain
containing protein, expressed - Oryza sativa subsp.
japonica (Rice)
Length = 777
Score = 122 bits (295), Expect = 1e-26
Identities = 89/288 (30%), Positives = 151/288 (52%), Gaps = 42/288 (14%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHL---EVKPAIK-KQIIRELKVLHECNFAHIVGF 151
+G G G V + ++ TG + A K +++ + K A KQ+ +E+K L + +IV +
Sbjct: 393 IGSGTFGCVYEAANRHTGALCAMKEVNIIPDDAKSAESLKQLEQEIKFLSQFKHENIVQY 452
Query: 152 YGAFYSDGEISICMEYMDGGSLDLILKK-AGRIPESILGTITSAVLKGLSYLRDKHAIMH 210
YG+ Y + I +EY+ GS++ + + G + ES++ + T +LKGL++L + IMH
Sbjct: 453 YGSEYIEDRFYIYLEYVHPGSINKYVNQHCGAMTESVIRSFTRHILKGLAFLHSQK-IMH 511
Query: 211 RDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN-SFVGTRSYMSPERLQGT-----HYSV 264
RD+K +N+LV+ NG +K+ DFG++ L + N S GT +M+PE +Q T Y +
Sbjct: 512 RDIKGANLLVDVNGVVKLADFGMAKHLSTAAPNLSLKGTPYWMAPEVVQATLVKDVGYDL 571
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDY 324
DIWSLG +++EM G PP + + G P A+F++L
Sbjct: 572 AVDIWSLGCTIIEMFTGK---PP-----WSGLEG----------------PAAMFKVL-- 605
Query: 325 IVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKA 372
P +P + S E K+F+ C ++NP ER L+ H ++ +
Sbjct: 606 ---HKDPSIPDSL-SPEGKEFLRCCFRRNPAERPTASKLLEHPFVHNS 649
>UniRef50_Q55BN8 Cluster: Protein serine/threonine kinase; n=1;
Dictyostelium discoideum AX4|Rep: Protein
serine/threonine kinase - Dictyostelium discoideum AX4
Length = 418
Score = 122 bits (295), Expect = 1e-26
Identities = 69/202 (34%), Positives = 114/202 (56%), Gaps = 10/202 (4%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQI-IRELKVLHECNFA 146
D +E LG LG+G+ GVV K++ K G ++ K I E +KQ+ + E+ +L +
Sbjct: 2 DQYEILGALGKGSFGVVSKIKRKEDGRVLVWKEICYENMQEKEKQLLVNEVNILQKLKHQ 61
Query: 147 HIVGFYGAFYS--DGEISICMEYMDGGSLDLILKKAGR----IPESILGTITSAVLKGLS 200
+IV +Y + I ME+ GG L ++KK + E ++ +L L
Sbjct: 62 NIVRYYDRIIDKPSSRLYIIMEHCSGGDLSQLIKKCRNERTYMDEEVIWRTLLQILSALQ 121
Query: 201 YLRDKH--AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM-ANSFVGTRSYMSPERL 257
+ ++ I+HRD+KP N+ ++ N IK+ DFG++ L +S+ A++FVGT YMSPE++
Sbjct: 122 EIHNRKDGVILHRDIKPGNLFLDENKNIKLGDFGLAKILNESLYAHTFVGTPYYMSPEQI 181
Query: 258 QGTHYSVQSDIWSLGLSLVEMA 279
G Y+ +SD+WS+G + EMA
Sbjct: 182 HGLKYNERSDVWSVGCLIYEMA 203
>UniRef50_A2G0I5 Cluster: STE family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: STE family protein kinase
- Trichomonas vaginalis G3
Length = 340
Score = 122 bits (295), Expect = 1e-26
Identities = 65/202 (32%), Positives = 115/202 (56%), Gaps = 4/202 (1%)
Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE-VKPAIKKQIIRELKVLHECNF 145
+D+F+ + E+G+G G V ++ H +G +A K+++ E + + K+ +++E+ +L + N
Sbjct: 30 EDNFQIIREIGRGGFGAVYEMLHTQSGYRLAGKVVNEESMSSSAKQSLLKEIDLLKKINS 89
Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRD 204
+ V ++G + + I MEY D GS D+I + + E + VL G+ L
Sbjct: 90 PYTVQYFGNIIFNKQQMILMEYCDRGSFRDMIDYRNLCLTEKQAAIVIKDVLSGILILHT 149
Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTHY 262
KH ++HRD+K +NIL+ S+G I++ DFG+S N S +GT +M+PE + Y
Sbjct: 150 KHKVLHRDIKAANILLMSDGGIRLTDFGISRDFSGGTLNTMSSIGTPYWMAPEVINSQPY 209
Query: 263 SVQSDIWSLGLSLVEMAIGMYP 284
S +DIWS+G + +E+ G P
Sbjct: 210 SYPADIWSIGATTIELVEGAPP 231
Score = 35.5 bits (78), Expect = 2.5
Identities = 12/33 (36%), Positives = 20/33 (60%)
Query: 341 EFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
EFKDF+ + K+P R + L+ H WI++ +
Sbjct: 261 EFKDFIAHTMSKDPKNRCTIPQLLKHPWIQQVD 293
>UniRef50_A2ED12 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 429
Score = 122 bits (295), Expect = 1e-26
Identities = 69/207 (33%), Positives = 113/207 (54%), Gaps = 4/207 (1%)
Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQI--IRELKVLHECNFA 146
+++ + +G+G V K +H + L +A K I E+ KKQ+ IRE++++ + +
Sbjct: 16 NYQFIERIGRGGMASVWKAQHIPSKLFVAIKAIPKELIQNDKKQMRFIREVELMKQMDHP 75
Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206
IV Y + + MEY+ G+LD +++ G IPE ++G I + + L YL
Sbjct: 76 FIVQLYQTLEDENYHYLVMEYLPNGNLDDYIQEKGPIPEGMMGRIFAQIYSVLYYLHKVV 135
Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFV--GTRSYMSPERLQGTHYSV 264
I HRD+K N+L++ N I+I DFG+S +D F G++ YM+PE + Y +
Sbjct: 136 KISHRDLKAENVLLDQNYNIRIIDFGLSTTFVDENTEFFTRCGSQYYMAPEIFKNEPYKL 195
Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAK 291
SDIWSLG+ L MA+G P D++
Sbjct: 196 GSDIWSLGVLLYLMAVGKLPFKDTDSQ 222
>UniRef50_Q6FKH4 Cluster: Similar to sp|P38692 Saccharomyces
cerevisiae YHR102w NRK1 ser/thr protein kinase; n=1;
Candida glabrata|Rep: Similar to sp|P38692 Saccharomyces
cerevisiae YHR102w NRK1 ser/thr protein kinase - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 1072
Score = 122 bits (295), Expect = 1e-26
Identities = 85/294 (28%), Positives = 152/294 (51%), Gaps = 34/294 (11%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN-FAHI 148
F++ +G+G G+V K H T + A K+++L+ + + RE++ L +I
Sbjct: 16 FKRTEVIGRGKFGIVYKGYHVKTKQVYAIKVLNLDSSEDEVEDVQREIQFLASLKQIPNI 75
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+YG++ + I MEY GGSL +L+ G+I E +G I +L L + K +
Sbjct: 76 TRYYGSYLRGTSLWIIMEYCAGGSLRSLLRP-GKIDEKYIGVIMRELLVALKVIH-KDNV 133
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPE-RLQGTHYSVQ 265
+HRD+K +N+L+ + G++K+CDFGV+ QL + + GT +M+PE ++G +Y +
Sbjct: 134 IHRDIKAANVLITNEGQVKLCDFGVAAQLNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTK 193
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYI 325
DIWSLG++ E+A G P D + L A+ +L+ I
Sbjct: 194 VDIWSLGITAYEIATGNPPY--CDVEALRAM-----------------------QLI--I 226
Query: 326 VNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDI 379
++P P+L ++ + K+F+ CL ++P ER + L+ ++I+ +A I
Sbjct: 227 KSKP-PRLEERNYTPQLKEFIALCLDEDPQERLSAEELLKTKFIKTHKATPTTI 279
>UniRef50_Q59LK7 Cluster: Likely protein kinase; n=2;
Saccharomycetales|Rep: Likely protein kinase - Candida
albicans (Yeast)
Length = 891
Score = 122 bits (295), Expect = 1e-26
Identities = 75/250 (30%), Positives = 137/250 (54%), Gaps = 10/250 (4%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC-NFAHI 148
+++ +G+G GVV K ++K T I+A K+++L+ + + +E++ L E N +I
Sbjct: 9 YKRTEVIGRGKFGVVYKAQNKQTKQIVAIKVLNLDTEEDEVIDVQQEIQFLSELKNVPNI 68
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
+YG +D ++ I M+Y GGSL +LK AG + E + I +L LS + K +
Sbjct: 69 THYYGCILNDTKLWIIMDYCAGGSLRTLLK-AGVLEERYVAVIVRELLMTLSAVH-KLGV 126
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLI--DSMANSFVGTRSYMSPERLQ-GTHYSVQ 265
+HRD+K +N+L++ G +++CDFGV+ ++ + + GT +M+PE ++ G Y+ +
Sbjct: 127 IHRDLKAANVLISKEGNVQLCDFGVAAKITANSTKRTTMAGTPYWMAPEVIRTGDTYNSK 186
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYI 325
+DIWSLG+++ E+A G P DA + +P + A+ E +
Sbjct: 187 ADIWSLGITIYEIATGNPPYCDKDASWAMQLI----SKSTPPRLEGREFSQALKECIALC 242
Query: 326 VNEPPPKLPS 335
++E P + PS
Sbjct: 243 LDENPEERPS 252
>UniRef50_A7TL28 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 376
Score = 122 bits (295), Expect = 1e-26
Identities = 70/204 (34%), Positives = 110/204 (53%), Gaps = 4/204 (1%)
Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH-LE-VKPAIKKQIIRELKVLH 141
+L +DFE +LG+G G V VRHK +GLI A K+++ +E V ++KQ RE+ + +
Sbjct: 112 DLKLNDFEIGRKLGKGKFGKVYCVRHKPSGLICALKVMNKMEIVNFNVQKQFKREIDIQY 171
Query: 142 ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201
N ++ Y F+ + + MEY+ GG L +LKK G + + + L+Y
Sbjct: 172 HLNHKNLTKLYAFFHDSKNVYLVMEYLIGGELYKLLKKNGPMNDITASNYVYQMTDALNY 231
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVS-GQLIDSMANSFVGTRSYMSPERLQGT 260
+ K I+HRD+KP NIL+ N +IK+ DFG S + + GT Y+SPE +
Sbjct: 232 MH-KRKIIHRDLKPENILIGFNNQIKLTDFGWSIYNPNNQKRKTLCGTIDYLSPELISSR 290
Query: 261 HYSVQSDIWSLGLSLVEMAIGMYP 284
Y D+W+LG+ E+ +G P
Sbjct: 291 EYDENVDVWALGILTYELVVGAPP 314
Score = 37.1 bits (82), Expect = 0.82
Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 332 KLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371
K P + S E +D + LK P ER +L+ +MNH WI K
Sbjct: 333 KFPPNV-SSEARDLITNLLKVVPSERFNLQQVMNHPWIEK 371
>UniRef50_UPI00006CFE83 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 890
Score = 122 bits (294), Expect = 2e-26
Identities = 78/240 (32%), Positives = 129/240 (53%), Gaps = 10/240 (4%)
Query: 85 LSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQI---IRELKVLH 141
L+ DF LG LG+G+ G V V+ ST + A K++ +V +K+Q+ + E +L
Sbjct: 568 LAFKDFTILGALGKGSFGRVFLVQQNSTEELFAMKMLK-KVSLIMKRQLKYAVTECNILK 626
Query: 142 ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201
C +VG + AF + + + ++Y +GG L +++ R E ++ + Y
Sbjct: 627 RCKNPFVVGLHYAFQTPNHLYMVLDYCNGGVLLQHIQRESRFSELTARFFVCEIILAIEY 686
Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQG 259
L ++ I++RD+KP NIL++S+G IK+ DFG+S + + + SF G+ +Y+SPE L G
Sbjct: 687 LHSQN-ILYRDLKPENILISSDGHIKLTDFGLSKEHVADFDVTKSFCGSPAYLSPEMLLG 745
Query: 260 THYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNED-HSPGQAPNSPRPMAI 318
+S SDI+ +G L EM G P D K L + G ++ED P NS + + I
Sbjct: 746 KGFSKASDIYGIGCVLYEMLTGQPPFFHEDIKQLYS--GIKSEDPQLPKYLSNSAKTLII 803
>UniRef50_Q56A46 Cluster: Zgc:113355; n=3; Clupeocephala|Rep:
Zgc:113355 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 488
Score = 122 bits (294), Expect = 2e-26
Identities = 80/219 (36%), Positives = 122/219 (55%), Gaps = 13/219 (5%)
Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEV--KPAIKKQIIRELKVLHECNF 145
+ ++K+ LGQG GVV ++H T + A K IH++ K K +++E VL
Sbjct: 2 EKYDKVLTLGQGGAGVVSLMKHVDTKKLCAVKRIHVDSSRKTKTKDVVLQEAIVLRSLKH 61
Query: 146 AHIVGFYGAFY--SDGEISICMEYMDGGSLDLILK--KAGR-IPESILGTITSAVLKGLS 200
HI+ + F+ ++ I I M+Y DGG+LD +K K G ES + V+ +S
Sbjct: 62 PHIITWIDTFFDATNESIYIVMDYCDGGTLDDHIKEQKCGEHFTESNIMDWFVQVVMAVS 121
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS--MANSFVGTRSYMSPERLQ 258
Y+ + I+HRD+KPSN+L+ G IK+ DFG+S + + MA++ VGT SY+SPE Q
Sbjct: 122 YIHSEK-ILHRDIKPSNVLLTKRGVIKLGDFGISKIMNHTLDMASTCVGTPSYLSPELCQ 180
Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIF 297
YS +SDIW++G L E+ P AK L ++F
Sbjct: 181 DVPYSTKSDIWAVGCLLYELCALK---PAFQAKNLLSLF 216
>UniRef50_Q584V3 Cluster: Protein kinase, putative; n=1; Trypanosoma
brucei|Rep: Protein kinase, putative - Trypanosoma
brucei
Length = 639
Score = 122 bits (294), Expect = 2e-26
Identities = 90/293 (30%), Positives = 145/293 (49%), Gaps = 41/293 (13%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARK--LIHLEVKPAIKKQII---RELKVLHECNFAHIVG 150
+G+G G V + TG +A K ++ ++ +KQ+ RE++V+ + N HIV
Sbjct: 246 IGRGMFGDVFRATDLDTGAELAVKQIIVSSDIDRDTEKQLCALEREIRVMRKLNHKHIVK 305
Query: 151 FYGAFYSDG--EISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
++ + +G + I MEY+ GG++ LK G + E T +L+GL+YL K I
Sbjct: 306 YFSSRRDEGCCALLIYMEYISGGTIASKLKTEGALSEEETRNYTRQLLEGLAYLH-KRRI 364
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA-NSFVGTRSYMSPERLQGTHYSVQSD 267
+HRD+K N+ + NG +K+ DFG S L ++ NS GT ++M+PE + + +S +D
Sbjct: 365 VHRDLKGDNLFITGNGVLKVGDFGTSKDLQSTIVTNSVAGTPNFMAPEVINCSGHSYTAD 424
Query: 268 IWSLGLSLVEMAIGMYPIPPPD--AKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYI 325
IWS+G ++EM G P D + AI G+ E H
Sbjct: 425 IWSVGCCVLEMLTGHPPFWQLDNCMAVMFAILRGELERHI-------------------- 464
Query: 326 VNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR-KAEAEKV 377
P LP G K+F+ +C + NP ER + L+ H WI+ K +A+ V
Sbjct: 465 ----PEHLPEGA-----KEFIRQCTRTNPRERLTARQLLRHPWIKGKGKADSV 508
>UniRef50_Q19KC5 Cluster: P21-activated kinase MAX-2; n=4;
Caenorhabditis|Rep: P21-activated kinase MAX-2 -
Caenorhabditis elegans
Length = 598
Score = 122 bits (294), Expect = 2e-26
Identities = 94/366 (25%), Positives = 169/366 (46%), Gaps = 36/366 (9%)
Query: 14 PPGSIDTNPAATPSNMTPQLKSATANERQGLAGKSKTSIEALTERLEQIEMDDTQRRRIE 73
PP P P + ++ G +KT++E + + + R ++
Sbjct: 248 PPVPGSKGPPVPPKPSKENSNDKSVGDKNGNTTTNKTTVEPPPPEEPPVRVRASHREKLS 307
Query: 74 --VFLCQKEKIGELSDD--DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAI 129
L Q +I S+ +E ++G G G V + ++A K + + +P
Sbjct: 308 DSEVLNQLREIVNPSNPLGKYEMKKQIGVGASGTVFVANVAGSTDVVAVKRMAFKTQPK- 366
Query: 130 KKQIIRELKVLHECNFAHIVGFYGAFYSDGE-ISICMEYMDGGSLDLILKKAGRIPESIL 188
K+ ++ E+KV+ + ++V + ++ D + + + M+Y++GG+L ++ K + E +
Sbjct: 367 KEMLLTEIKVMKQYRHPNLVNYIESYLVDADDLWVVMDYLEGGNLTDVVVKT-ELDEGQI 425
Query: 189 GTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID-SMANSFVG 247
+ LK L +L +H+I+HRD+K N+L+ NGE+K+ D G Q+ S ++ VG
Sbjct: 426 AAVLQECLKALHFLH-RHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVG 484
Query: 248 TRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPG 307
T +MSPE L Y+ + DIWSLG+ MA+ M PP +
Sbjct: 485 TPYWMSPEILNKKQYNYKVDIWSLGI----MALEMIDGEPPYLRET-------------- 526
Query: 308 QAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHE 367
P+ L+ N P S EF +F+D+CL +PD+RAD L+ H
Sbjct: 527 -------PLKAIYLIAQ--NGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHP 577
Query: 368 WIRKAE 373
+++KA+
Sbjct: 578 FLKKAK 583
>UniRef50_Q6FSC4 Cluster: Similar to sp|P08458 Saccharomyces
cerevisiae YDR523c SPS1 ser/thr protein kinase; n=1;
Candida glabrata|Rep: Similar to sp|P08458 Saccharomyces
cerevisiae YDR523c SPS1 ser/thr protein kinase - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 521
Score = 122 bits (294), Expect = 2e-26
Identities = 72/205 (35%), Positives = 114/205 (55%), Gaps = 6/205 (2%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155
+G+GN G V K + ++A K+++LE + + +E+ L E ++ +
Sbjct: 11 IGRGNFGDVYKAKDTWLNEVVAVKVVNLENSEEEVELLAQEIFFLAELKSPYVTNYIATV 70
Query: 156 YSDGEISICMEYMDGGSLDLILKK--AGRIPESILGTITSAVLKGLSYLRDKHAIMHRDV 213
D + I MEY GGS+ +LK +PE IT +LKGLSYL + I HRD+
Sbjct: 71 VEDVSMWIAMEYCGGGSVGDLLKYHYTSGLPEHKTRFITREILKGLSYLHSQRKI-HRDI 129
Query: 214 KPSNILVNSNGEIKICDFGVSGQLIDSM-ANSFVGTRSYMSPERL--QGTHYSVQSDIWS 270
K +NIL+ G++K+ DFGVSG+L+ S ++FVGT +M+PE + Y ++DIWS
Sbjct: 130 KAANILLTDEGKVKLSDFGVSGKLLSSFRRDTFVGTPYWMAPEIVAHDSEGYDERADIWS 189
Query: 271 LGLSLVEMAIGMYPIPPPDAKTLAA 295
LG++++EM G P+ D + A
Sbjct: 190 LGITVIEMLRGSPPLSKYDPMKVIA 214
>UniRef50_Q68ST5 Cluster: P21 activated kinase-like protein; n=18;
Agaricomycotina|Rep: P21 activated kinase-like protein -
Pleurotus djamor
Length = 658
Score = 122 bits (294), Expect = 2e-26
Identities = 88/291 (30%), Positives = 151/291 (51%), Gaps = 18/291 (6%)
Query: 20 TNPAATPSNMT---PQLKSATANERQGLAGKSKTSIEALTERLEQIEMDDTQRRRIEVFL 76
T PA+ P+ T P +K ++ + + K + +E + +RI
Sbjct: 306 TQPASGPAGATAGPPPVKPLQPTKKVQIQAEEKPKTTGVAAAAAALEKPKEKEKRISTMT 365
Query: 77 CQK--EKIGEL-SDDD----FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAI 129
+ EK+ ++ SD+D + K+ ++GQG G V + +TG +A K + L +P
Sbjct: 366 EVQIMEKLRQVVSDEDPKTIYSKIKKVGQGASGHVYVAKTLATGKKVAIKEMDLSHQPR- 424
Query: 130 KKQIIRELKVLHECNFAHIVGFYGAFY-SDGEISICMEYMDGGSLDLILKKAGRIPESIL 188
K+ I+ E+ V+ E +IV F ++ E+ + MEYM+GG+L I++ + E +
Sbjct: 425 KELIVNEILVMKESQHPNIVNFLESYLVKSNELWVVMEYMEGGALTDIIEN-NTLEEDQI 483
Query: 189 GTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFV 246
+I KGL +L + +I+HRD+K N+L+++ G +KI DFG +L D S + V
Sbjct: 484 ASICFETCKGLGHLHSQ-SIIHRDIKSDNVLLDAQGRVKITDFGFCAKLTDQKSKRATMV 542
Query: 247 GTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIF 297
GT +M+PE ++ Y + DIWSLG+ +EM I P P D + L A++
Sbjct: 543 GTPYWMAPEVVKQKEYGAKVDIWSLGIMAIEM-IENEP-PYLDEEPLKALY 591
>UniRef50_Q6FN53 Cluster: Serine/threonine-protein kinase STE20;
n=1; Candida glabrata|Rep: Serine/threonine-protein
kinase STE20 - Candida glabrata (Yeast) (Torulopsis
glabrata)
Length = 915
Score = 122 bits (294), Expect = 2e-26
Identities = 80/286 (27%), Positives = 144/286 (50%), Gaps = 8/286 (2%)
Query: 4 MSKNKLNLTLPPGSIDTNPAATPSNMTP-QLKSATANERQGLAGKSKTSIEALTERLEQI 62
+SK +L P ++ + ++ P +++ T + K+ ++ A R
Sbjct: 531 LSKKNASLPKLPSDDSSSHKKSATDSAPTSVETDTETVKVPPIPKTTPTVPAKASRRSNE 590
Query: 63 EMDDTQRRRIEVFLCQKEKIGELSD--DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKL 120
+ + + R ++ + +I D + L ++GQG G V + +A K
Sbjct: 591 KKKEERERNKKLLYAKLTEICSPGDPKSKYRDLIKIGQGASGGVYIAHDTESEDSVAIKQ 650
Query: 121 IHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKA 180
++LE +P K+ I+ E+ V+ E ++IV F ++ + G++ I MEYM+GGSL ++
Sbjct: 651 MNLEKQPK-KELILNEILVMRESKHSNIVNFIDSYLAKGDLWIVMEYMEGGSLTDVVTHC 709
Query: 181 GRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS 240
+ E +G + LKGL +L K ++HRD+K NIL++ G IK+ DFG Q+ ++
Sbjct: 710 -LLSEGQIGAVCRETLKGLQFLHSK-GVLHRDIKSDNILLSLKGNIKLTDFGFCAQINEN 767
Query: 241 --MANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284
+ VGT +M+PE + Y + DIWSLG+ ++EM G P
Sbjct: 768 NLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPP 813
>UniRef50_O95819 Cluster: Mitogen-activated protein kinase kinase
kinase kinase 4; n=25; Euteleostomi|Rep:
Mitogen-activated protein kinase kinase kinase kinase 4
- Homo sapiens (Human)
Length = 1239
Score = 122 bits (294), Expect = 2e-26
Identities = 93/303 (30%), Positives = 152/303 (50%), Gaps = 47/303 (15%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE-CNFAHI 148
FE + +G G G V K RH TG + A K+ ++V +++I E+ +L + + +I
Sbjct: 25 FELVEVVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTEDEEEEIKLEINMLKKYSHHRNI 82
Query: 149 VGFYGAFYS------DGEISICMEYMDGGSLDLILK--KAGRIPESILGTITSAVLKGLS 200
+YGAF D ++ + ME+ GS+ ++K K + E + I+ +L+GL+
Sbjct: 83 ATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLA 142
Query: 201 YLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPERL- 257
+L H I HRD+K N+L+ N E+K+ DFGVS QL ++ N+F+GT +M+PE +
Sbjct: 143 HLHIHHVI-HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIA 201
Query: 258 ----QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313
Y +SD+WS G++ +EMA G P+ D + A+F
Sbjct: 202 CDENPDATYDYRSDLWSCGITAIEMAEGAPPL--CDMHPMRALF---------------- 243
Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAE 373
I PPP+L S +S +F F++ CL KN +R + L+ H +IR
Sbjct: 244 ----------LIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQP 293
Query: 374 AEK 376
E+
Sbjct: 294 NER 296
>UniRef50_O76039 Cluster: Cyclin-dependent kinase-like 5; n=22;
Deuterostomia|Rep: Cyclin-dependent kinase-like 5 - Homo
sapiens (Human)
Length = 1030
Score = 122 bits (294), Expect = 2e-26
Identities = 91/289 (31%), Positives = 147/289 (50%), Gaps = 19/289 (6%)
Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMA-RKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148
FE LG +G+G GVV+K RHK T I+A +K E +K+ +RELK+L +I
Sbjct: 13 FEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENI 72
Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208
V AF G++ + EY++ L+L+ + +P + + ++K + + K+ I
Sbjct: 73 VELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCH-KNDI 131
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLID-SMAN--SFVGTRSYMSPERLQGTHYSVQ 265
+HRD+KP N+L++ N +K+CDFG + L + + AN +V TR Y SPE L G Y
Sbjct: 132 VHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKS 191
Query: 266 SDIWSLGLSLVEMAIGMYPIPPPDAK-----TLAAIFGGQNEDHSPGQAPNSPRPMAIFE 320
D+WS+G L E++ G P+ P +++ T+ + G + N PR F
Sbjct: 192 VDMWSVGCILGELSDGQ-PLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSN-PR----FH 245
Query: 321 LLDY-IVNEPP--PKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNH 366
L + VN P + GI + D + LK +P +R + +NH
Sbjct: 246 GLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNH 294
>UniRef50_UPI00006CDDE2 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 794
Score = 122 bits (293), Expect = 2e-26
Identities = 92/288 (31%), Positives = 144/288 (50%), Gaps = 35/288 (12%)
Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIK-KQIIRELKVLHECNFAHIVGFYGA 154
LG+G G V+ +K+TG I+A KLI + K K II E+K+L + +IV +YG
Sbjct: 159 LGKGTFGTVVLGHNKNTGEIVAVKLIETQYDRKQKYKSIIDEVKILKQMRHKNIVRYYGI 218
Query: 155 --FYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRD 212
+ I I EY+ GGSL +++K G+ E ++ T+ +L GL YL H I HRD
Sbjct: 219 QEHKAKDHIGIVCEYVSGGSLWRLIQKFGKFSEPLIRKYTTDILYGLQYLH-YHGITHRD 277
Query: 213 VKPSNILVNSNGEIKICDFG----VSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDI 268
+K +NILV+S+G K+ DFG +S ++ + GT ++M+PE + SDI
Sbjct: 278 IKGANILVDSDGVCKLADFGLAKSISQEIDEGQLKLPQGTPNWMAPEVCRSGTCRF-SDI 336
Query: 269 WSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNE 328
WSLG ++ EM G P A+T+ G ++ +
Sbjct: 337 WSLGCTVYEMITGKPPFSNFLAETIILRVG--------------------------LLKQ 370
Query: 329 PPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEK 376
PP L + S++ DF+ C + P+ER ++ L+ H +I + EK
Sbjct: 371 PPQFLENLQISEKLSDFLLHCFQIKPEERWNVDQLLQHPFIVDTDIEK 418
>UniRef50_Q4RZ52 Cluster: Chromosome 7 SCAF14966, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 7 SCAF14966, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1142
Score = 122 bits (293), Expect = 2e-26
Identities = 83/277 (29%), Positives = 145/277 (52%), Gaps = 37/277 (13%)
Query: 108 RHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEY 167
R+K TG++ A K I + + ++ ++ E+ +L +C+ +IV AFY D + I +E+
Sbjct: 28 RNKETGVLAAAKQIETKSEEELEDYMV-EIDILAKCDHRYIVKLLDAFYYDNTLWIMIEF 86
Query: 168 MDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEI 226
GG++D I+ + R + E + + +L+ L+YL I+HRD+K NIL+ +G+I
Sbjct: 87 CPGGAVDAIMLELDRGLTEPQIKVVCRQMLEALTYLHSMK-IIHRDLKAGNILLMLDGDI 145
Query: 227 KICDFGVSGQLIDSM--ANSFVGTRSYMSP-----ERLQGTHYSVQSDIWSLGLSLVEMA 279
K+ DFGVS + ++ +SF+GT +M+P E ++ Y ++DIWSLG++L+E+A
Sbjct: 146 KLADFGVSAKNNKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIELA 205
Query: 280 IGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFS 339
I PP + PM + LL ++PP +S
Sbjct: 206 ----QIEPPH---------------------HELNPMRV--LLKIAKSDPPALEQQHKWS 238
Query: 340 DEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEK 376
+FKDF+ + L KNP+ R L+ H ++R + +
Sbjct: 239 QDFKDFLKKALDKNPETRPSAVQLLQHPFVRSVTSNR 275
>UniRef50_A0DBL2 Cluster: Chromosome undetermined scaffold_44, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_44,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 382
Score = 122 bits (293), Expect = 2e-26
Identities = 92/281 (32%), Positives = 144/281 (51%), Gaps = 33/281 (11%)
Query: 92 KLGEL-GQGNGGVVMKVRHKSTGLIMARKLIHLE-VKPAIKKQIIRELKVLHECNFAHIV 149
K GEL GQG+ G V K TG I+A K I L+ V + +E+K+L + +IV
Sbjct: 64 KRGELIGQGSFGRVFKCMDIKTGRILAVKQIELDYVDKESLESFHQEIKILQQLKHKNIV 123
Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAG-RIPESILGTITSAVLKGLSYLRDKHAI 208
+YG +SI +EY+ GGS+ +++K ++ E ++ + +L GL YL +K I
Sbjct: 124 EYYGCDEDRSHLSILLEYVGGGSISHMMRKFKLKLQEPVIQKYVTDILHGLVYLHNK-GI 182
Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDI 268
+HRD+K +NI+V++ G K+ DFG S +I A S GT ++M+PE + SDI
Sbjct: 183 IHRDIKGANIIVDTKGVCKLADFGCS--IIGVNAYSLKGTPNWMAPEVINSQETGRYSDI 240
Query: 269 WSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNE 328
WSLG +++EM G PP + SP QA L+ +
Sbjct: 241 WSLGCTIIEMLTG----EPPWGRF-----------QSPMQA-----------LMTISSKQ 274
Query: 329 PPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369
P +P+ I S DF+++CL+ + +R K L+ H +I
Sbjct: 275 CSPPIPNNI-SQNLMDFLNKCLQFDHKKRWKAKQLLQHPFI 314
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.316 0.134 0.391
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 483,731,916
Number of Sequences: 1657284
Number of extensions: 21204957
Number of successful extensions: 91557
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 6611
Number of HSP's successfully gapped in prelim test: 4699
Number of HSP's that attempted gapping in prelim test: 65049
Number of HSP's gapped (non-prelim): 16692
length of query: 403
length of database: 575,637,011
effective HSP length: 102
effective length of query: 301
effective length of database: 406,594,043
effective search space: 122384806943
effective search space used: 122384806943
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 74 (33.9 bits)
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