BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001458-TA|BGIBMGA001458-PA|IPR002290|Serine/threonine protein kinase, IPR000719|Protein kinase, IPR008271|Serine/threonine protein kinase, active site, IPR011009|Protein kinase-like (403 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 262 8e-71 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 240 2e-64 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 226 4e-60 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 163 4e-41 SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 151 2e-37 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 127 3e-30 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 121 2e-28 SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 120 5e-28 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 118 1e-27 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 113 3e-26 SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosa... 112 7e-26 SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|... 111 1e-25 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 108 2e-24 SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosac... 104 3e-23 SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 101 1e-22 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 100 3e-22 SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizo... 100 3e-22 SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizo... 100 7e-22 SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 99 1e-21 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 99 1e-21 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 97 5e-21 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 94 3e-20 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 93 5e-20 SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 93 5e-20 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 92 1e-19 SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 90 6e-19 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 89 1e-18 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 88 2e-18 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 88 2e-18 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 87 4e-18 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 87 6e-18 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 86 7e-18 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 86 1e-17 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 85 1e-17 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 85 2e-17 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 85 2e-17 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 83 5e-17 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 82 1e-16 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 82 1e-16 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 81 2e-16 SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|S... 80 6e-16 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 79 8e-16 SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase... 79 1e-15 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 79 1e-15 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 79 1e-15 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 78 3e-15 SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizo... 78 3e-15 SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schiz... 76 1e-14 SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Sch... 75 1e-14 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 75 1e-14 SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomy... 75 2e-14 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 74 3e-14 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 74 3e-14 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 73 7e-14 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 73 1e-13 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 73 1e-13 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 72 2e-13 SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosac... 72 2e-13 SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 71 3e-13 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 71 4e-13 SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosac... 70 7e-13 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 69 1e-12 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 69 1e-12 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 69 2e-12 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 69 2e-12 SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Pp... 68 2e-12 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 68 3e-12 SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosac... 67 5e-12 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 65 2e-11 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 64 4e-11 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 62 1e-10 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 62 1e-10 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 62 2e-10 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 61 3e-10 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 59 1e-09 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 57 4e-09 SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase ... 57 5e-09 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 56 9e-09 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 53 8e-08 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 52 1e-07 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 52 2e-07 SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizo... 50 6e-07 SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizos... 49 1e-06 SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Sch... 48 3e-06 SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizo... 46 1e-05 SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schiz... 45 2e-05 SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 45 2e-05 SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces p... 41 4e-04 SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosa... 40 8e-04 SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schi... 39 0.001 SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces po... 39 0.001 SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosac... 38 0.003 SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizos... 37 0.006 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 37 0.006 SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosacchar... 37 0.006 SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizos... 36 0.008 SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosa... 36 0.008 SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosa... 36 0.010 SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizos... 33 0.072 SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizo... 30 0.51 SPAC6G9.06c |pcp1||pericentrin Pcp1|Schizosaccharomyces pombe|ch... 29 0.88 SPAC15A10.13 |ppk3||serine/threonine protein kinase Ppk3|Schizos... 29 1.5 SPBC4C3.05c |nuc1|rpa1|DNA-directed RNA polymerase I complex lar... 28 2.7 SPBC23G7.08c |rga7||GTPase activating protein Rga7|Schizosacchar... 28 2.7 SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosa... 28 2.7 SPAC4F10.05c |||mitochondrial lipoate-protein ligase |Schizosacc... 27 4.7 SPBC1826.01c |mot1||TATA-binding protein associated factor Mot1|... 27 4.7 SPBC1734.15 |rsc4|brd1|RSC complex subunit Rsc4|Schizosaccharomy... 27 6.2 SPBPJ4664.02 |||glycoprotein |Schizosaccharomyces pombe|chr 2|||... 26 8.2 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 262 bits (641), Expect = 8e-71 Identities = 140/301 (46%), Positives = 194/301 (64%), Gaps = 25/301 (8%) Query: 82 IGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLH 141 I +L + E + LG+GNGG V V+H++ + MARK +++ ++KQI+REL VLH Sbjct: 58 ISDLDNSSLEVVRHLGEGNGGAVSLVKHRN--IFMARKTVYVGSDSKLQKQILRELGVLH 115 Query: 142 ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201 C +IVGFYGAF IS+CMEYMD GSLD IL++ G IP ILG I ++++KGL Y Sbjct: 116 HCRSPYIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILGKIINSMVKGLIY 175 Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH 261 L + I+HRD+KPSN++VNS GEIK+CDFGVSG+L++S+A +FVGT +YMSPER++G Sbjct: 176 LYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGELVNSVAQTFVGTSTYMSPERIRGGK 235 Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321 Y+V+SDIWSLG+S++E+A P + N D S G I +L Sbjct: 236 YTVKSDIWSLGISIIELATQELP------------WSFSNIDDSIG----------ILDL 273 Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAG 381 L IV E PP+LPS F ++ + FVD CL K+P RA + L + ++A VD+A Sbjct: 274 LHCIVQEEPPRLPSS-FPEDLRLFVDACLHKDPTLRASPQQLCAMPYFQQALMINVDLAS 332 Query: 382 W 382 W Sbjct: 333 W 333 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 240 bits (588), Expect = 2e-64 Identities = 133/298 (44%), Positives = 184/298 (61%), Gaps = 34/298 (11%) Query: 92 KLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGF 151 KL ELG+GN GVV K H+ TG+ MA K I L ++ A QII EL +LH+ +IV F Sbjct: 322 KLEELGKGNYGVVYKALHQPTGVTMALKEIRLSLEEATFNQIIMELDILHKAVSPYIVDF 381 Query: 152 YGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHR 211 YGAF+ +G + ICMEYMD GS+D L G E +L AV++GL L+++H I+HR Sbjct: 382 YGAFFVEGSVFICMEYMDAGSMDK-LYAGGIKDEGVLARTAYAVVQGLKTLKEEHNIIHR 440 Query: 212 DVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQ------GT-HYSV 264 DVKP+N+LVNSNG++K+CDFGVSG L+ S++ + +G +SYM+PER++ G Y+V Sbjct: 441 DVKPTNVLVNSNGQVKLCDFGVSGNLVASISKTNIGCQSYMAPERIRVGGPTNGVLTYTV 500 Query: 265 QSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDY 324 Q+D+WSLGL+++EMA+G YP PP ++ +IF +L Sbjct: 501 QADVWSLGLTILEMALGAYPYPP---ESYTSIFA---------------------QLSAI 536 Query: 325 IVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDIAGW 382 +PP LP FS E +DFV++CL KNP R D L NH W+ K + VD+A W Sbjct: 537 CDGDPP-SLPDS-FSPEARDFVNKCLNKNPSLRPDYHELANHPWLLKYQNADVDMASW 592 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 226 bits (553), Expect = 4e-60 Identities = 127/296 (42%), Positives = 176/296 (59%), Gaps = 33/296 (11%) Query: 93 LGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFY 152 + LG+G G V K R + T +I A K + A++KQ++RELK+ C +IV +Y Sbjct: 82 MNSLGEGVSGSVRKCRIRGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCTSPYIVKYY 141 Query: 153 GAFYSDGE--ISICMEYMDGGSLDLILKKA----GRIPESILGTITSAVLKGLSYLRDKH 206 GA Y++ E ++I MEY GSLD I K+ GR E LG I VL GLSYL D+ Sbjct: 142 GACYNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLSGLSYLHDRK 201 Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQS 266 I+HRD+KPSNIL+ S G++K+CDFGVSG+L++S+A +F GT YM+PER+ G Y++ S Sbjct: 202 -IIHRDIKPSNILLTSKGQVKLCDFGVSGELVNSLAGTFTGTSYYMAPERISGGSYTISS 260 Query: 267 DIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIV 326 DIWSLGL+L+E+A+ +P PP SP PM I ELL YI+ Sbjct: 261 DIWSLGLTLMEVALNRFPFPP----------------------EGSPPPMPI-ELLSYII 297 Query: 327 NEPPPKLPS--GI-FSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEKVDI 379 N PPP LP GI +S F+ F+ CL K+ R + ++ H W++ E VD+ Sbjct: 298 NMPPPLLPQEPGIKWSKSFQHFLCVCLDKDKTRRPGPQKMLTHPWVKAFERIHVDM 353 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 163 bits (396), Expect = 4e-41 Identities = 113/295 (38%), Positives = 163/295 (55%), Gaps = 34/295 (11%) Query: 85 LSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN 144 L+ + + L +LG G+ GVV K R +G I+A K I LE I +E+ +L CN Sbjct: 4 LNANSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCN 63 Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRD 204 ++++ +YG F + I ME+MDGGS+ +L K GR+ E ++ I VL GL+YL Sbjct: 64 SSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLL-KMGRLNEQVISIILREVLYGLNYLHG 122 Query: 205 KHAIMHRDVKPSNILVNSN-GEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTH 261 ++ I HRD+K +NIL++S+ G +K+ DFGV+ QL + S ++FVGT +M+PE +Q T Sbjct: 123 QNKI-HRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTS 181 Query: 262 YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFEL 321 Y + +DIWSLG++ +EMA G IPP +A P IFE Sbjct: 182 YGLAADIWSLGITAIEMANG---IPP--------------------RATMHPM-RVIFE- 216 Query: 322 LDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRKAEAEK 376 I PPKL FS F+DFV CL NP+ R K L+ H +I+ A K Sbjct: 217 ---IPQSEPPKLDDH-FSPTFRDFVSCCLDLNPNMRWSAKELLQHPFIKSAGTVK 267 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 151 bits (365), Expect = 2e-37 Identities = 98/284 (34%), Positives = 148/284 (52%), Gaps = 31/284 (10%) Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149 + L +GQG+ G V + + + I+A K++ L+ + + +E+ L + N HI Sbjct: 6 YRDLQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHIT 65 Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIM 209 +Y +F + I MEY DGGS +LK +G E ++ + VL+ L YL + M Sbjct: 66 KYYASFVDGFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQ-GKM 124 Query: 210 HRDVKPSNILVNSNGEIKICDFGVSGQL--IDSMANSFVGTRSYMSPERLQGTHYSVQSD 267 HRD+K +NIL +G +K+ DFGVSGQL + + FVGT +M+PE ++ T Y+ ++D Sbjct: 125 HRDIKAANILTMKDGLVKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVVKQTGYNYKAD 184 Query: 268 IWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVN 327 IWSLG++ E+A G PP + G + PM + L I Sbjct: 185 IWSLGITAYELATG----EPP--------YSGIH-------------PMKVLLL---IPK 216 Query: 328 EPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371 PP L FS F DFV CLKKNP +RA + L H++I+K Sbjct: 217 HSPPSLERSKFSRAFCDFVSNCLKKNPKDRATAEYLSKHKFIKK 260 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 127 bits (306), Expect = 3e-30 Identities = 69/197 (35%), Positives = 105/197 (53%), Gaps = 3/197 (1%) Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE--VKPAIKKQIIRELKVLHECNFAH 147 FE LG+G G V + K TG I+A K +H V+ I+KQ+ RE+++ + Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 148 IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHA 207 I+ YG F+ + I + +E+ G L L++A R E + + LSYL KH Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 208 Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSD 267 I HRD+KP NIL+ +GEIK+ DFG S + + GT Y+ PE ++G ++ + D Sbjct: 209 I-HRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVD 267 Query: 268 IWSLGLSLVEMAIGMYP 284 +WSLG+ E +G P Sbjct: 268 LWSLGVLTYEFLVGAPP 284 Score = 36.3 bits (80), Expect = 0.008 Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 1/40 (2%) Query: 332 KLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371 K+PS + D +D + R L+ NP++R L+ +M H WI K Sbjct: 304 KIPSFVPPDA-RDLISRLLQHNPEKRMSLEQVMRHPWIVK 342 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 121 bits (291), Expect = 2e-28 Identities = 84/279 (30%), Positives = 144/279 (51%), Gaps = 32/279 (11%) Query: 93 LGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR-ELKVLHECNFAHIVG 150 LG+ LG+G G V + + G +A K + L +I+ E+ +L + +IV Sbjct: 11 LGDCLGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVK 70 Query: 151 FYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMH 210 + G++ ++ + I +EY + GSL I K G+IPE+++ T VL+GL YL ++ ++H Sbjct: 71 YRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQ-GVIH 129 Query: 211 RDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWS 270 RD+K +NIL +G IK+ DFGV+ ++ +S VG+ +M+PE ++ + SDIWS Sbjct: 130 RDIKGANILTTKDGTIKLADFGVATKINALEDHSVVGSPYWMAPEVIELVGATTASDIWS 189 Query: 271 LGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPP 330 +G +++E+ G P D +A+F ++H P Sbjct: 190 VGCTVIELLDGNPPY--YDLDPTSALFRMVKDEHPP------------------------ 223 Query: 331 PKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369 LPS I S K F+ +C +K+P+ R + L+ H W+ Sbjct: 224 --LPSNI-SSAAKSFLMQCFQKDPNLRIKTRKLLKHPWV 259 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 120 bits (288), Expect = 5e-28 Identities = 83/280 (29%), Positives = 141/280 (50%), Gaps = 15/280 (5%) Query: 13 LPPGSIDTNPAA--TPSNMTP-QLKSATANERQGLAGKSKT---SIEALTERLEQIEMDD 66 L P ++ T+ P+N TP Q ++ T+ + + +A K S L +R + + +D Sbjct: 307 LTPQTLSTSETKHIRPNNSTPYQRRAETSTKPKAVATPQKVEAPSAPRLQKRAPRQQSND 366 Query: 67 TQRRRIEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVK 126 + +C + L + ++GQG G V R T L +A K +++ + Sbjct: 367 SAVLAKLQSICNPKNPTLL----YRNFVKIGQGASGDVYSARQVGTNLSVAIKKMNINQQ 422 Query: 127 PAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPES 186 P K+ I+ E+ V+ + +IV F F+ E+ + MEYM GGSL ++ + E Sbjct: 423 PK-KEFIVNEILVMKSHHHKNIVNFIDTFFYKSELWMVMEYMRGGSLTEVVTN-NTLSEG 480 Query: 187 ILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NS 244 + I L+GL +L + + I+HRD+K NIL++ G+IK+ DFG Q+ +M + Sbjct: 481 QIAAICKETLEGLQHLHE-NGIVHRDIKSDNILLSLQGDIKLTDFGFCAQIDSNMTKRTT 539 Query: 245 FVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 VGT +M+PE + Y + D+WSLG+ +EM G P Sbjct: 540 MVGTPYWMAPEVVTRKEYGFKVDVWSLGIMAIEMVEGEPP 579 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 118 bits (285), Expect = 1e-27 Identities = 90/289 (31%), Positives = 152/289 (52%), Gaps = 39/289 (13%) Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC---NFA 146 + KL +G+G+ G V + T +A K+++L+ I +E+ VL E + Sbjct: 10 YTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSDVE 69 Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206 +I+ ++G++ + I M+Y GGS+ +++ AG I E + I L+ L ++ H Sbjct: 70 NIIKYHGSYLVGTNLWIIMDYCHGGSVRTLME-AGPISEPCISLILRETLQALKFIH--H 126 Query: 207 A-IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQ-GTHY 262 A I+HRD+K +NILV+ +G +K+CDFGV+ +L + +F+GT +M+PE ++ G Y Sbjct: 127 AGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRDGQEY 186 Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELL 322 +V +DIWSLG++ E+A G PP AK ED F + Sbjct: 187 NVMADIWSLGITAYEIATG----SPPHAK----------EDP--------------FRAV 218 Query: 323 DYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371 I + PP+L +G FS K+F+ CL+ P R D L+ ++I++ Sbjct: 219 YLIAHTAPPRL-NGNFSALLKEFIASCLQDVPQRRLDSSELLKSKFIKQ 266 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 113 bits (273), Expect = 3e-26 Identities = 75/222 (33%), Positives = 125/222 (56%), Gaps = 19/222 (8%) Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQ-------IIRELKVLHECNFAHI 148 +G G+ G V + S+G +MA K + L+ K + + E+ +L E + HI Sbjct: 400 IGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSHEHI 459 Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208 V + G+ + ++I +EY+ GGS+ +L G E+++ LKGL YL + I Sbjct: 460 VQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSR-GI 518 Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQL-IDSMAN-------SFVGTRSYMSPERLQGT 260 +HRD+K +NILV++ G+IKI DFG+S +L ++S + SF G+ +M+PE ++ T Sbjct: 519 VHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVKQT 578 Query: 261 HYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFG-GQN 301 ++ ++DIWSLG ++EM +P P D + AIF G+N Sbjct: 579 MHTEKTDIWSLGCLVIEMLTSKHPYPNCD--QMQAIFRIGEN 618 >SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosaccharomyces pombe|chr 1|||Manual Length = 696 Score = 112 bits (270), Expect = 7e-26 Identities = 73/214 (34%), Positives = 111/214 (51%), Gaps = 9/214 (4%) Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH--LEVKPAIKKQIIRELKVLHECNF 145 +DF L +G+G G V VR T I A K I L V+ + E +L + Sbjct: 300 EDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTSL 359 Query: 146 AH---IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202 IVG +F + ++ + +YM GG L L+ GR PE + ++ L +L Sbjct: 360 DESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHL 419 Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPE-RLQG 259 KH I++RD+KP NIL++++G I +CDFG+S + + A N+F GT Y++PE L+ Sbjct: 420 H-KHDIIYRDLKPENILLDADGHIALCDFGLSKANLSANATTNTFCGTTEYLAPEVLLED 478 Query: 260 THYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTL 293 Y+ Q D WSLG+ + EM G P PD + + Sbjct: 479 KGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQM 512 Score = 27.1 bits (57), Expect = 4.7 Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 4/39 (10%) Query: 332 KLPSGIFSDEFKDFVDRCLKKNPDER----ADLKTLMNH 366 + P G+ S E + FV L +NP+ R AD L H Sbjct: 522 RFPKGVLSSEGRSFVRGLLNRNPNHRLGAVADTTELKEH 560 >SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|Schizosaccharomyces pombe|chr 3|||Manual Length = 288 Score = 111 bits (268), Expect = 1e-25 Identities = 62/199 (31%), Positives = 111/199 (55%), Gaps = 8/199 (4%) Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148 ++++L +LG+G V K +++ TG I+A K+I ++ IRE+ ++ E +I Sbjct: 2 NYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNI 61 Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLI--LKKAGRIPESILGTITSAVLKGLSYLRDKH 206 + ++ ++ + EYM+ + G +P S + T +LKG+S+ + Sbjct: 62 MSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHENR 121 Query: 207 AIMHRDVKPSNILVNSNGEIKICDFGVS---GQLIDSMANSFVGTRSYMSPERLQGTH-Y 262 ++HRD+KP N+L+NS GE+K+ DFG++ G +++ +N V T Y +P+ L G+ Y Sbjct: 122 -VLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVV-TLWYRAPDVLLGSRVY 179 Query: 263 SVQSDIWSLGLSLVEMAIG 281 S DIWS+G + EMA G Sbjct: 180 STSIDIWSVGCIMAEMATG 198 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 108 bits (259), Expect = 2e-24 Identities = 90/293 (30%), Positives = 146/293 (49%), Gaps = 41/293 (13%) Query: 94 GEL-GQGNGGVVMKVRHKSTGLIMARKLI---------HLEVKPAIKKQIIRELKVLHEC 143 GEL G G G V + +TG ++A K + H +++ I I E+ ++ + Sbjct: 828 GELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISMIADL 887 Query: 144 NFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLR 203 + +IV + G ++ +ISI +EY+ GGS+ L+ G E ++ ++ VL GLSYL Sbjct: 888 DHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSRQVLYGLSYLH 947 Query: 204 DKHAIMHRDVKPSNILVNSNGEIKICDFGV---SGQLIDSMAN-SFVGTRSYMSPERLQG 259 K I+HRD+K N+L++ +G KI DFG+ S + D+ AN S G+ +M+PE + Sbjct: 948 SK-GIIHRDLKADNLLIDFDGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHN 1006 Query: 260 TH--YSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMA 317 H YS + D+WSLG ++EM G P +A + A+F E +P P P Sbjct: 1007 DHQGYSAKVDVWSLGCVVLEMLAGRRPWSTDEA--IQAMFKLGTEKKAP------PIPS- 1057 Query: 318 IFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370 EL+ + S E F++ C N D R + L+NH +++ Sbjct: 1058 --ELVSQV-------------SPEAIQFLNACFTVNADVRPTAEELLNHPFMK 1095 >SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 436 Score = 104 bits (249), Expect = 3e-23 Identities = 65/216 (30%), Positives = 114/216 (52%), Gaps = 7/216 (3%) Query: 83 GELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH---LEVKPAIKKQIIRELKV 139 G++ DF+ L LG+G+ G V+ V+ K+TG + A+K + + ++ +Q E ++ Sbjct: 84 GKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQI 143 Query: 140 LHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGL 199 L E I Y AF + + ++Y GG L L + +PE ++ T+ + L Sbjct: 144 LEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLAL 203 Query: 200 SYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERL 257 +L K I++RD+KP N L+++ G I + DFG+S ++ ++ A+ SFVGT Y +PE L Sbjct: 204 IHLH-KLGIVYRDLKPENCLLDAEGHILLTDFGLS-KVAENGADCRSFVGTEEYCAPEIL 261 Query: 258 QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTL 293 Y D WS+G+ + ++ G P + K + Sbjct: 262 LEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRI 297 Score = 26.6 bits (56), Expect = 6.2 Identities = 11/32 (34%), Positives = 19/32 (59%), Gaps = 1/32 (3%) Query: 326 VNEPPPKLPSGIFSDEFKDFVDRCLKKNPDER 357 + P +P + SD +D +++ LKKNP +R Sbjct: 301 ITRAKPNIPFYVTSDA-RDIINKFLKKNPKQR 331 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 101 bits (243), Expect = 1e-22 Identities = 81/281 (28%), Positives = 134/281 (47%), Gaps = 15/281 (5%) Query: 13 LPPGSIDTNPAATPSNMTPQLKSATANERQGLA-GKSKTSIEALTER-LEQIEMD---DT 67 L P + + + + S + Q S G G+ +++++ L +R + ++ + D Sbjct: 121 LIPSPLPESASRSSSQSSHQRHSRDGRGELGSEHGERRSAMDGLRDRHIRKVRVSQLLDL 180 Query: 68 QRRRIE-VFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVK 126 QRRRI K++ G DF L LG G+ G V V+ L A K++ + K Sbjct: 181 QRRRIRPADHTTKDRYGI---QDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKK-K 236 Query: 127 PAIKKQIIR---ELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRI 183 KQI E +L I +G F + + M++ +GG L +L+K R Sbjct: 237 IVDMKQIEHTCDERYILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRF 296 Query: 184 PESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN 243 PE + + V+ L YL I++RD+KP N+L++ G +KI DFG + ++ S Sbjct: 297 PEKVAKFYAAEVILALDYLHHNQ-IVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCC 355 Query: 244 SFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 + GT Y++PE + Y+ +D WSLG+ + EM G YP Sbjct: 356 TLCGTPDYLAPEIISLKPYNKAADWWSLGILIFEMLAG-YP 395 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 100 bits (240), Expect = 3e-22 Identities = 63/192 (32%), Positives = 111/192 (57%), Gaps = 8/192 (4%) Query: 92 KLGELGQGNGGVVMKVRHKSTGLI--MARKLIHLEVKPAIKKQIIRELKVLHECNFAHIV 149 KLG+ G+ + V K G+ +A K I L+ + K+ I+ E+ V+ E +IV Sbjct: 314 KLGQGASGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTR-KELILNEITVMRESIHPNIV 372 Query: 150 GFYGAFY-SDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208 + +F + + + MEYM+ GSL I++K+ ++ E+ + I KG+ +L ++ I Sbjct: 373 TYLDSFLVRERHLWVVMEYMNAGSLTDIIEKS-KLTEAQIARICLETCKGIQHLHARN-I 430 Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGTHYSVQS 266 +HRD+K N+L++++G IKI DFG +L + + + VGT +M+PE ++ Y + Sbjct: 431 IHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRVTMVGTPYWMAPEVVKQNEYGTKV 490 Query: 267 DIWSLGLSLVEM 278 DIWSLG+ ++EM Sbjct: 491 DIWSLGIMIIEM 502 >SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizosaccharomyces pombe|chr 1|||Manual Length = 646 Score = 100 bits (240), Expect = 3e-22 Identities = 69/205 (33%), Positives = 104/205 (50%), Gaps = 9/205 (4%) Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKK--QIIRELKVLHECNF 145 DDF L +G+G G V VR K T + A K++ +V K+ + E +L + + Sbjct: 264 DDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSA 323 Query: 146 AH---IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202 A IV +F + ++ + +YM GG L L+K+ R PE + +L L L Sbjct: 324 ADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQAL 383 Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVS--GQLIDSMANSFVGTRSYMSPE-RLQG 259 K I++RD+KP NIL++ G I +CDFG+S + + +F GT Y++PE L Sbjct: 384 H-KRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTFCGTTDYLAPEVILDE 442 Query: 260 THYSVQSDIWSLGLSLVEMAIGMYP 284 Y + D WSLG+ L EM G P Sbjct: 443 AGYDMMVDFWSLGVLLYEMTCGWSP 467 >SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizosaccharomyces pombe|chr 3|||Manual Length = 569 Score = 99.5 bits (237), Expect = 7e-22 Identities = 67/205 (32%), Positives = 106/205 (51%), Gaps = 7/205 (3%) Query: 85 LSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLI---HLEVKPAIKKQIIRELKVLH 141 L+ D FE L +G+G+ G VM+VR + T I A K + H+ + + + E VL Sbjct: 225 LTIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVD-HTLAERTVLA 283 Query: 142 ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201 + N IV +F S G++ + + +++GG L L++ G + +L L Sbjct: 284 QVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALEC 343 Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVS--GQLIDSMANSFVGTRSYMSPERLQG 259 L + + I +RD+KP NIL++ G I +CDFG+ N+F GT Y++PE L G Sbjct: 344 LHEFNVI-YRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLG 402 Query: 260 THYSVQSDIWSLGLSLVEMAIGMYP 284 Y+ D W+LG+ L EM G+ P Sbjct: 403 HGYTKVVDWWTLGVLLYEMITGLPP 427 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 99.1 bits (236), Expect = 1e-21 Identities = 70/237 (29%), Positives = 124/237 (52%), Gaps = 19/237 (8%) Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE-VKPAIKKQIIRELKVLHEC--- 143 ++++K+ ++G+G GVV K RHK +G I+A K I LE + IRE+ +L E Sbjct: 2 ENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDE 61 Query: 144 -NFAHIVGFYGAFYSDGEISICMEYMD---GGSLDLILKK-AGRIPESILGTITSAVLKG 198 N ++ V +++ ++ + E++D +D I + A + ++ T ++ G Sbjct: 62 NNRSNCVRLLDILHAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNG 121 Query: 199 LSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPER 256 +++ + I+HRD+KP N+L++ G +K+ DFG++ + N + T Y +PE Sbjct: 122 VNFCHSRR-IIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIVTLWYRAPEV 180 Query: 257 LQGT-HYSVQSDIWSLGLSLVEMAIGMYPIPPPDAK-----TLAAIFGGQNEDHSPG 307 L G+ HYS DIWS+G EM I P+ P D++ + + G NE+ PG Sbjct: 181 LLGSRHYSTGVDIWSVGCIFAEM-IRRSPLFPGDSEIDEIFKIFQVLGTPNEEVWPG 236 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 99.1 bits (236), Expect = 1e-21 Identities = 63/202 (31%), Positives = 101/202 (50%), Gaps = 5/202 (2%) Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMA-RKLIHLEVKPAIKKQIIRELKVLHECNFAHI 148 + L +G G G+V + + TG+ +A +K++ P + K+ RELK+L +I Sbjct: 20 YSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENI 79 Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208 + F S E + + G L +L + + +L+GL ++ + Sbjct: 80 ISLSDIFISPFEDIYFVTELLGTDLHRLLTSRP-LETQFIQYFLYQILRGLKFVHSA-GV 137 Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPE-RLQGTHYSVQSD 267 +HRD+KPSNIL+N N ++KICDFG++ ++ D +V TR Y +PE L Y+V+ D Sbjct: 138 IHRDLKPSNILINENCDLKICDFGLA-RIQDPQMTGYVSTRYYRAPEIMLTWQKYNVEVD 196 Query: 268 IWSLGLSLVEMAIGMYPIPPPD 289 IWS G EM G P D Sbjct: 197 IWSAGCIFAEMIEGKPLFPGRD 218 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 96.7 bits (230), Expect = 5e-21 Identities = 60/197 (30%), Positives = 99/197 (50%), Gaps = 6/197 (3%) Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEV-KPAIKKQIIRELKVLHECNFAHI 148 +EK+ ++G+G G V K + TG ++A K I LE K +RE+K+L +I Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNI 336 Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208 V + + EYMD ++L + ++ + + L+YL + + Sbjct: 337 VRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLHHR-GV 395 Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSF---VGTRSYMSPERLQG-THYSV 264 +HRD+K SNIL+N+NG++K DFG++ S + ++ V T + PE L G T Y Sbjct: 396 LHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGETAYDT 455 Query: 265 QSDIWSLGLSLVEMAIG 281 DIWS G ++E+ G Sbjct: 456 AVDIWSAGCIVMELFTG 472 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 94.3 bits (224), Expect = 3e-20 Identities = 60/194 (30%), Positives = 100/194 (51%), Gaps = 8/194 (4%) Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIH---LEVKPAIKKQIIRELKVLHECNFAHIVGFY 152 LGQGN V +H T +A K+++ LE K K+ + RE+ +L + + +I+ Y Sbjct: 29 LGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKR-LQREVTILRQLHHPNIITLY 87 Query: 153 GAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRD 212 F + +EYMD +++K R+ E I ++ + Y H + HRD Sbjct: 88 QVFRVPKYTVLALEYMDTDLHSMVVKH-NRLDECTTRKIFRQIVHAIDYCH-LHRVAHRD 145 Query: 213 VKPSNILVNSNGEIKICDFGVSGQLID-SMANSFVGTRSYMSPERLQGTHY-SVQSDIWS 270 +K NIL+N + +K+ DFG+S ++D S ++ GT Y +PE +QG +Y D+W Sbjct: 146 LKLENILLNKDLVVKLTDFGLSNFMLDGSFLSTSCGTPHYAAPEVIQGRYYDGCDVDVWG 205 Query: 271 LGLSLVEMAIGMYP 284 G+ L M +G +P Sbjct: 206 CGILLYLMLVGEFP 219 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 93.5 bits (222), Expect = 5e-20 Identities = 88/298 (29%), Positives = 130/298 (43%), Gaps = 30/298 (10%) Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKK---QIIRELKVLHECNFA 146 F + G G GV M+ TG ++A K I L+ + QI E+ VL N Sbjct: 1042 FVRSGMFGDVYTGVNME-----TGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLERLNHP 1096 Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRI-PESILGTITSAVLKGLSYLRDK 205 ++V +YG ++ I ME+ GGSL +L GRI E++L +L+GL+Y+ + Sbjct: 1097 NVVTYYGVEVHREKVYIFMEFCQGGSLADLLAH-GRIEDENVLKVYVVQLLEGLAYIHSQ 1155 Query: 206 HAIMHRDVKPSNILVNSNGEIKICDFG------------VSGQLIDSMANSFVGTRSYMS 253 H I+HRD+KP+NIL++ G IK DFG V + I GT YM+ Sbjct: 1156 H-ILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMYMA 1214 Query: 254 PERLQGTHYS--VQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPN 311 PE + GT DIWSLG ++EM G P D + AI H+P N Sbjct: 1215 PEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPWSEMDNEW--AIMYHVAAMHTPSIPQN 1272 Query: 312 SPRPMAIFELLDYIVNEPPPKLPSGI---FSDEFKDFVDRCLKKNPDERADLKTLMNH 366 + ++ P + P + DF + + P KT ++H Sbjct: 1273 EKISSLARDFIEQCFERDPEQRPRAVDLLTHPWITDFRKKTIITMPPATITKKTSLSH 1330 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 93.5 bits (222), Expect = 5e-20 Identities = 58/193 (30%), Positives = 98/193 (50%), Gaps = 6/193 (3%) Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEV--KPAIKKQIIRELKVLHECNFAHIVGFYG 153 LG+G+ G V H T +A K I ++ K + ++ RE+ L HI+ Y Sbjct: 40 LGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPHIIKLYD 99 Query: 154 AFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDV 213 + +I + +EY G D I++K R+ E ++ + Y +H I+HRD+ Sbjct: 100 VITTPTDIVMVIEYAGGELFDYIVEKK-RMTEDEGRRFFQQIICAIEYCH-RHKIVHRDL 157 Query: 214 KPSNILVNSNGEIKICDFGVSGQLID-SMANSFVGTRSYMSPERLQGTHYS-VQSDIWSL 271 KP N+L++ N +KI DFG+S + D + + G+ +Y +PE + G Y+ + D+WS Sbjct: 158 KPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSC 217 Query: 272 GLSLVEMAIGMYP 284 G+ L M +G P Sbjct: 218 GIVLYVMLVGRLP 230 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 92.3 bits (219), Expect = 1e-19 Identities = 65/210 (30%), Positives = 109/210 (51%), Gaps = 17/210 (8%) Query: 87 DDDFEKLGELGQGNGGVVMKVRH---KSTGLIMARKLIHLEVKPAIKKQIIRELKVL-HE 142 + +F+ + ELGQG G+V R+ K + +K+ ++ K + K+ +RE+K+L H Sbjct: 18 EPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIHF 77 Query: 143 CNFAHIVGFYGAF----YSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKG 198 N +I Y Y+ E+ I E M+ L+ I+K + ++ + +L G Sbjct: 78 RNHRNITCIYDLDIINPYNFNEVYIYEELMEA-DLNAIIKSGQPLTDAHFQSFIYQILCG 136 Query: 199 LSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS------MANSFVGTRSYM 252 L Y+ + I HRD+KP N+LVN++ E+KICDFG++ ++ +V TR Y Sbjct: 137 LKYIHSANVI-HRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGFMTEYVATRWYR 195 Query: 253 SPE-RLQGTHYSVQSDIWSLGLSLVEMAIG 281 +PE L + Y D+WS+G L E+ G Sbjct: 196 APEIMLSFSSYHKGIDVWSVGCILAELLGG 225 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 89.8 bits (213), Expect = 6e-19 Identities = 86/306 (28%), Positives = 135/306 (44%), Gaps = 44/306 (14%) Query: 78 QKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTG------LIMARKLIHLEVKPAIKK 131 QK I + + +E + LG G VV ++G +I RK++ + + Sbjct: 156 QKNMI-KSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATE 214 Query: 132 QIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTI 191 RE+ +L + +V + F +D E+ I MEY++GG L L G I E + Sbjct: 215 MFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPL 274 Query: 192 TSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL--IDSMANSFVGTR 249 +L+ L +L K + HRD+KP NIL+ ++ +KI DFG++ + + +F GT Sbjct: 275 LKQLLETLLHLH-KQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTM 333 Query: 250 SYMSPERLQGTH------YSVQSDIWSLGLSLVEMAIGMYPI-PPPDAKTLAAIFGGQNE 302 Y++PE L+ + Y + DIWSLG L M P AK + I Sbjct: 334 GYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELI------ 387 Query: 303 DHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKT 362 S G P P LL+ NE S+E D ++R L+ NP++R Sbjct: 388 --SKGAYPIEP-------LLE---NE---------ISEEGIDLINRMLEINPEKRISESE 426 Query: 363 LMNHEW 368 + H W Sbjct: 427 ALQHPW 432 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 89.0 bits (211), Expect = 1e-18 Identities = 62/209 (29%), Positives = 100/209 (47%), Gaps = 10/209 (4%) Query: 86 SDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIK-KQIIRELKVLHECN 144 S F+ +G+G+ V V+H+ T A K I+ + K K++ E+ +L N Sbjct: 26 SVSQFKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKKKHDEHKIKKLRNEVLLLQSLN 85 Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRD 204 + FY F + +I + + M GG L + + + ES++ ++ L Y+ Sbjct: 86 HPLLCKFYSEFEDETKIYLVTDLMLGGDLRYHISQR-KFNESVIRIWMVELVSALIYIHS 144 Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS-------MANSFVGTRSYMSPERL 257 K ++HRDVKP NIL++ G K+ DF V+ ++ S M VGT YM+PE L Sbjct: 145 K-GVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSNMTVGRVGTPVYMAPETL 203 Query: 258 QGTHYSVQSDIWSLGLSLVEMAIGMYPIP 286 +SD WSLG++ E + P P Sbjct: 204 IHAVSYKESDWWSLGITFYECLFQVRPFP 232 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 88.2 bits (209), Expect = 2e-18 Identities = 81/298 (27%), Positives = 134/298 (44%), Gaps = 23/298 (7%) Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147 +++E + +GQG GVV HK +GL +A K IH P + +RE+K+L + Sbjct: 37 EEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHPFNHPVFCLRTLREIKLLRHFRHEN 96 Query: 148 IVGFYGAF----YSDGE-ISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202 I+ Y + E + I E M+ +I ++ + + T +L+ L + Sbjct: 97 IISILDILPPPSYQELEDVYIVQELMETDLYRVI--RSQPLSDDHCQYFTYQILRALKAM 154 Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN-----SFVGTRSYMSPE-R 256 ++HRD+KPSN+L+N+N ++K+ DFG++ N +V TR Y +PE Sbjct: 155 HSA-GVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATRWYRAPEIM 213 Query: 257 LQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPM 316 L YS D+WS G L EM P D + + N +P S Sbjct: 214 LSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLI--LNILGTPTMDDFSRIKS 271 Query: 317 AIFELLDYIVNEP-PPKLP-SGIF---SDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369 A YI + P PK+ +F S + D +++ L NPD+R + + H ++ Sbjct: 272 A--RARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEEALKHPYV 327 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 88.2 bits (209), Expect = 2e-18 Identities = 62/212 (29%), Positives = 104/212 (49%), Gaps = 5/212 (2%) Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHL-EVKPAIKKQIIRELKVLHECNFAHI 148 + K ++G+G VV R K T +A K I + + K I +RE+K L E ++ Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHDNV 70 Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAI 208 + F + ++I +E++D LI K + + + +L+GL ++ + I Sbjct: 71 IELVDVFSTKSNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSRF-I 129 Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQL-IDSMANSFVGTRSYMSPERLQGTH-YSVQS 266 +HRD+KP+N+L++S+G +K+ DFG+S S + V TR Y PE G Y Sbjct: 130 LHRDLKPNNLLISSDGVLKLADFGLSRDFGTPSHMSHQVITRWYRPPELFMGCRSYGTGV 189 Query: 267 DIWSLGLSLVEMAIGMYPIP-PPDAKTLAAIF 297 D+WS+G E+ + +P D L IF Sbjct: 190 DMWSVGCIFAELMLRTPYLPGESDLDQLNVIF 221 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 87.0 bits (206), Expect = 4e-18 Identities = 81/288 (28%), Positives = 133/288 (46%), Gaps = 17/288 (5%) Query: 94 GELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELK----VLHECNFAHIV 149 G +G G+ G V + + TG +MA K + L KP I + +I+ +K VL + ++V Sbjct: 1124 GLIGSGSFGTVYRAVNLDTGDLMAVKEVALH-KPRISRPMIKRIKGEMLVLELFDHPNVV 1182 Query: 150 GFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIP-ESILGTITSAVLKGLSYLRDKHAI 208 +YG +++I ME G SL L+ GRI E ++ +L+GL+Y+ + Sbjct: 1183 SYYGIEVHREKVNIFMELCQGSSLFEFLRY-GRIEDELVIQVYVLQLLEGLAYIHSC-GV 1240 Query: 209 MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDI 268 H+DVKP NIL + NG +K DFG S ++ S + + E + +Q Sbjct: 1241 SHQDVKPENILFDHNGIMKFTDFG-SAKMSGSASTKIFEQLTQQEEEEFEKDSEFLQHLD 1299 Query: 269 WSLGLSLVEMAIGMYP---IPPPDAKTLAA---IFGGQNEDHSPGQAPNSPRPMAIFELL 322 + G SL M P + P + A G + + G +P PR F L+ Sbjct: 1300 QNRGYSLTGTPTYMAPELILGNPSERVGAMDIWSLGCVIVEMATG-SPPWPRLDNHFSLM 1358 Query: 323 DYIVNEPPPKLPS-GIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369 +I PP +P+ S ++F+ RC +P++RA L+ W+ Sbjct: 1359 YHIAAHNPPIIPADDQLSPLGQNFLKRCFVSDPNQRATAAELLMDPWV 1406 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 86.6 bits (205), Expect = 6e-18 Identities = 60/202 (29%), Positives = 99/202 (49%), Gaps = 8/202 (3%) Query: 99 GNGGVVMKVRHKST-GLIMARKLIHLEV--KPAIKKQIIRELKVLHECNFAHIVGFYGAF 155 G GG R K G I A K+I K ++ E+KV + +IVGF F Sbjct: 48 GEGGFARCFRVKDNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMSHPNIVGFIDCF 107 Query: 156 YSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKP 215 I + +E + SL +L+K ++ E + + +L L Y+ K I HRD+K Sbjct: 108 EDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVI-HRDLKL 166 Query: 216 SNILVNSNGEIKICDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTH--YSVQSDIWSL 271 NI+++ + +KI DFG++ L+D + GT +Y++PE L + +S + D+WS Sbjct: 167 GNIMLDESNNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGHSFEVDLWSA 226 Query: 272 GLSLVEMAIGMYPIPPPDAKTL 293 G+ + + IG P + KT+ Sbjct: 227 GVVMYALLIGKPPFQDKEVKTI 248 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 86.2 bits (204), Expect = 7e-18 Identities = 64/217 (29%), Positives = 110/217 (50%), Gaps = 13/217 (5%) Query: 83 GELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE 142 GE +E LG G+ GVV++ + T +A K + L+ K K + ++ ++ + Sbjct: 18 GEKKTISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRV-LQDK-RYKNRELQIMRAISH 75 Query: 143 CNFAHIVGFYGAFY-SDGEISICM--EYMDGGSLDLI---LKKAGRIPESILGTITSAVL 196 N ++ F+ S E +C+ EYM D + ++ IP + + Sbjct: 76 PNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLF 135 Query: 197 KGLSYLRDKHAIMHRDVKPSNILVN-SNGEIKICDFGVSGQLIDSMAN-SFVGTRSYMSP 254 + L+YL + HRD+KP N+LV+ G +K+CDFG + L+ S N S++ +R Y +P Sbjct: 136 RALAYLHST-GVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSEPNVSYICSRYYRAP 194 Query: 255 ERLQG-THYSVQSDIWSLGLSLVEMAIGMYPIPPPDA 290 E + G THY+ + D+WS + E+ IG P+ P D+ Sbjct: 195 ELVFGATHYTTKIDVWSAACVIAELFIGR-PLFPGDS 230 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 85.8 bits (203), Expect = 1e-17 Identities = 52/160 (32%), Positives = 85/160 (53%), Gaps = 11/160 (6%) Query: 129 IKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLI----LKKAGRIP 184 + + IRE+ + E +IV DG IS+ EY + L +I + +IP Sbjct: 54 VSQSAIREMMLCREIQHENIVSLVQVLLKDGTISMVFEYAEHDLLQIIHFHSRSRTRQIP 113 Query: 185 ESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM--- 241 SIL +I ++ G++YL + IMHRD+KP+NI++ + G++KI D G+ + D + Sbjct: 114 PSILKSILWQIINGVAYLHENW-IMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPF 172 Query: 242 --ANSFVGTRSYMSPERLQGTH-YSVQSDIWSLGLSLVEM 278 ++ V T Y +PE L G H Y+ D+W++G EM Sbjct: 173 YSSDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEM 212 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 85.4 bits (202), Expect = 1e-17 Identities = 60/225 (26%), Positives = 108/225 (48%), Gaps = 13/225 (5%) Query: 78 QKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIREL 137 ++EK ++ DDF L LG+GN G VM +K A K++ E +K + + L Sbjct: 652 RREKKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEA--ILKNEELESL 709 Query: 138 K-------VLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGT 190 K V ++ ++ + +F + + MEY+ GG L + +++ + Sbjct: 710 KTEKHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQ-QFSVKRARF 768 Query: 191 ITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGV--SGQLIDSMANSFVGT 248 + V L Y + + I +RD+K NIL+ +G I+I D+G+ L+ + ++F GT Sbjct: 769 YGAEVCLALKYFHE-NGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGNTTSTFCGT 827 Query: 249 RSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTL 293 +M+PE L YS D W+ G+ + +M +G P D + + Sbjct: 828 PEFMAPEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEI 872 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 85.0 bits (201), Expect = 2e-17 Identities = 59/203 (29%), Positives = 96/203 (47%), Gaps = 7/203 (3%) Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLI--HLEVKPAIKKQIIRELKVLHECNFAHIVGFYG 153 LG G +H+ TG + K I E+ + + +I EL +L +++ Sbjct: 16 LGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPNVLQLID 75 Query: 154 AFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRD 212 + ++ + +EYM GG L D +L+K G E +L GL Y H I HRD Sbjct: 76 VISAQEQLFVVVEYMPGGELFDCMLRK-GSFTEQDTAKFLWQILCGLEYCHKLH-ICHRD 133 Query: 213 VKPSNILVNSNGEIKICDFGVSG-QLIDSMANSFVGTRSYMSPERLQGTHY-SVQSDIWS 270 +KP N+ ++++G IKI +FG++ Q + + G+ Y SPE + G Y SDIWS Sbjct: 134 LKPENLYLDAHGSIKIGEFGMASIQQPGKLLQTSCGSPHYASPEIIMGRSYDGCASDIWS 193 Query: 271 LGLSLVEMAIGMYPIPPPDAKTL 293 G+ + G P + ++L Sbjct: 194 CGIIFFALLTGKLPFDDDNIRSL 216 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 84.6 bits (200), Expect = 2e-17 Identities = 61/217 (28%), Positives = 108/217 (49%), Gaps = 29/217 (13%) Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHL-EVKPAIKKQIIRELKVLHECNFAHIVGFYGA 154 +G G+ G + KV+ G ++A+K IH + K+ I E+ +L +IV + G Sbjct: 10 IGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYIADEVNILRNLKHPNIVQYCGE 69 Query: 155 FYSDGE--ISICMEYMDGGSLDLILKK----AGRIPESILGTITSAVLKGL--------- 199 + I++ MEY G L ++++ R E + + +L L Sbjct: 70 ELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALYRCHYGENA 129 Query: 200 ---------SYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS---MANSFVG 247 K +++HRD+KP+NI ++ N +K+ DFG+S +L+D+ S+VG Sbjct: 130 PACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLS-KLLDNTRVFTQSYVG 188 Query: 248 TRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 T YMSPE ++ + YS +SD+W+LG + E+ + +P Sbjct: 189 TPYYMSPEIIRSSPYSAKSDVWALGCVIFEICMLTHP 225 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 83.4 bits (197), Expect = 5e-17 Identities = 77/305 (25%), Positives = 140/305 (45%), Gaps = 33/305 (10%) Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH----LEVKPAIKKQIIRELKVLHECNF 145 +E + LG+G+ G V++ TG ++A K+I ++ ++ +I+++++ + Sbjct: 699 YEVVDFLGKGSFGQVLRCIDYETGKLVALKIIRNKKRFHMQALVETKILQKIREWDPLDE 758 Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRD 204 +V + FY + + E + +LI + +P ++ +IT +++ L+ L + Sbjct: 759 YCMVQYTDHFYFRDHLCVATELLGKNLYELIKSNGFKGLPIVVIKSITRQLIQCLTLLNE 818 Query: 205 KHAIMHRDVKPSNILVNS--NGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY 262 KH I H D+KP NIL+ ++K+ DFG S +++ +R Y SPE + G Y Sbjct: 819 KHVI-HCDLKPENILLCHPFKSQVKVIDFG-SSCFEGECVYTYIQSRFYRSPEVILGMGY 876 Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAK-----TLAAIFGGQNEDHSP----------G 307 D+WSLG + EM G +P+ P + + + IFG DHS Sbjct: 877 GTPIDVWSLGCIIAEMYTG-FPLFPGENEQEQLACIMEIFG--PPDHSLIDKCSRKKVFF 933 Query: 308 QAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDE---FKDFVDRCLKKNPDERADLKTLM 364 + PRP F + P K + + F F+ CLK +PDER + Sbjct: 934 DSSGKPRP---FVSSKGVSRRPFSKSLHQVLQCKDVSFLSFISDCLKWDPDERMTPQQAA 990 Query: 365 NHEWI 369 H+++ Sbjct: 991 QHDFL 995 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 82.2 bits (194), Expect = 1e-16 Identities = 68/256 (26%), Positives = 117/256 (45%), Gaps = 14/256 (5%) Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEV-----KPAIKKQIIRELKVLHE 142 +DF L LG+GN G VM KS + A K++ E + K R V + Sbjct: 681 EDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANR 740 Query: 143 CNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202 +V + F ++ I M+++ GG L L +++ + + V L Y Sbjct: 741 ERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE-QFSRRRAQFYAAEVCLALKYF 799 Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLI--DSMANSFVGTRSYMSPERLQGT 260 D + I++RD+K NIL++ +G +K+ D+G+ + + D+ +F GT +M+PE L Sbjct: 800 HD-NGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDNTTATFCGTPEFMAPEILLEQ 858 Query: 261 HYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFE 320 Y+ D W+ G+ + +M +G P D + IF D P + PR ++ Sbjct: 859 QYTRSVDWWAFGVLIYQMLLGQSPFRGEDEE---EIFDAILSD-EPLYPIHMPRD-SVSI 913 Query: 321 LLDYIVNEPPPKLPSG 336 L + +P +L SG Sbjct: 914 LQQLLTRDPKKRLGSG 929 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 82.2 bits (194), Expect = 1e-16 Identities = 58/199 (29%), Positives = 99/199 (49%), Gaps = 7/199 (3%) Query: 86 SDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKP-AIKKQIIRELKVLHECN 144 S DD+E L ++ +G+ G+V + KST ++A K I + +RE++ L Sbjct: 70 SIDDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIR 129 Query: 145 FAHIVGFYGAFYSDG--EISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202 +IV ++ + ME+M+ L+ +S + T+ +L +++ Sbjct: 130 HDNIVELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAFM 189 Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLID--SMANSFVGTRSYMSPERLQGT 260 H +HRD+KPSN+L+N+ GEIK+ DFG++ + + S V T Y +PE L G Sbjct: 190 HH-HWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGA 248 Query: 261 -HYSVQSDIWSLGLSLVEM 278 Y + D+WS+G EM Sbjct: 249 PSYGKEIDMWSIGCIFAEM 267 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 81.4 bits (192), Expect = 2e-16 Identities = 92/337 (27%), Positives = 145/337 (43%), Gaps = 37/337 (10%) Query: 62 IEMDDTQRRRIEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARK-- 119 +E + + RR+++V + + +G D+ + +LG+G G V K + + G + A K Sbjct: 9 VEDEKSARRKLDV-VPKLHFVGCSHLTDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRI 67 Query: 120 LIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYG--AFYSD------GEISICMEYMDGG 171 L+H E K IRE+K+L +I+ +D G I + YMD Sbjct: 68 LMHTE-KEGFPITAIREIKILKSIKHENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHD 126 Query: 172 SLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDF 231 L+ + + E + + G YL D+ I+HRD+K +N+L++++G +KI DF Sbjct: 127 LSGLLENPSVKFTEPQIKCYMKQLFAGTKYLHDQ-LILHRDLKAANLLIDNHGILKIADF 185 Query: 232 GVSGQLI-DSMANSFVG--------------TRSYMSPERLQG-THYSVQSDIWSLGLSL 275 G++ + +S AN G TR Y SPE L G Y+ D+WS+G + Sbjct: 186 GLARVITEESYANKNPGLPPPNRREYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIM 245 Query: 276 VEMAIGMYPI--PPPDAKTLAAIFGGQNEDHSPGQA--PNSPRPMAIFELLDYIVNEPPP 331 EM G PI D L IF SP QA PN + + + + Sbjct: 246 AEMYKGR-PILQGSSDLDQLDKIF---RLCGSPTQATMPNWEKLPGCEGVRSFPSHPRTL 301 Query: 332 KLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEW 368 + F E L NPDER + HE+ Sbjct: 302 ETAFFTFGKEMTSLCGAILTLNPDERLSASMALEHEY 338 >SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|Schizosaccharomyces pombe|chr 3|||Manual Length = 624 Score = 79.8 bits (188), Expect = 6e-16 Identities = 47/164 (28%), Positives = 82/164 (50%), Gaps = 3/164 (1%) Query: 79 KEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIK--KQIIRE 136 ++K ++ F+ L +LGQG G V + ++T ++A K++ + K I+ E Sbjct: 151 RKKRTKIQCSHFDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNE 210 Query: 137 LKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVL 196 +L N +V Y AF ++ + MEY+ GG L G + E+ + ++ Sbjct: 211 RDILTNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMV 270 Query: 197 KGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS 240 +S + K MHRD+KP N L++ G IK+ DFG+S ++ S Sbjct: 271 AAISAVH-KLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAIVTS 313 Score = 39.1 bits (87), Expect = 0.001 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Query: 239 DSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 ++ NS VG+ YM+PE + G Y D WSLG E +G YP Sbjct: 351 ENKVNSVVGSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVG-YP 395 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 79.4 bits (187), Expect = 8e-16 Identities = 56/176 (31%), Positives = 88/176 (50%), Gaps = 5/176 (2%) Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE--VKPAIKKQIIRELKVLH 141 E+ FEK+ LG+G+ G V VR K +G A K++ + +K K+ E +L Sbjct: 189 EVGPSSFEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILA 248 Query: 142 ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLIL-KKAGR-IPESILGTITSAVLKGL 199 N IV Y +F SD + +CMEY GG L ++ GR + E+ + V L Sbjct: 249 TSNHPFIVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAAL 308 Query: 200 SYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPE 255 YL ++RD+KP NIL++ +G I + DF +S Q + A + + R+ S + Sbjct: 309 EYLH-LMGFIYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQ 363 >SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase Cmk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 335 Score = 79.0 bits (186), Expect = 1e-15 Identities = 74/284 (26%), Positives = 122/284 (42%), Gaps = 39/284 (13%) Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH--IVGFYG 153 LG G V + H T + A K+++ ++ + + E+ +L ++ H I+ Sbjct: 37 LGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKRVSYEHPNILHLVD 96 Query: 154 AFYSDGEISICMEYMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRD 212 F + + + E GG L D I K G E+ + + YL D + I+HRD Sbjct: 97 FFETVNNLYLITELATGGELFDRICAK-GSFYEADAAALMRTTTSAVKYLHD-NGIVHRD 154 Query: 213 VKPSNILVNS---NGEIKICDFGVSGQLIDS---MANSFVGTRSYMSPERLQGTHYSVQS 266 +KP N+L S N ++ I DFG+S DS M + GT YM+PE + T Y Sbjct: 155 LKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPEYMAPEVFRRTGYGKPV 214 Query: 267 DIWSLGLSLVEMAIGMYPIP-PPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYI 325 D+W++G+ + G P P + + AI +Y Sbjct: 215 DMWAIGVITYFLLSGYTPFARPSQVEVIEAILAN-----------------------EYT 251 Query: 326 VNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369 N+P SGI S+ KDF+ +CL+ +P +R + H ++ Sbjct: 252 FNDP---CWSGI-SETAKDFIKKCLENDPSKRLTAADALKHPFL 291 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 79.0 bits (186), Expect = 1e-15 Identities = 72/308 (23%), Positives = 144/308 (46%), Gaps = 25/308 (8%) Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVK----PAIKKQIIRELKVLHECNF 145 +E + +G+G+ G V+K G ++A K+I K ++ I++ L + Sbjct: 518 YEIIDTVGKGSFGQVLKCIDHKRGQVVAIKVIKNRQKFHGQTLVEVGILKRLCEADPADK 577 Query: 146 AHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRD 204 +++ + F G + I E + D+I + + +P ++ + L+ L L+ Sbjct: 578 NNVIRYLSHFDFRGHLCIVTELLGSNLFDVIRENNYKGLPLIVVKSFALQGLQALRLLQG 637 Query: 205 KHAIMHRDVKPSNILVNS--NGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY 262 ++ I+H D+KP N+L++ IK+ DFG S + +++ +R Y +PE + G Y Sbjct: 638 QN-IIHCDLKPENLLLSHPLKARIKLIDFG-SSCFYNEKVYTYLQSRFYRAPEIILGLEY 695 Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAKT-----LAAIFGG------QNEDHSPGQAPN 311 + DIWS G L E+ G+ P+ P +T + + G +N S + Sbjct: 696 GKEIDIWSFGCILAELFTGV-PLFPGGNETEQLGYIMEVLGPPPMALIRNSTRSKAYFDS 754 Query: 312 SPRPMAIFELLDYIVNEPPPKLPSGIFSDE---FKDFVDRCLKKNPDERADLKTLMNHEW 368 +P I + + ++ P + S + + + F DF+ +CLK +P +R + + + HE+ Sbjct: 755 EGKPHPITDSHNRLL-VPSTRTFSQLLNTKQASFLDFLSKCLKWDPKDRITVDSALQHEF 813 Query: 369 IRKAEAEK 376 I ++K Sbjct: 814 ILGKTSQK 821 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 78.6 bits (185), Expect = 1e-15 Identities = 45/150 (30%), Positives = 82/150 (54%), Gaps = 4/150 (2%) Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKK--QIIRELKVLHECNF 145 D+F L E+ +G G V + +S+G A K+I ++KK ++ E + +H + Sbjct: 526 DEFILLKEINRGAYGRVYLAKKRSSGKYFALKMIPKSSLDSLKKIKGLLLEKRNMHIQRY 585 Query: 146 A-HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRD 204 + V Y AF S + + M+Y +GG + +++K G +PE + + +L + L Sbjct: 586 GPNTVKLYYAFDSGDYLCLVMDYFNGGDCETLIQKLGPLPEQWVCQYAAELLNAIELLH- 644 Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFGVS 234 + I+H D+KP+N+LV+ G I++ DFG+S Sbjct: 645 QDGIIHHDIKPANMLVDETGHIRLTDFGLS 674 Score = 36.3 bits (80), Expect = 0.008 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 4/51 (7%) Query: 247 GTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIF 297 GT +YM+PE L G + DIW++G + EM G P +A T+ AI+ Sbjct: 779 GTPNYMAPEILMGVD-TQMGDIWAMGCVIFEMLTGTRPF---EANTVKAIW 825 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 77.8 bits (183), Expect = 3e-15 Identities = 54/156 (34%), Positives = 80/156 (51%), Gaps = 6/156 (3%) Query: 83 GELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR---ELKV 139 G S D+E + + +G G V R +TG I A K++ +V K Q+ E V Sbjct: 557 GTPSIQDYEIIKPISKGTFGTVYLSRKNTTGEIYAIKVLR-KVDMISKNQVANVKAERAV 615 Query: 140 LH-ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKG 198 L + A + Y AF S + + ME+M+GG +LK IPES + V G Sbjct: 616 LMAQEESAFVAKLYYAFQSRDYLYLVMEFMNGGDCASLLKSLYTIPESWAKIYIAEVALG 675 Query: 199 LSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVS 234 L +L + I+HRD+KP NIL++ G +K+ DFG+S Sbjct: 676 LEHLH-RLGIIHRDIKPDNILMSITGHLKLADFGLS 710 Score = 38.7 bits (86), Expect = 0.001 Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 3/53 (5%) Query: 245 FVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIF 297 FVGT Y++PE L+G+ D W+LG L E G PP A+T +F Sbjct: 831 FVGTPDYLAPETLRGSTQDDMVDWWALGCVLFEFLFG---YPPFHAETPEKVF 880 >SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizosaccharomyces pombe|chr 1|||Manual Length = 534 Score = 77.8 bits (183), Expect = 3e-15 Identities = 60/209 (28%), Positives = 105/209 (50%), Gaps = 15/209 (7%) Query: 93 LGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA------ 146 L LG G G V + + T I+A K+I + KPA Q + E+ +L N Sbjct: 133 LDTLGHGTFGQVARCQDLKTQQIVAIKVI--KNKPAFYNQCVMEVSILELLNNKYDPEDK 190 Query: 147 -HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRD 204 H++ Y F + + E + +LI + R + S++ + + +L S L+ Sbjct: 191 RHLIRLYDQFMHKNHLCLVFELLSINLYELIKQNQFRGLHLSLVRSFATQLLSCTSLLKQ 250 Query: 205 KHAIMHRDVKPSNILVN--SNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY 262 I+H D+KP NIL+ S+ +K+ DFG + ++ +++ +R Y SPE + G HY Sbjct: 251 AR-IIHCDLKPENILLQDLSSPIVKVIDFGSACHERQTVY-TYIQSRFYRSPEVILGLHY 308 Query: 263 SVQSDIWSLGLSLVEMAIGMYPIPPPDAK 291 + D+WSLG L E+ +G+ P+ P +++ Sbjct: 309 NCGIDMWSLGCILAELFLGL-PLFPGNSE 336 >SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schizosaccharomyces pombe|chr 2|||Manual Length = 526 Score = 75.8 bits (178), Expect = 1e-14 Identities = 49/155 (31%), Positives = 78/155 (50%), Gaps = 5/155 (3%) Query: 84 ELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE--VKPAIKKQIIRELKVLH 141 E++ FEK+ LGQG+ G V VR KS + A K+++ +K +++ E ++L Sbjct: 149 EVTPHSFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILT 208 Query: 142 ECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR--IPESILGTITSAVLKGL 199 + IV Y +F S + +CMEY GG L + +PE + V L Sbjct: 209 KSKHPFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAAL 268 Query: 200 SYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVS 234 YL ++RD+KP NIL++ +G I + DF +S Sbjct: 269 EYLH-LMGFIYRDLKPENILLHQSGHIMLSDFDLS 302 >SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Schizosaccharomyces pombe|chr 3|||Manual Length = 830 Score = 75.4 bits (177), Expect = 1e-14 Identities = 61/236 (25%), Positives = 108/236 (45%), Gaps = 42/236 (17%) Query: 95 ELGQGNGGVVMKVRHKSTGLIMARK-LIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYG 153 E+G+G+ +V K +H T +++ K ++ ++ + + + E+ +L E H+V Sbjct: 19 EIGRGSFAIVYKGKHTETNRVISIKSVLTKKLTKKLLENLESEISILKEIRHVHVVELID 78 Query: 154 AFYSDGEISICMEYMDGGSLDLILKKAGR---IP------------------ESILGTIT 192 + I + MEY G L ++K + IP E+++ T Sbjct: 79 CIKAGRFIHLVMEYCSLGDLSYFIRKREKFNSIPSLAWINIDHPPVYKAGLNETLVRHFT 138 Query: 193 SAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGE------------------IKICDFGVS 234 + L +LR + +++HRDVKP N+L+ +K+ DFG + Sbjct: 139 QQLASALQFLRSR-SLIHRDVKPQNLLLQPPPTAAYLEEHPQFVGSPKLPMLKLADFGFA 197 Query: 235 GQL-IDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPD 289 L SMA + G+ YM+PE L+ Y ++D+WS+G L EMA+G P P+ Sbjct: 198 RYLQTSSMAETLCGSPLYMAPEILRYEKYDAKADLWSVGAVLYEMAVGKPPFKAPN 253 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 75.4 bits (177), Expect = 1e-14 Identities = 57/198 (28%), Positives = 104/198 (52%), Gaps = 20/198 (10%) Query: 111 STGLIMARKLIHLEVKPAIKKQII------RELKVLHECNFAHIVGFYGAFYSDGE---- 160 S G++M LI + K AIK+ + REL+++ +IV +Y+ G+ Sbjct: 42 SFGVVMQVHLIESDSKAAIKRVLQDKRFKNRELQIMRIMKHPNIVDLIAYYYTTGDNSDE 101 Query: 161 --ISICMEYMDGG---SLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKP 215 +++ +E+M + L ++ +P + +L+ L+Y+ I HRD+KP Sbjct: 102 VYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHAS-GICHRDIKP 160 Query: 216 SNILVN-SNGEIKICDFGVSGQLIDSMAN-SFVGTRSYMSPERLQG-THYSVQSDIWSLG 272 N+L++ NG +K+CDFG + L+ N S++ +R Y +PE + G T Y+ DIWS G Sbjct: 161 QNLLLDPENGILKLCDFGSAKILVAGEPNVSYICSRYYRAPELIFGATDYTHAIDIWSTG 220 Query: 273 LSLVEMAIGMYPIPPPDA 290 + E+ +G +P+ P ++ Sbjct: 221 CVMAELMLG-HPLFPGES 237 >SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomyces pombe|chr 1|||Manual Length = 607 Score = 74.5 bits (175), Expect = 2e-14 Identities = 45/156 (28%), Positives = 77/156 (49%), Gaps = 3/156 (1%) Query: 85 LSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIK--KQIIRELKVLHE 142 +S DF+ + ++GQG G V R + T I+A K+++ V + + ++ E +L Sbjct: 203 ISHGDFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDEIRHVLTERDILTT 262 Query: 143 CNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202 N +V AF I + ME++ GG +L +G + + + + + L Sbjct: 263 ANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFYATEMFLAIDAL 322 Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLI 238 I HRD+KP N LV ++G IK+ DFG+S +I Sbjct: 323 HQLGYI-HRDLKPENFLVGASGHIKLTDFGLSSGII 357 Score = 46.0 bits (104), Expect = 1e-05 Identities = 41/139 (29%), Positives = 60/139 (43%), Gaps = 19/139 (13%) Query: 242 ANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQN 301 A+S VG+ YM+PE L+G +Y+ D WSLG + E G PP F G N Sbjct: 400 AHSVVGSPDYMAPEVLRGENYNHSVDYWSLGCIMYECLSG---FPP---------FSGSN 447 Query: 302 EDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLK 361 + + N + F+ Y + P L + D+ DFV C+ D LK Sbjct: 448 VNETWSNLKNWRK---CFQRPHY---DDPRDLEFN-WRDDAWDFVCHCITDPKDRFCSLK 500 Query: 362 TLMNHEWIRKAEAEKVDIA 380 +M H + K + + V A Sbjct: 501 QVMQHPYFSKIDWKNVRTA 519 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 74.1 bits (174), Expect = 3e-14 Identities = 45/150 (30%), Positives = 76/150 (50%), Gaps = 4/150 (2%) Query: 132 QIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTI 191 Q + L+ L C F +V + + I + ++Y + G L L L + G + + Sbjct: 337 QEVSILQRLQACPF--VVNLVNVWSYNDNIFLQLDYCENGDLSLFLSELGLLQVMDPFRV 394 Query: 192 TSAVLKGLSYLRDKHAI--MHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTR 249 + + L H + +H DVKPSN+L+ +G +K+ DFG++ L S G R Sbjct: 395 WKMLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGNLKLGDFGLATSLPVSSMVDLEGDR 454 Query: 250 SYMSPERLQGTHYSVQSDIWSLGLSLVEMA 279 Y++PE L +Y +D++SLGLS++E A Sbjct: 455 VYIAPEILASHNYGKPADVYSLGLSMIEAA 484 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 74.1 bits (174), Expect = 3e-14 Identities = 71/282 (25%), Positives = 131/282 (46%), Gaps = 46/282 (16%) Query: 109 HKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHEC--NFAHIVGFYGAFYSDGEISICME 166 H+ST ++ K++ + +++RE+ +L N HIV + + I ++ Sbjct: 520 HRSTPQVVI-KIVLSTKQNCQTSRLMREVAILKGLGNNHPHIVKYLDFVKTKHHFGIVLD 578 Query: 167 YMDGGSL-DLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGE 225 Y++GG L D IL + R+ +S+ + + ++ G++YL + ++HRD+K NIL+++N Sbjct: 579 YVNGGELFDYILARR-RLEDSVACRLFAQLISGVAYLHSR-GVVHRDLKLENILLDTNRN 636 Query: 226 IKICDFGVS------GQLID--------SMANSFVGTRSYMSPERLQ---GTHYSVQSDI 268 I I DFG + L + + ++ G+ Y +PE + G + Q+DI Sbjct: 637 IVIADFGFATTFGHFNTLSEHSLPTEKPDLFSTSCGSPCYAAPELVNCKSGMYAGTQADI 696 Query: 269 WSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSPRPMAIFELLDYIVNE 328 WS G+ L M G P ++ H+P N PR L YI + Sbjct: 697 WSCGVILYAMLAGYLPF--------------DDDPHNP-NGENVPR------LYRYICS- 734 Query: 329 PPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIR 370 P + F + +D + + L +P +R + +MNH ++R Sbjct: 735 -TPLIFPEFFKSKARDILKKILVPDPAKRVRMSAIMNHAYLR 775 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 72.9 bits (171), Expect = 7e-14 Identities = 75/313 (23%), Positives = 144/313 (46%), Gaps = 34/313 (10%) Query: 78 QKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH-LEVKPAIKKQIIRE 136 +++ + +++ F KLG +G+G +V ++ + A K ++ + + E Sbjct: 304 RQQDVVTVANLQFIKLGVVGKGGSSMVYRIFSPDNSRLYALKEVNFINADQTTIQGYKNE 363 Query: 137 LKVLHECNFA-HIVGFYGAFYSD--GEISICMEYMDGGSLDLILKKAGR-IPESILGTIT 192 + +L + + I+ Y A +D G++++ ME + +L++K + I + + Sbjct: 364 IALLRKLSGNDRIIKLYAAEVNDTLGQLNMVMECGETDLANLLMKNMKKPINLNFIRMYW 423 Query: 193 SAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMAN----SFVGT 248 +L+ + + D++ I+H D+KP+N L+ G +K+ DFG++ + + N S +GT Sbjct: 424 EQMLEAVQVVHDQN-IVHSDLKPANFLL-VEGNLKLIDFGIAKAIGNDTTNIHRDSHIGT 481 Query: 249 RSYMSPERLQG----THYSVQ-------SDIWSLGLSLVEMAIGMYPIPP-PDAKTLAAI 296 +YM+PE L T+ V+ SD+WSLG L +M G P + +AAI Sbjct: 482 INYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQMVYGRAPFAHLKMIQAIAAI 541 Query: 297 FGGQNEDHSPGQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDE 356 Q H P A L V E LP + D + RCL+++ + Sbjct: 542 PNEQYHIHFPEVA-----------LPANAVQEKEGSLPGVTVGPDLMDVMKRCLERDQRK 590 Query: 357 RADLKTLMNHEWI 369 R + L+ H ++ Sbjct: 591 RLTIPELLVHPFL 603 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 72.5 bits (170), Expect = 1e-13 Identities = 44/144 (30%), Positives = 73/144 (50%), Gaps = 5/144 (3%) Query: 155 FYSDGEISICMEYMDGGS-LDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDV 213 + ++ + E++DGG LD I+ G++ E + LSYL +++++HRD+ Sbjct: 210 YITNSHYYMVFEFVDGGQMLDYIISH-GKLKEKQARKFVRQIGSALSYLH-QNSVVHRDL 267 Query: 214 KPSNILVNSNGEIKICDFGVSG-QLIDSMANSFVGTRSYMSPERLQGTHY-SVQSDIWSL 271 K NIL++ G+IKI DFG+S S +F G+ + +PE L Y + D+WS Sbjct: 268 KIENILISKTGDIKIIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNAQPYIGPEVDVWSF 327 Query: 272 GLSLVEMAIGMYPIPPPDAKTLAA 295 G+ L + G P + L A Sbjct: 328 GIVLYVLVCGKVPFDDQNMSALHA 351 Score = 29.1 bits (62), Expect = 1.2 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 2/48 (4%) Query: 334 PSGIFSDEFKDFVDRCLKKNPDERADLKTLMNHEW-IRKAEAEKVDIA 380 PS + SD K + R L +P +RA L+ ++NH W IR E A Sbjct: 361 PSYLSSD-CKGLLSRMLVTDPLKRATLEEVLNHPWMIRNYEGPPASFA 407 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 72.5 bits (170), Expect = 1e-13 Identities = 48/160 (30%), Positives = 83/160 (51%), Gaps = 9/160 (5%) Query: 131 KQIIRELKVLHECN-FAHIVGFYGAFYSDGEISICMEYMDGGSL-DLILKKAGRIPESIL 188 +++ E+++ CN +I+ FY + + +E+ GG L D I G I E + Sbjct: 56 RRMASEIQLHKLCNGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVG-IDEDVA 114 Query: 189 GTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLI----DSMANS 244 + +++G+S++ K + HRD+KP NIL++ NG +KI DFG + + NS Sbjct: 115 QFYFAQLMEGISFMHSK-GVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNS 173 Query: 245 FVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 VG+ Y +PE Q + + D+WS G+ L + +G P Sbjct: 174 PVGSPPYAAPEITQ-QYDGSKVDVWSCGIILFALLLGNTP 212 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 71.7 bits (168), Expect = 2e-13 Identities = 53/179 (29%), Positives = 82/179 (45%), Gaps = 20/179 (11%) Query: 125 VKPAIKKQIIRELKV----LHECNFAHIVGFYG------AFYSDGEISICMEYMDGGSLD 174 +K KK I++E KV + + + GF G F D ++ +E G L Sbjct: 82 IKVLDKKYIVKENKVKYVNIERDSMMRLNGFPGISRLFHTFQDDLKLYYVLELAPNGELL 141 Query: 175 LILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVS 234 +KK + E+ + + +L + Y+ I+HRD+KP NIL + N +KI DFG + Sbjct: 142 QYIKKYRFLDENCVRFYAAEILSSIEYMHSC-GIIHRDLKPENILFDGNMHVKITDFGTA 200 Query: 235 GQLIDSMAN---------SFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 L N SFVGT Y++PE L S SD+W+ + +M +G P Sbjct: 201 KILPPKYVNSPDYTTFPSSFVGTAEYVAPELLSRQVVSKSSDLWAFACVVYQMIVGSPP 259 >SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 71.7 bits (168), Expect = 2e-13 Identities = 59/216 (27%), Positives = 99/216 (45%), Gaps = 22/216 (10%) Query: 92 KLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVG 150 +LG+ LG G+ V +H TG + A K+I P I E+ ++ +I+ Sbjct: 13 RLGKTLGTGSTSCVRLAKHAKTGDLAAIKII-----PIRYASIGMEILMMRLLRHPNILR 67 Query: 151 FYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMH 210 Y + + + +EY+ G L ++K G + E S +L +++ + H Sbjct: 68 LYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCH-RFRFRH 126 Query: 211 RDVKPSNILVNSN-GEIKICDFGVSG-QLIDSMANSFVGTRSYMSPERLQGTHY-SVQSD 267 RD+K NIL+ N +IKI DFG++ + DS ++ G+ Y++PE + Y +D Sbjct: 127 RDLKLENILIKVNEQQIKIADFGMATVEPNDSCLENYCGSLHYLAPEIVSHKPYRGAPAD 186 Query: 268 IWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNED 303 +WS G+ L + P FGGQN D Sbjct: 187 VWSCGVILYSLLSNKLP------------FGGQNTD 210 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 70.9 bits (166), Expect = 3e-13 Identities = 62/207 (29%), Positives = 101/207 (48%), Gaps = 21/207 (10%) Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR--ELKVLHECNFAHIVGFYG 153 LG G + +TG A K+I + K K+ E+ +L + + +I+ Sbjct: 166 LGIGGFSRIYMAMDNNTGGQYACKII--DKKKISTKRFFEDHEMTILRKLDHPNIIKVNM 223 Query: 154 AFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDV 213 + S+ + I E + GG L L K G +PE I +L+GL YL +++ I+HRD+ Sbjct: 224 EYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQGLKYLHEQN-IIHRDL 282 Query: 214 KPSNILVNSNGE----IKICDFGVSGQL-IDSMANSFVGTRSYMSPE--RLQG------- 259 K NIL+ S+ + I + DFGV+ + ++FVGT Y +PE RL+G Sbjct: 283 KLENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFVGTPEYTAPEIQRLKGRSQVEKE 342 Query: 260 --THYSVQSDIWSLGLSLVEMAIGMYP 284 + Y + D+WSLG+ + + G P Sbjct: 343 NSSGYGKEVDLWSLGVIMFLLLSGNSP 369 Score = 30.3 bits (65), Expect = 0.51 Identities = 11/33 (33%), Positives = 18/33 (54%) Query: 339 SDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371 S + KD + LK NP +R +K ++H W + Sbjct: 391 SRQAKDLISNLLKTNPPDRFTVKQCLSHPWFAR 423 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 70.5 bits (165), Expect = 4e-13 Identities = 64/219 (29%), Positives = 100/219 (45%), Gaps = 28/219 (12%) Query: 89 DFEKLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE--CNF 145 DF K GE LG+G+ V+ ST A K+ L+ + IK++ + + + E C Sbjct: 98 DF-KFGEILGEGSYSTVLTATENSTKREYAIKV--LDKRHIIKEKKEKYVNIEKEALCIL 154 Query: 146 AHIVGFYGAFYSDGE---ISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202 + GF FY+ + + + G L + K GR E + ++ + Y+ Sbjct: 155 SKHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYM 214 Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSM-----------------ANSF 245 + ++HRD+KP NIL++ N KI DFG S ++++S + SF Sbjct: 215 HGR-GVIHRDLKPENILLDDNMRTKITDFG-SAKILNSSHGSHEEDTHHADKPQAHSRSF 272 Query: 246 VGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 VGT Y+SPE L SDIW+ G L +M G P Sbjct: 273 VGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPP 311 >SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosaccharomyces pombe|chr 3|||Manual Length = 477 Score = 69.7 bits (163), Expect = 7e-13 Identities = 58/199 (29%), Positives = 89/199 (44%), Gaps = 10/199 (5%) Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIH---LEVKPAIKK-QIIRELKVLHECNFAHIVGF 151 LG+G V+ ++ A K+I + K +K+ I+ L+ HI+ + Sbjct: 165 LGKGMFSTVVSALDRNRNQTFAIKIIRNNEVMYKEGLKEVSILERLQAADREGKQHIIHY 224 Query: 152 YGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSA--VLKGLSYLRDKHAI 208 F + + E + D ILKK GR + SI A + L L+ + I Sbjct: 225 ERHFMHKNHLCMVFEMLSLNLRD-ILKKFGRNVGLSIKAVRLYAYQMFMALDLLKQCNVI 283 Query: 209 MHRDVKPSNILVNSNGEI-KICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSD 267 H D+KP N+LVN I KICD G + ++ ++ +R Y +PE + G YS D Sbjct: 284 -HSDIKPDNMLVNEKRNILKICDLGSASDASENEITPYLVSRFYRAPEIILGFPYSCPID 342 Query: 268 IWSLGLSLVEMAIGMYPIP 286 WS+G SL E+ G P Sbjct: 343 TWSVGCSLYELYTGQILFP 361 Score = 27.9 bits (59), Expect = 2.7 Identities = 10/35 (28%), Positives = 19/35 (54%) Query: 337 IFSDEFKDFVDRCLKKNPDERADLKTLMNHEWIRK 371 I E D +++CL+ NP++R + + H + K Sbjct: 442 IIRQELMDLLEKCLELNPEKRVPPEVALKHPFFIK 476 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 68.9 bits (161), Expect = 1e-12 Identities = 54/198 (27%), Positives = 88/198 (44%), Gaps = 9/198 (4%) Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155 +G+G+ G V H T + K + + ++I ++LH +I Y Sbjct: 37 VGEGSFGKVYLAAHLLTNTKVVLKSSCRKQAIILAREIHHHRRLLHP----NITRLYEVV 92 Query: 156 YSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKP 215 ++ I + MEY G L + + R+ E I + + YL + +HRD+K Sbjct: 93 CTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQLCCAIQYLH-RQGCVHRDLKL 151 Query: 216 SNILVNSNGEIKICDFGVSGQLIDS---MANSFVGTRSYMSPERLQGTHYSVQS-DIWSL 271 NI ++ +K+ DFG S S N+ GT +Y +PE +QG Y + DIWSL Sbjct: 152 ENIFLDKAYNVKLGDFGFSRDSDCSRRTFMNTRCGTVAYCAPELVQGHKYIGECVDIWSL 211 Query: 272 GLSLVEMAIGMYPIPPPD 289 G+ + + IG P D Sbjct: 212 GIIMYALLIGRLPFDEDD 229 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 68.9 bits (161), Expect = 1e-12 Identities = 53/196 (27%), Positives = 93/196 (47%), Gaps = 7/196 (3%) Query: 90 FEKLGELGQGNGGVVMKVRH--KSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECN-FA 146 F + LG G V +V + T +KL P + ++++E+ + Sbjct: 566 FRNVTLLGSGEFSEVFQVEDPVEKTLKYAVKKLKVKFSGPKERNRLLQEVSIQRALKGHD 625 Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAG---RIPESILGTITSAVLKGLSYLR 203 HIV ++ G + + +E + GSLD L++ G R+ E + I V GL ++ Sbjct: 626 HIVELMDSWEHGGFLYMQVELCENGSLDRFLEEQGQLSRLDEFRVWKILVEVALGLQFIH 685 Query: 204 DKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYS 263 K+ + H D+KP+N+++ G +KI DFG++ G Y++PE L Y Sbjct: 686 HKNYV-HLDLKPANVMITFEGTLKIGDFGMASVWPVPRGMEREGDCEYIAPEVLANHLYD 744 Query: 264 VQSDIWSLGLSLVEMA 279 +DI+SLG+++ E A Sbjct: 745 KPADIFSLGITVFEAA 760 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 68.5 bits (160), Expect = 2e-12 Identities = 63/219 (28%), Positives = 104/219 (47%), Gaps = 25/219 (11%) Query: 90 FEKLGELGQGNGGVVMKVRHKSTGLIMARKLI-HLEVKPAI--------KKQIIRELKVL 140 +E + ELG+G G V R T ++A K+I E +P + K+++ RE+ +L Sbjct: 135 YEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRREIAIL 194 Query: 141 HECNFAHIVGFYGAFY--SDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKG 198 +C ++V S ++ + +EYM GG + + + S V+ G Sbjct: 195 KKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRDVVLG 254 Query: 199 LSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVS-------GQLIDSMANSFVGTRSY 251 L YL + I+HRD+KP+N+L+NS+ +KI DFGVS + D VGT ++ Sbjct: 255 LEYLHYQ-GIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVELAKTVGTPAF 313 Query: 252 MSPERL------QGTHYSVQSDIWSLGLSLVEMAIGMYP 284 +PE S D+W+LG++L + G P Sbjct: 314 FAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCP 352 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 68.5 bits (160), Expect = 2e-12 Identities = 47/153 (30%), Positives = 78/153 (50%), Gaps = 6/153 (3%) Query: 86 SDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR---ELKVLHE 142 S +D++ L + +G G V + ++TG A K++ A K Q+I E +L Sbjct: 585 SINDYKILKPISKGAFGSVYLAQKRTTGDYFAIKILKKSNMIA-KNQVINVRAERAILMS 643 Query: 143 CNFAHIVG-FYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSY 201 + V Y F S + + MEY++GG +LK G + + T + + L Sbjct: 644 QGESPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDWIRTYIAETVLCLGD 703 Query: 202 LRDKHAIMHRDVKPSNILVNSNGEIKICDFGVS 234 L D+ I+HRD+KP N+L++ NG +K+ DFG+S Sbjct: 704 LHDR-GIIHRDIKPENLLISQNGHLKLTDFGLS 735 Score = 35.9 bits (79), Expect = 0.010 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%) Query: 245 FVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIF 297 F+GT Y++PE + G SD WSLG + E G PP +A+T +F Sbjct: 857 FIGTPDYIAPEVILGNPGIKASDWWSLGCVVFEFLFG---YPPFNAETPDQVF 906 >SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Ppk34|Schizosaccharomyces pombe|chr 3|||Manual Length = 354 Score = 68.1 bits (159), Expect = 2e-12 Identities = 49/161 (30%), Positives = 78/161 (48%), Gaps = 11/161 (6%) Query: 133 IIRELKVLHECNFAHIVGFYGAFYSDGEISICM--EYMDGGSLDLILKKAGRIP---ESI 187 I +EL VL + ++V Y SD + S+CM Y GG L + P E+ Sbjct: 118 IRKELDVLKVLDHENVVKLYQVINSDYKDSLCMVLNYCPGGKLASVDHGISFDPMPLETC 177 Query: 188 LGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQL-IDSMANSFV 246 + VL ++Y+ K ++HRD+KP NIL N + + DFG++ L D Sbjct: 178 RKSFRQLVL-AVNYIHGK-GVIHRDIKPDNILFKENNNLCVIDFGLAEFLPKDGFVKPAS 235 Query: 247 GTRSYMSPERLQGTHYSVQS---DIWSLGLSLVEMAIGMYP 284 GT ++M+PE ++ DIWS+G++L +A +P Sbjct: 236 GTPAFMAPELFDNELKKIKGKPLDIWSMGVTLYVIAFAEFP 276 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 67.7 bits (158), Expect = 3e-12 Identities = 38/125 (30%), Positives = 66/125 (52%), Gaps = 4/125 (3%) Query: 163 ICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNS 222 I EY+ GG L + G++ E + + ++ L YL K+ I+HRD+K N+L+ Sbjct: 127 ILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYLH-KNFIVHRDLKIENVLLTQ 185 Query: 223 NG-EIKICDFGVSG-QLIDSMANSFVGTRSYMSPERLQGTHY-SVQSDIWSLGLSLVEMA 279 + ++K+ DFG+S D + ++ G+ + +PE L Y + D+WSLG+ + M Sbjct: 186 DSRQVKLIDFGLSNFYSKDDLLRTYCGSLYFAAPELLDAKPYIGPEVDVWSLGVVIYVMV 245 Query: 280 IGMYP 284 G P Sbjct: 246 CGRVP 250 >SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosaccharomyces pombe|chr 1|||Manual Length = 469 Score = 66.9 bits (156), Expect = 5e-12 Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 3/152 (1%) Query: 85 LSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARK-LIHLEV-KPAIKKQIIRELKVLHE 142 LS +DF + +G+G G V V+ TG I A K L+ E+ K + E +L E Sbjct: 88 LSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLVE 147 Query: 143 CNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYL 202 + +V Y AF + + ME++ GG L +L E + + + ++ + Sbjct: 148 SDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADV 207 Query: 203 RDKHAIMHRDVKPSNILVNSNGEIKICDFGVS 234 + +HRD+KP NIL++ +G IK+ DFG+S Sbjct: 208 H-RMGYIHRDIKPDNILIDRDGHIKLSDFGLS 238 Score = 35.9 bits (79), Expect = 0.010 Identities = 19/44 (43%), Positives = 22/44 (50%) Query: 241 MANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 MA S VGT Y++PE Y D WSLG + E IG P Sbjct: 288 MAYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWPP 331 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 64.9 bits (151), Expect = 2e-11 Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 10/135 (7%) Query: 158 DGEISIC--MEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKP 215 DG+ C ME GG L ++ AGR+ +++G+ YL D + HRD+KP Sbjct: 426 DGKGDYCEVMELCSGGDLYTLIMAAGRLEPMEADCFFKQLMRGVDYLHDM-GVAHRDLKP 484 Query: 216 SNILVNSNGEIKICDFG------VSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQS-DI 268 N+L+ +G +KI DFG ++ + M G+ Y++PE + + ++ D+ Sbjct: 485 ENLLLTVSGSLKITDFGNGECFRMAWEKEAHMTCGLCGSAPYIAPEEYTESEFDPRAVDV 544 Query: 269 WSLGLSLVEMAIGMY 283 W+ G+ + M G + Sbjct: 545 WACGVIYMAMRTGRH 559 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 63.7 bits (148), Expect = 4e-11 Identities = 56/212 (26%), Positives = 102/212 (48%), Gaps = 13/212 (6%) Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGL-IMARKLIHLEVKPAIKKQIIREL-KVLHECN 144 D+ + + ++G G G V K+ ++A K + ++ +RE+ +L Sbjct: 33 DEVYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSE 92 Query: 145 FAHIVGFYGAFYSDGE-ISICMEYMDGGSLDLI-LKKAGRIPESILGTITSAVLKGLSYL 202 +IV + + + I ME++D LI +K + + I + KGL+++ Sbjct: 93 NENIVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHI 152 Query: 203 RDKHAIMHRDVKPSNILVNSNGE-----IKICDFGVSGQLIDSMA-NSFVGTRSYMSPE- 255 + HRD+KP NIL++SN + +KI DFG++ ++ +V TR Y +PE Sbjct: 153 HT-NGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPEL 211 Query: 256 RLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPP 287 L+ ++YS DI++ G E+A + PI P Sbjct: 212 LLRDSYYSFPVDIYAAGCMAFEIAT-LQPIFP 242 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 62.5 bits (145), Expect = 1e-10 Identities = 57/202 (28%), Positives = 96/202 (47%), Gaps = 19/202 (9%) Query: 95 ELGQGNGGVV-MKVRHKSTGLI--MARKLIHLEVKPAIKKQII--RELKVLHECN-FAHI 148 +LG G+ G V + R + GL +A K + KP K +++ RE L + + + Sbjct: 26 KLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRKISKHPCL 85 Query: 149 VGFYGAFYSD-GEISICMEYMDGGSLDLILKKAGRI-PESILGTITSAVLKGLSYLRDKH 206 + F I + ME+MD L ++ GR+ + I ++ G+ ++ KH Sbjct: 86 IDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGIEHIH-KH 144 Query: 207 AIMHRDVKPSNILV--------NSNGEIKICDFGVSGQLIDS-MANSFVGTRSYMSPE-R 256 MHRD+KP NILV +S IK+ DFG++ + S +V TR Y +PE Sbjct: 145 GFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLTEYVSTRWYRAPELL 204 Query: 257 LQGTHYSVQSDIWSLGLSLVEM 278 L+ Y+ D+++ G + E+ Sbjct: 205 LRSGSYNHSVDLYAFGCIVFEI 226 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 62.1 bits (144), Expect = 1e-10 Identities = 55/182 (30%), Positives = 90/182 (49%), Gaps = 20/182 (10%) Query: 126 KPAIK-KQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSL-DLILKK---- 179 KPA Q + L+ L +I+ F +F + + +EY G L + IL Sbjct: 47 KPAYTFLQEVNILRQLSRSRHRNIIHFVESFEDNVYYYVVLEYCPLGDLYECILNNDFPN 106 Query: 180 AGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGE-----IKICDFGVS 234 A PE I I ++ G+++L H I HRD+KP N L++ + + +KI DFG++ Sbjct: 107 AKNQPEMIKN-IFLQIIDGVAHLHS-HGIYHRDLKPENFLLSLSEDGSELVVKISDFGLA 164 Query: 235 GQLIDSMANSF-VGTRSYMSPERLQ---GTHYSVQ-SDIWSLGLSLVEMAIGMYPIPPPD 289 + D ++ F G+ YM+PE+ + G YS + +DIW+LG+ L+ + P P Sbjct: 165 CR--DKISYDFGTGSDRYMAPEQFEEVDGAGYSPRAADIWALGICLLNLIFARNPFTYPH 222 Query: 290 AK 291 K Sbjct: 223 EK 224 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 61.7 bits (143), Expect = 2e-10 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 11/139 (7%) Query: 156 YSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKP 215 YSD ++ G L LI + R+ + + +L+GL+Y+ + I HRD+KP Sbjct: 529 YSDTWCAVMDFCPRGDLLSLIEDRHDRLGKKDFECMIKQILRGLNYIHSQ-GIAHRDIKP 587 Query: 216 SNILVNSNGEIKICDFGVSGQL---------IDSMANSFVGTRSYMSPERL-QGTHYSVQ 265 NIL++ G ++I DFG L ++S + G+ YM+PE L G++ + Sbjct: 588 ENILISEYGVLRITDFGACDVLCNPGDDITAVESKSMGIFGSDPYMAPEILTPGSYNAFF 647 Query: 266 SDIWSLGLSLVEMAIGMYP 284 +D+WS + L + YP Sbjct: 648 ADMWSTAIVLHCLYFRTYP 666 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 60.9 bits (141), Expect = 3e-10 Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 21/136 (15%) Query: 163 ICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNS 222 I MEY + SL I++ +IP + + +L+ L+Y+ + +MHRD+KP NI ++ Sbjct: 726 IQMEYCEKLSLQDIIRD--KIPVDEMWRLFRQILEALAYIHSR-GMMHRDLKPGNIFLDE 782 Query: 223 NGEIKICDFGV---------------SGQLIDSMANSFVGTRSYMSPE---RLQGTHYSV 264 N +K+ DFG+ + Q D + VGT Y++PE R G Y Sbjct: 783 NRNVKLGDFGLATENENYQDNNDKWKNRQSADEDLTTGVGTALYVAPELLSRRNGVRYDA 842 Query: 265 QSDIWSLGLSLVEMAI 280 + D++SLG+ L EM + Sbjct: 843 KVDMYSLGIILFEMCM 858 Score = 42.3 bits (95), Expect = 1e-04 Identities = 23/69 (33%), Positives = 38/69 (55%) Query: 87 DDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFA 146 + DFE+L LG+G G V+KV+++ G A K + L +I+RE+ L + Sbjct: 553 ETDFEELEFLGRGGFGEVVKVKNRIDGRFYAVKKLVLLSDDKENSRILREVMTLSRLHHE 612 Query: 147 HIVGFYGAF 155 H+V +Y A+ Sbjct: 613 HVVRYYTAW 621 Score = 30.7 bits (66), Expect = 0.38 Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 174 DLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGV 233 D++L+ A + E I+ S + + +R K+ M VK NIL N + EI+ + G+ Sbjct: 1361 DIVLRGASSL-EEIVTHYRSEGINWVLVVRQKNTQMEHSVKARNILKNEDDEIRFDEVGM 1419 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 58.8 bits (136), Expect = 1e-09 Identities = 47/187 (25%), Positives = 85/187 (45%), Gaps = 14/187 (7%) Query: 195 VLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVS---GQLIDSMANSF----VG 247 +L+ ++YL+ + I HRD+KP NIL+ +G +K+ DFG S G D+ + F VG Sbjct: 240 ILQAVAYLQSQR-IAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRFVSGAVG 298 Query: 248 TRSYMSPERLQGTHY-SVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSP 306 + +Y++PE Y + +D WS G+ L + G +P KT ++ + Sbjct: 299 SLAYLAPEAFHENEYCGLLADRWSCGILLKVLFTGYFPF-KTSVKT--DLYYSKYMSILT 355 Query: 307 GQAPNSPRPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTLMNH 366 S + F+ ++ + P P + K + L + R L +++ Sbjct: 356 DTCGISSTDESSFQ--TEVIKQIPTLQPLRYIPEGAKKIILSLLNPDSQNRPSLDSILGT 413 Query: 367 EWIRKAE 373 W+RK + Sbjct: 414 AWVRKLD 420 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 57.2 bits (132), Expect = 4e-09 Identities = 53/209 (25%), Positives = 91/209 (43%), Gaps = 19/209 (9%) Query: 90 FEKLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHL----EVKPAIKKQIIRELKVLHECN 144 + K G LG G GG V ++ S G I A K E + +++ E + + Sbjct: 301 YGKFGRMLGSGAGGSVRIMKRSSDGKIFAVKEFRARRPTETEREYARKVTAEFCIGSALH 360 Query: 145 FAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRD 204 +I+ + + MEY +++ +PE + +L G++YL Sbjct: 361 HTNIIETLDIVEENKKFYEVMEYAPYDMFSIVMSGKMTMPE--VYCCFKQLLSGVAYLHS 418 Query: 205 KHAIMHRDVKPSNILVNSNGEIKICDFG--------VSGQLIDSMANSFVGTRSYMSPER 256 + HRD+K N++V+SN +KI DFG +++ A VG+ Y++PE Sbjct: 419 M-GLAHRDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIVE--ATGVVGSDPYLAPET 475 Query: 257 LQGTHYSVQS-DIWSLGLSLVEMAIGMYP 284 L Y ++ DIWS + MA+ +P Sbjct: 476 LVRKLYDPRAVDIWSSAIIFCCMALRRFP 504 >SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase Ppk6|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 56.8 bits (131), Expect = 5e-09 Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 1/69 (1%) Query: 208 IMHRDVKPSNILVNSNGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY-SVQS 266 I+HRD+K N+++ NG ++ DFG S + ++F GT + +PE L+G Y + Sbjct: 632 IIHRDIKDENVILEGNGCARLIDFGSSSLTKNGPFDTFRGTVGFAAPELLRGEKYLGKEQ 691 Query: 267 DIWSLGLSL 275 DIW+LG+ L Sbjct: 692 DIWALGILL 700 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 56.0 bits (129), Expect = 9e-09 Identities = 59/212 (27%), Positives = 93/212 (43%), Gaps = 30/212 (14%) Query: 96 LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAF 155 LG G G V++ +STG A K+ P ++ + EL+VL + Sbjct: 368 LGHGTFGKVIQCYDQSTGRHCAIKVTR--AIPKYREASLIELRVLQTIAHSDPTNENKCI 425 Query: 156 ----YSDGEISICMEY-MDGGSLDLILKKAGRIPESI--LGTITSAVLKGLSYLRDKHAI 208 Y D IC+ + G S+ LK IP + + ++ + K +++L + Sbjct: 426 QLRDYFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQMLSQQLFKSVAFLHSL-GL 484 Query: 209 MHRDVKPSNILVNSNG-------------------EIKICDFGVSGQLIDSMANSFVGTR 249 +H D+KP N+L+ SN EI++ DFG S D +S V TR Sbjct: 485 VHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFG-SATFEDEYHSSVVSTR 543 Query: 250 SYMSPERLQGTHYSVQSDIWSLGLSLVEMAIG 281 Y +PE + G +S D+WS+G LVE+ G Sbjct: 544 HYRAPEIILGLGWSYPCDVWSIGCILVELFTG 575 Score = 26.2 bits (55), Expect = 8.2 Identities = 9/26 (34%), Positives = 15/26 (57%) Query: 305 SPGQAPNSPRPMAIFELLDYIVNEPP 330 SP PN P P ++ +L ++ +PP Sbjct: 34 SPRLTPNLPPPFSVHQLQSFVPPQPP 59 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 52.8 bits (121), Expect = 8e-08 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 10/96 (10%) Query: 191 ITSAVLKGLSYLRDKHAIMHRDVKPSNILVNS-NGEIKICDFGVS------GQLIDSMAN 243 I + L YL +KH I+HRD+ P+NIL++S NG + DF ++ G+ + + Sbjct: 109 IVLQISSALEYL-EKHGILHRDIHPNNILLDSMNGPAYLSDFSIAWSKQHPGEEVQELIP 167 Query: 244 SFVGTRSYMSPERLQGTH-YSVQSDIWSLGLSLVEM 278 +GT Y + E L G H Y + D W+ G+ + E+ Sbjct: 168 Q-IGTGHYRAIETLFGCHSYGHEVDRWTFGILIAEL 202 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 52.0 bits (119), Expect = 1e-07 Identities = 70/290 (24%), Positives = 119/290 (41%), Gaps = 16/290 (5%) Query: 82 IGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLE-VKPAIKKQIIRELKVL 140 +G++ D + +G G GVV K G + A K + + + KK REL L Sbjct: 10 LGQVLGDSLRFVSIIGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQAREL-AL 68 Query: 141 HECNFAH--IVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKG 198 H +H I+ + ++ I + ++Y G L + + ++ + I + L+ Sbjct: 69 HARVSSHPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEK-KVYQGNSHLIKTVFLQL 127 Query: 199 LSYLRDKHA--IMHRDVKPSNILV-NSNGEIKICDFGVSGQLIDSMANSF-VGTRSYMSP 254 +S + H+ I HRD+KP NI+V N + + DFG++ + ++ F G+ YMSP Sbjct: 128 ISAVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGLA--TTEPYSSDFGCGSLFYMSP 185 Query: 255 E-RLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHSPGQAPNSP 313 E + + S SD+ + +E + P D L I +P + S Sbjct: 186 ECQREVKKLSSLSDMLPVTPEPIESQSSSFATAPNDVWALGIILINLCCKRNPWKRACSQ 245 Query: 314 RPMAIFELLDYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDERADLKTL 363 Y+ N P L S E ++R +NP R L L Sbjct: 246 TDGT---YRSYVHN-PSTLLSILPISRELNSLLNRIFDRNPKTRITLPEL 291 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 51.6 bits (118), Expect = 2e-07 Identities = 57/261 (21%), Positives = 108/261 (41%), Gaps = 22/261 (8%) Query: 85 LSDDDFEKLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIR----ELKV 139 ++D + KL +G+G + + ++ I K+ + ++ ++ +R E Sbjct: 235 VTDTPYGKLNNVIGEGASSFIRVINDRNKLPIYVAKVFRPPLDTSLLRRYVRYFIAEYTF 294 Query: 140 LHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGL 199 +I+ Y I +EY+ I K G + +L G+ Sbjct: 295 ASTLRHPNIIKVLDIIYKRHTILQIIEYVPYDLFTFITK--GHCSALKADQMFFQLLDGV 352 Query: 200 SYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVS------GQLIDSMANSFVGTRSYMS 253 +Y+ I HRD+K NI+++ N +KI DFG + + M++ VG++ Y++ Sbjct: 353 AYMHSL-GIAHRDIKLDNIMLDENLNVKIIDFGTAFVFHYPFESTTLMSDGVVGSKPYVA 411 Query: 254 PERLQGTHYSVQS-DIWSLGLSLVEMAIGMYP--IPPPDAKTLAAIFGGQNEDHSPGQAP 310 PE L Y + D+WS + +A+ +P +P K +N+ ++ Q Sbjct: 412 PEVLTQKPYDPSAVDVWSCAIVYCCIALKRFPWKVPHTSDKRFNLYVTQRNDPNTKSQLI 471 Query: 311 NSPRPM----AIFELLDYIVN 327 S PM I+ +LD N Sbjct: 472 ES-LPMNSRDTIYHMLDIDFN 491 >SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizosaccharomyces pombe|chr 2|||Manual Length = 413 Score = 50.0 bits (114), Expect = 6e-07 Identities = 55/184 (29%), Positives = 80/184 (43%), Gaps = 29/184 (15%) Query: 124 EVKPAIK--KQIIRELKVL-HECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKA 180 E K +K +Q I LK L H C +V + S E+ + Y GG L KK Sbjct: 144 EKKARVKVFRQEIWALKTLSHPC----VVQLLNYYVSSAELILVENYCMGGDLYHYTKKH 199 Query: 181 -GRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNS---------------NG 224 +G I S ++ ++YL K ++HRD+K NIL+ N Sbjct: 200 HSDFSLEFVGRIFSELVHTVAYLHSK-CLIHRDLKLENILLTQPYNVIKTIDNWKNYPNA 258 Query: 225 EIKICDFGVSGQLIDS---MANSFVGTRSYMSPERLQG-THYSVQSDIWSLGLSLVEMAI 280 I+I DF +S +DS + S G++ Y PE G H ++D WSLG+ L + Sbjct: 259 LIQISDFELS-IFVDSKNHLVQSSCGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFALLE 317 Query: 281 GMYP 284 G P Sbjct: 318 GRLP 321 >SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizosaccharomyces pombe|chr 2|||Manual Length = 872 Score = 48.8 bits (111), Expect = 1e-06 Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 20/137 (14%) Query: 160 EISICMEYMDGGSL-DLILKKAG-RIPESILGTITSAVLKGLSYLRD-KHAIMHRDVKPS 216 EI + MEY GG L D + ++ R+ E + I S +++G++ L + ++HRD+K Sbjct: 108 EILLLMEYCAGGGLIDFMNQRLQTRLSEHEVLKIISDIVQGVASLHYLRPPLIHRDLKVE 167 Query: 217 NILVNSNGEIKICDFG------------VSGQLIDSMANSFVGTRSYMSPERL---QGTH 261 N+L++ N K+CDFG Q ++ N+F T Y +PE + G Sbjct: 168 NVLLSFN-TFKLCDFGSVTEPMHAAENSSEIQALEKSINTFT-TYQYRAPEMINLYSGLG 225 Query: 262 YSVQSDIWSLGLSLVEM 278 +SD+W+LG+ L ++ Sbjct: 226 IDEKSDMWALGVLLYKL 242 >SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Schizosaccharomyces pombe|chr 1|||Manual Length = 332 Score = 47.6 bits (108), Expect = 3e-06 Identities = 48/193 (24%), Positives = 88/193 (45%), Gaps = 16/193 (8%) Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHE-CNFA 146 D++E + ++G+G V + ++ K I +KP K+I RE+K+L Sbjct: 41 DNYEIIRKVGRGKYSEVFE----GLNVLNNSKCIIKVLKPVKYKKIKREIKILQNLAGGP 96 Query: 147 HIVGFYGAFYSDGEI---SICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLR 203 +I+ D E S+ E++D + + + + + +LK L + Sbjct: 97 NIISLLD-IVRDPESKTPSLIFEFVDNIDFRTLYPT---LSDYDIRYYSYELLKALDFCH 152 Query: 204 DKHAIMHRDVKPSNILV-NSNGEIKICDFGVSGQLIDSMA-NSFVGTRSYMSPERL-QGT 260 + IMHRDVKP N+++ + ++++ D+G++ M N V +R + PE L Sbjct: 153 SR-GIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYHAGMEYNVRVASRYFKGPELLVDFR 211 Query: 261 HYSVQSDIWSLGL 273 Y DIWS G+ Sbjct: 212 EYDYSLDIWSFGV 224 >SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 580 Score = 45.6 bits (103), Expect = 1e-05 Identities = 22/61 (36%), Positives = 33/61 (54%) Query: 224 GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMY 283 G I++ DFG+S + DS + GT Y +PE ++ YS D+W+LG L + G Sbjct: 302 GRIRLADFGLSKVVWDSHTQTPCGTMGYTAPEIVRDERYSKGVDMWALGCVLYTILCGFP 361 Query: 284 P 284 P Sbjct: 362 P 362 Score = 45.2 bits (102), Expect = 2e-05 Identities = 32/146 (21%), Positives = 66/146 (45%), Gaps = 11/146 (7%) Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLI-----HLEVKPAIKKQ------IIRE 136 + + L ++G G V K H TG +A K++ + + + K+Q I++E Sbjct: 122 EQYTLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKE 181 Query: 137 LKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVL 196 ++++ +I+ + + +E DGG L + + E + + + V Sbjct: 182 VQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVITQVA 241 Query: 197 KGLSYLRDKHAIMHRDVKPSNILVNS 222 + YL + ++HRD+KP N+L +S Sbjct: 242 HAIRYLHEDCGVVHRDIKPENLLFDS 267 Score = 26.6 bits (56), Expect = 6.2 Identities = 10/31 (32%), Positives = 15/31 (48%) Query: 339 SDEFKDFVDRCLKKNPDERADLKTLMNHEWI 369 S KD + L +P+ R D+ + H WI Sbjct: 391 SKSAKDLISHLLTVDPESRYDIHQFLAHPWI 421 >SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schizosaccharomyces pombe|chr 1|||Manual Length = 504 Score = 45.2 bits (102), Expect = 2e-05 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Query: 224 GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMY 283 G I I DFG S + +S + GT Y +PE + YS D+W++G L M G Sbjct: 232 GRILIADFGFSKVVWNSKTATPCGTVGYAAPEIVNDELYSKNVDMWAMGCVLHTMLCGFP 291 Query: 284 PIPPPDAKTLAA-IFGGQNEDHSP 306 P + K LA+ + G+ E SP Sbjct: 292 PFFDENIKDLASKVVNGEFEFLSP 315 Score = 44.4 bits (100), Expect = 3e-05 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 1/133 (0%) Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIH-LEVKPAIKKQIIRELKVLHECNFA 146 + ++ + LG G V K +A K+I E+ ++ + +E+ ++ Sbjct: 63 EKYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQRQGVFKEVNIMRRVKHK 122 Query: 147 HIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH 206 ++V + ++ + ME +GG L + E++ I V + + +L D Sbjct: 123 NVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEAVKHLHDVC 182 Query: 207 AIMHRDVKPSNIL 219 I+HRD+KP N+L Sbjct: 183 GIVHRDIKPENLL 195 >SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 44.8 bits (101), Expect = 2e-05 Identities = 48/185 (25%), Positives = 86/185 (46%), Gaps = 27/185 (14%) Query: 134 IRELKVLHECNFAHIVGFYGAFY-----SDGEISICMEYMD-GGSLDLILKKAG-RIPES 186 +R +K++ N V +YG+ + + E+ + +EY GG +D + + R+ E Sbjct: 82 VRTMKLVS--NQKRCVSYYGSEFFRTSKNQFEVLVLLEYCPCGGLIDFLNTRLQVRLSEQ 139 Query: 187 ILGTITSAVLKGLSYLRD-KHAIMHRDVKPSNILVNSNGEIKICDFG-----VSGQLIDS 240 + I S V + ++ + K ++HRD+K N+L+ + K+CDFG + G + Sbjct: 140 EILKIASDVTEAVAVMHYLKPPLIHRDLKIENVLLAAPNSYKLCDFGSACHPIPGAKTAA 199 Query: 241 MANSF------VGTRSYMSPERL---QGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAK 291 A T Y PE + +G +SDIW+LG+ ++ Y P + + Sbjct: 200 EAKQLEYDIEKFTTWQYRCPEMINVHKGFGIDEKSDIWALGVLFYKLC---YYTTPFEHQ 256 Query: 292 TLAAI 296 LAAI Sbjct: 257 GLAAI 261 >SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces pombe|chr 1|||Manual Length = 704 Score = 40.7 bits (91), Expect = 4e-04 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Query: 89 DFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKP-AIKKQIIRELKVLHECNFAH 147 DFE+L LG+G G V K R+K G+ A K I L ++ + I RE + L N + Sbjct: 223 DFEELELLGKGGYGSVYKARNKFDGVEYALKKIPLRLRSFSTSSNIFRESRTLARLNHPN 282 Query: 148 IVGFYGAF 155 ++ F+ ++ Sbjct: 283 VIRFFSSW 290 Score = 35.1 bits (77), Expect = 0.018 Identities = 14/35 (40%), Positives = 23/35 (65%) Query: 195 VLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKIC 229 +L+G+ YL D ++HRD+KP NI ++S + C Sbjct: 474 ILEGVLYLHDAMHLVHRDLKPRNIFLSSGVHSEPC 508 Score = 27.1 bits (57), Expect = 4.7 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 8/50 (16%) Query: 240 SMANSFVGTRSYMSPERLQGTHYSV-----QSDIWSLGLSLVEMAIGMYP 284 S +SFVGT +Y +PE SV +DI++LG+ E+ +YP Sbjct: 561 SAESSFVGTSTYAAPELFSKHMRSVMNNNSSTDIYALGILFFEL---LYP 607 >SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosaccharomyces pombe|chr 2|||Manual Length = 429 Score = 39.5 bits (88), Expect = 8e-04 Identities = 35/122 (28%), Positives = 62/122 (50%), Gaps = 11/122 (9%) Query: 116 MARKLIHLEVKPAIKKQIIRELKVLHECNFAH-IVGFYGAFYSDGEISICMEYMDGGSL- 173 +A K I+ V P+ +I EL++LHE + ++ A ++ I + ++ Sbjct: 92 VALKRIYATVLPS---RIQTELEMLHELRGSDCVLNMITAVRHQDQVLIVLPFIQHAEFR 148 Query: 174 DLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGEI-KICDFG 232 D +K + +PE +G +LKGL+++ D I+HRD+KP N N + I DFG Sbjct: 149 DFYMKYS--LPE--IGAYLRDLLKGLAHI-DAKGIIHRDIKPGNFAWNPYTQRGVILDFG 203 Query: 233 VS 234 ++ Sbjct: 204 LA 205 >SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schizosaccharomyces pombe|chr 2|||Manual Length = 749 Score = 38.7 bits (86), Expect = 0.001 Identities = 21/89 (23%), Positives = 48/89 (53%), Gaps = 12/89 (13%) Query: 195 VLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSGQLIDS-----------MAN 243 ++ GL +L ++H +++PS+++V++ G+ K+C F S Q ++S + + Sbjct: 157 IIDGLVFLHGSAKVIHYNIRPSSVVVDAKGDWKLCGFSFS-QSVESARYEFNDYDFGIPS 215 Query: 244 SFVGTRSYMSPERLQGTHYSVQSDIWSLG 272 S + +++PE + +SD++S G Sbjct: 216 SLQQSMDFLAPEYITHEIAGPESDVFSFG 244 >SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces pombe|chr 1|||Manual Length = 639 Score = 38.7 bits (86), Expect = 0.001 Identities = 20/68 (29%), Positives = 37/68 (54%) Query: 88 DDFEKLGELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAH 147 +DFE+ LG+G G V VR+K G A K I+ + +I RE+K L + + + Sbjct: 169 EDFEEYSLLGRGGFGSVYHVRNKIDGAEYAMKKINSTFQQMSYSKIFREIKCLAKMDHPN 228 Query: 148 IVGFYGAF 155 ++ ++ ++ Sbjct: 229 VIRYFSSW 236 Score = 30.7 bits (66), Expect = 0.38 Identities = 10/26 (38%), Positives = 19/26 (73%) Query: 195 VLKGLSYLRDKHAIMHRDVKPSNILV 220 ++ G+ Y+ + ++HRD+KPSNI + Sbjct: 400 IINGVMYVHEGVNLIHRDIKPSNIFL 425 >SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosaccharomyces pombe|chr 2|||Manual Length = 365 Score = 37.5 bits (83), Expect = 0.003 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 13/106 (12%) Query: 191 ITSAVLKGLSYLRDKHAIMHRDVKPSNILV---NSNGEIKICDFGVSGQLIDSMAN---- 243 + ++ + ++ K + +HRD+KP N L+ ++ I DFG++ + D + Sbjct: 110 LADQLISRIEFIHSK-SFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIP 168 Query: 244 -----SFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 + GT Y S G S + D+ SLG LV G P Sbjct: 169 YRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLVYFCRGSLP 214 >SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizosaccharomyces pombe|chr 2|||Manual Length = 953 Score = 36.7 bits (81), Expect = 0.006 Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 9/98 (9%) Query: 141 HECNFAHIVGFYGAFYSDGEISICMEYMDGGSL-DLI-LKKAGRIPES----ILGTITSA 194 H N+ Y + E+ + ME+ GG L D + + R+ E IL + A Sbjct: 113 HIVNYIDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNTRLQHRLTEGEILKILADVCDA 172 Query: 195 VLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFG 232 V + YL ++HRD+K N+L+ + K+CDFG Sbjct: 173 VA-AMHYLDPP--LIHRDLKIENVLLVAPNSYKLCDFG 207 Score = 27.1 bits (57), Expect = 4.7 Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 6/72 (8%) Query: 338 FSDEFKDFVDRCLKKNPDERADL-KTLMNHEWIRKAEAEKVDIAGWVCKTMDLMP----- 391 +SD K F+ CL++ P R ++ +TL ++ + D+ G V + P Sbjct: 295 YSDRMKRFIATCLQEQPSHRPNIYQTLKEIMEMQGTPLKLPDVYGGVNASTYNPPRAPLQ 354 Query: 392 STPNSNVSPFSS 403 TP+ +++P SS Sbjct: 355 RTPSGSLTPLSS 366 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 36.7 bits (81), Expect = 0.006 Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 11/104 (10%) Query: 191 ITSAVLKGLSYLRDKHAIMHRDVKPSNILVNSNGE-IKICDFGVSGQLIDSMAN------ 243 + ++ + Y+ K + +HRD+KP N L+ + + + DFG++ + D + Sbjct: 111 LADQLISRIEYVHSK-SFLHRDIKPDNFLMKKHSNVVTMIDFGLAKKYRDFKTHVHIPYR 169 Query: 244 ---SFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 + GT Y S G S + D+ SLG L+ G P Sbjct: 170 DNKNLTGTARYASINTHIGIEQSRRDDLESLGYVLLYFCRGSLP 213 >SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 544 Score = 36.7 bits (81), Expect = 0.006 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 1/62 (1%) Query: 226 IKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPI 285 +KI D G + N V TR Y SPE + G + +D WS + E+ G Y Sbjct: 356 VKIADLGNACWTRKHFTND-VQTRQYRSPEVILGCRWGASADCWSFACIIFELLTGDYLF 414 Query: 286 PP 287 P Sbjct: 415 DP 416 Score = 35.9 bits (79), Expect = 0.010 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 5/79 (6%) Query: 147 HIVGFYGAFYSDGE--ISICM--EYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSY 201 HI+ F G +CM E + L LI R +P I+ I +L L Y Sbjct: 144 HIISLLDYFVHRGPNGAHVCMVFEVLGENLLSLIQSYGHRGVPVGIVKQIAYQLLIALDY 203 Query: 202 LRDKHAIMHRDVKPSNILV 220 L + I+H D+KP N+L+ Sbjct: 204 LHRECGIIHTDLKPENVLI 222 >SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizosaccharomyces pombe|chr 2|||Manual Length = 446 Score = 36.3 bits (80), Expect = 0.008 Identities = 51/210 (24%), Positives = 90/210 (42%), Gaps = 22/210 (10%) Query: 92 KLGE-LGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVG 150 K+G +G+G+ GV+ + + +A K + R K+L C V Sbjct: 13 KVGRRIGEGSFGVIFEGTNLLNNQQVAIKFEPRRSDAPQLRDEYRTYKLLAGCTGIPNVY 72 Query: 151 FYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKH--AI 208 ++G +G +I + + G SL+ +L GR + + T+ A + L+ ++ H ++ Sbjct: 73 YFG---QEGLHNILVIDLLGPSLEDLLDLCGR--KFSVKTVAMAAKQMLARVQSIHEKSL 127 Query: 209 MHRDVKPSNILV---NSNGE--IKICDFGVSGQLIDSMANSFV---------GTRSYMSP 254 ++RD+KP N L+ NS I + DFG+ D + + GT YMS Sbjct: 128 VYRDIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRDPVTKQHIPYREKKNLSGTARYMSI 187 Query: 255 ERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 G S + D+ +LG + G P Sbjct: 188 NTHLGREQSRRDDLEALGHVFMYFLRGSLP 217 >SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1072 Score = 36.3 bits (80), Expect = 0.008 Identities = 45/145 (31%), Positives = 72/145 (49%), Gaps = 20/145 (13%) Query: 135 RELKVLHEC-NFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR--IPESI-LGT 190 RE+ +L + N +IV +Y SD + I +E DLI K + +SI L + Sbjct: 694 REITLLQQSDNHPNIVRYYCKQKSDQFLYIVIELCKCNLSDLIEKPIAYDDLFKSIDLVS 753 Query: 191 ITSAVLKGLSYLRDKHAIMHRDVKPSNIL--VNSNGEIK-------ICDFGVSGQL---I 238 + + G+S+L ++HRD+KP NIL VN++ + I DFG+S +L Sbjct: 754 LLYQIAFGVSHLHSLD-LVHRDLKPQNILLVVNNSPNLSKTRVRALISDFGLSKKLDFNQ 812 Query: 239 DSMANS---FVGTRSYMSPERLQGT 260 S+ N+ G+ + SPE L G+ Sbjct: 813 SSLRNTTFEAAGSYGWRSPEILSGS 837 >SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosaccharomyces pombe|chr 1|||Manual Length = 439 Score = 35.9 bits (79), Expect = 0.010 Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 19/151 (12%) Query: 149 VGFYGAFYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKHA 207 V +YG +G ++ + + G SL+ + GR + I ++ + + ++H Sbjct: 74 VYYYG---QEGMYNLLVMDLLGPSLEDLFDYCGRRFSPKTVAMIAKQMITRIQSVHERHF 130 Query: 208 IMHRDVKPSNILVNSNGE-----IKICDFGVSGQLIDSMAN---------SFVGTRSYMS 253 I +RD+KP N L+ G I DFG++ Q D + S GT YMS Sbjct: 131 I-YRDIKPDNFLIGFPGSKTENVIYAVDFGMAKQYRDPKTHVHRPYNEHKSLSGTARYMS 189 Query: 254 PERLQGTHYSVQSDIWSLGLSLVEMAIGMYP 284 G S + D+ S+G + G P Sbjct: 190 INTHLGREQSRRDDLESMGHVFMYFLRGSLP 220 >SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizosaccharomyces pombe|chr 2|||Manual Length = 435 Score = 33.1 bits (72), Expect = 0.072 Identities = 49/206 (23%), Positives = 87/206 (42%), Gaps = 21/206 (10%) Query: 95 ELGQGNGGVVMKVRHKSTGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGA 154 ++G+G+ GV+ + ++A K + + + R K+L A I Y Sbjct: 17 KIGEGSFGVIFDGMNLLNNQLIAIKFEPKKSEAPQLRDEYRTYKLL--VGNAGIPNVY-Y 73 Query: 155 FYSDGEISICMEYMDGGSLDLILKKAGR-IPESILGTITSAVLKGLSYLRDKHAIMHRDV 213 F +G +I + + G SL+ + + GR + +L + + +K+ +++RD+ Sbjct: 74 FGQEGLHNILVIDLLGPSLEDLFEWCGRRFSVKTVAMTAKQMLSRVQTIHEKN-LVYRDI 132 Query: 214 KPSNILV------NSNGEIKICDFGVSGQLID---------SMANSFVGTRSYMSPERLQ 258 KP N L+ N+N + + DFG++ D S S GT YMS Sbjct: 133 KPDNFLIGRPSSRNAN-MVYMVDFGMAKYYRDPKTKQHIPYSERKSLSGTARYMSINTHL 191 Query: 259 GTHYSVQSDIWSLGLSLVEMAIGMYP 284 G S + D+ SLG + G P Sbjct: 192 GREQSRRDDLESLGHVFMYFLRGSLP 217 >SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizosaccharomyces pombe|chr 1|||Manual Length = 344 Score = 30.3 bits (65), Expect = 0.51 Identities = 37/144 (25%), Positives = 63/144 (43%), Gaps = 21/144 (14%) Query: 209 MHRDVKPSNILVNSNG-EIKICDFGVSGQLIDSMAN------------SFVGTRSYMSPE 255 +H D+KP N+L++ N EI + DFG S L+ A+ S T + +PE Sbjct: 191 IHGDIKPDNLLLHENSREIVLTDFG-SICLVPIFASNNSEAIAIQDKASENCTMPFRAPE 249 Query: 256 RLQ---GTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGGQNEDHS-PGQAPN 311 G+ + ++DIWS G +L + P ++ + N +S P + P Sbjct: 250 LFHVKAGSTITEKADIWSFGCTLYTIMFHASPFEREVSQGGSLALAVCNAQYSFPRKHPY 309 Query: 312 SPRPMAIFELLDYIVNEPPPKLPS 335 S + E+++ + P K PS Sbjct: 310 S---TLLCEIVEACLQREPNKRPS 330 >SPAC6G9.06c |pcp1||pericentrin Pcp1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1208 Score = 29.5 bits (63), Expect = 0.88 Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 3/88 (3%) Query: 38 ANERQGLAGKSKTSIEALTERLEQIEMDDTQRRRIEVFLCQKEKIGELSDDDFEKLGELG 97 +NE+Q L K + L ++ + + + L ++ KI S+DD EK E+ Sbjct: 704 SNEKQALELKYSSLKNELINAQNLLDRREEELSELSKKLFEERKIRSGSNDDIEKNKEIN 763 Query: 98 QGNGGVVMK---VRHKSTGLIMARKLIH 122 N + K +RH + + KL+H Sbjct: 764 VLNSELADKLAQIRHLESDKMELDKLVH 791 >SPAC15A10.13 |ppk3||serine/threonine protein kinase Ppk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 637 Score = 28.7 bits (61), Expect = 1.5 Identities = 16/41 (39%), Positives = 27/41 (65%), Gaps = 1/41 (2%) Query: 195 VLKGLSYLRDKHAIMHRDVKPSNILVNSNGEIKICDFGVSG 235 V LS+L DK+ I+H +++ S++ +NS E I DF ++G Sbjct: 122 VSAALSFLNDKN-IVHGNLQMSSVYLNSADEWIIGDFFLAG 161 >SPBC4C3.05c |nuc1|rpa1|DNA-directed RNA polymerase I complex large subunit Nuc1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1689 Score = 27.9 bits (59), Expect = 2.7 Identities = 12/34 (35%), Positives = 21/34 (61%) Query: 323 DYIVNEPPPKLPSGIFSDEFKDFVDRCLKKNPDE 356 D ++++ PP G S++F+ VD +KNPD+ Sbjct: 1122 DPVLDKYPPSRYLGSVSEKFQRAVDEYTQKNPDK 1155 >SPBC23G7.08c |rga7||GTPase activating protein Rga7|Schizosaccharomyces pombe|chr 2|||Manual Length = 695 Score = 27.9 bits (59), Expect = 2.7 Identities = 13/40 (32%), Positives = 23/40 (57%), Gaps = 3/40 (7%) Query: 15 PGSIDTNPAATPSNMTP---QLKSATANERQGLAGKSKTS 51 P S +NP+ P++ +P LK +TAN+ G + S ++ Sbjct: 388 PNSSTSNPSTAPASASPLASTLKPSTANDTNGSSSSSSSN 427 >SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 507 Score = 27.9 bits (59), Expect = 2.7 Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 247 GTRSYMSPERL-QGTHYSVQSDIWSLGLSLVEMAIGMYPI 285 GTR + +PE L + + S + DIWS G+ L+ +P+ Sbjct: 290 GTRGFRAPEVLFKCSSQSPKVDIWSAGVILLSFLTKRFPM 329 Score = 26.6 bits (56), Expect = 6.2 Identities = 12/28 (42%), Positives = 19/28 (67%), Gaps = 1/28 (3%) Query: 208 IMHRDVKPSNILVNSNGEIKI-CDFGVS 234 I+HRD+KPSN L + + + DFG++ Sbjct: 212 IIHRDIKPSNFLFDVRTKHGVLVDFGLA 239 >SPAC4F10.05c |||mitochondrial lipoate-protein ligase |Schizosaccharomyces pombe|chr 1|||Manual Length = 219 Score = 27.1 bits (57), Expect = 4.7 Identities = 11/21 (52%), Positives = 13/21 (61%) Query: 288 PDAKTLAAIFGGQNEDHSPGQ 308 P AK + A+ GGQ H PGQ Sbjct: 74 PKAKVVKALRGGQTTFHGPGQ 94 >SPBC1826.01c |mot1||TATA-binding protein associated factor Mot1|Schizosaccharomyces pombe|chr 2|||Manual Length = 1953 Score = 27.1 bits (57), Expect = 4.7 Identities = 30/93 (32%), Positives = 39/93 (41%), Gaps = 13/93 (13%) Query: 63 EMDDTQRRRIEVFLCQKEKIGELSDDDFEKLGELGQGNGGVVMKVRHKSTGLIMARK--- 119 +M D QR+ + F+ Q EL DD+ EK QG + H L RK Sbjct: 1613 DMSDLQRKLLNDFVSQLNINEELEDDETEKT----QGTRKKKSQKAHIFQALQYMRKLCN 1668 Query: 120 ---LIHLEVKP---AIKKQIIRELKVLHECNFA 146 LI E P AI KQ+ +E LH+ A Sbjct: 1669 HPALILTEKHPKRNAIVKQLAKENSGLHDLKHA 1701 >SPBC1734.15 |rsc4|brd1|RSC complex subunit Rsc4|Schizosaccharomyces pombe|chr 2|||Manual Length = 542 Score = 26.6 bits (56), Expect = 6.2 Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 7/96 (7%) Query: 15 PGSIDTNPAATPSNMTPQLKSATANERQ-GLAGKSKTSIEALTERLEQIEMDDTQRRRIE 73 P + P TP++ TP + ++T+ ER +A TS +A T ++ ++ +E Sbjct: 258 PATSKHEPEETPASPTPSVSASTSRERSTSVAPSFITSDQAATP-----DVLKSEEAHVE 312 Query: 74 VFLCQKEK-IGELSDDDFEKLGELGQGNGGVVMKVR 108 F + EK + +D + L Q N G ++ Sbjct: 313 SFSKESEKDQTPIPEDVPSPMDTLSQANYGAFALIK 348 >SPBPJ4664.02 |||glycoprotein |Schizosaccharomyces pombe|chr 2|||Manual Length = 3971 Score = 26.2 bits (55), Expect = 8.2 Identities = 15/56 (26%), Positives = 26/56 (46%) Query: 1 MSKMSKNKLNLTLPPGSIDTNPAATPSNMTPQLKSATANERQGLAGKSKTSIEALT 56 + K+ + ++LTL SI TPS MT S T + ++ S ++ L+ Sbjct: 3772 LGKIGSSSISLTLSSSSIRDAELPTPSRMTSPSLSETIPQSSSISEASTSNPNILS 3827 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.316 0.134 0.391 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,958,853 Number of Sequences: 5004 Number of extensions: 85665 Number of successful extensions: 572 Number of sequences better than 10.0: 109 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 270 Number of HSP's gapped (non-prelim): 180 length of query: 403 length of database: 2,362,478 effective HSP length: 74 effective length of query: 329 effective length of database: 1,992,182 effective search space: 655427878 effective search space used: 655427878 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 55 (26.2 bits)
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