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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001438-TA|BGIBMGA001438-PA|IPR009730|Micro-fibrillar-
associated 1, C-terminal
         (441 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC050742-1|AAH50742.1|  439|Homo sapiens microfibrillar-associat...   311   4e-84
BC023557-1|AAH23557.1|  439|Homo sapiens microfibrillar-associat...   311   4e-84
U04209-1|AAA92786.1|  439|Homo sapiens associated microfibrillar...   309   1e-83
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.          31   8.1  
EF212155-1|ABN05231.1|  391|Homo sapiens cellular titin isoform ...    31   8.1  
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.                31   8.1  

>BC050742-1|AAH50742.1|  439|Homo sapiens microfibrillar-associated
           protein 1 protein.
          Length = 439

 Score =  311 bits (763), Expect = 4e-84
 Identities = 182/447 (40%), Positives = 242/447 (54%), Gaps = 25/447 (5%)

Query: 2   NVLPAQPTGIQSTAGAIPIRNEKGEISMQKVKVQRYISGKKPDYAQGMXXXXXXXXXXFI 61
           + L  QP  IQSTAGA+P+RNEKGEISM+KVKV+RY+SGK+PDYA             FI
Sbjct: 5   SALMKQPP-IQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFI 63

Query: 62  EQQRPERKQVLPQIITRKEEHHSDSEKEVDDPRLRRLRN-IAQSPPRR-AEHK----PEI 115
           ++ + +  +         EE   DS     DPRLRRL+N I++    R A H+    PE+
Sbjct: 64  KKAKEQEAE--------PEEQEEDSSS---DPRLRRLQNRISEDVEERLARHRKIVEPEV 112

Query: 116 I-DAEPEAESEIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLGRXXXXX 174
           + +++ E E +                                        +        
Sbjct: 113 VGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDE 172

Query: 175 XXXXXXXXSGSSDTEYTDSEEDTGPRVKPVFVRASERMTVAERERKMXXXXXXXXXXXXX 234
                   S S   EYTDSE++  PR+KPVF+R  +R+TV ERE +              
Sbjct: 173 GRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRM 232

Query: 235 XXXXXXXXXXXXXXTIRSEQRGAQGEQKEGNINDVCTDDENDELEYEAWKLXXXXXXXXX 294
                           + E    + ++    ++ + TDDENDE EYEAWK+         
Sbjct: 233 AEERRKYTLKIVEEETKKELE--ENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRD 290

Query: 295 XXXXXXXXXXXLTLERLRNMTEDERRLEQRINPKVVTNKAVKGKYKFLQKYYHRGAFYLD 354
                        +ER+RN+TE+ERR E R N KV+TNKAVKGKYKFLQKYYHRGAF++D
Sbjct: 291 REDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMD 350

Query: 355 KEEDVFKQDFSGPTLDDHFDKTVLPKVMQVKKFGRSGRTKYTHLVDQDTTEFDSAWSNET 414
           ++E+V+K+DFS PTL+DHF+KT+LPKVMQVK FGRSGRTKYTHLVDQDTT FDSAW  E 
Sbjct: 351 EDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQE- 409

Query: 415 SAARLTNFR---GGMKQVFEKPSAERK 438
           SA     F+    G++ VFE+PSA+++
Sbjct: 410 SAQNTKFFKQKAAGVRDVFERPSAKKR 436


>BC023557-1|AAH23557.1|  439|Homo sapiens microfibrillar-associated
           protein 1 protein.
          Length = 439

 Score =  311 bits (763), Expect = 4e-84
 Identities = 182/447 (40%), Positives = 242/447 (54%), Gaps = 25/447 (5%)

Query: 2   NVLPAQPTGIQSTAGAIPIRNEKGEISMQKVKVQRYISGKKPDYAQGMXXXXXXXXXXFI 61
           + L  QP  IQSTAGA+P+RNEKGEISM+KVKV+RY+SGK+PDYA             FI
Sbjct: 5   SALMKQPP-IQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFI 63

Query: 62  EQQRPERKQVLPQIITRKEEHHSDSEKEVDDPRLRRLRN-IAQSPPRR-AEHK----PEI 115
           ++ + +  +         EE   DS     DPRLRRL+N I++    R A H+    PE+
Sbjct: 64  KKAKEQEAE--------PEEQEEDSSS---DPRLRRLQNRISEDVEERLARHRKIVEPEV 112

Query: 116 I-DAEPEAESEIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLGRXXXXX 174
           + +++ E E +                                        +        
Sbjct: 113 VGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDE 172

Query: 175 XXXXXXXXSGSSDTEYTDSEEDTGPRVKPVFVRASERMTVAERERKMXXXXXXXXXXXXX 234
                   S S   EYTDSE++  PR+KPVF+R  +R+TV ERE +              
Sbjct: 173 GRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRM 232

Query: 235 XXXXXXXXXXXXXXTIRSEQRGAQGEQKEGNINDVCTDDENDELEYEAWKLXXXXXXXXX 294
                           + E    + ++    ++ + TDDENDE EYEAWK+         
Sbjct: 233 AEERRKYTLKIVEEETKKELE--ENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRD 290

Query: 295 XXXXXXXXXXXLTLERLRNMTEDERRLEQRINPKVVTNKAVKGKYKFLQKYYHRGAFYLD 354
                        +ER+RN+TE+ERR E R N KV+TNKAVKGKYKFLQKYYHRGAF++D
Sbjct: 291 REDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMD 350

Query: 355 KEEDVFKQDFSGPTLDDHFDKTVLPKVMQVKKFGRSGRTKYTHLVDQDTTEFDSAWSNET 414
           ++E+V+K+DFS PTL+DHF+KT+LPKVMQVK FGRSGRTKYTHLVDQDTT FDSAW  E 
Sbjct: 351 EDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQE- 409

Query: 415 SAARLTNFR---GGMKQVFEKPSAERK 438
           SA     F+    G++ VFE+PSA+++
Sbjct: 410 SAQNTKFFKQKAAGVRDVFERPSAKKR 436


>U04209-1|AAA92786.1|  439|Homo sapiens associated microfibrillar
           protein protein.
          Length = 439

 Score =  309 bits (759), Expect = 1e-83
 Identities = 182/447 (40%), Positives = 241/447 (53%), Gaps = 25/447 (5%)

Query: 2   NVLPAQPTGIQSTAGAIPIRNEKGEISMQKVKVQRYISGKKPDYAQGMXXXXXXXXXXFI 61
           + L  QP  IQSTAGA+P+RNEKGEISM+KVKV+RY+SGK+PDYA             FI
Sbjct: 5   SALMKQPP-IQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFI 63

Query: 62  EQQRPERKQVLPQIITRKEEHHSDSEKEVDDPRLRRLRN-IAQSPPRR-AEHK----PEI 115
           ++ + +  +         EE   DS     DPRLRRL+N I++    R A H+    PE+
Sbjct: 64  KKAKEQEAE--------PEEQEEDSSS---DPRLRRLQNRISEDVEERLARHRKIVEPEV 112

Query: 116 I-DAEPEAESEIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLGRXXXXX 174
           + +++ E E +                                        +        
Sbjct: 113 VGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDE 172

Query: 175 XXXXXXXXSGSSDTEYTDSEEDTGPRVKPVFVRASERMTVAERERKMXXXXXXXXXXXXX 234
                   S S   EYTDSE++  PR+KPVF+R  +R+TV ERE +              
Sbjct: 173 GRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRM 232

Query: 235 XXXXXXXXXXXXXXTIRSEQRGAQGEQKEGNINDVCTDDENDELEYEAWKLXXXXXXXXX 294
                             E    + ++    ++ + TDDENDE EYEAWK+         
Sbjct: 233 AEERRQYTLQIVGEETPKELE--ENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRD 290

Query: 295 XXXXXXXXXXXLTLERLRNMTEDERRLEQRINPKVVTNKAVKGKYKFLQKYYHRGAFYLD 354
                        +ER+RN+TE+ERR E R N KV+TNKAVKGKYKFLQKYYHRGAF++D
Sbjct: 291 REDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMD 350

Query: 355 KEEDVFKQDFSGPTLDDHFDKTVLPKVMQVKKFGRSGRTKYTHLVDQDTTEFDSAWSNET 414
           ++E+V+K+DFS PTL+DHF+KT+LPKVMQVK FGRSGRTKYTHLVDQDTT FDSAW  E 
Sbjct: 351 EDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQE- 409

Query: 415 SAARLTNFR---GGMKQVFEKPSAERK 438
           SA     F+    G++ VFE+PSA+++
Sbjct: 410 SAQNTKFFKQKAAGVRDVFERPSAKKR 436


>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
          Length = 7962

 Score = 31.1 bits (67), Expect = 8.1
 Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 12/72 (16%)

Query: 61   IEQQR---PERKQVLPQIITRKEEHHSDSEKEV--DDPRLRRLRNIAQSPPRRAEHKPEI 115
            +E++R   P+ ++VLP  +T + E    SE+E+  + P +  +  +A  PPR     PE+
Sbjct: 6884 VEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVA--PPR----VPEV 6937

Query: 116  I-DAEPEAESEI 126
            I  A PEA + +
Sbjct: 6938 IKKAVPEAPTPV 6949


>EF212155-1|ABN05231.1|  391|Homo sapiens cellular titin isoform
           PEVK variant 3 protein.
          Length = 391

 Score = 31.1 bits (67), Expect = 8.1
 Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 12/72 (16%)

Query: 61  IEQQR---PERKQVLPQIITRKEEHHSDSEKEV--DDPRLRRLRNIAQSPPRRAEHKPEI 115
           +E++R   P+ ++VLP  +T + E    SE+E+  + P +  +  +A  PPR     PE+
Sbjct: 289 VEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVA--PPR----VPEV 342

Query: 116 I-DAEPEAESEI 126
           I  A PEA + +
Sbjct: 343 IKKAVPEAPTPV 354


>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
          Length = 30000

 Score = 31.1 bits (67), Expect = 8.1
 Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 12/72 (16%)

Query: 61    IEQQR---PERKQVLPQIITRKEEHHSDSEKEV--DDPRLRRLRNIAQSPPRRAEHKPEI 115
             +E++R   P+ ++VLP  +T + E    SE+E+  + P +  +  +A  PPR     PE+
Sbjct: 11146 VEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVA--PPR----VPEV 11199

Query: 116   I-DAEPEAESEI 126
             I  A PEA + +
Sbjct: 11200 IKKAVPEAPTPV 11211


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.312    0.130    0.365 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 48,472,885
Number of Sequences: 224733
Number of extensions: 1651731
Number of successful extensions: 3584
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3560
Number of HSP's gapped (non-prelim): 15
length of query: 441
length of database: 73,234,838
effective HSP length: 92
effective length of query: 349
effective length of database: 52,559,402
effective search space: 18343231298
effective search space used: 18343231298
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.9 bits)
S2: 67 (31.1 bits)

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