Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001436-TA|BGIBMGA001436-PA|IPR001611|Leucine-rich
repeat, IPR003591|Leucine-rich repeat, typical subtype
(410 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY052405-1|AAL11430.1| 414|Homo sapiens 4-1BB-mediated signalin... 224 4e-58
BC139921-1|AAI39922.1| 414|Homo sapiens peptidylprolyl isomeras... 222 2e-57
BC112241-1|AAI12242.1| 146|Homo sapiens peptidylprolyl isomeras... 81 5e-15
BC107888-1|AAI07889.1| 146|Homo sapiens peptidylprolyl isomeras... 81 5e-15
BC093697-1|AAH93697.1| 146|Homo sapiens peptidylprolyl isomeras... 81 5e-15
BC030142-1|AAH30142.1| 146|Homo sapiens peptidylprolyl isomeras... 81 5e-15
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 75 3e-13
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 75 3e-13
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 75 3e-13
AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens ... 75 3e-13
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 75 3e-13
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 75 3e-13
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 75 5e-13
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 75 5e-13
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 75 5e-13
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 75 5e-13
D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein. 74 8e-13
AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein. 74 8e-13
AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein. 74 8e-13
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 72 3e-12
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 72 3e-12
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 72 3e-12
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 72 3e-12
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 72 3e-12
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 72 3e-12
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 72 3e-12
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 72 3e-12
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 72 3e-12
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 72 3e-12
BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein. 69 2e-11
AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein. 69 2e-11
BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting prote... 68 5e-11
BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting prote... 68 5e-11
BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein. 68 5e-11
AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats an... 68 5e-11
AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats an... 68 5e-11
AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein... 68 5e-11
AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein. 68 5e-11
AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting prote... 68 5e-11
AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein. 68 5e-11
BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein. 68 7e-11
BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein. 68 7e-11
AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isofor... 68 7e-11
AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isofor... 68 7e-11
AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein. 68 7e-11
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 67 1e-10
BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat con... 67 1e-10
AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein. 67 1e-10
AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat con... 67 1e-10
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 67 1e-10
AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens ... 67 1e-10
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 67 1e-10
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 67 1e-10
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 67 1e-10
BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein. 65 4e-10
BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats an... 65 4e-10
AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein. 65 4e-10
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 65 5e-10
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 65 5e-10
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 65 5e-10
AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat con... 65 5e-10
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 65 5e-10
BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat con... 64 6e-10
AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein. 64 6e-10
AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar t... 64 6e-10
L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein. 63 1e-09
CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein. 63 1e-09
CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein. 63 1e-09
BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein. 63 1e-09
BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein. 63 1e-09
BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein. 63 1e-09
BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat con... 63 1e-09
BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein ... 63 1e-09
BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat con... 63 1e-09
BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein. 63 1e-09
BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein ... 63 1e-09
AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein. 63 1e-09
AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat con... 63 1e-09
AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat con... 63 1e-09
AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein ... 63 1e-09
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 63 1e-09
AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens ... 63 1e-09
AL391728-3|CAH73693.1| 217|Homo sapiens leucine rich repeat con... 63 2e-09
AL359894-1|CAH73131.1| 217|Homo sapiens leucine rich repeat con... 63 2e-09
AL359412-3|CAH74020.1| 217|Homo sapiens leucine rich repeat con... 63 2e-09
AL117353-2|CAI23424.1| 217|Homo sapiens leucine rich repeat con... 63 2e-09
AF498274-1|AAP06801.1| 217|Homo sapiens densin-180 like protein... 63 2e-09
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 62 3e-09
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 62 3e-09
AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens ... 62 3e-09
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 62 3e-09
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 62 5e-09
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 62 5e-09
AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein ... 60 1e-08
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 60 2e-08
BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats an... 59 2e-08
BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and... 59 2e-08
AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein pr... 59 2e-08
AL445222-17|CAH72930.1| 723|Homo sapiens leucine rich repeat an... 59 2e-08
AL445222-16|CAH72931.1| 696|Homo sapiens leucine rich repeat an... 59 2e-08
AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal p... 59 2e-08
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin... 59 3e-08
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin... 59 3e-08
AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat con... 58 4e-08
BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat con... 57 1e-07
BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat con... 57 1e-07
AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and... 57 1e-07
AY358137-1|AAQ88504.1| 255|Homo sapiens VKGE9338 protein. 57 1e-07
AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich repeat-con... 57 1e-07
BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat con... 56 2e-07
AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat con... 56 2e-07
AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens ... 56 2e-07
BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat con... 56 2e-07
BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat con... 56 2e-07
AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein. 56 2e-07
AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich repeat-con... 56 2e-07
AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat con... 56 2e-07
AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat con... 56 2e-07
AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein. 56 2e-07
BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein. 56 3e-07
AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens ... 56 3e-07
BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte di... 55 5e-07
AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein. 55 5e-07
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 54 7e-07
D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein. 54 1e-06
BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein. 54 1e-06
BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat con... 54 1e-06
BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein. 54 1e-06
BC036722-1|AAH36722.1| 261|Homo sapiens leucine rich repeat con... 54 1e-06
BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat con... 54 1e-06
BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein. 54 1e-06
AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein pr... 54 1e-06
AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens ... 54 1e-06
AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens ... 54 1e-06
AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leuci... 54 1e-06
AB033020-1|BAA86508.1| 575|Homo sapiens KIAA1194 protein protein. 54 1e-06
BC007504-1|AAH07504.1| 712|Homo sapiens leucine-rich repeats an... 53 2e-06
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 53 2e-06
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 53 2e-06
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 53 2e-06
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 53 2e-06
BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein. 52 4e-06
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 52 4e-06
AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats an... 52 4e-06
AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats an... 52 4e-06
AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats an... 52 4e-06
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 52 4e-06
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 52 4e-06
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 52 4e-06
AK058188-1|BAB71707.1| 475|Homo sapiens protein ( Homo sapiens ... 52 5e-06
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 51 6e-06
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 51 9e-06
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 51 9e-06
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 51 9e-06
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 50 1e-05
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 50 1e-05
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 50 1e-05
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 49 3e-05
BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein. 49 3e-05
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 49 3e-05
BC026112-1|AAH26112.1| 116|Homo sapiens hypothetical protein LO... 49 3e-05
AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein. 48 5e-05
AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein. 48 5e-05
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 48 6e-05
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 48 6e-05
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 48 6e-05
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 48 6e-05
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 48 6e-05
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 48 6e-05
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 48 8e-05
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 48 8e-05
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 48 8e-05
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 48 8e-05
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 48 8e-05
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 48 8e-05
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 48 8e-05
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 48 8e-05
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 48 8e-05
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 48 8e-05
DQ013130-1|AAY67799.1| 2014|Homo sapiens leucine-rich repeat kin... 47 1e-04
DQ355157-1|ABC79623.1| 334|Homo sapiens cytokeratin associated ... 47 1e-04
BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein. 47 1e-04
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 47 1e-04
AL929554-11|CAH72880.1| 334|Homo sapiens leucine rich repeat co... 47 1e-04
BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine r... 46 2e-04
AK127729-1|BAC87105.1| 870|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein. 46 2e-04
BC050097-1|AAH50097.1| 383|Homo sapiens LRRC27 protein protein. 46 2e-04
AL590105-6|CAI13017.1| 530|Homo sapiens novel protein protein. 46 2e-04
AL590105-5|CAI13016.1| 383|Homo sapiens novel protein protein. 46 2e-04
AK098652-1|BAC05366.1| 383|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AB051461-1|BAB21765.1| 538|Homo sapiens KIAA1674 protein protein. 46 2e-04
BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein. 46 3e-04
AY358298-1|AAQ88665.1| 598|Homo sapiens CSRV314 protein. 46 3e-04
AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich... 46 3e-04
AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich... 46 3e-04
X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin gl... 45 4e-04
X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin gl... 45 4e-04
M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin gl... 45 4e-04
BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein. 45 4e-04
BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin ... 45 4e-04
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 45 4e-04
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 45 4e-04
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 45 4e-04
AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin ... 45 4e-04
AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens ... 45 4e-04
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 45 4e-04
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 45 4e-04
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 44 7e-04
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 44 7e-04
BC030547-1|AAH30547.1| 647|Homo sapiens hypothetical protein DK... 44 7e-04
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 44 0.001
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 44 0.001
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 44 0.001
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 44 0.001
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 44 0.001
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 44 0.001
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 44 0.001
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 44 0.001
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 44 0.001
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 44 0.001
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 44 0.001
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 44 0.001
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 44 0.001
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 44 0.001
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 44 0.001
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 44 0.001
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 44 0.001
BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein. 44 0.001
BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with ... 44 0.001
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 44 0.001
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 44 0.001
AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor ... 44 0.001
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 44 0.001
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 44 0.001
AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein A... 44 0.001
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 44 0.001
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 44 0.001
AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein. 44 0.001
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 44 0.001
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 44 0.001
BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein. 43 0.002
AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein. 43 0.002
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 43 0.002
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 43 0.002
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 43 0.002
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 43 0.002
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 43 0.002
AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein. 43 0.002
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 43 0.002
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 43 0.002
AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein. 43 0.002
AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein. 43 0.002
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 43 0.002
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 43 0.002
BC114551-1|AAI14552.1| 334|Homo sapiens ISLR2 protein protein. 42 0.003
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 42 0.003
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 42 0.003
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 42 0.004
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 42 0.004
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 42 0.004
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 42 0.004
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 42 0.004
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 42 0.004
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 42 0.004
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 42 0.004
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 42 0.004
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 42 0.004
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 42 0.005
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 42 0.005
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 42 0.005
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 42 0.005
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 42 0.005
BC064133-1|AAH64133.1| 64|Homo sapiens PPIL5 protein protein. 41 0.007
AK130975-1|BAC85472.1| 209|Homo sapiens protein ( Homo sapiens ... 41 0.007
AB209379-1|BAD92616.1| 245|Homo sapiens hypothetical protein DK... 41 0.007
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 41 0.009
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 41 0.009
BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with ... 41 0.009
AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein A... 41 0.009
AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with ... 41 0.009
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 41 0.009
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 41 0.009
AB051551-1|BAB21855.1| 1029|Homo sapiens KIAA1764 protein protein. 41 0.009
AB032989-1|BAA86477.1| 437|Homo sapiens KIAA1163 protein protein. 41 0.009
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 40 0.012
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 40 0.012
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 40 0.012
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 40 0.012
BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats an... 40 0.016
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 40 0.016
AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein. 40 0.016
U88540-1|AAC34137.1| 786|Homo sapiens Toll-like receptor 1 prot... 40 0.021
D13637-1|BAA02801.2| 789|Homo sapiens KIAA0012 protein. 40 0.021
CR533562-1|CAG38593.1| 786|Homo sapiens TLR1 protein. 40 0.021
BC109094-1|AAI09095.1| 786|Homo sapiens toll-like receptor 1 pr... 40 0.021
BC109093-1|AAI09094.1| 786|Homo sapiens toll-like receptor 1 pr... 40 0.021
BC089403-1|AAH89403.1| 786|Homo sapiens toll-like receptor 1 pr... 40 0.021
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 39 0.028
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 39 0.028
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 39 0.028
AB020807-1|BAA78631.1| 796|Homo sapiens TLR6 protein. 39 0.028
BC101077-1|AAI01078.1| 1041|Homo sapiens toll-like receptor 8 pr... 39 0.037
BC101076-1|AAI01077.1| 1041|Homo sapiens toll-like receptor 8 pr... 39 0.037
BC101075-1|AAI01076.1| 1041|Homo sapiens toll-like receptor 8 pr... 39 0.037
BC101074-1|AAI01075.1| 1041|Homo sapiens toll-like receptor 8 pr... 39 0.037
BC040732-1|AAH40732.1| 269|Homo sapiens LRTM1 protein protein. 39 0.037
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 39 0.037
AY358296-1|AAQ88663.1| 1041|Homo sapiens TLR8 protein. 39 0.037
AF246971-1|AAF64061.1| 1059|Homo sapiens Toll-like receptor 8 pr... 39 0.037
AF245703-1|AAF78036.1| 1041|Homo sapiens toll-like receptor 8 pr... 39 0.037
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 39 0.037
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 38 0.049
BC074943-1|AAH74943.1| 332|Homo sapiens opticin protein. 38 0.049
BC074942-1|AAH74942.1| 332|Homo sapiens opticin protein. 38 0.049
BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for IM... 38 0.049
AY077681-1|AAL78286.1| 332|Homo sapiens opticin protein. 38 0.049
AL391817-3|CAI17035.1| 332|Homo sapiens opticin protein. 38 0.049
AK127177-1|BAC86870.1| 279|Homo sapiens protein ( Homo sapiens ... 38 0.049
AJ133790-1|CAB53459.1| 332|Homo sapiens opticin protein. 38 0.049
AF161702-1|AAD45900.1| 332|Homo sapiens oculoglycan protein. 38 0.049
BC035645-1|AAH35645.1| 1266|Homo sapiens Similar to RIKEN cDNA 3... 38 0.064
BC009436-1|AAH09436.1| 610|Homo sapiens Unknown (protein for IM... 38 0.064
AY358306-1|AAQ88673.1| 616|Homo sapiens GPR125 protein. 38 0.064
AB033011-1|BAA86499.1| 403|Homo sapiens KIAA1185 protein protein. 38 0.064
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 38 0.085
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 38 0.085
CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein. 38 0.085
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 38 0.085
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 38 0.085
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 38 0.085
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 38 0.085
BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein. 38 0.085
BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat neu... 38 0.085
BC030701-1|AAH30701.3| 933|Homo sapiens LRRCC1 protein protein. 38 0.085
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 38 0.085
AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein. 38 0.085
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 38 0.085
AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat pro... 38 0.085
AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich r... 38 0.085
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 37 0.11
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 37 0.11
BX538330-1|CAD98099.1| 358|Homo sapiens hypothetical protein pr... 37 0.11
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 37 0.11
AL590105-8|CAI13019.1| 468|Homo sapiens novel protein protein. 37 0.11
AL590105-7|CAI13018.1| 257|Homo sapiens novel protein protein. 37 0.11
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 37 0.11
AK093250-1|BAC04108.1| 468|Homo sapiens protein ( Homo sapiens ... 37 0.11
AB209529-1|BAD92766.1| 751|Homo sapiens leucine rich repeat and... 37 0.11
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 37 0.15
BT007440-1|AAP36108.1| 353|Homo sapiens hypothetical protein, e... 37 0.15
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 37 0.15
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 37 0.15
BC020975-1|AAH20975.1| 353|Homo sapiens tsukushin protein. 37 0.15
AY358317-1|AAQ88683.1| 353|Homo sapiens E2IG4 protein. 37 0.15
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 37 0.15
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 37 0.15
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 37 0.15
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 37 0.15
BC119649-1|AAI19650.1| 257|Homo sapiens leucine rich repeat con... 36 0.20
BC119648-1|AAI19649.1| 257|Homo sapiens leucine rich repeat con... 36 0.20
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 36 0.20
AY358120-1|AAQ88487.1| 257|Homo sapiens LLR protein protein. 36 0.20
AY061857-1|AAL35741.1| 257|Homo sapiens leucine-rich repeat dom... 36 0.20
AF191019-1|AAF09483.1| 353|Homo sapiens E2IG4 protein. 36 0.20
AB058646-1|BAB40229.1| 257|Homo sapiens LRRC3 protein. 36 0.20
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 36 0.26
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 36 0.26
BC024001-1|AAH24001.1| 184|Homo sapiens leucine rich repeat con... 36 0.26
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 36 0.26
AY358318-1|AAQ88684.1| 184|Homo sapiens LKKM2429 protein. 36 0.26
AL355138-4|CAI12602.1| 175|Homo sapiens leucine rich repeat con... 36 0.26
AL355138-2|CAI12600.1| 184|Homo sapiens leucine rich repeat con... 36 0.26
AK094734-1|BAC04409.1| 184|Homo sapiens protein ( Homo sapiens ... 36 0.26
AK091588-1|BAC03702.1| 213|Homo sapiens protein ( Homo sapiens ... 36 0.26
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 36 0.26
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 36 0.34
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 36 0.34
BC111755-1|AAI11756.1| 480|Homo sapiens TLR6 protein protein. 36 0.34
BC109111-1|AAI09112.1| 811|Homo sapiens TLR10 protein protein. 36 0.34
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 36 0.34
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 36 0.34
BC089406-1|AAH89406.1| 811|Homo sapiens TLR10 protein protein. 36 0.34
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 36 0.34
AY358300-1|AAQ88667.1| 811|Homo sapiens TLR10 protein. 36 0.34
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 36 0.34
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 36 0.34
AF296673-1|AAK26744.1| 811|Homo sapiens toll-like receptor 10 p... 36 0.34
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 36 0.34
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 36 0.34
AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix pr... 36 0.34
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 35 0.45
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 35 0.45
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 35 0.45
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 35 0.45
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 35 0.45
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 35 0.45
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 35 0.45
AL833849-1|CAD38708.1| 633|Homo sapiens hypothetical protein pr... 35 0.45
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 35 0.45
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 35 0.45
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 35 0.45
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 35 0.45
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 35 0.45
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 35 0.45
AB208832-1|BAD92069.1| 680|Homo sapiens Hypothetical protein DK... 35 0.45
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 35 0.45
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 35 0.60
AF177766-1|AAF07823.1| 752|Homo sapiens human toll-like recepto... 35 0.60
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 35 0.60
U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3 prot... 34 0.79
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 34 0.79
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 34 0.79
M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane glycopr... 34 0.79
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 34 0.79
J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein. 34 0.79
DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3 is... 34 0.79
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 34 0.79
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 34 0.79
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 34 0.79
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 34 0.79
BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein. 34 0.79
BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3 pr... 34 0.79
BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3 pr... 34 0.79
BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3 pr... 34 0.79
BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3 pr... 34 0.79
BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein. 34 0.79
BC047653-1|AAH47653.1| 656|Homo sapiens PHLPP protein protein. 34 0.79
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 34 0.79
BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib (platel... 34 0.79
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 34 0.79
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 34 0.79
AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein I... 34 0.79
AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5 pr... 34 0.79
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 34 0.79
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 34 0.79
AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib (platel... 34 0.79
AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1 rece... 34 0.79
AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein I... 34 0.79
AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5 pr... 34 0.79
AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein I... 34 0.79
AL355138-5|CAI12601.1| 134|Homo sapiens leucine rich repeat con... 34 1.0
AK001706-1|BAA91849.1| 184|Homo sapiens protein ( Homo sapiens ... 34 1.0
Y08200-1|CAA69382.1| 567|Homo sapiens rab geranylgeranyl transf... 33 1.4
CR541797-1|CAG46596.1| 567|Homo sapiens RABGGTA protein. 33 1.4
BC109112-1|AAI09113.1| 811|Homo sapiens TLR10 protein protein. 33 1.4
BC003093-1|AAH03093.1| 567|Homo sapiens Rab geranylgeranyltrans... 33 1.4
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 33 1.8
BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like fami... 33 1.8
BC104037-1|AAI04038.1| 552|Homo sapiens FLJ44691 protein protein. 33 1.8
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 33 1.8
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 33 1.8
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 33 1.8
AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein. 33 1.8
U21128-1|AAA91639.1| 338|Homo sapiens lumican protein. 33 2.4
U18728-1|AAA85268.1| 338|Homo sapiens lumican protein. 33 2.4
BT006707-1|AAP35353.1| 338|Homo sapiens lumican protein. 33 2.4
BC035997-1|AAH35997.1| 338|Homo sapiens lumican protein. 33 2.4
BC030958-1|AAH30958.1| 322|Homo sapiens epiphycan protein. 33 2.4
BC007038-1|AAH07038.1| 338|Homo sapiens lumican protein. 33 2.4
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 33 2.4
AK223177-1|BAD96897.1| 338|Homo sapiens lumican variant protein. 33 2.4
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 33 2.4
AK128037-1|BAC87242.1| 1111|Homo sapiens protein ( Homo sapiens ... 33 2.4
U88881-1|AAC34136.1| 365|Homo sapiens Toll-like receptor 5 prot... 32 3.2
L43619-1|AAC41765.1| 4292|Homo sapiens polycystic kidney disease... 32 3.2
L39891-1|AAB59488.1| 3638|Homo sapiens polycystic kidney disease... 32 3.2
L33243-1|AAC37576.1| 4302|Homo sapiens polycystic kidney disease... 32 3.2
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 32 3.2
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 32 3.2
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 32 3.2
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 32 3.2
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 32 3.2
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 32 3.2
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 32 3.2
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 32 4.2
BC001354-1|AAH01354.1| 259|Homo sapiens leucine rich repeat con... 32 4.2
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 32 4.2
AC005586-4|AAS00383.1| 259|Homo sapiens unknown protein. 32 4.2
U24497-1|AAC50128.1| 4303|Homo sapiens autosomal dominant polycy... 31 5.6
AK027100-1|BAB15657.1| 363|Homo sapiens protein ( Homo sapiens ... 31 5.6
AB031547-1|BAA95681.1| 623|Homo sapiens retina specific protein... 31 5.6
U88878-1|AAC34133.1| 784|Homo sapiens Toll-like receptor 2 prot... 31 7.4
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 31 7.4
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 31 7.4
BC050665-1|AAH50665.1| 523|Homo sapiens LRRC48 protein protein. 31 7.4
BC050419-1|AAH50419.1| 523|Homo sapiens LRRC48 protein protein. 31 7.4
BC047873-1|AAH47873.1| 523|Homo sapiens leucine rich repeat con... 31 7.4
BC040276-1|AAH40276.1| 457|Homo sapiens LRRC48 protein protein. 31 7.4
BC033756-1|AAH33756.1| 784|Homo sapiens TLR2 protein protein. 31 7.4
BC008782-1|AAH08782.1| 1219|Homo sapiens nuclear factor of kappa... 31 7.4
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 31 7.4
AF502291-1|AAM23001.1| 586|Homo sapiens toll-like receptor 2 pr... 31 7.4
>AY052405-1|AAL11430.1| 414|Homo sapiens 4-1BB-mediated signaling
molecule protein.
Length = 414
Score = 224 bits (548), Expect = 4e-58
Identities = 142/416 (34%), Positives = 224/416 (53%), Gaps = 17/416 (4%)
Query: 1 MKIQCQIEVINRLHSALNLRNNGKYLKSTLALGKEPKSE---TEYFILHFSSLNKTGTKY 57
MK+ C++EVI+R AL LRN GK ++S L+L ++ F+L + +K GT+Y
Sbjct: 1 MKLHCEVEVISRHLPALGLRNRGKVVRSVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRY 60
Query: 58 RVK-SIKQVFVKYINEGKSTIRFEEPPYDLCI-KSESIQLKCFMKLLRSCITGDEKALHL 115
++ +I+Q F K+++EGK+T+R +EPP D+C+ K+ S LK F+ +R G +
Sbjct: 61 ELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKAISSSLKGFLSAMRLAHRGCNVDTPV 120
Query: 116 SPLSSLSVTAKNNAPVKLVISDRSQFP-AKGLPRTLQSLYLSGLKLCNFRRDILLLKHLA 174
S L+ + + N K+VI+ + +P +K P +L+ L S L +L LK L
Sbjct: 121 STLTPVKTSEFENFKTKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLR 180
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
LDLS+N I+KLP G + +L EL+L +N L V L + K+L+ LDL+ N
Sbjct: 181 KLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVA----LCHSTLQKSLRSLDLSKN 236
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRL 294
K+ LP +L++L LK +DN + + P IG++ LR+ + + N+L LP L
Sbjct: 237 KIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSL 296
Query: 295 EYIDISSNKFDNKQNNSTSDQYSPWQFYVGSLVHLSAKIILKHKIHYASNIIPWTLVEFL 354
EY+D+ N F+ + +P +L+ SA+ IL ++I Y S+IIP+ L + L
Sbjct: 297 EYLDLFGNTFEQPKVLPVIKLQAPL-----TLLESSARTILHNRIPYGSHIIPFHLCQDL 351
Query: 355 DNANMCVCGAPVVNYTHSINKEYDLKDYFRTVVFNNNLSVVE--FECYFCSPKCFL 408
D A +CVCG +N +L TVV +NL E YFCS C++
Sbjct: 352 DTAKICVCGRFCLNSFIQGTTTMNLHSVAHTVVLVDNLGGTEAPIISYFCSLGCYV 407
>BC139921-1|AAI39922.1| 414|Homo sapiens peptidylprolyl isomerase
(cyclophilin)-like 5 protein.
Length = 414
Score = 222 bits (543), Expect = 2e-57
Identities = 141/416 (33%), Positives = 224/416 (53%), Gaps = 17/416 (4%)
Query: 1 MKIQCQIEVINRLHSALNLRNNGKYLKSTLALGKEPKSE---TEYFILHFSSLNKTGTKY 57
MK+ C++EVI+R AL LRN GK +++ L+L ++ F+L + +K GT+Y
Sbjct: 1 MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRY 60
Query: 58 RVK-SIKQVFVKYINEGKSTIRFEEPPYDLCI-KSESIQLKCFMKLLRSCITGDEKALHL 115
++ +I+Q F K+++EGK+T+R +EPP D+C+ K+ S LK F+ +R G +
Sbjct: 61 ELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKAISSSLKGFLSAMRLAHRGCNVDTPV 120
Query: 116 SPLSSLSVTAKNNAPVKLVISDRSQFP-AKGLPRTLQSLYLSGLKLCNFRRDILLLKHLA 174
S L+ + + N K+VI+ + +P +K P +L+ L S L +L LK L
Sbjct: 121 STLTPVKTSEFENFKTKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLR 180
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
LDLS+N I+KLP G + +L EL+L +N L V L + K+L+ LDL+ N
Sbjct: 181 KLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVA----LCHSTLQKSLRSLDLSKN 236
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRL 294
K+ LP +L++L LK +DN + + P IG++ LR+ + + N+L LP L
Sbjct: 237 KIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNLSL 296
Query: 295 EYIDISSNKFDNKQNNSTSDQYSPWQFYVGSLVHLSAKIILKHKIHYASNIIPWTLVEFL 354
EY+D+ N F+ + +P +L+ SA+ IL ++I Y S+IIP+ L + L
Sbjct: 297 EYLDLFGNTFEQPKVLPVIKLQAPL-----TLLESSARTILHNRIPYGSHIIPFHLCQDL 351
Query: 355 DNANMCVCGAPVVNYTHSINKEYDLKDYFRTVVFNNNLSVVE--FECYFCSPKCFL 408
D A +CVCG +N +L TVV +NL E YFCS C++
Sbjct: 352 DTAKICVCGRFCLNSFIQGTTTMNLHSVAHTVVLVDNLGGTEAPIISYFCSLGCYV 407
>BC112241-1|AAI12242.1| 146|Homo sapiens peptidylprolyl isomerase
(cyclophilin)-like 5 protein.
Length = 146
Score = 81.4 bits (192), Expect = 5e-15
Identities = 39/99 (39%), Positives = 66/99 (66%), Gaps = 4/99 (4%)
Query: 1 MKIQCQIEVINRLHSALNLRNNGKYLKSTLALGKEPKSE---TEYFILHFSSLNKTGTKY 57
MK+ C++EVI+R AL LRN GK +++ L+L ++ F+L + +K GT+Y
Sbjct: 1 MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRY 60
Query: 58 RVK-SIKQVFVKYINEGKSTIRFEEPPYDLCIKSESIQL 95
++ +I+Q F K+++EGK+T+R +EPP D+C+ +SI L
Sbjct: 61 ELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKDSIWL 99
>BC107888-1|AAI07889.1| 146|Homo sapiens peptidylprolyl isomerase
(cyclophilin)-like 5 protein.
Length = 146
Score = 81.4 bits (192), Expect = 5e-15
Identities = 39/99 (39%), Positives = 66/99 (66%), Gaps = 4/99 (4%)
Query: 1 MKIQCQIEVINRLHSALNLRNNGKYLKSTLALGKEPKSE---TEYFILHFSSLNKTGTKY 57
MK+ C++EVI+R AL LRN GK +++ L+L ++ F+L + +K GT+Y
Sbjct: 1 MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRY 60
Query: 58 RVK-SIKQVFVKYINEGKSTIRFEEPPYDLCIKSESIQL 95
++ +I+Q F K+++EGK+T+R +EPP D+C+ +SI L
Sbjct: 61 ELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKDSIWL 99
>BC093697-1|AAH93697.1| 146|Homo sapiens peptidylprolyl isomerase
(cyclophilin)-like 5 protein.
Length = 146
Score = 81.4 bits (192), Expect = 5e-15
Identities = 39/99 (39%), Positives = 66/99 (66%), Gaps = 4/99 (4%)
Query: 1 MKIQCQIEVINRLHSALNLRNNGKYLKSTLALGKEPKSE---TEYFILHFSSLNKTGTKY 57
MK+ C++EVI+R AL LRN GK +++ L+L ++ F+L + +K GT+Y
Sbjct: 1 MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRY 60
Query: 58 RVK-SIKQVFVKYINEGKSTIRFEEPPYDLCIKSESIQL 95
++ +I+Q F K+++EGK+T+R +EPP D+C+ +SI L
Sbjct: 61 ELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKDSIWL 99
>BC030142-1|AAH30142.1| 146|Homo sapiens peptidylprolyl isomerase
(cyclophilin)-like 5 protein.
Length = 146
Score = 81.4 bits (192), Expect = 5e-15
Identities = 39/99 (39%), Positives = 66/99 (66%), Gaps = 4/99 (4%)
Query: 1 MKIQCQIEVINRLHSALNLRNNGKYLKSTLALGKEPKSE---TEYFILHFSSLNKTGTKY 57
MK+ C++EVI+R AL LRN GK +++ L+L ++ F+L + +K GT+Y
Sbjct: 1 MKLHCEVEVISRHLPALGLRNRGKGVRAVLSLCQQTSRSQPPVRAFLLISTLKDKRGTRY 60
Query: 58 RVK-SIKQVFVKYINEGKSTIRFEEPPYDLCIKSESIQL 95
++ +I+Q F K+++EGK+T+R +EPP D+C+ +SI L
Sbjct: 61 ELRENIEQFFTKFVDEGKATVRLKEPPVDICLSKDSIWL 99
>BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 8/160 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/171 (31%), Positives = 87/171 (50%), Gaps = 17/171 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN----- 204
L+ L+L G +L ++I LK+L LD+S N +E+LP E + +L++L ++ N
Sbjct: 199 LKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETI 258
Query: 205 --------QLGVRGVVDWRWLLGPQIT---KTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
+L + V R P+ ++L L LT N+L LPK+I KL+KL L
Sbjct: 259 PDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLN 318
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
A+ N + LP IG +L F + N L +P + Q L +D++ N+
Sbjct: 319 ADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNR 369
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L++L + N + +LP G +L+EL L NQL L I K KL
Sbjct: 265 LKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQL---------LTLPKSIGKLKKLS 315
Query: 230 DLTS--NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+L + NKL LPK I L DN ++R+PA + + + L ++ N L LP
Sbjct: 316 NLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL 375
Query: 288 SLMQCRLEYIDISSNKFDNKQNNSTSDQYS 317
SL +L+ + +S N+ T Y+
Sbjct: 376 SLTALKLKALWLSDNQSQPLLTFQTDTDYT 405
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 18/180 (10%)
Query: 133 LVISDRSQFPAKGLPRT------LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKL 186
L ++D S P LP + L L ++ + L + +I L +LA L+L N + L
Sbjct: 107 LQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYL 166
Query: 187 PPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIW 244
P ++ L EL L NN++ + L I L L DL N+L LP+ I
Sbjct: 167 PDSLTQLRRLEELDLGNNEI---------YNLPESIGALLHLKDLWLDGNQLSELPQEIG 217
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
L+ L+ L ++N + RLP I +++L IS N L+++P + + +L + + N+
Sbjct: 218 NLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNR 277
>AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 8/160 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/171 (31%), Positives = 87/171 (50%), Gaps = 17/171 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN----- 204
L+ L+L G +L ++I LK+L LD+S N +E+LP E + +L++L ++ N
Sbjct: 199 LKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETI 258
Query: 205 --------QLGVRGVVDWRWLLGPQIT---KTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
+L + V R P+ ++L L LT N+L LPK+I KL+KL L
Sbjct: 259 PDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLN 318
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
A+ N + LP IG +L F + N L +P + Q L +D++ N+
Sbjct: 319 ADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNR 369
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L++L + N + +LP G +L+EL L NQL L I K KL
Sbjct: 265 LKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQL---------LTLPKSIGKLKKLS 315
Query: 230 DLTS--NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+L + NKL LPK I L DN ++R+PA + + + L ++ N L LP
Sbjct: 316 NLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL 375
Query: 288 SLMQCRLEYIDISSNKFDNKQNNSTSDQYS 317
SL +L+ + +S N+ T Y+
Sbjct: 376 SLTALKLKALWLSDNQSQPLLTFQTDTDYT 405
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 18/180 (10%)
Query: 133 LVISDRSQFPAKGLPRT------LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKL 186
L ++D S P LP + L L ++ + L + +I L +LA L+L N + L
Sbjct: 107 LQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYL 166
Query: 187 PPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIW 244
P ++ L EL L NN++ + L I L L DL N+L LP+ I
Sbjct: 167 PDSLTQLRRLEELDLGNNEI---------YNLPESIGALLHLKDLWLDGNQLSELPQEIG 217
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
L+ L+ L ++N + RLP I +++L IS N L+++P + + +L + + N+
Sbjct: 218 NLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNR 277
>AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 8/160 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/171 (31%), Positives = 87/171 (50%), Gaps = 17/171 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN----- 204
L+ L+L G +L ++I LK+L LD+S N +E+LP E + +L++L ++ N
Sbjct: 199 LKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETI 258
Query: 205 --------QLGVRGVVDWRWLLGPQIT---KTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
+L + V R P+ ++L L LT N+L LPK+I KL+KL L
Sbjct: 259 PDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLN 318
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
A+ N + LP IG +L F + N L +P + Q L +D++ N+
Sbjct: 319 ADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNR 369
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L++L + N + +LP G +L+EL L NQL L I K KL
Sbjct: 265 LKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQL---------LTLPKSIGKLKKLS 315
Query: 230 DLTS--NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+L + NKL LPK I L DN ++R+PA + + + L ++ N L LP
Sbjct: 316 NLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL 375
Query: 288 SLMQCRLEYIDISSNKFDNKQNNSTSDQYS 317
SL +L+ + +S N+ T Y+
Sbjct: 376 SLTALKLKALWLSDNQSQPLLTFQTDTDYT 405
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 18/180 (10%)
Query: 133 LVISDRSQFPAKGLPRT------LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKL 186
L ++D S P LP + L L ++ + L + +I L +LA L+L N + L
Sbjct: 107 LQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYL 166
Query: 187 PPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIW 244
P ++ L EL L NN++ + L I L L DL N+L LP+ I
Sbjct: 167 PDSLTQLRRLEELDLGNNEI---------YNLPESIGALLHLKDLWLDGNQLSELPQEIG 217
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
L+ L+ L ++N + RLP I +++L IS N L+++P + + +L + + N+
Sbjct: 218 NLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNR 277
>AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens
cDNA FLJ11834 fis, clone HEMBA1006583, weakly similar to
Drosophila melanogaster Scribble (scrib) mRNA. ).
Length = 197
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 8/160 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
>AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein
protein.
Length = 524
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 8/160 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/171 (31%), Positives = 87/171 (50%), Gaps = 17/171 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN----- 204
L+ L+L G +L ++I LK+L LD+S N +E+LP E + +L++L ++ N
Sbjct: 199 LKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETI 258
Query: 205 --------QLGVRGVVDWRWLLGPQIT---KTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
+L + V R P+ ++L L LT N+L LPK+I KL+KL L
Sbjct: 259 PDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLN 318
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
A+ N + LP IG +L F + N L +P + Q L +D++ N+
Sbjct: 319 ADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNR 369
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L++L + N + +LP G +L+EL L NQL L I K KL
Sbjct: 265 LKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQL---------LTLPKSIGKLKKLS 315
Query: 230 DLTS--NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+L + NKL LPK I L DN ++R+PA + + + L ++ N L LP
Sbjct: 316 NLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL 375
Query: 288 SLMQCRLEYIDISSNKFDNKQNNSTSDQYS 317
SL +L+ + +S N+ T Y+
Sbjct: 376 SLTALKLKALWLSDNQSQPLLTFQTDTDYT 405
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 18/180 (10%)
Query: 133 LVISDRSQFPAKGLPRT------LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKL 186
L ++D S P LP + L L ++ + L + +I L +LA L+L N + L
Sbjct: 107 LQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYL 166
Query: 187 PPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIW 244
P ++ L EL L NN++ + L I L L DL N+L LP+ I
Sbjct: 167 PDSLTQLRRLEELDLGNNEI---------YNLPESIGALLHLKDLWLDGNQLSELPQEIG 217
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
L+ L+ L ++N + RLP I +++L IS N L+++P + + +L + + N+
Sbjct: 218 NLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNR 277
>AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats
protein protein.
Length = 524
Score = 75.4 bits (177), Expect = 3e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 8/160 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/171 (31%), Positives = 87/171 (50%), Gaps = 17/171 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN----- 204
L+ L+L G +L ++I LK+L LD+S N +E+LP E + +L++L ++ N
Sbjct: 199 LKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETI 258
Query: 205 --------QLGVRGVVDWRWLLGPQIT---KTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
+L + V R P+ ++L L LT N+L LPK+I KL+KL L
Sbjct: 259 PDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLN 318
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
A+ N + LP IG +L F + N L +P + Q L +D++ N+
Sbjct: 319 ADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNR 369
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L++L + N + +LP G +L+EL L NQL L I K KL
Sbjct: 265 LKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQL---------LTLPKSIGKLKKLS 315
Query: 230 DLTS--NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+L + NKL LPK I L DN ++R+PA + + + L ++ N L LP
Sbjct: 316 NLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL 375
Query: 288 SLMQCRLEYIDISSNKFDNKQNNSTSDQYS 317
SL +L+ + +S N+ T Y+
Sbjct: 376 SLTALKLKALWLSDNQSQPLLTFQTDTDYT 405
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 18/180 (10%)
Query: 133 LVISDRSQFPAKGLPRT------LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKL 186
L ++D S P LP + L L ++ + L + +I L +LA L+L N + L
Sbjct: 107 LQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYL 166
Query: 187 PPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIW 244
P ++ L EL L NN++ + L I L L DL N+L LP+ I
Sbjct: 167 PDSLTQLRRLEELDLGNNEI---------YNLPESIGALLHLKDLWLDGNQLSELPQEIG 217
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
L+ L+ L ++N + RLP I +++L IS N L+++P + + +L + + N+
Sbjct: 218 NLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNR 277
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/156 (32%), Positives = 87/156 (55%), Gaps = 12/156 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L +S KL + D+ LL L VLD+ +N++ LP + NL +L++++N+L +
Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI- 142
Query: 210 GVVDWRWLLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L +IT + LK L L N+L + + +L L L ++N ++ +PA+
Sbjct: 143 --------LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFS 194
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
+S+L +SSNEL+SLP + + RL+++D +SN
Sbjct: 195 SLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSN 230
Score = 58.0 bits (134), Expect = 6e-08
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
LQ L +S KL +I L++L L L +NE+ + F +++NL +L L+NN L
Sbjct: 130 LQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTV 189
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
+L L+L+SN+L LP I ++++L L N N++ +P + +
Sbjct: 190 PA-------SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGM 242
Query: 270 STLRYFTISSNELQSLP----CSLMQ 291
+L + N+L+ LP CSL++
Sbjct: 243 ESLELLYLRRNKLRFLPEFPSCSLLK 268
Score = 57.6 bits (133), Expect = 7e-08
Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 9/155 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L L LS +L + +I +K L LD ++N +E +PPE M +L L+L N+L
Sbjct: 198 SLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL-- 255
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIG 267
R+L LK L + N++ L K L ++ L DN + +P I
Sbjct: 256 ------RFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII 309
Query: 268 RISTLRYFTISSNELQSLPCSLMQCRLEYIDISSN 302
+ +L +S+N++ SLP SL L+++ + N
Sbjct: 310 LLRSLERLDLSNNDISSLPYSLGNLHLKFLALEGN 344
Score = 50.4 bits (115), Expect = 1e-05
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 19/173 (10%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL- 206
R L+ LYL +L L +L LDLSNN + +P F +++L L+L++N+L
Sbjct: 151 RNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELK 210
Query: 207 ----GVRGVVDWRWL---------LGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ + + L + P++ ++L+LL L NKL LP+ L
Sbjct: 211 SLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKE 269
Query: 252 LKANDNMISRLPAT-IGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L +N I L A + ++++ + N+L+S+P ++ R LE +D+S+N
Sbjct: 270 LHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNN 322
Score = 48.4 bits (110), Expect = 5e-05
Identities = 35/136 (25%), Positives = 66/136 (48%), Gaps = 8/136 (5%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 205
L + + LS KL ++ +L+ L LDL NN + LP E + L ++L+ N+
Sbjct: 447 LKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNR 506
Query: 206 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPA 264
+ V +R TL+ + +++N++G + P+ + +E L TL +N + ++P
Sbjct: 507 FKMLPEVLYRIF-------TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPP 559
Query: 265 TIGRISTLRYFTISSN 280
+G LR + N
Sbjct: 560 ELGNCVNLRTLLLDGN 575
Score = 42.3 bits (95), Expect = 0.003
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 222 ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNE 281
+ + L LDL +N L LP+ + L +L T+ + N LP + RI TL IS+N+
Sbjct: 470 VLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 529
Query: 282 LQSLPCSLMQC--RLEYIDISSN 302
+ S+ M+ L +D+ +N
Sbjct: 530 VGSVDPQKMKMMENLTTLDLQNN 552
Score = 37.9 bits (84), Expect = 0.064
Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 173 LAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +LD S+ + +P E F + + ++ ++ + NQL + R + ++ + + +
Sbjct: 401 LKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCE---IPKRMV---ELKEMVSDV 454
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL+ NKL + + L+KL L +N ++ LP + + L+ +S N + LP L
Sbjct: 455 DLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL 514
Query: 290 MQC-RLEYIDISSNK 303
+ LE I IS+N+
Sbjct: 515 YRIFTLETILISNNQ 529
Score = 37.5 bits (83), Expect = 0.085
Identities = 36/158 (22%), Positives = 74/158 (46%), Gaps = 14/158 (8%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAV-LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRG 210
S+ S +LC + ++ LK + +DLS N++ + E + L+ L L NN L
Sbjct: 429 SINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLN--- 485
Query: 211 VVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIG 267
L ++ ++L ++L+ N+ LP+ ++++ L T+ ++N + + P +
Sbjct: 486 ------SLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMK 539
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKF 304
+ L + +N+L +P L C L + + N F
Sbjct: 540 MMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPF 577
Score = 37.5 bits (83), Expect = 0.085
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 149 TLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
TL+++ +S ++ + + + ++++L LDL NN++ ++PPE G NL L L N
Sbjct: 519 TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFR 578
Query: 208 V 208
V
Sbjct: 579 V 579
Score = 33.5 bits (73), Expect = 1.4
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L+L+ L +P+ +W++ + +AN N+ + L IS+N+LQSL
Sbjct: 41 LNLSGRNLSEVPQCVWRINVDIPEEANQNLSFGATERWWEQTDLTKLIISNNKLQSLTDD 100
Query: 289 L-MQCRLEYIDISSNK 303
L + L +DI N+
Sbjct: 101 LRLLPALTVLDIHDNQ 116
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/156 (32%), Positives = 87/156 (55%), Gaps = 12/156 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L +S KL + D+ LL L VLD+ +N++ LP + NL +L++++N+L +
Sbjct: 63 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI- 121
Query: 210 GVVDWRWLLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L +IT + LK L L N+L + + +L L L ++N ++ +PA+
Sbjct: 122 --------LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFS 173
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
+S+L +SSNEL+SLP + + RL+++D +SN
Sbjct: 174 SLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSN 209
Score = 58.0 bits (134), Expect = 6e-08
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
LQ L +S KL +I L++L L L +NE+ + F +++NL +L L+NN L
Sbjct: 109 LQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTV 168
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
+L L+L+SN+L LP I ++++L L N N++ +P + +
Sbjct: 169 PA-------SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGM 221
Query: 270 STLRYFTISSNELQSLP----CSLMQ 291
+L + N+L+ LP CSL++
Sbjct: 222 ESLELLYLRRNKLRFLPEFPSCSLLK 247
Score = 57.6 bits (133), Expect = 7e-08
Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 9/155 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L L LS +L + +I +K L LD ++N +E +PPE M +L L+L N+L
Sbjct: 177 SLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL-- 234
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIG 267
R+L LK L + N++ L K L ++ L DN + +P I
Sbjct: 235 ------RFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII 288
Query: 268 RISTLRYFTISSNELQSLPCSLMQCRLEYIDISSN 302
+ +L +S+N++ SLP SL L+++ + N
Sbjct: 289 LLRSLERLDLSNNDISSLPYSLGNLHLKFLALEGN 323
Score = 50.4 bits (115), Expect = 1e-05
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 19/173 (10%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL- 206
R L+ LYL +L L +L LDLSNN + +P F +++L L+L++N+L
Sbjct: 130 RNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELK 189
Query: 207 ----GVRGVVDWRWL---------LGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ + + L + P++ ++L+LL L NKL LP+ L
Sbjct: 190 SLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKE 248
Query: 252 LKANDNMISRLPAT-IGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L +N I L A + ++++ + N+L+S+P ++ R LE +D+S+N
Sbjct: 249 LHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNN 301
Score = 48.4 bits (110), Expect = 5e-05
Identities = 35/136 (25%), Positives = 66/136 (48%), Gaps = 8/136 (5%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 205
L + + LS KL ++ +L+ L LDL NN + LP E + L ++L+ N+
Sbjct: 426 LKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNR 485
Query: 206 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPA 264
+ V +R TL+ + +++N++G + P+ + +E L TL +N + ++P
Sbjct: 486 FKMLPEVLYRIF-------TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPP 538
Query: 265 TIGRISTLRYFTISSN 280
+G LR + N
Sbjct: 539 ELGNCVNLRTLLLDGN 554
Score = 42.3 bits (95), Expect = 0.003
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 222 ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNE 281
+ + L LDL +N L LP+ + L +L T+ + N LP + RI TL IS+N+
Sbjct: 449 VLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 508
Query: 282 LQSLPCSLMQC--RLEYIDISSN 302
+ S+ M+ L +D+ +N
Sbjct: 509 VGSVDPQKMKMMENLTTLDLQNN 531
Score = 37.9 bits (84), Expect = 0.064
Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 173 LAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +LD S+ + +P E F + + ++ ++ + NQL + R + ++ + + +
Sbjct: 380 LKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCE---IPKRMV---ELKEMVSDV 433
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL+ NKL + + L+KL L +N ++ LP + + L+ +S N + LP L
Sbjct: 434 DLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL 493
Query: 290 MQC-RLEYIDISSNK 303
+ LE I IS+N+
Sbjct: 494 YRIFTLETILISNNQ 508
Score = 37.5 bits (83), Expect = 0.085
Identities = 36/158 (22%), Positives = 74/158 (46%), Gaps = 14/158 (8%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAV-LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRG 210
S+ S +LC + ++ LK + +DLS N++ + E + L+ L L NN L
Sbjct: 408 SINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLN--- 464
Query: 211 VVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIG 267
L ++ ++L ++L+ N+ LP+ ++++ L T+ ++N + + P +
Sbjct: 465 ------SLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMK 518
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKF 304
+ L + +N+L +P L C L + + N F
Sbjct: 519 MMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPF 556
Score = 37.5 bits (83), Expect = 0.085
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 149 TLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
TL+++ +S ++ + + + ++++L LDL NN++ ++PPE G NL L L N
Sbjct: 498 TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFR 557
Query: 208 V 208
V
Sbjct: 558 V 558
Score = 33.5 bits (73), Expect = 1.4
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L+L+ L +P+ +W++ + +AN N+ + L IS+N+LQSL
Sbjct: 20 LNLSGRNLSEVPQCVWRINVDIPEEANQNLSFGATERWWEQTDLTKLIISNNKLQSLTDD 79
Query: 289 L-MQCRLEYIDISSNK 303
L + L +DI N+
Sbjct: 80 LRLLPALTVLDIHDNQ 95
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/156 (32%), Positives = 87/156 (55%), Gaps = 12/156 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L +S KL + D+ LL L VLD+ +N++ LP + NL +L++++N+L +
Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI- 142
Query: 210 GVVDWRWLLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L +IT + LK L L N+L + + +L L L ++N ++ +PA+
Sbjct: 143 --------LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFS 194
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
+S+L +SSNEL+SLP + + RL+++D +SN
Sbjct: 195 SLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSN 230
Score = 58.0 bits (134), Expect = 6e-08
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
LQ L +S KL +I L++L L L +NE+ + F +++NL +L L+NN L
Sbjct: 130 LQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTV 189
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
+L L+L+SN+L LP I ++++L L N N++ +P + +
Sbjct: 190 PA-------SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGM 242
Query: 270 STLRYFTISSNELQSLP----CSLMQ 291
+L + N+L+ LP CSL++
Sbjct: 243 ESLELLYLRRNKLRFLPEFPSCSLLK 268
Score = 57.6 bits (133), Expect = 7e-08
Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 9/155 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L L LS +L + +I +K L LD ++N +E +PPE M +L L+L N+L
Sbjct: 198 SLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL-- 255
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIG 267
R+L LK L + N++ L K L ++ L DN + +P I
Sbjct: 256 ------RFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII 309
Query: 268 RISTLRYFTISSNELQSLPCSLMQCRLEYIDISSN 302
+ +L +S+N++ SLP SL L+++ + N
Sbjct: 310 LLRSLERLDLSNNDISSLPYSLGNLHLKFLALEGN 344
Score = 50.4 bits (115), Expect = 1e-05
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 19/173 (10%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL- 206
R L+ LYL +L L +L LDLSNN + +P F +++L L+L++N+L
Sbjct: 151 RNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELK 210
Query: 207 ----GVRGVVDWRWL---------LGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ + + L + P++ ++L+LL L NKL LP+ L
Sbjct: 211 SLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKE 269
Query: 252 LKANDNMISRLPAT-IGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L +N I L A + ++++ + N+L+S+P ++ R LE +D+S+N
Sbjct: 270 LHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNN 322
Score = 48.4 bits (110), Expect = 5e-05
Identities = 35/136 (25%), Positives = 66/136 (48%), Gaps = 8/136 (5%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 205
L + + LS KL ++ +L+ L LDL NN + LP E + L ++L+ N+
Sbjct: 447 LKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNR 506
Query: 206 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPA 264
+ V +R TL+ + +++N++G + P+ + +E L TL +N + ++P
Sbjct: 507 FKMLPEVLYRIF-------TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPP 559
Query: 265 TIGRISTLRYFTISSN 280
+G LR + N
Sbjct: 560 ELGNCVNLRTLLLDGN 575
Score = 42.3 bits (95), Expect = 0.003
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 222 ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNE 281
+ + L LDL +N L LP+ + L +L T+ + N LP + RI TL IS+N+
Sbjct: 470 VLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 529
Query: 282 LQSLPCSLMQC--RLEYIDISSN 302
+ S+ M+ L +D+ +N
Sbjct: 530 VGSVDPQKMKMMENLTTLDLQNN 552
Score = 37.9 bits (84), Expect = 0.064
Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 173 LAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +LD S+ + +P E F + + ++ ++ + NQL + R + ++ + + +
Sbjct: 401 LKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCE---IPKRMV---ELKEMVSDV 454
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL+ NKL + + L+KL L +N ++ LP + + L+ +S N + LP L
Sbjct: 455 DLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL 514
Query: 290 MQC-RLEYIDISSNK 303
+ LE I IS+N+
Sbjct: 515 YRIFTLETILISNNQ 529
Score = 37.5 bits (83), Expect = 0.085
Identities = 36/158 (22%), Positives = 74/158 (46%), Gaps = 14/158 (8%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAV-LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRG 210
S+ S +LC + ++ LK + +DLS N++ + E + L+ L L NN L
Sbjct: 429 SINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLN--- 485
Query: 211 VVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIG 267
L ++ ++L ++L+ N+ LP+ ++++ L T+ ++N + + P +
Sbjct: 486 ------SLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMK 539
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKF 304
+ L + +N+L +P L C L + + N F
Sbjct: 540 MMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPF 577
Score = 37.5 bits (83), Expect = 0.085
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 149 TLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
TL+++ +S ++ + + + ++++L LDL NN++ ++PPE G NL L L N
Sbjct: 519 TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFR 578
Query: 208 V 208
V
Sbjct: 579 V 579
Score = 33.5 bits (73), Expect = 1.4
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L+L+ L +P+ +W++ + +AN N+ + L IS+N+LQSL
Sbjct: 41 LNLSGRNLSEVPQCVWRINVDIPEEANQNLSFGATERWWEQTDLTKLIISNNKLQSLTDD 100
Query: 289 L-MQCRLEYIDISSNK 303
L + L +DI N+
Sbjct: 101 LRLLPALTVLDIHDNQ 116
>AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens
cDNA FLJ12889 fis, clone NT2RP2004098, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 602
Score = 74.9 bits (176), Expect = 5e-13
Identities = 50/156 (32%), Positives = 87/156 (55%), Gaps = 12/156 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L +S KL + D+ LL L VLD+ +N++ LP + NL +L++++N+L +
Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI- 142
Query: 210 GVVDWRWLLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L +IT + LK L L N+L + + +L L L ++N ++ +PA+
Sbjct: 143 --------LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFS 194
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
+S+L +SSNEL+SLP + + RL+++D +SN
Sbjct: 195 SLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSN 230
Score = 58.0 bits (134), Expect = 6e-08
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
LQ L +S KL +I L++L L L +NE+ + F +++NL +L L+NN L
Sbjct: 130 LQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTV 189
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
+L L+L+SN+L LP I ++++L L N N++ +P + +
Sbjct: 190 PA-------SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGM 242
Query: 270 STLRYFTISSNELQSLP----CSLMQ 291
+L + N+L+ LP CSL++
Sbjct: 243 ESLELLYLRRNKLRFLPEFPSCSLLK 268
Score = 57.6 bits (133), Expect = 7e-08
Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 9/155 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L L LS +L + +I +K L LD ++N +E +PPE M +L L+L N+L
Sbjct: 198 SLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL-- 255
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIG 267
R+L LK L + N++ L K L ++ L DN + +P I
Sbjct: 256 ------RFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII 309
Query: 268 RISTLRYFTISSNELQSLPCSLMQCRLEYIDISSN 302
+ +L +S+N++ SLP SL L+++ + N
Sbjct: 310 LLRSLERLDLSNNDISSLPYSLGNLHLKFLALEGN 344
Score = 50.4 bits (115), Expect = 1e-05
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 19/173 (10%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL- 206
R L+ LYL +L L +L LDLSNN + +P F +++L L+L++N+L
Sbjct: 151 RNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELK 210
Query: 207 ----GVRGVVDWRWL---------LGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ + + L + P++ ++L+LL L NKL LP+ L
Sbjct: 211 SLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKE 269
Query: 252 LKANDNMISRLPAT-IGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L +N I L A + ++++ + N+L+S+P ++ R LE +D+S+N
Sbjct: 270 LHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNN 322
Score = 48.4 bits (110), Expect = 5e-05
Identities = 35/136 (25%), Positives = 66/136 (48%), Gaps = 8/136 (5%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 205
L + + LS KL ++ +L+ L LDL NN + LP E + L ++L+ N+
Sbjct: 447 LKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNR 506
Query: 206 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPA 264
+ V +R TL+ + +++N++G + P+ + +E L TL +N + ++P
Sbjct: 507 FKMLPEVLYRIF-------TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPP 559
Query: 265 TIGRISTLRYFTISSN 280
+G LR + N
Sbjct: 560 ELGNCVNLRTLLLDGN 575
Score = 42.3 bits (95), Expect = 0.003
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 222 ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNE 281
+ + L LDL +N L LP+ + L +L T+ + N LP + RI TL IS+N+
Sbjct: 470 VLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 529
Query: 282 LQSLPCSLMQC--RLEYIDISSN 302
+ S+ M+ L +D+ +N
Sbjct: 530 VGSVDPQKMKMMENLTTLDLQNN 552
Score = 37.9 bits (84), Expect = 0.064
Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 173 LAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +LD S+ + +P E F + + ++ ++ + NQL + R + ++ + + +
Sbjct: 401 LKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCE---IPKRMV---ELKEMVSDV 454
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL+ NKL + + L+KL L +N ++ LP + + L+ +S N + LP L
Sbjct: 455 DLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL 514
Query: 290 MQC-RLEYIDISSNK 303
+ LE I IS+N+
Sbjct: 515 YRIFTLETILISNNQ 529
Score = 37.5 bits (83), Expect = 0.085
Identities = 36/158 (22%), Positives = 74/158 (46%), Gaps = 14/158 (8%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAV-LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRG 210
S+ S +LC + ++ LK + +DLS N++ + E + L+ L L NN L
Sbjct: 429 SINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLN--- 485
Query: 211 VVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIG 267
L ++ ++L ++L+ N+ LP+ ++++ L T+ ++N + + P +
Sbjct: 486 ------SLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMK 539
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKF 304
+ L + +N+L +P L C L + + N F
Sbjct: 540 MMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPF 577
Score = 37.5 bits (83), Expect = 0.085
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 149 TLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
TL+++ +S ++ + + + ++++L LDL NN++ ++PPE G NL L L N
Sbjct: 519 TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFR 578
Query: 208 V 208
V
Sbjct: 579 V 579
Score = 33.5 bits (73), Expect = 1.4
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L+L+ L +P+ +W++ + +AN N+ + L IS+N+LQSL
Sbjct: 41 LNLSGRNLSEVPQCVWRINVDIPEEANQNLSFGATERWWEQTDLTKLIISNNKLQSLTDD 100
Query: 289 L-MQCRLEYIDISSNK 303
L + L +DI N+
Sbjct: 101 LRLLPALTVLDIHDNQ 116
>D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein.
Length = 1630
Score = 74.1 bits (174), Expect = 8e-13
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ L L +L + L +L L LS+NEI++LPPE L EL ++ N
Sbjct: 36 RSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRND-- 93
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + + K L++ D + N L LP +L L L ND + LP +G
Sbjct: 94 IPEIPE-----SIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVG 148
Query: 268 RISTLRYFTISSNELQSLPCSL-MQCRLEYIDISSNKFD 305
++ L + N L+SLP SL +LE +D+ N +
Sbjct: 149 NLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLE 187
Score = 60.1 bits (139), Expect = 1e-08
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 14/178 (7%)
Query: 133 LVISDRSQFPAKGLP------RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKL 186
L I+D S P LP R+L L L+ + L D+ L +L L+L N ++ L
Sbjct: 107 LEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSL 166
Query: 187 PPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKL 246
P + L +L L N L V + D LG L+ L L N+L LP + L
Sbjct: 167 PASLSFLVKLEQLDLGGNDLEV--LPD---TLGA--LPNLRELWLDRNQLSALPPELGNL 219
Query: 247 EKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+LV L ++N + LPA +G + L +S N L+ LP + Q + L + + N+
Sbjct: 220 RRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNR 277
Score = 58.0 bits (134), Expect = 6e-08
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 17/174 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
L+ L+L +L ++ L+ L LD+S N +E+LP E G + L++L L+ N L
Sbjct: 199 LRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRL 258
Query: 207 --GVRGVVDWRWLLGPQ-----ITKT------LKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G+ + L Q +T+ L L LT N L LP+++ KL KL L
Sbjct: 259 PDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLN 318
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKFDN 306
+ N + LP IG L ++ N L LP L L +D++ N+ +
Sbjct: 319 VDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQS 372
Score = 52.4 bits (120), Expect = 3e-06
Identities = 49/165 (29%), Positives = 72/165 (43%), Gaps = 7/165 (4%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L LS L I LK L++L + N + ++ G NLSEL L N L
Sbjct: 245 LTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLL--- 301
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
+ LG ++TK L L++ N L LP I L L DN ++ LP +
Sbjct: 302 --MALPRSLG-KLTK-LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 357
Query: 270 STLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTSD 314
+ L ++ N LQSLP +L L+ + ++ N+ T D
Sbjct: 358 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPMLRFQTED 402
Score = 49.2 bits (112), Expect = 3e-05
Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
+++L+ L L +N+L LPK ++L L L +DN I RLP + L +S N++
Sbjct: 35 SRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDI 94
Query: 283 QSLPCSLMQCR-LEYIDISSN 302
+P S+ C+ LE D S N
Sbjct: 95 PEIPESIKFCKALEIADFSGN 115
>AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein.
Length = 1630
Score = 74.1 bits (174), Expect = 8e-13
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ L L +L + L +L L LS+NEI++LPPE L EL ++ N
Sbjct: 36 RSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRND-- 93
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + + K L++ D + N L LP +L L L ND + LP +G
Sbjct: 94 IPEIPE-----SIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVG 148
Query: 268 RISTLRYFTISSNELQSLPCSL-MQCRLEYIDISSNKFD 305
++ L + N L+SLP SL +LE +D+ N +
Sbjct: 149 NLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLE 187
Score = 60.1 bits (139), Expect = 1e-08
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 14/178 (7%)
Query: 133 LVISDRSQFPAKGLP------RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKL 186
L I+D S P LP R+L L L+ + L D+ L +L L+L N ++ L
Sbjct: 107 LEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSL 166
Query: 187 PPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKL 246
P + L +L L N L V + D LG L+ L L N+L LP + L
Sbjct: 167 PASLSFLVKLEQLDLGGNDLEV--LPD---TLGA--LPNLRELWLDRNQLSALPPELGNL 219
Query: 247 EKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+LV L ++N + LPA +G + L +S N L+ LP + Q + L + + N+
Sbjct: 220 RRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNR 277
Score = 58.0 bits (134), Expect = 6e-08
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 17/174 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
L+ L+L +L ++ L+ L LD+S N +E+LP E G + L++L L+ N L
Sbjct: 199 LRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRL 258
Query: 207 --GVRGVVDWRWLLGPQ-----ITKT------LKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G+ + L Q +T+ L L LT N L LP+++ KL KL L
Sbjct: 259 PDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLN 318
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKFDN 306
+ N + LP IG L ++ N L LP L L +D++ N+ +
Sbjct: 319 VDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQS 372
Score = 52.4 bits (120), Expect = 3e-06
Identities = 49/165 (29%), Positives = 72/165 (43%), Gaps = 7/165 (4%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L LS L I LK L++L + N + ++ G NLSEL L N L
Sbjct: 245 LTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLL--- 301
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
+ LG ++TK L L++ N L LP I L L DN ++ LP +
Sbjct: 302 --MALPRSLG-KLTK-LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 357
Query: 270 STLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTSD 314
+ L ++ N LQSLP +L L+ + ++ N+ T D
Sbjct: 358 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPMLRFQTED 402
Score = 49.2 bits (112), Expect = 3e-05
Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
+++L+ L L +N+L LPK ++L L L +DN I RLP + L +S N++
Sbjct: 35 SRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDI 94
Query: 283 QSLPCSLMQCR-LEYIDISSN 302
+P S+ C+ LE D S N
Sbjct: 95 PEIPESIKFCKALEIADFSGN 115
>AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein.
Length = 1630
Score = 74.1 bits (174), Expect = 8e-13
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ L L +L + L +L L LS+NEI++LPPE L EL ++ N
Sbjct: 36 RSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRND-- 93
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + + K L++ D + N L LP +L L L ND + LP +G
Sbjct: 94 IPEIPE-----SIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVG 148
Query: 268 RISTLRYFTISSNELQSLPCSL-MQCRLEYIDISSNKFD 305
++ L + N L+SLP SL +LE +D+ N +
Sbjct: 149 NLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLE 187
Score = 60.1 bits (139), Expect = 1e-08
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 14/178 (7%)
Query: 133 LVISDRSQFPAKGLP------RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKL 186
L I+D S P LP R+L L L+ + L D+ L +L L+L N ++ L
Sbjct: 107 LEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSL 166
Query: 187 PPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKL 246
P + L +L L N L V + D LG L+ L L N+L LP + L
Sbjct: 167 PASLSFLVKLEQLDLGGNDLEV--LPD---TLGA--LPNLRELWLDRNQLSALPPELGNL 219
Query: 247 EKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+LV L ++N + LPA +G + L +S N L+ LP + Q + L + + N+
Sbjct: 220 RRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNR 277
Score = 58.0 bits (134), Expect = 6e-08
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 17/174 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
L+ L+L +L ++ L+ L LD+S N +E+LP E G + L++L L+ N L
Sbjct: 199 LRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRL 258
Query: 207 --GVRGVVDWRWLLGPQ-----ITKT------LKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G+ + L Q +T+ L L LT N L LP+++ KL KL L
Sbjct: 259 PDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLN 318
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKFDN 306
+ N + LP IG L ++ N L LP L L +D++ N+ +
Sbjct: 319 VDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQS 372
Score = 52.4 bits (120), Expect = 3e-06
Identities = 49/165 (29%), Positives = 72/165 (43%), Gaps = 7/165 (4%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L LS L I LK L++L + N + ++ G NLSEL L N L
Sbjct: 245 LTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLL--- 301
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
+ LG ++TK L L++ N L LP I L L DN ++ LP +
Sbjct: 302 --MALPRSLG-KLTK-LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 357
Query: 270 STLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTSD 314
+ L ++ N LQSLP +L L+ + ++ N+ T D
Sbjct: 358 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPMLRFQTED 402
Score = 49.2 bits (112), Expect = 3e-05
Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
+++L+ L L +N+L LPK ++L L L +DN I RLP + L +S N++
Sbjct: 35 SRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDI 94
Query: 283 QSLPCSLMQCR-LEYIDISSN 302
+P S+ C+ LE D S N
Sbjct: 95 PEIPESIKFCKALEIADFSGN 115
>AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 72.1 bits (169), Expect = 3e-12
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N G
Sbjct: 51 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--G 108
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V+ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 109 VQEFPE-----NIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 163
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 164 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 225
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 188 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 247
Query: 226 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 248 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 307
Query: 274 YFTISSNELQSLPCSL 289
F S NEL+SLP ++
Sbjct: 308 EFDCSCNELESLPSTI 323
Score = 68.1 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 99 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 158
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R + L++L+L N L LPK++ KL +L L +N LP + +I
Sbjct: 159 PANFGRLV-------KLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQI 211
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
LR + +N LQ LP S+ + + L Y+D+S N+ +
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIE 248
Score = 57.6 bits (133), Expect = 7e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 270
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 271 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 324
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 325 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
DI + L L LS+N +++LP G + L+ L + +NQL + P
Sbjct: 253 DISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML----------PNTIGN 302
Query: 226 LKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L LL D + N+L LP I L L TL ++N + LP IG + ++ SN+L
Sbjct: 303 LSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKL 362
Query: 283 QSLPCSLMQC-RLEYIDISSNKFDN 306
+ LP + Q +L +++S N+ N
Sbjct: 363 EFLPEEIGQMQKLRVLNLSDNRLKN 387
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GV 208
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L +
Sbjct: 260 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 319
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ + +L+ L + N L LP+ I + + + N + LP IG+
Sbjct: 320 PSTIGY--------LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQ 371
Query: 269 ISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+ LR +S N L++LP S + + L + +S N+
Sbjct: 372 MQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 407
>AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 72.1 bits (169), Expect = 3e-12
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N G
Sbjct: 46 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--G 103
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V+ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 104 VQEFPE-----NIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 159 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 225
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 183 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 242
Query: 226 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 243 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 302
Query: 274 YFTISSNELQSLPCSL 289
F S NEL+SLP ++
Sbjct: 303 EFDCSCNELESLPSTI 318
Score = 68.1 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 94 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 153
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R + L++L+L N L LPK++ KL +L L +N LP + +I
Sbjct: 154 PANFGRLV-------KLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQI 206
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
LR + +N LQ LP S+ + + L Y+D+S N+ +
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIE 243
Score = 57.6 bits (133), Expect = 7e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 265
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 266 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 319
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 320 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
DI + L L LS+N +++LP G + L+ L + +NQL + P
Sbjct: 248 DISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML----------PNTIGN 297
Query: 226 LKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L LL D + N+L LP I L L TL ++N + LP IG + ++ SN+L
Sbjct: 298 LSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKL 357
Query: 283 QSLPCSLMQC-RLEYIDISSNKFDN 306
+ LP + Q +L +++S N+ N
Sbjct: 358 EFLPEEIGQMQKLRVLNLSDNRLKN 382
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GV 208
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L +
Sbjct: 255 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 314
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ + +L+ L + N L LP+ I + + + N + LP IG+
Sbjct: 315 PSTIGY--------LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQ 366
Query: 269 ISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+ LR +S N L++LP S + + L + +S N+
Sbjct: 367 MQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 402
>AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 72.1 bits (169), Expect = 3e-12
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N G
Sbjct: 51 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--G 108
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V+ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 109 VQEFPE-----NIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 163
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 164 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 225
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 188 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 247
Query: 226 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 248 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 307
Query: 274 YFTISSNELQSLPCSL 289
F S NEL+SLP ++
Sbjct: 308 EFDCSCNELESLPSTI 323
Score = 68.1 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 99 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 158
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R + L++L+L N L LPK++ KL +L L +N LP + +I
Sbjct: 159 PANFGRLV-------KLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQI 211
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
LR + +N LQ LP S+ + + L Y+D+S N+ +
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIE 248
Score = 57.6 bits (133), Expect = 7e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 270
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 271 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 324
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 325 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
DI + L L LS+N +++LP G + L+ L + +NQL + P
Sbjct: 253 DISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML----------PNTIGN 302
Query: 226 LKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L LL D + N+L LP I L L TL ++N + LP IG + ++ SN+L
Sbjct: 303 LSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKL 362
Query: 283 QSLPCSLMQC-RLEYIDISSNKFDN 306
+ LP + Q +L +++S N+ N
Sbjct: 363 EFLPEEIGQMQKLRVLNLSDNRLKN 387
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GV 208
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L +
Sbjct: 260 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 319
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ + +L+ L + N L LP+ I + + + N + LP IG+
Sbjct: 320 PSTIGY--------LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQ 371
Query: 269 ISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+ LR +S N L++LP S + + L + +S N+
Sbjct: 372 MQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 407
>AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 72.1 bits (169), Expect = 3e-12
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N G
Sbjct: 46 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--G 103
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V+ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 104 VQEFPE-----NIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 159 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 225
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 183 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 242
Query: 226 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 243 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 302
Query: 274 YFTISSNELQSLPCSL 289
F S NEL+SLP ++
Sbjct: 303 EFDCSCNELESLPSTI 318
Score = 68.1 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 94 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 153
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R + L++L+L N L LPK++ KL +L L +N LP + +I
Sbjct: 154 PANFGRLV-------KLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQI 206
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
LR + +N LQ LP S+ + + L Y+D+S N+ +
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIE 243
Score = 57.6 bits (133), Expect = 7e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 265
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 266 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 319
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 320 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
DI + L L LS+N +++LP G + L+ L + +NQL + P
Sbjct: 248 DISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML----------PNTIGN 297
Query: 226 LKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L LL D + N+L LP I L L TL ++N + LP IG + ++ SN+L
Sbjct: 298 LSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKL 357
Query: 283 QSLPCSLMQC-RLEYIDISSNKFDN 306
+ LP + Q +L +++S N+ N
Sbjct: 358 EFLPEEIGQMQKLRVLNLSDNRLKN 382
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GV 208
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L +
Sbjct: 255 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 314
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ + +L+ L + N L LP+ I + + + N + LP IG+
Sbjct: 315 PSTIGY--------LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQ 366
Query: 269 ISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+ LR +S N L++LP S + + L + +S N+
Sbjct: 367 MQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 402
>AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 72.1 bits (169), Expect = 3e-12
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N G
Sbjct: 51 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--G 108
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V+ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 109 VQEFPE-----NIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 163
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 164 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 225
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 188 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 247
Query: 226 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 248 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 307
Query: 274 YFTISSNELQSLPCSL 289
F S NEL+SLP ++
Sbjct: 308 EFDCSCNELESLPSTI 323
Score = 68.1 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 99 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 158
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R + L++L+L N L LPK++ KL +L L +N LP + +I
Sbjct: 159 PANFGRLV-------KLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQI 211
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
LR + +N LQ LP S+ + + L Y+D+S N+ +
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIE 248
Score = 57.6 bits (133), Expect = 7e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 270
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 271 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 324
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 325 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
DI + L L LS+N +++LP G + L+ L + +NQL + P
Sbjct: 253 DISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML----------PNTIGN 302
Query: 226 LKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L LL D + N+L LP I L L TL ++N + LP IG + ++ SN+L
Sbjct: 303 LSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKL 362
Query: 283 QSLPCSLMQC-RLEYIDISSNKFDN 306
+ LP + Q +L +++S N+ N
Sbjct: 363 EFLPEEIGQMQKLRVLNLSDNRLKN 387
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GV 208
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L +
Sbjct: 260 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 319
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ + +L+ L + N L LP+ I + + + N + LP IG+
Sbjct: 320 PSTIGY--------LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQ 371
Query: 269 ISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+ LR +S N L++LP S + + L + +S N+
Sbjct: 372 MQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 407
>AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 72.1 bits (169), Expect = 3e-12
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N G
Sbjct: 46 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--G 103
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V+ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 104 VQEFPE-----NIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 159 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 225
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 183 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 242
Query: 226 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 243 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 302
Query: 274 YFTISSNELQSLPCSL 289
F S NEL+SLP ++
Sbjct: 303 EFDCSCNELESLPSTI 318
Score = 68.1 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 94 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 153
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R + L++L+L N L LPK++ KL +L L +N LP + +I
Sbjct: 154 PANFGRLV-------KLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQI 206
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
LR + +N LQ LP S+ + + L Y+D+S N+ +
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIE 243
Score = 57.6 bits (133), Expect = 7e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 265
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 266 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 319
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 320 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
DI + L L LS+N +++LP G + L+ L + +NQL + P
Sbjct: 248 DISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML----------PNTIGN 297
Query: 226 LKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L LL D + N+L LP I L L TL ++N + LP IG + ++ SN+L
Sbjct: 298 LSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKL 357
Query: 283 QSLPCSLMQC-RLEYIDISSNKFDN 306
+ LP + Q +L +++S N+ N
Sbjct: 358 EFLPEEIGQMQKLRVLNLSDNRLKN 382
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GV 208
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L +
Sbjct: 255 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 314
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ + +L+ L + N L LP+ I + + + N + LP IG+
Sbjct: 315 PSTIGY--------LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQ 366
Query: 269 ISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+ LR +S N L++LP S + + L + +S N+
Sbjct: 367 MQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 402
>AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 72.1 bits (169), Expect = 3e-12
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N G
Sbjct: 51 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--G 108
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V+ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 109 VQEFPE-----NIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 163
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 164 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 225
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 188 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 247
Query: 226 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 248 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 307
Query: 274 YFTISSNELQSLPCSL 289
F S NEL+SLP ++
Sbjct: 308 EFDCSCNELESLPSTI 323
Score = 68.1 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 99 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 158
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R + L++L+L N L LPK++ KL +L L +N LP + +I
Sbjct: 159 PANFGRLV-------KLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQI 211
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
LR + +N LQ LP S+ + + L Y+D+S N+ +
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIE 248
Score = 57.6 bits (133), Expect = 7e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 270
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 271 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 324
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 325 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
DI + L L LS+N +++LP G + L+ L + +NQL + P
Sbjct: 253 DISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML----------PNTIGN 302
Query: 226 LKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L LL D + N+L LP I L L TL ++N + LP IG + ++ SN+L
Sbjct: 303 LSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKL 362
Query: 283 QSLPCSLMQC-RLEYIDISSNKFDN 306
+ LP + Q +L +++S N+ N
Sbjct: 363 EFLPEEIGQMQKLRVLNLSDNRLKN 387
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GV 208
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L +
Sbjct: 260 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 319
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ + +L+ L + N L LP+ I + + + N + LP IG+
Sbjct: 320 PSTIGY--------LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQ 371
Query: 269 ISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+ LR +S N L++LP S + + L + +S N+
Sbjct: 372 MQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 407
>AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 72.1 bits (169), Expect = 3e-12
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N G
Sbjct: 46 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--G 103
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V+ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 104 VQEFPE-----NIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 159 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 225
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 183 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 242
Query: 226 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 243 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 302
Query: 274 YFTISSNELQSLPCSL 289
F S NEL+SLP ++
Sbjct: 303 EFDCSCNELESLPSTI 318
Score = 68.1 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 94 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 153
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R + L++L+L N L LPK++ KL +L L +N LP + +I
Sbjct: 154 PANFGRLV-------KLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQI 206
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
LR + +N LQ LP S+ + + L Y+D+S N+ +
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIE 243
Score = 57.6 bits (133), Expect = 7e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 265
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 266 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 319
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 320 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
DI + L L LS+N +++LP G + L+ L + +NQL + P
Sbjct: 248 DISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML----------PNTIGN 297
Query: 226 LKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L LL D + N+L LP I L L TL ++N + LP IG + ++ SN+L
Sbjct: 298 LSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKL 357
Query: 283 QSLPCSLMQC-RLEYIDISSNKFDN 306
+ LP + Q +L +++S N+ N
Sbjct: 358 EFLPEEIGQMQKLRVLNLSDNRLKN 382
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GV 208
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L +
Sbjct: 255 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 314
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ + +L+ L + N L LP+ I + + + N + LP IG+
Sbjct: 315 PSTIGY--------LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQ 366
Query: 269 ISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+ LR +S N L++LP S + + L + +S N+
Sbjct: 367 MQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 402
>AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 72.1 bits (169), Expect = 3e-12
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N G
Sbjct: 51 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--G 108
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V+ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 109 VQEFPE-----NIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 163
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 164 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 225
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 188 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 247
Query: 226 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 248 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 307
Query: 274 YFTISSNELQSLPCSL 289
F S NEL+SLP ++
Sbjct: 308 EFDCSCNELESLPSTI 323
Score = 68.1 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 99 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 158
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R + L++L+L N L LPK++ KL +L L +N LP + +I
Sbjct: 159 PANFGRLV-------KLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQI 211
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
LR + +N LQ LP S+ + + L Y+D+S N+ +
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIE 248
Score = 57.6 bits (133), Expect = 7e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 270
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 271 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 324
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 325 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
DI + L L LS+N +++LP G + L+ L + +NQL + P
Sbjct: 253 DISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML----------PNTIGN 302
Query: 226 LKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L LL D + N+L LP I L L TL ++N + LP IG + ++ SN+L
Sbjct: 303 LSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKL 362
Query: 283 QSLPCSLMQC-RLEYIDISSNKFDN 306
+ LP + Q +L +++S N+ N
Sbjct: 363 EFLPEEIGQMQKLRVLNLSDNRLKN 387
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GV 208
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L +
Sbjct: 260 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 319
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ + +L+ L + N L LP+ I + + + N + LP IG+
Sbjct: 320 PSTIGY--------LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQ 371
Query: 269 ISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+ LR +S N L++LP S + + L + +S N+
Sbjct: 372 MQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 407
>AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein.
Length = 1537
Score = 72.1 bits (169), Expect = 3e-12
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N G
Sbjct: 46 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--G 103
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V+ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 104 VQEFPE-----NIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 159 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 72.1 bits (169), Expect = 3e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 225
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 183 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 242
Query: 226 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 243 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 302
Query: 274 YFTISSNELQSLPCSL 289
F S NEL+SLP ++
Sbjct: 303 EFDCSCNELESLPSTI 318
Score = 68.1 bits (159), Expect = 5e-11
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 94 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 153
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R + L++L+L N L LPK++ KL +L L +N LP + +I
Sbjct: 154 PANFGRLV-------KLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQI 206
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
LR + +N LQ LP S+ + + L Y+D+S N+ +
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIE 243
Score = 57.6 bits (133), Expect = 7e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 265
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 266 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 319
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 320 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Score = 56.8 bits (131), Expect = 1e-07
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
DI + L L LS+N +++LP G + L+ L + +NQL + P
Sbjct: 248 DISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML----------PNTIGN 297
Query: 226 LKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L LL D + N+L LP I L L TL ++N + LP IG + ++ SN+L
Sbjct: 298 LSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKL 357
Query: 283 QSLPCSLMQC-RLEYIDISSNKFDN 306
+ LP + Q +L +++S N+ N
Sbjct: 358 EFLPEEIGQMQKLRVLNLSDNRLKN 382
Score = 56.0 bits (129), Expect = 2e-07
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GV 208
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L +
Sbjct: 255 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 314
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ + +L+ L + N L LP+ I + + + N + LP IG+
Sbjct: 315 PSTIGY--------LHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQ 366
Query: 269 ISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+ LR +S N L++LP S + + L + +S N+
Sbjct: 367 MQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQ 402
>BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein.
Length = 239
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/164 (30%), Positives = 86/164 (52%), Gaps = 15/164 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+SL L+ KL +I LK L L L+NN + +LP FG+++ L L L+ NQLG
Sbjct: 64 LKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGA- 122
Query: 210 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L PQ+ + L ++DL+ N++ +P ++ +L+ ++ L N N IS++ I
Sbjct: 123 --------LPPQLCSLRHLDVMDLSKNQIRSIPDSVGELQ-VIELNLNQNQISQISVKIS 173
Query: 268 RISTLRYFTISSN--ELQSLPCSLM-QCRLEYIDISSNKFDNKQ 308
L+ + N EL LP S++ ++ + + N F+ K+
Sbjct: 174 CCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKK 217
Score = 67.3 bits (157), Expect = 9e-11
Identities = 45/131 (34%), Positives = 75/131 (57%), Gaps = 8/131 (6%)
Query: 175 VLDLSNNEIEKLPPEFGRM-ANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTS 233
V L + + + P + ++ +NL + L+NN++ + L+G + T LK L L +
Sbjct: 18 VFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPL----LIG-KFT-LLKSLSLNN 71
Query: 234 NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR 293
NKL LP I L+KL TL N+N + LP+T G++S L+ ++S N+L +LP L R
Sbjct: 72 NKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLR 131
Query: 294 -LEYIDISSNK 303
L+ +D+S N+
Sbjct: 132 HLDVMDLSKNQ 142
Score = 64.1 bits (149), Expect = 9e-10
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 13/148 (8%)
Query: 160 LCNFRRDIL-LLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWL 217
L F D+ L +L +DLSNN+IE LPP G+ L L L NN+L V
Sbjct: 26 LTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTV--------- 76
Query: 218 LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYF 275
L +I K L+ L L +N L LP +L L TL + N + LP + + L
Sbjct: 77 LPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVM 136
Query: 276 TISSNELQSLPCSLMQCRLEYIDISSNK 303
+S N+++S+P S+ + ++ ++++ N+
Sbjct: 137 DLSKNQIRSIPDSVGELQVIELNLNQNQ 164
Score = 33.1 bits (72), Expect = 1.8
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 10/135 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L++L L+ L L L L LS N++ LPP+ + +L + L+ NQ
Sbjct: 85 KKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQ-- 142
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM--ISRLPAT 265
+R + D L Q+ + L+L N++ + I +L L+ +N +S LP +
Sbjct: 143 IRSIPDSVGEL--QVIE----LNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQS 196
Query: 266 IGRISTLRYFTISSN 280
I S + + N
Sbjct: 197 ILSDSQICLLAVEGN 211
>AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens
cDNA FLJ37572 fis, clone BRCOC2002751, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 239
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/164 (30%), Positives = 86/164 (52%), Gaps = 15/164 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+SL L+ KL +I LK L L L+NN + +LP FG+++ L L L+ NQLG
Sbjct: 64 LKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGA- 122
Query: 210 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L PQ+ + L ++DL+ N++ +P ++ +L+ ++ L N N IS++ I
Sbjct: 123 --------LPPQLCSLRHLDVMDLSKNQIRSIPDSVGELQ-VIELNLNQNQISQISVKIS 173
Query: 268 RISTLRYFTISSN--ELQSLPCSLM-QCRLEYIDISSNKFDNKQ 308
L+ + N EL LP S++ ++ + + N F+ K+
Sbjct: 174 CCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKK 217
Score = 67.3 bits (157), Expect = 9e-11
Identities = 45/131 (34%), Positives = 75/131 (57%), Gaps = 8/131 (6%)
Query: 175 VLDLSNNEIEKLPPEFGRM-ANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTS 233
V L + + + P + ++ +NL + L+NN++ + L+G + T LK L L +
Sbjct: 18 VFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPL----LIG-KFT-LLKSLSLNN 71
Query: 234 NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR 293
NKL LP I L+KL TL N+N + LP+T G++S L+ ++S N+L +LP L R
Sbjct: 72 NKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLR 131
Query: 294 -LEYIDISSNK 303
L+ +D+S N+
Sbjct: 132 HLDVMDLSKNQ 142
Score = 64.1 bits (149), Expect = 9e-10
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 13/148 (8%)
Query: 160 LCNFRRDIL-LLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWL 217
L F D+ L +L +DLSNN+IE LPP G+ L L L NN+L V
Sbjct: 26 LTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTV--------- 76
Query: 218 LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYF 275
L +I K L+ L L +N L LP +L L TL + N + LP + + L
Sbjct: 77 LPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVM 136
Query: 276 TISSNELQSLPCSLMQCRLEYIDISSNK 303
+S N+++S+P S+ + ++ ++++ N+
Sbjct: 137 DLSKNQIRSIPDSVGELQVIELNLNQNQ 164
Score = 33.1 bits (72), Expect = 1.8
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 10/135 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L++L L+ L L L L LS N++ LPP+ + +L + L+ NQ
Sbjct: 85 KKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQ-- 142
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM--ISRLPAT 265
+R + D L Q+ + L+L N++ + I +L L+ +N +S LP +
Sbjct: 143 IRSIPDSVGEL--QVIE----LNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQS 196
Query: 266 IGRISTLRYFTISSN 280
I S + + N
Sbjct: 197 ILSDSQICLLAVEGN 211
>AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein.
Length = 239
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/164 (30%), Positives = 86/164 (52%), Gaps = 15/164 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+SL L+ KL +I LK L L L+NN + +LP FG+++ L L L+ NQLG
Sbjct: 64 LKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGA- 122
Query: 210 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L PQ+ + L ++DL+ N++ +P ++ +L+ ++ L N N IS++ I
Sbjct: 123 --------LPPQLCSLRHLDVMDLSKNQIRSIPDSVGELQ-VIELNLNQNQISQISVKIS 173
Query: 268 RISTLRYFTISSN--ELQSLPCSLM-QCRLEYIDISSNKFDNKQ 308
L+ + N EL LP S++ ++ + + N F+ K+
Sbjct: 174 CCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKK 217
Score = 67.3 bits (157), Expect = 9e-11
Identities = 45/131 (34%), Positives = 75/131 (57%), Gaps = 8/131 (6%)
Query: 175 VLDLSNNEIEKLPPEFGRM-ANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTS 233
V L + + + P + ++ +NL + L+NN++ + L+G + T LK L L +
Sbjct: 18 VFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPL----LIG-KFT-LLKSLSLNN 71
Query: 234 NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR 293
NKL LP I L+KL TL N+N + LP+T G++S L+ ++S N+L +LP L R
Sbjct: 72 NKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLR 131
Query: 294 -LEYIDISSNK 303
L+ +D+S N+
Sbjct: 132 HLDVMDLSKNQ 142
Score = 64.1 bits (149), Expect = 9e-10
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 13/148 (8%)
Query: 160 LCNFRRDIL-LLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWL 217
L F D+ L +L +DLSNN+IE LPP G+ L L L NN+L V
Sbjct: 26 LTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTV--------- 76
Query: 218 LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYF 275
L +I K L+ L L +N L LP +L L TL + N + LP + + L
Sbjct: 77 LPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVM 136
Query: 276 TISSNELQSLPCSLMQCRLEYIDISSNK 303
+S N+++S+P S+ + ++ ++++ N+
Sbjct: 137 DLSKNQIRSIPDSVGELQVIELNLNQNQ 164
Score = 33.1 bits (72), Expect = 1.8
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 10/135 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L++L L+ L L L L LS N++ LPP+ + +L + L+ NQ
Sbjct: 85 KKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQ-- 142
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM--ISRLPAT 265
+R + D L Q+ + L+L N++ + I +L L+ +N +S LP +
Sbjct: 143 IRSIPDSVGEL--QVIE----LNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQS 196
Query: 266 IGRISTLRYFTISSN 280
I S + + N
Sbjct: 197 ILSDSQICLLAVEGN 211
>BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 68.1 bits (159), Expect = 5e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 7e-08
Identities = 42/137 (30%), Positives = 69/137 (50%), Gaps = 8/137 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L LD+S N IE + NL +L L++N L + + + LL K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSL--QQLPETIGLL-----KNITTL 281
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 290 MQCR-LEYIDISSNKFD 305
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 10/138 (7%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 230
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGLLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 231 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 289
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 290 -MQCRLEYIDISSNKFDN 306
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 53.2 bits (122), Expect = 2e-06
Identities = 44/163 (26%), Positives = 72/163 (44%), Gaps = 8/163 (4%)
Query: 124 TAKNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNE 182
T +N + L + Q P GL + + +L + +L I L + LD S NE
Sbjct: 251 TCENLQDLLLSSNSLQQLPETIGLLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNE 310
Query: 183 IEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKA 242
+E LP G++ NL +N L W K + +L L SNKL LP+
Sbjct: 311 VEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNKLETLPEE 363
Query: 243 IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
+ ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 364 MGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 52.0 bits (119), Expect = 4e-06
Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L++ +E LP FGR+ L L L NQL + R +T+ L+ L
Sbjct: 137 LLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR------LTQ-LERL 189
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL SN+ +P+ + +L L + N ++ +P IG + L Y +S N ++ + +
Sbjct: 190 DLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGI 249
Query: 290 MQC-RLEYIDISSN 302
C L+ + +SSN
Sbjct: 250 STCENLQDLLLSSN 263
Score = 51.6 bits (118), Expect = 5e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 207 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGLLKNITTLK 282
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
>BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 68.1 bits (159), Expect = 5e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 10/138 (7%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 230
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPEPIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 231 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 289
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 290 -MQCRLEYIDISSNKFDN 306
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 3e-07
Identities = 42/138 (30%), Positives = 67/138 (48%), Gaps = 10/138 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGP-QITKTLKL 228
LK L LD+S N IE + NL +L L++N L + L P K +
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSL--------QQLPEPIGSLKNITT 280
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L + N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP
Sbjct: 281 LKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPE 340
Query: 289 LMQCR-LEYIDISSNKFD 305
+ + + + + SNK +
Sbjct: 341 IGSWKNITVLFLHSNKLE 358
Score = 52.0 bits (119), Expect = 4e-06
Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L++ +E LP FGR+ L L L NQL + R +T+ L+ L
Sbjct: 137 LLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR------LTQ-LERL 189
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL SN+ +P+ + +L L + N ++ +P IG + L Y +S N ++ + +
Sbjct: 190 DLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGI 249
Query: 290 MQC-RLEYIDISSN 302
C L+ + +SSN
Sbjct: 250 STCENLQDLLLSSN 263
Score = 52.0 bits (119), Expect = 4e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 207 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPEPIGSLKNITTLK 282
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 50.8 bits (116), Expect = 9e-06
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 235
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 236 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 33.9 bits (74), Expect = 1.0
Identities = 18/64 (28%), Positives = 36/64 (56%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
P G + + L+L KL ++ ++ L V++LS+N ++ LP F ++ L+ + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 202 ANNQ 205
++NQ
Sbjct: 399 SDNQ 402
>BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein.
Length = 633
Score = 68.1 bits (159), Expect = 5e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 10/138 (7%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 230
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 231 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 289
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 290 -MQCRLEYIDISSNKFDN 306
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L LD+S N IE + NL +L L++N L +G K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPET-----IGS--LKNITTL 281
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 290 MQCR-LEYIDISSNKFD 305
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 52.4 bits (120), Expect = 3e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 207 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLK 282
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 52.0 bits (119), Expect = 4e-06
Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L++ +E LP FGR+ L L L NQL + R +T+ L+ L
Sbjct: 137 LLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR------LTQ-LERL 189
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL SN+ +P+ + +L L + N ++ +P IG + L Y +S N ++ + +
Sbjct: 190 DLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGI 249
Query: 290 MQC-RLEYIDISSN 302
C L+ + +SSN
Sbjct: 250 STCENLQDLLLSSN 263
Score = 50.8 bits (116), Expect = 9e-06
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 235
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 236 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 33.9 bits (74), Expect = 1.0
Identities = 18/64 (28%), Positives = 36/64 (56%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
P G + + L+L KL ++ ++ L V++LS+N ++ LP F ++ L+ + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 202 ANNQ 205
++NQ
Sbjct: 399 SDNQ 402
>AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 1 protein.
Length = 734
Score = 68.1 bits (159), Expect = 5e-11
Identities = 55/172 (31%), Positives = 85/172 (49%), Gaps = 9/172 (5%)
Query: 132 KLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFG 191
KL R+ P L T+Q+ LS +L ++ L +L+L +N I +P
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 192 RMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ L+ L+L+ NQL L G LK+L ++NKLG LP+ I +L++L+
Sbjct: 141 NLQMLTYLNLSRNQLSALPAC----LCG----LPLKVLIASNNKLGSLPEEIGQLKQLME 192
Query: 252 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
L + N I+ LP IG++ +LR + N L+ LP L+ L D S NK
Sbjct: 193 LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK 244
>AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 1 protein.
Length = 734
Score = 68.1 bits (159), Expect = 5e-11
Identities = 55/172 (31%), Positives = 85/172 (49%), Gaps = 9/172 (5%)
Query: 132 KLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFG 191
KL R+ P L T+Q+ LS +L ++ L +L+L +N I +P
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 192 RMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ L+ L+L+ NQL L G LK+L ++NKLG LP+ I +L++L+
Sbjct: 141 NLQMLTYLNLSRNQLSALPAC----LCG----LPLKVLIASNNKLGSLPEEIGQLKQLME 192
Query: 252 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
L + N I+ LP IG++ +LR + N L+ LP L+ L D S NK
Sbjct: 193 LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNK 244
>AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein
protein.
Length = 1412
Score = 68.1 bits (159), Expect = 5e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 10/138 (7%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 230
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 231 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 289
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 290 -MQCRLEYIDISSNKFDN 306
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L LD+S N IE + NL +L L++N L +G K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPET-----IGS--LKNITTL 281
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 290 MQCR-LEYIDISSNKFD 305
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 52.4 bits (120), Expect = 3e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 207 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLK 282
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 52.0 bits (119), Expect = 4e-06
Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L++ +E LP FGR+ L L L NQL + R +T+ L+ L
Sbjct: 137 LLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR------LTQ-LERL 189
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL SN+ +P+ + +L L + N ++ +P IG + L Y +S N ++ + +
Sbjct: 190 DLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGI 249
Query: 290 MQC-RLEYIDISSN 302
C L+ + +SSN
Sbjct: 250 STCENLQDLLLSSN 263
Score = 50.8 bits (116), Expect = 9e-06
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 235
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 236 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 33.9 bits (74), Expect = 1.0
Identities = 18/64 (28%), Positives = 36/64 (56%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
P G + + L+L KL ++ ++ L V++LS+N ++ LP F ++ L+ + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 202 ANNQ 205
++NQ
Sbjct: 399 SDNQ 402
>AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein.
Length = 1601
Score = 68.1 bits (159), Expect = 5e-11
Identities = 43/137 (31%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L LS+NEI++LPPE L EL ++ N + + + + K L++
Sbjct: 29 LLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRND--IPEIPE-----SIKFCKALEIA 81
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
D + N L LP +L L L ND + LP +G ++ L + N L+SLP SL
Sbjct: 82 DFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASL 141
Query: 290 -MQCRLEYIDISSNKFD 305
+LE +D+ N +
Sbjct: 142 SFLVKLEQLDLGGNDLE 158
Score = 60.1 bits (139), Expect = 1e-08
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 14/178 (7%)
Query: 133 LVISDRSQFPAKGLP------RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKL 186
L I+D S P LP R+L L L+ + L D+ L +L L+L N ++ L
Sbjct: 78 LEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSL 137
Query: 187 PPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKL 246
P + L +L L N L V + D LG L+ L L N+L LP + L
Sbjct: 138 PASLSFLVKLEQLDLGGNDLEV--LPD---TLGA--LPNLRELWLDRNQLSALPPELGNL 190
Query: 247 EKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
+LV L ++N + LPA +G + L +S N L+ LP + Q + L + + N+
Sbjct: 191 RRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNR 248
Score = 58.0 bits (134), Expect = 6e-08
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 17/174 (9%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
L+ L+L +L ++ L+ L LD+S N +E+LP E G + L++L L+ N L
Sbjct: 170 LRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRL 229
Query: 207 --GVRGVVDWRWLLGPQ-----ITKT------LKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G+ + L Q +T+ L L LT N L LP+++ KL KL L
Sbjct: 230 PDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLN 289
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKFDN 306
+ N + LP IG L ++ N L LP L L +D++ N+ +
Sbjct: 290 VDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQS 343
Score = 52.4 bits (120), Expect = 3e-06
Identities = 49/165 (29%), Positives = 72/165 (43%), Gaps = 7/165 (4%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L LS L I LK L++L + N + ++ G NLSEL L N L
Sbjct: 216 LTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLL--- 272
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
+ LG ++TK L L++ N L LP I L L DN ++ LP +
Sbjct: 273 --MALPRSLG-KLTK-LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 328
Query: 270 STLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTSD 314
+ L ++ N LQSLP +L L+ + ++ N+ T D
Sbjct: 329 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPMLRFQTED 373
Score = 44.8 bits (101), Expect = 6e-04
Identities = 37/140 (26%), Positives = 61/140 (43%), Gaps = 7/140 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L LS ++ ++ L LD+S N+I ++P L + N L
Sbjct: 32 LRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLS-- 89
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
R G ++L L L L LP + L LVTL+ +N++ LPA++ +
Sbjct: 90 -----RLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFL 144
Query: 270 STLRYFTISSNELQSLPCSL 289
L + N+L+ LP +L
Sbjct: 145 VKLEQLDLGGNDLEVLPDTL 164
Score = 35.5 bits (78), Expect = 0.34
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 244 WKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
++L L L +DN I RLP + L +S N++ +P S+ C+ LE D S N
Sbjct: 27 FRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGN 86
>AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting protein
ERBIN protein.
Length = 1371
Score = 68.1 bits (159), Expect = 5e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 10/138 (7%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 230
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 231 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 289
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 290 -MQCRLEYIDISSNKFDN 306
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L LD+S N IE + NL +L L++N L +G K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPET-----IGS--LKNITTL 281
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 290 MQCR-LEYIDISSNKFD 305
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 52.4 bits (120), Expect = 3e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 207 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLK 282
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 52.0 bits (119), Expect = 4e-06
Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L++ +E LP FGR+ L L L NQL + R +T+ L+ L
Sbjct: 137 LLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR------LTQ-LERL 189
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL SN+ +P+ + +L L + N ++ +P IG + L Y +S N ++ + +
Sbjct: 190 DLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGI 249
Query: 290 MQC-RLEYIDISSN 302
C L+ + +SSN
Sbjct: 250 STCENLQDLLLSSN 263
Score = 50.8 bits (116), Expect = 9e-06
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 235
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 236 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 33.9 bits (74), Expect = 1.0
Identities = 18/64 (28%), Positives = 36/64 (56%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
P G + + L+L KL ++ ++ L V++LS+N ++ LP F ++ L+ + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 202 ANNQ 205
++NQ
Sbjct: 399 SDNQ 402
>AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein.
Length = 1371
Score = 68.1 bits (159), Expect = 5e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 10/138 (7%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 230
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 231 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 289
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 290 -MQCRLEYIDISSNKFDN 306
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L LD+S N IE + NL +L L++N L +G K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPET-----IGS--LKNITTL 281
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 290 MQCR-LEYIDISSNKFD 305
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 52.4 bits (120), Expect = 3e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 207 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLK 282
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 52.0 bits (119), Expect = 4e-06
Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L++ +E LP FGR+ L L L NQL + R +T+ L+ L
Sbjct: 137 LLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR------LTQ-LERL 189
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL SN+ +P+ + +L L + N ++ +P IG + L Y +S N ++ + +
Sbjct: 190 DLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGI 249
Query: 290 MQC-RLEYIDISSN 302
C L+ + +SSN
Sbjct: 250 STCENLQDLLLSSN 263
Score = 50.8 bits (116), Expect = 9e-06
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 235
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 236 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 33.9 bits (74), Expect = 1.0
Identities = 18/64 (28%), Positives = 36/64 (56%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
P G + + L+L KL ++ ++ L V++LS+N ++ LP F ++ L+ + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 202 ANNQ 205
++NQ
Sbjct: 399 SDNQ 402
>BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein.
Length = 763
Score = 67.7 bits (158), Expect = 7e-11
Identities = 55/172 (31%), Positives = 85/172 (49%), Gaps = 9/172 (5%)
Query: 132 KLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFG 191
KL R+ P L T+Q+ LS +L ++ L +L+L +N I +P
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 192 RMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ L+ L+L+ NQL L G LK+L ++NKLG LP+ I +L++L+
Sbjct: 141 NLQMLTYLNLSRNQLSALPAC----LCG----LPLKVLIASNNKLGSLPEEIGQLKQLME 192
Query: 252 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
L + N I+ LP IG++ +LR + N L+ LP L+ L D S NK
Sbjct: 193 LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDFSCNK 244
>BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein.
Length = 696
Score = 67.7 bits (158), Expect = 7e-11
Identities = 55/172 (31%), Positives = 85/172 (49%), Gaps = 9/172 (5%)
Query: 132 KLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFG 191
KL R+ P L T+Q+ LS +L ++ L +L+L +N I +P
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 192 RMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ L+ L+L+ NQL L G LK+L ++NKLG LP+ I +L++L+
Sbjct: 141 NLQMLTYLNLSRNQLSALPAC----LCG----LPLKVLIASNNKLGSLPEEIGQLKQLME 192
Query: 252 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
L + N I+ LP IG++ +LR + N L+ LP L+ L D S NK
Sbjct: 193 LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDFSCNK 244
>AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isoform B
protein.
Length = 728
Score = 67.7 bits (158), Expect = 7e-11
Identities = 55/172 (31%), Positives = 85/172 (49%), Gaps = 9/172 (5%)
Query: 132 KLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFG 191
KL R+ P L T+Q+ LS +L ++ L +L+L +N I +P
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 192 RMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ L+ L+L+ NQL L G LK+L ++NKLG LP+ I +L++L+
Sbjct: 141 NLQMLTYLNLSRNQLSALPAC----LCG----LPLKVLIASNNKLGSLPEEIGQLKQLME 192
Query: 252 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
L + N I+ LP IG++ +LR + N L+ LP L+ L D S NK
Sbjct: 193 LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDFSCNK 244
>AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isoform a
protein.
Length = 696
Score = 67.7 bits (158), Expect = 7e-11
Identities = 55/172 (31%), Positives = 85/172 (49%), Gaps = 9/172 (5%)
Query: 132 KLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFG 191
KL R+ P L T+Q+ LS +L ++ L +L+L +N I +P
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 192 RMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ L+ L+L+ NQL L G LK+L ++NKLG LP+ I +L++L+
Sbjct: 141 NLQMLTYLNLSRNQLSALPAC----LCG----LPLKVLIASNNKLGSLPEEIGQLKQLME 192
Query: 252 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
L + N I+ LP IG++ +LR + N L+ LP L+ L D S NK
Sbjct: 193 LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDFSCNK 244
>AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein.
Length = 793
Score = 67.7 bits (158), Expect = 7e-11
Identities = 55/172 (31%), Positives = 85/172 (49%), Gaps = 9/172 (5%)
Query: 132 KLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFG 191
KL R+ P L T+Q+ LS +L ++ L +L+L +N I +P
Sbjct: 147 KLKEFPRTAAPGHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 205
Query: 192 RMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVT 251
+ L+ L+L+ NQL L G LK+L ++NKLG LP+ I +L++L+
Sbjct: 206 NLQMLTYLNLSRNQLSALPAC----LCG----LPLKVLIASNNKLGSLPEEIGQLKQLME 257
Query: 252 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
L + N I+ LP IG++ +LR + N L+ LP L+ L D S NK
Sbjct: 258 LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVKFDFSCNK 309
>BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 66.9 bits (156), Expect = 1e-10
Identities = 49/158 (31%), Positives = 78/158 (49%), Gaps = 9/158 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L +LYL ++ +DI L L++L + N+I++LP E G + NL L +A+NQL
Sbjct: 193 SLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEH 252
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
QIT LDL N+L LP I L L L N +S +P ++ +
Sbjct: 253 LPKEIGNCT---QITN----LDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 269 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNKF 304
S L + +N + +LP SL+ +L + ++ N F
Sbjct: 306 CSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCF 343
Score = 63.3 bits (147), Expect = 1e-09
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 207
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 403 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 463 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 268 RISTLRYFTISSN-ELQSLPCSLMQC 292
+ L ++ N L SLP L C
Sbjct: 515 TLENLEELYLNDNPNLHSLPFELALC 540
Score = 62.1 bits (144), Expect = 3e-09
Identities = 57/211 (27%), Positives = 101/211 (47%), Gaps = 20/211 (9%)
Query: 110 EKALHLSPLSSLSVTAKNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDIL 168
++++H+ P S +T + L + PA+ G L +L LS L + +
Sbjct: 109 KRSIHILPSSIKELTQLTE--LYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLD 166
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWL------ 217
LK L +LDL +N++ ++P R+ +L+ L+L N++ ++ + L
Sbjct: 167 NLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENK 226
Query: 218 ---LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTL 272
L +I + L LD+ N+L HLPK I ++ L N + LP TIG +S+L
Sbjct: 227 IKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSL 286
Query: 273 RYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
+ N L ++P SL +C LE +++ +N
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENN 317
Score = 60.9 bits (141), Expect = 8e-09
Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 8/155 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L LYL KL + ++ L +L L LS N + LP + L L L +N+L
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREI 184
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
V +R +L L L N++ + K I L KL L +N I +LPA IG +
Sbjct: 185 PSVVYR-------LDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGEL 237
Query: 270 STLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
L ++ N+L+ LP + C ++ +D+ N+
Sbjct: 238 CNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNE 272
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 218
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 219 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 274
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 498
Query: 275 FTISSNELQSLP 286
+ N L LP
Sbjct: 499 LGLGENLLTHLP 510
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/148 (28%), Positives = 73/148 (49%), Gaps = 17/148 (11%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLLGPQIT------- 223
LDLS I LP + L+EL+L +N+L V +V+ L + +
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 224 ----KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
K L++LDL NKL +P +++L+ L TL N I+ + I +S L +I
Sbjct: 165 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 224
Query: 280 NELQSLPCSLMQ-CRLEYIDISSNKFDN 306
N+++ LP + + C L +D++ N+ ++
Sbjct: 225 NKIKQLPAEIGELCNLITLDVAHNQLEH 252
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L + K+ +I L +L LD+++N++E LP E G ++ L L +N+L
Sbjct: 217 LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNEL--- 273
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP-ATIGR 268
+D +G +L L L N+L +P+++ K L L +N IS LP + +
Sbjct: 274 --LDLPDTIGN--LSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSS 329
Query: 269 ISTLRYFTISSNELQSLP 286
+ L T++ N Q P
Sbjct: 330 LVKLNSLTLARNCFQLYP 347
Score = 42.3 bits (95), Expect = 0.003
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L L++ N+L LP +V L N ++++P + + +L +S+N L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 284 SLPCSLMQCR-LEYIDISSNKFDNKQN 309
LP L R L +D+ NK ++ N
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPN 465
Score = 37.9 bits (84), Expect = 0.064
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
+ LQ L L+ +L R I L +L L L N + LP E G + NL EL+L +N
Sbjct: 471 KDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN 527
>BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 66.9 bits (156), Expect = 1e-10
Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 13/156 (8%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+SLY S KL + + L+ L LD+S N I +P E G + NL LH+ N++
Sbjct: 706 KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVD 765
Query: 208 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 265
+ L Q+ K +KL L+L N + LP+ + +L +L L+ N + RLPA
Sbjct: 766 I---------LPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQ 816
Query: 266 IGRISTLRY--FTISSNELQSLPCSLMQCRLEYIDI 299
+G+ L+ + + +LP + + + I+I
Sbjct: 817 LGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINI 852
Score = 65.3 bits (152), Expect = 4e-10
Identities = 46/147 (31%), Positives = 72/147 (48%), Gaps = 7/147 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L L L K+ I +K+L L SNN++E LP + L L ++ N +
Sbjct: 683 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 742
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + +G + + L+ L +T NK+ LPK ++K KL TL N I+ LP +G
Sbjct: 743 MIPIE-----IG--LLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVG 795
Query: 268 RISTLRYFTISSNELQSLPCSLMQCRL 294
++S L + N L LP L QCR+
Sbjct: 796 QLSQLTQLELKGNCLDRLPAQLGQCRM 822
Score = 61.7 bits (143), Expect = 5e-09
Identities = 38/137 (27%), Positives = 73/137 (53%), Gaps = 6/137 (4%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
+ ++A L+L N E+E++P ++NL EL L +N +R + + ++ Q K L L
Sbjct: 634 MMNVAELELQNCELERIPHAIFSLSNLQELDLKSNN--IRTIEE---IISFQHLKRLTCL 688
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
L NK+ +P +I ++ L +L ++N + LP + + LR +S N + +P +
Sbjct: 689 KLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEI 748
Query: 290 -MQCRLEYIDISSNKFD 305
+ L+++ I+ NK D
Sbjct: 749 GLLQNLQHLHITGNKVD 765
>AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein.
Length = 501
Score = 66.9 bits (156), Expect = 1e-10
Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 13/156 (8%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+SLY S KL + + L+ L LD+S N I +P E G + NL LH+ N++
Sbjct: 349 KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVD 408
Query: 208 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 265
+ L Q+ K +KL L+L N + LP+ + +L +L L+ N + RLPA
Sbjct: 409 I---------LPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQ 459
Query: 266 IGRISTLRY--FTISSNELQSLPCSLMQCRLEYIDI 299
+G+ L+ + + +LP + + + I+I
Sbjct: 460 LGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINI 495
Score = 65.3 bits (152), Expect = 4e-10
Identities = 46/147 (31%), Positives = 72/147 (48%), Gaps = 7/147 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L L L K+ I +K+L L SNN++E LP + L L ++ N +
Sbjct: 326 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 385
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + +G + + L+ L +T NK+ LPK ++K KL TL N I+ LP +G
Sbjct: 386 MIPIE-----IG--LLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVG 438
Query: 268 RISTLRYFTISSNELQSLPCSLMQCRL 294
++S L + N L LP L QCR+
Sbjct: 439 QLSQLTQLELKGNCLDRLPAQLGQCRM 465
Score = 61.7 bits (143), Expect = 5e-09
Identities = 38/137 (27%), Positives = 73/137 (53%), Gaps = 6/137 (4%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
+ ++A L+L N E+E++P ++NL EL L +N +R + + ++ Q K L L
Sbjct: 277 MMNVAELELQNCELERIPHAIFSLSNLQELDLKSNN--IRTIEE---IISFQHLKRLTCL 331
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
L NK+ +P +I ++ L +L ++N + LP + + LR +S N + +P +
Sbjct: 332 KLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEI 391
Query: 290 -MQCRLEYIDISSNKFD 305
+ L+++ I+ NK D
Sbjct: 392 GLLQNLQHLHITGNKVD 408
>AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 66.9 bits (156), Expect = 1e-10
Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 13/156 (8%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+SLY S KL + + L+ L LD+S N I +P E G + NL LH+ N++
Sbjct: 706 KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVD 765
Query: 208 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 265
+ L Q+ K +KL L+L N + LP+ + +L +L L+ N + RLPA
Sbjct: 766 I---------LPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQ 816
Query: 266 IGRISTLRY--FTISSNELQSLPCSLMQCRLEYIDI 299
+G+ L+ + + +LP + + + I+I
Sbjct: 817 LGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINI 852
Score = 65.3 bits (152), Expect = 4e-10
Identities = 46/147 (31%), Positives = 72/147 (48%), Gaps = 7/147 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L L L K+ I +K+L L SNN++E LP + L L ++ N +
Sbjct: 683 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 742
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + +G + + L+ L +T NK+ LPK ++K KL TL N I+ LP +G
Sbjct: 743 MIPIE-----IG--LLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVG 795
Query: 268 RISTLRYFTISSNELQSLPCSLMQCRL 294
++S L + N L LP L QCR+
Sbjct: 796 QLSQLTQLELKGNCLDRLPAQLGQCRM 822
Score = 61.7 bits (143), Expect = 5e-09
Identities = 38/137 (27%), Positives = 73/137 (53%), Gaps = 6/137 (4%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
+ ++A L+L N E+E++P ++NL EL L +N +R + + ++ Q K L L
Sbjct: 634 MMNVAELELQNCELERIPHAIFSLSNLQELDLKSNN--IRTIEE---IISFQHLKRLTCL 688
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
L NK+ +P +I ++ L +L ++N + LP + + LR +S N + +P +
Sbjct: 689 KLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEI 748
Query: 290 -MQCRLEYIDISSNKFD 305
+ L+++ I+ NK D
Sbjct: 749 GLLQNLQHLHITGNKVD 765
>AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 66.9 bits (156), Expect = 1e-10
Identities = 49/158 (31%), Positives = 78/158 (49%), Gaps = 9/158 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L +LYL ++ +DI L L++L + N+I++LP E G + NL L +A+NQL
Sbjct: 193 SLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEH 252
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
QIT LDL N+L LP I L L L N +S +P ++ +
Sbjct: 253 LPKEIGNCT---QITN----LDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 269 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNKF 304
S L + +N + +LP SL+ +L + ++ N F
Sbjct: 306 CSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCF 343
Score = 63.3 bits (147), Expect = 1e-09
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 207
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 403 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 463 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 268 RISTLRYFTISSN-ELQSLPCSLMQC 292
+ L ++ N L SLP L C
Sbjct: 515 TLENLEELYLNDNPNLHSLPFELALC 540
Score = 62.1 bits (144), Expect = 3e-09
Identities = 57/211 (27%), Positives = 101/211 (47%), Gaps = 20/211 (9%)
Query: 110 EKALHLSPLSSLSVTAKNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDIL 168
++++H+ P S +T + L + PA+ G L +L LS L + +
Sbjct: 109 KRSIHILPSSIKELTQLTE--LYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLD 166
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWL------ 217
LK L +LDL +N++ ++P R+ +L+ L+L N++ ++ + L
Sbjct: 167 NLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENK 226
Query: 218 ---LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTL 272
L +I + L LD+ N+L HLPK I ++ L N + LP TIG +S+L
Sbjct: 227 IKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSL 286
Query: 273 RYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
+ N L ++P SL +C LE +++ +N
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENN 317
Score = 60.9 bits (141), Expect = 8e-09
Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 8/155 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L LYL KL + ++ L +L L LS N + LP + L L L +N+L
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREI 184
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
V +R +L L L N++ + K I L KL L +N I +LPA IG +
Sbjct: 185 PSVVYR-------LDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGEL 237
Query: 270 STLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
L ++ N+L+ LP + C ++ +D+ N+
Sbjct: 238 CNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNE 272
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 218
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 219 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 274
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 498
Query: 275 FTISSNELQSLP 286
+ N L LP
Sbjct: 499 LGLGENLLTHLP 510
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/148 (28%), Positives = 73/148 (49%), Gaps = 17/148 (11%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLLGPQIT------- 223
LDLS I LP + L+EL+L +N+L V +V+ L + +
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 224 ----KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
K L++LDL NKL +P +++L+ L TL N I+ + I +S L +I
Sbjct: 165 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 224
Query: 280 NELQSLPCSLMQ-CRLEYIDISSNKFDN 306
N+++ LP + + C L +D++ N+ ++
Sbjct: 225 NKIKQLPAEIGELCNLITLDVAHNQLEH 252
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L + K+ +I L +L LD+++N++E LP E G ++ L L +N+L
Sbjct: 217 LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNEL--- 273
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP-ATIGR 268
+D +G +L L L N+L +P+++ K L L +N IS LP + +
Sbjct: 274 --LDLPDTIGN--LSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSS 329
Query: 269 ISTLRYFTISSNELQSLP 286
+ L T++ N Q P
Sbjct: 330 LVKLNSLTLARNCFQLYP 347
Score = 42.3 bits (95), Expect = 0.003
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L L++ N+L LP +V L N ++++P + + +L +S+N L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 284 SLPCSLMQCR-LEYIDISSNKFDNKQN 309
LP L R L +D+ NK ++ N
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPN 465
Score = 37.9 bits (84), Expect = 0.064
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
+ LQ L L+ +L R I L +L L L N + LP E G + NL EL+L +N
Sbjct: 471 KDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN 527
>AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ10470 fis, clone NT2RP2000032, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 682
Score = 66.9 bits (156), Expect = 1e-10
Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 13/156 (8%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+SLY S KL + + L+ L LD+S N I +P E G + NL LH+ N++
Sbjct: 530 KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVD 589
Query: 208 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 265
+ L Q+ K +KL L+L N + LP+ + +L +L L+ N + RLPA
Sbjct: 590 I---------LPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQ 640
Query: 266 IGRISTLRY--FTISSNELQSLPCSLMQCRLEYIDI 299
+G+ L+ + + +LP + + + I+I
Sbjct: 641 LGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINI 676
Score = 65.3 bits (152), Expect = 4e-10
Identities = 46/147 (31%), Positives = 72/147 (48%), Gaps = 7/147 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L L L K+ I +K+L L SNN++E LP + L L ++ N +
Sbjct: 507 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 566
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + +G + + L+ L +T NK+ LPK ++K KL TL N I+ LP +G
Sbjct: 567 MIPIE-----IG--LLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVG 619
Query: 268 RISTLRYFTISSNELQSLPCSLMQCRL 294
++S L + N L LP L QCR+
Sbjct: 620 QLSQLTQLELKGNCLDRLPAQLGQCRM 646
Score = 61.7 bits (143), Expect = 5e-09
Identities = 38/137 (27%), Positives = 73/137 (53%), Gaps = 6/137 (4%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
+ ++A L+L N E+E++P ++NL EL L +N +R + + ++ Q K L L
Sbjct: 458 MMNVAELELQNCELERIPHAIFSLSNLQELDLKSNN--IRTIEE---IISFQHLKRLTCL 512
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
L NK+ +P +I ++ L +L ++N + LP + + LR +S N + +P +
Sbjct: 513 KLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEI 572
Query: 290 -MQCRLEYIDISSNKFD 305
+ L+++ I+ NK D
Sbjct: 573 GLLQNLQHLHITGNKVD 589
>AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR-8
protein.
Length = 582
Score = 66.9 bits (156), Expect = 1e-10
Identities = 49/158 (31%), Positives = 78/158 (49%), Gaps = 9/158 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L +LYL ++ +DI L L++L + N+I++LP E G + NL L +A+NQL
Sbjct: 193 SLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEH 252
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
QIT LDL N+L LP I L L L N +S +P ++ +
Sbjct: 253 LPKEIGNCT---QITN----LDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 269 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNKF 304
S L + +N + +LP SL+ +L + ++ N F
Sbjct: 306 CSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCF 343
Score = 63.3 bits (147), Expect = 1e-09
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 207
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 403 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 463 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 268 RISTLRYFTISSN-ELQSLPCSLMQC 292
+ L ++ N L SLP L C
Sbjct: 515 TLENLEELYLNDNPNLHSLPFELALC 540
Score = 62.1 bits (144), Expect = 3e-09
Identities = 57/211 (27%), Positives = 101/211 (47%), Gaps = 20/211 (9%)
Query: 110 EKALHLSPLSSLSVTAKNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDIL 168
++++H+ P S +T + L + PA+ G L +L LS L + +
Sbjct: 109 KRSIHILPSSIKELTQLTE--LYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLD 166
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWL------ 217
LK L +LDL +N++ ++P R+ +L+ L+L N++ ++ + L
Sbjct: 167 NLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENK 226
Query: 218 ---LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTL 272
L +I + L LD+ N+L HLPK I ++ L N + LP TIG +S+L
Sbjct: 227 IKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSL 286
Query: 273 RYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
+ N L ++P SL +C LE +++ +N
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENN 317
Score = 60.9 bits (141), Expect = 8e-09
Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 8/155 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L LYL KL + ++ L +L L LS N + LP + L L L +N+L
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREI 184
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
V +R +L L L N++ + K I L KL L +N I +LPA IG +
Sbjct: 185 PSVVYR-------LDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGEL 237
Query: 270 STLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
L ++ N+L+ LP + C ++ +D+ N+
Sbjct: 238 CNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNE 272
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 218
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 219 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 274
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 498
Query: 275 FTISSNELQSLP 286
+ N L LP
Sbjct: 499 LGLGENLLTHLP 510
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/148 (28%), Positives = 73/148 (49%), Gaps = 17/148 (11%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLLGPQIT------- 223
LDLS I LP + L+EL+L +N+L V +V+ L + +
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 224 ----KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
K L++LDL NKL +P +++L+ L TL N I+ + I +S L +I
Sbjct: 165 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 224
Query: 280 NELQSLPCSLMQ-CRLEYIDISSNKFDN 306
N+++ LP + + C L +D++ N+ ++
Sbjct: 225 NKIKQLPAEIGELCNLITLDVAHNQLEH 252
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L + K+ +I L +L LD+++N++E LP E G ++ L L +N+L
Sbjct: 217 LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNEL--- 273
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP-ATIGR 268
+D +G +L L L N+L +P+++ K L L +N IS LP + +
Sbjct: 274 --LDLPDTIGN--LSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSS 329
Query: 269 ISTLRYFTISSNELQSLP 286
+ L T++ N Q P
Sbjct: 330 LVKLNSLTLARNCFQLYP 347
Score = 42.3 bits (95), Expect = 0.003
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L L++ N+L LP +V L N ++++P + + +L +S+N L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 284 SLPCSLMQCR-LEYIDISSNKFDNKQN 309
LP L R L +D+ NK ++ N
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPN 465
Score = 37.9 bits (84), Expect = 0.064
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
+ LQ L L+ +L R I L +L L L N + LP E G + NL EL+L +N
Sbjct: 471 KDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN 527
>AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat
protein SHOC-2 protein.
Length = 582
Score = 66.9 bits (156), Expect = 1e-10
Identities = 49/158 (31%), Positives = 78/158 (49%), Gaps = 9/158 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L +LYL ++ +DI L L++L + N+I++LP E G + NL L +A+NQL
Sbjct: 193 SLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEH 252
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
QIT LDL N+L LP I L L L N +S +P ++ +
Sbjct: 253 LPKEIGNCT---QITN----LDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 269 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNKF 304
S L + +N + +LP SL+ +L + ++ N F
Sbjct: 306 CSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCF 343
Score = 63.3 bits (147), Expect = 1e-09
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 207
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 403 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 463 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 268 RISTLRYFTISSN-ELQSLPCSLMQC 292
+ L ++ N L SLP L C
Sbjct: 515 TLENLEELYLNDNPNLHSLPFELALC 540
Score = 62.1 bits (144), Expect = 3e-09
Identities = 57/211 (27%), Positives = 101/211 (47%), Gaps = 20/211 (9%)
Query: 110 EKALHLSPLSSLSVTAKNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDIL 168
++++H+ P S +T + L + PA+ G L +L LS L + +
Sbjct: 109 KRSIHILPSSIKELTQLTE--LYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLD 166
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWL------ 217
LK L +LDL +N++ ++P R+ +L+ L+L N++ ++ + L
Sbjct: 167 NLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENK 226
Query: 218 ---LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTL 272
L +I + L LD+ N+L HLPK I ++ L N + LP TIG +S+L
Sbjct: 227 IKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSL 286
Query: 273 RYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
+ N L ++P SL +C LE +++ +N
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENN 317
Score = 60.9 bits (141), Expect = 8e-09
Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 8/155 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L LYL KL + ++ L +L L LS N + LP + L L L +N+L
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREI 184
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
V +R +L L L N++ + K I L KL L +N I +LPA IG +
Sbjct: 185 PSVVYR-------LDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGEL 237
Query: 270 STLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
L ++ N+L+ LP + C ++ +D+ N+
Sbjct: 238 CNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNE 272
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 218
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 219 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 274
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 498
Query: 275 FTISSNELQSLP 286
+ N L LP
Sbjct: 499 LGLGENLLTHLP 510
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/148 (28%), Positives = 73/148 (49%), Gaps = 17/148 (11%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLLGPQIT------- 223
LDLS I LP + L+EL+L +N+L V +V+ L + +
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 224 ----KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
K L++LDL NKL +P +++L+ L TL N I+ + I +S L +I
Sbjct: 165 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 224
Query: 280 NELQSLPCSLMQ-CRLEYIDISSNKFDN 306
N+++ LP + + C L +D++ N+ ++
Sbjct: 225 NKIKQLPAEIGELCNLITLDVAHNQLEH 252
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L + K+ +I L +L LD+++N++E LP E G ++ L L +N+L
Sbjct: 217 LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNEL--- 273
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP-ATIGR 268
+D +G +L L L N+L +P+++ K L L +N IS LP + +
Sbjct: 274 --LDLPDTIGN--LSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSS 329
Query: 269 ISTLRYFTISSNELQSLP 286
+ L T++ N Q P
Sbjct: 330 LVKLNSLTLARNCFQLYP 347
Score = 42.3 bits (95), Expect = 0.003
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L L++ N+L LP +V L N ++++P + + +L +S+N L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 284 SLPCSLMQCR-LEYIDISSNKFDNKQN 309
LP L R L +D+ NK ++ N
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPN 465
Score = 37.9 bits (84), Expect = 0.064
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
+ LQ L L+ +L R I L +L L L N + LP E G + NL EL+L +N
Sbjct: 471 KDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN 527
>AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein.
Length = 584
Score = 66.9 bits (156), Expect = 1e-10
Identities = 49/158 (31%), Positives = 78/158 (49%), Gaps = 9/158 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L +LYL ++ +DI L L++L + N+I++LP E G + NL L +A+NQL
Sbjct: 195 SLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEH 254
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
QIT LDL N+L LP I L L L N +S +P ++ +
Sbjct: 255 LPKEIGNCT---QITN----LDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 307
Query: 269 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNKF 304
S L + +N + +LP SL+ +L + ++ N F
Sbjct: 308 CSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCF 345
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 207
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 405 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 464
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 465 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 516
Query: 268 RISTLRYFTISSN-ELQSLPCSLMQC 292
+ L ++ N L SLP L C
Sbjct: 517 TLENLEELYLNDNPNLHSLPLELALC 542
Score = 62.1 bits (144), Expect = 3e-09
Identities = 57/211 (27%), Positives = 101/211 (47%), Gaps = 20/211 (9%)
Query: 110 EKALHLSPLSSLSVTAKNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDIL 168
++++H+ P S +T + L + PA+ G L +L LS L + +
Sbjct: 111 KRSIHILPSSIKELTQLTE--LYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLD 168
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWL------ 217
LK L +LDL +N++ ++P R+ +L+ L+L N++ ++ + L
Sbjct: 169 NLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENK 228
Query: 218 ---LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTL 272
L +I + L LD+ N+L HLPK I ++ L N + LP TIG +S+L
Sbjct: 229 IKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSL 288
Query: 273 RYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
+ N L ++P SL +C LE +++ +N
Sbjct: 289 SRLGLRYNRLSAIPRSLAKCSALEELNLENN 319
Score = 60.9 bits (141), Expect = 8e-09
Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 8/155 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L LYL KL + ++ L +L L LS N + LP + L L L +N+L
Sbjct: 127 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREI 186
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
V +R +L L L N++ + K I L KL L +N I +LPA IG +
Sbjct: 187 PSVVYR-------LDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGEL 239
Query: 270 STLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
L ++ N+L+ LP + C ++ +D+ N+
Sbjct: 240 CNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNE 274
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 218
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 381 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 440
Query: 219 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 274
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 441 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 500
Query: 275 FTISSNELQSLP 286
+ N L LP
Sbjct: 501 LGLGENLLTHLP 512
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/148 (28%), Positives = 73/148 (49%), Gaps = 17/148 (11%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLLGPQIT------- 223
LDLS I LP + L+EL+L +N+L V +V+ L + +
Sbjct: 107 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 166
Query: 224 ----KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
K L++LDL NKL +P +++L+ L TL N I+ + I +S L +I
Sbjct: 167 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 226
Query: 280 NELQSLPCSLMQ-CRLEYIDISSNKFDN 306
N+++ LP + + C L +D++ N+ ++
Sbjct: 227 NKIKQLPAEIGELCNLITLDVAHNQLEH 254
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L + K+ +I L +L LD+++N++E LP E G ++ L L +N+L
Sbjct: 219 LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNEL--- 275
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP-ATIGR 268
+D +G +L L L N+L +P+++ K L L +N IS LP + +
Sbjct: 276 --LDLPDTIGN--LSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSS 331
Query: 269 ISTLRYFTISSNELQSLP 286
+ L T++ N Q P
Sbjct: 332 LVKLNSLTLARNCFQLYP 349
Score = 42.3 bits (95), Expect = 0.003
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L L++ N+L LP +V L N ++++P + + +L +S+N L+
Sbjct: 381 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 440
Query: 284 SLPCSLMQCR-LEYIDISSNKFDNKQN 309
LP L R L +D+ NK ++ N
Sbjct: 441 KLPHGLGNLRKLRELDLEENKLESLPN 467
Score = 37.9 bits (84), Expect = 0.064
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
+ LQ L L+ +L R I L +L L L N + LP E G + NL EL+L +N
Sbjct: 473 KDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN 529
>BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein.
Length = 1367
Score = 65.3 bits (152), Expect = 4e-10
Identities = 42/158 (26%), Positives = 80/158 (50%), Gaps = 8/158 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
G+ ++ + + K L +++ + N + LP +L L L ND + LPA
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFD 158
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 304
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 7e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 10/138 (7%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 230
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 231 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 289
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 290 -MQCRLEYIDISSNKFDN 306
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
LK L LD+S N IE + NL +L L++N L +G K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPET-----IGS--LKNITTL 281
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 290 MQCR-LEYIDISSNKFD 305
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 52.4 bits (120), Expect = 3e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 206
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 207 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLK 282
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 50.8 bits (116), Expect = 9e-06
Identities = 46/170 (27%), Positives = 83/170 (48%), Gaps = 17/170 (10%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL-------- 201
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L
Sbjct: 94 LRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFL 153
Query: 202 -AN-NQLGVRGVVDWRWLLGPQITKT------LKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
AN ++L +++ R + KT L+ LDL SN+ +P+ + +L L
Sbjct: 154 PANFDRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFW 213
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
+ N ++ +P IG + L Y +S N ++ + + C L+ + +SSN
Sbjct: 214 MDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN 263
Score = 50.8 bits (116), Expect = 9e-06
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 176 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 235
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 236 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 33.9 bits (74), Expect = 1.0
Identities = 18/64 (28%), Positives = 36/64 (56%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
P G + + L+L KL ++ ++ L V++LS+N ++ LP F ++ L+ + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 202 ANNQ 205
++NQ
Sbjct: 399 SDNQ 402
>BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats and
death domain containing protein.
Length = 893
Score = 65.3 bits (152), Expect = 4e-10
Identities = 52/144 (36%), Positives = 70/144 (48%), Gaps = 8/144 (5%)
Query: 160 LCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLG 219
L N + L HLA LDLS N +E LP +M L L L++N L + LG
Sbjct: 114 LTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLS-----ELPEALG 168
Query: 220 PQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
L L +T N+L LP A+ L L L + N++ LP IG + +L ++S
Sbjct: 169 A--LPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLAS 226
Query: 280 NELQSLPCSLMQCR-LEYIDISSN 302
N LQSLP SL R L + + SN
Sbjct: 227 NRLQSLPASLAGLRSLRLLVLHSN 250
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 11/145 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L +L LS L + L L L +++N ++ LPP G ++ L L L+ N L
Sbjct: 148 RGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLD 207
Query: 208 VRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 265
L P+I +L L+L SN+L LP ++ L L L + N+++ +PA
Sbjct: 208 T---------LPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPAD 258
Query: 266 IGRISTLRYFTISSNELQSLPCSLM 290
+ R+ L + N+L+ LP L+
Sbjct: 259 LARLPLLTRLDLRDNQLRDLPPELL 283
Score = 56.0 bits (129), Expect = 2e-07
Identities = 43/138 (31%), Positives = 68/138 (49%), Gaps = 8/138 (5%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L ++ L L LS+N + +LP G + L+ L + +N+L LG TL
Sbjct: 144 VLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPA-----LGA--LSTL 196
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+ LDL+ N L LP I L L+ L N + LPA++ + +LR + SN L S+P
Sbjct: 197 QRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVP 256
Query: 287 CSLMQC-RLEYIDISSNK 303
L + L +D+ N+
Sbjct: 257 ADLARLPLLTRLDLRDNQ 274
Score = 31.5 bits (68), Expect = 5.6
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 7/99 (7%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
PA G TLQ L LS L +I L L L+L++N ++ LP + +L L L
Sbjct: 188 PALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVL 247
Query: 202 ANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP 240
+N L D L P +T+ LDL N+L LP
Sbjct: 248 HSNLL-ASVPADLARL--PLLTR----LDLRDNQLRDLP 279
>AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein.
Length = 910
Score = 65.3 bits (152), Expect = 4e-10
Identities = 52/144 (36%), Positives = 70/144 (48%), Gaps = 8/144 (5%)
Query: 160 LCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLG 219
L N + L HLA LDLS N +E LP +M L L L++N L + LG
Sbjct: 114 LTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLS-----ELPEALG 168
Query: 220 PQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
L L +T N+L LP A+ L L L + N++ LP IG + +L ++S
Sbjct: 169 A--LPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLAS 226
Query: 280 NELQSLPCSLMQCR-LEYIDISSN 302
N LQSLP SL R L + + SN
Sbjct: 227 NRLQSLPASLAGLRSLRLLVLHSN 250
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 11/145 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L +L LS L + L L L +++N ++ LPP G ++ L L L+ N L
Sbjct: 148 RGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLD 207
Query: 208 VRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 265
L P+I +L L+L SN+L LP ++ L L L + N+++ +PA
Sbjct: 208 T---------LPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPAD 258
Query: 266 IGRISTLRYFTISSNELQSLPCSLM 290
+ R+ L + N+L+ LP L+
Sbjct: 259 LARLPLLTRLDLRDNQLRDLPPELL 283
Score = 56.0 bits (129), Expect = 2e-07
Identities = 43/138 (31%), Positives = 68/138 (49%), Gaps = 8/138 (5%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L ++ L L LS+N + +LP G + L+ L + +N+L LG TL
Sbjct: 144 VLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPA-----LGA--LSTL 196
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+ LDL+ N L LP I L L+ L N + LPA++ + +LR + SN L S+P
Sbjct: 197 QRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVP 256
Query: 287 CSLMQC-RLEYIDISSNK 303
L + L +D+ N+
Sbjct: 257 ADLARLPLLTRLDLRDNQ 274
Score = 31.5 bits (68), Expect = 5.6
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 7/99 (7%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
PA G TLQ L LS L +I L L L+L++N ++ LP + +L L L
Sbjct: 188 PALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVL 247
Query: 202 ANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP 240
+N L D L P +T+ LDL N+L LP
Sbjct: 248 HSNLL-ASVPADLARL--PLLTR----LDLRDNQLRDLP 279
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 64.9 bits (151), Expect = 5e-10
Identities = 48/158 (30%), Positives = 86/158 (54%), Gaps = 12/158 (7%)
Query: 150 LQSLYLSGLKLC--NFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
LQ+L+L + N + L +LA +DLS N++ ++P + +L L+L++NQ+
Sbjct: 200 LQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIT 259
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS--RLPAT 265
+ +W+ ++ L+L+ N+L LP AI KL KL L N N + LP+
Sbjct: 260 ELSLCIDQWV-------HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSG 312
Query: 266 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
IG+++ L F ++N L+ +P SL +C +L + ++ N
Sbjct: 313 IGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKN 350
Score = 52.0 bits (119), Expect = 4e-06
Identities = 45/156 (28%), Positives = 72/156 (46%), Gaps = 20/156 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN--------QLGVRGVVDWRWLLGPQ 221
L L LDLS N +E LPP+ R+ +L L L N QL + L Q
Sbjct: 150 LTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQ 209
Query: 222 ITKT-----------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIS 270
T++ L +DL+ N L +P+ ++ L L L + N I+ L I +
Sbjct: 210 RTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWV 269
Query: 271 TLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKFD 305
+ +S N+L SLP ++ + +L+ + ++SNK D
Sbjct: 270 HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLD 305
Score = 51.2 bits (117), Expect = 6e-06
Identities = 38/139 (27%), Positives = 66/139 (47%), Gaps = 6/139 (4%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L+ L L+ LC ++ L+ L L +S+N + L E + +L + N L
Sbjct: 34 SLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKN 93
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG- 267
GV D + L L +LDL+ N+L P+ + + ++ L + N I +P +
Sbjct: 94 SGVPDDIFKL-----DDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFI 148
Query: 268 RISTLRYFTISSNELQSLP 286
++ L Y +S N L+SLP
Sbjct: 149 NLTDLLYLDLSENRLESLP 167
Score = 46.0 bits (104), Expect = 2e-04
Identities = 46/153 (30%), Positives = 75/153 (49%), Gaps = 14/153 (9%)
Query: 156 SGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWR 215
+ LK DI L L+VLDLS+N++ + P E N+ L+L++N + + +
Sbjct: 89 NSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDT--IPNQL 146
Query: 216 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDN-----MISRLPATIGRIS 270
++ +T L LDL+ N+L LP + +L L TL N N + +LPA + +
Sbjct: 147 FI---NLTDLL-YLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPA-MTALQ 201
Query: 271 TLRYFTISSNELQSLPCSLM-QCRLEYIDISSN 302
TL + + +LP SL L +D+S N
Sbjct: 202 TL-HLRSTQRTQSNLPTSLEGLSNLADVDLSCN 233
Score = 44.0 bits (99), Expect = 0.001
Identities = 41/162 (25%), Positives = 73/162 (45%), Gaps = 8/162 (4%)
Query: 127 NNAPVKLVISDRSQFPA--KGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIE 184
N A V L +D ++ P LP +L+ L LS ++ I H+ L+LS N++
Sbjct: 224 NLADVDLSCNDLTRVPECLYTLP-SLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLT 282
Query: 185 KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW 244
LP +++ L +L+L +N+L G+ G L+ +N L +P+++
Sbjct: 283 SLPSAICKLSKLKKLYLNSNKLDFDGLPS-----GIGKLTNLEEFMAANNNLELVPESLC 337
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+ KL L N N + LP I ++ + + N +P
Sbjct: 338 RCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMP 379
Score = 40.3 bits (90), Expect = 0.012
Identities = 37/136 (27%), Positives = 72/136 (52%), Gaps = 10/136 (7%)
Query: 150 LQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEK--LPPEFGRMANLSELHLANNQL 206
LQ+L L+G L + + R + + L L L + + + LP ++NL+++ L+ N L
Sbjct: 176 LQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDL 235
Query: 207 GVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 266
V + + L +L+ L+L+SN++ L I + + TL + N ++ LP+ I
Sbjct: 236 --TRVPECLYTL-----PSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLPSAI 288
Query: 267 GRISTLRYFTISSNEL 282
++S L+ ++SN+L
Sbjct: 289 CKLSKLKKLYLNSNKL 304
Score = 31.5 bits (68), Expect = 5.6
Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
+L+ L L L +LP+ + L+KL L + N ++ L + + +LR +N L++
Sbjct: 34 SLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKN 93
Query: 285 --LPCSLMQC-RLEYIDISSNK 303
+P + + L +D+S N+
Sbjct: 94 SGVPDDIFKLDDLSVLDLSHNQ 115
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog
protein.
Length = 1268
Score = 64.9 bits (151), Expect = 5e-10
Identities = 48/158 (30%), Positives = 86/158 (54%), Gaps = 12/158 (7%)
Query: 150 LQSLYLSGLKLC--NFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
LQ+L+L + N + L +LA +DLS N++ ++P + +L L+L++NQ+
Sbjct: 199 LQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIT 258
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS--RLPAT 265
+ +W+ ++ L+L+ N+L LP AI KL KL L N N + LP+
Sbjct: 259 ELSLCIDQWV-------HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSG 311
Query: 266 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
IG+++ L F ++N L+ +P SL +C +L + ++ N
Sbjct: 312 IGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKN 349
Score = 52.0 bits (119), Expect = 4e-06
Identities = 45/156 (28%), Positives = 72/156 (46%), Gaps = 20/156 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN--------QLGVRGVVDWRWLLGPQ 221
L L LDLS N +E LPP+ R+ +L L L N QL + L Q
Sbjct: 149 LTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQ 208
Query: 222 ITKT-----------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIS 270
T++ L +DL+ N L +P+ ++ L L L + N I+ L I +
Sbjct: 209 RTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWV 268
Query: 271 TLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKFD 305
+ +S N+L SLP ++ + +L+ + ++SNK D
Sbjct: 269 HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLD 304
Score = 51.2 bits (117), Expect = 6e-06
Identities = 38/139 (27%), Positives = 66/139 (47%), Gaps = 6/139 (4%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L+ L L+ LC ++ L+ L L +S+N + L E + +L + N L
Sbjct: 33 SLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKN 92
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG- 267
GV D + L L +LDL+ N+L P+ + + ++ L + N I +P +
Sbjct: 93 SGVPDDIFKL-----DDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFI 147
Query: 268 RISTLRYFTISSNELQSLP 286
++ L Y +S N L+SLP
Sbjct: 148 NLTDLLYLDLSENRLESLP 166
Score = 46.0 bits (104), Expect = 2e-04
Identities = 46/153 (30%), Positives = 75/153 (49%), Gaps = 14/153 (9%)
Query: 156 SGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWR 215
+ LK DI L L+VLDLS+N++ + P E N+ L+L++N + + +
Sbjct: 88 NSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDT--IPNQL 145
Query: 216 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDN-----MISRLPATIGRIS 270
++ +T L LDL+ N+L LP + +L L TL N N + +LPA + +
Sbjct: 146 FI---NLTDLL-YLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPA-MTALQ 200
Query: 271 TLRYFTISSNELQSLPCSLM-QCRLEYIDISSN 302
TL + + +LP SL L +D+S N
Sbjct: 201 TL-HLRSTQRTQSNLPTSLEGLSNLADVDLSCN 232
Score = 44.0 bits (99), Expect = 0.001
Identities = 41/162 (25%), Positives = 73/162 (45%), Gaps = 8/162 (4%)
Query: 127 NNAPVKLVISDRSQFPA--KGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIE 184
N A V L +D ++ P LP +L+ L LS ++ I H+ L+LS N++
Sbjct: 223 NLADVDLSCNDLTRVPECLYTLP-SLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLT 281
Query: 185 KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW 244
LP +++ L +L+L +N+L G+ G L+ +N L +P+++
Sbjct: 282 SLPSAICKLSKLKKLYLNSNKLDFDGLPS-----GIGKLTNLEEFMAANNNLELVPESLC 336
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+ KL L N N + LP I ++ + + N +P
Sbjct: 337 RCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMP 378
Score = 40.3 bits (90), Expect = 0.012
Identities = 37/136 (27%), Positives = 72/136 (52%), Gaps = 10/136 (7%)
Query: 150 LQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEK--LPPEFGRMANLSELHLANNQL 206
LQ+L L+G L + + R + + L L L + + + LP ++NL+++ L+ N L
Sbjct: 175 LQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDL 234
Query: 207 GVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 266
V + + L +L+ L+L+SN++ L I + + TL + N ++ LP+ I
Sbjct: 235 --TRVPECLYTL-----PSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLPSAI 287
Query: 267 GRISTLRYFTISSNEL 282
++S L+ ++SN+L
Sbjct: 288 CKLSKLKKLYLNSNKL 303
Score = 31.5 bits (68), Expect = 5.6
Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
+L+ L L L +LP+ + L+KL L + N ++ L + + +LR +N L++
Sbjct: 33 SLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKN 92
Query: 285 --LPCSLMQC-RLEYIDISSNK 303
+P + + L +D+S N+
Sbjct: 93 SGVPDDIFKLDDLSVLDLSHNQ 114
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 64.9 bits (151), Expect = 5e-10
Identities = 48/158 (30%), Positives = 86/158 (54%), Gaps = 12/158 (7%)
Query: 150 LQSLYLSGLKLC--NFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
LQ+L+L + N + L +LA +DLS N++ ++P + +L L+L++NQ+
Sbjct: 200 LQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIT 259
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS--RLPAT 265
+ +W+ ++ L+L+ N+L LP AI KL KL L N N + LP+
Sbjct: 260 ELSLCIDQWV-------HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSG 312
Query: 266 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
IG+++ L F ++N L+ +P SL +C +L + ++ N
Sbjct: 313 IGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKN 350
Score = 52.0 bits (119), Expect = 4e-06
Identities = 45/156 (28%), Positives = 72/156 (46%), Gaps = 20/156 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN--------QLGVRGVVDWRWLLGPQ 221
L L LDLS N +E LPP+ R+ +L L L N QL + L Q
Sbjct: 150 LTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQ 209
Query: 222 ITKT-----------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIS 270
T++ L +DL+ N L +P+ ++ L L L + N I+ L I +
Sbjct: 210 RTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWV 269
Query: 271 TLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKFD 305
+ +S N+L SLP ++ + +L+ + ++SNK D
Sbjct: 270 HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLD 305
Score = 51.2 bits (117), Expect = 6e-06
Identities = 38/139 (27%), Positives = 66/139 (47%), Gaps = 6/139 (4%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L+ L L+ LC ++ L+ L L +S+N + L E + +L + N L
Sbjct: 34 SLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKN 93
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG- 267
GV D + L L +LDL+ N+L P+ + + ++ L + N I +P +
Sbjct: 94 SGVPDDIFKL-----DDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFI 148
Query: 268 RISTLRYFTISSNELQSLP 286
++ L Y +S N L+SLP
Sbjct: 149 NLTDLLYLDLSENRLESLP 167
Score = 46.0 bits (104), Expect = 2e-04
Identities = 46/153 (30%), Positives = 75/153 (49%), Gaps = 14/153 (9%)
Query: 156 SGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWR 215
+ LK DI L L+VLDLS+N++ + P E N+ L+L++N + + +
Sbjct: 89 NSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDT--IPNQL 146
Query: 216 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDN-----MISRLPATIGRIS 270
++ +T L LDL+ N+L LP + +L L TL N N + +LPA + +
Sbjct: 147 FI---NLTDLL-YLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPA-MTALQ 201
Query: 271 TLRYFTISSNELQSLPCSLM-QCRLEYIDISSN 302
TL + + +LP SL L +D+S N
Sbjct: 202 TL-HLRSTQRTQSNLPTSLEGLSNLADVDLSCN 233
Score = 44.0 bits (99), Expect = 0.001
Identities = 41/162 (25%), Positives = 73/162 (45%), Gaps = 8/162 (4%)
Query: 127 NNAPVKLVISDRSQFPA--KGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIE 184
N A V L +D ++ P LP +L+ L LS ++ I H+ L+LS N++
Sbjct: 224 NLADVDLSCNDLTRVPECLYTLP-SLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLT 282
Query: 185 KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW 244
LP +++ L +L+L +N+L G+ G L+ +N L +P+++
Sbjct: 283 SLPSAICKLSKLKKLYLNSNKLDFDGLPS-----GIGKLTNLEEFMAANNNLELVPESLC 337
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+ KL L N N + LP I ++ + + N +P
Sbjct: 338 RCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMP 379
Score = 40.3 bits (90), Expect = 0.012
Identities = 37/136 (27%), Positives = 72/136 (52%), Gaps = 10/136 (7%)
Query: 150 LQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEK--LPPEFGRMANLSELHLANNQL 206
LQ+L L+G L + + R + + L L L + + + LP ++NL+++ L+ N L
Sbjct: 176 LQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDL 235
Query: 207 GVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 266
V + + L +L+ L+L+SN++ L I + + TL + N ++ LP+ I
Sbjct: 236 --TRVPECLYTL-----PSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLPSAI 288
Query: 267 GRISTLRYFTISSNEL 282
++S L+ ++SN+L
Sbjct: 289 CKLSKLKKLYLNSNKL 304
Score = 31.5 bits (68), Expect = 5.6
Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
+L+ L L L +LP+ + L+KL L + N ++ L + + +LR +N L++
Sbjct: 34 SLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKN 93
Query: 285 --LPCSLMQC-RLEYIDISSNK 303
+P + + L +D+S N+
Sbjct: 94 SGVPDDIFKLDDLSVLDLSHNQ 115
>AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat
containing 5 variant protein.
Length = 671
Score = 64.9 bits (151), Expect = 5e-10
Identities = 46/147 (31%), Positives = 72/147 (48%), Gaps = 7/147 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L L L K+ I +K+L L SNN++E LP + L L ++ N +
Sbjct: 496 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 555
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + +G + + L+ L +T NK+ LPK ++K KL TL N I+ LP +G
Sbjct: 556 MIPIE-----IG--LLQDLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVG 608
Query: 268 RISTLRYFTISSNELQSLPCSLMQCRL 294
++S L + N L LP L QCR+
Sbjct: 609 QLSQLTQLELKGNCLDRLPAQLGQCRM 635
Score = 64.5 bits (150), Expect = 6e-10
Identities = 45/156 (28%), Positives = 78/156 (50%), Gaps = 13/156 (8%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L+SLY S KL + + L+ L LD+S N I +P E G + +L LH+ N++
Sbjct: 519 KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQDLQHLHITGNKVD 578
Query: 208 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 265
+ L Q+ K +KL L+L N + LP+ + +L +L L+ N + RLPA
Sbjct: 579 I---------LPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQ 629
Query: 266 IGRISTLRY--FTISSNELQSLPCSLMQCRLEYIDI 299
+G+ L+ + + +LP + + + I+I
Sbjct: 630 LGQCRMLKKSGLVVEDHLFDTLPLEVEEALNQDINI 665
Score = 60.9 bits (141), Expect = 8e-09
Identities = 38/137 (27%), Positives = 73/137 (53%), Gaps = 6/137 (4%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
+ ++A L+L N E+E++P ++NL EL L +N +R + + ++ Q K L L
Sbjct: 447 MMNVAELELQNCELERIPHAIFSLSNLQELDLKSNN--IRTIEE---IISFQHLKRLTCL 501
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
L NK+ +P +I ++ L +L ++N + LP + + LR +S N + +P +
Sbjct: 502 KLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEI 561
Query: 290 -MQCRLEYIDISSNKFD 305
+ L+++ I+ NK D
Sbjct: 562 GLLQDLQHLHITGNKVD 578
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 64.9 bits (151), Expect = 5e-10
Identities = 48/158 (30%), Positives = 86/158 (54%), Gaps = 12/158 (7%)
Query: 150 LQSLYLSGLKLC--NFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
LQ+L+L + N + L +LA +DLS N++ ++P + +L L+L++NQ+
Sbjct: 187 LQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIT 246
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS--RLPAT 265
+ +W+ ++ L+L+ N+L LP AI KL KL L N N + LP+
Sbjct: 247 ELSLCIDQWV-------HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSG 299
Query: 266 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
IG+++ L F ++N L+ +P SL +C +L + ++ N
Sbjct: 300 IGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKN 337
Score = 52.0 bits (119), Expect = 4e-06
Identities = 45/156 (28%), Positives = 72/156 (46%), Gaps = 20/156 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN--------QLGVRGVVDWRWLLGPQ 221
L L LDLS N +E LPP+ R+ +L L L N QL + L Q
Sbjct: 137 LTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQ 196
Query: 222 ITKT-----------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIS 270
T++ L +DL+ N L +P+ ++ L L L + N I+ L I +
Sbjct: 197 RTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWV 256
Query: 271 TLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKFD 305
+ +S N+L SLP ++ + +L+ + ++SNK D
Sbjct: 257 HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLD 292
Score = 51.2 bits (117), Expect = 6e-06
Identities = 38/139 (27%), Positives = 66/139 (47%), Gaps = 6/139 (4%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L+ L L+ LC ++ L+ L L +S+N + L E + +L + N L
Sbjct: 21 SLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKN 80
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG- 267
GV D + L L +LDL+ N+L P+ + + ++ L + N I +P +
Sbjct: 81 SGVPDDIFKL-----DDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFI 135
Query: 268 RISTLRYFTISSNELQSLP 286
++ L Y +S N L+SLP
Sbjct: 136 NLTDLLYLDLSENRLESLP 154
Score = 46.0 bits (104), Expect = 2e-04
Identities = 46/153 (30%), Positives = 75/153 (49%), Gaps = 14/153 (9%)
Query: 156 SGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWR 215
+ LK DI L L+VLDLS+N++ + P E N+ L+L++N + + +
Sbjct: 76 NSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDT--IPNQL 133
Query: 216 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDN-----MISRLPATIGRIS 270
++ +T L LDL+ N+L LP + +L L TL N N + +LPA + +
Sbjct: 134 FI---NLTDLL-YLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPA-MTALQ 188
Query: 271 TLRYFTISSNELQSLPCSLM-QCRLEYIDISSN 302
TL + + +LP SL L +D+S N
Sbjct: 189 TL-HLRSTQRTQSNLPTSLEGLSNLADVDLSCN 220
Score = 44.0 bits (99), Expect = 0.001
Identities = 41/162 (25%), Positives = 73/162 (45%), Gaps = 8/162 (4%)
Query: 127 NNAPVKLVISDRSQFPA--KGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIE 184
N A V L +D ++ P LP +L+ L LS ++ I H+ L+LS N++
Sbjct: 211 NLADVDLSCNDLTRVPECLYTLP-SLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLT 269
Query: 185 KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW 244
LP +++ L +L+L +N+L G+ G L+ +N L +P+++
Sbjct: 270 SLPSAICKLSKLKKLYLNSNKLDFDGLPS-----GIGKLTNLEEFMAANNNLELVPESLC 324
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+ KL L N N + LP I ++ + + N +P
Sbjct: 325 RCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMP 366
Score = 40.3 bits (90), Expect = 0.012
Identities = 37/136 (27%), Positives = 72/136 (52%), Gaps = 10/136 (7%)
Query: 150 LQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEK--LPPEFGRMANLSELHLANNQL 206
LQ+L L+G L + + R + + L L L + + + LP ++NL+++ L+ N L
Sbjct: 163 LQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDL 222
Query: 207 GVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 266
V + + L +L+ L+L+SN++ L I + + TL + N ++ LP+ I
Sbjct: 223 --TRVPECLYTL-----PSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLPSAI 275
Query: 267 GRISTLRYFTISSNEL 282
++S L+ ++SN+L
Sbjct: 276 CKLSKLKKLYLNSNKL 291
Score = 31.5 bits (68), Expect = 5.6
Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
+L+ L L L +LP+ + L+KL L + N ++ L + + +LR +N L++
Sbjct: 21 SLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKN 80
Query: 285 --LPCSLMQC-RLEYIDISSNK 303
+P + + L +D+S N+
Sbjct: 81 SGVPDDIFKLDDLSVLDLSHNQ 102
>BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat
containing 28 protein.
Length = 367
Score = 64.5 bits (150), Expect = 6e-10
Identities = 51/163 (31%), Positives = 83/163 (50%), Gaps = 13/163 (7%)
Query: 143 AKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLA 202
A+ LP ++ LYL + I L L LDLS+N +E + PE GR+ L L LA
Sbjct: 61 AQKLPNLVE-LYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLA 119
Query: 203 NNQLGVRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS 260
NNQL L P++ K L+ LD+++N+L LP+ + L L + N +
Sbjct: 120 NNQL---------QFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLW 170
Query: 261 RLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
+P + ++ +L +++ N L LP L + R L+Y+ + +N
Sbjct: 171 YVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNN 213
Score = 48.8 bits (111), Expect = 3e-05
Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L L SN + +P+AI L KL L +DN + + IGR+ LR+ +++N+LQ LP
Sbjct: 70 LYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPE 129
Query: 289 LMQCR-LEYIDISSNK 303
+ + L+ +DIS+N+
Sbjct: 130 VGDLKELQTLDISTNR 145
Score = 30.7 bits (66), Expect = 9.8
Identities = 31/126 (24%), Positives = 56/126 (44%), Gaps = 12/126 (9%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
P G R L+ L L+ +L ++ LK L LD+S N + LP +L L +
Sbjct: 105 PEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTV 164
Query: 202 ANNQLGVRGVVDWRWLLGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM- 258
N+L W + + + +L L + N+L LP + + +L + ++N+
Sbjct: 165 DRNRL---------WYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNNIH 215
Query: 259 ISRLPA 264
+ LP+
Sbjct: 216 LKGLPS 221
>AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein.
Length = 312
Score = 64.5 bits (150), Expect = 6e-10
Identities = 51/163 (31%), Positives = 83/163 (50%), Gaps = 13/163 (7%)
Query: 143 AKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLA 202
A+ LP ++ LYL + I L L LDLS+N +E + PE GR+ L L LA
Sbjct: 61 AQKLPNLVE-LYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLA 119
Query: 203 NNQLGVRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS 260
NNQL L P++ K L+ LD+++N+L LP+ + L L + N +
Sbjct: 120 NNQL---------QFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLW 170
Query: 261 RLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
+P + ++ +L +++ N L LP L + R L+Y+ + +N
Sbjct: 171 YVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNN 213
Score = 48.8 bits (111), Expect = 3e-05
Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L L SN + +P+AI L KL L +DN + + IGR+ LR+ +++N+LQ LP
Sbjct: 70 LYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPE 129
Query: 289 LMQCR-LEYIDISSNK 303
+ + L+ +DIS+N+
Sbjct: 130 VGDLKELQTLDISTNR 145
Score = 30.7 bits (66), Expect = 9.8
Identities = 31/126 (24%), Positives = 56/126 (44%), Gaps = 12/126 (9%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
P G R L+ L L+ +L ++ LK L LD+S N + LP +L L +
Sbjct: 105 PEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTV 164
Query: 202 ANNQLGVRGVVDWRWLLGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM- 258
N+L W + + + +L L + N+L LP + + +L + ++N+
Sbjct: 165 DRNRL---------WYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNNIH 215
Query: 259 ISRLPA 264
+ LP+
Sbjct: 216 LKGLPS 221
>AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar to
Ras suppressor protein 1r 4 (tax-transcriptionally act
protein.
Length = 146
Score = 64.5 bits (150), Expect = 6e-10
Identities = 47/141 (33%), Positives = 72/141 (51%), Gaps = 10/141 (7%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
+I LK+L VL+ NN+IEKLP + R+ L L+L N+L + G
Sbjct: 4 NIAELKNLEVLNFLNNQIEKLPTQISRLQKLKHLNLGMNRLNISP-------QGFGSLPA 56
Query: 226 LKLLDLTSNKL--GHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
L++LDLT N L +LP + L L L +DN LP IG+++ L+ + N L
Sbjct: 57 LEVLDLTYNNLNENYLPGNFFYLTTLCALYLSDNDFEILPPDIGKLTKLQILSNRDNNLI 116
Query: 284 SLPCSL-MQCRLEYIDISSNK 303
SLP + + +L+ + I N+
Sbjct: 117 SLPKEIRVLTQLKELHIQGNR 137
Score = 34.3 bits (75), Expect = 0.79
Identities = 22/60 (36%), Positives = 29/60 (48%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
TL +LYLS DI L L +L +N + LP E + L ELH+ N+L V
Sbjct: 81 TLCALYLSDNDFEILPPDIGKLTKLQILSNRDNNLISLPKEIRVLTQLKELHIQGNRLTV 140
>L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein.
Length = 277
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 10/157 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 267
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 303
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 14/141 (9%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 224
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 282
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 283 QSLPCSLMQ-CRLEYIDISSN 302
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
TL++LYLS DI L L +L L +N++ LP E G + L ELH+ N+L V
Sbjct: 135 TLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
>CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 10/157 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 267
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 303
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 14/141 (9%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 224
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 282
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 283 QSLPCSLMQ-CRLEYIDISSN 302
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
TL++LYLS DI L L +L L +N++ LP E G + L ELH+ N+L V
Sbjct: 135 TLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
>CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 10/157 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 267
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 303
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 14/141 (9%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 224
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 282
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 283 QSLPCSLMQ-CRLEYIDISSN 302
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
TL++LYLS DI L L +L L +N++ LP E G + L ELH+ N+L V
Sbjct: 135 TLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
>BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein.
Length = 280
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 10/157 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 45 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 104
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 267
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 105 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 157
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 303
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 158 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 194
Score = 52.4 bits (120), Expect = 3e-06
Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 14/138 (10%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--KTLK 227
L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ + LK
Sbjct: 42 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQKLK 92
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNELQSL 285
L+L N+L LP+ L L L N +S LP ++TLR +S N+ + L
Sbjct: 93 HLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEIL 152
Query: 286 PCSLMQ-CRLEYIDISSN 302
P + + +L+ + + N
Sbjct: 153 PPDIGKLTKLQILSLRDN 170
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
TL++LYLS DI L L +L L +N++ LP E G + L ELH+ N+L V
Sbjct: 138 TLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 197
>BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein.
Length = 250
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 14/153 (9%)
Query: 155 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 214
LSG +L F + + L L LS+N + LPPE G++ NL L L N
Sbjct: 9 LSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKAL----- 63
Query: 215 RWLLGPQITKTLK---LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
PQ+ TLK +L L +NKL LP + L+ L TL N +++LP + +S
Sbjct: 64 -----PQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSL 118
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
L+ SN L+ LP L + + L I +S N+
Sbjct: 119 LKTLHAGSNALRLLPGQLRRLQELRTIWLSGNR 151
Score = 59.3 bits (137), Expect = 2e-08
Identities = 49/156 (31%), Positives = 72/156 (46%), Gaps = 8/156 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L LYLS L + ++ L++L +L L N + LP + L L+L NN+L
Sbjct: 25 RELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKL- 83
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
D L + + L+ L + +N L LP + +L L TL A N + LP +
Sbjct: 84 ----CDLPSELS--LLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 137
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
R+ LR +S N L P L+ LE ID+ N
Sbjct: 138 RLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWN 173
Score = 45.2 bits (102), Expect = 4e-04
Identities = 44/159 (27%), Positives = 68/159 (42%), Gaps = 10/159 (6%)
Query: 131 VKLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFR---RDILLLKHLAVLDLSNNEIEKLP 187
VKL +SD LQ+L + L NF+ + + LK L +L L NN++ LP
Sbjct: 28 VKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLP 87
Query: 188 PEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLE 247
E + NL L + N L V L LK L SN L LP + +L+
Sbjct: 88 SELSLLQNLRTLWIEANCLTQLPDVVCELSL-------LKTLHAGSNALRLLPGQLRRLQ 140
Query: 248 KLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+L T+ + N ++ P + + L + N ++ P
Sbjct: 141 ELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFP 179
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
K++DL+ ++L P + +LV L +DN ++ LP +G++ L+ + N ++LP
Sbjct: 5 KMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALP 64
Query: 287 ---CSLMQCRLEYI 297
C+L Q + Y+
Sbjct: 65 QVVCTLKQLCILYL 78
>BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein.
Length = 249
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 14/153 (9%)
Query: 155 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 214
LSG +L F + + L L LS+N + LPPE G++ NL L L N
Sbjct: 8 LSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKAL----- 62
Query: 215 RWLLGPQITKTLK---LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
PQ+ TLK +L L +NKL LP + L+ L TL N +++LP + +S
Sbjct: 63 -----PQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSL 117
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
L+ SN L+ LP L + + L I +S N+
Sbjct: 118 LKTLHAGSNALRLLPGQLRRLQELRTIWLSGNR 150
Score = 59.3 bits (137), Expect = 2e-08
Identities = 49/156 (31%), Positives = 72/156 (46%), Gaps = 8/156 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L LYLS L + ++ L++L +L L N + LP + L L+L NN+L
Sbjct: 24 RELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKL- 82
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
D L + + L+ L + +N L LP + +L L TL A N + LP +
Sbjct: 83 ----CDLPSELS--LLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 136
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
R+ LR +S N L P L+ LE ID+ N
Sbjct: 137 RLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWN 172
Score = 45.2 bits (102), Expect = 4e-04
Identities = 44/159 (27%), Positives = 68/159 (42%), Gaps = 10/159 (6%)
Query: 131 VKLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFR---RDILLLKHLAVLDLSNNEIEKLP 187
VKL +SD LQ+L + L NF+ + + LK L +L L NN++ LP
Sbjct: 27 VKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLP 86
Query: 188 PEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLE 247
E + NL L + N L V L LK L SN L LP + +L+
Sbjct: 87 SELSLLQNLRTLWIEANCLTQLPDVVCELSL-------LKTLHAGSNALRLLPGQLRRLQ 139
Query: 248 KLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+L T+ + N ++ P + + L + N ++ P
Sbjct: 140 ELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFP 178
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
K++DL+ ++L P + +LV L +DN ++ LP +G++ L+ + N ++LP
Sbjct: 4 KMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALP 63
Query: 287 ---CSLMQCRLEYI 297
C+L Q + Y+
Sbjct: 64 QVVCTLKQLCILYL 77
>BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat
containing 10 protein.
Length = 277
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 14/153 (9%)
Query: 155 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 214
LSG +L F + + L L LS+N + LPPE G++ NL L L N
Sbjct: 36 LSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKAL----- 90
Query: 215 RWLLGPQITKTLK---LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
PQ+ TLK +L L +NKL LP + L+ L TL N +++LP + +S
Sbjct: 91 -----PQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSL 145
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
L+ SN L+ LP L + + L I +S N+
Sbjct: 146 LKTLHAGSNALRLLPGQLRRLQELRTIWLSGNR 178
Score = 59.3 bits (137), Expect = 2e-08
Identities = 49/156 (31%), Positives = 72/156 (46%), Gaps = 8/156 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L LYLS L + ++ L++L +L L N + LP + L L+L NN+L
Sbjct: 52 RELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKL- 110
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
D L + + L+ L + +N L LP + +L L TL A N + LP +
Sbjct: 111 ----CDLPSELS--LLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 164
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
R+ LR +S N L P L+ LE ID+ N
Sbjct: 165 RLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWN 200
Score = 45.2 bits (102), Expect = 4e-04
Identities = 44/159 (27%), Positives = 68/159 (42%), Gaps = 10/159 (6%)
Query: 131 VKLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFR---RDILLLKHLAVLDLSNNEIEKLP 187
VKL +SD LQ+L + L NF+ + + LK L +L L NN++ LP
Sbjct: 55 VKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLP 114
Query: 188 PEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLE 247
E + NL L + N L V L LK L SN L LP + +L+
Sbjct: 115 SELSLLQNLRTLWIEANCLTQLPDVVCELSL-------LKTLHAGSNALRLLPGQLRRLQ 167
Query: 248 KLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+L T+ + N ++ P + + L + N ++ P
Sbjct: 168 ELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFP 206
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
K++DL+ ++L P + +LV L +DN ++ LP +G++ L+ + N ++LP
Sbjct: 32 KMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALP 91
Query: 287 ---CSLMQCRLEYI 297
C+L Q + Y+
Sbjct: 92 QVVCTLKQLCILYL 105
>BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 10/157 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 267
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 303
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 14/141 (9%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 224
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 282
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 283 QSLPCSLMQ-CRLEYIDISSN 302
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
TL++LYLS DI L L +L L +N++ LP E G + L ELH+ N+L V
Sbjct: 135 TLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
>BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 335
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/163 (31%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLS-NNEIEKLPPEFGRMANLSELH 200
P GL LQ L LS K+ +++ L L+L+ N +I LP E + L+ L
Sbjct: 123 PGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLD 182
Query: 201 LANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS 260
L+ N + L P L+ LD+ SNKL LP I +++ L TL N I+
Sbjct: 183 LSMNDFTT---IPLAVLNMP----ALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEIT 235
Query: 261 RLPATIGRISTLRYFTISSNELQSLP-CSLMQCRLEYIDISSN 302
LP TI + L +S+N+LQ +P C L +++ N
Sbjct: 236 CLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
Score = 52.8 bits (121), Expect = 2e-06
Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 18/154 (11%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV--RGVVDWRWL----------- 217
++L VLDLS N I ++PP G + L EL L+ N++ + + + L
Sbjct: 106 QNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDI 165
Query: 218 --LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L +++ LKL LDL+ N +P A+ + L L N + +LP TI R+ L
Sbjct: 166 CDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLH 225
Query: 274 YFTISSNELQSLPCSLMQCR-LEYIDISSNKFDN 306
+ NE+ LP ++ + L + +S+NK +
Sbjct: 226 TLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQD 259
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 9/141 (6%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L L L L + K+P GR NL L L+ N + G + L
Sbjct: 79 LLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTIS-------EIPPGIGLLTRL 131
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLK-ANDNMISRLPATIGRISTLRYFTISSNELQSL 285
+ L L+ NK+ +PK + L L+ A + I LP + + L + +S N+ ++
Sbjct: 132 QELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTI 191
Query: 286 PCSLMQC-RLEYIDISSNKFD 305
P +++ LE++D+ SNK +
Sbjct: 192 PLAVLNMPALEWLDMGSNKLE 212
Score = 33.1 bits (72), Expect = 1.8
Identities = 18/62 (29%), Positives = 35/62 (56%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L +L+L ++ + I +K+L L LSNN+++ +P MANL ++ +N L
Sbjct: 222 QNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Query: 208 VR 209
++
Sbjct: 282 LK 283
Score = 32.7 bits (71), Expect = 2.4
Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+L + + LP ++ KL +L + + + ++P IGR L +S N + +P
Sbjct: 64 ILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPP 123
Query: 288 SL-MQCRLEYIDISSNK 303
+ + RL+ + +S NK
Sbjct: 124 GIGLLTRLQELILSYNK 140
>BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein.
Length = 277
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 10/157 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 267
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 303
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 14/141 (9%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 224
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 282
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 283 QSLPCSLMQ-CRLEYIDISSN 302
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
TL++LYLS DI L L +L L +N++ LP E G + L ELH+ N+L V
Sbjct: 135 TLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
>BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 10/157 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 267
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 303
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 14/141 (9%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 224
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 282
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 283 QSLPCSLMQ-CRLEYIDISSN 302
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
TL++LYLS DI L L +L L +N++ LP E G + L ELH+ N+L V
Sbjct: 135 TLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
>AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein.
Length = 335
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/163 (31%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLS-NNEIEKLPPEFGRMANLSELH 200
P GL LQ L LS K+ +++ L L+L+ N +I LP E + L+ L
Sbjct: 123 PGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLD 182
Query: 201 LANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS 260
L+ N + L P L+ LD+ SNKL LP I +++ L TL N I+
Sbjct: 183 LSMNDFTT---IPLAVLNMP----ALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEIT 235
Query: 261 RLPATIGRISTLRYFTISSNELQSLP-CSLMQCRLEYIDISSN 302
LP TI + L +S+N+LQ +P C L +++ N
Sbjct: 236 CLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
Score = 52.8 bits (121), Expect = 2e-06
Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 18/154 (11%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV--RGVVDWRWL----------- 217
++L VLDLS N I ++PP G + L EL L+ N++ + + + L
Sbjct: 106 QNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDI 165
Query: 218 --LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L +++ LKL LDL+ N +P A+ + L L N + +LP TI R+ L
Sbjct: 166 CDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLH 225
Query: 274 YFTISSNELQSLPCSLMQCR-LEYIDISSNKFDN 306
+ NE+ LP ++ + L + +S+NK +
Sbjct: 226 TLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQD 259
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 9/141 (6%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L L L L + K+P GR NL L L+ N + G + L
Sbjct: 79 LLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTIS-------EIPPGIGLLTRL 131
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLK-ANDNMISRLPATIGRISTLRYFTISSNELQSL 285
+ L L+ NK+ +PK + L L+ A + I LP + + L + +S N+ ++
Sbjct: 132 QELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTI 191
Query: 286 PCSLMQC-RLEYIDISSNKFD 305
P +++ LE++D+ SNK +
Sbjct: 192 PLAVLNMPALEWLDMGSNKLE 212
Score = 33.1 bits (72), Expect = 1.8
Identities = 18/62 (29%), Positives = 35/62 (56%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L +L+L ++ + I +K+L L LSNN+++ +P MANL ++ +N L
Sbjct: 222 QNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Query: 208 VR 209
++
Sbjct: 282 LK 283
Score = 32.7 bits (71), Expect = 2.4
Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+L + + LP ++ KL +L + + + ++P IGR L +S N + +P
Sbjct: 64 ILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPP 123
Query: 288 SL-MQCRLEYIDISSNK 303
+ + RL+ + +S NK
Sbjct: 124 GIGLLTRLQELILSYNK 140
>AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 339
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/163 (31%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLS-NNEIEKLPPEFGRMANLSELH 200
P GL LQ L LS K+ +++ L L+L+ N +I LP E + L+ L
Sbjct: 123 PGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLD 182
Query: 201 LANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS 260
L+ N + L P L+ LD+ SNKL LP I +++ L TL N I+
Sbjct: 183 LSMNDFTT---IPLAVLNMP----ALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEIT 235
Query: 261 RLPATIGRISTLRYFTISSNELQSLP-CSLMQCRLEYIDISSN 302
LP TI + L +S+N+LQ +P C L +++ N
Sbjct: 236 CLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
Score = 52.8 bits (121), Expect = 2e-06
Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 18/154 (11%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV--RGVVDWRWL----------- 217
++L VLDLS N I ++PP G + L EL L+ N++ + + + L
Sbjct: 106 QNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDI 165
Query: 218 --LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L +++ LKL LDL+ N +P A+ + L L N + +LP TI R+ L
Sbjct: 166 CDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLH 225
Query: 274 YFTISSNELQSLPCSLMQCR-LEYIDISSNKFDN 306
+ NE+ LP ++ + L + +S+NK +
Sbjct: 226 TLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQD 259
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 9/141 (6%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L L L L + K+P GR NL L L+ N + G + L
Sbjct: 79 LLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTIS-------EIPPGIGLLTRL 131
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLK-ANDNMISRLPATIGRISTLRYFTISSNELQSL 285
+ L L+ NK+ +PK + L L+ A + I LP + + L + +S N+ ++
Sbjct: 132 QELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTI 191
Query: 286 PCSLMQC-RLEYIDISSNKFD 305
P +++ LE++D+ SNK +
Sbjct: 192 PLAVLNMPALEWLDMGSNKLE 212
Score = 33.1 bits (72), Expect = 1.8
Identities = 18/62 (29%), Positives = 35/62 (56%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L +L+L ++ + I +K+L L LSNN+++ +P MANL ++ +N L
Sbjct: 222 QNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Query: 208 VR 209
++
Sbjct: 282 LK 283
Score = 32.7 bits (71), Expect = 2.4
Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+L + + LP ++ KL +L + + + ++P IGR L +S N + +P
Sbjct: 64 ILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPP 123
Query: 288 SL-MQCRLEYIDISSNK 303
+ + RL+ + +S NK
Sbjct: 124 GIGLLTRLQELILSYNK 140
>AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 335
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/163 (31%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLS-NNEIEKLPPEFGRMANLSELH 200
P GL LQ L LS K+ +++ L L+L+ N +I LP E + L+ L
Sbjct: 123 PGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLD 182
Query: 201 LANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS 260
L+ N + L P L+ LD+ SNKL LP I +++ L TL N I+
Sbjct: 183 LSMNDFTT---IPLAVLNMP----ALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEIT 235
Query: 261 RLPATIGRISTLRYFTISSNELQSLP-CSLMQCRLEYIDISSN 302
LP TI + L +S+N+LQ +P C L +++ N
Sbjct: 236 CLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
Score = 52.8 bits (121), Expect = 2e-06
Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 18/154 (11%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV--RGVVDWRWL----------- 217
++L VLDLS N I ++PP G + L EL L+ N++ + + + L
Sbjct: 106 QNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDI 165
Query: 218 --LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
L +++ LKL LDL+ N +P A+ + L L N + +LP TI R+ L
Sbjct: 166 CDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLH 225
Query: 274 YFTISSNELQSLPCSLMQCR-LEYIDISSNKFDN 306
+ NE+ LP ++ + L + +S+NK +
Sbjct: 226 TLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQD 259
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 9/141 (6%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L L L L + K+P GR NL L L+ N + G + L
Sbjct: 79 LLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTIS-------EIPPGIGLLTRL 131
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLK-ANDNMISRLPATIGRISTLRYFTISSNELQSL 285
+ L L+ NK+ +PK + L L+ A + I LP + + L + +S N+ ++
Sbjct: 132 QELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTI 191
Query: 286 PCSLMQC-RLEYIDISSNKFD 305
P +++ LE++D+ SNK +
Sbjct: 192 PLAVLNMPALEWLDMGSNKLE 212
Score = 33.1 bits (72), Expect = 1.8
Identities = 18/62 (29%), Positives = 35/62 (56%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ L +L+L ++ + I +K+L L LSNN+++ +P MANL ++ +N L
Sbjct: 222 QNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Query: 208 VR 209
++
Sbjct: 282 LK 283
Score = 32.7 bits (71), Expect = 2.4
Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+L + + LP ++ KL +L + + + ++P IGR L +S N + +P
Sbjct: 64 ILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPP 123
Query: 288 SL-MQCRLEYIDISSNK 303
+ + RL+ + +S NK
Sbjct: 124 GIGLLTRLQELILSYNK 140
>AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 10/157 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 267
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 268 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 303
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 14/141 (9%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 224
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 282
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 283 QSLPCSLMQ-CRLEYIDISSN 302
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
TL++LYLS DI L L +L L +N++ LP E G + L ELH+ N+L V
Sbjct: 135 TLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
>AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 372
Score = 63.3 bits (147), Expect = 1e-09
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 207
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 193 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 252
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 253 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 304
Query: 268 RISTLRYFTISSN-ELQSLPCSLMQC 292
+ L ++ N L SLP L C
Sbjct: 305 TLENLEELYLNDNPNLHSLPFELALC 330
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 218
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 169 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 228
Query: 219 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 274
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 229 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 288
Query: 275 FTISSNELQSLP 286
+ N L LP
Sbjct: 289 LGLGENLLTHLP 300
Score = 48.0 bits (109), Expect = 6e-05
Identities = 22/66 (33%), Positives = 37/66 (56%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L++LDL NKL +P +++L+ L TL N I+ + I +S L +I N+++
Sbjct: 5 KKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIK 64
Query: 284 SLPCSL 289
LP +
Sbjct: 65 QLPAEI 70
Score = 46.8 bits (106), Expect = 1e-04
Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 14/167 (8%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L +LYL ++ +DI L L++L + N+I++LP E G +++LS L L N+L
Sbjct: 29 SLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGNLSSLSRLGLRYNRLSA 88
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLP-ATI 266
R L L+ L+L +N + LP+++ L KL +L N P
Sbjct: 89 IP----RSLAK---CSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGP 141
Query: 267 GRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTS 313
+ ST+ + N + +P + R + + +K + K N TS
Sbjct: 142 SQFSTIYSLNMEHNRINKIPFGIFS-RAKVL----SKLNMKDNQLTS 183
Score = 42.3 bits (95), Expect = 0.003
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L L++ N+L LP +V L N ++++P + + +L +S+N L+
Sbjct: 169 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 228
Query: 284 SLPCSLMQCR-LEYIDISSNKFDNKQN 309
LP L R L +D+ NK ++ N
Sbjct: 229 KLPHGLGNLRKLRELDLEENKLESLPN 255
Score = 37.9 bits (84), Expect = 0.064
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
+ LQ L L+ +L R I L +L L L N + LP E G + NL EL+L +N
Sbjct: 261 KDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN 317
>AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens
cDNA FLJ41914 fis, clone PERIC2001228. ).
Length = 250
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 14/153 (9%)
Query: 155 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 214
LSG +L F + + L L LS+N + LPPE G++ NL L L N
Sbjct: 9 LSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKAL----- 63
Query: 215 RWLLGPQITKTLK---LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
PQ+ TLK +L L +NKL LP + L+ L TL N +++LP + +S
Sbjct: 64 -----PQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSL 118
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
L+ SN L+ LP L + + L I +S N+
Sbjct: 119 LKTLHAGSNALRLLPGQLRRLQELRTIWLSGNR 151
Score = 59.3 bits (137), Expect = 2e-08
Identities = 49/156 (31%), Positives = 72/156 (46%), Gaps = 8/156 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L LYLS L + ++ L++L +L L N + LP + L L+L NN+L
Sbjct: 25 RELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKL- 83
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
D L + + L+ L + +N L LP + +L L TL A N + LP +
Sbjct: 84 ----CDLPSELS--LLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 137
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
R+ LR +S N L P L+ LE ID+ N
Sbjct: 138 RLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWN 173
Score = 45.2 bits (102), Expect = 4e-04
Identities = 44/159 (27%), Positives = 68/159 (42%), Gaps = 10/159 (6%)
Query: 131 VKLVISDRSQFPAKGLPRTLQSLYLSGLKLCNFR---RDILLLKHLAVLDLSNNEIEKLP 187
VKL +SD LQ+L + L NF+ + + LK L +L L NN++ LP
Sbjct: 28 VKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLP 87
Query: 188 PEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLE 247
E + NL L + N L V L LK L SN L LP + +L+
Sbjct: 88 SELSLLQNLRTLWIEANCLTQLPDVVCELSL-------LKTLHAGSNALRLLPGQLRRLQ 140
Query: 248 KLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+L T+ + N ++ P + + L + N ++ P
Sbjct: 141 ELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFP 179
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
K++DL+ ++L P + +LV L +DN ++ LP +G++ L+ + N ++LP
Sbjct: 5 KMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALP 64
Query: 287 ---CSLMQCRLEYI 297
C+L Q + Y+
Sbjct: 65 QVVCTLKQLCILYL 78
>AL391728-3|CAH73693.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 62.9 bits (146), Expect = 2e-09
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 140
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 141 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 196
Query: 268 RISTLRYFTISSNELQSLP 286
R+ LR + N L++LP
Sbjct: 197 RLVKLRILELRENHLKTLP 215
Score = 49.2 bits (112), Expect = 3e-05
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
+TL+ L L +N++ LPK ++ + L L DN +S LP TI + L+ IS N +Q
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQ 143
Query: 284 SLPCSLMQCR-LEYIDISSN 302
P ++ C+ L I+ S N
Sbjct: 144 EFPENIKCCKCLTIIEASVN 163
Score = 35.5 bits (78), Expect = 0.34
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 173 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 232
L L L N+IE+LP + L +L + +N L + + + LK LD++
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLS-----NLPTTIASLVN--LKELDIS 138
Query: 233 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ- 291
N + P+ I + L ++A+ N IS+LP ++ L ++ L+ LP + +
Sbjct: 139 KNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRL 198
Query: 292 CRLEYIDISSNKFDNKQN 309
+L +++ N N
Sbjct: 199 VKLRILELRENHLKTLPN 216
>AL359894-1|CAH73131.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 62.9 bits (146), Expect = 2e-09
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 140
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 141 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 196
Query: 268 RISTLRYFTISSNELQSLP 286
R+ LR + N L++LP
Sbjct: 197 RLVKLRILELRENHLKTLP 215
Score = 49.2 bits (112), Expect = 3e-05
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
+TL+ L L +N++ LPK ++ + L L DN +S LP TI + L+ IS N +Q
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQ 143
Query: 284 SLPCSLMQCR-LEYIDISSN 302
P ++ C+ L I+ S N
Sbjct: 144 EFPENIKCCKCLTIIEASVN 163
Score = 35.5 bits (78), Expect = 0.34
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 173 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 232
L L L N+IE+LP + L +L + +N L + + + LK LD++
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLS-----NLPTTIASLVN--LKELDIS 138
Query: 233 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ- 291
N + P+ I + L ++A+ N IS+LP ++ L ++ L+ LP + +
Sbjct: 139 KNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRL 198
Query: 292 CRLEYIDISSNKFDNKQN 309
+L +++ N N
Sbjct: 199 VKLRILELRENHLKTLPN 216
>AL359412-3|CAH74020.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 62.9 bits (146), Expect = 2e-09
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 140
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 141 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 196
Query: 268 RISTLRYFTISSNELQSLP 286
R+ LR + N L++LP
Sbjct: 197 RLVKLRILELRENHLKTLP 215
Score = 49.2 bits (112), Expect = 3e-05
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
+TL+ L L +N++ LPK ++ + L L DN +S LP TI + L+ IS N +Q
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQ 143
Query: 284 SLPCSLMQCR-LEYIDISSN 302
P ++ C+ L I+ S N
Sbjct: 144 EFPENIKCCKCLTIIEASVN 163
Score = 35.5 bits (78), Expect = 0.34
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 173 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 232
L L L N+IE+LP + L +L + +N L + + + LK LD++
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLS-----NLPTTIASLVN--LKELDIS 138
Query: 233 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ- 291
N + P+ I + L ++A+ N IS+LP ++ L ++ L+ LP + +
Sbjct: 139 KNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRL 198
Query: 292 CRLEYIDISSNKFDNKQN 309
+L +++ N N
Sbjct: 199 VKLRILELRENHLKTLPN 216
>AL117353-2|CAI23424.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 62.9 bits (146), Expect = 2e-09
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 140
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 141 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 196
Query: 268 RISTLRYFTISSNELQSLP 286
R+ LR + N L++LP
Sbjct: 197 RLVKLRILELRENHLKTLP 215
Score = 49.2 bits (112), Expect = 3e-05
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
+TL+ L L +N++ LPK ++ + L L DN +S LP TI + L+ IS N +Q
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQ 143
Query: 284 SLPCSLMQCR-LEYIDISSN 302
P ++ C+ L I+ S N
Sbjct: 144 EFPENIKCCKCLTIIEASVN 163
Score = 35.5 bits (78), Expect = 0.34
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 173 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 232
L L L N+IE+LP + L +L + +N L + + + LK LD++
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLS-----NLPTTIASLVN--LKELDIS 138
Query: 233 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ- 291
N + P+ I + L ++A+ N IS+LP ++ L ++ L+ LP + +
Sbjct: 139 KNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRL 198
Query: 292 CRLEYIDISSNKFDNKQN 309
+L +++ N N
Sbjct: 199 VKLRILELRENHLKTLPN 216
>AF498274-1|AAP06801.1| 217|Homo sapiens densin-180 like protein
protein.
Length = 217
Score = 62.9 bits (146), Expect = 2e-09
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 140
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 141 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 196
Query: 268 RISTLRYFTISSNELQSLP 286
R+ LR + N L++LP
Sbjct: 197 RLVKLRILELRENHLKTLP 215
Score = 49.2 bits (112), Expect = 3e-05
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
+TL+ L L +N++ LPK ++ + L L DN +S LP TI + L+ IS N +Q
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQ 143
Query: 284 SLPCSLMQCR-LEYIDISSN 302
P ++ C+ L I+ S N
Sbjct: 144 EFPENIKCCKCLTIIEASVN 163
Score = 35.5 bits (78), Expect = 0.34
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 173 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 232
L L L N+IE+LP + L +L + +N L + + + LK LD++
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLS-----NLPTTIASLVN--LKELDIS 138
Query: 233 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ- 291
N + P+ I + L ++A+ N IS+LP ++ L ++ L+ LP + +
Sbjct: 139 KNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRL 198
Query: 292 CRLEYIDISSNKFDNKQN 309
+L +++ N N
Sbjct: 199 VKLRILELRENHLKTLPN 216
>BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 62.5 bits (145), Expect = 3e-09
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 2/136 (1%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR-GVVDWRWLLGPQITKTLKLL 229
+ ++ +DLS +E LP +L+ L+L N L + R L Q LK L
Sbjct: 125 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSL 184
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+L++N LG P A+ + L L + N + +PA +G + L+ F + N LQSLP L
Sbjct: 185 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 244
Query: 290 MQCR-LEYIDISSNKF 304
+ L Y+ +S N+F
Sbjct: 245 ENMKQLSYLGLSFNEF 260
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 14/150 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW--RWLLGPQ-- 221
++ L+H+ LDL +N++ L N+ LH NQL + + + L
Sbjct: 314 EVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDICGYFLKALYASSNE 371
Query: 222 --------ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
+ L +D++ N+L ++P+ + + KL L N I LPA + S+LR
Sbjct: 372 LVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLR 431
Query: 274 YFTISSNELQSLPCSLMQCRLEYIDISSNK 303
N+L LP L + +E +D+ N+
Sbjct: 432 KLLAGHNQLARLPERLERTSVEVLDVQHNQ 461
Score = 44.0 bits (99), Expect = 0.001
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 16/144 (11%)
Query: 168 LLLK--HLAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQI 222
LL+K L L+ S N++E LPP N L EL+L NN L + V P +
Sbjct: 469 LLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCV--------PLL 520
Query: 223 T--KTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
T LK+L + N+L P + + KLE+L + + N + +P TI + S
Sbjct: 521 TGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHS 580
Query: 280 NELQSLPCSLMQCRLEYIDISSNK 303
N ++ P + ++ +D+S N+
Sbjct: 581 NCIEVFPEVMQLPEIKCVDLSCNE 604
Score = 43.6 bits (98), Expect = 0.001
Identities = 39/152 (25%), Positives = 65/152 (42%), Gaps = 15/152 (9%)
Query: 143 AKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--------EFGRMA 194
+K + + S+ LS L + ++ + L L+L N + + P E R
Sbjct: 120 SKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFT 179
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKA 254
L L+L+NN LG + L TL L+++ N L +P A+ + L T
Sbjct: 180 KLKSLNLSNNHLG-------DFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLL 232
Query: 255 NDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+ N + LPA + + L Y +S NE +P
Sbjct: 233 DGNFLQSLPAELENMKQLSYLGLSFNEFTDIP 264
Score = 41.1 bits (92), Expect = 0.007
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
++ L++LD+ N++ LP ++ L L A N ++RLP + R S + + N+L
Sbjct: 404 SRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQL 462
Query: 283 QSLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 315
LP +L+ L +++ S+NK ++ + S++
Sbjct: 463 LELPPNLLMKADSLRFLNASANKLESLPPATLSEE 497
Score = 36.7 bits (81), Expect = 0.15
Identities = 50/187 (26%), Positives = 81/187 (43%), Gaps = 23/187 (12%)
Query: 138 RSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLS 197
RS A G+ LQ+ L G L + ++ +K L+ L LS NE +P ++ +
Sbjct: 215 RSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVD 274
Query: 198 ELHLANN---QLGVRGV--------VDWRW-----LLGPQIT--KTLKLLDLTSNKLGHL 239
+L ++ N L ++ + VD R L+ ++ + + LDL NKLG L
Sbjct: 275 KLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDL 334
Query: 240 PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDI 299
I+ + L N + L G L+ SSNEL L + L Y+D+
Sbjct: 335 DAMIFN--NIEVLHCERNQLVTLDIC-GYF--LKALYASSNELVQLDVYPVPNYLSYMDV 389
Query: 300 SSNKFDN 306
S N+ +N
Sbjct: 390 SRNRLEN 396
Score = 36.7 bits (81), Expect = 0.15
Identities = 49/180 (27%), Positives = 80/180 (44%), Gaps = 22/180 (12%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 205
+P L + +S +L N + + L VLD+ +N+I +LP ++L +L +NQ
Sbjct: 380 VPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQ 439
Query: 206 LG------------VRGVVDWRWL-LGPQI---TKTLKLLDLTSNKLGHLPKAIWKLEKL 249
L V V + L L P + +L+ L+ ++NKL LP A E
Sbjct: 440 LARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETN 499
Query: 250 VTLK----ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNK 303
L+ N+++ + + L+ ++ N LQS P S M LE ID+S NK
Sbjct: 500 SILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNK 559
>BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 62.5 bits (145), Expect = 3e-09
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 2/136 (1%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR-GVVDWRWLLGPQITKTLKLL 229
+ ++ +DLS +E LP +L+ L+L N L + R L Q LK L
Sbjct: 125 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSL 184
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+L++N LG P A+ + L L + N + +PA +G + L+ F + N LQSLP L
Sbjct: 185 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 244
Query: 290 MQCR-LEYIDISSNKF 304
+ L Y+ +S N+F
Sbjct: 245 ENMKQLSYLGLSFNEF 260
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 14/150 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW--RWLLGPQ-- 221
++ L+H+ LDL +N++ L N+ LH NQL + + + L
Sbjct: 314 EVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDICGYFLKALYASSNE 371
Query: 222 --------ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
+ L +D++ N+L ++P+ + + KL L N I LPA + S+LR
Sbjct: 372 LVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLR 431
Query: 274 YFTISSNELQSLPCSLMQCRLEYIDISSNK 303
N+L LP L + +E +D+ N+
Sbjct: 432 KLLAGHNQLARLPERLERTSVEVLDVQHNQ 461
Score = 44.0 bits (99), Expect = 0.001
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 16/144 (11%)
Query: 168 LLLK--HLAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQI 222
LL+K L L+ S N++E LPP N L EL+L NN L + V P +
Sbjct: 469 LLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCV--------PLL 520
Query: 223 T--KTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
T LK+L + N+L P + + KLE+L + + N + +P TI + S
Sbjct: 521 TGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHS 580
Query: 280 NELQSLPCSLMQCRLEYIDISSNK 303
N ++ P + ++ +D+S N+
Sbjct: 581 NCIEVFPEVMQLPEIKCVDLSCNE 604
Score = 43.6 bits (98), Expect = 0.001
Identities = 39/152 (25%), Positives = 65/152 (42%), Gaps = 15/152 (9%)
Query: 143 AKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--------EFGRMA 194
+K + + S+ LS L + ++ + L L+L N + + P E R
Sbjct: 120 SKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFT 179
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKA 254
L L+L+NN LG + L TL L+++ N L +P A+ + L T
Sbjct: 180 KLKSLNLSNNHLG-------DFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLL 232
Query: 255 NDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+ N + LPA + + L Y +S NE +P
Sbjct: 233 DGNFLQSLPAELENMKQLSYLGLSFNEFTDIP 264
Score = 41.1 bits (92), Expect = 0.007
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
++ L++LD+ N++ LP ++ L L A N ++RLP + R S + + N+L
Sbjct: 404 SRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQL 462
Query: 283 QSLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 315
LP +L+ L +++ S+NK ++ + S++
Sbjct: 463 LELPPNLLMKADSLRFLNASANKLESLPPATLSEE 497
Score = 36.7 bits (81), Expect = 0.15
Identities = 50/187 (26%), Positives = 81/187 (43%), Gaps = 23/187 (12%)
Query: 138 RSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLS 197
RS A G+ LQ+ L G L + ++ +K L+ L LS NE +P ++ +
Sbjct: 215 RSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVD 274
Query: 198 ELHLANN---QLGVRGV--------VDWRW-----LLGPQIT--KTLKLLDLTSNKLGHL 239
+L ++ N L ++ + VD R L+ ++ + + LDL NKLG L
Sbjct: 275 KLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDL 334
Query: 240 PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDI 299
I+ + L N + L G L+ SSNEL L + L Y+D+
Sbjct: 335 DAMIFN--NIEVLHCERNQLVTLDIC-GYF--LKALYASSNELVQLDVYPVPNYLSYMDV 389
Query: 300 SSNKFDN 306
S N+ +N
Sbjct: 390 SRNRLEN 396
Score = 36.7 bits (81), Expect = 0.15
Identities = 49/180 (27%), Positives = 80/180 (44%), Gaps = 22/180 (12%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 205
+P L + +S +L N + + L VLD+ +N+I +LP ++L +L +NQ
Sbjct: 380 VPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQ 439
Query: 206 LG------------VRGVVDWRWL-LGPQI---TKTLKLLDLTSNKLGHLPKAIWKLEKL 249
L V V + L L P + +L+ L+ ++NKL LP A E
Sbjct: 440 LARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETN 499
Query: 250 VTLK----ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNK 303
L+ N+++ + + L+ ++ N LQS P S M LE ID+S NK
Sbjct: 500 SILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNK 559
>AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ11062 fis, clone PLACE1004804, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 721
Score = 62.5 bits (145), Expect = 3e-09
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 2/136 (1%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR-GVVDWRWLLGPQITKTLKLL 229
+ ++ +DLS +E LP +L+ L+L N L + R L Q LK L
Sbjct: 125 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFAKLKSL 184
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+L++N LG P A+ + L L + N + +PA +G + L+ F + N LQSLP L
Sbjct: 185 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 244
Query: 290 MQCR-LEYIDISSNKF 304
+ L Y+ +S N+F
Sbjct: 245 ENMKQLSYLGLSFNEF 260
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 14/150 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW--RWLLGPQ-- 221
++ L+H+ LDL +N++ L N+ LH NQL + + + L
Sbjct: 314 EVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDICGYFLKALYASSNE 371
Query: 222 --------ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
+ L +D++ N+L ++P+ + + KL L N I LPA + S+LR
Sbjct: 372 LVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLR 431
Query: 274 YFTISSNELQSLPCSLMQCRLEYIDISSNK 303
N+L LP L + +E +D+ N+
Sbjct: 432 KLLAGHNQLARLPERLERTSVEVLDVQHNQ 461
Score = 45.2 bits (102), Expect = 4e-04
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 15/152 (9%)
Query: 143 AKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--------EFGRMA 194
+K + + S+ LS L + ++ + L L+L N + + P E R A
Sbjct: 120 SKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFA 179
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKA 254
L L+L+NN LG + L TL L+++ N L +P A+ + L T
Sbjct: 180 KLKSLNLSNNHLG-------DFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLL 232
Query: 255 NDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+ N + LPA + + L Y +S NE +P
Sbjct: 233 DGNFLQSLPAELENMKQLSYLGLSFNEFTDIP 264
Score = 44.0 bits (99), Expect = 0.001
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 16/144 (11%)
Query: 168 LLLK--HLAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQI 222
LL+K L L+ S N++E LPP N L EL+L NN L + V P +
Sbjct: 469 LLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCV--------PLL 520
Query: 223 T--KTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
T LK+L + N+L P + + KLE+L + + N + +P TI + S
Sbjct: 521 TGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHS 580
Query: 280 NELQSLPCSLMQCRLEYIDISSNK 303
N ++ P + ++ +D+S N+
Sbjct: 581 NCIEVFPEVMQLPEIKCVDLSCNE 604
Score = 41.1 bits (92), Expect = 0.007
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
++ L++LD+ N++ LP ++ L L A N ++RLP + R S + + N+L
Sbjct: 404 SRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQL 462
Query: 283 QSLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 315
LP +L+ L +++ S+NK ++ + S++
Sbjct: 463 LELPPNLLMKADSLRFLNASANKLESLPPATLSEE 497
Score = 36.7 bits (81), Expect = 0.15
Identities = 50/187 (26%), Positives = 81/187 (43%), Gaps = 23/187 (12%)
Query: 138 RSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLS 197
RS A G+ LQ+ L G L + ++ +K L+ L LS NE +P ++ +
Sbjct: 215 RSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVD 274
Query: 198 ELHLANN---QLGVRGV--------VDWRW-----LLGPQIT--KTLKLLDLTSNKLGHL 239
+L ++ N L ++ + VD R L+ ++ + + LDL NKLG L
Sbjct: 275 KLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDL 334
Query: 240 PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDI 299
I+ + L N + L G L+ SSNEL L + L Y+D+
Sbjct: 335 DAMIFN--NIEVLHCERNQLVTLDIC-GYF--LKALYASSNELVQLDVYPVPNYLSYMDV 389
Query: 300 SSNKFDN 306
S N+ +N
Sbjct: 390 SRNRLEN 396
Score = 36.7 bits (81), Expect = 0.15
Identities = 49/180 (27%), Positives = 80/180 (44%), Gaps = 22/180 (12%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 205
+P L + +S +L N + + L VLD+ +N+I +LP ++L +L +NQ
Sbjct: 380 VPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQ 439
Query: 206 LG------------VRGVVDWRWL-LGPQI---TKTLKLLDLTSNKLGHLPKAIWKLEKL 249
L V V + L L P + +L+ L+ ++NKL LP A E
Sbjct: 440 LARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETN 499
Query: 250 VTLK----ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNK 303
L+ N+++ + + L+ ++ N LQS P S M LE ID+S NK
Sbjct: 500 SILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNK 559
>AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein.
Length = 1369
Score = 62.5 bits (145), Expect = 3e-09
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 2/136 (1%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR-GVVDWRWLLGPQITKTLKLL 229
+ ++ +DLS +E LP +L+ L+L N L + R L Q LK L
Sbjct: 289 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSL 348
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+L++N LG P A+ + L L + N + +PA +G + L+ F + N LQSLP L
Sbjct: 349 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 408
Query: 290 MQCR-LEYIDISSNKF 304
+ L Y+ +S N+F
Sbjct: 409 ENMKQLSYLGLSFNEF 424
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 14/150 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW--RWLLGPQ-- 221
++ L+H+ LDL +N++ L N+ LH NQL + + + L
Sbjct: 478 EVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDICGYFLKALYASSNE 535
Query: 222 --------ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
+ L +D++ N+L ++P+ + + KL L N I LPA + S+LR
Sbjct: 536 LVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLR 595
Query: 274 YFTISSNELQSLPCSLMQCRLEYIDISSNK 303
N+L LP L + +E +D+ N+
Sbjct: 596 KLLAGHNQLARLPERLERTSVEVLDVQHNQ 625
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/144 (29%), Positives = 69/144 (47%), Gaps = 16/144 (11%)
Query: 168 LLLK--HLAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQI 222
LL+K L L+ S N++E LPP N L EL+L NN L + V P +
Sbjct: 633 LLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCV--------PLL 684
Query: 223 T--KTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
T LK+L + N+L P + + KLE+L + + N + +P TI S + S
Sbjct: 685 TGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCSRMHTVIAHS 744
Query: 280 NELQSLPCSLMQCRLEYIDISSNK 303
N ++ P + ++ +D+S N+
Sbjct: 745 NCIEVFPEVMQLPEIKCVDLSCNE 768
Score = 43.6 bits (98), Expect = 0.001
Identities = 39/152 (25%), Positives = 65/152 (42%), Gaps = 15/152 (9%)
Query: 143 AKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--------EFGRMA 194
+K + + S+ LS L + ++ + L L+L N + + P E R
Sbjct: 284 SKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFT 343
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKA 254
L L+L+NN LG + L TL L+++ N L +P A+ + L T
Sbjct: 344 KLKSLNLSNNHLG-------DFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLL 396
Query: 255 NDNMISRLPATIGRISTLRYFTISSNELQSLP 286
+ N + LPA + + L Y +S NE +P
Sbjct: 397 DGNFLQSLPAELENMKQLSYLGLSFNEFTDIP 428
Score = 41.1 bits (92), Expect = 0.007
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
++ L++LD+ N++ LP ++ L L A N ++RLP + R S + + N+L
Sbjct: 568 SRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQL 626
Query: 283 QSLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 315
LP +L+ L +++ S+NK ++ + S++
Sbjct: 627 LELPPNLLMKADSLRFLNASANKLESLPPATLSEE 661
Score = 36.7 bits (81), Expect = 0.15
Identities = 50/187 (26%), Positives = 81/187 (43%), Gaps = 23/187 (12%)
Query: 138 RSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLS 197
RS A G+ LQ+ L G L + ++ +K L+ L LS NE +P ++ +
Sbjct: 379 RSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVD 438
Query: 198 ELHLANN---QLGVRGV--------VDWRW-----LLGPQIT--KTLKLLDLTSNKLGHL 239
+L ++ N L ++ + VD R L+ ++ + + LDL NKLG L
Sbjct: 439 KLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDL 498
Query: 240 PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDI 299
I+ + L N + L G L+ SSNEL L + L Y+D+
Sbjct: 499 DAMIFN--NIEVLHCERNQLVTLDIC-GYF--LKALYASSNELVQLDVYPVPNYLSYMDV 553
Query: 300 SSNKFDN 306
S N+ +N
Sbjct: 554 SRNRLEN 560
Score = 36.7 bits (81), Expect = 0.15
Identities = 49/180 (27%), Positives = 80/180 (44%), Gaps = 22/180 (12%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 205
+P L + +S +L N + + L VLD+ +N+I +LP ++L +L +NQ
Sbjct: 544 VPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQ 603
Query: 206 LG------------VRGVVDWRWL-LGPQI---TKTLKLLDLTSNKLGHLPKAIWKLEKL 249
L V V + L L P + +L+ L+ ++NKL LP A E
Sbjct: 604 LARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETN 663
Query: 250 VTLK----ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNK 303
L+ N+++ + + L+ ++ N LQS P S M LE ID+S NK
Sbjct: 664 SILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNK 723
>J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precursor
protein.
Length = 545
Score = 61.7 bits (143), Expect = 5e-09
Identities = 53/146 (36%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLA 202
GLPR L+ L ++G N +I L L L L+ N +E LP F +A L LHL
Sbjct: 95 GLPR-LEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQ 153
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISR 261
NQL R L P +T LK L+L N L LP+ ++ L L TLK ++N +S
Sbjct: 154 GNQLQALP----RRLFQP-LTH-LKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSG 207
Query: 262 LP-ATIGRISTLRYFTISSNELQSLP 286
LP G++ +L+ + SN + LP
Sbjct: 208 LPQGVFGKLGSLQELFLDSNNISELP 233
Score = 47.2 bits (107), Expect = 1e-04
Identities = 46/144 (31%), Positives = 73/144 (50%), Gaps = 10/144 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG 207
L+SL+L G +L R + L HL L+L+ N + +LP E F + +L L L+NN L
Sbjct: 147 LESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALS 206
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLPATI 266
G+ + + G +L+ L L SN + LP ++ +L L L N I+ LP +I
Sbjct: 207 --GLP--QGVFGK--LGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSI 260
Query: 267 -GRISTLRYFTISSNELQSLPCSL 289
+ L + ++ N L+ LP L
Sbjct: 261 FASLGNLTFLSLQWNMLRVLPAGL 284
Score = 42.3 bits (95), Expect = 0.003
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 9/120 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L +L L L N + LP F L L L +NQL + L L+
Sbjct: 264 LGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHL------SNLRS 317
Query: 229 LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 286
L L+ N + HLP I++ LE+LV L N ++ L PA +S L ++S N+L +LP
Sbjct: 318 LMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLP 377
>BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 61.7 bits (143), Expect = 5e-09
Identities = 53/146 (36%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLA 202
GLPR L+ L ++G N +I L L L L+ N +E LP F +A L LHL
Sbjct: 95 GLPR-LEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQ 153
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISR 261
NQL R L P +T LK L+L N L LP+ ++ L L TLK ++N +S
Sbjct: 154 GNQLQALP----RRLFQP-LTH-LKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSG 207
Query: 262 LP-ATIGRISTLRYFTISSNELQSLP 286
LP G++ +L+ + SN + LP
Sbjct: 208 LPQGVFGKLGSLQELFLDSNNISELP 233
Score = 47.2 bits (107), Expect = 1e-04
Identities = 46/144 (31%), Positives = 73/144 (50%), Gaps = 10/144 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG 207
L+SL+L G +L R + L HL L+L+ N + +LP E F + +L L L+NN L
Sbjct: 147 LESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALS 206
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLPATI 266
G+ + + G +L+ L L SN + LP ++ +L L L N I+ LP +I
Sbjct: 207 --GLP--QGVFGK--LGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSI 260
Query: 267 -GRISTLRYFTISSNELQSLPCSL 289
+ L + ++ N L+ LP L
Sbjct: 261 FASLGNLTFLSLQWNMLRVLPAGL 284
Score = 42.3 bits (95), Expect = 0.003
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 9/120 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L +L L L N + LP F L L L +NQL + L L+
Sbjct: 264 LGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHL------SNLRS 317
Query: 229 LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 286
L L+ N + HLP I++ LE+LV L N ++ L PA +S L ++S N+L +LP
Sbjct: 318 LMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLP 377
>AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein 1
protein.
Length = 224
Score = 60.1 bits (139), Expect = 1e-08
Identities = 45/141 (31%), Positives = 71/141 (50%), Gaps = 10/141 (7%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
+I LK+L VL+ NN+IE+LP + + L L+L N+L G
Sbjct: 5 NIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP-------RGFGSLPA 57
Query: 226 LKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
L++LDLT N L LP + L L L +DN LP IG+++ L+ ++ N+L
Sbjct: 58 LEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLI 117
Query: 284 SLPCSLMQ-CRLEYIDISSNK 303
SLP + + +L+ + I N+
Sbjct: 118 SLPKEIGELTQLKELHIQGNR 138
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
TL++LYLS DI L L +L L +N++ LP E G + L ELH+ N+L V
Sbjct: 82 TLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 141
Score = 40.7 bits (91), Expect = 0.009
Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 14/122 (11%)
Query: 186 LPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--KTLKLLDLTSNKLGHLPKAI 243
+PP + NL L+ NNQ+ L QI+ + LK L+L N+L LP+
Sbjct: 2 VPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQKLKHLNLGMNRLNTLPRGF 52
Query: 244 WKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNELQSLPCSLMQ-CRLEYIDIS 300
L L L N +S LP ++TLR +S N+ + LP + + +L+ + +
Sbjct: 53 GSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLR 112
Query: 301 SN 302
N
Sbjct: 113 DN 114
>AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein.
Length = 1052
Score = 59.7 bits (138), Expect = 2e-08
Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMAN-LSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L VL L N +LPP + + L+EL +++N+L G L + L+
Sbjct: 86 LGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSAL------RELRK 139
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L+L+ N+L LP + L L L + N ++ LP ++ +S LR + N+L + P
Sbjct: 140 LNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQ 199
Query: 289 LMQ-CRLEYIDISSNK 303
L+Q LE +D+SSN+
Sbjct: 200 LLQLVALEELDVSSNR 215
Score = 59.7 bits (138), Expect = 2e-08
Identities = 53/160 (33%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L+ L LS +L + L HL LD+S N + LP ++ L L + +NQL
Sbjct: 135 RELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQL- 193
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
R LL Q+ L+ LD++SN+L LP+ I L L L + + LPA
Sbjct: 194 ---TAFPRQLL--QLV-ALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFC 247
Query: 268 RISTLRYFTISSNELQSLPC--SLMQCRLEYIDISSNKFD 305
+++L + +N LQ+LP S +Q RL+ +++SSN F+
Sbjct: 248 ELASLESLMLDNNGLQALPAQFSCLQ-RLKMLNLSSNLFE 286
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/155 (27%), Positives = 78/155 (50%), Gaps = 8/155 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S +L + + L L LD+ +N++ P + ++ L EL +++N+L R
Sbjct: 160 LEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRL--R 217
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
G+ + + LK+L L+ +LG LP +L L +L ++N + LPA +
Sbjct: 218 GLPE-----DISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCL 272
Query: 270 STLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 303
L+ +SSN + P +L+ LE + +S N+
Sbjct: 273 QRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQ 307
Score = 55.2 bits (127), Expect = 4e-07
Identities = 45/155 (29%), Positives = 77/155 (49%), Gaps = 8/155 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S +L DI L+ L +L LS E+ LP F +A+L L L NN G++
Sbjct: 206 LEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNN--GLQ 263
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
+ L + LK+L+L+SN P A+ L L L + N ++ +P+ I +
Sbjct: 264 ALPAQFSCL-----QRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGL 318
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 303
L + +N ++ LP S+++ LE + + N+
Sbjct: 319 GRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQ 353
Score = 53.6 bits (123), Expect = 1e-06
Identities = 46/150 (30%), Positives = 72/150 (48%), Gaps = 9/150 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 207
+L+SL L L L+ L +L+LS+N E+ P +A L EL+L+ NQL
Sbjct: 251 SLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTS 310
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V ++ LG +T L L +N++ +LP +I +L L L N I+ LP G
Sbjct: 311 VPSLISG---LGRLLT-----LWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFG 362
Query: 268 RISTLRYFTISSNELQSLPCSLMQCRLEYI 297
++S + + I N L P + + YI
Sbjct: 363 QLSRVGLWKIKDNPLIQPPYEVCMKGIPYI 392
Score = 52.8 bits (121), Expect = 2e-06
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 8/116 (6%)
Query: 172 HLAVLDLSNNEIEKLPPEF-GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 230
HL LD+S+N + L E + L +L+L++NQL LG L+ LD
Sbjct: 112 HLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQ-----LGA--LAHLEELD 164
Query: 231 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
++ N+L HLP ++ L +L TL + N ++ P + ++ L +SSN L+ LP
Sbjct: 165 VSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLP 220
Score = 51.6 bits (118), Expect = 5e-06
Identities = 42/139 (30%), Positives = 68/139 (48%), Gaps = 7/139 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L+ L+LSG +L L L L L NN ++ LP +F + L L+L++N
Sbjct: 227 RALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLF- 285
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
++ L P L+ L L+ N+L +P I L +L+TL ++N I LP +I
Sbjct: 286 ----EEFPAALLP--LAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIV 339
Query: 268 RISTLRYFTISSNELQSLP 286
++ L + N++ LP
Sbjct: 340 ELTGLEELVLQGNQIAVLP 358
>BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 4 protein.
Length = 683
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/135 (33%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT-LKL 228
L L L L +N + L P G + L+ L+L+ NQL LL P I + L++
Sbjct: 90 LVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLS---------LLPPYICQLPLRV 140
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L +++NKLG LP I L L L + N + LP+ + +S+LR + N+L +LP
Sbjct: 141 LIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTLPEE 200
Query: 289 LMQCRLEYIDISSNK 303
L L +D S N+
Sbjct: 201 LGDLPLVRLDFSCNR 215
Score = 54.4 bits (125), Expect = 7e-07
Identities = 48/148 (32%), Positives = 75/148 (50%), Gaps = 9/148 (6%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
PA G L L LS +L I L L VL +SNN++ LPP+ G + +L +L +
Sbjct: 108 PALGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDV 166
Query: 202 ANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR 261
++N+L L G +L+ L++ N+L LP+ + L LV L + N +SR
Sbjct: 167 SSNELQSLPSE----LCG---LSSLRDLNVRRNQLSTLPEELGDLP-LVRLDFSCNRVSR 218
Query: 262 LPATIGRISTLRYFTISSNELQSLPCSL 289
+P + R+ L+ + SN LQS P +
Sbjct: 219 IPVSFCRLRHLQVILLDSNPLQSPPAQV 246
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 12/134 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S KL DI L L LD+S+NE++ LP E +++L +L++ NQL
Sbjct: 138 LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTL 197
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
P+ L L LD + N++ +P + +L L + + N + PA +
Sbjct: 198 ----------PEELGDLPLVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQVC 247
Query: 268 RISTLRYFTISSNE 281
L F S E
Sbjct: 248 LKGKLHIFKYLSTE 261
Score = 44.0 bits (99), Expect = 0.001
Identities = 23/74 (31%), Positives = 38/74 (51%)
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL+ N+ +P+A +L L L N + L +G ++ L Y +S N+L LP +
Sbjct: 74 DLSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLSLLPPYI 133
Query: 290 MQCRLEYIDISSNK 303
Q L + +S+NK
Sbjct: 134 CQLPLRVLIVSNNK 147
>BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 2/83 (2%)
Query: 221 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 280
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 281 ELQSLPCSLMQCR-LEYIDISSN 302
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 7/116 (6%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 5e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 285 LPCSLMQCR-LEYIDISSNK 303
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.064
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 283
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 284 SLPCSLMQ-CRLEYIDISSNK 303
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
Score = 32.7 bits (71), Expect = 2.4
Identities = 26/104 (25%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
T++ L L +L D+ L L VL++ N++ +LP G + L L++ +N+L
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL-- 139
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTL 252
+ + D +G ++L+ L+++ N++ LP+ + + L L
Sbjct: 140 KELPD---TVGE--LRSLRTLNISGNEIQRLPQMLAHVRTLEML 178
>AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein
protein.
Length = 723
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 2/83 (2%)
Query: 221 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 280
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 281 ELQSLPCSLMQCR-LEYIDISSN 302
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 7/116 (6%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 5e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 285 LPCSLMQCR-LEYIDISSNK 303
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.064
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 283
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 284 SLPCSLMQ-CRLEYIDISSNK 303
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
Score = 32.7 bits (71), Expect = 2.4
Identities = 26/104 (25%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
T++ L L +L D+ L L VL++ N++ +LP G + L L++ +N+L
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL-- 139
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTL 252
+ + D +G ++L+ L+++ N++ LP+ + + L L
Sbjct: 140 KELPD---TVGE--LRSLRTLNISGNEIQRLPQMLAHVRTLEML 178
>AL445222-17|CAH72930.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 2/83 (2%)
Query: 221 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 280
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 281 ELQSLPCSLMQCR-LEYIDISSN 302
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 7/116 (6%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 5e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 285 LPCSLMQCR-LEYIDISSNK 303
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.064
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 283
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 284 SLPCSLMQ-CRLEYIDISSNK 303
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
Score = 32.7 bits (71), Expect = 2.4
Identities = 26/104 (25%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
T++ L L +L D+ L L VL++ N++ +LP G + L L++ +N+L
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL-- 139
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTL 252
+ + D +G ++L+ L+++ N++ LP+ + + L L
Sbjct: 140 KELPD---TVGE--LRSLRTLNISGNEIQRLPQMLAHVRTLEML 178
>AL445222-16|CAH72931.1| 696|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 696
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 2/83 (2%)
Query: 221 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 280
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 281 ELQSLPCSLMQCR-LEYIDISSN 302
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 7/116 (6%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 5e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 285 LPCSLMQCR-LEYIDISSNK 303
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.064
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 283
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 284 SLPCSLMQ-CRLEYIDISSNK 303
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
Score = 32.7 bits (71), Expect = 2.4
Identities = 26/104 (25%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
T++ L L +L D+ L L VL++ N++ +LP G + L L++ +N+L
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL-- 139
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTL 252
+ + D +G ++L+ L+++ N++ LP+ + + L L
Sbjct: 140 KELPD---TVGE--LRSLRTLNISGNEIQRLPQMLAHVRTLEML 178
>AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens
cDNA FLJ34270 fis, clone FEBRA2003100. ).
Length = 723
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 2/83 (2%)
Query: 221 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 280
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 281 ELQSLPCSLMQCR-LEYIDISSN 302
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 7/116 (6%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 5e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 285 LPCSLMQCR-LEYIDISSNK 303
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.064
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 283
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 284 SLPCSLMQ-CRLEYIDISSNK 303
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
Score = 32.7 bits (71), Expect = 2.4
Identities = 26/104 (25%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
T++ L L +L D+ L L VL++ N++ +LP G + L L++ +N+L
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL-- 139
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTL 252
+ + D +G ++L+ L+++ N++ LP+ + + L L
Sbjct: 140 KELPD---TVGE--LRSLRTLNISGNEIQRLPQMLAHVRTLEML 178
>AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens
cDNA FLJ31641 fis, clone NT2RI2003695, weakly similar to
TRICHOHYALIN. ).
Length = 696
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 2/83 (2%)
Query: 221 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 280
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 281 ELQSLPCSLMQCR-LEYIDISSN 302
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 7/116 (6%)
Query: 167 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 5e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 285 LPCSLMQCR-LEYIDISSNK 303
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.064
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 283
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 284 SLPCSLMQ-CRLEYIDISSNK 303
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
Score = 32.7 bits (71), Expect = 2.4
Identities = 26/104 (25%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
T++ L L +L D+ L L VL++ N++ +LP G + L L++ +N+L
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL-- 139
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTL 252
+ + D +G ++L+ L+++ N++ LP+ + + L L
Sbjct: 140 KELPD---TVGE--LRSLRTLNISGNEIQRLPQMLAHVRTLEML 178
>AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ10775 fis, clone NT2RP4000312, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 183
Score = 59.3 bits (137), Expect = 2e-08
Identities = 50/165 (30%), Positives = 79/165 (47%), Gaps = 17/165 (10%)
Query: 133 LVISDRSQFPAKGLPRT------LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKL 186
L ++D S P LP + L L ++ + L + +I L +LA L+L N + L
Sbjct: 26 LQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYL 85
Query: 187 PPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIW 244
P ++ L EL L NN++ + L I L L DL N+L LP+ I
Sbjct: 86 PDSLTQLRRLEELDLGNNEI---------YNLPESIGALLHLKDLWLDGNQLSELPQEIG 136
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
L+ L+ L ++N + RLP I +++L IS N L+++P L
Sbjct: 137 NLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGL 181
Score = 56.4 bits (130), Expect = 2e-07
Identities = 42/141 (29%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ LQ SG L L++L L +++ ++ LP G + NL+ L L N L
Sbjct: 24 KALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLL- 82
Query: 208 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 265
L +T+ +L LDL +N++ +LP++I L L L + N +S LP
Sbjct: 83 --------TYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQE 134
Query: 266 IGRISTLRYFTISSNELQSLP 286
IG + L +S N L+ LP
Sbjct: 135 IGNLKNLLCLDVSENRLERLP 155
Score = 54.4 bits (125), Expect = 7e-07
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 8/157 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L L +S ++ I K L V D S N + +LP F + NL+ L + N + ++
Sbjct: 3 LVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSV--NDISLQ 60
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
+ + +G L L+L N L +LP ++ +L +L L +N I LP +IG +
Sbjct: 61 SLPE---NIGN--LYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGAL 115
Query: 270 STLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 305
L+ + N+L LP + + L +D+S N+ +
Sbjct: 116 LHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLE 152
Score = 53.2 bits (122), Expect = 2e-06
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L++ D + N L LP++ +L+ L L ND + LP IG + L + N L
Sbjct: 24 KALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLT 83
Query: 284 SLPCSLMQC-RLEYIDISSNKFDN 306
LP SL Q RLE +D+ +N+ N
Sbjct: 84 YLPDSLTQLRRLEELDLGNNEIYN 107
>AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal
protein protein.
Length = 832
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/135 (33%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT-LKL 228
L L L L +N + L P G + L+ L+L+ NQL LL P I + L++
Sbjct: 90 LVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLS---------LLPPYICQLPLRV 140
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L +++NKLG LP I L L L + N + LP+ + +S+LR + N+L +LP
Sbjct: 141 LIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTLPEE 200
Query: 289 LMQCRLEYIDISSNK 303
L L +D S N+
Sbjct: 201 LGDLPLVRLDFSCNR 215
Score = 54.4 bits (125), Expect = 7e-07
Identities = 48/148 (32%), Positives = 75/148 (50%), Gaps = 9/148 (6%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
PA G L L LS +L I L L VL +SNN++ LPP+ G + +L +L +
Sbjct: 108 PALGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDV 166
Query: 202 ANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR 261
++N+L L G +L+ L++ N+L LP+ + L LV L + N +SR
Sbjct: 167 SSNELQSLPSE----LCG---LSSLRDLNVRRNQLSTLPEELGDLP-LVRLDFSCNRVSR 218
Query: 262 LPATIGRISTLRYFTISSNELQSLPCSL 289
+P + R+ L+ + SN LQS P +
Sbjct: 219 IPVSFCRLRHLQVILLDSNPLQSPPAQV 246
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 12/134 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S KL DI L L LD+S+NE++ LP E +++L +L++ NQL
Sbjct: 138 LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTL 197
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
P+ L L LD + N++ +P + +L L + + N + PA +
Sbjct: 198 ----------PEELGDLPLVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQVC 247
Query: 268 RISTLRYFTISSNE 281
L F S E
Sbjct: 248 LKGKLHIFKYLSTE 261
Score = 44.0 bits (99), Expect = 0.001
Identities = 23/74 (31%), Positives = 38/74 (51%)
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL+ N+ +P+A +L L L N + L +G ++ L Y +S N+L LP +
Sbjct: 74 DLSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLSLLPPYI 133
Query: 290 MQCRLEYIDISSNK 303
Q L + +S+NK
Sbjct: 134 CQLPLRVLIVSNNK 147
>BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kinase 2
protein.
Length = 2527
Score = 58.8 bits (136), Expect = 3e-08
Identities = 54/168 (32%), Positives = 82/168 (48%), Gaps = 11/168 (6%)
Query: 111 KALHLSP--LSSLSVTAKNNAPVKLVISDRSQFPAKG--LPRTLQSLYLSGLKLCNFRRD 166
K L+LS +SSLS P S R F A LP ++ L LS K
Sbjct: 1132 KILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIPEA 1191
Query: 167 ILLLKHLAVLDLSNNEIEKLP-PEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
IL L HL LD+S+N+I+ LP P + NL EL ++NQ+ + + + +L
Sbjct: 1192 ILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL-----WSR 1246
Query: 226 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM-ISRLPATIGRISTL 272
++ L L+ NKL +P I LE L +L + N+ + P +G++S +
Sbjct: 1247 VEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKI 1294
Score = 46.4 bits (105), Expect = 2e-04
Identities = 40/139 (28%), Positives = 69/139 (49%), Gaps = 10/139 (7%)
Query: 150 LQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
L+ L L L +F + + LK L LDL +N+ P +M+ ++ L ++ N +G
Sbjct: 1013 LEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGP 1072
Query: 209 RGVVDWRWLLGPQI-TKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATI 266
V+D P + TLK +L+ N+L +P+ + +EKL L N IS + + +
Sbjct: 1073 SVVLD------PTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL 1126
Query: 267 GRISTLRYFTISSNELQSL 285
R+ L+ +S N + SL
Sbjct: 1127 -RLKELKILNLSKNHISSL 1144
Score = 30.7 bits (66), Expect = 9.8
Identities = 52/212 (24%), Positives = 96/212 (45%), Gaps = 29/212 (13%)
Query: 115 LSPLSSLSVTAKNNAPVKLVISDRSQFPAKGLPRTLQSLY---LSGLKLCNFRRDILLLK 171
LS +SV ++ ++L + + FP + L TL+SL L K +F +L +
Sbjct: 1000 LSQKCCISVHLEHLEKLELHQNALTSFPQQ-LCETLKSLTHLDLHSNKFTSFPSYLLKMS 1058
Query: 172 HLAVLDLSNNEIEK---LPPEFGRMANLSELHLANNQL-----GVRGVVD---------- 213
+A LD+S N+I L P + L + +L+ NQL + VV+
Sbjct: 1059 CIANLDVSRNDIGPSVVLDPTV-KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query: 214 -WRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGRIST 271
+ P K LK+L+L+ N + L + + K+ + A N ++ +P ++
Sbjct: 1118 KISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTI 1177
Query: 272 LRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
L+ +S N+ +P +++ L +D+SSN
Sbjct: 1178 LK---LSQNKFSCIPEAILNLPHLRSLDMSSN 1206
>AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kinase 2
protein.
Length = 2527
Score = 58.8 bits (136), Expect = 3e-08
Identities = 54/168 (32%), Positives = 82/168 (48%), Gaps = 11/168 (6%)
Query: 111 KALHLSP--LSSLSVTAKNNAPVKLVISDRSQFPAKG--LPRTLQSLYLSGLKLCNFRRD 166
K L+LS +SSLS P S R F A LP ++ L LS K
Sbjct: 1132 KILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIPEA 1191
Query: 167 ILLLKHLAVLDLSNNEIEKLP-PEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 225
IL L HL LD+S+N+I+ LP P + NL EL ++NQ+ + + + +L
Sbjct: 1192 ILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL-----WSR 1246
Query: 226 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM-ISRLPATIGRISTL 272
++ L L+ NKL +P I LE L +L + N+ + P +G++S +
Sbjct: 1247 VEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKI 1294
Score = 46.4 bits (105), Expect = 2e-04
Identities = 40/139 (28%), Positives = 69/139 (49%), Gaps = 10/139 (7%)
Query: 150 LQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
L+ L L L +F + + LK L LDL +N+ P +M+ ++ L ++ N +G
Sbjct: 1013 LEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGP 1072
Query: 209 RGVVDWRWLLGPQI-TKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATI 266
V+D P + TLK +L+ N+L +P+ + +EKL L N IS + + +
Sbjct: 1073 SVVLD------PTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL 1126
Query: 267 GRISTLRYFTISSNELQSL 285
R+ L+ +S N + SL
Sbjct: 1127 -RLKELKILNLSKNHISSL 1144
Score = 30.7 bits (66), Expect = 9.8
Identities = 52/212 (24%), Positives = 96/212 (45%), Gaps = 29/212 (13%)
Query: 115 LSPLSSLSVTAKNNAPVKLVISDRSQFPAKGLPRTLQSLY---LSGLKLCNFRRDILLLK 171
LS +SV ++ ++L + + FP + L TL+SL L K +F +L +
Sbjct: 1000 LSQKCCISVHLEHLEKLELHQNALTSFPQQ-LCETLKSLTHLDLHSNKFTSFPSYLLKMS 1058
Query: 172 HLAVLDLSNNEIEK---LPPEFGRMANLSELHLANNQL-----GVRGVVD---------- 213
+A LD+S N+I L P + L + +L+ NQL + VV+
Sbjct: 1059 CIANLDVSRNDIGPSVVLDPTV-KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query: 214 -WRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGRIST 271
+ P K LK+L+L+ N + L + + K+ + A N ++ +P ++
Sbjct: 1118 KISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTI 1177
Query: 272 LRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
L+ +S N+ +P +++ L +D+SSN
Sbjct: 1178 LK---LSQNKFSCIPEAILNLPHLRSLDMSSN 1206
>AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 154
Score = 58.4 bits (135), Expect = 4e-08
Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 268 RIST 271
+ T
Sbjct: 149 KQKT 152
Score = 49.6 bits (113), Expect = 2e-05
Identities = 29/80 (36%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
++L+ L L +N+L LP+ ++L KL L +DN I RLP I L +S NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 284 SLPCSLMQCR-LEYIDISSN 302
+P S+ C+ L+ D S N
Sbjct: 96 EIPESISFCKALQVADFSGN 115
Score = 46.4 bits (105), Expect = 2e-04
Identities = 31/118 (26%), Positives = 62/118 (52%), Gaps = 11/118 (9%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL-- 228
+ L L L N++ +LP +F ++ L +L L++N++ L P+I ++L
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ---------RLPPEIANFMQLVE 86
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
LD++ N++ +P++I + L + N ++RLP + + L +++ LQSLP
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLP 144
>BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat
containing 59 protein.
Length = 307
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/106 (40%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 133 LVISDRSQFPAKGLPRTLQS--LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEF 190
L +SD ++ P K L ++ L LS KL D L HL LDLS N++++LP +F
Sbjct: 22 LSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADF 81
Query: 191 GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKL 236
GR+ NL L L NN+L V V + L K LK LDL N L
Sbjct: 82 GRLVNLQHLDLLNNKL-VTLPVSFAQL------KNLKWLDLKDNPL 120
Score = 56.0 bits (129), Expect = 2e-07
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+LDL+ NKL LP L LV L + N + +LPA GR+ L++ + +N+L +LP
Sbjct: 43 ILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPV 102
Query: 288 SLMQCR-LEYIDISSNKFD 305
S Q + L+++D+ N D
Sbjct: 103 SFAQLKNLKWLDLKDNPLD 121
Score = 40.7 bits (91), Expect = 0.009
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 7/102 (6%)
Query: 165 RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITK 224
+++ L +LDLS N++ LP +F + +L +L L+ N+L + D+ L+
Sbjct: 33 KELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQ-QLPADFGRLVN----- 86
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 266
L+ LDL +NKL LP + +L+ L L DN + + A +
Sbjct: 87 -LQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKV 127
Score = 36.7 bits (81), Expect = 0.15
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 229 LDLTSNKLGHLP-KAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
LDL+ + L +P K + L K L + N ++ LP+ ++ L +S N+LQ LP
Sbjct: 20 LDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPA 79
Query: 288 SLMQ-CRLEYIDISSNK 303
+ L+++D+ +NK
Sbjct: 80 DFGRLVNLQHLDLLNNK 96
>BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat
containing 59 protein.
Length = 307
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/106 (40%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 133 LVISDRSQFPAKGLPRTLQS--LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEF 190
L +SD ++ P K L ++ L LS KL D L HL LDLS N++++LP +F
Sbjct: 22 LSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADF 81
Query: 191 GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKL 236
GR+ NL L L NN+L V V + L K LK LDL N L
Sbjct: 82 GRLVNLQHLDLLNNKL-VTLPVSFAQL------KNLKWLDLKDNPL 120
Score = 56.0 bits (129), Expect = 2e-07
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
+LDL+ NKL LP L LV L + N + +LPA GR+ L++ + +N+L +LP
Sbjct: 43 ILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPV 102
Query: 288 SLMQCR-LEYIDISSNKFD 305
S Q + L+++D+ N D
Sbjct: 103 SFAQLKNLKWLDLKDNPLD 121
Score = 40.7 bits (91), Expect = 0.009
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 7/102 (6%)
Query: 165 RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITK 224
+++ L +LDLS N++ LP +F + +L +L L+ N+L + D+ L+
Sbjct: 33 KELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQ-QLPADFGRLVN----- 86
Query: 225 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 266
L+ LDL +NKL LP + +L+ L L DN + + A +
Sbjct: 87 -LQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKV 127
Score = 36.7 bits (81), Expect = 0.15
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 229 LDLTSNKLGHLP-KAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
LDL+ + L +P K + L K L + N ++ LP+ ++ L +S N+LQ LP
Sbjct: 20 LDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPA 79
Query: 288 SLMQ-CRLEYIDISSNK 303
+ L+++D+ +NK
Sbjct: 80 DFGRLVNLQHLDLLNNK 96
>AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and
death domain containing protein protein.
Length = 753
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 11/145 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L +L LS L + L L L +++N ++ LPP G ++ L L L+ N L
Sbjct: 2 RGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLD 61
Query: 208 VRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 265
L P+I +L L+L SN+L LP ++ L L L + N+++ +PA
Sbjct: 62 T---------LPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPAD 112
Query: 266 IGRISTLRYFTISSNELQSLPCSLM 290
+ R+ L + N+L+ LP L+
Sbjct: 113 LARLPLLTRLDLRDNQLRDLPPELL 137
Score = 54.0 bits (124), Expect = 9e-07
Identities = 42/135 (31%), Positives = 66/135 (48%), Gaps = 8/135 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
++ L L LS+N + +LP G + L+ L + +N+L LG TL+ L
Sbjct: 1 MRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPA-----LGA--LSTLQRL 53
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL+ N L LP I L L+ L N + LPA++ + +LR + SN L S+P L
Sbjct: 54 DLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADL 113
Query: 290 MQC-RLEYIDISSNK 303
+ L +D+ N+
Sbjct: 114 ARLPLLTRLDLRDNQ 128
Score = 31.5 bits (68), Expect = 5.6
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 7/99 (7%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
PA G TLQ L LS L +I L L L+L++N ++ LP + +L L L
Sbjct: 42 PALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVL 101
Query: 202 ANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP 240
+N L D L P +T+ LDL N+L LP
Sbjct: 102 HSNLL-ASVPADLARL--PLLTR----LDLRDNQLRDLP 133
>AY358137-1|AAQ88504.1| 255|Homo sapiens VKGE9338 protein.
Length = 255
Score = 56.8 bits (131), Expect = 1e-07
Identities = 33/111 (29%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLKLL 229
++L LDL +N I+KLP G+M +L L+++NN+L G+ V+ + L K ++ +
Sbjct: 73 QNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQL------KNIRAV 126
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 280
+L N L +P + L++L + +DN+++ +P +I ++ L+ I N
Sbjct: 127 NLGLNHLDSVPTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRN 177
Score = 50.8 bits (116), Expect = 9e-06
Identities = 43/155 (27%), Positives = 77/155 (49%), Gaps = 10/155 (6%)
Query: 153 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 212
L LS + + F + IL L + LDLS N I K+P + NL L L +N +
Sbjct: 32 LDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYID----- 86
Query: 213 DWRWLLGPQITKTLKLLDLTSNKL--GHLPKAIWKLEKLVTLKANDNMISRLPATIGRIS 270
+G Q+T +L L++++N+L LP + +L+ + + N + +P T+G +
Sbjct: 87 KLPESIG-QMT-SLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVPTTLGALK 144
Query: 271 TLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKF 304
L + N L ++P S+ + +L+ ++I N F
Sbjct: 145 ELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPF 179
Score = 49.6 bits (113), Expect = 2e-05
Identities = 27/81 (33%), Positives = 47/81 (58%), Gaps = 3/81 (3%)
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS--LP 286
LDL+ N + +P +I K + L L + N I +LP +IG++++L Y +S+N L S LP
Sbjct: 55 LDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLP 114
Query: 287 CSLMQCR-LEYIDISSNKFDN 306
L Q + + +++ N D+
Sbjct: 115 VELKQLKNIRAVNLGLNHLDS 135
Score = 47.2 bits (107), Expect = 1e-04
Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
K LDL+ + PK I +L + L + N+I ++P +I + LR+ + SN + LP
Sbjct: 30 KRLDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLP 89
Query: 287 CSLMQ-CRLEYIDISSNK 303
S+ Q L Y+++S+N+
Sbjct: 90 ESIGQMTSLLYLNVSNNR 107
>AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich
repeat-containing 2 protein protein.
Length = 371
Score = 56.8 bits (131), Expect = 1e-07
Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ Y+S + I L + + +LDL N+I LP E G + NL EL++ N L +
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQEMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYL--K 180
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSN-KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ LG + L+ LD + N +L LP + L+++ + + N S +P + R
Sbjct: 181 SIPP---ELGD--CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLR 235
Query: 269 ISTLRYFTISSNELQSLP 286
+S L++ ISSN L LP
Sbjct: 236 MSNLQWLDISSNNLTDLP 253
Score = 49.6 bits (113), Expect = 2e-05
Identities = 44/174 (25%), Positives = 82/174 (47%), Gaps = 11/174 (6%)
Query: 139 SQFPAK-GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNN-EIEKLPPEFGRMANL 196
S PA+ G + L+ L + L + ++ ++L LD S N E+ +LP E + +
Sbjct: 157 SHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQV 216
Query: 197 SELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKAND 256
+ + ++ N+ + R L+ LD++SN L LP+ I +LE+L +
Sbjct: 217 TFVDISANKFSSVPICVLRM-------SNLQWLDISSNNLTDLPQDIDRLEELQSFLLYK 269
Query: 257 NMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR--LEYIDISSNKFDNKQ 308
N ++ LP ++ + L +S + L LP +L L+++ + N DN Q
Sbjct: 270 NKLTYLPYSMLNLKKLTLLVVSGDHLVELPTALCDSSTPLKFVSLMDNPIDNAQ 323
Score = 40.3 bits (90), Expect = 0.012
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 239 LPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYI 297
+P I +++ L N IS LPA IG + L+ + N L+S+P L C LE +
Sbjct: 136 IPTYIQLFQEMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERL 195
Query: 298 DISSN 302
D S N
Sbjct: 196 DCSGN 200
>BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat
containing 2 protein.
Length = 371
Score = 56.4 bits (130), Expect = 2e-07
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 9/134 (6%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
V +LS +LP +L E +++N + + Q+ + +++LDL N
Sbjct: 102 VFELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYI-------QLFQAMRILDLPKN 154
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN-ELQSLPCSLMQCR 293
++ HLP I L+ L L N + +P +G L S N EL LP L +
Sbjct: 155 QISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLK 214
Query: 294 -LEYIDISSNKFDN 306
+ ++DIS+NKF +
Sbjct: 215 QVTFVDISANKFSS 228
Score = 56.0 bits (129), Expect = 2e-07
Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ Y+S + I L + + +LDL N+I LP E G + NL EL++ N L +
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYL--K 180
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSN-KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ LG + L+ LD + N +L LP + L+++ + + N S +P + R
Sbjct: 181 SIPP---ELGD--CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLR 235
Query: 269 ISTLRYFTISSNELQSLP 286
+S L++ ISSN L LP
Sbjct: 236 MSNLQWLDISSNNLTDLP 253
Score = 54.4 bits (125), Expect = 7e-07
Identities = 36/146 (24%), Positives = 73/146 (50%), Gaps = 6/146 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ ++ L L ++ + +I LK+L L++ N ++ +PPE G NL L + N
Sbjct: 144 QAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGN--- 200
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+++ + L K + +D+++NK +P + ++ L L + N ++ LP I
Sbjct: 201 -LELMELPFELSN--LKQVTFVDISANKFSSVPICVLRMSNLQWLDISSNNLTDLPQDID 257
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR 293
R+ L+ F + N+L LP S++ +
Sbjct: 258 RLEELQSFLLYKNKLTYLPYSMLNLK 283
Score = 49.6 bits (113), Expect = 2e-05
Identities = 44/174 (25%), Positives = 82/174 (47%), Gaps = 11/174 (6%)
Query: 139 SQFPAK-GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNN-EIEKLPPEFGRMANL 196
S PA+ G + L+ L + L + ++ ++L LD S N E+ +LP E + +
Sbjct: 157 SHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQV 216
Query: 197 SELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKAND 256
+ + ++ N+ + R L+ LD++SN L LP+ I +LE+L +
Sbjct: 217 TFVDISANKFSSVPICVLRM-------SNLQWLDISSNNLTDLPQDIDRLEELQSFLLYK 269
Query: 257 NMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR--LEYIDISSNKFDNKQ 308
N ++ LP ++ + L +S + L LP +L L+++ + N DN Q
Sbjct: 270 NKLTYLPYSMLNLKKLTLLVVSGDHLVELPTALCDSSTPLKFVSLMDNPIDNAQ 323
>AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat
containing 2 variant protein.
Length = 371
Score = 56.4 bits (130), Expect = 2e-07
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 9/134 (6%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
V +LS +LP +L E +++N + + Q+ + +++LDL N
Sbjct: 102 VFELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYI-------QLFQAMRILDLPKN 154
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN-ELQSLPCSLMQCR 293
++ HLP I L+ L L N + +P +G L S N EL LP L +
Sbjct: 155 QISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLK 214
Query: 294 -LEYIDISSNKFDN 306
+ ++DIS+NKF +
Sbjct: 215 QVTFVDISANKFSS 228
Score = 56.0 bits (129), Expect = 2e-07
Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ Y+S + I L + + +LDL N+I LP E G + NL EL++ N L +
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYL--K 180
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSN-KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ LG + L+ LD + N +L LP + L+++ + + N S +P + R
Sbjct: 181 SIPP---ELGD--CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLR 235
Query: 269 ISTLRYFTISSNELQSLP 286
+S L++ ISSN L LP
Sbjct: 236 MSNLQWLDISSNNLTDLP 253
Score = 54.4 bits (125), Expect = 7e-07
Identities = 36/146 (24%), Positives = 73/146 (50%), Gaps = 6/146 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ ++ L L ++ + +I LK+L L++ N ++ +PPE G NL L + N
Sbjct: 144 QAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGN--- 200
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+++ + L K + +D+++NK +P + ++ L L + N ++ LP I
Sbjct: 201 -LELMELPFELSN--LKQVTFVDISANKFSSVPICVLRMSNLQWLDISSNNLTDLPQDID 257
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR 293
R+ L+ F + N+L LP S++ +
Sbjct: 258 RLEELQSFLLYKNKLTYLPYSMLNLK 283
Score = 49.6 bits (113), Expect = 2e-05
Identities = 44/174 (25%), Positives = 82/174 (47%), Gaps = 11/174 (6%)
Query: 139 SQFPAK-GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNN-EIEKLPPEFGRMANL 196
S PA+ G + L+ L + L + ++ ++L LD S N E+ +LP E + +
Sbjct: 157 SHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQV 216
Query: 197 SELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKAND 256
+ + ++ N+ + R L+ LD++SN L LP+ I +LE+L +
Sbjct: 217 TFVDISANKFSSVPICVLRM-------SNLQWLDISSNNLTDLPQDIDRLEELQSFLLYK 269
Query: 257 NMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR--LEYIDISSNKFDNKQ 308
N ++ LP ++ + L +S + L LP +L L+++ + N DN Q
Sbjct: 270 NKLTYLPYSMLNLKKLTLLVVSGDHLVELPTALCDSSTPLKFVSLMDNPIDNAQ 323
>AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens
cDNA FLJ25079 fis, clone CBL07055. ).
Length = 371
Score = 56.4 bits (130), Expect = 2e-07
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 9/134 (6%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
V +LS +LP +L E +++N + + Q+ + +++LDL N
Sbjct: 102 VFELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYI-------QLFQAMRILDLPKN 154
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN-ELQSLPCSLMQCR 293
++ HLP I L+ L L N + +P +G L S N EL LP L +
Sbjct: 155 QISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLK 214
Query: 294 -LEYIDISSNKFDN 306
+ ++DIS+NKF +
Sbjct: 215 QVTFVDISANKFSS 228
Score = 56.0 bits (129), Expect = 2e-07
Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ Y+S + I L + + +LDL N+I LP E G + NL EL++ N L +
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYL--K 180
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSN-KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ LG + L+ LD + N +L LP + L+++ + + N S +P + R
Sbjct: 181 SIPP---ELGD--CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLR 235
Query: 269 ISTLRYFTISSNELQSLP 286
+S L++ ISSN L LP
Sbjct: 236 MSNLQWLDISSNNLTDLP 253
Score = 54.4 bits (125), Expect = 7e-07
Identities = 36/146 (24%), Positives = 73/146 (50%), Gaps = 6/146 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
+ ++ L L ++ + +I LK+L L++ N ++ +PPE G NL L + N
Sbjct: 144 QAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGN--- 200
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+++ + L K + +D+++NK +P + ++ L L + N ++ LP I
Sbjct: 201 -LELMELPFELSN--LKQVTFVDISANKFSSVPICVLRMSNLQWLDISSNNLTDLPQDID 257
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR 293
R+ L+ F + N+L LP S++ +
Sbjct: 258 RLEELQSFLLYKNKLTYLPYSMLNLK 283
Score = 49.6 bits (113), Expect = 2e-05
Identities = 44/174 (25%), Positives = 82/174 (47%), Gaps = 11/174 (6%)
Query: 139 SQFPAK-GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNN-EIEKLPPEFGRMANL 196
S PA+ G + L+ L + L + ++ ++L LD S N E+ +LP E + +
Sbjct: 157 SHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQV 216
Query: 197 SELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKAND 256
+ + ++ N+ + R L+ LD++SN L LP+ I +LE+L +
Sbjct: 217 TFVDISANKFSSVPICVLRM-------SNLQWLDISSNNLTDLPQDIDRLEELQSFLLYK 269
Query: 257 NMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR--LEYIDISSNKFDNKQ 308
N ++ LP ++ + L +S + L LP +L L+++ + N DN Q
Sbjct: 270 NKLTYLPYSMLNLKKLTLLVVSGDHLVELPTALCDSSTPLKFVSLMDNPIDNAQ 323
>BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 7/125 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 661 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 713
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 714 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 773
Query: 290 MQCRL 294
+C L
Sbjct: 774 GECPL 778
Score = 49.6 bits (113), Expect = 2e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 217
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 590 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query: 218 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 650 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 709
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L+ I++N +++LP L QCR L + + +N
Sbjct: 710 LQNLAITANRIETLPPELFQCRKLRALHLGNN 741
Score = 48.8 bits (111), Expect = 3e-05
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 664 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 722
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L P++ + KL L L +N L LP + +L L ++ N + LP +G
Sbjct: 723 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 268 RISTLR 273
L+
Sbjct: 775 ECPLLK 780
Score = 41.1 bits (92), Expect = 0.007
Identities = 26/59 (44%), Positives = 32/59 (54%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 685 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 743
Score = 39.5 bits (88), Expect = 0.021
Identities = 18/62 (29%), Positives = 34/62 (54%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + LQ+L ++ ++ ++ + L L L NN ++ LP G + NL+++ L N
Sbjct: 705 GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 764
Query: 205 QL 206
+L
Sbjct: 765 RL 766
>BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat
containing 47 protein.
Length = 583
Score = 56.0 bits (129), Expect = 2e-07
Identities = 56/178 (31%), Positives = 86/178 (48%), Gaps = 19/178 (10%)
Query: 143 AKGLPRTLQSLYLSGLKLC-NFRRDILLLKHLAVLDLSNNEIEKLPPEFGR-------MA 194
A+GLP+ L SL L L ++ L L VLDLS N +E LPP G +
Sbjct: 71 AQGLPQ-LHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLP 129
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK---LEKLVT 251
L L+L+ N+L R + P+ L+ L+LT N L P +++ L L
Sbjct: 130 QLQSLNLSGNRL--RELPADLARCAPR----LQSLNLTGNCLDSFPAELFRPGALPLLSE 183
Query: 252 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDNKQ 308
L A DN + L I +++L+ +S+N+L +P L C +L+ I+ NK +K+
Sbjct: 184 LAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLRDKR 241
>AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein.
Length = 546
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 7/125 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 397 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 449
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 450 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 509
Query: 290 MQCRL 294
+C L
Sbjct: 510 GECPL 514
Score = 49.6 bits (113), Expect = 2e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 217
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 326 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 385
Query: 218 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 386 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 445
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L+ I++N +++LP L QCR L + + +N
Sbjct: 446 LQNLAITANRIETLPPELFQCRKLRALHLGNN 477
Score = 48.8 bits (111), Expect = 3e-05
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 400 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 458
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L P++ + KL L L +N L LP + +L L ++ N + LP +G
Sbjct: 459 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 510
Query: 268 RISTLR 273
L+
Sbjct: 511 ECPLLK 516
Score = 41.1 bits (92), Expect = 0.007
Identities = 26/59 (44%), Positives = 32/59 (54%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 421 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 479
Score = 39.5 bits (88), Expect = 0.021
Identities = 18/62 (29%), Positives = 34/62 (54%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + LQ+L ++ ++ ++ + L L L NN ++ LP G + NL+++ L N
Sbjct: 441 GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 500
Query: 205 QL 206
+L
Sbjct: 501 RL 502
>AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich
repeat-containing 8 protein.
Length = 810
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 7/125 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 661 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 713
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 714 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 773
Query: 290 MQCRL 294
+C L
Sbjct: 774 GECPL 778
Score = 49.6 bits (113), Expect = 2e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 217
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 590 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query: 218 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 650 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 709
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L+ I++N +++LP L QCR L + + +N
Sbjct: 710 LQNLAITANRIETLPPELFQCRKLRALHLGNN 741
Score = 48.8 bits (111), Expect = 3e-05
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 664 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 722
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L P++ + KL L L +N L LP + +L L ++ N + LP +G
Sbjct: 723 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 268 RISTLR 273
L+
Sbjct: 775 ECPLLK 780
Score = 41.1 bits (92), Expect = 0.007
Identities = 26/59 (44%), Positives = 32/59 (54%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 685 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 743
Score = 39.5 bits (88), Expect = 0.021
Identities = 18/62 (29%), Positives = 34/62 (54%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + LQ+L ++ ++ ++ + L L L NN ++ LP G + NL+++ L N
Sbjct: 705 GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 764
Query: 205 QL 206
+L
Sbjct: 765 RL 766
>AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 7/125 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 661 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 713
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 714 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 773
Query: 290 MQCRL 294
+C L
Sbjct: 774 GECPL 778
Score = 49.6 bits (113), Expect = 2e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 217
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 590 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query: 218 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 650 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 709
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L+ I++N +++LP L QCR L + + +N
Sbjct: 710 LQNLAITANRIETLPPELFQCRKLRALHLGNN 741
Score = 48.8 bits (111), Expect = 3e-05
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 664 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 722
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L P++ + KL L L +N L LP + +L L ++ N + LP +G
Sbjct: 723 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 268 RISTLR 273
L+
Sbjct: 775 ECPLLK 780
Score = 41.1 bits (92), Expect = 0.007
Identities = 26/59 (44%), Positives = 32/59 (54%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 685 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 743
Score = 39.5 bits (88), Expect = 0.021
Identities = 18/62 (29%), Positives = 34/62 (54%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + LQ+L ++ ++ ++ + L L L NN ++ LP G + NL+++ L N
Sbjct: 705 GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 764
Query: 205 QL 206
+L
Sbjct: 765 RL 766
>AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat
containing 47 protein.
Length = 583
Score = 56.0 bits (129), Expect = 2e-07
Identities = 56/178 (31%), Positives = 86/178 (48%), Gaps = 19/178 (10%)
Query: 143 AKGLPRTLQSLYLSGLKLC-NFRRDILLLKHLAVLDLSNNEIEKLPPEFGR-------MA 194
A+GLP+ L SL L L ++ L L VLDLS N +E LPP G +
Sbjct: 71 AQGLPQ-LHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLP 129
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK---LEKLVT 251
L L+L+ N+L R + P+ L+ L+LT N L P +++ L L
Sbjct: 130 QLQSLNLSGNRL--RELPADLARCAPR----LQSLNLTGNCLDSFPAELFRPGALPLLSE 183
Query: 252 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDNKQ 308
L A DN + L I +++L+ +S+N+L +P L C +L+ I+ NK +K+
Sbjct: 184 LAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLRDKR 241
>AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens
cDNA FLJ14589 fis, clone NT2RM4001876, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 474
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 7/125 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 325 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 377
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 378 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 437
Query: 290 MQCRL 294
+C L
Sbjct: 438 GECPL 442
Score = 49.6 bits (113), Expect = 2e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 217
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 254 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 313
Query: 218 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 314 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 373
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L+ I++N +++LP L QCR L + + +N
Sbjct: 374 LQNLAITANRIETLPPELFQCRKLRALHLGNN 405
Score = 48.8 bits (111), Expect = 3e-05
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 328 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 386
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L P++ + KL L L +N L LP + +L L ++ N + LP +G
Sbjct: 387 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 438
Query: 268 RISTLR 273
L+
Sbjct: 439 ECPLLK 444
Score = 41.1 bits (92), Expect = 0.007
Identities = 26/59 (44%), Positives = 32/59 (54%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 349 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 407
Score = 39.5 bits (88), Expect = 0.021
Identities = 18/62 (29%), Positives = 34/62 (54%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + LQ+L ++ ++ ++ + L L L NN ++ LP G + NL+++ L N
Sbjct: 369 GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 428
Query: 205 QL 206
+L
Sbjct: 429 RL 430
>AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens
cDNA FLJ10337 fis, clone NT2RM2000714, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 221
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 7/125 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 72 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 124
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 125 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 184
Query: 290 MQCRL 294
+C L
Sbjct: 185 GECPL 189
Score = 49.2 bits (112), Expect = 3e-05
Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWLLGPQITKTLKL 228
+ +L L+L ++E++P + NL E+ L ++ L + ++ ++ L L
Sbjct: 1 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDDNLKTIEEIISFQHL------HRLTC 54
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L L N + ++P I L L L N N I ++P + LRY +S N L LP
Sbjct: 55 LKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD 114
Query: 289 L-MQCRLEYIDISSNKFD 305
+ + L+ + I++N+ +
Sbjct: 115 IGLLQNLQNLAITANRIE 132
Score = 48.8 bits (111), Expect = 3e-05
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 75 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 133
Query: 210 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L P++ + L+ L L +N L LP + +L L ++ N + LP +G
Sbjct: 134 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 185
Query: 268 RISTLR 273
L+
Sbjct: 186 ECPLLK 191
Score = 48.4 bits (110), Expect = 5e-05
Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Query: 226 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L+ L L NK+ +P ++ KL L + N ++ LPA IG + L+ I++N +++L
Sbjct: 75 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETL 134
Query: 286 PCSLMQCR-LEYIDISSN 302
P L QCR L + + +N
Sbjct: 135 PPELFQCRKLRALHLGNN 152
Score = 41.1 bits (92), Expect = 0.007
Identities = 26/59 (44%), Positives = 32/59 (54%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 96 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 154
Score = 39.5 bits (88), Expect = 0.021
Identities = 18/62 (29%), Positives = 34/62 (54%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + LQ+L ++ ++ ++ + L L L NN ++ LP G + NL+++ L N
Sbjct: 116 GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 175
Query: 205 QL 206
+L
Sbjct: 176 RL 177
>AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein.
Length = 811
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 7/125 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 662 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 714
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 715 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 774
Query: 290 MQCRL 294
+C L
Sbjct: 775 GECPL 779
Score = 49.6 bits (113), Expect = 2e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 217
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 591 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 650
Query: 218 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 651 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 710
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L+ I++N +++LP L QCR L + + +N
Sbjct: 711 LQNLAITANRIETLPPELFQCRKLRALHLGNN 742
Score = 48.8 bits (111), Expect = 3e-05
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 665 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 723
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L P++ + KL L L +N L LP + +L L ++ N + LP +G
Sbjct: 724 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 775
Query: 268 RISTLR 273
L+
Sbjct: 776 ECPLLK 781
Score = 41.1 bits (92), Expect = 0.007
Identities = 26/59 (44%), Positives = 32/59 (54%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 686 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 744
Score = 39.5 bits (88), Expect = 0.021
Identities = 18/62 (29%), Positives = 34/62 (54%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + LQ+L ++ ++ ++ + L L L NN ++ LP G + NL+++ L N
Sbjct: 706 GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 765
Query: 205 QL 206
+L
Sbjct: 766 RL 767
>BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein.
Length = 580
Score = 55.6 bits (128), Expect = 3e-07
Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Query: 186 LPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT-LKLLDLTSNKLGHLPKAIW 244
L P G + L+ L+L+ NQL LL P I + L++L +++NKLG LP I
Sbjct: 3 LNPALGNLTALTYLNLSRNQLS---------LLPPYICQLPLRVLIVSNNKLGALPPDIG 53
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
L L L + N + LP+ + +S+LR + N+L +LP L L +D S N+
Sbjct: 54 TLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDLPLVRLDFSCNR 112
Score = 54.4 bits (125), Expect = 7e-07
Identities = 48/148 (32%), Positives = 75/148 (50%), Gaps = 9/148 (6%)
Query: 142 PAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHL 201
PA G L L LS +L I L L VL +SNN++ LPP+ G + +L +L +
Sbjct: 5 PALGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDV 63
Query: 202 ANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR 261
++N+L L G +L+ L++ N+L LP+ + L LV L + N +SR
Sbjct: 64 SSNELQSLPSE----LCG---LSSLRDLNVRRNQLSTLPEELGDLP-LVRLDFSCNRVSR 115
Query: 262 LPATIGRISTLRYFTISSNELQSLPCSL 289
+P + R+ L+ + SN LQS P +
Sbjct: 116 IPVSFCRLRHLQVILLDSNPLQSPPAQV 143
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 12/134 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S KL DI L L LD+S+NE++ LP E +++L +L++ NQL
Sbjct: 35 LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTL 94
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
P+ L L LD + N++ +P + +L L + + N + PA +
Sbjct: 95 ----------PEELGDLPLVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQVC 144
Query: 268 RISTLRYFTISSNE 281
L F S E
Sbjct: 145 LKGKLHIFKYLSTE 158
>AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens
cDNA FLJ90242 fis, clone NT2RM2001626, highly similar to
Leucine-rich repeat-containing protein 8 precursor. ).
Length = 546
Score = 55.6 bits (128), Expect = 3e-07
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 7/125 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 397 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 449
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 450 AITANRIETLPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLPVEL 509
Query: 290 MQCRL 294
+C L
Sbjct: 510 GECPL 514
Score = 49.6 bits (113), Expect = 2e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 217
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 326 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 385
Query: 218 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 386 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 445
Query: 272 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 302
L+ I++N +++LP L QCR L + + +N
Sbjct: 446 LQNLAITANRIETLPPELFQCRKLRALHLGNN 477
Score = 48.8 bits (111), Expect = 3e-05
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 400 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 458
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
L P++ + KL L L +N L LP + +L L ++ N + LP +G
Sbjct: 459 --------LPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLPVELG 510
Query: 268 RISTLR 273
L+
Sbjct: 511 ECPLLK 516
Score = 41.1 bits (92), Expect = 0.007
Identities = 26/59 (44%), Positives = 32/59 (54%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 421 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 479
Score = 38.7 bits (86), Expect = 0.037
Identities = 18/62 (29%), Positives = 33/62 (53%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + LQ+L ++ ++ ++ + L L L NN + LP G + NL+++ L N
Sbjct: 441 GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGN 500
Query: 205 QL 206
+L
Sbjct: 501 RL 502
>BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte
differentiation 158 protein.
Length = 803
Score = 54.8 bits (126), Expect = 5e-07
Identities = 37/139 (26%), Positives = 73/139 (52%), Gaps = 8/139 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GVRGVVDWRWLLGPQITKTLKL 228
+ +L L+L + ++E++P + +L EL L N L + +V ++ L + L +
Sbjct: 588 MTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHL------RKLTV 641
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L L N + ++P+ I KL L L + N I LP+ + + +RY +S N+++ +P
Sbjct: 642 LKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPE 701
Query: 289 L-MQCRLEYIDISSNKFDN 306
+ + L+Y I+ NK ++
Sbjct: 702 IGVLQSLQYFSITCNKVES 720
Score = 52.4 bits (120), Expect = 3e-06
Identities = 57/213 (26%), Positives = 94/213 (44%), Gaps = 24/213 (11%)
Query: 101 LLRSCITGD-EKALHLSPLSSLSVTAKNNAPVKLVISDRSQFP-AKGLPRTLQSLYLSGL 158
L + CI D K + L+ L ++ N ++LV D + P A +LQ L L
Sbjct: 567 LQKMCIHNDGTKLVMLNNLKKMT----NLTELELVHCDLERIPHAVFSLLSLQELDLKEN 622
Query: 159 KLCNFRRDILL--LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRG------ 210
L + + L+ L VL L +N I +P ++ +L L ++N++ V
Sbjct: 623 NLKSIEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLC 682
Query: 211 ----VVDWRW----LLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS 260
+D + + P+I ++L+ +T NK+ LP ++ +KL TLK N +S
Sbjct: 683 NKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLS 742
Query: 261 RLPATIGRISTLRYFTISSNELQSLPCSLMQCR 293
L IG + L Y + N + LP L CR
Sbjct: 743 VLSPKIGNLLFLSYLDVKGNHFEILPPELGDCR 775
Score = 37.5 bits (83), Expect = 0.085
Identities = 35/125 (28%), Positives = 51/125 (40%), Gaps = 7/125 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L+ L S K+ + L + LDLS N+I +PPE G + +L + N+ V
Sbjct: 661 SLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNK--V 718
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ D + K LK L + N L L I L L L N LP +G
Sbjct: 719 ESLPDELY-----FCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPELGD 773
Query: 269 ISTLR 273
L+
Sbjct: 774 CRALK 778
>AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein.
Length = 803
Score = 54.8 bits (126), Expect = 5e-07
Identities = 37/139 (26%), Positives = 73/139 (52%), Gaps = 8/139 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GVRGVVDWRWLLGPQITKTLKL 228
+ +L L+L + ++E++P + +L EL L N L + +V ++ L + L +
Sbjct: 588 MTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHL------RKLTV 641
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L L N + ++P+ I KL L L + N I LP+ + + +RY +S N+++ +P
Sbjct: 642 LKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPE 701
Query: 289 L-MQCRLEYIDISSNKFDN 306
+ + L+Y I+ NK ++
Sbjct: 702 IGVLQSLQYFSITCNKVES 720
Score = 52.4 bits (120), Expect = 3e-06
Identities = 57/213 (26%), Positives = 94/213 (44%), Gaps = 24/213 (11%)
Query: 101 LLRSCITGD-EKALHLSPLSSLSVTAKNNAPVKLVISDRSQFP-AKGLPRTLQSLYLSGL 158
L + CI D K + L+ L ++ N ++LV D + P A +LQ L L
Sbjct: 567 LQKMCIHNDGTKLVMLNNLKKMT----NLTELELVHCDLERIPHAVFSLLSLQELDLKEN 622
Query: 159 KLCNFRRDILL--LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRG------ 210
L + + L+ L VL L +N I +P ++ +L L ++N++ V
Sbjct: 623 NLKSIEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLC 682
Query: 211 ----VVDWRW----LLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS 260
+D + + P+I ++L+ +T NK+ LP ++ +KL TLK N +S
Sbjct: 683 NKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLS 742
Query: 261 RLPATIGRISTLRYFTISSNELQSLPCSLMQCR 293
L IG + L Y + N + LP L CR
Sbjct: 743 VLSPKIGNLLFLSYLDVKGNHFEILPPELGDCR 775
Score = 37.5 bits (83), Expect = 0.085
Identities = 35/125 (28%), Positives = 51/125 (40%), Gaps = 7/125 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
+L+ L S K+ + L + LDLS N+I +PPE G + +L + N+ V
Sbjct: 661 SLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNK--V 718
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+ D + K LK L + N L L I L L L N LP +G
Sbjct: 719 ESLPDELY-----FCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPELGD 773
Query: 269 ISTLR 273
L+
Sbjct: 774 CRALK 778
>AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein.
Length = 802
Score = 54.4 bits (125), Expect = 7e-07
Identities = 45/159 (28%), Positives = 74/159 (46%), Gaps = 9/159 (5%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGV 208
L+SL L L I L +L LDL N ++ + F + NLS L L +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEISFQHLQNLSCLKLWHNNIAY 646
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 268
+G L+ L L N + +LP ++ KL L + N ++ +P I
Sbjct: 647 IPAQ-----IGA--LSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQY 699
Query: 269 ISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+S L+YF +++N ++ LP L QC +L+ + + N N
Sbjct: 700 LSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMN 738
Score = 40.3 bits (90), Expect = 0.012
Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 10/164 (6%)
Query: 126 KNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIE 184
+N + +KL ++ + PA+ G L+ L L + N + L L LDLS N +
Sbjct: 632 QNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLT 691
Query: 185 KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW 244
+P E ++NL + NN + + + D G K L+ L L N L +L +
Sbjct: 692 FIPEEIQYLSNLQYFAVTNNNIEM--LPD-----GLFQCKKLQCLLLGKNSLMNLSPHVG 744
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLR--YFTISSNELQSLP 286
+L L L+ N + LP + +L+ + N L +LP
Sbjct: 745 ELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLP 788
Score = 34.3 bits (75), Expect = 0.79
Identities = 36/137 (26%), Positives = 65/137 (47%), Gaps = 6/137 (4%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L ++L +L L E+ K+P + NL EL+L+ L + + L G Q K L+
Sbjct: 485 LEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQ--LSTMQLEGFQDLKNLRT 542
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA--TIGRISTLRYFTISSNELQSLP 286
L L S+ L +P+ + L + + DN S+L + ++ L+ + S +L+ +P
Sbjct: 543 LYLKSS-LSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIP 601
Query: 287 CSLMQC-RLEYIDISSN 302
S+ L +D+ N
Sbjct: 602 HSIFSLNNLHELDLREN 618
>D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein.
Length = 823
Score = 53.6 bits (123), Expect = 1e-06
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 10/160 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 207
L+SL L L I L +L LDL N ++ + F + NLS L L +N +
Sbjct: 607 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 666
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+G L+ L L N + +LP ++ KL L + N ++ +P I
Sbjct: 667 YIPAQ-----IGA--LSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQ 719
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+S L+YF +++N ++ LP L QC +L+ + + N N
Sbjct: 720 YLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMN 759
Score = 40.3 bits (90), Expect = 0.012
Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 10/164 (6%)
Query: 126 KNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIE 184
+N + +KL ++ + PA+ G L+ L L + N + L L LDLS N +
Sbjct: 653 QNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLT 712
Query: 185 KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW 244
+P E ++NL + NN + + + D G K L+ L L N L +L +
Sbjct: 713 FIPEEIQYLSNLQYFAVTNNNIEM--LPD-----GLFQCKKLQCLLLGKNSLMNLSPHVG 765
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLR--YFTISSNELQSLP 286
+L L L+ N + LP + +L+ + N L +LP
Sbjct: 766 ELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLP 809
Score = 34.3 bits (75), Expect = 0.79
Identities = 36/137 (26%), Positives = 65/137 (47%), Gaps = 6/137 (4%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L ++L +L L E+ K+P + NL EL+L+ L + + L G Q K L+
Sbjct: 505 LEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQ--LSTMQLEGFQDLKNLRT 562
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA--TIGRISTLRYFTISSNELQSLP 286
L L S+ L +P+ + L + + DN S+L + ++ L+ + S +L+ +P
Sbjct: 563 LYLKSS-LSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIP 621
Query: 287 CSLMQC-RLEYIDISSN 302
S+ L +D+ N
Sbjct: 622 HSIFSLNNLHELDLREN 638
>BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein.
Length = 532
Score = 53.6 bits (123), Expect = 1e-06
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 7/145 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L +L L ++ + L+ L L LS N++E LP + G + L L +++N G
Sbjct: 366 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHN--G 423
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + LL + L+ L L+ N L LP+ ++ KL TL DN +S+L +G
Sbjct: 424 LHSLPPEVGLL-----QNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVG 478
Query: 268 RISTLRYFTISSNELQSLPCSLMQC 292
+ L + N L++LP L C
Sbjct: 479 ALRALSRLELKGNRLEALPEELGNC 503
Score = 52.8 bits (121), Expect = 2e-06
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 211
SL+ G +L + L L L+L +E++P + L EL L +N L R +
Sbjct: 300 SLHNDGARLVALN-SLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHL--RSI 356
Query: 212 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ +L Q + L L L N++ ++P+ + KL L L + N + LP+ +G S
Sbjct: 357 EE---ILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSG 413
Query: 272 LRYFTISSNELQSLP--CSLMQCRLEYIDISSNKFD 305
LR +S N L SLP L+Q L+++ +S N +
Sbjct: 414 LRLLDVSHNGLHSLPPEVGLLQ-NLQHLALSYNALE 448
Score = 52.0 bits (119), Expect = 4e-06
Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 7/126 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ LYLS KL + L L +LD+S+N + LPPE G + NL L L+ N L
Sbjct: 389 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNAL- 447
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + + L+ L L N+L L + L L L+ N + LP +G
Sbjct: 448 -EALPEELF-----FCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 501
Query: 268 RISTLR 273
L+
Sbjct: 502 NCGGLK 507
Score = 42.7 bits (96), Expect = 0.002
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 207
L+ L L L + L L LDL +N + + F L L L +NQ+
Sbjct: 320 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 379
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V + L ++L+ L L+ NKL LP + L L + N + LP +G
Sbjct: 380 Y--VPEHVRKL-----RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVG 432
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR 293
+ L++ +S N L++LP L CR
Sbjct: 433 LLQNLQHLALSYNALEALPEELFFCR 458
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/126 (30%), Positives = 55/126 (43%), Gaps = 13/126 (10%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL L+ L +S L + ++ LL++L L LS N +E LP E L L L +N
Sbjct: 409 GLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDN 468
Query: 205 QLGVRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLE--KLVTLKANDNMIS 260
QL L P + + L L+L N+L LP+ + K L D +
Sbjct: 469 QLS---------QLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQ 519
Query: 261 RLPATI 266
LPA +
Sbjct: 520 GLPAEV 525
Score = 31.5 bits (68), Expect = 5.6
Identities = 34/143 (23%), Positives = 66/143 (46%), Gaps = 6/143 (4%)
Query: 163 FRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI 222
F + L HL V+ + E+ ++P + L ELHL L + + L +
Sbjct: 212 FSLQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEG--LFPQELARAATLESLRE 269
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA--TIGRISTLRYFTISSN 280
K LK+L L SN G +P ++ + + + N +RL A ++ +++ LR + +
Sbjct: 270 LKQLKVLSLRSN-AGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELELVAC 328
Query: 281 ELQSLPCSLMQC-RLEYIDISSN 302
L+ +P ++ L+ +D+ N
Sbjct: 329 GLERIPHAVFSLGALQELDLKDN 351
>BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat
containing 8 family, member E protein.
Length = 796
Score = 53.6 bits (123), Expect = 1e-06
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 7/145 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L +L L ++ + L+ L L LS N++E LP + G + L L +++N G
Sbjct: 630 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHN--G 687
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + LL + L+ L L+ N L LP+ ++ KL TL DN +S+L +G
Sbjct: 688 LHSLPPEVGLL-----QNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVG 742
Query: 268 RISTLRYFTISSNELQSLPCSLMQC 292
+ L + N L++LP L C
Sbjct: 743 ALRALSRLELKGNRLEALPEELGNC 767
Score = 52.8 bits (121), Expect = 2e-06
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 211
SL+ G +L + L L L+L +E++P + L EL L +N L R +
Sbjct: 564 SLHNDGARLVALN-SLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHL--RSI 620
Query: 212 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ +L Q + L L L N++ ++P+ + KL L L + N + LP+ +G S
Sbjct: 621 EE---ILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSG 677
Query: 272 LRYFTISSNELQSLP--CSLMQCRLEYIDISSNKFD 305
LR +S N L SLP L+Q L+++ +S N +
Sbjct: 678 LRLLDVSHNGLHSLPPEVGLLQ-NLQHLALSYNALE 712
Score = 52.0 bits (119), Expect = 4e-06
Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 7/126 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ LYLS KL + L L +LD+S+N + LPPE G + NL L L+ N L
Sbjct: 653 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNAL- 711
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + + L+ L L N+L L + L L L+ N + LP +G
Sbjct: 712 -EALPEELF-----FCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 765
Query: 268 RISTLR 273
L+
Sbjct: 766 NCGGLK 771
Score = 42.7 bits (96), Expect = 0.002
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 207
L+ L L L + L L LDL +N + + F L L L +NQ+
Sbjct: 584 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 643
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V + L ++L+ L L+ NKL LP + L L + N + LP +G
Sbjct: 644 Y--VPEHVRKL-----RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVG 696
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR 293
+ L++ +S N L++LP L CR
Sbjct: 697 LLQNLQHLALSYNALEALPEELFFCR 722
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/126 (30%), Positives = 55/126 (43%), Gaps = 13/126 (10%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL L+ L +S L + ++ LL++L L LS N +E LP E L L L +N
Sbjct: 673 GLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDN 732
Query: 205 QLGVRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLE--KLVTLKANDNMIS 260
QL L P + + L L+L N+L LP+ + K L D +
Sbjct: 733 QLS---------QLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQ 783
Query: 261 RLPATI 266
LPA +
Sbjct: 784 GLPAEV 789
Score = 31.5 bits (68), Expect = 5.6
Identities = 34/143 (23%), Positives = 66/143 (46%), Gaps = 6/143 (4%)
Query: 163 FRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI 222
F + L HL V+ + E+ ++P + L ELHL L + + L +
Sbjct: 476 FSLQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEG--LFPQELARAATLESLRE 533
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA--TIGRISTLRYFTISSN 280
K LK+L L SN G +P ++ + + + N +RL A ++ +++ LR + +
Sbjct: 534 LKQLKVLSLRSN-AGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELELVAC 592
Query: 281 ELQSLPCSLMQC-RLEYIDISSN 302
L+ +P ++ L+ +D+ N
Sbjct: 593 GLERIPHAVFSLGALQELDLKDN 615
>BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein.
Length = 803
Score = 53.6 bits (123), Expect = 1e-06
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 10/160 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 207
L+SL L L I L +L LDL N ++ + F + NLS L L +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 646
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+G L+ L L N + +LP ++ KL L + N ++ +P I
Sbjct: 647 YIPAQ-----IGA--LSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQ 699
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+S L+YF +++N ++ LP L QC +L+ + + N N
Sbjct: 700 YLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMN 739
Score = 40.3 bits (90), Expect = 0.012
Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 10/164 (6%)
Query: 126 KNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIE 184
+N + +KL ++ + PA+ G L+ L L + N + L L LDLS N +
Sbjct: 633 QNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLT 692
Query: 185 KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW 244
+P E ++NL + NN + + + D G K L+ L L N L +L +
Sbjct: 693 FIPEEIQYLSNLQYFAVTNNNIEM--LPD-----GLFQCKKLQCLLLGKNSLMNLSPHVG 745
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLR--YFTISSNELQSLP 286
+L L L+ N + LP + +L+ + N L +LP
Sbjct: 746 ELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLP 789
Score = 34.3 bits (75), Expect = 0.79
Identities = 36/137 (26%), Positives = 65/137 (47%), Gaps = 6/137 (4%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L ++L +L L E+ K+P + NL EL+L+ L + + L G Q K L+
Sbjct: 485 LEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQ--LSTMQLEGFQDLKNLRT 542
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA--TIGRISTLRYFTISSNELQSLP 286
L L S+ L +P+ + L + + DN S+L + ++ L+ + S +L+ +P
Sbjct: 543 LYLKSS-LSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIP 601
Query: 287 CSLMQC-RLEYIDISSN 302
S+ L +D+ N
Sbjct: 602 HSIFSLNNLHELDLREN 618
>BC036722-1|AAH36722.1| 261|Homo sapiens leucine rich repeat
containing 18 protein.
Length = 261
Score = 53.6 bits (123), Expect = 1e-06
Identities = 32/111 (28%), Positives = 63/111 (56%), Gaps = 7/111 (6%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLKLL 229
++L LDL +N I+KLP G+M +L L+++NN+L G+ V+ + L K ++ +
Sbjct: 73 QNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQL------KNIRAV 126
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 280
+L N L + + L++L + +DN+++ +P +I ++ L+ I N
Sbjct: 127 NLGLNHLDSVSTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRN 177
Score = 49.6 bits (113), Expect = 2e-05
Identities = 27/81 (33%), Positives = 47/81 (58%), Gaps = 3/81 (3%)
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS--LP 286
LDL+ N + +P +I K + L L + N I +LP +IG++++L Y +S+N L S LP
Sbjct: 55 LDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLP 114
Query: 287 CSLMQCR-LEYIDISSNKFDN 306
L Q + + +++ N D+
Sbjct: 115 VELKQLKNIRAVNLGLNHLDS 135
Score = 47.6 bits (108), Expect = 8e-05
Identities = 42/155 (27%), Positives = 76/155 (49%), Gaps = 10/155 (6%)
Query: 153 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 212
L LS + + F + IL L + LDLS N I K+P + NL L L +N +
Sbjct: 32 LDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYID----- 86
Query: 213 DWRWLLGPQITKTLKLLDLTSNKL--GHLPKAIWKLEKLVTLKANDNMISRLPATIGRIS 270
+G Q+T +L L++++N+L LP + +L+ + + N + + T+G +
Sbjct: 87 KLPESIG-QMT-SLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVSTTLGALK 144
Query: 271 TLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKF 304
L + N L ++P S+ + +L+ ++I N F
Sbjct: 145 ELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPF 179
Score = 47.2 bits (107), Expect = 1e-04
Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Query: 227 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 286
K LDL+ + PK I +L + L + N+I ++P +I + LR+ + SN + LP
Sbjct: 30 KRLDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLP 89
Query: 287 CSLMQ-CRLEYIDISSNK 303
S+ Q L Y+++S+N+
Sbjct: 90 ESIGQMTSLLYLNVSNNR 107
>BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat
containing 8 family, member B protein.
Length = 803
Score = 53.6 bits (123), Expect = 1e-06
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 10/160 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 207
L+SL L L I L +L LDL N ++ + F + NLS L L +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 646
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+G L+ L L N + +LP ++ KL L + N ++ +P I
Sbjct: 647 YIPAQ-----IGA--LSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQ 699
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+S L+YF +++N ++ LP L QC +L+ + + N N
Sbjct: 700 YLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMN 739
Score = 40.3 bits (90), Expect = 0.012
Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 10/164 (6%)
Query: 126 KNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIE 184
+N + +KL ++ + PA+ G L+ L L + N + L L LDLS N +
Sbjct: 633 QNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLT 692
Query: 185 KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW 244
+P E ++NL + NN + + + D G K L+ L L N L +L +
Sbjct: 693 FIPEEIQYLSNLQYFAVTNNNIEM--LPD-----GLFQCKKLQCLLLGKNSLMNLSPHVG 745
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLR--YFTISSNELQSLP 286
+L L L+ N + LP + +L+ + N L +LP
Sbjct: 746 ELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLP 789
Score = 34.3 bits (75), Expect = 0.79
Identities = 36/137 (26%), Positives = 65/137 (47%), Gaps = 6/137 (4%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L ++L +L L E+ K+P + NL EL+L+ L + + L G Q K L+
Sbjct: 485 LEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQ--LSTMQLEGFQDLKNLRT 542
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA--TIGRISTLRYFTISSNELQSLP 286
L L S+ L +P+ + L + + DN S+L + ++ L+ + S +L+ +P
Sbjct: 543 LYLKSS-LSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIP 601
Query: 287 CSLMQC-RLEYIDISSN 302
S+ L +D+ N
Sbjct: 602 HSIFSLNNLHELDLREN 618
>BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein.
Length = 592
Score = 53.6 bits (123), Expect = 1e-06
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 7/145 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L +L L ++ + L+ L L LS N++E LP + G + L L +++N G
Sbjct: 426 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHN--G 483
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + LL + L+ L L+ N L LP+ ++ KL TL DN +S+L +G
Sbjct: 484 LHSLPPEVGLL-----QNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVG 538
Query: 268 RISTLRYFTISSNELQSLPCSLMQC 292
+ L + N L++LP L C
Sbjct: 539 ALRALSRLELKGNRLEALPEELGNC 563
Score = 52.8 bits (121), Expect = 2e-06
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 211
SL+ G +L + L L L+L +E++P + L EL L +N L R +
Sbjct: 360 SLHNDGARLVALN-SLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHL--RSI 416
Query: 212 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ +L Q + L L L N++ ++P+ + KL L L + N + LP+ +G S
Sbjct: 417 EE---ILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSG 473
Query: 272 LRYFTISSNELQSLP--CSLMQCRLEYIDISSNKFD 305
LR +S N L SLP L+Q L+++ +S N +
Sbjct: 474 LRLLDVSHNGLHSLPPEVGLLQ-NLQHLALSYNALE 508
Score = 52.0 bits (119), Expect = 4e-06
Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 7/126 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ LYLS KL + L L +LD+S+N + LPPE G + NL L L+ N L
Sbjct: 449 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNAL- 507
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + + L+ L L N+L L + L L L+ N + LP +G
Sbjct: 508 -EALPEELF-----FCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 561
Query: 268 RISTLR 273
L+
Sbjct: 562 NCGGLK 567
Score = 42.7 bits (96), Expect = 0.002
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 207
L+ L L L + L L LDL +N + + F L L L +NQ+
Sbjct: 380 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 439
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V + L ++L+ L L+ NKL LP + L L + N + LP +G
Sbjct: 440 Y--VPEHVRKL-----RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVG 492
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR 293
+ L++ +S N L++LP L CR
Sbjct: 493 LLQNLQHLALSYNALEALPEELFFCR 518
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/126 (30%), Positives = 55/126 (43%), Gaps = 13/126 (10%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL L+ L +S L + ++ LL++L L LS N +E LP E L L L +N
Sbjct: 469 GLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDN 528
Query: 205 QLGVRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLE--KLVTLKANDNMIS 260
QL L P + + L L+L N+L LP+ + K L D +
Sbjct: 529 QLS---------QLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQ 579
Query: 261 RLPATI 266
LPA +
Sbjct: 580 GLPAEV 585
Score = 31.5 bits (68), Expect = 5.6
Identities = 34/143 (23%), Positives = 66/143 (46%), Gaps = 6/143 (4%)
Query: 163 FRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI 222
F + L HL V+ + E+ ++P + L ELHL L + + L +
Sbjct: 272 FSLQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEG--LFPQELARAATLESLRE 329
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA--TIGRISTLRYFTISSN 280
K LK+L L SN G +P ++ + + + N +RL A ++ +++ LR + +
Sbjct: 330 LKQLKVLSLRSN-AGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELELVAC 388
Query: 281 ELQSLPCSLMQC-RLEYIDISSN 302
L+ +P ++ L+ +D+ N
Sbjct: 389 GLERIPHAVFSLGALQELDLKDN 411
>AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein
protein.
Length = 622
Score = 53.6 bits (123), Expect = 1e-06
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 7/145 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L +L L ++ + L+ L L LS N++E LP + G + L L +++N G
Sbjct: 456 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHN--G 513
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + LL + L+ L L+ N L LP+ ++ KL TL DN +S+L +G
Sbjct: 514 LHSLPPEVGLL-----QNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVG 568
Query: 268 RISTLRYFTISSNELQSLPCSLMQC 292
+ L + N L++LP L C
Sbjct: 569 ALRALSRLELKGNRLEALPEELGNC 593
Score = 52.8 bits (121), Expect = 2e-06
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 211
SL+ G +L + L L L+L +E++P + L EL L +N L R +
Sbjct: 390 SLHNDGARLVALN-SLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHL--RSI 446
Query: 212 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ +L Q + L L L N++ ++P+ + KL L L + N + LP+ +G S
Sbjct: 447 EE---ILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSG 503
Query: 272 LRYFTISSNELQSLP--CSLMQCRLEYIDISSNKFD 305
LR +S N L SLP L+Q L+++ +S N +
Sbjct: 504 LRLLDVSHNGLHSLPPEVGLLQ-NLQHLALSYNALE 538
Score = 52.0 bits (119), Expect = 4e-06
Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 7/126 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ LYLS KL + L L +LD+S+N + LPPE G + NL L L+ N L
Sbjct: 479 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNAL- 537
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + + L+ L L N+L L + L L L+ N + LP +G
Sbjct: 538 -EALPEELF-----FCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 591
Query: 268 RISTLR 273
L+
Sbjct: 592 NCGGLK 597
Score = 42.7 bits (96), Expect = 0.002
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 207
L+ L L L + L L LDL +N + + F L L L +NQ+
Sbjct: 410 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 469
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V + L ++L+ L L+ NKL LP + L L + N + LP +G
Sbjct: 470 Y--VPEHVRKL-----RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVG 522
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR 293
+ L++ +S N L++LP L CR
Sbjct: 523 LLQNLQHLALSYNALEALPEELFFCR 548
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/126 (30%), Positives = 55/126 (43%), Gaps = 13/126 (10%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL L+ L +S L + ++ LL++L L LS N +E LP E L L L +N
Sbjct: 499 GLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDN 558
Query: 205 QLGVRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLE--KLVTLKANDNMIS 260
QL L P + + L L+L N+L LP+ + K L D +
Sbjct: 559 QLS---------QLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQ 609
Query: 261 RLPATI 266
LPA +
Sbjct: 610 GLPAEV 615
Score = 31.5 bits (68), Expect = 5.6
Identities = 34/143 (23%), Positives = 66/143 (46%), Gaps = 6/143 (4%)
Query: 163 FRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI 222
F + L HL V+ + E+ ++P + L ELHL L + + L +
Sbjct: 302 FSLQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEG--LFPQELARAATLESLRE 359
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA--TIGRISTLRYFTISSN 280
K LK+L L SN G +P ++ + + + N +RL A ++ +++ LR + +
Sbjct: 360 LKQLKVLSLRSN-AGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELELVAC 418
Query: 281 ELQSLPCSLMQC-RLEYIDISSN 302
L+ +P ++ L+ +D+ N
Sbjct: 419 GLERIPHAVFSLGALQELDLKDN 441
>AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens
cDNA: FLJ23420 fis, clone HEP22352. ).
Length = 444
Score = 53.6 bits (123), Expect = 1e-06
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 7/145 (4%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R L +L L ++ + L+ L L LS N++E LP + G + L L +++N G
Sbjct: 278 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHN--G 335
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + LL + L+ L L+ N L LP+ ++ KL TL DN +S+L +G
Sbjct: 336 LHSLPPEVGLL-----QNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVG 390
Query: 268 RISTLRYFTISSNELQSLPCSLMQC 292
+ L + N L++LP L C
Sbjct: 391 ALRALSRLELKGNRLEALPEELGNC 415
Score = 52.8 bits (121), Expect = 2e-06
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 211
SL+ G +L + L L L+L +E++P + L EL L +N L R +
Sbjct: 212 SLHNDGARLVALN-SLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHL--RSI 268
Query: 212 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
+ +L Q + L L L N++ ++P+ + KL L L + N + LP+ +G S
Sbjct: 269 EE---ILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSG 325
Query: 272 LRYFTISSNELQSLP--CSLMQCRLEYIDISSNKFD 305
LR +S N L SLP L+Q L+++ +S N +
Sbjct: 326 LRLLDVSHNGLHSLPPEVGLLQ-NLQHLALSYNALE 360
Score = 52.0 bits (119), Expect = 4e-06
Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 7/126 (5%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
R+L+ LYLS KL + L L +LD+S+N + LPPE G + NL L L+ N L
Sbjct: 301 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNAL- 359
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+ + + + L+ L L N+L L + L L L+ N + LP +G
Sbjct: 360 -EALPEELF-----FCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 413
Query: 268 RISTLR 273
L+
Sbjct: 414 NCGGLK 419
Score = 42.7 bits (96), Expect = 0.002
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 207
L+ L L L + L L LDL +N + + F L L L +NQ+
Sbjct: 232 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 291
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
V + L ++L+ L L+ NKL LP + L L + N + LP +G
Sbjct: 292 Y--VPEHVRKL-----RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVG 344
Query: 268 RISTLRYFTISSNELQSLPCSLMQCR 293
+ L++ +S N L++LP L CR
Sbjct: 345 LLQNLQHLALSYNALEALPEELFFCR 370
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/126 (30%), Positives = 55/126 (43%), Gaps = 13/126 (10%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL L+ L +S L + ++ LL++L L LS N +E LP E L L L +N
Sbjct: 321 GLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDN 380
Query: 205 QLGVRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLE--KLVTLKANDNMIS 260
QL L P + + L L+L N+L LP+ + K L D +
Sbjct: 381 QLS---------QLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQ 431
Query: 261 RLPATI 266
LPA +
Sbjct: 432 GLPAEV 437
Score = 31.5 bits (68), Expect = 5.6
Identities = 34/143 (23%), Positives = 66/143 (46%), Gaps = 6/143 (4%)
Query: 163 FRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI 222
F + L HL V+ + E+ ++P + L ELHL L + + L +
Sbjct: 124 FSLQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEG--LFPQELARAATLESLRE 181
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA--TIGRISTLRYFTISSN 280
K LK+L L SN G +P ++ + + + N +RL A ++ +++ LR + +
Sbjct: 182 LKQLKVLSLRSN-AGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELELVAC 240
Query: 281 ELQSLPCSLMQC-RLEYIDISSN 302
L+ +P ++ L+ +D+ N
Sbjct: 241 GLERIPHAVFSLGALQELDLKDN 263
>AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens
cDNA FLJ20331 fis, clone HEP10410. ).
Length = 384
Score = 53.6 bits (123), Expect = 1e-06
Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 9/134 (6%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
+K L LD ++N +E +PPE M +L L+L N+L R+L LK L
Sbjct: 1 MKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL--------RFLPEFPSCSLLKEL 52
Query: 230 DLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
+ N++ L K L ++ L DN + +P I + +L +S+N++ SLP S
Sbjct: 53 HVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYS 112
Query: 289 LMQCRLEYIDISSN 302
L L+++ + N
Sbjct: 113 LGNLHLKFLALEGN 126
Score = 48.4 bits (110), Expect = 5e-05
Identities = 35/136 (25%), Positives = 66/136 (48%), Gaps = 8/136 (5%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 205
L + + LS KL ++ +L+ L LDL NN + LP E + L ++L+ N+
Sbjct: 229 LKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNR 288
Query: 206 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPA 264
+ V +R TL+ + +++N++G + P+ + +E L TL +N + ++P
Sbjct: 289 FKMLPEVLYRIF-------TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPP 341
Query: 265 TIGRISTLRYFTISSN 280
+G LR + N
Sbjct: 342 ELGNCVNLRTLLLDGN 357
Score = 42.3 bits (95), Expect = 0.003
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 222 ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNE 281
+ + L LDL +N L LP+ + L +L T+ + N LP + RI TL IS+N+
Sbjct: 252 VLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 311
Query: 282 LQSLPCSLMQC--RLEYIDISSN 302
+ S+ M+ L +D+ +N
Sbjct: 312 VGSVDPQKMKMMENLTTLDLQNN 334
Score = 37.9 bits (84), Expect = 0.064
Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query: 173 LAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L +LD S+ + +P E F + + ++ ++ + NQL + R + ++ + + +
Sbjct: 183 LKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCE---IPKRMV---ELKEMVSDV 236
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
DL+ NKL + + L+KL L +N ++ LP + + L+ +S N + LP L
Sbjct: 237 DLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL 296
Query: 290 MQC-RLEYIDISSNK 303
+ LE I IS+N+
Sbjct: 297 YRIFTLETILISNNQ 311
Score = 37.5 bits (83), Expect = 0.085
Identities = 36/158 (22%), Positives = 74/158 (46%), Gaps = 14/158 (8%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAV-LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRG 210
S+ S +LC + ++ LK + +DLS N++ + E + L+ L L NN L
Sbjct: 211 SINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLN--- 267
Query: 211 VVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIG 267
L ++ ++L ++L+ N+ LP+ ++++ L T+ ++N + + P +
Sbjct: 268 ------SLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMK 321
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKF 304
+ L + +N+L +P L C L + + N F
Sbjct: 322 MMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPF 359
Score = 37.5 bits (83), Expect = 0.085
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 149 TLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 207
TL+++ +S ++ + + + ++++L LDL NN++ ++PPE G NL L L N
Sbjct: 301 TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFR 360
Query: 208 V 208
V
Sbjct: 361 V 361
Score = 34.7 bits (76), Expect = 0.60
Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 159 KLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
KL + +I+LL+ L LDLSNN+I LP G + +L L L N L
Sbjct: 82 KLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKFLALEGNPL 128
>AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leucine
repeat-rich protein protein.
Length = 803
Score = 53.6 bits (123), Expect = 1e-06
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 10/160 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 207
L+SL L L I L +L LDL N ++ + F + NLS L L +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 646
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 267
+G L+ L L N + +LP ++ KL L + N ++ +P I
Sbjct: 647 YIPAQ-----IGA--LSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQ 699
Query: 268 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
+S L+YF +++N ++ LP L QC +L+ + + N N
Sbjct: 700 YLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMN 739
Score = 40.3 bits (90), Expect = 0.012
Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 10/164 (6%)
Query: 126 KNNAPVKLVISDRSQFPAK-GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIE 184
+N + +KL ++ + PA+ G L+ L L + N + L L LDLS N +
Sbjct: 633 QNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLT 692
Query: 185 KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW 244
+P E ++NL + NN + + + D G K L+ L L N L +L +
Sbjct: 693 FIPEEIQYLSNLQYFAVTNNNIEM--LPD-----GLFQCKKLQCLLLGKNSLMNLSPHVG 745
Query: 245 KLEKLVTLKANDNMISRLPATIGRISTLR--YFTISSNELQSLP 286
+L L L+ N + LP + +L+ + N L +LP
Sbjct: 746 ELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLP 789
Score = 34.3 bits (75), Expect = 0.79
Identities = 36/137 (26%), Positives = 65/137 (47%), Gaps = 6/137 (4%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L ++L +L L E+ K+P + NL EL+L+ L + + L G Q K L+
Sbjct: 485 LEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQ--LSTMQLEGFQDLKNLRT 542
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA--TIGRISTLRYFTISSNELQSLP 286
L L S+ L +P+ + L + + DN S+L + ++ L+ + S +L+ +P
Sbjct: 543 LYLKSS-LSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIP 601
Query: 287 CSLMQC-RLEYIDISSN 302
S+ L +D+ N
Sbjct: 602 HSIFSLNNLHELDLREN 618
>AB033020-1|BAA86508.1| 575|Homo sapiens KIAA1194 protein protein.
Length = 575
Score = 53.6 bits (123), Expect = 1e-06
Identities = 29/59 (49%), Positives = 35/59 (59%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
L +L+LS L DI L +L LDLS+N+I LP E G M +L ELHL NN L V
Sbjct: 71 LTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRV 129
Score = 50.8 bits (116), Expect = 9e-06
Identities = 22/57 (38%), Positives = 35/57 (61%)
Query: 233 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
S K+ L ++W L L L +DN +SR+P+ I ++ L Y +SSN+++SLP L
Sbjct: 55 SGKVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAEL 111
Score = 43.2 bits (97), Expect = 0.002
Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 8/111 (7%)
Query: 172 HLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 231
H A L++S ++ L + +L+ LHL++N L R D L L LDL
Sbjct: 48 HWAELEISG-KVRSLSASLWSLTHLTALHLSDNSLS-RIPSDIAKL------HNLVYLDL 99
Query: 232 TSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
+SNK+ LP + + L L N+N++ LP +G++ L+ + N L
Sbjct: 100 SSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNPL 150
Score = 41.5 bits (93), Expect = 0.005
Identities = 36/123 (29%), Positives = 62/123 (50%), Gaps = 8/123 (6%)
Query: 139 SQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSE 198
S+ A G L +SG K+ + + L HL L LS+N + ++P + ++ NL
Sbjct: 38 SEEAANGKKSHWAELEISG-KVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVY 96
Query: 199 LHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM 258
L L++N+ +R + LG + +L+ L L +N L LP + KL +L TL N
Sbjct: 97 LDLSSNK--IRSLPA---ELGNMV--SLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNP 149
Query: 259 ISR 261
+++
Sbjct: 150 LTQ 152
>BC007504-1|AAH07504.1| 712|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 3 protein.
Length = 712
Score = 53.2 bits (122), Expect = 2e-06
Identities = 50/168 (29%), Positives = 74/168 (44%), Gaps = 17/168 (10%)
Query: 153 LYLSGLKLCNFRRDILL--LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV-- 208
L LSG KL F R L DLS N + ++P E +L L+L N +
Sbjct: 62 LSLSGRKLREFPRGAANHDLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIP 121
Query: 209 RGVVDWRWLLGPQITKT-------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKAN 255
+++ + L I++ LK+L ++NKL LP+ I L L+ L +
Sbjct: 122 EAILNLQALTFLNISRNQLSTLPVHLCNLPLKVLIASNNKLVSLPEEIGHLRHLMELDVS 181
Query: 256 DNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
N I +P+ IG + LR + N L LP L + L +D S NK
Sbjct: 182 CNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELPLIRLDFSCNK 229
Score = 48.4 bits (110), Expect = 5e-05
Identities = 39/135 (28%), Positives = 64/135 (47%), Gaps = 15/135 (11%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L S KL + +I L+HL LD+S NEI+ +P + G + L +L++ N L
Sbjct: 152 LKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHL--- 208
Query: 210 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 266
+ P+ L L LD + NK+ +P L L T+ ++N + PA I
Sbjct: 209 -------VHLPEELAELPLIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQIC 261
Query: 267 --GRISTLRYFTISS 279
G++ +Y I +
Sbjct: 262 IKGKVHIFKYLNIQA 276
>BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like family,
member 4 protein.
Length = 837
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/121 (32%), Positives = 61/121 (50%), Gaps = 8/121 (6%)
Query: 168 LLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
L H L L NN+++ + F ++ L +LHL NN+L + + LG + L
Sbjct: 80 LNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTF---LG---IENL 133
Query: 227 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
+ L N + ++ + + KL KL L NDN+IS LP I R ++L + I N +Q L
Sbjct: 134 EYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKL 193
Query: 286 P 286
P
Sbjct: 194 P 194
Score = 30.7 bits (66), Expect = 9.8
Identities = 42/168 (25%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 147 PRTLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANN 204
P + L+++G + + D + L +L L +N+I + + F + NL L+L N
Sbjct: 376 PLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGN 435
Query: 205 QLGVRGVVDWRWLLGPQITK---TLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMIS 260
Q+ L P+I L+ L L N + + + + L L N+N++
Sbjct: 436 QIE---------RLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLK 486
Query: 261 RLPATIGRISTLRYFTISSNELQSLPCS--LMQCR-LEYIDISSNKFD 305
LP I + L + +N+ LP S L Q + L ID+ N +D
Sbjct: 487 SLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWD 534
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 9/116 (7%)
Query: 174 AVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 232
A LDLS N + +L P F + L EL L+ N L + + G +LK+L L
Sbjct: 69 AYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILMLQ 122
Query: 233 SNKLGHLP-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 286
+N+LG +P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 123 NNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 178
Score = 45.2 bits (102), Expect = 4e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 351 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 403
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 273
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 404 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 449
Score = 38.7 bits (86), Expect = 0.037
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L + L+ N I +P F + +L LHL NN++ G + L L+
Sbjct: 185 LPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL------HNLET 238
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 263
LDL NKL P AI L +L L ++N I +P
Sbjct: 239 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 273
Score = 34.3 bits (75), Expect = 0.79
Identities = 47/158 (29%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMAN--LSELHLANNQLG 207
L++L L+ KL F I L L L NN I+ +P E M N L +H +N +
Sbjct: 236 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP-EKAFMGNPLLQTIHFYDNPIQ 294
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 266
G +++L P++ TL L + K LE L +A I LP+ +
Sbjct: 295 FVGRSAFQYL--PKL-HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAG---IRLLPSGMC 348
Query: 267 GRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
++ LR +S N+++ LP SL +C +LE I + N+
Sbjct: 349 QQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGLQHNR 385
>AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein.
Length = 837
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/121 (32%), Positives = 61/121 (50%), Gaps = 8/121 (6%)
Query: 168 LLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
L H L L NN+++ + F ++ L +LHL NN+L + + LG + L
Sbjct: 80 LNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTF---LG---IENL 133
Query: 227 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
+ L N + ++ + + KL KL L NDN+IS LP I R ++L + I N +Q L
Sbjct: 134 EYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKL 193
Query: 286 P 286
P
Sbjct: 194 P 194
Score = 30.7 bits (66), Expect = 9.8
Identities = 42/168 (25%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 147 PRTLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANN 204
P + L+++G + + D + L +L L +N+I + + F + NL L+L N
Sbjct: 376 PLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGN 435
Query: 205 QLGVRGVVDWRWLLGPQITK---TLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMIS 260
Q+ L P+I L+ L L N + + + + L L N+N++
Sbjct: 436 QIE---------RLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLK 486
Query: 261 RLPATIGRISTLRYFTISSNELQSLPCS--LMQCR-LEYIDISSNKFD 305
LP I + L + +N+ LP S L Q + L ID+ N +D
Sbjct: 487 SLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWD 534
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 52.8 bits (121), Expect = 2e-06
Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 9/116 (7%)
Query: 174 AVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 232
A LDLS N + +L P F + L EL L+ N L + + G +LK+L L
Sbjct: 30 AYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILMLQ 83
Query: 233 SNKLGHLP-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 286
+N+LG +P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 84 NNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 139
Score = 45.2 bits (102), Expect = 4e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 312 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 364
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 273
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 365 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 410
Score = 38.7 bits (86), Expect = 0.037
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L + L+ N I +P F + +L LHL NN++ G + L L+
Sbjct: 146 LPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL------HNLET 199
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 263
LDL NKL P AI L +L L ++N I +P
Sbjct: 200 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 234
Score = 34.3 bits (75), Expect = 0.79
Identities = 47/158 (29%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMAN--LSELHLANNQLG 207
L++L L+ KL F I L L L NN I+ +P E M N L +H +N +
Sbjct: 197 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP-EKAFMGNPLLQTIHFYDNPIQ 255
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 266
G +++L P++ TL L + K LE L +A I LP+ +
Sbjct: 256 FVGRSAFQYL--PKL-HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAG---IRLLPSGMC 309
Query: 267 GRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
++ LR +S N+++ LP SL +C +LE I + N+
Sbjct: 310 QQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGLQHNR 346
>BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein.
Length = 748
Score = 52.0 bits (119), Expect = 4e-06
Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 11/133 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S KL + +I LK L LD+S NEI+ LP + G++ +L EL++ N L V
Sbjct: 181 LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHV- 239
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI--- 266
+ D LG L LD + NK+ +P KL L + ++N + PA I
Sbjct: 240 -LPD---ELG---DLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLK 292
Query: 267 GRISTLRYFTISS 279
G++ +Y I +
Sbjct: 293 GKVHIFKYLNIQA 305
Score = 50.4 bits (115), Expect = 1e-05
Identities = 42/137 (30%), Positives = 66/137 (48%), Gaps = 14/137 (10%)
Query: 153 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 212
L LSG KL +F L DLS N ++P + A L L+L +N +
Sbjct: 93 LSLSGRKLRDFPGSGYDLTDTTQADLSRNRFTEIPSDVWLFAPLETLNLYHNCIKTI--- 149
Query: 213 DWRWLLGPQITKTLKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 269
P+ K L++L +++ N L LPK ++ L V + +N+ ++S +P IG++
Sbjct: 150 -------PEAIKNLQMLTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVS-IPEEIGKL 201
Query: 270 STLRYFTISSNELQSLP 286
L IS NE+Q LP
Sbjct: 202 KDLMELDISCNEIQVLP 218
Score = 50.4 bits (115), Expect = 1e-05
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 219 GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTIS 278
G +T T + DL+ N+ +P +W L TL N I +P I + L Y IS
Sbjct: 107 GYDLTDTTQA-DLSRNRFTEIPSDVWLFAPLETLNLYHNCIKTIPEAIKNLQMLTYLNIS 165
Query: 279 SNELQSLPCSLMQCRLEYIDISSNK 303
N L +LP L L+ + +S+NK
Sbjct: 166 RNLLSTLPKYLFDLPLKVLVVSNNK 190
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 52.0 bits (119), Expect = 4e-06
Identities = 41/139 (29%), Positives = 66/139 (47%), Gaps = 9/139 (6%)
Query: 104 SCITGDEKALHLSPLSSLSVTAKNNAPVKLVISDRSQFPAKGLPRTLQSLYLSGLKLCNF 163
+C +E + LSP T V+ P +G+P+ + LYL G L
Sbjct: 710 TCDGNEESSCQLSPRCPEQCTCMETV-VRCSNKGLRALP-RGMPKDVTELYLEGNHLTAV 767
Query: 164 RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI 222
R++ L+HL ++DLSNN I L F M++LS L L+ N+L V + L
Sbjct: 768 PRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGL----- 822
Query: 223 TKTLKLLDLTSNKLGHLPK 241
++L++L L N + +P+
Sbjct: 823 -RSLRVLTLHGNDISSVPE 840
Score = 41.1 bits (92), Expect = 0.007
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 13/115 (11%)
Query: 176 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLT 232
LDL N I ++ +F + NL LHL +NQ+ V RG Q K L+ L L
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAF--------QDLKQLERLRLN 117
Query: 233 SNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGR-ISTLRYFTISSNELQSL 285
NKL LP+ +++ KL L ++N I +P R I+ ++ + +N + +
Sbjct: 118 KNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCI 172
>AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 52.0 bits (119), Expect = 4e-06
Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 11/133 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S KL + +I LK L LD+S NEI+ LP + G++ +L EL++ N L V
Sbjct: 24 LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHV- 82
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI--- 266
+ D LG L LD + NK+ +P KL L + ++N + PA I
Sbjct: 83 -LPD---ELG---DLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLK 135
Query: 267 GRISTLRYFTISS 279
G++ +Y I +
Sbjct: 136 GKVHIFKYLNIQA 148
Score = 41.1 bits (92), Expect = 0.007
Identities = 22/61 (36%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 226 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L L+++ N L LPK ++ L V + +N+ ++S +P IG++ L IS NE+Q L
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVS-IPEEIGKLKDLMELDISCNEIQVL 60
Query: 286 P 286
P
Sbjct: 61 P 61
>AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 52.0 bits (119), Expect = 4e-06
Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 11/133 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S KL + +I LK L LD+S NEI+ LP + G++ +L EL++ N L V
Sbjct: 24 LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHV- 82
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI--- 266
+ D LG L LD + NK+ +P KL L + ++N + PA I
Sbjct: 83 -LPD---ELG---DLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLK 135
Query: 267 GRISTLRYFTISS 279
G++ +Y I +
Sbjct: 136 GKVHIFKYLNIQA 148
Score = 41.1 bits (92), Expect = 0.007
Identities = 22/61 (36%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 226 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L L+++ N L LPK ++ L V + +N+ ++S +P IG++ L IS NE+Q L
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVS-IPEEIGKLKDLMELDISCNEIQVL 60
Query: 286 P 286
P
Sbjct: 61 P 61
>AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 52.0 bits (119), Expect = 4e-06
Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 11/133 (8%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 209
L+ L +S KL + +I LK L LD+S NEI+ LP + G++ +L EL++ N L V
Sbjct: 24 LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHV- 82
Query: 210 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI--- 266
+ D LG L LD + NK+ +P KL L + ++N + PA I
Sbjct: 83 -LPD---ELG---DLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLK 135
Query: 267 GRISTLRYFTISS 279
G++ +Y I +
Sbjct: 136 GKVHIFKYLNIQA 148
Score = 41.1 bits (92), Expect = 0.007
Identities = 22/61 (36%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 226 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L L+++ N L LPK ++ L V + +N+ ++S +P IG++ L IS NE+Q L
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVS-IPEEIGKLKDLMELDISCNEIQVL 60
Query: 286 P 286
P
Sbjct: 61 P 61
>AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein.
Length = 850
Score = 52.0 bits (119), Expect = 4e-06
Identities = 41/139 (29%), Positives = 66/139 (47%), Gaps = 9/139 (6%)
Query: 104 SCITGDEKALHLSPLSSLSVTAKNNAPVKLVISDRSQFPAKGLPRTLQSLYLSGLKLCNF 163
+C +E + LSP T V+ P +G+P+ + LYL G L
Sbjct: 137 TCDGNEESSCQLSPRCPEQCTCMETV-VRCSNKGLRALP-RGMPKDVTELYLEGNHLTAV 194
Query: 164 RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI 222
R++ L+HL ++DLSNN I L F M++LS L L+ N+L V + L
Sbjct: 195 PRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGL----- 249
Query: 223 TKTLKLLDLTSNKLGHLPK 241
++L++L L N + +P+
Sbjct: 250 -RSLRVLTLHGNDISSVPE 267
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 52.0 bits (119), Expect = 4e-06
Identities = 41/139 (29%), Positives = 66/139 (47%), Gaps = 9/139 (6%)
Query: 104 SCITGDEKALHLSPLSSLSVTAKNNAPVKLVISDRSQFPAKGLPRTLQSLYLSGLKLCNF 163
+C +E + LSP T V+ P +G+P+ + LYL G L
Sbjct: 710 TCDGNEESSCQLSPRCPEQCTCMETV-VRCSNKGLRALP-RGMPKDVTELYLEGNHLTAV 767
Query: 164 RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI 222
R++ L+HL ++DLSNN I L F M++LS L L+ N+L V + L
Sbjct: 768 PRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGL----- 822
Query: 223 TKTLKLLDLTSNKLGHLPK 241
++L++L L N + +P+
Sbjct: 823 -RSLRVLTLHGNDISSVPE 840
Score = 41.1 bits (92), Expect = 0.007
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 13/115 (11%)
Query: 176 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLT 232
LDL N I ++ +F + NL LHL +NQ+ V RG Q K L+ L L
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAF--------QDLKQLERLRLN 117
Query: 233 SNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGR-ISTLRYFTISSNELQSL 285
NKL LP+ +++ KL L ++N I +P R I+ ++ + +N + +
Sbjct: 118 KNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCI 172
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 52.0 bits (119), Expect = 4e-06
Identities = 41/139 (29%), Positives = 66/139 (47%), Gaps = 9/139 (6%)
Query: 104 SCITGDEKALHLSPLSSLSVTAKNNAPVKLVISDRSQFPAKGLPRTLQSLYLSGLKLCNF 163
+C +E + LSP T V+ P +G+P+ + LYL G L
Sbjct: 746 TCDGNEESSCQLSPRCPEQCTCMETV-VRCSNKGLRALP-RGMPKDVTELYLEGNHLTAV 803
Query: 164 RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI 222
R++ L+HL ++DLSNN I L F M++LS L L+ N+L V + L
Sbjct: 804 PRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGL----- 858
Query: 223 TKTLKLLDLTSNKLGHLPK 241
++L++L L N + +P+
Sbjct: 859 -RSLRVLTLHGNDISSVPE 876
Score = 41.1 bits (92), Expect = 0.007
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 13/115 (11%)
Query: 176 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLT 232
LDL N I ++ +F + NL LHL +NQ+ V RG Q K L+ L L
Sbjct: 102 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAF--------QDLKQLERLRLN 153
Query: 233 SNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGR-ISTLRYFTISSNELQSL 285
NKL LP+ +++ KL L ++N I +P R I+ ++ + +N + +
Sbjct: 154 KNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCI 208
>AK058188-1|BAB71707.1| 475|Homo sapiens protein ( Homo sapiens
cDNA FLJ25459 fis, clone TST09038. ).
Length = 475
Score = 51.6 bits (118), Expect = 5e-06
Identities = 23/57 (40%), Positives = 34/57 (59%)
Query: 233 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 289
S ++ L ++W L L L NDN +SR+P I ++ L Y +SSN+L+SLP L
Sbjct: 42 SGRVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAEL 98
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/59 (44%), Positives = 34/59 (57%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
L +L+L+ L DI L +L LDLS+N++ LP E G M +L EL L NN L V
Sbjct: 58 LTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRV 116
Score = 44.0 bits (99), Expect = 0.001
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 12/110 (10%)
Query: 172 HLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITK--TLKLL 229
H A L++S + L + +L+ LHL +N L + P I K L L
Sbjct: 35 HWAELEISGR-VRSLSTSLWSLTHLTALHLNDNYLS---------RIPPDIAKLHNLVYL 84
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
DL+SNKL LP + + L L N+N++ LP +GR+ L F + +
Sbjct: 85 DLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPYELGRLFQLLNFMLDN 134
Score = 35.9 bits (79), Expect = 0.26
Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 143 AKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLA 202
A G L +SG ++ + + L HL L L++N + ++PP+ ++ NL L L+
Sbjct: 29 ANGKKSHWAELEISG-RVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLS 87
Query: 203 NNQL 206
+N+L
Sbjct: 88 SNKL 91
>BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth factor
binding protein, acid labile subunit protein.
Length = 605
Score = 51.2 bits (117), Expect = 6e-06
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 23/156 (14%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG-VR-----GVVDWR------- 215
L ++AV++LS N + LP + F + L LHL + LG +R G+ R
Sbjct: 361 LTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 216 WLLGPQITKTLKL-----LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPA-TIGR 268
L+G + L LDLTSN+L HLP +++ L KL L + N ++ LPA +G
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGP 480
Query: 269 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSN 302
+ + +S N L++LP SL+ RL Y+ + +N
Sbjct: 481 LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
>M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth factor
binding protein complex protein.
Length = 605
Score = 50.8 bits (116), Expect = 9e-06
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 23/156 (14%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG-VR-----GVVDWR------- 215
L ++AV++LS N + LP + F + L LHL + LG +R G+ R
Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 216 WLLGPQITKTLKL-----LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPA-TIGR 268
L+G + L LDLTSN+L HLP +++ L KL L + N ++ LPA +G
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGP 480
Query: 269 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSN 302
+ + +S N L++LP SL+ RL Y+ + +N
Sbjct: 481 LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
>AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like
growth factor binding protein, acid labile subunit)
protein.
Length = 605
Score = 50.8 bits (116), Expect = 9e-06
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 23/156 (14%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG-VR-----GVVDWR------- 215
L ++AV++LS N + LP + F + L LHL + LG +R G+ R
Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 216 WLLGPQITKTLKL-----LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPA-TIGR 268
L+G + L LDLTSN+L HLP +++ L KL L + N ++ LPA +G
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGP 480
Query: 269 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSN 302
+ + +S N L++LP SL+ RL Y+ + +N
Sbjct: 481 LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
>AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit
protein.
Length = 605
Score = 50.8 bits (116), Expect = 9e-06
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 23/156 (14%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG-VR-----GVVDWR------- 215
L ++AV++LS N + LP + F + L LHL + LG +R G+ R
Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 216 WLLGPQITKTLKL-----LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPA-TIGR 268
L+G + L LDLTSN+L HLP +++ L KL L + N ++ LPA +G
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGP 480
Query: 269 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSN 302
+ + +S N L++LP SL+ RL Y+ + +N
Sbjct: 481 LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 50.4 bits (115), Expect = 1e-05
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 9/117 (7%)
Query: 173 LAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 231
++ DLS N + +L P F + L EL L+ N L + + G +LK+L L
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILML 69
Query: 232 TSNKLGHLP-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 286
+N+LG +P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 70 QNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 126
Score = 45.2 bits (102), Expect = 4e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 299 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 351
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 273
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 352 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 397
Score = 38.7 bits (86), Expect = 0.037
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L + L+ N I +P F + +L LHL NN++ G + L L+
Sbjct: 133 LPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL------HNLET 186
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 263
LDL NKL P AI L +L L ++N I +P
Sbjct: 187 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 221
Score = 34.3 bits (75), Expect = 0.79
Identities = 47/158 (29%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMAN--LSELHLANNQLG 207
L++L L+ KL F I L L L NN I+ +P E M N L +H +N +
Sbjct: 184 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP-EKAFMGNPLLQTIHFYDNPIQ 242
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 266
G +++L P++ TL L + K LE L +A I LP+ +
Sbjct: 243 FVGRSAFQYL--PKL-HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAG---IRLLPSGMC 296
Query: 267 GRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
++ LR +S N+++ LP SL +C +LE I + N+
Sbjct: 297 QQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGLQHNR 333
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 50.4 bits (115), Expect = 1e-05
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 9/117 (7%)
Query: 173 LAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 231
++ DLS N + +L P F + L EL L+ N L + + G +LK+L L
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILML 69
Query: 232 TSNKLGHLP-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 286
+N+LG +P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 70 QNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 126
Score = 45.2 bits (102), Expect = 4e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 299 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 351
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 273
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 352 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 397
Score = 38.7 bits (86), Expect = 0.037
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L + L+ N I +P F + +L LHL NN++ G + L L+
Sbjct: 133 LPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL------HNLET 186
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 263
LDL NKL P AI L +L L ++N I +P
Sbjct: 187 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 221
Score = 34.3 bits (75), Expect = 0.79
Identities = 47/158 (29%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMAN--LSELHLANNQLG 207
L++L L+ KL F I L L L NN I+ +P E M N L +H +N +
Sbjct: 184 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP-EKAFMGNPLLQTIHFYDNPIQ 242
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 266
G +++L P++ TL L + K LE L +A I LP+ +
Sbjct: 243 FVGRSAFQYL--PKL-HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAG---IRLLPSGMC 296
Query: 267 GRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
++ LR +S N+++ LP SL +C +LE I + N+
Sbjct: 297 QQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGLQHNR 333
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 50.4 bits (115), Expect = 1e-05
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 9/117 (7%)
Query: 173 LAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 231
++ DLS N + +L P F + L EL L+ N L + + G +LK+L L
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILML 69
Query: 232 TSNKLGHLP-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 286
+N+LG +P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 70 QNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 126
Score = 45.2 bits (102), Expect = 4e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 299 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 351
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 273
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 352 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 397
Score = 38.7 bits (86), Expect = 0.037
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L + L+ N I +P F + +L LHL NN++ G + L L+
Sbjct: 133 LPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL------HNLET 186
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 263
LDL NKL P AI L +L L ++N I +P
Sbjct: 187 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 221
Score = 34.3 bits (75), Expect = 0.79
Identities = 47/158 (29%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMAN--LSELHLANNQLG 207
L++L L+ KL F I L L L NN I+ +P E M N L +H +N +
Sbjct: 184 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP-EKAFMGNPLLQTIHFYDNPIQ 242
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 266
G +++L P++ TL L + K LE L +A I LP+ +
Sbjct: 243 FVGRSAFQYL--PKL-HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAG---IRLLPSGMC 296
Query: 267 GRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
++ LR +S N+++ LP SL +C +LE I + N+
Sbjct: 297 QQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGLQHNR 333
>BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product
protein.
Length = 811
Score = 49.2 bits (112), Expect = 3e-05
Identities = 48/176 (27%), Positives = 82/176 (46%), Gaps = 15/176 (8%)
Query: 134 VISDRSQFPAKGLPRTLQSLYLSGLKLCNFRR-DILLLKHLAVLDLSNNEIEKLPPE-FG 191
V+ S P+ P + + L G + N D L L LDL N+I L P+ F
Sbjct: 48 VVPKTSSLPS---PHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFE 104
Query: 192 RMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLV 250
+++ L EL+L NN L L P + L++L N++ L + ++ LE LV
Sbjct: 105 KLSRLEELYLGNNLLQALA----PGTLAP--LRKLRILYANGNEISRLSRGSFEGLESLV 158
Query: 251 TLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNK 303
L+ + N + LP A + L Y + SN ++ L + +L ++++S+N+
Sbjct: 159 KLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANE 214
Score = 48.0 bits (109), Expect = 6e-05
Identities = 43/121 (35%), Positives = 63/121 (52%), Gaps = 11/121 (9%)
Query: 170 LKHLAVLDLSNNEIE---KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
L L L+LS NE++ + F + +LS L L+ N L G ++ L P+ L
Sbjct: 202 LGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHL--PR----L 255
Query: 227 KLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQS 284
LL L N+L HL P+A W LE L L+ N +S+LP A + + +L +S NEL +
Sbjct: 256 GLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSA 315
Query: 285 L 285
L
Sbjct: 316 L 316
Score = 37.5 bits (83), Expect = 0.085
Identities = 25/59 (42%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKH-LAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQL 206
L+ L L G +L +L H L LDLS NE+ L P FG + L EL L NN L
Sbjct: 279 LRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNAL 337
>BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein.
Length = 403
Score = 49.2 bits (112), Expect = 3e-05
Identities = 41/147 (27%), Positives = 62/147 (42%), Gaps = 2/147 (1%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
G P LQ L +SG L ++L L+ L L NN + P + S L +
Sbjct: 98 GFPH-LQLLDVSGNALTALGPELLALRGLRTLLAKNNRLGG-PSALPKGLAQSPLCRSLQ 155
Query: 205 QLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA 264
L + G + L+ L L N+L +P I L+ L L N I +P
Sbjct: 156 VLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPP 215
Query: 265 TIGRISTLRYFTISSNELQSLPCSLMQ 291
+G + +L Y + N++QS+P L Q
Sbjct: 216 ELGNLPSLNYLVLCDNKIQSIPPQLSQ 242
Score = 35.1 bits (77), Expect = 0.45
Identities = 19/59 (32%), Positives = 33/59 (55%)
Query: 148 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
++L+ LYL G + ++ L L L L +N+I+ +PP+ ++ +L L L NN L
Sbjct: 198 QSLECLYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLL 256
>AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein.
Length = 887
Score = 49.2 bits (112), Expect = 3e-05
Identities = 48/176 (27%), Positives = 82/176 (46%), Gaps = 15/176 (8%)
Query: 134 VISDRSQFPAKGLPRTLQSLYLSGLKLCNFRR-DILLLKHLAVLDLSNNEIEKLPPE-FG 191
V+ S P+ P + + L G + N D L L LDL N+I L P+ F
Sbjct: 124 VVPKTSSLPS---PHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFE 180
Query: 192 RMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLV 250
+++ L EL+L NN L L P + L++L N++ L + ++ LE LV
Sbjct: 181 KLSRLEELYLGNNLLQALA----PGTLAP--LRKLRILYANGNEISRLSRGSFEGLESLV 234
Query: 251 TLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNK 303
L+ + N + LP A + L Y + SN ++ L + +L ++++S+N+
Sbjct: 235 KLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANE 290
Score = 48.0 bits (109), Expect = 6e-05
Identities = 43/121 (35%), Positives = 63/121 (52%), Gaps = 11/121 (9%)
Query: 170 LKHLAVLDLSNNEIE---KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
L L L+LS NE++ + F + +LS L L+ N L G ++ L P+ L
Sbjct: 278 LGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHL--PR----L 331
Query: 227 KLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQS 284
LL L N+L HL P+A W LE L L+ N +S+LP A + + +L +S NEL +
Sbjct: 332 GLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSA 391
Query: 285 L 285
L
Sbjct: 392 L 392
Score = 37.5 bits (83), Expect = 0.085
Identities = 25/59 (42%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKH-LAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQL 206
L+ L L G +L +L H L LDLS NE+ L P FG + L EL L NN L
Sbjct: 355 LRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNAL 413
>BC026112-1|AAH26112.1| 116|Homo sapiens hypothetical protein
LOC401387 protein.
Length = 116
Score = 48.8 bits (111), Expect = 3e-05
Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 11/99 (11%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI--TKTLK 227
+ L LD+SNN I ++P G + NL LH NNQ+ L P + L+
Sbjct: 1 MTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQIS---------YLPPSLLSLNDLQ 51
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 266
L+L+ N L LP AI + L + +DN + R P I
Sbjct: 52 QLNLSGNNLTALPSAICNIFSLKEINFDDNPLLRPPVEI 90
Score = 48.8 bits (111), Expect = 3e-05
Identities = 23/64 (35%), Positives = 41/64 (64%)
Query: 226 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
LK LD+++N + +P+ I +L LV+L A +N IS LP ++ ++ L+ +S N L +L
Sbjct: 4 LKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTAL 63
Query: 286 PCSL 289
P ++
Sbjct: 64 PSAI 67
Score = 33.5 bits (73), Expect = 1.4
Identities = 19/57 (33%), Positives = 31/57 (54%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
L+ L +S + R+I L++L L NN+I LPP + +L +L+L+ N L
Sbjct: 4 LKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNL 60
Score = 32.3 bits (70), Expect = 3.2
Identities = 18/73 (24%), Positives = 34/73 (46%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
+ L L +N++ +LP ++ L L L + N ++ LP+ I I +L+ N L
Sbjct: 25 RNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAICNIFSLKEINFDDNPLL 84
Query: 284 SLPCSLMQCRLEY 296
P + + + Y
Sbjct: 85 RPPVEICKGKQLY 97
>AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein.
Length = 745
Score = 48.4 bits (110), Expect = 5e-05
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 8/140 (5%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLA 202
+GLP + +L LS K+ RR + + L L++NE+ + P G +A LS+L
Sbjct: 47 EGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEP--GALAVLSQLK-- 102
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISR 261
N L + + W ++ L+LL + N+LG LP+ A+ L L +L+ N+N +
Sbjct: 103 NLDLSHNFISSFPWSDLRNLS-ALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRT 161
Query: 262 L-PATIGRISTLRYFTISSN 280
L P T +S L + + N
Sbjct: 162 LAPGTFDALSALSHLQLYHN 181
>AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein.
Length = 785
Score = 48.4 bits (110), Expect = 5e-05
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 8/140 (5%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLA 202
+GLP + +L LS K+ RR + + L L++NE+ + P G +A LS+L
Sbjct: 87 EGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEP--GALAVLSQLK-- 142
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISR 261
N L + + W ++ L+LL + N+LG LP+ A+ L L +L+ N+N +
Sbjct: 143 NLDLSHNFISSFPWSDLRNLS-ALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRT 201
Query: 262 L-PATIGRISTLRYFTISSN 280
L P T +S L + + N
Sbjct: 202 LAPGTFDALSALSHLQLYHN 221
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 48.0 bits (109), Expect = 6e-05
Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 12/153 (7%)
Query: 136 SDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMA 194
S ++FP L+SL L+G ++ + + + L +L VLDLS N +E LP F
Sbjct: 316 SQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP-SFSVCQ 374
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLK 253
L ++ L +N++ V ++ LL +L+ L+L NK+ + P A L L+ L
Sbjct: 375 KLQKIDLRHNEIYEIKVDTFQQLL------SLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 428
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNE-LQSL 285
+ N++S P T + L + ++ N LQSL
Sbjct: 429 LSSNLLSSFPIT--GLHGLTHLKLTGNHALQSL 459
Score = 42.3 bits (95), Expect = 0.003
Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 9/114 (7%)
Query: 176 LDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
LDLS N I +L P + L EL LA N L + L +LK+L L +N
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLY------SLKVLMLQNN 124
Query: 235 KLGHLP-KAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 286
+L H+P +A+ L L +L+ + N IS + P+ + +LR+ + N L +P
Sbjct: 125 QLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIP 178
Score = 39.5 bits (88), Expect = 0.021
Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L + L+ N+I +P FG +++L LHL NN++ G + L +L+
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL------HSLET 238
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 263
LDL N L P AI L L L + N I +P
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIP 273
Score = 38.7 bits (86), Expect = 0.037
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L LDL+ N +++ P ++NL EL +N +R + + ++ P + T+
Sbjct: 233 LHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSN--NIRSIPEKAFVGNPSLI-TIHFY 289
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKAND-NMISRLPATIGRISTLRYFTISSNELQSLP-- 286
D +G A L +L TL N + I+ P G + L T++ ++ SLP
Sbjct: 290 DNPIQFVGR--SAFQHLPELRTLTLNGASQITEFPDLTG-TANLESLTLTGAQISSLPQT 346
Query: 287 -CSLMQCRLEYIDISSNKFDN 306
C+ + L+ +D+S N ++
Sbjct: 347 VCNQLP-NLQVLDLSYNLLED 366
Score = 35.1 bits (77), Expect = 0.45
Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 8/157 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG 207
+L++L L+ L F I L +L L +N I +P + F +L +H +N +
Sbjct: 235 SLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQ 294
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 266
G ++ L P++ +TL L ++++ P + L +L IS LP T+
Sbjct: 295 FVGRSAFQHL--PEL-RTLTLNG--ASQITEFPD-LTGTANLESLTLTGAQISSLPQTVC 348
Query: 267 GRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
++ L+ +S N L+ LP + +L+ ID+ N+
Sbjct: 349 NQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNE 385
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 48.0 bits (109), Expect = 6e-05
Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 12/153 (7%)
Query: 136 SDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMA 194
S ++FP L+SL L+G ++ + + + L +L VLDLS N +E LP F
Sbjct: 292 SQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP-SFSVCQ 350
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLK 253
L ++ L +N++ V ++ LL +L+ L+L NK+ + P A L L+ L
Sbjct: 351 KLQKIDLRHNEIYEIKVDTFQQLL------SLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 404
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNE-LQSL 285
+ N++S P T + L + ++ N LQSL
Sbjct: 405 LSSNLLSSFPIT--GLHGLTHLKLTGNHALQSL 435
Score = 44.4 bits (100), Expect = 7e-04
Identities = 37/135 (27%), Positives = 67/135 (49%), Gaps = 7/135 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L LDL+ N +++ P ++NL ELH +N + G ++ L P++ +TL L
Sbjct: 233 LHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHL--PEL-RTLTLN 289
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI-GRISTLRYFTISSNELQSLPCS 288
++++ P + L +L IS LP T+ ++ L+ +S N L+ LP
Sbjct: 290 G--ASQITEFPD-LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSF 346
Query: 289 LMQCRLEYIDISSNK 303
+ +L+ ID+ N+
Sbjct: 347 SVCQKLQKIDLRHNE 361
Score = 42.3 bits (95), Expect = 0.003
Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 9/114 (7%)
Query: 176 LDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
LDLS N I +L P + L EL LA N L + L +LK+L L +N
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLY------SLKVLMLQNN 124
Query: 235 KLGHLP-KAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 286
+L H+P +A+ L L +L+ + N IS + P+ + +LR+ + N L +P
Sbjct: 125 QLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIP 178
Score = 38.7 bits (86), Expect = 0.037
Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 9/134 (6%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L + L+ N+I +P FG +++L LHL NN++ G + L +L+
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL------HSLET 238
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTIS-SNELQSLP 286
LDL N L P AI L L L DN I + + + LR T++ ++++ P
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP 298
Query: 287 CSLMQCRLEYIDIS 300
LE + ++
Sbjct: 299 DLTGTANLESLTLT 312
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 48.0 bits (109), Expect = 6e-05
Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 12/153 (7%)
Query: 136 SDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMA 194
S ++FP L+SL L+G ++ + + + L +L VLDLS N +E LP F
Sbjct: 292 SQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP-SFSVCQ 350
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLK 253
L ++ L +N++ V ++ LL +L+ L+L NK+ + P A L L+ L
Sbjct: 351 KLQKIDLRHNEIYEIKVDTFQQLL------SLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 404
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNE-LQSL 285
+ N++S P T + L + ++ N LQSL
Sbjct: 405 LSSNLLSSFPIT--GLHGLTHLKLTGNHALQSL 435
Score = 44.4 bits (100), Expect = 7e-04
Identities = 37/135 (27%), Positives = 67/135 (49%), Gaps = 7/135 (5%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L LDL+ N +++ P ++NL ELH +N + G ++ L P++ +TL L
Sbjct: 233 LHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHL--PEL-RTLTLN 289
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI-GRISTLRYFTISSNELQSLPCS 288
++++ P + L +L IS LP T+ ++ L+ +S N L+ LP
Sbjct: 290 G--ASQITEFPD-LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSF 346
Query: 289 LMQCRLEYIDISSNK 303
+ +L+ ID+ N+
Sbjct: 347 SVCQKLQKIDLRHNE 361
Score = 42.3 bits (95), Expect = 0.003
Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 9/114 (7%)
Query: 176 LDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
LDLS N I +L P + L EL LA N L + L +LK+L L +N
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLY------SLKVLMLQNN 124
Query: 235 KLGHLP-KAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 286
+L H+P +A+ L L +L+ + N IS + P+ + +LR+ + N L +P
Sbjct: 125 QLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIP 178
Score = 38.7 bits (86), Expect = 0.037
Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 9/134 (6%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L + L+ N+I +P FG +++L LHL NN++ G + L +L+
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL------HSLET 238
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTIS-SNELQSLP 286
LDL N L P AI L L L DN I + + + LR T++ ++++ P
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP 298
Query: 287 CSLMQCRLEYIDIS 300
LE + ++
Sbjct: 299 DLTGTANLESLTLT 312
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 48.0 bits (109), Expect = 6e-05
Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 12/153 (7%)
Query: 136 SDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMA 194
S ++FP L+SL L+G ++ + + + L +L VLDLS N +E LP F
Sbjct: 316 SQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP-SFSVCQ 374
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLK 253
L ++ L +N++ V ++ LL +L+ L+L NK+ + P A L L+ L
Sbjct: 375 KLQKIDLRHNEIYEIKVDTFQQLL------SLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 428
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNE-LQSL 285
+ N++S P T + L + ++ N LQSL
Sbjct: 429 LSSNLLSSFPIT--GLHGLTHLKLTGNHALQSL 459
Score = 42.3 bits (95), Expect = 0.003
Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 9/114 (7%)
Query: 176 LDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
LDLS N I +L P + L EL LA N L + L +LK+L L +N
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLY------SLKVLMLQNN 124
Query: 235 KLGHLP-KAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 286
+L H+P +A+ L L +L+ + N IS + P+ + +LR+ + N L +P
Sbjct: 125 QLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIP 178
Score = 39.5 bits (88), Expect = 0.021
Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L + L+ N+I +P FG +++L LHL NN++ G + L +L+
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL------HSLET 238
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 263
LDL N L P AI L L L + N I +P
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIP 273
Score = 38.7 bits (86), Expect = 0.037
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L LDL+ N +++ P ++NL EL +N +R + + ++ P + T+
Sbjct: 233 LHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSN--NIRSIPEKAFVGNPSLI-TIHFY 289
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKAND-NMISRLPATIGRISTLRYFTISSNELQSLP-- 286
D +G A L +L TL N + I+ P G + L T++ ++ SLP
Sbjct: 290 DNPIQFVGR--SAFQHLPELRTLTLNGASQITEFPDLTG-TANLESLTLTGAQISSLPQT 346
Query: 287 -CSLMQCRLEYIDISSNKFDN 306
C+ + L+ +D+S N ++
Sbjct: 347 VCNQLP-NLQVLDLSYNLLED 366
Score = 35.1 bits (77), Expect = 0.45
Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 8/157 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG 207
+L++L L+ L F I L +L L +N I +P + F +L +H +N +
Sbjct: 235 SLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQ 294
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 266
G ++ L P++ +TL L ++++ P + L +L IS LP T+
Sbjct: 295 FVGRSAFQHL--PEL-RTLTLNG--ASQITEFPD-LTGTANLESLTLTGAQISSLPQTVC 348
Query: 267 GRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
++ L+ +S N L+ LP + +L+ ID+ N+
Sbjct: 349 NQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNE 385
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 48.0 bits (109), Expect = 6e-05
Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 12/153 (7%)
Query: 136 SDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMA 194
S ++FP L+SL L+G ++ + + + L +L VLDLS N +E LP F
Sbjct: 316 SQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP-SFSVCQ 374
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLK 253
L ++ L +N++ V ++ LL +L+ L+L NK+ + P A L L+ L
Sbjct: 375 KLQKIDLRHNEIYEIKVDTFQQLL------SLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 428
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNE-LQSL 285
+ N++S P T + L + ++ N LQSL
Sbjct: 429 LSSNLLSSFPIT--GLHGLTHLKLTGNHALQSL 459
Score = 42.3 bits (95), Expect = 0.003
Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 9/114 (7%)
Query: 176 LDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
LDLS N I +L P + L EL LA N L + L +LK+L L +N
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLY------SLKVLMLQNN 124
Query: 235 KLGHLP-KAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 286
+L H+P +A+ L L +L+ + N IS + P+ + +LR+ + N L +P
Sbjct: 125 QLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIP 178
Score = 39.5 bits (88), Expect = 0.021
Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L + L+ N+I +P FG +++L LHL NN++ G + L +L+
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL------HSLET 238
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 263
LDL N L P AI L L L + N I +P
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIP 273
Score = 38.7 bits (86), Expect = 0.037
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L LDL+ N +++ P ++NL EL +N +R + + ++ P + T+
Sbjct: 233 LHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSN--NIRSIPEKAFVGNPSLI-TIHFY 289
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKAND-NMISRLPATIGRISTLRYFTISSNELQSLP-- 286
D +G A L +L TL N + I+ P G + L T++ ++ SLP
Sbjct: 290 DNPIQFVGR--SAFQHLPELRTLTLNGASQITEFPDLTG-TANLESLTLTGAQISSLPQT 346
Query: 287 -CSLMQCRLEYIDISSNKFDN 306
C+ + L+ +D+S N ++
Sbjct: 347 VCNQLP-NLQVLDLSYNLLED 366
Score = 35.1 bits (77), Expect = 0.45
Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 8/157 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG 207
+L++L L+ L F I L +L L +N I +P + F +L +H +N +
Sbjct: 235 SLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQ 294
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 266
G ++ L P++ +TL L ++++ P + L +L IS LP T+
Sbjct: 295 FVGRSAFQHL--PEL-RTLTLNG--ASQITEFPD-LTGTANLESLTLTGAQISSLPQTVC 348
Query: 267 GRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
++ L+ +S N L+ LP + +L+ ID+ N+
Sbjct: 349 NQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNE 385
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 48.0 bits (109), Expect = 6e-05
Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 12/153 (7%)
Query: 136 SDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMA 194
S ++FP L+SL L+G ++ + + + L +L VLDLS N +E LP F
Sbjct: 316 SQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP-SFSVCQ 374
Query: 195 NLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLK 253
L ++ L +N++ V ++ LL +L+ L+L NK+ + P A L L+ L
Sbjct: 375 KLQKIDLRHNEIYEIKVDTFQQLL------SLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 428
Query: 254 ANDNMISRLPATIGRISTLRYFTISSNE-LQSL 285
+ N++S P T + L + ++ N LQSL
Sbjct: 429 LSSNLLSSFPIT--GLHGLTHLKLTGNHALQSL 459
Score = 41.9 bits (94), Expect = 0.004
Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 9/114 (7%)
Query: 176 LDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
LDLS N I +L P + L EL LA N L + L +LK+L L +N
Sbjct: 71 LDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLY------SLKVLMLQNN 124
Query: 235 KLGHLP-KAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 286
+L H+P +A+ L L +L+ + N IS + P+ + +LR+ + N L +P
Sbjct: 125 QLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIP 178
Score = 38.7 bits (86), Expect = 0.037
Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L LDL+ N +++ P ++NL EL +N +R + + ++ P + T+
Sbjct: 233 LHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSN--NIRSIPEKAFVGNPSLI-TIHFY 289
Query: 230 DLTSNKLGHLPKAIWKLEKLVTLKAND-NMISRLPATIGRISTLRYFTISSNELQSLP-- 286
D +G A L +L TL N + I+ P G + L T++ ++ SLP
Sbjct: 290 DNPIQFVGR--SAFQHLPELRTLTLNGASQITEFPDLTG-TANLESLTLTGAQISSLPQT 346
Query: 287 -CSLMQCRLEYIDISSNKFDN 306
C+ + L+ +D+S N ++
Sbjct: 347 VCNQLP-NLQVLDLSYNLLED 366
Score = 35.1 bits (77), Expect = 0.45
Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 8/157 (5%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG 207
+L++L L+ L F I L +L L +N I +P + F +L +H +N +
Sbjct: 235 SLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQ 294
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 266
G ++ L P++ +TL L ++++ P + L +L IS LP T+
Sbjct: 295 FVGRSAFQHL--PEL-RTLTLNG--ASQITEFPD-LTGTANLESLTLTGAQISSLPQTVC 348
Query: 267 GRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 303
++ L+ +S N L+ LP + +L+ ID+ N+
Sbjct: 349 NQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNE 385
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2
(Drosophila) protein.
Length = 1529
Score = 47.6 bits (108), Expect = 8e-05
Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLA 202
KG+PR + LYL G + +++ KHL ++DLSNN I L + F M L L L+
Sbjct: 750 KGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILS 809
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 241
N+L + R G K+L+LL L N + +P+
Sbjct: 810 YNRL---RCIPPRTFDG---LKSLRLLSLHGNDISVVPE 842
Score = 35.9 bits (79), Expect = 0.26
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRR-DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLA 202
+ +PR + L L+G + + D L+HL VL L N+I + E G +L EL
Sbjct: 51 RNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTI--ERGAFQDLKELERL 108
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP-KAIWKLEKLVTLKANDNMISR 261
+ LG T L LDL+ N++ +P KA + L+ + N IS
Sbjct: 109 RLNRNHLQLFPELLFLG---TAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISC 165
Query: 262 L-PATIGRISTLRYFTISSNELQSL 285
+ + L T+++N + L
Sbjct: 166 IEDGAFRALRDLEVLTLNNNNITRL 190
Score = 31.1 bits (67), Expect = 7.4
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 13/129 (10%)
Query: 171 KHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
K L +DLSNN+I +L P+ F + +L+ L L N++ + L +L+LL
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLF------SLQLL 377
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L +NK+ L A L L L DN + + G S LR I + L P
Sbjct: 378 LLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK--GTFSPLR--AIQTMHLAQNP-F 432
Query: 289 LMQCRLEYI 297
+ C L+++
Sbjct: 433 ICDCHLKWL 441
>BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 47.6 bits (108), Expect = 8e-05
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 10/118 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L +LDLS N+I LP F +ANLS L L N+L +R L + L+
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL------RRLER 128
Query: 229 LDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L L N++ H+ P A L++L+ LK DN + LP R+ L +S N L +L
Sbjct: 129 LYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSLLAL 184
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 10/142 (7%)
Query: 168 LLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLK 227
L L L +LDLS+N + L P AN+ L LA LG++ + + + + L
Sbjct: 166 LRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAG--LGLQQLDEGLF----SRLRNLH 219
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLK-ANDNMISRL-PATIGRISTLRYFTISSNELQSL 285
LD++ N+L +P I L L L+ A + I++L P + ++ L+ +S+ LQ+L
Sbjct: 220 DLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQAL 279
Query: 286 PCSL--MQCRLEYIDISSNKFD 305
P L + RL + + N F+
Sbjct: 280 PGDLSGLFPRLRLLAAARNPFN 301
Score = 35.5 bits (78), Expect = 0.34
Identities = 19/56 (33%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 150 LQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
+++L L+GL L + L++L LD+S+N++E++PP + L+ L LA N
Sbjct: 194 VEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGN 249
>BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 47.6 bits (108), Expect = 8e-05
Identities = 46/144 (31%), Positives = 73/144 (50%), Gaps = 10/144 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG 207
L+SL+L G +L R + L HL L+L+ N + +LP E F + +L L L+NN L
Sbjct: 147 LESLHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALS 206
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLPATI 266
G+ + + G +L+ L L SN + LP ++ +L L L N I+ LP +I
Sbjct: 207 --GLP--QGVFGK--LGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSI 260
Query: 267 -GRISTLRYFTISSNELQSLPCSL 289
+ L + ++ N L+ LP L
Sbjct: 261 FASLGNLTFLSLQWNMLRVLPAGL 284
Score = 42.3 bits (95), Expect = 0.003
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 9/120 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L +L L L N + LP F L L L +NQL + L L+
Sbjct: 264 LGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHL------SNLRS 317
Query: 229 LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 286
L L+ N + HLP I++ LE+LV L N ++ L PA +S L ++S N+L +LP
Sbjct: 318 LMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLP 377
>BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein.
Length = 601
Score = 47.6 bits (108), Expect = 8e-05
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 10/118 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L +LDLS N+I LP F +ANLS L L N+L +R L + L+
Sbjct: 3 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL------RRLER 56
Query: 229 LDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L L N++ H+ P A L++L+ LK DN + LP R+ L +S N L +L
Sbjct: 57 LYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSLLAL 112
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 10/142 (7%)
Query: 168 LLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLK 227
L L L +LDLS+N + L P AN+ L LA LG++ + + + + L
Sbjct: 94 LRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAG--LGLQQLDEGLF----SRLRNLH 147
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLK-ANDNMISRL-PATIGRISTLRYFTISSNELQSL 285
LD++ N+L +P I L L L+ A + I++L P + ++ L+ +S+ LQ+L
Sbjct: 148 DLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQAL 207
Query: 286 PCSL--MQCRLEYIDISSNKFD 305
P L + RL + + N F+
Sbjct: 208 PGDLSGLFPRLRLLAAARNPFN 229
Score = 35.5 bits (78), Expect = 0.34
Identities = 19/56 (33%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 150 LQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
+++L L+GL L + L++L LD+S+N++E++PP + L+ L LA N
Sbjct: 122 VEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGN 177
>AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein.
Length = 673
Score = 47.6 bits (108), Expect = 8e-05
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 10/118 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L +LDLS N+I LP F +ANLS L L N+L +R L + L+
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL------RRLER 128
Query: 229 LDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L L N++ H+ P A L++L+ LK DN + LP R+ L +S N L +L
Sbjct: 129 LYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSLLAL 184
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 10/142 (7%)
Query: 168 LLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLK 227
L L L +LDLS+N + L P AN+ L LA LG++ + + + + L
Sbjct: 166 LRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAG--LGLQQLDEGLF----SRLRNLH 219
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLK-ANDNMISRL-PATIGRISTLRYFTISSNELQSL 285
LD++ N+L +P I L L L+ A + I++L P + ++ L+ +S+ LQ+L
Sbjct: 220 DLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQAL 279
Query: 286 PCSL--MQCRLEYIDISSNKFD 305
P L + RL + + N F+
Sbjct: 280 PGDLSGLFPRLRLLAAARNPFN 301
Score = 35.5 bits (78), Expect = 0.34
Identities = 19/56 (33%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 150 LQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
+++L L+GL L + L++L LD+S+N++E++PP + L+ L LA N
Sbjct: 194 VEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGN 249
>AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 47.6 bits (108), Expect = 8e-05
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 10/118 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L +LDLS N+I LP F +ANLS L L N+L +R L + L+
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL------RRLER 128
Query: 229 LDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
L L N++ H+ P A L++L+ LK DN + LP R+ L +S N L +L
Sbjct: 129 LYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSLLAL 184
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 10/142 (7%)
Query: 168 LLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLK 227
L L L +LDLS+N + L P AN+ L LA LG++ + + + + L
Sbjct: 166 LRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAG--LGLQQLDEGLF----SRLRNLH 219
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLK-ANDNMISRL-PATIGRISTLRYFTISSNELQSL 285
LD++ N+L +P I L L L+ A + I++L P + ++ L+ +S+ LQ+L
Sbjct: 220 DLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQAL 279
Query: 286 PCSL--MQCRLEYIDISSNKFD 305
P L + RL + + N F+
Sbjct: 280 PGDLSGLFPRLRLLAAARNPFN 301
Score = 35.5 bits (78), Expect = 0.34
Identities = 19/56 (33%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 150 LQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
+++L L+GL L + L++L LD+S+N++E++PP + L+ L LA N
Sbjct: 194 VEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGN 249
>AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 232
Score = 47.6 bits (108), Expect = 8e-05
Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 180 NNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL 239
NN E P F + L EL L+ N L + + G +LK+L L +N+LG +
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILMLQNNQLGGI 55
Query: 240 P-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 286
P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 56 PAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 104
Score = 37.1 bits (82), Expect = 0.11
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 11/140 (7%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L L L +N + ++P + L + LA N++ + D+ + Q +L +
Sbjct: 87 LSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRIS--HIPDYAF----QNLTSLVV 140
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNM-ISRLPATIGRISTLRYFTISSNELQSLPC 287
LDL NKL P AI L +L L N M I P G S L T++ ++ LP
Sbjct: 141 LDLNYNKLQEFPVAIRTLGRLQELSLNGAMDIQEFPDLKGTTS-LEILTLTRAGIRLLPS 199
Query: 288 SLMQ--CRLEYIDISSNKFD 305
+ Q RL +++S N+ +
Sbjct: 200 GMCQQLPRLRVLELSHNQIE 219
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 47.6 bits (108), Expect = 8e-05
Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLA 202
KG+PR + LYL G + +++ KHL ++DLSNN I L + F M L L L+
Sbjct: 746 KGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILS 805
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 241
N+L + R G K+L+LL L N + +P+
Sbjct: 806 YNRL---RCIPPRTFDG---LKSLRLLSLHGNDISVVPE 838
Score = 35.9 bits (79), Expect = 0.26
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRR-DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLA 202
+ +PR + L L+G + + D L+HL VL L N+I + E G +L EL
Sbjct: 51 RNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTI--ERGAFQDLKELERL 108
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP-KAIWKLEKLVTLKANDNMISR 261
+ LG T L LDL+ N++ +P KA + L+ + N IS
Sbjct: 109 RLNRNHLQLFPELLFLG---TAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISC 165
Query: 262 L-PATIGRISTLRYFTISSNELQSL 285
+ + L T+++N + L
Sbjct: 166 IEDGAFRALRDLEVLTLNNNNITRL 190
Score = 31.1 bits (67), Expect = 7.4
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 13/129 (10%)
Query: 171 KHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
K L +DLSNN+I +L P+ F + +L+ L L N++ + L +L+LL
Sbjct: 328 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLF------SLQLL 381
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L +NK+ L A L L L DN + + G S LR I + L P
Sbjct: 382 LLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK--GTFSPLR--AIQTMHLAQNP-F 436
Query: 289 LMQCRLEYI 297
+ C L+++
Sbjct: 437 ICDCHLKWL 445
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 47.6 bits (108), Expect = 8e-05
Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLA 202
KG+PR + LYL G + +++ KHL ++DLSNN I L + F M L L L+
Sbjct: 742 KGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILS 801
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 241
N+L + R G K+L+LL L N + +P+
Sbjct: 802 YNRL---RCIPPRTFDG---LKSLRLLSLHGNDISVVPE 834
Score = 35.9 bits (79), Expect = 0.26
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRR-DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLA 202
+ +PR + L L+G + + D L+HL VL L N+I + E G +L EL
Sbjct: 51 RNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTI--ERGAFQDLKELERL 108
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP-KAIWKLEKLVTLKANDNMISR 261
+ LG T L LDL+ N++ +P KA + L+ + N IS
Sbjct: 109 RLNRNHLQLFPELLFLG---TAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISC 165
Query: 262 L-PATIGRISTLRYFTISSNELQSL 285
+ + L T+++N + L
Sbjct: 166 IEDGAFRALRDLEVLTLNNNNITRL 190
Score = 31.1 bits (67), Expect = 7.4
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 13/129 (10%)
Query: 171 KHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
K L +DLSNN+I +L P+ F + +L+ L L N++ + L +L+LL
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLF------SLQLL 377
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L +NK+ L A L L L DN + + G S LR I + L P
Sbjct: 378 LLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK--GTFSPLR--AIQTMHLAQNP-F 432
Query: 289 LMQCRLEYI 297
+ C L+++
Sbjct: 433 ICDCHLKWL 441
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 47.6 bits (108), Expect = 8e-05
Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLA 202
KG+PR + LYL G + +++ KHL ++DLSNN I L + F M L L L+
Sbjct: 750 KGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILS 809
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 241
N+L + R G K+L+LL L N + +P+
Sbjct: 810 YNRL---RCIPPRTFDG---LKSLRLLSLHGNDISVVPE 842
Score = 35.9 bits (79), Expect = 0.26
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRR-DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLA 202
+ +PR + L L+G + + D L+HL VL L N+I + E G +L EL
Sbjct: 51 RNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTI--ERGAFQDLKELERL 108
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP-KAIWKLEKLVTLKANDNMISR 261
+ LG T L LDL+ N++ +P KA + L+ + N IS
Sbjct: 109 RLNRNHLQLFPELLFLG---TAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISC 165
Query: 262 L-PATIGRISTLRYFTISSNELQSL 285
+ + L T+++N + L
Sbjct: 166 IEDGAFRALRDLEVLTLNNNNITRL 190
Score = 31.1 bits (67), Expect = 7.4
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 13/129 (10%)
Query: 171 KHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
K L +DLSNN+I +L P+ F + +L+ L L N++ + L +L+LL
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLF------SLQLL 377
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L +NK+ L A L L L DN + + G S LR I + L P
Sbjct: 378 LLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK--GTFSPLR--AIQTMHLAQNP-F 432
Query: 289 LMQCRLEYI 297
+ C L+++
Sbjct: 433 ICDCHLKWL 441
>DQ013130-1|AAY67799.1| 2014|Homo sapiens leucine-rich repeat kinase
1 protein.
Length = 2014
Score = 47.2 bits (107), Expect = 1e-04
Identities = 45/137 (32%), Positives = 70/137 (51%), Gaps = 15/137 (10%)
Query: 176 LDLSNNEIEKLPPEFG-RMANLSELHLANNQLG-VRGVVDWRWLLGPQITKTLKLLDLTS 233
LDLS N + LP + NL +L+L++N LG + GV ++ ++ + +D++S
Sbjct: 282 LDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEIICSRLLE----IDISS 337
Query: 234 NKLGHLPKAIWKLEKLVTLKANDNMISRL----PAT--IGRISTLRYFTISSNELQSLPC 287
NKL HLP L KL L A+ N + +L AT IG + L+ IS N+L LP
Sbjct: 338 NKLSHLPPGFLHLSKLQKLTASKNCLEKLFEEENATNWIG-LRKLQELDISDNKLTELPA 396
Query: 288 SLMQC--RLEYIDISSN 302
+ L +++S N
Sbjct: 397 LFLHSFKSLNSLNVSRN 413
Score = 37.5 bits (83), Expect = 0.085
Identities = 37/146 (25%), Positives = 68/146 (46%), Gaps = 16/146 (10%)
Query: 170 LKHLAVLDLSNNEIEKLPPEF-GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L+ L LD+S+N++ +LP F +L+ L+++ N L V W LK
Sbjct: 378 LRKLQELDISDNKLTELPALFLHSFKSLNSLNVSRNNLKV---FPDPWAC------PLKC 428
Query: 229 LDLTSNKLGHLPKAI---WKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
+ N L LP + WK L + ++N + +P + ++ L + + N+L +L
Sbjct: 429 CKASRNALECLPDKMAVFWK-NHLKDVDFSENALKEVPLGLFQLDALMFLRLQGNQLAAL 487
Query: 286 -PCSLMQCR-LEYIDISSNKFDNKQN 309
P CR L+ +D+S N+ ++
Sbjct: 488 PPQEKWTCRQLKTLDLSRNQLGKNED 513
Score = 37.1 bits (82), Expect = 0.11
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 16/145 (11%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL----GVRGVVDWRWLLGPQ 221
D ++ L +D+S+N++ LPP F ++ L +L + N L +W L
Sbjct: 323 DEIICSRLLEIDISSNKLSHLPPGFLHLSKLQKLTASKNCLEKLFEEENATNWIGL---- 378
Query: 222 ITKTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 280
+ L+ LD++ NKL LP + + L +L + N + P L+ S N
Sbjct: 379 --RKLQELDISDNKLTELPALFLHSFKSLNSLNVSRNNLKVFPDPWA--CPLKCCKASRN 434
Query: 281 ELQSLPCSL---MQCRLEYIDISSN 302
L+ LP + + L+ +D S N
Sbjct: 435 ALECLPDKMAVFWKNHLKDVDFSEN 459
Score = 36.7 bits (81), Expect = 0.15
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
Query: 140 QFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNE-IEKLPPEFGRMANLSE 198
+FPA L +L+ L L+ L + LLK L+ L L NN + +LPPE G++ NL +
Sbjct: 540 EFPAF-LSESLEVLCLNDNHLDTVPPSVCLLKSLSELYLGNNPGLRELPPELGQLGNLWQ 598
Query: 199 L 199
L
Sbjct: 599 L 599
Score = 32.7 bits (71), Expect = 2.4
Identities = 15/36 (41%), Positives = 24/36 (66%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
L + L VL L++N ++ +PP + +LSEL+L NN
Sbjct: 545 LSESLEVLCLNDNHLDTVPPSVCLLKSLSELYLGNN 580
>DQ355157-1|ABC79623.1| 334|Homo sapiens cytokeratin associated
protein protein.
Length = 334
Score = 46.8 bits (106), Expect = 1e-04
Identities = 46/130 (35%), Positives = 62/130 (47%), Gaps = 12/130 (9%)
Query: 173 LAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLKLLD 230
L L L +N + LPP F L L L N G+ V V W LG L+LLD
Sbjct: 73 LRALLLDHNRVRALPPGAFAGAGALQRLDLREN--GLHSVHVRAFWGLG-----ALQLLD 125
Query: 231 LTSNKLGHL-PKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCS 288
L++N+L L P L L L N ++RL PA +G + LR ++ NEL +L
Sbjct: 126 LSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPG 185
Query: 289 LMQCRLEYID 298
L+ RL +D
Sbjct: 186 LLG-RLPALD 194
>BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein.
Length = 465
Score = 46.8 bits (106), Expect = 1e-04
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 14/150 (9%)
Query: 166 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW--RWLLGPQ-- 221
++ L+H+ LDL +N++ L N+ LH NQL + + + L
Sbjct: 50 EVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDICGYFLKALYASSNE 107
Query: 222 --------ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 273
+ L +D++ N+L ++P+ + + KL L N I LPA + S+LR
Sbjct: 108 LVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLR 167
Query: 274 YFTISSNELQSLPCSLMQCRLEYIDISSNK 303
N+L LP L + +E +D+ N+
Sbjct: 168 KLLAGHNQLARLPERLERTSVEVLDVQHNQ 197
Score = 44.0 bits (99), Expect = 0.001
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 16/144 (11%)
Query: 168 LLLK--HLAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQI 222
LL+K L L+ S N++E LPP N L EL+L NN L + V P +
Sbjct: 205 LLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCV--------PLL 256
Query: 223 T--KTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 279
T LK+L + N+L P + + KLE+L + + N + +P TI + S
Sbjct: 257 TGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHS 316
Query: 280 NELQSLPCSLMQCRLEYIDISSNK 303
N ++ P + ++ +D+S N+
Sbjct: 317 NCIEVFPEVMQLPEIKCVDLSCNE 340
Score = 41.1 bits (92), Expect = 0.007
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
Query: 223 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
++ L++LD+ N++ LP ++ L L A N ++RLP + R S + + N+L
Sbjct: 140 SRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQL 198
Query: 283 QSLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 315
LP +L+ L +++ S+NK ++ + S++
Sbjct: 199 LELPPNLLMKADSLRFLNASANKLESLPPATLSEE 233
Score = 36.7 bits (81), Expect = 0.15
Identities = 49/180 (27%), Positives = 80/180 (44%), Gaps = 22/180 (12%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 205
+P L + +S +L N + + L VLD+ +N+I +LP ++L +L +NQ
Sbjct: 116 VPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQ 175
Query: 206 LG------------VRGVVDWRWL-LGPQI---TKTLKLLDLTSNKLGHLPKAIWKLEKL 249
L V V + L L P + +L+ L+ ++NKL LP A E
Sbjct: 176 LARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETN 235
Query: 250 VTLK----ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNK 303
L+ N+++ + + L+ ++ N LQS P S M LE ID+S NK
Sbjct: 236 SILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNK 295
Score = 31.1 bits (67), Expect = 7.4
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 5/78 (6%)
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
LDL NKLG L I+ + L N + L G L+ SSNEL L
Sbjct: 60 LDLRDNKLGDLDAMIFN--NIEVLHCERNQLVTLDIC-GYF--LKALYASSNELVQLDVY 114
Query: 289 LMQCRLEYIDISSNKFDN 306
+ L Y+D+S N+ +N
Sbjct: 115 PVPNYLSYMDVSRNRLEN 132
>BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein.
Length = 512
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/141 (29%), Positives = 71/141 (50%), Gaps = 12/141 (8%)
Query: 169 LLKHLAVLDLSNNEI-EKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLK 227
L + L V DL+ N++ E P FG L ++L NNQL G+ + + ++ +
Sbjct: 143 LPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAF----RGSEAIA 198
Query: 228 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNEL--QS 284
L L++N+L +LP ++ L L +N+IS++P + R + LR + N+L
Sbjct: 199 TLSLSNNQLSYLPPSL--PPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSG 256
Query: 285 LPCSLMQ--CRLEYIDISSNK 303
L + LEY+D+S N+
Sbjct: 257 LDATTFSKLHSLEYLDLSHNQ 277
Score = 37.9 bits (84), Expect = 0.064
Identities = 35/119 (29%), Positives = 60/119 (50%), Gaps = 16/119 (13%)
Query: 178 LSNNEIEK--LPPEFGRMAN-LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
L NN++ LPP+ R + ++ L L+NNQL L P + +L+ L L +N
Sbjct: 176 LHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSY---------LPPSLPPSLERLHLQNN 226
Query: 235 KLGHLPK-AIWKLEKLVTLKANDNMI--SRLPAT-IGRISTLRYFTISSNELQSLPCSL 289
+ +P+ A+ + +L L N + S L AT ++ +L Y +S N+L ++P L
Sbjct: 227 LISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL 285
Score = 31.5 bits (68), Expect = 5.6
Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 17/162 (10%)
Query: 131 VKLVISDRSQFPAKGLP-------RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEI 183
++ ++ +Q + GLP R L +L+L G L R L + L L L +N +
Sbjct: 313 LRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLD--RVPPALPRRLRALVLPHNHV 370
Query: 184 EKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKA 242
L + L+EL+LA N+L V + + + L+ LDL N+L LP
Sbjct: 371 AALGARDLVATPGLTELNLAYNRLASARVHHRAF----RRLRALRSLDLAGNQLTRLPMG 426
Query: 243 IWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQ 283
+ L TL+ N + L P + + LR +++ N L+
Sbjct: 427 L--PTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLR 466
>AL929554-11|CAH72880.1| 334|Homo sapiens leucine rich repeat
containing 26 protein.
Length = 334
Score = 46.8 bits (106), Expect = 1e-04
Identities = 46/130 (35%), Positives = 62/130 (47%), Gaps = 12/130 (9%)
Query: 173 LAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLKLLD 230
L L L +N + LPP F L L L N G+ V V W LG L+LLD
Sbjct: 73 LRALLLDHNRVRALPPGAFAGAGALQRLDLREN--GLHSVHVRAFWGLG-----ALQLLD 125
Query: 231 LTSNKLGHL-PKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCS 288
L++N+L L P L L L N ++RL PA +G + LR ++ NEL +L
Sbjct: 126 LSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPG 185
Query: 289 LMQCRLEYID 298
L+ RL +D
Sbjct: 186 LLG-RLPALD 194
>BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine rich
repeat protein phosphatase-like protein.
Length = 1323
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN--QLGVRGVVDWRWLLGPQITKTLKL 228
+ ++ +DLS +E++P +++ L+L +N QL G +D + LK
Sbjct: 249 QRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQ-----LKG 303
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L+L+ NKLG P + ++ L L + N LP+ IG + L+ + N L +LP
Sbjct: 304 LNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEE 363
Query: 289 LMQC-RLEYIDISSNKF 304
L +L + IS N F
Sbjct: 364 LGNLQQLSSLGISFNNF 380
Score = 44.8 bits (101), Expect = 6e-04
Identities = 49/164 (29%), Positives = 77/164 (46%), Gaps = 14/164 (8%)
Query: 148 RTLQSLYLSGLKLCNFRRDIL--LLKH--LAVLDLSNNEIEKLPPE-FGRMANLSELHLA 202
R L SL L L L + L L++H L VLDL +N + +LP F + NL L+ +
Sbjct: 543 RILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNAS 602
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMIS 260
N L G + L+LL LT+N L +P + L + AN N +
Sbjct: 603 ANSLESLPSA----CTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILHLAN-NQLQ 657
Query: 261 RLPAT-IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
PA+ + ++ L +S N+L+++P ++ C RL + SN
Sbjct: 658 TFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSN 701
Score = 44.4 bits (100), Expect = 7e-04
Identities = 39/135 (28%), Positives = 64/135 (47%), Gaps = 10/135 (7%)
Query: 172 HLAVLDLSNNEIEKLPPEFGRMANLSEL---HLANNQLGVRGVVDWRWLLGPQITKTLKL 228
+L L+ S N +E LP +LS L +L NN L + + L+G L++
Sbjct: 595 NLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPV---LVGHL---HLRI 648
Query: 229 LDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
L L +N+L P + + KLE+L L + N + +P TI L SN + P
Sbjct: 649 LHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPE 708
Query: 288 SLMQCRLEYIDISSN 302
L +++++D+S N
Sbjct: 709 ILQLPQIQFVDLSCN 723
Score = 35.1 bits (77), Expect = 0.45
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K +++LD++ N L +P I L L N + LP + I L + N L
Sbjct: 525 KKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNLPTLVEHI-PLEVLDLQHNALT 583
Query: 284 SLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 315
LP +L L Y++ S+N ++ + T ++
Sbjct: 584 RLPDTLFSKALNLRYLNASANSLESLPSACTGEE 617
>AK127729-1|BAC87105.1| 870|Homo sapiens protein ( Homo sapiens
cDNA FLJ45829 fis, clone NT2RP8006452. ).
Length = 870
Score = 46.4 bits (105), Expect = 2e-04
Identities = 40/139 (28%), Positives = 69/139 (49%), Gaps = 10/139 (7%)
Query: 150 LQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 208
L+ L L L +F + + LK L LDL +N+ P +M+ ++ L ++ N +G
Sbjct: 612 LEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGP 671
Query: 209 RGVVDWRWLLGPQI-TKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATI 266
V+D P + TLK +L+ N+L +P+ + +EKL L N IS + + +
Sbjct: 672 SVVLD------PTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL 725
Query: 267 GRISTLRYFTISSNELQSL 285
R+ L+ +S N + SL
Sbjct: 726 -RLKELKILNLSKNHISSL 743
Score = 44.4 bits (100), Expect = 7e-04
Identities = 38/103 (36%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 111 KALHLSP--LSSLSVTAKNNAPVKLVISDRSQFPAKG--LPRTLQSLYLSGLKLCNFRRD 166
K L+LS +SSLS P S R F A LP ++ L LS K
Sbjct: 731 KILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIPEA 790
Query: 167 ILLLKHLAVLDLSNNEIEKLP-PEFGRMANLSELHLANNQLGV 208
IL L HL LD+S+N+I+ LP P + NL EL ++NQ+ +
Sbjct: 791 ILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISI 833
Score = 40.7 bits (91), Expect = 0.009
Identities = 46/159 (28%), Positives = 66/159 (41%), Gaps = 16/159 (10%)
Query: 150 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLAN-NQLGV 208
L+ L L G K+ L LK L +L+LS N I L F E A N L
Sbjct: 708 LEQLILEGNKISGICSP-LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAA 766
Query: 209 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI-G 267
P + ++ +L L+ NK +P+AI L L +L + N I LP
Sbjct: 767 M----------PFLPPSMTILKLSQNKFSCIPEAILNLPHLRSLDMSSNDIQYLPGPAHW 816
Query: 268 RISTLRYFTISSNELQSLPCS---LMQCRLEYIDISSNK 303
+ LR S N++ L S + R+E + +S NK
Sbjct: 817 KSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNK 855
Score = 30.7 bits (66), Expect = 9.8
Identities = 52/212 (24%), Positives = 96/212 (45%), Gaps = 29/212 (13%)
Query: 115 LSPLSSLSVTAKNNAPVKLVISDRSQFPAKGLPRTLQSLY---LSGLKLCNFRRDILLLK 171
LS +SV ++ ++L + + FP + L TL+SL L K +F +L +
Sbjct: 599 LSQKCCISVHLEHLEKLELHQNALTSFPQQ-LCETLKSLTHLDLHSNKFTSFPSYLLKMS 657
Query: 172 HLAVLDLSNNEIEK---LPPEFGRMANLSELHLANNQL-----GVRGVVD---------- 213
+A LD+S N+I L P + L + +L+ NQL + VV+
Sbjct: 658 CIANLDVSRNDIGPSVVLDPTV-KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 716
Query: 214 -WRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGRIST 271
+ P K LK+L+L+ N + L + + K+ + A N ++ +P ++
Sbjct: 717 KISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTI 776
Query: 272 LRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
L+ +S N+ +P +++ L +D+SSN
Sbjct: 777 LK---LSQNKFSCIPEAILNLPHLRSLDMSSN 805
>AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ42687 fis, clone BRAMY3001794, moderately
similar to Rattus norvegicus SCN circadian oscillatory
protein (Scop). ).
Length = 423
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN--QLGVRGVVDWRWLLGPQITKTLKL 228
+ ++ +DLS +E++P +++ L+L +N QL G +D + LK
Sbjct: 249 QRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQ-----LKG 303
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L+L+ NKLG P + ++ L L + N LP+ IG + L+ + N L +LP
Sbjct: 304 LNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEE 363
Query: 289 LMQC-RLEYIDISSNKF 304
L +L + IS N F
Sbjct: 364 LGNLQQLSSLGISFNNF 380
>AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein.
Length = 1258
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN--QLGVRGVVDWRWLLGPQITKTLKL 228
+ ++ +DLS +E++P +++ L+L +N QL G +D + LK
Sbjct: 251 QRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQ-----LKG 305
Query: 229 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 288
L+L+ NKLG P + ++ L L + N LP+ IG + L+ + N L +LP
Sbjct: 306 LNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEE 365
Query: 289 LMQC-RLEYIDISSNKF 304
L +L + IS N F
Sbjct: 366 LGNLQQLSSLGISFNNF 382
Score = 45.2 bits (102), Expect = 4e-04
Identities = 41/140 (29%), Positives = 63/140 (45%), Gaps = 16/140 (11%)
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 230
K + VLD+S N + ++P LS L L LG V + L+ I L++LD
Sbjct: 527 KKIEVLDVSYNLLTEVPVRI-----LSSLSLRKLMLGHNHVQNLPTLV-EHIP--LEVLD 578
Query: 231 LTSNKLGHLPKAIW--------KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 282
L N L LP ++ KLE+L L + N + +P TI L SN +
Sbjct: 579 LQHNALTRLPDTLFSKALNKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNI 638
Query: 283 QSLPCSLMQCRLEYIDISSN 302
P L +++++D+S N
Sbjct: 639 SIFPEILQLPQIQFVDLSCN 658
>BC050097-1|AAH50097.1| 383|Homo sapiens LRRC27 protein protein.
Length = 383
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 7/117 (5%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
+LDLS + + +L F R+ +L +LHL N L V D+ LL P +T LDL N
Sbjct: 49 ILDLSESGLCRLEEVF-RIPSLQQLHLQRNALCVIPQ-DFFQLL-PNLT----WLDLRYN 101
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++ LP I + L TL N I LP +G ++TL+ + L+ P ++Q
Sbjct: 102 RIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPLEFPPQLVVQ 158
>AL590105-6|CAI13017.1| 530|Homo sapiens novel protein protein.
Length = 530
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 7/117 (5%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
+LDLS + + +L F R+ +L +LHL N L V D+ LL P +T LDL N
Sbjct: 49 ILDLSESGLCRLEEVF-RIPSLQQLHLQRNALCVIPQ-DFFQLL-PNLT----WLDLRYN 101
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++ LP I + L TL N I LP +G ++TL+ + L+ P ++Q
Sbjct: 102 RIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPLEFPPQLVVQ 158
>AL590105-5|CAI13016.1| 383|Homo sapiens novel protein protein.
Length = 383
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 7/117 (5%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
+LDLS + + +L F R+ +L +LHL N L V D+ LL P +T LDL N
Sbjct: 49 ILDLSESGLCRLEEVF-RIPSLQQLHLQRNALCVIPQ-DFFQLL-PNLT----WLDLRYN 101
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++ LP I + L TL N I LP +G ++TL+ + L+ P ++Q
Sbjct: 102 RIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPLEFPPQLVVQ 158
>AK098652-1|BAC05366.1| 383|Homo sapiens protein ( Homo sapiens
cDNA FLJ25786 fis, clone TST06852. ).
Length = 383
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 7/117 (5%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
+LDLS + + +L F R+ +L +LHL N L V D+ LL P +T LDL N
Sbjct: 49 ILDLSESGLCRLEEVF-RIPSLQQLHLQRNALCVIPQ-DFFQLL-PNLT----WLDLRYN 101
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++ LP I + L TL N I LP +G ++TL+ + L+ P ++Q
Sbjct: 102 RIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPLEFPPQLVVQ 158
>AB051461-1|BAB21765.1| 538|Homo sapiens KIAA1674 protein protein.
Length = 538
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 7/117 (5%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
+LDLS + + +L F R+ +L +LHL N L V D+ LL P +T LDL N
Sbjct: 57 ILDLSESGLCRLEEVF-RIPSLQQLHLQRNALCVIPQ-DFFQLL-PNLT----WLDLRYN 109
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 291
++ LP I + L TL N I LP +G ++TL+ + L+ P ++Q
Sbjct: 110 RIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPLEFPPQLVVQ 166
>BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein.
Length = 529
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 9/126 (7%)
Query: 147 PRTLQSLYL--SGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
P Q +YL S L F +IL LK+L +L L NN I+++P E ++ L +A N
Sbjct: 342 PLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFN 401
Query: 205 QLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA 264
+ V + G L+ LD++ N+L +P I KL L L + N +S P
Sbjct: 402 LITVLPI-------GLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPH 454
Query: 265 TIGRIS 270
I +++
Sbjct: 455 GILKLN 460
Score = 44.8 bits (101), Expect = 6e-04
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 211
+L L G + N L L L+LS N++ P E + NL L L NN ++ +
Sbjct: 326 ALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNP--IKEI 383
Query: 212 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
Q + L++ + N + LP ++ L L L + N ++ +P I ++ +
Sbjct: 384 PS-----EIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRS 438
Query: 272 LRYFTISSNELQSLPCSLMQCRLEYIDISSN 302
L T+ NEL P +++ L I +N
Sbjct: 439 LEKLTVDGNELSFFPHGILKLNLTKIQFENN 469
Score = 41.1 bits (92), Expect = 0.007
Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L++L L +N + +P I +LE L N+I+ LP + +S L +S NEL
Sbjct: 368 KNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELT 427
Query: 284 SLPCSLMQCR-LEYIDISSNK 303
+P + + R LE + + N+
Sbjct: 428 FIPNEIQKLRSLEKLTVDGNE 448
>AY358298-1|AAQ88665.1| 598|Homo sapiens CSRV314 protein.
Length = 598
Score = 45.6 bits (103), Expect = 3e-04
Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 18/177 (10%)
Query: 133 LVISDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGR 192
+ + D S F GLP LQ L LS ++ + R L L +LDLS+N + L P
Sbjct: 64 ITMLDASSFA--GLPG-LQLLDLSQNQIASLR-----LPRLLLLDLSHNSLLALEPGILD 115
Query: 193 MANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTL 252
AN+ L LA LG++ + + + + L LD++ N+L +P I L L L
Sbjct: 116 TANVEALRLAG--LGLQQLDEGLF----SRLRNLHDLDVSDNQLERVPPVIRGLRGLTRL 169
Query: 253 K-ANDNMISRL-PATIGRISTLRYFTISSNELQSLPCSL--MQCRLEYIDISSNKFD 305
+ A + I++L P + ++ L+ +S+ LQ+LP L + RL + + N F+
Sbjct: 170 RLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFN 226
>AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich
repeat protein SHOC-2 (Ras-binding protein Sur-8)
protein.
Length = 506
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 9/126 (7%)
Query: 147 PRTLQSLYL--SGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
P Q +YL S L F +IL LK+L +L L NN I+++P E ++ L +A N
Sbjct: 342 PLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFN 401
Query: 205 QLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA 264
+ V + G L+ LD++ N+L +P I KL L L + N +S P
Sbjct: 402 LITVLPI-------GLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPH 454
Query: 265 TIGRIS 270
I +++
Sbjct: 455 GILKLN 460
Score = 44.8 bits (101), Expect = 6e-04
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 211
+L L G + N L L L+LS N++ P E + NL L L NN ++ +
Sbjct: 326 ALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNP--IKEI 383
Query: 212 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
Q + L++ + N + LP ++ L L L + N ++ +P I ++ +
Sbjct: 384 PS-----EIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRS 438
Query: 272 LRYFTISSNELQSLPCSLMQCRLEYIDISSN 302
L T+ NEL P +++ L I +N
Sbjct: 439 LEKLTVDGNELSFFPHGILKLNLTKIQFENN 469
Score = 41.1 bits (92), Expect = 0.007
Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L++L L +N + +P I +LE L N+I+ LP + +S L +S NEL
Sbjct: 368 KNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELT 427
Query: 284 SLPCSLMQCR-LEYIDISSNK 303
+P + + R LE + + N+
Sbjct: 428 FIPNEIQKLRSLEKLTVDGNE 448
>AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich
repeat protein SHOC-2 (Ras-binding protein Sur-8)
protein.
Length = 506
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 9/126 (7%)
Query: 147 PRTLQSLYL--SGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
P Q +YL S L F +IL LK+L +L L NN I+++P E ++ L +A N
Sbjct: 342 PLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFN 401
Query: 205 QLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPA 264
+ V + G L+ LD++ N+L +P I KL L L + N +S P
Sbjct: 402 LITVLPI-------GLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPH 454
Query: 265 TIGRIS 270
I +++
Sbjct: 455 GILKLN 460
Score = 44.8 bits (101), Expect = 6e-04
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Query: 152 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 211
+L L G + N L L L+LS N++ P E + NL L L NN ++ +
Sbjct: 326 ALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNP--IKEI 383
Query: 212 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 271
Q + L++ + N + LP ++ L L L + N ++ +P I ++ +
Sbjct: 384 PS-----EIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRS 438
Query: 272 LRYFTISSNELQSLPCSLMQCRLEYIDISSN 302
L T+ NEL P +++ L I +N
Sbjct: 439 LEKLTVDGNELSFFPHGILKLNLTKIQFENN 469
Score = 41.1 bits (92), Expect = 0.007
Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K L++L L +N + +P I +LE L N+I+ LP + +S L +S NEL
Sbjct: 368 KNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELT 427
Query: 284 SLPCSLMQCR-LEYIDISSNK 303
+P + + R LE + + N+
Sbjct: 428 FIPNEIQKLRSLEKLTVDGNE 448
>X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin
glycoprotein protein.
Length = 440
Score = 45.2 bits (102), Expect = 4e-04
Identities = 46/186 (24%), Positives = 87/186 (46%), Gaps = 24/186 (12%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + L LS + + +L LD+SNN +E LP R +L + ANN
Sbjct: 52 GLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPR--SLWNMSAANN 109
Query: 205 QLGVRGVVD--WRW---------------LLGPQITKTLKLLDLTSNKLGHLPKAIWKLE 247
+ + D ++W +L ++L++L+L+SNKL +P +
Sbjct: 110 NIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKL 169
Query: 248 KLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNKF- 304
+V L +N+++ LP T+ ++ L + + +N+ +P +L+ I + +N++
Sbjct: 170 HIVDL-SNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWS 228
Query: 305 -DNKQN 309
D+KQN
Sbjct: 229 CDHKQN 234
>X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin
glycoprotein protein.
Length = 433
Score = 45.2 bits (102), Expect = 4e-04
Identities = 46/186 (24%), Positives = 87/186 (46%), Gaps = 24/186 (12%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + L LS + + +L LD+SNN +E LP R +L + ANN
Sbjct: 45 GLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPR--SLWNMSAANN 102
Query: 205 QLGVRGVVD--WRW---------------LLGPQITKTLKLLDLTSNKLGHLPKAIWKLE 247
+ + D ++W +L ++L++L+L+SNKL +P +
Sbjct: 103 NIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKL 162
Query: 248 KLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNKF- 304
+V L +N+++ LP T+ ++ L + + +N+ +P +L+ I + +N++
Sbjct: 163 HIVDL-SNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWS 221
Query: 305 -DNKQN 309
D+KQN
Sbjct: 222 CDHKQN 227
>M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin
glycoprotein protein.
Length = 440
Score = 45.2 bits (102), Expect = 4e-04
Identities = 46/186 (24%), Positives = 87/186 (46%), Gaps = 24/186 (12%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + L LS + + +L LD+SNN +E LP R +L + ANN
Sbjct: 52 GLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPR--SLWNMSAANN 109
Query: 205 QLGVRGVVD--WRW---------------LLGPQITKTLKLLDLTSNKLGHLPKAIWKLE 247
+ + D ++W +L ++L++L+L+SNKL +P +
Sbjct: 110 NIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKL 169
Query: 248 KLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNKF- 304
+V L +N+++ LP T+ ++ L + + +N+ +P +L+ I + +N++
Sbjct: 170 HIVDL-SNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWS 228
Query: 305 -DNKQN 309
D+KQN
Sbjct: 229 CDHKQN 234
>BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein.
Length = 723
Score = 45.2 bits (102), Expect = 4e-04
Identities = 49/164 (29%), Positives = 78/164 (47%), Gaps = 14/164 (8%)
Query: 148 RTLQSLYLSGLKLCNFRRDIL--LLKH--LAVLDLSNNEIEKLPPE-FGRMANLSELHLA 202
R L SL L L L + L L++H L VLDL +N + +LP F + NL L+ +
Sbjct: 281 RILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNAS 340
Query: 203 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMIS 260
N L G + L+LL LT+N L +P + L L L+ +N +
Sbjct: 341 ANSLESLPSA----CTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLH-LRILRLANNQLQ 395
Query: 261 RLPAT-IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 302
PA+ + ++ L +S N+L+++P ++ C RL + SN
Sbjct: 396 TFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSN 439
Score = 44.0 bits (99), Expect = 0.001
Identities = 39/135 (28%), Positives = 64/135 (47%), Gaps = 10/135 (7%)
Query: 172 HLAVLDLSNNEIEKLPPEFGRMANLSEL---HLANNQLGVRGVVDWRWLLGPQITKTLKL 228
+L L+ S N +E LP +LS L +L NN L + + L+G L++
Sbjct: 333 NLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPV---LVGHL---HLRI 386
Query: 229 LDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 287
L L +N+L P + + KLE+L L + N + +P TI L SN + P
Sbjct: 387 LRLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPE 446
Query: 288 SLMQCRLEYIDISSN 302
L +++++D+S N
Sbjct: 447 ILQLPQIQFVDLSCN 461
Score = 40.7 bits (91), Expect = 0.009
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 226 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 285
LK L+L+ NKLG P + ++ L L + N LP+ IG + L+ + N L +L
Sbjct: 39 LKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTL 98
Query: 286 PCSLMQC-RLEYIDISSNKF 304
P L +L + IS N F
Sbjct: 99 PEELGNLQQLSSLGISFNNF 118
Score = 35.1 bits (77), Expect = 0.45
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
Query: 224 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 283
K +++LD++ N L +P I L L N + LP + I L + N L
Sbjct: 263 KKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNLPTLVEHI-PLEVLDLQHNALT 321
Query: 284 SLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 315
LP +L L Y++ S+N ++ + T ++
Sbjct: 322 RLPDTLFSKALNLRYLNASANSLESLPSACTGEE 355
>BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin
glycoprotein protein.
Length = 440
Score = 45.2 bits (102), Expect = 4e-04
Identities = 46/186 (24%), Positives = 87/186 (46%), Gaps = 24/186 (12%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + L LS + + +L LD+SNN +E LP R +L + ANN
Sbjct: 52 GLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPR--SLWNMSAANN 109
Query: 205 QLGVRGVVD--WRW---------------LLGPQITKTLKLLDLTSNKLGHLPKAIWKLE 247
+ + D ++W +L ++L++L+L+SNKL +P +
Sbjct: 110 NIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKL 169
Query: 248 KLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNKF- 304
+V L +N+++ LP T+ ++ L + + +N+ +P +L+ I + +N++
Sbjct: 170 HIVDL-SNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWS 228
Query: 305 -DNKQN 309
D+KQN
Sbjct: 229 CDHKQN 234
>AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein.
Length = 713
Score = 45.2 bits (102), Expect = 4e-04
Identities = 43/150 (28%), Positives = 79/150 (52%), Gaps = 11/150 (7%)
Query: 139 SQFPAKGLPRTLQSLYLSGLKLCNF-RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANL 196
S + +GL ++L+SL +L RR + + L LDL+ N ++++ P +F M +L
Sbjct: 229 SDYALEGL-QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHL 287
Query: 197 SELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN-KLGHL-PKAIWKLEKLVTLKA 254
EL L NN + + + + P++TK LD+T+N +L + P+A L ++ TL
Sbjct: 288 KELGL-NNMEELVSIDKFALVNLPELTK----LDITNNPRLSFIHPRAFHHLPQMETLML 342
Query: 255 NDNMISRL-PATIGRISTLRYFTISSNELQ 283
N+N +S L T+ + L+ + N ++
Sbjct: 343 NNNALSALHQQTVESLPNLQEVGLHGNPIR 372
Score = 35.9 bits (79), Expect = 0.26
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 10/131 (7%)
Query: 179 SNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGH 238
SN+ + E G +ANL+EL L+ N D+ L PQ+ L L N+L
Sbjct: 78 SNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHAL--PQLLS----LHLEENQLTR 131
Query: 239 L-PKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCSLMQC--RL 294
L + L L L N N + R+ P +S L ++SN L+++ + L
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 295 EYIDISSNKFD 305
E + I NK D
Sbjct: 192 EILMIGGNKVD 202
>AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat
neuronal 5 protein.
Length = 713
Score = 45.2 bits (102), Expect = 4e-04
Identities = 43/150 (28%), Positives = 79/150 (52%), Gaps = 11/150 (7%)
Query: 139 SQFPAKGLPRTLQSLYLSGLKLCNF-RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANL 196
S + +GL ++L+SL +L RR + + L LDL+ N ++++ P +F M +L
Sbjct: 229 SDYALEGL-QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHL 287
Query: 197 SELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN-KLGHL-PKAIWKLEKLVTLKA 254
EL L NN + + + + P++TK LD+T+N +L + P+A L ++ TL
Sbjct: 288 KELGL-NNMEELVSIDKFALVNLPELTK----LDITNNPRLSFIHPRAFHHLPQMETLML 342
Query: 255 NDNMISRL-PATIGRISTLRYFTISSNELQ 283
N+N +S L T+ + L+ + N ++
Sbjct: 343 NNNALSALHQQTVESLPNLQEVGLHGNPIR 372
Score = 35.9 bits (79), Expect = 0.26
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 10/131 (7%)
Query: 179 SNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGH 238
SN+ + E G +ANL+EL L+ N D+ L PQ+ L L N+L
Sbjct: 78 SNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHAL--PQLLS----LHLEENQLTR 131
Query: 239 L-PKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCSLMQC--RL 294
L + L L L N N + R+ P +S L ++SN L+++ + L
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 295 EYIDISSNKFD 305
E + I NK D
Sbjct: 192 EILMIGGNKVD 202
>AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 45.2 bits (102), Expect = 4e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 212 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 264
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 273
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 265 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 310
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/122 (34%), Positives = 59/122 (48%), Gaps = 13/122 (10%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLA 202
+G PR L L+ L+ F L+ L L LS N + +P + F + +L L L
Sbjct: 24 RGAPRDLSMNNLTELQPGLFHH----LRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQ 79
Query: 203 NNQLGVRGV-VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR 261
NNQLG G+ + W L +L+ LDL NKL P AI L +L L ++N I
Sbjct: 80 NNQLG--GIPAEALWEL-----PSLQSLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 132
Query: 262 LP 263
+P
Sbjct: 133 IP 134
Score = 37.1 bits (82), Expect = 0.11
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 12/159 (7%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMAN--LSELHLANNQL 206
+LQSL L+ KL F I L L L NN I+ +P E M N L +H +N +
Sbjct: 96 SLQSLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP-EKAFMGNPLLQTIHFYDNPI 154
Query: 207 GVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 266
G +++L P++ TL L + K LE L +A I LP+ +
Sbjct: 155 QFVGRSAFQYL--PKL-HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAG---IRLLPSGM 208
Query: 267 -GRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
++ LR +S N+++ LP SL +C +LE I + N+
Sbjct: 209 CQQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGLQHNR 246
>AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin
glycoprotein variant protein.
Length = 440
Score = 45.2 bits (102), Expect = 4e-04
Identities = 46/186 (24%), Positives = 87/186 (46%), Gaps = 24/186 (12%)
Query: 145 GLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
GL + L LS + + +L LD+SNN +E LP R +L + ANN
Sbjct: 52 GLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPR--SLWNMSAANN 109
Query: 205 QLGVRGVVD--WRW---------------LLGPQITKTLKLLDLTSNKLGHLPKAIWKLE 247
+ + D ++W +L ++L++L+L+SNKL +P +
Sbjct: 110 NIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKL 169
Query: 248 KLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNKF- 304
+V L +N+++ LP T+ ++ L + + +N+ +P +L+ I + +N++
Sbjct: 170 HIVDL-SNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWS 228
Query: 305 -DNKQN 309
D+KQN
Sbjct: 229 CDHKQN 234
>AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens
cDNA FLJ38291 fis, clone FCBBF3009069, weakly similar to
Homo sapiens HT017 mRNA. ).
Length = 370
Score = 45.2 bits (102), Expect = 4e-04
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 12/141 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 228
L L LDLSNN +++LP FG + NL+EL L NN + +D R LL + + L+
Sbjct: 91 LSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSI---RTLD-RDLL--RHSPLLRH 144
Query: 229 LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 286
LDL+ N L LP ++ L L +L N + L T ++ L+ + N +
Sbjct: 145 LDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWE-CD 203
Query: 287 CSLMQCR--LEYIDISSNKFD 305
C+L + + +E+ + D
Sbjct: 204 CNLREFKHWMEWFSYRGGRLD 224
>AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 45.2 bits (102), Expect = 4e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 229
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 212 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 264
Query: 230 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 273
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 265 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 310
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/122 (34%), Positives = 59/122 (48%), Gaps = 13/122 (10%)
Query: 144 KGLPRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLA 202
+G PR L L+ L+ F L+ L L LS N + +P + F + +L L L
Sbjct: 24 RGAPRDLSMNNLTELQPGLFHH----LRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQ 79
Query: 203 NNQLGVRGV-VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR 261
NNQLG G+ + W L +L+ LDL NKL P AI L +L L ++N I
Sbjct: 80 NNQLG--GIPAEALWEL-----PSLQSLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 132
Query: 262 LP 263
+P
Sbjct: 133 IP 134
Score = 37.1 bits (82), Expect = 0.11
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 12/159 (7%)
Query: 149 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMAN--LSELHLANNQL 206
+LQSL L+ KL F I L L L NN I+ +P E M N L +H +N +
Sbjct: 96 SLQSLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP-EKAFMGNPLLQTIHFYDNPI 154
Query: 207 GVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 266
G +++L P++ TL L + K LE L +A I LP+ +
Sbjct: 155 QFVGRSAFQYL--PKL-HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAG---IRLLPSGM 208
Query: 267 -GRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 303
++ LR +S N+++ LP SL +C +LE I + N+
Sbjct: 209 CQQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGLQHNR 246
>AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on
chromosome 1 protein protein.
Length = 713
Score = 45.2 bits (102), Expect = 4e-04
Identities = 43/150 (28%), Positives = 79/150 (52%), Gaps = 11/150 (7%)
Query: 139 SQFPAKGLPRTLQSLYLSGLKLCNF-RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANL 196
S + +GL ++L+SL +L RR + + L LDL+ N ++++ P +F M +L
Sbjct: 229 SDYALEGL-QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHL 287
Query: 197 SELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN-KLGHL-PKAIWKLEKLVTLKA 254
EL L NN + + + + P++TK LD+T+N +L + P+A L ++ TL
Sbjct: 288 KELGL-NNMEELVSIDKFALVNLPELTK----LDITNNPRLSFIHPRAFHHLPQMETLML 342
Query: 255 NDNMISRL-PATIGRISTLRYFTISSNELQ 283
N+N +S L T+ + L+ + N ++
Sbjct: 343 NNNALSALHQQTVESLPNLQEVGLHGNPIR 372
Score = 35.9 bits (79), Expect = 0.26
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 10/131 (7%)
Query: 179 SNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGH 238
SN+ + E G +ANL+EL L+ N D+ L PQ+ L L N+L
Sbjct: 78 SNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHAL--PQLLS----LHLEENQLTR 131
Query: 239 L-PKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCSLMQC--RL 294
L + L L L N N + R+ P +S L ++SN L+++ + L
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 295 EYIDISSNKFD 305
E + I NK D
Sbjct: 192 EILMIGGNKVD 202
>BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 44.4 bits (100), Expect = 7e-04
Identities = 40/128 (31%), Positives = 70/128 (54%), Gaps = 10/128 (7%)
Query: 139 SQFPAKGLPRTLQSLYLSGLKLCNF-RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANL 196
S + +GL ++L+SL +L RR + + L LDL+ N ++++ P +F M +L
Sbjct: 229 SDYALEGL-QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHL 287
Query: 197 SELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN-KLGHL-PKAIWKLEKLVTLKA 254
EL L NN + + + + P++TK LD+T+N +L + P+A L ++ TL
Sbjct: 288 KELGL-NNMEELVSIDKFALVNLPELTK----LDITNNPRLSFIHPRAFHHLPQMETLML 342
Query: 255 NDNMISRL 262
N+N +S L
Sbjct: 343 NNNALSAL 350
Score = 35.9 bits (79), Expect = 0.26
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 10/131 (7%)
Query: 179 SNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGH 238
SN+ + E G +ANL+EL L+ N D+ L PQ+ L L N+L
Sbjct: 78 SNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHAL--PQLLS----LHLEENQLTR 131
Query: 239 L-PKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCSLMQC--RL 294
L + L L L N N + R+ P +S L ++SN L+++ + L
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 295 EYIDISSNKFD 305
E + I NK D
Sbjct: 192 EILMIGGNKVD 202
>BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 44.4 bits (100), Expect = 7e-04
Identities = 40/128 (31%), Positives = 70/128 (54%), Gaps = 10/128 (7%)
Query: 139 SQFPAKGLPRTLQSLYLSGLKLCNF-RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANL 196
S + +GL ++L+SL +L RR + + L LDL+ N ++++ P +F M +L
Sbjct: 229 SDYALEGL-QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHL 287
Query: 197 SELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN-KLGHL-PKAIWKLEKLVTLKA 254
EL L NN + + + + P++TK LD+T+N +L + P+A L ++ TL
Sbjct: 288 KELGL-NNMEELVSIDKFALVNLPELTK----LDITNNPRLSFIHPRAFHHLPQMETLML 342
Query: 255 NDNMISRL 262
N+N +S L
Sbjct: 343 NNNALSAL 350
Score = 35.9 bits (79), Expect = 0.26
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 10/131 (7%)
Query: 179 SNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGH 238
SN+ + E G +ANL+EL L+ N D+ L PQ+ L L N+L
Sbjct: 78 SNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHAL--PQLLS----LHLEENQLTR 131
Query: 239 L-PKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCSLMQC--RL 294
L + L L L N N + R+ P +S L ++SN L+++ + L
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNL 191
Query: 295 EYIDISSNKFD 305
E + I NK D
Sbjct: 192 EILMIGGNKVD 202
>BC030547-1|AAH30547.1| 647|Homo sapiens hypothetical protein
DKFZp434K1815 protein.
Length = 647
Score = 44.4 bits (100), Expect = 7e-04
Identities = 29/61 (47%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Query: 150 LQSLYLSGLKLCNFRRDILLL---KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
++SL LSGL+L + D LL L LDLSNN +E LP G +++L L ANNQL
Sbjct: 23 IRSLDLSGLELLSEHLDPKLLCRLTQLQELDLSNNHLETLPDNLG-LSHLRVLRCANNQL 81
Query: 207 G 207
G
Sbjct: 82 G 82
>Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein.
Length = 845
Score = 44.0 bits (99), Expect = 0.001
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 9/140 (6%)
Query: 150 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 207
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 266
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 267 GRISTLRYFTISSNELQSLP 286
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 44.0 bits (99), Expect = 0.001
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 9/140 (6%)
Query: 150 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 207
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 266
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 267 GRISTLRYFTISSNELQSLP 286
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 44.0 bits (99), Expect = 0.001
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 9/140 (6%)
Query: 150 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 207
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 266
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 267 GRISTLRYFTISSNELQSLP 286
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 44.0 bits (99), Expect = 0.001
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 14/152 (9%)
Query: 157 GLKLCNFRRDILLLKHLAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQLGVRGVVDWR 215
G+ L F D L +H L L NN++EK+ P E R+ L L+L NN+L RG+ +
Sbjct: 132 GIDLREFPGD--LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKA 189
Query: 216 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRY 274
+ + L L L +NKL P+ + L+++ N ++++ T G+ LR
Sbjct: 190 F----EHLTNLNYLYLANNKLTLAPRFL--PNALISVDFAANYLTKIYGLTFGQKPNLRS 243
Query: 275 FTISSNEL--QSLPCSLM--QCRLEYIDISSN 302
+ +N+L LP ++ +E + +SSN
Sbjct: 244 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSN 275
Score = 36.3 bits (80), Expect = 0.20
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 32/131 (24%)
Query: 176 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
L L NN++EK+PP F +++L EL+L NN LT
Sbjct: 291 LHLKNNKLEKIPPGAFSELSSLRELYLQNNY-------------------------LTDE 325
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--C 292
L + + WKL L L + N +SR+PA + R L + + N ++S+ +++
Sbjct: 326 GLDN--ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLH--LEKNAIRSVDANVLTPIR 381
Query: 293 RLEYIDISSNK 303
LEY+ + SN+
Sbjct: 382 SLEYLLLHSNQ 392
Score = 35.5 bits (78), Expect = 0.34
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 17/124 (13%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG--VRGVVDWRWLLGPQITKTLK 227
L+ L LDLS N + LPP G N+ L + N+L RG L G L+
Sbjct: 477 LRLLRSLDLSGNRLHTLPP--GLPRNVHVLKVKRNELAALARGA-----LAG---MAQLR 526
Query: 228 LLDLTSNKLGHL---PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
L LTSN+L P+A L L L N ++ +P G +L Y + +N++ +
Sbjct: 527 ELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE--GLPESLEYLYLQNNKISA 584
Query: 285 LPCS 288
+P +
Sbjct: 585 VPAN 588
>AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein.
Length = 733
Score = 44.0 bits (99), Expect = 0.001
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 9/140 (6%)
Query: 150 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 207
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 266
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 267 GRISTLRYFTISSNELQSLP 286
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein.
Length = 642
Score = 44.0 bits (99), Expect = 0.001
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 14/152 (9%)
Query: 157 GLKLCNFRRDILLLKHLAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQLGVRGVVDWR 215
G+ L F D L +H L L NN++EK+ P E R+ L L+L NN+L RG+ +
Sbjct: 113 GIDLREFPGD--LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKA 170
Query: 216 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRY 274
+ + L L L +NKL P+ + L+++ N ++++ T G+ LR
Sbjct: 171 F----EHLTNLNYLYLANNKLTLAPRFL--PNALISVDFAANYLTKIYGLTFGQKPNLRS 224
Query: 275 FTISSNEL--QSLPCSLM--QCRLEYIDISSN 302
+ +N+L LP ++ +E + +SSN
Sbjct: 225 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSN 256
Score = 36.3 bits (80), Expect = 0.20
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 32/131 (24%)
Query: 176 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
L L NN++EK+PP F +++L EL+L NN LT
Sbjct: 272 LHLKNNKLEKIPPGAFSELSSLRELYLQNNY-------------------------LTDE 306
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--C 292
L + + WKL L L + N +SR+PA + R L + + N ++S+ +++
Sbjct: 307 GLDN--ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLH--LEKNAIRSVDANVLTPIR 362
Query: 293 RLEYIDISSNK 303
LEY+ + SN+
Sbjct: 363 SLEYLLLHSNQ 373
Score = 35.5 bits (78), Expect = 0.34
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 17/124 (13%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG--VRGVVDWRWLLGPQITKTLK 227
L+ L LDLS N + LPP G N+ L + N+L RG L G L+
Sbjct: 458 LRLLRSLDLSGNRLHTLPP--GLPRNVHVLKVKRNELAALARGA-----LAG---MAQLR 507
Query: 228 LLDLTSNKLGHL---PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
L LTSN+L P+A L L L N ++ +P G +L Y + +N++ +
Sbjct: 508 ELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE--GLPESLEYLYLQNNKISA 565
Query: 285 LPCS 288
+P +
Sbjct: 566 VPAN 569
>AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein.
Length = 613
Score = 44.0 bits (99), Expect = 0.001
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 14/152 (9%)
Query: 157 GLKLCNFRRDILLLKHLAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQLGVRGVVDWR 215
G+ L F D L +H L L NN++EK+ P E R+ L L+L NN+L RG+ +
Sbjct: 84 GIDLREFPGD--LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKA 141
Query: 216 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRY 274
+ + L L L +NKL P+ + L+++ N ++++ T G+ LR
Sbjct: 142 F----EHLTNLNYLYLANNKLTLAPRFL--PNALISVDFAANYLTKIYGLTFGQKPNLRS 195
Query: 275 FTISSNEL--QSLPCSLM--QCRLEYIDISSN 302
+ +N+L LP ++ +E + +SSN
Sbjct: 196 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSN 227
Score = 36.3 bits (80), Expect = 0.20
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 32/131 (24%)
Query: 176 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
L L NN++EK+PP F +++L EL+L NN LT
Sbjct: 243 LHLKNNKLEKIPPGAFSELSSLRELYLQNNY-------------------------LTDE 277
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--C 292
L + + WKL L L + N +SR+PA + R L + + N ++S+ +++
Sbjct: 278 GLDN--ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLH--LEKNAIRSVDANVLTPIR 333
Query: 293 RLEYIDISSNK 303
LEY+ + SN+
Sbjct: 334 SLEYLLLHSNQ 344
Score = 35.5 bits (78), Expect = 0.34
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 17/124 (13%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG--VRGVVDWRWLLGPQITKTLK 227
L+ L LDLS N + LPP G N+ L + N+L RG L G L+
Sbjct: 429 LRLLRSLDLSGNRLHMLPP--GLPRNVHVLKVKRNELAALARGA-----LAG---MAQLR 478
Query: 228 LLDLTSNKLGHL---PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
L LTSN+L P+A L L L N ++ +P G +L Y + +N++ +
Sbjct: 479 ELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE--GLPESLEYLYLQNNKISA 536
Query: 285 LPCS 288
+P +
Sbjct: 537 VPAN 540
>AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein.
Length = 642
Score = 44.0 bits (99), Expect = 0.001
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 14/152 (9%)
Query: 157 GLKLCNFRRDILLLKHLAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQLGVRGVVDWR 215
G+ L F D L +H L L NN++EK+ P E R+ L L+L NN+L RG+ +
Sbjct: 113 GIDLREFPGD--LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKA 170
Query: 216 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRY 274
+ + L L L +NKL P+ + L+++ N ++++ T G+ LR
Sbjct: 171 F----EHLTNLNYLYLANNKLTLAPRFL--PNALISVDFAANYLTKIYGLTFGQKPNLRS 224
Query: 275 FTISSNEL--QSLPCSLM--QCRLEYIDISSN 302
+ +N+L LP ++ +E + +SSN
Sbjct: 225 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSN 256
Score = 36.3 bits (80), Expect = 0.20
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 32/131 (24%)
Query: 176 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
L L NN++EK+PP F +++L EL+L NN LT
Sbjct: 272 LHLKNNKLEKIPPGAFSELSSLRELYLQNNY-------------------------LTDE 306
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--C 292
L + + WKL L L + N +SR+PA + R L + + N ++S+ +++
Sbjct: 307 GLDN--ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLH--LEKNAIRSVDANVLTPIR 362
Query: 293 RLEYIDISSNK 303
LEY+ + SN+
Sbjct: 363 SLEYLLLHSNQ 373
Score = 36.3 bits (80), Expect = 0.20
Identities = 38/124 (30%), Positives = 58/124 (46%), Gaps = 17/124 (13%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG--VRGVVDWRWLLGPQITKTLK 227
L+ L LDLS N + LPP G N+ L + N+L RG L+G L+
Sbjct: 458 LRLLRSLDLSGNRLHTLPP--GLPRNVHVLKVKRNELAALARGA-----LVG---MAQLR 507
Query: 228 LLDLTSNKLGHL---PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
L LTSN+L P+A L L L N ++ +P G +L Y + +N++ +
Sbjct: 508 ELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE--GLPESLEYLYLQNNKISA 565
Query: 285 LPCS 288
+P +
Sbjct: 566 VPAN 569
>AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 44.0 bits (99), Expect = 0.001
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 14/152 (9%)
Query: 157 GLKLCNFRRDILLLKHLAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQLGVRGVVDWR 215
G+ L F D L +H L L NN++EK+ P E R+ L L+L NN+L RG+ +
Sbjct: 132 GIDLREFPGD--LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKA 189
Query: 216 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRY 274
+ + L L L +NKL P+ + L+++ N ++++ T G+ LR
Sbjct: 190 F----EHLTNLNYLYLANNKLTLAPRFL--PNALISVDFAANYLTKIYGLTFGQKPNLRS 243
Query: 275 FTISSNEL--QSLPCSLM--QCRLEYIDISSN 302
+ +N+L LP ++ +E + +SSN
Sbjct: 244 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSN 275
Score = 36.3 bits (80), Expect = 0.20
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 32/131 (24%)
Query: 176 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
L L NN++EK+PP F +++L EL+L NN LT
Sbjct: 291 LHLKNNKLEKIPPGAFSELSSLRELYLQNNY-------------------------LTDE 325
Query: 235 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--C 292
L + + WKL L L + N +SR+PA + R L + + N ++S+ +++
Sbjct: 326 GLDN--ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLH--LEKNAIRSVDANVLTPIR 381
Query: 293 RLEYIDISSNK 303
LEY+ + SN+
Sbjct: 382 SLEYLLLHSNQ 392
Score = 36.3 bits (80), Expect = 0.20
Identities = 38/124 (30%), Positives = 58/124 (46%), Gaps = 17/124 (13%)
Query: 170 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG--VRGVVDWRWLLGPQITKTLK 227
L+ L LDLS N + LPP G N+ L + N+L RG L+G L+
Sbjct: 477 LRLLRSLDLSGNRLHTLPP--GLPRNVHVLKVKRNELAALARGA-----LVG---MAQLR 526
Query: 228 LLDLTSNKLGHL---PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
L LTSN+L P+A L L L N ++ +P G +L Y + +N++ +
Sbjct: 527 ELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE--GLPESLEYLYLQNNKISA 584
Query: 285 LPCS 288
+P +
Sbjct: 585 VPAN 588
>AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 44.0 bits (99), Expect = 0.001
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 9/140 (6%)
Query: 150 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 207
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 266
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 267 GRISTLRYFTISSNELQSLP 286
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 724
Score = 44.0 bits (99), Expect = 0.001
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 9/140 (6%)
Query: 150 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 207
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 266
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 267 GRISTLRYFTISSNELQSLP 286
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens
cDNA FLJ33696 fis, clone BRAWH2003964, weakly similar to
SLIT PROTEIN PRECURSOR. ).
Length = 724
Score = 44.0 bits (99), Expect = 0.001
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 9/140 (6%)
Query: 150 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 207
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 266
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 267 GRISTLRYFTISSNELQSLP 286
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein.
Length = 572
Score = 44.0 bits (99), Expect = 0.001
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 9/140 (6%)
Query: 150 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 207
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 70 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 129
Query: 208 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 266
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 130 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 183
Query: 267 GRISTLRYFTISSNELQSLP 286
R L + + N L+ +P
Sbjct: 184 FRFVLLTHLDLRGNRLKVMP 203
>BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 13/140 (9%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLK 227
L +L LDLS N++ L PE F + L LHL +N L V + W ++L+
Sbjct: 132 LINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWD-------CRSLE 184
Query: 228 LLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSL 285
LDL++N+L L + L KL L N ++++ A R+S+L + N++ +L
Sbjct: 185 FLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNL 244
Query: 286 PCSLMQC--RLEYIDISSNK 303
C + LE +D++ N+
Sbjct: 245 TCGMEWTWGTLEKLDLTGNE 264
Score = 35.9 bits (79), Expect = 0.26
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 12/164 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 205
R LQ+L+L L + + L LDLS N + L F + L ELHL +NQ
Sbjct: 157 RKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQ 216
Query: 206 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAI-WKLEKLVTLKANDNMISRLPA 264
L + L +L L L NK+ +L + W L L N I +
Sbjct: 217 LTKINFAHFLRL------SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDL 270
Query: 265 TI-GRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNKFD 305
T+ + L+ + +N+L SL ++ L + +S N ++
Sbjct: 271 TVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 314
>BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 13/140 (9%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLK 227
L +L LDLS N++ L PE F + L LHL +N L V + W ++L+
Sbjct: 132 LINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWD-------CRSLE 184
Query: 228 LLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSL 285
LDL++N+L L + L KL L N ++++ A R+S+L + N++ +L
Sbjct: 185 FLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNL 244
Query: 286 PCSLMQC--RLEYIDISSNK 303
C + LE +D++ N+
Sbjct: 245 TCGMEWTWGTLEKLDLTGNE 264
Score = 35.9 bits (79), Expect = 0.26
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 12/164 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 205
R LQ+L+L L + + L LDLS N + L F + L ELHL +NQ
Sbjct: 157 RKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQ 216
Query: 206 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAI-WKLEKLVTLKANDNMISRLPA 264
L + L +L L L NK+ +L + W L L N I +
Sbjct: 217 LTKINFAHFLRL------SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDL 270
Query: 265 TI-GRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNKFD 305
T+ + L+ + +N+L SL ++ L + +S N ++
Sbjct: 271 TVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 314
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 43.6 bits (98), Expect = 0.001
Identities = 44/167 (26%), Positives = 85/167 (50%), Gaps = 15/167 (8%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
LP + L LS +L + + L+ L + L+NNE+E +P AN++ L LA N
Sbjct: 72 LPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGN 131
Query: 205 QLGVRGVVDWRWLLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL 262
+ +V+ +L + ++L+ LDL+SN + L A L+ L L N N ++ +
Sbjct: 132 R-----IVE---ILPEHLKEFQSLETLDLSSNNISELQTAFPALQ-LKYLYLNSNRVTSM 182
Query: 263 -PATIGRI-STLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
P + +TL ++ N + ++P + + +L++++++ NK N
Sbjct: 183 EPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKN 229
Score = 35.5 bits (78), Expect = 0.34
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 14/161 (8%)
Query: 173 LAVLDLSNNEIEKLPPEFGRMAN-LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 231
L L LS N I ++ P+ LSEL L N L +D LG + TL +
Sbjct: 289 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSR---LDDSSFLGLSLLNTLHI--- 342
Query: 232 TSNKLGHLPKAIWK-LEKLVTLKANDNMIS----RLPATIGRISTLRYFTISSNELQSLP 286
+N++ ++ ++ L L TL +N IS + + LR + N ++S+
Sbjct: 343 GNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSIT 402
Query: 287 CSLMQC--RLEYIDISSNKFDNKQNNSTSDQYSPWQFYVGS 325
LE++D+S N + Q N+ S Q ++ +
Sbjct: 403 KKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNT 443
Score = 32.3 bits (70), Expect = 3.2
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 11/131 (8%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
+LD S + +LP ++ L L++N+L L ++L+ + L +N
Sbjct: 57 LLDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHL------QSLREVKLNNN 108
Query: 235 KLGHLPKAIWKLEKLVTLK--ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC 292
+L +P + + +TL A + ++ LP + +L +SSN + L +
Sbjct: 109 ELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPAL 167
Query: 293 RLEYIDISSNK 303
+L+Y+ ++SN+
Sbjct: 168 QLKYLYLNSNR 178
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 43.6 bits (98), Expect = 0.001
Identities = 44/167 (26%), Positives = 85/167 (50%), Gaps = 15/167 (8%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
LP + L LS +L + + L+ L + L+NNE+E +P AN++ L LA N
Sbjct: 72 LPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGN 131
Query: 205 QLGVRGVVDWRWLLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL 262
+ +V+ +L + ++L+ LDL+SN + L A L+ L L N N ++ +
Sbjct: 132 R-----IVE---ILPEHLKEFQSLETLDLSSNNISELQTAFPALQ-LKYLYLNSNRVTSM 182
Query: 263 -PATIGRI-STLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
P + +TL ++ N + ++P + + +L++++++ NK N
Sbjct: 183 EPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKN 229
Score = 35.5 bits (78), Expect = 0.34
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 14/161 (8%)
Query: 173 LAVLDLSNNEIEKLPPEFGRMAN-LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 231
L L LS N I ++ P+ LSEL L N L +D LG + TL +
Sbjct: 289 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSR---LDDSSFLGLSLLNTLHI--- 342
Query: 232 TSNKLGHLPKAIWK-LEKLVTLKANDNMIS----RLPATIGRISTLRYFTISSNELQSLP 286
+N++ ++ ++ L L TL +N IS + + LR + N ++S+
Sbjct: 343 GNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSIT 402
Query: 287 CSLMQC--RLEYIDISSNKFDNKQNNSTSDQYSPWQFYVGS 325
LE++D+S N + Q N+ S Q ++ +
Sbjct: 403 KKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNT 443
Score = 32.3 bits (70), Expect = 3.2
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 11/131 (8%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
+LD S + +LP ++ L L++N+L L ++L+ + L +N
Sbjct: 57 LLDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHL------QSLREVKLNNN 108
Query: 235 KLGHLPKAIWKLEKLVTLK--ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC 292
+L +P + + +TL A + ++ LP + +L +SSN + L +
Sbjct: 109 ELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPAL 167
Query: 293 RLEYIDISSNK 303
+L+Y+ ++SN+
Sbjct: 168 QLKYLYLNSNR 178
>BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein.
Length = 522
Score = 43.6 bits (98), Expect = 0.001
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 15/144 (10%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEF--GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
L + + LDLS N I L E+ A L+ L L +N + + T L
Sbjct: 66 LFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSF------STTPNL 119
Query: 227 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQS 284
K LDL+SNKL + A++ +L+ L L +N IS L P+ G +S L+ +S N L
Sbjct: 120 KCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQ 179
Query: 285 LPCSLMQCR-----LEYIDISSNK 303
P L R L ++D+S N+
Sbjct: 180 FPMDLYVGRFKLAELMFLDVSYNR 203
>BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with
Ig-like domain 2 protein.
Length = 522
Score = 43.6 bits (98), Expect = 0.001
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 15/144 (10%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEF--GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
L + + LDLS N I L E+ A L+ L L +N + + T L
Sbjct: 66 LFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSF------STTPNL 119
Query: 227 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQS 284
K LDL+SNKL + A++ +L+ L L +N IS L P+ G +S L+ +S N L
Sbjct: 120 KCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQ 179
Query: 285 LPCSLMQCR-----LEYIDISSNK 303
P L R L ++D+S N+
Sbjct: 180 FPMDLYVGRFKLAELMFLDVSYNR 203
>BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7
protein.
Length = 1049
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/112 (33%), Positives = 62/112 (55%), Gaps = 10/112 (8%)
Query: 145 GLPRTLQSLYLS--GLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMA-NLSELHL 201
G+P L++L L+ GLK ++++ + LK+L LDLS+N++ +P + +L L L
Sbjct: 672 GMPPNLKNLSLAKNGLKSFSWKK-LQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLIL 730
Query: 202 ANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
NNQ +R + ++ L Q L+ LDL+SNK+ + K + L LK
Sbjct: 731 KNNQ--IRSLT--KYFL--QDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLK 776
Score = 40.7 bits (91), Expect = 0.009
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 190 FGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP-KAIWKL 246
F + L EL ++ N L GV D + LK L L N L K + L
Sbjct: 646 FKNLLKLEELDISKNSLSFLPSGVFDG-------MPPNLKNLSLAKNGLKSFSWKKLQCL 698
Query: 247 EKLVTLKANDNMISRLPATIGRIS-TLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNK 303
+ L TL + N ++ +P + S +L+ + +N+++SL +Q +L Y+D+SSNK
Sbjct: 699 KNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNK 758
Query: 304 FDNKQNNS 311
Q S
Sbjct: 759 IQMIQKTS 766
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 43.6 bits (98), Expect = 0.001
Identities = 44/167 (26%), Positives = 85/167 (50%), Gaps = 15/167 (8%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
LP + L LS +L + + L+ L + L+NNE+E +P AN++ L LA N
Sbjct: 72 LPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGN 131
Query: 205 QLGVRGVVDWRWLLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL 262
+ +V+ +L + ++L+ LDL+SN + L A L+ L L N N ++ +
Sbjct: 132 R-----IVE---ILPEHLKEFQSLETLDLSSNNISELQTAFPALQ-LKYLYLNSNRVTSM 182
Query: 263 -PATIGRI-STLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
P + +TL ++ N + ++P + + +L++++++ NK N
Sbjct: 183 EPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKN 229
Score = 35.5 bits (78), Expect = 0.34
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 14/161 (8%)
Query: 173 LAVLDLSNNEIEKLPPEFGRMAN-LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 231
L L LS N I ++ P+ LSEL L N L +D LG + TL +
Sbjct: 289 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSR---LDDSSFLGLSLLNTLHI--- 342
Query: 232 TSNKLGHLPKAIWK-LEKLVTLKANDNMIS----RLPATIGRISTLRYFTISSNELQSLP 286
+N++ ++ ++ L L TL +N IS + + LR + N ++S+
Sbjct: 343 GNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSIT 402
Query: 287 CSLMQC--RLEYIDISSNKFDNKQNNSTSDQYSPWQFYVGS 325
LE++D+S N + Q N+ S Q ++ +
Sbjct: 403 KKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNT 443
Score = 32.3 bits (70), Expect = 3.2
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 11/131 (8%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
+LD S + +LP ++ L L++N+L L ++L+ + L +N
Sbjct: 57 LLDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHL------QSLREVKLNNN 108
Query: 235 KLGHLPKAIWKLEKLVTLK--ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC 292
+L +P + + +TL A + ++ LP + +L +SSN + L +
Sbjct: 109 ELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPAL 167
Query: 293 RLEYIDISSNK 303
+L+Y+ ++SN+
Sbjct: 168 QLKYLYLNSNR 178
>AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor
protein.
Length = 522
Score = 43.6 bits (98), Expect = 0.001
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 15/144 (10%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEF--GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
L + + LDLS N I L E+ A L+ L L +N + + T L
Sbjct: 66 LFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSF------STTPNL 119
Query: 227 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQS 284
K LDL+SNKL + A++ +L+ L L +N IS L P+ G +S L+ +S N L
Sbjct: 120 KCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQ 179
Query: 285 LPCSLMQCR-----LEYIDISSNK 303
P L R L ++D+S N+
Sbjct: 180 FPMDLYVGRFKLAELMFLDVSYNR 203
>AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein.
Length = 1049
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/112 (33%), Positives = 62/112 (55%), Gaps = 10/112 (8%)
Query: 145 GLPRTLQSLYLS--GLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMA-NLSELHL 201
G+P L++L L+ GLK ++++ + LK+L LDLS+N++ +P + +L L L
Sbjct: 672 GMPPNLKNLSLAKNGLKSFSWKK-LQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLIL 730
Query: 202 ANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
NNQ +R + ++ L Q L+ LDL+SNK+ + K + L LK
Sbjct: 731 KNNQ--IRSLT--KYFL--QDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLK 776
Score = 40.7 bits (91), Expect = 0.009
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 190 FGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP-KAIWKL 246
F + L EL ++ N L GV D + LK L L N L K + L
Sbjct: 646 FKNLLKLEELDISKNSLSFLPSGVFDG-------MPPNLKNLSLAKNGLKSFSWKKLQCL 698
Query: 247 EKLVTLKANDNMISRLPATIGRIS-TLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNK 303
+ L TL + N ++ +P + S +L+ + +N+++SL +Q +L Y+D+SSNK
Sbjct: 699 KNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNK 758
Query: 304 FDNKQNNS 311
Q S
Sbjct: 759 IQMIQKTS 766
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 43.6 bits (98), Expect = 0.001
Identities = 44/167 (26%), Positives = 85/167 (50%), Gaps = 15/167 (8%)
Query: 146 LPRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 204
LP + L LS +L + + L+ L + L+NNE+E +P AN++ L LA N
Sbjct: 72 LPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGN 131
Query: 205 QLGVRGVVDWRWLLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL 262
+ +V+ +L + ++L+ LDL+SN + L A L+ L L N N ++ +
Sbjct: 132 R-----IVE---ILPEHLKEFQSLETLDLSSNNISELQTAFPALQ-LKYLYLNSNRVTSM 182
Query: 263 -PATIGRI-STLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 306
P + +TL ++ N + ++P + + +L++++++ NK N
Sbjct: 183 EPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKN 229
Score = 35.5 bits (78), Expect = 0.34
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 14/161 (8%)
Query: 173 LAVLDLSNNEIEKLPPEFGRMAN-LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 231
L L LS N I ++ P+ LSEL L N L +D LG + TL +
Sbjct: 289 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSR---LDDSSFLGLSLLNTLHI--- 342
Query: 232 TSNKLGHLPKAIWK-LEKLVTLKANDNMIS----RLPATIGRISTLRYFTISSNELQSLP 286
+N++ ++ ++ L L TL +N IS + + LR + N ++S+
Sbjct: 343 GNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSIT 402
Query: 287 CSLMQC--RLEYIDISSNKFDNKQNNSTSDQYSPWQFYVGS 325
LE++D+S N + Q N+ S Q ++ +
Sbjct: 403 KKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNT 443
Score = 32.3 bits (70), Expect = 3.2
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 11/131 (8%)
Query: 175 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 234
+LD S + +LP ++ L L++N+L L ++L+ + L +N
Sbjct: 57 LLDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHL------QSLREVKLNNN 108
Query: 235 KLGHLPKAIWKLEKLVTLK--ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC 292
+L +P + + +TL A + ++ LP + +L +SSN + L +
Sbjct: 109 ELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPAL 167
Query: 293 RLEYIDISSNK 303
+L+Y+ ++SN+
Sbjct: 168 QLKYLYLNSNR 178
>AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein
AMIGO2 protein.
Length = 522
Score = 43.6 bits (98), Expect = 0.001
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 15/144 (10%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEF--GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
L + + LDLS N I L E+ A L+ L L +N + + T L
Sbjct: 66 LFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSF------STTPNL 119
Query: 227 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQS 284
K LDL+SNKL + A++ +L+ L L +N IS L P+ G +S L+ +S N L
Sbjct: 120 KCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQ 179
Query: 285 LPCSLMQCR-----LEYIDISSNK 303
P L R L ++D+S N+
Sbjct: 180 FPMDLYVGRFKLAELMFLDVSYNR 203
>AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat
transmembrane neuronal 2 protein protein.
Length = 516
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 13/140 (9%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLK 227
L +L LDLS N++ L PE F + L LHL +N L V + W ++L+
Sbjct: 132 LINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWD-------CRSLE 184
Query: 228 LLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSL 285
LDL++N+L L + L KL L N ++++ A R+S+L + N++ +L
Sbjct: 185 FLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNL 244
Query: 286 PCSLMQC--RLEYIDISSNK 303
C + LE +D++ N+
Sbjct: 245 TCGMEWTWGTLEKLDLTGNE 264
Score = 35.9 bits (79), Expect = 0.26
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 12/164 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 205
R LQ+L+L L + + L LDLS N + L F + L ELHL +NQ
Sbjct: 157 RKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQ 216
Query: 206 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAI-WKLEKLVTLKANDNMISRLPA 264
L + L +L L L NK+ +L + W L L N I +
Sbjct: 217 LTKINFAHFLRL------SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDL 270
Query: 265 TI-GRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNKFD 305
T+ + L+ + +N+L SL ++ L + +S N ++
Sbjct: 271 TVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 314
>AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7
protein.
Length = 1049
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/112 (33%), Positives = 62/112 (55%), Gaps = 10/112 (8%)
Query: 145 GLPRTLQSLYLS--GLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMA-NLSELHL 201
G+P L++L L+ GLK ++++ + LK+L LDLS+N++ +P + +L L L
Sbjct: 672 GMPPNLKNLSLAKNGLKSFSWKK-LQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLIL 730
Query: 202 ANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 253
NNQ +R + ++ L Q L+ LDL+SNK+ + K + L LK
Sbjct: 731 KNNQ--IRSLT--KYFL--QDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLK 776
Score = 40.7 bits (91), Expect = 0.009
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 190 FGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP-KAIWKL 246
F + L EL ++ N L GV D + LK L L N L K + L
Sbjct: 646 FKNLLKLEELDISKNSLSFLPSGVFDG-------MPPNLKNLSLAKNGLKSFSWKKLQCL 698
Query: 247 EKLVTLKANDNMISRLPATIGRIS-TLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNK 303
+ L TL + N ++ +P + S +L+ + +N+++SL +Q +L Y+D+SSNK
Sbjct: 699 KNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNK 758
Query: 304 FDNKQNNS 311
Q S
Sbjct: 759 IQMIQKTS 766
>AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein.
Length = 522
Score = 43.6 bits (98), Expect = 0.001
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 15/144 (10%)
Query: 169 LLKHLAVLDLSNNEIEKLPPEF--GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 226
L + + LDLS N I L E+ A L+ L L +N + + T L
Sbjct: 66 LFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSF------STTPNL 119
Query: 227 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQS 284
K LDL+SNKL + A++ +L+ L L +N IS L P+ G +S L+ +S N L
Sbjct: 120 KCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQ 179
Query: 285 LPCSLMQCR-----LEYIDISSNK 303
P L R L ++D+S N+
Sbjct: 180 FPMDLYVGRFKLAELMFLDVSYNR 203
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/144 (29%), Positives = 67/144 (46%), Gaps = 11/144 (7%)
Query: 172 HLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 230
+L L LSNN I +LPP F ++ L+ L L N L + + GP L+ L
Sbjct: 246 NLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSL----GIFGPM--PNLRELW 299
Query: 231 LTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCS 288
L N + LP ++ L +L L + N IS + P ++ LR ++ +N LQ L +
Sbjct: 300 LYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGN 359
Query: 289 L--MQCRLEYIDISSNKFDNKQNN 310
+ M L+ I + +N+ N
Sbjct: 360 VFRMLANLQNISLQNNRLRQLPGN 383
Score = 39.9 bits (89), Expect = 0.016
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 5/87 (5%)
Query: 220 PQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTIS 278
P +L++L+ +L P + L+ L+ N +SR+ P + +LRY +++
Sbjct: 52 PWNAMSLQILNTHITELNESP--FLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLA 109
Query: 279 SNELQSLPCSLMQ--CRLEYIDISSNK 303
+N+LQ LP L Q LE + +SSN+
Sbjct: 110 NNKLQVLPIGLFQGLDSLESLLLSSNQ 136
>AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein.
Length = 529
Score = 43.6 bits (98), Expect = 0.001
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 13/140 (9%)
Query: 170 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLK 227
L +L LDLS N++ L PE F + L LHL +N L V + W ++L+
Sbjct: 145 LINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWD-------CRSLE 197
Query: 228 LLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSL 285
LDL++N+L L + L KL L N ++++ A R+S+L + N++ +L
Sbjct: 198 FLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNL 257
Query: 286 PCSLMQC--RLEYIDISSNK 303
C + LE +D++ N+
Sbjct: 258 TCGMEWTWGTLEKLDLTGNE 277
Score = 35.9 bits (79), Expect = 0.26
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 12/164 (7%)
Query: 148 RTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 205
R LQ+L+L L + + L LDLS N + L F + L ELHL +NQ
Sbjct: 170 RKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQ 229
Query: 206 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAI-WKLEKLVTLKANDNMISRLPA 264
L + L +L L L NK+ +L + W L L N I +
Sbjct: 230 LTKINFAHFLRL------SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDL 283
Query: 265 TI-GRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNKFD 305
T+ + L+ + +N+L SL ++ L + +S N ++
Sbjct: 284 TVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 327
>BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein.
Length = 421
Score = 43.2 bits (97), Expect = 0.002
Identities = 41/171 (23%), Positives = 85/171 (49%), Gaps = 17/171 (9%)
Query: 140 QFPAKGLPRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEI-EKLPPE--FGRMAN 195
+FP LP++L+ L L ++ + + + L +L +LDL N + + L + F +M
Sbjct: 155 EFPFP-LPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEK 213
Query: 196 LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKA 254
L +L+L +N+L + P + +L L L +N + +P+ + KL KL TL+
Sbjct: 214 LMQLNLCSNRLES---------MPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRM 264
Query: 255 NDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFD 305
+ N + +P I + + ++ N+L+ + LE++ + +N+ +
Sbjct: 265 SHNKLQDIPYNIFNLPNIVELSVGHNKLKQ--AFYIPRNLEHLYLQNNEIE 313
Score = 41.9 bits (94), Expect = 0.004
Identities = 49/182 (26%), Positives = 83/182 (45%), Gaps = 26/182 (14%)
Query: 128 NAPVKLVISDRSQFPAKGLPRTLQSLYLSGLKL-CNFRRDILLLKHLAVLDLSNNEIEKL 186
N P + +R +P +Q LYL ++ + HL ++LS+N+I+
Sbjct: 71 NFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQ 130
Query: 187 PPEFG---RMANLSELHLANNQL-----GVRGVVDWRWLLG-PQITK----------TLK 227
++G ++ NL +LHL +N L + ++ R LLG +I+K L
Sbjct: 131 KIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLE-RLLLGYNEISKLQTNAMDGLVNLT 189
Query: 228 LLDLTSNKLGH---LPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
+LDL N L K K+EKL+ L N + +P G S+L Y ++ +N + S
Sbjct: 190 MLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPP--GLPSSLMYLSLENNSISS 247
Query: 285 LP 286
+P
Sbjct: 248 IP 249
Score = 30.7 bits (66), Expect = 9.8
Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Query: 113 LHLSPLSSLSVTAKNNAPVKL-VISDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDIL-LL 170
LH S L + AK ++L + S+R + GLP +L L L + + L
Sbjct: 198 LHDSLLKD-KIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKL 256
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
L L +S+N+++ +P + N+ EL + +N+L
Sbjct: 257 PKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKL 292
>AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein.
Length = 421
Score = 43.2 bits (97), Expect = 0.002
Identities = 41/171 (23%), Positives = 85/171 (49%), Gaps = 17/171 (9%)
Query: 140 QFPAKGLPRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEI-EKLPPE--FGRMAN 195
+FP LP++L+ L L ++ + + + L +L +LDL N + + L + F +M
Sbjct: 155 EFPFP-LPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEK 213
Query: 196 LSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKA 254
L +L+L +N+L + P + +L L L +N + +P+ + KL KL TL+
Sbjct: 214 LMQLNLCSNRLES---------MPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRM 264
Query: 255 NDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFD 305
+ N + +P I + + ++ N+L+ + LE++ + +N+ +
Sbjct: 265 SHNKLQDIPYNIFNLPNIVELSVGHNKLKQ--AFYIPRNLEHLYLQNNEIE 313
Score = 41.9 bits (94), Expect = 0.004
Identities = 49/182 (26%), Positives = 83/182 (45%), Gaps = 26/182 (14%)
Query: 128 NAPVKLVISDRSQFPAKGLPRTLQSLYLSGLKL-CNFRRDILLLKHLAVLDLSNNEIEKL 186
N P + +R +P +Q LYL ++ + HL ++LS+N+I+
Sbjct: 71 NFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQ 130
Query: 187 PPEFG---RMANLSELHLANNQL-----GVRGVVDWRWLLG-PQITK----------TLK 227
++G ++ NL +LHL +N L + ++ R LLG +I+K L
Sbjct: 131 KIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLE-RLLLGYNEISKLQTNAMDGLVNLT 189
Query: 228 LLDLTSNKLGH---LPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 284
+LDL N L K K+EKL+ L N + +P G S+L Y ++ +N + S
Sbjct: 190 MLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPP--GLPSSLMYLSLENNSISS 247
Query: 285 LP 286
+P
Sbjct: 248 IP 249
Score = 30.7 bits (66), Expect = 9.8
Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Query: 113 LHLSPLSSLSVTAKNNAPVKL-VISDRSQFPAKGLPRTLQSLYLSGLKLCNFRRDIL-LL 170
LH S L + AK ++L + S+R + GLP +L L L + + L
Sbjct: 198 LHDSLLKD-KIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKL 256
Query: 171 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 206
L L +S+N+++ +P + N+ EL + +N+L
Sbjct: 257 PKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKL 292
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.136 0.405
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 58,725,032
Number of Sequences: 224733
Number of extensions: 2422713
Number of successful extensions: 8021
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 243
Number of HSP's successfully gapped in prelim test: 275
Number of HSP's that attempted gapping in prelim test: 5262
Number of HSP's gapped (non-prelim): 1704
length of query: 410
length of database: 73,234,838
effective HSP length: 92
effective length of query: 318
effective length of database: 52,559,402
effective search space: 16713889836
effective search space used: 16713889836
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 66 (30.7 bits)
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