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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001435-TA|BGIBMGA001435-PA|IPR000884|Thrombospondin,
type I, IPR010294|ADAM-TS Spacer 1
         (476 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and ...   392   e-108
BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase w...   365   e-100
AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein.   364   e-100
AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.   303   8e-82
AF140675-1|AAD56358.1|  997|Homo sapiens zinc metalloprotease AD...   303   8e-82
BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase w...   289   1e-77
AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.    288   3e-77
AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease disinte...   281   3e-75
AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.    281   3e-75
AB209515-1|BAD92752.1|  847|Homo sapiens a disintegrin-like and ...   279   2e-74
AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptida...   274   3e-73
BC036515-1|AAH36515.1|  967|Homo sapiens ADAM metallopeptidase w...   264   6e-70
AP001697-1|BAA95502.1|  967|Homo sapiens metalloprotease with th...   263   1e-69
AL162080-1|CAB82413.1|  550|Homo sapiens hypothetical protein pr...   263   1e-69
AF207664-1|AAF23772.1|  967|Homo sapiens matrix metalloprotease ...   263   1e-69
AF170084-1|AAF15317.1|  967|Homo sapiens metalloproteinase with ...   263   1e-69
AF060152-1|AAD48080.1|  950|Homo sapiens METH1 protein protein.       263   1e-69
AB037767-1|BAA92584.1|  999|Homo sapiens KIAA1346 protein protein.    263   1e-69
AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein.   262   2e-69
AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.           259   1e-68
AF140674-1|AAD56357.1|  860|Homo sapiens zinc metalloprotease AD...   258   2e-68
BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.     256   9e-68
BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase w...   256   9e-68
AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and ...   255   2e-67
AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disinte...   252   2e-66
AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.            252   2e-66
DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase w...   252   3e-66
AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-protein...   252   3e-66
BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase w...   249   2e-65
AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and ...   249   2e-65
AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin metalloprot...   249   2e-65
AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.    249   2e-65
AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein.   248   2e-65
AL358817-5|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase w...   242   2e-63
AL358817-4|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase w...   242   2e-63
AL355344-5|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase w...   242   2e-63
AL355344-4|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase w...   242   2e-63
AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.            241   4e-63
AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and ...   241   4e-63
AK131344-1|BAD18500.1|  502|Homo sapiens protein ( Homo sapiens ...   239   2e-62
BC089435-1|AAH89435.1|  918|Homo sapiens ADAMTS8 protein protein.     236   1e-61
AF060153-1|AAD48081.1|  890|Homo sapiens METH2 protein protein.       236   1e-61
AJ345098-1|CAC87943.1| 1223|Homo sapiens metalloprotease-disinte...   234   6e-61
BC113874-1|AAI13875.1|  676|Homo sapiens ADAMTS8 protein protein.     231   4e-60
AB209717-1|BAD92954.1|  418|Homo sapiens ADAMTS-8 precursor vari...   229   2e-59
AP001697-2|BAA95503.1|  517|Homo sapiens disintegrin-like and me...   214   7e-55
BC093777-1|AAH93777.1|  930|Homo sapiens ADAM metallopeptidase w...   213   1e-54
BC093775-1|AAH93775.1|  930|Homo sapiens ADAM metallopeptidase w...   213   1e-54
AF142099-1|AAD49577.1|  930|Homo sapiens aggrecanase-2 protein.       213   1e-54
AF141293-1|AAF02493.1|  518|Homo sapiens ADAMTS5 protein protein.     211   5e-54
AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein pr...   208   2e-53
AK128469-1|BAC87455.1|  327|Homo sapiens protein ( Homo sapiens ...   208   4e-53
BC030262-1|AAH30262.1|  439|Homo sapiens ADAMTS-like 1 protein.       206   1e-52
AY358886-1|AAQ89245.1|  837|Homo sapiens ADAMTS4 protein.             203   9e-52
AF148213-1|AAD41494.1|  837|Homo sapiens aggrecanase-1 protein.       203   9e-52
AB014588-1|BAA31663.2|  849|Homo sapiens KIAA0688 protein protein.    203   9e-52
AL590714-6|CAH72146.1|  837|Homo sapiens ADAM metallopeptidase w...   202   3e-51
BC109114-1|AAI09115.1|  950|Homo sapiens ADAM metallopeptidase w...   201   5e-51
AJ315733-1|CAC86014.1|  950|Homo sapiens metalloprotease disinte...   201   5e-51
AB209685-1|BAD92922.1|  530|Homo sapiens a disintegrin and metal...   200   9e-51
BC063293-1|AAH63293.1|  837|Homo sapiens ADAM metallopeptidase w...   198   3e-50
AY044847-1|AAL02262.1|  837|Homo sapiens aggrecanase 1 protein.       198   3e-50
DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase w...   197   6e-50
AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand factor-c...   197   6e-50
AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase ...   197   6e-50
AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase ...   197   6e-50
AL158826-24|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase ...   197   6e-50
AL158826-22|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase ...   197   6e-50
AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, vari...   197   6e-50
AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.            197   6e-50
AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand factor-c...   197   6e-50
AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase w...   197   8e-50
AL158826-23|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase ...   197   8e-50
AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.   197   8e-50
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein.    195   2e-49
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein.       195   2e-49
AL353895-1|CAI14851.1|  525|Homo sapiens ADAMTS-like 1 protein.       195   3e-49
AF237652-1|AAK15041.1|  766|Homo sapiens a disintegrin-like and ...   195   3e-49
AF176313-1|AAK84170.1|  525|Homo sapiens ADAM-TS related protein...   194   4e-49
AY358327-1|AAQ88693.1|  525|Homo sapiens ADAMTSL1 protein.            194   6e-49
AY358118-1|AAQ88485.1| 1097|Homo sapiens ADAMTS13 protein.            187   9e-47
BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.    185   3e-46
AK092324-1|BAC03862.1|  296|Homo sapiens protein ( Homo sapiens ...   167   7e-41
BX649571-2|CAI18773.1|  951|Homo sapiens ADAMTS-like 2 protein.       166   1e-40
BX649571-1|CAM26559.1| 1060|Homo sapiens ADAMTS-like 2 protein.       166   1e-40
BX629352-2|CAI23592.1|  951|Homo sapiens ADAMTS-like 2 protein.       166   1e-40
BX629352-1|CAM28356.1| 1060|Homo sapiens ADAMTS-like 2 protein.       166   1e-40
BX324209-2|CAI17317.1|  951|Homo sapiens ADAMTS-like 2 protein.       166   1e-40
BX324209-1|CAM24586.1| 1060|Homo sapiens ADAMTS-like 2 protein.       166   1e-40
BC050544-1|AAH50544.1|  951|Homo sapiens ADAMTS-like 2 protein.       166   1e-40
AB011177-1|BAA25531.2| 1031|Homo sapiens KIAA0605 protein protein.    162   3e-39
BC040620-1|AAH40620.1|  356|Homo sapiens ADAMTSL5 protein protein.    153   2e-36
AK131571-1|BAD18703.1|  471|Homo sapiens protein ( Homo sapiens ...   152   2e-36
AJ011374-1|CAB66157.1|  364|Homo sapiens hypothetical protein pr...   147   6e-35
AK131551-1|BAD18685.1|  577|Homo sapiens protein ( Homo sapiens ...   139   2e-32
BX641106-1|CAE46049.1|  321|Homo sapiens hypothetical protein pr...   135   4e-31
AK131414-1|BAD18561.1|  493|Homo sapiens protein ( Homo sapiens ...   128   6e-29
AK131403-1|BAD18550.1|  415|Homo sapiens protein ( Homo sapiens ...   121   5e-27
AY358122-1|AAQ88489.1|  877|Homo sapiens ENWT2803 protein.            120   1e-26
AL356356-13|CAI15500.2| 1074|Homo sapiens ADAMTS-like 4 protein.      120   1e-26
AL356356-12|CAI15499.1|  877|Homo sapiens ADAMTS-like 4 protein.      120   1e-26
BC042057-1|AAH42057.1|  129|Homo sapiens PAPLN protein protein.        96   3e-19
X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA...    88   6e-17
X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for ...    88   6e-17
AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precur...    88   6e-17
L12350-1|AAA03703.1| 1172|Homo sapiens thrombospondin 2 protein.       83   2e-15
BX322234-1|CAI23645.1| 1172|Homo sapiens thrombospondin 2 protein.     83   2e-15
X70872-1|CAA50220.1|  469|Homo sapiens properdin protein.              81   6e-15
X57748-1|CAA40914.1|  469|Homo sapiens properdin protein.              81   6e-15
M83652-1|AAA36489.1|  469|Homo sapiens complement omponent prope...    81   6e-15
BC015756-1|AAH15756.1|  469|Homo sapiens complement factor prope...    81   6e-15
AY297813-1|AAP43692.1|  469|Homo sapiens properdin P factor, com...    81   6e-15
AL009172-3|CAA15658.1|  454|Homo sapiens complement factor prope...    81   6e-15
AF005668-1|AAB62886.1|  469|Homo sapiens properdin protein.            81   6e-15
AF005666-1|AAC51626.1|  469|Homo sapiens properdin protein.            81   6e-15
AF005665-1|AAB63280.1|  469|Homo sapiens properdin protein.            81   6e-15
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq...    79   3e-14
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq...    79   3e-14
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq...    79   3e-14
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq...    79   3e-14
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq...    79   3e-14
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq...    79   3e-14
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq...    79   3e-14
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq...    79   3e-14
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.            79   3e-14
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.           79   3e-14
BC077726-1|AAH77726.1| 1151|Homo sapiens sema domain, seven thro...    79   4e-14
AB040878-1|BAA95969.1| 1202|Homo sapiens KIAA1445 protein protein.     79   4e-14
U52840-1|AAC09473.1| 1074|Homo sapiens semaphorin F homolog prot...    78   8e-14
BC115696-1|AAI15697.1| 1074|Homo sapiens sema domain, seven thro...    77   1e-13
AY358124-1|AAQ88491.1| 1092|Homo sapiens SEMA5B protein.               77   1e-13
AK027344-1|BAB55049.1|  741|Homo sapiens protein ( Homo sapiens ...    77   1e-13
AY358351-1|AAQ88717.1|  945|Homo sapiens GARS1883 protein.             67   1e-10
AY126437-1|AAM95701.1|  934|Homo sapiens transmembrane receptor ...    67   1e-10
AL359832-2|CAI16738.1|  934|Homo sapiens unc-5 homolog B (C. ele...    67   1e-10
AL359832-1|CAI16737.1|  945|Homo sapiens unc-5 homolog B (C. ele...    67   1e-10
AL359384-3|CAI16090.1|  934|Homo sapiens unc-5 homolog B (C. ele...    67   1e-10
AL359384-2|CAI16089.1|  945|Homo sapiens unc-5 homolog B (C. ele...    67   1e-10
AB096256-1|BAC57998.1|  945|Homo sapiens p53-regulated receptor ...    67   1e-10
BC041156-1|AAH41156.1|  597|Homo sapiens UNC5C protein protein.        66   2e-10
AF055634-1|AAC67491.1|  931|Homo sapiens transmembrane receptor ...    66   2e-10
AC098584-1|AAY41022.1|  506|Homo sapiens unknown protein.              66   2e-10
AY358147-1|AAQ88514.1|  953|Homo sapiens UNC5D protein.                66   3e-10
AB055056-1|BAB83663.1|  948|Homo sapiens KIAA1777 protein (Unc5h...    66   3e-10
AK023228-1|BAB14479.1|  622|Homo sapiens protein ( Homo sapiens ...    64   8e-10
AB005297-1|BAA23647.1| 1584|Homo sapiens BAI 1 protein.                61   7e-09
BC111720-1|AAI11721.1| 1522|Homo sapiens brain-specific angiogen...    59   3e-08
AL391807-1|CAI21673.1| 1522|Homo sapiens brain-specific angiogen...    59   3e-08
AL359714-1|CAH71522.1| 1522|Homo sapiens brain-specific angiogen...    59   3e-08
AL356117-1|CAH71772.1| 1522|Homo sapiens brain-specific angiogen...    59   3e-08
AL160401-1|CAH73864.1| 1522|Homo sapiens brain-specific angiogen...    59   3e-08
AL158051-1|CAI19625.1| 1522|Homo sapiens brain-specific angiogen...    59   3e-08
AL133378-1|CAC34969.2| 1522|Homo sapiens brain-specific angiogen...    59   3e-08
AK023772-1|BAB14673.1|  538|Homo sapiens protein ( Homo sapiens ...    59   3e-08
AB011122-1|BAA25476.2| 1524|Homo sapiens KIAA0550 protein protein.     59   3e-08
AB005299-1|BAA25363.1| 1522|Homo sapiens BAI 3 protein.                59   3e-08
AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein.     58   5e-08
X86328-1|CAA60121.1|  820|Homo sapiens complement C7 protein.          57   2e-07
J03507-1|AAA51861.1|  843|Homo sapiens C7 protein.                     57   2e-07
BC094811-1|AAH94811.1|  602|Homo sapiens ADAMTSL4 protein protein.     57   2e-07
BC071852-1|AAH71852.1|  602|Homo sapiens ADAMTSL4 protein protein.     57   2e-07
BC063851-1|AAH63851.1|  843|Homo sapiens complement component 7 ...    57   2e-07
AK131380-1|BAD18531.1|  301|Homo sapiens protein ( Homo sapiens ...    57   2e-07
AY358143-1|AAQ88510.1|  219|Homo sapiens FVSY9334 protein.             56   2e-07
X72177-1|CAA50994.1|  934|Homo sapiens complement component C6 p...    56   3e-07
J05064-1|AAA51860.1|  934|Homo sapiens C6 protein.                     56   3e-07
J05024-1|AAA59668.1|  934|Homo sapiens completement component C6...    56   3e-07
BC035723-1|AAH35723.1|  934|Homo sapiens C6 protein protein.           56   3e-07
AB126592-1|BAD02321.1|  934|Homo sapiens complement component 6 ...    56   3e-07
BC033727-1|AAH33727.1|  364|Homo sapiens Unknown (protein for IM...    55   5e-07
AL354919-5|CAI16890.1| 1584|Homo sapiens brain-specific angiogen...    55   6e-07
AL354919-2|CAM12875.1| 1554|Homo sapiens brain-specific angiogen...    55   6e-07
AB065648-1|BAC05874.1| 1573|Homo sapiens seven transmembrane hel...    55   6e-07
AB005298-1|BAA25362.1| 1572|Homo sapiens BAI 2 protein.                55   6e-07
U08006-1|AAA82124.1|  584|Homo sapiens complement 8 alpha subuni...    54   1e-06
M16974-1|AAA52200.1|  584|Homo sapiens C8A protein.                    53   2e-06
BC132913-1|AAI32914.1|  584|Homo sapiens complement component 8,...    53   2e-06
BC132911-1|AAI32912.1|  584|Homo sapiens complement component 8,...    53   2e-06
AL121998-2|CAI19172.1|  584|Homo sapiens complement component 8,...    53   2e-06
DQ266047-1|ABB70405.1|  570|Homo sapiens ADAMTS16s alternative s...    53   3e-06
X04393-1|CAA27981.1|  545|Homo sapiens complement C8-beta propet...    52   3e-06
M16973-1|AAA51862.1|  591|Homo sapiens C8B protein.                    52   3e-06
BC130575-1|AAI30576.1|  591|Homo sapiens complement component 8,...    52   3e-06
AL121998-1|CAC18532.1|  591|Homo sapiens complement component 8,...    52   3e-06
AL354919-7|CAM12879.1| 1500|Homo sapiens brain-specific angiogen...    52   4e-06
AL354919-3|CAM12876.1| 1499|Homo sapiens brain-specific angiogen...    52   4e-06
AY172951-1|AAO45695.1|  387|Homo sapiens disintegrin and metallo...    52   6e-06
AK122677-1|BAC85503.1|  375|Homo sapiens protein ( Homo sapiens ...    51   8e-06
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi...    51   1e-05
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi...    51   1e-05
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi...    51   1e-05
AL359934-1|CAB95770.1|  432|Homo sapiens ADAMTS7, alternatively ...    50   1e-05
U12471-1|AAA21127.1|   59|Homo sapiens thrombospondin-1p180 prot...    50   2e-05
DQ364570-1|ABC88384.1|  127|Homo sapiens ADAM metallopeptidase w...    50   2e-05
BC027478-1|AAH27478.1|  424|Homo sapiens ADAMTSL4 protein protein.     49   4e-05
AF217974-1|AAG17217.1|  237|Homo sapiens unknown protein.              48   5e-05
AL359513-1|CAH71657.1|  852|Homo sapiens thrombospondin, type I,...    48   1e-04
AL354919-4|CAM12877.1|  847|Homo sapiens brain-specific angiogen...    48   1e-04
AL354919-1|CAM12874.1| 1466|Homo sapiens brain-specific angiogen...    48   1e-04
AB044385-1|BAA96553.1|  852|Homo sapiens transmembrane molecule ...    48   1e-04
BC028145-1|AAH28145.1|  401|Homo sapiens Unknown (protein for IM...    47   1e-04
AL353895-4|CAI14853.2|  470|Homo sapiens ADAMTS-like 1 protein.        47   1e-04
AF251058-1|AAK34948.1|  417|Homo sapiens thrombospondin protein.       47   1e-04
AY692423-1|AAW47396.1|  270|Homo sapiens ADAMTS6 variant 2 protein.    46   2e-04
AK131039-1|BAC85480.1|  288|Homo sapiens protein ( Homo sapiens ...    46   2e-04
AK129873-1|BAC85245.1|  226|Homo sapiens protein ( Homo sapiens ...    46   2e-04
BC016451-1|AAH16451.1|  364|Homo sapiens ADAMTS3 protein protein.      46   4e-04
AB023177-1|BAA76804.2| 1502|Homo sapiens KIAA0960 protein protein.     46   4e-04
BC041974-1|AAH41974.1|  257|Homo sapiens SPON1 protein protein.        45   5e-04
BC019825-1|AAH19825.1|  259|Homo sapiens SPON1 protein protein.        45   5e-04
AK074803-1|BAC11217.1|  807|Homo sapiens protein ( Homo sapiens ...    45   5e-04
AB051390-1|BAB18461.1|  807|Homo sapiens VSGP/F-spondin protein.       45   5e-04
AB018305-1|BAA34482.2|  724|Homo sapiens KIAA0762 protein protein.     45   5e-04
AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein.     45   7e-04
M25631-1|AAA36741.1|  397|Homo sapiens thrombospondin protein.         44   9e-04
AY358149-1|AAQ88516.1|  429|Homo sapiens THSD1 protein.                44   9e-04
AF542080-1|AAN17826.1| 1156|Homo sapiens cartilage intermediate ...    44   0.002
BC100790-1|AAI00791.1|  284|Homo sapiens C9orf94 protein protein.      42   0.005
BC100788-1|AAI00789.1|  467|Homo sapiens C9orf94 protein protein.      42   0.005
AB051466-1|BAB21770.1| 1536|Homo sapiens KIAA1679 protein protein.     42   0.005
J04506-1|AAB59433.1|  491|Homo sapiens complement component C6 p...    41   0.008
BC035776-1|AAH35776.1| 1184|Homo sapiens cartilage intermediate ...    41   0.008
AY358904-1|AAQ89263.1| 1184|Homo sapiens CILP protein.                 41   0.008
AF035455-1|AAF14689.1| 1184|Homo sapiens cartilage intermediate ...    41   0.008
AF035408-1|AAC33838.1| 1184|Homo sapiens cartilage intermediate ...    41   0.008
AB022430-1|BAA76692.1| 1184|Homo sapiens cartilage intermediate ...    41   0.008
AL133463-1|CAC16127.3|  418|Homo sapiens chromosome 20 open read...    40   0.014
AL050320-3|CAC36074.2|  418|Homo sapiens chromosome 20 open read...    40   0.014
AF005664-1|AAB63279.1|  160|Homo sapiens properdin protein.            40   0.019
BC033125-1|AAH33125.1|  740|Homo sapiens THSD7B protein protein.       39   0.033
BC019344-1|AAH19344.1|  740|Homo sapiens THSD7B protein protein.       39   0.033
AK128724-1|BAC87592.1|  160|Homo sapiens protein ( Homo sapiens ...    38   0.10 
Z98053-1|CAB10848.1|  381|Homo sapiens hCYR61 protein protein.         36   0.41 
Y12084-1|CAA72802.1|  381|Homo sapiens Gig1 protein protein.           36   0.41 
Y11307-1|CAA72167.1|  381|Homo sapiens CYR61 protein protein.          36   0.41 
U62015-1|AAB58319.1|  381|Homo sapiens Cyr61 protein.                  36   0.41 
CR536519-1|CAG38757.1|  381|Homo sapiens CYR61 protein.                36   0.41 
BC016952-1|AAH16952.1|  381|Homo sapiens cysteine-rich, angiogen...    36   0.41 
BC009199-1|AAH09199.1|  381|Homo sapiens cysteine-rich, angiogen...    36   0.41 
BC001271-1|AAH01271.1|  381|Homo sapiens cysteine-rich, angiogen...    36   0.41 
AY443495-1|AAR05446.1|  381|Homo sapiens cysteine-rich, angiogen...    36   0.41 
AK223385-1|BAD97105.1|  381|Homo sapiens cysteine-rich, angiogen...    36   0.41 
AF307860-1|AAG59863.1|  381|Homo sapiens CYR61 protein protein.        36   0.41 
AF031385-1|AAB84227.1|  381|Homo sapiens Cyr61 protein protein.        36   0.41 
AF003594-1|AAB61240.1|  381|Homo sapiens growth-factor inducible...    36   0.41 
AF003114-1|AAF21597.1|  334|Homo sapiens CYR61 protein.                36   0.41 
Z99289-6|CAI42331.1|  354|Homo sapiens WNT1 inducible signaling ...    34   0.95 
Z99289-1|CAB16556.1|  331|Homo sapiens WNT1 inducible signaling ...    34   0.95 
BC105941-1|AAI05942.1|  372|Homo sapiens WNT1 inducible signalin...    34   0.95 
AY358350-1|AAQ88716.1|  354|Homo sapiens WISP-3 protein.               34   0.95 
AY358349-1|AAQ88715.1|  372|Homo sapiens WISP-3 protein.               34   0.95 
AL512299-1|CAI19998.1|  354|Homo sapiens WNT1 inducible signalin...    34   0.95 
AF143679-1|AAD31517.1|  331|Homo sapiens lost in inflammatory br...    34   0.95 
AF100781-1|AAC96323.1|  354|Homo sapiens connective tissue growt...    34   0.95 
X78947-1|CAA55544.1|  349|Homo sapiens connective tissue growth ...    34   1.3  
U14750-1|AAA75378.1|  275|Homo sapiens connective tissue growth ...    34   1.3  
M92934-1|AAA91279.1|  349|Homo sapiens connective tissue growth ...    34   1.3  
DQ097843-1|AAZ29611.1|  349|Homo sapiens connective tissue growt...    34   1.3  
CR541759-1|CAG46559.1|  349|Homo sapiens CTGF protein.                 34   1.3  
CR541734-1|CAG46534.1|  349|Homo sapiens CTGF protein.                 34   1.3  
BT019795-1|AAV38598.1|  349|Homo sapiens connective tissue growt...    34   1.3  
BT019794-1|AAV38597.1|  349|Homo sapiens connective tissue growt...    34   1.3  
BC087839-1|AAH87839.1|  349|Homo sapiens connective tissue growt...    34   1.3  
AY550024-1|AAS55639.1|  349|Homo sapiens connective tissue growt...    34   1.3  
AY395801-1|AAQ95223.1|  349|Homo sapiens connective tissue growt...    34   1.3  
AL354866-1|CAC44023.1|  349|Homo sapiens connective tissue growt...    34   1.3  
BC074841-1|AAH74841.1|  367|Homo sapiens WNT1 inducible signalin...    33   1.7  
BC074840-1|AAH74840.1|  367|Homo sapiens WNT1 inducible signalin...    33   1.7  
AY196487-1|AAP43925.1|  195|Homo sapiens WISP1tc protein.              33   1.7  
AF100779-1|AAC96321.1|  367|Homo sapiens connective tissue growt...    33   1.7  
AB034725-1|BAB17849.1|  280|Homo sapiens WISP-1 variant protein.       33   1.7  
BC132765-1|AAI32766.1|  832|Homo sapiens ADAM metallopeptidase d...    33   2.2  
BC132763-1|AAI32764.1|  832|Homo sapiens ADAM metallopeptidase d...    33   2.2  
BC121046-1|AAI21047.1|  153|Homo sapiens ADAM18 protein protein.       33   2.2  
BC121045-1|AAI21046.1|  739|Homo sapiens ADAM metallopeptidase d...    33   2.2  
AY358321-1|AAQ88687.1|  715|Homo sapiens ADAM18 protein.               33   2.2  
AJ133004-1|CAB40812.1|  739|Homo sapiens tMDC III protein protein.     33   2.2  
AJ005580-1|CAC20565.1|  832|Homo sapiens Adam23 protein protein.       33   2.2  
AC010731-1|AAY14948.1|  179|Homo sapiens unknown protein.              33   2.2  
AB009672-1|BAA32351.1|  832|Homo sapiens MDC3 protein.                 33   2.2  
AL122085-1|CAB59258.1|  111|Homo sapiens hypothetical protein pr...    33   2.9  
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein.       32   5.1  
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein.                 32   5.1  
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein.           32   5.1  
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein.               32   5.1  
AL050325-2|CAB65783.4|  234|Homo sapiens R-spondin family, membe...    31   6.7  
BC064379-1|AAH64379.1|  250|Homo sapiens WNT1 inducible signalin...    31   8.9  
BC017782-1|AAH17782.1|  250|Homo sapiens WNT1 inducible signalin...    31   8.9  
AY358915-1|AAQ89274.1|  250|Homo sapiens WISP-2 protein.               31   8.9  
AL139352-2|CAB94788.1|  250|Homo sapiens WNT1 inducible signalin...    31   8.9  
AF100780-1|AAC96322.1|  250|Homo sapiens connective tissue growt...    31   8.9  
AF083500-1|AAC70350.1|  250|Homo sapiens connective tissue growt...    31   8.9  
AF074604-1|AAC26794.1|  250|Homo sapiens connective tissue growt...    31   8.9  

>AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and
           metalloprotease (reprolysin type) with thrombospondin ty
           protein.
          Length = 1593

 Score =  392 bits (965), Expect = e-108
 Identities = 184/478 (38%), Positives = 272/478 (56%), Gaps = 19/478 (3%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQT 60
           ++D   QC LQ+G  A  C ++  +C+ LWC V   C + +  AA GT CG   WC    
Sbjct: 471 IYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTQCGEKKWCMAGK 530

Query: 61  CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           C+     P    GGWG WS WS CSRTCGAGV +  R CNNPEP   G YC G+R RY++
Sbjct: 531 CITVGKKPESIPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRL 590

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEMLG 180
           CN  PC    P+FR++QCS  + +PYKNE +  W P F+   PCEL C P DG   E + 
Sbjct: 591 CNVHPCRSEAPTFRQMQCSEFDTVPYKNE-LYHWFPIFNPAHPCELYCRPIDGQFSEKML 649

Query: 181 GFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYT 240
             V DGTPC +   SR++CI+G+C  VGCD+ +DS+  ED CGVC GDG++C+TV+ ++ 
Sbjct: 650 DAVIDGTPCFEGGNSRNVCINGICKMVGCDYEIDSNATEDRCGVCLGDGSSCQTVRKMFK 709

Query: 241 KGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLT-EYFV 299
           +     SG+ ++ +IP G+R++++ E    GN+++I S    + +LNG         Y +
Sbjct: 710 Q--KEGSGYVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKL 767

Query: 300 AGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL----HKK 355
           AG    Y+R  D EK+  +GP  E + + Q +F  +  NPG+ Y+YT+ K  L     + 
Sbjct: 768 AGTVFQYDRKGDLEKLMATGPTNESVWI-QLLF--QVTNPGIKYEYTIQKDGLDNDVEQM 824

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC- 414
           + ++   WT CSVTCG G  R+   CI + + +V+ + C     P  +   K+C + AC 
Sbjct: 825 YFWQYGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGR--QKKCHEKACP 882

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMN--KVVDDSECGQVIKPITTIKC 470
             WW G W  CS  C   GE   K+R+V C+  +++  + +  ++C  ++KP T + C
Sbjct: 883 PRWWAGEWEACSATCGPHGE---KKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSC 937



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 35/124 (28%), Positives = 51/124 (41%), Gaps = 14/124 (11%)

Query: 353  HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKP 412
            H    + +  W+ CS TCG+G   +  EC  Q       S C  I+ P      K+C   
Sbjct: 1311 HGSAHWIVGNWSECSTTCGLGAYWKRVECTTQMD-----SDCAAIQRPDPA---KRCHLR 1362

Query: 413  ACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQV--IKPITTIKC 470
             C  W VG W+ CS+ C        K R + CVD   ++ +    C  +  I P  ++ C
Sbjct: 1363 PCAGWKVGNWSKCSRNC----SGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSC 1418

Query: 471  ADVP 474
               P
Sbjct: 1419 NPEP 1422



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 10/90 (11%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQ-RVVEQSQCYHIE--PPRHQALMKQCRKPAC 414
            +++  W+ CS  C  G+  R  +C+D    R +    C  +   PP    L   C    C
Sbjct: 1367 WKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPP---PLSMSCNPEPC 1423

Query: 415  VHWWVGAWNPCSKLCHMPGEEVTKERSVYC 444
              W V  W+ CS+ C   G  V +ER V+C
Sbjct: 1424 EAWQVEPWSQCSRSC---GGGV-QERGVFC 1449



 Score = 40.3 bits (90), Expect = 0.014
 Identities = 29/102 (28%), Positives = 39/102 (38%), Gaps = 15/102 (14%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
            ++++  W+ CS +CG G   R   C            C   + P        C +  C H
Sbjct: 1425 AWQVEPWSQCSRSCGGGVQERGVFC--------PGGLCDWTKRPTSTM---SCNEHLCCH 1473

Query: 417  WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            W  G W+ CS  C   G    K R V CV    NK  D  +C
Sbjct: 1474 WATGNWDLCSTSC---GGGFQK-RIVQCVPSEGNKTEDQDQC 1511



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 7/73 (9%)

Query: 362 EWTPCSVTCGV-GYTRRYYECID---QHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH- 416
           EW  CS TCG  G  +R   CI      ++ +  + C H+  P+   L+   R   C   
Sbjct: 889 EWEACSATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPK--TLLSCNRDILCPSD 946

Query: 417 WWVGAWNPCSKLC 429
           W VG W+ CS  C
Sbjct: 947 WTVGNWSECSVSC 959



 Score = 39.1 bits (87), Expect = 0.033
 Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 2/53 (3%)

Query: 363  WTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
            W  CS +CG G+ +R  +C+  +  +  +Q QC     PR     K+C + AC
Sbjct: 1479 WDLCSTSCGGGFQKRIVQCVPSEGNKTEDQDQCLCDHKPRPPE-FKKCNQQAC 1530



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 14/26 (53%), Positives = 17/26 (65%), Gaps = 2/26 (7%)

Query: 81  WSECSRTCGAGVSTQSREC--NNPEP 104
           WSECS +CG GV  +S  C  N+ EP
Sbjct: 952 WSECSVSCGGGVRIRSVTCAKNHDEP 977


>BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 7 protein.
          Length = 1686

 Score =  365 bits (897), Expect = e-100
 Identities = 177/481 (36%), Positives = 251/481 (52%), Gaps = 22/481 (4%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQT 60
           ++D + QC LQ+GA +  C  +  +C  LWC V   C + +  A  GT CG + WC +  
Sbjct: 467 LYDVSHQCRLQYGAYSAFCEDMDNVCHTLWCSVGTTCHSKLDAAVDGTRCGENKWCLSGE 526

Query: 61  CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           CV     P   DGGW  WS WS CSR+CG GV +  R+C  P P   G YC+G+R R+++
Sbjct: 527 CVPVGFRPEAVDGGWSGWSAWSICSRSCGMGVQSAERQCTQPTPKYKGRYCVGERKRFRL 586

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEMLG 180
           CN   CP   PSFR VQCS  + M YK + +  WVP  +   PCEL C P +    E L 
Sbjct: 587 CNLQACPAGRPSFRHVQCSHFDAMLYKGQ-LHTWVPVVNDVNPCELHCRPANEYFAEKLR 645

Query: 181 GFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYT 240
             V DGTPC Q   SRD+CI+G+C  VGCD+ +DS   ED CGVC G+G+ C TV G + 
Sbjct: 646 DAVVDGTPCYQVRASRDLCINGICKNVGCDFEIDSGAMEDRCGVCHGNGSTCHTVSGTFE 705

Query: 241 KGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLT-EYFV 299
           +      G+ +V +IPAG+R ++IQE     N++++ S    + FLNG        +Y V
Sbjct: 706 E--AEGLGYVDVGLIPAGAREIRIQEVAEAANFLALRSEDPEKYFLNGGWTIQWNGDYQV 763

Query: 300 AGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQR-LHKK--- 355
           AG    Y R  +WE +   GP  E + + Q +F  +  NPGV Y+YT+ ++   H +   
Sbjct: 764 AGTTFTYARRGNWENLTSPGPTKEPVWI-QLLF--QESNPGVHYEYTIHREAGGHDEVPP 820

Query: 356 --HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
              S+    WT C+VTCG G  R+   C+++    V++  C  +  P  Q   ++C +  
Sbjct: 821 PVFSWHYGPWTKCTVTCGRGVQRQNVYCLERQAGPVDEEHCDPLGRPDDQ--QRKCSEQP 878

Query: 414 C-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKV---MNKVVDDSECGQVIKPITTIK 469
           C   WW G W  CS  C   G      R+V C+  V       ++   C  + +P T   
Sbjct: 879 CPARWWAGEWQLCSSSC---GPGGLSRRAVLCIRSVGLDEQSALEPPACEHLPRPPTETP 935

Query: 470 C 470
           C
Sbjct: 936 C 936



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 15/119 (12%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEP-PRHQALMKQCRKPACV 415
            ++    W+ CS +CG G + R  +C+D   R +   + +H +P P      + C    C+
Sbjct: 1465 TWHSGNWSKCSRSCGGGSSVRDVQCVDT--RDLRPLRPFHCQPGPAKPPAHRPCGAQPCL 1522

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
             W+  +W  CS+ C   GE+   +R V C +  +        C + ++P TT  C   P
Sbjct: 1523 SWYTSSWRECSEACG-GGEQ---QRLVTCPEPGL--------CEEALRPNTTRPCNTHP 1569



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 36/121 (29%), Positives = 51/121 (42%), Gaps = 19/121 (15%)

Query: 362 EWTPCSVTCGVG-YTRRYYECIDQ----HQRVVEQSQCYHI-EPPRHQALMKQCRKPACV 415
           EW  CS +CG G  +RR   CI       Q  +E   C H+  PP      +    PA  
Sbjct: 887 EWQLCSSSCGPGGLSRRAVLCIRSVGLDEQSALEPPACEHLPRPPTETPCNRHVPCPAT- 945

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPA 475
            W VG W+ CS  C     E T+ R+V C +           C +  +P + + C+ +P 
Sbjct: 946 -WAVGNWSQCSVTC----GEGTQRRNVLCTNDT------GVPCDEAQQPASEVTCS-LPL 993

Query: 476 C 476
           C
Sbjct: 994 C 994



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 15/115 (13%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
            S+  S W  CS  CG G  +R   C        E   C     P      + C    C  
Sbjct: 1523 SWYTSSWRECSEACGGGEQQRLVTC-------PEPGLCEEALRPN---TTRPCNTHPCTQ 1572

Query: 417  WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS-ECGQVIKPITTIKC 470
            W VG W  CS  C   G  V + R V CV+       +DS +CG    P ++  C
Sbjct: 1573 WVVGPWGQCSGPC---GGGV-QRRLVKCVNTQTGLPEEDSDQCGHEAWPESSRPC 1623



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 26/89 (29%), Positives = 34/89 (38%), Gaps = 12/89 (13%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            ++   W+ CS TCG+G   R   C            C    P       ++C    C  W
Sbjct: 1415 WQAGNWSECSTTCGLGAVWRPVRCSSG-----RDEDC---APAGRPQPARRCHLRPCATW 1466

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
              G W+ CS+ C   G  V   R V CVD
Sbjct: 1467 HSGNWSKCSRSCG-GGSSV---RDVQCVD 1491



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 41/126 (32%), Positives = 48/126 (38%), Gaps = 14/126 (11%)

Query: 5    ASQCHLQFGA--EAGLCSKLSELCEHLWCLVDNVC--TTMMRPAAPGTTCGPDMWCQNQT 60
            A +CHL+  A   +G  SK S  C     + D  C  T  +RP  P   C P        
Sbjct: 1455 ARRCHLRPCATWHSGNWSKCSRSCGGGSSVRDVQCVDTRDLRPLRP-FHCQPGP----AK 1509

Query: 61   CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
              A  P  A     W   S W ECS  CG G   Q R    PEP         + +R   
Sbjct: 1510 PPAHRPCGAQPCLSWYT-SSWRECSEACGGG--EQQRLVTCPEPGLCEEALRPNTTR--P 1564

Query: 121  CNTDPC 126
            CNT PC
Sbjct: 1565 CNTHPC 1570



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 1/31 (3%)

Query: 71   RDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            R+ GW     WSECS TCG G   +   C++
Sbjct: 1411 RNAGWQA-GNWSECSTTCGLGAVWRPVRCSS 1440


>AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein.
          Length = 1686

 Score =  364 bits (896), Expect = e-100
 Identities = 177/481 (36%), Positives = 251/481 (52%), Gaps = 22/481 (4%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQT 60
           ++D + QC LQ+GA +  C  +  +C  LWC V   C + +  A  GT CG + WC +  
Sbjct: 467 LYDVSHQCRLQYGAYSAFCEDMDNVCHTLWCSVGTTCHSKLDAAVDGTRCGENKWCLSGE 526

Query: 61  CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           CV     P   DGGW  WS WS CSR+CG GV +  R+C  P P   G YC+G+R R+++
Sbjct: 527 CVPVGFRPEAVDGGWSGWSAWSICSRSCGMGVQSAERQCTQPTPKYKGRYCVGERKRFRL 586

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEMLG 180
           CN   CP   PSFR VQCS  + M YK + +  WVP  +   PCEL C P +    E L 
Sbjct: 587 CNLQACPAGXPSFRHVQCSHFDAMLYKGQ-LHTWVPVVNDVNPCELHCRPANEYFAEKLR 645

Query: 181 GFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYT 240
             V DGTPC Q   SRD+CI+G+C  VGCD+ +DS   ED CGVC G+G+ C TV G + 
Sbjct: 646 DAVVDGTPCYQVRASRDLCINGICKNVGCDFEIDSGAMEDRCGVCHGNGSTCHTVSGTFE 705

Query: 241 KGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLT-EYFV 299
           +      G+ +V +IPAG+R ++IQE     N++++ S    + FLNG        +Y V
Sbjct: 706 E--AEGLGYVDVGLIPAGAREIRIQEVAEAANFLALRSEDPEKYFLNGGWTIQWNGDYQV 763

Query: 300 AGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQR-LHKK--- 355
           AG    Y R  +WE +   GP  E + + Q +F  +  NPGV Y+YT+ ++   H +   
Sbjct: 764 AGTTFTYARRGNWENLTSPGPTKEPVWI-QLLF--QESNPGVHYEYTIHREAGGHDEVPP 820

Query: 356 --HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
              S+    WT C+VTCG G  R+   C+++    V++  C  +  P  Q   ++C +  
Sbjct: 821 PVFSWHYGPWTKCTVTCGRGVQRQNVYCLERQAGPVDEEHCDPLGRPDDQ--QRKCSEQP 878

Query: 414 C-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKV---MNKVVDDSECGQVIKPITTIK 469
           C   WW G W  CS  C   G      R+V C+  V       ++   C  + +P T   
Sbjct: 879 CPARWWAGEWQLCSSSC---GPGGLSRRAVLCIRSVGLDEQSALEPPACEHLPRPPTETP 935

Query: 470 C 470
           C
Sbjct: 936 C 936



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 15/119 (12%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEP-PRHQALMKQCRKPACV 415
            ++    W+ CS +C  G + R  +C+D   R +   + +H +P P      + C    C+
Sbjct: 1465 TWHSGNWSKCSRSCDGGSSVRDVQCVDT--RDLRPLRPFHCQPGPAKPHAHRPCGAQPCL 1522

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
             W+  +W  CS+ C   GE+   +R V C +  +        C + ++P TT  C   P
Sbjct: 1523 SWYTSSWRECSEACG-GGEQ---QRLVTCPEPGL--------CEEALRPNTTRPCNTHP 1569



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 36/121 (29%), Positives = 51/121 (42%), Gaps = 19/121 (15%)

Query: 362 EWTPCSVTCGVG-YTRRYYECIDQ----HQRVVEQSQCYHI-EPPRHQALMKQCRKPACV 415
           EW  CS +CG G  +RR   CI       Q  +E   C H+  PP      +    PA  
Sbjct: 887 EWQLCSSSCGPGGLSRRAVLCIRSVGLDEQSALEPPACEHLPRPPTETPCNRHVPCPAT- 945

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPA 475
            W VG W+ CS  C     E T+ R+V C +           C +  +P + + C+ +P 
Sbjct: 946 -WAVGNWSQCSVTC----GEGTQRRNVLCTNDT------GVPCDEAQQPASEVTCS-LPL 993

Query: 476 C 476
           C
Sbjct: 994 C 994



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 12/90 (13%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
            S++   W+ CS TCG+G   R   C            C    P       ++C    C  
Sbjct: 1414 SWQAGNWSECSTTCGLGAVWRPVRCSSG-----RDEDC---APAGRPQPARRCHLRPCAT 1465

Query: 417  WWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
            W  G W+ CS+ C   G  V   R V CVD
Sbjct: 1466 WHSGNWSKCSRSCD-GGSSV---RDVQCVD 1491



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 15/115 (13%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
            S+  S W  CS  CG G  +R   C        E   C     P      + C    C  
Sbjct: 1523 SWYTSSWRECSEACGGGEQQRLVTC-------PEPGLCEEALRPN---TTRPCNTHPCTQ 1572

Query: 417  WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS-ECGQVIKPITTIKC 470
            W VG W  CS  C   G  V + R V CV+       +DS +CG    P ++  C
Sbjct: 1573 WVVGPWGQCSAPC---GGGV-QRRLVKCVNTQTGLPEEDSDQCGHEAWPESSRPC 1623



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 41/126 (32%), Positives = 50/126 (39%), Gaps = 14/126 (11%)

Query: 5    ASQCHLQFGA--EAGLCSKLSELCEHLWCLVDNVC--TTMMRPAAPGTTCGPDMWCQNQT 60
            A +CHL+  A   +G  SK S  C+    + D  C  T  +RP  P   C P     +  
Sbjct: 1455 ARRCHLRPCATWHSGNWSKCSRSCDGGSSVRDVQCVDTRDLRPLRP-FHCQPGPAKPH-- 1511

Query: 61   CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
              A  P  A     W   S W ECS  CG G   Q R    PEP         + +R   
Sbjct: 1512 --AHRPCGAQPCLSWYT-SSWRECSEACGGG--EQQRLVTCPEPGLCEEALRPNTTR--P 1564

Query: 121  CNTDPC 126
            CNT PC
Sbjct: 1565 CNTHPC 1570



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 2/46 (4%)

Query: 353  HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQ--SQCYH 396
            H    + +  W  CS  CG G  RR  +C++    + E+   QC H
Sbjct: 1568 HPCTQWVVGPWGQCSAPCGGGVQRRLVKCVNTQTGLPEEDSDQCGH 1613


>AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.
          Length = 1117

 Score =  303 bits (744), Expect = 8e-82
 Identities = 171/465 (36%), Positives = 238/465 (51%), Gaps = 34/465 (7%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSELCEHLWCLV-DNVCTTMMRPAAPGTTCGPDM----W 55
           ++DA  QC  Q+GA +  C K  E+C  LWCL   N C T   PAA GT C        W
Sbjct: 483 VYDADEQCRFQYGATSRQC-KYGEVCRELWCLSKSNRCVTNSIPAAEGTLCQTGNIEKGW 541

Query: 56  CQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR 115
           C    CV     P   DGGWGPWS W ECSRTCG GVS+  R C++P P   G YC+G+R
Sbjct: 542 CYQGDCVPFGTWPQSIDGGWGPWSLWGECSRTCGGGVSSSLRHCDSPAPSGGGKYCLGER 601

Query: 116 SRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD-KPCELQCVPRDGT 174
            RY+ CNTDPCP+    FRE QC+  +NMP++ +  + W PY     KPC L C+     
Sbjct: 602 KRYRSCNTDPCPLGSRDFREKQCADFDNMPFRGKYYN-WKPYTGGGVKPCALNCLAEGYN 660

Query: 175 DVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKT 234
                   V DGT C     S D+CI+G C  VGCD I+ SD  ED C VCGGDG+ C  
Sbjct: 661 FYTERAPAVIDGTQCN--ADSLDICINGECKHVGCDNILGSDAREDRCRVCGGDGSTCDA 718

Query: 235 VQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATL 294
           ++G +     R  G+ EV  IP GS +++++E     NYI++ S +    ++NGA     
Sbjct: 719 IEGFFNDSLPR-GGYMEVVQIPRGSVHIEVREVAMSKNYIALKS-EGDDYYINGAWTIDW 776

Query: 295 TEYF-VAGAQAIYERDRDW-EKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL 352
              F VAG    Y+R  D  E +   GP +E++ V   +   + +N G+ Y++ V   R 
Sbjct: 777 PRKFDVAGTAFHYKRPTDEPESLEALGPTSENLIVMVLL---QEQNLGIRYKFNVPITRT 833

Query: 353 -----HKKHSYRLSEWTPCSVTCGVGYTRRYYEC--IDQHQRVVEQSQC-YHIEPPRHQA 404
                    ++    W+ CS TC  G  R+   C  +D +  +V+ + C    +PP +Q 
Sbjct: 834 GSGDNEVGFTWNHQPWSECSATCAGGVQRQEVVCKRLDDNS-IVQNNYCDPDSKPPENQ- 891

Query: 405 LMKQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKV 448
             + C    C   W++G W  CSK C    +   + R+V C+ K+
Sbjct: 892 --RACNTEPCPPEWFIGDWLECSKTC----DGGMRTRAVLCIRKI 930



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 5/113 (4%)

Query: 360  LSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWV 419
            + +W  CS TC  G   R   CI +     E++  Y           + C   +C   WV
Sbjct: 905  IGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPVEKEPCNNQSCPPQWV 964

Query: 420  GA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCA 471
               W+ C+  C  PG    K R V C    ++K    ++C +  KP   I+C+
Sbjct: 965  ALDWSECTPKCG-PG---FKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCS 1013



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 13/112 (11%)

Query: 362  EWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQC-YHIEPP-RHQALMKQCRKPACVHWW 418
            +W+ C+  CG G+  R   C      +    +QC    +PP R +  + +C  P    W 
Sbjct: 967  DWSECTPKCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSLGRCPPP---RWV 1023

Query: 419  VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             G W  CS  C + G+++   R+V C+          S+C + ++P +  +C
Sbjct: 1024 TGDWGQCSAQCGL-GQQM---RTVQCLSYTGQA---SSDCLETVRPPSMQQC 1068


>AF140675-1|AAD56358.1|  997|Homo sapiens zinc metalloprotease
           ADAMTS7 protein.
          Length = 997

 Score =  303 bits (744), Expect = 8e-82
 Identities = 135/335 (40%), Positives = 185/335 (55%), Gaps = 4/335 (1%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQT 60
           ++D + QC LQ+GA +  C  +  +C  LWC V   C + +  A  GT CG + WC +  
Sbjct: 467 LYDVSHQCRLQYGAYSAFCEDMDNVCHTLWCSVGTTCHSKLDAAVDGTRCGENKWCLSGE 526

Query: 61  CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           CV     P   DGGW  WS WS CSR+CG GV +  R+C  P P   G YC+G+R R+++
Sbjct: 527 CVPVGFRPEAVDGGWSGWSAWSICSRSCGMGVQSAERQCTQPTPKYKGRYCVGERKRFRL 586

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEMLG 180
           CN   CP   PSFR VQCS  + M YK + +  WVP  +   PCEL C P +    + L 
Sbjct: 587 CNLQACPAGRPSFRHVQCSHFDAMLYKGQ-LHTWVPVVNDVNPCELHCRPANEYFAKKLR 645

Query: 181 GFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYT 240
             V DGTPC Q   SRD+CI+G+C  VGCD+ +DS   ED CGVC G+G+ C TV G + 
Sbjct: 646 DAVVDGTPCYQVRASRDLCINGICKNVGCDFEIDSGAMEDRCGVCHGNGSTCHTVSGTFE 705

Query: 241 KGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLT-EYFV 299
           +      G+ +V +IPAG+R ++IQE     N++++ S    + FLNG        +Y V
Sbjct: 706 E--AEGLGYVDVGLIPAGAREIRIQEVAEAANFLALRSEDPEKYFLNGGWTIQWNGDYQV 763

Query: 300 AGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRG 334
           AG    Y R  +WE +   GP  E + +     RG
Sbjct: 764 AGTTFTYARRGNWENLTSPGPTKEPVWIQVPASRG 798



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 6/42 (14%)

Query: 338 NPGVTYQYTVDKQRL-HKK-----HSYRLSEWTPCSVTCGVG 373
           NPGV Y+YT+ ++   H +      S+    WT C+VTCG G
Sbjct: 893 NPGVHYEYTIHREAGGHDEVPPPVFSWHYGPWTKCTVTCGRG 934


>BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 18 protein.
          Length = 1221

 Score =  289 bits (709), Expect = 1e-77
 Identities = 167/462 (36%), Positives = 243/462 (52%), Gaps = 29/462 (6%)

Query: 1   MFDAASQCHLQFGAEAGLCSK--LSELCEHLWC-LVDNVCTTMMRPAAPGTTCGPDMWCQ 57
           ++DA +QC  QFGA+A LCS   + ++C+ LWC  V + C T   PAA GT CG  MWC+
Sbjct: 514 IYDADTQCKWQFGAKAKLCSLGFVKDICKSLWCHRVGHRCETKFMPAAEGTVCGLSMWCR 573

Query: 58  NQTCVARTP-SPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
              CV      P P  G W  WS+WSECSRTCG GV  Q R CNNP+P   G +C G   
Sbjct: 574 QGQCVKFGELGPRPIHGQWSAWSKWSECSRTCGGGVKFQERHCNNPKPQYGGIFCPGSSR 633

Query: 117 RYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPY--FDQDKPCELQCVPRDGT 174
            Y++CN +PC  N   FR  QC+ +N+ P++     +W PY   +++  C+L C   +  
Sbjct: 634 IYQLCNINPCNENSLDFRAQQCAEYNSKPFRG-WFYQWKPYTKVEEEDRCKLYCKAENFE 692

Query: 175 DVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKT 234
               + G V DGTPC  +    D+CI GVC  VGCD  + S    DACGVC GD + CK 
Sbjct: 693 FFFAMSGKVKDGTPC--SPNKNDVCIDGVCELVGCDHELGSKAVSDACGVCKGDNSTCKF 750

Query: 235 VQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATL 294
            +G+Y     + + +  V IIPAG+R+++IQE     +Y+++ S  S++ +L G  +   
Sbjct: 751 YKGLYL-NQHKANEYYPVVIIPAGARSIEIQELQVSSSYLAVRSL-SQKYYLTGGWSIDW 808

Query: 295 T-EYFVAGAQAIYERDRDW-EKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDK--- 349
             E+  AG    Y+R  +  E++   GP  E + V++ + +G  +NPG+ ++Y + K   
Sbjct: 809 PGEFPFAGTTFEYQRSFNRPERLYAPGPTNETL-VFEILMQG--KNPGIAWKYALPKVMN 865

Query: 350 --QRLHKKHSYRLS-EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALM 406
                 K+ +Y  S   + CSV+CG GY      C+      V  S C     P  +   
Sbjct: 866 GTPPATKRPAYTWSIVQSECSVSCGGGYINVKAICLRDQNTQVNSSFCSAKTKPVTEP-- 923

Query: 407 KQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDK 447
           K C   +C  +W  G W+ CSK C   G++    R + CV K
Sbjct: 924 KICNAFSCPAYWMPGEWSTCSKAC-AGGQQ---SRKIQCVQK 961



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 9/112 (8%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQ--ALMKQCRKPACV 415
            + L  W+ CS TCG G  +R   C       + +SQC  +  P  Q   ++ +C K + +
Sbjct: 995  WSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQCTSLPRPELQEGCVLGRCPKNSRL 1054

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDK-VMNKVV--DDSECGQVIKP 464
             W   +W+ CS  C +      ++R + C +K    K++   +  C  + KP
Sbjct: 1055 QWVASSWSECSATCGLG----VRKREMKCSEKGFQGKLITFPERRCRNIKKP 1102



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 6/104 (5%)

Query: 362  EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVG 420
            EW+ CS  C  G   R  +C+ +     E++  + + P      ++ C   AC   W +G
Sbjct: 939  EWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPPQWSLG 998

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKP 464
             W+ CSK C   G  V K R + C      + + +S+C  + +P
Sbjct: 999  PWSQCSKTC---GRGVRK-RELLCKGSAA-ETLPESQCTSLPRP 1037



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 16/50 (32%), Positives = 23/50 (46%)

Query: 81   WSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
            W +C+ TCG GV T+S  C      ++           + CNT+ CP  E
Sbjct: 1132 WQQCTVTCGGGVQTRSVHCVQQGRPSSSCLLHQKPPVLRACNTNFCPAPE 1181



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 75   WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNN-----GNYC-IGDRSRYKVCNTDPCPI 128
            W P  EWS CS+ C  G  ++  +C   +P         + C +   ++ + CN+  CP 
Sbjct: 935  WMP-GEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPP 993

Query: 129  NEPSFREVQCSR 140
                    QCS+
Sbjct: 994  QWSLGPWSQCSK 1005



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 12/22 (54%), Positives = 15/22 (68%)

Query: 79   SEWSECSRTCGAGVSTQSRECN 100
            S WSECS TCG GV  +  +C+
Sbjct: 1059 SSWSECSATCGLGVRKREMKCS 1080


>AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.
          Length = 1081

 Score =  288 bits (706), Expect = 3e-77
 Identities = 166/462 (35%), Positives = 243/462 (52%), Gaps = 29/462 (6%)

Query: 1   MFDAASQCHLQFGAEAGLCSK--LSELCEHLWC-LVDNVCTTMMRPAAPGTTCGPDMWCQ 57
           ++DA +QC  QFGA+A LCS   + ++C+ LWC  V + C T   PAA GT CG  MWC+
Sbjct: 513 IYDADTQCKWQFGAKAKLCSLGFVKDICKSLWCHRVGHRCETKFMPAAEGTVCGLSMWCR 572

Query: 58  NQTCVARTP-SPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
              CV      P P  G W  WS+WSECSRTCG GV  Q R CNNP+P   G +C G   
Sbjct: 573 QGQCVKFGELGPRPIHGQWSAWSKWSECSRTCGGGVKFQERHCNNPKPQYGGIFCPGSSR 632

Query: 117 RYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPY--FDQDKPCELQCVPRDGT 174
            Y++CN +PC  N   FR  QC+ +N+ P++     +W PY   +++  C+L C   +  
Sbjct: 633 IYQLCNINPCNENSLDFRAQQCAEYNSKPFRG-WFYQWKPYTKVEEEDRCKLYCKAENFE 691

Query: 175 DVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKT 234
               + G V DGTPC  +    D+CI GVC  VGCD  + S    DACGVC GD + CK 
Sbjct: 692 FFFAMSGKVKDGTPC--SPNKNDVCIDGVCELVGCDHELGSKAVSDACGVCKGDNSTCKF 749

Query: 235 VQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATL 294
            +G+Y     + + +  V +IPAG+R+++IQE     +Y+++ S  S++ +L G  +   
Sbjct: 750 YKGLYL-NQHKANEYYPVVLIPAGARSIEIQELQVSSSYLAVRSL-SQKYYLTGGWSIDW 807

Query: 295 T-EYFVAGAQAIYERDRDW-EKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDK--- 349
             E+  AG    Y+R  +  E++   GP  E + V++ + +G  +NPG+ ++Y + K   
Sbjct: 808 PGEFPFAGTTFEYQRSFNRPERLYAPGPTNETL-VFEILMQG--KNPGIAWKYALPKVMN 864

Query: 350 --QRLHKKHSYRLS-EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALM 406
                 K+ +Y  S   + CSV+CG GY      C+      V  S C     P  +   
Sbjct: 865 GTPPATKRPAYTWSIVQSECSVSCGGGYINVKAICLRDQNTQVNSSFCSAKTKPVTEP-- 922

Query: 407 KQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDK 447
           K C   +C  +W  G W+ CSK C   G++    R + CV K
Sbjct: 923 KICNAFSCPAYWMPGEWSTCSKSC-AGGQQ---SRKIQCVQK 960



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 6/104 (5%)

Query: 362  EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVG 420
            EW+ CS +C  G   R  +C+ +     E++  + + P      ++ C   AC   W +G
Sbjct: 938  EWSTCSKSCAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPPQWSLG 997

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKP 464
             W+ CSK C   G  V K R + C      + + +S+C  + +P
Sbjct: 998  PWSQCSKTC---GRGVRK-RELLCKGSAA-ETLPESQCTSLPRP 1036



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQ--ALMKQCRKPACV 415
            + L  W+ CS TCG G  +R   C       + +SQC  +  P  Q   ++ +C K + +
Sbjct: 994  WSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQCTSLPRPELQEGCVLGRCPKNSRL 1053

Query: 416  HWWVGAWN 423
             W   +W+
Sbjct: 1054 QWVASSWS 1061



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 7/72 (9%)

Query: 75   WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNN-----GNYC-IGDRSRYKVCNTDPCPI 128
            W P  EWS CS++C  G  ++  +C   +P         + C +   ++ + CN+  CP 
Sbjct: 934  WMP-GEWSTCSKSCAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPP 992

Query: 129  NEPSFREVQCSR 140
                    QCS+
Sbjct: 993  QWSLGPWSQCSK 1004


>AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease
           disintegrin 16 with thrombospondin type I motif protein.
          Length = 1072

 Score =  281 bits (690), Expect = 3e-75
 Identities = 161/444 (36%), Positives = 230/444 (51%), Gaps = 26/444 (5%)

Query: 1   MFDAASQCHLQFGAEAGLCSK--LSELCEHLWC-LVDNVCTTMMRPAAPGTTCGPDMWCQ 57
           ++DA +QC  QFG +A LC      ++C+ LWC  +   C T   PAA GT CG DMWC+
Sbjct: 511 LYDANTQCKWQFGEKAKLCMLDFKKDICKALWCHRIGRKCETKFMPAAEGTICGHDMWCR 570

Query: 58  NQTCVAR-TPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
              CV      P P  G W  WS WS CSRTCG GVS +SR C NP+P + G +C G   
Sbjct: 571 GGQCVKYGDEGPKPTHGHWSDWSSWSPCSRTCGGGVSHRSRLCTNPKPSHGGKFCEGSTR 630

Query: 117 RYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYF---DQDKPCELQCVPRDG 173
             K+CN+  CP +   FR  QC+ HN+  ++     +W PY    DQD  C+L C+    
Sbjct: 631 TLKLCNSQKCPRDSVDFRAAQCAEHNSRRFRGRHY-KWKPYTQVEDQDL-CKLYCIAEGF 688

Query: 174 TDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACK 233
                L   V DGTPC +   SR++CI G+C +VGCD ++ SD  ED CGVC G+ +AC 
Sbjct: 689 DFFFSLSNKVKDGTPCSE--DSRNVCIDGICERVGCDNVLGSDAVEDVCGVCNGNNSACT 746

Query: 234 TVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNAT 293
             +G+YTK     + +  +  IP+G+R+++I E     +YIS+ +   RR +LNG     
Sbjct: 747 IHRGLYTK-HHHTNQYYHMVTIPSGARSIRIYEMNVSTSYISVRNA-LRRYYLNGHWTVD 804

Query: 294 LT-EYFVAGAQAIYERD-RDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQR 351
               Y  +G    Y R   + E +  +GP  E + + + +F+G  RNPGV ++Y++ +  
Sbjct: 805 WPGRYKFSGTTFDYRRSYNEPENLIATGPTNETL-IVELLFQG--RNPGVAWEYSMPRLG 861

Query: 352 LHKKHSYRLS-EW----TPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALM 406
             K+   + S  W    + CSV+CG G       C    +  V  S C      R    +
Sbjct: 862 TEKQPPAQPSYTWAIVRSECSVSCGGGQMTVREGCYRDLKFQVNMSFCN--PKTRPVTGL 919

Query: 407 KQCRKPAC-VHWWVGAWNPCSKLC 429
             C+  AC   W VG W+ CS+ C
Sbjct: 920 VPCKVSACPPSWSVGNWSACSRTC 943



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 6/72 (8%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQH----QRVVEQSQCYHIEPPR-HQA-LMKQCRKPACVH 416
            W  CS TCG G+ +R   C   +     +++  + C     PR H+A L+++C KP  + 
Sbjct: 995  WAECSHTCGKGWRKRAVACKSTNPSARAQLLPDAVCTSEPKPRMHEACLLQRCHKPKKLQ 1054

Query: 417  WWVGAWNPCSKL 428
            W V AW+    L
Sbjct: 1055 WLVSAWSQVGAL 1066



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 25/76 (32%), Positives = 30/76 (39%), Gaps = 6/76 (7%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYEC---IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
            S+ +  W+ CS TCG G   R  +C   +      V  S C    P   QA   Q   PA
Sbjct: 930  SWSVGNWSACSRTCGGGAQSRPVQCTRRVHYDSEPVPASLCPQPAPSSRQACNSQSCPPA 989

Query: 414  CVHWWVGAWNPCSKLC 429
               W  G W  CS  C
Sbjct: 990  ---WSAGPWAECSHTC 1002



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 7/57 (12%)

Query: 78  WS--EWSECSRTCGAGVSTQSRECN-----NPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           WS   WS CSRTCG G  ++  +C      + EPV          S  + CN+  CP
Sbjct: 931 WSVGNWSACSRTCGGGAQSRPVQCTRRVHYDSEPVPASLCPQPAPSSRQACNSQSCP 987



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 6/59 (10%)

Query: 46   PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
            P + C        Q C +++  PA     W     W+ECS TCG G   ++  C +  P
Sbjct: 966  PASLCPQPAPSSRQACNSQSCPPA-----WSA-GPWAECSHTCGKGWRKRAVACKSTNP 1018


>AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.
          Length = 1021

 Score =  281 bits (690), Expect = 3e-75
 Identities = 161/444 (36%), Positives = 230/444 (51%), Gaps = 26/444 (5%)

Query: 1   MFDAASQCHLQFGAEAGLCSK--LSELCEHLWC-LVDNVCTTMMRPAAPGTTCGPDMWCQ 57
           ++DA +QC  QFG +A LC      ++C+ LWC  +   C T   PAA GT CG DMWC+
Sbjct: 308 LYDANTQCKWQFGEKAKLCMLDFKKDICKALWCHRIGRKCETKFMPAAEGTICGHDMWCR 367

Query: 58  NQTCVAR-TPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
              CV      P P  G W  WS WS CSRTCG GVS +SR C NP+P + G +C G   
Sbjct: 368 GGQCVKYGDEGPKPTHGHWSDWSSWSPCSRTCGGGVSHRSRLCTNPKPSHGGKFCEGSTR 427

Query: 117 RYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYF---DQDKPCELQCVPRDG 173
             K+CN+  CP +   FR  QC+ HN+  ++     +W PY    DQD  C+L C+    
Sbjct: 428 TLKLCNSQKCPRDSVDFRAAQCAEHNSRRFRGRHY-KWKPYTQVEDQDL-CKLYCIAEGF 485

Query: 174 TDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACK 233
                L   V DGTPC +   SR++CI G+C +VGCD ++ SD  ED CGVC G+ +AC 
Sbjct: 486 DFFFSLSNKVKDGTPCSE--DSRNVCIDGICERVGCDNVLGSDAVEDVCGVCNGNNSACT 543

Query: 234 TVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNAT 293
             +G+YTK     + +  +  IP+G+R+++I E     +YIS+ +   RR +LNG     
Sbjct: 544 IHRGLYTK-HHHTNQYYHMVTIPSGARSIRIYEMNVSTSYISVRNA-LRRYYLNGHWTVD 601

Query: 294 LT-EYFVAGAQAIYERD-RDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQR 351
               Y  +G    Y R   + E +  +GP  E + + + +F+G  RNPGV ++Y++ +  
Sbjct: 602 WPGRYKFSGTTFDYRRSYNEPENLIATGPTNETL-IVELLFQG--RNPGVAWEYSMPRLG 658

Query: 352 LHKKHSYRLS-EW----TPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALM 406
             K+   + S  W    + CSV+CG G       C    +  V  S C      R    +
Sbjct: 659 TEKQPPAQPSYTWAIVRSECSVSCGGGQMTVREGCYRDLKFQVNMSFCN--PKTRPVTGL 716

Query: 407 KQCRKPAC-VHWWVGAWNPCSKLC 429
             C+  AC   W VG W+ CS+ C
Sbjct: 717 VPCKVSACPPSWSVGNWSACSRTC 740



 Score = 58.8 bits (136), Expect = 4e-08
 Identities = 36/123 (29%), Positives = 62/123 (50%), Gaps = 15/123 (12%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQ----RVVEQSQCYHIEPPR-HQA-LMKQCRKPACVH 416
           W  CS TCG G+ +R   C   +     +++  + C     PR H+A L+++C KP  + 
Sbjct: 792 WAECSHTCGKGWRKRAVACKSTNPSARAQLLPDAVCTSEPKPRMHEACLLQRCHKPKKLQ 851

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMN---KVVDDSECGQVIKPITTIK--CA 471
           W V AW+ CS  C    E  T++R + C +K ++   + +   +C  + KP   ++  CA
Sbjct: 852 WLVSAWSQCSVTC----ERGTQKRFLKCAEKYVSGKYRELASKKCSHLPKPSLELERACA 907

Query: 472 DVP 474
            +P
Sbjct: 908 PLP 910



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 3/77 (3%)

Query: 56  CQNQTCVARTPSPA--PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIG 113
           C    C    P  A  P  G W   S WS+C+ +CG GV T+S +C       +G     
Sbjct: 906 CAPLPCPRHPPFAAAGPSRGSWFA-SPWSQCTASCGGGVQTRSVQCLAGGRPASGCLLHQ 964

Query: 114 DRSRYKVCNTDPCPINE 130
             S    CNT  CPI E
Sbjct: 965 KPSASLACNTHFCPIAE 981



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 25/76 (32%), Positives = 30/76 (39%), Gaps = 6/76 (7%)

Query: 357 SYRLSEWTPCSVTCGVGYTRRYYEC---IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           S+ +  W+ CS TCG G   R  +C   +      V  S C    P   QA   Q   PA
Sbjct: 727 SWSVGNWSACSRTCGGGAQSRPVQCTRRVHYDSEPVPASLCPQPAPSSRQACNSQSCPPA 786

Query: 414 CVHWWVGAWNPCSKLC 429
              W  G W  CS  C
Sbjct: 787 ---WSAGPWAECSHTC 799



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 24/115 (20%)

Query: 350 QRLHK--KHSYRLSEWTPCSVTCGVGYTRRYYECIDQH----QRVVEQSQCYHIEPPRHQ 403
           QR HK  K  + +S W+ CSVTC  G  +R+ +C +++     R +   +C H+  P  +
Sbjct: 842 QRCHKPKKLQWLVSAWSQCSVTCERGTQKRFLKCAEKYVSGKYRELASKKCSHLPKPSLE 901

Query: 404 ALMKQCRKPACVH-------------WWVGAWNPCSKLCHMPGEEVTKERSVYCV 445
            L + C    C               W+   W+ C+  C   G  V + RSV C+
Sbjct: 902 -LERACAPLPCPRHPPFAAAGPSRGSWFASPWSQCTASC---GGGV-QTRSVQCL 951



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 7/57 (12%)

Query: 78  WS--EWSECSRTCGAGVSTQSRECN-----NPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           WS   WS CSRTCG G  ++  +C      + EPV          S  + CN+  CP
Sbjct: 728 WSVGNWSACSRTCGGGAQSRPVQCTRRVHYDSEPVPASLCPQPAPSSRQACNSQSCP 784



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 6/59 (10%)

Query: 46  PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           P + C        Q C +++  PA     W     W+ECS TCG G   ++  C +  P
Sbjct: 763 PASLCPQPAPSSRQACNSQSCPPA-----WSA-GPWAECSHTCGKGWRKRAVACKSTNP 815


>AB209515-1|BAD92752.1|  847|Homo sapiens a disintegrin-like and
           metalloprotease (reprolysin type) with thrombospondin ty
           protein.
          Length = 847

 Score =  279 bits (683), Expect = 2e-74
 Identities = 164/490 (33%), Positives = 239/490 (48%), Gaps = 33/490 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLV-DNVCTTMMRPAAPGTTCGPDM----WC 56
           +DA  QC  Q G ++  C K  E+C  LWCL   N C T   PAA GT C        WC
Sbjct: 227 YDADEQCRFQHGVKSRQC-KYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWC 285

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
             + CV     P   DG WGPW+ W +CSRTCG GVS+ SR C++P P   G YC+G+R 
Sbjct: 286 YKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERR 345

Query: 117 RYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD-KPCELQCVPRDGTD 175
           R++ CNTD CP     FREVQCS  +++P++ +   +W  Y     K C L C+      
Sbjct: 346 RHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGK-FYKWKTYRGGGVKACSLTCLAEGFNF 404

Query: 176 VEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTV 235
                  V DGTPCR    + D+C+SG C  VGCD ++ SD+ ED C VCGGDG+AC+T+
Sbjct: 405 YTERAAAVVDGTPCRP--DTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETI 462

Query: 236 QGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLT 295
           +G+++  +   +G+ +V  IP GS ++ IQ+     +++++   +   + L G       
Sbjct: 463 EGVFSPASP-GAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQ-ESLLLEGLPGTPQP 520

Query: 296 EYF-VAGAQAIYERDRDW-EKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQR-L 352
               +AG      +  D  + +   GP+   + V   +   R   P + Y++     R  
Sbjct: 521 HRLPLAGTTFQLRQGPDQVQSLEALGPINASLIV---MVLARTELPALRYRFNAPIARDS 577

Query: 353 HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQRVVEQSQC-YHIEPPRHQALMKQCR 410
              +S+  + WT CS  C  G   +  EC +Q     V    C  H + P+ Q   + C 
Sbjct: 578 LPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQ---RACN 634

Query: 411 KPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYC---VDKVMNKVVDDSECGQVIKPIT 466
              C   W VG W+ CS+ C    +   + RSV C   V     K +DDS C Q   P+ 
Sbjct: 635 TEPCPPDWVVGNWSLCSRSC----DAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPV- 689

Query: 467 TIKCADVPAC 476
            ++    P C
Sbjct: 690 -LEACHGPTC 698



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 22/81 (27%), Positives = 29/81 (35%), Gaps = 8/81 (9%)

Query: 366 CSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC--VHWWVGAWN 423
           C+ +CG G   R   C     R        H  P        +C    C    W  G W 
Sbjct: 759 CTPSCGPGLRHRVVLCKSADHRATLPPA--HCSPAAKPPATMRCNLRRCPPARWVAGEWG 816

Query: 424 PCSKLCHMPGEEVTKERSVYC 444
            CS  C + G+   ++RSV C
Sbjct: 817 ECSAQCGV-GQ---RQRSVRC 833


>AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptidase
           protein.
          Length = 1077

 Score =  274 bits (673), Expect = 3e-73
 Identities = 163/490 (33%), Positives = 238/490 (48%), Gaps = 33/490 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLV-DNVCTTMMRPAAPGTTCGPDM----WC 56
           +DA  QC  Q G ++  C K  E+C  LWCL   N C T   PAA GT C        WC
Sbjct: 447 YDADEQCRFQHGVKSRQC-KYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWC 505

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
             + CV     P   DG WGPW+ W +CSRTCG GVS+ SR C++P P   G YC+G+R 
Sbjct: 506 YKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERR 565

Query: 117 RYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD-KPCELQCVPRDGTD 175
           R++ CNTD CP     FREVQCS  +++P++ +   +W  Y     K C L  +      
Sbjct: 566 RHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGK-FYKWKTYRGGGVKACSLTSLAEGFNF 624

Query: 176 VEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTV 235
                  V DGTPCR    + D+C+SG C  VGCD ++ SD+ ED C VCGGDG+AC+T+
Sbjct: 625 YTERAAAVVDGTPCRP--DTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETI 682

Query: 236 QGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLT 295
           +G+++  +   +G+ +V  IP GS ++ IQ+     +++++   +   + L G       
Sbjct: 683 EGVFSPASP-GAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQ-ESLLLEGLPGTPQP 740

Query: 296 EYF-VAGAQAIYERDRDW-EKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQR-L 352
               +AG      +  D  + +   GP+   + V   +   R   P + Y++     R  
Sbjct: 741 HRLPLAGTTFQLRQGPDQVQSLEALGPINASLIV---MVLARTELPALRYRFNAPIARDS 797

Query: 353 HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQRVVEQSQC-YHIEPPRHQALMKQCR 410
              +S+  + WT CS  C  G   +  EC +Q     V    C  H + P+ Q   + C 
Sbjct: 798 LPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQ---RACN 854

Query: 411 KPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYC---VDKVMNKVVDDSECGQVIKPIT 466
              C   W VG W+ CS+ C    +   + RSV C   V     K +DDS C Q   P+ 
Sbjct: 855 TEPCPPDWVVGNWSLCSRSC----DAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPV- 909

Query: 467 TIKCADVPAC 476
            ++    P C
Sbjct: 910 -LEACHGPTC 918



 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 11/111 (9%)

Query: 362  EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC--VHWWV 419
            +W+ C+ +CG G   R   C     R        H  P        +C    C    W  
Sbjct: 926  DWSECTPSCGPGLRHRVVLCKSADHRATLPPA--HCSPAAKPPATMRCNLRRCPPARWVA 983

Query: 420  GAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            G W  CS  C + G+   ++RSV C            EC + ++P TT +C
Sbjct: 984  GEWGECSAQCGV-GQ---RQRSVRCTSHTGQA---SHECTEALRPPTTQQC 1027



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 16/51 (31%), Positives = 19/51 (37%), Gaps = 1/51 (1%)

Query: 362  EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKP 412
            EW  CS  CGVG  +R   C   H           + PP  Q    +C  P
Sbjct: 985  EWGECSAQCGVGQRQRSVRC-TSHTGQASHECTEALRPPTTQQCEAKCDSP 1034


>BC036515-1|AAH36515.1|  967|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 1 protein.
          Length = 967

 Score =  264 bits (646), Expect = 6e-70
 Identities = 163/502 (32%), Positives = 238/502 (47%), Gaps = 44/502 (8%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDN----VCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC   FG ++  C   +  C  LWC   +    VC T   P A GT+CG   WC 
Sbjct: 482 YDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQTKHFPWADGTSCGEGKWCI 541

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
           N  CV +T       P  G WG W  W +CSRTCG GV    REC+NP P N G YC G 
Sbjct: 542 NGKCVNKTDRKHFDTPFHGSWGMWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGK 601

Query: 115 RSRYKVCNTDPCPINE-PSFREVQCSRHNNM---PYKNETIDEWVPYFDQDKP---CELQ 167
           R RY+ CN + CP N   +FRE QC  HN      + +    EW+P +    P   C+L 
Sbjct: 602 RVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLI 661

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  +      +L   V DGTPC  +  S  +C+ G C K GCD I+DS  + D CGVCGG
Sbjct: 662 CQAKGIGYFFVLQPKVVDGTPC--STDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGG 719

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEK-----VSPGNYISIGSTKSR 282
           +G+ CK + G     T+ + G+ ++  IP G+ N++++++      + G++++I +    
Sbjct: 720 NGSTCKKISG---SVTSAKPGYHDIITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADG- 775

Query: 283 RMFLNGARNATLTEYFV--AGAQAIYE-RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
              LNG    +  E  +   G    Y       E++R   PL E + + Q +  G    P
Sbjct: 776 TYILNGDYTLSTLEQDIMYKGVVLRYSGSSAALERIRSFSPLKEPLTI-QVLTVGNALRP 834

Query: 340 GVTYQYTVDKQR-----LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC 394
            + Y Y V K++     +    ++ + EW  CS +C +G+ RR  EC D + +    S+C
Sbjct: 835 KIKYTYFVKKKKESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRDINGQ--PASEC 892

Query: 395 YHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVD 454
                P   A  + C    C  W +G W+ CSK C   G+   K+RS+ C+      V+ 
Sbjct: 893 AKEVKP---ASTRPCADHPCPQWQLGEWSSCSKTC---GKGY-KKRSLKCLSH-DGGVLS 944

Query: 455 DSECGQVIKPITTIKCADVPAC 476
              C  + KP   I    +  C
Sbjct: 945 HESCDPLKKPKHFIDFCTMAEC 966


>AP001697-1|BAA95502.1|  967|Homo sapiens metalloprotease with
           thrombospondin type 1 motifs protein.
          Length = 967

 Score =  263 bits (644), Expect = 1e-69
 Identities = 163/502 (32%), Positives = 238/502 (47%), Gaps = 44/502 (8%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDN----VCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC   FG ++  C   +  C  LWC   +    VC T   P A GT+CG   WC 
Sbjct: 482 YDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQTKHFPWADGTSCGEGKWCI 541

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
           N  CV +T       P  G WG W  W +CSRTCG GV    REC+NP P N G YC G 
Sbjct: 542 NGKCVNKTDRKHFDTPFHGSWGMWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGK 601

Query: 115 RSRYKVCNTDPCPINE-PSFREVQCSRHNNM---PYKNETIDEWVPYFDQDKP---CELQ 167
           R RY+ CN + CP N   +FRE QC  HN      + +    EW+P +    P   C+L 
Sbjct: 602 RVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLI 661

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  +      +L   V DGTPC  +  S  +C+ G C K GCD I+DS  + D CGVCGG
Sbjct: 662 CQAKGIGYFFVLQPKVVDGTPC--SPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGG 719

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEK-----VSPGNYISIGSTKSR 282
           +G+ CK + G     T+ + G+ ++  IP G+ N++++++      + G++++I +    
Sbjct: 720 NGSTCKKISG---SVTSAKPGYHDIITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADG- 775

Query: 283 RMFLNGARNATLTEYFV--AGAQAIYE-RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
              LNG    +  E  +   G    Y       E++R   PL E + + Q +  G    P
Sbjct: 776 TYILNGDYTLSTLEQDIMYKGVVLRYSGSSAALERIRSFSPLKEPLTI-QVLTVGNALRP 834

Query: 340 GVTYQYTVDKQR-----LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC 394
            + Y Y V K++     +    ++ + EW  CS +C +G+ RR  EC D + +    S+C
Sbjct: 835 KIKYTYFVKKKKESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRDINGQ--PASEC 892

Query: 395 YHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVD 454
                P   A  + C    C  W +G W+ CSK C   G+   K+RS+ C+      V+ 
Sbjct: 893 AKEVKP---ASTRPCADHPCPQWQLGEWSSCSKTC---GKGY-KKRSLKCLSH-DGGVLS 944

Query: 455 DSECGQVIKPITTIKCADVPAC 476
              C  + KP   I    +  C
Sbjct: 945 HESCDPLKKPKHFIDFCTMAEC 966


>AL162080-1|CAB82413.1|  550|Homo sapiens hypothetical protein
           protein.
          Length = 550

 Score =  263 bits (644), Expect = 1e-69
 Identities = 163/502 (32%), Positives = 238/502 (47%), Gaps = 44/502 (8%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDN----VCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC   FG ++  C   +  C  LWC   +    VC T   P A GT+CG   WC 
Sbjct: 65  YDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQTKHFPWADGTSCGEGKWCI 124

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
           N  CV +T       P  G WG W  W +CSRTCG GV    REC+NP P N G YC G 
Sbjct: 125 NGKCVNKTDRKHFDTPFHGSWGMWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGK 184

Query: 115 RSRYKVCNTDPCPINE-PSFREVQCSRHNNM---PYKNETIDEWVPYFDQDKP---CELQ 167
           R RY+ CN + CP N   +FRE QC  HN      + +    EW+P +    P   C+L 
Sbjct: 185 RVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLI 244

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  +      +L   V DGTPC  +  S  +C+ G C K GCD I+DS  + D CGVCGG
Sbjct: 245 CQAKGIGYFFVLQPKVVDGTPC--SPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGG 302

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEK-----VSPGNYISIGSTKSR 282
           +G+ CK + G     T+ + G+ ++  IP G+ N++++++      + G++++I +    
Sbjct: 303 NGSTCKKISG---SVTSAKPGYHDIITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADG- 358

Query: 283 RMFLNGARNATLTEYFV--AGAQAIYE-RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
              LNG    +  E  +   G    Y       E++R   PL E + + Q +  G    P
Sbjct: 359 TYILNGDYTLSTLEQDIMYKGVVLRYSGSSAALERIRSFSPLKEPLTI-QVLTVGNALRP 417

Query: 340 GVTYQYTVDKQR-----LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC 394
            + Y Y V K++     +    ++ + EW  CS +C +G+ RR  EC D + +    S+C
Sbjct: 418 KIKYTYFVKKKKESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRDINGQ--PASEC 475

Query: 395 YHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVD 454
                P   A  + C    C  W +G W+ CSK C   G+   K+RS+ C+      V+ 
Sbjct: 476 AKEVKP---ASTRPCADHPCPQWQLGEWSSCSKTC---GKGY-KKRSLKCLSH-DGGVLS 527

Query: 455 DSECGQVIKPITTIKCADVPAC 476
              C  + KP   I    +  C
Sbjct: 528 HESCDPLKKPKHFIDFCTMAEC 549


>AF207664-1|AAF23772.1|  967|Homo sapiens matrix metalloprotease
           protein.
          Length = 967

 Score =  263 bits (644), Expect = 1e-69
 Identities = 163/502 (32%), Positives = 238/502 (47%), Gaps = 44/502 (8%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDN----VCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC   FG ++  C   +  C  LWC   +    VC T   P A GT+CG   WC 
Sbjct: 482 YDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQTKHFPWADGTSCGEGKWCI 541

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
           N  CV +T       P  G WG W  W +CSRTCG GV    REC+NP P N G YC G 
Sbjct: 542 NGKCVNKTDRKHFDTPFHGSWGMWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGK 601

Query: 115 RSRYKVCNTDPCPINE-PSFREVQCSRHNNM---PYKNETIDEWVPYFDQDKP---CELQ 167
           R RY+ CN + CP N   +FRE QC  HN      + +    EW+P +    P   C+L 
Sbjct: 602 RVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLI 661

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  +      +L   V DGTPC  +  S  +C+ G C K GCD I+DS  + D CGVCGG
Sbjct: 662 CQAKGIGYFFVLQPKVVDGTPC--SPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGG 719

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEK-----VSPGNYISIGSTKSR 282
           +G+ CK + G     T+ + G+ ++  IP G+ N++++++      + G++++I +    
Sbjct: 720 NGSTCKKISG---SVTSAKPGYHDIITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADG- 775

Query: 283 RMFLNGARNATLTEYFV--AGAQAIYE-RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
              LNG    +  E  +   G    Y       E++R   PL E + + Q +  G    P
Sbjct: 776 TYILNGDYTLSTLEQDIMYKGVVLRYSGSSAALERIRSFSPLKEPLTI-QVLTVGNALRP 834

Query: 340 GVTYQYTVDKQR-----LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC 394
            + Y Y V K++     +    ++ + EW  CS +C +G+ RR  EC D + +    S+C
Sbjct: 835 KIKYTYFVKKKKESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRDINGQ--PASEC 892

Query: 395 YHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVD 454
                P   A  + C    C  W +G W+ CSK C   G+   K+RS+ C+      V+ 
Sbjct: 893 AKEVKP---ASTRPCADHPCPQWQLGEWSSCSKTC---GKGY-KKRSLKCLSH-DGGVLS 944

Query: 455 DSECGQVIKPITTIKCADVPAC 476
              C  + KP   I    +  C
Sbjct: 945 HESCDPLKKPKHFIDFCTMAEC 966


>AF170084-1|AAF15317.1|  967|Homo sapiens metalloproteinase with
           thrombospondin type 1 motifs ADAMTS1 protein.
          Length = 967

 Score =  263 bits (644), Expect = 1e-69
 Identities = 163/502 (32%), Positives = 238/502 (47%), Gaps = 44/502 (8%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDN----VCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC   FG ++  C   +  C  LWC   +    VC T   P A GT+CG   WC 
Sbjct: 482 YDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQTKHFPWADGTSCGEGKWCI 541

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
           N  CV +T       P  G WG W  W +CSRTCG GV    REC+NP P N G YC G 
Sbjct: 542 NGKCVNKTDRKHFDTPFHGNWGMWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGK 601

Query: 115 RSRYKVCNTDPCPINE-PSFREVQCSRHNNM---PYKNETIDEWVPYFDQDKP---CELQ 167
           R RY+ CN + CP N   +FRE QC  HN      + +    EW+P +    P   C+L 
Sbjct: 602 RVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLI 661

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  +      +L   V DGTPC  +  S  +C+ G C K GCD I+DS  + D CGVCGG
Sbjct: 662 CQAKGIGYFFVLQPKVVDGTPC--SPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGG 719

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEK-----VSPGNYISIGSTKSR 282
           +G+ CK + G     T+ + G+ ++  IP G+ N++++++      + G++++I +    
Sbjct: 720 NGSTCKKISG---SVTSAKPGYHDIITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADG- 775

Query: 283 RMFLNGARNATLTEYFV--AGAQAIYE-RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
              LNG    +  E  +   G    Y       E++R   PL E + + Q +  G    P
Sbjct: 776 TYILNGDYTLSTLEQDIMYKGVVLRYSGSSAALERIRSFSPLKEPLTI-QVLTVGNALRP 834

Query: 340 GVTYQYTVDKQR-----LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC 394
            + Y Y V K++     +    ++ + EW  CS +C +G+ RR  EC D + +    S+C
Sbjct: 835 KIKYTYFVKKKKESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRDINGQ--PASEC 892

Query: 395 YHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVD 454
                P   A  + C    C  W +G W+ CSK C   G+   K+RS+ C+      V+ 
Sbjct: 893 AKEVKP---ASTRPCADHPCPQWQLGEWSSCSKTC---GKGY-KKRSLKCLSH-DGGVLS 944

Query: 455 DSECGQVIKPITTIKCADVPAC 476
              C  + KP   I    +  C
Sbjct: 945 HESCDPLKKPKHFIDFCTMAEC 966


>AF060152-1|AAD48080.1|  950|Homo sapiens METH1 protein protein.
          Length = 950

 Score =  263 bits (644), Expect = 1e-69
 Identities = 163/502 (32%), Positives = 238/502 (47%), Gaps = 44/502 (8%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDN----VCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC   FG ++  C   +  C  LWC   +    VC T   P A GT+CG   WC 
Sbjct: 465 YDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQTKHFPWADGTSCGEGKWCI 524

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
           N  CV +T       P  G WG W  W +CSRTCG GV    REC+NP P N G YC G 
Sbjct: 525 NGKCVNKTDRKHFDTPFHGSWGMWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGK 584

Query: 115 RSRYKVCNTDPCPINE-PSFREVQCSRHNNM---PYKNETIDEWVPYFDQDKP---CELQ 167
           R RY+ CN + CP N   +FRE QC  HN      + +    EW+P +    P   C+L 
Sbjct: 585 RVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLI 644

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  +      +L   V DGTPC  +  S  +C+ G C K GCD I+DS  + D CGVCGG
Sbjct: 645 CQAKGIGYFFVLQPKVVDGTPC--SPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGG 702

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEK-----VSPGNYISIGSTKSR 282
           +G+ CK + G     T+ + G+ ++  IP G+ N++++++      + G++++I +    
Sbjct: 703 NGSTCKKISG---SVTSAKPGYHDIITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADG- 758

Query: 283 RMFLNGARNATLTEYFV--AGAQAIYE-RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
              LNG    +  E  +   G    Y       E++R   PL E + + Q +  G    P
Sbjct: 759 TYILNGDYTLSTLEQDIMYKGVVLRYSGSSAALERIRSFSPLKEPLTI-QVLTVGNALRP 817

Query: 340 GVTYQYTVDKQR-----LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC 394
            + Y Y V K++     +    ++ + EW  CS +C +G+ RR  EC D + +    S+C
Sbjct: 818 KIKYTYFVKKKKESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRDINGQ--PASEC 875

Query: 395 YHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVD 454
                P   A  + C    C  W +G W+ CSK C   G+   K+RS+ C+      V+ 
Sbjct: 876 AKEVKP---ASTRPCADHPCPQWQLGEWSSCSKTC---GKGY-KKRSLKCLSH-DGGVLS 927

Query: 455 DSECGQVIKPITTIKCADVPAC 476
              C  + KP   I    +  C
Sbjct: 928 HESCDPLKKPKHFIDFCTMAEC 949


>AB037767-1|BAA92584.1|  999|Homo sapiens KIAA1346 protein protein.
          Length = 999

 Score =  263 bits (644), Expect = 1e-69
 Identities = 163/502 (32%), Positives = 238/502 (47%), Gaps = 44/502 (8%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDN----VCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC   FG ++  C   +  C  LWC   +    VC T   P A GT+CG   WC 
Sbjct: 514 YDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQTKHFPWADGTSCGEGKWCI 573

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
           N  CV +T       P  G WG W  W +CSRTCG GV    REC+NP P N G YC G 
Sbjct: 574 NGKCVNKTDRKHFDTPFHGSWGMWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGK 633

Query: 115 RSRYKVCNTDPCPINE-PSFREVQCSRHNNM---PYKNETIDEWVPYFDQDKP---CELQ 167
           R RY+ CN + CP N   +FRE QC  HN      + +    EW+P +    P   C+L 
Sbjct: 634 RVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKYAGVSPKDRCKLI 693

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  +      +L   V DGTPC  +  S  +C+ G C K GCD I+DS  + D CGVCGG
Sbjct: 694 CQAKGIGYFFVLQPKVVDGTPC--SPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGG 751

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEK-----VSPGNYISIGSTKSR 282
           +G+ CK + G     T+ + G+ ++  IP G+ N++++++      + G++++I +    
Sbjct: 752 NGSTCKKISG---SVTSAKPGYHDIITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADG- 807

Query: 283 RMFLNGARNATLTEYFV--AGAQAIYE-RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
              LNG    +  E  +   G    Y       E++R   PL E + + Q +  G    P
Sbjct: 808 TYILNGDYTLSTLEQDIMYKGVVLRYSGSSAALERIRSFSPLKEPLTI-QVLTVGNALRP 866

Query: 340 GVTYQYTVDKQR-----LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC 394
            + Y Y V K++     +    ++ + EW  CS +C +G+ RR  EC D + +    S+C
Sbjct: 867 KIKYTYFVKKKKESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRDINGQ--PASEC 924

Query: 395 YHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVD 454
                P   A  + C    C  W +G W+ CSK C   G+   K+RS+ C+      V+ 
Sbjct: 925 AKEVKP---ASTRPCADHPCPQWQLGEWSSCSKTC---GKGY-KKRSLKCLSH-DGGVLS 976

Query: 455 DSECGQVIKPITTIKCADVPAC 476
              C  + KP   I    +  C
Sbjct: 977 HESCDPLKKPKHFIDFCTMAEC 998


>AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein.
          Length = 1908

 Score =  262 bits (641), Expect = 2e-69
 Identities = 152/488 (31%), Positives = 229/488 (46%), Gaps = 30/488 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCL----VDNVCTTMMRPAAPGTTCGPDMWCQ 57
           +D   QC L FG  + +C  ++ +C HLWC     +   C T   P A GT CGP M C+
Sbjct: 483 YDGNKQCELAFGPGSQMCPHIN-ICMHLWCTSTEKLHKGCFTQHVPPADGTDCGPGMHCR 541

Query: 58  NQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSR 117
           +  CV +     P +G WGPW  +S CSRTCG G+ + +R CN PEP N GNYC+G R +
Sbjct: 542 HGLCVNKETETRPVNGEWGPWEPYSSCSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMK 601

Query: 118 YKVCNTDPCPINEPSFREVQCSRHNNMPYKNETID---EWVPYFD----QDKPCELQCVP 170
           ++ CNTD CP     FRE QCS  N        I     W+P +     +D+ C+L C  
Sbjct: 602 FRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPSNVRWLPRYSGVGTKDR-CKLYCQV 660

Query: 171 RDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGT 230
                  +L   V DGTPC     + D+C+ G C   GCD +++S  + D CGVCGGD +
Sbjct: 661 AGTNYFYLLKDMVEDGTPC--GTETHDICVQGQCMAAGCDHVLNSSAKIDKCGVCGGDNS 718

Query: 231 ACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPG----NYISIGSTKSRRMFL 286
           +CKT+ G++    +   G++ V  IPAG+ NV I++    G    +Y+++   +   +F 
Sbjct: 719 SCKTITGVF---NSSHYGYNVVVKIPAGATNVDIRQYSYSGQPDDSYLALSDAEGNFLFN 775

Query: 287 -NGARNATLTEYFVAGAQAIYERDRD-WEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQ 344
            N   + +  E  V G    Y    +  E++  +    ++I + + +  G   NP V Y 
Sbjct: 776 GNFLLSTSKKEINVQGTVIEYSGSNNAVERINSTNRQEKEILI-EVLCVGNLYNPDVHYS 834

Query: 345 YTVDKQRLHKKHSY-RLSEWTPCSVTCGVGYTRRYYECIDQHQR-VVEQSQCYHIEPPRH 402
           + +  +      ++     W  C+  C  G  RR   CI +    VV   +C H+  P  
Sbjct: 835 FNIPLEERSDMFTWDPYGPWEGCTKMC-QGLQRRNITCIHKSDHSVVSDKECDHL--PLP 891

Query: 403 QALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVI 462
             + + C     + W V   + CS  C      +      Y + +     VDD  CG  +
Sbjct: 892 SFVTQSCNTDCELRWHVIGKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQL 951

Query: 463 KPITTIKC 470
           KP T   C
Sbjct: 952 KPPTQELC 959



 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 43/115 (37%), Positives = 60/115 (52%), Gaps = 10/115 (8%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIE-PPRHQALMKQCRKPACV 415
            S+    WT CS +CG G   R   CIDQ QR +E + C  ++ PP H+A    CR   C 
Sbjct: 1418 SWHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTNCSQVQKPPTHKA----CRSVRCP 1473

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W   +WN CS  C   G  V ++R VYC  K + +VV++  C Q  +P +  +C
Sbjct: 1474 SWKANSWNECSVTC---GSGV-QQRDVYCRLKGVGQVVEEM-CDQSTRPCSQRRC 1523



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 11/125 (8%)

Query: 352  LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRK 411
            + K   +R   WTPCSV+CG G   RY  C D   R+ ++S C H+  P   A +  C  
Sbjct: 1148 IKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALDRIADESYCAHLPRP---AEIWDCFT 1204

Query: 412  PACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCA 471
            P C  W  G W+PCS  C   G   T  R V C++   ++ +D++ C   ++P+   +C+
Sbjct: 1205 P-CGEWQAGDWSPCSASC---GHGKT-TRQVLCMN--YHQPIDENYCDPEVRPLMEQECS 1257

Query: 472  DVPAC 476
             + AC
Sbjct: 1258 -LAAC 1261



 Score = 62.1 bits (144), Expect = 4e-09
 Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 8/118 (6%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
            S+  SEW+ C VTCG G  +R   C      V   S  +     + ++L   C    C  
Sbjct: 1022 SWAASEWSECLVTCGKGTKQRQVWC---QLNVDHLSDGFCNSSTKPESL-SPCELHTCAS 1077

Query: 417  WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
            W VG W PC+  C   G ++   R V CV+++ + V++D+EC +  +P     C   P
Sbjct: 1078 WQVGPWGPCTTTCG-HGYQM---RDVKCVNELASAVLEDTECHEASRPSDRQSCVLTP 1131



 Score = 61.3 bits (142), Expect = 7e-09
 Identities = 38/118 (32%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRH--QALMKQCRKPACV 415
            +    W  CS TCG G   R   C   + +++E   C  +  P    Q  M  C  PA V
Sbjct: 1360 WNYGNWGECSQTCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHAC--PADV 1417

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADV 473
             W    W  CS  C     +  K R V+C+D+   K ++D+ C QV KP T   C  V
Sbjct: 1418 SWHQEPWTSCSASC----GKGRKYREVFCIDQFQRK-LEDTNCSQVQKPPTHKACRSV 1470



 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 22/136 (16%)

Query: 352  LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQRVVEQSQCYHIEPP--RHQALMKQ 408
            LH   S+++  W PC+ TCG GY  R  +C+++    V+E ++C+    P  R   ++  
Sbjct: 1072 LHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTP 1131

Query: 409  CR---------KPACV-----HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVD 454
            C           P  +      W  G+W PCS  C       T+ R V C D  ++++ D
Sbjct: 1132 CSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSC----GRGTQARYVSCRD-ALDRIAD 1186

Query: 455  DSECGQVIKPITTIKC 470
            +S C  + +P     C
Sbjct: 1187 ESYCAHLPRPAEIWDC 1202



 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 10/115 (8%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
            + +R   W  CS +C  G   R   C D++ +    S C     P     ++QC    C 
Sbjct: 1304 NQWRTGPWGQCSSSCSGGLQHRAVVCQDENGQ--SASYCDAASKPPE---LQQCGPGPCP 1358

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  G W  CS+ C   G  + K R V C      ++++D  C  V KP + I+C
Sbjct: 1359 QWNYGNWGECSQTC---GGGI-KSRLVIC-QFPNGQILEDHNCEIVNKPPSVIQC 1408



 Score = 48.0 bits (109), Expect = 7e-05
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 10/113 (8%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +  SEW+ CS +CG G   R   C++     +  ++C  +     +   + C + +C  W
Sbjct: 968  WHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELS----RVTRENCNEFSCPSW 1023

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
                W+ C   C     + TK+R V+C   V +  + D  C    KP +   C
Sbjct: 1024 AASEWSECLVTC----GKGTKQRQVWCQLNVDH--LSDGFCNSSTKPESLSPC 1070



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 12/29 (41%), Positives = 22/29 (75%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQH 385
            ++++ +W+ CSVTCG+G  +R  +CI +H
Sbjct: 1655 TWKVGKWSKCSVTCGIGIMKRQVKCITKH 1683



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 78   WSEWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCIG-DRSRYKVCNTDPCP 127
            +SEWS+CSR+CG G  ++   C NN       N C    R   + CN   CP
Sbjct: 970  YSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSRVTRENCNEFSCP 1021



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 2/38 (5%)

Query: 76   GPWS--EWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
            G W   +WS CS +CG G +T+   C N     + NYC
Sbjct: 1207 GEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYC 1244



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 66   PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            P P P+   W  +  W ECS+TCG G+ ++   C  P
Sbjct: 1354 PGPCPQ---WN-YGNWGECSQTCGGGIKSRLVICQFP 1386



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 53   DMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECN-NPEPVNNGNYC 111
            D  CQ  + V R          W   SEWSEC  TCG G   +   C  N + +++G +C
Sbjct: 1001 DNECQELSRVTRENCNEFSCPSWAA-SEWSECLVTCGKGTKQRQVWCQLNVDHLSDG-FC 1058

Query: 112  IGDRSRYKVCNTDPCPIN 129
                S  K  +  PC ++
Sbjct: 1059 ---NSSTKPESLSPCELH 1073



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 16/113 (14%)

Query: 366  CSVTCGVGYTRRYYECID-----QHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH---W 417
            C+  CG  Y +R   C +     +H+    +   Y   P    + + QC   +C+H   W
Sbjct: 1598 CANNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQCIN-SCLHLATW 1656

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             VG W+ CS  C   G  + K R V C+ K     +    C   +KP    KC
Sbjct: 1657 KVGKWSKCSVTC---GIGIMK-RQVKCITK---HGLSSDLCLNHLKPGAQKKC 1702



 Score = 31.5 bits (68), Expect = 6.7
 Identities = 16/62 (25%), Positives = 26/62 (41%), Gaps = 4/62 (6%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC--IGDRSRYKVCNTDP 125
            P+ R   W     W +CS +C  G+  ++  C + E   + +YC         + C   P
Sbjct: 1299 PSVRGNQWRT-GPWGQCSSSCSGGLQHRAVVCQD-ENGQSASYCDAASKPPELQQCGPGP 1356

Query: 126  CP 127
            CP
Sbjct: 1357 CP 1358


>AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.
          Length = 1207

 Score =  259 bits (635), Expect = 1e-68
 Identities = 144/465 (30%), Positives = 227/465 (48%), Gaps = 34/465 (7%)

Query: 2    FDAASQCHLQFGAEAGLCSKLSE-LCEHLWCLVDNV--CTTMMRPAAPGTTCGPDMWCQN 58
            + A  QC + FG  A  C ++   +C  LWC V+    C T + P   GT C    WC+ 
Sbjct: 563  YTADEQCQILFGPLASFCQEMQHVICTGLWCKVEGEKECRTKLDPPMDGTDCDLGKWCKA 622

Query: 59   QTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRY 118
              C +RT +P    G    WS WS CSRTC AG+S++ R+C  P   +    C G R +Y
Sbjct: 623  GECTSRTSAPEHLAG---EWSLWSPCSRTCSAGISSRERKC--PGLDSEARDCNGPRKQY 677

Query: 119  KVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEM 178
            ++C   PCP   P FR+ QC  ++      + I +W    D++KPC L C P       +
Sbjct: 678  RICENPPCPAGLPGFRDWQCQAYSVRTSSPKHILQWQAVLDEEKPCALFCSPVGKEQPIL 737

Query: 179  LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
            L   V DGT C       D+C +G C KVGCD ++ S   ED CGVC G+G +CK ++G 
Sbjct: 738  LSEKVMDGTSC--GYQGLDICANGRCQKVGCDGLLGSLAREDHCGVCNGNGKSCKIIKGD 795

Query: 239  YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF 298
            +    TR +G+ EV +IPAG+R +K+ E+    +Y+++     ++   +  +      + 
Sbjct: 796  FNH--TRGAGYVEVLVIPAGARRIKVVEEKPAHSYLALRDA-GKQSINSDWKIEHSGAFN 852

Query: 299  VAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHSY 358
            +AG    Y R   WEK+   GP    + +   +F  + +N G+ Y+YT+    L +  S 
Sbjct: 853  LAGTTVHYVRRGLWEKISAKGPTTAPLHLLVLLF--QDQNYGLHYEYTIPSDPLPENQSS 910

Query: 359  RLSE---------WTPCSVTCGVGYTRRYYEC---IDQHQRVVEQSQCYHIEPPRHQALM 406
            +  E         W  C  TCG G  +    C   + ++  +V+  +C ++  P  Q  +
Sbjct: 911  KAPEPLFMWTHTSWEDCDATCGGGERKTTVSCTKIMSKNISIVDNEKCKYLTKPEPQ--I 968

Query: 407  KQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMN 450
            ++C +  C   W +  W PCS+ C   G+ + + R V C  ++ N
Sbjct: 969  RKCNEQPCQTRWMMTEWTPCSRTC---GKGM-QSRQVACTQQLSN 1009



 Score = 41.1 bits (92), Expect = 0.008
 Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 2/49 (4%)

Query: 80   EWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR--SRYKVCNTDPC 126
            +WS+CS TCG G+ ++  +C +     +GN C      + Y+ C+  PC
Sbjct: 1095 DWSKCSITCGKGMQSRVIQCMHKITGRHGNECFSSEKPAAYRPCHLQPC 1143



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 6/68 (8%)

Query: 348  DKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQ-SQCYHIEPPRHQALM 406
            D +   K + +R+ +W+ CS+TCG G   R  +C+  H+      ++C+  E P   A  
Sbjct: 1081 DCEDYSKCYVWRMGDWSKCSITCGKGMQSRVIQCM--HKITGRHGNECFSSEKP---AAY 1135

Query: 407  KQCRKPAC 414
            + C    C
Sbjct: 1136 RPCHLQPC 1143



 Score = 35.9 bits (79), Expect = 0.31
 Identities = 28/108 (25%), Positives = 45/108 (41%), Gaps = 14/108 (12%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAW 422
            W+  SV CG G   R   C +  ++ V  ++      PR     +   K  C  W +G W
Sbjct: 1045 WSEFSVKCGKGIRHRTVRCTNPRKKCVLSTR------PREAEDCEDYSK--CYVWRMGDW 1096

Query: 423  NPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            + CS  C   G+ + + R + C+ K+  +    +EC    KP     C
Sbjct: 1097 SKCSITC---GKGM-QSRVIQCMHKITGR--HGNECFSSEKPAAYRPC 1138


>AF140674-1|AAD56357.1|  860|Homo sapiens zinc metalloprotease
           ADAMTS6 protein.
          Length = 860

 Score =  258 bits (633), Expect = 2e-68
 Identities = 140/363 (38%), Positives = 187/363 (51%), Gaps = 21/363 (5%)

Query: 24  ELCEHLWCLV-DNVCTTMMRPAAPGTTCGPDM----WCQNQTCVARTPSPAPRDGGWGPW 78
           E+C  LWCL   N C T   PAA GT C        WC    CV     P   DGGWGPW
Sbjct: 457 EVCRELWCLSKSNRCVTNSIPAAEGTLCQTGNIEKGWCYQGDCVPFGTWPQSIDGGWGPW 516

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQC 138
           S W ECSRTCG GVS+  R C++P P   G YC+G+R RY+ CNTDPCP+    FRE QC
Sbjct: 517 SLWGECSRTCGGGVSSSLRHCDSPAPSGGGKYCLGERKRYRSCNTDPCPLGSRDFREKQC 576

Query: 139 SRHNNMPYKNETIDEWVPYFDQD-KPCELQCVPRDGTDVEMLGGFVADGTPCRQAIGSRD 197
           +  +NMP++ +  + W PY     KPC L C+             V DGT C     S D
Sbjct: 577 ADFDNMPFRGKYYN-WKPYTGGGVKPCALNCLAEGYNFYTERAPAVIDGTQCN--ADSLD 633

Query: 198 MCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTRQSGFSEVAIIPA 257
           +CI+G C  VGCD I+ SD  ED C VCGG G+ C  ++G +     R  G+ EV  IP 
Sbjct: 634 ICINGECKHVGCDNILGSDAREDRCRVCGGGGSTCDAIEGFFNDSLPR-GGYMEVVQIPR 692

Query: 258 GSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF-VAGAQAIYERDRDW-EKV 315
           GS +++++E     NYI++ S +    ++NGA        F VAG    Y+R  D  E +
Sbjct: 693 GSVHIEVREVAMSKNYIALKS-EGDDYYINGAWTIDWPRKFDVAGTAFHYKRPTDEPESL 751

Query: 316 RISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL-----HKKHSYRLSEWTPCSVTC 370
              GP +E++ V   +   + +N G+ Y++ V   R          ++    W+ CS TC
Sbjct: 752 EALGPTSENLIVMVLL---QEQNLGIRYKFNVPITRTGSGDNEVGFTWNHQPWSECSATC 808

Query: 371 GVG 373
             G
Sbjct: 809 AGG 811


>BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.
          Length = 1205

 Score =  256 bits (628), Expect = 9e-68
 Identities = 154/495 (31%), Positives = 238/495 (48%), Gaps = 37/495 (7%)

Query: 7   QCHLQFGAEAGLCS--KLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG    +C+  +  + C+ LWC   DN   C T   P   GT C    WC    C
Sbjct: 481 QCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHC 540

Query: 62  VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
           + +  +   +DG WG W+++  CSRTCG GV  ++R+CNNP P+N G  C G    Y++C
Sbjct: 541 MWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLC 600

Query: 122 NTDPCPINEPSFREVQC-SRHNNMPYKNETIDEWVPYF--DQDKPCELQCVPRDGTDVEM 178
           NT+ C  +   FR  QC  R+++  Y+N T   W+PY   D  K C L C  ++  DV  
Sbjct: 601 NTEECQKHFEDFRAQQCQQRNSHFEYQN-TKHHWLPYEHPDPKKRCHLYCQSKETGDVAY 659

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C+ G C KVGCD  + S+  ED CGVCGGD + C+TV+G 
Sbjct: 660 MKQLVHDGTHCSYK-DPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGT 718

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF 298
           +T+ T R+ G+ ++  IP G+R+V IQE  +  + ++I +  +    LNG      +  F
Sbjct: 719 FTR-TPRKLGYLKMFDIPPGARHVLIQEDEASPHILAIKNQATGHYILNGKGEEAKSRTF 777

Query: 299 V-AGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHS 357
           +  G +  Y  + D E +   GPL + + +   I +       +TY+Y + +  +   +S
Sbjct: 778 IDLGVEWDYNIEDDIESLHTDGPLHDPV-IVLIIPQENDTRSSLTYKYIIHEDSVPTINS 836

Query: 358 ------------YRLSEWTPCSVTCGVGYTRRYYEC-IDQHQRVVEQSQCYHIEPPRHQA 404
                       + L  W+ CS  CG G+    Y C      ++V +S C   + P+   
Sbjct: 837 NNVIQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPK--P 894

Query: 405 LMKQCRKPACVH--WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVM---NKVVDDSECG 459
           + + C    C H  W    W  C+K C   G ++   R+V C+  ++   N+ V    C 
Sbjct: 895 IRRMCNIQECTHPLWVAEEWEHCTKTCGSSGYQL---RTVRCLQPLLDGTNRSVHSKYC- 950

Query: 460 QVIKPITTIKCADVP 474
              +P +   C  VP
Sbjct: 951 MGDRPESRRPCNRVP 965



 Score = 39.1 bits (87), Expect = 0.033
 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 14/89 (15%)

Query: 362 EWTPCSVTCGV-GYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           EW  C+ TCG  GY  R   C+    D   R V    C    P       + C +  C  
Sbjct: 913 EWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESR----RPCNRVPCPA 968

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYC 444
            W  G W+ CS  C     E T+ R V C
Sbjct: 969 QWKTGPWSECSVTC----GEGTEVRQVLC 993



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 14/91 (15%)

Query: 41   MRPAAPGTTCGP-DMWCQNQTCVARTPS---PAPRDGGWGPWSEWSECSRTCGAGVSTQS 96
            ++P   GT       +C      +R P    P P     GPWSE   CS TCG G   + 
Sbjct: 934  LQPLLDGTNRSVHSKYCMGDRPESRRPCNRVPCPAQWKTGPWSE---CSVTCGEGTEVRQ 990

Query: 97   RECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
              C        G++C G++    + C   PC
Sbjct: 991  VLC------RAGDHCDGEKPESVRACQLPPC 1015


>BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 3 protein.
          Length = 1205

 Score =  256 bits (628), Expect = 9e-68
 Identities = 154/495 (31%), Positives = 238/495 (48%), Gaps = 37/495 (7%)

Query: 7   QCHLQFGAEAGLCS--KLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG    +C+  +  + C+ LWC   DN   C T   P   GT C    WC    C
Sbjct: 481 QCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHC 540

Query: 62  VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
           + +  +   +DG WG W+++  CSRTCG GV  ++R+CNNP P+N G  C G    Y++C
Sbjct: 541 MWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLC 600

Query: 122 NTDPCPINEPSFREVQC-SRHNNMPYKNETIDEWVPYF--DQDKPCELQCVPRDGTDVEM 178
           NT+ C  +   FR  QC  R+++  Y+N T   W+PY   D  K C L C  ++  DV  
Sbjct: 601 NTEECQKHFEDFRAQQCQQRNSHFEYQN-TKHHWLPYEHPDPKKRCHLYCQSKETGDVAY 659

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C+ G C KVGCD  + S+  ED CGVCGGD + C+TV+G 
Sbjct: 660 MKQLVHDGTHCSYK-DPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGT 718

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF 298
           +T+ T R+ G+ ++  IP G+R+V IQE  +  + ++I +  +    LNG      +  F
Sbjct: 719 FTR-TPRKLGYLKMFDIPPGARHVLIQEDEASPHILAIKNQATGHYILNGKGEEAKSRTF 777

Query: 299 V-AGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHS 357
           +  G +  Y  + D E +   GPL + + +   I +       +TY+Y + +  +   +S
Sbjct: 778 IDLGVEWDYNIEDDIESLHTDGPLHDPV-IVLIIPQENDTRSSLTYKYIIHEDSVPTINS 836

Query: 358 ------------YRLSEWTPCSVTCGVGYTRRYYEC-IDQHQRVVEQSQCYHIEPPRHQA 404
                       + L  W+ CS  CG G+    Y C      ++V +S C   + P+   
Sbjct: 837 NNVIQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPK--P 894

Query: 405 LMKQCRKPACVH--WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVM---NKVVDDSECG 459
           + + C    C H  W    W  C+K C   G ++   R+V C+  ++   N+ V    C 
Sbjct: 895 IRRMCNIQECTHPLWVAEEWEHCTKTCGSSGYQL---RTVRCLQPLLDGTNRSVHSKYC- 950

Query: 460 QVIKPITTIKCADVP 474
              +P +   C  VP
Sbjct: 951 MGDRPESRRPCNRVP 965



 Score = 39.1 bits (87), Expect = 0.033
 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 14/89 (15%)

Query: 362 EWTPCSVTCGV-GYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           EW  C+ TCG  GY  R   C+    D   R V    C    P       + C +  C  
Sbjct: 913 EWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESR----RPCNRVPCPA 968

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYC 444
            W  G W+ CS  C     E T+ R V C
Sbjct: 969 QWKTGPWSECSVTC----GEGTEVRQVLC 993



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 14/91 (15%)

Query: 41   MRPAAPGTTCGP-DMWCQNQTCVARTPS---PAPRDGGWGPWSEWSECSRTCGAGVSTQS 96
            ++P   GT       +C      +R P    P P     GPWSE   CS TCG G   + 
Sbjct: 934  LQPLLDGTNRSVHSKYCMGDRPESRRPCNRVPCPAQWKTGPWSE---CSVTCGEGTEVRQ 990

Query: 97   RECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
              C        G++C G++    + C   PC
Sbjct: 991  VLC------RAGDHCDGEKPESVRACQLPPC 1015


>AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and
           metalloprotease with thrombospondin type 1 motifs 20
           protein.
          Length = 1911

 Score =  255 bits (625), Expect = 2e-67
 Identities = 153/491 (31%), Positives = 229/491 (46%), Gaps = 33/491 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCL----VDNVCTTMMRPAAPGTTCGPDMWCQ 57
           +D   QC L FG  + +C  ++ +C HLWC     +   C T   P A GT CGP M C+
Sbjct: 483 YDGNKQCELAFGPGSQMCPHIN-ICMHLWCTSTEKLHKGCFTQHVPPADGTDCGPGMHCR 541

Query: 58  NQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSR 117
           +  CV +     P +G WGPW  +S CSRTCG G+ + +R CN PEP N GNYC+G R +
Sbjct: 542 HGLCVNKETETRPVNGEWGPWEPYSSCSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMK 601

Query: 118 YKVCNTDPCPINEPSFREVQCSRHNNMPYKNETID---EWVPYFD----QDKPCELQCVP 170
           ++ CNTD CP     FRE QCS  N        I     W+P +     +D+ C+L C  
Sbjct: 602 FRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPSNVRWLPRYSGIGTKDR-CKLYCQV 660

Query: 171 RDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGT 230
                  +L   V DGTPC     + D+C+ G C   GCD +++S  + D CGVCGGD +
Sbjct: 661 AGTNYFYLLKDMVEDGTPC--GTETHDICVQGQCMAAGCDHVLNSSAKIDKCGVCGGDNS 718

Query: 231 ACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPG----NYISIGSTKSRRMFL 286
           +CKT+ G++    +   G++ V  IPAG+ NV I++    G    +Y+++   +   +F 
Sbjct: 719 SCKTITGVF---NSSHYGYNVVVKIPAGATNVDIRQYSYSGQPDDSYLALSDAEGNFLFN 775

Query: 287 -NGARNATLTEYFVAGAQAIYERDRDWEKV-RISGPLAEDIK-VYQRIFRGRHRNPGVTY 343
            N   + +  E  V G + + E       V RI+    ++ + + Q +  G   NP V Y
Sbjct: 776 GNFLLSTSKKEINVQGTRTVIEYSGSNNAVERINSTNRQEKELILQVLCVGNLYNPDVHY 835

Query: 344 QYTVDKQRLHKKHSY-RLSEWTPCSVTCGVGYTRRYYECIDQHQR-VVEQSQCYHIEPPR 401
            + +  +      ++     W  C+  C  G  RR   CI +    VV   +C H+  P 
Sbjct: 836 SFNIPLEERSDMFTWDPYGPWEGCTKMC-QGLQRRNITCIHKSDHSVVSDKECDHLPLPS 894

Query: 402 H--QALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECG 459
              Q+    C     +   +   + CS  C      +      Y + +     VDD  CG
Sbjct: 895 FVTQSCNTDCELRGML---LAKKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCG 951

Query: 460 QVIKPITTIKC 470
             +KP T   C
Sbjct: 952 DQLKPPTQELC 962



 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 43/115 (37%), Positives = 60/115 (52%), Gaps = 10/115 (8%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIE-PPRHQALMKQCRKPACV 415
            S+    WT CS +CG G   R   CIDQ QR +E + C  ++ PP H+A    CR   C 
Sbjct: 1421 SWHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTNCSQVQKPPTHKA----CRSVRCP 1476

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W   +WN CS  C   G  V ++R VYC  K + +VV++  C Q  +P +  +C
Sbjct: 1477 SWKANSWNECSVTC---GSGV-QQRDVYCRLKGVGQVVEEM-CDQSTRPCSQRRC 1526



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 11/125 (8%)

Query: 352  LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRK 411
            + K   +R   WTPCSV+CG G   RY  C D   R+ ++S C H+  P   A +  C  
Sbjct: 1151 IKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALDRIADESYCAHLPRP---AEIWDCFT 1207

Query: 412  PACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCA 471
            P C  W  G W+PCS  C   G   T  R V C++   ++ +D++ C   ++P+   +C+
Sbjct: 1208 P-CGEWQAGDWSPCSASC---GHGKT-TRQVLCMN--YHQPIDENYCDPEVRPLMEQECS 1260

Query: 472  DVPAC 476
             + AC
Sbjct: 1261 -LAAC 1264



 Score = 62.1 bits (144), Expect = 4e-09
 Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 8/118 (6%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
            S+  SEW+ C VTCG G  +R   C      V   S  +     + ++L   C    C  
Sbjct: 1025 SWAASEWSECLVTCGKGTKQRQVWC---QLNVDHLSDGFCNSSTKPESL-SPCELHTCAS 1080

Query: 417  WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
            W VG W PC+  C   G ++   R V CV+++ + V++D+EC +  +P     C   P
Sbjct: 1081 WQVGPWGPCTTTCG-HGYQM---RDVKCVNELASAVLEDTECHEASRPSDRQSCVLTP 1134



 Score = 61.3 bits (142), Expect = 7e-09
 Identities = 38/118 (32%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRH--QALMKQCRKPACV 415
            +    W  CS TCG G   R   C   + +++E   C  +  P    Q  M  C  PA V
Sbjct: 1363 WNYGNWGECSQTCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHAC--PADV 1420

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADV 473
             W    W  CS  C     +  K R V+C+D+   K ++D+ C QV KP T   C  V
Sbjct: 1421 SWHQEPWTSCSASC----GKGRKYREVFCIDQFQRK-LEDTNCSQVQKPPTHKACRSV 1473



 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 22/136 (16%)

Query: 352  LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQRVVEQSQCYHIEPP--RHQALMKQ 408
            LH   S+++  W PC+ TCG GY  R  +C+++    V+E ++C+    P  R   ++  
Sbjct: 1075 LHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTP 1134

Query: 409  CR---------KPACV-----HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVD 454
            C           P  +      W  G+W PCS  C       T+ R V C D  ++++ D
Sbjct: 1135 CSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSC----GRGTQARYVSCRD-ALDRIAD 1189

Query: 455  DSECGQVIKPITTIKC 470
            +S C  + +P     C
Sbjct: 1190 ESYCAHLPRPAEIWDC 1205



 Score = 48.0 bits (109), Expect = 7e-05
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 10/113 (8%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +  SEW+ CS +CG G   R   C++     +  ++C  +     +   + C + +C  W
Sbjct: 971  WHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELS----RVTRENCNEFSCPSW 1026

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
                W+ C   C     + TK+R V+C   V +  + D  C    KP +   C
Sbjct: 1027 AASEWSECLVTC----GKGTKQRQVWCQLNVDH--LSDGFCNSSTKPESLSPC 1073



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 10/115 (8%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
            + +R   W  CS +C  G       C D++ +    S C     P     ++QC    C 
Sbjct: 1307 NQWRTGPWGSCSSSCSGGLQHTAVVCQDENGQ--SASYCDAASKPPE---LQQCGPGPCP 1361

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  G W  CS+ C   G  + K R V C      ++++D  C  V KP + I+C
Sbjct: 1362 QWNYGNWGECSQTC---GGGI-KSRLVIC-QFPNGQILEDHNCEIVNKPPSVIQC 1411



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 12/29 (41%), Positives = 22/29 (75%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQH 385
            ++++ +W+ CSVTCG+G  +R  +CI +H
Sbjct: 1658 TWKVGKWSKCSVTCGIGIMKRQVKCITKH 1686



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 78   WSEWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCIG-DRSRYKVCNTDPCP 127
            +SEWS+CSR+CG G  ++   C NN       N C    R   + CN   CP
Sbjct: 973  YSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSRVTRENCNEFSCP 1024



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 2/38 (5%)

Query: 76   GPWS--EWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
            G W   +WS CS +CG G +T+   C N     + NYC
Sbjct: 1210 GEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYC 1247



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 66   PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            P P P+   W  +  W ECS+TCG G+ ++   C  P
Sbjct: 1357 PGPCPQ---WN-YGNWGECSQTCGGGIKSRLVICQFP 1389



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 53   DMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECN-NPEPVNNGNYC 111
            D  CQ  + V R          W   SEWSEC  TCG G   +   C  N + +++G +C
Sbjct: 1004 DNECQELSRVTRENCNEFSCPSWAA-SEWSECLVTCGKGTKQRQVWCQLNVDHLSDG-FC 1061

Query: 112  IGDRSRYKVCNTDPCPIN 129
                S  K  +  PC ++
Sbjct: 1062 ---NSSTKPESLSPCELH 1076



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 16/113 (14%)

Query: 366  CSVTCGVGYTRRYYECID-----QHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH---W 417
            C+  CG  Y +R   C +     +H+    +   Y   P    + + QC   +C+H   W
Sbjct: 1601 CANNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQCIN-SCLHLATW 1659

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             VG W+ CS  C   G  + K R V C+ K     +    C   +KP    KC
Sbjct: 1660 KVGKWSKCSVTC---GIGIMK-RQVKCITK---HGLSSDLCLNHLKPGAQKKC 1705


>AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease
           disintegrin 17, with thrombospondin domains protein.
          Length = 1095

 Score =  252 bits (618), Expect = 2e-66
 Identities = 156/468 (33%), Positives = 211/468 (45%), Gaps = 62/468 (13%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSEL-CEHLWCLV--DNVCTTMMRPAAPGTTCGPDMWCQN 58
           + A  QC + FG  A  C  +  L C  LWCLV  D  C T + P   GT CG D WC+ 
Sbjct: 470 YSANEQCQILFGMNATFCRNMEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRA 529

Query: 59  QTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRY 118
             CV++TP P   DG W PW  WS CSRTCG G   + R+C+NP P   G +C G    +
Sbjct: 530 GECVSKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCPGASVEH 589

Query: 119 KVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEM 178
            VC   PCP   PSFR+ QC  H+ +  K + +   V     DKPCEL C P       +
Sbjct: 590 AVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVV--DDKPCELYCSPLGKESPLL 647

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGTPC       D+C+ G C K+GCD I+ S  +ED CGVC GDG  C  V+G 
Sbjct: 648 VADRVLDGTPCGPY--ETDLCVHGKCQKIGCDGIIGSAAKEDRCGVCSGDGKTCHLVKGD 705

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVS-PGNYISIGSTKSRRMFLNGARNATLTEY 297
           +       S     A+  +G  ++    K+  PG +   G+T                 Y
Sbjct: 706 F-------SHARGTALKDSGKGSINSDWKIELPGEFQIAGTT---------------VRY 743

Query: 298 FVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHS 357
              G          WEK+   GP    + +   +F    ++ G+ Y+YTV   R  +  S
Sbjct: 744 VRRGL---------WEKISAKGPTKLPLHLMVLLF--HDQDYGIHYEYTVPVNRTAENQS 792

Query: 358 -----------YRLSEWTPCSVTCGVGYTRRYYEC---IDQHQRVVEQSQCYHIEPPRHQ 403
                      +  S W  CSV CG G  R    C   +++   +V  S C     P  Q
Sbjct: 793 EPEKPQDSLFIWTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQ 852

Query: 404 ALMKQCRKPACVHWWV-GAWNPCSKLCHMPGEEVTKERSVYCVDKVMN 450
             +++C    C   WV G W+PCS  C    E+  + R V CV ++ N
Sbjct: 853 --VRRCNLHPCQSRWVAGPWSPCSATC----EKGFQHREVTCVYQLQN 894



 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 33/113 (29%), Positives = 49/113 (43%), Gaps = 14/113 (12%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +  SEW+ CS +CG G  +R   C +       Q +C     PR +   +      C  W
Sbjct: 925  WEASEWSQCSASCGKGVWKRTVACTN------SQGKCDASTRPRAEEACED--YSGCYEW 976

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
              G W+ CS  C   G+ + + R V C+ KV  +    SEC  + KP    +C
Sbjct: 977  KTGDWSTCSSTC---GKGL-QSRVVQCMHKVTGR--HGSECPALSKPAPYRQC 1023



 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 31/115 (26%), Positives = 44/115 (38%), Gaps = 12/115 (10%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH-WWVGA 421
           W+PCS TC  G+  R   C+ Q Q     +      P    A ++ C    C+  W    
Sbjct: 870 WSPCSATCEKGFQHREVTCVYQLQNGTHVATRPLYCPGPRPAAVQSCEGQDCLSIWEASE 929

Query: 422 WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
           W+ CS  C   G+ V K R+V C +          +C    +P     C D   C
Sbjct: 930 WSQCSASC---GKGVWK-RTVACTN-------SQGKCDASTRPRAEEACEDYSGC 973



 Score = 37.1 bits (82), Expect = 0.13
 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)

Query: 80   EWSECSRTCGAGVSTQSRECNNPEPVNNGNYC--IGDRSRYKVCNTDPCPINEPSFREVQ 137
            +WS CS TCG G+ ++  +C +     +G+ C  +   + Y+ C  + C  +  +   + 
Sbjct: 980  DWSTCSSTCGKGLQSRVVQCMHKVTGRHGSECPALSKPAPYRQCYQEVCN-DRINANTIT 1038

Query: 138  CSRHNNMPYKNETIDEWVPY 157
              R   + YK  T D+W  Y
Sbjct: 1039 SPRLAALTYKC-TRDQWTVY 1057



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 12/25 (48%), Positives = 17/25 (68%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPE 103
           SEWS+CS +CG GV  ++  C N +
Sbjct: 928 SEWSQCSASCGKGVWKRTVACTNSQ 952



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 6/60 (10%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQ-SQCYHIEPPRHQALMKQCRKPAC 414
            + ++  +W+ CS TCG G   R  +C+  H+      S+C  +  P   A  +QC +  C
Sbjct: 974  YEWKTGDWSTCSSTCGKGLQSRVVQCM--HKVTGRHGSECPALSKP---APYRQCYQEVC 1028


>AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.
          Length = 1201

 Score =  252 bits (618), Expect = 2e-66
 Identities = 153/495 (30%), Positives = 237/495 (47%), Gaps = 37/495 (7%)

Query: 7   QCHLQFGAEAGLCS--KLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG    +C+  +  + C+ LWC   DN   C T   P   GT C    WC    C
Sbjct: 477 QCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHC 536

Query: 62  VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
           + +  +   +DG WG W+++  CSRTCG GV  ++R+CNNP P+N G  C G    Y++C
Sbjct: 537 MWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLC 596

Query: 122 NTDPCPINEPSFREVQC-SRHNNMPYKNETIDEWVPYF--DQDKPCELQCVPRDGTDVEM 178
           NT+ C  +   FR  QC  R+++  Y+N T   W+PY   D  K C L C  ++  DV  
Sbjct: 597 NTEECQKHFEDFRAQQCQQRNSHFEYQN-TKHHWLPYEHPDPKKRCHLYCQSKETGDVAY 655

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C+ G C KVGCD  + S+  ED CGVCGGD + C+TV+G 
Sbjct: 656 MKQLVHDGTHCSYK-DPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGT 714

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF 298
           +T+ T R+ G+ ++  IP G+R+V IQE  +  + ++I +  +    LNG      +  F
Sbjct: 715 FTR-TPRKLGYLKMFDIPPGARHVLIQEDEASPHILAIKNQATGHYILNGKGEEAKSRTF 773

Query: 299 V-AGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHS 357
           +  G +  Y  + D E +   GPL + + +   I +       +TY+Y + +  +   +S
Sbjct: 774 IDLGVEWDYNIEDDIESLHTDGPLHDPV-IVLIIPQENDTRSSLTYKYIIHEDSVPTINS 832

Query: 358 ------------YRLSEWTPCSVTCGVGYTRRYYEC-IDQHQRVVEQSQCYHIEPPRHQA 404
                       + L  W+  S  CG G+    Y C      ++V +S C   + P+   
Sbjct: 833 NNVIQEELDTFEWALKSWSQVSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPK--P 890

Query: 405 LMKQCRKPACVH--WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVM---NKVVDDSECG 459
           + + C    C H  W    W  C+K C   G ++   R+V C+  ++   N+ V    C 
Sbjct: 891 IRRMCNIQECTHPLWVAEEWEHCTKTCGSSGYQL---RTVRCLQPLLDGTNRSVHSKYC- 946

Query: 460 QVIKPITTIKCADVP 474
              +P +   C  VP
Sbjct: 947 MGDRPESRRPCNRVP 961



 Score = 39.1 bits (87), Expect = 0.033
 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 14/89 (15%)

Query: 362 EWTPCSVTCGV-GYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           EW  C+ TCG  GY  R   C+    D   R V    C    P       + C +  C  
Sbjct: 909 EWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESR----RPCNRVPCPA 964

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYC 444
            W  G W+ CS  C     E T+ R V C
Sbjct: 965 QWKTGPWSECSVTC----GEGTEVRQVLC 989



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 14/91 (15%)

Query: 41   MRPAAPGTTCGP-DMWCQNQTCVARTPS---PAPRDGGWGPWSEWSECSRTCGAGVSTQS 96
            ++P   GT       +C      +R P    P P     GPWSE   CS TCG G   + 
Sbjct: 930  LQPLLDGTNRSVHSKYCMGDRPESRRPCNRVPCPAQWKTGPWSE---CSVTCGEGTEVRQ 986

Query: 97   RECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
              C        G++C G++    + C   PC
Sbjct: 987  VLC------RAGDHCDGEKPESVRACQLPPC 1011


>DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif 17 protein.
          Length = 1095

 Score =  252 bits (616), Expect = 3e-66
 Identities = 156/468 (33%), Positives = 210/468 (44%), Gaps = 62/468 (13%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSEL-CEHLWCLV--DNVCTTMMRPAAPGTTCGPDMWCQN 58
           + A  QC + FG  A  C  +  L C  LWCLV  D  C T + P   GT CG D WC+ 
Sbjct: 470 YSANEQCQILFGMNATFCRNMEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRA 529

Query: 59  QTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRY 118
             CV++TP P   DG W PW  WS CSRTCG G     R+C+NP P   G +C G    +
Sbjct: 530 GECVSKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFTQRKCDNPPPGPGGTHCPGASVEH 589

Query: 119 KVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEM 178
            VC   PCP   PSFR+ QC  H+ +  K + +   V     DKPCEL C P       +
Sbjct: 590 AVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVV--DDKPCELYCSPLGKESPLL 647

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGTPC       D+C+ G C K+GCD I+ S  +ED CGVC GDG  C  V+G 
Sbjct: 648 VADRVLDGTPCGPY--ETDLCVHGKCQKIGCDGIIGSAAKEDRCGVCSGDGKTCHLVKGD 705

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVS-PGNYISIGSTKSRRMFLNGARNATLTEY 297
           +       S     A+  +G  ++    K+  PG +   G+T                 Y
Sbjct: 706 F-------SHARGTALKDSGKGSINSDWKIELPGEFQIAGTT---------------VRY 743

Query: 298 FVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHS 357
              G          WEK+   GP    + +   +F    ++ G+ Y+YTV   R  +  S
Sbjct: 744 VRRGL---------WEKISAKGPTKLPLHLMVLLF--HDQDYGIHYEYTVPVNRTAENQS 792

Query: 358 -----------YRLSEWTPCSVTCGVGYTRRYYEC---IDQHQRVVEQSQCYHIEPPRHQ 403
                      +  S W  CSV CG G  R    C   +++   +V  S C     P  Q
Sbjct: 793 EPEKPQDSLFIWTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQ 852

Query: 404 ALMKQCRKPACVHWWV-GAWNPCSKLCHMPGEEVTKERSVYCVDKVMN 450
             +++C    C   WV G W+PCS  C    E+  + R V CV ++ N
Sbjct: 853 --VRRCNLHPCQSRWVAGPWSPCSATC----EKGFQHREVTCVYQLQN 894



 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 33/113 (29%), Positives = 49/113 (43%), Gaps = 14/113 (12%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +  SEW+ CS +CG G  +R   C +       Q +C     PR +   +      C  W
Sbjct: 925  WEASEWSQCSASCGKGVWKRTVACTN------SQGKCDASTRPRAEEACED--YSGCYEW 976

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
              G W+ CS  C   G+ + + R V C+ KV  +    SEC  + KP    +C
Sbjct: 977  KTGDWSTCSSTC---GKGL-QSRVVQCMHKVTGR--HGSECPALSKPAPYRQC 1023



 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 31/115 (26%), Positives = 44/115 (38%), Gaps = 12/115 (10%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH-WWVGA 421
           W+PCS TC  G+  R   C+ Q Q     +      P    A ++ C    C+  W    
Sbjct: 870 WSPCSATCEKGFQHREVTCVYQLQNGTHVATRPLYCPGPRPAAVQSCEGQDCLSIWEASE 929

Query: 422 WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
           W+ CS  C   G+ V K R+V C +          +C    +P     C D   C
Sbjct: 930 WSQCSASC---GKGVWK-RTVACTN-------SQGKCDASTRPRAEEACEDYSGC 973



 Score = 37.1 bits (82), Expect = 0.13
 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)

Query: 80   EWSECSRTCGAGVSTQSRECNNPEPVNNGNYC--IGDRSRYKVCNTDPCPINEPSFREVQ 137
            +WS CS TCG G+ ++  +C +     +G+ C  +   + Y+ C  + C  +  +   + 
Sbjct: 980  DWSTCSSTCGKGLQSRVVQCMHKVTGRHGSECPALSKPAPYRQCYQEVCN-DRINANTIT 1038

Query: 138  CSRHNNMPYKNETIDEWVPY 157
              R   + YK  T D+W  Y
Sbjct: 1039 SPRLAALTYKC-TRDQWTVY 1057



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 12/25 (48%), Positives = 17/25 (68%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPE 103
           SEWS+CS +CG GV  ++  C N +
Sbjct: 928 SEWSQCSASCGKGVWKRTVACTNSQ 952



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 6/60 (10%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQ-SQCYHIEPPRHQALMKQCRKPAC 414
            + ++  +W+ CS TCG G   R  +C+  H+      S+C  +  P   A  +QC +  C
Sbjct: 974  YEWKTGDWSTCSSTCGKGLQSRVVQCM--HKVTGRHGSECPALSKP---APYRQCYQEVC 1028


>AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-proteinase
           protein.
          Length = 1211

 Score =  252 bits (616), Expect = 3e-66
 Identities = 143/462 (30%), Positives = 226/462 (48%), Gaps = 32/462 (6%)

Query: 7   QCHLQFGAEAGLCS--KLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG    +C+  +  + C+ LWC   DN   C T   P   GT C P   C    C
Sbjct: 491 QCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCAPGKHCFKGHC 550

Query: 62  VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
           +  TP    RDG WG WS +  CSRTCG GV  ++R+C+NP P N G  C G    +++C
Sbjct: 551 IWLTPDILKRDGSWGAWSPFGSCSRTCGTGVKFRTRQCDNPHPANGGRTCSGLAYDFQLC 610

Query: 122 NTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQCVPRDGTDVEML 179
           +   CP +   FRE QC + +      +    W+P+  +D  + C L C  R+  +V  +
Sbjct: 611 SRQDCPDSLADFREEQCRQWDLYFEHGDAQHHWLPHEHRDAKERCHLYCESRETGEVVSM 670

Query: 180 GGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIY 239
              V DGT C     +  +C+ G C KVGCD ++ S  +ED CGVCGGD + CK V+G +
Sbjct: 671 KRMVHDGTRCSYK-DAFSLCVRGDCRKVGCDGVIGSSKQEDKCGVCGGDNSHCKVVKGTF 729

Query: 240 TKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGAR--NATLTEY 297
           T+ + ++ G+ ++  IPAG+R++ IQE  +  +++++ + ++ +  LN     +A+   +
Sbjct: 730 TR-SPKKHGYIKMFEIPAGARHLLIQEVDATSHHLAVKNLETGKFILNEENDVDASSKTF 788

Query: 298 FVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKK-- 355
              G +  Y  +   E ++  GPL   I V   +         +TY+Y + +  L+    
Sbjct: 789 IAMGVEWEYRDEDGRETLQTMGPLHGTITVL--VIPVGDTRVSLTYKYMIHEDSLNVDDN 846

Query: 356 ---------HSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQRVVEQSQCYHIEPPRHQAL 405
                    + + L +W+PCS  CG G     Y C  +   ++V +  C  +  P+  A+
Sbjct: 847 NVLEEDSVVYEWALKKWSPCSKPCGGGSQFTKYGCRRRLDHKMVHRGFCAALSKPK--AI 904

Query: 406 MKQCRKPACVH--WWVGAWNPCSKLCHMPGEEVTKERSVYCV 445
            + C    C    W  G W PCS+ C   G +V   RSV C+
Sbjct: 905 RRACNPQECSQPVWVTGEWEPCSQTCGRTGMQV---RSVRCI 943



 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 28/86 (32%), Positives = 34/86 (39%), Gaps = 8/86 (9%)

Query: 362  EWTPCSVTCG-VGYTRRYYECIDQ-HQRVVEQSQCYHIEPPRHQALMKQCRKPACV-HWW 418
            EW PCS TCG  G   R   CI   H          H    R ++  + C +  C   W 
Sbjct: 922  EWEPCSQTCGRTGMQVRSVRCIQPLHDNTTRSVHAKHCNDARPES-RRACSRELCPGRWR 980

Query: 419  VGAWNPCSKLCHMPGEEVTKERSVYC 444
             G W+ CS  C       T+ER V C
Sbjct: 981  AGPWSQCSVTC----GNGTQERPVPC 1002



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 7/62 (11%)

Query: 76   GPW--SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPCP--INE 130
            G W    WS+CS TCG G   +   C   +  ++   C  +R    + C   PCP  I++
Sbjct: 977  GRWRAGPWSQCSVTCGNGTQERPVPCRTAD--DSFGICQEERPETARTCRLGPCPRNISD 1034

Query: 131  PS 132
            PS
Sbjct: 1035 PS 1036


>BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 9 protein.
          Length = 1935

 Score =  249 bits (609), Expect = 2e-65
 Identities = 152/493 (30%), Positives = 231/493 (46%), Gaps = 35/493 (7%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSELCEHLWCL----VDNVCTTMMRPAAPGTTCGPDMWC 56
           +++   QC L FG  + +C  + + C  LWC     V   C T   P A GT C P   C
Sbjct: 514 LYNVNKQCELIFGPGSQVCPYMMQ-CRRLWCNNVNGVHKGCRTQHTPWADGTECEPGKHC 572

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
           +   CV +       DG WG WS +  CSRTCG G+ T  RECN PEP N G YC+G R 
Sbjct: 573 KYGFCVPKEMDVPVTDGSWGSWSPFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRM 632

Query: 117 RYKVCNTDPCPINEPSFREVQCSRHNNMPYK-NETID--EWVPYFD---QDKPCELQCVP 170
           ++K CNT+PC   +  FR+ QC+  +   +  N  +    WVP +        C+L C  
Sbjct: 633 KFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKDRCKLFCRV 692

Query: 171 RDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGT 230
              T    L   V DGTPC Q   + D+C+ G+C + GCD +++S    D CGVCGGD +
Sbjct: 693 AGNTAYYQLRDRVIDGTPCGQ--DTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNS 750

Query: 231 ACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPG-----NYISIGSTKSRRMF 285
           +CKTV G +    T   G++ V  IPAG+ N+ +++    G     NY+++ S+K     
Sbjct: 751 SCKTVAGTF---NTVHYGYNTVVRIPAGATNIDVRQHSFSGETDDDNYLALSSSKG-EFL 806

Query: 286 LNGARNATLTEYFVAGAQAIYE---RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVT 342
           LNG    T+ +  +    A+ E    +   E++  +  + +++ + Q +  G+  NP V 
Sbjct: 807 LNGNFVVTMAKREIRIGNAVVEYSGSETAVERINSTDRIEQEL-LLQVLSVGKLYNPDVR 865

Query: 343 YQYTV---DKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIE 398
           Y + +   DK +    +S+    W  CS  C  G  +R   C  +  Q  V   +C  + 
Sbjct: 866 YSFNIPIEDKPQQFYWNSH--GPWQACSKPC-QGERKRKLVCTRESDQLTVSDQRCDRLP 922

Query: 399 PPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            P H  + + C     + W V + + CS  C +    +    + Y       + VDD  C
Sbjct: 923 QPGH--ITEPCGTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFC 980

Query: 459 GQVIKPITTIKCA 471
               KP    KC+
Sbjct: 981 SSHPKPSNREKCS 993



 Score = 70.1 bits (164), Expect = 2e-11
 Identities = 36/119 (30%), Positives = 58/119 (48%), Gaps = 9/119 (7%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            ++  +W+ C VTCG G+  R   C     R+ ++  C   +P      M+ C++P C  W
Sbjct: 1056 WKSGDWSECLVTCGKGHKHRQVWCQFGEDRLNDR-MC---DPETKPTSMQTCQQPECASW 1111

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
              G W  CS  C   G ++   R+V C+      VVDD++C    +P  T  C ++P+C
Sbjct: 1112 QAGPWGQCSVTCGQ-GYQL---RAVKCIIGTYMSVVDDNDCNAATRPTDTQDC-ELPSC 1165



 Score = 70.1 bits (164), Expect = 2e-11
 Identities = 39/117 (33%), Positives = 53/117 (45%), Gaps = 8/117 (6%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +R   WTPCS TCG G   RY  C D++  V ++S C  +  P      ++C    C  W
Sbjct: 1186 WRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATLPRP---VAKEECSVTPCGQW 1242

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
                W+ CS  C     +    R V CV+   + V+D SEC Q   P T   C+  P
Sbjct: 1243 KALDWSSCSVTC----GQGRATRQVMCVN-YSDHVIDRSECDQDYIPETDQDCSMSP 1294



 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 9/114 (7%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAW 422
            W+ CSV+CG G+ +R   C+ +    +E   C H+  P      ++CR   C  W  GAW
Sbjct: 1450 WSSCSVSCGRGHKQRNVYCMAKDGSHLESDYCKHLAKPHGH---RKCRGGRCPKWKAGAW 1506

Query: 423  NPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
            + CS  C   G  V ++R V C     +K+  ++EC    +P +   C   P C
Sbjct: 1507 SQCSVSC---GRGV-QQRHVGC-QIGTHKIARETECNPYTRPESERDCQG-PRC 1554



 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 11/119 (9%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +R S WT CS +C  G  RR   C++    V++ S+C H E    +  +++C +  C  W
Sbjct: 1001 WRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQE----KVTIQRCSEFPCPQW 1056

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
              G W+ C   C     +  K R V+C  +     ++D  C    KP T+++    P C
Sbjct: 1057 KSGDWSECLVTC----GKGHKHRQVWC--QFGEDRLNDRMCDPETKP-TSMQTCQQPEC 1108



 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 38/134 (28%), Positives = 55/134 (41%), Gaps = 21/134 (15%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYEC-IDQHQRVVEQSQCYHIEPP--RHQALMKQCRKPA 413
            S++   W  CSVTCG GY  R  +C I  +  VV+ + C     P       +  C  P 
Sbjct: 1110 SWQAGPWGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPP 1169

Query: 414  C-------------VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQ 460
                            W  G+W PCS  C     + T+ R V C D+    V D+S C  
Sbjct: 1170 AAPETRRSTYSAPRTQWRFGSWTPCSATC----GKGTRMRYVSCRDE-NGSVADESACAT 1224

Query: 461  VIKPITTIKCADVP 474
            + +P+   +C+  P
Sbjct: 1225 LPRPVAKEECSVTP 1238



 Score = 54.8 bits (126), Expect = 6e-07
 Identities = 31/119 (26%), Positives = 53/119 (44%), Gaps = 10/119 (8%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC--V 415
            ++   W+ CSV+CG G  +R+  C     ++  +++C     P  +   + C+ P C   
Sbjct: 1501 WKAGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESE---RDCQGPRCPLY 1557

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
             W    W  C+K C     E ++ R V CVD   N+ V  + C    +P+    C+  P
Sbjct: 1558 TWRAEEWQECTKTC----GEGSRYRKVVCVDDNKNE-VHGARCDVSKRPVDRESCSLQP 1611



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 38/123 (30%), Positives = 52/123 (42%), Gaps = 17/123 (13%)

Query: 362  EWTPCSVTCGVGYTRRYYECIDQH--QRVVEQS-----QCYHIEPPR-HQALMKQCRKPA 413
            EW+ CSVTCG GY +R   C + +  +   E S      C   +PP  H   ++ C  P 
Sbjct: 1620 EWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDC--PV 1677

Query: 414  CVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADV 473
               W VG W  CS  C +       +RSV C   + N+      C   +KP     C +V
Sbjct: 1678 SATWRVGNWGSCSVSCGVG----VMQRSVQC---LTNEDQPSHLCHTDLKPEERKTCRNV 1730

Query: 474  PAC 476
              C
Sbjct: 1731 YNC 1733



 Score = 48.4 bits (110), Expect = 5e-05
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 4/75 (5%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
            +++R  EW  C+ TCG G   R   C+D ++  V  ++C   +  +     + C    C 
Sbjct: 1557 YTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHGARC---DVSKRPVDRESCSLQPCE 1613

Query: 416  HWWV-GAWNPCSKLC 429
            + W+ G W+ CS  C
Sbjct: 1614 YVWITGEWSECSVTC 1628



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 11/111 (9%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH---WWV 419
            W  C+  CG G   R   C   +        C  ++ P  +   +QC   AC H   W  
Sbjct: 1391 WGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEILDKPPDR---EQCNTHACPHDAAWST 1447

Query: 420  GAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            G W+ CS  C   G    K+R+VYC+ K  + +  D  C  + KP    KC
Sbjct: 1448 GPWSSCSVSCGR-GH---KQRNVYCMAKDGSHLESD-YCKHLAKPHGHRKC 1493



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 5/74 (6%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
            + +R   W  CS TC  G  RR   C D++      + C     P  Q   + C    C 
Sbjct: 1330 NQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTA--NDCVERIKPDEQ---RACESGPCP 1384

Query: 416  HWWVGAWNPCSKLC 429
             W  G W  C+KLC
Sbjct: 1385 QWAYGNWGECTKLC 1398



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 73   GGWGPWSEWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCI-GDRSRYKVCNTDPCP 127
            GGW  +S W+ECS++C  G   +   C N    V + + C   ++   + C+  PCP
Sbjct: 999  GGWR-YSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQRCSEFPCP 1054



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 5/61 (8%)

Query: 76   GPWS--EWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCIGD--RSRYKVCNTDPCPINE 130
            G W   +WS CS TCG G +T+   C N  + V + + C  D      + C+  PCP   
Sbjct: 1240 GQWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQRT 1299

Query: 131  P 131
            P
Sbjct: 1300 P 1300



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 11/26 (42%), Positives = 18/26 (69%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECI 382
            ++R+  W  CSV+CGVG  +R  +C+
Sbjct: 1680 TWRVGNWGSCSVSCGVGVMQRSVQCL 1705



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%)

Query: 61   CVARTPSPAPRDGGWGP---WS--EWSECSRTCGAGVSTQSREC--NNPEPVNNGNYCIG 113
            CV R      R    GP   W+   W EC++ CG G+ T+   C  +N E   + +  I 
Sbjct: 1366 CVERIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEIL 1425

Query: 114  DR-SRYKVCNTDPCP 127
            D+    + CNT  CP
Sbjct: 1426 DKPPDREQCNTHACP 1440


>AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and
           metalloprotease with thrombospondin type 1 motifs 9B
           protein.
          Length = 1935

 Score =  249 bits (609), Expect = 2e-65
 Identities = 152/493 (30%), Positives = 231/493 (46%), Gaps = 35/493 (7%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSELCEHLWCL----VDNVCTTMMRPAAPGTTCGPDMWC 56
           +++   QC L FG  + +C  + + C  LWC     V   C T   P A GT C P   C
Sbjct: 514 LYNVNKQCELIFGPGSQVCPYMMQ-CRRLWCNNVNGVHKGCRTQHTPWADGTECEPGKHC 572

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
           +   CV +       DG WG WS +  CSRTCG G+ T  RECN PEP N G YC+G R 
Sbjct: 573 KYGFCVPKEMDVPVTDGSWGSWSPFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRM 632

Query: 117 RYKVCNTDPCPINEPSFREVQCSRHNNMPYK-NETID--EWVPYFD---QDKPCELQCVP 170
           ++K CNT+PC   +  FR+ QC+  +   +  N  +    WVP +        C+L C  
Sbjct: 633 KFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKDRCKLFCRV 692

Query: 171 RDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGT 230
              T    L   V DGTPC Q   + D+C+ G+C + GCD +++S    D CGVCGGD +
Sbjct: 693 AGNTAYYQLRDRVIDGTPCGQ--DTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNS 750

Query: 231 ACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPG-----NYISIGSTKSRRMF 285
           +CKTV G +    T   G++ V  IPAG+ N+ +++    G     NY+++ S+K     
Sbjct: 751 SCKTVAGTF---NTVHYGYNTVVRIPAGATNIDVRQHSFSGETDDDNYLALSSSKG-EFL 806

Query: 286 LNGARNATLTEYFVAGAQAIYE---RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVT 342
           LNG    T+ +  +    A+ E    +   E++  +  + +++ + Q +  G+  NP V 
Sbjct: 807 LNGNFVVTMAKREIRIGNAVVEYSGSETAVERINSTDRIEQEL-LLQVLSVGKLYNPDVR 865

Query: 343 YQYTV---DKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIE 398
           Y + +   DK +    +S+    W  CS  C  G  +R   C  +  Q  V   +C  + 
Sbjct: 866 YSFNIPIEDKPQQFYWNSH--GPWQACSKPC-QGERKRKLVCTRESDQLTVSDQRCDRLP 922

Query: 399 PPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            P H  + + C     + W V + + CS  C +    +    + Y       + VDD  C
Sbjct: 923 QPGH--ITEPCGTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFC 980

Query: 459 GQVIKPITTIKCA 471
               KP    KC+
Sbjct: 981 SSHPKPSNREKCS 993



 Score = 70.1 bits (164), Expect = 2e-11
 Identities = 39/117 (33%), Positives = 53/117 (45%), Gaps = 8/117 (6%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +R   WTPCS TCG G   RY  C D++  V ++S C  +  P      ++C    C  W
Sbjct: 1186 WRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATLPRP---VAKEECSVTPCGQW 1242

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
                W+ CS  C     +    R V CV+   + V+D SEC Q   P T   C+  P
Sbjct: 1243 KALDWSSCSVTC----GQGRATRQVMCVN-YSDHVIDRSECDQDYIPETDQDCSMSP 1294



 Score = 68.9 bits (161), Expect = 4e-11
 Identities = 36/119 (30%), Positives = 58/119 (48%), Gaps = 9/119 (7%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            ++  +W+ C VTCG G+  R   C     R+ ++  C   +P      M+ C++P C  W
Sbjct: 1056 WKSGDWSECLVTCGKGHKHRQVWCQFGEDRLNDR-MC---DPETKPTSMQTCQQPECASW 1111

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
              G W  CS  C   G ++   R+V C+      VVDD++C    +P  T  C ++P+C
Sbjct: 1112 QAGPWVQCSVTCGQ-GYQL---RAVKCIIGTYMSVVDDNDCNAATRPTDTQDC-ELPSC 1165



 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 9/114 (7%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAW 422
            W+ CSV+CG G+ +R   C+ +    +E   C H+  P      ++CR   C  W  GAW
Sbjct: 1450 WSSCSVSCGRGHKQRNVYCMAKDGSHLESDYCKHLAKPHGH---RKCRGGRCPKWKAGAW 1506

Query: 423  NPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
            + CS  C   G  V ++R V C     +K+  ++EC    +P +   C   P C
Sbjct: 1507 SQCSVSC---GRGV-QQRHVGC-QIGTHKIARETECNPYTRPESERDCQG-PRC 1554



 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 38/134 (28%), Positives = 55/134 (41%), Gaps = 21/134 (15%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYEC-IDQHQRVVEQSQCYHIEPP--RHQALMKQCRKPA 413
            S++   W  CSVTCG GY  R  +C I  +  VV+ + C     P       +  C  P 
Sbjct: 1110 SWQAGPWVQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPP 1169

Query: 414  C-------------VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQ 460
                            W  G+W PCS  C     + T+ R V C D+    V D+S C  
Sbjct: 1170 AAPETRRSTYSAPRTQWRFGSWTPCSATC----GKGTRMRYVSCRDE-NGSVADESACAT 1224

Query: 461  VIKPITTIKCADVP 474
            + +P+   +C+  P
Sbjct: 1225 LPRPVAKEECSVTP 1238



 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 11/119 (9%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +R S WT CS +C  G  RR   C++    V++ S+C H E    +  +++C +  C  W
Sbjct: 1001 WRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQE----KVTIQRCSEFPCPQW 1056

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
              G W+ C   C     +  K R V+C  +     ++D  C    KP T+++    P C
Sbjct: 1057 KSGDWSECLVTC----GKGHKHRQVWC--QFGEDRLNDRMCDPETKP-TSMQTCQQPEC 1108



 Score = 54.8 bits (126), Expect = 6e-07
 Identities = 31/119 (26%), Positives = 53/119 (44%), Gaps = 10/119 (8%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC--V 415
            ++   W+ CSV+CG G  +R+  C     ++  +++C     P  +   + C+ P C   
Sbjct: 1501 WKAGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESE---RDCQGPRCPLY 1557

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
             W    W  C+K C     E ++ R V CVD   N+ V  + C    +P+    C+  P
Sbjct: 1558 TWRAEEWQECTKTC----GEGSRYRKVVCVDDNKNE-VHGARCDVSKRPVDRESCSLQP 1611



 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 38/123 (30%), Positives = 53/123 (43%), Gaps = 17/123 (13%)

Query: 362  EWTPCSVTCGVGYTRRYYECIDQH--QRVVEQS-----QCYHIEPPR-HQALMKQCRKPA 413
            EW+ CSVTCG GY +R   C + +  +   E S      C   +PP  H   +++C  P 
Sbjct: 1620 EWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLREC--PV 1677

Query: 414  CVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADV 473
               W VG W  CS  C +       +RSV C   + N+      C   +KP     C +V
Sbjct: 1678 SATWRVGNWGSCSVSCGVG----VMQRSVQC---LTNEDQPSHLCHTDLKPEERKTCRNV 1730

Query: 474  PAC 476
              C
Sbjct: 1731 YNC 1733



 Score = 48.4 bits (110), Expect = 5e-05
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 4/75 (5%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
            +++R  EW  C+ TCG G   R   C+D ++  V  ++C   +  +     + C    C 
Sbjct: 1557 YTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHGARC---DVSKRPVDRESCSLQPCE 1613

Query: 416  HWWV-GAWNPCSKLC 429
            + W+ G W+ CS  C
Sbjct: 1614 YVWITGEWSECSVTC 1628



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 11/111 (9%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH---WWV 419
            W  C+  CG G   R   C   +        C  ++ P  +   +QC   AC H   W  
Sbjct: 1391 WGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEILDKPPDR---EQCNTHACPHDAAWST 1447

Query: 420  GAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            G W+ CS  C   G    K+R+VYC+ K  + +  D  C  + KP    KC
Sbjct: 1448 GPWSSCSVSCGR-GH---KQRNVYCMAKDGSHLESD-YCKHLAKPHGHRKC 1493



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 5/74 (6%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
            + +R   W  CS TC  G  RR   C D++      + C     P  Q   + C    C 
Sbjct: 1330 NQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTA--NDCVERIKPDEQ---RACESGPCP 1384

Query: 416  HWWVGAWNPCSKLC 429
             W  G W  C+KLC
Sbjct: 1385 QWAYGNWGECTKLC 1398



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 73   GGWGPWSEWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCI-GDRSRYKVCNTDPCP 127
            GGW  +S W+ECS++C  G   +   C N    V + + C   ++   + C+  PCP
Sbjct: 999  GGWR-YSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQRCSEFPCP 1054



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 5/61 (8%)

Query: 76   GPWS--EWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCIGD--RSRYKVCNTDPCPINE 130
            G W   +WS CS TCG G +T+   C N  + V + + C  D      + C+  PCP   
Sbjct: 1240 GQWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQRT 1299

Query: 131  P 131
            P
Sbjct: 1300 P 1300



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 11/26 (42%), Positives = 18/26 (69%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECI 382
            ++R+  W  CSV+CGVG  +R  +C+
Sbjct: 1680 TWRVGNWGSCSVSCGVGVMQRSVQCL 1705



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%)

Query: 61   CVARTPSPAPRDGGWGP---WS--EWSECSRTCGAGVSTQSREC--NNPEPVNNGNYCIG 113
            CV R      R    GP   W+   W EC++ CG G+ T+   C  +N E   + +  I 
Sbjct: 1366 CVERIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEIL 1425

Query: 114  DR-SRYKVCNTDPCP 127
            D+    + CNT  CP
Sbjct: 1426 DKPPDREQCNTHACP 1440


>AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin
           metalloproteinase with thrombospondin repeats protein.
          Length = 1072

 Score =  249 bits (609), Expect = 2e-65
 Identities = 152/493 (30%), Positives = 231/493 (46%), Gaps = 35/493 (7%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSELCEHLWCL----VDNVCTTMMRPAAPGTTCGPDMWC 56
           +++   QC L FG  + +C  + + C  LWC     V   C T   P A GT C P   C
Sbjct: 514 LYNVNKQCELIFGPGSQVCPYMMQ-CRRLWCNNVNGVHKGCRTQHTPWADGTECEPGKHC 572

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
           +   CV +       DG WG WS +  CSRTCG G+ T  RECN PEP N G YC+G R 
Sbjct: 573 KYGFCVPKEMDVPVTDGSWGSWSPFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRM 632

Query: 117 RYKVCNTDPCPINEPSFREVQCSRHNNMPYK-NETID--EWVPYFD---QDKPCELQCVP 170
           ++K CNT+PC   +  FR+ QC+  +   +  N  +    WVP +        C+L C  
Sbjct: 633 KFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKDRCKLFCRV 692

Query: 171 RDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGT 230
              T    L   V DGTPC Q   + D+C+ G+C + GCD +++S    D CGVCGGD +
Sbjct: 693 AGNTAYYQLRDRVIDGTPCGQ--DTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNS 750

Query: 231 ACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPG-----NYISIGSTKSRRMF 285
           +CKTV G +    T   G++ V  IPAG+ N+ +++    G     NY+++ S+K     
Sbjct: 751 SCKTVAGTF---NTVHYGYNTVVRIPAGATNIDVRQHSFSGETDDDNYLALSSSKG-EFL 806

Query: 286 LNGARNATLTEYFVAGAQAIYE---RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVT 342
           LNG    T+ +  +    A+ E    +   E++  +  + +++ + Q +  G+  NP V 
Sbjct: 807 LNGNFVVTMAKREIRIGNAVVEYSGSETAVERINSTDRIEQEL-LLQVLSVGKLYNPDVR 865

Query: 343 YQYTV---DKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIE 398
           Y + +   DK +    +S+    W  CS  C  G  +R   C  +  Q  V   +C  + 
Sbjct: 866 YSFNIPIEDKPQQFYWNSH--GPWQACSKPC-QGERKRKLVCTRESDQLTVSDQRCDRLP 922

Query: 399 PPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            P H  + + C     + W V + + CS  C +    +    + Y       + VDD  C
Sbjct: 923 QPGH--ITEPCGTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFC 980

Query: 459 GQVIKPITTIKCA 471
               KP    KC+
Sbjct: 981 SSHPKPSNREKCS 993



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 5/76 (6%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +R S WT CS +C  G  RR   C++    V++ S+C H E    +  +++C +  C  W
Sbjct: 1001 WRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQE----KVTIQRCSEFPCPQW 1056

Query: 418  WVGAWNPCS-KLCHMP 432
              G W+    + C+ P
Sbjct: 1057 KSGDWSEVRWEGCYFP 1072



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 73   GGWGPWSEWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCI-GDRSRYKVCNTDPCP 127
            GGW  +S W+ECS++C  G   +   C N    V + + C   ++   + C+  PCP
Sbjct: 999  GGWR-YSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQRCSEFPCP 1054


>AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.
          Length = 1471

 Score =  249 bits (609), Expect = 2e-65
 Identities = 152/493 (30%), Positives = 231/493 (46%), Gaps = 35/493 (7%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSELCEHLWCL----VDNVCTTMMRPAAPGTTCGPDMWC 56
           +++   QC L FG  + +C  + + C  LWC     V   C T   P A GT C P   C
Sbjct: 356 LYNVNKQCELIFGPGSQVCPYMMQ-CRRLWCNNVNGVHKGCRTQHTPWADGTECEPGKHC 414

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
           +   CV +       DG WG WS +  CSRTCG G+ T  RECN PEP N G YC+G R 
Sbjct: 415 KYGFCVPKEMDVPVTDGSWGSWSPFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRM 474

Query: 117 RYKVCNTDPCPINEPSFREVQCSRHNNMPYK-NETID--EWVPYFD---QDKPCELQCVP 170
           ++K CNT+PC   +  FR+ QC+  +   +  N  +    WVP +        C+L C  
Sbjct: 475 KFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKDRCKLFCRV 534

Query: 171 RDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGT 230
              T    L   V DGTPC Q   + D+C+ G+C + GCD +++S    D CGVCGGD +
Sbjct: 535 AGNTAYYQLRDRVIDGTPCGQ--DTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNS 592

Query: 231 ACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPG-----NYISIGSTKSRRMF 285
           +CKTV G +    T   G++ V  IPAG+ N+ +++    G     NY+++ S+K     
Sbjct: 593 SCKTVAGTF---NTVHYGYNTVVRIPAGATNIDVRQHSFSGETDDDNYLALSSSKG-EFL 648

Query: 286 LNGARNATLTEYFVAGAQAIYE---RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVT 342
           LNG    T+ +  +    A+ E    +   E++  +  + +++ + Q +  G+  NP V 
Sbjct: 649 LNGNFVVTMAKREIRIGNAVVEYSGSETAVERINSTDRIEQEL-LLQVLSVGKLYNPDVR 707

Query: 343 YQYTV---DKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIE 398
           Y + +   DK +    +S+    W  CS  C  G  +R   C  +  Q  V   +C  + 
Sbjct: 708 YSFNIPIEDKPQQFYWNSH--GPWQACSKPC-QGERKRKLVCTRESDQLTVSDQRCDRLP 764

Query: 399 PPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            P H  + + C     + W V + + CS  C +    +    + Y       + VDD  C
Sbjct: 765 QPGH--ITEPCGTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFC 822

Query: 459 GQVIKPITTIKCA 471
               KP    KC+
Sbjct: 823 SSHPKPSNREKCS 835



 Score = 70.1 bits (164), Expect = 2e-11
 Identities = 36/119 (30%), Positives = 58/119 (48%), Gaps = 9/119 (7%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            ++  +W+ C VTCG G+  R   C     R+ ++  C   +P      M+ C++P C  W
Sbjct: 898  WKSGDWSECLVTCGKGHKHRQVWCQFGEDRLNDR-MC---DPETKPTSMQTCQQPECASW 953

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
              G W  CS  C   G ++   R+V C+      VVDD++C    +P  T  C ++P+C
Sbjct: 954  QAGPWGQCSVTCGQ-GYQL---RAVKCIIGTYMSVVDDNDCNAATRPTDTQDC-ELPSC 1007



 Score = 70.1 bits (164), Expect = 2e-11
 Identities = 39/117 (33%), Positives = 53/117 (45%), Gaps = 8/117 (6%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +R   WTPCS TCG G   RY  C D++  V ++S C  +  P      ++C    C  W
Sbjct: 1028 WRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATLPRP---VAKEECSVTPCGQW 1084

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
                W+ CS  C     +    R V CV+   + V+D SEC Q   P T   C+  P
Sbjct: 1085 KALDWSSCSVTC----GQGRATRQVMCVN-YSDHVIDRSECDQDYIPETDQDCSMSP 1136



 Score = 60.9 bits (141), Expect = 1e-08
 Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 9/114 (7%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAW 422
            W+ CSV+CG G+ +R   C+ +    +E   C H+  P      ++CR   C  W  GAW
Sbjct: 1292 WSSCSVSCGRGHKQRNVYCMAKDGSHLESDYCKHLAKPHGH---RKCRGGRCPKWKAGAW 1348

Query: 423  NPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
            + CS  C   G  V ++R V C     +K+  ++EC    +P +   C   P C
Sbjct: 1349 SQCSVSC---GRGV-QQRHVGC-QIGTHKIARETECNPYTRPESERDCQG-PRC 1396



 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 11/119 (9%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
           +R S WT CS +C  G  RR   C++    V++ S+C H E    +  +++C +  C  W
Sbjct: 843 WRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQE----KVTIQRCSEFPCPQW 898

Query: 418 WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
             G W+ C   C     +  K R V+C  +     ++D  C    KP T+++    P C
Sbjct: 899 KSGDWSECLVTC----GKGHKHRQVWC--QFGEDRLNDRMCDPETKP-TSMQTCQQPEC 950



 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 38/134 (28%), Positives = 55/134 (41%), Gaps = 21/134 (15%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYEC-IDQHQRVVEQSQCYHIEPP--RHQALMKQCRKPA 413
            S++   W  CSVTCG GY  R  +C I  +  VV+ + C     P       +  C  P 
Sbjct: 952  SWQAGPWGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPP 1011

Query: 414  C-------------VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQ 460
                            W  G+W PCS  C     + T+ R V C D+    V D+S C  
Sbjct: 1012 AAPETRRSTYSAPRTQWRFGSWTPCSATC----GKGTRMRYVSCRDE-NGSVADESACAT 1066

Query: 461  VIKPITTIKCADVP 474
            + +P+   +C+  P
Sbjct: 1067 LPRPVAKEECSVTP 1080



 Score = 54.8 bits (126), Expect = 6e-07
 Identities = 31/119 (26%), Positives = 53/119 (44%), Gaps = 10/119 (8%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC--V 415
            ++   W+ CSV+CG G  +R+  C     ++  +++C     P  +   + C+ P C   
Sbjct: 1343 WKAGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESE---RDCQGPRCPLY 1399

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
             W    W  C+K C     E ++ R V CVD   N+ V  + C    +P+    C+  P
Sbjct: 1400 TWRAEEWQECTKTC----GEGSRYRKVVCVDDNKNE-VHGARCDVSKRPVDRESCSLQP 1453



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 11/111 (9%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH---WWV 419
            W  C+  CG G   R   C   +        C  ++ P  +   +QC   AC H   W  
Sbjct: 1233 WGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEILDKPPDR---EQCNTHACPHDAAWST 1289

Query: 420  GAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            G W+ CS  C   G    K+R+VYC+ K  + +  D  C  + KP    KC
Sbjct: 1290 GPWSSCSVSCGR-GH---KQRNVYCMAKDGSHLESD-YCKHLAKPHGHRKC 1335



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 5/74 (6%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
            + +R   W  CS TC  G  RR   C D++      + C     P  Q   + C    C 
Sbjct: 1172 NQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTA--NDCVERIKPDEQ---RACESGPCP 1226

Query: 416  HWWVGAWNPCSKLC 429
             W  G W  C+KLC
Sbjct: 1227 QWAYGNWGECTKLC 1240



 Score = 41.1 bits (92), Expect = 0.008
 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 4/69 (5%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
            +++R  EW  C+ TCG G   R   C+D ++  V  ++C   +  +     + C    C 
Sbjct: 1399 YTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHGARC---DVSKRPVDRESCSLQPCE 1455

Query: 416  HWWV-GAWN 423
            + W+ G W+
Sbjct: 1456 YVWITGEWS 1464



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCI-GDRSRYKVCNTDPCP 127
           GGW  +S W+ECS++C  G   +   C N    V + + C   ++   + C+  PCP
Sbjct: 841 GGWR-YSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQRCSEFPCP 896



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 5/61 (8%)

Query: 76   GPWS--EWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCIGD--RSRYKVCNTDPCPINE 130
            G W   +WS CS TCG G +T+   C N  + V + + C  D      + C+  PCP   
Sbjct: 1082 GQWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQRT 1141

Query: 131  P 131
            P
Sbjct: 1142 P 1142



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%)

Query: 61   CVARTPSPAPRDGGWGP---WS--EWSECSRTCGAGVSTQSREC--NNPEPVNNGNYCIG 113
            CV R      R    GP   W+   W EC++ CG G+ T+   C  +N E   + +  I 
Sbjct: 1208 CVERIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEIL 1267

Query: 114  DR-SRYKVCNTDPCP 127
            D+    + CNT  CP
Sbjct: 1268 DKPPDREQCNTHACP 1282


>AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein.
          Length = 1502

 Score =  248 bits (608), Expect = 2e-65
 Identities = 150/488 (30%), Positives = 227/488 (46%), Gaps = 30/488 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCL----VDNVCTTMMRPAAPGTTCGPDMWCQ 57
           +D   QC L FG  + +C  ++ +C HLWC     +   C T   P A GT CGP M C+
Sbjct: 483 YDGNKQCELAFGPGSQMCPHIN-ICMHLWCTSTEKLHKGCFTQHVPPADGTDCGPGMHCR 541

Query: 58  NQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSR 117
           +  CV +     P +G WGPW  +S CSRTCG G+ + +R CN PEP N GNYC+G R +
Sbjct: 542 HGLCVNKETETRPVNGEWGPWEPYSSCSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMK 601

Query: 118 YKVCNTDPCPINEPSFREVQCSRHNNMPYKNETID---EWVPYFD----QDKPCELQCVP 170
           ++ CNTD CP     FRE QCS  N        I     W+P +     +D+ C+L C  
Sbjct: 602 FRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPSNVRWLPRYSGVGTKDR-CKLYCQV 660

Query: 171 RDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGT 230
                  +L   V DGTPC     S ++  + V    GCD +++S  + D CGVCGGD +
Sbjct: 661 AGTNYFYLLKDMVEDGTPC--GTESYNIDCNCVLKAAGCDHVLNSSAKIDKCGVCGGDNS 718

Query: 231 ACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPG----NYISIGSTKSRRMFL 286
           +CKT+ G++    +   G++ V  IPAG+ NV I++    G    +Y+++   +   +F 
Sbjct: 719 SCKTITGVF---NSSHYGYNVVVKIPAGATNVDIRQYSYSGQPDDSYLALSDAEGNFLFN 775

Query: 287 -NGARNATLTEYFVAGAQAIYERDRD-WEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQ 344
            N   + +  E  V G    Y    +  E++  +    ++I + + +  G   NP V Y 
Sbjct: 776 GNFLLSTSKKEINVQGTVIEYSGSNNAVERINSTNRQEKEILI-EVLCVGNLYNPDVHYS 834

Query: 345 YTVDKQRLHKKHSY-RLSEWTPCSVTCGVGYTRRYYECIDQHQR-VVEQSQCYHIEPPRH 402
           + +  +      ++     W  C+  C  G  RR   CI +    VV   +C H+  P  
Sbjct: 835 FNIPLEERSDMFTWDPYGPWEGCTKMC-QGLQRRNITCIHKSDHSVVSDKECDHL--PLP 891

Query: 403 QALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVI 462
             + + C     + W V   + CS  C      +      Y + +     VDD  CG  +
Sbjct: 892 SFVTQSCNTDCELRWHVIGKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQL 951

Query: 463 KPITTIKC 470
           KP T   C
Sbjct: 952 KPPTQELC 959



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 11/125 (8%)

Query: 352  LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRK 411
            + K   +R   WTPCSV+CG G   RY  C D   R+ ++S C H+  P   A +  C  
Sbjct: 1148 IKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALDRIADESYCAHLPRP---AEIWDCFT 1204

Query: 412  PACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCA 471
            P C  W  G W+PCS  C   G   T  R V C++   ++ +D++ C   ++P+   +C+
Sbjct: 1205 P-CGEWQAGDWSPCSASC---GHGKT-TRQVLCMN--YHQPIDENYCDPEVRPLMEQECS 1257

Query: 472  DVPAC 476
             + AC
Sbjct: 1258 -LAAC 1261



 Score = 62.1 bits (144), Expect = 4e-09
 Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 8/118 (6%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
            S+  SEW+ C VTCG G  +R   C      V   S  +     + ++L   C    C  
Sbjct: 1022 SWAASEWSECLVTCGKGTKQRQVWC---QLNVDHLSDGFCNSSTKPESL-SPCELHTCAS 1077

Query: 417  WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
            W VG W PC+  C   G ++   R V CV+++ + V++D+EC +  +P     C   P
Sbjct: 1078 WQVGPWGPCTTTCG-HGYQM---RDVKCVNELASAVLEDTECHEASRPSDRQSCVLTP 1131



 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 22/136 (16%)

Query: 352  LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQRVVEQSQCYHIEPP--RHQALMKQ 408
            LH   S+++  W PC+ TCG GY  R  +C+++    V+E ++C+    P  R   ++  
Sbjct: 1072 LHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTP 1131

Query: 409  CR---------KPACV-----HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVD 454
            C           P  +      W  G+W PCS  C       T+ R V C D  ++++ D
Sbjct: 1132 CSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSC----GRGTQARYVSCRD-ALDRIAD 1186

Query: 455  DSECGQVIKPITTIKC 470
            +S C  + +P     C
Sbjct: 1187 ESYCAHLPRPAEIWDC 1202



 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 10/115 (8%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
            + +R   W  CS +C  G   R   C D++ +    S C     P     ++QC    C 
Sbjct: 1304 NQWRTGPWGQCSSSCSGGLQHRAVVCQDENGQ--SASYCDAASKPPE---LQQCGPGPCP 1358

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  G W  CS+ C   G  + K R V C      ++++D  C  V KP + I+C
Sbjct: 1359 QWNYGNWGECSQTC---GGGI-KSRLVIC-QFPNGQILEDHNCEIVNKPPSVIQC 1408



 Score = 48.0 bits (109), Expect = 7e-05
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 10/113 (8%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            +  SEW+ CS +CG G   R   C++     +  ++C  +     +   + C + +C  W
Sbjct: 968  WHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELS----RVTRENCNEFSCPSW 1023

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
                W+ C   C     + TK+R V+C   V +  + D  C    KP +   C
Sbjct: 1024 AASEWSECLVTC----GKGTKQRQVWCQLNVDH--LSDGFCNSSTKPESLSPC 1070



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 78   WSEWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCIG-DRSRYKVCNTDPCP 127
            +SEWS+CSR+CG G  ++   C NN       N C    R   + CN   CP
Sbjct: 970  YSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSRVTRENCNEFSCP 1021



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 2/38 (5%)

Query: 76   GPWS--EWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
            G W   +WS CS +CG G +T+   C N     + NYC
Sbjct: 1207 GEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYC 1244



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 66   PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            P P P+   W  +  W ECS+TCG G+ ++   C  P
Sbjct: 1354 PGPCPQ---WN-YGNWGECSQTCGGGIKSRLVICQFP 1386



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 20/67 (29%), Positives = 26/67 (38%), Gaps = 4/67 (5%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRH--QALMKQCRKPACV 415
            +    W  CS TCG G   R   C   + +++E   C  +  P    Q  M  C  PA V
Sbjct: 1360 WNYGNWGECSQTCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHAC--PADV 1417

Query: 416  HWWVGAW 422
             W    W
Sbjct: 1418 SWHQEPW 1424



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 53   DMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECN-NPEPVNNGNYC 111
            D  CQ  + V R          W   SEWSEC  TCG G   +   C  N + +++G +C
Sbjct: 1001 DNECQELSRVTRENCNEFSCPSWAA-SEWSECLVTCGKGTKQRQVWCQLNVDHLSDG-FC 1058

Query: 112  IGDRSRYKVCNTDPCPIN 129
                S  K  +  PC ++
Sbjct: 1059 ---NSSTKPESLSPCELH 1073



 Score = 31.5 bits (68), Expect = 6.7
 Identities = 16/62 (25%), Positives = 26/62 (41%), Gaps = 4/62 (6%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC--IGDRSRYKVCNTDP 125
            P+ R   W     W +CS +C  G+  ++  C + E   + +YC         + C   P
Sbjct: 1299 PSVRGNQWRT-GPWGQCSSSCSGGLQHRAVVCQD-ENGQSASYCDAASKPPELQQCGPGP 1356

Query: 126  CP 127
            CP
Sbjct: 1357 CP 1358


>AL358817-5|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1226

 Score =  242 bits (592), Expect = 2e-63
 Identities = 148/492 (30%), Positives = 221/492 (44%), Gaps = 29/492 (5%)

Query: 7   QCHLQFGA--EAGLCSKLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG+  +  L  +  E C+ LWC   DN   C T   P   GT C P  WC    C
Sbjct: 484 QCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHC 543

Query: 62  VARTPSPA-PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           + ++P     +DGGW  W+++  CSR+CG GV ++SR CNNP P   G  C+G    Y+V
Sbjct: 544 IWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQV 603

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQCVPRDGTDVEM 178
           CN++ CP     FR  QC++ N+          WVPY   D  + CEL C   D  DV  
Sbjct: 604 CNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVF 663

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C  G C  VGCD  V S   +D CGVCGGD + C+TV+G 
Sbjct: 664 MNQVVHDGTRCSYR-DPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGT 722

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLN-GARNATLTEY 297
             K  ++Q+G  ++  IPAG+R+++I+      + I + +  +    LN   + AT   +
Sbjct: 723 LGK-ASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTF 781

Query: 298 FVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL----- 352
              G +     +   E ++ SGPL E I +             + Y+Y + +  L     
Sbjct: 782 TAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGS 841

Query: 353 -------HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQCYHIEPPRHQA 404
                     + + L  W PCS  CG G     Y C  +    +V++  C H + P+   
Sbjct: 842 NNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPK--P 899

Query: 405 LMKQCRKPACVH--WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVI 462
           + ++C +  C    W    W  CS+ C   G +    + +  +    +KV+    C    
Sbjct: 900 IRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAG-D 958

Query: 463 KPITTIKCADVP 474
           +P     C  VP
Sbjct: 959 RPEARRPCLRVP 970



 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 11/117 (9%)

Query: 11   QFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAP 70
            ++GA +  C KL      + CL+    +       P   C  D     + C+ R P PA 
Sbjct: 918  EWGACSRSCGKLGVQTRGIQCLLP--LSNGTHKVMPAKACAGDRPEARRPCL-RVPCPAQ 974

Query: 71   RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
                W     WS+CS TCG G+  +   C      N+  +C GDR    +VC+   C
Sbjct: 975  ----WR-LGAWSQCSATCGEGIQQRQVVCRT--NANSLGHCEGDRPDTVQVCSLPAC 1024



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 12/88 (13%)

Query: 362 EWTPCSVTCG-VGYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           EW  CS +CG +G   R  +C+    +   +V+    C    P   +  +   R P    
Sbjct: 918 EWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCL---RVPCPAQ 974

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYC 444
           W +GAW+ CS  C   GE + ++R V C
Sbjct: 975 WRLGAWSQCSATC---GEGI-QQRQVVC 998



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/24 (45%), Positives = 14/24 (58%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC 381
           +RL  W+ CS TCG G  +R   C
Sbjct: 975 WRLGAWSQCSATCGEGIQQRQVVC 998


>AL358817-4|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1223

 Score =  242 bits (592), Expect = 2e-63
 Identities = 148/492 (30%), Positives = 221/492 (44%), Gaps = 29/492 (5%)

Query: 7   QCHLQFGA--EAGLCSKLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG+  +  L  +  E C+ LWC   DN   C T   P   GT C P  WC    C
Sbjct: 481 QCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHC 540

Query: 62  VARTPSPA-PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           + ++P     +DGGW  W+++  CSR+CG GV ++SR CNNP P   G  C+G    Y+V
Sbjct: 541 IWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQV 600

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQCVPRDGTDVEM 178
           CN++ CP     FR  QC++ N+          WVPY   D  + CEL C   D  DV  
Sbjct: 601 CNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVF 660

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C  G C  VGCD  V S   +D CGVCGGD + C+TV+G 
Sbjct: 661 MNQVVHDGTRCSYR-DPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGT 719

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLN-GARNATLTEY 297
             K  ++Q+G  ++  IPAG+R+++I+      + I + +  +    LN   + AT   +
Sbjct: 720 LGK-ASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTF 778

Query: 298 FVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL----- 352
              G +     +   E ++ SGPL E I +             + Y+Y + +  L     
Sbjct: 779 TAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGS 838

Query: 353 -------HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQCYHIEPPRHQA 404
                     + + L  W PCS  CG G     Y C  +    +V++  C H + P+   
Sbjct: 839 NNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPK--P 896

Query: 405 LMKQCRKPACVH--WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVI 462
           + ++C +  C    W    W  CS+ C   G +    + +  +    +KV+    C    
Sbjct: 897 IRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAG-D 955

Query: 463 KPITTIKCADVP 474
           +P     C  VP
Sbjct: 956 RPEARRPCLRVP 967



 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 11/117 (9%)

Query: 11   QFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAP 70
            ++GA +  C KL      + CL+    +       P   C  D     + C+ R P PA 
Sbjct: 915  EWGACSRSCGKLGVQTRGIQCLLP--LSNGTHKVMPAKACAGDRPEARRPCL-RVPCPAQ 971

Query: 71   RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
                W     WS+CS TCG G+  +   C      N+  +C GDR    +VC+   C
Sbjct: 972  ----WR-LGAWSQCSATCGEGIQQRQVVCRT--NANSLGHCEGDRPDTVQVCSLPAC 1021



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 12/88 (13%)

Query: 362 EWTPCSVTCG-VGYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           EW  CS +CG +G   R  +C+    +   +V+    C    P   +  +   R P    
Sbjct: 915 EWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCL---RVPCPAQ 971

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYC 444
           W +GAW+ CS  C   GE + ++R V C
Sbjct: 972 WRLGAWSQCSATC---GEGI-QQRQVVC 995



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/24 (45%), Positives = 14/24 (58%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC 381
           +RL  W+ CS TCG G  +R   C
Sbjct: 972 WRLGAWSQCSATCGEGIQQRQVVC 995


>AL355344-5|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1226

 Score =  242 bits (592), Expect = 2e-63
 Identities = 148/492 (30%), Positives = 221/492 (44%), Gaps = 29/492 (5%)

Query: 7   QCHLQFGA--EAGLCSKLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG+  +  L  +  E C+ LWC   DN   C T   P   GT C P  WC    C
Sbjct: 484 QCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHC 543

Query: 62  VARTPSPA-PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           + ++P     +DGGW  W+++  CSR+CG GV ++SR CNNP P   G  C+G    Y+V
Sbjct: 544 IWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQV 603

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQCVPRDGTDVEM 178
           CN++ CP     FR  QC++ N+          WVPY   D  + CEL C   D  DV  
Sbjct: 604 CNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVF 663

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C  G C  VGCD  V S   +D CGVCGGD + C+TV+G 
Sbjct: 664 MNQVVHDGTRCSYR-DPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGT 722

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLN-GARNATLTEY 297
             K  ++Q+G  ++  IPAG+R+++I+      + I + +  +    LN   + AT   +
Sbjct: 723 LGK-ASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTF 781

Query: 298 FVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL----- 352
              G +     +   E ++ SGPL E I +             + Y+Y + +  L     
Sbjct: 782 TAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGS 841

Query: 353 -------HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQCYHIEPPRHQA 404
                     + + L  W PCS  CG G     Y C  +    +V++  C H + P+   
Sbjct: 842 NNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPK--P 899

Query: 405 LMKQCRKPACVH--WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVI 462
           + ++C +  C    W    W  CS+ C   G +    + +  +    +KV+    C    
Sbjct: 900 IRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAG-D 958

Query: 463 KPITTIKCADVP 474
           +P     C  VP
Sbjct: 959 RPEARRPCLRVP 970



 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 11/117 (9%)

Query: 11   QFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAP 70
            ++GA +  C KL      + CL+    +       P   C  D     + C+ R P PA 
Sbjct: 918  EWGACSRSCGKLGVQTRGIQCLLP--LSNGTHKVMPAKACAGDRPEARRPCL-RVPCPAQ 974

Query: 71   RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
                W     WS+CS TCG G+  +   C      N+  +C GDR    +VC+   C
Sbjct: 975  ----WR-LGAWSQCSATCGEGIQQRQVVCRT--NANSLGHCEGDRPDTVQVCSLPAC 1024



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 12/88 (13%)

Query: 362 EWTPCSVTCG-VGYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           EW  CS +CG +G   R  +C+    +   +V+    C    P   +  +   R P    
Sbjct: 918 EWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCL---RVPCPAQ 974

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYC 444
           W +GAW+ CS  C   GE + ++R V C
Sbjct: 975 WRLGAWSQCSATC---GEGI-QQRQVVC 998



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/24 (45%), Positives = 14/24 (58%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC 381
           +RL  W+ CS TCG G  +R   C
Sbjct: 975 WRLGAWSQCSATCGEGIQQRQVVC 998


>AL355344-4|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1223

 Score =  242 bits (592), Expect = 2e-63
 Identities = 148/492 (30%), Positives = 221/492 (44%), Gaps = 29/492 (5%)

Query: 7   QCHLQFGA--EAGLCSKLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG+  +  L  +  E C+ LWC   DN   C T   P   GT C P  WC    C
Sbjct: 481 QCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHC 540

Query: 62  VARTPSPA-PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           + ++P     +DGGW  W+++  CSR+CG GV ++SR CNNP P   G  C+G    Y+V
Sbjct: 541 IWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQV 600

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQCVPRDGTDVEM 178
           CN++ CP     FR  QC++ N+          WVPY   D  + CEL C   D  DV  
Sbjct: 601 CNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVF 660

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C  G C  VGCD  V S   +D CGVCGGD + C+TV+G 
Sbjct: 661 MNQVVHDGTRCSYR-DPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGT 719

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLN-GARNATLTEY 297
             K  ++Q+G  ++  IPAG+R+++I+      + I + +  +    LN   + AT   +
Sbjct: 720 LGK-ASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTF 778

Query: 298 FVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL----- 352
              G +     +   E ++ SGPL E I +             + Y+Y + +  L     
Sbjct: 779 TAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGS 838

Query: 353 -------HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQCYHIEPPRHQA 404
                     + + L  W PCS  CG G     Y C  +    +V++  C H + P+   
Sbjct: 839 NNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPK--P 896

Query: 405 LMKQCRKPACVH--WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVI 462
           + ++C +  C    W    W  CS+ C   G +    + +  +    +KV+    C    
Sbjct: 897 IRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAG-D 955

Query: 463 KPITTIKCADVP 474
           +P     C  VP
Sbjct: 956 RPEARRPCLRVP 967



 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 11/117 (9%)

Query: 11   QFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAP 70
            ++GA +  C KL      + CL+    +       P   C  D     + C+ R P PA 
Sbjct: 915  EWGACSRSCGKLGVQTRGIQCLLP--LSNGTHKVMPAKACAGDRPEARRPCL-RVPCPAQ 971

Query: 71   RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
                W     WS+CS TCG G+  +   C      N+  +C GDR    +VC+   C
Sbjct: 972  ----WR-LGAWSQCSATCGEGIQQRQVVCRT--NANSLGHCEGDRPDTVQVCSLPAC 1021



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 12/88 (13%)

Query: 362 EWTPCSVTCG-VGYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           EW  CS +CG +G   R  +C+    +   +V+    C    P   +  +   R P    
Sbjct: 915 EWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCL---RVPCPAQ 971

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYC 444
           W +GAW+ CS  C   GE + ++R V C
Sbjct: 972 WRLGAWSQCSATC---GEGI-QQRQVVC 995



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/24 (45%), Positives = 14/24 (58%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC 381
           +RL  W+ CS TCG G  +R   C
Sbjct: 972 WRLGAWSQCSATCGEGIQQRQVVC 995


>AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.
          Length = 1159

 Score =  241 bits (590), Expect = 4e-63
 Identities = 148/492 (30%), Positives = 221/492 (44%), Gaps = 29/492 (5%)

Query: 7   QCHLQFGA--EAGLCSKLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG+  +  L  +  E C+ LWC   DN   C T   P   GT C P  WC    C
Sbjct: 417 QCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHC 476

Query: 62  VARTPSPA-PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           + ++P     +DGGW  W+++  CSR+CG GV ++SR CNNP P   G  C+G    Y+V
Sbjct: 477 IWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRPCLGPMFEYQV 536

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQCVPRDGTDVEM 178
           CN++ CP     FR  QC++ N+          WVPY   D  + CEL C   D  DV  
Sbjct: 537 CNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVF 596

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C  G C  VGCD  V S   +D CGVCGGD + C+TV+G 
Sbjct: 597 MNQVVHDGTRCSYR-DPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGT 655

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLN-GARNATLTEY 297
             K  ++Q+G  ++  IPAG+R+++I+      + I + +  +    LN   + AT   +
Sbjct: 656 LGK-ASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTF 714

Query: 298 FVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL----- 352
              G +     +   E ++ SGPL E I +             + Y+Y + +  L     
Sbjct: 715 TAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGS 774

Query: 353 -------HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQCYHIEPPRHQA 404
                     + + L  W PCS  CG G     Y C  +    +V++  C H + P+   
Sbjct: 775 NNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPK--P 832

Query: 405 LMKQCRKPACVH--WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVI 462
           + ++C +  C    W    W  CS+ C   G +    + +  +    +KV+    C    
Sbjct: 833 IRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAG-D 891

Query: 463 KPITTIKCADVP 474
           +P     C  VP
Sbjct: 892 RPEARRPCLRVP 903



 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 11/117 (9%)

Query: 11  QFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAP 70
           ++GA +  C KL      + CL+    +       P   C  D     + C+ R P PA 
Sbjct: 851 EWGACSRSCGKLGVQTRGIQCLLP--LSNGTHKVMPAKACAGDRPEARRPCL-RVPCPAQ 907

Query: 71  RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
               W     WS+CS TCG G+  +   C      N+  +C GDR    +VC+   C
Sbjct: 908 ----WR-LGAWSQCSATCGEGIQQRQVVCRT--NANSLGHCEGDRPDTVQVCSLPAC 957



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 12/88 (13%)

Query: 362 EWTPCSVTCG-VGYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           EW  CS +CG +G   R  +C+    +   +V+    C    P   +  +   R P    
Sbjct: 851 EWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCL---RVPCPAQ 907

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYC 444
           W +GAW+ CS  C   GE + ++R V C
Sbjct: 908 WRLGAWSQCSATC---GEGI-QQRQVVC 931



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/24 (45%), Positives = 14/24 (58%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC 381
           +RL  W+ CS TCG G  +R   C
Sbjct: 908 WRLGAWSQCSATCGEGIQQRQVVC 931


>AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and
           metalloprotease with thrombospondin type 1 motif 14 prec
           protein.
          Length = 1223

 Score =  241 bits (590), Expect = 4e-63
 Identities = 148/492 (30%), Positives = 221/492 (44%), Gaps = 29/492 (5%)

Query: 7   QCHLQFGA--EAGLCSKLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG+  +  L  +  E C+ LWC   DN   C T   P   GT C P  WC    C
Sbjct: 481 QCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHC 540

Query: 62  VARTPSPA-PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           + ++P     +DGGW  W+++  CSR+CG GV ++SR CNNP P   G  C+G    Y+V
Sbjct: 541 IWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRPCLGPMFEYQV 600

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQCVPRDGTDVEM 178
           CN++ CP     FR  QC++ N+          WVPY   D  + CEL C   D  DV  
Sbjct: 601 CNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVF 660

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C  G C  VGCD  V S   +D CGVCGGD + C+TV+G 
Sbjct: 661 MNQVVHDGTRCSYR-DPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGT 719

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLN-GARNATLTEY 297
             K  ++Q+G  ++  IPAG+R+++I+      + I + +  +    LN   + AT   +
Sbjct: 720 LGK-ASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTF 778

Query: 298 FVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL----- 352
              G +     +   E ++ SGPL E I +             + Y+Y + +  L     
Sbjct: 779 TAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGS 838

Query: 353 -------HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQCYHIEPPRHQA 404
                     + + L  W PCS  CG G     Y C  +    +V++  C H + P+   
Sbjct: 839 NNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPK--P 896

Query: 405 LMKQCRKPACVH--WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVI 462
           + ++C +  C    W    W  CS+ C   G +    + +  +    +KV+    C    
Sbjct: 897 IRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAG-D 955

Query: 463 KPITTIKCADVP 474
           +P     C  VP
Sbjct: 956 RPEARRPCLRVP 967



 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 11/117 (9%)

Query: 11   QFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAP 70
            ++GA +  C KL      + CL+    +       P   C  D     + C+ R P PA 
Sbjct: 915  EWGACSRSCGKLGVQTRGIQCLLP--LSNGTHKVMPAKACAGDRPEARRPCL-RVPCPAQ 971

Query: 71   RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
                W     WS+CS TCG G+  +   C      N+  +C GDR    +VC+   C
Sbjct: 972  ----WR-LGAWSQCSATCGEGIQQRQVVCRT--NANSLGHCEGDRPDTVQVCSLPAC 1021



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 12/88 (13%)

Query: 362 EWTPCSVTCG-VGYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           EW  CS +CG +G   R  +C+    +   +V+    C    P   +  +   R P    
Sbjct: 915 EWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCL---RVPCPAQ 971

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYC 444
           W +GAW+ CS  C   GE + ++R V C
Sbjct: 972 WRLGAWSQCSATC---GEGI-QQRQVVC 995



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/24 (45%), Positives = 14/24 (58%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC 381
           +RL  W+ CS TCG G  +R   C
Sbjct: 972 WRLGAWSQCSATCGEGIQQRQVVC 995


>AK131344-1|BAD18500.1|  502|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16363 fis, clone THYMU2031139, weakly  similar
           to Homo sapiens zinc metalloprotease ADAMTS7 (ADAMTS7)
           mRNA. ).
          Length = 502

 Score =  239 bits (584), Expect = 2e-62
 Identities = 111/268 (41%), Positives = 145/268 (54%), Gaps = 9/268 (3%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSEL-CEHLWCLV--DNVCTTMMRPAAPGTTCGPDMWCQN 58
           + A  QC + FG  A  C  +  L C  LWCLV  D  C T + P   GT CG D WC+ 
Sbjct: 227 YSANEQCQILFGMNATFCRNMEHLMCAGLWCLVEGDTSCKTKLDPPLDGTECGADKWCRA 286

Query: 59  QTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRY 118
             CV++TP P   DG W PW  WS CSRTCG G   + R+C+NP P   G +C G    +
Sbjct: 287 GECVSKTPIPEHVDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCPGASVEH 346

Query: 119 KVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEM 178
            VC   PCP   PSFR+ QC  H+ +  K + +   V     DKPCEL C P       +
Sbjct: 347 AVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVV--DDKPCELYCSPLGKESPLL 404

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGTPC       D+C+ G C K+GCD I+ S  +ED CGVC GDG  C   +G 
Sbjct: 405 VADRVLDGTPCGPY--ETDLCVHGKCQKIGCDGIIGSAAKEDRCGVCSGDGKTCHLAKGD 462

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQE 266
           ++    R +G+ E A+IPAG+R +++ E
Sbjct: 463 FSH--ARGTGYIEAAVIPAGARRIRVVE 488


>BC089435-1|AAH89435.1|  918|Homo sapiens ADAMTS8 protein protein.
          Length = 918

 Score =  236 bits (577), Expect = 1e-61
 Identities = 144/423 (34%), Positives = 206/423 (48%), Gaps = 46/423 (10%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLS--ELCEHLWCLVDN---VCTTM--MRPAAPGTTCGPD 53
           ++    QC   FG +   C   S  ++C  LWC  D    +C T     P A GT CGP 
Sbjct: 474 LYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKNGSLPWADGTPCGPG 533

Query: 54  MWCQNQTCVARTPSPAPR---DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNY 110
             C   +C+       P+   DGGW PW  W ECSRTCG GV    REC +PEP N G Y
Sbjct: 534 HLCSEGSCLPEEEVERPKPVADGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRY 593

Query: 111 CIGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPY--KNETIDEWVPYFDQDKP---CE 165
           C+G R++Y+ C+T+ CP +  SFRE QC ++N   Y   +  + +WVP +    P   C+
Sbjct: 594 CLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCK 653

Query: 166 LQCVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVC 225
           L C  R  ++ ++    V DGT C     +  +C+ G C K GCD +VDS  + D CGVC
Sbjct: 654 LFCRARGRSEFKVFEAKVIDGTLCGPE--TLAICVRGQCVKAGCDHVVDSPRKLDKCGVC 711

Query: 226 GGDGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSP-----GNYISIGSTK 280
           GG G +C+ V G     T    G++++  IPAG+ N+ ++++  P     GNY+++  T 
Sbjct: 712 GGKGNSCRKVSGSL---TPTNYGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLAL-KTA 767

Query: 281 SRRMFLNG--ARNATLTEYFVAGAQAIYERD-RDWEKVRISGPLAEDIKVYQRIFRGRHR 337
             +  LNG  A +A   +  V G    Y       E+++   PL E + V      G   
Sbjct: 768 DGQYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLLTVPGEVF 827

Query: 338 NPGVTYQYTV----------DKQRLHKK------HS-YRLSEWTPCSVTCGVGYTRRYYE 380
            P V Y + V           K+R          H+ + L +W+ CS TCG G+ RR  E
Sbjct: 828 PPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVE 887

Query: 381 CID 383
           C D
Sbjct: 888 CRD 890



 Score = 37.1 bits (82), Expect = 0.13
 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 3/51 (5%)

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNG--NYCIGDRSRYKVCNTDPCPI 128
           +WSECS TCGAG   ++ EC +P    +   N  +      K C +  CP+
Sbjct: 869 DWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDA-KPCESQLCPL 918


>AF060153-1|AAD48081.1|  890|Homo sapiens METH2 protein protein.
          Length = 890

 Score =  236 bits (577), Expect = 1e-61
 Identities = 144/423 (34%), Positives = 206/423 (48%), Gaps = 46/423 (10%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLS--ELCEHLWCLVDN---VCTTM--MRPAAPGTTCGPD 53
           ++    QC   FG +   C   S  ++C  LWC  D    +C T     P A GT CGP 
Sbjct: 446 LYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKNGSLPWADGTPCGPG 505

Query: 54  MWCQNQTCVARTPSPAPR---DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNY 110
             C   +C+       P+   DGGW PW  W ECSRTCG GV    REC +PEP N G Y
Sbjct: 506 HLCSEGSCLPEEEVERPKPVVDGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRY 565

Query: 111 CIGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPY--KNETIDEWVPYFDQDKP---CE 165
           C+G R++Y+ C+T+ CP +  SFRE QC ++N   Y   +  + +WVP +    P   C+
Sbjct: 566 CLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCK 625

Query: 166 LQCVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVC 225
           L C  R  ++ ++    V DGT C     +  +C+ G C K GCD +VDS  + D CGVC
Sbjct: 626 LFCRARGRSEFKVFEAKVIDGTLCGPE--TLAICVRGQCVKAGCDHVVDSPRKLDKCGVC 683

Query: 226 GGDGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSP-----GNYISIGSTK 280
           GG G +C+ V G     T    G++++  IPAG+ N+ ++++  P     GNY+++  T 
Sbjct: 684 GGKGNSCRKVSGSL---TPTNYGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLAL-KTA 739

Query: 281 SRRMFLNG--ARNATLTEYFVAGAQAIYERD-RDWEKVRISGPLAEDIKVYQRIFRGRHR 337
             +  LNG  A +A   +  V G    Y       E+++   PL E + V      G   
Sbjct: 740 DGQYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLLTVPGEVF 799

Query: 338 NPGVTYQYTV----------DKQRLHKK------HS-YRLSEWTPCSVTCGVGYTRRYYE 380
            P V Y + V           K+R          H+ + L +W+ CS TCG G+ RR  E
Sbjct: 800 PPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVE 859

Query: 381 CID 383
           C D
Sbjct: 860 CRD 862



 Score = 37.1 bits (82), Expect = 0.13
 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 3/51 (5%)

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNG--NYCIGDRSRYKVCNTDPCPI 128
           +WSECS TCGAG   ++ EC +P    +   N  +      K C +  CP+
Sbjct: 841 DWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDA-KPCESQLCPL 890


>AJ345098-1|CAC87943.1| 1223|Homo sapiens
           metalloprotease-disintegrin protease protein.
          Length = 1223

 Score =  234 bits (572), Expect = 6e-61
 Identities = 148/493 (30%), Positives = 218/493 (44%), Gaps = 31/493 (6%)

Query: 7   QCHLQFGA--EAGLCSKLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG+  +  L  +  E C+ LWC   DN   C T   P   GT C P  WC    C
Sbjct: 481 QCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHC 540

Query: 62  VARTPSPA-PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           + ++P     +DGGW  W+++  CSR+CG GV ++SR CNNP P   G  C+G    Y+V
Sbjct: 541 IWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRPCLGPMFEYQV 600

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQCVPRDGTDVEM 178
           CN++ CP     FR  QC++ N+          WVPY   D  + CEL C   D  DV  
Sbjct: 601 CNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVF 660

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C  G C  VGCD  V S   +D CGVCGGD + C+TV+G 
Sbjct: 661 MNQVVHDGTRCSYR-DPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGT 719

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLN-GARNATLTEY 297
             K  ++Q+G  ++  IPAG+R+++I+      + I + +  +    LN   + AT   +
Sbjct: 720 LGK-ASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTF 778

Query: 298 FVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL----- 352
              G +     +   E ++ SGPL E I +             + Y+Y + +  L     
Sbjct: 779 TAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGS 838

Query: 353 -------HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQCYHIEPP---R 401
                     + + L  W PCS  CG G     Y C  +    +V +  C H + P   R
Sbjct: 839 NNVLLEEMDTYEWALKSWAPCSKACGGGIRFTKYGCRRRRDHHMVHRHLCDHKKRPKPIR 898

Query: 402 HQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQV 461
            ++    C +P    W    W  CS+     G +    + +  +    +KV+    C   
Sbjct: 899 RRSNQHPCSQPV---WVTEEWGACSRSYGKLGVQTRGIQCLLPLSNGTHKVMPAKACAG- 954

Query: 462 IKPITTIKCADVP 474
            +P     C  VP
Sbjct: 955 DRPEARRPCLRVP 967



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 9/82 (10%)

Query: 46   PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
            P   C  D     + C+ R P PA     W     WS+CS TCG G+  +   C      
Sbjct: 948  PAKACAGDRPEARRPCL-RVPCPAQ----WR-LGAWSQCSATCGEGIQQRQVVCRT--NA 999

Query: 106  NNGNYCIGDR-SRYKVCNTDPC 126
            N+  +C GDR    +VC+   C
Sbjct: 1000 NSLGHCEGDRPDTVQVCSLPAC 1021



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 12/88 (13%)

Query: 362 EWTPCSVTCG-VGYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           EW  CS + G +G   R  +C+    +   +V+    C    P   +  +   R P    
Sbjct: 915 EWGACSRSYGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCL---RVPCPAQ 971

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYC 444
           W +GAW+ CS  C   GE + ++R V C
Sbjct: 972 WRLGAWSQCSATC---GEGI-QQRQVVC 995



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/24 (45%), Positives = 14/24 (58%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC 381
           +RL  W+ CS TCG G  +R   C
Sbjct: 972 WRLGAWSQCSATCGEGIQQRQVVC 995


>BC113874-1|AAI13875.1|  676|Homo sapiens ADAMTS8 protein protein.
          Length = 676

 Score =  231 bits (565), Expect = 4e-60
 Identities = 143/423 (33%), Positives = 205/423 (48%), Gaps = 46/423 (10%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLS--ELCEHLWCLVDN---VCTTM--MRPAAPGTTCGPD 53
           ++    QC   FG +   C   S  ++C  LWC  D    +C T     P A GT CGP 
Sbjct: 232 LYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKNGSLPWADGTPCGPG 291

Query: 54  MWCQNQTCVARTPSPAPR---DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNY 110
             C   +C+       P+   DGGW PW  W ECSRTCG GV    REC +PEP N G Y
Sbjct: 292 HLCSEGSCLPEEEVERPKPVVDGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRY 351

Query: 111 CIGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPY--KNETIDEWVPYFDQDKP---CE 165
           C+G R++Y+ C+T+ CP +  SFRE QC ++N   Y   +  + +WVP +    P   C+
Sbjct: 352 CLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCK 411

Query: 166 LQCVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVC 225
           L C  R  ++ ++    V DGT C     +  +C+ G C K GCD +VDS  + D CGV 
Sbjct: 412 LFCRARGRSEFKVFEAKVIDGTLCGPE--TLAICVRGQCVKAGCDHVVDSPRKLDKCGVR 469

Query: 226 GGDGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSP-----GNYISIGSTK 280
           GG G +C+ V G     T    G++++  IPAG+ N+ ++++  P     GNY+++  T 
Sbjct: 470 GGKGNSCRKVSGSL---TPTNYGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLAL-KTA 525

Query: 281 SRRMFLNG--ARNATLTEYFVAGAQAIYERD-RDWEKVRISGPLAEDIKVYQRIFRGRHR 337
             +  LNG  A +A   +  V G    Y       E+++   PL E + V      G   
Sbjct: 526 DGQYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLLAVPGEVF 585

Query: 338 NPGVTYQYTV----------DKQRLHKK------HS-YRLSEWTPCSVTCGVGYTRRYYE 380
            P V Y + V           K+R          H+ + L +W+ CS TCG G+ RR  E
Sbjct: 586 PPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVE 645

Query: 381 CID 383
           C D
Sbjct: 646 CRD 648



 Score = 37.1 bits (82), Expect = 0.13
 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 3/51 (5%)

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNG--NYCIGDRSRYKVCNTDPCPI 128
           +WSECS TCGAG   ++ EC +P    +   N  +      K C +  CP+
Sbjct: 627 DWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDA-KPCESQLCPL 676


>AB209717-1|BAD92954.1|  418|Homo sapiens ADAMTS-8 precursor variant
           protein.
          Length = 418

 Score =  229 bits (559), Expect = 2e-59
 Identities = 138/396 (34%), Positives = 195/396 (49%), Gaps = 44/396 (11%)

Query: 26  CEHLWCLVDN---VCTTM--MRPAAPGTTCGPDMWCQNQTCVARTPSPAPR---DGGWGP 77
           C  LWC  D    +C T     P A GT CGP   C   +C+       P+   DGGW P
Sbjct: 1   CAQLWCHTDGAEPLCHTKNGSLPWADGTPCGPGHLCSEGSCLPEEEVERPKPVVDGGWAP 60

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQ 137
           W  W ECSRTCG GV    REC +PEP N G YC+G R++Y+ C+T+ CP +  SFRE Q
Sbjct: 61  WGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDGKSFREQQ 120

Query: 138 CSRHNNMPY--KNETIDEWVPYFDQDKP---CELQCVPRDGTDVEMLGGFVADGTPCRQA 192
           C ++N   Y   +  + +WVP +    P   C+L C  R  ++ ++    V DGT C   
Sbjct: 121 CEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPE 180

Query: 193 IGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTRQSGFSEV 252
             +  +C+ G C K GCD +VDS  + D CGVCGG G +C+ V G     T    G++++
Sbjct: 181 --TLAICVRGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSL---TPTNYGYNDI 235

Query: 253 AIIPAGSRNVKIQEKVSP-----GNYISIGSTKSRRMFLNG--ARNATLTEYFVAGAQAI 305
             IPAG+ N+ ++++  P     GNY+++  T   +  LNG  A +A   +  V G    
Sbjct: 236 VTIPAGATNIDVKQRSHPGVQNDGNYLAL-KTADGQYLLNGNLAISAIEQDILVKGTILK 294

Query: 306 YERD-RDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTV----------DKQRLHK 354
           Y       E+++   PL E + V      G    P V Y + V           K+R   
Sbjct: 295 YSGSIATLERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATT 354

Query: 355 K------HS-YRLSEWTPCSVTCGVGYTRRYYECID 383
                  H+ + L +W+ CS TCG G+ RR  EC D
Sbjct: 355 NIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVECRD 390



 Score = 37.5 bits (83), Expect = 0.10
 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 3/51 (5%)

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNG--NYCIGDRSRYKVCNTDPCPI 128
           +WSECS TCGAG   ++ EC +P    +   N  +      K C +  CP+
Sbjct: 369 DWSECSSTCGAGWQRRTVECRDPSSQASATCNKALKPEDA-KPCESQLCPL 418


>AP001697-2|BAA95503.1|  517|Homo sapiens disintegrin-like and
           metalloprotease with thrombospondin type 1 motif, 5
           protein.
          Length = 517

 Score =  214 bits (522), Expect = 7e-55
 Identities = 135/447 (30%), Positives = 201/447 (44%), Gaps = 46/447 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLV----DNVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC+L FG E  +C  + ++C  LWC V      VC T   PA  GT CG    C 
Sbjct: 78  YDATQQCNLTFGPEYSVCPGM-DVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICL 136

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              CV +T          G WG W  W +CSR+CG GV    R CNNP P NNG YC G 
Sbjct: 137 QGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGK 196

Query: 115 RSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKN---ETIDEWVPYFDQDKP---CELQC 168
           R+ Y+ C+  PCP N  SFR  QC   N         +T  EWVP +    P   C+L C
Sbjct: 197 RAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTC 256

Query: 169 VPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGD 228
             +      +    V DGT CR  + S  +C+ G C + GCD I+ S ++ D CGVCGGD
Sbjct: 257 RAKGTGYYVVFSPKVTDGTECR--LYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGD 314

Query: 229 GTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN-----YISIGSTKSRR 283
            ++C  + G + K   +  G+++V  IP G+ ++K+++  +        Y+++   K+  
Sbjct: 315 NSSCTKIVGTFNK---KSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLAL-KKKNGE 370

Query: 284 MFLNGARNATLTEYF--VAGAQAIYE--RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
             +NG    + +E    + G    Y     RD     +     ++I + Q +     +  
Sbjct: 371 YLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPL 430

Query: 340 GVTYQYTVDKQRLHKKHS-----------------YRLSEWTPCSVTCGVGYTRRYYECI 382
            V Y + V K+   K +S                 +    W  CS TC  G+  R  +C 
Sbjct: 431 DVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQ 490

Query: 383 DQHQRVVEQSQCYHIEPPRHQALMKQC 409
           D ++++ +            Q L+K+C
Sbjct: 491 DGNRKLAKGCPLSQRPSAFKQCLLKKC 517


>BC093777-1|AAH93777.1|  930|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
          Length = 930

 Score =  213 bits (520), Expect = 1e-54
 Identities = 135/447 (30%), Positives = 200/447 (44%), Gaps = 46/447 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLV----DNVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC+L FG E  +C  + ++C  LWC V      VC T   PA  GT CG    C 
Sbjct: 491 YDATQQCNLTFGPEYSVCPGM-DVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICL 549

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              CV +T          G WG W  W +CSR+CG GV    R CNNP P NNG YC G 
Sbjct: 550 QGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGK 609

Query: 115 RSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKN---ETIDEWVPYFDQDKP---CELQC 168
           R+ Y+ C+  PCP N  SFR  QC   N         +T  EWVP +    P   C+L C
Sbjct: 610 RAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTC 669

Query: 169 VPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGD 228
             +      +    V DGT CR    S  +C+ G C + GCD I+ S ++ D CGVCGGD
Sbjct: 670 RAKGTGYYVVFSPKVTDGTECRPY--SNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGD 727

Query: 229 GTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN-----YISIGSTKSRR 283
            ++C  + G + K   +  G+++V  IP G+ ++K+++  +        Y+++   K+  
Sbjct: 728 NSSCTKIVGTFNK---KSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLAL-KKKNGE 783

Query: 284 MFLNGARNATLTEYF--VAGAQAIYE--RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
             +NG    + +E    + G    Y     RD     +     ++I + Q +     +  
Sbjct: 784 YLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPL 843

Query: 340 GVTYQYTVDKQRLHKKHS-----------------YRLSEWTPCSVTCGVGYTRRYYECI 382
            V Y + V K+   K +S                 +    W  CS TC  G+  R  +C 
Sbjct: 844 DVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQ 903

Query: 383 DQHQRVVEQSQCYHIEPPRHQALMKQC 409
           D ++++ +            Q L+K+C
Sbjct: 904 DGNRKLAKGCPLSQRPSAFKQCLLKKC 930


>BC093775-1|AAH93775.1|  930|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
          Length = 930

 Score =  213 bits (520), Expect = 1e-54
 Identities = 135/447 (30%), Positives = 200/447 (44%), Gaps = 46/447 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLV----DNVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC+L FG E  +C  + ++C  LWC V      VC T   PA  GT CG    C 
Sbjct: 491 YDATQQCNLTFGPEYSVCPGM-DVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICL 549

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              CV +T          G WG W  W +CSR+CG GV    R CNNP P NNG YC G 
Sbjct: 550 QGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGK 609

Query: 115 RSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKN---ETIDEWVPYFDQDKP---CELQC 168
           R+ Y+ C+  PCP N  SFR  QC   N         +T  EWVP +    P   C+L C
Sbjct: 610 RAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTC 669

Query: 169 VPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGD 228
             +      +    V DGT CR    S  +C+ G C + GCD I+ S ++ D CGVCGGD
Sbjct: 670 RAKGTGYYVVFSPKVTDGTECRPY--SNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGD 727

Query: 229 GTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN-----YISIGSTKSRR 283
            ++C  + G + K   +  G+++V  IP G+ ++K+++  +        Y+++   K+  
Sbjct: 728 NSSCTKIVGTFNK---KSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLAL-KKKNGE 783

Query: 284 MFLNGARNATLTEYF--VAGAQAIYE--RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
             +NG    + +E    + G    Y     RD     +     ++I + Q +     +  
Sbjct: 784 YLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPL 843

Query: 340 GVTYQYTVDKQRLHKKHS-----------------YRLSEWTPCSVTCGVGYTRRYYECI 382
            V Y + V K+   K +S                 +    W  CS TC  G+  R  +C 
Sbjct: 844 DVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQ 903

Query: 383 DQHQRVVEQSQCYHIEPPRHQALMKQC 409
           D ++++ +            Q L+K+C
Sbjct: 904 DGNRKLAKGCPLSQRPSAFKQCLLKKC 930


>AF142099-1|AAD49577.1|  930|Homo sapiens aggrecanase-2 protein.
          Length = 930

 Score =  213 bits (520), Expect = 1e-54
 Identities = 135/447 (30%), Positives = 200/447 (44%), Gaps = 46/447 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLV----DNVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC+L FG E  +C  + ++C  LWC V      VC T   PA  GT CG    C 
Sbjct: 491 YDATQQCNLTFGPEYSVCPGM-DVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICL 549

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              CV +T          G WG W  W +CSR+CG GV    R CNNP P NNG YC G 
Sbjct: 550 QGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGK 609

Query: 115 RSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKN---ETIDEWVPYFDQDKP---CELQC 168
           R+ Y+ C+  PCP N  SFR  QC   N         +T  EWVP +    P   C+L C
Sbjct: 610 RAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTC 669

Query: 169 VPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGD 228
             +      +    V DGT CR    S  +C+ G C + GCD I+ S ++ D CGVCGGD
Sbjct: 670 RAKGTGYYVVFSPKVTDGTECRPY--SNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGD 727

Query: 229 GTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN-----YISIGSTKSRR 283
            ++C  + G + K   +  G+++V  IP G+ ++K+++  +        Y+++   K+  
Sbjct: 728 NSSCTKIVGTFNK---KSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLAL-KKKNGE 783

Query: 284 MFLNGARNATLTEYF--VAGAQAIYE--RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
             +NG    + +E    + G    Y     RD     +     ++I + Q +     +  
Sbjct: 784 YLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPL 843

Query: 340 GVTYQYTVDKQRLHKKHS-----------------YRLSEWTPCSVTCGVGYTRRYYECI 382
            V Y + V K+   K +S                 +    W  CS TC  G+  R  +C 
Sbjct: 844 DVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQ 903

Query: 383 DQHQRVVEQSQCYHIEPPRHQALMKQC 409
           D ++++ +            Q L+K+C
Sbjct: 904 DGNRKLAKGCPLSQRPSAFKQCLLKKC 930


>AF141293-1|AAF02493.1|  518|Homo sapiens ADAMTS5 protein protein.
          Length = 518

 Score =  211 bits (515), Expect = 5e-54
 Identities = 135/447 (30%), Positives = 198/447 (44%), Gaps = 46/447 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLV----DNVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC+L FG E  +C    ++C  LWC V      VC T   PA  GT CG    C 
Sbjct: 79  YDATQQCNLTFGPEYSVCPG-XDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICL 137

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              CV +T          G WG W  W +CSR+CG GV    R CNNP P NNG YC G 
Sbjct: 138 QGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGK 197

Query: 115 RSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKN---ETIDEWVPYFDQDKP---CELQC 168
           R+ Y  C+  PCP N  SFR  QC   N         +T  EWVP +    P   C+L C
Sbjct: 198 RAIYHSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTC 257

Query: 169 VPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGD 228
             +      +    V DGT CR    S  +C+ G C + GCD I+ S ++ D CGVCGGD
Sbjct: 258 RAKGTGYYVVFSPKVTDGTECRPY--SNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGD 315

Query: 229 GTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN-----YISIGSTKSRR 283
            ++C  + G + K   +  G+++V  IP G+ ++K+++  +        Y+++   K+  
Sbjct: 316 NSSCTKIVGTFNK---KSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLAL-KKKNGE 371

Query: 284 MFLNGARNATLTEYF--VAGAQAIYE--RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNP 339
             +NG    + +E    + G    Y     RD     +     ++I + Q +     +  
Sbjct: 372 YLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPL 431

Query: 340 GVTYQYTVDKQRLHKKHS-----------------YRLSEWTPCSVTCGVGYTRRYYECI 382
            V Y + V K+   K +S                 +    W  CS TC  G+  R  +C 
Sbjct: 432 DVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQ 491

Query: 383 DQHQRVVEQSQCYHIEPPRHQALMKQC 409
           D ++++ +            Q L+K+C
Sbjct: 492 DGNRKLAKGCPLSQRPSAFKQCLLKKC 518


>AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein
           protein.
          Length = 1235

 Score =  208 bits (509), Expect = 2e-53
 Identities = 127/432 (29%), Positives = 199/432 (46%), Gaps = 44/432 (10%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFR 134
           WGPWS+WS CSRTCG GVS + R C +    + G+ C+G    ++ C T+ CP     FR
Sbjct: 29  WGPWSQWSPCSRTCGGGVSFRERPCYSQRR-DGGSSCVGPARSHRSCRTESCPDGARDFR 87

Query: 135 EVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEMLGGFVADGTPCRQAIG 194
             QC+  +   ++      W+PY+     CEL C+P+           V DGTPC    G
Sbjct: 88  AEQCAEFDGAEFQGRRY-RWLPYYSAPNKCELNCIPKGENFYYKHREAVVDGTPCEP--G 144

Query: 195 SRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTRQSGFSEVAI 254
            RD+C+ G C  VGCD  +DS  +ED C  CGGDGT C  V G +      + G++++ I
Sbjct: 145 KRDVCVDGSCRVVGCDHELDSSKQEDKCLRCGGDGTTCYPVAGTFDANDLSR-GYNQILI 203

Query: 255 IPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYFVAGAQAI-YER----D 309
           +P G+ ++ I E  +  N++++ + +    +LNG           A +  + YER    D
Sbjct: 204 VPMGATSILIDEAAASRNFLAVKNVRG-EYYLNGHWTIEAARALPAASTILHYERGAEGD 262

Query: 310 RDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVT 369
              E++   GP +E + V + I   +  NPGV Y+Y +  +R     S+    W+ CS  
Sbjct: 263 LAPERLHARGPTSEPL-VIELI--SQEPNPGVHYEYHLPLRRPSPGFSWSHGSWSDCSAE 319

Query: 370 CGVGYTRRYYECIDQHQRVVEQSQCYHIEPP--RHQALMKQC---RKPACVH-------- 416
           CG G+  R   C   H+   +   C     P  R    +  C   ++ + +H        
Sbjct: 320 CGGGHQSRLVFCTIDHEAYPDH-MCQRQPRPADRRSCNLHPCPETKRTSYLHRPGAWRLA 378

Query: 417 ---------WWVGAWNPCSKLCHMPGEEVTKERSVYCVDK---VMNKVVDDSECGQVIKP 464
                    W  G W PCS  C       ++ RSVYC+      + + V+++EC  +   
Sbjct: 379 GAQRVCGNSWKAGPWAPCSASC----GGGSQSRSVYCISSDGAGIQEAVEEAECAGLPGK 434

Query: 465 ITTIKCADVPAC 476
              I+  ++  C
Sbjct: 435 PPAIQACNLQRC 446



 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 37/121 (30%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQH----QRVVEQSQCYHI--EPPRHQALMKQC 409
           +S++   W PCS +CG G   R   CI       Q  VE+++C  +  +PP  QA    C
Sbjct: 386 NSWKAGPWAPCSASCGGGSQSRSVYCISSDGAGIQEAVEEAECAGLPGKPPAIQA----C 441

Query: 410 RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIK 469
               C  W    W  CS  C   G  V K RSV C  +    ++  + C    +P  T  
Sbjct: 442 NLQRCAAWSPEPWGECSVSC---GVGVRK-RSVTCRGE-RGSLLHTAACSLEDRPPLTEP 496

Query: 470 C 470
           C
Sbjct: 497 C 497



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/116 (29%), Positives = 47/116 (40%), Gaps = 14/116 (12%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC-YHIEPPRHQALMKQ-CRKPACVHWWVG 420
           W  CSV+CGVG  +R   C  +   ++  + C     PP  +  + + C   +   W VG
Sbjct: 454 WGECSVSCGVGVRKRSVTCRGERGSLLHTAACSLEDRPPLTEPCVHEDCPLLSDQAWHVG 513

Query: 421 AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECG--QVIKPITTIKCADVP 474
            W  CSK C       T+ R V C       +   S CG  Q  KP+    C   P
Sbjct: 514 TWGLCSKSC----SSGTRRRQVICA------IGPPSHCGSLQHSKPVDVEPCNTQP 559



 Score = 31.5 bits (68), Expect = 6.7
 Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 1/29 (3%)

Query: 71  RDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           R   W P   W ECS +CG GV  +S  C
Sbjct: 445 RCAAWSP-EPWGECSVSCGVGVRKRSVTC 472


>AK128469-1|BAC87455.1|  327|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46613 fis, clone TKIDN2011160, moderately
           similar to ADAM-TS 3 precursor (EC 3.4.24.-). ).
          Length = 327

 Score =  208 bits (507), Expect = 4e-53
 Identities = 103/267 (38%), Positives = 141/267 (52%), Gaps = 10/267 (3%)

Query: 7   QCHLQFGA--EAGLCSKLSELCEHLWCL-VDN--VCTTMMRPAAPGTTCGPDMWCQNQTC 61
           QC   FG+  +  L  +  E C+ LWC   DN   C T   P   GT C P  WC    C
Sbjct: 4   QCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHC 63

Query: 62  VARTPSPA-PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           + ++P     +DGGW  W+++  CSR+CG GV ++SR CNNP P   G  C+G    Y+V
Sbjct: 64  IWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQV 123

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQCVPRDGTDVEM 178
           CN++ CP     FR  QC++ N+          WVPY   D  + CEL C   D  DV  
Sbjct: 124 CNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVF 183

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           +   V DGT C        +C  G C  VGCD  V S   +D CGVCGGD + C+TV+G 
Sbjct: 184 MNQVVHDGTRCSYR-DPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGT 242

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQ 265
             K  ++Q+G  ++  IPAG+R+++I+
Sbjct: 243 LGK-ASKQAGALKLVQIPAGARHIQIE 268


>BC030262-1|AAH30262.1|  439|Homo sapiens ADAMTS-like 1 protein.
          Length = 439

 Score =  206 bits (503), Expect = 1e-52
 Identities = 130/386 (33%), Positives = 188/386 (48%), Gaps = 29/386 (7%)

Query: 67  SPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           S   RDG W  W  WSECSRTCG G S   R C + +       C G   RY+ C+   C
Sbjct: 28  SEEDRDGLWDAWGPWSECSRTCGGGASYSLRRCLSSKS------CEGRNIRYRTCSNVDC 81

Query: 127 PINEPSFREVQCSRHNNMPYKNETIDEWVPYF-DQDKPCELQCVPRDGTDVEMLGGFVAD 185
           P     FR  QCS HN++ +  +   EW+P   D D PC L+C  +  T V  L   V D
Sbjct: 82  PPEAGDFRAQQCSAHNDVKHHGQFY-EWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLD 140

Query: 186 GTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTR 245
           GT C     S DMCISG+C  VGCD  + S V+ED CGVC GDG+ C+ V+G Y    + 
Sbjct: 141 GTRCYTE--SLDMCISGLCQIVGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSA 198

Query: 246 QSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYFVAGAQAI 305
                 V  IP GSR++++  K     Y+   + +  +    G  + + T  F+    ++
Sbjct: 199 TKSDDTVVAIPYGSRHIRLVLKGPDHLYLETKTLQGTK----GENSLSSTGTFLVDNSSV 254

Query: 306 -YERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHSYRLSEWT 364
            +++  D E +R++GPL  D  V  R       +   T Q+   +  +H+   +R +++ 
Sbjct: 255 DFQKFPDKEILRMAGPLTADFIVKIR----NSGSADSTVQFIFYQPIIHR---WRETDFF 307

Query: 365 PCSVTCGVGYTRRYYECID-QHQRVVEQSQC-YHIEPPRHQALMKQCRKPAC-VHWWVGA 421
           PCS TCG GY     EC D +  RVV    C Y+ E  + +  +++C    C   W    
Sbjct: 308 PCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPARWEATP 367

Query: 422 WNPCSKLCHMPGEEVTKERSVYCVDK 447
           W  CS  C   G  + + R+V CV++
Sbjct: 368 WTACSSSC---GGGI-QSRAVSCVEE 389


>AY358886-1|AAQ89245.1|  837|Homo sapiens ADAMTS4 protein.
          Length = 837

 Score =  203 bits (496), Expect = 9e-52
 Identities = 106/285 (37%), Positives = 148/285 (51%), Gaps = 19/285 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVD----NVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC L FG ++  C +L   C  LWC        +C T   P A GT CGP   C 
Sbjct: 443 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGPAQACM 502

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              C+          P+ GGWGPW  W +CSRTCG GV   SR+C  P P N G YC G 
Sbjct: 503 GGRCLHMDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGR 562

Query: 115 RSRYKVCNTDPCPINEP-SFREVQCSRHNNMPYKNETID---EWVPYFDQDKP---CELQ 167
           R+R++ CNT+ CP     +FRE QC+ +N+     ++     +WVP +    P   C+L 
Sbjct: 563 RTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPQDQCKLT 622

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  R      +L   V DGTPC  +  S  +C+ G C   GCD I+ S  + D C VCGG
Sbjct: 623 CQARALGYYYVLEPRVVDGTPC--SPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGG 680

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN 272
           DG+ C    G + K    + G++ V  IPAG+ ++ ++++ +PG+
Sbjct: 681 DGSGCSKQSGSFRK---FRYGYNNVVTIPAGATHILVRQQGNPGH 722


>AF148213-1|AAD41494.1|  837|Homo sapiens aggrecanase-1 protein.
          Length = 837

 Score =  203 bits (496), Expect = 9e-52
 Identities = 106/285 (37%), Positives = 148/285 (51%), Gaps = 19/285 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVD----NVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC L FG ++  C +L   C  LWC        +C T   P A GT CGP   C 
Sbjct: 443 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGPAQACM 502

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              C+          P+ GGWGPW  W +CSRTCG GV   SR+C  P P N G YC G 
Sbjct: 503 GGRCLHMDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGR 562

Query: 115 RSRYKVCNTDPCPINEP-SFREVQCSRHNNMPYKNETID---EWVPYFDQDKP---CELQ 167
           R+R++ CNT+ CP     +FRE QC+ +N+     ++     +WVP +    P   C+L 
Sbjct: 563 RTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPQDQCKLT 622

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  R      +L   V DGTPC  +  S  +C+ G C   GCD I+ S  + D C VCGG
Sbjct: 623 CQARALGYYYVLEPRVVDGTPC--SPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGG 680

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN 272
           DG+ C    G + K    + G++ V  IPAG+ ++ ++++ +PG+
Sbjct: 681 DGSGCSKQSGSFRK---FRYGYNNVVTIPAGATHILVRQQGNPGH 722


>AB014588-1|BAA31663.2|  849|Homo sapiens KIAA0688 protein protein.
          Length = 849

 Score =  203 bits (496), Expect = 9e-52
 Identities = 106/285 (37%), Positives = 148/285 (51%), Gaps = 19/285 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVD----NVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC L FG ++  C +L   C  LWC        +C T   P A GT CGP   C 
Sbjct: 455 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGPAQACM 514

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              C+          P+ GGWGPW  W +CSRTCG GV   SR+C  P P N G YC G 
Sbjct: 515 GGRCLHMDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGR 574

Query: 115 RSRYKVCNTDPCPINEP-SFREVQCSRHNNMPYKNETID---EWVPYFDQDKP---CELQ 167
           R+R++ CNT+ CP     +FRE QC+ +N+     ++     +WVP +    P   C+L 
Sbjct: 575 RTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPQDQCKLT 634

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  R      +L   V DGTPC  +  S  +C+ G C   GCD I+ S  + D C VCGG
Sbjct: 635 CQARALGYYYVLEPRVVDGTPC--SPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGG 692

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN 272
           DG+ C    G + K    + G++ V  IPAG+ ++ ++++ +PG+
Sbjct: 693 DGSGCSKQSGSFRK---FRYGYNNVVTIPAGATHILVRQQGNPGH 734


>AL590714-6|CAH72146.1|  837|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 837

 Score =  202 bits (492), Expect = 3e-51
 Identities = 105/285 (36%), Positives = 148/285 (51%), Gaps = 19/285 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVD----NVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC L FG ++  C +L   C  LWC        +C T   P A GT CGP   C 
Sbjct: 443 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGPAQACM 502

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              C+          P+ GGWGPW  W +CSRTCG GV   SR+C  P P N G YC G 
Sbjct: 503 GGRCLHMDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGR 562

Query: 115 RSRYKVCNTDPCPINEP-SFREVQCSRHNNMPYKNETID---EWVPYFDQDKP---CELQ 167
           R+R++ CNT+ CP     +FRE QC+ +N+     ++     +WVP +    P   C+L 
Sbjct: 563 RTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPQDQCKLT 622

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  +      +L   V DGTPC  +  S  +C+ G C   GCD I+ S  + D C VCGG
Sbjct: 623 CQAQALGYYYVLEPRVVDGTPC--SPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGG 680

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN 272
           DG+ C    G + K    + G++ V  IPAG+ ++ ++++ +PG+
Sbjct: 681 DGSGCSKQSGSFRK---FRYGYNNVVTIPAGATHILVRQQGNPGH 722


>BC109114-1|AAI09115.1|  950|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 15 protein.
          Length = 950

 Score =  201 bits (490), Expect = 5e-51
 Identities = 150/492 (30%), Positives = 215/492 (43%), Gaps = 62/492 (12%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLV----DNVCTTMMRPAAPGTTCGPDMWCQ 57
           +  + QC L FG  +  C  + + C  LWC        VC T   P A GT+CG    C 
Sbjct: 442 YTLSQQCELAFGVGSKPCPYM-QYCTKLWCTGKAKGQMVCQTRHFPWADGTSCGEGKLCL 500

Query: 58  NQTCVARTPSPAPR-DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
              CV R      R DG W  W  +  CSRTCG GV    R+C NP P N G YC G R 
Sbjct: 501 KGACVERHNLNKHRVDGSWAKWDPYGPCSRTCGGGVQLARRQCTNPTPANGGKYCEGVRV 560

Query: 117 RYKVCNTDPCP--INEPSFREVQCSRHNNMPYKNETID---EWVPYFDQDKP---CELQC 168
           +Y+ CN +PCP   +  SFRE QC   N   +    +     WVP +    P   C+L C
Sbjct: 561 KYRSCNLEPCPSSASGKSFREEQCEAFNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLIC 620

Query: 169 VPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGD 228
                    +L   V DGT C  +  S  +C+ G C K GCD  + S    D CGVCGGD
Sbjct: 621 RANGTGYFYVLAPKVVDGTLC--SPDSTSVCVQGKCIKAGCDGNLGSKKRFDKCGVCGGD 678

Query: 229 GTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEK-----VSPGNYISIGSTKSRR 283
             +CK V G++TK      G++ V  IPAG+ ++ I+++     +   NY+++ +++ + 
Sbjct: 679 NKSCKKVTGLFTK---PMHGYNFVVAIPAGASSIDIRQRGYKGLIGDDNYLALKNSQGKY 735

Query: 284 MFLNG--ARNATLTEYFVAGAQAIYE-RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPG 340
           + LNG    +A   +  V G+   Y       E ++ S P+ E + V + +  G+   P 
Sbjct: 736 L-LNGHFVVSAVERDLVVKGSLLRYSGTGTAVESLQASRPILEPLTV-EVLSVGKMTPPR 793

Query: 341 VTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPP 400
           V Y + + K+    K S+      P  +                H  V+  S    +E P
Sbjct: 794 VRYSFYLPKEPREDKSSHPKDPRGPSVL----------------HNSVLSLSN--QVEQP 835

Query: 401 RHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQ 460
                    R PA   W  G+W PCS  C   G  + K R+V C      + V    C  
Sbjct: 836 -------DDRPPA--RWVAGSWGPCSASC---GSGLQK-RAVDCRGSAGQRTV--PACDA 880

Query: 461 VIKPITTIKCAD 472
             +P+ T  C +
Sbjct: 881 AHRPVETQACGE 892



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 7/68 (10%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGA 421
           W PCS +CG G  +R  +C     QR V      H  P   QA    C +P C  W + A
Sbjct: 848 WGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAH-RPVETQA----CGEP-CPTWELSA 901

Query: 422 WNPCSKLC 429
           W+PCSK C
Sbjct: 902 WSPCSKSC 909



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 1/44 (2%)

Query: 357 SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC-YHIEP 399
           ++ LS W+PCS +CG G+ RR  +C+    R++ + QC  H +P
Sbjct: 896 TWELSAWSPCSKSCGRGFQRRSLKCVGHGGRLLARDQCNLHRKP 939


>AJ315733-1|CAC86014.1|  950|Homo sapiens metalloprotease
           disintegrin 15 with thrombospondin domains protein.
          Length = 950

 Score =  201 bits (490), Expect = 5e-51
 Identities = 150/492 (30%), Positives = 215/492 (43%), Gaps = 62/492 (12%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLV----DNVCTTMMRPAAPGTTCGPDMWCQ 57
           +  + QC L FG  +  C  + + C  LWC        VC T   P A GT+CG    C 
Sbjct: 442 YTLSQQCELAFGVGSKPCPYM-QYCTKLWCTGKAKGQMVCQTRHFPWADGTSCGEGKLCL 500

Query: 58  NQTCVARTPSPAPR-DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
              CV R      R DG W  W  +  CSRTCG GV    R+C NP P N G YC G R 
Sbjct: 501 KGACVERHNLNKHRVDGSWAKWDPYGPCSRTCGGGVQLARRQCTNPTPANGGKYCEGVRV 560

Query: 117 RYKVCNTDPCP--INEPSFREVQCSRHNNMPYKNETID---EWVPYFDQDKP---CELQC 168
           +Y+ CN +PCP   +  SFRE QC   N   +    +     WVP +    P   C+L C
Sbjct: 561 KYRSCNLEPCPSSASGKSFREEQCEAFNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLIC 620

Query: 169 VPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGD 228
                    +L   V DGT C  +  S  +C+ G C K GCD  + S    D CGVCGGD
Sbjct: 621 RANGTGYFYVLAPKVVDGTLC--SPDSTSVCVQGKCIKAGCDGNLGSKKRFDKCGVCGGD 678

Query: 229 GTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEK-----VSPGNYISIGSTKSRR 283
             +CK V G++TK      G++ V  IPAG+ ++ I+++     +   NY+++ +++ + 
Sbjct: 679 NKSCKKVTGLFTK---PMHGYNFVVAIPAGASSIDIRQRGYKGLIGDDNYLALKNSQGKY 735

Query: 284 MFLNG--ARNATLTEYFVAGAQAIYE-RDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPG 340
           + LNG    +A   +  V G+   Y       E ++ S P+ E + V + +  G+   P 
Sbjct: 736 L-LNGHFVVSAVERDLVVKGSLLRYSGTGTAVESLQASRPILEPLTV-EVLSVGKMTPPR 793

Query: 341 VTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPP 400
           V Y + + K+    K S+      P  +                H  V+  S    +E P
Sbjct: 794 VRYSFYLPKEPREDKSSHPKDPRGPSVL----------------HNSVLSLSN--QVEQP 835

Query: 401 RHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQ 460
                    R PA   W  G+W PCS  C   G  + K R+V C      + V    C  
Sbjct: 836 -------DDRPPA--RWVAGSWGPCSASC---GSGLQK-RAVDCRGSAGQRTV--PACDA 880

Query: 461 VIKPITTIKCAD 472
             +P+ T  C +
Sbjct: 881 AHRPVETQACGE 892



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 7/68 (10%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGA 421
           W PCS +CG G  +R  +C     QR V      H  P   QA    C +P C  W + A
Sbjct: 848 WGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAH-RPVETQA----CGEP-CPTWELSA 901

Query: 422 WNPCSKLC 429
           W+PCSK C
Sbjct: 902 WSPCSKSC 909



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 1/44 (2%)

Query: 357 SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC-YHIEP 399
           ++ LS W+PCS +CG G+ RR  +C+    R++ + QC  H +P
Sbjct: 896 TWELSAWSPCSKSCGRGFQRRSLKCVGHGGRLLARDQCNLHRKP 939


>AB209685-1|BAD92922.1|  530|Homo sapiens a disintegrin and
           metalloprotease with thrombospondin motifs-6 variant
           protein.
          Length = 530

 Score =  200 bits (488), Expect = 9e-51
 Identities = 120/358 (33%), Positives = 180/358 (50%), Gaps = 28/358 (7%)

Query: 103 EPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD- 161
           +P   G YC+G+R RY+ CNTDPCP+    FRE QC+  +NMP++ +  + W PY     
Sbjct: 2   KPSGGGKYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDNMPFRGKYYN-WKPYTGGGV 60

Query: 162 KPCELQCVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDA 221
           KPC L C+             V DGT C     S D+CI+G C  VGCD I+ SD  ED 
Sbjct: 61  KPCALNCLAEGYNFYTERAPAVIDGTQCN--ADSLDICINGECKHVGCDNILGSDAREDR 118

Query: 222 CGVCGGDGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKS 281
           C VCGGDG+ C  ++G +     R  G+ EV  IP GS +++++E     NYI++ S + 
Sbjct: 119 CRVCGGDGSTCDAIEGFFNDSLPR-GGYMEVVQIPRGSVHIEVREVAMSKNYIALKS-EG 176

Query: 282 RRMFLNGARNATLTEYF-VAGAQAIYERDRDW-EKVRISGPLAEDIKVYQRIFRGRHRNP 339
              ++NGA        F VAG    Y+R  D  E +   GP +E++ V   +   + +N 
Sbjct: 177 DDYYINGAWTIDWPRKFDVAGTAFHYKRPTDEPESLEALGPTSENLIVMVLL---QEQNL 233

Query: 340 GVTYQYTVDKQRL-----HKKHSYRLSEWTPCSVTCGVGYTRRYYEC--IDQHQRVVEQS 392
           G+ Y++ V   R          ++    W+ CS TC  G  R+   C  +D +  +V+ +
Sbjct: 234 GIRYKFNVPITRTGSGDNEVGFTWNHQPWSECSATCAGGVQRQEVVCKRLDDNS-IVQNN 292

Query: 393 QC-YHIEPPRHQALMKQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKV 448
            C    +PP +Q   + C    C   W++G W  CSK C    +   + R+V C+ K+
Sbjct: 293 YCDPDSKPPENQ---RACNTEPCPPEWFIGDWLECSKTC----DGGMRTRAVLCIRKI 343



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 5/113 (4%)

Query: 360 LSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWV 419
           + +W  CS TC  G   R   CI +     E++  Y           + C   +C   WV
Sbjct: 318 IGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPVEKEPCNNQSCPPQWV 377

Query: 420 GA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCA 471
              W+ C+  C  PG    K R V C    ++K    ++C +  KP   I+C+
Sbjct: 378 ALDWSECTPKCG-PG---FKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCS 426



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 5/52 (9%)

Query: 81  WSECSRTCGAGVSTQSRECN--NPEPVNNGNYCIGDR---SRYKVCNTDPCP 127
           WSECS TC  GV  Q   C   +   +   NYC  D       + CNT+PCP
Sbjct: 262 WSECSATCAGGVQRQEVVCKRLDDNSIVQNNYCDPDSKPPENQRACNTEPCP 313



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 13/112 (11%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQC-YHIEPP-RHQALMKQCRKPACVHWW 418
           +W+ C+  CG G+  R   C      +    +QC    +PP R +  + +C  P    W 
Sbjct: 380 DWSECTPKCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSLGRCPPP---RWV 436

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            G W  CS  C + G+++   R+V C+          S+C + ++P +  +C
Sbjct: 437 TGDWGQCSAQCGL-GQQM---RTVQCLSYTGQA---SSDCLETVRPPSMQQC 481


>BC063293-1|AAH63293.1|  837|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 837

 Score =  198 bits (484), Expect = 3e-50
 Identities = 104/285 (36%), Positives = 147/285 (51%), Gaps = 19/285 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVD----NVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC L FG ++  C +L   C  LWC        +C T   P A GT CGP   C 
Sbjct: 443 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGPAQACM 502

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              C+          P+ GGWGPW  W +CSRTCG GV   SR+C  P   N G YC G 
Sbjct: 503 GGRCLHMDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVTRNGGKYCEGR 562

Query: 115 RSRYKVCNTDPCPINEP-SFREVQCSRHNNMPYKNETID---EWVPYFDQDKP---CELQ 167
           R+R++ CNT+ CP     +FRE QC+ +N+     ++     +WVP +    P   C+L 
Sbjct: 563 RARFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPQDQCKLT 622

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  +      +L   V DGTPC  +  S  +C+ G C   GCD I+ S  + D C VCGG
Sbjct: 623 CQAQALGYYYVLEPRVVDGTPC--SPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGG 680

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN 272
           DG+ C    G + K    + G++ V  IPAG+ ++ ++++ +PG+
Sbjct: 681 DGSGCSKQSGSFRK---FRYGYNNVVTIPAGATHILVRQQGNPGH 722


>AY044847-1|AAL02262.1|  837|Homo sapiens aggrecanase 1 protein.
          Length = 837

 Score =  198 bits (484), Expect = 3e-50
 Identities = 104/285 (36%), Positives = 147/285 (51%), Gaps = 19/285 (6%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSELCEHLWCLVD----NVCTTMMRPAAPGTTCGPDMWCQ 57
           +DA  QC L FG ++  C +L   C  LWC        +C T   P A GT CGP   C 
Sbjct: 443 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGPAQACM 502

Query: 58  NQTCVARTPSP---APRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGD 114
              C+          P+ GGWGPW  W +CSRTCG GV   SR+C  P P N G YC G 
Sbjct: 503 GGRCLHMDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGR 562

Query: 115 RSRYKVCNTDPCPINEP-SFREVQCSRHNNMPYKNETID---EWVPYFDQDKP---CELQ 167
           R+R++ CNT+ CP     +FRE QC+ +N+     ++     +WVP +    P   C+L 
Sbjct: 563 RTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPQDQCKLT 622

Query: 168 CVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGG 227
           C  +      +L   V DGTPC  +  S  +C+ G C   GCD I+ S  + D C VCGG
Sbjct: 623 CQAQALGYYYVLEPRVVDGTPC--SPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGG 680

Query: 228 DGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGN 272
           D + C    G + K    + G++ V  IPAG+ ++ ++++ +PG+
Sbjct: 681 DRSGCSKQSGSFRK---FRYGYNNVVTIPAGATHILVRQQGNPGH 722


>DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score =  197 bits (481), Expect = 6e-50
 Identities = 152/480 (31%), Positives = 214/480 (44%), Gaps = 48/480 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPDM 54
           + A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG + 
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEK 364

Query: 55  WCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  C
Sbjct: 365 WCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC 423

Query: 112 IGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKPC 164
           +G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  C
Sbjct: 424 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC 483

Query: 165 ELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEED 220
              C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    D
Sbjct: 484 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD 543

Query: 221 ACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGNY 273
            C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G Y
Sbjct: 544 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY 603

Query: 274 ISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQR 330
           +  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+R
Sbjct: 604 VVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYRR 660

Query: 331 IFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQR 387
                G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  + 
Sbjct: 661 YGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKE 717

Query: 388 VVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
           +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV+
Sbjct: 718 LVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCVE 771



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 1023 PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1079

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1080 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1125



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1119



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363  WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 897  WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 954

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
            W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 955  WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 1010

Query: 474  P 474
            P
Sbjct: 1011 P 1011


>AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand
           factor-cleaving protease precursor protein.
          Length = 1427

 Score =  197 bits (481), Expect = 6e-50
 Identities = 152/480 (31%), Positives = 214/480 (44%), Gaps = 48/480 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPDM 54
           + A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG + 
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEK 364

Query: 55  WCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  C
Sbjct: 365 WCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC 423

Query: 112 IGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKPC 164
           +G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  C
Sbjct: 424 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC 483

Query: 165 ELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEED 220
              C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    D
Sbjct: 484 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD 543

Query: 221 ACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGNY 273
            C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G Y
Sbjct: 544 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY 603

Query: 274 ISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQR 330
           +  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+R
Sbjct: 604 VVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYRR 660

Query: 331 IFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQR 387
                G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  + 
Sbjct: 661 YGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKE 717

Query: 388 VVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
           +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV+
Sbjct: 718 LVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCVE 771



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 1023 PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1079

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1080 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1125



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1119



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363  WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 897  WTPVAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 954

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
            W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 955  WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 1010

Query: 474  P 474
            P
Sbjct: 1011 P 1011


>AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1371

 Score =  197 bits (481), Expect = 6e-50
 Identities = 152/480 (31%), Positives = 214/480 (44%), Gaps = 48/480 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPDM 54
           + A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG + 
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEK 364

Query: 55  WCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  C
Sbjct: 365 WCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC 423

Query: 112 IGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKPC 164
           +G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  C
Sbjct: 424 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC 483

Query: 165 ELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEED 220
              C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    D
Sbjct: 484 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD 543

Query: 221 ACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGNY 273
            C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G Y
Sbjct: 544 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY 603

Query: 274 ISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQR 330
           +  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+R
Sbjct: 604 VVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYRR 660

Query: 331 IFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQR 387
                G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  + 
Sbjct: 661 YGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKE 717

Query: 388 VVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
           +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV+
Sbjct: 718 LVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCVE 771



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 1023 PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1079

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1080 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1125



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1119



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363  WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 897  WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 954

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
            W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 955  WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 1010

Query: 474  P 474
            P
Sbjct: 1011 P 1011


>AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score =  197 bits (481), Expect = 6e-50
 Identities = 152/480 (31%), Positives = 214/480 (44%), Gaps = 48/480 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPDM 54
           + A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG + 
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEK 364

Query: 55  WCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  C
Sbjct: 365 WCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC 423

Query: 112 IGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKPC 164
           +G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  C
Sbjct: 424 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC 483

Query: 165 ELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEED 220
              C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    D
Sbjct: 484 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD 543

Query: 221 ACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGNY 273
            C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G Y
Sbjct: 544 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY 603

Query: 274 ISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQR 330
           +  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+R
Sbjct: 604 VVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYRR 660

Query: 331 IFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQR 387
                G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  + 
Sbjct: 661 YGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKE 717

Query: 388 VVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
           +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV+
Sbjct: 718 LVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCVE 771



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 1023 PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1079

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1080 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1125



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1119



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363  WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 897  WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 954

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
            W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 955  WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 1010

Query: 474  P 474
            P
Sbjct: 1011 P 1011


>AL158826-24|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score =  197 bits (481), Expect = 6e-50
 Identities = 152/480 (31%), Positives = 214/480 (44%), Gaps = 48/480 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPDM 54
           + A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG + 
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEK 364

Query: 55  WCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  C
Sbjct: 365 WCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC 423

Query: 112 IGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKPC 164
           +G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  C
Sbjct: 424 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC 483

Query: 165 ELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEED 220
              C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    D
Sbjct: 484 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD 543

Query: 221 ACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGNY 273
            C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G Y
Sbjct: 544 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY 603

Query: 274 ISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQR 330
           +  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+R
Sbjct: 604 VVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYRR 660

Query: 331 IFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQR 387
                G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  + 
Sbjct: 661 YGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKE 717

Query: 388 VVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
           +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV+
Sbjct: 718 LVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCVE 771



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 1023 PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1079

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1080 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1125



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1119



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363  WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 897  WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 954

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
            W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 955  WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 1010

Query: 474  P 474
            P
Sbjct: 1011 P 1011


>AL158826-22|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1371

 Score =  197 bits (481), Expect = 6e-50
 Identities = 152/480 (31%), Positives = 214/480 (44%), Gaps = 48/480 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPDM 54
           + A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG + 
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEK 364

Query: 55  WCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  C
Sbjct: 365 WCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC 423

Query: 112 IGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKPC 164
           +G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  C
Sbjct: 424 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC 483

Query: 165 ELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEED 220
              C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    D
Sbjct: 484 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD 543

Query: 221 ACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGNY 273
            C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G Y
Sbjct: 544 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY 603

Query: 274 ISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQR 330
           +  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+R
Sbjct: 604 VVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYRR 660

Query: 331 IFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQR 387
                G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  + 
Sbjct: 661 YGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKE 717

Query: 388 VVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
           +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV+
Sbjct: 718 LVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCVE 771



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 1023 PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1079

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1080 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1125



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1119



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363  WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 897  WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 954

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
            W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 955  WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 1010

Query: 474  P 474
            P
Sbjct: 1011 P 1011


>AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, variant
           2 protein.
          Length = 1371

 Score =  197 bits (481), Expect = 6e-50
 Identities = 152/480 (31%), Positives = 214/480 (44%), Gaps = 48/480 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPDM 54
           + A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG + 
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEK 364

Query: 55  WCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  C
Sbjct: 365 WCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC 423

Query: 112 IGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKPC 164
           +G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  C
Sbjct: 424 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC 483

Query: 165 ELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEED 220
              C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    D
Sbjct: 484 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD 543

Query: 221 ACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGNY 273
            C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G Y
Sbjct: 544 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY 603

Query: 274 ISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQR 330
           +  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+R
Sbjct: 604 VVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYRR 660

Query: 331 IFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQR 387
                G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  + 
Sbjct: 661 YGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKE 717

Query: 388 VVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
           +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV+
Sbjct: 718 LVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCVE 771



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 1023 PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1079

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1080 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1125



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1119



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363  WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 897  WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 954

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
            W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 955  WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 1010

Query: 474  P 474
            P
Sbjct: 1011 P 1011


>AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.
          Length = 1427

 Score =  197 bits (481), Expect = 6e-50
 Identities = 152/480 (31%), Positives = 214/480 (44%), Gaps = 48/480 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPDM 54
           + A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG + 
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEK 364

Query: 55  WCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  C
Sbjct: 365 WCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC 423

Query: 112 IGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKPC 164
           +G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  C
Sbjct: 424 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC 483

Query: 165 ELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEED 220
              C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    D
Sbjct: 484 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD 543

Query: 221 ACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGNY 273
            C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G Y
Sbjct: 544 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY 603

Query: 274 ISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQR 330
           +  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+R
Sbjct: 604 VVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYRR 660

Query: 331 IFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQR 387
                G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  + 
Sbjct: 661 YGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKE 717

Query: 388 VVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
           +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV+
Sbjct: 718 LVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCVE 771



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 1023 PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1079

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1080 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1125



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1119



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363  WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 897  WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 954

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
            W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 955  WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 1010

Query: 474  P 474
            P
Sbjct: 1011 P 1011


>AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand
           factor-cleaving protease protein.
          Length = 1427

 Score =  197 bits (481), Expect = 6e-50
 Identities = 152/480 (31%), Positives = 214/480 (44%), Gaps = 48/480 (10%)

Query: 2   FDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPDM 54
           + A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG + 
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEK 364

Query: 55  WCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  C
Sbjct: 365 WCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC 423

Query: 112 IGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKPC 164
           +G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  C
Sbjct: 424 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC 483

Query: 165 ELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEED 220
              C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    D
Sbjct: 484 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD 543

Query: 221 ACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGNY 273
            C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G Y
Sbjct: 544 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY 603

Query: 274 ISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQR 330
           +  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+R
Sbjct: 604 VVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYRR 660

Query: 331 IFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQR 387
                G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  + 
Sbjct: 661 YGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKE 717

Query: 388 VVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
           +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV+
Sbjct: 718 LVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCVE 771



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 1023 PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1079

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1080 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1125



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1119



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363  WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
            WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 897  WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 954

Query: 418  WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
            W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 955  WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 1010

Query: 474  P 474
            P
Sbjct: 1011 P 1011


>AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 13 protein.
          Length = 1340

 Score =  197 bits (480), Expect = 8e-50
 Identities = 152/481 (31%), Positives = 214/481 (44%), Gaps = 48/481 (9%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPD 53
           +  A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG +
Sbjct: 273 LLSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVE 332

Query: 54  MWCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNY 110
            WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  
Sbjct: 333 KWCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRA 391

Query: 111 CIGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKP 163
           C+G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  
Sbjct: 392 CVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDAL 451

Query: 164 CELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEE 219
           C   C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    
Sbjct: 452 CRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVW 511

Query: 220 DACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGN 272
           D C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G 
Sbjct: 512 DRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGR 571

Query: 273 YISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQ 329
           Y+  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+
Sbjct: 572 YVVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYR 628

Query: 330 RIFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQ 386
           R     G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  +
Sbjct: 629 RYGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARK 685

Query: 387 RVVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCV 445
            +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV
Sbjct: 686 ELVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCV 739

Query: 446 D 446
           +
Sbjct: 740 E 740



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 992  PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1048

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1049 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1094



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1043 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1088



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363 WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
           WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 866 WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 923

Query: 418 WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
           W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 924 WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 979

Query: 474 P 474
           P
Sbjct: 980 P 980


>AL158826-23|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1340

 Score =  197 bits (480), Expect = 8e-50
 Identities = 152/481 (31%), Positives = 214/481 (44%), Gaps = 48/481 (9%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPD 53
           +  A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG +
Sbjct: 273 LLSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVE 332

Query: 54  MWCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNY 110
            WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  
Sbjct: 333 KWCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRA 391

Query: 111 CIGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKP 163
           C+G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  
Sbjct: 392 CVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDAL 451

Query: 164 CELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEE 219
           C   C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    
Sbjct: 452 CRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVW 511

Query: 220 DACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGN 272
           D C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G 
Sbjct: 512 DRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGR 571

Query: 273 YISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQ 329
           Y+  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+
Sbjct: 572 YVVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYR 628

Query: 330 RIFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQ 386
           R     G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  +
Sbjct: 629 RYGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARK 685

Query: 387 RVVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCV 445
            +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV
Sbjct: 686 ELVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCV 739

Query: 446 D 446
           +
Sbjct: 740 E 740



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 992  PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1048

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1049 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1094



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1043 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1088



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363 WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
           WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 866 WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 923

Query: 418 WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
           W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 924 WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 979

Query: 474 P 474
           P
Sbjct: 980 P 980


>AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.
          Length = 1340

 Score =  197 bits (480), Expect = 8e-50
 Identities = 152/481 (31%), Positives = 214/481 (44%), Gaps = 48/481 (9%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSE---LCEHLWCLVDNV----CTTMMRPAAPGTTCGPD 53
           +  A  QC + FG +A  C+   E   +C+ L C  D +    C+ ++ P   GT CG +
Sbjct: 273 LLSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVE 332

Query: 54  MWCQNQTC---VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNY 110
            WC    C   V  TP  A   G W  W   S CSR+CG GV T+ R+CNNP P   G  
Sbjct: 333 KWCSKGRCRSLVELTPIAAVH-GRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRA 391

Query: 111 CIGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNE----TIDEW---VPYFDQDKP 163
           C+G   + ++CNT  C   +  F   QC+R +  P ++     +   W   VP+   D  
Sbjct: 392 CVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDAL 451

Query: 164 CELQCVPRDGTDVEMLGGFVADGTPCR----QAIGSRDMCISGVCYKVGCDWIVDSDVEE 219
           C   C     + +   G    DGT C     +  G+  +C+SG C   GCD  +DS    
Sbjct: 452 CRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVW 511

Query: 220 DACGVCGGDGTACKTVQGIYTKGTTRQ-SGFSEV-----AIIPAGSRNVKIQEKVS-PGN 272
           D C VCGGD + C   +G +T G  R+   F  V     ++  A  R +     V   G 
Sbjct: 512 DRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGR 571

Query: 273 YISIGSTK-SRRMFLNGARNATLTEYFVAGAQAIYERDRDWEKVRISGPLAE--DIKVYQ 329
           Y+  G    S              EY VA  +   +R    E++RI GPL E  DI+VY+
Sbjct: 572 YVVAGKMSISPNTTYPSLLEDGRVEYRVALTE---DRLPRLEEIRIWGPLQEDADIQVYR 628

Query: 330 RIFR--GRHRNPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQ 386
           R     G    P +T+ Y   K R   +     +   PCSV+CG G     Y C+DQ  +
Sbjct: 629 RYGEEYGNLTRPDITFTYFQPKPR---QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARK 685

Query: 387 RVVEQSQCYHIEPPRHQALMKQC-RKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCV 445
            +VE  QC   + P   A  + C  +P   +W VG + PCS  C   G  + +ER V CV
Sbjct: 686 ELVETVQCQGSQQP--PAWPEACVLEPCPPYWAVGDFGPCSASC---GGGL-RERPVRCV 739

Query: 446 D 446
           +
Sbjct: 740 E 740



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365  PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
            PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 992  PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 1048

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 1049 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 1094



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356  HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
            + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 1043 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 1088



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363 WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
           WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 866 WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 923

Query: 418 WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
           W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 924 WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 979

Query: 474 P 474
           P
Sbjct: 980 P 980


>BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein.
          Length = 1682

 Score =  195 bits (476), Expect = 2e-49
 Identities = 119/354 (33%), Positives = 171/354 (48%), Gaps = 24/354 (6%)

Query: 65  TPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD 124
           T S   +DG W  W +WS+CSRTCG G S   R C        G  C G   RYK C+  
Sbjct: 68  TRSDEDKDGNWDAWGDWSDCSRTCGGGASYSLRRCLT------GRNCEGQNIRYKTCSNH 121

Query: 125 PCPINEPSFREVQCSRHNNMPYKNETIDEWVP-YFDQDKPCELQCVPRDGTDVEMLGGFV 183
            CP +   FR  QCS +N++ Y+     EW+P Y D   PC L+C  +    V  L   V
Sbjct: 122 DCPPDAEDFRAQQCSAYNDVQYQGHYY-EWLPRYNDPAAPCALKCHAQGQNLVVELAPKV 180

Query: 184 ADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGT 243
            DGT C     S DMCISG+C  VGCD  + S+ +ED CGVC GDG+ C+ V+G      
Sbjct: 181 LDGTRCNT--DSLDMCISGICQAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHV 238

Query: 244 TRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYFVAGAQ 303
           + +     V  +P GSR+V+I  K     +I   + +  +    G  +      FV    
Sbjct: 239 SPEKREENVIAVPLGSRSVRITVKGPAHLFIESKTLQGSK----GEHSFNSPGVFVVENT 294

Query: 304 AI-YERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHSYRLSE 362
            + ++R  + +  +I GPL  D      IF+ R+     +       Q +   H +R ++
Sbjct: 295 TVEFQRGSERQTFKIPGPLMADF-----IFKTRYTAAKDSVVQFFFYQPI--SHQWRQTD 347

Query: 363 WTPCSVTCGVGYTRRYYECID-QHQRVVEQSQC-YHIEPPRHQALMKQCRKPAC 414
           + PC+VTCG GY     EC+D + +RVV    C Y+ E  + +  +K+C    C
Sbjct: 348 FFPCTVTCGGGYQLNSAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPC 401



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 8/92 (8%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECID-QHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           + +  + +TPC+ TC  G+      C+  Q Q+ V  S C  +  P   A+ + C    C
Sbjct: 646 YDWEYAGFTPCTATCLGGHQEAIAVCLHIQTQQTVNDSLCDMVHRP--PAMSQACNTEPC 703

Query: 415 V-HWWVGAWNPCSKLCHMPGEEVTKERSVYCV 445
              W VG+W PCS  C +      + R VYC+
Sbjct: 704 PPRWHVGSWGPCSATCGVG----IQTRDVYCL 731



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 7/71 (9%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQ--HQRV--VEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
           WT CSV+CG G  RR + C+++  H  +  VE+ +C +   P+   +M+ C    C  W 
Sbjct: 427 WTACSVSCGGGIQRRSFVCVEESMHGEILQVEEWKCMYAPKPK---VMQTCNLFDCPKWI 483

Query: 419 VGAWNPCSKLC 429
              W+ C+  C
Sbjct: 484 AMEWSQCTVTC 494



 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 5/73 (6%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VH 416
           + +  W PCS TCGVG   R   C+   +      +C   +P   QA    C +  C   
Sbjct: 707 WHVGSWGPCSATCGVGIQTRDVYCLHPGETPAPPEECRDEKPHALQA----CNQFDCPPG 762

Query: 417 WWVGAWNPCSKLC 429
           W +  W  CS+ C
Sbjct: 763 WHIEEWQQCSRTC 775



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 11/117 (9%)

Query: 363  WTPCSVTCG-VGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVG 420
            W+ CS TCG +G   +  +C+  + + V ++ C H++ P   A  + C    C   W+  
Sbjct: 1433 WSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHLQKP--LAGFEPCNIRDCPARWFTS 1490

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMN---KVVDDSECGQVIKPITTIKCADVP 474
             W+ CS  C   GE     R V C     N   +VV    C    +P+    C   P
Sbjct: 1491 VWSQCSVSC---GEGY-HSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPCFGHP 1543



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 6/94 (6%)

Query: 384  QHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSV 442
            +H      S   + +  +   L + C   AC V W  G W PC+  C   G    + R V
Sbjct: 1567 RHTACQHNSSDSNCDDRKRPTLRRNCTSGACDVCWHTGPWKPCTAAC---GRGF-QSRKV 1622

Query: 443  YCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
             C+     K V    C Q  KPI+   C   P+C
Sbjct: 1623 DCIHTRSCKPVAKRHCVQKKKPISWRHCLG-PSC 1655



 Score = 37.1 bits (82), Expect = 0.13
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 8/85 (9%)

Query: 58  NQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP-EPVNNGNYCIGDRS 116
           +Q C      P    G WGP      CS TCG G+ T+   C +P E       C  ++ 
Sbjct: 695 SQACNTEPCPPRWHVGSWGP------CSATCGVGIQTRDVYCLHPGETPAPPEECRDEKP 748

Query: 117 R-YKVCNTDPCPINEPSFREVQCSR 140
              + CN   CP         QCSR
Sbjct: 749 HALQACNQFDCPPGWHIEEWQQCSR 773



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 12/91 (13%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           PG T  P   C+++   A +  +      GW    EW +CSRTCG G  TQ+R     + 
Sbjct: 733 PGETPAPPEECRDEKPHALQACNQFDCPPGWHI-EEWQQCSRTCGGG--TQNRRVTCRQL 789

Query: 105 VNNGNY-------CIGDR-SRYKVCNTDPCP 127
           + +G++       C G + S +K C    CP
Sbjct: 790 LTDGSFLNLSDELCQGPKASSHKSCARTDCP 820



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 30/111 (27%), Positives = 41/111 (36%), Gaps = 4/111 (3%)

Query: 361  SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQAL-MKQCRKPACVHWWV 419
            S W+ CSV+CG GY  R   C         Q        P+ + L  K C    CV W  
Sbjct: 1490 SVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPCFGHPCVQWEP 1549

Query: 420  GAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            G  N C   C M      ++R   C     +   DD +   + +  T+  C
Sbjct: 1550 G--NRCPGRC-MGRAVRMQQRHTACQHNSSDSNCDDRKRPTLRRNCTSGAC 1597



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 6/80 (7%)

Query: 65   TPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSREC--NNPEPVNNG--NYCIGDRSRYK 119
            T  P P++  W P   WS CS TCG  G   Q  +C   N + V+    ++     + ++
Sbjct: 1418 TGEPPPQEPFWEP-GNWSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHLQKPLAGFE 1476

Query: 120  VCNTDPCPINEPSFREVQCS 139
             CN   CP    +    QCS
Sbjct: 1477 PCNIRDCPARWFTSVWSQCS 1496



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 9/71 (12%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNP--EPVNNGNYC------IGDRSRYKVCNTDPCPINE 130
           +++  C+ TCG G    S EC +   + V   +YC      +  + + K C+ DPCP ++
Sbjct: 346 TDFFPCTVTCGGGYQLNSAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPCPSSD 405

Query: 131 PSFREVQCSRH 141
             F+E+    H
Sbjct: 406 -GFKEIMPYDH 415



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 9/77 (11%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC----IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           + + EW  CS TCG G   R   C     D     +    C   +   H    K C +  
Sbjct: 763 WHIEEWQQCSRTCGGGTQNRRVTCRQLLTDGSFLNLSDELCQGPKASSH----KSCARTD 818

Query: 414 C-VHWWVGAWNPCSKLC 429
           C  H  VG W+ CS  C
Sbjct: 819 CPPHLAVGDWSKCSVSC 835



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 360 LSEWTPCSVTCGVGYTRRYYEC--IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           + +W+ CSV+CGVG  RR   C  +    R +  S+    + P    L++ C+ P C
Sbjct: 825 VGDWSKCSVSCGVGIQRRKQVCQRLAAKGRRIPLSEMMCRDLPGF-PLVRSCQMPEC 880



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 2/52 (3%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
            W PC+  CG G+  R  +CI  H R  +     H    +     + C  P+C
Sbjct: 1606 WKPCTAACGRGFQSRKVDCI--HTRSCKPVAKRHCVQKKKPISWRHCLGPSC 1655


>BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein.
          Length = 1691

 Score =  195 bits (476), Expect = 2e-49
 Identities = 119/354 (33%), Positives = 171/354 (48%), Gaps = 24/354 (6%)

Query: 65  TPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD 124
           T S   +DG W  W +WS+CSRTCG G S   R C        G  C G   RYK C+  
Sbjct: 68  TRSDEDKDGNWDAWGDWSDCSRTCGGGASYSLRRCLT------GRNCEGQNIRYKTCSNH 121

Query: 125 PCPINEPSFREVQCSRHNNMPYKNETIDEWVP-YFDQDKPCELQCVPRDGTDVEMLGGFV 183
            CP +   FR  QCS +N++ Y+     EW+P Y D   PC L+C  +    V  L   V
Sbjct: 122 DCPPDAEDFRAQQCSAYNDVQYQGRYY-EWLPRYNDPAAPCALKCHAQGQNLVVELAPKV 180

Query: 184 ADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGT 243
            DGT C     S DMCISG+C  VGCD  + S+ +ED CGVC GDG+ C+ V+G      
Sbjct: 181 LDGTRCNT--DSLDMCISGICQAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHV 238

Query: 244 TRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYFVAGAQ 303
           + +     V  +P GSR+V+I  K     +I   + +  +    G  +      FV    
Sbjct: 239 SPEKREENVIAVPLGSRSVRITVKGPAHLFIESKTLQGSK----GEHSFNSPGVFVVENT 294

Query: 304 AI-YERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHSYRLSE 362
            + ++R  + +  +I GPL  D      IF+ R+     +       Q +   H +R ++
Sbjct: 295 TVEFQRGSERQTFKIPGPLMADF-----IFKTRYTAAKDSVVQFFFYQPI--SHQWRQTD 347

Query: 363 WTPCSVTCGVGYTRRYYECID-QHQRVVEQSQC-YHIEPPRHQALMKQCRKPAC 414
           + PC+VTCG GY     EC+D + +RVV    C Y+ E  + +  +K+C    C
Sbjct: 348 FFPCTVTCGGGYQLNSAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPC 401



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 8/92 (8%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECID-QHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           + +  + +TPC+ TC  G+      C+  Q Q+ V  S C  +  P   A+ + C    C
Sbjct: 646 YDWEYAGFTPCTATCLGGHQEAIAVCLHIQTQQTVNDSLCDMVHRP--PAMSQACNTEPC 703

Query: 415 V-HWWVGAWNPCSKLCHMPGEEVTKERSVYCV 445
              W VG+W PCS  C +      + R VYC+
Sbjct: 704 PPRWHVGSWGPCSATCGVG----IQTRDVYCL 731



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 7/71 (9%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQ--HQRV--VEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
           WT CSV+CG G  RR + C+++  H  +  VE+ +C +   P+   +M+ C    C  W 
Sbjct: 427 WTACSVSCGGGIQRRSFVCVEESMHGEILQVEEWKCMYAPKPK---VMQTCNLFDCPKWI 483

Query: 419 VGAWNPCSKLC 429
              W+ C+  C
Sbjct: 484 AMEWSQCTVTC 494



 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 5/73 (6%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VH 416
           + +  W PCS TCGVG   R   C+   +      +C   +P   QA    C +  C   
Sbjct: 707 WHVGSWGPCSATCGVGIQTRDVYCLHPGETPAPPEECRDEKPHALQA----CNQFDCPPG 762

Query: 417 WWVGAWNPCSKLC 429
           W +  W  CS+ C
Sbjct: 763 WHIEEWQQCSRTC 775



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 11/117 (9%)

Query: 363  WTPCSVTCG-VGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVG 420
            W+ CS TCG +G   +  +C+  + + V ++ C H++ P   A  + C    C   W+  
Sbjct: 1433 WSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHLQKP--LAGFEPCNIRDCPARWFTS 1490

Query: 421  AWNPCSKLCHMPGEEVTKERSVYCVDKVMN---KVVDDSECGQVIKPITTIKCADVP 474
             W+ CS  C   GE     R V C     N   +VV    C    +P+    C   P
Sbjct: 1491 VWSQCSVSC---GEGY-HSRQVTCKRTKANGTVQVVSPRSCAPKDRPLGRKPCFGHP 1543



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 6/94 (6%)

Query: 384  QHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSV 442
            +H      S   + +  +   L + C   AC V W  G W PC+  C   G    + R V
Sbjct: 1567 RHTACQHNSSDSNCDDRKRPTLRRNCTSGACDVCWHTGPWKPCTAAC---GRGF-QSRKV 1622

Query: 443  YCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
             C+     K V    C Q  KPI+   C   P+C
Sbjct: 1623 DCIHTRSCKPVAKRHCVQKKKPISWRHCLG-PSC 1655



 Score = 37.1 bits (82), Expect = 0.13
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 8/85 (9%)

Query: 58  NQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP-EPVNNGNYCIGDRS 116
           +Q C      P    G WGP      CS TCG G+ T+   C +P E       C  ++ 
Sbjct: 695 SQACNTEPCPPRWHVGSWGP------CSATCGVGIQTRDVYCLHPGETPAPPEECRDEKP 748

Query: 117 R-YKVCNTDPCPINEPSFREVQCSR 140
              + CN   CP         QCSR
Sbjct: 749 HALQACNQFDCPPGWHIEEWQQCSR 773



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 12/91 (13%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           PG T  P   C+++   A +  +      GW    EW +CSRTCG G  TQ+R     + 
Sbjct: 733 PGETPAPPEECRDEKPHALQACNQFDCPPGWHI-EEWQQCSRTCGGG--TQNRRVTCRQL 789

Query: 105 VNNGNY-------CIGDR-SRYKVCNTDPCP 127
           + +G++       C G + S +K C    CP
Sbjct: 790 LTDGSFLNLSDELCQGPKASSHKSCARTDCP 820



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 30/111 (27%), Positives = 41/111 (36%), Gaps = 4/111 (3%)

Query: 361  SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQAL-MKQCRKPACVHWWV 419
            S W+ CSV+CG GY  R   C         Q        P+ + L  K C    CV W  
Sbjct: 1490 SVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRSCAPKDRPLGRKPCFGHPCVQWEP 1549

Query: 420  GAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            G  N C   C M      ++R   C     +   DD +   + +  T+  C
Sbjct: 1550 G--NRCPGRC-MGRAVRMQQRHTACQHNSSDSNCDDRKRPTLRRNCTSGAC 1597



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 6/80 (7%)

Query: 65   TPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSREC--NNPEPVNNG--NYCIGDRSRYK 119
            T  P P++  W P   WS CS TCG  G   Q  +C   N + V+    ++     + ++
Sbjct: 1418 TGEPPPQEPFWEP-GNWSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHLQKPLAGFE 1476

Query: 120  VCNTDPCPINEPSFREVQCS 139
             CN   CP    +    QCS
Sbjct: 1477 PCNIRDCPARWFTSVWSQCS 1496



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 9/71 (12%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNP--EPVNNGNYC------IGDRSRYKVCNTDPCPINE 130
           +++  C+ TCG G    S EC +   + V   +YC      +  + + K C+ DPCP ++
Sbjct: 346 TDFFPCTVTCGGGYQLNSAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPCPSSD 405

Query: 131 PSFREVQCSRH 141
             F+E+    H
Sbjct: 406 -GFKEIMPYDH 415



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 9/77 (11%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC----IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           + + EW  CS TCG G   R   C     D     +    C   +   H    K C +  
Sbjct: 763 WHIEEWQQCSRTCGGGTQNRRVTCRQLLTDGSFLNLSDELCQGPKASSH----KSCARTD 818

Query: 414 C-VHWWVGAWNPCSKLC 429
           C  H  VG W+ CS  C
Sbjct: 819 CPPHLAVGDWSKCSVSC 835



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 2/52 (3%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
            W PC+  CG G+  R  +CI  H R  +     H    +     + C  P+C
Sbjct: 1606 WKPCTAACGRGFQSRKVDCI--HTRSCKPVAKRHCVQKKKPISWRHCLGPSC 1655



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 360 LSEWTPCSVTCGVGYTRRYYEC--IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           + +W+ CSV+CGVG  RR   C  +    R +  S+    + P    L++ C+ P C
Sbjct: 825 VGDWSKCSVSCGVGIQRRKQVCQRLAAKGRRIPLSEMMCRDLP-GLPLVRSCQMPEC 880


>AL353895-1|CAI14851.1|  525|Homo sapiens ADAMTS-like 1 protein.
          Length = 525

 Score =  195 bits (475), Expect = 3e-49
 Identities = 120/352 (34%), Positives = 173/352 (49%), Gaps = 24/352 (6%)

Query: 67  SPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           S   RDG W  W  WSECSRTCG G S   R C + +       C G   RY+ C+   C
Sbjct: 28  SEEDRDGLWDAWGPWSECSRTCGGGASYSLRRCLSSKS------CEGRNIRYRTCSNVDC 81

Query: 127 PINEPSFREVQCSRHNNMPYKNETIDEWVPYF-DQDKPCELQCVPRDGTDVEMLGGFVAD 185
           P     FR  QCS HN++ +  +   EW+P   D D PC L+C  +  T V  L   V D
Sbjct: 82  PPEAGDFRAQQCSAHNDVKHHGQFY-EWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLD 140

Query: 186 GTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTR 245
           GT C     S DMCISG+C  VGCD  + S V+ED CGVC GDG+ C+ V+G Y    + 
Sbjct: 141 GTRCYTE--SLDMCISGLCQIVGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSA 198

Query: 246 QSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYFVAGAQAI 305
                 V  IP GSR++++  K     Y+   + +  +    G  + + T  F+    ++
Sbjct: 199 TKSDDTVVAIPYGSRHIRLVLKGPDHLYLETKTLQGTK----GENSLSSTGTFLVDNSSV 254

Query: 306 -YERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHSYRLSEWT 364
            +++  D E +R++GPL  D  V  R       +   T Q+   +  +H+   +R +++ 
Sbjct: 255 DFQKFPDKEILRMAGPLTADFIVKIR----NSGSADSTVQFIFYQPIIHR---WRETDFF 307

Query: 365 PCSVTCGVGYTRRYYECID-QHQRVVEQSQC-YHIEPPRHQALMKQCRKPAC 414
           PCS TCG GY     EC D +  RVV    C Y+ E  + +  +++C    C
Sbjct: 308 PCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPC 359



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 14/138 (10%)

Query: 343 YQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIE 398
           Y+  +     H    +  + WT CS +CG G   R   C+++    H   VE+ +C +  
Sbjct: 365 YKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKCMY-- 422

Query: 399 PPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            P+   + + C    C  W    W+PC+  C   G+ + + R V C+D   ++ +    C
Sbjct: 423 TPK-MPIAQPCNIFDCPKWLAQEWSPCTVTC---GQGL-RYRVVLCID---HRGMHTGGC 474

Query: 459 GQVIKPITTIKCADVPAC 476
               KP    +C     C
Sbjct: 475 SPKTKPHIKEECIVPTPC 492



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 8/60 (13%)

Query: 79  SEWSECSRTCGAGVSTQSRECNN--PEPVNNGNYC------IGDRSRYKVCNTDPCPINE 130
           +++  CS TCG G    S EC +     V    YC      I  + + + CN DPCP ++
Sbjct: 304 TDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPASD 363


>AF237652-1|AAK15041.1|  766|Homo sapiens a disintegrin-like and
           metalloprotease domain with thrombospondin type I motifs
           protein.
          Length = 766

 Score =  195 bits (475), Expect = 3e-49
 Identities = 119/354 (33%), Positives = 171/354 (48%), Gaps = 24/354 (6%)

Query: 65  TPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD 124
           T S   +DG W  W +WS+CSRTCG G S   R C        G  C G   RYK C+  
Sbjct: 68  TRSDEDKDGNWDAWGDWSDCSRTCGGGASYSLRRCLT------GRNCEGQNIRYKTCSNH 121

Query: 125 PCPINEPSFREVQCSRHNNMPYKNETIDEWVP-YFDQDKPCELQCVPRDGTDVEMLGGFV 183
            CP +   FR  QCS +N++ Y+     EW+P Y D   PC L+C  +    V  L   V
Sbjct: 122 DCPPDAEDFRAQQCSAYNDVQYQGHYY-EWLPRYNDPAAPCALKCHAQGQNLVVELAPKV 180

Query: 184 ADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGT 243
            DGT C     S DMCISG+C  VGCD  + S+ +ED CGVC GDG+ C+ V+G      
Sbjct: 181 LDGTRCNT--DSLDMCISGICQAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHV 238

Query: 244 TRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYFVAGAQ 303
           + +     V  +P GSR+V+I  K     +I   + +  +    G  +      FV    
Sbjct: 239 SPEKREENVIAVPLGSRSVRITVKGPVHLFIESKTLQGSK----GEHSFNSPGVFVVENT 294

Query: 304 AI-YERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHSYRLSE 362
            + ++R  + +  +I GPL  D      IF+ R+     +       Q +   H +R ++
Sbjct: 295 TVEFQRGSERQTFKIPGPLMADF-----IFKTRYTAAKDSVVQFFFYQPI--SHQWRQTD 347

Query: 363 WTPCSVTCGVGYTRRYYECID-QHQRVVEQSQC-YHIEPPRHQALMKQCRKPAC 414
           + PC+VTCG GY     EC+D + +RVV    C Y+ E  + +  +K+C    C
Sbjct: 348 FFPCTVTCGGGYQLNSAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPC 401



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 8/92 (8%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECID-QHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           + +  + +TPC+ TC  G+      C+  Q Q+ V  S C  +  P   A+ + C    C
Sbjct: 646 YDWEYAGFTPCTATCLGGHQEAIAVCLHIQTQQTVNDSLCDMVHRP--PAMSQACNTEPC 703

Query: 415 V-HWWVGAWNPCSKLCHMPGEEVTKERSVYCV 445
              W VG+W PCS  C +      + R VYC+
Sbjct: 704 PPRWHVGSWGPCSATCGVG----IQTRDVYCL 731



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 7/71 (9%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQ--HQRV--VEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
           WT CSV+CG G  RR + C+++  H  +  VE+ +C +   P+   +M+ C    C  W 
Sbjct: 427 WTACSVSCGGGIQRRSFVCVEESMHGEILQVEEWKCMYAPKPK---VMQTCNLFDCPKWI 483

Query: 419 VGAWNPCSKLC 429
              W+ C+  C
Sbjct: 484 AMEWSQCTVTC 494



 Score = 35.9 bits (79), Expect = 0.31
 Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 4/61 (6%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
           + +  W PCS TCGVG   R   C+   +      +C   +P   QA    C +  C   
Sbjct: 707 WHVGSWGPCSATCGVGIQTRDVYCLHPGETPAPPEECRDEKPHALQA----CNQFDCPPG 762

Query: 418 W 418
           W
Sbjct: 763 W 763



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 22/72 (30%), Positives = 29/72 (40%), Gaps = 8/72 (11%)

Query: 58  NQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP-EPVNNGNYCIGDRS 116
           +Q C      P    G WGP      CS TCG G+ T+   C +P E       C  ++ 
Sbjct: 695 SQACNTEPCPPRWHVGSWGP------CSATCGVGIQTRDVYCLHPGETPAPPEECRDEKP 748

Query: 117 R-YKVCNTDPCP 127
              + CN   CP
Sbjct: 749 HALQACNQFDCP 760



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 9/71 (12%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNP--EPVNNGNYC------IGDRSRYKVCNTDPCPINE 130
           +++  C+ TCG G    S EC +   + V   +YC      +  + + K C+ DPCP ++
Sbjct: 346 TDFFPCTVTCGGGYQLNSAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPCPSSD 405

Query: 131 PSFREVQCSRH 141
             F+E+    H
Sbjct: 406 -GFKEIMPYDH 415


>AF176313-1|AAK84170.1|  525|Homo sapiens ADAM-TS related protein 1
           protein.
          Length = 525

 Score =  194 bits (474), Expect = 4e-49
 Identities = 119/352 (33%), Positives = 173/352 (49%), Gaps = 24/352 (6%)

Query: 67  SPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           S   RDG W  W  WSECSRTCG G +   R C + +       C G   RY+ C+   C
Sbjct: 28  SEEDRDGLWDAWGPWSECSRTCGGGAANSLRRCLSSKS------CEGRNIRYRTCSNVDC 81

Query: 127 PINEPSFREVQCSRHNNMPYKNETIDEWVPYF-DQDKPCELQCVPRDGTDVEMLGGFVAD 185
           P     FR  QCS HN++ +  +   EW+P   D D PC L+C  +  T V  L   V D
Sbjct: 82  PPEAGDFRAQQCSAHNDVKHHGQFY-EWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLD 140

Query: 186 GTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTR 245
           GT C     S DMCISG+C  VGCD  + S V+ED CGVC GDG+ C+ V+G Y    + 
Sbjct: 141 GTRCYTE--SLDMCISGLCQIVGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSA 198

Query: 246 QSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYFVAGAQAI 305
                 V  IP GSR++++  K     Y+   + +  +    G  + + T  F+    ++
Sbjct: 199 TKSDDTVVAIPYGSRHIRLVLKGPDHLYLETKTLQGTK----GENSLSSTGTFLVDNSSV 254

Query: 306 -YERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHSYRLSEWT 364
            +++  D E +R++GPL  D  V  R       +   T Q+   +  +H+   +R +++ 
Sbjct: 255 DFQKFPDKEILRMAGPLTADFIVKIR----NSGSADSTVQFIFYQPIIHR---WRETDFF 307

Query: 365 PCSVTCGVGYTRRYYECID-QHQRVVEQSQC-YHIEPPRHQALMKQCRKPAC 414
           PCS TCG GY     EC D +  RVV    C Y+ E  + +  +++C    C
Sbjct: 308 PCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPC 359



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 14/138 (10%)

Query: 343 YQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIE 398
           Y+  +     H    +  + WT CS +CG G   R   C+++    H   VE+ +C +  
Sbjct: 365 YKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKCMY-- 422

Query: 399 PPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            P+   + + C    C  W    W+PC+  C   G+ + + R V C+D   ++ +    C
Sbjct: 423 TPK-MPIAQPCNIFDCPKWLAQEWSPCTVTC---GQGL-RYRVVLCID---HRGMHTGGC 474

Query: 459 GQVIKPITTIKCADVPAC 476
               KP    +C     C
Sbjct: 475 SPKTKPHIKEECIVPTPC 492



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 8/60 (13%)

Query: 79  SEWSECSRTCGAGVSTQSRECNN--PEPVNNGNYC------IGDRSRYKVCNTDPCPINE 130
           +++  CS TCG G    S EC +     V    YC      I  + + + CN DPCP ++
Sbjct: 304 TDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPASD 363


>AY358327-1|AAQ88693.1|  525|Homo sapiens ADAMTSL1 protein.
          Length = 525

 Score =  194 bits (473), Expect = 6e-49
 Identities = 119/352 (33%), Positives = 173/352 (49%), Gaps = 24/352 (6%)

Query: 67  SPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           S   RDG W  W  WSECSRTCG G S   R C + +       C G   RY+ C+   C
Sbjct: 28  SEEDRDGLWDAWGPWSECSRTCGGGASYSLRRCLSSKS------CEGRNIRYRTCSNVDC 81

Query: 127 PINEPSFREVQCSRHNNMPYKNETIDEWVPYF-DQDKPCELQCVPRDGTDVEMLGGFVAD 185
           P     FR  QCS HN++ +  +   EW+P   D D PC L+C  +  T V  L   V D
Sbjct: 82  PPEAGDFRAQQCSAHNDVKHHGQFY-EWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLD 140

Query: 186 GTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTR 245
           GT C     S DMCISG+C  VGCD  + S V+ED CGVC GDG+ C+ V+G Y    + 
Sbjct: 141 GTRCYTE--SLDMCISGLCQIVGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSA 198

Query: 246 QSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYFVAGAQAI 305
                 V  +P GSR++++  K     Y+   + +  +    G  + + T  F+    ++
Sbjct: 199 TKSDDTVVALPYGSRHIRLVLKGPDHLYLETKTLQGTK----GENSLSSTGTFLVDNSSV 254

Query: 306 -YERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKHSYRLSEWT 364
            +++  D E +R++GPL  D  V  R       +   T Q+   +  +H+   +R +++ 
Sbjct: 255 DFQKFPDKEILRMAGPLTADFIVKIR----NSGSADSTVQFIFYQPIIHR---WRETDFF 307

Query: 365 PCSVTCGVGYTRRYYECID-QHQRVVEQSQC-YHIEPPRHQALMKQCRKPAC 414
           PCS TCG GY     EC D +  RVV    C Y+ E  + +  +++C    C
Sbjct: 308 PCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPC 359



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 14/138 (10%)

Query: 343 YQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIE 398
           Y+  +     H    +  + WT CS +CG G   R   C+++    H   VE+ +C +  
Sbjct: 365 YKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKCMY-- 422

Query: 399 PPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            P+   + + C    C  W    W+PC+  C   G+ + + R V C+D   ++ +    C
Sbjct: 423 TPK-MPIAQPCNIFDCPKWLAQEWSPCTVTC---GQGL-RYRVVLCID---HRGMHTGGC 474

Query: 459 GQVIKPITTIKCADVPAC 476
               KP    +C     C
Sbjct: 475 SPKTKPHIKEECIVPTPC 492



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 8/60 (13%)

Query: 79  SEWSECSRTCGAGVSTQSRECNN--PEPVNNGNYC------IGDRSRYKVCNTDPCPINE 130
           +++  CS TCG G    S EC +     V    YC      I  + + + CN DPCP ++
Sbjct: 304 TDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPASD 363


>AY358118-1|AAQ88485.1| 1097|Homo sapiens ADAMTS13 protein.
          Length = 1097

 Score =  187 bits (455), Expect = 9e-47
 Identities = 144/454 (31%), Positives = 202/454 (44%), Gaps = 45/454 (9%)

Query: 25  LCEHLWCLVDNV----CTTMMRPAAPGTTCGPDMWCQNQTC---VARTPSPAPRDGGWGP 77
           +C+ L C  D +    C+ ++ P   GT CG + WC    C   V  TP  A   G W  
Sbjct: 1   MCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEKWCSKGRCRSLVELTPIAAVH-GRWSS 59

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQ 137
           W   S CSR+CG GV T+ R+CNNP P   G  C+G   + ++CNT  C   +  F   Q
Sbjct: 60  WGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSEQ 119

Query: 138 CSRHNNMPYKNE----TIDEW---VPYFDQDKPCELQCVPRDGTDVEMLGGFVADGTPCR 190
           C+R +  P ++     +   W   VP+   D  C   C     + +   G    DGT C 
Sbjct: 120 CARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCM 179

Query: 191 ----QAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTRQ 246
               +  G+  +C+SG C   GCD  +DS    D C VCGGD + C   +G +T G  R+
Sbjct: 180 PSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE 239

Query: 247 -SGFSEV-----AIIPAGSRNVKIQEKVS-PGNYISIGSTK-SRRMFLNGARNATLTEYF 298
              F  V     ++  A  R +     V   G Y+  G    S              EY 
Sbjct: 240 YVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRYVVAGKMSISPNTTYPSLLEDGRVEYR 299

Query: 299 VAGAQAIYERDRDWEKVRISGPLAE--DIKVYQRIFR--GRHRNPGVTYQYTVDKQRLHK 354
           VA  +   +R    E++RI GPL E  DI+VY+R     G    P +T+ Y   K R   
Sbjct: 300 VALTE---DRLPRLEEIRIWGPLQEDADIQVYRRYGEEYGNLTRPDITFTYFQPKPR--- 353

Query: 355 KHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQRVVEQSQCYHIEPPRHQALMKQC-RKP 412
           +     +   PCSV+CG G     Y C+DQ  + +VE  QC   + P   A  + C  +P
Sbjct: 354 QAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQP--PAWPEACVLEP 411

Query: 413 ACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
              +W VG + PCS  C   G  + +ER V CV+
Sbjct: 412 CPPYWAVGDFGPCSASC---GGGL-RERPVRCVE 441



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 365 PCSVTCGVGYTRRYYECI--DQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVH-WWVG 420
           PCS +CG+G  RR   C+  DQ Q V V+++ C  +  P        C    C + W VG
Sbjct: 693 PCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASV---PCLIADCTYRWHVG 749

Query: 421 AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            W  CS  C   G+ + + R   C+       V    C  + KP+T   C
Sbjct: 750 TWMECSVSC---GDGIQRRRDT-CLGPQAQAPVPADFCQHLPKPVTVRGC 795



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPP 400
           + + +  W  CSV+CG G  RR   C+  Q Q  V    C H+  P
Sbjct: 744 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKP 789



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 363 WTP----CSVTCGVGYTRRYYECIDQHQRV-VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
           WTP    CSV+CG G     + C+D   RV V++  C     P  +   + C+   C   
Sbjct: 567 WTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSR--REVCQAVPCPAR 624

Query: 418 WVGAWNPCSKLCHMPGEEVTKERSVYCV----DKVMNKVVDDSECGQVIKPITTIKCADV 473
           W      CS  C   G  V + R +YC     +    +++ D++C  + +P     C+  
Sbjct: 625 WQYKLAACSVSC---GRGVVR-RILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLE 680

Query: 474 P 474
           P
Sbjct: 681 P 681


>BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.
          Length = 1509

 Score =  185 bits (451), Expect = 3e-46
 Identities = 75/179 (41%), Positives = 103/179 (57%), Gaps = 2/179 (1%)

Query: 1   MFDAASQCHLQFGAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQT 60
           ++D   QC LQ+G  A  C ++  +C+ LWC V   C + +  AA GT CG   WC    
Sbjct: 471 IYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTQCGEKKWCMAGK 530

Query: 61  CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
           C+     P    GGWG WS WS CSRTCGAGV +  R CNNPEP   G YC G+R RY++
Sbjct: 531 CITVGKKPESIPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRL 590

Query: 121 CNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEML 179
           CN  PC    P+FR++QCS  + +PYKNE +  W P F+     ++  +P+   D+ ++
Sbjct: 591 CNVHPCRSEAPTFRQMQCSEFDTVPYKNE-LYHWFPIFNPGY-VDIGLIPKGARDIRVM 647



 Score =  129 bits (312), Expect = 2e-29
 Identities = 71/232 (30%), Positives = 122/232 (52%), Gaps = 17/232 (7%)

Query: 248 GFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLT-EYFVAGAQAIY 306
           G+ ++ +IP G+R++++ E    GN+++I S    + +LNG         Y +AG    Y
Sbjct: 630 GYVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQY 689

Query: 307 ERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRL-----HKKHSYRLS 361
           +R  D EK+  +GP  E + + Q +F  +  NPG+ Y+YT+ K  L      + + ++  
Sbjct: 690 DRKGDLEKLMATGPTNESVWI-QLLF--QVTNPGIKYEYTIQKDGLDNDVEQQMYFWQYG 746

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVG 420
            WT CSVTCG G  R+   CI + + +V+ + C     P  +   K+C + AC   WW G
Sbjct: 747 HWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGR--QKKCHEKACPPRWWAG 804

Query: 421 AWNPCSKLCHMPGEEVTKERSVYCVDKVMN--KVVDDSECGQVIKPITTIKC 470
            W  CS  C   GE   K+R+V C+  +++  + +  ++C  ++KP T + C
Sbjct: 805 EWEACSATCGPHGE---KKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSC 853



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 36/124 (29%), Positives = 51/124 (41%), Gaps = 14/124 (11%)

Query: 353  HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKP 412
            H    + +  W+ CS TCG+G   R  EC  Q       S C  I+ P      K+C   
Sbjct: 1227 HGSAHWIVGNWSECSTTCGLGAYWRRVECSTQ-----MDSDCAAIQRPDP---AKRCHLR 1278

Query: 413  ACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQV--IKPITTIKC 470
             C  W VG W+ CS+ C        K R + CVD   ++ +    C  +  I P  ++ C
Sbjct: 1279 PCAGWKVGNWSKCSRNC----SGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSC 1334

Query: 471  ADVP 474
               P
Sbjct: 1335 NPEP 1338



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 10/90 (11%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYECIDQHQ-RVVEQSQCYHIE--PPRHQALMKQCRKPAC 414
            +++  W+ CS  C  G+  R  +C+D    R +    C  +   PP    L   C    C
Sbjct: 1283 WKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPP---PLSMSCNPEPC 1339

Query: 415  VHWWVGAWNPCSKLCHMPGEEVTKERSVYC 444
              W V  W+ CS+ C   G  V +ER V+C
Sbjct: 1340 EAWQVEPWSQCSRSC---GGGV-QERGVFC 1365



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 15/102 (14%)

Query: 357  SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
            ++++  W+ CS +CG G   R   C            C   + P        C +  C H
Sbjct: 1341 AWQVEPWSQCSRSCGGGVQERGVFC--------PGGLCDWTKRPTSTM---SCNEHLCCH 1389

Query: 417  WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            W  G W+ CS  C   G    K R+V CV    NK  D  +C
Sbjct: 1390 WATGNWDLCSTSC---GGGFQK-RTVQCVPSEGNKTEDQDQC 1427



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 7/73 (9%)

Query: 362 EWTPCSVTCGV-GYTRRYYECID---QHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH- 416
           EW  CS TCG  G  +R   CI      ++ +  + C H+  P+   L+   R   C   
Sbjct: 805 EWEACSATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPK--TLLSCNRDILCPSD 862

Query: 417 WWVGAWNPCSKLC 429
           W VG W+ CS  C
Sbjct: 863 WTVGNWSECSVSC 875



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 2/53 (3%)

Query: 363  WTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
            W  CS +CG G+ +R  +C+  +  +  +Q QC     PR     K+C + AC
Sbjct: 1395 WDLCSTSCGGGFQKRTVQCVPSEGNKTEDQDQCLCDHKPRPPE-FKKCNQQAC 1446



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 16/54 (29%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 78  WSEWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCIGD---RSRYKVCNTDPCP 127
           +  W+ECS TCG G+  Q+  C      +    +C  +     R K C+   CP
Sbjct: 745 YGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGRQKKCHEKACP 798



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 53/193 (27%), Positives = 72/193 (37%), Gaps = 42/193 (21%)

Query: 81   WSECSRTCGAGVSTQSRECN-----------NPEPVNNGNY--CIGDRSRYKVCNTDPCP 127
            WSECS TCG G   +  EC+            P+P    +   C G    +KV N   C 
Sbjct: 1237 WSECSTTCGLGAYWRRVECSTQMDSDCAAIQRPDPAKRCHLRPCAG----WKVGNWSKCS 1292

Query: 128  INEP---SFREVQC--SR-HNNM-PYKNETIDEWVPYFDQD---KPCEL-------QCVP 170
             N       RE+QC  SR H N+ P+  + +    P        +PCE        QC  
Sbjct: 1293 RNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEPCEAWQVEPWSQCSR 1352

Query: 171  RDGTDVEMLGGFVADG-TPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDG 229
              G  V+  G F   G     +   S   C   +C    C W   +    D C    G G
Sbjct: 1353 SCGGGVQERGVFCPGGLCDWTKRPTSTMSCNEHLC----CHWATGN---WDLCSTSCGGG 1405

Query: 230  TACKTVQGIYTKG 242
               +TVQ + ++G
Sbjct: 1406 FQKRTVQCVPSEG 1418



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 14/26 (53%), Positives = 17/26 (65%), Gaps = 2/26 (7%)

Query: 81  WSECSRTCGAGVSTQSREC--NNPEP 104
           WSECS +CG GV  +S  C  N+ EP
Sbjct: 868 WSECSVSCGGGVRIRSVTCAKNHDEP 893


>AK092324-1|BAC03862.1|  296|Homo sapiens protein ( Homo sapiens
           cDNA FLJ35005 fis, clone OCBBF2012001, weakly similar to
           Homo sapiens zinc metalloprotease ADAMTS6 (ADAMTS6)
           mRNA. ).
          Length = 296

 Score =  167 bits (406), Expect = 7e-41
 Identities = 88/229 (38%), Positives = 118/229 (51%), Gaps = 11/229 (4%)

Query: 65  TPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD 124
           T S   +DG W  W +WS+CSRTCG G S   R C        G  C G   RYK C+  
Sbjct: 68  TRSDEDKDGNWDAWGDWSDCSRTCGGGASYSLRRCLT------GRNCEGQNIRYKTCSNH 121

Query: 125 PCPINEPSFREVQCSRHNNMPYKNETIDEWVP-YFDQDKPCELQCVPRDGTDVEMLGGFV 183
            CP +   FR  QCS +N++ Y+     EW+P Y D   PC L+C  +    V  L   V
Sbjct: 122 DCPPDAEDFRAQQCSAYNDVQYQGHYY-EWLPRYNDPAAPCALKCHAQGQNLVVELAPKV 180

Query: 184 ADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGT 243
            DGT C     S DMCISG+C  VGCD  + S+ +ED CGVC GDG+ C+ V+G      
Sbjct: 181 LDGTRCNT--DSLDMCISGICQAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHV 238

Query: 244 TRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNA 292
           + +     V  +P GSR+V+I  K  P +  S   T++ R++     N+
Sbjct: 239 SPEKREENVIAVPLGSRSVRITVK-GPAHLSSAADTQANRVWSGPPANS 286


>BX649571-2|CAI18773.1|  951|Homo sapiens ADAMTS-like 2 protein.
          Length = 951

 Score =  166 bits (404), Expect = 1e-40
 Identities = 95/289 (32%), Positives = 144/289 (49%), Gaps = 24/289 (8%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSREC----NNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           WG W++W+ CSR+CG GV++Q R C        P      C G   RY++C    CP + 
Sbjct: 50  WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 109

Query: 131 PSFREVQCSRHNNMPYKNETIDEWVPYFDQD------KPCELQCVPRDGTDVEMLGGFVA 184
            SFRE QC   N+  Y   T  +W P +  D      KPC+L C   DG    M+     
Sbjct: 110 RSFREEQCVSFNSHVYNGRT-HQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPA--R 166

Query: 185 DGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTT 244
           DGT C+     R +C+SG C  +GCD ++ S    D CG+C GDG++C  V G Y KG  
Sbjct: 167 DGTSCKLT-DLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNA 225

Query: 245 RQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF-VAGAQ 303
              G+S V  IPAG+R+++I E+    + +++ + ++   F NG       + F +AG  
Sbjct: 226 -HLGYSLVTHIPAGARDIQIVERKKSADVLAL-ADEAGYYFFNGNYKVDSPKNFNIAGTV 283

Query: 304 AIYERDRD-----WEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTV 347
             Y R  D      E +   GP  + + V   ++    ++P +T++YT+
Sbjct: 284 VKYRRPMDVYETGIEYIVAQGPTNQGLNV--MVWNQNGKSPSITFEYTL 330



 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 12/121 (9%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPR--HQALMKQCRKPACV 415
           + +S+W PCS +CG G T R+  C     RVV +SQC     P   H    K C  PA  
Sbjct: 741 WTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNC--PA-- 796

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS--ECGQVIKPITTIKCADV 473
           HW    W  C+  C   G  V K+R V C++    K    S  ECG   KP     C + 
Sbjct: 797 HWLAQDWERCNTTC---GRGV-KKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFER 852

Query: 474 P 474
           P
Sbjct: 853 P 853



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/122 (27%), Positives = 45/122 (36%), Gaps = 16/122 (13%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           +  S W+ CS TCG GY  R   C           V    C   E  R +   K CR PA
Sbjct: 626 WETSSWSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEE-RKTCRNPA 684

Query: 414 C-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
           C   W +  W+ C+  C   GE     R + C +       D+  C    +P+    C  
Sbjct: 685 CGPQWEMSEWSECTAKC---GERSVVTRDIRCSE-------DEKLCDPNTRPVGEKNCTG 734

Query: 473 VP 474
            P
Sbjct: 735 PP 736



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 358 YRLSEWTPCSVTCGV-GYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           + +SEW+ C+  CG      R   C +      ++  C   +P       K C  P C  
Sbjct: 689 WEMSEWSECTAKCGERSVVTRDIRCSE------DEKLC---DPNTRPVGEKNCTGPPCDR 739

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
            W V  W PCS  C   G  +   R VYC      +VV +S+C    KP+    C D
Sbjct: 740 QWTVSDWGPCSGSCGQ-GRTI---RHVYCKTS-DGRVVPESQCQMETKPLAIHPCGD 791



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 15/128 (11%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC- 414
           + ++LS   PCS TC  G    Y  C+      V+ S C  +  P  + + + C    C 
Sbjct: 566 YRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRP--EPVHEFCAGRECQ 623

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS------ECGQVIKPITTI 468
             W   +W+ CS+ C   GE   + R V C  K+++   D S      E  + ++P    
Sbjct: 624 PRWETSSWSECSRTC---GEGY-QFRVVRCW-KMLSPGFDSSVYSDLCEAAEAVRPEERK 678

Query: 469 KCADVPAC 476
            C + PAC
Sbjct: 679 TCRN-PAC 685



 Score = 40.3 bits (90), Expect = 0.014
 Identities = 17/53 (32%), Positives = 25/53 (47%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEP 131
           S WSEC++TCG GV  +  +C     +  G   +      + C+  PCP   P
Sbjct: 860 SPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPP 912



 Score = 38.3 bits (85), Expect = 0.058
 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 15/118 (12%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQ---RVVEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
           +W  C+ TCG G  +R   C++      +     +C   + P  ++    C +  C  W+
Sbjct: 802 DWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEEST---CFERPCFKWY 858

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
              W+ C+K C +      + R V C       +V    C  ++KP+    C D+  C
Sbjct: 859 TSPWSECTKTCGVG----VRMRDVKCYQG--TDIV--RGCDPLVKPVGRQAC-DLQPC 907



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S WSECSRTCG G   +   C
Sbjct: 629 SSWSECSRTCGEGYQFRVVRC 649



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 12/72 (16%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSRECNNPEPVNNGN-YCIGD 114
           + +TC  R P+  P+   W   SEWSEC+  CG   V T+   C+  E + + N   +G+
Sbjct: 676 ERKTC--RNPACGPQ---W-EMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE 729

Query: 115 RSRYKVCNTDPC 126
           ++    C   PC
Sbjct: 730 KN----CTGPPC 737



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/29 (37%), Positives = 18/29 (62%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVV 389
           ++WT CS +CG G T +   C+ Q ++ V
Sbjct: 54  TKWTACSRSCGGGVTSQERHCLQQRRKSV 82


>BX649571-1|CAM26559.1| 1060|Homo sapiens ADAMTS-like 2 protein.
          Length = 1060

 Score =  166 bits (404), Expect = 1e-40
 Identities = 95/289 (32%), Positives = 144/289 (49%), Gaps = 24/289 (8%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSREC----NNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           WG W++W+ CSR+CG GV++Q R C        P      C G   RY++C    CP + 
Sbjct: 159 WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 218

Query: 131 PSFREVQCSRHNNMPYKNETIDEWVPYFDQD------KPCELQCVPRDGTDVEMLGGFVA 184
            SFRE QC   N+  Y   T  +W P +  D      KPC+L C   DG    M+     
Sbjct: 219 RSFREEQCVSFNSHVYNGRT-HQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPA--R 275

Query: 185 DGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTT 244
           DGT C+     R +C+SG C  +GCD ++ S    D CG+C GDG++C  V G Y KG  
Sbjct: 276 DGTSCKLT-DLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNA 334

Query: 245 RQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF-VAGAQ 303
              G+S V  IPAG+R+++I E+    + +++ + ++   F NG       + F +AG  
Sbjct: 335 -HLGYSLVTHIPAGARDIQIVERKKSADVLAL-ADEAGYYFFNGNYKVDSPKNFNIAGTV 392

Query: 304 AIYERDRD-----WEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTV 347
             Y R  D      E +   GP  + + V   ++    ++P +T++YT+
Sbjct: 393 VKYRRPMDVYETGIEYIVAQGPTNQGLNV--MVWNQNGKSPSITFEYTL 439



 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 12/121 (9%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPR--HQALMKQCRKPACV 415
           + +S+W PCS +CG G T R+  C     RVV +SQC     P   H    K C  PA  
Sbjct: 850 WTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNC--PA-- 905

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS--ECGQVIKPITTIKCADV 473
           HW    W  C+  C   G  V K+R V C++    K    S  ECG   KP     C + 
Sbjct: 906 HWLAQDWERCNTTC---GRGV-KKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFER 961

Query: 474 P 474
           P
Sbjct: 962 P 962



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/122 (27%), Positives = 45/122 (36%), Gaps = 16/122 (13%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           +  S W+ CS TCG GY  R   C           V    C   E  R +   K CR PA
Sbjct: 735 WETSSWSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEE-RKTCRNPA 793

Query: 414 C-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
           C   W +  W+ C+  C   GE     R + C +       D+  C    +P+    C  
Sbjct: 794 CGPQWEMSEWSECTAKC---GERSVVTRDIRCSE-------DEKLCDPNTRPVGEKNCTG 843

Query: 473 VP 474
            P
Sbjct: 844 PP 845



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 358 YRLSEWTPCSVTCGV-GYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           + +SEW+ C+  CG      R   C +      ++  C   +P       K C  P C  
Sbjct: 798 WEMSEWSECTAKCGERSVVTRDIRCSE------DEKLC---DPNTRPVGEKNCTGPPCDR 848

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
            W V  W PCS  C   G  +   R VYC      +VV +S+C    KP+    C D
Sbjct: 849 QWTVSDWGPCSGSCGQ-GRTI---RHVYCKTS-DGRVVPESQCQMETKPLAIHPCGD 900



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 15/128 (11%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC- 414
           + ++LS   PCS TC  G    Y  C+      V+ S C  +  P  + + + C    C 
Sbjct: 675 YRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRP--EPVHEFCAGRECQ 732

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS------ECGQVIKPITTI 468
             W   +W+ CS+ C   GE   + R V C  K+++   D S      E  + ++P    
Sbjct: 733 PRWETSSWSECSRTC---GEGY-QFRVVRCW-KMLSPGFDSSVYSDLCEAAEAVRPEERK 787

Query: 469 KCADVPAC 476
            C + PAC
Sbjct: 788 TCRN-PAC 794



 Score = 40.3 bits (90), Expect = 0.014
 Identities = 17/53 (32%), Positives = 25/53 (47%)

Query: 79   SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEP 131
            S WSEC++TCG GV  +  +C     +  G   +      + C+  PCP   P
Sbjct: 969  SPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPP 1021



 Score = 38.3 bits (85), Expect = 0.058
 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 15/118 (12%)

Query: 362  EWTPCSVTCGVGYTRRYYECIDQHQ---RVVEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
            +W  C+ TCG G  +R   C++      +     +C   + P  ++    C +  C  W+
Sbjct: 911  DWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEEST---CFERPCFKWY 967

Query: 419  VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
               W+ C+K C +      + R V C       +V    C  ++KP+    C D+  C
Sbjct: 968  TSPWSECTKTCGVG----VRMRDVKCYQG--TDIV--RGCDPLVKPVGRQAC-DLQPC 1016



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S WSECSRTCG G   +   C
Sbjct: 738 SSWSECSRTCGEGYQFRVVRC 758



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 12/72 (16%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSRECNNPEPVNNGN-YCIGD 114
           + +TC  R P+  P+   W   SEWSEC+  CG   V T+   C+  E + + N   +G+
Sbjct: 785 ERKTC--RNPACGPQ---W-EMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE 838

Query: 115 RSRYKVCNTDPC 126
           ++    C   PC
Sbjct: 839 KN----CTGPPC 846



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/29 (37%), Positives = 18/29 (62%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVV 389
           ++WT CS +CG G T +   C+ Q ++ V
Sbjct: 163 TKWTACSRSCGGGVTSQERHCLQQRRKSV 191


>BX629352-2|CAI23592.1|  951|Homo sapiens ADAMTS-like 2 protein.
          Length = 951

 Score =  166 bits (404), Expect = 1e-40
 Identities = 95/289 (32%), Positives = 144/289 (49%), Gaps = 24/289 (8%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSREC----NNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           WG W++W+ CSR+CG GV++Q R C        P      C G   RY++C    CP + 
Sbjct: 50  WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 109

Query: 131 PSFREVQCSRHNNMPYKNETIDEWVPYFDQD------KPCELQCVPRDGTDVEMLGGFVA 184
            SFRE QC   N+  Y   T  +W P +  D      KPC+L C   DG    M+     
Sbjct: 110 RSFREEQCVSFNSHVYNGRT-HQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPA--R 166

Query: 185 DGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTT 244
           DGT C+     R +C+SG C  +GCD ++ S    D CG+C GDG++C  V G Y KG  
Sbjct: 167 DGTSCKLT-DLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNA 225

Query: 245 RQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF-VAGAQ 303
              G+S V  IPAG+R+++I E+    + +++ + ++   F NG       + F +AG  
Sbjct: 226 -HLGYSLVTHIPAGARDIQIVERKKSADVLAL-ADEAGYYFFNGNYKVDSPKNFNIAGTV 283

Query: 304 AIYERDRD-----WEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTV 347
             Y R  D      E +   GP  + + V   ++    ++P +T++YT+
Sbjct: 284 VKYRRPMDVYETGIEYIVAQGPTNQGLNV--MVWNQNGKSPSITFEYTL 330



 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 12/121 (9%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPR--HQALMKQCRKPACV 415
           + +S+W PCS +CG G T R+  C     RVV +SQC     P   H    K C  PA  
Sbjct: 741 WTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNC--PA-- 796

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS--ECGQVIKPITTIKCADV 473
           HW    W  C+  C   G  V K+R V C++    K    S  ECG   KP     C + 
Sbjct: 797 HWLAQDWERCNTTC---GRGV-KKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFER 852

Query: 474 P 474
           P
Sbjct: 853 P 853



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/122 (27%), Positives = 45/122 (36%), Gaps = 16/122 (13%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           +  S W+ CS TCG GY  R   C           V    C   E  R +   K CR PA
Sbjct: 626 WETSSWSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEE-RKTCRNPA 684

Query: 414 C-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
           C   W +  W+ C+  C   GE     R + C +       D+  C    +P+    C  
Sbjct: 685 CGPQWEMSEWSECTAKC---GERSVVTRDIRCSE-------DEKLCDPNTRPVGEKNCTG 734

Query: 473 VP 474
            P
Sbjct: 735 PP 736



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 358 YRLSEWTPCSVTCGV-GYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           + +SEW+ C+  CG      R   C +      ++  C   +P       K C  P C  
Sbjct: 689 WEMSEWSECTAKCGERSVVTRDIRCSE------DEKLC---DPNTRPVGEKNCTGPPCDR 739

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
            W V  W PCS  C   G  +   R VYC      +VV +S+C    KP+    C D
Sbjct: 740 QWTVSDWGPCSGSCGQ-GRTI---RHVYCKTS-DGRVVPESQCQMETKPLAIHPCGD 791



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 15/128 (11%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC- 414
           + ++LS   PCS TC  G    Y  C+      V+ S C  +  P  + + + C    C 
Sbjct: 566 YRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRP--EPVHEFCAGRECQ 623

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS------ECGQVIKPITTI 468
             W   +W+ CS+ C   GE   + R V C  K+++   D S      E  + ++P    
Sbjct: 624 PRWETSSWSECSRTC---GEGY-QFRVVRCW-KMLSPGFDSSVYSDLCEAAEAVRPEERK 678

Query: 469 KCADVPAC 476
            C + PAC
Sbjct: 679 TCRN-PAC 685



 Score = 40.3 bits (90), Expect = 0.014
 Identities = 17/53 (32%), Positives = 25/53 (47%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEP 131
           S WSEC++TCG GV  +  +C     +  G   +      + C+  PCP   P
Sbjct: 860 SPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPP 912



 Score = 38.3 bits (85), Expect = 0.058
 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 15/118 (12%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQ---RVVEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
           +W  C+ TCG G  +R   C++      +     +C   + P  ++    C +  C  W+
Sbjct: 802 DWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEEST---CFERPCFKWY 858

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
              W+ C+K C +      + R V C       +V    C  ++KP+    C D+  C
Sbjct: 859 TSPWSECTKTCGVG----VRMRDVKCYQG--TDIV--RGCDPLVKPVGRQAC-DLQPC 907



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S WSECSRTCG G   +   C
Sbjct: 629 SSWSECSRTCGEGYQFRVVRC 649



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 12/72 (16%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSRECNNPEPVNNGN-YCIGD 114
           + +TC  R P+  P+   W   SEWSEC+  CG   V T+   C+  E + + N   +G+
Sbjct: 676 ERKTC--RNPACGPQ---W-EMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE 729

Query: 115 RSRYKVCNTDPC 126
           ++    C   PC
Sbjct: 730 KN----CTGPPC 737



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/29 (37%), Positives = 18/29 (62%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVV 389
           ++WT CS +CG G T +   C+ Q ++ V
Sbjct: 54  TKWTACSRSCGGGVTSQERHCLQQRRKSV 82


>BX629352-1|CAM28356.1| 1060|Homo sapiens ADAMTS-like 2 protein.
          Length = 1060

 Score =  166 bits (404), Expect = 1e-40
 Identities = 95/289 (32%), Positives = 144/289 (49%), Gaps = 24/289 (8%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSREC----NNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           WG W++W+ CSR+CG GV++Q R C        P      C G   RY++C    CP + 
Sbjct: 159 WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 218

Query: 131 PSFREVQCSRHNNMPYKNETIDEWVPYFDQD------KPCELQCVPRDGTDVEMLGGFVA 184
            SFRE QC   N+  Y   T  +W P +  D      KPC+L C   DG    M+     
Sbjct: 219 RSFREEQCVSFNSHVYNGRT-HQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPA--R 275

Query: 185 DGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTT 244
           DGT C+     R +C+SG C  +GCD ++ S    D CG+C GDG++C  V G Y KG  
Sbjct: 276 DGTSCKLT-DLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNA 334

Query: 245 RQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF-VAGAQ 303
              G+S V  IPAG+R+++I E+    + +++ + ++   F NG       + F +AG  
Sbjct: 335 -HLGYSLVTHIPAGARDIQIVERKKSADVLAL-ADEAGYYFFNGNYKVDSPKNFNIAGTV 392

Query: 304 AIYERDRD-----WEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTV 347
             Y R  D      E +   GP  + + V   ++    ++P +T++YT+
Sbjct: 393 VKYRRPMDVYETGIEYIVAQGPTNQGLNV--MVWNQNGKSPSITFEYTL 439



 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 12/121 (9%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPR--HQALMKQCRKPACV 415
           + +S+W PCS +CG G T R+  C     RVV +SQC     P   H    K C  PA  
Sbjct: 850 WTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNC--PA-- 905

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS--ECGQVIKPITTIKCADV 473
           HW    W  C+  C   G  V K+R V C++    K    S  ECG   KP     C + 
Sbjct: 906 HWLAQDWERCNTTC---GRGV-KKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFER 961

Query: 474 P 474
           P
Sbjct: 962 P 962



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/122 (27%), Positives = 45/122 (36%), Gaps = 16/122 (13%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           +  S W+ CS TCG GY  R   C           V    C   E  R +   K CR PA
Sbjct: 735 WETSSWSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEE-RKTCRNPA 793

Query: 414 C-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
           C   W +  W+ C+  C   GE     R + C +       D+  C    +P+    C  
Sbjct: 794 CGPQWEMSEWSECTAKC---GERSVVTRDIRCSE-------DEKLCDPNTRPVGEKNCTG 843

Query: 473 VP 474
            P
Sbjct: 844 PP 845



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 358 YRLSEWTPCSVTCGV-GYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           + +SEW+ C+  CG      R   C +      ++  C   +P       K C  P C  
Sbjct: 798 WEMSEWSECTAKCGERSVVTRDIRCSE------DEKLC---DPNTRPVGEKNCTGPPCDR 848

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
            W V  W PCS  C   G  +   R VYC      +VV +S+C    KP+    C D
Sbjct: 849 QWTVSDWGPCSGSCGQ-GRTI---RHVYCKTS-DGRVVPESQCQMETKPLAIHPCGD 900



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 15/128 (11%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC- 414
           + ++LS   PCS TC  G    Y  C+      V+ S C  +  P  + + + C    C 
Sbjct: 675 YRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRP--EPVHEFCAGRECQ 732

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS------ECGQVIKPITTI 468
             W   +W+ CS+ C   GE   + R V C  K+++   D S      E  + ++P    
Sbjct: 733 PRWETSSWSECSRTC---GEGY-QFRVVRCW-KMLSPGFDSSVYSDLCEAAEAVRPEERK 787

Query: 469 KCADVPAC 476
            C + PAC
Sbjct: 788 TCRN-PAC 794



 Score = 40.3 bits (90), Expect = 0.014
 Identities = 17/53 (32%), Positives = 25/53 (47%)

Query: 79   SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEP 131
            S WSEC++TCG GV  +  +C     +  G   +      + C+  PCP   P
Sbjct: 969  SPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPP 1021



 Score = 38.3 bits (85), Expect = 0.058
 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 15/118 (12%)

Query: 362  EWTPCSVTCGVGYTRRYYECIDQHQ---RVVEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
            +W  C+ TCG G  +R   C++      +     +C   + P  ++    C +  C  W+
Sbjct: 911  DWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEEST---CFERPCFKWY 967

Query: 419  VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
               W+ C+K C +      + R V C       +V    C  ++KP+    C D+  C
Sbjct: 968  TSPWSECTKTCGVG----VRMRDVKCYQG--TDIV--RGCDPLVKPVGRQAC-DLQPC 1016



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S WSECSRTCG G   +   C
Sbjct: 738 SSWSECSRTCGEGYQFRVVRC 758



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 12/72 (16%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSRECNNPEPVNNGN-YCIGD 114
           + +TC  R P+  P+   W   SEWSEC+  CG   V T+   C+  E + + N   +G+
Sbjct: 785 ERKTC--RNPACGPQ---W-EMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE 838

Query: 115 RSRYKVCNTDPC 126
           ++    C   PC
Sbjct: 839 KN----CTGPPC 846



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/29 (37%), Positives = 18/29 (62%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVV 389
           ++WT CS +CG G T +   C+ Q ++ V
Sbjct: 163 TKWTACSRSCGGGVTSQERHCLQQRRKSV 191


>BX324209-2|CAI17317.1|  951|Homo sapiens ADAMTS-like 2 protein.
          Length = 951

 Score =  166 bits (404), Expect = 1e-40
 Identities = 95/289 (32%), Positives = 144/289 (49%), Gaps = 24/289 (8%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSREC----NNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           WG W++W+ CSR+CG GV++Q R C        P      C G   RY++C    CP + 
Sbjct: 50  WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 109

Query: 131 PSFREVQCSRHNNMPYKNETIDEWVPYFDQD------KPCELQCVPRDGTDVEMLGGFVA 184
            SFRE QC   N+  Y   T  +W P +  D      KPC+L C   DG    M+     
Sbjct: 110 RSFREEQCVSFNSHVYNGRT-HQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPA--R 166

Query: 185 DGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTT 244
           DGT C+     R +C+SG C  +GCD ++ S    D CG+C GDG++C  V G Y KG  
Sbjct: 167 DGTSCKLT-DLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNA 225

Query: 245 RQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF-VAGAQ 303
              G+S V  IPAG+R+++I E+    + +++ + ++   F NG       + F +AG  
Sbjct: 226 -HLGYSLVTHIPAGARDIQIVERKKSADVLAL-ADEAGYYFFNGNYKVDSPKNFNIAGTV 283

Query: 304 AIYERDRD-----WEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTV 347
             Y R  D      E +   GP  + + V   ++    ++P +T++YT+
Sbjct: 284 VKYRRPMDVYETGIEYIVAQGPTNQGLNV--MVWNQNGKSPSITFEYTL 330



 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 12/121 (9%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPR--HQALMKQCRKPACV 415
           + +S+W PCS +CG G T R+  C     RVV +SQC     P   H    K C  PA  
Sbjct: 741 WTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNC--PA-- 796

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS--ECGQVIKPITTIKCADV 473
           HW    W  C+  C   G  V K+R V C++    K    S  ECG   KP     C + 
Sbjct: 797 HWLAQDWERCNTTC---GRGV-KKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFER 852

Query: 474 P 474
           P
Sbjct: 853 P 853



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/122 (27%), Positives = 45/122 (36%), Gaps = 16/122 (13%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           +  S W+ CS TCG GY  R   C           V    C   E  R +   K CR PA
Sbjct: 626 WETSSWSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEE-RKTCRNPA 684

Query: 414 C-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
           C   W +  W+ C+  C   GE     R + C +       D+  C    +P+    C  
Sbjct: 685 CGPQWEMSEWSECTAKC---GERSVVTRDIRCSE-------DEKLCDPNTRPVGEKNCTG 734

Query: 473 VP 474
            P
Sbjct: 735 PP 736



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 358 YRLSEWTPCSVTCGV-GYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           + +SEW+ C+  CG      R   C +      ++  C   +P       K C  P C  
Sbjct: 689 WEMSEWSECTAKCGERSVVTRDIRCSE------DEKLC---DPNTRPVGEKNCTGPPCDR 739

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
            W V  W PCS  C   G  +   R VYC      +VV +S+C    KP+    C D
Sbjct: 740 QWTVSDWGPCSGSCGQ-GRTI---RHVYCKTS-DGRVVPESQCQMETKPLAIHPCGD 791



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 15/128 (11%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC- 414
           + ++LS   PCS TC  G    Y  C+      V+ S C  +  P  + + + C    C 
Sbjct: 566 YRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRP--EPVHEFCAGRECQ 623

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS------ECGQVIKPITTI 468
             W   +W+ CS+ C   GE   + R V C  K+++   D S      E  + ++P    
Sbjct: 624 PRWETSSWSECSRTC---GEGY-QFRVVRCW-KMLSPGFDSSVYSDLCEAAEAVRPEERK 678

Query: 469 KCADVPAC 476
            C + PAC
Sbjct: 679 TCRN-PAC 685



 Score = 40.3 bits (90), Expect = 0.014
 Identities = 17/53 (32%), Positives = 25/53 (47%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEP 131
           S WSEC++TCG GV  +  +C     +  G   +      + C+  PCP   P
Sbjct: 860 SPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPP 912



 Score = 38.3 bits (85), Expect = 0.058
 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 15/118 (12%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQ---RVVEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
           +W  C+ TCG G  +R   C++      +     +C   + P  ++    C +  C  W+
Sbjct: 802 DWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEEST---CFERPCFKWY 858

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
              W+ C+K C +      + R V C       +V    C  ++KP+    C D+  C
Sbjct: 859 TSPWSECTKTCGVG----VRMRDVKCYQG--TDIV--RGCDPLVKPVGRQAC-DLQPC 907



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S WSECSRTCG G   +   C
Sbjct: 629 SSWSECSRTCGEGYQFRVVRC 649



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 12/72 (16%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSRECNNPEPVNNGN-YCIGD 114
           + +TC  R P+  P+   W   SEWSEC+  CG   V T+   C+  E + + N   +G+
Sbjct: 676 ERKTC--RNPACGPQ---W-EMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE 729

Query: 115 RSRYKVCNTDPC 126
           ++    C   PC
Sbjct: 730 KN----CTGPPC 737



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/29 (37%), Positives = 18/29 (62%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVV 389
           ++WT CS +CG G T +   C+ Q ++ V
Sbjct: 54  TKWTACSRSCGGGVTSQERHCLQQRRKSV 82


>BX324209-1|CAM24586.1| 1060|Homo sapiens ADAMTS-like 2 protein.
          Length = 1060

 Score =  166 bits (404), Expect = 1e-40
 Identities = 95/289 (32%), Positives = 144/289 (49%), Gaps = 24/289 (8%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSREC----NNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           WG W++W+ CSR+CG GV++Q R C        P      C G   RY++C    CP + 
Sbjct: 159 WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 218

Query: 131 PSFREVQCSRHNNMPYKNETIDEWVPYFDQD------KPCELQCVPRDGTDVEMLGGFVA 184
            SFRE QC   N+  Y   T  +W P +  D      KPC+L C   DG    M+     
Sbjct: 219 RSFREEQCVSFNSHVYNGRT-HQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPA--R 275

Query: 185 DGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTT 244
           DGT C+     R +C+SG C  +GCD ++ S    D CG+C GDG++C  V G Y KG  
Sbjct: 276 DGTSCKLT-DLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNA 334

Query: 245 RQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF-VAGAQ 303
              G+S V  IPAG+R+++I E+    + +++ + ++   F NG       + F +AG  
Sbjct: 335 -HLGYSLVTHIPAGARDIQIVERKKSADVLAL-ADEAGYYFFNGNYKVDSPKNFNIAGTV 392

Query: 304 AIYERDRD-----WEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTV 347
             Y R  D      E +   GP  + + V   ++    ++P +T++YT+
Sbjct: 393 VKYRRPMDVYETGIEYIVAQGPTNQGLNV--MVWNQNGKSPSITFEYTL 439



 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 12/121 (9%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPR--HQALMKQCRKPACV 415
           + +S+W PCS +CG G T R+  C     RVV +SQC     P   H    K C  PA  
Sbjct: 850 WTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNC--PA-- 905

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS--ECGQVIKPITTIKCADV 473
           HW    W  C+  C   G  V K+R V C++    K    S  ECG   KP     C + 
Sbjct: 906 HWLAQDWERCNTTC---GRGV-KKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFER 961

Query: 474 P 474
           P
Sbjct: 962 P 962



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/122 (27%), Positives = 45/122 (36%), Gaps = 16/122 (13%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           +  S W+ CS TCG GY  R   C           V    C   E  R +   K CR PA
Sbjct: 735 WETSSWSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEE-RKTCRNPA 793

Query: 414 C-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
           C   W +  W+ C+  C   GE     R + C +       D+  C    +P+    C  
Sbjct: 794 CGPQWEMSEWSECTAKC---GERSVVTRDIRCSE-------DEKLCDPNTRPVGEKNCTG 843

Query: 473 VP 474
            P
Sbjct: 844 PP 845



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 358 YRLSEWTPCSVTCGV-GYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           + +SEW+ C+  CG      R   C +      ++  C   +P       K C  P C  
Sbjct: 798 WEMSEWSECTAKCGERSVVTRDIRCSE------DEKLC---DPNTRPVGEKNCTGPPCDR 848

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
            W V  W PCS  C   G  +   R VYC      +VV +S+C    KP+    C D
Sbjct: 849 QWTVSDWGPCSGSCGQ-GRTI---RHVYCKTS-DGRVVPESQCQMETKPLAIHPCGD 900



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 15/128 (11%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC- 414
           + ++LS   PCS TC  G    Y  C+      V+ S C  +  P  + + + C    C 
Sbjct: 675 YRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRP--EPVHEFCAGRECQ 732

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS------ECGQVIKPITTI 468
             W   +W+ CS+ C   GE   + R V C  K+++   D S      E  + ++P    
Sbjct: 733 PRWETSSWSECSRTC---GEGY-QFRVVRCW-KMLSPGFDSSVYSDLCEAAEAVRPEERK 787

Query: 469 KCADVPAC 476
            C + PAC
Sbjct: 788 TCRN-PAC 794



 Score = 40.3 bits (90), Expect = 0.014
 Identities = 17/53 (32%), Positives = 25/53 (47%)

Query: 79   SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEP 131
            S WSEC++TCG GV  +  +C     +  G   +      + C+  PCP   P
Sbjct: 969  SPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPP 1021



 Score = 38.3 bits (85), Expect = 0.058
 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 15/118 (12%)

Query: 362  EWTPCSVTCGVGYTRRYYECIDQHQ---RVVEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
            +W  C+ TCG G  +R   C++      +     +C   + P  ++    C +  C  W+
Sbjct: 911  DWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEEST---CFERPCFKWY 967

Query: 419  VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
               W+ C+K C +      + R V C       +V    C  ++KP+    C D+  C
Sbjct: 968  TSPWSECTKTCGVG----VRMRDVKCYQG--TDIV--RGCDPLVKPVGRQAC-DLQPC 1016



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S WSECSRTCG G   +   C
Sbjct: 738 SSWSECSRTCGEGYQFRVVRC 758



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 12/72 (16%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSRECNNPEPVNNGN-YCIGD 114
           + +TC  R P+  P+   W   SEWSEC+  CG   V T+   C+  E + + N   +G+
Sbjct: 785 ERKTC--RNPACGPQ---W-EMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE 838

Query: 115 RSRYKVCNTDPC 126
           ++    C   PC
Sbjct: 839 KN----CTGPPC 846



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/29 (37%), Positives = 18/29 (62%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVV 389
           ++WT CS +CG G T +   C+ Q ++ V
Sbjct: 163 TKWTACSRSCGGGVTSQERHCLQQRRKSV 191


>BC050544-1|AAH50544.1|  951|Homo sapiens ADAMTS-like 2 protein.
          Length = 951

 Score =  166 bits (404), Expect = 1e-40
 Identities = 95/289 (32%), Positives = 144/289 (49%), Gaps = 24/289 (8%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSREC----NNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           WG W++W+ CSR+CG GV++Q R C        P      C G   RY++C    CP + 
Sbjct: 50  WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 109

Query: 131 PSFREVQCSRHNNMPYKNETIDEWVPYFDQD------KPCELQCVPRDGTDVEMLGGFVA 184
            SFRE QC   N+  Y   T  +W P +  D      KPC+L C   DG    M+     
Sbjct: 110 RSFREEQCVSFNSHVYNGRT-HQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPA--R 166

Query: 185 DGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTT 244
           DGT C+     R +C+SG C  +GCD ++ S    D CG+C GDG++C  V G Y KG  
Sbjct: 167 DGTSCKLT-DLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNA 225

Query: 245 RQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF-VAGAQ 303
              G+S V  IPAG+R+++I E+    + +++ + ++   F NG       + F +AG  
Sbjct: 226 -HLGYSLVTHIPAGARDIQIVERKKSADVLAL-ADEAGYYFFNGNYKVDSPKNFNIAGTV 283

Query: 304 AIYERDRD-----WEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTV 347
             Y R  D      E +   GP  + + V   ++    ++P +T++YT+
Sbjct: 284 VKYRRPMDVYETGIEYIVAQGPTNQGLNV--MVWNQNGKSPSITFEYTL 330



 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 12/121 (9%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPR--HQALMKQCRKPACV 415
           + +S+W PCS +CG G T R+  C     RVV +SQC     P   H    K C  PA  
Sbjct: 741 WTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNC--PA-- 796

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS--ECGQVIKPITTIKCADV 473
           HW    W  C+  C   G  V K+R V C++    K    S  ECG   KP     C + 
Sbjct: 797 HWLAQDWERCNTTC---GRGV-KKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFER 852

Query: 474 P 474
           P
Sbjct: 853 P 853



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/122 (27%), Positives = 45/122 (36%), Gaps = 16/122 (13%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           +  S W+ CS TCG GY  R   C           V    C   E  R +   K CR PA
Sbjct: 626 WETSSWSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEE-RKTCRNPA 684

Query: 414 C-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
           C   W +  W+ C+  C   GE     R + C +       D+  C    +P+    C  
Sbjct: 685 CGPQWEMSEWSECTAKC---GERSVVTRDIRCSE-------DEKLCDPNTRPVGEKNCTG 734

Query: 473 VP 474
            P
Sbjct: 735 PP 736



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 358 YRLSEWTPCSVTCGV-GYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           + +SEW+ C+  CG      R   C +      ++  C   +P       K C  P C  
Sbjct: 689 WEMSEWSECTAKCGERSVVTRDIRCSE------DEKLC---DPNTRPVGEKNCTGPPCDR 739

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
            W V  W PCS  C   G  +   R VYC      +VV +S+C    KP+    C D
Sbjct: 740 QWTVSDWGPCSGSCGQ-GRTI---RHVYCKTS-DGRVVPESQCQMETKPLAIHPCGD 791



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 15/128 (11%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC- 414
           + ++LS   PCS TC  G    Y  C+      V+ S C  +  P  + + + C    C 
Sbjct: 566 YRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRP--EPVHEFCAGRECQ 623

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS------ECGQVIKPITTI 468
             W   +W+ CS+ C   GE   + R V C  K+++   D S      E  + ++P    
Sbjct: 624 PRWETSSWSECSRTC---GEGY-QFRVVRCW-KMLSPGFDSSVYSDLCEAAEAVRPEERK 678

Query: 469 KCADVPAC 476
            C + PAC
Sbjct: 679 TCRN-PAC 685



 Score = 40.3 bits (90), Expect = 0.014
 Identities = 17/53 (32%), Positives = 25/53 (47%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEP 131
           S WSEC++TCG GV  +  +C     +  G   +      + C+  PCP   P
Sbjct: 860 SPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPP 912



 Score = 38.3 bits (85), Expect = 0.058
 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 15/118 (12%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQ---RVVEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
           +W  C+ TCG G  +R   C++      +     +C   + P  ++    C +  C  W+
Sbjct: 802 DWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEEST---CFERPCFKWY 858

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
              W+ C+K C +      + R V C       +V    C  ++KP+    C D+  C
Sbjct: 859 TSPWSECTKTCGVG----VRMRDVKCYQG--TDIV--RGCDPLVKPVGRQAC-DLQPC 907



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S WSECSRTCG G   +   C
Sbjct: 629 SSWSECSRTCGEGYQFRVVRC 649



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 12/72 (16%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSRECNNPEPVNNGN-YCIGD 114
           + +TC  R P+  P+   W   SEWSEC+  CG   V T+   C+  E + + N   +G+
Sbjct: 676 ERKTC--RNPACGPQ---W-EMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE 729

Query: 115 RSRYKVCNTDPC 126
           ++    C   PC
Sbjct: 730 KN----CTGPPC 737



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 11/29 (37%), Positives = 18/29 (62%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVV 389
           ++WT CS +CG G T +   C+ Q ++ V
Sbjct: 54  TKWTACSRSCGGGVTSQERHCLQQRRKSV 82


>AB011177-1|BAA25531.2| 1031|Homo sapiens KIAA0605 protein protein.
          Length = 1031

 Score =  162 bits (393), Expect = 3e-39
 Identities = 94/289 (32%), Positives = 143/289 (49%), Gaps = 24/289 (8%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSREC----NNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           WG W++W+  SR+CG GV++Q R C        P      C G   RY++C    CP + 
Sbjct: 130 WGEWTKWTAFSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 189

Query: 131 PSFREVQCSRHNNMPYKNETIDEWVPYFDQD------KPCELQCVPRDGTDVEMLGGFVA 184
            SFRE QC   N+  Y   T  +W P +  D      KPC+L C   DG    M+     
Sbjct: 190 RSFREEQCVSFNSHVYNGRT-HQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPA--R 246

Query: 185 DGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTT 244
           DGT C+     R +C+SG C  +GCD ++ S    D CG+C GDG++C  V G Y KG  
Sbjct: 247 DGTSCKLT-DLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNA 305

Query: 245 RQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF-VAGAQ 303
              G+S V  IPAG+R+++I E+    + +++ + ++   F NG       + F +AG  
Sbjct: 306 -HLGYSLVTHIPAGARDIQIVERKKSADVLAL-ADEAGYYFFNGNYKVDSPKNFNIAGTV 363

Query: 304 AIYERDRD-----WEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTV 347
             Y R  D      E +   GP  + + V   ++    ++P +T++YT+
Sbjct: 364 VKYRRPMDVYETGIEYIVAQGPTNQGLNV--MVWNQNGKSPSITFEYTL 410



 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 12/121 (9%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPR--HQALMKQCRKPACV 415
           + +S+W PCS +CG G T R+  C     RVV +SQC     P   H    K C  PA  
Sbjct: 821 WTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNC--PA-- 876

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS--ECGQVIKPITTIKCADV 473
           HW    W  C+  C   G  V K+R V C++    K    S  ECG   KP     C + 
Sbjct: 877 HWLAQDWERCNTTC---GRGV-KKRLVLCMELANGKPQTRSGPECGLAKKPPEESTCFER 932

Query: 474 P 474
           P
Sbjct: 933 P 933



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/122 (27%), Positives = 45/122 (36%), Gaps = 16/122 (13%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           +  S W+ CS TCG GY  R   C           V    C   E  R +   K CR PA
Sbjct: 706 WETSSWSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEE-RKTCRNPA 764

Query: 414 C-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
           C   W +  W+ C+  C   GE     R + C +       D+  C    +P+    C  
Sbjct: 765 CGPQWEMSEWSECTAKC---GERSVVTRDIRCSE-------DEKLCDPNTRPVGEKNCTG 814

Query: 473 VP 474
            P
Sbjct: 815 PP 816



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 358 YRLSEWTPCSVTCGV-GYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           + +SEW+ C+  CG      R   C +      ++  C   +P       K C  P C  
Sbjct: 769 WEMSEWSECTAKCGERSVVTRDIRCSE------DEKLC---DPNTRPVGEKNCTGPPCDR 819

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCAD 472
            W V  W PCS  C   G  +   R VYC      +VV +S+C    KP+    C D
Sbjct: 820 QWTVSDWGPCSGSCGQ-GRTI---RHVYCKTS-DGRVVPESQCQMETKPLAIHPCGD 871



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 15/128 (11%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC- 414
           + ++LS   PCS TC  G    Y  C+      V+ S C  +  P  + + + C    C 
Sbjct: 646 YRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEVDDSYCDALTRP--EPVHEFCAGRECQ 703

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS------ECGQVIKPITTI 468
             W   +W+ CS+ C   GE   + R V C  K+++   D S      E  + ++P    
Sbjct: 704 PRWETSSWSECSRTC---GEGY-QFRVVRCW-KMLSPGFDSSVYSDLCEAAEAVRPEERK 758

Query: 469 KCADVPAC 476
            C + PAC
Sbjct: 759 TCRN-PAC 765



 Score = 40.3 bits (90), Expect = 0.014
 Identities = 17/53 (32%), Positives = 25/53 (47%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEP 131
           S WSEC++TCG GV  +  +C     +  G   +      + C+  PCP   P
Sbjct: 940 SPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPP 992



 Score = 38.3 bits (85), Expect = 0.058
 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 15/118 (12%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQ---RVVEQSQCYHIEPPRHQALMKQCRKPACVHWW 418
           +W  C+ TCG G  +R   C++      +     +C   + P  ++    C +  C  W+
Sbjct: 882 DWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEEST---CFERPCFKWY 938

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
              W+ C+K C +      + R V C       +V    C  ++KP+    C D+  C
Sbjct: 939 TSPWSECTKTCGVG----VRMRDVKCYQG--TDIV--RGCDPLVKPVGRQAC-DLQPC 987



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S WSECSRTCG G   +   C
Sbjct: 709 SSWSECSRTCGEGYQFRVVRC 729



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 12/72 (16%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSRECNNPEPVNNGN-YCIGD 114
           + +TC  R P+  P+   W   SEWSEC+  CG   V T+   C+  E + + N   +G+
Sbjct: 756 ERKTC--RNPACGPQ---W-EMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE 809

Query: 115 RSRYKVCNTDPC 126
           ++    C   PC
Sbjct: 810 KN----CTGPPC 817


>BC040620-1|AAH40620.1|  356|Homo sapiens ADAMTSL5 protein protein.
          Length = 356

 Score =  153 bits (370), Expect = 2e-36
 Identities = 84/282 (29%), Positives = 143/282 (50%), Gaps = 16/282 (5%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPS 132
           G W PW  W+ CS +CG GVS +SR C     +     C GD   Y++C    CP     
Sbjct: 36  GEWTPWVSWTRCSSSCGRGVSVRSRRCLR---LPGEEPCWGDSHEYRLCQLPDCPPGAVP 92

Query: 133 FREVQCSRHNNMPYKN-ETIDEWVPYFDQDKPCELQCVPRDGTDVEMLGGFVADGTPCRQ 191
           FR++QC+ +N  P    +   +WVP+      C+L C+  +G       G V DGT C  
Sbjct: 93  FRDLQCALYNGRPVLGTQKTYQWVPFHGAPNQCDLNCLA-EGHAFYHSFGRVLDGTACSP 151

Query: 192 AIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTRQSGFSE 251
             G++ +C++G C   GCD ++ S   ED CG CGG   +C  VQ ++ +     +G+  
Sbjct: 152 --GAQGVCVAGRCLSAGCDGLLGSGALEDRCGRCGGANDSCLFVQRVF-RDAGAFAGYWN 208

Query: 252 VAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLT-EYFVAGAQAIYERDR 310
           V +IP G+R+++++ +    N++++     R + LNG    +    Y  AG   +Y RD 
Sbjct: 209 VTLIPEGARHIRVEHR--SRNHLALMGGDGRYV-LNGHWVVSPPGTYEAAGTHVVYTRDT 265

Query: 311 -DWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQR 351
              E ++ +GP + D+ +   +   +  NPG+ +++ + ++R
Sbjct: 266 GPQETLQAAGPTSHDLLLQVLL---QEPNPGIEFEFWLPRER 304


>AK131571-1|BAD18703.1|  471|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16825 fis, clone UTERU2036507, weakly  similar
           to ADAM-TS 6 precursor (EC 3.4.24.-). ).
          Length = 471

 Score =  152 bits (369), Expect = 2e-36
 Identities = 84/282 (29%), Positives = 143/282 (50%), Gaps = 16/282 (5%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPS 132
           G W PW  W+ CS +CG GVS +SR C     +     C GD   Y++C    CP     
Sbjct: 36  GEWTPWVSWTRCSSSCGRGVSVRSRRCLR---LPGEEPCWGDSHEYRLCQLPDCPPGAVP 92

Query: 133 FREVQCSRHNNMPYKN-ETIDEWVPYFDQDKPCELQCVPRDGTDVEMLGGFVADGTPCRQ 191
           FR++QC+ +N  P    +   +WVP+      C+L C+  +G       G V DGT C  
Sbjct: 93  FRDLQCALYNGRPVLGTQKTYQWVPFHGAPNQCDLNCLA-EGHAFYHSFGRVLDGTACSP 151

Query: 192 AIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTRQSGFSE 251
             G++ +C++G C   GCD ++ S   ED CG CGG   +C  VQ ++ +     +G+  
Sbjct: 152 --GAQGVCVAGRCLSAGCDGLLGSGALEDRCGRCGGADDSCLFVQRVF-RDAGAFAGYWN 208

Query: 252 VAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLT-EYFVAGAQAIYERDR 310
           V +IP G+R+++++ +    N++++     R + LNG    +    Y  AG   +Y RD 
Sbjct: 209 VTLIPEGARHIRVEHR--SRNHLALMGGDGRYV-LNGHWVVSPPGTYEAAGTHVVYTRDT 265

Query: 311 -DWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQR 351
              E ++ +GP + D+ +   +   +  NPG+ +++ + ++R
Sbjct: 266 GPQETLQAAGPTSHDLLLQVLL---QEPNPGIEFEFWLPRER 304


>AJ011374-1|CAB66157.1|  364|Homo sapiens hypothetical protein
           protein.
          Length = 364

 Score =  147 bits (357), Expect = 6e-35
 Identities = 80/241 (33%), Positives = 113/241 (46%), Gaps = 19/241 (7%)

Query: 24  ELCEHLWCLVDNV----CTTMMRPAAPGTTCGPDMWCQNQTC---VARTPSPAPRDGGWG 76
           ++C+ L C  D +    C+ ++ P   GT CG + WC    C   V  TP  A   G W 
Sbjct: 2   DMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEKWCSKGRCRSLVELTPIAAVH-GRWS 60

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREV 136
            W   S CSR+CG GV T+ R+CNNP P   G  C+G   + ++CNT  C   +  F   
Sbjct: 61  SWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQ 120

Query: 137 QCSRHNNMPYKNE----TIDEW---VPYFDQDKPCELQCVPRDGTDVEMLGGFVADGTPC 189
           QC+R +  P ++     +   W   VP+   D  C   C     + +   G    DGT C
Sbjct: 121 QCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRC 180

Query: 190 R----QAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTR 245
                +  G+  +C+SG C   GCD  +DS    D C VCGGD + C   +G +T G  R
Sbjct: 181 MPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRAR 240

Query: 246 Q 246
           +
Sbjct: 241 E 241


>AK131551-1|BAD18685.1|  577|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16791 fis, clone TBAES2004105, weakly  similar
           to ADAM-TS 6 precursor (EC 3.4.24.-). ).
          Length = 577

 Score =  139 bits (337), Expect = 2e-32
 Identities = 89/273 (32%), Positives = 126/273 (46%), Gaps = 17/273 (6%)

Query: 83  ECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQCSRHN 142
           E S   G G    ++  + P   +    CIG   +YK+CNT+ CP +  S REVQC+ +N
Sbjct: 264 ETSNNHGVGTHGATQSFSQPAR-STAISCIGAYRQYKLCNTNVCPESSRSIREVQCASYN 322

Query: 143 NMPYKNETIDEWVPYFDQ--DKPCELQCVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCI 200
           N P+      EW P+ +   ++ CEL C              V DGTPC Q      +C+
Sbjct: 323 NKPFMGRFY-EWEPFAEVKGNRKCELNCQAMGYRFYVRQAEKVIDGTPCDQ--NGTAICV 379

Query: 201 SGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSR 260
           SG C  +GCD  + SD   D CGVCGGD T C+ V G++    T   G+  V  I  G+ 
Sbjct: 380 SGQCKSIGCDDYLGSDKVVDKCGVCGGDNTGCQVVSGVFKHALT-SLGYHRVVEISEGAT 438

Query: 261 NVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLT-EYFVAGAQAIYERDRD-----WEK 314
            + I E     NY+++ S +S R  +NG        +Y   G    Y+R  +      E 
Sbjct: 439 KINITEMYKSNNYLALRS-RSGRSIINGNWAIDRPGKYEGGGTMFTYKRPNEISSTAGES 497

Query: 315 VRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTV 347
               GP  E + VY      +  NPGV Y+Y +
Sbjct: 498 FLAEGPTNEILDVY---MIHQQPNPGVHYEYVI 527



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 15/27 (55%), Positives = 17/27 (62%)

Query: 73 GGWGPWSEWSECSRTCGAGVSTQSREC 99
          G WG W  WS CSR+C  GV  Q+R C
Sbjct: 54 GVWGAWGPWSACSRSCSGGVMEQTRPC 80


>BX641106-1|CAE46049.1|  321|Homo sapiens hypothetical protein
           protein.
          Length = 321

 Score =  135 bits (326), Expect = 4e-31
 Identities = 74/208 (35%), Positives = 104/208 (50%), Gaps = 8/208 (3%)

Query: 83  ECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQCSRHN 142
           E S   G G    ++  + P   +    CIG   +YK+CNT+ CP +  S REVQC+ +N
Sbjct: 62  ETSNNHGVGTHGATQSFSQPAR-STAISCIGAYRQYKLCNTNVCPESSRSIREVQCASYN 120

Query: 143 NMPYKNETIDEWVPYFDQ--DKPCELQCVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCI 200
           N P+      EW P+ +   ++ CEL C              V DGTPC Q      +C+
Sbjct: 121 NKPFMGRFY-EWEPFAEVKGNRKCELNCQAMGYRFYVRQAEKVIDGTPCDQ--NGTAICV 177

Query: 201 SGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSR 260
           SG C  +GCD  + SD   D CGVCGGD T C+ V G++    T   G+  V  IP G+ 
Sbjct: 178 SGQCKSIGCDDYLGSDKVVDKCGVCGGDNTGCQVVSGVFKHALT-SLGYHRVVEIPEGAT 236

Query: 261 NVKIQEKVSPGNYISIGSTKSRRMFLNG 288
            + I E     NY+++ S +S R  +NG
Sbjct: 237 KINITEMYKSNNYLALRS-RSGRSIING 263


>AK131414-1|BAD18561.1|  493|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16524 fis, clone OCBBF2003327, moderately
           similar to ADAM-TS 6 precursor (EC 3.4.24.-). ).
          Length = 493

 Score =  128 bits (308), Expect = 6e-29
 Identities = 93/322 (28%), Positives = 146/322 (45%), Gaps = 25/322 (7%)

Query: 164 CELQCVPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACG 223
           C L C+             V DGTPCR    + D+C+SG C  VGCD ++ SD+ ED C 
Sbjct: 126 CSLTCLAEGFNFYTERAAAVVDGTPCRP--DTVDICVSGECKHVGCDRVLGSDLREDKCR 183

Query: 224 VCGGDGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRR 283
           VCGGDG+AC+T++G+++  +   +G+ +V  IP GS ++ IQ+     N++++   +   
Sbjct: 184 VCGGDGSACETIEGVFSPASP-GAGYEDVVWIPKGSVHIFIQDLNLSLNHLALKGDQ-ES 241

Query: 284 MFLNGARNATLTEYF-VAGAQAIYERDRDW-EKVRISGPLAEDIKVYQRIFRGRHRNPGV 341
           + L G           +AG      +  D  + +   GP+   + V   +   R   P +
Sbjct: 242 LLLEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIV---MVLARTELPAL 298

Query: 342 TYQYTVDKQR-LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQRVVEQSQC-YHIE 398
            Y++     R     +S+  + WT CS  C  G   +  EC +Q     V    C  H +
Sbjct: 299 RYRFNAPIARDSLPPYSWHYAPWTRCSAQCAGGSQVQAVECRNQLDGSAVAPHYCSAHSK 358

Query: 399 PPRHQALMKQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYC---VDKVMNKVVD 454
            P+ Q   + C    C   W VG W+ CS+ C    +   + RSV C   V     K +D
Sbjct: 359 LPKRQ---RACNTEPCPPDWVVGNWSLCSRSC----DAGVRSRSVVCQRRVSAAEEKALD 411

Query: 455 DSECGQVIKPITTIKCADVPAC 476
           DS C Q   P+  ++    P C
Sbjct: 412 DSACPQPRPPV--LEACHGPTC 431



 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 13/116 (11%)

Query: 360 LSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
           +  W+ CS +C  G   R   C  +     ++ ++ S C    PP    +++ C  P C 
Sbjct: 377 VGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPP----VLEACHGPTCP 432

Query: 416 HWWVGA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
             W    W+ C+  C  PG    + R V C        +  + C    KP  T++C
Sbjct: 433 PEWAALDWSECTPSCG-PG---LRHRVVLCKSADHRATLPPAHCSPAAKPPATMRC 484



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 5/55 (9%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNN--PEPVNNGNYCIGDR---SRYKVCNTDPCP 127
           ++ W+ CS  C  G   Q+ EC N         +YC        R + CNT+PCP
Sbjct: 318 YAPWTRCSAQCAGGSQVQAVECRNQLDGSAVAPHYCSAHSKLPKRQRACNTEPCP 372


>AK131403-1|BAD18550.1|  415|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16501 fis, clone FEBRA2006519, weakly  similar
           to Mus musculus papilin mRNA. ).
          Length = 415

 Score =  121 bits (292), Expect = 5e-27
 Identities = 89/285 (31%), Positives = 135/285 (47%), Gaps = 28/285 (9%)

Query: 179 LGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGI 238
           + G V DGTPC       D+CI GVC  VGCD  + S    DACGVC GD + CK  +G+
Sbjct: 75  MSGKVKDGTPCSP--NKNDVCIDGVCELVGCDHELGSKAVSDACGVCKGDNSTCKFYKGL 132

Query: 239 YTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNGARNATLTEYF 298
           Y     + + +  V +IPAG+R+++IQE     +Y+++ S   +     G       E+ 
Sbjct: 133 YL-NQHKANEYYPVVLIPAGARSIEIQELQVSSSYLAVRSLSQKHYLTGGWSIDWPGEFP 191

Query: 299 VAGAQAIYERDRDW-EKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDK-----QRL 352
            AG    Y+R  +  E++   GP  E + V++ + +G  +NPG+ ++Y + K        
Sbjct: 192 FAGTTFEYQRSFNRPERLYAPGPTNETL-VFEILMQG--KNPGIAWKYALPKVMNGTPPA 248

Query: 353 HKKHSYRLS-EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRK 411
            K+ +Y  S   + CSV+CG GY      C+      V  S C     P  +   K C +
Sbjct: 249 TKRPAYTWSIVQSECSVSCGGGYINVKAICLRDQNTQVNSSFCSAKTKPVTEP--KICNR 306

Query: 412 PAC-VH--------WWVGAWNPCSKLCHMPGEEVTKERSVYCVDK 447
            AC  H        W+   W  C+  C   G  V + RSV+CV +
Sbjct: 307 RACPAHPVYNMVAGWYSLPWQQCTVTC---GGGV-QTRSVHCVQQ 347



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 16/50 (32%), Positives = 23/50 (46%)

Query: 81  WSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           W +C+ TCG GV T+S  C      ++           + CNT+ CP  E
Sbjct: 326 WQQCTVTCGGGVQTRSVHCVQQGRPSSSCLLHQKPPVLRACNTNFCPAPE 375


>AY358122-1|AAQ88489.1|  877|Homo sapiens ENWT2803 protein.
          Length = 877

 Score =  120 bits (289), Expect = 1e-26
 Identities = 73/243 (30%), Positives = 113/243 (46%), Gaps = 13/243 (5%)

Query: 111 CIGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQC 168
           C G+  + + C+  PCP  +P  R +QC+  N+  +  + + +W P+ +    + CEL C
Sbjct: 364 CSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQ-LYQWEPFTEVQGSQRCELNC 422

Query: 169 VPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGD 228
            PR           V DGT C+   G+ D+C++G C   GCD I+ S    D CGVCGGD
Sbjct: 423 RPRGFRFYVRHTEKVQDGTLCQP--GAPDICVAGRCLSPGCDGILGSGRRPDGCGVCGGD 480

Query: 229 GTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNG 288
            + C+ V G  T       G+ ++  IPAG+  ++I +     NY+++     R +    
Sbjct: 481 DSTCRLVSGNLT-DRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGN 539

Query: 289 ARNATLTEYFVAGAQAIYER----DRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQ 344
                   Y   G    Y R    +   E +   GP  + + VY  IF  +  NPGV YQ
Sbjct: 540 WAVDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYM-IF--QEENPGVFYQ 596

Query: 345 YTV 347
           Y +
Sbjct: 597 YVI 599



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 16/31 (51%), Positives = 21/31 (67%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
           +G WGPW +W+ CS+ CG GV  +SR C  P
Sbjct: 44  EGVWGPWVQWASCSQPCGVGVQRRSRTCQLP 74



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQH---QRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           +   EWT CS +CG G   R  +C  +       V   +C H+  P    + + C+   C
Sbjct: 727 WEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLPRPN---ITQSCQLRLC 783

Query: 415 VHWWVGA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            HW VG+ W+ CS  C   G+   + R V CV    ++ V + EC
Sbjct: 784 GHWEVGSPWSQCSVRCGR-GQ---RSRQVRCVGNNGDE-VSEQEC 823



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 12/110 (10%)

Query: 366 CSVTCGVGYTRRYYECIDQH--QRVVEQSQCYHIEPPRHQALMKQCRKPACVHWW-VGAW 422
           CS +CG G  R  + CI +   + + E+S      PP   A  + C    C  +W  G W
Sbjct: 676 CSASCGKGVWRPIFLCISRESGEELDERSCAAGARPP---ASPEPCHGTPCPPYWEAGEW 732

Query: 423 NPCSKLCHMPGEEVTKERSVYCVDKV--MNKVVDDSECGQVIKPITTIKC 470
             CS+ C  PG   T+ R + C  +       V    CG + +P  T  C
Sbjct: 733 TSCSRSCG-PG---TQHRQLQCRQEFGGGGSSVPPERCGHLPRPNITQSC 778



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 17/63 (26%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSV CG G   R   C+  +   V + +C    PP+  +       P    W+  
Sbjct: 790 SPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECAS-GPPQPPSREACDMGPCTTAWFHS 848

Query: 421 AWN 423
            W+
Sbjct: 849 DWS 851



 Score = 33.1 bits (72), Expect = 2.2
 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSREC--NNPEPVNNGNYCIG--DRSRYKVCNTDPC 126
           G W   S WS+CS  CG G  ++   C  NN + V+      G       + C+  PC
Sbjct: 784 GHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREACDMGPC 841



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 63  ARTP-SPAPRDGGWGP--WS--EWSECSRTCGAGVSTQSREC 99
           AR P SP P  G   P  W   EW+ CSR+CG G   +  +C
Sbjct: 709 ARPPASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQC 750


>AL356356-13|CAI15500.2| 1074|Homo sapiens ADAMTS-like 4 protein.
          Length = 1074

 Score =  120 bits (289), Expect = 1e-26
 Identities = 73/243 (30%), Positives = 113/243 (46%), Gaps = 13/243 (5%)

Query: 111 CIGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQC 168
           C G+  + + C+  PCP  +P  R +QC+  N+  +  + + +W P+ +    + CEL C
Sbjct: 364 CSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQ-LYQWEPFTEVQGSQRCELNC 422

Query: 169 VPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGD 228
            PR           V DGT C+   G+ D+C++G C   GCD I+ S    D CGVCGGD
Sbjct: 423 RPRGFRFYVRHTEKVQDGTLCQP--GAPDICVAGRCLSPGCDGILGSGRRPDGCGVCGGD 480

Query: 229 GTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNG 288
            + C+ V G  T       G+ ++  IPAG+  ++I +     NY+++     R +    
Sbjct: 481 DSTCRLVSGNLT-DRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGN 539

Query: 289 ARNATLTEYFVAGAQAIYER----DRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQ 344
                   Y   G    Y R    +   E +   GP  + + VY  IF  +  NPGV YQ
Sbjct: 540 WAVDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYM-IF--QEENPGVFYQ 596

Query: 345 YTV 347
           Y +
Sbjct: 597 YVI 599



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 16/31 (51%), Positives = 21/31 (67%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
           +G WGPW +W+ CS+ CG GV  +SR C  P
Sbjct: 44  EGVWGPWVQWASCSQPCGVGVQRRSRTCQLP 74



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQH---QRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           +   EWT CS +CG G   R  +C  +       V   +C H+  P    + + C+   C
Sbjct: 727 WEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLPRPN---ITQSCQLRLC 783

Query: 415 VHWWVGA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            HW VG+ W+ CS  C   G+   + R V CV    ++ V + EC
Sbjct: 784 GHWEVGSPWSQCSVRCGR-GQ---RSRQVRCVGNNGDE-VSEQEC 823



 Score = 48.4 bits (110), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 14/116 (12%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQ---HQRVVEQSQCYHIEPPRHQALMKQCRKPACV-HWW 418
            W  CS  CG G  RR   C+ +      V   S C H+  PR  AL + C+  AC   W+
Sbjct: 919  WGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHL--PRPPAL-QPCQGQACQDRWF 975

Query: 419  VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
               W+PCS+ C    +  T+ R V C+    N+ +  + C   ++P     C   P
Sbjct: 976  STPWSPCSRSC----QGGTQTREVQCLS--TNQTL-STRCPPQLRPSRKRPCNSQP 1024



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 12/110 (10%)

Query: 366 CSVTCGVGYTRRYYECIDQH--QRVVEQSQCYHIEPPRHQALMKQCRKPACVHWW-VGAW 422
           CS +CG G  R  + CI +   + + E+S      PP   A  + C    C  +W  G W
Sbjct: 676 CSASCGKGVWRPIFLCISRESGEELDERSCAAGARPP---ASPEPCHGTPCPPYWEAGEW 732

Query: 423 NPCSKLCHMPGEEVTKERSVYCVDKV--MNKVVDDSECGQVIKPITTIKC 470
             CS+ C  PG   T+ R + C  +       V    CG + +P  T  C
Sbjct: 733 TSCSRSCG-PG---TQHRQLQCRQEFGGGGSSVPPERCGHLPRPNITQSC 778



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSV CG G   R   C+  +   V + +C    PP+  +       P    W+  
Sbjct: 790 SPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECAS-GPPQPPSREACDMGPCTTAWFHS 848

Query: 421 AW-NPCSKLCHMPGEEVTKERSVYCV 445
            W + CS  C   G  + + RSV C+
Sbjct: 849 DWSSKCSAEC---GTGI-QRRSVVCL 870



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 20/124 (16%)

Query: 361 SEWTP-CSVTCGVGYTRRYYECIDQHQRV----------VEQSQCYHIEPPRHQAL-MKQ 408
           S+W+  CS  CG G  RR   C+     +            QS      PP  +A  +  
Sbjct: 848 SDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDMRACSLGP 907

Query: 409 CRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNK--VVDDSECGQVIKPIT 466
           C +     W+ G W  CS  C       T+ R + CV K+  +  V   S C  + +P  
Sbjct: 908 CERTW--RWYTGPWGECSSEC----GSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPPA 961

Query: 467 TIKC 470
              C
Sbjct: 962 LQPC 965



 Score = 33.1 bits (72), Expect = 2.2
 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSREC--NNPEPVNNGNYCIG--DRSRYKVCNTDPC 126
           G W   S WS+CS  CG G  ++   C  NN + V+      G       + C+  PC
Sbjct: 784 GHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREACDMGPC 841



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 81   WSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
            WS CSR+C  G  T+  +C +     +       R SR + CN+ PC
Sbjct: 979  WSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRKRPCNSQPC 1025



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 63  ARTP-SPAPRDGGWGP--WS--EWSECSRTCGAGVSTQSREC 99
           AR P SP P  G   P  W   EW+ CSR+CG G   +  +C
Sbjct: 709 ARPPASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQC 750


>AL356356-12|CAI15499.1|  877|Homo sapiens ADAMTS-like 4 protein.
          Length = 877

 Score =  120 bits (289), Expect = 1e-26
 Identities = 73/243 (30%), Positives = 113/243 (46%), Gaps = 13/243 (5%)

Query: 111 CIGDRSRYKVCNTDPCPINEPSFREVQCSRHNNMPYKNETIDEWVPYFDQD--KPCELQC 168
           C G+  + + C+  PCP  +P  R +QC+  N+  +  + + +W P+ +    + CEL C
Sbjct: 364 CSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQ-LYQWEPFTEVQGSQRCELNC 422

Query: 169 VPRDGTDVEMLGGFVADGTPCRQAIGSRDMCISGVCYKVGCDWIVDSDVEEDACGVCGGD 228
            PR           V DGT C+   G+ D+C++G C   GCD I+ S    D CGVCGGD
Sbjct: 423 RPRGFRFYVRHTEKVQDGTLCQP--GAPDICVAGRCLSPGCDGILGSGRRPDGCGVCGGD 480

Query: 229 GTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKSRRMFLNG 288
            + C+ V G  T       G+ ++  IPAG+  ++I +     NY+++     R +    
Sbjct: 481 DSTCRLVSGNLT-DRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGN 539

Query: 289 ARNATLTEYFVAGAQAIYER----DRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQ 344
                   Y   G    Y R    +   E +   GP  + + VY  IF  +  NPGV YQ
Sbjct: 540 WAVDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYM-IF--QEENPGVFYQ 596

Query: 345 YTV 347
           Y +
Sbjct: 597 YVI 599



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 16/31 (51%), Positives = 21/31 (67%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
           +G WGPW +W+ CS+ CG GV  +SR C  P
Sbjct: 44  EGVWGPWVQWASCSQPCGVGVQRRSRTCQLP 74



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQH---QRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           +   EWT CS +CG G   R  +C  +       V   +C H+  P    + + C+   C
Sbjct: 727 WEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLPRPN---ITQSCQLRLC 783

Query: 415 VHWWVGA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            HW VG+ W+ CS  C   G+   + R V CV    ++ V + EC
Sbjct: 784 GHWEVGSPWSQCSVRCGR-GQ---RSRQVRCVGNNGDE-VSEQEC 823



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 12/110 (10%)

Query: 366 CSVTCGVGYTRRYYECIDQH--QRVVEQSQCYHIEPPRHQALMKQCRKPACVHWW-VGAW 422
           CS +CG G  R  + CI +   + + E+S      PP   A  + C    C  +W  G W
Sbjct: 676 CSASCGKGVWRPIFLCISRESGEELDERSCAAGARPP---ASPEPCHGTPCPPYWEAGEW 732

Query: 423 NPCSKLCHMPGEEVTKERSVYCVDKV--MNKVVDDSECGQVIKPITTIKC 470
             CS+ C  PG   T+ R + C  +       V    CG + +P  T  C
Sbjct: 733 TSCSRSCG-PG---TQHRQLQCRQEFGGGGSSVPPERCGHLPRPNITQSC 778



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 17/63 (26%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSV CG G   R   C+  +   V + +C    PP+  +       P    W+  
Sbjct: 790 SPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECAS-GPPQPPSREACDMGPCTTAWFHS 848

Query: 421 AWN 423
            W+
Sbjct: 849 DWS 851



 Score = 33.1 bits (72), Expect = 2.2
 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSREC--NNPEPVNNGNYCIG--DRSRYKVCNTDPC 126
           G W   S WS+CS  CG G  ++   C  NN + V+      G       + C+  PC
Sbjct: 784 GHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREACDMGPC 841



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 63  ARTP-SPAPRDGGWGP--WS--EWSECSRTCGAGVSTQSREC 99
           AR P SP P  G   P  W   EW+ CSR+CG G   +  +C
Sbjct: 709 ARPPASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQC 750


>BC042057-1|AAH42057.1|  129|Homo sapiens PAPLN protein protein.
          Length = 129

 Score = 95.9 bits (228), Expect = 3e-19
 Identities = 37/97 (38%), Positives = 55/97 (56%), Gaps = 2/97 (2%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFR 134
           WGPWS+WS CSRTCG GVS + R C + +  + G+ C+G    ++ C T+ CP     FR
Sbjct: 29  WGPWSQWSPCSRTCGGGVSFRERPCYS-QRRDGGSSCVGPARSHRSCRTESCPDGARDFR 87

Query: 135 EVQCSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPR 171
             QC+  +   ++      W+PY+     CEL C+P+
Sbjct: 88  AEQCAEFDGAEFQGRRY-RWLPYYSAPNKCELNCIPK 123



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 7/54 (12%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           S+W+PCS TCG G + R   C    QR    S C  + P R     + CR  +C
Sbjct: 33  SQWSPCSRTCGGGVSFRERPCYS--QRRDGGSSC--VGPARSH---RSCRTESC 79


>X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA
           -31 to 1139) protein.
          Length = 1170

 Score = 88.2 bits (209), Expect = 6e-17
 Identities = 37/82 (45%), Positives = 49/82 (59%), Gaps = 4/82 (4%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPI- 128
           P +GGWGPWS W  CS TCG GV  +SR CNNP P   G  C+GD +  ++CN   CPI 
Sbjct: 490 PINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPAPQFGGKDCVGDVTENQICNKQDCPID 549

Query: 129 ---NEPSFREVQCSRHNNMPYK 147
              + P F  V+C+ + +  +K
Sbjct: 550 GCLSNPCFAGVKCTSYPDGSWK 571



 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/74 (47%), Positives = 41/74 (55%), Gaps = 1/74 (1%)

Query: 57  QNQTC-VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR 115
           Q +TC +        +DGGW  WS WS CS TCG GV T+ R CN+P P  NG  C G+ 
Sbjct: 419 QTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEA 478

Query: 116 SRYKVCNTDPCPIN 129
              K C  D CPIN
Sbjct: 479 RETKACKKDACPIN 492



 Score = 57.6 bits (133), Expect = 9e-08
 Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 6/96 (6%)

Query: 31  CLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGA 90
           C   N  T   + + P   C        + C    PS +  D GW PWSEW+ CS +CG 
Sbjct: 339 CHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSA-DDGWSPWSEWTSCSTSCGN 397

Query: 91  GVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           G+  + R C++   +N  N C G   + + C+   C
Sbjct: 398 GIQQRGRSCDS---LN--NRCEGSSVQTRTCHIQEC 428



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 10/73 (13%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWV 419
           S W+ CSVTCG G   R   C +     +    C   E    +   K C+K AC ++   
Sbjct: 442 SPWSSCSVTCGDGVITRIRLC-NSPSPQMNGKPC---EGEARET--KACKKDACPINGGW 495

Query: 420 GAWNP---CSKLC 429
           G W+P   CS  C
Sbjct: 496 GPWSPWDICSVTC 508



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 9/72 (12%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRV---VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
           SEWT CS +CG G  +R   C   + R      Q++  HI+        KQ       HW
Sbjct: 386 SEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQ--ECDKRFKQ--DGGWSHW 441

Query: 418 WVGAWNPCSKLC 429
               W+ CS  C
Sbjct: 442 --SPWSSCSVTC 451


>X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for
           thrombospondin. ).
          Length = 1170

 Score = 88.2 bits (209), Expect = 6e-17
 Identities = 37/82 (45%), Positives = 49/82 (59%), Gaps = 4/82 (4%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPI- 128
           P +GGWGPWS W  CS TCG GV  +SR CNNP P   G  C+GD +  ++CN   CPI 
Sbjct: 490 PINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPID 549

Query: 129 ---NEPSFREVQCSRHNNMPYK 147
              + P F  V+C+ + +  +K
Sbjct: 550 GCLSNPCFAGVKCTSYPDGSWK 571



 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/74 (47%), Positives = 41/74 (55%), Gaps = 1/74 (1%)

Query: 57  QNQTC-VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR 115
           Q +TC +        +DGGW  WS WS CS TCG GV T+ R CN+P P  NG  C G+ 
Sbjct: 419 QTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEA 478

Query: 116 SRYKVCNTDPCPIN 129
              K C  D CPIN
Sbjct: 479 RETKACKKDACPIN 492



 Score = 57.6 bits (133), Expect = 9e-08
 Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 6/96 (6%)

Query: 31  CLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGA 90
           C   N  T   + + P   C        + C    PS +  D GW PWSEW+ CS +CG 
Sbjct: 339 CHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSA-DDGWSPWSEWTSCSTSCGN 397

Query: 91  GVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           G+  + R C++   +N  N C G   + + C+   C
Sbjct: 398 GIQQRGRSCDS---LN--NRCEGSSVQTRTCHIQEC 428



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 10/73 (13%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWV 419
           S W+ CSVTCG G   R   C +     +    C   E    +   K C+K AC ++   
Sbjct: 442 SPWSSCSVTCGDGVITRIRLC-NSPSPQMNGKPC---EGEARET--KACKKDACPINGGW 495

Query: 420 GAWNP---CSKLC 429
           G W+P   CS  C
Sbjct: 496 GPWSPWDICSVTC 508



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 9/72 (12%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRV---VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
           SEWT CS +CG G  +R   C   + R      Q++  HI+        KQ       HW
Sbjct: 386 SEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQ--ECDKRFKQ--DGGWSHW 441

Query: 418 WVGAWNPCSKLC 429
               W+ CS  C
Sbjct: 442 --SPWSSCSVTC 451


>AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precursor
           variant protein.
          Length = 1225

 Score = 88.2 bits (209), Expect = 6e-17
 Identities = 37/82 (45%), Positives = 49/82 (59%), Gaps = 4/82 (4%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPI- 128
           P +GGWGPWS W  CS TCG GV  +SR CNNP P   G  C+GD +  ++CN   CPI 
Sbjct: 545 PINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPID 604

Query: 129 ---NEPSFREVQCSRHNNMPYK 147
              + P F  V+C+ + +  +K
Sbjct: 605 GCLSNPCFAGVKCTSYPDGSWK 626



 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/74 (47%), Positives = 41/74 (55%), Gaps = 1/74 (1%)

Query: 57  QNQTC-VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR 115
           Q +TC +        +DGGW  WS WS CS TCG GV T+ R CN+P P  NG  C G+ 
Sbjct: 474 QTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEA 533

Query: 116 SRYKVCNTDPCPIN 129
              K C  D CPIN
Sbjct: 534 RETKACKKDACPIN 547



 Score = 57.6 bits (133), Expect = 9e-08
 Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 6/96 (6%)

Query: 31  CLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGA 90
           C   N  T   + + P   C        + C    PS +  D GW PWSEW+ CS +CG 
Sbjct: 394 CHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSA-DDGWSPWSEWTSCSTSCGN 452

Query: 91  GVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           G+  + R C++   +N  N C G   + + C+   C
Sbjct: 453 GIQQRGRSCDS---LN--NRCEGSSVQTRTCHIQEC 483



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 10/73 (13%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWV 419
           S W+ CSVTCG G   R   C +     +    C   E    +   K C+K AC ++   
Sbjct: 497 SPWSSCSVTCGDGVITRIRLC-NSPSPQMNGKPC---EGEARET--KACKKDACPINGGW 550

Query: 420 GAWNP---CSKLC 429
           G W+P   CS  C
Sbjct: 551 GPWSPWDICSVTC 563



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 9/72 (12%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRV---VEQSQCYHIEPPRHQALMKQCRKPACVHW 417
           SEWT CS +CG G  +R   C   + R      Q++  HI+        KQ       HW
Sbjct: 441 SEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQ--ECDKRFKQ--DGGWSHW 496

Query: 418 WVGAWNPCSKLC 429
               W+ CS  C
Sbjct: 497 --SPWSSCSVTC 506


>L12350-1|AAA03703.1| 1172|Homo sapiens thrombospondin 2 protein.
          Length = 1172

 Score = 83.4 bits (197), Expect = 2e-15
 Identities = 33/77 (42%), Positives = 44/77 (57%), Gaps = 4/77 (5%)

Query: 67  SPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           +P P DG W PWS WS C+ TC  G+  ++R CN+PEP   G  C+GD    ++CN   C
Sbjct: 489 APCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSC 548

Query: 127 PI----NEPSFREVQCS 139
           P+    + P F   QCS
Sbjct: 549 PVDGCLSNPCFPGAQCS 565



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 35/83 (42%), Positives = 45/83 (54%), Gaps = 4/83 (4%)

Query: 49  TC-GPDMWCQNQTC-VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           TC GP +  Q + C +++  +   +DGGW  WS WS CS TCG G  T+ R CN+P P  
Sbjct: 414 TCLGPSI--QTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQM 471

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G     K C   PCPI+
Sbjct: 472 GGKNCKGSGRETKACQGAPCPID 494



 Score = 57.2 bits (132), Expect = 1e-07
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 6/96 (6%)

Query: 31  CLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGA 90
           C      T   +   P  TC    + + + C +   S    + GW PW+EW++CS TCG+
Sbjct: 341 CTCKKFKTICHQITCPPATCASPSFVEGECCPSCLHS-VDGEEGWSPWAEWTQCSVTCGS 399

Query: 91  GVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           G   + R C+        N C+G   + + C+   C
Sbjct: 400 GTQQRGRSCD-----VTSNTCLGPSIQTRACSLSKC 430



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 12/21 (57%), Positives = 14/21 (66%)

Query: 361 SEWTPCSVTCGVGYTRRYYEC 381
           +EWT CSVTCG G  +R   C
Sbjct: 388 AEWTQCSVTCGSGTQQRGRSC 408


>BX322234-1|CAI23645.1| 1172|Homo sapiens thrombospondin 2 protein.
          Length = 1172

 Score = 83.4 bits (197), Expect = 2e-15
 Identities = 33/77 (42%), Positives = 44/77 (57%), Gaps = 4/77 (5%)

Query: 67  SPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           +P P DG W PWS WS C+ TC  G+  ++R CN+PEP   G  C+GD    ++CN   C
Sbjct: 489 APCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSC 548

Query: 127 PI----NEPSFREVQCS 139
           P+    + P F   QCS
Sbjct: 549 PVDGCLSNPCFPGAQCS 565



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 35/83 (42%), Positives = 45/83 (54%), Gaps = 4/83 (4%)

Query: 49  TC-GPDMWCQNQTC-VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           TC GP +  Q + C +++  +   +DGGW  WS WS CS TCG G  T+ R CN+P P  
Sbjct: 414 TCLGPSI--QTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQM 471

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G     K C   PCPI+
Sbjct: 472 GGKNCKGSGRETKACQGAPCPID 494



 Score = 57.2 bits (132), Expect = 1e-07
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 6/96 (6%)

Query: 31  CLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGA 90
           C      T   +   P  TC    + + + C +   S    + GW PW+EW++CS TCG+
Sbjct: 341 CTCKKFKTICHQITCPPATCASPSFVEGECCPSCLHS-VDGEEGWSPWAEWTQCSVTCGS 399

Query: 91  GVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           G   + R C+        N C+G   + + C+   C
Sbjct: 400 GTQQRGRSCD-----VTSNTCLGPSIQTRACSLSKC 430



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 12/21 (57%), Positives = 14/21 (66%)

Query: 361 SEWTPCSVTCGVGYTRRYYEC 381
           +EWT CSVTCG G  +R   C
Sbjct: 388 AEWTQCSVTCGSGTQQRGRSC 408


>X70872-1|CAA50220.1|  469|Homo sapiens properdin protein.
          Length = 469

 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 46  PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           PG  C P +  + + C    P P    GGWGPW   S C  TCG G + + R CN+P P 
Sbjct: 234 PGKPC-PGLAYEQRRCTGLPPCPVA--GGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQ 290

Query: 106 NNGNYCIGDRSRYKVCNTD-PCPIN 129
           + G +C GD +R  +CNT  PCP++
Sbjct: 291 HGGPFCAGDATRTHICNTAVPCPVD 315



 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 45  APGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           APGT       C++Q C        P  GGW  W  W  CS TC  G  T+ R CN+P P
Sbjct: 116 APGTLEWQLQACEDQQC-------CPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAP 168

Query: 105 VNNGNYCIGDRSRYKVCNTDP-CP 127
              G +C G     + C+T   CP
Sbjct: 169 -KCGGHCPGQAQESEACDTQQVCP 191



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 8/91 (8%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAG----VSTQSRECN 100
           P   CG     Q Q   A  T    P  G W  W  W+ CS +C  G      T+SR+C+
Sbjct: 166 PAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS 225

Query: 101 NPEPVNN--GNYCIGDRSRYKVC-NTDPCPI 128
            PEP     G  C G     + C    PCP+
Sbjct: 226 APEPSQKPPGKPCPGLAYEQRRCTGLPPCPV 256



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W PCSVTC  G   RY  C+  + +   +     +E        +QC  P    W  W
Sbjct: 84  STWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC-CPEMGGWSGW 142

Query: 419 VGAWNPCSKLC 429
            G W PCS  C
Sbjct: 143 -GPWEPCSVTC 152



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSR------TCG--AGVST 94
           P   G  C  D     +T +  T  P P DG W  W EWS C R      +C    G  +
Sbjct: 289 PQHGGPFCAGDA---TRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQS 345

Query: 95  QSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPI 128
           + R C   +   +G+ C G +   + C +   CP+
Sbjct: 346 RGRTCRGRK--FDGHRCAGQQQDIRHCYSIQHCPL 378



 Score = 37.9 bits (84), Expect = 0.077
 Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 6/84 (7%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--WVG 420
           W PCSVTC  G   R   C   H        C   +    +A   Q   P    W  W G
Sbjct: 145 WEPCSVTCSKGTRTRRRAC--NHPAPKCGGHCPG-QAQESEACDTQQVCPTHGAWATW-G 200

Query: 421 AWNPCSKLCHMPGEEVTKERSVYC 444
            W PCS  CH    E  + RS  C
Sbjct: 201 PWTPCSASCHGGPHEPKETRSRKC 224



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 3/34 (8%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           P  +PR   W  WS W+ CS TC  G   + R C
Sbjct: 74  PCRSPR---WSLWSTWAPCSVTCSEGSQLRYRRC 104


>X57748-1|CAA40914.1|  469|Homo sapiens properdin protein.
          Length = 469

 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 46  PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           PG  C P +  + + C    P P    GGWGPW   S C  TCG G + + R CN+P P 
Sbjct: 234 PGKPC-PGLAYEQRRCTGLPPCPVA--GGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQ 290

Query: 106 NNGNYCIGDRSRYKVCNTD-PCPIN 129
           + G +C GD +R  +CNT  PCP++
Sbjct: 291 HGGPFCAGDATRTHICNTAVPCPVD 315



 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 45  APGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           APGT       C++Q C        P  GGW  W  W  CS TC  G  T+ R CN+P P
Sbjct: 116 APGTLEWQLQACEDQQC-------CPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAP 168

Query: 105 VNNGNYCIGDRSRYKVCNTDP-CP 127
              G +C G     + C+T   CP
Sbjct: 169 -KCGGHCPGQAQESEACDTQQVCP 191



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 8/91 (8%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAG----VSTQSRECN 100
           P   CG     Q Q   A  T    P  G W  W  W+ CS +C  G      T+SR+C+
Sbjct: 166 PAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS 225

Query: 101 NPEPVNN--GNYCIGDRSRYKVC-NTDPCPI 128
            PEP     G  C G     + C    PCP+
Sbjct: 226 APEPSQKPPGKPCPGLAYEQRRCTGLPPCPV 256



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W PCSVTC  G   RY  C+  + +   +     +E        +QC  P    W  W
Sbjct: 84  STWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC-CPEMGGWSGW 142

Query: 419 VGAWNPCSKLC 429
            G W PCS  C
Sbjct: 143 -GPWEPCSVTC 152



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSR------TCG--AGVST 94
           P   G  C  D     +T +  T  P P DG W  W EWS C R      +C    G  +
Sbjct: 289 PQHGGPFCAGDA---TRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQS 345

Query: 95  QSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPI 128
           + R C   +   +G+ C G +   + C +   CP+
Sbjct: 346 RGRTCRGRK--FDGHRCAGQQQDIRHCYSIQHCPL 378



 Score = 37.9 bits (84), Expect = 0.077
 Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 6/84 (7%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--WVG 420
           W PCSVTC  G   R   C   H        C   +    +A   Q   P    W  W G
Sbjct: 145 WEPCSVTCSKGTRTRRRAC--NHPAPKCGGHCPG-QAQESEACDTQQVCPTHGAWATW-G 200

Query: 421 AWNPCSKLCHMPGEEVTKERSVYC 444
            W PCS  CH    E  + RS  C
Sbjct: 201 PWTPCSASCHGGPHEPKETRSRKC 224



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 3/34 (8%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           P  +PR   W  WS W+ CS TC  G   + R C
Sbjct: 74  PCRSPR---WSLWSTWAPCSVTCSEGSQLRYRRC 104


>M83652-1|AAA36489.1|  469|Homo sapiens complement omponent
           properdin protein.
          Length = 469

 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 46  PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           PG  C P +  + + C    P P    GGWGPW   S C  TCG G + + R CN+P P 
Sbjct: 234 PGKPC-PGLAYEQRRCTGLPPCPVA--GGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQ 290

Query: 106 NNGNYCIGDRSRYKVCNTD-PCPIN 129
           + G +C GD +R  +CNT  PCP++
Sbjct: 291 HGGPFCAGDATRTHICNTAVPCPVD 315



 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 45  APGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           APGT       C++Q C        P  GGW  W  W  CS TC  G  T+ R CN+P P
Sbjct: 116 APGTLEWQLQACEDQQC-------CPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAP 168

Query: 105 VNNGNYCIGDRSRYKVCNTDP-CP 127
              G +C G     + C+T   CP
Sbjct: 169 -KCGGHCPGQAQESEACDTQQVCP 191



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 8/91 (8%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAG----VSTQSRECN 100
           P   CG     Q Q   A  T    P  G W  W  W+ CS +C  G      T+SR+C+
Sbjct: 166 PAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS 225

Query: 101 NPEPVNN--GNYCIGDRSRYKVC-NTDPCPI 128
            PEP     G  C G     + C    PCP+
Sbjct: 226 APEPSQKPPGKPCPGLAYEQRRCTGLPPCPV 256



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W PCSVTC  G   RY  C+  + +   +     +E        +QC  P    W  W
Sbjct: 84  STWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC-CPEMGGWSGW 142

Query: 419 VGAWNPCSKLC 429
            G W PCS  C
Sbjct: 143 -GPWEPCSVTC 152



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSR------TCG--AGVST 94
           P   G  C  D     +T +  T  P P DG W  W EWS C R      +C    G  +
Sbjct: 289 PQHGGPFCAGDA---TRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQS 345

Query: 95  QSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPI 128
           + R C   +   +G+ C G +   + C +   CP+
Sbjct: 346 RGRTCRGRK--FDGHRCAGQQQDIRHCYSIQHCPL 378



 Score = 37.9 bits (84), Expect = 0.077
 Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 6/84 (7%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--WVG 420
           W PCSVTC  G   R   C   H        C   +    +A   Q   P    W  W G
Sbjct: 145 WEPCSVTCSKGTRTRRRAC--NHPAPKCGGHCPG-QAQESEACDTQQVCPTHGAWATW-G 200

Query: 421 AWNPCSKLCHMPGEEVTKERSVYC 444
            W PCS  CH    E  + RS  C
Sbjct: 201 PWTPCSASCHGGPHEPKETRSRKC 224



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 3/34 (8%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           P  +PR   W  WS W+ CS TC  G   + R C
Sbjct: 74  PCRSPR---WSLWSTWAPCSVTCSEGSQLRYRRC 104


>BC015756-1|AAH15756.1|  469|Homo sapiens complement factor
           properdin protein.
          Length = 469

 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 46  PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           PG  C P +  + + C    P P    GGWGPW   S C  TCG G + + R CN+P P 
Sbjct: 234 PGKPC-PGLAYEQRRCTGLPPCPVA--GGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQ 290

Query: 106 NNGNYCIGDRSRYKVCNTD-PCPIN 129
           + G +C GD +R  +CNT  PCP++
Sbjct: 291 HGGPFCAGDATRTHICNTAVPCPVD 315



 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 45  APGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           APGT       C++Q C        P  GGW  W  W  CS TC  G  T+ R CN+P P
Sbjct: 116 APGTLEWQLQACEDQQC-------CPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAP 168

Query: 105 VNNGNYCIGDRSRYKVCNTDP-CP 127
              G +C G     + C+T   CP
Sbjct: 169 -KCGGHCPGQAQESEACDTQQVCP 191



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 8/91 (8%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAG----VSTQSRECN 100
           P   CG     Q Q   A  T    P  G W  W  W+ CS +C  G      T+SR+C+
Sbjct: 166 PAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS 225

Query: 101 NPEPVNN--GNYCIGDRSRYKVC-NTDPCPI 128
            PEP     G  C G     + C    PCP+
Sbjct: 226 APEPSQKPPGKPCPGLAYEQRRCTGLPPCPV 256



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W PCSVTC  G   RY  C+  + +   +     +E        +QC  P    W  W
Sbjct: 84  STWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC-CPEMGGWSGW 142

Query: 419 VGAWNPCSKLC 429
            G W PCS  C
Sbjct: 143 -GPWEPCSVTC 152



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSR------TCG--AGVST 94
           P   G  C  D     +T +  T  P P DG W  W EWS C R      +C    G  +
Sbjct: 289 PQHGGPFCAGDA---TRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQS 345

Query: 95  QSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPI 128
           + R C   +   +G+ C G +   + C +   CP+
Sbjct: 346 RGRTCRGRK--FDGHRCAGQQQDIRHCYSIQHCPL 378



 Score = 37.9 bits (84), Expect = 0.077
 Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 6/84 (7%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--WVG 420
           W PCSVTC  G   R   C   H        C   +    +A   Q   P    W  W G
Sbjct: 145 WEPCSVTCSKGTRTRRRAC--NHPAPKCGGHCPG-QAQESEACDTQQVCPTHGAWATW-G 200

Query: 421 AWNPCSKLCHMPGEEVTKERSVYC 444
            W PCS  CH    E  + RS  C
Sbjct: 201 PWTPCSASCHGGPHEPKETRSRKC 224



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 3/34 (8%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           P  +PR   W  WS W+ CS TC  G   + R C
Sbjct: 74  PCRSPR---WSLWSTWAPCSVTCSEGSQLRYRRC 104


>AY297813-1|AAP43692.1|  469|Homo sapiens properdin P factor,
           complement protein.
          Length = 469

 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 46  PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           PG  C P +  + + C    P P    GGWGPW   S C  TCG G + + R CN+P P 
Sbjct: 234 PGKPC-PGLAYEQRRCTGLPPCPVA--GGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQ 290

Query: 106 NNGNYCIGDRSRYKVCNTD-PCPIN 129
           + G +C GD +R  +CNT  PCP++
Sbjct: 291 HGGPFCAGDATRTHICNTAVPCPVD 315



 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 45  APGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           APGT       C++Q C        P  GGW  W  W  CS TC  G  T+ R CN+P P
Sbjct: 116 APGTLEWQLQACEDQQC-------CPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAP 168

Query: 105 VNNGNYCIGDRSRYKVCNTDP-CP 127
              G +C G     + C+T   CP
Sbjct: 169 -KCGGHCPGQAQESEACDTQQVCP 191



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 8/91 (8%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAG----VSTQSRECN 100
           P   CG     Q Q   A  T    P  G W  W  W+ CS +C  G      T+SR+C+
Sbjct: 166 PAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS 225

Query: 101 NPEPVNN--GNYCIGDRSRYKVC-NTDPCPI 128
            PEP     G  C G     + C    PCP+
Sbjct: 226 APEPSQKPPGKPCPGLAYEQRRCTGLPPCPV 256



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W PCSVTC  G   RY  C+  + +   +     +E        +QC  P    W  W
Sbjct: 84  STWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC-CPEMGGWSGW 142

Query: 419 VGAWNPCSKLC 429
            G W PCS  C
Sbjct: 143 -GPWEPCSVTC 152



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSR------TCG--AGVST 94
           P   G  C  D     +T +  T  P P DG W  W EWS C R      +C    G  +
Sbjct: 289 PQHGGPFCAGDA---TRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQS 345

Query: 95  QSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPI 128
           + R C   +   +G+ C G +   + C +   CP+
Sbjct: 346 RGRTCRGRK--FDGHRCAGQQQDIRHCYSIQHCPL 378



 Score = 37.9 bits (84), Expect = 0.077
 Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 6/84 (7%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--WVG 420
           W PCSVTC  G   R   C   H        C   +    +A   Q   P    W  W G
Sbjct: 145 WEPCSVTCSKGTRTRRRAC--NHPAPKCGGHCPG-QAQESEACDTQQVCPTHGAWATW-G 200

Query: 421 AWNPCSKLCHMPGEEVTKERSVYC 444
            W PCS  CH    E  + RS  C
Sbjct: 201 PWTPCSASCHGGPHEPKETRSRKC 224



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 3/34 (8%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           P  +PR   W  WS W+ CS TC  G   + R C
Sbjct: 74  PCRSPR---WSLWSTWAPCSVTCSEGSQLRYRRC 104


>AL009172-3|CAA15658.1|  454|Homo sapiens complement factor
           properdin protein.
          Length = 454

 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 46  PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           PG  C P +  + + C    P P    GGWGPW   S C  TCG G + + R CN+P P 
Sbjct: 219 PGKPC-PGLAYEQRRCTGLPPCPVA--GGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQ 275

Query: 106 NNGNYCIGDRSRYKVCNTD-PCPIN 129
           + G +C GD +R  +CNT  PCP++
Sbjct: 276 HGGPFCAGDATRTHICNTAVPCPVD 300



 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 45  APGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           APGT       C++Q C        P  GGW  W  W  CS TC  G  T+ R CN+P P
Sbjct: 116 APGTLEWQLQACEDQQC-------CPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAP 168

Query: 105 VNNGNYCIGDRSRYKVCNTDP-CP 127
              G +C G     + C+T   CP
Sbjct: 169 -KCGGHCPGQAQESEACDTQQVCP 191



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W PCSVTC  G   RY  C+  + +   +     +E        +QC  P    W  W
Sbjct: 84  STWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC-CPEMGGWSGW 142

Query: 419 VGAWNPCSKLC 429
            G W PCS  C
Sbjct: 143 -GPWEPCSVTC 152



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSR------TCG--AGVST 94
           P   G  C  D     +T +  T  P P DG W  W EWS C R      +C    G  +
Sbjct: 274 PQHGGPFCAGDA---TRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQS 330

Query: 95  QSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPI 128
           + R C   +   +G+ C G +   + C +   CP+
Sbjct: 331 RGRTCRGRK--FDGHRCAGQQQDIRHCYSIQHCPL 363



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 3/34 (8%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           P  +PR   W  WS W+ CS TC  G   + R C
Sbjct: 74  PCRSPR---WSLWSTWAPCSVTCSEGSQLRYRRC 104


>AF005668-1|AAB62886.1|  469|Homo sapiens properdin protein.
          Length = 469

 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 46  PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           PG  C P +  + + C    P P    GGWGPW   S C  TCG G + + R CN+P P 
Sbjct: 234 PGKPC-PGLAYEQRRCTGLPPCPVA--GGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQ 290

Query: 106 NNGNYCIGDRSRYKVCNTD-PCPIN 129
           + G +C GD +R  +CNT  PCP++
Sbjct: 291 HGGPFCAGDATRTHICNTAVPCPVD 315



 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 45  APGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           APGT       C++Q C        P  GGW  W  W  CS TC  G  T+ R CN+P P
Sbjct: 116 APGTLEWQLQACEDQQC-------CPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAP 168

Query: 105 VNNGNYCIGDRSRYKVCNTDP-CP 127
              G +C G     + C+T   CP
Sbjct: 169 -KCGGHCPGQAQESEACDTQQVCP 191



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 8/91 (8%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAG----VSTQSRECN 100
           P   CG     Q Q   A  T    P  G W  W  W+ CS +C  G      T+SR+C+
Sbjct: 166 PAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS 225

Query: 101 NPEPVNN--GNYCIGDRSRYKVC-NTDPCPI 128
            PEP     G  C G     + C    PCP+
Sbjct: 226 APEPSQKPPGKPCPGLAYEQRRCTGLPPCPV 256



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W PCSVTC  G   RY  C+  + +   +     +E        +QC  P    W  W
Sbjct: 84  STWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC-CPEMGGWSGW 142

Query: 419 VGAWNPCSKLC 429
            G W PCS  C
Sbjct: 143 -GPWEPCSVTC 152



 Score = 39.1 bits (87), Expect = 0.033
 Identities = 27/93 (29%), Positives = 36/93 (38%), Gaps = 10/93 (10%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSR------TCGAGVSTQS 96
           P   G  C  D     +T +  T  P P DG W  W EWS C R      +C      QS
Sbjct: 289 PQHGGPFCAGDA---TRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGRQS 345

Query: 97  RECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPI 128
           R         +G+ C G +   + C +   CP+
Sbjct: 346 RGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPL 378



 Score = 37.9 bits (84), Expect = 0.077
 Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 6/84 (7%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--WVG 420
           W PCSVTC  G   R   C   H        C   +    +A   Q   P    W  W G
Sbjct: 145 WEPCSVTCSKGTRTRRRAC--NHPAPKCGGHCPG-QAQESEACDTQQVCPTHGAWATW-G 200

Query: 421 AWNPCSKLCHMPGEEVTKERSVYC 444
            W PCS  CH    E  + RS  C
Sbjct: 201 PWTPCSASCHGGPHEPKETRSRKC 224



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 3/34 (8%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           P  +PR   W  WS W+ CS TC  G   + R C
Sbjct: 74  PCRSPR---WSLWSTWAPCSVTCSEGSQLRYRRC 104


>AF005666-1|AAC51626.1|  469|Homo sapiens properdin protein.
          Length = 469

 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 46  PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           PG  C P +  + + C    P P    GGWGPW   S C  TCG G + + R CN+P P 
Sbjct: 234 PGKPC-PGLAYEQRRCTGLPPCPVA--GGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQ 290

Query: 106 NNGNYCIGDRSRYKVCNTD-PCPIN 129
           + G +C GD +R  +CNT  PCP++
Sbjct: 291 HGGPFCAGDATRTHICNTAVPCPVD 315



 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 45  APGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           APGT       C++Q C        P  GGW  W  W  CS TC  G  T+ R CN+P P
Sbjct: 116 APGTLEWQLQACEDQQC-------CPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAP 168

Query: 105 VNNGNYCIGDRSRYKVCNTDP-CP 127
              G +C G     + C+T   CP
Sbjct: 169 -KCGGHCPGQAQESEACDTQQVCP 191



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 8/91 (8%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAG----VSTQSRECN 100
           P   CG     Q Q   A  T    P  G W  W  W+ CS +C  G      T+SR+C+
Sbjct: 166 PAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS 225

Query: 101 NPEPVNN--GNYCIGDRSRYKVC-NTDPCPI 128
            PEP     G  C G     + C    PCP+
Sbjct: 226 APEPSQKPPGKPCPGLAYEQRRCTGLPPCPV 256



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W PCSVTC  G   RY  C+  + +   +     +E        +QC  P    W  W
Sbjct: 84  STWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC-CPEMGGWSGW 142

Query: 419 VGAWNPCSKLC 429
            G W PCS  C
Sbjct: 143 -GPWEPCSVTC 152



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSR------TCG--AGVST 94
           P   G  C  D     +T +  T  P P DG W  W EWS C R      +C    G  +
Sbjct: 289 PQHGGPFCAGDA---TRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQS 345

Query: 95  QSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPI 128
           + R C   +   +G+ C G +   + C +   CP+
Sbjct: 346 RGRTCRGRK--FDGHRCAGQQQDIRHCYSIQHCPL 378



 Score = 37.9 bits (84), Expect = 0.077
 Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 6/84 (7%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--WVG 420
           W PCSVTC  G   R   C   H        C   +    +A   Q   P    W  W G
Sbjct: 145 WEPCSVTCSKGTRTRRRAC--NHPAPKCGGHCPG-QAQESEACDTQQVCPTHGAWATW-G 200

Query: 421 AWNPCSKLCHMPGEEVTKERSVYC 444
            W PCS  CH    E  + RS  C
Sbjct: 201 PWTPCSASCHGGPHEPKETRSRKC 224



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 3/34 (8%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           P  +PR   W  WS W+ CS TC  G   + R C
Sbjct: 74  PCRSPR---WSLWSTWAPCSVTCSEGSQLRYRRC 104


>AF005665-1|AAB63280.1|  469|Homo sapiens properdin protein.
          Length = 469

 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 46  PGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           PG  C P +  + + C    P P    GGWGPW   S C  TCG G + + R CN+P P 
Sbjct: 234 PGKPC-PGLAYEQRRCTGLPPCPVA--GGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQ 290

Query: 106 NNGNYCIGDRSRYKVCNTD-PCPIN 129
           + G +C GD +R  +CNT  PCP++
Sbjct: 291 HGGPFCAGDATRTHICNTAVPCPVD 315



 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 45  APGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           APGT       C++Q C        P  GGW  W  W  CS TC  G  T+ R CN+P P
Sbjct: 116 APGTLEWQLQACEDQQC-------CPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAP 168

Query: 105 VNNGNYCIGDRSRYKVCNTDP-CP 127
              G +C G     + C+T   CP
Sbjct: 169 -KCGGHCPGQAQESEACDTQQVCP 191



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 8/91 (8%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAG----VSTQSRECN 100
           P   CG     Q Q   A  T    P  G W  W  W+ CS +C  G      T+SR+C+
Sbjct: 166 PAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCS 225

Query: 101 NPEPVNN--GNYCIGDRSRYKVC-NTDPCPI 128
            PEP     G  C G     + C    PCP+
Sbjct: 226 APEPSQKPPGKPCPGLAYEQRRCTGLPPCPV 256



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 14/95 (14%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSR------TCG--AGVST 94
           P   G  C  D     +T +  T  P P DG W  W EWS C R      +C    G  +
Sbjct: 289 PQHGGPFCAGDA---TRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQS 345

Query: 95  QSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPI 128
           + R C   +   +G+ C G +   + C +   CP+
Sbjct: 346 RGRTCRGRK--FDGHRCAGQQQDIRHCYSIQHCPL 378



 Score = 37.9 bits (84), Expect = 0.077
 Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 6/84 (7%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--WVG 420
           W PCSVTC  G   R   C   H        C   +    +A   Q   P    W  W G
Sbjct: 145 WEPCSVTCSKGTRTRRRAC--NHPAPKCGGHCPG-QAQESEACDTQQVCPTHGAWATW-G 200

Query: 421 AWNPCSKLCHMPGEEVTKERSVYC 444
            W PCS  CH    E  + RS  C
Sbjct: 201 PWTPCSASCHGGPHEPKETRSRKC 224



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 4/71 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W PCSVTC  G    Y  C+  + +   +     +E        +QC  P    W  W
Sbjct: 84  STWAPCSVTCSEGSQLWYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC-CPEMGGWSGW 142

Query: 419 VGAWNPCSKLC 429
            G W PCS  C
Sbjct: 143 -GPWEPCSVTC 152



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 12/29 (41%), Positives = 13/29 (44%)

Query: 71  RDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           R   W  WS W+ CS TC  G     R C
Sbjct: 76  RSPRWSLWSTWAPCSVTCSEGSQLWYRRC 104


>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone RP11-465I11 on chromosome 1. ).
          Length = 5635

 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 30/62 (48%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W PWS W  CSRTC  G   + R C+NP P N G  C G  S+ + CNTD CP
Sbjct: 4753 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812

Query: 128  IN 129
            ++
Sbjct: 4813 VD 4814



 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 43   PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            PA  G  C G D+  +N  C  +   P P DG W  WS W EC+R+CG G  T++R CNN
Sbjct: 4561 PANGGKPCQGSDLEMRN--CQNK---PCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNN 4615

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
            P   + G  C G+     +CN  PCP++
Sbjct: 4616 PSVQHGGRPCEGNAVEIIMCNIRPCPVH 4643



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43   PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 4789 PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 4843

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P PV  G  C GD ++   CN   CP
Sbjct: 4844 PVPVKGGRPCPGDTTQVTRCNVQACP 4869



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 28/62 (45%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W  W  W  CS +CG G  T++R CNNP P   G+YC G  ++ +VCN   CP
Sbjct: 4639 PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698

Query: 128  IN 129
            I+
Sbjct: 4699 IH 4700



 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 62   VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
            + R P      GG+  WS W  CS TCG G+  +SR CN P P N G  C G     + C
Sbjct: 4519 LVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNC 4578

Query: 122  NTDPCPIN 129
               PCP++
Sbjct: 4579 QNKPCPVD 4586



 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 43   PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            PA  G+ C      Q Q C  R     P  G W  W+ WS CS +CG G   ++R C++P
Sbjct: 4675 PAFGGSYCD-GAETQMQVCNERN---CPIHGKWATWASWSACSVSCGGGARQRTRGCSDP 4730

Query: 103  EPVNNGNYCIGDRSRYKVCNTDPCP 127
             P   G  C G   +   CN+DPCP
Sbjct: 4731 VPQYGGRKCEGSDVQSDFCNSDPCP 4755


>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-268N14 on chromosome 1. ).
          Length = 5635

 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 30/62 (48%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W PWS W  CSRTC  G   + R C+NP P N G  C G  S+ + CNTD CP
Sbjct: 4753 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812

Query: 128  IN 129
            ++
Sbjct: 4813 VD 4814



 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 43   PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            PA  G  C G D+  +N  C  +   P P DG W  WS W EC+R+CG G  T++R CNN
Sbjct: 4561 PANGGKPCQGSDLEMRN--CQNK---PCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNN 4615

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
            P   + G  C G+     +CN  PCP++
Sbjct: 4616 PSVQHGGRPCEGNAVEIIMCNIRPCPVH 4643



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43   PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 4789 PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 4843

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P PV  G  C GD ++   CN   CP
Sbjct: 4844 PVPVKGGRPCPGDTTQVTRCNVQACP 4869



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 28/62 (45%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W  W  W  CS +CG G  T++R CNNP P   G+YC G  ++ +VCN   CP
Sbjct: 4639 PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698

Query: 128  IN 129
            I+
Sbjct: 4699 IH 4700



 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 62   VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
            + R P      GG+  WS W  CS TCG G+  +SR CN P P N G  C G     + C
Sbjct: 4519 LVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNC 4578

Query: 122  NTDPCPIN 129
               PCP++
Sbjct: 4579 QNKPCPVD 4586



 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 43   PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            PA  G+ C      Q Q C  R     P  G W  W+ WS CS +CG G   ++R C++P
Sbjct: 4675 PAFGGSYCD-GAETQMQVCNERN---CPIHGKWATWASWSACSVSCGGGARQRTRGCSDP 4730

Query: 103  EPVNNGNYCIGDRSRYKVCNTDPCP 127
             P   G  C G   +   CN+DPCP
Sbjct: 4731 VPQYGGRKCEGSDVQSDFCNSDPCP 4755


>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-77J13 on chromosome 1. ).
          Length = 5635

 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 30/62 (48%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W PWS W  CSRTC  G   + R C+NP P N G  C G  S+ + CNTD CP
Sbjct: 4753 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812

Query: 128  IN 129
            ++
Sbjct: 4813 VD 4814



 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 43   PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            PA  G  C G D+  +N  C  +   P P DG W  WS W EC+R+CG G  T++R CNN
Sbjct: 4561 PANGGKPCQGSDLEMRN--CQNK---PCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNN 4615

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
            P   + G  C G+     +CN  PCP++
Sbjct: 4616 PSVQHGGRPCEGNAVEIIMCNIRPCPVH 4643



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43   PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 4789 PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 4843

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P PV  G  C GD ++   CN   CP
Sbjct: 4844 PVPVKGGRPCPGDTTQVTRCNVQACP 4869



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 28/62 (45%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W  W  W  CS +CG G  T++R CNNP P   G+YC G  ++ +VCN   CP
Sbjct: 4639 PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698

Query: 128  IN 129
            I+
Sbjct: 4699 IH 4700



 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 62   VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
            + R P      GG+  WS W  CS TCG G+  +SR CN P P N G  C G     + C
Sbjct: 4519 LVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNC 4578

Query: 122  NTDPCPIN 129
               PCP++
Sbjct: 4579 QNKPCPVD 4586



 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 43   PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            PA  G+ C      Q Q C  R     P  G W  W+ WS CS +CG G   ++R C++P
Sbjct: 4675 PAFGGSYCD-GAETQMQVCNERN---CPIHGKWATWASWSACSVSCGGGARQRTRGCSDP 4730

Query: 103  EPVNNGNYCIGDRSRYKVCNTDPCP 127
             P   G  C G   +   CN+DPCP
Sbjct: 4731 VPQYGGRKCEGSDVQSDFCNSDPCP 4755


>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-164L12 on chromosome 1. ).
          Length = 5635

 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 30/62 (48%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W PWS W  CSRTC  G   + R C+NP P N G  C G  S+ + CNTD CP
Sbjct: 4753 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812

Query: 128  IN 129
            ++
Sbjct: 4813 VD 4814



 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 43   PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            PA  G  C G D+  +N  C  +   P P DG W  WS W EC+R+CG G  T++R CNN
Sbjct: 4561 PANGGKPCQGSDLEMRN--CQNK---PCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNN 4615

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
            P   + G  C G+     +CN  PCP++
Sbjct: 4616 PSVQHGGRPCEGNAVEIIMCNIRPCPVH 4643



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43   PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 4789 PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 4843

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P PV  G  C GD ++   CN   CP
Sbjct: 4844 PVPVKGGRPCPGDTTQVTRCNVQACP 4869



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 28/62 (45%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W  W  W  CS +CG G  T++R CNNP P   G+YC G  ++ +VCN   CP
Sbjct: 4639 PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698

Query: 128  IN 129
            I+
Sbjct: 4699 IH 4700



 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 62   VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
            + R P      GG+  WS W  CS TCG G+  +SR CN P P N G  C G     + C
Sbjct: 4519 LVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNC 4578

Query: 122  NTDPCPIN 129
               PCP++
Sbjct: 4579 QNKPCPVD 4586



 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 43   PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            PA  G+ C      Q Q C  R     P  G W  W+ WS CS +CG G   ++R C++P
Sbjct: 4675 PAFGGSYCD-GAETQMQVCNERN---CPIHGKWATWASWSACSVSCGGGARQRTRGCSDP 4730

Query: 103  EPVNNGNYCIGDRSRYKVCNTDPCP 127
             P   G  C G   +   CN+DPCP
Sbjct: 4731 VPQYGGRKCEGSDVQSDFCNSDPCP 4755


>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-174L6 on chromosome 1. ).
          Length = 5635

 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 30/62 (48%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W PWS W  CSRTC  G   + R C+NP P N G  C G  S+ + CNTD CP
Sbjct: 4753 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812

Query: 128  IN 129
            ++
Sbjct: 4813 VD 4814



 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 43   PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            PA  G  C G D+  +N  C  +   P P DG W  WS W EC+R+CG G  T++R CNN
Sbjct: 4561 PANGGKPCQGSDLEMRN--CQNK---PCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNN 4615

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
            P   + G  C G+     +CN  PCP++
Sbjct: 4616 PSVQHGGRPCEGNAVEIIMCNIRPCPVH 4643



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43   PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 4789 PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 4843

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P PV  G  C GD ++   CN   CP
Sbjct: 4844 PVPVKGGRPCPGDTTQVTRCNVQACP 4869



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 28/62 (45%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W  W  W  CS +CG G  T++R CNNP P   G+YC G  ++ +VCN   CP
Sbjct: 4639 PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698

Query: 128  IN 129
            I+
Sbjct: 4699 IH 4700



 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 62   VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
            + R P      GG+  WS W  CS TCG G+  +SR CN P P N G  C G     + C
Sbjct: 4519 LVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNC 4578

Query: 122  NTDPCPIN 129
               PCP++
Sbjct: 4579 QNKPCPVD 4586



 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 43   PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            PA  G+ C      Q Q C  R     P  G W  W+ WS CS +CG G   ++R C++P
Sbjct: 4675 PAFGGSYCD-GAETQMQVCNERN---CPIHGKWATWASWSACSVSCGGGARQRTRGCSDP 4730

Query: 103  EPVNNGNYCIGDRSRYKVCNTDPCP 127
             P   G  C G   +   CN+DPCP
Sbjct: 4731 VPQYGGRKCEGSDVQSDFCNSDPCP 4755


>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-153O3 on chromosome 1. ).
          Length = 5635

 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 30/62 (48%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W PWS W  CSRTC  G   + R C+NP P N G  C G  S+ + CNTD CP
Sbjct: 4753 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812

Query: 128  IN 129
            ++
Sbjct: 4813 VD 4814



 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 43   PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            PA  G  C G D+  +N  C  +   P P DG W  WS W EC+R+CG G  T++R CNN
Sbjct: 4561 PANGGKPCQGSDLEMRN--CQNK---PCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNN 4615

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
            P   + G  C G+     +CN  PCP++
Sbjct: 4616 PSVQHGGRPCEGNAVEIIMCNIRPCPVH 4643



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43   PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 4789 PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 4843

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P PV  G  C GD ++   CN   CP
Sbjct: 4844 PVPVKGGRPCPGDTTQVTRCNVQACP 4869



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 28/62 (45%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W  W  W  CS +CG G  T++R CNNP P   G+YC G  ++ +VCN   CP
Sbjct: 4639 PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698

Query: 128  IN 129
            I+
Sbjct: 4699 IH 4700



 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 62   VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
            + R P      GG+  WS W  CS TCG G+  +SR CN P P N G  C G     + C
Sbjct: 4519 LVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNC 4578

Query: 122  NTDPCPIN 129
               PCP++
Sbjct: 4579 QNKPCPVD 4586



 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 43   PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            PA  G+ C      Q Q C  R     P  G W  W+ WS CS +CG G   ++R C++P
Sbjct: 4675 PAFGGSYCD-GAETQMQVCNERN---CPIHGKWATWASWSACSVSCGGGARQRTRGCSDP 4730

Query: 103  EPVNNGNYCIGDRSRYKVCNTDPCP 127
             P   G  C G   +   CN+DPCP
Sbjct: 4731 VPQYGGRKCEGSDVQSDFCNSDPCP 4755


>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
          Length = 5635

 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 30/62 (48%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W PWS W  CSRTC  G   + R C+NP P N G  C G  S+ + CNTD CP
Sbjct: 4753 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812

Query: 128  IN 129
            ++
Sbjct: 4813 VD 4814



 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 43   PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            PA  G  C G D+  +N  C  +   P P DG W  WS W EC+R+CG G  T++R CNN
Sbjct: 4561 PANGGKPCQGSDLEMRN--CQNK---PCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNN 4615

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
            P   + G  C G+     +CN  PCP++
Sbjct: 4616 PSVQHGGRPCEGNAVEIIMCNIRPCPVH 4643



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43   PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 4789 PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 4843

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P PV  G  C GD ++   CN   CP
Sbjct: 4844 PVPVKGGRPCPGDTTQVTRCNVQACP 4869



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 28/62 (45%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W  W  W  CS +CG G  T++R CNNP P   G+YC G  ++ +VCN   CP
Sbjct: 4639 PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698

Query: 128  IN 129
            I+
Sbjct: 4699 IH 4700



 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 62   VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
            + R P      GG+  WS W  CS TCG G+  +SR CN P P N G  C G     + C
Sbjct: 4519 LVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNC 4578

Query: 122  NTDPCPIN 129
               PCP++
Sbjct: 4579 QNKPCPVD 4586



 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 43   PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            PA  G+ C      Q Q C  R     P  G W  W+ WS CS +CG G   ++R C++P
Sbjct: 4675 PAFGGSYCD-GAETQMQVCNERN---CPIHGKWATWASWSACSVSCGGGARQRTRGCSDP 4730

Query: 103  EPVNNGNYCIGDRSRYKVCNTDPCP 127
             P   G  C G   +   CN+DPCP
Sbjct: 4731 VPQYGGRKCEGSDVQSDFCNSDPCP 4755


>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
          Length = 5635

 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 30/62 (48%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W PWS W  CSRTC  G   + R C+NP P N G  C G  S+ + CNTD CP
Sbjct: 4753 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812

Query: 128  IN 129
            ++
Sbjct: 4813 VD 4814



 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 43   PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            PA  G  C G D+  +N  C  +   P P DG W  WS W EC+R+CG G  T++R CNN
Sbjct: 4561 PANGGKPCQGSDLEMRN--CQNK---PCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNN 4615

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
            P   + G  C G+     +CN  PCP++
Sbjct: 4616 PSVQHGGRPCEGNAVEIIMCNIRPCPVH 4643



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43   PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 4789 PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 4843

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P PV  G  C GD ++   CN   CP
Sbjct: 4844 PVPVKGGRPCPGDTTQVTRCNVQACP 4869



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 28/62 (45%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W  W  W  CS +CG G  T++R CNNP P   G+YC G  ++ +VCN   CP
Sbjct: 4639 PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698

Query: 128  IN 129
            I+
Sbjct: 4699 IH 4700



 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 62   VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
            + R P      GG+  WS W  CS TCG G+  +SR CN P P N G  C G     + C
Sbjct: 4519 LVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNC 4578

Query: 122  NTDPCPIN 129
               PCP++
Sbjct: 4579 QNKPCPVD 4586



 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 43   PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            PA  G+ C      Q Q C  R     P  G W  W+ WS CS +CG G   ++R C++P
Sbjct: 4675 PAFGGSYCD-GAETQMQVCNERN---CPIHGKWATWASWSACSVSCGGGARQRTRGCSDP 4730

Query: 103  EPVNNGNYCIGDRSRYKVCNTDPCP 127
             P   G  C G   +   CN+DPCP
Sbjct: 4731 VPQYGGRKCEGSDVQSDFCNSDPCP 4755


>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
          Length = 2673

 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 30/62 (48%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W PWS W  CSRTC  G   + R C+NP P N G  C G  S+ + CNTD CP
Sbjct: 1791 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 1850

Query: 128  IN 129
            ++
Sbjct: 1851 VD 1852



 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 43   PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            PA  G  C G D+  +N  C  +   P P DG W  WS W EC+R+CG G  T++R CNN
Sbjct: 1599 PANGGKPCQGSDLEMRN--CQNK---PCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNN 1653

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
            P   + G  C G+     +CN  PCP++
Sbjct: 1654 PSVQHGGRPCEGNAVEIIMCNIRPCPVH 1681



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43   PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 1827 PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 1881

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P PV  G  C GD ++   CN   CP
Sbjct: 1882 PVPVKGGRPCPGDTTQVTRCNVQACP 1907



 Score = 76.6 bits (180), Expect = 2e-13
 Identities = 27/62 (43%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W  W  W  CS +CG G  T++R CNNP P   G+YC G  ++ +VCN   CP
Sbjct: 1677 PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 1736

Query: 128  IN 129
            ++
Sbjct: 1737 VH 1738



 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 62   VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
            + R P      GG+  WS W  CS TCG G+  +SR CN P P N G  C G     + C
Sbjct: 1557 LVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNC 1616

Query: 122  NTDPCPIN 129
               PCP++
Sbjct: 1617 QNKPCPVD 1624



 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 43   PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            PA  G+ C      Q Q C  R     P  G W  W+ WS CS +CG G   ++R C++P
Sbjct: 1713 PAFGGSYCD-GAETQMQVCNERN---CPVHGKWATWASWSACSVSCGGGARQRTRGCSDP 1768

Query: 103  EPVNNGNYCIGDRSRYKVCNTDPCP 127
             P   G  C G   +   CN+DPCP
Sbjct: 1769 VPQYGGRKCEGSDVQSDFCNSDPCP 1793


>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
          Length = 5636

 Score = 79.4 bits (187), Expect = 3e-14
 Identities = 30/62 (48%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W PWS W  CSRTC  G   + R C+NP P N G  C G  S+ + CNTD CP
Sbjct: 4754 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4813

Query: 128  IN 129
            ++
Sbjct: 4814 VD 4815



 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 43   PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            PA  G  C G D+  +N  C  +   P P DG W  WS W EC+R+CG G  T++R CNN
Sbjct: 4562 PANGGKPCQGSDLEMRN--CQNK---PCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNN 4616

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
            P   + G  C G+     +CN  PCP++
Sbjct: 4617 PSVQHGGRPCEGNAVEIIMCNIRPCPVH 4644



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43   PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
            P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 4790 PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 4844

Query: 102  PEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P PV  G  C GD ++   CN   CP
Sbjct: 4845 PVPVKGGRPCPGDTTQVTRCNVQACP 4870



 Score = 77.0 bits (181), Expect = 1e-13
 Identities = 28/62 (45%), Positives = 36/62 (58%)

Query: 68   PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            P P  G W  W  W  CS +CG G  T++R CNNP P   G+YC G  ++ +VCN   CP
Sbjct: 4640 PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4699

Query: 128  IN 129
            I+
Sbjct: 4700 IH 4701



 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 62   VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
            + R P      GG+  WS W  CS TCG G+  +SR CN P P N G  C G     + C
Sbjct: 4520 LVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNC 4579

Query: 122  NTDPCPIN 129
               PCP++
Sbjct: 4580 QNKPCPVD 4587



 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 43   PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
            PA  G+ C      Q Q C  R     P  G W  W+ WS CS +CG G   ++R C++P
Sbjct: 4676 PAFGGSYCD-GAETQMQVCNERN---CPIHGKWATWASWSACSVSCGGGARQRTRGCSDP 4731

Query: 103  EPVNNGNYCIGDRSRYKVCNTDPCP 127
             P   G  C G   +   CN+DPCP
Sbjct: 4732 VPQYGGRKCEGSDVQSDFCNSDPCP 4756


>BC077726-1|AAH77726.1| 1151|Homo sapiens sema domain, seven
           thrombospondin repeats (type 1 and type 1-like),
           transmembra protein.
          Length = 1151

 Score = 78.6 bits (185), Expect = 4e-14
 Identities = 34/86 (39%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
           PA    +C  D   ++      T SP    GGW  W  WS CSR C  G   + R C NP
Sbjct: 825 PADGSGSCDTDALVEDLLRSGST-SPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNP 883

Query: 103 EPVNNGNYCIGDRSRYKVCNTDPCPI 128
           EP N G  C+GD + Y+ CN   CP+
Sbjct: 884 EPRNGGLPCVGDAAEYQDCNPQACPV 909



 Score = 70.9 bits (166), Expect = 9e-12
 Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 1/59 (1%)

Query: 71  RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD-PCPI 128
           R+G W PWS W+ CS +CG G   + R C+NP P + G  C+G     + CN + PCP+
Sbjct: 663 RNGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPV 721



 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 5/111 (4%)

Query: 17  GLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWG 76
           G  S  S  CE  + +    CT    P   G  C  D   + Q C    P   P  G W 
Sbjct: 860 GPWSSCSRDCELGFRVRKRTCTNP-EPRNGGLPCVGDA-AEYQDC---NPQACPVRGAWS 914

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            W+ WS CS +CG G   ++R C +P P    + C+G  +   +C T  CP
Sbjct: 915 CWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACP 965



 Score = 60.5 bits (140), Expect = 1e-08
 Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 8/71 (11%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
           + + C   TP P P    W  W  WS+CS  CG G+ ++ R C       NGN C+G   
Sbjct: 709 EERFCNENTPCPVPIF--WASWGSWSKCSSNCGGGMQSRRRAC------ENGNSCLGCGV 760

Query: 117 RYKVCNTDPCP 127
            +K CN + CP
Sbjct: 761 EFKTCNPEGCP 771



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 54  MWCQNQT-CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVST---QSRECNNPEPVNNGN 109
           +W QN T C  R  +   RDGG+GPWS W  C    G    +   ++R C++P P   G 
Sbjct: 593 LWTQNITACPVRNVT---RDGGFGPWSPWQPCEHLDGDNSGSCLCRARSCDSPRPRCGGL 649

Query: 110 YCIGDRSRYKVCN 122
            C+G       C+
Sbjct: 650 DCLGPAIHIANCS 662



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%)

Query: 74   GWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPS 132
            GW PWSEWS+C+     G  ++SR C   E +   + C G+ S+ + C     P+  P+
Sbjct: 967  GWSPWSEWSKCT---DDGAQSRSRHCE--ELLPGSSACAGNSSQSRPCPYSEIPVILPA 1020



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 1/69 (1%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W  CS +CG+G+  R   C +   R   +         R       C  P     W G
Sbjct: 671 SSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVPIFWASW-G 729

Query: 421 AWNPCSKLC 429
           +W+ CS  C
Sbjct: 730 SWSKCSSNC 738


>AB040878-1|BAA95969.1| 1202|Homo sapiens KIAA1445 protein protein.
          Length = 1202

 Score = 78.6 bits (185), Expect = 4e-14
 Identities = 34/86 (39%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
           PA    +C  D   ++      T SP    GGW  W  WS CSR C  G   + R C NP
Sbjct: 876 PADGSGSCDTDALVEDLLRSGST-SPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNP 934

Query: 103 EPVNNGNYCIGDRSRYKVCNTDPCPI 128
           EP N G  C+GD + Y+ CN   CP+
Sbjct: 935 EPRNGGLPCVGDAAEYQDCNPQACPV 960



 Score = 70.9 bits (166), Expect = 9e-12
 Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 1/59 (1%)

Query: 71  RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD-PCPI 128
           R+G W PWS W+ CS +CG G   + R C+NP P + G  C+G     + CN + PCP+
Sbjct: 714 RNGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPV 772



 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 5/111 (4%)

Query: 17   GLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWG 76
            G  S  S  CE  + +    CT    P   G  C  D   + Q C    P   P  G W 
Sbjct: 911  GPWSSCSRDCELGFRVRKRTCTNP-EPRNGGLPCVGDA-AEYQDC---NPQACPVRGAWS 965

Query: 77   PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
             W+ WS CS +CG G   ++R C +P P    + C+G  +   +C T  CP
Sbjct: 966  CWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACP 1016



 Score = 60.5 bits (140), Expect = 1e-08
 Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 8/71 (11%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
           + + C   TP P P    W  W  WS+CS  CG G+ ++ R C       NGN C+G   
Sbjct: 760 EERFCNENTPCPVPIF--WASWGSWSKCSSNCGGGMQSRRRAC------ENGNSCLGCGV 811

Query: 117 RYKVCNTDPCP 127
            +K CN + CP
Sbjct: 812 EFKTCNPEGCP 822



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 54  MWCQNQT-CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVST---QSRECNNPEPVNNGN 109
           +W QN T C  R  +   RDGG+GPWS W  C    G    +   ++R C++P P   G 
Sbjct: 644 LWTQNITACPVRNVT---RDGGFGPWSPWQPCEHLDGDNSGSCLCRARSCDSPRPRCGGL 700

Query: 110 YCIGDRSRYKVCN 122
            C+G       C+
Sbjct: 701 DCLGPAIHIANCS 713



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%)

Query: 74   GWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPS 132
            GW PWSEWS+C+     G  ++SR C   E +   + C G+ S+ + C     P+  P+
Sbjct: 1018 GWSPWSEWSKCT---DDGAQSRSRHCE--ELLPGSSACAGNSSQSRPCPYSEIPVILPA 1071



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 1/69 (1%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W  CS +CG+G+  R   C +   R   +         R       C  P     W G
Sbjct: 722 SSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVPIFWASW-G 780

Query: 421 AWNPCSKLC 429
           +W+ CS  C
Sbjct: 781 SWSKCSSNC 789


>U52840-1|AAC09473.1| 1074|Homo sapiens semaphorin F homolog
           protein.
          Length = 1074

 Score = 77.8 bits (183), Expect = 8e-14
 Identities = 35/86 (40%), Positives = 46/86 (53%), Gaps = 6/86 (6%)

Query: 43  PAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
           P   G  C GP +  + Q C      P P DG W  WS W++CS TCG G   ++R C+N
Sbjct: 816 PKYGGMPCLGPSL--EYQEC---NTLPCPVDGVWSCWSPWTKCSATCGGGHYMRTRSCSN 870

Query: 102 PEPVNNGNYCIGDRSRYKVCNTDPCP 127
           P P   G+ C+G  +   +CNT PCP
Sbjct: 871 PAPAYGGDICLGLHTEEALCNTQPCP 896



 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 27/58 (46%), Positives = 36/58 (62%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +G W  W+ WS+CSR C  G+  + R CNNPEP   G  C+G    Y+ CNT PCP++
Sbjct: 784 NGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNTLPCPVD 841



 Score = 70.5 bits (165), Expect = 1e-11
 Identities = 24/52 (46%), Positives = 31/52 (59%)

Query: 71  RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCN 122
           R+GGW PW+ WS CS TCG G   + R C+NP P + G  C+G     + CN
Sbjct: 594 RNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCN 645



 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 6/53 (11%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           W  W  W  C+  CG G+  + R C       NG  C G    Y+ CNT+PCP
Sbjct: 656 WTGWGPWERCTAQCGGGIQARRRIC------ENGPDCAGCNVEYQSCNTNPCP 702



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 3/54 (5%)

Query: 72  DGGWGPWSEWSECSRTCGAGVST---QSRECNNPEPVNNGNYCIGDRSRYKVCN 122
           DG +G WS W+ C+ T G+ V +   ++R C++P P   G  C G       C+
Sbjct: 540 DGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCS 593



 Score = 37.5 bits (83), Expect = 0.10
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P    W  WS+WSEC     +GV  ++R+C    P+  G+ C G+ +  + C  D   I 
Sbjct: 894 PCPESWSEWSDWSECE---ASGVQVRARQCILLFPM--GSQCSGNTTESRPCVFDSNFIP 948

Query: 130 EPS 132
           E S
Sbjct: 949 EVS 951



 Score = 33.1 bits (72), Expect = 2.2
 Identities = 10/21 (47%), Positives = 14/21 (66%)

Query: 361 SEWTPCSVTCGVGYTRRYYEC 381
           + W+PCS TCG+G+  R   C
Sbjct: 602 TSWSPCSTTCGIGFQVRQRSC 622


>BC115696-1|AAI15697.1| 1074|Homo sapiens sema domain, seven
           thrombospondin repeats (type 1 and type 1-like),
           transmembra protein.
          Length = 1074

 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 28/60 (46%), Positives = 37/60 (61%)

Query: 68  PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           P P DG W  WS W++CS TCG G   ++R C+NP P   G+ C+G  +   +CNT PCP
Sbjct: 837 PCPVDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCP 896



 Score = 74.9 bits (176), Expect = 5e-13
 Identities = 26/58 (44%), Positives = 35/58 (60%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +G W  W+ WS+CSR C  G+  + R CNNPEP   G  C+G    Y+ CN  PCP++
Sbjct: 784 NGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPVD 841



 Score = 70.5 bits (165), Expect = 1e-11
 Identities = 24/52 (46%), Positives = 31/52 (59%)

Query: 71  RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCN 122
           R+GGW PW+ WS CS TCG G   + R C+NP P + G  C+G     + CN
Sbjct: 594 RNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCN 645



 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 6/53 (11%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           W  W  W  C+  CG G+  + R C       NG  C G    Y+ CNT+PCP
Sbjct: 656 WTGWGPWERCTAQCGGGIQARRRIC------ENGPDCAGCNVEYQSCNTNPCP 702



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 3/54 (5%)

Query: 72  DGGWGPWSEWSECSRTCGAGVST---QSRECNNPEPVNNGNYCIGDRSRYKVCN 122
           DG +G WS W+ C+ T G+ V +   ++R C++P P   G  C G       C+
Sbjct: 540 DGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCS 593



 Score = 37.5 bits (83), Expect = 0.10
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P    W  WS+WSEC     +GV  ++R+C    P+  G+ C G+ +  + C  D   I 
Sbjct: 894 PCPESWSEWSDWSECE---ASGVQVRARQCILLFPM--GSQCSGNTTESRPCVFDSNFIP 948

Query: 130 EPS 132
           E S
Sbjct: 949 EVS 951



 Score = 33.1 bits (72), Expect = 2.2
 Identities = 10/21 (47%), Positives = 14/21 (66%)

Query: 361 SEWTPCSVTCGVGYTRRYYEC 381
           + W+PCS TCG+G+  R   C
Sbjct: 602 TSWSPCSTTCGIGFQVRQRSC 622


>AY358124-1|AAQ88491.1| 1092|Homo sapiens SEMA5B protein.
          Length = 1092

 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 29/62 (46%), Positives = 34/62 (54%)

Query: 67  SPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           SP    GGW  W  WS CSR C  G   + R C NPEP N G  C+GD + Y+ CN   C
Sbjct: 847 SPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQAC 906

Query: 127 PI 128
           P+
Sbjct: 907 PV 908



 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 1/59 (1%)

Query: 71  RDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD-PCPI 128
           R+G W PWS W+ CS +CG G   + R C+NP P + G   +G     + CN + PCP+
Sbjct: 663 RNGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRIFVGKSREERFCNENTPCPV 721



 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 5/111 (4%)

Query: 17  GLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWG 76
           G  S  S  CE  + +    CT    P   G  C  D   + Q C    P   P  G W 
Sbjct: 859 GPWSSCSRDCELGFRVRKRTCTNP-EPRNGGLPCVGDA-AEYQDC---NPQACPVRGAWS 913

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
            W+ WS CS +CG G   ++R C +P P    + C+G  +   +C T  CP
Sbjct: 914 CWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACP 964



 Score = 57.6 bits (133), Expect = 9e-08
 Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 9/71 (12%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRS 116
           + + C   TP P P    W  W  WS+CS  CG G+ ++ R C       NGN C+G   
Sbjct: 709 EERFCNENTPCPVPIF--WASWGSWSKCSSNCGGGMQSRRRAC------ENGNSCLG-CG 759

Query: 117 RYKVCNTDPCP 127
            +K CN + CP
Sbjct: 760 EFKTCNPEGCP 770



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 54  MWCQNQT-CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVST---QSRECNNPEPVNNGN 109
           +W QN T C  R  +   RDGG+GPWS W  C    G    +   ++R C++P P   G 
Sbjct: 593 LWTQNITACPVRNVT---RDGGFGPWSPWQPCEHLDGDNSGSCLCRARSCDSPRPRCGGL 649

Query: 110 YCIGDRSRYKVCN 122
            C+G       C+
Sbjct: 650 DCLGPAIHIANCS 662



 Score = 44.0 bits (99), Expect = 0.001
 Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 8/76 (10%)

Query: 74   GWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEP-- 131
            GW PWSEWS+C+     G  ++SR C   E +   + C G+ S+ + C     P+  P  
Sbjct: 965  GWSPWSEWSKCT---DDGAQSRSRHCE--ELLPGSSACAGNSSQSRPCPYSEIPVILPAS 1019

Query: 132  SFRE-VQCSRHNNMPY 146
            S  E   C+   N  Y
Sbjct: 1020 SMEEATDCAGKRNRTY 1035



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 18/71 (25%), Positives = 30/71 (42%), Gaps = 5/71 (7%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W  CS +CG+G+  R   C +   R     + +  +    +   +    P  + W  W
Sbjct: 671 SSWALCSTSCGIGFQVRQRSCSNPAPR--HGGRIFVGKSREERFCNENTPCPVPIFWASW 728

Query: 419 VGAWNPCSKLC 429
            G+W+ CS  C
Sbjct: 729 -GSWSKCSSNC 738


>AK027344-1|BAB55049.1|  741|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14438 fis, clone HEMBB1000317, weakly similar to
           FIBULIN-1, ISOFORM D PRECURSOR. ).
          Length = 741

 Score = 77.4 bits (182), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 43  PAAPGTTCG-PDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
           P+  G  CG PD   Q Q C        P DG WG W  WS+CS +CG G  T+ R C++
Sbjct: 12  PSNGGRACGGPDS--QIQRC---NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDH 66

Query: 102 PEPVNNGNYCIGDRSRYKVCNTDPCP 127
           P PV  G  C GD ++   CN   CP
Sbjct: 67  PVPVKGGRPCPGDTTQVTRCNVQACP 92



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 16/33 (48%), Positives = 21/33 (63%)

Query: 97  RECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           R C+NP P N G  C G  S+ + CNTD CP++
Sbjct: 5   RTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVD 37


>AY358351-1|AAQ88717.1|  945|Homo sapiens GARS1883 protein.
          Length = 945

 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS CS  CG G   ++R C NP P+N G +C G   +   C T  CP++
Sbjct: 246 NGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTT-ICPVD 302



 Score = 52.8 bits (121), Expect = 3e-06
 Identities = 36/116 (31%), Positives = 43/116 (37%), Gaps = 9/116 (7%)

Query: 20  SKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWS 79
           S  S  C   W      CT    P   G  C    + Q   C     +  P DG W  WS
Sbjct: 256 SPCSNRCGRGWQKRTRTCTNPA-PLNGGAFCEGQAF-QKTACT----TICPVDGAWTEWS 309

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFRE 135
           +WS CS  C      +SREC  P P N G  C G     K C    C  N+ +  +
Sbjct: 310 KWSACSTEC---AHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKTLSD 362


>AY126437-1|AAM95701.1|  934|Homo sapiens transmembrane receptor
           UNC5H2 protein.
          Length = 934

 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS CS  CG G   ++R C NP P+N G +C G   +   C T  CP++
Sbjct: 246 NGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTT-ICPVD 302



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 35/107 (32%), Positives = 39/107 (36%), Gaps = 9/107 (8%)

Query: 20  SKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWS 79
           S  S  C   W      CT    P   G  C    + Q   C     +  P DG W  WS
Sbjct: 256 SPCSNRCGRGWQKRTRTCTNPA-PLNGGAFCEGQAF-QKTACT----TICPVDGAWTEWS 309

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           +WS CS  C      +SREC  P P N G  C G     K C    C
Sbjct: 310 KWSACSTEC---AHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLC 353


>AL359832-2|CAI16738.1|  934|Homo sapiens unc-5 homolog B (C.
           elegans) protein.
          Length = 934

 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS CS  CG G   ++R C NP P+N G +C G   +   C T  CP++
Sbjct: 246 NGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTT-ICPVD 302



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 35/107 (32%), Positives = 39/107 (36%), Gaps = 9/107 (8%)

Query: 20  SKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWS 79
           S  S  C   W      CT    P   G  C    + Q   C     +  P DG W  WS
Sbjct: 256 SPCSNRCGRGWQKRTRTCTNPA-PLNGGAFCEGQAF-QKTACT----TICPVDGAWTEWS 309

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           +WS CS  C      +SREC  P P N G  C G     K C    C
Sbjct: 310 KWSACSTEC---AHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLC 353


>AL359832-1|CAI16737.1|  945|Homo sapiens unc-5 homolog B (C.
           elegans) protein.
          Length = 945

 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS CS  CG G   ++R C NP P+N G +C G   +   C T  CP++
Sbjct: 246 NGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTT-ICPVD 302



 Score = 52.8 bits (121), Expect = 3e-06
 Identities = 36/116 (31%), Positives = 43/116 (37%), Gaps = 9/116 (7%)

Query: 20  SKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWS 79
           S  S  C   W      CT    P   G  C    + Q   C     +  P DG W  WS
Sbjct: 256 SPCSNRCGRGWQKRTRTCTNPA-PLNGGAFCEGQAF-QKTACT----TICPVDGAWTEWS 309

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFRE 135
           +WS CS  C      +SREC  P P N G  C G     K C    C  N+ +  +
Sbjct: 310 KWSACSTEC---AHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKTLSD 362


>AL359384-3|CAI16090.1|  934|Homo sapiens unc-5 homolog B (C.
           elegans) protein.
          Length = 934

 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS CS  CG G   ++R C NP P+N G +C G   +   C T  CP++
Sbjct: 246 NGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTT-ICPVD 302



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 35/107 (32%), Positives = 39/107 (36%), Gaps = 9/107 (8%)

Query: 20  SKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWS 79
           S  S  C   W      CT    P   G  C    + Q   C     +  P DG W  WS
Sbjct: 256 SPCSNRCGRGWQKRTRTCTNPA-PLNGGAFCEGQAF-QKTACT----TICPVDGAWTEWS 309

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           +WS CS  C      +SREC  P P N G  C G     K C    C
Sbjct: 310 KWSACSTEC---AHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLC 353


>AL359384-2|CAI16089.1|  945|Homo sapiens unc-5 homolog B (C.
           elegans) protein.
          Length = 945

 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS CS  CG G   ++R C NP P+N G +C G   +   C T  CP++
Sbjct: 246 NGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTT-ICPVD 302



 Score = 52.8 bits (121), Expect = 3e-06
 Identities = 36/116 (31%), Positives = 43/116 (37%), Gaps = 9/116 (7%)

Query: 20  SKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWS 79
           S  S  C   W      CT    P   G  C    + Q   C     +  P DG W  WS
Sbjct: 256 SPCSNRCGRGWQKRTRTCTNPA-PLNGGAFCEGQAF-QKTACT----TICPVDGAWTEWS 309

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFRE 135
           +WS CS  C      +SREC  P P N G  C G     K C    C  N+ +  +
Sbjct: 310 KWSACSTEC---AHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKTLSD 362


>AB096256-1|BAC57998.1|  945|Homo sapiens p53-regulated receptor for
           death and life protein.
          Length = 945

 Score = 67.3 bits (157), Expect = 1e-10
 Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS CS  CG G   ++R C NP P+N G +C G   +   C T  CP++
Sbjct: 246 NGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTT-ICPVD 302



 Score = 52.8 bits (121), Expect = 3e-06
 Identities = 36/116 (31%), Positives = 43/116 (37%), Gaps = 9/116 (7%)

Query: 20  SKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWS 79
           S  S  C   W      CT    P   G  C    + Q   C     +  P DG W  WS
Sbjct: 256 SPCSNRCGRGWQKRTRTCTNPA-PLNGGAFCEGQAF-QKTACT----TICPVDGAWTEWS 309

Query: 80  EWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFRE 135
           +WS CS  C      +SREC  P P N G  C G     K C    C  N+ +  +
Sbjct: 310 KWSACSTEC---AHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKTLSD 362


>BC041156-1|AAH41156.1|  597|Homo sapiens UNC5C protein protein.
          Length = 597

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 25/58 (43%), Positives = 36/58 (62%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS C+  CG G   ++R C NP P+N G +C G +S  K+  T  CP++
Sbjct: 260 NGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEG-QSVQKIACTTLCPVD 316



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 3/57 (5%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           P DG W PWS+WS C   C      + REC  P P N G  C G   + K C    C
Sbjct: 314 PVDGRWTPWSKWSTCGTEC---THWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLC 367


>AF055634-1|AAC67491.1|  931|Homo sapiens transmembrane receptor
           UNC5C protein.
          Length = 931

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 25/58 (43%), Positives = 36/58 (62%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS C+  CG G   ++R C NP P+N G +C G +S  K+  T  CP++
Sbjct: 260 NGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEG-QSVQKIACTTLCPVD 316



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 3/67 (4%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W PWS+WS C   C      + REC  P P N G  C G   + K C    C   
Sbjct: 314 PVDGRWTPWSKWSTCGTEC---THWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQT 370

Query: 130 EPSFREV 136
            P   +V
Sbjct: 371 APDSDDV 377


>AC098584-1|AAY41022.1|  506|Homo sapiens unknown protein.
          Length = 506

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 25/58 (43%), Positives = 36/58 (62%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS C+  CG G   ++R C NP P+N G +C G +S  K+  T  CP++
Sbjct: 218 NGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEG-QSVQKIACTTLCPVD 274



 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 3/67 (4%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W PWS+WS C   C      + REC  P P N G  C G   + K C    C   
Sbjct: 272 PVDGRWTPWSKWSTCGTEC---THWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQT 328

Query: 130 EPSFREV 136
            P   +V
Sbjct: 329 APDSDDV 335


>AY358147-1|AAQ88514.1|  953|Homo sapiens UNC5D protein.
          Length = 953

 Score = 65.7 bits (153), Expect = 3e-10
 Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS C+  CG G   +SR C NP P+N G +C G  S  K+  T  CP++
Sbjct: 252 NGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEG-MSVQKITCTSLCPVD 308



 Score = 56.4 bits (130), Expect = 2e-07
 Identities = 36/112 (32%), Positives = 44/112 (39%), Gaps = 9/112 (8%)

Query: 26  CEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECS 85
           C   W      CT    P   G  C   M  Q  TC     S  P DG W  WSEWS CS
Sbjct: 268 CGRGWQKRSRTCTNPA-PLNGGAFC-EGMSVQKITCT----SLCPVDGSWEVWSEWSVCS 321

Query: 86  RTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQ 137
             C      + REC  P P N G +C G     + C    C +++    E++
Sbjct: 322 PEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIK 370


>AB055056-1|BAB83663.1|  948|Homo sapiens KIAA1777 protein (Unc5h4)
           protein.
          Length = 948

 Score = 65.7 bits (153), Expect = 3e-10
 Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 1/58 (1%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           +GGW  W+EWS C+  CG G   +SR C NP P+N G +C G  S  K+  T  CP++
Sbjct: 247 NGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEG-MSVQKITCTSLCPVD 303



 Score = 56.4 bits (130), Expect = 2e-07
 Identities = 36/112 (32%), Positives = 44/112 (39%), Gaps = 9/112 (8%)

Query: 26  CEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECS 85
           C   W      CT    P   G  C   M  Q  TC     S  P DG W  WSEWS CS
Sbjct: 263 CGRGWQKRSRTCTNPA-PLNGGAFC-EGMSVQKITCT----SLCPVDGSWEVWSEWSVCS 316

Query: 86  RTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQ 137
             C      + REC  P P N G +C G     + C    C +++    E++
Sbjct: 317 PEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIK 365


>AK023228-1|BAB14479.1|  622|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13166 fis, clone NT2RP3003701, weakly similar to
           F-SPONDIN PRECURSOR. ).
          Length = 622

 Score = 64.5 bits (150), Expect = 8e-10
 Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 11/111 (9%)

Query: 366 CSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAWNPC 425
           CSV+CG G   RY  C D   R+ ++S C H+  P   A +  C  P C  W  G W+PC
Sbjct: 282 CSVSCGRGTQARYVSCRDALDRIADESYCAHLPRP---AEIWDCFTP-CGEWQAGDWSPC 337

Query: 426 SKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
           S  C   G   T  R V C++    + +D++ C   ++P+   +C+ + AC
Sbjct: 338 SASC---GHGKT-TRQVLCMN--YQQPIDENYCDPEVRPLMEQECS-LAAC 381



 Score = 60.1 bits (139), Expect = 2e-08
 Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 8/108 (7%)

Query: 357 SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           S+  SEW+ C VTCG G  +R   C      V   S  +     + ++L   C    C  
Sbjct: 178 SWAASEWSECLVTCGKGTKQRQVWC---QLNVDHLSDGFCNSSTKPESL-SPCELHTCAS 233

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKP 464
           W VG W PC+  C   G ++   R V CV+++ + V++D+EC +  +P
Sbjct: 234 WQVGPWGPCTTTCG-HGYQM---RDVKCVNELASAVLEDTECHEASRP 277



 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 10/115 (8%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
           + +R   W  CS +C  G   R   C D++ +    S C     P     ++QC    C 
Sbjct: 424 NQWRTGPWGSCSSSCSGGLQHRAVVCQDENGQ--SASYCDAASKPPE---LQQCGPGPCP 478

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            W  G W  CS+ C   G  + K R V C      ++++D  C  V KP + I+C
Sbjct: 479 QWNYGNWGECSQTC---GGGI-KSRLVIC-QFPNGQILEDHNCEIVNKPPSVIQC 528



 Score = 48.0 bits (109), Expect = 7e-05
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 10/113 (8%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW 417
           +  SEW+ CS +CG G   R   C++     +  ++C  +     +   + C + +C  W
Sbjct: 124 WHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELS----RVTRENCNEFSCPSW 179

Query: 418 WVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
               W+ C   C     + TK+R V+C   V +  + D  C    KP +   C
Sbjct: 180 AASEWSECLVTC----GKGTKQRQVWCQLNVDH--LSDGFCNSSTKPESLSPC 226



 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 1/59 (1%)

Query: 352 LHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ-HQRVVEQSQCYHIEPPRHQALMKQC 409
           LH   S+++  W PC+ TCG GY  R  +C+++    V+E ++C+    P  +     C
Sbjct: 228 LHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQCSVSC 286



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 4/109 (3%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQR-VVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGA 421
           W  C+  C  G  RR   CI +    VV   +C H+  P    + + C     + W V  
Sbjct: 10  WEGCTKMCQ-GLQRRNITCIHKSDHSVVSDKECDHLPLPSF--VTQSCNTDCELRWHVIG 66

Query: 422 WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            + CS  C      +      Y + +     VDD  CG  +KP T   C
Sbjct: 67  KSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELC 115



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 16/57 (28%), Positives = 33/57 (57%), Gaps = 4/57 (7%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           ++  +W+PCS +CG G T R   C++ +Q+ ++++ C   +P     + ++C   AC
Sbjct: 329 WQAGDWSPCSASCGHGKTTRQVLCMN-YQQPIDENYC---DPEVRPLMEQECSLAAC 381



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 78  WSEWSECSRTCGAGVSTQSREC-NNPEPVNNGNYCIG-DRSRYKVCNTDPCP 127
           +SEWS+CSR+CG G  ++   C NN       N C    R   + CN   CP
Sbjct: 126 YSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSRVTRENCNEFSCP 177



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)

Query: 76  GPWS--EWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           G W   +WS CS +CG G +T+   C N +   + NYC
Sbjct: 327 GEWQAGDWSPCSASCGHGKTTRQVLCMNYQQPIDENYC 364



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
           P P P+   W  +  W ECS+TCG G+ ++   C  P
Sbjct: 474 PGPCPQ---WN-YGNWGECSQTCGGGIKSRLVICQFP 506



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 20/67 (29%), Positives = 26/67 (38%), Gaps = 4/67 (5%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRH--QALMKQCRKPACV 415
           +    W  CS TCG G   R   C   + +++E   C  +  P    Q  M  C  PA V
Sbjct: 480 WNYGNWGECSQTCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHAC--PADV 537

Query: 416 HWWVGAW 422
            W    W
Sbjct: 538 SWHQEPW 544



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 14/45 (31%), Positives = 23/45 (51%), Gaps = 5/45 (11%)

Query: 420 GAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKP 464
           G W  C+K+C     +  + R++ C+ K  + VV D EC  +  P
Sbjct: 8   GPWEGCTKMC-----QGLQRRNITCIHKSDHSVVSDKECDHLPLP 47



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 53  DMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECN-NPEPVNNGNYC 111
           D  CQ  + V R          W   SEWSEC  TCG G   +   C  N + +++G +C
Sbjct: 157 DNECQELSRVTRENCNEFSCPSWAA-SEWSECLVTCGKGTKQRQVWCQLNVDHLSDG-FC 214

Query: 112 IGDRSRYKVCNTDPCPIN 129
               S  K  +  PC ++
Sbjct: 215 ---NSSTKPESLSPCELH 229


>AB005297-1|BAA23647.1| 1584|Homo sapiens BAI 1 protein.
          Length = 1584

 Score = 61.3 bits (142), Expect = 7e-09
 Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 6/85 (7%)

Query: 43  PAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP 102
           P+  G  C    W + + C  +     P DG W  W+ W  CS TCGAG   + R C+  
Sbjct: 497 PSYGGAEC-QGHWVETRDCFLQQ---CPVDGKWQAWASWGSCSVTCGAGSQRRERVCSG- 551

Query: 103 EPVNNGNYCIGDRSRYKVCNTDPCP 127
            P   G  C G +  Y+ C T  CP
Sbjct: 552 -PFFGGAACQGPQDEYRQCGTQRCP 575



 Score = 57.2 bits (132), Expect = 1e-07
 Identities = 25/58 (43%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           P  G W  WS WS CS TCG G   ++R C  P+    GN C G   + K CN   CP
Sbjct: 407 PVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQ--FGGNPCEGPEKQTKFCNIALCP 462



 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 3/82 (3%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC-PINEP 131
           GGW  WS W EC+R CG G+ T++R C  P P   G  C G     + CN + C P    
Sbjct: 262 GGWKLWSLWGECTRDCGGGLQTRTRTC-LPAPGVEGGGCEGVLEEGRQCNREACGPAGRT 320

Query: 132 SFREVQCSRHNNMPYKNETIDE 153
           S R  Q  R  +   + E  DE
Sbjct: 321 SSRS-QSLRSTDARRREELGDE 341



 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 7/93 (7%)

Query: 39  TMMRPAAPGTTC-GPDMWCQNQTC-VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQS 96
           T   P   G  C GP+   Q + C +A  P  A  DG W  WS WS CS +C  G   ++
Sbjct: 435 TCRPPQFGGNPCEGPEK--QTKFCNIALCPGRAV-DGNWNEWSSWSACSASCSQGRQQRT 491

Query: 97  RECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           RECN P     G  C G     + C    CP++
Sbjct: 492 RECNGPS--YGGAECQGHWVETRDCFLQQCPVD 522



 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDP 125
           P+P   D     WS WS CS TCG G  T++R C +    +    C G     ++CN   
Sbjct: 348 PAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSS---SYSTQCSGPLREQRLCNNSA 404

Query: 126 -CPIN 129
            CP++
Sbjct: 405 VCPVH 409


>BC111720-1|AAI11721.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    ++ V    +  P  G W  WS WS CS TCG G  T++R C  P+   
Sbjct: 323 GTHCSGPL---RESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQ--Y 377

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G  + +K CN   CP++
Sbjct: 378 GGRPCEGPETHHKPCNIALCPVD 400



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W  WS WS+CS TC  G   +SR+C      + G+ C G  +  + C    C  N
Sbjct: 398 PVDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESRECYNPECTAN 455



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPIN 129
           + G   WS+WS CS TCG G   ++R C +P     G +C G     +VC NT  CP++
Sbjct: 291 ESGVEEWSQWSTCSVTCGQGSQVRTRTCVSP----YGTHCSGPLRESRVCNNTALCPVH 345



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 47  GTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           G+ C GP  W +++ C    P     +G W  W  WS CS++C  G   + R C     V
Sbjct: 434 GSECRGP--WAESRECY--NPE-CTANGQWNQWGHWSGCSKSCDGGWERRIRTCQG--AV 486

Query: 106 NNGNYCIGDRSRYKVCNTDPCP 127
             G  C G     + C+   CP
Sbjct: 487 ITGQQCEGTGEEVRRCSEQRCP 508



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSVTC  G  +R  +C          S+C        +    +C      + W G
Sbjct: 407 SSWSQCSVTCSNGTQQRSRQCT---AAAHGGSECRGPWAESRECYNPECTANGQWNQW-G 462

Query: 421 AWNPCSKLC 429
            W+ CSK C
Sbjct: 463 HWSGCSKSC 471


>AL391807-1|CAI21673.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    ++ V    +  P  G W  WS WS CS TCG G  T++R C  P+   
Sbjct: 323 GTHCSGPL---RESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQ--Y 377

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G  + +K CN   CP++
Sbjct: 378 GGRPCEGPETHHKPCNIALCPVD 400



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W  WS WS+CS TC  G   +SR+C      + G+ C G  +  + C    C  N
Sbjct: 398 PVDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESRECYNPECTAN 455



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPIN 129
           + G   WS+WS CS TCG G   ++R C +P     G +C G     +VC NT  CP++
Sbjct: 291 ESGVEEWSQWSTCSVTCGQGSQVRTRTCVSP----YGTHCSGPLRESRVCNNTALCPVH 345



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 47  GTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           G+ C GP  W +++ C    P     +G W  W  WS CS++C  G   + R C     V
Sbjct: 434 GSECRGP--WAESRECY--NPE-CTANGQWNQWGHWSGCSKSCDGGWERRIRTCQG--AV 486

Query: 106 NNGNYCIGDRSRYKVCNTDPCP 127
             G  C G     + CN   CP
Sbjct: 487 ITGQQCEGTGEEVRRCNEQRCP 508



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSVTC  G  +R  +C          S+C        +    +C      + W G
Sbjct: 407 SSWSQCSVTCSNGTQQRSRQCT---AAAHGGSECRGPWAESRECYNPECTANGQWNQW-G 462

Query: 421 AWNPCSKLC 429
            W+ CSK C
Sbjct: 463 HWSGCSKSC 471


>AL359714-1|CAH71522.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    ++ V    +  P  G W  WS WS CS TCG G  T++R C  P+   
Sbjct: 323 GTHCSGPL---RESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQ--Y 377

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G  + +K CN   CP++
Sbjct: 378 GGRPCEGPETHHKPCNIALCPVD 400



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W  WS WS+CS TC  G   +SR+C      + G+ C G  +  + C    C  N
Sbjct: 398 PVDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESRECYNPECTAN 455



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPIN 129
           + G   WS+WS CS TCG G   ++R C +P     G +C G     +VC NT  CP++
Sbjct: 291 ESGVEEWSQWSTCSVTCGQGSQVRTRTCVSP----YGTHCSGPLRESRVCNNTALCPVH 345



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 47  GTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           G+ C GP  W +++ C    P     +G W  W  WS CS++C  G   + R C     V
Sbjct: 434 GSECRGP--WAESRECY--NPE-CTANGQWNQWGHWSGCSKSCDGGWERRIRTCQG--AV 486

Query: 106 NNGNYCIGDRSRYKVCNTDPCP 127
             G  C G     + CN   CP
Sbjct: 487 ITGQQCEGTGEEVRRCNEQRCP 508



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSVTC  G  +R  +C          S+C        +    +C      + W G
Sbjct: 407 SSWSQCSVTCSNGTQQRSRQCT---AAAHGGSECRGPWAESRECYNPECTANGQWNQW-G 462

Query: 421 AWNPCSKLC 429
            W+ CSK C
Sbjct: 463 HWSGCSKSC 471


>AL356117-1|CAH71772.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    ++ V    +  P  G W  WS WS CS TCG G  T++R C  P+   
Sbjct: 323 GTHCSGPL---RESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQ--Y 377

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G  + +K CN   CP++
Sbjct: 378 GGRPCEGPETHHKPCNIALCPVD 400



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W  WS WS+CS TC  G   +SR+C      + G+ C G  +  + C    C  N
Sbjct: 398 PVDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESRECYNPECTAN 455



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPIN 129
           + G   WS+WS CS TCG G   ++R C +P     G +C G     +VC NT  CP++
Sbjct: 291 ESGVEEWSQWSTCSVTCGQGSQVRTRTCVSP----YGTHCSGPLRESRVCNNTALCPVH 345



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 47  GTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           G+ C GP  W +++ C    P     +G W  W  WS CS++C  G   + R C     V
Sbjct: 434 GSECRGP--WAESRECY--NPE-CTANGQWNQWGHWSGCSKSCDGGWERRIRTCQG--AV 486

Query: 106 NNGNYCIGDRSRYKVCNTDPCP 127
             G  C G     + CN   CP
Sbjct: 487 ITGQQCEGTGEEVRRCNEQRCP 508



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSVTC  G  +R  +C          S+C        +    +C      + W G
Sbjct: 407 SSWSQCSVTCSNGTQQRSRQCT---AAAHGGSECRGPWAESRECYNPECTANGQWNQW-G 462

Query: 421 AWNPCSKLC 429
            W+ CSK C
Sbjct: 463 HWSGCSKSC 471


>AL160401-1|CAH73864.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    ++ V    +  P  G W  WS WS CS TCG G  T++R C  P+   
Sbjct: 323 GTHCSGPL---RESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQ--Y 377

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G  + +K CN   CP++
Sbjct: 378 GGRPCEGPETHHKPCNIALCPVD 400



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W  WS WS+CS TC  G   +SR+C      + G+ C G  +  + C    C  N
Sbjct: 398 PVDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESRECYNPECTAN 455



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPIN 129
           + G   WS+WS CS TCG G   ++R C +P     G +C G     +VC NT  CP++
Sbjct: 291 ESGVEEWSQWSTCSVTCGQGSQVRTRTCVSP----YGTHCSGPLRESRVCNNTALCPVH 345



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 47  GTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           G+ C GP  W +++ C    P     +G W  W  WS CS++C  G   + R C     V
Sbjct: 434 GSECRGP--WAESRECY--NPE-CTANGQWNQWGHWSGCSKSCDGGWERRIRTCQG--AV 486

Query: 106 NNGNYCIGDRSRYKVCNTDPCP 127
             G  C G     + CN   CP
Sbjct: 487 ITGQQCEGTGEEVRRCNEQRCP 508



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSVTC  G  +R  +C          S+C        +    +C      + W G
Sbjct: 407 SSWSQCSVTCSNGTQQRSRQCT---AAAHGGSECRGPWAESRECYNPECTANGQWNQW-G 462

Query: 421 AWNPCSKLC 429
            W+ CSK C
Sbjct: 463 HWSGCSKSC 471


>AL158051-1|CAI19625.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    ++ V    +  P  G W  WS WS CS TCG G  T++R C  P+   
Sbjct: 323 GTHCSGPL---RESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQ--Y 377

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G  + +K CN   CP++
Sbjct: 378 GGRPCEGPETHHKPCNIALCPVD 400



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W  WS WS+CS TC  G   +SR+C      + G+ C G  +  + C    C  N
Sbjct: 398 PVDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESRECYNPECTAN 455



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPIN 129
           + G   WS+WS CS TCG G   ++R C +P     G +C G     +VC NT  CP++
Sbjct: 291 ESGVEEWSQWSTCSVTCGQGSQVRTRTCVSP----YGTHCSGPLRESRVCNNTALCPVH 345



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 47  GTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           G+ C GP  W +++ C    P     +G W  W  WS CS++C  G   + R C     V
Sbjct: 434 GSECRGP--WAESRECY--NPE-CTANGQWNQWGHWSGCSKSCDGGWERRIRTCQG--AV 486

Query: 106 NNGNYCIGDRSRYKVCNTDPCP 127
             G  C G     + CN   CP
Sbjct: 487 ITGQQCEGTGEEVRRCNEQRCP 508



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSVTC  G  +R  +C          S+C        +    +C      + W G
Sbjct: 407 SSWSQCSVTCSNGTQQRSRQCT---AAAHGGSECRGPWAESRECYNPECTANGQWNQW-G 462

Query: 421 AWNPCSKLC 429
            W+ CSK C
Sbjct: 463 HWSGCSKSC 471


>AL133378-1|CAC34969.2| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    ++ V    +  P  G W  WS WS CS TCG G  T++R C  P+   
Sbjct: 323 GTHCSGPL---RESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQ--Y 377

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G  + +K CN   CP++
Sbjct: 378 GGRPCEGPETHHKPCNIALCPVD 400



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W  WS WS+CS TC  G   +SR+C      + G+ C G  +  + C    C  N
Sbjct: 398 PVDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESRECYNPECTAN 455



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPIN 129
           + G   WS+WS CS TCG G   ++R C +P     G +C G     +VC NT  CP++
Sbjct: 291 ESGVEEWSQWSTCSVTCGQGSQVRTRTCVSP----YGTHCSGPLRESRVCNNTALCPVH 345



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 47  GTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           G+ C GP  W +++ C    P     +G W  W  WS CS++C  G   + R C     V
Sbjct: 434 GSECRGP--WAESRECY--NPE-CTANGQWNQWGHWSGCSKSCDGGWERRIRTCQG--AV 486

Query: 106 NNGNYCIGDRSRYKVCNTDPCP 127
             G  C G     + CN   CP
Sbjct: 487 ITGQQCEGTGEEVRRCNEQRCP 508



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSVTC  G  +R  +C          S+C        +    +C      + W G
Sbjct: 407 SSWSQCSVTCSNGTQQRSRQCT---AAAHGGSECRGPWAESRECYNPECTANGQWNQW-G 462

Query: 421 AWNPCSKLC 429
            W+ CSK C
Sbjct: 463 HWSGCSKSC 471


>AK023772-1|BAB14673.1|  538|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13710 fis, clone PLACE2000373, weakly similar to
           F-SPONDIN PRECURSOR. ).
          Length = 538

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 37/121 (30%), Positives = 54/121 (44%), Gaps = 13/121 (10%)

Query: 360 LSEWTPCSVTCGVGYTRRYYECIDQHQR---VVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           + EW+ CS TCG+G   R   C   +      V+  +C H+E P        C+   C  
Sbjct: 202 IGEWSECSKTCGLGMQHRQVLCRQVYANRSLTVQPYRCQHLEKPE---TTSTCQLKICSE 258

Query: 417 WWVGA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPA 475
           W +   W  CS  C + G+   + R V CV  +   VVDD EC   ++P   I+  D+  
Sbjct: 259 WQIRTDWTSCSVPCGV-GQ---RTRDVKCVSNI-GDVVDDEECNMKLRP-NDIENCDMGP 312

Query: 476 C 476
           C
Sbjct: 313 C 313



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 37/120 (30%), Positives = 53/120 (44%), Gaps = 14/120 (11%)

Query: 357 SYRLSEWTP-CSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC- 414
           S+ L+EW+   S  CG G   R   C+  H   +    C +  P    A    C    C 
Sbjct: 316 SWFLTEWSERSSAECGAGVRTRSVVCMTNHVSSLPLEGCGNNRP----AEATPCDNGPCT 371

Query: 415 --VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMN--KVVDDSECGQVIKPITTIKC 470
             V W+ G+W+ CS  C       T++R V CV K  +  +V+D SEC  + KP +   C
Sbjct: 372 GKVEWFAGSWSQCSIEC----GSGTQQREVICVRKNADTFEVLDPSECSFLEKPPSQQSC 427



 Score = 48.0 bits (109), Expect = 7e-05
 Identities = 35/125 (28%), Positives = 52/125 (41%), Gaps = 12/125 (9%)

Query: 351 RLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ--HQRVVEQSQCYHIEPPRHQALMKQ 408
           R  + H+++    T CS TCG G     + C+ +  H+   E S C     P  +   + 
Sbjct: 134 RRSRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRSTHEEAPE-SYCDSSMKPTPEE--EP 190

Query: 409 CRKPACVHWW-VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNK--VVDDSECGQVIKPI 465
           C    C  +W +G W+ CSK C +      + R V C     N+   V    C  + KP 
Sbjct: 191 CNIFPCPAFWDIGEWSECSKTCGLG----MQHRQVLCRQVYANRSLTVQPYRCQHLEKPE 246

Query: 466 TTIKC 470
           TT  C
Sbjct: 247 TTSTC 251



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 7/71 (9%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQ---RVVEQSQCYHIEPPRHQALMKQCR-KPACVHWW 418
           W+ CS+ CG G  +R   C+ ++     V++ S+C  +E P  Q   + C  KP    W+
Sbjct: 381 WSQCSIECGSGTQQREVICVRKNADTFEVLDPSECSFLEKPPSQ---QSCHLKPCGAKWF 437

Query: 419 VGAWNPCSKLC 429
              W+ CSK C
Sbjct: 438 STEWSMCSKSC 448



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 9/115 (7%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV-HWWV 419
           ++WT CSV CGVG   R  +C+     VV+  +C     P     ++ C    C   W++
Sbjct: 263 TDWTSCSVPCGVGQRTRDVKCVSNIGDVVDDEECNMKLRPND---IENCDMGPCAKSWFL 319

Query: 420 GAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
             W+  S      G    + RSV C+   ++ +  +  CG   +P     C + P
Sbjct: 320 TEWSERSSAECGAG---VRTRSVVCMTNHVSSLPLEG-CGN-NRPAEATPCDNGP 369



 Score = 31.5 bits (68), Expect = 6.7
 Identities = 11/20 (55%), Positives = 14/20 (70%)

Query: 80  EWSECSRTCGAGVSTQSREC 99
           EWSECS+TCG G+  +   C
Sbjct: 204 EWSECSKTCGLGMQHRQVLC 223


>AB011122-1|BAA25476.2| 1524|Homo sapiens KIAA0550 protein protein.
          Length = 1524

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    ++ V    +  P  G W  WS WS CS TCG G  T++R C  P+   
Sbjct: 325 GTHCSGPL---RESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQ--Y 379

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G  + +K CN   CP++
Sbjct: 380 GGRPCEGPETHHKPCNIALCPVD 402



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W  WS WS+CS TC  G   +SR+C      + G+ C G  +  + C    C  N
Sbjct: 400 PVDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESRECYNPECTAN 457



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPIN 129
           + G   WS+WS CS TCG G   ++R C +P     G +C G     +VC NT  CP++
Sbjct: 293 ESGVEEWSQWSTCSVTCGQGSQVRTRTCVSP----YGTHCSGPLRESRVCNNTALCPVH 347



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 47  GTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           G+ C GP  W +++ C    P     +G W  W  WS CS++C  G   + R C     V
Sbjct: 436 GSECRGP--WAESRECY--NPE-CTANGQWNQWGHWSGCSKSCDGGWERRIRTCQG--AV 488

Query: 106 NNGNYCIGDRSRYKVCNTDPCP 127
             G  C G     + C+   CP
Sbjct: 489 ITGQQCEGTGEEVRRCSEQRCP 510



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSVTC  G  +R  +C          S+C        +    +C      + W G
Sbjct: 409 SSWSQCSVTCSNGTQQRSRQCT---AAAHGGSECRGPWAESRECYNPECTANGQWNQW-G 464

Query: 421 AWNPCSKLC 429
            W+ CSK C
Sbjct: 465 HWSGCSKSC 473


>AB005299-1|BAA25363.1| 1522|Homo sapiens BAI 3 protein.
          Length = 1522

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    ++ V    +  P  G W  WS WS CS TCG G  T++R C  P+   
Sbjct: 323 GTHCSGPL---RESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQ--Y 377

Query: 107 NGNYCIGDRSRYKVCNTDPCPIN 129
            G  C G  + +K CN   CP++
Sbjct: 378 GGRPCEGPETHHKPCNIALCPVD 400



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           P DG W  WS WS+CS TC  G   +SR+C      + G+ C G  +  + C    C  N
Sbjct: 398 PVDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESRECYNPECTAN 455



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 5/59 (8%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-NTDPCPIN 129
           + G   WS+WS CS TCG G   ++R C +P     G +C G     +VC NT  CP++
Sbjct: 291 ESGVEEWSQWSTCSVTCGQGSQVRTRTCVSP----YGTHCSGPLRESRVCNNTALCPVH 345



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 47  GTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV 105
           G+ C GP  W +++ C    P     +G W  W  WS CS++C  G   + R C     V
Sbjct: 434 GSECRGP--WAESRECY--NPE-CTANGQWNQWGHWSGCSKSCDGGWERRIRTCQG--AV 486

Query: 106 NNGNYCIGDRSRYKVCNTDPCP 127
             G  C G     + C+   CP
Sbjct: 487 ITGQQCEGTGEEVRRCSEQRCP 508



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSVTC  G  +R  +C          S+C        +    +C      + W G
Sbjct: 407 SSWSQCSVTCSNGTQQRSRQCT---AAAHGGSECRGPWAESRECYNPECTANGQWNQW-G 462

Query: 421 AWNPCSKLC 429
            W+ CSK C
Sbjct: 463 HWSGCSKSC 471


>AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein.
          Length = 1322

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 6/97 (6%)

Query: 38  TTMMRPAAPGTTCGPDMWCQNQTCVART----PSPAPRD-GGWGPWSEWSECSRTCGAGV 92
           + M+ P+    T  P   C  Q    R     PSP  +  G WGPWS W  CSRTCG   
Sbjct: 663 SAMLPPSTRALTPLPPQVCDGQPDCGRPGQVGPSPEEQGCGAWGPWSPWGPCSRTCGPWG 722

Query: 93  STQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
             +SR C +P  +     C G   + + C T  CP++
Sbjct: 723 QGRSRRC-SPLGLLVLQNCPGPEHQSQACFTAACPVD 758



 Score = 55.6 bits (128), Expect = 4e-07
 Identities = 36/123 (29%), Positives = 49/123 (39%), Gaps = 11/123 (8%)

Query: 13  GAEAGLCSKLSELCEHLWCLVDNVCTTMMRPAA--PGTTCGPDMWCQNQTCVARTP---- 66
           G+    C +   L    WC+    C  ++  A   PG     D  CQ   C    P    
Sbjct: 852 GSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD--CQLCICQDGRPRRCR 909

Query: 67  -SP-APRDGGWGPWSEWSECSRTCGA-GVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNT 123
            +P    D GW  WS W++C   CG+  +    R  NNP P   G  C G   + + C T
Sbjct: 910 LNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQT 969

Query: 124 DPC 126
           +PC
Sbjct: 970 EPC 972



 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 7/72 (9%)

Query: 57  QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIG-DR 115
           Q+Q C     +  P DG W  WS WS CS  C  G  T+ R+C++P+  N G  C     
Sbjct: 746 QSQACFT---AACPVDGEWSTWSPWSVCSEPC-RGTMTRQRQCHSPQ--NGGRTCAALPG 799

Query: 116 SRYKVCNTDPCP 127
             +    T PCP
Sbjct: 800 GLHSTRQTKPCP 811


>X86328-1|CAA60121.1|  820|Homo sapiens complement C7 protein.
          Length = 820

 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 23/53 (43%), Positives = 29/53 (54%), Gaps = 4/53 (7%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD 124
           DGGW  WS WS C +    G  T+SRECNNP P   G  C+G+ +    C  +
Sbjct: 498 DGGWSCWSSWSPCVQ----GKKTRSRECNNPPPSGGGRSCVGETTESTQCEDE 546


>J03507-1|AAA51861.1|  843|Homo sapiens C7 protein.
          Length = 843

 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 23/53 (43%), Positives = 29/53 (54%), Gaps = 4/53 (7%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD 124
           DGGW  WS WS C +    G  T+SRECNNP P   G  C+G+ +    C  +
Sbjct: 500 DGGWSCWSSWSPCVQ----GKKTRSRECNNPPPSGGGRSCVGETTESTQCEDE 548


>BC094811-1|AAH94811.1|  602|Homo sapiens ADAMTSL4 protein protein.
          Length = 602

 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 8/130 (6%)

Query: 222 CGVCGGDGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKS 281
           CGVCGGD + C+ V G  T       G+ ++  IPAG+  ++I +     NY+++     
Sbjct: 2   CGVCGGDDSTCRLVSGNLT-DRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGG 60

Query: 282 RRMFLNGARNATLTEYFVAGAQAIYER----DRDWEKVRISGPLAEDIKVYQRIFRGRHR 337
           R +            Y   G    Y R    +   E +   GP  + + VY  IF  +  
Sbjct: 61  RSIINGNWAVDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYM-IF--QEE 117

Query: 338 NPGVTYQYTV 347
           NPGV YQY +
Sbjct: 118 NPGVFYQYVI 127



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQH---QRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           +   EWT CS +CG G   R  +C  +       V   +C H+  P    + + C+   C
Sbjct: 255 WEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLPRPN---ITQSCQLRLC 311

Query: 415 VHWWVGA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            HW VG+ W+ CS  C   G+   + R V CV    ++ V + EC
Sbjct: 312 GHWEVGSPWSQCSVRCGR-GQ---RSRQVRCVGNNGDE-VSEQEC 351



 Score = 48.4 bits (110), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 14/116 (12%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQ---HQRVVEQSQCYHIEPPRHQALMKQCRKPACV-HWW 418
           W  CS  CG G  RR   C+ +      V   S C H+  PR  AL + C+  AC   W+
Sbjct: 447 WGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHL--PRPPAL-QPCQGQACQDRWF 503

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
              W+PCS+ C    +  T+ R V C+    N+ +  + C   ++P     C   P
Sbjct: 504 STPWSPCSRSC----QGGTQTREVQCLS--TNQTL-STRCPPQLRPSRKRPCNSQP 552



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 12/110 (10%)

Query: 366 CSVTCGVGYTRRYYECIDQH--QRVVEQSQCYHIEPPRHQALMKQCRKPACVHWW-VGAW 422
           CS +CG G  R  + CI +   + + E+S      PP   A  + C    C  +W  G W
Sbjct: 204 CSASCGKGVWRPIFLCISRESGEELDERSCAAGARPP---ASPEPCHGTPCPPYWEAGEW 260

Query: 423 NPCSKLCHMPGEEVTKERSVYCVDKV--MNKVVDDSECGQVIKPITTIKC 470
             CS+ C  PG   T+ R + C  +       V    CG + +P  T  C
Sbjct: 261 TSCSRSCG-PG---TQHRQLQCRQEFGGGGSSVPPERCGHLPRPNITQSC 306



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSV CG G   R   C+  +   V + +C    PP+  +       P    W+  
Sbjct: 318 SPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECAS-GPPQPPSREACDMGPCTTAWFHS 376

Query: 421 AW-NPCSKLCHMPGEEVTKERSVYCV 445
            W + CS  C   G  + + RSV C+
Sbjct: 377 DWSSKCSAEC---GTGI-QRRSVVCL 398



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 20/124 (16%)

Query: 361 SEWTP-CSVTCGVGYTRRYYECIDQHQRV----------VEQSQCYHIEPPRHQAL-MKQ 408
           S+W+  CS  CG G  RR   C+     +            QS      PP  +A  +  
Sbjct: 376 SDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDMRACSLGP 435

Query: 409 CRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNK--VVDDSECGQVIKPIT 466
           C +     W+ G W  CS  C       T+ R + CV K+  +  V   S C  + +P  
Sbjct: 436 CERTW--RWYTGPWGECSSEC----GSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPPA 489

Query: 467 TIKC 470
              C
Sbjct: 490 LQPC 493



 Score = 33.1 bits (72), Expect = 2.2
 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSREC--NNPEPVNNGNYCIG--DRSRYKVCNTDPC 126
           G W   S WS+CS  CG G  ++   C  NN + V+      G       + C+  PC
Sbjct: 312 GHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREACDMGPC 369



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 81  WSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
           WS CSR+C  G  T+  +C +     +       R SR + CN+ PC
Sbjct: 507 WSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRKRPCNSQPC 553



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 63  ARTP-SPAPRDGGWGP--WS--EWSECSRTCGAGVSTQSREC 99
           AR P SP P  G   P  W   EW+ CSR+CG G   +  +C
Sbjct: 237 ARPPASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQC 278


>BC071852-1|AAH71852.1|  602|Homo sapiens ADAMTSL4 protein protein.
          Length = 602

 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 8/130 (6%)

Query: 222 CGVCGGDGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQEKVSPGNYISIGSTKS 281
           CGVCGGD + C+ V G  T       G+ ++  IPAG+  ++I +     NY+++     
Sbjct: 2   CGVCGGDDSTCRLVSGNLT-DRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGG 60

Query: 282 RRMFLNGARNATLTEYFVAGAQAIYER----DRDWEKVRISGPLAEDIKVYQRIFRGRHR 337
           R +            Y   G    Y R    +   E +   GP  + + VY  IF  +  
Sbjct: 61  RSIINGNWAVDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYM-IF--QEE 117

Query: 338 NPGVTYQYTV 347
           NPGV YQY +
Sbjct: 118 NPGVFYQYVI 127



 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQH---QRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           +   EWT CS +CG G   R  +C  +       V   +C H+  P    + + C+   C
Sbjct: 255 WEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLPRPN---ITQSCQLRLC 311

Query: 415 VHWWVGA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            HW VG+ W+ CS  C   G+   + R V CV    ++ V + EC
Sbjct: 312 GHWEVGSPWSQCSVRCGR-GQ---RSRQVRCVGNNGDE-VSEQEC 351



 Score = 48.4 bits (110), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 14/116 (12%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQ---HQRVVEQSQCYHIEPPRHQALMKQCRKPACV-HWW 418
           W  CS  CG G  RR   C+ +      V   S C H+  PR  AL + C+  AC   W+
Sbjct: 447 WGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHL--PRPPAL-QPCQGQACQDRWF 503

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
              W+PCS+ C    +  T+ R V C+    N+ +  + C   ++P     C   P
Sbjct: 504 STPWSPCSRSC----QGGTQTREVQCLS--TNQTL-STRCPPQLRPSRKRPCNSQP 552



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 12/110 (10%)

Query: 366 CSVTCGVGYTRRYYECIDQH--QRVVEQSQCYHIEPPRHQALMKQCRKPACVHWW-VGAW 422
           CS +CG G  R  + CI +   + + E+S      PP   A  + C    C  +W  G W
Sbjct: 204 CSASCGKGVWRPIFLCISRESGEELDERSCAAGARPP---ASPEPCHGTPCPPYWEAGEW 260

Query: 423 NPCSKLCHMPGEEVTKERSVYCVDKV--MNKVVDDSECGQVIKPITTIKC 470
             CS+ C  PG   T+ R + C  +       V    CG + +P  T  C
Sbjct: 261 TSCSRSCG-PG---TQHRQLQCRQEFGGGGSSVPPERCGHLPRPNITQSC 306



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSV CG G   R   C+  +   V + +C    PP+  +       P    W+  
Sbjct: 318 SPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECAS-GPPQPPSREACDMGPCTTAWFHS 376

Query: 421 AW-NPCSKLCHMPGEEVTKERSVYCV 445
            W + CS  C   G  + + RSV C+
Sbjct: 377 DWSSKCSAEC---GTGI-QRRSVVCL 398



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 20/124 (16%)

Query: 361 SEWTP-CSVTCGVGYTRRYYECIDQHQRV----------VEQSQCYHIEPPRHQAL-MKQ 408
           S+W+  CS  CG G  RR   C+     +            QS      PP  +A  +  
Sbjct: 376 SDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDMRACSLGP 435

Query: 409 CRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNK--VVDDSECGQVIKPIT 466
           C +     W+ G W  CS  C       T+ R + CV K+  +  V   S C  + +P  
Sbjct: 436 CERTW--RWYTGPWGECSSEC----GSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPPA 489

Query: 467 TIKC 470
              C
Sbjct: 490 LQPC 493



 Score = 33.1 bits (72), Expect = 2.2
 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSREC--NNPEPVNNGNYCIG--DRSRYKVCNTDPC 126
           G W   S WS+CS  CG G  ++   C  NN + V+      G       + C+  PC
Sbjct: 312 GHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREACDMGPC 369



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 81  WSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
           WS CSR+C  G  T+  +C +     +       R SR + CN+ PC
Sbjct: 507 WSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRKRPCNSQPC 553



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 63  ARTP-SPAPRDGGWGP--WS--EWSECSRTCGAGVSTQSREC 99
           AR P SP P  G   P  W   EW+ CSR+CG G   +  +C
Sbjct: 237 ARPPASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQC 278


>BC063851-1|AAH63851.1|  843|Homo sapiens complement component 7
           protein.
          Length = 843

 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 23/53 (43%), Positives = 29/53 (54%), Gaps = 4/53 (7%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD 124
           DGGW  WS WS C +    G  T+SRECNNP P   G  C+G+ +    C  +
Sbjct: 500 DGGWSCWSSWSPCVQ----GKKTRSRECNNPPPSGGGRSCVGETTESTQCEDE 548


>AK131380-1|BAD18531.1|  301|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16449 fis, clone BRAWH2006395, highly  similar
           to Rattus norvegicus transmembrane receptor Unc5H1. ).
          Length = 301

 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 25/61 (40%), Positives = 32/61 (52%), Gaps = 3/61 (4%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEP 131
           DG W PWS+WS C   C      +SREC++P P N G  C G     + C +D C  +E 
Sbjct: 242 DGSWSPWSKWSACGLDC---THWRSRECSDPAPRNGGEECQGTDLDTRNCTSDLCVHSES 298

Query: 132 S 132
           S
Sbjct: 299 S 299


>AY358143-1|AAQ88510.1|  219|Homo sapiens FVSY9334 protein.
          Length = 219

 Score = 56.4 bits (130), Expect = 2e-07
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 1/60 (1%)

Query: 207 VGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTRQSGFSEVAIIPAGSRNVKIQE 266
           +GCD  + SD   D CGVCGGD T C+ V G++    T   G+  V  IP G+  + I E
Sbjct: 26  IGCDDYLGSDKVVDKCGVCGGDNTGCQVVSGVFKHALT-SLGYHRVVEIPEGATKINITE 84


>X72177-1|CAA50994.1|  934|Homo sapiens complement component C6
           protein.
          Length = 934

 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 37/113 (32%), Positives = 50/113 (44%), Gaps = 18/113 (15%)

Query: 37  CTTMMRPAAPGTTCGPDMWCQNQT----CVARTPSPAPR--DGGWGPWSEWSECSRTCGA 90
           C    RP   GT C     CQ+ T    C  ++P       DG WG WS WS C  T   
Sbjct: 526 CPNNGRPTLSGTECL--CVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKR 583

Query: 91  GVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-------NTDPCPINEPSFREV 136
              +++RECNNP P   G  C G++ + + C       N  PC  ++   +EV
Sbjct: 584 ---SRTRECNNPAPQRGGKRCEGEKRQEEDCTFSIMENNGQPCINDDEEMKEV 633



 Score = 41.1 bits (92), Expect = 0.008
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 3/54 (5%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC--IGDRSRYKVCNTDPCPIN 129
           W++W+ CS+TC +G  ++ R+    +     N+C  I  +   + CN   CPIN
Sbjct: 29  WTQWTSCSKTCNSGTQSRHRQI-VVDKYYQENFCEQICSKQETRECNWQRCPIN 81


>J05064-1|AAA51860.1|  934|Homo sapiens C6 protein.
          Length = 934

 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 37/113 (32%), Positives = 50/113 (44%), Gaps = 18/113 (15%)

Query: 37  CTTMMRPAAPGTTCGPDMWCQNQT----CVARTPSPAPR--DGGWGPWSEWSECSRTCGA 90
           C    RP   GT C     CQ+ T    C  ++P       DG WG WS WS C  T   
Sbjct: 526 CPNNGRPTLSGTECL--CVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKR 583

Query: 91  GVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-------NTDPCPINEPSFREV 136
              +++RECNNP P   G  C G++ + + C       N  PC  ++   +EV
Sbjct: 584 ---SRTRECNNPAPQRGGKRCEGEKRQEEDCTFSIMENNGQPCINDDEEMKEV 633



 Score = 41.1 bits (92), Expect = 0.008
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 3/54 (5%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC--IGDRSRYKVCNTDPCPIN 129
           W++W+ CS+TC +G  ++ R+    +     N+C  I  +   + CN   CPIN
Sbjct: 29  WTQWTSCSKTCNSGTQSRHRQI-VVDKYYQENFCEQICSKQETRECNWQRCPIN 81


>J05024-1|AAA59668.1|  934|Homo sapiens completement component C6
           protein.
          Length = 934

 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 37/113 (32%), Positives = 50/113 (44%), Gaps = 18/113 (15%)

Query: 37  CTTMMRPAAPGTTCGPDMWCQNQT----CVARTPSPAPR--DGGWGPWSEWSECSRTCGA 90
           C    RP   GT C     CQ+ T    C  ++P       DG WG WS WS C  T   
Sbjct: 526 CPNNGRPTLSGTECL--CVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKR 583

Query: 91  GVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-------NTDPCPINEPSFREV 136
              +++RECNNP P   G  C G++ + + C       N  PC  ++   +EV
Sbjct: 584 ---SRTRECNNPAPQRGGKRCEGEKRQEEDCTFSIMENNGQPCINDDEEMKEV 633



 Score = 41.1 bits (92), Expect = 0.008
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 3/54 (5%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC--IGDRSRYKVCNTDPCPIN 129
           W++W+ CS+TC +G  ++ R+    +     N+C  I  +   + CN   CPIN
Sbjct: 29  WTQWTSCSKTCNSGTQSRHRQI-VVDKYYQENFCEQICSKQETRECNWQRCPIN 81


>BC035723-1|AAH35723.1|  934|Homo sapiens C6 protein protein.
          Length = 934

 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 37/113 (32%), Positives = 50/113 (44%), Gaps = 18/113 (15%)

Query: 37  CTTMMRPAAPGTTCGPDMWCQNQT----CVARTPSPAPR--DGGWGPWSEWSECSRTCGA 90
           C    RP   GT C     CQ+ T    C  ++P       DG WG WS WS C  T   
Sbjct: 526 CPNNGRPTLSGTECL--CVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKR 583

Query: 91  GVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-------NTDPCPINEPSFREV 136
              +++RECNNP P   G  C G++ + + C       N  PC  ++   +EV
Sbjct: 584 ---SRTRECNNPAPQRGGKRCEGEKRQEEDCTFSIMENNGQPCINDDEEMKEV 633



 Score = 41.1 bits (92), Expect = 0.008
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 3/54 (5%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC--IGDRSRYKVCNTDPCPIN 129
           W++W+ CS+TC +G  ++ R+    +     N+C  I  +   + CN   CPIN
Sbjct: 29  WTQWTSCSKTCNSGTQSRHRQI-VVDKYYQENFCEQICSKQETRECNWQRCPIN 81


>AB126592-1|BAD02321.1|  934|Homo sapiens complement component 6
           protein.
          Length = 934

 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 37/113 (32%), Positives = 50/113 (44%), Gaps = 18/113 (15%)

Query: 37  CTTMMRPAAPGTTCGPDMWCQNQT----CVARTPSPAPR--DGGWGPWSEWSECSRTCGA 90
           C    RP   GT C     CQ+ T    C  ++P       DG WG WS WS C  T   
Sbjct: 526 CPNNGRPTLSGTECL--CVCQSGTYGENCEKQSPDYKSNAVDGHWGCWSSWSTCDATYKR 583

Query: 91  GVSTQSRECNNPEPVNNGNYCIGDRSRYKVC-------NTDPCPINEPSFREV 136
              +++RECNNP P   G  C G++ + + C       N  PC  ++   +EV
Sbjct: 584 ---SRTRECNNPAPQRGGKRCEGEKRQEEDCTFSIIENNGQPCINDDEEMKEV 633



 Score = 41.1 bits (92), Expect = 0.008
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 3/54 (5%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC--IGDRSRYKVCNTDPCPIN 129
           W++W+ CS+TC +G  ++ R+    +     N+C  I  +   + CN   CPIN
Sbjct: 29  WTQWTSCSKTCNSGTQSRHRQI-VVDKYYQENFCEQICSKQETRECNWQRCPIN 81


>BC033727-1|AAH33727.1|  364|Homo sapiens Unknown (protein for
           IMAGE:5166762) protein.
          Length = 364

 Score = 55.2 bits (127), Expect = 5e-07
 Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 3/55 (5%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           DG W PWS+WS C   C      +SREC++P P N G  C G     + C +D C
Sbjct: 202 DGSWSPWSKWSACGLDC---THWRSRECSDPAPRNGGEECQGTDLDTRNCTSDLC 253


>AL354919-5|CAI16890.1| 1584|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 1584

 Score = 54.8 bits (126), Expect = 6e-07
 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    +T      +  P  G W  W  WS CSR+CG G  ++ R C  P+  +
Sbjct: 342 GTLCSGPL---RETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQ--H 396

Query: 107 NGNYCIGDRSRYKVCNTDPCPI 128
            G  C G   + K+C+   CP+
Sbjct: 397 GGKACEGPELQTKLCSMAACPV 418



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 2/56 (3%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           D  WGPW+ WS CS+TC  G   + R C        G  C G     K C+   CP
Sbjct: 475 DSKWGPWNAWSLCSKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCP 528



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 8/93 (8%)

Query: 39  TMMRPAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSR 97
           T + P   G  C GP++  Q + C   + +  P +G W  W  W  CS +C  G   +SR
Sbjct: 390 TCVPPQHGGKACEGPEL--QTKLC---SMAACPVEGQWLEWGPWGPCSTSCANGTQQRSR 444

Query: 98  ECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           +C+   P      C G  +  + C+   CP  +
Sbjct: 445 KCSVAGPA--WATCTGALTDTRECSNLECPATD 475



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 9/69 (13%)

Query: 62  VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
           +A+T  PA  +     WS WS CS TCG G+  ++R C +  P   G  C G     + C
Sbjct: 304 MAQTGDPAAEE-----WSPWSVCSLTCGQGLQVRTRSCVS-SPY--GTLCSGPLRETRPC 355

Query: 122 NTD-PCPIN 129
           N    CP++
Sbjct: 356 NNSATCPVH 364



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/69 (27%), Positives = 27/69 (39%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CS+TCG G   R   C+      +         P  + A    C        W G
Sbjct: 316 SPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSA---TCPVHGVWEEW-G 371

Query: 421 AWNPCSKLC 429
           +W+ CS+ C
Sbjct: 372 SWSLCSRSC 380



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 18/115 (15%)

Query: 363 WTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV---HW- 417
           W+ CS +CG G   R   C+  QH        C   E P  Q   K C   AC     W 
Sbjct: 373 WSLCSRSCGRGSRSRMRTCVPPQH----GGKAC---EGPELQT--KLCSMAACPVEGQWL 423

Query: 418 -WVGAWNPCSKLCHMPGEEVTKERSVY--CVDKVMNKVVDDSECGQVIKPITTIK 469
            W G W PCS  C    ++ +++ SV           + D  EC  +  P T  K
Sbjct: 424 EW-GPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSK 477


>AL354919-2|CAM12875.1| 1554|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 1554

 Score = 54.8 bits (126), Expect = 6e-07
 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    +T      +  P  G W  W  WS CSR+CG G  ++ R C  P+  +
Sbjct: 330 GTLCSGPL---RETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQ--H 384

Query: 107 NGNYCIGDRSRYKVCNTDPCPI 128
            G  C G   + K+C+   CP+
Sbjct: 385 GGKACEGPELQTKLCSMAACPV 406



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 2/56 (3%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           D  WGPW+ WS CS+TC  G   + R C        G  C G     K C+   CP
Sbjct: 463 DSKWGPWNAWSLCSKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCP 516



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 8/93 (8%)

Query: 39  TMMRPAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSR 97
           T + P   G  C GP++  Q + C   + +  P +G W  W  W  CS +C  G   +SR
Sbjct: 378 TCVPPQHGGKACEGPEL--QTKLC---SMAACPVEGQWLEWGPWGPCSTSCANGTQQRSR 432

Query: 98  ECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           +C+   P      C G  +  + C+   CP  +
Sbjct: 433 KCSVAGPA--WATCTGALTDTRECSNLECPATD 463



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 9/69 (13%)

Query: 62  VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
           +A+T  PA  +     WS WS CS TCG G+  ++R C +  P   G  C G     + C
Sbjct: 292 MAQTGDPAAEE-----WSPWSVCSLTCGQGLQVRTRSCVS-SPY--GTLCSGPLRETRPC 343

Query: 122 NTD-PCPIN 129
           N    CP++
Sbjct: 344 NNSATCPVH 352



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/69 (27%), Positives = 27/69 (39%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CS+TCG G   R   C+      +         P  + A    C        W G
Sbjct: 304 SPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSA---TCPVHGVWEEW-G 359

Query: 421 AWNPCSKLC 429
           +W+ CS+ C
Sbjct: 360 SWSLCSRSC 368



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 18/115 (15%)

Query: 363 WTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV---HW- 417
           W+ CS +CG G   R   C+  QH        C   E P  Q   K C   AC     W 
Sbjct: 361 WSLCSRSCGRGSRSRMRTCVPPQH----GGKAC---EGPELQT--KLCSMAACPVEGQWL 411

Query: 418 -WVGAWNPCSKLCHMPGEEVTKERSVY--CVDKVMNKVVDDSECGQVIKPITTIK 469
            W G W PCS  C    ++ +++ SV           + D  EC  +  P T  K
Sbjct: 412 EW-GPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSK 465


>AB065648-1|BAC05874.1| 1573|Homo sapiens seven transmembrane helix
           receptor protein.
          Length = 1573

 Score = 54.8 bits (126), Expect = 6e-07
 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    +T      +  P  G W  W  WS CSR+CG G  ++ R C  P+  +
Sbjct: 330 GTLCSGPL---RETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQ--H 384

Query: 107 NGNYCIGDRSRYKVCNTDPCPI 128
            G  C G   + K+C+   CP+
Sbjct: 385 GGKACEGPELQTKLCSMAACPV 406



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 2/56 (3%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           D  WGPW+ WS CS+TC  G   + R C        G  C G     K C+   CP
Sbjct: 463 DSKWGPWNAWSLCSKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCP 516



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 8/93 (8%)

Query: 39  TMMRPAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSR 97
           T + P   G  C GP++  Q + C   + +  P +G W  W  W  CS +C  G   +SR
Sbjct: 378 TCVPPQHGGKACEGPEL--QTKLC---SMAACPVEGQWLEWGPWGPCSTSCANGTQQRSR 432

Query: 98  ECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           +C+   P      C G  +  + C+   CP  +
Sbjct: 433 KCSVAGPA--WATCTGALTDTRECSNLECPATD 463



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 9/69 (13%)

Query: 62  VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
           +A+T  PA  +     WS WS CS TCG G+  ++R C +  P   G  C G     + C
Sbjct: 292 MAQTGDPAAEE-----WSPWSVCSLTCGQGLQVRTRSCVS-SPY--GTLCSGPLRETRPC 343

Query: 122 NTD-PCPIN 129
           N    CP++
Sbjct: 344 NNSATCPVH 352



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/69 (27%), Positives = 27/69 (39%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CS+TCG G   R   C+      +         P  + A    C        W G
Sbjct: 304 SPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSA---TCPVHGVWEEW-G 359

Query: 421 AWNPCSKLC 429
           +W+ CS+ C
Sbjct: 360 SWSLCSRSC 368



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 18/115 (15%)

Query: 363 WTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV---HW- 417
           W+ CS +CG G   R   C+  QH        C   E P  Q   K C   AC     W 
Sbjct: 361 WSLCSRSCGRGSRSRMRTCVPPQH----GGKAC---EGPELQT--KLCSMAACPVEGQWL 411

Query: 418 -WVGAWNPCSKLCHMPGEEVTKERSVY--CVDKVMNKVVDDSECGQVIKPITTIK 469
            W G W PCS  C    ++ +++ SV           + D  EC  +  P T  K
Sbjct: 412 EW-GPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSK 465


>AB005298-1|BAA25362.1| 1572|Homo sapiens BAI 2 protein.
          Length = 1572

 Score = 54.8 bits (126), Expect = 6e-07
 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    +T      +  P  G W  W  WS CSR+CG G  ++ R C  P+  +
Sbjct: 330 GTLCSGPL---RETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQ--H 384

Query: 107 NGNYCIGDRSRYKVCNTDPCPI 128
            G  C G   + K+C+   CP+
Sbjct: 385 GGKACEGPELQTKLCSMAACPV 406



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 2/56 (3%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           D  WGPW+ WS CS+TC  G   + R C        G  C G     K C+   CP
Sbjct: 463 DSKWGPWNAWSLCSKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCP 516



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 8/93 (8%)

Query: 39  TMMRPAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSR 97
           T + P   G  C GP++  Q + C   + +  P +G W  W  W  CS +C  G   +SR
Sbjct: 378 TCVPPQHGGKACEGPEL--QTKLC---SMAACPVEGQWLEWGPWGPCSTSCANGTQQRSR 432

Query: 98  ECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           +C+   P      C G  +  + C+   CP  +
Sbjct: 433 KCSVAGPA--WATCTGALTDTRECSNLECPATD 463



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 9/69 (13%)

Query: 62  VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
           +A+T  PA  +     WS WS CS TCG G+  ++R C +  P   G  C G     + C
Sbjct: 292 MAQTGDPAAEE-----WSPWSVCSLTCGQGLQVRTRSCVS-SPY--GTLCSGPLRETRPC 343

Query: 122 NTD-PCPIN 129
           N    CP++
Sbjct: 344 NNSATCPVH 352



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/69 (27%), Positives = 27/69 (39%), Gaps = 4/69 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CS+TCG G   R   C+      +         P  + A    C        W G
Sbjct: 304 SPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSA---TCPVHGVWEEW-G 359

Query: 421 AWNPCSKLC 429
           +W+ CS+ C
Sbjct: 360 SWSLCSRSC 368



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 18/115 (15%)

Query: 363 WTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV---HW- 417
           W+ CS +CG G   R   C+  QH        C   E P  Q   K C   AC     W 
Sbjct: 361 WSLCSRSCGRGSRSRMRTCVPPQH----GGKAC---EGPELQT--KLCSMAACPVEGQWL 411

Query: 418 -WVGAWNPCSKLCHMPGEEVTKERSVY--CVDKVMNKVVDDSECGQVIKPITTIK 469
            W G W PCS  C    ++ +++ SV           + D  EC  +  P T  K
Sbjct: 412 EW-GPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSK 465


>U08006-1|AAA82124.1|  584|Homo sapiens complement 8 alpha subunit
           protein.
          Length = 584

 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 43  PAAPGTTCGPD--MWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECN 100
           P   GT+C     +      C       A  DG W  WS WS     C AG+  + REC+
Sbjct: 508 PILEGTSCRCQCRLGSLGAACEQTQTEGAKADGSWSCWSSWS----VCRAGIQERRRECD 563

Query: 101 NPEPVNNGNYCIGDRSRYKVC 121
           NP P N G  C G + + + C
Sbjct: 564 NPAPQNGGASCSGRKVQTQAC 584


>M16974-1|AAA52200.1|  584|Homo sapiens C8A protein.
          Length = 584

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 43  PAAPGTTCGPD--MWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECN 100
           P   GT+C     +      C       A  DG W  WS WS     C AG+  + REC+
Sbjct: 508 PILEGTSCRCQCRLGSLGAACEQTQTEGAKADGSWSCWSSWS----VCRAGIQERRRECD 563

Query: 101 NPEPVNNGNYCIGDRSRYKVC 121
           NP P N G  C G + + + C
Sbjct: 564 NPAPQNGGASCPGRKVQTQAC 584


>BC132913-1|AAI32914.1|  584|Homo sapiens complement component 8,
           alpha polypeptide protein.
          Length = 584

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 43  PAAPGTTCGPD--MWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECN 100
           P   GT+C     +      C       A  DG W  WS WS     C AG+  + REC+
Sbjct: 508 PILEGTSCRCQCRLGSLGAACEQTQTEGAKADGSWSCWSSWS----VCRAGIQERRRECD 563

Query: 101 NPEPVNNGNYCIGDRSRYKVC 121
           NP P N G  C G + + + C
Sbjct: 564 NPAPQNGGASCPGRKVQTQAC 584


>BC132911-1|AAI32912.1|  584|Homo sapiens complement component 8,
           alpha polypeptide protein.
          Length = 584

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 43  PAAPGTTCGPD--MWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECN 100
           P   GT+C     +      C       A  DG W  WS WS     C AG+  + REC+
Sbjct: 508 PILEGTSCRCQCRLGSLGAACEQTQTEGAKADGSWSCWSSWS----VCRAGIQERRRECD 563

Query: 101 NPEPVNNGNYCIGDRSRYKVC 121
           NP P N G  C G + + + C
Sbjct: 564 NPAPQNGGASCPGRKVQTQAC 584


>AL121998-2|CAI19172.1|  584|Homo sapiens complement component 8,
           alpha polypeptide protein.
          Length = 584

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 43  PAAPGTTCGPD--MWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECN 100
           P   GT+C     +      C       A  DG W  WS WS     C AG+  + REC+
Sbjct: 508 PILEGTSCRCQCRLGSLGAACEQTQTEGAKADGSWSCWSSWS----VCRAGIQERRRECD 563

Query: 101 NPEPVNNGNYCIGDRSRYKVC 121
           NP P N G  C G + + + C
Sbjct: 564 NPAPQNGGASCPGRKVQTQAC 584


>DQ266047-1|ABB70405.1|  570|Homo sapiens ADAMTS16s alternative
           splice form protein.
          Length = 570

 Score = 52.8 bits (121), Expect = 3e-06
 Identities = 25/57 (43%), Positives = 33/57 (57%), Gaps = 3/57 (5%)

Query: 1   MFDAASQCHLQFGAEAGLCSK--LSELCEHLWC-LVDNVCTTMMRPAAPGTTCGPDM 54
           ++DA +QC  QFG +A LC      ++C+ LWC  +   C T   PAA GT CG DM
Sbjct: 511 LYDANTQCKWQFGEKAKLCMLDFKKDICKALWCHRIGRKCETKFMPAAEGTICGHDM 567


>X04393-1|CAA27981.1|  545|Homo sapiens complement C8-beta propetide
           /map='1p36.2- p22.1'on) protein.
          Length = 545

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 30/84 (35%), Positives = 35/84 (41%), Gaps = 10/84 (11%)

Query: 43  PAAPGTTCGPDMWC----QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRE 98
           P   G+ C  D  C    Q   C        P DG W  WS WS CS        T+ R+
Sbjct: 468 PVLKGSRC--DCICPVGSQGLACEVSYRKNTPIDGKWNCWSNWSSCS----GRRKTRQRQ 521

Query: 99  CNNPEPVNNGNYCIGDRSRYKVCN 122
           CNNP P N G+ C G  S    C+
Sbjct: 522 CNNPPPQNGGSPCSGPASETLDCS 545


>M16973-1|AAA51862.1|  591|Homo sapiens C8B protein.
          Length = 591

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 30/84 (35%), Positives = 35/84 (41%), Gaps = 10/84 (11%)

Query: 43  PAAPGTTCGPDMWC----QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRE 98
           P   G+ C  D  C    Q   C        P DG W  WS WS CS        T+ R+
Sbjct: 514 PVLKGSRC--DCICPVGSQGLACEVSYRKNTPIDGKWNCWSNWSSCS----GRRKTRQRQ 567

Query: 99  CNNPEPVNNGNYCIGDRSRYKVCN 122
           CNNP P N G+ C G  S    C+
Sbjct: 568 CNNPPPQNGGSPCSGPASETLDCS 591


>BC130575-1|AAI30576.1|  591|Homo sapiens complement component 8,
           beta polypeptide protein.
          Length = 591

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 30/84 (35%), Positives = 35/84 (41%), Gaps = 10/84 (11%)

Query: 43  PAAPGTTCGPDMWC----QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRE 98
           P   G+ C  D  C    Q   C        P DG W  WS WS CS        T+ R+
Sbjct: 514 PVLKGSRC--DCICPVGSQGLACEVSYRKNTPIDGKWNCWSNWSSCS----GRRKTRQRQ 567

Query: 99  CNNPEPVNNGNYCIGDRSRYKVCN 122
           CNNP P N G+ C G  S    C+
Sbjct: 568 CNNPPPQNGGSPCSGPASETLDCS 591


>AL121998-1|CAC18532.1|  591|Homo sapiens complement component 8,
           beta polypeptide protein.
          Length = 591

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 30/84 (35%), Positives = 35/84 (41%), Gaps = 10/84 (11%)

Query: 43  PAAPGTTCGPDMWC----QNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRE 98
           P   G+ C  D  C    Q   C        P DG W  WS WS CS        T+ R+
Sbjct: 514 PVLKGSRC--DCICPVGSQGLACEVSYRKNTPIDGKWNCWSNWSSCS----GRRKTRQRQ 567

Query: 99  CNNPEPVNNGNYCIGDRSRYKVCN 122
           CNNP P N G+ C G  S    C+
Sbjct: 568 CNNPPPQNGGSPCSGPASETLDCS 591


>AL354919-7|CAM12879.1| 1500|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 1500

 Score = 52.0 bits (119), Expect = 4e-06
 Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPI 128
           G W  W  WS CSR+CG G  ++ R C  P+  + G  C G   + K+C+   CP+
Sbjct: 313 GVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQ--HGGKACEGPELQTKLCSMAACPV 366



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 2/56 (3%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           D  WGPW+ WS CS+TC  G   + R C        G  C G     K C+   CP
Sbjct: 423 DSKWGPWNAWSLCSKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCP 476



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 8/93 (8%)

Query: 39  TMMRPAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSR 97
           T + P   G  C GP++  Q + C   + +  P +G W  W  W  CS +C  G   +SR
Sbjct: 338 TCVPPQHGGKACEGPEL--QTKLC---SMAACPVEGQWLEWGPWGPCSTSCANGTQQRSR 392

Query: 98  ECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           +C+   P      C G  +  + C+   CP  +
Sbjct: 393 KCSVAGPA--WATCTGALTDTRECSNLECPATD 423



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 18/115 (15%)

Query: 363 WTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV---HW- 417
           W+ CS +CG G   R   C+  QH        C   E P  Q   K C   AC     W 
Sbjct: 321 WSLCSRSCGRGSRSRMRTCVPPQH----GGKAC---EGPELQT--KLCSMAACPVEGQWL 371

Query: 418 -WVGAWNPCSKLCHMPGEEVTKERSVY--CVDKVMNKVVDDSECGQVIKPITTIK 469
            W G W PCS  C    ++ +++ SV           + D  EC  +  P T  K
Sbjct: 372 EW-GPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSK 425


>AL354919-3|CAM12876.1| 1499|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 1499

 Score = 52.0 bits (119), Expect = 4e-06
 Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPI 128
           G W  W  WS CSR+CG G  ++ R C  P+  + G  C G   + K+C+   CP+
Sbjct: 298 GVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQ--HGGKACEGPELQTKLCSMAACPV 351



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 2/56 (3%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           D  WGPW+ WS CS+TC  G   + R C        G  C G     K C+   CP
Sbjct: 408 DSKWGPWNAWSLCSKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCP 461



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 8/93 (8%)

Query: 39  TMMRPAAPGTTC-GPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSR 97
           T + P   G  C GP++  Q + C   + +  P +G W  W  W  CS +C  G   +SR
Sbjct: 323 TCVPPQHGGKACEGPEL--QTKLC---SMAACPVEGQWLEWGPWGPCSTSCANGTQQRSR 377

Query: 98  ECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           +C+   P      C G  +  + C+   CP  +
Sbjct: 378 KCSVAGPA--WATCTGALTDTRECSNLECPATD 408



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 18/115 (15%)

Query: 363 WTPCSVTCGVGYTRRYYECI-DQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV---HW- 417
           W+ CS +CG G   R   C+  QH        C   E P  Q   K C   AC     W 
Sbjct: 306 WSLCSRSCGRGSRSRMRTCVPPQH----GGKAC---EGPELQT--KLCSMAACPVEGQWL 356

Query: 418 -WVGAWNPCSKLCHMPGEEVTKERSVY--CVDKVMNKVVDDSECGQVIKPITTIK 469
            W G W PCS  C    ++ +++ SV           + D  EC  +  P T  K
Sbjct: 357 EW-GPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSK 410


>AY172951-1|AAO45695.1|  387|Homo sapiens disintegrin and
           metalloprotease-like protein protein.
          Length = 387

 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 9/112 (8%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQ--ALMKQCRKPACV 415
           + L  W+ CS TCG G  +R   C       + +SQC  +  P  Q   ++ +C K + +
Sbjct: 161 WSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQCTSLPRPELQEGCVLGRCPKNSRL 220

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDK-VMNKVV--DDSECGQVIKP 464
            W   +W+ CS  C +      ++R + C +K    K++   +  C  + KP
Sbjct: 221 QWVASSWSECSATCGLG----VRKREMKCSEKGFQGKLITFPERRCRNIKKP 268



 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 40/136 (29%), Positives = 62/136 (45%), Gaps = 16/136 (11%)

Query: 319 GPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQR-----LHKKHSYRLS-EWTPCSVTCGV 372
           GP  E + V++ + +G+  NPG+ ++Y + K         K+ +Y  S   + CSV+CG 
Sbjct: 1   GPTNETL-VFEILMQGK--NPGIAWKYALPKVMNGTPPATKRPAYTWSIVQSECSVSCGG 57

Query: 373 GYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVGAWNPCSKLCHM 431
           GY      C+      V  S C     P  +   K C   +C  +W  G W+ CSK C  
Sbjct: 58  GYINVKAICLRDQNTQVNSSFCSAKTKPVTEP--KICNAFSCPAYWMPGEWSTCSKAC-A 114

Query: 432 PGEEVTKERSVYCVDK 447
            G++    R + CV K
Sbjct: 115 GGQQ---SRKIQCVQK 127



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 6/104 (5%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVG 420
           EW+ CS  C  G   R  +C+ +     E++  + + P      ++ C   AC   W +G
Sbjct: 105 EWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPPQWSLG 164

Query: 421 AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKP 464
            W+ CSK C   G  V K R + C      + + +S+C  + +P
Sbjct: 165 PWSQCSKTC---GRGVRK-RELLCKGSAA-ETLPESQCTSLPRP 203



 Score = 34.3 bits (75), Expect = 0.95
 Identities = 16/50 (32%), Positives = 23/50 (46%)

Query: 81  WSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           W +C+ TCG GV T+S  C      ++           + CNT+ CP  E
Sbjct: 298 WQQCTVTCGGGVQTRSVHCVQQGRPSSTCLLHQKPPVLRACNTNFCPAPE 347



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNN-----GNYC-IGDRSRYKVCNTDPCPI 128
           W P  EWS CS+ C  G  ++  +C   +P         + C +   ++ + CN+  CP 
Sbjct: 101 WMP-GEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPP 159

Query: 129 NEPSFREVQCSR 140
                   QCS+
Sbjct: 160 QWSLGPWSQCSK 171



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 12/22 (54%), Positives = 15/22 (68%)

Query: 79  SEWSECSRTCGAGVSTQSRECN 100
           S WSECS TCG GV  +  +C+
Sbjct: 225 SSWSECSATCGLGVRKREMKCS 246


>AK122677-1|BAC85503.1|  375|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16125 fis, clone BRACE2027018. ).
          Length = 375

 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 9/112 (8%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQ--ALMKQCRKPACV 415
           + L  W+ CS TCG G  +R   C       + +SQC  +  P  Q   ++ +C K + +
Sbjct: 149 WSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQCTSLPRPELQEGCVLGRCPKNSRL 208

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDK-VMNKVV--DDSECGQVIKP 464
            W   +W+ CS  C +      ++R + C +K    K++   +  C  + KP
Sbjct: 209 QWVASSWSECSATCGLG----VRKREMKCREKGFQGKLITFPERRCRNIKKP 256



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 6/104 (5%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVG 420
           EW+ CS  C  G   R  +C+ +     E++  + + P      ++ C   AC   W +G
Sbjct: 93  EWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPPQWSLG 152

Query: 421 AWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKP 464
            W+ CSK C   G  V K R + C      + + +S+C  + +P
Sbjct: 153 PWSQCSKTC---GRGVRK-RELLCKGSAA-ETLPESQCTSLPRP 191



 Score = 48.0 bits (109), Expect = 7e-05
 Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 13/118 (11%)

Query: 337 RNPGVTYQYTVDKQR-----LHKKHSYRLS-EWTPCSVTCGVGYTRRYYECIDQHQRVVE 390
           +NPG+ ++Y + K         K+ +Y  S   + CSV+CG GY      C+      V 
Sbjct: 4   KNPGIAWKYALPKVMNGTPPATKRPAYTWSIVQSECSVSCGGGYINVKAICLRDQNTQVN 63

Query: 391 QSQCYHIEPPRHQALMKQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDK 447
            S C     P  +   K C   +C  +W  G W+ CSK C   G++    R + CV K
Sbjct: 64  SSFCSAKTKPVTEP--KICNAFSCPAYWMPGEWSTCSKAC-AGGQQ---SRKIQCVQK 115



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 16/50 (32%), Positives = 23/50 (46%)

Query: 81  WSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINE 130
           W +C+ TCG GV T+S  C      ++           + CNT+ CP  E
Sbjct: 286 WQQCTVTCGGGVQTRSVHCVQQGRPSSSCLLHQKPPVLRACNTNFCPAPE 335



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNN-----GNYC-IGDRSRYKVCNTDPCPI 128
           W P  EWS CS+ C  G  ++  +C   +P         + C +   ++ + CN+  CP 
Sbjct: 89  WMP-GEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPP 147

Query: 129 NEPSFREVQCSR 140
                   QCS+
Sbjct: 148 QWSLGPWSQCSK 159



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 12/21 (57%), Positives = 14/21 (66%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S WSECS TCG GV  +  +C
Sbjct: 213 SSWSECSATCGLGVRKREMKC 233


>AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open reading
           frame 9 protein.
          Length = 1263

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 14/140 (10%)

Query: 338 NPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRV-VEQSQCYH 396
           NP  T       Q   + + +    +T CS +CG G       C+++  R   E++ C  
Sbjct: 92  NPDETDGLFGGLQDFDELYDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLC-- 149

Query: 397 IEPPRHQALMKQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYC---VDKVMNK- 451
           +   R   L+K C    C   W +G W+PCS  C +      + R V+C   + + MN+ 
Sbjct: 150 VTSRRPPQLLKSCNLDPCPARWEIGKWSPCSLTCGVG----LQTRDVFCSHLLSREMNET 205

Query: 452 -VVDDSECGQVIKPITTIKC 470
            ++ D  C Q  KP T   C
Sbjct: 206 VILADELCRQP-KPSTVQAC 224



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 7/94 (7%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRH--QALMKQCRKPAC- 414
           + + +W+PCS+TCGVG   R   C     R + ++     E  R    + ++ C +  C 
Sbjct: 171 WEIGKWSPCSLTCGVGLQTRDVFCSHLLSREMNETVILADELCRQPKPSTVQACNRFNCP 230

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKV 448
             W+   W PCS+ C   G  V K R V C  ++
Sbjct: 231 PAWYPAQWQPCSRTC---GGGVQK-REVLCKQRM 260



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 25/117 (21%), Positives = 46/117 (39%), Gaps = 8/117 (6%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYEC----IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
            + ++ W+ C+ +CG G   R   C           V    C  +   +     + C +  
Sbjct: 1050 WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVA--KRPVDTQACNQQL 1107

Query: 414  CVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            CV W   +W  C+  C  P   V + R V+C  +     +   +C  + +P++T  C
Sbjct: 1108 CVEWAFSSWGQCNGPCIGPHLAV-QHRQVFCQTR-DGITLPSEQCSALPRPVSTQNC 1162



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 10/121 (8%)

Query: 358  YRLSEWTPCSVTC---GVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
            +  S W  C+  C    +    R   C  +    +   QC  +  P      + C   AC
Sbjct: 1111 WAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRP---VSTQNCWSEAC 1167

Query: 415  -VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADV 473
             VHW V  W  C+  C   G    + R V CV    NK V +  C    +P    +C   
Sbjct: 1168 SVHWRVSLWTLCTATC---GNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNIT 1224

Query: 474  P 474
            P
Sbjct: 1225 P 1225



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 7/53 (13%)

Query: 81  WSECSRTCGAGVSTQSRECNNP---EPVNNGNYCIGDR---SRYKVCNTDPCP 127
           +++CS +CG GV      C N    EP    N C+  R      K CN DPCP
Sbjct: 117 FTKCSESCGGGVQEAVVSCLNKQTREPAEE-NLCVTSRRPPQLLKSCNLDPCP 168



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 11/61 (18%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGN-------YCIGDR-SRYKVCNTDPC 126
           W P ++W  CSRTCG GV  Q RE    + + +G+       +C   + +  + C  D C
Sbjct: 233 WYP-AQWQPCSRTCGGGV--QKREVLCKQRMADGSFLELPETFCSASKPACQQACKKDDC 289

Query: 127 P 127
           P
Sbjct: 290 P 290



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 11/21 (52%), Positives = 15/21 (71%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S+W+ECS +CG G  T+S  C
Sbjct: 296 SDWTECSTSCGEGTQTRSAIC 316


>AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open reading
           frame 9 protein.
          Length = 1263

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 14/140 (10%)

Query: 338 NPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRV-VEQSQCYH 396
           NP  T       Q   + + +    +T CS +CG G       C+++  R   E++ C  
Sbjct: 92  NPDETDGLFGGLQDFDELYDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLC-- 149

Query: 397 IEPPRHQALMKQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYC---VDKVMNK- 451
           +   R   L+K C    C   W +G W+PCS  C +      + R V+C   + + MN+ 
Sbjct: 150 VTSRRPPQLLKSCNLDPCPARWEIGKWSPCSLTCGVG----LQTRDVFCSHLLSREMNET 205

Query: 452 -VVDDSECGQVIKPITTIKC 470
            ++ D  C Q  KP T   C
Sbjct: 206 VILADELCRQP-KPSTVQAC 224



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 7/94 (7%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRH--QALMKQCRKPAC- 414
           + + +W+PCS+TCGVG   R   C     R + ++     E  R    + ++ C +  C 
Sbjct: 171 WEIGKWSPCSLTCGVGLQTRDVFCSHLLSREMNETVILADELCRQPKPSTVQACNRFNCP 230

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKV 448
             W+   W PCS+ C   G  V K R V C  ++
Sbjct: 231 PAWYPAQWQPCSRTC---GGGVQK-REVLCKQRM 260



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 25/117 (21%), Positives = 46/117 (39%), Gaps = 8/117 (6%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYEC----IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
            + ++ W+ C+ +CG G   R   C           V    C  +   +     + C +  
Sbjct: 1050 WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVA--KRPVDTQACNQQL 1107

Query: 414  CVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            CV W   +W  C+  C  P   V + R V+C  +     +   +C  + +P++T  C
Sbjct: 1108 CVEWAFSSWGQCNGPCIGPHLAV-QHRQVFCQTR-DGITLPSEQCSALPRPVSTQNC 1162



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 10/121 (8%)

Query: 358  YRLSEWTPCSVTC---GVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
            +  S W  C+  C    +    R   C  +    +   QC  +  P      + C   AC
Sbjct: 1111 WAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRP---VSTQNCWSEAC 1167

Query: 415  -VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADV 473
             VHW V  W  C+  C   G    + R V CV    NK V +  C    +P    +C   
Sbjct: 1168 SVHWRVSLWTLCTATC---GNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNIT 1224

Query: 474  P 474
            P
Sbjct: 1225 P 1225



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 7/53 (13%)

Query: 81  WSECSRTCGAGVSTQSRECNNP---EPVNNGNYCIGDR---SRYKVCNTDPCP 127
           +++CS +CG GV      C N    EP    N C+  R      K CN DPCP
Sbjct: 117 FTKCSESCGGGVQEAVVSCLNKQTREPAEE-NLCVTSRRPPQLLKSCNLDPCP 168



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 11/61 (18%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGN-------YCIGDR-SRYKVCNTDPC 126
           W P ++W  CSRTCG GV  Q RE    + + +G+       +C   + +  + C  D C
Sbjct: 233 WYP-AQWQPCSRTCGGGV--QKREVLCKQRMADGSFLELPETFCSASKPACQQACKKDDC 289

Query: 127 P 127
           P
Sbjct: 290 P 290



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 11/21 (52%), Positives = 15/21 (71%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S+W+ECS +CG G  T+S  C
Sbjct: 296 SDWTECSTSCGEGTQTRSAIC 316


>AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open reading
           frame 9 protein.
          Length = 1263

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 14/140 (10%)

Query: 338 NPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRV-VEQSQCYH 396
           NP  T       Q   + + +    +T CS +CG G       C+++  R   E++ C  
Sbjct: 92  NPDETDGLFGGLQDFDELYDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLC-- 149

Query: 397 IEPPRHQALMKQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYC---VDKVMNK- 451
           +   R   L+K C    C   W +G W+PCS  C +      + R V+C   + + MN+ 
Sbjct: 150 VTSRRPPQLLKSCNLDPCPARWEIGKWSPCSLTCGVG----LQTRDVFCSHLLSREMNET 205

Query: 452 -VVDDSECGQVIKPITTIKC 470
            ++ D  C Q  KP T   C
Sbjct: 206 VILADELCRQP-KPSTVQAC 224



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 7/94 (7%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRH--QALMKQCRKPAC- 414
           + + +W+PCS+TCGVG   R   C     R + ++     E  R    + ++ C +  C 
Sbjct: 171 WEIGKWSPCSLTCGVGLQTRDVFCSHLLSREMNETVILADELCRQPKPSTVQACNRFNCP 230

Query: 415 VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKV 448
             W+   W PCS+ C   G  V K R V C  ++
Sbjct: 231 PAWYPAQWQPCSRTC---GGGVQK-REVLCKQRM 260



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 25/117 (21%), Positives = 46/117 (39%), Gaps = 8/117 (6%)

Query: 358  YRLSEWTPCSVTCGVGYTRRYYEC----IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
            + ++ W+ C+ +CG G   R   C           V    C  +   +     + C +  
Sbjct: 1050 WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVA--KRPVDTQACNQQL 1107

Query: 414  CVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            CV W   +W  C+  C  P   V + R V+C  +     +   +C  + +P++T  C
Sbjct: 1108 CVEWAFSSWGQCNGPCIGPHLAV-QHRQVFCQTR-DGITLPSEQCSALPRPVSTQNC 1162



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 10/121 (8%)

Query: 358  YRLSEWTPCSVTC---GVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
            +  S W  C+  C    +    R   C  +    +   QC  +  P      + C   AC
Sbjct: 1111 WAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRP---VSTQNCWSEAC 1167

Query: 415  -VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADV 473
             VHW V  W  C+  C   G    + R V CV    NK V +  C    +P    +C   
Sbjct: 1168 SVHWRVSLWTLCTATC---GNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNIT 1224

Query: 474  P 474
            P
Sbjct: 1225 P 1225



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 7/53 (13%)

Query: 81  WSECSRTCGAGVSTQSRECNNP---EPVNNGNYCIGDR---SRYKVCNTDPCP 127
           +++CS +CG GV      C N    EP    N C+  R      K CN DPCP
Sbjct: 117 FTKCSESCGGGVQEAVVSCLNKQTREPAEE-NLCVTSRRPPQLLKSCNLDPCP 168



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 11/61 (18%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGN-------YCIGDR-SRYKVCNTDPC 126
           W P ++W  CSRTCG GV  Q RE    + + +G+       +C   + +  + C  D C
Sbjct: 233 WYP-AQWQPCSRTCGGGV--QKREVLCKQRMADGSFLELPETFCSASKPACQQACKKDDC 289

Query: 127 P 127
           P
Sbjct: 290 P 290



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 11/21 (52%), Positives = 15/21 (71%)

Query: 79  SEWSECSRTCGAGVSTQSREC 99
           S+W+ECS +CG G  T+S  C
Sbjct: 296 SDWTECSTSCGEGTQTRSAIC 316


>AL359934-1|CAB95770.1|  432|Homo sapiens ADAMTS7, alternatively
           spliced product protein.
          Length = 432

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 15/119 (12%)

Query: 357 SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEP-PRHQALMKQCRKPACV 415
           ++    W+ CS +CG G + R  +C+D   R +   + +H +P P      + C    C+
Sbjct: 211 TWHSGNWSKCSRSCGGGSSVRDVQCVDT--RDLRPLRPFHCQPGPAKPPAHRPCGAQPCL 268

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
            W+  +W  CS+ C   GE+   +R V C +  +        C + ++P TT  C   P
Sbjct: 269 SWYTSSWRECSEACG-GGEQ---QRLVTCPEPGL--------CEEALRPNTTRPCNTHP 315



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 12/90 (13%)

Query: 357 SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           S++   W+ CS TCG+G   R   C            C    P       ++C    C  
Sbjct: 160 SWQAGNWSECSTTCGLGAVWRPVRCSSG-----RDEDC---APAGRPQPARRCHLRPCAT 211

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYCVD 446
           W  G W+ CS+ C   G  V   R V CVD
Sbjct: 212 WHSGNWSKCSRSCG-GGSSV---RDVQCVD 237



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 15/115 (13%)

Query: 357 SYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           S+  S W  CS  CG G  +R   C        E   C     P      + C    C  
Sbjct: 269 SWYTSSWRECSEACGGGEQQRLVTC-------PEPGLCEEALRPN---TTRPCNTHPCTQ 318

Query: 417 WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDS-ECGQVIKPITTIKC 470
           W VG W  CS  C   G  V + R V CV+       +DS +CG    P ++  C
Sbjct: 319 WVVGPWGQCSAPC---GGGV-QRRLVKCVNTQTGLPEEDSDQCGHEAWPESSRPC 369



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 41/126 (32%), Positives = 48/126 (38%), Gaps = 14/126 (11%)

Query: 5   ASQCHLQFGA--EAGLCSKLSELCEHLWCLVDNVC--TTMMRPAAPGTTCGPDMWCQNQT 60
           A +CHL+  A   +G  SK S  C     + D  C  T  +RP  P   C P        
Sbjct: 201 ARRCHLRPCATWHSGNWSKCSRSCGGGSSVRDVQCVDTRDLRPLRP-FHCQPGP----AK 255

Query: 61  CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKV 120
             A  P  A     W   S W ECS  CG G   Q R    PEP         + +R   
Sbjct: 256 PPAHRPCGAQPCLSWYT-SSWRECSEACGGG--EQQRLVTCPEPGLCEEALRPNTTR--P 310

Query: 121 CNTDPC 126
           CNT PC
Sbjct: 311 CNTHPC 316



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 2/46 (4%)

Query: 353 HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQ--SQCYH 396
           H    + +  W  CS  CG G  RR  +C++    + E+   QC H
Sbjct: 314 HPCTQWVVGPWGQCSAPCGGGVQRRLVKCVNTQTGLPEEDSDQCGH 359


>U12471-1|AAA21127.1|   59|Homo sapiens thrombospondin-1p180
           protein.
          Length = 59

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 61  CVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
           C  R       D GW PWSEW+ CS +CG G+  + R C++
Sbjct: 5   CCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDS 45


>DQ364570-1|ABC88384.1|  127|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif 4 alternative splice var
           protein.
          Length = 127

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 21/57 (36%), Positives = 31/57 (54%)

Query: 198 MCISGVCYKVGCDWIVDSDVEEDACGVCGGDGTACKTVQGIYTKGTTRQSGFSEVAI 254
           +C+ G C   GCD I+ S  + D C VCGGDG+ C    G + K     +  S++A+
Sbjct: 1   VCVQGRCIHAGCDRIIGSKKKFDKCMVCGGDGSGCSKQSGSFRKFRCGTAWGSQLAL 57


>BC027478-1|AAH27478.1|  424|Homo sapiens ADAMTSL4 protein protein.
          Length = 424

 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQH---QRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           +   EWT CS +CG G   R  +C  +       V   +C H+  P    + + C+   C
Sbjct: 77  WEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLPRPN---ITQSCQLRLC 133

Query: 415 VHWWVGA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            HW VG+ W+ CS  C   G+   + R V CV    ++ V + EC
Sbjct: 134 GHWEVGSPWSQCSVRCGR-GQ---RSRQVRCVGNNGDE-VSEQEC 173



 Score = 48.4 bits (110), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 14/116 (12%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQ---HQRVVEQSQCYHIEPPRHQALMKQCRKPACV-HWW 418
           W  CS  CG G  RR   C+ +      V   S C H+  PR  AL + C+  AC   W+
Sbjct: 269 WGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHL--PRPPAL-QPCQGQACQDRWF 325

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
              W+PCS+ C    +  T+ R V C+    N+ +  + C   ++P     C   P
Sbjct: 326 STPWSPCSRSC----QGGTQTREVQCLS--TNQTL-STRCPPQLRPSRKRPCNSQP 374



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 12/110 (10%)

Query: 366 CSVTCGVGYTRRYYECIDQH--QRVVEQSQCYHIEPPRHQALMKQCRKPACVHWW-VGAW 422
           CS +CG G  R  + CI +   + + E+S      PP   A  + C    C  +W  G W
Sbjct: 26  CSASCGKGVWRPIFLCISRESGEELDERSCAAGARPP---ASPEPCHGTPCPPYWEAGEW 82

Query: 423 NPCSKLCHMPGEEVTKERSVYCVDKV--MNKVVDDSECGQVIKPITTIKC 470
             CS+ C  PG   T+ R + C  +       V    CG + +P  T  C
Sbjct: 83  TSCSRSCG-PG---TQHRQLQCRQEFGGGGSSVPPERCGHLPRPNITQSC 128



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           S W+ CSV CG G   R   C+  +   V + +C    PP+  +       P    W+  
Sbjct: 140 SPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECAS-GPPQPPSREACDMGPCTTAWFHS 198

Query: 421 AW-NPCSKLCHMPGEEVTKERSVYCV 445
            W + CS  C   G  + + RSV C+
Sbjct: 199 DWSSKCSAEC---GTGI-QRRSVVCL 220



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 20/124 (16%)

Query: 361 SEWTP-CSVTCGVGYTRRYYECIDQHQRV----------VEQSQCYHIEPPRHQAL-MKQ 408
           S+W+  CS  CG G  RR   C+     +            QS      PP  +A  +  
Sbjct: 198 SDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDMRACSLGP 257

Query: 409 CRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNK--VVDDSECGQVIKPIT 466
           C +     W+ G W  CS  C       T+ R + CV K+  +  V   S C  + +P  
Sbjct: 258 CERTW--RWYTGPWGECSSEC----GSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPPA 311

Query: 467 TIKC 470
              C
Sbjct: 312 LQPC 315



 Score = 33.1 bits (72), Expect = 2.2
 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 73  GGWGPWSEWSECSRTCGAGVSTQSREC--NNPEPVNNGNYCIG--DRSRYKVCNTDPC 126
           G W   S WS+CS  CG G  ++   C  NN + V+      G       + C+  PC
Sbjct: 134 GHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREACDMGPC 191



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 81  WSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
           WS CSR+C  G  T+  +C +     +       R SR + CN+ PC
Sbjct: 329 WSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRKRPCNSQPC 375



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 63  ARTP-SPAPRDGGWGP--WS--EWSECSRTCGAGVSTQSREC 99
           AR P SP P  G   P  W   EW+ CSR+CG G   +  +C
Sbjct: 59  ARPPASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQC 100


>AF217974-1|AAG17217.1|  237|Homo sapiens unknown protein.
          Length = 237

 Score = 48.4 bits (110), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 14/116 (12%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQ---HQRVVEQSQCYHIEPPRHQALMKQCRKPACV-HWW 418
           W  CS  CG G  RR   C+ +      V   S C H+  PR  AL + C+  AC   W+
Sbjct: 82  WGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHL--PRPPAL-QPCQGQACQDRWF 138

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVP 474
              W+PCS+ C    +  T+ R V C+    N+ +  + C   ++P     C   P
Sbjct: 139 STPWSPCSRSC----QGGTQTREVQCLS--TNQTL-STRCPPQLRPSRKRPCNSQP 187



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 20/124 (16%)

Query: 361 SEWTP-CSVTCGVGYTRRYYECIDQHQRV----------VEQSQCYHIEPPRHQAL-MKQ 408
           S+W+  CS  CG G  RR   C+     +            QS      PP  +A  +  
Sbjct: 11  SDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDMRACSLGP 70

Query: 409 CRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNK--VVDDSECGQVIKPIT 466
           C +     W+ G W  CS  C       T+ R + CV K+  +  V   S C  + +P  
Sbjct: 71  CERTW--RWYTGPWGECSSEC----GSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPPA 124

Query: 467 TIKC 470
              C
Sbjct: 125 LQPC 128



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 81  WSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
           WS CSR+C  G  T+  +C +     +       R SR + CN+ PC
Sbjct: 142 WSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRKRPCNSQPC 188


>AL359513-1|CAH71657.1|  852|Homo sapiens thrombospondin, type I,
           domain containing 1 protein.
          Length = 852

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 2/58 (3%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPS 132
           WG W  WS+CS TCG GV  + R C    P  +   C G      +C+ + C   +PS
Sbjct: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEECAAFQPS 398


>AL354919-4|CAM12877.1|  847|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 847

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 2/56 (3%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           D  WGPW+ WS CS+TC  G   + R C        G  C G     K C+   CP
Sbjct: 413 DSKWGPWNAWSLCSKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCP 466



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 5/84 (5%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    +T      +  P +G W  W  W  CS +C  G   +SR+C+   P  
Sbjct: 335 GTLCSGPL---RETRPCNNSATCPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPA- 390

Query: 107 NGNYCIGDRSRYKVCNTDPCPINE 130
               C G  +  + C+   CP  +
Sbjct: 391 -WATCTGALTDTRECSNLECPATD 413



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 9/68 (13%)

Query: 62  VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
           +A+T  PA  +     WS WS CS TCG G+  ++R C +  P   G  C G     + C
Sbjct: 297 MAQTGDPAAEE-----WSPWSVCSLTCGQGLQVRTRSCVS-SPY--GTLCSGPLRETRPC 348

Query: 122 NTD-PCPI 128
           N    CP+
Sbjct: 349 NNSATCPV 356



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 30/113 (26%), Positives = 42/113 (37%), Gaps = 10/113 (8%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W+ CS+TCG G   R   C+      +         P  + A    C  P    W  W
Sbjct: 309 SPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSA---TC--PVEGQWLEW 363

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVY--CVDKVMNKVVDDSECGQVIKPITTIK 469
            G W PCS  C    ++ +++ SV           + D  EC  +  P T  K
Sbjct: 364 -GPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSK 415


>AL354919-1|CAM12874.1| 1466|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 1466

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 2/56 (3%)

Query: 72  DGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           D  WGPW+ WS CS+TC  G   + R C        G  C G     K C+   CP
Sbjct: 408 DSKWGPWNAWSLCSKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCP 461



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 5/84 (5%)

Query: 47  GTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVN 106
           GT C   +    +T      +  P +G W  W  W  CS +C  G   +SR+C+   P  
Sbjct: 330 GTLCSGPL---RETRPCNNSATCPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPA- 385

Query: 107 NGNYCIGDRSRYKVCNTDPCPINE 130
               C G  +  + C+   CP  +
Sbjct: 386 -WATCTGALTDTRECSNLECPATD 408



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 9/68 (13%)

Query: 62  VARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVC 121
           +A+T  PA  +     WS WS CS TCG G+  ++R C +  P   G  C G     + C
Sbjct: 292 MAQTGDPAAEE-----WSPWSVCSLTCGQGLQVRTRSCVS-SPY--GTLCSGPLRETRPC 343

Query: 122 NTD-PCPI 128
           N    CP+
Sbjct: 344 NNSATCPV 351



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 30/113 (26%), Positives = 42/113 (37%), Gaps = 10/113 (8%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W+ CS+TCG G   R   C+      +         P  + A    C  P    W  W
Sbjct: 304 SPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSA---TC--PVEGQWLEW 358

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVY--CVDKVMNKVVDDSECGQVIKPITTIK 469
            G W PCS  C    ++ +++ SV           + D  EC  +  P T  K
Sbjct: 359 -GPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSK 410


>AB044385-1|BAA96553.1|  852|Homo sapiens transmembrane molecule
           with thrombospondin module protein.
          Length = 852

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 2/58 (3%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPS 132
           WG W  WS+CS TCG GV  + R C    P  +   C G      +C+ + C   +PS
Sbjct: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEECAAFQPS 398


>BC028145-1|AAH28145.1|  401|Homo sapiens Unknown (protein for
           IMAGE:5217975) protein.
          Length = 401

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 31  CLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGA 90
           C   N  T   + + P   C        + C    PS +  D GW PWSEW+ CS +CG 
Sbjct: 339 CHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSA-DDGWSPWSEWTSCSTSCGN 397

Query: 91  GV 92
           G+
Sbjct: 398 GI 399


>AL353895-4|CAI14853.2|  470|Homo sapiens ADAMTS-like 1 protein.
          Length = 470

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 33/120 (27%), Positives = 57/120 (47%), Gaps = 9/120 (7%)

Query: 297 YFVAGAQAIYERDRDWEKVRISGPLAEDIKVYQRIFRGRHRNPGVTYQYTVDKQRLHKKH 356
           + V  +   +++  D E +R++GPL  D  V  R       +   T Q+   +  +H+  
Sbjct: 34  FLVDNSSVDFQKFPDKEILRMAGPLTADFIVKIR----NSGSADSTVQFIFYQPIIHR-- 87

Query: 357 SYRLSEWTPCSVTCGVGYTRRYYECID-QHQRVVEQSQC-YHIEPPRHQALMKQCRKPAC 414
            +R +++ PCS TCG GY     EC D +  RVV    C Y+ E  + +  +++C    C
Sbjct: 88  -WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPC 146



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 14/138 (10%)

Query: 343 YQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIE 398
           Y+  +     H    +  + WT CS +CG G   R   C+++    H   VE+ +C +  
Sbjct: 152 YKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKCMY-- 209

Query: 399 PPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            P+   + + C    C  W    W+PC+  C   G+ + + R V C+D   ++ +    C
Sbjct: 210 TPK-MPIAQPCNIFDCPKWLAQEWSPCTVTC---GQGL-RYRVVLCID---HRGMHTGGC 261

Query: 459 GQVIKPITTIKCADVPAC 476
               KP    +C     C
Sbjct: 262 SPKTKPHIKEECIVPTPC 279



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 5/95 (5%)

Query: 338 NPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQR-VVEQSQCYH 396
           NP  T       Q   + + +    +T CS +CG G       C+++  R   E++ C  
Sbjct: 378 NPDETDGLFGGLQDFDELYDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLC-- 435

Query: 397 IEPPRHQALMKQCRKPACV--HWWVGAWNPCSKLC 429
           +   R   L+K C    C        AWN C+ LC
Sbjct: 436 VTSRRPPQLLKSCNLDPCPARSSIDSAWNACNVLC 470



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 7/53 (13%)

Query: 81  WSECSRTCGAGVSTQSRECNNP---EPVNNGNYCIGDR---SRYKVCNTDPCP 127
           +++CS +CG GV      C N    EP    N C+  R      K CN DPCP
Sbjct: 403 FTKCSESCGGGVQEAVVSCLNKQTREPAEE-NLCVTSRRPPQLLKSCNLDPCP 454



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 8/60 (13%)

Query: 79  SEWSECSRTCGAGVSTQSRECNN--PEPVNNGNYC------IGDRSRYKVCNTDPCPINE 130
           +++  CS TCG G    S EC +     V    YC      I  + + + CN DPCP ++
Sbjct: 91  TDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPASD 150


>AF251058-1|AAK34948.1|  417|Homo sapiens thrombospondin protein.
          Length = 417

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 14/138 (10%)

Query: 343 YQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQ----HQRVVEQSQCYHIE 398
           Y+  +     H    +  + WT CS +CG G   R   C+++    H   VE+ +C +  
Sbjct: 99  YKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKCMY-- 156

Query: 399 PPRHQALMKQCRKPACVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSEC 458
            P+   + + C    C  W    W+PC+  C   G+ + + R V C+D   ++ +    C
Sbjct: 157 TPK-MPIAQPCNIFDCPKWLAQEWSPCTVTC---GQGL-RYRVVLCID---HRGMHTGGC 208

Query: 459 GQVIKPITTIKCADVPAC 476
               KP    +C     C
Sbjct: 209 SPKTKPHIKEECIVPTPC 226



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 2/61 (3%)

Query: 356 HSYRLSEWTPCSVTCGVGYTRRYYECID-QHQRVVEQSQC-YHIEPPRHQALMKQCRKPA 413
           H +R +++ PCS TCG GY     EC D +  RVV    C Y+ E  + +  +++C    
Sbjct: 33  HRWRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDP 92

Query: 414 C 414
           C
Sbjct: 93  C 93



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 5/95 (5%)

Query: 338 NPGVTYQYTVDKQRLHKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQR-VVEQSQCYH 396
           NP  T       Q   + + +    +T CS +CG G       C+++  R   E++ C  
Sbjct: 325 NPDETDGLFGGLQDFDELYDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLC-- 382

Query: 397 IEPPRHQALMKQCRKPACV--HWWVGAWNPCSKLC 429
           +   R   L+K C    C        AWN C+ LC
Sbjct: 383 VTSRRPPQLLKSCNLDPCPARSSIDSAWNACNVLC 417



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 7/53 (13%)

Query: 81  WSECSRTCGAGVSTQSRECNNP---EPVNNGNYCIGDR---SRYKVCNTDPCP 127
           +++CS +CG GV      C N    EP    N C+  R      K CN DPCP
Sbjct: 350 FTKCSESCGGGVQEAVVSCLNKQTREPAEE-NLCVTSRRPPQLLKSCNLDPCP 401



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 8/60 (13%)

Query: 79  SEWSECSRTCGAGVSTQSRECNN--PEPVNNGNYC------IGDRSRYKVCNTDPCPINE 130
           +++  CS TCG G    S EC +     V    YC      I  + + + CN DPCP ++
Sbjct: 38  TDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPASD 97


>AY692423-1|AAW47396.1|  270|Homo sapiens ADAMTS6 variant 2 protein.
          Length = 270

 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 5/113 (4%)

Query: 360 LSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWV 419
           + +W  CS TC  G   R   CI +     E++  Y           + C   +C   WV
Sbjct: 58  IGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPVEKEPCNNQSCPPQWV 117

Query: 420 GA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCA 471
              W+ C+  C  PG    K R V C    ++K    ++C +  KP   I+C+
Sbjct: 118 ALDWSECTPKCG-PG---FKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCS 166



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 12/90 (13%)

Query: 363 WTPCSVTCGVGYTRRYYEC--IDQHQRVVEQSQCY-HIEPPRHQALMKQCRKPACV-HWW 418
           W+ CS TC  G  R+   C  +D +  +V+ + C    +PP +Q   + C    C   W+
Sbjct: 2   WSECSATCAGGVQRQEVVCKRLDDNS-IVQNNYCDPDSKPPENQ---RACNTEPCPPEWF 57

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKV 448
           +G W  CSK C    +   + R+V C+ K+
Sbjct: 58  IGDWLECSKTC----DGGMRTRAVLCIRKI 83



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 5/52 (9%)

Query: 81  WSECSRTCGAGVSTQSRECN--NPEPVNNGNYCIGDR---SRYKVCNTDPCP 127
           WSECS TC  GV  Q   C   +   +   NYC  D       + CNT+PCP
Sbjct: 2   WSECSATCAGGVQRQEVVCKRLDDNSIVQNNYCDPDSKPPENQRACNTEPCP 53



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 13/112 (11%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQC-YHIEPP-RHQALMKQCRKPACVHWW 418
           +W+ C+  CG G+  R   C      +    +QC    +PP R +  + +C  P    W 
Sbjct: 120 DWSECTPKCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSLGRCPPP---RWV 176

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            G W  CS  C + G+++   R+V C+          S+C + ++P +  +C
Sbjct: 177 TGDWGQCSAQCGL-GQQM---RTVQCLSYTGQA---SSDCLETVRPPSMQQC 221


>AK131039-1|BAC85480.1|  288|Homo sapiens protein ( Homo sapiens
           cDNA FLJ29005 fis, clone TST07872. ).
          Length = 288

 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 5/113 (4%)

Query: 360 LSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWV 419
           + +W  CS TC  G   R   CI +     E++  Y           + C   +C   WV
Sbjct: 76  IGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPVEKEPCNNQSCPPQWV 135

Query: 420 GA-WNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCA 471
              W+ C+  C  PG    K R V C    ++K    ++C +  KP   I+C+
Sbjct: 136 ALDWSECTPKCG-PG---FKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCS 184



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 13/112 (11%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQH-QRVVEQSQC-YHIEPP-RHQALMKQCRKPACVHWW 418
           +W+ C+  CG G+  R   C      +    +QC    +PP R +  + +C  P    W 
Sbjct: 138 DWSECTPKCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSLGRCPPP---RWV 194

Query: 419 VGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
            G W  CS  C + G+++   R+V C+          S+C + ++P +  +C
Sbjct: 195 TGDWGQCSAQCGL-GQQM---RTVQCLSYTGQA---SSDCLETVRPPSMQQC 239



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 9/63 (14%)

Query: 388 VVEQSQCY-HIEPPRHQALMKQCRKPACV-HWWVGAWNPCSKLCHMPGEEVTKERSVYCV 445
           +V+ + C    +PP +Q   + C    C   W++G W  CSK C    +   + R+V C+
Sbjct: 46  IVQNNYCDPDSKPPENQ---RACNTEPCPPEWFIGDWLECSKTC----DGGMRTRAVLCI 98

Query: 446 DKV 448
            K+
Sbjct: 99  RKI 101


>AK129873-1|BAC85245.1|  226|Homo sapiens protein ( Homo sapiens
           cDNA FLJ26363 fis, clone HRT05360, highly similar to
           ADAM-TS 1 PRECURSOR (EC 3.4.24.-). ).
          Length = 226

 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 17/50 (34%), Positives = 27/50 (54%)

Query: 353 HKKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRH 402
           H    ++L EW+ CS TCG GY +R  +C+     V+    C  ++ P+H
Sbjct: 166 HPCPQWQLGEWSSCSKTCGKGYKKRSLKCLSHDGGVLSHESCDPLKKPKH 215



 Score = 44.0 bits (99), Expect = 0.001
 Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 10/110 (9%)

Query: 367 SVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAWNPCS 426
           S TC +G+ RR  EC D + +    S+C     P   A  + C    C  W +G W+ CS
Sbjct: 126 SQTCELGWQRRLVECRDINGQPA--SECAKEVKP---ASTRPCADHPCPQWQLGEWSSCS 180

Query: 427 KLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
           K C   G+   K+RS+ C+      V+    C  + KP   I    +  C
Sbjct: 181 KTC---GKGY-KKRSLKCLSH-DGGVLSHESCDPLKKPKHFIDFCTMAEC 225



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 11/20 (55%), Positives = 14/20 (70%)

Query: 80  EWSECSRTCGAGVSTQSREC 99
           EWS CS+TCG G   +S +C
Sbjct: 175 EWSSCSKTCGKGYKKRSLKC 194


>BC016451-1|AAH16451.1|  364|Homo sapiens ADAMTS3 protein protein.
          Length = 364

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 12/123 (9%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC-IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVH 416
           + L  W+ CS  CG G+    Y C      ++V +S C   + P+   + + C    C H
Sbjct: 8   WALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPK--PIRRMCNIQECTH 65

Query: 417 --WWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVM---NKVVDDSECGQVIKPITTIKCA 471
             W    W  C+K C   G ++   R+V C+  ++   N+ V    C    +P +   C 
Sbjct: 66  PLWVAEEWEHCTKTCGSSGYQL---RTVRCLQPLLDGTNRSVHSKYC-MGDRPESRRPCN 121

Query: 472 DVP 474
            VP
Sbjct: 122 RVP 124



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 7/67 (10%)

Query: 80  EWSECSRTCG-AGVSTQSRECNNP--EPVN---NGNYCIGDR-SRYKVCNTDPCPINEPS 132
           EW  C++TCG +G   ++  C  P  +  N   +  YC+GDR    + CN  PCP    +
Sbjct: 72  EWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESRRPCNRVPCPAQWKT 131

Query: 133 FREVQCS 139
               +CS
Sbjct: 132 GPWSECS 138



 Score = 39.1 bits (87), Expect = 0.033
 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 14/89 (15%)

Query: 362 EWTPCSVTCGV-GYTRRYYECI----DQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-V 415
           EW  C+ TCG  GY  R   C+    D   R V    C    P       + C +  C  
Sbjct: 72  EWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESR----RPCNRVPCPA 127

Query: 416 HWWVGAWNPCSKLCHMPGEEVTKERSVYC 444
            W  G W+ CS  C     E T+ R V C
Sbjct: 128 QWKTGPWSECSVTC----GEGTEVRQVLC 152



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 14/91 (15%)

Query: 41  MRPAAPGTTCGP-DMWCQNQTCVARTPS---PAPRDGGWGPWSEWSECSRTCGAGVSTQS 96
           ++P   GT       +C      +R P    P P     GPWSE   CS TCG G   + 
Sbjct: 93  LQPLLDGTNRSVHSKYCMGDRPESRRPCNRVPCPAQWKTGPWSE---CSVTCGEGTEVRQ 149

Query: 97  RECNNPEPVNNGNYCIGDR-SRYKVCNTDPC 126
             C        G++C G++    + C   PC
Sbjct: 150 VLC------RAGDHCDGEKPESVRACQLPPC 174


>AB023177-1|BAA76804.2| 1502|Homo sapiens KIAA0960 protein protein.
          Length = 1502

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 68  PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           P  +D     +S WSECS+TCG+G+  ++R    P P   G+ C  + + ++VC + PC 
Sbjct: 35  PCQQDCIVSEFSAWSECSKTCGSGLQHRTRHVVAP-PQFGGSGC-PNLTEFQVCQSSPCE 92

Query: 128 INE 130
             E
Sbjct: 93  AEE 95



 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 1/44 (2%)

Query: 68  PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC 111
           P P D     WS WS CS++CG+GV  +S+     +P N G  C
Sbjct: 876 PCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLRE-KPYNGGRPC 918



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 6/73 (8%)

Query: 55   WCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSRECNNPEPVNNGNYCIG 113
            W  N +C+   P           WS WSECS+TCG  G   + R    P    +G  C  
Sbjct: 1118 WQMNTSCMVECPVNCQLSD----WSPWSECSQTCGLTGKMIRRRTVTQPFQ-GDGRPCPS 1172

Query: 114  DRSRYKVCNTDPC 126
               + K C   PC
Sbjct: 1173 LMDQSKPCPVKPC 1185



 Score = 38.3 bits (85), Expect = 0.058
 Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 15/111 (13%)

Query: 359  RLSEWTP---CSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACV 415
            +LS+W+P   CS TCG+  T +      + + V +  Q      P      K C    C 
Sbjct: 1133 QLSDWSPWSECSQTCGL--TGKMI----RRRTVTQPFQGDGRPCPSLMDQSKPCPVKPCY 1186

Query: 416  HWWVGAWNPCSKLCHMPGEEVTKERSVYCV-----DKVMNKVVDDSECGQV 461
             W  G W+PC       GE  T+ R++ CV         +KVVD+  C  +
Sbjct: 1187 RWQYGQWSPCQVQEAQCGEG-TRTRNISCVVSDGSADDFSKVVDEEFCADI 1236



 Score = 37.9 bits (84), Expect = 0.077
 Identities = 18/90 (20%), Positives = 41/90 (45%), Gaps = 7/90 (7%)

Query: 356  HSYRLSEWTPCSVT----CGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRK 411
            + Y +++W+ C ++    CG G   R  +C+    + V+   C  +   ++  +   C  
Sbjct: 1067 YDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEALGLEKNWQMNTSCMV 1126

Query: 412  PACVHWWVGAWNP---CSKLCHMPGEEVTK 438
               V+  +  W+P   CS+ C + G+ + +
Sbjct: 1127 ECPVNCQLSDWSPWSECSQTCGLTGKMIRR 1156



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 370 CGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLC 429
           CG GY  +   C DQ+ R+VE S+C +      +A +  C     +  W   W+ CSK C
Sbjct: 839 CGQGYRYQAMACYDQNGRLVETSRC-NSHGYIEEACIIPCPSDCKLSEW-SNWSRCSKSC 896



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 8/69 (11%)

Query: 67  SPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPV-----NNGNYCIGDRSRYKV- 120
           +P P+D     WS WS CS TC +G +T+ ++      +       G  C    +  +V 
Sbjct: 474 APCPKDCVLSTWSTWSSCSHTC-SGKTTEGKQIRARSILAYAGEEGGIRCPNSSALQEVR 532

Query: 121 -CNTDPCPI 128
            CN  PC +
Sbjct: 533 SCNEHPCTV 541



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 8/62 (12%)

Query: 372 VGYTRRYYECIDQHQRVVEQSQCYHIEPP---RHQALMKQCRKPACVHWWVGAWNPCSKL 428
           +GY  R   CI++  +  + S C   + P   +   + K+C+    V  W   W+PCSK 
Sbjct: 166 IGYQTREVMCINKTGKAADLSFCQQEKLPMTFQSCVITKECQ----VSEW-SEWSPCSKT 220

Query: 429 CH 430
           CH
Sbjct: 221 CH 222


>BC041974-1|AAH41974.1|  257|Homo sapiens SPON1 protein protein.
          Length = 257

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           PWSEWS+CS TCG G+ T+ R   +   + +   C  D  + + C    CPI+
Sbjct: 69  PWSEWSDCSVTCGKGMRTRQRMLKSLAELGD---CNEDLEQVEKCMLPECPID 118



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 1/50 (2%)

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           PW+ WSEC++ CG G+  +          +    C  D+   + CN  PC
Sbjct: 209 PWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSC-KDKKEIRACNVHPC 257



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 4/50 (8%)

Query: 78  WSEWSECSRTCGAGVSTQSRECN-NPEPVNNGNYCIGDRSRYKVCNTDPC 126
           W EW ECS TCG G+  + R    NP    +G+ C  + S+ + C    C
Sbjct: 14  WGEWDECSATCGMGMKKRHRMIKMNPA---DGSMCKAETSQAEKCMMPEC 60



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 3/68 (4%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGA 421
           EW  CS TCG+G  +R +  I  +    + S C        + +M +C    C+      
Sbjct: 16  EWDECSATCGMGMKKR-HRMIKMNP--ADGSMCKAETSQAEKCMMPECHTIPCLLSPWSE 72

Query: 422 WNPCSKLC 429
           W+ CS  C
Sbjct: 73  WSDCSVTC 80



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 3/60 (5%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQ 137
           WS+WSEC+++CG G   ++R     EP   G  C  +  + K C    C +  PS ++++
Sbjct: 124 WSQWSECNKSCGKGHVIRTRMI-QMEPQFGGAPC-PETVQRKKCRIRKC-LRNPSIQKLR 180



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           SEW+ CSVTCG G   R        + + E   C        + ++ +C     +  W  
Sbjct: 71  SEWSDCSVTCGKGMRTRQ----RMLKSLAELGDCNEDLEQVEKCMLPECPIDCELTEW-S 125

Query: 421 AWNPCSKLC 429
            W+ C+K C
Sbjct: 126 QWSECNKSC 134


>BC019825-1|AAH19825.1|  259|Homo sapiens SPON1 protein protein.
          Length = 259

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           PWSEWS+CS TCG G+ T+ R   +   + +   C  D  + + C    CPI+
Sbjct: 71  PWSEWSDCSVTCGKGMRTRQRMLKSLAELGD---CNEDLEQVEKCMLPECPID 120



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 1/50 (2%)

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           PW+ WSEC++ CG G+  +          +    C  D+   + CN  PC
Sbjct: 211 PWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSC-KDKKEIRACNVHPC 259



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 4/50 (8%)

Query: 78  WSEWSECSRTCGAGVSTQSRECN-NPEPVNNGNYCIGDRSRYKVCNTDPC 126
           W EW ECS TCG G+  + R    NP    +G+ C  + S+ + C    C
Sbjct: 16  WGEWDECSATCGMGMKKRHRMIKMNPA---DGSMCKAETSQAEKCMMPEC 62



 Score = 37.1 bits (82), Expect = 0.13
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 3/60 (5%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQ 137
           WS+WSEC+++CG G   ++R     EP   G  C  +  + K C    C +  PS ++++
Sbjct: 126 WSQWSECNKSCGKGHVIRTR-MTQMEPQFGGAPC-PETVQRKKCRIRKC-LRNPSIQKLR 182



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 3/68 (4%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGA 421
           EW  CS TCG+G  +R +  I  +    + S C        + +M +C    C+      
Sbjct: 18  EWDECSATCGMGMKKR-HRMIKMNP--ADGSMCKAETSQAEKCMMPECHTIPCLLSPWSE 74

Query: 422 WNPCSKLC 429
           W+ CS  C
Sbjct: 75  WSDCSVTC 82



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           SEW+ CSVTCG G   R        + + E   C        + ++ +C     +  W  
Sbjct: 73  SEWSDCSVTCGKGMRTRQ----RMLKSLAELGDCNEDLEQVEKCMLPECPIDCELTEW-S 127

Query: 421 AWNPCSKLC 429
            W+ C+K C
Sbjct: 128 QWSECNKSC 136


>AK074803-1|BAC11217.1|  807|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90322 fis, clone NT2RP2001755, highly similar to
           Rattus norvegicus f-spondin mRNA. ).
          Length = 807

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           PWSEWS+CS TCG G+ T+ R   +   + +   C  D  + + C    CPI+
Sbjct: 619 PWSEWSDCSVTCGKGMRTRQRMLKSLAELGD---CNEDLEQVEKCMLPECPID 668



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 1/50 (2%)

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           PW+ WSEC++ CG G+  +          +    C  D+   + CN  PC
Sbjct: 759 PWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSC-KDKKEIRACNVHPC 807



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 3/60 (5%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQ 137
           WS+WSEC+++CG G   ++R     EP   G  C  +  + K C    C +  PS ++++
Sbjct: 674 WSQWSECNKSCGKGHVIRTRMI-QMEPQFGGAPC-PETVQRKKCRIRKC-LRNPSIQKLR 730



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 12/72 (16%)

Query: 78  WSEWSECSRTCGAGVSTQSRECN-NPEPVNNGNYCIGDRSRYK-----VCNTDPC---PI 128
           W EW E S TCG G+  + R    NP    +G+ C  + S+ +      C+T PC   P 
Sbjct: 564 WGEWDEYSATCGMGMKKRHRMIKMNPA---DGSMCKAETSQAEKRMMPECHTIPCLLSPW 620

Query: 129 NEPSFREVQCSR 140
           +E S   V C +
Sbjct: 621 SEWSDCSVTCGK 632



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           SEW+ CSVTCG G   R        + + E   C        + ++ +C     +  W  
Sbjct: 621 SEWSDCSVTCGKGMRTRQ----RMLKSLAELGDCNEDLEQVEKCMLPECPIDCELTEW-S 675

Query: 421 AWNPCSKLC 429
            W+ C+K C
Sbjct: 676 QWSECNKSC 684



 Score = 31.9 bits (69), Expect = 5.1
 Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 4/70 (5%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC-YHIEPPRHQALMKQCRKPACVHWWVGA 421
           W+PCS++CG+G   R    + Q     + S C    E      + ++C   +C+    G 
Sbjct: 510 WSPCSISCGMGMRSR-ERYVKQFPE--DGSVCTLPTEETEKCTVNEECSPSSCLMTEWGE 566

Query: 422 WNPCSKLCHM 431
           W+  S  C M
Sbjct: 567 WDEYSATCGM 576



 Score = 31.5 bits (68), Expect = 6.7
 Identities = 18/68 (26%), Positives = 28/68 (41%), Gaps = 3/68 (4%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGA 421
           EW   S TCG+G  +R +  I  +    + S C        + +M +C    C+      
Sbjct: 566 EWDEYSATCGMGMKKR-HRMIKMNP--ADGSMCKAETSQAEKRMMPECHTIPCLLSPWSE 622

Query: 422 WNPCSKLC 429
           W+ CS  C
Sbjct: 623 WSDCSVTC 630



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 35/152 (23%), Positives = 59/152 (38%), Gaps = 25/152 (16%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQ 137
           W  WS CS +CG G+  +SRE    +   +G+ C           T+ C +NE      +
Sbjct: 507 WITWSPCSISCGMGM--RSRERYVKQFPEDGSVC-----TLPTEETEKCTVNE------E 553

Query: 138 CSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEMLGGFVADGTPCRQAIGSRD 197
           CS  + +      + EW  + +    C +    R      M+    ADG+ C+      +
Sbjct: 554 CSPSSCL------MTEWGEWDEYSATCGMGMKKRH----RMIKMNPADGSMCKAETSQAE 603

Query: 198 MCISGVCYKVGCDWIVDSDVEEDACGVCGGDG 229
             +   C+ + C  ++    E   C V  G G
Sbjct: 604 KRMMPECHTIPC--LLSPWSEWSDCSVTCGKG 633


>AB051390-1|BAB18461.1|  807|Homo sapiens VSGP/F-spondin protein.
          Length = 807

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           PWSEWS+CS TCG G+ T+ R   +   + +   C  D  + + C    CPI+
Sbjct: 619 PWSEWSDCSVTCGKGMRTRQRMLKSLAELGD---CNEDLEQVEKCMLPECPID 668



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 1/50 (2%)

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           PW+ WSEC++ CG G+  +          +    C  D+   + CN  PC
Sbjct: 759 PWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSC-KDKKEIRACNVHPC 807



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 7/83 (8%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC----PINEPSF 133
           WS+WSEC+++CG G   ++R     EP   G  C  +  + K C    C     I +P +
Sbjct: 674 WSQWSECNKSCGKGHVIRTRMI-QMEPQFGGAPC-PETVQRKKCRIRKCLRNPSIQKPRW 731

Query: 134 REVQCSRHNNMPYKNETIDEWVP 156
           RE + SR +    K E+  E  P
Sbjct: 732 REARESRRSEQ-LKEESEGEQFP 753



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 4/50 (8%)

Query: 78  WSEWSECSRTCGAGVSTQSRECN-NPEPVNNGNYCIGDRSRYKVCNTDPC 126
           W EW ECS TCG G+  + R    NP    +G+ C  + S+ + C    C
Sbjct: 564 WGEWDECSATCGMGMKKRHRMIKMNPA---DGSMCKAETSQAEKCMMPEC 610



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 3/68 (4%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGA 421
           EW  CS TCG+G  +R +  I  +    + S C        + +M +C    C+      
Sbjct: 566 EWDECSATCGMGMKKR-HRMIKMNP--ADGSMCKAETSQAEKCMMPECHTIPCLLSPWSE 622

Query: 422 WNPCSKLC 429
           W+ CS  C
Sbjct: 623 WSDCSVTC 630



 Score = 35.9 bits (79), Expect = 0.31
 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC-YHIEPPRHQALMKQCRKPACVHWWVGA 421
           W+PCS++CG+G   R    + Q     + S C    E      + ++C   +C+    G 
Sbjct: 510 WSPCSISCGMGMRSR-ERYVKQFPE--DGSVCTLPTEEMEKCTVNEECSPSSCLMTEWGE 566

Query: 422 WNPCSKLCHM 431
           W+ CS  C M
Sbjct: 567 WDECSATCGM 576



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           SEW+ CSVTCG G   R        + + E   C        + ++ +C     +  W  
Sbjct: 621 SEWSDCSVTCGKGMRTRQ----RMLKSLAELGDCNEDLEQVEKCMLPECPIDCELTEW-S 675

Query: 421 AWNPCSKLC 429
            W+ C+K C
Sbjct: 676 QWSECNKSC 684


>AB018305-1|BAA34482.2|  724|Homo sapiens KIAA0762 protein protein.
          Length = 724

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           PWSEWS+CS TCG G+ T+ R   +   + +   C  D  + + C    CPI+
Sbjct: 536 PWSEWSDCSVTCGKGMRTRQRMLKSLAELGD---CNEDLEQVEKCMLPECPID 585



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 1/50 (2%)

Query: 77  PWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           PW+ WSEC++ CG G+  +          +    C  D+   + CN  PC
Sbjct: 676 PWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSC-KDKKEIRACNVHPC 724



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 4/50 (8%)

Query: 78  WSEWSECSRTCGAGVSTQSRECN-NPEPVNNGNYCIGDRSRYKVCNTDPC 126
           W EW ECS TCG G+  + R    NP    +G+ C  + S+ + C    C
Sbjct: 481 WGEWDECSATCGMGMKKRHRMIKMNPA---DGSMCKAETSQAEKCMMPEC 527



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQC-YHIEPPRHQALMKQCRKPACVHWWVGA 421
           W+PCS++CG+G   R    + Q     + S C    E      + ++C   +C+    G 
Sbjct: 427 WSPCSISCGMGMRSR-ERYVKQFPE--DGSVCTLPTEETEKCTVNEECSPSSCLMTEWGE 483

Query: 422 WNPCSKLCHM 431
           W+ CS  C M
Sbjct: 484 WDECSATCGM 493



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 3/68 (4%)

Query: 362 EWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGA 421
           EW  CS TCG+G  +R +  I  +    + S C        + +M +C    C+      
Sbjct: 483 EWDECSATCGMGMKKR-HRMIKMNP--ADGSMCKAETSQAEKCMMPECHTIPCLLSPWSE 539

Query: 422 WNPCSKLC 429
           W+ CS  C
Sbjct: 540 WSDCSVTC 547



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 3/60 (5%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQ 137
           WS+WSEC+++CG G   ++R     EP   G  C  +  + K C    C +  PS ++++
Sbjct: 591 WSQWSECNKSCGKGHVIRTRMI-QMEPQFGGAPC-PETVQRKKCRIRKC-LRNPSIQKLR 647



 Score = 35.1 bits (77), Expect = 0.54
 Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 25/152 (16%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSFREVQ 137
           W  WS CS +CG G+  +SRE    +   +G+ C           T+ C +NE      +
Sbjct: 424 WITWSPCSISCGMGM--RSRERYVKQFPEDGSVC-----TLPTEETEKCTVNE------E 470

Query: 138 CSRHNNMPYKNETIDEWVPYFDQDKPCELQCVPRDGTDVEMLGGFVADGTPCRQAIGSRD 197
           CS  + +      + EW  + +    C +    R      M+    ADG+ C+      +
Sbjct: 471 CSPSSCL------MTEWGEWDECSATCGMGMKKRH----RMIKMNPADGSMCKAETSQAE 520

Query: 198 MCISGVCYKVGCDWIVDSDVEEDACGVCGGDG 229
            C+   C+ + C  ++    E   C V  G G
Sbjct: 521 KCMMPECHTIPC--LLSPWSEWSDCSVTCGKG 550



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVG 420
           SEW+ CSVTCG G   R        + + E   C        + ++ +C     +  W  
Sbjct: 538 SEWSDCSVTCGKGMRTRQ----RMLKSLAELGDCNEDLEQVEKCMLPECPIDCELTEW-S 592

Query: 421 AWNPCSKLC 429
            W+ C+K C
Sbjct: 593 QWSECNKSC 601


>AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein.
          Length = 1023

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 5/73 (6%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VH 416
           + +  W PCS TCGVG   R   C+   +      +C   +P   QA    C +  C   
Sbjct: 39  WHVGSWGPCSATCGVGIQTRDVYCLHPGETPAPPEECRDEKPHALQA----CNQFDCPPG 94

Query: 417 WWVGAWNPCSKLC 429
           W +  W  CS+ C
Sbjct: 95  WHIEEWQQCSRTC 107



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 11/117 (9%)

Query: 363 WTPCSVTCG-VGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVG 420
           W+ CS TCG +G   +  +C+  + + V ++ C H++ P   A  + C    C   W+  
Sbjct: 765 WSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHLQKP--LAGFEPCNIRDCPARWFTS 822

Query: 421 AWNPCSKLCHMPGEEVTKERSVYCVDKVMN---KVVDDSECGQVIKPITTIKCADVP 474
            W+ CS  C   GE     R V C     N   +VV    C    +P+    C   P
Sbjct: 823 VWSQCSVSC---GEGY-HSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPCFGHP 875



 Score = 38.7 bits (86), Expect = 0.044
 Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 6/94 (6%)

Query: 384 QHQRVVEQSQCYHIEPPRHQALMKQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSV 442
           +H      S   + +  +   L + C   AC V W  G W PC+  C   G    + R V
Sbjct: 899 RHTACQHNSSDSNCDDRKRPTLRRNCTSGACDVCWHTGPWKPCTAAC---GRGF-QSRKV 954

Query: 443 YCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
            C+     K V    C Q  KPI+   C   P+C
Sbjct: 955 DCIHTRSCKPVAKRHCVQKKKPISWRHCLG-PSC 987



 Score = 37.5 bits (83), Expect = 0.10
 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 7/63 (11%)

Query: 384 QHQRVVEQSQCYHIEPPRHQALMKQCRKPACV-HWWVGAWNPCSKLCHMPGEEVTKERSV 442
           Q Q+ V  S C  +  P   A+ + C    C   W VG+W PCS  C +      + R V
Sbjct: 7   QTQQTVNDSLCDMVHRP--PAMSQACNTEPCPPRWHVGSWGPCSATCGVG----IQTRDV 60

Query: 443 YCV 445
           YC+
Sbjct: 61  YCL 63



 Score = 37.1 bits (82), Expect = 0.13
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 8/85 (9%)

Query: 58  NQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNP-EPVNNGNYCIGDRS 116
           +Q C      P    G WGP      CS TCG G+ T+   C +P E       C  ++ 
Sbjct: 27  SQACNTEPCPPRWHVGSWGP------CSATCGVGIQTRDVYCLHPGETPAPPEECRDEKP 80

Query: 117 R-YKVCNTDPCPINEPSFREVQCSR 140
              + CN   CP         QCSR
Sbjct: 81  HALQACNQFDCPPGWHIEEWQQCSR 105



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 12/91 (13%)

Query: 46  PGTTCGPDMWCQNQTCVA-RTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEP 104
           PG T  P   C+++   A +  +      GW    EW +CSRTCG G  TQ+R     + 
Sbjct: 65  PGETPAPPEECRDEKPHALQACNQFDCPPGWHI-EEWQQCSRTCGGG--TQNRRVTCRQL 121

Query: 105 VNNGNY-------CIGDR-SRYKVCNTDPCP 127
           + +G++       C G + S +K C    CP
Sbjct: 122 LTDGSFLNLSDELCQGPKASSHKSCARTDCP 152



 Score = 35.5 bits (78), Expect = 0.41
 Identities = 30/111 (27%), Positives = 41/111 (36%), Gaps = 4/111 (3%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQAL-MKQCRKPACVHWWV 419
           S W+ CSV+CG GY  R   C         Q        P+ + L  K C    CV W  
Sbjct: 822 SVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPCFGHPCVQWEP 881

Query: 420 GAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
           G  N C   C M      ++R   C     +   DD +   + +  T+  C
Sbjct: 882 G--NRCPGRC-MGRAVRMQQRHTACQHNSSDSNCDDRKRPTLRRNCTSGAC 929



 Score = 34.7 bits (76), Expect = 0.72
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 6/80 (7%)

Query: 65  TPSPAPRDGGWGPWSEWSECSRTCG-AGVSTQSREC--NNPEPVNNG--NYCIGDRSRYK 119
           T  P P++  W P   WS CS TCG  G   Q  +C   N + V+    ++     + ++
Sbjct: 750 TGEPPPQEPFWEP-GNWSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHLQKPLAGFE 808

Query: 120 VCNTDPCPINEPSFREVQCS 139
            CN   CP    +    QCS
Sbjct: 809 PCNIRDCPARWFTSVWSQCS 828



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 9/77 (11%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC----IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           + + EW  CS TCG G   R   C     D     +    C   +   H    K C +  
Sbjct: 95  WHIEEWQQCSRTCGGGTQNRRVTCRQLLTDGSFLNLSDELCQGPKASSH----KSCARTD 150

Query: 414 C-VHWWVGAWNPCSKLC 429
           C  H  VG W+ CS  C
Sbjct: 151 CPPHLAVGDWSKCSVSC 167



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 2/52 (3%)

Query: 363 WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           W PC+  CG G+  R  +CI  H R  +     H    +     + C  P+C
Sbjct: 938 WKPCTAACGRGFQSRKVDCI--HTRSCKPVAKRHCVQKKKPISWRHCLGPSC 987



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 360 LSEWTPCSVTCGVGYTRRYYEC--IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           + +W+ CSV+CGVG  RR   C  +    R +  S+    + P    L++ C+ P C
Sbjct: 157 VGDWSKCSVSCGVGIQRRKQVCQRLAAKGRRIPLSEMMCRDLP-GLPLVRSCQMPEC 212


>M25631-1|AAA36741.1|  397|Homo sapiens thrombospondin protein.
          Length = 397

 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 1/59 (1%)

Query: 31  CLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCG 89
           C   N  T   + + P   C        + C    PS +  D GW PWSEW+ CS +CG
Sbjct: 339 CHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSA-DDGWSPWSEWTSCSTSCG 396


>AY358149-1|AAQ88516.1|  429|Homo sapiens THSD1 protein.
          Length = 429

 Score = 44.4 bits (100), Expect = 9e-04
 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 2/52 (3%)

Query: 75  WGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
           WG W  WS+CS TCG GV  + R C    P  +   C G      +C+ + C
Sbjct: 343 WGLWQPWSQCSATCGDGVRERRRVCLTSFP--SSPVCPGMSLEASLCSLEEC 392


>AF542080-1|AAN17826.1| 1156|Homo sapiens cartilage intermediate
           layer protein-like protein CLIP-2 protein.
          Length = 1156

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 70  PRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCP 127
           P +  WG W  W  CS +CG G   + R C +P     G+ C G     + C    CP
Sbjct: 144 PLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPA----GDACPGRPLEAQKCVRPRCP 197


>BC100790-1|AAI00791.1|  284|Homo sapiens C9orf94 protein protein.
          Length = 284

 Score = 41.9 bits (94), Expect = 0.005
 Identities = 25/117 (21%), Positives = 46/117 (39%), Gaps = 8/117 (6%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC----IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           + ++ W+ C+ +CG G   R   C           V    C  +   +     + C +  
Sbjct: 71  WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVA--KRPVDTQACNQQL 128

Query: 414 CVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
           CV W   +W  C+  C  P   V + R V+C  +     +   +C  + +P++T  C
Sbjct: 129 CVEWAFSSWGQCNGPCIGPHLAV-QHRQVFCQTR-DGITLPSEQCSALPRPVSTQNC 183



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 10/121 (8%)

Query: 358 YRLSEWTPCSVTC---GVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           +  S W  C+  C    +    R   C  +    +   QC  +  P      + C   AC
Sbjct: 132 WAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRP---VSTQNCWSEAC 188

Query: 415 -VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADV 473
            VHW V  W  C+  C   G    + R V CV    NK V +  C    +P    +C   
Sbjct: 189 SVHWRVSLWTLCTATC---GNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNIT 245

Query: 474 P 474
           P
Sbjct: 246 P 246


>BC100788-1|AAI00789.1|  467|Homo sapiens C9orf94 protein protein.
          Length = 467

 Score = 41.9 bits (94), Expect = 0.005
 Identities = 25/117 (21%), Positives = 46/117 (39%), Gaps = 8/117 (6%)

Query: 358 YRLSEWTPCSVTCGVGYTRRYYEC----IDQHQRVVEQSQCYHIEPPRHQALMKQCRKPA 413
           + ++ W+ C+ +CG G   R   C           V    C  +   +     + C +  
Sbjct: 254 WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVA--KRPVDTQACNQQL 311

Query: 414 CVHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKC 470
           CV W   +W  C+  C  P   V + R V+C  +     +   +C  + +P++T  C
Sbjct: 312 CVEWAFSSWGQCNGPCIGPHLAV-QHRQVFCQTR-DGITLPSEQCSALPRPVSTQNC 366



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 10/121 (8%)

Query: 358 YRLSEWTPCSVTC---GVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPAC 414
           +  S W  C+  C    +    R   C  +    +   QC  +  P      + C   AC
Sbjct: 315 WAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRP---VSTQNCWSEAC 371

Query: 415 -VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADV 473
            VHW V  W  C+  C   G    + R V CV    NK V +  C    +P    +C   
Sbjct: 372 SVHWRVSLWTLCTATC---GNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNIT 428

Query: 474 P 474
           P
Sbjct: 429 P 429


>AB051466-1|BAB21770.1| 1536|Homo sapiens KIAA1679 protein protein.
          Length = 1536

 Score = 41.9 bits (94), Expect = 0.005
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 9/80 (11%)

Query: 358  YRLSEWTPCSVT----CGVGYTRRYYECIDQHQRVVEQSQC--YHIEPPRHQAL--MKQC 409
            Y L+EW+ C ++    CG G   R   C+    + V   QC  +++E P+  ++  + +C
Sbjct: 1115 YNLTEWSTCQLSENAPCGQGVRTRLLSCVCSDGKPVSMDQCEQHNLEKPQRMSIPCLVEC 1174

Query: 410  RKPACVHWWVGAWNPCSKLC 429
                 +  W  AW  CS+ C
Sbjct: 1175 VVNCQLSGWT-AWTECSQTC 1193



 Score = 39.9 bits (89), Expect = 0.019
 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 9/87 (10%)

Query: 42  RPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNN 101
           RP  P + C    + Q + CV     P P D     WS W  CS +CG GV  +S+    
Sbjct: 904 RPVDP-SFCSSSGYIQEK-CVI----PCPFDCKLSDWSSWGSCSSSCGIGVRIRSKWLKE 957

Query: 102 PEPVNNGNYC--IGDRSRYKVCNTDPC 126
            +P N G  C  +  +++ +V    PC
Sbjct: 958 -KPYNGGRPCPKLDLKNQAQVHEAVPC 983



 Score = 39.1 bits (87), Expect = 0.033
 Identities = 27/109 (24%), Positives = 39/109 (35%), Gaps = 7/109 (6%)

Query: 369 TCGVGYTRRYYECIDQHQRVVEQSQC-YHIEPPRHQALMKQCRKPACVHWWVGAWNPCSK 427
           TCGVG   R   C+  H   V   +C     P   +     C+K  C+      W PC +
Sbjct: 621 TCGVGIQTRRVFCVKSHVGQVMTKRCPDSTRPETVRPCFLPCKKD-CIVTAFSEWTPCPR 679

Query: 428 LCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
           +C      V + R    + +  N      EC   +      +C DV  C
Sbjct: 680 MCQAGNATVKQSRYRIIIQEAAN---GGQECPDTL--YEERECEDVSLC 723



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 78   WSEWSECSRTCG-AGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC 126
            W+ W+ECS+TCG  G  +++R    P     G  C  + ++ K C   PC
Sbjct: 1183 WTAWTECSQTCGHGGRMSRTRFIIMPTQ-GEGRPCPTELTQEKTCPVTPC 1231



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 3/67 (4%)

Query: 68  PAPRDGGWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTD-PC 126
           P PRD     +  WS CS+ CG  +  ++R    P P+  G  C  + +  + C+    C
Sbjct: 103 PCPRDCVVSEFLPWSNCSKGCGKKLQHRTRAVIAP-PLFGGLQC-PNLTESRACDAPISC 160

Query: 127 PINEPSF 133
           P+ E  +
Sbjct: 161 PLGEEEY 167



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 11/22 (50%), Positives = 14/22 (63%)

Query: 70  PRDGGWGPWSEWSECSRTCGAG 91
           P+D     WS WS CS+TC +G
Sbjct: 262 PKDCETSQWSSWSPCSKTCRSG 283



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 2/82 (2%)

Query: 15   EAGLCSKLSELCEHLWCLVDNVCTTMMRPAAPGTTCGPDMWCQNQTCVARTPSPAPRDGG 74
            E G C +  ++   L C+V +   +          CG +M  Q+         P P D  
Sbjct: 1245 EGGDCGEGVQI-RSLSCMVHSGSISHAAGRVEDALCG-EMPFQDSILKQLCSVPCPGDCH 1302

Query: 75   WGPWSEWSECSRTCGAGVSTQS 96
               WSEWS C  TC  G S ++
Sbjct: 1303 LTEWSEWSTCELTCIDGRSFET 1324



 Score = 31.5 bits (68), Expect = 6.7
 Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 1/72 (1%)

Query: 370 CGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLC 429
           CG+G+      C +     V  S C    PP  ++    CR    +  W   W+ CS+ C
Sbjct: 487 CGLGHRILKAVCQNDRGEDVSGSLCPVPPPPERKSCEIPCRMDCVLSEWT-EWSSCSQSC 545

Query: 430 HMPGEEVTKERS 441
                +  + RS
Sbjct: 546 SNKNSDGKQTRS 557



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 9/80 (11%)

Query: 364 TPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAWN 423
           T  S  CG G   R   CI    R  E  +C   +      L+++C  P        AW+
Sbjct: 748 TGSSEACGKGLQTRAVSCISDDNRSAEMMECLK-QTNGMPLLVQECTVPCREDCTFTAWS 806

Query: 424 ---PCSKLCHMPGEEVTKER 440
              PCS  C     E TK R
Sbjct: 807 KFTPCSTNC-----EATKSR 821



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 12/104 (11%)

Query: 363  WTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAW 422
            WT CS TCG G        + + + ++  +Q      P      K C    C  W +G W
Sbjct: 1186 WTECSQTCGHGGR------MSRTRFIIMPTQGEGRPCPTELTQEKTCPVTPCYSWVLGNW 1239

Query: 423  NPCSKLCHMPGEEVTKERSVYCV---DKVMNKV--VDDSECGQV 461
            + C       GE V + RS+ C+     + +    V+D+ CG++
Sbjct: 1240 SACKLEGGDCGEGV-QIRSLSCMVHSGSISHAAGRVEDALCGEM 1282


>J04506-1|AAB59433.1|  491|Homo sapiens complement component C6
           protein.
          Length = 491

 Score = 41.1 bits (92), Expect = 0.008
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 3/54 (5%)

Query: 78  WSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYC--IGDRSRYKVCNTDPCPIN 129
           W++W+ CS+TC +G  ++ R+    +     N+C  I  +   + CN   CPIN
Sbjct: 29  WTQWTSCSKTCNSGTQSRHRQI-VVDKYYQENFCEQICSKQETRECNWQRCPIN 81


>BC035776-1|AAH35776.1| 1184|Homo sapiens cartilage intermediate
           layer protein, nucleotide pyrophosphohydrolase protein.
          Length = 1184

 Score = 41.1 bits (92), Expect = 0.008
 Identities = 15/26 (57%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 75  WGPWSEWSECSRTCG-AGVSTQSREC 99
           W PWS WS+CS  CG  GV T++R C
Sbjct: 152 WSPWSPWSKCSAACGQTGVQTRTRIC 177


>AY358904-1|AAQ89263.1| 1184|Homo sapiens CILP protein.
          Length = 1184

 Score = 41.1 bits (92), Expect = 0.008
 Identities = 15/26 (57%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 75  WGPWSEWSECSRTCG-AGVSTQSREC 99
           W PWS WS+CS  CG  GV T++R C
Sbjct: 152 WSPWSPWSKCSAACGQTGVQTRTRIC 177


>AF035455-1|AAF14689.1| 1184|Homo sapiens cartilage intermediate
           layer protein protein.
          Length = 1184

 Score = 41.1 bits (92), Expect = 0.008
 Identities = 15/26 (57%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 75  WGPWSEWSECSRTCG-AGVSTQSREC 99
           W PWS WS+CS  CG  GV T++R C
Sbjct: 152 WSPWSPWSKCSAACGQTGVQTRTRIC 177


>AF035408-1|AAC33838.1| 1184|Homo sapiens cartilage intermediate
           layer protein protein.
          Length = 1184

 Score = 41.1 bits (92), Expect = 0.008
 Identities = 15/26 (57%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 75  WGPWSEWSECSRTCG-AGVSTQSREC 99
           W PWS WS+CS  CG  GV T++R C
Sbjct: 152 WSPWSPWSKCSAACGQTGVQTRTRIC 177


>AB022430-1|BAA76692.1| 1184|Homo sapiens cartilage intermediate
           layer protein protein.
          Length = 1184

 Score = 41.1 bits (92), Expect = 0.008
 Identities = 15/26 (57%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 75  WGPWSEWSECSRTCG-AGVSTQSREC 99
           W PWS WS+CS  CG  GV T++R C
Sbjct: 152 WSPWSPWSKCSAACGQTGVQTRTRIC 177


>AL133463-1|CAC16127.3|  418|Homo sapiens chromosome 20 open reading
           frame 82 protein.
          Length = 418

 Score = 40.3 bits (90), Expect = 0.014
 Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 10/61 (16%)

Query: 74  GWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSF 133
           G G WS WS CS TCG G   ++R C        G  C    SR   C+   CP  E +F
Sbjct: 173 GEGDWSLWSVCSVTCGNGNQKRTRSC--------GYACTATESR--TCDRPNCPGIEDTF 222

Query: 134 R 134
           R
Sbjct: 223 R 223


>AL050320-3|CAC36074.2|  418|Homo sapiens chromosome 20 open reading
           frame 82 protein.
          Length = 418

 Score = 40.3 bits (90), Expect = 0.014
 Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 10/61 (16%)

Query: 74  GWGPWSEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPINEPSF 133
           G G WS WS CS TCG G   ++R C        G  C    SR   C+   CP  E +F
Sbjct: 173 GEGDWSLWSVCSVTCGNGNQKRTRSC--------GYACTATESR--TCDRPNCPGIEDTF 222

Query: 134 R 134
           R
Sbjct: 223 R 223


>AF005664-1|AAB63279.1|  160|Homo sapiens properdin protein.
          Length = 160

 Score = 39.9 bits (89), Expect = 0.019
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 361 SEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHW--W 418
           S W PCSVTC  G   RY  C+  + +   +     +E        +QC  P    W  W
Sbjct: 84  STWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC-CPEMGGWSGW 142

Query: 419 VGAWNPCSKLC 429
            G W PCS  C
Sbjct: 143 -GPWEPCSVTC 152



 Score = 39.5 bits (88), Expect = 0.025
 Identities = 19/51 (37%), Positives = 22/51 (43%), Gaps = 7/51 (13%)

Query: 45  APGTTCGPDMWCQNQTCVARTPSPAPRDGGWGPWSEWSECSRTCGAGVSTQ 95
           APGT       C++Q C        P  GGW  W  W  CS TC  G  T+
Sbjct: 116 APGTLEWQLQACEDQQC-------CPEMGGWSGWGPWEPCSVTCSKGTRTR 159



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 3/34 (8%)

Query: 66  PSPAPRDGGWGPWSEWSECSRTCGAGVSTQSREC 99
           P  +PR   W  WS W+ CS TC  G   + R C
Sbjct: 74  PCRSPR---WSLWSTWAPCSVTCSEGSQLRYRRC 104


>BC033125-1|AAH33125.1|  740|Homo sapiens THSD7B protein protein.
          Length = 740

 Score = 39.1 bits (87), Expect = 0.033
 Identities = 27/109 (24%), Positives = 39/109 (35%), Gaps = 7/109 (6%)

Query: 369 TCGVGYTRRYYECIDQHQRVVEQSQC-YHIEPPRHQALMKQCRKPACVHWWVGAWNPCSK 427
           TCGVG   R   C+  H   V   +C     P   +     C+K  C+      W PC +
Sbjct: 440 TCGVGIQTRRVFCVKSHVGQVMTKRCPDSTRPETVRPCFLPCKKD-CIVTAFSEWTPCPR 498

Query: 428 LCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
           +C      V + R    + +  N      EC   +      +C DV  C
Sbjct: 499 MCQAGNATVKQSRYRIIIQEAAN---GGQECPDTL--YEERECEDVSLC 542



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 11/22 (50%), Positives = 14/22 (63%)

Query: 70  PRDGGWGPWSEWSECSRTCGAG 91
           P+D     WS WS CS+TC +G
Sbjct: 81  PKDCETSQWSSWSPCSKTCRSG 102



 Score = 31.5 bits (68), Expect = 6.7
 Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 1/72 (1%)

Query: 370 CGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLC 429
           CG+G+      C +     V  S C    PP  ++    CR    +  W   W+ CS+ C
Sbjct: 306 CGLGHRILKAVCQNDRGEDVSGSLCPVPPPPERKSCEIPCRMDCVLSEWT-EWSSCSQSC 364

Query: 430 HMPGEEVTKERS 441
                +  + RS
Sbjct: 365 SNKNSDGKQTRS 376



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 9/80 (11%)

Query: 364 TPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAWN 423
           T  S  CG G   R   CI    R  E  +C   +      L+++C  P        AW+
Sbjct: 567 TGSSEACGKGLQTRAVSCISDDNRSAEMMECLK-QTNGMPLLVQECTVPCREDCTFTAWS 625

Query: 424 ---PCSKLCHMPGEEVTKER 440
              PCS  C     E TK R
Sbjct: 626 KFTPCSTNC-----EATKSR 640


>BC019344-1|AAH19344.1|  740|Homo sapiens THSD7B protein protein.
          Length = 740

 Score = 39.1 bits (87), Expect = 0.033
 Identities = 27/109 (24%), Positives = 39/109 (35%), Gaps = 7/109 (6%)

Query: 369 TCGVGYTRRYYECIDQHQRVVEQSQC-YHIEPPRHQALMKQCRKPACVHWWVGAWNPCSK 427
           TCGVG   R   C+  H   V   +C     P   +     C+K  C+      W PC +
Sbjct: 440 TCGVGIQTRRVFCVKSHVGQVMTKRCPDSTRPETVRPCFLPCKKD-CIVTAFSEWTPCPR 498

Query: 428 LCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPITTIKCADVPAC 476
           +C      V + R    + +  N      EC   +      +C DV  C
Sbjct: 499 MCQAGNATVKQSRYRIIIQEAAN---GGQECPDTL--YEERECEDVSLC 542



 Score = 32.3 bits (70), Expect = 3.8
 Identities = 11/22 (50%), Positives = 14/22 (63%)

Query: 70  PRDGGWGPWSEWSECSRTCGAG 91
           P+D     WS WS CS+TC +G
Sbjct: 81  PKDCETSQWSSWSPCSKTCRSG 102



 Score = 31.5 bits (68), Expect = 6.7
 Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 1/72 (1%)

Query: 370 CGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAWNPCSKLC 429
           CG+G+      C +     V  S C    PP  ++    CR    +  W   W+ CS+ C
Sbjct: 306 CGLGHRILKAVCQNDRGEDVSGSLCPVPPPPERKSCEIPCRMDCVLSEWT-EWSSCSQSC 364

Query: 430 HMPGEEVTKERS 441
                +  + RS
Sbjct: 365 SNKNSDGKQTRS 376



 Score = 31.1 bits (67), Expect = 8.9
 Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 9/80 (11%)

Query: 364 TPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEPPRHQALMKQCRKPACVHWWVGAWN 423
           T  S  CG G   R   CI    R  E  +C   +      L+++C  P        AW+
Sbjct: 567 TGSSEACGKGLQTRAVSCISDDNRSAEMMECLK-QTNGMPLLVQECTVPCREDCTFTAWS 625

Query: 424 ---PCSKLCHMPGEEVTKER 440
              PCS  C     E TK R
Sbjct: 626 KFTPCSTNC-----EATKSR 640


>AK128724-1|BAC87592.1|  160|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46891 fis, clone UTERU3018255. ).
          Length = 160

 Score = 37.5 bits (83), Expect = 0.10
 Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 407 KQCRKPAC-VHWWVGAWNPCSKLCHMPGEEVTKERSVYCVDKVMNKVVDDSECGQVIKPI 465
           + C   AC VHW V  W  C+  C   G    + R V CV    NK V +  C    +P 
Sbjct: 53  QNCWSEACSVHWRVSLWTLCTATC---GNYGFQSRRVECVHARTNKAVPEHLCSWGPRPA 109

Query: 466 TTIKCADVP 474
              +C   P
Sbjct: 110 NWQRCNITP 118


>Z98053-1|CAB10848.1|  381|Homo sapiens hCYR61 protein protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>Y12084-1|CAA72802.1|  381|Homo sapiens Gig1 protein protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>Y11307-1|CAA72167.1|  381|Homo sapiens CYR61 protein protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>U62015-1|AAB58319.1|  381|Homo sapiens Cyr61 protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>CR536519-1|CAG38757.1|  381|Homo sapiens CYR61 protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>BC016952-1|AAH16952.1|  381|Homo sapiens cysteine-rich, angiogenic
           inducer, 61 protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>BC009199-1|AAH09199.1|  381|Homo sapiens cysteine-rich, angiogenic
           inducer, 61 protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>BC001271-1|AAH01271.1|  381|Homo sapiens cysteine-rich, angiogenic
           inducer, 61 protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>AY443495-1|AAR05446.1|  381|Homo sapiens cysteine-rich, angiogenic
           inducer, 61 protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>AK223385-1|BAD97105.1|  381|Homo sapiens cysteine-rich, angiogenic
           inducer, 61 variant protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>AF307860-1|AAG59863.1|  381|Homo sapiens CYR61 protein protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>AF031385-1|AAB84227.1|  381|Homo sapiens Cyr61 protein protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>AF003594-1|AAB61240.1|  381|Homo sapiens growth-factor inducible
           immediate early gene product CYR61 protein.
          Length = 381

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 234 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 284

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 285 KCSKTKKSP 293


>AF003114-1|AAF21597.1|  334|Homo sapiens CYR61 protein.
          Length = 334

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 11/69 (15%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPC--PINEPSFREV 136
           + WS+CS+TCG G+ST+    +NPE       C   +   ++C   PC  P+     +  
Sbjct: 187 TSWSQCSKTCGTGISTRVTN-DNPE-------CRLVKET-RICEVRPCGQPVYSSLKKGK 237

Query: 137 QCSRHNNMP 145
           +CS+    P
Sbjct: 238 KCSKTKKSP 246


>Z99289-6|CAI42331.1|  354|Homo sapiens WNT1 inducible signaling
           pathway protein 3 protein.
          Length = 354

 Score = 34.3 bits (75), Expect = 0.95
 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 354 KKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEP 399
           KK   + ++WTPCS TCG+G + R        +   E+  CY I+P
Sbjct: 207 KKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCY-IQP 251



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 9/51 (17%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           ++W+ CSRTCG G+S +         V N N     R   ++C   PC  N
Sbjct: 214 TKWTPCSRTCGMGISNR---------VTNENSNCEMRKEKRLCYIQPCDSN 255


>Z99289-1|CAB16556.1|  331|Homo sapiens WNT1 inducible signaling
           pathway protein 3 protein.
          Length = 331

 Score = 34.3 bits (75), Expect = 0.95
 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 354 KKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEP 399
           KK   + ++WTPCS TCG+G + R        +   E+  CY I+P
Sbjct: 184 KKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCY-IQP 228



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 9/51 (17%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           ++W+ CSRTCG G+S +         V N N     R   ++C   PC  N
Sbjct: 191 TKWTPCSRTCGMGISNR---------VTNENSNCEMRKEKRLCYIQPCDSN 232


>BC105941-1|AAI05942.1|  372|Homo sapiens WNT1 inducible signaling
           pathway protein 3 protein.
          Length = 372

 Score = 34.3 bits (75), Expect = 0.95
 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 354 KKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEP 399
           KK   + ++WTPCS TCG+G + R        +   E+  CY I+P
Sbjct: 225 KKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCY-IQP 269



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 9/51 (17%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           ++W+ CSRTCG G+S +         V N N     R   ++C   PC  N
Sbjct: 232 TKWTPCSRTCGMGISNR---------VTNENSNCEMRKEKRLCYIQPCDSN 273


>AY358350-1|AAQ88716.1|  354|Homo sapiens WISP-3 protein.
          Length = 354

 Score = 34.3 bits (75), Expect = 0.95
 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 354 KKHSYRLSEWTPCSVTCGVGYTRRYYECIDQHQRVVEQSQCYHIEP 399
           KK   + ++WTPCS TCG+G + R        +   E+  CY I+P
Sbjct: 207 KKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCY-IQP 251



 Score = 32.7 bits (71), Expect = 2.9
 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 9/51 (17%)

Query: 79  SEWSECSRTCGAGVSTQSRECNNPEPVNNGNYCIGDRSRYKVCNTDPCPIN 129
           ++W+ CSRTCG G+S +         V N N     R   ++C   PC  N
Sbjct: 214 TKWTPCSRTCGMGISNR---------VTNENSNCEMRKEKRLCYIQPCDSN 255


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.320    0.135    0.458 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 83,170,861
Number of Sequences: 224733
Number of extensions: 3968427
Number of successful extensions: 10213
Number of sequences better than 10.0: 293
Number of HSP's better than 10.0 without gapping: 262
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 7280
Number of HSP's gapped (non-prelim): 1856
length of query: 476
length of database: 73,234,838
effective HSP length: 93
effective length of query: 383
effective length of database: 52,334,669
effective search space: 20044178227
effective search space used: 20044178227
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)

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