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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001434-TA|BGIBMGA001434-PA|undefined
         (110 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.     99   3e-21
AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and ...    99   3e-21
AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein.    95   4e-20
AF140675-1|AAD56358.1|  997|Homo sapiens zinc metalloprotease AD...    95   4e-20
AB209497-1|BAD92734.1|  527|Homo sapiens a disintegrin and metal...    95   4e-20
BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase w...    94   7e-20
BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase w...    72   4e-13
AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein.    72   4e-13
AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein.    72   4e-13
AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and ...    72   4e-13
AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.     72   4e-13
AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and ...    71   6e-13
AY692425-1|AAW47398.1|  468|Homo sapiens ADAMTS6 variant 3 protein.    70   1e-12
AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.    70   1e-12
AF140674-1|AAD56357.1|  860|Homo sapiens zinc metalloprotease AD...    70   1e-12
AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin metalloprot...    69   2e-12
BC036515-1|AAH36515.1|  967|Homo sapiens ADAM metallopeptidase w...    68   7e-12
AP001697-1|BAA95502.1|  967|Homo sapiens metalloprotease with th...    68   7e-12
AK129873-1|BAC85245.1|  226|Homo sapiens protein ( Homo sapiens ...    68   7e-12
AF207664-1|AAF23772.1|  967|Homo sapiens matrix metalloprotease ...    68   7e-12
AF170084-1|AAF15317.1|  967|Homo sapiens metalloproteinase with ...    68   7e-12
AF060152-1|AAD48080.1|  950|Homo sapiens METH1 protein protein.        68   7e-12
AB037767-1|BAA92584.1|  999|Homo sapiens KIAA1346 protein protein.     68   7e-12
DQ266047-1|ABB70405.1|  570|Homo sapiens ADAMTS16s alternative s...    66   3e-11
AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease disinte...    66   3e-11
AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.     66   3e-11
BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase w...    62   4e-10
BC113874-1|AAI13875.1|  676|Homo sapiens ADAMTS8 protein protein.      61   6e-10
BC089435-1|AAH89435.1|  918|Homo sapiens ADAMTS8 protein protein.      61   6e-10
AF175283-1|AAF25806.1|  246|Homo sapiens zinc metalloendopeptida...    61   6e-10
AF060153-1|AAD48081.1|  890|Homo sapiens METH2 protein protein.        61   6e-10
BC093777-1|AAH93777.1|  930|Homo sapiens ADAM metallopeptidase w...    61   8e-10
BC093775-1|AAH93775.1|  930|Homo sapiens ADAM metallopeptidase w...    61   8e-10
AP001698-1|BAA95504.1|  412|Homo sapiens disintegrin-like and me...    61   8e-10
AF142099-1|AAD49577.1|  930|Homo sapiens aggrecanase-2 protein.        61   8e-10
BC109114-1|AAI09115.1|  950|Homo sapiens ADAM metallopeptidase w...    60   1e-09
AJ315733-1|CAC86014.1|  950|Homo sapiens metalloprotease disinte...    60   1e-09
AY044847-1|AAL02262.1|  837|Homo sapiens aggrecanase 1 protein.        59   3e-09
AL590714-6|CAH72146.1|  837|Homo sapiens ADAM metallopeptidase w...    59   3e-09
AF148213-1|AAD41494.1|  837|Homo sapiens aggrecanase-1 protein.        59   3e-09
AB014588-1|BAA31663.2|  849|Homo sapiens KIAA0688 protein protein.     59   3e-09
AY358886-1|AAQ89245.1|  837|Homo sapiens ADAMTS4 protein.              58   4e-09
AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptida...    58   6e-09
BC063293-1|AAH63293.1|  837|Homo sapiens ADAM metallopeptidase w...    57   1e-08
DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase w...    54   9e-08
BC103829-1|AAI03830.1|  276|Homo sapiens ADAMTS13 protein protein.     54   9e-08
BC103828-1|AAI03829.1|  276|Homo sapiens ADAMTS13 protein protein.     54   9e-08
AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand factor-c...    54   9e-08
AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase ...    54   9e-08
AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase ...    54   9e-08
AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase w...    54   9e-08
AL158826-24|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase ...    54   9e-08
AL158826-23|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase ...    54   9e-08
AL158826-22|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase ...    54   9e-08
AJ420811-1|CAD12730.1|  344|Homo sapiens ADAMTS-13 protein, trun...    54   9e-08
AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, vari...    54   9e-08
AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.    54   9e-08
AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.             54   9e-08
AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand factor-c...    54   9e-08
BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.      53   2e-07
BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase w...    53   2e-07
AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.     53   2e-07
AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.             53   2e-07
BC030812-1|AAH30812.1|  339|Homo sapiens ADAMTS4 protein protein.      52   4e-07
AL590714-7|CAH72147.1|  339|Homo sapiens ADAM metallopeptidase w...    52   4e-07
AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-protein...    50   2e-06
AL358817-5|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase w...    49   4e-06
AL358817-4|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase w...    49   4e-06
AL355344-5|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase w...    49   4e-06
AL355344-4|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase w...    49   4e-06
AJ345098-1|CAC87943.1| 1223|Homo sapiens metalloprotease-disinte...    49   4e-06
AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.             49   4e-06
AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and ...    49   4e-06
AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.            48   6e-06
DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase w...    45   4e-05
AY532929-1|AAS54901.1|   90|Homo sapiens von Willebrand factor-c...    45   4e-05
AK131344-1|BAD18500.1|  502|Homo sapiens protein ( Homo sapiens ...    45   4e-05
AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disinte...    45   4e-05
AB209515-1|BAD92752.1|  847|Homo sapiens a disintegrin-like and ...    42   4e-04

>BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.
          Length = 1509

 Score = 98.7 bits (235), Expect = 3e-21
 Identities = 45/106 (42%), Positives = 65/106 (61%), Gaps = 2/106 (1%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M E+H  +++E Y+LTIMNMV+ L+ +PSIGN                         +A+
Sbjct: 258 MIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIVVVRLILLEEEEQGLKIVH--HAE 315

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
            TL+SFC+WQ+ +NP +D NP HHDVA+L+TR+DIC+  + PC  L
Sbjct: 316 KTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCETL 361


>AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and
           metalloprotease (reprolysin type) with thrombospondin ty
           protein.
          Length = 1593

 Score = 98.7 bits (235), Expect = 3e-21
 Identities = 45/106 (42%), Positives = 65/106 (61%), Gaps = 2/106 (1%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M E+H  +++E Y+LTIMNMV+ L+ +PSIGN                         +A+
Sbjct: 258 MIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIVVVRLILLEEEEQGLKIVH--HAE 315

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
            TL+SFC+WQ+ +NP +D NP HHDVA+L+TR+DIC+  + PC  L
Sbjct: 316 KTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCETL 361


>AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein.
          Length = 1686

 Score = 95.1 bits (226), Expect = 4e-20
 Identities = 45/106 (42%), Positives = 62/106 (58%), Gaps = 2/106 (1%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M E+H Q  +E Y+LTIMNMV+ L+ DPSIGN                       + +AD
Sbjct: 254 MVEYHGQPQVESYVLTIMNMVAGLFHDPSIGN--PIHITIVRLVLLEDEEEDLKITHHAD 311

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
           +TL SFC+WQ+ +N   D +P HHD AIL+TR+D+C+  + PC  L
Sbjct: 312 NTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETL 357


>AF140675-1|AAD56358.1|  997|Homo sapiens zinc metalloprotease
           ADAMTS7 protein.
          Length = 997

 Score = 95.1 bits (226), Expect = 4e-20
 Identities = 45/106 (42%), Positives = 62/106 (58%), Gaps = 2/106 (1%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M E+H Q  +E Y+LTIMNMV+ L+ DPSIGN                       + +AD
Sbjct: 254 MVEYHGQPQVESYVLTIMNMVAGLFHDPSIGN--PIHITIVRLVLLEDEEEDLKITHHAD 311

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
           +TL SFC+WQ+ +N   D +P HHD AIL+TR+D+C+  + PC  L
Sbjct: 312 NTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETL 357


>AB209497-1|BAD92734.1|  527|Homo sapiens a disintegrin and
           metalloprotease with thrombospondin motifs-7
           preproprotein va protein.
          Length = 527

 Score = 95.1 bits (226), Expect = 4e-20
 Identities = 45/106 (42%), Positives = 62/106 (58%), Gaps = 2/106 (1%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M E+H Q  +E Y+LTIMNMV+ L+ DPSIGN                       + +AD
Sbjct: 219 MVEYHGQPQVESYVLTIMNMVAGLFHDPSIGN--PIHITIVRLVLLEDEEEDLKITHHAD 276

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
           +TL SFC+WQ+ +N   D +P HHD AIL+TR+D+C+  + PC  L
Sbjct: 277 NTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETL 322


>BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 7 protein.
          Length = 1686

 Score = 94.3 bits (224), Expect = 7e-20
 Identities = 45/106 (42%), Positives = 61/106 (57%), Gaps = 2/106 (1%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M E+H Q  +E Y+LTIMNMV+ L+ DPSIGN                         +AD
Sbjct: 254 MVEYHGQPQVESYVLTIMNMVAGLFHDPSIGNPIHITIVRLVLLEDEEEDLKIMH--HAD 311

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
           +TL SFC+WQ+ +N   D +P HHD AIL+TR+D+C+  + PC  L
Sbjct: 312 NTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETL 357


>BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 9 protein.
          Length = 1935

 Score = 71.7 bits (168), Expect = 4e-13
 Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 6/110 (5%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M  +H ++ L+ Y+LT+M++V+S+Y DPSIGN                       S NA 
Sbjct: 305 MVSYHGEN-LQHYILTLMSIVASIYKDPSIGN--LINIVIVNLIVIHNEQDGPSISFNAQ 361

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLLLRNL 110
           +TL +FC+WQ   N        HHD A+L+TR+DIC  HD   +L L  L
Sbjct: 362 TTLKNFCQWQHSKNSPGGI---HHDTAVLLTRQDICRAHDKCDTLGLAEL 408


>AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein.
          Length = 1502

 Score = 71.7 bits (168), Expect = 4e-13
 Identities = 35/98 (35%), Positives = 56/98 (57%), Gaps = 3/98 (3%)

Query: 9   SLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASFCR 68
           +L+ Y+LT+M++V+++Y DPSIGN                       + +  +TL +FC 
Sbjct: 278 NLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEEGPVI--NFDGATTLKNFCS 335

Query: 69  WQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
           WQ+  N  +D +P HHD A+L+TR DICS  +  C++L
Sbjct: 336 WQQTQNDLDDVHPSHHDTAVLITRYDICSSKEK-CNML 372


>AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein.
          Length = 1908

 Score = 71.7 bits (168), Expect = 4e-13
 Identities = 35/98 (35%), Positives = 56/98 (57%), Gaps = 3/98 (3%)

Query: 9   SLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASFCR 68
           +L+ Y+LT+M++V+++Y DPSIGN                       + +  +TL +FC 
Sbjct: 278 NLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEEGPVI--NFDGATTLKNFCS 335

Query: 69  WQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
           WQ+  N  +D +P HHD A+L+TR DICS  +  C++L
Sbjct: 336 WQQTQNDLDDVHPSHHDTAVLITRYDICSSKEK-CNML 372


>AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and
           metalloprotease with thrombospondin type 1 motifs 9B
           protein.
          Length = 1935

 Score = 71.7 bits (168), Expect = 4e-13
 Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 6/110 (5%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M  +H ++ L+ Y+LT+M++V+S+Y DPSIGN                       S NA 
Sbjct: 305 MVSYHGEN-LQHYILTLMSIVASIYKDPSIGN--LINIVIVNLIVIHNEQDGPSISFNAQ 361

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLLLRNL 110
           +TL +FC+WQ   N        HHD A+L+TR+DIC  HD   +L L  L
Sbjct: 362 TTLKNFCQWQHSKNSPGGI---HHDTAVLLTRQDICRAHDKCDTLGLAEL 408


>AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.
          Length = 1471

 Score = 71.7 bits (168), Expect = 4e-13
 Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 6/110 (5%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M  +H ++ L+ Y+LT+M++V+S+Y DPSIGN                       S NA 
Sbjct: 147 MVSYHGEN-LQHYILTLMSIVASIYKDPSIGN--LINIVIVNLIVIHNEQDGPSISFNAQ 203

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLLLRNL 110
           +TL +FC+WQ   N        HHD A+L+TR+DIC  HD   +L L  L
Sbjct: 204 TTLKNFCQWQHSKNSPGGI---HHDTAVLLTRQDICRAHDKCDTLGLAEL 250


>AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and
           metalloprotease with thrombospondin type 1 motifs 20
           protein.
          Length = 1911

 Score = 71.3 bits (167), Expect = 6e-13
 Identities = 35/98 (35%), Positives = 55/98 (56%), Gaps = 3/98 (3%)

Query: 9   SLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASFCR 68
           +L+ Y+LT+M++V+++Y DPSIGN                       + +  +TL +FC 
Sbjct: 278 NLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEEGPVI--NFDGATTLKNFCS 335

Query: 69  WQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
           WQ+  N  +D +P HHD A+L+TR DICS  +  C+ L
Sbjct: 336 WQQTQNDLDDVHPSHHDTAVLITREDICSSKEK-CNTL 372


>AY692425-1|AAW47398.1|  468|Homo sapiens ADAMTS6 variant 3 protein.
          Length = 468

 Score = 70.1 bits (164), Expect = 1e-12
 Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 9/113 (7%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M  +H +  +E Y+L++MN+V+ LY D S+GN                       + +AD
Sbjct: 262 MVGYHGRKDIEHYILSVMNIVAKLYRDSSLGN--VVNIIVARLIVLTEDQPNLEINHHAD 319

Query: 61  STLASFCRWQEQL---NPDNDTNPH----HHDVAILVTRRDICSQHDSPCSLL 106
            +L SFC+WQ+ +     D +T P     HHD A+L+TR DIC+  + PC  L
Sbjct: 320 KSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTL 372


>AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.
          Length = 1117

 Score = 70.1 bits (164), Expect = 1e-12
 Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 9/113 (7%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M  +H +  +E Y+L++MN+V+ LY D S+GN                       + +AD
Sbjct: 262 MVGYHGRKDIEHYILSVMNIVAKLYRDSSLGN--VVNIIVARLIVLTEDQPNLEINHHAD 319

Query: 61  STLASFCRWQEQL---NPDNDTNPH----HHDVAILVTRRDICSQHDSPCSLL 106
            +L SFC+WQ+ +     D +T P     HHD A+L+TR DIC+  + PC  L
Sbjct: 320 KSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTL 372


>AF140674-1|AAD56357.1|  860|Homo sapiens zinc metalloprotease
           ADAMTS6 protein.
          Length = 860

 Score = 70.1 bits (164), Expect = 1e-12
 Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 9/113 (7%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M  +H +  +E Y+L++MN+V+ LY D S+GN                       + +AD
Sbjct: 262 MVGYHGRKDIEHYILSVMNIVAKLYRDSSLGN--VVNIIVARLIVLTEDQPNLEINHHAD 319

Query: 61  STLASFCRWQEQL---NPDNDTNPH----HHDVAILVTRRDICSQHDSPCSLL 106
            +L SFC+WQ+ +     D +T P     HHD A+L+TR DIC+  + PC  L
Sbjct: 320 KSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTL 372


>AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin
           metalloproteinase with thrombospondin repeats protein.
          Length = 1072

 Score = 69.3 bits (162), Expect = 2e-12
 Identities = 40/110 (36%), Positives = 57/110 (51%), Gaps = 6/110 (5%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M  +H ++ L+ Y+LT+M++V+S+Y DPSIGN                       S NA 
Sbjct: 305 MVSYHGEN-LQHYILTLMSIVASIYKDPSIGN--LINIVIVNLIVIHNEQDGPSISFNAQ 361

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLLLRNL 110
           +TL + C+WQ   N        HHD A+L+TR+DIC  HD   +L L  L
Sbjct: 362 TTLKNLCQWQHSKNSPGGI---HHDTAVLLTRQDICRAHDKCDTLGLAEL 408


>BC036515-1|AAH36515.1|  967|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 1 protein.
          Length = 967

 Score = 67.7 bits (158), Expect = 7e-12
 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+EFH    L+ YLLT+ ++ + LY  PSI N                       ++NA 
Sbjct: 270 MAEFHGS-GLKHYLLTLFSVAARLYKHPSIRN--SVSLVVVKILVIHDEQKGPEVTSNAA 326

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL +FC WQ+Q NP +D +  H+D AIL TR+D+C
Sbjct: 327 LTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLC 362


>AP001697-1|BAA95502.1|  967|Homo sapiens metalloprotease with
           thrombospondin type 1 motifs protein.
          Length = 967

 Score = 67.7 bits (158), Expect = 7e-12
 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+EFH    L+ YLLT+ ++ + LY  PSI N                       ++NA 
Sbjct: 270 MAEFHGS-GLKHYLLTLFSVAARLYKHPSIRN--SVSLVVVKILVIHDEQKGPEVTSNAA 326

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL +FC WQ+Q NP +D +  H+D AIL TR+D+C
Sbjct: 327 LTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLC 362


>AK129873-1|BAC85245.1|  226|Homo sapiens protein ( Homo sapiens
           cDNA FLJ26363 fis, clone HRT05360, highly similar to
           ADAM-TS 1 PRECURSOR (EC 3.4.24.-). ).
          Length = 226

 Score = 67.7 bits (158), Expect = 7e-12
 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+EFH    L+ YLLT+ ++ + LY  PSI N                       ++NA 
Sbjct: 32  MAEFHGS-GLKHYLLTLFSVAARLYKHPSIRN--SVSLVVVKILVIHDEQKGPEVTSNAA 88

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL +FC WQ+Q NP +D +  H+D AIL TR+D+C
Sbjct: 89  LTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLC 124


>AF207664-1|AAF23772.1|  967|Homo sapiens matrix metalloprotease
           protein.
          Length = 967

 Score = 67.7 bits (158), Expect = 7e-12
 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+EFH    L+ YLLT+ ++ + LY  PSI N                       ++NA 
Sbjct: 270 MAEFHGS-GLKHYLLTLFSVAARLYKHPSIRN--SVSLVVVKILVIHDEQKGPEVTSNAA 326

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL +FC WQ+Q NP +D +  H+D AIL TR+D+C
Sbjct: 327 LTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLC 362


>AF170084-1|AAF15317.1|  967|Homo sapiens metalloproteinase with
           thrombospondin type 1 motifs ADAMTS1 protein.
          Length = 967

 Score = 67.7 bits (158), Expect = 7e-12
 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+EFH    L+ YLLT+ ++ + LY  PSI N                       ++NA 
Sbjct: 270 MAEFHGS-GLKHYLLTLFSVAARLYKHPSIRN--SVSLVVVKILVIHDEQKGPEVTSNAA 326

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL +FC WQ+Q NP +D +  H+D AIL TR+D+C
Sbjct: 327 LTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLC 362


>AF060152-1|AAD48080.1|  950|Homo sapiens METH1 protein protein.
          Length = 950

 Score = 67.7 bits (158), Expect = 7e-12
 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+EFH    L+ YLLT+ ++ + LY  PSI N                       ++NA 
Sbjct: 253 MAEFHGS-GLKHYLLTLFSVAARLYKHPSIRN--SVSLVVVKILVIHDEQKGPEVTSNAA 309

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL +FC WQ+Q NP +D +  H+D AIL TR+D+C
Sbjct: 310 LTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLC 345


>AB037767-1|BAA92584.1|  999|Homo sapiens KIAA1346 protein protein.
          Length = 999

 Score = 67.7 bits (158), Expect = 7e-12
 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+EFH    L+ YLLT+ ++ + LY  PSI N                       ++NA 
Sbjct: 302 MAEFHGS-GLKHYLLTLFSVAARLYKHPSIRN--SVSLVVVKILVIHDEQKGPEVTSNAA 358

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL +FC WQ+Q NP +D +  H+D AIL TR+D+C
Sbjct: 359 LTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLC 394


>DQ266047-1|ABB70405.1|  570|Homo sapiens ADAMTS16s alternative
           splice form protein.
          Length = 570

 Score = 65.7 bits (153), Expect = 3e-11
 Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 5/106 (4%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M + H  +++  Y+LTI+NMVS+L+ D +IG                        S +AD
Sbjct: 302 MMQNHGHENITTYVLTILNMVSALFKDGTIGG--NINIAIVGLILLEDEQPGLVISHHAD 359

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
            TL+SFC+WQ  L   + T    HD AIL+T  DICS  + PC  L
Sbjct: 360 HTLSSFCQWQSGLMGKDGT---RHDHAILLTGLDICSWKNEPCDTL 402


>AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease
           disintegrin 16 with thrombospondin type I motif protein.
          Length = 1072

 Score = 65.7 bits (153), Expect = 3e-11
 Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 5/106 (4%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M + H  +++  Y+LTI+NMVS+L+ D +IG                        S +AD
Sbjct: 302 MMQNHGHENITTYVLTILNMVSALFKDGTIGG--NINIAIVGLILLEDEQPGLVISHHAD 359

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
            TL+SFC+WQ  L   + T    HD AIL+T  DICS  + PC  L
Sbjct: 360 HTLSSFCQWQSGLMGKDGT---RHDHAILLTGLDICSWKNEPCDTL 402


>AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.
          Length = 1021

 Score = 65.7 bits (153), Expect = 3e-11
 Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 5/106 (4%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M + H  +++  Y+LTI+NMVS+L+ D +IG                        S +AD
Sbjct: 99  MMQNHGHENITTYVLTILNMVSALFKDGTIGG--NINIAIVGLILLEDEQPGLVISHHAD 156

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
            TL+SFC+WQ  L   + T    HD AIL+T  DICS  + PC  L
Sbjct: 157 HTLSSFCQWQSGLMGKDGT---RHDHAILLTGLDICSWKNEPCDTL 199


>BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 18 protein.
          Length = 1221

 Score = 62.1 bits (144), Expect = 4e-10
 Identities = 38/106 (35%), Positives = 52/106 (49%), Gaps = 5/106 (4%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M E H + ++  Y+LT+MNMVS L+ D +IG+                       + +AD
Sbjct: 305 MVEKHGKGNVTTYILTVMNMVSGLFKDGTIGS--DINVVVVSLILLEQEPGGLLINHHAD 362

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
            +L SFC+WQ  L      N   HD AIL+T  DICS  + PC  L
Sbjct: 363 QSLNSFCQWQSAL---IGKNGKRHDHAILLTGFDICSWKNEPCDTL 405


>BC113874-1|AAI13875.1|  676|Homo sapiens ADAMTS8 protein protein.
          Length = 676

 Score = 61.3 bits (142), Expect = 6e-10
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 3/98 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ F+  D L+ ++LT+M++ + +Y  PSI N                       S N  
Sbjct: 18  MAAFYGAD-LQNHILTLMSVAARIYKHPSIKN--SINLMVVKVLIVEDEKWGPEVSDNGG 74

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQ 98
            TL +FC WQ + N  +D +P H+D AIL+TR++ C Q
Sbjct: 75  LTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQ 112


>BC089435-1|AAH89435.1|  918|Homo sapiens ADAMTS8 protein protein.
          Length = 918

 Score = 61.3 bits (142), Expect = 6e-10
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 3/98 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ F+  D L+ ++LT+M++ + +Y  PSI N                       S N  
Sbjct: 260 MAAFYGAD-LQNHILTLMSVAARIYKHPSIKN--SINLMVVKVLIVEDEKWGPEVSDNGG 316

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQ 98
            TL +FC WQ + N  +D +P H+D AIL+TR++ C Q
Sbjct: 317 LTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQ 354


>AF175283-1|AAF25806.1|  246|Homo sapiens zinc metalloendopeptidase
           protein.
          Length = 246

 Score = 61.3 bits (142), Expect = 6e-10
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 3/98 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ F+  D L+ ++LT+M++ + +Y  PSI N                       S N  
Sbjct: 38  MAAFYGAD-LQNHILTLMSVAARIYKHPSIKN--SINLMVVKVLIVEDEKWGPEVSDNGG 94

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQ 98
            TL +FC WQ + N  +D +P H+D AIL+TR++ C Q
Sbjct: 95  LTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQ 132


>AF060153-1|AAD48081.1|  890|Homo sapiens METH2 protein protein.
          Length = 890

 Score = 61.3 bits (142), Expect = 6e-10
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 3/98 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ F+  D L+ ++LT+M++ + +Y  PSI N                       S N  
Sbjct: 232 MAAFYGAD-LQNHILTLMSVAARIYKHPSIKN--SINLMVVKVLIVEDEKWGPEVSDNGG 288

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQ 98
            TL +FC WQ + N  +D +P H+D AIL+TR++ C Q
Sbjct: 289 LTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQ 326


>BC093777-1|AAH93777.1|  930|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
          Length = 930

 Score = 60.9 bits (141), Expect = 8e-10
 Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 10  LEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASFCRW 69
           L+ YLLT+ ++ + LY   SI N+                      S NA +TL +FC+W
Sbjct: 287 LQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEV--SKNAATTLKNFCKW 344

Query: 70  QEQLNPDNDTNPHHHDVAILVTRRDICSQH 99
           Q Q N   D +  H+D AIL TR D+C  H
Sbjct: 345 QHQHNQLGDDHEEHYDAAILFTREDLCGHH 374


>BC093775-1|AAH93775.1|  930|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
          Length = 930

 Score = 60.9 bits (141), Expect = 8e-10
 Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 10  LEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASFCRW 69
           L+ YLLT+ ++ + LY   SI N+                      S NA +TL +FC+W
Sbjct: 287 LQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEV--SKNAATTLKNFCKW 344

Query: 70  QEQLNPDNDTNPHHHDVAILVTRRDICSQH 99
           Q Q N   D +  H+D AIL TR D+C  H
Sbjct: 345 QHQHNQLGDDHEEHYDAAILFTREDLCGHH 374


>AP001698-1|BAA95504.1|  412|Homo sapiens disintegrin-like and
           metalloprotease with thrombospondin type 1 motif, 5
           protein.
          Length = 412

 Score = 60.9 bits (141), Expect = 8e-10
 Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 10  LEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASFCRW 69
           L+ YLLT+ ++ + LY   SI N+                      S NA +TL +FC+W
Sbjct: 287 LQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEV--SKNAATTLKNFCKW 344

Query: 70  QEQLNPDNDTNPHHHDVAILVTRRDICSQH 99
           Q Q N   D +  H+D AIL TR D+C  H
Sbjct: 345 QHQHNQLGDDHEEHYDAAILFTREDLCGHH 374


>AF142099-1|AAD49577.1|  930|Homo sapiens aggrecanase-2 protein.
          Length = 930

 Score = 60.9 bits (141), Expect = 8e-10
 Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 10  LEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASFCRW 69
           L+ YLLT+ ++ + LY   SI N+                      S NA +TL +FC+W
Sbjct: 287 LQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEV--SKNAATTLKNFCKW 344

Query: 70  QEQLNPDNDTNPHHHDVAILVTRRDICSQH 99
           Q Q N   D +  H+D AIL TR D+C  H
Sbjct: 345 QHQHNQLGDDHEEHYDAAILFTREDLCGHH 374


>BC109114-1|AAI09115.1|  950|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 15 protein.
          Length = 950

 Score = 60.5 bits (140), Expect = 1e-09
 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M +FH  D LE YLLT++   + LY  PSI N                       + NA 
Sbjct: 230 MVKFHGAD-LEHYLLTLLATAARLYRHPSILN--PINIVVVKVLLLRDRDSGPKVTGNAA 286

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL +FC WQ++LN  +D +P + D AIL TR+D+C
Sbjct: 287 LTLRNFCAWQKKLNKVSDKHPEYWDTAILFTRQDLC 322


>AJ315733-1|CAC86014.1|  950|Homo sapiens metalloprotease
           disintegrin 15 with thrombospondin domains protein.
          Length = 950

 Score = 60.5 bits (140), Expect = 1e-09
 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M +FH  D LE YLLT++   + LY  PSI N                       + NA 
Sbjct: 230 MVKFHGAD-LEHYLLTLLATAARLYRHPSILN--PINIVVVKVLLLRDRDSGPKVTGNAA 286

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL +FC WQ++LN  +D +P + D AIL TR+D+C
Sbjct: 287 LTLRNFCAWQKKLNKVSDKHPEYWDTAILFTRQDLC 322


>AY044847-1|AAL02262.1|  837|Homo sapiens aggrecanase 1 protein.
          Length = 837

 Score = 58.8 bits (136), Expect = 3e-09
 Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ FH    L+ YLLT+M   +  +  PSI N                       S  A 
Sbjct: 230 MAAFHGA-GLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPS--AA 286

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL SFC WQ  LN   D++P H D AIL TR+D+C
Sbjct: 287 QTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQDLC 322


>AL590714-6|CAH72146.1|  837|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 837

 Score = 58.8 bits (136), Expect = 3e-09
 Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ FH    L+ YLLT+M   +  +  PSI N                       S  A 
Sbjct: 230 MAAFHGA-GLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPS--AA 286

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL SFC WQ  LN   D++P H D AIL TR+D+C
Sbjct: 287 QTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQDLC 322


>AF148213-1|AAD41494.1|  837|Homo sapiens aggrecanase-1 protein.
          Length = 837

 Score = 58.8 bits (136), Expect = 3e-09
 Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ FH    L+ YLLT+M   +  +  PSI N                       S  A 
Sbjct: 230 MAAFHGA-GLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPS--AA 286

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL SFC WQ  LN   D++P H D AIL TR+D+C
Sbjct: 287 QTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQDLC 322


>AB014588-1|BAA31663.2|  849|Homo sapiens KIAA0688 protein protein.
          Length = 849

 Score = 58.8 bits (136), Expect = 3e-09
 Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ FH    L+ YLLT+M   +  +  PSI N                       S  A 
Sbjct: 242 MAAFHGA-GLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPS--AA 298

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL SFC WQ  LN   D++P H D AIL TR+D+C
Sbjct: 299 QTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQDLC 334


>AY358886-1|AAQ89245.1|  837|Homo sapiens ADAMTS4 protein.
          Length = 837

 Score = 58.4 bits (135), Expect = 4e-09
 Identities = 35/96 (36%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ FH    L+ YLLT+M   +  +  PSI N                       S  A 
Sbjct: 230 MAAFHGA-GLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPS--AA 286

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL SFC WQ  LN   D+ P H D AIL TR+D+C
Sbjct: 287 QTLRSFCAWQRGLNTPEDSGPDHFDTAILFTRQDLC 322


>AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptidase
           protein.
          Length = 1077

 Score = 58.0 bits (134), Expect = 6e-09
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 9/113 (7%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M  +H +  +E Y+L IMN+V+ L+ D S+G+                       + +A 
Sbjct: 225 MVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGS--TVNILVTRLILLTEDQPTLEITHHAG 282

Query: 61  STLASFCRWQEQL-------NPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
            +L SFC+WQ+ +       N   +    +HD A+L+TR DIC   + PC  L
Sbjct: 283 KSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTL 335


>BC063293-1|AAH63293.1|  837|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 837

 Score = 56.8 bits (131), Expect = 1e-08
 Identities = 34/96 (35%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ FH    L+ YLLT+M   +  +  PSI N                       S  A 
Sbjct: 230 MAAFHGA-GLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPS--AA 286

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDIC 96
            TL SFC WQ  LN   +++P H D AIL TR+D+C
Sbjct: 287 QTLRSFCAWQRGLNTPENSDPDHFDTAILFTRQDLC 322


>DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>BC103829-1|AAI03830.1|  276|Homo sapiens ADAMTS13 protein protein.
          Length = 276

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>BC103828-1|AAI03829.1|  276|Homo sapiens ADAMTS13 protein protein.
          Length = 276

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand
           factor-cleaving protease precursor protein.
          Length = 1427

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1371

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 13 protein.
          Length = 1340

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AL158826-24|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AL158826-23|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1340

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AL158826-22|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1371

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AJ420811-1|CAD12730.1|  344|Homo sapiens ADAMTS-13 protein,
           truncated variant protein.
          Length = 344

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, variant
           2 protein.
          Length = 1371

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.
          Length = 1340

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.
          Length = 1427

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand
           factor-cleaving protease protein.
          Length = 1427

 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 7   QDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTLASF 66
           Q+  E Y+LT +N+ + L  DPS+G                        + N  S+L S 
Sbjct: 97  QEDTERYVLTNLNIGAELLRDPSLG--AQFRVHLVKMVILTEPEGAPNITANLTSSLLSV 154

Query: 67  CRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
           C W + +NP++DT+P H D+ + +TR D+
Sbjct: 155 CGWSQTINPEDDTDPGHADLVLYITRFDL 183


>BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.
          Length = 1205

 Score = 53.2 bits (122), Expect = 2e-07
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 1/91 (1%)

Query: 4   FHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTL 63
           FH ++ ++ YLLT+MN+V+ +Y D S+G +                        N   +L
Sbjct: 271 FHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERG-NPSRSL 329

Query: 64  ASFCRWQEQLNPDNDTNPHHHDVAILVTRRD 94
            + CRW  Q    +  +  HHD AI +TR+D
Sbjct: 330 ENVCRWASQQQRSDLNHSEHHDHAIFLTRQD 360


>BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 3 protein.
          Length = 1205

 Score = 53.2 bits (122), Expect = 2e-07
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 1/91 (1%)

Query: 4   FHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTL 63
           FH ++ ++ YLLT+MN+V+ +Y D S+G +                        N   +L
Sbjct: 271 FHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERG-NPSRSL 329

Query: 64  ASFCRWQEQLNPDNDTNPHHHDVAILVTRRD 94
            + CRW  Q    +  +  HHD AI +TR+D
Sbjct: 330 ENVCRWASQQQRSDLNHSEHHDHAIFLTRQD 360


>AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.
          Length = 1081

 Score = 53.2 bits (122), Expect = 2e-07
 Identities = 36/106 (33%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M E H + ++  Y+LT+M  VS L+ D +IG+                       + +AD
Sbjct: 305 MVEKHGKGNVTTYILTVMK-VSGLFKDGTIGS--DINVVVVSLILLEQEPGGLLINHHAD 361

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
            +L SFC+WQ  L   N      HD AIL+T  DICS  + PC  L
Sbjct: 362 QSLNSFCQWQSALIGKNGKR---HDHAILLTGFDICSWKNEPCDTL 404


>AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.
          Length = 1201

 Score = 53.2 bits (122), Expect = 2e-07
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 1/91 (1%)

Query: 4   FHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTL 63
           FH ++ ++ YLLT+MN+V+ +Y D S+G +                        N   +L
Sbjct: 267 FHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERG-NPSRSL 325

Query: 64  ASFCRWQEQLNPDNDTNPHHHDVAILVTRRD 94
            + CRW  Q    +  +  HHD AI +TR+D
Sbjct: 326 ENVCRWASQQQRSDLNHSEHHDHAIFLTRQD 356


>BC030812-1|AAH30812.1|  339|Homo sapiens ADAMTS4 protein protein.
          Length = 339

 Score = 52.0 bits (119), Expect = 4e-07
 Identities = 33/93 (35%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ FH    L+ YLLT+M   +  +  PSI N                       S  A 
Sbjct: 230 MAAFHGA-GLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPS--AA 286

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRR 93
            TL SFC WQ  LN   D++P H D AIL TR+
Sbjct: 287 QTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQ 319


>AL590714-7|CAH72147.1|  339|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 339

 Score = 52.0 bits (119), Expect = 4e-07
 Identities = 33/93 (35%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M+ FH    L+ YLLT+M   +  +  PSI N                       S  A 
Sbjct: 230 MAAFHGA-GLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPS--AA 286

Query: 61  STLASFCRWQEQLNPDNDTNPHHHDVAILVTRR 93
            TL SFC WQ  LN   D++P H D AIL TR+
Sbjct: 287 QTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQ 319


>AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-proteinase
           protein.
          Length = 1211

 Score = 49.6 bits (113), Expect = 2e-06
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 3   EFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADST 62
           +FH ++ ++ YLLT+MN+V+ +Y D S+G +                        N   +
Sbjct: 280 QFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLSYGKSMSLIEIG-NPSQS 338

Query: 63  LASFCRWQE-QLNPDNDTNPHHHDVAILVTRRD 94
           L + CRW   Q  PD   +  +HD AI +TR+D
Sbjct: 339 LENVCRWAYLQQKPDTG-HDEYHDHAIFLTRQD 370


>AL358817-5|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1226

 Score = 48.8 bits (111), Expect = 4e-06
 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 4   FHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTL 63
           FH ++ ++ Y+LT+MN+V  +Y D S+G +                        N   +L
Sbjct: 274 FHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERG-NPSRSL 332

Query: 64  ASFCRWQEQLNPDNDTNPHHHDVAILVTRRD 94
              CRW       + ++  HHD  + +TR+D
Sbjct: 333 EQVCRWAHSQQRQDPSHAEHHDHVVFLTRQD 363


>AL358817-4|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1223

 Score = 48.8 bits (111), Expect = 4e-06
 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 4   FHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTL 63
           FH ++ ++ Y+LT+MN+V  +Y D S+G +                        N   +L
Sbjct: 274 FHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERG-NPSRSL 332

Query: 64  ASFCRWQEQLNPDNDTNPHHHDVAILVTRRD 94
              CRW       + ++  HHD  + +TR+D
Sbjct: 333 EQVCRWAHSQQRQDPSHAEHHDHVVFLTRQD 363


>AL355344-5|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1226

 Score = 48.8 bits (111), Expect = 4e-06
 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 4   FHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTL 63
           FH ++ ++ Y+LT+MN+V  +Y D S+G +                        N   +L
Sbjct: 274 FHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERG-NPSRSL 332

Query: 64  ASFCRWQEQLNPDNDTNPHHHDVAILVTRRD 94
              CRW       + ++  HHD  + +TR+D
Sbjct: 333 EQVCRWAHSQQRQDPSHAEHHDHVVFLTRQD 363


>AL355344-4|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1223

 Score = 48.8 bits (111), Expect = 4e-06
 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 4   FHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTL 63
           FH ++ ++ Y+LT+MN+V  +Y D S+G +                        N   +L
Sbjct: 274 FHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERG-NPSRSL 332

Query: 64  ASFCRWQEQLNPDNDTNPHHHDVAILVTRRD 94
              CRW       + ++  HHD  + +TR+D
Sbjct: 333 EQVCRWAHSQQRQDPSHAEHHDHVVFLTRQD 363


>AJ345098-1|CAC87943.1| 1223|Homo sapiens
           metalloprotease-disintegrin protease protein.
          Length = 1223

 Score = 48.8 bits (111), Expect = 4e-06
 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 4   FHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTL 63
           FH ++ ++ Y+LT+MN+V  +Y D S+G +                        N   +L
Sbjct: 274 FHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERG-NPSRSL 332

Query: 64  ASFCRWQEQLNPDNDTNPHHHDVAILVTRRD 94
              CRW       + ++  HHD  + +TR+D
Sbjct: 333 EQVCRWAHSQQRQDPSHAEHHDHVVFLTRQD 363


>AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.
          Length = 1159

 Score = 48.8 bits (111), Expect = 4e-06
 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 4   FHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTL 63
           FH ++ ++ Y+LT+MN+V  +Y D S+G +                        N   +L
Sbjct: 207 FHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERG-NPSRSL 265

Query: 64  ASFCRWQEQLNPDNDTNPHHHDVAILVTRRD 94
              CRW       + ++  HHD  + +TR+D
Sbjct: 266 EQVCRWAHSQQRQDPSHAEHHDHVVFLTRQD 296


>AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and
           metalloprotease with thrombospondin type 1 motif 14 prec
           protein.
          Length = 1223

 Score = 48.8 bits (111), Expect = 4e-06
 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 4   FHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNADSTL 63
           FH ++ ++ Y+LT+MN+V  +Y D S+G +                        N   +L
Sbjct: 274 FHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERG-NPSRSL 332

Query: 64  ASFCRWQEQLNPDNDTNPHHHDVAILVTRRD 94
              CRW       + ++  HHD  + +TR+D
Sbjct: 333 EQVCRWAHSQQRQDPSHAEHHDHVVFLTRQD 363


>AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.
          Length = 1207

 Score = 48.0 bits (109), Expect = 6e-06
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 13/114 (11%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M  +H  D+   ++LTI+NMV +L+   S+G                          + +
Sbjct: 337 MVSYHGADAARRFILTILNMVFNLFQHKSLG--VQVNLRVIKLILLHETPPELYIGHHGE 394

Query: 61  STLASFCRWQ-EQLNPDND------TNPHHH----DVAILVTRRDICSQHDSPC 103
             L SFC+WQ E+    ND      TN        D AIL+TR+D C   D PC
Sbjct: 395 KMLESFCKWQHEEFGKKNDIHLEMSTNWGEDMTSVDAAILITRKDFCVHKDEPC 448


>DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif 17 protein.
          Length = 1095

 Score = 45.2 bits (102), Expect = 4e-05
 Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 13/114 (11%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M ++H  ++ + ++LT+MNMV +++   S+G                          + +
Sbjct: 244 MVQYHGAEAAQRFILTVMNMVYNMFQHQSLG--IKINIQVTKLVLLRQRPAKLSIGHHGE 301

Query: 61  STLASFCRWQEQ-----------LNPDNDTNPHHHDVAILVTRRDICSQHDSPC 103
            +L SFC WQ +             P    +P   D A+ VTR D C   D PC
Sbjct: 302 RSLESFCHWQNEEYGGARYLGNNQVPGGKDDPPLVDAAVFVTRTDFCVHKDEPC 355


>AY532929-1|AAS54901.1|   90|Homo sapiens von Willebrand
          factor-cleaving protease protein.
          Length = 90

 Score = 45.2 bits (102), Expect = 4e-05
 Identities = 16/40 (40%), Positives = 27/40 (67%)

Query: 56 STNADSTLASFCRWQEQLNPDNDTNPHHHDVAILVTRRDI 95
          + N  S+L S C W + +NP++DT+P H D+ + +TR D+
Sbjct: 6  TANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDL 45


>AK131344-1|BAD18500.1|  502|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16363 fis, clone THYMU2031139, weakly  similar
           to Homo sapiens zinc metalloprotease ADAMTS7 (ADAMTS7)
           mRNA. ).
          Length = 502

 Score = 45.2 bits (102), Expect = 4e-05
 Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 13/114 (11%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M ++H  ++ + ++LT+MNMV +++   S+G                          + +
Sbjct: 1   MVQYHGAEAAQRFILTVMNMVYNMFQHQSLG--IKINIQVTKLVLLRQRPAKLSIGHHGE 58

Query: 61  STLASFCRWQEQ-----------LNPDNDTNPHHHDVAILVTRRDICSQHDSPC 103
            +L SFC WQ +             P    +P   D A+ VTR D C   D PC
Sbjct: 59  RSLESFCHWQNEEYGGARYLGNNQVPGGKDDPPLVDAAVFVTRTDFCVHKDEPC 112


>AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease
           disintegrin 17, with thrombospondin domains protein.
          Length = 1095

 Score = 45.2 bits (102), Expect = 4e-05
 Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 13/114 (11%)

Query: 1   MSEFHDQDSLEIYLLTIMNMVSSLYMDPSIGNYXXXXXXXXXXXXXXXXXXXXXXSTNAD 60
           M ++H  ++ + ++LT+MNMV +++   S+G                          + +
Sbjct: 244 MVQYHGAEAAQRFILTVMNMVYNMFQHQSLG--IKINIQVTKLVLLRQRPAKLSIGHHGE 301

Query: 61  STLASFCRWQEQ-----------LNPDNDTNPHHHDVAILVTRRDICSQHDSPC 103
            +L SFC WQ +             P    +P   D A+ VTR D C   D PC
Sbjct: 302 RSLESFCHWQNEEYGGARYLGNNQVPGGKDDPPLVDAAVFVTRTDFCVHKDEPC 355


>AB209515-1|BAD92752.1|  847|Homo sapiens a disintegrin-like and
           metalloprotease (reprolysin type) with thrombospondin ty
           protein.
          Length = 847

 Score = 41.9 bits (94), Expect = 4e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 7/56 (12%)

Query: 58  NADSTLASFCRWQEQL-------NPDNDTNPHHHDVAILVTRRDICSQHDSPCSLL 106
           +A  +L SFC+WQ+ +       N   +    +HD A+L+TR DIC   + PC  L
Sbjct: 60  HAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTL 115


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.319    0.132    0.405 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 12,859,296
Number of Sequences: 224733
Number of extensions: 331078
Number of successful extensions: 679
Number of sequences better than 10.0: 79
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 511
Number of HSP's gapped (non-prelim): 80
length of query: 110
length of database: 73,234,838
effective HSP length: 79
effective length of query: 31
effective length of database: 55,480,931
effective search space: 1719908861
effective search space used: 1719908861
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 58 (27.5 bits)

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