Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001428-TA|BGIBMGA001428-PA|IPR001762|Disintegrin,
IPR006025|Peptidase M, neutral zinc metallopeptidases, zinc-binding
site, IPR001590|Peptidase M12B, ADAM/reprolysin
(648 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U92649-1|AAC39721.1| 824|Homo sapiens snake venom-like protease... 344 5e-94
U86755-1|AAB51586.1| 824|Homo sapiens TNF-alpha converting enzy... 344 5e-94
U69612-1|AAB53014.1| 694|Homo sapiens TNF-alpha converting enzy... 344 5e-94
U69611-1|AAB51514.1| 824|Homo sapiens TNF-alpha converting enzy... 344 5e-94
AC080162-4|AAY14859.1| 543|Homo sapiens unknown protein. 279 3e-74
AF009615-1|AAC51766.1| 748|Homo sapiens ADAM10 protein. 220 1e-56
Z48579-1|CAA88463.1| 691|Homo sapiens disintegrin-metalloprotea... 201 5e-51
BC126253-1|AAI26254.1| 512|Homo sapiens ADAM10 protein protein. 189 2e-47
DQ995342-1|ABI97387.1| 813|Homo sapiens ADAM metallopeptidase d... 101 8e-21
AY358314-1|AAQ88680.1| 813|Homo sapiens Adam33 protein. 101 8e-21
AL356755-2|CAI23465.1| 813|Homo sapiens ADAM metallopeptidase d... 101 8e-21
AL356755-1|CAM28348.1| 812|Homo sapiens ADAM metallopeptidase d... 101 8e-21
AL109804-2|CAI18840.1| 813|Homo sapiens ADAM metallopeptidase d... 101 8e-21
AL109804-1|CAM26955.1| 812|Homo sapiens ADAM metallopeptidase d... 101 8e-21
AF466288-1|AAM80483.1| 812|Homo sapiens a disintegrin and metal... 101 8e-21
AF466287-1|AAM80482.1| 812|Homo sapiens a disintegrin and metal... 101 8e-21
AB055891-1|BAB83092.1| 813|Homo sapiens metalloprotease disinte... 101 8e-21
Y13786-1|CAC20585.1| 918|Homo sapiens meltrin-beta/ADAM 19 homo... 93 3e-18
AF311317-1|AAK07852.1| 918|Homo sapiens disintegrin and metallo... 93 3e-18
AF134707-1|AAF22162.1| 857|Homo sapiens disintegrin and metallo... 93 3e-18
U46005-1|AAC51112.1| 814|Homo sapiens MDC15 protein. 92 6e-18
U41767-1|AAC50404.1| 814|Homo sapiens metargidin precursor prot... 92 6e-18
U41766-1|AAC50403.1| 819|Homo sapiens metalloprotease/disintegr... 92 6e-18
D14665-1|BAA03499.2| 703|Homo sapiens KIAA0021 protein protein. 92 6e-18
BT009764-1|AAP88766.1| 814|Homo sapiens a disintegrin and metal... 92 6e-18
BC126406-1|AAI26407.1| 712|Homo sapiens ADAM9 protein protein. 92 6e-18
BC014566-1|AAH14566.1| 814|Homo sapiens ADAM metallopeptidase d... 92 6e-18
AY576417-1|AAS73000.1| 797|Homo sapiens ADAM15 isoform 8 protein. 92 6e-18
AY560601-1|AAS72999.1| 822|Homo sapiens ADAM15 isoform 7b protein. 92 6e-18
AY560600-1|AAS72998.1| 821|Homo sapiens ADAM15 isoform 7a protein. 92 6e-18
AY560599-1|AAS72997.1| 863|Homo sapiens ADAM15 isoform 6b protein. 92 6e-18
AY560598-1|AAS72996.1| 862|Homo sapiens ADAM15 isoform 6a protein. 92 6e-18
AY560597-1|AAS72995.1| 838|Homo sapiens ADAM15 isoform 5 protein. 92 6e-18
AY560596-1|AAS72994.1| 839|Homo sapiens ADAM15 isoform 4a protein. 92 6e-18
AY560595-1|AAS72993.1| 796|Homo sapiens ADAM15 isoform 3a protein. 92 6e-18
AY560594-1|AAS72992.1| 814|Homo sapiens ADAM15 isoform 2 protein. 92 6e-18
AY560593-1|AAS72991.1| 772|Homo sapiens ADAM15 isoform 1 protein. 92 6e-18
AY518542-1|AAR99331.1| 772|Homo sapiens ADAM-15 precursor protein. 92 6e-18
AL691442-13|CAI15327.1| 814|Homo sapiens ADAM metallopeptidase ... 92 6e-18
AL451085-35|CAI13274.1| 814|Homo sapiens ADAM metallopeptidase ... 92 6e-18
AF495383-1|AAM49575.1| 655|Homo sapiens disintegrin/metalloprot... 92 6e-18
AF314227-11|AAS72298.1| 797|Homo sapiens ADAM15 isoform 8 protein. 92 6e-18
AF314227-10|AAS48596.1| 821|Homo sapiens ADAM15 isoform 7a prot... 92 6e-18
AF314227-9|AAS48597.1| 822|Homo sapiens ADAM15 isoform 7b protein. 92 6e-18
AF314227-8|AAS48590.1| 772|Homo sapiens ADAM15 isoform 1 protein. 92 6e-18
AF314227-7|AAS48591.1| 796|Homo sapiens ADAM15 isoform 3a protein. 92 6e-18
AF314227-6|AAM44189.1| 814|Homo sapiens ADAM15 isoform 2 protein. 92 6e-18
AF314227-5|AAS48593.1| 838|Homo sapiens ADAM15 isoform 5 protein. 92 6e-18
AF314227-4|AAS48594.1| 862|Homo sapiens ADAM15 isoform 6a protein. 92 6e-18
AF314227-3|AAS48592.1| 839|Homo sapiens ADAM15 isoform 4a protein. 92 6e-18
AF314227-2|AAS48595.1| 863|Homo sapiens ADAM15 isoform 6b protein. 92 6e-18
AB209157-1|BAD92394.1| 859|Homo sapiens ADAM15 isoform 6a varia... 92 6e-18
BC060804-1|AAH60804.1| 737|Homo sapiens ADAM metallopeptidase d... 89 6e-17
AY358878-1|AAQ89237.1| 735|Homo sapiens ADAM-12 protein. 89 6e-17
AL589787-6|CAI40683.1| 738|Homo sapiens ADAM metallopeptidase d... 89 6e-17
AL589787-5|CAI40682.1| 909|Homo sapiens ADAM metallopeptidase d... 89 6e-17
AF023477-1|AAC08703.2| 738|Homo sapiens meltrin-S protein. 89 6e-17
AF023476-1|AAC08702.2| 909|Homo sapiens meltrin-L precursor pro... 89 6e-17
BC132765-1|AAI32766.1| 832|Homo sapiens ADAM metallopeptidase d... 86 3e-16
BC132763-1|AAI32764.1| 832|Homo sapiens ADAM metallopeptidase d... 86 3e-16
AJ005580-1|CAC20565.1| 832|Homo sapiens Adam23 protein protein. 86 3e-16
AB009672-1|BAA32351.1| 832|Homo sapiens MDC3 protein. 86 3e-16
DQ202398-1|ABA43715.1| 465|Homo sapiens ADAM21-like protein pro... 82 7e-15
AL691442-12|CAI15328.1| 520|Homo sapiens ADAM metallopeptidase ... 81 9e-15
AL451085-36|CAI13273.1| 520|Homo sapiens ADAM metallopeptidase ... 81 9e-15
BC109025-1|AAI09026.1| 721|Homo sapiens ADAM21 protein protein. 81 2e-14
BC109024-1|AAI09025.1| 722|Homo sapiens ADAM metallopeptidase d... 81 2e-14
AF158644-1|AAD55255.1| 722|Homo sapiens metalloproteinase-disin... 81 2e-14
BC025378-1|AAH25378.2| 776|Homo sapiens ADAM metallopeptidase d... 80 2e-14
AJ242015-1|CAB42085.1| 775|Homo sapiens eMDC II protein protein. 80 2e-14
AF158643-1|AAD55254.1| 726|Homo sapiens metalloproteinase-disin... 80 2e-14
AF137335-1|AAD25100.1| 540|Homo sapiens metalloprotease disinte... 80 2e-14
AF137334-1|AAD25099.1| 775|Homo sapiens metalloprotease disinte... 80 2e-14
AF029899-1|AAC52041.1| 726|Homo sapiens ADAM 20 protein. 80 2e-14
AC009225-1|AAX93195.1| 579|Homo sapiens unknown protein. 80 3e-14
BC062687-1|AAH62687.1| 209|Homo sapiens ADAM17 protein protein. 79 5e-14
AF171931-1|AAF03779.1| 787|Homo sapiens metallaproteinase-disin... 78 8e-14
AF171930-1|AAF03778.1| 766|Homo sapiens metallaproteinase-disin... 78 8e-14
AF171929-1|AAF03777.1| 820|Homo sapiens metallaproteinase-disin... 78 8e-14
AF134708-1|AAF22163.1| 820|Homo sapiens disintegrin and metallo... 78 8e-14
AF029900-1|AAC52042.1| 542|Homo sapiens ADAM 21 protein. 78 8e-14
AC105914-1|AAY41055.1| 820|Homo sapiens unknown protein. 78 8e-14
D26579-1|BAA05626.1| 824|Homo sapiens transmembrane protein pro... 78 1e-13
BC115404-1|AAI15405.1| 824|Homo sapiens ADAM8 protein protein. 78 1e-13
AF171932-1|AAF03780.1| 790|Homo sapiens metallaproteinase-disin... 77 2e-13
BC028372-1|AAH28372.1| 790|Homo sapiens ADAM metallopeptidase d... 77 3e-13
AY358734-1|AAQ89096.1| 790|Homo sapiens ADAM30 protein. 77 3e-13
AL359752-8|CAI18978.1| 790|Homo sapiens ADAM metallopeptidase d... 77 3e-13
AF171933-1|AAF03781.1| 781|Homo sapiens metallaproteinase-disin... 76 3e-13
D31872-2|BAA06671.1| 518|Homo sapiens metalloprotease/disintegr... 73 2e-12
D31872-1|BAA06670.1| 664|Homo sapiens metalloprotease/disintegr... 73 2e-12
D17390-1|BAA04213.1| 524|Homo sapiens MDC protein protein. 73 2e-12
AB009675-1|BAA32352.1| 769|Homo sapiens MDC/ADAM11 protein. 73 2e-12
BC125113-1|AAI25114.1| 692|Homo sapiens ADAM33 protein protein. 73 3e-12
BC125118-1|AAI25119.1| 870|Homo sapiens ADAM metallopeptidase d... 71 1e-11
AF158637-1|AAD55251.1| 867|Homo sapiens metalloproteinase-disin... 71 1e-11
AF155382-1|AAF73289.1| 906|Homo sapiens metalloprotease-like, d... 71 1e-11
AF155381-1|AAF73288.1| 899|Homo sapiens metalloprotease-like, d... 71 1e-11
AF073291-1|AAF22476.2| 870|Homo sapiens MDC2 protein. 71 1e-11
AB009671-2|BAA32350.1| 823|Homo sapiens MDC2 beta protein. 71 1e-11
AB009671-1|BAA32349.1| 859|Homo sapiens MDC2 alpha protein. 71 1e-11
BC043207-1|AAH43207.2| 559|Homo sapiens ADAM7 protein protein. 71 2e-11
AF215824-1|AAG43987.1| 754|Homo sapiens a disintegrin and metal... 71 2e-11
BC034975-1|AAH34975.1| 787|Homo sapiens ADAM metallopeptidase d... 70 2e-11
BC030698-1|AAH30698.1| 787|Homo sapiens ADAM metallopeptidase d... 70 2e-11
BC030014-1|AAH30014.1| 787|Homo sapiens ADAM metallopeptidase d... 70 2e-11
BC028702-1|AAH28702.1| 787|Homo sapiens ADAM metallopeptidase d... 70 2e-11
BC026169-1|AAH26169.1| 787|Homo sapiens ADAM metallopeptidase d... 70 2e-11
BC026085-1|AAH26085.1| 787|Homo sapiens ADAM metallopeptidase d... 70 2e-11
AY358739-1|AAQ89099.1| 787|Homo sapiens similar to MDC family p... 70 2e-11
AC092206-1|AAX93091.1| 131|Homo sapiens unknown protein. 70 3e-11
AF090327-1|AAC36742.1| 588|Homo sapiens sperm maturation-relate... 68 9e-11
U52370-1|AAC51110.1| 735|Homo sapiens fertilin beta protein. 66 3e-10
U38805-1|AAD04206.1| 734|Homo sapiens fertilin beta protein. 66 3e-10
BC064547-1|AAH64547.1| 579|Homo sapiens ADAM2 protein protein. 66 3e-10
BC034957-1|AAH34957.1| 716|Homo sapiens ADAM2 protein protein. 66 3e-10
AJ133005-1|CAB40813.1| 735|Homo sapiens fertilin beta protein p... 66 3e-10
BC121045-1|AAI21046.1| 739|Homo sapiens ADAM metallopeptidase d... 60 2e-08
AY358321-1|AAQ88687.1| 715|Homo sapiens ADAM18 protein. 60 2e-08
AJ133004-1|CAB40812.1| 739|Homo sapiens tMDC III protein protein. 60 2e-08
X99374-1|CAA67753.1| 735|Homo sapiens fertilin beta protein. 58 7e-08
AC073195-1|AAX93142.1| 150|Homo sapiens unknown protein. 48 8e-05
BC033132-1|AAH33132.1| 488|Homo sapiens ADAM19 protein protein. 48 1e-04
BC024214-1|AAH24214.2| 488|Homo sapiens ADAM19 protein protein. 48 1e-04
AF158642-1|AAD55253.1| 88|Homo sapiens metalloproteinase-disin... 45 0.001
AY172952-1|AAO45696.1| 629|Homo sapiens metalloproteinase 12-li... 44 0.002
AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein. 42 0.007
DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase w... 42 0.009
AK131344-1|BAD18500.1| 502|Homo sapiens protein ( Homo sapiens ... 42 0.009
AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disinte... 42 0.009
BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase w... 39 0.063
AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein. 39 0.063
AF140675-1|AAD56358.1| 997|Homo sapiens zinc metalloprotease AD... 39 0.063
AB209497-1|BAD92734.1| 527|Homo sapiens a disintegrin and metal... 39 0.063
BC036515-1|AAH36515.1| 967|Homo sapiens ADAM metallopeptidase w... 38 0.15
AP001697-1|BAA95502.1| 967|Homo sapiens metalloprotease with th... 38 0.15
AF207664-1|AAF23772.1| 967|Homo sapiens matrix metalloprotease ... 38 0.15
AF060152-1|AAD48080.1| 950|Homo sapiens METH1 protein protein. 38 0.15
AB037767-1|BAA92584.1| 999|Homo sapiens KIAA1346 protein protein. 38 0.15
Y13323-1|CAA73764.2| 470|Homo sapiens disintegrin-protease prot... 37 0.19
BC074878-1|AAH74878.1| 470|Homo sapiens ADAM-like, decysin 1 pr... 37 0.19
BC074877-1|AAH74877.1| 470|Homo sapiens ADAM-like, decysin 1 pr... 37 0.19
BC069582-1|AAH69582.1| 470|Homo sapiens ADAM-like, decysin 1 pr... 37 0.19
AF170084-1|AAF15317.1| 967|Homo sapiens metalloproteinase with ... 37 0.19
AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar t... 36 0.34
AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar t... 36 0.34
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 36 0.59
AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein. 36 0.59
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 36 0.59
BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein. 35 1.0
AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and ... 35 1.0
DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase w... 34 1.4
AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand factor-c... 34 1.4
AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase ... 34 1.4
AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase ... 34 1.4
AL158826-24|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase ... 34 1.4
AL158826-22|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase ... 34 1.4
AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, vari... 34 1.4
AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein. 34 1.4
AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand factor-c... 34 1.4
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 33 2.4
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 33 2.4
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein. 33 2.4
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 33 2.4
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 33 2.4
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 33 2.4
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 33 2.4
BC127016-1|AAI27017.1| 259|Homo sapiens KRTAP10-8 protein protein. 33 3.1
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 33 3.1
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 33 3.1
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 33 3.1
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 33 3.1
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 33 3.1
AB076355-1|BAD01542.1| 259|Homo sapiens keratin associated prot... 33 3.1
BC008720-1|AAH08720.1| 422|Homo sapiens cysteine-rich with EGF-... 33 4.2
AY358363-1|AAQ88729.1| 420|Homo sapiens CRELD1 protein. 33 4.2
AF452623-1|AAM75206.1| 420|Homo sapiens cysteine-rich with EGF-... 33 4.2
X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein. 32 5.5
M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein. 32 5.5
BC053863-1|AAH53863.1| 709|Homo sapiens YTH domain containing 1... 32 5.5
BC041119-1|AAH41119.1| 727|Homo sapiens YTH domain containing 1... 32 5.5
AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachio... 32 5.5
AK056430-1|BAB71181.1| 658|Homo sapiens protein ( Homo sapiens ... 32 5.5
AC074378-1|AAY41024.1| 658|Homo sapiens unknown protein. 32 5.5
AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein pro... 32 5.5
AB209515-1|BAD92752.1| 847|Homo sapiens a disintegrin-like and ... 32 7.3
AB076353-1|BAD01540.1| 365|Homo sapiens keratin associated prot... 32 7.3
AB076348-1|BAD01535.1| 255|Homo sapiens keratin associated prot... 32 7.3
X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein. 31 9.6
BC125049-1|AAI25050.1| 401|Homo sapiens keratin associated prot... 31 9.6
BC125048-1|AAI25049.1| 401|Homo sapiens keratin associated prot... 31 9.6
BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase w... 31 9.6
BC004107-1|AAH04107.1| 344|Homo sapiens follistatin protein. 31 9.6
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 31 9.6
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 31 9.6
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 31 9.6
AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein. 31 9.6
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 31 9.6
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 31 9.6
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 31 9.6
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 31 9.6
AB076351-1|BAD01538.1| 401|Homo sapiens keratin associated prot... 31 9.6
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 31 9.6
>U92649-1|AAC39721.1| 824|Homo sapiens snake venom-like protease
protein.
Length = 824
Score = 344 bits (846), Expect = 5e-94
Identities = 172/356 (48%), Positives = 229/356 (64%), Gaps = 22/356 (6%)
Query: 213 RTKRQSDYEYTPTKTRCPLLLVADYRFFQEMGASNTKTTISYLISLIDRVHKIYNDTLWQ 272
R KR++D + P K C LL+VAD+RF++ MG TT +YLI LIDRV IY +T W
Sbjct: 211 RVKRRADPD--PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSW- 267
Query: 273 DRQDMDGFKGMGFVIKKILVHSEPTRVRGGEAHYNMVR-------EKWDVRNLLEVFSRE 325
D GFKG G I++I + P V+ GE HYNM + + WDV+ LLE FS +
Sbjct: 268 ---DNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFD 324
Query: 326 YSHK--DFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFK--NGYTLYLNSGL 381
+ + CLAHLFT F+ G LGLAYVGSPR NS GG+C Y+ +YLNSGL
Sbjct: 325 IAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGL 384
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPD-VAECSPAASQGGSYLMYTYSVSGY 440
+S++N YG+ ++T+EADLVT HE GHN+G+EHDPD +AEC+P QGG Y+MY +VSG
Sbjct: 385 TSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGD 443
Query: 441 DVNNKRFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCC 500
NNK FS CS +SI K +++K+ CF E CGN RV+ GEECD G++ +ND CC
Sbjct: 444 HENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYL-NNDTCC 502
Query: 501 DKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ +C L+ +G CSD+NSPCC C F C+EA ++ C+G + C G S++CP
Sbjct: 503 NSDCTLK--EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECP 556
Score = 78.2 bits (184), Expect = 8e-14
Identities = 56/172 (32%), Positives = 82/172 (47%), Gaps = 10/172 (5%)
Query: 12 ASIQSTGIVKRGAKLSNHPYNTIKEVRFKTLGKDFRLILHPQSSVLHSNFKAYSVDADGK 71
++IQ + KR + S H T+ + F L + F+L L + NFK VD GK
Sbjct: 48 SNIQQHSVRKRDLQTSTH-VETL--LTFSALKRHFKLYLTSSTERFSQNFKVVVVD--GK 102
Query: 72 ETTVHVDR-ENFFTGRVFGETKSDVKLHMEDGVMTGIIHTPDETYHVEPSWRHLPDLDGK 130
+ + + ++FFTG V GE S V H+ D + I+T Y++EP WR + D K
Sbjct: 103 NESEYTAKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDK 162
Query: 131 SMITYRSSDIRYSWAGDAIPNKPRVCGYVKEGKELEDDSDDVQEEYDIELKH 182
M+ Y+S DI+ + P+VCGY+K E V E EL H
Sbjct: 163 RMLVYKSEDIK----NVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVH 210
Score = 66.1 bits (154), Expect = 4e-10
Identities = 28/53 (52%), Positives = 37/53 (69%)
Query: 558 GVCEKTIQDVVERFWDIIEDININNVLGFLRDNIVGVVVLVTAFIWIPASCVV 610
G CEK +QDV+ERFWD I+ ++IN FL DNIVG V++ + WIP S +V
Sbjct: 639 GKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILV 691
>U86755-1|AAB51586.1| 824|Homo sapiens TNF-alpha converting enzyme
protein.
Length = 824
Score = 344 bits (846), Expect = 5e-94
Identities = 172/356 (48%), Positives = 229/356 (64%), Gaps = 22/356 (6%)
Query: 213 RTKRQSDYEYTPTKTRCPLLLVADYRFFQEMGASNTKTTISYLISLIDRVHKIYNDTLWQ 272
R KR++D + P K C LL+VAD+RF++ MG TT +YLI LIDRV IY +T W
Sbjct: 211 RVKRRADPD--PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSW- 267
Query: 273 DRQDMDGFKGMGFVIKKILVHSEPTRVRGGEAHYNMVR-------EKWDVRNLLEVFSRE 325
D GFKG G I++I + P V+ GE HYNM + + WDV+ LLE FS +
Sbjct: 268 ---DNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFD 324
Query: 326 YSHK--DFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFK--NGYTLYLNSGL 381
+ + CLAHLFT F+ G LGLAYVGSPR NS GG+C Y+ +YLNSGL
Sbjct: 325 IAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGL 384
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPD-VAECSPAASQGGSYLMYTYSVSGY 440
+S++N YG+ ++T+EADLVT HE GHN+G+EHDPD +AEC+P QGG Y+MY +VSG
Sbjct: 385 TSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGD 443
Query: 441 DVNNKRFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCC 500
NNK FS CS +SI K +++K+ CF E CGN RV+ GEECD G++ +ND CC
Sbjct: 444 HENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYL-NNDTCC 502
Query: 501 DKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ +C L+ +G CSD+NSPCC C F C+EA ++ C+G + C G S++CP
Sbjct: 503 NSDCTLK--EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECP 556
Score = 79.4 bits (187), Expect = 4e-14
Identities = 56/171 (32%), Positives = 80/171 (46%), Gaps = 8/171 (4%)
Query: 12 ASIQSTGIVKRGAKLSNHPYNTIKEVRFKTLGKDFRLILHPQSSVLHSNFKAYSVDADGK 71
++IQ + KR + S H T+ + F L + F+L L + NFK VD
Sbjct: 48 SNIQQHSVRKRDLQTSTH-VETL--LTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKN- 103
Query: 72 ETTVHVDRENFFTGRVFGETKSDVKLHMEDGVMTGIIHTPDETYHVEPSWRHLPDLDGKS 131
E+ V ++FFTG V GE S V H+ D + I+T Y++EP WR + D K
Sbjct: 104 ESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKR 163
Query: 132 MITYRSSDIRYSWAGDAIPNKPRVCGYVKEGKELEDDSDDVQEEYDIELKH 182
M+ Y+S DI+ + P+VCGY+K E V E EL H
Sbjct: 164 MLVYKSEDIK----NVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVH 210
Score = 66.1 bits (154), Expect = 4e-10
Identities = 28/53 (52%), Positives = 37/53 (69%)
Query: 558 GVCEKTIQDVVERFWDIIEDININNVLGFLRDNIVGVVVLVTAFIWIPASCVV 610
G CEK +QDV+ERFWD I+ ++IN FL DNIVG V++ + WIP S +V
Sbjct: 639 GKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILV 691
>U69612-1|AAB53014.1| 694|Homo sapiens TNF-alpha converting enzyme
precursor protein.
Length = 694
Score = 344 bits (846), Expect = 5e-94
Identities = 172/356 (48%), Positives = 229/356 (64%), Gaps = 22/356 (6%)
Query: 213 RTKRQSDYEYTPTKTRCPLLLVADYRFFQEMGASNTKTTISYLISLIDRVHKIYNDTLWQ 272
R KR++D + P K C LL+VAD+RF++ MG TT +YLI LIDRV IY +T W
Sbjct: 211 RVKRRADPD--PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSW- 267
Query: 273 DRQDMDGFKGMGFVIKKILVHSEPTRVRGGEAHYNMVR-------EKWDVRNLLEVFSRE 325
D GFKG G I++I + P V+ GE HYNM + + WDV+ LLE FS +
Sbjct: 268 ---DNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFD 324
Query: 326 YSHK--DFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFK--NGYTLYLNSGL 381
+ + CLAHLFT F+ G LGLAYVGSPR NS GG+C Y+ +YLNSGL
Sbjct: 325 IAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGL 384
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPD-VAECSPAASQGGSYLMYTYSVSGY 440
+S++N YG+ ++T+EADLVT HE GHN+G+EHDPD +AEC+P QGG Y+MY +VSG
Sbjct: 385 TSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGD 443
Query: 441 DVNNKRFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCC 500
NNK FS CS +SI K +++K+ CF E CGN RV+ GEECD G++ +ND CC
Sbjct: 444 HENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYL-NNDTCC 502
Query: 501 DKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ +C L+ +G CSD+NSPCC C F C+EA ++ C+G + C G S++CP
Sbjct: 503 NSDCTLK--EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECP 556
Score = 79.4 bits (187), Expect = 4e-14
Identities = 56/171 (32%), Positives = 80/171 (46%), Gaps = 8/171 (4%)
Query: 12 ASIQSTGIVKRGAKLSNHPYNTIKEVRFKTLGKDFRLILHPQSSVLHSNFKAYSVDADGK 71
++IQ + KR + S H T+ + F L + F+L L + NFK VD
Sbjct: 48 SNIQQHSVRKRDLQTSTH-VETL--LTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKN- 103
Query: 72 ETTVHVDRENFFTGRVFGETKSDVKLHMEDGVMTGIIHTPDETYHVEPSWRHLPDLDGKS 131
E+ V ++FFTG V GE S V H+ D + I+T Y++EP WR + D K
Sbjct: 104 ESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKR 163
Query: 132 MITYRSSDIRYSWAGDAIPNKPRVCGYVKEGKELEDDSDDVQEEYDIELKH 182
M+ Y+S DI+ + P+VCGY+K E V E EL H
Sbjct: 164 MLVYKSEDIK----NVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVH 210
Score = 66.1 bits (154), Expect = 4e-10
Identities = 28/53 (52%), Positives = 37/53 (69%)
Query: 558 GVCEKTIQDVVERFWDIIEDININNVLGFLRDNIVGVVVLVTAFIWIPASCVV 610
G CEK +QDV+ERFWD I+ ++IN FL DNIVG V++ + WIP S +V
Sbjct: 639 GKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILV 691
>U69611-1|AAB51514.1| 824|Homo sapiens TNF-alpha converting enzyme
protein.
Length = 824
Score = 344 bits (846), Expect = 5e-94
Identities = 172/356 (48%), Positives = 229/356 (64%), Gaps = 22/356 (6%)
Query: 213 RTKRQSDYEYTPTKTRCPLLLVADYRFFQEMGASNTKTTISYLISLIDRVHKIYNDTLWQ 272
R KR++D + P K C LL+VAD+RF++ MG TT +YLI LIDRV IY +T W
Sbjct: 211 RVKRRADPD--PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSW- 267
Query: 273 DRQDMDGFKGMGFVIKKILVHSEPTRVRGGEAHYNMVR-------EKWDVRNLLEVFSRE 325
D GFKG G I++I + P V+ GE HYNM + + WDV+ LLE FS +
Sbjct: 268 ---DNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFD 324
Query: 326 YSHK--DFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFK--NGYTLYLNSGL 381
+ + CLAHLFT F+ G LGLAYVGSPR NS GG+C Y+ +YLNSGL
Sbjct: 325 IAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGL 384
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPD-VAECSPAASQGGSYLMYTYSVSGY 440
+S++N YG+ ++T+EADLVT HE GHN+G+EHDPD +AEC+P QGG Y+MY +VSG
Sbjct: 385 TSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGD 443
Query: 441 DVNNKRFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCC 500
NNK FS CS +SI K +++K+ CF E CGN RV+ GEECD G++ +ND CC
Sbjct: 444 HENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYL-NNDTCC 502
Query: 501 DKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ +C L+ +G CSD+NSPCC C F C+EA ++ C+G + C G S++CP
Sbjct: 503 NSDCTLK--EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECP 556
Score = 79.4 bits (187), Expect = 4e-14
Identities = 56/171 (32%), Positives = 80/171 (46%), Gaps = 8/171 (4%)
Query: 12 ASIQSTGIVKRGAKLSNHPYNTIKEVRFKTLGKDFRLILHPQSSVLHSNFKAYSVDADGK 71
++IQ + KR + S H T+ + F L + F+L L + NFK VD
Sbjct: 48 SNIQQHSVRKRDLQTSTH-VETL--LTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKN- 103
Query: 72 ETTVHVDRENFFTGRVFGETKSDVKLHMEDGVMTGIIHTPDETYHVEPSWRHLPDLDGKS 131
E+ V ++FFTG V GE S V H+ D + I+T Y++EP WR + D K
Sbjct: 104 ESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKR 163
Query: 132 MITYRSSDIRYSWAGDAIPNKPRVCGYVKEGKELEDDSDDVQEEYDIELKH 182
M+ Y+S DI+ + P+VCGY+K E V E EL H
Sbjct: 164 MLVYKSEDIK----NVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVH 210
Score = 66.1 bits (154), Expect = 4e-10
Identities = 28/53 (52%), Positives = 37/53 (69%)
Query: 558 GVCEKTIQDVVERFWDIIEDININNVLGFLRDNIVGVVVLVTAFIWIPASCVV 610
G CEK +QDV+ERFWD I+ ++IN FL DNIVG V++ + WIP S +V
Sbjct: 639 GKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILV 691
>AC080162-4|AAY14859.1| 543|Homo sapiens unknown protein.
Length = 543
Score = 279 bits (683), Expect = 3e-74
Identities = 135/279 (48%), Positives = 181/279 (64%), Gaps = 16/279 (5%)
Query: 290 ILVHSEPTRVRGGEAHYNMVR-------EKWDVRNLLEVFSREYSHK--DFCLAHLFTDL 340
I + P V+ GE HYNM + + WDV+ LLE FS + + + CLAHLFT
Sbjct: 1 IRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQ 60
Query: 341 KFEGGILGLAYVGSPRRNSVGGICTPEYFK--NGYTLYLNSGLSSSRNHYGQRVITREAD 398
F+ G LGLAYVGSPR NS GG+C Y+ +YLNSGL+S++N YG+ ++T+EAD
Sbjct: 61 DFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKN-YGKTILTKEAD 119
Query: 399 LVTAHEFGHNWGSEHDPD-VAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRK 457
LVT HE GHN+G+EHDPD +AEC+P QGG Y+MY +VSG NNK FS CS +SI K
Sbjct: 120 LVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYK 179
Query: 458 VLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDK 517
+++K+ CF E CGN RV+ GEECD G++ +ND CC+ +C L+ +G CSD+
Sbjct: 180 TIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYL-NNDTCCNSDCTLK--EGVQCSDR 236
Query: 518 NSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
NSPCC C F C+EA ++ C+G + C G S++CP
Sbjct: 237 NSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECP 275
Score = 66.1 bits (154), Expect = 4e-10
Identities = 28/53 (52%), Positives = 37/53 (69%)
Query: 558 GVCEKTIQDVVERFWDIIEDININNVLGFLRDNIVGVVVLVTAFIWIPASCVV 610
G CEK +QDV+ERFWD I+ ++IN FL DNIVG V++ + WIP S +V
Sbjct: 358 GKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILV 410
>AF009615-1|AAC51766.1| 748|Homo sapiens ADAM10 protein.
Length = 748
Score = 220 bits (537), Expect = 1e-56
Identities = 173/535 (32%), Positives = 257/535 (48%), Gaps = 71/535 (13%)
Query: 39 FKTLGKDFRLILHPQSSVLHSNFKAYSVDADGKETTVHVDRENFFTGRVFGETKSDVKLH 98
F G+ F L + +S+ FK V+ K + D + +TG ++GE S
Sbjct: 64 FHAHGRHFNLRMKRDTSLFSDEFK---VETSNK--VLDYDTSHIYTGHIYGEEGSFSHGS 118
Query: 99 MEDGVMTGIIHTPDETYHVEPSWRHLPD--LDGKSMITYRSSDIRYSWAGDAIPNKPRVC 156
+ DG G I T T++VEP+ R++ D L S+I Y DI Y P+K
Sbjct: 119 VIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVI-YHEDDINY-------PHK---- 166
Query: 157 GYVKEGKELEDDSDDVQEEYDIELKHEQLEKEKYLDQTNSYHPANEADTSNDGPKKRTKR 216
Y +G D S ++ K++ E+ H AN GP+ K+
Sbjct: 167 -YGPQGG-CADHS-----VFERMRKYQMTGVEEVTQIPQEEHAAN-------GPELLRKK 212
Query: 217 QSDYEYTPTKTRCPLLLVADYRFFQEMGASNTKTTISYLISLIDRVHKIYNDTLWQDRQD 276
++ + K C L + D+ FF+ G + I+ + S + + IY T D
Sbjct: 213 RTT---SAEKNTCQLYIQTDHLFFKYYGTR--EAVIAQISSHVKAIDTIYQTT------D 261
Query: 277 MDGFKGMGFVIKKILVHSEPTRVRGGEAHYNMVR-EKWDVRNLLEVFSREYSHKDFCLAH 335
G + + F++K+I +++ + N R V LE+ S E +H D+CLA+
Sbjct: 262 FSGIRNISFMVKRIRINTTADE----KDPTNPFRFPNIGVEKFLELNS-EQNHDDYCLAY 316
Query: 336 LFTDLKFEGGILGLAYVGSPRRNSVGGICTP-EYFKNGYTLYLNSGLSSSRNHYGQRVIT 394
+FTD F+ G+LGLA+VG+P +S GGIC + + +G LN+G+ + +N YG V
Sbjct: 317 VFTDRDFDDGVLGLAWVGAPSGSS-GGICEKSKLYSDGKKKSLNTGIITVQN-YGSHVPP 374
Query: 395 READLVTAHEFGHNWGSEHDPDVAECSPAAS------QGGSYLMYTYSVSGYDVNNKRFS 448
+ + + AHE GHN+GS HD EC+P S + G+Y+MY + SG +NN +FS
Sbjct: 375 KVSHITFAHEVGHNFGSPHDSGT-ECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFS 433
Query: 449 PCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKN----- 503
CS+R+I +VL+ K CF E + CGN VE GEECD G ++ C D N
Sbjct: 434 LCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGR 493
Query: 504 -CKLRKNQGAVCSDKNSPCC-AGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
CKL+ G CS PCC A C F CR+ S C E ICNG +A CP
Sbjct: 494 KCKLK--PGKQCSPSQGPCCTAQCAFKSKSEKCRD--DSDCAREGICNGFTALCP 544
>Z48579-1|CAA88463.1| 691|Homo sapiens disintegrin-metalloprotease
MADM protein.
Length = 691
Score = 201 bits (491), Expect = 5e-51
Identities = 130/364 (35%), Positives = 190/364 (52%), Gaps = 38/364 (10%)
Query: 208 DGPKKRTKRQSDYEYTPTKTRCPLLLVADYRFFQEMGASNTKTTISYLISLIDRVHKIYN 267
+GP+ KR++ + K C L + D+ FF+ G + I+ + S + + IY
Sbjct: 147 NGPELLRKRRTT---SAEKNTCQLYIQTDHLFFKYYGTR--EAVIAQISSHVKAIDTIYQ 201
Query: 268 DTLWQDRQDMDGFKGMGFVIKKILVHSEPTRVRGGEAHYNMVR-EKWDVRNLLEVFSREY 326
T D G + + F++K+I +++ + N R V LE+ S E
Sbjct: 202 TT------DFSGIRNISFMVKRIRINTTADE----KDPTNPFRFPNISVEKFLELNS-EQ 250
Query: 327 SHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTP-EYFKNGYTLYLNSGLSSSR 385
+H D+CLA++FTD F+ G+LGLA+VG+P +S GGIC + + +G LN+G+ + +
Sbjct: 251 NHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSS-GGICEKSKLYSDGKKKSLNTGIITVQ 309
Query: 386 NHYGQRVITREADLVTAHEFGHNWGSEHDPDVAECSPAAS------QGGSYLMYTYSVSG 439
N YG V + + + AHE GHN+GS HD EC+P S + G+Y+MY + SG
Sbjct: 310 N-YGSHVPPKVSHITFAHEVGHNFGSPHDSGT-ECTPGESKNLGQKENGNYIMYARATSG 367
Query: 440 YDVNNKRFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMC 499
+NN +FS CS+R+I +VL+ K CF E + CGN VE GEECD G ++ C
Sbjct: 368 DKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECC 427
Query: 500 CDKN------CKLRKNQGAVCSDKNSPCC-AGCVFAPPGLVCREAAHSACEGEAICNGAS 552
D N CKL+ G CS PCC A C F CR+ S C E ICNG +
Sbjct: 428 FDANQPEGRKCKLK--PGKQCSPSQGPCCTAQCAFKSKSEKCRD--DSDCAREGICNGFT 483
Query: 553 ADCP 556
A CP
Sbjct: 484 ALCP 487
>BC126253-1|AAI26254.1| 512|Homo sapiens ADAM10 protein protein.
Length = 512
Score = 189 bits (461), Expect = 2e-47
Identities = 155/500 (31%), Positives = 239/500 (47%), Gaps = 67/500 (13%)
Query: 39 FKTLGKDFRLILHPQSSVLHSNFKAYSVDADGKETTVHVDRENFFTGRVFGETKSDVKLH 98
F G+ F L + +S+ FK V+ K + D + +TG ++GE S
Sbjct: 64 FHAHGRHFNLRMKRDTSLFSDEFK---VETSNK--VLDYDTSHIYTGHIYGEEGSFSHGS 118
Query: 99 MEDGVMTGIIHTPDETYHVEPSWRHLPD--LDGKSMITYRSSDIRYSWAGDAIPNKPRVC 156
+ DG G I T T++VEP+ R++ D L S+I Y DI Y P+K
Sbjct: 119 VIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVI-YHEDDINY-------PHK---- 166
Query: 157 GYVKEGKELEDDSDDVQEEYDIELKHEQLEKEKYLDQTNSYHPANEADTSNDGPKKRTKR 216
Y +G D S ++ K++ E+ H AN GP+ K+
Sbjct: 167 -YGPQGG-CADHS-----VFERMRKYQMTGVEEVTQIPQEEHAAN-------GPELLRKK 212
Query: 217 QSDYEYTPTKTRCPLLLVADYRFFQEMGASNTKTTISYLISLIDRVHKIYNDTLWQDRQD 276
++ + K C L + D+ FF+ G + I+ + S + + IY T D
Sbjct: 213 RTT---SAEKNTCQLYIQTDHLFFKYYGTR--EAVIAQISSHVKAIDTIYQTT------D 261
Query: 277 MDGFKGMGFVIKKILVHSEPTRVRGGEAHYNMVR-EKWDVRNLLEVFSREYSHKDFCLAH 335
G + + F++K+I +++ + N R V LE+ S E +H D+CLA+
Sbjct: 262 FSGIRNISFMVKRIRINTTADE----KDPTNPFRFPNIGVEKFLELNS-EQNHDDYCLAY 316
Query: 336 LFTDLKFEGGILGLAYVGSPRRNSVGGICTP-EYFKNGYTLYLNSGLSSSRNHYGQRVIT 394
+FTD F+ G+LGLA+VG+P +S GGIC + + +G LN+G+ + +N YG V
Sbjct: 317 VFTDRDFDDGVLGLAWVGAPSGSS-GGICEKSKLYSDGKKKSLNTGIITVQN-YGSHVPP 374
Query: 395 READLVTAHEFGHNWGSEHDPDVAECSPAAS------QGGSYLMYTYSVSGYDVNNKRFS 448
+ + + AHE GHN+GS HD EC+P S + G+Y+MY + SG +NN +FS
Sbjct: 375 KVSHITFAHEVGHNFGSPHDSGT-ECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFS 433
Query: 449 PCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKNC-KLR 507
CS+R+I +VL+ K CF E + CGN VE GEECD G +D C D+ C
Sbjct: 434 LCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGY-----SDQCKDECCFDAN 488
Query: 508 KNQGAVCSDK-NSPCCAGCV 526
+ +G C K C C+
Sbjct: 489 QPEGRKCKLKPGKQCSTVCI 508
>DQ995342-1|ABI97387.1| 813|Homo sapiens ADAM metallopeptidase
domain 33 protein.
Length = 813
Score = 101 bits (242), Expect = 8e-21
Identities = 63/166 (37%), Positives = 83/166 (50%), Gaps = 18/166 (10%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH+ G HDPD C AA++ G +M + +G+ + FS CS R +R +
Sbjct: 344 AHEIGHSLGLSHDPDGC-CVEAAAESGGCVM--AAATGHPF-PRVFSACSRRQLRAFFRK 399
Query: 462 KSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCC-DKNCKLRKNQGAV 513
G C S + + CGN VE GEECD G G E D+CC NC LR GA
Sbjct: 400 GGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCG-PGQECRDLCCFAHNCSLR--PGAQ 456
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + CC C+ P G +CR+A C+ C G S+ CP V
Sbjct: 457 CA--HGDCCVRCLLKPAGALCRQAM-GDCDLPEFCTGTSSHCPPDV 499
>AY358314-1|AAQ88680.1| 813|Homo sapiens Adam33 protein.
Length = 813
Score = 101 bits (242), Expect = 8e-21
Identities = 63/166 (37%), Positives = 83/166 (50%), Gaps = 18/166 (10%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH+ G HDPD C AA++ G +M + +G+ + FS CS R +R +
Sbjct: 344 AHEIGHSLGLSHDPDGC-CVEAAAESGGCVM--AAATGHPF-PRVFSACSRRQLRAFFRK 399
Query: 462 KSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCC-DKNCKLRKNQGAV 513
G C S + + CGN VE GEECD G G E D+CC NC LR GA
Sbjct: 400 GGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCG-PGQECRDLCCFAHNCSLR--PGAQ 456
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + CC C+ P G +CR+A C+ C G S+ CP V
Sbjct: 457 CA--HGDCCVRCLLKPAGALCRQAM-GDCDLPEFCTGTSSHCPPDV 499
>AL356755-2|CAI23465.1| 813|Homo sapiens ADAM metallopeptidase
domain 33 protein.
Length = 813
Score = 101 bits (242), Expect = 8e-21
Identities = 63/166 (37%), Positives = 83/166 (50%), Gaps = 18/166 (10%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH+ G HDPD C AA++ G +M + +G+ + FS CS R +R +
Sbjct: 344 AHEIGHSLGLSHDPDGC-CVEAAAESGGCVM--AAATGHPF-PRVFSACSRRQLRAFFRK 399
Query: 462 KSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCC-DKNCKLRKNQGAV 513
G C S + + CGN VE GEECD G G E D+CC NC LR GA
Sbjct: 400 GGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCG-PGQECRDLCCFAHNCSLR--PGAQ 456
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + CC C+ P G +CR+A C+ C G S+ CP V
Sbjct: 457 CA--HGDCCVRCLLKPAGALCRQAM-GDCDLPEFCTGTSSHCPPDV 499
>AL356755-1|CAM28348.1| 812|Homo sapiens ADAM metallopeptidase
domain 33 protein.
Length = 812
Score = 101 bits (242), Expect = 8e-21
Identities = 63/166 (37%), Positives = 83/166 (50%), Gaps = 18/166 (10%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH+ G HDPD C AA++ G +M + +G+ + FS CS R +R +
Sbjct: 344 AHEIGHSLGLSHDPDGC-CVEAAAESGGCVM--AAATGHPF-PRVFSACSRRQLRAFFRK 399
Query: 462 KSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCC-DKNCKLRKNQGAV 513
G C S + + CGN VE GEECD G G E D+CC NC LR GA
Sbjct: 400 GGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCG-PGQECRDLCCFAHNCSLR--PGAQ 456
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + CC C+ P G +CR+A C+ C G S+ CP V
Sbjct: 457 CA--HGDCCVRCLLKPAGALCRQAM-GDCDLPEFCTGTSSHCPPDV 499
>AL109804-2|CAI18840.1| 813|Homo sapiens ADAM metallopeptidase
domain 33 protein.
Length = 813
Score = 101 bits (242), Expect = 8e-21
Identities = 63/166 (37%), Positives = 83/166 (50%), Gaps = 18/166 (10%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH+ G HDPD C AA++ G +M + +G+ + FS CS R +R +
Sbjct: 344 AHEIGHSLGLSHDPDGC-CVEAAAESGGCVM--AAATGHPF-PRVFSACSRRQLRAFFRK 399
Query: 462 KSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCC-DKNCKLRKNQGAV 513
G C S + + CGN VE GEECD G G E D+CC NC LR GA
Sbjct: 400 GGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCG-PGQECRDLCCFAHNCSLR--PGAQ 456
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + CC C+ P G +CR+A C+ C G S+ CP V
Sbjct: 457 CA--HGDCCVRCLLKPAGALCRQAM-GDCDLPEFCTGTSSHCPPDV 499
>AL109804-1|CAM26955.1| 812|Homo sapiens ADAM metallopeptidase
domain 33 protein.
Length = 812
Score = 101 bits (242), Expect = 8e-21
Identities = 63/166 (37%), Positives = 83/166 (50%), Gaps = 18/166 (10%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH+ G HDPD C AA++ G +M + +G+ + FS CS R +R +
Sbjct: 344 AHEIGHSLGLSHDPDGC-CVEAAAESGGCVM--AAATGHPF-PRVFSACSRRQLRAFFRK 399
Query: 462 KSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCC-DKNCKLRKNQGAV 513
G C S + + CGN VE GEECD G G E D+CC NC LR GA
Sbjct: 400 GGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCG-PGQECRDLCCFAHNCSLR--PGAQ 456
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + CC C+ P G +CR+A C+ C G S+ CP V
Sbjct: 457 CA--HGDCCVRCLLKPAGALCRQAM-GDCDLPEFCTGTSSHCPPDV 499
>AF466288-1|AAM80483.1| 812|Homo sapiens a disintegrin and
metalloprotease domain 33 protein.
Length = 812
Score = 101 bits (242), Expect = 8e-21
Identities = 63/166 (37%), Positives = 83/166 (50%), Gaps = 18/166 (10%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH+ G HDPD C AA++ G +M + +G+ + FS CS R +R +
Sbjct: 344 AHEIGHSLGLSHDPDGC-CVEAAAESGGCVM--AAATGHPF-PRVFSACSRRQLRAFFRK 399
Query: 462 KSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCC-DKNCKLRKNQGAV 513
G C S + + CGN VE GEECD G G E D+CC NC LR GA
Sbjct: 400 GGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCG-PGQECRDLCCFAHNCSLR--PGAQ 456
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + CC C+ P G +CR+A C+ C G S+ CP V
Sbjct: 457 CA--HGDCCVRCLLKPAGALCRQAM-GDCDLPEFCTGTSSHCPPDV 499
>AF466287-1|AAM80482.1| 812|Homo sapiens a disintegrin and
metalloprotease domain 33 protein.
Length = 812
Score = 101 bits (242), Expect = 8e-21
Identities = 63/166 (37%), Positives = 83/166 (50%), Gaps = 18/166 (10%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH+ G HDPD C AA++ G +M + +G+ + FS CS R +R +
Sbjct: 344 AHEIGHSLGLSHDPDGC-CVEAAAESGGCVM--AAATGHPF-PRVFSACSRRQLRAFFRK 399
Query: 462 KSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCC-DKNCKLRKNQGAV 513
G C S + + CGN VE GEECD G G E D+CC NC LR GA
Sbjct: 400 GGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCG-PGQECRDLCCFAHNCSLR--PGAQ 456
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + CC C+ P G +CR+A C+ C G S+ CP V
Sbjct: 457 CA--HGDCCVRCLLKPAGALCRQAM-GDCDLPEFCTGTSSHCPPDV 499
>AB055891-1|BAB83092.1| 813|Homo sapiens metalloprotease
disintegrin protein.
Length = 813
Score = 101 bits (242), Expect = 8e-21
Identities = 63/166 (37%), Positives = 83/166 (50%), Gaps = 18/166 (10%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH+ G HDPD C AA++ G +M + +G+ + FS CS R +R +
Sbjct: 344 AHEIGHSLGLSHDPDGC-CVEAAAESGGCVM--AAATGHPF-PRVFSACSRRQLRAFFRK 399
Query: 462 KSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCC-DKNCKLRKNQGAV 513
G C S + + CGN VE GEECD G G E D+CC NC LR GA
Sbjct: 400 GGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCG-PGQECRDLCCFAHNCSLR--PGAQ 456
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + CC C+ P G +CR+A C+ C G S+ CP V
Sbjct: 457 CA--HGDCCVRCLLKPAGALCRQAM-GDCDLPEFCTGTSSHCPPDV 499
>Y13786-1|CAC20585.1| 918|Homo sapiens meltrin-beta/ADAM 19
homologue protein.
Length = 918
Score = 93.1 bits (221), Expect = 3e-18
Identities = 61/163 (37%), Positives = 82/163 (50%), Gaps = 19/163 (11%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN+G HD A+C A++ G +M + +G+ K F+ C+ R + + LQ+
Sbjct: 344 AHEMGHNFGMTHDS--ADCCSASAADGGCIMA--AATGHPFP-KVFNGCNRRELDRYLQS 398
Query: 462 KSGRCFSE-PEESF------CGNLRVEGGEECDAGLLGTEDNDMCCD-KNCKLRKNQGAV 513
G C S P+ CGN +E GEECD G E N+ CC+ NC LR GA
Sbjct: 399 GGGMCLSNMPDTRMLYGGRRCGNGYLEDGEECDCG-EEEECNNPCCNASNCTLR--PGAE 455
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
C+ + CC C PG +CRE A C+ C G S CP
Sbjct: 456 CA--HGSCCHQCKLLAPGTLCREQARQ-CDLPEFCTGKSPHCP 495
>AF311317-1|AAK07852.1| 918|Homo sapiens disintegrin and
metalloproteinase ADAM19 protein.
Length = 918
Score = 93.1 bits (221), Expect = 3e-18
Identities = 61/163 (37%), Positives = 82/163 (50%), Gaps = 19/163 (11%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN+G HD A+C A++ G +M + +G+ K F+ C+ R + + LQ+
Sbjct: 344 AHEMGHNFGMTHDS--ADCCSASAADGGCIMA--AATGHPFP-KVFNGCNRRELDRYLQS 398
Query: 462 KSGRCFSE-PEESF------CGNLRVEGGEECDAGLLGTEDNDMCCD-KNCKLRKNQGAV 513
G C S P+ CGN +E GEECD G E N+ CC+ NC LR GA
Sbjct: 399 GGGMCLSNMPDTRMLYGGRRCGNGYLEDGEECDCG-EEEECNNPCCNASNCTLR--PGAE 455
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
C+ + CC C PG +CRE A C+ C G S CP
Sbjct: 456 CA--HGSCCHQCKLLAPGTLCREQARQ-CDLPEFCTGKSPHCP 495
>AF134707-1|AAF22162.1| 857|Homo sapiens disintegrin and
metalloproteinase domain 19 protein.
Length = 857
Score = 93.1 bits (221), Expect = 3e-18
Identities = 61/163 (37%), Positives = 82/163 (50%), Gaps = 19/163 (11%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN+G HD A+C A++ G +M + +G+ K F+ C+ R + + LQ+
Sbjct: 246 AHEMGHNFGMTHDS--ADCCSASAADGGCIMA--AATGHPFP-KVFNGCNRRELDRYLQS 300
Query: 462 KSGRCFSE-PEESF------CGNLRVEGGEECDAGLLGTEDNDMCCD-KNCKLRKNQGAV 513
G C S P+ CGN +E GEECD G E N+ CC+ NC LR GA
Sbjct: 301 GGGMCLSNMPDTRMLYGGRRCGNGYLEDGEECDCG-EEEECNNPCCNASNCTLR--PGAE 357
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
C+ + CC C PG +CRE A C+ C G S CP
Sbjct: 358 CA--HGSCCHQCKLLAPGTLCREQARQ-CDLPEFCTGKSPHCP 397
>U46005-1|AAC51112.1| 814|Homo sapiens MDC15 protein.
Length = 814
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>U41767-1|AAC50404.1| 814|Homo sapiens metargidin precursor
protein.
Length = 814
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>U41766-1|AAC50403.1| 819|Homo sapiens
metalloprotease/disintegrin/cysteine-rich protein
precursor protein.
Length = 819
Score = 91.9 bits (218), Expect = 6e-18
Identities = 65/182 (35%), Positives = 85/182 (46%), Gaps = 23/182 (12%)
Query: 386 NHYGQRVITREADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNK 445
N +GQ + A +V AHE GHN G HD D +CS A S +M + SG ++
Sbjct: 331 NVFGQITVETFASIV-AHELGHNLGMNHD-DGRDCSCGAK---SCIMNS-GASG----SR 380
Query: 446 RFSPCSLRSIRKVLQAKSGRCF---SEPEESF----CGNLRVEGGEECDAGLLGTEDNDM 498
FS CS K+ K G C +P+E++ CGN V+ GEECD G + D
Sbjct: 381 NFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNKLVDAGEECDCGTPKECELDP 440
Query: 499 CCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPK 557
CC+ CKL+ D CC C F P G +CR S C+ CNG+S C
Sbjct: 441 CCEGSTCKLKSFAECAYGD----CCKDCRFLPGGTLCR-GKTSECDVPEYCNGSSQFCQP 495
Query: 558 GV 559
V
Sbjct: 496 DV 497
Score = 34.3 bits (75), Expect = 1.4
Identities = 35/147 (23%), Positives = 60/147 (40%), Gaps = 16/147 (10%)
Query: 30 PYNTIKEVRFKTLGKDFRLILHPQSSVLHSNFKAYSVDADGKETTVHVDREN--FFTGRV 87
PY+ + GK+ + L +L +F Y+ + +G T H + +N + G V
Sbjct: 61 PYSKQVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDHPNIQNHCHYRGYV 120
Query: 88 FGETKSDVKLHMEDGVMTGIIHTPDETYHVEPSWRHLPDLDGKSMITYRSSDIRYSWAGD 147
G S + L G + G++H + +Y +EP L + I YR D+
Sbjct: 121 EGVHNSSIALSDCFG-LRGLLHLENASYGIEP----LQNSSHFEHIIYRMDDVY------ 169
Query: 148 AIPNKPRVCGYVKEGKELEDDSDDVQE 174
+P CG + E E D+ +E
Sbjct: 170 ---KEPLKCGVSNKDIEKETAKDEEEE 193
>D14665-1|BAA03499.2| 703|Homo sapiens KIAA0021 protein protein.
Length = 703
Score = 91.9 bits (218), Expect = 6e-18
Identities = 65/182 (35%), Positives = 85/182 (46%), Gaps = 23/182 (12%)
Query: 386 NHYGQRVITREADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNK 445
N +GQ + A +V AHE GHN G HD D +CS A S +M + SG ++
Sbjct: 215 NVFGQITVETFASIV-AHELGHNLGMNHD-DGRDCSCGAK---SCIMNS-GASG----SR 264
Query: 446 RFSPCSLRSIRKVLQAKSGRCF---SEPEESF----CGNLRVEGGEECDAGLLGTEDNDM 498
FS CS K+ K G C +P+E++ CGN V+ GEECD G + D
Sbjct: 265 NFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNKLVDAGEECDCGTPKECELDP 324
Query: 499 CCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPK 557
CC+ CKL+ D CC C F P G +CR S C+ CNG+S C
Sbjct: 325 CCEGSTCKLKSFAECAYGD----CCKDCRFLPGGTLCR-GKTSECDVPEYCNGSSQFCQP 379
Query: 558 GV 559
V
Sbjct: 380 DV 381
>BT009764-1|AAP88766.1| 814|Homo sapiens a disintegrin and
metalloproteinase domain 15 (metargidin) protein.
Length = 814
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>BC126406-1|AAI26407.1| 712|Homo sapiens ADAM9 protein protein.
Length = 712
Score = 91.9 bits (218), Expect = 6e-18
Identities = 65/182 (35%), Positives = 85/182 (46%), Gaps = 23/182 (12%)
Query: 386 NHYGQRVITREADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNK 445
N +GQ + A +V AHE GHN G HD D +CS A S +M + SG ++
Sbjct: 331 NVFGQITVETFASIV-AHELGHNLGMNHD-DGRDCSCGAK---SCIMNS-GASG----SR 380
Query: 446 RFSPCSLRSIRKVLQAKSGRCF---SEPEESF----CGNLRVEGGEECDAGLLGTEDNDM 498
FS CS K+ K G C +P+E++ CGN V+ GEECD G + D
Sbjct: 381 NFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNKLVDAGEECDCGTPKECELDP 440
Query: 499 CCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPK 557
CC+ CKL+ D CC C F P G +CR S C+ CNG+S C
Sbjct: 441 CCEGSTCKLKSFAECAYGD----CCKDCRFLPGGTLCR-GKTSECDVPEYCNGSSQFCQP 495
Query: 558 GV 559
V
Sbjct: 496 DV 497
Score = 34.3 bits (75), Expect = 1.4
Identities = 35/147 (23%), Positives = 60/147 (40%), Gaps = 16/147 (10%)
Query: 30 PYNTIKEVRFKTLGKDFRLILHPQSSVLHSNFKAYSVDADGKETTVHVDREN--FFTGRV 87
PY+ + GK+ + L +L +F Y+ + +G T H + +N + G V
Sbjct: 61 PYSKQVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDHPNIQNHCHYRGYV 120
Query: 88 FGETKSDVKLHMEDGVMTGIIHTPDETYHVEPSWRHLPDLDGKSMITYRSSDIRYSWAGD 147
G S + L G + G++H + +Y +EP L + I YR D+
Sbjct: 121 EGVHNSSIALSDCFG-LRGLLHLENASYGIEP----LQNSSHFEHIIYRMDDVY------ 169
Query: 148 AIPNKPRVCGYVKEGKELEDDSDDVQE 174
+P CG + E E D+ +E
Sbjct: 170 ---KEPLKCGVSNKDIEKETAKDEEEE 193
>BC014566-1|AAH14566.1| 814|Homo sapiens ADAM metallopeptidase
domain 15 (metargidin) protein.
Length = 814
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY576417-1|AAS73000.1| 797|Homo sapiens ADAM15 isoform 8 protein.
Length = 797
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY560601-1|AAS72999.1| 822|Homo sapiens ADAM15 isoform 7b protein.
Length = 822
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY560600-1|AAS72998.1| 821|Homo sapiens ADAM15 isoform 7a protein.
Length = 821
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY560599-1|AAS72997.1| 863|Homo sapiens ADAM15 isoform 6b protein.
Length = 863
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY560598-1|AAS72996.1| 862|Homo sapiens ADAM15 isoform 6a protein.
Length = 862
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY560597-1|AAS72995.1| 838|Homo sapiens ADAM15 isoform 5 protein.
Length = 838
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY560596-1|AAS72994.1| 839|Homo sapiens ADAM15 isoform 4a protein.
Length = 839
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY560595-1|AAS72993.1| 796|Homo sapiens ADAM15 isoform 3a protein.
Length = 796
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY560594-1|AAS72992.1| 814|Homo sapiens ADAM15 isoform 2 protein.
Length = 814
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY560593-1|AAS72991.1| 772|Homo sapiens ADAM15 isoform 1 protein.
Length = 772
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AY518542-1|AAR99331.1| 772|Homo sapiens ADAM-15 precursor protein.
Length = 772
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AL691442-13|CAI15327.1| 814|Homo sapiens ADAM metallopeptidase
domain 15 (metargidin) protein.
Length = 814
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AL451085-35|CAI13274.1| 814|Homo sapiens ADAM metallopeptidase
domain 15 (metargidin) protein.
Length = 814
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AF495383-1|AAM49575.1| 655|Homo sapiens
disintegrin/metalloproteinase domain 9 short protein
precursor protein.
Length = 655
Score = 91.9 bits (218), Expect = 6e-18
Identities = 65/182 (35%), Positives = 85/182 (46%), Gaps = 23/182 (12%)
Query: 386 NHYGQRVITREADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNK 445
N +GQ + A +V AHE GHN G HD D +CS A S +M + SG ++
Sbjct: 331 NVFGQITVETFASIV-AHELGHNLGMNHD-DGRDCSCGAK---SCIMNS-GASG----SR 380
Query: 446 RFSPCSLRSIRKVLQAKSGRCF---SEPEESF----CGNLRVEGGEECDAGLLGTEDNDM 498
FS CS K+ K G C +P+E++ CGN V+ GEECD G + D
Sbjct: 381 NFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNKLVDAGEECDCGTPKECELDP 440
Query: 499 CCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPK 557
CC+ CKL+ D CC C F P G +CR S C+ CNG+S C
Sbjct: 441 CCEGSTCKLKSFAECAYGD----CCKDCRFLPGGTLCR-GKTSECDVPEYCNGSSQFCQP 495
Query: 558 GV 559
V
Sbjct: 496 DV 497
Score = 34.3 bits (75), Expect = 1.4
Identities = 35/147 (23%), Positives = 60/147 (40%), Gaps = 16/147 (10%)
Query: 30 PYNTIKEVRFKTLGKDFRLILHPQSSVLHSNFKAYSVDADGKETTVHVDREN--FFTGRV 87
PY+ + GK+ + L +L +F Y+ + +G T H + +N + G V
Sbjct: 61 PYSKQVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDHPNIQNHCHYRGYV 120
Query: 88 FGETKSDVKLHMEDGVMTGIIHTPDETYHVEPSWRHLPDLDGKSMITYRSSDIRYSWAGD 147
G S + L G + G++H + +Y +EP L + I YR D+
Sbjct: 121 EGVHNSSIALSDCFG-LRGLLHLENASYGIEP----LQNSSHFEHIIYRMDDVY------ 169
Query: 148 AIPNKPRVCGYVKEGKELEDDSDDVQE 174
+P CG + E E D+ +E
Sbjct: 170 ---KEPLKCGVSNKDIEKETAKDEEEE 193
>AF314227-11|AAS72298.1| 797|Homo sapiens ADAM15 isoform 8 protein.
Length = 797
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AF314227-10|AAS48596.1| 821|Homo sapiens ADAM15 isoform 7a
protein.
Length = 821
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AF314227-9|AAS48597.1| 822|Homo sapiens ADAM15 isoform 7b protein.
Length = 822
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AF314227-8|AAS48590.1| 772|Homo sapiens ADAM15 isoform 1 protein.
Length = 772
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AF314227-7|AAS48591.1| 796|Homo sapiens ADAM15 isoform 3a protein.
Length = 796
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AF314227-6|AAM44189.1| 814|Homo sapiens ADAM15 isoform 2 protein.
Length = 814
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AF314227-5|AAS48593.1| 838|Homo sapiens ADAM15 isoform 5 protein.
Length = 838
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AF314227-4|AAS48594.1| 862|Homo sapiens ADAM15 isoform 6a protein.
Length = 862
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AF314227-3|AAS48592.1| 839|Homo sapiens ADAM15 isoform 4a protein.
Length = 839
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AF314227-2|AAS48595.1| 863|Homo sapiens ADAM15 isoform 6b protein.
Length = 863
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 347 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 403
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 404 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 460
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 461 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 504
>AB209157-1|BAD92394.1| 859|Homo sapiens ADAM15 isoform 6a variant
protein.
Length = 859
Score = 91.9 bits (218), Expect = 6e-18
Identities = 60/166 (36%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GH+ G +HD C P + + +M S + FS CS R++ K L
Sbjct: 344 AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIM---EASTDFLPGLNFSNCSRRALEKALL 400
Query: 461 AKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLRKNQGAV 513
G C E P +FCGN+ VE GE+CD G L + D CCD C+LR GA
Sbjct: 401 DGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCDSLTCQLR--PGAQ 457
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 458 CA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 501
>BC060804-1|AAH60804.1| 737|Homo sapiens ADAM metallopeptidase
domain 12 (meltrin alpha) protein.
Length = 737
Score = 88.6 bits (210), Expect = 6e-17
Identities = 63/172 (36%), Positives = 82/172 (47%), Gaps = 18/172 (10%)
Query: 397 ADLVTAHEFGHNWGSEHD--PDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRS 454
A + AHE GHN+G HD C A +GG + + +GY FS CS +
Sbjct: 341 AAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIM---NASTGYPF-PMVFSSCSRKD 396
Query: 455 IRKVLQAKSGRC-FSEPE--ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLR 507
+ L+ G C F+ PE ESF CGN VE GEECD G N C C L+
Sbjct: 397 LETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLK 456
Query: 508 KNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
+ AVC+ + CC C P G CR++++S C+ C GAS CP V
Sbjct: 457 PD--AVCA--HGLCCEDCQLKPAGTACRDSSNS-CDLPEFCTGASPHCPANV 503
>AY358878-1|AAQ89237.1| 735|Homo sapiens ADAM-12 protein.
Length = 735
Score = 88.6 bits (210), Expect = 6e-17
Identities = 63/172 (36%), Positives = 82/172 (47%), Gaps = 18/172 (10%)
Query: 397 ADLVTAHEFGHNWGSEHD--PDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRS 454
A + AHE GHN+G HD C A +GG + + +GY FS CS +
Sbjct: 341 AAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIM---NASTGYPF-PMVFSSCSRKD 396
Query: 455 IRKVLQAKSGRC-FSEPE--ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLR 507
+ L+ G C F+ PE ESF CGN VE GEECD G N C C L+
Sbjct: 397 LETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLK 456
Query: 508 KNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
+ AVC+ + CC C P G CR++++S C+ C GAS CP V
Sbjct: 457 PD--AVCA--HGLCCEDCQLKPAGTACRDSSNS-CDLPEFCTGASPHCPANV 503
>AL589787-6|CAI40683.1| 738|Homo sapiens ADAM metallopeptidase
domain 12 (meltrin alpha) protein.
Length = 738
Score = 88.6 bits (210), Expect = 6e-17
Identities = 63/172 (36%), Positives = 82/172 (47%), Gaps = 18/172 (10%)
Query: 397 ADLVTAHEFGHNWGSEHD--PDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRS 454
A + AHE GHN+G HD C A +GG + + +GY FS CS +
Sbjct: 344 AAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIM---NASTGYPF-PMVFSSCSRKD 399
Query: 455 IRKVLQAKSGRC-FSEPE--ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLR 507
+ L+ G C F+ PE ESF CGN VE GEECD G N C C L+
Sbjct: 400 LETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLK 459
Query: 508 KNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
+ AVC+ + CC C P G CR++++S C+ C GAS CP V
Sbjct: 460 PD--AVCA--HGLCCEDCQLKPAGTACRDSSNS-CDLPEFCTGASPHCPANV 506
>AL589787-5|CAI40682.1| 909|Homo sapiens ADAM metallopeptidase
domain 12 (meltrin alpha) protein.
Length = 909
Score = 88.6 bits (210), Expect = 6e-17
Identities = 63/172 (36%), Positives = 82/172 (47%), Gaps = 18/172 (10%)
Query: 397 ADLVTAHEFGHNWGSEHD--PDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRS 454
A + AHE GHN+G HD C A +GG + + +GY FS CS +
Sbjct: 344 AAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIM---NASTGYPF-PMVFSSCSRKD 399
Query: 455 IRKVLQAKSGRC-FSEPE--ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLR 507
+ L+ G C F+ PE ESF CGN VE GEECD G N C C L+
Sbjct: 400 LETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLK 459
Query: 508 KNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
+ AVC+ + CC C P G CR++++S C+ C GAS CP V
Sbjct: 460 PD--AVCA--HGLCCEDCQLKPAGTACRDSSNS-CDLPEFCTGASPHCPANV 506
>AF023477-1|AAC08703.2| 738|Homo sapiens meltrin-S protein.
Length = 738
Score = 88.6 bits (210), Expect = 6e-17
Identities = 63/172 (36%), Positives = 82/172 (47%), Gaps = 18/172 (10%)
Query: 397 ADLVTAHEFGHNWGSEHD--PDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRS 454
A + AHE GHN+G HD C A +GG + + +GY FS CS +
Sbjct: 344 AAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIM---NASTGYPF-PMVFSSCSRKD 399
Query: 455 IRKVLQAKSGRC-FSEPE--ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLR 507
+ L+ G C F+ PE ESF CGN VE GEECD G N C C L+
Sbjct: 400 LETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLK 459
Query: 508 KNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
+ AVC+ + CC C P G CR++++S C+ C GAS CP V
Sbjct: 460 PD--AVCA--HGLCCEDCQLKPAGTACRDSSNS-CDLPEFCTGASPHCPANV 506
>AF023476-1|AAC08702.2| 909|Homo sapiens meltrin-L precursor
protein.
Length = 909
Score = 88.6 bits (210), Expect = 6e-17
Identities = 63/172 (36%), Positives = 82/172 (47%), Gaps = 18/172 (10%)
Query: 397 ADLVTAHEFGHNWGSEHD--PDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRS 454
A + AHE GHN+G HD C A +GG + + +GY FS CS +
Sbjct: 344 AAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIM---NASTGYPF-PMVFSSCSRKD 399
Query: 455 IRKVLQAKSGRC-FSEPE--ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLR 507
+ L+ G C F+ PE ESF CGN VE GEECD G N C C L+
Sbjct: 400 LETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLK 459
Query: 508 KNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
+ AVC+ + CC C P G CR++++S C+ C GAS CP V
Sbjct: 460 PD--AVCA--HGLCCEDCQLKPAGTACRDSSNS-CDLPEFCTGASPHCPANV 506
>BC132765-1|AAI32766.1| 832|Homo sapiens ADAM metallopeptidase
domain 23 protein.
Length = 832
Score = 86.2 bits (204), Expect = 3e-16
Identities = 64/180 (35%), Positives = 84/180 (46%), Gaps = 24/180 (13%)
Query: 386 NHYGQRVITREADLVTAHEFGHNWGSEHDPDVAE--CSPAASQGGSYLMYTYSVSGYDVN 443
N YG + + V + N G + +P + C S GG + T VS +
Sbjct: 417 NEYGLPMAVAQ---VLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEET-GVS----H 468
Query: 444 NKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLGTEDNDM 498
+++FS CS+ R LQ G C F+ P + F CGN VE GEECD G E +
Sbjct: 469 SRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCG-FHVECYGL 527
Query: 499 CCDKNCKLRKNQGAVCSDKNSPCC--AGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
CC K C L + GA CSD PCC C+F P G CR+A + C+ C G S CP
Sbjct: 528 CC-KKCSL--SNGAHCSD--GPCCNNTSCLFQPRGYECRDAVNE-CDITEYCTGDSGQCP 581
>BC132763-1|AAI32764.1| 832|Homo sapiens ADAM metallopeptidase
domain 23 protein.
Length = 832
Score = 86.2 bits (204), Expect = 3e-16
Identities = 64/180 (35%), Positives = 84/180 (46%), Gaps = 24/180 (13%)
Query: 386 NHYGQRVITREADLVTAHEFGHNWGSEHDPDVAE--CSPAASQGGSYLMYTYSVSGYDVN 443
N YG + + V + N G + +P + C S GG + T VS +
Sbjct: 417 NEYGLPMAVAQ---VLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEET-GVS----H 468
Query: 444 NKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLGTEDNDM 498
+++FS CS+ R LQ G C F+ P + F CGN VE GEECD G E +
Sbjct: 469 SRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCG-FHVECYGL 527
Query: 499 CCDKNCKLRKNQGAVCSDKNSPCC--AGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
CC K C L + GA CSD PCC C+F P G CR+A + C+ C G S CP
Sbjct: 528 CC-KKCSL--SNGAHCSD--GPCCNNTSCLFQPRGYECRDAVNE-CDITEYCTGDSGQCP 581
>AJ005580-1|CAC20565.1| 832|Homo sapiens Adam23 protein protein.
Length = 832
Score = 86.2 bits (204), Expect = 3e-16
Identities = 64/180 (35%), Positives = 84/180 (46%), Gaps = 24/180 (13%)
Query: 386 NHYGQRVITREADLVTAHEFGHNWGSEHDPDVAE--CSPAASQGGSYLMYTYSVSGYDVN 443
N YG + + V + N G + +P + C S GG + T VS +
Sbjct: 417 NEYGLPMAVAQ---VLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEET-GVS----H 468
Query: 444 NKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLGTEDNDM 498
+++FS CS+ R LQ G C F+ P + F CGN VE GEECD G E +
Sbjct: 469 SRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCG-FHVECYGL 527
Query: 499 CCDKNCKLRKNQGAVCSDKNSPCC--AGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
CC K C L + GA CSD PCC C+F P G CR+A + C+ C G S CP
Sbjct: 528 CC-KKCSL--SNGAHCSD--GPCCNNTSCLFQPRGYECRDAVNE-CDITEYCTGDSGQCP 581
>AB009672-1|BAA32351.1| 832|Homo sapiens MDC3 protein.
Length = 832
Score = 86.2 bits (204), Expect = 3e-16
Identities = 64/180 (35%), Positives = 84/180 (46%), Gaps = 24/180 (13%)
Query: 386 NHYGQRVITREADLVTAHEFGHNWGSEHDPDVAE--CSPAASQGGSYLMYTYSVSGYDVN 443
N YG + + V + N G + +P + C S GG + T VS +
Sbjct: 417 NEYGLPMAVAQ---VLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEET-GVS----H 468
Query: 444 NKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLGTEDNDM 498
+++FS CS+ R LQ G C F+ P + F CGN VE GEECD G E +
Sbjct: 469 SRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCG-FHVECYGL 527
Query: 499 CCDKNCKLRKNQGAVCSDKNSPCC--AGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
CC K C L + GA CSD PCC C+F P G CR+A + C+ C G S CP
Sbjct: 528 CC-KKCSL--SNGAHCSD--GPCCNNTSCLFQPRGYECRDAVNE-CDITEYCTGDSGQCP 581
>DQ202398-1|ABA43715.1| 465|Homo sapiens ADAM21-like protein
protein.
Length = 465
Score = 81.8 bits (193), Expect = 7e-15
Identities = 57/172 (33%), Positives = 76/172 (44%), Gaps = 26/172 (15%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH G +HD + C +M T+ V ++F+ CS K
Sbjct: 170 AHELGHTLGMQHDEEFCFCGERGC-----IMNTFRVPA-----EKFTNCSYADFMKTT-L 218
Query: 462 KSGRCFSEPE---ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC 514
G C P E F CGN VE E+CD G + + D CC NC LR GA C
Sbjct: 219 NQGSCLQNPPRLGEIFMLKRCGNGVVEREEQCDCGSVQQCEQDACCPLNCTLR--PGAPC 276
Query: 515 SDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGVCEKTIQD 566
+ CC C F P G +CR+ + C+ CNG S CP+ ++ +QD
Sbjct: 277 A--FGLCCKDCKFMPSGELCRQEVNE-CDLPEWCNGTSLQCPE---DRYVQD 322
>AL691442-12|CAI15328.1| 520|Homo sapiens ADAM metallopeptidase
domain 15 (metargidin) protein.
Length = 520
Score = 81.4 bits (192), Expect = 9e-15
Identities = 48/120 (40%), Positives = 59/120 (49%), Gaps = 12/120 (10%)
Query: 447 FSPCSLRSIRKVLQAKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCC 500
FS CS R++ K L G C E P +FCGN+ VE GE+CD G L + D CC
Sbjct: 96 FSNCSRRALEKALLDGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCC 154
Query: 501 DK-NCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
D C+LR GA C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 155 DSLTCQLR--PGAQCA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 210
>AL451085-36|CAI13273.1| 520|Homo sapiens ADAM metallopeptidase
domain 15 (metargidin) protein.
Length = 520
Score = 81.4 bits (192), Expect = 9e-15
Identities = 48/120 (40%), Positives = 59/120 (49%), Gaps = 12/120 (10%)
Query: 447 FSPCSLRSIRKVLQAKSGRCFSE------PEESFCGNLRVEGGEECDAGLLGTEDNDMCC 500
FS CS R++ K L G C E P +FCGN+ VE GE+CD G L + D CC
Sbjct: 96 FSNCSRRALEKALLDGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCC 154
Query: 501 DK-NCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
D C+LR GA C+ + PCC C P G CR C+ C G S+ CP V
Sbjct: 155 DSLTCQLR--PGAQCA-SDGPCCQNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDV 210
>BC109025-1|AAI09026.1| 721|Homo sapiens ADAM21 protein protein.
Length = 721
Score = 80.6 bits (190), Expect = 2e-14
Identities = 57/172 (33%), Positives = 76/172 (44%), Gaps = 26/172 (15%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH G +HD + C +M T+ V ++F+ CS K
Sbjct: 339 AHELGHTLGMQHDEEFCFCGERGC-----IMNTFRVPA-----EKFTNCSYADFMKTT-L 387
Query: 462 KSGRCFSEPE---ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC 514
G C P E F CGN VE E+CD G + + D CC NC LR GA C
Sbjct: 388 NQGSCLHNPPRLGEIFMLKRCGNGVVEREEQCDCGSVQQCEQDACCLLNCTLR--PGAAC 445
Query: 515 SDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGVCEKTIQD 566
+ CC C F P G +CR+ + C+ CNG S CP+ ++ +QD
Sbjct: 446 A--FGLCCKDCKFMPSGELCRQEVNE-CDLPEWCNGTSHQCPE---DRYVQD 491
>BC109024-1|AAI09025.1| 722|Homo sapiens ADAM metallopeptidase
domain 21 protein.
Length = 722
Score = 80.6 bits (190), Expect = 2e-14
Identities = 57/172 (33%), Positives = 76/172 (44%), Gaps = 26/172 (15%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH G +HD + C +M T+ V ++F+ CS K
Sbjct: 340 AHELGHTLGMQHDEEFCFCGERGC-----IMNTFRVPA-----EKFTNCSYADFMKTT-L 388
Query: 462 KSGRCFSEPE---ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC 514
G C P E F CGN VE E+CD G + + D CC NC LR GA C
Sbjct: 389 NQGSCLHNPPRLGEIFMLKRCGNGVVEREEQCDCGSVQQCEQDACCLLNCTLR--PGAAC 446
Query: 515 SDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGVCEKTIQD 566
+ CC C F P G +CR+ + C+ CNG S CP+ ++ +QD
Sbjct: 447 A--FGLCCKDCKFMPSGELCRQEVNE-CDLPEWCNGTSHQCPE---DRYVQD 492
>AF158644-1|AAD55255.1| 722|Homo sapiens
metalloproteinase-disintegrin protein.
Length = 722
Score = 80.6 bits (190), Expect = 2e-14
Identities = 57/172 (33%), Positives = 76/172 (44%), Gaps = 26/172 (15%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH G +HD + C +M T+ V ++F+ CS K
Sbjct: 340 AHELGHTLGMQHDEEFCFCGERGC-----IMNTFRVPA-----EKFTNCSYADFMKTT-L 388
Query: 462 KSGRCFSEPE---ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC 514
G C P E F CGN VE E+CD G + + D CC NC LR GA C
Sbjct: 389 NQGSCLHNPPRLGEIFMLKRCGNGVVEREEQCDCGSVQQCEQDACCLLNCTLR--PGAAC 446
Query: 515 SDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGVCEKTIQD 566
+ CC C F P G +CR+ + C+ CNG S CP+ ++ +QD
Sbjct: 447 A--FGLCCKDCKFMPSGELCRQEVNE-CDLPEWCNGTSHQCPE---DRYVQD 492
>BC025378-1|AAH25378.2| 776|Homo sapiens ADAM metallopeptidase
domain 20 protein.
Length = 776
Score = 80.2 bits (189), Expect = 2e-14
Identities = 58/168 (34%), Positives = 69/168 (41%), Gaps = 23/168 (13%)
Query: 399 LVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKV 458
+ HE GHN G +HD C +M+ Y V K FS CS
Sbjct: 388 ITLGHELGHNLGMQHDTQWCVCELQWC-----IMHAYR----KVTTK-FSNCSYAQYWDS 437
Query: 459 LQAKSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQG 511
SG C P +CGNL VE GEECD G + D CC NC L + G
Sbjct: 438 T-ISSGLCIQPPPYPGNIFRLKYCGNLVVEEGEECDCGTIRQCAKDPCCLLNCTL--HPG 494
Query: 512 AVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
A C+ CC C F P G +CR+ C+ CNG S CP V
Sbjct: 495 AACA--FGICCKDCKFLPSGTLCRQQV-GECDLPEWCNGTSHQCPDDV 539
>AJ242015-1|CAB42085.1| 775|Homo sapiens eMDC II protein protein.
Length = 775
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/163 (33%), Positives = 74/163 (45%), Gaps = 22/163 (13%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN+G HD +C + + ++S Y + FS CS S K +
Sbjct: 338 AHEMGHNFGMFHDDYSCKCP------STICVMDKALSFYIPTD--FSSCSRLSYDKFFED 389
Query: 462 KSGRC-FSEP------EESFCGNLRVEGGEECDAGLLGTEDNDMCCD-KNCKLRKNQGAV 513
K C F+ P CGN VE GE+CD G E ++CCD K CK++
Sbjct: 390 KLSNCLFNAPLPTDIISTPICGNQLVEMGEDCDCG-TSEECTNICCDAKTCKIKATFQCA 448
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ CC C F G+VCR A C+ +CNG S +CP
Sbjct: 449 LGE----CCEKCQFKKAGMVCR-PAKDECDLPEMCNGKSGNCP 486
>AF158643-1|AAD55254.1| 726|Homo sapiens
metalloproteinase-disintegrin protein.
Length = 726
Score = 80.2 bits (189), Expect = 2e-14
Identities = 58/168 (34%), Positives = 69/168 (41%), Gaps = 23/168 (13%)
Query: 399 LVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKV 458
+ HE GHN G +HD C +M+ Y V K FS CS
Sbjct: 338 ITLGHELGHNLGMQHDTQWCVCELQWC-----IMHAYR----KVTTK-FSNCSYAQYWDS 387
Query: 459 LQAKSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQG 511
SG C P +CGNL VE GEECD G + D CC NC L + G
Sbjct: 388 T-ISSGLCIQPPPYPGNIFRLKYCGNLVVEEGEECDCGTIRQCAKDPCCLLNCTL--HPG 444
Query: 512 AVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
A C+ CC C F P G +CR+ C+ CNG S CP V
Sbjct: 445 AACA--FGICCKDCKFLPSGTLCRQQV-GECDLPEWCNGTSHQCPDDV 489
>AF137335-1|AAD25100.1| 540|Homo sapiens metalloprotease
disintegrin cysteine-rich protein, secreted form MDC-Ls
protein.
Length = 540
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/163 (33%), Positives = 74/163 (45%), Gaps = 22/163 (13%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN+G HD +C + + ++S Y + FS CS S K +
Sbjct: 338 AHEMGHNFGMFHDDYSCKCP------STICVMDKALSFYIPTD--FSSCSRLSYDKFFED 389
Query: 462 KSGRC-FSEP------EESFCGNLRVEGGEECDAGLLGTEDNDMCCD-KNCKLRKNQGAV 513
K C F+ P CGN VE GE+CD G E ++CCD K CK++
Sbjct: 390 KLSNCLFNAPLPTDIISTPICGNQLVEMGEDCDCG-TSEECTNICCDAKTCKIKATFQCA 448
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ CC C F G+VCR A C+ +CNG S +CP
Sbjct: 449 LGE----CCEKCQFKKAGMVCR-PAKDECDLPEMCNGKSGNCP 486
>AF137334-1|AAD25099.1| 775|Homo sapiens metalloprotease
disintegrin cysteine-rich protein, transmembrane form
MDC-Lm protein.
Length = 775
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/163 (33%), Positives = 74/163 (45%), Gaps = 22/163 (13%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN+G HD +C + + ++S Y + FS CS S K +
Sbjct: 338 AHEMGHNFGMFHDDYSCKCP------STICVMDKALSFYIPTD--FSSCSRLSYDKFFED 389
Query: 462 KSGRC-FSEP------EESFCGNLRVEGGEECDAGLLGTEDNDMCCD-KNCKLRKNQGAV 513
K C F+ P CGN VE GE+CD G E ++CCD K CK++
Sbjct: 390 KLSNCLFNAPLPTDIISTPICGNQLVEMGEDCDCG-TSEECTNICCDAKTCKIKATFQCA 448
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ CC C F G+VCR A C+ +CNG S +CP
Sbjct: 449 LGE----CCEKCQFKKAGMVCR-PAKDECDLPEMCNGKSGNCP 486
>AF029899-1|AAC52041.1| 726|Homo sapiens ADAM 20 protein.
Length = 726
Score = 80.2 bits (189), Expect = 2e-14
Identities = 58/168 (34%), Positives = 69/168 (41%), Gaps = 23/168 (13%)
Query: 399 LVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKV 458
+ HE GHN G +HD C +M+ Y V K FS CS
Sbjct: 338 ITLGHELGHNLGMQHDTQWCVCELQWC-----IMHAYR----KVTTK-FSNCSYAQYWDS 387
Query: 459 LQAKSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQG 511
SG C P +CGNL VE GEECD G + D CC NC L + G
Sbjct: 388 T-ISSGLCIQPPPYPGNIFRLKYCGNLVVEEGEECDCGTIRQCAKDPCCLLNCTL--HPG 444
Query: 512 AVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
A C+ CC C F P G +CR+ C+ CNG S CP V
Sbjct: 445 AACA--FGICCKDCKFLPSGTLCRQQV-GECDLPEWCNGTSHQCPDDV 489
>AC009225-1|AAX93195.1| 579|Homo sapiens unknown protein.
Length = 579
Score = 79.8 bits (188), Expect = 3e-14
Identities = 62/176 (35%), Positives = 82/176 (46%), Gaps = 24/176 (13%)
Query: 386 NHYGQRVITREADLVTAHEFGHNWGSEHDPDVAE--CSPAASQGGSYLMYTYSVSGYDVN 443
N YG + + V + N G + +P + C S GG + T VS +
Sbjct: 417 NEYGLPMAVAQ---VLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEET-GVS----H 468
Query: 444 NKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLGTEDNDM 498
+++FS CS+ R LQ G C F+ P + F CGN VE GEECD G E +
Sbjct: 469 SRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCG-FHVECYGL 527
Query: 499 CCDKNCKLRKNQGAVCSDKNSPCC--AGCVFAPPGLVCREAAHSACEGEAICNGAS 552
CC K C L + GA CSD PCC C+F P G CR+A + C+ C G S
Sbjct: 528 CC-KKCSL--SNGAHCSD--GPCCNNTSCLFQPRGYECRDAVNE-CDITEYCTGDS 577
>BC062687-1|AAH62687.1| 209|Homo sapiens ADAM17 protein protein.
Length = 209
Score = 79.0 bits (186), Expect = 5e-14
Identities = 51/153 (33%), Positives = 75/153 (49%), Gaps = 8/153 (5%)
Query: 12 ASIQSTGIVKRGAKLSNHPYNTIKEVRFKTLGKDFRLILHPQSSVLHSNFKAYSVDADGK 71
++IQ + KR + S H T+ + F L + F+L L + NFK VD
Sbjct: 48 SNIQQHSVRKRDLQTSTH-VETL--LTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKN- 103
Query: 72 ETTVHVDRENFFTGRVFGETKSDVKLHMEDGVMTGIIHTPDETYHVEPSWRHLPDLDGKS 131
E+ V ++FFTG V GE S V H+ D + I+T Y++EP WR + D K
Sbjct: 104 ESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKR 163
Query: 132 MITYRSSDIRYSWAGDAIPNKPRVCGYVKEGKE 164
M+ Y+S DI+ + P+VCGY+K E
Sbjct: 164 MLVYKSEDIK----NVSRLQSPKVCGYLKVDNE 192
>AF171931-1|AAF03779.1| 787|Homo sapiens
metallaproteinase-disintegrin gama protein.
Length = 787
Score = 78.2 bits (184), Expect = 8e-14
Identities = 68/225 (30%), Positives = 94/225 (41%), Gaps = 36/225 (16%)
Query: 334 AHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGLSSSRNHYGQRVI 393
+HLFT L G+ GL+ +G+ R G+CTP + ++N L +
Sbjct: 286 SHLFTTL----GLRGLSGIGAFR-----GMCTP-HRSCAIVTFMNKTLGTF--------- 326
Query: 394 TREADLVTAHEFGHNWGSEHDPDVAECSP--AASQGGSYLMYTYSVSGYDVNNKRFSPCS 451
+ AH GHN G HD D CS G+ + +S Y F +
Sbjct: 327 ----SIAVAHHLGHNLGMNHDEDTCRCSQPRCIMHEGNPPITKFSNCSYG----DFWEYT 378
Query: 452 LRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQG 511
+ + +L+ + + CGN VE GEECD G L D CC NC L G
Sbjct: 379 VERTKCLLETVHTKDIFNVKR--CGNGVVEEGEECDCGPLKHCAKDPCCLSNCTL--TDG 434
Query: 512 AVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ C+ CC C F P G VCR+ + C+ CNG S CP
Sbjct: 435 STCA--FGLCCKDCKFLPSGKVCRKEVNE-CDLPEWCNGTSHKCP 476
>AF171930-1|AAF03778.1| 766|Homo sapiens
metallaproteinase-disintegrin beta protein.
Length = 766
Score = 78.2 bits (184), Expect = 8e-14
Identities = 68/225 (30%), Positives = 94/225 (41%), Gaps = 36/225 (16%)
Query: 334 AHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGLSSSRNHYGQRVI 393
+HLFT L G+ GL+ +G+ R G+CTP + ++N L +
Sbjct: 286 SHLFTTL----GLRGLSGIGAFR-----GMCTP-HRSCAIVTFMNKTLGTF--------- 326
Query: 394 TREADLVTAHEFGHNWGSEHDPDVAECSP--AASQGGSYLMYTYSVSGYDVNNKRFSPCS 451
+ AH GHN G HD D CS G+ + +S Y F +
Sbjct: 327 ----SIAVAHHLGHNLGMNHDEDTCRCSQPRCIMHEGNPPITKFSNCSYG----DFWEYT 378
Query: 452 LRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQG 511
+ + +L+ + + CGN VE GEECD G L D CC NC L G
Sbjct: 379 VERTKCLLETVHTKDIFNVKR--CGNGVVEEGEECDCGPLKHCAKDPCCLSNCTL--TDG 434
Query: 512 AVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ C+ CC C F P G VCR+ + C+ CNG S CP
Sbjct: 435 STCA--FGLCCKDCKFLPSGKVCRKEVNE-CDLPEWCNGTSHKCP 476
>AF171929-1|AAF03777.1| 820|Homo sapiens
metallaproteinase-disintegrin protein.
Length = 820
Score = 78.2 bits (184), Expect = 8e-14
Identities = 68/225 (30%), Positives = 94/225 (41%), Gaps = 36/225 (16%)
Query: 334 AHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGLSSSRNHYGQRVI 393
+HLFT L G+ GL+ +G+ R G+CTP + ++N L +
Sbjct: 286 SHLFTTL----GLRGLSGIGAFR-----GMCTP-HRSCAIVTFMNKTLGTF--------- 326
Query: 394 TREADLVTAHEFGHNWGSEHDPDVAECSP--AASQGGSYLMYTYSVSGYDVNNKRFSPCS 451
+ AH GHN G HD D CS G+ + +S Y F +
Sbjct: 327 ----SIAVAHHLGHNLGMNHDEDTCRCSQPRCIMHEGNPPITKFSNCSYG----DFWEYT 378
Query: 452 LRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQG 511
+ + +L+ + + CGN VE GEECD G L D CC NC L G
Sbjct: 379 VERTKCLLETVHTKDIFNVKR--CGNGVVEEGEECDCGPLKHCAKDPCCLSNCTL--TDG 434
Query: 512 AVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ C+ CC C F P G VCR+ + C+ CNG S CP
Sbjct: 435 STCA--FGLCCKDCKFLPSGKVCRKEVNE-CDLPEWCNGTSHKCP 476
>AF134708-1|AAF22163.1| 820|Homo sapiens disintegrin and
metalloproteinase domain 29 protein.
Length = 820
Score = 78.2 bits (184), Expect = 8e-14
Identities = 68/225 (30%), Positives = 94/225 (41%), Gaps = 36/225 (16%)
Query: 334 AHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGLSSSRNHYGQRVI 393
+HLFT L G+ GL+ +G+ R G+CTP + ++N L +
Sbjct: 286 SHLFTTL----GLRGLSGIGAFR-----GMCTP-HRSCAIVTFMNKTLGTF--------- 326
Query: 394 TREADLVTAHEFGHNWGSEHDPDVAECSP--AASQGGSYLMYTYSVSGYDVNNKRFSPCS 451
+ AH GHN G HD D CS G+ + +S Y F +
Sbjct: 327 ----SIAVAHHLGHNLGMNHDEDTCRCSQPRCIMHEGNPPITKFSNCSYG----DFWEYT 378
Query: 452 LRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQG 511
+ + +L+ + + CGN VE GEECD G L D CC NC L G
Sbjct: 379 VERTKCLLETVHTKDIFNVKR--CGNGVVEEGEECDCGPLKHCAKDPCCLSNCTL--TDG 434
Query: 512 AVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ C+ CC C F P G VCR+ + C+ CNG S CP
Sbjct: 435 STCA--FGLCCKDCKFLPSGKVCRKEVNE-CDLPEWCNGTSHKCP 476
>AF029900-1|AAC52042.1| 542|Homo sapiens ADAM 21 protein.
Length = 542
Score = 78.2 bits (184), Expect = 8e-14
Identities = 56/172 (32%), Positives = 76/172 (44%), Gaps = 26/172 (15%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE G+ G +HD + C +M T+ V ++F+ CS K
Sbjct: 160 AHELGYTLGMQHDEEFCFCGERGC-----IMNTFRVPA-----EKFTNCSYADFMKTT-L 208
Query: 462 KSGRCFSEPE---ESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC 514
G C P E F CGN VE E+CD G + + D CC NC LR GA C
Sbjct: 209 NQGSCLHNPPRLGEIFMLKRCGNGVVEREEQCDCGSVQQCEQDACCLLNCTLR--PGAAC 266
Query: 515 SDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGVCEKTIQD 566
+ CC C F P G +CR+ + C+ CNG S CP+ ++ +QD
Sbjct: 267 A--FGLCCKDCKFMPSGELCRQEVNE-CDLPEWCNGTSHQCPE---DRYVQD 312
>AC105914-1|AAY41055.1| 820|Homo sapiens unknown protein.
Length = 820
Score = 78.2 bits (184), Expect = 8e-14
Identities = 68/225 (30%), Positives = 94/225 (41%), Gaps = 36/225 (16%)
Query: 334 AHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGLSSSRNHYGQRVI 393
+HLFT L G+ GL+ +G+ R G+CTP + ++N L +
Sbjct: 286 SHLFTTL----GLRGLSGIGAFR-----GMCTP-HRSCAIVTFMNKTLGTF--------- 326
Query: 394 TREADLVTAHEFGHNWGSEHDPDVAECSP--AASQGGSYLMYTYSVSGYDVNNKRFSPCS 451
+ AH GHN G HD D CS G+ + +S Y F +
Sbjct: 327 ----SIAVAHHLGHNLGMNHDEDTCRCSQPRCIMHEGNPPITKFSNCSYG----DFWEYT 378
Query: 452 LRSIRKVLQAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQG 511
+ + +L+ + + CGN VE GEECD G L D CC NC L G
Sbjct: 379 VERTKCLLETVHTKDIFNVKR--CGNGVVEEGEECDCGPLKHCAKDPCCLSNCTL--TDG 434
Query: 512 AVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCP 556
+ C+ CC C F P G VCR+ + C+ CNG S CP
Sbjct: 435 STCA--FGLCCKDCKFLPSGKVCRKEVNE-CDLPEWCNGTSHKCP 476
>D26579-1|BAA05626.1| 824|Homo sapiens transmembrane protein
protein.
Length = 824
Score = 77.8 bits (183), Expect = 1e-13
Identities = 53/164 (32%), Positives = 73/164 (44%), Gaps = 16/164 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GHN G +HD +V C + G +M S + + FS CS + L+
Sbjct: 333 AHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFP---RMFSDCSQAYLESFLE 389
Query: 461 AKSGRCFSE-PEESF------CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAV 513
C + P+ S CGNL VE GE+CD G N C C+L +GA
Sbjct: 390 RPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLA--EGAQ 447
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPK 557
C+ + CC C P G +CR C+ E C+G +CP+
Sbjct: 448 CA--HGTCCQECKVKPAGELCR-PKKDMCDLEEFCDGRHPECPE 488
>BC115404-1|AAI15405.1| 824|Homo sapiens ADAM8 protein protein.
Length = 824
Score = 77.8 bits (183), Expect = 1e-13
Identities = 53/164 (32%), Positives = 73/164 (44%), Gaps = 16/164 (9%)
Query: 402 AHEFGHNWGSEHDPDVAECS-PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
AHE GHN G +HD +V C + G +M S + + FS CS + L+
Sbjct: 333 AHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFP---RMFSDCSQAYLESFLE 389
Query: 461 AKSGRCFSE-PEESF------CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAV 513
C + P+ S CGNL VE GE+CD G N C C+L +GA
Sbjct: 390 RPQSVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLA--EGAQ 447
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPK 557
C+ + CC C P G +CR C+ E C+G +CP+
Sbjct: 448 CA--HGTCCQECKVKPAGELCR-PKKDMCDLEEFCDGRHPECPE 488
>AF171932-1|AAF03780.1| 790|Homo sapiens
metallaproteinase-disintegrin protein.
Length = 790
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 21/163 (12%)
Query: 401 TAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
+AHE GH G HD +C +G + +G FS CS S K +
Sbjct: 336 SAHELGHAVGMSHDEQYCQC-----RGRPNCIMGSGRTG-------FSNCSYISFFKHIS 383
Query: 461 AKSGRCFSEPEESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSD 516
+ + + P + CGN VE EECD G D CC NCKL+ GA CS
Sbjct: 384 SGATCLNNIPGLGYVLKRCGNKIVEDNEECDCGSTEECQKDRCCQSNCKLQ--PGANCS- 440
Query: 517 KNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
CC C F P G VCR+ + C+ C+G S+ CP V
Sbjct: 441 -IGLCCHDCRFRPSGYVCRQEGNE-CDLAEYCDGNSSSCPNDV 481
>BC028372-1|AAH28372.1| 790|Homo sapiens ADAM metallopeptidase
domain 30 protein.
Length = 790
Score = 76.6 bits (180), Expect = 3e-13
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 21/163 (12%)
Query: 401 TAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
+AHE GH G HD +C +G + +G FS CS S K +
Sbjct: 336 SAHELGHAVGMSHDEQYCQC-----RGRLNCIMGSGRTG-------FSNCSYISFFKHIS 383
Query: 461 AKSGRCFSEPEESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSD 516
+ + + P + CGN VE EECD G D CC NCKL+ GA CS
Sbjct: 384 SGATCLNNIPGLGYVLKRCGNKIVEDNEECDCGSTEECQKDRCCQSNCKLQ--PGANCS- 440
Query: 517 KNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
CC C F P G VCR+ + C+ C+G S+ CP V
Sbjct: 441 -IGLCCHDCRFRPSGYVCRQEGNE-CDLAEYCDGNSSSCPNDV 481
>AY358734-1|AAQ89096.1| 790|Homo sapiens ADAM30 protein.
Length = 790
Score = 76.6 bits (180), Expect = 3e-13
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 21/163 (12%)
Query: 401 TAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
+AHE GH G HD +C +G + +G FS CS S K +
Sbjct: 336 SAHELGHAVGMSHDEQYCQC-----RGRLNCIMGSGRTG-------FSNCSYISFFKHIS 383
Query: 461 AKSGRCFSEPEESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSD 516
+ + + P + CGN VE EECD G D CC NCKL+ GA CS
Sbjct: 384 SGATCLNNIPGLGYVLKRCGNKIVEDNEECDCGSTEECQKDRCCQSNCKLQ--PGANCS- 440
Query: 517 KNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
CC C F P G VCR+ + C+ C+G S+ CP V
Sbjct: 441 -IGLCCHDCRFRPSGYVCRQEGNE-CDLAEYCDGNSSSCPNDV 481
>AL359752-8|CAI18978.1| 790|Homo sapiens ADAM metallopeptidase
domain 30 protein.
Length = 790
Score = 76.6 bits (180), Expect = 3e-13
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 21/163 (12%)
Query: 401 TAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQ 460
+AHE GH G HD +C +G + +G FS CS S K +
Sbjct: 336 SAHELGHAVGMSHDEQYCQC-----RGRLNCIMGSGRTG-------FSNCSYISFFKHIS 383
Query: 461 AKSGRCFSEPEESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSD 516
+ + + P + CGN VE EECD G D CC NCKL+ GA CS
Sbjct: 384 SGATCLNNIPGLGYVLKRCGNKIVEDNEECDCGSTEECQKDRCCQSNCKLQ--PGANCS- 440
Query: 517 KNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
CC C F P G VCR+ + C+ C+G S+ CP V
Sbjct: 441 -IGLCCHDCRFRPSGYVCRQEGNE-CDLAEYCDGNSSSCPNDV 481
>AF171933-1|AAF03781.1| 781|Homo sapiens
metallaproteinase-disintegrin beta protein.
Length = 781
Score = 76.2 bits (179), Expect = 3e-13
Identities = 55/162 (33%), Positives = 70/162 (43%), Gaps = 21/162 (12%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH G HD +C +G + +G FS CS S K + +
Sbjct: 337 AHELGHAVGMSHDEQYCQC-----RGRLNCIMGSGRTG-------FSNCSYISFFKHISS 384
Query: 462 KSGRCFSEPEESF----CGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDK 517
+ + P + CGN VE EECD G D CC NCKL+ GA CS
Sbjct: 385 GATCLNNIPGLGYVLKRCGNKIVEDNEECDCGSTEECQKDRCCQSNCKLQ--PGANCS-- 440
Query: 518 NSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
CC C F P G VCR+ + C+ C+G S+ CP V
Sbjct: 441 IGLCCHDCRFRPSGYVCRQEGNE-CDLAEYCDGNSSSCPNDV 481
>D31872-2|BAA06671.1| 518|Homo sapiens
metalloprotease/disintegrin-like protein protein.
Length = 518
Score = 73.3 bits (172), Expect = 2e-12
Identities = 74/245 (30%), Positives = 102/245 (41%), Gaps = 39/245 (15%)
Query: 319 LEVFSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLN 378
L V+ RE + HLF+ F+ G AYVG GIC+ +
Sbjct: 207 LMVYRREGLPEPSDATHLFSGRTFQSTSSGAAYVG--------GICSLSH---------G 249
Query: 379 SGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVS 438
G++ N G +T L G W ++H +C G + T
Sbjct: 250 GGVNEYGN-MGAMAVTLAQTL--GQNLGMMW-NKHRSSAGDCKCPDIWLGCIMEDT---- 301
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEP----EESFCGNLRVEGGEECDAGLLG- 492
G+ + K FS CS+ + LQ G C F++P + CGN VE GEECD G +
Sbjct: 302 GFYLPRK-FSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQE 360
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L A+CSD CC C + P G+ CREA + C+ C G
Sbjct: 361 CSRAGGNCC-KKCTL--THDAMCSD--GLCCRRCKYEPRGVSCREAVNE-CDIAETCTGD 414
Query: 552 SADCP 556
S+ CP
Sbjct: 415 SSQCP 419
>D31872-1|BAA06670.1| 664|Homo sapiens
metalloprotease/disintegrin-like protein protein.
Length = 664
Score = 73.3 bits (172), Expect = 2e-12
Identities = 74/245 (30%), Positives = 102/245 (41%), Gaps = 39/245 (15%)
Query: 319 LEVFSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLN 378
L V+ RE + HLF+ F+ G AYVG GIC+ +
Sbjct: 207 LMVYRREGLPEPSDATHLFSGRTFQSTSSGAAYVG--------GICSLSH---------G 249
Query: 379 SGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVS 438
G++ N G +T L G W ++H +C G + T
Sbjct: 250 GGVNEYGN-MGAMAVTLAQTL--GQNLGMMW-NKHRSSAGDCKCPDIWLGCIMEDT---- 301
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEP----EESFCGNLRVEGGEECDAGLLG- 492
G+ + K FS CS+ + LQ G C F++P + CGN VE GEECD G +
Sbjct: 302 GFYLPRK-FSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQE 360
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L A+CSD CC C + P G+ CREA + C+ C G
Sbjct: 361 CSRAGGNCC-KKCTL--THDAMCSD--GLCCRRCKYEPRGVSCREAVNE-CDIAETCTGD 414
Query: 552 SADCP 556
S+ CP
Sbjct: 415 SSQCP 419
>D17390-1|BAA04213.1| 524|Homo sapiens MDC protein protein.
Length = 524
Score = 73.3 bits (172), Expect = 2e-12
Identities = 74/245 (30%), Positives = 102/245 (41%), Gaps = 39/245 (15%)
Query: 319 LEVFSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLN 378
L V+ RE + HLF+ F+ G AYVG GIC+ +
Sbjct: 213 LMVYRREGLPEPSNATHLFSGRTFQSTSSGAAYVG--------GICSLSH---------G 255
Query: 379 SGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVS 438
G++ N G +T L G W ++H +C G + T
Sbjct: 256 GGVNEYGN-MGAMAVTLAQTL--GQNLGMMW-NKHRSSAGDCKCPDIWLGCIMEDT---- 307
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEP----EESFCGNLRVEGGEECDAGLLG- 492
G+ + K FS CS+ + LQ G C F++P + CGN VE GEECD G +
Sbjct: 308 GFYLPRK-FSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQE 366
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L A+CSD CC C + P G+ CREA + C+ C G
Sbjct: 367 CSRAGGNCC-KKCTL--THDAMCSD--GLCCRRCKYEPRGVSCREAVNE-CDIAETCTGD 420
Query: 552 SADCP 556
S+ CP
Sbjct: 421 SSQCP 425
>AB009675-1|BAA32352.1| 769|Homo sapiens MDC/ADAM11 protein.
Length = 769
Score = 73.3 bits (172), Expect = 2e-12
Identities = 74/245 (30%), Positives = 102/245 (41%), Gaps = 39/245 (15%)
Query: 319 LEVFSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLN 378
L V+ RE + HLF+ F+ G AYVG GIC+ +
Sbjct: 312 LMVYRREGLPEPSDATHLFSGRTFQSTSSGAAYVG--------GICSLSH---------G 354
Query: 379 SGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVS 438
G++ N G +T L G W ++H +C G + T
Sbjct: 355 GGVNEYGN-MGAMAVTLAQTL--GQNLGMMW-NKHRSSAGDCKCPDIWLGCIMEDT---- 406
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEP----EESFCGNLRVEGGEECDAGLLG- 492
G+ + K FS CS+ + LQ G C F++P + CGN VE GEECD G +
Sbjct: 407 GFYLPRK-FSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQE 465
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L A+CSD CC C + P G+ CREA + C+ C G
Sbjct: 466 CSRAGGNCC-KKCTL--THDAMCSD--GLCCRRCKYEPRGVSCREAVNE-CDIAETCTGD 519
Query: 552 SADCP 556
S+ CP
Sbjct: 520 SSQCP 524
>BC125113-1|AAI25114.1| 692|Homo sapiens ADAM33 protein protein.
Length = 692
Score = 72.9 bits (171), Expect = 3e-12
Identities = 44/117 (37%), Positives = 56/117 (47%), Gaps = 14/117 (11%)
Query: 451 SLRSIRKVLQAKSGRCFSEPEE-------SFCGNLRVEGGEECDAGLLGTEDNDMCC-DK 502
S R +R + G C S + + CGN VE GEECD G G E D+CC
Sbjct: 269 SRRQLRAFFRKGGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCG-PGQECRDLCCFAH 327
Query: 503 NCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGV 559
NC LR GA C+ + CC C+ P G +CR+A C+ C G S+ CP V
Sbjct: 328 NCSLR--PGAQCA--HGDCCVRCLLKPAGALCRQAM-GDCDLPEFCTGTSSHCPPDV 379
>BC125118-1|AAI25119.1| 870|Homo sapiens ADAM metallopeptidase
domain 22 protein.
Length = 870
Score = 71.3 bits (167), Expect = 1e-11
Identities = 72/248 (29%), Positives = 103/248 (41%), Gaps = 45/248 (18%)
Query: 322 FSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGL 381
+ R++ + HLF+ +FE G AY+G GIC+ L G+
Sbjct: 315 YRRDFIKEKSDAVHLFSGSQFESSRSGAAYIG--------GICS---------LLKGGGV 357
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDV---AECSPAASQGGSYLMYTYSVS 438
N +G+ T + A HN G D EC + G + T
Sbjct: 358 ----NEFGK---TDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDT---- 406
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLG- 492
GY + K+F+ C++ L + G C F++P + CGN +E GEECD G
Sbjct: 407 GYYLP-KKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAE 465
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L Q + CSD CC C F P G VCREA + C+ C+G
Sbjct: 466 CVLEGAECC-KKCTL--TQDSQCSD--GLCCKKCKFQPMGTVCREAVND-CDIRETCSGN 519
Query: 552 SADCPKGV 559
S+ C +
Sbjct: 520 SSQCAPNI 527
>AF158637-1|AAD55251.1| 867|Homo sapiens
metalloproteinase-disintegrin ADAM22-3 protein.
Length = 867
Score = 71.3 bits (167), Expect = 1e-11
Identities = 72/248 (29%), Positives = 103/248 (41%), Gaps = 45/248 (18%)
Query: 322 FSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGL 381
+ R++ + HLF+ +FE G AY+G GIC+ L G+
Sbjct: 276 YRRDFIKEKSDAVHLFSGSQFESSRSGAAYIG--------GICS---------LLKGGGV 318
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDV---AECSPAASQGGSYLMYTYSVS 438
N +G+ T + A HN G D EC + G + T
Sbjct: 319 ----NEFGK---TDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDT---- 367
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLG- 492
GY + K+F+ C++ L + G C F++P + CGN +E GEECD G
Sbjct: 368 GYYLP-KKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAE 426
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L Q + CSD CC C F P G VCREA + C+ C+G
Sbjct: 427 CVLEGAECC-KKCTL--TQDSQCSD--GLCCKKCKFQPMGTVCREAVND-CDIRETCSGN 480
Query: 552 SADCPKGV 559
S+ C +
Sbjct: 481 SSQCAPNI 488
>AF155382-1|AAF73289.1| 906|Homo sapiens metalloprotease-like,
disintegrin-like, cysteine-rich protein 2 epsilon
protein.
Length = 906
Score = 71.3 bits (167), Expect = 1e-11
Identities = 72/248 (29%), Positives = 103/248 (41%), Gaps = 45/248 (18%)
Query: 322 FSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGL 381
+ R++ + HLF+ +FE G AY+G GIC+ L G+
Sbjct: 315 YRRDFIKEKSDAVHLFSGSQFESSRSGAAYIG--------GICS---------LLKGGGV 357
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDV---AECSPAASQGGSYLMYTYSVS 438
N +G+ T + A HN G D EC + G + T
Sbjct: 358 ----NEFGK---TDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDT---- 406
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLG- 492
GY + K+F+ C++ L + G C F++P + CGN +E GEECD G
Sbjct: 407 GYYLP-KKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAE 465
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L Q + CSD CC C F P G VCREA + C+ C+G
Sbjct: 466 CVLEGAECC-KKCTL--TQDSQCSD--GLCCKKCKFQPMGTVCREAVND-CDIRETCSGN 519
Query: 552 SADCPKGV 559
S+ C +
Sbjct: 520 SSQCAPNI 527
>AF155381-1|AAF73288.1| 899|Homo sapiens metalloprotease-like,
disintegrin-like, cysteine-rich protein 2 delta protein.
Length = 899
Score = 71.3 bits (167), Expect = 1e-11
Identities = 72/248 (29%), Positives = 103/248 (41%), Gaps = 45/248 (18%)
Query: 322 FSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGL 381
+ R++ + HLF+ +FE G AY+G GIC+ L G+
Sbjct: 315 YRRDFIKEKSDAVHLFSGSQFESSRSGAAYIG--------GICS---------LLKGGGV 357
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDV---AECSPAASQGGSYLMYTYSVS 438
N +G+ T + A HN G D EC + G + T
Sbjct: 358 ----NEFGK---TDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDT---- 406
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLG- 492
GY + K+F+ C++ L + G C F++P + CGN +E GEECD G
Sbjct: 407 GYYLP-KKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAE 465
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L Q + CSD CC C F P G VCREA + C+ C+G
Sbjct: 466 CVLEGAECC-KKCTL--TQDSQCSD--GLCCKKCKFQPMGTVCREAVND-CDIRETCSGN 519
Query: 552 SADCPKGV 559
S+ C +
Sbjct: 520 SSQCAPNI 527
>AF073291-1|AAF22476.2| 870|Homo sapiens MDC2 protein.
Length = 870
Score = 71.3 bits (167), Expect = 1e-11
Identities = 72/248 (29%), Positives = 103/248 (41%), Gaps = 45/248 (18%)
Query: 322 FSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGL 381
+ R++ + HLF+ +FE G AY+G GIC+ L G+
Sbjct: 315 YRRDFIKEKSDAVHLFSGSQFESSRSGAAYIG--------GICS---------LLKGGGV 357
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDV---AECSPAASQGGSYLMYTYSVS 438
N +G+ T + A HN G D EC + G + T
Sbjct: 358 ----NEFGK---TDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDT---- 406
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLG- 492
GY + K+F+ C++ L + G C F++P + CGN +E GEECD G
Sbjct: 407 GYYLP-KKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAE 465
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L Q + CSD CC C F P G VCREA + C+ C+G
Sbjct: 466 CVLEGAECC-KKCTL--TQDSQCSD--GLCCKKCKFQPMGTVCREAVND-CDIRETCSGN 519
Query: 552 SADCPKGV 559
S+ C +
Sbjct: 520 SSQCAPNI 527
>AB009671-2|BAA32350.1| 823|Homo sapiens MDC2 beta protein.
Length = 823
Score = 71.3 bits (167), Expect = 1e-11
Identities = 72/248 (29%), Positives = 103/248 (41%), Gaps = 45/248 (18%)
Query: 322 FSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGL 381
+ R++ + HLF+ +FE G AY+G GIC+ L G+
Sbjct: 315 YRRDFIKEKSDAVHLFSGSQFESSRSGAAYIG--------GICS---------LLKGGGV 357
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDV---AECSPAASQGGSYLMYTYSVS 438
N +G+ T + A HN G D EC + G + T
Sbjct: 358 ----NEFGK---TDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDT---- 406
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLG- 492
GY + K+F+ C++ L + G C F++P + CGN +E GEECD G
Sbjct: 407 GYYLP-KKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAE 465
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L Q + CSD CC C F P G VCREA + C+ C+G
Sbjct: 466 CVLEGAECC-KKCTL--TQDSQCSD--GLCCKKCKFQPMGTVCREAVND-CDIRETCSGN 519
Query: 552 SADCPKGV 559
S+ C +
Sbjct: 520 SSQCAPNI 527
>AB009671-1|BAA32349.1| 859|Homo sapiens MDC2 alpha protein.
Length = 859
Score = 71.3 bits (167), Expect = 1e-11
Identities = 72/248 (29%), Positives = 103/248 (41%), Gaps = 45/248 (18%)
Query: 322 FSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGL 381
+ R++ + HLF+ +FE G AY+G GIC+ L G+
Sbjct: 315 YRRDFIKEKSDAVHLFSGSQFESSRSGAAYIG--------GICS---------LLKGGGV 357
Query: 382 SSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDV---AECSPAASQGGSYLMYTYSVS 438
N +G+ T + A HN G D EC + G + T
Sbjct: 358 ----NEFGK---TDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDT---- 406
Query: 439 GYDVNNKRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLG- 492
GY + K+F+ C++ L + G C F++P + CGN +E GEECD G
Sbjct: 407 GYYLP-KKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAE 465
Query: 493 -TEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGA 551
+ CC K C L Q + CSD CC C F P G VCREA + C+ C+G
Sbjct: 466 CVLEGAECC-KKCTL--TQDSQCSD--GLCCKKCKFQPMGTVCREAVND-CDIRETCSGN 519
Query: 552 SADCPKGV 559
S+ C +
Sbjct: 520 SSQCAPNI 527
>BC043207-1|AAH43207.2| 559|Homo sapiens ADAM7 protein protein.
Length = 559
Score = 70.5 bits (165), Expect = 2e-11
Identities = 50/164 (30%), Positives = 71/164 (43%), Gaps = 23/164 (14%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AH+ GHN G +HD P G +M S + +FS CS + L+
Sbjct: 149 AHQLGHNLGMQHDE-----FPCTCPSGKCVMD----SDGSIPALKFSKCSQNQYHQYLKD 199
Query: 462 KSGRC-------FSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKN-CKLRKNQGAV 513
C ++ + FCGN +++ GEECD G E + CCD + C L+ G
Sbjct: 200 YKPTCMLNIPFPYNFHDFQFCGNKKLDEGEECDCG-PAQECTNPCCDAHTCVLK--PGFT 256
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPK 557
C++ CC C G +CR A C+ +C G S CPK
Sbjct: 257 CAE--GECCESCQIKKAGSICR-PAKDECDFPEMCTGHSPACPK 297
>AF215824-1|AAG43987.1| 754|Homo sapiens a disintegrin and
metalloproteinase 7 protein.
Length = 754
Score = 70.5 bits (165), Expect = 2e-11
Identities = 50/164 (30%), Positives = 71/164 (43%), Gaps = 23/164 (14%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AH+ GHN G +HD P G +M S + +FS CS + L+
Sbjct: 334 AHQLGHNLGMQHDE-----FPCTCPSGKCVMD----SDGSIPALKFSKCSQNQYHQYLKD 384
Query: 462 KSGRC-------FSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKN-CKLRKNQGAV 513
C ++ + FCGN +++ GEECD G E + CCD + C L+ G
Sbjct: 385 YKPTCMLNIPFPYNFHDFQFCGNKKLDEGEECDCG-PAQECTNPCCDAHTCVLK--PGFT 441
Query: 514 CSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPK 557
C++ CC C G +CR A C+ +C G S CPK
Sbjct: 442 CAE--GECCESCQIKKAGSICR-PAKDECDFPEMCTGHSPACPK 482
>BC034975-1|AAH34975.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 70.1 bits (164), Expect = 2e-11
Identities = 42/119 (35%), Positives = 56/119 (47%), Gaps = 12/119 (10%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEPE------ESFCGNLRVEGGEECDAGLLGTEDND 497
K FS CSLRS + + +C ++P+ + CGN R+EG E CD G
Sbjct: 357 KTFSSCSLRSFQNFISNVGVKCLQNKPQMQKKSPKPVCGNGRLEGNEICDCGTEAQCGPA 416
Query: 498 MCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADC 555
CCD + C L+ GA C CC C G+ CR AH C+ CNG+S +C
Sbjct: 417 SCCDFRTCVLK--DGAKCY--KGLCCKDCQILQSGVECRPKAHPECDIAENCNGSSPEC 471
>BC030698-1|AAH30698.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 70.1 bits (164), Expect = 2e-11
Identities = 42/119 (35%), Positives = 56/119 (47%), Gaps = 12/119 (10%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEPE------ESFCGNLRVEGGEECDAGLLGTEDND 497
K FS CSLRS + + +C ++P+ + CGN R+EG E CD G
Sbjct: 357 KTFSSCSLRSFQNFISNVGVKCLQNKPQMQKKSPKPVCGNGRLEGNEICDCGTEAQCGPA 416
Query: 498 MCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADC 555
CCD + C L+ GA C CC C G+ CR AH C+ CNG+S +C
Sbjct: 417 SCCDFRTCVLK--DGAKCY--KGLCCKDCQILQSGVECRPKAHPECDIAENCNGSSPEC 471
>BC030014-1|AAH30014.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 70.1 bits (164), Expect = 2e-11
Identities = 42/119 (35%), Positives = 56/119 (47%), Gaps = 12/119 (10%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEPE------ESFCGNLRVEGGEECDAGLLGTEDND 497
K FS CSLRS + + +C ++P+ + CGN R+EG E CD G
Sbjct: 357 KTFSSCSLRSFQNFISNVGVKCLQNKPQMQKKSPKPVCGNGRLEGNEICDCGTEAQCGPA 416
Query: 498 MCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADC 555
CCD + C L+ GA C CC C G+ CR AH C+ CNG+S +C
Sbjct: 417 SCCDFRTCVLK--DGAKCY--KGLCCKDCQILQSGVECRPKAHPECDIAENCNGSSPEC 471
>BC028702-1|AAH28702.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 70.1 bits (164), Expect = 2e-11
Identities = 42/119 (35%), Positives = 56/119 (47%), Gaps = 12/119 (10%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEPE------ESFCGNLRVEGGEECDAGLLGTEDND 497
K FS CSLRS + + +C ++P+ + CGN R+EG E CD G
Sbjct: 357 KTFSSCSLRSFQNFISNVGVKCLQNKPQMQKKSPKPVCGNGRLEGNEICDCGTEAQCGPA 416
Query: 498 MCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADC 555
CCD + C L+ GA C CC C G+ CR AH C+ CNG+S +C
Sbjct: 417 SCCDFRTCVLK--DGAKCY--KGLCCKDCQILQSGVECRPKAHPECDIAENCNGSSPEC 471
>BC026169-1|AAH26169.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 70.1 bits (164), Expect = 2e-11
Identities = 42/119 (35%), Positives = 56/119 (47%), Gaps = 12/119 (10%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEPE------ESFCGNLRVEGGEECDAGLLGTEDND 497
K FS CSLRS + + +C ++P+ + CGN R+EG E CD G
Sbjct: 357 KTFSSCSLRSFQNFISNVGVKCLQNKPQMQKKSPKPVCGNGRLEGNEICDCGTEAQCGPA 416
Query: 498 MCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADC 555
CCD + C L+ GA C CC C G+ CR AH C+ CNG+S +C
Sbjct: 417 SCCDFRTCVLK--DGAKCY--KGLCCKDCQILQSGVECRPKAHPECDIAENCNGSSPEC 471
>BC026085-1|AAH26085.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 70.1 bits (164), Expect = 2e-11
Identities = 42/119 (35%), Positives = 56/119 (47%), Gaps = 12/119 (10%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEPE------ESFCGNLRVEGGEECDAGLLGTEDND 497
K FS CSLRS + + +C ++P+ + CGN R+EG E CD G
Sbjct: 357 KTFSSCSLRSFQNFISNVGVKCLQNKPQMQKKSPKPVCGNGRLEGNEICDCGTEAQCGPA 416
Query: 498 MCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADC 555
CCD + C L+ GA C CC C G+ CR AH C+ CNG+S +C
Sbjct: 417 SCCDFRTCVLK--DGAKCY--KGLCCKDCQILQSGVECRPKAHPECDIAENCNGSSPEC 471
>AY358739-1|AAQ89099.1| 787|Homo sapiens similar to MDC family
protein.
Length = 787
Score = 70.1 bits (164), Expect = 2e-11
Identities = 42/119 (35%), Positives = 56/119 (47%), Gaps = 12/119 (10%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEPE------ESFCGNLRVEGGEECDAGLLGTEDND 497
K FS CSLRS + + +C ++P+ + CGN R+EG E CD G
Sbjct: 357 KTFSSCSLRSFQNFISNVGVKCLQNKPQMQKKSPKPVCGNGRLEGNEICDCGTEAQCGPA 416
Query: 498 MCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADC 555
CCD + C L+ GA C CC C G+ CR AH C+ CNG+S +C
Sbjct: 417 SCCDFRTCVLK--DGAKCY--KGLCCKDCQILQSGVECRPKAHPECDIAENCNGSSPEC 471
>AC092206-1|AAX93091.1| 131|Homo sapiens unknown protein.
Length = 131
Score = 69.7 bits (163), Expect = 3e-11
Identities = 37/77 (48%), Positives = 48/77 (62%), Gaps = 6/77 (7%)
Query: 213 RTKRQSDYEYTPTKTRCPLLLVADYRFFQEMGASNTKTTISYLISLIDRVHKIYNDTLWQ 272
R KR++D + P K C LL+VAD+RF++ MG TT +YLI LIDRV IY +T W
Sbjct: 61 RVKRRADPD--PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSW- 117
Query: 273 DRQDMDGFKGMGFVIKK 289
D GFKG G I++
Sbjct: 118 ---DNAGFKGYGIQIEQ 131
Score = 35.1 bits (77), Expect = 0.78
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
Query: 119 PSWRHLPDLDGKSMITYRSSDIRYSWAGDAIPNKPRVCGYVKEGKELEDDSDDVQEEYDI 178
P WR + D K M+ Y+S DI+ + P+VCGY+K E V E
Sbjct: 1 PLWRFVNDTKDKRMLVYKSEDIK----NVSRLQSPKVCGYLKVDNEELLPKGLVDREPPE 56
Query: 179 ELKH 182
EL H
Sbjct: 57 ELVH 60
>AF090327-1|AAC36742.1| 588|Homo sapiens sperm maturation-related
glycoprotein GP-83 protein.
Length = 588
Score = 68.1 bits (159), Expect = 9e-11
Identities = 46/159 (28%), Positives = 69/159 (43%), Gaps = 13/159 (8%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCS--LRSIRKVL 459
AH+ GHN G +HD C G + S+ D++ R + L+ +
Sbjct: 168 AHQLGHNLGMQHDEFPCTCP----SGKCVMDSDGSIPALDLSKCRQNQYHQYLKDYKPTC 223
Query: 460 QAKSGRCFSEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKN-CKLRKNQGAVCSDKN 518
++ + FCGN +++ GEECD G E + CCD + C L+ G C++
Sbjct: 224 MLNIPFPYNFHDFQFCGNKKLDEGEECDCG-PAQECTNPCCDAHTCVLK--PGFTCAE-- 278
Query: 519 SPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPK 557
CC C G +CR A C+ +C G S CPK
Sbjct: 279 GECCESCQIKKAGSICR-PAKDECDFPEMCTGHSPACPK 316
>U52370-1|AAC51110.1| 735|Homo sapiens fertilin beta protein.
Length = 735
Score = 66.5 bits (155), Expect = 3e-10
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 22/127 (17%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEP-------EESFCGNLRVEGGEECDAGLLGTEDN 496
K FS CS + + +C ++P +++ CGN ++E GEECD GTE +
Sbjct: 349 KIFSNCSFEDFAHFISKQKSQCLHNQPRLDPFFKQQAVCGNAKLEAGEECDC---GTEQD 405
Query: 497 -----DMCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNG 550
+ CCD C+ + G+ C++ PCC C+F +CR + C+ CNG
Sbjct: 406 CALIGETCCDIATCRFK--AGSNCAE--GPCCENCLFMSKERMCR-PSFEECDLPEYCNG 460
Query: 551 ASADCPK 557
+SA CP+
Sbjct: 461 SSASCPE 467
>U38805-1|AAD04206.1| 734|Homo sapiens fertilin beta protein.
Length = 734
Score = 66.5 bits (155), Expect = 3e-10
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 22/127 (17%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEP-------EESFCGNLRVEGGEECDAGLLGTEDN 496
K FS CS + + +C ++P +++ CGN ++E GEECD GTE +
Sbjct: 348 KIFSNCSFEDFAHFISKQKSQCLHNQPRLDPFFKQQAVCGNAKLEAGEECDC---GTEQD 404
Query: 497 -----DMCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNG 550
+ CCD C+ + G+ C++ PCC C+F +CR + C+ CNG
Sbjct: 405 CALIGETCCDIATCRFK--AGSNCAE--GPCCENCLFMSKERMCR-PSFEECDLPEYCNG 459
Query: 551 ASADCPK 557
+SA CP+
Sbjct: 460 SSASCPE 466
>BC064547-1|AAH64547.1| 579|Homo sapiens ADAM2 protein protein.
Length = 579
Score = 66.5 bits (155), Expect = 3e-10
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 22/127 (17%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEP-------EESFCGNLRVEGGEECDAGLLGTEDN 496
K FS CS + + +C ++P +++ CGN ++E GEECD GTE +
Sbjct: 223 KIFSNCSFEDFAHFISKQKSQCLHNQPRLDPFFKQQAVCGNAKLEAGEECDC---GTEQD 279
Query: 497 -----DMCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNG 550
+ CCD C+ + G+ C++ PCC C+F +CR + C+ CNG
Sbjct: 280 CALIGETCCDIATCRFK--AGSNCAE--GPCCENCLFMSKERMCR-PSFEECDLPEYCNG 334
Query: 551 ASADCPK 557
+SA CP+
Sbjct: 335 SSASCPE 341
>BC034957-1|AAH34957.1| 716|Homo sapiens ADAM2 protein protein.
Length = 716
Score = 66.5 bits (155), Expect = 3e-10
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 22/127 (17%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEP-------EESFCGNLRVEGGEECDAGLLGTEDN 496
K FS CS + + +C ++P +++ CGN ++E GEECD GTE +
Sbjct: 330 KIFSNCSFEDFAHFISKQKSQCLHNQPRLDPFFKQQAVCGNAKLEAGEECDC---GTEQD 386
Query: 497 -----DMCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNG 550
+ CCD C+ + G+ C++ PCC C+F +CR + C+ CNG
Sbjct: 387 CALIGETCCDIATCRFK--AGSNCAE--GPCCENCLFMSKERMCR-PSFEECDLPEYCNG 441
Query: 551 ASADCPK 557
+SA CP+
Sbjct: 442 SSASCPE 448
>AJ133005-1|CAB40813.1| 735|Homo sapiens fertilin beta protein
protein.
Length = 735
Score = 66.5 bits (155), Expect = 3e-10
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 22/127 (17%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEP-------EESFCGNLRVEGGEECDAGLLGTEDN 496
K FS CS + + +C ++P +++ CGN ++E GEECD GTE +
Sbjct: 349 KIFSNCSFEDFAHFISKQKSQCLHNQPRLDPFFKQQAVCGNAKLEAGEECDC---GTEQD 405
Query: 497 -----DMCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNG 550
+ CCD C+ + G+ C++ PCC C+F +CR + C+ CNG
Sbjct: 406 CALIGETCCDIATCRFK--AGSNCAE--GPCCENCLFMSKERMCR-PSFEECDLPEYCNG 460
Query: 551 ASADCPK 557
+SA CP+
Sbjct: 461 SSASCPE 467
>BC121045-1|AAI21046.1| 739|Homo sapiens ADAM metallopeptidase
domain 18 protein.
Length = 739
Score = 60.1 bits (139), Expect = 2e-08
Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 22/168 (13%)
Query: 399 LVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKV 458
++ A G N G +D D+ +C + + +M +VS K FS CS+ R
Sbjct: 315 VIIAQLLGLNVGLTYD-DITQCFCLRA---TCIMNHEAVSAS--GRKIFSNCSMHDYRYF 368
Query: 459 LQAKSGRCFSE--------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKN-CKLRKN 509
+ +C + + CGN +E EECD G CCD N CKL+
Sbjct: 369 VSKFETKCLQKLSNLQPLHQNQPVCGNGILESNEECDCGNKNECQFKKCCDYNTCKLK-- 426
Query: 510 QGAV-CSDKNSPCCAG-CVFAPPGLVCREAAHSACEGEAICNGASADC 555
G+V C + PCC C + G CR++ C+ CNG S++C
Sbjct: 427 -GSVKCG--SGPCCTSKCELSIAGTPCRKSIDPECDFTEYCNGTSSNC 471
>AY358321-1|AAQ88687.1| 715|Homo sapiens ADAM18 protein.
Length = 715
Score = 60.1 bits (139), Expect = 2e-08
Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 22/168 (13%)
Query: 399 LVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKV 458
++ A G N G +D D+ +C + + +M +VS K FS CS+ R
Sbjct: 291 VIIAQLLGLNVGLTYD-DITQCFCLRA---TCIMNHEAVSAS--GRKIFSNCSMHDYRYF 344
Query: 459 LQAKSGRCFSE--------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKN-CKLRKN 509
+ +C + + CGN +E EECD G CCD N CKL+
Sbjct: 345 VSKFETKCLQKLSNLQPLHQNQPVCGNGILESNEECDCGNKNECQFKKCCDYNTCKLK-- 402
Query: 510 QGAV-CSDKNSPCCAG-CVFAPPGLVCREAAHSACEGEAICNGASADC 555
G+V C + PCC C + G CR++ C+ CNG S++C
Sbjct: 403 -GSVKCG--SGPCCTSKCELSIAGTPCRKSIDPECDFTEYCNGTSSNC 447
>AJ133004-1|CAB40812.1| 739|Homo sapiens tMDC III protein protein.
Length = 739
Score = 60.1 bits (139), Expect = 2e-08
Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 22/168 (13%)
Query: 399 LVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKV 458
++ A G N G +D D+ +C + + +M +VS K FS CS+ R
Sbjct: 315 VIIAQLLGLNVGLTYD-DITQCFCLRA---TCIMNHEAVSAS--GRKIFSNCSMHDYRYF 368
Query: 459 LQAKSGRCFSE--------PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKN-CKLRKN 509
+ +C + + CGN +E EECD G CCD N CKL+
Sbjct: 369 VSKFETKCLQKLSNLQPLHQNQPVCGNGILESNEECDCGNKNECQFKKCCDYNTCKLK-- 426
Query: 510 QGAV-CSDKNSPCCAG-CVFAPPGLVCREAAHSACEGEAICNGASADC 555
G+V C + PCC C + G CR++ C+ CNG S++C
Sbjct: 427 -GSVKCG--SGPCCTSKCELSIAGTPCRKSIDPECDFTEYCNGTSSNC 471
>X99374-1|CAA67753.1| 735|Homo sapiens fertilin beta protein.
Length = 735
Score = 58.4 bits (135), Expect = 7e-08
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 22/127 (17%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRCF-SEP-------EESFCGNLRVEGGEECDAGLLGTEDN 496
K FS CS + + +C ++P +++ C N ++E G+E D G TE +
Sbjct: 349 KIFSNCSFEDFAHFISKQKSQCLHNQPRLDPFFKQQAVCSNAKLEAGDEFDCG---TEQD 405
Query: 497 -----DMCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNG 550
+ CCD C+ + G+ C++ PCC C+F +CR + C+ CNG
Sbjct: 406 CALIGETCCDIATCRFKA--GSNCAE--GPCCENCLFMSKERMCRPSFEE-CDLPEYCNG 460
Query: 551 ASADCPK 557
+SA CP+
Sbjct: 461 SSASCPE 467
>AC073195-1|AAX93142.1| 150|Homo sapiens unknown protein.
Length = 150
Score = 48.4 bits (110), Expect = 8e-05
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 4/107 (3%)
Query: 12 ASIQSTGIVKRGAKLSNHPYNTIKEVRFKTLGKDFRLILHPQSSVLHSNFKAYSVDADGK 71
++IQ + KR + S H T+ + F L + F+L L + NFK VD
Sbjct: 48 SNIQQHSVRKRDLQTSTH-VETL--LTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKN- 103
Query: 72 ETTVHVDRENFFTGRVFGETKSDVKLHMEDGVMTGIIHTPDETYHVE 118
E+ V ++FFTG V GE S V H+ D + I+T Y++E
Sbjct: 104 ESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIE 150
>BC033132-1|AAH33132.1| 488|Homo sapiens ADAM19 protein protein.
Length = 488
Score = 48.0 bits (109), Expect = 1e-04
Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 6/64 (9%)
Query: 494 EDNDMCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGAS 552
E N+ CC+ NC LR GA C+ + CC C PG +CRE A C+ C G S
Sbjct: 7 ECNNPCCNASNCTLRP--GAECA--HGSCCHQCKLLAPGTLCREQARQ-CDLPEFCTGKS 61
Query: 553 ADCP 556
CP
Sbjct: 62 PHCP 65
>BC024214-1|AAH24214.2| 488|Homo sapiens ADAM19 protein protein.
Length = 488
Score = 48.0 bits (109), Expect = 1e-04
Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 6/64 (9%)
Query: 494 EDNDMCCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGAS 552
E N+ CC+ NC LR GA C+ + CC C PG +CRE A C+ C G S
Sbjct: 7 ECNNPCCNASNCTLRP--GAECA--HGSCCHQCKLLAPGTLCREQARQ-CDLPEFCTGKS 61
Query: 553 ADCP 556
CP
Sbjct: 62 PHCP 65
>AF158642-1|AAD55253.1| 88|Homo sapiens
metalloproteinase-disintegrin protein.
Length = 88
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 12/88 (13%)
Query: 445 KRFSPCSLRSIRKVLQAKSGRC-FSEPEESF----CGNLRVEGGEECDAGLLG--TEDND 497
K+F+ C++ L + G C F++P + CGN +E GEECD G +
Sbjct: 5 KKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAECVLEGA 64
Query: 498 MCCDKNCKLRKNQGAVCSDKNSPCCAGC 525
CC K C L Q + CSD CC C
Sbjct: 65 ECC-KKCTL--TQDSQCSD--GLCCKKC 87
>AY172952-1|AAO45696.1| 629|Homo sapiens metalloproteinase 12-like
protein protein.
Length = 629
Score = 44.0 bits (99), Expect = 0.002
Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 499 CCD-KNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADC 555
CCD + C L+ GA C CC C G+ CR AH C+ CNG+S +C
Sbjct: 312 CCDFRTCVLK--DGAKCY--KGLCCKDCQILQSGVECRPKAHPECDIAENCNGSSPEC 365
>AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.
Length = 1207
Score = 41.9 bits (94), Expect = 0.007
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN G HD D C+ G ++M + G ++ + +S CS + + L++
Sbjct: 481 AHEMGHNMGINHDNDHPSCA-----DGLHIMSGEWIKGQNLGDVSWSRCSKEDLERFLRS 535
Query: 462 KSGRC 466
K+ C
Sbjct: 536 KASNC 540
>DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif 17 protein.
Length = 1095
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN G HD D + C+ G S++M V G + ++ +S CS + L++
Sbjct: 388 AHELGHNLGMNHDDDHSSCA-----GRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKS 442
Query: 462 KSGRC 466
K C
Sbjct: 443 KVSTC 447
>AK131344-1|BAD18500.1| 502|Homo sapiens protein ( Homo sapiens
cDNA FLJ16363 fis, clone THYMU2031139, weakly similar
to Homo sapiens zinc metalloprotease ADAMTS7 (ADAMTS7)
mRNA. ).
Length = 502
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN G HD D + C+ G S++M V G + ++ +S CS + L++
Sbjct: 145 AHELGHNLGMNHDDDHSSCA-----GRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKS 199
Query: 462 KSGRC 466
K C
Sbjct: 200 KVSTC 204
>AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease
disintegrin 17, with thrombospondin domains protein.
Length = 1095
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN G HD D + C+ G S++M V G + ++ +S CS + L++
Sbjct: 388 AHELGHNLGMNHDDDHSSCA-----GRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKS 442
Query: 462 KSGRC 466
K C
Sbjct: 443 KVSTC 447
>BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 7 protein.
Length = 1686
Score = 38.7 bits (86), Expect = 0.063
Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G +HD +C P + ++M + YD +S CS + I + L
Sbjct: 387 AHELGHSFGIQHDGSGNDCEPVGKR--PFIMSPQLL--YDAAPLTWSRCSRQYITRFLDR 442
Query: 462 KSGRCFSEP 470
G C +P
Sbjct: 443 GWGLCLDDP 451
>AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein.
Length = 1686
Score = 38.7 bits (86), Expect = 0.063
Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G +HD +C P + ++M + YD +S CS + I + L
Sbjct: 387 AHELGHSFGIQHDGSGNDCEPVGKR--PFIMSPQLL--YDAAPLTWSRCSRQYITRFLDR 442
Query: 462 KSGRCFSEP 470
G C +P
Sbjct: 443 GWGLCLDDP 451
>AF140675-1|AAD56358.1| 997|Homo sapiens zinc metalloprotease
ADAMTS7 protein.
Length = 997
Score = 38.7 bits (86), Expect = 0.063
Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G +HD +C P + ++M + YD +S CS + I + L
Sbjct: 387 AHELGHSFGIQHDGSGNDCEPVGKR--PFIMSPQLL--YDAAPLTWSRCSRQYITRFLDR 442
Query: 462 KSGRCFSEP 470
G C +P
Sbjct: 443 GWGLCLDDP 451
>AB209497-1|BAD92734.1| 527|Homo sapiens a disintegrin and
metalloprotease with thrombospondin motifs-7
preproprotein va protein.
Length = 527
Score = 38.7 bits (86), Expect = 0.063
Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G +HD +C P + ++M + YD +S CS + I + L
Sbjct: 352 AHELGHSFGIQHDGSGNDCEPVGKR--PFIMSPQLL--YDAAPLTWSRCSRQYITRFLDR 407
Query: 462 KSGRCFSEP 470
G C +P
Sbjct: 408 GWGLCLDDP 416
>BC036515-1|AAH36515.1| 967|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 1 protein.
Length = 967
Score = 37.5 bits (83), Expect = 0.15
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 396 EADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSI 455
+A TAHE GH + HD D +C+ M +S D +++ +SPCS I
Sbjct: 394 QAAFTTAHELGHVFNMPHD-DAKQCASLNGVNQDSHMMASMLSNLD-HSQPWSPCSAYMI 451
Query: 456 RKVLQAKSGRCFSEPEES 473
L G C + ++
Sbjct: 452 TSFLDNGHGECLMDKPQN 469
>AP001697-1|BAA95502.1| 967|Homo sapiens metalloprotease with
thrombospondin type 1 motifs protein.
Length = 967
Score = 37.5 bits (83), Expect = 0.15
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 396 EADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSI 455
+A TAHE GH + HD D +C+ M +S D +++ +SPCS I
Sbjct: 394 QAAFTTAHELGHVFNMPHD-DAKQCASLNGVNQDSHMMASMLSNLD-HSQPWSPCSAYMI 451
Query: 456 RKVLQAKSGRCFSEPEES 473
L G C + ++
Sbjct: 452 TSFLDNGHGECLMDKPQN 469
>AF207664-1|AAF23772.1| 967|Homo sapiens matrix metalloprotease
protein.
Length = 967
Score = 37.5 bits (83), Expect = 0.15
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 396 EADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSI 455
+A TAHE GH + HD D +C+ M +S D +++ +SPCS I
Sbjct: 394 QAAFTTAHELGHVFNMPHD-DAKQCASLNGVNQDSHMMASMLSNLD-HSQPWSPCSAYMI 451
Query: 456 RKVLQAKSGRCFSEPEES 473
L G C + ++
Sbjct: 452 TSFLDNGHGECLMDKPQN 469
>AF060152-1|AAD48080.1| 950|Homo sapiens METH1 protein protein.
Length = 950
Score = 37.5 bits (83), Expect = 0.15
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 396 EADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSI 455
+A TAHE GH + HD D +C+ M +S D +++ +SPCS I
Sbjct: 377 QAAFTTAHELGHVFNMPHD-DAKQCASLNGVNQDSHMMASMLSNLD-HSQPWSPCSAYMI 434
Query: 456 RKVLQAKSGRCFSEPEES 473
L G C + ++
Sbjct: 435 TSFLDNGHGECLMDKPQN 452
>AB037767-1|BAA92584.1| 999|Homo sapiens KIAA1346 protein protein.
Length = 999
Score = 37.5 bits (83), Expect = 0.15
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 396 EADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSI 455
+A TAHE GH + HD D +C+ M +S D +++ +SPCS I
Sbjct: 426 QAAFTTAHELGHVFNMPHD-DAKQCASLNGVNQDSHMMASMLSNLD-HSQPWSPCSAYMI 483
Query: 456 RKVLQAKSGRCFSEPEES 473
L G C + ++
Sbjct: 484 TSFLDNGHGECLMDKPQN 501
>Y13323-1|CAA73764.2| 470|Homo sapiens disintegrin-protease
protein.
Length = 470
Score = 37.1 bits (82), Expect = 0.19
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 17/116 (14%)
Query: 400 VTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVL 459
V +HE GH G P +C GS +M Y S + K FS + L
Sbjct: 349 VMSHELGHVLGMPDVPFNTKCP-----SGSCVMNQYLSSKFP---KDFSTSCRAHFERYL 400
Query: 460 QAKSGRCFSEPE-------ESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLR 507
++ +C + CGN +E GE+CD G E ++CC+ CKL+
Sbjct: 401 LSQKPKCLLQAPIPTNIMTTPVCGNHLLEVGEDCDCG-SPKECTNLCCEALTCKLK 455
>BC074878-1|AAH74878.1| 470|Homo sapiens ADAM-like, decysin 1
protein.
Length = 470
Score = 37.1 bits (82), Expect = 0.19
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 17/116 (14%)
Query: 400 VTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVL 459
V +HE GH G P +C GS +M Y S + K FS + L
Sbjct: 349 VMSHELGHVLGMPDVPFNTKCP-----SGSCVMNQYLSSKFP---KDFSTSCRAHFERYL 400
Query: 460 QAKSGRCFSEPE-------ESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLR 507
++ +C + CGN +E GE+CD G E ++CC+ CKL+
Sbjct: 401 LSQKPKCLLQAPIPTNIMTTPVCGNHLLEVGEDCDCG-SPKECTNLCCEALTCKLK 455
>BC074877-1|AAH74877.1| 470|Homo sapiens ADAM-like, decysin 1
protein.
Length = 470
Score = 37.1 bits (82), Expect = 0.19
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 17/116 (14%)
Query: 400 VTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVL 459
V +HE GH G P +C GS +M Y S + K FS + L
Sbjct: 349 VMSHELGHVLGMPDVPFNTKCP-----SGSCVMNQYLSSKFP---KDFSTSCRAHFERYL 400
Query: 460 QAKSGRCFSEPE-------ESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLR 507
++ +C + CGN +E GE+CD G E ++CC+ CKL+
Sbjct: 401 LSQKPKCLLQAPIPTNIMTTPVCGNHLLEVGEDCDCG-SPKECTNLCCEALTCKLK 455
>BC069582-1|AAH69582.1| 470|Homo sapiens ADAM-like, decysin 1
protein.
Length = 470
Score = 37.1 bits (82), Expect = 0.19
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 17/116 (14%)
Query: 400 VTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVL 459
V +HE GH G P +C GS +M Y S + K FS + L
Sbjct: 349 VMSHELGHVLGMPDVPFNTKCP-----SGSCVMNQYLSSKFP---KDFSTSCRAHFERYL 400
Query: 460 QAKSGRCFSEPE-------ESFCGNLRVEGGEECDAGLLGTEDNDMCCDK-NCKLR 507
++ +C + CGN +E GE+CD G E ++CC+ CKL+
Sbjct: 401 LSQKPKCLLQAPIPTNIMTTPVCGNHLLEVGEDCDCG-SPKECTNLCCEALTCKLK 455
>AF170084-1|AAF15317.1| 967|Homo sapiens metalloproteinase with
thrombospondin type 1 motifs ADAMTS1 protein.
Length = 967
Score = 37.1 bits (82), Expect = 0.19
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 2/74 (2%)
Query: 396 EADLVTAHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSI 455
+A TAHE GH + HD D +C+ M +S D +++ +SPCS I
Sbjct: 394 QAAFTTAHELGHVFNMPHD-DAKQCASLNGVNQDSHMMASMLSNLD-HSQPWSPCSAYMI 451
Query: 456 RKVLQAKSGRCFSE 469
L G C +
Sbjct: 452 TSFLDNGHGECLMD 465
>AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar to
mouse Jedi soluble isoform 736 protein protein.
Length = 1037
Score = 36.3 bits (80), Expect = 0.34
Identities = 29/102 (28%), Positives = 39/102 (38%), Gaps = 13/102 (12%)
Query: 464 GRCFSEPEESFC--GNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPC 521
GRC + P + C G + EC G+ G + CDK C N C K+ C
Sbjct: 112 GRCVA-PNQCQCVPGWRGDDCSSECAPGMWGPQ-----CDKPCSCGNNSS--CDPKSGVC 163
Query: 522 CAGCVFAPPGLV--CREAAHS-ACEGEAICNGASADCPKGVC 560
PP + C + AC+ C+GA D G C
Sbjct: 164 SCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGAC 205
>AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar to
mouse Jedi soluble isoform 736 protein protein.
Length = 1037
Score = 36.3 bits (80), Expect = 0.34
Identities = 29/102 (28%), Positives = 39/102 (38%), Gaps = 13/102 (12%)
Query: 464 GRCFSEPEESFC--GNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPC 521
GRC + P + C G + EC G+ G + CDK C N C K+ C
Sbjct: 112 GRCVA-PNQCQCVPGWRGDDCSSECAPGMWGPQ-----CDKPCSCGNNSS--CDPKSGVC 163
Query: 522 CAGCVFAPPGLV--CREAAHS-ACEGEAICNGASADCPKGVC 560
PP + C + AC+ C+GA D G C
Sbjct: 164 SCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGAC 205
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 35.5 bits (78), Expect = 0.59
Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 8/84 (9%)
Query: 483 GEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSAC 542
GE C+A L + CDK C C + C C GL C E
Sbjct: 347 GERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGEC--ACKPGWSGLYCNETCSPGF 404
Query: 543 EGEA---IC---NGASADCPKGVC 560
GEA IC NGA D G C
Sbjct: 405 YGEACQQICSCQNGADCDSVTGKC 428
>AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.
Length = 1117
Score = 35.5 bits (78), Expect = 0.59
Identities = 35/136 (25%), Positives = 53/136 (38%), Gaps = 6/136 (4%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GHN+G HD C G + LM + + + N +S CS I L +
Sbjct: 402 AHEIGHNFGMNHDGIGNSCG-TKGHGAAKLMAAHITA--NTNPFSWSACSRDYITSFLDS 458
Query: 462 KSGRCF-SEPEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRK-NQGAVCSDKNS 519
G C +EP + V G+ DA + CK + + C K++
Sbjct: 459 GRGTCLDNEPPKRDFLYPAVAPGQVYDAD-EQCRFQYGATSRQCKYGEVCRELWCLSKSN 517
Query: 520 PCCAGCVFAPPGLVCR 535
C + A G +C+
Sbjct: 518 RCVTNSIPAAEGTLCQ 533
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 35.5 bits (78), Expect = 0.59
Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 8/84 (9%)
Query: 483 GEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSAC 542
GE C+A L + CDK C C + C C GL C E
Sbjct: 347 GERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGEC--ACKPGWSGLYCNETCSPGF 404
Query: 543 EGEA---IC---NGASADCPKGVC 560
GEA IC NGA D G C
Sbjct: 405 YGEACQQICSCQNGADCDSVTGKC 428
>BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.
Length = 1509
Score = 34.7 bits (76), Expect = 1.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G +HD +C P Y+M YD +S CS I + L
Sbjct: 391 AHELGHSFGIQHDGKENDCEPVGRH--PYIMSRQ--LQYDPTPLTWSKCSEEYITRFLDR 446
Query: 462 KSGRCFSE 469
G C +
Sbjct: 447 GWGFCLDD 454
>AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and
metalloprotease (reprolysin type) with thrombospondin ty
protein.
Length = 1593
Score = 34.7 bits (76), Expect = 1.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G +HD +C P Y+M YD +S CS I + L
Sbjct: 391 AHELGHSFGIQHDGKENDCEPVGRH--PYIMSRQ--LQYDPTPLTWSKCSEEYITRFLDR 446
Query: 462 KSGRCFSE 469
G C +
Sbjct: 447 GWGFCLDD 454
>DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 34.3 bits (75), Expect = 1.4
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G EHD +P + G S + S +SPCS R + +L A
Sbjct: 223 AHEIGHSFGLEHDG-----APGSGCGPSGHVMA-SDGAAPRAGLAWSPCSRRQLLSLLSA 276
Query: 462 KSGRCFSEP 470
RC +P
Sbjct: 277 GRARCVWDP 285
>AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand
factor-cleaving protease precursor protein.
Length = 1427
Score = 34.3 bits (75), Expect = 1.4
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G EHD +P + G S + S +SPCS R + +L A
Sbjct: 223 AHEIGHSFGLEHDG-----APGSGCGPSGHVMA-SDGAAPRAGLAWSPCSRRQLLSLLSA 276
Query: 462 KSGRCFSEP 470
RC +P
Sbjct: 277 GRARCVWDP 285
>AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase
with thrombospondin type 1 motif, 13 protein.
Length = 1371
Score = 34.3 bits (75), Expect = 1.4
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G EHD +P + G S + S +SPCS R + +L A
Sbjct: 223 AHEIGHSFGLEHDG-----APGSGCGPSGHVMA-SDGAAPRAGLAWSPCSRRQLLSLLSA 276
Query: 462 KSGRCFSEP 470
RC +P
Sbjct: 277 GRARCVWDP 285
>AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase
with thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 34.3 bits (75), Expect = 1.4
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G EHD +P + G S + S +SPCS R + +L A
Sbjct: 223 AHEIGHSFGLEHDG-----APGSGCGPSGHVMA-SDGAAPRAGLAWSPCSRRQLLSLLSA 276
Query: 462 KSGRCFSEP 470
RC +P
Sbjct: 277 GRARCVWDP 285
>AL158826-24|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase
with thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 34.3 bits (75), Expect = 1.4
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G EHD +P + G S + S +SPCS R + +L A
Sbjct: 223 AHEIGHSFGLEHDG-----APGSGCGPSGHVMA-SDGAAPRAGLAWSPCSRRQLLSLLSA 276
Query: 462 KSGRCFSEP 470
RC +P
Sbjct: 277 GRARCVWDP 285
>AL158826-22|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase
with thrombospondin type 1 motif, 13 protein.
Length = 1371
Score = 34.3 bits (75), Expect = 1.4
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G EHD +P + G S + S +SPCS R + +L A
Sbjct: 223 AHEIGHSFGLEHDG-----APGSGCGPSGHVMA-SDGAAPRAGLAWSPCSRRQLLSLLSA 276
Query: 462 KSGRCFSEP 470
RC +P
Sbjct: 277 GRARCVWDP 285
>AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, variant
2 protein.
Length = 1371
Score = 34.3 bits (75), Expect = 1.4
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G EHD +P + G S + S +SPCS R + +L A
Sbjct: 223 AHEIGHSFGLEHDG-----APGSGCGPSGHVMA-SDGAAPRAGLAWSPCSRRQLLSLLSA 276
Query: 462 KSGRCFSEP 470
RC +P
Sbjct: 277 GRARCVWDP 285
>AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.
Length = 1427
Score = 34.3 bits (75), Expect = 1.4
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G EHD +P + G S + S +SPCS R + +L A
Sbjct: 223 AHEIGHSFGLEHDG-----APGSGCGPSGHVMA-SDGAAPRAGLAWSPCSRRQLLSLLSA 276
Query: 462 KSGRCFSEP 470
RC +P
Sbjct: 277 GRARCVWDP 285
>AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand
factor-cleaving protease protein.
Length = 1427
Score = 34.3 bits (75), Expect = 1.4
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH++G EHD +P + G S + S +SPCS R + +L A
Sbjct: 223 AHEIGHSFGLEHDG-----APGSGCGPSGHVMA-SDGAAPRAGLAWSPCSRRQLLSLLSA 276
Query: 462 KSGRCFSEP 470
RC +P
Sbjct: 277 GRARCVWDP 285
>AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein.
Length = 2551
Score = 33.5 bits (73), Expect = 2.4
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 11/83 (13%)
Query: 481 EGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC---SDKNSPCCAGCVFAPPGLVCREA 537
+G +CD G G ++ + NC + A C SD + C F G +C
Sbjct: 1413 DGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTIC--T 1470
Query: 538 AHSACEGEAICNG---ASADCPK 557
A +ACE I NG A ADC +
Sbjct: 1471 AINACE---ISNGGCSAKADCKR 1490
>AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for
endocytosis precursor protein.
Length = 1416
Score = 33.5 bits (73), Expect = 2.4
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 11/83 (13%)
Query: 481 EGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC---SDKNSPCCAGCVFAPPGLVCREA 537
+G +CD G G ++ + NC + A C SD + C F G +C
Sbjct: 278 DGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTIC--T 335
Query: 538 AHSACEGEAICNG---ASADCPK 557
A +ACE I NG A ADC +
Sbjct: 336 AINACE---ISNGGCSAKADCKR 355
>AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein.
Length = 1055
Score = 33.5 bits (73), Expect = 2.4
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 11/83 (13%)
Query: 481 EGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC---SDKNSPCCAGCVFAPPGLVCREA 537
+G +CD G G ++ + NC + A C SD + C F G +C
Sbjct: 846 DGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTIC--T 903
Query: 538 AHSACEGEAICNG---ASADCPK 557
A +ACE I NG A ADC +
Sbjct: 904 AINACE---ISNGGCSAKADCKR 923
>AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein.
Length = 1736
Score = 33.5 bits (73), Expect = 2.4
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 11/83 (13%)
Query: 481 EGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC---SDKNSPCCAGCVFAPPGLVCREA 537
+G +CD G G ++ + NC + A C SD + C F G +C
Sbjct: 598 DGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTIC--T 655
Query: 538 AHSACEGEAICNG---ASADCPK 557
A +ACE I NG A ADC +
Sbjct: 656 AINACE---ISNGGCSAKADCKR 675
>AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein.
Length = 1192
Score = 33.5 bits (73), Expect = 2.4
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 11/83 (13%)
Query: 481 EGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC---SDKNSPCCAGCVFAPPGLVCREA 537
+G +CD G G ++ + NC + A C SD + C F G +C
Sbjct: 54 DGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTIC--T 111
Query: 538 AHSACEGEAICNG---ASADCPK 557
A +ACE I NG A ADC +
Sbjct: 112 AINACE---ISNGGCSAKADCKR 131
>AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein.
Length = 2551
Score = 33.5 bits (73), Expect = 2.4
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 11/83 (13%)
Query: 481 EGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC---SDKNSPCCAGCVFAPPGLVCREA 537
+G +CD G G ++ + NC + A C SD + C F G +C
Sbjct: 1413 DGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTIC--T 1470
Query: 538 AHSACEGEAICNG---ASADCPK 557
A +ACE I NG A ADC +
Sbjct: 1471 AINACE---ISNGGCSAKADCKR 1490
>AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein.
Length = 2551
Score = 33.5 bits (73), Expect = 2.4
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 11/83 (13%)
Query: 481 EGGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVC---SDKNSPCCAGCVFAPPGLVCREA 537
+G +CD G G ++ + NC + A C SD + C F G +C
Sbjct: 1413 DGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTIC--T 1470
Query: 538 AHSACEGEAICNG---ASADCPK 557
A +ACE I NG A ADC +
Sbjct: 1471 AINACE---ISNGGCSAKADCKR 1490
>BC127016-1|AAI27017.1| 259|Homo sapiens KRTAP10-8 protein protein.
Length = 259
Score = 33.1 bits (72), Expect = 3.1
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 13/75 (17%)
Query: 498 MCCDKNCKLRKNQGAVCSDKNSPCC-------AGCVFAPPGLVCREAAHSACEG---EAI 547
+CC NC ++CS +SPCC A C F+P C C+ +
Sbjct: 122 VCCKSNCCKPVCCVSICSGASSPCCQQSSCQSACCTFSPCQQAC--CVPICCKPICCVPV 179
Query: 548 CNGASA-DCPKGVCE 561
C+GAS+ C K C+
Sbjct: 180 CSGASSLCCQKSSCQ 194
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 33.1 bits (72), Expect = 3.1
Identities = 35/143 (24%), Positives = 52/143 (36%), Gaps = 12/143 (8%)
Query: 415 PDVAECSPAASQGGSYLMYTYSVSGYDVN--NKRFSPCSLRSIRKVLQAKSGRCFSEPEE 472
P+V+ C AAS+ G + + SG +N N + C L + + C S P +
Sbjct: 1101 PNVS-CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQ 1159
Query: 473 SFCGNLRVEGGEECDA--GLLGTE---DNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVF 527
GG C+ G G + D C ++ C+ G C D + C
Sbjct: 1160 HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQ----NGGTCIDLVNHFKCSCPP 1215
Query: 528 APPGLVCREAAHSACEGEAICNG 550
GL+C E G NG
Sbjct: 1216 GTRGLLCEENIDDCARGPHCLNG 1238
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 33.1 bits (72), Expect = 3.1
Identities = 35/143 (24%), Positives = 52/143 (36%), Gaps = 12/143 (8%)
Query: 415 PDVAECSPAASQGGSYLMYTYSVSGYDVN--NKRFSPCSLRSIRKVLQAKSGRCFSEPEE 472
P+V+ C AAS+ G + + SG +N N + C L + + C S P +
Sbjct: 1101 PNVS-CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQ 1159
Query: 473 SFCGNLRVEGGEECDA--GLLGTE---DNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVF 527
GG C+ G G + D C ++ C+ G C D + C
Sbjct: 1160 HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQ----NGGTCIDLVNHFKCSCPP 1215
Query: 528 APPGLVCREAAHSACEGEAICNG 550
GL+C E G NG
Sbjct: 1216 GTRGLLCEENIDDCARGPHCLNG 1238
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 33.1 bits (72), Expect = 3.1
Identities = 35/143 (24%), Positives = 52/143 (36%), Gaps = 12/143 (8%)
Query: 415 PDVAECSPAASQGGSYLMYTYSVSGYDVN--NKRFSPCSLRSIRKVLQAKSGRCFSEPEE 472
P+V+ C AAS+ G + + SG +N N + C L + + C S P +
Sbjct: 1101 PNVS-CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQ 1159
Query: 473 SFCGNLRVEGGEECDA--GLLGTE---DNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVF 527
GG C+ G G + D C ++ C+ G C D + C
Sbjct: 1160 HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQ----NGGTCIDLVNHFKCSCPP 1215
Query: 528 APPGLVCREAAHSACEGEAICNG 550
GL+C E G NG
Sbjct: 1216 GTRGLLCEENIDDCARGPHCLNG 1238
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 33.1 bits (72), Expect = 3.1
Identities = 35/143 (24%), Positives = 52/143 (36%), Gaps = 12/143 (8%)
Query: 415 PDVAECSPAASQGGSYLMYTYSVSGYDVN--NKRFSPCSLRSIRKVLQAKSGRCFSEPEE 472
P+V+ C AAS+ G + + SG +N N + C L + + C S P +
Sbjct: 1101 PNVS-CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQ 1159
Query: 473 SFCGNLRVEGGEECDA--GLLGTE---DNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVF 527
GG C+ G G + D C ++ C+ G C D + C
Sbjct: 1160 HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQ----NGGTCIDLVNHFKCSCPP 1215
Query: 528 APPGLVCREAAHSACEGEAICNG 550
GL+C E G NG
Sbjct: 1216 GTRGLLCEENIDDCARGPHCLNG 1238
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 33.1 bits (72), Expect = 3.1
Identities = 35/143 (24%), Positives = 52/143 (36%), Gaps = 12/143 (8%)
Query: 415 PDVAECSPAASQGGSYLMYTYSVSGYDVN--NKRFSPCSLRSIRKVLQAKSGRCFSEPEE 472
P+V+ C AAS+ G + + SG +N N + C L + + C S P +
Sbjct: 1101 PNVS-CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQ 1159
Query: 473 SFCGNLRVEGGEECDA--GLLGTE---DNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVF 527
GG C+ G G + D C ++ C+ G C D + C
Sbjct: 1160 HGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQ----NGGTCIDLVNHFKCSCPP 1215
Query: 528 APPGLVCREAAHSACEGEAICNG 550
GL+C E G NG
Sbjct: 1216 GTRGLLCEENIDDCARGPHCLNG 1238
>AB076355-1|BAD01542.1| 259|Homo sapiens keratin associated protein
protein.
Length = 259
Score = 33.1 bits (72), Expect = 3.1
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 13/75 (17%)
Query: 498 MCCDKNCKLRKNQGAVCSDKNSPCC-------AGCVFAPPGLVCREAAHSACEG---EAI 547
+CC NC ++CS +SPCC A C F+P C C+ +
Sbjct: 122 VCCKSNCCKPVCCVSICSGASSPCCQQSSCQSACCTFSPCQQAC--CVPICCKPICCVPV 179
Query: 548 CNGASA-DCPKGVCE 561
C+GAS+ C K C+
Sbjct: 180 CSGASSLCCQKSSCQ 194
>BC008720-1|AAH08720.1| 422|Homo sapiens cysteine-rich with
EGF-like domains 1 protein.
Length = 422
Score = 32.7 bits (71), Expect = 4.2
Identities = 15/49 (30%), Positives = 17/49 (34%)
Query: 513 VCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGVCE 561
+CSD CC F P L C C G C G G C+
Sbjct: 134 LCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCD 182
>AY358363-1|AAQ88729.1| 420|Homo sapiens CRELD1 protein.
Length = 420
Score = 32.7 bits (71), Expect = 4.2
Identities = 15/49 (30%), Positives = 17/49 (34%)
Query: 513 VCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGVCE 561
+CSD CC F P L C C G C G G C+
Sbjct: 134 LCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCD 182
>AF452623-1|AAM75206.1| 420|Homo sapiens cysteine-rich with
EGF-like domains 1 protein.
Length = 420
Score = 32.7 bits (71), Expect = 4.2
Identities = 15/49 (30%), Positives = 17/49 (34%)
Query: 513 VCSDKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNGASADCPKGVCE 561
+CSD CC F P L C C G C G G C+
Sbjct: 134 LCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCD 182
>X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein.
Length = 2201
Score = 32.3 bits (70), Expect = 5.5
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 462 KSGRCFSEPEESFCGNLR---VEGGEECDAGLLGTEDNDMCCDKNCKLR-KNQGAVCSDK 517
K C SEPE +LR ++G CD G G + + + C +C + K VC
Sbjct: 181 KGPNC-SEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICF 239
Query: 518 NSPCCAGCVFAPPGLVCREAAHSACEGEAICNG--ASADCPKGVC 560
A C + C E + +G +C+ A DC K +C
Sbjct: 240 EGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLC 284
>M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein.
Length = 2203
Score = 32.3 bits (70), Expect = 5.5
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 462 KSGRCFSEPEESFCGNLR---VEGGEECDAGLLGTEDNDMCCDKNCKLR-KNQGAVCSDK 517
K C SEPE +LR ++G CD G G + + + C +C + K VC
Sbjct: 181 KGPNC-SEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICF 239
Query: 518 NSPCCAGCVFAPPGLVCREAAHSACEGEAICNG--ASADCPKGVC 560
A C + C E + +G +C+ A DC K +C
Sbjct: 240 EGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLC 284
>BC053863-1|AAH53863.1| 709|Homo sapiens YTH domain containing 1
protein.
Length = 709
Score = 32.3 bits (70), Expect = 5.5
Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
Query: 160 KEGKELEDDSDDVQEEYDIELKHEQLEKEKY-LDQTNSYHPANEADTSND 208
+E +E+++D ++ +EE + E + E+ E+E+Y D+ + N+ DT ++
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
>BC041119-1|AAH41119.1| 727|Homo sapiens YTH domain containing 1
protein.
Length = 727
Score = 32.3 bits (70), Expect = 5.5
Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
Query: 160 KEGKELEDDSDDVQEEYDIELKHEQLEKEKY-LDQTNSYHPANEADTSND 208
+E +E+++D ++ +EE + E + E+ E+E+Y D+ + N+ DT ++
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
>AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachion)
protein.
Length = 2201
Score = 32.3 bits (70), Expect = 5.5
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 462 KSGRCFSEPEESFCGNLR---VEGGEECDAGLLGTEDNDMCCDKNCKLR-KNQGAVCSDK 517
K C SEPE +LR ++G CD G G + + + C +C + K VC
Sbjct: 181 KGPNC-SEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICF 239
Query: 518 NSPCCAGCVFAPPGLVCREAAHSACEGEAICNG--ASADCPKGVC 560
A C + C E + +G +C+ A DC K +C
Sbjct: 240 EGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLC 284
>AK056430-1|BAB71181.1| 658|Homo sapiens protein ( Homo sapiens
cDNA FLJ31868 fis, clone NT2RP7001962, highly similar to
Rattus norvegicus YT521 mRNA for RNA splicing-related
protein. ).
Length = 658
Score = 32.3 bits (70), Expect = 5.5
Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
Query: 160 KEGKELEDDSDDVQEEYDIELKHEQLEKEKY-LDQTNSYHPANEADTSND 208
+E +E+++D ++ +EE + E + E+ E+E+Y D+ + N+ DT ++
Sbjct: 169 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 218
>AC074378-1|AAY41024.1| 658|Homo sapiens unknown protein.
Length = 658
Score = 32.3 bits (70), Expect = 5.5
Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
Query: 160 KEGKELEDDSDDVQEEYDIELKHEQLEKEKY-LDQTNSYHPANEADTSND 208
+E +E+++D ++ +EE + E + E+ E+E+Y D+ + N+ DT ++
Sbjct: 169 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 218
>AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein
protein.
Length = 2233
Score = 32.3 bits (70), Expect = 5.5
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 462 KSGRCFSEPEESFCGNLR---VEGGEECDAGLLGTEDNDMCCDKNCKLR-KNQGAVCSDK 517
K C SEPE +LR ++G CD G G + + + C +C + K VC
Sbjct: 213 KGPNC-SEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICF 271
Query: 518 NSPCCAGCVFAPPGLVCREAAHSACEGEAICNG--ASADCPKGVC 560
A C + C E + +G +C+ A DC K +C
Sbjct: 272 EGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLC 316
>AB209515-1|BAD92752.1| 847|Homo sapiens a disintegrin-like and
metalloprotease (reprolysin type) with thrombospondin ty
protein.
Length = 847
Score = 31.9 bits (69), Expect = 7.3
Identities = 39/142 (27%), Positives = 54/142 (38%), Gaps = 18/142 (12%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQA 461
AHE GH +G HD V A Q + LM + N +S CS I L +
Sbjct: 145 AHEIGHTFGMNHD-GVGNSCGARGQDPAKLMAAHIT--MKTNPFVWSSCSRDYITSFLDS 201
Query: 462 KSGRCFSE--PEESFCGNLRVEGGEECDAGLLGTEDNDMCCDKNCKLRK-NQGAVCSD-- 516
G C + P + F V G+ DA D K R+ G VCS+
Sbjct: 202 GLGLCLNNRPPRQDFV-YPTVAPGQAYDA------DEQCRFQHGVKSRQCKYGEVCSELW 254
Query: 517 ---KNSPCCAGCVFAPPGLVCR 535
K++ C + A G +C+
Sbjct: 255 CLSKSNRCITNSIPAAEGTLCQ 276
>AB076353-1|BAD01540.1| 365|Homo sapiens keratin associated protein
protein.
Length = 365
Score = 31.9 bits (69), Expect = 7.3
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 9/69 (13%)
Query: 498 MCC-DKNCKLRKN-QGAVCSDKNSPCCAGC---VFAPPGLVCREAAHSACEGEAICNGAS 552
+CC D +C + + Q A C+ +SPC C V P VC + S C+ + + S
Sbjct: 128 VCCGDSSCCQQSSCQSACCT--SSPCQQACCVPVCCKP--VCSGISSSCCQQSSCVSCVS 183
Query: 553 ADCPKGVCE 561
+ C + VCE
Sbjct: 184 SPCCQAVCE 192
>AB076348-1|BAD01535.1| 255|Homo sapiens keratin associated protein
protein.
Length = 255
Score = 31.9 bits (69), Expect = 7.3
Identities = 18/78 (23%), Positives = 32/78 (41%), Gaps = 3/78 (3%)
Query: 486 CDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSACEGE 545
C + + D C + C+L + C+ +PC V P V +ACE
Sbjct: 9 CSSACTNSWQVDDCPESCCELPCGTPSCCAP--APCLT-LVCTPVSCVSSPCCQAACEPS 65
Query: 546 AICNGASADCPKGVCEKT 563
A +G ++ C C+++
Sbjct: 66 ACQSGCTSSCTPSCCQQS 83
>X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein.
Length = 2199
Score = 31.5 bits (68), Expect = 9.6
Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 462 KSGRCFSEPEESFCGNLR---VEGGEECDAGLLGTEDNDMCCDKNCKLR---KNQGAVCS 515
K C SEPE +LR ++G CD G G + + + C +C + N +C
Sbjct: 181 KGPNC-SEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICF 239
Query: 516 DKNSPCCAGCVFAPPGLVCREAAHSACEGEAICNG--ASADCPKGVC 560
+ + C+ + P C E + +G +C+ A DC K +C
Sbjct: 240 EGYAADCSREICPVP---CSEEHGTCVDGLCVCHDGFAGDDCNKPLC 283
>BC125049-1|AAI25050.1| 401|Homo sapiens keratin associated protein
10-4 protein.
Length = 401
Score = 31.5 bits (68), Expect = 9.6
Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 9/69 (13%)
Query: 498 MCC-DKNCKLRKN-QGAVCSDKNSPCCAGC---VFAPPGLVCREAAHSACEGEAICNGAS 552
+CC D +C + + Q A C+ +SPC C + P VC + S C+ + + S
Sbjct: 128 VCCGDSSCCQQSSCQSACCT--SSPCQQACCVPICCKP--VCSGISSSCCQQSSCVSCVS 183
Query: 553 ADCPKGVCE 561
+ C + VCE
Sbjct: 184 SPCCQAVCE 192
>BC125048-1|AAI25049.1| 401|Homo sapiens keratin associated protein
10-4 protein.
Length = 401
Score = 31.5 bits (68), Expect = 9.6
Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 9/69 (13%)
Query: 498 MCC-DKNCKLRKN-QGAVCSDKNSPCCAGC---VFAPPGLVCREAAHSACEGEAICNGAS 552
+CC D +C + + Q A C+ +SPC C + P VC + S C+ + + S
Sbjct: 128 VCCGDSSCCQQSSCQSACCT--SSPCQQACCVPICCKP--VCSGISSSCCQQSSCVSCVS 183
Query: 553 ADCPKGVCE 561
+ C + VCE
Sbjct: 184 SPCCQAVCE 192
>BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 18 protein.
Length = 1221
Score = 31.5 bits (68), Expect = 9.6
Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 11/75 (14%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRF--SPCSLRSIRKVL 459
AHE GHN+G HD E +P G+ + T ++G NN F S CS + ++K L
Sbjct: 435 AHESGHNFGMIHD---GEGNPCRKAEGNIMSPT--LTG---NNGVFSWSSCSRQYLKKFL 486
Query: 460 QAKSGRCF-SEPEES 473
C EP+++
Sbjct: 487 STPQAGCLVDEPKQA 501
>BC004107-1|AAH04107.1| 344|Homo sapiens follistatin protein.
Length = 344
Score = 31.5 bits (68), Expect = 9.6
Identities = 31/133 (23%), Positives = 49/133 (36%), Gaps = 9/133 (6%)
Query: 422 PAASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVE 481
PA+S+ YL V+ + R + C L R + A G+C C +++
Sbjct: 199 PASSE--QYLCGNDGVTYSSACHLRKATCLLG--RSIGLAYEGKCIKAKS---CEDIQCT 251
Query: 482 GGEECDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHSA 541
GG++C CD+ C K+ VC+ N+ + C A C
Sbjct: 252 GGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASEC--AMKEAACSSGVLLE 309
Query: 542 CEGEAICNGASAD 554
+ CN S D
Sbjct: 310 VKHSGSCNSISED 322
>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 3 protein.
Length = 2809
Score = 31.5 bits (68), Expect = 9.6
Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 486 CDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHS-ACEG 544
C G C C+ +G CS N CA AP V R + S +C
Sbjct: 68 CCPGWRTFPGRSQCVVPICRRACGEG-FCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMN 126
Query: 545 EAICNGASADCPKG----VCEKTIQD 566
C GAS C KG VC + I D
Sbjct: 127 GGTCRGASCLCQKGYTGTVCGQPICD 152
>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 2 protein.
Length = 2809
Score = 31.5 bits (68), Expect = 9.6
Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 486 CDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHS-ACEG 544
C G C C+ +G CS N CA AP V R + S +C
Sbjct: 68 CCPGWRTFPGRSQCVVPICRRACGEG-FCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMN 126
Query: 545 EAICNGASADCPKG----VCEKTIQD 566
C GAS C KG VC + I D
Sbjct: 127 GGTCRGASCLCQKGYTGTVCGQPICD 152
>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 1 protein.
Length = 2809
Score = 31.5 bits (68), Expect = 9.6
Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 486 CDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHS-ACEG 544
C G C C+ +G CS N CA AP V R + S +C
Sbjct: 68 CCPGWRTFPGRSQCVVPICRRACGEG-FCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMN 126
Query: 545 EAICNGASADCPKG----VCEKTIQD 566
C GAS C KG VC + I D
Sbjct: 127 GGTCRGASCLCQKGYTGTVCGQPICD 152
>AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.
Length = 1081
Score = 31.5 bits (68), Expect = 9.6
Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 11/75 (14%)
Query: 402 AHEFGHNWGSEHDPDVAECSPAASQGGSYLMYTYSVSGYDVNNKRF--SPCSLRSIRKVL 459
AHE GHN+G HD E +P G+ + T ++G NN F S CS + ++K L
Sbjct: 434 AHESGHNFGMIHD---GEGNPCRKAEGNIMSPT--LTG---NNGVFSWSSCSRQYLKKFL 485
Query: 460 QAKSGRCF-SEPEES 473
C EP+++
Sbjct: 486 STPQAGCLVDEPKQA 500
>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 31.5 bits (68), Expect = 9.6
Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 486 CDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHS-ACEG 544
C G C C+ +G CS N CA AP V R + S +C
Sbjct: 68 CCPGWRTFPGRSQCVVPICRRACGEG-FCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMN 126
Query: 545 EAICNGASADCPKG----VCEKTIQD 566
C GAS C KG VC + I D
Sbjct: 127 GGTCRGASCLCQKGYTGTVCGQPICD 152
>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 31.5 bits (68), Expect = 9.6
Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 486 CDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHS-ACEG 544
C G C C+ +G CS N CA AP V R + S +C
Sbjct: 68 CCPGWRTFPGRSQCVVPICRRACGEG-FCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMN 126
Query: 545 EAICNGASADCPKG----VCEKTIQD 566
C GAS C KG VC + I D
Sbjct: 127 GGTCRGASCLCQKGYTGTVCGQPICD 152
>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 31.5 bits (68), Expect = 9.6
Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 486 CDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHS-ACEG 544
C G C C+ +G CS N CA AP V R + S +C
Sbjct: 68 CCPGWRTFPGRSQCVVPICRRACGEG-FCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMN 126
Query: 545 EAICNGASADCPKG----VCEKTIQD 566
C GAS C KG VC + I D
Sbjct: 127 GGTCRGASCLCQKGYTGTVCGQPICD 152
>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 31.5 bits (68), Expect = 9.6
Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 486 CDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHS-ACEG 544
C G C C+ +G CS N CA AP V R + S +C
Sbjct: 68 CCPGWRTFPGRSQCVVPICRRACGEG-FCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMN 126
Query: 545 EAICNGASADCPKG----VCEKTIQD 566
C GAS C KG VC + I D
Sbjct: 127 GGTCRGASCLCQKGYTGTVCGQPICD 152
>AB076351-1|BAD01538.1| 401|Homo sapiens keratin associated protein
protein.
Length = 401
Score = 31.5 bits (68), Expect = 9.6
Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 9/69 (13%)
Query: 498 MCC-DKNCKLRKN-QGAVCSDKNSPCCAGC---VFAPPGLVCREAAHSACEGEAICNGAS 552
+CC D +C + + Q A C+ +SPC C + P VC + S C+ + + S
Sbjct: 128 VCCGDSSCCQQSSCQSACCT--SSPCQQACCVPICCKP--VCSGISSSCCQQSSCVSCVS 183
Query: 553 ADCPKGVCE 561
+ C + VCE
Sbjct: 184 SPCCQAVCE 192
>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
Length = 2816
Score = 31.5 bits (68), Expect = 9.6
Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 486 CDAGLLGTEDNDMCCDKNCKLRKNQGAVCSDKNSPCCAGCVFAPPGLVCREAAHS-ACEG 544
C G C C+ +G CS N CA AP V R + S +C
Sbjct: 75 CCPGWRTFPGRSQCVVPICRRACGEG-FCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMN 133
Query: 545 EAICNGASADCPKG----VCEKTIQD 566
C GAS C KG VC + I D
Sbjct: 134 GGTCRGASCLCQKGYTGTVCGQPICD 159
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.136 0.420
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,738,154
Number of Sequences: 224733
Number of extensions: 4753886
Number of successful extensions: 21357
Number of sequences better than 10.0: 203
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 94
Number of HSP's that attempted gapping in prelim test: 20712
Number of HSP's gapped (non-prelim): 387
length of query: 648
length of database: 73,234,838
effective HSP length: 95
effective length of query: 553
effective length of database: 51,885,203
effective search space: 28692517259
effective search space used: 28692517259
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 68 (31.5 bits)
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