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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001427-TA|BGIBMGA001427-PA|undefined
         (586 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC109061-1|AAI09062.1|  550|Homo sapiens DET1 protein protein.        685   0.0  
BC109060-1|AAI09061.1|  550|Homo sapiens DET1 protein protein.        685   0.0  
BC001242-1|AAH01242.2|  361|Homo sapiens DET1 protein protein.        487   e-137
AK000965-1|BAA91447.1|  268|Homo sapiens protein ( Homo sapiens ...   379   e-104
BX649632-1|CAI18774.1|  334|Homo sapiens WD repeat domain 5 prot...    35   0.92 
BC001635-1|AAH01635.1|  334|Homo sapiens WD repeat domain 5 prot...    35   0.92 
AK000552-1|BAA91248.1|  334|Homo sapiens protein ( Homo sapiens ...    35   0.92 
AJ011376-1|CAB66159.1|  362|Homo sapiens hypothetical protein pr...    35   0.92 
CR457279-1|CAG33560.1|  330|Homo sapiens WDR5B protein.                33   2.1  
BC043494-1|AAH43494.1|  330|Homo sapiens WD repeat domain 5B pro...    33   2.1  
AK002149-1|BAA92110.1|  330|Homo sapiens protein ( Homo sapiens ...    33   2.1  
AF082196-1|AAC36104.1|  119|Homo sapiens anti-pneumococcal/anti-...    32   6.5  

>BC109061-1|AAI09062.1|  550|Homo sapiens DET1 protein protein.
          Length = 550

 Score =  685 bits (1693), Expect = 0.0
 Identities = 330/560 (58%), Positives = 424/560 (75%), Gaps = 28/560 (5%)

Query: 31  IVPRKIKPQNIVIRLMEREIHGSRKPGSHFHVVREFYQNVFPNLTIVNVEKPPCFLRKFS 90
           I PR+I+ QN++ RL  R I  S K G+H+H VR F+QNVFPN T+VNVEKPPCFLRKFS
Sbjct: 8   IKPRRIQNQNVIHRLERRRI-SSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFS 66

Query: 91  PDGKHFIAFSADQTSLEIYEYRGASSAGDLVAGYPTDLLNADADAHH-RIRTHIFYRFFK 149
           PDG++FIAFS+DQTSLEIYEY+G  +A DL+ GY  ++L+   D     IR  +F RFF 
Sbjct: 67  PDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVNIRGRLFERFFV 126

Query: 150 PKFTVNVCQQRDIRSDRLGNMPVMEQQLNRECSLFTEDGRYVIVGSAAHIPDDLRPHFYH 209
                NV    +               LNRECSLFT+D R VIVGSAA++PD+  P F+ 
Sbjct: 127 LLHITNVAANGE--------------HLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFFE 172

Query: 210 IHSNNEAVTPTIRSPLEDYSLHLVDLHQGKLCDTKHFRIDKIYLSHNQGIYLYKEVLAVL 269
           ++ N+E+VTP  RSPLEDYSLH++DLH G+LCDT+ F+ DK+ LSHNQG+YLYK +LA+L
Sbjct: 173 VYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAIL 232

Query: 270 SVQHQTIHLYQIV-EGMLIEIRKIGRYCYDDDPFIVSSIIGKSINEK------PFHEETI 322
           SVQ QTIH++Q+  EG  I++R IGR+CY+DD   VS++  +   +       PF +  I
Sbjct: 233 SVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFI 292

Query: 323 NSLKHRILVFLFKRAKKITDETGDPLELRKFYKYFDMFKSLRMWKMQLLDEDHLFIKYAS 382
           NSLKHR+LV+L++RA    ++ G  +  R+F++YFD  + LRMWKMQLLDE+HLFIKY S
Sbjct: 293 NSLKHRLLVYLWRRA----EQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTS 348

Query: 383 EEVVTLRVAEPNSQSSFFVIYNISQSKVLEIYENTSEALLQLFENYCDCFRNARLCADSQ 442
           E+VVTLRV +P SQ+SFFV+YN+  ++V+ ++ENTS+ LL+LFEN+CD FRNA L ++ Q
Sbjct: 349 EDVVTLRVTDP-SQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQ 407

Query: 443 FTCSPSNNLYARLTQQRFKQTIVRAIYGGRTEATKRILAQLPISAQSYSGSPYLDLGLFS 502
           F CS S+N +AR  Q+RFK TI+ A YGG TEA +R+L QLPISAQSYSGSPYLDL LFS
Sbjct: 408 FPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFS 467

Query: 503 YDDKWVSVMERPKAYGEYPIRFYARDSGLLKFKIYAGVLGQSVPPSARRLVAFTFHPTDP 562
           YDDKWVSVMERPK  G++PIRFYARDSGLLKF+I AG+LG+ +  + RRLVAFTFHP +P
Sbjct: 468 YDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEP 527

Query: 563 FAISVQRTNSEYIVNFHIRN 582
           FAISVQRTN+EY+VNFH+R+
Sbjct: 528 FAISVQRTNAEYVVNFHMRH 547


>BC109060-1|AAI09061.1|  550|Homo sapiens DET1 protein protein.
          Length = 550

 Score =  685 bits (1693), Expect = 0.0
 Identities = 330/560 (58%), Positives = 424/560 (75%), Gaps = 28/560 (5%)

Query: 31  IVPRKIKPQNIVIRLMEREIHGSRKPGSHFHVVREFYQNVFPNLTIVNVEKPPCFLRKFS 90
           I PR+I+ QN++ RL  R I  S K G+H+H VR F+QNVFPN T+VNVEKPPCFLRKFS
Sbjct: 8   IKPRRIQNQNVIHRLERRRI-SSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFS 66

Query: 91  PDGKHFIAFSADQTSLEIYEYRGASSAGDLVAGYPTDLLNADADAHH-RIRTHIFYRFFK 149
           PDG++FIAFS+DQTSLEIYEY+G  +A DL+ GY  ++L+   D     IR  +F RFF 
Sbjct: 67  PDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVNIRGRLFERFFV 126

Query: 150 PKFTVNVCQQRDIRSDRLGNMPVMEQQLNRECSLFTEDGRYVIVGSAAHIPDDLRPHFYH 209
                NV    +               LNRECSLFT+D R VIVGSAA++PD+  P F+ 
Sbjct: 127 LLHITNVAANGE--------------HLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFFE 172

Query: 210 IHSNNEAVTPTIRSPLEDYSLHLVDLHQGKLCDTKHFRIDKIYLSHNQGIYLYKEVLAVL 269
           ++ N+E+VTP  RSPLEDYSLH++DLH G+LCDT+ F+ DK+ LSHNQG+YLYK +LA+L
Sbjct: 173 VYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAIL 232

Query: 270 SVQHQTIHLYQIV-EGMLIEIRKIGRYCYDDDPFIVSSIIGKSINEK------PFHEETI 322
           SVQ QTIH++Q+  EG  I++R IGR+CY+DD   VS++  +   +       PF +  I
Sbjct: 233 SVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFI 292

Query: 323 NSLKHRILVFLFKRAKKITDETGDPLELRKFYKYFDMFKSLRMWKMQLLDEDHLFIKYAS 382
           NSLKHR+LV+L++RA    ++ G  +  R+F++YFD  + LRMWKMQLLDE+HLFIKY S
Sbjct: 293 NSLKHRLLVYLWRRA----EQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTS 348

Query: 383 EEVVTLRVAEPNSQSSFFVIYNISQSKVLEIYENTSEALLQLFENYCDCFRNARLCADSQ 442
           E+VVTLRV +P SQ+SFFV+YN+  ++V+ ++ENTS+ LL+LFEN+CD FRNA L ++ Q
Sbjct: 349 EDVVTLRVTDP-SQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQ 407

Query: 443 FTCSPSNNLYARLTQQRFKQTIVRAIYGGRTEATKRILAQLPISAQSYSGSPYLDLGLFS 502
           F CS S+N +AR  Q+RFK TI+ A YGG TEA +R+L QLPISAQSYSGSPYLDL LFS
Sbjct: 408 FPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFS 467

Query: 503 YDDKWVSVMERPKAYGEYPIRFYARDSGLLKFKIYAGVLGQSVPPSARRLVAFTFHPTDP 562
           YDDKWVSVMERPK  G++PIRFYARDSGLLKF+I AG+LG+ +  + RRLVAFTFHP +P
Sbjct: 468 YDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEP 527

Query: 563 FAISVQRTNSEYIVNFHIRN 582
           FAISVQRTN+EY+VNFH+R+
Sbjct: 528 FAISVQRTNAEYVVNFHMRH 547


>BC001242-1|AAH01242.2|  361|Homo sapiens DET1 protein protein.
          Length = 361

 Score =  487 bits (1202), Expect = e-137
 Identities = 225/363 (61%), Positives = 291/363 (80%), Gaps = 12/363 (3%)

Query: 227 DYSLHLVDLHQGKLCDTKHFRIDKIYLSHNQGIYLYKEVLAVLSVQHQTIHLYQIV-EGM 285
           DYSLH++DLH G+LCDT+ F+ DK+ LSHNQG+YLYK +LA+LSVQ QTIH++Q+  EG 
Sbjct: 1   DYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGT 60

Query: 286 LIEIRKIGRYCYDDDPFIVSSIIGKSINEK------PFHEETINSLKHRILVFLFKRAKK 339
            I++R IGR+CY+DD   VS++  +   +       PF +  INSLKHR+LV+L++RA  
Sbjct: 61  FIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLLVYLWRRA-- 118

Query: 340 ITDETGDPLELRKFYKYFDMFKSLRMWKMQLLDEDHLFIKYASEEVVTLRVAEPNSQSSF 399
             ++ G  +  R+F++YFD  + LRMWKMQLLDE+HLFIKY SE+VVTLRV +P SQ+SF
Sbjct: 119 --EQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDP-SQASF 175

Query: 400 FVIYNISQSKVLEIYENTSEALLQLFENYCDCFRNARLCADSQFTCSPSNNLYARLTQQR 459
           FV+YN+  ++V+ ++ENTS+ LL+LFEN+CD FRNA L ++ QF CS S+N +AR  Q+R
Sbjct: 176 FVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQIQRR 235

Query: 460 FKQTIVRAIYGGRTEATKRILAQLPISAQSYSGSPYLDLGLFSYDDKWVSVMERPKAYGE 519
           FK TI+ A YGG TEA +R+L QLPISAQSYSGSPYLDL LFSYDDKWVSVMERPK  G+
Sbjct: 236 FKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGD 295

Query: 520 YPIRFYARDSGLLKFKIYAGVLGQSVPPSARRLVAFTFHPTDPFAISVQRTNSEYIVNFH 579
           +PIRFYARDSGLLKF+I AG+LG+ +  + RRLVAFTFHP +PFAISVQRTN+EY+VNFH
Sbjct: 296 HPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFH 355

Query: 580 IRN 582
           +R+
Sbjct: 356 MRH 358


>AK000965-1|BAA91447.1|  268|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10103 fis, clone HEMBA1002495, weakly similar to
           LIGHT-MEDIATED DEVELOPMENT PROTEIN DET1. ).
          Length = 268

 Score =  379 bits (933), Expect = e-104
 Identities = 175/267 (65%), Positives = 221/267 (82%), Gaps = 5/267 (1%)

Query: 316 PFHEETINSLKHRILVFLFKRAKKITDETGDPLELRKFYKYFDMFKSLRMWKMQLLDEDH 375
           PF +  INSLKHR+LV+L++RA    ++ G  +  R+F++YFD  + LRMWKMQLLDE+H
Sbjct: 4   PFRDPFINSLKHRLLVYLWRRA----EQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENH 59

Query: 376 LFIKYASEEVVTLRVAEPNSQSSFFVIYNISQSKVLEIYENTSEALLQLFENYCDCFRNA 435
           LFIKY SE+VVTLRV +P SQ+SFFV+YN+  ++V+ ++ENTS+ LL+LFEN+CD FRNA
Sbjct: 60  LFIKYTSEDVVTLRVTDP-SQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNA 118

Query: 436 RLCADSQFTCSPSNNLYARLTQQRFKQTIVRAIYGGRTEATKRILAQLPISAQSYSGSPY 495
            L ++ QF CS S+N +AR  Q+RFK TI+ A YGG TEA +R+L QLPISAQSYSGSPY
Sbjct: 119 TLHSEVQFPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPY 178

Query: 496 LDLGLFSYDDKWVSVMERPKAYGEYPIRFYARDSGLLKFKIYAGVLGQSVPPSARRLVAF 555
           LDL LFSYDDKWVSVMERPK  G++PIRFYARDSGLLKF+I AG+LG+ +  + RRLVAF
Sbjct: 179 LDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAF 238

Query: 556 TFHPTDPFAISVQRTNSEYIVNFHIRN 582
           TFHP +PFAISVQRTN+EY+VNFH+R+
Sbjct: 239 TFHPFEPFAISVQRTNAEYVVNFHMRH 265


>BX649632-1|CAI18774.1|  334|Homo sapiens WD repeat domain 5
           protein.
          Length = 334

 Score = 34.7 bits (76), Expect = 0.92
 Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 1/37 (2%)

Query: 75  TIVNVEKPPCFLRKFSPDGKHFIAFSADQTSLEIYEY 111
           T+++ + PP    KFSP+GK+ +A + D T L++++Y
Sbjct: 208 TLIDDDNPPVSFVKFSPNGKYILAATLDNT-LKLWDY 243


>BC001635-1|AAH01635.1|  334|Homo sapiens WD repeat domain 5
           protein.
          Length = 334

 Score = 34.7 bits (76), Expect = 0.92
 Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 1/37 (2%)

Query: 75  TIVNVEKPPCFLRKFSPDGKHFIAFSADQTSLEIYEY 111
           T+++ + PP    KFSP+GK+ +A + D T L++++Y
Sbjct: 208 TLIDDDNPPVSFVKFSPNGKYILAATLDNT-LKLWDY 243


>AK000552-1|BAA91248.1|  334|Homo sapiens protein ( Homo sapiens
           cDNA FLJ20545 fis, clone KAT11476. ).
          Length = 334

 Score = 34.7 bits (76), Expect = 0.92
 Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 1/37 (2%)

Query: 75  TIVNVEKPPCFLRKFSPDGKHFIAFSADQTSLEIYEY 111
           T+++ + PP    KFSP+GK+ +A + D T L++++Y
Sbjct: 208 TLIDDDNPPVSFVKFSPNGKYILAATLDNT-LKLWDY 243


>AJ011376-1|CAB66159.1|  362|Homo sapiens hypothetical protein
           protein.
          Length = 362

 Score = 34.7 bits (76), Expect = 0.92
 Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 1/37 (2%)

Query: 75  TIVNVEKPPCFLRKFSPDGKHFIAFSADQTSLEIYEY 111
           T+++ + PP    KFSP+GK+ +A + D T L++++Y
Sbjct: 236 TLIDDDNPPVSFVKFSPNGKYILAATLDNT-LKLWDY 271


>CR457279-1|CAG33560.1|  330|Homo sapiens WDR5B protein.
          Length = 330

 Score = 33.5 bits (73), Expect = 2.1
 Identities = 14/37 (37%), Positives = 25/37 (67%), Gaps = 1/37 (2%)

Query: 75  TIVNVEKPPCFLRKFSPDGKHFIAFSADQTSLEIYEY 111
           T+V+ + PP    KFSP+GK+ +  + D T L++++Y
Sbjct: 204 TLVDDDNPPVSFVKFSPNGKYILTATLDNT-LKLWDY 239


>BC043494-1|AAH43494.1|  330|Homo sapiens WD repeat domain 5B
           protein.
          Length = 330

 Score = 33.5 bits (73), Expect = 2.1
 Identities = 14/37 (37%), Positives = 25/37 (67%), Gaps = 1/37 (2%)

Query: 75  TIVNVEKPPCFLRKFSPDGKHFIAFSADQTSLEIYEY 111
           T+V+ + PP    KFSP+GK+ +  + D T L++++Y
Sbjct: 204 TLVDDDNPPVSFVKFSPNGKYILTATLDNT-LKLWDY 239


>AK002149-1|BAA92110.1|  330|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11287 fis, clone PLACE1009596, weakly similar to
           VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
          Length = 330

 Score = 33.5 bits (73), Expect = 2.1
 Identities = 14/37 (37%), Positives = 25/37 (67%), Gaps = 1/37 (2%)

Query: 75  TIVNVEKPPCFLRKFSPDGKHFIAFSADQTSLEIYEY 111
           T+V+ + PP    KFSP+GK+ +  + D T L++++Y
Sbjct: 204 TLVDDDNPPVSFVKFSPNGKYILTATLDNT-LKLWDY 239


>AF082196-1|AAC36104.1|  119|Homo sapiens
           anti-pneumococcal/anti-dsDNA Ig H-chain Fab fragment
           protein.
          Length = 119

 Score = 31.9 bits (69), Expect = 6.5
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 433 RNARL-CADSQFTCSPSNNLYARLTQQRFKQTIVRAIYGGRTEA-TKRILAQLPISAQSY 490
           R+ RL CA S FT S S+  + R    +  + +    Y G T+     +  +  I   + 
Sbjct: 10  RSLRLSCAASGFTFSGSSMHWVRQAPGKRLEWVAVIWYDGNTKYYADSVKGRFTIFRDNS 69

Query: 491 SGSPYLDLGLFSYDDKWVSVMERPKAYGEYPIRFYARD 528
             + YL +     +D  V    R +  G+Y I +Y  D
Sbjct: 70  KNTLYLQMNRLRAEDTAVYYCARDRISGDYDIYYYGMD 107


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.323    0.139    0.417 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 87,158,400
Number of Sequences: 224733
Number of extensions: 3704786
Number of successful extensions: 7730
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 7697
Number of HSP's gapped (non-prelim): 19
length of query: 586
length of database: 73,234,838
effective HSP length: 94
effective length of query: 492
effective length of database: 52,109,936
effective search space: 25638088512
effective search space used: 25638088512
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 68 (31.5 bits)

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