Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001419-TA|BGIBMGA001419-PA|IPR001128|Cytochrome P450
(362 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 180 7e-45
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 180 7e-45
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 180 7e-45
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 180 7e-45
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 178 3e-44
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 178 3e-44
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 178 3e-44
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 178 3e-44
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 178 3e-44
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 178 3e-44
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 174 3e-43
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 174 3e-43
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 174 3e-43
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 173 6e-43
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 173 6e-43
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 173 6e-43
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 173 6e-43
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 173 6e-43
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 173 6e-43
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 173 6e-43
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 173 6e-43
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 173 6e-43
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 173 6e-43
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 173 6e-43
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 173 6e-43
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 173 8e-43
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 173 1e-42
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 172 1e-42
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 172 1e-42
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 172 1e-42
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 170 8e-42
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 170 8e-42
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 165 3e-40
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 136 9e-32
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 134 5e-31
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 134 5e-31
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 134 5e-31
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 134 5e-31
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 134 6e-31
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 134 6e-31
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 134 6e-31
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 132 2e-30
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 132 2e-30
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 132 2e-30
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 132 2e-30
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 132 2e-30
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 132 2e-30
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 132 2e-30
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 132 2e-30
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 132 2e-30
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 132 2e-30
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 132 2e-30
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 132 2e-30
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 132 2e-30
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 132 2e-30
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 132 2e-30
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 132 2e-30
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 132 2e-30
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 132 2e-30
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 132 2e-30
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 131 3e-30
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 131 3e-30
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 131 3e-30
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 131 3e-30
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 131 3e-30
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 131 3e-30
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 131 3e-30
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 131 3e-30
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 131 4e-30
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 129 2e-29
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 128 2e-29
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 128 2e-29
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 128 2e-29
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 128 3e-29
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 128 3e-29
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 128 4e-29
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 125 2e-28
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 125 2e-28
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 125 2e-28
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 125 2e-28
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 125 2e-28
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 125 2e-28
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 125 3e-28
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 122 2e-27
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 122 2e-27
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 122 2e-27
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 122 2e-27
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 116 2e-25
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 112 2e-24
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 111 3e-24
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 111 3e-24
AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, famil... 111 3e-24
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 111 3e-24
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 110 6e-24
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 110 6e-24
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 110 6e-24
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 110 6e-24
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 110 9e-24
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 109 2e-23
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 108 3e-23
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 108 3e-23
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 107 8e-23
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 106 1e-22
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 106 1e-22
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 106 1e-22
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 106 1e-22
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 100 2e-20
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 98 5e-20
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 98 5e-20
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 98 5e-20
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 98 5e-20
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 98 5e-20
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 98 5e-20
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 98 5e-20
AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 98 5e-20
AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 98 5e-20
AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 98 5e-20
AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 98 5e-20
AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 98 5e-20
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 98 5e-20
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 98 5e-20
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 97 1e-19
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 96 1e-19
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 96 1e-19
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 93 1e-18
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 93 1e-18
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 92 2e-18
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 92 2e-18
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 92 2e-18
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 92 2e-18
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 92 2e-18
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 92 2e-18
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 92 2e-18
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 92 2e-18
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 92 2e-18
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 92 2e-18
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 92 2e-18
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 90 1e-17
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 90 1e-17
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 89 2e-17
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 89 2e-17
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 89 2e-17
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 89 2e-17
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 89 2e-17
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 89 2e-17
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 89 2e-17
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 89 2e-17
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 89 2e-17
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 89 2e-17
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 89 2e-17
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 89 2e-17
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 88 5e-17
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 86 2e-16
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 86 2e-16
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 86 2e-16
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 86 2e-16
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 86 2e-16
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 86 2e-16
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 86 2e-16
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 86 2e-16
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 86 2e-16
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 86 2e-16
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 86 2e-16
AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 86 2e-16
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 86 2e-16
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 86 2e-16
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 84 6e-16
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 84 6e-16
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 84 6e-16
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 84 8e-16
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 84 8e-16
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 84 8e-16
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 84 8e-16
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 84 8e-16
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 84 8e-16
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 84 8e-16
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 84 8e-16
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 84 8e-16
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 83 1e-15
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 83 1e-15
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 83 1e-15
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 83 1e-15
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 83 1e-15
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 83 1e-15
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 83 1e-15
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 83 2e-15
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 82 3e-15
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 82 3e-15
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 82 3e-15
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 82 3e-15
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 82 3e-15
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 82 3e-15
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 82 3e-15
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 82 3e-15
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 82 3e-15
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 82 3e-15
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 82 3e-15
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 82 3e-15
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 82 3e-15
AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family... 82 3e-15
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 81 5e-15
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 81 5e-15
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 81 5e-15
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 81 5e-15
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 81 8e-15
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 80 1e-14
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 79 2e-14
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 79 2e-14
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 79 2e-14
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 79 2e-14
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 79 2e-14
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 79 3e-14
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 79 3e-14
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 79 3e-14
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 78 4e-14
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 78 4e-14
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 78 4e-14
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 78 4e-14
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 78 4e-14
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 78 4e-14
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 78 6e-14
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 78 6e-14
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 78 6e-14
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 78 6e-14
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 78 6e-14
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 77 7e-14
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 77 7e-14
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 77 7e-14
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 77 7e-14
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 77 7e-14
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 77 7e-14
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 77 7e-14
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 77 7e-14
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 77 7e-14
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 77 7e-14
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 77 7e-14
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 77 1e-13
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 77 1e-13
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 77 1e-13
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 77 1e-13
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 77 1e-13
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 77 1e-13
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 77 1e-13
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 76 2e-13
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 76 2e-13
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 76 2e-13
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 75 3e-13
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 5e-13
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 74 9e-13
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 73 1e-12
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 73 1e-12
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 73 1e-12
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 73 1e-12
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 73 1e-12
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 73 1e-12
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 73 1e-12
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 73 1e-12
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 73 1e-12
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 73 1e-12
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 73 2e-12
BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein. 73 2e-12
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 73 2e-12
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 73 2e-12
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 73 2e-12
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 73 2e-12
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 73 2e-12
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 73 2e-12
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 73 2e-12
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 73 2e-12
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 73 2e-12
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 73 2e-12
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 73 2e-12
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 73 2e-12
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 73 2e-12
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 73 2e-12
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 73 2e-12
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 73 2e-12
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 72 3e-12
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 72 3e-12
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 72 3e-12
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 72 3e-12
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 72 4e-12
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 72 4e-12
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 72 4e-12
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 72 4e-12
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 72 4e-12
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 72 4e-12
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 72 4e-12
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 72 4e-12
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 72 4e-12
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 72 4e-12
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 71 5e-12
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 71 6e-12
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 6e-12
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 6e-12
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 6e-12
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 6e-12
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 6e-12
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 6e-12
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 6e-12
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 6e-12
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 71 6e-12
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 71 6e-12
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 71 6e-12
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 71 6e-12
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 71 6e-12
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 71 6e-12
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 68 6e-11
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 68 6e-11
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 68 6e-11
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 68 6e-11
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 67 1e-10
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 66 2e-10
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 66 2e-10
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 66 2e-10
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 66 2e-10
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 66 2e-10
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 65 3e-10
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 65 3e-10
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 65 3e-10
BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 65 3e-10
BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 65 3e-10
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 65 3e-10
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 65 3e-10
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 65 3e-10
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 65 3e-10
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 65 3e-10
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 65 3e-10
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 65 3e-10
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 65 3e-10
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 65 3e-10
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 65 3e-10
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 65 3e-10
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 65 3e-10
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 65 4e-10
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 65 4e-10
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 65 4e-10
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 65 4e-10
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 65 4e-10
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 4e-10
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 65 4e-10
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 64 6e-10
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 63 1e-09
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 63 1e-09
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 63 1e-09
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 63 1e-09
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 63 1e-09
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 63 1e-09
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 63 1e-09
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 63 2e-09
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 62 2e-09
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 62 3e-09
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 62 4e-09
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 62 4e-09
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 62 4e-09
AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein. 62 4e-09
AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein. 62 4e-09
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 60 1e-08
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 60 2e-08
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 59 2e-08
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 59 2e-08
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 59 2e-08
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 59 2e-08
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 59 2e-08
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 59 2e-08
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 59 2e-08
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 59 2e-08
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 59 2e-08
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 59 2e-08
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 59 2e-08
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 59 2e-08
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 59 2e-08
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 59 2e-08
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 59 2e-08
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 59 2e-08
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 59 2e-08
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 58 4e-08
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 58 4e-08
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 58 4e-08
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 58 4e-08
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 58 4e-08
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 58 4e-08
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 58 4e-08
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 58 4e-08
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 58 4e-08
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 57 1e-07
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 56 1e-07
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 56 1e-07
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 54 6e-07
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 54 6e-07
AF176805-1|AAK11850.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 54 6e-07
AF127090-1|AAD20021.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 54 6e-07
AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1 pro... 54 6e-07
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 54 8e-07
AF029403-1|AAC95426.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 54 8e-07
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 54 1e-06
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 52 2e-06
X56088-1|CAA39568.1| 504|Homo sapiens cholesterol 7-alpha-hydr... 52 3e-06
M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha hydro... 52 3e-06
BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family... 52 3e-06
BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family... 52 3e-06
BC029155-1|AAH29155.1| 489|Homo sapiens Unknown (protein for IM... 50 1e-05
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 50 1e-05
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 49 2e-05
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 48 7e-05
AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1 pro... 46 2e-04
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 44 6e-04
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 44 6e-04
AL138805-2|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 44 6e-04
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 43 0.002
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 42 0.004
BC128535-1|AAI28536.1| 143|Homo sapiens LOC283480 protein protein. 42 0.004
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 40 0.010
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 39 0.024
BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family... 39 0.032
AF090320-1|AAD19877.1| 501|Homo sapiens sterol 12-alpha-hydroxy... 39 0.032
AF090318-1|AAC63037.1| 462|Homo sapiens sterol 12-alpha hydroxy... 39 0.032
BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family... 38 0.042
BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family... 38 0.055
BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family... 38 0.055
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 37 0.096
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 37 0.13
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 36 0.22
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 36 0.22
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 36 0.22
X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase ... 36 0.22
X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 36 0.22
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 33 1.6
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 33 1.6
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 33 1.6
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 33 1.6
AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein. 33 1.6
AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein. 33 1.6
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 33 1.6
BC056258-1|AAH56258.1| 359|Homo sapiens CYP19A1 protein protein. 32 2.7
BC020767-1|AAH20767.1| 360|Homo sapiens Unknown (protein for IM... 32 2.7
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 31 8.4
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 31 8.4
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 180 bits (438), Expect = 7e-45
Identities = 108/307 (35%), Positives = 168/307 (54%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
Y+M I + +FG+ ID+ +P ++ +++ R + F + + +L+ LN
Sbjct: 179 YSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQRNGKPTDRN--DFMDLILALRQLGDIQATKRNSEDKEYS 149
T+FP V F VK I E R K T ++ DF+ L++ +NS+D E
Sbjct: 239 TVFPRKVISFLTKSVKQIKEGRL-KETQKHRVDFLQLMI----------DSQNSKDSETH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q KV EID L +K T
Sbjct: 288 KALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + L Y + NETLR++ + L+R K D +I + I KG V+ +HHD
Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYVLHHD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ +V++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 180 bits (438), Expect = 7e-45
Identities = 108/307 (35%), Positives = 168/307 (54%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
Y+M I + +FG+ ID+ +P ++ +++ R + F + + +L+ LN
Sbjct: 179 YSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQRNGKPTDRN--DFMDLILALRQLGDIQATKRNSEDKEYS 149
T+FP V F VK I E R K T ++ DF+ L++ +NS+D E
Sbjct: 239 TVFPRKVISFLTKSVKQIKEGRL-KETQKHRVDFLQLMI----------DSQNSKDSETH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q KV EID L +K T
Sbjct: 288 KALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + L Y + NETLR++ + L+R K D +I + I KG V+ +HHD
Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYVLHHD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ +V++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 180 bits (438), Expect = 7e-45
Identities = 108/307 (35%), Positives = 168/307 (54%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
Y+M I + +FG+ ID+ +P ++ +++ R + F + + +L+ LN
Sbjct: 179 YSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQRNGKPTDRN--DFMDLILALRQLGDIQATKRNSEDKEYS 149
T+FP V F VK I E R K T ++ DF+ L++ +NS+D E
Sbjct: 239 TVFPRKVISFLTKSVKQIKEGRL-KETQKHRVDFLQLMI----------DSQNSKDSETH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q KV EID L +K T
Sbjct: 288 KALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + L Y + NETLR++ + L+R K D +I + I KG V+ +HHD
Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYVLHHD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ +V++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 180 bits (438), Expect = 7e-45
Identities = 108/307 (35%), Positives = 168/307 (54%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
Y+M I + +FG+ ID+ +P ++ +++ R + F + + +L+ LN
Sbjct: 179 YSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQRNGKPTDRN--DFMDLILALRQLGDIQATKRNSEDKEYS 149
T+FP V F VK I E R K T ++ DF+ L++ +NS+D E
Sbjct: 239 TVFPRKVISFLTKSVKQIKEGRL-KETQKHRVDFLQLMI----------DSQNSKDSETH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q KV EID L +K T
Sbjct: 288 KALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + L Y + NETLR++ + L+R K D +I + I KG V+ +HHD
Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYVLHHD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ +V++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 178 bits (433), Expect = 3e-44
Identities = 108/313 (34%), Positives = 165/313 (52%), Gaps = 17/313 (5%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
YTM I FG+++D+ +P LK ++++ +L F + + V + LN
Sbjct: 179 YTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
LFP V+ F K+ ++ + E R K R DF +Q+ D Q +K K
Sbjct: 239 GLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFF------QQMIDSQNSKETKSHKA--- 289
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID L +K VTY
Sbjct: 290 -LSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTY 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ L + Y + NETLR++ +V + R K D +I + I KG V+ +HHD
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVMVPIYALHHDP 405
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
KY+ P KF PERFS N + +IPFG GPRNCIGMRFA ++ +++ F F
Sbjct: 406 KYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465
Query: 331 ELAKNTPRNLDID 343
+ K T L +D
Sbjct: 466 KPCKETQIPLKLD 478
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 178 bits (433), Expect = 3e-44
Identities = 108/313 (34%), Positives = 165/313 (52%), Gaps = 17/313 (5%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
YTM I FG+++D+ +P LK ++++ +L F + + V + LN
Sbjct: 179 YTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
LFP V+ F K+ ++ + E R K R DF +Q+ D Q +K K
Sbjct: 239 GLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFF------QQMIDSQNSKETKSHKA--- 289
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID L +K VTY
Sbjct: 290 -LSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLA-NKAPVTY 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ L + Y + NETLR++ +V + R K D +I + I KG V+ +HHD
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVMVPIYALHHDP 405
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
KY+ P KF PERFS N + +IPFG GPRNCIGMRFA ++ +++ F F
Sbjct: 406 KYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465
Query: 331 ELAKNTPRNLDID 343
+ K T L +D
Sbjct: 466 KPCKETQIPLKLD 478
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 178 bits (433), Expect = 3e-44
Identities = 108/313 (34%), Positives = 165/313 (52%), Gaps = 17/313 (5%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
YTM I FG+++D+ +P LK ++++ +L F + + V + LN
Sbjct: 179 YTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
LFP V+ F K+ ++ + E R K R DF +Q+ D Q +K K
Sbjct: 239 GLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFF------QQMIDSQNSKETKSHKA--- 289
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID L +K VTY
Sbjct: 290 -LSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTY 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ L + Y + NETLR++ +V + R K D +I + I KG V+ +HHD
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVMVPIYALHHDP 405
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
KY+ P KF PERFS N + +IPFG GPRNCIGMRFA ++ +++ F F
Sbjct: 406 KYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465
Query: 331 ELAKNTPRNLDID 343
+ K T L +D
Sbjct: 466 KPCKETQIPLKLD 478
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 178 bits (433), Expect = 3e-44
Identities = 108/313 (34%), Positives = 165/313 (52%), Gaps = 17/313 (5%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
YTM I FG+++D+ +P LK ++++ +L F + + V + LN
Sbjct: 179 YTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
LFP V+ F K+ ++ + E R K R DF +Q+ D Q +K K
Sbjct: 239 GLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFF------QQMIDSQNSKETKSHKA--- 289
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID L +K VTY
Sbjct: 290 -LSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTY 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ L + Y + NETLR++ +V + R K D +I + I KG V+ +HHD
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVMVPIYALHHDP 405
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
KY+ P KF PERFS N + +IPFG GPRNCIGMRFA ++ +++ F F
Sbjct: 406 KYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465
Query: 331 ELAKNTPRNLDID 343
+ K T L +D
Sbjct: 466 KPCKETQIPLKLD 478
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 178 bits (433), Expect = 3e-44
Identities = 108/313 (34%), Positives = 165/313 (52%), Gaps = 17/313 (5%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
YTM I FG+++D+ +P LK ++++ +L F + + V + LN
Sbjct: 179 YTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
LFP V+ F K+ ++ + E R K R DF +Q+ D Q +K K
Sbjct: 239 GLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFF------QQMIDSQNSKETKSHKA--- 289
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID L +K VTY
Sbjct: 290 -LSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTY 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ L + Y + NETLR++ +V + R K D +I + I KG V+ +HHD
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVMVPIYALHHDP 405
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
KY+ P KF PERFS N + +IPFG GPRNCIGMRFA ++ +++ F F
Sbjct: 406 KYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465
Query: 331 ELAKNTPRNLDID 343
+ K T L +D
Sbjct: 466 KPCKETQIPLKLD 478
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 178 bits (433), Expect = 3e-44
Identities = 108/313 (34%), Positives = 165/313 (52%), Gaps = 17/313 (5%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
YTM I FG+++D+ +P LK ++++ +L F + + V + LN
Sbjct: 179 YTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
LFP V+ F K+ ++ + E R K R DF +Q+ D Q +K K
Sbjct: 239 GLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFF------QQMIDSQNSKETKSHKA--- 289
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID L +K VTY
Sbjct: 290 -LSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTY 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ L + Y + NETLR++ +V + R K D +I + I KG V+ +HHD
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVMVPIYALHHDP 405
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
KY+ P KF PERFS N + +IPFG GPRNCIGMRFA ++ +++ F F
Sbjct: 406 KYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465
Query: 331 ELAKNTPRNLDID 343
+ K T L +D
Sbjct: 466 KPCKETQIPLKLD 478
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 174 bits (424), Expect = 3e-43
Identities = 102/307 (33%), Positives = 169/307 (55%), Gaps = 18/307 (5%)
Query: 35 YTMATIAACAFGLDIDTTDPNKDQL-KTLEEIDRLSLTANFAFELDMMYP---GVLKKLN 90
Y+M I + +FG+++D+ + +D L + +++ R F + + +P +L+ LN
Sbjct: 179 YSMDVITSSSFGVNVDSLNNPQDPLVENTKKLLRFDFLDPFFLSITV-FPFLIPILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ + +NS++ E
Sbjct: 238 ICVFPREVTNFLRKAVKRMKESRLEDTQKHRVDFLQLMID---------SHKNSKETESH 288
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 289 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 347
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 348 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGWVVMIPSYALHRD 405
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 406 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 465
Query: 330 FELAKNT 336
F+ K T
Sbjct: 466 FKPCKET 472
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 174 bits (424), Expect = 3e-43
Identities = 107/310 (34%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYP---GVLK 87
Y+M I + +FG++ID+ DP + K L D L F L +++P +L+
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLD-----PFFLSIIFPFLIPILE 233
Query: 88 KLNSTLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDK 146
LN +FP V+ F + VK + E R R DF+ L++ +NS++
Sbjct: 234 VLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKET 283
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K
Sbjct: 284 ESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKA 342
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
TY+ + + Y + NETLR++ I L+R K D +I + I KG V+ +
Sbjct: 343 PPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGWVVMIPSYAL 400
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H D KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++
Sbjct: 401 HRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQ 460
Query: 327 KFRFELAKNT 336
F F+ K T
Sbjct: 461 NFSFKPCKET 470
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 174 bits (424), Expect = 3e-43
Identities = 102/307 (33%), Positives = 169/307 (55%), Gaps = 18/307 (5%)
Query: 35 YTMATIAACAFGLDIDTTDPNKDQL-KTLEEIDRLSLTANFAFELDMMYP---GVLKKLN 90
Y+M I + +FG+++D+ + +D L + +++ R F + + +P +L+ LN
Sbjct: 179 YSMDVITSSSFGVNVDSLNNPQDPLVENTKKLLRFDFLDPFFLSITV-FPFLIPILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ + +NS++ E
Sbjct: 238 ICVFPREVTNFLRKAVKRMKESRLEDTQKHRVDFLQLMID---------SHKNSKETESH 288
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 289 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 347
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 348 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGWVVMIPSYALHRD 405
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 406 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 465
Query: 330 FELAKNT 336
F+ K T
Sbjct: 466 FKPCKET 472
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 173 bits (422), Expect = 6e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 173 bits (422), Expect = 6e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 173 bits (422), Expect = 6e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 173 bits (422), Expect = 6e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 173 bits (422), Expect = 6e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 173 bits (422), Expect = 6e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 29 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 87
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 88 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 137
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 138 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 196
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 197 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 254
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 255 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 314
Query: 330 FELAKNT 336
F+ K T
Sbjct: 315 FKPCKET 321
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 173 bits (422), Expect = 6e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 106 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 164
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 165 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 214
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 215 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 273
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 274 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 331
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 332 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 391
Query: 330 FELAKNT 336
F+ K T
Sbjct: 392 FKPCKET 398
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 173 bits (422), Expect = 6e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 173 bits (422), Expect = 6e-43
Identities = 108/314 (34%), Positives = 165/314 (52%), Gaps = 18/314 (5%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
YTM I FG+++D+ +P LK ++++ +L F + + V + LN
Sbjct: 179 YTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
LFP V+ F K+ ++ + E R K R DF +Q+ D Q +K K
Sbjct: 239 GLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFF------QQMIDSQNSKETKSHKA--- 289
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID L +K VTY
Sbjct: 290 -LSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTY 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ L + Y + NETLR++ +V + R K D +I + I KG V+ +HHD
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVMVPIYALHHDP 405
Query: 271 KYYPNPSKFDPE-RFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PE RFS N + +IPFG GPRNCIGMRFA ++ +++ F
Sbjct: 406 KYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFS 465
Query: 330 FELAKNTPRNLDID 343
F+ K T L +D
Sbjct: 466 FKPCKETQIPLKLD 479
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 173 bits (422), Expect = 6e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 173 bits (422), Expect = 6e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 173 bits (422), Expect = 6e-43
Identities = 108/314 (34%), Positives = 165/314 (52%), Gaps = 18/314 (5%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
YTM I FG+++D+ +P LK ++++ +L F + + V + LN
Sbjct: 179 YTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
LFP V+ F K+ ++ + E R K R DF +Q+ D Q +K K
Sbjct: 239 GLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFF------QQMIDSQNSKETKSHKA--- 289
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID L +K VTY
Sbjct: 290 -LSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTY 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ L + Y + NETLR++ +V + R K D +I + I KG V+ +HHD
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVMVPIYALHHDP 405
Query: 271 KYYPNPSKFDPE-RFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PE RFS N + +IPFG GPRNCIGMRFA ++ +++ F
Sbjct: 406 KYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFS 465
Query: 330 FELAKNTPRNLDID 343
F+ K T L +D
Sbjct: 466 FKPCKETQIPLKLD 479
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 173 bits (421), Expect = 8e-43
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGWVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 173 bits (420), Expect = 1e-42
Identities = 105/307 (34%), Positives = 163/307 (53%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGWVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 172 bits (419), Expect = 1e-42
Identities = 103/314 (32%), Positives = 168/314 (53%), Gaps = 20/314 (6%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMMYP---GVLKKLN 90
Y+M I +FG++ID+ +P +++ ++ + + +++P V + LN
Sbjct: 179 YSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSI-ILFPFLTPVFEALN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+LFP F V + + R N K R DF+ L++ +NS++ E
Sbjct: 238 VSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F LY+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVL-PNKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ + L+R K D +I + I KG+ V+ +HHD
Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYALHHD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P +F PERFS S P + PFGTGPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEEFRPERFSKKKDSI-DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFS 463
Query: 330 FELAKNTPRNLDID 343
F+ K T L +D
Sbjct: 464 FKPCKETQIPLKLD 477
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 172 bits (419), Expect = 1e-42
Identities = 103/314 (32%), Positives = 168/314 (53%), Gaps = 20/314 (6%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMMYP---GVLKKLN 90
Y+M I +FG++ID+ +P +++ ++ + + +++P V + LN
Sbjct: 179 YSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSI-ILFPFLTPVFEALN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+LFP F V + + R N K R DF+ L++ +NS++ E
Sbjct: 238 VSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F LY+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVL-PNKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ + L+R K D +I + I KG+ V+ +HHD
Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYALHHD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P +F PERFS S P + PFGTGPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEEFRPERFSKKKDSI-DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFS 463
Query: 330 FELAKNTPRNLDID 343
F+ K T L +D
Sbjct: 464 FKPCKETQIPLKLD 477
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 172 bits (419), Expect = 1e-42
Identities = 103/314 (32%), Positives = 168/314 (53%), Gaps = 20/314 (6%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMMYP---GVLKKLN 90
Y+M I +FG++ID+ +P +++ ++ + + +++P V + LN
Sbjct: 179 YSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSI-ILFPFLTPVFEALN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+LFP F V + + R N K R DF+ L++ +NS++ E
Sbjct: 238 VSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F LY+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVL-PNKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ + L+R K D +I + I KG+ V+ +HHD
Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYALHHD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P +F PERFS S P + PFGTGPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEEFRPERFSKKKDSI-DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFS 463
Query: 330 FELAKNTPRNLDID 343
F+ K T L +D
Sbjct: 464 FKPCKETQIPLKLD 477
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 170 bits (413), Expect = 8e-42
Identities = 102/314 (32%), Positives = 167/314 (53%), Gaps = 20/314 (6%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMMYP---GVLKKLN 90
Y+M I +FG++ID+ +P +++ ++ + + +++P V + LN
Sbjct: 179 YSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSI-ILFPFLTPVFEALN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+LFP F V + + R N K R DF+ L++ +NS++ E
Sbjct: 238 VSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AGYET+++ ++F LY+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVL-PNKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ + L+R D +I + I KG+ V+ +HHD
Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCMKDVEI--NGVFIPKGSMVVIPTYALHHD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P +F PERFS S P + PFGTGPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEEFRPERFSKKKDSI-DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFS 463
Query: 330 FELAKNTPRNLDID 343
F+ K T L +D
Sbjct: 464 FKPCKETQIPLKLD 477
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 170 bits (413), Expect = 8e-42
Identities = 104/307 (33%), Positives = 162/307 (52%), Gaps = 19/307 (6%)
Query: 35 YTMATIAACAFGLDIDTT----DPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVLKKLN 90
Y+M I + +FG++ID+ DP + K L D L + P +L+ LN
Sbjct: 179 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIP-ILEVLN 237
Query: 91 STLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYS 149
+FP V+ F + VK + E R R DF+ L++ +NS++ E
Sbjct: 238 ICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMI----------DSQNSKETESH 287
Query: 150 IELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVT 209
L+D + AQ+ +F AG ET+++ ++F++Y+LA +PD+Q K+ EID L +K T
Sbjct: 288 KALSDLELVAQSIIFIFAGCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPT 346
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
Y+ + + Y + NETLR++ I L+R K D +I + I KG V+ +H D
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI--NGMFIPKGVVVMIPSYALHRD 404
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
KY+ P KF PERFS N P + PFG+GPRNCIGMRFA + ++ ++++ F
Sbjct: 405 PKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
Query: 330 FELAKNT 336
F+ K T
Sbjct: 465 FKPCKET 471
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 165 bits (400), Expect = 3e-40
Identities = 96/260 (36%), Positives = 141/260 (54%), Gaps = 14/260 (5%)
Query: 85 VLKKLNSTLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNS 143
V + LN LFP V+ F K+ ++ + E R K R DF +Q+ D Q +K
Sbjct: 122 VFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFF------QQMIDSQNSKETK 175
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
K L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID L
Sbjct: 176 SHKA----LSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP- 230
Query: 204 SKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSP 263
+K VTY+ L + Y + NETLR++ +V + R K D +I + I KG V+
Sbjct: 231 NKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVMVPI 288
Query: 264 LGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVK 323
+HHD KY+ P KF PERFS N + +IPFG GPRNCIGMRFA ++ +++
Sbjct: 289 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 348
Query: 324 MFSKFRFELAKNTPRNLDID 343
F F+ K T L +D
Sbjct: 349 ALQNFSFKPCKETQIPLKLD 368
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 136 bits (330), Expect = 9e-32
Identities = 88/315 (27%), Positives = 146/315 (46%), Gaps = 8/315 (2%)
Query: 27 DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEIDRLSLTANFAFELDMMYPGVL 86
D+ + T+ ++ C F D + + + + + E+ L + N F + L
Sbjct: 190 DVFEHISLMTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFFRYKDFLYFL 249
Query: 87 KKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDR--NDFMDLILALRQLGDIQATKRNSE 144
R D +I++R T + +DF+ + L I SE
Sbjct: 250 TPCGRRFHRA--CRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVLLL-SE 306
Query: 145 DKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKES 204
DK EL+DE I A+A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+
Sbjct: 307 DKNGK-ELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDR 365
Query: 205 KG-EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSP 263
+ E+ ++ L L + E+LR++ + R D +PD+ VI KG +
Sbjct: 366 EPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSR-VIPKGNVCNINI 424
Query: 264 LGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVK 323
IHH+ +P+P +DP RF P N R P A IPF GPRNCIG +FA + +V +
Sbjct: 425 FAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLAL 484
Query: 324 MFSKFRFELAKNTPR 338
+FR PR
Sbjct: 485 TLLRFRILPDHREPR 499
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 134 bits (324), Expect = 5e-31
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 2/180 (1%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+ E I + F G++T+A + + LY L NP++Q KV E+D +S T E
Sbjct: 314 LSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVE 373
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L+ L Y E ETLR++ V R+ D ++ ++ KGT + P +H D +
Sbjct: 374 DLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVL--KGTEAVIIPYALHRDPR 431
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
Y+PNP +F PERF P N RHP A++PF GPRNCIG +FA ++ + + + F E
Sbjct: 432 YFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIE 491
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 134 bits (324), Expect = 5e-31
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 2/180 (1%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+ E I + F G++T+A + + LY L NP++Q KV E+D +S T E
Sbjct: 314 LSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVE 373
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L+ L Y E ETLR++ V R+ D ++ ++ KGT + P +H D +
Sbjct: 374 DLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVL--KGTEAVIIPYALHRDPR 431
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
Y+PNP +F PERF P N RHP A++PF GPRNCIG +FA ++ + + + F E
Sbjct: 432 YFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIE 491
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 134 bits (324), Expect = 5e-31
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 2/180 (1%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+ E I + F G++T+A + + LY L NP++Q KV E+D +S T E
Sbjct: 292 LSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVE 351
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L+ L Y E ETLR++ V R+ D ++ ++ KGT + P +H D +
Sbjct: 352 DLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVL--KGTEAVIIPYALHRDPR 409
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
Y+PNP +F PERF P N RHP A++PF GPRNCIG +FA ++ + + + F E
Sbjct: 410 YFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIE 469
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 134 bits (324), Expect = 5e-31
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 2/180 (1%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+ E I + F G++T+A + + LY L NP++Q KV E+D +S T E
Sbjct: 314 LSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVE 373
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L+ L Y E ETLR++ V R+ D ++ ++ KGT + P +H D +
Sbjct: 374 DLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVL--KGTEAVIIPYALHRDPR 431
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
Y+PNP +F PERF P N RHP A++PF GPRNCIG +FA ++ + + + F E
Sbjct: 432 YFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIE 491
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 134 bits (323), Expect = 6e-31
Identities = 96/369 (26%), Positives = 166/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ AFG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 134 bits (323), Expect = 6e-31
Identities = 96/369 (26%), Positives = 166/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ AFG +D+ DP
Sbjct: 84 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFV 143
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 144 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 201
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 202 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 261
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 262 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 321
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 322 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 379
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 380 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 439
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 440 ETQVPLQLE 448
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 134 bits (323), Expect = 6e-31
Identities = 96/369 (26%), Positives = 166/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ AFG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (319), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPENFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 132 bits (318), Expect = 2e-30
Identities = 80/239 (33%), Positives = 125/239 (52%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R P+ +DF+ + L I + + E +L+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD--EDGKKLSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L +L +
Sbjct: 322 ADTFMFEGHDTTASVLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R+ D +PD VI KG L S G HH+ +P+P +
Sbjct: 382 TMCMKESLRVHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF P NI R P A IPF GPRNCIG FA + +V + +FR PR
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPR 499
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ AFG +D+ DP
Sbjct: 151 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFV 210
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 211 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 268
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 269 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 328
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 329 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 388
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 389 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 446
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+ ++ ++ ++ + KFRF+
Sbjct: 447 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHVLHKFRFQACP 506
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 507 ETQVPLQLE 515
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 132 bits (318), Expect = 2e-30
Identities = 91/316 (28%), Positives = 147/316 (46%), Gaps = 10/316 (3%)
Query: 27 DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEIDRL--SLTANFAFELDMMYPG 84
D+ + T+ ++ C F D + + + T+ E+ L + + +D +Y
Sbjct: 190 DMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFLY-- 247
Query: 85 VLKKLNSTLFPGFVSRFFKDVVKTII-EQRNGKPTDRNDFMDLILALRQLGDIQATKRNS 143
+ F R D +I E+R PT D A + D S
Sbjct: 248 -YLSHDGRRFHR-ACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLS 305
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
+D++ L+DE I A+A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+
Sbjct: 306 KDEDGKA-LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKD 364
Query: 204 -SKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFS 262
E+ ++ L L + E+LR++ + R D +PD VI KG T L
Sbjct: 365 RDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLID 423
Query: 263 PLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMV 322
+G+HH+ +P+P +DP RF P N R P A IPF GPRNCIG FA + +V +
Sbjct: 424 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 323 KMFSKFRFELAKNTPR 338
M FRF PR
Sbjct: 484 LMLLHFRFLPDHTEPR 499
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 132 bits (318), Expect = 2e-30
Identities = 91/316 (28%), Positives = 147/316 (46%), Gaps = 10/316 (3%)
Query: 27 DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEIDRL--SLTANFAFELDMMYPG 84
D+ + T+ ++ C F D + + + T+ E+ L + + +D +Y
Sbjct: 190 DMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFLY-- 247
Query: 85 VLKKLNSTLFPGFVSRFFKDVVKTII-EQRNGKPTDRNDFMDLILALRQLGDIQATKRNS 143
+ F R D +I E+R PT D A + D S
Sbjct: 248 -YLSHDGRRFHR-ACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLS 305
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
+D++ L+DE I A+A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+
Sbjct: 306 KDEDGKA-LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKD 364
Query: 204 -SKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFS 262
E+ ++ L L + E+LR++ + R D +PD VI KG T L
Sbjct: 365 RDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLID 423
Query: 263 PLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMV 322
+G+HH+ +P+P +DP RF P N R P A IPF GPRNCIG FA + +V +
Sbjct: 424 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 323 KMFSKFRFELAKNTPR 338
M FRF PR
Sbjct: 484 LMLLHFRFLPDHTEPR 499
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 132 bits (318), Expect = 2e-30
Identities = 91/316 (28%), Positives = 147/316 (46%), Gaps = 10/316 (3%)
Query: 27 DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEIDRL--SLTANFAFELDMMYPG 84
D+ + T+ ++ C F D + + + T+ E+ L + + +D +Y
Sbjct: 190 DMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFLY-- 247
Query: 85 VLKKLNSTLFPGFVSRFFKDVVKTII-EQRNGKPTDRNDFMDLILALRQLGDIQATKRNS 143
+ F R D +I E+R PT D A + D S
Sbjct: 248 -YLSHDGRRFHR-ACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLS 305
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
+D++ L+DE I A+A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+
Sbjct: 306 KDEDGKA-LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKD 364
Query: 204 -SKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFS 262
E+ ++ L L + E+LR++ + R D +PD VI KG T L
Sbjct: 365 RDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLID 423
Query: 263 PLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMV 322
+G+HH+ +P+P +DP RF P N R P A IPF GPRNCIG FA + +V +
Sbjct: 424 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 323 KMFSKFRFELAKNTPR 338
M FRF PR
Sbjct: 484 LMLLHFRFLPDHTEPR 499
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPKTFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAEDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYVLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPSKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 132 bits (318), Expect = 2e-30
Identities = 95/369 (25%), Positives = 165/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 132 bits (318), Expect = 2e-30
Identities = 91/316 (28%), Positives = 147/316 (46%), Gaps = 10/316 (3%)
Query: 27 DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEIDRL--SLTANFAFELDMMYPG 84
D+ + T+ ++ C F D + + + T+ E+ L + + +D +Y
Sbjct: 124 DMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFLY-- 181
Query: 85 VLKKLNSTLFPGFVSRFFKDVVKTII-EQRNGKPTDRNDFMDLILALRQLGDIQATKRNS 143
+ F R D +I E+R PT D A + D S
Sbjct: 182 -YLSHDGRRFHR-ACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLS 239
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
+D++ L+DE I A+A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+
Sbjct: 240 KDEDGKA-LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKD 298
Query: 204 -SKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFS 262
E+ ++ L L + E+LR++ + R D +PD VI KG T L
Sbjct: 299 RDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLID 357
Query: 263 PLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMV 322
+G+HH+ +P+P +DP RF P N R P A IPF GPRNCIG FA + +V +
Sbjct: 358 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 417
Query: 323 KMFSKFRFELAKNTPR 338
M FRF PR
Sbjct: 418 LMLLHFRFLPDHTEPR 433
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 132 bits (318), Expect = 2e-30
Identities = 91/316 (28%), Positives = 147/316 (46%), Gaps = 10/316 (3%)
Query: 27 DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEIDRL--SLTANFAFELDMMYPG 84
D+ + T+ ++ C F D + + + T+ E+ L + + +D +Y
Sbjct: 190 DMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFLY-- 247
Query: 85 VLKKLNSTLFPGFVSRFFKDVVKTII-EQRNGKPTDRNDFMDLILALRQLGDIQATKRNS 143
+ F R D +I E+R PT D A + D S
Sbjct: 248 -YLSHDGRRFHR-ACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLS 305
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
+D++ L+DE I A+A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+
Sbjct: 306 KDEDGKA-LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKD 364
Query: 204 -SKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFS 262
E+ ++ L L + E+LR++ + R D +PD VI KG T L
Sbjct: 365 RDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLID 423
Query: 263 PLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMV 322
+G+HH+ +P+P +DP RF P N R P A IPF GPRNCIG FA + +V +
Sbjct: 424 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 323 KMFSKFRFELAKNTPR 338
M FRF PR
Sbjct: 484 LMLLHFRFLPDHTEPR 499
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 132 bits (318), Expect = 2e-30
Identities = 91/316 (28%), Positives = 147/316 (46%), Gaps = 10/316 (3%)
Query: 27 DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEIDRL--SLTANFAFELDMMYPG 84
D+ + T+ ++ C F D + + + T+ E+ L + + +D +Y
Sbjct: 190 DMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFLY-- 247
Query: 85 VLKKLNSTLFPGFVSRFFKDVVKTII-EQRNGKPTDRNDFMDLILALRQLGDIQATKRNS 143
+ F R D +I E+R PT D A + D S
Sbjct: 248 -YLSHDGRRFHR-ACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLS 305
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
+D++ L+DE I A+A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+
Sbjct: 306 KDEDGKA-LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKD 364
Query: 204 -SKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFS 262
E+ ++ L L + E+LR++ + R D +PD VI KG T L
Sbjct: 365 RDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLID 423
Query: 263 PLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMV 322
+G+HH+ +P+P +DP RF P N R P A IPF GPRNCIG FA + +V +
Sbjct: 424 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 323 KMFSKFRFELAKNTPR 338
M FRF PR
Sbjct: 484 LMLLHFRFLPDHTEPR 499
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 131 bits (317), Expect = 3e-30
Identities = 80/239 (33%), Positives = 125/239 (52%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R P+ +DF+ + L I + + E +L+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD--EDGKKLSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L +L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R+ D +PD VI KG L S G HH+ +P+P +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF P NI R P A IPF GPRNCIG FA + +V + +FR PR
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPR 499
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 131 bits (317), Expect = 3e-30
Identities = 80/239 (33%), Positives = 125/239 (52%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R P+ +DF+ + L I + + E +L+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD--EDGKKLSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L +L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R+ D +PD VI KG L S G HH+ +P+P +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAMWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF P NI R P A IPF GPRNCIG FA + +V + +FR PR
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPR 499
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 131 bits (317), Expect = 3e-30
Identities = 80/239 (33%), Positives = 125/239 (52%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R P+ +DF+ + L I + + E +L+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD--EDGKKLSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L +L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R+ D +PD VI KG L S G HH+ +P+P +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF P NI R P A IPF GPRNCIG FA + +V + +FR PR
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPR 499
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 131 bits (317), Expect = 3e-30
Identities = 80/239 (33%), Positives = 125/239 (52%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R P+ +DF+ + L I + + E +L+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD--EDGKKLSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L +L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R+ D +PD VI KG L S G HH+ +P+P +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF P NI R P A IPF GPRNCIG FA + +V + +FR PR
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPR 499
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 131 bits (317), Expect = 3e-30
Identities = 80/239 (33%), Positives = 125/239 (52%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R P+ +DF+ + L I + + E +L+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD--EDGKKLSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L +L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R+ D +PD VI KG L S G HH+ +P+P +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF P NI R P A IPF GPRNCIG FA + +V + +FR PR
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPR 499
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 131 bits (317), Expect = 3e-30
Identities = 95/369 (25%), Positives = 164/369 (44%), Gaps = 30/369 (8%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACELLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRI--PAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
+P F+PERF+ P ++PFG GPR+C+G+R ++ ++ ++ + KFRF+
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507
Query: 335 NTPRNLDID 343
T L ++
Sbjct: 508 ETQVPLQLE 516
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 131 bits (317), Expect = 3e-30
Identities = 80/239 (33%), Positives = 125/239 (52%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R P+ +DF+ + L I + + E +L+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD--EDGKKLSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L +L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R+ D +PD VI KG L S G HH+ +P+P +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF P NI R P A IPF GPRNCIG FA + +V + +FR PR
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPR 499
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 131 bits (317), Expect = 3e-30
Identities = 80/239 (33%), Positives = 125/239 (52%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R P+ +DF+ + L I + + E +L+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD--EDGKKLSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L +L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R+ D +PD VI KG L S G HH+ +P+P +
Sbjct: 382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAMWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF P NI R P A IPF GPRNCIG FA + +V + +FR PR
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPR 499
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 131 bits (316), Expect = 4e-30
Identities = 84/253 (33%), Positives = 132/253 (52%), Gaps = 17/253 (6%)
Query: 35 YTMATIAACAFGLDIDT-TDPNKDQLKTLEEIDRLSLTANFAFELDMM--YPGVLKKLNS 91
YTM I FG+++D+ +P LK ++++ +L F + + V + LN
Sbjct: 179 YTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNI 238
Query: 92 TLFPGFVSRFFKDVVKTIIEQR-NGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
LFP V+ F K+ ++ + E R K R DF +Q+ D Q +K K
Sbjct: 239 GLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFF------QQMIDSQNSKETKSHKA--- 289
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID L +K VTY
Sbjct: 290 -LSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVL-PNKAPVTY 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ L + Y + NETLR++ +V + R K D +I + I KG V+ +HHD
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVMVPIYALHHDP 405
Query: 271 KYYPNPSKFDPER 283
KY+ P KF PER
Sbjct: 406 KYWTEPEKFCPER 418
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 129 bits (311), Expect = 2e-29
Identities = 80/239 (33%), Positives = 125/239 (52%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R PT +DF+ + L I + + E EL+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKD--EDGKELSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R D+ +PD VI KG L + +GIH++ +P+P +
Sbjct: 382 TMCIKESLRLHPPVPVISRCCTQDFVLPDGR-VIPKGIVCLINIIGIHYNPTVWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF+ NI R P A IPF GPRNCIG FA + +V + FR PR
Sbjct: 441 DPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPR 499
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 128 bits (310), Expect = 2e-29
Identities = 89/316 (28%), Positives = 146/316 (46%), Gaps = 10/316 (3%)
Query: 27 DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEIDRLSLTAN--FAFELDMMYPG 84
D+ + T+ ++ C F D + + + + E+ L + +D +Y
Sbjct: 190 DMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYL 249
Query: 85 VLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNS 143
V F DV++ E+R P+ +DF+ + L I +
Sbjct: 250 TPDGQRFRRACRLVHDFTDDVIQ---ERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
+ E +L+DE I A+A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+
Sbjct: 307 D--EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKD 364
Query: 204 SKG-EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFS 262
+ E+ ++ L L + E+LR++ V + R D +PD VI KG L S
Sbjct: 365 REPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGR-VIPKGIICLIS 423
Query: 263 PLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMV 322
G HH+ +P+P +DP RF P NI R P A IPF GPRNCIG FA + +V +
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
Query: 323 KMFSKFRFELAKNTPR 338
FR PR
Sbjct: 484 LTLLAFRVLPDHTEPR 499
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 128 bits (310), Expect = 2e-29
Identities = 89/316 (28%), Positives = 146/316 (46%), Gaps = 10/316 (3%)
Query: 27 DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEIDRLSLTAN--FAFELDMMYPG 84
D+ + T+ ++ C F D + + + + E+ L + +D +Y
Sbjct: 190 DMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYL 249
Query: 85 VLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNS 143
V F DV++ E+R P+ +DF+ + L I +
Sbjct: 250 TPDGQRFRRACRLVHDFTDDVIQ---ERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
+ E +L+DE I A+A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+
Sbjct: 307 D--EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKD 364
Query: 204 SKG-EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFS 262
+ E+ ++ L L + E+LR++ V + R D +PD VI KG L S
Sbjct: 365 REPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGR-VIPKGIICLIS 423
Query: 263 PLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMV 322
G HH+ +P+P +DP RF P NI R P A IPF GPRNCIG FA + +V +
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
Query: 323 KMFSKFRFELAKNTPR 338
FR PR
Sbjct: 484 LTLLAFRVLPDHTEPR 499
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 128 bits (310), Expect = 2e-29
Identities = 89/316 (28%), Positives = 146/316 (46%), Gaps = 10/316 (3%)
Query: 27 DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEIDRLSLTAN--FAFELDMMYPG 84
D+ + T+ ++ C F D + + + + E+ L + +D +Y
Sbjct: 190 DMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYL 249
Query: 85 VLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNS 143
V F DV++ E+R P+ +DF+ + L I +
Sbjct: 250 TPDGQRFRRACRLVHDFTDDVIQ---ERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
+ E +L+DE I A+A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+
Sbjct: 307 D--EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKD 364
Query: 204 SKG-EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFS 262
+ E+ ++ L L + E+LR++ V + R D +PD VI KG L S
Sbjct: 365 REPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGR-VIPKGIICLIS 423
Query: 263 PLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMV 322
G HH+ +P+P +DP RF P NI R P A IPF GPRNCIG FA + +V +
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
Query: 323 KMFSKFRFELAKNTPR 338
FR PR
Sbjct: 484 LTLLAFRVLPDHTEPR 499
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 128 bits (309), Expect = 3e-29
Identities = 80/239 (33%), Positives = 123/239 (51%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R P+ +DF+ + L I + + E +L+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD--EDGKKLSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R D +PD VI KG L S G HH+ +P+P +
Sbjct: 382 TMCIKESLRLHPPVPAVSRCCTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF P NI R P A IPF GPRNCIG FA + +V + +FR PR
Sbjct: 441 DPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPR 499
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 128 bits (309), Expect = 3e-29
Identities = 80/239 (33%), Positives = 123/239 (51%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R P+ +DF+ + L I + + E +L+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD--EDGKKLSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R D +PD VI KG L S G HH+ +P+P +
Sbjct: 382 TMCIKESLRLHPPVPAVSRCCTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF P NI R P A IPF GPRNCIG FA + +V + +FR PR
Sbjct: 441 DPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPR 499
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 128 bits (308), Expect = 4e-29
Identities = 80/239 (33%), Positives = 125/239 (52%), Gaps = 7/239 (2%)
Query: 102 FKDVVKTIIEQRNGKPTDR-NDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQ 160
F D V I E+R PT +DF+ + L I + + E EL+DE I A+
Sbjct: 266 FTDAV--IQERRRTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKD--EDGKELSDEDIRAE 321
Query: 161 AFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG-EVTYEMLQNLTYF 219
A F G++T+A+ ++++LY LA +P+ Q++ E+ + LK+ + E+ ++ L L +
Sbjct: 322 ADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFL 381
Query: 220 EKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKF 279
E+LR++ V + R D+ +PD VI KG L + +GIH++ +P+P +
Sbjct: 382 TMCIKESLRLHPPVPVISRCCTQDFVLPDGR-VIPKGIVCLINIIGIHYNPTVWPDPEVY 440
Query: 280 DPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
DP RF+ NI R P A IPF GPRNCIG FA + +V + FR PR
Sbjct: 441 DPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHIEPR 499
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 125 bits (302), Expect = 2e-28
Identities = 85/332 (25%), Positives = 156/332 (46%), Gaps = 12/332 (3%)
Query: 2 LHLMIERANKYIEHVEMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDID--TTDPNKDQ 58
+ +M ++ E +C Q +++ + ++ I CAF + + T +
Sbjct: 153 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPY 212
Query: 59 LKTLEEIDRLSLTANFAFELDMMYPGVLKKLNSTLFP-GFVSRFFKDVVKTIIEQRNGKP 117
K + E+ ++ ++ + + ++ KL+ + +SR TII++R K
Sbjct: 213 AKAIFELSKIIFHRLYSL---LYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERK-KS 268
Query: 118 TDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
D R+ D +++D+ S +D + ++ F +AG++T A +++
Sbjct: 269 LQAGVKQDNT-PKRKYQDFLDIVLSAKDESGS-SFSDIDVHSEVSTFLLAGHDTLAASIS 326
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LALNP+ Q++ E+ +G+ +T++ L ++Y ET R+ V +
Sbjct: 327 WILYCLALNPEHQERCREEV-RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSIS 385
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R+ PD + G TV+ S G+HH+ + NP FDP RFS N RHP A+
Sbjct: 386 RDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAY 444
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+PF G RNCIG FA I+ +V + + FR
Sbjct: 445 LPFSAGSRNCIGQEFAMIELKVTIALILLHFR 476
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 125 bits (302), Expect = 2e-28
Identities = 85/332 (25%), Positives = 156/332 (46%), Gaps = 12/332 (3%)
Query: 2 LHLMIERANKYIEHVEMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDID--TTDPNKDQ 58
+ +M ++ E +C Q +++ + ++ I CAF + + T +
Sbjct: 153 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPY 212
Query: 59 LKTLEEIDRLSLTANFAFELDMMYPGVLKKLNSTLFP-GFVSRFFKDVVKTIIEQRNGKP 117
K + E+ ++ ++ + + ++ KL+ + +SR TII++R K
Sbjct: 213 AKAIFELSKIIFHRLYSL---LYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERK-KS 268
Query: 118 TDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
D R+ D +++D+ S +D + ++ F +AG++T A +++
Sbjct: 269 LQAGVKQDNT-PKRKYQDFLDIVLSAKDESGS-SFSDIDVHSEVSTFLLAGHDTLAASIS 326
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LALNP+ Q++ E+ +G+ +T++ L ++Y ET R+ V +
Sbjct: 327 WILYCLALNPEHQERCREEV-RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSIS 385
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R+ PD + G TV+ S G+HH+ + NP FDP RFS N RHP A+
Sbjct: 386 RDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAY 444
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+PF G RNCIG FA I+ +V + + FR
Sbjct: 445 LPFSAGSRNCIGQEFAMIELKVTIALILLHFR 476
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 125 bits (302), Expect = 2e-28
Identities = 85/332 (25%), Positives = 156/332 (46%), Gaps = 12/332 (3%)
Query: 2 LHLMIERANKYIEHVEMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDID--TTDPNKDQ 58
+ +M ++ E +C Q +++ + ++ I CAF + + T +
Sbjct: 153 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPY 212
Query: 59 LKTLEEIDRLSLTANFAFELDMMYPGVLKKLNSTLFP-GFVSRFFKDVVKTIIEQRNGKP 117
K + E+ ++ ++ + + ++ KL+ + +SR TII++R K
Sbjct: 213 AKAIFELSKIIFHRLYSL---LYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERK-KS 268
Query: 118 TDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
D R+ D +++D+ S +D + ++ F +AG++T A +++
Sbjct: 269 LQAGVKQDNT-PKRKYQDFLDIVLSAKDESGS-SFSDIDVHSEVSTFLLAGHDTLAASIS 326
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LALNP+ Q++ E+ +G+ +T++ L ++Y ET R+ V +
Sbjct: 327 WILYCLALNPEHQERCREEV-RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSIS 385
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R+ PD + G TV+ S G+HH+ + NP FDP RFS N RHP A+
Sbjct: 386 RDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAY 444
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+PF G RNCIG FA I+ +V + + FR
Sbjct: 445 LPFSAGSRNCIGQEFAMIELKVTIALILLHFR 476
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 125 bits (302), Expect = 2e-28
Identities = 85/332 (25%), Positives = 156/332 (46%), Gaps = 12/332 (3%)
Query: 2 LHLMIERANKYIEHVEMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDID--TTDPNKDQ 58
+ +M ++ E +C Q +++ + ++ I CAF + + T +
Sbjct: 153 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPY 212
Query: 59 LKTLEEIDRLSLTANFAFELDMMYPGVLKKLNSTLFP-GFVSRFFKDVVKTIIEQRNGKP 117
K + E+ ++ ++ + + ++ KL+ + +SR TII++R K
Sbjct: 213 AKAIFELSKIIFHRLYSL---LYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERK-KS 268
Query: 118 TDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
D R+ D +++D+ S +D + ++ F +AG++T A +++
Sbjct: 269 LQAGVKQDNT-PKRKYQDFLDIVLSAKDESGS-SFSDIDVHSEVSTFLLAGHDTLAASIS 326
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LALNP+ Q++ E+ +G+ +T++ L ++Y ET R+ V +
Sbjct: 327 WILYCLALNPEHQERCREEV-RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSIS 385
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R+ PD + G TV+ S G+HH+ + NP FDP RFS N RHP A+
Sbjct: 386 RDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAY 444
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+PF G RNCIG FA I+ +V + + FR
Sbjct: 445 LPFSAGSRNCIGQEFAMIELKVTIALILLHFR 476
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 125 bits (302), Expect = 2e-28
Identities = 85/332 (25%), Positives = 156/332 (46%), Gaps = 12/332 (3%)
Query: 2 LHLMIERANKYIEHVEMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDID--TTDPNKDQ 58
+ +M ++ E +C Q +++ + ++ I CAF + + T +
Sbjct: 153 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPY 212
Query: 59 LKTLEEIDRLSLTANFAFELDMMYPGVLKKLNSTLFP-GFVSRFFKDVVKTIIEQRNGKP 117
K + E+ ++ ++ + + ++ KL+ + +SR TII++R K
Sbjct: 213 AKAIFELSKIIFHRLYSL---LYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERK-KS 268
Query: 118 TDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
D R+ D +++D+ S +D + ++ F +AG++T A +++
Sbjct: 269 LQAGVKQDNT-PKRKYQDFLDIVLSAKDESGS-SFSDIDVHSEVSTFLLAGHDTLAASIS 326
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LALNP+ Q++ E+ +G+ +T++ L ++Y ET R+ V +
Sbjct: 327 WILYCLALNPEHQERCREEV-RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSIS 385
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R+ PD + G TV+ S G+HH+ + NP FDP RFS N RHP A+
Sbjct: 386 RDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAY 444
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+PF G RNCIG FA I+ +V + + FR
Sbjct: 445 LPFSAGSRNCIGQEFAMIELKVTIALILLHFR 476
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 125 bits (302), Expect = 2e-28
Identities = 85/332 (25%), Positives = 156/332 (46%), Gaps = 12/332 (3%)
Query: 2 LHLMIERANKYIEHVEMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDID--TTDPNKDQ 58
+ +M ++ E +C Q +++ + ++ I CAF + + T +
Sbjct: 88 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPY 147
Query: 59 LKTLEEIDRLSLTANFAFELDMMYPGVLKKLNSTLFP-GFVSRFFKDVVKTIIEQRNGKP 117
K + E+ ++ ++ + + ++ KL+ + +SR TII++R K
Sbjct: 148 AKAIFELSKIIFHRLYSL---LYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERK-KS 203
Query: 118 TDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
D R+ D +++D+ S +D + ++ F +AG++T A +++
Sbjct: 204 LQAGVKQDNT-PKRKYQDFLDIVLSAKDESGS-SFSDIDVHSEVSTFLLAGHDTLAASIS 261
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LALNP+ Q++ E+ +G+ +T++ L ++Y ET R+ V +
Sbjct: 262 WILYCLALNPEHQERCREEV-RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSIS 320
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R+ PD + G TV+ S G+HH+ + NP FDP RFS N RHP A+
Sbjct: 321 RDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAY 379
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+PF G RNCIG FA I+ +V + + FR
Sbjct: 380 LPFSAGSRNCIGQEFAMIELKVTIALILLHFR 411
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 125 bits (301), Expect = 3e-28
Identities = 84/332 (25%), Positives = 156/332 (46%), Gaps = 12/332 (3%)
Query: 2 LHLMIERANKYIEHVEMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDID--TTDPNKDQ 58
+ +M ++ E +C Q +++ + ++ + CAF + + T +
Sbjct: 152 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIVMKCAFSKETNCQTNSTHDPY 211
Query: 59 LKTLEEIDRLSLTANFAFELDMMYPGVLKKLNSTLFP-GFVSRFFKDVVKTIIEQRNGKP 117
K + E+ ++ ++ + + ++ KL+ + +SR TII++R K
Sbjct: 212 AKAIFELSKIIFHRLYSL---LYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERK-KS 267
Query: 118 TDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
D R+ D +++D+ S +D + ++ F +AG++T A +++
Sbjct: 268 LQAGVKQDNT-PKRKYQDFLDIVLSAKDESGS-SFSDIDVHSEVSTFLLAGHDTLAASIS 325
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LALNP+ Q++ E+ +G+ +T++ L ++Y ET R+ V +
Sbjct: 326 WILYCLALNPEHQERCREEV-RGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSIS 384
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R+ PD + G TV+ S G+HH+ + NP FDP RFS N RHP A+
Sbjct: 385 RDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAY 443
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+PF G RNCIG FA I+ +V + + FR
Sbjct: 444 LPFSAGSRNCIGQEFAMIELKVTIALILLHFR 475
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 122 bits (294), Expect = 2e-27
Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 2/183 (1%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESK-GEVT 209
EL+DE I A+A F G++T+++ +++ML+ LA P+ Q+K EI + +K + E+
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
++ L L + E+LR Y V + R D K+PD I I KG L S G HH+
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRI-IPKGIICLVSIYGTHHN 437
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P+ ++P RF P N R P A++PF GPRNCIG FA + RV + +FR
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFR 497
Query: 330 FEL 332
+
Sbjct: 498 LSV 500
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 122 bits (294), Expect = 2e-27
Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 2/183 (1%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESK-GEVT 209
EL+DE I A+A F G++T+++ +++ML+ LA P+ Q+K EI + +K + E+
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
++ L L + E+LR Y V + R D K+PD I I KG L S G HH+
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRI-IPKGIICLVSIYGTHHN 437
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P+ ++P RF P N R P A++PF GPRNCIG FA + RV + +FR
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFR 497
Query: 330 FEL 332
+
Sbjct: 498 LSV 500
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 122 bits (294), Expect = 2e-27
Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 2/183 (1%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESK-GEVT 209
EL+DE I A+A F G++T+++ +++ML+ LA P+ Q+K EI + +K + E+
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
++ L L + E+LR Y V + R D K+PD I I KG L S G HH+
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRI-IPKGIICLVSIYGTHHN 437
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P+ ++P RF P N R P A++PF GPRNCIG FA + RV + +FR
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFR 497
Query: 330 FEL 332
+
Sbjct: 498 LSV 500
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 122 bits (294), Expect = 2e-27
Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 2/183 (1%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESK-GEVT 209
EL+DE I A+A F G++T+++ +++ML+ LA P+ Q+K EI + +K + E+
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
++ L L + E+LR Y V + R D K+PD I I KG L S G HH+
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRI-IPKGIICLVSIYGTHHN 437
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P+ ++P RF P N R P A++PF GPRNCIG FA + RV + +FR
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFR 497
Query: 330 FEL 332
+
Sbjct: 498 LSV 500
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 116 bits (278), Expect = 2e-25
Identities = 67/187 (35%), Positives = 99/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI GL +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEI-HGLLGDGASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP RF+P SA+H A +PF G RNCIG +FA Q +V + + RFE
Sbjct: 424 VWPNPEVFDPSRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNQLKV--ARALTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 112 bits (270), Expect = 2e-24
Identities = 66/187 (35%), Positives = 99/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP RF+P SA+H A +PF G RNCIG +FA Q +V + + RFE
Sbjct: 424 VWPNPEVFDPFRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNQLKV--ARALTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 111 bits (268), Expect = 3e-24
Identities = 65/187 (34%), Positives = 98/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP RF+P SA+H A +PF G RNCIG +FA + +V + RFE
Sbjct: 424 VWPNPEVFDPSRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNELKVATA--LTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 111 bits (268), Expect = 3e-24
Identities = 65/187 (34%), Positives = 98/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP RF+P SA+H A +PF G RNCIG +FA + +V + RFE
Sbjct: 424 VWPNPEVFDPSRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNELKVATA--LTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 519
Score = 111 bits (268), Expect = 3e-24
Identities = 66/187 (35%), Positives = 98/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI GL +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEI-HGLLGDGASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PN FDP RF+P SA+H A +PF G RNCIG +FA Q +V + + RFE
Sbjct: 424 VWPNLEVFDPSRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNQLKV--ARALTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 111 bits (268), Expect = 3e-24
Identities = 66/187 (35%), Positives = 98/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI GL +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEI-HGLLGDGASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PN FDP RF+P SA+H A +PF G RNCIG +FA Q +V + + RFE
Sbjct: 424 VWPNLEVFDPSRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNQLKV--ARALTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 110 bits (265), Expect = 6e-24
Identities = 65/187 (34%), Positives = 98/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP RF+P SA+H A +PF G RNCIG +FA + +V + RFE
Sbjct: 424 VWPNPEVFDPFRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNELKVATA--LTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 110 bits (265), Expect = 6e-24
Identities = 65/187 (34%), Positives = 98/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP RF+P SA+H A +PF G RNCIG +FA + +V + RFE
Sbjct: 424 VWPNPEVFDPFRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNELKVATA--LTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 110 bits (265), Expect = 6e-24
Identities = 65/187 (34%), Positives = 98/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP RF+P SA+H A +PF G RNCIG +FA + +V + RFE
Sbjct: 424 VWPNPEVFDPFRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNELKVATA--LTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 110 bits (265), Expect = 6e-24
Identities = 65/187 (34%), Positives = 98/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP RF+P SA+H A +PF G RNCIG +FA + +V + RFE
Sbjct: 424 VWPNPEVFDPFRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNELKVATA--LTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 110 bits (264), Expect = 9e-24
Identities = 65/187 (34%), Positives = 99/187 (52%), Gaps = 5/187 (2%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 307 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 365
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 366 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 424
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP RF+P SA+H A +PF G RNCIG +FA + +V + + RFE
Sbjct: 425 VWPNPEVFDPFRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNELKVGQ-QALTLVRFE 481
Query: 332 LAKNTPR 338
L + R
Sbjct: 482 LLPDPTR 488
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 109 bits (261), Expect = 2e-23
Identities = 64/187 (34%), Positives = 98/187 (52%), Gaps = 6/187 (3%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR++ V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP RF+P SA+H A +PF G RNCIG +FA + +V + RFE
Sbjct: 424 VWPNPEVFDPFRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNELKVATA--LTLLRFE 479
Query: 332 LAKNTPR 338
L + R
Sbjct: 480 LLPDPTR 486
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 108 bits (260), Expect = 3e-23
Identities = 52/135 (38%), Positives = 77/135 (57%), Gaps = 3/135 (2%)
Query: 209 TYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHH 268
TY+ + + Y + NETLR++ + L+R K D +I + I KG+ V+ +HH
Sbjct: 17 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYALHH 74
Query: 269 DEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
D KY+ P +F PERFS S P + PFGTGPRNCIGMRFA + ++ ++++ F
Sbjct: 75 DPKYWTEPEEFRPERFSKKKDSI-DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 133
Query: 329 RFELAKNTPRNLDID 343
F+ K T L +D
Sbjct: 134 SFKPCKETQIPLKLD 148
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 108 bits (260), Expect = 3e-23
Identities = 52/135 (38%), Positives = 77/135 (57%), Gaps = 3/135 (2%)
Query: 209 TYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHH 268
TY+ + + Y + NETLR++ + L+R K D +I + I KG+ V+ +HH
Sbjct: 4 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYALHH 61
Query: 269 DEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
D KY+ P +F PERFS S P + PFGTGPRNCIGMRFA + ++ ++++ F
Sbjct: 62 DPKYWTEPEEFRPERFSKKKDSI-DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 120
Query: 329 RFELAKNTPRNLDID 343
F+ K T L +D
Sbjct: 121 SFKPCKETQIPLKLD 135
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 107 bits (256), Expect = 8e-23
Identities = 54/143 (37%), Positives = 85/143 (59%), Gaps = 3/143 (2%)
Query: 141 RNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQG 200
+NS++ + L+D + AQ+ + A Y+T++TT+ F++Y+LA +PD+Q K+ EID
Sbjct: 139 QNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAV 198
Query: 201 LKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVL 260
L +K VTY+ L + Y + NETLR++ +V + R K D +I + I KG V+
Sbjct: 199 L-PNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--NGVFIPKGLAVM 255
Query: 261 FSPLGIHHDEKYYPNPSKFDPER 283
+HHD KY+ P KF PER
Sbjct: 256 VPIYALHHDPKYWTEPEKFCPER 278
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 106 bits (254), Expect = 1e-22
Identities = 90/341 (26%), Positives = 158/341 (46%), Gaps = 36/341 (10%)
Query: 10 NKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFG----LDIDTT-DPNKDQLKTLEE 64
NK+ EH+ ++ V T+ +I CAF + +D+T D + L +
Sbjct: 165 NKWEEHIAQ----NSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSK 220
Query: 65 IDRLSLTANFAFELDMMYP-----GVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTD 119
I + NF D+++ + K N L F + +D +++ ++ T
Sbjct: 221 ISNQRMN-NFLHHNDLVFKFSSQGQIFSKFNQELHQ-FTEKVIQDRKESLKDKLKQDTTQ 278
Query: 120 RN--DFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
+ DF+D++L+ A N++D ++ ++A+ F AG++T+++ ++
Sbjct: 279 KRRWDFLDILLS--------AKSENTKD------FSEADLQAEVKTFMFAGHDTTSSAIS 324
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LA P+ Q + EI + L + +T+E L + Y E LR+Y+ V +
Sbjct: 325 WILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNIS 383
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R PD + G TV + +HH+ ++ +P F+P RFS N HP A
Sbjct: 384 RLLDKPITFPDGRS-LPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAF 442
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
IPF G RNCIG FA I+ +V + + RF+LA + R
Sbjct: 443 IPFSAGLRNCIGQHFAIIECKVAVA--LTLLRFKLAPDHSR 481
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 106 bits (254), Expect = 1e-22
Identities = 90/341 (26%), Positives = 158/341 (46%), Gaps = 36/341 (10%)
Query: 10 NKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFG----LDIDTT-DPNKDQLKTLEE 64
NK+ EH+ ++ V T+ +I CAF + +D+T D + L +
Sbjct: 165 NKWEEHIAQ----NSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSK 220
Query: 65 IDRLSLTANFAFELDMMYP-----GVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTD 119
I + NF D+++ + K N L F + +D +++ ++ T
Sbjct: 221 ISNQRMN-NFLHHNDLVFKFSSQGQIFSKFNQELHQ-FTEKVIQDRKESLKDKLKQDTTQ 278
Query: 120 RN--DFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
+ DF+D++L+ A N++D ++ ++A+ F AG++T+++ ++
Sbjct: 279 KRRWDFLDILLS--------AKSENTKD------FSEADLQAEVKTFMFAGHDTTSSAIS 324
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LA P+ Q + EI + L + +T+E L + Y E LR+Y+ V +
Sbjct: 325 WILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNIS 383
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R PD + G TV + +HH+ ++ +P F+P RFS N HP A
Sbjct: 384 RLLDKPITFPDGRS-LPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAF 442
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
IPF G RNCIG FA I+ +V + + RF+LA + R
Sbjct: 443 IPFSAGLRNCIGQHFAIIECKVAVA--LTLLRFKLAPDHSR 481
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 106 bits (254), Expect = 1e-22
Identities = 90/341 (26%), Positives = 158/341 (46%), Gaps = 36/341 (10%)
Query: 10 NKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFG----LDIDTT-DPNKDQLKTLEE 64
NK+ EH+ ++ V T+ +I CAF + +D+T D + L +
Sbjct: 165 NKWEEHIAQ----NSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSK 220
Query: 65 IDRLSLTANFAFELDMMYP-----GVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTD 119
I + NF D+++ + K N L F + +D +++ ++ T
Sbjct: 221 ISNQRMN-NFLHHNDLVFKFSSQGQIFSKFNQELHQ-FTEKVIQDRKESLKDKLKQDTTQ 278
Query: 120 RN--DFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
+ DF+D++L+ A N++D ++ ++A+ F AG++T+++ ++
Sbjct: 279 KRRWDFLDILLS--------AKSENTKD------FSEADLQAEVKTFMFAGHDTTSSAIS 324
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LA P+ Q + EI + L + +T+E L + Y E LR+Y+ V +
Sbjct: 325 WILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNIS 383
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R PD + G TV + +HH+ ++ +P F+P RFS N HP A
Sbjct: 384 RLLDKPITFPDGRS-LPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAF 442
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
IPF G RNCIG FA I+ +V + + RF+LA + R
Sbjct: 443 IPFSAGLRNCIGQHFAIIECKVAVA--LTLLRFKLAPDHSR 481
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 106 bits (254), Expect = 1e-22
Identities = 90/341 (26%), Positives = 158/341 (46%), Gaps = 36/341 (10%)
Query: 10 NKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFG----LDIDTT-DPNKDQLKTLEE 64
NK+ EH+ ++ V T+ +I CAF + +D+T D + L +
Sbjct: 165 NKWEEHIAQ----NSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSK 220
Query: 65 IDRLSLTANFAFELDMMYP-----GVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTD 119
I + NF D+++ + K N L F + +D +++ ++ T
Sbjct: 221 ISNQRMN-NFLHHNDLVFKFSSQGQIFSKFNQELHQ-FTEKVIQDRKESLKDKLKQDTTQ 278
Query: 120 RN--DFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMT 177
+ DF+D++L+ A N++D ++ ++A+ F AG++T+++ ++
Sbjct: 279 KRRWDFLDILLS--------AKSENTKD------FSEADLQAEVKTFMFAGHDTTSSAIS 324
Query: 178 FMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQ 237
++LY LA P+ Q + EI + L + +T+E L + Y E LR+Y+ V +
Sbjct: 325 WILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNIS 383
Query: 238 RNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH 297
R PD + G TV + +HH+ ++ +P F+P RFS N HP A
Sbjct: 384 RLLDKPITFPDGRS-LPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAF 442
Query: 298 IPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPR 338
IPF G RNCIG FA I+ +V + + RF+LA + R
Sbjct: 443 IPFSAGLRNCIGQHFAIIECKVAVA--LTLLRFKLAPDHSR 481
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 99.5 bits (237), Expect = 2e-20
Identities = 53/144 (36%), Positives = 77/144 (53%), Gaps = 4/144 (2%)
Query: 164 FYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAF 223
F G++T+A+ ++++LY LA +P Q++ EI GL +T+ L + Y
Sbjct: 2 FMFEGHDTTASGISWILYALATHPKHQERCREEI-HGLLGDGASITWNHLDQMPYTTMCI 60
Query: 224 NETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPER 283
E LR+Y V + R PD + KG TV+ S G+HH+ K +PNP FDP R
Sbjct: 61 KEALRLYPPVPGISRELSTPVTFPDGRS-LPKGITVMLSIYGLHHNPKVWPNPEVFDPSR 119
Query: 284 FSPANISARHPCAHIPFGTGPRNC 307
F+P SA+H A +PF G RNC
Sbjct: 120 FAPG--SAQHSHAFLPFSGGSRNC 141
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 295 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 353
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 354 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 412
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 413 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 472
Query: 327 KFRFEL 332
+F F L
Sbjct: 473 RFEFSL 478
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 295 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 353
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 354 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 412
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 413 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 472
Query: 327 KFRFEL 332
+F F L
Sbjct: 473 RFEFSL 478
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 295 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 353
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 354 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 412
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 413 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 472
Query: 327 KFRFEL 332
+F F L
Sbjct: 473 RFEFSL 478
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 296 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 354
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 355 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 413
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 414 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 473
Query: 327 KFRFEL 332
+F F L
Sbjct: 474 RFEFSL 479
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 281 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 339
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 340 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 398
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 399 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 458
Query: 327 KFRFEL 332
+F F L
Sbjct: 459 RFEFSL 464
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 296 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 354
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 355 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 413
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 414 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 473
Query: 327 KFRFEL 332
+F F L
Sbjct: 474 RFEFSL 479
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 295 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 353
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 354 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 412
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 413 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 472
Query: 327 KFRFEL 332
+F F L
Sbjct: 473 RFEFSL 478
>AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 281 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 339
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 340 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 398
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 399 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 458
Query: 327 KFRFEL 332
+F F L
Sbjct: 459 RFEFSL 464
>AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 296 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 354
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 355 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 413
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 414 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 473
Query: 327 KFRFEL 332
+F F L
Sbjct: 474 RFEFSL 479
>AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 295 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 353
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 354 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 412
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 413 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 472
Query: 327 KFRFEL 332
+F F L
Sbjct: 473 RFEFSL 478
>AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 295 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 353
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 354 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 412
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 413 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 472
Query: 327 KFRFEL 332
+F F L
Sbjct: 473 RFEFSL 478
>AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 296 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 354
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 355 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 413
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 414 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 473
Query: 327 KFRFEL 332
+F F L
Sbjct: 474 RFEFSL 479
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 281 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD-QD 339
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 340 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 398
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 399 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 458
Query: 327 KFRFEL 332
+F F L
Sbjct: 459 RFEFSL 464
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 97.9 bits (233), Expect = 5e-20
Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ + +++ LY +AL P+ Q + E+ + L + +
Sbjct: 295 EDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCIALYPEHQHRCREEVREILGD-QD 353
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 354 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 412
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 413 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 472
Query: 327 KFRFEL 332
+F F L
Sbjct: 473 RFEFSL 478
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 96.7 bits (230), Expect = 1e-19
Identities = 55/186 (29%), Positives = 90/186 (48%), Gaps = 2/186 (1%)
Query: 147 EYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKG 206
E I+L+D + A+ F G++T+ +++ LY +AL P+ Q + E+ + L + +
Sbjct: 295 EDDIKLSDADLRAEVDTFMFEGHDTTTGGISWFLYCMALYPEHQHRCREEVREILGD-QD 353
Query: 207 EVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGI 266
++ L +TY E+ R+Y V + R D + G+ + +
Sbjct: 354 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS-LPAGSLISMHIYAL 412
Query: 267 HHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFS 326
H + +P+P FD RFS N S RHP A +PF GPRNCIG +FA + +V
Sbjct: 413 HRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 472
Query: 327 KFRFEL 332
+F F L
Sbjct: 473 RFEFSL 478
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 96.3 bits (229), Expect = 1e-19
Identities = 84/326 (25%), Positives = 148/326 (45%), Gaps = 22/326 (6%)
Query: 7 ERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEID 66
E+A + +E +E D Q + ++ M +A AFG++ + L ++
Sbjct: 159 EKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLM 218
Query: 67 RLSLTANFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDL 126
+TA+ L PG K+L RF + V + + QR + R + +
Sbjct: 219 LEGITAS-RNTLAKFLPGKRKQLREVRES---IRFLRQVGRDWV-QRRREALKRGEEVPA 273
Query: 127 ILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALN 186
+ L I + ++D E L D + F+IAG+ETSA + F + +L+
Sbjct: 274 DI----LTQILKAEEGAQDDE---GLLDNFV-----TFFIAGHETSANHLAFTVMELSRQ 321
Query: 187 PDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKI 246
P+I ++ AE+D+ + SK + +E L L Y + E+LR+Y R + + I
Sbjct: 322 PEIVARLQAEVDEVI-GSKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI 380
Query: 247 PDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRN 306
+ + T +LFS + + Y+ +P F+P+RF P R + PF G R+
Sbjct: 381 --DGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPRF--TYFPFSLGHRS 436
Query: 307 CIGMRFAKIQSRVCMVKMFSKFRFEL 332
CIG +FA+++ +V M K+ + F L
Sbjct: 437 CIGQQFAQMEVKVVMAKLLQRLEFRL 462
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 96.3 bits (229), Expect = 1e-19
Identities = 84/326 (25%), Positives = 148/326 (45%), Gaps = 22/326 (6%)
Query: 7 ERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEID 66
E+A + +E +E D Q + ++ M +A AFG++ + L ++
Sbjct: 159 EKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLM 218
Query: 67 RLSLTANFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDL 126
+TA+ L PG K+L RF + V + + QR + R + +
Sbjct: 219 LEGITAS-RNTLAKFLPGKRKQLREVRES---IRFLRQVGRDWV-QRRREALKRGEEVPA 273
Query: 127 ILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALN 186
+ L I + ++D E L D + F+IAG+ETSA + F + +L+
Sbjct: 274 DI----LTQILKAEEGAQDDE---GLLDNFV-----TFFIAGHETSANHLAFTVMELSRQ 321
Query: 187 PDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKI 246
P+I ++ AE+D+ + SK + +E L L Y + E+LR+Y R + + I
Sbjct: 322 PEIVARLQAEVDEVI-GSKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI 380
Query: 247 PDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRN 306
+ + T +LFS + + Y+ +P F+P+RF P R + PF G R+
Sbjct: 381 --DGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPRF--TYFPFSLGHRS 436
Query: 307 CIGMRFAKIQSRVCMVKMFSKFRFEL 332
CIG +FA+++ +V M K+ + F L
Sbjct: 437 CIGQQFAQMEVKVVMAKLLQRLEFRL 462
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 93.1 bits (221), Expect = 1e-18
Identities = 53/154 (34%), Positives = 81/154 (52%), Gaps = 4/154 (2%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPR 305
+PNP FDP RF+P SA+H A +PF G R
Sbjct: 424 VWPNPEVFDPFRFAPG--SAQHSHAFLPFSGGSR 455
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 93.1 bits (221), Expect = 1e-18
Identities = 53/154 (34%), Positives = 81/154 (52%), Gaps = 4/154 (2%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI L + +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDG-ASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPR 305
+PNP FDP RF+P SA+H A +PF G R
Sbjct: 424 VWPNPEVFDPFRFAPG--SAQHSHAFLPFSGGSR 455
>M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase
protein.
Length = 460
Score = 92.3 bits (219), Expect = 2e-18
Identities = 78/310 (25%), Positives = 133/310 (42%), Gaps = 30/310 (9%)
Query: 1 MLHLMIERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDT----TDPNK 56
M+ L+ + + + H++ + DI YT +A+ FG +D+ DP
Sbjct: 152 MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFV 211
Query: 57 DQLKTLEE--IDRLSLTANFAFELDMM-YPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQR 113
K E I R L +F M+ +L N GF ++ ++V+ + +
Sbjct: 212 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIA--LRDQ 269
Query: 114 NGKPTDRNDFMDLILALRQ------------LGDIQAT-------KRNSEDKEYSIELTD 154
R DF+ ++L R + D+ ++ R + + LT
Sbjct: 270 QAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 329
Query: 155 ELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQ 214
+ I QAF+F IAGYE T++F Y LA NPD Q+K++ E+D ++ + +
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEE 389
Query: 215 NLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYP 274
L Y + ETLRMY R A D ++ I G + + +HHD +++P
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 275 NPSKFDPERF 284
+P F+PER+
Sbjct: 448 SPETFNPERY 457
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 87/324 (26%), Positives = 143/324 (44%), Gaps = 19/324 (5%)
Query: 17 EMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEE--IDRLSLTA- 72
+ML H + DI V I+ F DP + ++ E ID LS +
Sbjct: 155 DMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSL 214
Query: 73 -NFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALR 131
+ L + L+KL S + + D++ I+E N K R+D + +L
Sbjct: 215 VDLVPWLKIFPNKTLEKLKSHV------KIRNDLLNKILE--NYKEKFRSDSITNMLDTL 266
Query: 132 QLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQD 191
+ + N+ + S L+D I + AG ET+ + + + L L NP ++
Sbjct: 267 MQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKK 326
Query: 192 KVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPL-QRNAKIDYKIPDTD 250
K+ EIDQ + S+ T L E E LR+ + L A +D I +
Sbjct: 327 KLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGE-- 383
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF-SPANISARHP-CAHIPFGTGPRNCI 308
++KGT V+ + +HH+EK + P +F PERF +PA P +++PFG GPR+CI
Sbjct: 384 FAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
Query: 309 GMRFAKIQSRVCMVKMFSKFRFEL 332
G A+ + + M + +F E+
Sbjct: 444 GEILARQELFLIMAWLLQRFDLEV 467
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 87/324 (26%), Positives = 143/324 (44%), Gaps = 19/324 (5%)
Query: 17 EMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEE--IDRLSLTA- 72
+ML H + DI V I+ F DP + ++ E ID LS +
Sbjct: 155 DMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSL 214
Query: 73 -NFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALR 131
+ L + L+KL S + + D++ I+E N K R+D + +L
Sbjct: 215 VDLVPWLKIFPNKTLEKLKSHV------KIRNDLLNKILE--NYKEKFRSDSITNMLDTL 266
Query: 132 QLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQD 191
+ + N+ + S L+D I + AG ET+ + + + L L NP ++
Sbjct: 267 MQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKK 326
Query: 192 KVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPL-QRNAKIDYKIPDTD 250
K+ EIDQ + S+ T L E E LR+ + L A +D I +
Sbjct: 327 KLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGE-- 383
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF-SPANISARHP-CAHIPFGTGPRNCI 308
++KGT V+ + +HH+EK + P +F PERF +PA P +++PFG GPR+CI
Sbjct: 384 FAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
Query: 309 GMRFAKIQSRVCMVKMFSKFRFEL 332
G A+ + + M + +F E+
Sbjct: 444 GEILARQELFLIMAWLLQRFDLEV 467
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 87/324 (26%), Positives = 143/324 (44%), Gaps = 19/324 (5%)
Query: 17 EMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEE--IDRLSLTA- 72
+ML H + DI V I+ F DP + ++ E ID LS +
Sbjct: 155 DMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSL 214
Query: 73 -NFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALR 131
+ L + L+KL S + + D++ I+E N K R+D + +L
Sbjct: 215 VDLVPWLKIFPNKTLEKLKSHV------KIRNDLLNKILE--NYKEKFRSDSITNMLDTL 266
Query: 132 QLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQD 191
+ + N+ + S L+D I + AG ET+ + + + L L NP ++
Sbjct: 267 MQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKK 326
Query: 192 KVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPL-QRNAKIDYKIPDTD 250
K+ EIDQ + S+ T L E E LR+ + L A +D I +
Sbjct: 327 KLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGE-- 383
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF-SPANISARHP-CAHIPFGTGPRNCI 308
++KGT V+ + +HH+EK + P +F PERF +PA P +++PFG GPR+CI
Sbjct: 384 FAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
Query: 309 GMRFAKIQSRVCMVKMFSKFRFEL 332
G A+ + + M + +F E+
Sbjct: 444 GEILARQELFLIMAWLLQRFDLEV 467
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 87/324 (26%), Positives = 143/324 (44%), Gaps = 19/324 (5%)
Query: 17 EMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEE--IDRLSLTA- 72
+ML H + DI V I+ F DP + ++ E ID LS +
Sbjct: 155 DMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSL 214
Query: 73 -NFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALR 131
+ L + L+KL S + + D++ I+E N K R+D + +L
Sbjct: 215 VDLVPWLKIFPNKTLEKLKSHV------KIRNDLLNKILE--NYKEKFRSDSITNMLDTL 266
Query: 132 QLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQD 191
+ + N+ + S L+D I + AG ET+ + + + L L NP ++
Sbjct: 267 MQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKK 326
Query: 192 KVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPL-QRNAKIDYKIPDTD 250
K+ EIDQ + S+ T L E E LR+ + L A +D I +
Sbjct: 327 KLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGE-- 383
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF-SPANISARHP-CAHIPFGTGPRNCI 308
++KGT V+ + +HH+EK + P +F PERF +PA P +++PFG GPR+CI
Sbjct: 384 FAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
Query: 309 GMRFAKIQSRVCMVKMFSKFRFEL 332
G A+ + + M + +F E+
Sbjct: 444 GEILARQELFLIMAWLLQRFDLEV 467
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 87/324 (26%), Positives = 143/324 (44%), Gaps = 19/324 (5%)
Query: 17 EMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEE--IDRLSLTA- 72
+ML H + DI V I+ F DP + ++ E ID LS +
Sbjct: 155 DMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSL 214
Query: 73 -NFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALR 131
+ L + L+KL S + + D++ I+E N K R+D + +L
Sbjct: 215 VDLVPWLKIFPNKTLEKLKSHV------KIRNDLLNKILE--NYKEKFRSDSITNMLDTL 266
Query: 132 QLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQD 191
+ + N+ + S L+D I + AG ET+ + + + L L NP ++
Sbjct: 267 MQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKK 326
Query: 192 KVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPL-QRNAKIDYKIPDTD 250
K+ EIDQ + S+ T L E E LR+ + L A +D I +
Sbjct: 327 KLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGE-- 383
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF-SPANISARHP-CAHIPFGTGPRNCI 308
++KGT V+ + +HH+EK + P +F PERF +PA P +++PFG GPR+CI
Sbjct: 384 FAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
Query: 309 GMRFAKIQSRVCMVKMFSKFRFEL 332
G A+ + + M + +F E+
Sbjct: 444 GEILARQELFLIMAWLLQRFDLEV 467
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 87/324 (26%), Positives = 143/324 (44%), Gaps = 19/324 (5%)
Query: 17 EMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEE--IDRLSLTA- 72
+ML H + DI V I+ F DP + ++ E ID LS +
Sbjct: 155 DMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSL 214
Query: 73 -NFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALR 131
+ L + L+KL S + + D++ I+E N K R+D + +L
Sbjct: 215 VDLVPWLKIFPNKTLEKLKSHV------KIRNDLLNKILE--NYKEKFRSDSITNMLDTL 266
Query: 132 QLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQD 191
+ + N+ + S L+D I + AG ET+ + + + L L NP ++
Sbjct: 267 MQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKK 326
Query: 192 KVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPL-QRNAKIDYKIPDTD 250
K+ EIDQ + S+ T L E E LR+ + L A +D I +
Sbjct: 327 KLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGE-- 383
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF-SPANISARHP-CAHIPFGTGPRNCI 308
++KGT V+ + +HH+EK + P +F PERF +PA P +++PFG GPR+CI
Sbjct: 384 FAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
Query: 309 GMRFAKIQSRVCMVKMFSKFRFEL 332
G A+ + + M + +F E+
Sbjct: 444 GEILARQELFLIMAWLLQRFDLEV 467
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 87/324 (26%), Positives = 143/324 (44%), Gaps = 19/324 (5%)
Query: 17 EMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEE--IDRLSLTA- 72
+ML H + DI V I+ F DP + ++ E ID LS +
Sbjct: 155 DMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSL 214
Query: 73 -NFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALR 131
+ L + L+KL S + + D++ I+E N K R+D + +L
Sbjct: 215 VDLVPWLKIFPNKTLEKLKSHV------KIRNDLLNKILE--NYKEKFRSDSITNMLDTL 266
Query: 132 QLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQD 191
+ + N+ + S L+D I + AG ET+ + + + L L NP ++
Sbjct: 267 MQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKK 326
Query: 192 KVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPL-QRNAKIDYKIPDTD 250
K+ EIDQ + S+ T L E E LR+ + L A +D I +
Sbjct: 327 KLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGE-- 383
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF-SPANISARHP-CAHIPFGTGPRNCI 308
++KGT V+ + +HH+EK + P +F PERF +PA P +++PFG GPR+CI
Sbjct: 384 FAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
Query: 309 GMRFAKIQSRVCMVKMFSKFRFEL 332
G A+ + + M + +F E+
Sbjct: 444 GEILARQELFLIMAWLLQRFDLEV 467
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 87/324 (26%), Positives = 143/324 (44%), Gaps = 19/324 (5%)
Query: 17 EMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEE--IDRLSLTA- 72
+ML H + DI V I+ F DP + ++ E ID LS +
Sbjct: 155 DMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSL 214
Query: 73 -NFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALR 131
+ L + L+KL S + + D++ I+E N K R+D + +L
Sbjct: 215 VDLVPWLKIFPNKTLEKLKSHV------KIRNDLLNKILE--NYKEKFRSDSITNMLDTL 266
Query: 132 QLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQD 191
+ + N+ + S L+D I + AG ET+ + + + L L NP ++
Sbjct: 267 MQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKK 326
Query: 192 KVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPL-QRNAKIDYKIPDTD 250
K+ EIDQ + S+ T L E E LR+ + L A +D I +
Sbjct: 327 KLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGE-- 383
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF-SPANISARHP-CAHIPFGTGPRNCI 308
++KGT V+ + +HH+EK + P +F PERF +PA P +++PFG GPR+CI
Sbjct: 384 FAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
Query: 309 GMRFAKIQSRVCMVKMFSKFRFEL 332
G A+ + + M + +F E+
Sbjct: 444 GEILARQELFLIMAWLLQRFDLEV 467
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 87/324 (26%), Positives = 143/324 (44%), Gaps = 19/324 (5%)
Query: 17 EMLCDHQPEQ-DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEE--IDRLSLTA- 72
+ML H + DI V I+ F DP + ++ E ID LS +
Sbjct: 155 DMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSL 214
Query: 73 -NFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALR 131
+ L + L+KL S + + D++ I+E N K R+D + +L
Sbjct: 215 VDLVPWLKIFPNKTLEKLKSHV------KIRNDLLNKILE--NYKEKFRSDSITNMLDTL 266
Query: 132 QLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQD 191
+ + N+ + S L+D I + AG ET+ + + + L L NP ++
Sbjct: 267 MQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKK 326
Query: 192 KVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPL-QRNAKIDYKIPDTD 250
K+ EIDQ + S+ T L E E LR+ + L A +D I +
Sbjct: 327 KLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGE-- 383
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF-SPANISARHP-CAHIPFGTGPRNCI 308
++KGT V+ + +HH+EK + P +F PERF +PA P +++PFG GPR+CI
Sbjct: 384 FAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
Query: 309 GMRFAKIQSRVCMVKMFSKFRFEL 332
G A+ + + M + +F E+
Sbjct: 444 GEILARQELFLIMAWLLQRFDLEV 467
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 92.3 bits (219), Expect = 2e-18
Identities = 53/154 (34%), Positives = 80/154 (51%), Gaps = 4/154 (2%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
L+D+ + A+ F G++T+A+ ++++LY LA +P Q++ EI GL +T+
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEI-HGLLGDGASITWN 364
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPK 423
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPR 305
+PN FDP RF+P SA+H A +PF G R
Sbjct: 424 VWPNLEVFDPSRFAPG--SAQHSHAFLPFSGGSR 455
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 89.8 bits (213), Expect = 1e-17
Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 9/253 (3%)
Query: 94 FPGFVSRFFKDV--VKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIE 151
FPG ++ K+V +K+ I + K + + MD+ + D K E E
Sbjct: 221 FPGTHNKLLKNVAFMKSYILE---KVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPSE 276
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
T E +E A + AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 277 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQD 336
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
++ Y + +E R ++ P + I + +I KGTT+L S + HD K
Sbjct: 337 R-SHMPYTDAVVHEVQRCIDLL-PTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNK 394
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP F + + +PF G R C+G A ++ + + + F +
Sbjct: 395 EFPNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLK 454
Query: 332 LAKNTPRNLDIDP 344
+ P+NLD P
Sbjct: 455 SLVD-PKNLDTTP 466
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 89.8 bits (213), Expect = 1e-17
Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 9/253 (3%)
Query: 94 FPGFVSRFFKDV--VKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIE 151
FPG ++ K+V +K+ I + K + + MD+ + D K E E
Sbjct: 221 FPGTHNKLLKNVAFMKSYILE---KVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPSE 276
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
T E +E A + AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 277 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQD 336
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
++ Y + +E R ++ P + I + +I KGTT+L S + HD K
Sbjct: 337 R-SHMPYTDAVVHEVQRCIDLL-PTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNK 394
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP F + + +PF G R C+G A ++ + + + F +
Sbjct: 395 EFPNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLK 454
Query: 332 LAKNTPRNLDIDP 344
+ P+NLD P
Sbjct: 455 SLVD-PKNLDTTP 466
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 89.4 bits (212), Expect = 2e-17
Identities = 87/342 (25%), Positives = 154/342 (45%), Gaps = 25/342 (7%)
Query: 7 ERANKYIEHVEMLCDHQPEQ--DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQL-KTLE 63
ER + +H+ + Q D H + I + FG + D QL K L+
Sbjct: 157 ERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLD 216
Query: 64 EIDRLSLTANFAFELDMMYPGVLKKL---NSTLFPGFVSRFFKDVVKTIIEQ--RNGKPT 118
E+ L A+ +L ++P ++K L + TLF + + K V +I++ ++ P
Sbjct: 217 EVTYLE--ASKTCQLYNVFPWIMKFLPGPHQTLFSNW--KKLKLFVSHMIDKHRKDWNPA 272
Query: 119 DRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTF 178
+ DF+D L +++ +S +E I T +L + AG ET++TT+ +
Sbjct: 273 ETRDFIDAYL--KEMSKHTGNPTSSFHEENLICSTLDL--------FFAGTETTSTTLRW 322
Query: 179 MLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQR 238
L +AL P+IQ+KV AEID+ + + + T +++ Y +E RM +I+ PL
Sbjct: 323 ALLYMALYPEIQEKVQAEIDRVIGQGQQPST-AARESMPYTNAVIHEVQRMGNII-PLNV 380
Query: 239 NAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHI 298
++ + KGT +L + +H D + P F+P+ F N + A +
Sbjct: 381 PREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFM 439
Query: 299 PFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPRNL 340
PF G R C+G + A+ + + + KF F N +L
Sbjct: 440 PFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSL 481
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 89.4 bits (212), Expect = 2e-17
Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 9/253 (3%)
Query: 94 FPGFVSRFFKDV--VKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIE 151
FPG ++ K+V +K+ I + K + + MD+ + D K E E
Sbjct: 213 FPGTHNKLLKNVAFMKSYILE---KVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPSE 268
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
T E +E A + AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 269 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQD 328
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
++ Y + +E R ++ P + I + +I KGTT+L S + HD K
Sbjct: 329 R-SHMPYTDAVVHEVQRYIDLL-PTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNK 386
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP F + + +PF G R C+G A ++ + + + F +
Sbjct: 387 EFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLK 446
Query: 332 LAKNTPRNLDIDP 344
+ P+NLD P
Sbjct: 447 SLVD-PKNLDTTP 458
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 89.4 bits (212), Expect = 2e-17
Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 9/253 (3%)
Query: 94 FPGFVSRFFKDV--VKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIE 151
FPG ++ K+V +K+ I + K + + MD+ + D K E E
Sbjct: 119 FPGTHNKLLKNVAFMKSYILE---KVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPSE 174
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
T E +E A + AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 175 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQD 234
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
++ Y + +E R ++ P + I + +I KGTT+L S + HD K
Sbjct: 235 R-SHMPYTDAVVHEVQRCIDLL-PTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNK 292
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP F + + +PF G R C+G A ++ + + + F +
Sbjct: 293 EFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLK 352
Query: 332 LAKNTPRNLDIDP 344
+ P+NLD P
Sbjct: 353 SLVD-PKNLDTTP 364
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 89.4 bits (212), Expect = 2e-17
Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 9/253 (3%)
Query: 94 FPGFVSRFFKDV--VKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIE 151
FPG ++ K+V +K+ I + K + + MD+ + D K E E
Sbjct: 223 FPGTHNKLLKNVAFMKSYILE---KVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPSE 278
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
T E +E A + AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 279 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQD 338
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
++ Y + +E R ++ P + I + +I KGTT+L S + HD K
Sbjct: 339 R-SHMPYTDAVVHEVQRYIDLL-PTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNK 396
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP F + + +PF G R C+G A ++ + + + F +
Sbjct: 397 EFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLK 456
Query: 332 LAKNTPRNLDIDP 344
+ P+NLD P
Sbjct: 457 SLVD-PKNLDTTP 468
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 89.4 bits (212), Expect = 2e-17
Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 9/253 (3%)
Query: 94 FPGFVSRFFKDV--VKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIE 151
FPG ++ K+V +K+ I + K + + MD+ + D K E E
Sbjct: 226 FPGTHNKLLKNVAFMKSYILE---KVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPSE 281
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
T E +E A + AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQD 341
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
++ Y + +E R ++ P + I + +I KGTT+L S + HD K
Sbjct: 342 R-SHMPYTDAVVHEVQRYIDLL-PTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNK 399
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP F + + +PF G R C+G A ++ + + + F +
Sbjct: 400 EFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLK 459
Query: 332 LAKNTPRNLDIDP 344
+ P+NLD P
Sbjct: 460 SLVD-PKNLDTTP 471
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 89.4 bits (212), Expect = 2e-17
Identities = 87/342 (25%), Positives = 154/342 (45%), Gaps = 25/342 (7%)
Query: 7 ERANKYIEHVEMLCDHQPEQ--DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQL-KTLE 63
ER + +H+ + Q D H + I + FG + D QL K L+
Sbjct: 157 ERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLD 216
Query: 64 EIDRLSLTANFAFELDMMYPGVLKKL---NSTLFPGFVSRFFKDVVKTIIEQ--RNGKPT 118
E+ L A+ +L ++P ++K L + TLF + + K V +I++ ++ P
Sbjct: 217 EVTYLE--ASKTCQLYNVFPWIMKFLPGPHQTLFSNW--KKLKLFVSHMIDKHRKDWNPA 272
Query: 119 DRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTF 178
+ DF+D L +++ +S +E I T +L + AG ET++TT+ +
Sbjct: 273 ETRDFIDAYL--KEMSKHTGNPTSSFHEENLICSTLDL--------FFAGTETTSTTLRW 322
Query: 179 MLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQR 238
L +AL P+IQ+KV AEID+ + + + T +++ Y +E RM +I+ PL
Sbjct: 323 ALLYMALYPEIQEKVQAEIDRVIGQGQQPST-AARESMPYTNAVIHEVQRMGNII-PLNV 380
Query: 239 NAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHI 298
++ + KGT +L + +H D + P F+P+ F N + A +
Sbjct: 381 PREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFM 439
Query: 299 PFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPRNL 340
PF G R C+G + A+ + + + KF F N +L
Sbjct: 440 PFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSL 481
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 89.4 bits (212), Expect = 2e-17
Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 9/253 (3%)
Query: 94 FPGFVSRFFKDV--VKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIE 151
FPG ++ K+V +K+ I + K + + MD+ + D K E E
Sbjct: 226 FPGTHNKLLKNVAFMKSYILE---KVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPSE 281
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
T E +E A + AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQD 341
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
++ Y + +E R ++ P + I + +I KGTT+L S + HD K
Sbjct: 342 R-SHMPYTDAVVHEVQRYIDLL-PTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNK 399
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP F + + +PF G R C+G A ++ + + + F +
Sbjct: 400 EFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLK 459
Query: 332 LAKNTPRNLDIDP 344
+ P+NLD P
Sbjct: 460 SLVD-PKNLDTTP 471
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 89.4 bits (212), Expect = 2e-17
Identities = 87/342 (25%), Positives = 154/342 (45%), Gaps = 25/342 (7%)
Query: 7 ERANKYIEHVEMLCDHQPEQ--DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQL-KTLE 63
ER + +H+ + Q D H + I + FG + D QL K L+
Sbjct: 157 ERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLD 216
Query: 64 EIDRLSLTANFAFELDMMYPGVLKKL---NSTLFPGFVSRFFKDVVKTIIEQ--RNGKPT 118
E+ L A+ +L ++P ++K L + TLF + + K V +I++ ++ P
Sbjct: 217 EVTYLE--ASKTCQLYNVFPWIMKFLPGPHQTLFSNW--KKLKLFVSHMIDKHRKDWNPA 272
Query: 119 DRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTF 178
+ DF+D L +++ +S +E I T +L + AG ET++TT+ +
Sbjct: 273 ETRDFIDAYL--KEMSKHTGNPTSSFHEENLICSTLDL--------FFAGTETTSTTLRW 322
Query: 179 MLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQR 238
L +AL P+IQ+KV AEID+ + + + T +++ Y +E RM +I+ PL
Sbjct: 323 ALLYMALYPEIQEKVQAEIDRVIGQGQQPST-AARESMPYTNAVIHEVQRMGNII-PLNV 380
Query: 239 NAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHI 298
++ + KGT +L + +H D + P F+P+ F N + A +
Sbjct: 381 PREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFM 439
Query: 299 PFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPRNL 340
PF G R C+G + A+ + + + KF F N +L
Sbjct: 440 PFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSL 481
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 89.4 bits (212), Expect = 2e-17
Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 9/253 (3%)
Query: 94 FPGFVSRFFKDV--VKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIE 151
FPG ++ K+V +K+ I + K + + MD+ + D K E E
Sbjct: 226 FPGTHNKLLKNVAFMKSYILE---KVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPSE 281
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
T E +E A + AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQD 341
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
++ Y + +E R ++ P + I + +I KGTT+L S + HD K
Sbjct: 342 R-SHMPYTDAVVHEVQRYIDLL-PTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNK 399
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP F + + +PF G R C+G A ++ + + + F +
Sbjct: 400 EFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLK 459
Query: 332 LAKNTPRNLDIDP 344
+ P+NLD P
Sbjct: 460 SLVD-PKNLDTTP 471
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 89.4 bits (212), Expect = 2e-17
Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 9/253 (3%)
Query: 94 FPGFVSRFFKDV--VKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIE 151
FPG ++ K+V +K+ I + K + + MD+ + D K E E
Sbjct: 226 FPGTHNKLLKNVAFMKSYILE---KVKEHQESMDMNNP-QDFIDCFLMKMEKEKHNQPSE 281
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
T E +E A + AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQD 341
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
++ Y + +E R ++ P + I + +I KGTT+L S + HD K
Sbjct: 342 R-SHMPYTDAVVHEVQRYIDLL-PTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNK 399
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+PNP FDP F + + +PF G R C+G A ++ + + + F +
Sbjct: 400 EFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLK 459
Query: 332 LAKNTPRNLDIDP 344
+ P+NLD P
Sbjct: 460 SLVD-PKNLDTTP 471
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 89.4 bits (212), Expect = 2e-17
Identities = 87/342 (25%), Positives = 154/342 (45%), Gaps = 25/342 (7%)
Query: 7 ERANKYIEHVEMLCDHQPEQ--DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQL-KTLE 63
ER + +H+ + Q D H + I + FG + D QL K L+
Sbjct: 157 ERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLD 216
Query: 64 EIDRLSLTANFAFELDMMYPGVLKKL---NSTLFPGFVSRFFKDVVKTIIEQ--RNGKPT 118
E+ L A+ +L ++P ++K L + TLF + + K V +I++ ++ P
Sbjct: 217 EVTYLE--ASKTCQLYNVFPWIMKFLPGPHQTLFSNW--KKLKLFVSHMIDKHRKDWNPA 272
Query: 119 DRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTF 178
+ DF+D L +++ +S +E I T +L + AG ET++TT+ +
Sbjct: 273 ETRDFIDAYL--KEMSKHTGNPTSSFHEENLICSTLDL--------FFAGTETTSTTLRW 322
Query: 179 MLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQR 238
L +AL P+IQ+KV AEID+ + + + T +++ Y +E RM +I+ PL
Sbjct: 323 ALLYMALYPEIQEKVQAEIDRVIGQGQQPST-AARESMPYTNAVIHEVQRMGNII-PLNV 380
Query: 239 NAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHI 298
++ + KGT +L + +H D + P F+P+ F N + A +
Sbjct: 381 PREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFM 439
Query: 299 PFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPRNL 340
PF G R C+G + A+ + + + KF F N +L
Sbjct: 440 PFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSL 481
>AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
Homo sapiens cholesterol 24-hydroxylase mRNA. ).
Length = 337
Score = 89.0 bits (211), Expect = 2e-17
Identities = 81/326 (24%), Positives = 149/326 (45%), Gaps = 32/326 (9%)
Query: 7 ERANKYIEHVEMLCDHQPEQDIHTLVQKYTMATIAACAFGLDIDTTDPNKDQLKTLEEID 66
E+A + +E +E D Q + ++ M +A AFG++ + L ++
Sbjct: 6 EKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLM 65
Query: 67 RLSLTANFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDL 126
+TA+ L PG K+L RF + V + + QR + R + +
Sbjct: 66 LEGITAS-RNTLAKFLPGKRKQLREVRES---IRFLRQVGRDWV-QRRREALKRGEEVPA 120
Query: 127 ILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALN 186
+ L I + ++D E L D + F+IAG+ETSA + F + +L+
Sbjct: 121 DI----LTQILKAEEGAQDDE---GLLDNFV-----TFFIAGHETSANHLAFTVMELSRQ 168
Query: 187 PDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKI 246
P+I ++ AE+D+ + SK + +E L L Y + E+LR+Y A +++
Sbjct: 169 PEIVARLQAEVDEVI-GSKRYLDFEDLGRLQYLSQVLKESLRLYP-------PAWGTFRL 220
Query: 247 PDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRN 306
+ + +I+ +T + + + Y+ +P F+P+RF P R + PF G R+
Sbjct: 221 LEEETLIDGFSTYVMGRM-----DTYFEDPLTFNPDRFGPGAPKPRF--TYFPFSLGHRS 273
Query: 307 CIGMRFAKIQSRVCMVKMFSKFRFEL 332
CIG +FA+++ +V M K+ + F L
Sbjct: 274 CIGQQFAQMEVKVVMAKLLQRLEFRL 299
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 87.8 bits (208), Expect = 5e-17
Identities = 86/342 (25%), Positives = 153/342 (44%), Gaps = 25/342 (7%)
Query: 7 ERANKYIEHVEMLCDHQPEQ--DIHTLVQKYTMATIAACAFGLDIDTTDPNKDQL-KTLE 63
ER + +H+ + Q D H + I + FG + D QL K L+
Sbjct: 157 ERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLD 216
Query: 64 EIDRLSLTANFAFELDMMYPGVLKKL---NSTLFPGFVSRFFKDVVKTIIEQ--RNGKPT 118
E+ L A+ +L ++P ++K L + TLF + + K V +I++ ++ P
Sbjct: 217 EVTYLE--ASKTCQLYNVFPWIMKFLPGPHQTLFSNW--KKLKLFVSHMIDKHRKDWNPA 272
Query: 119 DRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTF 178
+ DF+D L +++ +S +E I T +L + AG ET++TT+ +
Sbjct: 273 ETRDFIDAYL--KEMSKHTGNPTSSFHEENLICSTLDL--------FFAGTETTSTTLRW 322
Query: 179 MLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQR 238
L +AL P+IQ+KV EID+ + + + T +++ Y +E RM +I+ PL
Sbjct: 323 ALLYMALYPEIQEKVQVEIDRVIGQGQQPST-AARESMPYTNAVIHEVQRMGNII-PLNV 380
Query: 239 NAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHI 298
++ + KGT +L + +H D + P F+P+ F N + A +
Sbjct: 381 PREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFM 439
Query: 299 PFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTPRNL 340
PF G R C+G + A+ + + + KF F N +L
Sbjct: 440 PFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSL 481
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 85.8 bits (203), Expect = 2e-16
Identities = 78/311 (25%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYKD--KEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQ 239
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +I G ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V + LG + D ++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-YPMLGSVLRDPSFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G RNC G A+++ + + FR + +
Sbjct: 406 SNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 465 SQSPKDIDVSP 475
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 85.8 bits (203), Expect = 2e-16
Identities = 78/311 (25%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 136 ISSIVFGDRFDYKD--KEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQ 193
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 194 LLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 243
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +I G ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 244 NLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 302
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V + LG + D ++
Sbjct: 303 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-YPMLGSVLRDPSFF 359
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G RNC G A+++ + + FR + +
Sbjct: 360 SNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-S 418
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 419 SQSPKDIDVSP 429
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 85.8 bits (203), Expect = 2e-16
Identities = 50/172 (29%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
+A ET+A ++ ++LY L+ NP +Q K++ EI L E++ E L+N+ Y + E
Sbjct: 68 LAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKE 126
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFS 285
++R+ V R +D + + KGT ++ + + E + + S+F PER+
Sbjct: 127 SMRLTPSVPFTTRT--LDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWL 184
Query: 286 PANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTP 337
+P AH+PFG G R CIG R A++Q + + + K+ + N P
Sbjct: 185 QEKEKI-NPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEP 235
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 85.8 bits (203), Expect = 2e-16
Identities = 78/311 (25%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYKD--KEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQ 239
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +I G ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V + LG + D ++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-YPMLGSVLRDPSFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G RNC G A+++ + + FR + +
Sbjct: 406 SNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 465 SQSPKDIDVSP 475
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 85.8 bits (203), Expect = 2e-16
Identities = 50/172 (29%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
+A ET+A ++ ++LY L+ NP +Q K++ EI L E++ E L+N+ Y + E
Sbjct: 324 LAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQ-RPREEDLRNMPYLKACLKE 382
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFS 285
++R+ V R +D + + KGT ++ + + E + + S+F PER+
Sbjct: 383 SMRLTPGVPFTTRT--LDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWL 440
Query: 286 PANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTP 337
+P AH+PFG G R CIG R A++Q + + + K+ + N P
Sbjct: 441 QEKEKI-NPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEP 491
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 85.8 bits (203), Expect = 2e-16
Identities = 79/311 (25%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYED--KEFLSLLSVMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFK 239
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +IAG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V F LG + D ++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-FPMLGSVLRDPSFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G R C G A+++ + + FR + +
Sbjct: 406 SNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 465 SQSPKDIDVSP 475
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 85.8 bits (203), Expect = 2e-16
Identities = 78/311 (25%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYKD--KEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQ 239
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +I G ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V + LG + D ++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-YPMLGSVLRDPSFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G RNC G A+++ + + FR + +
Sbjct: 406 SNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 465 SQSPKDIDVSP 475
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 85.8 bits (203), Expect = 2e-16
Identities = 78/311 (25%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYKD--KEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQ 239
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +I G ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V + LG + D ++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-YPMLGSVLRDPSFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G RNC G A+++ + + FR + +
Sbjct: 406 SNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 465 SQSPKDIDVSP 475
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 85.8 bits (203), Expect = 2e-16
Identities = 78/311 (25%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYKD--KEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQ 239
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +I G ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V + LG + D ++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-YPMLGSVLRDPSFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G RNC G A+++ + + FR + +
Sbjct: 406 SNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 465 SQSPKDIDVSP 475
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 85.8 bits (203), Expect = 2e-16
Identities = 78/311 (25%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYKD--KEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQ 239
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +I G ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V + LG + D ++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-YPMLGSVLRDPSFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G RNC G A+++ + + FR + +
Sbjct: 406 SNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 465 SQSPKDIDVSP 475
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 85.8 bits (203), Expect = 2e-16
Identities = 50/172 (29%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
+A ET+A ++ ++LY L+ NP +Q K++ EI L E++ E L+N+ Y + E
Sbjct: 183 LAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKE 241
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFS 285
++R+ V R +D + + KGT ++ + + E + + S+F PER+
Sbjct: 242 SMRLTPSVPFTTRT--LDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWL 299
Query: 286 PANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTP 337
+P AH+PFG G R CIG R A++Q + + + K+ + N P
Sbjct: 300 QEKEKI-NPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEP 350
>AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 85.8 bits (203), Expect = 2e-16
Identities = 50/172 (29%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
+A ET+A ++ ++LY L+ NP +Q K++ EI L E++ E L+N+ Y + E
Sbjct: 325 LAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKE 383
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFS 285
++R+ V R +D + + KGT ++ + + E + + S+F PER+
Sbjct: 384 SMRLTPSVPFTTRT--LDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWL 441
Query: 286 PANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTP 337
+P AH+PFG G R CIG R A++Q + + + K+ + N P
Sbjct: 442 QEKEKI-NPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEP 492
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 85.8 bits (203), Expect = 2e-16
Identities = 50/172 (29%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
+A ET+A ++ ++LY L+ NP +Q K++ EI L E++ E L+N+ Y + E
Sbjct: 183 LAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKE 241
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFS 285
++R+ V R +D + + KGT ++ + + E + + S+F PER+
Sbjct: 242 SMRLTPSVPFTTRT--LDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWL 299
Query: 286 PANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTP 337
+P AH+PFG G R CIG R A++Q + + + K+ + N P
Sbjct: 300 QEKEKI-NPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEP 350
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 85.8 bits (203), Expect = 2e-16
Identities = 78/311 (25%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYKD--KEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQ 239
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +I G ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V + LG + D ++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-YPMLGSVLRDPSFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G RNC G A+++ + + FR + +
Sbjct: 406 SNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 465 SQSPKDIDVSP 475
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 84.2 bits (199), Expect = 6e-16
Identities = 77/311 (24%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 177 ISSIVFGDRFDYKD--KEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQ 234
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 235 LLQGLEDFIAKKVEHKQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 284
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +I G ET +TT+ + L +P+++ +V EID+ + +++ + +E
Sbjct: 285 NLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAQVHEEIDRVIGKNR-QPKFEDRAK 343
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V + LG + D ++
Sbjct: 344 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-YPMLGSVLRDPSFF 400
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G RNC G A+++ + + FR + +
Sbjct: 401 SNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-S 459
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 460 SQSPKDIDVSP 470
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 84.2 bits (199), Expect = 6e-16
Identities = 63/243 (25%), Positives = 111/243 (45%), Gaps = 13/243 (5%)
Query: 98 VSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELI 157
++ F K ++K Q + + DF+D+ L L + + +S D+EY + +L
Sbjct: 294 ITSFLKKIIKD--HQESLDRENPQDFIDMYL-LHMEEERKNNSNSSFDEEYLFYIIGDL- 349
Query: 158 EAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLT 217
+IAG +T+ ++ + L ++LNPD+Q+KV EI++ + ++ + Q +
Sbjct: 350 -------FIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQ-MP 401
Query: 218 YFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPS 277
Y E E R+ ++V PL I KGT +L + +H D + P
Sbjct: 402 YTEATIMEVQRL-TVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPE 460
Query: 278 KFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTP 337
F P RF IPFG G R C+G + AK++ + V + F F L +++
Sbjct: 461 DFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSK 520
Query: 338 RNL 340
+ L
Sbjct: 521 KPL 523
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 84.2 bits (199), Expect = 6e-16
Identities = 63/243 (25%), Positives = 111/243 (45%), Gaps = 13/243 (5%)
Query: 98 VSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDELI 157
++ F K ++K Q + + DF+D+ L L + + +S D+EY + +L
Sbjct: 294 ITSFLKKIIKD--HQESLDRENPQDFIDMYL-LHMEEERKNNSNSSFDEEYLFYIIGDL- 349
Query: 158 EAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLT 217
+IAG +T+ ++ + L ++LNPD+Q+KV EI++ + ++ + Q +
Sbjct: 350 -------FIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQ-MP 401
Query: 218 YFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPS 277
Y E E R+ ++V PL I KGT +L + +H D + P
Sbjct: 402 YTEATIMEVQRL-TVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPE 460
Query: 278 KFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNTP 337
F P RF IPFG G R C+G + AK++ + V + F F L +++
Sbjct: 461 DFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSK 520
Query: 338 RNL 340
+ L
Sbjct: 521 KPL 523
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 83.8 bits (198), Expect = 8e-16
Identities = 47/175 (26%), Positives = 88/175 (50%), Gaps = 7/175 (4%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
+AG +T++ T+T+ LY L+ +P+IQ+ + E+ G+ + ++ ++ + E
Sbjct: 333 MAGVDTTSNTLTWALYHLSKDPEIQEALHEEV-VGVVPAGQVPQHKDFAHMPLLKAVLKE 391
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF- 284
TLR+Y +V R I+ +I + K T +F + D + P F P R+
Sbjct: 392 TLRLYPVVPTNSRI--IEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 449
Query: 285 ---SPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNT 336
PA +HP +PFG G R C+G R A+++ ++ + ++ K++ LA T
Sbjct: 450 RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPET 504
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 83.8 bits (198), Expect = 8e-16
Identities = 47/175 (26%), Positives = 88/175 (50%), Gaps = 7/175 (4%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
+AG +T++ T+T+ LY L+ +P+IQ+ + E+ G+ + ++ ++ + E
Sbjct: 334 MAGVDTTSNTLTWALYHLSKDPEIQEALHEEV-VGVVPAGQVPQHKDFAHMPLLKAVLKE 392
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF- 284
TLR+Y +V R I+ +I + K T +F + D + P F P R+
Sbjct: 393 TLRLYPVVPTNSRI--IEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 450
Query: 285 ---SPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNT 336
PA +HP +PFG G R C+G R A+++ ++ + ++ K++ LA T
Sbjct: 451 RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPET 505
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 83.8 bits (198), Expect = 8e-16
Identities = 47/175 (26%), Positives = 88/175 (50%), Gaps = 7/175 (4%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
+AG +T++ T+T+ LY L+ +P+IQ+ + E+ G+ + ++ ++ + E
Sbjct: 334 MAGVDTTSNTLTWALYHLSKDPEIQEALHEEV-VGVVPAGQVPQHKDFAHMPLLKAVLKE 392
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF- 284
TLR+Y +V R I+ +I + K T +F + D + P F P R+
Sbjct: 393 TLRLYPVVPTNSRI--IEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 450
Query: 285 ---SPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNT 336
PA +HP +PFG G R C+G R A+++ ++ + ++ K++ LA T
Sbjct: 451 RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPET 505
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 83.8 bits (198), Expect = 8e-16
Identities = 47/175 (26%), Positives = 88/175 (50%), Gaps = 7/175 (4%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
+AG +T++ T+T+ LY L+ +P+IQ+ + E+ G+ + ++ ++ + E
Sbjct: 334 MAGVDTTSNTLTWALYHLSKDPEIQEALHEEV-VGVVPAGQVPQHKDFAHMPLLKAVLKE 392
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF- 284
TLR+Y +V R I+ +I + K T +F + D + P F P R+
Sbjct: 393 TLRLYPVVPTNSRI--IEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 450
Query: 285 ---SPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNT 336
PA +HP +PFG G R C+G R A+++ ++ + ++ K++ LA T
Sbjct: 451 RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPET 505
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 83.8 bits (198), Expect = 8e-16
Identities = 76/310 (24%), Positives = 136/310 (43%), Gaps = 21/310 (6%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGFV 98
I++ FG D D K+ L L + TA +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYED--KEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFK 239
Query: 99 S-RFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 ELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ + AG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYYP 274
+ Y E +E R ++ P+ +++ D + KGT V F LG + D +++
Sbjct: 349 MPYTEAVIHEIQRFGDML-PMGLAHRVNKDTKFRDFFLPKGTEV-FPMLGSVLRDPRFFS 406
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
NP F+P+ F + A +PF G R C G A+++ + + FRF+ +
Sbjct: 407 NPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFK-SP 465
Query: 335 NTPRNLDIDP 344
+P+++D+ P
Sbjct: 466 QSPKDIDVSP 475
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 83.8 bits (198), Expect = 8e-16
Identities = 76/310 (24%), Positives = 136/310 (43%), Gaps = 21/310 (6%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGFV 98
I++ FG D D K+ L L + TA +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYED--KEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFK 239
Query: 99 S-RFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 ELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ + AG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYYP 274
+ Y E +E R ++ P+ +++ D + KGT V F LG + D +++
Sbjct: 349 MPYTEAVIHEIQRFGDML-PMGLAHRVNKDTKFRDFFLPKGTEV-FPMLGSVLRDPRFFS 406
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
NP F+P+ F + A +PF G R C G A+++ + + FRF+ +
Sbjct: 407 NPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFK-SP 465
Query: 335 NTPRNLDIDP 344
+P+++D+ P
Sbjct: 466 QSPKDIDVSP 475
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 83.8 bits (198), Expect = 8e-16
Identities = 76/310 (24%), Positives = 136/310 (43%), Gaps = 21/310 (6%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGFV 98
I++ FG D D K+ L L + TA +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYED--KEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFK 239
Query: 99 S-RFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 ELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ + AG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYYP 274
+ Y E +E R ++ P+ +++ D + KGT V F LG + D +++
Sbjct: 349 MPYTEAVIHEIQRFGDML-PMGLAHRVNKDTKFRDFFLPKGTEV-FPMLGSVLRDPRFFS 406
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
NP F+P+ F + A +PF G R C G A+++ + + FRF+ +
Sbjct: 407 NPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFK-SP 465
Query: 335 NTPRNLDIDP 344
+P+++D+ P
Sbjct: 466 QSPKDIDVSP 475
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 83.8 bits (198), Expect = 8e-16
Identities = 76/310 (24%), Positives = 136/310 (43%), Gaps = 21/310 (6%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGFV 98
I++ FG D D K+ L L + TA +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYED--KEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFK 239
Query: 99 S-RFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 ELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ + AG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYYP 274
+ Y E +E R ++ P+ +++ D + KGT V F LG + D +++
Sbjct: 349 MPYTEAVIHEIQRFGDML-PMGLAHRVNKDTKFRDFFLPKGTEV-FPMLGSVLRDPRFFS 406
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
NP F+P+ F + A +PF G R C G A+++ + + FRF+ +
Sbjct: 407 NPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFK-SP 465
Query: 335 NTPRNLDIDP 344
+P+++D+ P
Sbjct: 466 QSPKDIDVSP 475
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 83.8 bits (198), Expect = 8e-16
Identities = 76/310 (24%), Positives = 136/310 (43%), Gaps = 21/310 (6%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGFV 98
I++ FG D D K+ L L + TA +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYED--KEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFK 239
Query: 99 S-RFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 ELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ + AG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYYP 274
+ Y E +E R ++ P+ +++ D + KGT V F LG + D +++
Sbjct: 349 MPYTEAVIHEIQRFGDML-PMGLAHRVNKDTKFRDFFLPKGTEV-FPMLGSVLRDPRFFS 406
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
NP F+P+ F + A +PF G R C G A+++ + + FRF+ +
Sbjct: 407 NPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFK-SP 465
Query: 335 NTPRNLDIDP 344
+P+++D+ P
Sbjct: 466 QSPKDIDVSP 475
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 83.4 bits (197), Expect = 1e-15
Identities = 76/310 (24%), Positives = 136/310 (43%), Gaps = 21/310 (6%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGFV 98
I++ FG D D K+ L L + TA +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYED--KEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFK 239
Query: 99 S-RFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 ELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ + AG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPELEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYYP 274
+ Y E +E R ++ P+ +++ D + KGT V F LG + D +++
Sbjct: 349 MPYTEAVIHEIQRFGDML-PMGLAHRVNKDTKFRDFFLPKGTEV-FPMLGSVLRDPRFFS 406
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
NP F+P+ F + A +PF G R C G A+++ + + FRF+ +
Sbjct: 407 NPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFK-SP 465
Query: 335 NTPRNLDIDP 344
+P+++D+ P
Sbjct: 466 QSPKDIDVSP 475
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 83.4 bits (197), Expect = 1e-15
Identities = 48/175 (27%), Positives = 87/175 (49%), Gaps = 7/175 (4%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
+AG +T++ T+T+ LY L+ +P+IQ K + E G+ + ++ ++ + E
Sbjct: 334 MAGVDTTSNTLTWALYHLSKDPEIQ-KALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKE 392
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERF- 284
TLR+Y +V R I+ +I + K T +F + D + P F P R+
Sbjct: 393 TLRLYPVVPTNSRI--IEKEIEVDGFLFPKNTQFVFCHYEVSRDPTAFSEPESFQPHRWL 450
Query: 285 ---SPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAKNT 336
PA +HP +PFG G R C+G R A+++ ++ + ++ K++ LA T
Sbjct: 451 RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPET 505
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 83.0 bits (196), Expect = 1e-15
Identities = 60/251 (23%), Positives = 113/251 (45%), Gaps = 5/251 (1%)
Query: 94 FPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELT 153
FPG ++ K+++ T+ + + + +D+ R D K E E T
Sbjct: 106 FPGSHNKLLKNLL-TLKSYVLERIKEHQESLDMNNP-RDFIDCFLIKMEQEKHNQQSEFT 163
Query: 154 DELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEML 213
E + A + AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 164 VESLIATVTDMFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDR- 222
Query: 214 QNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYY 273
++ Y + +E R ++ P + + + +I KGTT+L S + HD K +
Sbjct: 223 SHMPYTDAVVHEVQRYIDLI-PTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEF 281
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
PNP FDP F + + +PF G R C+G A+++ + + + F + +
Sbjct: 282 PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLK-S 340
Query: 334 KNTPRNLDIDP 344
P++LD P
Sbjct: 341 LIDPKDLDTTP 351
>BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family
26, subfamily B, polypeptide 1 protein.
Length = 512
Score = 83.0 bits (196), Expect = 1e-15
Identities = 57/201 (28%), Positives = 98/201 (48%), Gaps = 10/201 (4%)
Query: 146 KEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEID-QGLKES 204
KE+ E+T + ++ A Y T+A+ T ++ QL +P + +K+ E+ G+ S
Sbjct: 275 KEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHS 334
Query: 205 -----KGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTV 259
+G + + L L Y + E +R+++ + R +++ I KG +V
Sbjct: 335 GGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQI--PKGWSV 392
Query: 260 LFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH-IPFGTGPRNCIGMRFAKIQSR 318
++S H + + + FDP+RFS A + H +PFG G R C+G AK+ +
Sbjct: 393 MYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLK 452
Query: 319 VCMVKMFSKFRFELAKNT-PR 338
V V++ S RFELA T PR
Sbjct: 453 VLAVELASTSRFELATRTFPR 473
>BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family
26, subfamily B, polypeptide 1 protein.
Length = 512
Score = 83.0 bits (196), Expect = 1e-15
Identities = 57/201 (28%), Positives = 98/201 (48%), Gaps = 10/201 (4%)
Query: 146 KEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEID-QGLKES 204
KE+ E+T + ++ A Y T+A+ T ++ QL +P + +K+ E+ G+ S
Sbjct: 275 KEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHS 334
Query: 205 -----KGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTV 259
+G + + L L Y + E +R+++ + R +++ I KG +V
Sbjct: 335 GGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQI--PKGWSV 392
Query: 260 LFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH-IPFGTGPRNCIGMRFAKIQSR 318
++S H + + + FDP+RFS A + H +PFG G R C+G AK+ +
Sbjct: 393 MYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLK 452
Query: 319 VCMVKMFSKFRFELAKNT-PR 338
V V++ S RFELA T PR
Sbjct: 453 VLAVELASTSRFELATRTFPR 473
>AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoid
metabolizing protein P450RAI-2 protein.
Length = 512
Score = 83.0 bits (196), Expect = 1e-15
Identities = 57/201 (28%), Positives = 98/201 (48%), Gaps = 10/201 (4%)
Query: 146 KEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEID-QGLKES 204
KE+ E+T + ++ A Y T+A+ T ++ QL +P + +K+ E+ G+ S
Sbjct: 275 KEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHS 334
Query: 205 -----KGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTV 259
+G + + L L Y + E +R+++ + R +++ I KG +V
Sbjct: 335 GGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQI--PKGWSV 392
Query: 260 LFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH-IPFGTGPRNCIGMRFAKIQSR 318
++S H + + + FDP+RFS A + H +PFG G R C+G AK+ +
Sbjct: 393 MYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLK 452
Query: 319 VCMVKMFSKFRFELAKNT-PR 338
V V++ S RFELA T PR
Sbjct: 453 VLAVELASTSRFELATRTFPR 473
>AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein.
Length = 512
Score = 83.0 bits (196), Expect = 1e-15
Identities = 57/201 (28%), Positives = 98/201 (48%), Gaps = 10/201 (4%)
Query: 146 KEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEID-QGLKES 204
KE+ E+T + ++ A Y T+A+ T ++ QL +P + +K+ E+ G+ S
Sbjct: 275 KEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHS 334
Query: 205 -----KGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTV 259
+G + + L L Y + E +R+++ + R +++ I KG +V
Sbjct: 335 GGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQI--PKGWSV 392
Query: 260 LFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH-IPFGTGPRNCIGMRFAKIQSR 318
++S H + + + FDP+RFS A + H +PFG G R C+G AK+ +
Sbjct: 393 MYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLK 452
Query: 319 VCMVKMFSKFRFELAKNT-PR 338
V V++ S RFELA T PR
Sbjct: 453 VLAVELASTSRFELATRTFPR 473
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 82.6 bits (195), Expect = 2e-15
Identities = 78/309 (25%), Positives = 135/309 (43%), Gaps = 23/309 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYED--KEFLSLLSMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFK 239
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLQGLEDFIAKKVEHNQRTLDPNSPQDFIDSFLIHMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +IAG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRTK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V F LG + D ++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-FPMLGSVLRDPSFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF G R C G A+++ + + FR + +
Sbjct: 406 SNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDI 342
+P+++D+
Sbjct: 465 SQSPKDIDV 473
>X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C
protein.
Length = 356
Score = 82.2 bits (194), Expect = 3e-15
Identities = 64/251 (25%), Positives = 110/251 (43%), Gaps = 5/251 (1%)
Query: 94 FPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELT 153
FPG ++ K+V T R K + +D + R D K E E T
Sbjct: 92 FPGTHNKVLKNVALTRSYIRE-KVKEHQASLD-VNNPRDFIDCFLIKMEQEKDNQKSEFT 149
Query: 154 DELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEML 213
E + A AG ET++TT+ + L L +P++ KV EI++ + ++ +
Sbjct: 150 IENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDR- 208
Query: 214 QNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYY 273
++ Y + +E R ++ P + I + +I KGTT+L S + HD K +
Sbjct: 209 GHMPYTDAVVHEVQRYIDLI-PTSLPHAVTCDIKFRNYLIPKGTTILTSLTSVLHDNKEF 267
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
PNP FDP F + + +PF G R C+G A+++ + + + F + +
Sbjct: 268 PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLK-S 326
Query: 334 KNTPRNLDIDP 344
P++LD P
Sbjct: 327 LIDPKDLDTTP 337
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 82.2 bits (194), Expect = 3e-15
Identities = 78/311 (25%), Positives = 135/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGFV 98
I++ FG D D K+ L L + T+ +L M+ ++K L F
Sbjct: 182 ISSIVFGDRFDYED--KEFLSLLSMMLGIFQFTSTSTGQLYEMFSSLMKHLPGPQQQAFK 239
Query: 99 SRF-FKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLLGLEDFIAKKVEHNQRTLDPNSPQDFIDSFLIHMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +IAG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRTK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KGT V F LG + D +++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEV-FPMLGSVLRDLRFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF RNC G A+++ + + FR + +
Sbjct: 406 SNPRDFNPQHFLGEKGQFKKRDAFVPFSIRKRNCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 465 SQSPKDIDVSP 475
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 82.2 bits (194), Expect = 3e-15
Identities = 78/311 (25%), Positives = 136/311 (43%), Gaps = 23/311 (7%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGF- 97
I++ FG D D K+ L L + T+ +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYKD--KEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQ 239
Query: 98 VSRFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ + +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 LLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ +IAG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLMMSTLNLFIAGTETVSTTLHYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIEKGTTVLFSPLG-IHHDEKYY 273
+ Y E +E R ++ L R K D K D + KG V F LG + D +++
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGIEV-FPMLGSVLRDLRFF 405
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELA 333
NP F+P+ F + A +PF RNC G A+++ + + FR + +
Sbjct: 406 SNPRDFNPQHFLGEKGQFKKRDAFVPFSIRKRNCFGEGLARMELFLFFTTVMQNFRLK-S 464
Query: 334 KNTPRNLDIDP 344
+P+++D+ P
Sbjct: 465 SQSPKDIDVSP 475
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 82.2 bits (194), Expect = 3e-15
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE-SKGEVT 209
EL + I +AG +T + T+++ LY+L+ +P++Q + +EI L S +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
+L L + E LR+Y +V R D + D +I K T V D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGD--YIIPKNTLVTLCHYATSRD 418
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P P+ F P R+ + HP A +PFG G R+C+G R A+++ ++ + ++ + F
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFE 477
Query: 330 FE 331
+
Sbjct: 478 VQ 479
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 82.2 bits (194), Expect = 3e-15
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE-SKGEVT 209
EL + I +AG +T + T+++ LY+L+ +P++Q + +EI L S +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
+L L + E LR+Y +V R D + D +I K T V D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGD--YIIPKNTLVTLCHYATSRD 418
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P P+ F P R+ + HP A +PFG G R+C+G R A+++ ++ + ++ + F
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFE 477
Query: 330 FE 331
+
Sbjct: 478 VQ 479
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 82.2 bits (194), Expect = 3e-15
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE-SKGEVT 209
EL + I +AG +T + T+++ LY+L+ +P++Q + +EI L S +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
+L L + E LR+Y +V R D + D +I K T V D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGD--YIIPKNTLVTLCHYATSRD 418
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P P+ F P R+ + HP A +PFG G R+C+G R A+++ ++ + ++ + F
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFE 477
Query: 330 FE 331
+
Sbjct: 478 VQ 479
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 82.2 bits (194), Expect = 3e-15
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE-SKGEVT 209
EL + I +AG +T + T+++ LY+L+ +P++Q + +EI L S +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
+L L + E LR+Y +V R D + D +I K T V D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGD--YIIPKNTLVTLCHYATSRD 418
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P P+ F P R+ + HP A +PFG G R+C+G R A+++ ++ + ++ + F
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFE 477
Query: 330 FE 331
+
Sbjct: 478 VQ 479
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 82.2 bits (194), Expect = 3e-15
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE-SKGEVT 209
EL + I +AG +T + T+++ LY+L+ +P++Q + +EI L S +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
+L L + E LR+Y +V R D + D +I K T V D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGD--YIIPKNTLVTLCHYATSRD 418
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P P+ F P R+ + HP A +PFG G R+C+G R A+++ ++ + ++ + F
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFE 477
Query: 330 FE 331
+
Sbjct: 478 VQ 479
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 82.2 bits (194), Expect = 3e-15
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE-SKGEVT 209
EL + I +AG +T + T+++ LY+L+ +P++Q + +EI L S +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
+L L + E LR+Y +V R D + D +I K T V D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGD--YIIPKNTLVTLCHYATSRD 418
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P P+ F P R+ + HP A +PFG G R+C+G R A+++ ++ + ++ + F
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFE 477
Query: 330 FE 331
+
Sbjct: 478 VQ 479
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 82.2 bits (194), Expect = 3e-15
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE-SKGEVT 209
EL + I +AG +T + T+++ LY+L+ +P++Q + +EI L S +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
+L L + E LR+Y +V R D + D +I K T V D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGD--YIIPKNTLVTLCHYATSRD 418
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P P+ F P R+ + HP A +PFG G R+C+G R A+++ ++ + ++ + F
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFE 477
Query: 330 FE 331
+
Sbjct: 478 VQ 479
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 82.2 bits (194), Expect = 3e-15
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE-SKGEVT 209
EL + I +AG +T + T+++ LY+L+ +P++Q + +EI L S +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
+L L + E LR+Y +V R D + D +I K T V D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGD--YIIPKNTLVTLCHYATSRD 418
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P P+ F P R+ + HP A +PFG G R+C+G R A+++ ++ + ++ + F
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFE 477
Query: 330 FE 331
+
Sbjct: 478 VQ 479
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 82.2 bits (194), Expect = 3e-15
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE-SKGEVT 209
EL + I +AG +T + T+++ LY+L+ +P++Q + +EI L S +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 210 YEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHD 269
+L L + E LR+Y +V R D + D +I K T V D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGD--YIIPKNTLVTLCHYATSRD 418
Query: 270 EKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFR 329
+P P+ F P R+ + HP A +PFG G R+C+G R A+++ ++ + ++ + F
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFE 477
Query: 330 FE 331
+
Sbjct: 478 VQ 479
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 81.8 bits (193), Expect = 3e-15
Identities = 64/254 (25%), Positives = 113/254 (44%), Gaps = 11/254 (4%)
Query: 94 FPGFVSRFFKDVV---KTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
FPG ++ K++ I+E K + + MD I R D K E +
Sbjct: 226 FPGTHNKLLKNLAFMESDILE----KVKEHQESMD-INNPRDFIDCFLIKMEKEKQNQQS 280
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
E T E + A AG ET++TT+ + L L +P++ KV EI++ + ++
Sbjct: 281 EFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ 340
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ ++ Y + +E R ++ P + + + +I KGTT+L S + HD
Sbjct: 341 DR-GHMPYTDAVVHEVQRYIDLI-PTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDN 398
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
K +PNP FDP F + + +PF G R C+G A+++ + + + F
Sbjct: 399 KEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
Query: 331 ELAKNTPRNLDIDP 344
+ + P++LD P
Sbjct: 459 K-SLIDPKDLDTTP 471
>AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 421
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/126 (38%), Positives = 63/126 (50%), Gaps = 5/126 (3%)
Query: 213 LQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKY 272
L + Y E LR+Y V + R PD + KG VL S G+HH+ K
Sbjct: 268 LDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPKV 326
Query: 273 YPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFEL 332
+PN FDP RF+P SA+H A +PF G RNCIG +FA Q +V + + RFEL
Sbjct: 327 WPNLEVFDPSRFAPG--SAQHSHAFLPFSGGSRNCIGKQFAMNQLKV--ARALTLLRFEL 382
Query: 333 AKNTPR 338
+ R
Sbjct: 383 LPDPTR 388
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 81.4 bits (192), Expect = 5e-15
Identities = 64/254 (25%), Positives = 113/254 (44%), Gaps = 11/254 (4%)
Query: 94 FPGFVSRFFKDVV---KTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
FPG ++ K++ I+E K + + MD I R D K E +
Sbjct: 204 FPGTHNKLLKNLAFMESDILE----KVKEHQESMD-INNPRDFIDCFLIKMEKEKQNQQS 258
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
E T E + A AG ET++TT+ + L L +P++ KV EI++ + ++
Sbjct: 259 EFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQ 318
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ ++ Y + +E R ++ P + + + +I KGTT+L S + HD
Sbjct: 319 DR-GHMPYTDAVVHEVQRYIDLI-PTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDN 376
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
K +PNP FDP F + + +PF G R C+G A+++ + + + F
Sbjct: 377 KEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 436
Query: 331 ELAKNTPRNLDIDP 344
+ + P++LD P
Sbjct: 437 K-SLIDPKDLDTTP 449
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 81.4 bits (192), Expect = 5e-15
Identities = 64/254 (25%), Positives = 113/254 (44%), Gaps = 11/254 (4%)
Query: 94 FPGFVSRFFKDVV---KTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
FPG ++ K++ I+E K + + MD I R D K E +
Sbjct: 226 FPGTHNKLLKNLAFMESDILE----KVKEHQESMD-INNPRDFIDCFLIKMEKEKQNQQS 280
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
E T E + A AG ET++TT+ + L L +P++ KV EI++ + ++
Sbjct: 281 EFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQ 340
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ ++ Y + +E R ++ P + + + +I KGTT+L S + HD
Sbjct: 341 DR-GHMPYTDAVVHEVQRYIDLI-PTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDN 398
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
K +PNP FDP F + + +PF G R C+G A+++ + + + F
Sbjct: 399 KEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
Query: 331 ELAKNTPRNLDIDP 344
+ + P++LD P
Sbjct: 459 K-SLIDPKDLDTTP 471
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 81.4 bits (192), Expect = 5e-15
Identities = 64/254 (25%), Positives = 113/254 (44%), Gaps = 11/254 (4%)
Query: 94 FPGFVSRFFKDVV---KTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
FPG ++ K++ I+E K + + MD I R D K E +
Sbjct: 226 FPGTHNKLLKNLAFMESDILE----KVKEHQESMD-INNPRDFIDCFLIKMEKEKQNQQS 280
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
E T E + A AG ET++TT+ + L L +P++ KV EI++ + ++
Sbjct: 281 EFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQ 340
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ ++ Y + +E R ++ P + + + +I KGTT+L S + HD
Sbjct: 341 DR-GHMPYTDAVVHEVQRYIDLI-PTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDN 398
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
K +PNP FDP F + + +PF G R C+G A+++ + + + F
Sbjct: 399 KEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
Query: 331 ELAKNTPRNLDIDP 344
+ + P++LD P
Sbjct: 459 K-SLIDPKDLDTTP 471
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 81.4 bits (192), Expect = 5e-15
Identities = 64/254 (25%), Positives = 113/254 (44%), Gaps = 11/254 (4%)
Query: 94 FPGFVSRFFKDVV---KTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSI 150
FPG ++ K++ I+E K + + MD I R D K E +
Sbjct: 226 FPGTHNKLLKNLAFMESDILE----KVKEHQESMD-INNPRDFIDCFLIKMEKEKQNQQS 280
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
E T E + A AG ET++TT+ + L L +P++ KV EI++ + ++
Sbjct: 281 EFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQ 340
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ ++ Y + +E R ++ P + + + +I KGTT+L S + HD
Sbjct: 341 DR-GHMPYTDAVVHEVQRYIDLI-PTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDN 398
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
K +PNP FDP F + + +PF G R C+G A+++ + + + F
Sbjct: 399 KEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
Query: 331 ELAKNTPRNLDIDP 344
+ + P++LD P
Sbjct: 459 K-SLIDPKDLDTTP 471
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 80.6 bits (190), Expect = 8e-15
Identities = 75/310 (24%), Positives = 133/310 (42%), Gaps = 21/310 (6%)
Query: 40 IAACAFGLDIDTTDPNKDQLKTLEE-IDRLSLTANFAFELDMMYPGVLKKLNSTLFPGFV 98
I++ FG D D K+ L L + R T +L M+ V+K L F
Sbjct: 182 ISSIVFGDRFDYED--KEFLSLLRMMLGRFQFTGTSTGQLYEMFSSVMKHLPGPQQQAFK 239
Query: 99 S-RFFKDVVKTIIE--QRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELTDE 155
+ +D + +E QR P DF+D L Q E+K + E +
Sbjct: 240 ELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ----------EEEKNPNTEFYLK 289
Query: 156 LIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQN 215
+ + AG ET +TT+ + L +P+++ KV EID+ + +++ + +E
Sbjct: 290 NLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNR-QPKFEDRAK 348
Query: 216 LTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIH-HDEKYYP 274
+ Y E +E R ++ P+ +++ D + KGT V F LG D +++
Sbjct: 349 MPYTEAVIHEIQRFGDML-PMGLAHRVNKDTKFRDFFLPKGTEV-FPMLGSELRDPRFFS 406
Query: 275 NPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFELAK 334
NP P+ F + A +PF G R C G A+++ + + FRF+ +
Sbjct: 407 NPQDCSPQHFLDEKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFK-SP 465
Query: 335 NTPRNLDIDP 344
+P+++D+ P
Sbjct: 466 QSPKDIDVSP 475
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 79.8 bits (188), Expect = 1e-14
Identities = 53/214 (24%), Positives = 98/214 (45%), Gaps = 3/214 (1%)
Query: 131 RQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQ 190
R D K E E T E + A + AG ET++TT+ + L L P++
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 191 DKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTD 250
KV EI+ + ++ + ++ Y + +E R ++ P + + +
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDR-SHMPYTDAVVHEIQRYIDLL-PTNLPHAVTCDVKFKN 378
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGM 310
+I KGTT++ S + H++K +PNP FDP F + + + +PF G R C+G
Sbjct: 379 YLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGE 438
Query: 311 RFAKIQSRVCMVKMFSKFRFELAKNTPRNLDIDP 344
A+++ + + + F + +K P+++DI P
Sbjct: 439 GLARMELFLFLTTILQNFNLK-SKVDPKDIDITP 471
>X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein.
Length = 521
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/182 (26%), Positives = 94/182 (51%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+++ E I+A G +T++ T+ + LY++A N +QD + AE+ +++G++
Sbjct: 310 KMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMA- 368
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
MLQ + + + ETLR++ I LQR D + D +I T V + + +
Sbjct: 369 TMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVL--RDYMIPAKTLVQVAIYALGREP 426
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
++ +P FDP R+ + + + ++ FG G R C+G R A+++ + ++ M FR
Sbjct: 427 TFFFDPENFDPTRWLSKDKNITY-FRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRV 485
Query: 331 EL 332
E+
Sbjct: 486 EI 487
>M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc
protein.
Length = 239
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/182 (26%), Positives = 94/182 (51%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+++ E I+A G +T++ T+ + LY++A N +QD + AE+ +++G++
Sbjct: 28 KMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMA- 86
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
MLQ + + + ETLR++ I LQR D + D +I T V + + +
Sbjct: 87 TMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVL--RDYMIPAKTLVQVAIYALGREP 144
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
++ +P FDP R+ + + + ++ FG G R C+G R A+++ + ++ M FR
Sbjct: 145 TFFFDPENFDPTRWLSKDKNITY-FRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRV 203
Query: 331 EL 332
E+
Sbjct: 204 EI 205
>M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein.
Length = 521
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/182 (26%), Positives = 94/182 (51%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+++ E I+A G +T++ T+ + LY++A N +QD + AE+ +++G++
Sbjct: 310 KMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMA- 368
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
MLQ + + + ETLR++ I LQR D + D +I T V + + +
Sbjct: 369 TMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVL--RDYMIPAKTLVQVAIYALGREP 426
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
++ +P FDP R+ + + + ++ FG G R C+G R A+++ + ++ M FR
Sbjct: 427 TFFFDPENFDPTRWLSKDKNITY-FRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRV 485
Query: 331 EL 332
E+
Sbjct: 486 EI 487
>L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 217
Score = 79.0 bits (186), Expect = 2e-14
Identities = 51/201 (25%), Positives = 93/201 (46%), Gaps = 3/201 (1%)
Query: 144 EDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKE 203
E + E T E + A AG ET++TT+ + L L +P++ KV EI++ +
Sbjct: 1 EKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGR 60
Query: 204 SKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSP 263
++ + ++ Y + +E R ++ P + + + +I KGTT+L S
Sbjct: 61 NRSPCMQDR-GHMPYTDAVVHEVQRYIDLI-PTSLPHAVTCDVKFRNYLIPKGTTILTSL 118
Query: 264 LGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVK 323
+ HD K +PNP FDP F + + +PF G R C+G A+++ + +
Sbjct: 119 TSVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTF 178
Query: 324 MFSKFRFELAKNTPRNLDIDP 344
+ F + + P++LD P
Sbjct: 179 ILQNFNLK-SLIDPKDLDTTP 198
>BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family
11, subfamily A, polypeptide 1 protein.
Length = 521
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/182 (26%), Positives = 94/182 (51%), Gaps = 4/182 (2%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+++ E I+A G +T++ T+ + LY++A N +QD + AE+ +++G++
Sbjct: 310 KMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMA- 368
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
MLQ + + + ETLR++ I LQR D + D +I T V + + +
Sbjct: 369 TMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVL--RDYMIPAKTLVQVAIYALGREP 426
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRF 330
++ +P FDP R+ + + + ++ FG G R C+G R A+++ + ++ M FR
Sbjct: 427 TFFFDPENFDPTRWLSKDKNITY-FRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRV 485
Query: 331 EL 332
E+
Sbjct: 486 EI 487
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 78.6 bits (185), Expect = 3e-14
Identities = 50/163 (30%), Positives = 81/163 (49%), Gaps = 2/163 (1%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
IAG ET+ + + + +AL P+IQ +V EID + G+ +++ + Y E +E
Sbjct: 309 IAGTETTTNVLRWAILFMALYPNIQGQVQKEIDL-IMGPNGKPSWDDKCKMPYTEAVLHE 367
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFS 285
LR +IV PL I KGTTV+ + +H DEKY+ +P F PERF
Sbjct: 368 VLRFCNIV-PLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFL 426
Query: 286 PANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
++ A +PF G R+C+G A+++ + + +F
Sbjct: 427 DSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRF 469
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 78.6 bits (185), Expect = 3e-14
Identities = 50/163 (30%), Positives = 81/163 (49%), Gaps = 2/163 (1%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
IAG ET+ + + + +AL P+IQ +V EID + G+ +++ + Y E +E
Sbjct: 309 IAGTETTTNVLRWAILFMALYPNIQGQVQKEIDL-IMGPNGKPSWDDKCKMPYTEAVLHE 367
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFS 285
LR +IV PL I KGTTV+ + +H DEKY+ +P F PERF
Sbjct: 368 VLRFCNIV-PLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFL 426
Query: 286 PANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
++ A +PF G R+C+G A+++ + + +F
Sbjct: 427 DSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRF 469
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 78.6 bits (185), Expect = 3e-14
Identities = 50/163 (30%), Positives = 81/163 (49%), Gaps = 2/163 (1%)
Query: 166 IAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNE 225
IAG ET+ + + + +AL P+IQ +V EID + G+ +++ + Y E +E
Sbjct: 309 IAGTETTTNVLRWAILFMALYPNIQGQVQKEIDL-IMGPNGKPSWDDKCKMPYTEAVLHE 367
Query: 226 TLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFS 285
LR +IV PL I KGTTV+ + +H DEKY+ +P F PERF
Sbjct: 368 VLRFCNIV-PLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFL 426
Query: 286 PANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
++ A +PF G R+C+G A+++ + + +F
Sbjct: 427 DSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRF 469
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 78.2 bits (184), Expect = 4e-14
Identities = 52/214 (24%), Positives = 98/214 (45%), Gaps = 3/214 (1%)
Query: 131 RQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQ 190
R D K E E T E + A + AG ET++TT+ + L L P++
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 191 DKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTD 250
KV EI+ + ++ + ++ Y + +E R ++ P + + +
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDR-SHMPYTDAVVHEIQRYIDLL-PTNLPHAVTCDVKFKN 378
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGM 310
+I KGTT++ S + H++K +PNP FDP F + + + +PF G R C+G
Sbjct: 379 YLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGE 438
Query: 311 RFAKIQSRVCMVKMFSKFRFELAKNTPRNLDIDP 344
A+++ + + + F + ++ P+++DI P
Sbjct: 439 GLARMELFLFLTTILQNFNLK-SQVDPKDIDITP 471
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 78.2 bits (184), Expect = 4e-14
Identities = 52/214 (24%), Positives = 98/214 (45%), Gaps = 3/214 (1%)
Query: 131 RQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQ 190
R D K E E T E + A + AG ET++TT+ + L L P++
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 191 DKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTD 250
KV EI+ + ++ + ++ Y + +E R ++ P + + +
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDR-SHMPYTDAVVHEIQRYIDLL-PTNLPHAVTCDVKFKN 378
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGM 310
+I KGTT++ S + H++K +PNP FDP F + + + +PF G R C+G
Sbjct: 379 YLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGE 438
Query: 311 RFAKIQSRVCMVKMFSKFRFELAKNTPRNLDIDP 344
A+++ + + + F + ++ P+++DI P
Sbjct: 439 GLARMELFLFLTTILQNFNLK-SQVDPKDIDITP 471
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 78.2 bits (184), Expect = 4e-14
Identities = 52/214 (24%), Positives = 98/214 (45%), Gaps = 3/214 (1%)
Query: 131 RQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQ 190
R D K E E T E + A + AG ET++TT+ + L L P++
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 191 DKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTD 250
KV EI+ + ++ + ++ Y + +E R ++ P + + +
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDR-SHMPYTDAVVHEIQRYIDLL-PTNLPHAVTCDVKFKN 378
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGM 310
+I KGTT++ S + H++K +PNP FDP F + + + +PF G R C+G
Sbjct: 379 YLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGE 438
Query: 311 RFAKIQSRVCMVKMFSKFRFELAKNTPRNLDIDP 344
A+++ + + + F + ++ P+++DI P
Sbjct: 439 GLARMELFLFLTTILQNFNLK-SQVDPKDIDITP 471
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 78.2 bits (184), Expect = 4e-14
Identities = 52/214 (24%), Positives = 98/214 (45%), Gaps = 3/214 (1%)
Query: 131 RQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQ 190
R D K E E T E + A + AG ET++TT+ + L L P++
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 191 DKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTD 250
KV EI+ + ++ + ++ Y + +E R ++ P + + +
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDR-SHMPYTDAVVHEIQRYIDLL-PTNLPHAVTCDVKFKN 378
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGM 310
+I KGTT++ S + H++K +PNP FDP F + + + +PF G R C+G
Sbjct: 379 YLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGE 438
Query: 311 RFAKIQSRVCMVKMFSKFRFELAKNTPRNLDIDP 344
A+++ + + + F + ++ P+++DI P
Sbjct: 439 GLARMELFLFLTTILQNFNLK-SQVDPKDIDITP 471
>BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family
51, subfamily A, polypeptide 1 protein.
Length = 509
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/181 (27%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
LTD+ + +AG TS+TT +M + LA + +Q K E E+ +TY+
Sbjct: 302 LTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYD 361
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L++L ++ ETLR+ V + R A+ + I G V SP +
Sbjct: 362 QLKDLNLLDRCIKETLRLRPPVMIMMRMARTPQTV--AGYTIPPGHQVCVSPTVNQRLKD 419
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+ F+P+R+ N ++ A++PFG G CIG FA +Q + M + F+
Sbjct: 420 SWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFD 479
Query: 332 L 332
L
Sbjct: 480 L 480
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 78.2 bits (184), Expect = 4e-14
Identities = 52/214 (24%), Positives = 98/214 (45%), Gaps = 3/214 (1%)
Query: 131 RQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQ 190
R D K E E T E + A + AG ET++TT+ + L L P++
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 191 DKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTD 250
KV EI+ + ++ + ++ Y + +E R ++ P + + +
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDR-SHMPYTDAVVHEIQRYIDLL-PTNLPHAVTCDVKFKN 378
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGM 310
+I KGTT++ S + H++K +PNP FDP F + + + +PF G R C+G
Sbjct: 379 YLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGE 438
Query: 311 RFAKIQSRVCMVKMFSKFRFELAKNTPRNLDIDP 344
A+++ + + + F + ++ P+++DI P
Sbjct: 439 GLARMELFLFLTTILQNFNLK-SQVDPKDIDITP 471
>U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha
demethylase protein.
Length = 503
Score = 77.8 bits (183), Expect = 6e-14
Identities = 49/181 (27%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
LTD+ + +AG TS+TT +M + LA + +Q K E E+ +TY+
Sbjct: 296 LTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYD 355
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L++L ++ ETLR+ + + R A+ + I G V SP +
Sbjct: 356 QLKDLNLLDRCIRETLRLRPPIMIMMRMARTPQTV--AGYTIPPGHQVCVSPTVNQRLKD 413
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+ F+P+R+ N ++ A++PFG G CIG FA +Q + M + F+
Sbjct: 414 SWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFD 473
Query: 332 L 332
L
Sbjct: 474 L 474
>U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase
cytochrome P450 protein.
Length = 509
Score = 77.8 bits (183), Expect = 6e-14
Identities = 49/181 (27%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
LTD+ + +AG TS+TT +M + LA + +Q K E E+ +TY+
Sbjct: 302 LTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYD 361
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L++L ++ ETLR+ + + R A+ + I G V SP +
Sbjct: 362 QLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTV--AGYTIPPGHQVCVSPTVNQRLKD 419
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+ F+P+R+ N ++ A++PFG G CIG FA +Q + M + F+
Sbjct: 420 SWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFD 479
Query: 332 L 332
L
Sbjct: 480 L 480
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 77.8 bits (183), Expect = 6e-14
Identities = 64/259 (24%), Positives = 118/259 (45%), Gaps = 17/259 (6%)
Query: 73 NFAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQ 132
NF +D +PG K+ + + ++ VK Q + + DFMD L +
Sbjct: 218 NFPLLIDC-FPGTHNKVLKNV--ALTRSYIREKVKE--HQASLDVNNPRDFMDCFLIKME 272
Query: 133 LGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDK 192
+++++ E++IE L+ A +F +AG ET++TT+ + L L +P++ K
Sbjct: 273 ------QEKDNQKSEFNIE---NLVGTVADLF-VAGTETTSTTLRYGLLLLLKHPEVTAK 322
Query: 193 VIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIV 252
V EID + + + ++ Y + +E R YS + P + + +
Sbjct: 323 VQEEIDHVIGRHRSPCMQDR-SHMPYTDAVVHEIQR-YSDLVPTGVPHAVTTDTKFRNYL 380
Query: 253 IEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRF 312
I KGTT++ + HD+K +PNP+ FDP F N + + +PF G R C G
Sbjct: 381 IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGL 440
Query: 313 AKIQSRVCMVKMFSKFRFE 331
A+++ + + + F +
Sbjct: 441 ARMELFLFLTTILQNFNLK 459
>D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase
protein.
Length = 509
Score = 77.8 bits (183), Expect = 6e-14
Identities = 49/181 (27%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
LTD+ + +AG TS+TT +M + LA + +Q K E E+ +TY+
Sbjct: 302 LTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYD 361
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L++L ++ ETLR+ + + R A+ + I G V SP +
Sbjct: 362 QLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTV--AGYTIPPGHQVCVSPTVNQRLKD 419
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+ F+P+R+ N ++ A++PFG G CIG FA +Q + M + F+
Sbjct: 420 SWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFD 479
Query: 332 L 332
L
Sbjct: 480 L 480
>AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein.
Length = 509
Score = 77.8 bits (183), Expect = 6e-14
Identities = 49/181 (27%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Query: 152 LTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYE 211
LTD+ + +AG TS+TT +M + LA + +Q K E E+ +TY+
Sbjct: 302 LTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYD 361
Query: 212 MLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEK 271
L++L ++ ETLR+ + + R A+ + I G V SP +
Sbjct: 362 QLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTV--AGYTIPPGHQVCVSPTVNQRLKD 419
Query: 272 YYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
+ F+P+R+ N ++ A++PFG G CIG FA +Q + M + F+
Sbjct: 420 SWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFD 479
Query: 332 L 332
L
Sbjct: 480 L 480
>Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for
aromatase P-450. ).
Length = 503
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 290 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 404
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 405 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for
aromatase (estrogen synthetase). ).
Length = 503
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 290 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 404
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 405 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase
cytochrome P-450 gene, exon 10. ).
Length = 503
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 290 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 404
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 405 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase
protein.
Length = 419
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 206 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 263
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 264 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 320
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 321 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 374
>M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase
mRNA, complete cds. ).
Length = 503
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 290 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 404
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 405 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase
(Aro1) mRNA, complete cds. ).
Length = 419
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 206 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 263
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 264 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 320
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 321 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 374
>J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein.
Length = 503
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 290 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 404
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 405 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily
19 subfamily A polypeptide 1 protein.
Length = 503
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 290 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 404
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 405 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 290 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 404
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 405 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 290 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 404
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 405 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 77.4 bits (182), Expect = 7e-14
Identities = 48/178 (26%), Positives = 91/178 (51%), Gaps = 9/178 (5%)
Query: 151 ELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTY 210
+LT E + IA +T + ++ FML+ +A +P++++ +I EI + E ++
Sbjct: 290 DLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER--DIKI 347
Query: 211 EMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDE 270
+ +Q L E E++R +V+ + R A D I ++KGT ++ + +G H
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILN-IGRMHRL 404
Query: 271 KYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKF 328
+++P P++F E F+ N+ R+ PFG GPR C G A + + +V + +F
Sbjct: 405 EFFPKPNEFTLENFA-KNVPYRY---FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 76.6 bits (180), Expect = 1e-13
Identities = 59/238 (24%), Positives = 102/238 (42%), Gaps = 4/238 (1%)
Query: 94 FPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELT 153
FPG ++ K+V T R K + +D + R D K E E
Sbjct: 226 FPGTHNKVLKNVALTRSYIRE-KVKEHQASLD-VNNPRDFIDCFLIKMEQEKDNQKSEFN 283
Query: 154 DELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEML 213
E + ++AG ET++TT+ + L L +P++ KV EID + + +
Sbjct: 284 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR- 342
Query: 214 QNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYY 273
++ Y + +E R YS + P + + +I KGTT++ + HD+K +
Sbjct: 343 SHMPYTDAVVHEIQR-YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 401
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
PNP+ FDP F N + + +PF G R C G A+++ + + + F +
Sbjct: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 76.6 bits (180), Expect = 1e-13
Identities = 59/238 (24%), Positives = 102/238 (42%), Gaps = 4/238 (1%)
Query: 94 FPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELT 153
FPG ++ K+V T R K + +D + R D K E E
Sbjct: 198 FPGTHNKVLKNVALTRSYIRE-KVREHQASLD-VNNPRDFIDCFLIKMEQEKDNQKSEFN 255
Query: 154 DELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEML 213
E + ++AG ET++TT+ + L L +P++ KV EID + + +
Sbjct: 256 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR- 314
Query: 214 QNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYY 273
++ Y + +E R YS + P + + +I KGTT++ + HD+K +
Sbjct: 315 SHMPYTDAVVHEIQR-YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 373
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
PNP+ FDP F N + + +PF G R C G A+++ + + + F +
Sbjct: 374 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 431
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 76.6 bits (180), Expect = 1e-13
Identities = 52/215 (24%), Positives = 105/215 (48%), Gaps = 7/215 (3%)
Query: 130 LRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDI 189
LR L +++++ E+++E LI +F AG ET++TT+ + L L P++
Sbjct: 84 LRILSSPWIQEKHNQQSEFTVE---SLIATVTDMFG-AGTETTSTTLRYGLLLLLKYPEV 139
Query: 190 QDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDT 249
KV EI+ + ++ + ++ Y + +E R ++ P + +
Sbjct: 140 TAKVQEEIECVVGRNRSPCMQDR-SHMPYTDAVVHEIQRYIDLL-PTNLPHAVTCDVKFK 197
Query: 250 DIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIG 309
+ +I KGTT++ S + H++K +PNP FDP F + + + +PF G R C+G
Sbjct: 198 NYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMG 257
Query: 310 MRFAKIQSRVCMVKMFSKFRFELAKNTPRNLDIDP 344
A+++ + + + F + ++ P+++DI P
Sbjct: 258 EGLARMELFLFLTTILQNFNLK-SQVDPKDIDITP 291
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 76.6 bits (180), Expect = 1e-13
Identities = 52/215 (24%), Positives = 105/215 (48%), Gaps = 7/215 (3%)
Query: 130 LRQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDI 189
LR L +++++ E+++E LI +F AG ET++TT+ + L L P++
Sbjct: 205 LRILSSPWIQEKHNQQSEFTVE---SLIATVTDMFG-AGTETTSTTLRYGLLLLLKYPEV 260
Query: 190 QDKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDT 249
KV EI+ + ++ + ++ Y + +E R ++ P + +
Sbjct: 261 TAKVQEEIECVVGRNRSPCMQDR-SHMPYTDAVVHEIQRYIDLL-PTNLPHAVTCDVKFK 318
Query: 250 DIVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIG 309
+ +I KGTT++ S + H++K +PNP FDP F + + + +PF G R C+G
Sbjct: 319 NYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMG 378
Query: 310 MRFAKIQSRVCMVKMFSKFRFELAKNTPRNLDIDP 344
A+++ + + + F + ++ P+++DI P
Sbjct: 379 EGLARMELFLFLTTILQNFNLK-SQVDPKDIDITP 412
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 76.6 bits (180), Expect = 1e-13
Identities = 59/238 (24%), Positives = 102/238 (42%), Gaps = 4/238 (1%)
Query: 94 FPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELT 153
FPG ++ K+V T R K + +D + R D K E E
Sbjct: 226 FPGTHNKVLKNVALTRSYIRE-KVKEHQASLD-VNNPRDFIDCFLIKMEQEKDNQKSEFN 283
Query: 154 DELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEML 213
E + ++AG ET++TT+ + L L +P++ KV EID + + +
Sbjct: 284 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR- 342
Query: 214 QNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYY 273
++ Y + +E R YS + P + + +I KGTT++ + HD+K +
Sbjct: 343 SHMPYTDAVVHEIQR-YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 401
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
PNP+ FDP F N + + +PF G R C G A+++ + + + F +
Sbjct: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 76.6 bits (180), Expect = 1e-13
Identities = 59/238 (24%), Positives = 102/238 (42%), Gaps = 4/238 (1%)
Query: 94 FPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELT 153
FPG ++ K+V T R K + +D + R D K E E
Sbjct: 226 FPGTHNKVLKNVALTRSYIRE-KVKEHQASLD-VNNPRDFIDCFLIKMEQEKDNQKSEFN 283
Query: 154 DELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEML 213
E + ++AG ET++TT+ + L L +P++ KV EID + + +
Sbjct: 284 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR- 342
Query: 214 QNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYY 273
++ Y + +E R YS + P + + +I KGTT++ + HD+K +
Sbjct: 343 SHMPYTDAVVHEIQR-YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 401
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
PNP+ FDP F N + + +PF G R C G A+++ + + + F +
Sbjct: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 76.6 bits (180), Expect = 1e-13
Identities = 59/238 (24%), Positives = 102/238 (42%), Gaps = 4/238 (1%)
Query: 94 FPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELT 153
FPG ++ K+V T R K + +D + R D K E E
Sbjct: 226 FPGTHNKVLKNVALTRSYIRE-KVKEHQASLD-VNNPRDFIDCFLIKMEQEKDNQKSEFN 283
Query: 154 DELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEML 213
E + ++AG ET++TT+ + L L +P++ KV EID + + +
Sbjct: 284 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR- 342
Query: 214 QNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYY 273
++ Y + +E R YS + P + + +I KGTT++ + HD+K +
Sbjct: 343 SHMPYTDAVVHEIQR-YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 401
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
PNP+ FDP F N + + +PF G R C G A+++ + + + F +
Sbjct: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 75.8 bits (178), Expect = 2e-13
Identities = 59/238 (24%), Positives = 102/238 (42%), Gaps = 4/238 (1%)
Query: 94 FPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQLGDIQATKRNSEDKEYSIELT 153
FPG ++ K+V T R K + +D + R D K E E
Sbjct: 216 FPGTHNKVLKNVALTRSYIRE-KVKEHQASLD-VNNPRDFIDCFLIKMEQEKDNQKSEFN 273
Query: 154 DELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIAEIDQGLKESKGEVTYEML 213
E + ++AG ET++TT+ + L L +P++ KV EID + + +
Sbjct: 274 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR- 332
Query: 214 QNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIVIEKGTTVLFSPLGIHHDEKYY 273
++ Y + +E R YS + P + + +I KGTT++ + HD+K +
Sbjct: 333 SHMPYTDAVVHEIQR-YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 391
Query: 274 PNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRFAKIQSRVCMVKMFSKFRFE 331
PNP+ FDP F N + + +PF G R C G A+++ + + + F +
Sbjct: 392 PNPNIFDPGLFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 449
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 75.8 bits (178), Expect = 2e-13
Identities = 51/214 (23%), Positives = 97/214 (45%), Gaps = 3/214 (1%)
Query: 131 RQLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQ 190
R D K E E T E + A + AG ET++TT+ + L L P++
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 191 DKVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTD 250
KV EI+ + ++ + ++ Y + +E R ++ P + + +
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDR-SHMPYTDAVVHEIQRYIDLL-PTNLPHAVTCDVKFKN 378
Query: 251 IVIEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGM 310
+I KG T++ S + H++K +PNP FDP F + + + +PF G R C+G
Sbjct: 379 YLIPKGMTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGE 438
Query: 311 RFAKIQSRVCMVKMFSKFRFELAKNTPRNLDIDP 344
A+++ + + + F + ++ P+++DI P
Sbjct: 439 GLARMELFLFLTTILQNFNLK-SQVDPKDIDITP 471
>K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein.
Length = 331
Score = 75.8 bits (178), Expect = 2e-13
Identities = 63/274 (22%), Positives = 120/274 (43%), Gaps = 15/274 (5%)
Query: 73 NFAFELDMMYPGVLKKLNSTLFPGF-VSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALR 131
N +L M+ V+K+L F + + +D + +E P D N D I
Sbjct: 52 NSTGQLYEMFSSVMKQLPGPQQQAFQLLQGLEDFIAKKVEHNT--PLDPNSPRDFI---- 105
Query: 132 QLGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQD 191
D + E+K + E E + + +I G ET +TT+ + L +P ++
Sbjct: 106 ---DSFLIRMQEEEKNPNTEFYLEKLVMTSLNLFIGGTETVSTTLRYGFLLLIKHPGVEA 162
Query: 192 KVIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDI 251
KV EID+ + +++ + +E + Y E +E R ++ P+ ++ D
Sbjct: 163 KVHEEIDRVIGKNR-QPKFEDRAKMPYMEAMIHEIQRFGDVI-PMIWPGRVKKDTKFRDF 220
Query: 252 VIEKGTTVLFSPLG-IHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGM 310
+ KGT V + LG + D + P F+P+ F+ + + A +PF G NC G
Sbjct: 221 FLPKGTEV-YPMLGSVLRDPIFLSKPQDFNPQHFTELEGAPKKSDAFVPFSIGQPNCFGE 279
Query: 311 RFAKIQSRVCMVKMFSKFRFELAKNTPRNLDIDP 344
A+++ + + FR + + +P+++D+ P
Sbjct: 280 GLARMELFLFFTTVMQNFRLK-SSQSPKDIDVSP 312
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 75.4 bits (177), Expect = 3e-13
Identities = 65/262 (24%), Positives = 115/262 (43%), Gaps = 13/262 (4%)
Query: 74 FAFELDMMYPGVLKKLNSTLFPGFVSRFFKDVVKTIIEQRNGKPTDRNDFMDLILALRQL 133
F D + +L +N F +F+ + K + E K ++ D+ +L
Sbjct: 203 FGRRYDHNHQELLSLVNLNAFKDLNEKFYSFMQKMVKEHY--KTFEKGHIRDITDSL--- 257
Query: 134 GDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKV 193
I+ + D+ +++L+DE I + AG++T T +++ L L +NP +Q K+
Sbjct: 258 --IEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKI 315
Query: 194 IAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIV 252
E+D + S+ + +L Y E ET R S V + + D +
Sbjct: 316 QEELDTVIGRSRRPRLSDR-SHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL--KGFY 372
Query: 253 IEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH--IPFGTGPRNCIGM 310
I KG V + I+HD+K + NPS+F PERF + + + I FG G R CIG
Sbjct: 373 IPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGE 432
Query: 311 RFAKIQSRVCMVKMFSKFRFEL 332
A+ + + + + + F +
Sbjct: 433 TIARWEVFLFLAILLQRVEFSV 454
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.5 bits (175), Expect = 5e-13
Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 7/206 (3%)
Query: 133 LGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDK 192
L +++ K N E DE + + AG T++TT+ + L + L+PD+Q +
Sbjct: 276 LAEMEKAKGNPESS-----FNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRR 330
Query: 193 VIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIV 252
V EID + + + + ++ Y +E R IV PL I
Sbjct: 331 VQQEIDDVIGQVRRPEMGDQA-HMPYTTAVIHEVQRFGDIV-PLGVTHMTSRDIEVQGFR 388
Query: 253 IEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRF 312
I KGTT++ + + DE + P +F PE F A P A +PF G R C+G
Sbjct: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPL 448
Query: 313 AKIQSRVCMVKMFSKFRFELAKNTPR 338
A+++ + + F F +A PR
Sbjct: 449 ARMELFLFFTSLLQHFSFSVAAGQPR 474
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 73.7 bits (173), Expect = 9e-13
Identities = 54/200 (27%), Positives = 94/200 (47%), Gaps = 6/200 (3%)
Query: 136 IQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDKVIA 195
I+ + D+ +++L+DE I + AG++T T +++ L L +NP +Q K+
Sbjct: 286 IEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQE 345
Query: 196 EIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVE-PLQRNAKIDYKIPDTDIVIE 254
E+D + S+ + +L Y E ET R S+V + + D + I
Sbjct: 346 ELDTVIGRSRRPRLSDR-SHLPYMEAFILETFRHSSLVPFTIPHSTTRDTSL--KGFYIP 402
Query: 255 KGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAH--IPFGTGPRNCIGMRF 312
KG V + I+HD+K + NPS+F PERF + + + I FG G R CIG
Sbjct: 403 KGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETV 462
Query: 313 AKIQSRVCMVKMFSKFRFEL 332
A+ + + + + + F +
Sbjct: 463 ARWEVFLFLAILLQRVEFSV 482
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 73.3 bits (172), Expect = 1e-12
Identities = 54/206 (26%), Positives = 88/206 (42%), Gaps = 7/206 (3%)
Query: 133 LGDIQATKRNSEDKEYSIELTDELIEAQAFVFYIAGYETSATTMTFMLYQLALNPDIQDK 192
L +++ K N E DE + + AG T++TT+ + L + L+PD+Q +
Sbjct: 276 LAEMEKAKGNPESS-----FNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRR 330
Query: 193 VIAEIDQGLKESKGEVTYEMLQNLTYFEKAFNETLRMYSIVEPLQRNAKIDYKIPDTDIV 252
V EID + + + + ++ Y +E R IV PL I
Sbjct: 331 VQQEIDDVIGQVRRPEMGDQA-HMPYTTAVIHEVQRFGDIV-PLGMTHMTSRDIEVQGFR 388
Query: 253 IEKGTTVLFSPLGIHHDEKYYPNPSKFDPERFSPANISARHPCAHIPFGTGPRNCIGMRF 312
I KGTT++ + + DE + P +F PE F A P A +PF G R C+G
Sbjct: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPL 448
Query: 313 AKIQSRVCMVKMFSKFRFELAKNTPR 338
A+++ + + F F + PR
Sbjct: 449 ARMELFLFFTSLLQHFSFSVPTGQPR 474
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.137 0.399
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 48,586,851
Number of Sequences: 224733
Number of extensions: 2037723
Number of successful extensions: 7460
Number of sequences better than 10.0: 447
Number of HSP's better than 10.0 without gapping: 400
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 6326
Number of HSP's gapped (non-prelim): 501
length of query: 362
length of database: 73,234,838
effective HSP length: 91
effective length of query: 271
effective length of database: 52,784,135
effective search space: 14304500585
effective search space used: 14304500585
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 66 (30.7 bits)
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