Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001401-TA|BGIBMGA001401-PA|IPR003000|Silent information
regulator protein Sir2
(370 letters)
Database: fruitfly
52,641 sequences; 24,830,863 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AE014297-1127|AAF54513.1| 317|Drosophila melanogaster CG6284-PA... 389 e-108
AY061405-1|AAL28953.1| 500|Drosophila melanogaster LD33358p pro... 144 1e-34
AE014297-4312|AAF56851.2| 771|Drosophila melanogaster CG11305-P... 144 1e-34
AY071228-1|AAL48850.1| 326|Drosophila melanogaster RE26822p pro... 51 2e-06
AE014297-2781|AAG22161.1| 355|Drosophila melanogaster CG5085-PA... 51 2e-06
BT011040-1|AAR30200.1| 312|Drosophila melanogaster GH08671p pro... 50 5e-06
AE014298-765|AAN09146.2| 312|Drosophila melanogaster CG3187-PC,... 50 5e-06
BT004901-1|AAO47879.1| 483|Drosophila melanogaster LD07439p pro... 47 5e-05
AF068758-1|AAC79684.1| 823|Drosophila melanogaster SIR2 protein. 47 5e-05
AE014134-2285|AAF53248.1| 823|Drosophila melanogaster CG5216-PA... 47 5e-05
AE014298-767|AAN09147.2| 229|Drosophila melanogaster CG3187-PB,... 38 0.017
AE014298-766|AAF46055.3| 229|Drosophila melanogaster CG3187-PA,... 38 0.017
AY089412-1|AAL90150.1| 249|Drosophila melanogaster AT23505p pro... 30 4.5
AY061453-1|AAL29001.1| 985|Drosophila melanogaster LD39136p pro... 30 4.5
AE013599-1040|AAF58831.2| 985|Drosophila melanogaster CG18011-P... 30 4.5
>AE014297-1127|AAF54513.1| 317|Drosophila melanogaster CG6284-PA
protein.
Length = 317
Score = 389 bits (958), Expect = e-108
Identities = 183/309 (59%), Positives = 232/309 (75%), Gaps = 4/309 (1%)
Query: 1 MSCNYAEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAG 60
MSCNYA+GLS Y+NKGILG PE FDS++ + +KC LA+L+K S H+V+HTGAGISTSAG
Sbjct: 1 MSCNYADGLSAYDNKGILGAPESFDSDEVVAEKCQELAELIKKSGHVVLHTGAGISTSAG 60
Query: 61 IPDFRGPNGVWTLEKEGKKPTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHL 120
IPDFRGP GVWTLE++G+KP NVSF +A+PTKTHM +SQNIDGLHL
Sbjct: 61 IPDFRGPKGVWTLEEKGEKPDFNVSFDEARPTKTHMAIIALIESGYVQYVISQNIDGLHL 120
Query: 121 KSGVPRKFLAELHGNMFIDECNICKRQFVRSSPVETVGKKCSGVPC-AAHHVTGRPCR-G 178
KSG+ RK+L+ELHGN++I++C C+RQFV S VETVG+K C ++ GR CR G
Sbjct: 121 KSGLDRKYLSELHGNIYIEQCKKCRRQFVSPSAVETVGQKSLQRACKSSMDSKGRSCRSG 180
Query: 179 RLYDGVLDWEHSLPENDLLMAEWHSSIADLSICLGTTLQIVPSGNLPLETIKYGGKLVIC 238
LYD VLDWEH LPENDL M HS++ADL+I LGTTLQIVPSG+LPL+ +K GGK VIC
Sbjct: 181 ILYDNVLDWEHDLPENDLEMGVMHSTVADLNIALGTTLQIVPSGDLPLKNLKCGGKFVIC 240
Query: 239 NLQPTKHDNKADLLINYYVDDVLEKVMDILGIEIPSYNESENPMKFAETAIIDWSIDRKD 298
NLQPTKHD KA+L+I+ YVD VL KV +LG+EIP Y+E+ +P K ++ ++W+I +
Sbjct: 241 NLQPTKHDKKANLIISSYVDVVLSKVCKLLGVEIPEYSEASDPTK--QSKPMEWTIPTSN 298
Query: 299 VLALEKTFK 307
V + +K
Sbjct: 299 VNTFHRQYK 307
>AY061405-1|AAL28953.1| 500|Drosophila melanogaster LD33358p
protein.
Length = 500
Score = 144 bits (350), Expect = 1e-34
Identities = 90/278 (32%), Positives = 146/278 (52%), Gaps = 12/278 (4%)
Query: 20 VPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKK 79
V E+ D+ + K LA ++ +KH+V +TGAGIST+A IPD+RG G+WTL ++G+
Sbjct: 99 VVEREDAPHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQKGQD 158
Query: 80 PTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFLAELHGNMFID 139
+ + A PT THM VSQN DGLHL+SG+PR L+E+HGNM+++
Sbjct: 159 IGEH-DLSSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSEIHGNMYVE 217
Query: 140 ECNICKRQFVRSSPVETVGKKCSGVPCAAHHVTGRPCRGRLYDGVLDWEH----SLPEND 195
C C+ V +T + + C H C LYD ++ + P N
Sbjct: 218 VCKNCRPNSVYWRQFDTT--EMTARYCHKTHRLCHRCSEPLYDTIVHFGERGNVKWPLN- 274
Query: 196 LLMAEWHSSIADLSICLGTTLQIVPSGNLPLE---TIKYGGKLVICNLQPTKHDNKADLL 252
A ++ AD+ +CLG++L+++ + + K+ + NLQ T D A +
Sbjct: 275 WAGATANAQRADVILCLGSSLKVLKKYTWLWQMDRPARQRAKICVVNLQWTPKDAIASIK 334
Query: 253 INYYVDDVLEKVMDILGIEIPSYNESENPMKFAETAII 290
IN D V+ ++M +L I +P Y + ++P+ FA +++
Sbjct: 335 INGKCDQVMAQLMHLLHIPVPVYTKEKDPI-FAHASLL 371
>AE014297-4312|AAF56851.2| 771|Drosophila melanogaster CG11305-PA
protein.
Length = 771
Score = 144 bits (350), Expect = 1e-34
Identities = 90/278 (32%), Positives = 146/278 (52%), Gaps = 12/278 (4%)
Query: 20 VPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKK 79
V E+ D+ + K LA ++ +KH+V +TGAGIST+A IPD+RG G+WTL ++G+
Sbjct: 99 VVEREDAPHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQKGQD 158
Query: 80 PTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFLAELHGNMFID 139
+ + A PT THM VSQN DGLHL+SG+PR L+E+HGNM+++
Sbjct: 159 IGEH-DLSSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSEIHGNMYVE 217
Query: 140 ECNICKRQFVRSSPVETVGKKCSGVPCAAHHVTGRPCRGRLYDGVLDWEH----SLPEND 195
C C+ V +T + + C H C LYD ++ + P N
Sbjct: 218 VCKNCRPNSVYWRQFDTT--EMTARYCHKTHRLCHRCSEPLYDTIVHFGERGNVKWPLN- 274
Query: 196 LLMAEWHSSIADLSICLGTTLQIVPSGNLPLE---TIKYGGKLVICNLQPTKHDNKADLL 252
A ++ AD+ +CLG++L+++ + + K+ + NLQ T D A +
Sbjct: 275 WAGATANAQRADVILCLGSSLKVLKKYTWLWQMDRPARQRAKICVVNLQWTPKDAIASIK 334
Query: 253 INYYVDDVLEKVMDILGIEIPSYNESENPMKFAETAII 290
IN D V+ ++M +L I +P Y + ++P+ FA +++
Sbjct: 335 INGKCDQVMAQLMHLLHIPVPVYTKEKDPI-FAHASLL 371
>AY071228-1|AAL48850.1| 326|Drosophila melanogaster RE26822p
protein.
Length = 326
Score = 51.2 bits (117), Expect = 2e-06
Identities = 56/203 (27%), Positives = 88/203 (43%), Gaps = 32/203 (15%)
Query: 45 KHIVVHTGAGISTSAGIPDFRGP-NGVWT-LEK-EGKKPTINVS-----------FADAQ 90
+ IV GAGISTSAGIPDFR P +G+++ L+K E PT FA A+
Sbjct: 79 RKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPAPFFALAK 138
Query: 91 --------PTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFLAELHGNMFIDECN 142
PT H +QNID L +G+P + E HG+ + C
Sbjct: 139 ELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHCI 198
Query: 143 ICKRQF-VRSSPVETVGKKCSGVPCAAHHVTGRPCRGRLYDGVLDWEHSLPENDLLMAEW 201
C++++ + E + C + C+G + ++ + +LP+ E
Sbjct: 199 KCRKEYDMDWMKAEIFADRLP--KC-------QKCQGVVKPDIVFFGENLPKRFYSSPEE 249
Query: 202 HSSIADLSICLGTTLQIVPSGNL 224
DL I +GT+L++ P +L
Sbjct: 250 DFQDCDLLIIMGTSLEVQPFASL 272
>AE014297-2781|AAG22161.1| 355|Drosophila melanogaster CG5085-PA
protein.
Length = 355
Score = 51.2 bits (117), Expect = 2e-06
Identities = 56/203 (27%), Positives = 88/203 (43%), Gaps = 32/203 (15%)
Query: 45 KHIVVHTGAGISTSAGIPDFRGP-NGVWT-LEK-EGKKPTINVS-----------FADAQ 90
+ IV GAGISTSAGIPDFR P +G+++ L+K E PT FA A+
Sbjct: 48 RKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPAPFFALAK 107
Query: 91 --------PTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFLAELHGNMFIDECN 142
PT H +QNID L +G+P + E HG+ + C
Sbjct: 108 ELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHCI 167
Query: 143 ICKRQF-VRSSPVETVGKKCSGVPCAAHHVTGRPCRGRLYDGVLDWEHSLPENDLLMAEW 201
C++++ + E + C + C+G + ++ + +LP+ E
Sbjct: 168 KCRKEYDMDWMKAEIFADRLP--KC-------QKCQGVVKPDIVFFGENLPKRFYSSPEE 218
Query: 202 HSSIADLSICLGTTLQIVPSGNL 224
DL I +GT+L++ P +L
Sbjct: 219 DFQDCDLLIIMGTSLEVQPFASL 241
>BT011040-1|AAR30200.1| 312|Drosophila melanogaster GH08671p
protein.
Length = 312
Score = 50.0 bits (114), Expect = 5e-06
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 24/135 (17%)
Query: 37 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA------- 89
L + +++V TGAGIST +GIPD+R GV + KP ++ F +
Sbjct: 38 LEDFLLSKPNVLVLTGAGISTESGIPDYRS-EGVGLYARSNHKPVQHMEFVKSSAVRKRY 96
Query: 90 --------------QPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFLAELHGN 135
QP TH V+QN+D LH K+G + + E+HG+
Sbjct: 97 WARNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNVVEVHGS 154
Query: 136 MFIDECNICKRQFVR 150
++ +C C+ + R
Sbjct: 155 GYVVKCLSCEYRIDR 169
>AE014298-765|AAN09146.2| 312|Drosophila melanogaster CG3187-PC,
isoform C protein.
Length = 312
Score = 50.0 bits (114), Expect = 5e-06
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 24/135 (17%)
Query: 37 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA------- 89
L + +++V TGAGIST +GIPD+R GV + KP ++ F +
Sbjct: 38 LEDFLLSKPNVLVLTGAGISTESGIPDYRS-EGVGLYARSNHKPVQHMEFVKSSAVRKRY 96
Query: 90 --------------QPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFLAELHGN 135
QP TH V+QN+D LH K+G + + E+HG+
Sbjct: 97 WARNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNVVEVHGS 154
Query: 136 MFIDECNICKRQFVR 150
++ +C C+ + R
Sbjct: 155 GYVVKCLSCEYRIDR 169
>BT004901-1|AAO47879.1| 483|Drosophila melanogaster LD07439p
protein.
Length = 483
Score = 46.8 bits (106), Expect = 5e-05
Identities = 20/32 (62%), Positives = 25/32 (78%)
Query: 40 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 71
LVK S+ I+V TGAG+S S GIPDFR NG++
Sbjct: 217 LVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIY 248
>AF068758-1|AAC79684.1| 823|Drosophila melanogaster SIR2 protein.
Length = 823
Score = 46.8 bits (106), Expect = 5e-05
Identities = 20/32 (62%), Positives = 25/32 (78%)
Query: 40 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 71
LVK S+ I+V TGAG+S S GIPDFR NG++
Sbjct: 215 LVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIY 246
>AE014134-2285|AAF53248.1| 823|Drosophila melanogaster CG5216-PA
protein.
Length = 823
Score = 46.8 bits (106), Expect = 5e-05
Identities = 20/32 (62%), Positives = 25/32 (78%)
Query: 40 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 71
LVK S+ I+V TGAG+S S GIPDFR NG++
Sbjct: 217 LVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIY 248
>AE014298-767|AAN09147.2| 229|Drosophila melanogaster CG3187-PB,
isoform B protein.
Length = 229
Score = 38.3 bits (85), Expect = 0.017
Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 86 FADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFLAELHGNMFIDECNICK 145
F+ QP TH V+QN+D LH K+G + + E+HG+ ++ +C C+
Sbjct: 24 FSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNVVEVHGSGYVVKCLSCE 81
Query: 146 RQFVR 150
+ R
Sbjct: 82 YRIDR 86
>AE014298-766|AAF46055.3| 229|Drosophila melanogaster CG3187-PA,
isoform A protein.
Length = 229
Score = 38.3 bits (85), Expect = 0.017
Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 86 FADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFLAELHGNMFIDECNICK 145
F+ QP TH V+QN+D LH K+G + + E+HG+ ++ +C C+
Sbjct: 24 FSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNVVEVHGSGYVVKCLSCE 81
Query: 146 RQFVR 150
+ R
Sbjct: 82 YRIDR 86
>AY089412-1|AAL90150.1| 249|Drosophila melanogaster AT23505p
protein.
Length = 249
Score = 30.3 bits (65), Expect = 4.5
Identities = 12/31 (38%), Positives = 19/31 (61%)
Query: 133 HGNMFIDECNICKRQFVRSSPVETVGKKCSG 163
H F ECN+CK++F RS ++T ++ G
Sbjct: 120 HYKRFAFECNVCKKRFGRSQGLKTHMQRAHG 150
>AY061453-1|AAL29001.1| 985|Drosophila melanogaster LD39136p
protein.
Length = 985
Score = 30.3 bits (65), Expect = 4.5
Identities = 12/31 (38%), Positives = 19/31 (61%)
Query: 133 HGNMFIDECNICKRQFVRSSPVETVGKKCSG 163
H F ECN+CK++F RS ++T ++ G
Sbjct: 856 HYKRFAFECNVCKKRFGRSQGLKTHMQRAHG 886
>AE013599-1040|AAF58831.2| 985|Drosophila melanogaster CG18011-PA
protein.
Length = 985
Score = 30.3 bits (65), Expect = 4.5
Identities = 12/31 (38%), Positives = 19/31 (61%)
Query: 133 HGNMFIDECNICKRQFVRSSPVETVGKKCSG 163
H F ECN+CK++F RS ++T ++ G
Sbjct: 856 HYKRFAFECNVCKKRFGRSQGLKTHMQRAHG 886
Database: fruitfly
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 24,830,863
Number of sequences in database: 52,641
Lambda K H
0.316 0.135 0.404
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 18,736,752
Number of Sequences: 52641
Number of extensions: 820599
Number of successful extensions: 2006
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1973
Number of HSP's gapped (non-prelim): 28
length of query: 370
length of database: 24,830,863
effective HSP length: 86
effective length of query: 284
effective length of database: 20,303,737
effective search space: 5766261308
effective search space used: 5766261308
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 63 (29.5 bits)
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