Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001386-TA|BGIBMGA001386-PA|IPR000842|Phosphoribosyl
pyrophosphate synthetase, IPR005946|Ribose-phosphate
pyrophosphokinase, IPR000836|Phosphoribosyltransferase
(365 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VT33 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 602 e-171
UniRef50_P60891 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 584 e-166
UniRef50_UPI000156094F Cluster: PREDICTED: similar to PRPS2 prot... 510 e-143
UniRef50_Q4P1D3 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 402 e-111
UniRef50_UPI0000EB04C8 Cluster: UPI0000EB04C8 related cluster; n... 345 1e-93
UniRef50_A7M6E2 Cluster: Ribose-phosphate pyrophosphokinase I; n... 341 2e-92
UniRef50_UPI00005A2C8C Cluster: PREDICTED: similar to Ribose-pho... 325 1e-87
UniRef50_Q5KCA3 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 317 3e-85
UniRef50_UPI00015B404E Cluster: PREDICTED: similar to ENSANGP000... 313 4e-84
UniRef50_Q75JN8 Cluster: Similar to ribose-phosphate pyrophospho... 306 6e-82
UniRef50_Q8R753 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 296 7e-79
UniRef50_Q89DJ1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 295 2e-78
UniRef50_Q88Z84 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 292 8e-78
UniRef50_Q1GEV9 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 289 1e-76
UniRef50_A3ZLP4 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 288 2e-76
UniRef50_Q9U465 Cluster: Phosphoribosylpyrophosphate synthetase;... 287 3e-76
UniRef50_Q7MT83 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 283 7e-75
UniRef50_P65239 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 282 9e-75
UniRef50_Q42581 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 282 1e-74
UniRef50_A0VM43 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 280 5e-74
UniRef50_A4T068 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 274 2e-72
UniRef50_Q4P9A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 274 3e-72
UniRef50_A4EBQ1 Cluster: Putative uncharacterized protein; n=1; ... 267 3e-70
UniRef50_Q1AXL6 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 266 5e-70
UniRef50_Q9RUD2 Cluster: Probable ribose-phosphate pyrophosphoki... 264 2e-69
UniRef50_A4VV92 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 264 2e-69
UniRef50_Q4Q3Z4 Cluster: Phosphoribosylpyrophosphate synthetase,... 259 7e-68
UniRef50_A6R925 Cluster: Ribose-phosphate pyrophosphokinase I; n... 259 9e-68
UniRef50_Q6MAT0 Cluster: Probable phosphoribosyl pyrophosphate s... 256 7e-67
UniRef50_Q5A4X7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 254 3e-66
UniRef50_A5V1W5 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 250 3e-65
UniRef50_Q83GR1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 248 1e-64
UniRef50_Q1DW45 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 246 7e-64
UniRef50_Q4Q0M2 Cluster: Phosphoribosylpyrophosphate synthetase,... 245 1e-63
UniRef50_A5URX1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 243 7e-63
UniRef50_A0CY99 Cluster: Chromosome undetermined scaffold_31, wh... 242 1e-62
UniRef50_P32895 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 241 2e-62
UniRef50_A7TNR7 Cluster: Putative uncharacterized protein; n=1; ... 239 8e-62
UniRef50_Q8G5P2 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 239 1e-61
UniRef50_Q8Y9L8 Cluster: Ribose-phosphate pyrophosphokinase 2; n... 239 1e-61
UniRef50_A1CDQ3 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 235 1e-60
UniRef50_A7EV32 Cluster: Putative uncharacterized protein; n=1; ... 230 4e-59
UniRef50_P75044 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 230 4e-59
UniRef50_Q6F241 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 230 5e-59
UniRef50_Q4QI56 Cluster: Phosphoribosylpyrophosphate synthetase;... 230 5e-59
UniRef50_Q6CG51 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 229 7e-59
UniRef50_Q8X022 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 229 9e-59
UniRef50_Q3M5L4 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 228 2e-58
UniRef50_Q8EUI1 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 225 1e-57
UniRef50_A7ARJ1 Cluster: Ribose-phosphate pyrophosphokinase, put... 223 8e-57
UniRef50_Q8D2K5 Cluster: PrsA protein; n=1; Wigglesworthia gloss... 222 1e-56
UniRef50_Q03YB5 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 219 7e-56
UniRef50_Q822W0 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 217 4e-55
UniRef50_Q74LT0 Cluster: Phosphoribosylpyrophosphate synthetase;... 217 4e-55
UniRef50_Q0G092 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 214 3e-54
UniRef50_Q9EWS0 Cluster: Putative ribose-phosphate pyrophosphoki... 213 8e-54
UniRef50_Q16GA3 Cluster: Ribose-phosphate pyrophosphokinase 1, p... 212 1e-53
UniRef50_Q9PQV0 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 207 4e-52
UniRef50_O62580 Cluster: Phosphoribosyl pyrophosphate synthetase... 205 1e-51
UniRef50_Q6MW31 Cluster: Related to ribose-phosphate pyrophospho... 201 2e-50
UniRef50_Q98R83 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 200 6e-50
UniRef50_A7HHV4 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 192 1e-47
UniRef50_A0E424 Cluster: Chromosome undetermined scaffold_77, wh... 190 5e-47
UniRef50_O60256 Cluster: Phosphoribosyl pyrophosphate synthetase... 190 6e-47
UniRef50_Q2S5C7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 185 2e-45
UniRef50_A3LVW1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 184 2e-45
UniRef50_Q4UNC9 Cluster: Ribose-phosphate pyrophosphokinase; n=9... 182 2e-44
UniRef50_A5DKD0 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 179 9e-44
UniRef50_Q5GTH9 Cluster: Phosphoribosylpyrophosphate synthetase;... 178 2e-43
UniRef50_A4BQ39 Cluster: Ribose-phosphate pyrophosphokinase; n=9... 175 1e-42
UniRef50_Q0U4M1 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 171 2e-41
UniRef50_Q2GIZ1 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 164 3e-39
UniRef50_Q3YQZ8 Cluster: Ribose-phosphate pyrophospho kinase; n=... 160 5e-38
UniRef50_A2AAG9 Cluster: Likely ortholog of H. sapiens phosphori... 154 3e-36
UniRef50_O26877 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 153 9e-36
UniRef50_Q4XQD5 Cluster: Ribose-phosphate pyrophosphokinase, put... 151 2e-35
UniRef50_UPI00006CD8E2 Cluster: ribose-phosphate pyrophosphokina... 148 2e-34
UniRef50_Q8TUT6 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 144 2e-33
UniRef50_Q2GCV8 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 144 3e-33
UniRef50_Q8KKS6 Cluster: Ribose-phosphate pyrophosphokinase prot... 138 2e-31
UniRef50_Q58761 Cluster: Ribose-phosphate pyrophosphokinase; n=7... 138 2e-31
UniRef50_UPI00015BACA3 Cluster: ribose-phosphate pyrophosphokina... 138 2e-31
UniRef50_A3DNX0 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 138 2e-31
UniRef50_O59586 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 138 2e-31
UniRef50_O83317 Cluster: Phosphoribosyl pyrophosphate synthetase... 130 4e-29
UniRef50_Q660Y0 Cluster: Phosphoribosyl pyrophosphate synthetase... 130 7e-29
UniRef50_A7DQD3 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 127 4e-28
UniRef50_A4WYL1 Cluster: Putative uncharacterized protein; n=1; ... 126 1e-27
UniRef50_Q6Z2L5-2 Cluster: Isoform 2 of Q6Z2L5 ; n=1; Oryza sati... 125 2e-27
UniRef50_A3H7E6 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 124 5e-27
UniRef50_Q12265 Cluster: Probable ribose-phosphate pyrophosphoki... 123 6e-27
UniRef50_Q97Z86 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 120 6e-26
UniRef50_Q6L0L1 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 118 2e-25
UniRef50_O28853 Cluster: Ribose-phosphate pyrophosphokinase 2; n... 118 2e-25
UniRef50_Q222A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 117 6e-25
UniRef50_Q88JA5 Cluster: Ribose-phosphate pyrophosphokinase fami... 116 1e-24
UniRef50_Q8IE40 Cluster: Ribose-phosphate pyrophosphokinase, put... 115 2e-24
UniRef50_Q9HLV6 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 115 2e-24
UniRef50_Q8ZU24 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 113 5e-24
UniRef50_Q9YAW0 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 112 1e-23
UniRef50_Q5ZWR2 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 111 2e-23
UniRef50_A1RWZ6 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 110 5e-23
UniRef50_Q8PUX3 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 109 1e-22
UniRef50_A1ZM86 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 108 3e-22
UniRef50_A2BKK7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 108 3e-22
UniRef50_A0RYR1 Cluster: Phosphoribosylpyrophosphate synthetase;... 107 3e-22
UniRef50_A4CGY8 Cluster: Phosphoribosylpyrophosphate synthetase;... 107 4e-22
UniRef50_Q0W4S8 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 107 4e-22
UniRef50_A3CS59 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 107 4e-22
UniRef50_A1RX65 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 106 8e-22
UniRef50_Q11BI1 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 105 2e-21
UniRef50_Q075L4 Cluster: Plastid ribose-phosphate diphosphokinas... 104 4e-21
UniRef50_A7MKK1 Cluster: Putative uncharacterized protein; n=1; ... 99 9e-20
UniRef50_Q9HN88 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 99 2e-19
UniRef50_O29666 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 97 8e-19
UniRef50_Q607P3 Cluster: Ribose-phosphate pyrophosphokinase fami... 93 8e-18
UniRef50_Q12E98 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 92 2e-17
UniRef50_A3W7X1 Cluster: Phosphoribosylpyrophosphate synthetase;... 89 2e-16
UniRef50_Q1GQ93 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 88 3e-16
UniRef50_Q2SLU9 Cluster: Phosphoribosylpyrophosphate synthetase;... 87 7e-16
UniRef50_A2X0F3 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 86 1e-15
UniRef50_A4XET1 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 85 4e-15
UniRef50_Q89QK8 Cluster: Bll3116 protein; n=5; Bradyrhizobiaceae... 84 5e-15
UniRef50_Q6KG64 Cluster: Putative uncharacterized protein; n=2; ... 83 1e-14
UniRef50_Q4DSS9 Cluster: Ribose-phosphate pyrophosphokinase, put... 83 1e-14
UniRef50_A6BI68 Cluster: Putative uncharacterized protein; n=2; ... 81 4e-14
UniRef50_A4FCC2 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 81 4e-14
UniRef50_Q4QIB8 Cluster: Ribose-phosphate pyrophosphokinase, put... 81 4e-14
UniRef50_A1HDW3 Cluster: Ribose-phosphate diphosphokinase; n=3; ... 81 6e-14
UniRef50_Q93Z66 Cluster: Ribose-phosphate pyrophosphokinase 3; n... 80 1e-13
UniRef50_Q1FFM9 Cluster: Ribose-phosphate pyrophosphokinase; n=8... 79 1e-13
UniRef50_Q21W91 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 78 3e-13
UniRef50_A7B5K6 Cluster: Putative uncharacterized protein; n=1; ... 77 5e-13
UniRef50_Q97KU7 Cluster: Phosphoribosylpyrophosphate synthetase;... 75 2e-12
UniRef50_UPI00004989B9 Cluster: ribose-phosphate pyrophosphokina... 74 5e-12
UniRef50_Q7XZ65 Cluster: Phosphoribosyl pyrophosphate synthetase... 72 2e-11
UniRef50_A2FWD0 Cluster: Ribose-phosphate pyrophosphokinase fami... 71 5e-11
UniRef50_Q4FCY7 Cluster: Phosphoribosyl pyrophosphate synthetase... 69 1e-10
UniRef50_Q8KTQ3 Cluster: Phosphoribosylpyrophosphate synthetase;... 69 3e-10
UniRef50_Q11SD6 Cluster: Phosphoribosylpyrophosphate synthetase;... 69 3e-10
UniRef50_Q6FDK1 Cluster: Putative ribose-phosphate pyrophosphoki... 66 2e-09
UniRef50_A6LV64 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 66 2e-09
UniRef50_Q680A5 Cluster: Ribose-phosphate pyrophosphokinase 4; n... 66 2e-09
UniRef50_Q7P228 Cluster: Probable ribose-phosphate diphosphokina... 63 1e-08
UniRef50_Q0U4M2 Cluster: Putative uncharacterized protein; n=1; ... 63 1e-08
UniRef50_Q64M76 Cluster: Phosphoribosyl pyrophosphate synthase-l... 61 4e-08
UniRef50_Q8EFJ2 Cluster: Phosphoribosyl transferase domain prote... 61 5e-08
UniRef50_A6DTG6 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 59 2e-07
UniRef50_A2FHP9 Cluster: Ribose-phosphate pyrophosphokinase fami... 59 2e-07
UniRef50_A6VUG9 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 56 1e-06
UniRef50_A6MK41 Cluster: Phosphoribosyl pyrophosphate synthetase... 56 2e-06
UniRef50_A7SHY8 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 54 6e-06
UniRef50_A0CXZ2 Cluster: Chromosome undetermined scaffold_30, wh... 52 2e-05
UniRef50_P58860 Cluster: Orotate phosphoribosyltransferase; n=1;... 46 0.002
UniRef50_A2XQT7 Cluster: Putative uncharacterized protein; n=1; ... 45 0.004
UniRef50_Q2FPQ2 Cluster: Orotate phosphoribosyltransferase; n=4;... 44 0.005
UniRef50_Q12V34 Cluster: PyrE-like protein; n=2; Methanosarcinac... 42 0.025
UniRef50_Q30L82 Cluster: Gp63; n=1; Listeria phage P100|Rep: Gp6... 42 0.033
UniRef50_Q9K9W3 Cluster: Orotate phosphoribosyltransferase; n=54... 42 0.033
UniRef50_Q8FRQ5 Cluster: Uracil phosphoribosyltransferase; n=28;... 41 0.044
UniRef50_O08359 Cluster: Orotate phosphoribosyltransferase; n=4;... 40 0.10
UniRef50_A2BJ25 Cluster: Orotate phosphoribosyltransferase; n=1;... 39 0.18
UniRef50_UPI00015BABBC Cluster: phosphoribosyltransferase; n=1; ... 39 0.24
UniRef50_A0Y8V6 Cluster: Competence protein ComF, putative; n=1;... 38 0.31
UniRef50_Q314R1 Cluster: ComF family protein; n=1; Desulfovibrio... 38 0.54
UniRef50_Q26998 Cluster: Uracil phosphoribosyltransferase; n=15;... 37 0.72
UniRef50_Q4Z9R5 Cluster: ORF031; n=2; unclassified Myoviridae|Re... 37 0.95
UniRef50_O58855 Cluster: Orotate phosphoribosyltransferase; n=3;... 37 0.95
UniRef50_UPI00015BD983 Cluster: UPI00015BD983 related cluster; n... 36 1.3
UniRef50_A2U7L3 Cluster: Late competence protein; n=1; Bacillus ... 36 1.3
UniRef50_A4FCI4 Cluster: Phosphoribosyltransferase; n=1; Sacchar... 36 1.7
UniRef50_Q4Q3E4 Cluster: Putative uncharacterized protein; n=3; ... 36 1.7
UniRef50_Q0S3S3 Cluster: Possible phosphoribosyltransferase; n=1... 36 2.2
UniRef50_Q5KV55 Cluster: Late competence protein; n=2; Geobacill... 35 2.9
UniRef50_Q1VXI5 Cluster: Hypoxanthine-guanine phosphoribosyltran... 35 2.9
UniRef50_Q5FFA1 Cluster: Similar to competence protein F; n=2; E... 35 3.8
UniRef50_Q3IJQ7 Cluster: Putative uncharacterized protein; n=2; ... 35 3.8
UniRef50_A1TIR0 Cluster: Rhs element Vgr protein; n=15; cellular... 35 3.8
UniRef50_Q8N427 Cluster: Thioredoxin domain-containing protein 3... 35 3.8
UniRef50_Q1AVJ4 Cluster: Phosphoribosyltransferase; n=1; Rubroba... 34 5.1
UniRef50_Q04H27 Cluster: Orotate phosphoribosyltransferase; n=1;... 34 5.1
UniRef50_A0IM27 Cluster: Rhs element Vgr protein; n=4; Enterobac... 34 5.1
UniRef50_A0DXS4 Cluster: Chromosome undetermined scaffold_69, wh... 34 5.1
UniRef50_Q41CE1 Cluster: Late competence protein; n=1; Exiguobac... 34 6.7
UniRef50_A7TEN3 Cluster: Putative uncharacterized protein; n=1; ... 34 6.7
UniRef50_Q97PP4 Cluster: Phosphoglucosamine mutase; n=67; Bacter... 34 6.7
UniRef50_Q39CP3 Cluster: Phosphoribosyltransferase; n=30; Burkho... 33 8.9
UniRef50_Q7XY42 Cluster: Oxidoreductase; n=1; Griffithsia japoni... 33 8.9
UniRef50_A3DM49 Cluster: Orotate phosphoribosyltransferase; n=1;... 33 8.9
>UniRef50_Q9VT33 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Fungi/Metazoa group|Rep: Ribose-phosphate
pyrophosphokinase - Drosophila melanogaster (Fruit fly)
Length = 388
Score = 602 bits (1487), Expect = e-171
Identities = 297/343 (86%), Positives = 314/343 (91%), Gaps = 23/343 (6%)
Query: 46 TRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQS 105
+RMPNIKVFSG+SHPDLAQ+IVDRLGIDLGKVVTKKFSN+ETCVEIGESVRGEDVYIVQS
Sbjct: 46 SRMPNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQS 105
Query: 106 GSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDK---------------- 149
GSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDK
Sbjct: 106 GSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKK 165
Query: 150 -------SRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWI 202
SRAPI+AKLVAN+LSV+GADHIITMDLHASQIQGFFDIPVDNL+AEPAVLKWI
Sbjct: 166 NYDWKFRSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWI 225
Query: 203 KENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRT 262
KENIP+WK SI+VSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKD+
Sbjct: 226 KENIPEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKI 285
Query: 263 AILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTI 322
AILVDDMADTCGTI HAA++L+EAGATKVYAILTHGIFSGPAISRINNAC EAVVVTNTI
Sbjct: 286 AILVDDMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTI 345
Query: 323 PQERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSYLFSNVPY 365
PQ+ HM++CPKIQCIDVSMM AEAVRRTHNGESVSYLFSNVPY
Sbjct: 346 PQDGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSNVPY 388
>UniRef50_P60891 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=156; Eukaryota|Rep: Ribose-phosphate pyrophosphokinase
1 - Homo sapiens (Human)
Length = 318
Score = 584 bits (1443), Expect = e-166
Identities = 278/317 (87%), Positives = 299/317 (94%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
MPNIK+FSGSSH DL+QKI DRLG++LGKVVTKKFSN ETCVEIGESVRGEDVYIVQSG
Sbjct: 1 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPI+AKLVAN+LSV+G
Sbjct: 61 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG 120
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
ADHIITMDLHASQIQGFFDIPVDNL+AEPAVLKWI+ENI +W+ +VSPDAGGAKRVTS
Sbjct: 121 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS 180
Query: 228 IADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAG 287
IADRLNV+FALIHKERKKANEV MVLVGDVKDR AILVDDMADTCGTICHAA+KL+ AG
Sbjct: 181 IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG 240
Query: 288 ATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAV 347
AT+VYAILTHGIFSGPAISRINNAC EAVVVTNTIPQE M+ C KIQ ID+SM+LAEA+
Sbjct: 241 ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI 300
Query: 348 RRTHNGESVSYLFSNVP 364
RRTHNGESVSYLFS+VP
Sbjct: 301 RRTHNGESVSYLFSHVP 317
>UniRef50_UPI000156094F Cluster: PREDICTED: similar to PRPS2
protein; n=2; Mammalia|Rep: PREDICTED: similar to PRPS2
protein - Equus caballus
Length = 301
Score = 510 bits (1259), Expect = e-143
Identities = 245/281 (87%), Positives = 263/281 (93%)
Query: 84 NMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYAR 143
N +T VEIGESVRGEDVYI+QSG GEINDNLMELLIMINACKIAS+SRVTAVIPCFPYAR
Sbjct: 20 NGKTLVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYAR 79
Query: 144 QDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIK 203
QDKKDKSRAPI+AKLVAN+LSV+GADHIITMDLHASQIQGFFDIPVDNL+AEPAVL+WI+
Sbjct: 80 QDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIR 139
Query: 204 ENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTA 263
ENI WK I+VSPDAGGAKRVTSIADRLNV+FALIHKERKKANEV MVLVGDVKDR A
Sbjct: 140 ENIAQWKNCIIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVA 199
Query: 264 ILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIP 323
ILVDDMADTCGTICHAA+KL+ AGATKVYAILTHGIFSGPAISRINNA EAVVVTNTIP
Sbjct: 200 ILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIP 259
Query: 324 QERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSYLFSNVP 364
QE M+ C KIQ ID+SM+LAEA+RRTHNGESVSYLFS+VP
Sbjct: 260 QEDKMRHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVP 300
>UniRef50_Q4P1D3 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Ustilago maydis|Rep: Ribose-phosphate pyrophosphokinase
- Ustilago maydis (Smut fungus)
Length = 432
Score = 402 bits (991), Expect = e-111
Identities = 200/324 (61%), Positives = 251/324 (77%), Gaps = 10/324 (3%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSG---- 106
IKVFSG+SHP+LA+ I RLG LGK + + E+ V I ESVR DVYI+ +
Sbjct: 8 IKVFSGTSHPELAELIAKRLGQPLGKATVTRNESGESIVRIAESVREHDVYIINTSCVSP 67
Query: 107 -----SGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVAN 161
+ N +LMELLIMI+ACK ASA R+TAVIP F YARQDKKDKSRAPITAKL+AN
Sbjct: 68 TPTGAAASPNTSLMELLIMIHACKTASAKRITAVIPHFFYARQDKKDKSRAPITAKLIAN 127
Query: 162 ILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGG 221
+L +G DH+ITMDLHASQIQGFFD+PVDNL+AEPA L++I+E + D +++VSPDAGG
Sbjct: 128 MLENAGCDHVITMDLHASQIQGFFDVPVDNLYAEPAALQYIREMV-DVNKAVIVSPDAGG 186
Query: 222 AKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAE 281
AKR TS+ADRL ++FAL HKERK+ANEV+ MVLVG+V+ + AILVDDMADTCGT+ AA
Sbjct: 187 AKRATSLADRLELDFALFHKERKRANEVSRMVLVGNVEGKVAILVDDMADTCGTLELAAS 246
Query: 282 KLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSM 341
+LIE GA +V AI+THGI SGPA+ RI+N+ LE ++VTNT+PQ + C KI+ ID+S
Sbjct: 247 QLIEYGAERVLAIVTHGILSGPALDRISNSRLEKLIVTNTLPQSHNRSRCTKIEEIDISH 306
Query: 342 MLAEAVRRTHNGESVSYLFSNVPY 365
+LAE +RR+H GESVS LF+ +PY
Sbjct: 307 VLAETIRRSHYGESVSVLFNQIPY 330
>UniRef50_UPI0000EB04C8 Cluster: UPI0000EB04C8 related cluster; n=1;
Canis lupus familiaris|Rep: UPI0000EB04C8 UniRef100
entry - Canis familiaris
Length = 298
Score = 345 bits (847), Expect = 1e-93
Identities = 186/318 (58%), Positives = 231/318 (72%), Gaps = 24/318 (7%)
Query: 48 MPNIKVFSGSSHPDLAQK-IVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSG 106
+P+I +FS S H DL+Q+ + D + ++L KVVTKKFSN ET +E+ + +G+DVY +QSG
Sbjct: 1 VPDIMLFSSSLHQDLSQQDLADLMSLELSKVVTKKFSNQETSLEVSGNRKGKDVYNIQSG 60
Query: 107 SGEINDNLMELLIMINACKIASASRVTAVIPCFPYA-RQDKKDKSRAPITAKLVANILSV 165
GEI +NLM L IMIN KI ++SRVT+VIPCFPY+ + DKKDKS A I+AK VAN+L
Sbjct: 61 YGEIKNNLMGLFIMINTDKITASSRVTSVIPCFPYSDKMDKKDKSHALISAKPVANML-- 118
Query: 166 SGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRV 225
+GADHIITMDLH SQ+QGFF+IPVDNL EPA+L ENI W+ I++
Sbjct: 119 AGADHIITMDLHDSQVQGFFNIPVDNLSVEPAIL----ENIAKWRNCIII---------Y 165
Query: 226 TSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIE 285
ADR+N+EF+ IHKERKKANEV MVLV +KD AIL++DMAD C T CHA
Sbjct: 166 LITADRVNMEFSFIHKERKKANEVDWMVLVSGMKDHMAILMEDMADMCSTTCHA------ 219
Query: 286 AGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAE 345
AGATK YAILTHGIFSGPA SR+ NA EA VVT++I Q M+ C KIQ ID+ M+LA+
Sbjct: 220 AGATKAYAILTHGIFSGPATSRM-NAAFEAGVVTDSILQGDKMRHCSKIQVIDILMILAK 278
Query: 346 AVRRTHNGESVSYLFSNV 363
A+ R HNGESV YLFS +
Sbjct: 279 AIPRKHNGESVFYLFSYI 296
>UniRef50_A7M6E2 Cluster: Ribose-phosphate pyrophosphokinase I; n=1;
Dugesia ryukyuensis|Rep: Ribose-phosphate
pyrophosphokinase I - Dugesia ryukyuensis
Length = 316
Score = 341 bits (837), Expect = 2e-92
Identities = 163/316 (51%), Positives = 236/316 (74%), Gaps = 2/316 (0%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M NI++FSGSS+ L +KI +R+GI L + + KFSN ET V+I ESVRG+DV+I+QSG
Sbjct: 1 MLNIRLFSGSSNILLTEKIGERIGIKLSEAILNKFSNNETSVQIKESVRGKDVFILQSGY 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
++N++LMELLIMINACK AS++R+TAV+P PY+RQ KKD +R PITAKLVA++L ++G
Sbjct: 61 IDVNNHLMELLIMINACKNASSARITAVLPYMPYSRQSKKDNNRVPITAKLVADLLHIAG 120
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
A+HIITMDLHASQIQGFF++PVDNL +E + WIK+NI W+ + S + A+RV +
Sbjct: 121 ANHIITMDLHASQIQGFFNVPVDNLLSESCHISWIKKNISKWEEITIFSLNVTSAERVAN 180
Query: 228 IADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAG 287
+A+ L V F LI+ E+K+A+E ++LVGDV R A+++ D+ D C + + ++L E G
Sbjct: 181 MANTLKVRFGLIYVEKKEASE--QIILVGDVVSRIAVILLDIIDNCDLVISSVKRLKEVG 238
Query: 288 ATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAV 347
A VY I THG+ S + ++++ + +VVTNTI QE+++++ KI C+DVS++ AEA+
Sbjct: 239 AAGVYVIATHGMLSERLMKEVDDSIITKLVVTNTICQEKYVKQSDKIACLDVSVIFAEAI 298
Query: 348 RRTHNGESVSYLFSNV 363
RR H GESVS L++N+
Sbjct: 299 RRIHYGESVSCLYNNL 314
>UniRef50_UPI00005A2C8C Cluster: PREDICTED: similar to
Ribose-phosphate pyrophosphokinase I (Phosphoribosyl
pyrophosphate synthetase I) (PRS-I); n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Ribose-phosphate
pyrophosphokinase I (Phosphoribosyl pyrophosphate
synthetase I) (PRS-I) - Canis familiaris
Length = 339
Score = 325 bits (798), Expect = 1e-87
Identities = 180/314 (57%), Positives = 213/314 (67%), Gaps = 35/314 (11%)
Query: 44 LTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIV 103
L T MP+IK+F GSSH DL+Q+I LG++L ++VTKKFS+ ETCVE+G+S RGED Y V
Sbjct: 39 LLTIMPDIKIFGGSSHQDLSQEIAHHLGLELCRLVTKKFSDQETCVEMGKSERGEDNYTV 98
Query: 104 QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANIL 163
QSG G +D LMELLIMIN CKIASA VTAVIPCFPYARQ KKDKSR
Sbjct: 99 QSGCGHTSDGLMELLIMINTCKIASAHWVTAVIPCFPYARQGKKDKSRG----------- 147
Query: 164 SVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPD--AGG 221
+DLH SQIQGFFDIPVD++ AEPAVLK I+E+I +W+ VVSPD G
Sbjct: 148 -------FTCLDLHTSQIQGFFDIPVDHVRAEPAVLKCIRESISEWRNCTVVSPDRCPWG 200
Query: 222 AKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAE 281
AKRVTS DRLNV+FALIHKE+KKAN + D + ++ T G +
Sbjct: 201 AKRVTSFTDRLNVDFALIHKEQKKANNM-------DFRLTNFSQLEPPEFTHGNLTQ--- 250
Query: 282 KLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSM 341
+T + ILTHGI SGPAI RIN+AC EAVVV N PQE M+ C KIQ ID+SM
Sbjct: 251 -----WSTLTHRILTHGISSGPAIPRINSACFEAVVVMNITPQEEKMKHCSKIQVIDISM 305
Query: 342 MLAEAVRRTHNGES 355
+LAEA+RRTHNGES
Sbjct: 306 ILAEAIRRTHNGES 319
>UniRef50_Q5KCA3 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Filobasidiella neoformans|Rep: Ribose-phosphate
pyrophosphokinase - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 357
Score = 317 bits (778), Expect = 3e-85
Identities = 168/346 (48%), Positives = 243/346 (70%), Gaps = 36/346 (10%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSG- 108
+IK+ +G++HP LA+ + RLGI L KF ++ET V+I SVR EDV+I+QS S
Sbjct: 7 SIKLLTGNAHPKLAEAVAARLGITLTPCHVSKFRSLETSVQIHSSVRDEDVFIIQSPSPP 66
Query: 109 EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGA 168
++ND+LMELLIMI+ACK ASA R+TAVIPC+PYARQDKKDKSRAPIT+KLVAN+L+V+GA
Sbjct: 67 DVNDHLMELLIMISACKTASAKRITAVIPCYPYARQDKKDKSRAPITSKLVANLLAVAGA 126
Query: 169 DHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSI 228
DH+ITMDLHASQIQGFFDIPVDNLF+EP ++++IK IP W+ +I+VSPDAGGAKR T++
Sbjct: 127 DHVITMDLHASQIQGFFDIPVDNLFSEPTMMQYIKSEIPGWRDAIIVSPDAGGAKRATAL 186
Query: 229 ADRLNVEFALIHKERKKANEVASMVL-----------VGDVK----DRTAILVDDM---- 269
AD+LN++FALI+++R++ + ASM L G V D + +V+ M
Sbjct: 187 ADQLNLDFALINRKRRR-DLAASMCLPTVPPTPTGSDSGSVHSHDIDDESNIVEKMELLV 245
Query: 270 ADTCGTICHAAEKLIEAG--------------ATKVYAILTHGIFSGPAISRINNACLEA 315
D G + + +I+ G A +VYA+++HG+ S + +++ ++
Sbjct: 246 GDVKGKVAILIDDMIDTGHTVRLAAGVLRENGAKEVYALVSHGLLSDTTMENLSDLPVKK 305
Query: 316 VVVTNTIPQERHMQEC-PKIQCIDVSMMLAEAVRRTHNGESVSYLF 360
++VTN+I Q + + C ++ +D++ ++AE++RRTHNGES+S LF
Sbjct: 306 LIVTNSIDQTKRVIACNGLLETLDIAPVIAESIRRTHNGESISALF 351
>UniRef50_UPI00015B404E Cluster: PREDICTED: similar to
ENSANGP00000018618; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000018618 - Nasonia
vitripennis
Length = 322
Score = 313 bits (769), Expect = 4e-84
Identities = 155/314 (49%), Positives = 217/314 (69%), Gaps = 3/314 (0%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
+I + +G+SHP+LA I DRLG+ G +N ET VEIG+SVRG+D+YI+Q+G+ +
Sbjct: 8 DIVIIAGNSHPELASLIADRLGVKNGGCAVYYKTNRETMVEIGDSVRGKDIYIIQTGTKD 67
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
+N+N+MELLIM ACK +SA + V+P PY++Q K K R I +KL+A ++ SG
Sbjct: 68 VNNNIMELLIMAYACKTSSAKSIVGVVPYLPYSKQCKMRK-RGCIVSKLLAKMMCKSGLT 126
Query: 170 HIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIA 229
H+ITMDLH +IQGFFD PVDNL A P +L++I+E+IPD++ S++V+ + G AK+ TS A
Sbjct: 127 HLITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDFRNSVIVARNPGSAKKATSYA 186
Query: 230 DRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGAT 289
+RL + A+IH E+ K E + +VGDV R AI+VDDM D + AAE L E GA
Sbjct: 187 ERLRLGIAVIHGEQPK--EKPPINVVGDVGGRIAIMVDDMVDDVQSFVAAAEVLKERGAY 244
Query: 290 KVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRR 349
K+Y + THG+ S A I + ++ VVVTNTIP E +C KI+ +D+S++LAEA+RR
Sbjct: 245 KIYVLATHGLLSSDAPRLIEESPIDEVVVTNTIPHELQKMQCHKIKTVDISILLAEAIRR 304
Query: 350 THNGESVSYLFSNV 363
HN ES+SYLF NV
Sbjct: 305 IHNKESMSYLFKNV 318
>UniRef50_Q75JN8 Cluster: Similar to ribose-phosphate
pyrophosphokinase; n=3; Dictyostelium discoideum|Rep:
Similar to ribose-phosphate pyrophosphokinase -
Dictyostelium discoideum (Slime mold)
Length = 329
Score = 306 bits (751), Expect = 6e-82
Identities = 150/318 (47%), Positives = 223/318 (70%), Gaps = 13/318 (4%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQ-SGSGEIN 111
+ G++HP L+++I L ++G + KF+N ET V I ESVR D+YIVQ + + +N
Sbjct: 8 ILHGNAHPKLSKEIASCLNTEVGNALVSKFANSETQVIINESVRDVDLYIVQPTCNPSVN 67
Query: 112 DNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHI 171
D LMELL+M++ K ASA R+TAV+P F YARQ KKDKSRAPIT KLVAN++ +G D +
Sbjct: 68 DYLMELLVMVDGAKRASAHRITAVVPFFGYARQSKKDKSRAPITCKLVANMMEAAGIDRV 127
Query: 172 ITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDW---KTSIVVSPDAGGAKRVTSI 228
ITMDLH+SQIQGFF+IPV+N++ EP +K+IK+ + ++VSP GG KR +I
Sbjct: 128 ITMDLHSSQIQGFFNIPVENVYTEPLFVKYIKKKKKTEFLNQEFVIVSPGVGGVKRAKAI 187
Query: 229 ADRLNVEFALIHKERKKAN---------EVASMVLVGDVKDRTAILVDDMADTCGTICHA 279
+D+L E A+IH+ K+ + ++ VLVGDV + AI++DD+ADTC T+ A
Sbjct: 188 SDKLESELAIIHRANKEMSLSLSSSFSFDIEETVLVGDVTGKIAIIIDDIADTCKTLKLA 247
Query: 280 AEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDV 339
++ LI+ GA KVYA++THG+FS AI IN++ + +V+T++IP E + ++CPK++ I +
Sbjct: 248 SKALIKKGAIKVYALVTHGVFSNNAIDIINDSSITELVITDSIPNEHNKEKCPKLKIISI 307
Query: 340 SMMLAEAVRRTHNGESVS 357
+ +L+E +RR H+GESV+
Sbjct: 308 ASVLSETMRRCHHGESVT 325
>UniRef50_Q8R753 Cluster: Ribose-phosphate pyrophosphokinase; n=18;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Thermoanaerobacter tengcongensis
Length = 316
Score = 296 bits (726), Expect = 7e-79
Identities = 150/313 (47%), Positives = 213/313 (68%), Gaps = 4/313 (1%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
++K+F+G+S+P LA +I + LG+ L FS+ E V IGESVRG V+++QS
Sbjct: 7 SLKIFTGNSNPKLASEIAEHLGLKLADSEVGTFSDGEISVRIGESVRGASVFVIQSTCAP 66
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
+N+NLMELLIMI+A K ASA+ + AVIP + YARQD+K K+R PITAKLVA++++ +GA
Sbjct: 67 VNNNLMELLIMIDAFKRASAAEINAVIPYYGYARQDRKAKARDPITAKLVADLITAAGAH 126
Query: 170 HIITMDLHASQIQGFFDIPVDNLFAEPAVLKW-IKENIPDWKTSIVVSPDAGGAKRVTSI 228
++TMDLHA QIQG+F+IPVD+L P + K+ + + + D +VVSPD G R
Sbjct: 127 RVVTMDLHAPQIQGYFNIPVDHLLGGPILAKYFMDKELGD--DVVVVSPDHGSVTRARYF 184
Query: 229 ADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA 288
A++LN A+I K R KAN M ++GDVK + AILVDD+ DT GT+ AAE L++ GA
Sbjct: 185 AEKLNAPLAIIDKRRPKANVAEVMNIIGDVKGKKAILVDDLIDTAGTLVQAAEALLDHGA 244
Query: 289 TKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVR 348
++YA THG+ SGPAI R+ + ++ VV+T+TIP ++ KI+ V+ + AEA+
Sbjct: 245 VEIYACATHGVLSGPAIERLKESPIKEVVITDTIPLPEE-KKIDKIKVRSVAPLFAEAIL 303
Query: 349 RTHNGESVSYLFS 361
R H G SVS LF+
Sbjct: 304 RIHEGMSVSKLFT 316
>UniRef50_Q89DJ1 Cluster: Ribose-phosphate pyrophosphokinase; n=310;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Bradyrhizobium japonicum
Length = 317
Score = 295 bits (723), Expect = 2e-78
Identities = 145/317 (45%), Positives = 218/317 (68%), Gaps = 1/317 (0%)
Query: 44 LTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIV 103
++ + +IK+ +G+S+P LAQ I L + L K V ++F++ME VEI E+VRG D +I+
Sbjct: 1 MSAKNGSIKLVAGNSNPALAQAIAQGLHLPLTKAVVRRFADMEIFVEIQENVRGSDAFII 60
Query: 104 QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANIL 163
QS S ND+LMELLI+ +A + +SA R+TAV+P F YARQD+K SR PI+AKLVAN++
Sbjct: 61 QSTSFPANDHLMELLIITDALRRSSARRITAVLPYFGYARQDRKSGSRTPISAKLVANLI 120
Query: 164 SVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAK 223
+ +G D ++T+DLHA QIQGFFDIP DNL+A P +++ IK+ D ++V+SPD GG
Sbjct: 121 TQAGVDRVMTLDLHAGQIQGFFDIPTDNLYAAPLMVRDIKDKF-DLSKTMVISPDVGGVA 179
Query: 224 RVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKL 283
R +A R+N A++ K R++ E M ++GDV T ILVDD+ D+ GT+ +AA+ L
Sbjct: 180 RARGLAKRINTPLAIVDKRRERPGESEVMNVIGDVAGYTCILVDDIVDSGGTLVNAADAL 239
Query: 284 IEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMML 343
I GA VYA +THG+ SG A +RI N+ L+ +V+T++I + + P I+ + ++ ++
Sbjct: 240 IAKGAKDVYAYITHGVLSGGAAARITNSKLKELVITDSILPTDAVSKAPNIRTLPIASLI 299
Query: 344 AEAVRRTHNGESVSYLF 360
++A+ RT ESVS LF
Sbjct: 300 SDAIARTAAEESVSSLF 316
>UniRef50_Q88Z84 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=77; Bacteria|Rep: Ribose-phosphate pyrophosphokinase 1
- Lactobacillus plantarum
Length = 326
Score = 292 bits (717), Expect = 8e-78
Identities = 146/314 (46%), Positives = 210/314 (66%), Gaps = 2/314 (0%)
Query: 49 PNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSG 108
P +K+F+ +S+ LA+KI D +G+ LGK +FS+ E + I ES+RG+ VYI+QS S
Sbjct: 8 PKLKIFALNSNKPLAEKIADAVGVKLGKTSVDRFSDGEIRINIEESIRGDQVYIIQSTSA 67
Query: 109 EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGA 168
+NDNLMELLIMI+A + ASA + VIP + YARQD+K +SR PITAKLVAN+L +GA
Sbjct: 68 PVNDNLMELLIMIDALRRASAKTINVVIPYYGYARQDRKARSREPITAKLVANMLETAGA 127
Query: 169 DHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSI 228
I+ +DLHA+QIQGFFDIP+D+L P + + + D + ++VVSPD GG R +
Sbjct: 128 TRILALDLHAAQIQGFFDIPLDHLMGAPLLADYFLNHHLD-ENAVVVSPDHGGVTRARKL 186
Query: 229 ADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA 288
A+ L A+I K R +AN M ++GDVK + AI++DDM DT GTI A+ L++AGA
Sbjct: 187 AEFLKAPIAIIDKRRPRANVAEVMNIIGDVKGKRAIMIDDMIDTAGTITLGAQALVDAGA 246
Query: 289 TKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVR 348
T+VYA TH + SGPAI RI + ++ +VVT++I + + KI+ + V ++ +A++
Sbjct: 247 TEVYASCTHPVLSGPAIERIEKSPIKKLVVTDSI-ELPAAKRIDKIEQVSVGQLMGQAIK 305
Query: 349 RTHNGESVSYLFSN 362
H + VS LF N
Sbjct: 306 FIHENKPVSPLFKN 319
>UniRef50_Q1GEV9 Cluster: Ribose-phosphate pyrophosphokinase; n=11;
Alphaproteobacteria|Rep: Ribose-phosphate
pyrophosphokinase - Silicibacter sp. (strain TM1040)
Length = 340
Score = 289 bits (708), Expect = 1e-76
Identities = 138/318 (43%), Positives = 217/318 (68%), Gaps = 7/318 (2%)
Query: 52 KVFSGSSHPDLAQKIVDRLGI------DLGKVVTKKFSNMETCVEIGESVRGEDVYIVQS 105
K+ SG+++ LA+ I R+ + DL ++F++ E VE+ E+VRGED++I+Q
Sbjct: 8 KLISGNANLPLAKSISRRMSMHRGVDQDLVNARVERFNDGEIFVEVYENVRGEDMFIIQP 67
Query: 106 GSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSV 165
S NDNLMELLI+ +A + +SA R+TAVIP F YARQD++ K+R PI+AK+VAN+L+
Sbjct: 68 TSNPANDNLMELLIIADALRRSSAQRITAVIPYFGYARQDRRTKARTPISAKMVANMLTG 127
Query: 166 SGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSI-VVSPDAGGAKR 224
+G + ++TMDLHA+QIQGFFDIPVDNL+A P +K D + VVSPD GG R
Sbjct: 128 AGIERVLTMDLHAAQIQGFFDIPVDNLYASPIFALDVKAQFKDQMDDLMVVSPDVGGVAR 187
Query: 225 VTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLI 284
+A R+N +++ K R+KA E+A M ++GDVKD+ ++VDD+ DT GT+C AA+ L+
Sbjct: 188 ARELAKRINAPLSIVDKRREKAGEIAEMTVIGDVKDKICLIVDDICDTAGTLCKAAQILL 247
Query: 285 EAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLA 344
+ GA +V+A ++HG+ SGPA+ R+ N+ ++++V+T++I + + + P I+ + + +
Sbjct: 248 DNGAKEVHAYISHGVMSGPAVERVTNSVMKSLVLTDSIQPTQPILDAPNIRIVPTAPLFT 307
Query: 345 EAVRRTHNGESVSYLFSN 362
+A+ +G SVS LF +
Sbjct: 308 QAILNIWHGTSVSSLFED 325
>UniRef50_A3ZLP4 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Blastopirellula marina DSM 3645
Length = 328
Score = 288 bits (706), Expect = 2e-76
Identities = 144/318 (45%), Positives = 214/318 (67%), Gaps = 6/318 (1%)
Query: 46 TRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQS 105
++M IK+FSG ++P LA I L I LG++ +F + E +I E VRG DV+++Q
Sbjct: 5 SKMREIKIFSGRANPRLAGDICKFLNIPLGRITLGEFPDGENACKIEEDVRGRDVFLIQP 64
Query: 106 GSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSV 165
+N+N+MELLIMI++C+ ASA R+TAVIP F YARQD+KD+ R PITAKLV+++++
Sbjct: 65 TCPPVNNNIMELLIMIDSCRRASAERITAVIPYFGYARQDRKDEGRVPITAKLVSDVITA 124
Query: 166 SGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKE-NIPDWKTSIVVSPDAGGAKR 224
+GAD ++TMDLHA+QIQGFF++PVD+L+A P + + + NIP+ ++VSPDAG KR
Sbjct: 125 AGADRVLTMDLHAAQIQGFFNVPVDHLYAAPVLNHFFQALNIPE-DELVIVSPDAGSIKR 183
Query: 225 VTSIADRLNVEFALIHKERKKANEVA-SMVLVGDVKDRTAILVDDMADTCGTICHAAEKL 283
S RL A+ K R A++ ++ G V+ RTAI+ DDM T G+IC AA+
Sbjct: 184 AVSHHRRLGGRLAICDKRRHSASDTTQENIIGGPVEGRTAIIFDDMISTAGSICGAAKTT 243
Query: 284 IEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIP-QERHMQECPKIQCIDVSMM 342
EAGA ++Y THG+ G AI+R+ A ++ +++T+TIP Q H+ P + + V+ +
Sbjct: 244 FEAGAKEIYIAATHGVLCGDAIARLQAAPIKEIILTDTIPHQSGHL--LPNTKILTVAPL 301
Query: 343 LAEAVRRTHNGESVSYLF 360
L EA++R HN ES+S +F
Sbjct: 302 LGEAIKRIHNDESISAIF 319
>UniRef50_Q9U465 Cluster: Phosphoribosylpyrophosphate synthetase;
n=11; cellular organisms|Rep:
Phosphoribosylpyrophosphate synthetase - Plasmodium
falciparum
Length = 323
Score = 287 bits (704), Expect = 3e-76
Identities = 147/322 (45%), Positives = 212/322 (65%), Gaps = 10/322 (3%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M N +FSG+S+P L++ + D LG LG+V K+F++ E ++ ES+RG+DVYI+Q
Sbjct: 1 MENAILFSGTSNPLLSKNVADHLGTSLGRVNLKRFADGEVSMQFLESIRGKDVYIIQPTC 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
+N+NL+ELL+MI+ C+ ASA ++TAVIP + YARQD+K SR PI+A VA ++ G
Sbjct: 61 PPVNENLIELLLMISTCRRASAKKITAVIPYYGYARQDRKLSSRVPISAADVARMIEAMG 120
Query: 168 ADHIITMDLHASQIQGFFD--IPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRV 225
D ++ +DLH+ QIQGFF +PVDNL A+ L + + D ++VSPDAGG R
Sbjct: 121 VDRVVAIDLHSGQIQGFFGPRVPVDNLEAQLIGLDYFTKK--DLYKPVIVSPDAGGVYRA 178
Query: 226 TSIADRLN------VEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHA 279
D LN A++ K R K NE+ M LVG+V D I+VDDM DT GT+C A
Sbjct: 179 RKFQDGLNHRGIGDCGIAMLIKPRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSGTLCEA 238
Query: 280 AEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDV 339
A++L + GA +V+A THG+FSGPAI RI + LE VVVT+T+ +++ C KI + V
Sbjct: 239 AKQLKKHGARRVFAFATHGLFSGPAIDRIEKSPLEEVVVTDTVKSNKNIDSCKKITKLSV 298
Query: 340 SMMLAEAVRRTHNGESVSYLFS 361
S+++A+A+RR H ES++ LF+
Sbjct: 299 SVLVADAIRRIHQKESLNDLFN 320
>UniRef50_Q7MT83 Cluster: Ribose-phosphate pyrophosphokinase; n=25;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 313
Score = 283 bits (693), Expect = 7e-75
Identities = 142/311 (45%), Positives = 211/311 (67%), Gaps = 5/311 (1%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
N VFSG++ LA+KI + LG LG++ + F++ E V ES+RG DV++VQS +
Sbjct: 6 NFSVFSGTNSRYLAEKICNSLGCPLGRMNIEHFADGEFAVSYEESIRGRDVFLVQS-TFP 64
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
+DNLMELL+MI+A K ASA +TAVIP F +ARQD+KDK R I AKL+A++LS +G
Sbjct: 65 SSDNLMELLLMIDAAKRASAHYITAVIPYFGWARQDRKDKPRVSIGAKLIADLLSKAGIT 124
Query: 170 HIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIA 229
+ITMDLHA QIQGFFD+PVD+L+ +++I++N+P + +V +PD GG KR S A
Sbjct: 125 RLITMDLHADQIQGFFDVPVDHLYGSTVFMEYIRKNMP-LENLVVATPDVGGTKRANSYA 183
Query: 230 DRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGAT 289
L V + HK R KANE+A M ++GDV+D+ +LVDD+ DT GTI AA+ + E GA
Sbjct: 184 KHLGVPMVICHKSRLKANEIAEMRIIGDVQDKDVLLVDDIVDTAGTITKAADLMKENGAR 243
Query: 290 KVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRR 349
V AI +H + S PA R++ + L+ ++ T++IP + +C K++ + V+ + AEA++R
Sbjct: 244 SVCAIASHAVMSDPASMRVDQSTLKEMIFTDSIP---YPHKCEKVKILSVADLFAEAIKR 300
Query: 350 THNGESVSYLF 360
+ ES++ L+
Sbjct: 301 VCSHESITTLY 311
>UniRef50_P65239 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=143; Bacteria|Rep: Ribose-phosphate pyrophosphokinase
1 - Streptococcus pneumoniae
Length = 322
Score = 282 bits (692), Expect = 9e-75
Identities = 144/315 (45%), Positives = 209/315 (66%), Gaps = 7/315 (2%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
++K+F+ SS+ +LA+++ +GI+LGK ++FS+ E V I ES+RG+ V+I+QS S
Sbjct: 5 DLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGKHVFILQSTSSP 64
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
+NDNL+E+LIM++A K ASA V V+P + YARQD+K ++R PIT+KLVAN+L V+G D
Sbjct: 65 VNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRKARAREPITSKLVANMLEVAGVD 124
Query: 170 HIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIA 229
++T+DLHA+QIQGFFDIPVD+L P + + + +VVSPD GG R +A
Sbjct: 125 RLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERRGMVGSDYVVVSPDHGGVTRARKLA 184
Query: 230 DRLNVEFALIHKERK--KANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAG 287
+ L A+I K R K N M ++G V+ +T IL+DDM DT GTICHAA+ L EAG
Sbjct: 185 EFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGKTCILIDDMIDTAGTICHAADALAEAG 244
Query: 288 ATKVYAILTHGIFSGPAISRINNACLEAVVVTNTI--PQERHMQECPKIQCIDVSMMLAE 345
A +VYA TH + SGPA I + ++ +VV +TI P+ER + KI+ I ++ +L +
Sbjct: 245 AVEVYASCTHPVLSGPATDNIQKSAIKKLVVLDTIYLPEERLID---KIEQISIAHLLGD 301
Query: 346 AVRRTHNGESVSYLF 360
A+ R H +S LF
Sbjct: 302 AIVRIHEKRPLSPLF 316
>UniRef50_Q42581 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=145; cellular organisms|Rep: Ribose-phosphate
pyrophosphokinase 1 - Arabidopsis thaliana (Mouse-ear
cress)
Length = 403
Score = 282 bits (691), Expect = 1e-74
Identities = 143/312 (45%), Positives = 208/312 (66%), Gaps = 4/312 (1%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+K+FSG+++P LAQ+I +G+DLGKV K+F++ E V++ ESVRG DVY+VQ
Sbjct: 93 LKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPT 152
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
N+NLMELLIM++AC+ ASA +VTAVIP F YAR D+K + R I AKLVAN+++ +GAD
Sbjct: 153 NENLMELLIMVDACRRASAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADR 212
Query: 171 IITMDLHASQIQGFFDIPVDNLFAEPAVLKWI-KENIPDWKTSIVVSPDAGGAKRVTSIA 229
++ DLH+ Q G+FDIPVD+++ +P +L ++ ++IP + +VVSPD GG R + A
Sbjct: 213 VLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSIPS-EDLVVVSPDVGGVARARAFA 271
Query: 230 DRL-NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA 288
+L + A++ K R N M L+GDV+ + AI+VDDM DT GTI A L + GA
Sbjct: 272 KKLSDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEGA 331
Query: 289 TKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVR 348
+VYA TH +FS PAI R++ L+ V+VTNT+P P++ + V+ +L E +
Sbjct: 332 REVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLP-VAEKNYFPQLTILSVANLLGETIW 390
Query: 349 RTHNGESVSYLF 360
R H+ SVS +F
Sbjct: 391 RVHDDSSVSSIF 402
>UniRef50_A0VM43 Cluster: Ribose-phosphate pyrophosphokinase; n=20;
Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
Dinoroseobacter shibae DFL 12
Length = 340
Score = 280 bits (686), Expect = 5e-74
Identities = 139/316 (43%), Positives = 213/316 (67%), Gaps = 7/316 (2%)
Query: 52 KVFSGSSHPDLAQKIVDRL----GIDLGKVVTK--KFSNMETCVEIGESVRGEDVYIVQS 105
K+ SG+++ +LA I R+ G+ +G V + +F++ E VE+ E+VRGED++I+QS
Sbjct: 8 KIISGNANQELAHAISRRMSAYRGMTVGLVDARVERFNDGEIFVEVFENVRGEDMFIIQS 67
Query: 106 GSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSV 165
S NDNLMELLIM +A + +SA+R+TA+IP F YARQD++ K+R PITAKLVAN++
Sbjct: 68 TSNPANDNLMELLIMCDALRRSSAARITAIIPYFGYARQDRRTKARTPITAKLVANMMVE 127
Query: 166 SGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSI-VVSPDAGGAKR 224
+G + ++TMDLHA+QIQGFFDIPVDNL+A P + N ++ VVSPD GG R
Sbjct: 128 AGIERVLTMDLHAAQIQGFFDIPVDNLYAAPIFALDVMHNFAGRLDNVTVVSPDVGGVAR 187
Query: 225 VTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLI 284
+A R+ A++ K R + V M ++G+V+ +T I+VDD+ DT GT+C AA+ LI
Sbjct: 188 ARELAQRIGCGLAIVDKRRSQPGVVEEMTVIGEVEGQTCIIVDDICDTAGTLCKAADLLI 247
Query: 285 EAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLA 344
GA++V++ +THG+ SGPA+ RI + ++++V+T++I ++ P I+ + + + A
Sbjct: 248 SEGASEVHSYITHGVLSGPAVERITKSNMKSLVITDSIGATDAVKAAPNIRIVPTAPVFA 307
Query: 345 EAVRRTHNGESVSYLF 360
+A+ NG SVS LF
Sbjct: 308 QAILNIWNGTSVSSLF 323
>UniRef50_A4T068 Cluster: Ribose-phosphate pyrophosphokinase; n=20;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 321
Score = 274 bits (672), Expect = 2e-72
Identities = 145/319 (45%), Positives = 213/319 (66%), Gaps = 3/319 (0%)
Query: 45 TTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQ 104
+T + +F+G+++P LA+ + L + +GK +FS+ E VEI E+VRG++V ++Q
Sbjct: 3 STNADLLTLFTGNANPVLAEAVAKELKLPMGKAFVGRFSDGEIQVEIQENVRGKNVVVIQ 62
Query: 105 SGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKS-RAPITAKLVANIL 163
S ND+LMEL+IMI+A K ASASR+TAVIP F YARQD++ +S R I+A++VAN+L
Sbjct: 63 STCAPTNDSLMELMIMIDALKRASASRITAVIPYFGYARQDRRPRSARVAISARIVANML 122
Query: 164 -SVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGA 222
SV+G + ++TMDLHA QIQGFFDIPVDN++A P +L ++ K I+VSPD GG
Sbjct: 123 QSVAGIERVLTMDLHADQIQGFFDIPVDNIYASPVLLADLQAQKTQ-KDLIIVSPDIGGV 181
Query: 223 KRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEK 282
R ++A +L + A+I K R KAN M L+G+V+ R +++DD+ DT GT+C AAE
Sbjct: 182 VRARAMAKQLGTDLAIIDKRRPKANVSEVMHLIGEVEGRHCVIMDDIIDTGGTLCKAAEA 241
Query: 283 LIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMM 342
L E GA V A TH + SG A++RI + L+ +VVT+TIP + KI+ + V+ +
Sbjct: 242 LKERGAKGVTAYCTHAVLSGGAVARIAASELDELVVTDTIPLTPEAMKVTKIRQLTVAPL 301
Query: 343 LAEAVRRTHNGESVSYLFS 361
LAE + R G+SV +F+
Sbjct: 302 LAETLSRISKGDSVMSMFA 320
>UniRef50_Q4P9A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Ustilago maydis|Rep: Ribose-phosphate pyrophosphokinase
- Ustilago maydis (Smut fungus)
Length = 458
Score = 274 bits (671), Expect = 3e-72
Identities = 126/199 (63%), Positives = 166/199 (83%), Gaps = 3/199 (1%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSG- 108
+IK+ +G+SHP+LAQ++ DRLGI L V KKF++ V IG SVR EDVY++Q+G+
Sbjct: 6 SIKLLTGNSHPELAQQVADRLGIPLTPCVCKKFADQSIDVRIGSSVRDEDVYVLQTGNSP 65
Query: 109 --EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVS 166
+ ND+LMELLI+++ACK ASA R+TAVIP FPY+R DKKDKSRAPITAKLVAN+L+V+
Sbjct: 66 YTDPNDSLMELLILLSACKTASARRITAVIPSFPYSRHDKKDKSRAPITAKLVANMLTVA 125
Query: 167 GADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVT 226
GADH+ITMDLHASQIQGFFDIPVDNL +EP+V +WI+ + +W+ +I+VSPDAGGAKR T
Sbjct: 126 GADHVITMDLHASQIQGFFDIPVDNLTSEPSVARWIRSKVENWREAIIVSPDAGGAKRAT 185
Query: 227 SIADRLNVEFALIHKERKK 245
++AD L V+FALI++ R++
Sbjct: 186 ALADSLGVDFALINRNRRR 204
Score = 109 bits (263), Expect = 8e-23
Identities = 56/109 (51%), Positives = 75/109 (68%), Gaps = 1/109 (0%)
Query: 253 VLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNAC 312
+LVGDVK + AILVDDM DT T+ AA+ L AGA KVYAI+THG+ SG +I +
Sbjct: 342 ILVGDVKGKVAILVDDMVDTGRTLALAAKTLEAAGAAKVYAIITHGLLSGQSIDLLRKLS 401
Query: 313 LEAVVVTNTIPQ-ERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSYLF 360
LE +VVTNTI E+ K++ +DVS ++ E +RR+H+GES+S LF
Sbjct: 402 LERLVVTNTIANTEKAKASEGKLEIMDVSAVIGETIRRSHHGESISQLF 450
>UniRef50_A4EBQ1 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 328
Score = 267 bits (655), Expect = 3e-70
Identities = 142/311 (45%), Positives = 198/311 (63%), Gaps = 5/311 (1%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQS-GSG 108
+I+V+SGSS+ LAQKI + LG++L + K+F+N E E+VRG DV+++QS G
Sbjct: 15 SIRVYSGSSNRPLAQKIAEYLGVELSGLTLKQFANGEIYARYDETVRGADVFLIQSVAGG 74
Query: 109 EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGA 168
+ND LMELLI +A K ASA +TAVI + YARQD+K R PITA+LVAN+L +G
Sbjct: 75 NVNDMLMELLIATDAAKRASARSITAVITHYGYARQDRKAGPREPITARLVANLLERAGV 134
Query: 169 DHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSI 228
D IIT+DLH QIQGFFDIPV++L A P ++ + D +VVSPD G AK +
Sbjct: 135 DRIITLDLHQGQIQGFFDIPVNHLSALPLFGQYYNDMHFDTDNLVVVSPDVGRAKAAKKL 194
Query: 229 ADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA 288
+D L + A+ HK R + N M ++GD+K +T ++ DDM DT GT+C ++L GA
Sbjct: 195 SDMLGCDLAIAHKGRPRHNAAEVMGIIGDIKGKTCVINDDMIDTAGTLCANVKELKAMGA 254
Query: 289 TKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVR 348
+Y THGIFSGPAI R+N+A + VVT+ IP ++ KI+ I V+ A+A+
Sbjct: 255 GDIYVCATHGIFSGPAIERLNDAPIVECVVTDAIP----VEVGGKIKTISVAEEFAQAIS 310
Query: 349 RTHNGESVSYL 359
++ E VS L
Sbjct: 311 AVYHEEPVSTL 321
>UniRef50_Q1AXL6 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 331
Score = 266 bits (653), Expect = 5e-70
Identities = 139/311 (44%), Positives = 198/311 (63%), Gaps = 2/311 (0%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+ +FSG +P+LA++I DRL ++LG V +FSN E ESVRG DV+IVQS +
Sbjct: 15 LMLFSGGGYPELAERIADRLDLELGSVELVQFSNGEVYARYLESVRGSDVFIVQSLCDPV 74
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
N NLMELL+M++A K ASA + AVIP + Y+RQD+K K R PITA+LVA +L V+GAD
Sbjct: 75 NKNLMELLVMVDAAKRASAESIVAVIPWYAYSRQDRKTKPREPITARLVAEMLKVAGADR 134
Query: 171 IITMDLHASQIQGFFDIPVDNLFA-EPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIA 229
I+TMDLH QI+GFF PVD+L A V ++ E + ++VV+PD G K +A
Sbjct: 135 IMTMDLHVGQIEGFFSFPVDHLTAMHTFVDHFVDEGFQNAPDTVVVAPDTGEVKMAKRLA 194
Query: 230 DRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGAT 289
D L + +A+++K R+ E ++G+V R AIL+DD+ D GT+ AAE L+ GAT
Sbjct: 195 DHLGLPWAIVNKIRRGPGESEVTHVIGEVSGRRAILIDDIIDGGGTMVGAAEALLSEGAT 254
Query: 290 KVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRR 349
+VYA TH +FSG A RI + + VVVT+T+P + KI+ + ++ +LA +R
Sbjct: 255 EVYAAATHAVFSGRAYERIEESPIREVVVTDTLPLKPGKPR-SKIRTLTIAPILASTIRN 313
Query: 350 THNGESVSYLF 360
+SVS +F
Sbjct: 314 VFTDDSVSAVF 324
>UniRef50_Q9RUD2 Cluster: Probable ribose-phosphate
pyrophosphokinase; n=7; Bacteria|Rep: Probable
ribose-phosphate pyrophosphokinase - Deinococcus
radiodurans
Length = 320
Score = 264 bits (648), Expect = 2e-69
Identities = 138/320 (43%), Positives = 196/320 (61%), Gaps = 2/320 (0%)
Query: 44 LTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIV 103
+ +R + VFSG S+ LAQ I D LG+ LG+ T+KF+N V ES+R DV+IV
Sbjct: 1 MNSRRSPLLVFSGQSNRPLAQAICDNLGVPLGRSRTEKFTNDNLIVHYEESLREGDVFIV 60
Query: 104 QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANIL 163
Q+ S ++D +MEL++MI+A K ASA RVTAVIP + YAR DKKD R I +LVA++L
Sbjct: 61 QTFSTPVSDAIMELMLMIDAAKSASAGRVTAVIPYYSYARSDKKDSPRISIAGRLVADLL 120
Query: 164 SVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAK 223
+GAD ++TM LH+ Q+ GFF +PVD+L A+ + + K+ +PD +V++PDAG K
Sbjct: 121 QEAGADRVLTMTLHSPQVHGFFKVPVDHLSADVVLSQHFKKCVPDAHNGVVLAPDAGSIK 180
Query: 224 RVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKL 283
R + IA RL+ A+I KER EV L+GDV +T +VDD T G++
Sbjct: 181 RASQIARRLDSGLAMIDKERLSDTEVRPRALIGDVDGKTVFIVDDEISTAGSLVETVSIA 240
Query: 284 IEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNT--IPQERHMQECPKIQCIDVSM 341
GA VY +THG++SGPAI RI + V NT +PQ++ + K+ +DV+
Sbjct: 241 RSMGAKDVYVAVTHGVYSGPAIERIAALDVTQVASCNTVLVPQDKLDRAGGKLAVLDVAP 300
Query: 342 MLAEAVRRTHNGESVSYLFS 361
+ A A+ H G SVS LF+
Sbjct: 301 LFASAIANIHTGASVSTLFT 320
>UniRef50_A4VV92 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Streptococcus suis|Rep: Ribose-phosphate
pyrophosphokinase - Streptococcus suis (strain 05ZYH33)
Length = 333
Score = 264 bits (647), Expect = 2e-69
Identities = 140/311 (45%), Positives = 205/311 (65%), Gaps = 3/311 (0%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
NIK+FS +S+ D+A+KI D GI LGK+ +++FS+ E + I ESVRG DVYI+QS S
Sbjct: 17 NIKLFSLNSNRDIAEKIADSAGIPLGKLSSRQFSDGEIQINIEESVRGVDVYIIQSTSYP 76
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
+N++L ELLIMI+ACK ASA+ +TAVIP F YARQD+ R PITAKLVAN+L +G D
Sbjct: 77 VNNHLWELLIMIDACKRASANTITAVIPYFGYARQDRTASPREPITAKLVANMLVKAGVD 136
Query: 170 HIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIA 229
++T+DLHASQIQGFFDIPVDNL EP + E + ++VSP G KR +IA
Sbjct: 137 RVLTLDLHASQIQGFFDIPVDNLLTEPLFAAYYMEKGLCGEDVVIVSPKNSGIKRARNIA 196
Query: 230 DRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGAT 289
+ LN A+I + +E + ++GDV + AILVDD+ +T T A++ + E GAT
Sbjct: 197 EFLNAPIAIIDYAQDD-SERSEGYIIGDVAGKKAILVDDILNTGRTFSQASKIVQEGGAT 255
Query: 290 KVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRR 349
++YA+ +HG+F+G A ++ A ++ ++VT+++ + Q I + S ++A+A+ R
Sbjct: 256 EIYAVASHGLFAGTAAQLLDEAPIKEILVTDSVASKE--QHPKNIAFLTASDLIADAIHR 313
Query: 350 THNGESVSYLF 360
+ +S LF
Sbjct: 314 IQEHQPLSPLF 324
>UniRef50_Q4Q3Z4 Cluster: Phosphoribosylpyrophosphate synthetase,
putative; n=6; Trypanosomatidae|Rep:
Phosphoribosylpyrophosphate synthetase, putative -
Leishmania major
Length = 356
Score = 259 bits (635), Expect = 7e-68
Identities = 136/330 (41%), Positives = 206/330 (62%), Gaps = 10/330 (3%)
Query: 40 HVLPLTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGED 99
HV P I++ SG+++PDL + L +D + K+F+N E +++ ++VRG+D
Sbjct: 25 HVRPGVETTFRIRLISGTANPDLTDNVAKCLNVDKCRTEIKRFANGELNIKVVDNVRGDD 84
Query: 100 VYIVQSGSG----EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPIT 155
+I+Q +G ++N +MELL++++ K++SA R+TA++P + Y+RQD+K + R PI+
Sbjct: 85 CFIIQPTAGGFDTDVNTAMMELLLLVHTLKLSSAKRITAIVPYYAYSRQDRKSEPRVPIS 144
Query: 156 AKLVANILSVSGADHIITMDLHASQIQGFF-DIPVDNLFAEPAVLKWI-KENIPDWKTSI 213
A VA +L G D ++TMDLH QIQGFF +IPVDNL P ++ ++ D ++
Sbjct: 145 ASAVAQLLQCMGVDRVVTMDLHCGQIQGFFRNIPVDNLLMFPEFATYLTRQPWFDKNQTV 204
Query: 214 VVSPDAGGAKRVTSIADRLNV-EFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADT 272
VVSPDAGG +R +ADR+ I K RK+A +V SM VG+V+ T ++VDDM DT
Sbjct: 205 VVSPDAGGVERANVLADRIGASHIVTILKRRKEAGKVDSMQTVGNVQGYTCVIVDDMVDT 264
Query: 273 CGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNAC--LEAVVVTNTIPQERHMQE 330
GT+C A + L E GAT+V A +HGI + PA RI NAC LE VVV+++I Q +
Sbjct: 265 AGTLCKACDLLKEMGATRVIACASHGILTDPACDRI-NACEALEEVVVSDSIDQRLTTAK 323
Query: 331 CPKIQCIDVSMMLAEAVRRTHNGESVSYLF 360
C K+ + + +LA+AV H S+S LF
Sbjct: 324 CDKLTVLTTAPLLAQAVHSLHTEASLSSLF 353
>UniRef50_A6R925 Cluster: Ribose-phosphate pyrophosphokinase I;
n=20; Pezizomycotina|Rep: Ribose-phosphate
pyrophosphokinase I - Ajellomyces capsulatus NAm1
Length = 456
Score = 259 bits (634), Expect = 9e-68
Identities = 123/207 (59%), Positives = 160/207 (77%), Gaps = 4/207 (1%)
Query: 158 LVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSP 217
LVA++L+ +GADHIITMDLH Q QGFFDIPVDNL+ P + K+I ENIP++K SI+VSP
Sbjct: 247 LVADLLTCAGADHIITMDLHDPQYQGFFDIPVDNLYGRPLLKKYITENIPNYKASIIVSP 306
Query: 218 DAGGAKRVTSIADRLNVEFALIHKERKKAN----EVASMVLVGDVKDRTAILVDDMADTC 273
DAGGAKR T+IAD L ++FALIHKER+ + A+M+LVGDV RTAIL+DD+ADT
Sbjct: 307 DAGGAKRATAIADSLGMDFALIHKERRPTKITDRQNATMMLVGDVNGRTAILIDDLADTS 366
Query: 274 GTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPK 333
TI AA+ L + GA++VYA++THGI SG AI RIN + L+ VVVTNT+ Q+ H CPK
Sbjct: 367 NTITRAAKLLKKEGASRVYALVTHGILSGDAIERINASALDKVVVTNTVAQDEHRTRCPK 426
Query: 334 IQCIDVSMMLAEAVRRTHNGESVSYLF 360
++ ++V + AEA+RR H+GES+S LF
Sbjct: 427 LEVLEVGHVFAEAIRRVHHGESISVLF 453
Score = 126 bits (304), Expect = 9e-28
Identities = 61/95 (64%), Positives = 74/95 (77%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
NI V GSSHP L + I + LGI L V+ KFS ET VEI ESVRG+DVYI+QSG G+
Sbjct: 4 NIIVLGGSSHPHLNKAICEHLGIPLANVLLSKFSVGETRVEINESVRGKDVYIIQSGGGK 63
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQ 144
+ND+LMELL++I+ACK ASA RVTAV+P FPY+RQ
Sbjct: 64 VNDHLMELLVIISACKTASAKRVTAVLPLFPYSRQ 98
>UniRef50_Q6MAT0 Cluster: Probable phosphoribosyl pyrophosphate
synthetase; n=1; Candidatus Protochlamydia amoebophila
UWE25|Rep: Probable phosphoribosyl pyrophosphate
synthetase - Protochlamydia amoebophila (strain UWE25)
Length = 313
Score = 256 bits (627), Expect = 7e-67
Identities = 131/307 (42%), Positives = 197/307 (64%), Gaps = 2/307 (0%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+F+GSSHP LA +I +L I LG++ KF + E V++ ESVRG+D +++QS + + N
Sbjct: 9 LFAGSSHPILATEIAQQLKISLGQMQLSKFPDGEIGVQLLESVRGKDTFVLQSIALDPNF 68
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
LMELLI+++A K ASA + AVIP + Y RQD+KDK ITAKLVAN+L +G I+
Sbjct: 69 YLMELLIIVDALKRASARNIVAVIPYYGYCRQDRKDKFDVSITAKLVANLLVEAGITRIL 128
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
TMDLH Q+QGFFDIPVD+L ++ +++ D SIVV+PD G K + A +L
Sbjct: 129 TMDLHVDQLQGFFDIPVDHLSGRQLLIDELQK--LDLTNSIVVAPDIGSVKTARTFASQL 186
Query: 233 NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVY 292
+V+FA++ K RK A EV L+GDV + +L DD+ T T+ AA+ E GA +++
Sbjct: 187 SVDFAIVDKHRKSAIEVVDYHLIGDVNGKDVLLADDICSTGATLMSAAKACQEKGANRIF 246
Query: 293 AILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRTHN 352
A THG+ ++ +I N+ LE V +TNTIP + ++E K++ + ++ +L A++ +
Sbjct: 247 AAFTHGLLVDDSVKQIENSLLEIVWMTNTIPHTKRLKEASKLKTVSIASLLTHAIQCIVS 306
Query: 353 GESVSYL 359
ES+S L
Sbjct: 307 DESISSL 313
>UniRef50_Q5A4X7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Candida albicans|Rep: Ribose-phosphate pyrophosphokinase
- Candida albicans (Yeast)
Length = 404
Score = 254 bits (622), Expect = 3e-66
Identities = 112/201 (55%), Positives = 155/201 (77%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M K+F GSSHP+L Q + DRLG++ KKFSN ET V+IG SVR EDVYI+QSGS
Sbjct: 1 MRKCKIFVGSSHPELGQLVCDRLGVEPAPCTLKKFSNGETSVQIGVSVRDEDVYIIQSGS 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
IND++MELLI+I+AC+ SA+++TAVIP FPY++Q K K R ITA+++AN+L ++G
Sbjct: 61 PHINDHIMELLILISACRGGSANKITAVIPQFPYSKQSKMKKHRGAITARMLANLLVMAG 120
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
ADH+++MDLHASQ+QGFF PVDNLF P + +WI+ +IPDW+ ++VVS + GG KRVT+
Sbjct: 121 ADHVVSMDLHASQMQGFFSKPVDNLFGAPTLARWIRHHIPDWENAVVVSKNPGGTKRVTA 180
Query: 228 IADRLNVEFALIHKERKKANE 248
+AD L + FA+IH +R++ +
Sbjct: 181 LADSLKINFAMIHTDRRRTQD 201
Score = 94.7 bits (225), Expect = 3e-18
Identities = 51/126 (40%), Positives = 78/126 (61%), Gaps = 4/126 (3%)
Query: 242 ERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKL-IEAGATKVYAILTHGIF 300
E ++E + LVGDVKD+ AI++DDM D + AAE L + GA VY + THG+F
Sbjct: 275 ETTTSSEEKLITLVGDVKDKVAIILDDMIDKPNSFIAAAEHLRLNCGAKAVYVVGTHGVF 334
Query: 301 SGPAISRINNA-CLEAVVVTNTIP--QERHMQECPKIQCIDVSMMLAEAVRRTHNGESVS 357
+ + + ++ C++ +VVTNT P +E+ + K+ IDVS + AE +RR H GES+S
Sbjct: 335 NDKCLKDLTDSKCIDKIVVTNTYPISKEQIEKHKDKLVVIDVSPIFAECIRRDHFGESIS 394
Query: 358 YLFSNV 363
LF ++
Sbjct: 395 VLFDSL 400
>UniRef50_A5V1W5 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Chloroflexi (class)|Rep: Ribose-phosphate
pyrophosphokinase - Roseiflexus sp. RS-1
Length = 327
Score = 250 bits (613), Expect = 3e-65
Identities = 124/323 (38%), Positives = 202/323 (62%), Gaps = 9/323 (2%)
Query: 44 LTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIV 103
+++R +++ SG+ +P LAQ I +RLG+ LG V +F+N V + ESVR +DV+++
Sbjct: 1 MSSRFDELRILSGNGNPALAQAICNRLGVRLGDVTITRFANENIFVRLNESVREKDVFVI 60
Query: 104 QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANIL 163
QS + ++D ++ELLIM++AC+ ASA RVTAV+P + Y R DK+D+ R PITA+L+A+++
Sbjct: 61 QSLASPLSDRILELLIMLDACRRASAGRVTAVVPFYAYGRTDKRDQPRVPITARLLADMI 120
Query: 164 SVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAK 223
V+GA ++T+DLHA QIQGFF IPVD L ++++ ++ W +VVS D G AK
Sbjct: 121 QVAGAQQLVTIDLHAGQIQGFFSIPVDELSCMGLLVRYFRDR--GWDDVVVVSSDIGFAK 178
Query: 224 RVTSIADRLNVEFALIHKERKKANEV------ASMVLVGDVKDRTAILVDDMADTCGTIC 277
R + A++L A++ K + ++ L+GDV + ILVDD +T ++
Sbjct: 179 RARNFAEQLGAPLAIVEKRHTARADTDGEEGGDAVSLIGDVAGKRCILVDDEVNTGRSLI 238
Query: 278 HAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCI 337
+AAE L GA +VYA + H + G R+ N+ + +V T+T+P + P ++ +
Sbjct: 239 NAAELLERRGAREVYAAIVHPVLGGDGAERLRNSAIRELVTTDTLPVPAE-KSWPGLRIL 297
Query: 338 DVSMMLAEAVRRTHNGESVSYLF 360
V+ +LAE ++R H+G SV +F
Sbjct: 298 TVAPLLAEVIQRIHSGVSVHTIF 320
>UniRef50_Q83GR1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Actinomycetales|Rep: Ribose-phosphate pyrophosphokinase
- Tropheryma whipplei (strain Twist) (Whipple's
bacillus)
Length = 348
Score = 248 bits (608), Expect = 1e-64
Identities = 132/318 (41%), Positives = 201/318 (63%), Gaps = 8/318 (2%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M N+ + +G SHPDLA+ + LG+ L + + F+N E SVRG+DV+++Q+G
Sbjct: 31 MRNLVLIAGRSHPDLARATAESLGVGLLQTDIRTFANGEIYTRFNSSVRGKDVFVLQTGC 90
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
+ND L+ELL++I++CK ASA ++AV PC+PY+RQD+K R PI+A+LVA++++ +G
Sbjct: 91 DPVNDGLVELLLLIDSCKRASAKHISAVTPCYPYSRQDRKGYGREPISARLVADLIACAG 150
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
AD IIT+DLHASQIQGFF+ PVD+L PA++K +K D T +VSPD G K
Sbjct: 151 ADRIITVDLHASQIQGFFNGPVDHLTGVPALIKHVKSLRIDNLT--IVSPDIGRVKVADV 208
Query: 228 IADRLNVEFALIHKER--KKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIE 285
+D+LN A+IHK R + N V +VGDV+ R ++VDD+ DT T+ AA L +
Sbjct: 209 WSDKLNAPLAIIHKRRDPRVHNNVTMHEIVGDVRSRVCLVVDDLIDTGDTLAKAAIALKK 268
Query: 286 AGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAE 345
AGA KV A THGIFS P ++ ++ V+VT+++P + +++ + ++ +LA
Sbjct: 269 AGAVKVIAAATHGIFSTPE-RLVSCGEIDHVIVTDSVPASKVFD---RVKTVSIAPLLAC 324
Query: 346 AVRRTHNGESVSYLFSNV 363
A+ S+S + V
Sbjct: 325 AICEVVTEGSISEMLDCV 342
>UniRef50_Q1DW45 Cluster: Ribose-phosphate pyrophosphokinase; n=11;
Ascomycota|Rep: Ribose-phosphate pyrophosphokinase -
Coccidioides immitis
Length = 509
Score = 246 bits (602), Expect = 7e-64
Identities = 111/198 (56%), Positives = 152/198 (76%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M +++FSG+SHP L + I +RLG K +KFSN ETCV IG SVR +DV+IVQSGS
Sbjct: 1 MRGVQIFSGTSHPALTEAICERLGTVPAKCELRKFSNGETCVNIGVSVRNQDVFIVQSGS 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
+IND++MELLIMI+ACK SA +TAV+P FPY+RQ KK R ITA+++AN+LS++G
Sbjct: 61 SKINDSVMELLIMISACKGGSAKSITAVLPYFPYSRQSKKKSHRGAITARMLANLLSIAG 120
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
DH+IT+DLHASQ+QGFF PVDNLFAE + +WI+ N+P W ++VV+ +AGG+KRVTS
Sbjct: 121 VDHVITVDLHASQMQGFFGKPVDNLFAESLIARWIRINVPRWHEAVVVTKNAGGSKRVTS 180
Query: 228 IADRLNVEFALIHKERKK 245
+AD L + F ++ +R++
Sbjct: 181 LADALKLNFGIVTTDRRR 198
Score = 99.5 bits (237), Expect = 1e-19
Identities = 49/120 (40%), Positives = 77/120 (64%), Gaps = 3/120 (2%)
Query: 244 KKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLI-EAGATKVYAILTHGIFSG 302
+ +N ++ LVGDV+D+T +VDDM D G+ AAE ++ + GA KVY I THG+F
Sbjct: 386 QNSNHERTITLVGDVRDKTVFIVDDMIDRAGSWIAAAETVVKKGGANKVYCIATHGLFGE 445
Query: 303 PAISRINNA-CLEAVVVTNTIP-QERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSYLF 360
++ ++ C++ VV+TNT P + + K+ +DVS +L+E++RR H GES+S LF
Sbjct: 446 NSLEQMERCDCIDYVVITNTFPIDPQRARRMKKLVVLDVSALLSESIRRHHYGESISSLF 505
>UniRef50_Q4Q0M2 Cluster: Phosphoribosylpyrophosphate synthetase,
putative; n=6; Trypanosomatidae|Rep:
Phosphoribosylpyrophosphate synthetase, putative -
Leishmania major
Length = 358
Score = 245 bits (600), Expect = 1e-63
Identities = 133/319 (41%), Positives = 196/319 (61%), Gaps = 8/319 (2%)
Query: 46 TRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQ- 104
+R +++V G+++P LA+ + L I + F+N ET V+I ES+RG+D++++Q
Sbjct: 6 SRNGSLRVVHGNANPKLAEDVCRYLNIPVTASRVGSFANGETIVKILESIRGDDIFVIQP 65
Query: 105 ----SGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVA 160
S +N +MELL++I+ K++SA RV AVIP + YARQD+K R PI+A VA
Sbjct: 66 TCSNSAGTNVNQAVMELLLIIHTLKLSSARRVIAVIPHYGYARQDRKHTGRVPISASAVA 125
Query: 161 NILSVSGADHIITMDLHASQIQGFF-DIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDA 219
+++ G + ++TMDLH QIQGFF PV +L +++K+ +VV+PDA
Sbjct: 126 RMVTEMGVNGVVTMDLHCGQIQGFFHGCPVADLSPSSEFAEYVKQKNFTPNNLVVVAPDA 185
Query: 220 GGAKRVTSIADRLNV-EFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICH 278
G R + DR+ I K R AN+V SM LVG+V + I+VDDM DT GT+C
Sbjct: 186 GAVNRARRMCDRIGASRIVTILKRRVVANQVDSMQLVGEVDECVCIIVDDMIDTAGTLCK 245
Query: 279 AAEKLIEAGATKVYAILTHGIFSGPAISRINNA-CLEAVVVTNTIPQERHMQECPKIQCI 337
AAE L E GA +V+A THGIF+ PA R+ L VVVT++IPQE Q+C KI+ I
Sbjct: 246 AAEVLKEYGAKEVHAYATHGIFTDPACERLTQCDALVEVVVTDSIPQEESCQKCKKIKVI 305
Query: 338 DVSMMLAEAVRRTHNGESV 356
++ +LA+A+ R H+ ES+
Sbjct: 306 SIAKLLADAIYRMHSEESL 324
>UniRef50_A5URX1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Roseiflexus sp. RS-1
Length = 315
Score = 243 bits (594), Expect = 7e-63
Identities = 130/309 (42%), Positives = 196/309 (63%), Gaps = 4/309 (1%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+F GS P L + I LG+ G+ +FS V I E+VRG VYIVQS + ND
Sbjct: 8 IFPGSGSPKLTKNICAYLGVTPGQCEVLRFSEGNLFVRILENVRGRHVYIVQSTAYPAND 67
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
N MELL I+A K ASA+ VTAV+P F YA+ DKKD+ R I A++ A+ + +GAD I+
Sbjct: 68 NFMELLFWIDAFKRASAASVTAVVPFFSYAKGDKKDEPRVSIRARVCADAIEAAGADRIV 127
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
MDLHA QIQGFF IPVD+L+A P + +++ + + IVV+PD+G AK+ A L
Sbjct: 128 VMDLHAPQIQGFFKIPVDDLYALPVLCDRVRQ--MNLENLIVVAPDSGFAKKARKYARYL 185
Query: 233 NVEFALIHKERKKANEVASMV-LVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKV 291
V A+ KER +E A +V ++GDV+ +TA++VDD + GT+ AE+L+ GA +V
Sbjct: 186 GVSMAVGDKERVAHDEHAHIVEIIGDVQGKTALIVDDFTISAGTLVEVAEQLLVRGAKEV 245
Query: 292 YAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRTH 351
YA +THG+F+ ++ R+ ++ + + +T+T+ + + + P+I+ + V+ + EA+RR H
Sbjct: 246 YAAVTHGVFARGSMERLADSPIRRLFITDTV-ETQPITLTPQIEVVSVAPLFGEAIRRIH 304
Query: 352 NGESVSYLF 360
ES+S LF
Sbjct: 305 YRESISVLF 313
>UniRef50_A0CY99 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=2; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_31, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 394
Score = 242 bits (592), Expect = 1e-62
Identities = 131/322 (40%), Positives = 199/322 (61%), Gaps = 11/322 (3%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
N + SG+S+ +LA++I + L I LG V +F++ E +++ +++RG+DV+I+QS S
Sbjct: 69 NTIILSGNSNKELAEEIAEYLNIKLGSVTIGRFADGECQIQVLDNIRGKDVFIIQSTSPP 128
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
+NDNLMELL++++A + ASA ++ V+P + YARQD+K R PI+A VA +L G D
Sbjct: 129 VNDNLMELLLLVSALRRASARKIIVVVPYYGYARQDRKCAPRVPISAADVARLLETVGVD 188
Query: 170 HIITMDLHASQIQGFFD--IPVDNLFAEPAVLKWIK-ENIPDWKTSIVVSPDAGGAKRVT 226
+I++DLH QIQGFF +PVDNL A ++ + ++K +VSPDAGG R
Sbjct: 189 RLISVDLHCGQIQGFFGPRVPVDNLEANLVAQNYLSLQKKYEFKDVAIVSPDAGGVYRAK 248
Query: 227 SIADR-------LNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHA 279
++ + A+I K+R+ ++ASM LVG VK + I+VDD+ DT GT+ A
Sbjct: 249 KFQEQFDQHHPGMQSHLAMIIKQREGPGKIASMNLVGQVKGKDCIIVDDIIDTAGTLSEA 308
Query: 280 AEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQEC-PKIQCID 338
A L E GA +V+A TH +FSG A + + L+ ++VTNTIP + + KI +
Sbjct: 309 ARVLKEQGAKRVFAFATHALFSGKAFAHLGAPFLDQIIVTNTIPSKPQEEVLGDKICRLS 368
Query: 339 VSMMLAEAVRRTHNGESVSYLF 360
V+ +LAEA+ R ESVS LF
Sbjct: 369 VAPLLAEAIYRVQKKESVSTLF 390
>UniRef50_P32895 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=11; Ascomycota|Rep: Ribose-phosphate pyrophosphokinase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 427
Score = 241 bits (591), Expect = 2e-62
Identities = 106/204 (51%), Positives = 156/204 (76%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M K+F G+SHP+L + RLGI+ KKF+N ET V+IG SVR EDVY++QSGS
Sbjct: 1 MRKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
IND++MELLI+++AC+ SA ++TAVIP FPY++Q K + R ITA+++AN+L ++G
Sbjct: 61 PSINDDIMELLILVSACRGGSARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAG 120
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
ADH+++MDLHASQ+QGFF PVDNL+ P++ KWI+EN+ D++ ++VVS + GG KRVT+
Sbjct: 121 ADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDYEDAVVVSKNPGGTKRVTA 180
Query: 228 IADRLNVEFALIHKERKKANEVAS 251
+AD L + FA+IH +R+++ ++ S
Sbjct: 181 LADSLKINFAMIHTDRRRSKDLYS 204
Score = 95.9 bits (228), Expect = 1e-18
Identities = 49/115 (42%), Positives = 73/115 (63%), Gaps = 3/115 (2%)
Query: 252 MVLVGDVKDRTAILVDDMADTCGTICHAAEKLIE-AGATKVYAILTHGIFSGPAISRINN 310
+ LVG+V+ R+AI++DDM D G+ AAE L++ GA KVY + THGIF+G + +
Sbjct: 310 ITLVGNVRGRSAIILDDMIDRPGSFISAAEHLVQNCGAKKVYVVATHGIFTGDCLEELEK 369
Query: 311 A-CLEAVVVTNTIP-QERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSYLFSNV 363
+ ++ +VVTNT P + K+ IDVS + AE +RR H GES+S LF ++
Sbjct: 370 SDAIDTIVVTNTYPISGERIAGSKKLVTIDVSPIFAECIRRDHYGESISVLFDSL 424
>UniRef50_A7TNR7 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 433
Score = 239 bits (585), Expect = 8e-62
Identities = 107/204 (52%), Positives = 154/204 (75%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M + KVF G+SHP+L + RLG++ V KKF N ET V+IG SVR EDVY++QS S
Sbjct: 1 MRDYKVFIGNSHPELGNLVCQRLGVEPAPCVLKKFVNGETSVQIGVSVRDEDVYVIQSSS 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
+ND++MELLIM++A SA +VTAVIP FPY++Q K K R ITA+++AN+L ++G
Sbjct: 61 NTLNDHIMELLIMVSAFSGGSAGKVTAVIPMFPYSKQSKMKKHRGAITARMLANLLIMAG 120
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
ADH+I+MDLH+SQ+QGFF PVDNL+ P++ +WIKEN+ D++ ++VVS + GG KRVT+
Sbjct: 121 ADHVISMDLHSSQMQGFFSKPVDNLYGGPSLARWIKENVEDYENAVVVSKNPGGTKRVTA 180
Query: 228 IADRLNVEFALIHKERKKANEVAS 251
+AD L + FA+IH +R+++ ++ S
Sbjct: 181 LADSLKINFAMIHTDRRRSKDLYS 204
Score = 97.1 bits (231), Expect = 6e-19
Identities = 48/115 (41%), Positives = 75/115 (65%), Gaps = 3/115 (2%)
Query: 252 MVLVGDVKDRTAILVDDMADTCGTICHAAEKLIE-AGATKVYAILTHGIFSGPAISRINN 310
+ LVG V++ +AI++DDM D + AAE L++ GA KVY I THG+F G + ++
Sbjct: 316 ITLVGSVENSSAIILDDMIDRPTSFVSAAEHLVQNCGAKKVYVIATHGVFIGDCLQQLEQ 375
Query: 311 A-CLEAVVVTNTIP-QERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSYLFSNV 363
+ + +VVTN+ P + H++ K++ IDVS + AE +RR HNGES+S LF ++
Sbjct: 376 SEAIHKIVVTNSYPIPKEHIEMSTKLEVIDVSAIFAECIRRDHNGESISVLFDSL 430
>UniRef50_Q8G5P2 Cluster: Ribose-phosphate pyrophosphokinase; n=56;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Bifidobacterium longum
Length = 340
Score = 239 bits (584), Expect = 1e-61
Identities = 130/319 (40%), Positives = 190/319 (59%), Gaps = 5/319 (1%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
N+ + +G HP LA+ + ++LGID+ + F+N E V ESVRG DV+++QS
Sbjct: 13 NLILVTGRIHPKLAEDVAEQLGIDVLETTAYDFANGEMYVRYTESVRGADVFVLQSHYKP 72
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
IN +ME LIMI+A K ASA +TAV P Y+RQDKK + R PI+ +LV ++L +GAD
Sbjct: 73 INKAIMEQLIMIDALKRASARSITAVCPLLGYSRQDKKHRGREPISCRLVFDLLKTAGAD 132
Query: 170 HIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSI-VVSPDAGGAKRVTSI 228
I+++DLHA+Q QGFFD PVD+L A P ++ +I++ ++ VVSPDAG +
Sbjct: 133 RIMSVDLHAAQSQGFFDGPVDHLVAMPVLVDYIRDRFQGHLDNVAVVSPDAGRIRVAEQW 192
Query: 229 ADRL-NVEFALIHKER--KKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIE 285
A RL A +HK R + N+ + +VGDV + +LVDD+ DT GTI A L +
Sbjct: 193 AQRLGGGPLAFVHKTRDITRPNQAVANRVVGDVAGKDCVLVDDLIDTAGTIAGACHVLQD 252
Query: 286 AGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAE 345
AGA V + THG+ SGPA+ R+ N VV+T+T+P + + + ++ +LA
Sbjct: 253 AGAKSVTVVATHGVLSGPAVERLKNCGAREVVLTDTVPIPEE-KRWDGLTVLSIAPLLAS 311
Query: 346 AVRRTHNGESVSYLFSNVP 364
A+R SV+ LF P
Sbjct: 312 AIRAVFEDGSVAELFDTYP 330
>UniRef50_Q8Y9L8 Cluster: Ribose-phosphate pyrophosphokinase 2;
n=15; Bacilli|Rep: Ribose-phosphate pyrophosphokinase 2
- Listeria monocytogenes
Length = 311
Score = 239 bits (584), Expect = 1e-61
Identities = 127/310 (40%), Positives = 196/310 (63%), Gaps = 3/310 (0%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+K+FS +S LA KI D L I L +V +KFS+ E + I ES+RG + Y+VQS + +
Sbjct: 5 MKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNV 64
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
N+ LMELLIM++A K AS + ++P + YARQD+K +SR PITAKL+AN++ +GA+
Sbjct: 65 NERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANR 124
Query: 171 IITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIAD 230
+IT+DLHA+QIQGFF+IP+D+L A P + ++ EN + K +VV+PD G R IAD
Sbjct: 125 LITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGE-KDVVVVAPDHSGVVRARRIAD 183
Query: 231 RLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATK 290
RLN A++++ + + +E M ++GDVK + AI+VDD+ DT +A+ L+E GA +
Sbjct: 184 RLNAPIAILNR-KPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVE 242
Query: 291 VYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRT 350
V A TH + +G A R+ N+ ++ V+ +++I Q K+ I + +L A+
Sbjct: 243 VIACATHSVMAGNATERLQNSNIKEVITSDSIDLPEDKQ-FDKLTTISIGRILGRAIEGV 301
Query: 351 HNGESVSYLF 360
S+ LF
Sbjct: 302 QENRSLHPLF 311
>UniRef50_A1CDQ3 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Pezizomycotina|Rep: Ribose-phosphate pyrophosphokinase -
Aspergillus clavatus
Length = 489
Score = 235 bits (576), Expect = 1e-60
Identities = 111/206 (53%), Positives = 152/206 (73%), Gaps = 1/206 (0%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M +++FSG+SHP LA+ I +RLG + + KF+N ET V+IG SVR +DVYI+QSGS
Sbjct: 1 MRGVQIFSGTSHPVLAETICERLGTLPARALLGKFANGETRVDIGVSVRNQDVYILQSGS 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAV-IPCFPYARQDKKDKSRAPITAKLVANILSVS 166
+IND++MELLIMI+ACK SA +T FPY+RQ KK R ITA+++AN+LSV+
Sbjct: 61 QKINDSVMELLIMISACKGGSAKSITGQWTRYFPYSRQSKKKSHRGAITARMLANLLSVA 120
Query: 167 GADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVT 226
G DH+IT+DLHASQ+QGFF PVDNLFAEP + +WI+ N+P WK ++VVS +AGG KRVT
Sbjct: 121 GVDHVITLDLHASQMQGFFGKPVDNLFAEPFIARWIRMNVPGWKEAVVVSKNAGGTKRVT 180
Query: 227 SIADRLNVEFALIHKERKKANEVASM 252
S+AD L + F ++ +R++ +M
Sbjct: 181 SLADTLKLNFGIVTTDRRRPKTAMAM 206
Score = 107 bits (257), Expect = 4e-22
Identities = 55/119 (46%), Positives = 77/119 (64%), Gaps = 2/119 (1%)
Query: 244 KKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIE-AGATKVYAILTHGIFSG 302
+ A + ++ LVGDV+ RT LVDDM D G+ AAE +++ GA KVY I THG+F G
Sbjct: 367 RSAEQEKTITLVGDVRGRTVFLVDDMIDKSGSWVAAAETVVKRGGAKKVYCIATHGLFGG 426
Query: 303 PAISRINN-ACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSYLF 360
+ ++ A ++ +VVTNT P HM + K+ ID+S +LAE++RR H GESVS LF
Sbjct: 427 ECLEQMEACAAIDYIVVTNTFPITPHMMKSKKLITIDISSLLAESIRRHHYGESVSALF 485
>UniRef50_A7EV32 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 526
Score = 230 bits (563), Expect = 4e-59
Identities = 108/209 (51%), Positives = 151/209 (72%), Gaps = 2/209 (0%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M N +F+GSS P L +I LG+ V +F+N ET V+I S+R +DV++VQSGS
Sbjct: 1 MRNTLIFAGSSCPKLTDQICTNLGMAAAPVELTQFANGETSVKIMTSIREKDVFVVQSGS 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
+IND++MELLIMI+ACK SA+++TAV+P FPY+RQ KK R ITA+++AN+L V+G
Sbjct: 61 SKINDSIMELLIMISACKGGSANKITAVLPYFPYSRQSKKKSHRGAITARMLANLLHVAG 120
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
+H+IT+DLHASQ+QGFF PVDNL AEP + +WI+ N+P+W ++ VS +AGG KRVTS
Sbjct: 121 INHVITVDLHASQMQGFFKCPVDNLHAEPLIARWIRRNVPEWNEAVCVSKNAGGTKRVTS 180
Query: 228 IADRLNVEFALI--HKERKKANEVASMVL 254
+AD L + F ++ K R AN SM++
Sbjct: 181 LADALKLNFGMVTTDKRRTPANMSMSMII 209
Score = 105 bits (253), Expect = 1e-21
Identities = 51/114 (44%), Positives = 77/114 (67%), Gaps = 3/114 (2%)
Query: 252 MVLVGDVKDRTAILVDDMADTCGTICHAAEKLIE-AGATKVYAILTHGIFSGPAISRINN 310
+ LVGDV++RT +VDDM D G+ AAE +++ GA KVY I THG+F G A+ + N
Sbjct: 410 ITLVGDVRNRTVFIVDDMIDKAGSWIAAAETVVKRGGAKKVYCIATHGLFGGNALEELQN 469
Query: 311 A-CLEAVVVTNTIP-QERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSYLFSN 362
C++ +VVTN+ P ++ K+Q +D+S +L+EA+RR H GES+S LF++
Sbjct: 470 CDCIDMIVVTNSFPIPPEKAKDAKKLQILDLSKLLSEAIRRNHYGESISALFTH 523
>UniRef50_P75044 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Mycoplasma|Rep: Ribose-phosphate pyrophosphokinase -
Mycoplasma pneumoniae
Length = 328
Score = 230 bits (563), Expect = 4e-59
Identities = 128/316 (40%), Positives = 187/316 (59%), Gaps = 6/316 (1%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
N VFS S DL +I +L + +G + +F++ ET + ESVR +DV+I QS
Sbjct: 5 NHVVFSLSKTHDLVSRICQKLKMPMGLITHNEFADGETYIRFEESVRNKDVFIFQSTCAP 64
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
+ND+LMELLI I+A K SA +TA++P + YARQD+K R PIT+KLVA++L+ +G
Sbjct: 65 VNDSLMELLIAIDALKRGSAKSITAILPYYGYARQDRKTMGREPITSKLVADLLTTAGVS 124
Query: 170 HIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIA 229
+ D+H+ Q QGFF+IPVD L L E + K +VVSPD GG KR IA
Sbjct: 125 RVALTDIHSDQTQGFFNIPVDTLRTYHVFLTRTVELLGK-KDLVVVSPDYGGVKRARLIA 183
Query: 230 DRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGAT 289
L + A+I K R N S+ ++G+V ++ ++VDDM DT GT+ AA+ L E A
Sbjct: 184 TSLELPLAIIDKRRPAHNVAESINVLGEVANKNCLIVDDMIDTGGTVIAAAKLLREHHAK 243
Query: 290 KVYAILTHGIFSGPAISRINNACLEAVV----VTNTIPQERHMQECPKIQCIDVSMMLAE 345
KV + THG+F+G A R A E +V V+N+IPQ + +CP+ Q ID++ + E
Sbjct: 244 KVCVMATHGLFNGEAPQRFQKAFNEGLVDYLFVSNSIPQTK-FDQCPQFQVIDLAPLFEE 302
Query: 346 AVRRTHNGESVSYLFS 361
+ N S+S +++
Sbjct: 303 VLLCYANNSSISAIYT 318
>UniRef50_Q6F241 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Mollicutes|Rep: Ribose-phosphate pyrophosphokinase -
Mesoplasma florum (Acholeplasma florum)
Length = 347
Score = 230 bits (562), Expect = 5e-59
Identities = 128/330 (38%), Positives = 205/330 (62%), Gaps = 12/330 (3%)
Query: 44 LTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIV 103
+ ++ N+ +F + +LAQ+I D LG+ +V T KF++ E +E +SVRG++++++
Sbjct: 1 MLSKKENVHIFGLTQGVELAQEICDILGVKRKEVKTLKFADGEILIESLDSVRGKEIFVI 60
Query: 104 QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANIL 163
QS S +N+++MELLI I+A K SA ++ VIP + YARQD+K K R PIT+KLVA++L
Sbjct: 61 QSTSTPVNESIMELLIAIDAFKRGSAEKINVVIPYYGYARQDRKAKGRQPITSKLVADLL 120
Query: 164 SVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIP--DWKTS--IVVSPDA 219
+ +GAD ++++D+H+ Q GFFD+P+DN + + I + I +W S I+VSPD
Sbjct: 121 TKAGADRVMSIDIHSPQSMGFFDVPMDNFYTAQTLATEIIDTIELNNWDPSNCILVSPDY 180
Query: 220 GGAKR---VTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTI 276
GG R V S + A+I K R + N+ ++GD+KD+ ++DDM DT GTI
Sbjct: 181 GGMTRVHKVESYTGGVTNGIAVIGKRRPEPNKAEVEFVLGDIKDKHCFIIDDMIDTGGTI 240
Query: 277 CHAAEKLIEAGATKVYAILTHGIFSGPAISR----INNACLEAVVVTNTIPQERHMQECP 332
+AA+ L E GA V+ HG+F+GPA R I +E VVVTNTI Q ++
Sbjct: 241 INAAKALKEQGAKDVHIFACHGLFNGPAKERMEAAIKEKIVEEVVVTNTI-QIADEKKFN 299
Query: 333 KIQCIDVSMMLAEAVRRTHNGESVSYLFSN 362
++ I V+ +LAE + + + ES++ +++N
Sbjct: 300 GLKIISVAPLLAEMIDSSISHESLTEVYNN 329
>UniRef50_Q4QI56 Cluster: Phosphoribosylpyrophosphate synthetase;
n=8; Trypanosomatidae|Rep: Phosphoribosylpyrophosphate
synthetase - Leishmania major
Length = 370
Score = 230 bits (562), Expect = 5e-59
Identities = 132/315 (41%), Positives = 188/315 (59%), Gaps = 10/315 (3%)
Query: 55 SGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSG----EI 110
SG+ + LA+ + +G ++SN E V I E V G DVYI+QS +G +I
Sbjct: 51 SGNGNRPLAEAVALLMGTHTHHTSVTQYSNGEVNVRINECVLGADVYIIQSTTGNEIIDI 110
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
N LMELL++I ++++A VT + P F YARQD+K R PI+A +VA ++ G +
Sbjct: 111 NTALMELLLLIRKMRLSNAKSVTVIAPFFGYARQDRKTSLRGPISASVVARMVVKMGVNR 170
Query: 171 IITMDLHASQIQGFFD-IPVDNLFAEPAVLKWIKENIPDWKTS--IVVSPDAGGAKRVTS 227
+ ++DLH++QIQGFFD IPVDNL +++ + P + +VVSPDAGG +R
Sbjct: 171 LASLDLHSNQIQGFFDNIPVDNLLMAHEFARYLHDQ-PWFNVDQMVVVSPDAGGVERAKQ 229
Query: 228 IADRLNV-EFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEA 286
+AD L V I K R A +V +M VG+V T I+VDDM DT GT+ A E L E
Sbjct: 230 LADILQVGRIVTIVKRRIAAGKVDTMQSVGEVAGFTCIIVDDMIDTGGTLVKACELLKEL 289
Query: 287 GATKVYAILTHGIFSGPAISRINN-ACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAE 345
GA +V A THGI + P RINN + LE +VV+++IPQE H + PK+ + ++ ++A
Sbjct: 290 GAVRVMACCTHGILTNPCSDRINNCSALEQLVVSDSIPQEEHQKAIPKLTVLTIAPLIAA 349
Query: 346 AVRRTHNGESVSYLF 360
+ R N ESVS LF
Sbjct: 350 VIHRYLNEESVSSLF 364
>UniRef50_Q6CG51 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Yarrowia lipolytica|Rep: Ribose-phosphate
pyrophosphokinase - Yarrowia lipolytica (Candida
lipolytica)
Length = 370
Score = 229 bits (561), Expect = 7e-59
Identities = 112/216 (51%), Positives = 154/216 (71%), Gaps = 10/216 (4%)
Query: 158 LVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSP 217
L+A++L+ +GADHIITMDLH Q QGFFDIPVDNL+ +P + +I IP+++ +++VSP
Sbjct: 154 LIASLLTCAGADHIITMDLHDPQFQGFFDIPVDNLYGKPLLQHYISTQIPNYQDAVIVSP 213
Query: 218 DAGGAKRVTSIADRLNVEFALIHKERK---------KANEVASMVLVGDVKDRTAILVDD 268
DAGGAKR T+IAD L ++FALIHKER+ A+ +LVGDV R AIL+DD
Sbjct: 214 DAGGAKRATAIADGLCMDFALIHKERRPTKISGDHIAGKHNATTMLVGDVSGRVAILIDD 273
Query: 269 MADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHM 328
+ DT TI AA+ L + GA KVYA++THG+FSG A+ +I + ++ +V TN+ PQ++H
Sbjct: 274 LLDTSNTITRAAKLLKDQGAVKVYALITHGVFSGDAVEKIKKSEIDKIVTTNSTPQDQHA 333
Query: 329 QEC-PKIQCIDVSMMLAEAVRRTHNGESVSYLFSNV 363
E K+ ID+S + AEA+RR HNGESVS LF +V
Sbjct: 334 VELGEKLDVIDISRVFAEAIRRIHNGESVSMLFDHV 369
Score = 117 bits (281), Expect = 6e-25
Identities = 64/129 (49%), Positives = 79/129 (61%), Gaps = 5/129 (3%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M + +FSGSSHP L ++I L I+ V KF N ET V I +SVR +DVY+VQSG
Sbjct: 1 MRSATIFSGSSHPKLVERICANLAIEPSNVDLAKFKNGETSVTIRDSVREKDVYVVQSGC 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
G +NDN +ELLIMI+ACK ASA +VTAV+P FPY+RQ P T +V G
Sbjct: 61 GHVNDNFIELLIMISACKTASAKKVTAVMPLFPYSRQPD-----VPYTKAIVPPGGKTGG 115
Query: 168 ADHIITMDL 176
D T DL
Sbjct: 116 KDSDSTTDL 124
>UniRef50_Q8X022 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Pezizomycotina|Rep: Ribose-phosphate pyrophosphokinase -
Neurospora crassa
Length = 431
Score = 229 bits (560), Expect = 9e-59
Identities = 113/228 (49%), Positives = 163/228 (71%), Gaps = 24/228 (10%)
Query: 158 LVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSP 217
LVAN+L+ +G DH+ITMDLH Q+QGFFDIPVDNL+ +P + ++I+++IP+W+ ++++SP
Sbjct: 202 LVANLLTCAGCDHVITMDLHDPQVQGFFDIPVDNLYGQPLLKRYIQQHIPNWRDAVIISP 261
Query: 218 DAGGAKRVTSIADRLNVEFALIHK-------------------ERKKA----NEVASMVL 254
DAGGAKR T+IAD L +EFALIHK ER+ + ASM+L
Sbjct: 262 DAGGAKRATAIADSLGMEFALIHKVNALLQISPPGLPLNQESQERRPTKITDRQNASMML 321
Query: 255 VGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLE 314
VG+V DR IL+DD+ADT TI AA+ L + GAT +YA+LTHG+FSG AISR+ + ++
Sbjct: 322 VGNVTDRVCILLDDIADTGNTITRAAKLLKKEGATTIYALLTHGVFSGDAISRVKASAID 381
Query: 315 AVVVTNTIPQERHMQEC-PKIQCIDVSMMLAEAVRRTHNGESVSYLFS 361
+VVTN++PQ+ H ++ K+ +D+S + AEA+RR H+GES+S LF+
Sbjct: 382 KLVVTNSVPQDEHKKQLGSKLDVLDISPIFAEAMRRVHHGESISVLFN 429
Score = 101 bits (242), Expect = 3e-20
Identities = 54/111 (48%), Positives = 74/111 (66%), Gaps = 6/111 (5%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSG- 108
NI V G+SHP+L + I LG+ + KFS+ E+ EI +SVRG+DVYI+Q+G G
Sbjct: 4 NIVVLGGNSHPELVESICGILGLPACSRILTKFSSGESRCEIQDSVRGKDVYIIQTGFGG 63
Query: 109 ---EINDNLMELLIMINACKIASASRVTAVIPCFPYARQD--KKDKSRAPI 154
+ND+ M+L IMI+ACK SA RVTAV+P FPY+RQ +K+ AP+
Sbjct: 64 NGSRLNDHFMDLCIMISACKTGSARRVTAVLPLFPYSRQPDLPYNKAGAPL 114
>UniRef50_Q3M5L4 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Anabaena variabilis ATCC 29413|Rep: Ribose-phosphate
pyrophosphokinase - Anabaena variabilis (strain ATCC
29413 / PCC 7937)
Length = 310
Score = 228 bits (557), Expect = 2e-58
Identities = 116/314 (36%), Positives = 192/314 (61%), Gaps = 5/314 (1%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M N +F+G+++PDLA + +L I LGK ++F + E V + ESVR + V+I+QS +
Sbjct: 1 MDNFILFAGTANPDLAGTVAQKLDIPLGKSAVERFPDGEVNVRLLESVRQKSVFILQSTA 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
+ND+L+ELL +AC+ A+ASR+TA+IP F YAR DK+ R PITA +VA +L G
Sbjct: 61 PPVNDHLVELLAFADACRRAAASRITAIIPYFGYARADKRHGRREPITASMVAEVLQAVG 120
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
+H++T+DLH QI+GFF IPVD+L A P + I+ +P +VVSPD G + T
Sbjct: 121 VNHVVTLDLHTLQIEGFFRIPVDSLTAVPIFCEAIRHYLP--PNFVVVSPDTGRVQMATQ 178
Query: 228 IADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAG 287
A +L+ ++HK R E +VGDVK +++DDM T GT+ + E L++A
Sbjct: 179 YAQKLDSSVVVLHKHRTSGTETEVTRVVGDVKGYACLIIDDMISTGGTLAKSIEALLKAE 238
Query: 288 A-TKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEA 346
A ++ THG+F A +++++ ++A+ VT+++ + + +++ + ++ ++A
Sbjct: 239 ARPEIIIAATHGLFVKEARAKLSHPSVKAIFVTDSVTSKE--TDWQQLKIVSIAPLVATT 296
Query: 347 VRRTHNGESVSYLF 360
++R S+S LF
Sbjct: 297 IQRFKTDGSISDLF 310
>UniRef50_Q8EUI1 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Mycoplasma penetrans|Rep: Ribose-phosphate
pyrophosphokinase - Mycoplasma penetrans
Length = 332
Score = 225 bits (551), Expect = 1e-57
Identities = 125/316 (39%), Positives = 183/316 (57%), Gaps = 6/316 (1%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
N +F S+ A+++ ++ I LG + T KF++ E V+ +VRG V++ QS
Sbjct: 7 NCIIFGLSNGYLYAKEVAEKTNIQLGTIKTSKFADGEILVKSNSTVRGMHVFLFQSTCNP 66
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
+NDNLMELLI I++ K ASA +T +IP F YARQD+K K R PIT KLVAN L +GA
Sbjct: 67 VNDNLMELLIAIDSLKRASAKTITVIIPYFGYARQDRKAKGREPITCKLVANFLEGAGAT 126
Query: 170 HIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPD-WKTSIVVSPDAGGAKRVTSI 228
+I +D+H+ Q QGFFDIPVD L A + ++N P K VV+PD G K V I
Sbjct: 127 KVILIDIHSEQTQGFFDIPVDTLTASCVLFNEFRKNNPSVIKNLTVVAPDYGAVKNVRKI 186
Query: 229 ADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA 288
+ LN+ A++ K R + N V ++GDV R +L+DDM DT GTI E L E G
Sbjct: 187 TETLNLNLAIMDKRRPQPNVVEISNVLGDVMGRDCLLLDDMIDTGGTILQNIELLKERGC 246
Query: 289 TKVYAILTHGIFSGPAISR----INNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLA 344
K++ + THG+FS A+ + ++ ++ + V +TI + E P I+ + +S A
Sbjct: 247 KKIFVMATHGVFSNGALEKFKLALDKGLIDQLYVADTIEANTKI-EHPNIKVVSLSNFYA 305
Query: 345 EAVRRTHNGESVSYLF 360
E + N +SVS ++
Sbjct: 306 EILDAQINHKSVSKIY 321
>UniRef50_A7ARJ1 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=1; Babesia bovis|Rep: Ribose-phosphate
pyrophosphokinase, putative - Babesia bovis
Length = 339
Score = 223 bits (544), Expect = 8e-57
Identities = 126/307 (41%), Positives = 184/307 (59%), Gaps = 13/307 (4%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
N+ VF+G+ + L G+ LGK FS+ E V++ E + G DV I+QS S
Sbjct: 34 NLLVFTGNWNKCLVNDTCSLSGLTLGKSDVSTFSDGEIKVDLQEEILGCDVVIIQSTSPP 93
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
+N NL+ELL MI+A + + A ++TA+IP F YARQD+K + I+A VA +L ++G D
Sbjct: 94 VNRNLIELLFMISAARKSGAKQITAIIPYFGYARQDRKPSPGSNISASDVARMLELTGVD 153
Query: 170 HIITMDLHASQIQGFFD--IPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
+I+ DLH++ QGFF + VDNL +V+K +++ + VVSPDAG R
Sbjct: 154 RVISFDLHSAMCQGFFGPRVQVDNL----SVIKIFIDHLVGFNRVAVVSPDAGAYARSIQ 209
Query: 228 IAD-------RLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAA 280
+ D + +V A+I K+R KANE+AS L GDVKDR I+ DD+ DT GT+C AA
Sbjct: 210 LYDIFTKKYPQCDVSSAMIFKQRLKANELASAQLCGDVKDRDVIIADDIVDTAGTLCKAA 269
Query: 281 EKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVS 340
E LI GA V A++THGIFSGPA+ RI + + ++ T++I + PKIQ I ++
Sbjct: 270 EILITNGAKSVTAVITHGIFSGPALQRIRESPITRILTTDSIAHSESVLAEPKIQIISLA 329
Query: 341 MMLAEAV 347
L+ +
Sbjct: 330 QELSRVL 336
>UniRef50_Q8D2K5 Cluster: PrsA protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
PrsA protein - Wigglesworthia glossinidia brevipalpis
Length = 305
Score = 222 bits (543), Expect = 1e-56
Identities = 120/299 (40%), Positives = 184/299 (61%), Gaps = 4/299 (1%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+K+FSGSS+ L+ KI + LGI + KF + E ++I E+VRGE+V+I+QS +
Sbjct: 1 MKIFSGSSNIKLSNKIANLLGISISNSEINKFQDGEINIKINENVRGEEVFIIQSMCFPV 60
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKK-DKSRAPITAKLVANILSVSGAD 169
NDN MEL+I +A K ASA ++ AVIP Y+RQD++ + PITAK++AN+L+ SG
Sbjct: 61 NDNFMELVITADALKRASAKKIIAVIPYLGYSRQDRRVYNEQVPITAKMIANLLAASGIC 120
Query: 170 HIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIA 229
H+I +DLH QIQGFFDI +D++ E I ++VSPD GG KRV I+
Sbjct: 121 HVIIVDLHCEQIQGFFDIILDSITTENIFFNDIISQ--KLNQPVLVSPDFGGMKRVRRIS 178
Query: 230 DRLN-VEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA 288
LN + +I K R K NE + ++GDV +R IL+DD+ DT T+C +A L + GA
Sbjct: 179 KMLNHKDIVIIEKYRPKLNESEVIKVIGDVNNRDCILLDDIIDTASTLCKSALCLKKLGA 238
Query: 289 TKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAV 347
+K+ TH +FS + I N+ ++ +V ++IP +++ KI+ + +S +LA+ +
Sbjct: 239 SKIICYATHPVFSKKSYKNIKNSEIDEFIVCDSIPLNVNIKCFNKIRVLTISKILADHI 297
>UniRef50_Q03YB5 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Lactobacillales|Rep: Ribose-phosphate pyrophosphokinase
- Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 323
Score = 219 bits (536), Expect = 7e-56
Identities = 113/308 (36%), Positives = 181/308 (58%), Gaps = 1/308 (0%)
Query: 49 PNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSG 108
P ++F+ S+ +LA +I LG+ L + K F++ E I +VRG +VY++Q +
Sbjct: 3 PAYELFNLGSNDELAGEISTILGVPLAPIDIKTFADNEIYERIENTVRGRNVYVIQGITA 62
Query: 109 EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGA 168
+NDN M+L+I I+A + ASA+ + +IP F YAR D+K +SR PI+A+++AN+L G
Sbjct: 63 PVNDNFMKLMIFIDAARRASANSINVIIPYFGYARSDRKARSREPISARMIANMLESQGV 122
Query: 169 DHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSI 228
++TMDLHA Q+QGFFDIPVD+L A PA+ + N +VV+PD R
Sbjct: 123 KRVMTMDLHADQVQGFFDIPVDHLLAMPALGHYFYANDLLGDDLVVVAPDHSSVARARKF 182
Query: 229 ADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA 288
A L+ ++AL+ + + G+V + AIL+DD+ DT ++ A+E AGA
Sbjct: 183 AKLLHADWALVDRRVDSVRPNTPYQITGNVAGKRAILIDDIIDTGTSMVLASEAAANAGA 242
Query: 289 TKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVR 348
++YA+ TH + S A+ + A ++ VVV NT+ H + K++ + V+ AEA+R
Sbjct: 243 IEIYAVATHAVLSDNAVDHLEKAPIDHVVVANTVEIAEH-KNMSKLKVLSVAESFAEAIR 301
Query: 349 RTHNGESV 356
R + ES+
Sbjct: 302 RINVFESI 309
>UniRef50_Q822W0 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Chlamydophila|Rep: Ribose-phosphate pyrophosphokinase -
Chlamydophila caviae
Length = 301
Score = 217 bits (530), Expect = 4e-55
Identities = 121/297 (40%), Positives = 184/297 (61%), Gaps = 8/297 (2%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+ SGSS+ LAQ + L I LG++ +F + ET V++ E VRG DV+I+QS G+ N
Sbjct: 7 LLSGSSNLILAQNVCAELKIKLGRMELNQFPDGETHVKVLEDVRGRDVFIMQSIVGQPNH 66
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
L ELLI+ +A K +SA +TA+IP Y RQD+++K+ PITAKLVA++L+ +G ++I
Sbjct: 67 YLFELLIIADALKRSSAKSITAIIPYLGYCRQDRRNKTGEPITAKLVADVLTTAGITNLI 126
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
T DLHA QI+GF+ VD+L + + IK I + I ++PD G K IA L
Sbjct: 127 TCDLHADQIEGFYKTHVDHLHCQQLFVDTIKSCIS--QDCIAIAPDIGSIKIAERIARML 184
Query: 233 NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVY 292
+ A+I KER + EV SM L+G+V+D+ +++DD+ T T+ AA + GA K+
Sbjct: 185 DTGLAVIKKERLNSFEV-SMQLIGEVQDKNVVIIDDLCSTANTLVEAANLCKQKGAKKII 243
Query: 293 AILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPK-IQCIDVSMMLAEAVR 348
A +THG+F G AI +I + LE++ VT+TI H+Q I+ + + M+A A++
Sbjct: 244 ATVTHGLFVGDAIQKIETSALESLFVTDTI----HLQSTSTCIKTLSTAPMIASAIK 296
>UniRef50_Q74LT0 Cluster: Phosphoribosylpyrophosphate synthetase;
n=5; Lactobacillus|Rep: Phosphoribosylpyrophosphate
synthetase - Lactobacillus johnsonii
Length = 329
Score = 217 bits (530), Expect = 4e-55
Identities = 121/313 (38%), Positives = 188/313 (60%), Gaps = 7/313 (2%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+K+ + LA++I L L + + FS+ E V I ESVRG DVY++QS +
Sbjct: 13 MKLIGLGGNQALAERIAAALDKPLLETAVQHFSDGEIQVNITESVRGCDVYVIQSIQDPV 72
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
N+N MEL+I+++A ASA V VIP Y+RQD K++SR PITAKL+AN+L ++ D
Sbjct: 73 NENFMELMIVLDALHRASAHSVNVVIPYMAYSRQDTKNRSREPITAKLLANLLQLTDIDD 132
Query: 171 IITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTS---IVVSPDAGGAKRVTS 227
+I +DLHASQIQGF++IPVD+L A P + ++ +N K + +VVSPD GAK V +
Sbjct: 133 LIAVDLHASQIQGFYNIPVDHLHAMPILAQYFLDNGIASKENDDVVVVSPDHSGAKLVRT 192
Query: 228 IADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAG 287
+ A++ +R + + ++GDVKD+T I+VDD+ DT I + ++ AG
Sbjct: 193 FGSYFDAPIAIV-DQRGARYDAEAHDMIGDVKDKTVIIVDDLIDTGSRIASSTRSVLAAG 251
Query: 288 ATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAV 347
A KVY TH + S AI +N +E +VVT+TI +H + ++ + V+ +LA+ +
Sbjct: 252 AKKVYVAATHALLSQNAIDVLNELPVEQIVVTDTI---KHKKYPDRMVRLSVARLLAKGI 308
Query: 348 RRTHNGESVSYLF 360
+N +S+ +F
Sbjct: 309 DYIYNDKSIHQIF 321
>UniRef50_Q0G092 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Fulvimarina pelagi HTCC2506|Rep: Ribose-phosphate
pyrophosphokinase - Fulvimarina pelagi HTCC2506
Length = 307
Score = 214 bits (523), Expect = 3e-54
Identities = 108/232 (46%), Positives = 155/232 (66%), Gaps = 2/232 (0%)
Query: 70 LGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASA 129
L + +G+ + ++F++ E VEI E+VRGEDV++VQS S ND+LMELLI+I+A + ASA
Sbjct: 5 LELPVGEALVRRFADQEIFVEIQENVRGEDVFVVQSTSYPANDHLMELLIIIDAMRRASA 64
Query: 130 SRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDIPV 189
R+TAV+P F YARQD+K R PI+AKLVAN+++ +GAD ++T+DLHA QIQGFFDIP
Sbjct: 65 RRITAVLPYFGYARQDRKAGGRTPISAKLVANLITHAGADRVMTLDLHAGQIQGFFDIPT 124
Query: 190 DNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEV 249
DNLFA P + IKE+ D VVSPD GG R ++A RL+ + A++ K R++ E
Sbjct: 125 DNLFAIPLFARDIKEH-QDLSNLTVVSPDVGGVVRARALAKRLDAQLAIVDKRRERPGES 183
Query: 250 ASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFS 301
M ++GDV+ R IL+DD+ D+ + + + +THG+ S
Sbjct: 184 EVMNIIGDVEGRNCILIDDIIDSAARSAMRPQP-SSMPVRERFGYITHGVLS 234
>UniRef50_Q9EWS0 Cluster: Putative ribose-phosphate
pyrophosphokinase; n=9; Actinomycetales|Rep: Putative
ribose-phosphate pyrophosphokinase - Streptomyces
coelicolor
Length = 317
Score = 213 bits (519), Expect = 8e-54
Identities = 119/319 (37%), Positives = 184/319 (57%), Gaps = 6/319 (1%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M +I VFSGS+HPDLA+++ +LG+ L +F+N V++ + R DV++VQ
Sbjct: 1 MRDIAVFSGSAHPDLAEEVCAQLGVPLSPTRVSRFANDCLEVQLMANCRERDVFLVQPLV 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSG 167
+ ++L+ELL+M +A + ASA R+T V+P + YAR DKKD R + +LVA++L +G
Sbjct: 61 TPVQEHLVELLMMCDAARGASAGRITVVMPHYSYARSDKKDAPRISLGGRLVADLLVAAG 120
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
A ++ M LH+ Q+ GFF +PVD+L A + ++ D + VVSPD G AK +
Sbjct: 121 ASRVLAMTLHSPQVHGFFSVPVDHLHALRELAAHFRQY--DLSRATVVSPDLGNAKEAAA 178
Query: 228 IADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAG 287
A L + A K+R + V+ ++GDV R I++DD T+ ++L E+G
Sbjct: 179 FARMLGAQVAAGAKQRYADDRVSISSVIGDVAGRDVIVLDDEIAKGSTVLELLDRLRESG 238
Query: 288 ATKVYAILTHGIFSGPAISRINNA--CLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAE 345
+ THG+F+ A+ R++ LE +V TNT+P K++ + ++ LAE
Sbjct: 239 PRTIRLACTHGLFAAGALGRLSEQPDVLE-IVCTNTVPVPAD-DHTDKLRILSIAPALAE 296
Query: 346 AVRRTHNGESVSYLFSNVP 364
AVRR HNGESVS LF P
Sbjct: 297 AVRRIHNGESVSALFDARP 315
>UniRef50_Q16GA3 Cluster: Ribose-phosphate pyrophosphokinase 1,
putative; n=2; Aedes aegypti|Rep: Ribose-phosphate
pyrophosphokinase 1, putative - Aedes aegypti
(Yellowfever mosquito)
Length = 330
Score = 212 bits (517), Expect = 1e-53
Identities = 101/107 (94%), Positives = 105/107 (98%)
Query: 44 LTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIV 103
L +RMPNIKVFSGSSHPDLA +IVDRLGIDLGKVVTKKFSN+ETCVEIGESVRGEDVYIV
Sbjct: 33 LQSRMPNIKVFSGSSHPDLASRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIV 92
Query: 104 QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKS 150
QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDK+
Sbjct: 93 QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKA 139
>UniRef50_Q9PQV0 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Ureaplasma parvum|Rep: Ribose-phosphate
pyrophosphokinase - Ureaplasma parvum (Ureaplasma
urealyticum biotype 1)
Length = 330
Score = 207 bits (505), Expect = 4e-52
Identities = 118/311 (37%), Positives = 175/311 (56%), Gaps = 1/311 (0%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
+I +FS S+ LA KI + L I+L + KF++ E V VRG V I+QS S
Sbjct: 6 DILLFSLSNSHQLANKIANLLKIELSPIRIDKFADGELIVAPQVPVRGRRVIIIQSTSKP 65
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGAD 169
+ND+LMELLI I++ K ASA ++ VIP + YARQD+K K R PITA+LVA ++ +GA
Sbjct: 66 VNDSLMELLIAIDSIKRASAKAISVVIPYYGYARQDRKAKPREPITARLVAKMIESAGAT 125
Query: 170 HIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIA 229
++T D+H+ Q QGFFDIP D+L A ++K D +VSPD GG KR I+
Sbjct: 126 SVLTWDIHSLQTQGFFDIPFDSLEAVWVLMKHYFSAYKDSSNITIVSPDYGGVKRAREIS 185
Query: 230 DRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGAT 289
A++ K R N+V ++GDVKDR ++VDDM DT GTI AA+ + E GA
Sbjct: 186 IATGATLAIVDKRRSGKNQVEINNVLGDVKDRDCVIVDDMIDTGGTILGAAKIVREKGAK 245
Query: 290 KVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRR 349
+ I THG+F+ A A + ++ I + ++ + ++ +A+ +
Sbjct: 246 SITIIATHGLFNNNARQHFQQAIKDRIINKICIADTIENEPFDGLEIVSIAPAIAKCIEI 305
Query: 350 THNGE-SVSYL 359
G S+S++
Sbjct: 306 YSEGTGSMSFV 316
>UniRef50_O62580 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=2; Giardia intestinalis|Rep: Phosphoribosyl
pyrophosphate synthetase - Giardia lamblia (Giardia
intestinalis)
Length = 370
Score = 205 bits (501), Expect = 1e-51
Identities = 114/282 (40%), Positives = 172/282 (60%), Gaps = 6/282 (2%)
Query: 80 KKFSNMETCVEIGESVRGEDVYIVQS-GSGEINDNLMELLIMINACKIASASRVTAVIPC 138
K+FS+ E ++ ++RG D++IV + NDNLMELL+ I+A K ASA+ VTA+IP
Sbjct: 41 KQFSDGEINLQYESNIRGCDLFIVGAICPPRCNDNLMELLLAIDAAKRASAAHVTAIIPY 100
Query: 139 FPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFF--DIPVDNLFAEP 196
F YARQD+K SR PI+AKLV ++L SG D ++ D+HA+QIQGFF IP D++
Sbjct: 101 FGYARQDRKAASRTPISAKLVTDLLIASGVDRVVVQDIHAAQIQGFFPSSIPFDHIDGYL 160
Query: 197 AVLKWIKENI-PDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLV 255
++ I + D K IVVSPDAGGA R ++A +L+ + A+I K R AN M +V
Sbjct: 161 VFIQAIIDRFEEDIKNLIVVSPDAGGATRCRNLATQLHADIAIIDKRRVVANMCDVMNVV 220
Query: 256 GDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEA 315
GDV + +L DD+ DT ++ AA+ L E GA +V+A +H + SG A +I +C++
Sbjct: 221 GDVNGKICLLYDDIVDTARSLTKAAQALKEKGAEQVFACASHAVLSGEATRKIKESCIDY 280
Query: 316 VVVTNTIP-QERHMQEC-PKIQCIDVSMMLAEAVRRTHNGES 355
++ +++IP + ++E K+Q + M A + H S
Sbjct: 281 ILFSDSIPLSPKQIEELGEKLQIVSGDFMFANCINCIHTDTS 322
>UniRef50_Q6MW31 Cluster: Related to ribose-phosphate
pyrophosphokinase II; n=3; Sordariales|Rep: Related to
ribose-phosphate pyrophosphokinase II - Neurospora
crassa
Length = 501
Score = 201 bits (491), Expect = 2e-50
Identities = 107/231 (46%), Positives = 152/231 (65%), Gaps = 29/231 (12%)
Query: 158 LVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSP 217
L+A++L+ +GAD I+T DLH S QGFFDIPVD+L A P + ++I+ +I ++K +++VSP
Sbjct: 266 LIADLLTCAGADRIVTCDLHESTYQGFFDIPVDHLIARPLLKRYIQHHIENYKEAVIVSP 325
Query: 218 DAGGAKRVTSIADRLNVEFALIHKERKKANEV----ASMVLVGDVKDRTAILVDDMADTC 273
DAGGAKR +IAD L ++FALIHKER++ ++ SM+LVG+V +R ILVDD+ADT
Sbjct: 326 DAGGAKRAAAIADSLGLQFALIHKERRRPSKTHPNYPSMMLVGNVANRICILVDDLADTV 385
Query: 274 GTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQE--- 330
TI AA+ L GA +V A++THG+FSG AI RIN + L+ VVVTNT+ Q RH++
Sbjct: 386 NTITRAAKLLKREGAVQVVALITHGVFSGDAIQRINASALDRVVVTNTVAQHRHLEAFGA 445
Query: 331 ----------------------CPKIQCIDVSMMLAEAVRRTHNGESVSYL 359
C K++ +D++ AEA+RR GES+S L
Sbjct: 446 ARAGGTKEMPDKNKNDVDPRVVCGKLEVLDIAPFFAEAIRRIVFGESISML 496
Score = 57.6 bits (133), Expect = 5e-07
Identities = 29/64 (45%), Positives = 39/64 (60%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGE 109
N+ V SG+SHP + + LGI V +KFS+ ET EI +S+RG+DVYI+QS
Sbjct: 4 NVVVLSGNSHPKFVDSVCNYLGIPPASRVLEKFSSGETRCEIRDSIRGKDVYIIQSFGVG 63
Query: 110 INDN 113
N N
Sbjct: 64 TNRN 67
Score = 54.0 bits (124), Expect = 6e-06
Identities = 24/41 (58%), Positives = 31/41 (75%)
Query: 104 QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQ 144
++G +ND +EL IMI+ACK SA RVTAV+P FPY+RQ
Sbjct: 88 ETGHVTVNDYFIELCIMISACKTGSARRVTAVLPFFPYSRQ 128
>UniRef50_Q98R83 Cluster: Ribose-phosphate pyrophosphokinase; n=10;
Mycoplasma|Rep: Ribose-phosphate pyrophosphokinase -
Mycoplasma pulmonis
Length = 321
Score = 200 bits (487), Expect = 6e-50
Identities = 114/311 (36%), Positives = 189/311 (60%), Gaps = 5/311 (1%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+FS + LAQ+I D L + L V F++ E + E+VR +DV+IV S S N+
Sbjct: 8 IFSMPNTHVLAQEICDELKMKLHSVNKTIFADGEVLLSSKETVRSKDVFIVASTSHPANN 67
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
N+M+LLI +++ K ASA + ++ + YARQD+K + R PI AKL+A++L V+G I+
Sbjct: 68 NIMDLLIFVDSLKRASAKTINVILSYYGYARQDRKAEGRQPIAAKLLADLLQVAGISRIV 127
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
+DLH IQGFF+IPVD++ A+ + K + I D K +I VSPD GG R +A+ +
Sbjct: 128 VVDLHNPSIQGFFNIPVDDIKAQYILSK--EFTIKDEKFTI-VSPDHGGTIRARIMAEII 184
Query: 233 --NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATK 290
+V+ A+I K R N+ + ++GD+ + A++VDD+ DT GTI +AAE L + GA K
Sbjct: 185 SNDVKIAIIDKRRVSTNKTEVLGVIGDINNENAVIVDDIIDTGGTIVNAAEVLKKNGAKK 244
Query: 291 VYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRT 350
+ + +HGIFS + ++ V+VTN+I ++ K++ + ++ L++ +R
Sbjct: 245 ISIVASHGIFSKGFDIFEDADVIDEVIVTNSIDNYELAKKYKKLKIVSLAPFLSKVIRSI 304
Query: 351 HNGESVSYLFS 361
+ +SVS +++
Sbjct: 305 MDSKSVSDIYA 315
>UniRef50_A7HHV4 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Cystobacterineae|Rep: Ribose-phosphate pyrophosphokinase
- Anaeromyxobacter sp. Fw109-5
Length = 311
Score = 192 bits (468), Expect = 1e-47
Identities = 107/310 (34%), Positives = 177/310 (57%), Gaps = 6/310 (1%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
V SGS+HP+L +++ +RLG+ + V ++F + E V + E VRG +VY+VQ S +
Sbjct: 5 VLSGSAHPELTREVAERLGLTSAERVVERFPDGELRVVVKEPVRGAEVYLVQPLSPPADA 64
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
+L+EL+ + +AC+ A A VTAV+P +ARQD++ P A+L A+++S + AD ++
Sbjct: 65 HLLELVFLADACRRAGARSVTAVVPYLAWARQDRRRVEGEPHGARLAADLIS-ARADRVV 123
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
++D+H +GFF +P+D+L A PA+ I ++P + ++VV PD G A+R L
Sbjct: 124 SVDVHGPAAEGFFSVPLDHLTAAPALAAAIARSVP--RDAVVVGPDLGAARRAALFGRLL 181
Query: 233 NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA-TKV 291
+ A++HK R A EV + G+V R ILVDDM T TI A L+ AG ++
Sbjct: 182 GLPSAIVHKARLSAREVEVRGVAGEVAGRAPILVDDMISTGATIEAAVRTLLAAGCRPEI 241
Query: 292 YAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRTH 351
TH +F+ A R+ + +VVT+ +P R +++ + ++ +LAEA+ R
Sbjct: 242 VVAATHPLFTESAPERLARLPIARIVVTDALPVPR--APGLELEVVPLATLLAEAIARLR 299
Query: 352 NGESVSYLFS 361
+ L S
Sbjct: 300 EQRPLGELLS 309
>UniRef50_A0E424 Cluster: Chromosome undetermined scaffold_77, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_77,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 371
Score = 190 bits (463), Expect = 5e-47
Identities = 123/357 (34%), Positives = 193/357 (54%), Gaps = 19/357 (5%)
Query: 15 PLATTSGLVSMKSTITLEDVVNKLDHVLPLTTRMPNIKVFSGSSHPDLAQKIVDRLGIDL 74
P S L+ + ST E+ K+ P VFSG+S+ LA ++ LGI L
Sbjct: 10 PFVCKSSLLQL-STYNREESYTKVYSNQKQYKIEPETIVFSGNSNTKLASEVAKCLGISL 68
Query: 75 GKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTA 134
GKV+ ++F++ E +++ E+VRG + +I+QS +N+NL+EL + I+A + AS +T
Sbjct: 69 GKVLLERFADGECNIQVLENVRGRNAFIIQSTCPPVNENLVELFLFISALRRASVKTITV 128
Query: 135 VIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFF--DIPVDNL 192
+IP + Y+RQD K I A +A IL +G DH++++DLH Q+QG F +PVDNL
Sbjct: 129 IIPYYGYSRQDHKLAKTESIAAADIAKILEQTGIDHLVSIDLHRGQLQGAFSTSVPVDNL 188
Query: 193 FAEPAVLKWIKENIPDWKTS-----IVVSPDAGGAKRVTSIADRL------NVEFALIHK 241
P + + N K S +VSPD G RV + D L N+E A+I+K
Sbjct: 189 --SPYITLIYELNNHPLKLSPPNELTLVSPDFNGVSRVKKVQDELRQELIGNIELAMIYK 246
Query: 242 ERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFS 301
+ +E + LVGDV + ++VDD+ D+ T+ +AA+ L GA V A TH +FS
Sbjct: 247 SKHPVSE-TEISLVGDVNGKNCLIVDDIIDSGRTLKNAADILKREGAKTVMAYGTHPVFS 305
Query: 302 GPAISRINNACLEAVVVTNTIPQERHMQEC--PKIQCIDVSMMLAEAVRRTHNGESV 356
G A + + L + VT+TI + ++ K+ + V+ +LAE + R ES+
Sbjct: 306 GKAALNLGISNLSKIYVTDTIQVKDLDKQILHEKLSVLSVAPLLAETIYRLQKRESL 362
>UniRef50_O60256 Cluster: Phosphoribosyl pyrophosphate
synthetase-associated protein 2; n=62; Eumetazoa|Rep:
Phosphoribosyl pyrophosphate synthetase-associated
protein 2 - Homo sapiens (Human)
Length = 369
Score = 190 bits (462), Expect = 6e-47
Identities = 92/192 (47%), Positives = 136/192 (70%), Gaps = 1/192 (0%)
Query: 55 SGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNL 114
S SS +L++KI +RLG+++GKV + N ET V+I ESVRG+DV+I+Q+ S ++N +
Sbjct: 27 SNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTI 86
Query: 115 MELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITM 174
MELLIM+ ACK + A + VIP FPY++Q K K R I +KL+A+++ +G H+ITM
Sbjct: 87 MELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRK-RGSIVSKLLASMMCKAGLTHLITM 145
Query: 175 DLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNV 234
DLH +IQGFF+IPVDNL A P +L++I+E IPD++ +++V+ AKR S A+RL +
Sbjct: 146 DLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRL 205
Query: 235 EFALIHKERKKA 246
A+IH E + A
Sbjct: 206 GIAVIHGEAQDA 217
Score = 123 bits (296), Expect = 8e-27
Identities = 58/116 (50%), Positives = 79/116 (68%)
Query: 248 EVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISR 307
E + +VGDV R AI+VDD+ D + AAE L E GA K++ + THG+ S A R
Sbjct: 250 EKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRR 309
Query: 308 INNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSYLFSNV 363
I + ++ VVVTNTIP E +CPKI+ +D+SM+L+EA+RR HNGES+SYLF N+
Sbjct: 310 IEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNI 365
>UniRef50_Q2S5C7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Salinibacter ruber DSM 13855|Rep: Ribose-phosphate
pyrophosphokinase - Salinibacter ruber (strain DSM
13855)
Length = 325
Score = 185 bits (450), Expect = 2e-45
Identities = 116/324 (35%), Positives = 170/324 (52%), Gaps = 14/324 (4%)
Query: 48 MPN-IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQS- 105
MP+ +++F+ S + I L +L + F++ E V +VRG DV++VQS
Sbjct: 1 MPDDLRLFALSESRGFGEAIASALDTELDAHHERTFTDGEHEVRPEVNVRGRDVFVVQSL 60
Query: 106 ---GSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANI 162
+ +ND L LL M+ A + ASA RVTAVIP Y R+D+K + R P+T + VA +
Sbjct: 61 YADDTWSVNDKLCRLLFMLGALRDASAERVTAVIPYLCYQRKDRKTRPRGPVTTRYVAGL 120
Query: 163 LSVSGADHIITMDLH-ASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGG 221
G D ++TMD+H + +Q F ++L P + + + + + + VVSPD GG
Sbjct: 121 FEAVGVDRVLTMDVHNLAVLQNAFQARTEHLLGHPLFVHRLTDVVGAEEVA-VVSPDEGG 179
Query: 222 AKRVTSIADRLN------VEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGT 275
KR A+ L V A + K RK + V LVG V+DRTAI+VDDM T GT
Sbjct: 180 VKRAGKFAEGLGAVLNCEVPTAFVEKMRKD-DGVTGGALVGSVEDRTAIVVDDMVSTAGT 238
Query: 276 ICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQ 335
+ A E GA VYA+ THG+F G A R+ A L+A+ VTNT+ ++Q
Sbjct: 239 MTQAIRSCAEEGAESVYAVATHGLFVGEADERLETAPLDALFVTNTVAPRLTGAAAERLQ 298
Query: 336 CIDVSMMLAEAVRRTHNGESVSYL 359
+ + A A++ H SVS L
Sbjct: 299 ICNAAPRFAAAIQAVHTETSVSAL 322
>UniRef50_A3LVW1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Saccharomycetales|Rep: Ribose-phosphate
pyrophosphokinase - Pichia stipitis (Yeast)
Length = 451
Score = 184 bits (449), Expect = 2e-45
Identities = 107/267 (40%), Positives = 158/267 (59%), Gaps = 30/267 (11%)
Query: 126 IASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFF 185
I + S T + P Y + + K L+AN+L +GAD +ITMDLH Q QGFF
Sbjct: 183 IVTNSASTNLPPVDAYGKTESGYKQWIAQNGTLIANLLVTAGADRLITMDLHDPQFQGFF 242
Query: 186 DIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERK- 244
+IPVDNL++ P + +I + IP+++ ++VSPD+GGAKR T++AD + FALIHKER+
Sbjct: 243 NIPVDNLYSRPLLKHYILDYIPNYQECVIVSPDSGGAKRATAVADAIGCSFALIHKERRA 302
Query: 245 -----------KANEV---ASMVLV--GDVKDRTAILVDD-----------MADTCGTIC 277
++ V AS ++ + T +LV D + DT TI
Sbjct: 303 KVAKNPPSTAASSSSVPMSASNTILSSSNTMVATTMLVGDVRDKVCVLIDDLVDTSYTIT 362
Query: 278 HAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQ--ECPKIQ 335
AA+ L + GA VYA++THG+FSG AI+R+N + ++ V+ TN++PQ M+ K +
Sbjct: 363 RAAKLLKDQGAKYVYALVTHGVFSGDAINRVNKSAIDKVITTNSVPQSERMKVLGSDKFE 422
Query: 336 CIDVSMMLAEAVRRTHNGESVSYLFSN 362
+DVS +LAE++RR HNGESVS LF +
Sbjct: 423 VLDVSRILAESIRRIHNGESVSMLFDH 449
Score = 120 bits (288), Expect = 8e-26
Identities = 58/97 (59%), Positives = 74/97 (76%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M ++ V GSSHP L + I L I+ G+V ++KFSN ET +EI +SVR +DV+IVQSG
Sbjct: 1 MRDLVVLGGSSHPSLTRTICRNLTIEQGEVSSRKFSNGETSLEIQDSVREKDVFIVQSGC 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQ 144
G++NDN +ELLIMI ACK ASA RVTAV+P FPY+RQ
Sbjct: 61 GDVNDNFIELLIMIAACKTASAKRVTAVLPLFPYSRQ 97
>UniRef50_Q4UNC9 Cluster: Ribose-phosphate pyrophosphokinase; n=9;
Rickettsia|Rep: Ribose-phosphate pyrophosphokinase -
Rickettsia felis (Rickettsia azadi)
Length = 293
Score = 182 bits (442), Expect = 2e-44
Identities = 105/272 (38%), Positives = 164/272 (60%), Gaps = 5/272 (1%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+K+ +GSS+ LA ++ L I + F++ E VEI ES EDV IVQS S +
Sbjct: 1 MKILAGSSNKLLASRLAIALNIKYIEPRITYFNDSEIKVEIQESFHNEDVIIVQSTSKPV 60
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
ND L+EL ++++A K A A+R+ V+P F YARQD + S+ I AKL+A+ L G +H
Sbjct: 61 NDRLIELFLLVDAAKKAVANRIILVMPYFGYARQDNIN-SQNIIPAKLIADFLEKLGVNH 119
Query: 171 IITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIAD 230
+IT+DLH+ +I+ FF+IP+ NL EP L +I + + ++V+PD G RV I++
Sbjct: 120 VITIDLHSDKIEKFFNIPISNL--EPINL-YIPF-LRTYSNFVIVAPDKGSINRVQKISN 175
Query: 231 RLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATK 290
LN++ A I+KER N + ++G V+ + IL+DD+ D+ TI AA L E A
Sbjct: 176 LLNIDSAYINKERDINNNCEMISIIGSVEGKNCILIDDIIDSGETIVKAARFLKEHSALS 235
Query: 291 VYAILTHGIFSGPAISRINNACLEAVVVTNTI 322
V A +TH + + + +I N+ ++ + VT+TI
Sbjct: 236 VSAFITHAVLATGSKDKIENSVIDKIFVTDTI 267
>UniRef50_A5DKD0 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Saccharomycetaceae|Rep: Ribose-phosphate
pyrophosphokinase - Pichia guilliermondii (Yeast)
(Candida guilliermondii)
Length = 472
Score = 179 bits (436), Expect = 9e-44
Identities = 105/239 (43%), Positives = 146/239 (61%), Gaps = 34/239 (14%)
Query: 158 LVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSP 217
L+AN+L +GAD +TMDLH Q QGFF+IPVDNL+++P + +I + IP+++ ++VSP
Sbjct: 232 LIANLLMTAGADRCVTMDLHDPQFQGFFNIPVDNLYSKPLLKHYIIDYIPNYQQCVIVSP 291
Query: 218 DAGGAKRVTSIADRLNVEFALIHKERK-KANEVASMVLVGDVKDR--------------- 261
D+GGAKR TSIAD + +FALIHKER+ KAN G + R
Sbjct: 292 DSGGAKRATSIADAIGCQFALIHKERRAKANSSGPPSAPGPLGTRSAGGFSSTSSVNNPN 351
Query: 262 ------TAILVDDMAD-----------TCGTICHAAEKLIEAGATKVYAILTHGIFSGPA 304
T +LV D+ D T TI AA+ L + GA VYA++THG+FSG A
Sbjct: 352 GHQLVATTMLVGDVRDRVCVLVDDLVDTSYTITRAAKLLKDQGALYVYALVTHGVFSGDA 411
Query: 305 ISRINNACLEAVVVTNTIPQERHMQEC-PKIQCIDVSMMLAEAVRRTHNGESVSYLFSN 362
I+RI + ++ ++ TN+ PQ+ H + K+ IDVS +LAEA+RR HNGESVS LF +
Sbjct: 412 INRIAKSSIDKLITTNSTPQKTHSEMLGDKLVVIDVSRVLAEAIRRIHNGESVSMLFDH 470
Score = 111 bits (268), Expect = 2e-23
Identities = 56/97 (57%), Positives = 69/97 (71%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M N+ V G+SHPDL + I L + V +FSN ET +EI SVR +DV+I+QSGS
Sbjct: 1 MRNLVVLGGTSHPDLTKSICRILTTEESDVNIGRFSNGETSIEIQGSVRDKDVFIIQSGS 60
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQ 144
G INDN ++LLIMI ACK ASA RVTAV+P FPY+RQ
Sbjct: 61 GHINDNFVQLLIMIAACKTASARRVTAVLPLFPYSRQ 97
>UniRef50_Q5GTH9 Cluster: Phosphoribosylpyrophosphate synthetase;
n=6; Wolbachia|Rep: Phosphoribosylpyrophosphate
synthetase - Wolbachia sp. subsp. Brugia malayi (strain
TRS)
Length = 308
Score = 178 bits (434), Expect = 2e-43
Identities = 100/310 (32%), Positives = 179/310 (57%), Gaps = 20/310 (6%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+K+ G++ +L + I ++L + KF++ E+ ++ ++VYI+QS S +
Sbjct: 1 MKIIIGNASKELGKLIANKLNVQPFSAQVSKFADGAINAEVESNLCSQEVYIIQSISPPV 60
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQD---KKDKSRAPITAKLVANILSVSG 167
ND+LMELL +I+A K + R+T +IP + Y+RQD K + ++ + AKLVAN++ +G
Sbjct: 61 NDHLMELLFIIDAVKRSGTKRITTIIPYYGYSRQDRIIKNNNMQSALNAKLVANLIQTAG 120
Query: 168 ADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIK-ENIPDWKTSIVVSPDAGGAKRVT 226
A + +DLH+SQI+GFFD+P+ NL A I EN+ +V+PD G R
Sbjct: 121 ASSVAVIDLHSSQIEGFFDVPLTNLSCFEAFADSIHIENLA------IVAPDVGAIGRAR 174
Query: 227 SIADRLNVEFAL--------IHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICH 278
+ A L ++ + I K R+KA M ++G+ ++ ++VDD+ D+ GT+C+
Sbjct: 175 AFAKTLEKKYEIKLSDKIIIIDKYREKAGTSHVMNVIGEATNKNCVIVDDIVDSGGTLCN 234
Query: 279 AAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCID 338
AA L A V + +THG+ SG AI +I+++ L+ +V T+TI + +++ KI+ +
Sbjct: 235 AALALKNRRARSVISCITHGVLSGNAIEKISSSSLDKLVTTDTIFHK--LEKTDKIEIVS 292
Query: 339 VSMMLAEAVR 348
++ +L ++
Sbjct: 293 IANILTHFIQ 302
>UniRef50_A4BQ39 Cluster: Ribose-phosphate pyrophosphokinase; n=9;
Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
Nitrococcus mobilis Nb-231
Length = 362
Score = 175 bits (426), Expect = 1e-42
Identities = 112/319 (35%), Positives = 174/319 (54%), Gaps = 13/319 (4%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIV----QSGSG 108
+F+ + + Q++ LG +L + F + E E VRG DVY++ Q S
Sbjct: 38 LFALGATREYGQQVAACLGGELATHEERAFEDGEHKSRPLEGVRGRDVYVLHSLYQDASE 97
Query: 109 EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGA 168
+ND L+ LL + A + A A +TAVIP YAR+D++ K R P+T + VA +L G
Sbjct: 98 GVNDKLVRLLFFLGALRDAHAGCLTAVIPYLAYARKDRRTKPRDPVTTRYVAQLLEAVGV 157
Query: 169 DHIITMDLH-ASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
D ++TMD+H + + F +PV +L A ++ + D + +VVSPDAGG KR
Sbjct: 158 DRVLTMDVHNIAAFENAFRVPVVHLEAGALFVRALCRQAGDSEV-VVVSPDAGGYKRAER 216
Query: 228 IADRLNVEFA----LIHKERKKANEVAS-MVLVGDVKDRTAILVDDMADTCGTICHAAEK 282
+ + L + + L E+K++++V S LVG+V R A++VDD+ T GT+ AA
Sbjct: 217 LRELLAKQRSSSPGLAFMEKKRSDDVVSGEALVGEVSGRVAVIVDDLISTGGTLVKAAMA 276
Query: 283 LIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQEC--PKIQCIDVS 340
+AGA VYA THG+F+G A + A LE + VT+T+P R E ++ + +
Sbjct: 277 CRKAGARAVYAAATHGLFTGAASRVLAGAPLERLFVTDTVPPFRLQAEVLQNRVTLVPTA 336
Query: 341 MMLAEAVRRTHNGESVSYL 359
+L EA+RR H S+S L
Sbjct: 337 PLLGEAIRRLHTDGSLSEL 355
>UniRef50_Q0U4M1 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Phaeosphaeria nodorum|Rep: Ribose-phosphate
pyrophosphokinase - Phaeosphaeria nodorum (Septoria
nodorum)
Length = 464
Score = 171 bits (417), Expect = 2e-41
Identities = 75/132 (56%), Positives = 104/132 (78%)
Query: 115 MELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITM 174
MELLIMI+ACK SA +TAV+P FPY+RQ KK + R ITA++VAN+L V+G +H+IT+
Sbjct: 1 MELLIMISACKGGSAKSITAVMPYFPYSRQSKKKQHRGAITARMVANLLHVAGVNHVITL 60
Query: 175 DLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNV 234
DLHASQ+QGFF PVDNL AEP + +WI+ N+P+W+ ++VVS + GG KRVTS+AD L +
Sbjct: 61 DLHASQMQGFFKCPVDNLVAEPLLSRWIRVNVPNWREAVVVSKNPGGTKRVTSLADALKL 120
Query: 235 EFALIHKERKKA 246
F ++ +R++A
Sbjct: 121 SFGIVTTDRRRA 132
Score = 92.3 bits (219), Expect = 2e-17
Identities = 51/118 (43%), Positives = 75/118 (63%), Gaps = 5/118 (4%)
Query: 248 EVASMV-LVGDVKDRTAILVDDMADTCGTICHAAEKLIE-AGATKVYAILTHGIFSGPAI 305
E+ +MV LVG+VK+R +VDDM D + AAE +++ GATKVY THG+F G +
Sbjct: 343 ELETMVTLVGNVKNRPVFIVDDMMDKSASWIAAAETVVKRGGATKVYCFATHGLFGGDCL 402
Query: 306 SRINNACL-EAVVVTNT--IPQERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSYLF 360
+N L E +++TN IP+ + Q K+ I+V +LAE++RR H+GES+S LF
Sbjct: 403 EEMNKCDLIEKIIITNAFPIPEYKQDQARNKLVVINVDNLLAESIRRNHHGESMSQLF 460
>UniRef50_Q2GIZ1 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Anaplasmataceae|Rep: Ribose-phosphate pyrophosphokinase
- Anaplasma phagocytophilum (strain HZ)
Length = 322
Score = 164 bits (399), Expect = 3e-39
Identities = 101/310 (32%), Positives = 175/310 (56%), Gaps = 18/310 (5%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEI--GESVRGEDVYIVQSGSGEI 110
+ GS+ LA+ + L + + +F++ E +E+ G + + ++QS S
Sbjct: 3 IIPGSTSLALAKSVSGMLDVPMVIPCVSRFADGEINLEVPTGVATGSGHIVLMQSLSAPA 62
Query: 111 NDNLMELLIMINACKIASA-SRVTAVIPCFPYARQDK-------KDKSRAPITAKLVANI 162
+DNL+EL ++ +A + A R+TAVIP Y+RQD+ ++ + ++AK++A I
Sbjct: 63 SDNLIELTLLTDAVRRTLAPQRITAVIPYLCYSRQDRVMQRVDSQETFTSALSAKVIARI 122
Query: 163 LSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGA 222
LS SG DHI+T+DLH+ Q GFFD+P N+ A + ++ + + ++VSPD G
Sbjct: 123 LSTSGLDHIVTLDLHSQQAAGFFDVPFTNISAYDVFVDYLSSSNL-LERLVIVSPDYGAL 181
Query: 223 KRVTS----IADRLN---VEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGT 275
RV + ++ R N ++ A+I K R+ M +VG+V+DR ++DD+ D+ GT
Sbjct: 182 GRVRAFVRMLSSRYNMNSIQVAVIDKYREGPGISEVMHVVGNVQDRHCFILDDIVDSGGT 241
Query: 276 ICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQ 335
+C+AA L GA V++ +THG+ SG AI I A L+++V+T+TI + KI+
Sbjct: 242 LCNAAAALKTRGAISVHSFITHGVLSGRAIDAIGTAELDSLVITDTIHNPDRVNLPEKIK 301
Query: 336 CIDVSMMLAE 345
+ V +L++
Sbjct: 302 VLSVDRLLSD 311
>UniRef50_Q3YQZ8 Cluster: Ribose-phosphate pyrophospho kinase; n=1;
Ehrlichia canis str. Jake|Rep: Ribose-phosphate
pyrophospho kinase - Ehrlichia canis (strain Jake)
Length = 318
Score = 160 bits (389), Expect = 5e-38
Identities = 103/314 (32%), Positives = 170/314 (54%), Gaps = 22/314 (7%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESV--RGEDVYIVQSGSGEI 110
+ SG+S +LA+ I GI L +FS+ E VE+ E+ + + V ++ S
Sbjct: 3 ISSGTSSINLARCISKTTGIKLINTCITRFSDQELNVEVQENQDDKNKHVIVINSLCFPA 62
Query: 111 NDNLMELLIMINACKIASA-SRVTAVIPCFPYARQDKK-----DKSR---APITAKLVAN 161
+DNL+ELL++I+A A S++T ++P Y RQD+ D S + ++AK++ N
Sbjct: 63 HDNLIELLLLIDATNRALCPSKITLIVPYLCYTRQDRVMYRNLDSSSLMVSALSAKVIIN 122
Query: 162 ILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGG 221
L + ++II +DLH++Q+ GFFD + NL + ++ I D ++VSPD G
Sbjct: 123 TLETANINNIIFIDLHSNQLTGFFDTSITNLSSHAIFIEDIAGKY-DMDNLVIVSPDYGA 181
Query: 222 AKRVTSIADRLN--------VEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTC 273
R A+ L+ ++ A+I K R K M + G+V+++ I++DD+ D+
Sbjct: 182 LNRTRVFANALSRQYKLNNEIQVAVIDKYRAKPGVSEVMNIAGNVENKDCIIIDDIVDSA 241
Query: 274 GTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPK 333
GT+C+AA L + GA KV A +THGI SG AI ++ N+ L+ + TNTI PK
Sbjct: 242 GTLCNAASALKDKGALKVSAYVTHGILSGNAIEKVTNSKLDNLTTTNTINHSSF--NTPK 299
Query: 334 IQCIDVSMMLAEAV 347
IQ + + L+ +
Sbjct: 300 IQILSIDKFLSNYI 313
>UniRef50_A2AAG9 Cluster: Likely ortholog of H. sapiens
phosphoribosyl pyrophosphate synthetase- associated
protein 1; n=21; Coelomata|Rep: Likely ortholog of H.
sapiens phosphoribosyl pyrophosphate synthetase-
associated protein 1 - Mus musculus (Mouse)
Length = 175
Score = 154 bits (374), Expect = 3e-36
Identities = 84/178 (47%), Positives = 117/178 (65%), Gaps = 7/178 (3%)
Query: 44 LTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIV 103
+TTR P + P L + RLG +LGK V + +N ET VEI ESVRG+D++I+
Sbjct: 1 MTTRQPEAS--GAAERPILV--LSRRLGAELGKSVVYQETNGETRVEIKESVRGQDIFII 56
Query: 104 QSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANIL 163
Q+ ++N +MELLIM A K A A + VIP FPY++Q K K R I KL+A++L
Sbjct: 57 QTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRK-RGSIVCKLLASML 115
Query: 164 SVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVV--SPDA 219
+ +G HIITMDLH +IQGFF PVDNL A P +L++I+E IP+++ +++V SPDA
Sbjct: 116 AKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDA 173
>UniRef50_O26877 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Methanobacteriaceae|Rep: Ribose-phosphate
pyrophosphokinase - Methanobacterium thermoautotrophicum
Length = 285
Score = 153 bits (370), Expect = 9e-36
Identities = 94/269 (34%), Positives = 145/269 (53%), Gaps = 5/269 (1%)
Query: 57 SSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLME 116
S+ LA + D L L V T+KF + E + + E V GE V +VQS ++NLME
Sbjct: 6 SASQKLAASVADLLDEPLCPVETRKFPDGERYIRVKEEVEGE-VTVVQSTGYPQDENLME 64
Query: 117 LLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDL 176
LL MI K A V A IP F Y RQ+++ KS ++AK+VA++L +GAD I+T++L
Sbjct: 65 LLFMIENLKDLGADYVRAAIPYFGYGRQERRFKSGEAVSAKIVAHLLEAAGADEIVTVNL 124
Query: 177 HASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEF 236
H + + FF +PV L A P I E+I ++++PD G ++D L E
Sbjct: 125 HENCLSEFFRVPVRELSAMPL----IAEHISFLDDPVIIAPDKGALGHAREVSDILGCEC 180
Query: 237 ALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILT 296
+ K R V + V DV+ + A++VDD+ T GTI +AA L + GA+ +
Sbjct: 181 DYMEKVRISPEVVETRVSDLDVEGKDAVVVDDIISTGGTIVNAAGILGKCGASSITVCCV 240
Query: 297 HGIFSGPAISRINNACLEAVVVTNTIPQE 325
H + A+ +I +A +E V+ T+T+ +
Sbjct: 241 HPVLVEDALLKIFSAGVERVIATDTLKSD 269
>UniRef50_Q4XQD5 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=1; Plasmodium chabaudi|Rep: Ribose-phosphate
pyrophosphokinase, putative - Plasmodium chabaudi
Length = 465
Score = 151 bits (367), Expect = 2e-35
Identities = 120/397 (30%), Positives = 200/397 (50%), Gaps = 48/397 (12%)
Query: 3 VHKSNQSDSV-ASPLATTSGLVSMKSTITLEDVVNKLDHVLPLTTRMPNIKVFSGSSHPD 61
++KS ++S A+ L +S +V + +D +K ++ L+ N+++FS +SH +
Sbjct: 57 INKSKNTNSKDANNLDKSSAVVPENNKNKSKD--DKYEYYQELS-EYSNMQIFSSNSHHE 113
Query: 62 LAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQS---GSGEINDNLMELL 118
LA +I LGI LG+ K+S+ E ++I + VRG DVYI+ S G +++ LMEL
Sbjct: 114 LANEICSNLGISLGRAYIGKYSDGEITLQIMDEVRGRDVYIIHSTPAGGKDVHSRLMELF 173
Query: 119 IMINACKIASASRVTAVIPCFPYARQDKKD---KSRAPITAKLVANILSVSGADHIITMD 175
+ ++ + +SA +V V+P Y+RQ+K+ + + A +A +L GAD II +D
Sbjct: 174 LFVSTLRRSSAKKVIVVLPYLNYSRQNKQTGYFNNMHSLGAPEIAILLQTCGADSIIAVD 233
Query: 176 LHASQIQGF------FDIPVDNLFAEPAVLKWIKE-----------NIPD-------WKT 211
L+ +I+GF F P+ N+ + ++++K+ NI W
Sbjct: 234 LNNPRIEGFSTDQKLFQPPLMNINPQSLAVEYLKKKKLHNPVIVPINIDGAEKAKEFWVR 293
Query: 212 SIVVSPDAGGAKRVTSIADRLNVEFALIHKERK--------KANEVASM-----VLVGDV 258
S D G V+S D + E K K N S+ +VGD+
Sbjct: 294 MKKHSNDVGFTTLVSSTYDGTSTRGEAPSNESKDSSKMLTNKQNNTNSLENEKITIVGDI 353
Query: 259 KDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVV 318
KD I+V+D+ DT A L AGA K+Y TH I S +S+IN++C++ VV
Sbjct: 354 KDCDCIIVNDILDTGEKSKKVAALLKNAGARKIYLYATHAILSDGCVSKINDSCIDEVVT 413
Query: 319 TNTIPQERHMQECPKIQCIDVSMMLAEAVRRTHNGES 355
TNTI R + C K+ + V+ ++AE ++R +N +S
Sbjct: 414 TNTIHIPRDVC-CEKMHILSVAKLVAEGIKRFNNEQS 449
>UniRef50_UPI00006CD8E2 Cluster: ribose-phosphate pyrophosphokinase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
ribose-phosphate pyrophosphokinase family protein -
Tetrahymena thermophila SB210
Length = 447
Score = 148 bits (359), Expect = 2e-34
Identities = 96/320 (30%), Positives = 173/320 (54%), Gaps = 12/320 (3%)
Query: 45 TTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQ 104
+++ + VF+GS + +LA+++V +L I L ++ K ET +EI +SVRG+ V+++Q
Sbjct: 93 SSQKSGLLVFTGSGNRELAKEVVSQLDIQLSRISIHKNPESETEIEILDSVRGKRVFVIQ 152
Query: 105 S-GSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQD--KKDKSRAPITAKLVAN 161
S INDN+MEL +M +A K + A++VT ++P F Y+RQ + DK R + +
Sbjct: 153 SLCQPSINDNIMELYLMCSALKRSGAAKVTCIVPYFAYSRQTSAESDKERRSLNGSDICL 212
Query: 162 ILSVSGADHIITMDLHASQIQGFF--DIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDA 219
+L G D +IT++ +++GFF +P+ N+ V+ ++ E + I +
Sbjct: 213 MLQTMGCDQVITINYGQIEVKGFFAPRVPILNIDVNEMVVPYLLEKGIENPVLIGAHLRS 272
Query: 220 GGAKRVTSIADRLNV---EFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTI 276
KR+ + N+ +L R A ++ + DVK+R IL +++ D+ ++
Sbjct: 273 RNVKRLIGLHKIFNLFDQNPSLGFMIRGNAEKIE--YIGEDVKNRDCILFENLIDSGNSL 330
Query: 277 CHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQC 336
+ KL + GA +++ HG+F+ A I N+ +E +VTNT E + PKIQ
Sbjct: 331 QELSLKLHKDGARRIFWFSPHGLFTDNAQKLIKNSFVEECIVTNTC--EEVKPQHPKIQY 388
Query: 337 IDVSMMLAEAVRRTHNGESV 356
+ V+ +LAE + H+G S+
Sbjct: 389 LSVAKLLAEVISFLHSGHSL 408
>UniRef50_Q8TUT6 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Methanopyrus kandleri|Rep: Ribose-phosphate
pyrophosphokinase - Methanopyrus kandleri
Length = 291
Score = 144 bits (350), Expect = 2e-33
Identities = 83/271 (30%), Positives = 146/271 (53%), Gaps = 3/271 (1%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
V + S L +++ + L +L V +F + E V + + G V +V S S ++
Sbjct: 3 VLATSEGVKLGRRLAEELDAELAPVEEDRFPDGEQIVRVPPELDGT-VVVVHSMSPPQDE 61
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
NL++ +I ++A + A V A++P Y+RQD++ + P++ + VA +S + AD +I
Sbjct: 62 NLVKAIITLDAARENGAEEVIAIVPYMAYSRQDRRFEPGEPVSFRAVARAVSAN-ADALI 120
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
T+DLH +FD+P +N+ A + K++ E + + +V+ PD G + +A
Sbjct: 121 TVDLHEPGTLKYFDVPAENVSAAEELGKYLAERF-EGEDLVVIGPDEGARELAREVASIC 179
Query: 233 NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVY 292
VE+ + K+R +EV DV+ RT +LVDDM DT GT+ AA L + GA +Y
Sbjct: 180 GVEYDHLEKKRLSGDEVEIHPKELDVEGRTVVLVDDMIDTGGTMVEAARALRDQGAGTLY 239
Query: 293 AILTHGIFSGPAISRINNACLEAVVVTNTIP 323
A TH + + A +R+ + E ++ T+T+P
Sbjct: 240 AACTHALLTRNAATRLLASGFEDIIATDTVP 270
>UniRef50_Q2GCV8 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep:
Ribose-phosphate pyrophosphokinase - Neorickettsia
sennetsu (strain Miyayama)
Length = 305
Score = 144 bits (349), Expect = 3e-33
Identities = 91/303 (30%), Positives = 159/303 (52%), Gaps = 10/303 (3%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGES--VRGEDVYIVQSGSG 108
+KV GS L Q+I L + + + +F + E+ V + + G V ++QS
Sbjct: 1 MKVLMGSKAGKLGQEIASLLNLAVVRAQANRFPDGESDVLVHHEDVIPGTKVLVIQSLCS 60
Query: 109 EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGA 168
+ + +ME L +++A + V P F YAR D+ + I+AK+VA ++
Sbjct: 61 DAD--IMEFLFIVDALNRLGVRDIALVSPYFGYARADRIVAPGSAISAKVVARLIG-ERI 117
Query: 169 DHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSI 228
+ +D+H Q +GFF+IPV N+ P L +KE++ +V+PD G K++ +
Sbjct: 118 SLLFVLDVHFPQFEGFFEIPVYNIL--PWTL--LKESVHVGHNMALVAPDVGAVKKLKPL 173
Query: 229 ADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA 288
++ L +++K R +A +VG++ R I+VDD+ GT+C++A KL E GA
Sbjct: 174 SEELGTNLVIMNKRRPRACLSEVTEVVGEIHGRDCIIVDDIVCGGGTLCNSAAKLKELGA 233
Query: 289 TKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVR 348
V A +THG+FSG A +I ++ ++ +VVTN+IP + KI+ I + +LA +
Sbjct: 234 KSVAAFVTHGVFSGSARQKIMDSQIDRIVVTNSIPGP-GCEAKGKIEIISAADLLARKIH 292
Query: 349 RTH 351
+
Sbjct: 293 SVY 295
>UniRef50_Q8KKS6 Cluster: Ribose-phosphate pyrophosphokinase
protein; n=1; Rhizobium etli CFN 42|Rep:
Ribose-phosphate pyrophosphokinase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 313
Score = 138 bits (335), Expect = 2e-31
Identities = 82/271 (30%), Positives = 141/271 (52%), Gaps = 5/271 (1%)
Query: 79 TKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAVIPC 138
T+ FSN + V + G +V +VQ+ ++D L EL + + A + +TAV+P
Sbjct: 45 TQVFSNGQMAVTPRDGGLGGNVVVVQTFPDSVHDRLFELFLALGAVRARGPRTITAVLPY 104
Query: 139 FPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAV 198
PY+R D+ P+ +++A I+ G D +IT +LH Q+ F PV NL PA+
Sbjct: 105 LPYSRSDRPAFDGGPVPVRILAGIIETLGIDRLITFELHVPQLCAAFACPVVNLQFAPAL 164
Query: 199 LKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEV-ASMVLVGD 257
++ + D +VVSPD GGAKR +A L FA++ K R+ ++ S+ ++GD
Sbjct: 165 VRHLGSAAVD--GDMVVSPDFGGAKRAEHLAALLGCPFAVMRKHRRDDDDFRESVEILGD 222
Query: 258 VKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVV 317
V RT IL+DD ++ T AA L AGA K+ H IF+ + ++ +V
Sbjct: 223 VAGRTIILIDDEINSGQTAFSAAAHLKAAGARKITLAAAHAIFTPSLNENWGRSQIDRIV 282
Query: 318 VTNTIPQERHMQECPKIQCIDVSMMLAEAVR 348
VT+++ + + + ++ + + +A A++
Sbjct: 283 VTDSVGRTDNFPD--SVEVVSIGNEIAGALQ 311
>UniRef50_Q58761 Cluster: Ribose-phosphate pyrophosphokinase; n=7;
Methanococcales|Rep: Ribose-phosphate pyrophosphokinase
- Methanococcus jannaschii
Length = 284
Score = 138 bits (335), Expect = 2e-31
Identities = 85/273 (31%), Positives = 142/273 (52%), Gaps = 5/273 (1%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
V SGS +LA K+ L L +V K+F + E V I + + ++ I+ + + ND
Sbjct: 3 VVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQ-ND 61
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
++E +++ +A + ++T V P YARQDKK I+ + +A I S + D +I
Sbjct: 62 AIVETILLCDALRDEGVKKITLVAPYLAYARQDKKFNPGEAISIRALAKIYS-NIVDKLI 120
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
T++ H + I+ FF IP A P + +++K+ + D IV++PD G + + + L
Sbjct: 121 TINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLND---PIVLAPDKGALEFAKTASKIL 177
Query: 233 NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVY 292
N E+ + K R E+ D KDR +VDD+ T GT+ A + L E GA K+
Sbjct: 178 NAEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKII 237
Query: 293 AILTHGIFSGPAISRINNACLEAVVVTNTIPQE 325
A H + G A++++ +A +E VV T+T E
Sbjct: 238 AACVHPVLIGDALNKLYSAGVEEVVGTDTYLSE 270
>UniRef50_UPI00015BACA3 Cluster: ribose-phosphate pyrophosphokinase;
n=1; Ignicoccus hospitalis KIN4/I|Rep: ribose-phosphate
pyrophosphokinase - Ignicoccus hospitalis KIN4/I
Length = 298
Score = 138 bits (334), Expect = 2e-31
Identities = 81/265 (30%), Positives = 137/265 (51%), Gaps = 4/265 (1%)
Query: 62 LAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMI 121
L +V L + + KKF + E+ V I V GEDV +V +G + ND ++E+L+ I
Sbjct: 13 LCDGLVASLNAEAHFIERKKFPDGESYVRIPIPVSGEDVLVVHTGFPDQNDRVIEVLLTI 72
Query: 122 NACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQI 181
+ K A VT ++P PYARQD++ + P++ K + LS D+++ +D+H
Sbjct: 73 DTLKDLGAESVTLLMPYMPYARQDRRFREGEPVSIKTLLKTLSNLDLDYLVVVDIHKEYS 132
Query: 182 QGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHK 241
F N+ P + + IK+ + D +V++PD G R S+A L + + K
Sbjct: 133 LSEFGGGAFNVSVLPYLAEKIKDEVED---PLVLAPDRGATARAKSVASVLKAPWDYLEK 189
Query: 242 ERKK-ANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIF 300
R + EV + +T I+VDDM T T+ AA++L AGA +V A++ H +
Sbjct: 190 RRDRVTGEVTIRPKEISAEGKTVIIVDDMVSTGSTLALAAKQLKAAGAKRVLALVAHALM 249
Query: 301 SGPAISRINNACLEAVVVTNTIPQE 325
G A +++ A +E V+ NT+ ++
Sbjct: 250 VGDAENKLREAGVERVITANTLARD 274
>UniRef50_A3DNX0 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Staphylothermus marinus F1|Rep: Ribose-phosphate
pyrophosphokinase - Staphylothermus marinus (strain ATCC
43588 / DSM 3639 / F1)
Length = 304
Score = 138 bits (334), Expect = 2e-31
Identities = 88/302 (29%), Positives = 153/302 (50%), Gaps = 9/302 (2%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIG--ESVRGEDVYIVQSGSGEI 110
V +G ++ A+K LG +L + TK F + E V I E + G V I+ +
Sbjct: 7 VIAGKNYETFAEKYASLLGYELVDIQTKIFPDGEYYVRIKKPELISGNKVVIINTMYPRQ 66
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
ND+L+E L++I+A + + A + +IP YARQDK P+TA +V ++ GA+
Sbjct: 67 NDSLLETLMLIDAARRSGAKDIVVIIPYLAYARQDKVFLEGEPVTASIVVKMIRTIGANA 126
Query: 171 IITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIAD 230
++ +D+H+ + F+ N+ +++ + D IV++PD G R A+
Sbjct: 127 LVVVDIHSVKTLEDFNGKTLNILVSDELVEKALSILND---PIVIAPDKGALHRARYAAE 183
Query: 231 RLNVEFALIHKERKK-ANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGAT 289
R +E+ + K+R + E++ M + R +++DD+ T GTI +A L GA
Sbjct: 184 RHGLEYDYLIKKRDRITGEISMMPKELRIDGRDIVIIDDIISTGGTIANATRILRSHGAR 243
Query: 290 KVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRR 349
K+ THG+F G A +I +A +E + V NT+ H + P I+ +DVS + +R
Sbjct: 244 KIVVAATHGLFIGNAFEKIRSAGVEKIYVANTL-GITHKE--PLIETVDVSEKVVTEMRN 300
Query: 350 TH 351
+
Sbjct: 301 NN 302
>UniRef50_O59586 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Thermococcaceae|Rep: Ribose-phosphate pyrophosphokinase
- Pyrococcus horikoshii
Length = 287
Score = 138 bits (334), Expect = 2e-31
Identities = 80/248 (32%), Positives = 137/248 (55%), Gaps = 7/248 (2%)
Query: 76 KVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAV 135
K KKF + E V I E GE+V +VQS +++L+E +I+ +A K A ++ V
Sbjct: 26 KTEIKKFPDGEKYVRILE--HGEEVIVVQSTYRPQDEHLIETIIIGDALKEAGFEKLKLV 83
Query: 136 IPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAE 195
+P Y+RQD+ K PI+ + + +L + D + D+H + FF N++
Sbjct: 84 VPYLAYSRQDRVTKEGEPISVRAIMKMLGLY-YDELYVFDIHNPKTLDFFPGKAVNIYPA 142
Query: 196 PAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLV 255
+ ++ ++ + + +V++PD G +R +A+ L +E++ KER EV +
Sbjct: 143 KVIAEYFRDKL---ENGLVLAPDRGALERAKEVANILGLEYSHFEKERISPTEVKMTPVD 199
Query: 256 GDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEA 315
+VK R ++VDD+ T GT+ AAE L + GA KV+ + THG+F+ AI R++ A ++
Sbjct: 200 VNVKGRNVLIVDDIISTGGTMIRAAEILKDLGAEKVFVVATHGVFAEGAIERVSKA-VDE 258
Query: 316 VVVTNTIP 323
+ VTNTIP
Sbjct: 259 LAVTNTIP 266
>UniRef50_O83317 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=2; Treponema|Rep: Phosphoribosyl pyrophosphate
synthetase - Treponema pallidum
Length = 421
Score = 130 bits (315), Expect = 4e-29
Identities = 98/314 (31%), Positives = 162/314 (51%), Gaps = 37/314 (11%)
Query: 82 FSNMETCVEIGESVRGEDVYIVQS---------GSGE------INDNLMELLIMINACKI 126
F N E +I E +RG+DV+I Q +G+ +ND++M L++ I+A +
Sbjct: 92 FLNGELKTQINECIRGKDVFIFQDVENHQPVLVNNGKSKKIFSVNDHVMMLIVTIDAVRH 151
Query: 127 ASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQ-GFF 185
A A RVT V+P +PY+RQ KK R +TA L+ ++ G HI+T+DLH+ +I+ F
Sbjct: 152 AGAGRVTLVLPTYPYSRQHKK-CGREGLTAGLLGSVYEYLGVSHIVTLDLHSREIENAFH 210
Query: 186 DIPVDNLFAEPAVLKWIK--ENIPDWKTS-IVVSPDAGGAKRVTSIADRLNVEFALIHKE 242
++NL A +++ + EN+ D +VV+PD+G +R + L A+I+K
Sbjct: 211 RTRLENLHASYQIIRELAKIENLSDPDIPFVVVAPDSGAVERNKFYSSGLKKPLAMIYKV 270
Query: 243 R--------KKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAI 294
R K + + + L+GDV+ +TA + DDM + GT+ A E L GA +V A
Sbjct: 271 RDYSVVAQNAKQSNIVEINLLGDVEGKTAFIADDMLGSGGTMLKAMEFLKSRGAKQVIAA 330
Query: 295 LTHGIFSGPAISRINNA----CLEAVVVTNTI--PQERHMQECPKIQCIDVSMMLAEAVR 348
++ F+G A+ + A ++ TN + Q H Q + DVS + A +
Sbjct: 331 VSLPFFTGNALELFDEAYEKRYFSRIIGTNAVFHTQLSHKQWYTE---TDVSGLFARVIA 387
Query: 349 RTHNGESVSYLFSN 362
R H+ +S+S L +
Sbjct: 388 RIHHNQSLSSLLDD 401
>UniRef50_Q660Y0 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=3; Borrelia burgdorferi group|Rep: Phosphoribosyl
pyrophosphate synthetase - Borrelia garinii
Length = 406
Score = 130 bits (313), Expect = 7e-29
Identities = 96/301 (31%), Positives = 153/301 (50%), Gaps = 31/301 (10%)
Query: 81 KFSNMETCVEIGESVRGEDVYIVQS---------GSGE-----INDNLMELLIMINACKI 126
KF+N E EI +++R +D++IVQ S E +ND++M L+ I+AC
Sbjct: 87 KFANGEFKTEILKTIRNKDIFIVQDVANTYEVEINSSEKIIMTVNDHIMNLMTTIDACMQ 146
Query: 127 ASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFF- 185
A A+ V+ +IP +PY+RQDKK SR +TA L+ L G HI+T+D+H+ I+ F
Sbjct: 147 AKANSVSVIIPSYPYSRQDKK-HSRECLTASLIGRFLEELGIRHILTLDIHSKAIENVFR 205
Query: 186 DIPVDNLFAEPAVLKWIKENIPDWKTS--IVVSPDAGGAKRVTSIADRLNVEFALIHKER 243
+ +NL + K + + I D + S ++VSPD G R A L AL++KER
Sbjct: 206 KVYFENLNVSYEIFKSLGDLI-DIRDSNLVIVSPDTGAVSRNKFFASSLKSPLALLYKER 264
Query: 244 ---KKANEVAS-----MVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAIL 295
+ +N+VA L+GDV+ + + DDM T GT+ A + L GA K+ +
Sbjct: 265 DYSRVSNDVADSNISVTKLLGDVEGKNVFMSDDMLATGGTLIKAMKLLKSMGAKKIICGI 324
Query: 296 THGIFSGPAISRINNACLEA----VVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRTH 351
+ F+G AI + A E ++ TN + + P +V+ + A A+ +
Sbjct: 325 SLPFFNGDAIKYFDKAYEEGYFYKIIGTNAVCHNDELINKPWYHETNVAHLFANAIFAIY 384
Query: 352 N 352
N
Sbjct: 385 N 385
>UniRef50_A7DQD3 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Ribose-phosphate pyrophosphokinase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 127 bits (307), Expect = 4e-28
Identities = 81/274 (29%), Positives = 138/274 (50%), Gaps = 4/274 (1%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+ V G S DL +K+ ++ +L K + F + E+ + + ++ +VQS +
Sbjct: 5 LSVICGKSSEDLGKKLARKIKANLVKSEVRIFPDGESKITLKGNISKRKSIVVQSIYPPV 64
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
+ NL++ L +I+ K S S V VIP YARQD++ +T K++A + +GA
Sbjct: 65 DTNLIQALSLISKAKETS-SEVIVVIPYMGYARQDREFLPGEIVTMKVLAKLFKGAGASK 123
Query: 171 IITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIAD 230
+I +D+H+ +F I N+ A P + + K+ K +VVSPD GG +R A
Sbjct: 124 LIAVDIHSLIGLKYFTIKSKNVSAVPDLAAYFKKL--SLKNPLVVSPDQGGKERAKEFAK 181
Query: 231 RLNVEFALIHKER-KKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGAT 289
+ +EF + K+R +K +V +V R ILVDDM T G+I +A + L +
Sbjct: 182 EMGIEFIALQKKRDRKTGKVQIKTKQANVIGRDLILVDDMISTGGSIVNATKFLKKEKCK 241
Query: 290 KVYAILTHGIFSGPAISRINNACLEAVVVTNTIP 323
+V+ TH + A +I + + ++ NTIP
Sbjct: 242 RVFVACTHALLMNDAEKKIKKSGVTKIISANTIP 275
>UniRef50_A4WYL1 Cluster: Putative uncharacterized protein; n=1;
Rhodobacter sphaeroides ATCC 17025|Rep: Putative
uncharacterized protein - Rhodobacter sphaeroides ATCC
17025
Length = 347
Score = 126 bits (303), Expect = 1e-27
Identities = 89/313 (28%), Positives = 151/313 (48%), Gaps = 18/313 (5%)
Query: 58 SHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVY---IVQSGS-GEINDN 113
SHP L + R G+ + + FS E + SVRG +V ++ +G G +ND
Sbjct: 34 SHP-LGHAVARRAGLSVAMHEARAFSGGEHKLRPLVSVRGHEVCLFSVLHAGEVGSVNDA 92
Query: 114 LMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIIT 173
L+ LL+ C+ A+RV V P PY R+D++ K+R P+ VA ++ G D +IT
Sbjct: 93 LVRLLLFAACCRTNGAARVLIVSPWLPYMRKDRQTKARDPVNTAGVARLIEAVGVDGLIT 152
Query: 174 MDLH-ASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
+++H + Q F +L I + +VSPD GG KR + D +
Sbjct: 153 LEVHNLAAFQNAFRCATVHLDTCRLFATEILSRSAG-RPLCLVSPDGGGVKRAALLRDAV 211
Query: 233 N------VEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEA 286
V F + K R + V+ + G+V+ RT +VDDM ++ GT+ AA E
Sbjct: 212 EQVSTRPVGFGFMEKHRSE-GVVSGDLFAGEVEGRTVWIVDDMIESGGTLLRAARACAER 270
Query: 287 GATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEA 346
GA +V+ + TH + A+ R+ + + ++ VT++ + P++ C+ V+ ++ A
Sbjct: 271 GAAEVHLVATH-LVDAAAVVRLADPSVGSLTVTDSAVS---AEPTPQLHCLSVAPLIGAA 326
Query: 347 VRRTHNGESVSYL 359
+ + H G V L
Sbjct: 327 LAQIHRGGPVGPL 339
>UniRef50_Q6Z2L5-2 Cluster: Isoform 2 of Q6Z2L5 ; n=1; Oryza sativa
(japonica cultivar-group)|Rep: Isoform 2 of Q6Z2L5 -
Oryza sativa subsp. japonica (Rice)
Length = 365
Score = 125 bits (301), Expect = 2e-27
Identities = 60/121 (49%), Positives = 89/121 (73%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+++FSG+++P L+Q+I LG++LGK+ K+F++ E V++ ESVRG DV++VQ
Sbjct: 80 LRIFSGTANPSLSQEIASYLGLELGKINIKRFADGEIYVQLQESVRGCDVFLVQPTCPPA 139
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
N+NLMELLIMI+AC+ ASA +TAVIP F YAR D+K + R I AKLVAN+++ D+
Sbjct: 140 NENLMELLIMIDACRRASAKNITAVIPYFGYARADRKSQGRESIAAKLVANMITPVILDY 199
Query: 171 I 171
+
Sbjct: 200 L 200
Score = 118 bits (283), Expect = 3e-25
Identities = 60/164 (36%), Positives = 94/164 (57%), Gaps = 2/164 (1%)
Query: 196 PAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLN-VEFALIHKERKKANEVASMVL 254
P +L ++ +VVSPD GG R + A +L+ A++ K R N M L
Sbjct: 194 PVILDYLASKTICSDDLVVVSPDVGGVARARAFAKKLSDAPLAIVDKRRHGHNVAEVMNL 253
Query: 255 VGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLE 314
+GDV+ + A+++DDM DT GTI AE L + GA +VYA TH +FS PAI R+++ +
Sbjct: 254 IGDVRGKVAVMMDDMIDTAGTIAKGAELLHQEGAREVYACCTHAVFSPPAIERLSSGLFQ 313
Query: 315 AVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRTHNGESVSY 358
V++TNTIP + + P++ + V+ +L E + R H+ SV +
Sbjct: 314 EVIITNTIPLKED-KSFPQLTILSVANLLGETIWRVHDDCSVGH 356
>UniRef50_A3H7E6 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Caldivirga maquilingensis IC-167|Rep: Ribose-phosphate
pyrophosphokinase - Caldivirga maquilingensis IC-167
Length = 286
Score = 124 bits (298), Expect = 5e-27
Identities = 76/264 (28%), Positives = 133/264 (50%), Gaps = 9/264 (3%)
Query: 61 DLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIM 120
DL + R+G + ++ K F + E + + +V+G DV V + L+ ++++
Sbjct: 13 DLGPNVASRIGAEAREITRKVFPDGEQYIRVEANVKGSDVLYVTRLYPNQDQGLIRVMLL 72
Query: 121 INACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQ 180
++A K A+RV IP PYARQD++ PI+ ++ N+L G D++ +D+H Q
Sbjct: 73 LDAVKGLGAARVGLFIPYMPYARQDRRFLEGEPISINVILNVLKGLGVDYLYVVDIHKPQ 132
Query: 181 -IQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALI 239
++G+ F K E + +V+SPD G R +A L VE+ +
Sbjct: 133 SLEGYPG------FINLKPFKLYAEGLGGLSKPVVISPDLGSLWRAEELAKALGVEYDYL 186
Query: 240 HKERKK-ANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHG 298
K R + + EV+ + +VK + +++DD+ T GTI AA L GAT + I TH
Sbjct: 187 EKHRDRYSGEVSFTLRNLNVKGKDVVIIDDIISTGGTIIGAAGMLRSMGATSINVIATHC 246
Query: 299 IFSGPAISRINNACLEAVVVTNTI 322
I G A +++ A ++ + +N+I
Sbjct: 247 IMIGDAEAKLTKA-VDKIHCSNSI 269
>UniRef50_Q12265 Cluster: Probable ribose-phosphate
pyrophosphokinase 5; n=6; Saccharomycetales|Rep:
Probable ribose-phosphate pyrophosphokinase 5 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 496
Score = 123 bits (297), Expect = 6e-27
Identities = 53/87 (60%), Positives = 70/87 (80%)
Query: 158 LVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSP 217
L+A++LS +GADH+ITMDLH Q GFFDIPVDNL+ +P +I+ IPD++ +++VSP
Sbjct: 225 LIAHLLSAAGADHVITMDLHDPQFPGFFDIPVDNLYCKPIAQNYIQHRIPDYQDAVIVSP 284
Query: 218 DAGGAKRVTSIADRLNVEFALIHKERK 244
DAGGAKR T+IAD L + FALIHKER+
Sbjct: 285 DAGGAKRATAIADALELSFALIHKERR 311
Score = 122 bits (294), Expect = 1e-26
Identities = 55/116 (47%), Positives = 85/116 (73%), Gaps = 2/116 (1%)
Query: 249 VASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRI 308
V + +LVGDV+++ I+VDD+ DT TI AA+ L + G+TKVYA++THG+FSG A+ RI
Sbjct: 379 VQTTMLVGDVRNKVCIIVDDLVDTSYTITRAAKLLKDQGSTKVYALITHGVFSGDALERI 438
Query: 309 NNACLEAVVVTNTIPQERHMQECPK--IQCIDVSMMLAEAVRRTHNGESVSYLFSN 362
+ ++ ++++NT+PQ+R +Q K + IDVS ++ EA+RR HNGES+S LF +
Sbjct: 439 GQSSIDKLIISNTVPQDRTLQYLGKDRVDVIDVSCIIGEAIRRIHNGESISMLFEH 494
Score = 114 bits (275), Expect = 3e-24
Identities = 57/97 (58%), Positives = 70/97 (72%)
Query: 48 MPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
M NI VF G SHP+L KI + L I KV KFSN ET + + ESVR +DVYI+QSG
Sbjct: 3 MSNIVVFGGDSHPELVTKICENLDIHPSKVELGKFSNGETNIALRESVREKDVYIIQSGC 62
Query: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQ 144
G++ND M+LLI+I+ACK ASASRVTAV+P Y+RQ
Sbjct: 63 GQVNDTFMQLLILISACKSASASRVTAVMPYLCYSRQ 99
>UniRef50_Q97Z86 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Sulfolobaceae|Rep: Ribose-phosphate pyrophosphokinase -
Sulfolobus solfataricus
Length = 291
Score = 120 bits (289), Expect = 6e-26
Identities = 74/272 (27%), Positives = 135/272 (49%), Gaps = 5/272 (1%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+ GS+ + + + L I L KV K F + E+ + + S+R E+V +VQ+ +
Sbjct: 3 IIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDK 62
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
+L+EL ++ + A ++TA++P Y+RQD++ K I+ K + +ILS G + ++
Sbjct: 63 HLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLV 122
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
++ H + +F + + + + IKE I D +++PD G R IA+ +
Sbjct: 123 VVEPHKPEELSYFKGELKIVHPYHQIARKIKEIIED---PFILAPDRGALDRARKIAEEI 179
Query: 233 NVEFALIHKER-KKANEVASMVLVG-DVKDRTAILVDDMADTCGTICHAAEKLIEAGATK 290
N ++ I KER + EV ++K + +++DD+ T GTI A GA
Sbjct: 180 NAPYSYIEKERDRTTGEVRIKEAPNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAKS 239
Query: 291 VYAILTHGIFSGPAISRINNACLEAVVVTNTI 322
V A H + G A R+ ++ ++ TNTI
Sbjct: 240 VTAAAIHLLLVGGAKERLREVGVKTLIGTNTI 271
>UniRef50_Q6L0L1 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Thermoplasmatales|Rep: Ribose-phosphate
pyrophosphokinase - Picrophilus torridus
Length = 288
Score = 118 bits (285), Expect = 2e-25
Identities = 73/249 (29%), Positives = 127/249 (51%), Gaps = 7/249 (2%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+ SS L + +L ++ V K+F + E V I ++ DV ++ G+ +
Sbjct: 4 IVPSSSSMKLTSSLASKLNAEIANVTRKRFPDGEMYVRIETDLKDRDVIVL--GNTSHDS 61
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
+L+E L+++NA + + AVIP F YARQ + P+++K+ + + AD I+
Sbjct: 62 DLIEYLLLLNAAYEEKPATLNAVIPYFGYARQHMRYNPGEPVSSKVFTKAIE-NFADSIM 120
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
+++H + F P N+ ++ + K + D+ V+SPD GG +R SIA L
Sbjct: 121 AVEIHDEETLKFSAKPFTNVKVYDSIADYHKNHDIDY----VISPDDGGYERAKSIAKYL 176
Query: 233 NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVY 292
V+ I K+R + V + D ++R ++VDDM T GT+ A+ L ++GA K+Y
Sbjct: 177 KVDAYYIEKKRIDSRTVEMKMPDIDSRNRNILIVDDMISTGGTVIKASRILKDSGAKKIY 236
Query: 293 AILTHGIFS 301
HG+FS
Sbjct: 237 VSAVHGVFS 245
>UniRef50_O28853 Cluster: Ribose-phosphate pyrophosphokinase 2; n=1;
Archaeoglobus fulgidus|Rep: Ribose-phosphate
pyrophosphokinase 2 - Archaeoglobus fulgidus
Length = 271
Score = 118 bits (284), Expect = 2e-25
Identities = 84/272 (30%), Positives = 138/272 (50%), Gaps = 18/272 (6%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+K+ S P LA+++ + GI++G V KKF + E V + E E V + G I
Sbjct: 1 MKIIPCPSSPLLARRVAEAAGIEIGGAVFKKFPDGELYVRVMEK---EGVVV-----GSI 52
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
N N +L+ +I A + ++ AV+P YARQDK + ++ K+VA +L S AD
Sbjct: 53 NSN-EDLIALIFALDVLENAK--AVVPYMGYARQDKVFQEGEAVSIKIVAEMLE-SRADE 108
Query: 171 IITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIAD 230
++T+++H+S F + NL A P V ++ K +++SPD G +RV + A
Sbjct: 109 VVTVNIHSSDAASHFS-KLKNLDAMPLVGEYFAG-----KDVVMISPDKGSMERVKTAAK 162
Query: 231 RLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATK 290
E+ + K R A V DV+ R ++VDD+ T GT+ AA L GA
Sbjct: 163 HAGCEWDYMEKRRIDATTVEITPKTIDVEGRDVVIVDDIISTGGTVAEAARILYGLGAKS 222
Query: 291 VYAILTHGIFSGPAISRINNACLEAVVVTNTI 322
V A H + + A ++ NA ++ ++ T+T+
Sbjct: 223 VSAACVHAVLAENAAIKLFNAGIKDIIATDTV 254
>UniRef50_Q222A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Rhodoferax ferrireducens T118|Rep: Ribose-phosphate
pyrophosphokinase - Rhodoferax ferrireducens (strain DSM
15236 / ATCC BAA-621 / T118)
Length = 328
Score = 117 bits (281), Expect = 6e-25
Identities = 88/311 (28%), Positives = 151/311 (48%), Gaps = 17/311 (5%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI-- 110
++S S AQ + LG+ L ++F + E + RG D ++V S G+
Sbjct: 12 LYSLDSDDTFAQGLAASLGVKLAPHEYRRFEDGEHKLRPLLDPRGSDTFVVHSLHGDAQN 71
Query: 111 --NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGA 168
+D L +LL+ I + A+RV AV+P YAR+D++ K P++ + VA + G
Sbjct: 72 SPHDKLCQLLMFIATLREHGAARVAAVVPYLAYARKDRQTKPFDPVSLRYVAQLFEAVGT 131
Query: 169 DHIITMDLH-ASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
++ ++ H + Q F P +L A A E D + + V SPD GG KR
Sbjct: 132 TQLMVLEAHNVAAFQNAFRCPTMHLEAHQAFNAMALELAGDARLA-VASPDPGGVKRAQL 190
Query: 228 IADRLN------VEFALIHKERKKANEVASMVLV-GDVKDRTAILVDDMADTCGTICHAA 280
+ L V FA++ K R+ A V+S LV G+V +L+DD+ + T+ AA
Sbjct: 191 WRESLETTLLRPVGFAMVDK-RRSAGVVSSENLVAGEVDGMRVLLLDDLIASGETMRRAA 249
Query: 281 EKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQECP---KIQCI 337
L ++GA +V A + HG+F+G A + + + +++T+++P R C K+
Sbjct: 250 LALRQSGAREVLACVAHGLFTGSAAQVLTDDSIARIIITDSVPPFRLPLACAARRKLSIA 309
Query: 338 DVSMMLAEAVR 348
+ A+A++
Sbjct: 310 SAVPLFAQAIK 320
>UniRef50_Q88JA5 Cluster: Ribose-phosphate pyrophosphokinase family
protein; n=3; Pseudomonas|Rep: Ribose-phosphate
pyrophosphokinase family protein - Pseudomonas putida
(strain KT2440)
Length = 319
Score = 116 bits (279), Expect = 1e-24
Identities = 90/305 (29%), Positives = 144/305 (47%), Gaps = 15/305 (4%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIN- 111
+F+ D + RLG L + + + E GESV G V + S G+ +
Sbjct: 8 LFALQGSQDYGNAVAQRLGRKLSAHEERDYEDGEHKCWPGESVDGRSVIVFHSLYGDAHH 67
Query: 112 ---DNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGA 168
D L LL A K A+A +VTAV P Y R+D+K + + I + VA ++ G
Sbjct: 68 SAHDKLCRLLFFCGALKDAAARQVTAVTPYLCYGRKDRKVEFQDAIITRHVARLMESCGV 127
Query: 169 DHIITMDLH-ASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
D I+ +D+H S + IP NL + + + + + VVSPD GG KR
Sbjct: 128 DRIVALDVHNPSAFDNAYRIPSWNLQCTQLFAQRLAPLLGE-QAVTVVSPDIGGVKRAEQ 186
Query: 228 IADRL------NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAE 281
L V A++ K R++A ++ LVG+V T I+ DD+ T T+ AA+
Sbjct: 187 FRQALAHLLARPVSVAMMEKHRQQAG-LSGEHLVGNVAGSTVIVFDDLISTGQTLLRAAQ 245
Query: 282 KLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQEC-PKIQCIDVS 340
+AGA+++ A THG+F+ ++ E V+V ++I R C ++ +D S
Sbjct: 246 ACRQAGASRMLAAATHGLFTTGG-ELFDSGAFERVLVADSIAPFRLPVRCLEQLDIVDTS 304
Query: 341 MMLAE 345
++AE
Sbjct: 305 ALVAE 309
>UniRef50_Q8IE40 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=4; Plasmodium|Rep: Ribose-phosphate
pyrophosphokinase, putative - Plasmodium falciparum
(isolate 3D7)
Length = 560
Score = 115 bits (276), Expect = 2e-24
Identities = 70/195 (35%), Positives = 112/195 (57%), Gaps = 13/195 (6%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQS---G 106
N+++FS +SH +LA +I LGI LG+ KFS+ E ++I + VRG D+YI+ S G
Sbjct: 175 NMQIFSSNSHHELANEICSNLGIGLGRAYVGKFSDGEIALQIMDEVRGRDIYIIHSTPAG 234
Query: 107 SGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDK--KDKSRA-PITAKLVANIL 163
+++ LMEL + I+ + +SA +VTAVIP Y+RQ K D + + A +A +L
Sbjct: 235 GKDVHSRLMELFLFISTLRRSSAKKVTAVIPYLNYSRQTKHLDDHNYVHSLGAPEIAILL 294
Query: 164 SVSGADHIITMDLHASQIQGF-----FDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPD 218
G D II++DLH ++I+GF F P+ N+ + +++ K+ + +VVS D
Sbjct: 295 QACGVDSIISVDLHNARIEGFSTGKKFQPPLMNINPQSLAVEYFKKK--KLRNPVVVSID 352
Query: 219 AGGAKRVTSIADRLN 233
GA+R R+N
Sbjct: 353 NEGAERTKEFWIRMN 367
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/122 (36%), Positives = 68/122 (55%), Gaps = 1/122 (0%)
Query: 238 LIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTH 297
++ K+ + +VGD+K ILVDD+ DT A L AGA K+Y TH
Sbjct: 428 IVDKKENDMYDKEKFTIVGDIKGCDCILVDDIIDTGEKSQKVAAILKNAGARKIYLYATH 487
Query: 298 GIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRTHNGESVS 357
I S I +INN+C++ VV TNTI ++ C K+ + V+ ++AE ++R HN +S++
Sbjct: 488 AILSDGCIEKINNSCIDEVVTTNTIHIPSNIC-CEKLHILSVAKLVAEGIKRAHNEQSLN 546
Query: 358 YL 359
L
Sbjct: 547 AL 548
>UniRef50_Q9HLV6 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Thermoplasma|Rep: Ribose-phosphate pyrophosphokinase -
Thermoplasma acidophilum
Length = 286
Score = 115 bits (276), Expect = 2e-24
Identities = 73/273 (26%), Positives = 143/273 (52%), Gaps = 10/273 (3%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+K+ S LA+K+ ++L +L ++F + E V + GEDV+I+ G+
Sbjct: 1 MKIIGLQSSSSLARKVAEQLHSELVLPEERRFPDGELYVRYDADLNGEDVFII--GNTHT 58
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
+ ++E+++ ++A + V + P + YARQ ++ + PI++++ I + S +
Sbjct: 59 DAEIIEMILSLSAVRDYQVKSVNIIAPYYGYARQHQRYRRGEPISSQIFTEIFA-SYSTS 117
Query: 171 IITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIAD 230
I T+D+H Q + + +L A+ +++ + + D+ VVSPD GG +RV +A+
Sbjct: 118 IATVDIHDEQTLSYSKVRFTDLHADRSIIDFYRHVDIDY----VVSPDDGGLQRVKHVAE 173
Query: 231 RLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATK 290
L ++ I K+R V D+ + +++DD+ T GTI ++ L + GA+K
Sbjct: 174 ALGKKYFYIEKKRIDDRTVEMKAPDIDLNGKKVLILDDIISTGGTIAKSSSILRQKGASK 233
Query: 291 VYAILTHGIFSGPAISRI-NNACLEAVVVTNTI 322
+Y HG+F + S+I NA + + VT+T+
Sbjct: 234 IYVSAIHGLFVNSSESKILENA--DEIHVTDTV 264
>UniRef50_Q8ZU24 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Pyrobaculum|Rep: Ribose-phosphate pyrophosphokinase -
Pyrobaculum aerophilum
Length = 284
Score = 113 bits (273), Expect = 5e-24
Identities = 79/268 (29%), Positives = 139/268 (51%), Gaps = 14/268 (5%)
Query: 61 DLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIM 120
DLA ++ + +G + ++ + F + E V + E+ RGE V +V +NDNL++L +
Sbjct: 10 DLAAEL-EGIG-PVAQIEERVFPDGEVLVRLPEA-RGE-VAVVARLYPAVNDNLIKLFLT 65
Query: 121 INACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQ 180
I+A A AS++ VIP PYARQD++ + PI++K V +L+ IIT+DLH
Sbjct: 66 IDALNDAGASKIILVIPYMPYARQDRRFRPGEPISSKTVLKLLAHLNVFGIITVDLHKGY 125
Query: 181 IQGFFD-IPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALI 239
+ + + + NL+ K + +V+SPD G R ++A L V +
Sbjct: 126 VAEYAPRLVIKNLYPAEEFAKAL------GGVDVVLSPDFGSVHRAEAVARLLQVPYTYF 179
Query: 240 HKERKKANEVASMVLVGDV--KDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTH 297
K R ++ +++ DV +++ +VDD+ T GT+ A + GA +VYA +TH
Sbjct: 180 EKYRDRSTGAITLIPRQDVDLRNKRVAIVDDILSTGGTLVDACKAAKTLGAAEVYAAITH 239
Query: 298 GIFSGPAISRINNACLEAVVVTNTIPQE 325
A R+ +C++ ++ T+T+ E
Sbjct: 240 CQLLKDARERV-RSCVDKIICTDTVLNE 266
>UniRef50_Q9YAW0 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Aeropyrum pernix|Rep: Ribose-phosphate pyrophosphokinase
- Aeropyrum pernix
Length = 309
Score = 112 bits (270), Expect = 1e-23
Identities = 77/273 (28%), Positives = 134/273 (49%), Gaps = 5/273 (1%)
Query: 56 GSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRG-EDVYIVQSGSGEINDNL 114
GS+ + ++ + +G+ L K V K F + E V I + G +VQS + +L
Sbjct: 14 GSASAEFSEGLSRNMGLKLVKPVFKLFPDEEEYVRIEGDISGFTGAIVVQSFERPASRSL 73
Query: 115 MELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITM 174
+ L++ +A K A R+ + P Y RQD+ P++ + V L+ SG + + ++
Sbjct: 74 VYSLLIADALKEAGVGRIVLMAPYMGYTRQDRVFLPGEPVSVRAVMRALASSGYNALASI 133
Query: 175 DLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNV 234
++H + +FD N+F +LK + I +I+V+PD G RV +A
Sbjct: 134 EVHKEYVLDYFDGSTLNIFPFTYMLK--ETGISCGDNTIIVAPDKGSLPRVERLARETGC 191
Query: 235 E-FALIHKERKK-ANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVY 292
+ + KER + EV D + + AI+VDD+ T GTI A++ L+E GA V+
Sbjct: 192 RSYGYLVKERDRITGEVRLAKSTVDPRGKNAIVVDDIISTGGTIALASQWLLENGANSVF 251
Query: 293 AILTHGIFSGPAISRINNACLEAVVVTNTIPQE 325
+ H + G A ++ A + VV NT+P++
Sbjct: 252 VLAAHYLGIGNAEEKMMKAGVSRVVTGNTLPRK 284
>UniRef50_Q5ZWR2 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Legionella pneumophila|Rep: Ribose-phosphate
pyrophosphokinase - Legionella pneumophila subsp.
pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM
7513)
Length = 303
Score = 111 bits (268), Expect = 2e-23
Identities = 73/274 (26%), Positives = 134/274 (48%), Gaps = 9/274 (3%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+FS ++A ++ + L +++G V +F + E ++I V + +V S + ++
Sbjct: 5 LFSLFDSSEIAGRLQESLQVEVGDVTFHRFPDTEWYLKINSEVNNRSLMVVDS-LNQPDE 63
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
++ LL K A +V + P Y RQDK+ IT++ A+ILS S D ++
Sbjct: 64 KILPLLFFAKTAKELGARKVGLIAPYLSYLRQDKRFHEGEGITSRYFADILSTS-FDWLM 122
Query: 173 TMDLHASQ---IQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIA 229
T+D H + + + IP L A + WIK ++P I++ PD + V IA
Sbjct: 123 TIDPHLHRYHSLDEIYSIPTFVLHATSMIATWIKHHVPK---PILIGPDMESEQWVADIA 179
Query: 230 DRLNVEFALIHKERKKANEVA-SMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA 288
++ + +A++ K R+ EV S+ + +++ T +LVDD+ T T+ + L +AG
Sbjct: 180 EKGSFSYAILEKIRRGDKEVTISVPTIPELESSTLVLVDDIISTARTMVETVKHLHQAGG 239
Query: 289 TKVYAILTHGIFSGPAISRINNACLEAVVVTNTI 322
+ I H +F+ A S ++ V+ NTI
Sbjct: 240 KSIVCIGVHALFAEDAYSLLSEMKGVQVITCNTI 273
>UniRef50_A1RWZ6 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Thermofilum pendens Hrk 5|Rep: Ribose-phosphate
pyrophosphokinase - Thermofilum pendens (strain Hrk 5)
Length = 276
Score = 110 bits (265), Expect = 5e-23
Identities = 72/256 (28%), Positives = 125/256 (48%), Gaps = 6/256 (2%)
Query: 70 LGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASA 129
+G +L V K F + E V + G + +V S L+ELL+ + A +
Sbjct: 1 MGDELVFVEKKVFPDGEIYVRVPSKPSGVAI-VVSSTHPPQERRLLELLLTVEALSSYAQ 59
Query: 130 SRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQI-QGFFDIP 188
V AV+P YARQDK+ PI+ K+V L +GA ++ +D+H ++ + IP
Sbjct: 60 GSVIAVVPYLAYARQDKRFLEGEPISIKVVLKALEAAGASGLLAVDVHQPRVLSEWLSIP 119
Query: 189 VDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKK-AN 247
N+ + ++ + K ++V++PD G +R +A+ + +F + KER +
Sbjct: 120 SKNVLPFEDIAGYLYGKV---KNAVVLAPDMGALERARRVAELIGADFDYLVKERDRVTG 176
Query: 248 EVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISR 307
EV +V R ++VDD+ T TI AA+ + GA+ V A+ TH + A+
Sbjct: 177 EVRVQPKSLEVNGRDVVIVDDIISTGKTIALAAKSALAQGASSVTAVCTHAVMVQGALDL 236
Query: 308 INNACLEAVVVTNTIP 323
+ + + VV T+T+P
Sbjct: 237 LYYSGVREVVATDTVP 252
>UniRef50_Q8PUX3 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Euryarchaeota|Rep: Ribose-phosphate pyrophosphokinase -
Methanosarcina mazei (Methanosarcina frisia)
Length = 295
Score = 109 bits (262), Expect = 1e-22
Identities = 77/285 (27%), Positives = 136/285 (47%), Gaps = 10/285 (3%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+K+ G + LA + LG + +F + E + I E + E V ++QS +
Sbjct: 13 LKIIGGPASQLLASRTARALGTEPVLCEFNRFPDGELYLRIAEEIENEKVTLIQSTPTD- 71
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
+ + LL +I+AC+ A+ + VIP YARQDKK KS P++A+ +A ++ AD
Sbjct: 72 -SDFVALLQLIDACE--GAAEINVVIPYMGYARQDKKFKSGEPVSARAIARCIN---ADR 125
Query: 171 IITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIAD 230
+ T+++H + F P +NL A + ++ + ++V+PD G V ++A
Sbjct: 126 VFTINIHEKSVLEHFPCPAENLDAAALIGSYVAGF--GLERPMLVAPDEGARGLVKNVAS 183
Query: 231 RLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATK 290
+ + K R + V DV R +LVDDM T GT+ + L GA
Sbjct: 184 GHGFDHDHLQKTRLSGDTVVIKTKNLDVTGRHVVLVDDMIATGGTMAESIRMLKSQGAID 243
Query: 291 VYAILTHGIFSGPAISRINNACLEAVVVTNTIPQ-ERHMQECPKI 334
V+ H + + A R+ +A ++ ++ T+T+ + E + P I
Sbjct: 244 VHLACVHPVLTRNAALRLFHAGVKDIIGTDTLEKAESKLSVAPLI 288
>UniRef50_A1ZM86 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Microscilla marina ATCC 23134|Rep: Ribose-phosphate
pyrophosphokinase - Microscilla marina ATCC 23134
Length = 306
Score = 108 bits (259), Expect = 3e-22
Identities = 82/283 (28%), Positives = 140/283 (49%), Gaps = 12/283 (4%)
Query: 75 GKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTA 134
G + F + E I V G+DV IV G + + +EL M A + +T
Sbjct: 27 GATEVRFFPDGERYQRILSDVNGKDVVIV--GGTIADSDTLELFDMACAIEKYGGKTLTL 84
Query: 135 VIPCFPYARQDKKDKSRAPITAKLVANILS---VSG-ADHIITMDLHASQIQGFFD--IP 188
VIP F Y+ ++ K +T K A +LS ++G + ++ DLH S +Q +F+ I
Sbjct: 85 VIPYFGYSTMERAVKPGEVVTGKSRARLLSAIPITGRGNQVLLFDLHTSGLQHYFEGNIR 144
Query: 189 VDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANE 248
+++ + V++ +E + I+ D G AK V S+A+ + + A + K R A
Sbjct: 145 PVHIYCKDLVIEAAREL--GGEDFILACTDTGRAKWVESLANDMGIFAAFVFKRRISAEN 202
Query: 249 VASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRI 308
+ DVK + ++ DDM T G++ +AA+ +AGATK+ AI THGIF A+ R+
Sbjct: 203 TQITGINADVKGKNVVIYDDMIRTGGSLINAAQAYKDAGATKISAITTHGIFPNNAMERL 262
Query: 309 NNACL-EAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRT 350
+ L E VV T++ P + E P ++ + ++ + + T
Sbjct: 263 QKSGLFECVVSTDSHPNAVKV-ESPLLKIKSIDRLIIDKLEGT 304
>UniRef50_A2BKK7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Ribose-phosphate
pyrophosphokinase - Hyperthermus butylicus (strain DSM
5456 / JCM 9403)
Length = 222
Score = 108 bits (259), Expect = 3e-22
Identities = 57/184 (30%), Positives = 98/184 (53%), Gaps = 1/184 (0%)
Query: 140 PYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVL 199
PYARQD++ P++ + + L+ SGA+ +T+D+H + +F P N+ PA
Sbjct: 6 PYARQDRRFLRGEPVSVRALFYSLAASGAEAFVTVDIHKTVSLQWFPGPAVNVDPAPAFA 65
Query: 200 KWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKK-ANEVASMVLVGDV 258
+ ++ + + V++PD G R S+A+RL F + K R + E+ + DV
Sbjct: 66 EKLRPLLEGREKVYVIAPDQGAVGRAKSLAERLGAPFDYLEKVRDRVTGEIVLRPKLVDV 125
Query: 259 KDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVV 318
+L+DD+ T GT+ AA L E GA V A THG+F+G A+ ++ A + ++V
Sbjct: 126 SGAAVVLIDDIVSTGGTMAKAARMLYEQGAEVVIAAATHGLFAGEALEKMRKAGIVHILV 185
Query: 319 TNTI 322
+T+
Sbjct: 186 ADTV 189
>UniRef50_A0RYR1 Cluster: Phosphoribosylpyrophosphate synthetase;
n=1; Cenarchaeum symbiosum|Rep:
Phosphoribosylpyrophosphate synthetase - Cenarchaeum
symbiosum
Length = 283
Score = 107 bits (258), Expect = 3e-22
Identities = 80/274 (29%), Positives = 130/274 (47%), Gaps = 13/274 (4%)
Query: 82 FSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPY 141
F++ E+ + + R +VQS + NL++ L++++ A +V AV+P Y
Sbjct: 4 FADGESRLTLDAPRRRGTAVVVQSTQPPADTNLLQALLLVHKAGCI-ADKVVAVVPYMGY 62
Query: 142 ARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKW 201
ARQD++ +T ++VA + +GA + +D+H+ G F N+ A PA+ +
Sbjct: 63 ARQDREFLRGEIVTIEVVAGLFRAAGARRVYIVDMHSMAGLGLFGGLAVNVPAAPALAEH 122
Query: 202 IKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVG--DVK 259
K +VVSPDAGG R A L A + K R + ++ G D +
Sbjct: 123 FGRM--RLKDPLVVSPDAGGTARAAEFAGLLGTGHAALEKRRNRRTGSIAVSGPGLPDTE 180
Query: 260 DRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVT 319
+R +LVDDM + G+I AA L G ++Y TH + A RI A +E +V T
Sbjct: 181 NRDVVLVDDMISSGGSIIKAAGFLKGRGCGRIYVACTHALLVNDAERRIAEAGVEKIVGT 240
Query: 320 NTIPQERHMQECPKIQCIDVSMMLAEAVRRTHNG 353
NT+ +DVS ++AEA+ +G
Sbjct: 241 NTV--------WGGTSRVDVSGLVAEAIEDAASG 266
>UniRef50_A4CGY8 Cluster: Phosphoribosylpyrophosphate synthetase;
n=1; Robiginitalea biformata HTCC2501|Rep:
Phosphoribosylpyrophosphate synthetase - Robiginitalea
biformata HTCC2501
Length = 297
Score = 107 bits (257), Expect = 4e-22
Identities = 76/277 (27%), Positives = 132/277 (47%), Gaps = 9/277 (3%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+FS + +L + + ++ ++G+ +KF + E+ I V+G+ V +V + E +
Sbjct: 5 LFSLPGNQELTELLAKKMNAEIGECAIRKFPDGESYTRILSDVKGKCVVLVCT-LHEPDV 63
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
L+ L + + K A V P Y RQDK +++ ++S AD I
Sbjct: 64 KLLPLYFLSHTAKSLGAMCTCLVAPYLAYMRQDKVFNDGEGVSSTYFGKLIS-GFADSIT 122
Query: 173 TMDLHASQIQGF---FDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIA 229
T+D H +I +DIP + A A+ K+I ENI + +++ PD+ + V+ +A
Sbjct: 123 TVDPHLHRISSLGEVYDIPNRVIHAADAISKYINENIHN---PVLIGPDSESEQWVSDVA 179
Query: 230 DRLNVEFALIHKERKKANEV-ASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA 288
+ V F ++ K R +V S+ V K T +LVDD+ T T+ E L AG
Sbjct: 180 KKAEVPFTVLQKVRHGDRDVEVSVPNVAKYKVSTPVLVDDIISTAQTMIETTEHLKNAGM 239
Query: 289 TKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQE 325
I H +FSG A + +A ++ ++ NTIP +
Sbjct: 240 KPAICIGIHAVFSGNAYQDLWDAHVKDIITCNTIPHQ 276
>UniRef50_Q0W4S8 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
uncultured methanogenic archaeon RC-I|Rep:
Ribose-phosphate pyrophosphokinase - Uncultured
methanogenic archaeon RC-I
Length = 298
Score = 107 bits (257), Expect = 4e-22
Identities = 76/288 (26%), Positives = 133/288 (46%), Gaps = 9/288 (3%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+ +GSS P LA+ I R+G +KF + E V G+ + V VQ+ ND
Sbjct: 5 IIAGSSVPGLAKSIARRMGTKAHFPSIEKFPDGEIHVVEGDYTPAQTVVYVQTMHPHPND 64
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
L+E+++ ++ K A RV AVIP Y RQD + + + + +L +G + I+
Sbjct: 65 MLVEMMLTVDLLKELGAERVIAVIPYVGYMRQDARHVKGEAVAIRTMLKMLDFAGVNDIV 124
Query: 173 TMDLH-----ASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTS 227
+D+H ++ F I + + A + + + T +VV PD+ + +
Sbjct: 125 GVDMHLHRLGIEELASFSRIKIHEVSAVELLAARAGKGL---TTPLVVGPDSESERWAAA 181
Query: 228 IADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAG 287
A L ++ ++ K R A E+ VK R +++DD+ T GTI + L G
Sbjct: 182 AARVLGTDYDVLEKHRLSAREIEHRPRSMAVKGRDVLIIDDIVSTGGTIKDVIKSLKAQG 241
Query: 288 ATKVYAILTHGIFSG-PAISRINNACLEAVVVTNTIPQERHMQECPKI 334
A +V TH + S +++ + +E +V TNTI E + + +I
Sbjct: 242 AGQVNVACTHAVLSDIDSLTGLYRTGMEEIVSTNTINNESGIVDVSEI 289
>UniRef50_A3CS59 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Methanomicrobia|Rep: Ribose-phosphate pyrophosphokinase
- Methanoculleus marisnigri (strain ATCC 35101 / DSM
1498 / JR1)
Length = 285
Score = 107 bits (257), Expect = 4e-22
Identities = 76/271 (28%), Positives = 134/271 (49%), Gaps = 10/271 (3%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+++ S LA ++ ++LG L + +F + E ++ E +D ++ S +
Sbjct: 1 MRIISTERSQVLAARVAEKLGAPLVETKFTRFPDGELYLKCREL---DDETLIVSSIVD- 56
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
ND M+ L+ I+A A S+ T V+P Y+RQDK+ PI+A+ VA LS +G +
Sbjct: 57 NDMFMQTLLAIDA---ADQSKNTLVVPYLGYSRQDKRFSPGEPISARAVARALS-AGIER 112
Query: 171 IITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIAD 230
+ +++H + G F +P N+ PAV ++ + K +V++PD G + +A
Sbjct: 113 VYVVNIHDPGVLGHFGVPAKNVTIAPAVGGYVGDL--RLKNPLVLAPDEGAIGFASDVAA 170
Query: 231 RLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATK 290
+ + K R EV D R ++VDD+ T GT+ AA L E GA
Sbjct: 171 VGGWDCDHLEKTRLSGEEVRIAPKTIDAAGRDVVIVDDIISTGGTLATAACMLREQGAAS 230
Query: 291 VYAILTHGIFSGPAISRINNACLEAVVVTNT 321
++A HG+ + A +R+ A + +VV ++T
Sbjct: 231 IHAACVHGVLTSGAYTRLRAAGVSSVVSSDT 261
>UniRef50_A1RX65 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Thermofilum pendens Hrk 5|Rep: Ribose-phosphate
pyrophosphokinase - Thermofilum pendens (strain Hrk 5)
Length = 275
Score = 106 bits (255), Expect = 8e-22
Identities = 68/257 (26%), Positives = 129/257 (50%), Gaps = 10/257 (3%)
Query: 70 LGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASA 129
LG+ + F + E V + + ++ E+V V N+ L E ++ + + A
Sbjct: 2 LGLKYEVARVRSFPDGELYVRLPQGLKDEEVAYVVCYGRRPNEALAETVLAVEGLREKGA 61
Query: 130 SRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQG---FFD 186
+V V P PY RQD + ++++++A +L+ D +IT+D H +I+ F
Sbjct: 62 EKVVLVAPYLPYLRQDAEFTPGEVVSSRVIARLLAKLDVDALITVDPHLHRIRSLSELFP 121
Query: 187 IPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKA 246
P + A P + + ++ + T +VV+PD + + AD + + + K+R
Sbjct: 122 FPAIEVSAMPLLAAFFQK---EHGTGVVVAPDEEAERWAKTFADTIGAPYFVFEKQR-MG 177
Query: 247 NEVASMVLVGDVK-DRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAI 305
+E+ S + G VK TA++VDD+ T GT+ A+KL+EAG +YA +TH + A
Sbjct: 178 DEIVS--VTGAVKRGETAVIVDDIVSTGGTLGEVAQKLLEAGFRDIYACVTHALLVQDAE 235
Query: 306 SRINNACLEAVVVTNTI 322
+RI + ++ + T+++
Sbjct: 236 ARIFGSGVKEFISTDSV 252
>UniRef50_Q11BI1 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
Mesorhizobium sp. (strain BNC1)
Length = 326
Score = 105 bits (252), Expect = 2e-21
Identities = 73/268 (27%), Positives = 134/268 (50%), Gaps = 12/268 (4%)
Query: 63 AQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMIN 122
A+++ D G +LG + T++F + ET V I V+ + V +V S +D + L+ + +
Sbjct: 14 ARRLADDGGWELGALATRRFPDGETYVRILSDVKDKAVDLV-STLARPDDGFLRLIFVAD 72
Query: 123 ACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQ-- 180
A + A V + P Y RQD++ + IT++ A ++S S D ++T+D H +
Sbjct: 73 AARSLGAREVNLIAPYLSYMRQDRRFQPGEAITSRSFARLVS-SSFDRLVTVDPHLHRYP 131
Query: 181 -IQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALI 239
+ + IP L A P + WI + + ++V PD + V++IA R+ A++
Sbjct: 132 ALSALYTIPTITLHAAPLLADWIASAV---EKPLIVGPDEESEQWVSAIAARIGAPHAVL 188
Query: 240 HKER--KKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTH 297
K R + E+A L G + R +L DD+A + T+ AA +L G + + H
Sbjct: 189 RKVRHGDRNVEIALPDLTG-WRGRQPVLADDIASSGHTLIEAARQLPLQGFARPVVAVVH 247
Query: 298 GIFSGPAISRINNACLEAVVVTNTIPQE 325
IF+ + R+ C + +V ++++P E
Sbjct: 248 AIFAEDSFQRLAPLC-DRIVSSDSVPHE 274
>UniRef50_Q075L4 Cluster: Plastid ribose-phosphate diphosphokinase;
n=1; Prototheca wickerhamii|Rep: Plastid
ribose-phosphate diphosphokinase - Prototheca
wickerhamii
Length = 213
Score = 104 bits (249), Expect = 4e-21
Identities = 47/105 (44%), Positives = 77/105 (73%)
Query: 42 LPLTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVY 101
LP + +++FSG+++P L+Q++V LG++LG + K+F++ E V++GES+RG DV+
Sbjct: 109 LPQAGQPSRLRIFSGTANPGLSQEVVCYLGLELGAISIKRFADGEIYVQVGESIRGCDVF 168
Query: 102 IVQSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDK 146
++Q + +ND L+ELLI I+AC+ ASA +TAV+P F YAR D+
Sbjct: 169 LIQPTAPPVNDALVELLITIDACRRASARSITAVLPYFGYARADE 213
>UniRef50_A7MKK1 Cluster: Putative uncharacterized protein; n=1;
Enterobacter sakazakii ATCC BAA-894|Rep: Putative
uncharacterized protein - Enterobacter sakazakii ATCC
BAA-894
Length = 285
Score = 99 bits (238), Expect = 9e-20
Identities = 74/257 (28%), Positives = 128/257 (49%), Gaps = 15/257 (5%)
Query: 92 GESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAV-IPCFPYARQDKKDKS 150
GE R + +++ + + D+ M L + +A + R + + +P PYARQD+ +
Sbjct: 31 GELPRVASLMRIRAAAMKTMDDFMLLAQLTDAVRQHCDVRFSHLELPWLPYARQDRHMQP 90
Query: 151 RAPITAKLVANILSVSGADHIITMDLH----ASQIQGFFDIPVDNLFAEPAVLKWIKENI 206
K+ A L+ G D +I +D H A+ I+ IP + + L E
Sbjct: 91 GDSFALKVFARQLNTLGFDKVIVLDPHSEAAAAAIENLVAIPQERCLLQSKTL----ERA 146
Query: 207 PDWKTSIVVSPDAGGAKRVTSIADRLNV-EFALIHKERKKAN-EVASMVLV-GDVKDRTA 263
++V+PDAG K++ ++A V EFA++ K+R A E+ LV GDVK +
Sbjct: 147 LKAGELMLVAPDAGALKKIHAVAQAAGVHEFAILTKQRNVATGELTGFRLVDGDVKGKAV 206
Query: 264 ILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIP 323
++VDD+ D GT +A+ L +AGA+ V +THG+FS + +NN + T+ P
Sbjct: 207 LIVDDLCDAGGTFIGSAQVLRDAGASSVSLYVTHGVFSKGVENLLNNGIDKLYTTTSFAP 266
Query: 324 QERHMQECPKIQCIDVS 340
E + +++ ID++
Sbjct: 267 AELAQE---RVEMIDIN 280
>UniRef50_Q9HN88 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Halobacteriaceae|Rep: Ribose-phosphate pyrophosphokinase
- Halobacterium salinarium (Halobacterium halobium)
Length = 281
Score = 98.7 bits (235), Expect = 2e-19
Identities = 76/271 (28%), Positives = 123/271 (45%), Gaps = 9/271 (3%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+ SGSS LA + G LG V F + E V + +V GE IV S +D
Sbjct: 2 LLSGSSSQSLAAALAAATGERLGDVTYDSFPDGEQLVTVPPAVDGERAVIV--ASTPTSD 59
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
+E+L + +A + A AS + V+P YARQD P++A+ VA +S +G D ++
Sbjct: 60 AHIEVLQLQDAARDAGASEIITVLPYMGYARQDDAFDPGQPVSARAVARAIS-TGTDRVL 118
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
T++ H + FD+P + A P + + ++ D + +SPD G TS+ D
Sbjct: 119 TVNPHEDGVLECFDVPAAGVDAAPQLAAPLPADLTD---PVFLSPDHGATDLATSVRDAY 175
Query: 233 NVEFA-LIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKV 291
K R ++V R ++ DD+ T T+ A L + +V
Sbjct: 176 GTGVTDHFQKVRHSGSDVTVEPSEIQTAGRDVVVTDDIVATGTTMSEAITALDD--PARV 233
Query: 292 YAILTHGIFSGPAISRINNACLEAVVVTNTI 322
+ H + +G A ++ A +EAV T+TI
Sbjct: 234 FVATVHPLLAGSARLKLARAGVEAVYGTDTI 264
>UniRef50_O29666 Cluster: Ribose-phosphate pyrophosphokinase 1; n=2;
Archaeoglobus fulgidus|Rep: Ribose-phosphate
pyrophosphokinase 1 - Archaeoglobus fulgidus
Length = 284
Score = 96.7 bits (230), Expect = 8e-19
Identities = 75/270 (27%), Positives = 119/270 (44%), Gaps = 6/270 (2%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEIND 112
+ G ++ +A K+ G+ L ++ + E ++ GEDV I S ++
Sbjct: 3 ILVGGTNGLMALKVAKISGLPLCYSHVDRYPDGEKYFRFASNIDGEDVVIFNSMHPNPDE 62
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
+ E L++ A VT V P F YAR K A + K V +L +G II
Sbjct: 63 IIFETLLIAETAYSNGARSVTCVFPYFAYARSLDTVKGEA-LPIKTVVKVLKAAGVKKII 121
Query: 173 TMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL 232
T+D H + F + +L + ++ E D T V++PD A A +
Sbjct: 122 TVDFHLQE--NVFGVEHVDLTGMEKLAEYCLEEFSDSFT--VLAPDEKAAFWAEKFAAKA 177
Query: 233 NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVY 292
N + + K R A V L V+ ++VDD+ T GT+C AA AGA +V+
Sbjct: 178 NCDVVALRKIRIDAENVIIDDLRTGVEG-DVVIVDDIVSTGGTVCQAARIAKRAGARRVF 236
Query: 293 AILTHGIFSGPAISRINNACLEAVVVTNTI 322
TH I + A+ RI + +E +V T+TI
Sbjct: 237 VACTHAILARDAMMRILESGIEDIVSTDTI 266
>UniRef50_Q607P3 Cluster: Ribose-phosphate pyrophosphokinase family
protein; n=2; Proteobacteria|Rep: Ribose-phosphate
pyrophosphokinase family protein - Methylococcus
capsulatus
Length = 289
Score = 93.5 bits (222), Expect = 8e-18
Identities = 69/261 (26%), Positives = 121/261 (46%), Gaps = 4/261 (1%)
Query: 63 AQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMIN 122
+Q++ LG + +F + E+ V + VRG V V ND L+EL++
Sbjct: 10 SQELAGALGCPWRAIEVHRFPDGESRVRVPPDVRGTGV--VHRSLDRPNDKLVELVLAAE 67
Query: 123 ACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQ 182
+ R+ V P Y RQD ++ ++ K+V N+L+ D +IT+D H +I
Sbjct: 68 TLRGQGCDRLVLVAPYLCYMRQDIAFQAGEAVSQKVVGNLLA-RYFDALITVDPHLHRID 126
Query: 183 GFFD-IPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHK 241
+P+ + + + + D K +++ PD + V +IA + + A+ K
Sbjct: 127 RLEQAVPLKRVLSVSSATLVSRYLATDRKEWLLLGPDQESRQWVEAIAAQAGLPCAVASK 186
Query: 242 ERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFS 301
R EV + + +LVDD+A T T+ A L AG ++ I+TH +F+
Sbjct: 187 RRLGDREVGISLPQEAGAFKGVVLVDDIASTGTTLAETARLLARAGVARIDVIVTHALFT 246
Query: 302 GPAISRINNACLEAVVVTNTI 322
G A SR+ A + A+ T++I
Sbjct: 247 GDAWSRLKQAGVGAIASTDSI 267
>UniRef50_Q12E98 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Comamonadaceae|Rep: Ribose-phosphate pyrophosphokinase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 301
Score = 91.9 bits (218), Expect = 2e-17
Identities = 70/265 (26%), Positives = 124/265 (46%), Gaps = 9/265 (3%)
Query: 62 LAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMI 121
LA ++ L ++ +F + ET V I V G V + S + + + LL
Sbjct: 12 LAGRLARLLRCGWSELRLHRFPDGETLVRIDAPVMGRCVVLAGS-LNQPDGKTLPLLFAA 70
Query: 122 NACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQI 181
+A + ASRV V P Y RQD + + +T++ A +LS S D ++T+D H +
Sbjct: 71 DAARELGASRVGLVAPYLAYMRQDHRFNAGEAVTSRSYARLLSAS-LDFLVTVDPHLHRW 129
Query: 182 QGFFDI-PVDN--LFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFAL 238
+ DI P+ + A P + +W++ ++ +V+ PD + V +A + + +
Sbjct: 130 RNLGDIYPIRTQAVAAAPMIARWLRSHVDH---PLVIGPDQESGQWVAEVARLTDAPWTV 186
Query: 239 IHKERKKANEV-ASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTH 297
+ K R +V ++ G +T +L+DD+ T T+ AA L +AG I H
Sbjct: 187 LGKTRLGDRDVQVTLADGGPWPGKTPVLLDDIISTGQTLVAAATALTQAGMAAPLCIGVH 246
Query: 298 GIFSGPAISRINNACLEAVVVTNTI 322
+F A+ R+ +A + VV +TI
Sbjct: 247 ALFDSGALQRLQDAGVTRVVTCDTI 271
>UniRef50_A3W7X1 Cluster: Phosphoribosylpyrophosphate synthetase;
n=2; Roseovarius|Rep: Phosphoribosylpyrophosphate
synthetase - Roseovarius sp. 217
Length = 315
Score = 89.0 bits (211), Expect = 2e-16
Identities = 67/267 (25%), Positives = 123/267 (46%), Gaps = 11/267 (4%)
Query: 62 LAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNL-MELLIM 120
LA+ + LG DL + F + E+ + + + G DV + + D L + L
Sbjct: 12 LAEDLAPALGADLLTLDWHHFPDGESLISLPGDLDGADVAFLATLRDP--DRLALPLRFA 69
Query: 121 INACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQ 180
+ A RV + P Y RQD++ + ++A L A L S D ++++D H +
Sbjct: 70 AATAREMGARRVGLIAPYLGYMRQDRRFERGQAVSAPLFAQFLGES-FDWLVSVDPHLHR 128
Query: 181 I---QGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFA 237
I Q F +P + P + WI N+PD ++++ PD+ + V +A +
Sbjct: 129 IARLQDVFPMPAIRAVSAPLLATWISTNLPD---AVLLGPDSESQQWVAEVARLAGRPYE 185
Query: 238 LIHKERKKANEV-ASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILT 296
++ K R V S+ +++ T +++DD+A + T+ A E+L+ AG +
Sbjct: 186 VLRKVRSGDRSVDVSVPESAALREGTPVILDDIASSGVTMARAVERLLAAGTAAPVCLAI 245
Query: 297 HGIFSGPAISRINNACLEAVVVTNTIP 323
H +F+ A I +A ++ T+TIP
Sbjct: 246 HAVFAHGAQDAILSAGAARIITTDTIP 272
>UniRef50_Q1GQ93 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 299
Score = 88.2 bits (209), Expect = 3e-16
Identities = 68/283 (24%), Positives = 135/283 (47%), Gaps = 10/283 (3%)
Query: 70 LGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASA 129
LG ++G++ T++F + ET + + V G D+ +V + + L+ LLI +A + A
Sbjct: 23 LGGEVGRIETRRFPDGETYLRLLSEVAGRDIVLVCT-LDRPDTKLVSLLIAADAARELGA 81
Query: 130 SRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHA---SQIQGFFD 186
V V P Y RQD++ ++ I+++ A +S D ++T D H + + +D
Sbjct: 82 FSVGLVAPYLAYMRQDRRFQNGEAISSRSFARRIS-GAVDWLVTADPHLHRYASLGDIYD 140
Query: 187 IPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKA 246
I + + A + WI+ ++ + +++ PD+ + ++IA R A+ K R
Sbjct: 141 IRAEAVHAAAPISDWIRTHV---ERPLIIGPDSESEQWASAIARRAGAPHAVCSKLRLGD 197
Query: 247 NEVA-SMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAI 305
+V ++ + RT +LVDD+A + T+ AA + EAG ++ H +F+ A
Sbjct: 198 RDVRIALPDLSAHTGRTPVLVDDIASSARTLIEAARGIGEAGFPPPECVIVHPLFARGAF 257
Query: 306 SRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVR 348
+ + +A +V T+ + + + V +LA+ R
Sbjct: 258 AAL-SAEAGRIVSTDAVAHSSNAISLQPVVAEGVQRLLAKPDR 299
>UniRef50_Q2SLU9 Cluster: Phosphoribosylpyrophosphate synthetase;
n=1; Hahella chejuensis KCTC 2396|Rep:
Phosphoribosylpyrophosphate synthetase - Hahella
chejuensis (strain KCTC 2396)
Length = 290
Score = 87.0 bits (206), Expect = 7e-16
Identities = 63/268 (23%), Positives = 122/268 (45%), Gaps = 11/268 (4%)
Query: 59 HPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELL 118
HP +A+++ G+D+G ++F + ET + I + + S + ++ +L
Sbjct: 10 HP-VAERLAAAPGMDVGNYQLRQFPDGETYIRIEGEAPNKAIVCADLSSPD--QKILPVL 66
Query: 119 IMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHA 178
+ + +T V P PY RQD + IT++ A ++S D ++T+D H
Sbjct: 67 LFAATLRDLGVEHITLVAPYLPYMRQDIRFHPGEGITSRYFARMISAH-FDRLLTVDPHL 125
Query: 179 SQ---IQGFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVE 235
+ + + IP +L A PA+ WI+ ++ ++V PD+ + V+ +A+ +
Sbjct: 126 HRYHSLDELYSIPARSLAAAPAIADWIRTHLDK---PVIVGPDSESDQWVSHVAELAGCD 182
Query: 236 FALIHKERKKANEVASMVLVGD-VKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAI 294
+ K R +V + ++ + ++VDD+ T T+ AA +L AG + I
Sbjct: 183 RLVFSKTRLGDKDVIIDARNAEKYREYSPVMVDDIISTGRTMIEAAAELAAAGLHQPVCI 242
Query: 295 LTHGIFSGPAISRINNACLEAVVVTNTI 322
H +F+ A I A + V NT+
Sbjct: 243 GVHAVFADDAYHAIQAAPIARTVSCNTV 270
>UniRef50_A2X0F3 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Oryza sativa|Rep: Ribose-phosphate pyrophosphokinase -
Oryza sativa subsp. indica (Rice)
Length = 330
Score = 86.2 bits (204), Expect = 1e-15
Identities = 43/89 (48%), Positives = 60/89 (67%)
Query: 107 SGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVS 166
S EI L L IN + ASA +TAVIP F YAR D+K + R I AKLVAN+++ +
Sbjct: 110 SQEIASYLGLELGKINIKRRASAKNITAVIPYFGYARADRKSQGRESIAAKLVANMITEA 169
Query: 167 GADHIITMDLHASQIQGFFDIPVDNLFAE 195
GA+ ++ DLH+SQ G+FDIPVD+++ +
Sbjct: 170 GANRVLVCDLHSSQAMGYFDIPVDHVYGQ 198
Score = 78.2 bits (184), Expect = 3e-13
Identities = 44/123 (35%), Positives = 69/123 (56%), Gaps = 17/123 (13%)
Query: 252 MVLVGDVKDRTAILVDDMADTC----------------GTICHAAEKLIEAGATKVYAIL 295
M L+GDV+ + A+++DDM DT GTI AE L + GA +VYA
Sbjct: 200 MNLIGDVRGKVAVMMDDMIDTADISLPNINILMKPIKLGTIAKGAELLHQEGAREVYACC 259
Query: 296 THGIFSGPAISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRTHNGES 355
TH +FS PAI R+++ + V++TNTIP + + P++ + V+ +L E + R H+ S
Sbjct: 260 THAVFSPPAIERLSSGLFQEVIITNTIPLKED-KSFPQLTILSVANLLGETIWRVHDDCS 318
Query: 356 VSY 358
V +
Sbjct: 319 VGH 321
Score = 36.7 bits (81), Expect = 0.95
Identities = 13/31 (41%), Positives = 25/31 (80%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKK 81
+++FSG+++P L+Q+I LG++LGK+ K+
Sbjct: 98 LRIFSGTANPSLSQEIASYLGLELGKINIKR 128
>UniRef50_A4XET1 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Ribose-phosphate pyrophosphokinase - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 298
Score = 84.6 bits (200), Expect = 4e-15
Identities = 81/288 (28%), Positives = 136/288 (47%), Gaps = 21/288 (7%)
Query: 70 LGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASA 129
LGI V +F + E+ V + R IV + N L+ELL+ A + A
Sbjct: 24 LGIPALPVEVHRFPDGESRVRLHPPAR---TAIVLRPLNDPNARLIELLLAAAALRDGGA 80
Query: 130 SRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFD--- 186
+RV V P Y RQD + ++ +++ N+++ D +IT+D H ++ +
Sbjct: 81 ARVILVAPYLGYMRQDMAFRPGEAVSQRVIGNLIAAH-FDGLITVDPHLHRVSSLAEVAP 139
Query: 187 -IPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKK 245
IP ++ A P + + + D +T ++V PD+ V SIA L ++ L+ ++ +
Sbjct: 140 GIPALSISAAPVLAAELAPGL-DPRT-VLVGPDSESRPWVESIASPLGLD-VLVGEKVRH 196
Query: 246 ANEVASMVLVGD--VKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGP 303
+ + L G + R AILVDD+ + T+ A L AGAT V A+ THG+
Sbjct: 197 GDRAVRIELPGKEALHGRPAILVDDVISSGTTLIECARILRAAGATSVEAVATHGLARMQ 256
Query: 304 AISRINNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRTH 351
+ RI A + V T++I H P ++ +LA+A+RR H
Sbjct: 257 DLQRIAAAGVFRVRTTDSI--AAHPGSIP------LAPILAQALRRQH 296
>UniRef50_Q89QK8 Cluster: Bll3116 protein; n=5;
Bradyrhizobiaceae|Rep: Bll3116 protein - Bradyrhizobium
japonicum
Length = 306
Score = 84.2 bits (199), Expect = 5e-15
Identities = 66/268 (24%), Positives = 125/268 (46%), Gaps = 10/268 (3%)
Query: 61 DLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIM 120
+ A+++ RLG+ ++ +F + E V + + D I+ + + ND L+ LL
Sbjct: 14 EAAKRLAARLGLASDEMTLHRFPDGELRVTVAPAA---DTTILYAALDQPNDKLIALLFA 70
Query: 121 INACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQ 180
A + A R+ V P Y RQD + I+ + + +L+ D ++T+D H +
Sbjct: 71 AEALRRGGAKRLVLVAPYLCYMRQDIAFHAGEAISQRAMGTLLATI-VDRVVTVDAHLHR 129
Query: 181 IQG----FFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEF 236
F I +NL A PA+ + D T +V+ PDA V +A RL+++
Sbjct: 130 TPDIAAVFPGIEAENLSAMPAIANALVAAGIDPAT-VVIGPDAESEPWVRDLAGRLDLQH 188
Query: 237 ALIHKERKKANEVA-SMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAIL 295
+ K R+ V + R A++VDD+ + T+ AA+ L GA+ V +++
Sbjct: 189 TVARKLRRGDRSVEIDFADAALLAGRPALMVDDIVSSGTTLMVAAKTLRAMGASAVDSVV 248
Query: 296 THGIFSGPAISRINNACLEAVVVTNTIP 323
TH +F + +A + ++ ++++P
Sbjct: 249 THALFPPAMSAAFADAGIRSIRSSDSVP 276
>UniRef50_Q6KG64 Cluster: Putative uncharacterized protein; n=2;
Enterobacteria phage Felix 01|Rep: Putative
uncharacterized protein - Enterobacteria phage Felix 01
Length = 298
Score = 82.6 bits (195), Expect = 1e-14
Identities = 60/247 (24%), Positives = 119/247 (48%), Gaps = 12/247 (4%)
Query: 86 ETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIM---INACKIASASRVTAVIPCFPYA 142
E V+ E G+ ++ + G D L L + +++ ++ T V P A
Sbjct: 42 EDFVKFTERNAGKIDNVIITVQGYDKDTLFALALAKDAVDSLVPQKSAMKTVVFGFLPNA 101
Query: 143 RQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWI 202
R D+ K+ AN+++ G D + +D H++ + F ++ + + +
Sbjct: 102 RYDRHMFKGDAAALKVFANLVNAMGFDAVCALDPHSNVAENLFKC-FQSMKQKDVAVHYA 160
Query: 203 KENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERK-KANEVASMVLVGDVK-- 259
+ + D+ +V+PDAG +K++ A ++ + + K R K E+ M ++ DV
Sbjct: 161 NDPLIDY----LVAPDAGASKKIAETAKEVDKPYITMSKVRNLKTGEITGMRILDDVDLT 216
Query: 260 DRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVT 319
D+T +++DD+ D T AA+ L EAGA +V +THGIFS + ++N ++ + T
Sbjct: 217 DKTVMILDDICDGGRTFVEAAKHLREAGAKRVELYVTHGIFSKDVENLLDNG-IDHIYTT 275
Query: 320 NTIPQER 326
N++ + +
Sbjct: 276 NSLGEAK 282
>UniRef50_Q4DSS9 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=3; Trypanosoma|Rep: Ribose-phosphate
pyrophosphokinase, putative - Trypanosoma cruzi
Length = 705
Score = 82.6 bits (195), Expect = 1e-14
Identities = 54/192 (28%), Positives = 97/192 (50%), Gaps = 20/192 (10%)
Query: 52 KVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQS------ 105
++ SGS+ + I + L +F N E V + ++RG+DV+++QS
Sbjct: 273 RILSGSTSLFCEKMICEVLQCPRYPPCCNQFPNGEINVSLSRTLRGDDVFVLQSLVRCDH 332
Query: 106 -GSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILS 164
G + MEL +M++ +++SA+R+TAVIP YA + +VA +L
Sbjct: 333 LGLSH-SGTFMELALMLHTARLSSAARITAVIPYLAYADSVS--------SVAVVAELLE 383
Query: 165 VSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIP----DWKTSIVVSPDAG 220
G H+IT+D+ + Q++G F +P++N+ A +++I +++ D++ VVSP
Sbjct: 384 KMGCQHVITVDMSSEQVEGMFSVPLENISARYEFVRFIAKHLTNEGHDFRNITVVSPSGT 443
Query: 221 GAKRVTSIADRL 232
R AD L
Sbjct: 444 SVSRAKYFADAL 455
Score = 70.1 bits (164), Expect = 8e-11
Identities = 38/112 (33%), Positives = 65/112 (58%), Gaps = 3/112 (2%)
Query: 252 MVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNA 311
+ LVGDVK R I+VD D IC A KL EAGA+++ I TH I S A R+ +
Sbjct: 592 VALVGDVKGRLCIIVDTTIDEAIKICRTAWKLHEAGASRIILIATHLILSAGAEERLVKS 651
Query: 312 CLEAVVVTNTIPQERHMQE---CPKIQCIDVSMMLAEAVRRTHNGESVSYLF 360
++ +VVT+++ Q+ ++ K++ + ++ +LA A+ + H +++ LF
Sbjct: 652 PIDLIVVTDSVNQDVVFKKPLFAQKLRLLPIAPLLARAIEKMHTENTLATLF 703
>UniRef50_A6BI68 Cluster: Putative uncharacterized protein; n=2;
Clostridiales|Rep: Putative uncharacterized protein -
Dorea longicatena DSM 13814
Length = 395
Score = 81.0 bits (191), Expect = 4e-14
Identities = 81/313 (25%), Positives = 140/313 (44%), Gaps = 33/313 (10%)
Query: 81 KFSNMETCVEIGESVRGEDVYIV---------QSGSGEIN----DNLMELLIMINACKIA 127
+F + E I ESVRG+D+Y++ S +G IN D+ + L I A
Sbjct: 70 RFGSGEAKGIINESVRGKDLYLMVDVCNYNLTYSLTGNINHMSPDDHYQNLKRIIAAVGG 129
Query: 128 SASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQ----- 182
R+ ++P F Y + K SR + L L G D+IIT D H ++Q
Sbjct: 130 KGRRINVIMP-FLYESRQHKRSSRESLDCALALQELVRMGVDNIITFDAHDPRVQNAIPL 188
Query: 183 -GFFDIPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHK 241
GF I F + +L+ K+ D + +SPD G R +A+ LN++ + +K
Sbjct: 189 NGFETIRPTYQFVK-GLLRTFKDLQIDSDHMMAISPDEGATGRAIYLANVLNLDMGMFYK 247
Query: 242 ERKKANE-------VASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAI 294
R + VA L V+ + I++DDM + ++ A +L + A +++
Sbjct: 248 RRDFSRVVDGRNPIVAHEFLGSSVEGKDVIILDDMISSGDSMLDVARQLKQRKAKRIFCA 307
Query: 295 LTHGIFSGPAISRINNA----CLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRT 350
T G+F+ + + + A L+AV+ TN I Q + E P D+S +A +
Sbjct: 308 ATFGLFTN-GLEKFDQAYEEGILDAVLTTNLIYQTPELLERPYYINCDMSKYIALVIDTL 366
Query: 351 HNGESVSYLFSNV 363
++ S+S + + +
Sbjct: 367 NHDGSISSILNPI 379
>UniRef50_A4FCC2 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
Ribose-phosphate pyrophosphokinase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 165
Score = 81.0 bits (191), Expect = 4e-14
Identities = 50/150 (33%), Positives = 80/150 (53%), Gaps = 3/150 (2%)
Query: 213 IVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADT 272
+VV+PD G K A L A++ K R+ + V + LVGDV+ + ++VDDM T
Sbjct: 16 VVVAPDLGAVKLAEHCAAPLRAPVAVVRKTRQTGSTVRAEELVGDVESKPVLIVDDMIST 75
Query: 273 CGTICHAAEKLIEAGA-TKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHMQEC 331
GTI AA L+E GA + + + HG+ PA R+ L ++ VT+++ Q R
Sbjct: 76 GGTIEAAAHVLLEHGALSGITVVAAHGLLVDPAADRLAALPLRSLFVTDSLAQ-RASAAF 134
Query: 332 PKIQCIDVSMMLAEAVRRTHNGESVSYLFS 361
P ++ ++ +LA+A+ R H SV L +
Sbjct: 135 P-LEVHSIAPLLADAIGRLHQNLSVDDLLA 163
>UniRef50_Q4QIB8 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=3; Leishmania|Rep: Ribose-phosphate
pyrophosphokinase, putative - Leishmania major
Length = 836
Score = 81.0 bits (191), Expect = 4e-14
Identities = 51/162 (31%), Positives = 90/162 (55%), Gaps = 18/162 (11%)
Query: 81 KFSNMETCVEIGESVRGEDVYIVQSGSGEINDNL------MELLIMINACKIASASRVTA 134
+F+N E V + VRG+DV++VQS ++NL MEL +++++ ++A+A+R+TA
Sbjct: 368 RFANGEVSVNLQAPVRGDDVFVVQSMVALESENLSNAGALMELALLVHSAQLAAAARITA 427
Query: 135 VIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFA 194
VIP Y + A I+A VA ++ + G H+IT+D+H+ Q++G F IP+++ A
Sbjct: 428 VIPYLAYT------SNVASISA--VAEMIELVGCHHVITVDMHSDQVEGMFSIPIESASA 479
Query: 195 EPAVLKWIKENIPD----WKTSIVVSPDAGGAKRVTSIADRL 232
+++I + ++ VV+P R AD L
Sbjct: 480 MYEFVRYISNLLESEGNTFENITVVAPSGEFLGRAKEYADAL 521
Score = 79.4 bits (187), Expect = 1e-13
Identities = 41/127 (32%), Positives = 73/127 (57%), Gaps = 3/127 (2%)
Query: 237 ALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILT 296
ALI ++ +NE VLVGDVKDR I+++ + D I + A L E GA ++ + T
Sbjct: 707 ALIMRKETASNEYKKYVLVGDVKDRLCIIIESVIDEAINITNVARCLQEHGAERIILVAT 766
Query: 297 HGIFSGPAISRINNACLEAVVVTNTIPQERHMQE---CPKIQCIDVSMMLAEAVRRTHNG 353
H + SG AI + + +E V+VT+++ Q+ M+ K++ + ++ +LA A+ + H
Sbjct: 767 HAVMSGKAIHLLVESPIELVLVTDSVNQDELMKNPALARKLRVVPIAPLLARAIEKIHTE 826
Query: 354 ESVSYLF 360
+++ LF
Sbjct: 827 NTLATLF 833
>UniRef50_A1HDW3 Cluster: Ribose-phosphate diphosphokinase; n=3;
Ralstonia|Rep: Ribose-phosphate diphosphokinase -
Ralstonia pickettii 12J
Length = 313
Score = 80.6 bits (190), Expect = 6e-14
Identities = 70/257 (27%), Positives = 116/257 (45%), Gaps = 9/257 (3%)
Query: 70 LGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASA 129
L +LG F + E+ V + V G +V IV + ++ L+ LL + A + A
Sbjct: 31 LRAELGHAAVTHFPDGESYVRLYTPVHGAEVAIVCT-LDHPDEKLLPLLWLAIAARQGGA 89
Query: 130 SRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHA---SQIQGFFD 186
RV + P PY RQD + A+ A +L+ D ++T+D H S++ +
Sbjct: 90 RRVGLIAPYLPYMRQDVIFNAGEIRAAEHFAALLNPV-FDWLVTVDPHLHRISRLSEVYR 148
Query: 187 IPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKA 246
+P + A PA+ +WI+ ++ + ++ PD + V +A +A + K R A
Sbjct: 149 VPTVAVEAAPAIAEWIQTHV---QAPFLIGPDEESRQWVEQVAGMCGAPWAALTKTRHSA 205
Query: 247 NEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAIS 306
V L +LVDD+ T T+ AA L AG + + H +F+ A S
Sbjct: 206 WHVEVTELPNIPPRCVPVLVDDIISTGRTMLAAAGLLQRAGKPQPVCVGVHAVFAADAYS 265
Query: 307 RINNACLEAVVVTNTIP 323
++ A E VV +TIP
Sbjct: 266 QLCAASAE-VVTCDTIP 281
>UniRef50_Q93Z66 Cluster: Ribose-phosphate pyrophosphokinase 3; n=9;
Magnoliophyta|Rep: Ribose-phosphate pyrophosphokinase 3
- Arabidopsis thaliana (Mouse-ear cress)
Length = 411
Score = 79.8 bits (188), Expect = 1e-13
Identities = 69/257 (26%), Positives = 120/257 (46%), Gaps = 14/257 (5%)
Query: 53 VFSGSSHPDLAQKIVDRLG-IDLGKVVTKKFSN--METCVEIGESVRGEDVYIVQSGSGE 109
+F DLA++IV + I+L + KKF + ++ + +RG+ V + S S
Sbjct: 103 LFHSDETRDLAERIVAKSDCIELRSINWKKFDDGFPNLFIQNAQGIRGQHVAFLASFSSP 162
Query: 110 INDNLMELLIMINACKIASASRVTAVIPCFPYAR----QDKKDKSRAPITAKLVANI-LS 164
+ E L +I A S T V+P FP +D+ D + A A++++NI S
Sbjct: 163 AV--IFEQLSVIYALPKLFVSSFTLVLPFFPTGTSERMEDEGDVATAFTLARILSNIPTS 220
Query: 165 VSGADHIITMDLHASQIQGFFDIPVDNLFAEPA-VLKWIKENIPDWKTSIVVSPDAGGAK 223
G ++T D+HA Q + +F + F +LK +++PD + PD G K
Sbjct: 221 RGGPTSLVTFDIHALQERFYFGDTILPCFESGIPLLKSRLQSLPDSDNISIAFPDDGAWK 280
Query: 224 RVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKL 283
R +L ++ + + ++ + GD + R ++VDD+ + GT+ + L
Sbjct: 281 RFHK---QLQHYPTIVCNKVRMGDKRIVRIKEGDAEGRHVVIVDDLVQSGGTLIECQKVL 337
Query: 284 IEAGATKVYAILTHGIF 300
GA K+ A +THGIF
Sbjct: 338 AAHGAAKISAYVTHGIF 354
>UniRef50_Q1FFM9 Cluster: Ribose-phosphate pyrophosphokinase; n=8;
Clostridiales|Rep: Ribose-phosphate pyrophosphokinase -
Clostridium phytofermentans ISDg
Length = 390
Score = 79.4 bits (187), Expect = 1e-13
Identities = 72/307 (23%), Positives = 136/307 (44%), Gaps = 32/307 (10%)
Query: 81 KFSNMETCVEIGESVRGEDVYIVQSGSGEIN--------------DNLMELLIMINACKI 126
+F E I E++RG D++++ + N D+ +L +I A KI
Sbjct: 67 RFGTGEAKAVINETIRGCDLFLIADVTNYTNHYMMFGEDSMKSPDDHFQDLKRVIAAAKI 126
Query: 127 ASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFD 186
+ RV ++P RQ +DK + A + LS G ++IIT D H +IQ
Sbjct: 127 SKVKRVNVILPFLYEGRQHHRDKLESLDCANALQE-LSEMGVENIITFDAHDPRIQNAIP 185
Query: 187 IP-VDNLFAEPAVLKWI----KENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHK 241
I DN + ++ + K+ + D +V+SPD GG R A+ L VE + +K
Sbjct: 186 IRGFDNFYTSLQFIRELLFIEKDLVIDKDHLMVISPDEGGMTRAVYYANVLGVEMGMFYK 245
Query: 242 ERKKA------NEVASMVLVG-DVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAI 294
R + N + + +G ++ + +VDD+ + +I A++L A +V+
Sbjct: 246 RRDYSTIIDGRNPIVAHEFLGSSLEGKDVFIVDDIISSGDSIIDVAKELKRRKAGRVFIA 305
Query: 295 LTHGIFSGPAISRINN----ACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRRT 350
T G+F + R++ ++ + TN + + + P + +D+S ++ V
Sbjct: 306 ATFGLFCN-GLERVDEYYEAGYIDRIYTTNLVYNNEELLKRPYYRNVDLSRYISLIVDTL 364
Query: 351 HNGESVS 357
++ SV+
Sbjct: 365 NHDTSVN 371
>UniRef50_Q21W91 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 301
Score = 78.2 bits (184), Expect = 3e-13
Identities = 69/266 (25%), Positives = 123/266 (46%), Gaps = 14/266 (5%)
Query: 63 AQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMIN 122
A +I G L ++ +F + E + + ++ D ++ + N+ L+ELL+
Sbjct: 17 AARIAQVAGHHLVRIDRHRFPDGELKLRLPPTL--PDHVVILRTLNDPNEKLVELLLTAQ 74
Query: 123 ACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQ 182
+ A +T V P Y RQD + I+ ++V L+ D +IT+D H ++
Sbjct: 75 TARDLGARHLTLVAPYLGYMRQDVAFQPGEAISQRIVGRFLA-GLFDAVITVDPHLHRVA 133
Query: 183 GFFD-IPVDN---LFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFAL 238
+PV N L A P + I P ++++ PD A+ + A R ++A+
Sbjct: 134 TLQQAVPVANAVVLSAAPLLSDLIVTQRPK---ALLLGPDEESAQWLALAASRHGFDYAV 190
Query: 239 IHKERK--KANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILT 296
K R+ +A ++A ++ V R +L+DD+ T T+ A +L+ AGA V +T
Sbjct: 191 CRKVRRGDRAVDIALPDIL--VSGRQVVLLDDVVSTGHTLAQATRQLLAAGAASVDVAVT 248
Query: 297 HGIFSGPAISRINNACLEAVVVTNTI 322
H +F G A I NA + V T+ +
Sbjct: 249 HALFVGDAWQMILNAGVREVWSTDCV 274
>UniRef50_A7B5K6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus gnavus ATCC 29149|Rep: Putative
uncharacterized protein - Ruminococcus gnavus ATCC 29149
Length = 420
Score = 77.4 bits (182), Expect = 5e-13
Identities = 64/246 (26%), Positives = 113/246 (45%), Gaps = 26/246 (10%)
Query: 81 KFSNMETCVEIGESVRGEDVYIVQ---------SGSGEIN----DNLMELLIMINACKIA 127
+F + E I E++RG D++I+ S +G +N D+ + + + A
Sbjct: 98 RFGSGEAKGVIKETIRGTDLFIMSDVCNYSLTYSVNGHLNHMSPDDHFQDIKRVIAASTG 157
Query: 128 SASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDI 187
A RV ++P +RQ K+ K R + L L G +I+T D H ++Q +
Sbjct: 158 KAHRVNVIMPFLYESRQHKRTK-RESLDCALALEELKDMGVANILTFDAHDPRVQNAIPL 216
Query: 188 P-VDNLFAEPAVLKWIKENIPDWKTS----IVVSPDAGGAKRVTSIADRLNVEFALIHKE 242
DN + +K + +PD K S ++VSPD G R ++ L V+ + +K
Sbjct: 217 SGFDNFTPQYQFMKALFRAVPDLKVSKDHLMIVSPDEGAMHRAVYFSNVLGVDMGMFYKR 276
Query: 243 RKKA------NEVASMVLVGD-VKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAIL 295
R + N + + +GD V + I+VDDM + ++ A+KL + A +V+
Sbjct: 277 RDYSTIVNGKNPIVAHEFLGDDVAGKDVIIVDDMISSGESMLDVAKKLKDRNAARVFVCT 336
Query: 296 THGIFS 301
T G+F+
Sbjct: 337 TFGLFT 342
>UniRef50_Q97KU7 Cluster: Phosphoribosylpyrophosphate synthetase;
n=5; Clostridium|Rep: Phosphoribosylpyrophosphate
synthetase - Clostridium acetobutylicum
Length = 371
Score = 75.4 bits (177), Expect = 2e-12
Identities = 70/308 (22%), Positives = 142/308 (46%), Gaps = 35/308 (11%)
Query: 81 KFSNMETCVEIGESVRGEDVYI---------------VQSGSGEINDNLMELLIMINACK 125
+FSN E V++ ESVRG+D+YI +++ G +++ ++ ++A +
Sbjct: 50 RFSNGEGKVKLSESVRGKDIYILCDVGNYSCTYNMFGIENHKGP-DEHFQDIKRTVSAIR 108
Query: 126 IASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFF 185
A R+T ++P +RQ ++ K R + L L G ++T D H +Q
Sbjct: 109 -GKARRITVIMPLLYESRQHRR-KGRESLDCALALQELERLGVQEVLTFDAHDPNVQNAI 166
Query: 186 DI-PVDNLFAEPAVLKWI---KENIPDWKTS-IVVSPDAGGAKRVTSIADRLNVEFALIH 240
+ +NL+ ++K I ++NI K S +V+SPD G R + L V+ L +
Sbjct: 167 PLMSFENLYPTYDIVKTIIMEEKNIEVNKNSMLVISPDTGAMDRAIYYSSVLGVDVGLFY 226
Query: 241 KERKKA------NEVASMVLVG-DVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYA 293
K R + N + +G DV+++ ++VDDM + ++ A++L A +Y
Sbjct: 227 KRRDHSTIVNGKNPIVKHEYMGRDVENQDVLIVDDMIASGESVLDIAKELKARKARNIYV 286
Query: 294 ILTHGIFSGPAISRI----NNACLEAVVVTNTIPQERHMQECPKIQCIDVSMMLAEAVRR 349
T F+ + + ++ + V TN +++ + +D+S +++ + +
Sbjct: 287 ATTFAFFT-EGLEKFQKYYDDNIISRVYSTNLTYIPPELEKTEWFRKVDMSELISRIIHK 345
Query: 350 THNGESVS 357
+ ES++
Sbjct: 346 LNKDESIA 353
>UniRef50_UPI00004989B9 Cluster: ribose-phosphate pyrophosphokinase;
n=2; Entamoeba histolytica HM-1:IMSS|Rep:
ribose-phosphate pyrophosphokinase - Entamoeba
histolytica HM-1:IMSS
Length = 337
Score = 74.1 bits (174), Expect = 5e-12
Identities = 76/303 (25%), Positives = 145/303 (47%), Gaps = 23/303 (7%)
Query: 63 AQKIVDRLGIDLGKVVTKKFSNMET----CVEIGESVRGEDVYIVQSGSGEINDNLMELL 118
A + ++L + V+ K+FS+ E ++ S+ G+DV IV S + L+EL+
Sbjct: 20 ADLLAEKLRYPILPVIRKQFSDGELYYKFTIQNKTSLIGKDVLIVCSMVDD--QELLELI 77
Query: 119 IM-INACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILS---VSGADHI-IT 173
+ + ++ + RV VIP Y ++ +T K +LS G ++ +
Sbjct: 78 RLGLELSELGTRRRVF-VIPYLLYQTMNRASLPGEVVTCKSTVRMLSSISTCGLGNLYLL 136
Query: 174 MDLHASQIQGFFD-IPVDNLFAEPAVLKWIKENIPDWKTSIVV--SPDAGGAKRVTSIAD 230
+DLH S I +F+ L+A+ + I + + D++ VV + D G K V + ++
Sbjct: 137 LDLHTSGIIHYFEKTQAMELYAQKPLYNAIAKEV-DFQNEDVVFGTTDLGRPKWVETYSN 195
Query: 231 RLNVEFALIHKERKKANEVASMVL---VGDVKDRTAILVDDMADTCGTICHAAEKLIEAG 287
V L R+ NE + ++ +G+ K + +L DD+ + T AAE + G
Sbjct: 196 LFGVGIVLCRAPRE-LNENSPEIMKEPIGECKGKHVVLYDDIIRSGKTAIAAAENYLRHG 254
Query: 288 ATKVYAILTH-GIFSGPAISRINNACLEAVVVTNT--IPQERHMQECPKIQCIDVSMMLA 344
ATKV +++H + I R+ + ++ +++TN+ Q ++ C KI+ +DVS +
Sbjct: 255 ATKVTCVISHFAVTKESIIQRLEQSPIDKIIITNSHINSQLLAVKLCKKIRIVDVSCVFV 314
Query: 345 EAV 347
E +
Sbjct: 315 EQI 317
>UniRef50_Q7XZ65 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=1; Griffithsia japonica|Rep: Phosphoribosyl
pyrophosphate synthetase - Griffithsia japonica (Red
alga)
Length = 92
Score = 72.1 bits (169), Expect = 2e-11
Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 1/85 (1%)
Query: 279 AAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQERHM-QECPKIQCI 337
AA L E GA V A H + SGPA+ RIN +C++ +V+TN+I M ++ P + +
Sbjct: 7 AAVALSENGAKSVRACCIHAVLSGPAVDRINASCIKELVITNSIAHSEEMRKKLPCLTTL 66
Query: 338 DVSMMLAEAVRRTHNGESVSYLFSN 362
+ ++AE +RR H ESVS LF N
Sbjct: 67 SIGNVMAETIRRVHREESVSTLFDN 91
>UniRef50_A2FWD0 Cluster: Ribose-phosphate pyrophosphokinase family
protein; n=2; Trichomonas vaginalis G3|Rep:
Ribose-phosphate pyrophosphokinase family protein -
Trichomonas vaginalis G3
Length = 327
Score = 70.9 bits (166), Expect = 5e-11
Identities = 57/229 (24%), Positives = 103/229 (44%), Gaps = 10/229 (4%)
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
+D+++E+ + + R +IP Y+ ++ +TAK +LS G+
Sbjct: 71 DDDILEVYRVGSTLVQYGVRRRVFIIPFLGYSTMERAVLPGEVVTAKCTIQMLSSIGSGS 130
Query: 171 ----IITMDLHASQIQGFFDIPVDNL--FAEPAVLKWIKENIPDWKTSIVVSPDAGGAKR 224
+ DLH + + +F+ P L + + A+LK + D T + S D G
Sbjct: 131 NGNVFLLFDLHTAGLLHYFEGPCLRLELYGQKALLKSLPLIGFDPATFMFASADLGRTAW 190
Query: 225 VTSIADRLNVEFALIHKERKKANEVA---SMVLVGDVKDRTAILVDDMADTCGTICHAAE 281
V + A A I K R ++ + ++GDVK + ++ DDM + GT+ HAAE
Sbjct: 191 VNAFARESGTPVAFIRKVRTMVGSISQSQAFEVIGDVKGKHVVIYDDMTRSGGTLVHAAE 250
Query: 282 KLIEAGATKVYAILTHGIFSG-PAISRINNACLEAVVVTNTIPQERHMQ 329
K + GA V ++H + + ++ + N+ L +V NT P + Q
Sbjct: 251 KYLSVGALSVDVCVSHFLPNDKKVLNYLINSPLRKIVALNTHPATQTAQ 299
>UniRef50_Q4FCY7 Cluster: Phosphoribosyl pyrophosphate synthetase
2; n=2; Bovinae|Rep: Phosphoribosyl pyrophosphate
synthetase 2 - Bos taurus (Bovine)
Length = 82
Score = 69.3 bits (162), Expect = 1e-10
Identities = 33/54 (61%), Positives = 41/54 (75%), Gaps = 3/54 (5%)
Query: 37 KLDHVLPLTT---RMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMET 87
+L PL T MPNI +FSGSSH DL+Q++ DRLG++LGKV+TKKFSN ET
Sbjct: 29 RLSRPAPLGTPRPTMPNIVLFSGSSHQDLSQRVADRLGLELGKVITKKFSNQET 82
>UniRef50_Q8KTQ3 Cluster: Phosphoribosylpyrophosphate synthetase;
n=4; Candidatus Tremblaya princeps|Rep:
Phosphoribosylpyrophosphate synthetase - Tremblaya
princeps
Length = 199
Score = 68.5 bits (160), Expect = 3e-10
Identities = 53/174 (30%), Positives = 95/174 (54%), Gaps = 17/174 (9%)
Query: 56 GSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLM 115
G+ LA++I GI +G + ++++ E +I ++VR D ++ + +N ++
Sbjct: 8 GTGTIGLARRISRHCGIRVGLMECGRYADGERYGDIAQNVRNNDELLLHTLCSPVN-SIG 66
Query: 116 ELLIMINACKIASASRVTAVIPCFPYARQDKKDK-SRAPITAKLVANILSVSGADHIITM 174
E+++ A AS VT V+P Y RQ+K + +RA ++A+ VA++LS +++ M
Sbjct: 67 EIIL-------AQASGVTLVLPYVAYGRQEKHAQGTRATLSARCVASVLS----RNLVAM 115
Query: 175 DLHASQIQGFFDIPVDNLFAEPAVLKWIKENIP-DWKTSIVVSPDAGGAKRVTS 227
DLH S+ FFD+P L A ++ +P +++ VSPDAGGA V +
Sbjct: 116 DLHLSKRHVFFDVPTQLLSMRHAFDEY---RLPGSARSTARVSPDAGGAMDVVT 166
>UniRef50_Q11SD6 Cluster: Phosphoribosylpyrophosphate synthetase;
n=2; Bacteroidetes|Rep: Phosphoribosylpyrophosphate
synthetase - Cytophaga hutchinsonii (strain ATCC 33406 /
NCIMB 9469)
Length = 289
Score = 68.5 bits (160), Expect = 3e-10
Identities = 57/225 (25%), Positives = 96/225 (42%), Gaps = 12/225 (5%)
Query: 82 FSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPY 141
FS E ++I V V ND + LL+ ++A + ++ IP FP
Sbjct: 34 FSGGEPHIKIRPDVDTNQPITVTHRLNSFNDVGL-LLVAVDALRRMHVDKINLFIPYFPA 92
Query: 142 ARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFD--IPVDNLFAEPAVL 199
ARQD+ P+T K+ A +++ + D H+ + V N VL
Sbjct: 93 ARQDRVMVKGEPLTVKVYAELINALQLSKVTVFDAHSEVTPALLNNCEAVSNHRFIQQVL 152
Query: 200 KWIKENIPDWKTSIVVSPDAGGAKRVTSIADRL-NVEFALIHKERKKANEVAS--MVLVG 256
K I N +++SPD G K++ +++ L ++ K R V
Sbjct: 153 K-ITGN-----DCLLISPDGGALKKIYKVSEYLGGIQVVECSKSRDVTTGKLKGFKVYAD 206
Query: 257 DVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFS 301
D++ + ++VDD+ D GT AE+L + +Y ++HGIFS
Sbjct: 207 DLQGKDCLIVDDICDGGGTFIGLAEELKKKNCGAIYLAVSHGIFS 251
>UniRef50_Q6FDK1 Cluster: Putative ribose-phosphate
pyrophosphokinase; n=2; Acinetobacter|Rep: Putative
ribose-phosphate pyrophosphokinase - Acinetobacter sp.
(strain ADP1)
Length = 293
Score = 65.7 bits (153), Expect = 2e-09
Identities = 59/242 (24%), Positives = 116/242 (47%), Gaps = 33/242 (13%)
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH 170
+D++++ L++ N I + IP FPYARQD+ + + + ++L+++ H
Sbjct: 49 SDDILDYLLLENVL-IQHRKNIEVEIPYFPYARQDRVCATGQAFSLDVFCHLLNINIEKH 107
Query: 171 I-----ITM-DLHASQI----QGF---FDI----PVDNLFAEPAVLKWIKENIPDWKTSI 213
IT+ D H++ I G+ D+ PV+ + PA+ + +++ + ++
Sbjct: 108 TSIRRRITLWDAHSNVIGQLLNGYSSHLDLYQVEPVEIIKTSPALTELLQQ-----QHTV 162
Query: 214 VVSPDAGGAKRVTSIADRLNV----EFALIH----KERKKANEVASMVLVGDVKDRTAIL 265
+V PD G R +IA N + A+IH +E +S+V G + +TA++
Sbjct: 163 LVCPDRGAKARTAAIAQYFNPKRSQQIAIIHCDKTREPTTGKITSSVVKTGSLAGKTAVI 222
Query: 266 VDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIPQE 325
DD+ D T A++L + + +THGIFS + + ++ + +N+ PQ+
Sbjct: 223 TDDICDGGATFIGIAKELRKLQCEHIILYVTHGIFSRGL--DVFDGLIDQIFTSNSRPQQ 280
Query: 326 RH 327
H
Sbjct: 281 FH 282
>UniRef50_A6LV64 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
Ribose-phosphate pyrophosphokinase - Clostridium
beijerinckii NCIMB 8052
Length = 266
Score = 65.7 bits (153), Expect = 2e-09
Identities = 70/261 (26%), Positives = 118/261 (45%), Gaps = 20/261 (7%)
Query: 76 KVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAV 135
++ KKF N E+ + E E V ++ ND + LI + + +
Sbjct: 8 EIEVKKFPNGESLINSQELNIKEWVNTIKLKFESDND--ITHLIFLKDHLDELNIKCNLI 65
Query: 136 IPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFD-IPVDNLFA 194
IP PY+R D+ + T K + +++ + + + H+ D + V N+ A
Sbjct: 66 IPYMPYSRMDRTEGFTV-FTLKHLCRLINNLNFEEVSIYEPHSDVCVALLDRVKVINMSA 124
Query: 195 EPAVLKWIKENIPDWKTSI-VVSPDAGGAKRVTSIADRLNVEFALI-HKERK-KANEVAS 251
+ K + E + D K S+ +V PDAG AKR ++ E L +KER K +
Sbjct: 125 --ILAKNLLEKVDDKKDSVYLVYPDAGAAKRY---GKQIQYEKILTANKERDFKTGFINK 179
Query: 252 MVLVGDVKDRT--AILVDDMADTCGTICHAAEKLIEAGATKVYAILTH---GIFSGPAIS 306
+ + G V+ + AI+VDD+ GT A+KL E GAT++Y ++TH IF G
Sbjct: 180 LEINGTVESKKFKAIIVDDLCSKGGTFILTAKKLKEMGATEIYLVVTHCEDTIFDGEI-- 237
Query: 307 RINNACLEAVVVTNTIPQERH 327
+ + V T++I + H
Sbjct: 238 -LKTDLITKVFTTSSILSKEH 257
>UniRef50_Q680A5 Cluster: Ribose-phosphate pyrophosphokinase 4;
n=13; Viridiplantae|Rep: Ribose-phosphate
pyrophosphokinase 4 - Arabidopsis thaliana (Mouse-ear
cress)
Length = 337
Score = 65.7 bits (153), Expect = 2e-09
Identities = 54/211 (25%), Positives = 101/211 (47%), Gaps = 9/211 (4%)
Query: 95 VRGEDV-YIVQSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKK-DKSRA 152
+RG+ V ++ S + + ++ ++ +AS + V P + R +++ D + A
Sbjct: 75 IRGQHVAFLASFSSPAVIFEQISVIYLLPRLFVASFTLVLPFFPTGSFERMEEEGDVATA 134
Query: 153 PITAKLVANI-LSVSGADHIITMDLHASQIQGFFDIPVDNLFAE--PAVLKWIKENIPDW 209
A++V+NI +S G ++ D+HA Q + +F V LF P + K +++ +P+
Sbjct: 135 FTMARIVSNIPISRGGPTSVVIYDIHALQERFYFADQVLPLFETGIPLLTKRLQQ-LPET 193
Query: 210 KTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDM 269
+ IV PD G KR + D + K R+ + + G+ ++VDD+
Sbjct: 194 EKVIVAFPDDGAWKRFHKLLDHYPT--VVCTKVREGDKRIVRLK-EGNPAGCHVVIVDDL 250
Query: 270 ADTCGTICHAAEKLIEAGATKVYAILTHGIF 300
+ GT+ + L GA KV A +THG+F
Sbjct: 251 VQSGGTLIECQKVLAAHGAVKVSAYVTHGVF 281
>UniRef50_Q7P228 Cluster: Probable ribose-phosphate diphosphokinase;
n=1; Chromobacterium violaceum|Rep: Probable
ribose-phosphate diphosphokinase - Chromobacterium
violaceum
Length = 270
Score = 62.9 bits (146), Expect = 1e-08
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 13/173 (7%)
Query: 136 IPCFPYARQDKKDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFD-IPVDNLFA 194
+P PYARQD+ ++AK+ +++ G + D H+ + D + V++
Sbjct: 76 LPYVPYARQDRVANPGEALSAKVFCGLINQQGYSRVRIQDPHSDVVTALLDRVEVEDPL- 134
Query: 195 EPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKK-ANEVASMV 253
PA+ + ++ P + +V+PDAG KRV +A +L K R +++ +
Sbjct: 135 -PALRRALEAIGP----ATLVAPDAGARKRVLKLAQQLGCGAVCADKARDTVTGKISGIE 189
Query: 254 LVGDVKDRTAILVDDMADTCGTICHAAEKL-----IEAGATKVYAILTHGIFS 301
+ G + ++VDD+ D GT AE + E + +Y +THGIFS
Sbjct: 190 VHGALPAGPLLVVDDICDGGGTFVGLAEAIAARQAAEGQSAPLYLYVTHGIFS 242
>UniRef50_Q0U4M2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 89
Score = 62.9 bits (146), Expect = 1e-08
Identities = 31/55 (56%), Positives = 36/55 (65%)
Query: 53 VFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGS 107
VF+GSSHP L + I DRLG G KF N ET V I S+R +DV+IVQSGS
Sbjct: 28 VFAGSSHPKLVEGICDRLGTKQGSATLGKFKNGETSVTIHTSIRNKDVFIVQSGS 82
>UniRef50_Q64M76 Cluster: Phosphoribosyl pyrophosphate
synthase-like; n=2; Oryza sativa|Rep: Phosphoribosyl
pyrophosphate synthase-like - Oryza sativa subsp.
japonica (Rice)
Length = 183
Score = 61.3 bits (142), Expect = 4e-08
Identities = 31/72 (43%), Positives = 52/72 (72%), Gaps = 7/72 (9%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
+++FSG+++P LAQ++ LG++LG+V K+F++ G SVRG D+++VQ+
Sbjct: 104 LRIFSGTANPTLAQEVAFYLGMELGRVKIKRFTD-------GGSVRGCDMFLVQATCPPP 156
Query: 111 NDNLMELLIMIN 122
N+N+MELLIMI+
Sbjct: 157 NENMMELLIMID 168
>UniRef50_Q8EFJ2 Cluster: Phosphoribosyl transferase domain protein;
n=4; Shewanella|Rep: Phosphoribosyl transferase domain
protein - Shewanella oneidensis
Length = 301
Score = 60.9 bits (141), Expect = 5e-08
Identities = 47/190 (24%), Positives = 89/190 (46%), Gaps = 11/190 (5%)
Query: 113 NLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPITAKLVANILSVSGADHII 172
++M+LL++ +A + A ++ ++P P ARQD+ ++ K+ A++++ +
Sbjct: 72 SIMQLLLLTDALRRNGAEQIDLLLPYMPGARQDRVCNVGEALSVKVYASLINQQQYASVS 131
Query: 173 TMDLHASQIQGFFD--IPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIAD 230
D H+ D +DN A+ + + ++VSPDAG K+V +A
Sbjct: 132 VFDPHSDVTAALLDRVQVIDNHSFVAAIAAQLTGEL------VLVSPDAGANKKVFGLAK 185
Query: 231 RLN---VEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAG 287
L V A H++ + +A+ V D+ +T ++VDD+ T A KL +
Sbjct: 186 ALQGMPVIRADKHRDVVNGHIIATEVFCDDLSGKTCLIVDDICAGGRTFIELAIKLKQKR 245
Query: 288 ATKVYAILTH 297
A V I++H
Sbjct: 246 AQSVILIVSH 255
>UniRef50_A6DTG6 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Ribose-phosphate
pyrophosphokinase - Lentisphaera araneosa HTCC2155
Length = 390
Score = 58.8 bits (136), Expect = 2e-07
Identities = 68/278 (24%), Positives = 119/278 (42%), Gaps = 35/278 (12%)
Query: 81 KFSNMETCVE-IGESVRGEDVYIVQSGSGEINDNLMEL--LIMINACKIASASRVTAVIP 137
+F N ET E IG ++G+ V IV + S + N + + L++ A K A +V + P
Sbjct: 46 RFINDETAFEDIGYYLKGKTVVIVSTQSLTFSRNSLSMRNLVIARAAKDNGAEQVILMEP 105
Query: 138 CFPYARQDK------------------KDKSRAPITAKLVANILSVSGADHIITMDLHAS 179
Y+ QD+ K P TA L A +LS++G D T+ H+
Sbjct: 106 DLFYSCQDRGPRHEHSFFNEERSAEIRKKFDGQPFTALLYAQLLSLAGVDQAFTIHNHSF 165
Query: 180 QIQGFFDIPVDNLFAE--PAVL---KWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLN- 233
Q F ++ F P + I D +I+ +PD G V I D ++
Sbjct: 166 STQNLFQKELNGYFHNYVPCDIFSHYLASSGIVDPGKTILCAPDKGAVPFVQMIKDEMSH 225
Query: 234 VEFALIHKERKKANEVA--------SMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIE 285
+ ++ ++ ++ E A S + + D++ + I+ DDM T TI L +
Sbjct: 226 LNPPILKMDKVRSGERAIEMEPSEDSDIGMEDIEGKDVIVFDDMVRTGTTIVKCCRILKQ 285
Query: 286 AGATKVYAILTHGIFSGPAISRINNACLEAVVVTNTIP 323
++ +TH S + ++ + ++ +V TNTIP
Sbjct: 286 YKPRRIIFCVTHFHSSAESREKLADHSIDEIVTTNTIP 323
>UniRef50_A2FHP9 Cluster: Ribose-phosphate pyrophosphokinase family
protein; n=1; Trichomonas vaginalis G3|Rep:
Ribose-phosphate pyrophosphokinase family protein -
Trichomonas vaginalis G3
Length = 333
Score = 58.8 bits (136), Expect = 2e-07
Identities = 47/223 (21%), Positives = 97/223 (43%), Gaps = 11/223 (4%)
Query: 135 VIPCFPYARQDKKDKSRAPITAKLVANILSVSGADH----IITMDLHASQIQGFFD---I 187
VIP Y+ D+ + +K+ + S GA + +DLH + + +F+ +
Sbjct: 98 VIPFLAYSSNDRAISPGEVVVSKINHTLFSSLGATDEGNVFVFLDLHTAGLLHYFEGSCL 157
Query: 188 PVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKAN 247
++ L+ + A+ I D ++ +P+ +K V S A V A + +
Sbjct: 158 RIE-LYGQRALCDAIYSAGFDMSKVVIGAPNLRDSKWVNSYASEFKVPIAFVTQNSTLEE 216
Query: 248 EVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTH-GIFSGPAIS 306
+++GDV+ + I+ D+ + + + + + AGA+ V +L+H I I
Sbjct: 217 NSPGSLVIGDVQGKHVIVYSDLIRSSSAVINVTKTYLNAGASSVDFMLSHFAIVDENQIK 276
Query: 307 RINNACLEAVVVTNTIP--QERHMQECPKIQCIDVSMMLAEAV 347
I ++ + + TN+ P Q ++ PK ID++ A +
Sbjct: 277 EIADSPVSGIYATNSHPITQTELVRSSPKFHIIDIAPYFARCL 319
>UniRef50_A6VUG9 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Gammaproteobacteria|Rep: Ribose-phosphate
pyrophosphokinase - Marinomonas sp. MWYL1
Length = 403
Score = 56.0 bits (129), Expect = 1e-06
Identities = 78/331 (23%), Positives = 134/331 (40%), Gaps = 53/331 (16%)
Query: 45 TTRMPNIKVFSGSSHPDLAQKIVDRLGI--DLGKVVT-KKFSNMETCVE----------I 91
T + N+ V S SS A + +G D+ +++ K+F N E C I
Sbjct: 5 TGQATNVVVVSNSSDNPFAIDVAYAMGQHEDIADLISMKQFMNSEFCPRFISDEADFDNI 64
Query: 92 GESVRGEDVYIVQSGSG--EINDNLMELLIMINACKIASASRVTAVIPCFPYARQDK--- 146
G ++G+ V IV +GS + M LI+ A K A RV V P Y+ QD+
Sbjct: 65 GRKLKGKSVIIVSTGSHVKSRQELAMANLIIARAAKENGADRVILVEPDLFYSAQDRGPH 124
Query: 147 ---------------KDKSRAPITAKLVANILSVSGADHIITMDLHASQIQGFFD----- 186
K P TAKL A +L +SG D ++T+ H+ +Q F
Sbjct: 125 QSLGETSFERDIQDVKKFDGQPFTAKLYAQLLKLSGVDTVMTIHNHSDSVQKMFTEVFEG 184
Query: 187 -----IPVDNLFAEPAVLKWIKENIPDWKTSIVVSPDAGGAKRVTSIADRLNV---EFAL 238
IP + ++A + I D + ++ +PD G V + L + +F +
Sbjct: 185 DFHNLIPYE-IYAHYLLNSNILNYGEDGEGLVLCAPDKGARDFVKEMFKTLGLSKAKFIM 243
Query: 239 IHKERKKANEV------ASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVY 292
+ K+R +V S + + +L DDM T T+ + + L + ++
Sbjct: 244 LDKDRTAERKVEITLHKESEHTFDGLDGASIVLFDDMVRTGSTVVKSCQFLQQINPERMV 303
Query: 293 AILTHGIFSGPAISRINNACLEAVVVTNTIP 323
++H S R+ + + ++ NT+P
Sbjct: 304 FAVSHFYASDEGRERMAHPAIGEILTLNTLP 334
>UniRef50_A6MK41 Cluster: Phosphoribosyl pyrophosphate
synthetase-associated 1-like protein; n=5;
Euteleostomi|Rep: Phosphoribosyl pyrophosphate
synthetase-associated 1-like protein - Callithrix
jacchus (Common marmoset)
Length = 39
Score = 55.6 bits (128), Expect = 2e-06
Identities = 20/34 (58%), Positives = 31/34 (91%)
Query: 330 ECPKIQCIDVSMMLAEAVRRTHNGESVSYLFSNV 363
+CPKI+ +D+S++L+EA+RR HNGES++YLF N+
Sbjct: 2 QCPKIKTVDISLILSEAIRRIHNGESMAYLFRNI 35
>UniRef50_A7SHY8 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 227
Score = 54.0 bits (124), Expect = 6e-06
Identities = 48/194 (24%), Positives = 86/194 (44%), Gaps = 8/194 (4%)
Query: 158 LVANILSVSGADHIITMDLHASQIQGFF-DIPVDNLFAEPAVLKWIKENIPDWKTSIVVS 216
L A L+ G I+ D+HA Q + +F D + L + +L + N + K +I
Sbjct: 30 LSATPLTARGPTQIVIFDIHALQERFYFGDFVIPRLESAIPLLLRVLSNFQE-KVNIAF- 87
Query: 217 PDAGGAKRVTSIADRL-NVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGT 275
PD G KR ++ N+ I K+ +V K I+VDD+ T GT
Sbjct: 88 PDEGAYKRFHTMFQAFPNITCIKIRDGDKRIVKVKEGKFTP--KGSHVIIVDDLVMTGGT 145
Query: 276 ICHAAEKLIEAGATKVYAILTHGIFSGPAISRI--NNACLEAVVVTNTIPQERHMQECPK 333
+ A+ L AGA+K+ A +TH +F + R + E +T+++P + +
Sbjct: 146 LIMCAKALKAAGASKISAYVTHAVFPQESWKRFTSRDVPFEKFYITDSLPHAKDIASNSP 205
Query: 334 IQCIDVSMMLAEAV 347
+ + +++E +
Sbjct: 206 FHLLSLCDVISETL 219
>UniRef50_A0CXZ2 Cluster: Chromosome undetermined scaffold_30, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_30,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 340
Score = 52.4 bits (120), Expect = 2e-05
Identities = 26/88 (29%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Query: 245 KANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPA 304
+ E++++ L+ +D I+VDDM DT T+ ++ L E GA +V+A TH +FSG
Sbjct: 167 RMTEISNVSLIIYFQD--CIIVDDMIDTASTLSEVSKVLKEQGAIRVFAFATHALFSGKE 224
Query: 305 ISRINNACLEAVVVTNTIPQERHMQECP 332
+++ L+ ++V +P ++ P
Sbjct: 225 FINLSSPSLDQIIVIIYLPFNYYINIIP 252
>UniRef50_P58860 Cluster: Orotate phosphoribosyltransferase; n=1;
Methanopyrus kandleri|Rep: Orotate
phosphoribosyltransferase - Methanopyrus kandleri
Length = 183
Score = 45.6 bits (103), Expect = 0.002
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 4/84 (4%)
Query: 204 ENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTA 263
E +PD ++ P+ G V+ ++ + + A++ K +K+ +VGDV+ R
Sbjct: 56 EVLPDG--DVLAGPELGAVPLVSVLSVKAGLPMAIVRKRKKEYG--TGERIVGDVRGRKV 111
Query: 264 ILVDDMADTCGTICHAAEKLIEAG 287
+LVDD+A T G++ A E + E G
Sbjct: 112 VLVDDVATTGGSLLEALEAIEEEG 135
>UniRef50_A2XQT7 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 165
Score = 44.8 bits (101), Expect = 0.004
Identities = 22/41 (53%), Positives = 32/41 (78%), Gaps = 1/41 (2%)
Query: 95 VRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAV 135
+RG DV++VQ + +N+NLM+LLIM +AC ASA+ +TAV
Sbjct: 85 LRGYDVFLVQP-TCPVNENLMDLLIMTDACMRASANSITAV 124
>UniRef50_Q2FPQ2 Cluster: Orotate phosphoribosyltransferase; n=4;
Methanomicrobiales|Rep: Orotate
phosphoribosyltransferase - Methanospirillum hungatei
(strain JF-1 / DSM 864)
Length = 172
Score = 44.4 bits (100), Expect = 0.005
Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 6/127 (4%)
Query: 187 IPVDNLFAEPAVLKWIKENIPDWKTSI--VVSPDAGGAKRVTSIADRLNVEFALIHKERK 244
I + PA+LK I + T V GG S++ + + +I KE+K
Sbjct: 33 IDIKKAITSPAILKKIAAEVLTHSTDFDAVAGVAVGGVPLAVSVSLASDKPYVIIRKEQK 92
Query: 245 KANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGA--TKVYAILTHGIFSG 302
+ +AS++ +GDV + +LV+D+ + G+ E+L AGA T V A++ +G
Sbjct: 93 -GHGLASLI-IGDVAGKRILLVEDVTTSGGSAVFGIEQLRSAGAVVTDVIAVVDRNEGAG 150
Query: 303 PAISRIN 309
+ ++
Sbjct: 151 KTLQGLD 157
>UniRef50_Q12V34 Cluster: PyrE-like protein; n=2;
Methanosarcinaceae|Rep: PyrE-like protein -
Methanococcoides burtonii (strain DSM 6242)
Length = 203
Score = 41.9 bits (94), Expect = 0.025
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 4/83 (4%)
Query: 213 IVVSPDAGGAKRVTSIADRLNVEFALIHK---ERKKANEVASMVL-VGDVKDRTAILVDD 268
+V+ G T +A+ L ++FA+ H ++ K N+ DV+ + I+VDD
Sbjct: 92 LVIGIGLSGIPIATMMAEELEIDFAIFHDYDDQKGKTNQRGIFSRNFADVEGKKCIIVDD 151
Query: 269 MADTCGTICHAAEKLIEAGATKV 291
+ + T+ AE+L E GAT +
Sbjct: 152 VVSSGATVTDVAEQLREVGATPI 174
>UniRef50_Q30L82 Cluster: Gp63; n=1; Listeria phage P100|Rep: Gp63 -
Listeria phage P100
Length = 304
Score = 41.5 bits (93), Expect = 0.033
Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 21/154 (13%)
Query: 209 WKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERK----------KANEVASMVLVGDV 258
W ++V PD G R +A + F + R+ + S+ LVG+
Sbjct: 152 WWEPVLVYPDKGAKDRYDKLATDSDYSFRRATENRRVLFGNKVRDFDTGRIKSLELVGEP 211
Query: 259 KDR---TAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEA 315
R TAI+VDD+ GT A + I+ GA++V ++ H G A ++
Sbjct: 212 PTRKGWTAIIVDDLTSYGGTFVKTATEAIKLGASRVVLLVAH--MEGSATKGELFESIDK 269
Query: 316 VVVTNTI-----PQE-RHMQECPKIQCIDVSMML 343
V TN++ P+E + ++ K+ +DV+ ++
Sbjct: 270 VYTTNSMEASYTPEELKEVERYKKLGLLDVTNII 303
>UniRef50_Q9K9W3 Cluster: Orotate phosphoribosyltransferase; n=54;
Bacilli|Rep: Orotate phosphoribosyltransferase -
Bacillus halodurans
Length = 210
Score = 41.5 bits (93), Expect = 0.033
Identities = 33/124 (26%), Positives = 60/124 (48%), Gaps = 13/124 (10%)
Query: 202 IKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERK---KANEVASMVLVGDV 258
I+ + P+ ++V G ++DRL + + K K N++ +
Sbjct: 58 IRSHFPE--VTVVAGTATAGIPHAAWVSDRLQAPMVYVRSKSKGHGKQNQIEGKL---SS 112
Query: 259 KDRTAILVDDMADTCGTICHAAEKLIEAGA--TKVYAILTHGIFSGPAISRINNACLEAV 316
KDR ++++D+ T G++ AA+ L EAGA V AI T+G+ G ++ A L +
Sbjct: 113 KDRV-VIIEDLISTGGSVIQAADALREAGADVLGVVAIFTYGLEKGQ--DQLEAANLPSY 169
Query: 317 VVTN 320
V+T+
Sbjct: 170 VLTD 173
>UniRef50_Q8FRQ5 Cluster: Uracil phosphoribosyltransferase; n=28;
Actinomycetales|Rep: Uracil phosphoribosyltransferase -
Corynebacterium efficiens
Length = 211
Score = 41.1 bits (92), Expect = 0.044
Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 257 DVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAV 316
D+ D+ LVD M T G++ HA L E GAT + AI + + P + + N+ L
Sbjct: 119 DLSDQPVFLVDPMLATGGSLLHAIRLLAERGATDITAICM--VSAQPGVDALKNSGLPCR 176
Query: 317 VVTNTIPQE 325
+VT I E
Sbjct: 177 LVTAAIDPE 185
>UniRef50_O08359 Cluster: Orotate phosphoribosyltransferase; n=4;
Sulfolobaceae|Rep: Orotate phosphoribosyltransferase -
Sulfolobus acidocaldarius
Length = 197
Score = 39.9 bits (89), Expect = 0.10
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
Query: 220 GGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHA 279
GG + IA +LN I E+K +L DV + I+VDD+A T G+I A
Sbjct: 67 GGVPFASFIACKLNKPMGYIRAEKK--GHGTERLLEADVDGKKVIVVDDVATTGGSILKA 124
Query: 280 AEKLIEAGATKVYAIL 295
E++ +AG +A++
Sbjct: 125 VEEVRKAGGKVEHALV 140
>UniRef50_A2BJ25 Cluster: Orotate phosphoribosyltransferase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Orotate
phosphoribosyltransferase - Hyperthermus butylicus
(strain DSM 5456 / JCM 9403)
Length = 201
Score = 39.1 bits (87), Expect = 0.18
Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 198 VLKWIKENIPDWK-TSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVG 256
VL + E + D + +VV G T +A A + +RK+ V+ G
Sbjct: 50 VLGMLAEKLNDVREVDVVVGVATAGIIWATGLALLSEKPLAYVRPKRKEHG--LQRVVEG 107
Query: 257 DVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAIL 295
V+ R ++VDD+A T ++ A E L EAGA V A++
Sbjct: 108 IVEGRRVLVVDDVATTGSSLASAVESLREAGAEPVAAMV 146
>UniRef50_UPI00015BABBC Cluster: phosphoribosyltransferase; n=1;
Ignicoccus hospitalis KIN4/I|Rep:
phosphoribosyltransferase - Ignicoccus hospitalis KIN4/I
Length = 197
Score = 38.7 bits (86), Expect = 0.24
Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 8/92 (8%)
Query: 220 GGAKRVTSIADRLNVEFALIHKER-----KKANEVASMVLVGDVKDRTAILVDDMADTCG 274
GG IAD L +E ++ + KK V ++ L+G+V D +LVDD+ D+ G
Sbjct: 55 GGYVPAHLIADALGLELYVMRIKSYRGIGKKGKPVVTLPLIGNVTDLRILLVDDVCDS-G 113
Query: 275 TICHAAEKLIEAGATKVYAILTHGIFSGPAIS 306
A+K +EA + K +I T +F P S
Sbjct: 114 ETLSVAKKFLEAYSPK--SITTAVLFKKPQCS 143
>UniRef50_A0Y8V6 Cluster: Competence protein ComF, putative; n=1;
marine gamma proteobacterium HTCC2143|Rep: Competence
protein ComF, putative - marine gamma proteobacterium
HTCC2143
Length = 243
Score = 38.3 bits (85), Expect = 0.31
Identities = 16/55 (29%), Positives = 35/55 (63%)
Query: 238 LIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVY 292
++ +++++N + + GDV + +VDD+ T T+ A++ L++AGAT+V+
Sbjct: 181 MLTADQRRSNMKGAFQMCGDVAGKLVAVVDDVMTTGTTVSEASQCLLKAGATEVH 235
>UniRef50_Q314R1 Cluster: ComF family protein; n=1; Desulfovibrio
desulfuricans G20|Rep: ComF family protein -
Desulfovibrio desulfuricans (strain G20)
Length = 251
Score = 37.5 bits (83), Expect = 0.54
Identities = 19/55 (34%), Positives = 31/55 (56%)
Query: 241 KERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAIL 295
KE ++ N + V+ R +LVDD+ T T+ H A+ L AGA +V+A++
Sbjct: 184 KEERRRNLRDAFEADSCVRGRNVLLVDDVMTTGATLEHCAQALYHAGAQQVHAVV 238
>UniRef50_Q26998 Cluster: Uracil phosphoribosyltransferase; n=15;
Eukaryota|Rep: Uracil phosphoribosyltransferase -
Toxoplasma gondii
Length = 244
Score = 37.1 bits (82), Expect = 0.72
Identities = 17/55 (30%), Positives = 29/55 (52%)
Query: 254 LVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRI 308
L D++DR +L+D M T G++C A E L+ G + I + + + I R+
Sbjct: 151 LPADIRDRWVMLLDPMCATAGSVCKAIEVLLRLGVKEERIIFVNILAAPQGIERV 205
>UniRef50_Q4Z9R5 Cluster: ORF031; n=2; unclassified Myoviridae|Rep:
ORF031 - Staphylococcus phage G1
Length = 302
Score = 36.7 bits (81), Expect = 0.95
Identities = 37/174 (21%), Positives = 76/174 (43%), Gaps = 16/174 (9%)
Query: 136 IPCFPYARQDKKDKSRAPI-TAKLVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFA 194
I PY+R D+ ++ + + K + ++ + + H+ + + N FA
Sbjct: 78 IAYLPYSRMDRVEEGHNNMFSLKYITEFINNLNYKSVWVAEPHSPVTEEL----LTNSFA 133
Query: 195 EPAVLKWIKENIPDWKTSI-VVSPDAGGAKRVTSIADRL----NVE-FALIHKERKKANE 248
LK + + I + + +V PD G R +R+ N+E +++++ E+K+ E
Sbjct: 134 IDVTLKLLNQYIEMSEEPVTIVLPDKGAYDRYLFDVERILMESNIESYSIVYGEKKRDFE 193
Query: 249 VASMVLVGDVKDRTA-----ILVDDMADTCGTICHAAEKLIEAGATKVYAILTH 297
+ + +KD+ I++DD+ GT + L + + V ILTH
Sbjct: 194 TGKIKGIKIIKDKNTLYDNCIILDDLTSYGGTFVGCKKALDKLKVSSVSLILTH 247
>UniRef50_O58855 Cluster: Orotate phosphoribosyltransferase; n=3;
Thermococcaceae|Rep: Orotate phosphoribosyltransferase -
Pyrococcus horikoshii
Length = 186
Score = 36.7 bits (81), Expect = 0.95
Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Query: 187 IPVDNLFAEPAVL----KWIKENIPDWKTSI--VVSPDAGGAKRVTSIADRLNVEFALIH 240
I + +L P L K IKE + + + P+ G T+++ N ++
Sbjct: 34 IDIKSLITNPKALRIIAKLIKEKAEELNLNYDKIAGPELGAVPIATALSLETNKPLLIVR 93
Query: 241 KERKKANEVASMVLVGDV-KDRTAILVDDMADTCGTICHAAEKLIEAGATKV 291
K++K+ V+ G+V K +LV+D+ T G++ AA+ L E GA V
Sbjct: 94 KKKKEHG--TGKVIEGNVQKGDKVLLVEDVTTTGGSVIRAAKILREHGADVV 143
>UniRef50_UPI00015BD983 Cluster: UPI00015BD983 related cluster; n=1;
unknown|Rep: UPI00015BD983 UniRef100 entry - unknown
Length = 287
Score = 36.3 bits (80), Expect = 1.3
Identities = 21/61 (34%), Positives = 39/61 (63%), Gaps = 4/61 (6%)
Query: 220 GGAKRVTSIADRLNVEFALIH---KERKKANEVASMVLVGDV-KDRTAILVDDMADTCGT 275
GG K +T++ ++LN++ I+ K K++ +VA MVL+G + KD ++L +M++ G
Sbjct: 63 GGGKDITNMLNKLNIQTEFINGIRKTDKESLDVARMVLIGKLNKDIVSMLNKEMSNMHGA 122
Query: 276 I 276
I
Sbjct: 123 I 123
>UniRef50_A2U7L3 Cluster: Late competence protein; n=1; Bacillus
coagulans 36D1|Rep: Late competence protein - Bacillus
coagulans 36D1
Length = 235
Score = 36.3 bits (80), Expect = 1.3
Identities = 16/37 (43%), Positives = 26/37 (70%)
Query: 258 VKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAI 294
++ R+ +LVDD+ T T+ HAA+ L EAGA K+ ++
Sbjct: 194 IEGRSVLLVDDIYTTGSTVRHAAKVLREAGARKIVSL 230
>UniRef50_A4FCI4 Cluster: Phosphoribosyltransferase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
Phosphoribosyltransferase - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 209
Score = 35.9 bits (79), Expect = 1.7
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 257 DVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAV 316
DV+ RTAI+VDD T T A E GA +V +L + A+ R+ E V
Sbjct: 103 DVRGRTAIVVDDGIRTGSTAHTACRVAHELGAAEV--VLAVPVAPPQALERLEEVTDEQV 160
Query: 317 VVTNTIPQE---RHMQECPKIQCIDVSMMLAEAVR 348
+ P E R + P ++ +VS +L AV+
Sbjct: 161 CLATVGPAEPISRSYRCFPPVRDAEVSRLLRRAVQ 195
>UniRef50_Q4Q3E4 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 782
Score = 35.9 bits (79), Expect = 1.7
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 218 DAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTIC 277
D+ A+RV+ DR + +H+ +++A A M + + +DR +VD TC +C
Sbjct: 573 DSATAQRVSESEDRKRAASSALHETKQQAQASAEMADLAEARDRLLCVVD---HTCQQVC 629
Query: 278 HAAEKL 283
+ L
Sbjct: 630 DVGDSL 635
>UniRef50_Q0S3S3 Cluster: Possible phosphoribosyltransferase; n=11;
Bacteria|Rep: Possible phosphoribosyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 209
Score = 35.5 bits (78), Expect = 2.2
Identities = 44/177 (24%), Positives = 76/177 (42%), Gaps = 15/177 (8%)
Query: 150 SRAPITAKLVANILSVSGADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIKENIPDW 209
SRA +L A + + G D ++ + L + F++ L A V+ K +P W
Sbjct: 5 SRADAGRRLAAALEHLRGTD-LVVLGLPRGGVPVAFEVAAA-LSAPLDVVLVRKLGVP-W 61
Query: 210 KTSIVVSPDAGGAKRVTS-----IADRLNVEFALIHKERKKANEVASMVLVG-----DVK 259
+ + + G RV + IA A++ + ++ E + VL G +K
Sbjct: 62 QPELAMGAIGEGESRVINDDVLRIARISKTALAMVEAKERRELERRARVLRGGKPRASLK 121
Query: 260 DRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACLEAV 316
RTA+LVDD T T A + + + GA +V I+ + + A+ R+ E V
Sbjct: 122 GRTAVLVDDGMATGATAAVACQSVKKLGAARV--IVAVPVAAPEAVGRLRVTADEVV 176
>UniRef50_Q5KV55 Cluster: Late competence protein; n=2;
Geobacillus|Rep: Late competence protein - Geobacillus
kaustophilus
Length = 230
Score = 35.1 bits (77), Expect = 2.9
Identities = 19/54 (35%), Positives = 31/54 (57%)
Query: 241 KERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAI 294
+ER K + + + + +L+DD+ T TI HAA L+EAGA +V+A+
Sbjct: 172 RERLKTDNPFFLADHPPLDGKRIVLIDDIYTTGITIRHAARVLLEAGAAEVWAL 225
>UniRef50_Q1VXI5 Cluster: Hypoxanthine-guanine
phosphoribosyltransferase; n=4; Flavobacteriales|Rep:
Hypoxanthine-guanine phosphoribosyltransferase -
Psychroflexus torquis ATCC 700755
Length = 179
Score = 35.1 bits (77), Expect = 2.9
Identities = 15/48 (31%), Positives = 30/48 (62%)
Query: 240 HKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAG 287
+K + EV++++ G++KDR I+++D+ DT T+ H +L + G
Sbjct: 72 YKGTSSSGEVSTLLGAGNLKDRDVIVIEDIVDTGLTLEHIVSQLKKEG 119
>UniRef50_Q5FFA1 Cluster: Similar to competence protein F; n=2;
Ehrlichia ruminantium|Rep: Similar to competence protein
F - Ehrlichia ruminantium (strain Gardel)
Length = 230
Score = 34.7 bits (76), Expect = 3.8
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 3/62 (4%)
Query: 235 EFALIHKERKKANEVASMVLVGDVK--DRTAILVDDMADTCGTICHAAEKLIEAGATKVY 292
+++L K RK+ N + S ++ K ++T +LVDD+ T T+ ++KLIE+GA ++
Sbjct: 164 QYSLSSKMRKE-NIMQSFIIKNQHKIYNKTILLVDDVVTTGITVRTCSQKLIESGAKEIR 222
Query: 293 AI 294
I
Sbjct: 223 VI 224
>UniRef50_Q3IJQ7 Cluster: Putative uncharacterized protein; n=2;
Alteromonadales|Rep: Putative uncharacterized protein -
Pseudoalteromonas haloplanktis (strain TAC 125)
Length = 225
Score = 34.7 bits (76), Expect = 3.8
Identities = 17/56 (30%), Positives = 30/56 (53%)
Query: 241 KERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILT 296
K ++ N + + D+ +T +VDD+ T T+ A + L +AGA +V+A T
Sbjct: 165 KAKRVKNLKDAFICTADMSGKTVAIVDDIMTTGATLNAATQALKQAGAKQVWAFTT 220
>UniRef50_A1TIR0 Cluster: Rhs element Vgr protein; n=15; cellular
organisms|Rep: Rhs element Vgr protein - Acidovorax
avenae subsp. citrulli (strain AAC00-1)
Length = 907
Score = 34.7 bits (76), Expect = 3.8
Identities = 16/58 (27%), Positives = 31/58 (53%)
Query: 37 KLDHVLPLTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGES 94
+L L + TR + ++F + P + Q+++ R G L +T+ + + CV+ GES
Sbjct: 89 RLQPWLWVATRRQDFRIFQFKTVPQIVQEVLGRYGYPLQLKLTRAYRAWDYCVQYGES 146
>UniRef50_Q8N427 Cluster: Thioredoxin domain-containing protein 3;
n=18; Eutheria|Rep: Thioredoxin domain-containing
protein 3 - Homo sapiens (Human)
Length = 588
Score = 34.7 bits (76), Expect = 3.8
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 30 TLEDVVNKLDHVLPLTTRMPNIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCV 89
+LE ++ H PL + + IK + S + KIV G DL + V K F E
Sbjct: 436 SLETAEREIQHFFPLQSTLGLIKPHATSEQREQILKIVKEAGFDLTQ-VKKMFLTPEQIE 494
Query: 90 EIGESVRGEDVY 101
+I V G+D Y
Sbjct: 495 KIYPKVTGKDFY 506
>UniRef50_Q1AVJ4 Cluster: Phosphoribosyltransferase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
Phosphoribosyltransferase - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 227
Score = 34.3 bits (75), Expect = 5.1
Identities = 18/39 (46%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 256 GDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAI 294
G V+ R +LVDD+ T T+ A L+EAGA+ VYA+
Sbjct: 184 GRVRGRV-LLVDDVLTTGATMSECARVLLEAGASGVYAV 221
>UniRef50_Q04H27 Cluster: Orotate phosphoribosyltransferase; n=1;
Oenococcus oeni PSU-1|Rep: Orotate
phosphoribosyltransferase - Oenococcus oeni (strain
BAA-331 / PSU-1)
Length = 211
Score = 34.3 bits (75), Expect = 5.1
Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 202 IKENIPDWKTSIVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLV--GDVK 259
I N PD I+ G ++DR+N + R KA + S + V
Sbjct: 62 IISNYPD--VEIIGGVATAGIPHAAFVSDRMNKPMIYV---RSKARDHGSKHQIEGAQVD 116
Query: 260 DRTAILVDDMADTCGTICHAAEKLIEAGA 288
++ +L+DD+ T G++ AA + EAGA
Sbjct: 117 NKKLVLIDDLISTGGSVLAAARTVQEAGA 145
>UniRef50_A0IM27 Cluster: Rhs element Vgr protein; n=4;
Enterobacteriaceae|Rep: Rhs element Vgr protein -
Serratia proteamaculans 568
Length = 769
Score = 34.3 bits (75), Expect = 5.1
Identities = 13/45 (28%), Positives = 24/45 (53%)
Query: 50 NIKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGES 94
N ++F PD+ + ++D G+ + +T + N E CV+ ES
Sbjct: 108 NQRIFQNQRVPDIIKTVLDEYGVQMENQLTGSYRNWEYCVQYQES 152
>UniRef50_A0DXS4 Cluster: Chromosome undetermined scaffold_69, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_69,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 476
Score = 34.3 bits (75), Expect = 5.1
Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 12/99 (12%)
Query: 51 IKVFSGSSHPDLAQKIVDRLGIDLGKVVTKKFSNMETCVEIGESVRGEDVYIVQSGSGEI 110
I VF+ +S+PD A KI+D L V + F + C++I + +D+ I +
Sbjct: 340 IMVFT-ASNPDYANKIIDYLDPQHKLVSYRLF--RDDCIQISNNCHIKDLRI-------L 389
Query: 111 NDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDK 149
N N+ +++++ N+ + A +V IP PY DK DK
Sbjct: 390 NRNMKDIVLVDNSA-YSFAFQVENGIPIIPYL-DDKNDK 426
>UniRef50_Q41CE1 Cluster: Late competence protein; n=1;
Exiguobacterium sibiricum 255-15|Rep: Late competence
protein - Exiguobacterium sibiricum 255-15
Length = 215
Score = 33.9 bits (74), Expect = 6.7
Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Query: 224 RVTSIADRLNVEFALIHKERKKANEVASMV-LVGDVKDRTAILVDDMADTCGTICHAAEK 282
R+ + +R N A H+ R + E + ++ V +T +LVDD+ T T+ AA +
Sbjct: 139 RIRLVLERTN-GVAFSHQTRHERLERDNPYHVMQPVTGKTILLVDDVYTTGTTLHQAASR 197
Query: 283 LIEAGATKVYAI 294
L EAGA ++ A+
Sbjct: 198 LYEAGAKEISAV 209
>UniRef50_A7TEN3 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 633
Score = 33.9 bits (74), Expect = 6.7
Identities = 22/70 (31%), Positives = 33/70 (47%)
Query: 85 METCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQ 144
M T V++ ES G++VY + D + E+ + IAS+S +T V RQ
Sbjct: 392 MSTAVKVEESKNGKNVYNTNDLNSIRGDQVNEISNSSSISSIASSSPLTHVYRSMVQKRQ 451
Query: 145 DKKDKSRAPI 154
+K S PI
Sbjct: 452 NKIPSSSTPI 461
>UniRef50_Q97PP4 Cluster: Phosphoglucosamine mutase; n=67;
Bacteria|Rep: Phosphoglucosamine mutase - Streptococcus
pneumoniae
Length = 450
Score = 33.9 bits (74), Expect = 6.7
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 5/117 (4%)
Query: 10 DSVASPLATTSGLVSMKSTITLEDVVNKLDHVLPLTTRMPNIKVFSGSSHPDLAQKIVDR 69
D + L T +G S + D+ +L V+ T NI + GS+HP+ Q++V
Sbjct: 172 DGMKVALDTANGAASTSARQIFADLGAQLT-VIGETPDGLNINLNVGSTHPEALQEVVKE 230
Query: 70 LGIDLGKVVTKKFSNMETCVEIGESVRGEDV-YIV---QSGSGEINDNLMELLIMIN 122
G +G + E G+ V G+ + YI+ S G++ N + +M N
Sbjct: 231 SGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLAQNTIVTTVMSN 287
>UniRef50_Q39CP3 Cluster: Phosphoribosyltransferase; n=30;
Burkholderia|Rep: Phosphoribosyltransferase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 263
Score = 33.5 bits (73), Expect = 8.9
Identities = 17/53 (32%), Positives = 28/53 (52%)
Query: 239 IHKERKKANEVASMVLVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKV 291
+ + ++ N +A+ + G V R LVDD+ + T+ AA L AGA +V
Sbjct: 200 LDRHARRDNVMAAFAVAGGVAGRHVALVDDVMTSGATLAAAAHALKAAGAARV 252
>UniRef50_Q7XY42 Cluster: Oxidoreductase; n=1; Griffithsia
japonica|Rep: Oxidoreductase - Griffithsia japonica (Red
alga)
Length = 157
Score = 33.5 bits (73), Expect = 8.9
Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Query: 199 LKW-IKENIPDW--KTSIVVSPDAG-GAKRVTSIADR-LNVEFALIHKERKKANEVASMV 253
+KW +++N+PD KT ++ ++G G + R + A + ++ A V+
Sbjct: 5 MKWSVEDNVPDMTGKTVLITGSNSGLGYHCADQLLSRGATIVLACRNADKMGAAAVSLQA 64
Query: 254 LVGDVKDRTAILVDDMADTCGTICHAAEKLIEAGATKVYAILTHGIFSGPAISRINNACL 313
G R L D++D ++ A L+E G + +Y ++ + +G + L
Sbjct: 65 AHGTPASRILQLQLDVSDLV-SVRAAPAALLELGVSALYGLVLNAGVNGRDVVTFTTDGL 123
Query: 314 EAVVVTNTI 322
E V VTN +
Sbjct: 124 ERVFVTNIL 132
>UniRef50_A3DM49 Cluster: Orotate phosphoribosyltransferase; n=1;
Staphylothermus marinus F1|Rep: Orotate
phosphoribosyltransferase - Staphylothermus marinus
(strain ATCC 43588 / DSM 3639 / F1)
Length = 203
Score = 33.5 bits (73), Expect = 8.9
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 213 IVVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDRTAILVDDMADT 272
IVV ++ G + IA + + + K+ K+ ++ G V DR ++VDD+A T
Sbjct: 67 IVVGIESAGIIHASFIACKTHKPVGYVRKKPKQHG--TKRLVEGIVADRNVLVVDDVATT 124
Query: 273 CGTICHAAEKLIEAG 287
G++ HA + G
Sbjct: 125 GGSLEHAVNAVRSMG 139
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.132 0.375
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 363,087,553
Number of Sequences: 1657284
Number of extensions: 13710321
Number of successful extensions: 36411
Number of sequences better than 10.0: 189
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 35926
Number of HSP's gapped (non-prelim): 226
length of query: 365
length of database: 575,637,011
effective HSP length: 102
effective length of query: 263
effective length of database: 406,594,043
effective search space: 106934233309
effective search space used: 106934233309
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 73 (33.5 bits)
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