Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001383-TA|BGIBMGA001383-PA|IPR005886|UDP-glucose
4-epimerase, IPR001509|NAD-dependent epimerase/dehydratase
(356 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q14376 Cluster: UDP-glucose 4-epimerase; n=150; cellula... 410 e-113
UniRef50_P18645 Cluster: UDP-glucose 4-epimerase; n=353; cellula... 388 e-107
UniRef50_O54385 Cluster: UDP-glucose epimerase; n=11; cellular o... 366 e-100
UniRef50_Q9T0A7 Cluster: Probable UDP-glucose 4-epimerase At4g23... 356 6e-97
UniRef50_Q42605 Cluster: UDP-glucose 4-epimerase; n=20; Viridipl... 343 6e-93
UniRef50_A5M424 Cluster: UDP-glucose 4-epimerase; n=1; Streptoco... 341 2e-92
UniRef50_Q8H931 Cluster: Putative UDP-glucose 4-epimerase; n=5; ... 334 2e-90
UniRef50_P04397 Cluster: Bifunctional protein GAL10 [Includes: U... 322 1e-86
UniRef50_Q7VAY9 Cluster: UDP-glucose 4-epimerase; n=2; Prochloro... 320 3e-86
UniRef50_UPI0000DAE763 Cluster: hypothetical protein Rgryl_01001... 314 2e-84
UniRef50_A5GHV3 Cluster: UDP-glucose-4-epimerase; n=11; Cyanobac... 312 7e-84
UniRef50_A0VUL2 Cluster: UDP-glucose 4-epimerase; n=2; Rhodobact... 307 3e-82
UniRef50_Q0IDK5 Cluster: UDP-glucose 4-epimerase; n=3; Cyanobact... 295 9e-79
UniRef50_Q7MX67 Cluster: UDP-glucose 4-epimerase; n=12; Bacteroi... 292 8e-78
UniRef50_A1ZWK4 Cluster: UDP-glucose 4-epimerase; n=16; Bacteroi... 292 8e-78
UniRef50_A4QBQ0 Cluster: Putative uncharacterized protein; n=1; ... 278 2e-73
UniRef50_Q5QPP4 Cluster: UDP-galactose-4-epimerase; n=6; cellula... 277 4e-73
UniRef50_Q5K809 Cluster: Galactose metabolism-related protein, p... 274 3e-72
UniRef50_Q1MP11 Cluster: Nucleoside-diphosphate-sugar epimerases... 266 8e-70
UniRef50_A3PE72 Cluster: UDP-glucose 4-epimerase; n=2; Prochloro... 264 2e-69
UniRef50_Q5QXD9 Cluster: UDP-glucose 4-epimerase; n=1; Idiomarin... 260 4e-68
UniRef50_UPI00006CC433 Cluster: UDP-glucose 4-epimerase family p... 260 5e-68
UniRef50_Q8R8R8 Cluster: UDP-glucose 4-epimerase; n=15; Bacteria... 253 6e-66
UniRef50_A2BSF0 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro... 251 2e-65
UniRef50_Q9KDV3 Cluster: UDP-glucose 4-epimerase; n=124; cellula... 249 7e-65
UniRef50_A6RJ24 Cluster: Putative uncharacterized protein; n=2; ... 247 4e-64
UniRef50_Q2UPV8 Cluster: UDP-glucose 4-epimerase; n=7; Trichocom... 241 1e-62
UniRef50_A2R0Z8 Cluster: Catalytic activity: UDPglucose = UDPgal... 229 1e-58
UniRef50_Q4WQU9 Cluster: UDP-glucose 4-epimerase; n=3; Pezizomyc... 225 1e-57
UniRef50_A0CJT6 Cluster: Chromosome undetermined scaffold_2, who... 224 3e-57
UniRef50_Q1YMT2 Cluster: UDP-glucose 4-epimerase; n=3; Alphaprot... 218 2e-55
UniRef50_A6C8E4 Cluster: UDP-glucose 4-epimerase; n=1; Planctomy... 218 2e-55
UniRef50_Q9SGX0 Cluster: F1N19.2; n=1; Arabidopsis thaliana|Rep:... 217 4e-55
UniRef50_P96995 Cluster: UDP-glucose 4-epimerase; n=51; Bacteria... 217 4e-55
UniRef50_A6LLZ0 Cluster: UDP-glucose 4-epimerase; n=2; Bacteria|... 217 5e-55
UniRef50_Q9ABX8 Cluster: UDP-glucose 4-epimerase; n=1; Caulobact... 215 1e-54
UniRef50_Q0U254 Cluster: Putative uncharacterized protein; n=1; ... 215 1e-54
UniRef50_Q9SA77 Cluster: UDP-arabinose 4-epimerase 1; n=31; Viri... 213 4e-54
UniRef50_Q5KUQ5 Cluster: UDP-glucose 4-epimerase; n=5; Bacteria|... 213 6e-54
UniRef50_Q8YN57 Cluster: UDP-glucose 4-epimerase; n=43; Bacteria... 213 8e-54
UniRef50_A0Z893 Cluster: UDP-glucose 4-epimerase; n=1; marine ga... 211 2e-53
UniRef50_Q8RGC6 Cluster: UDP-glucose 4-epimerase; n=2; Fusobacte... 204 3e-51
UniRef50_Q5FQW6 Cluster: UDP-glucose 4-epimerase; n=3; Bacteria|... 201 3e-50
UniRef50_A5AK58 Cluster: Putative uncharacterized protein; n=1; ... 198 2e-49
UniRef50_UPI0000383ECD Cluster: COG1087: UDP-glucose 4-epimerase... 194 2e-48
UniRef50_Q59083 Cluster: UDP-glucose 4-epimerase; n=14; Bacteria... 192 9e-48
UniRef50_A3ERM8 Cluster: UDP-glucose 4-epimerase; n=1; Leptospir... 190 5e-47
UniRef50_Q6KI97 Cluster: Udp-glucose 4-epimerase; n=1; Mycoplasm... 187 3e-46
UniRef50_Q6MS04 Cluster: UDP-glucose 4-epimerase; n=3; Mycoplasm... 185 1e-45
UniRef50_Q1QJ29 Cluster: UDP-glucose 4-epimerase; n=1; Nitrobact... 185 2e-45
UniRef50_A0LVI8 Cluster: UDP-glucose 4-epimerase; n=6; Actinomyc... 184 3e-45
UniRef50_UPI000023E28B Cluster: hypothetical protein FG07983.1; ... 183 7e-45
UniRef50_Q604T5 Cluster: UDP-glucose 4-epimerase; n=26; Proteoba... 182 1e-44
UniRef50_A3PE63 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro... 182 1e-44
UniRef50_Q8KGE4 Cluster: UDP-glucose 4-epimerase; n=14; Bacteria... 179 9e-44
UniRef50_Q65D61 Cluster: Putative uncharacterized protein; n=1; ... 179 9e-44
UniRef50_Q1GKR7 Cluster: UDP-glucose 4-epimerase; n=17; Bacteria... 178 2e-43
UniRef50_Q011T8 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 177 4e-43
UniRef50_Q6FB43 Cluster: Putative UDP-galactose 4-epimerase; n=2... 175 1e-42
UniRef50_Q8DGV6 Cluster: UDP-glucose 4-epimerase; n=1; Synechoco... 175 2e-42
UniRef50_A1SPC3 Cluster: UDP-glucose 4-epimerase precursor; n=2;... 175 2e-42
UniRef50_Q9RSC3 Cluster: UDP-glucose 4-epimerase; n=1; Deinococc... 173 4e-42
UniRef50_Q8G3T3 Cluster: UDP-glucose 4-epimerase; n=5; Actinobac... 173 6e-42
UniRef50_A3Q712 Cluster: UDP-glucose 4-epimerase; n=6; Actinobac... 172 1e-41
UniRef50_UPI00015BC7D2 Cluster: UPI00015BC7D2 related cluster; n... 169 1e-40
UniRef50_Q7VJ63 Cluster: UDP-glucose 4-epimerase; n=30; Epsilonp... 168 2e-40
UniRef50_Q7CS52 Cluster: AGR_L_3011p; n=3; Alphaproteobacteria|R... 167 3e-40
UniRef50_A4AI37 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 167 5e-40
UniRef50_Q0BRM8 Cluster: UDP-glucose 4-epimerase; n=2; Rhodospir... 166 7e-40
UniRef50_A0L5P6 Cluster: UDP-glucose 4-epimerase; n=4; Bacteria|... 164 3e-39
UniRef50_Q07GF0 Cluster: UDP-glucose 4-epimerase; n=1; Roseobact... 163 6e-39
UniRef50_Q9L047 Cluster: UDP-glucose 4-epimerase; n=7; Actinomyc... 160 4e-38
UniRef50_P72903 Cluster: UDP-glucose-4-epimerase; n=20; Bacteria... 159 8e-38
UniRef50_A2BZ28 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro... 159 8e-38
UniRef50_A0LJ03 Cluster: UDP-glucose 4-epimerase; n=1; Syntropho... 159 8e-38
UniRef50_Q4Q3V7 Cluster: Udp-glc 4'-epimerase, putative; n=7; Tr... 159 1e-37
UniRef50_A6PV21 Cluster: UDP-glucose 4-epimerase; n=1; Victivall... 154 4e-36
UniRef50_A3VS38 Cluster: UDP-glucose 4-epimerase; n=2; Alphaprot... 154 4e-36
UniRef50_Q0C2X5 Cluster: UDP-glucose 4-epimerase; n=1; Hyphomona... 149 8e-35
UniRef50_Q97NY4 Cluster: NAD-dependent epimerase/dehydratase fam... 131 2e-29
UniRef50_A6QU99 Cluster: UDP-glucose 4-epimerase; n=1; Ajellomyc... 129 9e-29
UniRef50_P47364 Cluster: UDP-glucose 4-epimerase; n=4; Mycoplasm... 129 9e-29
UniRef50_Q8TXF0 Cluster: Nucleoside-diphosphate-sugar epimerase;... 128 2e-28
UniRef50_Q57664 Cluster: Putative UDP-glucose 4-epimerase; n=3; ... 125 2e-27
UniRef50_Q5SKQ2 Cluster: UDP-glucose 4-epimerase; n=4; Thermus|R... 117 4e-25
UniRef50_A7CY79 Cluster: NAD-dependent epimerase/dehydratase; n=... 114 3e-24
UniRef50_A1HMB7 Cluster: NAD-dependent epimerase/dehydratase; n=... 112 1e-23
UniRef50_Q9WYX9 Cluster: UDP-glucose 4-epimerase, putative; n=5;... 111 2e-23
UniRef50_Q2FKD1 Cluster: NAD-dependent epimerase/dehydratase fam... 111 4e-23
UniRef50_A4WHT4 Cluster: NAD-dependent epimerase/dehydratase; n=... 110 6e-23
UniRef50_A3ZYG1 Cluster: Nucleotide sugar epimerase; n=1; Blasto... 109 1e-22
UniRef50_A1RW61 Cluster: NAD-dependent epimerase/dehydratase; n=... 108 2e-22
UniRef50_Q67KU6 Cluster: UDP-glucose 4-epimerase; n=1; Symbiobac... 107 4e-22
UniRef50_A5GEM5 Cluster: NAD-dependent epimerase/dehydratase; n=... 107 4e-22
UniRef50_A0RWB8 Cluster: Nucleoside-diphosphate-sugar epimerase;... 107 6e-22
UniRef50_Q9K6S7 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus ... 106 8e-22
UniRef50_O67354 Cluster: Nucleotide sugar epimerase; n=4; Bacter... 106 8e-22
UniRef50_Q1V1Y0 Cluster: UDPglucose 4-epimerase; n=2; Candidatus... 106 1e-21
UniRef50_A0B5G2 Cluster: NAD-dependent epimerase/dehydratase; n=... 106 1e-21
UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5; Halobacte... 104 4e-21
UniRef50_Q8U032 Cluster: NDP-sugar dehydratase or epimerase; n=5... 103 7e-21
UniRef50_A7DQX9 Cluster: NAD-dependent epimerase/dehydratase; n=... 103 7e-21
UniRef50_Q1K169 Cluster: NAD-dependent epimerase/dehydratase; n=... 103 9e-21
UniRef50_Q11WU7 Cluster: UDP-galactose-4-epimerase; n=1; Cytopha... 102 1e-20
UniRef50_Q8PXQ4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 102 1e-20
UniRef50_A6T0C0 Cluster: UDP-glucose 4-epimerase; n=1; Janthinob... 102 2e-20
UniRef50_Q832Q5 Cluster: NAD-dependent epimerase/dehydratase fam... 101 3e-20
UniRef50_Q5V6W4 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcul... 101 3e-20
UniRef50_A6BZU3 Cluster: Putative uncharacterized protein; n=1; ... 100 5e-20
UniRef50_A5UZ84 Cluster: NAD-dependent epimerase/dehydratase; n=... 100 5e-20
UniRef50_Q0YI68 Cluster: NAD-dependent epimerase/dehydratase:Sho... 100 7e-20
UniRef50_A3HAA1 Cluster: NAD-dependent epimerase/dehydratase; n=... 100 1e-19
UniRef50_Q58455 Cluster: Uncharacterized protein MJ1055; n=4; ce... 100 1e-19
UniRef50_Q9K7I2 Cluster: UDP-glucose 4-epimerase; n=17; cellular... 99 2e-19
UniRef50_Q3E561 Cluster: NAD-dependent epimerase/dehydratase:Sho... 98 3e-19
UniRef50_A3ERU6 Cluster: Nucleoside-diphosphate-sugar epimerase;... 98 3e-19
UniRef50_A2SRX5 Cluster: NAD-dependent epimerase/dehydratase; n=... 98 4e-19
UniRef50_Q1Q482 Cluster: Similar to dTDP-glucose 4,6-dehydratase... 97 6e-19
UniRef50_A6GLY7 Cluster: Putative uncharacterized protein; n=1; ... 97 6e-19
UniRef50_Q65E95 Cluster: Putative uncharacterized protein; n=1; ... 97 8e-19
UniRef50_Q2JEQ1 Cluster: NAD-dependent epimerase/dehydratase; n=... 97 8e-19
UniRef50_Q2S4X1 Cluster: UDP-glucuronate 5'-epimerase; n=3; Bact... 95 3e-18
UniRef50_Q7D561 Cluster: NAD-dependent epimerase/dehydratase fam... 95 3e-18
UniRef50_Q2FN70 Cluster: NAD-dependent epimerase/dehydratase pre... 95 3e-18
UniRef50_Q8THP9 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Meth... 94 4e-18
UniRef50_Q5KWG9 Cluster: Nucleotide sugar epimerase; n=1; Geobac... 93 8e-18
UniRef50_Q7P6D7 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 93 1e-17
UniRef50_Q2MFK2 Cluster: Putative apramycin biosynthetic oxidore... 92 2e-17
UniRef50_A4F9Y4 Cluster: UDP-glucose 4-epimerase; n=1; Saccharop... 92 2e-17
UniRef50_Q6MF46 Cluster: Probable UDP-glucuronat epimerase; n=2;... 92 2e-17
UniRef50_Q70PA0 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17
UniRef50_A7HBK8 Cluster: NAD-dependent epimerase/dehydratase; n=... 92 2e-17
UniRef50_A0A003 Cluster: MoeE5; n=1; Streptomyces ghanaensis|Rep... 91 4e-17
UniRef50_A4CBV8 Cluster: NAD dependent epimerase/dehydratase fam... 91 5e-17
UniRef50_Q1AWM7 Cluster: NAD-dependent epimerase/dehydratase pre... 90 7e-17
UniRef50_A5GIA6 Cluster: NAD dependent epimerase/dehydratase; n=... 90 7e-17
UniRef50_Q8KWC8 Cluster: RB114; n=5; Proteobacteria|Rep: RB114 -... 90 9e-17
UniRef50_A1BC39 Cluster: NAD-dependent epimerase/dehydratase; n=... 90 9e-17
UniRef50_Q01U23 Cluster: NAD-dependent epimerase/dehydratase; n=... 89 1e-16
UniRef50_Q93KX6 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 89 2e-16
UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=... 88 3e-16
UniRef50_Q93N66 Cluster: Dehydratase-like protein; n=14; cellula... 88 4e-16
UniRef50_Q1WTH1 Cluster: UDP-glucose 4-epimerase; n=1; Lactobaci... 87 5e-16
UniRef50_Q2NIA3 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 87 5e-16
UniRef50_Q84CM4 Cluster: Nucleotide sugar epimerase; n=4; Proteo... 87 7e-16
UniRef50_O95455 Cluster: dTDP-D-glucose 4,6-dehydratase; n=24; E... 87 9e-16
UniRef50_A4MIF2 Cluster: NAD-dependent epimerase/dehydratase; n=... 86 1e-15
UniRef50_A4FLF3 Cluster: NAD-dependent epimerase/dehydratase; n=... 86 1e-15
UniRef50_A1FN39 Cluster: NAD-dependent epimerase/dehydratase; n=... 86 1e-15
UniRef50_A0UVI4 Cluster: NAD-dependent epimerase/dehydratase; n=... 86 1e-15
UniRef50_Q12UG3 Cluster: NAD-dependent epimerase/dehydratase; n=... 86 1e-15
UniRef50_Q1AWT4 Cluster: NAD-dependent epimerase/dehydratase; n=... 86 2e-15
UniRef50_A1VG42 Cluster: NAD-dependent epimerase/dehydratase; n=... 85 2e-15
UniRef50_Q9HSU9 Cluster: GDP-D-mannose dehydratase; n=2; Halobac... 85 2e-15
UniRef50_A5UK04 Cluster: UDP-glucose 4-epimerase; n=2; Euryarcha... 85 2e-15
UniRef50_Q2RKH0 Cluster: NAD-dependent epimerase/dehydratase; n=... 85 3e-15
UniRef50_Q4HQ86 Cluster: UDP-glucose 4-epimerase, putative; n=2;... 85 3e-15
UniRef50_Q54WS6 Cluster: Putative dTDP-D-glucose 4,6-dehydratase... 85 3e-15
UniRef50_P39630 Cluster: Spore coat polysaccharide biosynthesis ... 85 3e-15
UniRef50_Q88XK0 Cluster: UDP-glucose 4-epimerase; n=2; Lactobaci... 84 6e-15
UniRef50_Q83DA9 Cluster: NAD dependent epimerase/dehydratase fam... 83 8e-15
UniRef50_Q1IM02 Cluster: NAD-dependent epimerase/dehydratase; n=... 83 8e-15
UniRef50_Q9RWF7 Cluster: UDP-glucose 4-epimerase, putative; n=63... 83 1e-14
UniRef50_A0FWU5 Cluster: NAD-dependent epimerase/dehydratase; n=... 83 1e-14
UniRef50_A7D7X9 Cluster: NAD-dependent epimerase/dehydratase; n=... 83 1e-14
UniRef50_A6PTX1 Cluster: NAD-dependent epimerase/dehydratase; n=... 81 3e-14
UniRef50_A6GG02 Cluster: Putative uncharacterized protein; n=1; ... 81 3e-14
UniRef50_A0K2B4 Cluster: NAD-dependent epimerase/dehydratase; n=... 81 3e-14
UniRef50_A2GEF2 Cluster: NAD dependent epimerase/dehydratase fam... 81 3e-14
UniRef50_Q97CP3 Cluster: NDP-sugar epimerase; n=4; Thermoplasmat... 81 3e-14
UniRef50_Q12VP0 Cluster: NAD-dependent epimerase/dehydratase; n=... 81 3e-14
UniRef50_A3PV39 Cluster: NAD-dependent epimerase/dehydratase pre... 81 4e-14
UniRef50_Q1IKI6 Cluster: NAD-dependent epimerase/dehydratase; n=... 81 6e-14
UniRef50_Q9UXJ4 Cluster: DTDP-glucose 4,6-dehydratase; n=2; Sulf... 80 1e-13
UniRef50_A1Y020 Cluster: UDP-glucose 4-epimerase; n=1; Spironucl... 79 1e-13
UniRef50_UPI0001597DB3 Cluster: SpsJ; n=1; Bacillus amyloliquefa... 79 2e-13
UniRef50_Q868I5 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 79 2e-13
UniRef50_Q3JAZ5 Cluster: NAD-dependent epimerase/dehydratase; n=... 79 2e-13
UniRef50_Q41C61 Cluster: NAD-dependent epimerase/dehydratase pre... 79 2e-13
UniRef50_Q1VGF9 Cluster: Putative uncharacterized protein; n=1; ... 79 2e-13
UniRef50_A7HFB5 Cluster: NAD-dependent epimerase/dehydratase; n=... 79 2e-13
UniRef50_A6CLM3 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus ... 79 2e-13
UniRef50_A0LKC0 Cluster: NAD-dependent epimerase/dehydratase; n=... 78 3e-13
UniRef50_O26480 Cluster: UDP-glucose 4-epimerase homolog; n=3; c... 78 3e-13
UniRef50_A6GE58 Cluster: NAD-dependent epimerase/dehydratase fam... 78 4e-13
UniRef50_A5WE41 Cluster: NAD-dependent epimerase/dehydratase; n=... 77 5e-13
UniRef50_Q0W7F9 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 77 5e-13
UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellu... 77 7e-13
UniRef50_Q2RPP2 Cluster: NAD-dependent epimerase/dehydratase; n=... 77 7e-13
UniRef50_A6GMF7 Cluster: Nucleotide sugar epimerase; n=1; Limnob... 77 7e-13
UniRef50_A4VWA8 Cluster: UDP-glucose 4-epimerase; n=1; Streptoco... 77 7e-13
UniRef50_Q4AGU6 Cluster: NAD-dependent epimerase/dehydratase; n=... 77 9e-13
UniRef50_A1IA72 Cluster: Putative UDP-glucose-4-epimerase precur... 77 9e-13
UniRef50_Q8YRD9 Cluster: Nucleotide sugar epimerase; n=6; Cyanob... 76 2e-12
UniRef50_Q2WB63 Cluster: Nucleoside-diphosphate-sugar epimerase;... 76 2e-12
UniRef50_A7HIS5 Cluster: dTDP-glucose 4,6-dehydratase; n=5; cell... 76 2e-12
UniRef50_UPI00015BAE89 Cluster: NAD-dependent epimerase/dehydrat... 75 2e-12
UniRef50_Q5L1Q6 Cluster: NDP-sugar epimerase; n=6; Bacillaceae|R... 75 2e-12
UniRef50_Q07KU6 Cluster: NAD-dependent epimerase/dehydratase pre... 75 3e-12
UniRef50_Q9RZB3 Cluster: Thymidine diphosphoglucose 4,6-dehydrat... 74 7e-12
UniRef50_A5C3L4 Cluster: Putative uncharacterized protein; n=1; ... 74 7e-12
UniRef50_Q7V972 Cluster: Possible UDP-glucose-4-epimerase; n=1; ... 73 9e-12
UniRef50_A3H793 Cluster: NAD-dependent epimerase/dehydratase; n=... 73 9e-12
UniRef50_Q8ZW82 Cluster: UDP-glucose 4-epimerase; n=6; Thermopro... 73 1e-11
UniRef50_Q9SYM5 Cluster: Probable rhamnose biosynthetic enzyme 1... 73 1e-11
UniRef50_Q5FRS4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 73 2e-11
UniRef50_Q2RMP3 Cluster: NAD-dependent epimerase/dehydratase; n=... 73 2e-11
UniRef50_Q3ESA4 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Firm... 73 2e-11
UniRef50_Q20YR4 Cluster: NAD-dependent epimerase/dehydratase; n=... 73 2e-11
UniRef50_A1CX38 Cluster: Dtdp-glucose 4,6-dehydratase; n=6; Pezi... 72 2e-11
UniRef50_Q7UWT1 Cluster: Udp-glucose 4-epimerase; n=3; Bacteria|... 72 3e-11
UniRef50_Q319Q1 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro... 72 3e-11
UniRef50_A4BEM6 Cluster: Probable nucleotide sugar dehydratase; ... 72 3e-11
UniRef50_Q97H47 Cluster: Nucleoside-diphosphate-sugar epimerase;... 71 3e-11
UniRef50_Q58M85 Cluster: Nucleotide-sugar epimerase; n=1; Cyanop... 71 3e-11
UniRef50_Q4CYB9 Cluster: GDP-mannose 4,6 dehydratase, putative; ... 71 3e-11
UniRef50_Q0F315 Cluster: DTDP-D-glucose 4,6-dehydratase; n=3; Pr... 71 5e-11
UniRef50_Q7UTP9 Cluster: UDP-glucose 4-epimerase homolog; n=2; P... 71 6e-11
UniRef50_A0JYE3 Cluster: NAD-dependent epimerase/dehydratase; n=... 71 6e-11
UniRef50_A2EQ76 Cluster: Putative uncharacterized protein; n=1; ... 70 8e-11
UniRef50_Q5UXR0 Cluster: UDP-glucose 4-epimerase; n=3; Halobacte... 70 8e-11
UniRef50_Q9WZ98 Cluster: Nucleotide sugar epimerase, putative; n... 70 1e-10
UniRef50_UPI0000E87F7E Cluster: probable nucleoside-diphosphate-... 69 1e-10
UniRef50_Q2LWN6 Cluster: NAD dependent epimerase/dehydratase fam... 69 1e-10
UniRef50_Q2AZL1 Cluster: NAD-dependent epimerase/dehydratase:3-b... 69 2e-10
UniRef50_Q1ILI4 Cluster: NAD-dependent epimerase/dehydratase pre... 69 2e-10
UniRef50_A2R6J0 Cluster: Catalytic activity: dTDPglucose = dTDP-... 69 2e-10
UniRef50_UPI0000384B58 Cluster: COG0451: Nucleoside-diphosphate-... 69 2e-10
UniRef50_Q93KW6 Cluster: Putative NDP-glucose 4-epimerase; n=1; ... 69 2e-10
UniRef50_A0GDZ4 Cluster: NAD-dependent epimerase/dehydratase; n=... 69 2e-10
UniRef50_Q8THQ2 Cluster: DTDP-glucose 4,6-dehydratase; n=15; Arc... 69 2e-10
UniRef50_Q982P5 Cluster: UDP-glucose 4-epimerase; n=1; Mesorhizo... 68 3e-10
UniRef50_Q54366 Cluster: LmbM protein; n=1; Streptomyces lincoln... 68 3e-10
UniRef50_A5TVF5 Cluster: dTDP-glucose 4,6-dehydratase; n=4; Fuso... 68 3e-10
UniRef50_A0L3Z4 Cluster: NAD-dependent epimerase/dehydratase; n=... 68 3e-10
UniRef50_Q9UXL5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Sulf... 68 3e-10
UniRef50_Q04973 Cluster: Vi polysaccharide biosynthesis protein ... 68 3e-10
UniRef50_Q81YX3 Cluster: NAD-dependent epimerase/dehydratase fam... 68 4e-10
UniRef50_Q6E7F2 Cluster: Fcf1; n=1; Escherichia coli|Rep: Fcf1 -... 68 4e-10
UniRef50_A0LGE9 Cluster: NAD-dependent epimerase/dehydratase; n=... 68 4e-10
UniRef50_Q97L35 Cluster: FUSION: Nucleoside-diphosphate-sugar ep... 67 6e-10
UniRef50_Q01T66 Cluster: DTDP-glucose 4,6-dehydratase precursor;... 67 6e-10
UniRef50_A1IA75 Cluster: CDP-tyvelose-2-epimerase; n=4; Bacteria... 67 6e-10
UniRef50_Q00TT7 Cluster: Nucleotide-sugar epimerase; n=2; Ostreo... 67 6e-10
UniRef50_P14169 Cluster: CDP-paratose 2-epimerase; n=12; cellula... 67 6e-10
UniRef50_A7TUR9 Cluster: Putative nucleoside-diphosphate-sugar e... 67 8e-10
UniRef50_Q8U170 Cluster: UDP-or dTTP-glucose 4-epimerase or 4-6-... 67 8e-10
UniRef50_Q9LIS3 Cluster: UDP-glucuronate 4-epimerase 6; n=40; Vi... 67 8e-10
UniRef50_Q2JCE7 Cluster: DTDP-glucose 4,6-dehydratase; n=5; Bact... 66 1e-09
UniRef50_Q1Q6W8 Cluster: Similar to uridine 5'-diphospho-glucose... 66 1e-09
UniRef50_Q11EM0 Cluster: NAD-dependent epimerase/dehydratase; n=... 66 1e-09
UniRef50_Q01CB4 Cluster: NAD-dependent epimerase/dehydratase; n=... 66 1e-09
UniRef50_Q7V0Q5 Cluster: Putative CDP-tyvelose-2-epimerase; n=1;... 66 1e-09
UniRef50_O06485 Cluster: YfnG; n=3; Bacteria|Rep: YfnG - Bacillu... 66 1e-09
UniRef50_Q1VUM7 Cluster: UDP-glucose 4-epimerase; n=1; Psychrofl... 66 1e-09
UniRef50_Q1FJC1 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Clos... 66 1e-09
UniRef50_A1GFD2 Cluster: NAD-dependent epimerase/dehydratase; n=... 66 1e-09
UniRef50_Q64PX7 Cluster: DTDP-glucose 4,6-dehydratase; n=10; Bac... 66 2e-09
UniRef50_P29782 Cluster: dTDP-glucose 4,6-dehydratase; n=65; Bac... 66 2e-09
UniRef50_Q2K5C6 Cluster: Probable UDP-glucose 4-epimerase protei... 65 2e-09
UniRef50_A3DED9 Cluster: DTDP-glucose 4,6-dehydratase; n=5; Clos... 65 2e-09
UniRef50_Q5UXR1 Cluster: UDP-glucose 4-epimerase; n=2; Halobacte... 65 2e-09
UniRef50_Q83WD7 Cluster: DTDP-glucose-4,6-dehydratase; n=4; Bact... 65 3e-09
UniRef50_Q9UZH2 Cluster: RfbB dTDP-glucose 4,6-dehydratase; n=27... 65 3e-09
UniRef50_Q31EZ4 Cluster: NAD-dependent epimerase/dehydratase fam... 64 4e-09
UniRef50_Q1IKV4 Cluster: NAD-dependent epimerase/dehydratase pre... 64 4e-09
UniRef50_A0FYZ6 Cluster: NAD-dependent epimerase/dehydratase; n=... 64 4e-09
UniRef50_Q7VFZ2 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 64 5e-09
UniRef50_Q04TJ8 Cluster: Glucose galactose epimerase; n=4; Lepto... 64 5e-09
UniRef50_O66157 Cluster: Deduced dNDP-hexose 4,6-dehydratase; n=... 64 5e-09
UniRef50_A3UAZ0 Cluster: NAD-dependent epimerase/dehydratase; n=... 64 5e-09
UniRef50_A3SGX4 Cluster: Putative epimerase/dehydratase; n=1; Su... 64 5e-09
UniRef50_Q018E1 Cluster: GDP-mannose 4,6 dehydratase; n=1; Ostre... 64 5e-09
UniRef50_Q18EM2 Cluster: Nucleoside-diphosphate-sugar epimerase;... 64 7e-09
UniRef50_Q8F9G0 Cluster: DTDP-glucose 4,6-dehydratase; n=4; Lept... 63 1e-08
UniRef50_Q661H6 Cluster: Nucleotide sugar epimerase; n=3; Borrel... 63 1e-08
UniRef50_Q6I4D4 Cluster: UDP-glucose 4-epimerase, C-terminus; n=... 62 2e-08
UniRef50_A3I4Y7 Cluster: Nucleoside-diphosphate-sugar epimerase ... 62 3e-08
UniRef50_A1VAD3 Cluster: NAD-dependent epimerase/dehydratase; n=... 62 3e-08
UniRef50_A7D6W0 Cluster: NAD-dependent epimerase/dehydratase; n=... 62 3e-08
UniRef50_P44914 Cluster: dTDP-glucose 4,6-dehydratase; n=117; Ba... 62 3e-08
UniRef50_Q7RYQ7 Cluster: Putative uncharacterized protein NCU004... 61 4e-08
UniRef50_P55293 Cluster: dTDP-glucose 4,6-dehydratase; n=265; ce... 61 4e-08
UniRef50_Q30XB3 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 61 5e-08
UniRef50_Q2JDH1 Cluster: NAD-dependent epimerase/dehydratase; n=... 61 5e-08
UniRef50_Q1IMR1 Cluster: NAD-dependent epimerase/dehydratase; n=... 61 5e-08
UniRef50_Q11WI1 Cluster: ADP-L-glycero-D-mannoheptose-6-epimeras... 61 5e-08
UniRef50_A4SFN8 Cluster: NAD-dependent epimerase/dehydratase; n=... 61 5e-08
UniRef50_A6FPS1 Cluster: NAD-dependent epimerase/dehydratase; n=... 60 7e-08
UniRef50_A0NYC5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Stap... 60 7e-08
UniRef50_A0JUA0 Cluster: NAD-dependent epimerase/dehydratase; n=... 60 7e-08
UniRef50_Q21Z09 Cluster: NAD-dependent epimerase/dehydratase; n=... 60 9e-08
UniRef50_Q11EL9 Cluster: NAD-dependent epimerase/dehydratase; n=... 60 9e-08
UniRef50_A0L9M4 Cluster: NAD-dependent epimerase/dehydratase; n=... 60 9e-08
UniRef50_A7D6Z2 Cluster: NAD-dependent epimerase/dehydratase; n=... 60 9e-08
UniRef50_UPI000065D9F2 Cluster: dTDP-D-glucose 4,6-dehydratase (... 60 1e-07
UniRef50_A5YSN9 Cluster: Nucleoside-diphosphate-sugar epimerase;... 60 1e-07
UniRef50_Q20697 Cluster: Putative uncharacterized protein; n=2; ... 59 2e-07
UniRef50_Q2H934 Cluster: Putative uncharacterized protein; n=2; ... 59 2e-07
UniRef50_Q8X7P7 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 59 2e-07
UniRef50_Q8ECF4 Cluster: DTDP-glucose 4,6-dehydratase; n=18; Gam... 59 2e-07
UniRef50_Q8CZD7 Cluster: Spore coat polysaccharide synthesis; n=... 59 2e-07
UniRef50_Q7NLE5 Cluster: Glr1179 protein; n=18; Bacteria|Rep: Gl... 59 2e-07
UniRef50_A5D3C1 Cluster: Nucleoside-diphosphate-sugar epimerases... 59 2e-07
UniRef50_A4QBQ2 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07
UniRef50_Q9YCT1 Cluster: DTDP-glucose 4,6-dehydratase; n=2; Ther... 59 2e-07
UniRef50_P55295 Cluster: dTDP-glucose 4,6-dehydratase; n=185; Ba... 59 2e-07
UniRef50_O54067 Cluster: UDP-glucuronate 5'-epimerase; n=163; ce... 59 2e-07
UniRef50_Q3ANB2 Cluster: Putative sugar nucleotide epimerase/deh... 58 3e-07
UniRef50_Q8KNN2 Cluster: DTDP-D-glucose-4,6-dehydratase; n=4; Ba... 58 3e-07
UniRef50_Q0C425 Cluster: DTDP-glucose 4,6-dehydratase; n=4; Prot... 58 3e-07
UniRef50_Q9HRD1 Cluster: UDP-glucose 4-epimerase; n=6; Euryarcha... 58 3e-07
UniRef50_Q0LJD8 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Herp... 58 3e-07
UniRef50_A5FSS2 Cluster: NAD-dependent epimerase/dehydratase; n=... 58 3e-07
UniRef50_Q9A8C4 Cluster: ADP-L-glycero-D-mannoheptose-6-epimeras... 58 5e-07
UniRef50_A7M5Y2 Cluster: Putative uncharacterized protein; n=1; ... 58 5e-07
UniRef50_Q8FSL0 Cluster: Putative GDP-D-mannose dehydratase; n=2... 57 6e-07
UniRef50_Q1MNV8 Cluster: Nucleoside-diphosphate-sugar epimerases... 57 6e-07
UniRef50_Q1GN57 Cluster: NAD-dependent epimerase/dehydratase; n=... 57 6e-07
UniRef50_O05384 Cluster: DNA for glycosyltransferase, lytic tran... 57 6e-07
UniRef50_A5V019 Cluster: NAD-dependent epimerase/dehydratase; n=... 57 6e-07
UniRef50_A4AB66 Cluster: Glucose 4-epimerase; n=1; Congregibacte... 57 6e-07
UniRef50_P95780 Cluster: dTDP-glucose 4,6-dehydratase; n=123; Ba... 57 6e-07
UniRef50_A7DIX5 Cluster: NAD-dependent epimerase/dehydratase; n=... 57 8e-07
UniRef50_A6BHF2 Cluster: Putative uncharacterized protein; n=1; ... 57 8e-07
UniRef50_Q2RUA8 Cluster: UDP-glucose 4-epimerase precursor; n=1;... 56 1e-06
UniRef50_Q2BI20 Cluster: NDP-sugar dehydratase or epimerase; n=1... 56 1e-06
UniRef50_A6L7F6 Cluster: UDP-GlcNAc 4-epimerase; n=3; Bacteroide... 56 1e-06
UniRef50_A6GA52 Cluster: NAD(P)H steroid dehydrogenase; n=1; Ple... 56 1e-06
UniRef50_Q97BK3 Cluster: NDP-sugar epimerase; n=3; cellular orga... 56 1e-06
UniRef50_Q0S8T5 Cluster: UDP-glucose 4-epimerase; n=25; Actinoba... 56 1e-06
UniRef50_A3HU61 Cluster: Dihydroflavonol 4-reductase; n=1; Algor... 56 1e-06
UniRef50_A1B7X9 Cluster: NAD-dependent epimerase/dehydratase; n=... 56 1e-06
UniRef50_A0K0K9 Cluster: NAD-dependent epimerase/dehydratase; n=... 56 1e-06
UniRef50_A6UU12 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 56 1e-06
UniRef50_Q8NBZ7 Cluster: UDP-glucuronic acid decarboxylase 1; n=... 56 1e-06
UniRef50_Q5U756 Cluster: UDP-galactose 4-epimerase; n=1; Acidith... 56 2e-06
UniRef50_A0R4U4 Cluster: NAD dependent epimerase/dehydratase fam... 56 2e-06
UniRef50_UPI0001597850 Cluster: hypothetical protein RBAM_031220... 55 2e-06
UniRef50_Q2J7B4 Cluster: NAD-dependent epimerase/dehydratase; n=... 55 2e-06
UniRef50_Q2MFI4 Cluster: Putative apramycin biosynthetic oxidore... 55 2e-06
UniRef50_Q1AZZ2 Cluster: NAD-dependent epimerase/dehydratase; n=... 55 2e-06
UniRef50_A5UQ88 Cluster: NAD-dependent epimerase/dehydratase; n=... 55 2e-06
UniRef50_A7QPG5 Cluster: Chromosome chr18 scaffold_137, whole ge... 55 2e-06
UniRef50_Q1IJY8 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 55 3e-06
UniRef50_A5UZF7 Cluster: NAD-dependent epimerase/dehydratase; n=... 55 3e-06
UniRef50_Q2FS05 Cluster: NAD-dependent epimerase/dehydratase; n=... 55 3e-06
UniRef50_A3H6D1 Cluster: NAD-dependent epimerase/dehydratase; n=... 55 3e-06
UniRef50_A7HFB6 Cluster: NAD-dependent epimerase/dehydratase; n=... 54 4e-06
UniRef50_A3CRA1 Cluster: DTDP-4-dehydrorhamnose 3,5-epimerase, p... 54 6e-06
UniRef50_A0UW76 Cluster: NAD-dependent epimerase/dehydratase; n=... 54 6e-06
UniRef50_Q4Q8W9 Cluster: GDP-mannose 4,6 dehydratase, putative; ... 54 6e-06
UniRef50_A6UI88 Cluster: Polysaccharide biosynthesis protein Cap... 54 7e-06
UniRef50_A3J1V9 Cluster: Putative capsular biosynthesis protein;... 54 7e-06
UniRef50_A3CQX3 Cluster: Nucleotide sugar dehydratase, putative;... 54 7e-06
UniRef50_Q96VM0 Cluster: Putative dTDP-glucose 4,6-dehydratase; ... 54 7e-06
UniRef50_Q8GJ79 Cluster: DTDP glucose-4,6-dehydrogenase; n=11; B... 53 1e-05
UniRef50_Q1GK00 Cluster: NAD-dependent epimerase/dehydratase; n=... 53 1e-05
UniRef50_A6TTQ2 Cluster: NAD-dependent epimerase/dehydratase; n=... 53 1e-05
UniRef50_Q97A88 Cluster: DTDP-glucose 4,6-dehydratase; n=2; cell... 53 1e-05
UniRef50_Q5V3C6 Cluster: DTDP-glucose dehydratase; n=23; cellula... 53 1e-05
UniRef50_Q73MR8 Cluster: Epimerase/dehydratase, putative; n=2; B... 53 1e-05
UniRef50_Q5FQJ4 Cluster: GDP-6-deoxy-D-lyxo-4-hexulose reductase... 52 2e-05
UniRef50_Q0FS47 Cluster: UDP-glucose 4-epimerase; n=1; Roseovari... 52 2e-05
UniRef50_A6PTN5 Cluster: NAD-dependent epimerase/dehydratase pre... 52 2e-05
UniRef50_A1IBU5 Cluster: Nucleoside-diphosphate-sugar epimerases... 52 2e-05
UniRef50_Q984R2 Cluster: DTDP-glucose 4-6-dehydratase; n=8; Prot... 52 2e-05
UniRef50_Q7UVP4 Cluster: DTDP-glucose-4,6-dehydratase; n=1; Pire... 52 2e-05
UniRef50_Q0AZA7 Cluster: Nucleoside-diphosphate-sugar epimerase ... 52 2e-05
UniRef50_A6QAJ4 Cluster: dTDP-glucose 4,6-dehydratase; n=1; Sulf... 52 2e-05
UniRef50_A5UPL7 Cluster: NAD-dependent epimerase/dehydratase; n=... 52 2e-05
UniRef50_A4ALH8 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q8PRA9 Cluster: Degenerated UDP-glucose epimerase; n=1;... 52 3e-05
UniRef50_Q474T2 Cluster: NAD-dependent epimerase/dehydratase:3-b... 52 3e-05
UniRef50_Q30V12 Cluster: UDP-glucose 4-epimerase precursor; n=1;... 52 3e-05
UniRef50_Q7BR89 Cluster: GDP-6-deoxy-4-keto-D-mannose-3, 5-epime... 52 3e-05
UniRef50_Q26CF0 Cluster: Capsular polysaccharide biosynthesis pr... 52 3e-05
UniRef50_A7GZ40 Cluster: dTDP-glucose 4,6-dehydratase; n=1; Camp... 52 3e-05
UniRef50_A4YQ54 Cluster: Bifunctional GDP-fucose synthetase: GDP... 52 3e-05
UniRef50_A1ZEA9 Cluster: NAD-dependent epimerase/dehydratase; n=... 52 3e-05
UniRef50_Q8UJL3 Cluster: UDP-glucose 4-epimerase; n=3; Rhizobiac... 51 4e-05
UniRef50_Q67G37 Cluster: Probable dTDP-4-keto-6-deoxyhexose redu... 51 4e-05
UniRef50_Q1VPF4 Cluster: Putative capsular polysaccharide biosyn... 51 4e-05
UniRef50_A3V6A3 Cluster: Epimerase/dehydratase, putative; n=1; L... 51 4e-05
UniRef50_A1SL10 Cluster: NAD-dependent epimerase/dehydratase; n=... 51 4e-05
UniRef50_A0ABY0 Cluster: Putative NAD(P)H steroid dehydrogenase;... 51 4e-05
UniRef50_Q5UYK6 Cluster: UDP-glucose 4-epimerase; n=2; Haloarcul... 51 4e-05
UniRef50_Q4TH04 Cluster: Chromosome undetermined SCAF3339, whole... 51 5e-05
UniRef50_Q5FRE3 Cluster: Putative oxidoreductase; n=1; Gluconoba... 51 5e-05
UniRef50_Q0PHX8 Cluster: RfbB; n=1; Spirochaeta aurantia|Rep: Rf... 51 5e-05
UniRef50_Q2NGX2 Cluster: Predicted nucleoside-diphosphate-sugar ... 51 5e-05
UniRef50_Q6GMH6 Cluster: LOC553532 protein; n=30; Gnathostomata|... 50 7e-05
UniRef50_Q98K10 Cluster: UDP-galactose 4-epimerase; n=23; cellul... 50 7e-05
UniRef50_Q89HI4 Cluster: GalE protein; n=4; Bacteria|Rep: GalE p... 50 7e-05
UniRef50_Q2CH75 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Ocea... 50 7e-05
UniRef50_Q1QSK3 Cluster: NAD-dependent epimerase/dehydratase; n=... 50 7e-05
UniRef50_Q0PV99 Cluster: RfbB; n=2; Rhizobiaceae|Rep: RfbB - Rhi... 50 7e-05
UniRef50_A4CKE2 Cluster: Putative capsular polysaccharide biosyn... 50 7e-05
UniRef50_Q54262 Cluster: StrP protein; n=5; Actinomycetales|Rep:... 50 9e-05
UniRef50_Q0B0C5 Cluster: Polysaccharide biosynthesis protein Cap... 50 9e-05
UniRef50_A3DII3 Cluster: CDP-glucose 4,6-dehydratase; n=4; Bacte... 50 9e-05
UniRef50_A7I972 Cluster: NAD-dependent epimerase/dehydratase; n=... 50 9e-05
UniRef50_A1RUM8 Cluster: NAD-dependent epimerase/dehydratase; n=... 50 9e-05
UniRef50_Q47GM1 Cluster: NAD-dependent epimerase/dehydratase:3-b... 50 1e-04
UniRef50_Q2LWK8 Cluster: UDP-N-acetylglucosamine 4,6-dehydratase... 50 1e-04
UniRef50_Q0AKI5 Cluster: Polysaccharide biosynthesis protein Cap... 50 1e-04
UniRef50_A5V0L7 Cluster: NAD-dependent epimerase/dehydratase; n=... 50 1e-04
UniRef50_Q0UY12 Cluster: Putative uncharacterized protein; n=1; ... 50 1e-04
UniRef50_Q5V4R9 Cluster: UDP-glucose 4-epimerase; n=3; Halobacte... 50 1e-04
UniRef50_Q1GGJ8 Cluster: NAD-dependent epimerase/dehydratase; n=... 49 2e-04
UniRef50_A6Q4T4 Cluster: NAD-dependent epimerase/dehydratase; n=... 49 2e-04
UniRef50_Q7SH36 Cluster: Putative uncharacterized protein NCU026... 49 2e-04
UniRef50_Q84HD2 Cluster: NDP-hexose-4-ketoreductase; n=4; Strept... 49 2e-04
UniRef50_Q8EZD0 Cluster: NAD(P)-dependent steroid dehydrogenase;... 48 3e-04
UniRef50_Q7UVQ0 Cluster: UDP-glucose 4-epimerase; n=1; Pirellula... 48 3e-04
UniRef50_Q6EB26 Cluster: Tgh114; n=10; Bacteria|Rep: Tgh114 - Ca... 48 3e-04
UniRef50_A4EVQ8 Cluster: NAD-dependent epimerase/dehydratase fam... 48 3e-04
UniRef50_A3XLL6 Cluster: Putative oxidoreductase protein; n=1; L... 48 3e-04
UniRef50_A3W0V3 Cluster: NAD-dependent epimerase/dehydratase fam... 48 3e-04
UniRef50_A3U613 Cluster: NAD-dependent epimerase/dehydratase fam... 48 3e-04
UniRef50_Q1MMR7 Cluster: Putative CDP-glucose 4,6-dehydratase; n... 48 4e-04
UniRef50_Q0M0M9 Cluster: NAD-dependent epimerase/dehydratase:3-b... 48 4e-04
UniRef50_Q09SL2 Cluster: WbmG; n=3; Bordetella|Rep: WbmG - Borde... 48 4e-04
UniRef50_O87265 Cluster: Oxidoreductase Rmd; n=8; Pseudomonas|Re... 48 4e-04
UniRef50_A4AQN1 Cluster: NAD-dependent epimerase/dehydratase:Sho... 48 4e-04
UniRef50_A3TQF4 Cluster: Probable dtdp-glucose 4,6-dehydratase t... 48 4e-04
UniRef50_A0YNT9 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04
UniRef50_Q74FI1 Cluster: GDP-fucose synthetase; n=7; Bacteria|Re... 48 5e-04
UniRef50_Q47PG2 Cluster: UDP-glucose 4-epimerase; n=1; Thermobif... 48 5e-04
UniRef50_Q2S4Y8 Cluster: Nucleoside-diphosphate-sugar epimerase;... 48 5e-04
UniRef50_Q2NQC7 Cluster: Putative sugar-nucleotide epimerase/deh... 48 5e-04
UniRef50_Q8GP51 Cluster: Eps11G; n=11; Bacteria|Rep: Eps11G - St... 48 5e-04
UniRef50_Q41GE9 Cluster: UDP-glucose 4-epimerase; n=1; Exiguobac... 48 5e-04
UniRef50_Q01WZ5 Cluster: Polysaccharide biosynthesis protein Cap... 48 5e-04
UniRef50_A6Q744 Cluster: NAD-dependent epimerase/dehydratase; n=... 48 5e-04
UniRef50_A5UUD9 Cluster: NAD-dependent epimerase/dehydratase; n=... 48 5e-04
UniRef50_A3I1Z8 Cluster: Putative UDP-galactose 4-epimerase; n=1... 48 5e-04
UniRef50_A0M2V5 Cluster: Capsular polysaccharide biosynthesis pr... 48 5e-04
UniRef50_O28263 Cluster: UDP-glucose 4-epimerase; n=1; Archaeogl... 48 5e-04
UniRef50_Q7VZF5 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 48 5e-04
UniRef50_Q81AP5 Cluster: CDP-abequose synthase; n=2; Bacillus ce... 47 6e-04
UniRef50_Q6N2K1 Cluster: Cdp-glucose 4,6-dehydratase; n=13; Prot... 47 6e-04
UniRef50_Q3BRW4 Cluster: NAD(P)H steroid dehydrogenase; n=4; Xan... 47 6e-04
UniRef50_Q3B1R9 Cluster: GDP-L-fucose synthetase; n=3; Bacteria|... 47 6e-04
UniRef50_Q12PG8 Cluster: 3-beta hydroxysteroid dehydrogenase/iso... 47 6e-04
UniRef50_A7IHZ6 Cluster: NAD-dependent epimerase/dehydratase pre... 47 6e-04
UniRef50_A2R589 Cluster: Contig An15c0120, complete genome; n=5;... 47 6e-04
UniRef50_UPI000050F8BF Cluster: COG1086: Predicted nucleoside-di... 47 9e-04
UniRef50_Q9K8W1 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus ... 47 9e-04
UniRef50_Q8CUH9 Cluster: Spore coat polysaccharide synthesis; n=... 47 9e-04
UniRef50_Q888L1 Cluster: GDP-6-deoxy-D-lyxo-4-hexulose reductase... 47 9e-04
UniRef50_Q30PV2 Cluster: NAD-dependent epimerase/dehydratase; n=... 47 9e-04
UniRef50_Q2SII8 Cluster: Nucleoside-diphosphate-sugar epimerase;... 47 9e-04
UniRef50_Q2S5K3 Cluster: Epimerase/reductase, putative; n=1; Sal... 47 9e-04
UniRef50_Q9ZHQ3 Cluster: 4-ketoreductase; n=2; Actinomycetales|R... 47 9e-04
UniRef50_Q1K1K0 Cluster: 3-beta hydroxysteroid dehydrogenase/iso... 47 9e-04
UniRef50_A6LP17 Cluster: NAD-dependent epimerase/dehydratase; n=... 47 9e-04
UniRef50_Q54XR1 Cluster: Putative uncharacterized protein; n=1; ... 47 9e-04
UniRef50_A1D6E5 Cluster: Nucleoside-diphosphate-sugar epimerase,... 47 9e-04
UniRef50_Q58461 Cluster: Uncharacterized membrane protein MJ1061... 47 9e-04
UniRef50_Q6MRE5 Cluster: Dihydroflavonol-4-reductase; n=2; Bdell... 46 0.001
UniRef50_Q316B8 Cluster: NAD-dependent epimerase/dehydratase fam... 46 0.001
UniRef50_Q07LQ2 Cluster: NAD-dependent epimerase/dehydratase pre... 46 0.001
UniRef50_A3PE76 Cluster: Nucleotide-diphosphate-sugar epimerase,... 46 0.001
UniRef50_A7DQV7 Cluster: Polysaccharide biosynthesis protein Cap... 46 0.001
UniRef50_Q1AYI6 Cluster: NAD-dependent epimerase/dehydratase; n=... 46 0.001
UniRef50_Q1AXH3 Cluster: NAD-dependent epimerase/dehydratase; n=... 46 0.001
UniRef50_Q0PHZ5 Cluster: SpaM; n=1; Spirochaeta aurantia|Rep: Sp... 46 0.001
UniRef50_A7NHE9 Cluster: Polysaccharide biosynthesis protein Cap... 46 0.001
UniRef50_A6LIJ9 Cluster: Putative dTDP-glucose 4-6-dehydratase; ... 46 0.001
UniRef50_A6EMI0 Cluster: 3-beta hydroxysteroid dehydrogenase/iso... 46 0.001
UniRef50_Q22945 Cluster: Putative uncharacterized protein; n=3; ... 46 0.001
UniRef50_Q9L8S5 Cluster: SqdC; n=5; Rhizobiales|Rep: SqdC - Rhiz... 46 0.002
UniRef50_Q7WNH4 Cluster: Putative NAD dependent epimerase/dehydr... 46 0.002
UniRef50_Q4BX31 Cluster: Similar to Nucleoside-diphosphate-sugar... 46 0.002
UniRef50_Q08T32 Cluster: GDP-6-deoxy-D-lyxo-4-hexulose reductase... 46 0.002
UniRef50_A1VGT7 Cluster: NAD-dependent epimerase/dehydratase; n=... 46 0.002
UniRef50_UPI0000E49416 Cluster: PREDICTED: hypothetical protein;... 45 0.003
UniRef50_Q98H87 Cluster: Mll2981 protein; n=27; Bacteria|Rep: Ml... 45 0.003
UniRef50_Q2RI44 Cluster: NAD-dependent epimerase/dehydratase; n=... 45 0.003
UniRef50_A6PLI6 Cluster: dTDP-4-dehydrorhamnose reductase; n=1; ... 45 0.003
UniRef50_A1UIF1 Cluster: NAD-dependent epimerase/dehydratase; n=... 45 0.003
UniRef50_A0LKB4 Cluster: Polysaccharide biosynthesis protein Cap... 45 0.003
UniRef50_A7DQT2 Cluster: NAD-dependent epimerase/dehydratase; n=... 45 0.003
UniRef50_P53199 Cluster: Sterol-4-alpha-carboxylate 3-dehydrogen... 45 0.003
UniRef50_Q8R6F9 Cluster: UDP-N-acetyl-D-quinovosamine 4-epimeras... 45 0.003
UniRef50_Q74FC2 Cluster: Dihydroflavonol 4-reductase, putative; ... 45 0.003
UniRef50_Q6MMD8 Cluster: UDP-N-acetyl-D-quinovosamine 4-epimeras... 45 0.003
UniRef50_Q2KC62 Cluster: Probable nucleoside-diphosphate-sugar e... 45 0.003
UniRef50_Q4E8F1 Cluster: NAD-dependent epimerase/dehydratase fam... 45 0.003
UniRef50_Q2BI22 Cluster: DTDP-glucose dehydratase; n=1; Neptunii... 45 0.003
UniRef50_A5CYW8 Cluster: Nucleoside-diphosphate-sugar epimerases... 45 0.003
UniRef50_A2BSE2 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003
UniRef50_A0NNV5 Cluster: Putative nucleotide sugar epimerase deh... 45 0.003
UniRef50_Q23086 Cluster: Putative uncharacterized protein; n=2; ... 45 0.003
UniRef50_A6NKP2 Cluster: Uncharacterized protein ENSP00000330812... 45 0.003
UniRef50_Q0CRI8 Cluster: Predicted protein; n=2; Aspergillus|Rep... 45 0.003
UniRef50_Q3KPY4 Cluster: MGC131206 protein; n=6; Gnathostomata|R... 44 0.005
UniRef50_Q814Z6 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 44 0.005
UniRef50_Q6MAT7 Cluster: Putative ADP-D-beta-heptose epimerase, ... 44 0.005
>UniRef50_Q14376 Cluster: UDP-glucose 4-epimerase; n=150; cellular
organisms|Rep: UDP-glucose 4-epimerase - Homo sapiens
(Human)
Length = 348
Score = 410 bits (1009), Expect = e-113
Identities = 200/353 (56%), Positives = 249/353 (70%), Gaps = 9/353 (2%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M+ VLVTGGAGY+GSHTV+ LLE + P VV+DN NA+ G PE+L+R++E
Sbjct: 1 MAEKVLVTGGAGYIGSHTVLELLE--AGYLP---VVIDNFHNAFRGGGSL-PESLRRVQE 54
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
LTG++V F ++DI AL R+F+ ++ VIHFA LKAVGESV+KPL+YY+VN+ GT
Sbjct: 55 LTGRSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQ 114
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L EIM+ HGV LV+SSS TVYG P+YLP++E+HPTG T+PYGKSK+F EE+++DLC
Sbjct: 115 LLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTG-GCTNPYGKSKFFIEEMIRDLCQ 173
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+DK W + LRYFNP GAH SG IGEDP GIPNNLMPY+SQVA+GR + L VFG+DY T
Sbjct: 174 ADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTE 233
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DGTGVRDYIHV DLA GH+ A++ + G NLGTGTGYSVL+MV A ASG
Sbjct: 234 DGTGVRDYIHVVDLAKGHIAALRKLKEQ--CGCRIYNLGTGTGYSVLQMVQAMEKASGKK 291
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
GDV A A+ +LA LGW A L MC D WRWQ+ NP+G+
Sbjct: 292 IPYKVVARREGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGF 344
>UniRef50_P18645 Cluster: UDP-glucose 4-epimerase; n=353; cellular
organisms|Rep: UDP-glucose 4-epimerase - Rattus
norvegicus (Rat)
Length = 347
Score = 388 bits (956), Expect = e-107
Identities = 194/352 (55%), Positives = 237/352 (67%), Gaps = 10/352 (2%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M VLVTGGAGY+GSHTV+ LLE + P VV+DN N+ E + PE+L+R++E
Sbjct: 1 MEEKVLVTGGAGYIGSHTVLELLE--AGYSP---VVIDNFHNSIRGE-DSMPESLRRVQE 54
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
LTG++V F ++DI AL +F+ HN VIHFA LKAVGESV+KPL+YY+VN+ GT
Sbjct: 55 LTGRSVEFEEMDILDQAALQHLFKKHNFKAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQ 114
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L EIMR GV LV+SSS TVYG+P +P + P + T PYGKSK+F EE+++DLC
Sbjct: 115 LLEIMRAMGVKSLVFSSSATVYGKP--VPASGRGPPHRGCTKPYGKSKFFIEEMIQDLCR 172
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+D W + LRYF P+GAH S RIGEDP GIPNNLMPY+SQVA+GR + L VFGDDY T
Sbjct: 173 ADTAWNAVLLRYFIPIGAHRSARIGEDPQGIPNNLMPYVSQVAIGRREALNVFGDDYATE 232
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DGTGVRDYIHV DLA GH+ A+K + G NLGTGTGYSVL+MV A ASG
Sbjct: 233 DGTGVRDYIHVVDLAKGHIAALKKLKEQ--CGCRIYNLGTGTGYSVLQMVQAMEKASGKK 290
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNG 352
GDV A A+ +LA LGW A L MC D WRWQ+ NP+G
Sbjct: 291 IPYKVVARREGDVAACYANPSLAHEELGWTAALGLDRMCEDLWRWQKQNPSG 342
>UniRef50_O54385 Cluster: UDP-glucose epimerase; n=11; cellular
organisms|Rep: UDP-glucose epimerase - Brucella abortus
Length = 335
Score = 366 bits (901), Expect = e-100
Identities = 183/349 (52%), Positives = 230/349 (65%), Gaps = 17/349 (4%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAGY+GSHT + L+E E+VVVDN N++ PEAL RIE++TG+
Sbjct: 3 ILVTGGAGYIGSHTCVQLIEAGH-----EVVVVDNFDNSH-------PEALHRIEKITGR 50
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
DIR ++++ + H VIHFA LKAVGES EKPL YY N+ GT L +
Sbjct: 51 APRREPGDIRDRALMEQVIKRHKCTAVIHFAGLKAVGESSEKPLLYYDCNVLGTLRLLQA 110
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
M GV KLV+SSS TVYG+P+ LPI E P S T+PYG++K E++++DL SD
Sbjct: 111 MEATGVKKLVFSSSATVYGDPDKLPITEDQPL--SATNPYGRTKLVIEDMLRDLYNSDNS 168
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
WAI LRYFNPVGAHESG IGEDP GIPNNLMP I+QVA GR ++L ++G+DYPT DGTG
Sbjct: 169 WAIAILRYFNPVGAHESGLIGEDPKGIPNNLMPIIAQVATGRREKLNIWGNDYPTPDGTG 228
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
VRDYIHV DLAAGH++A+K +P A+NLGTG GYSVL+++ AF + S
Sbjct: 229 VRDYIHVNDLAAGHLKALKKLDKP---KCFAVNLGTGQGYSVLDVIKAFEHVSNREIKYE 285
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
GDV AD A + LGW A ++L +MC+D W WQ NPNGY
Sbjct: 286 IAPRRPGDVAECYADPGFAKKFLGWSAEKNLREMCQDMWNWQSKNPNGY 334
>UniRef50_Q9T0A7 Cluster: Probable UDP-glucose 4-epimerase
At4g23920; n=58; cellular organisms|Rep: Probable
UDP-glucose 4-epimerase At4g23920 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 350
Score = 356 bits (875), Expect = 6e-97
Identities = 184/354 (51%), Positives = 223/354 (62%), Gaps = 12/354 (3%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M+++VLVTGGAGY+GSHTV+ LLE VVVDN N+ A ++ +K++
Sbjct: 1 MAKSVLVTGGAGYIGSHTVLQLLE-----GGYSAVVVDNYDNSSAASLQR----VKKLAG 51
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
G + F++VD+R AL++IF D VIHFA LKAVGESVEKPL YY NI GT T
Sbjct: 52 ENGNRLSFHQVDLRDRPALEKIFSETKFDAVIHFAGLKAVGESVEKPLLYYNNNIVGTVT 111
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L E+M ++G LV+SSS TVYG P+ +P E P S T+PYG++K F EEI +D+
Sbjct: 112 LLEVMAQYGCKNLVFSSSATVYGWPKEVPCTEESPI--SATNPYGRTKLFIEEICRDVHR 169
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
SD +W II LRYFNPVGAH SG IGEDP G+PNNLMPY+ QVAVGR L VFG DY T
Sbjct: 170 SDSEWKIILLRYFNPVGAHPSGYIGEDPLGVPNNLMPYVQQVAVGRRPHLTVFGTDYKTK 229
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DGTGVRDYIHV DLA GH+ A++ + NLGTG G SVLEMVAAF ASG
Sbjct: 230 DGTGVRDYIHVMDLADGHIAALRKLDDLKIS-CEVYNLGTGNGTSVLEMVAAFEKASGKK 288
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGYH 354
GD A A R L W+A + +MCRD W W NP GY+
Sbjct: 289 IPLVMAGRRPGDAEVVYASTEKAERELNWKAKNGIEEMCRDLWNWASNNPYGYN 342
>UniRef50_Q42605 Cluster: UDP-glucose 4-epimerase; n=20;
Viridiplantae|Rep: UDP-glucose 4-epimerase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 351
Score = 343 bits (842), Expect = 6e-93
Identities = 179/354 (50%), Positives = 225/354 (63%), Gaps = 20/354 (5%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG- 63
+LVTGGAG++G+HTV+ LL+ D ++ ++DN N+ EA+ R+ EL G
Sbjct: 9 ILVTGGAGFIGTHTVVQLLK-----DGFKVSIIDNFDNSVI-------EAVDRVRELVGP 56
Query: 64 ---KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
K + F D+R ++++F D VIHFA LKAVGESVE P Y+ N+ GT
Sbjct: 57 DLSKKLDFNLGDLRNKGDIEKLFSKQRFDAVIHFAGLKAVGESVENPRRYFDNNLVGTIN 116
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L+E M K+ +V+SSS TVYG+PE +P E K++ +PYG++K F EEI +D+
Sbjct: 117 LYETMAKYNCKMMVFSSSATVYGQPEKIPCMEDFEL-KAM-NPYGRTKLFLEEIARDIQK 174
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
++ +W II LRYFNPVGAHESG IGEDP GIPNNLMPYI QVAVGRL EL V+G DYPT
Sbjct: 175 AEPEWRIILLRYFNPVGAHESGSIGEDPKGIPNNLMPYIQQVAVGRLPELNVYGHDYPTE 234
Query: 241 DGTGVRDYIHVCDLAAGHVQAI-KLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
DG+ VRDYIHV DLA GH+ A+ KLF P G A NLGTG G SVLEMVAAF ASG
Sbjct: 235 DGSAVRDYIHVMDLADGHIAALRKLFADPKI-GCTAYNLGTGQGTSVLEMVAAFEKASGK 293
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
GD TA A A + LGW+A + +MCRD W+W NP GY
Sbjct: 294 KIPIKLCPRRSGDATAVYASTEKAEKELGWKAKYGVDEMCRDQWKWANNNPWGY 347
>UniRef50_A5M424 Cluster: UDP-glucose 4-epimerase; n=1;
Streptococcus pneumoniae SP11-BS70|Rep: UDP-glucose
4-epimerase - Streptococcus pneumoniae SP11-BS70
Length = 342
Score = 341 bits (837), Expect = 2e-92
Identities = 155/351 (44%), Positives = 235/351 (66%), Gaps = 12/351 (3%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+++L+TGGAGY+GSHTV+ LL+ E+ ++D+LSN+ +K E++K+I + +
Sbjct: 2 KSLLITGGAGYIGSHTVLDLLDNN-----YEVTIIDDLSNSK----KKVIESIKQISKKS 52
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
+ +HFYK+D++ E L+ +F+ HN D VIHFA KAVGESV +PL+YY+ N+ T +
Sbjct: 53 -RNLHFYKIDLKNEEKLENVFKRHNFDGVIHFAGYKAVGESVVEPLKYYENNLLSTINIL 111
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
++M+K+ V+ V+SSS TVY +P E++P S +PYG++K + E ++ DL +S+
Sbjct: 112 KLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKAS--NPYGRTKQYIEVLLNDLFISN 169
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
W I+ LRYFNP+GAHESG +GEDP+GIPNNL+PYI+QVA+G+L L +FG DY T DG
Sbjct: 170 SNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLNIFGVDYSTPDG 229
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
T +RDY+HV DLA GH +A++ + INLG+G G+SV E++ + + G
Sbjct: 230 TCIRDYVHVNDLAYGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEILHSLESVIGSYIP 289
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
GD+ ++AD++ A LGW+ + MC+DTW+WQ+ +PNGY
Sbjct: 290 YKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQKHPNGY 340
>UniRef50_Q8H931 Cluster: Putative UDP-glucose 4-epimerase; n=5;
Oryza sativa|Rep: Putative UDP-glucose 4-epimerase -
Oryza sativa subsp. japonica (Rice)
Length = 408
Score = 334 bits (822), Expect = 2e-90
Identities = 174/354 (49%), Positives = 218/354 (61%), Gaps = 17/354 (4%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R VLVTGGAGY+GSH V+ LL VVVDNL+N+ A++R+ L
Sbjct: 12 RTVLVTGGAGYIGSHAVLQLLLAG-----FRAVVVDNLNNS-------SELAVRRVAALA 59
Query: 63 G---KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTC 119
G + + F+KVD+R AL+++F + D V+HFA LKAVGESV+KPL YY ++NGT
Sbjct: 60 GDHSRNLAFHKVDLRDKGALEKVFASTRFDAVVHFAGLKAVGESVQKPLLYYDNSVNGTV 119
Query: 120 TLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC 179
L E+M HG KLV+SSS VYG P+ P E P + +PYGK+K E+I +D+
Sbjct: 120 NLLEVMSAHGCKKLVFSSSAAVYGSPKNSPWTEEFPLTPN--NPYGKTKLVVEDICRDIY 177
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+D +W II LRYFNPVGAH SG +GEDP GIPNNLMPY+ QVAVGR L + G+DY T
Sbjct: 178 RTDPEWKIILLRYFNPVGAHPSGYLGEDPCGIPNNLMPYVQQVAVGRRPALTILGNDYAT 237
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
DGTGVRDYIHV DLA GH+ A++ + G A NLGTG G SVLE+V AF ASG
Sbjct: 238 RDGTGVRDYIHVVDLADGHIAALQKLFESSSIGCEAYNLGTGKGTSVLEIVKAFEKASGK 297
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
GD + A A + L W+A + +MCRD W W NP GY
Sbjct: 298 KIPLIIGPRRPGDAEILFSLPAKAEKELNWKAKFGIDEMCRDQWNWASKNPYGY 351
>UniRef50_P04397 Cluster: Bifunctional protein GAL10 [Includes:
UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase);
Aldose 1-epimerase (EC 5.1.3.3) (Mutarotase)]; n=187;
cellular organisms|Rep: Bifunctional protein GAL10
[Includes: UDP-glucose 4-epimerase (EC 5.1.3.2)
(Galactowaldenase); Aldose 1-epimerase (EC 5.1.3.3)
(Mutarotase)] - Saccharomyces cerevisiae (Baker's yeast)
Length = 699
Score = 322 bits (790), Expect = 1e-86
Identities = 173/359 (48%), Positives = 221/359 (61%), Gaps = 21/359 (5%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL 61
S+ VLVTGGAGY+GSHTV+ L+E D VV DNLSN+ +++ R+E L
Sbjct: 11 SKIVLVTGGAGYIGSHTVVELIENGYD-----CVVADNLSNSTY-------DSVARLEVL 58
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
T + FY+VD+ + L+++F+ + ID VIHFA LKAVGES + PL YY NI GT L
Sbjct: 59 TKHHIPFYEVDLCDRKGLEKVFKEYKIDSVIHFAGLKAVGESTQIPLRYYHNNILGTVVL 118
Query: 122 FEIMRKHGVYKLVYSSSCTVYGE----PEYLPINESHPTGKSLTSPYGKSKYFCEEIMKD 177
E+M+++ V K V+SSS TVYG+ P +PI E P G T+PYG +KY E I+ D
Sbjct: 119 LELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGP--TNPYGHTKYAIENILND 176
Query: 178 LCVSDKK-WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDD 236
L SDKK W LRYFNP+GAH SG IGEDP GIPNNL+PY++QVAVGR ++L +FGDD
Sbjct: 177 LYNSDKKSWKFAILRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDD 236
Query: 237 YPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFN-GF-HAINLGTGTGYSVLEMVAAFS 294
Y + DGT +RDYIHV DLA GH+ A++ N G NLG+G G +V E+ AF
Sbjct: 237 YDSRDGTPIRDYIHVVDLAKGHIAALQYLEAYNENEGLCREWNLGSGKGSTVFEVYHAFC 296
Query: 295 NASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
ASG GDV A A R L W+ + D C+D W+W NP GY
Sbjct: 297 KASGIDLPYKVTGRRAGDVLNLTAKPDRAKRELKWQTELQVEDSCKDLWKWTTENPFGY 355
>UniRef50_Q7VAY9 Cluster: UDP-glucose 4-epimerase; n=2;
Prochlorococcus marinus|Rep: UDP-glucose 4-epimerase -
Prochlorococcus marinus
Length = 347
Score = 320 bits (787), Expect = 3e-86
Identities = 171/357 (47%), Positives = 226/357 (63%), Gaps = 24/357 (6%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT-G 63
+LVTGGAG++GSHT ITLLE D ++++D+ N+ +LKR++E++
Sbjct: 4 ILVTGGAGFIGSHTCITLLESGYD-----LLIIDSFINS-------SEVSLKRVKEMSDN 51
Query: 64 KTVHFYKVDIRCAEALDRIFEN-----HNIDCVIHFAALKAVGESVEKPLEYYQVNINGT 118
K +++ K DIR E LD IF N ID VIHFA LK+V ES + PL Y+ VN+ G+
Sbjct: 52 KNINYLKGDIRNLEFLDSIFSNAIQEGKPIDAVIHFAGLKSVSESTKIPLTYWDVNVVGS 111
Query: 119 CTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL 178
LF IMRK+ Y +V+SSS T+YG + +PI E S +PYG+SK E+I+ DL
Sbjct: 112 IALFSIMRKYKCYTIVFSSSATIYGNTDKVPIKEDSLI--SPINPYGESKATVEKILSDL 169
Query: 179 CVSDK-KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDY 237
+S W I LRYFNPVGAH SGRIGEDP GIPNNL PYI+ VA G++K+++VFG+D+
Sbjct: 170 SLSAPFDWRIACLRYFNPVGAHPSGRIGEDPLGIPNNLFPYITNVAGGQIKQVEVFGNDW 229
Query: 238 PTADGTGVRDYIHVCDLAAGHVQAIK-LFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNA 296
PT DGTGVRDY+HV DLA H A++ LF +P +NLG G G SVLE++ FS
Sbjct: 230 PTQDGTGVRDYVHVLDLAEAHKSALECLFAEPA--QLLILNLGNGFGLSVLEIINTFSRV 287
Query: 297 SGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
+ GD+ + AD+AL+ L W RS+ DMCRDTWRW+ NP GY
Sbjct: 288 NNCEVPYVFAARRPGDIAISYADIALSKARLNWYPKRSIEDMCRDTWRWKLNNPIGY 344
>UniRef50_UPI0000DAE763 Cluster: hypothetical protein
Rgryl_01001156; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01001156 - Rickettsiella
grylli
Length = 341
Score = 314 bits (772), Expect = 2e-84
Identities = 163/353 (46%), Positives = 213/353 (60%), Gaps = 15/353 (4%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M +LVTGG G++GSH + + IV++DNL N+Y E + R+E
Sbjct: 1 MPSVILVTGGTGFIGSHVCVAFANAGYN-----IVILDNLRNSYF-------EVVDRLEC 48
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+ + F + DI + LD IF +NI VIH A LKAV ES++ PL+ Y N+ GT T
Sbjct: 49 ICKFRLKFIEGDILDSNLLDHIFFENNISAVIHLAGLKAVSESIKNPLKCYNNNVEGTLT 108
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L MRK V KL++SSS VYGEP+ +PI E+ P S +PY +SK E I+ DL
Sbjct: 109 LINAMRKSNVKKLIFSSSAAVYGEPKCVPIRENFPL--SPINPYARSKLMVENILTDLHH 166
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
++ W I+ LRYFNPVGAHESG IGEDP +NLMPY++QVA+GR K+ +FG +YPT
Sbjct: 167 AEPDWHIVCLRYFNPVGAHESGLIGEDPKKFTHNLMPYLTQVAIGRSKQFNIFGGNYPTV 226
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DGT +RDYIHV DLA GHV A+ + G +NL TG G SVLE++ AF+ +
Sbjct: 227 DGTAIRDYIHVMDLAEGHVAALSNYTN-WKRGVLTVNLSTGKGLSVLEVLRAFTEFNQCK 285
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
GDV AD A R L W+A RSL +C+D+WRWQ+ANPNGY
Sbjct: 286 IAYRILDRRPGDVAECWADPTNAQRILNWKARRSLAQICKDSWRWQKANPNGY 338
>UniRef50_A5GHV3 Cluster: UDP-glucose-4-epimerase; n=11;
Cyanobacteria|Rep: UDP-glucose-4-epimerase -
Synechococcus sp. (strain WH7803)
Length = 351
Score = 312 bits (767), Expect = 7e-84
Identities = 164/357 (45%), Positives = 223/357 (62%), Gaps = 22/357 (6%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG- 63
+LVTGGAG++GSHT + LLE +G ++V +DN SN+ ++L RI+ELT
Sbjct: 3 ILVTGGAGFIGSHTCLRLLE---EGH--QVVSIDNYSNSTV-------QSLTRIKELTSS 50
Query: 64 ---KTVHFYKVDIRCAEALDRIF---ENHNIDCVIHFAALKAVGESVEKPLEYYQVNING 117
+ + DIR + L + F + ID VIHFA LK+VGES++KPL+Y+ +N+NG
Sbjct: 51 VNTQNLKIIDGDIRRSVDLFKAFNCLDGKEIDAVIHFAGLKSVGESMKKPLKYWDINVNG 110
Query: 118 TCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKD 177
T L M KHG LV+SSSCTVYG + INE+ +PYG++K E+++ D
Sbjct: 111 TSNLLMAMSKHGCKTLVFSSSCTVYGTSKQKKINEASTIAP--INPYGRTKAAVEQMLLD 168
Query: 178 LCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDY 237
SD +W I LRYFNPVGAH SG IGEDP G P NL P++ QVA + K+L +FG+D+
Sbjct: 169 QFNSDPQWRICCLRYFNPVGAHPSGHIGEDPKGTPGNLFPFLMQVAKKQRKKLNIFGNDW 228
Query: 238 PTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNAS 297
PTADGT +RDYIH+ DL GH+ A++ + + A+NLGTG G SVLE V+AF A+
Sbjct: 229 PTADGTCIRDYIHILDLVDGHLAALRFLCEEA-PQWLAVNLGTGIGVSVLEFVSAFEQAT 287
Query: 298 GXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGYH 354
G GD VAD ++A + L W+ RSL D+C D W+WQ ANPNG++
Sbjct: 288 GLVVPYEFVERRAGDAAVAVADPSVALKKLKWKPVRSLRDICIDGWKWQNANPNGFN 344
>UniRef50_A0VUL2 Cluster: UDP-glucose 4-epimerase; n=2;
Rhodobacterales|Rep: UDP-glucose 4-epimerase -
Dinoroseobacter shibae DFL 12
Length = 359
Score = 307 bits (753), Expect = 3e-82
Identities = 169/348 (48%), Positives = 213/348 (61%), Gaps = 16/348 (4%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M++ +L+TGGAGY+GSHT + L ++ G E+V++D+ SNA P+ R+E
Sbjct: 1 MTQTILLTGGAGYIGSHTYVAL---KAAG--FEVVILDDFSNA----ARDVPD---RLEL 48
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+TG V Y+ + L R+F ID V+HFAA KAVGESV PL Y++ N G
Sbjct: 49 ITGAPVRLYEGSVLDRGLLARLFTETRIDAVVHFAARKAVGESVAMPLAYFETNCTGLVG 108
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L + M V++LV+SSS TVYG P+ P E+ P +PYG +K E I+ L
Sbjct: 109 LLQEMEAACVHRLVFSSSATVYGIPDVTPTPETAPHRHM--NPYGLTKITGELILDALAT 166
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
SD KWA +LRYFNP GAH S IGEDPS IPNNLMPYI+QVA+G+ L+VFGDDYPT
Sbjct: 167 SDPKWAFGTLRYFNPAGAHGSALIGEDPSDIPNNLMPYIAQVAMGQRPHLQVFGDDYPTP 226
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DGTGVRDYIHV DLA GHV ++K + G + H +NLGTG GYSVLEMVAA+S A G
Sbjct: 227 DGTGVRDYIHVEDLAEGHVLSLKSLLETGES--HLVNLGTGRGYSVLEMVAAYSAACGRA 284
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEA 348
GDV A V A LG+ A R L MC +W W +A
Sbjct: 285 LPYRIVDRRPGDVPIYCATVERARALLGFEAKRDLAQMCASSWAWIQA 332
>UniRef50_Q0IDK5 Cluster: UDP-glucose 4-epimerase; n=3;
Cyanobacteria|Rep: UDP-glucose 4-epimerase -
Synechococcus sp. (strain CC9311)
Length = 370
Score = 295 bits (725), Expect = 9e-79
Identities = 168/373 (45%), Positives = 219/373 (58%), Gaps = 30/373 (8%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEA----LKRIE- 59
+L+TGGAG++GSHT + LLE +++V+D+ SN+ E+ E L+R +
Sbjct: 4 LLITGGAGFIGSHTCLVLLEAGH-----QLLVLDDFSNSSAIALERVAELAGARLQRDQP 58
Query: 60 --ELTGKTVHFYKVDIRCAEALDRIFENHN-----IDCVIHFAALKAVGESVEKPLEYYQ 112
+T+ + DIR A+ LD +F + I+ VIHFA LKAVGESV++PL Y+
Sbjct: 59 TLRAAPETLTLVEGDIRDAQCLDALFTSTKTFDQPIEAVIHFAGLKAVGESVQQPLRYWD 118
Query: 113 VNINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCE 172
VN+ G+ L M +H LV+SSS T+YG P+ +PI E+ P +PYG SK E
Sbjct: 119 VNVVGSQRLLSAMDRHSCRTLVFSSSATLYGYPDQVPIPETAPIQP--INPYGASKQAAE 176
Query: 173 EIMKDLC----------VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQV 222
+ D+ S W I LRYFNPVGAH SGRIGEDP+GIPNNL P+I+QV
Sbjct: 177 ALFADIAGCSGKPEPIQASQGGWRIARLRYFNPVGAHPSGRIGEDPNGIPNNLFPFITQV 236
Query: 223 AVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGT 282
A+GR EL VFGDD+PT DGTGVRDYIHV DLA GH +A+ +NLG+G
Sbjct: 237 AIGRRPELTVFGDDWPTPDGTGVRDYIHVMDLAEGHREALHSLLNTD-PQLLTLNLGSGQ 295
Query: 283 GYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDT 342
G SVL++V A AS GD VA+ LA + L WR RSL ++CRD
Sbjct: 296 GASVLDVVKAMEAASQRAIPYRIAPRRPGDAALTVANPTLAAQHLHWRTQRSLAEICRDG 355
Query: 343 WRWQEANPNGYHR 355
W WQ+ANP GY R
Sbjct: 356 WAWQQANPQGYIR 368
>UniRef50_Q7MX67 Cluster: UDP-glucose 4-epimerase; n=12;
Bacteroidetes|Rep: UDP-glucose 4-epimerase -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 342
Score = 292 bits (717), Expect = 8e-78
Identities = 156/350 (44%), Positives = 205/350 (58%), Gaps = 16/350 (4%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M + +LVTGG GY+GSHT + L Q G +V VDN SN+ A L I
Sbjct: 1 MKQKILVTGGTGYIGSHTTVEL---QQAG--YRVVSVDNFSNSNAA-------VLDGIAR 48
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENH-NIDCVIHFAALKAVGESVEKPLEYYQVNINGTC 119
+TG FY+ D EA++R+F H +I VIHFAA KAVGESV+KPL YY+ NI
Sbjct: 49 ITGVRPDFYEADCNDTEAMERVFTAHPDIAGVIHFAASKAVGESVQKPLLYYRNNILSLL 108
Query: 120 TLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC 179
+ E+M + G +V+SSSCTVYG+PE LP+ E P ++L SPYG +K EEI++D
Sbjct: 109 NILELMERFGTRGIVFSSSCTVYGQPEVLPVTEEAPIQEAL-SPYGNTKQINEEIIRDAI 167
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+ + I LRYFNP+GAH + IGE P+G+P NL+PY++Q A G EL VFGDDY T
Sbjct: 168 HAGAGYKAILLRYFNPIGAHPTAHIGELPNGVPQNLIPYLTQTAAGIRAELSVFGDDYDT 227
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIK--LFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNAS 297
DG+ +RDYI+V DLA HV AI+ L + + N+GTG G SVLE++ F +
Sbjct: 228 PDGSCIRDYIYVVDLAKAHVAAIERMLNEEKASDSLEVFNIGTGRGVSVLELIRTFERVT 287
Query: 298 GXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQE 347
G GD+ A+ A LGW+A SL D WRWQ+
Sbjct: 288 GVAVPHRIVGRREGDIEQVWAEPKKANEVLGWKALESLEDTLLSAWRWQQ 337
>UniRef50_A1ZWK4 Cluster: UDP-glucose 4-epimerase; n=16;
Bacteroidetes|Rep: UDP-glucose 4-epimerase - Microscilla
marina ATCC 23134
Length = 351
Score = 292 bits (717), Expect = 8e-78
Identities = 158/352 (44%), Positives = 211/352 (59%), Gaps = 22/352 (6%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VL+TGG G++GSHTVI+L++ + L V+VDN N+ P L+ +E++TG
Sbjct: 3 VLITGGTGFIGSHTVISLVK-----EGLNPVIVDNFDNS-------SPYILEALEKITGT 50
Query: 65 TVHFYKVDIRCAEALDRIF-ENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
FY VD A+ALD++F + NI VIHFAA KAVGESV PL+YY+ N+ L +
Sbjct: 51 KPSFYNVDCNDAQALDQVFMQEGNIQGVIHFAAHKAVGESVANPLKYYRNNLGSLINLLD 110
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD- 182
M +H V LV+SSSCTVYG+P LP+ E+ + SPYG +K CEEI+KD S+
Sbjct: 111 PMLRHKVSSLVFSSSCTVYGQPATLPVTETAAVVPA-ASPYGNTKQVCEEIIKDTVASNV 169
Query: 183 -----KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDY 237
+ LRYFNP+GAH SG+IGE P G+P NL+P+I+Q A G +L VFG+DY
Sbjct: 170 LNPEQSAMNAVLLRYFNPIGAHPSGQIGELPLGVPGNLVPFITQTAAGIRPQLTVFGNDY 229
Query: 238 PTADGTGVRDYIHVCDLAAGHVQAIKL-FHQPGFNGF-HAINLGTGTGYSVLEMVAAFSN 295
T DGT +RDYIHV DLA HV+A++ + G A N+GTG G+SV+E+V F
Sbjct: 230 NTPDGTCIRDYIHVLDLADAHVKALRFAANVADKKGLCEAFNIGTGKGHSVMELVKTFEQ 289
Query: 296 ASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQE 347
SG GD+ A V A + LGW A R + + RD W WQ+
Sbjct: 290 VSGLSLNYLLGERRSGDIEQIYASVDKAQQQLGWVAQRDIEEGLRDAWNWQK 341
>UniRef50_A4QBQ0 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium glutamicum R|Rep: Putative
uncharacterized protein - Corynebacterium glutamicum
(strain R)
Length = 335
Score = 278 bits (681), Expect = 2e-73
Identities = 146/343 (42%), Positives = 201/343 (58%), Gaps = 17/343 (4%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGG G++GSHTV+ LL ++VV+D+LSN+ + L IEE+TG
Sbjct: 8 VLVTGGTGFIGSHTVVELLNAGK-----QVVVIDDLSNSTI-------DVLASIEEITGS 55
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
DIR +D + + IHFAA KAVGESVE+P Y +NI GT TL +
Sbjct: 56 KPPLEIGDIRDRAFVDSVLAQYQPSAAIHFAAKKAVGESVEQPTMYLNINIGGTATLLDA 115
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+ GV +V+SSSC+V+GE + P+NE PT + +PY +K E+++ L +D+
Sbjct: 116 LHHAGVRDIVFSSSCSVHGETTHSPLNEDSPTQPA--NPYAFTKLTGEKMLSQLVEADES 173
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
W+ ISLRYFNP+GAH SG++GE G P N+MP++ VA GR + L+VFGDD+PT DGT
Sbjct: 174 WSAISLRYFNPIGAHPSGKLGESGLGRPRNIMPWLLDVAAGRKQSLEVFGDDWPTPDGTC 233
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
+RDY+HV D+A HV+A++ F F N+GTG G SVLE++ A+G
Sbjct: 234 IRDYLHVVDVARVHVRALEHFKTGQAEVF---NIGTGVGTSVLELINTMEEATGREIPYE 290
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQE 347
GDV+A VAD GW S+ MC D WR+ +
Sbjct: 291 ISARRSGDVSALVADAQRVATQWGWVPEFSVFQMCADAWRFDQ 333
>UniRef50_Q5QPP4 Cluster: UDP-galactose-4-epimerase; n=6; cellular
organisms|Rep: UDP-galactose-4-epimerase - Homo sapiens
(Human)
Length = 239
Score = 277 bits (678), Expect = 4e-73
Identities = 128/200 (64%), Positives = 156/200 (78%), Gaps = 2/200 (1%)
Query: 71 VDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGV 130
+DI AL R+F+ ++ VIHFA LKAVGESV+KPL+YY+VN+ GT L EIM+ HGV
Sbjct: 1 MDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGV 60
Query: 131 YKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISL 190
LV+SSS TVYG P+YLP++E+HPTG T+PYGKSK+F EE+++DLC +DK W + L
Sbjct: 61 KNLVFSSSATVYGNPQYLPLDEAHPTG-GCTNPYGKSKFFIEEMIRDLCQADKTWNAVLL 119
Query: 191 RYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIH 250
RYFNP GAH SG IGEDP GIPNNLMPY+SQVA+GR + L VFG+DY T DGTGVRDYIH
Sbjct: 120 RYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIH 179
Query: 251 VCDLAAGHVQAI-KLFHQPG 269
V DLA GH+ A+ KL Q G
Sbjct: 180 VVDLAKGHIAALRKLKEQCG 199
>UniRef50_Q5K809 Cluster: Galactose metabolism-related protein,
putative; n=7; Basidiomycota|Rep: Galactose
metabolism-related protein, putative - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 390
Score = 274 bits (671), Expect = 3e-72
Identities = 166/383 (43%), Positives = 224/383 (58%), Gaps = 47/383 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGG GY+GSH V++LL G L IV+ DN NAY P+AL+R ++
Sbjct: 19 VLVTGGLGYIGSHVVLSLL---MSGRYLPIVI-DNAHNAY-------PQALERCNQIAQS 67
Query: 65 TV--H-----FYKVDIRCAEALDRIFENHN----IDCVIHFAALKAVGESVEKPLEYYQV 113
V H +++ DIR AE ++++F+ + I VIH AALKAVGES E PL+YY+V
Sbjct: 68 EVGPHAPKPLYHQCDIRNAEEINKVFKQYQSKGGIWAVIHLAALKAVGESSEIPLDYYEV 127
Query: 114 NINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEE 173
N+ G+ +L +IM++ LV+SSS TVYG P +PI E+ S YG++K EE
Sbjct: 128 NVGGSISLLKIMQQSQTNNLVFSSSATVYGTPAVIPIPETSEIIPE--SVYGRTKAITEE 185
Query: 174 IMKDLC------VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRL 227
+++D+C ++ IS+RYFNP GAH SG++GE+P G P NL+P ++Q+AVGRL
Sbjct: 186 VIRDVCRAGAATADNQGLKAISVRYFNPAGAHPSGKLGEEPKGRPGNLLPILAQIAVGRL 245
Query: 228 -KELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQA--------IKLFHQPGFNG------ 272
+LKVFG+DYPT DGT +RDY+H+ DLA GH+ A IK F
Sbjct: 246 SSDLKVFGNDYPTRDGTCLRDYLHIMDLAEGHLLALDALAKSEIKTQSSGIFQSIDTKKE 305
Query: 273 --FHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWR 330
F A NLG G G +VLEM+ A+G GDV AD LA LG+
Sbjct: 306 GYFRAFNLGRGKGITVLEMINEMKIATGYEYQFEIVERRSGDVPDLTADPRLAQEELGFI 365
Query: 331 ATRSLHDMCRDTWRWQEANPNGY 353
A R L +MC+D WR+Q +N NGY
Sbjct: 366 ARRGLQEMCQDLWRFQSSNVNGY 388
>UniRef50_Q1MP11 Cluster: Nucleoside-diphosphate-sugar epimerases;
n=1; Lawsonia intracellularis PHE/MN1-00|Rep:
Nucleoside-diphosphate-sugar epimerases - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 339
Score = 266 bits (651), Expect = 8e-70
Identities = 143/346 (41%), Positives = 194/346 (56%), Gaps = 17/346 (4%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+ +LVTGG GY+GSH VI L+ + +V VDNL N+ + + IE +
Sbjct: 2 KKILVTGGLGYLGSHMVIELIY-----NGYTVVCVDNLHNS-------SEDIVYFIESIV 49
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
+ + F K ++ ++ +F + D VIHFA K++ ES++ PLEYYQ N N T T+
Sbjct: 50 KEKIEFVKANVEDTSMMEVLFSKYTFDAVIHFAGYKSIAESLKIPLEYYQNNYNSTLTIL 109
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
+ K+ ++SSS TVYG P+YLP+ E HP + +PYGK+K E+I+ D+ +
Sbjct: 110 RLCLKYNS-TFIFSSSATVYGIPQYLPLTEEHPL--AAINPYGKTKLHIEQIIFDVANAY 166
Query: 183 KKWAIISLRYFNPVGAHESGRI-GEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ LRYFNPVG G I GE P N+MP I QVA G KE+ +FGDDY T D
Sbjct: 167 PMFNAFILRYFNPVGGGGKGFILGEHSKNAPTNVMPIICQVAAGIQKEIYIFGDDYETID 226
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GTGVRDYIHV DL AGH+ A+K + G H NLGTG G SVLE++ F +
Sbjct: 227 GTGVRDYIHVTDLIAGHMAALKKAEE-NKTGCHIYNLGTGKGISVLELIHTFEKVNNISV 285
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQE 347
GDV + AD A R L W+A + L DM D+W WQ+
Sbjct: 286 PYCVVARRSGDVASCYADPTKAFRELNWKAQKGLEDMVYDSWLWQK 331
>UniRef50_A3PE72 Cluster: UDP-glucose 4-epimerase; n=2;
Prochlorococcus marinus|Rep: UDP-glucose 4-epimerase -
Prochlorococcus marinus (strain MIT 9301)
Length = 352
Score = 264 bits (647), Expect = 2e-69
Identities = 134/359 (37%), Positives = 200/359 (55%), Gaps = 13/359 (3%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M++ +LVTGGAG++GSHT + LLE ++VV+D+ N+ E+ + L
Sbjct: 1 MNKIILVTGGAGFIGSHTCLLLLE-----SGYKVVVIDSFINSSLNSLERVKKILISDNN 55
Query: 61 LTGKTVHFYKVDIRCAEALDRIF-----ENHNIDCVIHFAALKAVGESVEKPLEYYQVNI 115
+ K D+R E ++ IF ID VIHFA LK + ES+ P+ Y++ N+
Sbjct: 56 FFSNRLKIVKGDLRDFECINNIFLKYKINKEKIDGVIHFAGLKNIKESISDPISYWENNV 115
Query: 116 NGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIM 175
GT L + M + +++SS+ +YG+ E E+ + KS +PYG++K E+++
Sbjct: 116 TGTINLLKAMHHNNCNSIIFSSTAALYGKSESKVFKET--SIKSPINPYGETKLAIEKLL 173
Query: 176 KDLCVSD-KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFG 234
DL S+ W I +LRYFNP+G H SG+IGE P P N+ P I + A +K++ +FG
Sbjct: 174 NDLYKSNPNSWKIANLRYFNPIGCHNSGQIGESPLNKPTNIFPLIIKAASKEIKKISIFG 233
Query: 235 DDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFS 294
+D+PT DGTG+RDYIHV DLA GH++AI+ +NLG G G SVLE++ F+
Sbjct: 234 NDWPTHDGTGIRDYIHVMDLAEGHIKAIEFLMSKNKGNLINLNLGRGVGVSVLELINTFT 293
Query: 295 NASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
+ GDV ++AD LA L W R + +MC D W+W+ NP GY
Sbjct: 294 KVNNVNIEYEFAERREGDVPISIADNCLAKTLLNWCPKRDIEEMCIDGWKWKLLNPKGY 352
>UniRef50_Q5QXD9 Cluster: UDP-glucose 4-epimerase; n=1; Idiomarina
loihiensis|Rep: UDP-glucose 4-epimerase - Idiomarina
loihiensis
Length = 335
Score = 260 bits (637), Expect = 4e-68
Identities = 140/347 (40%), Positives = 198/347 (57%), Gaps = 19/347 (5%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M + +LVTGG G++GSHTV+ L+ +++V+D+LSN+ + + +I+
Sbjct: 1 MKKQILVTGGCGFIGSHTVVELIL-----SGYQVIVIDDLSNSNAS-------VIDKIQC 48
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+TG+ F++VDI +AL ++F+ + D V+HFAALK ES +Y+ N+ GT
Sbjct: 49 ITGERPEFHQVDICNRDALTKLFKQYAFDAVMHFAALKNPQESYHLKEKYFLTNVEGTRR 108
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L +M V L++SSS VYG P +P+ ES P G + T+PYG++KY E + + C
Sbjct: 109 LLAVMEDCSVNHLIFSSSAVVYGNPSCVPVAESAPAGAT-TNPYGENKYRSECDLAEFCE 167
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+ ++ ISLRYFNP GAH SG IGE P NL+P I V ++ ++V+G DY T
Sbjct: 168 KNLAFSAISLRYFNPAGAHPSGVIGEQPIKPAANLIPAIGNVITRKVDSVQVYGGDYSTC 227
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGF--NGFHAINLGTGTGYSVLEMVAAFSNASG 298
DGT +RDYIHVCD+A GHV A+ + GF G H NLGTG G SVL ++ AF ASG
Sbjct: 228 DGTAIRDYIHVCDVAKGHVAAL----EAGFARTGHHIFNLGTGKGESVLGVIHAFEQASG 283
Query: 299 XXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV + A A + L WRA L + RD W
Sbjct: 284 QIIPVNFSERRQGDVASCYAQADKALQELNWRAEHDLQTIARDYCHW 330
>UniRef50_UPI00006CC433 Cluster: UDP-glucose 4-epimerase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
UDP-glucose 4-epimerase family protein - Tetrahymena
thermophila SB210
Length = 369
Score = 260 bits (636), Expect = 5e-68
Identities = 138/364 (37%), Positives = 211/364 (57%), Gaps = 17/364 (4%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLE-----IVVVDNLSNAYCAEGEKKPEALK 56
+ +L+TGG G++GSHT + L + ++ + + I ++DNLSN + K LK
Sbjct: 8 TETILLTGGLGFIGSHTCVELYKYITEKNLTQNVHYKIAILDNLSNCMPSVENKIRTILK 67
Query: 57 R-IEELTGKTVH-FYKVDIRCAEALDRIFEN-----HNIDCVIHFAALKAVGESVEKPLE 109
E+ K F+ +D+ +AL+++F++ N++ +IHFA KAVGESV+ P+
Sbjct: 68 ESYPEVDEKEFFSFHNIDVLDLDALNKMFQSFADKRENVNFIIHFAGKKAVGESVKNPIL 127
Query: 110 YYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKY 169
Y++ N+ GT L +++ K + ++SS+ TVYGE + N + Y ++K
Sbjct: 128 YFENNVCGTLNLMKMVEKFQIKNFIFSSTATVYGETD----NCDEDNLLNPLQSYAQTKT 183
Query: 170 FCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKE 229
CE +MK +C + ++ LRYFNP GAH SG IG+ PS PNNL P++ QV +G+ ++
Sbjct: 184 CCEFLMKAMCAAHPSVRMVCLRYFNPAGAHSSGLIGDSPSVYPNNLFPFLEQVVIGKREK 243
Query: 230 LKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIK-LFHQPGFNGFHAINLGTGTGYSVLE 288
L +FG+DY T DGTGVRD+IHV DLA H+ AI L F AIN+GTG+G SVL+
Sbjct: 244 LYIFGNDYNTYDGTGVRDFIHVVDLACAHISAIDYLSKLNDTKNFEAINIGTGSGISVLD 303
Query: 289 MVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEA 348
V +S G GDV VA A++ L W+A ++L D+CRD++ + +
Sbjct: 304 TVTTYSKVIGRQIPYEFTKRRDGDVGQLVAKAEKASKILNWKAVKTLEDICRDSYNFIQK 363
Query: 349 NPNG 352
NPNG
Sbjct: 364 NPNG 367
>UniRef50_Q8R8R8 Cluster: UDP-glucose 4-epimerase; n=15;
Bacteria|Rep: UDP-glucose 4-epimerase -
Thermoanaerobacter tengcongensis
Length = 329
Score = 253 bits (619), Expect = 6e-66
Identities = 145/355 (40%), Positives = 207/355 (58%), Gaps = 31/355 (8%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
A+LV GGAGY+GSH V LL+R E+VVVDNL+ + E++ L G
Sbjct: 2 AILVCGGAGYIGSHAVYALLKRNE-----EVVVVDNLATGHS-------ESV-----LGG 44
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
K Y D+R + LD++F ++I+ V+HFAA VGESVE P +YY+ N+ GT +L +
Sbjct: 45 K---LYIGDLRDEDFLDKVFSENDIEAVMHFAASSLVGESVENPFKYYENNVCGTLSLLK 101
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
M+KHGV K+V+SS+ VYGEPE +PI E T T+PYG++K E+++K +D
Sbjct: 102 AMKKHGVKKIVFSSTAAVYGEPERIPIEEEDRT--EPTNPYGETKLAIEKMLK---WADA 156
Query: 184 KWAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ I ++LRYFN GA E+G IGED S +L+P I QVA+G+ ++ ++GDDYPT D
Sbjct: 157 AYGIKYVALRYFNVAGALETGEIGEDHSP-ETHLIPIILQVALGKRDKVMIYGDDYPTKD 215
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GT +RDYIHV DL H+ A++ + N NLG G G++V E++ +G
Sbjct: 216 GTPIRDYIHVMDLVDAHILALEKLRKE--NKSEVYNLGNGEGFTVKEVIEVARKVTGHPI 273
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQEANPNGYHR 355
GD VA A + LGWR SL ++ + W W + +PNG+ R
Sbjct: 274 PAEVTGRRPGDPAVLVASSEKAMKDLGWRPKYASLEEIIKSAWMWHKNHPNGFKR 328
>UniRef50_A2BSF0 Cluster: UDP-glucose 4-epimerase; n=1;
Prochlorococcus marinus str. AS9601|Rep: UDP-glucose
4-epimerase - Prochlorococcus marinus (strain AS9601)
Length = 355
Score = 251 bits (615), Expect = 2e-65
Identities = 140/350 (40%), Positives = 206/350 (58%), Gaps = 16/350 (4%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEAL-KRIEEL 61
+ VL TGG GY+GSHTVI L+ R ++++D+L N+ + L + E+
Sbjct: 2 KTVLTTGGLGYIGSHTVIALINRG-----FNVLIIDSLINSKSETFNNIEKILFNEMGEI 56
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHN-----IDCVIHFAALKAVGESVEKPLEYYQVNIN 116
K + F K D+R L+ IF+ N I+ VIHFA LK++GES+ PL YY VN+N
Sbjct: 57 KEK-LFFRKGDLRNKLWLENIFQEFNDKKQPIEAVIHFAGLKSIGESILNPLNYYDVNLN 115
Query: 117 GTCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMK 176
T L +M K +KL++SSS TVY + I+E+ S +PYG +K E+I++
Sbjct: 116 TTLCLLSVMSKFKCFKLIFSSSATVYKIDKNEKISENGIL--SPLNPYGNTKLSNEKIIE 173
Query: 177 DLCVSD-KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGD 235
D+ SD K+W I +LRYFNP GAH+SG IGE+P +N+ P I +V +++L ++G
Sbjct: 174 DVFKSDDKRWKIANLRYFNPCGAHDSGIIGENPLINHSNIFPTILRVINREIEKLPIYGS 233
Query: 236 DYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSN 295
D+PT DGT +RDYIHV DLA H+ A+ ++ + +N+GTGTG SVLE++ FSN
Sbjct: 234 DWPTKDGTCIRDYIHVMDLAEAHLAAL-IYLYENEPTYLNLNIGTGTGISVLELIKTFSN 292
Query: 296 ASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
+ GD VA+ +L ++L W R+L D+C+D+WRW
Sbjct: 293 VNNCQIPYYFTEKRKGDAAFVVANNSLVIQTLKWEPKRNLKDICKDSWRW 342
>UniRef50_Q9KDV3 Cluster: UDP-glucose 4-epimerase; n=124; cellular
organisms|Rep: UDP-glucose 4-epimerase - Bacillus
halodurans
Length = 334
Score = 249 bits (610), Expect = 7e-65
Identities = 145/351 (41%), Positives = 201/351 (57%), Gaps = 27/351 (7%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
A+LVTGGAGY+GSHTV+ LLE+ G+ +++V+DNL + + ++T
Sbjct: 2 AILVTGGAGYIGSHTVLFLLEQ---GE--QVIVLDNLQKGHAGA----------LSDVT- 45
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
FY DIR + LD IF H+ID VIHFAA VGESV++P+EYY+ N+ GT TL +
Sbjct: 46 ----FYHGDIRDDQLLDTIFTTHSIDTVIHFAANSLVGESVKQPIEYYENNVIGTHTLLK 101
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
M +H V K+V+SS+ YGEP +PI ES PT T+PYG++K E+ M C
Sbjct: 102 KMLEHDVKKIVFSSTAATYGEPVQIPIQESDPT--IPTNPYGETKLAIEK-MFHWCQEAY 158
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
+ LRYFN GA +GRIGED S ++L+P + QVA+G+ + + +FGDDY T DG+
Sbjct: 159 GLQYVCLRYFNAAGADPNGRIGEDHSP-ESHLIPIVLQVALGQRERVAIFGDDYQTEDGS 217
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
+RDYIHV DLA H A + + G +G + NLG G G+SV E++ +G
Sbjct: 218 CIRDYIHVMDLANAHYLACEHLRKDGQSG--SFNLGNGKGFSVKEVIEVCRQVTGHPIPA 275
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQEANPNGY 353
GD + +A A LGW SL M W W + +P+GY
Sbjct: 276 EIAPRRSGDPASLIASSEKAQTILGWEPKYPSLETMVEHAWNWHKEHPHGY 326
>UniRef50_A6RJ24 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 436
Score = 247 bits (604), Expect = 4e-64
Identities = 147/374 (39%), Positives = 197/374 (52%), Gaps = 39/374 (10%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LV GG G++GSHTV L + + + ++DNLSN++ EK + + K
Sbjct: 61 ILVVGGLGFIGSHTVWELAKAGYN-----VAIIDNLSNSFFTVFEKLQLMVDQHYSAPRK 115
Query: 65 TVH-----FYKVDIRCAEALDRIFENHN---------------------IDCVIHFAALK 98
H F+ D R + I E ++ I VIHFAA K
Sbjct: 116 NGHRPLLKFHDADFRDMNKMTAILEKYDYPGVMSFDSSSVTLCNGQRSSISGVIHFAAYK 175
Query: 99 AVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGE--PEYLPINESHPT 156
AV ES++ PL+YY N+ G ++++ G+ K+V+SSS TVYG +P+ E +
Sbjct: 176 AVEESIQHPLKYYSNNVGGLVDFCALLQQFGIKKMVFSSSATVYGTVADTGVPLREEYVV 235
Query: 157 GKS---LTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPN 213
G LT+PYG++K+ CE I+ DL SD W I +LRYFNP+G ESG +GEDP
Sbjct: 236 GSGCSGLTNPYGRTKWMCEAILSDLANSDPDWEITALRYFNPIGCDESGLLGEDPRAAAT 295
Query: 214 NLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGF 273
NLMP + +V G L L V+G DY T DGT VRDYIHV DLA GH+ A L ++P GF
Sbjct: 296 NLMPVVLRVLTGALPALNVYGSDYDTHDGTAVRDYIHVTDLARGHLAA--LSNRPS-GGF 352
Query: 274 HAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATR 333
NLGTG GYSVL++V A A+ GDV VA A L W+ +
Sbjct: 353 KVYNLGTGQGYSVLDVVNAMEKATQTKIPTNIVGRRGGDVGKCVALANKAEEELMWKTEK 412
Query: 334 SLHDMCRDTWRWQE 347
SL D C D WR+ E
Sbjct: 413 SLEDCCNDLWRFLE 426
>UniRef50_Q2UPV8 Cluster: UDP-glucose 4-epimerase; n=7;
Trichocomaceae|Rep: UDP-glucose 4-epimerase -
Aspergillus oryzae
Length = 428
Score = 241 bits (591), Expect = 1e-62
Identities = 142/375 (37%), Positives = 202/375 (53%), Gaps = 41/375 (10%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEK-KPEALKRIE 59
+ + +LVTGG G++GSHT + LL+ + ++V+DNLSNA+ ++ K A K E
Sbjct: 45 LDQYILVTGGLGFIGSHTTLELLKANYN-----VIVIDNLSNAFQNVFDRIKLLASKHHE 99
Query: 60 ELTGKT--VHFYKVDIRCAEALDRIFENHNIDC-----------VIHFAALKAVGESVEK 106
+ K +H + D R + AL ++ E + I VIHFAA KAV ES+
Sbjct: 100 QQGTKMPEMHLHAHDYRDSVALRKLLEQYQIQSRWGTPKTKISGVIHFAAHKAVEESIRN 159
Query: 107 PLEYYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGE--PEYLPINES----------- 153
PL+YY N+ G + + G+ V+SSS TVYG LP+ E
Sbjct: 160 PLKYYANNVGGLIDFATTLGEFGIKTFVFSSSATVYGTLATSGLPLKEELCVHKDEIFED 219
Query: 154 --------HPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIG 205
P +T+PYG++K+ CE I+ DL SD +W I++LRYFNPVG ESG +G
Sbjct: 220 RDGSKKLMEPGCTGITNPYGRTKWICEAILADLAASDPEWTIVALRYFNPVGCDESGLLG 279
Query: 206 EDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLF 265
EDP IP NL+P + +V G+ KEL++FG D+ T DGT VRD+IHV DLA GH+ A+
Sbjct: 280 EDPKQIPTNLLPVVVKVMTGQYKELQMFGTDWDTEDGTAVRDFIHVTDLARGHIAALSAA 339
Query: 266 HQPGF-NGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALAT 324
++ F NLGTGTG+SV+E+V + S GDV + VA +
Sbjct: 340 NEGKLKENFRTFNLGTGTGHSVMEVVNTMESVSSKAIPRRAADRRAGDVGSCVAVATRSQ 399
Query: 325 RSLGWRATRSLHDMC 339
L W+ ++L D C
Sbjct: 400 EELQWKTEKTLTDAC 414
>UniRef50_A2R0Z8 Cluster: Catalytic activity: UDPglucose =
UDPgalactose; n=1; Aspergillus niger|Rep: Catalytic
activity: UDPglucose = UDPgalactose - Aspergillus niger
Length = 407
Score = 229 bits (559), Expect = 1e-58
Identities = 139/364 (38%), Positives = 189/364 (51%), Gaps = 40/364 (10%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGG GY+GSHT + LL+ + +++VD+LSN++ RI L
Sbjct: 46 VLVTGGLGYIGSHTTLELLKAGYN-----VIIVDDLSNSF-------HHVFDRI--LLAA 91
Query: 65 TVHFYKVDIRCAEALDRIFENHN-IDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
HF + + D I ++ + I VIHFAA K V +S+ PL+YY N+ G L
Sbjct: 92 KQHFDRTVESSLDTSDSITQSRSRIVGVIHFAAFKDVNDSLRNPLKYYHNNVTGLVDLVS 151
Query: 124 IMRKHGVYKLVYSSSCTVYG----------------EPE-YLPINESHPTGKS-----LT 161
++ H + ++SSS VYG +PE Y ++ P +T
Sbjct: 152 LLADHDIKTFIFSSSANVYGTLAQNHGTLREEHCVHQPETYHSVSSGEPITSEQGCTGIT 211
Query: 162 SPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQ 221
+PYG++K+ E I+ D+ SD W II LRYFNP+G SG +GEDP G P+NL+P + Q
Sbjct: 212 NPYGRTKWIGEAILSDVAASDPSWTIIGLRYFNPIGCDPSGLLGEDPRGTPSNLVPVVVQ 271
Query: 222 VAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAI--KLFHQPGFNGFHAINLG 279
V G+L L V+G D+ T DGT +RD+IHV D+A GH A+ L Q N F NLG
Sbjct: 272 VLTGQLPALSVYGTDWETPDGTAIRDFIHVSDVARGHTAALAAALAGQVKTN-FRTFNLG 330
Query: 280 TGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMC 339
TG G+SV E+V+A S GDV VA A LGW A +SL D C
Sbjct: 331 TGRGHSVAEVVSAMEGVSHQSIPRRLAERRPGDVQECVAVPERAACELGWEAEKSLQDAC 390
Query: 340 RDTW 343
D W
Sbjct: 391 EDLW 394
>UniRef50_Q4WQU9 Cluster: UDP-glucose 4-epimerase; n=3;
Pezizomycotina|Rep: UDP-glucose 4-epimerase -
Aspergillus fumigatus (Sartorya fumigata)
Length = 415
Score = 225 bits (550), Expect = 1e-57
Identities = 135/372 (36%), Positives = 193/372 (51%), Gaps = 38/372 (10%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALK-RIEELTG 63
VLVTGG G++GSHT + LL+ + +++VD+LSN+Y + A K + G
Sbjct: 44 VLVTGGLGFIGSHTCLELLKAGYN-----VLIVDDLSNSYRHVFSRILLAAKLHCDRTDG 98
Query: 64 KT--VHFYKVDIRCAEALDRIFENHNIDC---------VIHFAALKAVGESVEKPLEYYQ 112
Y VD R A+ ++ + + D VIHFAA K V ES+ PL+YY+
Sbjct: 99 HCPKATLYDVDYRDTSAMRKLLDAYQRDPSTRQSRIIGVIHFAAFKQVEESIHTPLKYYR 158
Query: 113 VNINGTCTLFEIMRKHGVYKLVYSSSCTVYGE-PEYLPINES----------------HP 155
NING L ++ ++ + ++SSS VYG E+ P+ HP
Sbjct: 159 NNINGLVDLLVLLDQYRITTFIFSSSANVYGTLAEHRPLLHEDACTHQPDPGQRFGAFHP 218
Query: 156 T---GKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIP 212
+T+PYG++K F E I+ DL ++ W I++LRYFNP+G SG +GEDP P
Sbjct: 219 AEIHNSQITNPYGRTKLFGEAILADLARANPAWTIVALRYFNPIGCDASGLLGEDPKVHP 278
Query: 213 NNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGF-N 271
+NL+P + ++ GR EL ++G D+ T DGT VRD+IHV D+A GH A+ +
Sbjct: 279 SNLVPALVEILTGRRTELLIYGSDWETPDGTPVRDFIHVTDVARGHTAALAAARDGRVRD 338
Query: 272 GFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRA 331
GF NLGTG G+SVLE+V SG GD+ + VA A LGW
Sbjct: 339 GFRTFNLGTGRGHSVLELVQTLETVSGRTIPRRVVGRRAGDIGSCVASAERAAAELGWTT 398
Query: 332 TRSLHDMCRDTW 343
+SL + C D W
Sbjct: 399 AKSLTNACEDLW 410
>UniRef50_A0CJT6 Cluster: Chromosome undetermined scaffold_2, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_2,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 314
Score = 224 bits (547), Expect = 3e-57
Identities = 127/299 (42%), Positives = 185/299 (61%), Gaps = 23/299 (7%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+++LVTGG GY+GS T+ L + + G +I+++DNLSN+ + L I +
Sbjct: 2 QSILVTGGLGYIGSITITELYK--AIGKQYKIIILDNLSNSNI-------QVLDTITSII 52
Query: 63 GKTVHFYKVDIRCAEALDRIF----ENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGT 118
G+ + + VDI+ L+ +F E + I+ +IHFAALKAVGESVE P++YYQ N+ GT
Sbjct: 53 GEKLDLHIVDIQNYNELNEVFKKYKETNPINYIIHFAALKAVGESVENPIKYYQNNVVGT 112
Query: 119 CTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL 178
L +H ++SSS TVY E+ ++E P S +PYG++K E +++ L
Sbjct: 113 LNLLNCAEEHKCQNFLFSSSATVYAPGEF--VDEEAPFKPS--NPYGETKVVIEYLIRSL 168
Query: 179 CVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYP 238
S K + LRYFNPVGA + G++GE P+ PNNL PYI QVA+G L++L VFG+DY
Sbjct: 169 --SKKGGRYLCLRYFNPVGATKDGKLGEMPNK-PNNLFPYIEQVAIGNLQQLYVFGNDYN 225
Query: 239 TADGTGVRDYIHVCDLAAGHVQAIKLF---HQPGFNGFHAINLGTGTGYSVLEMVAAFS 294
T DGTG+RDYIH+ DLA HV A++ + N + N+GTG G+SVL++V +S
Sbjct: 226 THDGTGIRDYIHILDLAEAHVVALQELIKKDEKKENYYDYFNIGTGKGFSVLDIVNEYS 284
>UniRef50_Q1YMT2 Cluster: UDP-glucose 4-epimerase; n=3;
Alphaproteobacteria|Rep: UDP-glucose 4-epimerase -
Aurantimonas sp. SI85-9A1
Length = 341
Score = 218 bits (533), Expect = 2e-55
Identities = 133/345 (38%), Positives = 181/345 (52%), Gaps = 26/345 (7%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M++ VL+TGGAGY+G+HT + L ER E VV DNLSN + E
Sbjct: 7 MTKRVLITGGAGYIGAHTCLLLAERG-----YEAVVYDNLSNGHA--------------E 47
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+ F + DIR L +F + D +IHFA L V +SV PL +Y N++GT +
Sbjct: 48 FV-RWGAFEQGDIRDTNRLRSVFSQYQPDAIIHFAGLIEVAQSVRDPLAFYDNNVSGTLS 106
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L GV K+V+SS+C YG P++ P+ E H ++ SPYG SK E I++DL
Sbjct: 107 LITAAEAAGVDKIVFSSTCATYGIPQFTPLTEDHV--QAPISPYGWSKLLVEHILRDLSG 164
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
D+ I LRYFN GA RIGE + + +P + + A+G+ +FGDDY TA
Sbjct: 165 LDRIRCAI-LRYFNAAGADPEARIGEWHTP-ETHAVPLVIETALGQRDCFTIFGDDYDTA 222
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DGT +RDY+HV DLA HV+A++ G + A+NLGTGTG SV E+V + SG
Sbjct: 223 DGTCIRDYVHVIDLADAHVRAVEYLLNDGAS--VALNLGTGTGTSVAELVETVALVSGRP 280
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GD + +AD A LGW+ L WRW
Sbjct: 281 VKTRRADRRPGDPSILLADNRRARDVLGWQPQHDLASSIESAWRW 325
>UniRef50_A6C8E4 Cluster: UDP-glucose 4-epimerase; n=1; Planctomyces
maris DSM 8797|Rep: UDP-glucose 4-epimerase -
Planctomyces maris DSM 8797
Length = 345
Score = 218 bits (533), Expect = 2e-55
Identities = 128/350 (36%), Positives = 184/350 (52%), Gaps = 26/350 (7%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAGY+GSH V LL ++ V+DNLS + E
Sbjct: 3 ILVTGGAGYIGSHCVQQLLAAGQ-----KVCVIDNLSRGH--------------REAVPS 43
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F+++D+ + L + ++ I+ VIHFAAL VGESVE PL YY N GT +L +
Sbjct: 44 QASFFQLDLGETDELIDVMKSQRIEKVIHFAALAYVGESVENPLPYYANNTAGTLSLLQA 103
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
MR+ V ++V+SS+C YG PE +P+ E + ++ +PYG SK F E+I+ D S
Sbjct: 104 MRQSRVSQIVFSSTCATYGIPEQIPVTEE--SAQTPINPYGWSKLFIEQILTDCASSYPN 161
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+ I LRYFN G +G +GED S +L+P +G+ + + G+DYPTADGT
Sbjct: 162 FGFIGLRYFNVAGCAMNGSLGEDHSP-ETHLIPNCLNTVLGKQSHVTILGNDYPTADGTC 220
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
+RDYIHV D+ H+ A+ P N F+ N+G G+G+SVL++V +G
Sbjct: 221 IRDYIHVEDICRAHLLALNAL-TPQANRFY--NVGLGSGFSVLDVVKTTEQVTGREIPVE 277
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATR-SLHDMCRDTWRWQEANPNGY 353
GD A TR LGW SL ++ W W + +P+GY
Sbjct: 278 YQARRPGDPPMLSASHEKITRELGWSPRHTSLTEIIESAWNWFQKHPDGY 327
>UniRef50_Q9SGX0 Cluster: F1N19.2; n=1; Arabidopsis thaliana|Rep:
F1N19.2 - Arabidopsis thaliana (Mouse-ear cress)
Length = 447
Score = 217 bits (530), Expect = 4e-55
Identities = 104/176 (59%), Positives = 123/176 (69%), Gaps = 2/176 (1%)
Query: 71 VDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGV 130
VD+R AL+++F D V+HFA LKAVGESV KPL YY N+ T TL E+M HG
Sbjct: 125 VDLRDKPALEKVFSETKFDAVMHFAGLKAVGESVAKPLLYYNNNLIATITLLEVMAAHGC 184
Query: 131 YKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISL 190
KLV+SSS TVYG P+ +P E P S SPYG++K F E+I +D+ D +W II L
Sbjct: 185 KKLVFSSSATVYGWPKEVPCTEESPL--SGMSPYGRTKLFIEDICRDVQRGDPEWRIIML 242
Query: 191 RYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVR 246
RYFNPVGAH SGRIGEDP G PNNLMPY+ QV VGRL LK++G DY T DGTGVR
Sbjct: 243 RYFNPVGAHPSGRIGEDPCGTPNNLMPYVQQVVVGRLPNLKIYGTDYTTKDGTGVR 298
Score = 93.1 bits (221), Expect = 1e-17
Identities = 48/109 (44%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
VRDYIHV DLA GH+ A++ G NLGTG G +VLEMV AF ASG
Sbjct: 333 VRDYIHVVDLADGHICALQKLDDTEI-GCEVYNLGTGKGTTVLEMVDAFEKASGMKIPLV 391
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
GD A A R L W+A + +MCRD W W NP GY
Sbjct: 392 KVGRRPGDAETVYASTEKAERELNWKANFGIEEMCRDQWNWASNNPFGY 440
Score = 40.7 bits (91), Expect = 0.056
Identities = 21/39 (53%), Positives = 26/39 (66%), Gaps = 5/39 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNA 43
+LVTGGAGY+GSHTV+ LL VV+DNL N+
Sbjct: 5 ILVTGGAGYIGSHTVLQLLL-----GGYNTVVIDNLDNS 38
>UniRef50_P96995 Cluster: UDP-glucose 4-epimerase; n=51;
Bacteria|Rep: UDP-glucose 4-epimerase - Streptococcus
mutans
Length = 333
Score = 217 bits (530), Expect = 4e-55
Identities = 136/354 (38%), Positives = 188/354 (53%), Gaps = 30/354 (8%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
A+LV GGAGY+GSH V L+E+ + E+VVVD+L + A P A
Sbjct: 2 AILVLGGAGYIGSHMVDRLIEKGEE----EVVVVDSLVTGHRAAVH--PAA--------- 46
Query: 64 KTVHFYKVDIRCAEALDRIF-ENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
FY+ D+ E + +F EN ++D VIHFAA V ES++KPL+Y+ N G L
Sbjct: 47 ---KFYQGDLADREFMSMVFRENPDVDAVIHFAAYSLVAESMKKPLKYFDNNTAGMIKLL 103
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
E+M + GV +V+SS+ YG P+ +PI E+ P + +PYG+SK E IMK SD
Sbjct: 104 EVMSEFGVKYIVFSSTAATYGIPDEIPIKETTP--QRPINPYGESKLMMETIMK---WSD 158
Query: 183 KKWAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+ + I + LRYFN GA G IGED S +L+P I QVA G +++ +FGDDY T
Sbjct: 159 RAYGIKFVPLRYFNVAGAKPDGSIGEDHSP-ETHLLPIILQVAQGVREKIMIFGDDYNTP 217
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DGT VRDY+H DLA H+ A+ Q N A NLG+ TG+S L+++ A +G
Sbjct: 218 DGTNVRDYVHPFDLADAHLLALNYLRQG--NPSTAFNLGSSTGFSNLQILEAARKVTGQK 275
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQEANPNGY 353
GD +A A LGW+ + + W W + P GY
Sbjct: 276 IPAEKAARRSGDPDTLIASSEKAREVLGWKPQFDDIEKIIASAWAWHSSYPKGY 329
>UniRef50_A6LLZ0 Cluster: UDP-glucose 4-epimerase; n=2;
Bacteria|Rep: UDP-glucose 4-epimerase - Thermosipho
melanesiensis BI429
Length = 321
Score = 217 bits (529), Expect = 5e-55
Identities = 130/344 (37%), Positives = 182/344 (52%), Gaps = 30/344 (8%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
A+LV GGAGY+GSH L S G +++V DNLS+ Y E K E + G
Sbjct: 2 AILVAGGAGYIGSHVCKML---HSKG--YKVIVYDNLSHGY-------KEFAKWGEFIPG 49
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
DI E LD IF++++ID V+HF A VGESV P +YY+ N+ T L +
Sbjct: 50 --------DISDVELLDNIFKHYHIDAVMHFCAYIEVGESVVDPQKYYENNVGNTIKLLK 101
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+MRK+ + K ++SS+ VYG PE +PI E K +PYGKSK+ E++++D DK
Sbjct: 102 VMRKNNIDKFIFSSTAAVYGMPEKVPIKEDDK--KDPINPYGKSKWMVEQMLEDY---DK 156
Query: 184 KWAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ + I RYFN GA E G IGE +L+P I A+GR +K+FG +Y T D
Sbjct: 157 AYGLKSIRFRYFNAAGADEEGEIGEAHKP-ETHLIPLILDAAIGRRDSIKIFGTNYDTKD 215
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GT +RD++HV DLA H++ ++ G + NLG+G GYSV E++ A +
Sbjct: 216 GTCIRDFVHVNDLADAHIKGLEYLLDGGKTDY--FNLGSGEGYSVYEVIEAVKRVTKKNF 273
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GD +AD A LGW SL ++ W W
Sbjct: 274 KVVETDRRPGDPAYLIADSTKAKEKLGWEVKYSLDEIILTAWNW 317
>UniRef50_Q9ABX8 Cluster: UDP-glucose 4-epimerase; n=1; Caulobacter
vibrioides|Rep: UDP-glucose 4-epimerase - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 327
Score = 215 bits (526), Expect = 1e-54
Identities = 136/347 (39%), Positives = 182/347 (52%), Gaps = 34/347 (9%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+ VLVTGGAGYVGSH + L E VV D+LSN + + P +
Sbjct: 2 QTVLVTGGAGYVGSHCCLALAEAG-----FRPVVFDDLSNGHREHVQWGPLEVG------ 50
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
DIR A LD +F + V+HFAA VGESV+ P ++ N+ GT TL
Sbjct: 51 ---------DIRDAARLDAVFAAYAPVAVLHFAARIEVGESVKNPGAFFDTNVGGTITLI 101
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
E R+ GV +V+SS+C +G+P LP+ E+HP ++ +PYG+SK E+ + D D
Sbjct: 102 EAARRAGVKVVVFSSTCATFGDPVDLPMKETHP--QAPLNPYGRSKLMVEQALADY---D 156
Query: 183 KKWAIIS--LRYFNPVGAHESGRIGE--DPSGIPNNLMPYISQVAVGRLKELKVFGDDYP 238
+ + S +RYFN GA GRIGE +P + +P QVA+G+ +FGDDY
Sbjct: 157 RYVGLKSAVMRYFNAAGADPQGRIGEWHEPE---THAVPLAIQVALGQRPRFTIFGDDYD 213
Query: 239 TADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
T DGT VRDY+HV DLA HV A+K G + NLGTGTG +V E+V +G
Sbjct: 214 TRDGTAVRDYVHVLDLADAHVAALKRLLVGGSS--ETYNLGTGTGTTVRELVDGVGKVAG 271
Query: 299 XXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GD V D A A LGW+A+RSL ++ WRW
Sbjct: 272 APLPVEIASRRPGDAPVLVGDHAKARAELGWKASRSLDEILSTAWRW 318
>UniRef50_Q0U254 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 477
Score = 215 bits (526), Expect = 1e-54
Identities = 120/283 (42%), Positives = 155/283 (54%), Gaps = 22/283 (7%)
Query: 88 IDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEY 147
I VIHFAA K+V ES+ PL YY N+ G ++ + G+ LV+SSS TVYGE
Sbjct: 182 ISGVIHFAAYKSVEESIRMPLRYYSNNVCGLVDFLALLEQFGIKNLVFSSSATVYGEGAN 241
Query: 148 --LPINES----HPTG---------------KSLTSPYGKSKYFCEEIMKDLCVSDKKWA 186
+P+ E HP LTSPYG+SK+ CE I+ D+ SD W+
Sbjct: 242 CGVPLREELCVHHPESFVDSDGSERQVIPGVMGLTSPYGRSKFMCESILADVARSDPSWS 301
Query: 187 IISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVR 246
I +LRYFNPVG HESG +GEDP P+NL+P I+ V G L +FG D+ T DGT VR
Sbjct: 302 ITALRYFNPVGCHESGILGEDPRQKPSNLIPVIATVLTGTRPVLDIFGTDWNTPDGTAVR 361
Query: 247 DYIHVCDLAAGHVQAIKLFHQPGF-NGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXX 305
D+IHV DLA GH+ A+ F NLGTG G++V E++++ AS
Sbjct: 362 DFIHVVDLARGHIAALAASAAGRIKTAFRTYNLGTGRGHTVREVLSSLEQASRRTIPARE 421
Query: 306 XXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEA 348
GDV VA+V A L WRATR+L D D W + +A
Sbjct: 422 VGRRAGDVGFCVAEVRRAEEELQWRATRTLDDCSGDVWNFTKA 464
Score = 45.6 bits (103), Expect = 0.002
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 8/76 (10%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAY-CAEGEKKPEALK--RI 58
SR ++V GG GY+GSHT + LL+ + +VVVD+LSN+Y G + A+ +
Sbjct: 55 SRFIMVVGGLGYIGSHTTLELLK-----EGYNVVVVDDLSNSYEDVLGRIRALAMAHCKA 109
Query: 59 EELTGKTVHFYKVDIR 74
E T+HF ++D R
Sbjct: 110 EGKQMPTLHFRQLDYR 125
>UniRef50_Q9SA77 Cluster: UDP-arabinose 4-epimerase 1; n=31;
Viridiplantae|Rep: UDP-arabinose 4-epimerase 1 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 419
Score = 213 bits (521), Expect = 4e-54
Identities = 132/355 (37%), Positives = 189/355 (53%), Gaps = 24/355 (6%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGGAGY+GSH + LL+ + + +VDNLS A A++ ++EL +
Sbjct: 73 VLVTGGAGYIGSHAALRLLK-----ESYRVTIVDNLSRGNLA-------AVRILQELFPE 120
Query: 65 T--VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
+ F D+ A+A+++IF + D V+HFAA+ VGES + PL+YY + T +
Sbjct: 121 PGRLQFIYADLGDAKAVNKIFTENAFDAVMHFAAVAYVGESTQFPLKYYHNITSNTLVVL 180
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
E M HGV L+YSS+C YGEP+ +PI E P + +PYGK+K E+I+ D +
Sbjct: 181 ETMAAHGVKTLIYSSTCATYGEPDIMPITEETP--QVPINPYGKAKKMAEDIILDFS-KN 237
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPS---GIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
A++ LRYFN +G+ GR+GE P + A G + L++ G DY T
Sbjct: 238 SDMAVMILRYFNVIGSDPEGRLGEAPRPELREHGRISGACFDAARGIMPGLQIKGTDYKT 297
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
ADGT VRDYI V DL HV+A++ +P G + N+GTG G SV E V A A+G
Sbjct: 298 ADGTCVRDYIDVTDLVDAHVKALQK-AKPRKVGIY--NVGTGKGSSVKEFVEACKKATGV 354
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATR-SLHDMCRDTWRWQEANPNGY 353
GD +D + + L W A +L + WRWQ+ + NGY
Sbjct: 355 EIKIDYLPRRAGDYAEVYSDPSKIRKELNWTAKHTNLKESLETAWRWQKLHRNGY 409
>UniRef50_Q5KUQ5 Cluster: UDP-glucose 4-epimerase; n=5;
Bacteria|Rep: UDP-glucose 4-epimerase - Geobacillus
kaustophilus
Length = 323
Score = 213 bits (520), Expect = 6e-54
Identities = 129/345 (37%), Positives = 173/345 (50%), Gaps = 25/345 (7%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LV GGAGY+GSH V L+E++ +++V+DNLS + L
Sbjct: 2 ILVVGGAGYIGSHLVKELVEKE------QVIVLDNLSTGH--------------RYLVDD 41
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F + D+ L+ IF + I V+HFAA VGESV PL+YYQ N+ T TL E
Sbjct: 42 RAVFVQGDLGNKADLEPIFGKYPIQAVMHFAANSLVGESVVNPLKYYQNNVAATLTLLET 101
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
M K+ V ++SS+ YG P I E PT +PYG+SK E+I+ D S
Sbjct: 102 MLKYNVKNFIFSSTAATYGIPNVELITEDCPTNP--INPYGRSKLMIEQILADF-ASAYG 158
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+ LRYFN GAHESG IGED + +L+P + Q +G+ ++ VFG DY T DGT
Sbjct: 159 LNYVVLRYFNAAGAHESGEIGEDHNP-ETHLIPLVLQHLLGQRDKISVFGTDYDTPDGTC 217
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
+RDYIHV DLA H+ A++ G NLG G GYSV E++ +G
Sbjct: 218 IRDYIHVTDLAKAHILALEAL-LSGKKKTAVYNLGNGLGYSVKEVIETCEKVTGRKAVIE 276
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
GD VA LGW+A SL + W+W N
Sbjct: 277 YTDRRPGDPARLVASSQKIYEELGWKAEYSLEQIIESAWKWHSRN 321
>UniRef50_Q8YN57 Cluster: UDP-glucose 4-epimerase; n=43;
Bacteria|Rep: UDP-glucose 4-epimerase - Anabaena sp.
(strain PCC 7120)
Length = 332
Score = 213 bits (519), Expect = 8e-54
Identities = 126/345 (36%), Positives = 186/345 (53%), Gaps = 24/345 (6%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
++LVTGGAGY+GSHTV+ L + D +V++DNL + EK + ++E + G
Sbjct: 7 SILVTGGAGYIGSHTVLALKQAGYD-----VVILDNLVYGHRDLVEK----VLQVELVVG 57
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
T LD +F++ + D V+HF+A VGESV P +YY+ N+ GT TL E
Sbjct: 58 DTGD--------RPLLDELFKSRHFDAVMHFSAYAYVGESVSDPAKYYRNNVLGTLTLLE 109
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
M + K V+SS+C YG P+ +PI E HP ++ +PYG +K E I+ D V+
Sbjct: 110 AMLAASINKFVFSSTCATYGVPKTVPIPEDHP--QNPINPYGATKLMVERILADFDVA-Y 166
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
+ RYFN GA+ G +GED + +L+P + A+G+ K + +FG DYPT DGT
Sbjct: 167 GLKSVRFRYFNAAGANPDGLLGEDHNP-ETHLIPLVLLTALGKRKFISIFGTDYPTPDGT 225
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
+RDYIHV DLA HV +K + G + NLG G G+SV E++AA +G
Sbjct: 226 CIRDYIHVNDLADAHVLGLKYLLKGGDS--EVFNLGNGQGFSVREVIAAGEQVTGLPITV 283
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQE 347
GD + + A + LGW+ S+ D+ W+W +
Sbjct: 284 EECDRRPGDPPSLIGSGEKARKILGWQPQYSSIKDIVSHAWQWHQ 328
>UniRef50_A0Z893 Cluster: UDP-glucose 4-epimerase; n=1; marine gamma
proteobacterium HTCC2080|Rep: UDP-glucose 4-epimerase -
marine gamma proteobacterium HTCC2080
Length = 329
Score = 211 bits (516), Expect = 2e-53
Identities = 134/353 (37%), Positives = 183/353 (51%), Gaps = 30/353 (8%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
MS LVTGGAGY+GSH V+ L+E + + V+D+ S + E
Sbjct: 1 MSLHYLVTGGAGYIGSHLVLALVEAEH-----RVTVLDDFSTGHRWATE----------- 44
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
G V +VDIR AL + + D V HFAA VGES +KPL YYQ N++GT
Sbjct: 45 --GHEV--IEVDIRDLAALRSALLHRHFDGVFHFAAKSLVGESGQKPLLYYQNNVSGTAN 100
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L E+ + G V+SS+ VYG P+ I E HP + YG++K E+++ +
Sbjct: 101 LLEVALESGWGHCVFSSTAAVYGSPQARVIAEEHPLNP--VNVYGETKLAMEQMLSAVHK 158
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGE--DPSGIPNNLMPYISQVAVGRLKELKVFGDDYP 238
A + LRYFN GA GE +P +L+P I + A G + L +FGDDY
Sbjct: 159 QGAMQA-VCLRYFNAAGAAPDAHRGEWHEPE---THLIPNILRKAAGEDRALTIFGDDYD 214
Query: 239 TADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
T DGT +RDYIHV DLA H++A+ + H+ G GFH +NLG+ GYSV E++ A G
Sbjct: 215 TPDGTCIRDYIHVLDLAQAHLKAMTMLHREG--GFHTLNLGSEAGYSVREILEACETTVG 272
Query: 299 XXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPN 351
GD VAD + A + L WRATRSL ++ W W++ N
Sbjct: 273 RPITHEIGPRRRGDPARLVADASRAGQILDWRATRSLGEIVESAWLWEQERQN 325
>UniRef50_Q8RGC6 Cluster: UDP-glucose 4-epimerase; n=2;
Fusobacterium nucleatum|Rep: UDP-glucose 4-epimerase -
Fusobacterium nucleatum subsp. nucleatum
Length = 324
Score = 204 bits (498), Expect = 3e-51
Identities = 124/330 (37%), Positives = 173/330 (52%), Gaps = 27/330 (8%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+ +LVTGGAGY+GSH V+ LL+ + +VV+D L N + +E
Sbjct: 2 QTILVTGGAGYIGSHAVVELLDNNYN-----VVVIDTLENGF--------------KEFV 42
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
K FY+ +++ E + RIF+ + I+ V+HFA V ESV+ P +YY N T L
Sbjct: 43 DKRAKFYQGNVQDYELMSRIFQENKIEAVMHFAGYIRVPESVDDPNKYYLNNTYTTMCLI 102
Query: 123 EIMRKHGVYKLVYSSSCTVYGE-PEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
+ M KH + +++SS+ VYGE E PI+E H T +PYG SK E I++D C
Sbjct: 103 QSMVKHNIKNIIFSSTAAVYGEITEDNPIDEKHST--IPINPYGASKLMSERIIRD-CAK 159
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
RYFN GAHE IG+ +G+ +L+ Q A + L+VFGDD+PT D
Sbjct: 160 AYGLNYSIFRYFNVAGAHEKYPIGQKGAGV-TSLITLTLQAAKDSNRILEVFGDDFPTKD 218
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GTG+RDYIHV DL HV ++KL + N + NLG G G+SVLE V A +
Sbjct: 219 GTGIRDYIHVVDLVKAHVLSLKLLFK---NESNIFNLGNGNGFSVLETVEAARKVTNKEI 275
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRA 331
GD +A A + LGW+A
Sbjct: 276 ICKIAARRKGDPACVIASSEKAKKILGWKA 305
>UniRef50_Q5FQW6 Cluster: UDP-glucose 4-epimerase; n=3;
Bacteria|Rep: UDP-glucose 4-epimerase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 328
Score = 201 bits (490), Expect = 3e-50
Identities = 135/353 (38%), Positives = 182/353 (51%), Gaps = 35/353 (9%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTGGAG+VGSH V+ LL+ D +VV+DNLS Y E P+
Sbjct: 4 LVTGGAGFVGSHAVLALLDAGHD-----VVVLDNLSTGY---REAVPDG----------- 44
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
V F+KVD+ A + D V+HFAAL VG+S+ P Y + N L +I
Sbjct: 45 VPFHKVDLLDYAATSAVVAQGKWDGVLHFAALSLVGDSMRDPFHYLRQNYLTALNLVQIC 104
Query: 126 RKHGVYKLVYSSSCTVYGEPEYL-PINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+HGV K+V+SS+ ++G PE L PI E+ P SPYG+SK+ E + L +D
Sbjct: 105 VEHGVKKIVFSSTAALFGGPERLDPIPETAPVQPG--SPYGESKFMIERV---LHWADAI 159
Query: 185 WAIIS--LRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ + S LRYFN GA GR GED +L+P A+GR LK+FG DYPT DG
Sbjct: 160 YGLRSACLRYFNAAGADPQGRAGEDHRP-ETHLIPLTIDAALGRRPALKLFGTDYPTRDG 218
Query: 243 TGVRDYIHVCDLAAGHVQAI-KLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
+ VRDYIHV DLA HV+A+ ++ H+ N+G G GYS LE++ + SG
Sbjct: 219 SCVRDYIHVTDLADAHVRALGQIDHRS-----VTYNIGNGQGYSNLEVIQSVERVSGRKV 273
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQEANPNGY 353
GD VAD GW ++ + RW+E++PNGY
Sbjct: 274 PWEAAPRREGDPALLVADSTTLRNDTGWTPRFGNIDSIVETALRWRESHPNGY 326
>UniRef50_A5AK58 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 477
Score = 198 bits (482), Expect = 2e-49
Identities = 113/233 (48%), Positives = 136/233 (58%), Gaps = 25/233 (10%)
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINES------HPTG--KSLTSPYGKS------- 167
E+ RK +V+SSS TVYG+P+ +P E +P G KS +P +
Sbjct: 56 ELSRKLHFNLMVFSSSATVYGQPDKIPCVEDFNLMAMNPYGRTKSGQTPLRQCQCSLIPC 115
Query: 168 ----------KYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP 217
K F EEI +D+ ++ W II LRYFNPVGAHESG++GEDP GIPNNLMP
Sbjct: 116 LPKYSLIPWLKLFLEEIARDIQKAEPDWKIILLRYFNPVGAHESGKLGEDPKGIPNNLMP 175
Query: 218 YISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAIN 277
YI QVAVGRL EL V+G DYPT DG+ +RDYIHV DLA GH+ A++ G A N
Sbjct: 176 YIQQVAVGRLPELNVYGHDYPTRDGSAIRDYIHVMDLADGHIAALRKLFTSEDIGCTAYN 235
Query: 278 LGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWR 330
LGTG G SVLEMVAAF ASG GD TA A A + LGW+
Sbjct: 236 LGTGQGTSVLEMVAAFEKASGKKIPIKLCPRRAGDATAVYASTEKAAKELGWK 288
Score = 45.2 bits (102), Expect = 0.003
Identities = 25/61 (40%), Positives = 39/61 (63%), Gaps = 12/61 (19%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R +LVTGGAG++G+HTV+ LL S+G + ++DNL N+ EA++R+ +L
Sbjct: 6 RTILVTGGAGFIGTHTVVQLL---SEG--FTVWIIDNLDNSVL-------EAIERVRDLV 53
Query: 63 G 63
G
Sbjct: 54 G 54
>UniRef50_UPI0000383ECD Cluster: COG1087: UDP-glucose 4-epimerase;
n=1; Magnetospirillum magnetotacticum MS-1|Rep: COG1087:
UDP-glucose 4-epimerase - Magnetospirillum
magnetotacticum MS-1
Length = 326
Score = 194 bits (474), Expect = 2e-48
Identities = 124/347 (35%), Positives = 176/347 (50%), Gaps = 30/347 (8%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAGYVGSHT+ L+ ++ P I+VVDNL G + +
Sbjct: 2 LLVTGGAGYVGSHTLHHLI--RNGYSPESIIVVDNL-----CRGSR---------DAVPH 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
VHF +VD+ E L +F H++ VIHFA V ES+ P YY+ N+ +L E
Sbjct: 46 GVHFAEVDLLDTEVLVELFRRHDVSAVIHFAGFAYVDESMADPTAYYRTNVVAGLSLLEA 105
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMK--DLCVSD 182
M + G +V+SS+C YG P +PI ES P + +PYG++K E ++ + C
Sbjct: 106 MVRVGCRAIVFSSTCATYGTPSSVPIAESEP--QIPINPYGETKLVFERALEWYERCHGI 163
Query: 183 KKWAIISLRYFNPVG-AHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ + LRYFN G A+ G G ++P A+GR +K+FG DY T+D
Sbjct: 164 RH---VILRYFNAAGAAYGVGSYGNHDV----RMIPAAVLAAMGRRPPVKIFGTDYETSD 216
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GT VRDY+HV DLA GH A++ + G + A+NLG+G G SVL ++ A G
Sbjct: 217 GTCVRDYVHVADLAEGHCLALEHLREDGAS--TALNLGSGRGSSVLNILEAVHRIGGRPV 274
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEA 348
D +AD LA R LGW +L D+ W W ++
Sbjct: 275 PNEKSPRRLCDPPTLIADTRLAQRILGWHPAYTLDDIISSVWHWHQS 321
>UniRef50_Q59083 Cluster: UDP-glucose 4-epimerase; n=14;
Bacteria|Rep: UDP-glucose 4-epimerase - Azospirillum
brasilense
Length = 348
Score = 192 bits (469), Expect = 9e-48
Identities = 130/348 (37%), Positives = 172/348 (49%), Gaps = 26/348 (7%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL 61
S VLVTGGAGY+GSH + L + G P V +D+LS E P A+ +E
Sbjct: 8 SPRVLVTGGAGYIGSHVLHALTDA---GIPA--VTIDDLS---AGRREAIPAAVPLVEG- 58
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
DI AE LDR+ +H +D V+HFA V ESV KPL+YY+ N + TL
Sbjct: 59 ----------DIGSAELLDRVMRDHRVDAVMHFAGSIVVPESVVKPLDYYRNNTANSLTL 108
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
+ G+ K+V+SS+ VYG PE +PI E PT +PYG SK E++++D +
Sbjct: 109 LGACLRAGIDKVVFSSTAAVYGAPESVPIREDAPTVP--INPYGASKLMTEQMLRDAGAA 166
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
++I LRYFN GA +GR G+ + + +L+ Q +GR L +FG DY T D
Sbjct: 167 HGLRSVI-LRYFNVAGADPAGRTGQ-ATPVATHLIKVACQALLGRRPPLAIFGTDYDTPD 224
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GT +RDYIHV DLA HV A L H G +N G G G SV E+V SG
Sbjct: 225 GTCIRDYIHVSDLADAHVLA--LLHLRRGGGSLLMNCGYGRGASVREVVRTLEEVSGEQV 282
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRS-LHDMCRDTWRWQEA 348
GD VA LGW L + R W+ +
Sbjct: 283 PATFADRRPGDPPQLVAGADRIREQLGWVPKHDRLDGIVRSALSWERS 330
>UniRef50_A3ERM8 Cluster: UDP-glucose 4-epimerase; n=1;
Leptospirillum sp. Group II UBA|Rep: UDP-glucose
4-epimerase - Leptospirillum sp. Group II UBA
Length = 323
Score = 190 bits (463), Expect = 5e-47
Identities = 124/331 (37%), Positives = 173/331 (52%), Gaps = 26/331 (7%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
++VTGGAGY+GSH V L+E + E V++DNLS+ K + TG
Sbjct: 2 IIVTGGAGYIGSHMVRVLIE-----NGFETVILDNLSH-----------GTKEVAVQTGA 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ DIR AL +F ++ I+ VIHFAA VGESV+ PL+Y+ N+NGT + E
Sbjct: 46 PL--VVGDIRDPRALTSLFSHYPIEAVIHFAAAIEVGESVQDPLKYWDNNLNGTLRILET 103
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
MR GV L+ SS+ VY PI E +PYG++K E ++ + C
Sbjct: 104 MRSFGVRNLILSSTAAVYSPKSDGPITEEDRIDPQ--NPYGETKAAAERLV-EACRHAFG 160
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIP-NNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
+ + RYFN S G IP ++L+P + GR+ L+VFG+DYPT DGT
Sbjct: 161 VSSVIFRYFNAAALEPS--YGLVSHAIPRSHLIPAVLDAISGRIPALRVFGNDYPTPDGT 218
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
GVRDYIHV DLA H+ A+K + +G NLGTG G+SVL+++ +G
Sbjct: 219 GVRDYIHVMDLAEAHLVALKRLLKGEISG--TFNLGTGQGHSVLDVIRTAEKVTGKKVPY 276
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRS 334
GDV+ VA A ++L W +RS
Sbjct: 277 RIEARRPGDVSMLVASGTRARQTLPWFPSRS 307
>UniRef50_Q6KI97 Cluster: Udp-glucose 4-epimerase; n=1; Mycoplasma
mobile|Rep: Udp-glucose 4-epimerase - Mycoplasma mobile
Length = 330
Score = 187 bits (456), Expect = 3e-46
Identities = 126/346 (36%), Positives = 180/346 (52%), Gaps = 29/346 (8%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LV GGAGY+GSHTV L+E + ++V++DNL+ + PEA
Sbjct: 4 LVIGGAGYIGSHTVYELIENNN-----KVVILDNLTTG--SNSSIHPEA----------- 45
Query: 66 VHFYKVDIRCAEALDRIF-ENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
FY+ D + + L++IF EN I+ VI+FAA V ESV +PL+YY N G L E
Sbjct: 46 -KFYEGDFKDKKILNKIFDENKEIEIVINFAASIVVSESVYEPLKYYLNNTYGVMILLES 104
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC-VSDK 183
M+++ L++SS+ VYG+ LPI E +PYG SK E+I++D V+D
Sbjct: 105 MKENNKKFLIFSSTAAVYGQKSNLPIREDEDLNP--INPYGSSKQMSEKIIQDYAHVNDF 162
Query: 184 KWAIISLRYFNPVGAHESGRIGEDP--SGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
K+AI LRYFN GAH++ IG P ++L+P IS L LK+FG++Y T D
Sbjct: 163 KFAI--LRYFNVAGAHQNNSIGLVPKKGHKVSHLIPSISSFVFNELDSLKIFGNNYDTKD 220
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GT +RDYIHV DLA H A K + N +N+G+ G+SVLE+V F
Sbjct: 221 GTCIRDYIHVQDLAHAHFLAAKYIFENKTN--LIVNVGSEKGFSVLEVVKTFEKQLNKKL 278
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQE 347
GD VA + L ++ SL ++ + W++
Sbjct: 279 NYEINPKRDGDPAFLVASTTKIAKILNFKPKFSLEEIVKTELAWRK 324
>UniRef50_Q6MS04 Cluster: UDP-glucose 4-epimerase; n=3; Mycoplasma
mycoides subsp. mycoides SC|Rep: UDP-glucose 4-epimerase
- Mycoplasma mycoides subsp. mycoides SC
Length = 334
Score = 185 bits (451), Expect = 1e-45
Identities = 115/346 (33%), Positives = 176/346 (50%), Gaps = 22/346 (6%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
L+ GGAGY+GSH V ++ + D ++++ DNLS+ + + +
Sbjct: 4 LLIGGAGYIGSH-VAEIINKT---DNNKVIIYDNLSSG--------------LNDFIEQK 45
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
F + DI L+ +F ++ ID VI+ A L VGESV+KPL+YYQ NI G +IM
Sbjct: 46 STFIQGDILDFNKLNEVFSSNKIDVVIYLAGLIKVGESVQKPLDYYQTNILGLINTLKIM 105
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
+ H V V+SSS VYG K SPYG++KYF EEI+KD +++ +
Sbjct: 106 QAHNVNYFVFSSSAAVYGNNSRHNGYFYEDDPKEPCSPYGRTKYFGEEIIKDFAIANPNF 165
Query: 186 AIISLRYFNPVGAHESGRIG--EDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
LRYFN GA +S RIG + P +L+P IS A G + +FG DY T DGT
Sbjct: 166 HYTFLRYFNVAGASKSKRIGYLTKDNNKPTHLIPAISYFAFGLTDQFSIFGSDYNTKDGT 225
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
+RDY++VC+LA H+ + + N ++ N+G+G G+S LE++ F G
Sbjct: 226 CIRDYVYVCELAELHLLTAQKMVKENCNLYY--NIGSGKGFSNLEIIKKFEKQLGYKLNI 283
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
GD VA + L ++ ++ D+ +++A+
Sbjct: 284 DIAPKRSGDPDVLVASNTKLCQELNYKIKTNIKDIVESEIAFRKAH 329
>UniRef50_Q1QJ29 Cluster: UDP-glucose 4-epimerase; n=1; Nitrobacter
hamburgensis X14|Rep: UDP-glucose 4-epimerase -
Nitrobacter hamburgensis (strain X14 / DSM 10229)
Length = 349
Score = 185 bits (450), Expect = 2e-45
Identities = 130/345 (37%), Positives = 173/345 (50%), Gaps = 36/345 (10%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
AVLVTGGAGY+GSH L E V DN S G ++ +K +TG
Sbjct: 6 AVLVTGGAGYIGSHCCKALAEAG-----YRPVCFDNFST-----GHRR--FVKWGPMITG 53
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
D+R L +F++++ V+HFAA +VGESV P +YY N+ GT L
Sbjct: 54 --------DVRDPRQLQAVFQSYDFSAVMHFAASSSVGESVTDPQKYYANNVGGTLALLS 105
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
MR G +LV+SS+ VYG +ES P + +PYGKSK EEI+ D +
Sbjct: 106 AMRGAGSGRLVFSSTGAVYGNAG----SESAP--RFPVNPYGKSKLMIEEILSDYRQA-Y 158
Query: 184 KWAIISLRYFNPVGAHESGRIGE--DPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ RYFN GA G IGE DP +L+P G + + +FGDDY T D
Sbjct: 159 DLNSVCFRYFNASGADACGAIGECRDPE---THLIPRAMMALQGEIPDFGIFGDDYDTPD 215
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GT VRDYIHV DL + HVQA+ + G G + NLGTG GYSV E+++A +G
Sbjct: 216 GTAVRDYIHVTDLVSAHVQAVNML-MGGMRGVY--NLGTGVGYSVSEVLSAIFAEAGSKM 272
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRS-LHDMCRDTWRW 345
GD + +AD ++A LG+ S L + R W W
Sbjct: 273 PRVYYPRRPGDPSVLIADSSVARMHLGFNPIHSNLGTIIRTAWNW 317
>UniRef50_A0LVI8 Cluster: UDP-glucose 4-epimerase; n=6;
Actinomycetales|Rep: UDP-glucose 4-epimerase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 329
Score = 184 bits (448), Expect = 3e-45
Identities = 132/344 (38%), Positives = 176/344 (51%), Gaps = 33/344 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGGAGY+GS L+E DG ++VV+D+LS + +
Sbjct: 3 VLVTGGAGYIGSVVTRVLIE---DGH--DVVVLDDLSTGH--------------RDAVPA 43
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V F DI A+A D + D V+HFAA VGES+ +P Y+ N+ GT L +
Sbjct: 44 GVPFVHADI--ADAGD-VLAREPFDGVLHFAAKSLVGESMNRPELYWATNVCGTRHLLDA 100
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
MR+H V +L++SS+ VYGE I E P TSPYG SK + ++ D C +
Sbjct: 101 MRRHSVPRLIFSSTAAVYGEGGPDGIGEDTPPRP--TSPYGTSKLAVDLMISDECRAYPL 158
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
A +SLRYFN GA+ G GE +L+P VA GR L+++G+D+PT DGT
Sbjct: 159 GA-VSLRYFNVAGAY--GPCGE-RHRTETHLIPITLDVAAGRRPHLEIYGNDWPTPDGTC 214
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAI-NLGTGTGYSVLEMVAAFSNASGXXXXX 303
+RDYIHV DLA HV A+ Q G HAI NLG G G+SV E+VAA +G
Sbjct: 215 MRDYIHVLDLARAHVVAL----QHARPGHHAIYNLGNGRGFSVREVVAAVERVTGRRVPV 270
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQE 347
GD VAD + A L W+ L + D W + +
Sbjct: 271 TVAPRRPGDPAWLVADDSRARAELNWQPQADLDTIIADAWAFHQ 314
>UniRef50_UPI000023E28B Cluster: hypothetical protein FG07983.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG07983.1 - Gibberella zeae PH-1
Length = 885
Score = 183 bits (445), Expect = 7e-45
Identities = 125/366 (34%), Positives = 182/366 (49%), Gaps = 57/366 (15%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLS----NAYCAEGEKKPEALKRIEE 60
+LVTGG G++GSHT + LL+ + +++VD+L + + + + +A++ + E
Sbjct: 50 ILVTGGLGFIGSHTSLELLKAGYN-----VIIVDDLRLKLPTLHFHKLDYRSKAMRFLLE 104
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+ + + + + I I VIHFAA K+V ES+EKP++YY+ N+ G
Sbjct: 105 SYSTLIPTFSEN-----SGEFIKIQSKISGVIHFAAFKSVSESIEKPVQYYRNNVCGLID 159
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEP---------------EYLPINE------SHPTGKS 159
E++ KH ++K V+SS TVY E L ++E + +
Sbjct: 160 FIELLGKHNIHKFVFSSLATVYRSKAVKGKHLREEEVVYHETLYLDEFNNETLAELSVSE 219
Query: 160 LTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYI 219
LTSPY SKYFCE ++ D+ +D W II+LRYFNP+G SG +GEDP GIP NL P I
Sbjct: 220 LTSPYRCSKYFCEAVLADIAYTDPSWHIIALRYFNPIGCDPSGPLGEDPKGIPTNLFPVI 279
Query: 220 SQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLG 279
+QV T +RD+IHV DLA GHV A+ + F F NLG
Sbjct: 280 AQVL-------------------TAIRDFIHVTDLARGHVAALSSDIESPFRTF---NLG 317
Query: 280 TGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMC 339
TG G +V E V + AS GDV VA A + LGW A ++
Sbjct: 318 TGNGTTVAEAVKSLEGASLKNIAVNLVPRRIGDVGFCVAANDRAKKELGWTAKETIQQFA 377
Query: 340 RDTWRW 345
+D W +
Sbjct: 378 KDLWNY 383
>UniRef50_Q604T5 Cluster: UDP-glucose 4-epimerase; n=26;
Proteobacteria|Rep: UDP-glucose 4-epimerase -
Methylococcus capsulatus
Length = 341
Score = 182 bits (444), Expect = 1e-44
Identities = 125/327 (38%), Positives = 166/327 (50%), Gaps = 26/327 (7%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+ +LVTGGAGY+GSH V TL E G+ L VV+DNLS + R L
Sbjct: 4 KGILVTGGAGYIGSHVVKTLGEA---GERL--VVLDNLSTGF------------RDAVLY 46
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
G F + D LD+I ++ ++ V+HFAA V ESVE PL+YY N T TL
Sbjct: 47 GD---FIEGDTGDDVLLDKIMRDYEVEAVMHFAAHTIVPESVENPLKYYGNNTCKTRTLL 103
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
E RK GV ++SS+ VYG PE E+ P +PYG SK E +++DL +
Sbjct: 104 ESCRKAGVSHFIFSSTAAVYGIPEGEFALETSPLAP--INPYGSSKLMSEIMLRDLSTAS 161
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
++ LRYFN G+ GRIG+ + L+ ++VA G+ L +FG DYPT DG
Sbjct: 162 PLRHVV-LRYFNVAGSDPEGRIGQS-TAKATLLIKVAAEVATGKRDRLCIFGTDYPTPDG 219
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
TG+RDYIHV DLA HV A+ G + +N G G GYSV E++ + +G
Sbjct: 220 TGIRDYIHVSDLADAHVAALAYLRAGGES--RTLNCGYGHGYSVREIIDTMNRVNGTPIA 277
Query: 303 XXXXXXXXGDVTANVADVALATRSLGW 329
GD VA V L W
Sbjct: 278 VEERPRRPGDPPRLVAGVERIREILEW 304
>UniRef50_A3PE63 Cluster: UDP-glucose 4-epimerase; n=1;
Prochlorococcus marinus str. MIT 9301|Rep: UDP-glucose
4-epimerase - Prochlorococcus marinus (strain MIT 9301)
Length = 330
Score = 182 bits (444), Expect = 1e-44
Identities = 122/348 (35%), Positives = 181/348 (52%), Gaps = 32/348 (9%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+ ++VTGGAGY+GSH T + + V+DNL + +K E
Sbjct: 4 KRIVVTGGAGYIGSHFCKTAFLKGH-----KTFVIDNLITG-------NYDFIKWGE--- 48
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
FYK+DIR + + D ++HFAA V ES+ KPL+Y NI+G ++
Sbjct: 49 -----FYKLDIREESSFKELLLKIKPDYLVHFAASAYVSESIFKPLDYISNNIDGMRSVC 103
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
+I + + +V+SSSC+VYGE + +PINES P SPYG++K FCE+I+K C +
Sbjct: 104 KICSEIKI-PIVFSSSCSVYGEAKNVPINESEPLNP--LSPYGETKLFCEKILK-WCSNA 159
Query: 183 KKWAIISLRYFNPVGAHESGRIGE--DPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+SLRYFN GA E IGE DP +++P + + LK+FG DY T
Sbjct: 160 YGLRWVSLRYFNAAGADEDLEIGEKHDPE---THIIPLAIRALGDSGETLKIFGRDYDTF 216
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DGT VRD+IHV DLA+ H++AI+ + G + + NLG+G G S+ ++ N S
Sbjct: 217 DGTAVRDFIHVMDLASAHLKAIEYLAEGGMS--NIFNLGSGNGTSIKSIINGLENISSKQ 274
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRS-LHDMCRDTWRWQE 347
D + AD++ A L W+ S L ++ R W+W +
Sbjct: 275 VKLKYCERREEDPSCLFADISKAKSILNWQPEFSNLDNILRSAWKWHK 322
>UniRef50_Q8KGE4 Cluster: UDP-glucose 4-epimerase; n=14;
Bacteria|Rep: UDP-glucose 4-epimerase - Chlorobium
tepidum
Length = 329
Score = 179 bits (436), Expect = 9e-44
Identities = 128/340 (37%), Positives = 166/340 (48%), Gaps = 27/340 (7%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LV GGAGY+GSH L+R ++ V DNLS EE
Sbjct: 3 ILVIGGAGYIGSHVAREFLDRG-----YQVTVFDNLSTGR--------------EENLFD 43
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F + DI AE L + N D +H AALKA GES++KP EY NI GT
Sbjct: 44 DAEFVRGDIFDAEMLAEVM-NRGFDGCVHLAALKAAGESMQKPEEYSVHNICGTIGTINQ 102
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
G+ L++SSS ++G P YLPI+E+HP K + YG +K E I+ + K
Sbjct: 103 AVASGIKCLLFSSSAAIFGSPAYLPIDENHP--KKPENYYGFTKLEIERIL-EWYDRLKG 159
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
++RYFN G GRI P NL+P I +VA G L VFG DYPT DGT
Sbjct: 160 LKFAAVRYFNAAGYDVRGRI-RGLERNPANLLPVIMEVASGVRPMLSVFGTDYPTRDGTC 218
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
+RDY+HV DLA HV A + + G + ++NLG+ TG +VLEM+ A +G
Sbjct: 219 IRDYVHVNDLATAHVLAFEQVIESGES--LSVNLGSETGVTVLEMLEAARRLTGKEIMAE 276
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRS-LHDMCRDTW 343
GD VA A+A LGW S L + TW
Sbjct: 277 FAPRRAGDPANLVATSAMARELLGWVPQYSDLDTLVESTW 316
>UniRef50_Q65D61 Cluster: Putative uncharacterized protein; n=1;
Bacillus licheniformis ATCC 14580|Rep: Putative
uncharacterized protein - Bacillus licheniformis (strain
DSM 13 / ATCC 14580)
Length = 331
Score = 179 bits (436), Expect = 9e-44
Identities = 123/354 (34%), Positives = 177/354 (50%), Gaps = 36/354 (10%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
+VLV GGAGY+GSH V TL+E++ +VVVD+L+ + E
Sbjct: 2 SVLVVGGAGYIGSHAVYTLIEKKE-----RVVVVDSLATGHA--------------EAVH 42
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
FYK DIR L ++FEN +I+ V+HFAA + + + NI G TL +
Sbjct: 43 SEAAFYKGDIRDRHFLKQVFENEDIEAVMHFAA-SPISSKSKNVFTSFNENITGMETLLD 101
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+M+++ V ++V++SS VYG PE LP+ E T +GK K+ E+++ + ++K
Sbjct: 102 VMKEYDVGRIVFASSAAVYGSPEDLPVTEE--TEPEPVHAHGKVKWMMEKMLME---AEK 156
Query: 184 KWAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ + + LR FN GAH S IGED G +L+ + + A+G L + + D + D
Sbjct: 157 AYGLKYVILRSFNACGAHPSAIIGED-RGSETHLISNVLRTALGHLPFVHI--DQ--SED 211
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GTGVRDY+HV DLA HV AI H NL G YS +++ A +G
Sbjct: 212 GTGVRDYVHVQDLAEAHVLAIN--HLRKGKDSRIYNLSYGESYSAEQIILAAQYVTGIPL 269
Query: 302 XXXXXXXXXGDVTAN-VADVALATRSLGWRAT-RSLHDMCRDTWRWQEANPNGY 353
D A A + A + LGW SL + RD W W ANPNGY
Sbjct: 270 IAAKLTETDIDSQATFAASSSRARKELGWTPQHNSLIAIIRDAWNWHSANPNGY 323
>UniRef50_Q1GKR7 Cluster: UDP-glucose 4-epimerase; n=17;
Bacteria|Rep: UDP-glucose 4-epimerase - Silicibacter sp.
(strain TM1040)
Length = 327
Score = 178 bits (433), Expect = 2e-43
Identities = 120/345 (34%), Positives = 167/345 (48%), Gaps = 27/345 (7%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGGAGY+GSH L +Q+ P V DNL + +A+K G
Sbjct: 4 VLVTGGAGYIGSHACKAL--KQAGYTP---VTYDNLVTGW-------QDAVK-----FGP 46
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F + D+ LD +F + V+HFAAL VGE++ +P Y+ N+ G+ L E
Sbjct: 47 ---FEQGDLTDRGRLDEVFAQYKPVAVMHFAALSQVGEAMSEPGRYWANNVGGSLCLIEA 103
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
G V+SS+C YGE + + ++E+ P + + YG SK E+I+KD +
Sbjct: 104 AVAAGCLDFVFSSTCATYGEHDNVVLDENTP--QQPLNAYGASKRAVEDILKDFEAAHGL 161
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
++I RYFN GA +GE +L+P + Q G L VFG DY T DGT
Sbjct: 162 RSVI-FRYFNVAGADPEAEVGEFHQP-ETHLVPLMIQAIKGERAALTVFGTDYDTPDGTC 219
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
+RDY+HVCDL H+ +K G NLGTGTG+SV E+++ +
Sbjct: 220 IRDYVHVCDLVDAHILGLKWLEDG--KGSRVFNLGTGTGFSVKEVLSHSHAVTNTEVPHV 277
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHD-MCRDTWRWQEA 348
GD T V+ A LGW RS D M D WRW ++
Sbjct: 278 IGPRRAGDCTKLVSGSVRAGEELGWEPKRSTMDQMISDAWRWHQS 322
>UniRef50_Q011T8 Cluster: Putative UDP-glucose 4-epimerase; n=1;
Ostreococcus tauri|Rep: Putative UDP-glucose 4-epimerase
- Ostreococcus tauri
Length = 430
Score = 177 bits (431), Expect = 4e-43
Identities = 121/349 (34%), Positives = 170/349 (48%), Gaps = 22/349 (6%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTGGAG++GSH V LL R + +DNLS ALKR +
Sbjct: 89 LVTGGAGFIGSHCVKALLARG-----YAVTSMDNLSRG----NGGAIAALKRTADEGSFR 139
Query: 66 VHFYKVDIRCAEALDRIFENHN--IDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
V + D+ E ++ F N +D V HFAA+ VGES+ PL YY+ T L
Sbjct: 140 V--VEGDLGRVEDIEWAFTGSNLGVDVVFHFAAIAYVGESMADPLRYYRNITVNTVNLLR 197
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+M HGV ++YSS+C YG E LPI ES PT K + +PYGKSK + E ++KD +++
Sbjct: 198 VMDAHGVNNMIYSSTCATYGNVEKLPITESTPT-KPI-NPYGKSKLYAENVIKDYALANP 255
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSG---IPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
K+ LRYFN G+ G +GE P + A+G++ +L V G +PT
Sbjct: 256 KFKTAILRYFNVFGSDPDGVLGELPRAELREHGRISGACFDAAMGKVDKLTVMGTKHPTR 315
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DGT +RD++HV DL H+ + N N+GTG+G S+ E V A N +G
Sbjct: 316 DGTTIRDFVHVIDLVDAHIAVAE--KNKWDNPPSLYNVGTGSGVSMREFVDACKNVTGKQ 373
Query: 301 XXXXXXXX-XXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQE 347
GD A+V LGW A L + W++++
Sbjct: 374 IEVYYREEPRPGDYAEVYANVDKIKHELGWSAKYTDLSESLAHAWKFRQ 422
>UniRef50_Q6FB43 Cluster: Putative UDP-galactose 4-epimerase; n=2;
Acinetobacter|Rep: Putative UDP-galactose 4-epimerase -
Acinetobacter sp. (strain ADP1)
Length = 334
Score = 175 bits (426), Expect = 1e-42
Identities = 109/348 (31%), Positives = 179/348 (51%), Gaps = 15/348 (4%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGG G++GSH ++LL + E+++VDNL+NA + L+R+E ++G
Sbjct: 2 ILVTGGLGFLGSHIALSLLAQGQ-----EVILVDNLANASL-------QTLERLEYISGM 49
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ F KVD+R AL+++FE ++ID VIH A+ KA+ ES KPLEYY N++ +L
Sbjct: 50 YIPFVKVDVRNTPALNKVFEQYSIDAVIHTASFKALEESKLKPLEYYNDNVSCIMSLLRS 109
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
M++ GV KLV+ SS VYG+ + E P +PY KS+ EEI++D +D +
Sbjct: 110 MQRTGVRKLVHLSSLMVYGKSS-SKLTEDEPFDTVYPNPYIKSQQMIEEIIRDTFKTDHE 168
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
W I LR N GA E G +GE + +P N++P QVA + L++ T D T
Sbjct: 169 WKIAILRLSNIAGAFEHGVLGEMITQLPKNIIPLAMQVAAMQRDYLEL-QRQADTTDQTV 227
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
R ++HV D+ ++ +Q + + N+ S+ +++ S +
Sbjct: 228 ERSFLHVLDVCEAVFASLYWLNQQD-HCCESFNIAHNEVTSIQQLLEVISQVTQTQINTH 286
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNG 352
++ A++ A + L W+ R+L M W++ + G
Sbjct: 287 DAMYPTEELAQVGANIDKAKQVLNWQPKRTLQQMIEHQWQFYQNTLKG 334
>UniRef50_Q8DGV6 Cluster: UDP-glucose 4-epimerase; n=1;
Synechococcus elongatus|Rep: UDP-glucose 4-epimerase -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 308
Score = 175 bits (425), Expect = 2e-42
Identities = 97/286 (33%), Positives = 146/286 (51%), Gaps = 7/286 (2%)
Query: 72 DIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVY 131
DI LD +F+ + + V+HFAA VGES+ P +YQ N++G TL + M +
Sbjct: 27 DIGDRPLLDWLFQTYPVTAVMHFAAYIEVGESIHSPDRFYQNNVHGALTLLQAMVAAKIP 86
Query: 132 KLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLR 191
++SS+ VYG P +PI+E+ P +PYG+SK+ E+++ D+ + ++I R
Sbjct: 87 YFIFSSTAAVYGVPPEIPISETCPCAP--INPYGRSKWMVEQMVADMGTAYGLKSVI-FR 143
Query: 192 YFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHV 251
YFN GA R+GED +L+P + Q A+GR + ++G DYPT DGT +RDYIHV
Sbjct: 144 YFNAAGADPHSRLGEDHRP-ETHLIPLVLQAAMGRRPHIAIYGTDYPTPDGTCIRDYIHV 202
Query: 252 CDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXG 311
DLA HV+ +K G NLG G+SV +++ +G G
Sbjct: 203 VDLAQAHVRGLKYLLSGG--NSQIFNLGNAQGFSVRQIIETAQRVTGCSIPVIEGDRRAG 260
Query: 312 DVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQEANPNGYHRI 356
D VA+ A LGW+ + + W+W + G H I
Sbjct: 261 DPAILVANSDRARCLLGWQPQYPDIEQIIHHAWQWHQRRHRGNHII 306
>UniRef50_A1SPC3 Cluster: UDP-glucose 4-epimerase precursor; n=2;
Propionibacterineae|Rep: UDP-glucose 4-epimerase
precursor - Nocardioides sp. (strain BAA-499 / JS614)
Length = 334
Score = 175 bits (425), Expect = 2e-42
Identities = 124/348 (35%), Positives = 178/348 (51%), Gaps = 34/348 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGGAGY+GS T L E + P V++D+L P A R + +
Sbjct: 3 VLVTGGAGYIGSTTAKALEE--AGHTP---VILDSLLTG--------PLAFVR-DRI--- 45
Query: 65 TVHFYKVDIRCAEALDRIFENH-NIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
FY+ DI + R+F+ H +ID IH AA V ESVEKP EYY+ N+ + LF+
Sbjct: 46 ---FYEGDIADRALVRRVFDEHPDIDATIHMAARIVVPESVEKPYEYYRDNVAKSLELFD 102
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+ G ++++SSS ++Y + ++E + SPY ++K EE+++D+ +
Sbjct: 103 ELNTLGKGRVLFSSSASIYALKDDFEVSEGDRLEPA--SPYARTKRMMEEVLQDMSAATD 160
Query: 184 KWAIISLRYFNPVGAH---ESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
AII LRYFNP+G+ ESG ++PS + L+ A G+ + G D+PT
Sbjct: 161 LRAII-LRYFNPIGSDPDLESGIYAKEPSHVLGQLV----MAARGQKDAFTITGTDHPTR 215
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQ---PGFNGFHAINLGTGTGYSVLEMVAAFSNAS 297
DGTG+RDYIHV DLA HV+A++ F + IN+GTG+G +V E+V AF N
Sbjct: 216 DGTGIRDYIHVWDLARAHVRAVERFDEVIDAAGEPSVIINVGTGSGVTVRELVTAFQNVF 275
Query: 298 GXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
G GD A+V + R L WR SL D W
Sbjct: 276 GQEVPVREAPPRPGDAVGAFANVDRSGRLLDWRTELSLEDAIASALAW 323
>UniRef50_Q9RSC3 Cluster: UDP-glucose 4-epimerase; n=1; Deinococcus
radiodurans|Rep: UDP-glucose 4-epimerase - Deinococcus
radiodurans
Length = 394
Score = 173 bits (422), Expect = 4e-42
Identities = 120/349 (34%), Positives = 169/349 (48%), Gaps = 25/349 (7%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LV GGAGY+GSHTV RQ E+ V DNLS+ + E L G+
Sbjct: 3 LLVVGGAGYIGSHTV-----RQLRAAGHEVAVFDNLSSGHA-------------EALPGE 44
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V + D+ A ++ E D +IHFAAL VGES+ P YY+ N+ GT L +
Sbjct: 45 -VELIRGDLLDAASIRAALEAQKPDAIIHFAALIEVGESMRAPGRYYRNNVVGTLNLLQS 103
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+ + LV+SS+ VYG + +PI E S YG++K E+++ V+
Sbjct: 104 IVETRKVPLVFSSTAAVYGTTDAVPIPED--AAMQPESVYGETKRMSEQMIHAFHVAHGL 161
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+ LRYFN GA G IGE +L+ A+G+ +++ +FGDDYPT DGT
Sbjct: 162 PYTV-LRYFNVCGAAPGGDIGEAHPN-KTHLIELACLTALGQREKMMIFGDDYPTPDGTC 219
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
+RDY+HV DLA HV A++ H G N+G G G+SV E++ A G
Sbjct: 220 IRDYVHVQDLADAHVLAVEALH-AGKTDAATYNVGLGHGFSVREVLDAVDAVVGTPLQRE 278
Query: 305 XXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQEANPNG 352
GD VAD + LG+ L D+ + W W +P G
Sbjct: 279 LAPRRAGDPPRLVADASRIVDQLGFAPKFTDLRDIVQTAWDWHRTHPQG 327
>UniRef50_Q8G3T3 Cluster: UDP-glucose 4-epimerase; n=5;
Actinobacteridae|Rep: UDP-glucose 4-epimerase -
Bifidobacterium longum
Length = 337
Score = 173 bits (421), Expect = 6e-42
Identities = 131/351 (37%), Positives = 172/351 (49%), Gaps = 34/351 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGG GY+G+H V L + G+ ++VVVD+LS KP ++ L G
Sbjct: 3 VLVTGGCGYIGAHVVHALHQA---GE--KVVVVDDLSYG-------KPTRIEG-SRLYGM 49
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ R AE LD +D VIHFAA K VGESVEKPL YYQ NING +
Sbjct: 50 DIATPGAGERLAEILDA----EGVDSVIHFAARKQVGESVEKPLWYYQQNINGMLNVLTG 105
Query: 125 M-RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
M + KLV+SSS YG P + E + +PYG++K F E M C
Sbjct: 106 MTQSKNAKKLVFSSSAATYGVPPVDVVPEDVVPMLPI-NPYGQTKLF-GEWMARACEQPF 163
Query: 184 KWAIISLRYFNPVGAHESGRIG-EDPSGIPNNLMPYISQVAVGRLKELK---VFGDDYPT 239
+LRYFN G G + EDP+ + NL+P + RLK+ K +FGDDYPT
Sbjct: 164 GIRFCALRYFNVAGC---GPVELEDPAIL--NLIPML----FNRLKQGKAPAIFGDDYPT 214
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
DGT VRDYIHV DLA H+ A+K + + A N+GTG G SV ++V +G
Sbjct: 215 PDGTCVRDYIHVSDLADAHIAALKYLDRDK-RKYDAFNVGTGEGTSVRQIVDEVKKVTGL 273
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANP 350
GD + +GW A + D+ + W +ANP
Sbjct: 274 PFTEAVMARRAGDPPHLIGSPKRINEEMGWHAKYDVEDIVKSAWDAWQANP 324
>UniRef50_A3Q712 Cluster: UDP-glucose 4-epimerase; n=6;
Actinobacteria (class)|Rep: UDP-glucose 4-epimerase -
Mycobacterium sp. (strain JLS)
Length = 329
Score = 172 bits (418), Expect = 1e-41
Identities = 120/349 (34%), Positives = 171/349 (48%), Gaps = 30/349 (8%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTGGAGY+GSH V L E L +VV+D+LS +E+ ++
Sbjct: 4 LVTGGAGYIGSHVVRALTEAD-----LPVVVIDDLSTG--------------LEQFVPES 44
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
V F + + +++ H + VIH A K G SV++PL Y+ N++ TL + M
Sbjct: 45 VPFVRGTLLDGALVEQALREHEVTGVIHIAGFKYAGVSVQRPLHTYEQNVSAMVTLLQAM 104
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
GV K+V+SSS +G P+ ++ES PT SPYG++K E +++D
Sbjct: 105 ETVGVDKIVFSSSAATFGTPDVDQVDESTPTAPE--SPYGETKLIGEWLLRD-AGRASGL 161
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
SLRYFN VG+ + D S P+NL P + + + R ++ GDDYPT DGT V
Sbjct: 162 RHTSLRYFNVVGSGSTALF--DTS--PHNLFPLVFDM-LYRGDTPRINGDDYPTPDGTCV 216
Query: 246 RDYIHVCDLAAGHVQAI-KLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RDY+ V D+A HV A +L + NLG+G G SV E++ A +G
Sbjct: 217 RDYVDVGDVALAHVAAARRLTRSEPVEPVY--NLGSGAGTSVREIMTAIRTVTGVDFEPQ 274
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
GD VA+ LA R L W+ SL DM W ++A Y
Sbjct: 275 IMPRRPGDPARIVANGDLAARDLDWKMRHSLEDMVASAWAARQAAGAAY 323
>UniRef50_UPI00015BC7D2 Cluster: UPI00015BC7D2 related cluster; n=1;
unknown|Rep: UPI00015BC7D2 UniRef100 entry - unknown
Length = 323
Score = 169 bits (410), Expect = 1e-40
Identities = 112/347 (32%), Positives = 180/347 (51%), Gaps = 30/347 (8%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+ + +TGGAGY+GSH + L+R D ++V+DNLS + E +K
Sbjct: 2 KKITITGGAGYIGSHMLKEALKRGYD-----VLVIDNLSTGH-------REFVKG----- 44
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
GK F + D++ E L+ + E D +IHFAA AV ESV++P++YY+ N + L
Sbjct: 45 GK---FLQADMQSKETLEALLE-FKPDAIIHFAAYIAVEESVQEPIKYYENNFCKSLKLL 100
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC-VS 181
E K G+ ++SS+ VYG P+ E+ + +T PYG++K E++++D+ VS
Sbjct: 101 EYTLKAGIKNFIFSSTAAVYGIKSDKPVKETDSI-EPIT-PYGQAKANFEKVLEDVSRVS 158
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
D K+ +++RYFN GA G +G+ S P +L+ + A G +K+ ++G DY T D
Sbjct: 159 DLKY--VAIRYFNVAGADPEGELGQ-ISKKPTHLILRALKAAKGEIKDFGIYGTDYNTKD 215
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GT +RDYIHV DL H +A++ + G + N G G G SV E+V +G
Sbjct: 216 GTCIRDYIHVSDLVDAHFEAMRYLEEGGKS--DVFNCGYGRGLSVKEVVDIVKEVTGVDF 273
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQE 347
GD +A+V + GW+ + + + W W++
Sbjct: 274 PVYNYDRRPGDPPVLIANVDKIKNTFGWKPKYDDPYFIVKTAWEWEK 320
>UniRef50_Q7VJ63 Cluster: UDP-glucose 4-epimerase; n=30;
Epsilonproteobacteria|Rep: UDP-glucose 4-epimerase -
Helicobacter hepaticus
Length = 345
Score = 168 bits (409), Expect = 2e-40
Identities = 109/319 (34%), Positives = 166/319 (52%), Gaps = 27/319 (8%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+L+TG +GY+GSHT LL+ + I++VD+LS + E + ++E +
Sbjct: 4 LLLTGASGYIGSHTAYCLLKNTN----YHILIVDDLSTGF-------KENIAYLQECFEE 52
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V F + +I + + ++ + VIHFAA VGESV KPLEYY N T L +
Sbjct: 53 RVSFVQSNINDISKMRTLLLHYKFEAVIHFAASLIVGESVLKPLEYYTNNTLNTTNLIAL 112
Query: 125 MRKHGVYKLVYSSSCTVYGEP--EYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
+ G+ K ++SS+ VYGEP +PI+E+ P +PYG SK E I+ D ++
Sbjct: 113 CIECGITKFIFSSTAAVYGEPHTSLIPIDENAPL--LPINPYGSSKMMSERILYDTSLAF 170
Query: 183 KKWAIISLRYFNPVGA--HESGRIGEDPSGI------PNNLMPYISQVAVGRLKELKVFG 234
K + ++LRYFN GA + +I + G+ +L+ + A G+ + + +FG
Sbjct: 171 KNFNYVALRYFNVAGASMDNTPQILSNHKGLGQRSKNATHLIKVACECACGKRESMSIFG 230
Query: 235 DDYPTADGTGVRDYIHVCDLAAGHVQAIK-LFHQPGFNGFHAINLGTGTGYSVLEMVAAF 293
DYPT DGT +RDYIH+ DLA+ H++A+ L H N F N+G GYSV E++
Sbjct: 231 TDYPTKDGTCIRDYIHIDDLASAHLEALTFLQHTQTSNIF---NVGYCKGYSVKEVIDVV 287
Query: 294 SNASGXXXXXXXXXXXXGD 312
SG GD
Sbjct: 288 KEISGMDFKVIESARREGD 306
>UniRef50_Q7CS52 Cluster: AGR_L_3011p; n=3; Alphaproteobacteria|Rep:
AGR_L_3011p - Agrobacterium tumefaciens (strain C58 /
ATCC 33970)
Length = 356
Score = 167 bits (407), Expect = 3e-40
Identities = 116/334 (34%), Positives = 159/334 (47%), Gaps = 26/334 (7%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M+R +LVTGGAG++GSH L QS P + DNLS + P
Sbjct: 30 MARTILVTGGAGFIGSHICKALA--QSGFKP---IAYDNLSTGHADSVRWGP-------- 76
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+ DI L + VIH AA VGESVE P +YY+ N+ G+ +
Sbjct: 77 -------LIEGDILDGVLLKATLREFSPAFVIHCAANAYVGESVEDPRKYYRNNVGGSLS 129
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L + + LV+SSSC YG P+ LPI E T + +PYG++K E ++D
Sbjct: 130 LLDACLDQNIGGLVFSSSCATYGVPQQLPIREE--TAQMPVNPYGRTKLIFEMALEDYAA 187
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+ ++LRYFN GA G + E +L+P A RL +L VFG DY T+
Sbjct: 188 A-YGLRFVALRYFNAAGADPDGELYERHEP-ETHLIPRALMAAAARLPQLDVFGADYDTS 245
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DGT +RDYIHV DLA H+ A+ G +NLG+G G SV +++ A +G
Sbjct: 246 DGTCIRDYIHVSDLADAHLAAVNYLSDGGET--LRVNLGSGHGTSVGDIIRAIHRVTGQE 303
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRS 334
GD A AD+ A +LG+ RS
Sbjct: 304 VPVHFGARRAGDPPALFADIRRAEETLGFTPKRS 337
>UniRef50_A4AI37 Cluster: Putative UDP-glucose 4-epimerase; n=1;
marine actinobacterium PHSC20C1|Rep: Putative
UDP-glucose 4-epimerase - marine actinobacterium
PHSC20C1
Length = 322
Score = 167 bits (405), Expect = 5e-40
Identities = 124/342 (36%), Positives = 165/342 (48%), Gaps = 35/342 (10%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
+VTGGAGY+G+HT L ER GD ++VVD+L A P L ++ G
Sbjct: 1 MVTGGAGYIGAHTSRLLAER---GD--YVLVVDDLVTGSRARVPDLP--LVSLDIAAG-- 51
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
A+ L+ + H ID VIHFA K VGESVEKP YY+ N+ L M
Sbjct: 52 ---------AADQLEGLMREHRIDAVIHFAGQKQVGESVEKPAWYYEQNVGSVAQLLIAM 102
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
+ V+KLV+SSS VYGE I E T +PYG +K E++ + S W
Sbjct: 103 QAAQVHKLVFSSSAAVYGEASG-AIAEDATTNP--INPYGATKLVGEQL---ISASSLAW 156
Query: 186 AI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPY-ISQVAVGRLKELKVFGDDYPTADG 242
+ SLRYFN VG S +G+ + NL+P Q+A K +FG+DY T DG
Sbjct: 157 PLRAASLRYFN-VGGAGSPELGDTQA---LNLIPICFEQIAAN--KPPLIFGEDYDTPDG 210
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
T VRDY+HV D+A H+ + P G +N+GTG G +V +MV A SG
Sbjct: 211 TCVRDYVHVSDVAEAHLAVLDAL--PAQPGNTVLNIGTGVGTTVRQMVEAILQVSGSELT 268
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWR 344
GD A V V GW A ++ D+ W+
Sbjct: 269 ATVLDRRTGDPAAVVGIVDNIRELTGWSARFTVDDIVESAWQ 310
>UniRef50_Q0BRM8 Cluster: UDP-glucose 4-epimerase; n=2;
Rhodospirillales|Rep: UDP-glucose 4-epimerase -
Granulobacter bethesdensis (strain ATCC BAA-1260 /
CGDNIH1)
Length = 342
Score = 166 bits (404), Expect = 7e-40
Identities = 124/352 (35%), Positives = 166/352 (47%), Gaps = 32/352 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAGYVGSHTV L +R GD E+ V D+L +G + +AL
Sbjct: 17 LLVTGGAGYVGSHTVWALHDR---GD--EVTVYDSLF-----QGHR--QALP-------P 57
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V D+ L D V+HFAA VGES+ P+ Y N L
Sbjct: 58 GVRLVVADLADETTLHATLAEGQWDGVMHFAARSLVGESMVDPMLYMNQNAALGFKLIAA 117
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+H V + + SS+ ++G + PI+E+ SPYG+SK E + L +D+
Sbjct: 118 CVQHKVPRFLLSSTAALFGHHDDTPIDENAAIQPG--SPYGESKLMIE---RALSWADRI 172
Query: 185 WAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ LRYFN GA GR GED +L+P + A+G E+KVFG DYPT DG
Sbjct: 173 HGLRYACLRYFNAAGADPQGRSGEDHDP-ETHLIPLVIDAALGLRPEIKVFGHDYPTRDG 231
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
T +RDYIHV DLA H+ A+ Q G NLG G GYSV+E++ + SG
Sbjct: 232 TCIRDYIHVSDLAQAHLAALTRIDQ----GSTVYNLGNGAGYSVMEVIHSVERVSGLTVP 287
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQEANPNGY 353
GD VA R GW +L D+ W+ A+P G+
Sbjct: 288 MRIEARRPGDPAVLVASAEKIRRETGWTPRFPALDDIVATALAWRRAHPQGF 339
>UniRef50_A0L5P6 Cluster: UDP-glucose 4-epimerase; n=4;
Bacteria|Rep: UDP-glucose 4-epimerase - Magnetococcus
sp. (strain MC-1)
Length = 337
Score = 164 bits (399), Expect = 3e-39
Identities = 112/346 (32%), Positives = 166/346 (47%), Gaps = 29/346 (8%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+A+LVTGGAGY+GSH L QS P + DNLS + P A++ +
Sbjct: 2 KAILVTGGAGYIGSHVCKVL--SQSGFLP---ITYDNLSEGH-------PWAVRWGPLVV 49
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
G + L +F + VIH A VGES+ P YY+ N+ L
Sbjct: 50 G--------GLDDGAKLAGLFAQYQPQAVIHLAGRAYVGESMTDPALYYRNNVQAALVLL 101
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
E MR++G +++SSSC YGE +PI E+ + +PYG+SK E +++D V
Sbjct: 102 ECMRQYGCKNIIFSSSCATYGEHRQMPITEA--MSQHPINPYGRSKLMFEWMLQDYQVYG 159
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ ++LRYFN GA G IGE P +++P + + A + ++G DY + DG
Sbjct: 160 LQ--SVALRYFNASGADLEGEIGEQHQPEP-HIIPRLLE-AARKGSPFTIYGTDYESEDG 215
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
T VRDYIHV DLA H+ A++ + G + A NLG G G+S+ +++ +G
Sbjct: 216 TCVRDYIHVSDLAQAHLLALQWLWRGGES--RAFNLGNGQGFSIRQLIKVAETVTGKSIA 273
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQE 347
GD V A LGW+ +L + WRW +
Sbjct: 274 VQLGARRPGDPAVLVGSAEKAREELGWQPQYGTLEIILTSAWRWMQ 319
>UniRef50_Q07GF0 Cluster: UDP-glucose 4-epimerase; n=1; Roseobacter
denitrificans OCh 114|Rep: UDP-glucose 4-epimerase -
Roseobacter denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 342
Score = 163 bits (396), Expect = 6e-39
Identities = 105/294 (35%), Positives = 158/294 (53%), Gaps = 27/294 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+L+TGGAGYVGS + + E+ D ++V D+L + + P
Sbjct: 3 ILITGGAGYVGSACLRYVAEQGHD-----VMVYDSLVMGHRRAVDGHP------------ 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ DI L + ++ D V+HFAA VGESVE P YY+ N++GT +L
Sbjct: 46 ---LVRGDIADTALLTQTLKDFGADAVMHFAAATYVGESVENPEYYYRNNVSGTLSLLNA 102
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
MR GV +L++SS+C YG E ++E+ P SPY ++K E +++D +
Sbjct: 103 MRAAGVNRLLFSSTCATYGMAEADTMSEATPLDP--FSPYARTKLAVEWMIRDFAHA-YG 159
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
LRYFN GA GR GED + ++L+P + QV +G+ ++ VFGDDYPT DGT
Sbjct: 160 MGFTLLRYFNASGADADGRHGEDHTP-ESHLIPLVLQVPLGQRDKIMVFGDDYPTPDGTC 218
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
+RDY+H DLA+ H+ AI+ + G + N+GTG G SV++++ A G
Sbjct: 219 IRDYVHTRDLASAHLLAIEA-TEVGTD--EIFNIGTGNGQSVMQIIEACETCHG 269
>UniRef50_Q9L047 Cluster: UDP-glucose 4-epimerase; n=7;
Actinomycetales|Rep: UDP-glucose 4-epimerase -
Streptomyces coelicolor
Length = 326
Score = 160 bits (389), Expect = 4e-38
Identities = 119/347 (34%), Positives = 167/347 (48%), Gaps = 31/347 (8%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
L+TGGAGY+G+H V + E G+ + VV D+LS E+ P+ + + G
Sbjct: 4 LITGGAGYIGAHVVRAMTEA---GE--KAVVYDDLSTGIA---ERVPDGVPLV---VGSV 52
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+ E + R +H++ V+H AA K VGESV+ PL YY+ N+ G L + +
Sbjct: 53 LD--------GERVARALADHSVTGVVHLAAKKQVGESVDLPLHYYRQNVEGLRVLLDAV 104
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
GV V+SSS VYG P+ + E P SPYG++K E +++
Sbjct: 105 TAAGVPSFVFSSSAAVYGMPDVDLVTEETPCVP--MSPYGETKLAGEWLVR-ATGRATGL 161
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
A SLRYFN GA + +G+ NL+P + + + ++FGDDY T DGT V
Sbjct: 162 ATASLRYFNVAGAASPDLV---DTGV-YNLVPMVFE-KLTESAAPRIFGDDYATPDGTCV 216
Query: 246 RDYIHVCDLAAGHVQAIK-LFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RDYIHV DLA HV A + L PG +N+G G G SV EM+ + +G
Sbjct: 217 RDYIHVVDLAEAHVAAARALQSSPG--TALTLNIGRGEGVSVREMIDRINAVTGCDQPPT 274
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWR-WQEANP 350
GD VA A LGW+A + DM W W +P
Sbjct: 275 VTPRRPGDPARVVASADRAAVELGWKAKYDVEDMITSAWAGWVRLHP 321
>UniRef50_P72903 Cluster: UDP-glucose-4-epimerase; n=20;
Bacteria|Rep: UDP-glucose-4-epimerase - Synechocystis
sp. (strain PCC 6803)
Length = 340
Score = 159 bits (387), Expect = 8e-38
Identities = 115/343 (33%), Positives = 161/343 (46%), Gaps = 27/343 (7%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAGY+GS V RQ IVV DN S + P ++ + + G
Sbjct: 9 ILVTGGAGYIGSSVV-----RQLGEAGYSIVVYDNCSTGF-------PSSILYGQLVIG- 55
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
D+ E L ++F H I V+HFA V ES+ PL YY N + T +L
Sbjct: 56 -------DLADTERLHQVFHEHEILAVMHFAGSLIVPESLIHPLNYYANNTSNTLSLIRC 108
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+ GV +L++SS+ VYG PI+E+ +PYG+SK E I++D S
Sbjct: 109 CQIFGVNRLIFSSTAAVYGNSSSNPISEAEI--PCPINPYGRSKLASEWIIQDYAKSSAL 166
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+I LRYFN GA GR+G+ S +L+ + + L +FG D+PT DGT
Sbjct: 167 QYVI-LRYFNVAGADPEGRLGQ-MSKTTTHLVRSVCDAILNLKPSLDIFGTDFPTRDGTA 224
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
VRDYIHV DLA H+ A++ G + +N G G GYSV E+V SG
Sbjct: 225 VRDYIHVEDLAKAHLDALRYLENGGES--QILNCGYGQGYSVREVVDRAKAISGVDFLVR 282
Query: 305 XXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRWQ 346
GD + +A + L W +L + R W+
Sbjct: 283 ETERRLGDPASVIACADSIRQVLNWTPKYNNLDIILRTALAWE 325
>UniRef50_A2BZ28 Cluster: UDP-glucose 4-epimerase; n=1;
Prochlorococcus marinus str. MIT 9515|Rep: UDP-glucose
4-epimerase - Prochlorococcus marinus (strain MIT 9515)
Length = 348
Score = 159 bits (387), Expect = 8e-38
Identities = 118/349 (33%), Positives = 172/349 (49%), Gaps = 23/349 (6%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
V+V GGAGY+GSHTV E Q++G E +V+DNL + E I ++ K
Sbjct: 4 VIVAGGAGYIGSHTV---RELQNEG--FEPIVLDNLVYGHRNIVEDVLAVPLVIGQVGDK 58
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ K L R +I ++HFAA VGESV P +YY+ N+ T +L E
Sbjct: 59 PL--LKKLFSGEHPLTR---GKDIKGIMHFAAYAYVGESVVDPAKYYKNNLVETISLLEA 113
Query: 125 M------RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL 178
+ R +V+SSSC YG P I T ++ +PYG+SK E+I+ D
Sbjct: 114 LLEDSKKRNSQPIPIVFSSSCATYGIPLEAEIPIIERTPQNPINPYGRSKLMMEKILIDY 173
Query: 179 CVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYP 238
+ + + LRYFN GA +G IGED + +L+P + + + LKV G DYP
Sbjct: 174 HKA-YELPVSILRYFNAAGADINGDIGEDHNP-ETHLIPLVLEALSDKEGFLKVNGIDYP 231
Query: 239 TADGTGVRDYIHVCDLAAGHVQAI-KLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNAS 297
T DGT +RDY+HV DLA HV A+ K+ + + + NLG G GYS++E++ A +
Sbjct: 232 TFDGTCIRDYVHVSDLAKAHVLALNKIMNDKSLSIY---NLGNGKGYSIMEVIDASKKVT 288
Query: 298 GXXXXXXXXXXXXGDVTANVADVALATRSLGWRAT-RSLHDMCRDTWRW 345
G GD ++ A + L W+ + L + R W W
Sbjct: 289 GKEIRILQSKRRQGDPPVLISSPEKAKKELLWKPEFQDLESIIRTAWNW 337
>UniRef50_A0LJ03 Cluster: UDP-glucose 4-epimerase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: UDP-glucose
4-epimerase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 318
Score = 159 bits (387), Expect = 8e-38
Identities = 106/287 (36%), Positives = 151/287 (52%), Gaps = 30/287 (10%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAGY+GSHT + L R++ P + DNLSN + P
Sbjct: 3 ILVTGGAGYIGSHT--SKLLRKAGHTP---IAFDNLSNGWAELVRFGP------------ 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F DIR EAL R E +D VIHFAA V ES P EY+ N+ GT L +
Sbjct: 46 ---FVFGDIRNEEALARALEVFKVDAVIHFAAKAYVEESTRLPEEYFDNNVGGTVALLKA 102
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC-VSDK 183
M++ G LV+SSSC YG I E+HP + T+PYG SK CE+++ + V+
Sbjct: 103 MKRAGTKTLVFSSSCATYGNARTPTIKENHP--QEPTNPYGLSKLMCEQVISTVAPVAGI 160
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
++A +LRYFN +G G + E +++P + + + E ++G ++PT DGT
Sbjct: 161 RFA--ALRYFNVIGGDPEGEVYERHEP-ETHVLPNLMKAGLSG-AEFSLYGTNHPTPDGT 216
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMV 290
VRDY++V DLAA HV+A+ + N+G G G SV E++
Sbjct: 217 AVRDYVYVMDLAAAHVKALDVLRA---RDRLISNVGRGRGTSVRELL 260
>UniRef50_Q4Q3V7 Cluster: Udp-glc 4'-epimerase, putative; n=7;
Trypanosomatidae|Rep: Udp-glc 4'-epimerase, putative -
Leishmania major
Length = 391
Score = 159 bits (386), Expect = 1e-37
Identities = 130/392 (33%), Positives = 183/392 (46%), Gaps = 49/392 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAE----GEKKPEALK---R 57
VLV GG GY+G+H V LL R S P ++++ D+L + ++ EK A
Sbjct: 3 VLVCGGVGYIGTHFVRELL-RYS---PHDVIIADSLEATHGSDVHVDTEKNYAARNPGAN 58
Query: 58 IEELTGKTVHFYKV---DIRCAEALDRIFENHN-IDCVIHFAALKAVGESVEKPLEYYQV 113
+EE+ F K+ D+R + L+ +F H ID V+H A V ESV PL YY
Sbjct: 59 LEEVKRSGYRFAKLEVGDVRDVDFLEHVFTTHAPIDAVVHMCAHIVVPESVRDPLRYYDN 118
Query: 114 NINGTCTLFEIMRKHGVYKLVYSSSCTVYGEP----------EYLPINESHPTGKSL-TS 162
N+ G + +IM K+ KL+ SS+ ++G P E P+ K + S
Sbjct: 119 NVVGMLRILQIMLKYKCDKLILSSTAALFGNPYARMRAGSTDEPDPMKPIRSNAKCMPES 178
Query: 163 PYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQV 222
PYG +K E ++KD C + + LRYFN GA G IGE ++L+P I +V
Sbjct: 179 PYGTTKLVGEYMLKD-CAAAYGIKSVCLRYFNACGADAEGDIGETHEP-ESHLIPLILRV 236
Query: 223 ----------AVGRLKELKV------FGDDYPTADGTGVRDYIHVCDLAAGHVQAI---- 262
AV + KV FG DYPT DGT +RDY+HV DL++ HV+A+
Sbjct: 237 PLADKINAYNAVHHPERQKVNGYVSIFGTDYPTPDGTCIRDYVHVKDLSSAHVRALDYLA 296
Query: 263 KLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVAL 322
KL F NLGT GYSV E++ A +G GD VA
Sbjct: 297 KLTPDDKDRFFSTFNLGTSKGYSVREVIEAARRVTGHPIPEREEKRRDGDPPVLVASGEE 356
Query: 323 ATRSLGWRAT-RSLHDMCRDTWRWQEANPNGY 353
A +LGW S+ + W++ +P GY
Sbjct: 357 AAAALGWTLEYESIDKIIESAWKFHSKHPVGY 388
>UniRef50_A6PV21 Cluster: UDP-glucose 4-epimerase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: UDP-glucose 4-epimerase -
Victivallis vadensis ATCC BAA-548
Length = 307
Score = 154 bits (373), Expect = 4e-36
Identities = 98/279 (35%), Positives = 141/279 (50%), Gaps = 15/279 (5%)
Query: 77 EALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVYS 136
E + + D ++HFAA VGES++ P +Y++ NI L + + GV V+S
Sbjct: 40 EKIKSVCREGKFDAIMHFAAFSLVGESMKDPSKYFRNNIANGINLADAAVESGVKMFVFS 99
Query: 137 SSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC-VSDKKWAIISLRYFNP 195
S+ +G+PE +PI E + +PYG+SK E+I+K + +A +LRYFN
Sbjct: 100 STAATFGQPESIPIKEFDR--QIPINPYGESKLCFEKILKWYHEIYGINYA--ALRYFNA 155
Query: 196 VGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLA 255
GA E+ GED +L+P I Q G+ +L ++GDDY TADGT VRDYIH+ DLA
Sbjct: 156 AGATEN--FGEDHRP-ETHLIPLILQTVRGKRDKLMLYGDDYDTADGTCVRDYIHILDLA 212
Query: 256 AGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTA 315
H A+ + NLGTG G SV E++ A + +G GD
Sbjct: 213 QAHELALSAPESGHY------NLGTGNGLSVREIIDAAEDVTGLKVNYEVAPRRPGDPAK 266
Query: 316 NVADVALATRSLGWRAT-RSLHDMCRDTWRWQEANPNGY 353
+A A R L W S H + W+WQ +P+GY
Sbjct: 267 LIACSERARRMLKWEPKYESAHKIIESAWKWQLKHPDGY 305
>UniRef50_A3VS38 Cluster: UDP-glucose 4-epimerase; n=2;
Alphaproteobacteria|Rep: UDP-glucose 4-epimerase -
Parvularcula bermudensis HTCC2503
Length = 328
Score = 154 bits (373), Expect = 4e-36
Identities = 115/346 (33%), Positives = 162/346 (46%), Gaps = 30/346 (8%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+ VTG GY+GSH +++L +R D + AE P AL L+
Sbjct: 3 IAVTGATGYLGSHMLLSLHDRGVDAVGV-------------AESGTLPPALLNHVLLSIL 49
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAV-GESVEKPLEYYQVNINGTCTLFE 123
+ D+ + L +FE H++ VIHFA A S+ P+ Y + T T
Sbjct: 50 S----SADV---QGLATVFETHDVTGVIHFAGNDATPAGSLIDPMAQYDQILTPTLTALR 102
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
G+ V+SS+ +VYG P+ +PI E P S SP+G + E I+ D+C
Sbjct: 103 AATLRGIEHFVFSSTASVYGVPQRMPIREETPL--SPISPFGAAMGMAERIVADVCRPAC 160
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKE-LKVFGDDYPTADG 242
I LRYFN GA + R GE +G P +L+ +Q+A G L E LK++G+DY T DG
Sbjct: 161 IGTAI-LRYFNVAGADPNARAGE--TGHPRHLIKAAAQIATGVLNEPLKIYGNDYNTPDG 217
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
T +RDYIHV D+A H A L H G +N G G G SV E++AA +G
Sbjct: 218 TCIRDYIHVSDMAEAHATA--LDHLMAGGGSVTLNCGYGRGISVHEVIAAVQRVTGKTLP 275
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHD-MCRDTWRWQE 347
GD +AD A +L W D + R +W+E
Sbjct: 276 TQYAARRQGDAPLLIADTAAIRTALSWVPRYDDIDVIIRSAIQWEE 321
>UniRef50_Q0C2X5 Cluster: UDP-glucose 4-epimerase; n=1; Hyphomonas
neptunium ATCC 15444|Rep: UDP-glucose 4-epimerase -
Hyphomonas neptunium (strain ATCC 15444)
Length = 335
Score = 149 bits (362), Expect = 8e-35
Identities = 115/336 (34%), Positives = 155/336 (46%), Gaps = 30/336 (8%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M VLV GGAGYVGSH E D + V DNLS + L R
Sbjct: 1 MPGKVLVLGGAGYVGSHCCRAFSEAGWD-----VTVFDNLSTGW--------RDLVR--- 44
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
GK + + D+ ++ F D V HFAA VGESV +P +YY+ N T
Sbjct: 45 -WGKLI---EGDLNSPGDIEAAFSAIKPDAVAHFAASTLVGESVTEPGKYYRNNTFTTLN 100
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
+ + M++H +++SS+C ++G + + E HP K+ +PYG SK E+++
Sbjct: 101 VLDAMQRHNTRAIIFSSTCAIFGHAQTEFLAEDHP--KNPINPYGMSKLMVEQMLAGF-- 156
Query: 181 SDKKWAIIS--LRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYP 238
D I S LRYFN GA GE +L+P + A + G D+
Sbjct: 157 -DHAHGIRSACLRYFNAAGADRQALTGE-RHACETHLIPLALKGAYDPGYSFTITGTDFD 214
Query: 239 TADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
T DGT +RDYIHV DLA H+ A+ Q + +A NLGTG G SV E+V A A+G
Sbjct: 215 TPDGTALRDYIHVEDLAEAHLLALNALEQGAPS--NAFNLGTGRGTSVAEIVDAVERATG 272
Query: 299 XXXXXXXXXXXXGDVTANVADVALATRSLGWRATRS 334
GD +A A LGW A RS
Sbjct: 273 RRLPRKIGPRRPGDAARLIAAPGRAKDVLGWTAKRS 308
>UniRef50_Q97NY4 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=12; Streptococcus pneumoniae|Rep:
NAD-dependent epimerase/dehydratase family protein -
Streptococcus pneumoniae
Length = 233
Score = 131 bits (317), Expect = 2e-29
Identities = 83/256 (32%), Positives = 133/256 (51%), Gaps = 24/256 (9%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M++ +LVTGG Y+GSHTV LL ++ V+DNLS A + +
Sbjct: 1 MTKTILVTGGTSYIGSHTVKALLNA-----GYQVHVLDNLSTGNRAAVDSR--------- 46
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
F ++D+ A AL E + ID V+H A V ES+E P +Y+ N+ G
Sbjct: 47 -----ASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQ 101
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEY-LPINESHPTGKSLTSPYGKSKYFCEEIMKDLC 179
+ +++ + G+ K+++SS+ ++YG P+ E T +PY ++K E ++ +
Sbjct: 102 VLKVLSEVGIQKIMFSSTASLYGNNCIDKPVTED--TLLDPVNPYAETKLMGERMIYWM- 158
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+ W + RYFN GA G P +++P I++ A+G+ LK+FGDDY T
Sbjct: 159 ANRYDWKYVIFRYFNVAGAEMDASNGLRVKN-PTHIIPNINKTALGQNDSLKIFGDDYDT 217
Query: 240 ADGTGVRDYIHVCDLA 255
DG+ +RDYI+V DLA
Sbjct: 218 RDGSCIRDYIYVLDLA 233
>UniRef50_A6QU99 Cluster: UDP-glucose 4-epimerase; n=1; Ajellomyces
capsulatus NAm1|Rep: UDP-glucose 4-epimerase -
Ajellomyces capsulatus NAm1
Length = 286
Score = 129 bits (312), Expect = 9e-29
Identities = 62/145 (42%), Positives = 84/145 (57%), Gaps = 1/145 (0%)
Query: 211 IPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGF 270
+ N + + VA G+ ++L V+GDDY + DGT +RDYIH+ DLAAGH+QA+ +
Sbjct: 129 VTNIVFSSSATVATGKREKLLVYGDDYASHDGTAIRDYIHILDLAAGHLQALNYLRE-NH 187
Query: 271 NGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWR 330
G A NLGTG G +V M+ AFS A G GDV + + A R LGW+
Sbjct: 188 PGVRAWNLGTGKGSTVFHMIKAFSAAVGRDLPYEVVGRRAGDVLDLTGNPSRANRELGWK 247
Query: 331 ATRSLHDMCRDTWRWQEANPNGYHR 355
ATR+L + C D WRW + NP GY +
Sbjct: 248 ATRTLEEACEDLWRWTKNNPAGYRQ 272
Score = 109 bits (261), Expect = 1e-22
Identities = 63/138 (45%), Positives = 83/138 (60%), Gaps = 13/138 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
V+ G GY+GS T + LLE ++V+ DNL N+ EA+ RI + G+
Sbjct: 15 VVKPSGTGYIGSFTALALLEAG-----YKVVIADNLYNS-------SDEAINRIGLICGR 62
Query: 65 TVHFYKVDIRCAEALDRIFENH-NIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
F K+DI LDR FE + +ID VIHFAALKAVGES EKPL+YY VN+ G+ L
Sbjct: 63 RPGFVKIDITNEADLDRAFEQYPDIDSVIHFAALKAVGESGEKPLDYYYVNVYGSICLLR 122
Query: 124 IMRKHGVYKLVYSSSCTV 141
M++H V +V+SSS TV
Sbjct: 123 AMKRHNVTNIVFSSSATV 140
>UniRef50_P47364 Cluster: UDP-glucose 4-epimerase; n=4;
Mycoplasma|Rep: UDP-glucose 4-epimerase - Mycoplasma
genitalium
Length = 340
Score = 129 bits (312), Expect = 9e-29
Identities = 107/348 (30%), Positives = 159/348 (45%), Gaps = 27/348 (7%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
V + GG GY+GS + ++ Q+D L + V+DN N + + LK+I
Sbjct: 8 VAIVGGIGYIGS-CFASFIKEQND--KLIVTVIDNNKNNHVIK------LLKKIG----- 53
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE- 123
+ FY D+ L + D V HFAA +V ESV PL+Y+ N+ GT L
Sbjct: 54 -IEFYFADLLDRHKLTEVIAAIQPDVVFHFAAKTSVSESVHNPLKYFDCNVIGTLNLISA 112
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHP-TGKSLTSPYGKSKYFCEEIMKDLCVSD 182
I KL ++SS VYG+ I+E T T+PYG SK F +E++ + +
Sbjct: 113 ISNLQKPIKLFFASSAAVYGQTTNSYISEEIVITETQATNPYGLSK-FLDELILNAVAKN 171
Query: 183 KKWAIISLRYFNPVGAH-ESGRI-GEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+ ++ LR+FN GA G G IPN + ++ Q ++G+DY T
Sbjct: 172 SQLQVVCLRFFNVAGAILPFGNFNGNTTLLIPNLVKAFLKQTP------FFLYGNDYATK 225
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMV-AAFSNASGX 299
DG+ +RDYIHV D+ H K + F NLG+G G S LE++ A
Sbjct: 226 DGSCIRDYIHVYDICNAHFLLWKWLNDHRQIKFETFNLGSGIGTSNLEVIDIAKKVFYPS 285
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQE 347
D VA+VA A ++ ++ TR+L DM D + E
Sbjct: 286 RLNLEIRPKRSWDPAILVANVAKAKQTFQFKITRNLKDMISDERNFYE 333
>UniRef50_Q8TXF0 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=1; Methanopyrus kandleri|Rep:
Nucleoside-diphosphate-sugar epimerase - Methanopyrus
kandleri
Length = 309
Score = 128 bits (310), Expect = 2e-28
Identities = 106/342 (30%), Positives = 157/342 (45%), Gaps = 41/342 (11%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++GSH V L++R D +VV+DN S C E L+ + +
Sbjct: 2 ILVTGGAGFIGSHVVEELVDRGHD-----VVVLDNFSVG-CEEN------LREVRD---- 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ + D+ A++R F + + VIH AA V S+E P ++N GT L +
Sbjct: 46 DIEIVRADVTDPRAVERTFREYRPEAVIHLAAQVNVRYSMESPFVDARINALGTLNLVSL 105
Query: 125 MRKHGVYKLVYSSS-CTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+H V + VY+SS VYGEPEYLP++E HPT S YG SK E ++ D
Sbjct: 106 AAEHDVERFVYASSGGAVYGEPEYLPVDEEHPTRP--ISNYGVSKLAGEYYVRVYAERD- 162
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
+ + LRY N G +DP G + ++ + A G + L +FG DG
Sbjct: 163 GFEYVILRYANVYGPR------QDPRGEAGVIPIFLLRAARG--EPLTIFG------DGE 208
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RD++ V D+A +A++ G N+GTG SV ++V A +G
Sbjct: 209 QTRDFVFVEDVARVTAEAVE-------RGDGVYNIGTGRETSVNDIVNAVKAVTGVDVEV 261
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
G+V D + A LG+ L + TW W
Sbjct: 262 VYEDPRPGEVRRIYLDPSRAREELGFEPRVDLEEGIERTWEW 303
>UniRef50_Q57664 Cluster: Putative UDP-glucose 4-epimerase; n=3;
cellular organisms|Rep: Putative UDP-glucose 4-epimerase
- Methanococcus jannaschii
Length = 305
Score = 125 bits (302), Expect = 2e-27
Identities = 106/348 (30%), Positives = 166/348 (47%), Gaps = 50/348 (14%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++GSH V L+E D ++++DNL+ + P+A
Sbjct: 2 ILVTGGAGFIGSHIVDKLIENNYD-----VIILDNLTTGN--KNNINPKA---------- 44
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F DIR + LD +++ VIH AA V SVE P+ +N+ GT + E+
Sbjct: 45 --EFVNADIRDKD-LDEKINFKDVEVVIHQAAQINVRNSVENPVYDGDINVLGTINILEM 101
Query: 125 MRKHGVYKLVYSSS-CTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
MRK+ + K+V++SS VYGEP YLP++E+HP SPYG SKY EE +K + ++
Sbjct: 102 MRKYDIDKIVFASSGGAVYGEPNYLPVDENHPINP--LSPYGLSKYVGEEYIK---LYNR 156
Query: 184 KWAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ I LRY N G +DP G + +I ++ + + +FG D
Sbjct: 157 LYGIEYAILRYSNVYGER------QDPKGEAGVISIFIDKML--KNQSPIIFG------D 202
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
G RD+++V D+A ++ A+ ++ +N+GTG SV E+ + G
Sbjct: 203 GNQTRDFVYVGDVAKANLMALNWKNE-------IVNIGTGKETSVNELFDIIKHEIGFRG 255
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
G+V D+ A SLGW+ L + + W + N
Sbjct: 256 EAIYDKPREGEVYRIYLDIKKA-ESLGWKPEIDLKEGIKRVVNWMKNN 302
>UniRef50_Q5SKQ2 Cluster: UDP-glucose 4-epimerase; n=4; Thermus|Rep:
UDP-glucose 4-epimerase - Thermus thermophilus (strain
HB8 / ATCC 27634 / DSM 579)
Length = 311
Score = 117 bits (282), Expect = 4e-25
Identities = 111/329 (33%), Positives = 158/329 (48%), Gaps = 43/329 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGGAG++GSH V LL R LE+ V+DNL A G++ E K
Sbjct: 3 VLVTGGAGFIGSHIVEDLLARG-----LEVAVLDNL-----ATGKR---------ENVPK 43
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V F++VD+R E ++R F V H AA +V SVE P+ ++VN+ G L E
Sbjct: 44 GVPFFRVDLRDKEGVERAFREFRPTHVSHQAAQASVKVSVEDPVLDFEVNLLGGLNLLEA 103
Query: 125 MRKHGVYKLVYSSS-CTVYGE-PEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS- 181
R++GV KLV++S+ +YGE PE E+ P SPY SK E + S
Sbjct: 104 CRQYGVEKLVFASTGGAIYGEVPEGERAEETWPPRPK--SPYAASKAAFEHYLSVYGQSY 161
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
KW +SLRY N G +DP G + + +V G + ++ P +
Sbjct: 162 GLKW--VSLRYGNVYGPR------QDPHGEAGVVAIFAERVLKG--LPVTLYARKTPGDE 211
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
G VRDY++V D+A H A+ LF G N+GTG G++ E++ A + A+G
Sbjct: 212 GC-VRDYVYVGDVAEAH--ALALFSLEGI-----YNVGTGEGHTTREVLMAVAEAAGKAP 263
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWR 330
GD+ +V L + GWR
Sbjct: 264 EVQPAPPRPGDLERSVLS-PLKLMAHGWR 291
>UniRef50_A7CY79 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Opitutaceae bacterium TAV2|Rep: NAD-dependent
epimerase/dehydratase - Opitutaceae bacterium TAV2
Length = 349
Score = 114 bits (275), Expect = 3e-24
Identities = 104/348 (29%), Positives = 150/348 (43%), Gaps = 34/348 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKR--IEELT 62
+LVTGGAG++GSH LL +DG L VV+D+ ++ Y P ALK + +
Sbjct: 22 ILVTGGAGFIGSHLCEALL---ADGHHL--VVLDDFNDYY-------PPALKHAHLAPIR 69
Query: 63 GKTVHFYKVDIRCAEALDRIFENHN-IDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
+ + DIR A++R F H+ I V H AA V S+ P Y NI+GT L
Sbjct: 70 DQLDALVQADIRDPAAIERTFATHHPIHAVYHLAARAGVRPSIHSPRLYLSTNIDGTLNL 129
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
E R H V + +SS +VYG P E+ P ++L SPY SK E++ +
Sbjct: 130 LEACRAHHVPDFILASSSSVYGANPKTPFAETDPIQRTL-SPYAASKLAAEQLCSNY-AH 187
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ LR F G + + + + + + GR + ++G D
Sbjct: 188 LHGLRCLCLRLFTVYGPRQRPDLA---------IARFTAAIRDGR--PIDLYG------D 230
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
GT RDY +V D+ G + A + F NLG ++ E+V NA G
Sbjct: 231 GTTARDYTYVDDIIQGLLAAGRRTATLPPATFEIFNLGESATTTLNELVTLIENALGRPA 290
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
GDV AD++ A R LG+ D R RW E N
Sbjct: 291 LIRRQPEQPGDVPRTYADISKARRLLGYAPATLPADGIRKYIRWLETN 338
>UniRef50_A1HMB7 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Thermosinus carboxydivorans Nor1|Rep: NAD-dependent
epimerase/dehydratase - Thermosinus carboxydivorans Nor1
Length = 307
Score = 112 bits (270), Expect = 1e-23
Identities = 101/343 (29%), Positives = 163/343 (47%), Gaps = 46/343 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++GSHTV L+ + ++ VVD+LS R E + +
Sbjct: 3 ILVTGGAGFIGSHTVDKLIH-----EGCQVTVVDDLSTG-------------RRENVNAQ 44
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F ++D+ C+ L +F N D V+H AA +V S++KP +VN+ GT + E+
Sbjct: 45 AT-FIEMDV-CSPVLFELFANVKFDGVVHLAAQTSVPVSMDKPDFDCRVNVLGTVNVLEV 102
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
R+ GV ++V +SS VYG+ +P+ E + S YG SK E L + +
Sbjct: 103 CRRFGVRRVVLASSAAVYGDGVAVPVREDAKMAPA--SVYGLSKLTAETY---LSMYTRL 157
Query: 185 WAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ + + LRY N G + G GE G+ + + S++A G + L V+GD Y T
Sbjct: 158 FGLEGVVLRYANVYGERQ-GDGGE--GGV---VSIFTSRMARG--EALTVYGDGYQT--- 206
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
RD+++ D+A + A+ P NG N+GT + SV +++ ++ +G
Sbjct: 207 ---RDFVYAGDVANANWLAL---ITPDVNG--VFNVGTASETSVNDLIQLLTDVAGRTVD 258
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GD+ + D LA L W+ L + TW W
Sbjct: 259 IQYCTPRHGDIYRSALDNRLAREKLCWQPQIPLREGLARTWDW 301
>UniRef50_Q9WYX9 Cluster: UDP-glucose 4-epimerase, putative; n=5;
Thermotogaceae|Rep: UDP-glucose 4-epimerase, putative -
Thermotoga maritima
Length = 309
Score = 111 bits (268), Expect = 2e-23
Identities = 104/338 (30%), Positives = 155/338 (45%), Gaps = 50/338 (14%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++GSH V L+E + ++VVDNLS+ ++E L
Sbjct: 3 ILVTGGAGFIGSHVVDKLIE-----NGYGVIVVDNLSSG-------------KVENLNRN 44
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ FY+ I E ++RIF H + V H AA +V SV +P + NI G+ L E
Sbjct: 45 AL-FYEQSIEDEEMMERIFSLHRPEYVFHLAAQASVAISVREPARDAKTNIIGSLVLLEK 103
Query: 125 MRKHGVYKLVYSSS-CTVYGE-PEYLPINES---HPTGKSLTSPYGKSKYFCEEIMKDLC 179
K+GV K ++SS+ +YGE + P E+ HP SPYG +KY E+ +
Sbjct: 104 SIKYGVKKFIFSSTGGAIYGENVKVFPTPETEIPHP-----ISPYGIAKY-STEMYLEFF 157
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+ LRY N G +DP G + + ++ G +E+ +FG
Sbjct: 158 AREYGLKYTVLRYANVYGPR------QDPYGEAGVVAIFTERMLRG--EEVHIFG----- 204
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
DG VRDY++V D+ V+A L + G N N+GTG G +V ++ +G
Sbjct: 205 -DGEYVRDYVYVDDV----VRANLLAMEKGDN--EVFNIGTGRGTTVNQLFKLLKEITGY 257
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHD 337
GDV ++ D A LGW SL +
Sbjct: 258 DKEPVYKPPRKGDVRKSILDYTKAKEKLGWEPKVSLEE 295
>UniRef50_Q2FKD1 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=13; Staphylococcus aureus|Rep: NAD-dependent
epimerase/dehydratase family protein - Staphylococcus
aureus (strain USA300)
Length = 326
Score = 111 bits (266), Expect = 4e-23
Identities = 97/347 (27%), Positives = 166/347 (47%), Gaps = 41/347 (11%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VL+TGGAG++GSH V L Q D D + V+DN K E +K + +
Sbjct: 7 VLITGGAGFIGSHLVDDL---QQDYD---VYVLDNYRTG-------KRENIKSLAD---- 49
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
H +++DIR +A+++I + + D VIH AAL +V ESVEKP+ ++N+ T L EI
Sbjct: 50 -DHVFELDIREYDAVEQIMKTYQFDYVIHLAALVSVAESVEKPILSQEINVVATLRLLEI 108
Query: 125 MRKHG--VYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
++K+ + + +++SS VYG+ LP +S + SPY KY+ E + C S
Sbjct: 109 IKKYNNHIKRFIFASSAAVYGDLPDLP--KSDQSLILPLSPYAIDKYYGERTTLNYC-SL 165
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+++FN G + + SG+ + + + K FG DG
Sbjct: 166 YNIPTAVVKFFNVFGPRQDPK--SQYSGVISKMFD-----SFEHNKPFTFFG------DG 212
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
RD+++V D+ VQ+++L + H N+GTGT ++LE+ G
Sbjct: 213 LQTRDFVYVYDV----VQSVRLIMEHKDAIGHGYNIGTGTFTNLLEVYRIIGELYGKSVE 268
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
GD+ + AD++ ++LG+ ++ +D + ++ N
Sbjct: 269 HEFKEARKGDIKHSYADIS-NLKALGFVPKYTVETGLKDYFNFEVDN 314
>UniRef50_A4WHT4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Pyrobaculum arsenaticum DSM 13514|Rep: NAD-dependent
epimerase/dehydratase - Pyrobaculum arsenaticum (strain
DSM 13514 / JCM 11321)
Length = 299
Score = 110 bits (264), Expect = 6e-23
Identities = 109/339 (32%), Positives = 152/339 (44%), Gaps = 51/339 (15%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
++VTGGAG++GSH L R D +V VD+L A + L
Sbjct: 3 IVVTGGAGFIGSHVAAHLKSRGFD-----VVAVDSLERA------------SGLGRLRAA 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V D+R E L R D V+H AA +V ES EKP EY N T + +
Sbjct: 46 GVPLVVADLRRDE-LPRG------DAVVHAAAYISVEESWEKPYEYMWNNAAVTAKVGKE 98
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+ G Y LVY SS VYG P Y PI+E HPT TSPYG SK EE + L + K
Sbjct: 99 ALRMGAY-LVYLSSAAVYGNPVYTPIDEEHPTRP--TSPYGLSKLAGEEALALLQSAGLK 155
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+A+ R FN G ++G +G+ + +I + G L + +FG G
Sbjct: 156 YAV--ARLFNVYGPGQTGPY----AGV---ITKFIERARAG-LPPV-IFG------SGEQ 198
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RD+IHV D+A + ++ + G G N+GTG S+ E+ A +G
Sbjct: 199 TRDFIHVLDVA----RFVETLVEKGAQG--VFNVGTGRAVSIKELAHAVMKLAGIGGEPI 252
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTW 343
GD+ +VA++ A R LGW +L + W
Sbjct: 253 YASPRPGDIAHSVANIKKA-RGLGWEPKITLEEGLAQLW 290
>UniRef50_A3ZYG1 Cluster: Nucleotide sugar epimerase; n=1;
Blastopirellula marina DSM 3645|Rep: Nucleotide sugar
epimerase - Blastopirellula marina DSM 3645
Length = 318
Score = 109 bits (262), Expect = 1e-22
Identities = 96/342 (28%), Positives = 149/342 (43%), Gaps = 31/342 (9%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
A+L+TGGAG++GSH + LL + SD +++ +DN ++ Y ++ AL +
Sbjct: 2 AILITGGAGFIGSHLIERLLVQSSD----DLICLDNFNDYYDPALKRANAALFDDQP--- 54
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
V + D + A++ +F H I V+H A V SV +P Y Q N+ GT L E
Sbjct: 55 -RVTQIEADFCDSNAMESLFTQHQIKSVVHLGAYAGVRVSVAQPQLYQQTNVGGTLNLLE 113
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+R+H V + + +SS TVYG +P E P G SPYG +K E++
Sbjct: 114 TVRRHPVQRFLLASSSTVYGRGAAIPFAEDAPHGVP-ASPYGATKR-AAELLGLTYAELH 171
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
+ ++ LR F+ G R+ D L I A+ + +FG DGT
Sbjct: 172 QTPVVCLRPFSVYGP----RLRPD-------LALTIFAKAIHTGATIPLFG------DGT 214
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RD+ HV D+ G + A+ + G INLG + ++A NA G
Sbjct: 215 IRRDFTHVSDICDGLIAALTAENVIG----ETINLGHSEPIEMRGLIALLENAFGKKANI 270
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
D+ A++ A R L + + RD W
Sbjct: 271 ERLPERPEDLPVTFANLQKAQRLLNYEPQVPIEVGIRDYVAW 312
>UniRef50_A1RW61 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Thermofilum pendens Hrk 5|Rep: NAD-dependent
epimerase/dehydratase - Thermofilum pendens (strain Hrk
5)
Length = 308
Score = 108 bits (260), Expect = 2e-22
Identities = 103/339 (30%), Positives = 150/339 (44%), Gaps = 44/339 (12%)
Query: 7 VTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKTV 66
+TGGAG++G +T L R ++VV+D+ S A E+L
Sbjct: 5 ITGGAGFIGFNTARYLASRG-----FQVVVLDDFSRATVGR-----------EDLEKVGA 48
Query: 67 HFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMR 126
Y+ D+R AEAL R +D VIH AAL V ES E+P EY+ VN+ GT L
Sbjct: 49 EVYEGDVRDAEALRRFLSG--VDAVIHLAALVDVRESEERPEEYWSVNVEGTRALLAEAS 106
Query: 127 KHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWA 186
+ GV K+V++SS VYG+ L E S YG +K EE+ + S +
Sbjct: 107 RAGVRKVVFASSAAVYGDLGGLTAGEE--VDARPKSFYGLTKRVGEELCR--FFSGRGVV 162
Query: 187 IISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVR 246
++LR FN G E R G + + +V G +KV+G DG R
Sbjct: 163 CVALRIFNVYG--EYSRRGV--------IYEFARRVLSG--LPVKVYG------DGNQTR 204
Query: 247 DYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXX 306
D+++V D+A +A + GF N+ +G SV E+V F +G
Sbjct: 205 DFVYVGDVA----RAFEAVIAEWSGGFEVFNVASGRCVSVNELVRLFEQVTGKRVGVLRE 260
Query: 307 XXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
++ + A A R LG+RA+ SL + R W
Sbjct: 261 PARPEEIRRSCASTEKAARMLGFRASTSLEEGVRRVVEW 299
>UniRef50_Q67KU6 Cluster: UDP-glucose 4-epimerase; n=1;
Symbiobacterium thermophilum|Rep: UDP-glucose
4-epimerase - Symbiobacterium thermophilum
Length = 321
Score = 107 bits (257), Expect = 4e-22
Identities = 98/340 (28%), Positives = 143/340 (42%), Gaps = 37/340 (10%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R VL+TGGAG+VGSH V L + L +VVVDNL+ + E
Sbjct: 6 RTVLITGGAGFVGSHVVERFL-----AEGLRVVVVDNLTTG--------------VREHV 46
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
F+ +DI E + D ++H AA +V SV P+ VN+ GT +
Sbjct: 47 PPGAEFHNIDILTPE-FTSLVGKVKPDTIVHLAAQVSVAVSVRDPVLDADVNVGGTLRVL 105
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
E R+H V V+SSS VYG P LP+ E P S SPYG +K E ++ C
Sbjct: 106 EAAREHQVPNFVFSSSAAVYGIPSSLPVTEDAPF--SPLSPYGIAKVAAEGYIRAYCFLH 163
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
A++ +RY N G + G+ G+ N + A+ R FG DG
Sbjct: 164 GLKAVV-MRYSNVFGPRQKA-AGD--GGVVANFVE-----AILRGHPPVFFG------DG 208
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
RD+I+V D+A ++AI + G + + +N+ +G S+ +
Sbjct: 209 GQTRDFIYVKDVADATLKAIDYLDKSGTSEYLVVNISSGVETSLRTLYTLLCELVKQAPE 268
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDT 342
GD+ + D A LGW SL +T
Sbjct: 269 PILTPPREGDIRHSCLDNRKAREYLGWLPGYSLEQGILET 308
>UniRef50_A5GEM5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Geobacter uraniumreducens Rf4|Rep: NAD-dependent
epimerase/dehydratase - Geobacter uraniumreducens Rf4
Length = 309
Score = 107 bits (257), Expect = 4e-22
Identities = 102/343 (29%), Positives = 161/343 (46%), Gaps = 47/343 (13%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTGGAG++GS+ V LL+ DG E+ V+DNL + Y + PE ++
Sbjct: 4 LVTGGAGFIGSNLVKQLLK---DGH--EVTVLDNLLSGYRSNIATFPEVCLIEGDI---- 54
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+ D+ AEA+ ++ V H AA S++ P+ ++N+ GT + E
Sbjct: 55 ----RDDVVVAEAMK------GVEVVFHLAASVGNKRSIDHPILDAEINVIGTLKILEAA 104
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK- 184
RK G+ K+V SSS ++GE + LPI E HP SPYG +K C M+ C+S K
Sbjct: 105 RKFGIRKIVASSSAGIFGELKTLPIKEDHPVEPD--SPYGSTK-LC---MEKECLSYAKL 158
Query: 185 --WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ LRYFN G ++ D G N++P + + R + L +FG DG
Sbjct: 159 YDLEAVCLRYFNVYGLNQR----FDAYG---NVIPIFAYKML-RGEPLTIFG------DG 204
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
RD++ V D+ +++A G +G A N+ +G+ ++ +V S AS
Sbjct: 205 EQTRDFLDVRDVVQANIKAAMTL---GVSG--AFNIASGSRITINRLVELLSAASAINPL 259
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV ++AD+ A + + +L D R+ W
Sbjct: 260 VQHGPPRPGDVMHSLADIRAAHEAFDFTPEINLEDGLREYMVW 302
>UniRef50_A0RWB8 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=1; Cenarchaeum symbiosum|Rep:
Nucleoside-diphosphate-sugar epimerase - Cenarchaeum
symbiosum
Length = 299
Score = 107 bits (256), Expect = 6e-22
Identities = 104/334 (31%), Positives = 159/334 (47%), Gaps = 49/334 (14%)
Query: 7 VTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKTV 66
VTGGAG++G H LL+R + V+D+ ++A EG V
Sbjct: 5 VTGGAGFIGGHIARHLLDRGHS-----VTVIDS-NDAVDLEGR----------------V 42
Query: 67 HFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMR 126
++ DIR A AL R + D V H AAL +V ES Y+QVN+NGT +
Sbjct: 43 ELHRADIRDAAALRRALDG--TDGVFHQAALVSVQESFSNQELYHQVNVNGTENVLAASL 100
Query: 127 KHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWA 186
G+ K V++SS ++YG+ LPI E + + +PYG++K E++ D S
Sbjct: 101 DLGI-KTVWASSSSIYGDATSLPIGED--SVRDPVTPYGETKAQ-GEVLADKYASMGA-R 155
Query: 187 IISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVR 246
I+SLRYFN G +S +G+ + + +++ G K +FGD G+ R
Sbjct: 156 IVSLRYFNVYGRGQSAAY----AGV---ITGFYNRIESG--KPPVIFGD------GSHTR 200
Query: 247 DYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXX 306
DY+HV D+A ++ A++ P + +IN+GTG SVLE+ SG
Sbjct: 201 DYVHVEDVARANLMAME---SPADSC--SINIGTGIETSVLELARMMIKLSGADLEPEFA 255
Query: 307 XXXXGDVTANVADVALATRSLGWRATRSLHDMCR 340
+V + AD ALA + +GW + L + R
Sbjct: 256 DPPGDEVAFSRADTALARQLIGWSHSIELEEGLR 289
>UniRef50_Q9K6S7 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus
halodurans|Rep: UDP-glucose 4-epimerase - Bacillus
halodurans
Length = 311
Score = 106 bits (255), Expect = 8e-22
Identities = 69/172 (40%), Positives = 91/172 (52%), Gaps = 21/172 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGGAG++GSH V L+ + E+V+VDNLS+ +LK + +
Sbjct: 4 VLVTGGAGFIGSHLVDLLI-----AEGTEVVIVDNLSSG----------SLKHVHPSS-- 46
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
H +K+DI D E+ +ID ++H AA VG SV P QVNI GT L E
Sbjct: 47 --HLFKLDILDERVADVFQEHPDIDRIVHLAAQSKVGPSVLNPTYDAQVNIQGTIRLLEF 104
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMK 176
RK+GV + V++SS +YG LPI E P SPYG SKY E +K
Sbjct: 105 SRKYGVKQFVFASSAAIYGPSHTLPIREEFPA--LPLSPYGTSKYAAEAYVK 154
>UniRef50_O67354 Cluster: Nucleotide sugar epimerase; n=4;
Bacteria|Rep: Nucleotide sugar epimerase - Aquifex
aeolicus
Length = 321
Score = 106 bits (255), Expect = 8e-22
Identities = 98/343 (28%), Positives = 150/343 (43%), Gaps = 39/343 (11%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAE-GEKKPEALKRIEELTG 63
+LVTG AG +G LLE ++ VDNL++ Y E + E LK+ E
Sbjct: 3 ILVTGCAGLIGWKVSEKLLEHGH-----RVIGVDNLNSYYDPRLKEYRLEQLKKFENFK- 56
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
FYKV+I EAL +F+ D VI+ AA V S++ P Y+ N G L E
Sbjct: 57 ----FYKVNIENREALRILFQEFEFDAVINEAARAGVRYSIQNPHIYFTTNTLGNLNLLE 112
Query: 124 IMRKHGVYKLVYSSSCTVY-GEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
+M++ GV KL+ +S+ ++Y G+P +P E P + SPY SK E+
Sbjct: 113 LMKEFGVKKLILASTSSLYAGQP--MPFKEELPVNTPI-SPYAASKK-AAEVTAYTYHYL 168
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
++ LRYF G G + N + + + + KV+G DG
Sbjct: 169 YGIDVVILRYFTVYGL-----AGRPDMAVFNFIYKTLKGIPI------KVYG------DG 211
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
+ RD+ +V D+A V+A+ L G+ IN+G ++ E++ +G
Sbjct: 212 SQKRDFTYVDDVAEATVKALNL------KGYEIINVGNNKPRALKELIELIEKYTGKEVK 265
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
D+ AD+ A R LGW SL + + T W
Sbjct: 266 VEYGDFHKADMRDTWADITKAKRLLGWEPKTSLEEGVKKTVEW 308
>UniRef50_Q1V1Y0 Cluster: UDPglucose 4-epimerase; n=2; Candidatus
Pelagibacter ubique|Rep: UDPglucose 4-epimerase -
Candidatus Pelagibacter ubique HTCC1002
Length = 318
Score = 106 bits (254), Expect = 1e-21
Identities = 99/329 (30%), Positives = 150/329 (45%), Gaps = 30/329 (9%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R VL+TGGAGY+G+ T L++ + VDNLS K + LT
Sbjct: 2 RKVLITGGAGYIGAATTQLFLKKN-----FLVFAVDNLSTG------------KNL--LT 42
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
K F K D L+ + + I VIH AA ESV P +YYQ N
Sbjct: 43 HKNYLFIKSDYSSNHILN-LLKKEKIQDVIHLAASIDNNESVLNPKKYYQNNFFKLIKFL 101
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPE-YLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
E +K + ++SSS VYGE + + P+ E+ S SPYG SK E +++
Sbjct: 102 ENCKKAKIKNFIFSSSAAVYGEVKTFKPLAENFILTPS--SPYGISKMKGEMLIR----K 155
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKEL-KVFGDDYPTA 240
K + I LRYFN G + ++ +L+ ++++ R K + K+ G +Y T
Sbjct: 156 KKYFNSIILRYFNVAGPTFDNKFRQNFKSY-KHLLKKLNEINFSRNKNIFKINGKNYDTI 214
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFH-AINLGTGTGYSVLEMVAAFSNASGX 299
DGT VRD++HV D+A + +++ + N + +N G+G SVL++V F S
Sbjct: 215 DGTCVRDFVHVQDIANINYRSLISIKKILKNDYSLTLNCGSGKENSVLQIVKKFKIISKK 274
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLG 328
GD ++D L + LG
Sbjct: 275 NFKIIFTKPRIGDPPFLLSDNRLFKKKLG 303
>UniRef50_A0B5G2 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Methanomicrobia|Rep: NAD-dependent epimerase/dehydratase
- Methanosaeta thermophila (strain DSM 6194 / PT)
(Methanothrixthermophila (strain DSM 6194 / PT))
Length = 310
Score = 106 bits (254), Expect = 1e-21
Identities = 101/337 (29%), Positives = 158/337 (46%), Gaps = 41/337 (12%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL 61
++ + VTGGAG++GS+ V L + ++ V+DN+S + E L+ +E
Sbjct: 3 NKKIAVTGGAGFIGSNIVRALCDEN------DVTVIDNMSTG-------RRENLRGLE-- 47
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
G+ + F + DI + L R FE+ +D V+H AAL +V S+ P+ + NI+GT ++
Sbjct: 48 -GR-IRFVECDINDIKMLKREFES--VDYVLHQAALPSVQRSIMDPMATNRSNIDGTLSV 103
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
GV ++V++SS VYG+ LP ES SPY +K E + +
Sbjct: 104 LVAAMDCGVKRVVFASSSAVYGDSPELPKRES--LIPRPMSPYAVTKLVGEHYCR-VFYE 160
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDDYPTA 240
+SLRYFN G G+DP+ ++P +I V G + V+G
Sbjct: 161 IYGIECVSLRYFNVFGP------GQDPASEYAAVIPKFIDAVLSG--SQPVVYG------ 206
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DG RD+++V D+ ++ A PG G AIN+GTG S+ ++ A
Sbjct: 207 DGEQTRDFVYVDDVVRANILACL---SPGAPGL-AINIGTGYATSLNRLLDAIGRVLKRY 262
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHD 337
GDV +VAD+ LA LG+ L D
Sbjct: 263 IHPIYTEPRPGDVRDSVADITLAREVLGYAPEYGLED 299
>UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5;
Halobacteriaceae|Rep: UDP-glucose 4-epimerase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 334
Score = 104 bits (249), Expect = 4e-21
Identities = 85/280 (30%), Positives = 141/280 (50%), Gaps = 38/280 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAE-GEKKPEALKRIEELTG 63
+LVTGGAG++G H L ++ D ++VV+DN Y + + +A + +
Sbjct: 9 ILVTGGAGFIGGH-----LAQRFAADGHDVVVLDNRDPFYDLDIKQHNVDAGQEAARNSD 63
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
+ F + D+R AE + + + D V H AA V SV+ P +Y +VN+NGT L +
Sbjct: 64 GSYEFIEGDVRDAELVTDLVAD--ADYVYHQAAQAGVRPSVKNPRKYDEVNVNGTLNLLD 121
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
R G+ + V +SS +VYG+P+YLP +E HPT + SPYG SK E + C +
Sbjct: 122 ACRDEGIERFVMASSSSVYGKPQYLPYDEQHPT--TPVSPYGASKLAAE---RYACAYSE 176
Query: 184 KW--AIISLRYFNPVGAHESGRIGEDPSGIPN-NLMPYISQVAVGRLKELKVFGDDYPTA 240
+ + ++LRYF G P PN + ++S+ G + ++G
Sbjct: 177 VYDLSTVALRYFTVYG----------PRMRPNMAISNFVSRCHNG--EPPVIYG------ 218
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGT 280
DGT RD+ ++ D+ + + L H+ +G A+N+G+
Sbjct: 219 DGTQTRDFTYIEDVIDAN---MTLLHEDAADG-KAVNIGS 254
>UniRef50_Q8U032 Cluster: NDP-sugar dehydratase or epimerase; n=5;
Euryarchaeota|Rep: NDP-sugar dehydratase or epimerase -
Pyrococcus furiosus
Length = 307
Score = 103 bits (247), Expect = 7e-21
Identities = 101/346 (29%), Positives = 158/346 (45%), Gaps = 50/346 (14%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL 61
++ V+VTGGAG++GSH L+E E++V+DNL Y + E P+ K
Sbjct: 3 NKLVVVTGGAGFIGSHIAEALVEEN------EVIVIDNL---YSGKIENIPQGAK----- 48
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
F + DIR ++ I D V H AA +V ESV P+ +VN+ GT +
Sbjct: 49 ------FIEADIRDYSSIAEII--READYVFHEAAQISVEESVRDPIFTDEVNVIGTLNI 100
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
+ + G K++++SS VYGE + LP+ E + K + SPYG SK E ++ V
Sbjct: 101 LKAL-SEGSGKIIFASSAAVYGENKNLPLKEDY-LPKPI-SPYGVSKLAGEHYVR---VF 154
Query: 182 DKKWAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+ + + + LRYFN G +S S N + + + L +FG
Sbjct: 155 YELYGVPGVILRYFNVYGPRQSSAYAGVISIFMKNAL---------KNEPLVIFG----- 200
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
DG RD+I+V D+ VQA L + N+ TG S+LE+ + +
Sbjct: 201 -DGKQTRDFIYVKDV----VQANLLVAEKERANGKIFNVATGKETSILELALKIIDLTSS 255
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GD+ +VAD+ R LG+ + SL + ++T W
Sbjct: 256 SSQILFAPERPGDIKRSVADIN-EIRKLGFEPSYSLEEGLKETLEW 300
>UniRef50_A7DQX9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
NAD-dependent epimerase/dehydratase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 308
Score = 103 bits (247), Expect = 7e-21
Identities = 93/335 (27%), Positives = 146/335 (43%), Gaps = 43/335 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++G H + + ++ E+++ +N SN+ K I L
Sbjct: 3 ILVTGGAGFIGRHLIKKINKKH------ELIIFENFSNS----------DEKNISYLLND 46
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
K D+ ++ N+D VIH AA + +S+E P + +++N+ G+ L
Sbjct: 47 KTKLVKGDLTDFSLINSSLS--NVDLVIHLAAKIDILQSIEHPDQTHKINVEGSLNLLRA 104
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
K+ V + +SS VYG P+ +P+ E T + SPYG K E ++ C
Sbjct: 105 CVKNNVKNFIAASSAAVYGNPKQIPVTEF--TIPNPVSPYGADKIALEFYLRAFC---NA 159
Query: 185 WAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ I I+LR+FN G +S +G+ + I Q K L++FG DG
Sbjct: 160 YGINGIALRFFNVYGLGQSNAY----AGVITKFLNQIHQT-----KPLRIFG------DG 204
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
RD+IH+ DL G Q+I + G G NL +G SV E+ S
Sbjct: 205 KNTRDFIHIDDLVMGIEQSIS--NISGKRG-SVYNLASGKSVSVKELAKLMLEISDKKLE 261
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHD 337
GD+ + A + LA L + SL D
Sbjct: 262 IKYESPRKGDLLYSSASIDLAKNDLSFVPKISLKD 296
>UniRef50_Q1K169 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep: NAD-dependent
epimerase/dehydratase - Desulfuromonas acetoxidans DSM
684
Length = 310
Score = 103 bits (246), Expect = 9e-21
Identities = 88/346 (25%), Positives = 151/346 (43%), Gaps = 38/346 (10%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+++TGGAG++GSH LL++ + V+DN S + P + +
Sbjct: 3 IIITGGAGFIGSHLTEMLLDQGHS-----VTVIDNFSTG---KRSNLPGSSNHL------ 48
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
TVH ++DI E + + D ++H AA+ +V SVE P E + +N++GT + E+
Sbjct: 49 TVH--ELDICNFEGV--LNHTKGADAIVHLAAIASVQASVEAPRETHAINLDGTINMLEV 104
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
R H + V++SS +YG + LP+ E P +PY K E + C K
Sbjct: 105 ARIHDISTFVFASSAAIYGNNQQLPLKEDTPPAP--LTPYAVDKLGSEYYIDFYC-RQFK 161
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+ R+FN G +DPS + ++ + A + + VFGD + D
Sbjct: 162 LKTTTFRFFNVYGPR------QDPSSPYSGVISILMDRAQNK-RPFTVFGDGLQSRDFIF 214
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
V+D + + AA QA P N INLG G ++LE+++ + S
Sbjct: 215 VKDLVEILCKAATQ-QA------PSGN---TINLGNGIQTTLLELLSTVESLSNHKLDTS 264
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANP 350
GD+ + AD + + ++ + + W ++E P
Sbjct: 265 FEEPRPGDIKHSCADNTRLRQLFSYTPKTNIAEGLKQIWDYEELTP 310
>UniRef50_Q11WU7 Cluster: UDP-galactose-4-epimerase; n=1; Cytophaga
hutchinsonii ATCC 33406|Rep: UDP-galactose-4-epimerase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 319
Score = 102 bits (245), Expect = 1e-20
Identities = 93/348 (26%), Positives = 167/348 (47%), Gaps = 34/348 (9%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIV-VVDNLSNAYCAEGEKKPEALKRIEEL 61
+ +L+TGGAG++GS+ LL R SD +E+V V+DN S Y E L
Sbjct: 2 KRILITGGAGFIGSNLTEALLNR-SD---VELVRVLDNFSTGYQHNIH---------EFL 48
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
T F + DIR E + + E I+ + H AAL +V S++ P+ N+ G+ +
Sbjct: 49 THPKYEFVEGDIRNYEDVVKAVEG--IEVISHQAALGSVPRSLKDPMTSNNANVLGSMNV 106
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
F ++ G ++VY+SS +VYG+ P E G L SPY SK E K +
Sbjct: 107 FHAAKESGADRVVYASSSSVYGDDPGSP-KEEDRLGNVL-SPYAASKRSIELYAKAFS-N 163
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ I++RYFN G ++ + G + IP +I+ + G ++ +FG D
Sbjct: 164 VYPFRFIAMRYFNVFGPRQNAQ-GAYAAVIPQ----FITALLNG--QQATIFG------D 210
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
G+ RD+ + ++ +++A+ + FN ++ N+ G+ S+ + A + +G
Sbjct: 211 GSQTRDFTFIDNVLQMNIKALSTDNADAFNRYY--NVACGSTTSLNRVYAILAGCAGSDI 268
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
GD+ ++A+++LA + +G++ + + T+ W + N
Sbjct: 269 KPHYTDPRQGDIKDSLANISLAQKHIGYKPEIQIEEGLIKTFDWFKKN 316
>UniRef50_Q8PXQ4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=3;
Methanomicrobia|Rep: UDP-N-acetylglucosamine 4-epimerase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 334
Score = 102 bits (245), Expect = 1e-20
Identities = 90/325 (27%), Positives = 144/325 (44%), Gaps = 34/325 (10%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+++TGGAG++GSH L + DG EIV+VDNL Y + +KK + L
Sbjct: 4 IVITGGAGFIGSHIAENLAK---DGH--EIVIVDNLDPYYSVDLKKKNLNIA----LNSG 54
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F D+ + + ++ +D V H AA V SVE P + VN++GT + +
Sbjct: 55 DATFINADVTDLSGIKDVIDS-TVDYVYHEAAQAGVRISVEDPFKPNDVNVHGTLNVLKA 113
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
GV K++ +SS +VYG+ +YLP +E HPT SPYG SK E + +
Sbjct: 114 SLDAGVKKVINASSSSVYGKVKYLPFDEQHPT--EPVSPYGVSKLAAEHYCR-VFYEVYG 170
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
SLRYF G P P+ + ++ + + + VFG DG
Sbjct: 171 LPTTSLRYFTVYG----------PRMRPDLAISIFTRKMLAN-EPITVFG------DGEQ 213
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RD+ ++ D+ + +L + +G +N+G G SV ++ +G
Sbjct: 214 TRDFTYIEDVVEANK---RLLYNRATDG-KVLNIGGGNRISVNNLIENLRFITGSTSEII 269
Query: 305 XXXXXXGDVTANVADVALATRSLGW 329
GD +A+V L +G+
Sbjct: 270 NADKQKGDTEDTLANVDLGNNMIGY 294
>UniRef50_A6T0C0 Cluster: UDP-glucose 4-epimerase; n=1;
Janthinobacterium sp. Marseille|Rep: UDP-glucose
4-epimerase - Janthinobacterium sp. (strain Marseille)
(Minibacterium massiliensis)
Length = 325
Score = 102 bits (244), Expect = 2e-20
Identities = 97/348 (27%), Positives = 155/348 (44%), Gaps = 38/348 (10%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+++LVTGGAG++GSH V LL+ + E+VV+DNL + + AL T
Sbjct: 10 QSILVTGGAGFIGSHLVDGLLKEGAR----EVVVIDNL---FVGSEDNLNSALA-----T 57
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
GK V FY+ D + +LD IF+NH ID V + A KA+ S P + N+ L
Sbjct: 58 GKVV-FYRDDAELSTSLDYIFKNHQIDVVFN-CATKALNYSFLNPANAFSTNVTVVLNLL 115
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
EI R+ G L + S+ VYG Y P++E+HP K+ T+ Y K + ++
Sbjct: 116 EIQRRGGFKTLCHFSTSEVYGSAVYEPMDEAHP--KNPTTTYAAGKAAADHAVESYVRMF 173
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYIS-QVAVGRLKELKVFGDDYPTAD 241
A I +R FN G ++ + G+ ++P + ++ G EL D
Sbjct: 174 DLDAFI-VRPFNNYGPRQNYK------GMLAGIIPITAWRILNGIAPELH--------GD 218
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
G RD+I+V D +KL+ + ++N+ T S+ E++ + G
Sbjct: 219 GLQSRDFIYVHDTVDA---VVKLYDK--MPAGESVNISTDNQISISELLPRICSGMGYAG 273
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
DV ++A + ++ T RDT W +AN
Sbjct: 274 EIVKKPGRKSDVLCHLASNEKVHGMIDYKLT-PFDQGLRDTLAWYKAN 320
>UniRef50_Q832Q5 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=6; Lactobacillales|Rep: NAD-dependent
epimerase/dehydratase family protein - Enterococcus
faecalis (Streptococcus faecalis)
Length = 324
Score = 101 bits (242), Expect = 3e-20
Identities = 87/336 (25%), Positives = 163/336 (48%), Gaps = 38/336 (11%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R L+TGGAG++GS TL S + ++VV+D+LS + E L E +T
Sbjct: 5 RNFLITGGAGFIGS----TLANYYSKDN--QVVVIDDLSMG-------QTENLNASENIT 51
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
F + + + ++++ + + D + H AA+ +V +SV +P+E +QVN L
Sbjct: 52 -----FIEGSVTDQQLMEKVLQEYQFDYIFHLAAIASVADSVARPVETHQVNFESVLQLL 106
Query: 123 EIMRKH--GVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC- 179
E++RK+ + +LV++SS VYG+ LP E + LT PY K+ E+ + + C
Sbjct: 107 ELIRKYQKDLKRLVFASSAAVYGDEPTLPKQEESVI-RPLT-PYAVDKFASEKYVLNYCH 164
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+ D + ++R+FN G +++ SG+ + +M ++ + +FG
Sbjct: 165 LYDVPTS--AVRFFNVYGPNQNP--NSPYSGVISIVMDSYKRLLANQEVTFNIFG----- 215
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
DG RD++ V D+ VQA+ L + N+GTG + E++++ ++
Sbjct: 216 -DGKQSRDFVFVEDV----VQALNLVAHSDQSLGEVYNVGTGKATDLNELISSLNDIMKV 270
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSL 335
GD+ ++AD++ R++G+ S+
Sbjct: 271 TLPVEYKEARAGDIKDSLADIS-KLRAIGYEPKYSI 305
>UniRef50_Q5V6W4 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcula
marismortui|Rep: UDP-glucose 4-epimerase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 309
Score = 101 bits (242), Expect = 3e-20
Identities = 99/333 (29%), Positives = 150/333 (45%), Gaps = 45/333 (13%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R VLVTGG G++GSH L + V+D+ S A P+ + IE
Sbjct: 9 RRVLVTGGGGFIGSHLASALAVDN------HVRVLDDFSTGRRAN---LPDDVTVIEG-- 57
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
D+R E LD E +D V H AA+ +V ES+E+P++ +++N T +F
Sbjct: 58 ---------DVRDRETLDAAIEG--VDVVFHEAAMVSVPESIEQPVDCHELNGTATVNVF 106
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
+ R+ ++V++SS VYG P+ +PI E PT + SPYG KY E+ + +
Sbjct: 107 DCARRQDT-RVVFASSAAVYGVPDDVPIGEDAPTEPN--SPYGFEKYLGEQYAR-FYTEE 162
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ LRYFN G G GE +G+ + ++ Q G + L V G DG
Sbjct: 163 YGLPTVPLRYFNVYGPR--GLDGE-YAGV---IGTFVRQAQAG--EPLTVEG------DG 208
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
T RD++HV D+ V+A L G N+GTG S+ E+ + G
Sbjct: 209 TQTRDFVHVDDV----VRANLLAATTDAIG-RPFNVGTGRSISINELAETVRDVVGTDIA 263
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSL 335
D+ + AD+ A LG+ + L
Sbjct: 264 VEHVPGRANDIQQSEADLGDARELLGYEPSLPL 296
>UniRef50_A6BZU3 Cluster: Putative uncharacterized protein; n=1;
Planctomyces maris DSM 8797|Rep: Putative
uncharacterized protein - Planctomyces maris DSM 8797
Length = 324
Score = 100 bits (240), Expect = 5e-20
Identities = 92/341 (26%), Positives = 154/341 (45%), Gaps = 38/341 (11%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTGGAG++GSH L++ DG + V DNLS AL +E +
Sbjct: 5 LVTGGAGFIGSHLATRLIK---DGH--RVRVFDNLSTG----------ALHNLEHIKDD- 48
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
V F + D+R A+++ ++ V H AAL +V SVE PL+ ++ + GT + +
Sbjct: 49 VEFVQGDLRDLAAVEQA--TAGVEIVFHQAALASVPRSVEHPLDTHEACVTGTVHVLDAA 106
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
R+ GV ++VY+ S + YG E +P +E + SPY +K E+ +
Sbjct: 107 RRSGVQRVVYAGSSSAYGNQEQMPKHEGQT--PEVLSPYAAAK-LAGELYCQAFANSYDL 163
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDDYPTADGTG 244
+ +RYFN G +DP+ + ++P + S + GR +FGD + D T
Sbjct: 164 ETVRIRYFNVFGPR------QDPNSPYSAVIPLFTSALLEGR--RPMIFGDGLQSRDFTF 215
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
V D + ++ A A K+ +G + N G+ ++++++ N
Sbjct: 216 V-DNVVQANILASQAPADKV------SG-NVYNAACGSSLNLIDLLKFICNQLDKPYDPD 267
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV + AD++ A R LG+ + + R T W
Sbjct: 268 FQPARTGDVKHSWADISAAQRDLGYEPVVEIEEGLRKTIDW 308
>UniRef50_A5UZ84 Cluster: NAD-dependent epimerase/dehydratase; n=5;
Chloroflexi (class)|Rep: NAD-dependent
epimerase/dehydratase - Roseiflexus sp. RS-1
Length = 317
Score = 100 bits (240), Expect = 5e-20
Identities = 93/341 (27%), Positives = 150/341 (43%), Gaps = 35/341 (10%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
L+TGGAG++GSH LL R GD ++V +DN ++ Y + +K + R LT
Sbjct: 4 LITGGAGFIGSHLSDALLAR---GD--QVVCIDNFNDYY--DPARKRRNIARA--LTNPG 54
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+ D R A+A+DRIF ++ V H A+ S++ P Y VN+ GT + E
Sbjct: 55 YTLVEADFRDADAMDRIFAHYRPQRVAHIGAMAGPRPSMQNPALYEDVNVRGTLIVLETA 114
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
++ V LV +S+ +VYG P +E PT + L S Y +K E++
Sbjct: 115 ARYQVDGLVLASTSSVYGLSP-TPWSEESPTDRPL-SFYAATKK-AAEVLAYTAHRRHGI 171
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
I +R+F G P G P ++ P++ A+ K + +F G GV
Sbjct: 172 PIRIVRFFTVYG----------PRGRP-DMTPHLFVDAMVAGKAITLFN------GGIGV 214
Query: 246 -RDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RD+ ++ D+ AG + A+ + F NLG + +++ V +G
Sbjct: 215 YRDWTYIADIVAGVIAALDM-----DAAFEIFNLGHSSPVQLIDFVRTLEEVTGLRAGIV 269
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
D A + AT+ LG++ SL + W W
Sbjct: 270 AQPLPAADPPVTFARIDKATQMLGFQPRTSLEEGLARFWEW 310
>UniRef50_Q0YI68 Cluster: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR:3-beta hydroxysteroid
dehydrogenase/isomerase:Polysaccharide biosynthesis
protein CapD:dTDP- 4-dehydrorhamnose
reductase:Nucleotide sugar epimerase; n=3; cellular
organisms|Rep: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR:3-beta hydroxysteroid
dehydrogenase/isomerase:Polysaccharide biosynthesis
protein CapD:dTDP- 4-dehydrorhamnose
reductase:Nucleotide sugar epimerase - Geobacter sp.
FRC-32
Length = 328
Score = 100 bits (239), Expect = 7e-20
Identities = 86/344 (25%), Positives = 149/344 (43%), Gaps = 26/344 (7%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKP-EALKRIEELTG 63
+L+TGGAG++GSH L D I++VDN ++ Y +++ G
Sbjct: 3 ILITGGAGFIGSHLAERLFLCGHD-----IIIVDNFNDFYSPAVKRRNFTETAGNAAACG 57
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
+ + + DIR E + IF D VIH AA V S++ PL Y +VN+ GT L E
Sbjct: 58 RRLLLCEGDIRDEEFIRAIFTQELPDAVIHLAAAAGVRPSIDNPLLYEEVNVRGTMNLLE 117
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+ GV +++SS +VYG +P E+ P + SPY +K E++
Sbjct: 118 AAKAIGVRLFLFASSSSVYGNNPKVPFAEADPVDNPI-SPYAATKK-AGELICHTYHHLY 175
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
I LR+F G + + + ++ + G K + +G DG+
Sbjct: 176 DINIACLRFFTVYGPRQRPDLA---------ISKFVRLIEQG--KPIPFYG------DGS 218
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RDY ++ D+ AG +A++ + G + NLG + ++ +V + G
Sbjct: 219 TSRDYTYIGDIVAGIEKALQ-WVNTGEKRYDIFNLGGSSPVALNRLVKIIEHQLGKKAVL 277
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQE 347
GDV A++ ++ LG++ + + + RW +
Sbjct: 278 ECLPMQAGDVERTFANIEKSSSVLGYKPVTPIEEGIANFVRWYQ 321
>UniRef50_A3HAA1 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Caldivirga maquilingensis IC-167|Rep: NAD-dependent
epimerase/dehydratase - Caldivirga maquilingensis IC-167
Length = 301
Score = 99.5 bits (237), Expect = 1e-19
Identities = 100/337 (29%), Positives = 158/337 (46%), Gaps = 44/337 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPE-ALKRIEELTG 63
V +TGGAG++G +T I L ER +E+VV+D+L E+ E A++R+ +
Sbjct: 3 VPITGGAGFIGHNTAIYLRERG-----VEVVVLDSL--------ERSTEYAVRRLRDAG- 48
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
V + D+ + + + + D VIH AA V ES+++P +Y + N+ GT +
Sbjct: 49 --VSIIRGDVGDSSTVGPLVGDS--DVVIHAAAYIDVHESMQRPADYVRNNVVGTTVVAH 104
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+HG +V+ SS VYG P LPI E HP SPYG SK EE+++
Sbjct: 105 ECLRHG-KPMVFISSAAVYGNPVRLPIPEDHPLRP--ISPYGLSKVLSEEVVRFFGGLGL 161
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
++ I LR FN G ++ S +M +I +V G L + ++G DG
Sbjct: 162 RFVI--LRPFNVYGPGQN-------SAYAGVIMRFIERVKRG-LPPV-IYG------DGN 204
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RD+IHV D+A + I+ + G N+GTG ++++ G
Sbjct: 205 QARDFIHVLDVA----RVIERVITGDYWG-ETFNVGTGVPTRIIDLARLVMGLFGMDGEP 259
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCR 340
GD+ + AD++ A LG+ + SL D R
Sbjct: 260 LFDKPRPGDIRDSYADISKARSILGFTPSISLEDGLR 296
>UniRef50_Q58455 Cluster: Uncharacterized protein MJ1055; n=4;
cellular organisms|Rep: Uncharacterized protein MJ1055 -
Methanococcus jannaschii
Length = 326
Score = 99.5 bits (237), Expect = 1e-19
Identities = 91/342 (26%), Positives = 154/342 (45%), Gaps = 33/342 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAE-GEKKPEALKRIEELTG 63
+LVTG AG++G H L++ D L+++ +DNL+N Y EK+ E LK E T
Sbjct: 6 ILVTGSAGFIGFHLSKYLMDNYED---LKVIGIDNLNNYYNPVLKEKRNEILKNYENYT- 61
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
F K+D + L ++ ID ++H A V S++ P Y + N GT +FE
Sbjct: 62 ----FIKLDFSDWDDLVENLKDKEIDLIVHLGAQAGVRYSLQNPWAYIKSNEMGTLNIFE 117
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
R+ + K+VY+SS +VYG +P +E K + S Y +K E+M +
Sbjct: 118 FARRFDIEKVVYASSSSVYGGNRKIPFSEDDRVDKPI-SLYASTKR-SNELMAHVYHHLY 175
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
+I LR+F G E GR D + + + +G KE++V+ +Y G
Sbjct: 176 GIKMIGLRFFTVYG--EYGR--PDMA-----YFKFAKNILLG--KEIEVY--NY----GN 218
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RD+ ++ D+ G ++AIK F+ + NLG ++ +
Sbjct: 219 MERDFTYISDVVDGILRAIK----KDFD-YEIFNLGNSKPVKLMYFIELIEKYLNKKAKK 273
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV AD++ + + LG++ ++ + + W
Sbjct: 274 KFLPMQDGDVLRTYADLSKSEKLLGYKPKVTIEEGLKRFCNW 315
>UniRef50_Q9K7I2 Cluster: UDP-glucose 4-epimerase; n=17; cellular
organisms|Rep: UDP-glucose 4-epimerase - Bacillus
halodurans
Length = 308
Score = 98.7 bits (235), Expect = 2e-19
Identities = 100/348 (28%), Positives = 156/348 (44%), Gaps = 44/348 (12%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M++ VLVTGGAG++GSH V LL + E+VVVDNL+ + E
Sbjct: 1 MTKKVLVTGGAGFIGSHIVELLLNKG-----YEVVVVDNLTTG-------------QFEN 42
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
++ V FYK DI +E D IF + VIH AA V +S+ P + NI GT
Sbjct: 43 ISSFNVPFYKTDIVSSELKD-IFSKEKPNYVIHHAAQVDVTKSINLPTYDAETNIIGTIN 101
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL-C 179
L ++ V K++Y+SSC VYG+ I E P S YG SK E ++
Sbjct: 102 LLSCCCQYEVDKVIYASSCAVYGDTGDSSITEDFPI--QPISFYGISKSVPEMYIRQFHD 159
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+ K+ I RY N G ++ + GE ++ + A+ R + + ++G
Sbjct: 160 LYGLKYTI--FRYANVYGPRQTSK-GE------GGVISIFTTKALKREQPI-IYG----- 204
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
+G RD+I+V D+A + A+ + G N N+GT S+ E+ +
Sbjct: 205 -NGEQTRDFIYVEDIAKANALALDI----GDN--EIFNIGTNQKTSINELYNKVNVVRPF 257
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQE 347
GD+ + A + LGW+ + SL ++T ++ E
Sbjct: 258 APSAKYTSPREGDILHSRLSYVKAKKILGWKPSVSLERGIQETLKYYE 305
>UniRef50_Q3E561 Cluster: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR:3-beta hydroxysteroid
dehydrogenase/isomerase:Polysaccharide biosynthesis
protein CapD:dTDP- 4-dehydrorhamnose
reductase:NmrA-like:Nucleotide sugar epimerase; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR:3-beta hydroxysteroid
dehydrogenase/isomerase:Polysaccharide biosynthesis
protein CapD:dTDP- 4-dehydrorhamnose
reductase:NmrA-like:Nucleotide sugar epimerase -
Chloroflexus aurantiacus J-10-fl
Length = 337
Score = 98.3 bits (234), Expect = 3e-19
Identities = 102/347 (29%), Positives = 146/347 (42%), Gaps = 43/347 (12%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL 61
++ +LVTGGAG++GS V L +VVVDNL N A + L
Sbjct: 3 AKRILVTGGAGFIGSELVTQLAAAGH-----RVVVVDNLVNGKRAN----------LAHL 47
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
V +VDIR E + R+ + ++ V H A L V S+ P E + VN GT L
Sbjct: 48 ADADVELVEVDIRQREVIARLVQG--VEIVYHLACL-GVRHSLHDPFENHDVNATGTLIL 104
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
++ R+ V + VY SS VYG ++P+ E HPT + YG K E + S
Sbjct: 105 LDLARRADVPRFVYVSSSEVYGTARWVPMTEEHPTYP--MTVYGGGKLAGECYTRAFWES 162
Query: 182 DKKWAIISLRYFNPVG--AHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
++ + +R FN G +H G GE ++P A+ L + +FG
Sbjct: 163 -YRYPTVVVRPFNSFGPRSHHEGDSGE--------VIPKFMLRAMAGL-PMVIFG----- 207
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
DGT RD+ +V D A G + A + G NLG G S+ E+ + G
Sbjct: 208 -DGTQTRDFTYVSDTARGIMLAGMV--DAAIGG--TFNLGQGREISINELARTVATVVGR 262
Query: 300 -XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV AD A LG+ T SL + + W
Sbjct: 263 PDAAIVYDIPRPGDVLRLYADSTRAQHVLGFTPTVSLQEGLQRLQEW 309
>UniRef50_A3ERU6 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=2; Bacteria|Rep: Nucleoside-diphosphate-sugar
epimerase - Leptospirillum sp. Group II UBA
Length = 316
Score = 98.3 bits (234), Expect = 3e-19
Identities = 98/344 (28%), Positives = 155/344 (45%), Gaps = 42/344 (12%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTGGAG++GSH V LLE E+ V+DN S K E L EL+G+
Sbjct: 4 LVTGGAGFIGSHLVRALLENGH-----EVRVLDNFSTG-------KEENLA---ELSGR- 47
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+ + D+R +++ E + V H AA+ +V S+ P + N+NGT L
Sbjct: 48 IDVIRGDVRSFADIEKALEG--VTFVFHQAAVGSVPRSIADPFDTQTANVNGTLNLLWKA 105
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
++ GV ++V + S +VYG+ +P E+ S SPY SK +E+ +
Sbjct: 106 KEFGVQRVVIAGSSSVYGDTPGMPRVET--LLPSPLSPYALSK-LSQELFGKIFSKTFGL 162
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG- 244
++LRYFN G + R E + IP + + + AV T +GTG
Sbjct: 163 DTVTLRYFNIFGPRQDPR-SEYAAVIPRFVRAILKKDAV--------------TINGTGE 207
Query: 245 -VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RD+ + ++ ++ A++ G A N+G G+ +S+LE+V S+ G
Sbjct: 208 QSRDFTFIDNVVQANLLAMETTRGIG----EAFNIGCGSSFSILELVDHLSDILGVRPEV 263
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQE 347
GD A+ AD++ A LG+ + T RW E
Sbjct: 264 RHLPPRAGDPMASQADISKARDLLGYSPKVYFREGLERTARWFE 307
>UniRef50_A2SRX5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Methanocorpusculum labreanum Z|Rep: NAD-dependent
epimerase/dehydratase - Methanocorpusculum labreanum
(strain ATCC 43576 / DSM 4855 / Z)
Length = 307
Score = 97.9 bits (233), Expect = 4e-19
Identities = 87/337 (25%), Positives = 147/337 (43%), Gaps = 41/337 (12%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
L+TGGAG++ SH L+ + D + ++D++S + K I+
Sbjct: 4 LITGGAGFIASHIAEELIRKNHD-----VTLLDDMSAG----------STKNIQP----D 44
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
F K + L I + H+ + + H AA+ +V +S+E PL ++VN GT +
Sbjct: 45 AEFIKGSVTDRPLLAEICKTHSFEGIFHLAAVASVQKSIEDPLLVHEVNATGTLNILNAA 104
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
++HG+ K+V S+S YG+ P E SPY SK E ++
Sbjct: 105 KEHGIRKVVLSASAAAYGDNPVFPKRED--MLPEPLSPYAVSKITAEMYCRNF-ADLFGV 161
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
+LRYFN G +DP+ ++P ++ V K + +FG DG
Sbjct: 162 ETTALRYFNVFGPR------QDPNAEYAAVIPKFTERIVHDKKPV-IFG------DGNQT 208
Query: 246 RDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXX 305
RD++ V D+ ++ A+ H G N+GTG S+ ++ A+G
Sbjct: 209 RDFVFVKDVVLANMLAMN-SHTCG-----TFNIGTGIQTSLNDLAGMIMRAAGISCDIIY 262
Query: 306 XXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDT 342
GD+ +VAD++ A LG+ S+ D ++T
Sbjct: 263 EAPRPGDIRYSVADISKAKPELGYAPKYSIEDGIKET 299
>UniRef50_Q1Q482 Cluster: Similar to dTDP-glucose 4,6-dehydratase;
n=2; Candidatus Kuenenia stuttgartiensis|Rep: Similar to
dTDP-glucose 4,6-dehydratase - Candidatus Kuenenia
stuttgartiensis
Length = 319
Score = 97.1 bits (231), Expect = 6e-19
Identities = 101/328 (30%), Positives = 151/328 (46%), Gaps = 46/328 (14%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++GS+ V L+E +G + VVD+LS EE K
Sbjct: 3 ILVTGGAGFIGSNLVDQLIE---EGH--RVAVVDDLSTGK--------------EENIHK 43
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
FY +DI A++L+ +F+ + V H AA V +SVE P+ +NI G+ L ++
Sbjct: 44 KAEFYNIDICDAKSLEEVFKQIKPEIVNHHAAHANVRKSVETPVYDANINILGSLNLCQL 103
Query: 125 MRKHGVYKLVYSSS-CTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
K+ V K +Y+S+ VYGEP+ LP NES P S YG SK+ E L V K
Sbjct: 104 SNKYRVKKFIYASTGGAVYGEPKQLPANESTP--PEPLSHYGVSKHTVEHY---LHVFHK 158
Query: 184 KW--AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ + LRY N G +S P G ++ S++ + + K+ +FG D
Sbjct: 159 LYDLNVTILRYPNVYGPRQS------PHG-EAGVVAIFSELML-QNKQPTIFG------D 204
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
G+ RDY++V D+ ++ + NG NLG G S +E+ A A
Sbjct: 205 GSKTRDYVYVDDIVKANIAVLGDIG----NG-EIYNLGWGKEISDMEVFLAVRRALRKDI 259
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGW 329
G+V D + A R + W
Sbjct: 260 EPILGQKRHGEVDHISLDHSKARREIKW 287
>UniRef50_A6GLY7 Cluster: Putative uncharacterized protein; n=1;
Limnobacter sp. MED105|Rep: Putative uncharacterized
protein - Limnobacter sp. MED105
Length = 294
Score = 97.1 bits (231), Expect = 6e-19
Identities = 80/313 (25%), Positives = 143/313 (45%), Gaps = 32/313 (10%)
Query: 33 EIVVVDNLSNAYCAEGEKKPEALKRIEELTGKTVHFYKVDIRCAEALDRIFENHNIDCVI 92
+++V+DNLS+ G ++ IE G + DIR ++ +
Sbjct: 11 QVIVLDNLSS-----GRRE-----NIENWLGPNTCLVEGDIRDQSLVENLLAE--TAGAF 58
Query: 93 HFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINE 152
H AAL +V +S+E+P E + +N+ GT L E RK G K+V++SS VYG P++E
Sbjct: 59 HLAALVSVPQSIERPTESFSINLEGTLNLLEASRKQGNKKIVFASSAAVYGNRHSYPVSE 118
Query: 153 SHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIP 212
+ G+ + SPYG K CE+ +L + + +R+FN G +DPS
Sbjct: 119 T-MAGQPI-SPYGLHKLMCEQ-HAELFANLYNVNSVGMRFFNVYGPR------QDPSS-- 167
Query: 213 NNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNG 272
PY +++ + L+ DG+ RD+++V D+ ++A+ Q G
Sbjct: 168 ----PYSGVISI-FIDRLRRGLAPTIYGDGSQTRDFVYVGDVVQALIKAMNSKKQ----G 218
Query: 273 FHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRAT 332
F A N+G G ++ + + G G++ ++A+++ LG++A
Sbjct: 219 FAAYNVGRGESVTINMLWQILCDVVGTNLPAKLGPAREGEIHTSLANISKIEAELGYKAE 278
Query: 333 RSLHDMCRDTWRW 345
+L + T+ W
Sbjct: 279 ITLQEGLIKTYEW 291
>UniRef50_Q65E95 Cluster: Putative uncharacterized protein; n=1;
Bacillus licheniformis ATCC 14580|Rep: Putative
uncharacterized protein - Bacillus licheniformis (strain
DSM 13 / ATCC 14580)
Length = 309
Score = 96.7 bits (230), Expect = 8e-19
Identities = 90/347 (25%), Positives = 147/347 (42%), Gaps = 42/347 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGG G++GSH LL+ + ++DNL+ + + + G
Sbjct: 4 VLVTGGCGFIGSHIAEQLLKEN-----YRVSILDNLTTGHRSN-------------IDGL 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ FY+ DI E +D + ++ + D ++H AA +V ESV L +NI G+ + +
Sbjct: 46 PIDFYEQDITKPEVID-VIKSIDPDYIVHLAAQVSVAESVSDFLNDENINIRGSLHIIKA 104
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+ V K+V++SS VYG P+YLP++ H T SPYG +K E +K L
Sbjct: 105 AGECNVKKIVFASSAAVYGNPDYLPVDTRHQTNPG--SPYGLTKLTVENYLK-LAYDLYG 161
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
LRY N G + + GE G+ + ++ K +FG DG
Sbjct: 162 TEYCILRYSNVYGPRQDAK-GE--GGVVSIFSDLLTSG-----KAPVIFG------DGEQ 207
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RD+I+V D+A +V+A+K +N+ G +V E+ A+
Sbjct: 208 SRDFIYVGDVACANVKALKA------QSNVCLNVSNGFSITVNELFTEMKKATNSELSPI 261
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPN 351
GD+ + + L W L + T + + N
Sbjct: 262 YQDERPGDIRHSTLCNEETKKILNWEPKMPLAEGLEKTISYYKKEMN 308
>UniRef50_Q2JEQ1 Cluster: NAD-dependent epimerase/dehydratase; n=3;
Frankia|Rep: NAD-dependent epimerase/dehydratase -
Frankia sp. (strain CcI3)
Length = 334
Score = 96.7 bits (230), Expect = 8e-19
Identities = 79/261 (30%), Positives = 118/261 (45%), Gaps = 24/261 (9%)
Query: 91 VIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVY-----KLVYSSSCTVYGEP 145
V H AAL V ES P+ Y+Q N+ GT L + + + V+ S+C VYG
Sbjct: 69 VCHLAALTRVRESRLDPVRYFQTNLTGTINLLAALEEGAEHTGVAPAFVFGSTCAVYGNV 128
Query: 146 EYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIG 205
+ I E+ P + +PYG SK+ E ++ + A+I LR FN GA +G I
Sbjct: 129 DLARIPETCPPDPA--NPYGTSKFAAERLLSHQAGTGLLGAVI-LRSFNVAGA-VAGHID 184
Query: 206 EDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLF 265
D S ++P VA G +V G DG +R+Y+HV D+A ++ A+ +
Sbjct: 185 RDGS----RIIPAAIAVASGCRDVFRVNG------DGLALREYVHVVDMATAYLTAL-VA 233
Query: 266 HQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATR 325
+PG N+G+G G SV +++AA +G T + D
Sbjct: 234 ARPGHCA--VFNVGSGVGVSVTDVLAAVGRVAGRPVRRVHCPPVSEPRTL-IGDSTRIRA 290
Query: 326 SLGWRATRSLHD-MCRDTWRW 345
LGW + S D + D WRW
Sbjct: 291 DLGWSSPASSIDRIVADAWRW 311
>UniRef50_Q2S4X1 Cluster: UDP-glucuronate 5'-epimerase; n=3;
Bacteria|Rep: UDP-glucuronate 5'-epimerase -
Salinibacter ruber (strain DSM 13855)
Length = 327
Score = 94.7 bits (225), Expect = 3e-18
Identities = 85/346 (24%), Positives = 147/346 (42%), Gaps = 33/346 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKR--IEELT 62
V+VTGGAG++G+ LL+ +V +DN Y P A+K IE+
Sbjct: 3 VVVTGGAGFIGARLCRRLLKVGHT-----VVAIDNFDPFY-------PRAMKEEGIEDFP 50
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
++ + DI + + ++D VIH AA V S+E P Y Q N+ GT ++
Sbjct: 51 RESFSLVETDICNTGTVLQALHARDVDAVIHLAAKAGVRPSIESPGAYEQANVAGTQSML 110
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
E+ ++ GV ++ SS +VYG E +P +E P + SPY +K E++
Sbjct: 111 EVAQRLGVDTFLFGSSSSVYGNNEKVPFSEEDPVRHPI-SPYAATKR-SGELLAHTFHHL 168
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ LR+F G + + + + Q+ + + ++G DG
Sbjct: 169 YDMTVHCLRFFTVYGPRQRPDLA---------IHKFARQLLTD--QPITMYG------DG 211
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
T RDY +V D+ G ++++ + INLG + ++++ ++A G
Sbjct: 212 TSSRDYTYVDDIVDGVMRSLHRAKSLEAPEYEIINLGGSETTQLKDLISGIADAMGITPE 271
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEA 348
GDV AD++ A LG+ + + W EA
Sbjct: 272 IKQLPEQPGDVERTYADISKAEELLGYEPDTPIQVGLQKFVSWVEA 317
>UniRef50_Q7D561 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=20; Bacteria|Rep: NAD-dependent
epimerase/dehydratase family protein - Mycobacterium
tuberculosis
Length = 322
Score = 94.7 bits (225), Expect = 3e-18
Identities = 101/339 (29%), Positives = 142/339 (41%), Gaps = 40/339 (11%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTG AG++GS V LL +DG +V +DN + +E L +
Sbjct: 12 LVTGAAGFIGSTLVDRLL---ADGH--SVVGLDNFATGRATN----------LEHLADNS 56
Query: 66 VH-FYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
H F + DI A+ L I E H + V H AA V SV P VN+ GT L E
Sbjct: 57 AHVFVEADIVTAD-LHAILEQHRPEVVFHLAAQIDVRRSVADPQFDAAVNVIGTVRLAEA 115
Query: 125 MRKHGVYKLVYSSS-CTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
R+ GV K+V++SS ++YG P P E+ PT + SPY K E + +
Sbjct: 116 ARQTGVRKIVHTSSGGSIYGTPPEYPTPETAPTDPA--SPYAAGKVAGEIYLNTF----R 169
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
+ + P + +DP G + + + G K +VFG DGT
Sbjct: 170 HLYGLDCSHIAPANVYGP---RQDPHGEAGVVAIFAQALLSG--KPTRVFG------DGT 218
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RDY+ V D+ V+ G N+GTG S ++ +A + A G
Sbjct: 219 NTRDYVFVDDVVDAFVRV-----SADVGGGLRFNIGTGKETSDRQLHSAVAAAVGGPDDP 273
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDT 342
GD+ + D+ LA R LGWR L D R T
Sbjct: 274 EFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADGVRRT 312
>UniRef50_Q2FN70 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=1; Methanospirillum hungatei JF-1|Rep:
NAD-dependent epimerase/dehydratase precursor -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 313
Score = 94.7 bits (225), Expect = 3e-18
Identities = 95/346 (27%), Positives = 154/346 (44%), Gaps = 40/346 (11%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
MS+ LVTGGAG++GSH L R GD ++++D+L + L I +
Sbjct: 1 MSKRYLVTGGAGFIGSHLSQALAAR---GD--RVIILDSLDSG----------KLCNISD 45
Query: 61 LTGKT-VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTC 119
L V F + I L + + ID + H AAL +V S++ P +++NI+G
Sbjct: 46 LLEDDHVEFIEDTILNGSRLVSLC--NGIDGIFHLAALVSVQRSIDDPRLNHRINIDGLF 103
Query: 120 TLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC 179
+FE R V K+V +SS +YG +YLP ++ L SPY K E+ +
Sbjct: 104 EVFEAARLARVPKIVLASSAALYGN-DYLPPHKETFASVPL-SPYAVGKCL-SELYAAVY 160
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+ LR+FN G +DPS + ++ A+ R +FG
Sbjct: 161 TDLYGVHSVCLRFFNVYGPK------QDPSSPYSGVISKFMD-AISRDDGFTIFG----- 208
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
DG RD+++V D+ VQA+ L + +G N+GTG S+ + SG
Sbjct: 209 -DGEQTRDFVYVLDV----VQALILSMEKSVSG--VFNVGTGASVSINHLARTIMEVSGK 261
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
G+V + AD++ + +G++ SL + +T+ W
Sbjct: 262 KVGIRYLDARDGEVRHSCADISKISDGMGYKPGYSLIEGLSETYSW 307
>UniRef50_Q8THP9 Cluster: DTDP-glucose 4,6-dehydratase; n=3;
Methanosarcina|Rep: DTDP-glucose 4,6-dehydratase -
Methanosarcina acetivorans
Length = 298
Score = 94.3 bits (224), Expect = 4e-18
Identities = 90/319 (28%), Positives = 142/319 (44%), Gaps = 45/319 (14%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VL+TGGAG++GSH E + ++DNL+ + P+ +
Sbjct: 3 VLITGGAGFIGSHIAEYFAEAGH-----SVRILDNLTTGF---SRNIPQ---------HR 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V F + DI ++++ +DCV H AAL +V S EKP+E +++N GT + +
Sbjct: 46 NVEFIQGDICDPSSVEKAVS--GMDCVFHEAALVSVPLSCEKPVEAFRINTLGTLNVLQA 103
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINES-HPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+ GV K V +SS VYG LP E+ +P SPY SK E + + + +
Sbjct: 104 CVRAGVEKFVTASSAAVYGNNPELPKRENMYP---EPASPYAISKLDGEYLAR-MFYEEH 159
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDDYPTADG 242
LRYFN G +DP ++P ++ + G K+L ++G DG
Sbjct: 160 GLRTTCLRYFNVYGPR------QDPKSPYAAVIPIFLERAKAG--KDLVIYG------DG 205
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
RD++HV D+ +V A++ H G N+ G +VLE+ +G
Sbjct: 206 LQSRDFVHVKDVVMANVAALE--HGDG----QVFNVAMGKSVTVLELAENIIELTGSSSQ 259
Query: 303 XXXXXXXXGDVTANVADVA 321
GDV + ADV+
Sbjct: 260 IIHAESRAGDVRDSRADVS 278
>UniRef50_Q5KWG9 Cluster: Nucleotide sugar epimerase; n=1;
Geobacillus kaustophilus|Rep: Nucleotide sugar epimerase
- Geobacillus kaustophilus
Length = 314
Score = 93.5 bits (222), Expect = 8e-18
Identities = 91/342 (26%), Positives = 145/342 (42%), Gaps = 37/342 (10%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
++VTGGAG++GSH L E+ E+ +D Y E +++ + LTG
Sbjct: 3 IVVTGGAGFIGSHLAARLHEQGH-----EVAAIDCFHPYYPVERKER-----QFHALTGG 52
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V + D+ EA R F D V H AAL V S+ PL Y +I T +
Sbjct: 53 RVPLARFDLLDGEATKRWFSQFRPDVVYHLAALPGVPYSLAHPLAYIDYDIKATVNVLAA 112
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+ GV ++++SS +VYG+ +P+ E G+ + SPY +KY E
Sbjct: 113 AGEAGVAHVLFASSSSVYGDRGNVPLREEMADGR-VVSPYAAAKYGAESFC-HAYAHLYG 170
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLM-PYISQVAVGRLKELKVFGDDYPTADGT 243
+ + RYF G P G P+ + ++ ++ G +E+ V+G GT
Sbjct: 171 YQMTIFRYFTVYG----------PWGRPDMAIGTFLRRLLAG--EEIVVYG------KGT 212
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RDY ++ D+ G + A+ H+ G NLG G + +E + A
Sbjct: 213 -ARDYTYIDDIVEGMIAAL---HRSGGRS-EVFNLGAGAPVT-MEQLLAELRKHFPDLKI 266
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV A AD+ A R+ G++ + + T W
Sbjct: 267 VHAPERKGDVKATWADITKAERAFGYKPKVAFAEGLARTVAW 308
>UniRef50_Q7P6D7 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=1;
Fusobacterium nucleatum subsp. vincentii ATCC 49256|Rep:
UDP-N-acetylglucosamine 4-epimerase - Fusobacterium
nucleatum subsp. vincentii ATCC 49256
Length = 345
Score = 93.1 bits (221), Expect = 1e-17
Identities = 92/358 (25%), Positives = 155/358 (43%), Gaps = 36/358 (10%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQ------SDGDP---LEIVVVDNLSNAYCAEGEKK--- 51
+VL+TGGAG++GSH V L+ + + DP ++I +++ L +A E +K
Sbjct: 2 SVLITGGAGFIGSHLVEKFLKEKHKVIVVDNFDPFYSMDIKILNVLESANKKELREKILD 61
Query: 52 ---PEALKRIEELT-GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKP 107
E L + + T Y DI E L IF NID VI+ AAL V SV +P
Sbjct: 62 LGDDEKLNFLVKYTESDNYKLYVEDICNLENLKEIFIKENIDFVINLAALAGVRPSVLRP 121
Query: 108 LEYYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKS 167
+Y +VNI G + EI ++ + KL+ +SS ++YG + E + SPY +
Sbjct: 122 FDYERVNIKGFLNILEICKEFKINKLIQASSSSIYGNSKADIFTEDIRVDFPI-SPYAAT 180
Query: 168 KYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRL 227
K EE + +I LR+F G + + + ++ ++
Sbjct: 181 KKAGEE-FGSVYSHLYNIDMIQLRFFTVYGERQRPDLA---------IHKFVKKIE--ND 228
Query: 228 KELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVL 287
+E+ ++G DG RDY ++ D+ G ++ + + N + INLG+ ++L
Sbjct: 229 EEITIYG------DGNTSRDYTYIKDIIDGIFKSFEYLNNHQ-NVYEIINLGSSRKINLL 281
Query: 288 EMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
+MV N GDV A + A + L ++ + D + W
Sbjct: 282 DMVKIIENKLNKKAKLKFIDKQAGDVDKTFACIDKAEKILNYKVSTKFEDGIENFVNW 339
>UniRef50_Q2MFK2 Cluster: Putative apramycin biosynthetic
oxidoreductase 1; n=2; Actinomycetales|Rep: Putative
apramycin biosynthetic oxidoreductase 1 - Streptomyces
sp. DSM 40477
Length = 312
Score = 92.3 bits (219), Expect = 2e-17
Identities = 86/262 (32%), Positives = 113/262 (43%), Gaps = 24/262 (9%)
Query: 89 DCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM---RKHG--VYKLVYSSSCTVYG 143
+ V H A L V S YY+ N+ T + + + R+ G ++V+ SS VYG
Sbjct: 63 EAVCHLAGLTRVRGSGAAVGPYYRANVVATLNVLDALVARRRDGDDPPRVVFLSSGAVYG 122
Query: 144 EPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGR 203
+ P+ ESHPT TS YG +K E+ + + A +SLR FN G+ G
Sbjct: 123 PTGHAPVPESHPTAP--TSVYGATKLAAEQAVGWYAATGAVSA-VSLRLFNAAGSVRPG- 178
Query: 204 IGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIK 263
+G D S L+ VA GR L V G DGT VRD++HV D+A +A+
Sbjct: 179 VGPDDS----TLVARALAVASGRSPALPVNG------DGTTVRDFVHVADVADAVARAVA 228
Query: 264 LFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALA 323
P NLG SV E+VAA +G D AD A
Sbjct: 229 ---TPARRPARVFNLG-AVPASVREVVAAVEQVTGRRVPVEHGPPNPADQPWLAADTTAA 284
Query: 324 TRSLGWRATR-SLHDMCRDTWR 344
R LGW R SL M D WR
Sbjct: 285 RRDLGWTPERSSLERMIEDQWR 306
>UniRef50_A4F9Y4 Cluster: UDP-glucose 4-epimerase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: UDP-glucose
4-epimerase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 279
Score = 92.3 bits (219), Expect = 2e-17
Identities = 79/265 (29%), Positives = 115/265 (43%), Gaps = 33/265 (12%)
Query: 89 DCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRK-----HGVYKLVYSSSCTVYG 143
D V+H A L V ESVE P +Y+VN+ GT T+ E + V + V +S+ VYG
Sbjct: 34 DAVVHLAGLTRVRESVEHPGRFYRVNVGGTATVVEALMSTAAATGAVPRFVLASTGAVYG 93
Query: 144 EPEYLPINES---HPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHE 200
P+ PI E HP SPY +K E+++ D A ++R FN G+
Sbjct: 94 TPKKQPIGEDAMPHP-----QSPYAATKLAAEQLL-DAAAKTGGIAAATVRIFNAAGS-- 145
Query: 201 SGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQ 260
+G ++P A G + L+V+G DG+ VRDY+HV D+A V
Sbjct: 146 ---VGGHADADDTRIIPRALAAAAGHIPHLEVYG------DGSAVRDYVHVADIATAIVT 196
Query: 261 AIKLFHQPGFNGFHAI-NLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVAD 319
+ + G H + N+G T SV +++ A +G + AD
Sbjct: 197 VLTRSRE----GRHEVFNVG-ATPASVADIIDAAEAVTGRRVPVVRKPANPAESPELRAD 251
Query: 320 VALATRSLGWRATRS-LHDMCRDTW 343
R LGW RS L + D W
Sbjct: 252 TT-KLRGLGWEPRRSALRQLIADQW 275
>UniRef50_Q6MF46 Cluster: Probable UDP-glucuronat epimerase; n=2;
cellular organisms|Rep: Probable UDP-glucuronat
epimerase - Protochlamydia amoebophila (strain UWE25)
Length = 327
Score = 91.9 bits (218), Expect = 2e-17
Identities = 97/342 (28%), Positives = 147/342 (42%), Gaps = 37/342 (10%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M + + +TG AG++G H L +R GD I+ DN N Y K+ ALK
Sbjct: 10 MGKQIFITGIAGFIGFHLAQKLAKR---GD--RIIGYDNF-NPYYDTQLKRDRALK---- 59
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
L+ + + DI+ E L H +IH AA V S+++P Y + N++G
Sbjct: 60 LSKLGIEIIEGDIQNYEKLQNSILLHQTTHLIHLAAQAGVRYSLQEPATYLKTNVDGFLN 119
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
+ EI R H KL+Y+SS +VYG +P + T + S YG +K E+M
Sbjct: 120 ILEICRSHPHLKLIYASSSSVYGLNTKVPFSLEDRTDQQ-ASLYGVTKK-TNELMAKTYH 177
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQV-AVGRLKELKVFGDDYPT 239
+ I LR+F G P G P+ M Y S A+ + K +++F
Sbjct: 178 HLFGISSIGLRFFTVYG----------PWGRPD--MAYFSFANAIVQGKPIEIFN----- 220
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
+G RD+ +V D+ G + AI G NLG +L V G
Sbjct: 221 -EGKMQRDFTYVDDIVEGTIGAIDTEISLG-----VFNLGNHRPVELLYFVLLLEKELGI 274
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHD-MCR 340
GDV A AD+ +T+ LG++ S+ + +CR
Sbjct: 275 EAHKIWLPMQSGDVVATFADIQESTKQLGFQPKISIEEGLCR 316
>UniRef50_Q70PA0 Cluster: Putative uncharacterized protein; n=1;
Melittangium lichenicola|Rep: Putative uncharacterized
protein - Melittangium lichenicola
Length = 320
Score = 91.9 bits (218), Expect = 2e-17
Identities = 90/331 (27%), Positives = 140/331 (42%), Gaps = 29/331 (8%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTG AG++G H LL R GD ++ VDNL + + K L R+
Sbjct: 3 VLVTGAAGFIGYHVCERLLAR---GDT--VIGVDNLDTS--GDVTLKATRLSRLR--AAP 53
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F+++DIR A+A +F+ + V+H AA V + EY + N+ G + E+
Sbjct: 54 NFGFHRMDIRDAKACRELFDGARPERVVHLAARVGVRTLDSESPEYAETNVTGFLQVLEL 113
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
R+ V LV++SS +VYG +P +E + L S Y +K E+M
Sbjct: 114 CRRSRVEHLVFASSSSVYGAGSDMPFSEDSAADRPL-SLYAATKR-ANEMMAHAYSHQYA 171
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
I LR F+ G GR P P M ++ + GR EL +G
Sbjct: 172 MPITGLRLFSVYGPW--GR----PDMAP---MMFLRAMLEGRSLELH--------GEGKA 214
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RD+ ++ D+ V+ + G + +N+G GT S+ +V G
Sbjct: 215 QRDFTYIDDVVEALVRVLDA-APTGLPLYRVLNVGRGTPVSMSRLVDLLEEHLGTTAWVE 273
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSL 335
++ A ADV R G+R + +L
Sbjct: 274 MRSSRSEEMDATCADVTALERETGFRPSVTL 304
>UniRef50_A7HBK8 Cluster: NAD-dependent epimerase/dehydratase; n=4;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Anaeromyxobacter sp. Fw109-5
Length = 312
Score = 91.9 bits (218), Expect = 2e-17
Identities = 93/347 (26%), Positives = 152/347 (43%), Gaps = 45/347 (12%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M++ +L+TGGAG++GS LE D + V+D+LS+ + E P A +
Sbjct: 1 MAKRILITGGAGFIGSTIADLFLEAGWD-----VAVLDDLSSG---KRESVPPAAR---- 48
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
FY VD+R A AL+ + + + H AA V S+ +P VN+ G
Sbjct: 49 -------FYPVDVRSAAALE-VLKKERPQVICHQAAQIDVRRSMAEPRFDADVNVGGLLN 100
Query: 121 LFE--IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL 178
L + + K + L SS YG+ + +P E HP + S YG +K E+ ++
Sbjct: 101 LMQGAVEAKSVEHVLFASSGGATYGDTDRVPTPEDHP--QLPVSHYGAAKA-ASELYLNV 157
Query: 179 CVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYP 238
++ +LRY N G + DP G + + ++ GR +FGD
Sbjct: 158 YRANYGIPFTALRYSNVYGPRQ------DPHGEAGVVAIFCGRLLEGR--PCTIFGD--- 206
Query: 239 TADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
G+ RDY+ D+A ++ A + ++G +N+GTG V E+ A + A+G
Sbjct: 207 ---GSQTRDYVFAGDVARANLLAA----EKRYDG--PLNVGTGVETDVNELYAHLARAAG 257
Query: 299 XXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
G+ + D + A ++GWR L D R T+ W
Sbjct: 258 SDRPAEHAPARLGEQKRSCIDPSRAGAAVGWRPEVRLADGLRRTFEW 304
>UniRef50_A0A003 Cluster: MoeE5; n=1; Streptomyces ghanaensis|Rep:
MoeE5 - Streptomyces ghanaensis
Length = 340
Score = 91.1 bits (216), Expect = 4e-17
Identities = 98/349 (28%), Positives = 151/349 (43%), Gaps = 42/349 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTG AG++GSH V L R S + +V VD E P TG
Sbjct: 15 VLVTGAAGFIGSHLVTEL--RNSGRN---VVAVDRRPLPDDLESTSPP--------FTG- 60
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
++ + D+ +D + NI V H AAL V S + EY + N+ T L E
Sbjct: 61 SLREIRGDLNSLNLVDCL---KNISTVFHLAALPGVRPSWTQFPEYLRCNVLATQRLMEA 117
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV-SDK 183
+ GV ++V +SS +VYG + + + P SPYG +K E + D
Sbjct: 118 CVQAGVERVVVASSSSVYGGADGVMSEDDLPRP---LSPYGVTKLAAERLALAFAARGDA 174
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
+ ++ +LR+F G G+ P + L+ A R + ++++G DGT
Sbjct: 175 ELSVGALRFFTVYGP------GQRPDMFISRLIR-----ATLRGEPVEIYG------DGT 217
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
+RD+ HV D+ V+A+ L G +N+GTG+ SV E+V+ + +G
Sbjct: 218 QLRDFTHVSDV----VRALMLTASVRDRGSAVLNIGTGSAVSVNEVVSMTAELTGLRPCT 273
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNG 352
GDV + ADV A LG+ A L + W + +G
Sbjct: 274 AYGSARIGDVRSTTADVRQAQSVLGFTARTGLREGLATQIEWTRRSLSG 322
>UniRef50_A4CBV8 Cluster: NAD dependent epimerase/dehydratase family
protein; n=4; Proteobacteria|Rep: NAD dependent
epimerase/dehydratase family protein - Pseudoalteromonas
tunicata D2
Length = 332
Score = 90.6 bits (215), Expect = 5e-17
Identities = 91/350 (26%), Positives = 141/350 (40%), Gaps = 34/350 (9%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTG AG++G+ L +++ +DNL++ Y + K LKR+E T T
Sbjct: 4 LVTGAAGFIGNFVSERLCAMGH-----QVIGLDNLNDYY--DPALKLARLKRLEHFTNFT 56
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
F K+D+ EA+ +F + VIH AA V S+E P+ Y N+ G T+ E
Sbjct: 57 --FVKMDLADREAIANLFATEQFERVIHLAAQAGVRYSIENPMAYIDSNLVGMATILEGC 114
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
R + V LVY+SS +VYG +P E + S Y +K E+M
Sbjct: 115 RHNKVQHLVYASSSSVYGANTKIPFAEEDRVDYPV-SLYAATKK-SNELMAHTYSHLYSL 172
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT-- 243
LR+F G P G P ++ P++ A+ K +KVF + D T
Sbjct: 173 PTTGLRFFTVYG----------PWGRP-DMAPFLFTDAIANDKPIKVFNNGKMQRDFTYI 221
Query: 244 --------GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSN 295
++D I + A + QA+ F + N+G + + + N
Sbjct: 222 DDIVEGIIRIQDVIPAPNKQADNKQAVNKAEGSPF--YKLYNIGNNQPVELEQFITCIEN 279
Query: 296 ASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
A G GDV ADV+ +G++ L +W
Sbjct: 280 ALGKKAIKQYLPMQDGDVVRTFADVSGLESEIGFKPNTDLQSGINSFVQW 329
>UniRef50_Q1AWM7 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
NAD-dependent epimerase/dehydratase precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 331
Score = 90.2 bits (214), Expect = 7e-17
Identities = 106/352 (30%), Positives = 147/352 (41%), Gaps = 45/352 (12%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLS-------NAYCAEGEKKPEALKRI 58
LVTGG G++G+ V +L + +G + VVDNLS A C E PE +
Sbjct: 4 LVTGGCGFIGTALVRSLAQ---EGGGHAVRVVDNLSVGTREDLGAACGFREVSPEGAGPL 60
Query: 59 EELTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGT 118
E G+ V DI R+ + V+H AA V SVE P N+ GT
Sbjct: 61 E---GEGVELVVGDILDEGLARRVCAGAEV--VVHLAASTGVAPSVEDPRRDCVTNVLGT 115
Query: 119 CTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL 178
E R G + V++SS GE E PI+E SPYG K E
Sbjct: 116 LNYLEAARAAGARRFVFASSGAAAGEVE-PPIHEG--VCPRPVSPYGAGKLAGE------ 166
Query: 179 CVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDDY 237
W L A G + SG N+++ +I + A G + L+++G
Sbjct: 167 AYCSAYWRTYGLE----TVALRFGNVYGPGSGHKNSVVARFIRRAARGEV--LEIYG--- 217
Query: 238 PTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYS---VLEMVAAFS 294
DGT RD+I++ DL V+A++L G G + TG+ S V+E++
Sbjct: 218 ---DGTQTRDFIYIDDL----VRALRLAATAGGVGGEVFQIATGSETSVGEVVELLLPVL 270
Query: 295 NASGXXXXXXXXXX-XXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
A+G GDV N AD + A R LGWRA L + R T W
Sbjct: 271 AAAGIKGVRVERASPRPGDVARNYADTSKARRLLGWRAEVGLEEGLRRTVGW 322
>UniRef50_A5GIA6 Cluster: NAD dependent epimerase/dehydratase; n=19;
Bacteria|Rep: NAD dependent epimerase/dehydratase -
Synechococcus sp. (strain WH7803)
Length = 343
Score = 90.2 bits (214), Expect = 7e-17
Identities = 91/352 (25%), Positives = 141/352 (40%), Gaps = 28/352 (7%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL 61
+R +L+TG AG++G+ LL+R GD +V +D+L++ Y + K L++IE +
Sbjct: 5 ARPILITGAAGFIGAALAQRLLQR---GD--RVVGIDSLNSYY--DPSLKQARLQQIEAV 57
Query: 62 TGKTV-HFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
F + A+AL +F V++ AA V S+E P Y Q N+ G
Sbjct: 58 AAPGAWSFCHQALEAADALQELFAREKPRVVVNLAAQAGVRYSLENPAAYIQSNLVGFGN 117
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
+ E R HGV LVY+SS +VYG LP +E P + S Y SK E+M
Sbjct: 118 ILEGCRHHGVENLVYASSSSVYGGNRNLPFHEQQPVNHPV-SLYAASKK-ANELMAHTYS 175
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
LR+F G P G P ++ P + A+ + +KVF
Sbjct: 176 HLYGLPATGLRFFTVYG----------PWGRP-DMAPMLFAKAILAGEPIKVFNHGKMQR 224
Query: 241 DGTGVRDYI----HVCD---LAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAF 293
D T + D + CD A + A+ N+G +L +
Sbjct: 225 DFTYIDDIVEGVLRCCDKPATANPNFDALAPDPSTAAAPHRVFNIGNSQPTELLRFIEVM 284
Query: 294 SNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
A G GDV A AD + +G++ + + + W
Sbjct: 285 EQALGRQAIKDFQPMQPGDVVATAADTSALESWVGFKPSTPIEEGIAQFAHW 336
>UniRef50_Q8KWC8 Cluster: RB114; n=5; Proteobacteria|Rep: RB114 -
Ruegeria sp. PR1b
Length = 382
Score = 89.8 bits (213), Expect = 9e-17
Identities = 101/349 (28%), Positives = 158/349 (45%), Gaps = 52/349 (14%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LV GG G++GSH V+ +L + G + V+D ++PEA + + G
Sbjct: 72 LVIGGCGFIGSH-VVDVLHQAGMG----LRVLD-----------RRPEAFRA--PVPGVE 113
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+ + R A+ + + +D V+H A+ S P+ N+ T +L E+M
Sbjct: 114 YVYCDMQDR-AQLFEAV---SGVDAVVHLASTTVPATSNLDPVADVSGNLVTTLSLLEVM 169
Query: 126 RKHGVYKLVY-SSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEE-IMKDLCVSDK 183
R GV ++VY SS TVYG P+ ++E HP S YG K E+ + + +
Sbjct: 170 RAAGVRRMVYLSSGGTVYGVPQQDLVSEDHPLNP--ISSYGIVKVAVEKYLFMEHQLHGL 227
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
++ + LR NP G + R GI + ++ +++ R +E++V+G DG+
Sbjct: 228 EYVV--LRASNPYGPRQGHR------GIQGLIGTHLWRLS--RQEEIEVWG------DGS 271
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMV----AAFSNASGX 299
VRD++HV DLA Q L G +G N G G G SV E+V A + + G
Sbjct: 272 IVRDFLHVRDLA----QLCLLAMTSGKSGI--FNAGRGQGASVAEVVEQICATVAASGGR 325
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEA 348
DV V D A LGW+A +L D +TW W +A
Sbjct: 326 SVAPIYKPGRNFDVPRVVLDTTRARAELGWQAEITLQDGIAETWDWVQA 374
>UniRef50_A1BC39 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Paracoccus denitrificans PD1222|Rep: NAD-dependent
epimerase/dehydratase - Paracoccus denitrificans (strain
Pd 1222)
Length = 316
Score = 89.8 bits (213), Expect = 9e-17
Identities = 100/349 (28%), Positives = 156/349 (44%), Gaps = 48/349 (13%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEAL-KRIE 59
M+ LVTGGAG++GSH V L + G+ +VV+DNLS+ KPE L ++E
Sbjct: 1 MTHRTLVTGGAGFIGSHLVEHL---AAAGE--RVVVLDNLSSG-------KPENLPPQVE 48
Query: 60 ELTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTC 119
+ G DI + + + +DCV H AAL +V E ++ +++N++ T
Sbjct: 49 LIAG--------DITDGALVGELVQ--GVDCVFHLAALVSVQECIKDWELGHRINLDATV 98
Query: 120 TLFE--IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKD 177
LF + G +VY+SS VYG+ E+ + + SPYG K CE +
Sbjct: 99 GLFHAAARARPGGVPVVYASSAAVYGDRSGSTCCET--SLPAPISPYGVDKLGCEHQARA 156
Query: 178 LCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKEL--KVFGD 235
+ K + LR+FN G +DP+ + IS+ RL + VFG
Sbjct: 157 M-AEIHKLRSVGLRFFNVYGPR------QDPA---SPYAGVISKFCANRLADSPHTVFG- 205
Query: 236 DYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSN 295
DG RD+I+V D+ G V+A + + Q G G NL TG +++ + +
Sbjct: 206 -----DGLQSRDFIYVADIVEGLVRA-RAYAQ-GQEGAAVFNLCTGAETTLVGLASEIDG 258
Query: 296 -ASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTW 343
A GD+ ++ D +LA R LG+ A + W
Sbjct: 259 IADRGPTPIIHADPRSGDIRMSLGDPSLAARDLGFTARTDIRSGLSRLW 307
>UniRef50_Q01U23 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Solibacter usitatus Ellin6076|Rep: NAD-dependent
epimerase/dehydratase - Solibacter usitatus (strain
Ellin6076)
Length = 317
Score = 89.4 bits (212), Expect = 1e-16
Identities = 92/341 (26%), Positives = 147/341 (43%), Gaps = 39/341 (11%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
+VTGGAG++GS LL + +VV+DNL + G + +EE+ +
Sbjct: 5 VVTGGAGFIGSAITRRLLAEGAG----RVVVIDNLLS-----GRES-----NLEEIRAR- 49
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+ F + DIR E + + + V H AA+ +V S+E P+ + VN NGT +
Sbjct: 50 IDFQRADIRNYEEIAPLIRGAAV--VFHEAAIPSVPRSIEDPVPSHDVNANGTFNVLRAA 107
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLP-INESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
++ ++VY++S + YG+ E LP + + P K SPY K E ++
Sbjct: 108 KEGQAGRVVYAASSSAYGDTEVLPKVEDMTPRPK---SPYALQK-LLGEYYCNVFTGVYG 163
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
++LRYFN G +DP + ++ + A+ R +FG DG
Sbjct: 164 LETVALRYFNVYGPR------QDPGSPYSGVLSLFMKAALNRTAP-TIFG------DGEQ 210
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RD+ +V D+A +++A + G G N G G ++ + A G
Sbjct: 211 SRDFTYVEDVAELNLKAAR---AKGVAG-KVYNGGNGGRITLNQAWALLQKLEGIEIPSV 266
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV + AD LA R LG S + R T W
Sbjct: 267 YGPPRAGDVRDSQADTTLAVRELGHAPRYSFEEGMRLTLEW 307
>UniRef50_Q93KX6 Cluster: Putative UDP-glucose 4-epimerase; n=1;
Streptomyces viridochromogenes|Rep: Putative UDP-glucose
4-epimerase - Streptomyces viridochromogenes
Length = 322
Score = 89.0 bits (211), Expect = 2e-16
Identities = 100/341 (29%), Positives = 141/341 (41%), Gaps = 42/341 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++GSH V LE + E+ V+D+L+ G+ E L +
Sbjct: 13 LLVTGGAGFIGSHVVDAFLEAGA-----EVTVLDDLTT-----GDP--------ERLDPR 54
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V +VD+ A ALD + D + H AA V SV P +VN+ GT + E
Sbjct: 55 AV-IRRVDVTDAAALDEAVRSARPDVICHLAAQIDVRVSVATPAVDARVNVEGTINVLEA 113
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
G + S+ +YGE +P NE T +PYG +KY C E L
Sbjct: 114 AHAVGARVVFASTGGALYGEGVPVPTNED--TLPRPGAPYGTAKY-CAEKYIGLFNRLHG 170
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
LR N G +S P G + Y + G + VFG DG+
Sbjct: 171 TEHSVLRLGNVYGPRQS------PGGEAGVIAIYCGLASEGGVP--TVFG------DGSQ 216
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RDY++V D+AA V G G + TG G +VLE++ + ASG
Sbjct: 217 TRDYVYVGDVAAAFVAPY------GTVGPASGTSDTGKGSTVLEVLDHIAAASGRDLPPR 270
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
G++ + DV LGW A+ L T+ W
Sbjct: 271 FAPRRPGEIQHSTLDVTRVAADLGWTASVPLEKGIAATYAW 311
>UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=9;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Anaeromyxobacter sp. Fw109-5
Length = 373
Score = 88.2 bits (209), Expect = 3e-16
Identities = 89/342 (26%), Positives = 143/342 (41%), Gaps = 29/342 (8%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+++TG AG++GSH LL DG E+ +DNL++ Y ++ AL E +
Sbjct: 45 IVLTGCAGFIGSHVARRLLR---DGH--EVSGLDNLNDYYDPSLKRARLALLAPE----R 95
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F D+ EALD + + + V+H AA V SV P Y + N++G + +
Sbjct: 96 GFRFTAADVADREALDAVLDEAEPEYVVHLAAQVGVRNSVRNPRAYAETNLDGFFNVLDG 155
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+ GV LVY+SS +VYG E +P +E P + S Y +K EIM +
Sbjct: 156 CARRGVRHLVYASSSSVYGSNEKVPFSEEDPVDHPI-SFYAATKK-ANEIMAHAYSHLNR 213
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
LR+F G P G P ++ P + A+ R + + +F G
Sbjct: 214 LPTTGLRFFTVYG----------PWGRP-DMAPILFGRAILRGEPITLFN------HGRM 256
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQP-GFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
+RD+ +V D+ + +P + +N+G ++ E VA G
Sbjct: 257 LRDFTYVDDVVEVVTALVPRPPEPEDAAPYRVLNVGNDRPVALEEFVAILERHLGRPALR 316
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV A ADV ++G+ + + R W
Sbjct: 317 KYAPMQPGDVPATWADVRRLQATVGFVPRTPIEEGLRRMTEW 358
>UniRef50_Q93N66 Cluster: Dehydratase-like protein; n=14; cellular
organisms|Rep: Dehydratase-like protein - Coxiella
burnetii
Length = 344
Score = 87.8 bits (208), Expect = 4e-16
Identities = 95/332 (28%), Positives = 141/332 (42%), Gaps = 44/332 (13%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
+VTGGAG++GSH V LL+ ++ V+DNL + + E +LT
Sbjct: 7 IVTGGAGFIGSHMVDLLLDCG-----FQVRVIDNLKGGH----RRNLEHRANNPDLT--- 54
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
F DI A +FEN +D V HFA + + S+E P++Y Q N+ GT + E
Sbjct: 55 --FEIKDICELSAPHPLFEN--VDYVFHFAGIGDIVPSIENPIDYLQTNVMGTVRVLECA 110
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
R V KLVY++S + YG + +P E HP PY SKY EE
Sbjct: 111 RAANVKKLVYAASSSCYGLAD-VPTREDHPIAPQY--PYALSKYLGEEAAFH-WFQVYGL 166
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
+ S+R FN G R+ +G+ + + + K V G DGT
Sbjct: 167 PVNSIRIFNAYGT----RV--RTTGVYGAVFGVFFKQKLAD-KPFTVVG------DGTQR 213
Query: 246 RDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXX 305
RD+++V D+A ++A + + G NLG G S+ +V
Sbjct: 214 RDFLYVTDVARAFLKAAET-RKVG----ETWNLGAGNPQSINRLVELIGG------EVEY 262
Query: 306 XXXXXGDVTANVADVALATRSLGWRATRSLHD 337
G+ AD++ R LGW T + D
Sbjct: 263 IPKRPGEPDCTWADISKIKRDLGWEPTITFAD 294
>UniRef50_Q1WTH1 Cluster: UDP-glucose 4-epimerase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
UDP-glucose 4-epimerase - Lactobacillus salivarius
subsp. salivarius (strain UCC118)
Length = 319
Score = 87.4 bits (207), Expect = 5e-16
Identities = 82/324 (25%), Positives = 151/324 (46%), Gaps = 41/324 (12%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M + LVTGGAG++GS+ + ++ S GD E+VVV A C E + LK
Sbjct: 1 MRKKYLVTGGAGFIGSNLIEKII---SQGD--EVVVVGRHLPAECKEDDNN---LK---- 48
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+ FY+ D+ E ++++ D ++ AA+ ++ ++ +PL + +N
Sbjct: 49 ---DNITFYQADVTYYEFMEQLLIKEKFDYIVLLAAVISISGTIAEPLSTHFINQEAILY 105
Query: 121 LFEIMRKH--GVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL 178
++EI+RK+ V K++++SS VYG P E P SL +PY K+ E +
Sbjct: 106 IYEIIRKNKLKVKKVLFTSSSAVYGNIADTPRREDMPV--SLENPYAIDKFASE---RYA 160
Query: 179 CVSDKKWAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDD 236
+K + I +++R+FN G + + G+ +G+ ++ + KE ++ G
Sbjct: 161 MFYEKVYGIPTVAVRFFNVYGPRQKAQ-GKS-AGVCAIILDCLLND-----KEFRLNG-- 211
Query: 237 YPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNA 296
DG RDY++V D + +K P +G N+ +G S+++++ AF
Sbjct: 212 ----DGKQTRDYMYVTDAVDATLMLLK---DPQISG-KIFNVASGKSVSLIDLIVAFEEI 263
Query: 297 SGXXXXXXXXXXXXGDVTANVADV 320
+G D ++AD+
Sbjct: 264 TGKKLKIIHNKGLKFDTKNSLADI 287
>UniRef50_Q2NIA3 Cluster: Putative UDP-glucose 4-epimerase; n=1;
Methanosphaera stadtmanae DSM 3091|Rep: Putative
UDP-glucose 4-epimerase - Methanosphaera stadtmanae
(strain DSM 3091)
Length = 315
Score = 87.4 bits (207), Expect = 5e-16
Identities = 91/337 (27%), Positives = 152/337 (45%), Gaps = 39/337 (11%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
+VTGGAG++GSH TLLE ++ ++DN++ E K + RIE + G
Sbjct: 7 VVTGGAGFIGSHITETLLENNVS----KVTIIDNMTTGNI-ENLKNLDH-DRIELVCG-- 58
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
DIR + + I ENH D + H AAL +V ES+E+P + NI+G+ + +
Sbjct: 59 ------DIRTLD-MKPILENH--DYLFHEAALISVFESIEQPKATNKTNIDGSFNVLQAA 109
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
+ + K++ +SS VYGE E LP E+ P SPY SK E+
Sbjct: 110 YESNIKKVISASSAAVYGETEVLPNVETLPL--QPLSPYAVSKALL-ELYSYTFTQTYHL 166
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
LRYFN G + + SG+ + +IS A+ + ++G DG
Sbjct: 167 PTACLRYFNVFGPRQ--KADSPYSGV---IPKFIS--ALLNNETPVIYG------DGEQT 213
Query: 246 RDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXX 305
RD+I+V ++A + + + + G N+ G ++ E++ G
Sbjct: 214 RDFIYVKNIAKANYE-VAINDVTG-----VFNIAHGKTTTINELLEIICEIMGYDCNPKY 267
Query: 306 XXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDT 342
GD+ +VAD++ A + G+++ ++T
Sbjct: 268 LPQKDGDIRDSVADISKAEETFGFKSEHDFKKELKET 304
>UniRef50_Q84CM4 Cluster: Nucleotide sugar epimerase; n=4;
Proteobacteria|Rep: Nucleotide sugar epimerase -
Zymomonas mobilis
Length = 337
Score = 87.0 bits (206), Expect = 7e-16
Identities = 88/335 (26%), Positives = 146/335 (43%), Gaps = 36/335 (10%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
A+L+TG AG++GS +LLER G+ EIV +DNL++ Y E +KK L +++L
Sbjct: 2 AILITGIAGFIGSFAAKSLLER---GE--EIVGIDNLNDYYDPELKKK--RLAELKKLKN 54
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
+HF +D L+ E + D +IH A V S+ P Y N+ G + E
Sbjct: 55 GKLHFSPIDFSDGALLNNTLEKFDFDRIIHLGAQAGVRYSLINPQIYGDSNLIGHLNILE 114
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPIN-ESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
+ R V +VY+SS +VYG LP +S P + S Y +K E++ +
Sbjct: 115 LARHRKVRHMVYASSSSVYGNRSTLPFKVDSQPDYPA--SLYAATKR-AGEMLSESYAYL 171
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ + LR+F G G P+ M +I + + + + +F +G
Sbjct: 172 YRIPLTGLRFFTVYGIW----------GPPDMAM-WIFTKKILQKQPIMLFN------NG 214
Query: 243 TGVRDYIHVCDLAAGHVQAI--------KLFHQPGFNGFHAINLGTGTGYSVLEMVAAFS 294
RD+ ++ D +G + A+ K+ N + N+G ++ +V
Sbjct: 215 EMQRDFTYIDDAVSGLIAALDNPPQDNNKIKSGGSLNPHNLYNIGNHHPENLKYLVELLE 274
Query: 295 NASGXXXXXXXXXXXXGDVTANVADVALATRSLGW 329
A G GDV+ AD+ + R LG+
Sbjct: 275 EACGCHAIKELRPMQAGDVSTTYADIETSKRDLGF 309
>UniRef50_O95455 Cluster: dTDP-D-glucose 4,6-dehydratase; n=24;
Eumetazoa|Rep: dTDP-D-glucose 4,6-dehydratase - Homo
sapiens (Human)
Length = 350
Score = 86.6 bits (205), Expect = 9e-16
Identities = 65/200 (32%), Positives = 99/200 (49%), Gaps = 16/200 (8%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL 61
++ VLVTGGAG++ SH +++L+E D I+ +D L YCA +LK +E +
Sbjct: 17 AKRVLVTGGAGFIASHMIVSLVE---DYPNYMIINLDKLD--YCA-------SLKNLETI 64
Query: 62 TGKTVH-FYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+ K + F + DI + + +FE ID V+HFAA V S + E+ VN+ GT
Sbjct: 65 SNKQNYKFIQGDICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHV 124
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L + V K +Y S+ VYG +ES P K T+PY SK E ++
Sbjct: 125 LVSAAHEARVEKFIYVSTDEVYGGSLDKEFDESSP--KQPTNPYASSKAAAECFVQSYW- 181
Query: 181 SDKKWAIISLRYFNPVGAHE 200
K+ ++ R N G H+
Sbjct: 182 EQYKFPVVITRSSNVYGPHQ 201
>UniRef50_A4MIF2 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Geobacter bemidjiensis Bem|Rep: NAD-dependent
epimerase/dehydratase - Geobacter bemidjiensis Bem
Length = 288
Score = 86.2 bits (204), Expect = 1e-15
Identities = 84/259 (32%), Positives = 116/259 (44%), Gaps = 29/259 (11%)
Query: 83 FENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVY 142
F+ I VIH V S E P +Y+ N GT L + R G +LVY S+ VY
Sbjct: 54 FQGRGITHVIHLGGRTFVPHSWEDPGAFYRANTLGTQQLLDFCRISGA-RLVYVSA-YVY 111
Query: 143 GEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESG 202
G P LPI ESHP + +PY SK+ EE+ + + + LR FN G +
Sbjct: 112 GVPHTLPIAESHPVAPN--TPYNHSKWLAEELCR-FYADHFEVPVTVLRPFNIFGPGQ-- 166
Query: 203 RIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAI 262
GED L+P I LK+ K G D RDY+HV DLA + A+
Sbjct: 167 --GED------FLIPTI-------LKQAK-SGGTITVKDAAPRRDYLHVDDLAEALLLAL 210
Query: 263 KLFHQPGFNGFHAINLGTGTGYSVLEMV-AAFSNASGXXXXXXXXXXXXGDVTANVADVA 321
L +P F+ F N+G+G SV E++ A + +V VAD++
Sbjct: 211 DL--EPRFSLF---NVGSGRSISVGELLDMAVRYSPRPLCWQATGEIRVNEVPDTVADIS 265
Query: 322 LATRSLGWRATRSLHDMCR 340
TR+LGW R+L +
Sbjct: 266 AITRALGWLPRRTLEQFLK 284
>UniRef50_A4FLF3 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: NAD-dependent
epimerase/dehydratase - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 324
Score = 86.2 bits (204), Expect = 1e-15
Identities = 96/339 (28%), Positives = 151/339 (44%), Gaps = 46/339 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
V+VTGG+G+VG V +ER G P+ ++ +++P E+L G
Sbjct: 19 VVVTGGSGFVGRAVVRAFVER---GTPVTVI-------------DQQPLP----EDLRGD 58
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V D+ A + ++H AA+ +V SV++P E Y N+ T L E+
Sbjct: 59 LVTHVAGDLGDPAAREAAV-TEGAAGIVHLAAITSVLRSVDRPAETYAANVAVTQELLEL 117
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
R G+ + V +S+ V G+ I+ES P + LT PYG +K CE ++
Sbjct: 118 ARLRGLGQFVLASTNAVVGDIGRGTISESLPL-RPLT-PYGATKAACEMLLSGY-AGAYG 174
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
A +LR+ N G +G S IP + ++ V +V+G DG+
Sbjct: 175 LATCALRFTNIYGP----GMGHKDSFIPRLMRAALAGAGV------EVYG------DGSQ 218
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RD++HV D+ G + A ++G AI +G G SV E++ A A+G
Sbjct: 219 SRDFVHVDDVVRGVLAA----WDKQYSG-TAI-IGAGRSISVTELIEAVRTATGRPLPVT 272
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTW 343
G++ A + DVA A R LG+ + L D R W
Sbjct: 273 HVPAKNGEMPAVIVDVAKAGRELGYTPSVELTDGLRTVW 311
>UniRef50_A1FN39 Cluster: NAD-dependent epimerase/dehydratase; n=23;
cellular organisms|Rep: NAD-dependent
epimerase/dehydratase - Pseudomonas putida W619
Length = 355
Score = 86.2 bits (204), Expect = 1e-15
Identities = 90/316 (28%), Positives = 140/316 (44%), Gaps = 39/316 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+L+TGGAG++GSH LL + + V+D+LS K + L +L
Sbjct: 51 ILITGGAGFIGSHLCDALLAKG-----YAVRVLDDLSTG-------KRDNL----QLGNP 94
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ + D+ A + R V+H AA+ +V SVE P++ +Q N GT + E
Sbjct: 95 RLELVEGDVADAALVQRAAAG--CSAVVHLAAVASVQASVEDPVKTHQSNFIGTLNVCEA 152
Query: 125 MRKHGVYKLVYSSSCTVYG-EPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
MR GV ++V++SS VYG E I E P K+ +PY K E+ + D
Sbjct: 153 MRLQGVRRVVFASSAAVYGNNGEGQSIAEDTP--KAPLTPYAVDKLASEQYL-DFYRRQH 209
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
+ R+FN G +DPS + ++ S+ A L + VFG DG
Sbjct: 210 GLEPVVFRFFNIFGPR------QDPSSPYSGVISIFSERATQGL-PITVFG------DGE 256
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RD+++V DL VQA++ QP A+N+G S+ +++ A G
Sbjct: 257 QTRDFLYVGDLVQVMVQALE---QPQVEE-GAVNIGLNQATSLNQLLKALETVVGSLPPV 312
Query: 304 XXXXXXXGDVTANVAD 319
GD+ + AD
Sbjct: 313 SYGEARSGDIRHSRAD 328
>UniRef50_A0UVI4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Clostridium cellulolyticum H10|Rep: NAD-dependent
epimerase/dehydratase - Clostridium cellulolyticum H10
Length = 309
Score = 86.2 bits (204), Expect = 1e-15
Identities = 94/346 (27%), Positives = 149/346 (43%), Gaps = 48/346 (13%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
L+TGGAG+VG H LL+ E+++ DNLS+ L+ I TG
Sbjct: 4 LITGGAGFVGCHIAKQLLDENKG----EVIIYDNLSSG----------KLQNIP--TG-- 45
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
F + DIR ++ ++ + E +D V H AA ++ S E +N GT + E M
Sbjct: 46 CRFIEGDIRDSKKIEEVLE--GVDVVFHNAAFVSIRNSYTMLKEEMDINCYGTQNILEGM 103
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
K V K+V++SS YG P +PI E + SPYG SK CE K + K++
Sbjct: 104 VKQRVRKIVFASSMAAYGWPRQIPITED--CDLAPISPYGFSKARCELYCK---IFAKRF 158
Query: 186 AI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
I + LRY N GI L PY+ V + + DG
Sbjct: 159 GISYVILRYCNIY-------------GIKQTLSPYVG-VLTTFINQALSSQPITVNGDGE 204
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
++D+++V D+A ++ A++ + N+G+G SV +A ++
Sbjct: 205 QIKDFVNVEDIAHANLLAME------YEKNDIFNIGSGIKTSV-NQLADMVLSNFKDGKK 257
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
G+V + AD++ A LG++A L + W + N
Sbjct: 258 IYMPLPEGEVDSICADISKAQNLLGYKAEGDLEKLLPQIIEWWKNN 303
>UniRef50_Q12UG3 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Euryarchaeota|Rep: NAD-dependent epimerase/dehydratase -
Methanococcoides burtonii (strain DSM 6242)
Length = 299
Score = 86.2 bits (204), Expect = 1e-15
Identities = 93/325 (28%), Positives = 137/325 (42%), Gaps = 48/325 (14%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+ +L+TGGAG VGS+ V E E+ ++DN S+ + PE + I
Sbjct: 2 KRILITGGAGQVGSYLVDRFHEEN------EVTILDNYSSP---TRKDVPEGVSVI---- 48
Query: 63 GKTVHFYKVDIRCAEALDRIFEN-HNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
K DIR D I E+ N D +IH AA +V S+ +P Q NI GT L
Sbjct: 49 -------KADIR-----DDISEHMSNTDVIIHTAAQISVVRSMNEPFFDAQNNIMGTLNL 96
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
E R + + VY SS YG P +PI E+HP + SPYG SK E+ C+
Sbjct: 97 LEEARHANIERFVYFSSAATYGNPLKVPIGETHP--QEPLSPYGASKLAGEK----YCIM 150
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDP-SGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
K + P + + +P SG+ + +I +V+ G +FGD T
Sbjct: 151 YNKAYGLPTTCIRPFNIYSPRQDPSNPYSGV---ISKFIDKVSGG--ASPTIFGDGEQTR 205
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
D VRD + + DL AI + N TG ++ E+ + G
Sbjct: 206 DFIYVRDIVDLVDLMISKRTAIG----------ESFNAATGRSTTINELAEIIIDLFGKE 255
Query: 301 XXXXXXXXXXGDVTANVADVALATR 325
GD+ +VAD++ A +
Sbjct: 256 LKADYKDPLEGDIKHSVADISKAEK 280
>UniRef50_Q1AWT4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: NAD-dependent
epimerase/dehydratase - Rubrobacter xylanophilus (strain
DSM 9941 / NBRC 16129)
Length = 317
Score = 85.8 bits (203), Expect = 2e-15
Identities = 101/328 (30%), Positives = 140/328 (42%), Gaps = 41/328 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTG AG++GSH V LL + E+V VD + Y E+K L E +G+
Sbjct: 4 ILVTGAAGFIGSHLVDRLL-----AEGCEVVGVDAFTRYY--PRERKLRNLSSAAE-SGR 55
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT--LF 122
F V+ E LD ++ V H A V S E Y + N CT L
Sbjct: 56 ---FRLVEGDLLE-LDLGLLLRGVEAVAHLAGEPGVRSSWGAGFEVY-LRRNVLCTERLL 110
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
E + + G + V +SS +VYG P+ E HP + SPYG SK EE+++ L +
Sbjct: 111 EAVWRAGTPRFVLASSSSVYGPDGGRPVAEDHPLRPA--SPYGLSKLSAEELVR-LYARE 167
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ LRYF G + + L +I+ GR ++VFGD G
Sbjct: 168 RGVRGTVLRYFTVYGPRQRPEMA---------LSRFIAAAHAGR--PVEVFGD------G 210
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
VRD +V D V A+ + G G A N+G G SV M+ A +G
Sbjct: 211 GQVRDMTYVSDAVEATVAAL----ERGAGG--AYNVGGGVRVSVRGMLEAVREVTGRPVE 264
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWR 330
GDV + AD A R LG+R
Sbjct: 265 AVYGEAAAGDVRSTWADSRRAERELGYR 292
>UniRef50_A1VG42 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep:
NAD-dependent epimerase/dehydratase - Desulfovibrio
vulgaris subsp. vulgaris (strain DP4)
Length = 316
Score = 85.4 bits (202), Expect = 2e-15
Identities = 94/342 (27%), Positives = 151/342 (44%), Gaps = 45/342 (13%)
Query: 7 VTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKTV 66
V G +G++GSH V LLE +A+ + P L E ++ TV
Sbjct: 8 VLGASGFLGSHLVHHLLEAGCH------------VHAFSRVPRRNP--LVTDELMSSCTV 53
Query: 67 HFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMR 126
+ D A+ ++R E D H + S + P + N++G L E +R
Sbjct: 54 --FTGDFFNAQDVERALEG--CDVCFHLVSTTIPKTSNDDPSRDVRENLSGALDLLECVR 109
Query: 127 KHGVYKLVYSSSC-TVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
+ GV K+VY+SS +YG+ I+ESHPT + YG K E K L + + +
Sbjct: 110 RTGVRKVVYTSSGGAIYGKHLMPRISESHPTDPLCS--YGIVKLAVE---KYLALYHELY 164
Query: 186 AI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
I +LR NP G + + G+ ++ ++ R + L V+GD G+
Sbjct: 165 GIDYAALRISNPFGPLQRAGAEQGVIGV------FLGRIL--RNEPLHVWGD------GS 210
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
VRDYI+V D+A V A ++ + H N+G+G G S+ E++ + +G
Sbjct: 211 VVRDYIYVEDVARALVLAARMKTE-----HHVFNIGSGAGLSLNEIIGMMRSVTGRDVVV 265
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
DV +V DV+ A L W+A+ + + R TW W
Sbjct: 266 KYDQNRAFDVPYSVLDVSRALDELDWKASIAFDEGLRRTWEW 307
>UniRef50_Q9HSU9 Cluster: GDP-D-mannose dehydratase; n=2;
Halobacterium salinarum|Rep: GDP-D-mannose dehydratase -
Halobacterium salinarium (Halobacterium halobium)
Length = 309
Score = 85.4 bits (202), Expect = 2e-15
Identities = 92/326 (28%), Positives = 151/326 (46%), Gaps = 41/326 (12%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTG AG++GSH LL+R D + VDN + + ++ E L+ + +
Sbjct: 5 LVTGVAGFIGSHLAAALLDRGYD-----VRGVDNFATGH----DQNLEPLRGTGDFS--- 52
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
FY+ DIR A+ + + + +D V H AA +V SVE P+ VN GT T+ +
Sbjct: 53 --FYEADIRDADLVADV--TNGVDYVFHQAADSSVPRSVEDPVTTTDVNCTGTATVIDAA 108
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEI-MKDLCVSDKK 184
R+ V +V +SS +YG E P ES + SPY SK++ E++ ++ + D
Sbjct: 109 READVDTVVVASSAAIYGSTETFPKVES--MTEQPESPYALSKHYTEKLALQASELYDID 166
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDDYPTADGT 243
A +LRYFN G +DP+G ++P +IS + G + ++G DG
Sbjct: 167 TA--ALRYFNIYGPR------QDPNGDYAAVIPKFISLMLDG--ERPVIYG------DGE 210
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RD+ + + +++A + G A N+G G +V E+V ++
Sbjct: 211 QSRDFTFIDNAIQANIRAAE-----GDVTGEAFNVGCGGRVTVNELVDVLNDLLDTDIDP 265
Query: 304 XXXXXXXGDVTANVADVALATRSLGW 329
GDV + AD++ A L +
Sbjct: 266 IYDDPRPGDVRHSHADISKARELLSY 291
>UniRef50_A5UK04 Cluster: UDP-glucose 4-epimerase; n=2;
Euryarchaeota|Rep: UDP-glucose 4-epimerase -
Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM
861)
Length = 309
Score = 85.4 bits (202), Expect = 2e-15
Identities = 90/351 (25%), Positives = 158/351 (45%), Gaps = 47/351 (13%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL 61
++ +++TGG G++GSH L+E + + ++DNLS+ E K P E L
Sbjct: 3 NKNIIITGGLGFIGSHIADELIEDNN------VTIIDNLSSGK-VENLKNPAH----ENL 51
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
T K ++ LD F + D + H AA+ +V SV P++ N+N T L
Sbjct: 52 T-----IIKNNLNDMN-LDETFAD--TDYIFHLAAMASVPLSVNDPIKCNDNNVNSTIKL 103
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
+ V K+++SSS VYG +P+ ES TSPY SK CE ++
Sbjct: 104 LTAAKNQNVKKVIFSSSSAVYGNNANMPLKESEL--MMPTSPYAASKANCELYLQ---AF 158
Query: 182 DKKWAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
++ + + I+LRYFN G + + + + IPN +I A+ + ++G
Sbjct: 159 EESYGLKSIALRYFNVFGPKQD-KNSQYAAVIPN----FID--AILNNEHPIIYG----- 206
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
DG RD+I V D+A ++ A + + G +N+ TG +V + +++
Sbjct: 207 -DGQQTRDFIFVKDVAKANIAAA----ESNYTG--PVNIATGEKLTVNRLYEIIADSMES 259
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRS-LHDMCRDTWRWQEAN 349
GD+ ++AD+ + + ++A S +T +W + N
Sbjct: 260 DLEPVYVDKRKGDIEHSIADIDKMS-EINFKADSSNFEKQINETIQWFKEN 309
>UniRef50_Q2RKH0 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Firmicutes|Rep: NAD-dependent epimerase/dehydratase -
Moorella thermoacetica (strain ATCC 39073)
Length = 323
Score = 85.0 bits (201), Expect = 3e-15
Identities = 96/347 (27%), Positives = 146/347 (42%), Gaps = 47/347 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAY--CAEGEKKPEALKRIEELT 62
+LVTG G++GSH L+ +G + V N N + E E K + IE T
Sbjct: 3 ILVTGAGGFIGSHLTEKLVR---EGHKVRAFVHYNSRNTWGWLEESEVKDD----IEVFT 55
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
G DIR +++ I+ V H AAL + S P+ Y + N+ GT +
Sbjct: 56 G--------DIRDYDSVRASLRG--IEVVFHLAALIGIPYSYVTPVAYIKTNVEGTYNIC 105
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
+ R+ G+ ++V++S+ VYG Y+PI+E+HP SPY SK +++ S
Sbjct: 106 QAAREEGLRRVVHTSTSEVYGTARYVPIDENHPL--QAQSPYAASKIGADQLALSFYRS- 162
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ +R FN G +S R + IP I+Q+ GR +E+++ G+ PT
Sbjct: 163 FDLPVTIIRPFNTYGPRQSAR-----AVIPT----IITQLLSGR-EEIRL-GNLAPT--- 208
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
RD+ V D G + A H G +N+G+G S+ E+V G
Sbjct: 209 ---RDFNFVEDTVNGFITAGLSPHTVG----EVVNIGSGREISIGELVELIGQLIGIKVK 261
Query: 303 XXXXXX----XXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
+V D A R GWR SL T W
Sbjct: 262 VRVDAERYRPEASEVERLCCDNRKANRLAGWRPEYSLSQGLAITIEW 308
>UniRef50_Q4HQ86 Cluster: UDP-glucose 4-epimerase, putative; n=2;
Proteobacteria|Rep: UDP-glucose 4-epimerase, putative -
Campylobacter upsaliensis RM3195
Length = 323
Score = 85.0 bits (201), Expect = 3e-15
Identities = 96/356 (26%), Positives = 152/356 (42%), Gaps = 46/356 (12%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKP-EALKRIEEL 61
+ +L+TG G++GSH L + EI + +L N++ G + E + +E +
Sbjct: 2 KKILITGADGFIGSHLCEIL-----NAKGYEIKAL-SLYNSFNFWGHLEHLECREDLEIV 55
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
+G D+R + D + + +D V+H AL A+ S P Y NI GT L
Sbjct: 56 SG--------DLRDSFFCDSLVKG--VDAVLHLGALIAIPYSYTAPQSYVDTNIQGTLNL 105
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
E ++HGV + +++S+ VYG Y PI+E HP SPY SK + + S
Sbjct: 106 LEASKRHGVKRFIHTSTSEVYGSAIYTPIDEKHPLQPQ--SPYSASKIGADMLALSYFYS 163
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
I++ R FN G +S R + IP ++ +S V +ELKV GD D
Sbjct: 164 FNLPVIVA-RPFNAYGPRQSAR-----AFIPAMMVQILSGV-----RELKV-GDLSTKRD 211
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
VRD C+ A L + F + N+G+G Y++ E++ SG
Sbjct: 212 LNFVRD---TCEGFAA------LLNNGEFGEIY--NIGSGVEYAMSEVLELICKLSGVEL 260
Query: 302 XXXXXXX----XXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
+VT + D + WR+ SL + T + + N N Y
Sbjct: 261 KISQDETRLRPKNSEVTRLLCDSSKLKSVSAWRSQISLKEGLEQTLNYIKENLNAY 316
>UniRef50_Q54WS6 Cluster: Putative dTDP-D-glucose 4,6-dehydratase;
n=1; Dictyostelium discoideum AX4|Rep: Putative
dTDP-D-glucose 4,6-dehydratase - Dictyostelium
discoideum AX4
Length = 434
Score = 84.6 bits (200), Expect = 3e-15
Identities = 89/302 (29%), Positives = 138/302 (45%), Gaps = 43/302 (14%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+L+TGGAG++GSH I L ++ + +I+V+D L YC+ LK EL K
Sbjct: 12 ILITGGAGFIGSHLAIYLTKKFKNS---KIIVLDKLD--YCSNINNLGCVLK---ELNFK 63
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
FYK +I +E L+ IFE ID VIH AA V S ++ +++ + NI GT L E
Sbjct: 64 ---FYKGNILDSELLENIFEKEKIDIVIHLAAYTHVDNSFKQSIKFTENNILGTHYLLET 120
Query: 125 MRKHGVYKLVYSSSCTVYG-------EPEYLPINESHPTGKSL--TSPYGKSKYFCEEIM 175
+ + + K +Y S+ VYG + IN+S L T+PY SK E ++
Sbjct: 121 CKNYKLKKFIYVSTDEVYGSGLIEDNDDNNNSINQSSNEKSILNPTNPYSASKAGAEHLV 180
Query: 176 KDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGD 235
+ S K II+ R N G P P ++P + + K+ + G
Sbjct: 181 QSYYKSFKLPVIIT-RANNIYG----------PKQYPEKIIPKFINLLLNN-KKCTIHG- 227
Query: 236 DYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSN 295
G R+Y+++ D+ V A + + G G + N+GT S L++ N
Sbjct: 228 -----TGKNTRNYLYIDDI----VSAFDIILRKGEIG-NVYNIGTDFEISNLDVAKKIIN 277
Query: 296 AS 297
S
Sbjct: 278 IS 279
>UniRef50_P39630 Cluster: Spore coat polysaccharide biosynthesis
protein spsJ; n=26; cellular organisms|Rep: Spore coat
polysaccharide biosynthesis protein spsJ - Bacillus
subtilis
Length = 315
Score = 84.6 bits (200), Expect = 3e-15
Identities = 91/349 (26%), Positives = 150/349 (42%), Gaps = 36/349 (10%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M+++ L+TGGAG++G T L+ R++D I V+D L+ A PE ++++++
Sbjct: 1 MAKSYLITGGAGFIGL-TFTKLMLRETDA---RITVLDKLTYA------SHPEEMEKLKQ 50
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
F K DI E +DR F+ D VIHFAA V S+ + + N+ GT
Sbjct: 51 --NSRFRFVKGDISVQEDIDRAFDE-TYDGVIHFAAESHVDRSISQAEPFITTNVMGTYR 107
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L E + K KL++ S+ VYG+ + + T S +PY SK + ++
Sbjct: 108 LAEAVLKGKAKKLIHISTDEVYGDLKADDPAFTETTPLSPNNPYSASKASSDLLVLSYVK 167
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+ K AII+ R N G ++ ++P I + A L + ++G
Sbjct: 168 THKLPAIIT-RCSNNYGPYQHS----------EKMIPTIIRHAKQGL-PVPLYG------ 209
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DG +RD++ A H +AIKL + G +G N+G G + E+ + G
Sbjct: 210 DGLQIRDWL----FAEDHCRAIKLILEKGTDG-EVYNIGGGNERTNKELASVILKHLGCE 264
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
G + + LGWR + + T +W N
Sbjct: 265 ELFAHVEDRKGHDRRYAINASKLKNELGWRQEVTFEEGIARTIQWYTDN 313
>UniRef50_Q88XK0 Cluster: UDP-glucose 4-epimerase; n=2;
Lactobacillus plantarum|Rep: UDP-glucose 4-epimerase -
Lactobacillus plantarum
Length = 315
Score = 83.8 bits (198), Expect = 6e-15
Identities = 87/341 (25%), Positives = 152/341 (44%), Gaps = 43/341 (12%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTGGAG++GSH V L+ S+G L++VVVDNLS G+ +K +E+T
Sbjct: 4 LVTGGAGFIGSHLVDHLV---SEG--LDVVVVDNLSM-----GDL--HNIKYQDEVT--- 48
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
Y D+R + + ++ + D + AA+ +V +S+E+P E + VN + E +
Sbjct: 49 --IYVEDVRNEKFMQQLLQEERPDYIYFLAAVASVADSIERPAETHSVNQTAVFNMLEYI 106
Query: 126 RKHG--VYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD- 182
RK + + +++SS VYG LP E SPY KY E + L +
Sbjct: 107 RKTNLPIKQFLFTSSAAVYGNLPELPKKEDSRVDP--LSPYAIDKYATERFV--LAYGEL 162
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ +R+FN G G++PS + ++ ++ + K ++G DG
Sbjct: 163 YDLPTVCVRFFNVYGP------GQNPSSPYSGVLSILTD-CLNNKKPFTLYG------DG 209
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
+ RD+++V D+ +QA+ L + N+ G S+ ++ + +
Sbjct: 210 SQTRDFVYVEDV----IQALWLITKSD-TEHEVFNIANGNEASLNAIIETYEKVAETSLQ 264
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTW 343
G+V +VA++ + LG+ SL W
Sbjct: 265 IKKAPGREGEVKRSVANIGKLIK-LGYTTKWSLEAGLSKYW 304
>UniRef50_Q83DA9 Cluster: NAD dependent epimerase/dehydratase family
protein; n=9; Bacteria|Rep: NAD dependent
epimerase/dehydratase family protein - Coxiella burnetii
Length = 330
Score = 83.4 bits (197), Expect = 8e-15
Identities = 91/344 (26%), Positives = 148/344 (43%), Gaps = 35/344 (10%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
+V GGAG +GSHTV LL+ D E+++ DN E +AL+ + T
Sbjct: 9 VVIGGAGLIGSHTVDRLLQE----DVAEVIIYDNFVRG---TRENLAQALR--DPRT--K 57
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
++ DI + L+ + +D V HFAAL + + E P +Q NI GT + E
Sbjct: 58 IYDIGGDINQTDILNTALKG--VDGVFHFAALWLL-QCYEYPRSAFQTNIQGTFNVLETC 114
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
GV +LV+SSS +VYG+ P+ E+HP + YG +K E M
Sbjct: 115 VAQGVKRLVFSSSASVYGDALEEPMTEAHPFNS--RTFYGATK-IAGEAMATAYHHRYGL 171
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
+ LRY N G + R G + I L A+ + + + ++G DG+
Sbjct: 172 PFVGLRYMNVYGPRQDYR-GAYIAVIMKML------DALDKGQPMTLYG------DGSQA 218
Query: 246 RDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXX 305
D+++V D AA ++ A+K + N+GTG S+LE+ +G
Sbjct: 219 YDFVYVEDCAAANICAMKADTVDEY-----YNVGTGKRTSILELAKEIQKITGTSDNIQF 273
Query: 306 XXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
V + A +G++A L + + W+ ++
Sbjct: 274 LPQGTTFVKNRIGCPKKAAEQIGFKAEVGLTEGLQRLIEWRRSH 317
>UniRef50_Q1IM02 Cluster: NAD-dependent epimerase/dehydratase; n=6;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Acidobacteria bacterium (strain Ellin345)
Length = 322
Score = 83.4 bits (197), Expect = 8e-15
Identities = 71/267 (26%), Positives = 119/267 (44%), Gaps = 20/267 (7%)
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+ F + DI A+ R + ++ V H AAL +V SV PL N+ GT L +
Sbjct: 48 MEFIEGDITDPAAVGRACDG--VEVVFHEAALASVPRSVADPLATNHANVTGTLQLLQAA 105
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
+ GV +++Y+ S + YG+ LP NE SPY SK E ++ + +
Sbjct: 106 HRAGVRRVIYAGSSSAYGDTPTLPKNEEMLANP--ISPYAVSKLTGEYYLRSM-YAVHGM 162
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
+++RYFN G ++ G SG+ L +I Q+ G + GD + D T +
Sbjct: 163 ETVTIRYFNVFGPYQDP--GSQYSGV---LAKFIPQMLRGETP--TIHGDGEQSRDFTYI 215
Query: 246 RDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXX 305
+ + ++A + A ++ + N+ TGT S+ E VA +G
Sbjct: 216 ENVVK-ANIALANAPAERVAGE-------VFNVATGTRISLNETVALLREMTGYTGAVHH 267
Query: 306 XXXXXGDVTANVADVALATRSLGWRAT 332
GDV ++AD++ A R+ G+ T
Sbjct: 268 GPERKGDVKHSLADISKAKRAFGFEPT 294
>UniRef50_Q9RWF7 Cluster: UDP-glucose 4-epimerase, putative; n=63;
cellular organisms|Rep: UDP-glucose 4-epimerase,
putative - Deinococcus radiodurans
Length = 344
Score = 83.0 bits (196), Expect = 1e-14
Identities = 84/295 (28%), Positives = 134/295 (45%), Gaps = 38/295 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
V VTG G++GSH L+ G + + + N +Y E ++ +E G
Sbjct: 19 VAVTGADGFIGSHLTEDLVRA---GYRVRAMAIYNSQGSYGWLDTVPGEVMEHVEVQLG- 74
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
D+R A ++ + + + V H AAL A+ S P Y + NI GT + E
Sbjct: 75 -------DVRDAGSVRALMRD--VQTVYHLAALIAIPYSYVAPRSYVETNITGTLNVLEA 125
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
R G +++++S+ VYG +PI+ESHP SPY +K +++ + +S
Sbjct: 126 ARDLGTGRVIHTSTSEVYGTARSVPIHESHPLQGQ--SPYSATKIGADKLAESYFLS-FG 182
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+++LR FN G +S R + IP ISQ+A GR E+K+ GD PT
Sbjct: 183 LPVVTLRPFNTYGPRQSAR-----AVIPT----IISQLAAGR-TEIKL-GDLRPT----- 226
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGF-HAINLGTGTGYSVLEMVAAFSNASG 298
RD+ +V D A +A + + G +N G+G SV + V + G
Sbjct: 227 -RDFNYVADTA----RAFRAVGEAGPEVLGRTLNAGSGREISVGDTVKLIAQVMG 276
>UniRef50_A0FWU5 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Betaproteobacteria|Rep: NAD-dependent
epimerase/dehydratase - Burkholderia phymatum STM815
Length = 310
Score = 83.0 bits (196), Expect = 1e-14
Identities = 91/343 (26%), Positives = 148/343 (43%), Gaps = 44/343 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+ V GG G++GS V LL DN + C + + ++ + G+
Sbjct: 3 ITVFGGGGFIGSTIVDRLLR-------------DN--HEICVFERPRVDPYRQFND--GE 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
VH+ D+ + + +I V+H + S + P+ Q N+ T L
Sbjct: 46 KVHWMTGDLTSVHDVTEAIDGSDI--VVHLVSTTLPKSSNDDPIYDVQSNLVATLQLLNA 103
Query: 125 MRKHGVYKLVY-SSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
M V K+V+ SS TVYG+P YLPI+E HPT ++ YG +K E+ +
Sbjct: 104 MVAKNVKKIVFISSGGTVYGDPVYLPIDEKHPTNPKVS--YGITKLAIEKYLLLYQYQHG 161
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
A I LR NP G E R+ E G + ++ + R + +++G DGT
Sbjct: 162 IKANI-LRVANPYG--ERQRV-ETAQGA---IAVFLDKAL--RKQPFEIWG------DGT 206
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAI-NLGTGTGYSVLEMVAAFSNASGXXXX 302
RDY+++ D+A +A++ ++G ++ N+ +G G S+ E++ G
Sbjct: 207 VTRDYLYIGDVAEAFARAVQ------YDGNESVFNISSGYGTSLNEIIGKIETILGHPVE 260
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
DV A+V D LA R LGW +L + T W
Sbjct: 261 RTYRPGRPFDVPASVLDNTLAKRELGWEPKVALDAGIKLTATW 303
>UniRef50_A7D7X9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: NAD-dependent
epimerase/dehydratase - Halorubrum lacusprofundi ATCC
49239
Length = 315
Score = 82.6 bits (195), Expect = 1e-14
Identities = 93/333 (27%), Positives = 147/333 (44%), Gaps = 49/333 (14%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGGAG++GSH V L ++ V+D+ C+ G + A+ LT
Sbjct: 19 VLVTGGAGFIGSHLVDAL------APVADVHVLDD-----CSTGRQT--AVHGDATLTVG 65
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ ++ A+A+ D V H AA+ +V ++ P VN++ T L ++
Sbjct: 66 DITDHET---LADAVA------GTDYVFHLAAISSVPGAMADPPRALDVNVSATADLLDL 116
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
G ++V++SS VYG+P +PI E+ K PYG SK + +++ K
Sbjct: 117 ATDAGA-RVVFASSAAVYGDPSSVPIGET--DAKDPREPYGVSKLAGDHLVRGY-ADWKD 172
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
++LR FN G ++G G PS ++ QV G + L V G DGT
Sbjct: 173 LDTVALRLFNVYGPGQTG--GVVPS--------FLEQVQRG--EPLVVHG------DGTQ 214
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RD++HV D+ V A + G + N+GTG S+ E+ +A+
Sbjct: 215 TRDFVHVDDVVRAMVAAART-DATG----ESFNVGTGDVTSIHELATVVRDAAPVTVDVV 269
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHD 337
DV + AD A R L + A ++ D
Sbjct: 270 HDDPRPADVPESQADTTKARRDLEFEARTTVED 302
>UniRef50_A6PTX1 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Victivallis vadensis ATCC BAA-548|Rep: NAD-dependent
epimerase/dehydratase - Victivallis vadensis ATCC
BAA-548
Length = 305
Score = 81.4 bits (192), Expect = 3e-14
Identities = 90/317 (28%), Positives = 138/317 (43%), Gaps = 45/317 (14%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VL+TGGAG++GSH + G E+ ++D+L + + KK L G
Sbjct: 3 VLITGGAGFIGSH-----IAEYFQGKA-EVRILDSLRSGF-----KK--------NLDGL 43
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V F + DIR + + E+ +D V H AA+ +V ES+ K +E +N G + E
Sbjct: 44 DVEFIEGDIRDRITVAKAMED--VDYVFHLAAMISVPESMTKIIECIDINNTGMLIVLEE 101
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLP-INESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
K GV KL +S+S +YG+ +P + P KS PY +K E K +
Sbjct: 102 AAKAGVKKLCFSTSAAIYGDNPVVPKVETMFPEPKS---PYAITKLDGEYYCK-MFNDTG 157
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
K LRYFN G + DP +P + AV + L +FGD G
Sbjct: 158 KLKTACLRYFNVFGPRQ------DPKSAYAAAVPIFTAKAVAN-EPLTIFGD------GE 204
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RD+I+V D+ A +V H F+G + N+ G ++ ++ +G
Sbjct: 205 QTRDFIYVKDIVAANV--FMATHD--FSGVY--NVAYGGKITINDLAKEIIRLTGSKSEI 258
Query: 304 XXXXXXXGDVTANVADV 320
GDV ++A V
Sbjct: 259 QYLPERIGDVKHSMAAV 275
>UniRef50_A6GG02 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 313
Score = 81.4 bits (192), Expect = 3e-14
Identities = 96/347 (27%), Positives = 139/347 (40%), Gaps = 43/347 (12%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
MSR +LVTGGAG++G+ T + + V+D+LS E L IE
Sbjct: 1 MSR-LLVTGGAGFIGAQVCATAIAAG-----YTVRVLDDLSTGL----RSNLEGLPGIEL 50
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
L G ++ C E R ++D VIH AA +V S++ P + N+ GT
Sbjct: 51 LVGDIR-----ELACCEHAVR-----DVDAVIHLAARGSVPRSIDDPQATMRTNVMGTTN 100
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
+ + R+ GV ++V SSS ++YG LP E SPY SK E + +
Sbjct: 101 VLDACRRAGVRRVVQSSSSSIYGVVPGLPRREQQRPDP--RSPYAASKLAAEHVAQ---A 155
Query: 181 SDKKWA--IISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYP 238
W +++LR FN G + S + +I+ GR EL
Sbjct: 156 WHACWGVEVVTLRLFNVYGPRQ-----RSDSSYAAVVPLFIAAALSGRPAELH------- 203
Query: 239 TADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
G R + +V D+A G + A++ P INL V E+ A G
Sbjct: 204 -GGGEQSRAFTYVEDVAEGILAALR---SPRVGENERINLAHEACEPVRELHARIGALVG 259
Query: 299 XXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV ++ AD+ A LGW A SL T W
Sbjct: 260 VDIPPRITAARRGDVLSSSADLERARTLLGWTAQTSLDAGLAATIAW 306
>UniRef50_A0K2B4 Cluster: NAD-dependent epimerase/dehydratase; n=10;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Arthrobacter sp. (strain FB24)
Length = 331
Score = 81.4 bits (192), Expect = 3e-14
Identities = 95/343 (27%), Positives = 149/343 (43%), Gaps = 39/343 (11%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGGAG +GS T+++ I V+DNL A + A R+E + G
Sbjct: 9 VLVTGGAGTIGS----TIVDHLVTAGVERITVLDNLVRGRRANLDDAV-ATGRVELVEG- 62
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
D+R + + + +I V H AA++ + + E+P +V ++GT +FE
Sbjct: 63 -------DLRDRDLVHDLTRGKDI--VFHQAAIR-ITQCAEEPRLALEVLVDGTFNVFEA 112
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+HGV KLV +SS +VYG E P +E H + T YG +K F E + +
Sbjct: 113 AAEHGVGKLVAASSASVYGMAEEFPTSERHHHHNNDTF-YGAAKSFNEGMARSFRAMTGL 171
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNN-LMPYISQVAVGRLKELKVFGDDYPTADGT 243
++ LRYFN G D G+ L+ ++ ++A G + +FG DG
Sbjct: 172 DYVL-LRYFNVYGPR------MDVHGLYTEVLVRWMERIADG--QPPLIFG------DGR 216
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNA-SGXXXX 302
D+IH D+A ++ A + G N+ +G S+L++ A A
Sbjct: 217 QTMDFIHTRDVARANILAAGSGAREG-----VYNVASGEETSLLQLAEALLRAMDSELHV 271
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
V +AD + A LG+ A L D R+ W
Sbjct: 272 EHGPDRAINGVVRRLADTSAARLDLGFAAETGLEDGLRELVDW 314
>UniRef50_A2GEF2 Cluster: NAD dependent epimerase/dehydratase family
protein; n=2; Trichomonas vaginalis G3|Rep: NAD
dependent epimerase/dehydratase family protein -
Trichomonas vaginalis G3
Length = 348
Score = 81.4 bits (192), Expect = 3e-14
Identities = 92/346 (26%), Positives = 141/346 (40%), Gaps = 42/346 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+L+TGGAG++GSH L+ + D ++I+ +D + YCA L+ +EE+ K
Sbjct: 10 ILLTGGAGFIGSHVCNHLVLKYPD---VKIICLDVMD--YCAN-------LRNLEEIMNK 57
Query: 65 -TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
F K I E + I + H +D V+HFAA V S LE+ NI GT L E
Sbjct: 58 PNFLFIKGSINNVELVSYIMKTHAVDTVMHFAAQSHVDRSFGNSLEFTHTNILGTHVLLE 117
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+++ + + ++ S+ VYGE E + T+PY SK E M +
Sbjct: 118 CAKQNNIKRFIHVSTDEVYGE-VLSGCAEEEKSILCPTNPYACSKAGA-EFMCQAYIRSF 175
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
II R N G P P ++P + + LK DG+
Sbjct: 176 NMPIIITRGNNVFG----------PKQFPEKVIPKFTLL-------LKAGHKCCIHGDGS 218
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAI-NLGTGTGYSVLEMVAAFSNASGXXXX 302
+R+++H D+ VQA G H I N+GT SVLEM
Sbjct: 219 ALRNFLHTSDV----VQAFDTILHKG--KLHQIYNIGTDFEISVLEMTKKLIKVLNMPGK 272
Query: 303 XXXXXXXXGDVTANVADVALATR---SLGWRATRSLHDMCRDTWRW 345
D N + + + +LGW A + ++T +W
Sbjct: 273 PEDWIEFVPDRAFNDSRYMINSSKLIALGWHANTDFDTLLKETVQW 318
>UniRef50_Q97CP3 Cluster: NDP-sugar epimerase; n=4;
Thermoplasmatales|Rep: NDP-sugar epimerase -
Thermoplasma volcanium
Length = 312
Score = 81.4 bits (192), Expect = 3e-14
Identities = 84/292 (28%), Positives = 137/292 (46%), Gaps = 46/292 (15%)
Query: 2 SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL 61
++ +L+TGGAG++GS+ V LL + E+ V+DNLS +K+ +
Sbjct: 3 NKRILITGGAGFIGSNMVEHLLPKN------EVTVIDNLSIT-------DDRYIKKFYD- 48
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
F K DI L+ I + ++ D V+H AA V P +VN+ GT ++
Sbjct: 49 -NPNFKFIKKDI-----LNGI-DGYHYDIVVHLAADSDVRNGSSNPALDMKVNVEGTISV 101
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
E+MRK + ++++SS TVYGE + +P E++ ++S YG SK E + S
Sbjct: 102 LEMMRKSDIKDILFASSSTVYGEAKVIPTPENYGPLLPISS-YGASKLAAEAFI-SAYAS 159
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+ + R+ N VG + + + + +I+++ + KEL+V G D
Sbjct: 160 YYGFNALLFRFANVVGKNSTHGV----------IFDFINKLKNNK-KELEVLG------D 202
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAF 293
GT + YIHV DL + + H G F NLG SV + +A F
Sbjct: 203 GTQAKSYIHVEDLIGSMIYVYE--HVKGVEPF---NLGNDDVTSV-DKIAKF 248
>UniRef50_Q12VP0 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Methanococcoides burtonii DSM 6242|Rep: NAD-dependent
epimerase/dehydratase - Methanococcoides burtonii
(strain DSM 6242)
Length = 303
Score = 81.4 bits (192), Expect = 3e-14
Identities = 59/201 (29%), Positives = 97/201 (48%), Gaps = 27/201 (13%)
Query: 89 DCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEYL 148
D ++H A + + ES P + Y +N GT + E R + V + +Y+S+ VYG P+Y
Sbjct: 62 DVLVHLAGMTNIPESFNHPRDVYTINTFGTLNMLEWCRLNDVKRFIYASTF-VYGNPQYT 120
Query: 149 PINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDP 208
P++E HPT + +PY +SK EE+ C D +ISLR FN G H+ G
Sbjct: 121 PVDEKHPTLPN--NPYSQSKLIGEELCNAYC-RDYGIDVISLRLFNVYGPHQKG------ 171
Query: 209 SGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQP 268
+ L+P+I + +L+ KV D RD++++ D+ + + +
Sbjct: 172 ----DYLIPHI----IRQLESGKV-----SLKDPLPKRDFVYIDDV----IDSFECALDS 214
Query: 269 GFNGFHAINLGTGTGYSVLEM 289
G G + N+ G SV E+
Sbjct: 215 GLGGCNVFNIANGKSNSVREI 235
>UniRef50_A3PV39 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=1; Mycobacterium sp. JLS|Rep: NAD-dependent
epimerase/dehydratase precursor - Mycobacterium sp.
(strain JLS)
Length = 324
Score = 81.0 bits (191), Expect = 4e-14
Identities = 95/356 (26%), Positives = 148/356 (41%), Gaps = 42/356 (11%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDP-LEIVVVDNLSNAYCAEGEKKPEALKR--IE 59
+ VL+TG AG+VGS TL ER DP +E++ +D ++ Y P+++K +E
Sbjct: 2 KRVLITGIAGFVGS----TLGERLIANDPSIEVIGIDRYTDYY-------PKSIKEANLE 50
Query: 60 ELTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLE-YYQVNINGT 118
L V DI A LD + + +D V H A V S + Y + NI +
Sbjct: 51 VLREYGVRILDEDILEAN-LDNLLDG--VDVVFHQAGQPGVRRSWGDSFDAYLRDNILAS 107
Query: 119 CTLFEIMRKH-GVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKD 177
L E R+ + + VY+SS +VYG+ E P E+ SPYG +K E +M
Sbjct: 108 QRLLEAARRSTSLRRFVYASSSSVYGDAERYPTLETDTPQPR--SPYGVTKLAAEHLM-G 164
Query: 178 LCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDY 237
L + +SLRYF G + + +I++ GR +++FG
Sbjct: 165 LYAQNFGVPTLSLRYFTVFGPRQRPDMA---------FTRFIARTLAGR--PIEIFGS-- 211
Query: 238 PTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNAS 297
G +RD+ V D+ + ++ A G N+ G +V E++A
Sbjct: 212 ----GEQIRDFTFVDDVVSANLAAATA---AGVLPGTVYNISGGASVTVNEILATLEEIL 264
Query: 298 GXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
GDV A R +GW T SLH+ R W +++ Y
Sbjct: 265 DGPILTHRAETVAGDVFRTGGSNEAARRGIGWEPTVSLHEGLRRQVEWLQSHRERY 320
>UniRef50_Q1IKI6 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Acidobacteria bacterium Ellin345|Rep: NAD-dependent
epimerase/dehydratase - Acidobacteria bacterium (strain
Ellin345)
Length = 332
Score = 80.6 bits (190), Expect = 6e-14
Identities = 82/288 (28%), Positives = 126/288 (43%), Gaps = 41/288 (14%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
L+TGGAG++GSH LL R GD E+ ++D+LS + I+ L
Sbjct: 4 LITGGAGFIGSHLAEKLLSR---GD--EVHIIDDLSTG----------TIANIQHLKSSP 48
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+ Y +D + L + D H AA V VE P+ + NI GT + +
Sbjct: 49 LFHYHIDTITNQRLMTELVD-LCDITYHLAAAVGVRLIVESPVRTMETNIRGTEIVLALA 107
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV----S 181
+ L+ S+S VYG+ E++P E TS G+ Y C + + +
Sbjct: 108 ERKRKRVLITSTS-EVYGKREHIPFREDDDLIMGPTSK-GRWSYACSKAIDEFLAIAYWK 165
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+KK + +R FN VG ++GR G IPN ++Q G +++ VFG D
Sbjct: 166 EKKVPTVIVRLFNTVGPRQTGRYG---MVIPN----LVTQALTG--EDMTVFG------D 210
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEM 289
G R + HV D VQ + P NG N+GT ++L++
Sbjct: 211 GLQARCFTHVSDSVNSIVQ---IAAHPNANG-EVYNIGTQEEITILDL 254
>UniRef50_Q9UXJ4 Cluster: DTDP-glucose 4,6-dehydratase; n=2;
Sulfolobaceae|Rep: DTDP-glucose 4,6-dehydratase -
Sulfolobus solfataricus
Length = 310
Score = 79.8 bits (188), Expect = 1e-13
Identities = 94/351 (26%), Positives = 148/351 (42%), Gaps = 53/351 (15%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKR-IE 59
M +L++GGAG++GSH LLE+ G+ EI +VD+LS A K E +K+ +E
Sbjct: 1 MLMKILISGGAGFLGSHLTEALLEK---GE--EITIVDDLSTAKYFNIRKDVEFIKKKVE 55
Query: 60 ELTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTC 119
E +T Y D VIH AA + + +E P++ N GT
Sbjct: 56 EF--ETEKKY-------------------DVVIHLAARPSPEDYIEHPVDTALSNSLGTY 94
Query: 120 TLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESH-----PTGKSLTSPYGKSKYFCEEI 174
+ EI RK + +Y+SS VYG +P E++ P G + S Y +SK F E
Sbjct: 95 KMLEIARKSNA-RFIYTSSSEVYGSASIIPTPETYWGYVNPIG--IRSCYDESKRFSEA- 150
Query: 175 MKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFG 234
L ++ + + R P + G + ED + + +I Q G +++ VFG
Sbjct: 151 ---LIMAYHRQYKLDTRIQRPFNVYGPG-LREDGT-YGRVVSRFIYQALKG--EDVTVFG 203
Query: 235 DDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFS 294
DG R ++++ D IKL ++ G G N+G+ ++E+
Sbjct: 204 ------DGNQTRAFLYISDWVDA---TIKLIYKDGLEG-EVFNIGSDKEIKIIELANMII 253
Query: 295 NASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
+G D AD+ A LGW SL + + T W
Sbjct: 254 KLTGSKSRIKYLPPRPDDPPRRAADITKAKEKLGWYPKISLEEGLKLTINW 304
>UniRef50_A1Y020 Cluster: UDP-glucose 4-epimerase; n=1; Spironucleus
barkhanus|Rep: UDP-glucose 4-epimerase - Spironucleus
barkhanus
Length = 306
Score = 79.4 bits (187), Expect = 1e-13
Identities = 91/355 (25%), Positives = 152/355 (42%), Gaps = 59/355 (16%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
+VL+TGGAG++GSH V + ++ V+DN + TG
Sbjct: 2 SVLITGGAGFIGSHFVSFFASKG-----YKVTVLDNFA--------------------TG 36
Query: 64 KTVHF---YKV-DIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTC 119
+ +H Y V D+ A D + D V+H AA +V ES+ P +Y + + G+
Sbjct: 37 RNLHADATYVVGDVTDTSAFDTL---STFDFVVHLAAAISVAESMTNPAKYQRSIVEGSR 93
Query: 120 TLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC 179
+F + G ++ +SS VYG+ I E++ G SPY ++KY E I
Sbjct: 94 NVFAYAVRTGARAVLSASSAAVYGDCGTDAITEAYRYGG--ISPYAQAKYDMEGIPAGDT 151
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+ + I R+FN G + DPS +M A+ + + +FGD
Sbjct: 152 SATR---FIFCRFFNVFGPRQ------DPSSPYTGVMSIFIDRALRGIP-ITIFGD---- 197
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
G RD+++V DL G A L G +G N+GTG +V + ++ G
Sbjct: 198 --GEQTRDFVYVKDLVCG---AFALL-DGGASG--VFNIGTGRSTAVQRLAEICADLGGS 249
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW-QEANPNGY 353
GD+ +++ ++GWRA D + TW+W ++ + +G+
Sbjct: 250 EIVHAEPRD--GDIKYSLSCPEKIFETVGWRAETEFLDGLKATWQWAKDGDSDGF 302
>UniRef50_UPI0001597DB3 Cluster: SpsJ; n=1; Bacillus
amyloliquefaciens FZB42|Rep: SpsJ - Bacillus
amyloliquefaciens FZB42
Length = 315
Score = 79.0 bits (186), Expect = 2e-13
Identities = 92/347 (26%), Positives = 153/347 (44%), Gaps = 40/347 (11%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M ++ L+TGGAG++G T ++ +++D +I V+DNL+ A + EALK+
Sbjct: 1 MPKSYLITGGAGFIGL-TFTKMMLKETDA---QITVLDNLTYA---SRPLEIEALKK--- 50
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
G+ F K DI E +D++F + D VIHFAA V S+ + + N+ GT
Sbjct: 51 -NGR-FRFIKGDISEKEDIDKVF-SQMYDAVIHFAAESHVDRSINQAEPFITTNVMGTYR 107
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGE--PEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL 178
L + + + +L++ S+ VYG+ P+ E+ P S +PY SK + ++
Sbjct: 108 LADAVLQGKAGRLIHISTDEVYGDLAPDDPAFTETTPL--SPNNPYSASKASSDLLVMSY 165
Query: 179 CVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYP 238
+ K AII+ R N G ++ ++P I + AV + ++G
Sbjct: 166 VRTHKLPAIIT-RCSNNYGPYQH----------HEKMIPTIIRHAVNG-TPVPLYG---- 209
Query: 239 TADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
DG +RD++ A H +AIKL + G G N+G G + E+ + G
Sbjct: 210 --DGMQIRDWL----FAEDHCRAIKLVLEKGTLG-DIYNIGGGNERTNKELASFIMKELG 262
Query: 299 XXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
G + + LGWR + + R T RW
Sbjct: 263 VEERFAHVEDRKGHDRRYAINASKLKNELGWRQDVTFEEGMRRTIRW 309
>UniRef50_Q868I5 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=2;
Giardia intestinalis|Rep: UDP-N-acetylglucosamine
4-epimerase - Giardia lamblia (Giardia intestinalis)
Length = 385
Score = 79.0 bits (186), Expect = 2e-13
Identities = 87/362 (24%), Positives = 139/362 (38%), Gaps = 43/362 (11%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
+ + VL+TGG G++GSH V + + V+DNLS+ K +
Sbjct: 7 LGKTVLITGGCGFIGSHFV-----EACHVLGMTVYVLDNLSSG--------KNVFKTTSD 53
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+ V+ DIR R+ + ID VIH AA +V ESV P +Y N+ G+
Sbjct: 54 CSSSLVYTIG-DIRDKAIFSRLPQK--IDFVIHLAAAVSVAESVTNPQKYMLTNVEGSRN 110
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
+F+ ++ +S+ YG+ I E+ P G SPY +SK E + +
Sbjct: 111 VFQYAVDAKASAVLSASTAAYYGDCGKSAITEAFPYGG--ISPYAESKMEMERLGAEF-Q 167
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+ I R+FN G +DPS +M R K + +FG T
Sbjct: 168 KTSRCRFIFCRFFNVYGPR------QDPSSPYTGVMSIFMDRCAAR-KPITIFGTGEQTR 220
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKL------------FHQPGFNGF----HAINLGTGTGY 284
D ++D I G + + + + G N+G+G
Sbjct: 221 DFVFIKDLIVAAINLLGQLDKFPIGADAVQQNDPEEVQRSAYTGEGVYPTVFNIGSGISI 280
Query: 285 SVLEMVAAFSNASGXXXXXXXXXX-XXGDVTANVADVALATRSLGWRATRSLHDMCRDTW 343
SV E+ SG GD+ +++D + GW A+ +L +TW
Sbjct: 281 SVNELAELAKIVSGRHEVEIVHGEPRSGDILHSLSDCTRIRNATGWSASTTLRVGMSETW 340
Query: 344 RW 345
W
Sbjct: 341 GW 342
>UniRef50_Q3JAZ5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Nitrosococcus oceani ATCC 19707|Rep: NAD-dependent
epimerase/dehydratase - Nitrosococcus oceani (strain
ATCC 19707 / NCIMB 11848)
Length = 320
Score = 78.6 bits (185), Expect = 2e-13
Identities = 87/342 (25%), Positives = 145/342 (42%), Gaps = 45/342 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGG G++G + + LL+ + ++ V+DNL A P + +
Sbjct: 7 ILVTGGRGFIGVNLIQPLLQSR------DVRVLDNLQRA-------SPTGWQN------Q 47
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F++ D+ +L F + + VIH AA +V ESV P + VN++GT +
Sbjct: 48 AADFFQGDVLEPGSLVPAFTD--VPKVIHLAAYGSVVESVADPTSNFAVNVHGTLNVMNA 105
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+ GV +L+++S+ P++E K + SPYG SK C E
Sbjct: 106 AVEAGVERLIFASTGGALIGDATPPVDE-RSLPKPI-SPYGASK-LCGEAYCHAFAKSYH 162
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+ LR+ N G H + + G + I A+ + + + ++G DG+
Sbjct: 163 LETVCLRFGNVYGPHSAHKKGAVTTFIK----------ALMKDEPIVIYG------DGSA 206
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX-XXXX 303
RDYIHV DL +G A+++ G +L +G +VLE+ +G
Sbjct: 207 SRDYIHVEDLGSGIAAALEV----PVEGSETFHLASGRETTVLELADILRQVAGKPHHPI 262
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
G+V+ N A A + G++ L D TW W
Sbjct: 263 HFKAARRGEVSRNFATYEKARCAFGFKPKWRLEDGLAATWEW 304
>UniRef50_Q41C61 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=1; Exiguobacterium sibiricum 255-15|Rep:
NAD-dependent epimerase/dehydratase precursor -
Exiguobacterium sibiricum 255-15
Length = 306
Score = 78.6 bits (185), Expect = 2e-13
Identities = 91/341 (26%), Positives = 147/341 (43%), Gaps = 46/341 (13%)
Query: 7 VTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKTV 66
+TGGAG++G+ + L Q+ G + V+D ++ Y E + L R ++L +
Sbjct: 5 ITGGAGFIGAALALRL---QASGHTVH--VIDAFTDYYDVELK-----LTRAKQLQANGI 54
Query: 67 HFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMR 126
+ ++ E L NH+ + H AAL V S+ +P Y + +I T T+ E R
Sbjct: 55 DVFDGNVH--EDLATWCANHSFAALFHLAALPGVPGSLTEPHRYIEDDIAMTVTVLEAAR 112
Query: 127 KHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL-CVSDKKW 185
HG+ + ++SS +VYGE + + E TG ++ SPY +KY E + + D
Sbjct: 113 THGIPHVFFASSSSVYGE-QTGALLEQQATG-NVMSPYAAAKYSAETFCRTYHNLYDMNV 170
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPN-NLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
I R+F G PSG P+ L +I Q G + L VFGD
Sbjct: 171 TI--FRFFTVYG----------PSGRPDMALFRFIEQALDG--QPLTVFGDP-------- 208
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
VRD+ ++ D+ G QA++ NLG SV ++ A S
Sbjct: 209 VRDFTYIDDITRGMEQALEA------KATGIFNLGANRPESVRDLAAMLSER--FNVPVR 260
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV+ ++ A ++ G+ + +L D RW
Sbjct: 261 SAPARIGDVSMTWSNTDAARQTFGYVPSFTLADGIEQMIRW 301
>UniRef50_Q1VGF9 Cluster: Putative uncharacterized protein; n=1;
Psychroflexus torquis ATCC 700755|Rep: Putative
uncharacterized protein - Psychroflexus torquis ATCC
700755
Length = 268
Score = 78.6 bits (185), Expect = 2e-13
Identities = 62/206 (30%), Positives = 102/206 (49%), Gaps = 21/206 (10%)
Query: 91 VIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPI 150
V+H AA +V +S+E P E ++N+ GT L +GV + V +SS VYG + P+
Sbjct: 22 VVHLAAQVSVPQSMEFPKETLEINVGGTDNLLNSCNINGVSRFVLASSAAVYGTNDAFPL 81
Query: 151 NESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSG 210
+ES + SPY SK+ E+ + L + ++LR+FN G G+ G
Sbjct: 82 DES--DAGAFHSPYADSKWQNEQ--QVLKAKEAGMEAVALRFFNVYGT------GQRADG 131
Query: 211 IPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGF 270
++P ++AVG + +FG DG RD++HV D+A + L +P
Sbjct: 132 AYAAVIPKFIELAVGG-RAPTIFG------DGLQTRDFVHVDDVAQA---LLLLATEPWT 181
Query: 271 NGF-HAINLGTGTGYSVLEMVAAFSN 295
+ F H N+ T T S+L++++ N
Sbjct: 182 DEFEHVYNVCTQTEISLLDLLSTIHN 207
>UniRef50_A7HFB5 Cluster: NAD-dependent epimerase/dehydratase; n=2;
cellular organisms|Rep: NAD-dependent
epimerase/dehydratase - Anaeromyxobacter sp. Fw109-5
Length = 373
Score = 78.6 bits (185), Expect = 2e-13
Identities = 53/146 (36%), Positives = 77/146 (52%), Gaps = 16/146 (10%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKR-IEEL 61
+ +LVTGGAG++GSH LLER + +D+LS E ++P+ L +E L
Sbjct: 4 KLILVTGGAGFIGSHLADQLLERG-----YRVRALDDLSPQVHGENARRPDYLSEGVELL 58
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
G D+R +A+ R E +D V+H AA VG+S+ + Y VN GT L
Sbjct: 59 LG--------DVRDPDAVSRALEG--VDAVVHLAARVGVGQSMYEVERYVSVNGVGTAVL 108
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEY 147
E + K V +LV +SS ++YGE Y
Sbjct: 109 LEALIKRPVERLVVASSMSIYGEGLY 134
Score = 41.5 bits (93), Expect = 0.032
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DG RD++HV D+A + A++ G A+N+G+G ++V E+ + A G
Sbjct: 247 DGLQRRDFVHVQDVARACLLALEAPEAAGL----ALNVGSGRSFTVREIAERLATALGEE 302
Query: 301 XX--XXXXXXXXGDVTANVADVALATRSLGW 329
GD+ ADV+LA R LG+
Sbjct: 303 RIVPEITGRYRAGDIRHCFADVSLARRVLGY 333
>UniRef50_A6CLM3 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus sp.
SG-1|Rep: UDP-glucose 4-epimerase - Bacillus sp. SG-1
Length = 306
Score = 78.6 bits (185), Expect = 2e-13
Identities = 93/339 (27%), Positives = 148/339 (43%), Gaps = 46/339 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGG G++GS+ V +L+E ++V+VD+ + G K K
Sbjct: 3 ILVTGGNGFIGSYVVNSLVE-----GGYKVVIVDS------SIGNKNS---------INK 42
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V Y+++I + L +F+ D VIH AA V SV +P+ +VNI GT +
Sbjct: 43 KVKCYQLNIT-DKNLSNVFDKERPDAVIHMAAQVDVSRSVMEPIMDAEVNILGTINVLNE 101
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC-VSDK 183
K+ V K+VYSS+ VYGE I+E+ S YG SKY E ++ +
Sbjct: 102 CVKYKVKKVVYSSTSAVYGENVASEISENEKI--MPISFYGISKYTPELYLEAFFKIHGL 159
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
K+ I LRY N G + G GE G+ + +I ++ R +FG DG
Sbjct: 160 KYTI--LRYSNVYGERQ-GIKGE--GGV---IPIFIHELMEDR--SPVIFG------DGK 203
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
RD+I+ D+A +V A+ +N+ +G ++L++ + G
Sbjct: 204 QTRDFIYAGDVAEANVSALNA------ADMEVLNISSGISITILQLFEQIRDLMGKAVTP 257
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDT 342
GD+ + + A L W +L + R T
Sbjct: 258 NFRGGRSGDILHSRLANSKAIMMLSWEPKVNLPEGLRKT 296
>UniRef50_A0LKC0 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: NAD-dependent
epimerase/dehydratase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 312
Score = 78.2 bits (184), Expect = 3e-13
Identities = 99/351 (28%), Positives = 145/351 (41%), Gaps = 51/351 (14%)
Query: 1 MSRAV--LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRI 58
MS A+ L+TGGAG++G++ + R+ + I V+DNLS R
Sbjct: 1 MSLAIVYLITGGAGFIGTNLI-----RRLSIPSVRIRVLDNLSAG-------------RR 42
Query: 59 EELTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGT 118
E+L G V F + DI+ A A+ R VIH AA V +SV P VN+ GT
Sbjct: 43 EDLDGFDVEFVQGDIQDAGAVHRAVAGARK--VIHLAANTNVVQSVANPELNLDVNVRGT 100
Query: 119 CTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL 178
L +HGV + V++S+ P++E P SPYG SK E
Sbjct: 101 FNLLRASVEHGVERFVFASTGGAIVGDVTPPVHEDMPPNP--ISPYGASKLAGEGYCSAF 158
Query: 179 CVSDKKWAIISLRYFNPVG--AHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDD 236
+SLR+ N G ++ G + + + +V G K L ++G
Sbjct: 159 W-GAYGLPTVSLRFSNIYGPFSYHKGSV----------IAKFFREVQAG--KPLTIYG-- 203
Query: 237 YPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNA 296
DG RD++ V DL G +A++ F G +I LG+G +V MVA A
Sbjct: 204 ----DGEQTRDFLFVGDLCQGIARALEA--PLPFGG--SIQLGSGRETTVNSMVALMREA 255
Query: 297 SGXXXX--XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
G G+V N A A + L + L +TW+W
Sbjct: 256 VGGDWFPPVTYAPPRAGEVLRNYVSTARAEKYLDFSPATDLPSGLTETWKW 306
>UniRef50_O26480 Cluster: UDP-glucose 4-epimerase homolog; n=3;
cellular organisms|Rep: UDP-glucose 4-epimerase homolog
- Methanobacterium thermoautotrophicum
Length = 316
Score = 78.2 bits (184), Expect = 3e-13
Identities = 92/345 (26%), Positives = 145/345 (42%), Gaps = 50/345 (14%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
V VTGG G++GSH LLER + + V+D+LS P+ L+ +
Sbjct: 6 VAVTGGLGFIGSHLTDELLERGN-----RVTVIDDLSTG-------SPDNLRDPHH---E 50
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ + I + L+++F+ D V H AAL +V ESV PL ++VN GT +
Sbjct: 51 DLEIIEGSINDLD-LEKVFQGK--DYVFHQAALASVPESVRDPLRCHRVNATGTLRVLMA 107
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSK----YFCEEIMKDLCV 180
+ GV K+V +S+ VYG +P+ E SPY SK Y+C+
Sbjct: 108 SSRAGVRKVVNASTSAVYGNNPEIPLRED--ARPMPLSPYAVSKVTGEYYCQ------VF 159
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
D+ +SLRYFN G + + + IP +I + GR E ++G
Sbjct: 160 EDQGLETVSLRYFNVYGPRQRPD-SQYAAVIPR----FIDALLSGRSPE--IYG------ 206
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
DG RD+I+V D+ ++ + G N+ G+ +V + S
Sbjct: 207 DGEQSRDFIYVGDVVRANIFLAE------SRGSGVYNVAGGSSVTVNRLFDIISGILESD 260
Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
GDV ++AD + + G+R L + T W
Sbjct: 261 AEPEYLDERPGDVRHSLADTS-RLAAAGFRPEVGLEEGLMRTVEW 304
>UniRef50_A6GE58 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=1; Plesiocystis pacifica SIR-1|Rep:
NAD-dependent epimerase/dehydratase family protein -
Plesiocystis pacifica SIR-1
Length = 360
Score = 77.8 bits (183), Expect = 4e-13
Identities = 95/357 (26%), Positives = 150/357 (42%), Gaps = 35/357 (9%)
Query: 3 RAVLVTGGAGYVGSHTVITLL---ERQSDGDPLEIVVVDNLSNAYC-AEGEKKPEALKRI 58
R L+TG AG++GSH LL +R D + DNL A G E
Sbjct: 16 RTWLITGVAGFIGSHLAEHLLALGQRVVGVDNFDTGKRDNLDALVRGAVGRGACEVEAHF 75
Query: 59 EELTGKTVHFYKVDIRCAEALDRIFENHN-IDCVIHFAALKAVGESVEKPLEYYQVNING 117
E F ++D+R EAL + + ++ V+H AA+ +V ++ +P + VN++G
Sbjct: 76 E--------FRELDVRDPEALRQACARFDGVEHVLHHAAVASVPRTLAEPETAHSVNVDG 127
Query: 118 TCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHP---TGKSLTSPYGKSKYFCEEI 174
L E R G +V+++S VYG+ P + G+ L SPY K E+
Sbjct: 128 MFNLLEAARACGAKSVVHATSSAVYGDCPGAPETGAQSEAIIGRPL-SPYAGQKRIA-EV 185
Query: 175 MKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVF 233
+ + +++ LRYFN VG +DP+G ++P +I +A G ++ +F
Sbjct: 186 LGQTWSTTHGMSVVGLRYFNIVGPR------QDPNGAYAAVIPKWIDTLARG--EQPVIF 237
Query: 234 GDDYPTADGTGVRDYIHVCDLAA-GHVQA-IKLFHQPGFNGFHAINLGTGTGYSVLEMVA 291
GD T D V D + LA+ H +A PG N+G G ++LE+
Sbjct: 238 GDGLTTRDFCPVEDVVQANLLASTWHERADADARAMPGDPSEGVFNVGLGGRLTLLELFE 297
Query: 292 AFSNASG------XXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDT 342
+ GD+ + ADV+ A LG+ L R T
Sbjct: 298 LLRDGMADRGVDCRAMQPRHEDFRAGDIRHSRADVSRARELLGYEPAMPLDTSLRAT 354
>UniRef50_A5WE41 Cluster: NAD-dependent epimerase/dehydratase; n=5;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Psychrobacter sp. PRwf-1
Length = 357
Score = 77.4 bits (182), Expect = 5e-13
Identities = 89/366 (24%), Positives = 138/366 (37%), Gaps = 43/366 (11%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAY--------------CAEGEK 50
+LVTG AG++G H LL R GD +I+ VDNL++ Y + E
Sbjct: 3 ILVTGAAGFIGFHVCQKLLAR---GD--QIIGVDNLNDYYDVSLKMARLSELGVTLDAET 57
Query: 51 KPEALKRIEELTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEY 110
+ + F K+DI A++ +F H D V H AA V S+E P Y
Sbjct: 58 MTADHSSRDSTSSANFEFIKLDIADRAAMESLFAEHQFDAVCHLAAQAGVRYSIENPHVY 117
Query: 111 YQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYF 170
+ N+ G + E R+H V L ++SS +VYG + P S T + S Y +K
Sbjct: 118 VETNVVGFLNILEGCRQHNVDNLCFASSSSVYGLNQSQPFKTSDHTDHPV-SLYAATKK- 175
Query: 171 CEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKEL 230
E+M LR+F G P G P+ + P + A+ + +
Sbjct: 176 SNEMMAHTYAHLFGIRCTGLRFFTVYG----------PWGRPD-MAPMLFADAISNNRPI 224
Query: 231 KVFGDDYPTADGTGVRDY----IHVCDLAAGHVQAIKLFHQPGFNG-------FHAINLG 279
KVF + D T V D + + D AG P + N+G
Sbjct: 225 KVFNHGDMSRDFTYVGDIAEGILAILDTPAGSKDVGAPTFDPRHPSPETSSAPYRLYNIG 284
Query: 280 TGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMC 339
+ +++ + G GDV + AD + T+ G+ L +
Sbjct: 285 NNSPVNLMVFIRTLEAEFGTEAQKIMMDMQPGDVASTYADSSSLTQLTGFTPNTELAEGI 344
Query: 340 RDTWRW 345
+ W
Sbjct: 345 KHFANW 350
>UniRef50_Q0W7F9 Cluster: Putative UDP-glucose 4-epimerase; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
UDP-glucose 4-epimerase - Uncultured methanogenic
archaeon RC-I
Length = 306
Score = 77.4 bits (182), Expect = 5e-13
Identities = 68/204 (33%), Positives = 100/204 (49%), Gaps = 30/204 (14%)
Query: 88 IDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPEY 147
+D V H AA+ V S+ P+ ++ N GT + E RK GV K VY SS VYG P+Y
Sbjct: 67 VDIVYHLAAISNVDASIRNPIRTFETNAMGTANVLEEARKAGVKKFVYVSSAHVYGVPQY 126
Query: 148 LPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS-DKKWAIISLRYFNPVGAHESGRIGE 206
LPI+E HP Y SK E I++ S ++AI LR FN G G+
Sbjct: 127 LPIDEKHPVVP--REAYAASKIAAENIVQAYGNSYGIEYAI--LRPFNIFGP------GQ 176
Query: 207 DPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFH 266
DPS L+P + + A+ +KV G+ PT RD++++ D A+++
Sbjct: 177 DPS----FLIPGVIKQALEN-GVIKV-GNTEPT------RDFLYIED-------AVRVML 217
Query: 267 QPGFNGFHAINLGTGTGYSVLEMV 290
G G N+G+G +L++V
Sbjct: 218 LAGEKGTGIFNIGSGQQTKILDIV 241
>UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellular
organisms|Rep: Nucleotide sugar epimerase -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 338
Score = 77.0 bits (181), Expect = 7e-13
Identities = 54/155 (34%), Positives = 78/155 (50%), Gaps = 10/155 (6%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTG AG++G + LL R GD ++ +DNL++ Y +K I G+
Sbjct: 3 VLVTGVAGFIGHGAALALLRR---GD--RVIGLDNLNDYYDVNLKKSRLEHLNISSQPGQ 57
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ F K+D+ ++++F + + VIH AA V S+E P Y NI G + E
Sbjct: 58 FI-FRKIDLVDRLGVNQLFADFSPQKVIHLAAQAGVRYSLENPFAYIDSNIVGFLHILEA 116
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPI----NESHP 155
R H V LVY+SS +VYG + LP N HP
Sbjct: 117 CRHHRVEHLVYASSSSVYGANKKLPFSVHDNVDHP 151
>UniRef50_Q2RPP2 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Rhodospirillum rubrum ATCC 11170|Rep: NAD-dependent
epimerase/dehydratase - Rhodospirillum rubrum (strain
ATCC 11170 / NCIB 8255)
Length = 328
Score = 77.0 bits (181), Expect = 7e-13
Identities = 86/298 (28%), Positives = 136/298 (45%), Gaps = 45/298 (15%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R VLVTGGAG++G H L R+ G E+VV+D+LS ++ + + +
Sbjct: 17 RRVLVTGGAGFIGGH-----LCRRLVGLGAEVVVLDDLSTG------RRDTVPRGVRLIV 65
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
G AL R C H AA+ +V SV ++ + VN GT L
Sbjct: 66 GSVTD---------PALVRKALQGTEGC-FHLAAIASVPLSVSALVDCHAVNQTGTLRLI 115
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
E +R +G +LVY+SS V+G+P LP+ + PT SPYG K CE + V+
Sbjct: 116 EGLRDNGGGRLVYASSSAVFGDPVALPLTMASPTRP--ISPYGVDKLACEAHAR---VAG 170
Query: 183 KKWAIIS--LRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+ + S LR+FN G +S D S + + ++ G + + VFG
Sbjct: 171 GLYGLKSFGLRFFNVYGEGQS-----DDSPYSGVIALFNRKLRDG--QPITVFG------ 217
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
DG+ RD+++V D+ G + A +++ G +GTG +V+++ G
Sbjct: 218 DGSQSRDFVYVGDVIEGLLAA---WNEASVRG-PVETVGTGCPTTVMDLARTIMEVHG 271
>UniRef50_A6GMF7 Cluster: Nucleotide sugar epimerase; n=1;
Limnobacter sp. MED105|Rep: Nucleotide sugar epimerase -
Limnobacter sp. MED105
Length = 386
Score = 77.0 bits (181), Expect = 7e-13
Identities = 82/305 (26%), Positives = 131/305 (42%), Gaps = 32/305 (10%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL- 61
+ VLVTG AG++G H LLER GD +++ D+L++ Y + K E L ++E+
Sbjct: 47 QTVLVTGHAGFIGFHAAKALLER---GD--KVIGFDSLNSHY--DTRLKRERLTMLDEIA 99
Query: 62 --TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTC 119
TG H + D+ + L E + + VIH A S +KP E Q NIN
Sbjct: 100 KATGSKYHTVRADLCDSTQLHECLETYKVQRVIHLAGQTDKFLSQDKPAECVQNNINSFV 159
Query: 120 TLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC 179
+L E R ++ L Y+SS VYG P++E ++ CE I
Sbjct: 160 SLLEACRHFKIHHLTYASSHAVYGAGFQKPMSERDSANHPQRLD-AATQRACELIAHSYS 218
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNN-LMPYISQVAVGRLKELKVFGDDYP 238
LR+F+ G P G P++ L + ++ G K ++++ D
Sbjct: 219 -HQFNLPTTGLRFFSVYG----------PWGRPDSVLFAFTKRILEG--KPIQIYNDGSN 265
Query: 239 TADGTGVRDYIHVCDLAA------GHVQAIKLFHQPGFNG-FHAINLGTGTGYSVLEMVA 291
T D T V D + A+ V ++ Q N + +N+G S+ E++A
Sbjct: 266 TRDYTYVADLVEAILRASDTPAEPNPVWLVEAPDQATSNAPWRLLNVGNSLPVSIEELIA 325
Query: 292 AFSNA 296
A +A
Sbjct: 326 ALEHA 330
>UniRef50_A4VWA8 Cluster: UDP-glucose 4-epimerase; n=1;
Streptococcus suis 05ZYH33|Rep: UDP-glucose 4-epimerase
- Streptococcus suis (strain 05ZYH33)
Length = 107
Score = 77.0 bits (181), Expect = 7e-13
Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Query: 253 DLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGD 312
D A G+++A+ G + NLG+ G SVLE+V AF +G GD
Sbjct: 7 DCALGYIKALDTISTT--TGVYTYNLGSAQGTSVLELVKAFEKVNGVTVHYKLVDRRPGD 64
Query: 313 VTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGY 353
V A+ A + L W ++ DMC+DTW WQ NPNGY
Sbjct: 65 VATCYANADKAWKELNWNTVITMEDMCQDTWYWQSKNPNGY 105
>UniRef50_Q4AGU6 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Chlorobium phaeobacteroides BS1
Length = 304
Score = 76.6 bits (180), Expect = 9e-13
Identities = 93/346 (26%), Positives = 148/346 (42%), Gaps = 53/346 (15%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LV GG G++GSH V LL ++G + I D Y +KP +TG
Sbjct: 3 ILVLGGNGFIGSHLVDKLL---AEGHKVRIF--DKYEEHY-----RKP--------ITGC 44
Query: 65 TVHFYKVDIR--CAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
+ R A+AL+ +ID V H + S + P+ Q N+ T L
Sbjct: 45 DYRYGDFGNRGLLADALN------DIDIVFHLISTTLPETSNDDPVFDVQSNVVETLFLL 98
Query: 123 EIMRKHGVYKLVY-SSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
E + K+V+ SS TVYG P +P++E++PT + YG +K E K L +
Sbjct: 99 EQCVAKKIRKVVFISSGGTVYGIPTEIPVHENNPTNPECS--YGITKLVIE---KYLALF 153
Query: 182 DKKWAI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+ + + +R NP G ++ P+ I + ++++VA G + + ++GD
Sbjct: 154 KHLYGLNYVIVRPSNPYGERQN------PNSIQGAIPVFLNKVAKG--ESIDIWGD---- 201
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
G VRDYI + DL G +A + Q NLG+ TGYS+ +V +G
Sbjct: 202 --GEVVRDYIFIDDLVDGIYKAATVKAQSCI-----FNLGSSTGYSLNYIVKIIRQITGR 254
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
D+ D++ A + L W SL TW +
Sbjct: 255 QVEIKYKAKRTFDIPEIYLDISRAGKELSWAPVTSLESGIEKTWEF 300
>UniRef50_A1IA72 Cluster: Putative UDP-glucose-4-epimerase
precursor; n=1; Candidatus Desulfococcus oleovorans
Hxd3|Rep: Putative UDP-glucose-4-epimerase precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 305
Score = 76.6 bits (180), Expect = 9e-13
Identities = 65/258 (25%), Positives = 108/258 (41%), Gaps = 23/258 (8%)
Query: 89 DCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVY-SSSCTVYGEPEY 147
D VIH A+ G S +PL NI T L ++ R G +++ SS T+YG PE
Sbjct: 66 DVVIHLASATTPGSSAGRPLAEADTNILPTLKLLDMFRDCGNRWMIFVSSGGTLYGNPET 125
Query: 148 LPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGED 207
+P+NES P S +G K E + K I P + G+
Sbjct: 126 VPVNESQPL--CPLSYHGAGKIAIEAFLHAFAHDSGKHVTI----LRPANVYGPGQPLSQ 179
Query: 208 PSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQ 267
G ++ + E+K++G DG+ VRD++++ D+ G ++++ +
Sbjct: 180 GFGFIRTVLEHARMDT-----EVKIWG------DGSTVRDFLYIEDMIKG-IESV-MNAD 226
Query: 268 PGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSL 327
P + + N+G+G G+S+ ++ G DV V D +
Sbjct: 227 PHTDTY---NIGSGEGHSLNNVIKTVEKVCGRPLKVQYSTARQVDVRKIVLDCSKIMEKT 283
Query: 328 GWRATRSLHDMCRDTWRW 345
GW+ SL + R TW+W
Sbjct: 284 GWKPETSLEEGVRLTWQW 301
>UniRef50_Q8YRD9 Cluster: Nucleotide sugar epimerase; n=6;
Cyanobacteria|Rep: Nucleotide sugar epimerase - Anabaena
sp. (strain PCC 7120)
Length = 316
Score = 75.8 bits (178), Expect = 2e-12
Identities = 92/346 (26%), Positives = 148/346 (42%), Gaps = 38/346 (10%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
++VTG AG++ SH V TLL++ G+ E++ +D +++ Y + K + + ++
Sbjct: 4 IIVTGAAGFIASHLVETLLKQ---GE--EVIGIDEVNDYY--DPLLKRKNIAHLQSFPNF 56
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLE-YYQVNINGTCTLFE 123
T F + DI + LD ++ V H AA V S Y + NIN T L E
Sbjct: 57 T--FIEGDI---QFLDWPSLLQDVTVVYHQAAQAGVRASWGNGFRAYTERNINATQVLLE 111
Query: 124 IMR-KHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
+ + +LV++S+ +VYG+ E LP +E P SPYG +K E + L +
Sbjct: 112 AAKDAQQLTRLVFASTSSVYGDAETLPTHEGIP--PQPVSPYGITKLAAERLC-GLYHKN 168
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
++LRYF G + P + + Q + + V+GD T D
Sbjct: 169 FGVPFVALRYFTVYGPRQR------PDMAFHKFFKSVLQD-----EAIPVYGDGQQTRDF 217
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
T V D + +LAA V P G N+G G+ + E++ G
Sbjct: 218 TFVSDAV-AANLAAASV--------PAAVG-EIFNIGGGSRVVLAEVLDTMEQIVGQPIK 267
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEA 348
GD ADV+ A + LG+ SL + W+W +A
Sbjct: 268 RNHIEKAMGDARHTAADVSKARKILGYEPKVSLREGLSLEWQWVKA 313
>UniRef50_Q2WB63 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=2; Alphaproteobacteria|Rep:
Nucleoside-diphosphate-sugar epimerase -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 333
Score = 75.8 bits (178), Expect = 2e-12
Identities = 94/332 (28%), Positives = 139/332 (41%), Gaps = 37/332 (11%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
MS +LVTGGAG++GSH V L+ S G + V+D+ S A + A +
Sbjct: 1 MSGRILVTGGAGFIGSHLVDLLV---SQGQA--VTVLDDFSTGEAANLAEAGGA-GDVRV 54
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
LTG T+ E DR+F A++ V +S+ +P+E + VN GT
Sbjct: 55 LTG-TILDRDAVAAAMEGCDRVFH----------LAVQCVRKSLGQPIENHDVNATGTLY 103
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
L E RK V + VY SS VYG +NE + +T YG +K E+
Sbjct: 104 LLEEARKRQVSRFVYCSSSEVYGNGRDSLLNEDRTVCEPVT-VYGAAK-LAGELYAKAYH 161
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+ +R FN G E + G+ IP L+ ++ + +FG
Sbjct: 162 RTYGLPTVVVRPFNSYGPREHYK-GQRAEVIPRFLIRVLNGLPP------TIFG------ 208
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSN-ASGX 299
DG+ RD+ +V + A G A + G IN+ G +V E+ + +
Sbjct: 209 DGSAGRDFTYVTETARGLAMAAQCDALVG----REINIAYGRMVTVKEVAESITRLCQRP 264
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRA 331
GDV A AD ALA LG++A
Sbjct: 265 DIAPSYGPGRPGDVKALHADTALARSLLGFKA 296
>UniRef50_A7HIS5 Cluster: dTDP-glucose 4,6-dehydratase; n=5;
cellular organisms|Rep: dTDP-glucose 4,6-dehydratase -
Anaeromyxobacter sp. Fw109-5
Length = 336
Score = 75.8 bits (178), Expect = 2e-12
Identities = 100/357 (28%), Positives = 143/357 (40%), Gaps = 44/357 (12%)
Query: 5 VLVTGGAGYVGSHTV-ITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
VLVTGG+G++G++ V + L+ER +V +D L+ A AE + EL G
Sbjct: 3 VLVTGGSGFIGANLVRLLLVERPG----WRVVNLDALTYAGNAEN---------LAELDG 49
Query: 64 KTVH-FYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
+ F + DI E + + E ID V+H AA V S+ P + + N+ GT L
Sbjct: 50 HARYRFVRGDICNGELVADVLETERIDAVLHLAAESHVDRSILSPPVFIETNVRGTQVLL 109
Query: 123 EIMRKHGVYKLVYSSSCTVYGE--PEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
E R+ GV + V+ S+ VYG P L E P S SPY SK +++
Sbjct: 110 EAARELGVRRFVHVSTDEVYGSLGPSGL-FTEETPLDPS--SPYSASK-ASSDLLALAYA 165
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+ ++ R N G P P L+P A+ L L V+G
Sbjct: 166 RTFELPVVVTRCSNNYG----------PYQFPEKLIPLAIANALRDL-PLPVYG------ 208
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX- 299
DG VRD+IHV D G + A+ + G +G NLG + L++V G
Sbjct: 209 DGLHVRDWIHVEDHCRGLLAAL----EKGESG-QVYNLGASSERHNLDVVKQVLRLVGKP 263
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANPNGYHRI 356
G D A LGW + T RW + RI
Sbjct: 264 ESLIQHVADRPGHDRRYAIDSTKARTVLGWAPRHRFEEALAATVRWYVERRPWWERI 320
>UniRef50_UPI00015BAE89 Cluster: NAD-dependent
epimerase/dehydratase; n=1; Ignicoccus hospitalis
KIN4/I|Rep: NAD-dependent epimerase/dehydratase -
Ignicoccus hospitalis KIN4/I
Length = 293
Score = 75.4 bits (177), Expect = 2e-12
Identities = 71/279 (25%), Positives = 121/279 (43%), Gaps = 34/279 (12%)
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
V F +V++ + L E + + V H AA ES+ +P + +VN+ GT + E
Sbjct: 38 VKFTRVNVLLLDDLK--VELRDCELVYHLAAEIKAEESLREPAKVVRVNVEGTLNVLEAA 95
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDL--CVSDK 183
R +V++S+ VYGE + +P+ E HP + YG +K E ++ +
Sbjct: 96 RLADA-SVVFASTAAVYGEAKVVPVPEEHPL--EPVNVYGATKVAGEALVNSYRKAFGLR 152
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
W + + P + G +GE ++ + G + L+++G DG
Sbjct: 153 AWTLRLFNVYGPSASPSRGVVGE-----------FLRRALKG--EPLRIYG------DGR 193
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
VRD++ V D+ V+A KL + + N+G+G G S++ + +G
Sbjct: 194 QVRDFVFVDDV----VKAFKLVREIPEGTY---NVGSGRGVSIITLAKKIIELTGSKSEM 246
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDT 342
GDV +VADV + GWR SL + R T
Sbjct: 247 VFLPERPGDVRVSVADVT-KLAAFGWRPRVSLEEGLRLT 284
>UniRef50_Q5L1Q6 Cluster: NDP-sugar epimerase; n=6; Bacillaceae|Rep:
NDP-sugar epimerase - Geobacillus kaustophilus
Length = 318
Score = 75.4 bits (177), Expect = 2e-12
Identities = 88/333 (26%), Positives = 145/333 (43%), Gaps = 39/333 (11%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEEL-TG 63
+LVTG AG++GSH L E+ + D ++ VD A P K I L +
Sbjct: 3 ILVTGAAGFIGSH----LCEKLLENDEHHVIGVDGFLGPTPA-----PLKAKNIAHLQSH 53
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQV-NINGTCTLF 122
F ++D+ A+ L + + N++ V H A + V S Y NI+ T L
Sbjct: 54 PRFTFLELDLLTAD-LPSLLQ--NVEAVYHLAGMPGVRTSWGTEFAAYAAHNISTTQRLL 110
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
E + + + +Y+S+ +VYGE P++E+ + SPYG +K E + + + +
Sbjct: 111 EACKDRPLKRFIYASTSSVYGERSG-PLSET--LEPAPLSPYGITKLTGEHLCR-VYFRE 166
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
I+ LRYF G + + + +I Q+ G + L VFG DG
Sbjct: 167 FAVPIVILRYFTVYGPRQRPDM---------SFHRFIRQLLAG--QPLTVFG------DG 209
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
T RD+ ++ D G + A++ + G G IN+G SV E++ +G
Sbjct: 210 TQSRDFTYISDCVDGTIAALE---RDGVIG-ETINIGGKERASVNEVIRLLETLTGKQAI 265
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSL 335
G+ AD+A A R LG++ +L
Sbjct: 266 IQYTPSARGEPKQTWADLAKAERLLGYKPVVTL 298
>UniRef50_Q07KU6 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=2; Alphaproteobacteria|Rep: NAD-dependent
epimerase/dehydratase precursor - Rhodopseudomonas
palustris (strain BisA53)
Length = 317
Score = 74.9 bits (176), Expect = 3e-12
Identities = 101/345 (29%), Positives = 142/345 (41%), Gaps = 49/345 (14%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNL---SNAYCAEGEKKPEALKRIEEL 61
+LVTGG GYVG L D ++VVD L +N +C + L R++ +
Sbjct: 3 ILVTGGNGYVGRELCRQLY------DSHRVLVVDELRYGANRFCEDD------LARLDLI 50
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
D+R A+ R F D VIH AA+ + E P N+ GT +
Sbjct: 51 QADVS-----DVRAMAAV-REFAP---DVVIHLAAIHYIPECETNPALAVSTNVAGTVAM 101
Query: 122 FEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
+ + V++SS VY P+ P +E+ T YG SK E ++ + +
Sbjct: 102 LQACPPG--CRFVFASSGAVYA-PDASPHSETEAATVP-TDIYGLSKLQGEHYVRYIARA 157
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
A+I +R FN VG E+ P+ L I+Q+ G + +++ G+ +P
Sbjct: 158 RGFPAVI-VRLFNVVGPGETN---------PHLLPEIIAQLKAGN-RSIRL-GNLWPK-- 203
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
RDYIHV D A G A L A+NLGT YSV E+V SG
Sbjct: 204 ----RDYIHVRDAARGFAAAA-LEGAVANGDAVAVNLGTSKAYSVSEVVERLRRISGCQF 258
Query: 302 XXXXXXXXXGDVTANV--ADVALATRSLGWRATRSLHDMCRDTWR 344
V V ADV R GW A S+ D D WR
Sbjct: 259 ELLEDSSRVRAVDRPVLAADVGRIRRMFGWSARLSIDDALSDLWR 303
>UniRef50_Q9RZB3 Cluster: Thymidine diphosphoglucose
4,6-dehydratase; n=9; cellular organisms|Rep: Thymidine
diphosphoglucose 4,6-dehydratase - Deinococcus
radiodurans
Length = 364
Score = 73.7 bits (173), Expect = 7e-12
Identities = 90/348 (25%), Positives = 149/348 (42%), Gaps = 38/348 (10%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+++LVTGG G++GS+ V L + + ++VV D L+ A G K E L + +
Sbjct: 14 KSLLVTGGCGFIGSNFVRYWLGQHPES---KVVVYDKLTYA----GRK--ENLHDLWD-- 62
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
+ DI + + R + +++D +++FAA V +S+ PL + + N+ GT L
Sbjct: 63 NPALSLVVGDIGDMDLVRRTCQENDVDLIVNFAAETHVDQSILGPLVFTETNVRGTHVLL 122
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGK-SLTSPYGKSKYFCEEIMKDLCVS 181
E+ R+ G+ +L + S+ VYG + ++S T + + SPY SK +++++ ++
Sbjct: 123 EVARELGI-RLHHISTDEVYGHIK--DGHQSVETDELAPRSPYAASKAAADQLVQAYAIT 179
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
Y PV G P P +P S A+ + L V+G D
Sbjct: 180 ----------YGIPV-TITRGANNVGPYQYPEKAVPLFSTNAI-LGEPLPVYG------D 221
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
G +RDY HV D G ++ + L G N+GTG + LEMV G
Sbjct: 222 GQQMRDYAHVYDHCTG-IETVLLRGNIG----EVYNVGTGREMTNLEMVDIVLETLGKDH 276
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
+ RSLGW+ + RW E N
Sbjct: 277 SLVKHVTDRPGHDRRYSMNVDKLRSLGWQPKYDPKQAVAEAARWYEGN 324
>UniRef50_A5C3L4 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 619
Score = 73.7 bits (173), Expect = 7e-12
Identities = 79/290 (27%), Positives = 130/290 (44%), Gaps = 38/290 (13%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R +L+TG AG++ SH L++ D IV +D L YC+ + + +
Sbjct: 11 RNILITGAAGFIASHVTNRLVKNHPD---YRIVALDKLD--YCSNVKNLGPSR------S 59
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
F K DI CA+ ++ + +ID ++HFAA V S E+ NI GT L
Sbjct: 60 SSNFKFVKGDIVCADLVNHLLVAEDIDTIMHFAAQTHVDNSFGNSFEFTNNNIYGTHVLL 119
Query: 123 EIMR-KHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSL--TSPYGKSKYFCEEIMKDLC 179
E + + + ++ S+ VYGE + L + +P L T+PY +K E ++
Sbjct: 120 EACKVTKRIKRFIHVSTDEVYGETD-LDTDIGNPEASQLLPTNPYSATKAGAEMLVMAYH 178
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
S I+ R N G P+ P L+P +A+ + ++L + G
Sbjct: 179 RS-YGLPTITTRGNNVYG----------PNQFPEKLIPKFILLAM-KGEQLPIHG----- 221
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEM 289
DG+ VR Y++ D+A +A ++ G G H N+GT SVL++
Sbjct: 222 -DGSNVRSYLYCEDVA----EAFEVVLHKGVIG-HVYNIGTKKERSVLDV 265
>UniRef50_Q7V972 Cluster: Possible UDP-glucose-4-epimerase; n=1;
Prochlorococcus marinus str. MIT 9313|Rep: Possible
UDP-glucose-4-epimerase - Prochlorococcus marinus
(strain MIT 9313)
Length = 308
Score = 73.3 bits (172), Expect = 9e-12
Identities = 89/328 (27%), Positives = 143/328 (43%), Gaps = 47/328 (14%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
+V G +G++GSH V LL + S V LS G P+A ++ G
Sbjct: 4 VVVGASGFIGSHLVDALLAQGSQ--------VRALSRHL--PGLITPKA----QDHPGLV 49
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+H +D+ L++ I + H A+ S P E +N+ G L E
Sbjct: 50 LH--PLDMADRLGLEKALVGSEI--IFHLASGSLPQSSNRNPREDININVLGALNLLEAS 105
Query: 126 RKHGVYKLVY-SSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
+ G+ K V+ SS TVYG P+ +PI E+HPT + YG +K E K + +
Sbjct: 106 LEVGIQKFVFVSSGGTVYGIPKQVPIAENHPTDPICS--YGITKLAIE---KYVSLYRHL 160
Query: 185 WAIIS--LRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
+ + S +R NP G E R+ +P ++++ R + L+++GD G
Sbjct: 161 YGLNSTVVRLANPYG--ERQRLDSCQGVVP----VFLNRAL--RSEPLEIWGD------G 206
Query: 243 TGVRDYIHVCDLAAGHVQAI-KLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
+ +RD++++ D+ VQA+ + H G N+G+G G S+ E+V N G
Sbjct: 207 STIRDFLYITDV----VQALLAISHYKGPENL--FNVGSGIGLSLCELVKLIENELGRPL 260
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGW 329
DV NV + A LGW
Sbjct: 261 QVSYQQSRTFDVPTNVLSIKRARNCLGW 288
>UniRef50_A3H793 Cluster: NAD-dependent epimerase/dehydratase; n=3;
Archaea|Rep: NAD-dependent epimerase/dehydratase -
Caldivirga maquilingensis IC-167
Length = 325
Score = 73.3 bits (172), Expect = 9e-12
Identities = 100/354 (28%), Positives = 147/354 (41%), Gaps = 49/354 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
V+VTGGAG++GSH V L+ D E+ V+DN S+ + LK E L+
Sbjct: 10 VIVTGGAGFIGSHLVDRLVR-----DGYEVTVLDNFSSGDVSN-------LK--ESLSTG 55
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V+ K D++ D + E V H AA V S +P ++ N+ T + E
Sbjct: 56 RVNVVKADLKYWG--DWVSEFKGAYAVFHLAANPEVRVSSVEPRSHFDNNLVATFNVAEA 113
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
R V +V++SS TVYG+ + LP E HP S YG +K EI+ D
Sbjct: 114 ARVSDVKYIVFASSSTVYGDAKVLPTPEDHPI--IPISVYGATK-AAGEIILDTYSRLYG 170
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+++LRY N VG + D YI R EL+V G DG+
Sbjct: 171 IRVVNLRYANIVGPRSRHGVIYD---------FYIKLTRNPR--ELEVLG------DGSQ 213
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQ--PGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
+ Y++V D ++ LF++ G A N+G +V+++ G
Sbjct: 214 RKSYLYVDDAVDA---SLFLFNKLINGSLQEQAFNVGNKDWVTVMDIARIVIEELGLRNV 270
Query: 303 XXXXXXXX-------GDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
GDV + DV ++ LGW S D R T RW + N
Sbjct: 271 NIVTRAMTPDGRGWLGDVKYMLLDVDKLSK-LGWSPRYSSADAVRLTIRWLKGN 323
>UniRef50_Q8ZW82 Cluster: UDP-glucose 4-epimerase; n=6;
Thermoprotei|Rep: UDP-glucose 4-epimerase - Pyrobaculum
aerophilum
Length = 314
Score = 72.9 bits (171), Expect = 1e-11
Identities = 94/345 (27%), Positives = 146/345 (42%), Gaps = 52/345 (15%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
++VTGGAG++GSH V L+E +G E+VVVDNLS+ G + E K
Sbjct: 3 IVVTGGAGFIGSHLVDRLVE---EGH--EVVVVDNLSS-----GRR---------EFVNK 43
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
Y D++ ++ I D V HFAA V S +P+ ++ N+ T + E
Sbjct: 44 AAELYIRDLKESDWGVGI----RGDVVFHFAANPEVRLSTTEPVVHFNENVLATFNVLEW 99
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
R+ GV ++++SS TVYG+ E +P E P K + S YG +K E+M
Sbjct: 100 ARQTGVKSVIFASSSTVYGDAEVIPTPEEAPY-KPI-SVYGAAK-AAGEVMCATYARLYG 156
Query: 185 WAIISLRYFNPVGAH-ESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
+++RY N +G G I + + N P + L+V G DGT
Sbjct: 157 VKCLAIRYANIIGPRLRHGVIYDFIMKLKRN--PNV----------LEVLG------DGT 198
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
+ Y+++ D + A K F + F A+N+G VL++ + G
Sbjct: 199 QRKSYLYIKDAIDATILAWKKFEEIK-EPFLALNVGNLDAIKVLDIAQIVAEVLGLRPEI 257
Query: 304 XXXXXX------XGDVTANVADVALATRSLGWRATRSLHDMCRDT 342
GDV + + GWR T + + R T
Sbjct: 258 KLVPTTPDGRGWPGDVKYMTLSITKLMKMTGWRPTMTSGEAVRKT 302
>UniRef50_Q9SYM5 Cluster: Probable rhamnose biosynthetic enzyme 1;
n=30; root|Rep: Probable rhamnose biosynthetic enzyme 1
- Arabidopsis thaliana (Mouse-ear cress)
Length = 669
Score = 72.9 bits (171), Expect = 1e-11
Identities = 90/352 (25%), Positives = 145/352 (41%), Gaps = 43/352 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT-G 63
+L+TG AG++ SH L+ D +IVV+D L YC+ LK +
Sbjct: 9 ILITGAAGFIASHVANRLIRSYPD---YKIVVLDKLD--YCSN-------LKNLNPSKHS 56
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
F K DI A+ ++ + ID ++HFAA V S E+ + NI GT L E
Sbjct: 57 PNFKFVKGDIASADLVNHLLITEGIDTIMHFAAQTHVDNSFGNSFEFTKNNIYGTHVLLE 116
Query: 124 IMRKHG-VYKLVYSSSCTVYGEPEYLPINESHPTGKSL-TSPYGKSKYFCEEIMKDLCVS 181
+ G + + ++ S+ VYGE + + +H + L T+PY +K E ++ S
Sbjct: 117 ACKVTGQIRRFIHVSTDEVYGETDEDALVGNHEASQLLPTNPYSATKAGAEMLVMAYGRS 176
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
+I+ R N G P+ P L+P +A+ R + L + G D
Sbjct: 177 -YGLPVITTRGNNVYG----------PNQFPEKLIPKFILLAM-RGQVLPIHG------D 218
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEM---VAAFSNASG 298
G+ VR Y++ D+A +A ++ G G H N+GT V ++ + N
Sbjct: 219 GSNVRSYLYCEDVA----EAFEVVLHKGEVG-HVYNIGTKKERRVNDVAKDICKLFNMDP 273
Query: 299 XXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEANP 350
D + D L + LGW + + + T W NP
Sbjct: 274 EANIKFVDNRPFNDQRYFLDDQKL--KKLGWSERTTWEEGLKKTMDWYTQNP 323
>UniRef50_Q5FRS4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=1;
Gluconobacter oxydans|Rep: UDP-N-acetylglucosamine
4-epimerase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 322
Score = 72.5 bits (170), Expect = 2e-11
Identities = 87/343 (25%), Positives = 140/343 (40%), Gaps = 32/343 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTG AG++G H LL++ +E+V VD L NAY + K L+++E G
Sbjct: 3 VLVTGVAGFIGFHVARALLKQ-----GMEVVGVDTL-NAY-YDPALKAARLEQLEPYPG- 54
Query: 65 TVHFYKVDIRCAEALDRIFENH-NIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
F KVD+ A+ + H +++ VIH AA V S+ P Y N+ G L E
Sbjct: 55 -FSFLKVDVASPAAMQDLVARHSDLEGVIHLAAQAGVRHSMVDPYSYVTSNVMGQVALLE 113
Query: 124 IMRK-HGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
R + +VY+SS +VYG + +P E+ + +S Y +K E+M +
Sbjct: 114 ACRHLKKLTHVVYASSSSVYGRNQSVPFRETDRVERP-SSVYAVTKR-AAELMSESYAYL 171
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
LR+F G P G P ++ Y A+ + + ++ + +
Sbjct: 172 HGIPQTGLRFFTVYG----------PWGRP-DMAYYGFAKAISEGRPVTLYEGKHLS--- 217
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
RD+ ++ D+ G VQ + L P +NLG V M+ G
Sbjct: 218 ---RDFTYIDDIVRG-VQQV-LGRPPEAGMSRVLNLGGDKPERVTRMIELLEQNLGKKAF 272
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
D+ + A + GW+ S D ++ W
Sbjct: 273 VERRPRPVADMESTWASLENVREFCGWKPAVSFEDGMKEFCLW 315
>UniRef50_Q2RMP3 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Rhodospirillum rubrum ATCC 11170|Rep: NAD-dependent
epimerase/dehydratase - Rhodospirillum rubrum (strain
ATCC 11170 / NCIB 8255)
Length = 319
Score = 72.5 bits (170), Expect = 2e-11
Identities = 63/244 (25%), Positives = 105/244 (43%), Gaps = 20/244 (8%)
Query: 89 DC-VIHFAALKAVGESV-EKPLEYYQVNINGTCTLFEIMRKHGVYKLVYSSSC-TVYGEP 145
DC VIH A + ++ + P+ N+ T L +++R G +L+++SS TVYG
Sbjct: 63 DCDVIHHYAWSTIPQTANDDPIRDLDDNVRTTLGLLDVLRHQGKKRLIFASSGGTVYGRL 122
Query: 146 EYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIG 205
+ +P E H + YG SK C E+ + R NP GA + R
Sbjct: 123 KRIPAEEHHSLAP--ITAYGASKA-CVELYLGFYRAHHGMDCRVARISNPFGAGQDARRK 179
Query: 206 EDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLF 265
+ + ++ + G +E+ ++GD G+ +RDYIH+ DL G + A+
Sbjct: 180 QQGAA-----SAFLFKALAG--EEITIWGD------GSVIRDYIHIADLTRGLI-ALSDA 225
Query: 266 HQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATR 325
+ NLG+G G S+ E+V N G D+ A++ D+ +
Sbjct: 226 SLADHHDLPIYNLGSGVGISLNEIVETLRNRLGLTATVNYLPSRNFDIPASILDIRKSKD 285
Query: 326 SLGW 329
L W
Sbjct: 286 LLEW 289
>UniRef50_Q3ESA4 Cluster: DTDP-glucose 4,6-dehydratase; n=3;
Firmicutes|Rep: DTDP-glucose 4,6-dehydratase - Bacillus
thuringiensis serovar israelensis ATCC 35646
Length = 320
Score = 72.5 bits (170), Expect = 2e-11
Identities = 89/343 (25%), Positives = 146/343 (42%), Gaps = 39/343 (11%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++G V LL+ D E+ ++DNL+N+ A + L + + G
Sbjct: 3 ILVTGGAGFIGRWVVKRLLQ-----DKHEVWILDNLANSTTANITEFAHDLNLKQCIQG- 56
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
DI+ + + ++FEN++ D H AA V +S++ ++ + GT L E
Sbjct: 57 -------DIKDKKLVAQLFENNSFDLCYHLAASINVQDSIDDARATFENDTIGTFNLLEQ 109
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLP-INESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+ V K+V+ S+C VY + + I+E P + SPY SK E ++ +
Sbjct: 110 CLNYDV-KMVFMSTCMVYDKATNIQGISELDPIKPA--SPYAGSKIAAENMVLSYYYA-Y 165
Query: 184 KWAIISLRYFNPVGA-HESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
K ++ +R FN G ++G G + NN + + L ++G DG
Sbjct: 166 KLPVVVIRPFNTYGPFQKTGGEGGVVAIFINNKLDNV---------PLNIYG------DG 210
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
RD ++V D A V A + NG H IN GTG S+ +A + +
Sbjct: 211 KQTRDLLYVEDCADFVVAA---GYSAKANG-HIINAGTGQDISI-NKLAELISGNKVSIQ 265
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
++ + + A L W SL D T W
Sbjct: 266 HVTHIHPQSEIQKLLCNYEKAKTILNWEPKVSLEDGVIKTEEW 308
>UniRef50_Q20YR4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Rhodopseudomonas palustris BisB18|Rep: NAD-dependent
epimerase/dehydratase - Rhodopseudomonas palustris
(strain BisB18)
Length = 345
Score = 72.5 bits (170), Expect = 2e-11
Identities = 89/329 (27%), Positives = 140/329 (42%), Gaps = 45/329 (13%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
+V GG+G++G H V L+ER GD + +V + + Y A+ KP A
Sbjct: 31 VVIGGSGFLGRHVVRALIER---GDAVTVVDI----SPYPAD---KPHAAPPCR------ 74
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+D+ A D V H+A + P VN+ T + E +
Sbjct: 75 ----LIDLSTARPGDFDAIVGTATTVHHYAWTTVPQTANADPATDLHVNLGVTLQILEAI 130
Query: 126 RKHGVYKLVY-SSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCE---EIMKDLCVS 181
++ G +V+ SS TVYG + +P+ E+H + YG SK E + +DL
Sbjct: 131 KRRGGGIVVFPSSGGTVYGRLQCVPVPETHALAP--ITAYGASKAAAELYFNVYRDLHGI 188
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
D + A I+ NP G ++ R P G+ + + + G E ++GD
Sbjct: 189 DARIARIA----NPFGPGQNPR---RPQGVASTIT---YRALAGEAVE--IWGD------ 230
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
G+ VRD+IH+ D +G + A+ + N+G+G G SV E+VA G
Sbjct: 231 GSVVRDFIHISDAVSG-LLAVADAKPTSPHILPTYNIGSGKGASVREIVAMVERHLGRPI 289
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWR 330
DV +V D++ AT LGWR
Sbjct: 290 AIEKKPERAFDVPTSVLDISRATTELGWR 318
>UniRef50_A1CX38 Cluster: Dtdp-glucose 4,6-dehydratase; n=6;
Pezizomycotina|Rep: Dtdp-glucose 4,6-dehydratase -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 411
Score = 72.1 bits (169), Expect = 2e-11
Identities = 77/256 (30%), Positives = 115/256 (44%), Gaps = 34/256 (13%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R ++VTGGAG++GS L+ + IVV D L YC+ ++ +E +
Sbjct: 41 RNIMVTGGAGFIGSWVARHLVLTYPES--YYIVVFDKLD--YCSSINN----IRMLEAMP 92
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
F D+ A+ + R H ID VIHFAA V S + + NI GT L
Sbjct: 93 N--FKFVHGDVTSADDVMRCLHAHKIDVVIHFAAQSHVDLSFRNSYSFIRDNIYGTNVLL 150
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSL--TSPYGKSKYFCEEIMKDLCV 180
E +R+ G+ + ++ S+ VYGE E P L T+PY SK E ++
Sbjct: 151 ESVRQSGIRRFIHVSTDEVYGEVP--DDGEDLPEDSILAPTNPYSASKAAAEMMILAYSK 208
Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDDYPT 239
S + AI+ +R N G H+ P ++P +IS + G ++L V+G
Sbjct: 209 SFRLPAIV-VRLNNVYGPHQ----------FPEKVIPKFISLLQRG--QKLTVYG----- 250
Query: 240 ADGTGVRDYIHVCDLA 255
DGT R Y+ D A
Sbjct: 251 -DGTNSRRYLWAGDAA 265
>UniRef50_Q7UWT1 Cluster: Udp-glucose 4-epimerase; n=3;
Bacteria|Rep: Udp-glucose 4-epimerase - Rhodopirellula
baltica
Length = 334
Score = 71.7 bits (168), Expect = 3e-11
Identities = 49/150 (32%), Positives = 73/150 (48%), Gaps = 15/150 (10%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R +L+TGGAG VG L + + E+VVVDNL + K P A +
Sbjct: 18 RKILITGGAGNVGGSLACRLAQSPDN----EVVVVDNLVTG---DRSKLPPA-------S 63
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
+ V F K D+ + L I D V H+AAL V ++ P+ + +ING +
Sbjct: 64 AENVRFIKADVNRMDDLSPIMTATRFDAVFHYAALVGVQRTLANPVAVLE-DINGIRNVL 122
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINE 152
+ + GV ++ Y+SS VYGEP +P +E
Sbjct: 123 SLSKNTGVGRVFYASSSEVYGEPVEMPQHE 152
>UniRef50_Q319Q1 Cluster: UDP-glucose 4-epimerase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: UDP-glucose
4-epimerase - Prochlorococcus marinus (strain MIT 9312)
Length = 317
Score = 71.7 bits (168), Expect = 3e-11
Identities = 57/170 (33%), Positives = 89/170 (52%), Gaps = 23/170 (13%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M + L+TGGAG++GS+ + LLE + + V DNLS G K LK
Sbjct: 1 MKKNFLITGGAGFIGSNLINKLLEIPENN----VFVFDNLST-----GRKTN--LK---- 45
Query: 61 LTGKTVHFYKVDIRCA-EALDRIFENHNIDCVIHFAALKAV-GESVEKPLEYYQVNINGT 118
L K ++FY +D++ ++ E ID + HFAA V G + + +++Y+ N+ T
Sbjct: 46 LDNKNLNFYNIDLKTPYRDWPQLKE---IDTLFHFAANADVRGGEINRDIDFYE-NVIVT 101
Query: 119 CTLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSK 168
+ + K+ + K+ +SSS TVYGEP P E++ + TS YG SK
Sbjct: 102 KAICDYASKNKIKKVAFSSSATVYGEPNIFPTPENY--SSTQTSVYGASK 149
>UniRef50_A4BEM6 Cluster: Probable nucleotide sugar dehydratase;
n=1; Reinekea sp. MED297|Rep: Probable nucleotide sugar
dehydratase - Reinekea sp. MED297
Length = 321
Score = 71.7 bits (168), Expect = 3e-11
Identities = 58/184 (31%), Positives = 88/184 (47%), Gaps = 17/184 (9%)
Query: 70 KVDIRCAEALDRIF---ENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMR 126
+V++ C + D F +ID V H AAL A+ S P Y N+ GT + +
Sbjct: 46 QVEVVCGDVRDPYFCQTLTKDIDWVFHLAALIAIPYSYTAPDSYVDTNVKGTLNICQAAL 105
Query: 127 KHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWA 186
+GV +++++S+ VYG +Y+PI+E HP SPY SK + + +
Sbjct: 106 HNGVEQVIHTSTSEVYGTAQYVPIDEQHPLQPQ--SPYSASKMSGDHMALSF-FNAFGLP 162
Query: 187 IISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVR 246
+ R FN G +S R + IP+ I+Q+A G+ K LK+ GD PT D V
Sbjct: 163 VSVARPFNTYGPRQSAR-----AVIPS----VITQIASGK-KVLKL-GDLSPTRDFNYVT 211
Query: 247 DYIH 250
D H
Sbjct: 212 DTCH 215
>UniRef50_Q97H47 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=6; Clostridium|Rep: Nucleoside-diphosphate-sugar
epimerase - Clostridium acetobutylicum
Length = 332
Score = 71.3 bits (167), Expect = 3e-11
Identities = 69/214 (32%), Positives = 102/214 (47%), Gaps = 40/214 (18%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++G V LL+ DG+ + +DNLSN +++ IEE G+
Sbjct: 3 ILVTGGAGFIGRWVVKKLLD---DGNT--VTALDNLSNG----------SIENIEEFKGE 47
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F + DI+ + LDRIFE+ D + H AA V ES++ P + + + GT + E
Sbjct: 48 NFKFIEGDIKNKDDLDRIFED-KYDIIYHLAASIVVQESIDDPEKTFFNDTVGTFNILER 106
Query: 125 MRK-----HG--------------VY--KLVYSSSCTVYGEPEYLPINESHPTGKSLTSP 163
+K HG VY K+V+ S+C VY I+E H SP
Sbjct: 107 AKKQMFGQHGKMNGSIWNIDENDEVYPCKVVFMSTCMVYDISGETGIDEQHSV--KPVSP 164
Query: 164 YGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVG 197
YG SK E ++ + K A++ +R FN G
Sbjct: 165 YGGSKIAAENMVLSYFNAYKLPAVV-IRPFNTYG 197
>UniRef50_Q58M85 Cluster: Nucleotide-sugar epimerase; n=1;
Cyanophage P-SSM2|Rep: Nucleotide-sugar epimerase -
Cyanophage P-SSM2
Length = 301
Score = 71.3 bits (167), Expect = 3e-11
Identities = 79/290 (27%), Positives = 130/290 (44%), Gaps = 39/290 (13%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTG AG++GS+ LL+ +++ VDN S A+ +K K
Sbjct: 7 LVTGAAGFIGSNLTDYLLDLDH-----QVICVDNKS----ADNDKF--------HWNDKA 49
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+ DI +A+ +F + +D V H AA + +++ P++ Q N GT T+ +
Sbjct: 50 WNV-DCDITDYKAMKNVF--NKVDYVFHLAAESRIQSAIDNPIQAVQRNCVGTATVLQCA 106
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
R+ GV + VYSS+ + YG + P E+ P +PY +K E++ K + +
Sbjct: 107 REAGVKRFVYSSTSSGYGNNPF-PNVETQP--DDCLNPYSATKVAGEKLCK-MYTNLYGL 162
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
+ LRYFN G S G+ Y + + R ++L DG+
Sbjct: 163 ETVVLRYFNVFG-QRSPTKGQ-----------YAPVIGIFR-RQLDSKEPLTIVGDGSQR 209
Query: 246 RDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSN 295
RD++HV D+A + A + G G N+G+G YSV E+ S+
Sbjct: 210 RDFVHVNDVARANYLA-SILPLQGHEG-EVFNVGSGKNYSVQEIADVISD 257
>UniRef50_Q4CYB9 Cluster: GDP-mannose 4,6 dehydratase, putative;
n=3; root|Rep: GDP-mannose 4,6 dehydratase, putative -
Trypanosoma cruzi
Length = 378
Score = 71.3 bits (167), Expect = 3e-11
Identities = 83/289 (28%), Positives = 132/289 (45%), Gaps = 41/289 (14%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R +LVTGG G++GS+ + LL S + VD YC+ + + IE +
Sbjct: 22 RHLLVTGGLGFIGSNFINHLLRTHSGVHVYNLDKVD-----YCS-------SFRSIENPS 69
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
HF + +I A+ + + +H+ID +I+FAA V S L + N+ GT L
Sbjct: 70 DPYYHFVRGNITNADLVMYVLRHHDIDTIINFAAQSHVDNSFGNSLSFTYNNVLGTHVLL 129
Query: 123 EIMRKHG-VYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
E R +G + K ++ S+ VYG+ + ++ + T+PY +K E I+K +S
Sbjct: 130 ECARTYGRIEKFIHVSTDEVYGQ---VTDSKKEEGTLNPTNPYAATKAAVEYIVKSYHIS 186
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDDYPTA 240
II+ R N G P P L+P +I + G K+L + G
Sbjct: 187 FGLPCIIT-RGNNVYG----------PYQYPEKLIPRFIMLMNAG--KKLTIQG------ 227
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEM 289
+G+ R +IH D+A V I H GF G N+G+ SVL++
Sbjct: 228 NGSNKRTFIHASDVARAFVAIIN--H--GFIG-DVYNIGSCDEKSVLDI 271
>UniRef50_Q0F315 Cluster: DTDP-D-glucose 4,6-dehydratase; n=3;
Proteobacteria|Rep: DTDP-D-glucose 4,6-dehydratase -
Mariprofundus ferrooxydans PV-1
Length = 367
Score = 70.9 bits (166), Expect = 5e-11
Identities = 71/269 (26%), Positives = 122/269 (45%), Gaps = 28/269 (10%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++G + V +L SD D + ++ +D L+ A + ++EL +
Sbjct: 9 MLVTGGAGFIGCNFVRYMLA--SDAD-VRVINLDKLTYAGSTDN---------LKELPDQ 56
Query: 65 TVH-FYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
+ H F + DI +DR+ H+ID ++HFAA V S+ P + Q N+ GT TL E
Sbjct: 57 SRHIFVEGDICDRPLIDRLLREHHIDTIVHFAAESHVDNSIAGPEVFVQTNVMGTFTLLE 116
Query: 124 IMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
R++ + + T G P+ + ++S T + + +E+ L D
Sbjct: 117 AARQYWMGGASDAGCETTDGRPDAVTSHQSPVTSHDAPASFRFHHISTDEVYGTLSQGDP 176
Query: 184 KWAIISLRYFN-PVGAHESG-----RIGEDPSGIP-------NNLMPYI-SQVAVGRLKE 229
++ + N P A ++G R G+P NN PY + + +
Sbjct: 177 AFSEATAYAPNSPYSASKAGSDHLVRAWFHTYGLPVTTTNCSNNYGPYQHGEKFIPTVIR 236
Query: 230 LKVFGDDYPT-ADGTGVRDYIHVCDLAAG 257
+ G P DG+ +RD+++V D AG
Sbjct: 237 SCLEGKPIPVYGDGSNIRDWLYVEDHCAG 265
>UniRef50_Q7UTP9 Cluster: UDP-glucose 4-epimerase homolog; n=2;
Planctomycetaceae|Rep: UDP-glucose 4-epimerase homolog -
Rhodopirellula baltica
Length = 371
Score = 70.5 bits (165), Expect = 6e-11
Identities = 87/340 (25%), Positives = 141/340 (41%), Gaps = 39/340 (11%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTG AG++GS V LL+ + E+V +DNLS + E +R + LT
Sbjct: 57 LVTGAAGFIGSQMVERLLDAGA-----EVVALDNLSTGFKHNLTPFLEGPQR-DRLT--- 107
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
F + D + R E +D + HFAA+ +V S+ +P + T L
Sbjct: 108 --FVEGDAADRACVQRSVEG--VDHIFHFAAMASVPRSMREPGMCHDWTTTSTVELLAAG 163
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
GV + V SS+ VYG Y+ E SPY +K E + V +++
Sbjct: 164 SAAGVKRFVLSSTSAVYGNSPYVAKREDDMPAP--LSPYAAAKLSSENYCQ---VFQREF 218
Query: 186 AI--ISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDDYPTADG 242
I + LRYFN G +DP + ++P ++S + G + ++G DG
Sbjct: 219 PIETVVLRYFNVFGPR------QDPKSEYSAVIPRFVSMILSG--ERPVIYG------DG 264
Query: 243 TGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXX 302
RD++ V D+A ++ A + G N+G G ++LE++
Sbjct: 265 QQSRDFVFVRDVANANMLAATVADAAG----GIFNVGRGQRTTLLELLDTLRELLEGDIQ 320
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDT 342
GDV ++AD LG+ T + + R +
Sbjct: 321 PIHEPPRAGDVRDSLADTNQIRSRLGFEPTVDMTEGLRQS 360
>UniRef50_A0JYE3 Cluster: NAD-dependent epimerase/dehydratase; n=16;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Arthrobacter sp. (strain FB24)
Length = 364
Score = 70.5 bits (165), Expect = 6e-11
Identities = 51/142 (35%), Positives = 73/142 (51%), Gaps = 15/142 (10%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGGAG++G + L + D +VVVDNL A G++ PE L EL
Sbjct: 14 VLVTGGAGFIGC-AISDALVNEFD----RVVVVDNLHPQIHATGQR-PEQLNAAAELV-- 65
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
D+ A+ D + ++ D VIH AA G+S+E+ + VN+ GT L +
Sbjct: 66 -----VADVTEAKTWDTVLQDVTPDVVIHLAAETGTGQSLEESTRHAHVNVVGTSQLLDG 120
Query: 125 MRKHGVY--KLVYSSSCTVYGE 144
+ +HG ++V SSS VYGE
Sbjct: 121 LNRHGKLPRRIVLSSSRAVYGE 142
>UniRef50_A2EQ76 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 100
Score = 70.1 bits (164), Expect = 8e-11
Identities = 43/91 (47%), Positives = 54/91 (59%), Gaps = 12/91 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+L+TGGAGY+GSHT+I L + D VV DNLSN+ C E+LKR+ ++ K
Sbjct: 3 ILITGGAGYIGSHTLIELFKVGYD-----FVVFDNLSNS-C------DESLKRVSKIINK 50
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFA 95
V F K DIR AL FE + D VIHFA
Sbjct: 51 EVKFVKGDIRDHAALKECFEKYKPDSVIHFA 81
>UniRef50_Q5UXR0 Cluster: UDP-glucose 4-epimerase; n=3;
Halobacteriaceae|Rep: UDP-glucose 4-epimerase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 310
Score = 70.1 bits (164), Expect = 8e-11
Identities = 76/257 (29%), Positives = 114/257 (44%), Gaps = 33/257 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTG GY+GS +I LL D ++VV D+LS+ P AL G
Sbjct: 3 VLVTGACGYIGS-ALIPLLRADDRVD--DVVVFDDLSSG-------SPRALLGT---VGD 49
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ F + DIR E D +D VIH AA+ + E+ E + +N +GT +
Sbjct: 50 GLEFRRGDIR--EYGDVESAMRGVDRVIHLAAITGASSTHERRDETFAINYDGTENVLTA 107
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
K GV +V++SSC VYG I+E+ +PY ++K E ++++ C +
Sbjct: 108 AGKLGVDHVVFASSCNVYGRATSTDIDET--VDPDPINPYAETKLQSETLLQEYC-EEFD 164
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+LR + G P GI NL+ + L V+G DG+
Sbjct: 165 MTGTALRM--------ATNFGHSP-GIRFNLVVNYFVFRALTDRPLTVYG------DGSN 209
Query: 245 VRDYIHVCDLAAGHVQA 261
R +IHV D A + +A
Sbjct: 210 WRPFIHVRDAARAYAEA 226
>UniRef50_Q9WZ98 Cluster: Nucleotide sugar epimerase, putative; n=3;
cellular organisms|Rep: Nucleotide sugar epimerase,
putative - Thermotoga maritima
Length = 346
Score = 69.7 bits (163), Expect = 1e-10
Identities = 77/250 (30%), Positives = 110/250 (44%), Gaps = 30/250 (12%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYC-AEGEKKPEALKRIEEL 61
+ VLVTGGAG VGS+ V LL+ + ++V+DNLS+ Y + P L
Sbjct: 14 KRVLVTGGAGAVGSNLVRRLLDLGA-----FVIVIDNLSSGYTWLLPQDAPNLL------ 62
Query: 62 TGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
F + DI L R+F N + + H AA A SV+ P + VN GT L
Sbjct: 63 ------FIEGDITNDVDLKRVF-NEEPEIIFHLAAFFANQNSVDYPEKDLWVNGFGTLKL 115
Query: 122 FEIMRKHG-VYKLVYSSS-CTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC 179
E R +G V + VY+SS C++Y +P E P +++PY +K E+ +
Sbjct: 116 LEYTRIYGKVERFVYASSGCSIYPSDAPMPFKEDLPISSWMSTPYQITKAL-GELYCNYF 174
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
I R+FN G GE P N + +I +G K L + G T
Sbjct: 175 YKMYDIPITKARFFNSFGP------GEVPGQYRNVIPNFIYWAMLG--KPLPITGTGEET 226
Query: 240 ADGTGVRDYI 249
D T V D +
Sbjct: 227 RDFTYVGDIV 236
>UniRef50_UPI0000E87F7E Cluster: probable
nucleoside-diphosphate-sugar epimerase protein; n=1;
Methylophilales bacterium HTCC2181|Rep: probable
nucleoside-diphosphate-sugar epimerase protein -
Methylophilales bacterium HTCC2181
Length = 309
Score = 69.3 bits (162), Expect = 1e-10
Identities = 69/259 (26%), Positives = 104/259 (40%), Gaps = 28/259 (10%)
Query: 89 DCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKH-GVYKLVYSSSCTVYGEPEY 147
D +IH A +VG S++ PL+ ++ N+N T + E +R + K++ SS VYGE E
Sbjct: 70 DSIIHCAGSGSVGLSIQNPLDDFERNLNTTLNVLEYVRLYASTAKVITISSAGVYGEVEK 129
Query: 148 LPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGED 207
LP+ E SPYG K EE+ K V + LR F+ G
Sbjct: 130 LPMAEGDSINP--ISPYGVHKKIAEELCKSY-VDHFGLNVTVLRLFSVYG---------- 176
Query: 208 PSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQ 267
G+ L+ +G E K FG G +RD+IHV D+A + +
Sbjct: 177 -PGLKKQLLWDACNKIMG--GEYKFFG------TGNELRDWIHVTDVA----KLVACLLT 223
Query: 268 PGFNGFHAINLGTGTGYSVLEMV-AAFSNASGXXXXXXXXXXXXGDVTANVADVALATRS 326
+ F+ N TG G + +++ F+ GD VADV ++
Sbjct: 224 TSSSNFNLYNGATGLGTPITDILKLLFTALDSKESAIFTGSARQGDPIGYVADVTKTSQV 283
Query: 327 LGWRATRSLHDMCRDTWRW 345
L W H + W
Sbjct: 284 LAWDPKIKWHQGVLEYAEW 302
>UniRef50_Q2LWN6 Cluster: NAD dependent epimerase/dehydratase
family; n=1; Syntrophus aciditrophicus SB|Rep: NAD
dependent epimerase/dehydratase family - Syntrophus
aciditrophicus (strain SB)
Length = 318
Score = 69.3 bits (162), Expect = 1e-10
Identities = 71/266 (26%), Positives = 110/266 (41%), Gaps = 26/266 (9%)
Query: 88 IDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVY-SSSCTVYGEPE 146
+D +I A S + P++ N+ + ++ + K+V SS +YG
Sbjct: 72 VDEIIDLAYATVPKTSYDNPIQDILENLPPLVNMLDVASALNLEKIVLISSGGVIYGHSL 131
Query: 147 YLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGE 206
PINE HPT SPYG +K E+ + ++ ++ +R N G + IG+
Sbjct: 132 NTPINEEHPTNP--ISPYGITKLAVEKYARMFHLT-HDLPVVCVRPGNAYGETQKPFIGQ 188
Query: 207 DPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFH 266
+ I+ + G EL ++G+ GT VRDYIHV D+A G V A+ L
Sbjct: 189 ------GFIAAAIASILCG--LELTLYGE-----SGT-VRDYIHVEDIAEGIVAAL-LKG 233
Query: 267 QPGFNGFHAINLGTGTGYS---VLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALA 323
PG N+G+G G + +L+ + + A G DV NV D +
Sbjct: 234 PPG----SIYNIGSGEGRNNRDILDALQPLAQAEGLEVKLKTLPLRKFDVPVNVLDSSRL 289
Query: 324 TRSLGWRATRSLHDMCRDTWRWQEAN 349
+ GW D TW W N
Sbjct: 290 SWDTGWTMRIPFEDGIIRTWNWYRDN 315
>UniRef50_Q2AZL1 Cluster: NAD-dependent epimerase/dehydratase:3-beta
hydroxysteroid dehydrogenase/isomerase:Polysaccharide
biosynthesis protein CapD:dTDP- 4-dehydrorhamnose
reductase:Nucleotide sugar epimerase; n=3; Bacillus
cereus group|Rep: NAD-dependent
epimerase/dehydratase:3-beta hydroxysteroid
dehydrogenase/isomerase:Polysaccharide biosynthesis
protein CapD:dTDP- 4-dehydrorhamnose
reductase:Nucleotide sugar epimerase - Bacillus
weihenstephanensis KBAB4
Length = 307
Score = 68.9 bits (161), Expect = 2e-10
Identities = 55/212 (25%), Positives = 98/212 (46%), Gaps = 25/212 (11%)
Query: 87 NIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVYSSSCTVYGEPE 146
N+D VIH AAL V + +VN GT + E+ ++G+ KL++SSS VYG+
Sbjct: 58 NVDGVIHLAALVGVDNCRSNEEDVVRVNFEGTKNIVEVCIENGIGKLLFSSSSEVYGDGV 117
Query: 147 YLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGE 206
+P E+ K S YGK+K E+ +K+ + K ++ RYFN G+ ++
Sbjct: 118 SVPFKENDV--KIPKSAYGKAKLMSEDFLKEYANNSFKVRVV--RYFNVYGSQQNENF-- 171
Query: 207 DPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFH 266
+ ++ Q G + + ++G DG +R + ++ D+ G + A + +
Sbjct: 172 -------VISKFLKQAHNG--ENMTIYG------DGQQIRCFSYISDIVNGTILAFE-YE 215
Query: 267 QPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
+ F F N+G S+ E+ + G
Sbjct: 216 RENFADF---NIGNNKPISMEELAGKINELMG 244
>UniRef50_Q1ILI4 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=3; Bacteria|Rep: NAD-dependent
epimerase/dehydratase precursor - Acidobacteria
bacterium (strain Ellin345)
Length = 372
Score = 68.9 bits (161), Expect = 2e-10
Identities = 51/149 (34%), Positives = 71/149 (47%), Gaps = 18/149 (12%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M + +LVTGGAG+VGSH V LL + V DNLS G +
Sbjct: 1 MRKRILVTGGAGFVGSHLVDALLRAGH-----SVRVFDNLSPQVHPHG---------LPS 46
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+ F + D+R +A+ R E NID + H AA VG+S+ + Y N GT
Sbjct: 47 YLATDIEFIQGDMRDLDAVRRSLE--NIDVIFHKAAAVGVGQSMYEISHYMSANTQGTAN 104
Query: 121 LFEIM--RKHGVYKLVYSSSCTVYGEPEY 147
L + M + KLV +SS ++YGE +Y
Sbjct: 105 LLQAMLDSRRDFEKLVVASSMSIYGEGKY 133
>UniRef50_A2R6J0 Cluster: Catalytic activity: dTDPglucose =
dTDP-4-dehydro-6-deoxy-D-glucose + H2O; n=1; Aspergillus
niger|Rep: Catalytic activity: dTDPglucose =
dTDP-4-dehydro-6-deoxy-D-glucose + H2O - Aspergillus
niger
Length = 362
Score = 68.9 bits (161), Expect = 2e-10
Identities = 46/142 (32%), Positives = 72/142 (50%), Gaps = 11/142 (7%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+ +LVTGGAG++G V LL Q G ++ D L YCA + +E L
Sbjct: 23 KTILVTGGAGFIGGWFVRHLL--QVYGTKYTVLCFDILD--YCASKRN----FQPVEHLP 74
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
HF+ D+ + + +F+ +D V+HFAA V +S+ PL + + N+ GT L
Sbjct: 75 N--FHFFPGDLCDRDRVTALFQQFKVDAVVHFAANSHVDQSLVNPLSFTRSNVTGTHVLL 132
Query: 123 EIMRKHG-VYKLVYSSSCTVYG 143
E R+ G V + ++ S+ VYG
Sbjct: 133 EAARQAGTVIRFIHISTDEVYG 154
>UniRef50_UPI0000384B58 Cluster: COG0451:
Nucleoside-diphosphate-sugar epimerases; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0451:
Nucleoside-diphosphate-sugar epimerases -
Magnetospirillum magnetotacticum MS-1
Length = 299
Score = 68.5 bits (160), Expect = 2e-10
Identities = 75/254 (29%), Positives = 110/254 (43%), Gaps = 43/254 (16%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTG AG++GSHT+ LL + L++ G + ++L + + G +
Sbjct: 7 LVTGAAGFLGSHTIEALLAQGHRVRGLDL------------PGARFEDSLGALLDHPGLS 54
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
+ K D+ A D IF +D + H A + S++ P Y Q N+ + E
Sbjct: 55 LD--KRDLLDIPADDPIFAG--VDVIYHCAGIADHVPSLQVPERYMQANVMAVVRVLEAA 110
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK- 184
R H V K++ +SS VYG P E HP +PYG +K+ EE C K
Sbjct: 111 RHHKVRKVINASSAAVYGIAA-APTAEDHPINP--VNPYGLTKWMAEE----ACAHWSKV 163
Query: 185 --WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADG 242
A +S R FN G + P G ++ + A G + L V T DG
Sbjct: 164 FGVATLSFRIFNCYGPRAT---ASGPIGF------FLKKAAAG--EALTV------TGDG 206
Query: 243 TGVRDYIHVCDLAA 256
T RD+IHV D+ A
Sbjct: 207 TQERDFIHVSDVVA 220
>UniRef50_Q93KW6 Cluster: Putative NDP-glucose 4-epimerase; n=1;
Streptomyces viridochromogenes|Rep: Putative NDP-glucose
4-epimerase - Streptomyces viridochromogenes
Length = 342
Score = 68.5 bits (160), Expect = 2e-10
Identities = 81/293 (27%), Positives = 123/293 (41%), Gaps = 40/293 (13%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTGGAG++GSH LL R + V+D+LS E+ PE
Sbjct: 5 LVTGGAGFIGSHVAEALLSRGH-----RVSVLDDLSGG---TAERVPEG----------- 45
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
H + + E +DR+F D V HFAA A S Y N+ G+ L
Sbjct: 46 AHLFTGSVTDVELVDRLFAEQRFDHVFHFAAFAAEAISHSVKSLNYGTNVMGSVNLINAA 105
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
+ GV ++SS VYG E P+ ES + YG +K E + + + +
Sbjct: 106 LRTGVSFFCFASSVAVYGHGE-TPMRESSIPVPA--DSYGNAKLTVEREL-ETTMRTQGL 161
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
+ R N G ++ R DP N + + +Q+ G + + V+G DG V
Sbjct: 162 PFTAFRMHNVYGEWQNMR---DP--YRNAVAIFFNQILRG--EPISVYG------DGGQV 208
Query: 246 RDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
R + +V D+ V+A + G A N+G+ +VLE+ A A+G
Sbjct: 209 RAFSYVKDIVDVIVRAPETEKAWG----RAFNVGSSRTNTVLELAQAVRAAAG 257
>UniRef50_A0GDZ4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Burkholderia phytofirmans PsJN|Rep: NAD-dependent
epimerase/dehydratase - Burkholderia phytofirmans PsJN
Length = 314
Score = 68.5 bits (160), Expect = 2e-10
Identities = 64/245 (26%), Positives = 104/245 (42%), Gaps = 22/245 (8%)
Query: 89 DCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGVYKLVYSSS-CTVYGEPEY 147
D V H A G + + PL + N+ GT L E +R+ K++++SS VYG P
Sbjct: 64 DGVFHLAWSTVPGSANKAPLSDLETNLLGTVRLLEAIRQQPNTKILFASSGGAVYGTPTR 123
Query: 148 LPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKWAIIS--LRYFNPVGAHESGRIG 205
+PI+E H +S YG +K E L V ++W + + +R NP G G
Sbjct: 124 IPIDEDH--SRSPLGAYGAAKLAAETY---LDVYRRQWQVDARIMRLSNPYGP------G 172
Query: 206 EDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLF 265
++ +G N I + + + ++G +G VRDY+++ D + +
Sbjct: 173 QNING--NQGAATIFAARAVKQQTIDIWG------EGDIVRDYLYIDDAIDAFSRFMNTD 224
Query: 266 HQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATR 325
N +N+G+G G S+ E++ DV NV DV A
Sbjct: 225 AAVFENAMPVLNVGSGKGISLNEIILTIERILKRKIKVQYSPSRGFDVDVNVLDVTHAYH 284
Query: 326 SLGWR 330
+GWR
Sbjct: 285 LIGWR 289
>UniRef50_Q8THQ2 Cluster: DTDP-glucose 4,6-dehydratase; n=15;
Archaea|Rep: DTDP-glucose 4,6-dehydratase -
Methanosarcina acetivorans
Length = 320
Score = 68.5 bits (160), Expect = 2e-10
Identities = 64/204 (31%), Positives = 94/204 (46%), Gaps = 20/204 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++GS+ V LLE+ + +VV DNLS+ K E ++ +
Sbjct: 11 ILVTGGAGFIGSNLVDRLLEKGN-----LVVVFDNLSSG-------KLEFIE--QHFENP 56
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ D+ EA++R + +D V H AA V + NI T L E
Sbjct: 57 DFSLVRGDLLDPEAIERACTD--VDMVYHVAANPDVKLGASDTKVHLDQNILATYNLLEA 114
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSL-TSPYGKSKYFCEEIMKDLCVSDK 183
MRK K+ ++S+ TVYGE +P E + G + S YG SK CE ++ +
Sbjct: 115 MRKGNAKKIAFTSTSTVYGEASVMPTPEDY--GPLIPISLYGASKLACEALITSYSHTFD 172
Query: 184 KWAIISLRYFNPVGAHESGRIGED 207
A I R+ N VG + I D
Sbjct: 173 MQAWI-FRFANIVGPRSTHGITVD 195
>UniRef50_Q982P5 Cluster: UDP-glucose 4-epimerase; n=1;
Mesorhizobium loti|Rep: UDP-glucose 4-epimerase -
Rhizobium loti (Mesorhizobium loti)
Length = 310
Score = 68.1 bits (159), Expect = 3e-10
Identities = 73/288 (25%), Positives = 122/288 (42%), Gaps = 32/288 (11%)
Query: 64 KTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFE 123
+ + +++ D R A+ + ++H D VIH + + ++ + L +
Sbjct: 43 REIAWFEGDFRDNLAVTKALQSH--DTVIHLVHSTWPSTADADMAADIRDSVIPSVELLD 100
Query: 124 IMRKHGVYKLVY-SSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
+ GV +++Y SS TVYGE + +PI E PT YG SK E ++ + +
Sbjct: 101 ACVRSGVKRIIYFSSGGTVYGEVDEIPIREDSPTNP--VGAYGVSKLMIEHYVR---LYE 155
Query: 183 KKWAIIS--LRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
+K+ + S +R NP G + + +L+ QV V+G
Sbjct: 156 RKYGLNSFIVRLANPFGPWQVEAHNQGLVAFAGHLIQSDRQVT--------VYG------ 201
Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGF-HAINL-GTGTGYSVLEMVAAFSNASG 298
DG+ RDY++V D+A + I +NG N+ G G G S+L+++ A + G
Sbjct: 202 DGSARRDYVYVEDVANFVARLI------NYNGAKRTFNVGGGGNGQSILDVIHAIETSLG 255
Query: 299 XXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQ 346
DV +NV + A + LGWR S D T WQ
Sbjct: 256 KRAMIKREPSRPFDVPSNVLSIERAEKELGWRPATSFPDGIDYTLSWQ 303
>UniRef50_Q54366 Cluster: LmbM protein; n=1; Streptomyces
lincolnensis|Rep: LmbM protein - Streptomyces
lincolnensis
Length = 324
Score = 68.1 bits (159), Expect = 3e-10
Identities = 85/299 (28%), Positives = 126/299 (42%), Gaps = 36/299 (12%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
MS VTGGAG++GSH V T R P E+V D+LSN G +P
Sbjct: 1 MSGRYCVTGGAGFIGSHFVETAPRRGRH--PGEVVAYDDLSNT--TTGGFEPL------- 49
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESV-EKPLEYYQVNINGTC 119
L + + F + D+ L D V+H A+ + + ++ + Q GT
Sbjct: 50 LADERLRFVRADVLDTARLTEELTGWTQDDVVHLASSVDMRKGYHDRGFDLRQC-AEGTL 108
Query: 120 TLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC 179
++ MR G +++SSS TVYG+P LP E H + S YG K E ++ C
Sbjct: 109 SVLNAMRASGPRTVLFSSSSTVYGDPVTLPTPE-HAGPYAPISMYGAGKLAAEALLSANC 167
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
D A + R+ N VG GR+ G+ ++ + + R L+V G
Sbjct: 168 HLDGFTAHV-FRFGNVVG----GRMNH---GVIHDFIEKLD----ARRDRLQVLG----- 210
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
DG ++Y V + G + A GFH +NLG SV E+ A + G
Sbjct: 211 -DGRQRKNYFLVEECVDGILTASGKLGP----GFHVLNLGNPGTVSVDEIAAIVIDEMG 264
>UniRef50_A5TVF5 Cluster: dTDP-glucose 4,6-dehydratase; n=4;
Fusobacterium nucleatum|Rep: dTDP-glucose
4,6-dehydratase - Fusobacterium nucleatum subsp.
polymorphum ATCC 10953
Length = 400
Score = 68.1 bits (159), Expect = 3e-10
Identities = 51/165 (30%), Positives = 85/165 (51%), Gaps = 14/165 (8%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
M + L+TG AG++G++ + +L++ D ++++V D+L+ A K EE
Sbjct: 1 MVKTYLLTGAAGFIGANFLKYILKKYKD---IKVIVADSLTYAGNLGTIK--------EE 49
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
L V F KVDIR + ++RIF + +D V++FAA V S+E P + + NI GT
Sbjct: 50 LKDSRVKFEKVDIREKKEIERIFSENKVDYVVNFAAESHVDRSIENPQVFLETNILGTQN 109
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGE-PEYLPINESHPTGKSLTSPY 164
L + +K + + VY E +YL ++ G SL+ Y
Sbjct: 110 LLDNTKKSWIIS-KDENGYPVYREGVKYLQVSTDEVYG-SLSKDY 152
>UniRef50_A0L3Z4 Cluster: NAD-dependent epimerase/dehydratase; n=3;
Proteobacteria|Rep: NAD-dependent epimerase/dehydratase
- Magnetococcus sp. (strain MC-1)
Length = 310
Score = 68.1 bits (159), Expect = 3e-10
Identities = 87/336 (25%), Positives = 148/336 (44%), Gaps = 46/336 (13%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
L+TGG G++GSH LL R GD + I+ D+LS KR E + G T
Sbjct: 5 LITGGCGFIGSHLADALLAR---GDGVRIL--DDLSTG------------KR-ENVQG-T 45
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
D+ ++ + + + +D H AA+ +V S E + +++N G+ +F+
Sbjct: 46 CEIILGDVADSQTVRQAMQG--VDGCFHLAAVASVARSNEDWVGTHRINQTGSVNVFDAA 103
Query: 126 R--KHGV-YKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSD 182
R K G +VY+SS YG + LPI+E P ++ + YG K E+ +
Sbjct: 104 RHAKDGQPVPVVYASSAATYGACQTLPIHEDAP--RNPLTAYGADK-LGSELHAVVASGV 160
Query: 183 KKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDDYPTAD 241
R+FN G +DPS + ++ + +++ VG +++ +FG D
Sbjct: 161 HGVPTCGFRFFNVYGPR------QDPSSPYSGVISIFTNRMRVG--QDVTIFG------D 206
Query: 242 GTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXX 301
G RD+++V D+ A H+ A + G N+ TG ++L++ +
Sbjct: 207 GGQTRDFVYVADVVA-HLLA-GMDRATG--EAKVYNVCTGREITLLQLALMIRSLLDSKI 262
Query: 302 XXXXXXXXXGDVTANVADVALATRSLGWRATRSLHD 337
GD+ ++ D AT LG RA +L D
Sbjct: 263 AIHHGEPRAGDIRESLGDPRRATAELGVRAEITLED 298
>UniRef50_Q9UXL5 Cluster: DTDP-glucose 4,6-dehydratase; n=1;
Sulfolobus solfataricus|Rep: DTDP-glucose
4,6-dehydratase - Sulfolobus solfataricus
Length = 317
Score = 68.1 bits (159), Expect = 3e-10
Identities = 87/295 (29%), Positives = 128/295 (43%), Gaps = 48/295 (16%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
++V GGAG++GS V L +R ++ +VVD L+ A G K E L G
Sbjct: 3 IIVVGGAGFIGSAFVRELNKR-----GIKPIVVDLLTYA----GRK--------ENLIGT 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
F + D+R +E + I + ++ D VI+FAA V S+ KP ++ N+ GT L E
Sbjct: 46 DYDFVQADVR-SEKMHDIIKEYSPDIVINFAAETHVDRSIYKPQDFVTTNVLGTVNLLEA 104
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
RK +K V+ S+ VYGE +E+ P S SPY SK + +K
Sbjct: 105 SRKFN-FKYVHISTDEVYGEE---CGDENSPLKPS--SPYSASKASADLFVK-------- 150
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDDYPTADGT 243
A + + V S G P P L+P I + +G + V+G DG
Sbjct: 151 -AYVRTYGISAVIVRPSNNYG--PRQFPEKLIPKAIIRTLLG--IHIPVYG------DGK 199
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
RD+I V D A + G N+ G Y+VLE++ SG
Sbjct: 200 AERDWIFVEDTARIIFDVVSRAEWKG----EVYNIPGGQRYNVLEILKMLEEVSG 250
>UniRef50_Q04973 Cluster: Vi polysaccharide biosynthesis protein
vipB/tviC; n=54; Bacteria|Rep: Vi polysaccharide
biosynthesis protein vipB/tviC - Salmonella typhi
Length = 348
Score = 68.1 bits (159), Expect = 3e-10
Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 26/246 (10%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
L+TG AG++GS + LL ++ +DN S Y + + E
Sbjct: 19 LITGVAGFIGSGLLEELLFLNQT-----VIGLDNFSTGY---QHNLDDVRTSVSEEQWSR 70
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
F + DIR + +N +D V+H AAL +V S++ P+ NI+G +
Sbjct: 71 FIFIQGDIRKFTDCQKACKN--VDYVLHQAALGSVPRSLKDPIATNSANIDGFLNMLTAA 128
Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
R V Y++S + YG+ LP E G+ L SPY +KY E+ D+ ++
Sbjct: 129 RDAHVSSFTYAASSSTYGDHPDLPKIEER-IGRPL-SPYAVTKY-VNELYADVFARSYEF 185
Query: 186 AIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTGV 245
I LRYFN G ++P+G + ++P + + LK+ + Y DG+
Sbjct: 186 NAIGLRYFNVFGRR------QNPNGAYSAVIP---RWILSLLKDEPI----YINGDGSTS 232
Query: 246 RDYIHV 251
RD+ ++
Sbjct: 233 RDFCYI 238
>UniRef50_Q81YX3 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=10; Bacillus cereus group|Rep: NAD-dependent
epimerase/dehydratase family protein - Bacillus
anthracis
Length = 321
Score = 67.7 bits (158), Expect = 4e-10
Identities = 67/251 (26%), Positives = 113/251 (45%), Gaps = 30/251 (11%)
Query: 1 MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
MS+ L+TGGAG++GSH L + G + +VDN Y + + E +K I
Sbjct: 1 MSKKCLITGGAGFIGSH-----LAEELVGRGYNVTIVDNF---YKGKNKYHDELMKEIRV 52
Query: 61 LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
+ + + ++ + H D V H AA+ V ++EK +E + N +GT
Sbjct: 53 I--------PISVLDKNSIYELVNQH--DVVFHLAAILGVKTTMEKSIELIETNFDGTRN 102
Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
+ + K G K+V++S+ VYG+ + P +E TS S C+ + + LC+
Sbjct: 103 ILQAALK-GKKKVVFASTSEVYGKAK-PPFSEEGDRLYGATSKIRWSYAICKTLEETLCL 160
Query: 181 --SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYP 238
+ + + +RYFN G + G IP +IS G +++ V+GD
Sbjct: 161 GYALEGLPVTIVRYFNIYGPR--AKDGPYAGVIPR----FISAALQG--EDILVYGDGEQ 212
Query: 239 TADGTGVRDYI 249
T T V D +
Sbjct: 213 TRCFTYVSDAV 223
>UniRef50_Q6E7F2 Cluster: Fcf1; n=1; Escherichia coli|Rep: Fcf1 -
Escherichia coli
Length = 316
Score = 67.7 bits (158), Expect = 4e-10
Identities = 80/335 (23%), Positives = 137/335 (40%), Gaps = 40/335 (11%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VL+TGGAG++G + ++ERQ + +V D +S+ KP++L + E
Sbjct: 8 VLITGGAGFIGKALITEMVERQ-----IPLVSFD-ISD--------KPDSLPELSEYFNW 53
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
Y + + L I HNI VIH A ES + + N+ F+
Sbjct: 54 YKFSYLESSQRIKELHEIVSRHNIKTVIHLATTMFPHESKKNIDKDCLENVYANVCFFKN 113
Query: 125 MRKHGVYKLVYSSS-CTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+ ++G K++++SS TVYG+ + P +E ++ YG SK E ++ +
Sbjct: 114 LYENGCEKIIFASSGGTVYGKSD-TPFSEDDALLPEIS--YGLSKVMTETYLR-FIAKEL 169
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
ISLR NP G E RI IP L + + + + ++
Sbjct: 170 NGKSISLRISNPYG--EGQRIDGKQGVIPIFLNKISNDIPIDIIGSIE------------ 215
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAI-NLGTGTGYSVLEMVAAFSNASGXXXX 302
RDYI++ DL + +++ + G I N+G+G ++ +++
Sbjct: 216 SKRDYIYISDLVQAFMCSLE------YEGHEDIFNIGSGESITLKKLIETIEFKLNKKAV 269
Query: 303 XXXXXXXXGDVTANVADVALATRSLGWRATRSLHD 337
+ + D+ A LGWR T L D
Sbjct: 270 IGFQDPIHTNANGIILDIKRAMAELGWRPTVVLDD 304
>UniRef50_A0LGE9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: NAD-dependent
epimerase/dehydratase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 315
Score = 67.7 bits (158), Expect = 4e-10
Identities = 84/342 (24%), Positives = 139/342 (40%), Gaps = 45/342 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VL+ GG G++GSH + LL + + V+D + +A+ +E +TG
Sbjct: 8 VLLVGGNGFIGSHLIDELLRKG-----YSVRVLDRNPEIF-------RKAVPGVEYVTGS 55
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
+ + EA++ D +IH A S+ P E ++ +
Sbjct: 56 FADLFTL----REAVE------GCDILIHLAHSTVPSTSLNHPEEEVLASVGAFVNMINC 105
Query: 125 MRKHGVYKLVY-SSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDK 183
+ + K+VY SS VYG PE LP+ E K + SPYG +K E+ +
Sbjct: 106 FKHKAIGKIVYFSSGGAVYGNPESLPVFE-EARAKPI-SPYGVAKLMMEKYLYMFSYLYG 163
Query: 184 KWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGT 243
II +R NP G ++ +GE ++P + + + + ++G DG
Sbjct: 164 LEYII-VRPSNPFGPRQN-YMGE------QGVIPIFFRKILDD-ETISIWG------DGK 208
Query: 244 GVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXX 303
G +DY++V DLA V I + GF+ N+ +G G S+L ++ SN G
Sbjct: 209 GTKDYLYVEDLAGAVVSLI----ESGFDK-SIYNISSGIGRSLLSIIDNISNICGKRPNI 263
Query: 304 XXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
DV+ GW T + D T++W
Sbjct: 264 EFVAKRTHDVSNITLSFDKIRNRTGWVPTTTFEDGLIQTFKW 305
>UniRef50_Q97L35 Cluster: FUSION: Nucleoside-diphosphate-sugar
epimerase and GAF domain; n=1; Clostridium
acetobutylicum|Rep: FUSION: Nucleoside-diphosphate-sugar
epimerase and GAF domain - Clostridium acetobutylicum
Length = 725
Score = 67.3 bits (157), Expect = 6e-10
Identities = 86/345 (24%), Positives = 139/345 (40%), Gaps = 46/345 (13%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+L+ GG G++GSH V L + +G + ++DNLS G K +
Sbjct: 3 ILIVGGCGFIGSHVVERLYK---EGH--KTYIIDNLST-----GNLKNVTVPH------- 45
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
FY + I +E+ + +F+ + D VI ++ V + E ++ G L
Sbjct: 46 --KFYNLSIE-SESCEEVFKANKFDAVIDLSS-PVVNTNAEASSFELTPSVKGITNLLNF 101
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
K+GV + +++SS +VYG L I E SPY +KY E
Sbjct: 102 SSKYGVKRFIFASSASVYGN-NNLTIKEEAEINP--LSPYAVNKY-VGEFYTQKWFEIYG 157
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
ISLR N G +S + G N + +I++ + E+ FG DGT
Sbjct: 158 LKTISLRISNVFGPRQSIK------GEGNVVALFINKAL--KSSEIDRFG------DGTQ 203
Query: 245 VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXXXXXX 304
RD+I+V D+ V AI + + G +N+ T T +S+ E++
Sbjct: 204 TRDFIYVEDV----VDAIYKALESDYTG--VLNISTNTEHSLNELIDTLEEFH-PIRKVN 256
Query: 305 XXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEAN 349
GD+ + D + A LGW S T+ W + N
Sbjct: 257 YRLNRSGDIKKSKLDNSKAKTELGWDTKYSFRAALEKTYDWYKKN 301
>UniRef50_Q01T66 Cluster: DTDP-glucose 4,6-dehydratase precursor;
n=2; Bacteria|Rep: DTDP-glucose 4,6-dehydratase
precursor - Solibacter usitatus (strain Ellin6076)
Length = 339
Score = 67.3 bits (157), Expect = 6e-10
Identities = 71/253 (28%), Positives = 110/253 (43%), Gaps = 31/253 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTGGAG++GS + + ++D L +V +D L+ A E + R + G
Sbjct: 3 ILVTGGAGFIGS-AFVRMAIAETD---LHVVNLDKLTYAGNLENLAPVDGSDRYRFVHG- 57
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
DI A ++ D ++HFAA V S+ P + N NGT TL E
Sbjct: 58 -------DICDAALVEATLAEERPDAIVHFAAESHVDRSILSPEPVVRTNYNGTFTLLEA 110
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKK 184
R+ + + V+ S+ VYG E P + +SPY SK + + + V+ K
Sbjct: 111 ARRQKIARFVHVSTDEVYGSLE-APAEADEAYVLNPSSPYSASKAASDLLARSYFVTYKL 169
Query: 185 WAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTADGTG 244
+I+ R N G P P L+P + A+ + L V+G DG
Sbjct: 170 PVLIT-RASNNYG----------PYQFPEKLIPLMIANALDD-QPLPVYG------DGQQ 211
Query: 245 VRDYIHVCDLAAG 257
VRD+++V D G
Sbjct: 212 VRDWLYVYDHCRG 224
>UniRef50_A1IA75 Cluster: CDP-tyvelose-2-epimerase; n=4;
Bacteria|Rep: CDP-tyvelose-2-epimerase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 351
Score = 67.3 bits (157), Expect = 6e-10
Identities = 89/342 (26%), Positives = 131/342 (38%), Gaps = 43/342 (12%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
VLVTGG G++GSH R + + L A A G+ + + L G
Sbjct: 3 VLVTGGCGFLGSHVCEYYARRGDQVVSYDNMTKHELERAGFATGKARNH---NRDFLAGL 59
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V DIR AE L I D ++H AA A+ SVE P N+ GT + E
Sbjct: 60 GVDLVTADIRDAEQL--IDSAAGCDYIVHTAAQPAMTISVEDPALDLSSNVMGTFNVLET 117
Query: 125 MRKHGVYKLVYSSSCTVY------------GEPEYL----PINESHPTGKSLTSPYGKSK 168
R+ K+ +S T++ G+ Y I+E HP + +P SK
Sbjct: 118 ARR---LKVPVASCATIHVYGNRINDTLTEGQARYARQPEAIDEDHPVLEGTLTPLHASK 174
Query: 169 YFCEEIMKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLK 228
E ++ + S R G + G GED + N + + + +
Sbjct: 175 AGAELYVRTY-IETYGVTAASFRLTGIYGPRQFG--GEDHGWVANFAIRSVLK------R 225
Query: 229 ELKVFGDDYPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLE 288
L ++G G VRD + D+ +A F+Q G + I G T S+LE
Sbjct: 226 PLTIYG------TGKQVRDIVFAGDVC----RAFDAFYQKRVPGIYNIGGGPNTAISLLE 275
Query: 289 MVAAFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWR 330
+A +G GD+ V DV+ A LGWR
Sbjct: 276 CIALLEKLNGEKPDIRFGPDRHGDLRYFVCDVSKARSLLGWR 317
>UniRef50_Q00TT7 Cluster: Nucleotide-sugar epimerase; n=2;
Ostreococcus|Rep: Nucleotide-sugar epimerase -
Ostreococcus tauri
Length = 487
Score = 67.3 bits (157), Expect = 6e-10
Identities = 94/354 (26%), Positives = 138/354 (38%), Gaps = 50/354 (14%)
Query: 6 LVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKT 65
LVTGGAG++GS V LL+ + + V+D+LS G A + + G+
Sbjct: 173 LVTGGAGFIGSEVVRQLLD-----IGMRVRVLDDLST-----GSPAKLAFAQAAQKEGRY 222
Query: 66 VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESV-----EKPLEYYQVNINGTCT 120
F K D+R E + R + +D V H AA+ V ++ + L + N+ GT
Sbjct: 223 A-FVKGDVRKYEDVSRAM--NGVDFVFHLAAVSKVKPTLDFGREDVVLACVESNVRGTEN 279
Query: 121 LFEIMRKHGV-----YKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIM 175
+ R + VY S T YG + P +E ++ TSPY +K E++
Sbjct: 280 VLRATRARDSGGDRRARFVYVGSSTYYGN-QPTPFDEERTHLRTTTSPYATTKAQGEDLA 338
Query: 176 KDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGD 235
+ L S + R F G E + V GR GD
Sbjct: 339 R-LYYSLYGVEAVVTRIFMVYGPGEPAEAEQ--------------AVVTGRFFAAASKGD 383
Query: 236 DYP-TADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFS 294
DG+ RD+IHV D A G V A PG N+G+G ++L++ S
Sbjct: 384 ALEIEGDGSQFRDFIHVSDAARGIVLAAFAEGAPG----RTFNIGSGKSTTILDLAKMIS 439
Query: 295 NASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRWQEA 348
D+ +A A R LG+ A SL D R T R + A
Sbjct: 440 K------RHTFVDAREPDLKGTLASTCAAKRVLGFEAKMSLTDYIRKTKRERSA 487
>UniRef50_P14169 Cluster: CDP-paratose 2-epimerase; n=12; cellular
organisms|Rep: CDP-paratose 2-epimerase - Salmonella
typhi
Length = 338
Score = 67.3 bits (157), Expect = 6e-10
Identities = 87/354 (24%), Positives = 140/354 (39%), Gaps = 35/354 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+L+TGG G++GS+ L S G ++++V DNLS + +L E + G
Sbjct: 3 LLITGGCGFLGSNLASFAL---SQG--IDLIVFDNLSRKGATDNLHWLSSLGNFEFVHG- 56
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
DIR + R+ + D H A A+ S++ P +++N+ GT L E
Sbjct: 57 -------DIRNKNDVTRLITKYMPDSCFHLAGQVAMTTSIDNPCMDFEINVGGTLNLLEA 109
Query: 125 MRKHGV-YKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYG---------KSKYFCEEI 174
+R++ ++YSS+ VYG+ E NE+ + P G S Y C +
Sbjct: 110 VRQYNSNCNIIYSSTNKVYGDLEQYKYNETETRYTCVDKPNGYDESTQLDFHSPYGCSKG 169
Query: 175 MKDLCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFG 234
D + D I L V H S G + + + Q AV E+K G
Sbjct: 170 AADQYMLDYA-RIFGLN--TVVFRHSSMYGGRQFATYDQGWVGWFCQKAV----EIK-NG 221
Query: 235 DDYP-TADGTG--VRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVA 291
+ P T G G VRD +H D+ + + A+ + N F+ I S+LE+
Sbjct: 222 INKPFTISGNGKQVRDVLHAEDMISLYFTALANVSKIRGNAFN-IGGTIVNSLSLLELFK 280
Query: 292 AFSNASGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
+ D VAD+ T ++ W S D + + W
Sbjct: 281 LLEDYCNIDMRFTNLPVRESDQRVFVADIKKITNAIDWSPKVSAKDGVQKMYDW 334
>UniRef50_A7TUR9 Cluster: Putative nucleoside-diphosphate-sugar
epimerases; n=1; Streptomyces lividans|Rep: Putative
nucleoside-diphosphate-sugar epimerases - Streptomyces
lividans
Length = 332
Score = 66.9 bits (156), Expect = 8e-10
Identities = 84/341 (24%), Positives = 140/341 (41%), Gaps = 42/341 (12%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
R V+VTG AG++GSH L+ + ++ VD A P A + L
Sbjct: 14 RRVVVTGSAGFIGSHLAHALVRAGT-----TVIGVDRRDPA------TDPTAAANLAGLR 62
Query: 63 GKT-VHFYKVD-IRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPL-EYYQVNINGTC 119
G+ H D + C A+D + + + V H A + V S +Y N+ T
Sbjct: 63 GRPGYHHVTADLLHC--AIDPLL--IDAEAVFHLAGIPGVRPSWGPQFGDYLASNVLATH 118
Query: 120 TLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLC 179
+ E + GV +LV +SS +VYG + E+ + SPY +K E++
Sbjct: 119 RVLEASTRIGVPRLVVASSSSVYGPTDGDASRETDRPNPA--SPYAVTKLAEEQLCLAYA 176
Query: 180 VSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT 239
+++LRYF G + ++ + + A + L+++GD +
Sbjct: 177 ERPVGPGVVALRYFTVYGPRQRA-----------DMFTHRALYAALAGQPLRLYGDGHQR 225
Query: 240 ADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGX 299
D T + D + +AAG V P +G IN+G G+ S+L+++ ++ +G
Sbjct: 226 RDFTYIDDVV-AATIAAGVV--------PNAHG--TINVGGGSNASLLDVINIANSLTGR 274
Query: 300 XXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCR 340
GDV AD A LGW+ LH+ R
Sbjct: 275 EIQLHQDHVRNGDVLLTRADPGRAKEVLGWQPRVDLHNGLR 315
>UniRef50_Q8U170 Cluster: UDP-or dTTP-glucose 4-epimerase or
4-6-dehydratase; n=5; Euryarchaeota|Rep: UDP-or
dTTP-glucose 4-epimerase or 4-6-dehydratase - Pyrococcus
furiosus
Length = 336
Score = 66.9 bits (156), Expect = 8e-10
Identities = 82/349 (23%), Positives = 146/349 (41%), Gaps = 47/349 (13%)
Query: 3 RAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELT 62
+ LVTGGAG++GS L+E + ++ VDN ++ + I LT
Sbjct: 24 KTALVTGGAGFLGSWLCDVLIELGA-----KVYCVDNFASG----------RWENISHLT 68
Query: 63 GKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
+ +F ++ ++ L+ +D + HFA+ + E PLE N GT +
Sbjct: 69 SEE-NFVFIEHDVSKPLE---IREKLDFIFHFASRASPFEFEHYPLEIIDANTLGTRNML 124
Query: 123 EIMRKHGVYKLVYSSSCTVYGEPEYLPINESH-----PTGKSLTSPYGKSKYFCEEIMKD 177
E+ +K+ + +++S+ +YG PE +P E++ P G + S Y +SK E +
Sbjct: 125 ELAKKNNA-RFIFASTSEIYGHPEVVPTPETYWGYVNPIG--IRSCYDESKRLGEALTM- 180
Query: 178 LCVSDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMP-YISQVAVGRLKELKVFGDD 236
+ +R FN G R+ D G+ ++P +ISQ + + VFG
Sbjct: 181 AYYRQFNVDVRIVRIFNTYGP----RMRAD--GVYGRVVPRFISQAL--NEEPITVFG-- 230
Query: 237 YPTADGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNA 296
DG+ R + +V DL G ++ + + G +NLG S+LE+
Sbjct: 231 ----DGSQTRSFCYVTDLITGVLKFAAVENGRG----EVVNLGNPREISILELAYLIKKL 282
Query: 297 SGXXXXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
+ D D++ A + L W+ L + + T +W
Sbjct: 283 TNSDSPIEFHPLPPDDPPRRCPDISKAQKLLNWKPKVELEEGLKKTIKW 331
>UniRef50_Q9LIS3 Cluster: UDP-glucuronate 4-epimerase 6; n=40;
Viridiplantae|Rep: UDP-glucuronate 4-epimerase 6 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 460
Score = 66.9 bits (156), Expect = 8e-10
Identities = 91/354 (25%), Positives = 145/354 (40%), Gaps = 40/354 (11%)
Query: 4 AVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTG 63
+VLVTG AG+VGSH + L +R DG ++ DN ++ Y P + +EL
Sbjct: 113 SVLVTGAAGFVGSHCSLALRKR-GDG----VLGFDNFNDYY------DPSLKRARQELLE 161
Query: 64 K-TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLF 122
K V + D+ L ++F+ ++H AA V +++ P Y NI G L
Sbjct: 162 KQQVFIVEGDLNDGPLLRKLFDVVPFTHILHLAAQAGVRYAMKNPQSYIASNIAGFVNLL 221
Query: 123 EIMRKHGVY-KLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVS 181
E+ + +V++SS +VYG P +E H T + S Y +K EEI
Sbjct: 222 EVAKAANPQPAIVWASSSSVYGLNTENPFSEEHRTDQP-ASLYAATKKAGEEIAHTY-NH 279
Query: 182 DKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTAD 241
++ LR+F G P G P+ + ++ + K + D Y T D
Sbjct: 280 IYGLSLTGLRFFTVYG----------PWGRPDMAYFFFTK-DILHGKSI----DIYRTQD 324
Query: 242 GTGV-RDYIHVCDLAAGHVQAIKLFHQPGFNG--------FHAINLGTGTGYSVLEMVAA 292
V RD+ ++ D+ G V A+ + +G NLG + V +V+
Sbjct: 325 NQEVARDFTYIDDIVKGCVGALDTAEKSTGSGGKKRGQAQLRVYNLGNTSPVPVGRLVSI 384
Query: 293 FSNASGXXXXXXXXXX-XXGDVTANVADVALATRSLGWRATRSLHDMCRDTWRW 345
G GDV A+V+LA + G++ T L R +W
Sbjct: 385 LEGLLGTKAKKHLIKMPRNGDVPYTHANVSLAYKDFGYKPTTDLAAGLRKFVKW 438
>UniRef50_Q2JCE7 Cluster: DTDP-glucose 4,6-dehydratase; n=5;
Bacteria|Rep: DTDP-glucose 4,6-dehydratase - Frankia sp.
(strain CcI3)
Length = 357
Score = 66.5 bits (155), Expect = 1e-09
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 13/140 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+LVTG AG++GS+ V R + +V +D L+ A C E + ++ +
Sbjct: 27 LLVTGAAGFIGSNFVRYWRTRHPED---AVVALDALTYAGCREN---------LADVADR 74
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
V F DIR E ++ + H++D V++FAA ++ +P E++ N+ GT TL E
Sbjct: 75 -VTFVHGDIRDQELVESVLREHSVDVVVNFAAESHNSLAIIRPGEFFATNVMGTQTLLEA 133
Query: 125 MRKHGVYKLVYSSSCTVYGE 144
R GV + S+C VYG+
Sbjct: 134 ARTVGVARFHQISTCEVYGD 153
>UniRef50_Q1Q6W8 Cluster: Similar to uridine 5'-diphospho-glucose
4-epimerase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to uridine
5'-diphospho-glucose 4-epimerase - Candidatus Kuenenia
stuttgartiensis
Length = 320
Score = 66.5 bits (155), Expect = 1e-09
Identities = 49/168 (29%), Positives = 82/168 (48%), Gaps = 16/168 (9%)
Query: 5 VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
+L+TGGAG++GSH + LL++ ++ VDNL Y G K E +K +L +
Sbjct: 7 ILITGGAGFIGSHLIDLLLDKD-----FKVTCVDNL---YL--GRK--ENIKH--QLHNE 52
Query: 65 TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEI 124
FYK D+ + L+ IF D + H A + +S + ++N T + E
Sbjct: 53 NFAFYKFDVLNFKKLNDIFRKERFDAIFHLVANSDIKQSAAQTDLDLKLNFMSTYNVLEA 112
Query: 125 MRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCE 172
MR + V ++V++S+ ++GE + + + P S YG SK E
Sbjct: 113 MRLNNVNQIVFASTSAIFGETDEVITEDMGPL--IPISFYGASKLAAE 158
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.319 0.136 0.418
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 415,080,462
Number of Sequences: 1657284
Number of extensions: 17500217
Number of successful extensions: 39320
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 422
Number of HSP's successfully gapped in prelim test: 496
Number of HSP's that attempted gapping in prelim test: 37628
Number of HSP's gapped (non-prelim): 1367
length of query: 356
length of database: 575,637,011
effective HSP length: 102
effective length of query: 254
effective length of database: 406,594,043
effective search space: 103274886922
effective search space used: 103274886922
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 73 (33.5 bits)
- SilkBase 1999-2023 -