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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001383-TA|BGIBMGA001383-PA|IPR005886|UDP-glucose
4-epimerase, IPR001509|NAD-dependent epimerase/dehydratase
         (356 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_30795| Best HMM Match : Epimerase (HMM E-Value=0)                  381   e-106
SB_42322| Best HMM Match : No HMM Matches (HMM E-Value=.)              57   2e-08
SB_32547| Best HMM Match : Epimerase (HMM E-Value=3.2e-08)             46   4e-05
SB_15042| Best HMM Match : No HMM Matches (HMM E-Value=.)              43   4e-04
SB_45592| Best HMM Match : Epimerase (HMM E-Value=1.4e-19)             38   0.016
SB_32433| Best HMM Match : NAD_binding_4 (HMM E-Value=0.037)           37   0.029
SB_45640| Best HMM Match : Epimerase (HMM E-Value=9.4e-38)             36   0.038
SB_27528| Best HMM Match : Epimerase (HMM E-Value=3.2e-06)             31   1.4  
SB_37976| Best HMM Match : Tubulin (HMM E-Value=4.5e-18)               30   2.5  
SB_11668| Best HMM Match : rve (HMM E-Value=6.2e-14)                   29   4.4  
SB_28495| Best HMM Match : No HMM Matches (HMM E-Value=.)              29   5.8  
SB_23844| Best HMM Match : RRM_2 (HMM E-Value=4.8)                     29   7.6  
SB_14386| Best HMM Match : Ion_trans_2 (HMM E-Value=2.4e-11)           29   7.6  

>SB_30795| Best HMM Match : Epimerase (HMM E-Value=0)
          Length = 869

 Score =  381 bits (937), Expect = e-106
 Identities = 187/339 (55%), Positives = 238/339 (70%), Gaps = 15/339 (4%)

Query: 1   MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEE 60
           MS+ VLVTGGAGY+GSH V+ +L         E+V++DNLSN+         E ++R+EE
Sbjct: 37  MSKKVLVTGGAGYIGSHCVVEILNAG-----YEVVIIDNLSNS-------DAECVRRVEE 84

Query: 61  LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
           ++GK V F+  D+   EALD IF+ H  + V+HFA LKAVGESV+ PL YY  N+ GT  
Sbjct: 85  ISGKKVPFFIEDLLNKEALDDIFKKHKFNGVLHFAGLKAVGESVQIPLRYYHNNLTGTLH 144

Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCV 180
           L E M+KHGV+ LV+SSS TVYG+P++LPI ESHP G   T+PYGK+KYF EE++KDLC 
Sbjct: 145 LLECMKKHGVHNLVFSSSATVYGDPQFLPITESHPAG-GCTNPYGKTKYFIEEMLKDLCY 203

Query: 181 SDKKWAIISLRYFNPVGAHESGRIGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPTA 240
           ++K++ I+SLRYFNPVGAH+SG+IGEDP  IPNNL+PYI+QVAVG+   L VFG DY T 
Sbjct: 204 AEKEFNIVSLRYFNPVGAHKSGKIGEDPKDIPNNLLPYITQVAVGKRPHLNVFGKDYDTP 263

Query: 241 DGTGVRDYIHVCDLAAGHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASGXX 300
           DGTGVRDYIHV DLA GHV A+K   +    G+   NLGTG GYSVLEMV A   ASG  
Sbjct: 264 DGTGVRDYIHVVDLAMGHVAALKKVEEK--CGWKVYNLGTGRGYSVLEMVKAVEKASGKE 321

Query: 301 XXXXXXXXXXGDVTANVADVALATRSLGWRATRSLHDMC 339
                     GD+ +  AD +LA + L W+ATR+ ++MC
Sbjct: 322 IPYKFTDRRAGDIASCYADPSLAAKELNWKATRAQNEMC 360


>SB_42322| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 294

 Score = 57.2 bits (132), Expect = 2e-08
 Identities = 40/135 (29%), Positives = 62/135 (45%), Gaps = 1/135 (0%)

Query: 66  VHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTLFEIM 125
           ++  K DI  A  L  IF+   ID V+HFAA   V  S    L++ + N+ GT  L  + 
Sbjct: 50  INLDKGDICEANHLKYIFQAEQIDTVLHFAAQSHVDNSFWSSLDFTKTNVYGTHVLINVA 109

Query: 126 RKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIMKDLCVSDKKW 185
            +  + K ++ S+  VYG    L    S  +    ++PY  SK   E I+    +   K+
Sbjct: 110 HEAKIKKFIHVSTDEVYGGNSSLGDMHSESSPLRPSNPYAASKAAAECIVMSY-LESFKF 168

Query: 186 AIISLRYFNPVGAHE 200
            +I  R  N  G H+
Sbjct: 169 PVIITRSNNVYGPHQ 183


>SB_32547| Best HMM Match : Epimerase (HMM E-Value=3.2e-08)
          Length = 327

 Score = 46.4 bits (105), Expect = 4e-05
 Identities = 35/102 (34%), Positives = 52/102 (50%), Gaps = 5/102 (4%)

Query: 72  DIRCAEALDRIFENHNIDCVIHFAA-LKAVGESVEKPLEYYQVNINGTCTLFEIMRKHGV 130
           D+   ++L  I  NHNID ++HF+A L AVGE  +   +  QVNI G   + E  RK+ +
Sbjct: 80  DVLDPQSLQSIVVNHNIDWIVHFSAILSAVGE--QNVTQALQVNIEGFHNIIETCRKYNL 137

Query: 131 YKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCE 172
            +L   S+   +G PE    N    T +   + YG +K   E
Sbjct: 138 -RLFSPSTIGAFG-PETPMDNTPDITIQRPKTIYGVAKVHME 177


>SB_15042| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 45

 Score = 42.7 bits (96), Expect = 4e-04
 Identities = 23/42 (54%), Positives = 26/42 (61%), Gaps = 2/42 (4%)

Query: 257 GHVQAIKLFHQPGFNGFHAINLGTGTGYSVLEMVAAFSNASG 298
           GHV A+K   +    G+   NLGTG GYSVLEMV A   ASG
Sbjct: 2   GHVAALKKVEEKC--GWKVYNLGTGRGYSVLEMVKAVEKASG 41


>SB_45592| Best HMM Match : Epimerase (HMM E-Value=1.4e-19)
          Length = 672

 Score = 37.5 bits (83), Expect = 0.016
 Identities = 47/175 (26%), Positives = 82/175 (46%), Gaps = 22/175 (12%)

Query: 5   VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
           VLVTG +G++  H V  LLE   +G  +    V +LS       +KK + L+ +   +  
Sbjct: 18  VLVTGASGFIACHVVKQLLE---EGKFIVRGTVRDLS------VDKKVQPLRNLCPDSK- 67

Query: 65  TVHFYKVDIRCAEALDRI-FENHNIDC--VIHFAA-LKAVGESVEKPLEYYQVNINGTCT 120
               Y ++I  A+ +D + +E    DC  V+H A+   A    +E   +  +  + GT +
Sbjct: 68  ----YPLEIVEADLMDEVCWERAAKDCQYVLHMASPFPASNPKLES--DIIEPAVEGTRS 121

Query: 121 LFEIMRKHGVYKLVYSSSCTV--YGEPEYLPINESHPTGKSLTSPYGKSKYFCEE 173
           + +   K GV ++V +SS     +G  +   + E   + +S   PY KSK   E+
Sbjct: 122 VLKACAKCGVKRVVLTSSIAAVSFGHDDSRVLTEEDWSIESECFPYAKSKLLAEK 176


>SB_32433| Best HMM Match : NAD_binding_4 (HMM E-Value=0.037)
          Length = 116

 Score = 36.7 bits (81), Expect = 0.029
 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 10/117 (8%)

Query: 5   VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGK 64
           +LVTGG G VGSH +  L  +      L I  +     +              ++EL  K
Sbjct: 2   ILVTGGTGLVGSHLLYELALKN-----LPIKAIYRTKESLATVKRVFSYFTTNVDELFNK 56

Query: 65  TVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCTL 121
            + + + DI    +LD  F+   +  V H AAL +      + +   QVNI+GT  +
Sbjct: 57  -IQWIQADITDVPSLDEAFK--EVTLVYHAAALVSFNSKDYRAMR--QVNIDGTANM 108


>SB_45640| Best HMM Match : Epimerase (HMM E-Value=9.4e-38)
          Length = 451

 Score = 36.3 bits (80), Expect = 0.038
 Identities = 52/176 (29%), Positives = 78/176 (44%), Gaps = 31/176 (17%)

Query: 5   VLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDN----LSNAY-CAEGEKKPEALKRIE 59
           VLVTGGAGY+GS  V  LL++       ++ V D     +S+ Y CA          R++
Sbjct: 143 VLVTGGAGYLGSSLVPILLDQG-----YKVTVYDRFLWGISSLYPCASNP-------RLQ 190

Query: 60  ELTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTC 119
            + G        DI     L +       D VIH A++       + P +  +VN  GT 
Sbjct: 191 IING--------DILDVGHLSQCISE--CDAVIHLASIVGYPACEKDPQKATEVNEQGTR 240

Query: 120 TLFEIMRKHGVYKLVYSSSCTVYGEPEYLPINESHPTGKSLTSPYGKSKYFCEEIM 175
            + + +       LVY+S+ + YG  E     ES P   S  + YGK+K   EE++
Sbjct: 241 NVVDALLPG--QPLVYASTGSCYGAIEDGLCTESTPI--SPLTLYGKTKANGEEMV 292


>SB_27528| Best HMM Match : Epimerase (HMM E-Value=3.2e-06)
          Length = 441

 Score = 31.1 bits (67), Expect = 1.4
 Identities = 43/177 (24%), Positives = 74/177 (41%), Gaps = 23/177 (12%)

Query: 2   SRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEK-KPEALKRIEE 60
           +R VLV GG G++GS  V  L+++   GD + IV   N  N Y    E+ KP        
Sbjct: 25  TRRVLVFGGNGFIGSEVVSRLIKQ---GDDITIV---NRGNWYFDSKERIKPYTSTHYRC 78

Query: 61  LTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGESVEKPLEYYQVNINGTCT 120
              K +H     + C E L   F     D V+ F++  ++   +++ LE ++  +     
Sbjct: 79  DRDKALH-----LECPELLTSGF----YDIVLDFSSYTSL--QIKQVLETFKERVG---- 123

Query: 121 LFEIMRKHGVYKLVYSSSCTVYGEPEYL-PINESHPTGKSLTSPYGKSKYFCEEIMK 176
           L+  +    VY++          E + + P +         +  YG  K  CEE ++
Sbjct: 124 LYIYISSDSVYEVCDKKHKGPSREEDAVRPKSPKKRLKLKKSEEYGHEKLACEEALR 180


>SB_37976| Best HMM Match : Tubulin (HMM E-Value=4.5e-18)
          Length = 553

 Score = 30.3 bits (65), Expect = 2.5
 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 2/57 (3%)

Query: 1  MSRAVLVTGGAGYVGSHTVITLLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKR 57
          MS  +L  G  G    H ++TL+E+Q +G PL     D      C + E K  A  R
Sbjct: 1  MSSILLPVGQCGNQIGHELMTLVEKQCEGKPLS--HRDGKLRCVCVDSESKVIASNR 55


>SB_11668| Best HMM Match : rve (HMM E-Value=6.2e-14)
          Length = 597

 Score = 29.5 bits (63), Expect = 4.4
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 3/54 (5%)

Query: 22  LLERQSDGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKTVHFYKVDIRC 75
           LL  +    PL+I+V    S A+ A+G +  +A+K  + L G+    YKV + C
Sbjct: 413 LLNGRQIRTPLDILVP---SPAHQAQGRQDKQAVKAAQRLAGRQDRRYKVGMAC 463


>SB_28495| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 6753

 Score = 29.1 bits (62), Expect = 5.8
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)

Query: 28   DGDPLEIVVVDNLSNAYCAEGEKKPEALKRIEELTGKTVHFYKVDIRCAEALDRIFENHN 87
            DG PLE  V DNL++    E +K P+    +  +  + +  Y V   C E L+ I ++ N
Sbjct: 6473 DGLPLENFVDDNLNDDDDTEAQKTPQRYMLLANVINEQMKQYAV---CNEDLNEIQQDMN 6529


>SB_23844| Best HMM Match : RRM_2 (HMM E-Value=4.8)
          Length = 190

 Score = 28.7 bits (61), Expect = 7.6
 Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 53  EALKRIEELTGKTVHFYKVDIRCAEALDRIFENHNIDCVIHFAALKAVGES-VEKPLEYY 111
           E+LK    L+   +HFY +   CA  L ++  N+    ++H    K +G++ V    E  
Sbjct: 34  ESLKNNSTLSTIGIHFYSLGDACASELAKVLVNNTSLNIVHIGG-KYLGDAGVASIAEAL 92

Query: 112 QVN 114
           +VN
Sbjct: 93  KVN 95


>SB_14386| Best HMM Match : Ion_trans_2 (HMM E-Value=2.4e-11)
          Length = 556

 Score = 28.7 bits (61), Expect = 7.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 9/104 (8%)

Query: 149 PINESHPTGKSLTSPYGKSKYFCEEIMKDLCV-----SDKKWAIISLRYFNPVGAHESGR 203
           P  E+    K  T P GK KYF     K          DK   + ++ +   +GA  SG 
Sbjct: 409 PKLETKEIEKEFTKPSGKIKYFLGHDYKKAQTYTNRYVDKSQLVRNIEHQFSIGAVVSGN 468

Query: 204 IGEDPSGIPNNLMPYISQVAVGRLKELKVFGDDYPT-ADGTGVR 246
            G     I          +A+   +E KV G + PT +DGTG++
Sbjct: 469 FGIAQDFILCLHREITDMIAI---EEAKVTGVEDPTNSDGTGLQ 509


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.319    0.136    0.418 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 12,450,102
Number of Sequences: 59808
Number of extensions: 516477
Number of successful extensions: 953
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 942
Number of HSP's gapped (non-prelim): 15
length of query: 356
length of database: 16,821,457
effective HSP length: 83
effective length of query: 273
effective length of database: 11,857,393
effective search space: 3237068289
effective search space used: 3237068289
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 61 (28.7 bits)

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