Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001367-TA|BGIBMGA001367-PA|IPR001395|Aldo/keto reductase
(331 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 310 3e-83
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 284 3e-75
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 270 3e-71
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 265 1e-69
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 259 6e-68
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 259 8e-68
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 244 3e-63
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 244 3e-63
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 241 2e-62
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 239 7e-62
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 238 1e-61
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 236 5e-61
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 235 1e-60
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 234 2e-60
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 234 2e-60
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 234 3e-60
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 232 8e-60
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 232 1e-59
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 230 3e-59
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 227 4e-58
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 223 4e-57
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 221 2e-56
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 221 2e-56
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 221 2e-56
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 217 2e-55
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 217 3e-55
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 216 6e-55
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 215 1e-54
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 215 2e-54
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 214 2e-54
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 212 9e-54
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 211 2e-53
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 210 4e-53
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 209 7e-53
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 209 7e-53
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 209 9e-53
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 209 9e-53
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 207 3e-52
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 206 5e-52
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 206 8e-52
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 206 8e-52
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 204 3e-51
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 204 3e-51
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 203 4e-51
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 203 6e-51
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 202 1e-50
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 201 2e-50
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 201 2e-50
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 200 5e-50
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 199 7e-50
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 199 9e-50
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 198 1e-49
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 198 2e-49
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 197 3e-49
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 197 4e-49
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 196 5e-49
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 196 7e-49
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 196 7e-49
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 195 1e-48
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 195 1e-48
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 195 1e-48
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 195 2e-48
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 195 2e-48
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 194 2e-48
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 194 3e-48
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 194 3e-48
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 192 1e-47
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 192 1e-47
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 192 1e-47
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 191 2e-47
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 191 2e-47
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 190 4e-47
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 190 4e-47
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 190 6e-47
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 189 8e-47
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 189 1e-46
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 187 3e-46
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 187 3e-46
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 187 3e-46
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 187 4e-46
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 187 4e-46
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 186 7e-46
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 186 9e-46
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 185 1e-45
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 185 2e-45
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 184 3e-45
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 182 9e-45
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 182 9e-45
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 182 9e-45
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 182 9e-45
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 182 2e-44
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 181 2e-44
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 180 3e-44
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 180 5e-44
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 180 6e-44
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 179 8e-44
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 178 1e-43
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 178 2e-43
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 178 2e-43
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 177 2e-43
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 177 3e-43
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 177 4e-43
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 176 6e-43
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 176 8e-43
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 175 1e-42
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 175 1e-42
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 175 2e-42
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 174 2e-42
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 174 2e-42
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 174 3e-42
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 173 4e-42
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 173 5e-42
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 173 7e-42
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 173 7e-42
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 172 9e-42
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 172 9e-42
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 172 1e-41
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 172 1e-41
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 171 2e-41
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 171 2e-41
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 171 2e-41
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 171 3e-41
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 171 3e-41
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 169 7e-41
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 169 7e-41
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 169 9e-41
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 169 9e-41
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 169 9e-41
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 169 1e-40
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 168 2e-40
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 168 2e-40
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 168 2e-40
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 168 2e-40
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 167 3e-40
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 167 5e-40
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 166 6e-40
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 166 6e-40
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 166 6e-40
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 166 6e-40
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 165 1e-39
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 165 2e-39
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 164 2e-39
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 164 2e-39
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 164 2e-39
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 164 3e-39
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 163 4e-39
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 163 4e-39
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 163 4e-39
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 163 7e-39
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 163 7e-39
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 161 2e-38
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 161 2e-38
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 161 2e-38
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 161 2e-38
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 160 4e-38
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 160 4e-38
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 160 4e-38
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 160 4e-38
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 160 4e-38
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 160 5e-38
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 159 7e-38
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 159 7e-38
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 159 7e-38
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 159 9e-38
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 159 1e-37
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 159 1e-37
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 158 2e-37
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 158 2e-37
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 158 2e-37
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 158 2e-37
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 158 2e-37
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 158 2e-37
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 158 2e-37
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 158 2e-37
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 157 3e-37
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 157 4e-37
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 157 5e-37
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 157 5e-37
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 156 9e-37
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 156 9e-37
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 155 1e-36
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 155 2e-36
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 155 2e-36
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 155 2e-36
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 155 2e-36
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 154 3e-36
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 154 3e-36
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 154 3e-36
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 153 8e-36
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 153 8e-36
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 153 8e-36
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 152 1e-35
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 152 1e-35
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 151 2e-35
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 151 2e-35
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 151 2e-35
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 151 3e-35
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 151 3e-35
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 151 3e-35
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 149 7e-35
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 149 1e-34
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 149 1e-34
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 149 1e-34
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 149 1e-34
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 149 1e-34
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 147 3e-34
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 147 4e-34
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 146 5e-34
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 146 7e-34
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 146 7e-34
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 145 2e-33
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 144 3e-33
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 144 4e-33
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 144 4e-33
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 143 6e-33
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 142 1e-32
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 141 3e-32
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 141 3e-32
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 141 3e-32
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 140 5e-32
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 140 6e-32
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 139 8e-32
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 139 8e-32
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 138 2e-31
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 138 2e-31
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 137 3e-31
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 136 6e-31
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 136 7e-31
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 135 1e-30
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 135 1e-30
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 135 2e-30
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 135 2e-30
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 134 2e-30
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 133 5e-30
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 133 5e-30
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 133 7e-30
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 132 9e-30
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 132 1e-29
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 132 1e-29
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 132 1e-29
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 130 5e-29
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 130 5e-29
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 130 6e-29
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 128 1e-28
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 127 3e-28
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 127 3e-28
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 127 5e-28
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 127 5e-28
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 126 6e-28
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 126 6e-28
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 126 6e-28
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 126 6e-28
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 126 1e-27
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 125 2e-27
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 123 6e-27
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 123 7e-27
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 122 1e-26
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 120 4e-26
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 119 9e-26
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 119 1e-25
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 119 1e-25
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 118 2e-25
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 118 2e-25
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 117 5e-25
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 116 9e-25
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 115 1e-24
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 115 1e-24
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 114 3e-24
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 113 5e-24
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 113 6e-24
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 112 1e-23
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 111 2e-23
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 111 2e-23
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 111 3e-23
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 111 3e-23
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 110 6e-23
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 108 2e-22
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 108 2e-22
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 107 5e-22
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 106 7e-22
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 106 9e-22
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 105 2e-21
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 105 2e-21
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 105 2e-21
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 104 3e-21
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 104 4e-21
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 103 5e-21
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 103 5e-21
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 103 6e-21
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 101 3e-20
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 101 3e-20
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 100 5e-20
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 100 6e-20
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 99 8e-20
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 99 8e-20
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 100 1e-19
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 100 1e-19
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 99 2e-19
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 99 2e-19
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 98 3e-19
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 97 6e-19
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 97 7e-19
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 97 7e-19
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 97 7e-19
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 95 2e-18
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 95 2e-18
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 95 2e-18
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 94 4e-18
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 94 5e-18
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 93 1e-17
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 91 4e-17
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 91 4e-17
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 90 6e-17
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 90 6e-17
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 89 1e-16
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 89 1e-16
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 88 3e-16
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 88 3e-16
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 87 6e-16
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 87 8e-16
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 86 1e-15
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 85 2e-15
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 85 2e-15
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 85 3e-15
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 84 4e-15
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 84 6e-15
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 84 6e-15
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 84 6e-15
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 83 1e-14
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 83 1e-14
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 83 1e-14
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 82 2e-14
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 81 4e-14
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 81 5e-14
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 81 5e-14
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 81 5e-14
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 79 1e-13
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 79 2e-13
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 78 4e-13
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 77 6e-13
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 76 1e-12
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 76 1e-12
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 75 3e-12
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 75 3e-12
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 75 3e-12
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 73 1e-11
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 72 2e-11
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 72 2e-11
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 72 2e-11
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 72 2e-11
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 71 3e-11
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 70 7e-11
UniRef50_A2UBY5 Cluster: Plant-metabolite dehydrogenase; n=1; Ba... 70 1e-10
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 70 1e-10
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 69 1e-10
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 69 1e-10
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 69 2e-10
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 69 2e-10
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 69 2e-10
UniRef50_Q9F3N3 Cluster: Putative oxidoreductase; n=3; Actinomyc... 69 2e-10
UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket... 69 2e-10
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 68 3e-10
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 68 4e-10
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 67 5e-10
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 67 5e-10
UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 67 5e-10
UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 66 9e-10
UniRef50_Q5ZRR0 Cluster: Aldo/keto reductase; n=3; Legionella pn... 66 1e-09
UniRef50_A1CGI8 Cluster: Aldo-keto reductase (AKR13), puatative;... 66 2e-09
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 65 2e-09
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 65 2e-09
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 65 2e-09
UniRef50_A6BFM9 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 65 2e-09
UniRef50_Q1IPE6 Cluster: Aldo/keto reductase; n=21; Bacteria|Rep... 64 4e-09
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 64 4e-09
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 64 5e-09
UniRef50_Q1GSJ8 Cluster: Aldo/keto reductase; n=3; Sphingomonada... 63 8e-09
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 63 1e-08
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 63 1e-08
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 63 1e-08
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 62 1e-08
UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc... 62 2e-08
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 62 2e-08
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 62 3e-08
UniRef50_A3I2P1 Cluster: Putative oxidoreductase-possibly Aldo/k... 62 3e-08
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 61 3e-08
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 61 4e-08
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 61 4e-08
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 61 4e-08
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 60 6e-08
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 60 6e-08
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 60 6e-08
UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 60 6e-08
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 60 8e-08
UniRef50_Q3WFS8 Cluster: Aldo/keto reductase; n=1; Frankia sp. E... 60 8e-08
UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol... 60 8e-08
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 60 8e-08
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 60 8e-08
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 60 1e-07
UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 60 1e-07
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 60 1e-07
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 60 1e-07
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 59 1e-07
UniRef50_A5GVR8 Cluster: Possible oxidoreductase; n=14; Cyanobac... 59 1e-07
UniRef50_Q9VGF3 Cluster: CG18547-PA; n=7; Endopterygota|Rep: CG1... 59 1e-07
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe... 59 1e-07
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 59 2e-07
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 59 2e-07
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 59 2e-07
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 59 2e-07
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 59 2e-07
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 58 2e-07
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 58 2e-07
UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 58 2e-07
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 58 2e-07
UniRef50_Q2UCK9 Cluster: Predicted oxidoreductases; n=16; Pezizo... 58 2e-07
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_Q84M96 Cluster: At1g60680; n=19; cellular organisms|Rep... 58 3e-07
UniRef50_A7Q5Z6 Cluster: Chromosome chr14 scaffold_54, whole gen... 58 3e-07
UniRef50_Q7VG62 Cluster: Aldo-keto reductase; n=2; Helicobacter|... 58 4e-07
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 58 4e-07
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 58 4e-07
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 57 6e-07
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 57 6e-07
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 57 6e-07
UniRef50_Q8ZYV2 Cluster: Oxidoreductase, conjectural; n=3; Pyrob... 57 6e-07
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 57 6e-07
UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 57 7e-07
UniRef50_Q14722 Cluster: Voltage-gated potassium channel subunit... 57 7e-07
UniRef50_UPI0000E87D03 Cluster: Aldo/keto reductase; n=1; Methyl... 56 1e-06
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 56 1e-06
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 56 1e-06
UniRef50_A1SCW7 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 56 1e-06
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 56 2e-06
UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy... 55 2e-06
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 55 2e-06
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 55 2e-06
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 55 2e-06
UniRef50_A6XQ31 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06
UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 55 2e-06
UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1... 55 3e-06
UniRef50_A6E9U0 Cluster: Oxidoreductase; n=1; Pedobacter sp. BAL... 55 3e-06
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 54 4e-06
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 54 4e-06
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 54 4e-06
UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob... 54 4e-06
UniRef50_A3YG17 Cluster: Oxidoreductase; n=1; Marinomonas sp. ME... 54 4e-06
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 54 5e-06
UniRef50_Q1GJE2 Cluster: Aldo/keto reductase; n=12; Alphaproteob... 54 5e-06
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 54 5e-06
UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam... 54 5e-06
UniRef50_Q39151 Cluster: K+ channel protein; n=29; cellular orga... 54 5e-06
UniRef50_Q4SFJ7 Cluster: Chromosome 7 SCAF14601, whole genome sh... 54 7e-06
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 54 7e-06
UniRef50_Q2CFE8 Cluster: Putative oxidoreductase; n=2; Rhodobact... 54 7e-06
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 54 7e-06
UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 54 7e-06
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 54 7e-06
UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 54 7e-06
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 54 7e-06
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 53 9e-06
UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 53 1e-05
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 53 1e-05
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 53 1e-05
UniRef50_A5V463 Cluster: Aldo/keto reductase; n=1; Sphingomonas ... 53 1e-05
UniRef50_A0C161 Cluster: Chromosome undetermined scaffold_141, w... 53 1e-05
UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 53 1e-05
UniRef50_Q6CI80 Cluster: Similar to tr|O59826 Schizosaccharomyce... 53 1e-05
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 53 1e-05
UniRef50_Q8YUM4 Cluster: Aldo/keto reductase; n=4; Nostocaceae|R... 52 2e-05
UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 52 2e-05
UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam... 52 2e-05
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 52 2e-05
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 52 3e-05
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 52 3e-05
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 52 3e-05
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 52 3e-05
UniRef50_UPI00015B403B Cluster: PREDICTED: similar to CG18547-PA... 51 4e-05
UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;... 51 4e-05
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 51 4e-05
UniRef50_Q096Q3 Cluster: Oxidoreductase, aldo reductase; n=1; St... 51 4e-05
UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b... 51 4e-05
UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 51 4e-05
UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 51 4e-05
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 51 4e-05
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 51 5e-05
UniRef50_Q2S286 Cluster: Oxidoreductase, aldo/keto reductase fam... 51 5e-05
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 51 5e-05
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 51 5e-05
UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 51 5e-05
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 51 5e-05
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 51 5e-05
UniRef50_A6VX84 Cluster: Aldo/keto reductase; n=4; Gammaproteoba... 50 6e-05
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 50 6e-05
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 50 6e-05
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 310 bits (762), Expect = 3e-83
Identities = 149/330 (45%), Positives = 223/330 (67%), Gaps = 5/330 (1%)
Query: 3 VYKYSFVFVFAAVIHLSPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNEL---KGDEVQK 59
+++ SF+ + A +S + + P+LK+ N +E+P +GT+LG + K +++
Sbjct: 1 MFRASFILLLACCGAMSATIDV-PMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRN 59
Query: 60 SVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVL 119
V AID GYRH DTAAIY+TE +VG AI+ KI EGV+KRED+F+TTKLWNT+HK+E V
Sbjct: 60 VVMQAIDLGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVA 119
Query: 120 PALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSN 179
A++++L LDYVDL+L+HWPIAL+++ S S TDY+ETW+A +++ G TKSIG+SN
Sbjct: 120 VAMKETLNKTGLDYVDLFLMHWPIALNEDYSHSNTDYLETWRATEEMVKLGYTKSIGLSN 179
Query: 180 FNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNR-QPS 238
FN Q+ + E + P LQ+E++ + Q L+ Y K +GI+V+ Y+PFG+L R
Sbjct: 180 FNKLQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPFGSLVKRFGMD 239
Query: 239 APAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTP 298
P P+ DD L ++A+KY+KT QIVLR+LV+ V+PIPK++ R+ ENI I+DF L
Sbjct: 240 LPGPKMDDPVLTSLAKKYEKTPAQIVLRWLVDRKVVPIPKTVSPKRLLENINIFDFKLKE 299
Query: 299 DEIQLLKSFDNGYRTLSPLFWAHSPYFPFE 328
+EI+ + F++ R P FW P++PF+
Sbjct: 300 EEIEKINQFNSNTRYTLPSFWQKHPFYPFD 329
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 284 bits (696), Expect = 3e-75
Identities = 139/316 (43%), Positives = 201/316 (63%), Gaps = 22/316 (6%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+ L++G ++P G+GTW G N DEV+ +V+ AIDAGYRH D A+ Y E ++G+A
Sbjct: 8 ITLSDGNKVPVLGLGTWQGGNDP----DEVENAVKLAIDAGYRHFDCASFYGNEAEIGKA 63
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP----- 142
I++KI +GVVKREDLFV TK+WN K+E V+ A ++SLK L L Y+DLYL+HWP
Sbjct: 64 IQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPI 123
Query: 143 ------IALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTP 196
+ ++ ++ + DY+ETW+ M + + GLT+SIGVSNFN QQL RL + P
Sbjct: 124 LYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKP 183
Query: 197 SVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFG-----NLFNRQPSAPAPRADDQRLVA 251
+ Q+E+++NL Q L ++C ++ I V Y+PFG N+F QP+ +
Sbjct: 184 VMNQIELHINLNQKKLREFCASKSIAVTGYSPFGAPGRNNVF--QPAGADISLQSPVITG 241
Query: 252 IAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGY 311
IA+KY KT QIVLRY++++G IPIPKS + R++ENI I+DF LTP+EI + D G+
Sbjct: 242 IAKKYNKTNAQIVLRYVIDIGAIPIPKSSSEKRIKENIDIFDFKLTPEEIAAIDKLDCGF 301
Query: 312 RTLSPLFWAHSPYFPF 327
RT S + +PF
Sbjct: 302 RTCSAIEHKDCKEYPF 317
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 270 bits (663), Expect = 3e-71
Identities = 147/325 (45%), Positives = 199/325 (61%), Gaps = 24/325 (7%)
Query: 21 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 80
SA P +KLNNG E+P G+GT + KGDE K+V AID G+RHIDTA Y
Sbjct: 2 SARFIPTVKLNNGLEMPAIGLGTSMS------KGDECCKAVMTAIDEGFRHIDTAYNYRN 55
Query: 81 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIH 140
ED VGRAI+ KI EGVV RE+LFVTTKLWNT H + V A KSL++L LDYVDL+LIH
Sbjct: 56 EDVVGRAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIH 115
Query: 141 WPIA-------------LHDNASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 185
P L DN ++ S DYV+TW+AM +L G SIGVSNFN +QL
Sbjct: 116 MPFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQL 175
Query: 186 ERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFG--NLFNRQP-SAPAP 242
ER+ + V P QVE + + Q L+++C + IVV A++PFG +LF + P P P
Sbjct: 176 ERILANCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSPFGRPHLFEKNPKDKPKP 235
Query: 243 RADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQ 302
D+ +V I +K+ K+ Q+VLRYL++ GV+PIPKS +++N++I+DF L+ D++
Sbjct: 236 VLDEPEIVEIGKKFDKSSAQVVLRYLLQNGVVPIPKSTSAQHLKQNLEIFDFELSSDDMA 295
Query: 303 LLKSFDNGYRTLSPLFWAHSPYFPF 327
+L F+ R + Y+PF
Sbjct: 296 ILDGFNTNQRMVRLSLLKEHKYYPF 320
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 265 bits (649), Expect = 1e-69
Identities = 129/304 (42%), Positives = 192/304 (63%), Gaps = 19/304 (6%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P + N+G ++P G+GT+L K EV ++V++AI+ GYRH+DTA Y E ++G
Sbjct: 4 PTVTFNDGYKMPMIGLGTFLS------KPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIG 57
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
AI++KI +G +KRED+FVTTKLW +HK++ V+PA +KSL+NL DY+DL+L+HWP A
Sbjct: 58 SAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAF 117
Query: 146 HDNASI-----------SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV 194
++ S TDY+ETW+ M + QGL +SIG+SNFN +Q+ RL S +
Sbjct: 118 KSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKI 177
Query: 195 TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQ 254
P QVE+ +NL Q L+++CK I V ++P G NR D+ ++ +AQ
Sbjct: 178 KPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLGRPGNRH--GIQNLWDEPQIQKLAQ 235
Query: 255 KYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTL 314
KYKKT I R++ +LGV PIPKS+ K R++EN+ I+DFSLTP+E+ ++ + L
Sbjct: 236 KYKKTPANIACRFIHQLGVTPIPKSVTKSRIKENLDIFDFSLTPEEVSTIEKMGKHNKYL 295
Query: 315 SPLF 318
L+
Sbjct: 296 ILLY 299
Score = 244 bits (597), Expect = 3e-63
Identities = 127/267 (47%), Positives = 168/267 (62%), Gaps = 10/267 (3%)
Query: 69 YRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 128
YRHIDTA +Y E +G AI++KI +G VKREDLFVTTKL HK+ V+PA ++SL +
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 129 LDLDYVDLYLIHWPIALH----DNAS----ISQTDYVETWQAMTDVLNQGLTKSIGVSNF 180
L LDY+DLYLIHWPI + NAS +S TDY+ETW+ M + QGL +SIGVSNF
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVSNF 420
Query: 181 NIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAP 240
N +Q+ RL + P QVE++L L Q AL+++CK I V Y+P G NR
Sbjct: 421 NSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPLGRPGNRYGITN 480
Query: 241 APRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDE 300
A DD + + +KY KT QI R++ +LG IPIPKS+ K R++EN +I+DFSLT +E
Sbjct: 481 A--WDDPIIQELVKKYGKTPAQIACRFVSQLGAIPIPKSVTKSRIKENFEIFDFSLTDEE 538
Query: 301 IQLLKSFDNGYRTLSPLFWAHSPYFPF 327
I ++S G R S Y+PF
Sbjct: 539 INSIQSIATGERVAPMEDAKESKYYPF 565
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 259 bits (635), Expect = 6e-68
Identities = 134/316 (42%), Positives = 194/316 (61%), Gaps = 18/316 (5%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
LAP ++LNNG+E+P G+GTW S + S A+D GYRH+DTA +Y E +
Sbjct: 4 LAPTIRLNNGREMPTLGLGTWKSFES------DAYHSTRHALDVGYRHLDTAFVYENEAE 57
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
VG+AI +KIAEGVV RE++FVTTKL +H V A R SL NL L+YVDLYL+H P+
Sbjct: 58 VGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPV 117
Query: 144 A--------LHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVT 195
+H ++ DY++TW+ M +++ GLT+SIG+SNFN Q ER+ + +
Sbjct: 118 GQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIR 177
Query: 196 PSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAP-APRADDQRLVAIAQ 254
P V QVE + QQ L ++ K G+V+ AY P L QP+ P D+ +A+
Sbjct: 178 PVVNQVECHPGFQQRQLREHAKRHGLVICAYCP---LARPQPARQWPPFLYDEHAQNLAK 234
Query: 255 KYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTL 314
KY +T QI LRYLV+LGV+P+PKS +K R+EEN +++DF L+PD++ ++ + G RT+
Sbjct: 235 KYGRTTAQICLRYLVQLGVVPLPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQRTV 294
Query: 315 SPLFWAHSPYFPFESK 330
+ Y+PF +
Sbjct: 295 PFSGMSGHKYYPFNDE 310
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 259 bits (634), Expect = 8e-68
Identities = 133/300 (44%), Positives = 192/300 (64%), Gaps = 6/300 (2%)
Query: 9 VFVFAAVIHLSPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAG 68
V ++A V +S G AP+ +LN+G IP +GT+ ++ +V+++V WAI AG
Sbjct: 8 VALWALVNAISGEPGKAPLKQLNDGNAIPSLALGTF---GFGDIP--KVRQAVLWAIQAG 62
Query: 69 YRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKN 128
YRHIDTAA+Y E++VG+ I I +G+VKRE+LFVTTKLWN H + V+PALR+SL
Sbjct: 63 YRHIDTAALYGNEEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTK 122
Query: 129 LDLDYVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERL 188
L L YVDLYLIH P A ++N D + TW M + GL KSIGVSNF+ L+RL
Sbjct: 123 LGLSYVDLYLIHSPEATNENGDPVDIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRL 182
Query: 189 KSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQR 248
+ P+V Q+E++ + Q L+ +GI V+AY+PFG +R S P +D+
Sbjct: 183 IAGSNTVPAVNQIEVHPSKTQEKLVADSHERGIEVMAYSPFGFYVSR-GSHNNPVKNDRT 241
Query: 249 LVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
+ IA+KY KTV Q+++RYL+E +IPIPKS ++ R+ ENI ++DF L+P++I + D
Sbjct: 242 VADIARKYNKTVNQVLVRYLLERSLIPIPKSTNQQRIRENIDVFDFQLSPEDINAIGKLD 301
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 244 bits (597), Expect = 3e-63
Identities = 136/319 (42%), Positives = 193/319 (60%), Gaps = 24/319 (7%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P ++ +NG EIP G GT+L KG V+ V+ AID GYRHIDTA +Y E ++G
Sbjct: 6 PTVRFSNGYEIPVLGYGTYLAQ-----KGQCVEL-VKKAIDLGYRHIDTAFLYENEVEIG 59
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
+AI+ KIAEGV++RED+FVTTKLWNT H + V A R+S LD+ Y+DL+L+H P+ +
Sbjct: 60 QAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGV 119
Query: 146 H---------------DNASISQTDYVETWQAMTDVLNQ-GLTKSIGVSNFNIQQLERLK 189
N S DYVETW+AM ++ G +SIG+SNFN +Q+ER+
Sbjct: 120 QFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERIL 179
Query: 190 SEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRL 249
V P QVE N Q L+ +C+A+GI V AY P G +R + DD ++
Sbjct: 180 QIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGPMGRP-HRTTNGNRNALDDPKV 238
Query: 250 VAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDN 309
+ I +KY KT Q++LRYL+++G IPIP S +++R+ +NI + DF LT +EI+ L SF +
Sbjct: 239 LEIGRKYGKTGGQVILRYLIDIGTIPIPYSTNEERMRQNIDVCDFKLTGEEIEYLASFHS 298
Query: 310 GYRTLSPLFWAHSPYFPFE 328
RT+ L Y+PF+
Sbjct: 299 A-RTIPFLPLKSHKYYPFD 316
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 244 bits (597), Expect = 3e-63
Identities = 127/322 (39%), Positives = 202/322 (62%), Gaps = 22/322 (6%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
+A L+LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y E +
Sbjct: 1 MASHLELNNGTKMPTLGLGTWKSPPG------QVTEAVKVAIDLGYRHIDCAQVYQNEKE 54
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHW-- 141
VG A+++K+ E VVKR+DLF+ +KLW T H K V A +K+L +L LDY+DLYLIHW
Sbjct: 55 VGVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPT 114
Query: 142 ---------PIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEG 192
P+ N S TD+V+TW AM ++++GL K+IGVSNFN Q+ER+ ++
Sbjct: 115 GFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKP 174
Query: 193 GV--TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN--RQPSAPAPRADDQR 248
G+ P+V Q+E + L Q L++YC ++GIVV AY+P G+ +P P+ +D R
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPS-LLEDPR 233
Query: 249 LVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
+ AIA KY KT Q+++R+ ++ ++ IPKS+ R+ EN++++DF ++ +++ L S++
Sbjct: 234 IKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYN 293
Query: 309 NGYRTLSPLFWAHSPYFPFESK 330
+R + + A +PF ++
Sbjct: 294 RNWRVCALMSCAKHKDYPFHAE 315
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 241 bits (589), Expect = 2e-62
Identities = 126/321 (39%), Positives = 185/321 (57%), Gaps = 19/321 (5%)
Query: 21 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 80
+ + P NG IP FG+GTW N G +V ++V+ AID GYRHID A +Y
Sbjct: 2 TCNVVPNAIFKNGNSIPMFGLGTW-----NSPPG-QVAQAVKDAIDVGYRHIDCAHVYQN 55
Query: 81 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIH 140
E +VG I KIAEGVVKREDLFVT+KLWNT H+ + V A + +L+NL LDY+DLYLIH
Sbjct: 56 EHEVGEGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIH 115
Query: 141 WPIALHDNASI------------SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERL 188
WP+ + + S DYV+TW M +++ GL ++IGVSNFN +Q++R+
Sbjct: 116 WPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRV 175
Query: 189 KSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAP-RADDQ 247
+ P+ Q+E + L Q + +C +GI+V AY+P G+ A P DD
Sbjct: 176 LDVARIPPATNQIECHPYLHQSKITTFCAEKGIIVTAYSPLGSPARPWVKADDPVLMDDA 235
Query: 248 RLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSF 307
+ +A+K+ K+ QI++RY ++LG + IPKS+ K+R+ N ++ F L D+++ L
Sbjct: 236 TVGQLAKKHGKSAAQILIRYQIQLGHVVIPKSVTKERIASNFDVFSFQLDEDDMKQLAGL 295
Query: 308 DNGYRTLSPLFWAHSPYFPFE 328
+ R P+ PFE
Sbjct: 296 ERNGRICPESSAFGHPHHPFE 316
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 239 bits (585), Expect = 7e-62
Identities = 137/311 (44%), Positives = 183/311 (58%), Gaps = 37/311 (11%)
Query: 25 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQV 84
AP++KLNNG E+P G+GTWL S E +G E K+ AIDAGYRHIDTA Y E +V
Sbjct: 5 APMVKLNNGLEMPVLGLGTWL---SKEGEGVEAIKA---AIDAGYRHIDTAYFYQNEKEV 58
Query: 85 GRAIKKKIAEGVVKREDLFVTTKL--WNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP 142
G AI+ KI EGVV REDLFVTTK W+T K+L D D
Sbjct: 59 GEAIRAKIEEGVVCREDLFVTTKFIDWDT------------KNLMPYDAD---------- 96
Query: 143 IALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVE 202
S DY++TW+AM +L G KSIGVSNFN +Q+ RL +E + P QVE
Sbjct: 97 ----GKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQVE 152
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFG--NLFNRQP-SAPAPRADDQRLVAIAQKYKKT 259
N +L Q L ++CK I + AY+P G N + + P + P P DD +++ I +KY KT
Sbjct: 153 CNPSLNQRKLTEFCKNLDITLTAYSPLGRPNYYEKDPDNMPKPALDDPKVIEIGKKYNKT 212
Query: 260 VPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFW 319
Q++LRYLV++G IPIPKS + +R+ +NI I+DF LT +EI+++ F G RT+
Sbjct: 213 SGQVILRYLVDIGTIPIPKSSNSERIRQNIDIFDFKLTEEEIKIMDGFHTGQRTVPFNLC 272
Query: 320 AHSPYFPFESK 330
YFPF ++
Sbjct: 273 TSHKYFPFNAE 283
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 238 bits (583), Expect = 1e-61
Identities = 132/316 (41%), Positives = 191/316 (60%), Gaps = 20/316 (6%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
++LN+G IP G GT+ LK ++ S + AID G+ HID + +Y E+++G+A
Sbjct: 8 IELNDGHSIPVLGFGTY--ATEEHLKKKSME-STKIAIDVGFCHIDCSHLYQNEEEIGQA 64
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL-- 145
I KI +G VKRED+F T+KLW+T+H+ E V P+L SL+ L+LDYVDLYLIH+P++L
Sbjct: 65 ILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKP 124
Query: 146 ---------HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV-- 194
H N D +TW+AM + GL KSIGVSNFN +QLE + ++ G+
Sbjct: 125 GNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 195 TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFG-NLFNRQPSAPAP-RADDQRLVAI 252
P QVE +L L Q LL YCK IV+VAY G + + P DD L A+
Sbjct: 185 KPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPVLCAM 244
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
A+KYK+T I LRY ++ G++ + KS +++R+ EN+Q++DF L D++++L D R
Sbjct: 245 AKKYKRTPALIALRYQLDRGIVALAKSFNEERIRENMQVFDFQLASDDMKILDGLDRNLR 304
Query: 313 TL-SPLFWAHSPYFPF 327
+ +F AH P FPF
Sbjct: 305 YFPADMFKAH-PNFPF 319
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 236 bits (578), Expect = 5e-61
Identities = 126/315 (40%), Positives = 192/315 (60%), Gaps = 18/315 (5%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+KLN+G IP G GT+ E+ + ++ A+D GYRH+DTA Y E+++G+A
Sbjct: 8 VKLNDGHLIPALGFGTY---KPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQA 64
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH- 146
I+ KI GVVKREDLF+TTKLW T + E V PAL KSLK L LDYVDLY++H+P+ +
Sbjct: 65 IQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKS 124
Query: 147 -DN---------ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV-- 194
DN + + D+ +TW+ + + + GL KSIGVSNFN +QLER+ ++ G+
Sbjct: 125 GDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKY 184
Query: 195 TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFG-NLFNRQPSAPAP-RADDQRLVAI 252
P QVE +L L Q LLDYC+++ IV+VAY G + +P +D L +
Sbjct: 185 KPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDV 244
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
A+K K++ I LRYL++ G++P+ +S ++ + EN+Q++ F L+P++++ L + +R
Sbjct: 245 AKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFR 304
Query: 313 TLSPLFWAHSPYFPF 327
L F P +PF
Sbjct: 305 YLPAEFLVDHPEYPF 319
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 235 bits (575), Expect = 1e-60
Identities = 122/293 (41%), Positives = 177/293 (60%), Gaps = 11/293 (3%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG +IP G+GTW+ N EV K+VE AI GYRHID A Y E +VG IK
Sbjct: 7 LNNGYKIPKLGLGTWMSANG------EVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIK 60
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
IA+G VKRE+LFVTTKLW+T+ KE V PA +SLK L L+Y+DLY+IH P+
Sbjct: 61 SAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTADKKT 120
Query: 150 SISQTDYV---ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 206
+ + ETW+ M ++ +GL KSIGVSNFNI++LE L + + P+V Q E ++
Sbjct: 121 GEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHIY 180
Query: 207 LQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLR 266
Q+P L +CK I + Y P GN PAP +++ + AIA+K+ K QI ++
Sbjct: 181 YQRPKLHQFCKKHNIHITGYCPLGNP-GISSGVPAP-FENEVVKAIAKKHNKKAAQICIK 238
Query: 267 YLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFW 319
+ + G IPKS+H++R++EN +++DF L ++++ L+ D + F+
Sbjct: 239 FSIASGHSVIPKSVHEERIKENGEVFDFELDEEDMEKLRGLDKNIKVCDMSFY 291
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 234 bits (573), Expect = 2e-60
Identities = 127/326 (38%), Positives = 199/326 (61%), Gaps = 30/326 (9%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
+A + L G ++P G+GTW + +V+++V+ AIDAGYRHID A +Y E +
Sbjct: 1 MAAFVTLLTGAKMPIVGLGTWKSPPA------KVREAVKVAIDAGYRHIDCAYVYQNESE 54
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP- 142
VG AI++KI E VKREDLF+ +KLW+T +K V A + +L +L LDY+DLYLIHWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQ 114
Query: 143 --------IALHDNASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEG 192
+ D SI S+ +++ W+AM ++++QGL K++GVSNFN Q+ERL ++
Sbjct: 115 GFQSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKP 174
Query: 193 GV--TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLV 250
G+ P QVE + L Q L YC ++GI + AY+P G+ P P+ + +D L+
Sbjct: 175 GLKHKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSPLGS-----PDRPSAKPEDPLLL 229
Query: 251 ------AIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
IA K+KKT Q+++R+ +E V+ IPKS+ R++ENIQ++DF L+ +++ +
Sbjct: 230 EIPKIKEIAAKHKKTAAQVLIRFHIERNVVVIPKSVTPSRIQENIQVFDFQLSEEDMAAI 289
Query: 305 KSFDNGYRTLSPLFWAHSPYFPFESK 330
SF+ +R +H+ FPF ++
Sbjct: 290 LSFNRNWRACGLFAASHNEDFPFHAE 315
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 234 bits (573), Expect = 2e-60
Identities = 131/322 (40%), Positives = 193/322 (59%), Gaps = 25/322 (7%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P L+NGK +P G+GTW + V ++V+ AID GYRH D A IY E QVG
Sbjct: 4 PNFLLSNGKNMPMLGLGTWRSPP------EVVTQAVKDAIDIGYRHFDCAHIYGNEAQVG 57
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
A+++K+ EGVV R++LF+T+KLWNT+HK + V PA S++NL + Y++LYL+HWP+A
Sbjct: 58 AALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAY 117
Query: 146 ---HDN----------ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEG 192
DN A+ DYV+TW+AM +++++GL ++IGVSNFN QQ+ RL S
Sbjct: 118 KSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVA 177
Query: 193 GVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN--RQPSAPAPRADDQRLV 250
+ P VLQ+E + L Q L+ C I V AY+ G+ +P A P ++
Sbjct: 178 KLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGA-YPLLQHPTIL 236
Query: 251 AIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENI-QIYDFSLTPDEIQLLKSFD- 308
AIA+KY++T Q++LR+ + G+I IP+S+ K + +N +I+DF L D+IQ + D
Sbjct: 237 AIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDC 296
Query: 309 NGYRTLSPLFWAHSPYFPFESK 330
NG + H P+ PFE K
Sbjct: 297 NGRFMTMKAAYGH-PHHPFEPK 317
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 234 bits (572), Expect = 3e-60
Identities = 124/322 (38%), Positives = 202/322 (62%), Gaps = 22/322 (6%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
+A L LNNG ++P G+GTW +V ++V+ AID GYRHID A +Y E++
Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENE 54
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP- 142
VG AI++K+ E VVKRE+LF+ +KLW T H+K V A +K+L +L LDY+DLYLIHWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 143 --------IALHDNASI--SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEG 192
L ++ ++ S T+ ++TW AM +++++GL K+IG+SNFN Q+E + ++
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 193 GV--TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN--RQPSAPAPRADDQR 248
G+ P+V Q+E + L Q L+ YC+++GIVV AY+P G+ +P P+ +D R
Sbjct: 175 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS-LLEDPR 233
Query: 249 LVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
+ AIA K+ KT Q+++R+ ++ ++ IPKS+ +R+ EN +++DF L+ ++ L S++
Sbjct: 234 IKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYN 293
Query: 309 NGYRTLSPLFWAHSPYFPFESK 330
+R + L +PF +
Sbjct: 294 RNWRVCALLSCTSHKDYPFHEE 315
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 232 bits (568), Expect = 8e-60
Identities = 121/307 (39%), Positives = 196/307 (63%), Gaps = 21/307 (6%)
Query: 25 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQV 84
A + L+ G+++P G+GTW + + +V+ +V++A+ GYRHID AAIY E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 85 GRAIKKKIAEG-VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
G A+K+ + G V RE+LFVT+KLWNT H E V PALRK+L +L L+Y+DLYL+HWP
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 144 ALH--DNA---------SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEG 192
A DN T Y ETW+A+ ++ +GL +++G+SNFN +Q++ + S
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 193 GVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN--RQPSAPAPRADDQRLV 250
V P+VLQVE + L Q L+ +C+A+G+ V AY+P G+ R P P ++ ++
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPV-LLEEPVVL 235
Query: 251 AIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
A+A+KY ++ QI+LR+ V+ VI IPKS+ R+ +NI+++DF+ +P+E++ L + +
Sbjct: 236 ALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKN 295
Query: 311 YRTLSPL 317
+R + P+
Sbjct: 296 WRYIVPM 302
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 232 bits (567), Expect = 1e-59
Identities = 132/319 (41%), Positives = 188/319 (58%), Gaps = 19/319 (5%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+ L++G IP G+GT+ S KG SV+ AID GYRHID A IY E +VG A
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTP-KG-ACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
I++KIAEG V+RED+F KLW TNH E V P L ++L+ L LDYVDLY+I P+A
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 148 NASI-----------SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV-- 194
I +++ TW+AM + GL KS+GVSNFN +QLE + ++ G+
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 195 TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNR---QPSAPAPRADDQRLVA 251
P QVE + QP LL +C+ IV+ AY+P G N S+P P D L +
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSP-PLLKDALLNS 246
Query: 252 IAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGY 311
+ ++Y KT QIVLR+ ++ GV+ IPKS + +R++EN QI+DFSLT +E++ +++ +
Sbjct: 247 LGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNV 306
Query: 312 RTLSPLFWAHSPYFPFESK 330
R + L W P +PF +
Sbjct: 307 RFVELLMWRDHPEYPFHDE 325
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 230 bits (563), Expect = 3e-59
Identities = 125/306 (40%), Positives = 178/306 (58%), Gaps = 25/306 (8%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
+ P KL++G +IP G GTW + V K+VE A+DAGYRHID AA+Y E +
Sbjct: 1 MEPSFKLSSGHKIPLVGFGTWKAETTL------VGKAVEVALDAGYRHIDCAAVYLNEKE 54
Query: 84 VGRAIKKKIA-EGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP 142
VG A KK E VKRED+F+T+KLWNT HKKE V PAL ++L +L L Y+DLYL+HWP
Sbjct: 55 VGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWP 114
Query: 143 IALHDNASISQT-----DYV---ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV 194
+A ++ QT ++V ETW+ M +++ GL KSIG+SNFN+Q L + S +
Sbjct: 115 VAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARI 174
Query: 195 TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQ 254
P+ QVE++ L QP L +C I + AY+P GN D++ + AIA+
Sbjct: 175 KPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLGN---------GAFVDNEEVGAIAK 225
Query: 255 KYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTL 314
KY KT+P ++ ++ ++ IPKS RV EN +++F + ++ L D RT
Sbjct: 226 KYNKTIPNVLCKWAIQKNFSVIPKSSTPSRVAENFDLFNFEIEEADMLFLDKMDKNLRTC 285
Query: 315 SPL-FW 319
P FW
Sbjct: 286 DPAKFW 291
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 227 bits (554), Expect = 4e-58
Identities = 120/309 (38%), Positives = 186/309 (60%), Gaps = 17/309 (5%)
Query: 37 PGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGV 96
PG GT GT + + D+V+ + + A+D GYRH+D A +YS+E VG+A ++K A+G
Sbjct: 38 PGHCAGTKHGTEKSFI--DDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGT 95
Query: 97 VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL----------- 145
+KREDLF T+KLWNT H+ V PAL K+L L +DYVDLYLIH P++
Sbjct: 96 LKREDLFYTSKLWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNE 155
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQVEI 203
+ Q D ++TWQA+ + + GL KSIGVSNFN +QLE + ++ G+ P Q+E
Sbjct: 156 DGTCAFDQPDLLQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIEC 215
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNL-FNRQPSAPAP-RADDQRLVAIAQKYKKTVP 261
+ L Q +L++CK++ IVVVAY G+ + P +D L++I QKY K+
Sbjct: 216 HPYLNQKQMLEFCKSKDIVVVAYGVLGSPGAGKWVDQSCPILLEDPVLISIGQKYSKSPA 275
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFWAH 321
Q+ +RY+++ G + I KS + DR+++N++++DF L+ +E+ + + R S W
Sbjct: 276 QVSMRYMIQRGCVAIAKSFNPDRMKQNLEVFDFQLSQEEMAAIDGLNKNMRYWSFSEWEK 335
Query: 322 SPYFPFESK 330
P +PF S+
Sbjct: 336 HPQYPFHSQ 344
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 223 bits (546), Expect = 4e-57
Identities = 117/291 (40%), Positives = 174/291 (59%), Gaps = 20/291 (6%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L +G +P G+GTW +LK DEV ++ A+DAGYRH D A IY E +VG A++
Sbjct: 7 LPSGHAMPLVGLGTW------KLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALR 60
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD-- 147
+ + +KRED+F+TTK+WNT H KE V +SL +L LDY+DLY++HWP+ +
Sbjct: 61 EAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLG 120
Query: 148 -----------NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTP 196
+ S Y+ETW AM D++ G KS+G+SNFN +QL+ + V P
Sbjct: 121 PTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPP 180
Query: 197 SVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRA-DDQRLVAIAQK 255
SVLQVE + L Q LL++C+ + +VV AY+P G + P DD L+ IAQ+
Sbjct: 181 SVLQVESHPFLPQVELLNFCRERSVVVSAYSPLGCGDRAWKLSGEPSIFDDPGLLKIAQR 240
Query: 256 YKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
+K++ Q+ +R+ V+ G+ IPKS ++ENI ++DF L+ D++ LL S
Sbjct: 241 LRKSIAQVAIRFQVQRGIPVIPKSATPSHIQENINVFDFELSEDDMALLSS 291
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 221 bits (541), Expect = 2e-56
Identities = 120/318 (37%), Positives = 187/318 (58%), Gaps = 18/318 (5%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
++LN+G ++P G GT+ + +E K AID GYRHID A +Y E++VGRA
Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKV---AIDVGYRHIDCAFLYGNEEEVGRA 65
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
I+ KIA+G VKRED+F T KLW+T+H E V PAL KSLK+L LDY+DL++IH P+
Sbjct: 66 IRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKP 125
Query: 148 NASI-----------SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV-- 194
+ TD +TW+A+ + GL +SIGVSNFN +QLE + + G+
Sbjct: 126 GDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKY 185
Query: 195 TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN-RQPSAPAP-RADDQRLVAI 252
P QVE ++ L Q LL++CK++ IV+V Y+ G+ + R A P +D L I
Sbjct: 186 KPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDPALTEI 245
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
A+K+ +T Q+ +RY ++ GV+ + KS R+++N Q++DF L ++++ + + R
Sbjct: 246 AKKHNRTPAQVAMRYHLQRGVVVLAKSFTPARIQQNFQVFDFQLDAEDMRSIDGLNRNMR 305
Query: 313 TLSPLFWAHSPYFPFESK 330
+ W+ P +P+ +
Sbjct: 306 YIDTSRWSDHPKYPYSEE 323
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 221 bits (541), Expect = 2e-56
Identities = 124/318 (38%), Positives = 186/318 (58%), Gaps = 22/318 (6%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P L++G+ +P G+GTW + V ++V+ AID GYRH D A IY E VG
Sbjct: 4 PSFLLSSGRNMPMVGLGTWRSPP------EVVAQAVKDAIDIGYRHFDCAHIYGNELHVG 57
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
AI++KI EG+V R++LF+T+KLWNT HK E V A SL+NL +DY+DLYL+HWP+A
Sbjct: 58 VAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAY 117
Query: 146 H--DN----------ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGG 193
DN A DY++TW+AM D+++ GL +IGVSNFN +Q+ RL
Sbjct: 118 KSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAK 177
Query: 194 VTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN-RQPSAPAPRADDQRLVAI 252
+ P +LQ+E + L+Q +L+ C I V AY+ G+ + P + +V++
Sbjct: 178 LKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYSSLGSGHTPYEKPGSYPLLQNPIIVSV 237
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENI-QIYDFSLTPDEIQLLKSFD-NG 310
A+KY +T Q++LRY + G+I IP+S+ K + +N +I+DF L D+++ + D NG
Sbjct: 238 AEKYGRTPAQVLLRYQTQSGIIVIPRSVSKQHMHDNFKRIWDFQLAIDDVKAIDGLDCNG 297
Query: 311 YRTLSPLFWAHSPYFPFE 328
+ H P+ PFE
Sbjct: 298 RFMTMKAAYGH-PHHPFE 314
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 221 bits (540), Expect = 2e-56
Identities = 125/309 (40%), Positives = 178/309 (57%), Gaps = 24/309 (7%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
L L N + +P G GTW EL VE AI AGYRHID A IY E +VG
Sbjct: 4 LTLRNKQTLPLLGYGTW------ELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEG 57
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH- 146
I++ I +GVVKREDLFVT+KLWNT+H + V A RK+L +L LDY+DLYLIHW +A
Sbjct: 58 IRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFEH 117
Query: 147 -------DNASISQTDYV---ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTP 196
D+ +++ ++ ETWQAM +++ QGL KS+GV+NF L L S + P
Sbjct: 118 GDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIKP 177
Query: 197 SVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKY 256
+V Q+E++ L Q L+ +C +Q I V AY+PFG S AP D + +A+
Sbjct: 178 AVHQIELHPYLAQNDLVAFCYSQNIAVTAYSPFG-------STEAPVLTDPTVKEVAKGL 230
Query: 257 KKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSP 316
KT Q++LR+ V+ IP+S + R++EN +I F L+ + + L + + R ++P
Sbjct: 231 GKTPAQVLLRWAVQRNTSVIPRSSNATRIKENFEIATFELSNEHMAALNTLNRNKRFVNP 290
Query: 317 LFWAHSPYF 325
+ W PYF
Sbjct: 291 IEWWGFPYF 299
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 217 bits (531), Expect = 2e-55
Identities = 116/312 (37%), Positives = 185/312 (59%), Gaps = 17/312 (5%)
Query: 27 VLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGR 86
+L LNNG IP G+GT+ ++ G + +++ A++ GYR IDTA +Y+ E VG+
Sbjct: 1 MLALNNGHSIPPIGLGTY------KITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQ 54
Query: 87 AIKKKIAEGV-VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
A+++ ++G + RED+F+ +KL T H+ EAV R SL+ L LDYVDLYL+H P+A
Sbjct: 55 ALREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAA 114
Query: 146 HDNASISQTDYV-------ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
D+ + + ETW+A+ + +GL +SIGVSNFN +QL + + G + P V
Sbjct: 115 RDSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVV 174
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKK 258
QVE ++ Q L +C +GI+++AY+P G +P D L +A+KY +
Sbjct: 175 NQVECSIGFHQVKLRKFCNREGILIMAYSPLG---KPKPGKKHVFLDSSDLNKMAEKYGR 231
Query: 259 TVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLF 318
+ QI LR+L+E+G IPIPKS DR++EN+ + F L ++Q L+SF R+++ +
Sbjct: 232 SPAQISLRFLIEIGTIPIPKSSKTDRMKENLDVLSFKLEETDVQALESFVKQQRSMTLDW 291
Query: 319 WAHSPYFPFESK 330
S ++PF +
Sbjct: 292 LKSSKHYPFNDQ 303
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 217 bits (530), Expect = 3e-55
Identities = 123/316 (38%), Positives = 179/316 (56%), Gaps = 24/316 (7%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
LKLN+G IP G+GTW + K EV +++ A+ AGYRHID A +Y + +VG A
Sbjct: 5 LKLNSGYSIPAIGLGTW------QSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEA 58
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
+K+ + EG VKRE+LF+T+K+WNT H + + L +L L YVDL LIHWP +
Sbjct: 59 LKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAE 118
Query: 148 NASI-----------SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTP 196
A + S DY+ETW+A G +SIG+SNF Q++R+ V P
Sbjct: 119 GAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKP 178
Query: 197 SVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGN---LFNRQPSAPAPRADDQRLVAIA 253
+ LQVE++ Q L ++CK +GIVVV Y+P GN F R+ P ++ + IA
Sbjct: 179 ACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNEV-VAGIA 237
Query: 254 QKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR- 312
+ + KT QI+LR+ V+ G+ IPKS+ R+ EN+ ++DF LT +EI + + +R
Sbjct: 238 KAHGKTPAQIILRWFVDSGLSAIPKSVTPQRISENLAVFDFQLTAEEISKIDGINKNWRI 297
Query: 313 -TLSPLFWAHSPYFPF 327
LS H P+ PF
Sbjct: 298 VDLSQRDGDH-PHCPF 312
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 216 bits (528), Expect = 6e-55
Identities = 121/316 (38%), Positives = 178/316 (56%), Gaps = 28/316 (8%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KLN+G +IP G+GT+ N E+ GD + A+ GYRHID AA Y E +G ++
Sbjct: 18 KLNDGNQIPSIGLGTYYSENPGEV-GDAINN----ALKNGYRHIDGAAFYGNEKVIGNSL 72
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD- 147
K+ EG +KRED+F T+KLWN+ H V+ K++++L + Y+DLYLIHWPIA +
Sbjct: 73 KEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENS 132
Query: 148 ---------------NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEG 192
N I+ ETWQ M ++ GL KSIGVSNFN+Q L L +
Sbjct: 133 NPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYA 192
Query: 193 GVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAI 252
+ P V QVEI+ L Q L +YC I +VAY+P G ++ L +I
Sbjct: 193 KIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLG-------QGKCDFFSNKILKSI 245
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
A KYKK+V ++ ++L + G+ IPKS + R+ EN I+DF L+ D+I+ + S + R
Sbjct: 246 AGKYKKSVANVIFKWLNQRGIAAIPKSGNHSRIIENFNIFDFQLSNDDIEKINSLNANIR 305
Query: 313 TLSPLFWAHSPYFPFE 328
T SP+ + +P++ F+
Sbjct: 306 TCSPITFFGTPFYLFD 321
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 215 bits (525), Expect = 1e-54
Identities = 118/318 (37%), Positives = 186/318 (58%), Gaps = 22/318 (6%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L G+++P G GTW ++K +EV + +E AID GYRHID A++Y E VG IK
Sbjct: 10 LPGGRKLPLLGFGTW------QIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIK 63
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA----- 144
KI +G +KREDLFVT+KLW T+ V P+ R+SL +L L Y+DL+LIH P +
Sbjct: 64 AKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGK 123
Query: 145 ----LHDNASI---SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTP- 196
+ DN DYV+TW+ M ++++GL ++IGVSNF + Q++R+ P
Sbjct: 124 GPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPKYPI 183
Query: 197 SVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGN---LFNRQPSAPAPRADDQRLVAIA 253
+ +QVE + L Q L+++CK QGI V AY+P G+ + ++ + +D + AIA
Sbjct: 184 ANVQVECHPFLAQNELIEFCKKQGITVTAYSPLGSPERVLQKRATTDPLLMEDPVVCAIA 243
Query: 254 QKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
+K + Q+++RY ++ GV +PKS+ R+++N + +F L+ +E Q L + + YR
Sbjct: 244 KKKGVSPAQVLIRYQLQRGVAVLPKSVMPSRIQQNFEALNFELSKEEFQALVNLNKNYRL 303
Query: 314 LSPLFWAHSPYFPFESKN 331
L+ + Y+PF N
Sbjct: 304 LNFAPMKNMKYYPFNDNN 321
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 215 bits (524), Expect = 2e-54
Identities = 120/301 (39%), Positives = 178/301 (59%), Gaps = 15/301 (4%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P + LN+G IP G+GT + ++ + V +E A++ GYRH D+AA Y E +G
Sbjct: 12 PTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNEAIIG 71
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
+ +++ I+EG VKRE+LF+TTKL ++++ V L+KSL NL L YVDLYL+H+P +
Sbjct: 72 QVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHYPCGI 131
Query: 146 --HDNASIS--------QTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVT 195
D +S TD W+AM L G TK+IG+SNFN Q++R+ V
Sbjct: 132 LDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIKGCQVR 191
Query: 196 PSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN--RQPSAPAP---RADDQRLV 250
P+VLQVE+++ +QQ AL +C IVV A+ P G F R+ S P +D +++
Sbjct: 192 PAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGPFRLIRKASRPGEVKLLLEDPQVL 251
Query: 251 AIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
+A + KT Q++LRYL ++ VIPIPKS + R+ +N QI+DF LT E+ L D G
Sbjct: 252 DVATAHHKTPAQVLLRYLHQINVIPIPKSANPTRLFQNTQIFDFELTSAEMSRLAGLDRG 311
Query: 311 Y 311
+
Sbjct: 312 H 312
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 214 bits (523), Expect = 2e-54
Identities = 117/301 (38%), Positives = 178/301 (59%), Gaps = 31/301 (10%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L+NG ++P GIGTW + NE+ +++WA++AGYRH+DTA Y E VG+ I
Sbjct: 10 LSNGVQVPQLGIGTWEAKDGNEVV------NIKWAVNAGYRHVDTAHYYKNEKGVGQGI- 62
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
+E V R D+FVTTKLWN +H E+ L A +S + L ++YVDLYLIHWP N
Sbjct: 63 ---SECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP---GPNR 116
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
S Y+ETW+A + ++IGVSNF L+ L + V P V QVE++ + QQ
Sbjct: 117 S-----YIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEMHPHFQQ 171
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
AL YC + I V A+ P G + +LV +A+K+K++ Q+++R+L+
Sbjct: 172 KALRAYCAEKNIAVTAWRPLGK---------GALLTEPQLVELAEKHKRSAAQVIIRWLI 222
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFWAHSPYFPFES 329
+LGVI IPKS H++R+++N ++DF L+P++++ ++S D R S + +FP E
Sbjct: 223 QLGVIAIPKSSHEERIKQNFDVFDFELSPEDMRRIESMDRNSRIGS----SPETFFPTER 278
Query: 330 K 330
K
Sbjct: 279 K 279
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 212 bits (518), Expect = 9e-54
Identities = 118/326 (36%), Positives = 190/326 (58%), Gaps = 29/326 (8%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
L NNG+++P GIGTW ++ +E++ +++ A++AGYRHIDTA +Y E +GR
Sbjct: 7 LTFNNGEKMPVIGIGTWQASD------EEIETAIDAALEAGYRHIDTAPVYGNEKAIGRV 60
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
+K+ + G VKRE+LF+ TK+ +++ V P ++KSL++L LDYVDLYL+H P ++
Sbjct: 61 LKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTINI 120
Query: 148 NASIS-------------QTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV 194
N S T++ W AM ++ +GLTKSIGVSNF+ Q+ RL +
Sbjct: 121 NEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKI 180
Query: 195 TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPA-------PRADDQ 247
P+ Q+E ++ LQQ L+D+CK++ I V AY+P G+ + +A A D
Sbjct: 181 RPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIP 240
Query: 248 RLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSF 307
+ IA + KT Q++LR++++ GV IPKS + R+++N+ ++DF LT +E+ L S
Sbjct: 241 EVKEIAASHGKTPAQVLLRWIIDTGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSL 300
Query: 308 DNGYRTLSPLFW---AHSPYFPFESK 330
D R F+ P F F+++
Sbjct: 301 DQNIRICDFAFFHGVERHPEFTFKNQ 326
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 211 bits (516), Expect = 2e-53
Identities = 124/322 (38%), Positives = 185/322 (57%), Gaps = 25/322 (7%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P+ L+NG +P G+GTW ++ G+E + + A+ AGYRHIDTA +Y E Q+G
Sbjct: 6 PIFTLSNGVLMPSIGLGTW------QMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIG 59
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
A+ + AEG++KRED+F+TTK + + V ALR SLK L LDYVDLYL H P +
Sbjct: 60 DALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPAST 119
Query: 146 HDNASI-SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEIN 204
D+ S S + W+ V GLTK+IGVSNFN Q+ R+ + V Q+E++
Sbjct: 120 KDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHASQLELH 179
Query: 205 LNLQQPALLDYCKAQGIVVVAYTPFGNL-------FNRQPSAPAPR-----ADDQRLVAI 252
L L Q A + CK I++ AY G+ N +P + + +D+ + A+
Sbjct: 180 LYLPQKAHRELCKKHNILITAYATLGSPGRMSVVGSNGRPLFESTQNSENEMNDKHVKAL 239
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
AQKY KT QI+LR VE+G+I IPK+ + +R++ENI I+DF+++ E+ LL++ + +
Sbjct: 240 AQKYSKTPAQILLRATVEMGIIVIPKTTNPERMKENINIFDFNISNAEVNLLEAHERTKQ 299
Query: 313 TLSPLFW----AHSPYFPFESK 330
LFW A P PF ++
Sbjct: 300 --ERLFWWPNVADHPEDPFATQ 319
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 210 bits (513), Expect = 4e-53
Identities = 113/307 (36%), Positives = 178/307 (57%), Gaps = 22/307 (7%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
LK +G IP G+GTW + ++V+K+V+ A++ GY+HID AA Y ED VG A
Sbjct: 4 LKFRDGDSIPSIGLGTW------KSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEA 57
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL-- 145
K+ G VKRED+FVT+KLWN HKKE V+PAL+K+LK+L+LDY+DLYL+HWP+A
Sbjct: 58 FKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKP 117
Query: 146 ---------HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTP 196
D S+ + ET AM + QGL K +GVSNF+ ++LE LK + P
Sbjct: 118 SVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMP 177
Query: 197 SVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRA----DDQRLVAI 252
+ QVE++ L Q L YC +GI++ Y+P G+ +R A +D + +
Sbjct: 178 EMNQVELHPYLPQNDLYSYCSKEGILLTGYSPLGS-GDRSEGMKADDEPSLFEDDTIKKV 236
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
A++ + Q ++ + + G IPKS ++ R++EN++ + L+ ++++ + + YR
Sbjct: 237 AERNNISKGQTLIAWAKQRGTAVIPKSTNEGRIKENLESDNIELSKEDLEDIANIGKNYR 296
Query: 313 TLSPLFW 319
+ F+
Sbjct: 297 FIDGEFF 303
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 209 bits (511), Expect = 7e-53
Identities = 118/303 (38%), Positives = 182/303 (60%), Gaps = 19/303 (6%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L+NG +P G LGT +E + +V KSV AI GYRHID A+IY E++VG AI+
Sbjct: 24 LSNGDRMPLLG----LGTGKSESR--QVYKSVREAIKIGYRHIDCASIYGNEEEVGDAIR 77
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
I + R +L++T+KLW+ H K V AL +SL+NL +DY++LYLIHWP+ +
Sbjct: 78 DAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPEK 137
Query: 150 SISQT--DYV--------ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVL 199
+ +++ D + ETW+AM ++GLTK IGVSNF +++L++L S P V
Sbjct: 138 TFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQKPEVN 197
Query: 200 QVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQ--PSAPAPRADDQRLV-AIAQKY 256
QVE + LQQP L++YC ++ I++ AY+P G++ Q AP D ++ AIA+
Sbjct: 198 QVEHHPLLQQPTLIEYCASEEILITAYSPLGSMDRPQSLKVKDAPAVLDHPVIRAIAETR 257
Query: 257 KKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSP 316
+ Q+VL + V+ G+ IPKS+ R+ EN+Q D L+ E+Q +++ D +R ++
Sbjct: 258 GCSPAQVVLAWDVQRGISAIPKSVKPSRLLENLQAADIQLSNTELQKIEALDQNFRLVNG 317
Query: 317 LFW 319
FW
Sbjct: 318 AFW 320
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 209 bits (511), Expect = 7e-53
Identities = 114/299 (38%), Positives = 174/299 (58%), Gaps = 24/299 (8%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KLNNGKEIP G+GTW + L+G ++ A+ GYRHIDTA IY E +G +
Sbjct: 7 KLNNGKEIPTVGLGTWGMEDEAVLEG-----AIRNALSLGYRHIDTAFIYGNEKMIGNIL 61
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH-- 146
KK EGVV+R+DLF+T+KLWNT H LR+SL +L +DYVDLYLIHWP+
Sbjct: 62 KKLFDEGVVQRKDLFITSKLWNTFH--GCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPA 119
Query: 147 ---------DNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPS 197
++ + D V W+ M +++ GL KSIG+SNF E++ + P+
Sbjct: 120 PDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPA 179
Query: 198 VLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYK 257
+Q+E++ L Q L+++ K++GI V++Y+ G+ P + A DD+ + AIA+KY
Sbjct: 180 AIQIELHPYLNQKELVEFMKSKGIQVISYSSLGS----APGSSAKVRDDKTIKAIAKKYG 235
Query: 258 KTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSP 316
QI+L Y+ G+ IPKS K+ + ENI + + L+ ++I + + + G+R + P
Sbjct: 236 CAPSQIILSYITAQGICVIPKSRSKEHLRENIDLKE--LSREDISAIDALNTGHRYVDP 292
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 209 bits (510), Expect = 9e-53
Identities = 108/287 (37%), Positives = 171/287 (59%), Gaps = 16/287 (5%)
Query: 58 QKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEA 117
Q++ E AI AGYRHIDTA Y E VG AI+ KI +G+++R+D+F+ +KLW T+H E
Sbjct: 3 QRACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPED 62
Query: 118 VLPALRKSLKNLDLDYVDLYLIHWPIAL----------HDNASI-SQTDYVETWQAMTDV 166
+ KSL +L LDY+D YL+H+P+ L D + + DYV+ W+ M +
Sbjct: 63 IPVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEAL 122
Query: 167 LNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAY 226
G KSIGVSNF ++Q++RL S + P+V QVE++ L Q L+DYCK++ I + A+
Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAH 182
Query: 227 TPFGN-----LFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLH 281
+PFG+ F P +D +V +A+K+++T Q++LRY ++ + IPKS+
Sbjct: 183 SPFGSPGRPLEFQTGDEDPMGLLEDPVVVDVARKHRRTPAQVLLRYHIQQDIAVIPKSVK 242
Query: 282 KDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFWAHSPYFPFE 328
+ EN +I+DF+L +++ LKS + G+R ++PF+
Sbjct: 243 PHHILENTKIFDFTLDEEDMNALKSLNRGWRACIITELEAHYFYPFK 289
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 209 bits (510), Expect = 9e-53
Identities = 119/319 (37%), Positives = 184/319 (57%), Gaps = 23/319 (7%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KLN G IP +GTW + +EV +V AI+ GYRHID A IY E ++G A+
Sbjct: 9 KLNTGASIPAMALGTWQSSK------EEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEAL 62
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
+ + EG VKRE+LFVT+KLW +H + VLPA + +LKNL LDY+DLYLIH P+A
Sbjct: 63 SEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKG 122
Query: 149 A----SISQ--TDYV-----ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPS 197
SI++ Y TWQAM ++ +GL K+IGVSNF++++L +L + P+
Sbjct: 123 VRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIVPA 182
Query: 198 VLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGN---LFNRQPSAPAPRADDQRLV-AIA 253
QVE++ L Q L ++C ++GI++ AY+P GN L ++ P+ ++ ++ IA
Sbjct: 183 CNQVELHPYLPQEKLKEFCDSKGILLTAYSPLGNPGRLVPKERLEREPKVMEEPVIKEIA 242
Query: 254 QKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
K+ +V +++LR+ ++ G +PKS +D + +N LT DE+ +KS R
Sbjct: 243 AKHNCSVARVLLRWGIQRGYPVLPKSTSRDHLHDNFSALGLVLTDDEMAAIKSITTRQRY 302
Query: 314 LSP-LFWAHSPYF-PFESK 330
L+ +A Y PF+ +
Sbjct: 303 LTQGWMYAEGEYVDPFDGE 321
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 207 bits (506), Expect = 3e-52
Identities = 115/288 (39%), Positives = 168/288 (58%), Gaps = 26/288 (9%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P + L +G IP FG+GT+ EL +E V+ AI+ GYRHIDTA++Y+ E +VG
Sbjct: 10 PSVLLGDGVSIPQFGLGTY------ELPPNEASSVVQSAIELGYRHIDTASLYANEREVG 63
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
RAI A +KRE+ FVTTKLWN++ K A +SL L LDYVDLYLIHWP
Sbjct: 64 RAI----ASSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWPCPP 117
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
+ Y+ W+ + ++ G KS+GVSNF + ++++K G PSV Q+E++
Sbjct: 118 SEL-------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQIELHP 170
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
LQQ L+ C+ GI + ++ PF + P L A++Y KT Q++L
Sbjct: 171 WLQQRELVLSCRNDGIQIESWGPFARFSKDLDAFP-------ELTRPAKQYGKTPAQVIL 223
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
R+ ++ G + PK++H +R+ +NI I+DF LTPDEI + S D G+RT
Sbjct: 224 RWHIQKGYVVFPKTVHAERLRQNIDIFDFDLTPDEISGIDSLDAGFRT 271
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 206 bits (504), Expect = 5e-52
Identities = 108/280 (38%), Positives = 164/280 (58%), Gaps = 17/280 (6%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG +IP G GT+ D +++V+ AI+ GYRHIDTAA+Y E+ VG+ IK
Sbjct: 13 LNNGVKIPCVGYGTF------RTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGIK 66
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
+ +KREDLFVT+KLWNTN E A +++L L +DY+DLYLIHWP
Sbjct: 67 ----DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFG 122
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
+ ETW+AM D+ N+G ++IGVSNF + L V P+V Q+E++
Sbjct: 123 DDAAKINAETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVHPGWPH 182
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
++ Y +A I+V A+ P G + + P ++ IA KY+KT Q+ LR+++
Sbjct: 183 TEVVKYLQAHNILVEAWAPLGGQGAKVLTNPT-------MIQIADKYQKTPAQVCLRWVL 235
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDN 309
+ G++P+PKS+HK+R+ N I+DF LT ++++ + N
Sbjct: 236 QQGILPLPKSVHKERMISNQNIFDFELTDEDMRKISLLPN 275
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 206 bits (502), Expect = 8e-52
Identities = 113/301 (37%), Positives = 176/301 (58%), Gaps = 19/301 (6%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
+L NG ++P FG+GT+ + +E+ + A+D GYRHIDTA +Y E Q+G A+
Sbjct: 9 ELCNGSKLPVFGLGTY-----KVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDAL 63
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH-D 147
++ EG KREDLF+ TKL++ + K V +R+SL+NL +Y+DLYL+H+ + D
Sbjct: 64 QEIYKEGKYKREDLFLVTKLFSNKNTK--VEDQVRQSLQNLQTNYIDLYLLHYASSPPTD 121
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
++ + W +++ +GL ++IG+SNFN+Q L L S + P V Q+E+N+
Sbjct: 122 QFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIEVNVYC 181
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
QQP LL++CK + V AY P N +D L ++ KYKK+V QI+L++
Sbjct: 182 QQPRLLEFCKKLNLHVTAYCPLARCQNTD--------NDALLTELSTKYKKSVCQIMLQF 233
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPL---FWAHSPY 324
L+ LGV IPK+ + +R+ ENI+ DFSL +I LK + +R + P +W PY
Sbjct: 234 LLSLGVSVIPKTQNLERLRENIESTDFSLDEADIAKLKGLNKNFRLIDPYDREWWKRVPY 293
Query: 325 F 325
F
Sbjct: 294 F 294
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 206 bits (502), Expect = 8e-52
Identities = 113/286 (39%), Positives = 168/286 (58%), Gaps = 19/286 (6%)
Query: 27 VLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGR 86
++ L+NG ++P FG+G W G+ + +V WA+ AGYRHIDTAAIY E+ VG
Sbjct: 8 MVTLSNGVKMPQFGLGVWQSP-----AGEVTENAVNWALCAGYRHIDTAAIYKNEESVGA 62
Query: 87 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH 146
++ A GV RED+F+TTKLWNT E+ L A +S + L +DY+DLYLIHWP
Sbjct: 63 GLR---ASGV-PREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG-K 117
Query: 147 DNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 206
D S Y+++W+A + + ++IGVSNF+I LE + + VTP V QVE++
Sbjct: 118 DILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPL 177
Query: 207 LQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLR 266
Q L +C A+ I V A++P G + S P L AI KY KT Q++LR
Sbjct: 178 NNQADLRAFCDAKQIKVEAWSPLGQ--GKLLSNPI-------LSAIGAKYNKTAAQVILR 228
Query: 267 YLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
+ ++ +I IPKS+H++R+EEN I+DF L +++ + + + R
Sbjct: 229 WNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSR 274
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 204 bits (497), Expect = 3e-51
Identities = 118/286 (41%), Positives = 164/286 (57%), Gaps = 23/286 (8%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
L LNNG +IP G GTW + G SV A+ AGYRHIDTAA Y E+
Sbjct: 7 LTDTYTLNNGTKIPIVGFGTWQTPD-----GQVAYDSVLAALKAGYRHIDTAAAYGNEES 61
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHW-- 141
VG+AI A+ V REDLFVTTKLWN +H +A AL SL L LDYVDLYLIHW
Sbjct: 62 VGKAI----ADSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPN 117
Query: 142 PIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQV 201
P A+ DN D TW+AM + ++IGVSNF + L+ L V P+V Q+
Sbjct: 118 PAAMRDNWEQLNAD---TWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQI 174
Query: 202 EINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVP 261
+N + + ++ Y + I+ AY+P G + S P L +A KY K+V
Sbjct: 175 FLNPSDMEDEVVAYNRKHDILSEAYSPLGT--GKIFSIP-------ELKTLADKYDKSVA 225
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSF 307
Q+VLR+ ++ G +P+PKS+H DR+E+N +++DF L+ D+++++ F
Sbjct: 226 QVVLRWSLQHGFLPLPKSVHADRIEQNTELFDFELSDDDMKVIDGF 271
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 204 bits (497), Expect = 3e-51
Identities = 113/308 (36%), Positives = 182/308 (59%), Gaps = 15/308 (4%)
Query: 31 NNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKK 90
+ G+++P G+GT + + V+K+V A+ GYRH DTAA+Y++E +G AI +
Sbjct: 12 SGGRKMPVLGLGT---AADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQPLGDAIAE 68
Query: 91 KIAEGVVK-REDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN- 148
+ EG++K R++LF+T+KLW ++ +E V PAL+K+LKNL L+Y+D+YLIHWP++
Sbjct: 69 ALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVSSKPGN 128
Query: 149 -------ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQV 201
Q DY W+AM + GLTK+IGVSNF+ ++L + + V P+V QV
Sbjct: 129 YEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLANAKVPPAVNQV 188
Query: 202 EINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVP 261
E+N QQ L ++CK+ GI+VVAY G + + + L IA+ TV
Sbjct: 189 EVNPCWQQKQLTEFCKSNGILVVAYAALGAVGTFYGTNRV--MGSEVLNEIARIRGNTVA 246
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFWA- 320
Q+ LR+ E G+ + KS +K+R+E+N+QI++++L+ DE + + G L + +
Sbjct: 247 QVCLRWAYEQGIGVLVKSFNKERMEQNLQIFNWTLSDDESKKISEIPQGRACLGTDYTSV 306
Query: 321 HSPYFPFE 328
H P+ E
Sbjct: 307 HGPFKTIE 314
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 203 bits (496), Expect = 4e-51
Identities = 117/289 (40%), Positives = 169/289 (58%), Gaps = 27/289 (9%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
L +KL+NG E+P FG+G + N G+E +SV+ AI GYR IDTAAIY E+
Sbjct: 5 LKDTVKLHNGVEMPWFGLGVFKVEN-----GNEATESVKAAIKNGYRSIDTAAIYKNEEG 59
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
VG IK E V RE+LF+T+K+WN + E L A KSL+ L LDY+DLYLIHWP
Sbjct: 60 VGIGIK----ESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP- 114
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
+ Y +TW+A+ + G ++IGVSNF + LE L + + P V QVE
Sbjct: 115 --------GKDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEF 166
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+ L Q L DYCKAQGI + A++P L Q D++ L IA+K+ K+V Q+
Sbjct: 167 HPRLTQKELRDYCKAQGIQLEAWSP---LMQGQ------LLDNEVLTQIAEKHNKSVAQV 217
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
+LR+ ++ V+ IPKS+ + R+ EN I+DF L+ +++ + + + R
Sbjct: 218 ILRWDLQHEVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDER 266
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 203 bits (495), Expect = 6e-51
Identities = 104/253 (41%), Positives = 159/253 (62%), Gaps = 11/253 (4%)
Query: 56 EVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKK 115
+ ++++ A+ GYRH DTAA Y +E +G A+K+ I G+V R+DLFVT+KLW T +
Sbjct: 37 DTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHP 96
Query: 116 EAVLPALRKSLKNLDLDYVDLYLIHWPIALH--------DNASISQTDYVETWQAMTDVL 167
VLPALRKSLK L L+Y+DLYLIHWP++ + + D W++M +
Sbjct: 97 HLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQ 156
Query: 168 NQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYT 227
GLTK+IGVSNF++++L+ L S + P V QVE+NL QQ L ++CK GI+V A++
Sbjct: 157 KLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAFS 216
Query: 228 PFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEE 287
P +R P+ ++ L IA+ + K++ Q+ LR+L E GV +PKS K+R+ +
Sbjct: 217 PLRKGASRGPNEV---MENDVLKEIAEAHGKSIAQVSLRWLYEQGVTFVPKSYDKERMNQ 273
Query: 288 NIQIYDFSLTPDE 300
N+ I+D++LT +
Sbjct: 274 NLHIFDWALTEQD 286
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 202 bits (492), Expect = 1e-50
Identities = 115/309 (37%), Positives = 176/309 (56%), Gaps = 25/309 (8%)
Query: 20 PSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYS 79
P A LKL++G EIP G+GT + +K DE+ ++ A++ GYRHIDTA Y
Sbjct: 18 PGAQAVEKLKLSSGHEIPAVGLGT------STIKLDEMDNAISSALENGYRHIDTAFSYD 71
Query: 80 TEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLI 139
E +G+ +KK +G KRED+F+T+KL + ++ ++V L++SLK+L LDYVD+YLI
Sbjct: 72 NEAAIGKILKKWFDKGG-KREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLI 130
Query: 140 HWPIALHDNASISQ------------TDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLER 187
H P A+ + ++S D+ W+AM + +G KSIG+SNFN Q+
Sbjct: 131 HTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLN 190
Query: 188 LKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFG------NLFNRQPSAPA 241
+ + + PS LQVE + LQQ L +CK IV+ AY P G NL P
Sbjct: 191 IYNNAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAPLGSHNARLNLHRGTPKELP 250
Query: 242 PRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEI 301
+ + ++A KY K+ QI+LR+ ++ G++ IPKS + R + NI I+DF LT +E+
Sbjct: 251 ALVELPLIKSLAAKYNKSPGQILLRHTIQEGLVAIPKSSNAQRQKSNIDIFDFKLTDEEM 310
Query: 302 QLLKSFDNG 310
+ + + D G
Sbjct: 311 KKIDALDKG 319
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 201 bits (491), Expect = 2e-50
Identities = 116/287 (40%), Positives = 171/287 (59%), Gaps = 25/287 (8%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P + LNNG E+P G G W ++ D+ Q +V A++AGYR IDTAAIY E+ G
Sbjct: 6 PPIILNNGVEMPQLGFGVW------QVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTG 59
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
RAI A G+ REDLFVTTKLWN++ ++ L A S+ L L+Y+DLYLIHWP+
Sbjct: 60 RAIA---ASGLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPA 115
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
+ YV+T++A +L G ++IGVSNF + LERL +E V P+V Q+E++
Sbjct: 116 KER-------YVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQIELHP 168
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
+LQQ A + QGI A++P G + D +VAIAQK+ +T Q+VL
Sbjct: 169 HLQQHAAREVHAEQGIATEAWSPLG--------SGKGILDIPAIVAIAQKHGRTPAQVVL 220
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
R+ ++LG + IPKS+ R++ENI ++ FSL +++ + + + R
Sbjct: 221 RWHLQLGNVVIPKSVTPSRIKENIDVFGFSLDTEDLAAISALNEDRR 267
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 201 bits (491), Expect = 2e-50
Identities = 121/311 (38%), Positives = 170/311 (54%), Gaps = 33/311 (10%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
L KLN+G IP G+GTWL K EV+ +VE A+ AGYRHID AA Y E++
Sbjct: 3 LGRTFKLNSGYNIPAIGLGTWLS------KPHEVENAVEAALRAGYRHIDAAACYQNENE 56
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
VG KK V R+ +F+T+KLWNT+H E V A+ K+LK+L DY+DLYLIHWP+
Sbjct: 57 VGNGWKKS----GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPV 112
Query: 144 AL-HDNASISQTDYV------------ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKS 190
A H N +++ D V +TW A+ ++ +SIG+SNF +++ L
Sbjct: 113 AFEHTNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLK 172
Query: 191 EGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFG-NLFNRQPSAPAPR-ADDQR 248
+ P+V Q+E + LQQP L Y K + I+ VAY+P G N++N APR DD
Sbjct: 173 TAKIPPAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSPLGNNIYN------APRVVDDPD 226
Query: 249 LVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
+ AIA K K +++ + V+ G +PKS+ R+E N Q DF + E + L D
Sbjct: 227 VKAIADKLGKDPAALLISWAVQRGTAVLPKSVTPSRIESNFQ--DFIIPDAEFEALNKLD 284
Query: 309 NGYRTLSPLFW 319
R P W
Sbjct: 285 RNQRYNFPFRW 295
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 200 bits (487), Expect = 5e-50
Identities = 117/316 (37%), Positives = 176/316 (55%), Gaps = 29/316 (9%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+ NG E+P G+GTW EV ++V A++AGYRH+D A IY E +VG A
Sbjct: 4 ISFENGDEMPMIGLGTWKSPPG------EVYEAVTTALEAGYRHVDCAPIYKNETEVGAA 57
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
+ G ++R+D++VT+KLWN H + V PAL ++L +L LD +DLYLIHWP+AL
Sbjct: 58 LSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQP 117
Query: 148 NASI--SQTDYV--------ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPS 197
S D+V ETW AM + GL + IGVSNF++ L+ + G V P
Sbjct: 118 EVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPE 177
Query: 198 VLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQ-RLVA----- 251
+ QVE++ L QP L+ + +A I + AY+P G+ +P A +ADD+ L+A
Sbjct: 178 MNQVEMHPYLPQPELVSFAEAHNIPITAYSPLGS--GDRPD--AMKADDEPTLMANPTIN 233
Query: 252 -IAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
IA ++ + Q++L++ V G IPKS +++N+ D L+ DE++ + S D+
Sbjct: 234 DIADRHGVSPAQVLLQWGVARGTAVIPKSTTPAHIKDNLAAADLDLSADELETIDSLDSK 293
Query: 311 YRTLSPLFWA--HSPY 324
YR L+ W SPY
Sbjct: 294 YRYLAGAAWTMEGSPY 309
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 199 bits (486), Expect = 7e-50
Identities = 111/299 (37%), Positives = 179/299 (59%), Gaps = 25/299 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L NG+ +P G GTW + + E++ ++ A++AGYRHIDTA Y E +G +K
Sbjct: 8 LPNGELMPIIGFGTW------QAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLK 61
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA----- 144
+KR D+F+ TKL ++ E V ++ SL+NL L+Y+DLYLIH PI
Sbjct: 62 NWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVG 121
Query: 145 --LH---DNASI---SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTP 196
LH +N I + T++VE W M + G TK+IG+SNFNI Q++R+ +
Sbjct: 122 DILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMKI 181
Query: 197 SVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGN-----LFNRQPSAPAPRADDQRLVA 251
S+LQ+E+++ QQ L+ +CK + I + AY+P G+ L N+ +D ++
Sbjct: 182 SMLQIELHVYFQQKELVKFCKQENIPITAYSPLGSRSLIKLLNKTEEISDMLQNDV-VME 240
Query: 252 IAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
IA+KYKK+ QI+LRY+V+ G++ IPKS++ R++ENIQ++D+ + P++++ L + D G
Sbjct: 241 IAKKYKKSSAQILLRYIVQNGIVVIPKSINPQRIKENIQLFDWEINPEDMKKLYNLDRG 299
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 199 bits (485), Expect = 9e-50
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 27/290 (9%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
L + LNNG +P G+G W T S G E +++V A++AGYRHIDTA IY E
Sbjct: 8 LKQTIMLNNGISMPILGLGVWK-TKS----GKECKEAVLNALEAGYRHIDTARIYDNEVD 62
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
VG+AI+ E + R+++F+TTKLWN + + AL SL L +D+VDLYLIH+P+
Sbjct: 63 VGQAIR----ESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPV 118
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
+ +++W+ + + + L K+IGVSN+ I L L +TP+V QVE
Sbjct: 119 T---------SKRMDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEF 169
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+ L Q LL+YCK I + AY+P A + +D + IAQKY KT QI
Sbjct: 170 HPFLNQIHLLEYCKKHKIQLEAYSPL---------AHGQKIEDPTIAKIAQKYDKTPAQI 220
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
++R+ +E ++ IPKS+ K+R+ EN +++DF+++ +++++L S D +RT
Sbjct: 221 LIRWAIEQKIVVIPKSIKKERIIENSKVFDFAISEEDMKILNSLDEDFRT 270
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 198 bits (484), Expect = 1e-49
Identities = 114/318 (35%), Positives = 174/318 (54%), Gaps = 22/318 (6%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+ LN G ++P FG+GTW + EL ++ A+DAGYR IDTA +Y E +G+
Sbjct: 6 IPLNTGAQLPLFGLGTWQVKDEAELT-----VALRAALDAGYRLIDTAHLYQNEHIIGKV 60
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI---- 143
+ + I+ G +KRED+FVT+KL T H E V + LK L L+Y+DLYLIH P
Sbjct: 61 LHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKH 120
Query: 144 ------ALHDNASISQTD--YVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVT 195
L +N ++ T+ +++TW+A+ + +G K++GVSNF+ QL+ L V
Sbjct: 121 QEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVK 180
Query: 196 PSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNR--QPSAPAPRAD---DQRLV 250
P+ QVE ++ Q L CK G+ V AY P G+ + +P P D + +
Sbjct: 181 PANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPGRKAARPDGVWPEGDPLLEPIVK 240
Query: 251 AIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
+A KY KT QI++R+L + G+ IPKS+ DR+ ENI +DF L+ +++ L S +
Sbjct: 241 QLAAKYHKTAAQILIRHLTQHGISTIPKSVSPDRIVENISTFDFKLSDEDMHTLNSIETR 300
Query: 311 YRTLSPLFWAHSPYFPFE 328
R F P+FP +
Sbjct: 301 TRLFIADFAVKHPFFPHD 318
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 198 bits (482), Expect = 2e-49
Identities = 108/281 (38%), Positives = 165/281 (58%), Gaps = 27/281 (9%)
Query: 53 KGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTN 112
K +V+ +V+ AID GYRHID A +Y E +VG +K+K VVKRED+F+T+KLWN
Sbjct: 8 KPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNK 67
Query: 113 HKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLT 172
H + V A +LKNL L YVDLYL+HWP+A +QAM ++ G
Sbjct: 68 HHPDDVEQACDITLKNLQLSYVDLYLMHWPMA---------------YQAMEKLVTSGKC 112
Query: 173 KSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNL 232
K+IG+SNF+++ ++R+ + + P+ LQVE++ L Q L+++CK + V AY+P G
Sbjct: 113 KAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSPLG-- 170
Query: 233 FNRQPSAPAPRADDQRLV------AIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVE 286
P P + DD +L+ IA K K+ QI++R+ +E G+I IPKS+ R++
Sbjct: 171 ---APDRPWVKDDDPKLMEDPIVTGIATKKGKSPAQILIRFCLERGIICIPKSVTPSRIQ 227
Query: 287 ENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFWAHSPYFPF 327
N + +F L P++++ L + + GYR L W + P PF
Sbjct: 228 ANFEALNFELDPEDLKTLLAMNIGYRGCL-LDWVNHPQHPF 267
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 197 bits (481), Expect = 3e-49
Identities = 108/290 (37%), Positives = 179/290 (61%), Gaps = 15/290 (5%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P + LN+G ++P G+GT + + + D + AI GYRH D+A++Y TE+ +G
Sbjct: 7 PEVLLNSGHKMPVIGMGTSVESRPSN---DVLASIFVDAIQVGYRHFDSASVYGTEEAIG 63
Query: 86 RAIKKKIAEGVVK-REDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA 144
A+ K I +G++K R+++F+T+K WNT+ + ++PAL+ +LK L ++YVDLYLIHWP+
Sbjct: 64 MAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVR 123
Query: 145 L-HD--NASI-SQTDYVE-----TWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVT 195
L HD N I S+ D + TW+AM + GL KSIG+ N+ ++L +L +
Sbjct: 124 LRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIP 183
Query: 196 PSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQK 255
P+V QVE+N + QQ L ++CK +GI V A++P G S ++Q L IA
Sbjct: 184 PAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSPLGAYKIFWGSGAV--MENQILQDIATA 241
Query: 256 YKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLK 305
KT+ Q+ LR++ + G + KS +K+R+++N++I+DF L+ +E++ +K
Sbjct: 242 KGKTIAQVALRWVYQQGSSAMAKSFNKERMKQNLEIFDFELSEEELEKIK 291
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 197 bits (480), Expect = 4e-49
Identities = 115/308 (37%), Positives = 179/308 (58%), Gaps = 23/308 (7%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNGK +P G+GTWL EV K+V A++ GYR ID A Y E ++G
Sbjct: 8 LNNGKFMPAIGLGTWLAAPG------EVGKAVTLALENGYRLIDCARFYKNEKEIGEMGI 61
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
+ + RE+LFVT+KLW + + + +S+++L Y+DLYLIHWPIAL +A
Sbjct: 62 EPFLKNH-PREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKVDA 118
Query: 150 S-------ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVE 202
S D E WQ M ++++GL KSIG+SNF I Q+E++ + P + QVE
Sbjct: 119 SNPPKPEDFLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVE 178
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPR--ADDQRLVAIAQKYKKTV 260
+N+ LQQ L + CK+ IVV AY P G +P+ + + DD+ +V++A+KY KT
Sbjct: 179 LNVYLQQNKLREVCKSYNIVVEAYRPIGG----KPANESDKNCLDDEVVVSLAKKYNKTT 234
Query: 261 PQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLS-PLFW 319
QI LR+LV+ G+I +PKS + +R+ +N Q++++SL+ ++++ L+ + R + +W
Sbjct: 235 AQICLRWLVQNGIIAVPKSTNPNRLLQNYQVFEWSLSNEDMKALEKRNLNKRNVKFENYW 294
Query: 320 AHSPYFPF 327
Y F
Sbjct: 295 NGKTYEEF 302
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 196 bits (479), Expect = 5e-49
Identities = 113/310 (36%), Positives = 179/310 (57%), Gaps = 21/310 (6%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KLN G + P G+GTW S L GD V +V+ GYRHID A IY E ++G +
Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVGDAVAAAVK----IGYRHIDCAQIYGNEKEIGAVL 62
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
KK + VVKREDLF+T+KLW T+H + V AL ++LK+L L+YVDLYLIHWP +
Sbjct: 63 KKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKG 122
Query: 149 A------SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVE 202
+ ++ D TW+AM + + G ++IGVSNF+ ++L L V P+V QVE
Sbjct: 123 SVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVE 182
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRAD---DQRLVAIAQKYKKT 259
+ + +Q L ++CK++G+ + AY+P G+ P ++D + L +A+K K+
Sbjct: 183 CHPSWRQTKLQEFCKSKGVHLSAYSPLGS-----PGTTWLKSDVLKNPILNMVAEKLGKS 237
Query: 260 VPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFW 319
Q+ LR+ +++G +PKS ++ R++EN ++D+S+ PD + + R ++ F
Sbjct: 238 PAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI-PDYMFAKFAEIEQARLVTGSFL 296
Query: 320 AHSPYFPFES 329
H P++S
Sbjct: 297 VHETLSPYKS 306
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 196 bits (478), Expect = 7e-49
Identities = 116/293 (39%), Positives = 171/293 (58%), Gaps = 24/293 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LN+G IP G GT+ +K +QKS A+ GYR IDT AIY E+ VG+AIK
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKS--IQKS---ALTLGYRLIDTVAIYQNEEAVGKAIK 59
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
A GV+ RE++FVTTKLW N + AL +SL+ LDL+Y+DLYLIHWP A N
Sbjct: 60 ---ARGVL-REEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWP-ANAINY 114
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
Q +TW+AM ++ +G KS+GVSNF + LE L V+PSV Q+E + Q
Sbjct: 115 KDWQKTNADTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFHPGYWQ 174
Query: 210 PALLDYCKAQGIVVVAYTPF--GNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
P + ++CK GI V +++P G +F + L+ +++KY+K+V Q+ LR+
Sbjct: 175 PQVTEFCKNHGIAVESWSPLARGKVFG-----------NDLLIGLSKKYQKSVSQVCLRW 223
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDN-GYRTLSPLFW 319
+++ VI IPKS +R++ENI ++DF L+ +E++ + G+ P W
Sbjct: 224 IIQHDVIAIPKSSSPERIKENIDVFDFELSKEEMKKINELPQIGFSGELPNIW 276
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 196 bits (478), Expect = 7e-49
Identities = 119/296 (40%), Positives = 170/296 (57%), Gaps = 24/296 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG +IP G+GTWL D K+ A+ GY+HIDTAA Y EDQVGRAI
Sbjct: 14 LNNGLKIPAIGLGTWLADEE-----DAAYKATLTALKNGYKHIDTAAAYGNEDQVGRAI- 67
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
A+ V R+++FVTTKLWN HK AL +SLK L L+YVDLYLIHWP+++
Sbjct: 68 ---ADSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLSVDPKT 122
Query: 150 SISQTDY--VETWQAMTDVLNQG-LTKSIGVSNFNIQQLER-LKSEG-GVTPSVLQVEIN 204
DY V+TW+ + + +G K+IGVSNFN ++L++ L SEG V P + Q+E +
Sbjct: 123 EKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNSEGVNVVPVINQIEAH 182
Query: 205 LNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIV 264
L QP L DY K++ I + AY+P G+ A A ++ + IA+K+ Q++
Sbjct: 183 PLLTQPDLFDYLKSKDIYITAYSPLGH-------ADASTLKNKVVTDIAKKHNANAGQVL 235
Query: 265 LRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTP-DEIQLLKSFDNGYRTLSPLFW 319
+ + V+ G I IPKS +R+ +NI+ + S D + L+ + RT P F+
Sbjct: 236 ISWGVQRGTIVIPKSTTDERIIDNIKTFTLSQEDFDALNNLEKEEGEKRTNDPDFF 291
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 195 bits (476), Expect = 1e-48
Identities = 112/284 (39%), Positives = 166/284 (58%), Gaps = 25/284 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG +P G G + ++ EV ++V A+ GYR IDTA IY E VGRA+K
Sbjct: 6 LNNGLVMPQLGYGVF------KVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRALK 59
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
+ + RED+F+TTK+WN + E L A SL+ L +DYVDLYLIHWP+ D
Sbjct: 60 ----DSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPMPDEDL- 114
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
Y++TW+A+ + G K+IGVSNF+I L R+ EG V P+V Q+E++ L Q
Sbjct: 115 ------YMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIELHPFLSQ 168
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
A+ +C+ GIVV A++P L + + P D IA ++ KT Q+VLR+ +
Sbjct: 169 EAIRAFCQKNGIVVEAWSP---LMKGRDALTDPVITD-----IAARHGKTPAQVVLRWHL 220
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
+ +I IPKS+ R++EN+ I+DF L+PD+++ + + RT
Sbjct: 221 QHDIIAIPKSVTPSRIQENLDIFDFVLSPDDMRQIDQLNRNERT 264
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 195 bits (476), Expect = 1e-48
Identities = 107/282 (37%), Positives = 166/282 (58%), Gaps = 14/282 (4%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
L+ G+ +P G+GT +S + + + A++ G+RH DTAA+Y TE +G A
Sbjct: 9 LRHGAGRPMPAVGVGT---ADSAATSPETKRGAALAALEVGFRHFDTAALYGTEAPLGEA 65
Query: 88 IKKKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH 146
I + G+V RE++FVTTKLW T VLP+LR+SL+NL ++YVDLYL+HWPI++
Sbjct: 66 IAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPISVK 125
Query: 147 DNASISQT--------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
+ D+ W+AM + GL K+IGVSNF + L++L + + P+V
Sbjct: 126 PGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVATIPPAV 185
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKK 258
QVE+N QQ + +YC A+GI V AY+P G + L IA+ K
Sbjct: 186 NQVEMNPVWQQRTVREYCAAKGIRVAAYSPLGG--QNWIGEGNDVMESPVLADIARARGK 243
Query: 259 TVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDE 300
++ Q+ LR++ E GV PIPKS +K+R+++N++I+D+ LT ++
Sbjct: 244 SIAQVSLRWIHEQGVTPIPKSYNKERLKQNLEIFDWELTKED 285
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 195 bits (476), Expect = 1e-48
Identities = 113/298 (37%), Positives = 174/298 (58%), Gaps = 27/298 (9%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
+LN G++IP G GTW N+ E +V A+ AGYRHIDTAA+Y TE +GRA+
Sbjct: 9 RLNTGEDIPAIGFGTWQDENAQE-------DAVLTALSAGYRHIDTAAVYGTEKAIGRAL 61
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL--- 145
A + R++LF+T+KLWN H+ E V A+ +SLKNL++DY+DLYL+HWP A
Sbjct: 62 ----ARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPG 117
Query: 146 -----HDNASISQT---DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPS 197
D+ S+T DYV+T++AM ++ G TK+IG+SNF+ ++ERL + P+
Sbjct: 118 DDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCSIVPA 177
Query: 198 VLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAP---APRADDQRLVAIAQ 254
V+Q+E++ LQQ +++ K++GI V Y+ GN N S +D L AI
Sbjct: 178 VMQMELHPWLQQNDFVEWLKSKGIHVTQYSSLGNQ-NEVYSGRERYGRLIEDPALAAIGT 236
Query: 255 KYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
KY KT Q+ L + + G + KS R+++N + DF L ++++ +++ D R
Sbjct: 237 KYGKTGAQVALAWGITKGHSVLVKSKTPHRIQQNFE-SDFELKQEDMKAIENIDKKLR 293
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 195 bits (475), Expect = 2e-48
Identities = 110/275 (40%), Positives = 161/275 (58%), Gaps = 27/275 (9%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KLN G ++P G+GTW + K DEV+ +V A+ GYRHID AA+Y E +VG +
Sbjct: 8 KLNTGYDMPAVGLGTW------QSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM 61
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
+ GV RE++F+T+KLWNT+H E V A+ KSL +L DY+DLYLIHWP+A +
Sbjct: 62 R---LSGV-PREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYS 117
Query: 149 ASISQT--------DYVE-----TWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVT 195
+ Q D V+ TW AM ++ +G +SIGVSNF +++E L +T
Sbjct: 118 TTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKIT 177
Query: 196 PSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQK 255
P+V Q+E + LQQ LL++ +GIVV Y+P GN P A DD ++ A+K
Sbjct: 178 PAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSPLGNNIYNIPRA----VDDPLVIETAKK 233
Query: 256 YKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQ 290
KT Q+++ + V+ G + +PKS+ +R+E N Q
Sbjct: 234 LNKTPAQVLISWAVQRGTVVLPKSVTPERIESNFQ 268
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 195 bits (475), Expect = 2e-48
Identities = 112/289 (38%), Positives = 164/289 (56%), Gaps = 32/289 (11%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P + LN+G IP G G + ++ + Q++VE A++ GYRHIDTAAIY E+ VG
Sbjct: 4 PSIVLNDGNSIPQLGYGVF------KVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVG 57
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
AI A G+ R+DLF+TTKLWN H + A+ +SL L LD VDLYL+HWP
Sbjct: 58 AAIA---ASGIA-RDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPA 113
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
DN YV W+ M ++ GLT+SIGVSN + LER+ + GV P+V Q+E++
Sbjct: 114 ADN-------YVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHP 166
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFG----NLFNRQPSAPAPRADDQRLVAIAQKYKKTVP 261
QQ + D+ A + + ++ P G +LF +P + A A + KT
Sbjct: 167 AYQQREITDWAAAHDVKIESWGPLGQGKYDLFGAEP-----------VTAAAAAHGKTPA 215
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
Q VLR+ ++ G + PKS+ ++R+EEN+ ++DF LT EI + + D G
Sbjct: 216 QAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDAMDPG 264
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 194 bits (474), Expect = 2e-48
Identities = 110/316 (34%), Positives = 175/316 (55%), Gaps = 22/316 (6%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+ NG +P G GTW ++ +EV+K++ A++AGYRHIDTA +Y E +G+
Sbjct: 7 ITFENGTTMPALGFGTWRASD------EEVEKALNEALEAGYRHIDTAPVYLNEKTIGKV 60
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL-- 145
+K+ + G V R++LF+ TKL + V L+ SL +L L+YVDLY +H P +
Sbjct: 61 LKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPE 120
Query: 146 -------HDNASISQT--DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTP 196
D + +T D+V W+AM +V GL ++IG+SNFN +Q++R+ + P
Sbjct: 121 VDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKP 180
Query: 197 SVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNL-FNRQPSAPAPRADDQRLVA-IAQ 254
+ LQ+E ++ LQQP L+ +CKA GI V AY+P G+ + P D +V IA+
Sbjct: 181 ANLQIENHIYLQQPELVKFCKANGITVTAYSPLGSKGIEKLLGREVPDLLDNPVVKDIAE 240
Query: 255 KYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTL 314
K K+ Q++LR+L++ G+ IPKS + R+ +NI ++ F + ++ L D R
Sbjct: 241 KLGKSPAQVLLRHLLQRGISTIPKSTNPTRLRDNIDLFGFEIDDSDMVRLNQLDQNIRIC 300
Query: 315 SPLFW---AHSPYFPF 327
F+ P FPF
Sbjct: 301 DFGFFPGITKHPEFPF 316
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 194 bits (473), Expect = 3e-48
Identities = 111/287 (38%), Positives = 168/287 (58%), Gaps = 26/287 (9%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
+ P L L++G IP G+G W ++ D ++ A +AGYR IDTA IY E+
Sbjct: 58 MIPTLPLSDGTSIPQLGLGVW------QMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEG 111
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
VGRAI+ A G+ ++E L++TTK+WN+ ++ L A+R+SL L L+YVDLYLIHWP+
Sbjct: 112 VGRAIR---ASGLPRKE-LYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPV 167
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
D YV+TW+A+ + GL +SIGVSNF L+RL E G+ P V QVE+
Sbjct: 168 PKIDR-------YVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVEL 220
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+ LQQ L + IV A++P G Q + A D L IAQK+ ++ Q+
Sbjct: 221 HPRLQQHELRAFHAKHRIVTEAWSPLG-----QGTLLA----DPVLAGIAQKHGRSAAQV 271
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
++R+ ++ G++ IPKS+ R+ EN ++DF+L +++ + S D G
Sbjct: 272 IIRWHIQQGLVVIPKSVTPSRIAENANVFDFTLDAEDMAAIASLDAG 318
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 194 bits (473), Expect = 3e-48
Identities = 111/307 (36%), Positives = 169/307 (55%), Gaps = 27/307 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAI-DAGYRHIDTAAIYSTEDQVGRAI 88
L +G +P G+GTW G + SV AI +AGYRH+DTAA Y E +VG+ +
Sbjct: 18 LKSGHAMPAVGLGTWRA-------GSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGL 70
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
K + G+ R+DLFVT+K+W TN E V PAL +LK+L LDY+DLY IHWP L D
Sbjct: 71 KAAMEAGI-DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDG 129
Query: 149 A-------SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQV 201
A + + D W+ M +++ GL K IGV N+ + +L RL + P+V Q+
Sbjct: 130 AHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQM 189
Query: 202 EINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVP 261
E++ + + + CK GI V AY+P G S+ A D + +A K KT
Sbjct: 190 EMHPGWKNDKIFEACKKHGIHVTAYSPLG-------SSEKNLAHDPVVEKVANKLNKTPG 242
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLS--PLF- 318
Q+++++ ++ G IPKS +R++ENIQ++ + + ++ ++L S + R L+ LF
Sbjct: 243 QVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRVLTGEELFV 302
Query: 319 -WAHSPY 324
H PY
Sbjct: 303 NKTHGPY 309
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 192 bits (467), Expect = 1e-47
Identities = 117/300 (39%), Positives = 177/300 (59%), Gaps = 27/300 (9%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAI-DAGYRHIDTAAIYSTEDQVGRAIKKKIAE 94
IP G+GTW S +L ++ +AI +AGY HID A Y ED VG+A+++
Sbjct: 4 IPTIGLGTWKSPRSEDLVN-----AITYAIKEAGYVHIDCALCYENEDIVGQALQQCWDS 58
Query: 95 GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA---SI 151
G+ KRE++++T+KLWNT+H+ E V A RK+LK+L LDY+DLYL+H+P A + S+
Sbjct: 59 GI-KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSL 117
Query: 152 SQTD------------YVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLK-SEGGVTPSV 198
+ D ++TW+AM ++ +GL K IGVSN+ I QLERLK S+ TP
Sbjct: 118 NPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYT 177
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKK 258
QVE NL +QQ L +Y +GI+V Y+ G +P P D++ L IA + K
Sbjct: 178 NQVEFNLYMQQGPLREYMHKEGIIVTGYSTLGTPDWAKPDEPVVLKDEE-LNKIAAETGK 236
Query: 259 TVPQIVLRYL--VELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSP 316
+V ++ L++L +E G + KS+ +R+ +N + DF LT D+IQ L++ + YR + P
Sbjct: 237 SVGEVELKFLLTIEPGASLLAKSVTPERIYKNNHL-DFELTKDQIQRLRNRERFYRYVDP 295
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 192 bits (467), Expect = 1e-47
Identities = 103/285 (36%), Positives = 165/285 (57%), Gaps = 22/285 (7%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+KLNNG+EIP +G + N + + +WA DAGYRHID+AA Y E+ VGRA
Sbjct: 19 IKLNNGQEIPQVALGVYKAPNDGS-----TENACKWAFDAGYRHIDSAARYMNEESVGRA 73
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
+ + E V R ++F+T+KLW+ +H K A A+ SLK L++DY+D+YL+H P
Sbjct: 74 LAEWTKENNVPRSEIFITSKLWDADHDKAAA--AIEDSLKKLNVDYMDMYLMHSP----- 126
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
++ +E W+A+ + ++ G K+IGVSNF++++L+ L + + P+V Q+E +
Sbjct: 127 -GTMGAEKRLEAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIKPAVNQIESHPFF 185
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
L + C ++GI + AY+P A D + IA K+ KT QI+L++
Sbjct: 186 AHEELREACISRGIHIQAYSPM---------AQGQALDRPEIKTIASKHGKTPAQILLKW 236
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
+ G I +PKSL K R+E N Q++DF L D++ +L + D G +
Sbjct: 237 GLTHGNIILPKSLTKHRIESNAQLFDFELDSDDMDVLDNLDEGMK 281
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 192 bits (467), Expect = 1e-47
Identities = 119/291 (40%), Positives = 170/291 (58%), Gaps = 42/291 (14%)
Query: 27 VLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGR 86
+L LN G +IP G+GTW + K ++ K+V A+ GYRHIDTAAIY EDQVG+
Sbjct: 11 ILSLNTGAQIPQIGLGTW------QSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQ 64
Query: 87 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH 146
AIK + V RE++FVTTKLW T H + V AL +SLK L LDYVDLYL+HWP L
Sbjct: 65 AIK----DSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARL- 117
Query: 147 DNASISQTD--------------------YVETWQAMTDVLNQGLTKSIGVSNFNIQQLE 186
D A I D +++TW+ M ++ G TK++GVSNF+I L+
Sbjct: 118 DPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLK 177
Query: 187 RLKSEGG--VTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRA 244
L + G +TP+ QVEI+ L Q L+++CK++GIVV AY+P G S AP
Sbjct: 178 DLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLG-------STDAPLL 230
Query: 245 DDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFS 295
+ ++ IA+K +V+ + V+ G + +PKS++ DR++ N +I+ S
Sbjct: 231 KEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIFTLS 281
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 191 bits (465), Expect = 2e-47
Identities = 109/298 (36%), Positives = 173/298 (58%), Gaps = 23/298 (7%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
IP G+GT+L + LK V ++E D+GYRH+D AA Y ++ +G A+ + A+G
Sbjct: 4 IPSIGLGTFLAEDPAALKA-AVHSAIE---DSGYRHVDCAAYYKNQEIIGEALSEIFAKG 59
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNAS----- 150
VKRE++++T+K+WNT H+ + ++ ++K+LK L L+Y+DL L+HW A
Sbjct: 60 QVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLP 119
Query: 151 --------ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQ 200
D +ETW+AM + N GL K IGVSNF+I+QLER++ + GV P Q
Sbjct: 120 RDETGKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQ 179
Query: 201 VEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTV 260
VE ++ LQQ +LDY + + +++YT G + P P D L +A++ KT
Sbjct: 180 VESHMYLQQQPMLDYLTQRKMYMISYTCLGRATLKGPYG-YPLLQDPVLNEVAKEIGKTP 238
Query: 261 PQIVLRYLVELG--VIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSP 316
Q LR+L++L + IPKSL+ ++ NI + DF LT ++ + L+S G+R ++P
Sbjct: 239 AQTNLRFLLKLSPYAVVIPKSLNPANIKGNISL-DFDLTQEQFEKLRSRQCGWRFVNP 295
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 191 bits (465), Expect = 2e-47
Identities = 117/274 (42%), Positives = 158/274 (57%), Gaps = 31/274 (11%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAI-DAGYRHIDTAAIYSTEDQVGRAI 88
LNNGK IP G+GTW T +EV +VE A+ + GYRHIDTA Y ED VG I
Sbjct: 36 LNNGKTIPAIGLGTWKSTT------EEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGI 89
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
K+ + +GV KRED+FVTTK+W T H + V L SL+ L LDYVD+ LIHWP+ L+ N
Sbjct: 90 KRAMEKGV-KREDIFVTTKIWVTYHDR--VEENLDMSLERLGLDYVDMLLIHWPVPLNPN 146
Query: 149 AS-------------ISQT-DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV 194
+ I ++ +TW+ M VL G TKSIGVSNF+I LE L E V
Sbjct: 147 GNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAEV 206
Query: 195 TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQ 254
P+V QVE++ L Q L+++CK IV+ A++PFG S P ++ +V++A
Sbjct: 207 VPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPFG-------SVGGPLLKNELVVSLAD 259
Query: 255 KYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEEN 288
KY + I+ Y + G + IPKS+ R+ EN
Sbjct: 260 KYNTSPGGILTSYHIGNGTVVIPKSVTNSRIVEN 293
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 190 bits (463), Expect = 4e-47
Identities = 110/285 (38%), Positives = 168/285 (58%), Gaps = 23/285 (8%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P + LNNG E+P G G + ++ ++ ++ V AI GYR IDTAA Y E+ VG
Sbjct: 4 PKVTLNNGVEMPILGYGVF------QIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVG 57
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
RAIK+ I EG+V+RE+LFVTTKLW ++ E+ A KSLK L L+Y+DLYLIH P
Sbjct: 58 RAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG- 116
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
D W+AM ++ GL ++IGVSNF +L L + P+V Q+EI+
Sbjct: 117 ---------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIEIHP 167
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
Q+ +++ + I A+ PF R+ + L +IA+KY KTV Q++L
Sbjct: 168 FYQRQEEIEFMRNYNIQPEAWGPFAE--GRKNI-----FQNGVLRSIAEKYGKTVAQVIL 220
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
R+L + G++ IPK++ ++R++ENI I+DF LT ++++ + + D G
Sbjct: 221 RWLTQKGIVAIPKTVRRERMKENISIFDFELTQEDMEKIATLDEG 265
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 190 bits (463), Expect = 4e-47
Identities = 107/287 (37%), Positives = 163/287 (56%), Gaps = 26/287 (9%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P+++L +G +P G+G+W + ++ +++ A+D GYR IDTAAIY+ E VG
Sbjct: 5 PIIRLADGNHMPQLGLGSWASDDQ------QIAETIHAALDIGYRAIDTAAIYNNEKGVG 58
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
A++ E + RED+FVTTKLWN H AL +SL+ L LDYVDLYLIHWP
Sbjct: 59 NALQ----ETDIPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWPAPP 112
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
D YV WQ + ++ +GL +SIGVSNF + ++RL +E GV P + Q+E++
Sbjct: 113 QDQ-------YVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIELHP 165
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
LQQ L + IV +++P D+Q + + QKY KT Q+V+
Sbjct: 166 LLQQRQLHAWNATHNIVTESWSPLA-------QGGENVFDNQLVQHLTQKYGKTPAQVVI 218
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
R+ ++ G+I IPKS R++EN ++DF L +++ + + D G R
Sbjct: 219 RWHIDNGMIVIPKSTTLSRIKENFDVFDFKLEKEDLTAMTTLDIGKR 265
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 190 bits (462), Expect = 6e-47
Identities = 107/310 (34%), Positives = 174/310 (56%), Gaps = 15/310 (4%)
Query: 15 VIHLSPSAGLAPVLKLNNG---KEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRH 71
++ ++ S G A + + N ++IP FG+GTWL KG V +VE+A+ GYRH
Sbjct: 36 ILSIATSFGPAEMPEFNKNETVRDIPAFGLGTWLAG-----KG-VVVPAVEYALKGGYRH 89
Query: 72 IDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDL 131
IDTA I+ ED+VG+ IK A GV R++++VT KLWNT+H+ E V A+ S+ NL +
Sbjct: 90 IDTALIWRNEDEVGKGIK---ASGV-SRDEIWVTGKLWNTDHRPELVRKAIETSIANLGV 145
Query: 132 DYVDLYLIHWPIA-LHDNASI-SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLK 189
+Y+DLYLIH+P+A + + + + T ++TW+AM +++ GLT++IG SNF + + ++
Sbjct: 146 EYLDLYLIHYPVAWVPETRDVDNNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKIL 205
Query: 190 SEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRL 249
+ P + E + LQQ + +D+ K + I V+A +P N D+
Sbjct: 206 KIASIQPYAHEFETHPYLQQQSFVDFHKKENIKVIAASPLANTNPTYGDKYPSILHDEFW 265
Query: 250 VAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDN 309
V +A+ TV Q +L + + G I I KS H + + EN+ T E++ + D
Sbjct: 266 VKLAEDKNATVAQTILAWGQQRGTIVISKSTHSNHIAENLCSQGIEFTKSELEEVAKQDK 325
Query: 310 GYRTLSPLFW 319
R L+P+ W
Sbjct: 326 KLRLLNPIHW 335
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 189 bits (461), Expect = 8e-47
Identities = 112/303 (36%), Positives = 170/303 (56%), Gaps = 27/303 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
+N G +IP G GTW + K EV+ +VE A+ GYRHID AAIY E +VG I+
Sbjct: 9 INTGAKIPAVGFGTW------QAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR 62
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA----- 144
K V RE++F+T KLWNT H E V PAL K+L++L + Y+DLYL+HWP A
Sbjct: 63 KS----GVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGD 118
Query: 145 ----LHDNA--SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
L+D+ ++ DY+ T++AM +L G ++IGVSNFNI++LE L + V P+V
Sbjct: 119 KWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAV 178
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKK 258
Q+E + LQQP LL +C+++GI++ AY+P GN +P DD + +A +
Sbjct: 179 NQIEAHPYLQQPDLLQFCQSKGILIEAYSPLGNNQTGEPRT----VDDPLVHRVAGELSL 234
Query: 259 TVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLF 318
++ + V+ G + + KS+ R+ N+++ +L L S + R P
Sbjct: 235 DPGPLLASWGVQRGTVVLSKSVTPARIAANLRVR--ALPEGAFAQLNSLERHKRFNFPGH 292
Query: 319 WAH 321
W +
Sbjct: 293 WGY 295
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 189 bits (460), Expect = 1e-46
Identities = 107/303 (35%), Positives = 172/303 (56%), Gaps = 24/303 (7%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L++G E+P G+G W L+ DE+++ + AI GYRH D AA Y +E VG A+
Sbjct: 6 LSSGYEMPVIGLGLW------RLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALA 59
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI-----A 144
+ G+VKRE+LF+TTK+WN++H V+ A + SL+ L +DY+DLYL+H+P+ A
Sbjct: 60 EAFKTGLVKREELFITTKIWNSDHGH--VVEACKNSLEKLQIDYLDLYLVHYPMPTKHNA 117
Query: 145 LHDNASISQTDYV----------ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV 194
+ AS+ D V +TW+ M ++ GL +SIG+SN+ + + +
Sbjct: 118 IGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKI 177
Query: 195 TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGN-LFNRQPSAPAPRADDQRLVAIA 253
P+V Q E + Q+ +L+ +C G++ A+TP G N+ DD L +A
Sbjct: 178 KPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVA 237
Query: 254 QKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
+KY K+V QI LR+ ++ IPKS R++EN+++ +F L+ +++QL+ S D YRT
Sbjct: 238 KKYGKSVAQICLRWGIQRKTAVIPKSSKIQRLKENLEVLEFQLSDEDMQLIYSIDRKYRT 297
Query: 314 LSP 316
P
Sbjct: 298 SLP 300
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 187 bits (456), Expect = 3e-46
Identities = 103/280 (36%), Positives = 150/280 (53%), Gaps = 19/280 (6%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KLNN IP G GTW + G +++ AIDAGY+HID AAIY E VG I
Sbjct: 6 KLNNNINIPAIGFGTWQTPD-----GQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGI 60
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
K E + R+DLFVT+K+WN E L A ++ +L LDY+DLYLIHWP A H
Sbjct: 61 K----EANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQF 116
Query: 149 ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQ 208
+ Q + +TW AM + G K++GVSNF L L + P+V Q+E +
Sbjct: 117 ENWKQLNN-DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEYHPGYM 175
Query: 209 QPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYL 268
Q + +C I V ++P G D++ L +A KY KTV Q+ +R+
Sbjct: 176 QQDCVQFCNDNNIQVEGWSPLGR---------GDVFDNEVLKQLAHKYNKTVAQLSIRWA 226
Query: 269 VELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
++ VIP+PKS+ +R+ EN ++ DF+++ ++ L+ D
Sbjct: 227 IQNNVIPLPKSVTPNRIIENFEVSDFNISESDMALINKID 266
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 187 bits (456), Expect = 3e-46
Identities = 106/324 (32%), Positives = 181/324 (55%), Gaps = 27/324 (8%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
+A + LN+G E+P G GTW +L + + V A++AGYRHID+A + +++
Sbjct: 3 IADTVTLNSGYEMPVIGYGTW------QLPKNLAAERVRDALEAGYRHIDSALSFKNQEE 56
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
V IK V+RE+LF+++K+WNT H + + + + L+ + Y+DL +IHWP
Sbjct: 57 VAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPF 116
Query: 144 ALHDNAS----------------ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLER 187
++ S DY+ETW+A+ D G +SIG++NFNI Q+E+
Sbjct: 117 GWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQ 176
Query: 188 LKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGN---LFNRQPSAPAPRA 244
+ ++G + P+VLQVE+N L Q + +C+ +GI++ A+ GN R+ P
Sbjct: 177 VWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPGSALYRKHEDP-NLL 235
Query: 245 DDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
++ L +IA+ + K+V Q+++R+ ++L + KS R+ +NI I+ F LT EI +
Sbjct: 236 YNETLQSIAKGHGKSVVQVLVRWAIDLRTTALVKSSESKRIRQNINIFKFRLTSQEIARI 295
Query: 305 KSFDNGYRTLSPLFWAHS-PYFPF 327
K+ + +R L+PL + PYFP+
Sbjct: 296 KALNIDFRILNPLLGNYDHPYFPW 319
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 187 bits (456), Expect = 3e-46
Identities = 109/290 (37%), Positives = 163/290 (56%), Gaps = 28/290 (9%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
+ P++KL +G+ +P G+G W + E + +V A++ GYR IDTAAIY E+
Sbjct: 3 MQPLIKLYDGRLMPQLGLGVW------QASIQETELAVSKALEVGYRSIDTAAIYKNEEG 56
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
VG+A+K V R++LF+TTKLWN + AL SL+ L LDYVDLYLIHWP
Sbjct: 57 VGKALKA----AAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWPD 110
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
D+ YV W+ + + QGL +SIGV NF+I L+RL E G+ P+V Q+E+
Sbjct: 111 PKQDH-------YVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIEL 163
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLV-AIAQKYKKTVPQ 262
+ LQQ L + I +++P + DQ ++ +AQ+Y KT Q
Sbjct: 164 HPLLQQRQLHAWNATHHIATESWSPL--------AQGGKGVFDQEIIRKLAQQYNKTPAQ 215
Query: 263 IVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
IV+R+ ++ G+I IPKS+ R+ EN +++DF L +E+ + D G R
Sbjct: 216 IVIRWHLDSGLIVIPKSVTPARIRENFEVFDFKLQKEELLAITKLDCGKR 265
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 187 bits (455), Expect = 4e-46
Identities = 105/289 (36%), Positives = 159/289 (55%), Gaps = 24/289 (8%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
LA + LNNG +IPG G+G + ++ +E K VE I GYR IDTA IY E
Sbjct: 5 LADTVTLNNGTKIPGMGLGVF------QIPDEETAKVVEEGIINGYRLIDTAQIYGNESG 58
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
G IK +A + REDLFVT+K+WN + + + A SL+ L LDY+DLYLIHWP
Sbjct: 59 TGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWP- 117
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
Y E+WQA+ + +G K+IGVSNF + LE L S V P + QVE+
Sbjct: 118 --------GNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVEL 169
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+ L Q + D+C+ I V A++P L Q ++ ++AIA+ + K+ Q+
Sbjct: 170 HPKLDQKEVRDFCEKHDIKVQAWSP---LMQGQ------LLSNETILAIAENHNKSAAQV 220
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
+LR+ ++ ++ KS+HK+R+ N ++DF L+ +E+ + + R
Sbjct: 221 ILRWDIQQDILLAVKSVHKERMISNAAVFDFELSAEEMAQINQLNESLR 269
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 187 bits (455), Expect = 4e-46
Identities = 111/327 (33%), Positives = 178/327 (54%), Gaps = 30/327 (9%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P +K+++ K +P G+G W ++ D ++V AI GYRH+D+AA Y E QVG
Sbjct: 8 PGVKVSS-KSMPAVGLGLW------KITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVG 60
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
I + IAEG+ RE+L++TTKLWNT H+ E V A R+S+ +L LDY+DLYL+H+PIAL
Sbjct: 61 EGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIAL 120
Query: 146 H--------------DNAS------ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL 185
D+++ + Q ETW AM ++ GL + IGV N++ L
Sbjct: 121 RYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYSAVLL 180
Query: 186 ERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN---RQPSAPAP 242
L S + P++LQ+E + L Q ALL ++ + V A++P G+L A
Sbjct: 181 HDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNMAVTAFSPLGSLSYVELNMAGANDT 240
Query: 243 RADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQ 302
D ++A AQ+ T Q+VLR+ ++ G IPK+ + R+ EN+ + +F+L +E+
Sbjct: 241 VLTDPSVLAAAQRNGVTAAQVVLRWGIQRGTAVIPKTSNPQRLIENLTLTEFTLNDEEMD 300
Query: 303 LLKSFDNGYRTLSPLFWAHSPYFPFES 329
+ + + +R P + + + F S
Sbjct: 301 AISALNQNHRFNDPAQFCEAAFNTFHS 327
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 186 bits (453), Expect = 7e-46
Identities = 112/292 (38%), Positives = 171/292 (58%), Gaps = 31/292 (10%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LN G +IP FG+GTW G KG ++++V AI +GYR ID A +Y E++VG+ I+
Sbjct: 8 LNTGAKIPAFGLGTWQGD-----KG-VIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIR 61
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL---- 145
+ I+ G+VKREDLFV +K W T + + L +SLK L LDYVDLYL+HWPI +
Sbjct: 62 EAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMNPEG 119
Query: 146 -------HDNAS---ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVT 195
H + S I ++V+TW+ M + G TK++GVSN++ LE+L
Sbjct: 120 NDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTV 179
Query: 196 PSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQK 255
P+V QVE + L Q L+D+CK +GI ++AY+P G S P + +V IA+K
Sbjct: 180 PAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPLG-------STGGPLLTAEPVVKIAEK 232
Query: 256 YKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSF 307
+ + ++L Y + G+ IPKS++ DR++ N Q+ D L ++++LL +
Sbjct: 233 HSISPAAVLLGYQIARGITVIPKSVNPDRIKANAQLKD--LDAEDMKLLNDY 282
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 186 bits (452), Expect = 9e-46
Identities = 107/304 (35%), Positives = 160/304 (52%), Gaps = 25/304 (8%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAE- 94
+P G+GT+ + G + ++++ AID GYR DTA Y E VG AI++KI E
Sbjct: 17 LPTIGLGTY------SILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIREC 70
Query: 95 GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD------- 147
+ R+D F+ +KL + H+++ V R +L L +DYVDLYL+H P+AL
Sbjct: 71 NNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARN 130
Query: 148 ----NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
NA E W + +GL +SIGVSNFN Q+ L S+ + P+V Q+E
Sbjct: 131 GTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIEC 190
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
++ Q + +C+ Q I+V+ YTP G P + RL IA KT Q+
Sbjct: 191 SIGFNQRPMRKFCQQQNILVMGYTPLG-------KQKLPFLQNNRLKEIALSVDKTTAQV 243
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFWAHSP 323
LRYL++ GV+PI KS + R +EN+ I+DF LT +++ L + R F A +
Sbjct: 244 SLRYLIDEGVVPIVKSTDRKRQQENLDIFDFKLTKQQLEELDAIGGDQRACKMDFLAGAK 303
Query: 324 YFPF 327
+FPF
Sbjct: 304 HFPF 307
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 185 bits (451), Expect = 1e-45
Identities = 106/287 (36%), Positives = 160/287 (55%), Gaps = 26/287 (9%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P L +NNG +IP G+G + N+ + K +++WA+ AGYRHIDTAA Y E VG
Sbjct: 12 PDLPMNNGHQIPQLGLGVFQVDNAEDTKN-----AIKWALAAGYRHIDTAAYYGNEQWVG 66
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
AI+ E V R+ +FVT+KLWN+ + A +++L L LDY+DLYLIHWP
Sbjct: 67 EAIR----ESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPAP- 121
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
Y+++W+AM D+ G K+IGVSNFN Q+ + + G V P V Q+E +
Sbjct: 122 ---------GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQIETHP 172
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
QQ + Y ++QGI+ A++P G N D + +A + + QI+L
Sbjct: 173 YFQQNDMHAYLESQGILHEAWSPLGGGNNN-------ALTDSVINELAAAHDVSAAQIIL 225
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
R+ V+ + IPKS+H+ R+++N I+ F L DE++ + D G R
Sbjct: 226 RWHVQREEVVIPKSIHEARIQQNRDIFAFGLDEDEMKAISDLDTGKR 272
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 185 bits (450), Expect = 2e-45
Identities = 110/299 (36%), Positives = 168/299 (56%), Gaps = 38/299 (12%)
Query: 6 YSFVFVFAAVIHLSPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAI 65
++ + +F ++I +P++ KLN G IP G+GTW + K EV+++V A+
Sbjct: 22 FTILPIFNSLIMSAPTS-----FKLNTGASIPAIGLGTW------QAKAGEVRQAVAHAL 70
Query: 66 DAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKS 125
AGYRHID A Y ED+VG IK + V R ++F+T+K+W++ H + V L +
Sbjct: 71 KAGYRHIDGALCYQNEDEVGLGIK----DSGVPRSEIFLTSKVWSSYHDR--VEECLDTT 124
Query: 126 LKNLDLDYVDLYLIHWPIALHDNASIS--------------QTDYVETWQAMTDVLNQGL 171
LK+L DY+DLYLIHWP+ L N + D +TW M DVL +G
Sbjct: 125 LKSLQTDYLDLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGK 184
Query: 172 TKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGN 231
K+IG+SN I +E + G VTP+V QVE++ Q ALL YCK +GI++ AY+P G
Sbjct: 185 AKAIGLSNAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPLG- 243
Query: 232 LFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQ 290
S +P +D L+A+A+K+ +++ Y V GV+ +PKS+ R+E N++
Sbjct: 244 ------STSSPLHEDPDLLAVAKKHNVPTATVLISYQVNRGVVVLPKSVTPARIESNLK 296
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 184 bits (448), Expect = 3e-45
Identities = 110/313 (35%), Positives = 167/313 (53%), Gaps = 27/313 (8%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P KLN+G ++P G G W +NE D++ AI AGYR D A Y E + G
Sbjct: 4 PSTKLNSGYDMPLVGFGLW--KVNNETCADQIYH----AIKAGYRLFDGACDYGNEVEAG 57
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
+ + + I EG+VKREDLF+ +KLWN+ H + V P RK L + LDY DL+++H+PIAL
Sbjct: 58 KGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIAL 117
Query: 146 ----------------HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLK 189
++ S ETW AM ++++ L +SIGVSNF+ Q L L
Sbjct: 118 KYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLL 177
Query: 190 SEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNL----FNRQPSAPAPRAD 245
+ P+ LQ+E + L Q L+ Y + +GI V AY+ FG L + + + P+
Sbjct: 178 RYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFGPLSFVELDLKDAHETPKLF 237
Query: 246 DQRLV-AIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
D ++ IAQK+ KT Q++LR+ + + IPKS R+ +N+ + + L EI+++
Sbjct: 238 DHDVIKGIAQKHGKTPAQVLLRWATQRNIAVIPKSNDPTRLAQNLDVTGWDLETSEIEVI 297
Query: 305 KSFDNGYRTLSPL 317
S + R PL
Sbjct: 298 SSLNRNLRFNDPL 310
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 182 bits (444), Expect = 9e-45
Identities = 111/318 (34%), Positives = 179/318 (56%), Gaps = 28/318 (8%)
Query: 16 IHLSPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTA 75
I S + V +L++G P G+GT + L D ++ + A++ G HIDT+
Sbjct: 19 ISYSQNVEAGTVYRLSSGHNFPIVGLGT------HGLNEDVLETVLTGALEKGIGHIDTS 72
Query: 76 AIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVD 135
+Y E+ +G+ +K A+G KRED+FVT+KL ++ E+V ++ SL+ L L Y+D
Sbjct: 73 FVYKNEETIGKVLKDWFAKGG-KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLD 131
Query: 136 LYLIHWPIALH-----------DNASI---SQTDYVETWQAMTDVLNQGLTKSIGVSNFN 181
+YLIH P A+H ++ S+ +QTD + W+ M + +G TKSIG+SNFN
Sbjct: 132 MYLIHAPFAVHHKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFN 191
Query: 182 IQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPA 241
Q+ + E + PS LQVE++ QQ L+++C+ GI+V Y P G+ R+ P
Sbjct: 192 ETQITNILKEAKIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAPLGSPGARKELHPG 251
Query: 242 PRADDQRLV-------AIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDF 294
++ V IA+K+ K+V QI+L +LV+ G+ I S + + ++ENI+I+DF
Sbjct: 252 QMEEEFPDVFKLPVVNEIAKKHGKSVVQILLHHLVQKGIAVIFSSKNPNHLKENIEIFDF 311
Query: 295 SLTPDEIQLLKSFDNGYR 312
LT DE++ L + D G R
Sbjct: 312 ELTEDEMKSLDALDKGER 329
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 182 bits (444), Expect = 9e-45
Identities = 107/288 (37%), Positives = 166/288 (57%), Gaps = 26/288 (9%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
PV+K ++G +IP G G W ++ D ++V AI+ GYR ID A +Y E +G
Sbjct: 5 PVIKFHDGAQIPQVGFGIW------QVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLG 58
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
++ A G+ R+++FVTTK+WN ++ +SLK + ++ +DL LIHWP+
Sbjct: 59 EGLR---ASGL-PRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPVP- 113
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
SQ Y+ETW+A D+ ++GL +SIG SNFN LER+ +E G P + Q+E+N
Sbjct: 114 ------SQDLYLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQIELNP 167
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
LQQP + KA G+V A+TP GN + + + P + A+A+ K V Q++L
Sbjct: 168 MLQQPEMRAVHKAHGVVTQAWTPLGNARSFE-AEPITK-------AVARTGKSPV-QVIL 218
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
R+ V+LG IP+S+ R EN+ ++DF+LT E+ + + D G RT
Sbjct: 219 RWHVQLGNAVIPRSVKAHRQAENLDVFDFTLTEAEMSEIATLDMGLRT 266
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 182 bits (444), Expect = 9e-45
Identities = 100/290 (34%), Positives = 167/290 (57%), Gaps = 28/290 (9%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
L+ L++G +IP FG+G + +L +++V WA++ GYR IDTAA Y+ E +
Sbjct: 3 LSSTRTLSDGYKIPRFGLGLY------DLDEKHTKQAVLWALENGYRMIDTAASYNNEKR 56
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
VG A++ E V R ++++ TK+++T+H E + A +SL L +DYVDLYLIH+P+
Sbjct: 57 VGEALR----ESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPV 112
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
V +W+AM ++ +GLT+SIGVSNFNI LE L+ + P V Q+E+
Sbjct: 113 P---------AGVVGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEV 163
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+ LQ L+D+C+ I + AY+P + D L ++ KY KT Q+
Sbjct: 164 HPYLQMEELVDFCRKHSIAIQAYSPL---------TRGEKLHDPLLRSLGDKYGKTPAQV 214
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
+LR+ ++ G I I KS+ R+ EN+ +++F+++ ++++L + RT
Sbjct: 215 LLRWSLQKGYICISKSVQLSRIIENVDVFNFTISMADMEILDGLEENLRT 264
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 182 bits (444), Expect = 9e-45
Identities = 112/297 (37%), Positives = 162/297 (54%), Gaps = 32/297 (10%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LN G + G GTW + EV + V+ AI+ GYRH+D A +YS + +VG AIK
Sbjct: 7 LNTGASLELVGYGTW------QAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK 60
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
E VKREDLF+T+KLWN +H+ E V PAL +LK L L+Y+DLYLIHWP+A
Sbjct: 61 ----EAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEG 116
Query: 150 SISQ----------------TDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGG 193
I+Q V+TW+AM +L+ G K+IGVSNF+ + ++ + G
Sbjct: 117 DITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATG 176
Query: 194 VTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIA 253
VTPSV Q+E + L QP L+ + KA+ I + AY+P G N AP + IA
Sbjct: 177 VTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLG---NNTVGAPL-LVQHPEIKRIA 232
Query: 254 QKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
+K T Q+++ + + G IPKS+ R+ EN + SL+ +++ + G
Sbjct: 233 EKNGCTPAQVLIAWAIVGGHSVIPKSVTPSRIGENFK--QVSLSQEDVDAVSKLGEG 287
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 182 bits (442), Expect = 2e-44
Identities = 107/303 (35%), Positives = 172/303 (56%), Gaps = 27/303 (8%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+KL++G ++P G+GTW ++ + ++ +V A+++GYRHIDTA Y E+ +G+
Sbjct: 28 IKLSSGHDMPMIGLGTW------QMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIGKT 81
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA--- 144
+KK +G KREDLF+TTKL + E V L+ SL+ L L+YV++YLIH P A
Sbjct: 82 LKKWFDKGG-KREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVK 140
Query: 145 --------LHDNASI---SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGG 193
L+ + S+ + TD+V W+AM + G +SIG+SNFN QL +
Sbjct: 141 DKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAE 200
Query: 194 VTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPA-----PRADDQR 248
+ PS LQ+E+ QQ + + C + I V A++ G+ + P D
Sbjct: 201 IKPSNLQIELQAYNQQRPMRELCAERNITVTAFSTLGSPGSSPDKKTRYIKSLPTLFDHP 260
Query: 249 LVA-IAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSF 307
+V IA+ + +T Q++LR+ V+ G+I +PKS + R+++NI I+DF+LT DE+Q +
Sbjct: 261 IVKKIAEAHNRTSAQVLLRHAVQNGIIVLPKSTNPGRIKQNIGIFDFALTEDEMQAMNGL 320
Query: 308 DNG 310
D G
Sbjct: 321 DKG 323
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 181 bits (441), Expect = 2e-44
Identities = 101/283 (35%), Positives = 157/283 (55%), Gaps = 25/283 (8%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P L++N+GK P G+G W +L ++ SV AI+ GYRHIDTAAIY E+ VG
Sbjct: 9 PTLEMNDGKTTPQLGLGVW------QLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEAVG 62
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
RA+ + G V+RE+LF+TTKLWN + + A +S K L +DYVDLYL+HWP
Sbjct: 63 RAVADAVKAGDVQREELFITTKLWNAD--QACGKEAFAESQKKLGMDYVDLYLLHWPCPQ 120
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
D+ +V+ + +M ++ G SIGV NF + L+ LK + G TP+V Q+EI+
Sbjct: 121 ADS-------FVQAYDSMAEIQQSGGATSIGVCNFYPEALDALK-QAGHTPAVNQIEIHP 172
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
Q + +GIV A++P G D + IA ++ +V Q ++
Sbjct: 173 GFSQAEQRSDNRDRGIVTEAWSPLGQ---------GQNLTDPTIAKIAAEHGVSVAQAII 223
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
R+ ++ G + IP+S +RV +N ++ F L+ DE+ +++ D
Sbjct: 224 RWHIQRGDVVIPRSSKVERVRQNFDVFGFELSADEVSAIEALD 266
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 180 bits (439), Expect = 3e-44
Identities = 108/292 (36%), Positives = 161/292 (55%), Gaps = 32/292 (10%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L NG +IP G GTW ++ ++ +V AI GYRHID A Y ED V IK
Sbjct: 14 LANGAQIPKLGFGTW------KMSKEQATPAVAHAIKTGYRHIDCAWAYRNEDAVAAGIK 67
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN- 148
K V R L++T+KLWN+ H E V AL SLK+L DY+DLYL+HWP+A ++
Sbjct: 68 K----AGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSK 123
Query: 149 ----ASISQT------------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEG 192
SI T D++ T++ M +++ +G ++IGVSNFNI++ + E
Sbjct: 124 GSMVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEA 183
Query: 193 GVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAI 252
+ P V QVE+NL + L +Y A G+ + AY+PFG+ N A +D +V +
Sbjct: 184 SIKPVVNQVEVNLGVHNEELRNYAHAHGVTLQAYSPFGSNQN-----VAKSLEDPVVVDV 238
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
AQ+ T Q++L + + +IPI KS+ +R+EEN ++ D L +EI+ L
Sbjct: 239 AQRNNITPAQVLLAWTLGRDIIPISKSVTPERIEENFRVLDIQLAEEEIKHL 290
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 180 bits (438), Expect = 5e-44
Identities = 106/299 (35%), Positives = 166/299 (55%), Gaps = 27/299 (9%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+K NG +IP G G + N KG++ + +V AI GYRH DTA IY E +G A
Sbjct: 8 IKAVNGIKIPQVGFGVY---KLN--KGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLA 62
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
I+K + RE+ F+T+K+WNT+H EA A ++ K L+++Y+D+YLIH+
Sbjct: 63 IEKS----QIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHF------ 112
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
+ + Y+ETW AM ++ QG K IGV+NF IQ LE L +TP + Q+E +
Sbjct: 113 ----ASSYYLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITPMINQIETHPEF 168
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
Q L Y I+ A+ P G ++ L IA ++KTV Q++LR+
Sbjct: 169 PQNELHQYLTKHKILHEAWAPLGQ-------GNKALLENTVLKKIASNHEKTVAQVILRW 221
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR-TLSPLFWAHSPYF 325
++ G+I IPKS + R++ENIQ++DF L+ +E++ + + G R + SP + +P +
Sbjct: 222 HIQRGIIIIPKSSNPKRIKENIQLFDFELSSEEMEKINQLNTGKRYSHSPTGYMINPLY 280
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 180 bits (437), Expect = 6e-44
Identities = 106/283 (37%), Positives = 162/283 (57%), Gaps = 26/283 (9%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+KLNNG E+P G GT+ T++ E +++V+ AI AGYRHIDTA Y E+ VGR
Sbjct: 4 VKLNNGIEVPILGFGTYQITDAGE-----AEQAVKEAIAAGYRHIDTAQSYMNEEAVGRG 58
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
I A GV R++LF+TTK+W N + V+ + +SLK L LDY+DL LIH P
Sbjct: 59 IA---ASGV-DRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPY---- 110
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
D W AM ++ QG K+IGVSNF + ++ L + +TP V Q+EIN
Sbjct: 111 ------NDVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEINPFQ 164
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
QQ ++ + +G+ V A+ PF N + P L IA+KY K+V Q++LR+
Sbjct: 165 QQSKNIEALRKEGVAVEAWAPFAEGKNDIFTNPI-------LTKIAEKYGKSVAQVILRW 217
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
L+E +I + KS+ +R+ +N+ ++DF L+ ++ + + + G
Sbjct: 218 LIEQDIIVLAKSVKPERMAQNLAVFDFELSEEDKSAIATLNQG 260
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 179 bits (436), Expect = 8e-44
Identities = 108/295 (36%), Positives = 166/295 (56%), Gaps = 25/295 (8%)
Query: 35 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAID-AGYRHIDTAAIYSTEDQVGRAIKKKIA 93
EIP G GT+L + +LK ++ +AI+ G RHIDTA Y ++ +G +K+ A
Sbjct: 2 EIPQLGFGTYLANDPAKLKA-----ALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFA 56
Query: 94 EGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD------ 147
+G +KRED+F+TTKLW T+H+K+ V P L ++L L L YVDL+LIH PIA
Sbjct: 57 KGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDG 116
Query: 148 ---------NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
Q D +ET+ AM + +GLT+ IGVSNF+I+QLER+ + P
Sbjct: 117 TMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYA 176
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKK 258
QVE N+ Q LL YC++ I ++A+T G+ + P + +D + +A + KK
Sbjct: 177 NQVECNIYRQFKPLLSYCESHNIYLMAHTTIGHPPLKGPFGTS-LLEDPVVKQVASEAKK 235
Query: 259 TVPQIVLRYLVELG--VIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGY 311
T QI L++L + I IP S++ ++ N ++ DF+LT +++ L+ D Y
Sbjct: 236 TSAQICLKFLQQKSKMYILIPMSMNPKNIKSNYEL-DFTLTEQQMKKLEELDRFY 289
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 178 bits (434), Expect = 1e-43
Identities = 108/292 (36%), Positives = 156/292 (53%), Gaps = 27/292 (9%)
Query: 21 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 80
+AG+ P + LN+G IP G+G EL E ++SV A++AGYR IDTAA+Y
Sbjct: 8 AAGI-PSVSLNDGHSIPVLGLGV------GELSEAEAERSVAAALEAGYRLIDTAAVYGN 60
Query: 81 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIH 140
E VGRA+ A G+ RE+++VTTKL + A R SL+ L LDYVDLYLIH
Sbjct: 61 EAAVGRAVN---ASGI-PREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIH 116
Query: 141 WPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQ 200
WP H Y+++W + G+ +SIGV NFN + L + TP++ Q
Sbjct: 117 WPAGDHGK-------YIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQ 169
Query: 201 VEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTV 260
+E++ L Q L + GIV AY P G D + +AQ + KT
Sbjct: 170 IELHPLLNQAELREVNAGYGIVTEAYGPLG---------VGRLLDHAAVTGVAQAHGKTP 220
Query: 261 PQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
Q++LR+ ++LG + I +S + DR+ N++++DF LT DE+ L D G R
Sbjct: 221 AQVLLRWSIQLGNVVIARSANPDRITSNLEVFDFELTDDEMATLNGLDEGTR 272
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 178 bits (433), Expect = 2e-43
Identities = 103/286 (36%), Positives = 160/286 (55%), Gaps = 22/286 (7%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAI-DAGYRHIDTAAIYSTEDQV 84
P + L+NG IP G+GT G ++V +A+ + G RHIDTA Y E+ +
Sbjct: 14 PAVPLHNGLNIPILGLGT-------SHYGGYSHEAVLYALQECGIRHIDTAKRYGCEEAL 66
Query: 85 GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA 144
G+A+ E V+RE+L+VTTKLW ++ ++ A R S L +DY+DLYL+HWP +
Sbjct: 67 GKAV----TESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWPDS 122
Query: 145 LHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEIN 204
+ S SQ +ETW+A+ ++ ++GL ++IGVSNF I L LK GG+ P V QVE +
Sbjct: 123 MVPGRS-SQEVRLETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHVNQVEFH 181
Query: 205 LNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIV 264
Q L+++C+ + IV Y P A ++ +A+KY ++ QI
Sbjct: 182 PFQQPMKLVEHCRKENIVFEGYCPL---------AKGQALTHPHILELAKKYGRSASQIC 232
Query: 265 LRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
+R+ ++ GV+ IPKS DR+ EN Q++ F L E+ L + +G
Sbjct: 233 IRWSIQNGVVTIPKSTKPDRIYENCQVFGFRLEDSEMAALSTLHDG 278
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 178 bits (433), Expect = 2e-43
Identities = 97/294 (32%), Positives = 161/294 (54%), Gaps = 22/294 (7%)
Query: 15 VIHLSPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDT 74
++ + + P + LN+G E+P G GT+ +L+ + ++V AI+ GYRHIDT
Sbjct: 1 MVTMKQHENIIPTITLNDGTEMPAIGFGTY------KLREQDAYRAVRSAIEVGYRHIDT 54
Query: 75 AAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYV 134
A++Y E++VGRA+ I G V R++LF+TTK+WN H + + ++SL L LDY+
Sbjct: 55 ASLYKNEEEVGRAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYI 114
Query: 135 DLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV 194
D ++HWP + YVE++ A+ + G +S+ V+NF + L + +E G+
Sbjct: 115 DCCMVHWPWP-------QKGLYVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGI 167
Query: 195 TPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQ 254
P + QVE++ Q + G+V A++P G R S A + + IAQ
Sbjct: 168 APVLNQVELHPGFSQAEQRAVDRELGVVTEAWSPLG----RGDSLNA-----EAITLIAQ 218
Query: 255 KYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
Y+KT Q+ LR++ +LG +PKS + R EN+ I+DF L +++ + S D
Sbjct: 219 CYEKTPAQVTLRWIHQLGCSVVPKSANPQRQRENLDIFDFELNTEDMNSITSLD 272
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 177 bits (432), Expect = 2e-43
Identities = 106/296 (35%), Positives = 161/296 (54%), Gaps = 22/296 (7%)
Query: 17 HLSPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAA 76
H++P+ P + L +G IP G+G + + V VE A++AGYRHID AA
Sbjct: 5 HINPAN--VPDIALKDGHSIPQVGLGVL------RIDDEGVVPVVESALEAGYRHIDGAA 56
Query: 77 IYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDL 136
Y+ E VGRA+ KRE L+VTTKL ++ ++ L A SLK L LDYVD+
Sbjct: 57 GYNNEAGVGRALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDM 116
Query: 137 YLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTP 196
Y+IHWP ++ +TW+A + ++G+ +++GV NF L+RL E G P
Sbjct: 117 YMIHWPTPFDWRST-------DTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWP 169
Query: 197 SVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKY 256
+V Q+E++ QQ ++ +CK GI V AY+P A D + IA +
Sbjct: 170 AVNQIELHPTWQQREVVAFCKEHGIAVEAYSPMAR-------GADLNAGDGTIEKIAAAH 222
Query: 257 KKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
+ + Q++LR+ +E G I IPKS+H DR +EN+ ++ F+LT DE + + D R
Sbjct: 223 EVSPAQVILRWHIENGTIIIPKSVHADRQKENLNLFGFALTADEHAAIDALDGPTR 278
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 177 bits (431), Expect = 3e-43
Identities = 107/287 (37%), Positives = 159/287 (55%), Gaps = 25/287 (8%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
L+PV++LN+G IP G+GTW L +V +V A++ GYRHIDTA Y E
Sbjct: 3 LSPVIELNDGHRIPQIGLGTW------PLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKG 56
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
VG I+ + G+ R +LF+TTKL ++ + L SLK L LDYVDL LIHWP+
Sbjct: 57 VGNGIR---SSGL-DRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL 112
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
D +++ TW+ + G +SIGVSNF LERL + V P+V Q+++
Sbjct: 113 PRRD-------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQV 165
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+ + + + Y + GIV +Y+P G A + + L IAQK+ KT QI
Sbjct: 166 SPAITRIVDIAYNRRHGIVTESYSPLG--------AGSDLLNAPVLGRIAQKHGKTPGQI 217
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
VLR+ VE G++ IPK+ + R++EN+ I+ F+L D+ + + D G
Sbjct: 218 VLRWHVEQGLVAIPKTANPQRMKENLDIFGFTLDADDTSAIATLDGG 264
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 177 bits (430), Expect = 4e-43
Identities = 111/309 (35%), Positives = 180/309 (58%), Gaps = 24/309 (7%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
++LN+G +P G GT+ ++ + + E K AID G+RHID+A +Y E++VG+A
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
I +KIA+G VKRE++F T KLW T + E V PAL +SLK L DYVDL++IH P A+
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQ 127
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV--TPSVLQ-VEIN 204
D + + +++ + + +LE + ++ G+ P+ Q VE +
Sbjct: 128 PGK---------ELLPKDASGEIILETVELC--DTWELELILNKPGLRYKPTCNQVVECH 176
Query: 205 LNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQ---PSAPAPRADDQRLVAIAQKYKKTVP 261
L Q LL++CK++ IV+VAY+ G+ + Q P P ++ L +IA+K+ ++
Sbjct: 177 PYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCP-HLLEEPILKSIAKKHSRSPG 235
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFWAH 321
Q+ LRY ++ GV+ + KS ++R++EN QI+DF LTP++ +K+ D R L A+
Sbjct: 236 QVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPED---MKAIDGLNRNLRYDNAAN 292
Query: 322 SPYFPFESK 330
PYFPF +
Sbjct: 293 HPYFPFSEE 301
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 176 bits (429), Expect = 6e-43
Identities = 98/278 (35%), Positives = 161/278 (57%), Gaps = 25/278 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG +IP G GTW + G+ ++SV A++ GYRHIDTA+ Y ED VGRAI+
Sbjct: 12 LNNGVKIPIIGFGTWQTPD-----GEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ 66
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHW--PIALHD 147
K + R +LF+TTKLWN++H E A+ +SL +L LDY+D+YLIHW P ++ D
Sbjct: 67 KS----GINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSMRD 122
Query: 148 N-ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 206
+ A I+ E+W+AM + + G ++IGVSNF L+ L + P V Q+ +N +
Sbjct: 123 HWAEIN----AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFLNPS 178
Query: 207 LQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLR 266
Q ++ K ++ AY+P G ++ + +A Y K+ Q+++R
Sbjct: 179 DLQSEVVTENKKLDLLSEAYSPLGT---------GGLLGNEVVKEVAANYGKSTAQVLIR 229
Query: 267 YLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
+ ++ G +P+PKS+H + ++ N ++DF ++P+++ L
Sbjct: 230 WSLQHGFLPLPKSVHPEYIKANADVFDFEISPEDMAKL 267
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 176 bits (428), Expect = 8e-43
Identities = 105/295 (35%), Positives = 162/295 (54%), Gaps = 21/295 (7%)
Query: 22 AGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTE 81
AG +P++ LNNG ++P G+G + + +E ++ AI +GYR IDTA Y+ E
Sbjct: 2 AGKSPLINLNNGVKMPALGLGVFAAS------AEETASAIASAISSGYRLIDTARSYNNE 55
Query: 82 DQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHW 141
QVG I+ V R ++FVTTKL+N ++ E L A +SL L LDYVDLYL+HW
Sbjct: 56 AQVGEGIRNS----GVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHW 111
Query: 142 PIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQV 201
P NA+I ++W+A +L G ++IGV NF QL+ L + V P+V Q+
Sbjct: 112 P-TKDWNATI------QSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQI 164
Query: 202 EINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN----RQPSAPAPRADDQRLVAIAQKYK 257
E++ Q LL +A GIV A++P G N D + IA+ +
Sbjct: 165 ELHPYFAQKPLLAKNRALGIVTEAWSPIGGAINDGDGDNHGGRKHPLTDPVITTIAEAHG 224
Query: 258 KTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
++ Q++LR+ + V+ IPKS++ +R+ +NI ++DF+L+ E+ L D G R
Sbjct: 225 RSAAQVILRWHFQNDVVAIPKSVNPERIAKNIDVFDFALSDAEMAQLDELDTGVR 279
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 175 bits (427), Expect = 1e-42
Identities = 105/308 (34%), Positives = 166/308 (53%), Gaps = 28/308 (9%)
Query: 32 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKK 91
NG IP G+GTW + + +EV+ +V A+ AGY H+D AA Y+ E +VG A+++
Sbjct: 12 NGLRIPRVGLGTW------KARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALREA 65
Query: 92 IAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASI 151
G KRED+FVT+KLWN + V AL +L +L + Y+DLYLIHWP+A +
Sbjct: 66 FERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKRGTVL 125
Query: 152 ---SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSE--GGVTPSVLQVEINLN 206
++ E W + + GL + IGVSNFN QL L + + P+ Q+E +
Sbjct: 126 QPDAEASIAECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIESHPL 185
Query: 207 LQQPALLDYCKAQGIVVVAYTPF---GNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+L+ Y +++G+ V AY+P G LF +++ LV +A+KY T Q+
Sbjct: 186 WSNDSLVKYSQSKGLTVTAYSPLAQGGELF-----------ENEILVGLAKKYGVTPAQV 234
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFWAHSP 323
VLR+ V+ V+ IPKS R+ N ++ F L+ +++ +K D ++ + W S
Sbjct: 235 VLRWNVQRDVVVIPKSTSAKRIASNADLFGFELSDEDMDAMKVLD-VMKSCATAPW--SE 291
Query: 324 YFPFESKN 331
+ P S+N
Sbjct: 292 FAPVASRN 299
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 175 bits (426), Expect = 1e-42
Identities = 103/308 (33%), Positives = 174/308 (56%), Gaps = 12/308 (3%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
++LNNG ++P G+GT + +E+ + A+D GYR+ DTA Y E ++G+A
Sbjct: 15 VQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVEIGQA 74
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHW---PIA 144
+ +G KRED+F+TTKL+ +K+ + ++ SL L Y+DLYLI W P+
Sbjct: 75 FQNIFQQGKYKREDVFITTKLFPFKIEKK-IKEVVQNSLDQLQTSYIDLYLIQWSFTPVL 133
Query: 145 LHDNASIS--QTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVE 202
+ + S++ E W+ + + + G+ +SIGV+NFN Q + L S + P V Q+E
Sbjct: 134 TNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIE 193
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFGNL--FNRQPSAPAPRADDQRLVA-IAQKYKKT 259
+ L Q L+++ K I VA +P G F P + ++ + IAQK+KK+
Sbjct: 194 VTPYLPQIDLINFLKRCKIETVAISPLGRAGCFENTPEGMKIKLLEEDIFKQIAQKHKKS 253
Query: 260 VPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFW 319
V Q++LR LV+ ++ IPK+ DR++EN +I+DF LT ++++ + S +NG R ++
Sbjct: 254 VVQVILRCLVQREIMMIPKTAKLDRLKENSEIFDFELTEEDMKQIYSLENGTRAIN---L 310
Query: 320 AHSPYFPF 327
HS +F +
Sbjct: 311 KHSQWFGY 318
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 175 bits (425), Expect = 2e-42
Identities = 89/280 (31%), Positives = 163/280 (58%), Gaps = 19/280 (6%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L N ++P G GT+ + G + ++V+ A++ GYRH+D A IY + V + IK
Sbjct: 16 LANNYKMPSIGFGTYKLED-----GKQTVEAVKTALEVGYRHLDCAEIYENQLSVSQGIK 70
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
GV R+++F+T+K+WN + E+ A K LK+LDL+Y+DL LIHWPI
Sbjct: 71 ---LSGV-NRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKGFKD 126
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
+ + + +TW+AM + +G K+IG+SNF + +E LK + P V Q+E + Q
Sbjct: 127 NWQEVN-AQTWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQ 185
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
P +++YC+ IVV A++PF + + +++ LV +A+KY+ TV Q++L +++
Sbjct: 186 PEIVEYCQKNNIVVQAWSPF---------SQSKVLENKTLVQLAKKYEVTVAQLILNWII 236
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDN 309
+ ++P+PKS +R+ N +++F + +++++ ++
Sbjct: 237 QKDIVPLPKSKTPERIRSNFDVFNFGINQADLKVIDQLND 276
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 174 bits (424), Expect = 2e-42
Identities = 98/245 (40%), Positives = 153/245 (62%), Gaps = 26/245 (10%)
Query: 56 EVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTK------LW 109
+V+++V+ AIDAGYRHID A +Y E +VG AI++KI E VKREDLF+ +K LW
Sbjct: 47 KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWLW 106
Query: 110 NTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQ 169
T ++ V A K+LK+L L Y+D+YLIHWP + ++AM +++++
Sbjct: 107 TTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWP---------------QGFKAMEELVDE 151
Query: 170 GLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINLNLQQPALLDYCKAQGIVVVAYT 227
GL K++G+SNFN Q+E+L ++ G+ P QVE + L Q L+ YC ++GI + AY+
Sbjct: 152 GLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITITAYS 211
Query: 228 PFGNLFN--RQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRV 285
P G+ +P P+ ++ ++ IA K+KKT Q+++R+ ++ VI IPKS+ R+
Sbjct: 212 PLGSPDRPWAKPEDPS-LLEEPKIKEIAAKHKKTTAQVLIRFHIQRNVIVIPKSVTPARI 270
Query: 286 EENIQ 290
ENIQ
Sbjct: 271 VENIQ 275
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 174 bits (424), Expect = 2e-42
Identities = 101/289 (34%), Positives = 160/289 (55%), Gaps = 30/289 (10%)
Query: 20 PSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYS 79
PSA V+ ++G +P G+G W E DE + V+ A+ GYR +DTA +Y
Sbjct: 6 PSAEAQTVISFHDGHTMPQIGLGVW------ETPPDETAEVVKEAVKLGYRSVDTARLYK 59
Query: 80 TEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLI 139
E+ VG+ G+ ++F+TTKLWN ++ L A +S + L +DLYLI
Sbjct: 60 NEEGVGK--------GLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLI 111
Query: 140 HWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVL 199
HWP+ +Q YVETW+A+ ++ G KSIGVSNF + LER+ GV P V
Sbjct: 112 HWPMP-------AQGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVN 164
Query: 200 QVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKT 259
Q+E++ + QQ AL ++ + I ++ P G R S D+R+ IA+K+ +T
Sbjct: 165 QIELHPDFQQRALREFHEKHNIRTESWRPLGK--GRVLS-------DERIGKIAEKHSRT 215
Query: 260 VPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
Q+V+R+ ++ G+I IPKS++ R+ EN+ ++ F L D++Q ++ D
Sbjct: 216 PAQVVIRWHLQNGLIVIPKSVNPKRLAENLDVFGFVLDADDMQAIEQMD 264
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 174 bits (423), Expect = 3e-42
Identities = 107/307 (34%), Positives = 164/307 (53%), Gaps = 29/307 (9%)
Query: 35 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAE 94
++P G G W +++ + + ++ AI GYR D A Y E +VGR I K I E
Sbjct: 14 KMPLRGFGCW------KIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKE 67
Query: 95 GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH-------- 146
G+VKRE+LF+ TKLWNT H K+ V A + LK+ L+Y DLYLIH+PI L
Sbjct: 68 GLVKREELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSY 127
Query: 147 ---------DNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPS 197
D + ++ E W M ++ LT++IGV+NFN Q + L S + P+
Sbjct: 128 PPEWYVPHADKLNFERSPIHECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPA 187
Query: 198 VLQVEINLNLQQPALLDYCKAQGIVVVAYTPFG-----NLFNRQPSAPAPRADDQRLVAI 252
VLQ+EI+ L Q L+ + + QGI V AY+ FG +L + + A+ + +I
Sbjct: 188 VLQIEIHPLLPQERLVKWVQEQGIQVTAYSSFGPTSYVDLCESGKTYSSLLANAD-VKSI 246
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
A K+ QI+LRY ++ + IPKS+H+DR++ N+ I + L D+ ++L S R
Sbjct: 247 ANKHNANTGQILLRYALDRNIAVIPKSVHEDRMKSNLDILNIQLDQDDRKILNSLKTNQR 306
Query: 313 TLSPLFW 319
P+ +
Sbjct: 307 FNDPMIF 313
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 173 bits (422), Expect = 4e-42
Identities = 111/298 (37%), Positives = 157/298 (52%), Gaps = 29/298 (9%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P +KLN+G EIP G G + +N DE K+VE AI GYR IDTA Y+ + VG
Sbjct: 5 PKIKLNDGNEIPQLGFGVFQISNH-----DEAVKAVESAISNGYRLIDTAEAYNNQTAVG 59
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
AIK V R+D+F+TTKLW +N E A+ + LK L DY+D+ L+H
Sbjct: 60 EAIKNSD----VNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLHQAYG- 114
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
D W+A+ D G TKSIGVSNF QL L+ V P V Q+E+N
Sbjct: 115 ---------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIEVNP 165
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
Q+ + + + + V A+ PF + + P L I +KY K+ Q++L
Sbjct: 166 WFQREPEVKWNQKDDVAVEAWAPFAEGKDGIFTNPV-------LTEIGKKYGKSNGQVIL 218
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFWAHSP 323
R+L++ G+I IPKS+H R +ENI I+DF L D++Q + + D + +S F H P
Sbjct: 219 RWLIQRGIIVIPKSVHDARQKENIDIFDFELNNDDMQKIAALD---KNVSQFFDHHDP 273
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 173 bits (421), Expect = 5e-42
Identities = 101/291 (34%), Positives = 174/291 (59%), Gaps = 28/291 (9%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDE-VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
KLN G +IP G GT+ ++ G E + + +++A++AGYRHIDTA +Y E+ +G A
Sbjct: 35 KLNTGFDIPLAGFGTY------QIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTA 88
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEA-VLPALRKSLKNLDLDYVDLYLIHWPIALH 146
+K + + +KRED+F+T+KL + + K EA V +RKSL NL DY+DLYLIHWP
Sbjct: 89 LKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSG 148
Query: 147 D--------NASISQTDYVE----TWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSE-GG 193
++ D V+ +W A++ + +G +SIGVSN+ ++ L+ + ++ G
Sbjct: 149 KCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLADCKG 208
Query: 194 VTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIA 253
+ P+V QVE + QP LL+YC+ GI + AY+ G+ S A +D+ + ++A
Sbjct: 209 IVPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYSSLGS------SNTAELREDETVQSVA 262
Query: 254 QKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
+ +KT Q++LR+ +E V +PK+ +D ++EN+ + +F + ++++ L
Sbjct: 263 KSLQKTPVQVLLRWAIEQEVGILPKARSRDHIQENVGL-EFEIPAEQMKQL 312
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 173 bits (420), Expect = 7e-42
Identities = 101/288 (35%), Positives = 163/288 (56%), Gaps = 24/288 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LN+G +P G G WL N +V + A+ AG+RH DTA Y ED VGRA++
Sbjct: 8 LNDGYYMPRPGCGLWLIDNR------DVDSLIRQALKAGFRHFDTAQAYFNEDGVGRALR 61
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
V RE LF+T+K+ + L + ++L+ L ++Y++L+LIHWPI
Sbjct: 62 YT----EVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIP----- 112
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
++ YVETW+A ++ GL +SIGVSNF Q +ERL + GV P+V Q+E++ + QQ
Sbjct: 113 --AKNLYVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLELHPHFQQ 170
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
+ DY GI + +Y+PFG S A + ++ +A+++ + QIVLR+ +
Sbjct: 171 CDVRDYHHEAGIAIQSYSPFG-------SNGAAVLRNAVVMVLARRHDHSPAQIVLRWHL 223
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPL 317
+ G+ P+P++ + R EN+ ++DF L+ +E++LL S + PL
Sbjct: 224 QQGLTPLPRTTNGARFSENVDVWDFELSEEEMKLLASLNTRTGNTQPL 271
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 173 bits (420), Expect = 7e-42
Identities = 95/247 (38%), Positives = 147/247 (59%), Gaps = 12/247 (4%)
Query: 64 AIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPAL 122
AI+ GYRH DTA IY+TE VG A+ + + G++ R D+FVT+K+W ++ V+PA
Sbjct: 41 AIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAA 100
Query: 123 RKSLKNLDLDYVDLYLIHWPIAL----HD-----NASISQTDYVETWQAMTDVLNQGLTK 173
R++L+NL +DYVDL L+HWP++L +D + D W+ M + GL +
Sbjct: 101 RETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGMEECHRLGLAR 160
Query: 174 SIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLF 233
+IGVSNF+ ++LE+L S V P+V QVE+N QQ L + C+ +G+ + Y+P G
Sbjct: 161 AIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPLG--A 218
Query: 234 NRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYD 293
P A D L IA KT+ QI LR+L E G + + K+ ++ R++EN+ I++
Sbjct: 219 KGTPWGSAAVMDSGVLQEIAGAKGKTLAQICLRWLYEQGDVLLVKTYNEKRMKENLDIFN 278
Query: 294 FSLTPDE 300
+ LT +E
Sbjct: 279 WELTDEE 285
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 172 bits (419), Expect = 9e-42
Identities = 113/299 (37%), Positives = 164/299 (54%), Gaps = 53/299 (17%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KL++G ++P G+GTWL K EV+ +VE A+ GYRHID AA Y E++VG
Sbjct: 8 KLSSGYDMPAVGLGTWLS------KPHEVENAVETALRLGYRHIDAAACYLNENEVGNGW 61
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYL---------- 138
KK V R+ +F+T+KLWNT+H + V A+ K+LK+L DY+DLYL
Sbjct: 62 KKS----GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIH 117
Query: 139 ----------IHWPIAL-HDNASISQTDYV------------ETWQAMTDVLNQGLTKSI 175
IHWP+A H N +++ D V +TW A+ +++ G +SI
Sbjct: 118 DLLSLLTNNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSI 177
Query: 176 GVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQ--GIVVVAYTPFG-NL 232
GVSNF I+++E L + P+V Q+E + LQQPAL Y K + I+ VAY+P G N+
Sbjct: 178 GVSNFTIEKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSPLGNNI 237
Query: 233 FNRQPSAPAPR-ADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQ 290
+N APR DD + IAQK K +++ + V+ G +PKS+ R+E N Q
Sbjct: 238 YN------APRVVDDPTVKEIAQKLNKDPAALLISWAVQRGTSVLPKSVTPSRIESNFQ 290
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 172 bits (419), Expect = 9e-42
Identities = 125/327 (38%), Positives = 173/327 (52%), Gaps = 40/327 (12%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG IP G+GT N +E K E +++V+ AI AGYRHIDTA Y TE VG AIK
Sbjct: 27 LNNGVRIPALGLGT---ANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA---LH 146
+ + +G +KREDLF+TTK+W + V +L +SLK L L+YVDL L HWP+ +
Sbjct: 83 ELLEDGSIKREDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140
Query: 147 DNASIS-----------------QTDYVETWQAMTDVL---NQGLTKSIGVSNFNIQQLE 186
D IS DY+ET++ + + N ++IGVSNF+I+ LE
Sbjct: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200
Query: 187 RLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADD 246
RL E V P+V QVE + +L Q L +C I++ AY+P G S AP
Sbjct: 201 RLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLG-------SHGAPNLKI 253
Query: 247 QRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
+ +A+KY T +++ Y + G I IP+SL+ R+ +I+ SLT DE+Q L
Sbjct: 254 PLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQELND 311
Query: 307 FDNGY--RTLSPLFWAHSPYFPFESKN 331
F Y R + F A P F N
Sbjct: 312 FGEKYPVRFIDEPFAAILPEFTGNGPN 338
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 172 bits (418), Expect = 1e-41
Identities = 102/292 (34%), Positives = 162/292 (55%), Gaps = 25/292 (8%)
Query: 19 SPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 78
S SA P + LN+G+EIP G G + +++ + ++V+ A+D GYRHIDTA +Y
Sbjct: 6 SVSAMTVPTILLNDGREIPQLGFGVF------QIEPGDTAQAVKTALDLGYRHIDTAQMY 59
Query: 79 STEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYL 138
E +V + I A+ V R++++VT+KL N H+ +A A+ S++ L +DLYL
Sbjct: 60 GNEAEVAQGI----ADSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYL 114
Query: 139 IHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
IHWP+ ++ D+V TW+ + + G +SIGVSNF + L+RL E V P+V
Sbjct: 115 IHWPLP-----TLYGGDFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAV 169
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKK 258
Q+E++ + +C I V A++P A DD + A+A + K
Sbjct: 170 NQIEVHPYFGNEEVRRHCGEHQIGVEAWSPI---------AQGKVLDDPTVTAVANRLGK 220
Query: 259 TVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
+ Q+VLR+ VE G I PKS+ R+EEN ++DF LT +++ L+ + D G
Sbjct: 221 SPAQVVLRWHVERGDIVFPKSVTPSRMEENFALFDFELTEEDLALISALDKG 272
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 172 bits (418), Expect = 1e-41
Identities = 100/290 (34%), Positives = 153/290 (52%), Gaps = 17/290 (5%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P+L G IP G GT+ EL+ ++ V A+ GY HIDTA++Y E +
Sbjct: 14 PILNFREGGSIPQIGYGTY------ELRQNDCIIGVTEALKIGYTHIDTASVYRNEQDIA 67
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP--I 143
+ I A G+ KREDLF+T+K+ E A++ L L++ Y+D LIHWP
Sbjct: 68 KVIHNP-AYGI-KREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVS 125
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
L N + +ETW+A+ ++ G+ K IGVSNFNI L+ L + P + Q EI
Sbjct: 126 KLPPNDPKNAQIRLETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMNQFEI 185
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+ +++C+ GI+V AY+P + P + +AQKYKKTV Q+
Sbjct: 186 HPLCFNKKTIEFCQKNGILVEAYSPLARQHEKVMKHPL-------INQLAQKYKKTVAQV 238
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
+LR+ ++ ++ IPKS R++ENI I DF+L+P E++ + D T
Sbjct: 239 ILRWALQNNMVIIPKSKTPQRIQENIDILDFALSPQELEQMNQLDENLHT 288
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 171 bits (417), Expect = 2e-41
Identities = 102/284 (35%), Positives = 154/284 (54%), Gaps = 27/284 (9%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
+LNNG E+P G G + T+ ++ ++E A+D GYR DTA+ Y E ++G
Sbjct: 10 RLNNGIEMPRHGFGVYKLTDEQRMR-----TALETAVDVGYRLFDTASFYHNEKELGDFF 64
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
A +KR++ FVTTK+WNT + L A KS K L LD VDLYL+HWP
Sbjct: 65 ----ASSGLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP------ 114
Query: 149 ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQ 208
Q + ETW+A+ + ++GL ++IGVSNF L+RL++ V P V Q+E + +
Sbjct: 115 ---KQDTFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFP 171
Query: 209 QPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYL 268
L Y + IV A++P G +Q L+ +A+K+ K+ QIVLR+
Sbjct: 172 NQLLHRYLEELHIVHQAWSPLGR---------GGVLQEQILIDLAKKHGKSPAQIVLRWH 222
Query: 269 VELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
++ + IPKS R+ EN IYDF LT +++ ++ +NG R
Sbjct: 223 LQNNISIIPKSETPSRIRENADIYDFELTEADMRQVERLNNGER 266
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 171 bits (417), Expect = 2e-41
Identities = 108/283 (38%), Positives = 156/283 (55%), Gaps = 26/283 (9%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+KLNNG E+P G GT+ T++ E + +V+ AI AGYRHIDTA Y E+ VGR
Sbjct: 4 VKLNNGVEVPILGFGTYQITDAAE-----AEHAVKDAIKAGYRHIDTAQSYMNEEAVGRG 58
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
I A GV R++LF+TTK+W N + V+ + +SLK L LDYVDL LIH P
Sbjct: 59 IA---ASGV-DRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPF---- 110
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
D W AM ++ G ++IGVSNF+ ++ L + VTP V Q+E+N
Sbjct: 111 ------NDVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQ 164
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
QQ A L + +G+ + A+ PF N + P L I KY K+ Q++LR+
Sbjct: 165 QQTANLAILRKEGVAIEAWAPFAEGKNDIFNNPV-------LTKIGAKYGKSAAQVILRW 217
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
LVE +I + KS+ +R+ +N+ I+DF LT + + + D G
Sbjct: 218 LVEQDIIVLAKSVKPERMAQNLAIFDFELTEADKEEIAGLDQG 260
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 171 bits (416), Expect = 2e-41
Identities = 104/283 (36%), Positives = 154/283 (54%), Gaps = 23/283 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L+N ++P G G + T+ D ++SV AI GYR IDTAA+Y ED VG A++
Sbjct: 11 LSNNLKMPMMGFGVFQVTDK-----DVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVR 65
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPA-LRKSLKNLDLDYVDLYLIHWPIALHDN 148
+ I+EG+ RE+LF+T+KLW + + + A + SLK L+Y DLYL+H
Sbjct: 66 EAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQ------- 118
Query: 149 ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQ 208
+ DY W+A+ D +G K+IGVSNF L V P V QVE++
Sbjct: 119 ---AMRDYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELHPYFA 175
Query: 209 QPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYL 268
QP L K + A+ P G +P ++ L +IA ++K++ Q++LR+
Sbjct: 176 QPEALATMKYYNVQPEAWAPLGG-GRHKPF------ENNLLQSIADAHQKSISQVILRWN 228
Query: 269 VELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGY 311
++ GV+ IPKS H+ R+EEN I+DFSLT E+ + S D GY
Sbjct: 229 IQRGVVVIPKSTHQQRIEENFAIWDFSLTEKEMAQISSLDLGY 271
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 171 bits (415), Expect = 3e-41
Identities = 96/260 (36%), Positives = 143/260 (55%), Gaps = 22/260 (8%)
Query: 56 EVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKK 115
E + ++ A+ GYR +DTA+ Y E+ VG I A+ V R+DLF+TTK+WN +
Sbjct: 16 EAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGI----AKCGVPRKDLFITTKIWNNAQRL 71
Query: 116 EAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSI 175
V A ++SL L LDY+DLYLIHWP+ ++ TW+ M +L G SI
Sbjct: 72 GDVEGAFQRSLDRLGLDYIDLYLIHWPVP---------GCFLNTWKDMEKILESGRALSI 122
Query: 176 GVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNR 235
GVSNF I+ LE L+ G+ P+V Q+E + L++YC+A I V AY P
Sbjct: 123 GVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEYCQANDIQVQAYAPL------ 176
Query: 236 QPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFS 295
A D+ L + KY T QI LR+ V+ G+ IPKS+H +R+ N +I+DF+
Sbjct: 177 ---ARGAYLDNDVLCVLGTKYAHTPAQIGLRWAVQKGISVIPKSVHPERIASNARIFDFT 233
Query: 296 LTPDEIQLLKSFDNGYRTLS 315
+ +++ LL + + Y + S
Sbjct: 234 IDQEDMDLLDTLNQNYHSSS 253
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 171 bits (415), Expect = 3e-41
Identities = 104/293 (35%), Positives = 158/293 (53%), Gaps = 20/293 (6%)
Query: 21 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 80
+A P + LN+G +P G GT T +L ++ A+ GYRH+DTAA+Y T
Sbjct: 16 AATAVPCVTLNSGHAMPVLGFGTGSSTPPADLAA-----TIAHAVRLGYRHLDTAAVYGT 70
Query: 81 EDQVGRAIKKKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLI 139
E VG A+ + + G V R +LFVTTKL + V+ ALR+SL L LDYVDL+LI
Sbjct: 71 EGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLI 130
Query: 140 HWPIALHDNASISQT------------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLER 187
HWP+A+ + + D W+ M + GL +SIGVSNF+ ++ R
Sbjct: 131 HWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFSAAKMSR 190
Query: 188 LKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQ 247
L + V P+V QVE+N+ +Q + + C G+VV AY+P G S +
Sbjct: 191 LLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSPLGAHGAHWGSDAVMNSGVL 250
Query: 248 RLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDE 300
VA A+ KT+ Q+ LR+L E GV + +S ++ R+++N+ I+D+ L+ +
Sbjct: 251 HDVAAAR--CKTIAQVALRWLYEQGVCMVARSFNEGRMKQNMDIFDWELSDQD 301
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 169 bits (412), Expect = 7e-41
Identities = 99/289 (34%), Positives = 167/289 (57%), Gaps = 29/289 (10%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDA-GYRHIDTAAIYSTEDQVGR 86
+KL NG +P G+G + + +G+ + ++ AID GYR IDTA +Y E+ VG
Sbjct: 4 IKLANGLHMPIIGLGVY------KAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGN 57
Query: 87 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH 146
AIK+ +KRED+F+TTK+W +N+ + ++ KSLK L +Y+DL L+H P
Sbjct: 58 AIKQT----KIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG-- 111
Query: 147 DNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 206
DY W+A+ + +G+ K+IGVSNF +L V P + Q+E++
Sbjct: 112 --------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHPL 163
Query: 207 LQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLR 266
Q+ L + G+ V ++ FG A + ++ LV++A+KY KTVPQI+LR
Sbjct: 164 RQRIEDLHWNNKYGVAVESWASFGR-------ATSEIMENPILVSLAEKYNKTVPQIILR 216
Query: 267 YLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLS 315
+L++ ++ IPK++ + R++EN+ I+DF ++ D++ L+K+ N +T+S
Sbjct: 217 WLIQQNIVVIPKTVTESRLKENMDIFDFEISDDDMDLIKTI-NQNKTVS 264
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 169 bits (412), Expect = 7e-41
Identities = 101/283 (35%), Positives = 155/283 (54%), Gaps = 25/283 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG +P G+G + ++ +++++ V A+DAGYR DTA Y E +G A+K
Sbjct: 8 LNNGYPMPAVGLGVY------KIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSALK 61
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
V+R++LF+T+KLWN + + KSL NL LDY+DL+LIHWP +N
Sbjct: 62 ----HSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPC---END 114
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
+ Y+E+++A+ + +G K+IGV NF I LE+L E +TP V Q+E++ Q
Sbjct: 115 QL----YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPYFNQ 170
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
+ D+C I V A+ P + N+ DD + IA +Y KT QIVLR+ +
Sbjct: 171 QDVQDFCDEHDIKVTAWMPL--MRNK------GLLDDPVITDIAHRYDKTPAQIVLRWHL 222
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
I IPKS R++EN I+DF+L ++ + S + R
Sbjct: 223 AHNRIIIPKSQTPKRIKENFDIFDFNLELTDVAEIDSLNKNAR 265
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 169 bits (411), Expect = 9e-41
Identities = 103/281 (36%), Positives = 159/281 (56%), Gaps = 25/281 (8%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P L L++G IP G GT+ LKG + ++ A+ GYR +D+A Y E VG
Sbjct: 23 PDLILHDGHSIPALGFGTYT------LKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVG 76
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
A+++ G++ R+++F+T+KL +H + + + +SL + DY+DLYLIHWP
Sbjct: 77 AAVRQS---GLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP--- 129
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
+ Q Y+E WQA+ D +G +SIGVSNF + +E L+ E GV P + QVE++
Sbjct: 130 ----NPQQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVINQVELHP 185
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
Q Y ++Q I+ +A++P G A A DD L IAQ+ +TV Q+VL
Sbjct: 186 YFNQAEQRAYDESQQIITMAWSPLGR-------AKA-ILDDAVLKQIAQETSRTVVQVVL 237
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
R+ V++GVIPIPK+ N I+DFSL+ D++Q + +
Sbjct: 238 RWQVQMGVIPIPKAASDQNQMANQAIFDFSLSDDQVQRINA 278
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 169 bits (411), Expect = 9e-41
Identities = 101/282 (35%), Positives = 158/282 (56%), Gaps = 21/282 (7%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LN G +IP G GT+ +NE E +V A+D GYRH+D A Y ED+VG AI+
Sbjct: 17 LNTGAKIPAVGFGTF----ANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIR 72
Query: 90 KKIAEGV-VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
+A V R+DLF+ TK+WN H+ E V + + S +NL +DY+DL+L+HWPIA N
Sbjct: 73 DFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKN 132
Query: 149 ASIS-----QTDYV----------ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGG 193
A + YV TW+AM ++++ G+ K+IGVSN+ I L++L
Sbjct: 133 ADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFAR 192
Query: 194 VTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIA 253
+ P+V Q+EI+ L L+++C I+ AY+P G+ N+ P+ D+ L A+A
Sbjct: 193 IKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSPLGSQ-NQVPTTGERVRDNPTLNAVA 251
Query: 254 QKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFS 295
+ ++ Q++L + ++ G + +PKS R+E N I + S
Sbjct: 252 DRRGSSLAQVLLAWGLKRGYVVLPKSSTPSRIESNFIIPELS 293
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 169 bits (411), Expect = 9e-41
Identities = 103/285 (36%), Positives = 154/285 (54%), Gaps = 25/285 (8%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P + LN+G+ G+GT+ L+GDE ++ AID+GYR +DTA Y E +VG
Sbjct: 5 PTISLNDGRPFAEPGLGTY------NLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVG 58
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
RA++ V R++L V +K+ H + + ++R SL L LD +DL LIHWP
Sbjct: 59 RAVRASS----VDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP--- 111
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
N S+ + +++TW+ M D GL +SIGVSNF L+ L E GVTP+V QVE++
Sbjct: 112 --NPSVGR--WLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHP 167
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
Q AL + GI +++P + + +Q L +A Y T Q+VL
Sbjct: 168 YFPQAALRAFHDEHGIRTESWSPL--------ARRSELLTEQLLQELAVVYGVTPTQVVL 219
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
R+ V+LG PIPKS DR EN ++ F+LT D++ + + G
Sbjct: 220 RWHVQLGSTPIPKSADPDRQRENADVFGFALTADQVDAISGLERG 264
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 169 bits (410), Expect = 1e-40
Identities = 104/281 (37%), Positives = 158/281 (56%), Gaps = 29/281 (10%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
L LNN +IP FG GT+ E+ D+ +++V A + GYR IDTA Y E QVG A
Sbjct: 4 LTLNNDVKIPIFGFGTY------EISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEA 57
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
+K A G+ R+++F+TTK ++ + L +SL+ + LDY DL LIHWP+ HD
Sbjct: 58 VK---ASGL-NRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMG-HD 110
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
++TW A+ G T++IG+SNFN +Q L + V P V Q+E +L L
Sbjct: 111 ---------IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIETHLFL 161
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
QQ + ++ + + IV +Y+P GN S P L I++KY K+ Q++LRY
Sbjct: 162 QQWKMHEFLEKENIVHESYSPLGNGQQNLISNPV-------LKEISEKYGKSPIQVILRY 214
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
LV+ V+ IP+S + ++ NI I+DF L D+++ L+ D
Sbjct: 215 LVQNDVVTIPRSTNPAHIKSNIDIFDFELDNDDLKRLRVLD 255
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 168 bits (409), Expect = 2e-40
Identities = 100/284 (35%), Positives = 168/284 (59%), Gaps = 18/284 (6%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSV-EWAIDAGYRHIDTAAIYSTEDQVGR 86
L+LNNG ++P GIGT+ +++G EV K V + + G+R IDTA +Y E+ +G
Sbjct: 26 LRLNNGYDMPLVGIGTY------KVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIGL 79
Query: 87 AIKKKIAEGVVKREDLFVTTKLW-NTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA- 144
A+K+ + + +KRED+F+T+KL + N + + ++ SLK LD Y+DLYLIHWP A
Sbjct: 80 ALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGAS 139
Query: 145 -LHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSE-GGVTPSVLQVE 202
+ +N+ + V TW + ++ +GL +SIGVSN+ + LE L GV P V QVE
Sbjct: 140 RILENSPDNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCSGVKPDVNQVE 199
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQ 262
+ + +Q L+++C QGI V AY+ G S +D + IA + + +
Sbjct: 200 CHPHFRQDELIEFCTKQGIHVQAYSSLGT------SDTTNLLEDPVVKKIASELNVSPAR 253
Query: 263 IVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
++L++ ++ G+ IPK++ D +++NI++ DF ++ D++ LL S
Sbjct: 254 VLLKWALQRGLGIIPKAIKSDHIKDNIKL-DFEISKDQMTLLLS 296
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 168 bits (409), Expect = 2e-40
Identities = 106/291 (36%), Positives = 156/291 (53%), Gaps = 27/291 (9%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L +G +IPG G+GTW + ++ + +V+ A+ GYRHID AAIY ED+VG IK
Sbjct: 18 LADGSKIPGLGLGTWRS------EPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK 71
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL---- 145
E V R+D++VT+KLW H EAV AL K+LK+L LDY+D YLIHWP++
Sbjct: 72 ----ESGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGE 127
Query: 146 -------HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
N + ETW+AM +L G + IG+SNFN LER+ V P+V
Sbjct: 128 DKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAV 187
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYK- 257
Q+E++ L Q ++ K GI V AY+PFGN N + P+ + + K K
Sbjct: 188 HQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGNQ-NTIYESKIPKLIEHETIQKIAKSKG 246
Query: 258 --KTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
T I + + + G IPKS+++ R++ N + LT +++ + S
Sbjct: 247 EGVTGATIAVSWAITRGTSVIPKSVNEQRIKSNFKY--IPLTKEDMDEINS 295
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 168 bits (408), Expect = 2e-40
Identities = 93/286 (32%), Positives = 157/286 (54%), Gaps = 25/286 (8%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
L P +KLNNG IP G+G W + + E Q+ V+ AI Y IDTA Y E
Sbjct: 9 LQPKIKLNNGHLIPQLGLGVWKASLA------ETQQMVKEAIMNDYVLIDTAKQYGNEAA 62
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKK-EAVLPALRKSLKNLDLDYVDLYLIHWP 142
VG+ I+ KR+ +F+TTK++N + + + A+ + LK L +YVDL L+HWP
Sbjct: 63 VGQGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWP 122
Query: 143 IALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVE 202
+ Y E+W+A+ D+ G K+IGV NFN++++ L + P++ Q+E
Sbjct: 123 V---------NDKYNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIE 173
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQ 262
N + QP ++ +C+ I + A++P GN + + IA +++K+ Q
Sbjct: 174 FNPLIHQPKIVKFCRENDIQLEAWSPLGN---------GRLLSNDVIKQIADEHQKSPAQ 224
Query: 263 IVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
++LR+ ++ G I + K+ H R++EN +I+DF+L+PDE++ + D
Sbjct: 225 VILRWEIQQGFIVLTKTTHPQRMKENAEIFDFTLSPDEMKQIDKLD 270
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 168 bits (408), Expect = 2e-40
Identities = 104/274 (37%), Positives = 149/274 (54%), Gaps = 26/274 (9%)
Query: 33 GKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKI 92
G +P G+GTW +L G +++VE A+ GYRHIDTA Y E QVG +
Sbjct: 8 GTSVPALGLGTW------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGMDA-- 59
Query: 93 AEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASIS 152
V RED+F+TTKL +N + +V + R+SL L DY+DL LIHWP AS+S
Sbjct: 60 --AAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWPNTPW-MASLS 116
Query: 153 QTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPAL 212
ET AM DV+ +GL + IGVSNF+ L+R + QV+ + Q L
Sbjct: 117 -----ETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWDQRKL 171
Query: 213 LDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVEL- 271
LDYC+ +++ AY+P A DD LV I KY K+ Q+ LR+LV+
Sbjct: 172 LDYCRIHDVLLTAYSPL---------ARGGVLDDPALVQIGNKYGKSPAQVALRWLVQQD 222
Query: 272 GVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLK 305
GV IPK+ ++ +E N+ ++DF LT E++ ++
Sbjct: 223 GVAAIPKASSREHLEANLAVFDFELTDAEMERIR 256
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 167 bits (406), Expect = 3e-40
Identities = 101/285 (35%), Positives = 157/285 (55%), Gaps = 26/285 (9%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG ++P G G + ++L + Q+ VE ++ GYR +DTA IY E VG AIK
Sbjct: 7 LNNGIKMPRLGFGVY---QIDDLA--QAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAIK 61
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
V RED+F+T+K+W ++ + L A S+K L LDY+DLYLIH P
Sbjct: 62 ----HSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPY------ 111
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
DY TW+A+ + +G ++IGVS+F ++L L + V P+V Q+E N+ Q+
Sbjct: 112 ----NDYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWNQE 167
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
Y + +G+ A+ PF N + P L IA+K+ KT Q++LR+ +
Sbjct: 168 WKSQQYMEKEGVQPEAWAPFAEGANHIFTNPL-------LEEIAEKHHKTTAQVMLRWFL 220
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTL 314
+ + IPKS+HK R+ EN ++DF L D+++ +K+ D G+ L
Sbjct: 221 QRNYVVIPKSVHKKRLAENYDVFDFELDADDMKKIKTLDQGHSIL 265
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 167 bits (405), Expect = 5e-40
Identities = 94/256 (36%), Positives = 147/256 (57%), Gaps = 12/256 (4%)
Query: 55 DEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVV-KREDLFVTTKLWNTNH 113
+E ++ AI+ GYRH DTA +Y+TE V A+ + + G+V R D+FVT+KLW ++
Sbjct: 34 EETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVASRADVFVTSKLWCSDL 93
Query: 114 KKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA---------SISQTDYVETWQAMT 164
V+PA R++L+NL +DYVDL L+HWP + + D W+ M
Sbjct: 94 HAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGME 153
Query: 165 DVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVV 224
+ GL ++IGVSNF+ ++LE+L S V P+ QVE+N QQ L + C+ +G+ +
Sbjct: 154 ECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQLC 213
Query: 225 AYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDR 284
Y+P G P A D L IAQ KT+ QI LR++ E G + + K+ +++R
Sbjct: 214 GYSPLG--AKGTPWGSAAVMDSGVLHDIAQTKGKTLAQICLRWMYEQGDVLLVKTYNENR 271
Query: 285 VEENIQIYDFSLTPDE 300
++EN+ I+D+ LT +E
Sbjct: 272 MKENLDIFDWELTEEE 287
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 166 bits (404), Expect = 6e-40
Identities = 96/280 (34%), Positives = 152/280 (54%), Gaps = 19/280 (6%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P L +G +P G+GT+ S+ EV SV A + GYRH D AA+YS E ++G
Sbjct: 17 PQRTLASGARMPAIGMGTF---GSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIG 73
Query: 86 RAIKKKIAEGV-VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA 144
++ + ++REDL++T+KLWN H + V+PA KSL++L LDY+DLYLIHWP
Sbjct: 74 ATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFP 133
Query: 145 -LH----DNASIS-------QTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEG 192
H D +S S ++++TW+ + + ++GL + IG SN I +L+ L +
Sbjct: 134 NFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQLLLRDA 193
Query: 193 GVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRA---DDQRL 249
V P+V ++E++ + QQPAL DY + + IV V Y P G+ + A +D +
Sbjct: 194 RVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCPLGSPGRPERDRTAEDTSPLEDPVI 253
Query: 250 VAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENI 289
IA + + L++ V+ G PIP S + + N+
Sbjct: 254 QRIAAAHGMHPAAVCLKWAVQRGQTPIPFSTKRRNIHANL 293
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 166 bits (404), Expect = 6e-40
Identities = 102/280 (36%), Positives = 152/280 (54%), Gaps = 27/280 (9%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L+NG IP G GT+ GD + AI GYRH DTA+ Y TE +G+A+
Sbjct: 10 LSNGLSIPAVGFGTYK-------TGDGDSAVLSNAIAQGYRHFDTASFYGTETALGQAV- 61
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP---IALH 146
AE + RED F+T+KLW T +A L A +L+ L DY+DLYLIHWP + L
Sbjct: 62 ---AESDIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDLELE 118
Query: 147 DNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 206
D A + + ETW+A+ + GL ++IGVSNF LE + + V P V Q+E +
Sbjct: 119 DWAKLDR----ETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFHPG 174
Query: 207 LQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLR 266
Q + +C+ I+V A++P G NR + L +A ++ + QI LR
Sbjct: 175 YTQDEAVAFCQNHSILVEAWSPLGR--NR-------LTGNGVLTRLAAEHGVSPAQICLR 225
Query: 267 YLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
+ ++ GV+P+PKS +R+ EN+ ++ FSLT +E+ L +
Sbjct: 226 FALQRGVLPLPKSSSPERMAENLDLFSFSLTGEEMAALST 265
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 166 bits (404), Expect = 6e-40
Identities = 111/287 (38%), Positives = 153/287 (53%), Gaps = 28/287 (9%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P L LNNG +IP G G + ++ +E Q+ VE A++AGYRHIDTAA Y E VG
Sbjct: 10 PQLTLNNGVKIPQLGFGVF------QVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVG 63
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
AI A G+ RED+F+TTKL N ++ A + S K L +++VDLYLIHWP+
Sbjct: 64 AAIS---ASGI-PREDIFITTKL--RNGEQGNAHEAFQNSRKALGVEFVDLYLIHWPVP- 116
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
SQ Y E W+AM + ++IGVSNF + L+ L V P+V QVEI+
Sbjct: 117 ------SQGLYTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQVEIHP 170
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
QQ L C+ GI V AY+P G + +A + +A KY T QIVL
Sbjct: 171 TFQQQELAAKCRELGIAVEAYSPLGQGADLNATA---------VKDLAGKYDATPAQIVL 221
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
+ + G I IPKS R+ EN+ L+P E+ + + ++G R
Sbjct: 222 AWHLAQGTIVIPKSADSKRMRENLGAVAVELSPAELSEISALESGAR 268
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 166 bits (404), Expect = 6e-40
Identities = 112/304 (36%), Positives = 164/304 (53%), Gaps = 40/304 (13%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEW---AIDAGYRHIDTAAIYSTED 82
P + LN G +P +G W G L +E ++ EW A+ +GYRHIDTA IY TE
Sbjct: 5 PPIVLNTGARMPALALGGWAG-----LTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEK 59
Query: 83 QVGRAIKKKIAEGVVKREDLFVTTKL-WNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHW 141
VG AI+ E + RE+LF+TTKL WN +H + V + +KSL+NL +Y+DLYL+H+
Sbjct: 60 SVGNAIR----ESGIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHF 112
Query: 142 P-IALHDNAS------------ISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERL 188
P +D + ++ + W + +L+ G K+IGVSN++I+ LE L
Sbjct: 113 PQRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEEL 172
Query: 189 KSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQR 248
V P+V QVE++ L Q LL YCK +GI V AYTP G D
Sbjct: 173 LKTAKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTPTGY---------QTVLTDPT 223
Query: 249 LVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
+V +A KY + QIVL + + GV PKS ++ R +EN+ + F L P+++ + + D
Sbjct: 224 IVELAGKYGVSPAQIVLAWHLSRGVAAAPKSANESRQKENLNL-PF-LQPEDVAKISALD 281
Query: 309 NGYR 312
G R
Sbjct: 282 RGQR 285
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 165 bits (401), Expect = 1e-39
Identities = 102/280 (36%), Positives = 154/280 (55%), Gaps = 24/280 (8%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
+L+NG IP G GT+L + +V +++ A+DAGYRH+D A IY E VG AI
Sbjct: 5 QLSNGVTIPMLGFGTYL------IDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEAI 58
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
K A G+ R DLF+T+K+WN + + L A ++L +L LDY+DLYLIHWP D+
Sbjct: 59 K---ASGI-DRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP--NEDD 112
Query: 149 ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQ 208
++ ++TW+ + + Q ++IGVSNF+ QL+++ V P + Q+E +
Sbjct: 113 FELT----LDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIERHPYKV 168
Query: 209 QPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYL 268
Q L + IV Y+P G+ +D + +A+KY K+ QIVLR+
Sbjct: 169 QADLGQFDTDNDIVNEGYSPIGH--------GHLILEDPVITKLAEKYGKSPAQIVLRWQ 220
Query: 269 VELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
++ G + PKS RV+EN +I FSLT DEI + D
Sbjct: 221 IDTGFVVFPKSSKPARVKENFEISGFSLTADEIAEINGLD 260
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 165 bits (400), Expect = 2e-39
Identities = 103/279 (36%), Positives = 151/279 (54%), Gaps = 22/279 (7%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L +G E+P G G + + KG Q ++ AI GYR IDTAA Y E +VG AI
Sbjct: 6 LASGIEMPLLGFGVF----QVQEKGAAKQAVLD-AIKTGYRLIDTAASYGNEREVGEAIL 60
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
+ I +G+VKRE+LFVT+K+W + + A++ SL+ L+LDY+DLYLIH P
Sbjct: 61 EAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP------- 113
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
D W+AM G K+IGVSNF+I QL L + P + Q+E+N Q
Sbjct: 114 ---YNDVFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQN 170
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
+ Y G+ V A+ PF N S + L IA K+ K++ QIVLR+L
Sbjct: 171 KKDITYFSQYGVQVEAWAPFAEGKNDLFS-------NILLRKIADKHHKSIAQIVLRWLT 223
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
+ +I + KS+ +R+ +N+ I+DF LT E+ +++ D
Sbjct: 224 QRNIIVVAKSVKPERMAQNLDIFDFKLTHQELAEIETLD 262
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 164 bits (399), Expect = 2e-39
Identities = 103/285 (36%), Positives = 153/285 (53%), Gaps = 27/285 (9%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KL +G+++P G GT+L N +Q + W DAGYR DTA +Y ED +G AI
Sbjct: 11 KLADGRQMPVMGFGTYL-LNDQPTMNTAIQTA--W--DAGYRMFDTAMLYRNEDILGPAI 65
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
++ + RE LF+T+K+ + + A+ SLK L DY+DL LIHWP+ H
Sbjct: 66 QQL----GLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPVREH-- 119
Query: 149 ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQ 208
+ +TW+A+ + G KSIGVSN+ I LE L ++ P V QVE + L
Sbjct: 120 -------FFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHPYLN 172
Query: 209 QPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYL 268
Q AL DY + IV A++P G DD L +A + K+V Q++LR+
Sbjct: 173 QQALADYDQEHDIVTEAWSPLGRRVV---------LDDPMLAKMAAHHNKSVAQVILRWE 223
Query: 269 VELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
++ ++ IPKS H +R++EN I+DFSL DE+ ++ + RT
Sbjct: 224 LQHQLVTIPKSTHPERIQENANIFDFSLDIDEMTMIDLLNKNERT 268
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 164 bits (399), Expect = 2e-39
Identities = 105/288 (36%), Positives = 157/288 (54%), Gaps = 39/288 (13%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
LKLN G+ IP G+GTW K +E K+V A+ AGYRHID AA+Y E +VG+A
Sbjct: 11 LKLNTGQTIPQVGLGTWRS------KENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGKA 64
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH- 146
I+ + V R ++F+TTKLW T+ + AL +SL+ L LDYV LYL+HWP+ L
Sbjct: 65 IQ----DSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVPLRT 118
Query: 147 DNASIS-----------------QTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLK 189
+N + ++++TW+ M +L G TK+IGVSNF++ L+ L
Sbjct: 119 ENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLL 178
Query: 190 S--EGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQ 247
+ VTP+V QVE + L Q L+ YC +GIV+ AY+P G AP D
Sbjct: 179 AAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYSPLG-------GENAPILSDP 231
Query: 248 RLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFS 295
+ IA+ +V+ + V+ G++ +PKS+ R+ N+++ S
Sbjct: 232 TVQEIAKANGVEAGHVVISWAVQKGLVTLPKSVTPSRIVGNLKVLTLS 279
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 164 bits (399), Expect = 2e-39
Identities = 111/321 (34%), Positives = 167/321 (52%), Gaps = 31/321 (9%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
L + LN+G +IP G GTW GD V + A+ AGYRH+D A IY + +
Sbjct: 3 LGKKVTLNSGAQIPQLGFGTWQSAPGQV--GDAVYE----ALKAGYRHLDLATIYQNQRE 56
Query: 84 VGRAIKKKIAEGV-VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP 142
V IK+ + +KRED+F+T+KLWN+ H V AL + L L+LDY+DLYL+HWP
Sbjct: 57 VAEGIKRAYKDVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWP 116
Query: 143 IA---------LHDNASISQTD--------YVETWQAMTDVLNQGLTKSIGVSNFNIQQL 185
++ L ++S+ D V+TW+AMT L + +++GVSN I L
Sbjct: 117 VSFTTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQ-LPKSKARTVGVSNHMIPHL 175
Query: 186 ERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRAD 245
E + + GV P+V Q+E + LQ L++YC+ +GI V AY+ FGN P R +
Sbjct: 176 EAIINATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAFGNNGFGVPLL-VTRPE 234
Query: 246 DQRLVAIAQKYKKTV---PQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQ 302
+ + A K T Q++L + G IPKS+ R+ EN + + LTP+EI
Sbjct: 235 VKEVAESASKRLGTTVTPAQVILAWSQVGGHSVIPKSVTPSRIHENFK--EVELTPEEIA 292
Query: 303 LLKSFDNGYRTLSPLFWAHSP 323
+ R + + A++P
Sbjct: 293 KVSELGKDRRRYNTPYVANTP 313
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 164 bits (398), Expect = 3e-39
Identities = 101/283 (35%), Positives = 157/283 (55%), Gaps = 29/283 (10%)
Query: 31 NNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKK 90
N+ +IP G G + G VQ S+ A++AGYRHIDTA Y E +VG A++K
Sbjct: 15 NSDVKIPRLGFGVYRSPT-----GQCVQSSLR-ALEAGYRHIDTAQFYGNEKEVGEALRK 68
Query: 91 KIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDL--DYVDLYLIHWPIALHDN 148
+ R D+FVTTK+ + EA L +S++ + YVDL+LIH +
Sbjct: 69 C----GIPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIH-------S 117
Query: 149 ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV-TPSVLQVEINLNL 207
+S E WQA+ +L +G T+SIGVSNF ++ +E +K+ V P V Q+E++
Sbjct: 118 SSSGSAGRKELWQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWC 177
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
QQ + YCK GIVV AY+P + +A+D LV +A+KY++T QI++RY
Sbjct: 178 QQRVIEAYCKRNGIVVEAYSPLVRNY---------KANDPTLVDVAKKYERTTAQILIRY 228
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
++ G +P+PKS +R+ N ++DF + +++ +L D G
Sbjct: 229 ALQKGWVPLPKSDTPERIVANANVFDFEIGEEDLAVLNGLDQG 271
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 163 bits (397), Expect = 4e-39
Identities = 95/281 (33%), Positives = 151/281 (53%), Gaps = 19/281 (6%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
L + +L NG IP GTW G+ ++V A+ AGYRHIDTA Y E
Sbjct: 4 LTTMYQLANGVNIPKVAFGTWQIPG-----GEATYQAVRAALAAGYRHIDTALAYQNEAS 58
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
VG+AI+ + + RE +FVTTKL + L +SLKNL LDYVDLYL+H P
Sbjct: 59 VGQAIR----DSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPW 114
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
+ ++ WQAM + G K+IGVSNF ++ L+ + ++ + P V Q++
Sbjct: 115 PWGQVGRVYDEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQY 174
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
L +P + + + ++V AY+P A D+ ++ A A KY +V Q+
Sbjct: 175 YLGFTEPKITKFSEEHAMLVEAYSPL---------ATGGVLDNPQVQAYADKYGVSVAQL 225
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
LR++++ GV+P+PK+++ +E N Q+ DF+++ ++Q L
Sbjct: 226 ALRFVLQNGVLPLPKAVNPAHIEANTQL-DFAISVADMQAL 265
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 163 bits (397), Expect = 4e-39
Identities = 94/291 (32%), Positives = 160/291 (54%), Gaps = 30/291 (10%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P L LN+G++IP G GTW +++ ++ ++V AID GY IDTAAIY E VG
Sbjct: 5 PTLNLNDGRQIPQLGFGTW------QMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG 58
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
+ GV + D+F+ TK+WN + + L A K L+ L ++VD+ LIHWP
Sbjct: 59 K--------GVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCPE 110
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
D +V+TW+A+ ++ + G KSIGVSNF + L+R+ E GVTP++ Q+E++
Sbjct: 111 KDQ-------FVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIELHP 163
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
+ QQ + + GIV +++P G ++ + AIA++ + ++L
Sbjct: 164 SFQQRDMRKVHEDLGIVTQSWSPLGQ---------GKGMSNEVIEAIAEETGQPETAVIL 214
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSP 316
R+ ++ G+ PIPK+ +D +E N + F L+ +++ + + D+ + P
Sbjct: 215 RWHIQHGLCPIPKASSRDHIEANFKALSFELSDEQMGRIDALDDPKGRMGP 265
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 163 bits (397), Expect = 4e-39
Identities = 107/302 (35%), Positives = 160/302 (52%), Gaps = 35/302 (11%)
Query: 25 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQV 84
+P L LNNG I G G + ++ + V A++AGYRH DTAA+Y E V
Sbjct: 4 SPRLSLNNGVLIDQLGFGLY------KVPPADAAGLVTMALEAGYRHFDTAAMYGNETGV 57
Query: 85 GRAIKKKI-------------AEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDL 131
G+AI A + REDLFVTTK+WN +H +A + A S+ NL +
Sbjct: 58 GKAIGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGM 117
Query: 132 DYVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSE 191
+YVDLYLIHWP A + + E+++AM + +G ++IGVSNF LE L
Sbjct: 118 EYVDLYLIHWPCA-------RRGLFTESYRAMETLYREGRIRAIGVSNFQPAHLEHLLET 170
Query: 192 GGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVA 251
V P+V Q+E++ LQQ L GI A++P G Q A D ++
Sbjct: 171 AEVVPAVNQIELHPWLQQDELRQLHDRLGIRTEAWSPLG---RGQVLA------DPVVLE 221
Query: 252 IAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGY 311
+A ++++ QI+LR+ V+LG + IPK+ R+ EN+ ++ F+L P E+ L + + G+
Sbjct: 222 LAAAHRRSAAQIILRWHVQLGNVVIPKASSYARIRENLDVFGFTLDPAEMAALAALERGH 281
Query: 312 RT 313
RT
Sbjct: 282 RT 283
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 163 bits (395), Expect = 7e-39
Identities = 107/312 (34%), Positives = 163/312 (52%), Gaps = 18/312 (5%)
Query: 27 VLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGR 86
V +L G+ IP G+GT+ E +V AI GYRH DTA IY +E+ +G
Sbjct: 5 VARLRCGETIPLLGMGTYCPQKDRE----STISAVHQAIKIGYRHFDTAKIYGSEEALGT 60
Query: 87 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH 146
A+ + I+ G V+R+DLFVT+KLW+++H + AL ++LK + LDY+D YL+HWPI L
Sbjct: 61 ALGQAISYGTVQRDDLFVTSKLWSSDHHDP--ISALIQTLKTMGLDYLDNYLVHWPIKLK 118
Query: 147 DNAS--ISQTD-------YVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPS 197
S I + D ETWQ M L GL +SIGVSNF+ +++ L V+PS
Sbjct: 119 PGVSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPS 178
Query: 198 VLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYK 257
V QVE++ +Q L C+ I V Y+P G N S + + +IA K+
Sbjct: 179 VNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGGPGNCWGSTAV--IEHPIIKSIALKHN 236
Query: 258 KTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPL 317
T Q+ LR+ + G I KS + R+ EN + + L ++ L+ + ++ +
Sbjct: 237 ATPAQVALRWGMSKGASVIVKSFNGARMIENKRALEIKLDDQDLSLIDHLEE-WKIMRGD 295
Query: 318 FWAHSPYFPFES 329
F + P++S
Sbjct: 296 FLVNQTTSPYKS 307
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 163 bits (395), Expect = 7e-39
Identities = 99/275 (36%), Positives = 152/275 (55%), Gaps = 26/275 (9%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L NG IP G+G +L L + VE A+D GYR IDTA Y E + G IK
Sbjct: 12 LLNGSRIPACGVGVYL------LPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGIK 65
Query: 90 KKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPALRKSLKNLD-LDYVDLYLIHWPIALHD 147
+ + KRED+ TTK+ N N + +L++SL + L+Y+DL LIH P++
Sbjct: 66 AWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLS--- 122
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVT--PSVLQVEINL 205
+ +ETW+A+ + ++ G+ KSIGVSNF ++ L G+ P V Q+E++
Sbjct: 123 ----DKKTRIETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIELSP 178
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
L + L+DYC+ GIV+ AY P + +D LV +A+KY KT Q++L
Sbjct: 179 WLMRKDLVDYCQNLGIVLEAYCPL---------TTGAKLNDPTLVKLAKKYNKTPAQVLL 229
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDE 300
R+ ++ GV+ IPKSL +R+ +N ++DF LT ++
Sbjct: 230 RWNIDRGVVVIPKSLKPERLPQNFDLFDFKLTDED 264
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 161 bits (392), Expect = 2e-38
Identities = 106/314 (33%), Positives = 167/314 (53%), Gaps = 42/314 (13%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LN +IP G+GTW + GD ++V+ A+ GYR ID A +Y E +VG A+
Sbjct: 14 LNTKAKIPAIGLGTW------QSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALA 67
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP-IALHDN 148
+ G +KRED+F+T+KL+ T + + ++R SLKNL + Y+DLYL+HWP I +
Sbjct: 68 EAF-NGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGD 126
Query: 149 A----SISQTDYVE-------TWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPS 197
A S S D+ + W+AM ++ GL ++IGVSNF +QQ++ L + P+
Sbjct: 127 ATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPA 186
Query: 198 VLQVEINLNLQQPALLDYCKAQGIVVVAYTPFG-----------------------NLFN 234
V QV+++ +Q L+ +C+++GI V A+TP G F
Sbjct: 187 VNQVKLHPFWRQDELVKFCQSKGIHVSAHTPLGVPASGPGPSDSGSGGEDEPGTPRISFR 246
Query: 235 RQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDF 294
R S P + IA ++KKT Q++LR+ ++ G +P SL DR+ +NI I+ +
Sbjct: 247 RSRSVHGPMLKLSVVAEIADRHKKTPEQVILRWGLQRGTSVLPCSLKADRIRKNIDIFSW 306
Query: 295 SLTPDEIQLLKSFD 308
SL+ DE L +
Sbjct: 307 SLSDDECNCLNQIE 320
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 161 bits (391), Expect = 2e-38
Identities = 99/288 (34%), Positives = 160/288 (55%), Gaps = 25/288 (8%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
L LNNG ++P G+GT+ L G QK++ AI+ GYR D+A +Y+ E ++G A
Sbjct: 4 LTLNNGVKMPILGLGTY------SLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAA 57
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
I + +G +KRE+ F+ TKL ++ ++ ++ KSLK L LDY+D LIH P
Sbjct: 58 INAAV-KGGIKREEFFIQTKLLESS-SEDLAKKSIEKSLKTLGLDYIDSLLIHMPY---- 111
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
SQ+ + ++AM QG+ + IG+SNF + V P++ Q E +L L
Sbjct: 112 ----SQSKAM--YRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCETHLLL 165
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
QQ L + K++ ++ +++PF + ++ L +IAQKY KT Q+VLR+
Sbjct: 166 QQKPLREAMKSKKTLLQSWSPF-------IAGKGSILENPTLKSIAQKYNKTPAQVVLRF 218
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLS 315
L+E G+ IPK+ + R++EN+ ++DFSL+ + Q+LK D S
Sbjct: 219 LIEQGISVIPKTSKRARMQENLNVFDFSLSAQDTQILKELDTNKSAFS 266
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 161 bits (391), Expect = 2e-38
Identities = 94/292 (32%), Positives = 154/292 (52%), Gaps = 24/292 (8%)
Query: 19 SPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIY 78
+P++ P L G IP G GT+ ++ ++ +V A++ GYRHIDTA +Y
Sbjct: 10 APASSPIPTFMLPTGSPIPVLGFGTY------KVAPEDTYDAVSRALEVGYRHIDTAQMY 63
Query: 79 STEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYL 138
E +VG A++ A G+ REDLF+TTK+ N+NH+ + ++R+SL++L DYVDL L
Sbjct: 64 GNEAEVGAALE---ASGIA-REDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLL 119
Query: 139 IHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
+HWP+ ++ D W A+ D N G ++IG+SN+ + +E ++ V P V
Sbjct: 120 VHWPL-----PTLYGGDVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHV 174
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKK 258
LQVE + L Y + G+V A++P A D LV I +
Sbjct: 175 LQVESHPFFPNADLRAYAQGLGMVFEAWSPL---------ARGRAVTDPTLVEIGAELGV 225
Query: 259 TVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
Q+ LR+ ++ G + PK+L ++R+ N ++ FSL P++ + + D G
Sbjct: 226 GPTQVTLRWALDRGHVVFPKTLSRERMAANFDVFSFSLDPEQTARIDALDAG 277
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 161 bits (391), Expect = 2e-38
Identities = 101/284 (35%), Positives = 152/284 (53%), Gaps = 26/284 (9%)
Query: 25 APVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQV 84
AP + L NG E+P G+GTW T+ DE K+V AI+ GYR IDTA Y E V
Sbjct: 7 APTVTLANGVEMPQLGLGTWPMTD------DEAAKAVATAIETGYRLIDTAENYKNETGV 60
Query: 85 GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA 144
G+ I+ + V R+++F+TTK+ H + A SL+ L LDY+DL+LIHWP
Sbjct: 61 GQGIR----DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP-- 114
Query: 145 LHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEIN 204
+ Q YVE ++ +T +L+ GL ++IG SNF L L + G V P V Q++++
Sbjct: 115 -----NPDQGTYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGFV-PHVNQIQLD 168
Query: 205 LNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIV 264
+P + A+GIV +++P G D + IA+ + KT QIV
Sbjct: 169 PYHLRPDITAIHAAKGIVTESWSPIGRA--------GEMLADPAITRIAEAHGKTPAQIV 220
Query: 265 LRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
LR+ V+ G +P PKS +R +N+ ++ F+LT ++ L D
Sbjct: 221 LRWQVQSGFVPAPKSADPERQAQNLDVFGFALTESDMAALNGLD 264
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 160 bits (389), Expect = 4e-38
Identities = 101/284 (35%), Positives = 159/284 (55%), Gaps = 22/284 (7%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P+ KLNNG EIP FG+ EV+ +V+ + + YR +D +I+ E + G
Sbjct: 9 PIAKLNNGIEIPVFGLAA-------PQDFFEVE-NVQLVVSSNYRLMD-CSIFENEKRFG 59
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
A+++ I G ++R+DLF+ +K TN V AL +LK L + Y+DLYLI P A
Sbjct: 60 VALQQLIEGGKIRRKDLFLMSKFCCTN-TTNLVKAALLDTLKKLQVAYLDLYLIERPPAC 118
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
D+ + +ETW+AM + ++ LT++IG+SNFN +Q+ER+ + P V Q++ +
Sbjct: 119 KDH------NLIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRPQVNQIQCHP 172
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
L Q L YC GI V++Y+P G N QP + D R+ IA++Y KT +IVL
Sbjct: 173 YLNQAKLRKYCSNNGIAVISYSPLGARNNIQPES-LDVLSDCRIKEIARRYNKTPTEIVL 231
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDN 309
+Y V+LG I I D + E+ +DF L P+++ + +F +
Sbjct: 232 KYNVQLGNIVI-----SDMLIESANFFDFYLAPEDMSYISTFSS 270
Score = 157 bits (381), Expect = 4e-37
Identities = 83/219 (37%), Positives = 131/219 (59%), Gaps = 15/219 (6%)
Query: 124 KSLKNLDLDYVDLYLIHWPIALHDNASI------------SQTDYVETWQAMTDVLNQGL 171
+SLKNL LDY+D+YL+HWP AL + S+ S D+V+TW+AM + + L
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330
Query: 172 TKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGN 231
TKSIG+SNFN Q++RL + P + Q+E + L Q L +C +GI V +Y+P G+
Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLGS 390
Query: 232 LFN--RQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENI 289
++P P +D ++ I KY K+ QI+LRY V+LG + IPKS +++R+ EN+
Sbjct: 391 PARPWQKPGDPYV-INDPKIKEIGNKYGKSPAQILLRYNVQLGNVVIPKSSNRNRLVENM 449
Query: 290 QIYDFSLTPDEIQLLKSFDNGYRTLSPLFWAHSPYFPFE 328
I+DF+L+ D+++ + +FD R P++PF+
Sbjct: 450 SIFDFTLSEDDMKYIGTFDCNGRICPQAEAREHPFYPFK 488
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 160 bits (389), Expect = 4e-38
Identities = 103/280 (36%), Positives = 153/280 (54%), Gaps = 27/280 (9%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG++IP +GTWL N DEV K V A++ GYR DTA Y E VG
Sbjct: 9 LNNGEKIPQIQLGTWLINN------DEVNKVVRQAVNIGYRGFDTAKDYGNESGVG---- 58
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP---IALH 146
K I ++R D+F+TTKL E A+ +L L+Y+DL LIH P I ++
Sbjct: 59 KGIWNSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVN 118
Query: 147 DNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 206
+E W+AM + + G +SIGVSNF + +E + + G +TP+V Q+E+++
Sbjct: 119 RTNDRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEVHIG 178
Query: 207 LQQPALLDYCKAQGIVVVAYTPF--GNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIV 264
L+DYCK GI + AY+P G L N DDQ ++A A+KY T Q++
Sbjct: 179 KVPVELMDYCKKLGIKIEAYSPLSHGKLLN----------DDQ-IIAYAKKYNVTPAQLM 227
Query: 265 LRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
L + ++LG I IPKS + ++EN+ I +F ++ ++I L
Sbjct: 228 LAFDMQLGCIVIPKSDNVTEMKENLNI-NFKISDEDIAKL 266
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 160 bits (389), Expect = 4e-38
Identities = 101/287 (35%), Positives = 155/287 (54%), Gaps = 27/287 (9%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P +KLNNG E+P G+GT+L +K D + V AI G+R IDTA Y E +VG
Sbjct: 30 PTVKLNNGMEMPQLGVGTFL------VK-DNAAERVCHAIKVGFRLIDTAQGYGNEKEVG 82
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
I + G+ +RE LF+TTK+ + V +L KSL +L DY+DL LIHWP+
Sbjct: 83 EGICRS---GIDRRE-LFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWPVKG 138
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
H ETWQ + + +++G +SIGVSNFN L+ L + P V Q+EI
Sbjct: 139 HIK---------ETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVVNQIEIEP 189
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
+ Q ++ Y +GI V A+ P G DD + IA ++ K+ Q++L
Sbjct: 190 YMTQHDVVGYTFRKGIQVEAWGPLG-------QGVTGVLDDPAIGEIAARHGKSAAQVIL 242
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
R+ ++ G++ IP+ + +ENI+I+DF L+P E++++ + R
Sbjct: 243 RWHMQRGLVTIPRCDNDAYTDENIRIFDFELSPSEMEIITGLNRNQR 289
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 160 bits (389), Expect = 4e-38
Identities = 88/212 (41%), Positives = 127/212 (59%), Gaps = 13/212 (6%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KLN G + P G+GTW S L GD V +V+ GYRHID A IY E ++G +
Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVGDAVAAAVK----IGYRHIDCAQIYGNEKEIGAVL 62
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
KK + VVKREDLF+T+KLW T+H + V AL ++LK+L L+YVDLYLIHWP +
Sbjct: 63 KKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKG 122
Query: 149 A------SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVE 202
+ ++ D TW+AM + + G ++IGVSNF+ ++L L V P+V QVE
Sbjct: 123 SVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVE 182
Query: 203 INLNLQQPALLDYCKAQGI-VVVAYTPFGNLF 233
+ + +Q L ++CK++G+ + V+ T N F
Sbjct: 183 CHPSWRQTKLQEFCKSKGVHLSVSITRLTNPF 214
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 160 bits (389), Expect = 4e-38
Identities = 99/285 (34%), Positives = 160/285 (56%), Gaps = 31/285 (10%)
Query: 23 GLAPVLKLNNGKEIPGFGIGTW-LGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTE 81
GL+ + LN+G+++P FG+G + L T ++ +A+ GYR +DTA IY E
Sbjct: 8 GLSSFVTLNDGRKMPLFGLGVFRLETGCEDV--------CLFALKNGYRMLDTADIYQNE 59
Query: 82 DQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHW 141
+VG A++K +KRED++VTTKL + L ++S+K LD+ YVDL+LIH
Sbjct: 60 KEVGSAVRKS----GLKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHT 115
Query: 142 PIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQV 201
P + + + A+ + +GL +S+GVSNF + LE L+ G TP++ Q+
Sbjct: 116 P---------RPGNIIAAYDALLTLKEEGLIRSVGVSNFGVHHLEELRKAGCRTPAINQI 166
Query: 202 EINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVP 261
EIN +Q ++ YC GI V Y P +F + D LV ++++Y KTV
Sbjct: 167 EINPFWRQEEIIKYCNKHGITVEGYAP---VFR------GCKFDHPVLVEMSERYGKTVA 217
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
QI++R+ V+ I IPKS + +R+ EN Q++DF ++ +++ L S
Sbjct: 218 QIMIRWSVQKQYITIPKSSNPERILENAQVFDFVISEKDMKNLVS 262
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 160 bits (388), Expect = 5e-38
Identities = 88/275 (32%), Positives = 147/275 (53%), Gaps = 19/275 (6%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L NG IP G+GTW N G+ +V +A+ GYRHIDTA Y E+ VG+A++
Sbjct: 10 LENGVAIPKIGLGTWQVPN-----GETTYHAVSFALKNGYRHIDTAYAYHNEESVGKAVR 64
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
+ + R D+FVT+KL + L +++ N L+ +DLYLIH P +
Sbjct: 65 ----DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKG 120
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
+ + +E W+AM ++ G ++IGVSNF++ L+ + + P V Q+ + Q
Sbjct: 121 ADYTKENIEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQIRYFIGHTQ 180
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
+ +C+ GI+V AY+P A ++ + IA KY KT+PQ+ + Y +
Sbjct: 181 EDVTAFCQDNGILVEAYSPL---------ATGKILENAEIQKIADKYGKTLPQVCICYCL 231
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
+ GV+P+PKS H+ + +N + DF ++ +++Q L
Sbjct: 232 QKGVLPLPKSTHEAFILQNADV-DFEISSEDMQYL 265
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 159 bits (387), Expect = 7e-38
Identities = 103/296 (34%), Positives = 154/296 (52%), Gaps = 30/296 (10%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG +IP G+GTW + + V+ +V A GYRHIDTA Y E VG A++
Sbjct: 17 LNNGNKIPKLGLGTW------RIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVR 70
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
K +KRE+LF+T+K+ ++ ++ SLK + LD++DL LIH P +
Sbjct: 71 KS----KIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWN--- 123
Query: 150 SISQTDY----VETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
S + DY VE + A+ D G +SIGVSNF + LE + P+ Q+ ++
Sbjct: 124 SFRKGDYFKENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQILCHI 183
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
LLDYCK Q I+ AY+P A D R++ +A+KY + QI +
Sbjct: 184 GNTPFTLLDYCKKQNILAEAYSPI---------AHGELLKDPRVIELAKKYNVSPAQICI 234
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSF---DNGYRTLSPLF 318
RY +ELG++ +PKS + EN Q+ DF+ + ++Q LK D G + P+F
Sbjct: 235 RYTLELGLVSLPKSKTPKYIAENAQV-DFTFSKADLQTLKKLTFKDYGEHSYFPVF 289
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 159 bits (387), Expect = 7e-38
Identities = 107/296 (36%), Positives = 163/296 (55%), Gaps = 37/296 (12%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L+NGK IP G+GT + +ELK + V A+ AGYRHIDTA Y TE+ +G+A+K
Sbjct: 12 LSNGKTIPALGLGTVPPEDPHELK-----EQVITAVKAGYRHIDTAWYYGTEEYIGQALK 66
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH--- 146
+ EG+VKREDLF+TTK+W + + +L KSL +L LDYVDL+L HWP+ LH
Sbjct: 67 QLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLHGDE 124
Query: 147 ----------------DNASISQTDYVETWQAMTDVL-NQGLTKSIGVSNFNIQQLER-L 188
D+ +S Y++ + ++ D++ N KSIGVSN++I +L + L
Sbjct: 125 NGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLRKLL 184
Query: 189 KSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQR 248
+ P V Q+E + L Q L+ YC G+ + AY+P G S AP Q
Sbjct: 185 AAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAYSPVG-------SNGAPVLKLQL 237
Query: 249 LVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
+ +A KY +V +I Y + G +P+S + +R++ I++ +LT +E+ L
Sbjct: 238 INELASKYDVSVNEIANAYHILQGRSVLPRSSNLERIKSIIRLP--NLTTEELNAL 291
>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
clavatus
Length = 283
Score = 159 bits (387), Expect = 7e-38
Identities = 98/283 (34%), Positives = 157/283 (55%), Gaps = 29/283 (10%)
Query: 31 NNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKK 90
N+ IP G G + + +S A+ AGYR+IDTA Y+ E +VG A++
Sbjct: 15 NSSVRIPRLGFGVYRSPTR------QCVQSCLTALQAGYRNIDTAQFYANEQEVGEALR- 67
Query: 91 KIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNL--DLDYVDLYLIHWPIALHDN 148
G+ R D+FVTTK+ + EA L +S++ + + YVDL+LIH +
Sbjct: 68 --TSGI-PRSDVFVTTKILSPAGSPEATYKKLLESVEKIGGENGYVDLFLIH-------S 117
Query: 149 ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV-TPSVLQVEINLNL 207
+S E WQA+ +L +G TKSIGVSNF ++ +E +K+ V P V Q+E++
Sbjct: 118 SSSGSAGRKELWQALEKLLEEGKTKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWC 177
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
QQ + YCK GIVV AY+P + +A+D LV +A+KY KT Q+++RY
Sbjct: 178 QQRVIDAYCKRNGIVVEAYSPLVRNY---------KANDPTLVDLAKKYGKTTAQVLIRY 228
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
++ +P+PKS +R+E N +++DF ++ +++ +L + D G
Sbjct: 229 ALQKHWVPLPKSDTPERIEANTKVFDFEISEEDMAVLNALDQG 271
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 159 bits (386), Expect = 9e-38
Identities = 98/291 (33%), Positives = 163/291 (56%), Gaps = 27/291 (9%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
L +KLNNG + P F G+++ N K + SV A+ GYRHID+A +Y E
Sbjct: 2 LGSFVKLNNGLKCPQFAYGSYM---VNRTKCFD---SVYAALQCGYRHIDSAQMYHNEAD 55
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
GRAI K + E KRED++ T+KL + + K + L ++ S+K L Y+DL+L+H P
Sbjct: 56 CGRAILKFMEETGTKREDIWFTSKLNDLSGYK-STLSSIDASVKACGLGYIDLFLLHSPY 114
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL-ERLKSEGGVTPSVLQVE 202
D +E+W+A+ + +G ++IGVSNF + E L S + P V Q+E
Sbjct: 115 G----------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIE 164
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQ 262
++ Q ++DYC+++GI + AY P + + +++L+AIA KY K+ Q
Sbjct: 165 LHPFCSQQKVVDYCESKGIQLAAYAPLVH---------GEKFGNKQLLAIASKYNKSEAQ 215
Query: 263 IVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
I++RY ++ G I +PKS R++EN ++DF ++ ++++ L + D Y +
Sbjct: 216 IMIRYCLQRGFIVLPKSSTPRRIKENGDVFDFEISKEDMEKLYNLDEDYHS 266
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 159 bits (385), Expect = 1e-37
Identities = 104/286 (36%), Positives = 146/286 (51%), Gaps = 28/286 (9%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGD-EVQKSVEWAIDAGYRHIDTAAIYSTEDQV 84
P + LN+G+ IP G GT+ ++ D ++V+ A+ GYRHIDTA Y ED+V
Sbjct: 5 PTITLNDGRAIPAIGFGTF------QIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEV 58
Query: 85 GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA 144
G+AIK + + R+ ++VT+KLW ++ +A A+ +SL L LDY+DLYLIH P
Sbjct: 59 GQAIK----DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQPYG 114
Query: 145 LHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEIN 204
D WQAM G KSIGVSN ++ + P+V QVE N
Sbjct: 115 ----------DVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQVEFN 164
Query: 205 LNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIV 264
QQ L AQ + + A+ P G Q P +A KY K QI+
Sbjct: 165 PYFQQQPLRQLLAAQDVKLEAWAPLGQ--GNQALFKEPIIQQ-----LAIKYHKDAGQII 217
Query: 265 LRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
LR+ + GVI PKS+H R++ N I+DF LT E+ L++ D G
Sbjct: 218 LRFEHQEGVIVFPKSVHSARIKSNRDIFDFELTSTEMAQLRALDTG 263
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 159 bits (385), Expect = 1e-37
Identities = 104/306 (33%), Positives = 152/306 (49%), Gaps = 30/306 (9%)
Query: 20 PSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYS 79
P A LN IP G GT+L +N D+ + ++ AI AGYRHIDTA+ Y
Sbjct: 32 PMTNTATTFTLNTTTTIPAVGFGTYLISN------DDAKSTISAAIQAGYRHIDTASGYQ 85
Query: 80 TEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTN-------HKKEAVLPALRKSLKNLDLD 132
E VG IK + + R+DLFVT KLW N K L SL L LD
Sbjct: 86 NEKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLD 145
Query: 133 YVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEG 192
YVDLYLIH P +E W+A+ ++ G +SIGVSNFN L +K+ G
Sbjct: 146 YVDLYLIHAP--------YGGDMRLEQWRALLELQANGKARSIGVSNFNESHLNEIKAAG 197
Query: 193 GVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYT---PFGNLFNRQPSAPAPRADDQRL 249
P Q+E++ Q+P LL Y I +AY+ P ++ A A + D+ +
Sbjct: 198 LPMPDANQIELHPWSQKPDLLAYMDQHAIAPIAYSSLVPLSTWRTKEGQASA-KTDEMKA 256
Query: 250 VA-----IAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
+A+KY + Q++LR+ V+ G +PKS++ DR+ +NI ++ FS+ ++ +
Sbjct: 257 AGTTFRDMAEKYGVSEAQLLLRWGVQNGYAVLPKSMNPDRMRQNIDLFSFSIDDTDMAKM 316
Query: 305 KSFDNG 310
+ D G
Sbjct: 317 ATMDQG 322
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 158 bits (384), Expect = 2e-37
Identities = 93/283 (32%), Positives = 153/283 (54%), Gaps = 25/283 (8%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LNNG ++P G G + ++ +E +++V AI+AGYR IDTA +Y E + G+ +
Sbjct: 6 LNNGAQMPQLGFGVF------QIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVN 59
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
+ IA VV RE+LF+TTKLW + EA A+ SLK L DY DL L+H P
Sbjct: 60 EAIANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG----- 114
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFN----IQQLERLKSEGGVTPSVLQVEINL 205
D ++A+ + G KSIG+SNF ++ ++ +K+ P + Q+E +
Sbjct: 115 -----DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQIDQIEFHP 169
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
Q+ G+ + A+ P G N+ + P LV IA K+ K+V Q+VL
Sbjct: 170 YYQEKVARQLHDKYGVQIEAWGPLGRTANKYDTFHQP-----ELVEIAAKHDKSVGQVVL 224
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
R++++ +I + KS++ R+ ENI I++F L D+++ +++ D
Sbjct: 225 RWIMQSNIITVAKSVNPSRMAENIDIFNFELDDDDMKKIETLD 267
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 158 bits (384), Expect = 2e-37
Identities = 93/281 (33%), Positives = 153/281 (54%), Gaps = 21/281 (7%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+KLNNG E+P GIG W L ++ +KSV A+ AGYR IDTA +Y E VGRA
Sbjct: 45 VKLNNGIEMPIIGIGVWT------LTPEQTEKSVGEALKAGYRLIDTARMYRNEQAVGRA 98
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
++ + + RE++F+TTK++ + A A+ + L+ LD DY+DL L+H+P
Sbjct: 99 VR----DSGIPREEIFITTKIYGSGDYANAEA-AINERLRLLDTDYIDLLLLHYP----- 148
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
Q D + W+ M + G ++IG+SN++ + R+ +TP+V+Q E+++
Sbjct: 149 ----DQND-TKAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVHIYN 203
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
Q + + G + A+ P G + D +V++A+KY K+ Q++LR+
Sbjct: 204 QDKQTKAFLRNYGTQMEAWYPLGGRNSYGNGGKDVLFADPTIVSLAKKYAKSPAQVLLRW 263
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
++ G I IP S + + ENI I+DF+L+ DE+ L D
Sbjct: 264 QLQAGNIAIPGSSNPAHIRENIDIFDFALSDDEMATLSRLD 304
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 158 bits (384), Expect = 2e-37
Identities = 93/294 (31%), Positives = 161/294 (54%), Gaps = 16/294 (5%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KLN+G IP G GT+ ++ G+ V +++ A+ AGYR DTA Y E ++G A+
Sbjct: 14 KLNSGYNIPFVGFGTY------KVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEAL 67
Query: 89 KKKIAEGVVKREDLFVTTKLW-NTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH- 146
K + + + R D+F+T+K + + + +EA + +SL++L DY+D+YL+H+P
Sbjct: 68 KILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDS 127
Query: 147 DNASISQTDYVE-TWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
DN ++ +Y + ++ + + G +SIGVSN+ I LE LK+ V P Q+E +
Sbjct: 128 DNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLEYHP 187
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
+ + L YCK + I A F +L +P +D +V +A+K+ +VP ++L
Sbjct: 188 HFARIPLQKYCKEKNIFFQA---FSSLARHEPKL----IEDPVVVELAKKHNTSVPLVLL 240
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFW 319
+ + V +PKS+ R+ EN ++ D +LTP++IQ L + D G + W
Sbjct: 241 AWALRQNVGIVPKSVTPSRIVENFKVIDIALTPEDIQSLTALDRGQHYIRCTGW 294
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 158 bits (384), Expect = 2e-37
Identities = 103/297 (34%), Positives = 153/297 (51%), Gaps = 34/297 (11%)
Query: 21 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 80
S L +KL +G IP G G + + + E + +V+ AID GYRH+DTA Y
Sbjct: 2 SLSLDSTIKLASGNLIPRLGFGVY------QARSKECEDAVKKAIDTGYRHVDTAQAYHN 55
Query: 81 EDQVGRAIKKKIAEGVVKREDLFVTTKLW--NTNHKKEAVLPALRKSLKNLDL-----DY 133
E+ VGRAI+ V R +F+T+K +T + VL +RKSLK +D Y
Sbjct: 56 EENVGRAIRNS----GVPRPSVFLTSKYMPSHTVYSPTEVLDVVRKSLKKVDRCGDDKPY 111
Query: 134 VDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGG 193
+DL LIH P + W+A+T +G K IGVSNF I L+ L
Sbjct: 112 IDLMLIHAPWGGEEGRK-------NNWEALTIAQKEGWVKDIGVSNFGIHHLKALPPP-- 162
Query: 194 VTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIA 253
P+V Q+E++ QQ ++ YC+ GI + AY+P A D++ LV +A
Sbjct: 163 -VPAVNQIELHPFCQQRDIVKYCEEHGIAIEAYSPLVR-------ANKKHYDNEVLVKVA 214
Query: 254 QKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
+KY K V Q++LR+ ++ G IP+PKS+ R+E N +YDF L +++ + D G
Sbjct: 215 KKYGKEVAQVLLRWSLQKGYIPLPKSVTPSRIESNADLYDFKLDQEDMAEIDGLDKG 271
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 158 bits (384), Expect = 2e-37
Identities = 100/297 (33%), Positives = 162/297 (54%), Gaps = 29/297 (9%)
Query: 18 LSPSAGLAPV------LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRH 71
LS +G APV LK+++G IP FG+G + E+ E V+WA++AGYRH
Sbjct: 17 LSEMSGPAPVKSLDARLKMHDGNAIPQFGLGVY------EMNDKETYDCVKWALEAGYRH 70
Query: 72 IDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDL 131
+DTA Y E G+AI + RE++F+T+KL N + ++A + L+ SLK +
Sbjct: 71 VDTAEWYENEAPCGKAIADFLKATGTSREEIFLTSKLKNNSSYEQAFVD-LKGSLKRSGV 129
Query: 132 DYVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSE 191
+Y DLYL+H I W+A+ D +QGL KSIGVSNF + ++ +
Sbjct: 130 EYFDLYLMHSAIG-------GPVIRKNVWKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQ 182
Query: 192 GGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVA 251
P+V QV+++ ++ P +++ C+ I++ A+ P A A R D +V
Sbjct: 183 KVPLPTVNQVDLHPFMRHPEIVEICEQNEILLEAWGPL---------ARAMRFDHPVVVK 233
Query: 252 IAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
IA++ K QI+LR+ ++ G + IPKS+ + R+ N +I+DF L+ +E++ L D
Sbjct: 234 IAKEKGKDAAQIMLRWGIQHGFVVIPKSVSQKRIVSNSKIFDFELSSEEMKELDGLD 290
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 158 bits (383), Expect = 2e-37
Identities = 86/280 (30%), Positives = 156/280 (55%), Gaps = 13/280 (4%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSV-EWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAE 94
+P GIGTW +++ +E+ + V + GYR IDTA +Y+ E ++GR ++K +
Sbjct: 11 MPLIGIGTW------QVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPA 64
Query: 95 GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP-IALHDNASISQ 153
+KRED+++T+KL +N + ++ +SL NL ++Y+DL LIHWP +L ++
Sbjct: 65 NGLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENPANK 124
Query: 154 TDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALL 213
VE+W M +++ +G +S+GVSNF I LE LK + V P+V QVE + + Q L+
Sbjct: 125 KLRVESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQDDLV 184
Query: 214 DYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGV 273
YC I AY+ G+ P+ +++ + +AQKY +P ++L + G+
Sbjct: 185 KYCNENNIHFQAYSSLGS-----PTYRKQLSEEPLIKELAQKYNVEIPVLLLGFAYCQGI 239
Query: 274 IPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
+P++ + + V N ++ ++T ++I L + ++T
Sbjct: 240 SVLPRTTNPEHVATNFKVTKLAITQEDIDRLLALTVEHKT 279
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 158 bits (383), Expect = 2e-37
Identities = 102/291 (35%), Positives = 167/291 (57%), Gaps = 27/291 (9%)
Query: 29 KLNNGKEIPG--FGIGT-WLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
KL+NG +IP FG GT + N+L ++ ++E A+ +G+RHID A IY T ++G
Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGHNDLD-KQLIGTLELALRSGFRHIDGAEIYGTNKEIG 67
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNH-------KKEAVLPALRKSLKNLDLDYVDLYL 138
A+K + R+D+F+T K + NH K + AL+ L++L L+YVDLYL
Sbjct: 68 IALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYL 123
Query: 139 IHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLER-LKSEGGVTPS 197
IH+P + D VE W+ + N+GL ++IGVSNF I+ L+ L + P
Sbjct: 124 IHFPYISEKSHGF---DLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDANTDSIPV 180
Query: 198 VLQVEINLNLQQ--PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQK 255
V Q+E + LQ P +++Y + QGI++ AY P G + +P P D+ L +++K
Sbjct: 181 VNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGRPG-PL----DKVLSKLSEK 235
Query: 256 YKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSL-TPDEIQLLK 305
YK+ QI+LR++++ G++PI + ++R+ + ++I+DF L DE Q+ K
Sbjct: 236 YKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELDKEDEDQITK 286
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 158 bits (383), Expect = 2e-37
Identities = 103/332 (31%), Positives = 172/332 (51%), Gaps = 34/332 (10%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
++ ++ LNNG ++P G+G W ++ + AI GYR D A Y E +
Sbjct: 1 MSSLVTLNNGLKMPLVGLGCW------KIDKKVCANQIYEAIKLGYRLFDGACDYGNEKE 54
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
VG I+K I+EG+V R+D+FV +KLWN H + V AL+K+L ++ LDY+DLY IH+PI
Sbjct: 55 VGEGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPI 114
Query: 144 AL---------------------HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNI 182
A + + + ++T++A+ + +++GL KSIGVSNF
Sbjct: 115 AFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQG 174
Query: 183 QQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNL----FNRQPS 238
++ L + P LQ+E + L Q L+++CK I VVAY+ FG + Q +
Sbjct: 175 SLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLA 234
Query: 239 APAPRADDQRLV-AIAQKYK-KTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQI-YDFS 295
P + ++ ++Q + T Q++LR+ + G+ IPKS K+R+ N++I F+
Sbjct: 235 KTTPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFT 294
Query: 296 LTPDEIQLLKSFDNGYRTLSPLFWAHSPYFPF 327
LT E++ + + + R P W + F
Sbjct: 295 LTEQELKDISALNANIRFNDPWTWLDGKFPTF 326
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 157 bits (382), Expect = 3e-37
Identities = 99/288 (34%), Positives = 156/288 (54%), Gaps = 20/288 (6%)
Query: 26 PVLKLNNGKEIP--GFGIGT-WLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTED 82
P +KLN+ IP G+G GT W ++ E+ ++++ AI GYRH+D A +Y TE
Sbjct: 10 PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69
Query: 83 QVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP 142
++G AIK E + RE+LFVTTK+ TN + A+ +SL+ L L+YVDLYLIH P
Sbjct: 70 ELGVAIK----ESGIPREELFVTTKVI-TNIAD--IPSAIDQSLRKLQLNYVDLYLIHSP 122
Query: 143 IALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVE 202
+ + Q W AM V G K+IGVSN++ LE + P + Q+E
Sbjct: 123 FFAKSDGELQQA-----WAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIE 177
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQ 262
+ LQQ LL + + + I + +Y P + R P P D ++ +A KYK T +
Sbjct: 178 HHPYLQQEELLRFQREKDIKIASYGPLTPIL-RAPGGPV----DPKVSELAAKYKVTEGE 232
Query: 263 IVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
++LR+ ++ G + + S + R++E +Q+ F LTP+E++ + G
Sbjct: 233 VLLRWSIDRGDVAVTTSSKESRLQEFLQVLTFQLTPEEVREISQLGQG 280
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 157 bits (381), Expect = 4e-37
Identities = 96/276 (34%), Positives = 143/276 (51%), Gaps = 28/276 (10%)
Query: 32 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKK 91
NG +IP G GTW +L+ ++ + V A+ GYRHIDTA IY E VG K
Sbjct: 8 NGADIPKLGFGTW------QLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDGWK-- 59
Query: 92 IAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASI 151
+ VKRED F+TTK+W + + ++++SL L DYVDL L+HWP+
Sbjct: 60 --QSGVKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPVP------- 110
Query: 152 SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPA 211
+ ET +AM +V G + IGVSNF + L+ ++ G QVE + L Q A
Sbjct: 111 -EVPIAETMKAMNEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPYLDQNA 169
Query: 212 LLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVEL 271
+L C+A G+ + AY+P A DD+ + IA+ + + QIVLR+L++
Sbjct: 170 VLTACRAAGMAMTAYSPI---------AQGKVFDDEVITEIAKAHNVSPAQIVLRWLIDQ 220
Query: 272 -GVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
VI IP+S ++ N +I D L+ +E + S
Sbjct: 221 DSVIAIPRSSSDKHIKSNFEIADLKLSQEETGRINS 256
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 157 bits (380), Expect = 5e-37
Identities = 98/278 (35%), Positives = 145/278 (52%), Gaps = 27/278 (9%)
Query: 32 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKK 91
NG IP G+GTW EL G + VE A+ GYRHIDTA +Y E +VG ++
Sbjct: 7 NGARIPAIGLGTW------ELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDGVR-- 58
Query: 92 IAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASI 151
A GV +R+D+F+TTK+W + + ++++SL L L VDL L+HWP
Sbjct: 59 -ASGV-RRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPN-------- 108
Query: 152 SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPA 211
S ET A++ GLT+ IGVSNF + +E+ + QVE + L Q
Sbjct: 109 SHVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPYLDQAK 168
Query: 212 LLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVEL 271
+ C G+ +VAY+P A DQ L I + ++KT Q+ LR+LV+
Sbjct: 169 VRAACDQHGLALVAYSPI---------ARGRIKTDQTLAGIGRAHRKTPAQVCLRWLVQQ 219
Query: 272 GVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDN 309
V IP++ +R+ ENI+I+DF L+ DE+ + + N
Sbjct: 220 NVAAIPRTSRIERLSENIEIFDFELSDDEMARIAALAN 257
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 157 bits (380), Expect = 5e-37
Identities = 92/285 (32%), Positives = 157/285 (55%), Gaps = 25/285 (8%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P LKL +G IP G+GTW + DE + +V +A+ +GYR +DTA Y E+ VG
Sbjct: 14 PRLKLPHGHTIPRLGLGTW------PMLEDECETAVRFALQSGYRLVDTAFQYRNEEAVG 67
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
R I+ V R +LF+++K +H + V A +SL+ L LD++D+++ HWP+
Sbjct: 68 RGIRT----AGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWPVP- 122
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
+ YV+ W+ + +L +G K+IGVSNF L+ + GV P V Q++++
Sbjct: 123 ------ALGKYVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQIQLSP 176
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
+L + + GIV A++P G + RA + ++ IAQ+ K+ Q++L
Sbjct: 177 DLARTEPRAVHRLLGIVTEAWSPIGR-------SSGLRA-NPLIIEIAQRLDKSPAQVLL 228
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
R+ V+ ++PIP++ ++EN+ ++DFSLT E+ ++ D G
Sbjct: 229 RWHVQQDIVPIPQASDPLWLKENLSVFDFSLTAGEMASIRKLDRG 273
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 156 bits (378), Expect = 9e-37
Identities = 98/292 (33%), Positives = 162/292 (55%), Gaps = 25/292 (8%)
Query: 18 LSPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAI 77
+S S + + L NG IP G G ++ LK +E V A+D+GYRHIDTAA+
Sbjct: 1 MSESQTESTTVTLTNGMVIPRIGFGAFM------LKYNECYGLVTQALDSGYRHIDTAAV 54
Query: 78 YSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLY 137
Y ED G+AI + VKR D+F+T+KL N + + A+R SL +L Y+DL+
Sbjct: 55 YGNEDICGKAIVDWCEKNNVKRTDIFLTSKLANCS-DYYSTRAAIRSSLHHLG-TYIDLF 112
Query: 138 LIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERL-KSEGGVTP 196
LI P + + +W+AM + ++ G +S+GVSN+ ++ L+ L S P
Sbjct: 113 LIQSPAG-------GKKSRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASNPKFYP 165
Query: 197 SVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKY 256
V Q+E++ L Q ++ YC++ I + AY+P + R +D++LV IA+K
Sbjct: 166 CVNQIELHPFLSQDDIVKYCQSHDIAIEAYSPLTH---------GIRLNDEKLVPIAKKL 216
Query: 257 KKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
+V Q+++R+ ++ G IPI KS K+ + ++ +++F++ D +Q L SFD
Sbjct: 217 NISVAQLLIRWSLQKGYIPIIKSTKKEHMLSDLDVFNFTIPDDVVQELSSFD 268
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 156 bits (378), Expect = 9e-37
Identities = 110/332 (33%), Positives = 178/332 (53%), Gaps = 40/332 (12%)
Query: 7 SFVFVFAAVIHLSPSAGLAPVLKLNNGKEI--PGFGIGTWLGTNSNELKGDEVQKSVEWA 64
S F+ + + L SA P+ + + I P G GTW + ++ + ++V +A
Sbjct: 8 SLAFLLSNINALYLSAEQHPIAPPSQKQSISQPLIGFGTW----NLKVSPENTTEAVAYA 63
Query: 65 IDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNH-KKEAVLPALR 123
I+ GYR ID AA+Y E VGR I++ + +KRED++VT+KLWN +H E V L
Sbjct: 64 IEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKREDIWVTSKLWNDHHGSYENVEKGLN 123
Query: 124 KSLKNLDLDYVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQ 183
++L++L L+Y+DLYLIHWPI N + D+V+T+++M L + +IGVSNF+
Sbjct: 124 QTLQDLGLEYLDLYLIHWPIGFSSNGA-KNLDHVQTYKSMIS-LPKSRVLNIGVSNFSPL 181
Query: 184 QLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGN------------ 231
QL+ + S G + P + Q+E++ LQQ A + KA GI + AY+P GN
Sbjct: 182 QLKNVVSTGTI-PYMHQMELHPYLQQSAWVATHKALGIKMTAYSPLGNTNPTYHSSTSPS 240
Query: 232 --------------LFNRQPSAPAPRA----DDQRLVAIAQKYKKTVPQIVLRYLVELGV 273
LF S+ P+A + L+ IA++ T Q+ L++ + G+
Sbjct: 241 LSSSSSFSWASWTSLFRPSSSSSKPKAPPLLQNPILIDIAEERNCTPAQVALKWNMGRGI 300
Query: 274 IPIPKSLHKDRVEENIQIYDFSLTPDEIQLLK 305
IPKS H++ ++EN+Q + LT ++ L+
Sbjct: 301 SVIPKSSHEEWIKENLQAGECELTHADLTKLR 332
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 155 bits (377), Expect = 1e-36
Identities = 88/249 (35%), Positives = 141/249 (56%), Gaps = 21/249 (8%)
Query: 64 AIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALR 123
A+ AG+RH D A Y E +VG A++ A G + RE++FVTTKLWNTNH+ E V PA
Sbjct: 42 ALAAGFRHFDCAERYRNEREVGEALRAGRAAGNIAREEIFVTTKLWNTNHRPERVEPAFE 101
Query: 124 KSLKNLDLDYVDLYLIHWPIALH---------DNASISQTDYV---ETWQAMTDVLNQGL 171
SL L LDY+DLYLIH P A N S+ + V ETW A+ +++++G
Sbjct: 102 ASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQNGSVIYDEGVTLRETWSALENLVDRGR 161
Query: 172 TKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGN 231
++IG+S+ ++ +L + + P+V+QVE + L + LL++CK GIV++A+ P G+
Sbjct: 162 CRAIGLSDISMDRLAPIYEAARIKPAVVQVESHPYLPETELLEFCKRNGIVLLAFAPLGH 221
Query: 232 LFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQI 291
+P +D + +++++ KT Q++L + V+ G + R +EN
Sbjct: 222 --GMRPGL----LEDPVITSVSERVGKTAAQVLLSWAVQRGTALLTTPRSAARAKEN--- 272
Query: 292 YDFSLTPDE 300
+D S P+E
Sbjct: 273 FDISPLPEE 281
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 155 bits (376), Expect = 2e-36
Identities = 104/310 (33%), Positives = 158/310 (50%), Gaps = 34/310 (10%)
Query: 37 PGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKK--KIAE 94
P G GTW + + VQ +VE A+ GYRHID A +Y E+ +GRA K K A
Sbjct: 5 PRLGFGTW------QAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDAS 58
Query: 95 GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN------ 148
+KRED+++T+KLWN NH+ E V +K++ +L +DY+DL+L+HWP+A N
Sbjct: 59 SGIKREDVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLF 118
Query: 149 -------ASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQV 201
A + + +TW+AM ++ +GL K IGVSN+ + L L + + P V Q+
Sbjct: 119 PKDAEGRAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQI 178
Query: 202 EINLNLQQPALLDYCKAQGIVVVAYTPFGNLF--NRQPSAPAPRA--DDQRLVAIAQKYK 257
EI+ A + +C GI V AY+P G + R PS + + L AIA K
Sbjct: 179 EIHPWHPNDATVKFCLDNGIGVTAYSPMGGSYADPRDPSGTQKNVILECKTLKAIADA-K 237
Query: 258 KTVPQ-IVLRYLVELG----VIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS--FDNG 310
T P + L + V+ IPKS R+E N + + L+ D++ + + +
Sbjct: 238 GTSPHCVALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKR 297
Query: 311 YRTLSP-LFW 319
R P +FW
Sbjct: 298 IRFCDPAIFW 307
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 155 bits (375), Expect = 2e-36
Identities = 92/297 (30%), Positives = 158/297 (53%), Gaps = 17/297 (5%)
Query: 21 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 80
S + V+ L+NG+++P FG+G+ S +EV + A+D GYRHIDTA +Y
Sbjct: 3 SQEIQKVITLSNGQKMPAFGLGS-----SRVQSVEEVTNLIRKALDVGYRHIDTAQMYEN 57
Query: 81 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIH 140
E +G A+K EG KRED+F+ TK + K + L +++ L+ L +DYVDL LIH
Sbjct: 58 EQFIGAALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIH 115
Query: 141 WPIAL--HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
P+A D + + W ++ + GL K +GVSNFN Q + L + + P V
Sbjct: 116 VPLAAPSDDYQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLV 175
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKK 258
Q+E+++ QQ L+++ K I VA++P +N ++ L IAQK
Sbjct: 176 NQIELHVFNQQKNLVEFLKKVNIYPVAFSPMAK-YNEV-------VKNETLNQIAQKQNA 227
Query: 259 TVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLS 315
+V Q+++ ++ V+ IP++ +R++ N + ++IQ L++ ++ R ++
Sbjct: 228 SVAQVMIAFMYHQDVVVIPRTAKIERLQHNFDAQKLQFSEEDIQTLRNLNSNTRVVN 284
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 155 bits (375), Expect = 2e-36
Identities = 93/288 (32%), Positives = 161/288 (55%), Gaps = 19/288 (6%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDE-VQKSVEWAIDAGYRHIDTAAIYSTEDQV 84
P + LNN ++P G+GT+ L+G E +V+ A+ AGYR DTAA+Y E +
Sbjct: 6 PSVLLNNDIQMPLLGLGTF------RLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHL 59
Query: 85 GRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP-- 142
G A++ + + + RED+F+T+KL + +A +KSL+ L L Y+DLYLIHWP
Sbjct: 60 GHALRCLLPKHGLSREDVFITSKLGPKDQGSKA-RNGCQKSLEQLGLGYIDLYLIHWPGT 118
Query: 143 IALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVE 202
L + + ++W+ + + ++G ++IGVSN+ ++ ++ L V P+VLQVE
Sbjct: 119 QGLPVGDKRNPENRAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQVE 178
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQ 262
+ L Q L CK +G+ AY+ G S P ++ IA++ +T Q
Sbjct: 179 FHPKLLQNDLRGLCKIRGVCFQAYSSLGT--GLLLSNPV-------VLEIAKECGRTPAQ 229
Query: 263 IVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
++LR+ V+ + +PKS +RV+EN +++DF ++ ++++ L + D G
Sbjct: 230 VLLRWAVQQSIAVLPKSSQPERVKENGRLFDFEISEEDMERLSALDCG 277
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 155 bits (375), Expect = 2e-36
Identities = 93/279 (33%), Positives = 154/279 (55%), Gaps = 25/279 (8%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P ++L+ G +P G+GTW LKG+E + +V AI+ GYR +DTA Y E+ VG
Sbjct: 9 PTVELSGGTRMPMLGMGTW------PLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVG 62
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
+A++ E R ++FVTTK H ++ V AL SL+ L LDYVDL+L+HWP+
Sbjct: 63 KAVR----EAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPMP- 117
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
+ YV+ ++ M ++ QGL K+IGVSNF + L+ L +E G+TP V Q++++
Sbjct: 118 ------GEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITE-GMTPEVNQIQLDP 170
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
+ + + D+ IV A++P G + +APA ++ A+K+ T VL
Sbjct: 171 SRPRLEVRDFLDNHDIVTEAWSPLGRGADGVLNAPA-------VLDAAKKHGITPAAAVL 223
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
+ + G++ IPKS + + N++ L+ E++ +
Sbjct: 224 AWELNQGIVTIPKSANPEHQRTNLEAIGVELSAQEMKAI 262
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 154 bits (374), Expect = 3e-36
Identities = 94/283 (33%), Positives = 158/283 (55%), Gaps = 19/283 (6%)
Query: 32 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKK 91
+G E+P G+G + + DE +VE A+ GYRHIDTAA Y E +VG I++
Sbjct: 25 SGVEMPMIGLGVF------QTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRA 78
Query: 92 IAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASI 151
G+ R+++F+ TK+W +++ + L A KS L +D +DL L+H P+ ++
Sbjct: 79 ---GIA-RDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQPLP----SAF 130
Query: 152 SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPA 211
+T + ++A+ +L G ++IGVSNF + L RL +E + P+V Q+E++ QQ A
Sbjct: 131 DRT--LGAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRA 188
Query: 212 LLDYCKAQGIVVVAYTPFGNL-FNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVE 270
L GI+ A++P G + F R +D L+ IAQ++ K+ Q++LR+ ++
Sbjct: 189 LQRLHAEHGILTQAWSPIGGITFYR--GGEKSTLEDPVLLEIAQQHGKSAAQVMLRWHLQ 246
Query: 271 LGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRT 313
G IPKS R+ EN ++DF L+ ++I + + D G R+
Sbjct: 247 EGRSVIPKSTKPARIAENFDVFDFELSGEQIAAIDALDTGVRS 289
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 154 bits (374), Expect = 3e-36
Identities = 105/321 (32%), Positives = 166/321 (51%), Gaps = 48/321 (14%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAI-DAGYRHIDTAAIYSTEDQVGRA 87
+L +G +IP G+GTW G + +V AI + GYRHIDTA Y + +VG+
Sbjct: 17 RLLSGHKIPAVGLGTWRS-------GSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQG 69
Query: 88 IKKKIAEGVVKREDLFVTT---------KLWN------------------TNHKKEAVLP 120
IK+ + G+ +R DLFVT+ K+ N T E V P
Sbjct: 70 IKRAMHAGL-ERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRP 128
Query: 121 ALRKSLKNLDLDYVDLYLIHWPIALHDNAS-------ISQTDYVETWQAMTDVLNQGLTK 173
AL+ +LK L L+Y+DLYLIHWPI L + AS + D W+ M ++ L +
Sbjct: 129 ALQNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVWREMENLSKDSLVR 188
Query: 174 SIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLF 233
+IGV NF + +L +L + P+V Q+E++ + +L++CK I V AY+P G+
Sbjct: 189 NIGVCNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYSPLGS-- 246
Query: 234 NRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYD 293
DQ + IA+K KT QI++++ ++ G IPKSL+ +R++ENI+++D
Sbjct: 247 ---QEGGRDLIHDQTVDRIAKKLNKTPGQILVKWGLQRGTSVIPKSLNPERIKENIKVFD 303
Query: 294 FSLTPDEIQLLKSFDNGYRTL 314
+ + + Q L S + R +
Sbjct: 304 WVIPEQDFQALNSITDQKRVI 324
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 154 bits (374), Expect = 3e-36
Identities = 95/280 (33%), Positives = 152/280 (54%), Gaps = 31/280 (11%)
Query: 33 GKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKI 92
G+++ G+GTW S E E +S+ +A+D G IDTA +Y TED VG AIK
Sbjct: 13 GRKVSVIGVGTW----SLEGSRSENVRSIRYALDHGVNFIDTAEMYGTEDIVGEAIKG-- 66
Query: 93 AEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASIS 152
+REDLF+ TK+W T+ VL + +SLK L DYVDLY +HWP N S+S
Sbjct: 67 ----YRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP-----NPSVS 117
Query: 153 QTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVL-QVEINL---NLQ 208
ET AM ++++G + IG+SNF++++++ S V Q+E N+ ++
Sbjct: 118 ---IKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAMSALAKYRIVSNQLEYNVATREIE 174
Query: 209 QPALLDYCKAQGIVVVAYTPF--GNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLR 266
+ D+C+ G+ ++AY+P G +F + + L I +KY K Q+ L
Sbjct: 175 DEGIYDFCRKNGMAIIAYSPLSHGKIFGNEMIL-------ETLTDIGKKYGKRPAQVALN 227
Query: 267 YLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
+++ G PIPK+ + ENI+ DF+L+ ++++ L S
Sbjct: 228 WIIRKGAFPIPKASKPIHMAENIESTDFTLSDEDMKTLDS 267
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 153 bits (370), Expect = 8e-36
Identities = 95/292 (32%), Positives = 157/292 (53%), Gaps = 19/292 (6%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
+ P ++L +G ++P G+GT+ + +LK +SV A+ AGYR DTAA+Y E
Sbjct: 2 IVPSVRLMSGTQMPLLGLGTYKLQDHEQLK-----QSVSCALQAGYRAFDTAAVYGNEAH 56
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP- 142
+G+ +K+ + + + RED+F+ +KL ++H A LR SL+ LD +Y+DLYLIHWP
Sbjct: 57 LGQVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPG 115
Query: 143 IALHDNASISQTDY-VETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQV 201
+ D ++Y ++W + + G K+IGVSN+ + + L + V P+VLQ+
Sbjct: 116 MEGLDPEDSRHSEYRAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAVLQI 175
Query: 202 EINLNLQQPALLDYCKAQGIVVVAYTPFG-NLFNRQPSAPAPRADDQRLVAIAQKYKKTV 260
E L Q L D C GI AY+ G R+P ++ I + +T
Sbjct: 176 ECQPKLIQRELRDLCMETGIHFQAYSSLGKGALLREP----------EVMDIVRHCGRTP 225
Query: 261 PQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
Q++LR+ ++ G+ +P+S RV EN Q++DF L +++ L + G R
Sbjct: 226 AQVLLRWALQQGISVLPRSSQPSRVLENAQVFDFKLNETDMKRLDDLNCGTR 277
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 153 bits (370), Expect = 8e-36
Identities = 96/279 (34%), Positives = 145/279 (51%), Gaps = 25/279 (8%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P + L++G IP G GT+ L G++ +++ AID GYR IDTA Y E VG
Sbjct: 6 PNVTLHDGLTIPKVGFGTY------RLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVG 59
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
A+++ RE L +T+KL H + + +++SL +LDY DLYLIHWP +
Sbjct: 60 EAVRRSSTP----REQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPNPI 115
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
D YVE WQA+ + +G +SIGV NF + LERLK E G P++ Q+E++
Sbjct: 116 QDI-------YVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQIELHP 168
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
Q + + I +++P + D L +A + +TV QI+L
Sbjct: 169 FFNQEDQRKWHQEHQIATESWSPLARTND--------VLDHPVLQKLASNHNRTVSQIIL 220
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
R+ +L I IPKS R ENI I+DF L+ +E+ ++
Sbjct: 221 RWHYQLDAIAIPKSATPSRQLENISIFDFELSDEEMSII 259
>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
YvgN - Bacillus sp. NRRL B-14911
Length = 268
Score = 153 bits (370), Expect = 8e-36
Identities = 102/285 (35%), Positives = 148/285 (51%), Gaps = 27/285 (9%)
Query: 28 LKLNNGKEIPGFGIGT-WLGTNSNELKGDEVQKSVEWA--IDAGYRHIDTAAIYSTEDQV 84
+ LNNG E+P G GT G +N+ GD + E A I+ GYR ID A +Y E+ V
Sbjct: 4 ITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPELASAIELGYRSIDAAIMYRNEELV 63
Query: 85 GRAIKKKIAEGVVKREDLFVTTKLWNTNH---KKEAVLPALRKSLKNLDLDYVDLYLIHW 141
G + AE V RE+ F+TTK+ + KEA A+ SLKN DY+DL LIH+
Sbjct: 64 GSVL----AESKVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLIHF 119
Query: 142 PIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQV 201
PI D + T W+ + G K+IGVSNF L+ LK V P+V Q+
Sbjct: 120 PI--EDKVQLKNT-----WEVFEEYYEAGKLKAIGVSNFEENHLDELKEFAKVKPAVNQI 172
Query: 202 EINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVP 261
+INL LL K + I VA+ P A + L I + Y K+
Sbjct: 173 QINLKEPNKNLLAVLKDEEITPVAWGPM----------KAEAHQKEALDEIGKIYHKSGA 222
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
QI+L+Y ++ GVI IPKS +++ N++++DF LT ++I+ +++
Sbjct: 223 QILLKYQIQRGVIVIPKSHNRENQASNLELFDFELTAEDIEKIEN 267
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 152 bits (369), Expect = 1e-35
Identities = 95/315 (30%), Positives = 160/315 (50%), Gaps = 22/315 (6%)
Query: 17 HLSPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAA 76
H L P +L G +P GIGT+ S+ EV +V A+ AGYR +D AA
Sbjct: 5 HAPVDPALVPRRELRGGATVPAIGIGTF---GSDRYSPAEVAAAVAGAVAAGYRLVDCAA 61
Query: 77 IYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDL 136
+Y E QVG A+ +A GV R++LFV +K+WN H + ++ +SL++L LD++D
Sbjct: 62 VYGNEAQVGEALAGAVAGGV-DRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDA 120
Query: 137 YLIHWPIALHDNASISQTD-------------YVETWQAMTDVLNQGLTKSIGVSNFNIQ 183
+HWP H + ++ TD Y+ W A+ +++ GL + +G SN +
Sbjct: 121 VFVHWPFPNH-HPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVA 179
Query: 184 QLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN-RQPSAPAP 242
+L+ L + + P++ ++E++ QQP L +C GI V Y+P G+ + P
Sbjct: 180 KLDLLLRDARIPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSPLGSPSRPERDRTPGD 239
Query: 243 RAD--DQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQ-IYDFSLTPD 299
D D +V IA+++ + L++ V G +PIP S+ + N++ + + LT
Sbjct: 240 VVDTEDPVVVRIAREHGVHPALVCLKWAVARGQVPIPFSVKPAQYTANLRAVVEDPLTAQ 299
Query: 300 EIQLLKSFDNGYRTL 314
E+ L + D G R +
Sbjct: 300 EVADLAAADRGERLI 314
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 152 bits (368), Expect = 1e-35
Identities = 92/252 (36%), Positives = 146/252 (57%), Gaps = 20/252 (7%)
Query: 26 PVLKLNNGKEIPGFGIGTW---LGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTED 82
P L++GK +P G+GT LG D V + AI+AGYRH DTAA+Y TE
Sbjct: 2 PEAALSSGKPMPRVGMGTASFPLGATDPSTVKDVVLR----AIEAGYRHFDTAAVYQTEA 57
Query: 83 QVGRAIKKKIAEGVV-KREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHW 141
+G A+ + + G+V R++L++T+KLW + VLP+LR++L+ + ++Y+DLYLIH+
Sbjct: 58 ILGDAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHF 117
Query: 142 PIALH-----DNASISQTDYVE-----TWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSE 191
P+++ ++ + S+ D V W+ M + GLTK+IGVSNF+ ++LE L S
Sbjct: 118 PVSMRLAEDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSF 177
Query: 192 GGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVA 251
++P+ QVE++ +Q L ++CK +GI + AY+P G P + D L
Sbjct: 178 ATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSPLGG--KGTPWSNNAVMDCPLLKQ 235
Query: 252 IAQKYKKTVPQI 263
IA + KT+ QI
Sbjct: 236 IAMERGKTIAQI 247
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 151 bits (367), Expect = 2e-35
Identities = 100/284 (35%), Positives = 160/284 (56%), Gaps = 31/284 (10%)
Query: 33 GKEIPGFGIGTW-LG--TNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYS---TEDQVGR 86
G+EIP G+GTW +G + + +E+ + ++ AI GY HIDTA Y TE+ +G+
Sbjct: 10 GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELIGK 69
Query: 87 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH 146
AIK +REDLF+ +K+W T+ +++ +L +L +LK LD DYVDLYLIHWP
Sbjct: 70 AIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP---- 119
Query: 147 DNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 206
N I ET AM + + QGL + IGVSNF+ + LE S+ QV+ N+
Sbjct: 120 -NPEI---PLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVKYNIE 175
Query: 207 LQQP---ALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+ P LL++C+ G+ +VAY+P + + + L IA+ + T+ QI
Sbjct: 176 DRDPERDGLLEFCQKNGVTLVAYSPLRRTLLSEKT-------KRTLEEIAKNHGATIYQI 228
Query: 264 VLRYLV-ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
+L +L+ + V+ IPK+ + + EN++ + L+ +E++LL S
Sbjct: 229 MLAWLLAKPNVVAIPKAGRVEHLRENLKATEIKLSEEEMKLLDS 272
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 151 bits (367), Expect = 2e-35
Identities = 100/280 (35%), Positives = 146/280 (52%), Gaps = 24/280 (8%)
Query: 45 LGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFV 104
LGT + LK + +V A++ G RHIDTA IY E VG AI G+ RE+LF+
Sbjct: 20 LGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAIN---TSGI-PREELFI 75
Query: 105 TTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTDYVETWQAMT 164
TTK+W N KE ++ SL L Y+DL LIHWP+ ++ S +Y+ +A
Sbjct: 76 TTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPL---NSDEPSMVEYLSELKA-- 130
Query: 165 DVLNQGLTKSIGVSNFNIQQLER---LKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGI 221
VL++GLT+ IGVSNF QL + + EG + + QVE++ L + D+C+ +
Sbjct: 131 -VLDKGLTRRIGVSNFTNAQLAQAIAILGEGVIYTN--QVEVHPYLINRKVTDFCRQHNV 187
Query: 222 VVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLH 281
+V Y PF A D+ +V +A ++ T QIVL +L +LG IP S
Sbjct: 188 LVTGYMPF---------AYGAVLQDETIVNLASVHQATPAQIVLAWLRQLGFATIPSSTK 238
Query: 282 KDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLFWAH 321
+D V N+ +LTP EI+ + D +R +P F H
Sbjct: 239 RDNVRSNLAAASINLTPAEIEQINQLDRNHRVANPDFAPH 278
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 151 bits (366), Expect = 2e-35
Identities = 98/276 (35%), Positives = 148/276 (53%), Gaps = 26/276 (9%)
Query: 35 EIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAE 94
+IP G+GTW L G + ++V I+AGYR IDTA IY ED VG A+ AE
Sbjct: 3 DIPPLGLGTW------PLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVAL----AE 52
Query: 95 GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQT 154
V RE+LFVTTKL ++H + A+ +SLKNL LD +DL+LIHWP+ H+
Sbjct: 53 CGVPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPLPRHNR------ 106
Query: 155 DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLD 214
YV ++AM + GL + +GVSNF L R+ +E G +P+V Q++++ +L + +
Sbjct: 107 -YVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSLARLPVRR 165
Query: 215 YCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVI 274
G+ +++P G R +P D IA++ +T Q+VL + GV+
Sbjct: 166 ADDELGVSTQSWSPLG----RGEVLGSPVVTD-----IARRLDRTPAQVVLAWHFAQGVV 216
Query: 275 PIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
P+ +S + R EN+ D LT ++ L D G
Sbjct: 217 PVARSANPARQAENLAALDVRLTAADVDALNRLDRG 252
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 151 bits (365), Expect = 3e-35
Identities = 96/279 (34%), Positives = 154/279 (55%), Gaps = 28/279 (10%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LN+G IP FG+G + +G+ + +V+ A+ GYRHIDTA Y E VGRAI
Sbjct: 7 LNDGNIIPQFGLGVY-----QIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIH 61
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
+ G+ E +++T+KLW +++ + A+ + L+ L+L +DL L+H +
Sbjct: 62 ---SSGIPISE-IWITSKLWPSDYDDAS--QAIERMLELLNLKQIDLLLLHQQVG----- 110
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
+Y + W A+ + + G KSIG+SNF+ ++L L + + PS LQVE + QQ
Sbjct: 111 -----NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVETHPYHQQ 165
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
L ++ K G + ++ P G+ R D+ RL IAQKY KTV QI+LR+ +
Sbjct: 166 KELQEFLKPYGTKIESWYPLGHGDQRL-------LDESRLKKIAQKYNKTVAQIILRWHI 218
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
+ G+I P+S + + ENI I+DF L+ EI+ ++ D
Sbjct: 219 QEGIIVFPRSTRVEHLAENINIFDFELSCTEIKEIRKLD 257
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 151 bits (365), Expect = 3e-35
Identities = 106/308 (34%), Positives = 163/308 (52%), Gaps = 31/308 (10%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LN G +IP G+GT+ +S E ++V + G R IDTA +Y E QVGR IK
Sbjct: 40 LNTGAKIPALGVGTFQDPDSQE-------ETVCQVLQRGMRLIDTARVYGVEQQVGRGIK 92
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH--- 146
K V RE++F+ TKLW + + V A+ SL++L YVDL L+H+P
Sbjct: 93 KS----GVPREEIFLGTKLWCNDFHPDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGE 148
Query: 147 -------DNASI-SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
+ I +T +V+TW+A+ V+ G ++IGVSNF+ ++E L E P+V
Sbjct: 149 DRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAV 208
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNL--FNRQPS-----APAPRADDQRLV- 250
Q+E++ LQQ ++ + +GI VV ++P GN+ F RQ A R DQ ++
Sbjct: 209 HQMEVHPYLQQKGFNEWLREKGIHVVQFSPLGNMNDFYRQAGWSKEIAHMMRVIDQPILK 268
Query: 251 AIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
I QKY K+ Q+VL + + G IPK++ ++EEN+ DF L +++ + + D
Sbjct: 269 EIGQKYGKSPVQVVLAWGINSGRSVIPKTVIDWQIEENLAA-DFELDAEDMARIATLDAK 327
Query: 311 YRTLSPLF 318
R P F
Sbjct: 328 ARFNDPSF 335
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 151 bits (365), Expect = 3e-35
Identities = 90/281 (32%), Positives = 160/281 (56%), Gaps = 27/281 (9%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KL+NG +IP +GT+ ++ + + V + GYRH DTA +Y E +VG I
Sbjct: 7 KLSNGFKIPSIALGTY------DIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGI 60
Query: 89 KKKIAE--GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLD-LDYVDLYLIHWPIAL 145
K + E G KRE++F TTKLWN+ + + A+R+ L + L Y+DL LIH P+
Sbjct: 61 IKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL-- 118
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKS--EGGVTPSVLQVEI 203
+ + + +ETW+AM + +++GL KSIGVSN+ + ++ L + E P V Q+EI
Sbjct: 119 -EGSKLR----LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEI 173
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+ + + L DYCK++G+VV A+ P + + + + L+ + ++ + Q+
Sbjct: 174 SPWIMRQELADYCKSKGLVVEAFAPLCHGY---------KMTNPDLLKVCKEVDRNPGQV 224
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
++R+ ++ G +P+PK+ R+E N+ Y+F L+ ++++ L
Sbjct: 225 LIRWSLQHGYLPLPKTKTVKRLEGNLAAYNFELSDEQMKFL 265
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 149 bits (362), Expect = 7e-35
Identities = 96/281 (34%), Positives = 147/281 (52%), Gaps = 26/281 (9%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
IP G GTW DE + V WA++AG RHIDTA Y E V R IK +
Sbjct: 10 IPQMGYGTW------NRSADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIK----DA 59
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTD 155
V R ++F+TTK+ N+ AV+P++R+SL+ L +D VDL L+HWP + H+ ++ D
Sbjct: 60 GVARNEIFITTKVKPDNYGPGAVMPSVRESLEKLRVDQVDLLLLHWP-SPHNKYPLA--D 116
Query: 156 YVETWQAMTDVLNQGLTKSIGVSNFNIQQL-ERLKSEGGVTPSVLQVEINLNLQQPALLD 214
Y+ + +V + GL + IGVSNF + E ++ T + QVE ++ +Q ++D
Sbjct: 117 YLGQF---AEVFDSGLARQIGVSNFTKAMIDESIRLLDSRTITTNQVECHVYMQNRPIID 173
Query: 215 YCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVI 274
YC+ GI V AY+P A D L I + T QI L +L+ G +
Sbjct: 174 YCQNLGIAVTAYSPL---------ARGAVVGDPVLEEIGKARGATSDQIALAFLIAKGHV 224
Query: 275 PIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLS 315
IP S + R+ +N + +LTP EI+ ++ + G R ++
Sbjct: 225 VIPSSSKRGRIMQNFEARKITLTPAEIKRIEGLEKGMRLVN 265
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 149 bits (361), Expect = 1e-34
Identities = 101/291 (34%), Positives = 154/291 (52%), Gaps = 28/291 (9%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
+L++G +IP G+G + ++ VQ V A++ GYR D+A Y ED V R I
Sbjct: 14 RLSDGTQIPSVGLGVY------QVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGVARGI 67
Query: 89 KK--KIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLD-LDYVDLYLIHWPIAL 145
K A G +RED++ TTK+ NH EA +L KSL L Y+DL L+H P++
Sbjct: 68 AAWLKHAPGR-RREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAPMS- 125
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGG--VTPSVLQVEI 203
+T + TWQA+ + + +G +SIGVSN+ Q L L G + P V QVEI
Sbjct: 126 ------DRTRRLGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVEI 179
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
N L + L+ YC+ I V A++P R DD L +A +Y K V QI
Sbjct: 180 NPWLCRQELVQYCRENNIAVQAFSPLMR---------GKRLDDPILQKVAHQYDKGVAQI 230
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTL 314
++R+ +++G I +PK+ K+R+ N I+DF L+ + + L D+ + T+
Sbjct: 231 LVRWSIQMGFIVLPKAAKKERLAPNFDIWDFELSAETMSELTHSDDYFVTV 281
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 149 bits (361), Expect = 1e-34
Identities = 99/294 (33%), Positives = 151/294 (51%), Gaps = 21/294 (7%)
Query: 24 LAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
+ P L+N E+P G+GT T+S D V S++ GYR IDTA Y E Q
Sbjct: 1 MIPTTVLSNNVEMPLIGLGT---THSGGYYHDAVLHSIK---KCGYRLIDTAKRYGVEKQ 54
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
+G A+K V RE++F++TKLW + E V A + S + L DY+D+Y+IH P
Sbjct: 55 LGIAVKNCS----VPREEMFLSTKLWPVDCGDE-VYNAFQTSCEKLQTDYLDMYMIHMP- 108
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
L D + +TW+ M + +SIGVSN++I+ L+ L + P QVE+
Sbjct: 109 QLPDWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHANQVEL 168
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
+ Q L +YC GI+ + Y P A +D+ L IA KY+K+ QI
Sbjct: 169 HPWFHQADLKNYCDELGILTMGYCPL---------AKGKYLEDETLCKIASKYQKSPAQI 219
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPL 317
LR+ ++ V +PKS R++EN ++DF L+ +++ L SF + R + L
Sbjct: 220 CLRWSIQQNVPTVPKSTDCRRLKENTNVFDFELSAEDMNTLNSFSSQNRKIVDL 273
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 149 bits (360), Expect = 1e-34
Identities = 89/282 (31%), Positives = 166/282 (58%), Gaps = 18/282 (6%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDE-VQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
L++G ++P G GT+ +++G E V + V+ +++ G+R IDTA Y E+ +G A+
Sbjct: 10 LSSGYDMPLIGFGTY------KIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYAL 63
Query: 89 KKKIAEGVVKREDLFVTTKL-WNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA--L 145
K + + ++R D+F+TTKL + N + + ++KSLK + Y+DLYLIHWP A +
Sbjct: 64 KNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATRI 123
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL-ERLKSEGGVTPSVLQVEIN 204
+ ++ + + +TW + D+ QG +SIGVSNF I+ L E L++ + P+V QVE++
Sbjct: 124 PETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVELH 183
Query: 205 LNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIV 264
+ +Q L+ YC +GI + AY+ G S + ++ IA + + +++
Sbjct: 184 PHYRQEELIKYCNEKGIHIQAYSSLGT------SGNINLLRNPIVLKIASQLNVSSARLL 237
Query: 265 LRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
L + ++ G+ IPK+++K+ +++NIQ+ DF + + + +L S
Sbjct: 238 LNWALQQGIGVIPKAVNKEHIKDNIQL-DFLIDEESMNILFS 278
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 149 bits (360), Expect = 1e-34
Identities = 92/275 (33%), Positives = 149/275 (54%), Gaps = 29/275 (10%)
Query: 51 ELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWN 110
+L+G + +V AI+ G+RH DTA Y E ++G A++ +I G + RE++F+TTKLWN
Sbjct: 40 KLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWN 99
Query: 111 TNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH------------DNASISQTDYVE 158
T+H V K L+ L Y+DLYL+H+P+ D + DY++
Sbjct: 100 THHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLD 159
Query: 159 TWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKA 218
TW+AM +++ G+ +SIG+SNFN++Q++R+ P V QVEI Q L+DYC+
Sbjct: 160 TWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRY 219
Query: 219 QG----IVVVAYT-------PFGNLFNRQPS--APAPRADDQRLVAIAQKYKKTVP---Q 262
G + +++ P LF R + + A +LVAI ++
Sbjct: 220 NGNYCDSLFTSWSTKQKKSLPSVFLFGRCETDWLRSTSALQVKLVAIFGSIFISIRLNLN 279
Query: 263 IVLRYL-VELGVIPIPKSLHKDRVEENIQIYDFSL 296
I +R L ++ GV+PIPK+ + ++EN+ I+DF L
Sbjct: 280 INIRILEIDYGVVPIPKAANPIHIKENLNIFDFKL 314
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 149 bits (360), Expect = 1e-34
Identities = 103/308 (33%), Positives = 160/308 (51%), Gaps = 20/308 (6%)
Query: 26 PVLKLNNGKEIP--GFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
P +KL+NG EIP GFG GT E + E+ +V AI+AG+ HIDTA Y TE Q
Sbjct: 4 PKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEKQ 63
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
+G AIK E V R+D+F+T+K + + ++ LK L DY DL+LIH P
Sbjct: 64 IGEAIK----ESGVPRKDIFLTSKTL-FGLLADDPIESISNQLKTLQTDYFDLFLIHVP- 117
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
N I+ D + W + + +GL K+IGVSN + +LE + + P V Q+E
Sbjct: 118 ---PNDDINY-DLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHVNQIEF 173
Query: 204 NLNLQQ--PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVP 261
+ LQ+ P ++D+CK IVV Y+P L + + P D + +A+ + +
Sbjct: 174 HPLLQEPTPGIVDFCKQHDIVVEGYSP---LASNELEGEKPL--DAVVANVAKNHNVSPG 228
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEI-QLLKSFDNGYRTLSPLFWA 320
++LR+ + G++PI S + R +E + I+DF L+ E+ ++ K R +
Sbjct: 229 SVLLRWATQKGIVPITTSANAGRQKEALAIFDFKLSDGEVEEISKVGAESPRYQRLPIPS 288
Query: 321 HSPYFPFE 328
H Y+P E
Sbjct: 289 HKHYYPAE 296
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 147 bits (357), Expect = 3e-34
Identities = 103/295 (34%), Positives = 155/295 (52%), Gaps = 35/295 (11%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P LN G ++P G+G W G + +E+ ++ AI GYRH+DTA Y E +VG
Sbjct: 6 PSFTLNTGAKLPSVGMGCWQG-QPGPGRDNELVDALVRAIKVGYRHLDTATGYRNEAEVG 64
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP--- 142
+A+++ GV R ++FVTTKL V+ L SL L +DY+DL+L+HWP
Sbjct: 65 QAVRQS---GVA-RSEIFVTTKLRPGG--VHDVVQELENSLNELGIDYIDLWLLHWPQGF 118
Query: 143 ------------IALHDNASISQTDYVETWQAMTDVL---NQGLTKSIGVSNFNIQQLER 187
L + T + ETW M DV ++G K+IGVSNF+I+ LE
Sbjct: 119 TKDDGGFGTGESFGLEHQKHLGPT-FNETWAKMEDVFLNSHKGKVKAIGVSNFSIKNLEI 177
Query: 188 LKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQ 247
L VTP+V Q+E + L + L+ YCK + I V AY+P G +N A +D+
Sbjct: 178 LAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSPLGQ-YN------ASIHEDK 230
Query: 248 RLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQ 302
L IA+K+ T + L + V+ G PKS ++ R+++NI + LT +E++
Sbjct: 231 DLNEIAKKHDVTAATVALSWAVQRGTSVAPKSTNEKRMKQNITL--IKLTDEEMK 283
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 147 bits (356), Expect = 4e-34
Identities = 94/283 (33%), Positives = 141/283 (49%), Gaps = 15/283 (5%)
Query: 30 LNNGKEIPGF---GIGT-WLGTNSNELK-GDEVQKSVEWAIDA-GYRHIDTAAIYSTEDQ 83
LNNG +IP G GT W +E DE+ + +++A+ G HID A Y T +
Sbjct: 10 LNNGNQIPSISIIGTGTRWFKRPGSEHTFSDELVEQIKYALSLPGIIHIDAAECYGTYPE 69
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
+ +A+K E R ++F+T K + L LK L LDYVDLYLIH P
Sbjct: 70 LAKALK----ESSKPRSEIFITDKYSTQTKFTNDPIEGLNTGLKTLGLDYVDLYLIHSPF 125
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
D + W+ M + +G KSIGVSNF+++ +E + G+ P V Q+E
Sbjct: 126 --FDPEFKGSLTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGIKPQVNQIEF 183
Query: 204 N--LNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVP 261
N L Q P +++YC+ I + AY+P G L ++P + +A KY KT
Sbjct: 184 NAFLQNQTPGIVNYCQKNNIQLEAYSPLGPL-QKRPENSNELPFYNYIDELASKYGKTDS 242
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
QI+L ++ G++PI S R+ + I+ F+LT DE+ L
Sbjct: 243 QILLNWVYNRGILPITTSSKTQRIIDAQNIFSFNLTKDEVDTL 285
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 147 bits (355), Expect = 5e-34
Identities = 92/279 (32%), Positives = 144/279 (51%), Gaps = 29/279 (10%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
LN+G +P G G + +L + + V D GYR +DTAA Y E+ VG ++
Sbjct: 9 LNDGHSMPAIGQGVY------QLNPAQAESMVALGYDLGYRAVDTAAWYENEEGVGEGLR 62
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
+ A F+TTKL + + AL KS++NL + ++LYLIHWP
Sbjct: 63 SRHARS-------FITTKLMPQDMGRVNCFVALDKSIRNLGVTSLNLYLIHWP------- 108
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
+ Y ETWQ + + G SIGVSNF I L+ + ++ GV P+V Q+E++ QQ
Sbjct: 109 GQDRKRYEETWQTLIQIRAIGKASSIGVSNFTIDHLDHIIADSGVVPAVNQIELHPYFQQ 168
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
L Y +GIV +++P G +D + IA K+ KT Q+VL + +
Sbjct: 169 KELRAYHAERGIVTTSWSPLGR---------GAALNDPVIREIALKHGKTPAQVVLNWHL 219
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
LG+ IPK+ K R++EN++ F+L +++Q ++S D
Sbjct: 220 SLGLTVIPKASSKARLQENLEADSFALDEEDMQRIESLD 258
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 146 bits (354), Expect = 7e-34
Identities = 83/201 (41%), Positives = 117/201 (58%), Gaps = 8/201 (3%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KLNNG+ +P G+GT+L NS E E+ + A+DAGYRHIDTA Y E +G ++
Sbjct: 9 KLNNGQIMPLVGLGTYL-LNSKE----EMTNLLRTALDAGYRHIDTAVNYQNEAMIGESL 63
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA-LHD 147
K EG R+DLF+ +K++ +K +L +++KSLK L LDYVDLY +H+P+ L +
Sbjct: 64 KTIFKEGKYSRKDLFIVSKVFP--NKGINMLESVKKSLKELQLDYVDLYYLHFPLGFLSE 121
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
W + + GL KSIGVSNFN+ L L S V P QVE+++ +
Sbjct: 122 KEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVSVFI 181
Query: 208 QQPALLDYCKAQGIVVVAYTP 228
QQ L+ +C+ GI V AY P
Sbjct: 182 QQKNLIKFCQRFGIHVTAYAP 202
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 146 bits (354), Expect = 7e-34
Identities = 102/277 (36%), Positives = 152/277 (54%), Gaps = 32/277 (11%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
KLN+G IP G+GT ++ N V++ V AI GYRHIDTA IY +E VG+ I
Sbjct: 8 KLNDGHSIPALGLGT--ASDGN------VEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGI 59
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL--- 145
K+ I E +VKRE+LFVTTK+W T + + V +L SLK+L LDYVDL L+HWP++L
Sbjct: 60 KRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPVSLLAD 117
Query: 146 ----------HDNASI----SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSE 191
+ + S+ S D++ T++ + + G TKSIGVSN + L+RL +
Sbjct: 118 SDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQ 177
Query: 192 GGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVA 251
P+V Q EI+ L Q +++ + GI+V A++P G+ P A V
Sbjct: 178 VKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSPLGSSTGALKLHENPIA-----VE 232
Query: 252 IAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEEN 288
IAQK+ + +++ + V +PK+ +RV N
Sbjct: 233 IAQKHNTSTGSVLINWHVSQKRAVLPKTRSIERVVAN 269
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 145 bits (351), Expect = 2e-33
Identities = 96/282 (34%), Positives = 146/282 (51%), Gaps = 26/282 (9%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
+P FG+GT+ LK V SV A+ GYR IDTA IY E QVG+AI A+
Sbjct: 3 VPAFGLGTF------RLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAI----ADA 52
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTD 155
V R+ LFVTTK+W ++ + P+L++SL+ L DYVDL LIHWP + +
Sbjct: 53 GVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP---SPKDQVPMRE 109
Query: 156 YVETWQAMTDVLNQGLTKSIGVSNFNIQ-QLERLKSEGGVTPSVLQVEINLNLQQPALLD 214
Y+E A+ D QGLT++IGVSNF I + ++ G + Q+E++ LQ L+
Sbjct: 110 YLE---ALADAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVHPYLQNRTLIA 166
Query: 215 YCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVI 274
+ + QGI V +Y A D + AIA+++ T Q+ L + ++ G
Sbjct: 167 FLREQGIHVTSYMTL---------AVGEVLKDPVIQAIARRHDATPAQVTLAWALQQGYS 217
Query: 275 PIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSP 316
IP S + +E N++ L+ ++ + + D G R +P
Sbjct: 218 VIPSSTKRANLESNLKAQSLHLSEQDMAEIAALDRGERLANP 259
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 144 bits (349), Expect = 3e-33
Identities = 92/271 (33%), Positives = 144/271 (53%), Gaps = 18/271 (6%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
+P +G+GT L + SV+ A+ AG+ HID A +Y E++VG A+K E
Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALK----EA 67
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTD 155
V R LF+T+K+ H + + AL +SL+ L DY+DLYL+H PI ++ +
Sbjct: 68 NVPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEK----KIP 120
Query: 156 YVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPA--LL 213
E W+AM L GL S+GVSNF I LE L +TP V Q+E + + + A L+
Sbjct: 121 ISEGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAKPLV 180
Query: 214 DYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGV 273
++C+++GI+V Y P L A P A+ + ++ KY + QI+L++ GV
Sbjct: 181 EFCQSKGIIVEGYGPLSPLVR---DAQGPVAEFTK--SLESKYHVSDTQILLKWAYSKGV 235
Query: 274 IPIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
IPI + +R++E + F+L +I L
Sbjct: 236 IPITTTSKIERMKECLNFDSFTLDKADIDEL 266
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 144 bits (348), Expect = 4e-33
Identities = 94/283 (33%), Positives = 147/283 (51%), Gaps = 27/283 (9%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIK 89
L + IP G+G + T + G +VE AI+ GYR DTAA+Y+ E VG+AI
Sbjct: 11 LPGNETIPYIGLGVFQVTEQEFIAG-----AVEKAIEVGYRLFDTAAVYNNEAIVGQAI- 64
Query: 90 KKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNA 149
+ V RE+LF+++K+WN + + L A ++L+NL LDY+DLYLIHWP+A
Sbjct: 65 ---LDSAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVA----- 116
Query: 150 SISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQ 209
Y ++W+AM + ++ L KSIGV+NF L L P + QVE + L Q
Sbjct: 117 ----GKYRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVETHPLLPQ 172
Query: 210 PALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV 269
L Y Q I A++P A + + IA+K++ +V Q++L++ +
Sbjct: 173 NDLRKYLAEQNIAHAAWSPL---------AKGILMQNPVITEIAKKHQASVDQVILQWHL 223
Query: 270 ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
I PKS+ R+EEN ++ F L +++ + + G R
Sbjct: 224 NRNTIIFPKSITSSRIEENSRLSYFQLDASDMEKIDRLETGKR 266
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 144 bits (348), Expect = 4e-33
Identities = 92/274 (33%), Positives = 141/274 (51%), Gaps = 20/274 (7%)
Query: 46 GTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVT 105
G + LKGD+ + +VE A+D GYRHIDTA Y E +VG AI + + R +LFVT
Sbjct: 15 GFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAI----SASKISRGELFVT 70
Query: 106 TKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTDYVETWQAMTD 165
TK+W N + + +++ SL L+ DYVDL L+HWP DN +S +Y++ +A +
Sbjct: 71 TKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWPSP--DN-KVSMAEYLKELKACKE 127
Query: 166 VLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVL-QVEINLNLQQPALLDYCKAQGIVVV 224
+GLT+ IGVSNF QL+ S G + Q+E++ N Q L+ YC+ I V
Sbjct: 128 ---RGLTRHIGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVT 184
Query: 225 AYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDR 284
AY P G ++ L IA + T + L +L ++ IP S + +
Sbjct: 185 AYMPLG---------VGKVMENDILNDIASAHDTTPSAVALAWLSHKKIVAIPSSTNVNH 235
Query: 285 VEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLF 318
+ +N+ LT +EI+ + + R + P F
Sbjct: 236 MRDNLTAKQMMLTAEEIEKIDGIEPQERIVDPDF 269
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 143 bits (346), Expect = 6e-33
Identities = 97/282 (34%), Positives = 145/282 (51%), Gaps = 32/282 (11%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
+P G+GTW T+ E ++V A D GYR +DT+ Y T+ +G AI+ A G
Sbjct: 1 MPILGLGTWQLTH-------ETARTVRAAFDLGYRMVDTSGDYGTQSAIGEAIR---ASG 50
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTD 155
+ R+D+++ TK+ T E A + +L+ L LDY DL LIH P H
Sbjct: 51 L-DRDDIYLVTKVEET----EDAYNATQANLRELGLDYADLILIHRP-PRHGAGE----- 99
Query: 156 YVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDY 215
E W+A+ GLT+ IGVSN++I+ +E L G P V QVE + L Y
Sbjct: 100 --ELWRALIRAREDGLTRDIGVSNYSIELIEELVDATGEIPVVNQVEWSPFGHDLELKHY 157
Query: 216 CKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIP 275
GIV+ AY+P A R DD L A+KY KT Q+++R+ +E G +P
Sbjct: 158 ADFNGIVIQAYSPLTR---------ATRLDDAALCETAEKYGKTPAQVLIRWNLERGTVP 208
Query: 276 IPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPL 317
IPK+ ++ENI ++DF+L +++ L S + + +L L
Sbjct: 209 IPKANLHSHMKENISVFDFTLEKSDLESLDSLNEHFSSLGRL 250
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 142 bits (344), Expect = 1e-32
Identities = 102/276 (36%), Positives = 149/276 (53%), Gaps = 37/276 (13%)
Query: 37 PGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGV 96
P G+GT+ G N +G V+++V A+ GYRHIDTA Y E +VG AIK E
Sbjct: 47 PAVGLGTFQGDAGN--RG--VKEAVLQALRCGYRHIDTATAYGNEIEVGEAIK----ESR 98
Query: 97 VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDY---VDLYLIHWPIALH------D 147
+ RE++ VTTKL T H+ V AL SL+ L L+Y + LY H D
Sbjct: 99 IPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPGPD 158
Query: 148 NASISQT------------DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVT 195
N +I DY TW AM ++++G K IGVSNFNI +LERL +
Sbjct: 159 NNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARIP 218
Query: 196 PSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQK 255
P+V Q+E++ L Q L+ +CKA GI +VA+ P G + +A P AD A K
Sbjct: 219 PAVNQIELHPYLPQVELVRFCKANGIHLVAHQPLG---GKPVAAVNPNADRP-----ASK 270
Query: 256 YKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQI 291
++++ QI+L ++V+ G+ IPK++ + R+ EN+ +
Sbjct: 271 HERSPAQIILSWIVQQGISVIPKTVRQSRMVENLDL 306
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 141 bits (341), Expect = 3e-32
Identities = 91/270 (33%), Positives = 141/270 (52%), Gaps = 28/270 (10%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
IP G GTW +L+G++ + S AI+ GYRHID AAIY E +VG IK +
Sbjct: 11 IPRLGFGTW------QLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEGIK----DS 60
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTD 155
+ R++LFVTTK+WN + +K A+ +SL L LDYV+L L+HWPI +D Q
Sbjct: 61 GIPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI--NDMPIADQVG 118
Query: 156 YVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDY 215
+ ++ G K IG+SN+N Q S + +Q E + L Q +L
Sbjct: 119 ------PLAEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDPILKT 172
Query: 216 CKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLR-YLVELGVI 274
+ ++ +Y+P G S PA + +A+++ KT QI+LR +L + V
Sbjct: 173 ARGFDMMFTSYSPLGR--GEAMSNPA-------IERLAEQHGKTPAQIILRWHLQQANVA 223
Query: 275 PIPKSLHKDRVEENIQIYDFSLTPDEIQLL 304
IPK+ K +E+N I+DF L+ +++ +
Sbjct: 224 AIPKATSKAHIEQNFDIFDFELSATDMKTI 253
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 141 bits (341), Expect = 3e-32
Identities = 94/302 (31%), Positives = 159/302 (52%), Gaps = 24/302 (7%)
Query: 24 LAPVLKLNNGKEIP-GFGIGT-WLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTE 81
L + +GKEI G GT W + E+ ++ + G+RHIDTA Y+T+
Sbjct: 7 LPKTFRTKSGKEISIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQ 66
Query: 82 DQVGRAIKKKIAEGVVKREDLFVTTKL---WNT-NHKKEAVLPALRKSLKNLDLDYVDLY 137
+VG A+K+ V RED++VTTK W + ++ ++ K+L L +DYVDL+
Sbjct: 67 KEVGEALKRTD----VPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLF 122
Query: 138 LIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVT-- 195
LIH P + + + W+A+ + G + IG+SN I LE+L +
Sbjct: 123 LIHSPFFTTEQTHGYTLE--QAWEALVEAKKAGKVREIGISNAAIPHLEKLFAASPSPEY 180
Query: 196 -PSVLQVEINLNLQQPA--LLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAI 252
P V Q+E + LQ + ++ +C+ GI+V A++P L + +A A + L +
Sbjct: 181 YPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLAPLARVETNALA-----ETLKRL 235
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD--NG 310
A+KYKKT Q++LRY ++ G++P+ S + R++E++ ++DF LT +E+ + N
Sbjct: 236 AEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFDFELTDEEVNEINKIGDANP 295
Query: 311 YR 312
YR
Sbjct: 296 YR 297
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 141 bits (341), Expect = 3e-32
Identities = 100/294 (34%), Positives = 149/294 (50%), Gaps = 47/294 (15%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEW-----------AIDAGYRHI----- 72
KLN G EIP G+GTW K E + + GY +
Sbjct: 15 KLNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALHPLYI 74
Query: 73 -----DTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLK 127
D A IY E++VG+ IK A GV R +LFVTTK+W T H++ L +SL+
Sbjct: 75 PFLAKDAAWIYGNENEVGQGIK---ASGV-PRSELFVTTKIWCTYHRQPEA--CLDESLQ 128
Query: 128 NLDLDYVDLYLIHWPIAL-----------HDNASISQTDYV--ETWQAMTDVLNQGLTKS 174
L LDYVDL L+HWP+ L D + D+ +TW+ M + G TK+
Sbjct: 129 RLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKA 188
Query: 175 IGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFN 234
IGVSN++I L++L ++ + P+ QVE++ L Q L+ YC +GI+ AY+P G
Sbjct: 189 IGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPLG---- 244
Query: 235 RQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEEN 288
S+ P D+R+ +IA+ +K Q+V+ + + GV+ +PKS+ R+E N
Sbjct: 245 ---SSGGPVLQDERVQSIAKAHKADPAQVVISWAAQRGVVALPKSVTPSRIETN 295
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 140 bits (339), Expect = 5e-32
Identities = 91/282 (32%), Positives = 148/282 (52%), Gaps = 26/282 (9%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
IP FG+GT+ L+ V SV A+ GYR IDTA IY E VG+AI+ E
Sbjct: 3 IPVFGLGTF------RLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAIQ----ES 52
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTD 155
+ R++LF+TTK+W N K+ ++P+LR+S++ L DYVDL LIHWP + +D S++
Sbjct: 53 GINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP-SPNDEVSVA--- 108
Query: 156 YVETWQAMTDVLNQGLTKSIGVSNFNIQQLER-LKSEGGVTPSVLQVEINLNLQQPALLD 214
E + GLT+ IG+SNF I +++ + + G + Q+E++ LQ ++D
Sbjct: 109 --EFMSELLKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNRNVVD 166
Query: 215 YCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVI 274
+ K GI V +Y + + + P + IA+++ T Q++L + ++LG
Sbjct: 167 FAKQNGIAVTSYMTLA--YGKALAEPV-------IKTIAEQHGATPAQVILSWAMQLGYG 217
Query: 275 PIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSP 316
IP S + N+ L ++ L+ + D R +SP
Sbjct: 218 VIPSSTKAANLASNLLAQKLCLNAADMALIATLDRNERLVSP 259
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 140 bits (338), Expect = 6e-32
Identities = 92/291 (31%), Positives = 150/291 (51%), Gaps = 30/291 (10%)
Query: 18 LSPSAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAI 77
L+P P L +G +P G+GT+ L D++ SV A+ +GY HIDTA
Sbjct: 27 LNPPRVTIPTQTLPSGDTLPALGLGTYA------LDDDQIADSVRAALSSGYTHIDTAEG 80
Query: 78 YSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLY 137
Y E+ +G + + R+D+F+T+K+ N E+++ + SL+ L+ DY+DLY
Sbjct: 81 YHNEEAIGEVLAE------YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLY 134
Query: 138 LIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPS 197
LIHWP N +IS E+ QAM ++ ++GL +++GVSNF+ QL V +
Sbjct: 135 LIHWP-----NPAISLR---ESLQAMAELHDRGLVRNVGVSNFSAYQLSCANHISEVPIA 186
Query: 198 VLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYK 257
V Q+E + Q+P L+DYC V+ A P A DD+ + +A+ Y
Sbjct: 187 VNQIEFHPWFQRPNLVDYCHESDTVIEAAAPL---------ARTEVFDDEVVAELAESYD 237
Query: 258 KTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
K+ Q++LR+ ++ V+ +P+S + V N + D+ L + Q L D
Sbjct: 238 KSPAQVILRWALDRDVVALPRSSTPEHVRANADL-DWELDAADRQRLDERD 287
>UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG07276.1 - Gibberella zeae PH-1
Length = 284
Score = 139 bits (337), Expect = 8e-32
Identities = 91/273 (33%), Positives = 147/273 (53%), Gaps = 29/273 (10%)
Query: 45 LGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFV 104
+G S +++G+ +V A+ AGYRHID+AA+Y E +V AI++ GV REDLF+
Sbjct: 23 IGFGSYKIRGETCAAAVLAALPAGYRHIDSAALYRNEVRVREAIEQS---GVF-REDLFL 78
Query: 105 TTKLWNTNHKKEA------VLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTDYVE 158
TTK+ + K E V+ A+ + + D YVDL L+H P S+
Sbjct: 79 TTKVGSPRRKTEKTEAYEDVIEAVER-IAGKD-GYVDLLLMHVP-------GPSREHRHS 129
Query: 159 TWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGV-TPSVLQVEINLNLQQPALLDYCK 217
W+AM + ++IGVSNF ++ L+ +K PSV Q+E++ QQ ++ YC+
Sbjct: 130 LWEAMERAKREARARNIGVSNFRVRHLDEMKEYATEWPPSVNQIELHPWCQQKEVVKYCQ 189
Query: 218 AQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIP 277
I++ AY+P A R +D + I+ K+ K+ Q+++RY ++ G +P+P
Sbjct: 190 DNEIIIEAYSPL---------ATGARLEDPLVEGISTKHDKSHAQVLIRYSLQKGWVPLP 240
Query: 278 KSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
KS DR+ EN ++DF L D+++ L D G
Sbjct: 241 KSSRPDRISENFNVFDFVLDEDDMETLDDLDKG 273
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 139 bits (337), Expect = 8e-32
Identities = 95/292 (32%), Positives = 157/292 (53%), Gaps = 29/292 (9%)
Query: 32 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKK 91
N ++P GIGT+ K ++++ ++ ++ GYR IDTA++Y+ E+++G+ + +
Sbjct: 23 NPIKMPMLGIGTF--------KLNDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEM 74
Query: 92 IA--EGV----VKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP--I 143
+ +G+ +KREDLF+T+K E L A SLK L LDY+D YLIHWP
Sbjct: 75 VTKNDGLDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVK 134
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGG--VTPSVLQV 201
L + S + +TW+A+ + +SIGVSN+ I L L S + P++ QV
Sbjct: 135 GLDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQV 194
Query: 202 EIN-LNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTV 260
E + LN Q+ LL++CK I++ +Y G+L A +++ + A+K +T
Sbjct: 195 EFHPLNFQKD-LLEFCKNNKIILESY---GSL------AGGRLLNNESVKEFAKKVGRTP 244
Query: 261 PQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYR 312
Q++LRY +E IPK+ + R+ EN I DF+L+ D + L + R
Sbjct: 245 SQLLLRYCLEHNCPVIPKTENVHRLIENQMILDFTLSDDIVNSLDKLNKDQR 296
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 138 bits (334), Expect = 2e-31
Identities = 103/283 (36%), Positives = 141/283 (49%), Gaps = 19/283 (6%)
Query: 31 NNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKK 90
N IP G+GT+ S +G V+ SV A+ GYRHID A Y V R I
Sbjct: 11 NTSIRIPARGLGTFQVDPSLYPEGS-VKDSVLHALKIGYRHIDAALAYGW-GSVERGIGA 68
Query: 91 KIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLI----HWPIALH 146
I V RED+FV TKL N H E V + SLKNL L YV + +
Sbjct: 69 AIRASGVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYVPYAYTKGENYSTVRKP 128
Query: 147 DNASISQTD----YVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVE 202
D + + + TW+AM ++++QG K IGVSNF+ +L+RL S + P V QVE
Sbjct: 129 DGKPVVDIELSRAFDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVE 188
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFG-----NLFNRQPSAPAPRADDQRLVAIAQKYK 257
+N Q LL +C I V AY P G L R+ P +D + A+A++Y
Sbjct: 189 LNPYFPQKQLLRFCHEHEIHVTAYGPLGCTPVPYLIGRKTPGP---LEDCTVKAMAERYS 245
Query: 258 KTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDE 300
+T QI+L +L+ LGV IPKS + R+ EN L+P++
Sbjct: 246 RTPAQIILAHLIMLGVSVIPKSNNLSRISENFDCL-VELSPED 287
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 138 bits (334), Expect = 2e-31
Identities = 97/299 (32%), Positives = 153/299 (51%), Gaps = 25/299 (8%)
Query: 32 NGKEIP-GFGIGT---WLGTNSNELKGD----EVQKSVEWAIDAGYRHIDTAAIYSTEDQ 83
+GK I G G GT WL E + + E+ S+ A++ GY HIDTA +Y+T +
Sbjct: 19 SGKPITLGTGTGTKWQWLKKGRPEEEQNTLTTELVDSILLALENGYNHIDTAEVYTTHPE 78
Query: 84 VGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPA----LRKSLKNLDLDYVDLYLI 139
V A+KK G+ REDLF+TTK A+ + ++LK L+ DYVDL+LI
Sbjct: 79 VAAAVKKS---GIA-REDLFITTKYTPGFRTFPAISSGPTEFIDRALKELETDYVDLFLI 134
Query: 140 HWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGG---VTP 196
H P + S QT W + D G + IGVSNF+ + LER G P
Sbjct: 135 HSPF-FEEKVSRGQT-LESAWAEVIDAKKAGKVRHIGVSNFSKEHLERTFKVAGNPDFYP 192
Query: 197 SVLQVEIN--LNLQQPALLDYCKAQGIVVVAYTPFGNLFN-RQPSAPAPRADDQRLVA-I 252
V Q+E + L Q P ++ + + I++ AY P LF +Q + L+ +
Sbjct: 193 KVNQIEFHPYLQNQSPGIIKFAQENDILIEAYGPLSTLFRIKQNGVDVEDHPLKELIPKL 252
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGY 311
A+KY KT QI+LRY ++ ++PI S DR+ +++++Y+F ++ +++ + + Y
Sbjct: 253 AEKYGKTDAQILLRYTLQKKILPITTSSKLDRIRQSLEVYNFEISDEDVAEIDKTGSSY 311
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 137 bits (332), Expect = 3e-31
Identities = 93/287 (32%), Positives = 146/287 (50%), Gaps = 28/287 (9%)
Query: 33 GKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKI 92
G +P G+GT+ ++G + +VE A+ GYRHIDTA +Y+ ED +G A+
Sbjct: 8 GVRLPKLGLGTF------RMQGTVCRDAVESALALGYRHIDTAEMYANEDAIGAAL---- 57
Query: 93 AEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASIS 152
A + REDL VTTK+W N +A+ A SLK L LD+VDLYLIHWP ++
Sbjct: 58 AAAQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPA-----TGMN 112
Query: 153 QTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPAL 212
+ET A+ +G T++IGV+NF + L++ + + QVE ++ L Q L
Sbjct: 113 LPAAMETLMALK---QEGRTRAIGVANFTVALLKQAVEDIQAPVACNQVEYHVMLDQSKL 169
Query: 213 LDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVEL- 271
+ Y K++ I +VAY P A A D+ L I +K+ Q+ L++L++
Sbjct: 170 MAYMKSRSIPLVAYCPL---------AQGRAAGDETLAGIGRKHGAGAAQVALKWLLDQD 220
Query: 272 GVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLF 318
GV IPK+ + + N L ++ + + R ++P F
Sbjct: 221 GVAAIPKAARPESQQANWDAMKVQLDDEDRATIAALPKDKRFVNPGF 267
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 136 bits (330), Expect = 6e-31
Identities = 73/171 (42%), Positives = 99/171 (57%), Gaps = 7/171 (4%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+KLNNG IP FG GT+ + NE SV A+ GYRHIDTAA Y E V A
Sbjct: 8 IKLNNGTAIPMFGYGTYKIKDQNE-----AYNSVRLALKNGYRHIDTAAFYENEKFVANA 62
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
IK + E KRED+FVT+K W T + L A K++ + +DY+DLYL+HWP +
Sbjct: 63 IKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAF 122
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
+ T+ +TW+AMT++ G K+IGVSNF L+ + + VTP+V
Sbjct: 123 DDDWENTNR-QTWKAMTEIYKSGRVKAIGVSNFLTHHLDTI-IDMEVTPAV 171
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 136 bits (329), Expect = 7e-31
Identities = 89/266 (33%), Positives = 133/266 (50%), Gaps = 27/266 (10%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
+P G GTW +L+ VE A++ GYRHIDTA IY E VG AI+
Sbjct: 15 MPALGFGTW------QLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAAIRNS---- 64
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTD 155
VKR+++F+TTK+W + + KSL+ L +D VDL L+HWP +
Sbjct: 65 GVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLHWPKP--------EVP 116
Query: 156 YVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDY 215
ET +A+ V +G T++IG+SNF QLE + QVE + L L
Sbjct: 117 LAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQVEYHPYLSLKTLKAK 176
Query: 216 CKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIP 275
G+ + A++P A A D L+ I + + KT Q+ LR++++ G+I
Sbjct: 177 ADQLGVSITAWSPL---------AQGKVAQDPVLIEIGRAHGKTPGQVTLRWIIQQGIIA 227
Query: 276 IPKSLHKDRVEENIQIYDFSLTPDEI 301
IP++ + R+EEN I DF L+ E+
Sbjct: 228 IPRTSNPKRIEENFDILDFELSEKEM 253
>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
reductase; n=5; Pezizomycotina|Rep: Related to 2,
5-diketo-D-gluconic acid reductase - Neurospora crassa
Length = 289
Score = 135 bits (327), Expect = 1e-30
Identities = 87/286 (30%), Positives = 148/286 (51%), Gaps = 27/286 (9%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+KL+NG IP +G ++ + G E ++V WA+ AGYR D+A Y E + G+A
Sbjct: 13 VKLSNGLSIPQIQLGLYM------MSGPETTRAVRWALGAGYRGFDSAQWYYNEREAGQA 66
Query: 88 IKKKIAE----GVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPI 143
I ++ + R+D+ T+KL + + +AV ++ KS+K L Y+DL+L+H P+
Sbjct: 67 ILSFLSSPENTAGLTRKDVHFTSKLRDNSTNYDAVRASISKSVKASGLGYIDLFLLHSPL 126
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEG-GVTPSVLQVE 202
+ + +W+A+ D + G K GVSN+ ++ L+ + S + P V Q+E
Sbjct: 127 G-------GREARLTSWKAVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPFKIKPLVNQIE 179
Query: 203 INLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQ 262
+ QP + C+ GIV+ AY P A R L A+A+KY T Q
Sbjct: 180 CHPFNTQPEIRAACEKYGIVIEAYAPL---------ARGMRMKHPVLTAVAKKYGVTPAQ 230
Query: 263 IVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
+++R+ V+ G + +PKS K+R+ EN + F L ++++ L D
Sbjct: 231 VLVRWSVQHGFVTLPKSTKKERLVENADVGRFELAEEDMEKLDGLD 276
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 135 bits (327), Expect = 1e-30
Identities = 93/268 (34%), Positives = 145/268 (54%), Gaps = 28/268 (10%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
+L NG +P G+GT+ G + NE +V+ V+ AI AGYRHID AA Y E+ +G AI
Sbjct: 9 RLVNGSTLPAIGLGTFQGDDGNE----KVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDAI 64
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDN 148
K E + R++L + W H+ + V AL SL+ L L+YV + P +N
Sbjct: 65 K----ESGISRDEL---AQPW---HEPKDVERALDLSLEALGLEYVPHAYLPGP----NN 110
Query: 149 ASISQT-DYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
++ Y ETWQAM +++ G K+IG+SNFNI + +R+ + P+V QVE +
Sbjct: 111 VDYERSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAHPYF 170
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRAD------DQRLVAIAQKYKKTVP 261
Q LL +C+ + I ++A+ P G + AP AD D ++ IA + T
Sbjct: 171 PQHELLAFCEKEHIHLMAHQPLG---GKPVGVVAPHADIPGPLFDTKIAQIAAQTGMTPA 227
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENI 289
Q++L + V+ G IPK+ ++ R+ EN+
Sbjct: 228 QVILSWAVQRGTSIIPKTSNESRLSENL 255
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 135 bits (326), Expect = 2e-30
Identities = 90/265 (33%), Positives = 139/265 (52%), Gaps = 27/265 (10%)
Query: 32 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKK 91
+G IP G G + + EV++ + A++AG+RH DTA IY E +GRA+++
Sbjct: 7 HGATIPALGFGVF------RMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRALERA 60
Query: 92 IAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASI 151
A +REDLF+TTK+W N+ + ++ +SL+ L +D VDL L+HWP H+
Sbjct: 61 GA----RREDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP--AHEVPVA 114
Query: 152 SQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPA 211
+Q +E A+ D G T+ IGVSN NI Q+ + QVE++ L Q +
Sbjct: 115 AQ---IERLNAVKDA---GKTRFIGVSNQNIAQMRESIARSAAPIVTNQVELHPYLPQHS 168
Query: 212 LLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVEL 271
L+ + + V AY +G P P L I +Y K+ Q+ LR+LV+
Sbjct: 169 LVAAARDSAVAVTAY--YGMADGAVPKDPV-------LQQIGARYGKSAAQVGLRWLVQQ 219
Query: 272 GVIPIPKSLHKDRVEENIQIYDFSL 296
G + + K+ + RV ENI I+DF+L
Sbjct: 220 GYVALSKTANPARVAENIAIFDFAL 244
>UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 326
Score = 135 bits (326), Expect = 2e-30
Identities = 92/293 (31%), Positives = 148/293 (50%), Gaps = 39/293 (13%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
L++N+G EIP G G + + + + V A DAGYRH+D+AA Y E A
Sbjct: 46 LRMNSGYEIPILGYGVY------QTPASQCEDLVAKAFDAGYRHVDSAAAYRNEGPCAAA 99
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
I++ + RED+F T+K+ + E + K+L L Y+DL LIH P
Sbjct: 100 IRRSS----IPREDIFFTSKIPPRSLSYENTKAQVAKTLMETGLGYIDLMLIHAPYG--- 152
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQL------------ERLKSEGGVT 195
+ W+A+ + +G +S+GVSN+ + L ER K GGV
Sbjct: 153 ----GRAARKGAWKALVEAQEEGKIRSLGVSNYGVHHLDEMEVYMKELEEERGKGRGGVI 208
Query: 196 PSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQK 255
V Q E++ L + ++ +C+ +GIV AY+P R D + L + +K
Sbjct: 209 -DVGQWELHPWLARSDIISWCQQRGIVAEAYSPL---------IRGERHDSKLLQPLTKK 258
Query: 256 YKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
Y KT QI+LR+ ++ G +P+PK++ R++EN I+DF LT +E++ L++ D
Sbjct: 259 YNKTPAQILLRWSLQKGFVPLPKTVTPGRIKENADIFDFELTAEEMEGLETGD 311
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 134 bits (325), Expect = 2e-30
Identities = 87/257 (33%), Positives = 136/257 (52%), Gaps = 29/257 (11%)
Query: 40 GIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKR 99
G+GTW ++ GD VQKSV ++ GY H+DTA Y E ++G A+ R
Sbjct: 3 GVGTW------DIDGDTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD------YDR 50
Query: 100 EDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTDYVET 159
ED+F+T+K+ + E+V+ A SL L DY+DLYL+HWP N + T ET
Sbjct: 51 EDVFLTSKVLPKHLDYESVIEACEASLDRLGTDYLDLYLVHWP-----NPA---TSIRET 102
Query: 160 WQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQ 219
AM + +QG +++GVSNF+ QL + V +V Q+E + Q ++++C+
Sbjct: 103 MNAMATLHDQGKIRNVGVSNFSAYQLGAAQHVADVPIAVNQIEYHPWNTQDQVVEFCRDT 162
Query: 220 GIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKS 279
VV A P G ADD + +++KY ++ QIVL++ VE V+ +PKS
Sbjct: 163 DTVVEAAAPLGR--------TKVFADD-IIQDLSEKYDRSPAQIVLKWAVENNVVVLPKS 213
Query: 280 LHKDRVEENIQIYDFSL 296
+ V +N ++D+ L
Sbjct: 214 SSPEHVRQNFDLFDWEL 230
>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
pacificus|Rep: Aldose reductase - Pristionchus pacificus
Length = 293
Score = 133 bits (322), Expect = 5e-30
Identities = 85/275 (30%), Positives = 142/275 (51%), Gaps = 12/275 (4%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
+P G+GT+ + + L +++ A GYR IDTA IY E +GR + + +
Sbjct: 16 MPMIGVGTYQVQSQSVLTD-----TIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKH 70
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP--IALHDNASISQ 153
+KRED+F+T+K+ N K ++ KSL +L Y+DL LIHWP L N +
Sbjct: 71 SLKREDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGTSRLKSNHKDNA 130
Query: 154 TDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALL 213
ET+ + ++++G +SIGVSN+ I+ LE L +E + P++ Q E + + + L
Sbjct: 131 KFRAETYVELETLMDEGKIRSIGVSNYEIKHLETLLAECRILPAINQCECHPHFRNSELA 190
Query: 214 DYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGV 273
+YCK +GI AY+ G PS D+ + IA + + I+L + + G
Sbjct: 191 EYCKEKGIHFQAYSSLGG-----PSYVENLLKDKIIKKIANAHSTSPAVILLAWGLNQGY 245
Query: 274 IPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
+P++ R+EEN + D L+ E++ + S D
Sbjct: 246 SILPRTEKVGRIEENWKAKDIKLSEKEMKEIGSID 280
>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 287
Score = 133 bits (322), Expect = 5e-30
Identities = 83/287 (28%), Positives = 148/287 (51%), Gaps = 19/287 (6%)
Query: 27 VLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGR 86
+ KL NG+EIP +GT+ E KGD++ +V+ A+ GYR DTA Y E +G
Sbjct: 1 MFKLKNGQEIPKLALGTY------EAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGL 54
Query: 87 AIKKKIAEGVVKREDLFVTTKL--WNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIA 144
A+K + + ED+++T+K+ +++ + E + + +SL+ LD Y+DL L+H+P
Sbjct: 55 ALKTLLPRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRP 114
Query: 145 LHDNASISQTDYV---ETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQV 201
L D +++ + + +TW A+ + +G +SIGVSN+ +E ++S + P V Q+
Sbjct: 115 L-DTEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQI 173
Query: 202 EINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVP 261
E + + Q+ L YC I+ A++P G D + IA +K TV
Sbjct: 174 EYHPHFQRKVLRAYCNKNEILFQAFSPLGR-------GNKTLLGDSTMERIALCHKTTVA 226
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
++L ++++ + KS+ RV EN L+ DE + + +
Sbjct: 227 NVILAWIMKGKYGVVAKSVTPSRVAENYTSLSLELSDDEFEKINGLN 273
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 133 bits (321), Expect = 7e-30
Identities = 84/283 (29%), Positives = 152/283 (53%), Gaps = 26/283 (9%)
Query: 26 PVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVG 85
P+L LN+G +IP G+GT L + +++ A++ G R DTA++Y E +VG
Sbjct: 35 PLLTLNDGYQIPIIGLGT------TSLHNQTCKNAIKAALEIGIRLFDTASLYGNEKEVG 88
Query: 86 RAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL 145
I+ E + R ++FV TKL+ A+ ++L L+ DY+D+ L+H P
Sbjct: 89 ETIR----ESNINRNEIFVITKLYPGAQFANPE-KAIEEALNKLNTDYIDMMLLHHP--- 140
Query: 146 HDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINL 205
+ D V+ ++A+ + +G KS+G+SN+ I+++ + + PS++Q EI++
Sbjct: 141 ------GEND-VKAYKAIEKYIEKGKIKSVGLSNWYIKEINSFLPQINIKPSLIQNEIHI 193
Query: 206 NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL 265
Q+ ++ Y I + A+ PFG + P +V+IA+ + KT QI+
Sbjct: 194 YYQEKEVVPYMHNLNIAMQAWYPFGGRGHTFSVLNNPT-----IVSIAKDHNKTSAQIIS 248
Query: 266 RYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFD 308
R+L++ G+I I S + ++ENI ++DF L+ E++L+ S D
Sbjct: 249 RWLLQRGIITIVGSSNPIHIKENISVFDFELSNQEMELIASLD 291
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 132 bits (320), Expect = 9e-30
Identities = 90/301 (29%), Positives = 149/301 (49%), Gaps = 23/301 (7%)
Query: 30 LNNGKEIPGFGIGTWLGTNSNELKGDEVQKS-----VEWAIDA----GYRHIDTAAIYST 80
LNNG +IP I +GT + K +E + VE + A G HID A IY T
Sbjct: 10 LNNGNKIPAIAI---IGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRT 66
Query: 81 EDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIH 140
+VG+A+ + E R +F+T K ++ L +LK + DYVDLYL+H
Sbjct: 67 YPEVGKALS--LTEK--PRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLH 122
Query: 141 WPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQ 200
P + ++ E W+ M + G K+IGVSNF ++ L+R+ V P V Q
Sbjct: 123 SPFV---SKEVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQ 179
Query: 201 VEIN--LNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKK 258
+E + L Q P + +C+ I+V AY+P G L ++ + + + + +++KY K
Sbjct: 180 IEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPL-QKKTAQDDSQPFFEYVKELSEKYIK 238
Query: 259 TVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLF 318
+ QI+LR++ + GV+P+ S R+ + ++ F LT +E+ + + L L+
Sbjct: 239 SEAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSFDLTAEEVDKITELGLEHEPLR-LY 297
Query: 319 W 319
W
Sbjct: 298 W 298
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 132 bits (319), Expect = 1e-29
Identities = 91/275 (33%), Positives = 144/275 (52%), Gaps = 29/275 (10%)
Query: 27 VLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGR 86
++ LNNG +IP G G + ++ +E V+ AI GYR IDTA Y E + G
Sbjct: 8 LITLNNGNKIPSIGFGVF------QIPKEETADCVKKAISIGYRLIDTAQAYHNEKETGL 61
Query: 87 AIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALH 146
IK GV KRE++F+TTK+W +N+ E ++ +SLK LD Y+DL L+H P
Sbjct: 62 GIK---LSGV-KREEIFLTTKVWVSNY--ERCYESVIESLKRLDTSYLDLILLHQPFG-- 113
Query: 147 DNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLN 206
+Y + +Q + + + ++IGVSNF ++ L + P V Q+EIN
Sbjct: 114 --------NYYKAYQDLERLYKENKVRNIGVSNFWDNRIIDLCFFNQIKPMVNQIEINPF 165
Query: 207 LQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLR 266
Q+ Y +V A+ PF N + P LV I +KY KT Q++LR
Sbjct: 166 HQRIEDRFYNDKYKVVSQAWAPFAEGKNGLFTNPT-------LVEIGKKYNKTPAQVILR 218
Query: 267 YLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEI 301
+LV+ V+ + K++++ R++EN I+DF L+ ++
Sbjct: 219 WLVQSNVVALCKTVNESRMKENFDIFDFELSKQDL 253
>UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2;
Oceanicola granulosus HTCC2516|Rep:
2,5-didehydrogluconate reductase - Oceanicola granulosus
HTCC2516
Length = 275
Score = 132 bits (319), Expect = 1e-29
Identities = 89/282 (31%), Positives = 139/282 (49%), Gaps = 26/282 (9%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
+PG G GT+ +G++ ++ A++ GYRH+DTA Y TE +VG AI++
Sbjct: 12 MPGLGFGTY------GRQGEDGISAILCALETGYRHLDTAQDYDTEAEVGEAIRR----A 61
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTD 155
+ RE LFVTTK+ N ++P++ +SL+ + LD DL LIHWP N +D
Sbjct: 62 GLPREALFVTTKVRPANFGPGDLVPSVARSLETMGLDRADLVLIHWPA---PNGERPLSD 118
Query: 156 YVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVL-QVEINLNLQQPALLD 214
Y+ + + QGLT+ +GVSNF + L ++ G P + QVE+N + L D
Sbjct: 119 YI---PQLAEARAQGLTRHVGVSNFPVALLTEARALLGDVPILTNQVELNPWFRNRTLAD 175
Query: 215 YCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVI 274
+C GI V Y QP A D + IA ++ T Q+ L + + G
Sbjct: 176 HCMGAGIRVTCY---------QPIAQGRLGGDPVIARIAARHGATPEQVALAWELAQGYA 226
Query: 275 PIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSP 316
IP S + + N Q L+P E+ + + + G R++ P
Sbjct: 227 AIPTSSRPEHIRGNWQAQQLDLSPGELAEIDALNRGRRSIDP 268
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 132 bits (319), Expect = 1e-29
Identities = 92/295 (31%), Positives = 156/295 (52%), Gaps = 28/295 (9%)
Query: 24 LAPVLKLNNGKEIP--GFGIGT--WLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYS 79
L P LKL++G EIP G+G+GT + +S + + + + A++AGY H+D A +Y
Sbjct: 23 LIPSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYG 82
Query: 80 TEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLI 139
E ++GRA IA+ + R L++TTK + V + +SL+ L LDYVDLYL+
Sbjct: 83 NEVELGRA----IAQSKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLL 136
Query: 140 HWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERL-KSEGGV--TP 196
H P + + W+ M + + G+ KSIGVSNF I L+ L GG+ P
Sbjct: 137 HSPFFAKNPEQLQ-----AAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPGGLQYPP 191
Query: 197 SVLQVEINLNLQQPA----LLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAI 252
V Q+E + LQ L+ +C+ + I + AY+P + +P P D +
Sbjct: 192 VVNQIEYHPYLQHVVEGEDLVAFCREKHIAIAAYSPLTAITKARP-GPV----DPIYTQL 246
Query: 253 AQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENI-QIYDFSLTPDEIQLLKS 306
A+KY + +I R+ ++ G++ + S +++R++ + ++ F LTP E++ + S
Sbjct: 247 AKKYGVSEAEIAFRWCLDQGIVTLTTSSNEERLKGYLKKLPSFKLTPKEVEDIAS 301
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 130 bits (314), Expect = 5e-29
Identities = 84/283 (29%), Positives = 148/283 (52%), Gaps = 29/283 (10%)
Query: 28 LKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRA 87
+ LNNG IP G+GT+L L+ D+ Q +V +A+D Y IDTA +Y E VGR
Sbjct: 4 ITLNNGITIPQVGLGTYL------LEPDDAQSAVTYALDNDYTLIDTANVYVNERAVGRG 57
Query: 88 IKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHD 147
++ R+++F+ TKLW + ++ + A+ ++L+ L DY+DL ++H P
Sbjct: 58 MRASSKA----RDEIFLETKLWPSFFERAS---AVEETLERLGTDYIDLMILHQPAG--- 107
Query: 148 NASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNL 207
D V ++ + +G ++IG+SNF++ Q +R+ E V P++ QVE +
Sbjct: 108 -------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVECHPYF 160
Query: 208 QQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRY 267
Q L K I + A+ P G N + + + +A+++ K+ Q++LR+
Sbjct: 161 PQTELKALLKDHNITLQAWYPLGGRGNDSIMS------EPIVQGLAEEHSKSPAQVLLRW 214
Query: 268 LVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNG 310
++ G I IP S + +NI ++DF+LT +++ + S D G
Sbjct: 215 HIQQGHIVIPGSKTPSHIAQNIDLFDFALTDEDMAQIDSLDKG 257
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 130 bits (314), Expect = 5e-29
Identities = 93/302 (30%), Positives = 151/302 (50%), Gaps = 39/302 (12%)
Query: 21 SAGLAPVLKLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYST 80
SA +AP + N +P G GT+ G + +V+ A+D GY HIDTA Y
Sbjct: 7 SADMAP--EQNGTTTVPTLGFGTY------RTGGYKCYNAVKNALDCGYTHIDTAMAYEN 58
Query: 81 EDQVGRAIKKKIAEGVVKREDLFVTTKL--WNTNHKKEAVLPALRKSLKNLDLDYVDLYL 138
E VGRAI+ + V RED+F+TTK+ + + E ++ A + L+ L +Y+DL L
Sbjct: 59 EAAVGRAIE----QSSVDREDIFLTTKIKGYPEMVEYERLIEAAKGCLERLGTEYLDLLL 114
Query: 139 IHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSV 198
+HW L D ET+ A+ +++ GL IGVSNF+I++L++ +
Sbjct: 115 VHWWNPL--------ADMEETFNALNTLVDDGLVGQIGVSNFSIKELKQAMRLSDAPIAT 166
Query: 199 LQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKK 258
Q+E + L+ +C+ + V AY+P A +D L +I +Y K
Sbjct: 167 NQIEYHPYWGDEELVRFCQDNDVTVTAYSPL---------AEGRAVEDDVLRSIGDRYGK 217
Query: 259 TVPQIVLRYLVEL-GVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPL 317
+ Q+ +R+L++ V+ IPK+ +E NI ++DF LT +++ + R L P
Sbjct: 218 SAAQVSIRWLIQQENVVTIPKAATPKHIEANIDVFDFELTDRDMRRI-------RKLKPP 270
Query: 318 FW 319
FW
Sbjct: 271 FW 272
>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
baltica OS145|Rep: Aldo/keto reductase - Idiomarina
baltica OS145
Length = 263
Score = 130 bits (313), Expect = 6e-29
Identities = 90/284 (31%), Positives = 133/284 (46%), Gaps = 28/284 (9%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
IP FG+GT+ L+G E+ V AID GY HIDTA Y E VG+A+ +
Sbjct: 2 IPQFGMGTF------RLEGQELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQHT--- 52
Query: 96 VVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQTD 155
+D+FVTTK+W + VL +L+ S L D +DL LIHWP + +D +
Sbjct: 53 ---NKDVFVTTKVWYEKLAYQDVLDSLQVSRDKLQRDTIDLALIHWP-SPNDEVPVE--- 105
Query: 156 YVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVL-QVEINLNLQQPALLD 214
ET A+ GL K +GVSNF I L R + G + Q+E++ Q A+ D
Sbjct: 106 --ETLDALQKAQQDGLIKHLGVSNFTIDLLNRAAAHVGKDEILTNQIEVHPFFQNHAITD 163
Query: 215 YCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLVELGVI 274
CK G+ V AY P A D+ + IA+K+ + Q+ + + + I
Sbjct: 164 ACKQMGVKVTAYLPL---------AKGAVMDNSVMQNIAEKHNVSPAQVAIAWQLANDYI 214
Query: 275 PIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDNGYRTLSPLF 318
IP + D ++ N L D+++ + D R + P F
Sbjct: 215 AIPSTTKVDHLKSNFDAQSLKLDQDDMKAIADIDKDDRLIDPDF 258
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 128 bits (310), Expect = 1e-28
Identities = 92/280 (32%), Positives = 142/280 (50%), Gaps = 21/280 (7%)
Query: 26 PVLKLNNGKEIP--GFGIGT-WLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTED 82
P L L +G +P GFG GT W + N+ E+ + ++ A++ G+ HID A Y TE
Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63
Query: 83 QVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLIHWP 142
+VG AI+ E + RE LF+TTK+ + V AL SL+ L LDYVDLYL+H P
Sbjct: 64 EVGIAIR----ESGIPREQLFITTKVLEG---WKDVPGALDASLERLQLDYVDLYLLHNP 116
Query: 143 IALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVE 202
+ + TD W+ + V G +SIGVSNF LE + V P++ Q+E
Sbjct: 117 YVIPN-----LTDIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAINQLE 171
Query: 203 INLNLQQP-ALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVP 261
+ LQ+ + + + +GI V + F L P D+ L +IA K+ T
Sbjct: 172 YHPYLQRSHDFIPWMRERGIEV---SSFKTLAPVTVGKGGPL--DEPLASIAAKHNITTS 226
Query: 262 QIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEI 301
+VL +++ ++PI + ++R+EE I L +E+
Sbjct: 227 AVVLNWVISQNIVPITTTTKRERMEEYIAAISLQLDREEL 266
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 127 bits (307), Expect = 3e-28
Identities = 95/290 (32%), Positives = 151/290 (52%), Gaps = 32/290 (11%)
Query: 26 PVLKLNNGKEIPGFGIGTWL--GTNSNELKGDEVQ-KSVEWAIDAGYRHIDTAAIYS--- 79
P L NG IP G GTW G ++ + D+ ++ I G HIDTA +Y+
Sbjct: 5 PWKSLKNGFAIPVLGQGTWRMGGVDTPDTANDDADIAAIRRGIATGLCHIDTAEMYAGGH 64
Query: 80 TEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALRKSLKNLDLDYVDLYLI 139
E+ VG A+K +G+ +R D F+T K+W T+ + + VL A SLK L DY+DLYLI
Sbjct: 65 AEELVGIAMK---GQGI-RRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDLYLI 120
Query: 140 HWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVL 199
H N + + ET +AM + +G+ + IGVSNF+ ++L+R ++
Sbjct: 121 H-----QVNPDVPEE---ETIRAMNRLKREGVIRHIGVSNFSEERLKRAQAASDAPIVAN 172
Query: 200 QVEINL---NLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKY 256
Q+ NL ++Q LLDYC++Q I+V+A+ P L P +V +A+KY
Sbjct: 173 QLHYNLRIREIEQCGLLDYCRSQDIMVIAWRPLRGLDLALP----------LIVTLAEKY 222
Query: 257 KKTVPQIVLRYLV-ELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLK 305
KT QI L +L+ + V+ I K+ + + EN+ + L ++ + L+
Sbjct: 223 GKTPSQIALNWLLCQENVVTITKAANPLHLAENMGALGWVLEKEDAERLR 272
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 127 bits (307), Expect = 3e-28
Identities = 83/266 (31%), Positives = 132/266 (49%), Gaps = 23/266 (8%)
Query: 56 EVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGV--VKREDLFVTTKLWNTNH 113
E +++ A+ GYRH D A Y E +G K+ + VKREDL++ +KLW H
Sbjct: 16 EDPEAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWPNFH 75
Query: 114 KKEAVLPALRKSLKNLDLDYVDLYLIHWPIAL-----HDNAS--------ISQTDYVETW 160
+ E V + ++L++L L+Y+D++L+HWP+A+ D AS + T +TW
Sbjct: 76 EPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKGGTLLGTTPIRKTW 135
Query: 161 QAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQG 220
+AM +++ T+ IGVSN L L S + P Q E L+++C + G
Sbjct: 136 EAMEACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNG 195
Query: 221 IVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVL-----RYLVELGVIP 275
I V AY P G AP D L +A+K TV +++L R+
Sbjct: 196 IYVTAYRPLGGRCRVDAKAP---LTDPALEELAKKANLTVSELILAWHWTRWGTSGTYSV 252
Query: 276 IPKSLHKDRVEENIQIYDFSLTPDEI 301
IPKS ++R ++N++ LTPD++
Sbjct: 253 IPKSSDRERQKQNLESVKLRLTPDQM 278
>UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Bacteroides fragilis|Rep: 2,5-diketo-D-gluconic acid
reductase - Bacteroides fragilis
Length = 298
Score = 127 bits (306), Expect = 5e-28
Identities = 90/305 (29%), Positives = 155/305 (50%), Gaps = 45/305 (14%)
Query: 32 NGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKK 91
NG ++P G+GT+ L+G+ + A GYR IDTA Y E +G A+ +
Sbjct: 8 NGHDVPMVGLGTY------PLQGEAMASMALDAFKCGYRLIDTADDYRGETGLGLALSRL 61
Query: 92 IAEGVVKREDLFVTTKL--------------W--------NTNHKKEAVLPALRKSLKNL 129
E +RED+F+ TK+ W N + +E V+ + SL+ L
Sbjct: 62 NNETGFRREDVFIQTKISQDNAYGDEPLEGVWFNKLSKYQNRHTVEEVVMDKVTISLREL 121
Query: 130 DLDYVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLK 189
DY+D LIH+P + Y + W M + +G + IGVSNF+I LE+LK
Sbjct: 122 QTDYIDSLLIHYPFPGY---------YEDIWDVMMRLKKEGKVRYIGVSNFHINHLEKLK 172
Query: 190 SEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRL 249
S G PS+ Q+ ++ + L+Y I ++ Y+P +L + Q +D L
Sbjct: 173 SI-GECPSINQIYVSPLSIKHEDLEYSINNAIQLMTYSPLMDLVHGQ-------LNDNIL 224
Query: 250 VAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKSFDN 309
+ +A+KY+KT Q++LR+ ++ G +P+P++ + +R+ N +++DF LT +EI+ + + +
Sbjct: 225 MPLAEKYRKTKHQVILRWNIDRGCMPLPRTTNPNRLLGNFELFDFKLTEEEIEAISAMNR 284
Query: 310 GYRTL 314
+ L
Sbjct: 285 DLQFL 289
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 127 bits (306), Expect = 5e-28
Identities = 93/276 (33%), Positives = 145/276 (52%), Gaps = 34/276 (12%)
Query: 36 IPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEG 95
IP G+GTW T G + V + GY HIDTA Y E +VG+ IK+ G
Sbjct: 16 IPVLGLGTWQST------GQDCIDVVSQGLRMGYEHIDTAQAYGNEVEVGKGIKQS---G 66
Query: 96 VVKREDLFVTTKLWNTNHK--KEAVLPALRKSLKNLDLDYVDLYLIHWPIALHDNASISQ 153
V R+ F+TTK++ + K E ++ A ++SL+NLD DYVDL L+HWP D +S
Sbjct: 67 VA-RDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP---DDRVPLS- 121
Query: 154 TDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEINLNLQQPALL 213
ET A+ ++ QGLT++IGVSNFNI + K V V QVE + ++Q L
Sbjct: 122 ----ETIPALCELQKQGLTRNIGVSNFNIANIIEAKRYADVPIVVNQVEFHPFIKQKTLQ 177
Query: 214 DYCKAQGIVVVAYTPF--GNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQIVLRYLV-E 270
+ I++ AY+P G++F D++ + IA K+ T Q+ L +++ +
Sbjct: 178 TFLNNHHILLEAYSPLARGDVF-----------DNKIIKDIADKHGITAAQVSLAWILSD 226
Query: 271 LGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQLLKS 306
I IPK+ + + ++ N+ L+ DE++ + S
Sbjct: 227 KHRIAIPKTSNPEHLQGNLDAIKVELSADELEKIGS 262
>UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 263
Score = 126 bits (305), Expect = 6e-28
Identities = 82/253 (32%), Positives = 133/253 (52%), Gaps = 19/253 (7%)
Query: 64 AIDAGYRHIDTAAIYSTEDQVGRAIKKKIAEGVVKREDLFVTTKLWNTNHKKEAVLPALR 123
A+ GY+ IDTA +Y E+ VGRAIKK + +RED+ + TK+W + + A+
Sbjct: 24 ALQNGYKIIDTAKVYQNEEIVGRAIKKYLNSNNQRREDIIIETKIWCDDVEAGNTTNAVL 83
Query: 124 KSLKNLDLDYVDLYLIHWPIALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQ 183
+SLK L++ Y+D+ LIH P N + +T ++ + + +GL +GVSNF+
Sbjct: 84 ESLKRLNVTYLDIVLIHRP-----NLNFYKT--IKAYVELLQCKAKGLINVVGVSNFDKD 136
Query: 184 QLERLKSEGGVTPSVLQVEINLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPR 243
+E L E G P++ Q+E N Q+ + YC+ + I+V +Y+P N
Sbjct: 137 MIEILFEETGAYPNLNQIEFNPFNQRWDRVQYCQNKNILVQSYSPIANTL---------- 186
Query: 244 ADDQRLVAIAQKYKKTVPQIVLRYLVELGVIPIPKSLHKDRVEENIQIYDFSLTPDEIQL 303
++Q L A+KY TV Q++L ++ + PI K+ ++EN Q LT IQ+
Sbjct: 187 -ENQTLATEAKKYNCTVAQLILAWIQYFSIQPIVKAELLRHIQENKQSEKIRLTKKTIQI 245
Query: 304 LKSFDNGYRTLSP 316
L+S N Y + P
Sbjct: 246 LQSL-NMYDNIYP 257
>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 301
Score = 126 bits (305), Expect = 6e-28
Identities = 89/288 (30%), Positives = 136/288 (47%), Gaps = 18/288 (6%)
Query: 29 KLNNGKEIPGFGIGTWLGTNSNELKGDEVQKSVEWAIDAGYRHIDTAAIYSTEDQVGRAI 88
K ++G E+P G LG + E + D + S+E A+ +GYR DTA +Y E +G ++
Sbjct: 13 KFSDGYEMPKIG----LGISRIETQQD-LDVSIEAALKSGYRQFDTANLYKNETFLGNSL 67
Query: 89 KKKIAEGVVKREDLFVTTKLWNTNHKK-EAVLPALRKSLKNLDLDYVDLYLIHWP----I 143
KK + + + RED+F+TTK+ N E L SL L DYVDL LIH+P
Sbjct: 68 KKYLPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRDRDT 127
Query: 144 ALHDNASISQTDYVETWQAMTDVLNQGLTKSIGVSNFNIQQLERLKSEGGVTPSVLQVEI 203
D+ I+++ WQ + G +SIGVSN+ + L + + P + Q E
Sbjct: 128 GNDDDYEINKSRRKIVWQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQYEY 187
Query: 204 NLNLQQPALLDYCKAQGIVVVAYTPFGNLFNRQPSAPAPRADDQRLVAIAQKYKKTVPQI 263
L +P L +C IVV +Y+ ++ LV + QKY +T I
Sbjct: 188 QPYLTRPTLKKFCDLNNIVVQSYSSL-------CWGDKEILQEKPLVDLCQKYNQTPQAI 240
Query: 264 VLRYLVELGVIPIPKSLHKDRVEENI-QIYDFSLTPDEIQLLKSFDNG 310
+ + IPKS R+ +N+ LT DE++ L+S D G
Sbjct: 241 LYAFAHCSNTSMIPKSATPSRIHDNLHNTIKIKLTEDELKSLRSLDKG 288
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.136 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 386,666,177
Number of Sequences: 1657284
Number of extensions: 16762183
Number of successful extensions: 42147
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 414
Number of HSP's successfully gapped in prelim test: 380
Number of HSP's that attempted gapping in prelim test: 40139
Number of HSP's gapped (non-prelim): 955
length of query: 331
length of database: 575,637,011
effective HSP length: 101
effective length of query: 230
effective length of database: 408,251,327
effective search space: 93897805210
effective search space used: 93897805210
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 73 (33.5 bits)
- SilkBase 1999-2023 -