Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001351-TA|BGIBMGA001351-PA|IPR001395|Aldo/keto reductase
(340 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 279 7e-74
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 264 2e-69
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 248 2e-64
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 247 4e-64
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 239 1e-61
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 235 1e-60
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 231 1e-59
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 229 8e-59
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 229 1e-58
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 228 1e-58
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 227 2e-58
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 227 2e-58
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 227 3e-58
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 224 2e-57
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 219 1e-55
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 218 1e-55
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 216 6e-55
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 215 2e-54
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 213 4e-54
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 213 6e-54
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 212 1e-53
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 212 1e-53
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 210 3e-53
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 205 1e-51
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 204 3e-51
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 202 1e-50
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 201 2e-50
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 201 2e-50
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 201 2e-50
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 200 4e-50
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 199 7e-50
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 199 1e-49
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 198 2e-49
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 196 7e-49
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 194 3e-48
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 192 8e-48
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 192 1e-47
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 190 3e-47
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 190 6e-47
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 190 6e-47
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 189 8e-47
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 188 1e-46
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 188 1e-46
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 188 1e-46
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 188 1e-46
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 188 2e-46
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 187 4e-46
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 187 4e-46
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 186 6e-46
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 184 3e-45
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 183 7e-45
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 181 2e-44
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 181 3e-44
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 180 5e-44
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 180 6e-44
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 178 1e-43
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 178 2e-43
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 178 2e-43
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 176 6e-43
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 176 8e-43
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 176 8e-43
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 176 8e-43
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 176 8e-43
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 175 1e-42
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 175 1e-42
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 175 1e-42
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 175 2e-42
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 175 2e-42
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 175 2e-42
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 174 3e-42
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 173 6e-42
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 173 6e-42
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 173 7e-42
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 172 1e-41
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 172 1e-41
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 171 2e-41
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 171 3e-41
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 169 1e-40
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 169 1e-40
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 168 2e-40
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 168 2e-40
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 167 3e-40
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 167 5e-40
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 167 5e-40
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 166 8e-40
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 166 8e-40
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 165 1e-39
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 165 2e-39
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 165 2e-39
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 165 2e-39
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 163 4e-39
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 163 4e-39
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 163 8e-39
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 162 1e-38
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 162 1e-38
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 162 1e-38
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 162 1e-38
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 161 2e-38
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 160 4e-38
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 160 4e-38
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 159 7e-38
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 159 1e-37
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 159 1e-37
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 159 1e-37
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 158 2e-37
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 158 2e-37
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 158 2e-37
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 157 5e-37
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 156 9e-37
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 156 9e-37
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 156 9e-37
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 155 2e-36
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 155 2e-36
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 154 3e-36
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 154 4e-36
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 154 4e-36
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 153 6e-36
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 153 6e-36
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 153 8e-36
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 153 8e-36
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 152 1e-35
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 152 1e-35
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 152 1e-35
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 151 2e-35
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 151 2e-35
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 151 3e-35
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 150 6e-35
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 150 6e-35
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 150 6e-35
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 150 6e-35
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 149 1e-34
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 149 1e-34
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 149 1e-34
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 148 2e-34
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 148 2e-34
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 148 2e-34
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 147 3e-34
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 147 3e-34
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 147 4e-34
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 147 4e-34
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 146 5e-34
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 146 7e-34
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 146 7e-34
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 146 7e-34
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 146 1e-33
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 145 1e-33
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 145 2e-33
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 144 2e-33
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 144 3e-33
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 144 4e-33
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 143 5e-33
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 143 5e-33
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 143 5e-33
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 143 5e-33
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 143 7e-33
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 143 7e-33
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 143 7e-33
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 143 7e-33
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 143 7e-33
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 142 9e-33
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 142 9e-33
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 142 1e-32
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 142 1e-32
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 142 1e-32
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 142 2e-32
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 141 2e-32
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 141 2e-32
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 141 3e-32
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 141 3e-32
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 140 4e-32
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 140 4e-32
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 140 5e-32
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 140 5e-32
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 139 8e-32
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 139 1e-31
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 138 1e-31
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 138 1e-31
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 138 1e-31
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 138 2e-31
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 138 3e-31
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 138 3e-31
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 136 6e-31
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 136 8e-31
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 135 1e-30
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 135 1e-30
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 135 1e-30
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 135 2e-30
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 135 2e-30
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 134 2e-30
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 134 3e-30
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 133 5e-30
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 133 5e-30
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 133 5e-30
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 133 7e-30
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 132 1e-29
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 132 1e-29
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 132 1e-29
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 132 2e-29
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 132 2e-29
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 131 3e-29
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 131 3e-29
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 130 4e-29
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 130 4e-29
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 130 5e-29
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 130 5e-29
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 130 7e-29
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 129 9e-29
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 129 9e-29
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 129 1e-28
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 128 2e-28
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 128 2e-28
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 128 3e-28
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 127 4e-28
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 127 5e-28
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 127 5e-28
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 126 8e-28
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 125 2e-27
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 124 3e-27
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 124 3e-27
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 123 6e-27
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 123 6e-27
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 123 6e-27
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 123 8e-27
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 123 8e-27
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 123 8e-27
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 122 2e-26
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 121 3e-26
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 121 3e-26
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 121 3e-26
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 120 5e-26
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 120 7e-26
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 119 1e-25
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 119 1e-25
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 118 2e-25
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 118 3e-25
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 118 3e-25
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 117 5e-25
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 116 9e-25
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 116 9e-25
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 116 1e-24
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 115 2e-24
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 115 2e-24
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 113 8e-24
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 113 8e-24
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 112 1e-23
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 112 1e-23
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 111 2e-23
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 111 3e-23
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 110 4e-23
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 110 4e-23
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 110 4e-23
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 110 6e-23
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 109 8e-23
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 109 1e-22
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 108 2e-22
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 107 4e-22
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 106 9e-22
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 106 9e-22
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 105 2e-21
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 104 3e-21
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 103 5e-21
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 103 5e-21
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 102 1e-20
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 101 2e-20
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 101 2e-20
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 100 5e-20
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 100 1e-19
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 100 1e-19
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 100 1e-19
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 98 3e-19
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 98 3e-19
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 98 3e-19
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 97 8e-19
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 96 1e-18
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 96 1e-18
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 96 1e-18
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 95 2e-18
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 95 2e-18
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 95 3e-18
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 95 3e-18
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 94 5e-18
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 93 7e-18
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 93 7e-18
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 93 7e-18
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 93 9e-18
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 93 1e-17
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 93 1e-17
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 93 1e-17
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 91 3e-17
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 91 3e-17
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 91 3e-17
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 91 3e-17
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 91 5e-17
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 91 5e-17
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 90 7e-17
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 90 9e-17
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 89 2e-16
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 88 3e-16
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 88 4e-16
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 87 6e-16
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 87 8e-16
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 87 8e-16
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 86 1e-15
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 83 1e-14
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 82 2e-14
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 81 3e-14
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 81 4e-14
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 81 5e-14
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 81 5e-14
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 80 7e-14
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 80 9e-14
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 79 1e-13
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 79 2e-13
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 79 2e-13
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 79 2e-13
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 79 2e-13
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 79 2e-13
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 78 4e-13
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 78 4e-13
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 78 4e-13
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 77 5e-13
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 77 7e-13
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 77 7e-13
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 77 9e-13
UniRef50_A5V463 Cluster: Aldo/keto reductase; n=1; Sphingomonas ... 76 1e-12
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 76 1e-12
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 76 1e-12
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 75 2e-12
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 75 3e-12
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 74 5e-12
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 73 8e-12
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 72 2e-11
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 72 2e-11
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 71 3e-11
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 71 3e-11
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 71 4e-11
UniRef50_A2UBY5 Cluster: Plant-metabolite dehydrogenase; n=1; Ba... 71 4e-11
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 71 4e-11
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 70 8e-11
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 70 1e-10
UniRef50_A6BFM9 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 68 4e-10
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 68 4e-10
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 68 4e-10
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 67 5e-10
UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 66 9e-10
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 66 1e-09
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 66 1e-09
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 66 1e-09
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 66 2e-09
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 66 2e-09
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 65 2e-09
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 65 3e-09
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 63 9e-09
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 63 1e-08
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 63 1e-08
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 62 2e-08
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 62 2e-08
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 62 3e-08
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 62 3e-08
UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 62 3e-08
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 61 4e-08
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 61 4e-08
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 61 5e-08
UniRef50_Q09923 Cluster: Aldo-keto reductase yakc [NADP+]; n=13;... 61 5e-08
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 60 6e-08
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 60 6e-08
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 60 1e-07
UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 59 2e-07
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 59 2e-07
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 58 3e-07
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 58 3e-07
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 58 4e-07
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 58 4e-07
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 58 4e-07
UniRef50_A3DM42 Cluster: Aldo/keto reductase; n=1; Staphylotherm... 58 4e-07
UniRef50_Q5ZRR0 Cluster: Aldo/keto reductase; n=3; Legionella pn... 57 8e-07
UniRef50_A4XIJ0 Cluster: Aldo/keto reductase; n=1; Caldicellulos... 57 8e-07
UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 56 1e-06
UniRef50_Q1IPE6 Cluster: Aldo/keto reductase; n=21; Bacteria|Rep... 56 1e-06
UniRef50_Q14LU7 Cluster: Putative aldo/keto reductase n-terminal... 56 1e-06
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 56 1e-06
UniRef50_Q31DD1 Cluster: Aldo/keto reductase family; n=5; Prochl... 56 2e-06
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 56 2e-06
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 55 2e-06
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 55 2e-06
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 55 3e-06
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 55 3e-06
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06
UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 55 3e-06
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 54 4e-06
UniRef50_Q84M96 Cluster: At1g60680; n=19; cellular organisms|Rep... 54 4e-06
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 54 4e-06
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 54 5e-06
UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif... 54 5e-06
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 53 9e-06
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 53 9e-06
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 53 9e-06
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 53 9e-06
UniRef50_Q8ZYV2 Cluster: Oxidoreductase, conjectural; n=3; Pyrob... 53 9e-06
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 53 9e-06
UniRef50_Q9W2X0 Cluster: CG32688-PA, isoform A; n=4; Sophophora|... 53 1e-05
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 53 1e-05
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 52 2e-05
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 52 2e-05
UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 52 2e-05
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 52 2e-05
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 52 2e-05
UniRef50_A5FZX7 Cluster: Aldo/keto reductase precursor; n=4; Bac... 52 2e-05
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 52 3e-05
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 52 3e-05
UniRef50_Q0CV71 Cluster: Putative uncharacterized protein; n=2; ... 52 3e-05
UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 51 4e-05
UniRef50_A4AP98 Cluster: Putative uncharacterized protein; n=1; ... 51 4e-05
UniRef50_A3I2P1 Cluster: Putative oxidoreductase-possibly Aldo/k... 51 4e-05
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 51 4e-05
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 51 4e-05
UniRef50_UPI0000DB6B5C Cluster: PREDICTED: similar to glutamate-... 51 5e-05
UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 51 5e-05
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 51 5e-05
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 51 5e-05
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 51 5e-05
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 51 5e-05
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 51 5e-05
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 50 7e-05
UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b... 50 7e-05
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05
UniRef50_Q1FEK2 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 50 9e-05
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 9e-05
UniRef50_Q4WE75 Cluster: Aldehyde reductase (GliO), putative; n=... 50 9e-05
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 50 1e-04
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 50 1e-04
UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3... 50 1e-04
UniRef50_Q338B1 Cluster: Auxin-induced protein PCNT115, putative... 50 1e-04
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 49 2e-04
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 49 2e-04
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 49 2e-04
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 49 2e-04
UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket... 49 2e-04
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 49 2e-04
UniRef50_A7GIW7 Cluster: Oxidoreductase, aldo/keto reductase fam... 49 2e-04
UniRef50_A6XQ31 Cluster: Putative uncharacterized protein; n=1; ... 49 2e-04
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 3e-04
UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol... 48 3e-04
UniRef50_A7DBQ3 Cluster: Aldo/keto reductase precursor; n=2; Met... 48 3e-04
UniRef50_A4A767 Cluster: Aldo/keto reductase/Endoribonuclease L-... 48 3e-04
UniRef50_A7Q5Z6 Cluster: Chromosome chr14 scaffold_54, whole gen... 48 3e-04
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 48 3e-04
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 48 3e-04
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04
UniRef50_A0GAJ5 Cluster: Aldo/keto reductase precursor; n=9; Pro... 48 4e-04
UniRef50_Q14722 Cluster: Voltage-gated potassium channel subunit... 48 4e-04
UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 48 5e-04
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 48 5e-04
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 47 6e-04
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 47 6e-04
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 47 6e-04
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 47 6e-04
UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos... 47 6e-04
UniRef50_Q8R6G2 Cluster: Oxidoreductase; n=1; Fusobacterium nucl... 47 8e-04
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 47 8e-04
UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi... 46 0.001
UniRef50_A1VNV6 Cluster: Aldo/keto reductase precursor; n=7; Pro... 46 0.001
UniRef50_A1SY15 Cluster: Aldo/keto reductase; n=1; Psychromonas ... 46 0.001
UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 46 0.001
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 46 0.001
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 46 0.001
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 46 0.001
UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 46 0.001
UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 0.002
UniRef50_A3K469 Cluster: Aldo/keto reductase; n=3; Rhodobacterac... 46 0.002
UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium ad... 46 0.002
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 46 0.002
UniRef50_O43448 Cluster: Voltage-gated potassium channel subunit... 46 0.002
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 45 0.002
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 45 0.002
UniRef50_Q74DE6 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.002
UniRef50_Q8VV02 Cluster: Putative oxidoreductase; n=1; Streptomy... 45 0.002
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 45 0.002
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 45 0.002
UniRef50_A6C2P2 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.002
UniRef50_A5EX65 Cluster: Aldo/keto reductase family protein; n=1... 45 0.002
UniRef50_Q3AD20 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.003
UniRef50_P73573 Cluster: Sll0867 protein; n=15; Bacteria|Rep: Sl... 45 0.003
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 45 0.003
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 45 0.003
UniRef50_Q75DD3 Cluster: ABR094Wp; n=1; Eremothecium gossypii|Re... 45 0.003
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 44 0.004
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 44 0.004
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 44 0.004
UniRef50_A4MAE7 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 44 0.004
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 44 0.004
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 279 bits (684), Expect = 7e-74
Identities = 138/317 (43%), Positives = 200/317 (63%), Gaps = 5/317 (1%)
Query: 25 SAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 84
SA + VP L++ + +P +ALGT+LG G V V+ A++ GY H DTA
Sbjct: 17 SATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAA 76
Query: 85 KYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 143
Y E +VG A+ K EG +KRE +F+TTKLWN++H+REQV A++++L L+YVDL
Sbjct: 77 IYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDL 136
Query: 144 YLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK 203
+L+HWPIA+ E D N D+L+TWR + KLG TKSIG+SNFN+ Q+ ++ K
Sbjct: 137 FLMHWPIALNE-DYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQECTIK 195
Query: 204 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIA 263
P ALQIE++ + Q +L + ++ I+VM Y+PFGSL + D P P++DD L S+A
Sbjct: 196 PVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPFGSLV-KRFGMDLPGPKMDDPVLTSLA 254
Query: 264 QKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR- 322
+KY KT Q+ LR+L++ V +PK+V +R+ +NI +FDF L EE + F++ R
Sbjct: 255 KKYEKTPAQIVLRWLVDRKVVPIPKTVSPKRLLENINIFDFKLKEEEIEKINQFNSNTRY 314
Query: 323 TLPQTKWSKHPDYPFQL 339
TLP W KHP YPF +
Sbjct: 315 TLPSF-WQKHPFYPFDM 330
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 264 bits (648), Expect = 2e-69
Identities = 132/322 (40%), Positives = 198/322 (61%), Gaps = 19/322 (5%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
V + LS G +PV+ LGTW G +V E AV A++AGY H D A YG E
Sbjct: 5 VDEITLSDGNKVPVLGLGTWQGGNDPDEV-------ENAVKLAIDAGYRHFDCASFYGNE 57
Query: 90 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
++G+A+ +K +G+ KRE +F+ TK+WN ++E V+ A ++SL+ L L Y+DLYL+HW
Sbjct: 58 AEIGKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHW 117
Query: 149 PIA---MFE-------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
P + +++ N LD VD+++TWRGM + KLGLT+SIG+SNFN +Q+ R+++
Sbjct: 118 PFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLE 177
Query: 199 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKA-QPDAPPPRIDDE 257
S KP QIEL++NL Q +L +FC I V Y+PFG+ + QP +
Sbjct: 178 SASIKPVMNQIELHINLNQKKLREFCASKSIAVTGYSPFGAPGRNNVFQPAGADISLQSP 237
Query: 258 RLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSF 317
+ IA+KYNKT Q+ LR++I++GA+ +PKS ++RI++NI +FDF LTPEE +
Sbjct: 238 VITGIAKKYNKTNAQIVLRYVIDIGAIPIPKSSSEKRIKENIDIFDFKLTPEEIAAIDKL 297
Query: 318 DTGYRTLPQTKWSKHPDYPFQL 339
D G+RT + +YPF +
Sbjct: 298 DCGFRTCSAIEHKDCKEYPFNI 319
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 248 bits (606), Expect = 2e-64
Identities = 134/290 (46%), Positives = 183/290 (63%), Gaps = 15/290 (5%)
Query: 31 PTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
P QL+ G IP +ALGT+ G PK QAV++A++AGY HIDTA YG E
Sbjct: 25 PLKQLNDGNAIPSLALGTFGFGDIPK---------VRQAVLWAIQAGYRHIDTAALYGNE 75
Query: 90 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
++VG+ + +GL KRE +F+TTKLWN H R QV+PALR+SL L L YVDLYLIH
Sbjct: 76 EEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHS 135
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
P A EN +D +D L+TW GM +AKKLGL KSIG+SNF+ + R+I P+ Q
Sbjct: 136 PEATNENGDPVD-IDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVPAVNQ 194
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
IE++ + Q +L E I VMAY+PFG + S+ + P +D + IA+KYNK
Sbjct: 195 IEVHPSKTQEKLVADSHERGIEVMAYSPFG-FYVSRGSHNNPVK--NDRTVADIARKYNK 251
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
TV QV +R+L+E + +PKS +++RI +NI +FDF L+PE+ N + D
Sbjct: 252 TVNQVLVRYLLERSLIPIPKSTNQQRIRENIDVFDFQLSPEDINAIGKLD 301
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 247 bits (604), Expect = 4e-64
Identities = 124/297 (41%), Positives = 189/297 (63%), Gaps = 24/297 (8%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
VPT+ + G +P++ LGT+L +P G+V + AV YA+E GY H+DTA+ Y E
Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLS-KP-GEVAE-------AVKYAIEVGYRHVDTAFFYENE 53
Query: 90 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
++G A+ +K ++G +KRE IF+TTKLW + H+ ++V+PA +KSLENL +Y+DL+L+HW
Sbjct: 54 KEIGSAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHW 113
Query: 149 PIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
P A D L + D+L+TW+GM + K+ GL +SIG+SNFN EQI R++
Sbjct: 114 PFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLS 173
Query: 199 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
S KP Q+E+ +NL Q L +FC++++I V ++P G P D+ +
Sbjct: 174 SAKIKPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLGR--PGNRH--GIQNLWDEPQ 229
Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLK 315
+ +AQKY KT +A RF+ +LG +PKSV K RI++N+ +FDFSLTPEE + ++
Sbjct: 230 IQKLAQKYKKTPANIACRFIHQLGVTPIPKSVTKSRIKENLDIFDFSLTPEEVSTIE 286
Score = 234 bits (572), Expect = 3e-60
Identities = 116/271 (42%), Positives = 169/271 (62%), Gaps = 12/271 (4%)
Query: 77 YTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLEN 135
Y HIDTAY Y E +G A+ +K +G +KRE +F+TTKL H+ +V+PA ++SL +
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 136 LNLEYVDLYLIHWPIAMF-------ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNF 188
L L+Y+DLYLIHWPI + LL + D+L+TW+GM + K+ GL +SIG+SNF
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVSNF 420
Query: 189 NQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPD 248
N EQI R++++ KP Q+E++L L Q L +FC+++DI V Y+P G +
Sbjct: 421 NSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPLGRPGNRYGITN 480
Query: 249 APPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTP 308
A DD + + +KY KT Q+A RF+ +LGA+ +PKSV K RI++N ++FDFSLT
Sbjct: 481 A----WDDPIIQELVKKYGKTPAQIACRFVSQLGAIPIPKSVTKSRIKENFEIFDFSLTD 536
Query: 309 EEFNLLKSFDTGYRTLPQTKWSKHPDYPFQL 339
EE N ++S TG R P + YPF +
Sbjct: 537 EEINSIQSIATGERVAPMEDAKESKYYPFNI 567
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 239 bits (584), Expect = 1e-61
Identities = 128/317 (40%), Positives = 194/317 (61%), Gaps = 21/317 (6%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
+ PT++L++G +P + LGTW +D + +AL+ GY H+DTA+ Y
Sbjct: 4 LAPTIRLNNGREMPTLGLGTWKSFE---------SDAYHSTRHALDVGYRHLDTAFVYEN 54
Query: 89 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E +VG+A+++K +EG+ RE +F+TTKL +H+ V A R SL NL LEYVDLYL+H
Sbjct: 55 EAEVGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMH 114
Query: 148 WPIAM-FEND-----TL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 200
P+ F ND TL L +VD+LDTWR M LGLT+SIG+SNFN Q +R++ +
Sbjct: 115 MPVGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANC 174
Query: 201 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLV 260
+P Q+E + QQ +L + + + +V+ AY P P++ P P + DE
Sbjct: 175 RIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPLARPQPARQWP----PFLYDEHAQ 230
Query: 261 SIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
++A+KY +T Q+ LR+L++LG V LPKS +K RIE+N ++FDF L+P++ ++ + TG
Sbjct: 231 NLAKKYGRTTAQICLRYLVQLGVVPLPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTG 290
Query: 321 YRTLPQTKWSKHPDYPF 337
RT+P + S H YPF
Sbjct: 291 QRTVPFSGMSGHKYYPF 307
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 235 bits (575), Expect = 1e-60
Identities = 131/327 (40%), Positives = 197/327 (60%), Gaps = 27/327 (8%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+PT++L++G +P + LGT + KG ++ +AV+ A++ G+ HIDTAY Y E
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMS---KG------DECCKAVMTAIDEGFRHIDTAYNYRNE 56
Query: 90 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
D VGRA+ K EG+ RE +F+TTKLWN++H + V A KSLE+L L+YVDL+LIH
Sbjct: 57 DVVGRAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHM 116
Query: 149 PIAMF------ENDTLLD---NV-----DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 194
P E T LD NV D++DTW+ M + G SIG+SNFN EQ++
Sbjct: 117 PFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLE 176
Query: 195 RIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG--SLFPSKAQPDAPPP 252
RI+ + KP Q+E + + Q L +FC E DIVV A++PFG LF K D P P
Sbjct: 177 RILANCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSPFGRPHLF-EKNPKDKPKP 235
Query: 253 RIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFN 312
+D+ +V I +K++K+ QV LR+L++ G V +PKS + ++QN+++FDF L+ ++
Sbjct: 236 VLDEPEIVEIGKKFDKSSAQVVLRYLLQNGVVPIPKSTSAQHLKQNLEIFDFELSSDDMA 295
Query: 313 LLKSFDTGYRTLPQTKWSKHPDYPFQL 339
+L F+T R + + +H YPF +
Sbjct: 296 ILDGFNTNQRMVRLSLLKEHKYYPFNI 322
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 231 bits (566), Expect = 1e-59
Identities = 122/323 (37%), Positives = 184/323 (56%), Gaps = 24/323 (7%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
+VP +G +IP+ LGTW + P G+V Q D A++ GY HID A+ Y
Sbjct: 5 VVPNAIFKNGNSIPMFGLGTW--NSPPGQVAQAVKD-------AIDVGYRHIDCAHVYQN 55
Query: 89 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E +VG + K +EG+ KRE +F+T+KLWN++H + V A + +L+NL L+Y+DLYLIH
Sbjct: 56 EHEVGEGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIH 115
Query: 148 WPIAMFENDTLL-----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 196
WP+ E L + D++DTW M GL ++IG+SNFN +Q+QR+
Sbjct: 116 WPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRV 175
Query: 197 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPP-RID 255
+D P+ QIE + L Q ++ FC E I+V AY+P GS P++ A P +D
Sbjct: 176 LDVARIPPATNQIECHPYLHQSKITTFCAEKGIIVTAYSPLGS--PARPWVKADDPVLMD 233
Query: 256 DERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLK 315
D + +A+K+ K+ Q+ +R+ I+LG VV+PKSV KERI N +F F L ++ L
Sbjct: 234 DATVGQLAKKHGKSAAQILIRYQIQLGHVVIPKSVTKERIASNFDVFSFQLDEDDMKQLA 293
Query: 316 SFDTGYRTLPQTKWSKHPDYPFQ 338
+ R P++ HP +PF+
Sbjct: 294 GLERNGRICPESSAFGHPHHPFE 316
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 229 bits (560), Expect = 8e-59
Identities = 121/319 (37%), Positives = 188/319 (58%), Gaps = 21/319 (6%)
Query: 33 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
++L+ G +PV+ GT+ + PK E+ A++ GY HID A+ YG E++
Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLA-------EEGTKVAIDVGYRHIDCAFLYGNEEE 61
Query: 92 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VGRA+ K ++G +KRE +F T KLW++ H E+V PAL KSL++L L+Y+DL++IH P+
Sbjct: 62 VGRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPM 121
Query: 151 AMFENDTLLD----------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
D L N D DTW+ + K GL +SIG+SNFN +Q++ I++
Sbjct: 122 EFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMP 181
Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
GL+ KP Q+E ++ L Q +L +FC+ DIV++ Y+ GS + + P ++D
Sbjct: 182 GLKYKPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDPA 241
Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
L IA+K+N+T QVA+R+ ++ G VVL KS RI+QN Q+FDF L E+ + +
Sbjct: 242 LTEIAKKHNRTPAQVAMRYHLQRGVVVLAKSFTPARIQQNFQVFDFQLDAEDMRSIDGLN 301
Query: 319 TGYRTLPQTKWSKHPDYPF 337
R + ++WS HP YP+
Sbjct: 302 RNMRYIDTSRWSDHPKYPY 320
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 229 bits (559), Expect = 1e-58
Identities = 125/318 (39%), Positives = 186/318 (58%), Gaps = 19/318 (5%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
++L+ G IP + GT+ K K V + E A + AL+ GY H+DTAY Y +E+++
Sbjct: 8 VKLNDGHLIPALGFGTY-----KPKEVPKSKSLEAACL-ALDVGYRHVDTAYAYQVEEEI 61
Query: 93 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
G+A+ K G+ KRE +FITTKLW + E V PAL KSL+ L L+YVDLY++H+P+
Sbjct: 62 GQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVP 121
Query: 152 MFEND----------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
M D +LLD VDF DTW + + K GL KSIG+SNFN Q++RI++ G
Sbjct: 122 MKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPG 181
Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
L+ KP Q+E +L L Q +L +C DIV++AY G+ + P ++D L
Sbjct: 182 LKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVL 241
Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
+A+K ++ +ALR+LI+ G V L +S + + +N+Q+F F L+PE+ L +
Sbjct: 242 CDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNK 301
Query: 320 GYRTLPQTKWSKHPDYPF 337
+R LP HP+YPF
Sbjct: 302 NFRYLPAEFLVDHPEYPF 319
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 228 bits (558), Expect = 1e-58
Identities = 128/334 (38%), Positives = 192/334 (57%), Gaps = 28/334 (8%)
Query: 32 TLQLSSGGNIPVVALGTWL------------GH---RPKGKVVQVTNDTEQAVIYALEAG 76
++QL G +PVVA GT+ GH G +D A AL+ G
Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMALDLG 67
Query: 77 YTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLEN 135
Y H+D A+ Y E VG+A +KF++G LKRE +F T+KLWN++H+ V PAL K+L
Sbjct: 68 YRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSF 127
Query: 136 LNLEYVDLYLIHWPIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGI 185
L ++YVDLYLIH P++ + L D D L TW+ + + + GL KSIG+
Sbjct: 128 LQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKSIGV 187
Query: 186 SNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPS 243
SNFN+ Q++ I++ GL+ KP QIE + L Q ++ +FC+ DIVV+AY GS
Sbjct: 188 SNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAYGVLGSPGAG 247
Query: 244 KAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFD 303
K + P ++D L+SI QKY+K+ QV++R++I+ G V + KS + +R++QN+++FD
Sbjct: 248 KWVDQSCPILLEDPVLISIGQKYSKSPAQVSMRYMIQRGCVAIAKSFNPDRMKQNLEVFD 307
Query: 304 FSLTPEEFNLLKSFDTGYRTLPQTKWSKHPDYPF 337
F L+ EE + + R ++W KHP YPF
Sbjct: 308 FQLSQEEMAAIDGLNKNMRYWSFSEWEKHPQYPF 341
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 227 bits (556), Expect = 2e-58
Identities = 128/318 (40%), Positives = 188/318 (59%), Gaps = 23/318 (7%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
L+L++G +P + LGTW P G+V + AV A++ GY HID A Y E +V
Sbjct: 5 LELNNGTKMPTLGLGTWKS--PPGQVTE-------AVKVAIDLGYRHIDCAQVYQNEKEV 55
Query: 93 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
G AL +K E + KR+ +FI +KLW ++H++ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTG 115
Query: 152 M----------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
+ + + DF+DTW M GL K+IG+SNFN QI+RI++ G
Sbjct: 116 FKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPG 175
Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
L+ KP+ QIE + L Q +L ++C IVV AY+P GS A+P+ P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234
Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
+IA KYNKT QV +RF I+ VV+PKSV RI +N+++FDF ++ E+ L S++
Sbjct: 235 KAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNR 294
Query: 320 GYRTLPQTKWSKHPDYPF 337
+R +KH DYPF
Sbjct: 295 NWRVCALMSCAKHKDYPF 312
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 227 bits (556), Expect = 2e-58
Identities = 119/321 (37%), Positives = 188/321 (58%), Gaps = 19/321 (5%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+ ++L+ G +IPV+ GT+ + + ++ A++ G+ HID ++ Y E
Sbjct: 5 IQKIELNDGHSIPVLGFGTYATEE------HLKKKSMESTKIAIDVGFCHIDCSHLYQNE 58
Query: 90 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
+++G+A+ K +G +KRE IF T+KLW++ H E V P+L SL LNL+YVDLYLIH+
Sbjct: 59 EEIGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHF 118
Query: 149 PIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
P+++ + LL D VD DTW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 119 PVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 199 S-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDD 256
GL+ KP Q+E +L L Q +L +C+ NDIV++AY G+ + P +DD
Sbjct: 179 KPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDD 238
Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
L ++A+KY +T +ALR+ ++ G V L KS ++ERI +N+Q+FDF L ++ +L
Sbjct: 239 PVLCAMAKKYKRTPALIALRYQLDRGIVALAKSFNEERIRENMQVFDFQLASDDMKILDG 298
Query: 317 FDTGYRTLPQTKWSKHPDYPF 337
D R P + HP++PF
Sbjct: 299 LDRNLRYFPADMFKAHPNFPF 319
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 227 bits (555), Expect = 3e-58
Identities = 127/318 (39%), Positives = 187/318 (58%), Gaps = 18/318 (5%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 93 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 152 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184
Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
L+ KP + Q+E + QP+L KFC+++DIV+ AY+P G+ + PP + D L
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244
Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
S+ ++YNKT Q+ LRF I+ G VV+PKS + ERI++N Q+FDFSLT EE +++ +
Sbjct: 245 NSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNK 304
Query: 320 GYRTLPQTKWSKHPDYPF 337
R + W HP+YPF
Sbjct: 305 NVRFVELLMWRDHPEYPF 322
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 224 bits (548), Expect = 2e-57
Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 93 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P+ P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234
Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
+IA K+NKT QV +RF ++ VV+PKSV ERI +N ++FDF L+ ++ L S++
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294
Query: 320 GYRTLPQTKWSKHPDYPF 337
+R + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 219 bits (534), Expect = 1e-55
Identities = 124/321 (38%), Positives = 183/321 (57%), Gaps = 23/321 (7%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P+ LSSG N+P+V LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PSFLLSSGRNMPMVGLGTW---RSPPEVVA------QAVKDAIDIGYRHFDCAHIYGNEL 54
Query: 91 QVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
VG A+ +K EGL R+ +FIT+KLWN++H+ E V A SL NL ++Y+DLYL+HWP
Sbjct: 55 HVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWP 114
Query: 150 IAMFENDTL-----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
+A D L +++D+LDTW+ M D GL +IG+SNFN++QI R++
Sbjct: 115 MAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLC 174
Query: 199 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
KP LQIE + L+Q L C +N I V AY+ GS +P + P + +
Sbjct: 175 LAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYSSLGSGHTPYEKPGS-YPLLQNPI 233
Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNI-QLFDFSLTPEEFNLLKSF 317
+VS+A+KY +T QV LR+ + G +V+P+SV K+ + N +++DF L ++ +
Sbjct: 234 IVSVAEKYGRTPAQVLLRYQTQSGIIVIPRSVSKQHMHDNFKRIWDFQLAIDDVKAIDGL 293
Query: 318 DTGYRTLPQTKWSKHPDYPFQ 338
D R + HP +PF+
Sbjct: 294 DCNGRFMTMKAAYGHPHHPFE 314
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 218 bits (533), Expect = 1e-55
Identities = 124/326 (38%), Positives = 189/326 (57%), Gaps = 29/326 (8%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
VPT++ S+G IPV+ GT+L KG+ V++ A++ GY HIDTA+ Y E
Sbjct: 5 VPTVRFSNGYEIPVLGYGTYLAQ--KGQCVELVKK-------AIDLGYRHIDTAFLYENE 55
Query: 90 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
++G+A+ K +EG ++RE +F+TTKLWN++H+ + V A R+S + L++ Y+DL+L+H
Sbjct: 56 VEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHS 115
Query: 149 PIAM----FE----------NDTLLDNVDFLDTWRGMIDAKKL-GLTKSIGISNFNQEQI 193
P+ + +E + L +VD+++TW+ M G +SIG+SNFN EQI
Sbjct: 116 PMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQI 175
Query: 194 QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPR 253
+RI+ KP Q+E N Q +L FC+ I V AY P G P + +
Sbjct: 176 ERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGPMGR--PHRT-TNGNRNA 232
Query: 254 IDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNL 313
+DD +++ I +KY KT QV LR+LI++G + +P S ++ER+ QNI + DF LT EE
Sbjct: 233 LDDPKVLEIGRKYGKTGGQVILRYLIDIGTIPIPYSTNEERMRQNIDVCDFKLTGEEIEY 292
Query: 314 LKSFDTGYRTLPQTKWSKHPDYPFQL 339
L SF + RT+P H YPF L
Sbjct: 293 LASFHSA-RTIPFLPLKSHKYYPFDL 317
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 216 bits (528), Expect = 6e-55
Identities = 123/316 (38%), Positives = 180/316 (56%), Gaps = 23/316 (7%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L +G +P+V LGTW P KV +AV A++AGY HID AY Y E +VG
Sbjct: 7 LLTGAKMPIVGLGTWKS--PPAKV-------REAVKVAIDAGYRHIDCAYVYQNESEVGE 57
Query: 95 ALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 153
A+ +K E +KRE +FI +KLW+++ E+ V A + +L +L L+Y+DLYLIHWP
Sbjct: 58 AIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQ 117
Query: 154 ENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE 202
+ L D FLD W M + GL K++G+SNFN QI+R+++ GL+
Sbjct: 118 SGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLK 177
Query: 203 -KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS 261
KP Q+E + L Q +L ++C I + AY+P GS A+P+ P ++ ++
Sbjct: 178 HKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSPLGSPDRPSAKPE-DPLLLEIPKIKE 236
Query: 262 IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321
IA K+ KT QV +RF IE VV+PKSV RI++NIQ+FDF L+ E+ + SF+ +
Sbjct: 237 IAAKHKKTAAQVLIRFHIERNVVVIPKSVTPSRIQENIQVFDFQLSEEDMAAILSFNRNW 296
Query: 322 RTLPQTKWSKHPDYPF 337
R S + D+PF
Sbjct: 297 RACGLFAASHNEDFPF 312
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 215 bits (524), Expect = 2e-54
Identities = 123/312 (39%), Positives = 177/312 (56%), Gaps = 27/312 (8%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
++ L SG +P+V LGTW K K +V A+ A++AGY H D A YG E +
Sbjct: 4 SVTLPSGHAMPLVGLGTW-----KLKADEVAG----AIGAAVDAGYRHFDCALIYGNEKE 54
Query: 92 VGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VG AL + GLKRE +FITTK+WN++H +E V +SL +L L+Y+DLY++HWP+
Sbjct: 55 VGVALREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPL 114
Query: 151 AMFEN-------------DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 197
F+N D + +V +L+TW M D K G KS+G+SNFN +Q+ ++
Sbjct: 115 G-FQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVL 173
Query: 198 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRI-DD 256
PS LQ+E + L Q EL FCRE +VV AY+P G +A + P I DD
Sbjct: 174 QHSTVPPSVLQVESHPFLPQVELLNFCRERSVVVSAYSPLGC--GDRAWKLSGEPSIFDD 231
Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
L+ IAQ+ K++ QVA+RF ++ G V+PKS I++NI +FDF L+ ++ LL S
Sbjct: 232 PGLLKIAQRLRKSIAQVAIRFQVQRGIPVIPKSATPSHIQENINVFDFELSEDDMALLSS 291
Query: 317 FDTGYRTLPQTK 328
+P K
Sbjct: 292 LPRRRILVPPKK 303
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 213 bits (521), Expect = 4e-54
Identities = 126/326 (38%), Positives = 185/326 (56%), Gaps = 22/326 (6%)
Query: 30 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
+PT+ L+SG +IPV+ LGT LG K VT E A LE GY H D+A YG
Sbjct: 11 IPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETA----LECGYRHFDSAAYYGN 66
Query: 89 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E +G+ L + SEG +KRE +FITTKL + + V L+KSL+NL L YVDLYL+H
Sbjct: 67 EAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVH 126
Query: 148 WPIAMFEND---------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
+P + + D T+ D WR M G TK+IG+SNFN +Q+QRII
Sbjct: 127 YPCGILDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIK 186
Query: 199 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS---LFPSKAQPDAPPPRID 255
+P+ LQ+E+++ +QQ L FC ++DIVV A+ P G L ++P ++
Sbjct: 187 GCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGPFRLIRKASRPGEVKLLLE 246
Query: 256 DERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLK 315
D +++ +A ++KT QV LR+L ++ + +PKS + R+ QN Q+FDF LT E + L
Sbjct: 247 DPQVLDVATAHHKTPAQVLLRYLHQINVIPIPKSANPTRLFQNTQIFDFELTSAEMSRLA 306
Query: 316 SFDTGYRTLPQTKWSK----HPDYPF 337
D G+ T++ + HP++PF
Sbjct: 307 GLDRGHEGRIFTEFRRGDHTHPEFPF 332
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 213 bits (520), Expect = 6e-54
Identities = 119/322 (36%), Positives = 182/322 (56%), Gaps = 24/322 (7%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P LS+G N+P++ LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PNFLLSNGKNMPMLGLGTW---RSPPEVVT------QAVKDAIDIGYRHFDCAHIYGNEA 54
Query: 91 QVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
QVG AL +K EG+ R+ +FIT+KLWN++H+ + V PA S+ NL ++Y++LYL+HWP
Sbjct: 55 QVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWP 114
Query: 150 IAMFE------------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 197
+A N +++D++DTWR M + GL ++IG+SNFN++Q+ R++
Sbjct: 115 MAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLL 174
Query: 198 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDE 257
KP LQIE + L Q L C +N I V AY+ GS +P A P +
Sbjct: 175 SVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGA-YPLLQHP 233
Query: 258 RLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNI-QLFDFSLTPEEFNLLKS 316
+++IA+KY +T QV LRF + G +V+P+SV K+ + N +++DF L ++ +
Sbjct: 234 TILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINE 293
Query: 317 FDTGYRTLPQTKWSKHPDYPFQ 338
D R + HP +PF+
Sbjct: 294 LDCNGRFMTMKAAYGHPHHPFE 315
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 212 bits (518), Expect = 1e-53
Identities = 120/321 (37%), Positives = 183/321 (57%), Gaps = 21/321 (6%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
+V +L+L+SG +IP + LGTW +P G+V A+ A+ AGY HID A+ Y
Sbjct: 1 MVQSLKLNSGYSIPAIGLGTWQS-KP-GEVAA-------AIKTAVAAGYRHIDCAHVYQN 51
Query: 89 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
+ +VG AL + EG +KRE +FIT+K+WN++H + + L +L L YVDL LIH
Sbjct: 52 QKEVGEALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIH 111
Query: 148 WPIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 197
WP E L +VD+L+TW+ A+K G +SIG+SNF QIQR+
Sbjct: 112 WPQGYAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVW 171
Query: 198 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDE 257
D+ KP+ LQ+EL+ Q +L +FC+E IVV+ Y+P G+ + + D P + +E
Sbjct: 172 DAAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNE 231
Query: 258 RLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSF 317
+ IA+ + KT Q+ LR+ ++ G +PKSV +RI +N+ +FDF LT EE + +
Sbjct: 232 VVAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRISENLAVFDFQLTAEEISKIDGI 291
Query: 318 DTGYRTLP-QTKWSKHPDYPF 337
+ +R + + HP PF
Sbjct: 292 NKNWRIVDLSQRDGDHPHCPF 312
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 212 bits (518), Expect = 1e-53
Identities = 122/309 (39%), Positives = 176/309 (56%), Gaps = 31/309 (10%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPK-GKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
P+ +LSSG IP+V GTW GK V+V AL+AGY HID A Y E
Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEV----------ALDAGYRHIDCAAVYLNE 52
Query: 90 DQVGRALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
+VG A TKKF+ +KRE +FIT+KLWN++H++E V PAL ++L +L L+Y+DLYL+H
Sbjct: 53 KEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVH 112
Query: 148 WPIAM--FEND-----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 200
WP+A ND + + V +TW M GL KSIG+SNFN + + ++
Sbjct: 113 WPVAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYA 172
Query: 201 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLV 260
KP+A Q+EL+ L QPEL KFC +++I + AY+P G+ +D+E +
Sbjct: 173 RIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLGN-----------GAFVDNEEVG 221
Query: 261 SIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
+IA+KYNKT+P V ++ I+ V+PKS R+ +N LF+F + + L D
Sbjct: 222 AIAKKYNKTIPNVLCKWAIQKNFSVIPKSSTPSRVAENFDLFNFEIEEADMLFLDKMDKN 281
Query: 321 YRTLPQTKW 329
RT K+
Sbjct: 282 LRTCDPAKF 290
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 210 bits (514), Expect = 3e-53
Identities = 125/306 (40%), Positives = 177/306 (57%), Gaps = 24/306 (7%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
V L+LSSG IP V LGT +++ ++ + A+ ALE GY HIDTA+ Y E
Sbjct: 23 VEKLKLSSGHEIPAVGLGT--------STIKL-DEMDNAISSALENGYRHIDTAFSYDNE 73
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+G+ L K F +G KRE IFIT+KL + + + V L++SL++L L+YVD+YLIH P
Sbjct: 74 AAIGKILKKWFDKGGKREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTP 133
Query: 150 IAMFENDT-----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
A+ E + L D+VD W+ M K G KSIG+SNFNQ Q+ I +
Sbjct: 134 FAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYN 193
Query: 199 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS----LFPSKAQPDAPPPRI 254
+ KPS LQ+E + LQQ +L KFC+E++IV+ AY P GS L + P P +
Sbjct: 194 NAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAPLGSHNARLNLHRGTPKELPALV 253
Query: 255 DDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
+ + S+A KYNK+ Q+ LR I+ G V +PKS + +R + NI +FDF LT EE +
Sbjct: 254 ELPLIKSLAAKYNKSPGQILLRHTIQEGLVAIPKSSNAQRQKSNIDIFDFKLTDEEMKKI 313
Query: 315 KSFDTG 320
+ D G
Sbjct: 314 DALDKG 319
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 205 bits (500), Expect = 1e-51
Identities = 128/326 (39%), Positives = 186/326 (57%), Gaps = 29/326 (8%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T+ L +G +P++ GTW + E A+ ALEAGY HIDTA Y E
Sbjct: 5 TILLPNGELMPIIGFGTWQAQE---------KELEDALNIALEAGYRHIDTATSYENEKV 55
Query: 92 VGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
+G L F S+ LKR IFI TKL + E V ++ SL+NL LEY+DLYLIH PI
Sbjct: 56 IGDVLKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPI 115
Query: 151 AMFE-NDTL----------LDN-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
+ D L LDN + ++ W M K G TK+IG+SNFN QI+RI+
Sbjct: 116 GFEKVGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILK 175
Query: 199 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG--SLFPSKAQPDAPPPRIDD 256
+ K S LQIEL++ QQ EL KFC++ +I + AY+P G SL + + + +
Sbjct: 176 NTKMKISMLQIELHVYFQQKELVKFCKQENIPITAYSPLGSRSLIKLLNKTEEISDMLQN 235
Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
+ ++ IA+KY K+ Q+ LR++++ G VV+PKS++ +RI++NIQLFD+ + PE+ L +
Sbjct: 236 DVVMEIAKKYKKSSAQILLRYIVQNGIVVIPKSINPQRIKENIQLFDWEINPEDMKKLYN 295
Query: 317 FDTGYRT-LPQTKWSK----HPDYPF 337
D G + + K+ K HP+YPF
Sbjct: 296 LDRGESSRICDLKFFKGIETHPEYPF 321
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 204 bits (498), Expect = 3e-51
Identities = 111/300 (37%), Positives = 171/300 (57%), Gaps = 22/300 (7%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 95 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 153 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
+P+ LQ+E + L Q EL C+ + V AY+P GS + PD P +++ ++++
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237
Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
A+KY ++ Q+ LR+ ++ + +PKS+ RI QNI++FDF+ +PEE L + + +R
Sbjct: 238 AEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 202 bits (492), Expect = 1e-50
Identities = 121/315 (38%), Positives = 182/315 (57%), Gaps = 26/315 (8%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
L L++G +IP + LGT+ K+ +D A+ A+E GY IDTA+ Y E V
Sbjct: 2 LALNNGHSIPPIGLGTY-------KITG--SDGVAAIKSAVEFGYRLIDTAFVYNNEQVV 52
Query: 93 GRALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
G+AL + FS+G + RE +FI +KL ++H E V R SLE L L+YVDLYL+H P+
Sbjct: 53 GQALREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPV 112
Query: 151 AMFE----NDT--LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 204
A + ND + D V L+TW+ + + ++ GL +SIG+SNFN+EQ+ I+ G +P
Sbjct: 113 AARDSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRP 172
Query: 205 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQ 264
Q+E ++ Q +L KFC I++MAY+P G K +P +D L +A+
Sbjct: 173 VVNQVECSIGFHQVKLRKFCNREGILIMAYSPLG-----KPKPGKKHVFLDSSDLNKMAE 227
Query: 265 KYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR-- 322
KY ++ Q++LRFLIE+G + +PKS +R+++N+ + F L + L+SF R
Sbjct: 228 KYGRSPAQISLRFLIEIGTIPIPKSSKTDRMKENLDVLSFKLEETDVQALESFVKQQRSM 287
Query: 323 TLPQTKWSKHPDYPF 337
TL K SKH YPF
Sbjct: 288 TLDWLKSSKH--YPF 300
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 201 bits (491), Expect = 2e-50
Identities = 110/303 (36%), Positives = 175/303 (57%), Gaps = 21/303 (6%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
TL+ G +IP + LGTW D ++AV ALE GY HID A Y ED
Sbjct: 3 TLKFRDGDSIPSIGLGTWKSD---------PEDVKKAVKIALENGYKHIDCAAAYDNEDA 53
Query: 92 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VG A + F G +KRE IF+T+KLWN+ H++E VIPAL+K+L++LNL+Y+DLYL+HWP+
Sbjct: 54 VGEAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPV 113
Query: 151 AM---------FENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 200
A + D L L+ +T MI+AKK GL K +G+SNF++E+++ +
Sbjct: 114 AFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKV 173
Query: 201 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKA-QPDAPPPRIDDERL 259
E P Q+EL+ L Q +L+ +C + I++ Y+P GS S+ + D P +D+ +
Sbjct: 174 EEMPEMNQVELHPYLPQNDLYSYCSKEGILLTGYSPLGSGDRSEGMKADDEPSLFEDDTI 233
Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
+A++ N + Q + + + G V+PKS ++ RI++N++ + L+ E+ + +
Sbjct: 234 KKVAERNNISKGQTLIAWAKQRGTAVIPKSTNEGRIKENLESDNIELSKEDLEDIANIGK 293
Query: 320 GYR 322
YR
Sbjct: 294 NYR 296
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 201 bits (490), Expect = 2e-50
Identities = 129/328 (39%), Positives = 177/328 (53%), Gaps = 31/328 (9%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T++LSSG ++P++ LGTW P + E AV ALE+GY HIDTA+ YG E+
Sbjct: 27 TIKLSSGHDMPMIGLGTW--QMPPEAI-------EVAVTAALESGYRHIDTAFTYGNEEA 77
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
+G+ L K F +G KRE +FITTKL E V L+ SLE L LEYV++YLIH P A
Sbjct: 78 IGKTLKKWFDKGGKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFA 137
Query: 152 MF------------ENDTLLD-NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
+ +LD + D + WR M K G +SIG+SNFN+ Q+ + +
Sbjct: 138 FVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYE 197
Query: 199 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPS---KAQPDAPPPRID 255
KPS LQIEL QQ + + C E +I V A++ GS S K + P +
Sbjct: 198 HAEIKPSNLQIELQAYNQQRPMRELCAERNITVTAFSTLGSPGSSPDKKTRYIKSLPTLF 257
Query: 256 DERLV-SIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
D +V IA+ +N+T QV LR ++ G +VLPKS + RI+QNI +FDF+LT +E +
Sbjct: 258 DHPIVKKIAEAHNRTSAQVLLRHAVQNGIIVLPKSTNPGRIKQNIGIFDFALTEDEMQAM 317
Query: 315 KSFDTG-----YRTLPQTKWSKHPDYPF 337
D G + KHP YPF
Sbjct: 318 NGLDKGEKGRIFHFFIDKGVEKHPQYPF 345
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 201 bits (490), Expect = 2e-50
Identities = 125/296 (42%), Positives = 169/296 (57%), Gaps = 31/296 (10%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
VP++ L G +IP LGT+ P N+ V A+E GY HIDTA Y E
Sbjct: 9 VPSVLLGDGVSIPQFGLGTY--ELPP-------NEASSVVQSAIELGYRHIDTASLYANE 59
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+VGRA+ S G+KRE F+TTKLWNS + + A +SL+ L+L+YVDLYLIHWP
Sbjct: 60 REVGRAIA---SSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWP 114
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
E +++ W +++ K+ G KS+G+SNF E I +I ++G PS QI
Sbjct: 115 CPPSEL--------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQI 166
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
EL+ LQQ EL CR + I + ++ PF SK DA P L A++Y KT
Sbjct: 167 ELHPWLQQRELVLSCRNDGIQIESWGPFARF--SK-DLDAFP------ELTRPAKQYGKT 217
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP 325
QV LR+ I+ G VV PK+VH ER+ QNI +FDF LTP+E + + S D G+RT P
Sbjct: 218 PAQVILRWHIQKGYVVFPKTVHAERLRQNIDIFDFDLTPDEISGIDSLDAGFRTGP 273
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 200 bits (488), Expect = 4e-50
Identities = 104/256 (40%), Positives = 160/256 (62%), Gaps = 15/256 (5%)
Query: 64 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 122
DT++A+I A++ GY H DTA YG E +G AL + GL R+ +F+T+KLW + +
Sbjct: 37 DTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHP 96
Query: 123 EQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGMIDA 174
V+PALRKSL+ L LEY+DLYLIHWP++ E + LL D W M +
Sbjct: 97 HLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLP-FDVKGVWESMEEC 155
Query: 175 KKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAY 234
+KLGLTK+IG+SNF+ +++Q ++ +P Q+E+NL QQ +L +FC+EN I+V A+
Sbjct: 156 QKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAF 215
Query: 235 TPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKER 294
+P K P ++++ L IA+ + K++ QV+LR+L E G +PKS KER
Sbjct: 216 SPL-----RKGASRGPNEVMENDVLKEIAEAHGKSIAQVSLRWLYEQGVTFVPKSYDKER 270
Query: 295 IEQNIQLFDFSLTPEE 310
+ QN+ +FD++LT ++
Sbjct: 271 MNQNLHIFDWALTEQD 286
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 199 bits (486), Expect = 7e-50
Identities = 124/321 (38%), Positives = 184/321 (57%), Gaps = 22/321 (6%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
VP LS+G +P + LGTW +GK V + N A+ AGY HIDTA Y E
Sbjct: 5 VPIFTLSNGVLMPSIGLGTWQMTGEEGKTV-IRN--------AVLAGYRHIDTATLYQNE 55
Query: 90 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
Q+G AL + F+EG LKRE IFITTK + + V ALR SL+ L L+YVDLYL H
Sbjct: 56 HQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHI 115
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
P + ++ + +V D WRG LGLTK+IG+SNFN+ QI RI++ A Q
Sbjct: 116 PASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHASQ 175
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFG-----SLFPSKAQP-----DAPPPRIDDER 258
+EL+L L Q + C++++I++ AY G S+ S +P ++D+
Sbjct: 176 LELHLYLPQKAHRELCKKHNILITAYATLGSPGRMSVVGSNGRPLFESTQNSENEMNDKH 235
Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
+ ++AQKY+KT Q+ LR +E+G +V+PK+ + ER+++NI +FDF+++ E NLL++ +
Sbjct: 236 VKALAQKYSKTPAQILLRATVEMGIIVIPKTTNPERMKENINIFDFNISNAEVNLLEAHE 295
Query: 319 --TGYRTLPQTKWSKHPDYPF 337
R + HP+ PF
Sbjct: 296 RTKQERLFWWPNVADHPEDPF 316
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 199 bits (485), Expect = 1e-49
Identities = 108/287 (37%), Positives = 167/287 (58%), Gaps = 14/287 (4%)
Query: 66 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQ 124
++A A+ AGY HIDTA+ Y E VG A+ K +G+ +R+ +FI +KLW ++H E
Sbjct: 3 QRACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPED 62
Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMF--------END--TLLDNVDFLDTWRGMIDA 174
+ KSL +L L+Y+D YL+H+P+ + E D L ++D++D WRGM
Sbjct: 63 IPVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEAL 122
Query: 175 KKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAY 234
K G KSIG+SNF EQI R++ P+ Q+EL+ L Q +L +C+ +I + A+
Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAH 182
Query: 235 TPFGSL-FPSKAQ--PDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVH 291
+PFGS P + Q + P ++D +V +A+K+ +T QV LR+ I+ V+PKSV
Sbjct: 183 SPFGSPGRPLEFQTGDEDPMGLLEDPVVVDVARKHRRTPAQVLLRYHIQQDIAVIPKSVK 242
Query: 292 KERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKWSKHPDYPFQ 338
I +N ++FDF+L E+ N LKS + G+R T+ H YPF+
Sbjct: 243 PHHILENTKIFDFTLDEEDMNALKSLNRGWRACIITELEAHYFYPFK 289
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 198 bits (483), Expect = 2e-49
Identities = 106/302 (35%), Positives = 177/302 (58%), Gaps = 24/302 (7%)
Query: 26 AELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 85
AE +P + L+SG +PV+ +GT + RP V+ + A++ GY H D+A
Sbjct: 2 AEKKIPEVLLNSGHKMPVIGMGTSVESRPSNDVLA------SIFVDAIQVGYRHFDSASV 55
Query: 86 YGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 143
YG E+ +G A++K +GL R+ +FIT+K WN+ + ++PAL+ +L+ L +EYVDL
Sbjct: 56 YGTEEAIGMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDL 115
Query: 144 YLIHWPIAM---FENDTLLDNVDFLD-----TWRGMIDAKKLGLTKSIGISNFNQEQIQR 195
YLIHWP+ + EN + D L TW+ M + +LGL KSIGI N+ +++ +
Sbjct: 116 YLIHWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTK 175
Query: 196 IIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS--LFPSKAQPDAPPPR 253
+++ P+ Q+E+N + QQ L +FC++ I V A++P G+ +F
Sbjct: 176 LLEIATIPPAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSPLGAYKIFWGSGAV------ 229
Query: 254 IDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNL 313
++++ L IA KT+ QVALR++ + G+ + KS +KER++QN+++FDF L+ EE
Sbjct: 230 MENQILQDIATAKGKTIAQVALRWVYQQGSSAMAKSFNKERMKQNLEIFDFELSEEELEK 289
Query: 314 LK 315
+K
Sbjct: 290 IK 291
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 196 bits (478), Expect = 7e-49
Identities = 116/310 (37%), Positives = 172/310 (55%), Gaps = 38/310 (12%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P ++L++G +PV+ LGTWL +G +A+ A++AGY HIDTAY Y E
Sbjct: 6 PMVKLNNGLEMPVLGLGTWLSKEGEGV---------EAIKAAIDAGYRHIDTAYFYQNEK 56
Query: 91 QVGRALTKKFSEGLK-RESIFITTKLWNSYHEREQVIP-ALRKSLENLNLEYVDLYLIHW 148
+VG A+ K EG+ RE +F+TTK + + + ++P L+ +++Y+D
Sbjct: 57 EVGEAIRAKIEEGVVCREDLFVTTKFID--WDTKNLMPYDADGKLQFSDVDYID------ 108
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
TW+ M K G KSIG+SNFN EQI R++ KP Q
Sbjct: 109 ------------------TWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQ 150
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPD-APPPRIDDERLVSIAQKYN 267
+E N +L Q +L +FC+ DI + AY+P G + PD P P +DD +++ I +KYN
Sbjct: 151 VECNPSLNQRKLTEFCKNLDITLTAYSPLGRPNYYEKDPDNMPKPALDDPKVIEIGKKYN 210
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQT 327
KT QV LR+L+++G + +PKS + ERI QNI +FDF LT EE ++ F TG RT+P
Sbjct: 211 KTSGQVILRYLVDIGTIPIPKSSNSERIRQNIDIFDFKLTEEEIKIMDGFHTGQRTVPFN 270
Query: 328 KWSKHPDYPF 337
+ H +PF
Sbjct: 271 LCTSHKYFPF 280
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 194 bits (473), Expect = 3e-48
Identities = 106/300 (35%), Positives = 175/300 (58%), Gaps = 16/300 (5%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L++G IP + LGTW+ + +AV A++ GY HID A YG E +VG
Sbjct: 7 LNNGYKIPKLGLGTWMS---------ANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGD 57
Query: 95 ALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 153
+ ++G +KRE +F+TTKLW++ +E V PA +SL+ L LEY+DLY+IH P+
Sbjct: 58 GIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTAD 117
Query: 154 EN--DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
+ + + + +TWR M + GL KSIG+SNFN ++++ ++ +P+ Q E
Sbjct: 118 KKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEF 177
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
++ Q+P+L +FC++++I + Y P G+ S P AP ++E + +IA+K+NK
Sbjct: 178 HIYYQRPKLHQFCKKHNIHITGYCPLGNPGISSGVP-AP---FENEVVKAIAKKHNKKAA 233
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKWSK 331
Q+ ++F I G V+PKSVH+ERI++N ++FDF L E+ L+ D + + + K
Sbjct: 234 QICIKFSIASGHSVIPKSVHEERIKENGEVFDFELDEEDMEKLRGLDKNIKVCDMSFYFK 293
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 192 bits (469), Expect = 8e-48
Identities = 117/313 (37%), Positives = 177/313 (56%), Gaps = 20/313 (6%)
Query: 30 VPTLQLSSGGN-IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
+P + LSSGG +PV+ LGT + V+ +AV AL+ GY H DTA Y
Sbjct: 5 IPEVPLSSGGRKMPVLGLGTAADPPVDPETVR------KAVTEALKLGYRHFDTAALYNS 58
Query: 89 EDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 146
E +G A+ + EGL R+ +FIT+KLW S RE V PAL+K+L+NL LEY+D+YLI
Sbjct: 59 EQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLI 118
Query: 147 HWPIAM----FENDTLLDN---VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 199
HWP++ +E ++ +D+ W M + +KLGLTK+IG+SNF+ +++ ++ +
Sbjct: 119 HWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLAN 178
Query: 200 GLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
P+ Q+E+N QQ +L +FC+ N I+V+AY G++ + E L
Sbjct: 179 AKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYAALGAVGTFYGTNRV----MGSEVL 234
Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
IA+ TV QV LR+ E G VL KS +KER+EQN+Q+F+++L+ +E +
Sbjct: 235 NEIARIRGNTVAQVCLRWAYEQGIGVLVKSFNKERMEQNLQIFNWTLSDDESKKISEIPQ 294
Query: 320 GYRTLPQTKWSKH 332
G L S H
Sbjct: 295 GRACLGTDYTSVH 307
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 192 bits (467), Expect = 1e-47
Identities = 110/310 (35%), Positives = 171/310 (55%), Gaps = 20/310 (6%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
++ +G +P++ LGTW P G+V + AV ALEAGY H+D A Y E +
Sbjct: 3 SISFENGDEMPMIGLGTWKS--PPGEVYE-------AVTTALEAGYRHVDCAPIYKNETE 53
Query: 92 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VG AL+ F G ++R+ +++T+KLWN+ H + V PAL ++L +L L+ +DLYLIHWP+
Sbjct: 54 VGAALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPV 113
Query: 151 AMF-ENDTLLDNVDFL--------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
A+ E D DF+ +TW M KK GL + IG+SNF+ +Q I+D+G
Sbjct: 114 ALQPEVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGE 173
Query: 202 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPDAPPPRIDDERLV 260
+P Q+E++ L QPEL F ++I + AY+P GS P + D P + + +
Sbjct: 174 VRPEMNQVEMHPYLPQPELVSFAEAHNIPITAYSPLGSGDRPDAMKADDEPTLMANPTIN 233
Query: 261 SIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
IA ++ + QV L++ + G V+PKS I+ N+ D L+ +E + S D+
Sbjct: 234 DIADRHGVSPAQVLLQWGVARGTAVIPKSTTPAHIKDNLAAADLDLSADELETIDSLDSK 293
Query: 321 YRTLPQTKWS 330
YR L W+
Sbjct: 294 YRYLAGAAWT 303
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 190 bits (464), Expect = 3e-47
Identities = 105/274 (38%), Positives = 158/274 (57%), Gaps = 21/274 (7%)
Query: 66 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQ 124
E AV A++ GY HID A+ YG E +VG L +KF + KRE IFIT+KLWN+ H +
Sbjct: 13 EAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHPDD 72
Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
V A +L+NL L YVDLYL+HWP+A + L+ + G K+IG
Sbjct: 73 VEQACDITLKNLQLSYVDLYLMHWPMAYQAMEKLVTS----------------GKCKAIG 116
Query: 185 ISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 244
+SNF+ + ++R+I+ +P+ LQ+EL+ L Q +L +FC+E+++ V AY+P G+ P +
Sbjct: 117 LSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSPLGA--PDR 174
Query: 245 A-QPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFD 303
D P ++D + IA K K+ Q+ +RF +E G + +PKSV RI+ N + +
Sbjct: 175 PWVKDDDPKLMEDPIVTGIATKKGKSPAQILIRFCLERGIICIPKSVTPSRIQANFEALN 234
Query: 304 FSLTPEEFNLLKSFDTGYRTLPQTKWSKHPDYPF 337
F L PE+ L + + GYR W HP +PF
Sbjct: 235 FELDPEDLKTLLAMNIGYRGC-LLDWVNHPQHPF 267
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 190 bits (462), Expect = 6e-47
Identities = 113/291 (38%), Positives = 168/291 (57%), Gaps = 28/291 (9%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
+ T L++G IP+V GTW P G+V +V+ AL+AGY HIDTA YG
Sbjct: 7 LTDTYTLNNGTKIPIVGFGTW--QTPDGQVAY------DSVLAALKAGYRHIDTAAAYGN 58
Query: 89 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
E+ VG+A+ G+ RE +F+TTKLWN+ H + AL SL L L+YVDLYLIHW
Sbjct: 59 EESVGKAIA---DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHW 115
Query: 149 P--IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 206
P AM +N L+ DTWR M +A ++IG+SNF + + ++ + P+
Sbjct: 116 PNPAAMRDNWEQLN----ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAV 171
Query: 207 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKY 266
QI LN + + E+ + R++DI+ AY+P G+ + + P L ++A KY
Sbjct: 172 NQIFLNPSDMEDEVVAYNRKHDILSEAYSPLGT-----GKIFSIP------ELKTLADKY 220
Query: 267 NKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSF 317
+K+V QV LR+ ++ G + LPKSVH +RIEQN +LFDF L+ ++ ++ F
Sbjct: 221 DKSVAQVVLRWSLQHGFLPLPKSVHADRIEQNTELFDFELSDDDMKVIDGF 271
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 190 bits (462), Expect = 6e-47
Identities = 121/313 (38%), Positives = 172/313 (54%), Gaps = 38/313 (12%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T +L+SG NIP + LGTWL +P ++ E AV AL AGY HID A Y E++
Sbjct: 6 TFKLNSGYNIPAIGLGTWLS-KP--------HEVENAVEAALRAGYRHIDAAACYQNENE 56
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VG K G+ R+ IFIT+KLWN++H E V A+ K+L++L +Y+DLYLIHWP+A
Sbjct: 57 VGNGWKKS---GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVA 113
Query: 152 M-FENDTL-----------LDNVDFLDTWRG---MIDAKKLGLTKSIGISNFNQEQIQRI 196
N+TL L NV DTW +++AKK+ +SIGISNF Q++I +
Sbjct: 114 FEHTNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKI---RSIGISNFTQDKIDDL 170
Query: 197 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDD 256
+ + P+ QIE + LQQP L K+ +E +I+ +AY+P G+ + P +DD
Sbjct: 171 LKTAKIPPAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSPLGNNIYN------APRVVDD 224
Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
+ +IA K K + + + ++ G VLPKSV RIE N Q DF + EF L
Sbjct: 225 PDVKAIADKLGKDPAALLISWAVQRGTAVLPKSVTPSRIESNFQ--DFIIPDAEFEALNK 282
Query: 317 FDTGYRTLPQTKW 329
D R +W
Sbjct: 283 LDRNQRYNFPFRW 295
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 189 bits (461), Expect = 8e-47
Identities = 118/327 (36%), Positives = 176/327 (53%), Gaps = 30/327 (9%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
L ++G +PV+ +GTW + E A+ ALEAGY HIDTA YG E +
Sbjct: 7 LTFNNGEKMPVIGIGTWQAS---------DEEIETAIDAALEAGYRHIDTAPVYGNEKAI 57
Query: 93 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
GR L + G +KRE +FI TK+ + +V P ++KSLE+L L+YVDLYL+H P
Sbjct: 58 GRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFT 117
Query: 152 MFENDT---LLDNVDFLDT---------WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 199
+ N+ LD ++ W M + GLTKSIG+SNF+++Q+ R++ +
Sbjct: 118 ININEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKN 177
Query: 200 GLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP-----PPRI 254
+P+ QIE ++ LQQ +L FC+ +I V AY+P GS +K A P +
Sbjct: 178 CKIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLM 237
Query: 255 DDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
D + IA + KT QV LR++I+ G +PKS + R++QN+ +FDF LT EE L
Sbjct: 238 DIPEVKEIAASHGKTPAQVLLRWIIDTGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKL 297
Query: 315 KSFDTGYRTLPQTKW---SKHPDYPFQ 338
S D R + +HP++ F+
Sbjct: 298 SSLDQNIRICDFAFFHGVERHPEFTFK 324
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 188 bits (459), Expect = 1e-46
Identities = 109/326 (33%), Positives = 177/326 (54%), Gaps = 26/326 (7%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
I T+ L+SG +PV+ GTW PK + D ALEAGY HID+A +
Sbjct: 3 IADTVTLNSGYEMPVIGYGTW--QLPKNLAAERVRD-------ALEAGYRHIDSALSFKN 53
Query: 89 EDQVGRALTKKFS-EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
+++V + ++RE +F+++K+WN+YH R + + + + LE Y+DL +IH
Sbjct: 54 QEEVAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIH 113
Query: 148 WPIAMFENDT---------------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQ 192
WP E++ +VD+L+TW+ + DA + G +SIG++NFN Q
Sbjct: 114 WPFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQ 173
Query: 193 IQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPP 252
++++ GL KP+ LQ+E+N L Q E+ +FCRE I++ A+ G+ + + P
Sbjct: 174 VEQVWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPGSALYRKHEDPN 233
Query: 253 RIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFN 312
+ +E L SIA+ + K+V QV +R+ I+L L KS +RI QNI +F F LT +E
Sbjct: 234 LLYNETLQSIAKGHGKSVVQVLVRWAIDLRTTALVKSSESKRIRQNINIFKFRLTSQEIA 293
Query: 313 LLKSFDTGYRTL-PQTKWSKHPDYPF 337
+K+ + +R L P HP +P+
Sbjct: 294 RIKALNIDFRILNPLLGNYDHPYFPW 319
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 188 bits (459), Expect = 1e-46
Identities = 117/319 (36%), Positives = 165/319 (51%), Gaps = 23/319 (7%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
+ +G +P + GTW + E+A+ ALEAGY HIDTA Y E +
Sbjct: 7 ITFENGTTMPALGFGTWRAS---------DEEVEKALNEALEAGYRHIDTAPVYLNEKTI 57
Query: 93 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
G+ L + G + R+ +FI TKL V L+ SL++L LEYVDLY +H P
Sbjct: 58 GKVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFT 117
Query: 152 MFEND----------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
+ E D L D + W+ M + + GL ++IG+SNFNQ QIQRI+D+
Sbjct: 118 VPEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQ 177
Query: 202 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS 261
KP+ LQIE ++ LQQPEL KFC+ N I V AY+P GS K P +D+ +
Sbjct: 178 IKPANLQIENHIYLQQPELVKFCKANGITVTAYSPLGSKGIEKLLGREVPDLLDNPVVKD 237
Query: 262 IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321
IA+K K+ QV LR L++ G +PKS + R+ NI LF F + + L D
Sbjct: 238 IAEKLGKSPAQVLLRHLLQRGISTIPKSTNPTRLRDNIDLFGFEIDDSDMVRLNQLDQNI 297
Query: 322 RTLPQTKW---SKHPDYPF 337
R + +KHP++PF
Sbjct: 298 RICDFGFFPGITKHPEFPF 316
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 188 bits (459), Expect = 1e-46
Identities = 123/311 (39%), Positives = 180/311 (57%), Gaps = 33/311 (10%)
Query: 41 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVGRALTKK 99
IP + LGTW R + D A+ YA+ EAGY HID A Y ED VG+AL +
Sbjct: 4 IPTIGLGTWKSPR--------SEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQC 55
Query: 100 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN---- 155
+ G+KRE+I+IT+KLWN++H E V A RK+L++L L+Y+DLYL+H+P A F+N
Sbjct: 56 WDSGIKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFA-FQNTGIG 114
Query: 156 ----------DTLLDN-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-K 203
+T+ D+ V +DTW+ M + GL K IG+SN+ Q++R+ S +
Sbjct: 115 GSLNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTT 174
Query: 204 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIA 263
P Q+E NL +QQ L ++ + I+V Y+ G+ P A+PD P + DE L IA
Sbjct: 175 PYTNQVEFNLYMQQGPLREYMHKEGIIVTGYSTLGT--PDWAKPDEPVV-LKDEELNKIA 231
Query: 264 QKYNKTVPQVALRFL--IELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321
+ K+V +V L+FL IE GA +L KSV ERI +N L DF LT ++ L++ + Y
Sbjct: 232 AETGKSVGEVELKFLLTIEPGASLLAKSVTPERIYKNNHL-DFELTKDQIQRLRNRERFY 290
Query: 322 RTL-PQTKWSK 331
R + P+ W +
Sbjct: 291 RYVDPRKTWKR 301
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 188 bits (459), Expect = 1e-46
Identities = 111/314 (35%), Positives = 170/314 (54%), Gaps = 28/314 (8%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T+ LSSG +PV+ LG W + ++ ++ ++ A++ GY H D A Y E
Sbjct: 3 TVTLSSGYEMPVIGLGLWRLEK---------DELKEVILNAIKIGYRHFDCAAHYKSEAD 53
Query: 92 VGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VG AL + F GL KRE +FITTK+WNS H V+ A + SLE L ++Y+DLYL+H+P+
Sbjct: 54 VGEALAEAFKTGLVKREELFITTKIWNSDHGH--VVEACKNSLEKLQIDYLDLYLVHYPM 111
Query: 151 AMFEN-----------DTLLD---NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 196
N D +LD + TW GM LGL +SIG+SN+ +
Sbjct: 112 PTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDC 171
Query: 197 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDD 256
+ KP+ Q E + Q+ L KFC ++ ++ A+TP G +K + P +DD
Sbjct: 172 LAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPLGGAAANKDMFGSVSP-LDD 230
Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
L +A+KY K+V Q+ LR+ I+ V+PKS +R+++N+++ +F L+ E+ L+ S
Sbjct: 231 PVLNDVAKKYGKSVAQICLRWGIQRKTAVIPKSSKIQRLKENLEVLEFQLSDEDMQLIYS 290
Query: 317 FDTGYRT-LPQTKW 329
D YRT LP W
Sbjct: 291 IDRKYRTSLPSKTW 304
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 188 bits (458), Expect = 2e-46
Identities = 112/291 (38%), Positives = 170/291 (58%), Gaps = 28/291 (9%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T L++G IP + LGTWL +A + AL+ GY HIDTA YG EDQ
Sbjct: 11 TYTLNNGLKIPAIGLGTWLADEEDAAY--------KATLTALKNGYKHIDTAAAYGNEDQ 62
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VGRA+ G+ R+ IF+TTKLWN H+ + AL +SL+ L LEYVDLYLIHWP++
Sbjct: 63 VGRAIA---DSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLS 117
Query: 152 MF-ENDTLLDNVDFLDTWRGMIDAKKLG-LTKSIGISNFNQEQIQRIIDS-GLE-KPSAL 207
+ + + D+ DF+DTWR + K G K+IG+SNFN++++ ++++S G+ P
Sbjct: 118 VDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNSEGVNVVPVIN 177
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
QIE + L QP+LF + + DI + AY+P G A + ++ + IA+K+N
Sbjct: 178 QIEAHPLLTQPDLFDYLKSKDIYITAYSPLG---------HADASTLKNKVVTDIAKKHN 228
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
QV + + ++ G +V+PKS ERI NI+ F+L+ E+F+ L + +
Sbjct: 229 ANAGQVLISWGVQRGTIVIPKSTTDERIIDNIK--TFTLSQEDFDALNNLE 277
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 187 bits (455), Expect = 4e-46
Identities = 115/320 (35%), Positives = 174/320 (54%), Gaps = 29/320 (9%)
Query: 35 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
L G +P++ GTW + G+V++ A++ GY HID A YG E VG
Sbjct: 10 LPGGRKLPLLGFGTWQIKPEEVGRVIET----------AIDCGYRHIDEASLYGNEKGVG 59
Query: 94 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA- 151
+ K +G +KRE +F+T+KLW + +V P+ R+SL +L L Y+DL+LIH P +
Sbjct: 60 DGIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSA 119
Query: 152 --------MFENDTLL--DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
M +N + D +D++DTWR M GL ++IG+SNF QIQR++D
Sbjct: 120 VGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPP 179
Query: 202 EKPSA-LQIELNLNLQQPELFKFCRENDIVVMAYTPFGS---LFPSKAQPDAPPPRIDDE 257
+ P A +Q+E + L Q EL +FC++ I V AY+P GS + +A D P ++D
Sbjct: 180 KYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSPLGSPERVLQKRATTD--PLLMEDP 237
Query: 258 RLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSF 317
+ +IA+K + QV +R+ ++ G VLPKSV RI+QN + +F L+ EEF L +
Sbjct: 238 VVCAIAKKKGVSPAQVLIRYQLQRGVAVLPKSVMPSRIQQNFEALNFELSKEEFQALVNL 297
Query: 318 DTGYRTLPQTKWSKHPDYPF 337
+ YR L YPF
Sbjct: 298 NKNYRLLNFAPMKNMKYYPF 317
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 187 bits (455), Expect = 4e-46
Identities = 112/301 (37%), Positives = 168/301 (55%), Gaps = 24/301 (7%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T +L++G +IP + GTW Q N E AV+ AL AGY HIDTA YG E
Sbjct: 7 TFRLNTGEDIPAIGFGTW----------QDENAQEDAVLTALSAGYRHIDTAAVYGTEKA 56
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
+GRAL + L R+ +FIT+KLWN+ H E V A+ +SL+NL ++Y+DLYL+HWP A
Sbjct: 57 IGRALARS---RLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAA 113
Query: 152 MFENDTLLD----------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
D + ++D++DT++ M K G TK+IGISNF++ +++R+++S
Sbjct: 114 FAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCS 173
Query: 202 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS 261
P+ +Q+EL+ LQQ + ++ + I V Y+ G+ + + I+D L +
Sbjct: 174 IVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYSSLGNQNEVYSGRERYGRLIEDPALAA 233
Query: 262 IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321
I KY KT QVAL + I G VL KS RI+QN + DF L E+ +++ D
Sbjct: 234 IGTKYGKTGAQVALAWGITKGHSVLVKSKTPHRIQQNFE-SDFELKQEDMKAIENIDKKL 292
Query: 322 R 322
R
Sbjct: 293 R 293
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 186 bits (454), Expect = 6e-46
Identities = 119/326 (36%), Positives = 173/326 (53%), Gaps = 27/326 (8%)
Query: 28 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYK 85
+ V ++ L++G +P+ LGTW QV ++ E V AL+AGY IDTA+
Sbjct: 1 MTVDSIPLNTGAQLPLFGLGTW----------QVKDEAELTVALRAALDAGYRLIDTAHL 50
Query: 86 YGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 144
Y E +G+ L + S G LKRE IF+T+KL + H E V + L+ L LEY+DLY
Sbjct: 51 YQNEHIIGKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLY 110
Query: 145 LIHWPIA----------MFENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 193
LIH P + EN L + + +DTWR + K G K++G+SNF+ Q+
Sbjct: 111 LIHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQL 170
Query: 194 QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPR 253
Q + D+ KP+ Q+E ++ Q EL C++ + V AY P GS A+PD P
Sbjct: 171 QALYDAAEVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPGRKAARPDGVWPE 230
Query: 254 IDD--ERLV-SIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
D E +V +A KY+KT Q+ +R L + G +PKSV +RI +NI FDF L+ E+
Sbjct: 231 GDPLLEPIVKQLAAKYHKTAAQILIRHLTQHGISTIPKSVSPDRIVENISTFDFKLSDED 290
Query: 311 FNLLKSFDTGYRTLPQTKWSKHPDYP 336
+ L S +T R KHP +P
Sbjct: 291 MHTLNSIETRTRLFIADFAVKHPFFP 316
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 184 bits (448), Expect = 3e-45
Identities = 114/293 (38%), Positives = 160/293 (54%), Gaps = 33/293 (11%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYTHIDTAYKYG 87
++PTL LS G +IP + LG W Q+ +D I A AGY IDTA YG
Sbjct: 58 MIPTLPLSDGTSIPQLGLGVW----------QMPDDGAGVPIQAAFNAGYRAIDTAPIYG 107
Query: 88 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E+ VGRA+ + GL R+ ++ITTK+WNS + + A+R+SL L LEYVDLYLIH
Sbjct: 108 NEEGVGRAIR---ASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIH 164
Query: 148 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 207
WP+ + ++DTW+ + K GL +SIG+SNF +QR+ D P
Sbjct: 165 WPVPKIDR--------YVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVN 216
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
Q+EL+ LQQ EL F ++ IV A++P G + D L IAQK+
Sbjct: 217 QVELHPRLQQHELRAFHAKHRIVTEAWSPLGQ-----------GTLLADPVLAGIAQKHG 265
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
++ QV +R+ I+ G VV+PKSV RI +N +FDF+L E+ + S D G
Sbjct: 266 RSAAQVIIRWHIQQGLVVIPKSVTPSRIAENANVFDFTLDAEDMAAIASLDAG 318
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 183 bits (445), Expect = 7e-45
Identities = 109/281 (38%), Positives = 158/281 (56%), Gaps = 30/281 (10%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T +L++G ++P V LGTW + ++ AVI AL+ GY HID A YG E +
Sbjct: 6 TFKLNTGYDMPAVGLGTWQSKK---------DEVRDAVIAALKCGYRHIDAAAVYGNEQE 56
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VG + G+ RE IF+T+KLWN++H E V A+ KSL +L +Y+DLYLIHWP+A
Sbjct: 57 VGDGMRLS---GVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVA 113
Query: 152 ----------MFENDTLLDNVD--FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 199
+ E L+D VD DTW M + G +SIG+SNF +E+I+ ++ +
Sbjct: 114 FRYSTTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKT 173
Query: 200 GLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
P+ QIE + LQQ +L ++ + IVV Y+P G+ + P +DD +
Sbjct: 174 AKITPAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSPLGNNIYN------IPRAVDDPLV 227
Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQ 300
+ A+K NKT QV + + ++ G VVLPKSV ERIE N Q
Sbjct: 228 IETAKKLNKTPAQVLISWAVQRGTVVLPKSVTPERIESNFQ 268
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 181 bits (441), Expect = 2e-44
Identities = 109/307 (35%), Positives = 175/307 (57%), Gaps = 24/307 (7%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
+L++G +IP +ALGTW + +V N AV A+E GY HID A YG E ++G
Sbjct: 9 KLNTGASIPAMALGTWQSSKE-----EVGN----AVRLAIELGYRHIDCAEIYGNEGEIG 59
Query: 94 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
AL++ +EG +KRE +F+T+KLW H + V+PA + +L+NL L+Y+DLYLIH P+A
Sbjct: 60 EALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAF 119
Query: 153 FENDTLLDNV----------DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
+ L ++ +TW+ M GL K+IG+SNF+ +++ +++++
Sbjct: 120 KKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASI 179
Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS---LFPSKAQPDAPPPRIDDERL 259
P+ Q+EL+ L Q +L +FC I++ AY+P G+ L P K + + P +++ +
Sbjct: 180 VPACNQVELHPYLPQEKLKEFCDSKGILLTAYSPLGNPGRLVP-KERLEREPKVMEEPVI 238
Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
IA K+N +V +V LR+ I+ G VLPKS ++ + N LT +E +KS T
Sbjct: 239 KEIAAKHNCSVARVLLRWGIQRGYPVLPKSTSRDHLHDNFSALGLVLTDDEMAAIKSITT 298
Query: 320 GYRTLPQ 326
R L Q
Sbjct: 299 RQRYLTQ 305
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 181 bits (440), Expect = 3e-44
Identities = 103/315 (32%), Positives = 173/315 (54%), Gaps = 23/315 (7%)
Query: 29 IVPTLQ---LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 85
++PT+Q LS+G +P++ LGT K + QV +A+ + GY HID A
Sbjct: 15 VIPTMQYASLSNGDRMPLLGLGTG-----KSESRQVYKSVREAI----KIGYRHIDCASI 65
Query: 86 YGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 144
YG E++VG A+ + + R ++IT+KLW++ H + V AL +SL+NL ++Y++LY
Sbjct: 66 YGNEEEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLY 125
Query: 145 LIHWPIAMFENDTLLDNVDFL---------DTWRGMIDAKKLGLTKSIGISNFNQEQIQR 195
LIHWP+ + T ++VD L +TW M + GLTK IG+SNF +++Q+
Sbjct: 126 LIHWPVGIRPEKTFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQ 185
Query: 196 IIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL-FPSKAQPDAPPPRI 254
++ +KP Q+E + LQQP L ++C +I++ AY+P GS+ P + P +
Sbjct: 186 LVSHCKQKPEVNQVEHHPLLQQPTLIEYCASEEILITAYSPLGSMDRPQSLKVKDAPAVL 245
Query: 255 DDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
D + +IA+ + QV L + ++ G +PKSV R+ +N+Q D L+ E +
Sbjct: 246 DHPVIRAIAETRGCSPAQVVLAWDVQRGISAIPKSVKPSRLLENLQAADIQLSNTELQKI 305
Query: 315 KSFDTGYRTLPQTKW 329
++ D +R + W
Sbjct: 306 EALDQNFRLVNGAFW 320
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 180 bits (438), Expect = 5e-44
Identities = 115/306 (37%), Positives = 172/306 (56%), Gaps = 29/306 (9%)
Query: 28 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 87
+I T +L++G IP V LGTW G + + E A+ AL GY HIDTA+ YG
Sbjct: 1 MICKTQKLNNGKEIPTVGLGTW-GMEDEAVL-------EGAIRNALSLGYRHIDTAFIYG 52
Query: 88 IEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 146
E +G L K F EG+ +R+ +FIT+KLWN++H + LR+SL +L ++YVDLYLI
Sbjct: 53 NEKMIGNILKKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLI 110
Query: 147 HWPIAM-------FENDTLLDNV---DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 196
HWP+ E+ NV D + W+ M LGL KSIGISNF + ++I
Sbjct: 111 HWPVTFDPAPDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKI 170
Query: 197 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDD 256
+ + P+A+QIEL+ L Q EL +F + I V++Y+ GS S A+ DD
Sbjct: 171 LGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAPGSSAKVR------DD 224
Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
+ + +IA+KY Q+ L ++ G V+PKS KE + +NI L + L+ E+ + + +
Sbjct: 225 KTIKAIAKKYGCAPSQIILSYITAQGICVIPKSRSKEHLRENIDLKE--LSREDISAIDA 282
Query: 317 FDTGYR 322
+TG+R
Sbjct: 283 LNTGHR 288
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 180 bits (437), Expect = 6e-44
Identities = 106/290 (36%), Positives = 159/290 (54%), Gaps = 17/290 (5%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
VP + L G P+ A+G +G T A + ALE G+ H DTA YG E
Sbjct: 4 VPEVALRHGAGRPMPAVG--VGTADSAATSPETK--RGAALAALEVGFRHFDTAALYGTE 59
Query: 90 DQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
+G A+ + GL RE +F+TTKLW + V+P+LR+SL NL +EYVDLYL+H
Sbjct: 60 APLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVH 119
Query: 148 WPIAMFENDTLL-----DNV--DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 200
WPI++ +L D V DF WR M + +LGL K+IG+SNF + + +++
Sbjct: 120 WPISVKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVA 179
Query: 201 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLV 260
P+ Q+E+N QQ + ++C I V AY+P G D ++ L
Sbjct: 180 TIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPLGGQNWIGEGNDV----MESPVLA 235
Query: 261 SIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
IA+ K++ QV+LR++ E G +PKS +KER++QN+++FD+ LT E+
Sbjct: 236 DIARARGKSIAQVSLRWIHEQGVTPIPKSYNKERLKQNLEIFDWELTKED 285
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 178 bits (434), Expect = 1e-43
Identities = 108/297 (36%), Positives = 167/297 (56%), Gaps = 23/297 (7%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L++G +P + LGTWL + +AV ALE GY ID A Y E ++G
Sbjct: 8 LNNGKFMPAIGLGTWLA---------APGEVGKAVTLALENGYRLIDCARFYKNEKEIGE 58
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 154
+ F + RE +F+T+KLW R + + +S+++L +Y+DLYLIHWPIA+
Sbjct: 59 MGIEPFLKNHPREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKV 116
Query: 155 N-------DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 207
+ + LD +D + W+ M GL KSIG+SNF QI++I+ KP
Sbjct: 117 DASNPPKPEDFLD-MDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVIN 175
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
Q+ELN+ LQQ +L + C+ +IVV AY P G K ++ +DDE +VS+A+KYN
Sbjct: 176 QVELNVYLQQNKLREVCKSYNIVVEAYRPIGG----KPANESDKNCLDDEVVVSLAKKYN 231
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTL 324
KT Q+ LR+L++ G + +PKS + R+ QN Q+F++SL+ E+ L+ + R +
Sbjct: 232 KTTAQICLRWLVQNGIIAVPKSTNPNRLLQNYQVFEWSLSNEDMKALEKRNLNKRNV 288
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 178 bits (433), Expect = 2e-43
Identities = 124/330 (37%), Positives = 177/330 (53%), Gaps = 32/330 (9%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
+LSSG N P+V LGT H V+ E + ALE G HIDT++ Y E+ +G
Sbjct: 32 RLSSGHNFPIVGLGT---HGLNEDVL------ETVLTGALEKGIGHIDTSFVYKNEETIG 82
Query: 94 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM- 152
+ L F++G KRE IF+T+KL + E V ++ SLE L L+Y+D+YLIH P A+
Sbjct: 83 KVLKDWFAKGGKREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVH 142
Query: 153 -----FENDTLLDNVDFLDT-------WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 200
+E T D LDT W+ M K G TKSIG+SNFN+ QI I+
Sbjct: 143 HKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEA 202
Query: 201 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK----AQPDAPPPRIDD 256
KPS LQ+E++ QQ L +FC++N I+V Y P GS K Q + P +
Sbjct: 203 KIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAPLGSPGARKELHPGQMEEEFPDVFK 262
Query: 257 ERLVS-IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLK 315
+V+ IA+K+ K+V Q+ L L++ G V+ S + +++NI++FDF LT +E L
Sbjct: 263 LPVVNEIAKKHGKSVVQILLHHLVQKGIAVIFSSKNPNHLKENIEIFDFELTEDEMKSLD 322
Query: 316 SFDTGYR-TLPQTKW----SKHPDYPFQLA 340
+ D G R + K+ KH YPF A
Sbjct: 323 ALDKGERGKIFDYKFLKGIEKHQYYPFSSA 352
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 178 bits (433), Expect = 2e-43
Identities = 103/279 (36%), Positives = 160/279 (57%), Gaps = 24/279 (8%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T L++G IP++ GTW P G+V E++V+ AL GY HIDTA YG ED
Sbjct: 9 TYTLNNGVKIPIIGFGTW--QTPDGEVA------EESVLAALNCGYRHIDTASAYGNEDS 60
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VGRA+ K G+ R +FITTKLWNS H E+ A+ +SL +L L+Y+D+YLIHWP
Sbjct: 61 VGRAIQKS---GINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNP 117
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
D + ++ ++WR M +A + G ++IG+SNF + + ++++ KP QI L
Sbjct: 118 SSMRDHWAE-IN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFL 175
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
N + Q E+ ++ D++ AY+P G+ + +E + +A Y K+
Sbjct: 176 NPSDLQSEVVTENKKLDLLSEAYSPLGT-----------GGLLGNEVVKEVAANYGKSTA 224
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
QV +R+ ++ G + LPKSVH E I+ N +FDF ++PE+
Sbjct: 225 QVLIRWSLQHGFLPLPKSVHPEYIKANADVFDFEISPED 263
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 176 bits (429), Expect = 6e-43
Identities = 103/292 (35%), Positives = 167/292 (57%), Gaps = 32/292 (10%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T+ L++G ++P++ LG W GK + ++AV+ ALEAGY HIDTA Y E
Sbjct: 11 TIMLNNGISMPILGLGVW--KTKSGK------ECKEAVLNALEAGYRHIDTARIYDNEVD 62
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VG+A+ + G+ R+ IFITTKLWN+ ++ AL SL+ L +++VDLYLIH+P+
Sbjct: 63 VGQAIRES---GIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVT 119
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
+D+W+ + L K+IG+SN+ + ++ + P+ Q+E
Sbjct: 120 SKR----------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEF 169
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
+ L Q L ++C+++ I + AY+P A +I+D + IAQKY+KT
Sbjct: 170 HPFLNQIHLLEYCKKHKIQLEAYSPL-----------AHGQKIEDPTIAKIAQKYDKTPA 218
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRT 323
Q+ +R+ IE VV+PKS+ KERI +N ++FDF+++ E+ +L S D +RT
Sbjct: 219 QILIRWAIEQKIVVIPKSIKKERIIENSKVFDFAISEEDMKILNSLDEDFRT 270
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 176 bits (428), Expect = 8e-43
Identities = 106/281 (37%), Positives = 156/281 (55%), Gaps = 26/281 (9%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T L++G IP V GT+ R V EQAV A+E GY HIDTA YG E+
Sbjct: 10 TFNLNNGVKIPCVGYGTF---RTPADVA------EQAVKEAIETGYRHIDTAAVYGNEEA 60
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI- 150
VG+ + G+KRE +F+T+KLWN+ EQ A +++L+ L ++Y+DLYLIHWP
Sbjct: 61 VGKGIK---DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPAN 117
Query: 151 -AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
F +D N +TWR M D G ++IG+SNF I ++ + P+ QI
Sbjct: 118 EKQFGDDAAKINA---ETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQI 174
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
E++ E+ K+ + ++I+V A+ P G +K + + ++ IA KY KT
Sbjct: 175 EVHPGWPHTEVVKYLQAHNILVEAWAPLGGQ-GAKV--------LTNPTMIQIADKYQKT 225
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
QV LR++++ G + LPKSVHKER+ N +FDF LT E+
Sbjct: 226 PAQVCLRWVLQQGILPLPKSVHKERMISNQNIFDFELTDED 266
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 176 bits (428), Expect = 8e-43
Identities = 114/296 (38%), Positives = 161/296 (54%), Gaps = 31/296 (10%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+P++ L+ G +IPV+ LG G++ + + E++V ALEAGY IDTA YG E
Sbjct: 11 IPSVSLNDGHSIPVLGLGV-------GELSEA--EAERSVAAALEAGYRLIDTAAVYGNE 61
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
VGRA+ + G+ RE I++TTKL + A R SLE L L+YVDLYLIHWP
Sbjct: 62 AAVGRAVN---ASGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWP 118
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
D+ ++D+W G++ AK+ G+ +SIG+ NFN E + IID P+ QI
Sbjct: 119 AG--------DHGKYIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQI 170
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
EL+ L Q EL + IV AY P G +D + +AQ + KT
Sbjct: 171 ELHPLLNQAELREVNAGYGIVTEAYGPLG-----------VGRLLDHAAVTGVAQAHGKT 219
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP 325
QV LR+ I+LG VV+ +S + +RI N+++FDF LT +E L D G R P
Sbjct: 220 PAQVLLRWSIQLGNVVIARSANPDRITSNLEVFDFELTDDEMATLNGLDEGTRFRP 275
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 176 bits (428), Expect = 8e-43
Identities = 98/288 (34%), Positives = 158/288 (54%), Gaps = 32/288 (11%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
LS+G +P + +GTW + +VV + +A+ AGY H+DTA+ Y E VG+
Sbjct: 10 LSNGVQVPQLGIGTWEA-KDGNEVVNIK--------WAVNAGYRHVDTAHYYKNEKGVGQ 60
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 154
+++ G+ R IF+TTKLWN H E + A +S + L +EYVDLYLIHWP
Sbjct: 61 GISEC---GVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWPGP--- 114
Query: 155 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLN 214
N +++TWR ++ ++IG+SNF + ++ + P Q+E++ +
Sbjct: 115 ------NRSYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEMHPH 168
Query: 215 LQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVA 274
QQ L +C E +I V A+ P G + + +LV +A+K+ ++ QV
Sbjct: 169 FQQKALRAYCAEKNIAVTAWRPLGK-----------GALLTEPQLVELAEKHKRSAAQVI 217
Query: 275 LRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
+R+LI+LG + +PKS H+ERI+QN +FDF L+PE+ ++S D R
Sbjct: 218 IRWLIQLGVIAIPKSSHEERIKQNFDVFDFELSPEDMRRIESMDRNSR 265
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 176 bits (428), Expect = 8e-43
Identities = 119/320 (37%), Positives = 176/320 (55%), Gaps = 47/320 (14%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
L L++G IP + LGTW ND +AV+ AL+ GY HIDTA Y EDQV
Sbjct: 12 LSLNTGAQIPQIGLGTWQSKE---------NDAYKAVLTALKDGYRHIDTAAIYRNEDQV 62
Query: 93 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI-- 150
G+A+ G+ RE IF+TTKLW + H +V AL +SL+ L L+YVDLYL+HWP
Sbjct: 63 GQAIK---DSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARL 117
Query: 151 --AMFENDTLLD--------------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 194
A +N+ +L N +F+ TW M + K G TK++G+SNF+ ++
Sbjct: 118 DPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLK 177
Query: 195 RIIDSGLEK--PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPP 252
++ S K P+A Q+E++ L Q EL FC+ IVV AY+P GS DA P
Sbjct: 178 DLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGS-------TDA--P 228
Query: 253 RIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFN 312
+ + ++ IA+K N V + + ++ G VVLPKSV+ +RI+ N ++ F+L+ E+F
Sbjct: 229 LLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKI--FTLSTEDFE 286
Query: 313 LLK--SFDTGYRTLPQTKWS 330
+ S + G + + WS
Sbjct: 287 AINNISKEKGEKRVVHPNWS 306
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 175 bits (427), Expect = 1e-42
Identities = 90/259 (34%), Positives = 151/259 (58%), Gaps = 14/259 (5%)
Query: 62 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSY 119
+ DT A++ A+E GY H DTA Y E VG A+ + GL R +F+T+K+W S
Sbjct: 31 SEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSD 90
Query: 120 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGM 171
+V+PA R++L NL ++YVDL L+HWP+++ F + +L + D WRGM
Sbjct: 91 LHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGM 150
Query: 172 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 231
+ +LGL ++IG+SNF+ +++++++ +P+ Q+E+N QQ L + CR + +
Sbjct: 151 EECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQL 210
Query: 232 MAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVH 291
Y+P G +K P +D L IA KT+ Q+ LR+L E G V+L K+ +
Sbjct: 211 CGYSPLG----AKGTPWGSAAVMDSGVLQEIAGAKGKTLAQICLRWLYEQGDVLLVKTYN 266
Query: 292 KERIEQNIQLFDFSLTPEE 310
++R+++N+ +F++ LT EE
Sbjct: 267 EKRMKENLDIFNWELTDEE 285
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 175 bits (426), Expect = 1e-42
Identities = 107/305 (35%), Positives = 161/305 (52%), Gaps = 34/305 (11%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+P L +++G IP + LG + V DT+ A+ +AL AGY HIDTA YG E
Sbjct: 11 IPDLPMNNGHQIPQLGLGVFQ--------VDNAEDTKNAIKWALAAGYRHIDTAAYYGNE 62
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
VG A+ + + R+ IF+T+KLWNS ++ A +++L+ L L+Y+DLYLIHWP
Sbjct: 63 QWVGEAIRES---DVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP 119
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
+LD+WR M D K G K+IG+SNFNQ Q+ I+ G KP QI
Sbjct: 120 AP-----------GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQI 168
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
E + QQ ++ + I+ A++P G +A + D + +A ++ +
Sbjct: 169 ETHPYFQQNDMHAYLESQGILHEAWSPLGG-----GNNNA----LTDSVINELAAAHDVS 219
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP---Q 326
Q+ LR+ ++ VV+PKS+H+ RI+QN +F F L +E + DTG R P
Sbjct: 220 AAQIILRWHVQREEVVIPKSIHEARIQQNRDIFAFGLDEDEMKAISDLDTGKRVGPDPDD 279
Query: 327 TKWSK 331
T W K
Sbjct: 280 TAWLK 284
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 175 bits (426), Expect = 1e-42
Identities = 105/308 (34%), Positives = 174/308 (56%), Gaps = 34/308 (11%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P ++L++G IP + LG W K + + T+Q V A+ Y IDTA +YG E
Sbjct: 11 PKIKLNNGHLIPQLGLGVW-----KASLAE----TQQMVKEAIMNDYVLIDTAKQYGNEA 61
Query: 91 QVGRALTKKF-SEGLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHW 148
VG+ + F + G KR+SIF+TTK++N + +++ A+ + L+ L YVDL L+HW
Sbjct: 62 AVGQGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHW 121
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
P+ N + ++WR + D K G K+IG+ NFN E++ ++D KP+ Q
Sbjct: 122 PV----------NDKYNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQ 171
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
IE N + QP++ KFCRENDI + A++P G+ + ++ + IA ++ K
Sbjct: 172 IEFNPLIHQPKIVKFCRENDIQLEAWSPLGN-----------GRLLSNDVIKQIADEHQK 220
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTL--PQ 326
+ QV LR+ I+ G +VL K+ H +R+++N ++FDF+L+P+E + D ++ +
Sbjct: 221 SPAQVILRWEIQQGFIVLTKTTHPQRMKENAEIFDFTLSPDEMKQIDKLDQEKHSIWYDK 280
Query: 327 TKWSKHPD 334
KWS +PD
Sbjct: 281 FKWSGNPD 288
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 175 bits (425), Expect = 2e-42
Identities = 106/314 (33%), Positives = 172/314 (54%), Gaps = 31/314 (9%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
VP +++SS ++P V LG W K+ Q + QAV A++ GY H+D+A YG E
Sbjct: 7 VPGVKVSSK-SMPAVGLGLW-------KITQ--DSAAQAVYEAIKVGYRHLDSAADYGNE 56
Query: 90 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
QVG + + +EGL RE ++ITTKLWN+YH E V A R+S+++L L+Y+DLYL+H+
Sbjct: 57 QQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHF 116
Query: 149 PIAM--------------FENDT-----LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFN 189
PIA+ F++ LD V +TW M + GL + IG+ N++
Sbjct: 117 PIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYS 176
Query: 190 QEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL-FPSKAQPD 248
+ ++ KP+ LQIE + L Q L + R ++ V A++P GSL +
Sbjct: 177 AVLLHDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNMAVTAFSPLGSLSYVELNMAG 236
Query: 249 APPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTP 308
A + D +++ AQ+ T QV LR+ I+ G V+PK+ + +R+ +N+ L +F+L
Sbjct: 237 ANDTVLTDPSVLAAAQRNGVTAAQVVLRWGIQRGTAVIPKTSNPQRLIENLTLTEFTLND 296
Query: 309 EEFNLLKSFDTGYR 322
EE + + + + +R
Sbjct: 297 EEMDAISALNQNHR 310
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 175 bits (425), Expect = 2e-42
Identities = 113/321 (35%), Positives = 171/321 (53%), Gaps = 35/321 (10%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
+L+ G IP + LGT+ P G+V N+ AL+ GY HID A YG E +G
Sbjct: 18 KLNDGNQIPSIGLGTYYSENP-GEVGDAINN-------ALKNGYRHIDGAAFYGNEKVIG 69
Query: 94 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
+L + F EG +KRE IF T+KLWNS H V+ K++E+L + Y+DLYLIHWPIA
Sbjct: 70 NSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIA- 128
Query: 153 FEN----------------DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 196
FEN + ++ V +TW+ M +LGL KSIG+SNFN + + +
Sbjct: 129 FENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDL 188
Query: 197 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDD 256
+ KP Q+E++ L Q +L ++C + +I ++AY+P G + + D +
Sbjct: 189 LTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLG-----QGKCDF----FSN 239
Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
+ L SIA KY K+V V ++L + G +PKS + RI +N +FDF L+ ++ + S
Sbjct: 240 KILKSIAGKYKKSVANVIFKWLNQRGIAAIPKSGNHSRIIENFNIFDFQLSNDDIEKINS 299
Query: 317 FDTGYRTLPQTKWSKHPDYPF 337
+ RT + P Y F
Sbjct: 300 LNANIRTCSPITFFGTPFYLF 320
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 175 bits (425), Expect = 2e-42
Identities = 109/307 (35%), Positives = 168/307 (54%), Gaps = 32/307 (10%)
Query: 28 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 87
+ VP++ L+ G +IP + G + KV DT++AV ALE GY HIDTA YG
Sbjct: 1 MTVPSIVLNDGNSIPQLGYGVF-------KVPPA--DTQRAVEEALEVGYRHIDTAAIYG 51
Query: 88 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E+ VG A+ + G+ R+ +FITTKLWN H+ ++ A+ +SL L L+ VDLYL+H
Sbjct: 52 NEEGVGAAIA---ASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVH 108
Query: 148 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 207
WP +N ++ W MI+ + GLT+SIG+SN ++RI+ + P+
Sbjct: 109 WPTPAADN--------YVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVN 160
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
QIEL+ QQ E+ + +D+ + ++ P G + + D E + + A +
Sbjct: 161 QIELHPAYQQREITDWAAAHDVKIESWGPLG-----QGKYDL----FGAEPVTAAAAAHG 211
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQT 327
KT Q LR+ ++ G VV PKSV +ER+E+N+ +FDF LT E + + D G +
Sbjct: 212 KTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDAMDPGDGS---G 268
Query: 328 KWSKHPD 334
+ S HPD
Sbjct: 269 RVSAHPD 275
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 174 bits (423), Expect = 3e-42
Identities = 100/297 (33%), Positives = 163/297 (54%), Gaps = 26/297 (8%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVG 93
L SG +P V LGTW + +DT +V A+ EAGY H+DTA +YG+E +VG
Sbjct: 18 LKSGHAMPAVGLGTW----------RAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVG 67
Query: 94 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 153
+ L G+ R+ +F+T+K+W + E+V PAL +L++L L+Y+DLY IHWP +
Sbjct: 68 KGLKAAMEAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK 127
Query: 154 ENDTL------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 207
+ + + D W+ M + K GL K IG+ N+ ++ R++ S P+
Sbjct: 128 DGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVC 187
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
Q+E++ + ++F+ C+++ I V AY+P GS + A D + +A K N
Sbjct: 188 QMEMHPGWKNDKIFEACKKHGIHVTAYSPLGSSEKNLAH---------DPVVEKVANKLN 238
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTL 324
KT QV +++ ++ G V+PKS ERI++NIQ+F + + E+F +L S R L
Sbjct: 239 KTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRVL 295
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 173 bits (421), Expect = 6e-42
Identities = 114/317 (35%), Positives = 167/317 (52%), Gaps = 35/317 (11%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L++G IP + LGTW K +V E A+ E GY HIDTA+ Y ED VG
Sbjct: 36 LNNGKTIPAIGLGTW-----KSTTEEVAGAVECALT---EGGYRHIDTAFNYRNEDAVGL 87
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 154
+ + +G+KRE IF+TTK+W +YH+R V L SLE L L+YVD+ LIHWP+ +
Sbjct: 88 GIKRAMEKGVKREDIFVTTKIWVTYHDR--VEENLDMSLERLGLDYVDMLLIHWPVPLNP 145
Query: 155 N--DTLL----DNVDFLD-------TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
N D + D +D TW+ M K G TKSIG+SNF+ ++ ++
Sbjct: 146 NGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAE 205
Query: 202 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS 261
P+ Q+EL+ L Q EL +FC++N+IV+ A++PFGS+ P + +E +VS
Sbjct: 206 VVPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPFGSV---------GGPLLKNELVVS 256
Query: 262 IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSF--DT 319
+A KYN + + + I G VV+PKSV RI +N + +L+ E+ L
Sbjct: 257 LADKYNTSPGGILTSYHIGNGTVVIPKSVTNSRIVENGK-SAVTLSQEDLKALNDLHKTE 315
Query: 320 GYRTLPQTKWSKHPDYP 336
G + KW +P
Sbjct: 316 GIHRTSKPKWGVDLGFP 332
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 173 bits (421), Expect = 6e-42
Identities = 114/321 (35%), Positives = 177/321 (55%), Gaps = 47/321 (14%)
Query: 32 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 91 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 150 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
AM + + +L+ V+ DTW + K GL
Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLR------------------ 164
Query: 199 SGLEKPSALQ-IELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPDAPPPRIDD 256
KP+ Q +E + L Q +L +FC+ DIV++AY+ GS P PD P +++
Sbjct: 165 ---YKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDC-PHLLEE 220
Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
L SIA+K++++ QVALR+ ++ G VVL KS +ERI++N Q+FDF LTPE+ +K+
Sbjct: 221 PILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPED---MKA 277
Query: 317 FDTGYRTLPQTKWSKHPDYPF 337
D R L + HP +PF
Sbjct: 278 IDGLNRNLRYDNAANHPYFPF 298
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 173 bits (420), Expect = 7e-42
Identities = 90/259 (34%), Positives = 148/259 (57%), Gaps = 14/259 (5%)
Query: 62 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSY 119
+ +T A++ A+E GY H DTA Y E V A+ + GL R +F+T+KLW S
Sbjct: 33 SEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVASRADVFVTSKLWCSD 92
Query: 120 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGM 171
+V+PA R++L NL ++YVDL L+HWP + F + + D WRGM
Sbjct: 93 LHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGM 152
Query: 172 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 231
+ +LGL ++IG+SNF+ +++++++ + +P+A Q+E+N QQ L + CR + +
Sbjct: 153 EECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQL 212
Query: 232 MAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVH 291
Y+P G +K P +D L IAQ KT+ Q+ LR++ E G V+L K+ +
Sbjct: 213 CGYSPLG----AKGTPWGSAAVMDSGVLHDIAQTKGKTLAQICLRWMYEQGDVLLVKTYN 268
Query: 292 KERIEQNIQLFDFSLTPEE 310
+ R+++N+ +FD+ LT EE
Sbjct: 269 ENRMKENLDIFDWELTEEE 287
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 172 bits (419), Expect = 1e-41
Identities = 108/292 (36%), Positives = 153/292 (52%), Gaps = 26/292 (8%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
LS+G +P LG W P G+V TE AV +AL AGY HIDTA Y E+ VG
Sbjct: 11 LSNGVKMPQFGLGVW--QSPAGEV------TENAVNWALCAGYRHIDTAAIYKNEESVGA 62
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 154
L + G+ RE +FITTKLWN+ E + A +S + L ++Y+DLYLIHWP
Sbjct: 63 GLR---ASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG--- 116
Query: 155 NDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNL 213
D L + +LD+WR K ++IG+SNF+ ++ ++ P Q+EL+
Sbjct: 117 KDILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHP 176
Query: 214 NLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQV 273
Q +L FC I V A++P G + + L +I KYNKT QV
Sbjct: 177 LNNQADLRAFCDAKQIKVEAWSPLGQ-----------GKLLSNPILSAIGAKYNKTAAQV 225
Query: 274 ALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP 325
LR+ I+ + +PKSVH+ERIE+N +FDF L E+ + + +T R P
Sbjct: 226 ILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSRYGP 277
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 172 bits (418), Expect = 1e-41
Identities = 105/312 (33%), Positives = 162/312 (51%), Gaps = 29/312 (9%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
L L + +P++ GTW P G T V A++AGY HID A YG E +V
Sbjct: 4 LTLRNKQTLPLLGYGTW--ELPTGT-------TADLVETAIKAGYRHIDCAMIYGNEKEV 54
Query: 93 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
G + + +G+ KRE +F+T+KLWN+ H + V A RK+L +L L+Y+DLYLIHW +A
Sbjct: 55 GEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVA 114
Query: 152 MFENDTL--LDN--------VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
D L LD+ + +TW+ M + + GL KS+G++NF + ++
Sbjct: 115 FEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAK 174
Query: 202 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS 261
KP+ QIEL+ L Q +L FC +I V AY+PFGS P + D +
Sbjct: 175 IKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSPFGS---------TEAPVLTDPTVKE 225
Query: 262 IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321
+A+ KT QV LR+ ++ V+P+S + RI++N ++ F L+ E L + +
Sbjct: 226 VAKGLGKTPAQVLLRWAVQRNTSVIPRSSNATRIKENFEIATFELSNEHMAALNTLNRNK 285
Query: 322 RTLPQTKWSKHP 333
R + +W P
Sbjct: 286 RFVNPIEWWGFP 297
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 171 bits (417), Expect = 2e-41
Identities = 107/307 (34%), Positives = 175/307 (57%), Gaps = 29/307 (9%)
Query: 41 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 100
IP + LGT+L P V + E ++GY H+D A Y ++ +G AL++ F
Sbjct: 4 IPSIGLGTFLAEDPAALKAAVHSAIE-------DSGYRHVDCAAYYKNQEIIGEALSEIF 56
Query: 101 SEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--FENDT 157
++G +KRE ++IT+K+WN+ H + ++ ++K+L+ L LEY+DL L+HW A E+D
Sbjct: 57 AKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDE 116
Query: 158 LL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGLE-KPS 205
L +N+D L+TW+ M + LGL K IG+SNF+ EQ++R+ D G++ +P
Sbjct: 117 YLPRDETGKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPY 176
Query: 206 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQK 265
Q+E ++ LQQ + + + + +++YT G + + P + D L +A++
Sbjct: 177 CNQVESHMYLQQQPMLDYLTQRKMYMISYTCLGR---ATLKGPYGYPLLQDPVLNEVAKE 233
Query: 266 YNKTVPQVALRFLIELG--AVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRT 323
KT Q LRFL++L AVV+PKS++ I+ NI L DF LT E+F L+S G+R
Sbjct: 234 IGKTPAQTNLRFLLKLSPYAVVIPKSLNPANIKGNISL-DFDLTQEQFEKLRSRQCGWRF 292
Query: 324 L-PQTKW 329
+ P W
Sbjct: 293 VNPYPNW 299
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 171 bits (415), Expect = 3e-41
Identities = 104/291 (35%), Positives = 153/291 (52%), Gaps = 15/291 (5%)
Query: 40 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 99
+IP LGTWL KG VV AV YAL+ GY HIDTA + ED+VG+ +
Sbjct: 59 DIPAFGLGTWLAG--KGVVVP-------AVEYALKGGYRHIDTALIWRNEDEVGKGIK-- 107
Query: 100 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF-ENDTL 158
+ G+ R+ I++T KLWN+ H E V A+ S+ NL +EY+DLYLIH+P+A E +
Sbjct: 108 -ASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPETRDV 166
Query: 159 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQP 218
+N +DTW+ M + + GLT++IG SNF + I +I+ +P A + E + LQQ
Sbjct: 167 DNNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHEFETHPYLQQQ 226
Query: 219 ELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFL 278
F ++ +I V+A +P + P+ D P + DE V +A+ N TV Q L +
Sbjct: 227 SFVDFHKKENIKVIAASPLANTNPTYG--DKYPSILHDEFWVKLAEDKNATVAQTILAWG 284
Query: 279 IELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKW 329
+ G +V+ KS H I +N+ T E + D R L W
Sbjct: 285 QQRGTIVISKSTHSNHIAENLCSQGIEFTKSELEEVAKQDKKLRLLNPIHW 335
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 169 bits (410), Expect = 1e-40
Identities = 111/294 (37%), Positives = 158/294 (53%), Gaps = 32/294 (10%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQ-AVIYALEAGYTHIDTAYKYGI 88
VP + L++G +P + G W QV +D Q AV ALEAGY IDTA YG
Sbjct: 5 VPPIILNNGVEMPQLGFGVW----------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54
Query: 89 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
E+ GRA+ + GL RE +F+TTKLWNS + + A S+ L LEY+DLYLIHW
Sbjct: 55 EEGTGRAIA---ASGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHW 111
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
P+ E ++DT++ G ++IG+SNF E ++R+ P+ Q
Sbjct: 112 PMPAKER--------YVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQ 163
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
IEL+ +LQQ + E I A++P GS K D P +V+IAQK+ +
Sbjct: 164 IELHPHLQQHAAREVHAEQGIATEAWSPLGS---GKGILDIP-------AIVAIAQKHGR 213
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
T QV LR+ ++LG VV+PKSV RI++NI +F FSL E+ + + + R
Sbjct: 214 TPAQVVLRWHLQLGNVVIPKSVTPSRIKENIDVFGFSLDTEDLAAISALNEDRR 267
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 169 bits (410), Expect = 1e-40
Identities = 103/296 (34%), Positives = 159/296 (53%), Gaps = 22/296 (7%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
VP L GG+IP + GT+ ++ Q ND V AL+ GYTHIDTA Y E
Sbjct: 13 VPILNFREGGSIPQIGYGTY-------ELRQ--NDCIIGVTEALKIGYTHIDTASVYRNE 63
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+ + + + G+KRE +FIT+K+ EQ A++ L LN++Y+D LIHWP
Sbjct: 64 QDIAKVIHNP-AYGIKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP 122
Query: 150 --IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 207
+ ND + L+TW+ +I+ +K G+ K IG+SNFN +Q +I+ KP
Sbjct: 123 GVSKLPPNDPKNAQIR-LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMN 181
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
Q E++ + +FC++N I+V AY+P + + P I+ +AQKY
Sbjct: 182 QFEIHPLCFNKKTIEFCQKNGILVEAYSPLA----RQHEKVMKHPLIN-----QLAQKYK 232
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRT 323
KTV QV LR+ ++ V++PKS +RI++NI + DF+L+P+E + D T
Sbjct: 233 KTVAQVILRWALQNNMVIIPKSKTPQRIQENIDILDFALSPQELEQMNQLDENLHT 288
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 168 bits (409), Expect = 2e-40
Identities = 89/220 (40%), Positives = 135/220 (61%), Gaps = 14/220 (6%)
Query: 131 KSLENLNLEYVDLYLIHWPIAMFENDTL--LD---------NVDFLDTWRGMIDAKKLGL 179
+SL+NL L+Y+D+YL+HWP A+ E +L +D +VDF+DTW+ M + L
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330
Query: 180 TKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 239
TKSIGISNFN QI R++ S P QIE + L Q +L KFC + I V +Y+P GS
Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLGS 390
Query: 240 LFPSKA-QPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQN 298
P++ Q P I+D ++ I KY K+ Q+ LR+ ++LG VV+PKS ++ R+ +N
Sbjct: 391 --PARPWQKPGDPYVINDPKIKEIGNKYGKSPAQILLRYNVQLGNVVIPKSSNRNRLVEN 448
Query: 299 IQLFDFSLTPEEFNLLKSFDTGYRTLPQTKWSKHPDYPFQ 338
+ +FDF+L+ ++ + +FD R PQ + +HP YPF+
Sbjct: 449 MSIFDFTLSEDDMKYIGTFDCNGRICPQAEAREHPFYPFK 488
Score = 116 bits (279), Expect = 9e-25
Identities = 71/232 (30%), Positives = 131/232 (56%), Gaps = 17/232 (7%)
Query: 89 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E + G AL + G ++R+ +F+ +K + + V AL +L+ L + Y+DLYLI
Sbjct: 55 EKRFGVALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIE 113
Query: 148 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 207
P A +++ ++TW M LT++IG+SNFN +QI+RI+++ +P
Sbjct: 114 RPPACKDHN-------LIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRPQVN 166
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
QI+ + L Q +L K+C N I V++Y+P G+ + QP++ + D R+ IA++YN
Sbjct: 167 QIQCHPYLNQAKLRKYCSNNGIAVISYSPLGA--RNNIQPESLDV-LSDCRIKEIARRYN 223
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
KT ++ L++ ++LG +V+ + + ++ FDF L PE+ + + +F +
Sbjct: 224 KTPTEIVLKYNVQLGNIVI-----SDMLIESANFFDFYLAPEDMSYISTFSS 270
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 168 bits (409), Expect = 2e-40
Identities = 100/280 (35%), Positives = 161/280 (57%), Gaps = 21/280 (7%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 94 RALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
L K F + + KRE +FIT+KLW + H+ + V AL ++L++L LEYVDLYLIHWP +
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 153 ------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 206
+ + LL VD TW+ M G ++IG+SNF+ +++ +++ P+
Sbjct: 120 KKGSVGIKPENLLP-VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAV 178
Query: 207 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKY 266
Q+E + + +Q +L +FC+ + + AY+P GS + + D + + L +A+K
Sbjct: 179 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDV----LKNPILNMVAEKL 234
Query: 267 NKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSL 306
K+ QVALR+ +++G VLPKS ++ RI++N +FD+S+
Sbjct: 235 GKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 274
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 167 bits (407), Expect = 3e-40
Identities = 108/295 (36%), Positives = 154/295 (52%), Gaps = 31/295 (10%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P ++L G +P + LG W +TE AV ALE GY IDTA Y E+
Sbjct: 5 PLIKLYDGRLMPQLGLGVWQAS---------IQETELAVSKALEVGYRSIDTAAIYKNEE 55
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VG+AL + + R+ +FITTKLWN Q AL SL+ L L+YVDLYLIHWP
Sbjct: 56 GVGKALK---AAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP- 109
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
D D+ ++ WR ++ K+ GL +SIG+ NF+ +QR+ID P+ QIE
Sbjct: 110 -----DPKQDH--YVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIE 162
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTV 270
L+ LQQ +L + + I +++P D E + +AQ+YNKT
Sbjct: 163 LHPLLQQRQLHAWNATHHIATESWSPLAQ---------GGKGVFDQEIIRKLAQQYNKTP 213
Query: 271 PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP 325
Q+ +R+ ++ G +V+PKSV RI +N ++FDF L EE + D G R P
Sbjct: 214 AQIVIRWHLDSGLIVIPKSVTPARIRENFEVFDFKLQKEELLAITKLDCGKRLGP 268
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 167 bits (405), Expect = 5e-40
Identities = 98/286 (34%), Positives = 152/286 (53%), Gaps = 21/286 (7%)
Query: 64 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE--GLKRESIFITTKLWNSYHE 121
D ++A+ A++ GY DTA YG E VG A+ +K E L R+ FI +KL SYH
Sbjct: 31 DGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRDDFFIISKLSGSYHR 90
Query: 122 REQVIPALRKSLENLNLEYVDLYLIHWPIAM------FENDTLLDNVDF----LDTWRGM 171
++ V R +L+ L ++YVDLYL+H P+A+ N T L+ +D + W G+
Sbjct: 91 QDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNAIDDSIAPTEAWIGL 150
Query: 172 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 231
+ GL +SIG+SNFN+ QI ++ P+ QIE ++ Q + KFC++ +I+V
Sbjct: 151 EQCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQRPMRKFCQQQNILV 210
Query: 232 MAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVH 291
M YTP G P + + RL IA +KT QV+LR+LI+ G V + KS
Sbjct: 211 MGYTPLGK---------QKLPFLQNNRLKEIALSVDKTTAQVSLRYLIDEGVVPIVKSTD 261
Query: 292 KERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKWSKHPDYPF 337
++R ++N+ +FDF LT ++ L + R + +PF
Sbjct: 262 RKRQQENLDIFDFKLTKQQLEELDAIGGDQRACKMDFLAGAKHFPF 307
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 167 bits (405), Expect = 5e-40
Identities = 113/315 (35%), Positives = 167/315 (53%), Gaps = 41/315 (13%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
+ +L++G +IP + LGTW + K +V QAV +AL+AGY HID A Y ED+
Sbjct: 38 SFKLNTGASIPAIGLGTW-----QAKAGEV----RQAVAHALKAGYRHIDGALCYQNEDE 88
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VG + G+ R IF+T+K+W+SYH+R V L +L++L +Y+DLYLIHWP+
Sbjct: 89 VGLGIK---DSGVPRSEIFLTSKVWSSYHDR--VEECLDTTLKSLQTDYLDLYLIHWPVR 143
Query: 152 MFENDT------------LLD-NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
+ N T LD + D TW M D K G K+IG+SN I+ II
Sbjct: 144 LAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHIIK 203
Query: 199 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
+G P+ Q+EL+ Q L K+C+E I++ AY+P GS P +D
Sbjct: 204 TGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPLGS---------TSSPLHEDPD 254
Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
L+++A+K+N V + + + G VVLPKSV RIE N++ L E+ N L
Sbjct: 255 LLAVAKKHNVPTATVLISYQVNRGVVVLPKSVTPARIESNLK--TIKLDEEDMNKLDKLA 312
Query: 319 TGYRTLPQTKWSKHP 333
G + QT+++ P
Sbjct: 313 EGGK---QTRFTAPP 324
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 166 bits (403), Expect = 8e-40
Identities = 97/257 (37%), Positives = 142/257 (55%), Gaps = 21/257 (8%)
Query: 67 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVI 126
+AV AL GY IDTA Y E VGRAL G+ RE IF+TTK+WN E+ +
Sbjct: 29 EAVREALRVGYRSIDTAMIYENEAGVGRALK---DSGIPREDIFLTTKVWNKDQGYERTL 85
Query: 127 PALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGIS 186
A SL+ L ++YVDLYLIHWP+ D ++DTWR + + G K+IG+S
Sbjct: 86 AAFETSLQKLGVDYVDLYLIHWPMP--------DEDLYMDTWRALEQLYRDGKAKAIGVS 137
Query: 187 NFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQ 246
NF+ + R+++ G P+ QIEL+ L Q + FC++N IVV A++P K +
Sbjct: 138 NFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVVEAWSPL-----MKGR 192
Query: 247 PDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSL 306
P I D IA ++ KT QV LR+ ++ + +PKSV RI++N+ +FDF L
Sbjct: 193 DALTDPVITD-----IAARHGKTPAQVVLRWHLQHDIIAIPKSVTPSRIQENLDIFDFVL 247
Query: 307 TPEEFNLLKSFDTGYRT 323
+P++ + + RT
Sbjct: 248 SPDDMRQIDQLNRNERT 264
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 166 bits (403), Expect = 8e-40
Identities = 105/297 (35%), Positives = 165/297 (55%), Gaps = 36/297 (12%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L++G IP LGTW G KG + ++AV+ A+++GY ID AY YG E++VG+
Sbjct: 8 LNTGAKIPAFGLGTWQGD--KGVI-------KEAVLTAIKSGYRLIDGAYVYGNEEEVGQ 58
Query: 95 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 153
+ + S G+ KRE +F+ +K W +Y R ++ L +SL+ L L+YVDLYL+HWPI M
Sbjct: 59 GIREAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMN 116
Query: 154 E--NDT-----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 200
ND ++ + +DTW+ M G TK++G+SN+++ +++++
Sbjct: 117 PEGNDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHA 176
Query: 201 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLV 260
P+ Q+E + L Q EL FC+E I +MAY+P GS P + E +V
Sbjct: 177 TTVPAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPLGS---------TGGPLLTAEPVV 227
Query: 261 SIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSF 317
IA+K++ + V L + I G V+PKSV+ +RI+ N QL D L E+ LL +
Sbjct: 228 KIAEKHSISPAAVLLGYQIARGITVIPKSVNPDRIKANAQLKD--LDAEDMKLLNDY 282
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 165 bits (402), Expect = 1e-39
Identities = 102/301 (33%), Positives = 163/301 (54%), Gaps = 25/301 (8%)
Query: 23 PQSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDT 82
P +A VP + L+SG +PV+ GT P D + +A+ GY H+DT
Sbjct: 13 PAAAATAVPCVTLNSGHAMPVLGFGTGSSTPPA--------DLAATIAHAVRLGYRHLDT 64
Query: 83 AYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEY 140
A YG E VG A+ + G R +F+TTKL + +V+ ALR+SL L L+Y
Sbjct: 65 AAVYGTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDY 124
Query: 141 VDLYLIHWPIAMFENDTL-----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFN 189
VDL+LIHWP+A+ + D L D WRGM + +LGL +SIG+SNF+
Sbjct: 125 VDLFLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFS 184
Query: 190 QEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDA 249
++ R++ P+ Q+E+N+ +Q ++ + C E +VV AY+P G+ + DA
Sbjct: 185 AAKMSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSPLGA-HGAHWGSDA 243
Query: 250 PPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPE 309
++ L +A KT+ QVALR+L E G ++ +S ++ R++QN+ +FD+ L+ +
Sbjct: 244 V---MNSGVLHDVAAARCKTIAQVALRWLYEQGVCMVARSFNEGRMKQNMDIFDWELSDQ 300
Query: 310 E 310
+
Sbjct: 301 D 301
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 165 bits (400), Expect = 2e-39
Identities = 111/296 (37%), Positives = 159/296 (53%), Gaps = 33/296 (11%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P ++L+ G ++P + LG+W Q +T A AL+ GY IDTA Y E
Sbjct: 5 PIIRLADGNHMPQLGLGSWASDD------QQIAETIHA---ALDIGYRAIDTAAIYNNEK 55
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VG AL + + RE IF+TTKLWN H + AL +SLE L L+YVDLYLIHWP
Sbjct: 56 GVGNALQET---DIPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWPA 110
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
+ ++ W+ +I+ +K GL +SIG+SNF E IQR+I+ P QIE
Sbjct: 111 PPQDQ--------YVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIE 162
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS-IAQKYNKT 269
L+ LQQ +L + ++IV +++P AQ + D +LV + QKY KT
Sbjct: 163 LHPLLQQRQLHAWNATHNIVTESWSPL-------AQGGE---NVFDNQLVQHLTQKYGKT 212
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP 325
QV +R+ I+ G +V+PKS RI++N +FDF L E+ + + D G R P
Sbjct: 213 PAQVVIRWHIDNGMIVIPKSTTLSRIKENFDVFDFKLEKEDLTAMTTLDIGKRLGP 268
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 165 bits (400), Expect = 2e-39
Identities = 105/294 (35%), Positives = 156/294 (53%), Gaps = 32/294 (10%)
Query: 28 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKY 86
+ VPT+ L+ G IP + G V Q+ DT QAV AL+ GY HIDTA Y
Sbjct: 10 MTVPTILLNDGREIPQLGFG----------VFQIEPGDTAQAVKTALDLGYRHIDTAQMY 59
Query: 87 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 146
G E +V + + G+ R+ I++T+KL N +HE + A+ S+E L +DLYLI
Sbjct: 60 GNEAEVAQGIA---DSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLRGP-IDLYLI 115
Query: 147 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 206
HWP+ TL DF+ TW+ + +A+ G +SIG+SNF +QR+ P+
Sbjct: 116 HWPLP-----TLYGG-DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAV 169
Query: 207 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKY 266
QIE++ E+ + C E+ I V A++P A +DD + ++A +
Sbjct: 170 NQIEVHPYFGNEEVRRHCGEHQIGVEAWSPI-----------AQGKVLDDPTVTAVANRL 218
Query: 267 NKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
K+ QV LR+ +E G +V PKSV R+E+N LFDF LT E+ L+ + D G
Sbjct: 219 GKSPAQVVLRWHVERGDIVFPKSVTPSRMEENFALFDFELTEEDLALISALDKG 272
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 165 bits (400), Expect = 2e-39
Identities = 98/288 (34%), Positives = 153/288 (53%), Gaps = 28/288 (9%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
+L++ NIP + GTW P G+ A+ A++AGY HID A Y E VG
Sbjct: 6 KLNNNINIPAIGFGTW--QTPDGQTAI------NAIKTAIDAGYKHIDAAAIYKNEKGVG 57
Query: 94 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA-- 151
+ + + R+ +F+T+K+WN E + A ++ +L L+Y+DLYLIHWP A
Sbjct: 58 LGIKEA---NIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAH 114
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
FEN L+N DTW M K G K++G+SNF + + ++ KP+ QIE
Sbjct: 115 QFENWKQLNN----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEY 170
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
+ Q + +FC +N+I V ++P G + D D+E L +A KYNKTV
Sbjct: 171 HPGYMQQDCVQFCNDNNIQVEGWSPLG-------RGDV----FDNEVLKQLAHKYNKTVA 219
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
Q+++R+ I+ + LPKSV RI +N ++ DF+++ + L+ DT
Sbjct: 220 QLSIRWAIQNNVIPLPKSVTPNRIIENFEVSDFNISESDMALINKIDT 267
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 163 bits (397), Expect = 4e-39
Identities = 101/278 (36%), Positives = 152/278 (54%), Gaps = 28/278 (10%)
Query: 35 LSSGGNIPVVALGTWLGHRPKG-KVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
L+ G IP+V GT+ + +G K +Q + AL GY IDT Y E+ VG
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKSIQKS---------ALTLGYRLIDTVAIYQNEEAVG 55
Query: 94 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI-AM 152
+A+ + G+ RE IF+TTKLW +Q AL +SL L+L Y+DLYLIHWP A+
Sbjct: 56 KAIKAR---GVLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAI 112
Query: 153 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 212
D N DTWR M + + G KS+G+SNF E ++ + + PS QIE +
Sbjct: 113 NYKDWQKTNA---DTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFH 169
Query: 213 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQ 272
QP++ +FC+ + I V +++P A ++ L+ +++KY K+V Q
Sbjct: 170 PGYWQPQVTEFCKNHGIAVESWSPL-----------ARGKVFGNDLLIGLSKKYQKSVSQ 218
Query: 273 VALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
V LR++I+ + +PKS ERI++NI +FDF L+ EE
Sbjct: 219 VCLRWIIQHDVIAIPKSSSPERIKENIDVFDFELSKEE 256
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 163 bits (397), Expect = 4e-39
Identities = 107/304 (35%), Positives = 152/304 (50%), Gaps = 31/304 (10%)
Query: 36 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 95
++G IP V LGTW RP N+ AV AL AGY H+D A Y E +VG A
Sbjct: 11 ANGLRIPRVGLGTWKA-RP--------NEVRDAVRDALGAGYAHVDCAAAYANESEVGEA 61
Query: 96 LTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 154
L + F G KRE +F+T+KLWN V AL +L +L + Y+DLYLIHWP+A
Sbjct: 62 LREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKR 121
Query: 155 NDTLLDNVD--FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK--PSALQIE 210
L + + + W + GL + IG+SNFN+ Q+ + D K P+ QIE
Sbjct: 122 GTVLQPDAEASIAECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIE 181
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPF---GSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
+ L K+ + + V AY+P G LF ++E LV +A+KY
Sbjct: 182 SHPLWSNDSLVKYSQSKGLTVTAYSPLAQGGELF-------------ENEILVGLAKKYG 228
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQT 327
T QV LR+ ++ VV+PKS +RI N LF F L+ E+ + +K D ++
Sbjct: 229 VTPAQVVLRWNVQRDVVVIPKSTSAKRIASNADLFGFELSDEDMDAMKVLDV-MKSCATA 287
Query: 328 KWSK 331
WS+
Sbjct: 288 PWSE 291
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 163 bits (395), Expect = 8e-39
Identities = 102/296 (34%), Positives = 153/296 (51%), Gaps = 33/296 (11%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE-QAVIYALEAGYTHIDTAYKYGIE 89
P ++ G IP V G W QV D + V A+E GY ID AY Y E
Sbjct: 5 PVIKFHDGAQIPQVGFGIW----------QVPQDIAGETVRSAIEIGYRMIDGAYLYMNE 54
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+G L + GL R+ +F+TTK+WN+ + ++ +SL+ + +E +DL LIHWP
Sbjct: 55 AGLGEGLR---ASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP 111
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
+ D +L+TW+ D + GL +SIG SNFN + ++RII E P QI
Sbjct: 112 VP--SQDL------YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQI 163
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
ELN LQQPE+ + + +V A+TP G+ +A+P + + K+
Sbjct: 164 ELNPMLQQPEMRAVHKAHGVVTQAWTPLGNARSFEAEP-----------ITKAVARTGKS 212
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP 325
QV LR+ ++LG V+P+SV R +N+ +FDF+LT E + + + D G RT P
Sbjct: 213 PVQVILRWHVQLGNAVIPRSVKAHRQAENLDVFDFTLTEAEMSEIATLDMGLRTGP 268
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 162 bits (394), Expect = 1e-38
Identities = 104/307 (33%), Positives = 164/307 (53%), Gaps = 23/307 (7%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T +L +G +PV LGT+ KVV + + AL+ GY HIDTA Y E Q
Sbjct: 7 TTELCNGSKLPVFGLGTY-------KVVS-KEEMVTFLRTALDLGYRHIDTAIMYENEKQ 58
Query: 92 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
+G AL + + EG KRE +F+ TKL+++ + +V +R+SL+NL Y+DLYL+H+
Sbjct: 59 IGDALQEIYKEGKYKREDLFLVTKLFSN--KNTKVEDQVRQSLQNLQTNYIDLYLLHYAS 116
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
+ + L + W + + GL ++IGISNFN + + + KP QIE
Sbjct: 117 SPPTDQFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIE 176
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTV 270
+N+ QQP L +FC++ ++ V AY P ++ Q +D L ++ KY K+V
Sbjct: 177 VNVYCQQPRLLEFCKKLNLHVTAYCPL-----ARCQNTD-----NDALLTELSTKYKKSV 226
Query: 271 PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP--QTK 328
Q+ L+FL+ LG V+PK+ + ER+ +NI+ DFSL + LK + +R + +
Sbjct: 227 CQIMLQFLLSLGVSVIPKTQNLERLRENIESTDFSLDEADIAKLKGLNKNFRLIDPYDRE 286
Query: 329 WSKHPDY 335
W K Y
Sbjct: 287 WWKRVPY 293
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 162 bits (393), Expect = 1e-38
Identities = 99/287 (34%), Positives = 158/287 (55%), Gaps = 29/287 (10%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T QLS+G IP++ GT+L + D A+ AL+AGY H+D A+ YG E
Sbjct: 3 TTQLSNGVTIPMLGFGTYLID---------SKDVPAAIKTALDAGYRHLDCAHIYGNEPA 53
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VG A+ + G+ R +FIT+K+WN+ ++ + A ++L +L L+Y+DLYLIHWP
Sbjct: 54 VGEAIK---ASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWPN- 109
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
E+D L LDTWR + + ++IG+SNF+++Q++++ + KP QIE
Sbjct: 110 --EDDFELT----LDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIER 163
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
+ Q +L +F +NDIV Y+P G ++D + +A+KY K+
Sbjct: 164 HPYKVQADLGQFDTDNDIVNEGYSPIGHGHLI----------LEDPVITKLAEKYGKSPA 213
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
Q+ LR+ I+ G VV PKS R+++N ++ FSLT +E + D
Sbjct: 214 QIVLRWQIDTGFVVFPKSSKPARVKENFEISGFSLTADEIAEINGLD 260
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 162 bits (393), Expect = 1e-38
Identities = 105/301 (34%), Positives = 164/301 (54%), Gaps = 33/301 (10%)
Query: 25 SAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDT 82
S + ++L++G IP VALG V + ND TE A +A +AGY HID+
Sbjct: 11 SGNISTQRIKLNNGQEIPQVALG----------VYKAPNDGSTENACKWAFDAGYRHIDS 60
Query: 83 AYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
A +Y E+ VGRAL + E + R IFIT+KLW++ H++ A+ SL+ LN++Y+
Sbjct: 61 AARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADHDKAAA--AIEDSLKKLNVDYM 118
Query: 142 DLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
D+YL+H P M L + W+ + +A G K+IG+SNF+ E++ ++ +
Sbjct: 119 DMYLMHSPGTMGAEKRL-------EAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCR 171
Query: 202 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS 261
KP+ QIE + EL + C I + AY+P AQ A +D + +
Sbjct: 172 IKPAVNQIESHPFFAHEELREACISRGIHIQAYSPM-------AQGQA----LDRPEIKT 220
Query: 262 IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321
IA K+ KT Q+ L++ + G ++LPKS+ K RIE N QLFDF L ++ ++L + D G
Sbjct: 221 IASKHGKTPAQILLKWGLTHGNIILPKSLTKHRIESNAQLFDFELDSDDMDVLDNLDEGM 280
Query: 322 R 322
+
Sbjct: 281 K 281
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 162 bits (393), Expect = 1e-38
Identities = 104/315 (33%), Positives = 162/315 (51%), Gaps = 30/315 (9%)
Query: 28 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKY 86
+ P+ +L+SG ++P+V G W +V N+T IY A++AGY D A Y
Sbjct: 1 MTTPSTKLNSGYDMPLVGFGLW----------KVNNETCADQIYHAIKAGYRLFDGACDY 50
Query: 87 GIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL 145
G E + G+ + + EG+ KRE +FI +KLWNS+H+ ++V P RK L + L+Y DL++
Sbjct: 51 GNEVEAGKGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFI 110
Query: 146 IHWPIAM--------------FENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQ 190
+H+PIA+ EN+ L N +TW M L +SIG+SNF+
Sbjct: 111 VHFPIALKYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSA 170
Query: 191 EQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL-FPSKAQPDA 249
+ + ++ +P+ LQIE + L Q L + ++ I V AY+ FG L F DA
Sbjct: 171 QLLMDLLRYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFGPLSFVELDLKDA 230
Query: 250 --PPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLT 307
P D + + IAQK+ KT QV LR+ + V+PKS R+ QN+ + + L
Sbjct: 231 HETPKLFDHDVIKGIAQKHGKTPAQVLLRWATQRNIAVIPKSNDPTRLAQNLDVTGWDLE 290
Query: 308 PEEFNLLKSFDTGYR 322
E ++ S + R
Sbjct: 291 TSEIEVISSLNRNLR 305
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 161 bits (391), Expect = 2e-38
Identities = 106/292 (36%), Positives = 156/292 (53%), Gaps = 30/292 (10%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
VP + L++G +P++ G + P K TE+ V A++ GY IDTA Y E
Sbjct: 3 VPKVTLNNGVEMPILGYGVF--QIPPEK-------TEECVYEAIKVGYRLIDTAASYMNE 53
Query: 90 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
+ VGRA+ + EG+ +RE +F+TTKLW S E A KSL+ L LEY+DLYLIH
Sbjct: 54 EGVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQ 113
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
P D W+ M + K GL ++IG+SNF +++ ++ P+ Q
Sbjct: 114 PFG-----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQ 162
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
IE++ Q+ E +F R +I A+ PF + Q L SIA+KY K
Sbjct: 163 IEIHPFYQRQEEIEFMRNYNIQPEAWGPFAEGRKNIFQNGV---------LRSIAEKYGK 213
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
TV QV LR+L + G V +PK+V +ER+++NI +FDF LT E+ + + D G
Sbjct: 214 TVAQVILRWLTQKGIVAIPKTVRRERMKENISIFDFELTQEDMEKIATLDEG 265
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 160 bits (389), Expect = 4e-38
Identities = 99/296 (33%), Positives = 154/296 (52%), Gaps = 35/296 (11%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L++G IP + GTW K Q T AV +A++ GY HID A+ Y ED V
Sbjct: 14 LANGAQIPKLGFGTW-----KMSKEQAT----PAVAHAIKTGYRHIDCAWAYRNEDAVAA 64
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 154
+ K G+ R +++T+KLWNS+H E V AL SL++L +Y+DLYL+HWP+A
Sbjct: 65 GIKKA---GVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLN 121
Query: 155 N-DTLLDNV---------------DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
+ +++ ++ DF+ T+R M + K G ++IG+SNFN + ++D
Sbjct: 122 SKGSMVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVD 181
Query: 199 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
KP Q+E+NL + EL + + + + AY+PFGS ++D
Sbjct: 182 EASIKPVVNQVEVNLGVHNEELRNYAHAHGVTLQAYSPFGS-------NQNVAKSLEDPV 234
Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
+V +AQ+ N T QV L + + + + KSV ERIE+N ++ D L EE L
Sbjct: 235 VVDVAQRNNITPAQVLLAWTLGRDIIPISKSVTPERIEENFRVLDIQLAEEEIKHL 290
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 160 bits (389), Expect = 4e-38
Identities = 98/277 (35%), Positives = 149/277 (53%), Gaps = 28/277 (10%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
+++G IP V GTW + K ++V N AV AL GY HID A Y E +VG
Sbjct: 9 INTGAKIPAVGFGTW-----QAKPLEVEN----AVEVALREGYRHIDCAAIYRNETEVGN 59
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-- 152
+ K G+ RE IFIT KLWN+ H E V PAL K+L++L + Y+DLYL+HWP A
Sbjct: 60 GIRKS---GVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKG 116
Query: 153 ------FENDTLLD--NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 204
+D + D N+D++ T+R M G ++IG+SNFN +++ ++ P
Sbjct: 117 GDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVP 176
Query: 205 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQ 264
+ QIE + LQQP+L +FC+ I++ AY+P G+ P +DD + +A
Sbjct: 177 AVNQIEAHPYLQQPDLLQFCQSKGILIEAYSPLGN------NQTGEPRTVDDPLVHRVAG 230
Query: 265 KYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQL 301
+ + + + ++ G VVL KSV RI N+++
Sbjct: 231 ELSLDPGPLLASWGVQRGTVVLSKSVTPARIAANLRV 267
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 159 bits (387), Expect = 7e-38
Identities = 106/307 (34%), Positives = 158/307 (51%), Gaps = 35/307 (11%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
+V T L++G ++ +V GTW + Q V A+E GY H+D A Y
Sbjct: 1 MVGTTTLNTGASLELVGYGTWQA---------APGEVGQGVKVAIETGYRHLDLAKVYSN 51
Query: 89 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
+ +VG A+ + G+KRE +FIT+KLWN+ H EQV PAL +L+ L LEY+DLYLIHW
Sbjct: 52 QPEVGAAIKEA---GVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHW 108
Query: 149 PIA----------MF----ENDTLLD-NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 193
P+A +F + + LD V +DTW+ M+ G K+IG+SNF+ + +
Sbjct: 109 PVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMV 168
Query: 194 QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPR 253
II++ PS QIE + L QPEL + +I + AY+P G+ P
Sbjct: 169 DAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLGN------NTVGAPLL 222
Query: 254 IDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNL 313
+ + IA+K T QV + + I G V+PKSV RI +N + SL+ E+ +
Sbjct: 223 VQHPEIKRIAEKNGCTPAQVLIAWAIVGGHSVIPKSVTPSRIGENFK--QVSLSQEDVDA 280
Query: 314 LKSFDTG 320
+ G
Sbjct: 281 VSKLGEG 287
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 159 bits (386), Expect = 1e-37
Identities = 95/306 (31%), Positives = 170/306 (55%), Gaps = 14/306 (4%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQ 91
+QL++G +P++ LGT +P V +VT + ++ AL+ GY + DTA +Y E +
Sbjct: 15 VQLNNGYKMPLLGLGT----QPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVE 70
Query: 92 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP- 149
+G+A F +G KRE +FITTKL+ + +++ ++ SL+ L Y+DLYLI W
Sbjct: 71 IGQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLIQWSF 129
Query: 150 ---IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 206
+ F+ +++ + WR + + +LG+ +SIG++NFN + + ++ KP
Sbjct: 130 TPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVV 189
Query: 207 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS-IAQK 265
QIE+ L Q +L F + I +A +P G + P+ ++ +E + IAQK
Sbjct: 190 NQIEVTPYLPQIDLINFLKRCKIETVAISPLGRAGCFENTPEGMKIKLLEEDIFKQIAQK 249
Query: 266 YNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR--T 323
+ K+V QV LR L++ +++PK+ +R+++N ++FDF LT E+ + S + G R
Sbjct: 250 HKKSVVQVILRCLVQREIMMIPKTAKLDRLKENSEIFDFELTEEDMKQIYSLENGTRAIN 309
Query: 324 LPQTKW 329
L ++W
Sbjct: 310 LKHSQW 315
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 159 bits (386), Expect = 1e-37
Identities = 102/290 (35%), Positives = 153/290 (52%), Gaps = 27/290 (9%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
VP + L G +IP V LG L +G V V + ALEAGY HID A Y E
Sbjct: 11 VPDIALKDGHSIPQVGLGV-LRIDDEGVVPVVES--------ALEAGYRHIDGAAGYNNE 61
Query: 90 DQVGRALTKK-FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
VGRAL +++G KRE++++TTKL +S + + A SL+ L L+YVD+Y+IHW
Sbjct: 62 AGVGRALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHW 121
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
P T DTW+ + + G+ +++G+ NF ++R+ + P+ Q
Sbjct: 122 PTPFDWRST--------DTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQ 173
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
IEL+ QQ E+ FC+E+ I V AY+P A D + IA +
Sbjct: 174 IELHPTWQQREVVAFCKEHGIAVEAYSPMARGADLNA---------GDGTIEKIAAAHEV 224
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
+ QV LR+ IE G +++PKSVH +R ++N+ LF F+LT +E + + D
Sbjct: 225 SPAQVILRWHIENGTIIIPKSVHADRQKENLNLFGFALTADEHAAIDALD 274
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 159 bits (386), Expect = 1e-37
Identities = 101/292 (34%), Positives = 152/292 (52%), Gaps = 31/292 (10%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+PT L +G IPV+ GT+ KV DT AV ALE GY HIDTA YG E
Sbjct: 16 IPTFMLPTGSPIPVLGFGTY-------KVAP--EDTYDAVSRALEVGYRHIDTAQMYGNE 66
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+VG AL + G+ RE +FITTK+ NS HE ++ ++R+SLE+L +YVDL L+HWP
Sbjct: 67 AEVGAALE---ASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP 123
Query: 150 I-AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
+ ++ D L W + DA G ++IG+SN+ +E ++ + + P LQ
Sbjct: 124 LPTLYGGDVAL-------PWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVLQ 176
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
+E + +L + + +V A++P A + D LV I +
Sbjct: 177 VESHPFFPNADLRAYAQGLGMVFEAWSPL-----------ARGRAVTDPTLVEIGAELGV 225
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
QV LR+ ++ G VV PK++ +ER+ N +F FSL PE+ + + D G
Sbjct: 226 GPTQVTLRWALDRGHVVFPKTLSRERMAANFDVFSFSLDPEQTARIDALDAG 277
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 158 bits (384), Expect = 2e-37
Identities = 102/299 (34%), Positives = 167/299 (55%), Gaps = 30/299 (10%)
Query: 41 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALE-AGYTHIDTAYKYGIEDQVGRALTKK 99
IP + GT+L + P + A+ YA+E G HIDTA+ Y ++ +G L +
Sbjct: 3 IPQLGFGTYLANDPA--------KLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEI 54
Query: 100 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM----FE 154
F++G +KRE +FITTKLW ++H ++ V P L ++L L L YVDL+LIH PIA +
Sbjct: 55 FAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAK 114
Query: 155 NDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 204
+ T++ + +D L+T+ M + +K GLT+ IG+SNF+ EQ++RI + KP
Sbjct: 115 DGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKP 174
Query: 205 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQ 264
A Q+E N+ Q L +C ++I +MA+T G P P ++D + +A
Sbjct: 175 YANQVECNIYRQFKPLLSYCESHNIYLMAHTTIG--HPPLKGPFG-TSLLEDPVVKQVAS 231
Query: 265 KYNKTVPQVALRFLIELGA--VVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321
+ KT Q+ L+FL + +++P S++ + I+ N +L DF+LT ++ L+ D Y
Sbjct: 232 EAKKTSAQICLKFLQQKSKMYILIPMSMNPKNIKSNYEL-DFTLTEQQMKKLEELDRFY 289
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 158 bits (383), Expect = 2e-37
Identities = 94/244 (38%), Positives = 141/244 (57%), Gaps = 26/244 (10%)
Query: 66 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE-GLKRESIFITTK------LWNS 118
++AV A++AGY HID AY Y E +VG A+ +K E +KRE +FI +K LW +
Sbjct: 49 KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWLWTT 108
Query: 119 YHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLG 178
+ ER V A K+L++L L Y+D+YLIHWP + L+D G
Sbjct: 109 FFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKAMEELVDE----------------G 152
Query: 179 LTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 236
L K++GISNFN QI+++++ GL+ KP Q+E + L Q +L ++C I + AY+P
Sbjct: 153 LVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITITAYSP 212
Query: 237 FGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIE 296
GS A+P+ P +++ ++ IA K+ KT QV +RF I+ +V+PKSV RI
Sbjct: 213 LGSPDRPWAKPE-DPSLLEEPKIKEIAAKHKKTTAQVLIRFHIQRNVIVIPKSVTPARIV 271
Query: 297 QNIQ 300
+NIQ
Sbjct: 272 ENIQ 275
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 158 bits (383), Expect = 2e-37
Identities = 103/281 (36%), Positives = 152/281 (54%), Gaps = 24/281 (8%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
QL++G NIP VA GTW P G+ T QAV AL AGY HIDTA Y E VG
Sbjct: 9 QLANGVNIPKVAFGTW--QIPGGEA------TYQAVRAALAAGYRHIDTALAYQNEASVG 60
Query: 94 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 153
+A+ G+ RE IF+TTKL + + +SL+NL L+YVDLYL+H P
Sbjct: 61 QAIR---DSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWG 117
Query: 154 ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNL 213
+ + D + LD W+ M + G K+IG+SNF ++ I++ P QI+ L
Sbjct: 118 QVGRVYDEAN-LDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYL 176
Query: 214 NLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQV 273
+P++ KF E+ ++V AY+P A +D+ ++ + A KY +V Q+
Sbjct: 177 GFTEPKITKFSEEHAMLVEAYSPL-----------ATGGVLDNPQVQAYADKYGVSVAQL 225
Query: 274 ALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
ALRF+++ G + LPK+V+ IE N QL DF+++ + L
Sbjct: 226 ALRFVLQNGVLPLPKAVNPAHIEANTQL-DFAISVADMQAL 265
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 157 bits (380), Expect = 5e-37
Identities = 99/294 (33%), Positives = 155/294 (52%), Gaps = 27/294 (9%)
Query: 28 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKY 86
L P + L +G NIP++ LGT H + +AV+YAL E G HIDTA +Y
Sbjct: 11 LSCPAVPLHNGLNIPILGLGT--SH--------YGGYSHEAVLYALQECGIRHIDTAKRY 60
Query: 87 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 146
G E+ +G+A+T+ G++RE +++TTKLW + + A R S L ++Y+DLYL+
Sbjct: 61 GCEEALGKAVTES---GVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLM 117
Query: 147 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 206
HWP +M + L+TWR + + GL ++IG+SNF + + DSG P
Sbjct: 118 HWPDSMVPGRS--SQEVRLETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHV 175
Query: 207 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKY 266
Q+E + Q +L + CR+ +IV Y P +K Q P ++ +A+KY
Sbjct: 176 NQVEFHPFQQPMKLVEHCRKENIVFEGYCPL-----AKGQALTHP------HILELAKKY 224
Query: 267 NKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
++ Q+ +R+ I+ G V +PKS +RI +N Q+F F L E L + G
Sbjct: 225 GRSASQICIRWSIQNGVVTIPKSTKPDRIYENCQVFGFRLEDSEMAALSTLHDG 278
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 156 bits (378), Expect = 9e-37
Identities = 97/290 (33%), Positives = 160/290 (55%), Gaps = 22/290 (7%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
+L G IP++ +GT+ + + T AV A++ GY H DTA YG E+ +G
Sbjct: 7 RLRCGETIPLLGMGTYCPQKDR-------ESTISAVHQAIKIGYRHFDTAKIYGSEEALG 59
Query: 94 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
AL + S G ++R+ +F+T+KLW+S H I AL ++L+ + L+Y+D YL+HWPI +
Sbjct: 60 TALGQAISYGTVQRDDLFVTSKLWSSDHH--DPISALIQTLKTMGLDYLDNYLVHWPIKL 117
Query: 153 F--------ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 204
+ D ++ +TW+GM ++GL +SIG+SNF+ ++I ++D P
Sbjct: 118 KPGVSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSP 177
Query: 205 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQ 264
S Q+E++ +Q +L K C EN+I V Y+P G P I+ + SIA
Sbjct: 178 SVNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGG--PGNCWGSTAV--IEHPIIKSIAL 233
Query: 265 KYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
K+N T QVALR+ + GA V+ KS + R+ +N + + L ++ +L+
Sbjct: 234 KHNATPAQVALRWGMSKGASVIVKSFNGARMIENKRALEIKLDDQDLSLI 283
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 156 bits (378), Expect = 9e-37
Identities = 94/278 (33%), Positives = 146/278 (52%), Gaps = 19/278 (6%)
Query: 64 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 122
D E + A++ GY D A YG E +VGR + K EGL KRE +FI TKLWN++H +
Sbjct: 29 DAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSK 88
Query: 123 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL-----------DNVDF-----LD 166
+ V A + L++ LEY DLYLIH+PI + D + D ++F +
Sbjct: 89 QHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHE 148
Query: 167 TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRE 226
W M + LT++IG++NFN + I ++ KP+ LQIE++ L Q L K+ +E
Sbjct: 149 CWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQE 208
Query: 227 NDIVVMAYTPFG--SLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAV 284
I V AY+ FG S + + + SIA K+N Q+ LR+ ++
Sbjct: 209 QGIQVTAYSSFGPTSYVDLCESGKTYSSLLANADVKSIANKHNANTGQILLRYALDRNIA 268
Query: 285 VLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
V+PKSVH++R++ N+ + + L ++ +L S T R
Sbjct: 269 VIPKSVHEDRMKSNLDILNIQLDQDDRKILNSLKTNQR 306
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 156 bits (378), Expect = 9e-37
Identities = 103/307 (33%), Positives = 160/307 (52%), Gaps = 32/307 (10%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T L++G IP V GT+ KG +T AV AL+ GY H+D A+ Y ED+
Sbjct: 14 TYTLNTGAKIPAVGFGTFANEGAKG-------ETYAAVTKALDVGYRHLDCAWFYLNEDE 66
Query: 92 VGRALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
VG A+ + + R+ +FI TK+WN HE E V + + S ENL ++Y+DL+L+HWP
Sbjct: 67 VGDAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWP 126
Query: 150 IAMFE----------------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 193
IA + N L +N + TWR M + G+ K+IG+SN+ +
Sbjct: 127 IAAEKNADRTVKIGPDGKYVINKALTENPE--PTWRAMEELVDSGIVKAIGVSNWTIPGL 184
Query: 194 QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPR 253
+++++ KP+ QIE++ L EL +FC +NDI+ AY+P GS P
Sbjct: 185 KQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSPLGS---QNQVPTTGERV 241
Query: 254 IDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNL 313
D+ L ++A + ++ QV L + ++ G VVLPKS RIE N + + L+ E+F
Sbjct: 242 RDNPTLNAVADRRGSSLAQVLLAWGLKRGYVVLPKSSTPSRIESNFIIPE--LSEEDFAA 299
Query: 314 LKSFDTG 320
++ G
Sbjct: 300 IQKVAEG 306
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 155 bits (376), Expect = 2e-36
Identities = 98/268 (36%), Positives = 144/268 (53%), Gaps = 24/268 (8%)
Query: 58 VVQVTNDT--EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTK 114
V QVT+ +Q+V+ A+ GY IDTA YG ED VG A+ + SEGL RE +FIT+K
Sbjct: 24 VFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELFITSK 83
Query: 115 LWNSYHEREQVIPA-LRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMID 173
LW + + A + SL+ LEY DLYL+H + D+ WR + D
Sbjct: 84 LWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR-----------DYFSAWRALED 132
Query: 174 AKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMA 233
A + G K+IG+SNF + ++ KP Q+EL+ QPE + ++ A
Sbjct: 133 AYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELHPYFAQPEALATMKYYNVQPEA 192
Query: 234 YTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKE 293
+ P G + +P ++ L SIA + K++ QV LR+ I+ G VV+PKS H++
Sbjct: 193 WAPLGG---GRHKP------FENNLLQSIADAHQKSISQVILRWNIQRGVVVIPKSTHQQ 243
Query: 294 RIEQNIQLFDFSLTPEEFNLLKSFDTGY 321
RIE+N ++DFSLT +E + S D GY
Sbjct: 244 RIEENFAIWDFSLTEKEMAQISSLDLGY 271
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 155 bits (375), Expect = 2e-36
Identities = 97/272 (35%), Positives = 151/272 (55%), Gaps = 30/272 (11%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L++G +P V LG + K+ E+ V AL+AGY DTAY YG E +G
Sbjct: 8 LNNGYPMPAVGLGVY-------KIAD--EQMEEVVRTALDAGYRAFDTAYFYGNEKALGS 58
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 154
AL K S ++R+ +FIT+KLWN Y +Q I KSL+NL L+Y+DL+LIHWP E
Sbjct: 59 AL--KHSN-VERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPC---E 112
Query: 155 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLN 214
ND L ++++++ + + G K+IG+ NF +++++ P QIEL+
Sbjct: 113 NDQL-----YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPY 167
Query: 215 LQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVA 274
Q ++ FC E+DI V A+ P L +K +DD + IA +Y+KT Q+
Sbjct: 168 FNQQDVQDFCDEHDIKVTAWMP---LMRNKG-------LLDDPVITDIAHRYDKTPAQIV 217
Query: 275 LRFLIELGAVVLPKSVHKERIEQNIQLFDFSL 306
LR+ + +++PKS +RI++N +FDF+L
Sbjct: 218 LRWHLAHNRIIIPKSQTPKRIKENFDIFDFNL 249
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 154 bits (374), Expect = 3e-36
Identities = 108/316 (34%), Positives = 168/316 (53%), Gaps = 41/316 (12%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L++ IP + LGTW G + V +AV AL GY ID A+ YG E +VG
Sbjct: 14 LNTKAKIPAIGLGTW----QSGGDLCV-----EAVKRALSEGYRQIDCAHLYGNEVEVGE 64
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP-IAMF 153
AL + F+ LKRE +F+T+KL+ + + ++ ++R SL+NL + Y+DLYL+HWP I F
Sbjct: 65 ALAEAFNGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAF 124
Query: 154 ------ENDTLLDNVDFLD----TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK 203
+++ D+ FL+ W+ M +LGL ++IG+SNF +QI+ ++
Sbjct: 125 GDATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIV 184
Query: 204 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG--------SLFPSKAQPDAPPPRID 255
P+ Q++L+ +Q EL KFC+ I V A+TP G S S + + PRI
Sbjct: 185 PAVNQVKLHPFWRQDELVKFCQSKGIHVSAHTPLGVPASGPGPSDSGSGGEDEPGTPRIS 244
Query: 256 DER-------------LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLF 302
R + IA ++ KT QV LR+ ++ G VLP S+ +RI +NI +F
Sbjct: 245 FRRSRSVHGPMLKLSVVAEIADRHKKTPEQVILRWGLQRGTSVLPCSLKADRIRKNIDIF 304
Query: 303 DFSLTPEEFNLLKSFD 318
+SL+ +E N L +
Sbjct: 305 SWSLSDDECNCLNQIE 320
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 154 bits (373), Expect = 4e-36
Identities = 105/298 (35%), Positives = 159/298 (53%), Gaps = 35/298 (11%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQV 92
+LS G IP V LG V QV+ T Q ++Y ALE GY D+A Y ED V
Sbjct: 14 RLSDGTQIPSVGLG----------VYQVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGV 63
Query: 93 GRALTK--KFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLN-LEYVDLYLIHWP 149
R + K + G +RE ++ TTK+ H E +L KSL L Y+DL L+H P
Sbjct: 64 ARGIAAWLKHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAP 123
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLE-KPSAL 207
++ D L TW+ + +A G +SIG+SN+ Q+ + ++ GL+ +P
Sbjct: 124 MS--------DRTRRLGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVN 175
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
Q+E+N L + EL ++CREN+I V A++P L K R+DD L +A +Y+
Sbjct: 176 QVEINPWLCRQELVQYCRENNIAVQAFSP---LMRGK--------RLDDPILQKVAHQYD 224
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP 325
K V Q+ +R+ I++G +VLPK+ KER+ N ++DF L+ E + L D + T+P
Sbjct: 225 KGVAQILVRWSIQMGFIVLPKAAKKERLAPNFDIWDFELSAETMSELTHSDDYFVTVP 282
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 154 bits (373), Expect = 4e-36
Identities = 108/303 (35%), Positives = 157/303 (51%), Gaps = 52/303 (17%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
+ +LSSG ++P V LGTWL +P ++ E AV AL GY HID A Y E++
Sbjct: 6 SFKLSSGYDMPAVGLGTWLS-KP--------HEVENAVETALRLGYRHIDAAACYLNENE 56
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL------ 145
VG K G+ R+ IFIT+KLWN++H + V A+ K+L++L +Y+DLYL
Sbjct: 57 VGNGWKKS---GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLL 113
Query: 146 --------------IHWPIAM-FENDTL-----------LDNVDFLDTWRGMIDAKKLGL 179
IHWP+A N+TL L N+ DTW + G
Sbjct: 114 VLIHDLLSLLTNNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGK 173
Query: 180 TKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRE--NDIVVMAYTPF 237
+SIG+SNF E+I+ ++ + P+ QIE + LQQP L K+ +E +I+ +AY+P
Sbjct: 174 VRSIGVSNFTIEKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSPL 233
Query: 238 GSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQ 297
G+ + P +DD + IAQK NK + + + ++ G VLPKSV RIE
Sbjct: 234 GNNIYN------APRVVDDPTVKEIAQKLNKDPAALLISWAVQRGTSVLPKSVTPSRIES 287
Query: 298 NIQ 300
N Q
Sbjct: 288 NFQ 290
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 153 bits (371), Expect = 6e-36
Identities = 94/263 (35%), Positives = 145/263 (55%), Gaps = 30/263 (11%)
Query: 64 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 123
+ E A+ A++ GY +DTA Y E+ VG + K G+ R+ +FITTK+WN+
Sbjct: 16 EAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKC---GVPRKDLFITTKIWNNAQRLG 72
Query: 124 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 183
V A ++SL+ L L+Y+DLYLIHWP+ FL+TW+ M + G SI
Sbjct: 73 DVEGAFQRSLDRLGLDYIDLYLIHWPVPGC----------FLNTWKDMEKILESGRALSI 122
Query: 184 GISNF---NQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 240
G+SNF + E+++R+ SG+ P+ QIE + EL ++C+ NDI V AY P
Sbjct: 123 GVSNFEIRHLEELRRV--SGI-VPAVNQIECHPLCYPKELIEYCQANDIQVQAYAPL--- 176
Query: 241 FPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQ 300
A +D++ L + KY T Q+ LR+ ++ G V+PKSVH ERI N +
Sbjct: 177 --------ARGAYLDNDVLCVLGTKYAHTPAQIGLRWAVQKGISVIPKSVHPERIASNAR 228
Query: 301 LFDFSLTPEEFNLLKSFDTGYRT 323
+FDF++ E+ +LL + + Y +
Sbjct: 229 IFDFTIDQEDMDLLDTLNQNYHS 251
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 153 bits (371), Expect = 6e-36
Identities = 95/256 (37%), Positives = 141/256 (55%), Gaps = 21/256 (8%)
Query: 64 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHER 122
+T V +ALEAGY H+DTA Y E G+A+ + G RE IF+T+KL N+
Sbjct: 55 ETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKATGTSREEIFLTSKLKNN-SSY 113
Query: 123 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 182
EQ L+ SL+ +EY DLYL+H I + NV W+ + DA+ GL KS
Sbjct: 114 EQAFVDLKGSLKRSGVEYFDLYLMHSAIG---GPVIRKNV-----WKALCDAQSQGLVKS 165
Query: 183 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFP 242
IG+SNF ++ IQ ID + P+ Q++L+ ++ PE+ + C +N+I++ A+ P
Sbjct: 166 IGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPEIVEICEQNEILLEAWGPL----- 220
Query: 243 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLF 302
A R D +V IA++ K Q+ LR+ I+ G VV+PKSV ++RI N ++F
Sbjct: 221 ------ARAMRFDHPVVVKIAKEKGKDAAQIMLRWGIQHGFVVIPKSVSQKRIVSNSKIF 274
Query: 303 DFSLTPEEFNLLKSFD 318
DF L+ EE L D
Sbjct: 275 DFELSSEEMKELDGLD 290
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 153 bits (370), Expect = 8e-36
Identities = 108/306 (35%), Positives = 157/306 (51%), Gaps = 40/306 (13%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQVG 93
LS+G +IP V GT+ T D + AV+ A+ GY H DTA YG E +G
Sbjct: 10 LSNGLSIPAVGFGTYK-----------TGDGDSAVLSNAIAQGYRHFDTASFYGTETALG 58
Query: 94 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 153
+A+ + + RE F+T+KLW + + + A +LE L +Y+DLYLIHWP
Sbjct: 59 QAVAES---DIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP---- 111
Query: 154 ENDTLLDNVDFLD--TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
D L++ LD TWR + + GL ++IG+SNF ++ I+ S P Q+E
Sbjct: 112 RPDLELEDWAKLDRETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEF 171
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
+ Q E FC+ + I+V A++P G ++ + R+ E VS A
Sbjct: 172 HPGYTQDEAVAFCQNHSILVEAWSPLGR---NRLTGNGVLTRLAAEHGVSPA-------- 220
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKWS- 330
Q+ LRF ++ G + LPKS ER+ +N+ LF FSLT EE L T+PQT WS
Sbjct: 221 QICLRFALQRGVLPLPKSSSPERMAENLDLFSFSLTGEEMAALS-------TMPQTGWSG 273
Query: 331 KHPDYP 336
+HPD P
Sbjct: 274 EHPDRP 279
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 153 bits (370), Expect = 8e-36
Identities = 94/290 (32%), Positives = 154/290 (53%), Gaps = 30/290 (10%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P ++L+ G IP + LGTW P + AV+ A+E GY HIDTA KYG E
Sbjct: 5 PVIELNDGHRIPQIGLGTW----PLDD-----HQVAAAVVNAVEGGYRHIDTAVKYGNEK 55
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VG + S GL R +FITTKL + +++ + L SL+ L L+YVDL LIHWP+
Sbjct: 56 GVGNGIR---SSGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL 112
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
+ +F+ TW+ + G +SIG+SNF ++R++ + P+ QI+
Sbjct: 113 PRRD--------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQ 164
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTV 270
++ + + + R + IV +Y+P G A ++ L IAQK+ KT
Sbjct: 165 VSPAITRIVDIAYNRRHGIVTESYSPLG----------AGSDLLNAPVLGRIAQKHGKTP 214
Query: 271 PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
Q+ LR+ +E G V +PK+ + +R+++N+ +F F+L ++ + + + D G
Sbjct: 215 GQIVLRWHVEQGLVAIPKTANPQRMKENLDIFGFTLDADDTSAIATLDGG 264
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 152 bits (369), Expect = 1e-35
Identities = 97/294 (32%), Positives = 154/294 (52%), Gaps = 32/294 (10%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T++L +G +P LG + V+ N+ ++V A++ GY IDTA Y E+
Sbjct: 8 TVKLHNGVEMPWFGLGVFK--------VENGNEATESVKAAIKNGYRSIDTAAIYKNEEG 59
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VG + + G+ RE +FIT+K+WN E + A KSLE L L+Y+DLYLIHWP
Sbjct: 60 VGIGIKES---GVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP-- 114
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
+ DTWR + K G ++IG+SNF ++ ++ KP Q+E
Sbjct: 115 --------GKDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEF 166
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
+ L Q EL +C+ I + A++P + Q +D+E L IA+K+NK+V
Sbjct: 167 HPRLTQKELRDYCKAQGIQLEAWSPL-----MQGQ------LLDNEVLTQIAEKHNKSVA 215
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP 325
QV LR+ ++ V +PKS+ + RI +N +FDF L+ E+ + + + + R P
Sbjct: 216 QVILRWDLQHEVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDERVGP 269
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 152 bits (369), Expect = 1e-35
Identities = 87/259 (33%), Positives = 144/259 (55%), Gaps = 24/259 (9%)
Query: 65 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 124
T+QAV++ALE GY IDTA Y E +VG AL + + R +++ TK++++ H E+
Sbjct: 30 TKQAVLWALENGYRMIDTAASYNNEKRVGEALRES---AVPRSEVYLVTKVYHTDHGYEK 86
Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
+ A +SL L ++YVDLYLIH+P+ + +W M + + GLT+SIG
Sbjct: 87 TMKAYDRSLSALGVDYVDLYLIHFPVP----------AGVVGSWEAMAELQGKGLTRSIG 136
Query: 185 ISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 244
+SNFN ++ + + P QIE++ LQ EL FCR++ I + AY+P ++
Sbjct: 137 VSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFCRKHSIAIQAYSPL-----TR 191
Query: 245 AQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDF 304
+ ++ D L S+ KY KT QV LR+ ++ G + + KSV RI +N+ +F+F
Sbjct: 192 GE------KLHDPLLRSLGDKYGKTPAQVLLRWSLQKGYICISKSVQLSRIIENVDVFNF 245
Query: 305 SLTPEEFNLLKSFDTGYRT 323
+++ + +L + RT
Sbjct: 246 TISMADMEILDGLEENLRT 264
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 152 bits (368), Expect = 1e-35
Identities = 104/311 (33%), Positives = 160/311 (51%), Gaps = 29/311 (9%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L+ G IP + LGTW N T+ AV AL+ GY HID A YG ED+VG
Sbjct: 18 LADGSKIPGLGLGTWRSE---------PNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGD 68
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-- 152
+ + G+ R+ I++T+KLW + H E V AL K+L++L L+Y+D YLIHWP++
Sbjct: 69 GIKES---GVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKT 125
Query: 153 ----FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 204
F D + + +TW+ M + G + IG+SNFN ++RI+ KP
Sbjct: 126 GEDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKP 185
Query: 205 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQ 264
+ Q+EL+ L Q E + ++ I V AY+PFG+ + P I+ E + IA+
Sbjct: 186 AVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGN--QNTIYESKIPKLIEHETIQKIAK 243
Query: 265 KYNK--TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
+ T +A+ + I G V+PKSV+++RI+ N + LT E+ + + S R
Sbjct: 244 SKGEGVTGATIAVSWAITRGTSVIPKSVNEQRIKSNFKY--IPLTKEDMDEINSIGIRAR 301
Query: 323 TLPQTKWSKHP 333
Q +S P
Sbjct: 302 -FNQATFSNEP 311
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 151 bits (367), Expect = 2e-35
Identities = 95/293 (32%), Positives = 157/293 (53%), Gaps = 29/293 (9%)
Query: 27 ELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 86
E I+PT+ L+ G +P + GT+ K+ + D +AV A+E GY HIDTA Y
Sbjct: 8 ENIIPTITLNDGTEMPAIGFGTY-------KLRE--QDAYRAVRSAIEVGYRHIDTASLY 58
Query: 87 GIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL 145
E++VGRA+ + G + R+ +FITTK+WN H + + ++SL L L+Y+D +
Sbjct: 59 KNEEEVGRAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCM 118
Query: 146 IHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 205
+HWP + L +++++ + + LG +S+ ++NF E ++ I+ P
Sbjct: 119 VHWP---WPQKGL-----YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPV 170
Query: 206 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQK 265
Q+EL+ Q E RE +V A++P G + D+ ++ E + IAQ
Sbjct: 171 LNQVELHPGFSQAEQRAVDRELGVVTEAWSPLG-------RGDS----LNAEAITLIAQC 219
Query: 266 YNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
Y KT QV LR++ +LG V+PKS + +R +N+ +FDF L E+ N + S D
Sbjct: 220 YEKTPAQVTLRWIHQLGCSVVPKSANPQRQRENLDIFDFELNTEDMNSITSLD 272
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 151 bits (367), Expect = 2e-35
Identities = 96/286 (33%), Positives = 154/286 (53%), Gaps = 29/286 (10%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L+SG +P++ G + VQ +QAV+ A++ GY IDTA YG E +VG
Sbjct: 6 LASGIEMPLLGFGVFQ--------VQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGE 57
Query: 95 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 153
A+ + ++G+ KRE +F+T+K+W +Q A++ SL+ LNL+Y+DLYLIH P
Sbjct: 58 AILEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYN-- 115
Query: 154 ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNL 213
D WR M A + G K+IG+SNF+ Q+ + + KP QIE+N
Sbjct: 116 ---------DVFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNP 166
Query: 214 NLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQV 273
Q + + + + V A+ PF ++ + D + L IA K++K++ Q+
Sbjct: 167 FQQNKKDITYFSQYGVQVEAWAPF-----AEGKNDL----FSNILLRKIADKHHKSIAQI 217
Query: 274 ALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
LR+L + +V+ KSV ER+ QN+ +FDF LT +E +++ DT
Sbjct: 218 VLRWLTQRNIIVVAKSVKPERMAQNLDIFDFKLTHQELAEIETLDT 263
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 151 bits (366), Expect = 3e-35
Identities = 109/321 (33%), Positives = 165/321 (51%), Gaps = 35/321 (10%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L++G +P+V LG W + KV + A++ GY D A YG E +VG
Sbjct: 7 LNNGLKMPLVGLGCW---KIDKKVCA------NQIYEAIKLGYRLFDGACDYGNEKEVGE 57
Query: 95 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM- 152
+ K SEGL R+ IF+ +KLWN++H + V AL+K+L ++ L+Y+DLY IH+PIA
Sbjct: 58 GIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFK 117
Query: 153 ---FEND------TLLDN----------VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 193
FE T D+ V +DT+R + + GL KSIG+SNF I
Sbjct: 118 YVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLI 177
Query: 194 QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG--SLFPSKAQ-PDAP 250
Q ++ KP ALQIE + L Q L +FC+ +DI V+AY+ FG S Q
Sbjct: 178 QDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTT 237
Query: 251 PPRIDDERLVSIAQKY-NKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQL-FDFSLTP 308
P +++ + ++Q + T QV LR+ + G V+PKS KER+ N+++ F+LT
Sbjct: 238 PTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTE 297
Query: 309 EEFNLLKSFDTGYRTLPQTKW 329
+E + + + R W
Sbjct: 298 QELKDISALNANIRFNDPWTW 318
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 150 bits (363), Expect = 6e-35
Identities = 96/285 (33%), Positives = 152/285 (53%), Gaps = 30/285 (10%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+P + L G IP V GT+ R G ND QA+ A++ GY IDTAY Y E
Sbjct: 5 IPNVTLHDGLTIPKVGFGTY---RLNG------NDGVQAINNAIDHGYRLIDTAYNYENE 55
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
VG A+ + + RE + IT+KL YH ++ + +++SL NL+Y DLYLIHWP
Sbjct: 56 GTVGEAVRRSSTP---REQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWP 112
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
+ + D +++ W+ +I+AK+ G +SIG+ NF E ++R+ E P+ QI
Sbjct: 113 ------NPIQD--IYVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQI 164
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
EL+ Q + K+ +E+ I +++P D +D L +A +N+T
Sbjct: 165 ELHPFFNQEDQRKWHQEHQIATESWSPLA------RTNDV----LDHPVLQKLASNHNRT 214
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
V Q+ LR+ +L A+ +PKS R +NI +FDF L+ EE +++
Sbjct: 215 VSQIILRWHYQLDAIAIPKSATPSRQLENISIFDFELSDEEMSII 259
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 150 bits (363), Expect = 6e-35
Identities = 101/292 (34%), Positives = 143/292 (48%), Gaps = 35/292 (11%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDTAYKYGI 88
PT+ L+ G IP + GT+ Q+ +D T QAV AL GY HIDTA Y
Sbjct: 5 PTITLNDGRAIPAIGFGTF----------QIPDDGSTYQAVKEALVIGYRHIDTAVAYFN 54
Query: 89 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
ED+VG+A+ G+ R+ I++T+KLW + + A+ +SL L L+Y+DLYLIH
Sbjct: 55 EDEVGQAIK---DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQ 111
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
P D W+ M A+K G KSIG+SN Q+ + P+ Q
Sbjct: 112 PYG-----------DVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQ 160
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
+E N QQ L + D+ + A+ P G + + +A KY+K
Sbjct: 161 VEFNPYFQQQPLRQLLAAQDVKLEAWAPLGQ---------GNQALFKEPIIQQLAIKYHK 211
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
Q+ LRF + G +V PKSVH RI+ N +FDF LT E L++ DTG
Sbjct: 212 DAGQIILRFEHQEGVIVFPKSVHSARIKSNRDIFDFELTSTEMAQLRALDTG 263
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 150 bits (363), Expect = 6e-35
Identities = 100/295 (33%), Positives = 151/295 (51%), Gaps = 32/295 (10%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
I T +L+ G +PV+ GT+L + Q T +T A+ A +AGY DTA Y
Sbjct: 6 ITATRKLADGRQMPVMGFGTYLLND------QPTMNT--AIQTAWDAGYRMFDTAMLYRN 57
Query: 89 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
ED +G A+ + GL RE +F+T+K+ +Q + A+ SL+ L +Y+DL LIHW
Sbjct: 58 EDILGPAIQQL---GLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHW 114
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
P+ F DTWR + K G KSIG+SN+ ++ + E P Q
Sbjct: 115 PV----------REHFFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQ 164
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
+E + L Q L + +E+DIV A++P G +DD L +A +NK
Sbjct: 165 VEYHPYLNQQALADYDQEHDIVTEAWSPLGRRVV-----------LDDPMLAKMAAHHNK 213
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRT 323
+V QV LR+ ++ V +PKS H ERI++N +FDFSL +E ++ + RT
Sbjct: 214 SVAQVILRWELQHQLVTIPKSTHPERIQENANIFDFSLDIDEMTMIDLLNKNERT 268
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 150 bits (363), Expect = 6e-35
Identities = 93/285 (32%), Positives = 150/285 (52%), Gaps = 28/285 (9%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T L +G IP + LGTW P G+ T AV +AL+ GY HIDTAY Y E+
Sbjct: 7 TFVLENGVAIPKIGLGTW--QVPNGET------TYHAVSFALKNGYRHIDTAYAYHNEES 58
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH--WP 149
VG+A+ G+ R IF+T+KL ++ + +++ N LE +DLYLIH WP
Sbjct: 59 VGKAVR---DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWP 115
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
+ D +N++ W+ M + + G ++IG+SNF+ ++ ++++ KP QI
Sbjct: 116 WSEKGADYTKENIE---VWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQI 172
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
+ Q ++ FC++N I+V AY+P A +++ + IA KY KT
Sbjct: 173 RYFIGHTQEDVTAFCQDNGILVEAYSPL-----------ATGKILENAEIQKIADKYGKT 221
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
+PQV + + ++ G + LPKS H+ I QN + DF ++ E+ L
Sbjct: 222 LPQVCICYCLQKGVLPLPKSTHEAFILQNADV-DFEISSEDMQYL 265
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 149 bits (361), Expect = 1e-34
Identities = 96/298 (32%), Positives = 154/298 (51%), Gaps = 31/298 (10%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
+ T+ L++G IP + LG + P + +V E+ +I GY IDTA YG
Sbjct: 5 LADTVTLNNGTKIPGMGLGVF--QIPDEETAKVV---EEGIIN----GYRLIDTAQIYGN 55
Query: 89 EDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E G + + GL RE +F+T+K+WN++ ++ I A SLE L L+Y+DLYLIH
Sbjct: 56 ESGTGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIH 115
Query: 148 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 207
WP N + ++W+ + G K+IG+SNF ++ ++ P
Sbjct: 116 WP----------GNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVIN 165
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
Q+EL+ L Q E+ FC ++DI V A++P + Q + +E +++IA+ +N
Sbjct: 166 QVELHPKLDQKEVRDFCEKHDIKVQAWSPL-----MQGQ------LLSNETILAIAENHN 214
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP 325
K+ QV LR+ I+ ++ KSVHKER+ N +FDF L+ EE + + R P
Sbjct: 215 KSAAQVILRWDIQQDILLAVKSVHKERMISNAAVFDFELSAEEMAQINQLNESLRVGP 272
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 149 bits (361), Expect = 1e-34
Identities = 102/284 (35%), Positives = 147/284 (51%), Gaps = 33/284 (11%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L+ G IP LG + P+G+ TE AV AL GY HIDTA+ Y E VGR
Sbjct: 7 LNDGNIIPQFGLGVY--QIPEGEA------TENAVKEALRLGYRHIDTAHAYQNERSVGR 58
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 154
A+ S G+ I+IT+KLW S + + A+ + LE LNL+ +DL L+H + +
Sbjct: 59 AI---HSSGIPISEIWITSKLWPS--DYDDASQAIERMLELLNLKQIDLLLLHQQVGNYR 113
Query: 155 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLN 214
W + +A K G KSIGISNF+ E++ + + KPSALQ+E +
Sbjct: 114 K-----------AWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVETHPY 162
Query: 215 LQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVA 274
QQ EL +F + + ++ P G +D+ RL IAQKYNKTV Q+
Sbjct: 163 HQQKELQEFLKPYGTKIESWYPLGH---------GDQRLLDESRLKKIAQKYNKTVAQII 213
Query: 275 LRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
LR+ I+ G +V P+S E + +NI +FDF L+ E ++ D
Sbjct: 214 LRWHIQEGIIVFPRSTRVEHLAENINIFDFELSCTEIKEIRKLD 257
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 149 bits (360), Expect = 1e-34
Identities = 107/304 (35%), Positives = 156/304 (51%), Gaps = 41/304 (13%)
Query: 42 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
P++ GTW V N TE AV YA+E GY ID A YG E VGR + +
Sbjct: 40 PLIGFGTW------NLKVSPENTTE-AVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLK 92
Query: 102 E-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 159
GLKRE I++T+KLWN +H E V L ++L++L LEY+DLYLIHWPI N
Sbjct: 93 RAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA-- 150
Query: 160 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPE 219
N+D + T++ MI K + +IG+SNF+ Q++ ++ +G P Q+EL+ LQQ
Sbjct: 151 KNLDHVQTYKSMISLPKSRVL-NIGVSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQQSA 208
Query: 220 LFKFCRENDIVVMAYTPFG--------------------------SLFPSKAQPDAP--P 251
+ I + AY+P G SLF + P P
Sbjct: 209 WVATHKALGIKMTAYSPLGNTNPTYHSSTSPSLSSSSSFSWASWTSLFRPSSSSSKPKAP 268
Query: 252 PRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEF 311
P + + L+ IA++ N T QVAL++ + G V+PKS H+E I++N+Q + LT +
Sbjct: 269 PLLQNPILIDIAEERNCTPAQVALKWNMGRGISVIPKSSHEEWIKENLQAGECELTHADL 328
Query: 312 NLLK 315
L+
Sbjct: 329 TKLR 332
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 148 bits (359), Expect = 2e-34
Identities = 94/256 (36%), Positives = 140/256 (54%), Gaps = 25/256 (9%)
Query: 63 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 122
+ T+QAV+ A E GY IDTA Y E QVG A+ + GL R+ +FITTK +E
Sbjct: 25 DQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVK---ASGLNRDEVFITTKTMTDGYED 81
Query: 123 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 182
++ L +SL + L+Y DL LIHWP+ +D +DTW + A K G T++
Sbjct: 82 TKI--GLDESLRRIGLDYFDLVLIHWPMG---HD--------IDTWHALEAAYKAGKTRA 128
Query: 183 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFP 242
IGISNFN Q +I +P QIE +L LQQ ++ +F + +IV +Y+P G+
Sbjct: 129 IGISNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVHESYSPLGN--- 185
Query: 243 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLF 302
Q + I + L I++KY K+ QV LR+L++ V +P+S + I+ NI +F
Sbjct: 186 --GQQNL----ISNPVLKEISEKYGKSPIQVILRYLVQNDVVTIPRSTNPAHIKSNIDIF 239
Query: 303 DFSLTPEEFNLLKSFD 318
DF L ++ L+ D
Sbjct: 240 DFELDNDDLKRLRVLD 255
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 148 bits (359), Expect = 2e-34
Identities = 98/305 (32%), Positives = 159/305 (52%), Gaps = 37/305 (12%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P + L++G +P +ALG W G + + ++ + AL++GY HIDTA Y E
Sbjct: 5 PPIVLNTGARMPALALGGWAGLTEEERT-----QAKEWFLTALKSGYRHIDTAQIYYTEK 59
Query: 91 QVGRALTKKFSEGLKRESIFITTKL-WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
VG A+ + G+ RE +FITTKL WN +H R V + +KSLENL EY+DLYL+H+P
Sbjct: 60 SVGNAIRES---GIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHFP 113
Query: 150 IAMFENDT------------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 197
+F ++T ++++ D W + G K+IG+SN++ + ++ ++
Sbjct: 114 QRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELL 173
Query: 198 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDE 257
+ P+ Q+EL+ L Q +L +C+E I V AYTP G + D
Sbjct: 174 KTAKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTPTGY-----------QTVLTDP 222
Query: 258 RLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSF 317
+V +A KY + Q+ L + + G PKS ++ R ++N+ L F L PE+ + +
Sbjct: 223 TIVELAGKYGVSPAQIVLAWHLSRGVAAAPKSANESRQKENLNL-PF-LQPEDVAKISAL 280
Query: 318 DTGYR 322
D G R
Sbjct: 281 DRGQR 285
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 148 bits (359), Expect = 2e-34
Identities = 102/282 (36%), Positives = 149/282 (52%), Gaps = 33/282 (11%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L +G IP +G +L + T V AL+ GY IDTA +Y E + G
Sbjct: 12 LLNGSRIPACGVGVYL---------LPASQTAGIVEKALDVGYRLIDTAQEYENERETGE 62
Query: 95 ALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENL-NLEYVDLYLIHWPIA 151
+ + KRE + TTK+ N ++ +L++SL + +LEY+DL LIH
Sbjct: 63 GIKAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIH---- 118
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLE-KPSALQI 209
D L D ++TW+ + +A G+ KSIG+SNF + IQ + D GL+ KP QI
Sbjct: 119 ----DPLSDKKTRIETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQI 174
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
EL+ L + +L +C+ IV+ AY P + +++D LV +A+KYNKT
Sbjct: 175 ELSPWLMRKDLVDYCQNLGIVLEAYCPLTT-----------GAKLNDPTLVKLAKKYNKT 223
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEF 311
QV LR+ I+ G VV+PKS+ ER+ QN LFDF LT E+F
Sbjct: 224 PAQVLLRWNIDRGVVVIPKSLKPERLPQNFDLFDFKLTDEDF 265
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 147 bits (357), Expect = 3e-34
Identities = 103/309 (33%), Positives = 164/309 (53%), Gaps = 28/309 (9%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
IV + LSSG ++P++ GT+ +Q Q V +L G+ IDTA Y
Sbjct: 4 IVRNVCLSSGYDMPLIGFGTYK--------IQGRELVYQVVDESLNVGFRSIDTAVGYRN 55
Query: 89 EDQVGRALTKKFSE-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLI 146
E+ +G AL + L+R IFITTKL S + + + + ++KSL+ N Y+DLYLI
Sbjct: 56 EEDIGYALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLI 115
Query: 147 HWPIAMFENDTLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-KP 204
HWP A +T +N TW ++D KK G +SIG+SNF + +Q ++ + + P
Sbjct: 116 HWPGATRIPETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILP 175
Query: 205 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQ 264
+ Q+EL+ + +Q EL K+C E I + AY+ G+ + + ++ IA
Sbjct: 176 AVNQVELHPHYRQEELIKYCNEKGIHIQAYSSLGT--------SGNINLLRNPIVLKIAS 227
Query: 265 KYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTL 324
+ N + ++ L + ++ G V+PK+V+KE I+ NIQL DF + E N+L S L
Sbjct: 228 QLNVSSARLLLNWALQQGIGVIPKAVNKEHIKDNIQL-DFLIDEESMNILFS-------L 279
Query: 325 PQTKWSKHP 333
PQ K++ P
Sbjct: 280 PQIKYAWDP 288
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 147 bits (357), Expect = 3e-34
Identities = 92/250 (36%), Positives = 138/250 (55%), Gaps = 16/250 (6%)
Query: 65 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 124
T +AV ALE GY H+D A Y E+Q+ + K S G+ R+ IFIT+K+WN E
Sbjct: 38 TVEAVKTALEVGYRHLDCAEIY--ENQLSVSQGIKLS-GVNRKEIFITSKIWNDDKGYES 94
Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
A K L++L+LEY+DL LIHWPI D V+ TW+ M + G K+IG
Sbjct: 95 TKKAFHKILKDLDLEYLDLLLIHWPIGKGFKDN-WQEVN-AQTWKAMEEFYLEGKIKAIG 152
Query: 185 ISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 244
+SNF I+ + S P Q+E + QPE+ ++C++N+IVV A++PF SK
Sbjct: 153 LSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSPFSQ---SK 209
Query: 245 AQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDF 304
++++ LV +A+KY TV Q+ L ++I+ V LPKS ERI N +F+F
Sbjct: 210 V--------LENKTLVQLAKKYEVTVAQLILNWIIQKDIVPLPKSKTPERIRSNFDVFNF 261
Query: 305 SLTPEEFNLL 314
+ + ++
Sbjct: 262 GINQADLKVI 271
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 147 bits (356), Expect = 4e-34
Identities = 96/289 (33%), Positives = 152/289 (52%), Gaps = 31/289 (10%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T++L++G +P++ GT+ + + EQAV A+ AGY HIDTA Y E+
Sbjct: 3 TVKLNNGIEVPILGFGTYQ--------ITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEA 54
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VGR + + G+ R+ +FITTK+W + V+ + +SL+ L L+Y+DL LIH P
Sbjct: 55 VGRGIA---ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPYN 111
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
D W M + + G K+IG+SNF +++ + P QIE+
Sbjct: 112 -----------DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEI 160
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
N QQ + + R+ + V A+ PF ++ + D + L IA+KY K+V
Sbjct: 161 NPFQQQSKNIEALRKEGVAVEAWAPF-----AEGKNDI----FTNPILTKIAEKYGKSVA 211
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
QV LR+LIE +VL KSV ER+ QN+ +FDF L+ E+ + + + + G
Sbjct: 212 QVILRWLIEQDIIVLAKSVKPERMAQNLAVFDFELSEEDKSAIATLNQG 260
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 147 bits (356), Expect = 4e-34
Identities = 90/259 (34%), Positives = 140/259 (54%), Gaps = 23/259 (8%)
Query: 64 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 123
D E AV A++ GY H DTA YG E +G A+ K + RE FIT+K+WN+ H E
Sbjct: 31 DFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAIEKS---QIPREEFFITSKVWNTDHGYE 87
Query: 124 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 183
A ++ + LN+EY+D+YLIH+ + + L+TW M + G K I
Sbjct: 88 ATKKAFEQTCKKLNVEYLDMYLIHFASSYY-----------LETWHAMEELYLQGKIKVI 136
Query: 184 GISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPS 243
G++NF + ++ ++ P QIE + Q EL ++ ++ I+ A+ P G +
Sbjct: 137 GVANFQIQHLEELMKHSRITPMINQIETHPEFPQNELHQYLTKHKILHEAWAPLGQ--GN 194
Query: 244 KAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFD 303
KA +++ L IA + KTV QV LR+ I+ G +++PKS + +RI++NIQLFD
Sbjct: 195 KAL-------LENTVLKKIASNHEKTVAQVILRWHIQRGIIIIPKSSNPKRIKENIQLFD 247
Query: 304 FSLTPEEFNLLKSFDTGYR 322
F L+ EE + +TG R
Sbjct: 248 FELSSEEMEKINQLNTGKR 266
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 147 bits (355), Expect = 5e-34
Identities = 93/279 (33%), Positives = 153/279 (54%), Gaps = 28/279 (10%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGIEDQVG 93
L++G IP + LGTWL + ND V+ A+ GY DTA YG E VG
Sbjct: 9 LNNGEKIPQIQLGTWL----------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVG 58
Query: 94 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 153
+ + ++ ++R IF+TTKL + + E A+ +L+ LEY+DL LIH P
Sbjct: 59 KGI---WNSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWI 115
Query: 154 ENDTLLDN--VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
E + D L+ WR M +A K G +SIG+SNF QE I+ I+++G P+ QIE+
Sbjct: 116 EVNRTNDRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEV 175
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
++ EL +C++ I + AY+P L K ++D+++++ A+KYN T
Sbjct: 176 HIGKVPVELMDYCKKLGIKIEAYSP---LSHGKL--------LNDDQIIAYAKKYNVTPA 224
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
Q+ L F ++LG +V+PKS + +++N+ + +F ++ E+
Sbjct: 225 QLMLAFDMQLGCIVIPKSDNVTEMKENLNI-NFKISDED 262
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 146 bits (354), Expect = 7e-34
Identities = 95/291 (32%), Positives = 152/291 (52%), Gaps = 34/291 (11%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN-DTEQAVIYALEAGYTHIDTAYKYGI 88
VPTL+++ G P + LG W Q+++ DT +V A+E GY HIDTA YG
Sbjct: 8 VPTLEMNDGKTTPQLGLGVW----------QLSDEDTYTSVRAAIETGYRHIDTAAIYGN 57
Query: 89 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E+ VGRA+ G ++RE +FITTKLWN+ ++ A +S + L ++YVDLYL+H
Sbjct: 58 EEAVGRAVADAVKAGDVQREELFITTKLWNA--DQACGKEAFAESQKKLGMDYVDLYLLH 115
Query: 148 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 207
WP ++ F+ + M + ++ G SIG+ NF E + + +G P+
Sbjct: 116 WPCPQADS--------FVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQAG-HTPAVN 166
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
QIE++ Q E R+ IV A++P G + D + IA ++
Sbjct: 167 QIEIHPGFSQAEQRSDNRDRGIVTEAWSPLGQ-----------GQNLTDPTIAKIAAEHG 215
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
+V Q +R+ I+ G VV+P+S ER+ QN +F F L+ +E + +++ D
Sbjct: 216 VSVAQAIIRWHIQRGDVVIPRSSKVERVRQNFDVFGFELSADEVSAIEALD 266
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 146 bits (354), Expect = 7e-34
Identities = 96/300 (32%), Positives = 153/300 (51%), Gaps = 33/300 (11%)
Query: 39 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 98
G+IP + GT + + T D AL AG+ H D A +Y E +VG AL
Sbjct: 18 GHIPALGFGTLIAD--PALTITATRD-------ALAAGFRHFDCAERYRNEREVGEALRA 68
Query: 99 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM----- 152
+ G + RE IF+TTKLWN+ H E+V PA SL+ L L+Y+DLYLIH P A
Sbjct: 69 GRAAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDE 128
Query: 153 ----FENDTLL--DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 206
+N +++ + V +TW + + G ++IG+S+ + +++ I ++ KP+
Sbjct: 129 QDPRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAV 188
Query: 207 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKY 266
+Q+E + L + EL +FC+ N IV++A+ P G P ++D + S++++
Sbjct: 189 VQVESHPYLPETELLEFCKRNGIVLLAFAPLGH--------GMRPGLLEDPVITSVSERV 240
Query: 267 NKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE-FNLLKSFDTGYRTLP 325
KT QV L + ++ G +L R ++N FD S PEE FN + T R P
Sbjct: 241 GKTAAQVLLSWAVQRGTALLTTPRSAARAKEN---FDISPLPEEAFNEINRIQTRQRLNP 297
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 146 bits (354), Expect = 7e-34
Identities = 104/301 (34%), Positives = 166/301 (55%), Gaps = 42/301 (13%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
LS+G IP + LGT P ++ ++ VI A++AGY HIDTA+ YG E+ +G+
Sbjct: 12 LSNGKTIPALGLGTVPPEDP--------HELKEQVITAVKAGYRHIDTAWYYGTEEYIGQ 63
Query: 95 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 153
AL + F EG+ KRE +FITTK+W S+ + +L KSL +L L+YVDL+L HWP+ +
Sbjct: 64 ALKQLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLH 121
Query: 154 --EN----------------DTLLDNVDFLDTWRGMID-AKKLGLTKSIGISNFNQEQIQ 194
EN D + + ++D + + D KSIG+SN++ +++
Sbjct: 122 GDENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLR 181
Query: 195 RIIDS-GLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPR 253
+++ + KP QIE + L Q +L K+C +N + + AY+P GS AP +
Sbjct: 182 KLLAAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAYSPVGS-------NGAPVLK 234
Query: 254 IDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNL 313
+ + + +A KY+ +V ++A + I G VLP+S + ERI+ I+L +LT EE N
Sbjct: 235 L--QLINELASKYDVSVNEIANAYHILQGRSVLPRSSNLERIKSIIRL--PNLTTEELNA 290
Query: 314 L 314
L
Sbjct: 291 L 291
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 146 bits (353), Expect = 1e-33
Identities = 103/293 (35%), Positives = 152/293 (51%), Gaps = 42/293 (14%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
TL+L++G IP V LGTW R K N+ +AVI AL+AGY HID A YG E +
Sbjct: 10 TLKLNTGQTIPQVGLGTW---RSK------ENEGYKAVIEALKAGYRHIDGAAVYGNEGE 60
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VG+A+ G+ R IF+TTKLW ++ Q AL +SL+ L L+YV LYL+HWP+
Sbjct: 61 VGKAIQ---DSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVP 115
Query: 152 M----FENDTLLD---------NVD----FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 194
+ ++ L +VD F+ TW M + G TK+IG+SNF+ ++
Sbjct: 116 LRTENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLK 175
Query: 195 RIIDSGLEK--PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPP 252
++ + K P+ Q+E + L Q EL ++C E IV+ AY+P G P
Sbjct: 176 DLLAAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYSPLGG---------ENAP 226
Query: 253 RIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFS 305
+ D + IA+ V + + ++ G V LPKSV RI N+++ S
Sbjct: 227 ILSDPTVQEIAKANGVEAGHVVISWAVQKGLVTLPKSVTPSRIVGNLKVLTLS 279
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 145 bits (352), Expect = 1e-33
Identities = 94/266 (35%), Positives = 136/266 (51%), Gaps = 27/266 (10%)
Query: 68 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVI 126
AV A+E G+ H DTAY Y E ++G AL + G + RE+IF+TTKLWN++H+ V
Sbjct: 49 AVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVR 108
Query: 127 PALRKSLENLNLEYVDLYLIHWPIA-----------MFENDTLLDNVDFLDTWRGMIDAK 175
K LE L Y+DLYL+H+P+ M ++ +D+LDTWR M +
Sbjct: 109 RICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLV 168
Query: 176 KLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYT 235
KLG+ +SIG+SNFN EQIQRII KP Q+E+ Q +L +CR N +
Sbjct: 169 KLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYNGNYCDSLF 228
Query: 236 PFGSLFPSKAQPDA-PPPRIDDERLVSIAQKYNKTVP-------------QVALRFL-IE 280
S K+ P R + + L S + K V + +R L I+
Sbjct: 229 TSWSTKQKKSLPSVFLFGRCETDWLRSTSALQVKLVAIFGSIFISIRLNLNINIRILEID 288
Query: 281 LGAVVLPKSVHKERIEQNIQLFDFSL 306
G V +PK+ + I++N+ +FDF L
Sbjct: 289 YGVVPIPKAANPIHIKENLNIFDFKL 314
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 145 bits (351), Expect = 2e-33
Identities = 102/327 (31%), Positives = 171/327 (52%), Gaps = 51/327 (15%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIED 90
+ +L SG IP V LGTW + + AV+ A+ E GY HIDTA++YG +
Sbjct: 15 SFRLLSGHKIPAVGLGTW----------RSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQR 64
Query: 91 QVGRALTKKFSEGLK----------------RESIFITTKLWN-----SYHER------E 123
+VG+ + + GL+ R+ I +++ L N ++R E
Sbjct: 65 EVGQGIKRAMHAGLERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPE 124
Query: 124 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNV-DFLD-----TWRGMIDAKKL 177
+V PAL+ +L+ L LEY+DLYLIHWPI + E + D LD WR M + K
Sbjct: 125 RVRPALQNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVWREMENLSKD 184
Query: 178 GLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPF 237
L ++IG+ NF ++ +++ P+ Q+E++ + + +FC++N+I V AY+P
Sbjct: 185 SLVRNIGVCNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYSPL 244
Query: 238 GSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQ 297
GS + I D+ + IA+K NKT Q+ +++ ++ G V+PKS++ ERI++
Sbjct: 245 GS-------QEGGRDLIHDQTVDRIAKKLNKTPGQILVKWGLQRGTSVIPKSLNPERIKE 297
Query: 298 NIQLFDFSLTPEEFNLLKSFDTGYRTL 324
NI++FD+ + ++F L S R +
Sbjct: 298 NIKVFDWVIPEQDFQALNSITDQKRVI 324
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 144 bits (350), Expect = 2e-33
Identities = 96/284 (33%), Positives = 153/284 (53%), Gaps = 30/284 (10%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L++G IP + LGTW R VV E AV A + GY HIDTA YG E VG
Sbjct: 17 LNNGNKIPKLGLGTW---RIDDNVV------EAAVREAFKVGYRHIDTAQAYGNERGVGE 67
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI---A 151
A+ K +KRE +FIT+K+ Y + + ++ SL+ + L+++DL LIH P +
Sbjct: 68 AVRKS---KIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNS 124
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
+ D +NV+ + + DA+K G +SIG+SNF Q+ ++ I+ + KP+A QI
Sbjct: 125 FRKGDYFKENVE---VYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQILC 181
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
++ L +C++ +I+ AY+P A + D R++ +A+KYN +
Sbjct: 182 HIGNTPFTLLDYCKKQNILAEAYSPI-----------AHGELLKDPRVIELAKKYNVSPA 230
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLK 315
Q+ +R+ +ELG V LPKS + I +N Q+ DF+ + + LK
Sbjct: 231 QICIRYTLELGLVSLPKSKTPKYIAENAQV-DFTFSKADLQTLK 273
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 144 bits (349), Expect = 3e-33
Identities = 116/337 (34%), Positives = 171/337 (50%), Gaps = 51/337 (15%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
++P++ L++G +PV+ LGTW GK V T +AV A+ AGY HIDTAY Y
Sbjct: 1 MIPSVTLNTGALMPVLGLGTW----KSGKGV-----TTEAVKVAIGAGYRHIDTAYVYEN 51
Query: 89 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E +VG + +G+ KRE +FI +KLW ++H V A K+L +LNL+YVDLYL+H
Sbjct: 52 ETEVGAGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMH 111
Query: 148 WPI----AMFENDTLLDNV-----DFLDTWRGMIDAKKLGLTKSI---GISNFNQ-EQIQ 194
+P+ A + +L D + DF G D L + G S + E ++
Sbjct: 112 FPMGALSATLDLTSLTDVIPTVFRDFSPLQPGE-DPFPLDEHNQLICDGTSFLDTWEAME 170
Query: 195 RIIDSGLEKPSAL------QIELNLN------------------LQQPELFKFCRENDIV 230
++D GL K + QIE LN L Q +L FCR I
Sbjct: 171 ELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHFCRSRGIS 230
Query: 231 VMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSV 290
V A+ GS S A D P +DD ++ +IA+K T QV ++F I+ + KSV
Sbjct: 231 VTAFACLGSADRSWASAD-EPSFLDDPQINAIARKNQMTPAQVLIKFQIQRNITAVVKSV 289
Query: 291 HKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR--TLP 325
RI++NI+ FD+ L+ ++ L SF++ +R TLP
Sbjct: 290 SPHRIKENIKAFDYELSDDDMKTLMSFNSNWRGYTLP 326
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 144 bits (348), Expect = 4e-33
Identities = 90/278 (32%), Positives = 138/278 (49%), Gaps = 21/278 (7%)
Query: 66 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF---SEGLKRESIFITTKLWNSYHER 122
+ AV AL GY HID AY Y E+ +GRA K F S G+KRE ++IT+KLWN H
Sbjct: 20 QTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYNHRP 79
Query: 123 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND------------TLLDNVDFLDTWRG 170
E V +K++ +L ++Y+DL+L+HWP+A ND +L+ V DTWR
Sbjct: 80 ELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADTWRA 139
Query: 171 MIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIV 230
M + GL K IG+SN+ + +++ KP QIE++ KFC +N I
Sbjct: 140 MEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDNGIG 199
Query: 231 VMAYTPFGSLFPSKAQPDAPPPRI--DDERLVSIAQKYNKTVPQVALRFLIELGAV---- 284
V AY+P G + P + + + L +IA + VAL + ++
Sbjct: 200 VTAYSPMGGSYADPRDPSGTQKNVILECKTLKAIADAKGTSPHCVALAWHVKKWNTSMYS 259
Query: 285 VLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
V+PKS RIE N + + L+ ++ + + + R
Sbjct: 260 VIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKR 297
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 143 bits (347), Expect = 5e-33
Identities = 88/286 (30%), Positives = 148/286 (51%), Gaps = 35/286 (12%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
+ G +P + LG W P + +V + A++ GY +DTA Y E+ V
Sbjct: 14 ISFHDGHTMPQIGLGVW--ETPPDETAEVVKE-------AVKLGYRSVDTARLYKNEEGV 64
Query: 93 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
G+ L IF+TTKLWN + + A +S L +DLYLIHWP+
Sbjct: 65 GKGLED-------HPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMPA 117
Query: 153 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 212
+++TW+ +++ KK G KSIG+SNF E ++RI+D+ P QIEL+
Sbjct: 118 --------QGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELH 169
Query: 213 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQ 272
+ QQ L +F +++I ++ P G K + + DER+ IA+K+++T Q
Sbjct: 170 PDFQQRALREFHEKHNIRTESWRPLG-----KGRV------LSDERIGKIAEKHSRTPAQ 218
Query: 273 VALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
V +R+ ++ G +V+PKSV+ +R+ +N+ +F F L ++ ++ D
Sbjct: 219 VVIRWHLQNGLIVIPKSVNPKRLAENLDVFGFVLDADDMQAIEQMD 264
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 143 bits (347), Expect = 5e-33
Identities = 88/285 (30%), Positives = 140/285 (49%), Gaps = 22/285 (7%)
Query: 30 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
+P L+SG +P + +GT+ H G+V +V A E GY H D A Y
Sbjct: 16 IPQRTLASGARMPAIGMGTFGSDHAAPGEVAA-------SVYAAAELGYRHFDCAAVYSN 68
Query: 89 EDQVGRALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 146
E ++G + + G++RE ++IT+KLWN H VIPA KSL +L L+Y+DLYLI
Sbjct: 69 EREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLI 128
Query: 147 HWPIAMFE------NDTLLD-----NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQR 195
HWP F + D + +F+ TWR + GL + IG SN ++Q
Sbjct: 129 HWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQL 188
Query: 196 IIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL-FPSKAQPDAPPPRI 254
++ +P+ ++EL+ + QQP LF + R +IV + Y P GS P + + +
Sbjct: 189 LLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCPLGSPGRPERDRTAEDTSPL 248
Query: 255 DDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNI 299
+D + IA + V L++ ++ G +P S + I N+
Sbjct: 249 EDPVIQRIAAAHGMHPAAVCLKWAVQRGQTPIPFSTKRRNIHANL 293
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 143 bits (347), Expect = 5e-33
Identities = 96/288 (33%), Positives = 148/288 (51%), Gaps = 35/288 (12%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
PTL L+ G IP + GTW D QAV A++ GY IDTA YG E
Sbjct: 5 PTLNLNDGRQIPQLGFGTWQMEE---------EDAPQAVSTAIDVGYWLIDTAAIYGNEK 55
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VG+ + + +S+ IF+ TK+WN ++ + A K LE L E+VD+ LIHWP
Sbjct: 56 GVGKGVGE-WSD------IFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPC 108
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
E D F+DTW+ +I+ + G KSIG+SNF +E ++RIID P+ QIE
Sbjct: 109 P--EKD------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIE 160
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTV 270
L+ + QQ ++ K + IV +++P G K + +E + +IA++ +
Sbjct: 161 LHPSFQQRDMRKVHEDLGIVTQSWSPLGQ---GKG--------MSNEVIEAIAEETGQPE 209
Query: 271 PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
V LR+ I+ G +PK+ ++ IE N + F L+ E+ + + D
Sbjct: 210 TAVILRWHIQHGLCPIPKASSRDHIEANFKALSFELSDEQMGRIDALD 257
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 143 bits (347), Expect = 5e-33
Identities = 97/303 (32%), Positives = 155/303 (51%), Gaps = 33/303 (10%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYTHIDTAYKYGIED 90
T L++ IP V GT+L ++ND ++ I A ++AGY HIDTA Y E
Sbjct: 39 TFTLNTTTTIPAVGFGTYL----------ISNDDAKSTISAAIQAGYRHIDTASGYQNEK 88
Query: 91 QVGRALTKKF-SEGLKRESIFITTKLW-------NSYHEREQVIPALRKSLENLNLEYVD 142
VG + S G+ R+ +F+T KLW ++ + Q + SL L L+YVD
Sbjct: 89 TVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVD 148
Query: 143 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
LYLIH P + D L+ WR +++ + G +SIG+SNFN+ + I +GL
Sbjct: 149 LYLIHAP---YGGDMRLEQ------WRALLELQANGKARSIGVSNFNESHLNEIKAAGLP 199
Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLV-- 260
P A QIEL+ Q+P+L + ++ I +AY+ L + + + D+ +
Sbjct: 200 MPDANQIELHPWSQKPDLLAYMDQHAIAPIAYSSLVPLSTWRTKEGQASAKTDEMKAAGT 259
Query: 261 ---SIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSF 317
+A+KY + Q+ LR+ ++ G VLPKS++ +R+ QNI LF FS+ + + +
Sbjct: 260 TFRDMAEKYGVSEAQLLLRWGVQNGYAVLPKSMNPDRMRQNIDLFSFSIDDTDMAKMATM 319
Query: 318 DTG 320
D G
Sbjct: 320 DQG 322
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 143 bits (346), Expect = 7e-33
Identities = 100/298 (33%), Positives = 152/298 (51%), Gaps = 30/298 (10%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
TL L++G +P++ LGT+ GK Q +A+ A+E GY D+A Y E +
Sbjct: 3 TLTLNNGVKMPILGLGTY---SLTGKAGQ------KAMSEAIEVGYRLFDSAQMYNNEAE 53
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
+G A+ G+KRE FI TKL S E + ++ KSL+ L L+Y+D LIH P +
Sbjct: 54 LGAAINAAVKGGIKREEFFIQTKLLESSSE-DLAKKSIEKSLKTLGLDYIDSLLIHMPYS 112
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
+ +R M K G+ + IGISNF + + S P+ Q E
Sbjct: 113 QSKA-----------MYRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCET 161
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
+L LQQ L + + ++ +++PF K +++ L SIAQKYNKT
Sbjct: 162 HLLLQQKPLREAMKSKKTLLQSWSPF---IAGKGSI------LENPTLKSIAQKYNKTPA 212
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKW 329
QV LRFLIE G V+PK+ + R+++N+ +FDFSL+ ++ +LK DT T +
Sbjct: 213 QVVLRFLIEQGISVIPKTSKRARMQENLNVFDFSLSAQDTQILKELDTNKSAFSWTNY 270
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 143 bits (346), Expect = 7e-33
Identities = 93/284 (32%), Positives = 148/284 (52%), Gaps = 30/284 (10%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
PT++LS G +P++ +GTW KG+ + AV A+E GY +DTA YG E+
Sbjct: 9 PTVELSGGTRMPMLGMGTW---PLKGE------ECRAAVASAIEQGYRLVDTAEAYGNEE 59
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VG+A+ + G R IF+TTK +H R+ V AL SLE L L+YVDL+L+HWP+
Sbjct: 60 AVGKAVREA---GPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM 116
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
++D +RGM++ K+ GL K+IG+SNF + +I G+ P QI+
Sbjct: 117 P--------GEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEGM-TPEVNQIQ 167
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTV 270
L+ + + E+ F +DIV A++P G + +AP ++ A+K+ T
Sbjct: 168 LDPSRPRLEVRDFLDNHDIVTEAWSPLGR--GADGVLNAP-------AVLDAAKKHGITP 218
Query: 271 PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
L + + G V +PKS + E N++ L+ +E +
Sbjct: 219 AAAVLAWELNQGIVTIPKSANPEHQRTNLEAIGVELSAQEMKAI 262
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 143 bits (346), Expect = 7e-33
Identities = 87/257 (33%), Positives = 144/257 (56%), Gaps = 21/257 (8%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+P LSSG +P V +GT P G T + V+ A+EAGY H DTA Y E
Sbjct: 1 MPEAALSSGKPMPRVGMGT--ASFPLGATDPST--VKDVVLRAIEAGYRHFDTAAVYQTE 56
Query: 90 DQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
+G A+ + GL R+ ++IT+KLW ++ V+P+LR++L + +EY+DLYLIH
Sbjct: 57 AILGDAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIH 116
Query: 148 WPIAM----------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 197
+P++M + D L+ +D W+ M + ++LGLTK+IG+SNF+ ++++ ++
Sbjct: 117 FPVSMRLAEDPESMTYSKDDLV-MMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLL 175
Query: 198 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDE 257
P+A Q+E++ +Q +L +FC+E I + AY+P G K P + +D
Sbjct: 176 SFATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSPLG----GKGTPWSNNAVMDCP 231
Query: 258 RLVSIAQKYNKTVPQVA 274
L IA + KT+ Q++
Sbjct: 232 LLKQIAMERGKTIAQIS 248
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 143 bits (346), Expect = 7e-33
Identities = 101/297 (34%), Positives = 161/297 (54%), Gaps = 31/297 (10%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T +L++G +IP+ GT+ H + + QV + YALEAGY HIDTA Y E+
Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQE-LIYQVLD-------YALEAGYRHIDTAVVYRNEEY 84
Query: 92 VGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPAL-RKSLENLNLEYVDLYLIHWP 149
+G AL + LKRE IFIT+KL + + E + + RKSL NL +Y+DLYLIHWP
Sbjct: 85 IGTALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWP 144
Query: 150 IA---------MFEND-TLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII- 197
+F T DNV + +W + ++ G +SIG+SN+ + ++ ++
Sbjct: 145 GVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLA 204
Query: 198 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDE 257
D P+ Q+E + QPEL ++CR++ I + AY+ GS ++ + +DE
Sbjct: 205 DCKGIVPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYSSLGSSNTAELR--------EDE 256
Query: 258 RLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
+ S+A+ KT QV LR+ IE +LPK+ ++ I++N+ L +F + E+ L
Sbjct: 257 TVQSVAKSLQKTPVQVLLRWAIEQEVGILPKARSRDHIQENVGL-EFEIPAEQMKQL 312
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 143 bits (346), Expect = 7e-33
Identities = 87/285 (30%), Positives = 148/285 (51%), Gaps = 16/285 (5%)
Query: 40 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 99
N+P++ +GTW VQ Q + + GY IDTA Y E ++GR L K
Sbjct: 10 NMPLIGIGTWQ--------VQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKL 61
Query: 100 F-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL 158
+ GLKRE I+IT+KL S ++ ++ +SL NL +EY+DL LIHWP + +++
Sbjct: 62 LPANGLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENP 121
Query: 159 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQP 218
+ +++W M + G +S+G+SNF ++ + P+ Q+E + + Q
Sbjct: 122 ANKKLRVESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQD 181
Query: 219 ELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFL 278
+L K+C EN+I AY+ GS P+ + + P I + +AQKYN +P + L F
Sbjct: 182 DLVKYCNENNIHFQAYSSLGS--PTYRKQLSEEPLIKE-----LAQKYNVEIPVLLLGFA 234
Query: 279 IELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRT 323
G VLP++ + E + N ++ ++T E+ + L + ++T
Sbjct: 235 YCQGISVLPRTTNPEHVATNFKVTKLAITQEDIDRLLALTVEHKT 279
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 142 bits (345), Expect = 9e-33
Identities = 98/320 (30%), Positives = 179/320 (55%), Gaps = 33/320 (10%)
Query: 23 PQSAELIVPT---LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTH 79
P+ + PT L+L++G ++P+V +GT+ + +G+ V ++ + + G+
Sbjct: 13 PELEAALTPTIRDLRLNNGYDMPLVGIGTY---KVRGREV-----IKRVIDESFAVGFRS 64
Query: 80 IDTAYKYGIEDQVGRALTKKFSE-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLN 137
IDTA Y E+ +G AL + + LKRE IFIT+KL S + + +++ ++ SL+ L+
Sbjct: 65 IDTAVVYRNEEDIGLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALD 124
Query: 138 LEYVDLYLIHWPIAMFENDTLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 196
Y+DLYLIHWP A + DN + TW +++ ++ GL +SIG+SN+ ++ +
Sbjct: 125 TSYLDLYLIHWPGASRILENSPDNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHL 184
Query: 197 ID--SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRI 254
++ SG+ KP Q+E + + +Q EL +FC + I V AY+ G+ + +
Sbjct: 185 LEHCSGV-KPDVNQVECHPHFRQDELIEFCTKQGIHVQAYSSLGTSDTTNL--------L 235
Query: 255 DDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
+D + IA + N + +V L++ ++ G ++PK++ + I+ NI+L DF ++ ++ LL
Sbjct: 236 EDPVVKKIASELNVSPARVLLKWALQRGLGIIPKAIKSDHIKDNIKL-DFEISKDQMTLL 294
Query: 315 KSFDTGYRTLPQTKWSKHPD 334
S LPQ K+S +PD
Sbjct: 295 LS-------LPQQKYSWNPD 307
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 142 bits (345), Expect = 9e-33
Identities = 96/301 (31%), Positives = 151/301 (50%), Gaps = 24/301 (7%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P + L++G +P + LG + +T A+ A+ +GY IDTA Y E
Sbjct: 6 PLINLNNGVKMPALGLGVFAAS---------AEETASAIASAISSGYRLIDTARSYNNEA 56
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
QVG + + G+ R +F+TTKL+N + E+ + A +SL L L+YVDLYL+HWP
Sbjct: 57 QVGEGIR---NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWPT 113
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
+ N T+ +W+ G ++IG+ NF ++Q+ +I + P+ QIE
Sbjct: 114 KDW-NATI-------QSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQIE 165
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPR---IDDERLVSIAQKYN 267
L+ Q L R IV A++P G + D R + D + +IA+ +
Sbjct: 166 LHPYFAQKPLLAKNRALGIVTEAWSPIGGAI-NDGDGDNHGGRKHPLTDPVITTIAEAHG 224
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQT 327
++ QV LR+ + V +PKSV+ ERI +NI +FDF+L+ E L DTG R P
Sbjct: 225 RSAAQVILRWHFQNDVVAIPKSVNPERIAKNIDVFDFALSDAEMAQLDELDTGVRIGPDP 284
Query: 328 K 328
+
Sbjct: 285 R 285
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 142 bits (344), Expect = 1e-32
Identities = 82/256 (32%), Positives = 148/256 (57%), Gaps = 20/256 (7%)
Query: 64 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 123
D + + AL+AG+ H DTA Y ED VGRAL +++E + RE +FIT+K+
Sbjct: 28 DVDSLIRQALKAGFRHFDTAQAYFNEDGVGRAL--RYTE-VPREQLFITSKIRGRDMGYA 84
Query: 124 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 183
+ + + ++LE L +EY++L+LIHWPI N+ +++TW I+ + GL +SI
Sbjct: 85 RTLVSFNETLERLGVEYLELFLIHWPIPA-------KNL-YVETWEASIELEASGLIRSI 136
Query: 184 GISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPS 243
G+SNF + I+R+I+ P+ Q+EL+ + QQ ++ + E I + +Y+PFGS +
Sbjct: 137 GVSNFTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYSPFGSNGAA 196
Query: 244 KAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFD 303
+ + ++ +A++++ + Q+ LR+ ++ G LP++ + R +N+ ++D
Sbjct: 197 VLR---------NAVVMVLARRHDHSPAQIVLRWHLQQGLTPLPRTTNGARFSENVDVWD 247
Query: 304 FSLTPEEFNLLKSFDT 319
F L+ EE LL S +T
Sbjct: 248 FELSEEEMKLLASLNT 263
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 142 bits (344), Expect = 1e-32
Identities = 92/274 (33%), Positives = 142/274 (51%), Gaps = 33/274 (12%)
Query: 64 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL--------------TKKFSEGLKRESI 109
D V ALEAGY H DTA YG E VG+A+ + + + L RE +
Sbjct: 29 DAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGALAGFAGGGPAGGSGEAAPSLSREDL 88
Query: 110 FITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWR 169
F+TTK+WN H + + A S+ NL +EYVDLYLIHWP A F +++R
Sbjct: 89 FVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCAR--------RGLFTESYR 140
Query: 170 GMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDI 229
M + G ++IG+SNF ++ ++++ P+ QIEL+ LQQ EL + I
Sbjct: 141 AMETLYREGRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGI 200
Query: 230 VVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKS 289
A++P G + Q A P ++ +A + ++ Q+ LR+ ++LG VV+PK+
Sbjct: 201 RTEAWSPLG-----RGQVLADPV------VLELAAAHRRSAAQIILRWHVQLGNVVIPKA 249
Query: 290 VHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRT 323
RI +N+ +F F+L P E L + + G+RT
Sbjct: 250 SSYARIRENLDVFGFTLDPAEMAALAALERGHRT 283
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 142 bits (344), Expect = 1e-32
Identities = 112/333 (33%), Positives = 175/333 (52%), Gaps = 50/333 (15%)
Query: 14 ERDLYEFLIPQSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL 73
E + L P++ E+ L++G IP + LGT P K+ + T+QAV A+
Sbjct: 9 ENIVENMLHPKTTEIY---FSLNNGVRIPALGLGT---ANPHEKLAE----TKQAVKAAI 58
Query: 74 EAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKS 132
+AGY HIDTA+ Y E VG A+ + +G +KRE +FITTK+W ++V +L +S
Sbjct: 59 KAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNES 116
Query: 133 LENLNLEYVDLYLIHWPIAMFEN-----------DTLLDNV---------DFLDTWRGM- 171
L+ L LEYVDL L HWP+ FE T +D+ D+L+T++ +
Sbjct: 117 LKALGLEYVDLLLQHWPLC-FEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLE 175
Query: 172 ---IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCREND 228
+D ++IG+SNF+ E ++R+I KP+ Q+E + +L Q EL KFC +D
Sbjct: 176 KIYLDPND-HRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHD 234
Query: 229 IVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPK 288
I++ AY+P G S P+ P + +A+KYN T + + + I G +V+P+
Sbjct: 235 ILLTAYSPLG----SHGAPNLKIPLVK-----KLAEKYNVTGNDLLISYHIRQGTIVIPR 285
Query: 289 SVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321
S++ RI +I+ SLT +E L F Y
Sbjct: 286 SLNPVRISSSIEF--ASLTKDELQELNDFGEKY 316
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 142 bits (343), Expect = 2e-32
Identities = 95/291 (32%), Positives = 147/291 (50%), Gaps = 35/291 (12%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE--QAVIYALEAGYTHIDTAYKYG 87
+P ++L+ G IP + G V Q++N E +AV A+ GY IDTA Y
Sbjct: 4 IPKIKLNDGNEIPQLGFG----------VFQISNHDEAVKAVESAISNGYRLIDTAEAYN 53
Query: 88 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
+ VG A+ + + R+ IF+TTKLW S E+ A+ + L+ L +Y+D+ L+H
Sbjct: 54 NQTAVGEAIK---NSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH 110
Query: 148 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 207
D WR + DA+K G TKSIG+SNF +Q+ + KP
Sbjct: 111 QAYG-----------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVN 159
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
QIE+N Q+ K+ +++D+ V A+ PF + + L I +KY
Sbjct: 160 QIEVNPWFQREPEVKWNQKDDVAVEAWAPFA---------EGKDGIFTNPVLTEIGKKYG 210
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
K+ QV LR+LI+ G +V+PKSVH R ++NI +FDF L ++ + + D
Sbjct: 211 KSNGQVILRWLIQRGIIVIPKSVHDARQKENIDIFDFELNNDDMQKIAALD 261
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 141 bits (342), Expect = 2e-32
Identities = 85/264 (32%), Positives = 141/264 (53%), Gaps = 13/264 (4%)
Query: 63 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 122
++T AV AL GY HIDTA YG E +VG + + G+ R+ +FI TK+W S +
Sbjct: 42 DETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRA---GIARDEVFIETKIWISDYGY 98
Query: 123 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 182
++ + A KS L ++ +DL L+H P+ + TL +R + G ++
Sbjct: 99 DETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRTL-------GAYRALEKLLADGKVRA 151
Query: 183 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFP 242
IG+SNF E + R++ P+ QIE++ QQ L + E+ I+ A++P G +
Sbjct: 152 IGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRLHAEHGILTQAWSPIGGITF 211
Query: 243 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLF 302
+ + ++D L+ IAQ++ K+ QV LR+ ++ G V+PKS RI +N +F
Sbjct: 212 YRGGEKST---LEDPVLLEIAQQHGKSAAQVMLRWHLQEGRSVIPKSTKPARIAENFDVF 268
Query: 303 DFSLTPEEFNLLKSFDTGYRTLPQ 326
DF L+ E+ + + DTG R+ P+
Sbjct: 269 DFELSGEQIAAIDALDTGVRSGPE 292
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 141 bits (342), Expect = 2e-32
Identities = 92/290 (31%), Positives = 148/290 (51%), Gaps = 19/290 (6%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P ++L+ +IP++ GT + V + +A+ A+ GY H+D A YG E
Sbjct: 10 PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
++G A+ + G+ RE +F+TTK+ + + + A+ +SL L L YVDLYLIH P
Sbjct: 70 ELGVAIKES---GIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLIHSPF 123
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
++D L W M ++ G K+IG+SN++Q ++ + + + P QIE
Sbjct: 124 -FAKSDGELQQA-----WAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIE 177
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTV 270
+ LQQ EL +F RE DI + +Y G L P P P D ++ +A KY T
Sbjct: 178 HHPYLQQEELLRFQREKDIKIASY---GPLTPILRAPGGPV----DPKVSELAAKYKVTE 230
Query: 271 PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
+V LR+ I+ G V + S + R+++ +Q+ F LTPEE + G
Sbjct: 231 GEVLLRWSIDRGDVAVTTSSKESRLQEFLQVLTFQLTPEEVREISQLGQG 280
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 141 bits (341), Expect = 3e-32
Identities = 94/290 (32%), Positives = 162/290 (55%), Gaps = 39/290 (13%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIEDQ 91
++L++G ++P++ LG + + +G+ + E +I A++ GY IDTA Y E+
Sbjct: 4 IKLANGLHMPIIGLGVY---KAEGE------NCENTIIKAIDDYGYRMIDTAQVYFNEEF 54
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VG A+ + +KRE IFITTK+W S + + ++ KSL+ L Y+DL L+H P
Sbjct: 55 VGNAIKQT---KIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG 111
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE---KPSALQ 208
D+ W+ + K G+ K+IG+SNF + R++D L KP Q
Sbjct: 112 -----------DYYSAWKALEVLYKKGIVKAIGVSNFEAD---RLVDFCLHVDVKPVINQ 157
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
IEL+ Q+ E + + + V ++ FG A +++ LVS+A+KYNK
Sbjct: 158 IELHPLRQRIEDLHWNNKYGVAVESWASFGR---------ATSEIMENPILVSLAEKYNK 208
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
TVPQ+ LR+LI+ VV+PK+V + R+++N+ +FDF ++ ++ +L+K+ +
Sbjct: 209 TVPQIILRWLIQQNIVVIPKTVTESRLKENMDIFDFEISDDDMDLIKTIN 258
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 141 bits (341), Expect = 3e-32
Identities = 97/302 (32%), Positives = 155/302 (51%), Gaps = 16/302 (5%)
Query: 35 LSSGGNIPVVAL-GTWLG-HRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIEDQ 91
L++G IP +A+ GT ++ + +N + ++YAL+ G HID A Y +
Sbjct: 10 LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VG+AL+ +E R +IF+T K + L +L+ + +YVDLYL+H P
Sbjct: 70 VGKALS--LTEK-PRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPFV 126
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
E ++ + + W+ M K G K+IG+SNF E +QRI+ KP QIE
Sbjct: 127 SKE----VNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIEF 182
Query: 212 N--LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
+ L Q P ++KFC+E+DI+V AY+P G L AQ D+ P E + +++KY K+
Sbjct: 183 SPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQDDSQP---FFEYVKELSEKYIKS 239
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKW 329
Q+ LR++ + G + + S +RI LF F LT EE + + + L + W
Sbjct: 240 EAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSFDLTAEEVDKITELGLEHEPL-RLYW 298
Query: 330 SK 331
+K
Sbjct: 299 NK 300
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 140 bits (340), Expect = 4e-32
Identities = 100/297 (33%), Positives = 153/297 (51%), Gaps = 27/297 (9%)
Query: 23 PQSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQ-VTNDTEQAVIYALEAGYTHID 81
P+ ++P+L+LS G IP++ G + G ++ A + AL AGY H+D
Sbjct: 17 PKQIHNLIPSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLD 76
Query: 82 TAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
A YG E ++GRA+ + L R S++ITTK + V + +SLE L L+YV
Sbjct: 77 GAEVYGNEVELGRAIAQ---SKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYV 131
Query: 142 DLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--S 199
DLYL+H P +N L WR M K G+ KSIG+SNF +Q + D
Sbjct: 132 DLYLLHSPF-FAKNPEQLQ-----AAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPG 185
Query: 200 GLEKPSAL-QIELNLNLQQ----PELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRI 254
GL+ P + QIE + LQ +L FCRE I + AY+P ++ +KA+P P
Sbjct: 186 GLQYPPVVNQIEYHPYLQHVVEGEDLVAFCREKHIAIAAYSPLTAI--TKARPGPVDP-- 241
Query: 255 DDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNI-QLFDFSLTPEE 310
+A+KY + ++A R+ ++ G V L S ++ER++ + +L F LTP+E
Sbjct: 242 ---IYTQLAKKYGVSEAEIAFRWCLDQGIVTLTTSSNEERLKGYLKKLPSFKLTPKE 295
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 140 bits (340), Expect = 4e-32
Identities = 96/298 (32%), Positives = 153/298 (51%), Gaps = 38/298 (12%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+P+ L++G +P V +G W G G+ N+ A++ A++ GY H+DTA Y E
Sbjct: 5 IPSFTLNTGAKLPSVGMGCWQGQPGPGR----DNELVDALVRAIKVGYRHLDTATGYRNE 60
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
+VG+A+ + G+ R IF+TTKL H+ V+ L SL L ++Y+DL+L+HW
Sbjct: 61 AEVGQAVRQS---GVARSEIFVTTKLRPGGVHD---VVQELENSLNELGIDYIDLWLLHW 114
Query: 149 PIAMFENDTLLDNVD-------------FLDTWRGMIDA---KKLGLTKSIGISNFNQEQ 192
P ++D + F +TW M D G K+IG+SNF+ +
Sbjct: 115 PQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIKN 174
Query: 193 IQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPP 252
++ + + P+ QIE + L + EL K+C+ I V AY+P G S
Sbjct: 175 LEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSPLGQYNASIH------- 227
Query: 253 RIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
+D+ L IA+K++ T VAL + ++ G V PKS +++R++QNI L LT EE
Sbjct: 228 --EDKDLNEIAKKHDVTAATVALSWAVQRGTSVAPKSTNEKRMKQNITL--IKLTDEE 281
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 140 bits (339), Expect = 5e-32
Identities = 94/291 (32%), Positives = 149/291 (51%), Gaps = 35/291 (12%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN--DTEQAVIYALEAGYTHIDTAYKYGIE 89
T++L++G +P++ GT+ Q+T+ + E AV A++AGY HIDTA Y E
Sbjct: 3 TVKLNNGVEVPILGFGTY----------QITDAAEAEHAVKDAIKAGYRHIDTAQSYMNE 52
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+ VGR + + G+ R+ +FITTK+W + V+ + +SL+ L L+YVDL LIH P
Sbjct: 53 EAVGRGIA---ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP 109
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
D W M + + G ++IG+SNF+ +++ + P QI
Sbjct: 110 FN-----------DVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQI 158
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
E+N QQ R+ + + A+ PF ++ + D ++ L I KY K+
Sbjct: 159 EVNPFQQQTANLAILRKEGVAIEAWAPF-----AEGKNDI----FNNPVLTKIGAKYGKS 209
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
QV LR+L+E +VL KSV ER+ QN+ +FDF LT + + D G
Sbjct: 210 AAQVILRWLVEQDIIVLAKSVKPERMAQNLAIFDFELTEADKEEIAGLDQG 260
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 140 bits (339), Expect = 5e-32
Identities = 88/291 (30%), Positives = 151/291 (51%), Gaps = 30/291 (10%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+PT+ L+ G LGT+ +G A++ A+++GY +DTA Y E
Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVA---------AMVAAIDSGYRLLDTAVNYENE 54
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+VGRA+ + + R+ + + +K+ H R + + ++R SL+ L L+ +DL LIHWP
Sbjct: 55 SEVGRAVR---ASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP 111
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
N ++ +LDTWRGMIDA++ GL +SIG+SNF + ++ +ID P+ Q+
Sbjct: 112 -----NPSV---GRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQV 163
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
EL+ Q L F E+ I +++P + ++ L +A Y T
Sbjct: 164 ELHPYFPQAALRAFHDEHGIRTESWSPLA----------RRSELLTEQLLQELAVVYGVT 213
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
QV LR+ ++LG+ +PKS +R +N +F F+LT ++ + + + G
Sbjct: 214 PTQVVLRWHVQLGSTPIPKSADPDRQRENADVFGFALTADQVDAISGLERG 264
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 139 bits (337), Expect = 8e-32
Identities = 88/291 (30%), Positives = 152/291 (52%), Gaps = 30/291 (10%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+P L+L G IP + LGTW + ++ E AV +AL++GY +DTA++Y E
Sbjct: 13 IPRLKLPHGHTIPRLGLGTW---------PMLEDECETAVRFALQSGYRLVDTAFQYRNE 63
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+ VGR + + G+ R +FI++K H + V A +SL L L+++D+++ HWP
Sbjct: 64 EAVGRGIR---TAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWP 120
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
+ ++D W+G++ + G K+IG+SNF ++ IID+ P QI
Sbjct: 121 VPALGK--------YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQI 172
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
+L+ +L + E R IV A++P G +A P ++ IAQ+ +K+
Sbjct: 173 QLSPDLARTEPRAVHRLLGIVTEAWSPIGRSSGLRANP----------LIIEIAQRLDKS 222
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
QV LR+ ++ V +P++ +++N+ +FDFSLT E ++ D G
Sbjct: 223 PAQVLLRWHVQQDIVPIPQASDPLWLKENLSVFDFSLTAGEMASIRKLDRG 273
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 139 bits (336), Expect = 1e-31
Identities = 94/280 (33%), Positives = 142/280 (50%), Gaps = 33/280 (11%)
Query: 38 GGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 96
G ++P + LGTW Q+T + + V AL GY HIDTA YG E QVG +
Sbjct: 8 GTSVPALGLGTW----------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGM 57
Query: 97 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 156
+ + RE +F+TTKL S + V + R+SL L +Y+DL LIHWP N
Sbjct: 58 D---AAAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP-----NT 109
Query: 157 TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQ 216
+ ++ +T M D + GL + IG+SNF+ + R D Q++ +
Sbjct: 110 PWMASLS--ETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWD 167
Query: 217 QPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALR 276
Q +L +CR +D+++ AY+P A +DD LV I KY K+ QVALR
Sbjct: 168 QRKLLDYCRIHDVLLTAYSPL-----------ARGGVLDDPALVQIGNKYGKSPAQVALR 216
Query: 277 FLIEL-GAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLK 315
+L++ G +PK+ +E +E N+ +FDF LT E ++
Sbjct: 217 WLVQQDGVAAIPKASSREHLEANLAVFDFELTDAEMERIR 256
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 138 bits (335), Expect = 1e-31
Identities = 97/297 (32%), Positives = 148/297 (49%), Gaps = 22/297 (7%)
Query: 28 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 87
+IVP+++L SG +P++ LGT+ +Q +Q+V AL+AGY DTA YG
Sbjct: 1 MIVPSVRLMSGTQMPLLGLGTYK--------LQDHEQLKQSVSCALQAGYRAFDTAAVYG 52
Query: 88 IEDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 146
E +G+ L + + GL RE +FI +KL S H LR SLE L+ EY+DLYLI
Sbjct: 53 NEAHLGQVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLI 111
Query: 147 HWP-IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 205
HWP + + + + +W + + G K+IG+SN+ + I+ ++ S P+
Sbjct: 112 HWPGMEGLDPEDSRHSEYRAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPA 171
Query: 206 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQK 265
LQIE L Q EL C E I AY+ G + + ++ I +
Sbjct: 172 VLQIECQPKLIQRELRDLCMETGIHFQAYSSLGK-----------GALLREPEVMDIVRH 220
Query: 266 YNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
+T QV LR+ ++ G VLP+S R+ +N Q+FDF L + L + G R
Sbjct: 221 CGRTPAQVLLRWALQQGISVLPRSSQPSRVLENAQVFDFKLNETDMKRLDDLNCGTR 277
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 138 bits (335), Expect = 1e-31
Identities = 93/288 (32%), Positives = 150/288 (52%), Gaps = 30/288 (10%)
Query: 23 PQSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDT 82
P S E +P L L G +IP + GT+ +G DT ++ AL GY +D+
Sbjct: 15 PMSIEKNIPDLILHDGHSIPALGFGTYTLKGQQGV------DT---MLRALGHGYRMLDS 65
Query: 83 AYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVD 142
A+ Y E VG A+ + GL R+ IFIT+KL +H ++ + + +SL + +Y+D
Sbjct: 66 AFNYENEGAVGAAVRQS---GLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLD 122
Query: 143 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
LYLIHWP +++ W+ +IDA+K G +SIG+SNF + I+ +
Sbjct: 123 LYLIHWPNP--------QQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGV 174
Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
P Q+EL+ Q E + I+ MA++P G +KA +DD L I
Sbjct: 175 IPVINQVELHPYFNQAEQRAYDESQQIITMAWSPLGR---AKA-------ILDDAVLKQI 224
Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
AQ+ ++TV QV LR+ +++G + +PK+ + N +FDFSL+ ++
Sbjct: 225 AQETSRTVVQVVLRWQVQMGVIPIPKAASDQNQMANQAIFDFSLSDDQ 272
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 138 bits (335), Expect = 1e-31
Identities = 95/291 (32%), Positives = 156/291 (53%), Gaps = 33/291 (11%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI----YALEAGYTHIDTAYKYGIE 89
+LS+G IP VA GT + +G ND ++ +I AL +G+ HID A YG
Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGH-----NDLDKQLIGTLELALRSGFRHIDGAEIYGTN 63
Query: 90 DQVGRALTKKFSEGLKRESIFITTKL------WNSYHEREQ-VIPALRKSLENLNLEYVD 142
++G AL + GL R+ +FIT K ++ H + Q AL+ LE+L LEYVD
Sbjct: 64 KEIGIALK---NVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVD 120
Query: 143 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
LYLIH+P ++ D ++ WR + AK GL ++IG+SNF E ++ I+D+ +
Sbjct: 121 LYLIHFPYISEKSH----GFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDANTD 176
Query: 203 K-PSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
P QIE + LQ P + ++ ++ I++ AY P G + + P P D+ L
Sbjct: 177 SIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGR-----PGPL--DKVL 229
Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
+++KY + Q+ LR++++ G + + + +ERI +++FDF L E+
Sbjct: 230 SKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELDKED 280
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 138 bits (334), Expect = 2e-31
Identities = 99/300 (33%), Positives = 152/300 (50%), Gaps = 35/300 (11%)
Query: 24 QSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDT 82
Q+ + +P L L++G IP + G V QV +T++ V ALEAGY HIDT
Sbjct: 3 QTQQNTIPQLTLNNGVKIPQLGFG----------VFQVPPEETQRIVEDALEAGYRHIDT 52
Query: 83 AYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVD 142
A Y E VG A++ + G+ RE IFITTKL N E+ A + S + L +E+VD
Sbjct: 53 AAAYRNEAGVGAAIS---ASGIPREDIFITTKLRNG--EQGNAHEAFQNSRKALGVEFVD 107
Query: 143 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
LYLIHWP+ + L + + W+ M ++IG+SNF E + ++ +
Sbjct: 108 LYLIHWPVP---SQGL-----YTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADV 159
Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
P+ Q+E++ QQ EL CRE I V AY+P G D + D +
Sbjct: 160 VPAVNQVEIHPTFQQQELAAKCRELGIAVEAYSPLGQ------GADLNATAVKD-----L 208
Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
A KY+ T Q+ L + + G +V+PKS +R+ +N+ L+P E + + + ++G R
Sbjct: 209 AGKYDATPAQIVLAWHLAQGTIVIPKSADSKRMRENLGAVAVELSPAELSEISALESGAR 268
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 138 bits (333), Expect = 3e-31
Identities = 98/296 (33%), Positives = 149/296 (50%), Gaps = 39/296 (13%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T++L+SG IP + G + + + E AV A++ GY H+DTA Y E+
Sbjct: 8 TIKLASGNLIPRLGFGVYQAR---------SKECEDAVKKAIDTGYRHVDTAQAYHNEEN 58
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSY--HEREQVIPALRKSLENLNL-----EYVDLY 144
VGRA+ + G+ R S+F+T+K S+ + +V+ +RKSL+ ++ Y+DL
Sbjct: 59 VGRAIR---NSGVPRPSVFLTSKYMPSHTVYSPTEVLDVVRKSLKKVDRCGDDKPYIDLM 115
Query: 145 LIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 204
LIH P E + W + A+K G K IG+SNF ++ + P
Sbjct: 116 LIHAPWGGEEGRK--------NNWEALTIAQKEGWVKDIGVSNFGIHHLKALPPP---VP 164
Query: 205 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQ 264
+ QIEL+ QQ ++ K+C E+ I + AY+P A D+E LV +A+
Sbjct: 165 AVNQIELHPFCQQRDIVKYCEEHGIAIEAYSPLVR---------ANKKHYDNEVLVKVAK 215
Query: 265 KYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
KY K V QV LR+ ++ G + LPKSV RIE N L+DF L E+ + D G
Sbjct: 216 KYGKEVAQVLLRWSLQKGYIPLPKSVTPSRIESNADLYDFKLDQEDMAEIDGLDKG 271
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 138 bits (333), Expect = 3e-31
Identities = 102/308 (33%), Positives = 159/308 (51%), Gaps = 32/308 (10%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T L++G IP + +GT+ Q + E+ V L+ G IDTA YG+E Q
Sbjct: 37 TYTLNTGAKIPALGVGTF----------QDPDSQEETVCQVLQRGMRLIDTARVYGVEQQ 86
Query: 92 VGRALTKKFSEGLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VGR + K G+ RE IF+ TKLW N +H + V A+ SL +L YVDL L+H+P
Sbjct: 87 VGRGIKKS---GVPREEIFLGTKLWCNDFHP-DDVERAVDDSLRDLYTPYVDLLLMHYPC 142
Query: 151 AM------FENDT----LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 200
F D + F+DTWR + K G ++IG+SNF++ +I+ ++
Sbjct: 143 TFKRGEDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRET 202
Query: 201 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL--FPSKA---QPDAPPPRID 255
P+ Q+E++ LQQ ++ RE I V+ ++P G++ F +A + A R+
Sbjct: 203 STVPAVHQMEVHPYLQQKGFNEWLREKGIHVVQFSPLGNMNDFYRQAGWSKEIAHMMRVI 262
Query: 256 DERLV-SIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
D+ ++ I QKY K+ QV L + I G V+PK+V +IE+N+ DF L E+ +
Sbjct: 263 DQPILKEIGQKYGKSPVQVVLAWGINSGRSVIPKTVIDWQIEENLAA-DFELDAEDMARI 321
Query: 315 KSFDTGYR 322
+ D R
Sbjct: 322 ATLDAKAR 329
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 136 bits (330), Expect = 6e-31
Identities = 101/297 (34%), Positives = 149/297 (50%), Gaps = 36/297 (12%)
Query: 35 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
L+SG IP + GTW G+V AV AL+AGY H+D A Y + +V
Sbjct: 9 LNSGAQIPQLGFGTW--QSAPGQV-------GDAVYEALKAGYRHLDLATIYQNQREVAE 59
Query: 95 ALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
+ + + + GLKRE IFIT+KLWNS H+ V AL + L L L+Y+DLYL+HWP++
Sbjct: 60 GIKRAYKDVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSF 119
Query: 153 FENDTLL----------------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 196
L D++ +DTW+ M K +++G+SN ++ I
Sbjct: 120 TTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAI 178
Query: 197 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL-FPSKAQPDAPPPRID 255
I++ P+ QIE + LQ EL ++C++ I V AY+ FG+ F P +
Sbjct: 179 INATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAFGNNGFGVPLLVTRPEVK-- 236
Query: 256 DERLVSIAQKYNKTV--PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
E S +++ TV QV L + G V+PKSV RI +N + + LTPEE
Sbjct: 237 -EVAESASKRLGTTVTPAQVILAWSQVGGHSVIPKSVTPSRIHENFK--EVELTPEE 290
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 136 bits (329), Expect = 8e-31
Identities = 86/277 (31%), Positives = 145/277 (52%), Gaps = 36/277 (12%)
Query: 36 SSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
++G IP + LGTW L RP +VV+ AL GY HIDTA Y E +VG
Sbjct: 6 ANGARIPAIGLGTWELSGRPCARVVE----------QALRLGYRHIDTAQVYDNEREVGD 55
Query: 95 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 154
+ + G++R+ +F+TTK+W ++ + ++++SL L L VDL L+HWP +
Sbjct: 56 GVR---ASGVRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNS--- 109
Query: 155 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLN 214
+V +T + A+++GLT+ IG+SNF I++ + E Q+E +
Sbjct: 110 ------HVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPY 163
Query: 215 LQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRID-DERLVSIAQKYNKTVPQV 273
L Q ++ C ++ + ++AY+P RI D+ L I + + KT QV
Sbjct: 164 LDQAKVRAACDQHGLALVAYSPIAR------------GRIKTDQTLAGIGRAHRKTPAQV 211
Query: 274 ALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
LR+L++ +P++ ER+ +NI++FDF L+ +E
Sbjct: 212 CLRWLVQQNVAAIPRTSRIERLSENIEIFDFELSDDE 248
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 135 bits (327), Expect = 1e-30
Identities = 87/259 (33%), Positives = 138/259 (53%), Gaps = 23/259 (8%)
Query: 66 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQV 125
+Q V LE GY +DTA YG E VG A+ K S + RE IFIT+K+W + +
Sbjct: 30 QQVVEDGLEVGYRLVDTAQIYGNEQAVGDAI--KHSN-VPREDIFITSKIWVDDYGYDNT 86
Query: 126 IPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGI 185
+ A S++ L L+Y+DLYLIH P D+ TWR + + G ++IG+
Sbjct: 87 LKAFDDSMKKLQLDYIDLYLIHKPYN-----------DYYGTWRALERLYQEGRIRAIGV 135
Query: 186 SNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKA 245
S+F E++ +I KP+ QIE N+ Q+ + ++ + + A+ PF A
Sbjct: 136 SSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQQYMEKEGVQPEAWAPFAE----GA 191
Query: 246 QPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFS 305
P +++ IA+K++KT QV LR+ ++ VV+PKSVHK+R+ +N +FDF
Sbjct: 192 NHIFTNPLLEE-----IAEKHHKTTAQVMLRWFLQRNYVVIPKSVHKKRLAENYDVFDFE 246
Query: 306 LTPEEFNLLKSFDTGYRTL 324
L ++ +K+ D G+ L
Sbjct: 247 LDADDMKKIKTLDQGHSIL 265
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 135 bits (327), Expect = 1e-30
Identities = 93/300 (31%), Positives = 157/300 (52%), Gaps = 23/300 (7%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQV 92
+L+SG NIP V GT+ +VT + A+ AL AGY DTA Y E ++
Sbjct: 14 KLNSGYNIPFVGFGTY----------KVTGENVPPAIDAALTAGYRMFDTAKYYLNEKEL 63
Query: 93 GRALTKKFSE-GLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
G AL + GL R +F+T+K + S + RE + +SL++L +Y+D+YL+H+P
Sbjct: 64 GEALKILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPK 123
Query: 151 AMFENDTLLDNVDFLD-TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
++ ++N ++ + + +AK G +SIG+SN+ ++ + P A Q+
Sbjct: 124 PNDSDNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQL 183
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
E + + + L K+C+E +I A F S A+ + P I+D +V +A+K+N +
Sbjct: 184 EYHPHFARIPLQKYCKEKNIFFQA-------FSSLARHE--PKLIEDPVVVELAKKHNTS 234
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKW 329
VP V L + + ++PKSV RI +N ++ D +LTPE+ L + D G + T W
Sbjct: 235 VPLVLLAWALRQNVGIVPKSVTPSRIVENFKVIDIALTPEDIQSLTALDRGQHYIRCTGW 294
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 135 bits (327), Expect = 1e-30
Identities = 86/272 (31%), Positives = 139/272 (51%), Gaps = 16/272 (5%)
Query: 49 WLGH-RPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRE 107
WL RP+ + +T + +++ ALE GY HIDTA Y +V A+ K G+ RE
Sbjct: 35 WLKKGRPEEEQNTLTTELVDSILLALENGYNHIDTAEVYTTHPEVAAAVKKS---GIARE 91
Query: 108 SIFITTKLWNSYHEREQVIPA----LRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVD 163
+FITTK + + + ++L+ L +YVDL+LIH P F + +
Sbjct: 92 DLFITTKYTPGFRTFPAISSGPTEFIDRALKELETDYVDLFLIHSP---FFEEKVSRGQT 148
Query: 164 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK---PSALQIELN--LNLQQP 218
W +IDAKK G + IG+SNF++E ++R P QIE + L Q P
Sbjct: 149 LESAWAEVIDAKKAGKVRHIGVSNFSKEHLERTFKVAGNPDFYPKVNQIEFHPYLQNQSP 208
Query: 219 ELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFL 278
+ KF +ENDI++ AY P +LF K E + +A+KY KT Q+ LR+
Sbjct: 209 GIIKFAQENDILIEAYGPLSTLFRIKQNGVDVEDHPLKELIPKLAEKYGKTDAQILLRYT 268
Query: 279 IELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
++ + + S +RI Q++++++F ++ E+
Sbjct: 269 LQKKILPITTSSKLDRIRQSLEVYNFEISDED 300
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 135 bits (326), Expect = 2e-30
Identities = 94/298 (31%), Positives = 154/298 (51%), Gaps = 30/298 (10%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALE-AGYTHIDTAYKYG 87
++PT LS+ +P++ LGT AV+++++ GY IDTA +YG
Sbjct: 1 MIPTTVLSNNVEMPLIGLGT----------THSGGYYHDAVLHSIKKCGYRLIDTAKRYG 50
Query: 88 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
+E Q+G A+ K S + RE +F++TKLW ++V A + S E L +Y+D+Y+IH
Sbjct: 51 VEKQLGIAV-KNCS--VPREEMFLSTKLW-PVDCGDEVYNAFQTSCEKLQTDYLDMYMIH 106
Query: 148 WPIAMFENDTLLDNVDFLD-TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 206
P D +++ + + TWR M + +SIG+SN++ E + +++ P A
Sbjct: 107 MPQLP---DWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHA 163
Query: 207 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKY 266
Q+EL+ Q +L +C E I+ M Y P A ++DE L IA KY
Sbjct: 164 NQVELHPWFHQADLKNYCDELGILTMGYCPL-----------AKGKYLEDETLCKIASKY 212
Query: 267 NKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTL 324
K+ Q+ LR+ I+ +PKS R+++N +FDF L+ E+ N L SF + R +
Sbjct: 213 QKSPAQICLRWSIQQNVPTVPKSTDCRRLKENTNVFDFELSAEDMNTLNSFSSQNRKI 270
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 135 bits (326), Expect = 2e-30
Identities = 93/287 (32%), Positives = 153/287 (53%), Gaps = 34/287 (11%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
+LS+G IP +ALGT+ P+ + ++ V ++ GY H DTA YG E +VG
Sbjct: 7 KLSNGFKIPSIALGTY--DIPRSQTAEI-------VYEGVKCGYRHFDTAVLYGNEKEVG 57
Query: 94 RALTKKFSE---GLKRESIFITTKLWNSYHEREQVIPALRKSLENLN-LEYVDLYLIHWP 149
+ K +E KRE IF TTKLWNS + ++ A+R+ L ++ L+Y+DL LIH P
Sbjct: 58 DGIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP 117
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEKPSAL 207
+ E L L+TWR M +A GL KSIG+SN+ ++ I +++ KP
Sbjct: 118 L---EGSKLR-----LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVN 169
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
QIE++ + + EL +C+ +VV A+ P + PD L+ + ++ +
Sbjct: 170 QIEISPWIMRQELADYCKSKGLVVEAFAPLCHGY-KMTNPD----------LLKVCKEVD 218
Query: 268 KTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
+ QV +R+ ++ G + LPK+ +R+E N+ ++F L+ E+ L
Sbjct: 219 RNPGQVLIRWSLQHGYLPLPKTKTVKRLEGNLAAYNFELSDEQMKFL 265
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 134 bits (325), Expect = 2e-30
Identities = 91/284 (32%), Positives = 147/284 (51%), Gaps = 37/284 (13%)
Query: 41 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 100
+P++ LGTW Q+T++T + V A + GY +DT+ YG + +G A+
Sbjct: 1 MPILGLGTW----------QLTHETARTVRAAFDLGYRMVDTSGDYGTQSAIGEAIR--- 47
Query: 101 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 160
+ GL R+ I++ TK+ E E A + +L L L+Y DL LIH P + L
Sbjct: 48 ASGLDRDDIYLVTKV----EETEDAYNATQANLRELGLDYADLILIHRPPRHGAGEEL-- 101
Query: 161 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPEL 220
WR +I A++ GLT+ IG+SN++ E I+ ++D+ E P Q+E + EL
Sbjct: 102 -------WRALIRAREDGLTRDIGVSNYSIELIEELVDATGEIPVVNQVEWSPFGHDLEL 154
Query: 221 FKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIE 280
+ N IV+ AY+P ++A R+DD L A+KY KT QV +R+ +E
Sbjct: 155 KHYADFNGIVIQAYSPL-----TRAT------RLDDAALCETAEKYGKTPAQVLIRWNLE 203
Query: 281 LGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTL 324
G V +PK+ +++NI +FDF+L + L S + + +L
Sbjct: 204 RGTVPIPKANLHSHMKENISVFDFTLEKSDLESLDSLNEHFSSL 247
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 134 bits (324), Expect = 3e-30
Identities = 93/292 (31%), Positives = 150/292 (51%), Gaps = 22/292 (7%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P++ L++ +P++ LGT+ R +G+ DT AV AL+AGY DTA Y E
Sbjct: 6 PSVLLNNDIQMPLLGLGTF---RLQGQ-----EDTYSAVDAALKAGYRAFDTAAVYRNEA 57
Query: 91 QVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+G AL + GL RE +FIT+KL + + +KSLE L L Y+DLYLIHWP
Sbjct: 58 HLGHALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWP 116
Query: 150 IAM-FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
+ + +WR + + G ++IG+SN+ E +Q ++ S P+ LQ
Sbjct: 117 GTQGLPVGDKRNPENRAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQ 176
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
+E + L Q +L C+ + AY+ G+ + + ++ IA++ +
Sbjct: 177 VEFHPKLLQNDLRGLCKIRGVCFQAYSSLGTGL-----------LLSNPVVLEIAKECGR 225
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
T QV LR+ ++ VLPKS ER+++N +LFDF ++ E+ L + D G
Sbjct: 226 TPAQVLLRWAVQQSIAVLPKSSQPERVKENGRLFDFEISEEDMERLSALDCG 277
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 133 bits (322), Expect = 5e-30
Identities = 89/287 (31%), Positives = 147/287 (51%), Gaps = 26/287 (9%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
T++L++G +P++ +G W TE++V AL+AGY IDTA Y E
Sbjct: 44 TVKLNNGIEMPIIGIGVW---------TLTPEQTEKSVGEALKAGYRLIDTARMYRNEQA 94
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
VGRA+ G+ RE IFITTK++ S + A+ + L L+ +Y+DL L+H+P
Sbjct: 95 VGRAVR---DSGIPREEIFITTKIYGS-GDYANAEAAINERLRLLDTDYIDLLLLHYPD- 149
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
+NDT W+ M K G ++IG+SN++++ RI+ + P+ +Q E+
Sbjct: 150 --QNDT--------KAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEV 199
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVP 271
++ Q + F R + A+ P G + D +VS+A+KY K+
Sbjct: 200 HIYNQDKQTKAFLRNYGTQMEAWYPLGGR--NSYGNGGKDVLFADPTIVSLAKKYAKSPA 257
Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
QV LR+ ++ G + +P S + I +NI +FDF+L+ +E L D
Sbjct: 258 QVLLRWQLQAGNIAIPGSSNPAHIRENIDIFDFALSDDEMATLSRLD 304
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 133 bits (322), Expect = 5e-30
Identities = 82/259 (31%), Positives = 140/259 (54%), Gaps = 24/259 (9%)
Query: 58 VVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWN 117
V ++ E ++AL+ GY +DTA Y E +VG A+ K GLKRE I++TTKL
Sbjct: 28 VFRLETGCEDVCLFALKNGYRMLDTADIYQNEKEVGSAVRKS---GLKREDIYVTTKLKP 84
Query: 118 SYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKL 177
S + ++S++ L++ YVDL+LIH P N+ + + ++ K+
Sbjct: 85 SEEGHSNALKYAKESIKKLDIGYVDLFLIHTPRP--------GNI--IAAYDALLTLKEE 134
Query: 178 GLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPF 237
GL +S+G+SNF ++ + +G P+ QIE+N +Q E+ K+C ++ I V Y P
Sbjct: 135 GLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYCNKHGITVEGYAP- 193
Query: 238 GSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQ 297
+F + D LV ++++Y KTV Q+ +R+ ++ + +PKS + ERI +
Sbjct: 194 --VFRGC--------KFDHPVLVEMSERYGKTVAQIMIRWSVQKQYITIPKSSNPERILE 243
Query: 298 NIQLFDFSLTPEEFNLLKS 316
N Q+FDF ++ ++ L S
Sbjct: 244 NAQVFDFVISEKDMKNLVS 262
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 133 bits (322), Expect = 5e-30
Identities = 97/306 (31%), Positives = 152/306 (49%), Gaps = 48/306 (15%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQA----------VIYALEAGYTHI- 80
T +L++G IPV+ LGTW G+V + +A + L GY +
Sbjct: 13 TFKLNTGAEIPVIGLGTW--QSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALH 70
Query: 81 ---------DTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRK 131
D A+ YG E++VG+ + + G+ R +F+TTK+W +YH + + L +
Sbjct: 71 PLYIPFLAKDAAWIYGNENEVGQGIK---ASGVPRSELFVTTKIWCTYHRQPEA--CLDE 125
Query: 132 SLENLNLEYVDLYLIHWPIAMFEN-DTLL----DNVDFLD-------TWRGMIDAKKLGL 179
SL+ L L+YVDL L+HWP+ + + D + D +D TW M G
Sbjct: 126 SLQRLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGK 185
Query: 180 TKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 239
TK+IG+SN++ + +++ P+A Q+EL+ L Q EL K+C + I+ AY+P GS
Sbjct: 186 TKAIGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPLGS 245
Query: 240 LFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNI 299
+ P + DER+ SIA+ + QV + + + G V LPKSV RIE N
Sbjct: 246 ---------SGGPVLQDERVQSIAKAHKADPAQVVISWAAQRGVVALPKSVTPSRIETNG 296
Query: 300 QLFDFS 305
+L S
Sbjct: 297 KLIVLS 302
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 133 bits (321), Expect = 7e-30
Identities = 95/287 (33%), Positives = 152/287 (52%), Gaps = 37/287 (12%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
I + +L+ G +IP + LGT G V E+ V A++ GY HIDTA+ YG
Sbjct: 3 ITDSFKLNDGHSIPALGLGT----ASDGNV-------EEVVYAAIKNGYRHIDTAFIYGS 51
Query: 89 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E VG+ + + E L KRE++F+TTK+W +++ R V +L SL++L+L+YVDL L+H
Sbjct: 52 EVDVGKGIKRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVH 109
Query: 148 WPIAMF------------ENDTLLDNVDFLDTW---RGMIDAKKL-GLTKSIGISNFNQE 191
WP+++ D + D LD W I+ +KL G TKSIG+SN ++
Sbjct: 110 WPVSLLADSDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEV 169
Query: 192 QIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPP 251
++R++D P+ Q E++ L Q + +F ++ I+V A++P GS + + P
Sbjct: 170 YLKRLLDQVKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSPLGSSTGALKLHENP- 228
Query: 252 PRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQN 298
V IAQK+N + V + + + VLPK+ ER+ N
Sbjct: 229 ------IAVEIAQKHNTSTGSVLINWHVSQKRAVLPKTRSIERVVAN 269
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 132 bits (320), Expect = 1e-29
Identities = 96/288 (33%), Positives = 147/288 (51%), Gaps = 34/288 (11%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
+ L++G IP V LGT+L +D + AV YAL+ YT IDTA Y E V
Sbjct: 4 ITLNNGITIPQVGLGTYLLE---------PDDAQSAVTYALDNDYTLIDTANVYVNERAV 54
Query: 93 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
GR + + R+ IF+ TKLW S+ ER A+ ++LE L +Y+DL ++H P
Sbjct: 55 GRGMR---ASSKARDEIFLETKLWPSFFERAS---AVEETLERLGTDYIDLMILHQPAG- 107
Query: 153 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 212
D + +R + A K G ++IG+SNF+ Q QRI+D P+ Q+E +
Sbjct: 108 ----------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVECH 157
Query: 213 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQ 272
Q EL ++++I + A+ P G + P + +A++++K+ Q
Sbjct: 158 PYFPQTELKALLKDHNITLQAWYPLGGRGNDSIMSE---PIVQ-----GLAEEHSKSPAQ 209
Query: 273 VALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
V LR+ I+ G +V+P S I QNI LFDF+LT E+ + S D G
Sbjct: 210 VLLRWHIQQGHIVIPGSKTPSHIAQNIDLFDFALTDEDMAQIDSLDKG 257
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 132 bits (320), Expect = 1e-29
Identities = 85/261 (32%), Positives = 132/261 (50%), Gaps = 22/261 (8%)
Query: 63 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 122
N AV+ ALE G HIDTA YG E VG A+ + G+ RE +FITTK+W +
Sbjct: 30 NAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAIN---TSGIPREELFITTKVWTENLTK 86
Query: 123 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 182
E+ ++ SL L +Y+DL LIHWP+ N V++L + ++D GLT+
Sbjct: 87 ERFETSVIDSLTALQTKYLDLLLIHWPL----NSDEPSMVEYLSELKAVLDK---GLTRR 139
Query: 183 IGISNFNQEQI-QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLF 241
IG+SNF Q+ Q I G Q+E++ L ++ FCR+++++V Y PF
Sbjct: 140 IGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLINRKVTDFCRQHNVLVTGYMPF---- 195
Query: 242 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQL 301
A + DE +V++A + T Q+ L +L +LG +P S ++ + N+
Sbjct: 196 -------AYGAVLQDETIVNLASVHQATPAQIVLAWLRQLGFATIPSSTKRDNVRSNLAA 248
Query: 302 FDFSLTPEEFNLLKSFDTGYR 322
+LTP E + D +R
Sbjct: 249 ASINLTPAEIEQINQLDRNHR 269
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 132 bits (320), Expect = 1e-29
Identities = 85/266 (31%), Positives = 134/266 (50%), Gaps = 25/266 (9%)
Query: 67 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE---GLKRESIFITTKLWNSYHERE 123
+A+ A++ GY H D AY+YG E +G + F++ G+KRE ++I +KLW ++HE E
Sbjct: 19 EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWPNFHEPE 78
Query: 124 QVIPALRKSLENLNLEYVDLYLIHWPIA---MFEND---------TLLDNVDFLDTWRGM 171
+V + ++L +L LEY+D++L+HWP+A + + D TLL TW M
Sbjct: 79 KVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKGGTLLGTTPIRKTWEAM 138
Query: 172 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 231
T+ IG+SN + ++ KP Q E L +FC N I V
Sbjct: 139 EACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYV 198
Query: 232 MAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVAL-----RFLIELGAVVL 286
AY P G + + DA P + D L +A+K N TV ++ L R+ V+
Sbjct: 199 TAYRPLG----GRCRVDAKAP-LTDPALEELAKKANLTVSELILAWHWTRWGTSGTYSVI 253
Query: 287 PKSVHKERIEQNIQLFDFSLTPEEFN 312
PKS +ER +QN++ LTP++ +
Sbjct: 254 PKSSDRERQKQNLESVKLRLTPDQMD 279
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 132 bits (318), Expect = 2e-29
Identities = 94/304 (30%), Positives = 158/304 (51%), Gaps = 25/304 (8%)
Query: 28 LIVPTLQLSSGGNIPVVALGTWLG-HRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 86
+ VP ++LS+G IP + G+ RP G+ + + AV+ A+ AG+ HIDTA Y
Sbjct: 1 MTVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEE--RELIDAVVSAINAGHLHIDTAEFY 58
Query: 87 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 146
G E Q+G A+ + G+ R+ IF+T+K + I ++ L+ L +Y DL+LI
Sbjct: 59 GTEKQIGEAIKES---GVPRKDIFLTSKTLFGLLA-DDPIESISNQLKTLQTDYFDLFLI 114
Query: 147 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 206
H P ND + N D W + + GL K+IG+SN + +++ II KP
Sbjct: 115 HVP----PNDDI--NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHV 168
Query: 207 LQIELNLNLQQPE--LFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQ 264
QIE + LQ+P + FC+++DIVV Y+P S ++ + + P D + ++A+
Sbjct: 169 NQIEFHPLLQEPTPGIVDFCKQHDIVVEGYSPLAS---NELEGEKPL----DAVVANVAK 221
Query: 265 KYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTP---EEFNLLKSFDTGY 321
+N + V LR+ + G V + S + R ++ + +FDF L+ EE + + + Y
Sbjct: 222 NHNVSPGSVLLRWATQKGIVPITTSANAGRQKEALAIFDFKLSDGEVEEISKVGAESPRY 281
Query: 322 RTLP 325
+ LP
Sbjct: 282 QRLP 285
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 132 bits (318), Expect = 2e-29
Identities = 96/299 (32%), Positives = 149/299 (49%), Gaps = 32/299 (10%)
Query: 25 SAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 84
S++L + L ++ + LG + P G+ VQ + + ALEAGY HIDTA
Sbjct: 2 SSKLTITDLLPLPNSDVKIPRLGFGVYRSPTGQCVQSS-------LRALEAGYRHIDTAQ 54
Query: 85 KYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLE--YVD 142
YG E +VG AL K G+ R +F+TTK+ + E L +S+E + YVD
Sbjct: 55 FYGNEKEVGEALRKC---GIPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVD 111
Query: 143 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGL 201
L+LIH + + + W+ + + G T+SIG+SNF + I+ + + +
Sbjct: 112 LFLIH--------SSSSGSAGRKELWQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKV 163
Query: 202 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS 261
P QIEL+ QQ + +C+ N IVV AY+P + + +D LV
Sbjct: 164 WPPHVNQIELHPWCQQRVIEAYCKRNGIVVEAYSPLVRNY-----------KANDPTLVD 212
Query: 262 IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTG 320
+A+KY +T Q+ +R+ ++ G V LPKS ERI N +FDF + E+ +L D G
Sbjct: 213 VAKKYERTTAQILIRYALQKGWVPLPKSDTPERIVANANVFDFEIGEEDLAVLNGLDQG 271
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 131 bits (316), Expect = 3e-29
Identities = 86/304 (28%), Positives = 148/304 (48%), Gaps = 32/304 (10%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
VPT++L++G +P + +GT+L V ++ + V +A++ G+ IDTA YG E
Sbjct: 29 VPTVKLNNGMEMPQLGVGTFL----------VKDNAAERVCHAIKVGFRLIDTAQGYGNE 78
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+VG + + G+ R +FITTK+ V +L KSL +L +Y+DL LIHWP
Sbjct: 79 KEVGEGICRS---GIDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP 135
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 209
+ +TW+ + + G +SIG+SNFN + +++ +P QI
Sbjct: 136 V----------KGHIKETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVVNQI 185
Query: 210 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
E+ + Q ++ + I V A+ P G +DD + IA ++ K+
Sbjct: 186 EIEPYMTQHDVVGYTFRKGIQVEAWGPLGQGVTGV---------LDDPAIGEIAARHGKS 236
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKW 329
QV LR+ ++ G V +P+ + ++NI++FDF L+P E ++ + R Q
Sbjct: 237 AAQVILRWHMQRGLVTIPRCDNDAYTDENIRIFDFELSPSEMEIITGLNRNQRAYEQNDP 296
Query: 330 SKHP 333
P
Sbjct: 297 DNFP 300
>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
clavatus
Length = 283
Score = 131 bits (316), Expect = 3e-29
Identities = 89/262 (33%), Positives = 137/262 (52%), Gaps = 25/262 (9%)
Query: 62 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHE 121
T Q+ + AL+AGY +IDTA Y E +VG AL + G+ R +F+TTK+ +
Sbjct: 32 TRQCVQSCLTALQAGYRNIDTAQFYANEQEVGEALR---TSGIPRSDVFVTTKILSPAGS 88
Query: 122 REQVIPALRKSLENLNLE--YVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGL 179
E L +S+E + E YVDL+LIH + + + W+ + + G
Sbjct: 89 PEATYKKLLESVEKIGGENGYVDLFLIH--------SSSSGSAGRKELWQALEKLLEEGK 140
Query: 180 TKSIGISNFNQEQIQRI-IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 238
TKSIG+SNF + I+ + + + P QIEL+ QQ + +C+ N IVV AY+P
Sbjct: 141 TKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYCKRNGIVVEAYSPLV 200
Query: 239 SLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQN 298
+ + +D LV +A+KY KT QV +R+ ++ V LPKS ERIE N
Sbjct: 201 RNY-----------KANDPTLVDLAKKYGKTTAQVLIRYALQKHWVPLPKSDTPERIEAN 249
Query: 299 IQLFDFSLTPEEFNLLKSFDTG 320
++FDF ++ E+ +L + D G
Sbjct: 250 TKVFDFEISEEDMAVLNALDQG 271
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 130 bits (315), Expect = 4e-29
Identities = 83/258 (32%), Positives = 131/258 (50%), Gaps = 24/258 (9%)
Query: 68 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIP 127
AV A+E GY DTA Y E VG+A+ + RE +FI++K+WN ++ +
Sbjct: 36 AVEKAIEVGYRLFDTAAVYNNEAIVGQAI---LDSAVPREELFISSKVWNGDLGYDETLF 92
Query: 128 ALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISN 187
A ++L NL L+Y+DLYLIHWP+A + D+WR M L KSIG++N
Sbjct: 93 AFERTLRNLKLDYLDLYLIHWPVA----------GKYRDSWRAMERLHDEKLIKSIGVAN 142
Query: 188 FNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQP 247
F Q + ++ + EKP Q+E + L Q +L K+ E +I A++P
Sbjct: 143 FKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKYLAEQNIAHAAWSPL---------- 192
Query: 248 DAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLT 307
A + + + IA+K+ +V QV L++ + ++ PKS+ RIE+N +L F L
Sbjct: 193 -AKGILMQNPVITEIAKKHQASVDQVILQWHLNRNTIIFPKSITSSRIEENSRLSYFQLD 251
Query: 308 PEEFNLLKSFDTGYRTLP 325
+ + +TG R P
Sbjct: 252 ASDMEKIDRLETGKRVGP 269
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 130 bits (315), Expect = 4e-29
Identities = 88/293 (30%), Positives = 149/293 (50%), Gaps = 34/293 (11%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
++L++G P A G+++ +R K +V AL+ GY HID+A Y E
Sbjct: 6 VKLNNGLKCPQFAYGSYMVNRTK---------CFDSVYAALQCGYRHIDSAQMYHNEADC 56
Query: 93 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
GRA+ K E G KRE I+ T+KL N + + ++ S++ L Y+DL+L+H P
Sbjct: 57 GRAILKFMEETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG 115
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK-PSALQIE 210
D +++W+ + + G ++IG+SNF IQ ++DS + P QIE
Sbjct: 116 -----------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIE 164
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTV 270
L+ Q ++ +C I + AY P + +++L++IA KYNK+
Sbjct: 165 LHPFCSQQKVVDYCESKGIQLAAYAPL-----------VHGEKFGNKQLLAIASKYNKSE 213
Query: 271 PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRT 323
Q+ +R+ ++ G +VLPKS RI++N +FDF ++ E+ L + D Y +
Sbjct: 214 AQIMIRYCLQRGFIVLPKSSTPRRIKENGDVFDFEISKEDMEKLYNLDEDYHS 266
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 130 bits (314), Expect = 5e-29
Identities = 90/296 (30%), Positives = 149/296 (50%), Gaps = 23/296 (7%)
Query: 26 AELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 85
+ L+ T + SG I + ALGT + + V+ + ++ L+ G+ HIDTA
Sbjct: 4 SNLLPKTFRTKSGKEISI-ALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEA 62
Query: 86 YGIEDQVGRALTKKFSEGLKRESIFITTKL---WNSYHE-REQVIPALRKSLENLNLEYV 141
Y + +VG AL + + RE I++TTK W S + ++ K+L L ++YV
Sbjct: 63 YNTQKEVGEALKRT---DVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYV 119
Query: 142 DLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
DL+LIH P E W +++AKK G + IGISN ++++ +
Sbjct: 120 DLFLIHSPFFTTEQT---HGYTLEQAWEALVEAKKAGKVREIGISNAAIPHLEKLFAASP 176
Query: 202 EK---PSALQIELN--LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDD 256
P QIE + L Q + +FC+E+ I+V A++P L ++ + +A
Sbjct: 177 SPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLAPL--ARVETNALA----- 229
Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFN 312
E L +A+KY KT QV LR+ ++ G + + S + R+++++ LFDF LT EE N
Sbjct: 230 ETLKRLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFDFELTDEEVN 285
>UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22;
Pezizomycotina|Rep: Aldehyde reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 295
Score = 130 bits (314), Expect = 5e-29
Identities = 88/260 (33%), Positives = 147/260 (56%), Gaps = 29/260 (11%)
Query: 65 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 124
TE+A + ALE GY HID+A Y E + A+ K G+ R IF TTK+ S E+
Sbjct: 46 TEKATLKALETGYRHIDSAKYYANEKECAVAMKKS---GIDRSKIFFTTKVPASSMSYEK 102
Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
A+ +S+ +L Y+DL L+H P E L WR +++A+K G +SIG
Sbjct: 103 AKEAIEQSVAATDLGYIDLILLHAPYGGKEGR--------LGAWRALVEAQKAGHVRSIG 154
Query: 185 ISNF---NQEQIQRIIDSGLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 240
+SN+ + E+++ I+SG+ + S Q E++ + ++ + ++ ++V+ AY+P
Sbjct: 155 VSNYGIHHLEELEEYINSGVGGEISVGQYEIHPWCAREDIVAWLKKRNVVIEAYSPL--- 211
Query: 241 FPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQ 300
+AQ R+D+ L ++A+K+NKT Q+ +R+ ++ G V LPKSV RI +N Q
Sbjct: 212 --VQAQ------RLDEPVLQNLAKKHNKTGAQILIRWSLQKGYVPLPKSVTDSRIVENTQ 263
Query: 301 LFDFSLTPEEFNLLKSFDTG 320
+FDF L+ E+ ++S +TG
Sbjct: 264 VFDFELSGED---MESLNTG 280
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 130 bits (313), Expect = 7e-29
Identities = 91/263 (34%), Positives = 133/263 (50%), Gaps = 26/263 (9%)
Query: 63 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 122
++ Q VI+ALEAG HIDTA YG E V R + G+ R IFITTK+ +
Sbjct: 23 DEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIK---DAGVARNEIFITTKVKPDNYGP 79
Query: 123 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 182
V+P++R+SLE L ++ VDL L+HWP N L D+L + + D+ GL +
Sbjct: 80 GAVMPSVRESLEKLRVDQVDLLLLHWPSP--HNKYPL--ADYLGQFAEVFDS---GLARQ 132
Query: 183 IGISNFNQEQIQ---RIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 239
IG+SNF + I R++DS + Q+E ++ +Q + +C+ I V AY+P
Sbjct: 133 IGVSNFTKAMIDESIRLLDS--RTITTNQVECHVYMQNRPIIDYCQNLGIAVTAYSPL-- 188
Query: 240 LFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNI 299
A + D L I + T Q+AL FLI G VV+P S + RI QN
Sbjct: 189 ---------ARGAVVGDPVLEEIGKARGATSDQIALAFLIAKGHVVIPSSSKRGRIMQNF 239
Query: 300 QLFDFSLTPEEFNLLKSFDTGYR 322
+ +LTP E ++ + G R
Sbjct: 240 EARKITLTPAEIKRIEGLEKGMR 262
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 129 bits (312), Expect = 9e-29
Identities = 88/311 (28%), Positives = 149/311 (47%), Gaps = 23/311 (7%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 88
+VP +L G +P + +GT+ R V AV A+ AGY +D A YG
Sbjct: 12 LVPRRELRGGATVPAIGIGTFGSDRYSPAEVAA------AVAGAVAAGYRLVDCAAVYGN 65
Query: 89 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
E QVG AL + G+ R+ +F+ +K+WN H + ++ +SL +L L+++D +HW
Sbjct: 66 EAQVGEALAGAVAGGVDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHW 125
Query: 149 PI-----AMFENDTL------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 197
P M + D D+ +L W + GL + +G SN ++ ++
Sbjct: 126 PFPNHHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLL 185
Query: 198 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRI--- 254
P+ ++EL+ QQPELF C + I + Y+P GS PS+ + D P +
Sbjct: 186 RDARIPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSPLGS--PSRPERDRTPGDVVDT 243
Query: 255 DDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQ-LFDFSLTPEEFNL 313
+D +V IA+++ V L++ + G V +P SV + N++ + + LT +E
Sbjct: 244 EDPVVVRIAREHGVHPALVCLKWAVARGQVPIPFSVKPAQYTANLRAVVEDPLTAQEVAD 303
Query: 314 LKSFDTGYRTL 324
L + D G R +
Sbjct: 304 LAAADRGERLI 314
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 129 bits (312), Expect = 9e-29
Identities = 89/253 (35%), Positives = 138/253 (54%), Gaps = 30/253 (11%)
Query: 68 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKL--WNSYHEREQV 125
AV AL+ GYTHIDTA Y E VGRA+ + + RE IF+TTK+ + E E++
Sbjct: 38 AVKNALDCGYTHIDTAMAYENEAAVGRAIEQS---SVDREDIFLTTKIKGYPEMVEYERL 94
Query: 126 IPALRKSLENLNLEYVDLYLIHW--PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 183
I A + LE L EY+DL L+HW P+A E + + L+T ++D GL I
Sbjct: 95 IEAAKGCLERLGTEYLDLLLVHWWNPLADME-----ETFNALNT---LVDD---GLVGQI 143
Query: 184 GISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPS 243
G+SNF+ +++++ + + QIE + EL +FC++ND+ V AY+P
Sbjct: 144 GVSNFSIKELKQAMRLSDAPIATNQIEYHPYWGDEELVRFCQDNDVTVTAYSPL------ 197
Query: 244 KAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIEL-GAVVLPKSVHKERIEQNIQLF 302
A ++D+ L SI +Y K+ QV++R+LI+ V +PK+ + IE NI +F
Sbjct: 198 -----AEGRAVEDDVLRSIGDRYGKSAAQVSIRWLIQQENVVTIPKAATPKHIEANIDVF 252
Query: 303 DFSLTPEEFNLLK 315
DF LT + ++
Sbjct: 253 DFELTDRDMRRIR 265
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 129 bits (311), Expect = 1e-28
Identities = 87/288 (30%), Positives = 137/288 (47%), Gaps = 31/288 (10%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
PT+ L++G +P + LGTW ++ +AV A+E GY IDTA Y E
Sbjct: 8 PTVTLANGVEMPQLGLGTW---------PMTDDEAAKAVATAIETGYRLIDTAENYKNET 58
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
VG+ + G+ R+ +F+TTK+ +H + A SLE L L+Y+DL+LIHWP
Sbjct: 59 GVGQGIR---DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWPN 115
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
D +++ + G+ GL ++IG SNF + + +G P QI+
Sbjct: 116 P--------DQGTYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGF-VPHVNQIQ 166
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTV 270
L+ +P++ IV +++P G A P + IA+ + KT
Sbjct: 167 LDPYHLRPDITAIHAAKGIVTESWSPIGRAGEMLADP----------AITRIAEAHGKTP 216
Query: 271 PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
Q+ LR+ ++ G V PKS ER QN+ +F F+LT + L D
Sbjct: 217 AQIVLRWQVQSGFVPAPKSADPERQAQNLDVFGFALTESDMAALNGLD 264
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 128 bits (309), Expect = 2e-28
Identities = 87/290 (30%), Positives = 150/290 (51%), Gaps = 36/290 (12%)
Query: 37 SGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYKYG---IED 90
+G IP + LGTW +G + + D E + A++ GYTHIDTA YG E+
Sbjct: 9 TGEEIPALGLGTWGIGGF---ETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEE 65
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
+G+A+ K F +RE +FI +K+W ++ R+ ++ +L +L+ L+ +YVDLYLIHWP
Sbjct: 66 LIGKAI-KDF----RREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP- 119
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
+ +T M + + GL + IG+SNF++ ++ I E Q++
Sbjct: 120 --------NPEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVK 171
Query: 211 LNLNLQQPE---LFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
N+ + PE L +FC++N + ++AY+P S+ L IA+ +
Sbjct: 172 YNIEDRDPERDGLLEFCQKNGVTLVAYSPLRRTLLSEK---------TKRTLEEIAKNHG 222
Query: 268 KTVPQVALRFLI-ELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
T+ Q+ L +L+ + V +PK+ E + +N++ + L+ EE LL S
Sbjct: 223 ATIYQIMLAWLLAKPNVVAIPKAGRVEHLRENLKATEIKLSEEEMKLLDS 272
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 128 bits (309), Expect = 2e-28
Identities = 92/296 (31%), Positives = 155/296 (52%), Gaps = 41/296 (13%)
Query: 37 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 96
+G + V+ +GTW + + V+ ++ YAL+ G IDTA YG ED VG A+
Sbjct: 12 TGRKVSVIGVGTWSLEGSRSENVR-------SIRYALDHGVNFIDTAEMYGTEDIVGEAI 64
Query: 97 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 156
+G +RE +FI TK+W ++ V+ + +SL+ L +YVDLY +HWP
Sbjct: 65 -----KGYRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP------- 112
Query: 157 TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL--QIELNLN 214
+V +T M G + IGISNF+ ++++ + S L K + Q+E N+
Sbjct: 113 --NPSVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAM-SALAKYRIVSNQLEYNVA 169
Query: 215 LQQPE---LFKFCRENDIVVMAYTPF--GSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
++ E ++ FCR+N + ++AY+P G +F ++ + E L I +KY K
Sbjct: 170 TREIEDEGIYDFCRKNGMAIIAYSPLSHGKIFGNE---------MILETLTDIGKKYGKR 220
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLP 325
QVAL ++I GA +PK+ + +NI+ DF+L+ E+ +K+ D+ Y+ P
Sbjct: 221 PAQVALNWIIRKGAFPIPKASKPIHMAENIESTDFTLSDED---MKTLDSLYQRHP 273
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 128 bits (308), Expect = 3e-28
Identities = 77/251 (30%), Positives = 127/251 (50%), Gaps = 24/251 (9%)
Query: 72 ALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRK 131
A++ GY DTA Y E ++G S GLKR+ F+TTK+WN+ ++ + A K
Sbjct: 40 AVDVGYRLFDTASFYHNEKELGDFFA---SSGLKRDEFFVTTKMWNTEQGYDETLRAFEK 96
Query: 132 SLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQE 191
S + L L+ VDLYL+HWP + DT F +TWR + GL ++IG+SNF
Sbjct: 97 SQKKLQLDQVDLYLVHWP----KQDT------FFETWRAVEKLYDEGLVRAIGVSNFEAH 146
Query: 192 QIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPP 251
+ R+ S P Q+E + + L ++ E IV A++P G
Sbjct: 147 HLDRLRTSANVLPVVDQLETHPHFPNQLLHRYLEELHIVHQAWSPLGR-----------G 195
Query: 252 PRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEF 311
+ ++ L+ +A+K+ K+ Q+ LR+ ++ ++PKS RI +N ++DF LT +
Sbjct: 196 GVLQEQILIDLAKKHGKSPAQIVLRWHLQNNISIIPKSETPSRIRENADIYDFELTEADM 255
Query: 312 NLLKSFDTGYR 322
++ + G R
Sbjct: 256 RQVERLNNGER 266
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 127 bits (307), Expect = 4e-28
Identities = 84/256 (32%), Positives = 135/256 (52%), Gaps = 16/256 (6%)
Query: 66 EQAVIYALEAGYTHIDTAYKYG---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 122
+ +V++AL+ GY HID A YG +E +G A+ + G+ RE +F+ TKL N +H
Sbjct: 37 KDSVLHALKIGYRHIDAALAYGWGSVERGIGAAIR---ASGVPREDVFVVTKLHNCFHAP 93
Query: 123 EQVIPALRKSLENLNLEYVDLYLI----HWPIAMFENDTLLD---NVDFLDTWRGMIDAK 175
E V + SL+NL L YV + + + ++D + F TW+ M +
Sbjct: 94 EDVEVGMNMSLKNLGLGYVPYAYTKGENYSTVRKPDGKPVVDIELSRAFDTTWKAMENLV 153
Query: 176 KLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYT 235
G K IG+SNF+ +++R++ P Q+ELN Q +L +FC E++I V AY
Sbjct: 154 DQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQLLRFCHEHEIHVTAYG 213
Query: 236 PFG-SLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKER 294
P G + P P P ++D + ++A++Y++T Q+ L LI LG V+PKS + R
Sbjct: 214 PLGCTPVPYLIGRKTPGP-LEDCTVKAMAERYSRTPAQIILAHLIMLGVSVIPKSNNLSR 272
Query: 295 IEQNIQLFDFSLTPEE 310
I +N L+PE+
Sbjct: 273 ISENFDCL-VELSPED 287
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 127 bits (306), Expect = 5e-28
Identities = 90/302 (29%), Positives = 146/302 (48%), Gaps = 22/302 (7%)
Query: 25 SAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 84
S++ I + LS+G +P LG+ VQ + + AL+ GY HIDTA
Sbjct: 2 SSQEIQKVITLSNGQKMPAFGLGS--------SRVQSVEEVTNLIRKALDVGYRHIDTAQ 53
Query: 85 KYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 143
Y E +G AL F EG KRE IF+ TK + + + +++ L+ L ++YVDL
Sbjct: 54 MYENEQFIGAALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDL 111
Query: 144 YLIHWPIAMFEND-TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
LIH P+A +D ++ W + LGL K +G+SNFN + I ++
Sbjct: 112 LLIHVPLAAPSDDYQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKI 171
Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
KP QIEL++ QQ L +F ++ +I +A++P + +E L I
Sbjct: 172 KPLVNQIELHVFNQQKNLVEFLKKVNIYPVAFSPMAKY----------NEVVKNETLNQI 221
Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
AQK N +V QV + F+ VV+P++ ER++ N + E+ L++ ++ R
Sbjct: 222 AQKQNASVAQVMIAFMYHQDVVVIPRTAKIERLQHNFDAQKLQFSEEDIQTLRNLNSNTR 281
Query: 323 TL 324
+
Sbjct: 282 VV 283
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 127 bits (306), Expect = 5e-28
Identities = 90/275 (32%), Positives = 142/275 (51%), Gaps = 33/275 (12%)
Query: 41 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 100
IP + GTW + +G+ + + T A+E GY HID A Y E +VG +
Sbjct: 11 IPRLGFGTW---QLEGEDARTSTRT------AIETGYRHIDGAAIYKNEKKVGEGIK--- 58
Query: 101 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 160
G+ R+ +F+TTK+WN ++ + A+ +SL+ L L+YV+L L+HWPI ND
Sbjct: 59 DSGIPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI----ND---- 110
Query: 161 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPEL 220
+ D + + K+ G K IGISN+NQ Q + + E +A+Q E + L Q +
Sbjct: 111 -MPIADQVGPLAEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDPI 169
Query: 221 FKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRF-LI 279
K R D++ +Y+P G +A + P I ERL A+++ KT Q+ LR+ L
Sbjct: 170 LKTARGFDMMFTSYSPLGR---GEAMSN---PAI--ERL---AEQHGKTPAQIILRWHLQ 218
Query: 280 ELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
+ +PK+ K IEQN +FDF L+ + +
Sbjct: 219 QANVAAIPKATSKAHIEQNFDIFDFELSATDMKTI 253
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 126 bits (304), Expect = 8e-28
Identities = 90/283 (31%), Positives = 136/283 (48%), Gaps = 20/283 (7%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P L L G +P++ GT + + + ALE G+ HID A YG E
Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
+VG A+ + G+ RE +FITTK+ + + V AL SLE L L+YVDLYL+H P
Sbjct: 64 EVGIAIRES---GIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLHNPY 117
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
+ N T D W+G+ K G +SIG+SNF + ++ I+++ P+ Q+E
Sbjct: 118 VI-PNLT-----DIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAINQLE 171
Query: 211 LNLNLQQP-ELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKT 269
+ LQ+ + + RE I V ++ + K P DE L SIA K+N T
Sbjct: 172 YHPYLQRSHDFIPWMRERGIEVSSFKTLAPVTVGKGGP-------LDEPLASIAAKHNIT 224
Query: 270 VPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFN 312
V L ++I V + + +ER+E+ I L EE +
Sbjct: 225 TSAVVLNWVISQNIVPITTTTKRERMEEYIAAISLQLDREELD 267
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 125 bits (301), Expect = 2e-27
Identities = 73/203 (35%), Positives = 114/203 (56%), Gaps = 17/203 (8%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 94 RALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
L K F + + KRE +FIT+KLW + H+ + V AL ++L++L LEYVDLYLIHWP +
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 153 ------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 206
+ + LL VD TW+ M G ++IG+SNF+ +++ +++ P+
Sbjct: 120 KKGSVGIKPENLLP-VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAV 178
Query: 207 LQIELNLNLQQPELFKFCRENDI 229
Q+E + + +Q +L +FC+ +
Sbjct: 179 NQVECHPSWRQTKLQEFCKSKGV 201
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 124 bits (299), Expect = 3e-27
Identities = 82/257 (31%), Positives = 128/257 (49%), Gaps = 22/257 (8%)
Query: 63 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 122
+D + AV AL+ GY HIDTA Y E +VG A++ + + R +F+TTK+W
Sbjct: 24 DDAKLAVENALDVGYRHIDTAQAYENEAEVGDAIS---ASKISRGELFVTTKVWFDNLSA 80
Query: 123 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 182
++ I +++ SL LN +YVDL L+HWP D + ++L + K+ GLT+
Sbjct: 81 DKFITSVQNSLTQLNTDYVDLLLVHWP----SPDNKVSMAEYLKELKA---CKERGLTRH 133
Query: 183 IGISNFNQEQIQRIID-SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLF 241
IG+SNF Q Q+ + G + QIE++ N Q EL +C+ N+I V AY P G
Sbjct: 134 IGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVTAYMPLG--- 190
Query: 242 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQL 301
K ++++ L IA ++ T VAL +L V +P S + + N+
Sbjct: 191 VGKV--------MENDILNDIASAHDTTPSAVALAWLSHKKIVAIPSSTNVNHMRDNLTA 242
Query: 302 FDFSLTPEEFNLLKSFD 318
LT EE + +
Sbjct: 243 KQMMLTAEEIEKIDGIE 259
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 124 bits (299), Expect = 3e-27
Identities = 81/271 (29%), Positives = 140/271 (51%), Gaps = 23/271 (8%)
Query: 63 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-------LKRESIFITTKL 115
ND E + LE GY IDTA Y E+++G+ L + ++ +KRE +FIT+K
Sbjct: 38 NDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGKKIKREDLFITSKC 97
Query: 116 WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP-IAMFENDTLLDNVDFLDTWRGMIDA 174
E + A SL+ L L+Y+D YLIHWP + + +++ TWR +
Sbjct: 98 SFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGSDSGNSIQRAQTWRALEKL 157
Query: 175 KKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN-LNLQQPELFKFCRENDIVV 231
+ +SIG+SN+ + ++ S L+ KP+ Q+E + LN Q+ +L +FC+ N I++
Sbjct: 158 YQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQK-DLLEFCKNNKIIL 216
Query: 232 MAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVH 291
+Y GSL + +++E + A+K +T Q+ LR+ +E V+PK+ +
Sbjct: 217 ESY---GSLAGGRL--------LNNESVKEFAKKVGRTPSQLLLRYCLEHNCPVIPKTEN 265
Query: 292 KERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
R+ +N + DF+L+ + N L + R
Sbjct: 266 VHRLIENQMILDFTLSDDIVNSLDKLNKDQR 296
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 123 bits (297), Expect = 6e-27
Identities = 86/295 (29%), Positives = 137/295 (46%), Gaps = 33/295 (11%)
Query: 36 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 95
++G +IP + GTW D + V AL+ GY HIDTA YG E VG
Sbjct: 7 ANGADIPKLGFGTWQLE---------DEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG 57
Query: 96 LTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 155
+ G+KRE F+TTK+W + ++++SL+ L +YVDL L+HWP+
Sbjct: 58 WKQS---GVKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV----- 109
Query: 156 DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNL 215
V +T + M + K+ G + IG+SNF + + A Q+E + L
Sbjct: 110 ----PEVPIAETMKAMNEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPYL 165
Query: 216 QQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVAL 275
Q + CR + + AY+P A DDE + IA+ +N + Q+ L
Sbjct: 166 DQNAVLTACRAAGMAMTAYSPI-----------AQGKVFDDEVITEIAKAHNVSPAQIVL 214
Query: 276 RFLIELGAVV-LPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKW 329
R+LI+ +V+ +P+S + I+ N ++ D L+ EE + S + L W
Sbjct: 215 RWLIDQDSVIAIPRSSSDKHIKSNFEIADLKLSQEETGRINSLRSPDGRLIDPDW 269
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 123 bits (297), Expect = 6e-27
Identities = 72/215 (33%), Positives = 121/215 (56%), Gaps = 11/215 (5%)
Query: 34 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 93
+L++G +P+V LGT+L + + ++TN + AL+AGY HIDTA Y E +G
Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKE----EMTN----LLRTALDAGYRHIDTAVNYQNEAMIG 60
Query: 94 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
+L F EG R+ +FI +K++ + + ++ +++KSL+ L L+YVDLY +H+P+
Sbjct: 61 ESLKTIFKEGKYSRKDLFIVSKVFPN--KGINMLESVKKSLKELQLDYVDLYYLHFPLGF 118
Query: 153 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 212
++ W + +A +LGL KSIG+SNFN + ++ KP + Q+E++
Sbjct: 119 LSEKEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVS 178
Query: 213 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQP 247
+ +QQ L KFC+ I V AY P ++ P
Sbjct: 179 VFIQQKNLIKFCQRFGIHVTAYAPLAKYTDVESNP 213
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 123 bits (297), Expect = 6e-27
Identities = 92/284 (32%), Positives = 149/284 (52%), Gaps = 31/284 (10%)
Query: 40 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 99
+IPV LGT+ R + ++V +V AL GY IDTA Y E VG+A+ +
Sbjct: 2 SIPVFGLGTF---RLQDQIVI------DSVSQALTLGYRAIDTAQIYENEAPVGQAIQES 52
Query: 100 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 159
G+ R+ +FITTK+W + ++++IP+LR+S++ L +YVDL LIHWP +
Sbjct: 53 ---GINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP-------SPN 102
Query: 160 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLEKPSALQIELNLNLQQP 218
D V + ++ AK LGLT+ IGISNF + +++ I + G E+ + QIEL+ LQ
Sbjct: 103 DEVSVAEFMSELLKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNR 162
Query: 219 ELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFL 278
+ F ++N I V +Y +L KA + + + +IA+++ T QV L +
Sbjct: 163 NVVDFAKQNGIAVTSYM---TLAYGKA--------LAEPVIKTIAEQHGATPAQVILSWA 211
Query: 279 IELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
++LG V+P S + N+ L + L+ + D R
Sbjct: 212 MQLGYGVIPSSTKAANLASNLLAQKLCLNAADMALIATLDRNER 255
>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
YvgN - Bacillus sp. NRRL B-14911
Length = 268
Score = 123 bits (296), Expect = 8e-27
Identities = 87/288 (30%), Positives = 142/288 (49%), Gaps = 28/288 (9%)
Query: 33 LQLSSGGNIPVVALGT-WLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
+ L++G +P+V GT G +TN+ + + A+E GY ID A Y E+
Sbjct: 4 ITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPE-LASAIELGYRSIDAAIMYRNEEL 62
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYH---EREQVIPALRKSLENLNLEYVDLYLIHW 148
VG L + + RE FITTK+ S +E A+ SL+N +Y+DL LIH+
Sbjct: 63 VGSVLAES---KVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLIHF 119
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
PI D V +TW + + G K+IG+SNF + + + + KP+ Q
Sbjct: 120 PIE--------DKVQLKNTWEVFEEYYEAGKLKAIGVSNFEENHLDELKEFAKVKPAVNQ 171
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
I++NL L ++ +I +A+ P KA+ E L I + Y+K
Sbjct: 172 IQINLKEPNKNLLAVLKDEEITPVAWGPM------KAEAH------QKEALDEIGKIYHK 219
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
+ Q+ L++ I+ G +V+PKS ++E N++LFDF LT E+ +++
Sbjct: 220 SGAQILLKYQIQRGVIVIPKSHNRENQASNLELFDFELTAEDIEKIEN 267
>UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 284
Score = 123 bits (296), Expect = 8e-27
Identities = 101/305 (33%), Positives = 158/305 (51%), Gaps = 42/305 (13%)
Query: 35 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQ--AVIYALEAGYTHIDTAYKYG---I 88
LS+ IPV+ LGTW +G G T D E A+ A++ G THID A Y
Sbjct: 6 LSNNIKIPVIGLGTWTIGG---GDEADTTYDKENISAIKTAIKLGITHIDNAEAYAQGHS 62
Query: 89 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 148
E+ VGRA+ GL R+S+FIT+K+ + + ++ + + SL+ LN +Y+DLYLIH
Sbjct: 63 EELVGRAIV-----GLDRKSLFITSKVSPEHLSYDNLLASAKGSLQRLNTDYIDLYLIHA 117
Query: 149 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 208
P + +DFL ++ K L + IG+SNF+ +QI+ K A Q
Sbjct: 118 PNPDIPIQETMKAMDFL------VEQK---LVRCIGVSNFSVDQIKEAQKYTKNKIVANQ 168
Query: 209 IELNLNLQ---------QPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
IE NL ++ + E+ +C+EN+I ++A+ P +K + P +I DE
Sbjct: 169 IEYNLLVRDKGRVTENMESEIIPYCQENNIFIIAWRPL-----AKGKLAKPGFKILDE-- 221
Query: 260 VSIAQKYNKTVPQVALRFLI-ELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
+A KY+KT Q+A+ +LI + G VV+ KS E +E+N+ + L E+ + L +
Sbjct: 222 --LADKYHKTQAQIAINWLISKKGIVVISKSTKVEHLEKNLGAIGWKLRQEDTDRLNNEF 279
Query: 319 TGYRT 323
RT
Sbjct: 280 INSRT 284
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 123 bits (296), Expect = 8e-27
Identities = 92/286 (32%), Positives = 139/286 (48%), Gaps = 16/286 (5%)
Query: 35 LSSGGNIP---VVALGTWLGHRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIED 90
L++G IP ++ GT RP G +++ + + YAL G HID A YG
Sbjct: 10 LNNGNQIPSISIIGTGTRWFKRP-GSEHTFSDELVEQIKYALSLPGIIHIDAAECYGTYP 68
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
++ +AL K+ S+ R IFIT K I L L+ L L+YVDLYLIH P
Sbjct: 69 ELAKAL-KESSK--PRSEIFITDKYSTQTKFTNDPIEGLNTGLKTLGLDYVDLYLIHSP- 124
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
F + ++ W+ M K G KSIG+SNF+ + I+ I+ KP QIE
Sbjct: 125 --FFDPEFKGSLTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGIKPQVNQIE 182
Query: 211 LN--LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
N L Q P + +C++N+I + AY+P G P + +P+ + +A KY K
Sbjct: 183 FNAFLQNQTPGIVNYCQKNNIQLEAYSPLG---PLQKRPENSNELPFYNYIDELASKYGK 239
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
T Q+ L ++ G + + S +RI +F F+LT +E + L
Sbjct: 240 TDSQILLNWVYNRGILPITTSSKTQRIIDAQNIFSFNLTKDEVDTL 285
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 122 bits (293), Expect = 2e-26
Identities = 94/309 (30%), Positives = 158/309 (51%), Gaps = 46/309 (14%)
Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
++ + NIPV+ LGTW + G+ D V L GY HIDTA YG E +V
Sbjct: 8 IRTAGQANIPVLGLGTW---QSTGQ------DCIDVVSQGLRMGYEHIDTAQAYGNEVEV 58
Query: 93 GRALTKKFSEGLKRESIFITTKLW--NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
G+ + + G+ R+ F+TTK++ + E E+++ A ++SLENL+ +YVDL L+HWP
Sbjct: 59 GKGIKQS---GVARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWPD 115
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG--LEKPSAL- 207
D V +T + + +K GLT++IG+SNFN I II++ + P +
Sbjct: 116 ---------DRVPLSETIPALCELQKQGLTRNIGVSNFN---IANIIEAKRYADVPIVVN 163
Query: 208 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYN 267
Q+E + ++Q L F + I++ AY+P A+ D D++ + IA K+
Sbjct: 164 QVEFHPFIKQKTLQTFLNNHHILLEAYSPL-------ARGDV----FDNKIIKDIADKHG 212
Query: 268 KTVPQVALRFLI-ELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQ 326
T QV+L +++ + + +PK+ + E ++ N+ L+ +E + G
Sbjct: 213 ITAAQVSLAWILSDKHRIAIPKTSNPEHLQGNLDAIKVELSADELEKI-----GSLARSD 267
Query: 327 TKWSKHPDY 335
+ KHPDY
Sbjct: 268 GRKIKHPDY 276
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 121 bits (291), Expect = 3e-26
Identities = 84/254 (33%), Positives = 126/254 (49%), Gaps = 27/254 (10%)
Query: 66 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQV 125
E V + GY +DTA Y E+ VG L + + FITTKL R
Sbjct: 31 ESMVALGYDLGYRAVDTAAWYENEEGVGEGLRSRHARS------FITTKLMPQDMGRVNC 84
Query: 126 IPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGI 185
AL KS+ NL + ++LYLIHWP D + +TW+ +I + +G SIG+
Sbjct: 85 FVALDKSIRNLGVTSLNLYLIHWPGQ--------DRKRYEETWQTLIQIRAIGKASSIGV 136
Query: 186 SNFNQEQIQRII-DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 244
SNF + + II DSG+ P+ QIEL+ QQ EL + E IV +++P G
Sbjct: 137 SNFTIDHLDHIIADSGV-VPAVNQIELHPYFQQKELRAYHAERGIVTTSWSPLGR----- 190
Query: 245 AQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDF 304
++D + IA K+ KT QV L + + LG V+PK+ K R+++N++ F
Sbjct: 191 ------GAALNDPVIREIALKHGKTPAQVVLNWHLSLGLTVIPKASSKARLQENLEADSF 244
Query: 305 SLTPEEFNLLKSFD 318
+L E+ ++S D
Sbjct: 245 ALDEEDMQRIESLD 258
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 121 bits (291), Expect = 3e-26
Identities = 90/283 (31%), Positives = 141/283 (49%), Gaps = 31/283 (10%)
Query: 41 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 100
+P LGT+ R K +VV +V AL GY IDTA Y E QVG+A+
Sbjct: 3 VPAFGLGTF---RLKDQVVI------DSVRNALALGYRAIDTAQIYDNEAQVGQAIA--- 50
Query: 101 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 160
G+ R+ +F+TTK+W R+ + P+L++SL L +YVDL LIHWP + D
Sbjct: 51 DAGVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP-------SPKD 103
Query: 161 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLEKPSALQIELNLNLQQPE 219
V + + DAK GLT++IG+SNF ++ I+ G + + QIE++ LQ
Sbjct: 104 QVPMREYLEALADAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVHPYLQNRT 163
Query: 220 LFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLI 279
L F RE I V +Y A + D + +IA++++ T QV L + +
Sbjct: 164 LIAFLREQGIHVTSYMTL-----------AVGEVLKDPVIQAIARRHDATPAQVTLAWAL 212
Query: 280 ELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
+ G V+P S + +E N++ L+ ++ + + D G R
Sbjct: 213 QQGYSVIPSSTKRANLESNLKAQSLHLSEQDMAEIAALDRGER 255
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 121 bits (291), Expect = 3e-26
Identities = 82/258 (31%), Positives = 138/258 (53%), Gaps = 23/258 (8%)
Query: 63 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHE 121
N+ V AL++GY HIDTA YG ED G+A+ + +KR IF+T+KL N +
Sbjct: 32 NECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCEKNNVKRTDIFLTSKLANC-SD 90
Query: 122 REQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTK 181
A+R SL +L Y+DL+LI P ++ + +W+ M + G +
Sbjct: 91 YYSTRAAIRSSLHHLGT-YIDLFLIQSPAGGKKSR--------IASWKAMEEFVDSGDIR 141
Query: 182 SIGISNFNQEQIQRIIDSGLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 240
S+G+SN+ + +Q + S + P QIEL+ L Q ++ K+C+ +DI + AY+P
Sbjct: 142 SVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKYCQSHDIAIEAYSPLTHG 201
Query: 241 FPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQ 300
R++DE+LV IA+K N +V Q+ +R+ ++ G + + KS KE + ++
Sbjct: 202 I-----------RLNDEKLVPIAKKLNISVAQLLIRWSLQKGYIPIIKSTKKEHMLSDLD 250
Query: 301 LFDFSLTPEEFNLLKSFD 318
+F+F++ + L SFD
Sbjct: 251 VFNFTIPDDVVQELSSFD 268
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 120 bits (289), Expect = 5e-26
Identities = 69/187 (36%), Positives = 101/187 (54%), Gaps = 9/187 (4%)
Query: 155 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 212
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 213 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQ 272
L Q L FC+ D+ V AY P G S D ID+ + IA+++ K+ Q
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLGG---SCEGVDL----IDNPVIKRIAKEHGKSPAQ 251
Query: 273 VALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKWSKH 332
+ +RF I+ +V+P S+ I++NIQ+FDF LT + + + S + R H
Sbjct: 252 ILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNH 311
Query: 333 PDYPFQL 339
DYPF +
Sbjct: 312 NDYPFHI 318
Score = 94.7 bits (225), Expect = 3e-18
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 10/113 (8%)
Query: 39 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 98
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 99 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
>UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG07276.1 - Gibberella zeae PH-1
Length = 284
Score = 120 bits (288), Expect = 7e-26
Identities = 84/258 (32%), Positives = 136/258 (52%), Gaps = 27/258 (10%)
Query: 68 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH--EREQV 125
AV+ AL AGY HID+A Y E +V A+ + G+ RE +F+TTK+ + E+ +
Sbjct: 38 AVLAALPAGYRHIDSAALYRNEVRVREAIEQS---GVFREDLFLTTKVGSPRRKTEKTEA 94
Query: 126 IPALRKSLENLNLE--YVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 183
+ +++E + + YVDL L+H P E+ L W M AK+ ++I
Sbjct: 95 YEDVIEAVERIAGKDGYVDLLLMHVPGPSREHRHSL--------WEAMERAKREARARNI 146
Query: 184 GISNFNQEQIQRIIDSGLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFP 242
G+SNF + + + E PS QIEL+ QQ E+ K+C++N+I++ AY+P
Sbjct: 147 GVSNFRVRHLDEMKEYATEWPPSVNQIELHPWCQQKEVVKYCQDNEIIIEAYSPL----- 201
Query: 243 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLF 302
A R++D + I+ K++K+ QV +R+ ++ G V LPKS +RI +N +F
Sbjct: 202 ------ATGARLEDPLVEGISTKHDKSHAQVLIRYSLQKGWVPLPKSSRPDRISENFNVF 255
Query: 303 DFSLTPEEFNLLKSFDTG 320
DF L ++ L D G
Sbjct: 256 DFVLDEDDMETLDDLDKG 273
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 119 bits (286), Expect = 1e-25
Identities = 88/298 (29%), Positives = 143/298 (47%), Gaps = 23/298 (7%)
Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
+ +L +G +P + LGT+ G KV + V A++AGY HID A YG E+
Sbjct: 7 SFRLVNGSTLPAIGLGTFQGDDGNEKVKNI-------VKAAIQAGYRHIDGAAAYGNEEA 59
Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
+G A+ + G+ R+ +L +HE + V AL SLE L LEYV + P
Sbjct: 60 IGDAIKES---GISRD------ELAQPWHEPKDVERALDLSLEALGLEYVPHAYLPGP-- 108
Query: 152 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 211
N + + +TW+ M G K+IG+SNFN + +RI++ +P+ Q+E
Sbjct: 109 --NNVDYERSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEA 166
Query: 212 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAP-PPRIDDERLVSIAQKYNKTV 270
+ Q EL FC + I +MA+ P G P A P + D ++ IA + T
Sbjct: 167 HPYFPQHELLAFCEKEHIHLMAHQPLGGKPVGVVAPHADIPGPLFDTKIAQIAAQTGMTP 226
Query: 271 PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTK 328
QV L + ++ G ++PK+ ++ R+ +N L L+ E F ++ T + P +
Sbjct: 227 AQVILSWAVQRGTSIIPKTSNESRLSEN--LCTAPLSEEHFAIIDGLATTIESGPNVE 282
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 119 bits (286), Expect = 1e-25
Identities = 92/280 (32%), Positives = 140/280 (50%), Gaps = 40/280 (14%)
Query: 42 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
P V LGT+ G V ++AV+ AL GY HIDTA YG E +VG A+ +
Sbjct: 47 PAVGLGTFQGDAGNRGV-------KEAVLQALRCGYRHIDTATAYGNEIEVGEAIKES-- 97
Query: 102 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEY---VDLY------LIHWPIAM 152
+ RE I +TTKL ++H V AL SLE L L Y + LY + H
Sbjct: 98 -RIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPG 156
Query: 153 FENDTL--------LDNV---DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
+N+T+ +D+ D+ TW M G K IG+SNFN +++R++ S
Sbjct: 157 PDNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSAR 216
Query: 202 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS 261
P+ QIEL+ L Q EL +FC+ N I ++A+ P G + P+A P
Sbjct: 217 IPPAVNQIELHPYLPQVELVRFCKANGIHLVAHQPLGGKPVAAVNPNADRP--------- 267
Query: 262 IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQL 301
A K+ ++ Q+ L ++++ G V+PK+V + R+ +N+ L
Sbjct: 268 -ASKHERSPAQIILSWIVQQGISVIPKTVRQSRMVENLDL 306
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 118 bits (285), Expect = 2e-25
Identities = 80/243 (32%), Positives = 125/243 (51%), Gaps = 23/243 (9%)
Query: 64 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 123
+ E+ + ALEAG+ H DTA Y E +GRAL + G +RE +F+TTK+W + +
Sbjct: 25 EVERIIPAALEAGFRHFDTAQIYQNEAALGRALERA---GARREDLFLTTKVWVDNYSAD 81
Query: 124 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 183
+ ++ +SLE L ++ VDL L+HWP + ++ L+ K G T+ I
Sbjct: 82 KFAASVDESLEKLKVDQVDLLLLHWPA---HEVPVAAQIERLNA------VKDAGKTRFI 132
Query: 184 GISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPS 243
G+SN N Q++ I Q+EL+ L Q L R++ + V AY +G
Sbjct: 133 GVSNQNIAQMRESIARSAAPIVTNQVELHPYLPQHSLVAAARDSAVAVTAY--YG----- 185
Query: 244 KAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFD 303
D P+ D L I +Y K+ QV LR+L++ G V L K+ + R+ +NI +FD
Sbjct: 186 --MADGAVPK--DPVLQQIGARYGKSAAQVGLRWLVQQGYVALSKTANPARVAENIAIFD 241
Query: 304 FSL 306
F+L
Sbjct: 242 FAL 244
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 118 bits (283), Expect = 3e-25
Identities = 84/293 (28%), Positives = 142/293 (48%), Gaps = 31/293 (10%)
Query: 40 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 99
+IP + LGTW P D +AV+ +EAGY IDTA Y ED VG AL +
Sbjct: 3 DIPPLGLGTWPLTGP---------DATRAVLSGIEAGYRLIDTATIYDNEDAVGVALAEC 53
Query: 100 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 159
G+ RE +F+TTKL S H + A+ +SL+NL L+ +DL+LIHWP+
Sbjct: 54 ---GVPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPLPRHNR---- 106
Query: 160 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPE 219
++ + M+ + GL + +G+SNF + ++R++ E P+ QI+++ +L +
Sbjct: 107 ----YVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSLARLP 162
Query: 220 LFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLI 279
+ + E + +++P G + + P D IA++ ++T QV L +
Sbjct: 163 VRRADDELGVSTQSWSPLG-----RGEVLGSPVVTD------IARRLDRTPAQVVLAWHF 211
Query: 280 ELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKWSKH 332
G V + +S + R +N+ D LT + + L D G + +H
Sbjct: 212 AQGVVPVARSANPARQAENLAALDVRLTAADVDALNRLDRGESAARDVETEEH 264
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 118 bits (283), Expect = 3e-25
Identities = 86/273 (31%), Positives = 133/273 (48%), Gaps = 36/273 (13%)
Query: 30 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 89
+PT L SG +P + LGT+ + +V AL +GYTHIDTA Y E
Sbjct: 34 IPTQTLPSGDTLPALGLGTY---------ALDDDQIADSVRAALSSGYTHIDTAEGYHNE 84
Query: 90 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
+ +G L + R+ +F+T+K+ E +I + SLE L +Y+DLYLIHWP
Sbjct: 85 EAIGEVLAE-----YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHWP 139
Query: 150 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL-Q 208
N + ++ + M + GL +++G+SNF+ Q+ + E P A+ Q
Sbjct: 140 -----NPA----ISLRESLQAMAELHDRGLVRNVGVSNFSAYQLS-CANHISEVPIAVNQ 189
Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
IE + Q+P L +C E+D V+ A A P A DDE + +A+ Y+K
Sbjct: 190 IEFHPWFQRPNLVDYCHESDTVIEA-----------AAPLARTEVFDDEVVAELAESYDK 238
Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQL 301
+ QV LR+ ++ V LP+S E + N L
Sbjct: 239 SPAQVILRWALDRDVVALPRSSTPEHVRANADL 271
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 117 bits (281), Expect = 5e-25
Identities = 80/250 (32%), Positives = 125/250 (50%), Gaps = 32/250 (12%)
Query: 61 VTNDTEQAVIYA-LEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSY 119
+ DT Q + A L GY H+DTA Y E ++G AL RE +F+T+K+ +
Sbjct: 9 IDGDTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD-----YDREDVFLTSKVLPKH 63
Query: 120 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGL 179
+ E VI A SL+ L +Y+DLYL+HWP N +T M G
Sbjct: 64 LDYESVIEACEASLDRLGTDYLDLYLVHWP-----NPA----TSIRETMNAMATLHDQGK 114
Query: 180 TKSIGISNFNQEQI---QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 236
+++G+SNF+ Q+ Q + D + + QIE + Q ++ +FCR+ D VV A P
Sbjct: 115 IRNVGVSNFSAYQLGAAQHVADVPI---AVNQIEYHPWNTQDQVVEFCRDTDTVVEAAAP 171
Query: 237 FGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIE 296
G +K D+ + +++KY+++ Q+ L++ +E VVLPKS E +
Sbjct: 172 LGR---TKV--------FADDIIQDLSEKYDRSPAQIVLKWAVENNVVVLPKSSSPEHVR 220
Query: 297 QNIQLFDFSL 306
QN LFD+ L
Sbjct: 221 QNFDLFDWEL 230
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 116 bits (279), Expect = 9e-25
Identities = 82/260 (31%), Positives = 131/260 (50%), Gaps = 23/260 (8%)
Query: 64 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 122
+T+QAV+ A+ AGY IDTA YG E + G+ + + + + RE +F+TTKLW S
Sbjct: 26 ETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIANAVVAREELFLTTKLWLSEFSY 85
Query: 123 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 182
E A+ SL+ L +Y DL L+H P D ++ + +A+ G KS
Sbjct: 86 EAAKGAIDDSLKKLGTDYADLILLHQPYG-----------DVYGAYKALAEAQADGKVKS 134
Query: 183 IGISNFNQ----EQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 238
IGISNF E I+ I L P QIE + Q+ + + + + A+ P G
Sbjct: 135 IGISNFYPAKFVEFIKVIKTMNLPVPQIDQIEFHPYYQEKVARQLHDKYGVQIEAWGPLG 194
Query: 239 SLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQN 298
+K P LV IA K++K+V QV LR++++ + + KSV+ R+ +N
Sbjct: 195 RT-ANKYDTFHQP------ELVEIAAKHDKSVGQVVLRWIMQSNIITVAKSVNPSRMAEN 247
Query: 299 IQLFDFSLTPEEFNLLKSFD 318
I +F+F L ++ +++ D
Sbjct: 248 IDIFNFELDDDDMKKIETLD 267
>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
reductase; n=5; Pezizomycotina|Rep: Related to 2,
5-diketo-D-gluconic acid reductase - Neurospora crassa
Length = 289
Score = 116 bits (279), Expect = 9e-25
Identities = 88/298 (29%), Positives = 146/298 (48%), Gaps = 34/298 (11%)
Query: 27 ELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 86
+++ ++LS+G +IP + LG ++ P +T +AV +AL AGY D+A Y
Sbjct: 7 DMLSRRVKLSNGLSIPQIQLGLYMMSGP---------ETTRAVRWALGAGYRGFDSAQWY 57
Query: 87 GIEDQVGRALTKKFSE-----GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
E + G+A+ S GL R+ + T+KL ++ + V ++ KS++ L Y+
Sbjct: 58 YNEREAGQAILSFLSSPENTAGLTRKDVHFTSKLRDNSTNYDAVRASISKSVKASGLGYI 117
Query: 142 DLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
DL+L+H P+ E L +W+ + DA G K G+SN+ + + ++ +
Sbjct: 118 DLFLLHSPLGGREAR--------LTSWKAVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPF 169
Query: 202 E-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLV 260
+ KP QIE + QPE+ C + IV+ AY P A R+ L
Sbjct: 170 KIKPLVNQIECHPFNTQPEIRAACEKYGIVIEAYAPL-----------ARGMRMKHPVLT 218
Query: 261 SIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
++A+KY T QV +R+ ++ G V LPKS KER+ +N + F L E+ L D
Sbjct: 219 AVAKKYGVTPAQVLVRWSVQHGFVTLPKSTKKERLVENADVGRFELAEEDMEKLDGLD 276
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 116 bits (278), Expect = 1e-24
Identities = 87/284 (30%), Positives = 138/284 (48%), Gaps = 37/284 (13%)
Query: 29 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYG 87
+VP ++ S +P + GTW Q+ N T ++ ALE GY HIDTA YG
Sbjct: 4 LVPAVR-SGDVLMPALGFGTW----------QLENGTAVPLVEKALEIGYRHIDTAQIYG 52
Query: 88 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 147
E VG A+ + G+KR+ IF+TTK+W + + KSLE L ++ VDL L+H
Sbjct: 53 NERDVGAAIR---NSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLH 109
Query: 148 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 207
WP V +T + + + G T++IG+SNF Q++ E P A
Sbjct: 110 WP---------KPEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLS-EAPIAT 159
Query: 208 -QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKY 266
Q+E + L L + + + A++P A D L+ I + +
Sbjct: 160 DQVEYHPYLSLKTLKAKADQLGVSITAWSPL-----------AQGKVAQDPVLIEIGRAH 208
Query: 267 NKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEE 310
KT QV LR++I+ G + +P++ + +RIE+N + DF L+ +E
Sbjct: 209 GKTPGQVTLRWIIQQGIIAIPRTSNPKRIEENFDILDFELSEKE 252
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 115 bits (276), Expect = 2e-24
Identities = 85/288 (29%), Positives = 142/288 (49%), Gaps = 31/288 (10%)
Query: 31 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
P L L+ G IP++ LGT H K A+ ALE G DTA YG E
Sbjct: 35 PLLTLNDGYQIPIIGLGTTSLHNQTCK---------NAIKAALEIGIRLFDTASLYGNEK 85
Query: 91 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
+VG + + + R IF+ TKL+ A+ ++L LN +Y+D+ L+H P
Sbjct: 86 EVGETIRES---NINRNEIFVITKLYPGAQFANPE-KAIEEALNKLNTDYIDMMLLHHP- 140
Query: 151 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 210
END + ++ + + G KS+G+SN+ ++I + KPS +Q E
Sbjct: 141 --GEND--------VKAYKAIEKYIEKGKIKSVGLSNWYIKEINSFLPQINIKPSLIQNE 190
Query: 211 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTV 270
+++ Q+ E+ + +I + A+ PFG + + + P +VSIA+ +NKT
Sbjct: 191 IHIYYQEKEVVPYMHNLNIAMQAWYPFGGRGHTFSVLNNPT-------IVSIAKDHNKTS 243
Query: 271 PQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
Q+ R+L++ G + + S + I++NI +FDF L+ +E L+ S D
Sbjct: 244 AQIISRWLLQRGIITIVGSSNPIHIKENISVFDFELSNQEMELIASLD 291
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 115 bits (276), Expect = 2e-24
Identities = 85/280 (30%), Positives = 135/280 (48%), Gaps = 33/280 (11%)
Query: 41 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 100
+P++ LGTW + ++V ALEAGY HIDTA Y E VG +
Sbjct: 17 MPMLGLGTWQN--------EDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIA--- 65
Query: 101 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 160
+ + R+ IF+ TK+W S + VI +SL+ L ++ VDL +HW +E + L
Sbjct: 66 AADVDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP 125
Query: 161 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP-SALQIELNLNLQQPE 219
D L RG+ID ++G+SNF ++ +D L+ P A Q+E + LQQ E
Sbjct: 126 AFDEL-VDRGLID--------NVGVSNFEPHHVETAMDV-LDAPVFANQVETHPFLQQSE 175
Query: 220 LFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLI 279
L + E D ++AY+P A + + +IA ++ + QV+L +L
Sbjct: 176 LREHAAEQDYELVAYSPL-----------ARGEVFGHDVIEAIADDHDASEAQVSLAWLR 224
Query: 280 ELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
E G +PK+ + I N+ D SLT + + + + DT
Sbjct: 225 EKGVTAIPKATSEAHITDNLASLDLSLTDADIDRIDNIDT 264
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 113 bits (271), Expect = 8e-24
Identities = 85/301 (28%), Positives = 140/301 (46%), Gaps = 28/301 (9%)
Query: 63 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHE 121
++ AV +AL GY H+D A YG E VG AL + + +RE +F+T+KLW +
Sbjct: 43 SEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDLFVTSKLWPTDQH 102
Query: 122 REQVIPALRKSLENLNLEYVDLYLIHWPIAM-----FEND------------TLLDNVDF 164
+ V A R +L L L+Y+DLYLIHWP+ M + +D + +V
Sbjct: 103 PDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHRDGTPAIDTSVTL 162
Query: 165 LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK-----PSALQIELNLNLQQPE 219
LDTW M GL KSIG++N + ++ + E P Q+E + + +
Sbjct: 163 LDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLPVLNQVEHHPGIVDGD 222
Query: 220 LFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLI 279
L +D+++ AY P G P+ + P +DD L S++ + ++ L + +
Sbjct: 223 LIGCLGSHDMLMAAYCPLG--MPTCSTPPGFQSLLDDPVLRSLSAFSGFSPARLLLNWSV 280
Query: 280 ELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD---TGYRTLPQTKWSKHPDYP 336
+ VV+ KS +E I N + F+L +L ++ +R + T +S P
Sbjct: 281 DRHNVVIVKSASREHIRSNAKAARFALDDRTRLVLDNYHLLVRNFRVMNPTHFSVDGATP 340
Query: 337 F 337
F
Sbjct: 341 F 341
>UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=3; Archaea|Rep: 2,5-diketo-D-gluconic acid reductase A
- Sulfolobus acidocaldarius
Length = 267
Score = 113 bits (271), Expect = 8e-24
Identities = 81/255 (31%), Positives = 135/255 (52%), Gaps = 32/255 (12%)
Query: 67 QAVIYALEAGYTHIDTAYKYG---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 123
+A+ Y + G IDTA YG E+ VG+A+ RES+FITTK+W ++ + +
Sbjct: 35 EAIKYTINKGINLIDTAEMYGGGHTEEIVGKAVAD-----FDRESLFITTKVWPNHLKYD 89
Query: 124 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 183
I + SL+ LN +Y+DLYLIHWP D ++ + + +ID +G+ + I
Sbjct: 90 DTIKSALASLKRLNTKYIDLYLIHWP----NPDVKVE--ETISAMEKLID---MGVVRCI 140
Query: 184 GISNFNQEQIQRIIDSGLE-KPSALQIELNLNLQQPE--LFKFCRENDIVVMAYTPFGSL 240
G+SNF+ + + + I S + + A QI+ ++ PE + F +N + ++AY+P G
Sbjct: 141 GVSNFDVKLLDQAIHSTKKYEIVANQIQYSIYRLTPERDVIPFAEKNKVTIIAYSPLGQG 200
Query: 241 FPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQ 300
S + RL IA KY KT QVAL +L + ++ +PK+V K I++
Sbjct: 201 SIS-----------SESRLKDIALKYGKTQAQVALAYL-KRRSIPIPKAVQKTHIDEIAD 248
Query: 301 LFDFSLTPEEFNLLK 315
+ F L E++N ++
Sbjct: 249 VMKFDLRDEDYNEIR 263
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 112 bits (270), Expect = 1e-23
Identities = 79/276 (28%), Positives = 133/276 (48%), Gaps = 23/276 (8%)
Query: 41 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 100
+P +GT L + KG++ + D+ V AL AG+ HID A YG E++VG AL +
Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDS---VKNALAAGFIHIDCAEVYGNEEEVGVALKEA- 67
Query: 101 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 160
+ R +FIT+K+ H + + AL +SL L +Y+DLYL+H PI +E
Sbjct: 68 --NVPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEK----- 117
Query: 161 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQ--P 218
+ + W+ M A GL S+G+SNF ++ ++ + P QIE + + +
Sbjct: 118 KIPISEGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAK 177
Query: 219 ELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFL 278
L +FC+ I+V Y P L P A E S+ KY+ + Q+ L++
Sbjct: 178 PLVEFCQSKGIIVEGYGPLSPLVRDAQGPVA-------EFTKSLESKYHVSDTQILLKWA 230
Query: 279 IELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314
G + + + ER+++ + F+L + + L
Sbjct: 231 YSKGVIPITTTSKIERMKECLNFDSFTLDKADIDEL 266
>UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Picrophilus torridus|Rep: 2,5-diketo-D-gluconic acid
reductase - Picrophilus torridus
Length = 283
Score = 112 bits (270), Expect = 1e-23
Identities = 80/285 (28%), Positives = 142/285 (49%), Gaps = 36/285 (12%)
Query: 37 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 96
+G I + +GTW ++ + + A+ L+AG +DTA Y E VGRA+
Sbjct: 8 TGERISSIGIGTWQ--------MKSNDQSIMAIRAGLDAGSNFVDTAEAYRNEAMVGRAI 59
Query: 97 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 156
+ +FI TK++ ++ + + +I A SL+ LN++ +DLY +HWP
Sbjct: 60 ESR--------EVFIATKVFPNHFKYDSLIRACENSLKRLNVKTIDLYQLHWPNR----- 106
Query: 157 TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL--QIELN-- 212
+VD +T + M G+ + IG+SNFN +++ + S + K + Q+E N
Sbjct: 107 ----HVDIKETMKAMEHLVDTGMIRYIGVSNFNVNELKSAM-SAMSKYEIVSNQVEYNPL 161
Query: 213 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQ 272
+ +PE+ +FCR+N I ++AY+P D P D+ IA K N TV Q
Sbjct: 162 VRYIEPEISEFCRKNSISIIAYSPL------MHGHDIDPISKDESPFNIIANKRNATVRQ 215
Query: 273 VALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSF 317
V L +++ +PKS E + +N++ + +L+ EE +++ +
Sbjct: 216 VILAWILSKNFFAIPKSNVPEHVIENVKSMNINLSSEETSMIDHY 260
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 111 bits (268), Expect = 2e-23
Identities = 65/178 (36%), Positives = 103/178 (57%), Gaps = 21/178 (11%)
Query: 30 VPTLQLSSGGN----IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 85
VPTL + SG + +PV+ GT P+ +++ T VI A++ GY H DT+ +
Sbjct: 6 VPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKET------VIEAIKLGYRHFDTSPR 59
Query: 86 YGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 143
Y E+ +G AL + S GL R F+TTKLW + V+PA+++SL+NL L+Y+DL
Sbjct: 60 YQTEEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDL 119
Query: 144 YLIHWPIAM--------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 193
Y+IHWP++ + D + +DF W M + ++LGL K IG+SNF+ +++
Sbjct: 120 YIIHWPVSSKPGKYKFPIDEDDFMP-MDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176
>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 301
Score = 111 bits (268), Expect = 2e-23
Identities = 84/274 (30%), Positives = 132/274 (48%), Gaps = 16/274 (5%)
Query: 59 VQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE-GLKRESIFITTKLWN 117
++ D + ++ AL++GY DTA Y E +G +L K + GL RE +FITTK+
Sbjct: 30 IETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKYLPQFGLTREDVFITTKVRT 89
Query: 118 -SYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF---ENDTLLDNVDFLDTWRGMID 173
+ + E+ L SL L +YVDL LIH+P ++D ++ W+ +
Sbjct: 90 LNENTVEETEKQLANSLATLQTDYVDLLLIHYPRDRDTGNDDDYEINKSRRKIVWQTLEK 149
Query: 174 AKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMA 233
AK+ G +SIG+SN+ + + + +P Q E L +P L KFC N+IVV +
Sbjct: 150 AKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQYEYQPYLTRPTLKKFCDLNNIVVQS 209
Query: 234 YTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKE 293
Y+ S D + ++ LV + QKYN+T + F ++PKS
Sbjct: 210 YS-------SLCWGD--KEILQEKPLVDLCQKYNQTPQAILYAFAHCSNTSMIPKSATPS 260
Query: 294 RIEQNI-QLFDFSLTPEEFNLLKSFDTGYRTLPQ 326
RI N+ LT +E L+S D G ++ PQ
Sbjct: 261 RIHDNLHNTIKIKLTEDELKSLRSLDKG-KSFPQ 293
>UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep:
Aldo / keto reductase - Thermoplasma volcanium
Length = 288
Score = 111 bits (267), Expect = 3e-23
Identities = 82/260 (31%), Positives = 137/260 (52%), Gaps = 32/260 (12%)
Query: 67 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVI 126
QA+ A++AG T IDTA YG ED V +A+ EG RE +FI TK+W ++ ++VI
Sbjct: 50 QAIRTAIDAGVTLIDTAEIYGSEDLVAKAI-----EGHNREELFIATKVWINHLRYDKVI 104
Query: 127 PALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGIS 186
A + SL LN +YVDLY IH+P + +T++ M GL K IG+S
Sbjct: 105 KACKASLSRLNTKYVDLYQIHFP---------SPTANLQETFKAMEKLVDDGLVKFIGVS 155
Query: 187 NFNQEQIQRIIDSGLEKPSALQIELNLNLQ----QPELFKFCRENDIVVMAYTPF--GSL 240
NF++ ++++ ++ ++K + +++ +L+ + ++ KFC N + V+A+ P GSL
Sbjct: 156 NFSRGKLEKSMEY-VKKYEIVSNQIHYSLKKRDAEEDIVKFCENNGMAVLAWYPLEHGSL 214
Query: 241 FPSKAQPDAPPPRIDDERLVSIAQKYNKTVP-QVALRFLIELGAVV--LPKSVHKERIEQ 297
P E L I K+ P Q+AL +LI +V +P++ + E +++
Sbjct: 215 VRESDYP--------SEILARIKAKHPSITPAQIALSYLIYGNKLVFPIPRASNPEHVKE 266
Query: 298 NIQLFDFSLTPEEFNLLKSF 317
NI + L EE L+ +
Sbjct: 267 NIASVEQKLDQEEIEELRKY 286
>UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;
Lactobacillus|Rep: Aldo/keto reductase family enzyme -
Lactobacillus casei (strain ATCC 334)
Length = 281
Score = 110 bits (265), Expect = 4e-23
Identities = 79/280 (28%), Positives = 144/280 (51%), Gaps = 27/280 (9%)
Query: 38 GGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 97
G N+P++ +GTW + +G Q + A+ Y L G T IDTA YG + +L
Sbjct: 8 GVNVPIMGMGTW--YLGEGNAAQSEQEAA-ALKYGLNHGLTVIDTAEMYG--NGAAESLI 62
Query: 98 KKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDT 157
F R +I++ +K + S+ ++ Q++ AL+ SL+ L +Y+DLYL+HW
Sbjct: 63 GSFLGDYDRANIYLISKFYPSHADKRQMLTALKNSLKRLQTDYLDLYLLHW--------- 113
Query: 158 LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGLEKPSALQIELNLNLQ 216
+ +T G+ D +K GL K G+SNF+ + + ++ ++ G ++ +A ++ NL +
Sbjct: 114 -RGSTPLAETLEGLQDLQKEGLIKQYGVSNFDVDDMDQLTLEPGGDQIAANEVLYNLQSR 172
Query: 217 QPE--LFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVA 274
E L ++ +I + Y+PFGS S PP L ++A++ N + Q+
Sbjct: 173 SIEYDLLPQQKQANITTIGYSPFGS--GSGKSIKLPP------ELRTLAKEKNISTHQLM 224
Query: 275 LRFLIELGAVV-LPKSVHKERIEQNIQLFDFSLTPEEFNL 313
L +++ G V+ +P+S + +NI D + +P+E L
Sbjct: 225 LAWVLRHGDVLTIPRSGEASHMAENIAAADVTFSPDELAL 264
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.319 0.138 0.407
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 396,157,389
Number of Sequences: 1657284
Number of extensions: 16620660
Number of successful extensions: 45626
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 382
Number of HSP's successfully gapped in prelim test: 336
Number of HSP's that attempted gapping in prelim test: 43774
Number of HSP's gapped (non-prelim): 863
length of query: 340
length of database: 575,637,011
effective HSP length: 101
effective length of query: 239
effective length of database: 408,251,327
effective search space: 97572067153
effective search space used: 97572067153
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 73 (33.5 bits)
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