BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001351-TA|BGIBMGA001351-PA|IPR001395|Aldo/keto reductase (340 letters) Database: nematostella 59,808 sequences; 16,821,457 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SB_34622| Best HMM Match : No HMM Matches (HMM E-Value=.) 208 7e-54 SB_54717| Best HMM Match : Aldo_ket_red (HMM E-Value=0) 157 1e-38 SB_7528| Best HMM Match : Aldo_ket_red (HMM E-Value=0) 121 7e-28 SB_8916| Best HMM Match : No HMM Matches (HMM E-Value=.) 110 1e-24 SB_56309| Best HMM Match : No HMM Matches (HMM E-Value=.) 102 5e-22 SB_33699| Best HMM Match : Aldo_ket_red (HMM E-Value=3.1) 53 4e-07 SB_56184| Best HMM Match : No HMM Matches (HMM E-Value=.) 49 5e-06 SB_5128| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 1e-04 SB_55921| Best HMM Match : Aldo_ket_red (HMM E-Value=0.16) 33 0.44 SB_18692| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 0.58 SB_22820| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 0.58 SB_46602| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 1.8 SB_39919| Best HMM Match : No HMM Matches (HMM E-Value=.) 30 3.1 SB_4889| Best HMM Match : No HMM Matches (HMM E-Value=.) 29 4.1 SB_50274| Best HMM Match : No HMM Matches (HMM E-Value=.) 29 5.4 SB_16678| Best HMM Match : No HMM Matches (HMM E-Value=.) 29 5.4 SB_7780| Best HMM Match : No HMM Matches (HMM E-Value=.) 29 5.4 >SB_34622| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 340 Score = 208 bits (507), Expect = 7e-54 Identities = 121/308 (39%), Positives = 181/308 (58%), Gaps = 21/308 (6%) Query: 32 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91 T++L++G +PV+ LGTW K K QV N AV +A++ GY HID AY Y E + Sbjct: 3 TVKLNNGLEMPVLGLGTW-----KSKPGQVEN----AVKFAIKEGYRHIDCAYAYRNEKE 53 Query: 92 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151 VG AL + ++R+ +FIT+KLWN+ H + V SL++L L+Y+DLYLIHWP++ Sbjct: 54 VGDALRELLGSVVERKDLFITSKLWNTKHNPKDVRSNCVDSLKDLGLDYLDLYLIHWPLS 113 Query: 152 MFENDTLL-----DNV-----DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201 + D NV D DTW+ M GL K+IG+SNFN +Q+ I Sbjct: 114 FRDGDEFFPKDEQGNVLYAYHDPCDTWKAMEKLVDEGLVKAIGLSNFNSKQVDDICAIAR 173 Query: 202 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS 261 KP A Q+E + L Q +L ++++I +AY+P GSL A+PD P + D +V+ Sbjct: 174 IKPVANQVECHPLLNQAKLIDHHKKHNIQTIAYSPLGSLDRPWAKPD-DPHVMRDPTMVA 232 Query: 262 IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321 +A +Y++TV Q+ +RF I+ G +V+PKSV ERI+ N Q+FDF L+ E+ ++ + + Sbjct: 233 MADRYSRTVAQICIRFQIQRGVLVIPKSVTPERIKSNFQVFDFELSAEDMATIEGLNRDW 292 Query: 322 RT-LPQTK 328 R LP K Sbjct: 293 RACLPMKK 300 >SB_54717| Best HMM Match : Aldo_ket_red (HMM E-Value=0) Length = 333 Score = 157 bits (381), Expect = 1e-38 Identities = 89/259 (34%), Positives = 148/259 (57%), Gaps = 24/259 (9%) Query: 65 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 124 ++QAV++ALE+GY IDTA +Y E VG A+ + R I++ TK++ + H ++ Sbjct: 88 SKQAVLWALESGYRLIDTASRYHNEQSVGEAVR---CSNIPRCEIYVVTKVYFTEHGYKE 144 Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184 + A KSL L L YVDLYLIH+P+ + +W+ MID + GL +SIG Sbjct: 145 TMDAFYKSLTRLGLGYVDLYLIHFPVPS----------GVVGSWQAMIDLRSRGLIRSIG 194 Query: 185 ISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 244 +SNFN + ++ + P+ QIE++ LQ EL ++C+ ++I + A++P +K Sbjct: 195 VSNFNIQHLEALRQQTGVVPAVNQIEVHPFLQMKELTQYCKRHNITIQAFSPL-----TK 249 Query: 245 AQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDF 304 + ++ D L +A+KYNKT Q+ +R+ ++ G +PKS ERI++N ++FDF Sbjct: 250 GE------KLCDPILSYVAKKYNKTTAQILVRWSLQKGYACIPKSAQLERIKENAKVFDF 303 Query: 305 SLTPEEFNLLKSFDTGYRT 323 S+ + L+ + YRT Sbjct: 304 SIDMADMELIDGLEENYRT 322 >SB_7528| Best HMM Match : Aldo_ket_red (HMM E-Value=0) Length = 407 Score = 121 bits (292), Expect = 7e-28 Identities = 64/168 (38%), Positives = 103/168 (61%), Gaps = 11/168 (6%) Query: 68 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVI 126 AV A+E GY HID A YG E ++G AL++ +EG +KRE +F+T+KLW H + V+ Sbjct: 70 AVRLAIELGYRHIDCAEIYGNEGEIGEALSEVLTEGKVKREELFVTSKLWCDSHHPDDVL 129 Query: 127 PALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNV----------DFLDTWRGMIDAKK 176 PA + +L+NL L+Y+DLYLIH P+A + L ++ +TW+ M Sbjct: 130 PACQATLKNLQLDYLDLYLIHIPVAFKKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVA 189 Query: 177 LGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFC 224 GL K+IG+SNF+ +++ +++++ P+ Q+EL+ L Q +L +FC Sbjct: 190 KGLCKAIGVSNFSVKRLNKLLETASIVPACNQVELHPYLPQEKLKEFC 237 Score = 58.8 bits (136), Expect = 6e-09 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 4/107 (3%) Query: 223 FCRENDIVVMAYTPFGS---LFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLI 279 FC I++ AY+P G+ L P K + + P +++ + IA K+N +V +V LR+ I Sbjct: 284 FCDSKGILLTAYSPLGNPGRLVP-KERLEREPKVMEEPVIKEIAAKHNCSVARVLLRWGI 342 Query: 280 ELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQ 326 + G VLPKS ++ + N LT +E +KS T R L Q Sbjct: 343 QRGYPVLPKSTSRDHLHDNFSALGLVLTDDEMAAIKSITTRQRYLTQ 389 >SB_8916| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 619 Score = 110 bits (265), Expect = 1e-24 Identities = 89/311 (28%), Positives = 145/311 (46%), Gaps = 26/311 (8%) Query: 22 IPQSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHID 81 IP+ E L L+SG +PV+ GT + DT V ALE GY ID Sbjct: 319 IPRKNERPADVL-LASGYTMPVMGFGT----------ATLGEDTLSVVKTALETGYRLID 367 Query: 82 TAYKYGI-EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEY 140 TA Y + E QV +A+ G+ R+ IFI TKL Y E + ++ SL L+ +Y Sbjct: 368 TAQGYPLSEPQVAKAIA---DSGIPRKDIFIITKLHPRYLGYEPTLKSVEMSLRALSTDY 424 Query: 141 VDLYLIHWPIAMFENDTLLDNVD------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 194 +DL+LIH +D LL + + ++W+ M + + G +S+G+SNFN +++Q Sbjct: 425 IDLFLIHSKTC---DDFLLTCAEGEPRGTWKESWKAMEELHRQGKIRSLGVSNFNVDELQ 481 Query: 195 RIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRI 254 +++ SA+Q + Q + +FC ++ I + Y+ G+ + P + Sbjct: 482 ELVNFATVPVSAVQNWFDPFHQDRKARRFCNKHGIRYIGYSTLGTQW-VYFHGLKTNPVL 540 Query: 255 DDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLL 314 + I+ Y + QV LR+ I V+P+S + I N + D SL E ++ Sbjct: 541 QSKVFSEISSHYEYVISQVVLRWAIHQNVTVIPRSRNSRNIYLNFRSLDLSLNENEIEMI 600 Query: 315 KSFDTGYRTLP 325 + T Y P Sbjct: 601 TNV-TDYEFHP 610 >SB_56309| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 394 Score = 102 bits (244), Expect = 5e-22 Identities = 59/179 (32%), Positives = 97/179 (54%), Gaps = 13/179 (7%) Query: 58 VVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWN 117 V ++ E ++AL+ GY +DTA Y E +VG A+ K GLKRE I++TTKL Sbjct: 39 VFRLETGCEDVCLFALKNGYRMLDTADIYQNEKEVGSAVRKS---GLKREDIYVTTKLKP 95 Query: 118 SYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKL 177 S + ++S++ L++ YVDL+LIH P N+ + + ++ K+ Sbjct: 96 SEEGHSNALKYAKESIKKLDIGYVDLFLIHTPRP--------GNI--IAAYDALLTLKEE 145 Query: 178 GLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 236 GL +S+G+SNF ++ + +G P+ QIE+N +Q E+ K+C ++ I V Y P Sbjct: 146 GLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYCNKHGITVEGYAP 204 >SB_33699| Best HMM Match : Aldo_ket_red (HMM E-Value=3.1) Length = 93 Score = 52.8 bits (121), Expect = 4e-07 Identities = 28/72 (38%), Positives = 44/72 (61%), Gaps = 3/72 (4%) Query: 65 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 124 T+QAV++ALE GY IDTA Y E +VG AL + + R +++ TK++++ H E+ Sbjct: 24 TKQAVLWALENGYRMIDTAASYNNEKRVGEALRE---SAVPRSEVYLVTKVYHTDHGYEK 80 Query: 125 VIPALRKSLENL 136 + A +SL L Sbjct: 81 TMKAYDRSLSAL 92 >SB_56184| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 242 Score = 49.2 bits (112), Expect = 5e-06 Identities = 36/151 (23%), Positives = 73/151 (48%), Gaps = 12/151 (7%) Query: 122 REQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTK 181 R+ V +++KS++ + ++ +D+ HW + +LD + + + G + Sbjct: 3 RKVVEASIQKSMKRMAVDKLDMVQFHW--------WDYSDKRYLDALLHLSELQSEGKIQ 54 Query: 182 SIGISNFNQEQIQRIIDSGLEKPSALQIELNL--NLQQPELFKFCRENDIVVMAYTPFGS 239 I ++NF+ ++Q I D G+ K S+ QI+ +L ++ KFC ++ I ++AY Sbjct: 55 EISLTNFDTNRMQEITDHGI-KISSNQIQFSLIDRRANEKMVKFCLDHGISLLAYGTIAG 113 Query: 240 LFPSKAQPDAPPPRIDDERLVSIAQKYNKTV 270 F +K P P D S+ +KY + + Sbjct: 114 GFLTKRYLGKPEPTADQLNTASL-RKYKQMI 143 >SB_5128| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2102 Score = 44.4 bits (100), Expect = 1e-04 Identities = 39/150 (26%), Positives = 63/150 (42%), Gaps = 2/150 (1%) Query: 172 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 231 +D KK K I + N E I + L K + Q ++C+EN+I Sbjct: 1287 LDLKKTVTEKIIPHAPLNPEAIDLMRMPNLAKIPFHKNFFTPFYQDKATRQYCKENNIKY 1346 Query: 232 MAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVH 291 M Y+ G ++ + D P + + E L I ++ TV QV L++ +E +V+P+S Sbjct: 1347 MGYSTLGGMYVREGF-DKNPVQNNFE-LQRIGGVFDATVSQVVLKWALEQDVLVIPQSRT 1404 Query: 292 KERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321 I N L L ++ S D Y Sbjct: 1405 PNHIRTNFHLDHVQLDSKQMAYFDSLDGLY 1434 >SB_55921| Best HMM Match : Aldo_ket_red (HMM E-Value=0.16) Length = 195 Score = 32.7 bits (71), Expect = 0.44 Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 10/59 (16%) Query: 131 KSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFN 189 KSLE L ++ +DLYL+HW E L+ + +D +R ++D G+ G+SN + Sbjct: 50 KSLERLGIDRIDLYLLHW-----EGRVPLE--ETVDAFRELVDE---GMIARWGVSNLD 98 >SB_18692| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 170 Score = 32.3 bits (70), Expect = 0.58 Identities = 36/126 (28%), Positives = 58/126 (46%), Gaps = 14/126 (11%) Query: 201 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLV 260 LEKP QI+L N+ P R + ++ P +K +A R++ ++V Sbjct: 52 LEKPH-WQIKLEDNIFAPPPLPSPRNS-----SHNPHRPRKAAKRPREAQTNRVNPGKVV 105 Query: 261 SIAQKYNKTVPQVALRFLIELG-AVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319 +A +Y P V L ++G AV +PK + KE+ E+ +L F+L + L Sbjct: 106 YVAARYEHYPPGVKLDGPGDMGEAVSVPKRL-KEKEEEGYELHSFNLVASDMMSL----- 159 Query: 320 GYRTLP 325 YR LP Sbjct: 160 -YRRLP 164 >SB_22820| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 167 Score = 32.3 bits (70), Expect = 0.58 Identities = 36/126 (28%), Positives = 58/126 (46%), Gaps = 14/126 (11%) Query: 201 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLV 260 LEKP QI+L N+ P R + ++ P +K +A R++ ++V Sbjct: 49 LEKPH-WQIKLEDNIFAPPPLPSPRNS-----SHNPHRPRKAAKRPREAQTNRVNPGKVV 102 Query: 261 SIAQKYNKTVPQVALRFLIELG-AVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319 +A +Y P V L ++G AV +PK + KE+ E+ +L F+L + L Sbjct: 103 YVAARYEHYPPGVKLDGPGDMGEAVSVPKRL-KEKEEEGYELHSFNLVASDMMSL----- 156 Query: 320 GYRTLP 325 YR LP Sbjct: 157 -YRRLP 161 >SB_46602| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1805 Score = 30.7 bits (66), Expect = 1.8 Identities = 16/47 (34%), Positives = 23/47 (48%) Query: 105 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151 K + + T+ H+RE + LR+ LE L EY DL H I+ Sbjct: 871 KVKPLLNVTRQEEELHQREDELRTLREKLEKLETEYTDLEKKHSQIS 917 >SB_39919| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 122 Score = 29.9 bits (64), Expect = 3.1 Identities = 15/56 (26%), Positives = 27/56 (48%), Gaps = 3/56 (5%) Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTND---TEQAVIYALEAGYTHIDTAYK 85 + L+ +P + W+GH P G + ND T QAV+ + +G +++ K Sbjct: 54 ISLTGDAIVPGLYCSGWVGHGPVGVIATTMNDAYATGQAVVEDINSGLLKAESSTK 109 >SB_4889| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 151 Score = 29.5 bits (63), Expect = 4.1 Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 3/41 (7%) Query: 33 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTND---TEQAVI 70 + L+ G +P + W+GH P G + ND T QAV+ Sbjct: 105 ISLTGGAIVPGLYCSGWVGHGPVGVIATTMNDAYATGQAVV 145 >SB_50274| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 369 Score = 29.1 bits (62), Expect = 5.4 Identities = 14/55 (25%), Positives = 31/55 (56%) Query: 168 WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFK 222 W+ M DA++L L + S+ N++ + + S + P ++++ +Q PEL++ Sbjct: 11 WKPMPDAQELCLVELESDSSENKDVQRHFMSSMRQHPGKVKVQAISRVQNPELWE 65 >SB_16678| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 298 Score = 29.1 bits (62), Expect = 5.4 Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 154 ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQE-QIQRIIDSGLEKPSALQIELN 212 +N+ +DN DF T R M+ A+++ ++ SN N + QR+ P+AL ++ Sbjct: 80 DNERFVDNNDF--TSRKMLTAEEM--INAVFESNLNNRPENQRLYFRSSSMPTALHNDIC 135 Query: 213 LNLQQPELF 221 ++ Q ELF Sbjct: 136 IDSQMRELF 144 >SB_7780| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1309 Score = 29.1 bits (62), Expect = 5.4 Identities = 41/160 (25%), Positives = 66/160 (41%), Gaps = 10/160 (6%) Query: 15 RDLYEFLIPQSAELIVPTLQLSSGGNIPVVALGTWLGHR-PKGKV---VQVTNDTEQAVI 70 +++Y F Q+ +L VP ++ S+ N+ V L KGKV + ND +A Sbjct: 210 QEVYRFA--QTKKLNVPIVETSTYQNVNVDLAFVVLAQLIEKGKVRSRLVPYNDAHKAQQ 267 Query: 71 YALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPA-L 129 L+ + D R L K + L+ E F K N ++V + Sbjct: 268 EILDRALHDYQALINRTVTDF--RCLWKNLKKVLELEKEFTVYKELNGSDACKRVFSKHI 325 Query: 130 RKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFL-DTW 168 RK L +DLYL + P A+ E L ++D ++W Sbjct: 326 RKLRREFELRKLDLYLQNLPQALDELLPTLTSIDLCQNSW 365 Database: nematostella Posted date: Oct 22, 2007 1:22 PM Number of letters in database: 16,821,457 Number of sequences in database: 59,808 Lambda K H 0.319 0.138 0.407 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 11,547,289 Number of Sequences: 59808 Number of extensions: 460068 Number of successful extensions: 1343 Number of sequences better than 10.0: 17 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 1318 Number of HSP's gapped (non-prelim): 18 length of query: 340 length of database: 16,821,457 effective HSP length: 83 effective length of query: 257 effective length of database: 11,857,393 effective search space: 3047350001 effective search space used: 3047350001 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 60 (28.3 bits)
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