GeneModel BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001351-TA|BGIBMGA001351-PA|IPR001395|Aldo/keto reductase
         (340 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Z28339-1|CAA82193.1|  326|Homo sapiens delta 4-3-oxosteroid 5 be...   227   4e-59
BC130627-1|AAI30628.1|  326|Homo sapiens aldo-keto reductase fam...   227   4e-59
BC130625-1|AAI30626.1|  326|Homo sapiens aldo-keto reductase fam...   227   4e-59
AF283659-1|AAG39381.1|  326|Homo sapiens 5-beta steroid reductas...   227   4e-59
CR542203-1|CAG47000.1|  316|Homo sapiens AKR1B1 protein.              226   8e-59
X15414-1|CAA33460.1|  316|Homo sapiens protein ( Human mRNA for ...   224   3e-58
M59783-1|AAA51712.1|  316|Homo sapiens aldose reductase protein.      224   3e-58
M34720-1|AAA35560.1|  316|Homo sapiens protein ( Human aldose re...   224   3e-58
J05474-1|AAA51715.1|  316|Homo sapiens aldose reductase protein.      224   3e-58
J04795-1|AAA51713.1|  316|Homo sapiens ALDR1 protein.                 224   3e-58
BT019859-1|AAV38662.1|  316|Homo sapiens aldo-keto reductase fam...   224   3e-58
BC010391-1|AAH10391.1|  316|Homo sapiens aldo-keto reductase fam...   224   3e-58
BC000260-1|AAH00260.1|  316|Homo sapiens aldo-keto reductase fam...   224   3e-58
AF328729-1|AAN09721.1|  316|Homo sapiens CTCL tumor antigen HD-C...   224   3e-58
AF032455-1|AAB88851.1|  316|Homo sapiens aldose reductase protein.    224   3e-58
CR450351-1|CAG29347.1|  316|Homo sapiens AKR1B1 protein.              224   4e-58
J05017-1|AAA51714.1|  316|Homo sapiens ALDR1 protein.                 223   5e-58
BC020744-1|AAH20744.1|  323|Homo sapiens aldo-keto reductase fam...   223   9e-58
S68287-1|AAD14010.1|  323|Homo sapiens chlordecone reductase pro...   222   2e-57
D26125-1|BAA05122.1|  321|Homo sapiens 3 alpha-hydroxysteroid/di...   222   2e-57
AB045829-1|BAA99542.1|  323|Homo sapiens 3alpha-hydroxysteroid d...   222   2e-57
AB032163-1|BAA92893.1|  323|Homo sapiens dihydrodiol dehydrogena...   222   2e-57
AB031085-1|BAA92885.1|  323|Homo sapiens dihydrodiol dehydrogena...   222   2e-57
AL355303-2|CAI14202.1|  323|Homo sapiens aldo-keto reductase fam...   221   2e-57
U05861-1|AAA18115.1|  323|Homo sapiens hepatic dihydrodiol dehyd...   220   7e-57
U05684-1|AAA16227.1|  323|Homo sapiens dihydrodiol dehydrogenase...   220   7e-57
M86609-1|AAB02880.1|  323|Homo sapiens dihydrodiol dehydrogenase...   220   7e-57
BT007197-1|AAP35861.1|  323|Homo sapiens aldo-keto reductase fam...   220   7e-57
BC040210-1|AAH40210.1|  323|Homo sapiens aldo-keto reductase fam...   220   7e-57
BC020216-1|AAH20216.1|  323|Homo sapiens aldo-keto reductase fam...   220   7e-57
BC015490-1|AAH15490.1|  323|Homo sapiens aldo-keto reductase fam...   220   7e-57
AL713867-2|CAI16409.1|  323|Homo sapiens aldo-keto reductase fam...   220   7e-57
AB032150-1|BAA92886.1|  323|Homo sapiens 20 alph-hydroxysteroid ...   220   7e-57
AB031083-1|BAA92883.1|  323|Homo sapiens 20 alpha-hydroxysteroid...   220   7e-57
U37100-1|AAC17469.1|  316|Homo sapiens aldose reductase-like pep...   219   9e-57
U05598-1|AAA20937.1|  323|Homo sapiens dihydrodiol dehydrogenase...   219   9e-57
CR541801-1|CAG46600.1|  316|Homo sapiens AKR1B10 protein.             219   9e-57
BT006794-1|AAP35440.1|  316|Homo sapiens aldo-keto reductase fam...   219   9e-57
BT006653-1|AAP35299.1|  323|Homo sapiens aldo-keto reductase fam...   219   9e-57
BC063574-1|AAH63574.1|  323|Homo sapiens aldo-keto reductase fam...   219   9e-57
BC008837-1|AAH08837.1|  316|Homo sapiens aldo-keto reductase fam...   219   9e-57
BC007024-1|AAH07024.1|  323|Homo sapiens aldo-keto reductase fam...   219   9e-57
AL713867-1|CAI16408.1|  323|Homo sapiens aldo-keto reductase fam...   219   9e-57
AL391427-1|CAI14726.1|  323|Homo sapiens aldo-keto reductase fam...   219   9e-57
AF052577-1|AAC36465.1|  316|Homo sapiens aldo-keto reductase pro...   219   9e-57
AB032153-1|BAA92891.1|  323|Homo sapiens bile acid-binding prote...   219   9e-57
AB031084-1|BAA92884.1|  323|Homo sapiens bile acid-binding prote...   219   9e-57
AB021654-1|BAA36169.1|  323|Homo sapiens DD2/bile acid-binding p...   219   9e-57
D17793-1|BAA04619.2|  325|Homo sapiens KIAA0119 protein.              219   1e-56
BT007286-1|AAP35950.1|  323|Homo sapiens aldo-keto reductase fam...   219   1e-56
BC019230-1|AAH19230.1|  323|Homo sapiens aldo-keto reductase fam...   219   1e-56
BC001479-1|AAH01479.1|  323|Homo sapiens aldo-keto reductase fam...   219   1e-56
AL391427-4|CAI14729.1|  323|Homo sapiens aldo-keto reductase fam...   219   1e-56
AB032157-1|BAA92892.1|  323|Homo sapiens prostaglandin F synthas...   219   1e-56
AB018580-1|BAA88488.1|  323|Homo sapiens hluPGFS protein.             219   1e-56
BC005387-1|AAH05387.1|  316|Homo sapiens aldo-keto reductase fam...   219   2e-56
M33375-1|AAA35658.1|  308|Homo sapiens protein ( Human chlordeco...   218   2e-56
AF524864-1|AAO13380.1|  316|Homo sapiens aldo-ketoreductase prot...   218   3e-56
S68288-1|AAD14011.1|  323|Homo sapiens chlordecone reductase hom...   217   6e-56
L43839-1|AAB41916.1|  323|Homo sapiens 3-alpha-hydroxysteroid de...   216   1e-55
DQ269985-1|ABB76132.1|  323|Homo sapiens type II 3a-hydroxystero...   216   1e-55
S68330-1|AAD14013.1|  323|Homo sapiens chlordecone reductase hom...   215   1e-55
L32592-1|AAB38486.1|  323|Homo sapiens dihydrodiol dehydrogenase...   215   1e-55
AF149416-1|AAF07272.2|  323|Homo sapiens 3-alpha hydroxysteroid ...   214   3e-55
D26124-1|BAA05121.1|  306|Homo sapiens dihydrodiol dehydrogenase...   213   6e-55
S68290-1|AAD14012.1|  320|Homo sapiens chlordecone reductase hom...   212   1e-54
J04794-1|AAA51711.1|  325|Homo sapiens ALDR1 protein.                 204   3e-52
CR457010-1|CAG33291.1|  325|Homo sapiens AKR1A1 protein.              204   3e-52
BT007003-1|AAP35649.1|  325|Homo sapiens aldo-keto reductase fam...   204   3e-52
BC005394-1|AAH05394.1|  325|Homo sapiens aldo-keto reductase fam...   204   3e-52
BC000670-1|AAH00670.1|  325|Homo sapiens aldo-keto reductase fam...   204   3e-52
AL355480-3|CAI22459.1|  325|Homo sapiens aldo-keto reductase fam...   204   3e-52
AF112485-1|AAF01260.1|  325|Homo sapiens aldehyde reductase prot...   204   3e-52
AF036683-1|AAB92369.1|  325|Homo sapiens aldehyde reductase prot...   204   3e-52
AL391427-2|CAI14727.1|  302|Homo sapiens aldo-keto reductase fam...   173   7e-43
AL355303-1|CAI14201.1|  302|Homo sapiens aldo-keto reductase fam...   173   7e-43
AB209796-1|BAD93033.1|  260|Homo sapiens aldo-keto reductase fam...   173   7e-43
AB209017-1|BAD92254.1|  286|Homo sapiens aldo-keto reductase fam...   164   5e-40
AL713867-3|CAI16410.1|  247|Homo sapiens aldo-keto reductase fam...   162   1e-39
AF263242-1|AAK58523.1|  320|Homo sapiens aldo-keto reductase loo...   120   7e-27
BC002862-1|AAH02862.1|  307|Homo sapiens AKR1CL2 protein protein.     111   3e-24
AB055603-1|BAC54568.1|  307|Homo sapiens aldo-keto reductase rel...   111   3e-24
AL355480-2|CAI22458.1|  147|Homo sapiens aldo-keto reductase fam...   108   2e-23
BC101205-1|AAI01206.1|  129|Homo sapiens aldo-keto reductase fam...    97   6e-20
BC101204-1|AAI01205.1|  129|Homo sapiens aldo-keto reductase fam...    97   6e-20
AK131335-1|BAD18494.1|  129|Homo sapiens protein ( Homo sapiens ...    97   6e-20
AB040822-1|BAC54567.1|  222|Homo sapiens aldo-keto reductase rel...    95   4e-19
AB040821-1|BAC54566.1|  263|Homo sapiens aldo-keto reductase rel...    95   4e-19
AB040820-1|BAC54565.1|  250|Homo sapiens aldo-keto reductase rel...    95   4e-19
AB037902-1|BAA92887.1|  130|Homo sapiens truncated aldo-keto red...    90   9e-18
AK058142-1|BAB71682.1|  146|Homo sapiens protein ( Homo sapiens ...    74   8e-13
AF044961-1|AAC15671.1|   85|Homo sapiens aldose reductase-relate...    69   3e-11
U33429-1|AAC50955.1|  367|Homo sapiens K+ channel beta 2 subunit...    49   2e-05
CR542287-1|CAG47082.1|  353|Homo sapiens KCNAB2 protein.               49   2e-05
BC130413-1|AAI30414.1|  367|Homo sapiens potassium voltage-gated...    49   2e-05
BC126424-1|AAI26425.1|  367|Homo sapiens potassium voltage-gated...    49   2e-05
BC110351-1|AAI10352.1|  395|Homo sapiens KCNAB2 protein protein.       49   2e-05
AL035406-6|CAI19886.1|  253|Homo sapiens potassium voltage-gated...    49   2e-05
AL035406-5|CAI19887.1|  254|Homo sapiens potassium voltage-gated...    49   2e-05
AL035406-4|CAC08512.1|  367|Homo sapiens potassium voltage-gated...    49   2e-05
AL035406-3|CAI19885.1|  353|Homo sapiens potassium voltage-gated...    49   2e-05
AK131252-1|BAD18431.1|  415|Homo sapiens protein ( Homo sapiens ...    49   2e-05
AF044253-1|AAB99859.1|  353|Homo sapiens potassium channel beta ...    49   2e-05
AF029749-1|AAB84170.1|  367|Homo sapiens potassium channel beta ...    49   2e-05
X83127-1|CAA58208.1|  401|Homo sapiens voltage gated potassium c...    48   5e-05
U33428-1|AAC50953.1|  401|Homo sapiens K+ channel beta 1a subuni...    48   5e-05
U16953-1|AAC50122.1|  408|Homo sapiens potassium channel beta3 s...    48   5e-05
L47665-1|AAC41926.1|  419|Homo sapiens K+ channel beta-subunit p...    48   5e-05
L39833-1|AAC37573.1|  408|Homo sapiens K+ channel beta-subunit p...    48   5e-05
BC043166-1|AAH43166.1|  401|Homo sapiens potassium voltage-gated...    48   5e-05
CR542264-1|CAG47060.1|  353|Homo sapiens KCNAB2 protein.               47   1e-04
AB028065-1|BAA88489.1|   67|Homo sapiens prostaglandin F synthas...    46   2e-04
BC099634-1|AAH99634.1|  404|Homo sapiens potassium voltage-gated...    46   3e-04
BC096234-1|AAH96234.1|  404|Homo sapiens potassium voltage-gated...    46   3e-04
BC096232-1|AAH96232.1|  404|Homo sapiens potassium voltage-gated...    46   3e-04
AF016411-1|AAB92499.1|  404|Homo sapiens KCNA3.1B protein.             44   6e-04
AB037905-2|BAA92890.1|   45|Homo sapiens truncated aldo-keto red...    38   0.051
AF026947-1|AAC52104.1|  330|Homo sapiens aflatoxin aldehyde redu...    36   0.27 
Y16675-1|CAA76347.1|  330|Homo sapiens aflatoxin B1-aldehyde red...    35   0.36 
BT007347-1|AAP36011.1|  330|Homo sapiens aldo-keto reductase fam...    35   0.36 
BC013996-1|AAH13996.1|  330|Homo sapiens AKR7A2 protein protein.       35   0.36 
BC012171-1|AAH12171.1|  330|Homo sapiens AKR7A2 protein protein.       35   0.36 
BC011586-1|AAH11586.1|  330|Homo sapiens AKR7A2 protein protein.       35   0.36 
BC010852-1|AAH10852.1|  330|Homo sapiens AKR7A2 protein protein.       35   0.36 
BC007352-1|AAH07352.2|  358|Homo sapiens AKR7A2 protein protein.       35   0.36 
BC004111-1|AAH04111.3|  330|Homo sapiens AKR7A2 protein protein.       35   0.36 
AL035413-8|CAB72321.1|  330|Homo sapiens aldo-keto reductase fam...    35   0.36 
D83174-1|BAA11829.1|  418|Homo sapiens collagen binding protein ...    35   0.48 
AY780786-1|AAV98356.1|  372|Homo sapiens potassium voltage-gated...    34   0.63 
BC075018-1|AAH75018.1|  599|Homo sapiens DEAQ box polypeptide 1 ...    34   0.83 
BC070087-1|AAH70087.1|  418|Homo sapiens serpin peptidase inhibi...    34   0.83 
AK074337-1|BAB85056.1|  599|Homo sapiens protein ( Homo sapiens ...    34   0.83 
X61598-1|CAA43795.1|  417|Homo sapiens colligin protein.               33   1.5  
BT007094-1|AAP35758.1|  418|Homo sapiens serine (or cysteine) pr...    32   2.5  
BC036298-1|AAH36298.2|  418|Homo sapiens serpin peptidase inhibi...    32   2.5  
BC014623-1|AAH14623.1|  418|Homo sapiens serpin peptidase inhibi...    32   2.5  
AY744367-1|AAU95378.1|  418|Homo sapiens arsenic-transactivated ...    32   2.5  
AY264853-1|AAP93914.1|  418|Homo sapiens proliferation-inducing ...    32   2.5  
AB044779-1|BAA96789.1|  418|Homo sapiens rheumatoid arthritis re...    32   2.5  
AB044778-1|BAA96788.1|  418|Homo sapiens rheumatoid arthritis re...    32   2.5  
M64590-1|AAA36463.1| 1020|Homo sapiens glycine decarboxylase pro...    31   5.9  
M63635-1|AAA36478.1| 1020|Homo sapiens glycine decarboxylase pro...    31   5.9  
D90239-1|BAA14286.1| 1020|Homo sapiens glycine decarboxylase pre...    31   5.9  
BC111995-1|AAI11996.1| 1020|Homo sapiens glycine dehydrogenase (...    31   5.9  
BC111993-1|AAI11994.1| 1020|Homo sapiens glycine dehydrogenase (...    31   5.9  
AL353718-2|CAH74116.1| 1036|Homo sapiens glycine dehydrogenase (...    31   5.9  
AL162411-3|CAH69992.1| 1036|Homo sapiens glycine dehydrogenase (...    31   5.9  
AF246134-1|AAK28443.2|  331|Homo sapiens glycine decarboxylase P...    31   5.9  
BC042420-1|AAH42420.2|  331|Homo sapiens aldo-keto reductase fam...    31   7.7  
BC031562-1|AAH31562.1|  331|Homo sapiens aldo-keto reductase fam...    31   7.7  
AJ271799-1|CAC81076.1|  331|Homo sapiens aflatoxin B1 aldehyde r...    31   7.7  
AF040639-1|AAD02195.1|  331|Homo sapiens aflatoxin B1-aldehyde r...    31   7.7  

>Z28339-1|CAA82193.1|  326|Homo sapiens delta 4-3-oxosteroid 5
           beta-reductase protein.
          Length = 326

 Score =  227 bits (555), Expect = 4e-59
 Identities = 127/318 (39%), Positives = 187/318 (58%), Gaps = 18/318 (5%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           + LS G +IP++ LGT+   +   K    T+     V  A++ GY HID AY Y  E +V
Sbjct: 10  IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64

Query: 93  GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K +EG ++RE IF   KLW + H  E V P L ++L  L L+YVDLY+I  P+A
Sbjct: 65  GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124

Query: 152 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
               D +    +N  +L        TW  M   K  GL KS+G+SNFN+ Q++ I++  G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP + Q+E +    QP+L KFC+++DIV+ AY+P G+         + PP + D  L
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            S+ ++YNKT  Q+ LRF I+ G VV+PKS + ERI++N Q+FDFSLT EE   +++ + 
Sbjct: 245 NSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNK 304

Query: 320 GYRTLPQTKWSKHPDYPF 337
             R +    W  HP+YPF
Sbjct: 305 NVRFVELLMWRDHPEYPF 322


>BC130627-1|AAI30628.1|  326|Homo sapiens aldo-keto reductase family
           1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
           protein.
          Length = 326

 Score =  227 bits (555), Expect = 4e-59
 Identities = 127/318 (39%), Positives = 187/318 (58%), Gaps = 18/318 (5%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           + LS G +IP++ LGT+   +   K    T+     V  A++ GY HID AY Y  E +V
Sbjct: 10  IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64

Query: 93  GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K +EG ++RE IF   KLW + H  E V P L ++L  L L+YVDLY+I  P+A
Sbjct: 65  GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124

Query: 152 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
               D +    +N  +L        TW  M   K  GL KS+G+SNFN+ Q++ I++  G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP + Q+E +    QP+L KFC+++DIV+ AY+P G+         + PP + D  L
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            S+ ++YNKT  Q+ LRF I+ G VV+PKS + ERI++N Q+FDFSLT EE   +++ + 
Sbjct: 245 NSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNK 304

Query: 320 GYRTLPQTKWSKHPDYPF 337
             R +    W  HP+YPF
Sbjct: 305 NVRFVELLMWRDHPEYPF 322


>BC130625-1|AAI30626.1|  326|Homo sapiens aldo-keto reductase family
           1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
           protein.
          Length = 326

 Score =  227 bits (555), Expect = 4e-59
 Identities = 127/318 (39%), Positives = 187/318 (58%), Gaps = 18/318 (5%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           + LS G +IP++ LGT+   +   K    T+     V  A++ GY HID AY Y  E +V
Sbjct: 10  IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64

Query: 93  GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K +EG ++RE IF   KLW + H  E V P L ++L  L L+YVDLY+I  P+A
Sbjct: 65  GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124

Query: 152 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
               D +    +N  +L        TW  M   K  GL KS+G+SNFN+ Q++ I++  G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP + Q+E +    QP+L KFC+++DIV+ AY+P G+         + PP + D  L
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            S+ ++YNKT  Q+ LRF I+ G VV+PKS + ERI++N Q+FDFSLT EE   +++ + 
Sbjct: 245 NSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNK 304

Query: 320 GYRTLPQTKWSKHPDYPF 337
             R +    W  HP+YPF
Sbjct: 305 NVRFVELLMWRDHPEYPF 322


>AF283659-1|AAG39381.1|  326|Homo sapiens 5-beta steroid reductase
           protein.
          Length = 326

 Score =  227 bits (555), Expect = 4e-59
 Identities = 127/318 (39%), Positives = 187/318 (58%), Gaps = 18/318 (5%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           + LS G +IP++ LGT+   +   K    T+     V  A++ GY HID AY Y  E +V
Sbjct: 10  IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64

Query: 93  GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K +EG ++RE IF   KLW + H  E V P L ++L  L L+YVDLY+I  P+A
Sbjct: 65  GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124

Query: 152 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
               D +    +N  +L        TW  M   K  GL KS+G+SNFN+ Q++ I++  G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP + Q+E +    QP+L KFC+++DIV+ AY+P G+         + PP + D  L
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            S+ ++YNKT  Q+ LRF I+ G VV+PKS + ERI++N Q+FDFSLT EE   +++ + 
Sbjct: 245 NSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNK 304

Query: 320 GYRTLPQTKWSKHPDYPF 337
             R +    W  HP+YPF
Sbjct: 305 NVRFVELLMWRDHPEYPF 322


>CR542203-1|CAG47000.1|  316|Homo sapiens AKR1B1 protein.
          Length = 316

 Score =  226 bits (553), Expect = 8e-59
 Identities = 129/318 (40%), Positives = 191/318 (60%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWPI 
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>X15414-1|CAA33460.1|  316|Homo sapiens protein ( Human mRNA for
           aldose reductase (EC 1.1.1.2). ).
          Length = 316

 Score =  224 bits (548), Expect = 3e-58
 Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>M59783-1|AAA51712.1|  316|Homo sapiens aldose reductase protein.
          Length = 316

 Score =  224 bits (548), Expect = 3e-58
 Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>M34720-1|AAA35560.1|  316|Homo sapiens protein ( Human aldose
           reductase mRNA, complete cds. ).
          Length = 316

 Score =  224 bits (548), Expect = 3e-58
 Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>J05474-1|AAA51715.1|  316|Homo sapiens aldose reductase protein.
          Length = 316

 Score =  224 bits (548), Expect = 3e-58
 Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>J04795-1|AAA51713.1|  316|Homo sapiens ALDR1 protein.
          Length = 316

 Score =  224 bits (548), Expect = 3e-58
 Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>BT019859-1|AAV38662.1|  316|Homo sapiens aldo-keto reductase family
           1, member B1 (aldose reductase) protein.
          Length = 316

 Score =  224 bits (548), Expect = 3e-58
 Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>BC010391-1|AAH10391.1|  316|Homo sapiens aldo-keto reductase family
           1, member B1 (aldose reductase) protein.
          Length = 316

 Score =  224 bits (548), Expect = 3e-58
 Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>BC000260-1|AAH00260.1|  316|Homo sapiens aldo-keto reductase family
           1, member B1 (aldose reductase) protein.
          Length = 316

 Score =  224 bits (548), Expect = 3e-58
 Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>AF328729-1|AAN09721.1|  316|Homo sapiens CTCL tumor antigen
           HD-CL-07 protein.
          Length = 316

 Score =  224 bits (548), Expect = 3e-58
 Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>AF032455-1|AAB88851.1|  316|Homo sapiens aldose reductase protein.
          Length = 316

 Score =  224 bits (548), Expect = 3e-58
 Identities = 128/318 (40%), Positives = 190/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>CR450351-1|CAG29347.1|  316|Homo sapiens AKR1B1 protein.
          Length = 316

 Score =  224 bits (547), Expect = 4e-58
 Identities = 128/318 (40%), Positives = 189/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I+   G
Sbjct: 116 FRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>J05017-1|AAA51714.1|  316|Homo sapiens ALDR1 protein.
          Length = 316

 Score =  223 bits (546), Expect = 5e-58
 Identities = 127/316 (40%), Positives = 189/316 (59%), Gaps = 23/316 (7%)

Query: 35  LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
           L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++VG 
Sbjct: 7   LNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGV 57

Query: 95  ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM- 152
           A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP    
Sbjct: 58  AIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117

Query: 153 -----FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE 202
                F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  GL+
Sbjct: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177

Query: 203 -KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVS 261
            KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+ +
Sbjct: 178 YKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRIKA 236

Query: 262 IAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGY 321
           IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++  +
Sbjct: 237 IAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296

Query: 322 RTLPQTKWSKHPDYPF 337
           R       + H DYPF
Sbjct: 297 RVCALLSCTSHKDYPF 312


>BC020744-1|AAH20744.1|  323|Homo sapiens aldo-keto reductase family
           1, member C4 (chlordecone reductase; 3-alpha hydroxy
           protein.
          Length = 323

 Score =  223 bits (544), Expect = 9e-58
 Identities = 123/319 (38%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ + V+VT         A+EAG+ HID+AY Y  E+Q
Sbjct: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW ++ + + V PAL  SL+ L L+YVDLYL+H+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120

Query: 151 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           A+   +T          + D VD   TW  M   K  GL KSIG+SNFN  Q++ I++  
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +  L Q +L  FC+  DIV++A++  G+           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI +NIQ+F+F LT E+  +L   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
             YR +       HPDYPF
Sbjct: 301 RNYRYVVMDFLMDHPDYPF 319


>S68287-1|AAD14010.1|  323|Homo sapiens chlordecone reductase
           protein.
          Length = 323

 Score =  222 bits (542), Expect = 2e-57
 Identities = 123/319 (38%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ + V+VT         A+EAG+ HID+AY Y  E+Q
Sbjct: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW ++ + + V PAL  SL+ L L+YVDLYL+H+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120

Query: 151 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           A+   +T          + D VD   TW  M   K  GL KSIG+SNFN  Q++ I++  
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +  L Q +L  FC+  DIV++A++  G+           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI +NIQ+F+F LT E+  +L   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
             YR +       HPDYPF
Sbjct: 301 RNYRYVVMDFLMDHPDYPF 319


>D26125-1|BAA05122.1|  321|Homo sapiens 3
           alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
           protein.
          Length = 321

 Score =  222 bits (542), Expect = 2e-57
 Identities = 123/319 (38%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ + V+VT         A+EAG+ HID+AY Y  E+Q
Sbjct: 6   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 58

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW ++ + + V PAL  SL+ L L+YVDLYL+H+P+
Sbjct: 59  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 118

Query: 151 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           A+   +T          + D VD   TW  M   K  GL KSIG+SNFN  Q++ I++  
Sbjct: 119 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 178

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +  L Q +L  FC+  DIV++A++  G+           P  ++D  
Sbjct: 179 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 238

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI +NIQ+F+F LT E+  +L   +
Sbjct: 239 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 298

Query: 319 TGYRTLPQTKWSKHPDYPF 337
             YR +       HPDYPF
Sbjct: 299 RNYRYVVMDFLMDHPDYPF 317


>AB045829-1|BAA99542.1|  323|Homo sapiens 3alpha-hydroxysteroid
           dehydrogenase variant protein.
          Length = 323

 Score =  222 bits (542), Expect = 2e-57
 Identities = 123/319 (38%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ + V+VT         A+EAG+ HID+AY Y  E+Q
Sbjct: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW ++ + + V PAL  SL+ L L+YVDLYL+H+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120

Query: 151 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           A+   +T          + D VD   TW  M   K  GL KSIG+SNFN  Q++ I++  
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +  L Q +L  FC+  DIV++A++  G+           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI +NIQ+F+F LT E+  +L   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
             YR +       HPDYPF
Sbjct: 301 RNYRYVVMDFVMDHPDYPF 319


>AB032163-1|BAA92893.1|  323|Homo sapiens dihydrodiol dehydrogenase
           4 protein.
          Length = 323

 Score =  222 bits (542), Expect = 2e-57
 Identities = 123/319 (38%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ + V+VT         A+EAG+ HID+AY Y  E+Q
Sbjct: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW ++ + + V PAL  SL+ L L+YVDLYL+H+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120

Query: 151 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           A+   +T          + D VD   TW  M   K  GL KSIG+SNFN  Q++ I++  
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +  L Q +L  FC+  DIV++A++  G+           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI +NIQ+F+F LT E+  +L   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
             YR +       HPDYPF
Sbjct: 301 RNYRYVVMDFLMDHPDYPF 319


>AB031085-1|BAA92885.1|  323|Homo sapiens dihydrodiol dehydrogenase
           4 protein.
          Length = 323

 Score =  222 bits (542), Expect = 2e-57
 Identities = 123/319 (38%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ + V+VT         A+EAG+ HID+AY Y  E+Q
Sbjct: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW ++ + + V PAL  SL+ L L+YVDLYL+H+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120

Query: 151 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           A+   +T          + D VD   TW  M   K  GL KSIG+SNFN  Q++ I++  
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +  L Q +L  FC+  DIV++A++  G+           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI +NIQ+F+F LT E+  +L   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
             YR +       HPDYPF
Sbjct: 301 RNYRYVVMDFLMDHPDYPF 319


>AL355303-2|CAI14202.1|  323|Homo sapiens aldo-keto reductase family
           1, member C4 (chlordecone reductase; 3-alpha hydroxy
           protein.
          Length = 323

 Score =  221 bits (541), Expect = 2e-57
 Identities = 123/319 (38%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ + V+VT         A+EAG+ HID+AY Y  E+Q
Sbjct: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW ++ + + V PAL  SL+ L L+YVDLYL+H+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120

Query: 151 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           A+   +T          + D VD   TW  M   K  GL KSIG+SNFN  Q++ I++  
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +  L Q +L  FC+  DIV++A++  G+           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI +NIQ+F+F LT E+  +L   +
Sbjct: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
             YR +       HPDYPF
Sbjct: 301 RNYRYVVMDFLMDHPDYPF 319


>U05861-1|AAA18115.1|  323|Homo sapiens hepatic dihydrodiol
           dehydrogenase protein.
          Length = 323

 Score =  220 bits (537), Expect = 7e-57
 Identities = 125/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>U05684-1|AAA16227.1|  323|Homo sapiens dihydrodiol dehydrogenase
           protein.
          Length = 323

 Score =  220 bits (537), Expect = 7e-57
 Identities = 125/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>M86609-1|AAB02880.1|  323|Homo sapiens dihydrodiol dehydrogenase
           protein.
          Length = 323

 Score =  220 bits (537), Expect = 7e-57
 Identities = 125/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>BT007197-1|AAP35861.1|  323|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 323

 Score =  220 bits (537), Expect = 7e-57
 Identities = 125/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>BC040210-1|AAH40210.1|  323|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 323

 Score =  220 bits (537), Expect = 7e-57
 Identities = 125/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>BC020216-1|AAH20216.1|  323|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 323

 Score =  220 bits (537), Expect = 7e-57
 Identities = 125/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>BC015490-1|AAH15490.1|  323|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 323

 Score =  220 bits (537), Expect = 7e-57
 Identities = 125/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>AL713867-2|CAI16409.1|  323|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 323

 Score =  220 bits (537), Expect = 7e-57
 Identities = 125/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>AB032150-1|BAA92886.1|  323|Homo sapiens 20 alph-hydroxysteroid
           dehydrogenase protein.
          Length = 323

 Score =  220 bits (537), Expect = 7e-57
 Identities = 125/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>AB031083-1|BAA92883.1|  323|Homo sapiens 20 alpha-hydroxysteroid
           dehydrogenase protein.
          Length = 323

 Score =  220 bits (537), Expect = 7e-57
 Identities = 125/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>U37100-1|AAC17469.1|  316|Homo sapiens aldose reductase-like
           peptide protein.
          Length = 316

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/318 (39%), Positives = 183/318 (57%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           ++LS+   +P+V LGTW    P GKV       ++AV  A++AGY HID AY Y  E +V
Sbjct: 5   VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 93  GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E  +KRE +FI +KLW ++ ER  V  A  K+L++L L Y+D+YLIHWP  
Sbjct: 56  GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115

Query: 152 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
               D L    D          FLD W  M +    GL K++G+SNF+  QI+++++  G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP   Q+E +  L Q +L ++C    I V AY+P GS     A+P+  P  ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPE-DPSLLEDPKI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
             IA K+ KT  QV +RF I+   +V+PKSV   RI +NIQ+FDF L+ EE   + SF+ 
Sbjct: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R     + S   DYPF
Sbjct: 295 NWRACNVLQSSHLEDYPF 312


>U05598-1|AAA20937.1|  323|Homo sapiens dihydrodiol dehydrogenase
           protein.
          Length = 323

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>CR541801-1|CAG46600.1|  316|Homo sapiens AKR1B10 protein.
          Length = 316

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/318 (39%), Positives = 183/318 (57%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           ++LS+   +P+V LGTW    P GKV       ++AV  A++AGY HID AY Y  E +V
Sbjct: 5   VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 93  GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E  +KRE +FI +KLW ++ ER  V  A  K+L++L L Y+D+YLIHWP  
Sbjct: 56  GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115

Query: 152 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
               D L    D          FLD W  M +    GL K++G+SNF+  QI+++++  G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP   Q+E +  L Q +L ++C    I V AY+P GS     A+P+  P  ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPE-DPSLLEDPKI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
             IA K+ KT  QV +RF I+   +V+PKSV   RI +NIQ+FDF L+ EE   + SF+ 
Sbjct: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R     + S   DYPF
Sbjct: 295 NWRACNVLQSSHLEDYPF 312


>BT006794-1|AAP35440.1|  316|Homo sapiens aldo-keto reductase family
           1, member B10 (aldose reductase) protein.
          Length = 316

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/318 (39%), Positives = 183/318 (57%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           ++LS+   +P+V LGTW    P GKV       ++AV  A++AGY HID AY Y  E +V
Sbjct: 5   VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 93  GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E  +KRE +FI +KLW ++ ER  V  A  K+L++L L Y+D+YLIHWP  
Sbjct: 56  GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115

Query: 152 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
               D L    D          FLD W  M +    GL K++G+SNF+  QI+++++  G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP   Q+E +  L Q +L ++C    I V AY+P GS     A+P+  P  ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPE-DPSLLEDPKI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
             IA K+ KT  QV +RF I+   +V+PKSV   RI +NIQ+FDF L+ EE   + SF+ 
Sbjct: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R     + S   DYPF
Sbjct: 295 NWRACNVLQSSHLEDYPF 312


>BT006653-1|AAP35299.1|  323|Homo sapiens aldo-keto reductase family
           1, member C2 (dihydrodiol dehydrogenase 2; bile acid
           protein.
          Length = 323

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>BC063574-1|AAH63574.1|  323|Homo sapiens aldo-keto reductase family
           1, member C2 (dihydrodiol dehydrogenase 2; bile acid
           protein.
          Length = 323

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>BC008837-1|AAH08837.1|  316|Homo sapiens aldo-keto reductase family
           1, member B10 (aldose reductase) protein.
          Length = 316

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/318 (39%), Positives = 183/318 (57%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           ++LS+   +P+V LGTW    P GKV       ++AV  A++AGY HID AY Y  E +V
Sbjct: 5   VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 93  GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E  +KRE +FI +KLW ++ ER  V  A  K+L++L L Y+D+YLIHWP  
Sbjct: 56  GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115

Query: 152 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
               D L    D          FLD W  M +    GL K++G+SNF+  QI+++++  G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP   Q+E +  L Q +L ++C    I V AY+P GS     A+P+  P  ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPE-DPSLLEDPKI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
             IA K+ KT  QV +RF I+   +V+PKSV   RI +NIQ+FDF L+ EE   + SF+ 
Sbjct: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R     + S   DYPF
Sbjct: 295 NWRACNVLQSSHLEDYPF 312


>BC007024-1|AAH07024.1|  323|Homo sapiens aldo-keto reductase family
           1, member C2 (dihydrodiol dehydrogenase 2; bile acid
           protein.
          Length = 323

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>AL713867-1|CAI16408.1|  323|Homo sapiens aldo-keto reductase family
           1, member C2 (dihydrodiol dehydrogenase 2; bile acid
           protein.
          Length = 323

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>AL391427-1|CAI14726.1|  323|Homo sapiens aldo-keto reductase family
           1, member C2 (dihydrodiol dehydrogenase 2; bile acid
           protein.
          Length = 323

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>AF052577-1|AAC36465.1|  316|Homo sapiens aldo-keto reductase
           protein.
          Length = 316

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/318 (39%), Positives = 183/318 (57%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           ++LS+   +P+V LGTW    P GKV       ++AV  A++AGY HID AY Y  E +V
Sbjct: 5   VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 93  GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E  +KRE +FI +KLW ++ ER  V  A  K+L++L L Y+D+YLIHWP  
Sbjct: 56  GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115

Query: 152 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
               D L    D          FLD W  M +    GL K++G+SNF+  QI+++++  G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP   Q+E +  L Q +L ++C    I V AY+P GS     A+P+  P  ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPE-DPSLLEDPKI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
             IA K+ KT  QV +RF I+   +V+PKSV   RI +NIQ+FDF L+ EE   + SF+ 
Sbjct: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R     + S   DYPF
Sbjct: 295 NWRACNVLQSSHLEDYPF 312


>AB032153-1|BAA92891.1|  323|Homo sapiens bile acid-binding protein
           protein.
          Length = 323

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>AB031084-1|BAA92884.1|  323|Homo sapiens bile acid-binding protein
           protein.
          Length = 323

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>AB021654-1|BAA36169.1|  323|Homo sapiens DD2/bile acid-binding
           protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
           3 protein.
          Length = 323

 Score =  219 bits (536), Expect = 9e-57
 Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
              R L    ++  P+YPF
Sbjct: 301 RNVRYLTLDIFAGPPNYPF 319


>D17793-1|BAA04619.2|  325|Homo sapiens KIAA0119 protein.
          Length = 325

 Score =  219 bits (535), Expect = 1e-56
 Identities = 119/319 (37%), Positives = 186/319 (58%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ K ++VT         A+EAG+ HID+A+ Y  E+Q
Sbjct: 10  VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 62

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW+++H  E V PAL  SL+   L+YVDLYLIH P+
Sbjct: 63  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 122

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 123 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 182

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 183 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 242

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT E+   +   D
Sbjct: 243 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 302

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 303 RNLHYFNSDSFASHPNYPY 321


>BT007286-1|AAP35950.1|  323|Homo sapiens aldo-keto reductase family
           1, member C3 (3-alpha hydroxysteroid dehydrogenase,
           protein.
          Length = 323

 Score =  219 bits (535), Expect = 1e-56
 Identities = 119/319 (37%), Positives = 186/319 (58%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ K ++VT         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW+++H  E V PAL  SL+   L+YVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT E+   +   D
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 301 RNLHYFNSDSFASHPNYPY 319


>BC019230-1|AAH19230.1|  323|Homo sapiens aldo-keto reductase family
           1, member C3 (3-alpha hydroxysteroid dehydrogenase,
           protein.
          Length = 323

 Score =  219 bits (535), Expect = 1e-56
 Identities = 119/319 (37%), Positives = 186/319 (58%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ K ++VT         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW+++H  E V PAL  SL+   L+YVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT E+   +   D
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 301 RNLHYFNSDSFASHPNYPY 319


>BC001479-1|AAH01479.1|  323|Homo sapiens aldo-keto reductase family
           1, member C3 (3-alpha hydroxysteroid dehydrogenase,
           protein.
          Length = 323

 Score =  219 bits (535), Expect = 1e-56
 Identities = 119/319 (37%), Positives = 186/319 (58%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ K ++VT         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW+++H  E V PAL  SL+   L+YVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT E+   +   D
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 301 RNLHYFNSDSFASHPNYPY 319


>AL391427-4|CAI14729.1|  323|Homo sapiens aldo-keto reductase family
           1, member C3 (3-alpha hydroxysteroid dehydrogenase,
           protein.
          Length = 323

 Score =  219 bits (535), Expect = 1e-56
 Identities = 119/319 (37%), Positives = 186/319 (58%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ K ++VT         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW+++H  E V PAL  SL+   L+YVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT E+   +   D
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 301 RNLHYFNSDSFASHPNYPY 319


>AB032157-1|BAA92892.1|  323|Homo sapiens prostaglandin F synthase
           protein.
          Length = 323

 Score =  219 bits (535), Expect = 1e-56
 Identities = 119/319 (37%), Positives = 186/319 (58%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ K ++VT         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW+++H  E V PAL  SL+   L+YVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT E+   +   D
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 301 RNLHYFNSDSFASHPNYPY 319


>AB018580-1|BAA88488.1|  323|Homo sapiens hluPGFS protein.
          Length = 323

 Score =  219 bits (535), Expect = 1e-56
 Identities = 119/319 (37%), Positives = 186/319 (58%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ K ++VT         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW+++H  E V PAL  SL+   L+YVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT E+   +   D
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 301 RNLHYFNSDSFASHPNYPY 319


>BC005387-1|AAH05387.1|  316|Homo sapiens aldo-keto reductase family
           1, member B1 (aldose reductase) protein.
          Length = 316

 Score =  219 bits (534), Expect = 2e-56
 Identities = 127/318 (39%), Positives = 189/318 (59%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 5   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 56  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115

Query: 152 M------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDT   M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
            +IA K+NKT  QV +RF ++   VV+PKSV  ERI +N ++FDF L+ ++   L S++ 
Sbjct: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R       + H DYPF
Sbjct: 295 NWRVCALLSCTSHKDYPF 312


>M33375-1|AAA35658.1|  308|Homo sapiens protein ( Human chlordecone
           reductase mRNA, complete cds. ).
          Length = 308

 Score =  218 bits (533), Expect = 2e-56
 Identities = 121/311 (38%), Positives = 184/311 (59%), Gaps = 21/311 (6%)

Query: 41  IPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 99
           +PV+  GT+     P+ + V+VT         A+EAG+ HID+AY Y  E+QVG A+  K
Sbjct: 1   MPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAIRSK 53

Query: 100 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDT- 157
            ++G +KRE IF T+KLW ++ + + V PAL  SL+ L L+YVDLYL+H+P+A+   +T 
Sbjct: 54  IADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETP 113

Query: 158 ---------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSA 206
                    + D VD   TW  M   K  GL KSIG+SNFN  Q++ I++  GL+ KP  
Sbjct: 114 LPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVC 173

Query: 207 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKY 266
            Q+E +  L Q +L  FC+  DIV++A++  G+           P  ++D  L ++A+K+
Sbjct: 174 NQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKH 233

Query: 267 NKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQ 326
            +T   +ALR+ ++ G VVL KS +++RI +NIQ+F+F LT E+  +L   +  YR +  
Sbjct: 234 KRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVM 293

Query: 327 TKWSKHPDYPF 337
                HPDYPF
Sbjct: 294 DFLMDHPDYPF 304


>AF524864-1|AAO13380.1|  316|Homo sapiens aldo-ketoreductase
           protein.
          Length = 316

 Score =  218 bits (532), Expect = 3e-56
 Identities = 125/318 (39%), Positives = 183/318 (57%), Gaps = 23/318 (7%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           ++LS+   +P+V LGTW    P GKV       ++AV  A++AGY HID AY Y  E +V
Sbjct: 5   VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55

Query: 93  GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E  +KRE +FI +KLW ++ ER  V  A  K+L++  L Y+D+YLIHWP  
Sbjct: 56  GEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQG 115

Query: 152 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
               D L    D          FLD W  M +    GL K++G+SNF+  QI+++++  G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP   Q+E +  L Q +L ++C    I V AY+P GS     A+P+  P  ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPE-DPSLLEDPKI 234

Query: 260 VSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDT 319
             IA K+ KT  QV +RF I+   +V+PKSV   RI +NIQ+FDF L+ EE  ++ SF+ 
Sbjct: 235 KEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAIILSFNR 294

Query: 320 GYRTLPQTKWSKHPDYPF 337
            +R     + S   DYPF
Sbjct: 295 NWRACNVLQSSHLEDYPF 312


>S68288-1|AAD14011.1|  323|Homo sapiens chlordecone reductase
           homolog protein.
          Length = 323

 Score =  217 bits (529), Expect = 6e-56
 Identities = 118/319 (36%), Positives = 186/319 (58%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ K ++VT         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G ++RE IF T+KLW+++H  E V PAL  SL+   L+YVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT E+   +   D
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 301 RNLHYFNSDSFASHPNYPY 319


>L43839-1|AAB41916.1|  323|Homo sapiens 3-alpha-hydroxysteroid
           dehydrogenase protein.
          Length = 323

 Score =  216 bits (527), Expect = 1e-55
 Identities = 118/319 (36%), Positives = 185/319 (57%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ K ++VT         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G + RE IF T+KLW+++H  E V PAL  SL+   L+YVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT E+   +   D
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 301 RNLHYFNSDSFASHPNYPY 319


>DQ269985-1|ABB76132.1|  323|Homo sapiens type II 3a-hydroxysteroid
           dehydrogenase variant protein.
          Length = 323

 Score =  216 bits (527), Expect = 1e-55
 Identities = 119/319 (37%), Positives = 184/319 (57%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+   L+YVDLYLIH P+
Sbjct: 61  VGLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPM 120

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT E+   +   D
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 301 RNLHYFNSDSFASHPNYPY 319


>S68330-1|AAD14013.1|  323|Homo sapiens chlordecone reductase
           homolog protein.
          Length = 323

 Score =  215 bits (526), Expect = 1e-55
 Identities = 124/318 (38%), Positives = 188/318 (59%), Gaps = 21/318 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 151 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-DS 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I+ + 
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ +P   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYP 336
              R L    ++  P+YP
Sbjct: 301 RNVRYLTLDIFAGPPNYP 318


>L32592-1|AAB38486.1|  323|Homo sapiens dihydrodiol
           dehydrogenase/bile acid-binding protein protein.
          Length = 323

 Score =  215 bits (526), Expect = 1e-55
 Identities = 124/318 (38%), Positives = 187/318 (58%), Gaps = 21/318 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAGY HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGYHHIDSAHVYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+Y DLYLIH+P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPV 120

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ +P   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 181 GLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 319 TGYRTLPQTKWSKHPDYP 336
              R L    ++  P+YP
Sbjct: 301 RNVRYLTLDIFAGPPNYP 318


>AF149416-1|AAF07272.2|  323|Homo sapiens 3-alpha hydroxysteroid
           dehydrogenase type IIb protein.
          Length = 323

 Score =  214 bits (523), Expect = 3e-55
 Identities = 117/319 (36%), Positives = 185/319 (57%), Gaps = 21/319 (6%)

Query: 33  LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     P+ K ++V+         A+EAG+ HID+A+ Y  E+Q
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSK-------LAIEAGFRHIDSAHLYNNEEQ 60

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL  SL+   L+YVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 151 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++   + L           D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    + +L  FC+  DIV++AY+  GS    +      P  ++D  
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL +S +++RI QN+Q+F+F LT E+   +   D
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLARSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 319 TGYRTLPQTKWSKHPDYPF 337
                     ++ HP+YP+
Sbjct: 301 RNLHYFNSDSFASHPNYPY 319


>D26124-1|BAA05121.1|  306|Homo sapiens dihydrodiol dehydrogenase
           isoform DD1 protein.
          Length = 306

 Score =  213 bits (521), Expect = 6e-55
 Identities = 122/309 (39%), Positives = 182/309 (58%), Gaps = 21/309 (6%)

Query: 43  VVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
           V+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+QVG A+  K +
Sbjct: 1   VLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAIRSKIA 53

Query: 102 EG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF------- 153
           +G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P+++        
Sbjct: 54  DGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIP 113

Query: 154 --ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQ 208
             EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++  GL+ KP   Q
Sbjct: 114 KDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 173

Query: 209 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNK 268
           +E +    Q +L  FC+  DIV++AY+  GS           P  ++D  L ++A+K+ +
Sbjct: 174 VECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKR 233

Query: 269 TVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTK 328
           T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +   R L    
Sbjct: 234 TPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDI 293

Query: 329 WSKHPDYPF 337
           ++  P+YPF
Sbjct: 294 FAGPPNYPF 302


>S68290-1|AAD14012.1|  320|Homo sapiens chlordecone reductase
           homolog protein.
          Length = 320

 Score =  212 bits (518), Expect = 1e-54
 Identities = 122/318 (38%), Positives = 186/318 (58%), Gaps = 21/318 (6%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++ T         A+EAG+ HID+A+ Y  E+Q
Sbjct: 5   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 57

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW + H  E   PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 58  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPV 117

Query: 151 AMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  +   K   L KSIG+SNFN+  ++ I++  
Sbjct: 118 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKP 177

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GSL          P  ++D  
Sbjct: 178 GLQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSLREEPWVDPNSPVLLEDPV 237

Query: 259 LVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFD 318
           L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+Q+F+F LT EE   +   +
Sbjct: 238 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 297

Query: 319 TGYRTLPQTKWSKHPDYP 336
              R L    ++  P+YP
Sbjct: 298 RNVRYLTLDIFAGPPNYP 315


>J04794-1|AAA51711.1|  325|Homo sapiens ALDR1 protein.
          Length = 325

 Score =  204 bits (498), Expect = 3e-52
 Identities = 111/300 (37%), Positives = 171/300 (57%), Gaps = 22/300 (7%)

Query: 35  LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
           L +G  +P++ LGTW     K +  QV    + AV YAL  GY HID A  YG E ++G 
Sbjct: 8   LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58

Query: 95  ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
           AL +    G  + RE +F+T+KLWN+ H  E V PALRK+L +L LEY+DLYL+HWP A 
Sbjct: 59  ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 153 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
              D             D+  + +TW+ +      GL +++G+SNFN  QI  I+     
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178

Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
           +P+ LQ+E +  L Q EL   C+   + V AY+P GS   +   PD  P  +++  ++++
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237

Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           A+KY ++  Q+ LR+ ++   + +PKS+   RI QNI++FDF+ +PEE   L + +  +R
Sbjct: 238 AEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297


>CR457010-1|CAG33291.1|  325|Homo sapiens AKR1A1 protein.
          Length = 325

 Score =  204 bits (498), Expect = 3e-52
 Identities = 111/300 (37%), Positives = 171/300 (57%), Gaps = 22/300 (7%)

Query: 35  LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
           L +G  +P++ LGTW     K +  QV    + AV YAL  GY HID A  YG E ++G 
Sbjct: 8   LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58

Query: 95  ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
           AL +    G  + RE +F+T+KLWN+ H  E V PALRK+L +L LEY+DLYL+HWP A 
Sbjct: 59  ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 153 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
              D             D+  + +TW+ +      GL +++G+SNFN  QI  I+     
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178

Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
           +P+ LQ+E +  L Q EL   C+   + V AY+P GS   +   PD  P  +++  ++++
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237

Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           A+KY ++  Q+ LR+ ++   + +PKS+   RI QNI++FDF+ +PEE   L + +  +R
Sbjct: 238 AEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297


>BT007003-1|AAP35649.1|  325|Homo sapiens aldo-keto reductase family
           1, member A1 (aldehyde reductase) protein.
          Length = 325

 Score =  204 bits (498), Expect = 3e-52
 Identities = 111/300 (37%), Positives = 171/300 (57%), Gaps = 22/300 (7%)

Query: 35  LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
           L +G  +P++ LGTW     K +  QV    + AV YAL  GY HID A  YG E ++G 
Sbjct: 8   LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58

Query: 95  ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
           AL +    G  + RE +F+T+KLWN+ H  E V PALRK+L +L LEY+DLYL+HWP A 
Sbjct: 59  ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 153 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
              D             D+  + +TW+ +      GL +++G+SNFN  QI  I+     
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178

Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
           +P+ LQ+E +  L Q EL   C+   + V AY+P GS   +   PD  P  +++  ++++
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237

Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           A+KY ++  Q+ LR+ ++   + +PKS+   RI QNI++FDF+ +PEE   L + +  +R
Sbjct: 238 AEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297


>BC005394-1|AAH05394.1|  325|Homo sapiens aldo-keto reductase family
           1, member A1 (aldehyde reductase) protein.
          Length = 325

 Score =  204 bits (498), Expect = 3e-52
 Identities = 111/300 (37%), Positives = 171/300 (57%), Gaps = 22/300 (7%)

Query: 35  LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
           L +G  +P++ LGTW     K +  QV    + AV YAL  GY HID A  YG E ++G 
Sbjct: 8   LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58

Query: 95  ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
           AL +    G  + RE +F+T+KLWN+ H  E V PALRK+L +L LEY+DLYL+HWP A 
Sbjct: 59  ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 153 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
              D             D+  + +TW+ +      GL +++G+SNFN  QI  I+     
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178

Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
           +P+ LQ+E +  L Q EL   C+   + V AY+P GS   +   PD  P  +++  ++++
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237

Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           A+KY ++  Q+ LR+ ++   + +PKS+   RI QNI++FDF+ +PEE   L + +  +R
Sbjct: 238 AEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297


>BC000670-1|AAH00670.1|  325|Homo sapiens aldo-keto reductase family
           1, member A1 (aldehyde reductase) protein.
          Length = 325

 Score =  204 bits (498), Expect = 3e-52
 Identities = 111/300 (37%), Positives = 171/300 (57%), Gaps = 22/300 (7%)

Query: 35  LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
           L +G  +P++ LGTW     K +  QV    + AV YAL  GY HID A  YG E ++G 
Sbjct: 8   LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58

Query: 95  ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
           AL +    G  + RE +F+T+KLWN+ H  E V PALRK+L +L LEY+DLYL+HWP A 
Sbjct: 59  ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 153 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
              D             D+  + +TW+ +      GL +++G+SNFN  QI  I+     
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178

Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
           +P+ LQ+E +  L Q EL   C+   + V AY+P GS   +   PD  P  +++  ++++
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237

Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           A+KY ++  Q+ LR+ ++   + +PKS+   RI QNI++FDF+ +PEE   L + +  +R
Sbjct: 238 AEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297


>AL355480-3|CAI22459.1|  325|Homo sapiens aldo-keto reductase family
           1, member A1 (aldehydetase, 1 protein.
          Length = 325

 Score =  204 bits (498), Expect = 3e-52
 Identities = 111/300 (37%), Positives = 171/300 (57%), Gaps = 22/300 (7%)

Query: 35  LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
           L +G  +P++ LGTW     K +  QV    + AV YAL  GY HID A  YG E ++G 
Sbjct: 8   LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58

Query: 95  ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
           AL +    G  + RE +F+T+KLWN+ H  E V PALRK+L +L LEY+DLYL+HWP A 
Sbjct: 59  ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 153 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
              D             D+  + +TW+ +      GL +++G+SNFN  QI  I+     
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178

Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
           +P+ LQ+E +  L Q EL   C+   + V AY+P GS   +   PD  P  +++  ++++
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237

Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           A+KY ++  Q+ LR+ ++   + +PKS+   RI QNI++FDF+ +PEE   L + +  +R
Sbjct: 238 AEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297


>AF112485-1|AAF01260.1|  325|Homo sapiens aldehyde reductase
           protein.
          Length = 325

 Score =  204 bits (498), Expect = 3e-52
 Identities = 111/300 (37%), Positives = 171/300 (57%), Gaps = 22/300 (7%)

Query: 35  LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
           L +G  +P++ LGTW     K +  QV    + AV YAL  GY HID A  YG E ++G 
Sbjct: 8   LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58

Query: 95  ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
           AL +    G  + RE +F+T+KLWN+ H  E V PALRK+L +L LEY+DLYL+HWP A 
Sbjct: 59  ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 153 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
              D             D+  + +TW+ +      GL +++G+SNFN  QI  I+     
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178

Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
           +P+ LQ+E +  L Q EL   C+   + V AY+P GS   +   PD  P  +++  ++++
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237

Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           A+KY ++  Q+ LR+ ++   + +PKS+   RI QNI++FDF+ +PEE   L + +  +R
Sbjct: 238 AEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297


>AF036683-1|AAB92369.1|  325|Homo sapiens aldehyde reductase
           protein.
          Length = 325

 Score =  204 bits (498), Expect = 3e-52
 Identities = 111/300 (37%), Positives = 171/300 (57%), Gaps = 22/300 (7%)

Query: 35  LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
           L +G  +P++ LGTW     K +  QV    + AV YAL  GY HID A  YG E ++G 
Sbjct: 8   LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58

Query: 95  ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
           AL +    G  + RE +F+T+KLWN+ H  E V PALRK+L +L LEY+DLYL+HWP A 
Sbjct: 59  ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 153 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 202
              D             D+  + +TW+ +      GL +++G+SNFN  QI  I+     
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178

Query: 203 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSI 262
           +P+ LQ+E +  L Q EL   C+   + V AY+P GS   +   PD  P  +++  ++++
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237

Query: 263 AQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           A+KY ++  Q+ LR+ ++   + +PKS+   RI QNI++FDF+ +PEE   L + +  +R
Sbjct: 238 AEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297


>AL391427-2|CAI14727.1|  302|Homo sapiens aldo-keto reductase family
           1, member C-like 1 protein.
          Length = 302

 Score =  173 bits (421), Expect = 7e-43
 Identities = 114/321 (35%), Positives = 177/321 (55%), Gaps = 47/321 (14%)

Query: 32  TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
           +++L+ G  +PV+  GT+   H PK +  + T         A++ G+ HID+AY Y  E+
Sbjct: 10  SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62

Query: 91  QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
           +VG+A+ +K ++G +KRE IF T KLW ++   E V PAL +SL+ L  +YVDL++IH P
Sbjct: 63  EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122

Query: 150 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
            AM +            + +L+ V+  DTW   +   K GL                   
Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLR------------------ 164

Query: 199 SGLEKPSALQ-IELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPDAPPPRIDD 256
               KP+  Q +E +  L Q +L +FC+  DIV++AY+  GS   P    PD  P  +++
Sbjct: 165 ---YKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDC-PHLLEE 220

Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
             L SIA+K++++  QVALR+ ++ G VVL KS  +ERI++N Q+FDF LTPE+   +K+
Sbjct: 221 PILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPED---MKA 277

Query: 317 FDTGYRTLPQTKWSKHPDYPF 337
            D   R L     + HP +PF
Sbjct: 278 IDGLNRNLRYDNAANHPYFPF 298


>AL355303-1|CAI14201.1|  302|Homo sapiens aldo-keto reductase family
           1, member C-like 1 protein.
          Length = 302

 Score =  173 bits (421), Expect = 7e-43
 Identities = 114/321 (35%), Positives = 177/321 (55%), Gaps = 47/321 (14%)

Query: 32  TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
           +++L+ G  +PV+  GT+   H PK +  + T         A++ G+ HID+AY Y  E+
Sbjct: 10  SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62

Query: 91  QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
           +VG+A+ +K ++G +KRE IF T KLW ++   E V PAL +SL+ L  +YVDL++IH P
Sbjct: 63  EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122

Query: 150 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 198
            AM +            + +L+ V+  DTW   +   K GL                   
Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLR------------------ 164

Query: 199 SGLEKPSALQ-IELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPDAPPPRIDD 256
               KP+  Q +E +  L Q +L +FC+  DIV++AY+  GS   P    PD  P  +++
Sbjct: 165 ---YKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDC-PHLLEE 220

Query: 257 ERLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKS 316
             L SIA+K++++  QVALR+ ++ G VVL KS  +ERI++N Q+FDF LTPE+   +K+
Sbjct: 221 PILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPED---MKA 277

Query: 317 FDTGYRTLPQTKWSKHPDYPF 337
            D   R L     + HP +PF
Sbjct: 278 IDGLNRNLRYDNAANHPYFPF 298


>AB209796-1|BAD93033.1|  260|Homo sapiens aldo-keto reductase family
           1, member B1 variant protein.
          Length = 260

 Score =  173 bits (421), Expect = 7e-43
 Identities = 104/254 (40%), Positives = 152/254 (59%), Gaps = 23/254 (9%)

Query: 33  LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 92
           L L++G  +P++ LGTW    P G+V +       AV  A++ GY HID A+ Y  E++V
Sbjct: 2   LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 52

Query: 93  GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 151
           G A+ +K  E + KRE +FI +KLW +YHE+  V  A +K+L +L L+Y+DLYLIHWP  
Sbjct: 53  GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 112

Query: 152 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 200
                  F  D     +  + + LDTW  M +    GL K+IGISNFN  Q++ I++  G
Sbjct: 113 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 172

Query: 201 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERL 259
           L+ KP+  QIE +  L Q +L ++C+   IVV AY+P GS     A+P+  P  ++D R+
Sbjct: 173 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE-DPSLLEDPRI 231

Query: 260 VSIAQKYNKTVPQV 273
            +IA K+NKT  QV
Sbjct: 232 KAIAAKHNKTTAQV 245


>AB209017-1|BAD92254.1|  286|Homo sapiens aldo-keto reductase family
           1, member C2 variant protein.
          Length = 286

 Score =  164 bits (398), Expect = 5e-40
 Identities = 99/247 (40%), Positives = 145/247 (58%), Gaps = 21/247 (8%)

Query: 33  LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           ++L+ G  +PV+  GT+     PK K ++       AV  A+EAG+ HID+A+ Y  E+Q
Sbjct: 21  VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 73

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           VG A+  K ++G +KRE IF T+KLW++ H  E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 74  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 133

Query: 151 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 199
           ++          EN  +L D VD   TW  M   K  GL KSIG+SNFN   ++ I++  
Sbjct: 134 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 193

Query: 200 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDER 258
           GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D  
Sbjct: 194 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 253

Query: 259 LVSIAQK 265
           L ++A+K
Sbjct: 254 LCALAKK 260


>AL713867-3|CAI16410.1|  247|Homo sapiens aldo-keto reductase family
           1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
           protein.
          Length = 247

 Score =  162 bits (394), Expect = 1e-39
 Identities = 91/222 (40%), Positives = 136/222 (61%), Gaps = 13/222 (5%)

Query: 91  QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
           +VG A+  K ++G +KRE IF T+KLW + H  E V PAL +SL+NL L+YVDLYLIH+P
Sbjct: 26  EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85

Query: 150 IAM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 199
           +++          EN  +L D VD   TW  +   K  GL KSIG+SNFN+ Q++ I++ 
Sbjct: 86  VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145

Query: 200 -GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDE 257
            GL+ KP   Q+E +    Q +L  FC+  DIV++AY+  GS           P  ++D 
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDP 205

Query: 258 RLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNI 299
            L ++A+K+ +T   +ALR+ ++ G VVL KS +++RI QN+
Sbjct: 206 VLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNV 247


>AF263242-1|AAK58523.1|  320|Homo sapiens aldo-keto reductase
           loopADR protein.
          Length = 320

 Score =  120 bits (289), Expect = 7e-27
 Identities = 69/187 (36%), Positives = 101/187 (54%), Gaps = 9/187 (4%)

Query: 155 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 212
           N  +  + DFLDTW  M D    GL K+IG+SNFN EQ++R+++  GL  KP   QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198

Query: 213 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQ 272
             L Q  L  FC+  D+ V AY P G    S    D     ID+  +  IA+++ K+  Q
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLGG---SCEGVDL----IDNPVIKRIAKEHGKSPAQ 251

Query: 273 VALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKWSKH 332
           + +RF I+   +V+P S+    I++NIQ+FDF LT  + + + S +   R         H
Sbjct: 252 ILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNH 311

Query: 333 PDYPFQL 339
            DYPF +
Sbjct: 312 NDYPFHI 318



 Score = 94.7 bits (225), Expect = 4e-19
 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 10/113 (8%)

Query: 39  GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 98
           G+IP V L +W      GKV +       AV  A++AGY H D AY Y  E +VG  +  
Sbjct: 2   GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52

Query: 99  KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           K  EG ++RE +FI TKLW + H++  V  A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53  KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105


>BC002862-1|AAH02862.1|  307|Homo sapiens AKR1CL2 protein protein.
          Length = 307

 Score =  111 bits (268), Expect = 3e-24
 Identities = 64/170 (37%), Positives = 95/170 (55%), Gaps = 9/170 (5%)

Query: 155 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 212
           N  +  + DFLDTW  M D    GL K+IG+SNFN EQ++R+++  GL  KP   QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198

Query: 213 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQ 272
             L Q  L  FC+  D+ V AY P G    S    D     ID+  +  IA+++ K+  Q
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLGG---SCEGVDL----IDNPVIKRIAKEHGKSPAQ 251

Query: 273 VALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           + +RF I+   +V+P S+    I++NIQ+FDF LT  + + + S +   R
Sbjct: 252 ILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLR 301



 Score = 94.7 bits (225), Expect = 4e-19
 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 10/113 (8%)

Query: 39  GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 98
           G+IP V L +W      GKV +       AV  A++AGY H D AY Y  E +VG  +  
Sbjct: 2   GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52

Query: 99  KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           K  EG ++RE +FI TKLW + H++  V  A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53  KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105


>AB055603-1|BAC54568.1|  307|Homo sapiens aldo-keto reductase
           related protein 4 protein.
          Length = 307

 Score =  111 bits (268), Expect = 3e-24
 Identities = 64/170 (37%), Positives = 95/170 (55%), Gaps = 9/170 (5%)

Query: 155 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 212
           N  +  + DFLDTW  M D    GL K+IG+SNFN EQ++R+++  GL  KP   QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198

Query: 213 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQ 272
             L Q  L  FC+  D+ V AY P G    S    D     ID+  +  IA+++ K+  Q
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLGG---SCEGVDL----IDNPVIKRIAKEHGKSPAQ 251

Query: 273 VALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           + +RF I+   +V+P S+    I++NIQ+FDF LT  + + + S +   R
Sbjct: 252 ILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLR 301



 Score = 94.7 bits (225), Expect = 4e-19
 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 10/113 (8%)

Query: 39  GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 98
           G+IP V L +W      GKV +       AV  A++AGY H D AY Y  E +VG  +  
Sbjct: 2   GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52

Query: 99  KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           K  EG ++RE +FI TKLW + H++  V  A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53  KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105


>AL355480-2|CAI22458.1|  147|Homo sapiens aldo-keto reductase family
           1, member A1 (aldehydela) protein.
          Length = 147

 Score =  108 bits (260), Expect = 2e-23
 Identities = 58/124 (46%), Positives = 76/124 (61%), Gaps = 11/124 (8%)

Query: 35  LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 94
           L +G  +P++ LGTW     K +  QV    + AV YAL  GY HID A  YG E ++G 
Sbjct: 8   LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58

Query: 95  ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
           AL +    G  + RE +F+T+KLWN+ H  E V PALRK+L +L LEY+DLYL+HWP A 
Sbjct: 59  ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118

Query: 153 FEND 156
              D
Sbjct: 119 ERGD 122


>BC101205-1|AAI01206.1|  129|Homo sapiens aldo-keto reductase family
           1, member C-like 1 protein.
          Length = 129

 Score = 97.5 bits (232), Expect = 6e-20
 Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 9/123 (7%)

Query: 32  TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
           +++L+ G  +PV+  GT+   H PK +  + T         A++ G+ HID+AY Y  E+
Sbjct: 10  SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62

Query: 91  QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
           +VG+A+ +K ++G +KRE IF T KLW ++   E V PAL +SL+ L  +YVDL++IH P
Sbjct: 63  EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122

Query: 150 IAM 152
            AM
Sbjct: 123 FAM 125


>BC101204-1|AAI01205.1|  129|Homo sapiens aldo-keto reductase family
           1, member C-like 1 protein.
          Length = 129

 Score = 97.5 bits (232), Expect = 6e-20
 Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 9/123 (7%)

Query: 32  TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
           +++L+ G  +PV+  GT+   H PK +  + T         A++ G+ HID+AY Y  E+
Sbjct: 10  SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62

Query: 91  QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
           +VG+A+ +K ++G +KRE IF T KLW ++   E V PAL +SL+ L  +YVDL++IH P
Sbjct: 63  EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122

Query: 150 IAM 152
            AM
Sbjct: 123 FAM 125


>AK131335-1|BAD18494.1|  129|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16347 fis, clone TESTI2036288, moderately
           similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
          Length = 129

 Score = 97.5 bits (232), Expect = 6e-20
 Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 9/123 (7%)

Query: 32  TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 90
           +++L+ G  +PV+  GT+   H PK +  + T         A++ G+ HID+AY Y  E+
Sbjct: 10  SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62

Query: 91  QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 149
           +VG+A+ +K ++G +KRE IF T KLW ++   E V PAL +SL+ L  +YVDL++IH P
Sbjct: 63  EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122

Query: 150 IAM 152
            AM
Sbjct: 123 FAM 125


>AB040822-1|BAC54567.1|  222|Homo sapiens aldo-keto reductase
           related protein 3 protein.
          Length = 222

 Score = 94.7 bits (225), Expect = 4e-19
 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 10/113 (8%)

Query: 39  GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 98
           G+IP V L +W      GKV +       AV  A++AGY H D AY Y  E +VG  +  
Sbjct: 2   GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52

Query: 99  KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           K  EG ++RE +FI TKLW + H++  V  A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53  KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105



 Score = 50.8 bits (116), Expect = 7e-06
 Identities = 22/68 (32%), Positives = 37/68 (54%)

Query: 272 QVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTLPQTKWSK 331
           ++ +RF I+   +V+P S+    I++NIQ+FDF LT  + + + S +   R         
Sbjct: 153 EILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKN 212

Query: 332 HPDYPFQL 339
           H DYPF +
Sbjct: 213 HKDYPFHI 220


>AB040821-1|BAC54566.1|  263|Homo sapiens aldo-keto reductase
           related protein 2 protein.
          Length = 263

 Score = 94.7 bits (225), Expect = 4e-19
 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 10/113 (8%)

Query: 39  GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 98
           G+IP V L +W      GKV +       AV  A++AGY H D AY Y  E +VG  +  
Sbjct: 2   GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52

Query: 99  KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           K  EG ++RE +FI TKLW + H++  V  A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53  KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)

Query: 155 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 212
           N  +  + DFLDTW  M D    GL K+IG+SNFN EQ++R+++  GL  KP   QI + 
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198

Query: 213 LNLQQ 217
             +Q+
Sbjct: 199 FQIQR 203



 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 23/75 (30%), Positives = 39/75 (52%)

Query: 265 KYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYRTL 324
           ++     Q+ +RF I+   +V+P S+    I++NIQ+FDF LT  + + + S +   R  
Sbjct: 187 RFKPLTNQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLA 246

Query: 325 PQTKWSKHPDYPFQL 339
                  H DYPF +
Sbjct: 247 MFPITKNHKDYPFHI 261


>AB040820-1|BAC54565.1|  250|Homo sapiens aldo-keto reductase
           related protein 1 protein.
          Length = 250

 Score = 94.7 bits (225), Expect = 4e-19
 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 10/113 (8%)

Query: 39  GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 98
           G+IP V L +W      GKV +       AV  A++AGY H D AY Y  E +VG  +  
Sbjct: 2   GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52

Query: 99  KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           K  EG ++RE +FI TKLW + H++  V  A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53  KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)

Query: 155 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 212
           N  +  + DFLDTW  M D    GL K+IG+SNFN EQ++R+++  GL  KP   QI + 
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198

Query: 213 LNLQQ 217
             +Q+
Sbjct: 199 FQIQR 203



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 18/58 (31%), Positives = 33/58 (56%)

Query: 265 KYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSFDTGYR 322
           ++     Q+ +RF I+   +V+P S+    I++NIQ+FDF LT  + + + S +   R
Sbjct: 187 RFKPLTNQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLR 244


>AB037902-1|BAA92887.1|  130|Homo sapiens truncated aldo-keto
           reductase protein.
          Length = 130

 Score = 90.2 bits (214), Expect = 9e-18
 Identities = 46/122 (37%), Positives = 77/122 (63%), Gaps = 7/122 (5%)

Query: 32  TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 91
           +++L+ G  +P++  GT +  +     V ++N  E+AV  A++ GY HID+AY +  E+ 
Sbjct: 8   SVKLNDGKFMPILGFGTSVARK-----VAMSN-VEEAVQVAIDVGYRHIDSAYTHLNEEG 61

Query: 92  VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 150
           +G+A+ KK + G +KR+ IF TTK+W ++   E V   L  SL+ L L Y+DLYL H+P+
Sbjct: 62  IGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121

Query: 151 AM 152
            +
Sbjct: 122 PL 123


>AK058142-1|BAB71682.1|  146|Homo sapiens protein ( Homo sapiens
           cDNA FLJ25413 fis, clone TST03402, highly similar to
           3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
          Length = 146

 Score = 73.7 bits (173), Expect = 8e-13
 Identities = 34/75 (45%), Positives = 52/75 (69%), Gaps = 2/75 (2%)

Query: 167 TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFC 224
           TW  M   K  GL KS+G+SNFN+ Q++ I++  GL+ KP + Q+E +    QP+L KFC
Sbjct: 28  TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87

Query: 225 RENDIVVMAYTPFGS 239
           +++DIV+ AY+P G+
Sbjct: 88  QQHDIVITAYSPLGT 102


>AF044961-1|AAC15671.1|   85|Homo sapiens aldose reductase-related
           protein protein.
          Length = 85

 Score = 68.5 bits (160), Expect = 3e-11
 Identities = 34/80 (42%), Positives = 48/80 (60%)

Query: 258 RLVSIAQKYNKTVPQVALRFLIELGAVVLPKSVHKERIEQNIQLFDFSLTPEEFNLLKSF 317
           ++  IA K+ KT  QV +RF I+   +V+PKSV   RI +NIQ+FDF L+ EE   + SF
Sbjct: 2   KIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSF 61

Query: 318 DTGYRTLPQTKWSKHPDYPF 337
           +  +R     + S   DYPF
Sbjct: 62  NRNWRACNVLQSSHLEDYPF 81


>U33429-1|AAC50955.1|  367|Homo sapiens K+ channel beta 2 subunit
           protein.
          Length = 367

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 45  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156

Query: 146 IHWP 149
            + P
Sbjct: 157 ANRP 160


>CR542287-1|CAG47082.1|  353|Homo sapiens KCNAB2 protein.
          Length = 353

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 31  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 86  GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142

Query: 146 IHWP 149
            + P
Sbjct: 143 ANRP 146


>BC130413-1|AAI30414.1|  367|Homo sapiens potassium voltage-gated
           channel, shaker-related subfamily, beta member 2
           protein.
          Length = 367

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 45  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156

Query: 146 IHWP 149
            + P
Sbjct: 157 ANRP 160


>BC126424-1|AAI26425.1|  367|Homo sapiens potassium voltage-gated
           channel, shaker-related subfamily, beta member 2
           protein.
          Length = 367

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 45  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156

Query: 146 IHWP 149
            + P
Sbjct: 157 ANRP 160


>BC110351-1|AAI10352.1|  395|Homo sapiens KCNAB2 protein protein.
          Length = 395

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 45  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156

Query: 146 IHWP 149
            + P
Sbjct: 157 ANRP 160


>AL035406-6|CAI19886.1|  253|Homo sapiens potassium voltage-gated
           channel, shaker-related subfamily, beta member 2
           protein.
          Length = 253

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 45  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156

Query: 146 IHWP 149
            + P
Sbjct: 157 ANRP 160


>AL035406-5|CAI19887.1|  254|Homo sapiens potassium voltage-gated
           channel, shaker-related subfamily, beta member 2
           protein.
          Length = 254

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 31  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 86  GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142

Query: 146 IHWP 149
            + P
Sbjct: 143 ANRP 146


>AL035406-4|CAC08512.1|  367|Homo sapiens potassium voltage-gated
           channel, shaker-related subfamily, beta member 2
           protein.
          Length = 367

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 45  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156

Query: 146 IHWP 149
            + P
Sbjct: 157 ANRP 160


>AL035406-3|CAI19885.1|  353|Homo sapiens potassium voltage-gated
           channel, shaker-related subfamily, beta member 2
           protein.
          Length = 353

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 31  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 86  GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142

Query: 146 IHWP 149
            + P
Sbjct: 143 ANRP 146


>AK131252-1|BAD18431.1|  415|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16180 fis, clone BRHIP3000240, highly  similar
           to Homo sapiens potassium channel beta 2 subunit
           (HKvbeta2.2) mRNA. ).
          Length = 415

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 78  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 132

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 133 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 189

Query: 146 IHWP 149
            + P
Sbjct: 190 ANRP 193


>AF044253-1|AAB99859.1|  353|Homo sapiens potassium channel beta 2
           subunit protein.
          Length = 353

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 31  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 86  GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142

Query: 146 IHWP 149
            + P
Sbjct: 143 ANRP 146


>AF029749-1|AAB84170.1|  367|Homo sapiens potassium channel beta 2
           subunit protein.
          Length = 367

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 45  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE L LEYVD+  
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156

Query: 146 IHWP 149
            + P
Sbjct: 157 ANRP 160


>X83127-1|CAA58208.1|  401|Homo sapiens voltage gated potassium
           channels, beta subunit protein.
          Length = 401

 Score = 48.0 bits (109), Expect = 5e-05
 Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 17/123 (13%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTA--YKYGIEDQVG 93
           SG  +  + LGTW+         Q++++  E+ +  A E+G    DTA  Y  G  + + 
Sbjct: 79  SGLRVSCLGLGTWVTFGG-----QISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVIL 133

Query: 94  RALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLI 146
            ++ KK  +G +R S+ ITTKL W    E      R+ +I  L+ SL+ L LEYVD+   
Sbjct: 134 GSIIKK--KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFA 191

Query: 147 HWP 149
           + P
Sbjct: 192 NRP 194


>U33428-1|AAC50953.1|  401|Homo sapiens K+ channel beta 1a subunit
           protein.
          Length = 401

 Score = 48.0 bits (109), Expect = 5e-05
 Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 17/123 (13%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTA--YKYGIEDQVG 93
           SG  +  + LGTW+         Q++++  E+ +  A E+G    DTA  Y  G  + + 
Sbjct: 79  SGLRVSCLGLGTWVTFGG-----QISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVIL 133

Query: 94  RALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLI 146
            ++ KK  +G +R S+ ITTKL W    E      R+ +I  L+ SL+ L LEYVD+   
Sbjct: 134 GSIIKK--KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFA 191

Query: 147 HWP 149
           + P
Sbjct: 192 NRP 194


>U16953-1|AAC50122.1|  408|Homo sapiens potassium channel beta3
           subunit protein.
          Length = 408

 Score = 48.0 bits (109), Expect = 5e-05
 Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 17/123 (13%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTA--YKYGIEDQVG 93
           SG  +  + LGTW+         Q++++  E+ +  A E+G    DTA  Y  G  + + 
Sbjct: 86  SGLRVSCLGLGTWVTFGG-----QISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVIL 140

Query: 94  RALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLI 146
            ++ KK  +G +R S+ ITTKL W    E      R+ +I  L+ SL+ L LEYVD+   
Sbjct: 141 GSIIKK--KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFA 198

Query: 147 HWP 149
           + P
Sbjct: 199 NRP 201


>L47665-1|AAC41926.1|  419|Homo sapiens K+ channel beta-subunit
           protein.
          Length = 419

 Score = 48.0 bits (109), Expect = 5e-05
 Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 17/123 (13%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTA--YKYGIEDQVG 93
           SG  +  + LGTW+         Q++++  E+ +  A E+G    DTA  Y  G  + + 
Sbjct: 97  SGLRVSCLGLGTWVTFGG-----QISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVIL 151

Query: 94  RALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLI 146
            ++ KK  +G +R S+ ITTKL W    E      R+ +I  L+ SL+ L LEYVD+   
Sbjct: 152 GSIIKK--KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFA 209

Query: 147 HWP 149
           + P
Sbjct: 210 NRP 212


>L39833-1|AAC37573.1|  408|Homo sapiens K+ channel beta-subunit
           protein.
          Length = 408

 Score = 48.0 bits (109), Expect = 5e-05
 Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 17/123 (13%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTA--YKYGIEDQVG 93
           SG  +  + LGTW+         Q++++  E+ +  A E+G    DTA  Y  G  + + 
Sbjct: 86  SGLRVSCLGLGTWVTFGG-----QISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVIL 140

Query: 94  RALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLI 146
            ++ KK  +G +R S+ ITTKL W    E      R+ +I  L+ SL+ L LEYVD+   
Sbjct: 141 GSIIKK--KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFA 198

Query: 147 HWP 149
           + P
Sbjct: 199 NRP 201


>BC043166-1|AAH43166.1|  401|Homo sapiens potassium voltage-gated
           channel, shaker-related subfamily, beta member 1
           protein.
          Length = 401

 Score = 48.0 bits (109), Expect = 5e-05
 Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 17/123 (13%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTA--YKYGIEDQVG 93
           SG  +  + LGTW+         Q++++  E+ +  A E+G    DTA  Y  G  + + 
Sbjct: 79  SGLRVSCLGLGTWVTFGG-----QISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVIL 133

Query: 94  RALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLI 146
            ++ KK  +G +R S+ ITTKL W    E      R+ +I  L+ SL+ L LEYVD+   
Sbjct: 134 GSIIKK--KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFA 191

Query: 147 HWP 149
           + P
Sbjct: 192 NRP 194


>CR542264-1|CAG47060.1|  353|Homo sapiens KCNAB2 protein.
          Length = 353

 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 19/124 (15%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q+T++  EQ +  A + G    DTA  Y     E  +
Sbjct: 31  SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 145
           G  + KK   G +R S+ ITTK+ W    E      R+ +I  L+ SLE   LEYVD+  
Sbjct: 86  GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERRQLEYVDVVF 142

Query: 146 IHWP 149
            + P
Sbjct: 143 ANRP 146


>AB028065-1|BAA88489.1|   67|Homo sapiens prostaglandin F synthase
           protein.
          Length = 67

 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 2/49 (4%)

Query: 158 LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 204
           + D VD   TW  M   K  GL KSIG+SNFN+ Q++ I++  GL+ KP
Sbjct: 15  IFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 63


>BC099634-1|AAH99634.1|  404|Homo sapiens potassium voltage-gated
           channel, shaker-related subfamily, beta member 3
           protein.
          Length = 404

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 19/118 (16%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q++++T + V+  A E G    DTA  Y     E  +
Sbjct: 86  SGLRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTL 140

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 143
           G  L  K   G +R S  ITTK+ W    E      R+ +I  LR SLE L L YVD+
Sbjct: 141 GNILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195


>BC096234-1|AAH96234.1|  404|Homo sapiens potassium voltage-gated
           channel, shaker-related subfamily, beta member 3
           protein.
          Length = 404

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 19/118 (16%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q++++T + V+  A E G    DTA  Y     E  +
Sbjct: 86  SGLRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTL 140

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 143
           G  L  K   G +R S  ITTK+ W    E      R+ +I  LR SLE L L YVD+
Sbjct: 141 GNILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195


>BC096232-1|AAH96232.1|  404|Homo sapiens potassium voltage-gated
           channel, shaker-related subfamily, beta member 3
           protein.
          Length = 404

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 19/118 (16%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQV 92
           SG  +  + LGTW+         Q++++T + V+  A E G    DTA  Y     E  +
Sbjct: 86  SGLRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTL 140

Query: 93  GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 143
           G  L  K   G +R S  ITTK+ W    E      R+ +I  LR SLE L L YVD+
Sbjct: 141 GNILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195


>AF016411-1|AAB92499.1|  404|Homo sapiens KCNA3.1B protein.
          Length = 404

 Score = 44.4 bits (100), Expect = 6e-04
 Identities = 40/117 (34%), Positives = 55/117 (47%), Gaps = 19/117 (16%)

Query: 38  GGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQVG 93
           G  +  + LGTW+         Q++++T + V+  A E G    DTA  Y     E  +G
Sbjct: 87  GVRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLG 141

Query: 94  RALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 143
             L  K   G +R S  ITTK+ W    E      R+ +I  LR SLE L L YVD+
Sbjct: 142 NILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195


>AB037905-2|BAA92890.1|   45|Homo sapiens truncated aldo-keto
           reductase protein.
          Length = 45

 Score = 37.9 bits (84), Expect = 0.051
 Identities = 15/38 (39%), Positives = 23/38 (60%)

Query: 115 LWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 152
           +W ++   E V   L  SL+ L L Y+DLYL H+P+ +
Sbjct: 1   VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 38


>AF026947-1|AAC52104.1|  330|Homo sapiens aflatoxin aldehyde
           reductase AFAR protein.
          Length = 330

 Score = 35.5 bits (78), Expect = 0.27
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 68  AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 124
           AV   LE G+T +DTA+ Y  G  + +   L      G  R  I      W+    + + 
Sbjct: 30  AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89

Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
           V   L  SL+ L    VDL+ +H P    ++ T ++     +T        + G    +G
Sbjct: 90  VRSQLETSLKRLQCPQVDLFYLHTP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140

Query: 185 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 237
           +SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   AY P  
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200

Query: 238 GSLFPSK 244
           G L   K
Sbjct: 201 GGLLTGK 207


>Y16675-1|CAA76347.1|  330|Homo sapiens aflatoxin B1-aldehyde
           reductase protein.
          Length = 330

 Score = 35.1 bits (77), Expect = 0.36
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 68  AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 124
           AV   LE G+T +DTA+ Y  G  + +   L      G  R  I      W+    + + 
Sbjct: 30  AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89

Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
           V   L  SL+ L    VDL+ +H P    ++ T ++     +T        + G    +G
Sbjct: 90  VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140

Query: 185 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 237
           +SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   AY P  
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200

Query: 238 GSLFPSK 244
           G L   K
Sbjct: 201 GGLLTGK 207


>BT007347-1|AAP36011.1|  330|Homo sapiens aldo-keto reductase family
           7, member A2 (aflatoxin aldehyde reductase) protein.
          Length = 330

 Score = 35.1 bits (77), Expect = 0.36
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 68  AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 124
           AV   LE G+T +DTA+ Y  G  + +   L      G  R  I      W+    + + 
Sbjct: 30  AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89

Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
           V   L  SL+ L    VDL+ +H P    ++ T ++     +T        + G    +G
Sbjct: 90  VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140

Query: 185 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 237
           +SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   AY P  
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200

Query: 238 GSLFPSK 244
           G L   K
Sbjct: 201 GGLLTGK 207


>BC013996-1|AAH13996.1|  330|Homo sapiens AKR7A2 protein protein.
          Length = 330

 Score = 35.1 bits (77), Expect = 0.36
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 68  AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 124
           AV   LE G+T +DTA+ Y  G  + +   L      G  R  I      W+    + + 
Sbjct: 30  AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89

Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
           V   L  SL+ L    VDL+ +H P    ++ T ++     +T        + G    +G
Sbjct: 90  VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140

Query: 185 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 237
           +SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   AY P  
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200

Query: 238 GSLFPSK 244
           G L   K
Sbjct: 201 GGLLTGK 207


>BC012171-1|AAH12171.1|  330|Homo sapiens AKR7A2 protein protein.
          Length = 330

 Score = 35.1 bits (77), Expect = 0.36
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 68  AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 124
           AV   LE G+T +DTA+ Y  G  + +   L      G  R  I      W+    + + 
Sbjct: 30  AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89

Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
           V   L  SL+ L    VDL+ +H P    ++ T ++     +T        + G    +G
Sbjct: 90  VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140

Query: 185 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 237
           +SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   AY P  
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200

Query: 238 GSLFPSK 244
           G L   K
Sbjct: 201 GGLLTGK 207


>BC011586-1|AAH11586.1|  330|Homo sapiens AKR7A2 protein protein.
          Length = 330

 Score = 35.1 bits (77), Expect = 0.36
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 68  AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 124
           AV   LE G+T +DTA+ Y  G  + +   L      G  R  I      W+    + + 
Sbjct: 30  AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89

Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
           V   L  SL+ L    VDL+ +H P    ++ T ++     +T        + G    +G
Sbjct: 90  VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140

Query: 185 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 237
           +SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   AY P  
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200

Query: 238 GSLFPSK 244
           G L   K
Sbjct: 201 GGLLTGK 207


>BC010852-1|AAH10852.1|  330|Homo sapiens AKR7A2 protein protein.
          Length = 330

 Score = 35.1 bits (77), Expect = 0.36
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 68  AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 124
           AV   LE G+T +DTA+ Y  G  + +   L      G  R  I      W+    + + 
Sbjct: 30  AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89

Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
           V   L  SL+ L    VDL+ +H P    ++ T ++     +T        + G    +G
Sbjct: 90  VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140

Query: 185 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 237
           +SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   AY P  
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200

Query: 238 GSLFPSK 244
           G L   K
Sbjct: 201 GGLLTGK 207


>BC007352-1|AAH07352.2|  358|Homo sapiens AKR7A2 protein protein.
          Length = 358

 Score = 35.1 bits (77), Expect = 0.36
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 68  AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 124
           AV   LE G+T +DTA+ Y  G  + +   L      G  R  I      W+    + + 
Sbjct: 58  AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 117

Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
           V   L  SL+ L    VDL+ +H P    ++ T ++     +T        + G    +G
Sbjct: 118 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 168

Query: 185 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 237
           +SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   AY P  
Sbjct: 169 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 228

Query: 238 GSLFPSK 244
           G L   K
Sbjct: 229 GGLLTGK 235


>BC004111-1|AAH04111.3|  330|Homo sapiens AKR7A2 protein protein.
          Length = 330

 Score = 35.1 bits (77), Expect = 0.36
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 68  AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 124
           AV   LE G+T +DTA+ Y  G  + +   L      G  R  I      W+    + + 
Sbjct: 30  AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89

Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
           V   L  SL+ L    VDL+ +H P    ++ T ++     +T        + G    +G
Sbjct: 90  VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140

Query: 185 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 237
           +SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   AY P  
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200

Query: 238 GSLFPSK 244
           G L   K
Sbjct: 201 GGLLTGK 207


>AL035413-8|CAB72321.1|  330|Homo sapiens aldo-keto reductase family
           7, member A2 (aflatoxin aldehyde reductase) protein.
          Length = 330

 Score = 35.1 bits (77), Expect = 0.36
 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 68  AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 124
           AV   LE G+T +DTA+ Y  G  + +   L      G  R  I      W+    + + 
Sbjct: 30  AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89

Query: 125 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 184
           V   L  SL+ L    VDL+ +H P    ++ T ++     +T        + G    +G
Sbjct: 90  VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140

Query: 185 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 237
           +SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   AY P  
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200

Query: 238 GSLFPSK 244
           G L   K
Sbjct: 201 GGLLTGK 207


>D83174-1|BAA11829.1|  418|Homo sapiens collagen binding protein 2
           protein.
          Length = 418

 Score = 34.7 bits (76), Expect = 0.48
 Identities = 31/163 (19%), Positives = 69/163 (42%), Gaps = 8/163 (4%)

Query: 42  PVVALGTWLGHRPKGKVVQVTNDTEQ---AVIYALEAGYTHIDTAYKYGIEDQVGRALTK 98
           P+ ++  W      GK+ +VT D E+   A++        H D  + + + D  G  +T+
Sbjct: 169 PLQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTR 228

Query: 99  KFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL 158
            ++ G+    +   T L+N Y + ++ +  +   L +  L  + + + H    +   + L
Sbjct: 229 SYTVGV---MMMHRTGLYNYYDDEKEKLQIVEMPLAH-KLSSLIILMPHHVEPLERLEKL 284

Query: 159 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
           L   + L  W G +  K + ++   G+     +  + +   GL
Sbjct: 285 LTK-EQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGL 326


>AY780786-1|AAV98356.1|  372|Homo sapiens potassium voltage-gated
           channel beta subunit protein.
          Length = 372

 Score = 34.3 bits (75), Expect = 0.63
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 11/92 (11%)

Query: 37  SGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTA--YKYGIEDQVG 93
           SG  +  + LGTW+         Q++++  E+ +  A E+G    DTA  Y  G  + + 
Sbjct: 79  SGLRVSCLGLGTWVTFGG-----QISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVIL 133

Query: 94  RALTKKFSEGLKRESIFITTKL-WNSYHEREQ 124
            ++ KK  +G +R S+ ITTKL W    E E+
Sbjct: 134 GSIIKK--KGWRRSSLVITTKLYWGGKAETER 163


>BC075018-1|AAH75018.1|  599|Homo sapiens DEAQ box polypeptide 1
           (RNA-dependent ATPase) protein.
          Length = 599

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 8/99 (8%)

Query: 172 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 231
           +DA+K+ +T  +   +F+   IQ +IDSGLE  S     +    Q       C+     +
Sbjct: 197 MDARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRL 256

Query: 232 MAY-TPFGS---LFP-SKAQPDAPP---PRIDDERLVSI 262
            A   P GS   L+P S  + +APP   PR+ +E L S+
Sbjct: 257 RARGFPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSL 295


>BC070087-1|AAH70087.1|  418|Homo sapiens serpin peptidase
           inhibitor, clade H (heat shock protein 47), member 1,
           (collage protein.
          Length = 418

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 30/160 (18%), Positives = 68/160 (42%), Gaps = 8/160 (5%)

Query: 45  ALGTWLGHRPKGKVVQVTNDTEQ---AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
           ++  W      GK+ +VT D E+   A++        H D  + + + D  G  +T+ ++
Sbjct: 172 SINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYT 231

Query: 102 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDN 161
            G+    +   T L+N Y + ++ +  +   L +  L  + +++ H    +   + LL  
Sbjct: 232 VGV---MMMHRTGLYNYYDDEKEKLQIVEMPLAH-KLSSLIIFMPHHVEPLERLEKLLTK 287

Query: 162 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
            + L  W G +  K + ++   G+     +  + +   GL
Sbjct: 288 -EQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGL 326


>AK074337-1|BAB85056.1|  599|Homo sapiens protein ( Homo sapiens
           cDNA FLJ23757 fis, clone HEP17946, highly similar to Mus
           musculus DEAQ RNA-dependent ATPase DQX1 mRNA. ).
          Length = 599

 Score = 33.9 bits (74), Expect = 0.83
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 8/99 (8%)

Query: 172 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 231
           +DA+K+ +T  +   +F+   IQ +IDSGLE  S     +    Q       C+     +
Sbjct: 197 MDARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRL 256

Query: 232 MAY-TPFGS---LFP-SKAQPDAPP---PRIDDERLVSI 262
            A   P GS   L+P S  + +APP   PR+ +E L S+
Sbjct: 257 RARGFPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSL 295


>X61598-1|CAA43795.1|  417|Homo sapiens colligin protein.
          Length = 417

 Score = 33.1 bits (72), Expect = 1.5
 Identities = 30/160 (18%), Positives = 68/160 (42%), Gaps = 8/160 (5%)

Query: 45  ALGTWLGHRPKGKVVQVTNDTEQ---AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
           ++  W      GK+ +VT D E+   A++        H D  + + + D  G  +T+ ++
Sbjct: 171 SINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYT 230

Query: 102 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDN 161
            G+   ++   T L+N Y + ++ +  +   L +  L  + + + H    +   + LL  
Sbjct: 231 VGV---TMMHRTGLYNYYDDEKEKLQLVEMPLAH-KLSSLIILMPHHVEPLERLEKLLTK 286

Query: 162 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
            + L  W G +  K + ++   G+     +  + +   GL
Sbjct: 287 -EQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGL 325


>BT007094-1|AAP35758.1|  418|Homo sapiens serine (or cysteine)
           proteinase inhibitor, clade H (heat shock protein 47),
           mem protein.
          Length = 418

 Score = 32.3 bits (70), Expect = 2.5
 Identities = 30/160 (18%), Positives = 67/160 (41%), Gaps = 8/160 (5%)

Query: 45  ALGTWLGHRPKGKVVQVTNDTEQ---AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
           ++  W      GK+ +VT D E+   A++        H D  + + + D  G  +T+ ++
Sbjct: 172 SINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYT 231

Query: 102 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDN 161
            G+    +   T L+N Y + ++ +  +   L +  L  + + + H    +   + LL  
Sbjct: 232 VGV---MMMHRTGLYNYYDDEKEKLQIVEMPLAH-KLSSLIILMPHHVEPLERLEKLLTK 287

Query: 162 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
            + L  W G +  K + ++   G+     +  + +   GL
Sbjct: 288 -EQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGL 326


>BC036298-1|AAH36298.2|  418|Homo sapiens serpin peptidase
           inhibitor, clade H (heat shock protein 47), member 1,
           (collage protein.
          Length = 418

 Score = 32.3 bits (70), Expect = 2.5
 Identities = 30/160 (18%), Positives = 67/160 (41%), Gaps = 8/160 (5%)

Query: 45  ALGTWLGHRPKGKVVQVTNDTEQ---AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
           ++  W      GK+ +VT D E+   A++        H D  + + + D  G  +T+ ++
Sbjct: 172 SINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYT 231

Query: 102 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDN 161
            G+    +   T L+N Y + ++ +  +   L +  L  + + + H    +   + LL  
Sbjct: 232 VGV---MMMHRTGLYNYYDDEKEKLQIVEMPLAH-KLSSLIILMPHHVEPLERLEKLLTK 287

Query: 162 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
            + L  W G +  K + ++   G+     +  + +   GL
Sbjct: 288 -EQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGL 326


>BC014623-1|AAH14623.1|  418|Homo sapiens serpin peptidase
           inhibitor, clade H (heat shock protein 47), member 1,
           (collage protein.
          Length = 418

 Score = 32.3 bits (70), Expect = 2.5
 Identities = 30/160 (18%), Positives = 67/160 (41%), Gaps = 8/160 (5%)

Query: 45  ALGTWLGHRPKGKVVQVTNDTEQ---AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
           ++  W      GK+ +VT D E+   A++        H D  + + + D  G  +T+ ++
Sbjct: 172 SINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYT 231

Query: 102 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDN 161
            G+    +   T L+N Y + ++ +  +   L +  L  + + + H    +   + LL  
Sbjct: 232 VGV---MMMHRTGLYNYYDDEKEKLQIVEMPLAH-KLSSLIILMPHHVEPLERLEKLLTK 287

Query: 162 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
            + L  W G +  K + ++   G+     +  + +   GL
Sbjct: 288 -EQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGL 326


>AY744367-1|AAU95378.1|  418|Homo sapiens arsenic-transactivated
           protein 3 protein.
          Length = 418

 Score = 32.3 bits (70), Expect = 2.5
 Identities = 30/160 (18%), Positives = 67/160 (41%), Gaps = 8/160 (5%)

Query: 45  ALGTWLGHRPKGKVVQVTNDTEQ---AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
           ++  W      GK+ +VT D E+   A++        H D  + + + D  G  +T+ ++
Sbjct: 172 SINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYT 231

Query: 102 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDN 161
            G+    +   T L+N Y + ++ +  +   L +  L  + + + H    +   + LL  
Sbjct: 232 VGV---MMMHRTGLYNYYDDEKEKLQIVEMPLAH-KLSSLIILMPHHVEPLERLEKLLTK 287

Query: 162 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
            + L  W G +  K + ++   G+     +  + +   GL
Sbjct: 288 -EQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGL 326


>AY264853-1|AAP93914.1|  418|Homo sapiens proliferation-inducing
           gene 14 protein.
          Length = 418

 Score = 32.3 bits (70), Expect = 2.5
 Identities = 30/160 (18%), Positives = 67/160 (41%), Gaps = 8/160 (5%)

Query: 45  ALGTWLGHRPKGKVVQVTNDTEQ---AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
           ++  W      GK+ +VT D E+   A++        H D  + + + D  G  +T+ ++
Sbjct: 172 SINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYT 231

Query: 102 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDN 161
            G+    +   T L+N Y + ++ +  +   L +  L  + + + H    +   + LL  
Sbjct: 232 VGV---MMMHRTGLYNYYDDEKEKLQIVEMPLAH-KLSSLIILMPHHVEPLERLEKLLTK 287

Query: 162 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
            + L  W G +  K + ++   G+     +  + +   GL
Sbjct: 288 -EQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGL 326


>AB044779-1|BAA96789.1|  418|Homo sapiens rheumatoid arthritis
           related antigen RA-A47 protein.
          Length = 418

 Score = 32.3 bits (70), Expect = 2.5
 Identities = 30/160 (18%), Positives = 67/160 (41%), Gaps = 8/160 (5%)

Query: 45  ALGTWLGHRPKGKVVQVTNDTEQ---AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
           ++  W      GK+ +VT D E+   A++        H D  + + + D  G  +T+ ++
Sbjct: 172 SINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYT 231

Query: 102 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDN 161
            G+    +   T L+N Y + ++ +  +   L +  L  + + + H    +   + LL  
Sbjct: 232 VGV---MMMHRTGLYNYYDDEKEKLQIVEMPLAH-KLSSLIILMPHHVEPLERLEKLLTK 287

Query: 162 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
            + L  W G +  K + ++   G+     +  + +   GL
Sbjct: 288 -EQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGL 326


>AB044778-1|BAA96788.1|  418|Homo sapiens rheumatoid arthritis
           related antigen RA-A47 protein.
          Length = 418

 Score = 32.3 bits (70), Expect = 2.5
 Identities = 30/160 (18%), Positives = 67/160 (41%), Gaps = 8/160 (5%)

Query: 45  ALGTWLGHRPKGKVVQVTNDTEQ---AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 101
           ++  W      GK+ +VT D E+   A++        H D  + + + D  G  +T+ ++
Sbjct: 172 SINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYT 231

Query: 102 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDN 161
            G+    +   T L+N Y + ++ +  +   L +  L  + + + H    +   + LL  
Sbjct: 232 VGV---MMMHRTGLYNYYDDEKEKLQIVEMPLAH-KLSSLIILMPHHVEPLERLEKLLTK 287

Query: 162 VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 201
            + L  W G +  K + ++   G+     +  + +   GL
Sbjct: 288 -EQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGL 326


>M64590-1|AAA36463.1| 1020|Homo sapiens glycine decarboxylase
           protein.
          Length = 1020

 Score = 31.1 bits (67), Expect = 5.9
 Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 105 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
           KR S F+T +++NSYH    ++  ++K LEN ++  V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549


>M63635-1|AAA36478.1| 1020|Homo sapiens glycine decarboxylase
           protein.
          Length = 1020

 Score = 31.1 bits (67), Expect = 5.9
 Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 105 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
           KR S F+T +++NSYH    ++  ++K LEN ++  V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549


>D90239-1|BAA14286.1| 1020|Homo sapiens glycine decarboxylase
           precursor protein.
          Length = 1020

 Score = 31.1 bits (67), Expect = 5.9
 Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 105 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
           KR S F+T +++NSYH    ++  ++K LEN ++  V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549


>BC111995-1|AAI11996.1| 1020|Homo sapiens glycine dehydrogenase
           (decarboxylating) protein.
          Length = 1020

 Score = 31.1 bits (67), Expect = 5.9
 Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 105 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
           KR S F+T +++NSYH    ++  ++K LEN ++  V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549


>BC111993-1|AAI11994.1| 1020|Homo sapiens glycine dehydrogenase
           (decarboxylating) protein.
          Length = 1020

 Score = 31.1 bits (67), Expect = 5.9
 Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 105 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
           KR S F+T +++NSYH    ++  ++K LEN ++  V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549


>AL353718-2|CAH74116.1| 1036|Homo sapiens glycine dehydrogenase
           (decarboxylating) protein.
          Length = 1036

 Score = 31.1 bits (67), Expect = 5.9
 Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 105 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
           KR S F+T +++NSYH    ++  ++K LEN ++  V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549


>AL162411-3|CAH69992.1| 1036|Homo sapiens glycine dehydrogenase
           (decarboxylating) protein.
          Length = 1036

 Score = 31.1 bits (67), Expect = 5.9
 Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 105 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
           KR S F+T +++NSYH    ++  ++K LEN ++  V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549


>AF246134-1|AAK28443.2|  331|Homo sapiens glycine decarboxylase
           P-protein protein.
          Length = 331

 Score = 31.1 bits (67), Expect = 5.9
 Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 105 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 141
           KR S F+T +++NSYH    ++  ++K LEN ++  V
Sbjct: 276 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 311


>BC042420-1|AAH42420.2|  331|Homo sapiens aldo-keto reductase family
           7, member A3 (aflatoxin aldehyde reductase) protein.
          Length = 331

 Score = 30.7 bits (66), Expect = 7.7
 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 20/191 (10%)

Query: 65  TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 120
           T  AV  A LE G+T IDTA+ Y  G  + +   L  +      R  I      L+ +  
Sbjct: 27  TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86

Query: 121 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 180
           + + +   L  SL+ L    VDL+ +H P    ++ T ++     +T R      + G  
Sbjct: 87  KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137

Query: 181 KSIGISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 234
             +G+SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   A+
Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197

Query: 235 TPF-GSLFPSK 244
            P  G L   K
Sbjct: 198 NPLAGGLLTGK 208


>BC031562-1|AAH31562.1|  331|Homo sapiens aldo-keto reductase family
           7, member A3 (aflatoxin aldehyde reductase) protein.
          Length = 331

 Score = 30.7 bits (66), Expect = 7.7
 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 20/191 (10%)

Query: 65  TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 120
           T  AV  A LE G+T IDTA+ Y  G  + +   L  +      R  I      L+ +  
Sbjct: 27  TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86

Query: 121 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 180
           + + +   L  SL+ L    VDL+ +H P    ++ T ++     +T R      + G  
Sbjct: 87  KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137

Query: 181 KSIGISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 234
             +G+SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   A+
Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197

Query: 235 TPF-GSLFPSK 244
            P  G L   K
Sbjct: 198 NPLAGGLLTGK 208


>AJ271799-1|CAC81076.1|  331|Homo sapiens aflatoxin B1 aldehyde
           reductase 2 protein.
          Length = 331

 Score = 30.7 bits (66), Expect = 7.7
 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 20/191 (10%)

Query: 65  TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 120
           T  AV  A LE G+T IDTA+ Y  G  + +   L  +      R  I      L+ +  
Sbjct: 27  TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86

Query: 121 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 180
           + + +   L  SL+ L    VDL+ +H P    ++ T ++     +T R      + G  
Sbjct: 87  KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137

Query: 181 KSIGISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 234
             +G+SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   A+
Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197

Query: 235 TPF-GSLFPSK 244
            P  G L   K
Sbjct: 198 NPLAGGLLTGK 208


>AF040639-1|AAD02195.1|  331|Homo sapiens aflatoxin B1-aldehyde
           reductase protein.
          Length = 331

 Score = 30.7 bits (66), Expect = 7.7
 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 20/191 (10%)

Query: 65  TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 120
           T  AV  A LE G+T IDTA+ Y  G  + +   L  +      R  I      L+ +  
Sbjct: 27  TSAAVTRAFLERGHTEIDTAFVYSDGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86

Query: 121 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 180
           + + +   L  SL+ L    VDL+ +H P    ++ T ++     +T R      + G  
Sbjct: 87  KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137

Query: 181 KSIGISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 234
             +G+SN+   ++  I      +G   P+  Q   N   +Q   ELF   R   +   A+
Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197

Query: 235 TPF-GSLFPSK 244
            P  G L   K
Sbjct: 198 NPLAGGLLTGK 208


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.319    0.138    0.407 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 50,860,573
Number of Sequences: 224733
Number of extensions: 2088858
Number of successful extensions: 5247
Number of sequences better than 10.0: 152
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 4774
Number of HSP's gapped (non-prelim): 170
length of query: 340
length of database: 73,234,838
effective HSP length: 90
effective length of query: 250
effective length of database: 53,008,868
effective search space: 13252217000
effective search space used: 13252217000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 66 (30.7 bits)