Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001348-TA|BGIBMGA001348-PA|IPR001810|Cyclin-like F-box,
IPR006553|Leucine-rich repeat, cysteine-containing subtype,
IPR001395|Aldo/keto reductase
(595 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 458 e-127
UniRef50_Q96IG2 Cluster: F-box/LRR-repeat protein 20; n=63; Eume... 281 4e-74
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 259 2e-67
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 252 3e-65
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 248 4e-64
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 244 7e-63
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 243 1e-62
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 240 9e-62
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 238 3e-61
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 236 1e-60
UniRef50_P34284 Cluster: Uncharacterized F-box/LRR-repeat protei... 235 3e-60
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 234 4e-60
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 233 1e-59
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 230 9e-59
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 230 9e-59
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 228 3e-58
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 226 1e-57
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 226 1e-57
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 225 3e-57
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 225 3e-57
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 221 4e-56
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 219 1e-55
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 219 2e-55
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 216 2e-54
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 215 3e-54
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 213 1e-53
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 212 3e-53
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 210 8e-53
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 210 8e-53
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 207 6e-52
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 207 7e-52
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 206 2e-51
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 205 2e-51
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 204 4e-51
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 203 1e-50
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 201 4e-50
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 201 5e-50
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 199 1e-49
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 199 1e-49
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 199 2e-49
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 198 5e-49
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 197 6e-49
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 196 2e-48
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 195 2e-48
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 195 3e-48
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 194 7e-48
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 193 1e-47
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 193 1e-47
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 192 2e-47
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 192 3e-47
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 191 4e-47
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 191 5e-47
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 190 7e-47
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 190 9e-47
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 190 9e-47
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 190 9e-47
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 190 9e-47
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 190 1e-46
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 189 2e-46
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 189 2e-46
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 189 2e-46
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 188 3e-46
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 188 4e-46
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 188 4e-46
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 188 4e-46
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 188 5e-46
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 188 5e-46
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 188 5e-46
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 186 1e-45
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 186 1e-45
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 186 1e-45
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 186 1e-45
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 186 2e-45
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 185 3e-45
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 183 1e-44
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 182 2e-44
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 181 4e-44
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 180 7e-44
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 180 1e-43
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 180 1e-43
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 180 1e-43
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 179 2e-43
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 179 2e-43
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 179 2e-43
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 179 2e-43
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 179 2e-43
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 178 4e-43
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 177 5e-43
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 177 7e-43
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 176 2e-42
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 175 3e-42
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 175 3e-42
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 175 3e-42
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 175 4e-42
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 175 4e-42
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 175 4e-42
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 174 5e-42
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 174 6e-42
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 173 8e-42
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 173 1e-41
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 173 1e-41
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 172 3e-41
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 172 3e-41
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 172 3e-41
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 171 3e-41
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 171 4e-41
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 171 4e-41
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 171 6e-41
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 171 6e-41
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 171 6e-41
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 170 8e-41
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 170 8e-41
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 170 1e-40
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 170 1e-40
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 170 1e-40
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 169 2e-40
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 169 2e-40
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 169 2e-40
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 168 3e-40
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 168 3e-40
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 168 3e-40
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 168 4e-40
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 168 4e-40
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 168 4e-40
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 167 1e-39
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 167 1e-39
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 165 2e-39
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 165 2e-39
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 165 3e-39
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 165 3e-39
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 165 3e-39
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 165 4e-39
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 165 4e-39
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 165 4e-39
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 165 4e-39
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 164 5e-39
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 164 7e-39
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 164 7e-39
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 163 9e-39
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 163 9e-39
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 163 9e-39
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 163 9e-39
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 163 9e-39
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 163 1e-38
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 163 2e-38
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 163 2e-38
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 163 2e-38
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 162 2e-38
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 162 2e-38
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 162 2e-38
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 161 4e-38
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 161 4e-38
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 161 5e-38
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 161 5e-38
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 161 6e-38
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 160 8e-38
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 160 8e-38
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 159 1e-37
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 159 1e-37
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 159 1e-37
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 158 4e-37
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 158 4e-37
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 157 6e-37
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 157 6e-37
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 157 6e-37
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 157 8e-37
UniRef50_Q5C3P7 Cluster: SJCHGC05795 protein; n=1; Schistosoma j... 157 8e-37
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 155 3e-36
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 155 3e-36
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 155 3e-36
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 155 4e-36
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 155 4e-36
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 154 7e-36
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 153 1e-35
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 153 1e-35
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 153 1e-35
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 153 1e-35
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 153 2e-35
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 153 2e-35
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 152 2e-35
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 152 2e-35
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 152 2e-35
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 152 3e-35
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 151 4e-35
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 151 4e-35
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 151 4e-35
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 151 5e-35
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 151 7e-35
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 150 9e-35
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 150 9e-35
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 150 1e-34
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 149 2e-34
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 149 2e-34
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 149 2e-34
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 149 3e-34
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 149 3e-34
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 148 5e-34
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 147 6e-34
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 147 8e-34
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 146 1e-33
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 146 1e-33
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 146 1e-33
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 146 2e-33
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 146 2e-33
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 145 3e-33
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 145 3e-33
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 144 4e-33
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 144 4e-33
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 144 4e-33
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 144 8e-33
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 144 8e-33
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 143 1e-32
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 143 1e-32
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 143 1e-32
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 142 2e-32
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 141 4e-32
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 141 4e-32
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 141 5e-32
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 140 7e-32
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 140 1e-31
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 140 1e-31
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 139 2e-31
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 139 2e-31
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 139 2e-31
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 139 2e-31
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 139 2e-31
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 138 4e-31
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 138 5e-31
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 137 9e-31
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 136 2e-30
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 136 2e-30
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 136 2e-30
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 135 3e-30
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 135 3e-30
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 135 4e-30
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 134 5e-30
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 134 6e-30
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 134 6e-30
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 134 8e-30
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 132 3e-29
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 131 6e-29
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 130 8e-29
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 130 1e-28
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 130 1e-28
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 129 2e-28
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 129 2e-28
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 128 5e-28
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 127 1e-27
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 126 1e-27
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 126 1e-27
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 126 2e-27
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 126 2e-27
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 125 3e-27
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 124 5e-27
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 124 5e-27
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 124 7e-27
UniRef50_UPI0000D9A4C1 Cluster: PREDICTED: similar to F-box and ... 123 1e-26
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 123 1e-26
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 122 2e-26
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 122 3e-26
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 122 3e-26
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 122 4e-26
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 121 5e-26
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 119 2e-25
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 119 2e-25
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 119 3e-25
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 118 4e-25
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 117 1e-24
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 116 1e-24
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 116 2e-24
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 116 2e-24
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 116 2e-24
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 115 3e-24
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 115 4e-24
UniRef50_A1CF48 Cluster: F-box domain protein; n=5; Trichocomace... 114 5e-24
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 114 7e-24
UniRef50_Q0U0S4 Cluster: Putative uncharacterized protein; n=1; ... 114 7e-24
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 113 1e-23
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 113 2e-23
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 111 7e-23
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 111 7e-23
UniRef50_A7RK01 Cluster: Predicted protein; n=3; Nematostella ve... 110 9e-23
UniRef50_UPI000069E418 Cluster: F-box/LRR-repeat protein 13 (F-b... 110 1e-22
UniRef50_UPI000023F03D Cluster: hypothetical protein FG06969.1; ... 109 2e-22
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 109 2e-22
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 109 2e-22
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 109 3e-22
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 108 4e-22
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 107 6e-22
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 107 1e-21
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 107 1e-21
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 105 3e-21
UniRef50_UPI0000E475B6 Cluster: PREDICTED: hypothetical protein;... 105 4e-21
UniRef50_UPI0000ECD0F1 Cluster: F-box/LRR-repeat protein 13 (F-b... 105 4e-21
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 105 4e-21
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 104 6e-21
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 104 8e-21
UniRef50_Q4WI72 Cluster: F-box domain protein; n=3; Eurotiomycet... 104 8e-21
UniRef50_Q8AV18 Cluster: FBX13; n=2; Takifugu rubripes|Rep: FBX1... 103 1e-20
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 103 1e-20
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 103 2e-20
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 102 2e-20
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 101 4e-20
UniRef50_A7SBR5 Cluster: Predicted protein; n=1; Nematostella ve... 101 7e-20
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 100 9e-20
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 100 9e-20
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 100 1e-19
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 99 2e-19
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 98 5e-19
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 98 7e-19
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 97 9e-19
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 96 2e-18
UniRef50_UPI000069E417 Cluster: F-box/LRR-repeat protein 13 (F-b... 96 3e-18
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 96 3e-18
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 95 4e-18
UniRef50_UPI0000EBCDBB Cluster: PREDICTED: similar to F-box/LRR-... 95 6e-18
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 95 6e-18
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 94 1e-17
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 93 1e-17
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 93 2e-17
UniRef50_A6SL06 Cluster: Putative uncharacterized protein; n=2; ... 93 3e-17
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 92 3e-17
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 92 4e-17
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 91 6e-17
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 91 6e-17
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 91 6e-17
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 91 8e-17
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 91 1e-16
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 89 2e-16
UniRef50_A2UBY5 Cluster: Plant-metabolite dehydrogenase; n=1; Ba... 89 3e-16
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 88 5e-16
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 88 5e-16
UniRef50_UPI0000E81976 Cluster: PREDICTED: hypothetical protein;... 88 7e-16
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 88 7e-16
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 87 9e-16
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 87 9e-16
UniRef50_Q2R0L6 Cluster: Leucine Rich Repeat family protein, exp... 87 1e-15
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 87 2e-15
UniRef50_Q9UF56 Cluster: F-box/LRR-repeat protein 17; n=29; Eute... 87 2e-15
UniRef50_UPI0000586675 Cluster: PREDICTED: similar to ENSANGP000... 86 2e-15
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 86 2e-15
UniRef50_A7S506 Cluster: Predicted protein; n=1; Nematostella ve... 86 2e-15
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 85 4e-15
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 85 5e-15
UniRef50_Q9SKK0 Cluster: EIN3-binding F-box protein 1; n=3; rosi... 85 5e-15
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 85 7e-15
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 85 7e-15
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 84 9e-15
UniRef50_UPI0000E49968 Cluster: PREDICTED: similar to mKIAA0840 ... 84 1e-14
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 84 1e-14
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 83 2e-14
UniRef50_Q9VF10 Cluster: CG4221-PA; n=6; Endopterygota|Rep: CG42... 83 2e-14
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 83 3e-14
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 83 3e-14
UniRef50_Q2QNU9 Cluster: Leucine Rich Repeat family protein, exp... 83 3e-14
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 83 3e-14
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 82 5e-14
UniRef50_UPI0000DB79D5 Cluster: PREDICTED: similar to CG4221-PA;... 81 1e-13
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 80 1e-13
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 80 1e-13
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 80 1e-13
UniRef50_Q8LGK0 Cluster: F-box protein family, AtFBL4; n=4; core... 79 3e-13
UniRef50_A7QFH1 Cluster: Chromosome chr8 scaffold_88, whole geno... 79 3e-13
UniRef50_A7RXZ5 Cluster: Predicted protein; n=1; Nematostella ve... 79 3e-13
UniRef50_A7RLW1 Cluster: Predicted protein; n=1; Nematostella ve... 79 3e-13
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 79 3e-13
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 79 3e-13
UniRef50_A7QPZ2 Cluster: Chromosome undetermined scaffold_139, w... 79 4e-13
UniRef50_A7SG89 Cluster: Predicted protein; n=1; Nematostella ve... 79 4e-13
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 78 6e-13
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 78 6e-13
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 78 6e-13
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 78 8e-13
UniRef50_Q9FMW7 Cluster: Similarity to glucose regulated repress... 78 8e-13
UniRef50_Q2PQJ0 Cluster: EIN3-binding F-box protein 2; n=8; Magn... 78 8e-13
UniRef50_A7SMF7 Cluster: Predicted protein; n=1; Nematostella ve... 78 8e-13
UniRef50_A7RPT0 Cluster: Predicted protein; n=2; Nematostella ve... 78 8e-13
UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 78 8e-13
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 77 1e-12
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 77 1e-12
UniRef50_Q0IYY4 Cluster: Os10g0148800 protein; n=12; Oryza sativ... 77 1e-12
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 77 1e-12
UniRef50_Q5U201 Cluster: Protein AMN1 homolog; n=17; Deuterostom... 77 1e-12
UniRef50_A2X7L1 Cluster: Putative uncharacterized protein; n=1; ... 77 1e-12
UniRef50_A1SCW7 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 76 2e-12
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 76 2e-12
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 76 2e-12
UniRef50_Q9UJT9 Cluster: F-box/LRR-repeat protein 7; n=23; Eutel... 76 2e-12
UniRef50_UPI0001554EE1 Cluster: PREDICTED: hypothetical protein,... 76 3e-12
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 76 3e-12
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 76 3e-12
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 76 3e-12
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 75 4e-12
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 75 5e-12
UniRef50_Q8CDU4 Cluster: F-box/LRR-repeat protein 13; n=2; Mus m... 75 5e-12
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 75 7e-12
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 75 7e-12
UniRef50_O22161 Cluster: Protein ARABIDILLO-1; n=4; Magnoliophyt... 75 7e-12
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 74 9e-12
UniRef50_O49286 Cluster: F-box/LRR-repeat protein 5; n=9; Magnol... 74 9e-12
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 74 1e-11
UniRef50_Q54KC6 Cluster: Putative uncharacterized protein; n=1; ... 74 1e-11
UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 74 1e-11
UniRef50_Q8RWU5 Cluster: F-box/LRR-repeat protein 3; n=8; Magnol... 74 1e-11
UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n... 73 2e-11
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 73 2e-11
UniRef50_A7RRU9 Cluster: Predicted protein; n=1; Nematostella ve... 73 2e-11
UniRef50_Q9H469 Cluster: F-box only protein 37; n=29; Euteleosto... 73 2e-11
UniRef50_Q7VG62 Cluster: Aldo-keto reductase; n=2; Helicobacter|... 73 2e-11
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 73 2e-11
UniRef50_A7PW12 Cluster: Chromosome chr8 scaffold_34, whole geno... 73 2e-11
UniRef50_UPI0000F1F736 Cluster: PREDICTED: hypothetical protein;... 73 3e-11
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 73 3e-11
UniRef50_Q53LU3 Cluster: F-box protein family, AtFBL12, putative... 73 3e-11
UniRef50_Q8N1E6 Cluster: F-box/LRR-repeat protein 14; n=34; Eume... 73 3e-11
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 72 4e-11
UniRef50_Q16M79 Cluster: Putative uncharacterized protein; n=1; ... 72 4e-11
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 72 5e-11
UniRef50_Q86IU5 Cluster: Similar to Dictyostelium discoideum (Sl... 72 5e-11
UniRef50_Q1IPE6 Cluster: Aldo/keto reductase; n=21; Bacteria|Rep... 71 7e-11
UniRef50_A7S5H2 Cluster: Predicted protein; n=2; Nematostella ve... 71 7e-11
UniRef50_Q5KD68 Cluster: Ubiquitin-protein ligase, putative; n=1... 71 7e-11
UniRef50_Q4PEW4 Cluster: Putative uncharacterized protein; n=1; ... 71 7e-11
UniRef50_Q8NEE6 Cluster: F-box/LRR-repeat protein 13; n=28; Tetr... 71 7e-11
UniRef50_Q0P4D1 Cluster: Protein AMN1 homolog; n=1; Danio rerio|... 71 7e-11
UniRef50_UPI000065EBC1 Cluster: F-box/LRR-repeat protein 13 (F-b... 71 9e-11
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 71 9e-11
UniRef50_A5BIA4 Cluster: Putative uncharacterized protein; n=1; ... 71 9e-11
UniRef50_Q9SRR1 Cluster: F-box/LRR-repeat protein 12; n=1; Arabi... 71 9e-11
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 71 1e-10
UniRef50_Q8ZYV2 Cluster: Oxidoreductase, conjectural; n=3; Pyrob... 71 1e-10
UniRef50_Q9W214 Cluster: CG9952-PA; n=2; Sophophora|Rep: CG9952-... 70 2e-10
UniRef50_Q6CPC0 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 70 2e-10
UniRef50_Q8N1P0 Cluster: CDNA FLJ38068 fis, clone CTONG2015358; ... 70 2e-10
UniRef50_A1CZ15 Cluster: Cyclic nucleotide-binding domain protei... 70 2e-10
UniRef50_A7SSV9 Cluster: Predicted protein; n=1; Nematostella ve... 69 3e-10
UniRef50_Q8X0T7 Cluster: Related to protein GRR1; n=6; Pezizomyc... 69 3e-10
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 69 4e-10
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 69 4e-10
UniRef50_Q16Z82 Cluster: F-Box protein, putative; n=1; Aedes aeg... 69 4e-10
UniRef50_Q6C384 Cluster: Similar to DEHA0B08261g Debaryomyces ha... 69 4e-10
UniRef50_Q6BWV4 Cluster: Debaryomyces hansenii chromosome B of s... 69 4e-10
UniRef50_A6QS10 Cluster: Putative uncharacterized protein; n=1; ... 69 4e-10
UniRef50_A5DFW8 Cluster: Putative uncharacterized protein; n=1; ... 69 4e-10
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 69 5e-10
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 69 5e-10
UniRef50_A7SQL5 Cluster: Predicted protein; n=1; Nematostella ve... 68 6e-10
UniRef50_P25906 Cluster: Putative oxidoreductase ydbC; n=58; Bac... 68 6e-10
UniRef50_Q940J3 Cluster: Putative uncharacterized protein At3g58... 68 8e-10
UniRef50_Q54JI4 Cluster: Leucine-rich repeat-containing protein;... 68 8e-10
UniRef50_Q15I80 Cluster: SCF E3 ubiquitin ligase complex F-box p... 68 8e-10
UniRef50_Q6MD71 Cluster: Putative uncharacterized protein; n=1; ... 67 1e-09
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 67 1e-09
UniRef50_Q7K0V7 Cluster: LD27656p; n=2; Sophophora|Rep: LD27656p... 67 1e-09
UniRef50_A3LZH5 Cluster: Leucine rich repeat protein, contains F... 67 1e-09
UniRef50_Q8IY45 Cluster: Protein AMN1 homolog; n=4; Catarrhini|R... 67 1e-09
UniRef50_UPI00015B59FF Cluster: PREDICTED: similar to GA14916-PA... 67 1e-09
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 67 1e-09
UniRef50_A7SNI8 Cluster: Predicted protein; n=1; Nematostella ve... 67 1e-09
UniRef50_Q7SFH9 Cluster: Putative uncharacterized protein NCU086... 67 1e-09
UniRef50_A3LVS5 Cluster: Protein required for glucose repression... 67 1e-09
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 66 2e-09
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 66 2e-09
UniRef50_Q755X0 Cluster: AER398Wp; n=1; Eremothecium gossypii|Re... 66 2e-09
UniRef50_A4RP82 Cluster: Putative uncharacterized protein; n=1; ... 66 2e-09
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 66 2e-09
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 66 2e-09
UniRef50_A3DM42 Cluster: Aldo/keto reductase; n=1; Staphylotherm... 66 2e-09
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 66 2e-09
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 66 2e-09
UniRef50_A7T2M0 Cluster: Predicted protein; n=2; Nematostella ve... 66 2e-09
UniRef50_Q2HCN1 Cluster: Putative uncharacterized protein; n=1; ... 66 2e-09
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 66 2e-09
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 66 3e-09
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 66 3e-09
UniRef50_A7QYJ1 Cluster: Chromosome undetermined scaffold_248, w... 66 3e-09
UniRef50_Q9VFN3 Cluster: CG12402-PA; n=2; Sophophora|Rep: CG1240... 66 3e-09
UniRef50_A7S147 Cluster: Predicted protein; n=1; Nematostella ve... 66 3e-09
UniRef50_A6R4I1 Cluster: Predicted protein; n=1; Ajellomyces cap... 66 3e-09
UniRef50_UPI00015B4C0A Cluster: PREDICTED: similar to GA22149-PA... 65 4e-09
UniRef50_UPI0000F2B964 Cluster: PREDICTED: hypothetical protein;... 65 4e-09
UniRef50_Q0U911 Cluster: Putative uncharacterized protein; n=1; ... 65 4e-09
UniRef50_P24814 Cluster: SCF E3 ubiquitin ligase complex F-box p... 65 4e-09
UniRef50_UPI0000614B1A Cluster: Leucine-rich repeat-containing p... 65 6e-09
UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy... 65 6e-09
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 65 6e-09
UniRef50_Q6RZU4 Cluster: F-box-like protein; n=1; Musa acuminata... 65 6e-09
UniRef50_A7RFK9 Cluster: Predicted protein; n=1; Nematostella ve... 65 6e-09
UniRef50_Q0IEJ5 Cluster: F-box/lrr protein, putative; n=2; Culic... 64 8e-09
UniRef50_UPI0000E2097B Cluster: PREDICTED: S-phase kinase-associ... 64 1e-08
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 64 1e-08
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 64 1e-08
UniRef50_Q6CBX1 Cluster: Yarrowia lipolytica chromosome C of str... 64 1e-08
UniRef50_UPI0001556579 Cluster: PREDICTED: hypothetical protein;... 64 1e-08
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 64 1e-08
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 64 1e-08
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 64 1e-08
UniRef50_Q13309 Cluster: S-phase kinase-associated protein 2; n=... 64 1e-08
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 63 2e-08
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 63 2e-08
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 458 bits (1130), Expect = e-127
Identities = 210/344 (61%), Positives = 268/344 (77%), Gaps = 21/344 (6%)
Query: 18 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQAGLSSTELSFEAPGQQCGLFQNGVVKSKDK 77
++T++VP LKM N R+MPAI LGTYL G + G V SKDK
Sbjct: 17 SATIDVPMLKMLNDREMPAIALGTYL---------------------GFDKGGAVTSKDK 55
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
QLR+VVM+AID+GYRHFDTA++Y TE E+GEA++MK++EGV+KRED+F+TTKLWNT H+R
Sbjct: 56 QLRNVVMQAIDLGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKR 115
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGI 197
+VA A+ ++L K GLDY+DL+LMHWPI LN DYSHS+ D++ETWR E+ ++G K I
Sbjct: 116 EQVAVAMKETLNKTGLDYVDLFLMHWPIALNEDYSHSNTDYLETWRATEEMVKLGYTKSI 175
Query: 198 GLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVAR 257
GLSNFNK Q+ VL+E TIKP A+QIEVH Q +Q++++ + + EG++VMGYSPFGSLV R
Sbjct: 176 GLSNFNKLQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPFGSLVKR 235
Query: 258 HGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDF 317
G + GPK+DDPVL+S+A+KY KT QIVLRW ++RKVVPIPKTV+PKRL ENINIFDF
Sbjct: 236 FGMDLPGPKMDDPVLTSLAKKYEKTPAQIVLRWLVDRKVVPIPKTVSPKRLLENINIFDF 295
Query: 318 TLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFDKVDNPIADPF 361
L +E+EKIN F+++TRYTLPSFWQ HP+YPFD V NPI DPF
Sbjct: 296 KLKEEEIEKINQFNSNTRYTLPSFWQKHPFYPFDMVPNPIPDPF 339
>UniRef50_Q96IG2 Cluster: F-box/LRR-repeat protein 20; n=63;
Eumetazoa|Rep: F-box/LRR-repeat protein 20 - Homo
sapiens (Human)
Length = 436
Score = 281 bits (689), Expect = 4e-74
Identities = 122/189 (64%), Positives = 156/189 (82%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
F+N DE IN+KLPKELLLRI S+LDVV+LCRCAQVS+ WN+LALDGSNWQRIDLF+FQR
Sbjct: 16 FSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQR 75
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
D+EG V+ENIS+RCGGFLR+LSLRGC +GD +++T AQ+C NIE LNLN C K TD TC
Sbjct: 76 DIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATC 135
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
+L + CSKL+ ++L SC S++++SLKAL++GCPLL +N+SWC +T+ G++AL RGC
Sbjct: 136 TSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCG 195
Query: 547 KLKSFICKG 555
LK+ KG
Sbjct: 196 GLKALFLKG 204
Score = 91.9 bits (218), Expect = 4e-17
Identities = 56/186 (30%), Positives = 89/186 (47%), Gaps = 5/186 (2%)
Query: 372 ENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQ--RDVE 429
+ I ++ + + R +L +SL C V N L N + I++
Sbjct: 74 QRDIEGRVVENISKRCGGFLRKLSLRGCLGVGD--NALRTFAQNCRNIEVLNLNGCTKTT 131
Query: 430 GPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
++S+ C LR L L C SI + S+K L++ CP +E LN++ C ++T QAL
Sbjct: 132 DATCTSLSKFCSK-LRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQAL 190
Query: 490 GRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
R C L+ + L C + D +LK + CP L +N+ C IT+ G+ + RGC KL+
Sbjct: 191 VRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQ 250
Query: 550 SFICKG 555
S G
Sbjct: 251 SLCASG 256
Score = 88.6 bits (210), Expect = 4e-16
Identities = 42/117 (35%), Positives = 65/117 (55%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
I+ + + CGG L+ L L+GC + D ++K + CP + LNL C +ITD+ + R
Sbjct: 187 IQALVRGCGG-LKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRG 245
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C KLQ + C +++D L AL CP L + V+ C +T+ G LAR C +L+
Sbjct: 246 CHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELE 302
Score = 78.6 bits (185), Expect = 4e-13
Identities = 34/101 (33%), Positives = 58/101 (57%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+ L GC +I D + L Q+CP + L + +C ++TD L R C +L+K++L+
Sbjct: 249 LQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEE 308
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARG 544
C ++D +L L+ CP L +++S C+ IT+ G+ L G
Sbjct: 309 CVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNG 349
Score = 72.1 bits (169), Expect = 4e-11
Identities = 32/117 (27%), Positives = 64/117 (54%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
++ +S+ C L QL++ C+ + ++ L + C ++ L L C ++ D+ + +G
Sbjct: 161 LKALSEGCP-LLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAH 219
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +L +NL +C ++D L + GC L + S C +IT++ + AL + CP+L+
Sbjct: 220 CPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLR 276
Score = 69.7 bits (163), Expect = 2e-10
Identities = 49/162 (30%), Positives = 82/162 (50%), Gaps = 11/162 (6%)
Query: 395 SLCR--CAQVSKLWNILALDGSNWQRIDLFEFQR--DVEGPVIENISQRCGGFLRQLSLR 450
SLC C+ ++ IL G N R+ + E R + +++ C L ++ L
Sbjct: 251 SLCASGCSNITDA--ILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHE-LEKMDLE 307
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGR-RCS--KLQKINLDSCPSV 507
C I D ++ L+ CP ++ L+L+ C+ ITD + LG C+ +L+ I LD+CP +
Sbjct: 308 ECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLI 367
Query: 508 SDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+D SL+ L C L + + CQ IT +G++ L P +K
Sbjct: 368 TDASLEHL-KSCHSLERIELYDCQQITRAGIKRLRTHLPNIK 408
Score = 68.5 bits (160), Expect = 5e-10
Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 1/159 (0%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLR 450
L+ +++ C QV+K + G + + +E ++ I C + L+L+
Sbjct: 171 LEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVT-LNLQ 229
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDI 510
C I D + T+ + C ++ L + C ITD ALG+ C +L+ + + C ++D+
Sbjct: 230 TCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDV 289
Query: 511 SLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
LA C L +++ C IT+S + L+ CP+L+
Sbjct: 290 GFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQ 328
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 259 bits (634), Expect = 2e-67
Identities = 129/287 (44%), Positives = 184/287 (64%), Gaps = 13/287 (4%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
++ + V AID GYRHFD AS Y E EIG+A++ K+++GVVKRED+F+ TK+WN + ++
Sbjct: 32 EVENAVKLAIDAGYRHFDCASFYGNEAEIGKAIQEKIDQGVVKREDLFVVTKVWNDERKQ 91
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH-----------SDVDFMETWRGLE 186
V A SLKKLGL YIDLYL+HWP Y + +VD++ETWRG+E
Sbjct: 92 ELVVAACKRSLKKLGLGYIDLYLVHWPFSYPILYQYIVLPTYNAVTLDEVDYIETWRGME 151
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 246
+ ++G+ + IG+SNFN QQL R+L+ +IKP QIE+H+ QK++ EFC S+ + V
Sbjct: 152 ECIKLGLTRSIGVSNFNSQQLTRLLESASIKPVMNQIELHINLNQKKLREFCASKSIAVT 211
Query: 247 GYSPFGSLVARHGSTVEGPKI--DDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
GYSPFG+ + G I PV++ IA+KY KT QIVLR+ I+ +PIPK+ +
Sbjct: 212 GYSPFGAPGRNNVFQPAGADISLQSPVITGIAKKYNKTNAQIVLRYVIDIGAIPIPKSSS 271
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFD 351
KR++ENI+IFDF LTP+E+ I+ D R ++ YPF+
Sbjct: 272 EKRIKENIDIFDFKLTPEEIAAIDKLDCGFRTCSAIEHKDCKEYPFN 318
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 252 bits (616), Expect = 3e-65
Identities = 122/287 (42%), Positives = 173/287 (60%), Gaps = 14/287 (4%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G SK ++ + V AI+VGYRH DTA YE E+EIG A++ K+ +G +KREDIF+TTK
Sbjct: 20 GTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIREKINDGTIKREDIFVTTK 79
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA-----------DYSHSDVDF 178
LW H+ EV A SL+ LG DYIDL+L+HWP + SD D+
Sbjct: 80 LWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFKSGDALTPRDAAGKIEFSDTDY 139
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFC 238
+ETW+G+E+ +R G+ + IGLSNFN +Q+ R+L IKP Q+EV + QK ++EFC
Sbjct: 140 LETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKIKPVNNQVEVTMNLNQKPLIEFC 199
Query: 239 QSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVP 298
+ + V G+SP G RHG ++ D+P + +AQKY KT I R+ + V P
Sbjct: 200 KKHEITVTGFSPLGRPGNRHG--IQN-LWDEPQIQKLAQKYKKTPANIACRFIHQLGVTP 256
Query: 299 IPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNH 345
IPK+V R++EN++IFDF+LTP+EV I H +Y + + H
Sbjct: 257 IPKSVTKSRIKENLDIFDFSLTPEEVSTIEKMGKHNKYLILLYRYRH 303
Score = 240 bits (587), Expect = 9e-62
Identities = 116/269 (43%), Positives = 165/269 (61%), Gaps = 11/269 (4%)
Query: 91 YRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKK 150
YRH DTA +Y+ E+ IG A++ K+++G VKRED+F+TTKL H+ +EV A SL
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 151 LGLDYIDLYLMHWPI--------GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
LGLDYIDLYL+HWPI + SD D++ETW+G+E+ +R G+ + IG+SNF
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVSNF 420
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
N +Q+ R+L+ IKP Q+EV L+ QK ++EFC+ + V GYSP G R+G T
Sbjct: 421 NSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPLGRPGNRYGIT- 479
Query: 263 EGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPD 322
DDP++ + +KYGKT QI R+ + +PIPK+V R++EN IFDF+LT +
Sbjct: 480 --NAWDDPIIQELVKKYGKTPAQIACRFVSQLGAIPIPKSVTKSRIKENFEIFDFSLTDE 537
Query: 323 EVEKINGFDTHTRYTLPSFWQNHPYYPFD 351
E+ I T R + YYPF+
Sbjct: 538 EINSIQSIATGERVAPMEDAKESKYYPFN 566
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 248 bits (606), Expect = 4e-64
Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 21/312 (6%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VV 119
GQ+ L G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V
Sbjct: 11 GQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAV 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD 170
RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD
Sbjct: 71 PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNAD 130
Query: 171 YS--HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ + + ETW+ LE G+V+ +GLSNFN +Q++ +L +++P +Q+E H
Sbjct: 131 GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPY 190
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL 288
Q E++ CQ+ G+ V YSP GS E +++PV+ ++A+KYG++ QI+L
Sbjct: 191 LAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILL 250
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW------ 342
RWQ++RKV+ IPK++ P R+ +NI +FDFT +P+E++++N + + RY +P
Sbjct: 251 RWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRV 310
Query: 343 ---QNHPYYPFD 351
HP YPF+
Sbjct: 311 PRDAGHPLYPFN 322
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 244 bits (596), Expect = 7e-63
Identities = 109/254 (42%), Positives = 170/254 (66%), Gaps = 2/254 (0%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
++R V+ AI GYRH DTA++Y E+E+G+ + +++G+VKRE++F+TTKLWN +H R
Sbjct: 50 KVRQAVLWAIQAGYRHIDTAALYGNEEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGR 109
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGI 197
+V A+ +SL KLGL Y+DLYL+H P N + D+D + TW G+E+A+++G+ K I
Sbjct: 110 HQVVPALRESLTKLGLSYVDLYLIHSPEATNENGDPVDIDVLNTWNGMEEAKKLGLAKSI 169
Query: 198 GLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVAR 257
G+SNF+ L+R++ P QIEVH Q+++V G+ VM YSPFG V+R
Sbjct: 170 GVSNFDTALLDRLIAGSNTVPAVNQIEVHPSKTQEKLVADSHERGIEVMAYSPFGFYVSR 229
Query: 258 HGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDF 317
GS P +D ++ IA+KY KT Q+++R+ +ER ++PIPK+ N +R+ ENI++FDF
Sbjct: 230 -GSH-NNPVKNDRTVADIARKYNKTVNQVLVRYLLERSLIPIPKSTNQQRIRENIDVFDF 287
Query: 318 TLTPDEVEKINGFD 331
L+P+++ I D
Sbjct: 288 QLSPEDINAIGKLD 301
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 243 bits (594), Expect = 1e-62
Identities = 134/340 (39%), Positives = 199/340 (58%), Gaps = 20/340 (5%)
Query: 25 SLKMNNGRDMPAIGLGTYLGFDQAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDVVM 84
S+++++GR MP + GT+ F G S PG C ++G KS +R
Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQAN-----PGH-CAGTKHGTEKSFIDDVRVATK 61
Query: 85 RAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAI 144
A+D+GYRH D A +Y +E +G+A + K +G +KRED+F T+KLWNT H+ V A+
Sbjct: 62 MALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPAL 121
Query: 145 NDSLKKLGLDYIDLYLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGI 193
+L L +DY+DLYL+H P+ N D + D ++TW+ LE+ + G+
Sbjct: 122 EKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGL 181
Query: 194 VKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 251
VK IG+SNFN++QLE +L K G KP QIE H QK+M+EFC+S+ +VV+ Y
Sbjct: 182 VKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAYGVL 241
Query: 252 GSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEE 310
GS A P ++DPVL SI QKY K+ Q+ +R+ I+R V I K+ NP R+++
Sbjct: 242 GSPGAGKWVDQSCPILLEDPVLISIGQKYSKSPAQVSMRYMIQRGCVAIAKSFNPDRMKQ 301
Query: 311 NINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
N+ +FDF L+ +E+ I+G + + RY S W+ HP YPF
Sbjct: 302 NLEVFDFQLSQEEMAAIDGLNKNMRYWSFSEWEKHPQYPF 341
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 240 bits (587), Expect = 9e-62
Identities = 120/299 (40%), Positives = 177/299 (59%), Gaps = 17/299 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G SK + VM AID G+RH DTA Y E +G A++ K+EEGVV RE++F+TTK
Sbjct: 23 GTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRAKIEEGVVTREELFVTTK 82
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------------NADYSHS 174
LWNT H V A SL+ LGLDY+DL+L+H P G N + S
Sbjct: 83 LWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNGWDPEKRTPLDDNGNVLCS 142
Query: 175 DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEM 234
D D+++TW+ +E G V IG+SNFN +QLER+L +KP Q+E + QK +
Sbjct: 143 DDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILANCRVKPVTNQVECSARINQKLL 202
Query: 235 VEFCQSEGVVVMGYSPFGS--LVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQI 292
+EFC +VV +SPFG L ++ P +D+P + I +K+ K++ Q+VLR+ +
Sbjct: 203 IEFCMERDIVVTAHSPFGRPHLFEKNPKDKPKPVLDEPEIVEIGKKFDKSSAQVVLRYLL 262
Query: 293 ERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFD 351
+ VVPIPK+ + + L++N+ IFDF L+ D++ ++GF+T+ R S + H YYPF+
Sbjct: 263 QNGVVPIPKSTSAQHLKQNLEIFDFELSSDDMAILDGFNTNQRMVRLSLLKEHKYYPFN 321
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 238 bits (582), Expect = 3e-61
Identities = 125/310 (40%), Positives = 189/310 (60%), Gaps = 25/310 (8%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G + + G ++ Q ++V +AID+GYRH DTA +YE E EIG+A++ K+ EGV++
Sbjct: 13 GYEIPVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQAIRDKIAEGVIR 72
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN-ADYSH------ 173
RED+F+TTKLWNT H V +A S L + YIDL+LMH P+G+ + Y +
Sbjct: 73 REDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGVQFSGYEYADMQPK 132
Query: 174 --------SDVDFMETWRGLED-AQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIE 224
SDVD++ETW+ +E G V+ IGLSNFN +Q+ER+L+ T+KP Q+E
Sbjct: 133 DAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERILQIATVKPVNNQVE 192
Query: 225 VHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPK--IDDPVLSSIAQKYGKT 282
+ Q++++ FCQ+ G+ V Y P G R T G + +DDP + I +KYGKT
Sbjct: 193 ANPGYDQRKLIAFCQARGITVTAYGPMG----RPHRTTNGNRNALDDPKVLEIGRKYGKT 248
Query: 283 TPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSF- 341
Q++LR+ I+ +PIP + N +R+ +NI++ DF LT +E+E + F H+ T+P
Sbjct: 249 GGQVILRYLIDIGTIPIPYSTNEERMRQNIDVCDFKLTGEEIEYLASF--HSARTIPFLP 306
Query: 342 WQNHPYYPFD 351
++H YYPFD
Sbjct: 307 LKSHKYYPFD 316
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 236 bits (578), Expect = 1e-60
Identities = 122/304 (40%), Positives = 179/304 (58%), Gaps = 14/304 (4%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G +F G S Q+ V AIDVGYRH D A VY+ E E+GE + K+ EGVVK
Sbjct: 14 GNSIPMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAAKIAEGVVK 73
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG---------LNAD- 170
RED+F+T+KLWNT HR V A +L+ L LDY+DLYL+HWP+G + D
Sbjct: 74 REDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTELFPMGPDG 133
Query: 171 --YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ SD D+++TW +E G+V+ IG+SNFN +Q++RVL I P QIE H
Sbjct: 134 KTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPATNQIECHPY 193
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKI-DDPVLSSIAQKYGKTTPQIV 287
Q ++ FC +G++V YSP GS AR + P + DD + +A+K+GK+ QI+
Sbjct: 194 LHQSKITTFCAEKGIIVTAYSPLGS-PARPWVKADDPVLMDDATVGQLAKKHGKSAAQIL 252
Query: 288 LRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPY 347
+R+QI+ V IPK+V +R+ N ++F F L D+++++ G + + R S HP+
Sbjct: 253 IRYQIQLGHVVIPKSVTKERIASNFDVFSFQLDEDDMKQLAGLERNGRICPESSAFGHPH 312
Query: 348 YPFD 351
+PF+
Sbjct: 313 HPFE 316
>UniRef50_P34284 Cluster: Uncharacterized F-box/LRR-repeat protein
C02F5.7; n=3; Caenorhabditis|Rep: Uncharacterized
F-box/LRR-repeat protein C02F5.7 - Caenorhabditis
elegans
Length = 466
Score = 235 bits (574), Expect = 3e-60
Identities = 95/185 (51%), Positives = 142/185 (76%)
Query: 371 DENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEG 430
D + INR LPKE+LL++ S+LD +LCR AQV + W+ILALDGSNWQR+DLF FQRDV+
Sbjct: 52 DNSLINRVLPKEVLLKVFSFLDTKALCRSAQVCRSWSILALDGSNWQRVDLFTFQRDVKT 111
Query: 431 PVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALG 490
V+EN+++RCGGFL++LSL+GCE++ D +++T CPN+E L+L +CK++TD +C+ LG
Sbjct: 112 AVVENLARRCGGFLKELSLKGCENVHDSALRTFTSRCPNLEHLSLYRCKRVTDASCENLG 171
Query: 491 RRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
R C KL +NL++C S++D ++K + DGCP L+++N+SWC +I + GV+ + C L +
Sbjct: 172 RYCHKLNYLNLENCSSITDRAMKYIGDGCPNLSYLNISWCDAIQDRGVQIILSNCKSLDT 231
Query: 551 FICKG 555
I +G
Sbjct: 232 LILRG 236
Score = 67.7 bits (158), Expect = 8e-10
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
++NI+ L L + C I D S+ +L Q N++ L L+ C + D L R
Sbjct: 271 VQNIANGATA-LEYLCMSNCNQISDRSLVSLGQHSHNLKVLELSGCTLLGDNGFIPLARG 329
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
C +L++++++ C +SD ++ +LA+ C L +++S C+ IT+ ++ LA
Sbjct: 330 CRQLERLDMEDCSLISDHTINSLANNCTALRELSLSHCELITDESIQNLA 379
Score = 63.7 bits (148), Expect = 1e-08
Identities = 37/139 (26%), Positives = 67/139 (48%), Gaps = 3/139 (2%)
Query: 415 NWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLN 474
N + + L+ +R V EN+ + C L L+L C SI D +MK + CPN+ LN
Sbjct: 150 NLEHLSLYRCKR-VTDASCENLGRYCHK-LNYLNLENCSSITDRAMKYIGDGCPNLSYLN 207
Query: 475 LNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSIT 534
++ C I D+ Q + C L + L C +++ ++ + +N+ C +T
Sbjct: 208 ISWCDAIQDRGVQIILSNCKSLDTLILRGCEGLTENVFGSVEAHMGAIKKLNLLQCFQLT 267
Query: 535 ESGVEALARGCPKLKSFIC 553
+ V+ +A G L+ ++C
Sbjct: 268 DITVQNIANGATALE-YLC 285
Score = 60.1 bits (139), Expect = 2e-07
Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 10/165 (6%)
Query: 388 LSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS---QRCGGFL 444
LSYL++ S C Q + IL SN + +D R EG + EN+ + G +
Sbjct: 203 LSYLNI-SWCDAIQDRGVQIIL----SNCKSLDTL-ILRGCEG-LTENVFGSVEAHMGAI 255
Query: 445 RQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSC 504
++L+L C + D +++ +A +E L ++ C +I+D++ +LG+ L+ + L C
Sbjct: 256 KKLNLLQCFQLTDITVQNIANGATALEYLCMSNCNQISDRSLVSLGQHSHNLKVLELSGC 315
Query: 505 PSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+ D LA GC L +++ C I++ + +LA C L+
Sbjct: 316 TLLGDNGFIPLARGCRQLERLDMEDCSLISDHTINSLANNCTALR 360
Score = 60.1 bits (139), Expect = 2e-07
Identities = 29/107 (27%), Positives = 59/107 (55%), Gaps = 2/107 (1%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSK-LQKINLD 502
L +L + C I D ++ +LA +C + +L+L+ C+ ITD++ Q L + + L + LD
Sbjct: 333 LERLDMEDCSLISDHTINSLANNCTALRELSLSHCELITDESIQNLASKHRETLNVLELD 392
Query: 503 SCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+CP ++D +L L C L +++ CQ++++ + P ++
Sbjct: 393 NCPQLTDSTLSHLRH-CKALKRIDLYDCQNVSKEAIVRFQHHRPNIE 438
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 234 bits (573), Expect = 4e-60
Identities = 116/294 (39%), Positives = 179/294 (60%), Gaps = 13/294 (4%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G +SK ++ + A+ GYRH D A VY+ ++E+GEA+K ++EG VKRE++FIT+K
Sbjct: 19 GTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDEGKVKREELFITSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW-----------PIGLNADYSHSDVDF 178
+WNT H + + I+ L L L Y+DL L+HW P G N +SDVD+
Sbjct: 79 VWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAELFPAGENGKMRYSDVDY 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFC 238
+ETW+ E AQ+ G + IGLSNF Q++RV +KP +Q+E+H Q ++ EFC
Sbjct: 139 LETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELHPYFTQVKLREFC 198
Query: 239 QSEGVVVMGYSPFGSLVARHGSTVEGPKI-DDPVLSSIAQKYGKTTPQIVLRWQIERKVV 297
+ +G+VV+GYSP G+ + P + + V++ IA+ +GKT QI+LRW ++ +
Sbjct: 199 KEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNEVVAGIAKAHGKTPAQIILRWFVDSGLS 258
Query: 298 PIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYT-LPSFWQNHPYYPF 350
IPK+V P+R+ EN+ +FDF LT +E+ KI+G + + R L +HP+ PF
Sbjct: 259 AIPKSVTPQRISENLAVFDFQLTAEEISKIDGINKNWRIVDLSQRDGDHPHCPF 312
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 233 bits (570), Expect = 1e-59
Identities = 124/295 (42%), Positives = 180/295 (61%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AID+GYRH D A VY+ E+E+G A++ K++E VVKR+D+FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADY---------SHSDVDF 178
LW T H ++ V A +L L LDY+DLYL+HWP G DY SD DF
Sbjct: 79 LWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDF 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E G+VK IG+SNFN Q+ER+L K G KP QIE H Q++++E
Sbjct: 139 VDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIE 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+C S+G+VV YSP GS R + E P ++DP + +IA KY KTT Q+++R+ I+R
Sbjct: 199 YCHSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P R+ EN+ +FDF ++ +++ + ++ + R H YPF
Sbjct: 258 LVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNRNWRVCALMSCAKHKDYPF 312
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 230 bits (562), Expect = 9e-59
Identities = 111/313 (35%), Positives = 182/313 (58%), Gaps = 13/313 (4%)
Query: 52 STELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK 111
ST + G+ + G +S + + V AID+GYRHFD A +Y E +G A++
Sbjct: 2 STPSFLLSSGRNMPMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIR 61
Query: 112 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY 171
K++EG+V R+++FIT+KLWNT H+ V A SL+ LG+DY+DLYLMHWP+ +
Sbjct: 62 EKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGD 121
Query: 172 S------------HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPD 219
+ D+D+++TW+ +ED G+V IG+SNFN++Q+ R+L +KP
Sbjct: 122 NLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAKLKPV 181
Query: 220 AIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKY 279
+QIE H QK ++ C + V YS GS + P + +P++ S+A+KY
Sbjct: 182 MLQIECHPYLRQKSLITLCYDNAIGVTAYSSLGSGHTPYEKPGSYPLLQNPIIVSVAEKY 241
Query: 280 GKTTPQIVLRWQIERKVVPIPKTVNPKRLEENI-NIFDFTLTPDEVEKINGFDTHTRYTL 338
G+T Q++LR+Q + ++ IP++V+ + + +N I+DF L D+V+ I+G D + R+
Sbjct: 242 GRTPAQVLLRYQTQSGIIVIPRSVSKQHMHDNFKRIWDFQLAIDDVKAIDGLDCNGRFMT 301
Query: 339 PSFWQNHPYYPFD 351
HP++PF+
Sbjct: 302 MKAAYGHPHHPFE 314
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 230 bits (562), Expect = 9e-59
Identities = 117/290 (40%), Positives = 183/290 (63%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + A+DVGYRH DTA Y+ E+EIG+A++ K++ GVVKRED+FITTKLW T
Sbjct: 31 KSKSLEAACL-ALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVVKREDLFITTKLWCTC 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA---DYSHSD--------VDFMETWR 183
R V A+ SLKKL LDY+DLY+MH+P+ + + D+ ++ VDF +TW
Sbjct: 90 FRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
LE+ + G+VK IG+SNFN +QLER+L K G KP Q+E HL Q++++++C+S+
Sbjct: 150 RLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ Y G+ + P ++DPVL +A+K ++ I LR+ I+R +VP+
Sbjct: 210 DIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLIQRGIVPLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
++ + EN+ +F F L+P++++ ++G + + RY F +HP YPF
Sbjct: 270 QSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFRYLPAEFLVDHPEYPF 319
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 228 bits (558), Expect = 3e-58
Identities = 115/285 (40%), Positives = 167/285 (58%), Gaps = 14/285 (4%)
Query: 54 ELSFEAP-GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKM 112
++S P G L G K K ++ + A+D GYRHFD A +Y E+E+G A++
Sbjct: 2 DMSVTLPSGHAMPLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALRE 61
Query: 113 KVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----- 167
++ +KRED+FITTK+WNT H + +VA+ N SL L LDYIDLY+MHWP+G
Sbjct: 62 AMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGP 121
Query: 168 --------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPD 219
D +SDV ++ETW +ED + G K +GLSNFN +QL+ VL+ T+ P
Sbjct: 122 TVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPS 181
Query: 220 AIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKY 279
+Q+E H Q E++ FC+ VVV YSP G + E DDP L IAQ+
Sbjct: 182 VLQVESHPFLPQVELLNFCRERSVVVSAYSPLGCGDRAWKLSGEPSIFDDPGLLKIAQRL 241
Query: 280 GKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEV 324
K+ Q+ +R+Q++R + IPK+ P ++ENIN+FDF L+ D++
Sbjct: 242 RKSIAQVAIRFQVQRGIPVIPKSATPSHIQENINVFDFELSEDDM 286
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 226 bits (552), Expect = 1e-57
Identities = 118/290 (40%), Positives = 167/290 (57%), Gaps = 11/290 (3%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS + A+DVGYRH DTA VYE E E+G+A+ K+ EGVV RE++F+TTK
Sbjct: 22 GTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAEGVVTREEVFVTTK 81
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG--------LNADYSHSDVDFMET 181
L H V +A SL LGL+Y+DLYLMH P+G ++ +DVD+++T
Sbjct: 82 LGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHNDSNVHGTLELTDVDYLDT 141
Query: 182 WRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSE 241
WR +E +G+ + IGLSNFN Q ERVL I+P Q+E H Q+++ E +
Sbjct: 142 WREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLREHAKRH 201
Query: 242 GVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPK 301
G+V+ Y P L + P + D ++A+KYG+TT QI LR+ ++ VVP+PK
Sbjct: 202 GLVICAYCP---LARPQPARQWPPFLYDEHAQNLAKKYGRTTAQICLRYLVQLGVVPLPK 258
Query: 302 TVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFD 351
+ N R+EEN +FDF L+PD+V + + T R S H YYPF+
Sbjct: 259 SSNKARIEENFRVFDFELSPDDVAGMEQYHTGQRTVPFSGMSGHKYYPFN 308
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 226 bits (552), Expect = 1e-57
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 225 bits (550), Expect = 3e-57
Identities = 107/281 (38%), Positives = 170/281 (60%), Gaps = 14/281 (4%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
AIDVGYRH D A +Y E+E+G A++ K+ +G VKRED+F T KLW+T H V A+
Sbjct: 42 AIDVGYRHIDCAFLYGNEEEVGRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALE 101
Query: 146 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 194
SLK L LDY+DL+++H P+ N + + + D +TW+ LE + G+V
Sbjct: 102 KSLKDLQLDYMDLFIIHMPMEFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLV 161
Query: 195 KGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
+ IG+SNFN +QLE +L + KP Q+E H+ Q +++EFC+S+ +V++GYS G
Sbjct: 162 RSIGVSNFNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLG 221
Query: 253 SLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
S P ++DP L+ IA+K+ +T Q+ +R+ ++R VV + K+ P R+++N
Sbjct: 222 SSRDERWIEASTPVLLEDPALTEIAKKHNRTPAQVAMRYHLQRGVVVLAKSFTPARIQQN 281
Query: 312 INIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFDK 352
+FDF L +++ I+G + + RY S W +HP YP+ +
Sbjct: 282 FQVFDFQLDAEDMRSIDGLNRNMRYIDTSRWSDHPKYPYSE 322
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 225 bits (550), Expect = 3e-57
Identities = 109/279 (39%), Positives = 175/279 (62%), Gaps = 14/279 (5%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
AIDVG+ H D + +Y+ E+EIG+A+ K+E+G VKREDIF T+KLW+T HR V ++
Sbjct: 41 AIDVGFCHIDCSHLYQNEEEIGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLE 100
Query: 146 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 194
+SL+KL LDY+DLYL+H+P+ L + + VD +TW +E + G+
Sbjct: 101 NSLRKLNLDYVDLYLIHFPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLA 160
Query: 195 KGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
K IG+SNFN++QLE +L K G KP Q+E HL Q +++ +C+ +V++ Y G
Sbjct: 161 KSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALG 220
Query: 253 SLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
+ ++ + P +DDPVL ++A+KY +T I LR+Q++R +V + K+ N +R+ EN
Sbjct: 221 TQRYKYCINEDTPVLLDDPVLCAMAKKYKRTPALIALRYQLDRGIVALAKSFNEERIREN 280
Query: 312 INIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+ +FDF L D+++ ++G D + RY ++ HP +PF
Sbjct: 281 MQVFDFQLASDDMKILDGLDRNLRYFPADMFKAHPNFPF 319
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 221 bits (540), Expect = 4e-56
Identities = 109/312 (34%), Positives = 179/312 (57%), Gaps = 17/312 (5%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G+ + G +S + + V AID+GYRHFD A +Y E ++G A++ K++EGVV
Sbjct: 11 GKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVT 70
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH------- 173
R+++FIT+KLWNT H+ V A S++ LG+ Y++LYLMHWP+ + +
Sbjct: 71 RDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPD 130
Query: 174 ------SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHL 227
D+D+++TWR +E+ G+ + IG+SNFN+QQ+ R+L +KP +QIE H
Sbjct: 131 TNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHP 190
Query: 228 QNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIV 287
QK ++ C + V YS GS + P + P + +IA+KY +T Q++
Sbjct: 191 YLSQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVL 250
Query: 288 LRWQIERKVVPIPKTVNPKRLEENI-NIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHP 346
LR+Q + ++ IP++V+ + + +N I+DF L D+++ IN D + R+ HP
Sbjct: 251 LRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHP 310
Query: 347 YYPFD---KVDN 355
++PF+ KVDN
Sbjct: 311 HHPFEPKAKVDN 322
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 219 bits (536), Expect = 1e-55
Identities = 111/280 (39%), Positives = 170/280 (60%), Gaps = 15/280 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS ++R+ V AID GYRH D A VY+ E E+GEA++ K++E VKRED+FI +K
Sbjct: 19 GTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQEKAVKREDLFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA-----------DYSHSDVDF 178
LW+T ++ V +A ++L L LDY+DLYL+HWP G + S F
Sbjct: 79 LWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLPTDDKGSILSSKYTF 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHLQNVQKEMVE 236
++ W +E+ G+VK +G+SNFN Q+ER+L + + KP Q+E H Q+++ +
Sbjct: 139 LDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLTQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+C S+G+ + YSP GS R + E P ++ P + IA K+ KT Q+++R+ IER
Sbjct: 199 YCHSKGITITAYSPLGS-PDRPSAKPEDPLLLEIPKIKEIAAKHKKTAAQVLIRFHIERN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR 335
VV IPK+V P R++ENI +FDF L+ +++ I F+ + R
Sbjct: 258 VVVIPKSVTPSRIQENIQVFDFQLSEEDMAAILSFNRNWR 297
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 219 bits (535), Expect = 2e-55
Identities = 106/279 (37%), Positives = 159/279 (56%), Gaps = 19/279 (6%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
D+V AI GYRH D A +Y E+E+GE ++ +++GVVKRED+F+T+KLWNT H + +V
Sbjct: 29 DLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDV 88
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPI----GLNADYSHSD-------VDFMETWRGLEDAQ 189
A +L LGLDY+DLYL+HW + G N + D + ETW+ +E+
Sbjct: 89 GVACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEPLDDDGVAKFSFISMKETWQAMEELV 148
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G+VK +G++NF L +L IKP QIE+H Q ++V FC S+ + V YS
Sbjct: 149 EQGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYS 208
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
PFGS E P + DP + +A+ GKT Q++LRW ++R IP++ N R++
Sbjct: 209 PFGS--------TEAPVLTDPTVKEVAKGLGKTPAQVLLRWAVQRNTSVIPRSSNATRIK 260
Query: 310 ENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYY 348
EN I F L+ + + +N + + R+ P W PY+
Sbjct: 261 ENFEIATFELSNEHMAALNTLNRNKRFVNPIEWWGFPYF 299
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 216 bits (527), Expect = 2e-54
Identities = 112/267 (41%), Positives = 163/267 (61%), Gaps = 22/267 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV K ++++ + V A+ VGYR DTA +YE E +G A+K + + REDIF+TTK
Sbjct: 18 GVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRALK----DSGIPREDIFLTTK 73
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVD-FMETWRGLEDA 188
+WN A SL+KLG+DY+DLYL+HWP+ D D +M+TWR LE
Sbjct: 74 VWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM--------PDEDLYMDTWRALEQL 125
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
R G K IG+SNF+ L RVL+EGT+ P QIE+H Q+ + FCQ G+VV +
Sbjct: 126 YRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVVEAW 185
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SP + R T DPV++ IA ++GKT Q+VLRW ++ ++ IPK+V P R+
Sbjct: 186 SPL--MKGRDALT-------DPVITDIAARHGKTPAQVVLRWHLQHDIIAIPKSVTPSRI 236
Query: 309 EENINIFDFTLTPDEVEKINGFDTHTR 335
+EN++IFDF L+PD++ +I+ + + R
Sbjct: 237 QENLDIFDFVLSPDDMRQIDQLNRNER 263
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 215 bits (525), Expect = 3e-54
Identities = 108/279 (38%), Positives = 165/279 (59%), Gaps = 14/279 (5%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
AID GYRH D A +Y+ E E+GEA++ K+ EG V+REDIF KLW T H V +
Sbjct: 44 AIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLE 103
Query: 146 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 194
+L+ L LDY+DLY++ P+ N + + + TW +E + G+V
Sbjct: 104 RTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLV 163
Query: 195 KGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
K +G+SNFN++QLE +L + + KP + Q+E H Q ++++FCQ +V+ YSP G
Sbjct: 164 KSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
Query: 253 SLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
+ V P + D +L+S+ ++Y KT QIVLR+ I+R VV IPK+ N +R++EN
Sbjct: 224 TSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKEN 283
Query: 312 INIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
IFDF+LT +E++ I + + R+ W++HP YPF
Sbjct: 284 FQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPF 322
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 213 bits (519), Expect = 1e-53
Identities = 111/278 (39%), Positives = 165/278 (59%), Gaps = 18/278 (6%)
Query: 74 SKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNT 133
SK Q+ V AID GYRH D A VY E E+G +K K + VVKREDIFIT+KLWN
Sbjct: 7 SKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNN 66
Query: 134 QHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGI 193
+H +V QA + +LK L L Y+DLYLMHWP+ A +E G
Sbjct: 67 KHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAYQA---------------MEKLVTSGK 111
Query: 194 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 253
K IGLSNF+ + ++RV+++ TI+P +Q+E+H Q++++EFC+ + V YSP G+
Sbjct: 112 CKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSPLGA 171
Query: 254 LVARHGSTVEGPKI-DDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENI 312
R + PK+ +DP+++ IA K GK+ QI++R+ +ER ++ IPK+V P R++ N
Sbjct: 172 -PDRPWVKDDDPKLMEDPIVTGIATKKGKSPAQILIRFCLERGIICIPKSVTPSRIQANF 230
Query: 313 NIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+F L P++++ + + R L W NHP +PF
Sbjct: 231 EALNFELDPEDLKTLLAMNIGYRGCLLD-WVNHPQHPF 267
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 212 bits (517), Expect = 3e-53
Identities = 99/280 (35%), Positives = 168/280 (60%), Gaps = 15/280 (5%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
AI GYRH DTA Y E ++G A++ K+++G+++R+D+FI +KLW T H ++ N
Sbjct: 9 AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFN 68
Query: 146 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 194
SL L LDY+D YL+H+P+GL + +D+D+++ WRG+E + G V
Sbjct: 69 KSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATGKV 128
Query: 195 KGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS- 253
K IG+SNF +Q++R+L I P Q+E+H VQ +++++C+S+ + + +SPFGS
Sbjct: 129 KSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAHSPFGSP 188
Query: 254 ---LVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEE 310
L + G ++DPV+ +A+K+ +T Q++LR+ I++ + IPK+V P + E
Sbjct: 189 GRPLEFQTGDEDPMGLLEDPVVVDVARKHRRTPAQVLLRYHIQQDIAVIPKSVKPHHILE 248
Query: 311 NINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
N IFDFTL +++ + + R + + + H +YPF
Sbjct: 249 NTKIFDFTLDEEDMNALKSLNRGWRACIITELEAHYFYPF 288
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 210 bits (513), Expect = 8e-53
Identities = 103/294 (35%), Positives = 172/294 (58%), Gaps = 12/294 (4%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G + L G KS+ +Q+ V AI +GYRH D AS+Y E+E+G+A++ ++ +
Sbjct: 27 GDRMPLLGLGTGKSESRQVYKSVREAIKIGYRHIDCASIYGNEEEVGDAIRDAIQNHEIT 86
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSD-VD-- 177
R +++IT+KLW+ H + V A++ SL+ LG+DY++LYL+HWP+G+ + + ++ VD
Sbjct: 87 RSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPEKTFAESVDDL 146
Query: 178 -------FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNV 230
ETW +E + G+ K IG+SNF ++L++++ KP+ Q+E H
Sbjct: 147 LTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQKPEVNQVEHHPLLQ 206
Query: 231 QKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV-EGPKI-DDPVLSSIAQKYGKTTPQIVL 288
Q ++E+C SE +++ YSP GS+ V + P + D PV+ +IA+ G + Q+VL
Sbjct: 207 QPTLIEYCASEEILITAYSPLGSMDRPQSLKVKDAPAVLDHPVIRAIAETRGCSPAQVVL 266
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW 342
W ++R + IPK+V P RL EN+ D L+ E++KI D + R +FW
Sbjct: 267 AWDVQRGISAIPKSVKPSRLLENLQAADIQLSNTELQKIEALDQNFRLVNGAFW 320
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 210 bits (513), Expect = 8e-53
Identities = 107/286 (37%), Positives = 166/286 (58%), Gaps = 17/286 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G+ + + +L++V++ AI +GYRHFD A+ Y++E ++GEA+ + G+VKRE++FITTK
Sbjct: 18 GLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFKTGLVKREELFITTK 77
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-------IGLNADYSHSD------- 175
+WN+ H V +A +SL+KL +DY+DLYL+H+P IG A D
Sbjct: 78 IWNSDHGH--VVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTASLLGEDKVLDIDV 135
Query: 176 -VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEM 234
+ +TW G+E +G+V+ IGLSN+ L IKP Q E H + +
Sbjct: 136 TISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSL 195
Query: 235 VEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIER 294
V+FC GV+ ++P G A +DDPVL+ +A+KYGK+ QI LRW I+R
Sbjct: 196 VKFCMKHGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVAKKYGKSVAQICLRWGIQR 255
Query: 295 KVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPS 340
K IPK+ +RL+EN+ + +F L+ ++++ I D R +LPS
Sbjct: 256 KTAVIPKSSKIQRLKENLEVLEFQLSDEDMQLIYSIDRKYRTSLPS 301
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 207 bits (506), Expect = 6e-52
Identities = 107/306 (34%), Positives = 180/306 (58%), Gaps = 15/306 (4%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G++ L G + K +++ V+ AID GYRH D AS+Y E+ +G+ +K K+++G +K
Sbjct: 13 GRKLPLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIKAKIDDGTIK 72
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---IGLNADYSHSD-- 175
RED+F+T+KLW T + V + SL LGL Y+DL+L+H P +G + D
Sbjct: 73 REDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFPMDDNG 132
Query: 176 -------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDA-IQIEVHL 227
+D+++TWR +E G+V+ IG+SNF Q++RVL P A +Q+E H
Sbjct: 133 LFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVECHP 192
Query: 228 QNVQKEMVEFCQSEGVVVMGYSPFGS--LVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQ 285
Q E++EFC+ +G+ V YSP GS V + +T + ++DPV+ +IA+K G + Q
Sbjct: 193 FLAQNELIEFCKKQGITVTAYSPLGSPERVLQKRATTDPLLMEDPVVCAIAKKKGVSPAQ 252
Query: 286 IVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNH 345
+++R+Q++R V +PK+V P R+++N +F L+ +E + + + + R + +N
Sbjct: 253 VLIRYQLQRGVAVLPKSVMPSRIQQNFEALNFELSKEEFQALVNLNKNYRLLNFAPMKNM 312
Query: 346 PYYPFD 351
YYPF+
Sbjct: 313 KYYPFN 318
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 207 bits (505), Expect = 7e-52
Identities = 103/269 (38%), Positives = 164/269 (60%), Gaps = 13/269 (4%)
Query: 79 LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK-REDIFITTKLWNTQHRR 137
L + + AI VGYRHFD+ASVY TE+ IG AV +E+G++K R+++FIT+K WNT
Sbjct: 35 LASIFVDAIQVGYRHFDSASVYGTEEAIGMAVSKAIEQGLIKSRDEVFITSKPWNTDAHH 94
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD------YSHSDV---DFMETWRGLEDA 188
+ A+ +LKKLG++Y+DLYL+HWP+ L D +S D+ D TW+ +E+
Sbjct: 95 DLIVPALKTTLKKLGMEYVDLYLIHWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEEC 154
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
R+G+ K IG+ N+ ++L ++L+ TI P Q+E++ Q + EFC+ +G+ V +
Sbjct: 155 YRLGLAKSIGICNYGTKKLTKLLEIATIPPAVNQVEMNPSWQQGNLREFCKQKGIHVSAW 214
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SP G+ GS G +++ +L IA GKT Q+ LRW ++ + K+ N +R+
Sbjct: 215 SPLGAYKIFWGS---GAVMENQILQDIATAKGKTIAQVALRWVYQQGSSAMAKSFNKERM 271
Query: 309 EENINIFDFTLTPDEVEKINGFDTHTRYT 337
++N+ IFDF L+ +E+EKI +YT
Sbjct: 272 KQNLEIFDFELSEEELEKIKQIPQRRQYT 300
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 206 bits (502), Expect = 2e-51
Identities = 113/302 (37%), Positives = 179/302 (59%), Gaps = 21/302 (6%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G ++++K+L D + A++ GYRH DTA+ YE E+ IG+ +K + +KR DIFI TK
Sbjct: 20 GTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSKKLKRSDIFIVTK 79
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN--ADYSH-----------SDV 176
L +R +V + I SL+ L L+Y+DLYL+H PIG D H +
Sbjct: 80 LPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPFDENGHIRLDNST 139
Query: 177 DFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVE 236
+ +E W +E + G K IGLSNFN Q++R+LK +K +QIE+H+ QKE+V+
Sbjct: 140 NHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMKISMLQIELHVYFQQKELVK 199
Query: 237 FCQSEGVVVMGYSPFG--SLVARHGSTVE-GPKIDDPVLSSIAQKYGKTTPQIVLRWQIE 293
FC+ E + + YSP G SL+ T E + + V+ IA+KY K++ QI+LR+ ++
Sbjct: 200 FCKQENIPITAYSPLGSRSLIKLLNKTEEISDMLQNDVVMEIAKKYKKSSAQILLRYIVQ 259
Query: 294 RKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFD--THTRYTLPSFW---QNHPYY 348
+V IPK++NP+R++ENI +FD+ + P++++K+ D +R F+ + HP Y
Sbjct: 260 NGIVVIPKSINPQRIKENIQLFDWEINPEDMKKLYNLDRGESSRICDLKFFKGIETHPEY 319
Query: 349 PF 350
PF
Sbjct: 320 PF 321
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 205 bits (501), Expect = 2e-51
Identities = 112/311 (36%), Positives = 173/311 (55%), Gaps = 17/311 (5%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRA-IDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV 119
G Q LF G + KD+ V +RA +D GYR DTA +Y+ E IG+ + + G +
Sbjct: 11 GAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYISSGKL 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL------------ 167
KREDIF+T+KL T H +V + + LK L L+YIDLYL+H P
Sbjct: 71 KREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGSFAPLME 130
Query: 168 NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHL 227
N + + +++ ++TWR LE + G +K +G+SNF+ QL+ + +KP Q+E H+
Sbjct: 131 NGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVKPANQQVECHI 190
Query: 228 QNVQKEMVEFCQSEGVVVMGYSPFGS---LVAR-HGSTVEGPKIDDPVLSSIAQKYGKTT 283
Q+E+ C+ GV V Y+P GS AR G EG + +P++ +A KY KT
Sbjct: 191 YWPQQELRALCKKLGVTVTAYAPLGSPGRKAARPDGVWPEGDPLLEPIVKQLAAKYHKTA 250
Query: 284 PQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQ 343
QI++R + + IPK+V+P R+ ENI+ FDF L+ +++ +N +T TR + F
Sbjct: 251 AQILIRHLTQHGISTIPKSVSPDRIVENISTFDFKLSDEDMHTLNSIETRTRLFIADFAV 310
Query: 344 NHPYYPFDKVD 354
HP++P D +D
Sbjct: 311 KHPFFPHDDID 321
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 204 bits (499), Expect = 4e-51
Identities = 118/312 (37%), Positives = 177/312 (56%), Gaps = 22/312 (7%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G++ + G ++ D+++ + A++ GYRH DTA VY E+ IG +K ++ G VK
Sbjct: 12 GEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGKVK 71
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IGLNADYSHS---- 174
RE++FI TK+ +R EV I SL+ L LDY+DLYL+H P I +N D S
Sbjct: 72 REELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLDKE 131
Query: 175 ---DVDFMET----WRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHL 227
+VD W +E G+ K IG+SNF+K Q+ R+LK I+P QIE H+
Sbjct: 132 GLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKIRPANNQIEHHV 191
Query: 228 QNVQKEMVEFCQSEGVVVMGYSPFGS-----LVARHGSTVEGPKI-DDPVLSSIAQKYGK 281
Q+++V+FC+SE + V YSP GS A G + P + D P + IA +GK
Sbjct: 192 YLQQRDLVDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGK 251
Query: 282 TTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSF 341
T Q++LRW I+ V IPK+ NP RL++N+++FDF LT +EV K++ D + R +F
Sbjct: 252 TPAQVLLRWIIDTGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIRICDFAF 311
Query: 342 W---QNHPYYPF 350
+ + HP + F
Sbjct: 312 FHGVERHPEFTF 323
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 203 bits (495), Expect = 1e-50
Identities = 112/286 (39%), Positives = 167/286 (58%), Gaps = 16/286 (5%)
Query: 80 RDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTE 139
+ V+ A+ GYRH DTA++Y+ E +IG+A+ EG++KREDIFITTK + +
Sbjct: 32 KTVIRNAVLAGYRHIDTATLYQNEHQIGDALAELFAEGILKREDIFITTKAFCHEVAPDV 91
Query: 140 VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS-HSDVDFMETWRGLEDAQRMGIVKGIG 198
V +A+ +SLK+L LDY+DLYL H P D S SDV + WRG E +G+ K IG
Sbjct: 92 VEEALRNSLKRLRLDYVDLYLAHIPASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIG 151
Query: 199 LSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG-----S 253
+SNFN+ Q+ R++ + A Q+E+HL QK E C+ +++ Y+ G S
Sbjct: 152 VSNFNESQIVRIMNIQKVPIHASQLELHLYLPQKAHRELCKKHNILITAYATLGSPGRMS 211
Query: 254 LVARHG-----STVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKR 307
+V +G ST +++D + ++AQKY KT QI+LR +E ++ IPKT NP+R
Sbjct: 212 VVGSNGRPLFESTQNSENEMNDKHVKALAQKYSKTPAQILLRATVEMGIIVIPKTTNPER 271
Query: 308 LEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQN---HPYYPF 350
++ENINIFDF ++ EV + + T+ +W N HP PF
Sbjct: 272 MKENINIFDFNISNAEVNLLEAHE-RTKQERLFWWPNVADHPEDPF 316
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 201 bits (491), Expect = 4e-50
Identities = 99/251 (39%), Positives = 153/251 (60%), Gaps = 15/251 (5%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
A+ GYRH DTA++Y+ E+ +G ++ V RED+FITTKLWNT+ A
Sbjct: 40 ALCAGYRHIDTAAIYKNEESVGAGLRASG----VPREDVFITTKLWNTEQGYESTLAAFE 95
Query: 146 DSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQ 205
+S +KLG+DYIDLYL+HWP G + S ++++WR E + V+ IG+SNF+
Sbjct: 96 ESRQKLGVDYIDLYLIHWPRGKDI-LSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIH 154
Query: 206 QLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGP 265
LE VL T+ P Q+E+H N Q ++ FC ++ + V +SP G +G
Sbjct: 155 HLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLG----------QGK 204
Query: 266 KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVE 325
+ +P+LS+I KY KT Q++LRW I++ ++ IPK+V+ +R+EEN +IFDF L ++V
Sbjct: 205 LLSNPILSAIGAKYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVM 264
Query: 326 KINGFDTHTRY 336
I+ +T++RY
Sbjct: 265 SIDALNTNSRY 275
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 201 bits (490), Expect = 5e-50
Identities = 114/302 (37%), Positives = 170/302 (56%), Gaps = 25/302 (8%)
Query: 54 ELSFE-APGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKM 112
E SF+ + G + L G K++ + V A+D GYRH D A+VY E+E+GEA
Sbjct: 2 EPSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTK 61
Query: 113 K-VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY 171
K E VKRED+FIT+KLWNT H++ V A+ +L LGL Y+DLYL+HWP+ +Y
Sbjct: 62 KFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAF--EY 119
Query: 172 SHSDV-------DFM---ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI 221
+ +D+ +F+ ETW +E G+VK IGLSNFN Q L VL IKP A
Sbjct: 120 TSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAAN 179
Query: 222 QIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGK 281
Q+E+H Q E+ +FC + + YSP G+ G +D+ + +IA+KY K
Sbjct: 180 QVELHPFLSQPELKKFCDKHNIHLTAYSPLGN----------GAFVDNEEVGAIAKKYNK 229
Query: 282 TTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPS- 340
T P ++ +W I++ IPK+ P R+ EN ++F+F + ++ ++ D + R P+
Sbjct: 230 TIPNVLCKWAIQKNFSVIPKSSTPSRVAENFDLFNFEIEEADMLFLDKMDKNLRTCDPAK 289
Query: 341 FW 342
FW
Sbjct: 290 FW 291
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 199 bits (486), Expect = 1e-49
Identities = 103/256 (40%), Positives = 156/256 (60%), Gaps = 13/256 (5%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVA 141
++RAI++GYRHFDTA +Y TE +GEAV V G++ R D+F+T+K+W + V
Sbjct: 38 MLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVV 97
Query: 142 QAINDSLKKLGLDYIDLYLMHWPIGL---NADYSHS------DVDFMETWRGLEDAQRMG 192
A ++L+ LG+DY+DL L+HWP+ L N D+ D WRG+E+ R+G
Sbjct: 98 PAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGMEECHRLG 157
Query: 193 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
+ + IG+SNF+ ++LE++L ++P Q+EV+ Q+ + E C+ EGV + GYSP G
Sbjct: 158 LARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPLG 217
Query: 253 SLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENI 312
+ GS +D VL IA GKT QI LRW E+ V + KT N KR++EN+
Sbjct: 218 AKGTPWGSAA---VMDSGVLQEIAGAKGKTLAQICLRWLYEQGDVLLVKTYNEKRMKENL 274
Query: 313 NIFDFTLTPDEVEKIN 328
+IF++ LT +E E+I+
Sbjct: 275 DIFNWELTDEERERIS 290
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 199 bits (486), Expect = 1e-49
Identities = 96/260 (36%), Positives = 162/260 (62%), Gaps = 12/260 (4%)
Query: 77 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHR 136
K ++ ++ A+ GYRHFDTA+ Y +EQ +GEA+K + G+V R+D+F+T+KLW T++
Sbjct: 36 KDTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENH 95
Query: 137 RTEVAQAINDSLKKLGLDYIDLYLMHWPIG-----LNADYSHSDV---DFMETWRGLEDA 188
V A+ SLK L L+Y+DLYL+HWP+ + D+ D W +E+
Sbjct: 96 PHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEEC 155
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
Q++G+ K IG+SNF+ ++L+ +L TI+P Q+E++L QK++ EFC+ G++V +
Sbjct: 156 QKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAF 215
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SP +R + V +++ VL IA+ +GK+ Q+ LRW E+ V +PK+ + +R+
Sbjct: 216 SPLRKGASRGPNEV----MENDVLKEIAEAHGKSIAQVSLRWLYEQGVTFVPKSYDKERM 271
Query: 309 EENINIFDFTLTPDEVEKIN 328
+N++IFD+ LT + KI+
Sbjct: 272 NQNLHIFDWALTEQDHHKIS 291
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 199 bits (485), Expect = 2e-49
Identities = 103/312 (33%), Positives = 171/312 (54%), Gaps = 25/312 (8%)
Query: 55 LSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 114
+SFE G + + G KS ++ + V A++ GYRH D A +Y+ E E+G A+
Sbjct: 4 ISFEN-GDEMPMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSF 62
Query: 115 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYS 172
+ G ++R+D+++T+KLWN H +V A+ +L L LD +DLYL+HWP+ L D+
Sbjct: 63 DAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQPEVDFP 122
Query: 173 HSDVDFM--------ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIE 224
S DF+ ETW +E ++ G+V+ IG+SNF+ L+ +L G ++P+ Q+E
Sbjct: 123 ESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVE 182
Query: 225 VHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDD-------PVLSSIAQ 277
+H Q E+V F ++ + + YSP GS G + K DD P ++ IA
Sbjct: 183 MHPYLPQPELVSFAEAHNIPITAYSPLGS-----GDRPDAMKADDEPTLMANPTINDIAD 237
Query: 278 KYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYT 337
++G + Q++L+W + R IPK+ P +++N+ D L+ DE+E I+ D+ RY
Sbjct: 238 RHGVSPAQVLLQWGVARGTAVIPKSTTPAHIKDNLAAADLDLSADELETIDSLDSKYRYL 297
Query: 338 LPSFW--QNHPY 347
+ W + PY
Sbjct: 298 AGAAWTMEGSPY 309
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 198 bits (482), Expect = 5e-49
Identities = 97/259 (37%), Positives = 163/259 (62%), Gaps = 12/259 (4%)
Query: 79 LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK-REDIFITTKLWNTQHRR 137
+R V A+ +GYRHFDTA++Y +EQ +G+A+ + EG++K R+++FIT+KLW + R
Sbjct: 35 VRKAVTEALKLGYRHFDTAALYNSEQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHR 94
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGL---NADYSHSDVDFME-----TWRGLEDAQ 189
V A+ +LK L L+YID+YL+HWP+ N +Y DF++ W +E+ Q
Sbjct: 95 ENVEPALQKTLKNLKLEYIDMYLIHWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQ 154
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
++G+ K IG+SNF+ ++L VL + P Q+EV+ QK++ EFC+S G++V+ Y+
Sbjct: 155 KLGLTKAIGVSNFSCKKLSDVLANAKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYA 214
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
G++ +G+ + VL+ IA+ G T Q+ LRW E+ + + K+ N +R+E
Sbjct: 215 ALGAVGTFYGT---NRVMGSEVLNEIARIRGNTVAQVCLRWAYEQGIGVLVKSFNKERME 271
Query: 310 ENINIFDFTLTPDEVEKIN 328
+N+ IF++TL+ DE +KI+
Sbjct: 272 QNLQIFNWTLSDDESKKIS 290
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 197 bits (481), Expect = 6e-49
Identities = 104/284 (36%), Positives = 165/284 (58%), Gaps = 26/284 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G SK+ + + + AID GYRH DTA Y+ E+E+GEA++ K+EEGVV RED+F+TTK
Sbjct: 22 GTWLSKEGEGVEAIKAAIDAGYRHIDTAYFYQNEKEVGEAIRAKIEEGVVCREDLFVTTK 81
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
+D+ LM P + SDVD+++TW+ +E
Sbjct: 82 F----------------------IDWDTKNLM--PYDADGKLQFSDVDYIDTWKAMEKLL 117
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+ G VK IG+SNFN +Q+ R+L E IKP Q+E + Q+++ EFC++ + + YS
Sbjct: 118 KTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQVECNPSLNQRKLTEFCKNLDITLTAYS 177
Query: 250 PFG--SLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKR 307
P G + + + P +DDP + I +KY KT+ Q++LR+ ++ +PIPK+ N +R
Sbjct: 178 PLGRPNYYEKDPDNMPKPALDDPKVIEIGKKYNKTSGQVILRYLVDIGTIPIPKSSNSER 237
Query: 308 LEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFD 351
+ +NI+IFDF LT +E++ ++GF T R + +H Y+PF+
Sbjct: 238 IRQNIDIFDFKLTEEEIKIMDGFHTGQRTVPFNLCTSHKYFPFN 281
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 196 bits (477), Expect = 2e-48
Identities = 109/276 (39%), Positives = 162/276 (58%), Gaps = 14/276 (5%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVA 141
++RAI++GYRHFDTA +Y TE + EAV V G+V R D+F+T+KLW + V
Sbjct: 40 LLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVASRADVFVTSKLWCSDLHAGRVV 99
Query: 142 QAINDSLKKLGLDYIDLYLMHWPIGL---NADYSHSDVDF-----ME-TWRGLEDAQRMG 192
A ++L+ LG+DY+DL L+HWP + + D+ + ME WRG+E+ R+G
Sbjct: 100 PAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGMEECHRLG 159
Query: 193 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
+ + IG+SNF+ ++LE++L ++P A Q+E++ Q+ + E C+ EGV + GYSP G
Sbjct: 160 LARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQLCGYSPLG 219
Query: 253 SLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENI 312
+ GS +D VL IAQ GKT QI LRW E+ V + KT N R++EN+
Sbjct: 220 AKGTPWGSAA---VMDSGVLHDIAQTKGKTLAQICLRWMYEQGDVLLVKTYNENRMKENL 276
Query: 313 NIFDFTLTPDEVEKINGFDTHTRYTLPSF-WQNHPY 347
+IFD+ LT +E +KI+ T F N PY
Sbjct: 277 DIFDWELTEEERDKISKLPQQRGLTGMQFVCDNGPY 312
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 195 bits (476), Expect = 2e-48
Identities = 111/282 (39%), Positives = 160/282 (56%), Gaps = 22/282 (7%)
Query: 50 LSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEA 109
+ +T+LS G F ++ SKD + + A+D GYRH D A +Y E +GEA
Sbjct: 1 METTQLSNGVTIPMLG-FGTYLIDSKD--VPAAIKTALDAGYRHLDCAHIYGNEPAVGEA 57
Query: 110 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 169
+K + R D+FIT+K+WN + A + +L L LDY+DLYL+HWP N
Sbjct: 58 IKASG----IDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP---NE 110
Query: 170 DYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQN 229
D +D TWR LE + V+ IG+SNF++ QL++V + T+KP QIE H
Sbjct: 111 DDFELTLD---TWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIERHPYK 167
Query: 230 VQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLR 289
VQ ++ +F +V GYSP G HG + ++DPV++ +A+KYGK+ QIVLR
Sbjct: 168 VQADLGQFDTDNDIVNEGYSPIG-----HGHLI----LEDPVITKLAEKYGKSPAQIVLR 218
Query: 290 WQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFD 331
WQI+ V PK+ P R++EN I F+LT DE+ +ING D
Sbjct: 219 WQIDTGFVVFPKSSKPARVKENFEISGFSLTADEIAEINGLD 260
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 195 bits (475), Expect = 3e-48
Identities = 101/259 (38%), Positives = 156/259 (60%), Gaps = 14/259 (5%)
Query: 80 RDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV-KREDIFITTKLWNTQHRRT 138
R + A++VG+RHFDTA++Y TE +GEA+ G+V RE++F+TTKLW TQ
Sbjct: 36 RGAALAALEVGFRHFDTAALYGTEAPLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPG 95
Query: 139 EVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD-----YSHSDV---DFMETWRGLEDAQR 190
V ++ +SL+ L ++Y+DLYL+HWPI + D DF WR +E+ R
Sbjct: 96 LVLPSLRESLRNLQMEYVDLYLVHWPISVKPGPPMLPVKREDAVPFDFEGVWRAMEECHR 155
Query: 191 MGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 250
+G+ K IG+SNF + L+++L TI P Q+E++ Q+ + E+C ++G+ V YSP
Sbjct: 156 LGLAKAIGVSNFTTKHLDKLLAVATIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSP 215
Query: 251 FGSLVARHGSTVEGPKI-DDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
G EG + + PVL+ IA+ GK+ Q+ LRW E+ V PIPK+ N +RL+
Sbjct: 216 LGG----QNWIGEGNDVMESPVLADIARARGKSIAQVSLRWIHEQGVTPIPKSYNKERLK 271
Query: 310 ENINIFDFTLTPDEVEKIN 328
+N+ IFD+ LT ++ KI+
Sbjct: 272 QNLEIFDWELTKEDRLKIS 290
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 194 bits (472), Expect = 7e-48
Identities = 104/277 (37%), Positives = 164/277 (59%), Gaps = 12/277 (4%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGV-VKREDIFITTKLWNTQHRRTEVA 141
+ A++ GYR DTA VY EQ +G+A++ +G + RED+FI +KL T HR V
Sbjct: 29 IKSAVEFGYRLIDTAFVYNNEQVVGQALREIFSQGNDINREDVFIVSKLGPTFHRPEAVE 88
Query: 142 QAINDSLKKLGLDYIDLYLMHWPI-----GLNADYSHSD--VDFMETWRGLEDAQRMGIV 194
+ SL++LGLDY+DLYLMH P+ G D S D V +ETW+ LE+ QR G+V
Sbjct: 89 KGCRLSLERLGLDYVDLYLMHTPVAARDSGDGNDRSEIDDEVTPLETWKALEECQRKGLV 148
Query: 195 KGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSL 254
+ IG+SNFN++QL ++ G+I+P Q+E + Q ++ +FC EG+++M YSP G
Sbjct: 149 RSIGVSNFNEEQLMEIVTHGSIRPVVNQVECSIGFHQVKLRKFCNREGILIMAYSPLGK- 207
Query: 255 VARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINI 314
+ G + +D L+ +A+KYG++ QI LR+ IE +PIPK+ R++EN+++
Sbjct: 208 -PKPGK--KHVFLDSSDLNKMAEKYGRSPAQISLRFLIEIGTIPIPKSSKTDRMKENLDV 264
Query: 315 FDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFD 351
F L +V+ + F R + ++ +YPF+
Sbjct: 265 LSFKLEETDVQALESFVKQQRSMTLDWLKSSKHYPFN 301
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 193 bits (471), Expect = 1e-47
Identities = 98/276 (35%), Positives = 162/276 (58%), Gaps = 6/276 (2%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G S + ++ V AI GYRH D A Y E+E+G+ +K + +G VKRE++F+TTK
Sbjct: 19 GTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAIAKGYVKREELFVTTK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN---ADYSHSDVDFMETWRGLE 186
LW+T + +V A +SLKKL L+Y+DLY++H P+ + +++ + ETWR +E
Sbjct: 79 LWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTADKKTGEFTEEIIPIEETWREME 138
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 246
G+VK IG+SNFN ++LE +L I+P Q E H+ + ++ +FC+ + +
Sbjct: 139 KLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHIYYQRPKLHQFCKKHNIHIT 198
Query: 247 GYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
GY P G+ G V P ++ V+ +IA+K+ K QI +++ I IPK+V+ +
Sbjct: 199 GYCPLGNPGISSG--VPAP-FENEVVKAIAKKHNKKAAQICIKFSIASGHSVIPKSVHEE 255
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW 342
R++EN +FDF L +++EK+ G D + + SF+
Sbjct: 256 RIKENGEVFDFELDEEDMEKLRGLDKNIKVCDMSFY 291
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 193 bits (471), Expect = 1e-47
Identities = 98/250 (39%), Positives = 154/250 (61%), Gaps = 14/250 (5%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
D V A+ +GYRH D A +Y E+EIG +K E+ VVKRED+FIT+KLW T H +V
Sbjct: 33 DAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDV 92
Query: 141 AQAINDSLKKLGLDYIDLYLMHWP-------IGLNADYSHSDVDFMETWRGLEDAQRMGI 193
+A+N +LK L L+Y+DLYL+HWP +G+ + + VD TW+ +E G
Sbjct: 93 PEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE-NLLPVDIPSTWKAMEALYDSGK 151
Query: 194 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 253
+ IG+SNF+ ++L +L+ + P Q+E H Q ++ EFC+S+GV + YSP GS
Sbjct: 152 ARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGS 211
Query: 254 LVARHGST-VEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENI 312
G+T ++ + +P+L+ +A+K GK+ Q+ LRW ++ +PK+ N R++EN
Sbjct: 212 ----PGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENF 267
Query: 313 NIFDFTLTPD 322
N+FD+++ PD
Sbjct: 268 NVFDWSI-PD 276
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 192 bits (469), Expect = 2e-47
Identities = 103/296 (34%), Positives = 169/296 (57%), Gaps = 15/296 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G ++ D+++ + A++ GYRH DTA VY E+ IG+ +K ++ G V R+++FI TK
Sbjct: 21 GTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMDAGKVTRDELFIVTK 80
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---NADYSHSD--------VDF 178
L R + V + + +SL L L+Y+DLY +H P + + + D D
Sbjct: 81 LPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFLVEDGLIVLETTTDH 140
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFC 238
+ W+ +E+ G+ + IGLSNFN++Q++R+L IKP +QIE H+ Q E+V+FC
Sbjct: 141 VALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIENHIYLQQPELVKFC 200
Query: 239 QSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERKVV 297
++ G+ V YSP GS E P +D+PV+ IA+K GK+ Q++LR ++R +
Sbjct: 201 KANGITVTAYSPLGSKGIEKLLGREVPDLLDNPVVKDIAEKLGKSPAQVLLRHLLQRGIS 260
Query: 298 PIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW---QNHPYYPF 350
IPK+ NP RL +NI++F F + ++ ++N D + R F+ HP +PF
Sbjct: 261 TIPKSTNPTRLRDNIDLFGFEIDDSDMVRLNQLDQNIRICDFGFFPGITKHPEFPF 316
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 192 bits (467), Expect = 3e-47
Identities = 108/293 (36%), Positives = 158/293 (53%), Gaps = 22/293 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G+ K V AI VGYRH D+A+ Y EQ++GE + + EG+ RE+++ITTK
Sbjct: 23 GLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIARAIAEGLCSREELWITTK 82
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA-------------DYSHSD- 175
LWNT HR V A S+ LGLDYIDLYL+H+PI L D+S D
Sbjct: 83 LWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRYVDFNDRYPAEWIFDHSAEDP 142
Query: 176 ------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQN 229
V ETW +E G+V+ IG+ N++ L ++ IKP +QIE H
Sbjct: 143 AMELDQVPLSETWGAMEQLVESGLVRQIGVCNYSAVLLHDLMSYARIKPAMLQIESHPYL 202
Query: 230 VQKEMVEFCQSEGVVVMGYSPFGSL--VARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIV 287
Q+ ++ +S + V +SP GSL V + + + DP + + AQ+ G T Q+V
Sbjct: 203 TQEALLRTARSYNMAVTAFSPLGSLSYVELNMAGANDTVLTDPSVLAAAQRNGVTAAQVV 262
Query: 288 LRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPS 340
LRW I+R IPKT NP+RL EN+ + +FTL +E++ I+ + + R+ P+
Sbjct: 263 LRWGIQRGTAVIPKTSNPQRLIENLTLTEFTLNDEEMDAISALNQNHRFNDPA 315
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 191 bits (466), Expect = 4e-47
Identities = 119/343 (34%), Positives = 176/343 (51%), Gaps = 53/343 (15%)
Query: 25 SLKMNNGRDMPAIGLGTYLGFDQAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDVVM 84
+ K+N+G +P+IGLGTY E PG+ + D +
Sbjct: 16 NFKLNDGNQIPSIGLGTYYS-------------ENPGE----------------VGDAIN 46
Query: 85 RAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAI 144
A+ GYRH D A+ Y E+ IG ++K +EG +KREDIF T+KLWN+ H V +
Sbjct: 47 NALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHC 106
Query: 145 NDSLKKLGLDYIDLYLMHWPI--------GL--------NADYSHSDVDFMETWRGLEDA 188
+++ LG+ Y+DLYL+HWPI GL N + + V ETW+ +E
Sbjct: 107 VKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKL 166
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
+G+VK IG+SNFN Q L +L IKP Q+E+H Q ++ E+C + ++ Y
Sbjct: 167 VELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAY 226
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SP G S + +L SIA KY K+ ++ +W +R + IPK+ N R+
Sbjct: 227 SPLGQGKCDFFS--------NKILKSIAGKYKKSVANVIFKWLNQRGIAAIPKSGNHSRI 278
Query: 309 EENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFD 351
EN NIFDF L+ D++EKIN + + R P + P+Y FD
Sbjct: 279 IENFNIFDFQLSNDDIEKINSLNANIRTCSPITFFGTPFYLFD 321
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 191 bits (465), Expect = 5e-47
Identities = 114/297 (38%), Positives = 166/297 (55%), Gaps = 26/297 (8%)
Query: 79 LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRT 138
L V+ A++ G H DT+ VY+ E+ IG+ +K +G KREDIF+T+KL +
Sbjct: 54 LETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWFAKGG-KREDIFVTSKLPYYDNHPE 112
Query: 139 EVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYS---HSDVDFMETWRG 184
V + I SL+KLGL Y+D+YL+H P + N D S + D + W+
Sbjct: 113 SVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSYELATNEDGSVVLDTQTDPIAVWKE 172
Query: 185 LEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVV 244
+E + G K IGLSNFN+ Q+ +LKE IKP +Q+EVH + QK ++EFCQ G++
Sbjct: 173 MEKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSNLQVEVHAYHQQKPLIEFCQKNGII 232
Query: 245 VMGYSPFGSLVAR---HGSTVEGPKIDD---PVLSSIAQKYGKTTPQIVLRWQIERKVVP 298
V GY+P GS AR H +E D PV++ IA+K+GK+ QI+L +++ +
Sbjct: 233 VTGYAPLGSPGARKELHPGQMEEEFPDVFKLPVVNEIAKKHGKSVVQILLHHLVQKGIAV 292
Query: 299 IPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR-----YTLPSFWQNHPYYPF 350
I + NP L+ENI IFDF LT DE++ ++ D R Y + H YYPF
Sbjct: 293 IFSSKNPNHLKENIEIFDFELTEDEMKSLDALDKGERGKIFDYKFLKGIEKHQYYPF 349
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 190 bits (464), Expect = 7e-47
Identities = 102/266 (38%), Positives = 153/266 (57%), Gaps = 20/266 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV K D+Q+ +VV A+D GYR FDTA Y E+ +G A+K V+R+++FIT+K
Sbjct: 20 GVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSALK----HSNVERDELFITSK 75
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
LWN + + N SL LGLDY+DL+L+HWP +D ++E+++ LE
Sbjct: 76 LWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPC-------ENDQLYIESYKALEHLY 128
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G +K IG+ NF LE+++KE I P QIE+H Q+++ +FC + V +
Sbjct: 129 EEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPYFNQQDVQDFCDEHDIKVTAWM 188
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P L+ G +DDPV++ IA +Y KT QIVLRW + + IPK+ PKR++
Sbjct: 189 P---LMRNKGL------LDDPVITDIAHRYDKTPAQIVLRWHLAHNRIIIPKSQTPKRIK 239
Query: 310 ENINIFDFTLTPDEVEKINGFDTHTR 335
EN +IFDF L +V +I+ + + R
Sbjct: 240 ENFDIFDFNLELTDVAEIDSLNKNAR 265
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 190 bits (463), Expect = 9e-47
Identities = 96/267 (35%), Positives = 157/267 (58%), Gaps = 24/267 (8%)
Query: 70 GVVKSKD-KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
GV K+K K+ ++ V+ A++ GYRH DTA +Y+ E ++G+A++ E + R++IFITT
Sbjct: 26 GVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQAIR----ESGIPRKEIFITT 81
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDA 188
KLWN + +A+ +SL +LG+D++DLYL+H+P+ M++W+ LE
Sbjct: 82 KLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSKR---------MDSWKELEKL 132
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
+ K IG+SN+ L +LK I P Q+E H Q ++E+C+ + + Y
Sbjct: 133 YHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEFHPFLNQIHLLEYCKKHKIQLEAY 192
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SP G KI+DP ++ IAQKY KT QI++RW IE+K+V IPK++ +R+
Sbjct: 193 SPLA----------HGQKIEDPTIAKIAQKYDKTPAQILIRWAIEQKIVVIPKSIKKERI 242
Query: 309 EENINIFDFTLTPDEVEKINGFDTHTR 335
EN +FDF ++ ++++ +N D R
Sbjct: 243 IENSKVFDFAISEEDMKILNSLDEDFR 269
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 190 bits (463), Expect = 9e-47
Identities = 97/289 (33%), Positives = 165/289 (57%), Gaps = 18/289 (6%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V A++ GYRH D+A ++ ++E+ +K + V+RE++F+++K+WNT H R Q
Sbjct: 34 VRDALEAGYRHIDSALSFKNQEEVAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQ 93
Query: 143 AINDSLKKLGLDYIDLYLMHWPIG----------------LNADYSHSDVDFMETWRGLE 186
I++ L+ Y+DL ++HWP G N +SDVD++ETW+ LE
Sbjct: 94 QIDEMLEIFETTYMDLIVIHWPFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALE 153
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 246
DA R G ++ IGL+NFN Q+E+V +G IKP +Q+E++ Q+E+ +FC+ +G+++
Sbjct: 154 DAHRSGKIRSIGLANFNIGQVEQVWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILT 213
Query: 247 GYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNP 305
+ G+ + E P + + L SIA+ +GK+ Q+++RW I+ + + K+
Sbjct: 214 AFMLTGNPGSALYRKHEDPNLLYNETLQSIAKGHGKSVVQVLVRWAIDLRTTALVKSSES 273
Query: 306 KRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQ-NHPYYPFDKV 353
KR+ +NINIF F LT E+ +I + R P +HPY+P+ V
Sbjct: 274 KRIRQNINIFKFRLTSQEIARIKALNIDFRILNPLLGNYDHPYFPWPHV 322
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 190 bits (463), Expect = 9e-47
Identities = 112/303 (36%), Positives = 166/303 (54%), Gaps = 20/303 (6%)
Query: 66 LFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIF 125
L +NG K ++ + V+ A++ GYRHFD+A+ Y E IG+ ++ + EG VKRE++F
Sbjct: 32 LGRNG--KMSEEAVTAVLETALECGYRHFDSAAYYGNEAIIGQVLRRWISEGKVKREELF 89
Query: 126 ITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG--------LNADYSHSD-- 175
ITTKL +R +VA+ + SL L L Y+DLYL+H+P G L+AD D
Sbjct: 90 ITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHYPCGILDTDRERLSADEVTVDPT 149
Query: 176 VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMV 235
D WR +E G K IGLSNFN Q++R++K ++P +Q+EVH+ Q +
Sbjct: 150 TDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIKGCQVRPAVLQVEVHVYMQQGALR 209
Query: 236 EFCQSEGVVVMGYSPFGS--LVARHGSTVEGPK--IDDPVLSSIAQKYGKTTPQIVLRWQ 291
FC +VV + P G + R S K ++DP + +A + KT Q++LR+
Sbjct: 210 AFCAQHDIVVCAFCPLGGPFRLIRKASRPGEVKLLLEDPQVLDVATAHHKTPAQVLLRYL 269
Query: 292 IERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDT-HTRYTLPSFWQ---NHPY 347
+ V+PIPK+ NP RL +N IFDF LT E+ ++ G D H F + HP
Sbjct: 270 HQINVIPIPKSANPTRLFQNTQIFDFELTSAEMSRLAGLDRGHEGRIFTEFRRGDHTHPE 329
Query: 348 YPF 350
+PF
Sbjct: 330 FPF 332
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 190 bits (463), Expect = 9e-47
Identities = 93/253 (36%), Positives = 155/253 (61%), Gaps = 16/253 (6%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V A+ +GY H DTASVY EQ+I + + +KRED+FIT+K+ + + +
Sbjct: 43 VTEALKIGYTHIDTASVYRNEQDIAKVIHNPAYG--IKREDLFITSKISPGEQGYEQAKK 100
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNA----DYSHSDVDFMETWRGLEDAQRMGIVKGIG 198
A+ D L +L + Y+D L+HWP G++ D ++ + +ETW+ L + ++ G++K IG
Sbjct: 101 AVQDMLTRLNIKYLDCVLIHWP-GVSKLPPNDPKNAQIR-LETWKALIELRKAGVIKHIG 158
Query: 199 LSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARH 258
+SNFN L+ ++++ KP+ Q E+H K+ +EFCQ G++V YSP L +H
Sbjct: 159 VSNFNINHLQHLIEKSEFKPEMNQFEIHPLCFNKKTIEFCQKNGILVEAYSP---LARQH 215
Query: 259 GSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFT 318
++ P+++ +AQKY KT Q++LRW ++ +V IPK+ P+R++ENI+I DF
Sbjct: 216 EKVMK-----HPLINQLAQKYKKTVAQVILRWALQNNMVIIPKSKTPQRIQENIDILDFA 270
Query: 319 LTPDEVEKINGFD 331
L+P E+E++N D
Sbjct: 271 LSPQELEQMNQLD 283
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 190 bits (462), Expect = 1e-46
Identities = 102/281 (36%), Positives = 163/281 (58%), Gaps = 24/281 (8%)
Query: 70 GVVK-SKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
GV K +K + V AI +GYRHFDTA +Y E+++G A+ E+ + RE+ FIT+
Sbjct: 22 GVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAI----EKSQIPREEFFITS 77
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDA 188
K+WNT H +A + KKL ++Y+D+YL+H+ + Y ++ETW +E+
Sbjct: 78 KVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFA----SSY------YLETWHAMEEL 127
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
G +K IG++NF Q LE ++K I P QIE H + Q E+ ++ ++ +
Sbjct: 128 YLQGKIKVIGVANFQIQHLEELMKHSRITPMINQIETHPEFPQNELHQYLTKHKILHEAW 187
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
+P G G+ +++ VL IA + KT Q++LRW I+R ++ IPK+ NPKR+
Sbjct: 188 APLGQ-----GNKA---LLENTVLKKIASNHEKTVAQVILRWHIQRGIIIIPKSSNPKRI 239
Query: 309 EENINIFDFTLTPDEVEKINGFDTHTRYT-LPSFWQNHPYY 348
+ENI +FDF L+ +E+EKIN +T RY+ P+ + +P Y
Sbjct: 240 KENIQLFDFELSSEEMEKINQLNTGKRYSHSPTGYMINPLY 280
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 189 bits (461), Expect = 2e-46
Identities = 93/280 (33%), Positives = 158/280 (56%), Gaps = 13/280 (4%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS + ++ V A++ GY+H D A+ Y+ E +GEA K E G VKREDIF+T+K
Sbjct: 18 GTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKESFESGNVKREDIFVTSK 77
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD---YSHSDVDFM------- 179
LWN H++ +V A+ +LK L LDY+DLYLMHWP+ + D D++
Sbjct: 78 LWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPSVNGFPEKDEDYLSLEEAPL 137
Query: 180 -ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFC 238
ET + +A++ G++K +G+SNF+K++LE + + P+ Q+E+H Q ++ +C
Sbjct: 138 HETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMNQVELHPYLPQNDLYSYC 197
Query: 239 QSEGVVVMGYSPFGSLVARHGSTVEG-PKI-DDPVLSSIAQKYGKTTPQIVLRWQIERKV 296
EG+++ GYSP GS G + P + +D + +A++ + Q ++ W +R
Sbjct: 198 SKEGILLTGYSPLGSGDRSEGMKADDEPSLFEDDTIKKVAERNNISKGQTLIAWAKQRGT 257
Query: 297 VPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRY 336
IPK+ N R++EN+ + L+ +++E I + R+
Sbjct: 258 AVIPKSTNEGRIKENLESDNIELSKEDLEDIANIGKNYRF 297
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 189 bits (461), Expect = 2e-46
Identities = 103/285 (36%), Positives = 160/285 (56%), Gaps = 14/285 (4%)
Query: 52 STELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK 111
ST L +A G + G K++ ++RD V A+ GY H D A+ Y E E+GEA++
Sbjct: 4 STILVNDANGLRIPRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALR 63
Query: 112 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD- 170
E G KRED+F+T+KLWN + R +V +A+ +L LG+ Y+DLYL+HWP+
Sbjct: 64 EAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKRGT 123
Query: 171 --YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE--GTIKPDAIQIEVH 226
++ E W LE G+V+ IG+SNFN+ QL + + I+P QIE H
Sbjct: 124 VLQPDAEASIAECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIESH 183
Query: 227 LQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQI 286
+V++ QS+G+ V YSP +A+ G E + +L +A+KYG T Q+
Sbjct: 184 PLWSNDSLVKYSQSKGLTVTAYSP----LAQGGELFE-----NEILVGLAKKYGVTPAQV 234
Query: 287 VLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFD 331
VLRW ++R VV IPK+ + KR+ N ++F F L+ ++++ + D
Sbjct: 235 VLRWNVQRDVVVIPKSTSAKRIASNADLFGFELSDEDMDAMKVLD 279
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 189 bits (461), Expect = 2e-46
Identities = 110/298 (36%), Positives = 169/298 (56%), Gaps = 37/298 (12%)
Query: 52 STELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK 111
ST++ G Q G +SK+ V+ A+ GYRH DTA++Y E ++G+A+K
Sbjct: 8 STKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK 67
Query: 112 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY 171
+ V RE+IF+TTKLW TQH EVA ++ SLK+LGLDY+DLYLMHWP L+ Y
Sbjct: 68 ----DSGVPREEIFVTTKLWCTQHHEPEVA--LDQSLKRLGLDYVDLYLMHWPARLDPAY 121
Query: 172 -SHSDV------------------DFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL- 211
+ D+ +F++TW +++ + G K +G+SNF+ L+ +L
Sbjct: 122 IKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLA 181
Query: 212 KEGT-IKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDP 270
+G + P A Q+E+H Q E++ FC+S+G+VV YSP GS + P + +P
Sbjct: 182 SQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGS--------TDAPLLKEP 233
Query: 271 VLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKIN 328
V+ IA+K +V+ W ++R V +PK+VNP R++ N I FTL+ ++ E IN
Sbjct: 234 VILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKI--FTLSTEDFEAIN 289
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 188 bits (459), Expect = 3e-46
Identities = 102/298 (34%), Positives = 164/298 (55%), Gaps = 16/298 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G +S +++ + V AI++GYRH D A +Y E EIGEA+ + EG VKRE++F+T+K
Sbjct: 22 GTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVLTEGKVKREELFVTSK 81
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI----GLNADYS-------HSDVDF 178
LW H +V A +LK L LDY+DLYL+H P+ G+ +S ++
Sbjct: 82 LWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLPHSIAEGIIGYTPEGV 141
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFC 238
TW+ +E G+ K IG+SNF+ ++L ++L+ +I P Q+E+H Q+++ EFC
Sbjct: 142 QNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIVPACNQVELHPYLPQEKLKEFC 201
Query: 239 QSEGVVVMGYSPFGS---LVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
S+G+++ YSP G+ LV + E +++PV+ IA K+ + +++LRW I+R
Sbjct: 202 DSKGILLTAYSPLGNPGRLVPKERLEREPKVMEEPVIKEIAAKHNCSVARVLLRWGIQRG 261
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYY--PFD 351
+PK+ + L +N + LT DE+ I T RY + Y PFD
Sbjct: 262 YPVLPKSTSRDHLHDNFSALGLVLTDDEMAAIKSITTRQRYLTQGWMYAEGEYVDPFD 319
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 188 bits (458), Expect = 4e-46
Identities = 104/273 (38%), Positives = 157/273 (57%), Gaps = 22/273 (8%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G + + GV + ++ + V AI VGYR DTA+ Y E+ +G A+K ++EG+V+
Sbjct: 11 GVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKRAIDEGIVR 70
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 180
RE++F+TTKLW + +A SLKKL L+YIDLYL+H P G D
Sbjct: 71 REELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG----------DVHC 120
Query: 181 TWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQS 240
W+ +E+ + G+V+ IG+SNF +L ++ I P QIE+H ++E +EF ++
Sbjct: 121 AWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIEIHPFYQRQEEIEFMRN 180
Query: 241 EGVVVMGYSPFGSLVARHGSTVEGPK--IDDPVLSSIAQKYGKTTPQIVLRWQIERKVVP 298
+ + PF EG K + VL SIA+KYGKT Q++LRW ++ +V
Sbjct: 181 YNIQPEAWGPF----------AEGRKNIFQNGVLRSIAEKYGKTVAQVILRWLTQKGIVA 230
Query: 299 IPKTVNPKRLEENINIFDFTLTPDEVEKINGFD 331
IPKTV +R++ENI+IFDF LT +++EKI D
Sbjct: 231 IPKTVRRERMKENISIFDFELTQEDMEKIATLD 263
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 188 bits (458), Expect = 4e-46
Identities = 97/262 (37%), Positives = 165/262 (62%), Gaps = 20/262 (7%)
Query: 70 GVVKSKDKQ-LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
G K+ +++ ++ + A+ +GYR DT ++Y+ E+ +G+A+K + GV+ RE+IF+TT
Sbjct: 17 GTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR---GVL-REEIFVTT 72
Query: 129 KLW--NTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLE 186
KLW N +++T +A +++SL+KL L+YIDLYL+HWP +Y +TWR +E
Sbjct: 73 KLWRENLGYKQTRIA--LDESLRKLDLNYIDLYLIHWPANA-INYKDWQKTNADTWRAME 129
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 246
+ Q G +K +G+SNF + LE + + + P QIE H Q ++ EFC++ G+ V
Sbjct: 130 ELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFHPGYWQPQVTEFCKNHGIAVE 189
Query: 247 GYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
+SP +AR G + +L +++KY K+ Q+ LRW I+ V+ IPK+ +P+
Sbjct: 190 SWSP----LAR------GKVFGNDLLIGLSKKYQKSVSQVCLRWIIQHDVIAIPKSSSPE 239
Query: 307 RLEENINIFDFTLTPDEVEKIN 328
R++ENI++FDF L+ +E++KIN
Sbjct: 240 RIKENIDVFDFELSKEEMKKIN 261
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 188 bits (458), Expect = 4e-46
Identities = 100/268 (37%), Positives = 155/268 (57%), Gaps = 17/268 (6%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
D V+ A+ GYRH DTA+VY TE+ IG A+ + R+++FIT+KLWN +HR +V
Sbjct: 32 DAVLTALSAGYRHIDTAAVYGTEKAIGRALA----RSRLSRDELFITSKLWNNKHRPEDV 87
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQ 189
QAI+ SLK L +DY+DLYLMHWP + D+D+++T++ +E
Sbjct: 88 EQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLV 147
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+ G K IG+SNF+K ++ER+L+ +I P +Q+E+H Q + VE+ +S+G+ V YS
Sbjct: 148 KSGKTKAIGISNFSKGEMERLLESCSIVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYS 207
Query: 250 PFGSL-VARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
G+ G G I+DP L++I KYGKT Q+ L W I + + K+ P R+
Sbjct: 208 SLGNQNEVYSGRERYGRLIEDPALAAIGTKYGKTGAQVALAWGITKGHSVLVKSKTPHRI 267
Query: 309 EENINIFDFTLTPDEVEKINGFDTHTRY 336
++N DF L ++++ I D R+
Sbjct: 268 QQNFE-SDFELKQEDMKAIENIDKKLRF 294
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 188 bits (457), Expect = 5e-46
Identities = 108/292 (36%), Positives = 159/292 (54%), Gaps = 25/292 (8%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V A++ GYRH DTA Y E+ IG+ +K ++G KRED+FITTKL R V
Sbjct: 55 VTAALESGYRHIDTAFTYGNEEAIGKTLKKWFDKGG-KREDLFITTKLPPIGMRAEYVES 113
Query: 143 AINDSLKKLGLDYIDLYLMHWPIG-----------LNADYS---HSDVDFMETWRGLEDA 188
+ SL+KLGL+Y+++YL+H P LN D S +D D + WR +E
Sbjct: 114 YLKLSLEKLGLEYVNMYLIHKPFAFVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQ 173
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
+ G V+ IGLSNFNK QL V + IKP +QIE+ N Q+ M E C + V +
Sbjct: 174 VKAGRVRSIGLSNFNKSQLLNVYEHAEIKPSNLQIELQAYNQQRPMRELCAERNITVTAF 233
Query: 249 SPFGSLVARHGSTVEGPK-----IDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTV 303
S GS + K D P++ IA+ + +T+ Q++LR ++ ++ +PK+
Sbjct: 234 STLGSPGSSPDKKTRYIKSLPTLFDHPIVKKIAEAHNRTSAQVLLRHAVQNGIIVLPKST 293
Query: 304 NPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW-----QNHPYYPF 350
NP R+++NI IFDF LT DE++ +NG D + + F+ + HP YPF
Sbjct: 294 NPGRIKQNIGIFDFALTEDEMQAMNGLDKGEKGRIFHFFIDKGVEKHPQYPF 345
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 188 bits (457), Expect = 5e-46
Identities = 92/259 (35%), Positives = 149/259 (57%), Gaps = 12/259 (4%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G ++ V AI+ GYRH DTA+VY E+ +G+ +K + +KRED+F+T+K
Sbjct: 25 GTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGIK----DSGIKREDLFVTSK 80
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
LWNT + +A ++L +L +DY+DLYL+HWP + ETWR +ED
Sbjct: 81 LWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFGDDAAKINAETWRAMEDLY 140
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G ++ IG+SNF + ++K + P QIEVH E+V++ Q+ ++V ++
Sbjct: 141 NEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVHPGWPHTEVVKYLQAHNILVEAWA 200
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P G G+ V + +P + IA KY KT Q+ LRW +++ ++P+PK+V+ +R+
Sbjct: 201 PLGG----QGAKV----LTNPTMIQIADKYQKTPAQVCLRWVLQQGILPLPKSVHKERMI 252
Query: 310 ENINIFDFTLTPDEVEKIN 328
N NIFDF LT +++ KI+
Sbjct: 253 SNQNIFDFELTDEDMRKIS 271
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 188 bits (457), Expect = 5e-46
Identities = 89/252 (35%), Positives = 144/252 (57%), Gaps = 15/252 (5%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+ + AID GY+H D A++Y+ E+ +G +K E + R+D+F+T+K+WN Q
Sbjct: 31 NAIKTAIDAGYKHIDAAAIYKNEKGVGLGIK----EANIDRKDLFVTSKVWNEQRGYENT 86
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLS 200
+A ++++ L LDY+DLYL+HWP + + ++ +TW +E + G +K +G+S
Sbjct: 87 LKAFDNTINDLQLDYLDLYLIHWPAAAHQFENWKQLN-NDTWSAMEKLYKDGKIKALGVS 145
Query: 201 NFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGS 260
NF + L +L+ TIKP QIE H +Q++ V+FC + V G+SP G
Sbjct: 146 NFMEHHLTPLLQHATIKPTVNQIEYHPGYMQQDCVQFCNDNNIQVEGWSPLG-------- 197
Query: 261 TVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLT 320
G D+ VL +A KY KT Q+ +RW I+ V+P+PK+V P R+ EN + DF ++
Sbjct: 198 --RGDVFDNEVLKQLAHKYNKTVAQLSIRWAIQNNVIPLPKSVTPNRIIENFEVSDFNIS 255
Query: 321 PDEVEKINGFDT 332
++ IN DT
Sbjct: 256 ESDMALINKIDT 267
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 186 bits (454), Expect = 1e-45
Identities = 106/279 (37%), Positives = 159/279 (56%), Gaps = 18/279 (6%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G K ++ + + A++ GYRH DTA Y+ E IG+ +K ++G KREDIFIT+K
Sbjct: 40 GTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKILKKWFDKGG-KREDIFITSK 98
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS------------DVD 177
L + +R V + SLK LGLDY+D+YL+H P + + S DVD
Sbjct: 99 LPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDLFDDVD 158
Query: 178 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 237
W+ +E + G K IGLSNFN+ Q+ + IKP +Q+E H QK++ +F
Sbjct: 159 HKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQLRKF 218
Query: 238 CQSEGVVVMGYSPFGSLVAR----HGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQI 292
C+ +V+ Y+P GS AR G+ E P ++ P++ S+A KY K+ QI+LR I
Sbjct: 219 CKEHNIVMTAYAPLGSHNARLNLHRGTPKELPALVELPLIKSLAAKYNKSPGQILLRHTI 278
Query: 293 ERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFD 331
+ +V IPK+ N +R + NI+IFDF LT +E++KI+ D
Sbjct: 279 QEGLVAIPKSSNAQRQKSNIDIFDFKLTDEEMKKIDALD 317
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 186 bits (454), Expect = 1e-45
Identities = 96/264 (36%), Positives = 155/264 (58%), Gaps = 20/264 (7%)
Query: 70 GVVKSKDKQLR-DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
G ++ D Q+ D V+ A+ GYRH DTA+ Y E+ +G+A+ + GV RED+F+TT
Sbjct: 25 GTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAI---ADSGVA-REDLFVTT 80
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW--PIGLNADYSHSDVDFMETWRGLE 186
KLWN H +A++ SL KLGLDY+DLYL+HW P + ++ + D TWR +E
Sbjct: 81 KLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPAAMRDNWEQLNAD---TWRAME 137
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 246
+A + IG+SNF + L+ +LK + P QI ++ +++ E+V + + ++
Sbjct: 138 EAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQIFLNPSDMEDEVVAYNRKHDILSE 197
Query: 247 GYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YSP G+ G P L ++A KY K+ Q+VLRW ++ +P+PK+V+
Sbjct: 198 AYSPLGT----------GKIFSIPELKTLADKYDKSVAQVVLRWSLQHGFLPLPKSVHAD 247
Query: 307 RLEENINIFDFTLTPDEVEKINGF 330
R+E+N +FDF L+ D+++ I+GF
Sbjct: 248 RIEQNTELFDFELSDDDMKVIDGF 271
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 186 bits (454), Expect = 1e-45
Identities = 99/276 (35%), Positives = 161/276 (58%), Gaps = 24/276 (8%)
Query: 61 GQQCGLFQNGVVKSKD-KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV 119
G + F GV K ++ + + V AI GYR DTA++Y+ E+ +G +K E GV
Sbjct: 14 GVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIK---ESGVA 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFM 179
RE++FIT+K+WN A SL++L LDY+DLYL+HWP +
Sbjct: 71 -REELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP---------GKDKYK 120
Query: 180 ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQ 239
+TWR LE + G ++ IG+SNF LE +LK+ IKP Q+E H + QKE+ ++C+
Sbjct: 121 DTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCK 180
Query: 240 SEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPI 299
++G+ + +SP ++G +D+ VL+ IA+K+ K+ Q++LRW ++ +VV I
Sbjct: 181 AQGIQLEAWSPL----------MQGQLLDNEVLTQIAEKHNKSVAQVILRWDLQHEVVTI 230
Query: 300 PKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR 335
PK++ R+ EN +IFDF L+ ++++KI+ + R
Sbjct: 231 PKSIKEHRIIENADIFDFELSQEDMDKIDALNKDER 266
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 186 bits (453), Expect = 1e-45
Identities = 98/265 (36%), Positives = 151/265 (56%), Gaps = 25/265 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G +SK ++RD V+ A+ GYRH D A+VY EQE+G+ +++ V RE+IF+T+K
Sbjct: 21 GTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGMRLSG----VPREEIFLTSK 76
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH-------------SDV 176
LWNT H V +A++ SL L DY+DLYL+HWP+ + DV
Sbjct: 77 LWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQPVNEQTGLIDVVDV 136
Query: 177 DFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVE 236
+TW +E G V+ IG+SNF ++++E +LK I P QIE H Q++++E
Sbjct: 137 PIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITPAVNQIEAHPFLQQRDLLE 196
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKV 296
+ +G+VV GYSP G+ + V DDP++ A+K KT Q+++ W ++R
Sbjct: 197 WSTQKGIVVAGYSPLGNNIYNIPRAV-----DDPLVIETAKKLNKTPAQVLISWAVQRGT 251
Query: 297 VPIPKTVNPKRLEENINIFDFTLTP 321
V +PK+V P+R+E N F +L+P
Sbjct: 252 VVLPKSVTPERIESN---FQGSLSP 273
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 186 bits (452), Expect = 2e-45
Identities = 101/269 (37%), Positives = 153/269 (56%), Gaps = 21/269 (7%)
Query: 67 FQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFI 126
F G + + VV AI++GYRH DTAS+Y E+E+G A+ G+ KRE+ F+
Sbjct: 23 FGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGRAI---ASSGI-KREEFFV 78
Query: 127 TTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLE 186
TTKLWN+ + +A SL L LDY+DLYL+HWP + Y + W L
Sbjct: 79 TTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWPCPPSELY-------INVWEVLL 129
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 246
+ + G K +G+SNF + ++++ + G P QIE+H Q+E+V C+++G+ +
Sbjct: 130 ELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQIELHPWLQQRELVLSCRNDGIQIE 189
Query: 247 GYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
+ PF AR ++ P L+ A++YGKT Q++LRW I++ V PKTV+ +
Sbjct: 190 SWGPF----ARFSKDLDA----FPELTRPAKQYGKTPAQVILRWHIQKGYVVFPKTVHAE 241
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTR 335
RL +NI+IFDF LTPDE+ I+ D R
Sbjct: 242 RLRQNIDIFDFDLTPDEISGIDSLDAGFR 270
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 185 bits (450), Expect = 3e-45
Identities = 101/278 (36%), Positives = 161/278 (57%), Gaps = 26/278 (9%)
Query: 58 EAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG 117
+ P G+FQ V ++D ++ + A+ GYRH DTA+ Y EQ +GEA++ E
Sbjct: 21 QIPQLGLGVFQ--VDNAEDT--KNAIKWALAAGYRHIDTAAYYGNEQWVGEAIR----ES 72
Query: 118 VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVD 177
V R+ IF+T+KLWN+ E A ++L KLGLDY+DLYL+HWP
Sbjct: 73 DVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPAP----------G 122
Query: 178 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 237
++++WR +ED + G +K IG+SNFN+ Q+ +L GT+KP QIE H Q +M +
Sbjct: 123 YLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQIETHPYFQQNDMHAY 182
Query: 238 CQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVV 297
+S+G++ +SP G G+ + D V++ +A + + QI+LRW ++R+ V
Sbjct: 183 LESQGILHEAWSPLGG-----GN---NNALTDSVINELAAAHDVSAAQIILRWHVQREEV 234
Query: 298 PIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR 335
IPK+++ R+++N +IF F L DE++ I+ DT R
Sbjct: 235 VIPKSIHEARIQQNRDIFAFGLDEDEMKAISDLDTGKR 272
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 183 bits (445), Expect = 1e-44
Identities = 103/290 (35%), Positives = 151/290 (52%), Gaps = 20/290 (6%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G+ K ++ D + AI GYR FD A Y E E G+ V ++EG+VKRED+FI +K
Sbjct: 20 GLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVARAIQEGIVKREDLFIVSK 79
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----------------NADYSH 173
LWN+ H V L GLDY DL+++H+PI L N
Sbjct: 80 LWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVDPAVRYPPGWLSENNKLEF 139
Query: 174 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKE 233
S+ ETW +E + + IG+SNF+ Q L +L+ I+P +QIE H Q+
Sbjct: 140 SNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYARIRPATLQIEHHPYLTQER 199
Query: 234 MVEFCQSEGVVVMGYSPFGSLVARH---GSTVEGPKI-DDPVLSSIAQKYGKTTPQIVLR 289
+V + Q EG+ V YS FG L E PK+ D V+ IAQK+GKT Q++LR
Sbjct: 200 LVTYAQKEGIAVTAYSSFGPLSFVELDLKDAHETPKLFDHDVIKGIAQKHGKTPAQVLLR 259
Query: 290 WQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
W +R + IPK+ +P RL +N+++ + L E+E I+ + + R+ P
Sbjct: 260 WATQRNIAVIPKSNDPTRLAQNLDVTGWDLETSEIEVISSLNRNLRFNDP 309
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 182 bits (443), Expect = 2e-44
Identities = 101/283 (35%), Positives = 156/283 (55%), Gaps = 20/283 (7%)
Query: 80 RDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQHRRT 138
++ + AIDVGYR FDTA Y E +GEA++ K+ E + R+D FI +KL + HR+
Sbjct: 33 KEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRDDFFIISKLSGSYHRQD 92
Query: 139 EVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS-----------HSDVDFMETWRGLED 187
V + +L +LG+DY+DLYLMH P+ L ++ + E W GLE
Sbjct: 93 LVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNAIDDSIAPTEAWIGLEQ 152
Query: 188 AQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
+ G+ + IG+SNFN+ Q+ +L + +I P QIE + Q+ M +FCQ + ++VMG
Sbjct: 153 CYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQRPMRKFCQQQNILVMG 212
Query: 248 YSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKR 307
Y+P G + P + + L IA KTT Q+ LR+ I+ VVPI K+ + KR
Sbjct: 213 YTPLGK--------QKLPFLQNNRLKEIALSVDKTTAQVSLRYLIDEGVVPIVKSTDRKR 264
Query: 308 LEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+EN++IFDF LT ++E+++ R F ++PF
Sbjct: 265 QQENLDIFDFKLTKQQLEELDAIGGDQRACKMDFLAGAKHFPF 307
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 181 bits (441), Expect = 4e-44
Identities = 100/272 (36%), Positives = 151/272 (55%), Gaps = 19/272 (6%)
Query: 61 GQQCGLFQNGVVKS-KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV 119
GQ+ GV K+ D + A D GYRH D+A+ Y E+ +G A+ +E V
Sbjct: 24 GQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWTKENNV 83
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFM 179
R +IFIT+KLW+ H + A AI DSLKKL +DY+D+YLMH P + A+ +
Sbjct: 84 PRSEIFITSKLWDADHDKA--AAAIEDSLKKLNVDYMDMYLMHSPGTMGAEKR------L 135
Query: 180 ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQ 239
E W+ LE+A G +K IG+SNF+ ++L+ +L IKP QIE H +E+ E C
Sbjct: 136 EAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIKPAVNQIESHPFFAHEELREACI 195
Query: 240 SEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPI 299
S G+ + YSP +G +D P + +IA K+GKT QI+L+W + + +
Sbjct: 196 SRGIHIQAYSPM----------AQGQALDRPEIKTIASKHGKTPAQILLKWGLTHGNIIL 245
Query: 300 PKTVNPKRLEENINIFDFTLTPDEVEKINGFD 331
PK++ R+E N +FDF L D+++ ++ D
Sbjct: 246 PKSLTKHRIESNAQLFDFELDSDDMDVLDNLD 277
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 180 bits (439), Expect = 7e-44
Identities = 97/266 (36%), Positives = 155/266 (58%), Gaps = 24/266 (9%)
Query: 66 LFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIF 125
+F G + Q + V+ A + GYR DTA Y+ EQ++GEAVK + R+++F
Sbjct: 14 IFGFGTYEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVKASG----LNRDEVF 69
Query: 126 ITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
ITTK + T++ +++SL+++GLDY DL L+HWP+G D+D TW L
Sbjct: 70 ITTKTMTDGYEDTKIG--LDESLRRIGLDYFDLVLIHWPMG-------HDID---TWHAL 117
Query: 186 EDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVV 245
E A + G + IG+SNFN +Q ++ + +++P QIE HL Q +M EF + E +V
Sbjct: 118 EAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVH 177
Query: 246 MGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNP 305
YSP G+ + I +PVL I++KYGK+ Q++LR+ ++ VV IP++ NP
Sbjct: 178 ESYSPLGN--------GQQNLISNPVLKEISEKYGKSPIQVILRYLVQNDVVTIPRSTNP 229
Query: 306 KRLEENINIFDFTLTPDEVEKINGFD 331
++ NI+IFDF L D+++++ D
Sbjct: 230 AHIKSNIDIFDFELDNDDLKRLRVLD 255
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 180 bits (438), Expect = 1e-43
Identities = 98/249 (39%), Positives = 149/249 (59%), Gaps = 25/249 (10%)
Query: 73 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK--- 129
KS ++++ V AID GYRH D A VY+ E E+GEA++ K++E VKRED+FI +K
Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101
Query: 130 ---LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLE 186
LW T R V +A +LK L L Y+D+YL+HWP G A +E
Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKA---------------ME 146
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEGVV 244
+ G+VK +G+SNFN Q+E++L + +K P Q+E H Q++++++C S+G+
Sbjct: 147 ELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGIT 206
Query: 245 VMGYSPFGSLVARHGSTVEGPKI-DDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTV 303
+ YSP GS R + E P + ++P + IA K+ KTT Q+++R+ I+R V+ IPK+V
Sbjct: 207 ITAYSPLGS-PDRPWAKPEDPSLLEEPKIKEIAAKHKKTTAQVLIRFHIQRNVIVIPKSV 265
Query: 304 NPKRLEENI 312
P R+ ENI
Sbjct: 266 TPARIVENI 274
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 180 bits (438), Expect = 1e-43
Identities = 113/333 (33%), Positives = 179/333 (53%), Gaps = 48/333 (14%)
Query: 28 MNNGRDMPAIGLGTYLGFDQAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAI 87
+NNG+ MPAIGLGT+L APG+ + V A+
Sbjct: 8 LNNGKFMPAIGLGTWLA--------------APGE----------------VGKAVTLAL 37
Query: 88 DVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK--REDIFITTKLWNTQHRRTEVAQAIN 145
+ GYR D A Y+ E+EIGE M +E + RE++F+T+KLW Q T + ++
Sbjct: 38 ENGYRLIDCARFYKNEKEIGE---MGIEPFLKNHPREELFVTSKLWMDQV--TRIRESCL 92
Query: 146 DSLKKLGLDYIDLYLMHWPIGLNADYSHS-------DVDFMETWRGLEDAQRMGIVKGIG 198
+S++ L Y+DLYL+HWPI L D S+ D+D E W+ +E G+VK IG
Sbjct: 93 ESIQDLKCKYLDLYLIHWPIALKVDASNPPKPEDFLDMDITEIWQEMERLVDEGLVKSIG 152
Query: 199 LSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARH 258
LSNF Q+E+++K IKP Q+E+++ Q ++ E C+S +VV Y P G A
Sbjct: 153 LSNFTIPQIEKIMKMCRIKPVINQVELNVYLQQNKLREVCKSYNIVVEAYRPIGGKPANE 212
Query: 259 GSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFT 318
+ +DD V+ S+A+KY KTT QI LRW ++ ++ +PK+ NP RL +N +F+++
Sbjct: 213 S---DKNCLDDEVVVSLAKKYNKTTAQICLRWLVQNGIIAVPKSTNPNRLLQNYQVFEWS 269
Query: 319 LTPDEVEKINGFDTHTR-YTLPSFWQNHPYYPF 350
L+ ++++ + + + R ++W Y F
Sbjct: 270 LSNEDMKALEKRNLNKRNVKFENYWNGKTYEEF 302
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 180 bits (438), Expect = 1e-43
Identities = 85/246 (34%), Positives = 152/246 (61%), Gaps = 15/246 (6%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V+ A++ GYRH DTAS Y E +G A+ ++ + R ++FITTKLWN+ H + +
Sbjct: 38 VLAALNCGYRHIDTASAYGNEDSVGRAI----QKSGINRHELFITTKLWNSDHGYEKTKK 93
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
AI+ SL L LDY+D+YL+HWP + ++++ E+WR +E+A R G ++ IG+SNF
Sbjct: 94 AIDQSLLDLKLDYLDMYLIHWPNPSSMRDHWAEIN-AESWRAMEEAVRAGKIRAIGVSNF 152
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
K L+ +++ IKP QI ++ ++Q E+V + ++ YSP G+
Sbjct: 153 RKHHLDALMETAEIKPVVNQIFLNPSDLQSEVVTENKKLDLLSEAYSPLGT--------- 203
Query: 263 EGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPD 322
G + + V+ +A YGK+T Q+++RW ++ +P+PK+V+P+ ++ N ++FDF ++P+
Sbjct: 204 -GGLLGNEVVKEVAANYGKSTAQVLIRWSLQHGFLPLPKSVHPEYIKANADVFDFEISPE 262
Query: 323 EVEKIN 328
++ K++
Sbjct: 263 DMAKLD 268
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 179 bits (436), Expect = 2e-43
Identities = 91/262 (34%), Positives = 154/262 (58%), Gaps = 21/262 (8%)
Query: 74 SKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNT 133
S D+Q+ + + A+D+GYR DTA++Y E+ +G A+ +E + REDIF+TTKLWN
Sbjct: 25 SDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNAL----QETDIPREDIFVTTKLWND 80
Query: 134 QHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGI 193
+H + A+ +SL+KL LDY+DLYL+HWP Y + W+ L + Q+ G+
Sbjct: 81 RH--LDARAALTESLEKLQLDYVDLYLIHWPAPPQDQY-------VGAWQQLIELQKEGL 131
Query: 194 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 253
++ IG+SNF + ++R++ E + P QIE+H Q+++ + + +V +SP
Sbjct: 132 IRSIGVSNFQPEHIQRLINETGVHPVINQIELHPLLQQRQLHAWNATHNIVTESWSP--- 188
Query: 254 LVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENIN 313
+A+ G V D+ ++ + QKYGKT Q+V+RW I+ ++ IPK+ R++EN +
Sbjct: 189 -LAQGGENV----FDNQLVQHLTQKYGKTPAQVVIRWHIDNGMIVIPKSTTLSRIKENFD 243
Query: 314 IFDFTLTPDEVEKINGFDTHTR 335
+FDF L +++ + D R
Sbjct: 244 VFDFKLEKEDLTAMTTLDIGKR 265
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 179 bits (436), Expect = 2e-43
Identities = 94/284 (33%), Positives = 158/284 (55%), Gaps = 22/284 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G ++K ++ + V A+ GYRH D A++Y E E+G ++ + V RE+IFIT K
Sbjct: 21 GTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR----KSGVPREEIFITGK 76
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG---------LNAD--YSHSDVDF 178
LWNT+H +V A++ +L+ LG+ Y+DLYLMHWP LN D + +++D+
Sbjct: 77 LWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGDKWFPLNDDGVFDLANIDY 136
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFC 238
+ T+R +E G V+ IG+SNFN ++LE +L + ++ P QIE H Q ++++FC
Sbjct: 137 ITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQIEAHPYLQQPDLLQFC 196
Query: 239 QSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVP 298
QS+G+++ YSP G + T E +DDP++ +A + ++ W ++R V
Sbjct: 197 QSKGILIEAYSPLG-----NNQTGEPRTVDDPLVHRVAGELSLDPGPLLASWGVQRGTVV 251
Query: 299 IPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW 342
+ K+V P R+ N+ + L ++N + H R+ P W
Sbjct: 252 LSKSVTPARIAANLRV--RALPEGAFAQLNSLERHKRFNFPGHW 293
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 179 bits (435), Expect = 2e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 23/259 (8%)
Query: 70 GVVKSKDKQLRDVVMRAID-VGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
GV K++ + + +++AID GYR DTA VY E+ +G A+K + +KREDIFITT
Sbjct: 18 GVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNAIK----QTKIKREDIFITT 73
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDA 188
K+W + + +I+ SLKKL +YIDL L+H P G D+ W+ LE
Sbjct: 74 KVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG----------DYYSAWKALEVL 123
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
+ GIVK IG+SNF +L +KP QIE+H + E + + GV V +
Sbjct: 124 YKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHPLRQRIEDLHWNNKYGVAVESW 183
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
+ FG R S + +++P+L S+A+KY KT PQI+LRW I++ +V IPKTV RL
Sbjct: 184 ASFG----RATSEI----MENPILVSLAEKYNKTVPQIILRWLIQQNIVVIPKTVTESRL 235
Query: 309 EENINIFDFTLTPDEVEKI 327
+EN++IFDF ++ D+++ I
Sbjct: 236 KENMDIFDFEISDDDMDLI 254
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 179 bits (435), Expect = 2e-43
Identities = 94/286 (32%), Positives = 159/286 (55%), Gaps = 25/286 (8%)
Query: 50 LSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEA 109
LSST + G + F G+ +K + V+ A++ GYR DTA+ Y E+ +GEA
Sbjct: 3 LSSTRTLSD--GYKIPRFGLGLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGEA 60
Query: 110 VKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA 169
++ E V R ++++ TK+++T H + +A + SL LG+DY+DLYL+H+P+
Sbjct: 61 LR----ESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPVPAGV 116
Query: 170 DYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQN 229
+ +W + + Q G+ + IG+SNFN LE + K I P QIEVH
Sbjct: 117 ---------VGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVHPYL 167
Query: 230 VQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLR 289
+E+V+FC+ + + YSP G K+ DP+L S+ KYGKT Q++LR
Sbjct: 168 QMEELVDFCRKHSIAIQAYSPL----------TRGEKLHDPLLRSLGDKYGKTPAQVLLR 217
Query: 290 WQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR 335
W +++ + I K+V R+ EN+++F+FT++ ++E ++G + + R
Sbjct: 218 WSLQKGYICISKSVQLSRIIENVDVFNFTISMADMEILDGLEENLR 263
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 179 bits (435), Expect = 2e-43
Identities = 102/272 (37%), Positives = 155/272 (56%), Gaps = 20/272 (7%)
Query: 79 LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRT 138
L + A+ +GYRH DTA +Y E+ IG +K +EGVV+R+D+FIT+KLWNT H
Sbjct: 30 LEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDEGVVQRKDLFITSKLWNTFHGCP 89
Query: 139 EVAQAINDSLKKLGLDYIDLYLMHWPIGLNA-----------DYSHSDVDFMETWRGLED 187
E + SL L +DY+DLYL+HWP+ + Y+ D + W+ +E
Sbjct: 90 E--DGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVESCGKKYNVGKFDAVGVWKKMEA 147
Query: 188 AQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
+G+ K IG+SNF K E++L I P AIQIE+H QKE+VEF +S+G+ V+
Sbjct: 148 LVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVIS 207
Query: 248 YSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKR 307
YS GS GS+ + DD + +IA+KYG QI+L + + + IPK+ + +
Sbjct: 208 YSSLGS---APGSSAK--VRDDKTIKAIAKKYGCAPSQIILSYITAQGICVIPKSRSKEH 262
Query: 308 LEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
L ENI++ + L+ +++ I+ +T RY P
Sbjct: 263 LRENIDLKE--LSREDISAIDALNTGHRYVDP 292
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 178 bits (433), Expect = 4e-43
Identities = 97/247 (39%), Positives = 146/247 (59%), Gaps = 15/247 (6%)
Query: 82 VVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVA 141
V+ AI GYRHFDTAS Y TE +G+AV E + RED F+T+KLW T+
Sbjct: 33 VLSNAIAQGYRHFDTASFYGTETALGQAVA----ESDIPREDFFLTSKLWKTEMGYDAAL 88
Query: 142 QAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSN 201
+A + +L++LG DY+DLYL+HWP + +D ETWR LE G+V+ IG+SN
Sbjct: 89 RAFDATLERLGTDYLDLYLIHWPRPDLELEDWAKLD-RETWRALERLYESGLVRAIGVSN 147
Query: 202 FNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGST 261
F LE +L + P Q+E H Q E V FCQ+ ++V +SP G R+ T
Sbjct: 148 FLPHHLEPILASANVAPMVDQLEFHPGYTQDEAVAFCQNHSILVEAWSPLG----RNRLT 203
Query: 262 VEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTP 321
G VL+ +A ++G + QI LR+ ++R V+P+PK+ +P+R+ EN+++F F+LT
Sbjct: 204 GNG------VLTRLAAEHGVSPAQICLRFALQRGVLPLPKSSSPERMAENLDLFSFSLTG 257
Query: 322 DEVEKIN 328
+E+ ++
Sbjct: 258 EEMAALS 264
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 177 bits (432), Expect = 5e-43
Identities = 100/279 (35%), Positives = 167/279 (59%), Gaps = 18/279 (6%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+IF T KLW T R
Sbjct: 36 QAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRA 95
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGI 197
V A+ SLKKLG DY+DL+++H P + + + +DA I++ +
Sbjct: 96 ELVHPALERSLKKLGPDYVDLFIIHVPFAMK----QPGKELLP-----KDASGEIILETV 146
Query: 198 GLSNFNKQQLERVLKEGTI--KPDAIQI-EVHLQNVQKEMVEFCQSEGVVVMGYSPFGSL 254
L + +LE +L + + KP Q+ E H Q +++EFC+S+ +V++ YS GS
Sbjct: 147 ELCD--TWELELILNKPGLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQ 204
Query: 255 VARHGSTVEGPKI-DDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENIN 313
+ P + ++P+L SIA+K+ ++ Q+ LR+Q++R VV + K+ + +R++EN
Sbjct: 205 RDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQ 264
Query: 314 IFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFDK 352
IFDF LTP++++ I+G + + RY + NHPY+PF +
Sbjct: 265 IFDFELTPEDMKAIDGLNRNLRYDNAA---NHPYFPFSE 300
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 177 bits (431), Expect = 7e-43
Identities = 102/286 (35%), Positives = 155/286 (54%), Gaps = 27/286 (9%)
Query: 59 APGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGV 118
A G Q G K +Q V AI GYRH D A Y E +AV +++
Sbjct: 15 ANGAQIPKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKKAG 70
Query: 119 VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG-LNADYS----- 172
V R +++T+KLWN+ H V +A++ SLK LG DY+DLYLMHWP+ LN+ S
Sbjct: 71 VPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVPSI 130
Query: 173 ---------HSDV--DFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI 221
D+ DFM T+R +E+ + G V+ IG+SNFN ++ V+ E +IKP
Sbjct: 131 RSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPVVN 190
Query: 222 QIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGK 281
Q+EV+L +E+ + + GV + YSPFGS + ++DPV+ +AQ+
Sbjct: 191 QVEVNLGVHNEELRNYAHAHGVTLQAYSPFGS------NQNVAKSLEDPVVVDVAQRNNI 244
Query: 282 TTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKI 327
T Q++L W + R ++PI K+V P+R+EEN + D L +E++ +
Sbjct: 245 TPAQVLLAWTLGRDIIPISKSVTPERIEENFRVLDIQLAEEEIKHL 290
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 176 bits (428), Expect = 2e-42
Identities = 102/263 (38%), Positives = 152/263 (57%), Gaps = 23/263 (8%)
Query: 70 GVVKSKD-KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
GV + D Q + VV ++VGYR DTA +Y EQ +G+A+K V REDIFIT+
Sbjct: 19 GVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAIK----HSNVPREDIFITS 74
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDA 188
K+W + +A +DS+KKL LDYIDLYL+H P D+ TWR LE
Sbjct: 75 KIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPYN----------DYYGTWRALERL 124
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
+ G ++ IG+S+F ++L ++ +KP QIE ++ N + + ++ + EGV +
Sbjct: 125 YQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQQYMEKEGVQPEAW 184
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
+PF A H T +P+L IA+K+ KTT Q++LRW ++R V IPK+V+ KRL
Sbjct: 185 APFAE-GANHIFT-------NPLLEEIAEKHHKTTAQVMLRWFLQRNYVVIPKSVHKKRL 236
Query: 309 EENINIFDFTLTPDEVEKINGFD 331
EN ++FDF L D+++KI D
Sbjct: 237 AENYDVFDFELDADDMKKIKTLD 259
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 175 bits (426), Expect = 3e-42
Identities = 89/260 (34%), Positives = 147/260 (56%), Gaps = 16/260 (6%)
Query: 70 GVVKSKD-KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
G K +D KQ + V A++VGYRH D A +YE + + + +K+ V R++IFIT+
Sbjct: 28 GTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLSVSQGIKLSG----VNRKEIFITS 83
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDA 188
K+WN +A + LK L L+Y+DL L+HWPIG + +V+ +TW+ +E+
Sbjct: 84 KIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKGFKDNWQEVN-AQTWKAMEEF 142
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
G +K IGLSNF +E + K I P Q+E H +Q E+VE+CQ +VV +
Sbjct: 143 YLEGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAW 202
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SPF + +++ L +A+KY T Q++L W I++ +VP+PK+ P+R+
Sbjct: 203 SPFS----------QSKVLENKTLVQLAKKYEVTVAQLILNWIIQKDIVPLPKSKTPERI 252
Query: 309 EENINIFDFTLTPDEVEKIN 328
N ++F+F + +++ I+
Sbjct: 253 RSNFDVFNFGINQADLKVID 272
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 175 bits (426), Expect = 3e-42
Identities = 99/277 (35%), Positives = 154/277 (55%), Gaps = 19/277 (6%)
Query: 59 APGQQCGLFQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG 117
A G + L GV + ++K + V+ AI GYR DTA+ Y E+E+GEA+ + +G
Sbjct: 7 ASGIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAINQG 66
Query: 118 VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVD 177
+VKRE++F+T+K+W + AI SL++L LDY+DLYL+H P D
Sbjct: 67 IVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYN----------D 116
Query: 178 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 237
WR +E A R G +K IG+SNF+ QL + + IKP QIEV+ K+ + +
Sbjct: 117 VFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQNKKDITY 176
Query: 238 CQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVV 297
GV V ++PF + + + +L IA K+ K+ QIVLRW +R ++
Sbjct: 177 FSQYGVQVEAWAPF--------AEGKNDLFSNILLRKIADKHHKSIAQIVLRWLTQRNII 228
Query: 298 PIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHT 334
+ K+V P+R+ +N++IFDF LT E+ +I DT++
Sbjct: 229 VVAKSVKPERMAQNLDIFDFKLTHQELAEIETLDTNS 265
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 175 bits (426), Expect = 3e-42
Identities = 102/300 (34%), Positives = 162/300 (54%), Gaps = 29/300 (9%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G + F G + +++ V+ AI GYR D A VY E+E+G+ ++ + G+VK
Sbjct: 11 GAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISSGIVK 70
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS------HS 174
RED+F+ +K W T R E+ ++ SLK LGLDY+DLYL+HWPI +N + + H+
Sbjct: 71 REDLFVVSKCWATYTTRCELG--LDQSLKLLGLDYVDLYLVHWPILMNPEGNDEKFPKHA 128
Query: 175 DV--------DFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVH 226
D + ++TW+ +E G K +G+SN++K LE++L T P Q+E H
Sbjct: 129 DGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVPAVNQVENH 188
Query: 227 LQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQI 286
Q Q+E+V+FC+ +G+ +M YSP GS GP + + IA+K+ + +
Sbjct: 189 PQLPQQELVDFCKEKGIHIMAYSPLGS--------TGGPLLTAEPVVKIAEKHSISPAAV 240
Query: 287 VLRWQIERKVVPIPKTVNPKRLEEN-----INIFDFTLTPDEVEKINGFDTHTRYTLPSF 341
+L +QI R + IPK+VNP R++ N ++ D L D E++ RY P F
Sbjct: 241 LLGYQIARGITVIPKSVNPDRIKANAQLKDLDAEDMKLLNDYSEQLAKDGKLNRYVFPPF 300
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 175 bits (425), Expect = 4e-42
Identities = 90/266 (33%), Positives = 147/266 (55%), Gaps = 22/266 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G ++KD + A++ GYRH DTA Y+ E+ +G+ + E V R DIF+TTK
Sbjct: 22 GTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQGIS----ECGVPRSDIFVTTK 77
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
LWN H A S + LG++Y+DLYL+HWP G N Y +ETWR E
Sbjct: 78 LWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP-GPNRSY-------IETWRAFEKLY 129
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
M V+ IG+SNF L+ +L T+ P Q+E+H QK + +C + + V +
Sbjct: 130 EMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEMHPHFQQKALRAYCAEKNIAVTAWR 189
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P G +G + +P L +A+K+ ++ Q+++RW I+ V+ IPK+ + +R++
Sbjct: 190 PLG----------KGALLTEPQLVELAEKHKRSAAQVIIRWLIQLGVIAIPKSSHEERIK 239
Query: 310 ENINIFDFTLTPDEVEKINGFDTHTR 335
+N ++FDF L+P+++ +I D ++R
Sbjct: 240 QNFDVFDFELSPEDMRRIESMDRNSR 265
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 175 bits (425), Expect = 4e-42
Identities = 93/253 (36%), Positives = 158/253 (62%), Gaps = 21/253 (8%)
Query: 84 MRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQA 143
+ A+ GY+H DTA+ Y E ++G A+ + GV R++IF+TTKLWN QH+ E A
Sbjct: 41 LTALKNGYKHIDTAAAYGNEDQVGRAI---ADSGV-SRDEIFVTTKLWNDQHKDPE--GA 94
Query: 144 INDSLKKLGLDYIDLYLMHWPIGLN--ADYSHSDVDFMETWRGLEDAQRMG-IVKGIGLS 200
+++SLKKLGL+Y+DLYL+HWP+ ++ + + D DF++TWR L+ + G VK IG+S
Sbjct: 95 LDESLKKLGLEYVDLYLIHWPLSVDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVS 154
Query: 201 NFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARH 258
NFNK++L+++L EG + P QIE H Q ++ ++ +S+ + + YSP G A
Sbjct: 155 NFNKKKLDKLLNSEGVNVVPVINQIEAHPLLTQPDLFDYLKSKDIYITAYSPLGHADA-- 212
Query: 259 GSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFT 318
ST++ + V++ IA+K+ Q+++ W ++R + IPK+ +R+ +NI FT
Sbjct: 213 -STLK-----NKVVTDIAKKHNANAGQVLISWGVQRGTIVIPKSTTDERIIDNIK--TFT 264
Query: 319 LTPDEVEKINGFD 331
L+ ++ + +N +
Sbjct: 265 LSQEDFDALNNLE 277
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 175 bits (425), Expect = 4e-42
Identities = 91/269 (33%), Positives = 154/269 (57%), Gaps = 14/269 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + ++ + AI GYR DTA Y E ++GE ++ V R ++F+TTK
Sbjct: 22 GVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGEGIR----NSGVDRAEMFVTTK 77
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
L+N + +A ++SL +LGLDY+DLYL+HWP D++ + +++W+ E
Sbjct: 78 LFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP---TKDWNAT----IQSWKAAEKIL 130
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G + IG+ NF + QL+ ++ + P QIE+H QK ++ ++ G+V +S
Sbjct: 131 GDGRARAIGVCNFLEDQLDELIAASDVVPAVNQIELHPYFAQKPLLAKNRALGIVTEAWS 190
Query: 250 PFGSLVAR-HGSTVEGPK--IDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
P G + G G K + DPV+++IA+ +G++ Q++LRW + VV IPK+VNP+
Sbjct: 191 PIGGAINDGDGDNHGGRKHPLTDPVITTIAEAHGRSAAQVILRWHFQNDVVAIPKSVNPE 250
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTR 335
R+ +NI++FDF L+ E+ +++ DT R
Sbjct: 251 RIAKNIDVFDFALSDAEMAQLDELDTGVR 279
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 174 bits (424), Expect = 5e-42
Identities = 93/266 (34%), Positives = 148/266 (55%), Gaps = 19/266 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + D++ VV I GYR DTA +Y E G +K + + RED+F+T+K
Sbjct: 23 GVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTGAGIKAGLAATGLNREDLFVTSK 82
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
+WN E QA NDSL++LGLDY+DLYL+HWP G N+ + E+W+ LE
Sbjct: 83 VWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWP-GNNS--------YKESWQALETLY 133
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G VK IG+SNF LE +L + P Q+E+H + QKE+ +FC+ + V +S
Sbjct: 134 AEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVELHPKLDQKEVRDFCEKHDIKVQAWS 193
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P ++G + + + +IA+ + K+ Q++LRW I++ ++ K+V+ +R+
Sbjct: 194 PL----------MQGQLLSNETILAIAENHNKSAAQVILRWDIQQDILLAVKSVHKERMI 243
Query: 310 ENINIFDFTLTPDEVEKINGFDTHTR 335
N +FDF L+ +E+ +IN + R
Sbjct: 244 SNAAVFDFELSAEEMAQINQLNESLR 269
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 174 bits (423), Expect = 6e-42
Identities = 91/264 (34%), Positives = 148/264 (56%), Gaps = 15/264 (5%)
Query: 75 KDKQLR-DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNT 133
KD++ V +AI +GYRHFDTA +Y +E+ +G A+ + G V+R+D+F+T+KLW++
Sbjct: 26 KDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAISYGTVQRDDLFVTSKLWSS 85
Query: 134 QHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NADYSHSDVDFMETWRG 184
H + A+ +LK +GLDY+D YL+HWPI L D D+ ETW+G
Sbjct: 86 DHH--DPISALIQTLKTMGLDYLDNYLVHWPIKLKPGVSEPIPKEDEFEKDLGIEETWQG 143
Query: 185 LEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVV 244
+E MG+ + IG+SNF+ +++ +L ++ P Q+E+H Q+++ + C+ +
Sbjct: 144 MERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVEMHPLWRQRKLRKVCEENNIH 203
Query: 245 VMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
V GYSP G GST I+ P++ SIA K+ T Q+ LRW + + I K+ N
Sbjct: 204 VSGYSPLGGPGNCWGSTA---VIEHPIIKSIALKHNATPAQVALRWGMSKGASVIVKSFN 260
Query: 305 PKRLEENINIFDFTLTPDEVEKIN 328
R+ EN + L ++ I+
Sbjct: 261 GARMIENKRALEIKLDDQDLSLID 284
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 173 bits (422), Expect = 8e-42
Identities = 94/287 (32%), Positives = 148/287 (51%), Gaps = 26/287 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G SK ++ + V A+ GYRH D A+ Y+ E E+G K + V R+ IFIT+K
Sbjct: 21 GTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGWK----KSGVPRDQIFITSK 76
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG-------------LNADYSHSDV 176
LWNT H V +A+N +LK L DY+DLYL+HWP+ + + ++V
Sbjct: 77 LWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTPIDPVTKRFRLANV 136
Query: 177 DFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVE 236
+TW LE ++ IG+SNF + +++ +LK I P QIE H Q + +
Sbjct: 137 PIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIPPAVNQIEAHPYLQQPGLHK 196
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+ + + ++ + YSP G+ + P+ +DDP + +IA K GK +++ W ++R
Sbjct: 197 YLKEKNILSVAYSPLGN------NIYNAPRVVDDPDVKAIADKLGKDPAALLISWAVQRG 250
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW 342
+PK+V P R+E N DF + E E +N D + RY P W
Sbjct: 251 TAVLPKSVTPSRIESNFQ--DFIIPDAEFEALNKLDRNQRYNFPFRW 295
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 173 bits (421), Expect = 1e-41
Identities = 96/262 (36%), Positives = 149/262 (56%), Gaps = 20/262 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + + V A+D+GYRH DTA +Y E E+ + + + GV R++I++T+K
Sbjct: 29 GVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEVAQGI---ADSGV-PRDEIWVTSK 84
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
L N H +A++DS++KL IDLYL+HWP L Y DF+ TW+ LE+A+
Sbjct: 85 LNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHWP--LPTLYGG---DFVSTWKVLEEAR 138
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G ++ IG+SNF L+R+ +E T+ P QIEVH +E+ C + V +S
Sbjct: 139 AAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQIEVHPYFGNEEVRRHCGEHQIGVEAWS 198
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P +G +DDP ++++A + GK+ Q+VLRW +ER + PK+V P R+E
Sbjct: 199 PIA----------QGKVLDDPTVTAVANRLGKSPAQVVLRWHVERGDIVFPKSVTPSRME 248
Query: 310 ENINIFDFTLTPDEVEKINGFD 331
EN +FDF LT +++ I+ D
Sbjct: 249 ENFALFDFELTEEDLALISALD 270
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 173 bits (420), Expect = 1e-41
Identities = 101/270 (37%), Positives = 148/270 (54%), Gaps = 20/270 (7%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQH 135
D Q+ V+ A++ GYRH DTA Y E+ +G ++ + R ++FITTKL
Sbjct: 27 DHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNGIR----SSGLDRSELFITTKLDGEFQ 82
Query: 136 RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVK 195
+ ++ SLK+LGLDY+DL L+HWP+ D +F+ TW+ E Q G V+
Sbjct: 83 GQDRAVAGLDGSLKRLGLDYVDLLLIHWPL------PRRD-EFISTWKTFERLQADGKVR 135
Query: 196 GIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLV 255
IG+SNF LER++ + P QI+V + + + + G+V YSP G+
Sbjct: 136 SIGVSNFKPAHLERLMAACDVVPAVNQIQVSPAITRIVDIAYNRRHGIVTESYSPLGA-- 193
Query: 256 ARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIF 315
GS + ++ PVL IAQK+GKT QIVLRW +E+ +V IPKT NP+R++EN++IF
Sbjct: 194 ---GSDL----LNAPVLGRIAQKHGKTPGQIVLRWHVEQGLVAIPKTANPQRMKENLDIF 246
Query: 316 DFTLTPDEVEKINGFDTHTRYTLPSFWQNH 345
FTL D+ I D + S Q H
Sbjct: 247 GFTLDADDTSAIATLDGGDESGVNSDVQGH 276
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 172 bits (418), Expect = 3e-41
Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 26/274 (9%)
Query: 58 EAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG 117
E P G+FQ + + D+ ++ V AI GYR DTA Y + +GEA+K
Sbjct: 14 EIPQLGFGVFQ---ISNHDEAVK-AVESAISNGYRLIDTAEAYNNQTAVGEAIK----NS 65
Query: 118 VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVD 177
V R+DIF+TTKLW + + ++AI++ LK+LG DYID+ L+H G D
Sbjct: 66 DVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLHQAYG----------D 115
Query: 178 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 237
WR LEDAQ+ G K IG+SNF QL + +KP QIEV+ ++ V++
Sbjct: 116 VAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIEVNPWFQREPEVKW 175
Query: 238 CQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVV 297
Q + V V ++PF + G +PVL+ I +KYGK+ Q++LRW I+R ++
Sbjct: 176 NQKDDVAVEAWAPFAE--GKDGI------FTNPVLTEIGKKYGKSNGQVILRWLIQRGII 227
Query: 298 PIPKTVNPKRLEENINIFDFTLTPDEVEKINGFD 331
IPK+V+ R +ENI+IFDF L D+++KI D
Sbjct: 228 VIPKSVHDARQKENIDIFDFELNNDDMQKIAALD 261
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 172 bits (418), Expect = 3e-41
Identities = 90/263 (34%), Positives = 148/263 (56%), Gaps = 23/263 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + D + A + GYR DTA +Y E+ +G A++ + R++++ITTK
Sbjct: 76 GVWQMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGVGRAIRASG----LPRKELYITTK 131
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVD-FMETWRGLEDA 188
+WN+ +A+ +SL +L L+Y+DLYL+HWP+ +D +++TW+ L
Sbjct: 132 VWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPV--------PKIDRYVDTWKALAKI 183
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
+ G+ + IG+SNF L+R+ E I P Q+E+H + Q E+ F +V +
Sbjct: 184 KADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVELHPRLQQHELRAFHAKHRIVTEAW 243
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SP G +G + DPVL+ IAQK+G++ Q+++RW I++ +V IPK+V P R+
Sbjct: 244 SPLG----------QGTLLADPVLAGIAQKHGRSAAQVIIRWHIQQGLVVIPKSVTPSRI 293
Query: 309 EENINIFDFTLTPDEVEKINGFD 331
EN N+FDFTL +++ I D
Sbjct: 294 AENANVFDFTLDAEDMAAIASLD 316
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 172 bits (418), Expect = 3e-41
Identities = 100/291 (34%), Positives = 158/291 (54%), Gaps = 22/291 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G K + K + + +AI +GYR FD A Y E E+G + ++EG+VKRE++FI TK
Sbjct: 21 GCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTK 80
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN-----ADYS------HSD-VD 177
LWNT H + V A + LK GL+Y DLYL+H+PI L Y H+D ++
Sbjct: 81 LWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLN 140
Query: 178 FM-----ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQK 232
F E W +E + + + IG++NFN Q + +L IKP +QIE+H Q+
Sbjct: 141 FERSPIHECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQE 200
Query: 233 EMVEFCQSEGVVVMGYSPFGSL----VARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL 288
+V++ Q +G+ V YS FG + G T + + + SIA K+ T QI+L
Sbjct: 201 RLVKWVQEQGIQVTAYSSFGPTSYVDLCESGKTYSS-LLANADVKSIANKHNANTGQILL 259
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
R+ ++R + IPK+V+ R++ N++I + L D+ + +N T+ R+ P
Sbjct: 260 RYALDRNIAVIPKSVHEDRMKSNLDILNIQLDQDDRKILNSLKTNQRFNDP 310
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 171 bits (417), Expect = 3e-41
Identities = 93/278 (33%), Positives = 149/278 (53%), Gaps = 12/278 (4%)
Query: 58 EAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG 117
+ G + + GV ++ + V A+ +GYRH DTA+ Y E+E+GE ++
Sbjct: 23 DGSGVEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIR----RA 78
Query: 118 VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVD 177
+ R+++FI TK+W + + E A + S KLG+D IDL L+H P+ D +
Sbjct: 79 GIARDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRT----- 133
Query: 178 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 237
+ +R LE G V+ IG+SNF + L R+L E +I P QIEVH Q+ +
Sbjct: 134 -LGAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRL 192
Query: 238 CQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVV 297
G++ +SP G + G E ++DPVL IAQ++GK+ Q++LRW ++
Sbjct: 193 HAEHGILTQAWSPIGGITFYRGG--EKSTLEDPVLLEIAQQHGKSAAQVMLRWHLQEGRS 250
Query: 298 PIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR 335
IPK+ P R+ EN ++FDF L+ +++ I+ DT R
Sbjct: 251 VIPKSTKPARIAENFDVFDFELSGEQIAAIDALDTGVR 288
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 171 bits (416), Expect = 4e-41
Identities = 100/268 (37%), Positives = 156/268 (58%), Gaps = 24/268 (8%)
Query: 64 CGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV-EEGVVKRE 122
CG+ GV Q +V +A+DVGYR DTA YE E+E GE +K + ++ KRE
Sbjct: 21 CGV---GVYLLPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGIKAWLGKDKNNKRE 77
Query: 123 DIFITTKLWNTQHRRTEVAQAINDSLKKLG-LDYIDLYLMHWPIGLNADYSHSDVDFMET 181
D+ TTK+ N +++ +SL K+ L+YIDL L+H P+ +ET
Sbjct: 78 DVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLS-------DKKTRIET 130
Query: 182 WRGLEDAQRMGIVKGIGLSNFNKQQLERVLK-EGT-IKPDAIQIEVHLQNVQKEMVEFCQ 239
W+ L++A G+VK IG+SNF K ++ + EG KP QIE+ ++K++V++CQ
Sbjct: 131 WKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIELSPWLMRKDLVDYCQ 190
Query: 240 SEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPI 299
+ G+V+ Y P + G K++DP L +A+KY KT Q++LRW I+R VV I
Sbjct: 191 NLGIVLEAYCPLTT----------GAKLNDPTLVKLAKKYNKTPAQVLLRWNIDRGVVVI 240
Query: 300 PKTVNPKRLEENINIFDFTLTPDEVEKI 327
PK++ P+RL +N ++FDF LT ++ ++
Sbjct: 241 PKSLKPERLPQNFDLFDFKLTDEDFAEL 268
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 171 bits (416), Expect = 4e-41
Identities = 93/266 (34%), Positives = 151/266 (56%), Gaps = 21/266 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV ++ ++ V +A++VGYR DTA++Y+ E+ +G+A+K V R+++FITTK
Sbjct: 21 GVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKALKA----AAVARDELFITTK 76
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
LWN + QA+ SL+KL LDY+DLYL+HWP + H ++ WR L +
Sbjct: 77 LWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP---DPKQDH----YVSAWRELVTLK 127
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G+++ IG+ NF+ L+R++ E I P QIE+H Q+++ + + + +S
Sbjct: 128 EQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAWNATHHIATESWS 187
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P +A+ G V D ++ +AQ+Y KT QIV+RW ++ ++ IPK+V P R+
Sbjct: 188 P----LAQGGKGV----FDQEIIRKLAQQYNKTPAQIVIRWHLDSGLIVIPKSVTPARIR 239
Query: 310 ENINIFDFTLTPDEVEKINGFDTHTR 335
EN +FDF L +E+ I D R
Sbjct: 240 ENFEVFDFKLQKEELLAITKLDCGKR 265
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 171 bits (415), Expect = 6e-41
Identities = 95/266 (35%), Positives = 148/266 (55%), Gaps = 20/266 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + D + V A++ GYR DTA++Y E+ G A+ G+ RED+F+TTK
Sbjct: 22 GVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGRAI---AASGLA-REDLFVTTK 77
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
LWN+ +A + S+ KLGL+Y+DLYL+HWP+ Y ++T++ E
Sbjct: 78 LWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAKERY-------VDTYKAFEKLL 130
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G V+ IG+SNF + LER+ E ++ P QIE+H Q E +G+ +S
Sbjct: 131 ADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQIELHPHLQQHAAREVHAEQGIATEAWS 190
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P GS G + +D P + +IAQK+G+T Q+VLRW ++ V IPK+V P R++
Sbjct: 191 PLGS-----GKGI----LDIPAIVAIAQKHGRTPAQVVLRWHLQLGNVVIPKSVTPSRIK 241
Query: 310 ENINIFDFTLTPDEVEKINGFDTHTR 335
ENI++F F+L +++ I+ + R
Sbjct: 242 ENIDVFGFSLDTEDLAAISALNEDRR 267
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 171 bits (415), Expect = 6e-41
Identities = 117/337 (34%), Positives = 183/337 (54%), Gaps = 45/337 (13%)
Query: 21 MEVPSLKMNNGRDMPAIGLGTYLGFDQAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLR 80
M VP +K++NG ++PAIG G S T+ PG++ ++++L
Sbjct: 1 MTVPKVKLSNGLEIPAIGFG----------SGTKWK-RPPGEK-----------EERELI 38
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK-LWNTQHRRTE 139
D V+ AI+ G+ H DTA Y TE++IGEA+K E V R+DIF+T+K L+ +
Sbjct: 39 DAVVSAINAGHLHIDTAEFYGTEKQIGEAIK----ESGVPRKDIFLTSKTLFGLL--ADD 92
Query: 140 VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGL 199
++I++ LK L DY DL+L+H P + +Y D + W LE G+ K IG+
Sbjct: 93 PIESISNQLKTLQTDYFDLFLIHVPPNDDINY-----DLAKAWGVLEQLYEKGLAKAIGV 147
Query: 200 SNFNKQQLERVLKEGTIKPDAIQIEVH--LQNVQKEMVEFCQSEGVVVMGYSPFGSLVAR 257
SN + +LE ++K IKP QIE H LQ +V+FC+ +VV GYSP S
Sbjct: 148 SNHSPAELETIIKVAKIKPHVNQIEFHPLLQEPTPGIVDFCKQHDIVVEGYSPLAS---- 203
Query: 258 HGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDF 317
+ +EG K D V++++A+ + + ++LRW ++ +VPI + N R +E + IFDF
Sbjct: 204 --NELEGEKPLDAVVANVAKNHNVSPGSVLLRWATQKGIVPITTSANAGRQKEALAIFDF 261
Query: 318 TLTPDEVEKIN--GFDTHTRYTLPSFWQNHPYYPFDK 352
L+ EVE+I+ G ++ LP H YYP ++
Sbjct: 262 KLSDGEVEEISKVGAESPRYQRLPIPSHKH-YYPAEE 297
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 171 bits (415), Expect = 6e-41
Identities = 104/293 (35%), Positives = 153/293 (52%), Gaps = 23/293 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G +S+ Q ++ V A+ GYRH D A++Y E E+G+ +K E V R+DI++T+K
Sbjct: 30 GTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK----ESGVPRKDIWVTSK 85
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DYSHSDVD---------F 178
LW H V +A+ +LK L LDY+D YL+HWP+ D D D
Sbjct: 86 LWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGNLIYEKNPI 145
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFC 238
ETW+ +E G V+ IGLSNFN LER+LK +KP Q+E+H Q E VE
Sbjct: 146 EETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVEKH 205
Query: 239 QSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGK--TTPQIVLRWQIERK 295
+ G+ V YSPFG+ + S + PK I+ + IA+ G+ T I + W I R
Sbjct: 206 KKLGIHVTAYSPFGNQNTIYESKI--PKLIEHETIQKIAKSKGEGVTGATIAVSWAITRG 263
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYY 348
IPK+VN +R++ N LT +++++IN R+ +F N P +
Sbjct: 264 TSVIPKSVNEQRIKSNFKY--IPLTKEDMDEINSIGIRARFNQATF-SNEPVF 313
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 170 bits (414), Expect = 8e-41
Identities = 103/308 (33%), Positives = 164/308 (53%), Gaps = 27/308 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G K K + + AI +GYR FD A Y E+E+GE ++ + EG+V R+DIF+ +K
Sbjct: 19 GCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVSRKDIFVVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN---------------AD---- 170
LWN H V A+ +L +GLDY+DLY +H+PI AD
Sbjct: 79 LWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKK 138
Query: 171 --YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ + V ++T+R LE+ G++K IG+SNF ++ +L+ IKP A+QIE H
Sbjct: 139 GHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPY 198
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFG--SLVARHGSTVE-GPKI-DDPVLSSIAQKY-GKTT 283
Q+ +VEFC+ + V+ YS FG S + + P + ++ V+ ++Q + G TT
Sbjct: 199 LTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTT 258
Query: 284 PQIVLRWQIERKVVPIPKTVNPKRLEENINI-FDFTLTPDEVEKINGFDTHTRYTLPSFW 342
Q++LRW +R + IPK+ +RL N+ I FTLT E++ I+ + + R+ P W
Sbjct: 259 SQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISALNANIRFNDPWTW 318
Query: 343 QNHPYYPF 350
+ + F
Sbjct: 319 LDGKFPTF 326
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 170 bits (414), Expect = 8e-41
Identities = 101/276 (36%), Positives = 159/276 (57%), Gaps = 35/276 (12%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
+ + V AI GYRH DTA YETE +GEA+K +E+G +KRED+FITTK+W
Sbjct: 49 ETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW-- 106
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPI---------GLN------ADYS-----HSDVD 177
EV +++N+SLK LGL+Y+DL L HWP+ G++ D S +D D
Sbjct: 107 DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGD 166
Query: 178 FMETWRGLEDA---QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEM 234
++ET++ LE V+ IG+SNF+ + LER++KE +KP Q+E H Q E+
Sbjct: 167 YLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMEL 226
Query: 235 VEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIER 294
+FC +++ YSP GS HG+ P + P++ +A+KY T +++ + I +
Sbjct: 227 RKFCFMHDILLTAYSPLGS----HGA----PNLKIPLVKKLAEKYNVTGNDLLISYHIRQ 278
Query: 295 KVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGF 330
+ IP+++NP R+ +I +LT DE++++N F
Sbjct: 279 GTIVIPRSLNPVRISSSIEF--ASLTKDELQELNDF 312
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 170 bits (413), Expect = 1e-40
Identities = 94/267 (35%), Positives = 143/267 (53%), Gaps = 24/267 (8%)
Query: 70 GVVKSKDKQ-LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
GV K D+Q +R + A+DVGYR FDTAS Y E+E+G+ G+ KR++ F+TT
Sbjct: 23 GVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFF---ASSGL-KRDEFFVTT 78
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDA 188
K+WNT+ E +A S KKL LD +DLYL+HWP F ETWR +E
Sbjct: 79 KMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---------KQDTFFETWRAVEKL 129
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
G+V+ IG+SNF L+R+ + P Q+E H + + + + +V +
Sbjct: 130 YDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFPNQLLHRYLEELHIVHQAW 189
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SP G G + + +L +A+K+GK+ QIVLRW ++ + IPK+ P R+
Sbjct: 190 SPLG----------RGGVLQEQILIDLAKKHGKSPAQIVLRWHLQNNISIIPKSETPSRI 239
Query: 309 EENINIFDFTLTPDEVEKINGFDTHTR 335
EN +I+DF LT ++ ++ + R
Sbjct: 240 RENADIYDFELTEADMRQVERLNNGER 266
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 170 bits (413), Expect = 1e-40
Identities = 93/263 (35%), Positives = 144/263 (54%), Gaps = 23/263 (8%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
A+ G+RHFD A Y E+E+GEA++ G + RE+IF+TTKLWNT HR V A
Sbjct: 42 ALAAGFRHFDCAERYRNEREVGEALRAGRAAGNIAREEIFVTTKLWNTNHRPERVEPAFE 101
Query: 146 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSD-VDFMETWRGLEDAQRMGI 193
SL +LGLDY+DLYL+H P N + + V ETW LE+ G
Sbjct: 102 ASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQNGSVIYDEGVTLRETWSALENLVDRGR 161
Query: 194 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 253
+ IGLS+ + +L + + IKP +Q+E H + E++EFC+ G+V++ ++P G
Sbjct: 162 CRAIGLSDISMDRLAPIYEAARIKPAVVQVESHPYLPETELLEFCKRNGIVLLAFAPLG- 220
Query: 254 LVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENIN 313
HG + ++DPV++S++++ GKT Q++L W ++R + + R +EN
Sbjct: 221 ----HG--MRPGLLEDPVITSVSERVGKTAAQVLLSWAVQRGTALLTTPRSAARAKEN-- 272
Query: 314 IFDFTLTPDEV-EKINGFDTHTR 335
FD + P+E +IN T R
Sbjct: 273 -FDISPLPEEAFNEINRIQTRQR 294
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 170 bits (413), Expect = 1e-40
Identities = 94/262 (35%), Positives = 144/262 (54%), Gaps = 19/262 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV K + V A++VGYRH DTA++Y E+ +G A+ G+ R+D+FITTK
Sbjct: 20 GVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAI---AASGIA-RDDLFITTK 75
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
LWN +H E A AI +SL KL LD +DLYL+HWP +Y H+ W + + +
Sbjct: 76 LWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAADNYVHA-------WEKMIELR 128
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G+ + IG+SN LER++ + P QIE+H Q+E+ ++ + V + +
Sbjct: 129 AAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWG 188
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P G ++ P +++ A +GKT Q VLRW +++ V PK+V +RLE
Sbjct: 189 PLGQ--GKYDLFGAEP------VTAAAAAHGKTPAQAVLRWHLQKGFVVFPKSVRRERLE 240
Query: 310 ENINIFDFTLTPDEVEKINGFD 331
EN+++FDF LT E+ I+ D
Sbjct: 241 ENLDVFDFDLTDTEIAAIDAMD 262
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 169 bits (411), Expect = 2e-40
Identities = 95/260 (36%), Positives = 144/260 (55%), Gaps = 24/260 (9%)
Query: 70 GVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
G+ K+ D + D + A+ GYR DTAS Y+ E+ +G + + V R+D+FITT
Sbjct: 7 GLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVG----CGIAKCGVPRKDLFITT 62
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDA 188
K+WN R +V A SL +LGLDYIDLYL+HWP+ F+ TW+ +E
Sbjct: 63 KIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPV---------PGCFLNTWKDMEKI 113
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
G IG+SNF + LE + + I P QIE H KE++E+CQ+ + V Y
Sbjct: 114 LESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEYCQANDIQVQAY 173
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
+P +AR G +D+ VL + KY T QI LRW +++ + IPK+V+P+R+
Sbjct: 174 AP----LAR------GAYLDNDVLCVLGTKYAHTPAQIGLRWAVQKGISVIPKSVHPERI 223
Query: 309 EENINIFDFTLTPDEVEKIN 328
N IFDFT+ ++++ ++
Sbjct: 224 ASNARIFDFTIDQEDMDLLD 243
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 169 bits (410), Expect = 2e-40
Identities = 89/218 (40%), Positives = 125/218 (57%), Gaps = 12/218 (5%)
Query: 145 NDSLKKLGLDYIDLYLMHWPIGLNADYS-H-----------SDVDFMETWRGLEDAQRMG 192
++SLK L LDY+D+YLMHWP L S H SDVDF++TW+ +E
Sbjct: 270 SESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKD 329
Query: 193 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
+ K IG+SNFN Q++R+LK I P QIE H Q ++ +FC G+ V YSP G
Sbjct: 330 LTKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLG 389
Query: 253 SLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENI 312
S + I+DP + I KYGK+ QI+LR+ ++ V IPK+ N RL EN+
Sbjct: 390 SPARPWQKPGDPYVINDPKIKEIGNKYGKSPAQILLRYNVQLGNVVIPKSSNRNRLVENM 449
Query: 313 NIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+IFDFTL+ D+++ I FD + R + + HP+YPF
Sbjct: 450 SIFDFTLSEDDMKYIGTFDCNGRICPQAEAREHPFYPF 487
Score = 137 bits (332), Expect = 7e-31
Identities = 82/253 (32%), Positives = 136/253 (53%), Gaps = 17/253 (6%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V + YR D S++E E+ G A++ +E G ++R+D+F+ +K T V
Sbjct: 36 VQLVVSSNYRLMD-CSIFENEKRFGVALQQLIEGGKIRRKDLFLMSKFCCTNTTNL-VKA 93
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
A+ D+LKKL + Y+DLYL+ P D + +ETW +E + + IGLSNF
Sbjct: 94 ALLDTLKKLQVAYLDLYLIERPPACK------DHNLIETWEAMEGLYSEKLTRAIGLSNF 147
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
N +Q+ER+L+ TI+P QI+ H Q ++ ++C + G+ V+ YSP G AR+
Sbjct: 148 NSKQIERILENCTIRPQVNQIQCHPYLNQAKLRKYCSNNGIAVISYSPLG---ARNNIQP 204
Query: 263 EG-PKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTP 321
E + D + IA++Y KT +IVL++ ++ + V L E+ N FDF L P
Sbjct: 205 ESLDVLSDCRIKEIARRYNKTPTEIVLKYNVQ-----LGNIVISDMLIESANFFDFYLAP 259
Query: 322 DEVEKINGFDTHT 334
+++ I+ F + +
Sbjct: 260 EDMSYISTFSSES 272
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 169 bits (410), Expect = 2e-40
Identities = 96/267 (35%), Positives = 155/267 (58%), Gaps = 10/267 (3%)
Query: 77 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHR 136
+++ ++ A+D GYR+FDTA Y E EIG+A + ++G KRED+FITTKL+ +
Sbjct: 42 EEMTTLLSNALDFGYRNFDTAKQYRNEVEIGQAFQNIFQQGKYKREDVFITTKLFPFKIE 101
Query: 137 RTEVAQAINDSLKKLGLDYIDLYLMHW---PIGLNADYSHS--DVDFMETWRGLEDAQRM 191
+ ++ + + +SL +L YIDLYL+ W P+ N D S + E WR LE+ +
Sbjct: 102 K-KIKEVVQNSLDQLQTSYIDLYLIQWSFTPVLTNFDGSVAVNHRPIHEVWRELEECVEL 160
Query: 192 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 251
G+++ IG++NFN Q + +L IKP QIEV Q +++ F + + + SP
Sbjct: 161 GMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIEVTPYLPQIDLINFLKRCKIETVAISPL 220
Query: 252 GSLVARHGSTVEGPKI---DDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
G +T EG KI ++ + IAQK+ K+ Q++LR ++R+++ IPKT RL
Sbjct: 221 GR-AGCFENTPEGMKIKLLEEDIFKQIAQKHKKSVVQVILRCLVQREIMMIPKTAKLDRL 279
Query: 309 EENINIFDFTLTPDEVEKINGFDTHTR 335
+EN IFDF LT +++++I + TR
Sbjct: 280 KENSEIFDFELTEEDMKQIYSLENGTR 306
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 168 bits (409), Expect = 3e-40
Identities = 100/264 (37%), Positives = 145/264 (54%), Gaps = 20/264 (7%)
Query: 70 GVVKSKDKQL-RDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
GV + DK + + V+ AI GYR DTA+VY E +GEAV+ + EG+ RE++FIT+
Sbjct: 23 GVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELFITS 82
Query: 129 KLWNTQHRRTEVAQA-INDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLED 187
KLW ++A A I SLKK GL+Y DLYL+H + D+ WR LED
Sbjct: 83 KLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR----------DYFSAWRALED 132
Query: 188 AQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
A G +K IG+SNF L + +KP Q+E+H Q E + + V
Sbjct: 133 AYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELHPYFAQPEALATMKYYNVQPEA 192
Query: 248 YSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKR 307
++P G RH ++ +L SIA + K+ Q++LRW I+R VV IPK+ + +R
Sbjct: 193 WAPLGG--GRH------KPFENNLLQSIADAHQKSISQVILRWNIQRGVVVIPKSTHQQR 244
Query: 308 LEENINIFDFTLTPDEVEKINGFD 331
+EEN I+DF+LT E+ +I+ D
Sbjct: 245 IEENFAIWDFSLTEKEMAQISSLD 268
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 168 bits (409), Expect = 3e-40
Identities = 99/291 (34%), Positives = 149/291 (51%), Gaps = 24/291 (8%)
Query: 46 DQAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 105
+ AG+ S L+ G + GV + + + V A++ GYR DTA+VY E
Sbjct: 7 EAAGIPSVSLN---DGHSIPVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAA 63
Query: 106 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 165
+G AV + RE+I++TTKL A SL++LGLDY+DLYL+HWP
Sbjct: 64 VGRAVNASG----IPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWPA 119
Query: 166 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 225
G + Y +++W GL A++ G+ + IG+ NFN + L ++ P QIE+
Sbjct: 120 GDHGKY-------IDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQIEL 172
Query: 226 HLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQ 285
H Q E+ E G+V Y P G G +D ++ +AQ +GKT Q
Sbjct: 173 HPLLNQAELREVNAGYGIVTEAYGPLGV----------GRLLDHAAVTGVAQAHGKTPAQ 222
Query: 286 IVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRY 336
++LRW I+ V I ++ NP R+ N+ +FDF LT DE+ +NG D TR+
Sbjct: 223 VLLRWSIQLGNVVIARSANPDRITSNLEVFDFELTDDEMATLNGLDEGTRF 273
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 168 bits (409), Expect = 3e-40
Identities = 96/264 (36%), Positives = 147/264 (55%), Gaps = 16/264 (6%)
Query: 79 LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV-KREDIFITTKLWNTQHRR 137
L + A+ +GYRH DTA+VY TE +G AV V G V R ++F+TTKL
Sbjct: 47 LAATIAHAVRLGYRHLDTAAVYGTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHP 106
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA----------DYSHSDVDF-ME-TWRGL 185
V A+ +SL +LGLDY+DL+L+HWP+ + D S V F ME WRG+
Sbjct: 107 PRVVAALRESLSRLGLDYVDLFLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGM 166
Query: 186 EDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVV 245
E+ R+G+ + IG+SNF+ ++ R+L + P Q+E+++ Q+++ E C GVVV
Sbjct: 167 EECHRLGLARSIGVSNFSAAKMSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVV 226
Query: 246 MGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNP 305
YSP G+ A GS ++ VL +A KT Q+ LRW E+ V + ++ N
Sbjct: 227 AAYSPLGAHGAHWGSDA---VMNSGVLHDVAAARCKTIAQVALRWLYEQGVCMVARSFNE 283
Query: 306 KRLEENINIFDFTLTPDEVEKING 329
R+++N++IFD+ L+ + I G
Sbjct: 284 GRMKQNMDIFDWELSDQDKAMIAG 307
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 168 bits (408), Expect = 4e-40
Identities = 101/293 (34%), Positives = 164/293 (55%), Gaps = 16/293 (5%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMR-AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV 119
G + +F G K K+ +R A+D+GYRH DTA +YE E++IG+A++ +EG
Sbjct: 13 GSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIYKEGKY 72
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD-YSHSDVDF 178
KRED+F+ TKL++ ++ T+V + SL+ L +YIDLYL+H+ D + +
Sbjct: 73 KREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSPPTDQFELTHKPV 130
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFC 238
+ W E+ + G+++ IG+SNFN Q L + IKP QIEV++ Q ++EFC
Sbjct: 131 FQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIEVNVYCQQPRLLEFC 190
Query: 239 QSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVP 298
+ + V Y P +AR +T +D +L+ ++ KY K+ QI+L++ + V
Sbjct: 191 KKLNLHVTAYCP----LARCQNT-----DNDALLTELSTKYKKSVCQIMLQFLLSLGVSV 241
Query: 299 IPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP---SFWQNHPYY 348
IPKT N +RL ENI DF+L ++ K+ G + + R P +W+ PY+
Sbjct: 242 IPKTQNLERLRENIESTDFSLDEADIAKLKGLNKNFRLIDPYDREWWKRVPYF 294
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 168 bits (408), Expect = 4e-40
Identities = 92/249 (36%), Positives = 136/249 (54%), Gaps = 16/249 (6%)
Query: 81 DVVMRAI-DVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTE 139
+ V+ A+ + G RH DTA Y E+ +G+AV E GV +RE++++TTKLW +
Sbjct: 40 EAVLYALQECGIRHIDTAKRYGCEEALGKAV---TESGV-QREELWVTTKLWPGDYGYQS 95
Query: 140 VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGL 199
QA DS +LG+DY+DLYLMHWP + S +V +ETWR LE+ G+ + IG+
Sbjct: 96 TKQACRDSRARLGVDYLDLYLMHWPDSMVPGRSSQEVR-LETWRALEELYDEGLCRAIGV 154
Query: 200 SNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHG 259
SNF L + G I P Q+E H ++VE C+ E +V GY P
Sbjct: 155 SNFLIPHLNELKDSGGIVPHVNQVEFHPFQQPMKLVEHCRKENIVFEGYCPL-------- 206
Query: 260 STVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTL 319
+G + P + +A+KYG++ QI +RW I+ VV IPK+ P R+ EN +F F L
Sbjct: 207 --AKGQALTHPHILELAKKYGRSASQICIRWSIQNGVVTIPKSTKPDRIYENCQVFGFRL 264
Query: 320 TPDEVEKIN 328
E+ ++
Sbjct: 265 EDSEMAALS 273
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 168 bits (408), Expect = 4e-40
Identities = 100/294 (34%), Positives = 164/294 (55%), Gaps = 26/294 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV K+ + + +V AI Y DTA Y E +G+ ++ + KR+ IF+TTK
Sbjct: 27 GVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDGFKATGRKRDSIFLTTK 86
Query: 130 LWN-TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDA 188
++N Q ++ QA+N+ LKKL +Y+DL L+HWP+ N Y+ E+WR LED
Sbjct: 87 IFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPV--NDKYN-------ESWRALEDI 137
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
+ G K IG+ NFN +++ +L IKP QIE + Q ++V+FC+ + + +
Sbjct: 138 YKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIEFNPLIHQPKIVKFCRENDIQLEAW 197
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SP G+ G + + V+ IA ++ K+ Q++LRW+I++ + + KT +P+R+
Sbjct: 198 SPLGN----------GRLLSNDVIKQIADEHQKSPAQVILRWEIQQGFIVLTKTTHPQRM 247
Query: 309 EENINIFDFTLTPDEVEKINGFD--THTRYTLPSFWQNHPYYPFDKVDNPIADP 360
+EN IFDFTL+PDE+++I+ D H+ + W +P D VD+ I P
Sbjct: 248 KENAEIFDFTLSPDEMKQIDKLDQEKHSIWYDKFKWSGNP----DGVDDYIGKP 297
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 167 bits (405), Expect = 1e-39
Identities = 94/259 (36%), Positives = 147/259 (56%), Gaps = 20/259 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G K +Q D ++RA+ GYR D+A YE E +G AV+ + G++ R++IFIT+K
Sbjct: 39 GTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGAAVR---QSGLL-RDEIFITSK 94
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
L H + + I +SL ++ DY+DLYL+HWP Y +E W+ L DAQ
Sbjct: 95 LPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWPNPQQGLY-------IEAWQALIDAQ 147
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+ G ++ IG+SNF + +E + +E + P Q+E+H Q E + +S+ ++ M +S
Sbjct: 148 KKGYIRSIGVSNFLPKHIETLRRETGVIPVINQVELHPYFNQAEQRAYDESQQIITMAWS 207
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P G A +DD VL IAQ+ +T Q+VLRWQ++ V+PIPK + +
Sbjct: 208 PLGRAKAI---------LDDAVLKQIAQETSRTVVQVVLRWQVQMGVIPIPKAASDQNQM 258
Query: 310 ENINIFDFTLTPDEVEKIN 328
N IFDF+L+ D+V++IN
Sbjct: 259 ANQAIFDFSLSDDQVQRIN 277
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 167 bits (405), Expect = 1e-39
Identities = 94/262 (35%), Positives = 143/262 (54%), Gaps = 20/262 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + D+ V AI+ GYRH DTA++Y E+ +G AV V+ G V+RE++FITTK
Sbjct: 25 GVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEAVGRAVADAVKAGDVQREELFITTK 84
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
LWN + +A +S KKLG+DY+DLYL+HWP AD F++ + + + Q
Sbjct: 85 LWNADQACGK--EAFAESQKKLGMDYVDLYLLHWPCP-QAD------SFVQAYDSMAEIQ 135
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+ G IG+ NF + L+ LK+ P QIE+H Q E + G+V +S
Sbjct: 136 QSGGATSIGVCNFYPEALD-ALKQAGHTPAVNQIEIHPGFSQAEQRSDNRDRGIVTEAWS 194
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P G +G + DP ++ IA ++G + Q ++RW I+R V IP++ +R+
Sbjct: 195 PLG----------QGQNLTDPTIAKIAAEHGVSVAQAIIRWHIQRGDVVIPRSSKVERVR 244
Query: 310 ENINIFDFTLTPDEVEKINGFD 331
+N ++F F L+ DEV I D
Sbjct: 245 QNFDVFGFELSADEVSAIEALD 266
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 165 bits (402), Expect = 2e-39
Identities = 102/294 (34%), Positives = 151/294 (51%), Gaps = 20/294 (6%)
Query: 39 LGTYLGFDQAGLSSTELSFEAP-GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 97
+ T L + A SS +F P G + G K + D V RA++VGYRH DTA
Sbjct: 1 MNTPLPAENAPASSPIPTFMLPTGSPIPVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTA 60
Query: 98 SVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 157
+Y E E+G A+ E + RED+FITTK+ N+ H A +I SL+ L DY+D
Sbjct: 61 QMYGNEAEVGAAL----EASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVD 116
Query: 158 LYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 217
L L+HWP L Y D W LEDA G + IGLSN+ ++ +E V + T+
Sbjct: 117 LLLVHWP--LPTLYGG---DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVA 171
Query: 218 PDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQ 277
P +Q+E H ++ + Q G+V +SP +AR G + DP L I
Sbjct: 172 PHVLQVESHPFFPNADLRAYAQGLGMVFEAWSP----LAR------GRAVTDPTLVEIGA 221
Query: 278 KYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFD 331
+ G Q+ LRW ++R V PKT++ +R+ N ++F F+L P++ +I+ D
Sbjct: 222 ELGVGPTQVTLRWALDRGHVVFPKTLSRERMAANFDVFSFSLDPEQTARIDALD 275
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 165 bits (402), Expect = 2e-39
Identities = 90/269 (33%), Positives = 151/269 (56%), Gaps = 16/269 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV +Q V A+ GYR DTA +Y EQ +G AV+ + + RE+IFITTK
Sbjct: 59 GVWTLTPEQTEKSVGEALKAGYRLIDTARMYRNEQAVGRAVR----DSGIPREEIFITTK 114
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
++ + A AIN+ L+ L DYIDL L+H+P D + + W+ +E
Sbjct: 115 IYGSGDYANAEA-AINERLRLLDTDYIDLLLLHYP----------DQNDTKAWKVMEQFV 163
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+ G ++ IGLSN++++ R+++ TI P +Q EVH+ N K+ F ++ G + +
Sbjct: 164 KAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVHIYNQDKQTKAFLRNYGTQMEAWY 223
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P G + +G+ + DP + S+A+KY K+ Q++LRWQ++ + IP + NP +
Sbjct: 224 PLGGRNS-YGNGGKDVLFADPTIVSLAKKYAKSPAQVLLRWQLQAGNIAIPGSSNPAHIR 282
Query: 310 ENINIFDFTLTPDEVEKINGFDTHTRYTL 338
ENI+IFDF L+ DE+ ++ D +++++
Sbjct: 283 ENIDIFDFALSDDEMATLSRLDKKSKFSV 311
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 165 bits (401), Expect = 3e-39
Identities = 98/264 (37%), Positives = 146/264 (55%), Gaps = 25/264 (9%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V AI VG+R DTA Y E+E+GE + G+ +RE +FITTK+ + R V Q
Sbjct: 58 VCHAIKVGFRLIDTAQGYGNEKEVGEGI---CRSGIDRRE-LFITTKVNTMEMRGGTVRQ 113
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
+++ SL LG DYIDL L+HWP+ H ETW+ LE+ G ++ IG+SNF
Sbjct: 114 SLDKSLADLGTDYIDLVLIHWPVK-----GH----IKETWQILEEYVDKGKIRSIGVSNF 164
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
N L+ +L+ I+P QIE+ Q ++V + +G+ V + P G V
Sbjct: 165 NPHHLDELLEYARIRPVVNQIEIEPYMTQHDVVGYTFRKGIQVEAWGPLGQGVTG----- 219
Query: 263 EGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPD 322
+DDP + IA ++GK+ Q++LRW ++R +V IP+ N +ENI IFDF L+P
Sbjct: 220 ---VLDDPAIGEIAARHGKSAAQVILRWHMQRGLVTIPRCDNDAYTDENIRIFDFELSPS 276
Query: 323 EVEKINGFDTHTRYTLPSFWQNHP 346
E+E I G + + R ++ QN P
Sbjct: 277 EMEIITGLNRNQR----AYEQNDP 296
Score = 37.1 bits (82), Expect = 1.3
Identities = 14/27 (51%), Positives = 22/27 (81%)
Query: 22 EVPSLKMNNGRDMPAIGLGTYLGFDQA 48
+VP++K+NNG +MP +G+GT+L D A
Sbjct: 28 KVPTVKLNNGMEMPQLGVGTFLVKDNA 54
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 165 bits (401), Expect = 3e-39
Identities = 96/264 (36%), Positives = 143/264 (54%), Gaps = 21/264 (7%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQH 135
++ + D V A+ G+ H D A VY E+E+G A+K E V R +FIT+K+ H
Sbjct: 30 NRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALK----EANVPRSKLFITSKV---MH 82
Query: 136 RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVK 195
+ +A+N+SL+KLG DY+DLYL+H PI + + E W+ +E A G+V
Sbjct: 83 NVDNIPEALNESLRKLGTDYLDLYLLHSPI----PFYEKKIPISEGWKAMETALGTGLVH 138
Query: 196 GIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ--NVQKEMVEFCQSEGVVVMGYSPFGS 253
+G+SNF LE +LK TI P QIE H Q K +VEFCQS+G++V GY P
Sbjct: 139 SVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAKPLVEFCQSKGIIVEGYGPLSP 198
Query: 254 LVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENIN 313
LV +GP + S+ KY + QI+L+W + V+PI T +R++E +N
Sbjct: 199 LV----RDAQGPVAE--FTKSLESKYHVSDTQILLKWAYSKGVIPITTTSKIERMKECLN 252
Query: 314 IFDFTLTPDEVEKIN--GFDTHTR 335
FTL +++++ G H R
Sbjct: 253 FDSFTLDKADIDELGTLGVQHHKR 276
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 165 bits (401), Expect = 3e-39
Identities = 94/272 (34%), Positives = 146/272 (53%), Gaps = 28/272 (10%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
AI+ GYRH D A VY + E+G A+K E VKRED+FIT+KLWN HR +V A++
Sbjct: 35 AIETGYRHLDLAKVYSNQPEVGAAIK----EAGVKREDLFITSKLWNNSHRPEQVEPALD 90
Query: 146 DSLKKLGLDYIDLYLMHWPIGL--NADYSHS--------------DVDFMETWRGLEDAQ 189
D+LK+LGL+Y+DLYL+HWP+ D + + +V ++TW+ +
Sbjct: 91 DTLKELGLEYLDLYLIHWPVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLL 150
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G VK IG+SNF+ + ++ +++ + P QIE H +Q E++ +++ + + YS
Sbjct: 151 DTGKVKAIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYS 210
Query: 250 PFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
P G+ +TV P + P + IA+K G T Q+++ W I IPK+V P R+
Sbjct: 211 PLGN------NTVGAPLLVQHPEIKRIAEKNGCTPAQVLIAWAIVGGHSVIPKSVTPSRI 264
Query: 309 EENINIFDFTLTP-DEVEKINGFDTHTRYTLP 339
EN + D V K+ RY +P
Sbjct: 265 GENFKQVSLSQEDVDAVSKLGEGSGRRRYNIP 296
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 165 bits (400), Expect = 4e-39
Identities = 81/253 (32%), Positives = 147/253 (58%), Gaps = 13/253 (5%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
A+ GYR FDTA+VY E +G A++ + + + RED+FIT+KL + + ++
Sbjct: 39 ALKAGYRAFDTAAVYRNEAHLGHALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQ 97
Query: 146 DSLKKLGLDYIDLYLMHWP--IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFN 203
SL++LGL YIDLYL+HWP GL + + ++WR LE+ G + IG+SN+
Sbjct: 98 KSLEQLGLGYIDLYLIHWPGTQGLPVGDKRNPENRAQSWRVLEEFYSEGKFRAIGVSNYT 157
Query: 204 KQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVE 263
+ ++ +LK + P +Q+E H + +Q ++ C+ GV YS G+
Sbjct: 158 VEHMQELLKSCKVPPAVLQVEFHPKLLQNDLRGLCKIRGVCFQAYSSLGT---------- 207
Query: 264 GPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDE 323
G + +PV+ IA++ G+T Q++LRW +++ + +PK+ P+R++EN +FDF ++ ++
Sbjct: 208 GLLLSNPVVLEIAKECGRTPAQVLLRWAVQQSIAVLPKSSQPERVKENGRLFDFEISEED 267
Query: 324 VEKINGFDTHTRY 336
+E+++ D ++
Sbjct: 268 MERLSALDCGEKF 280
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 165 bits (400), Expect = 4e-39
Identities = 91/285 (31%), Positives = 153/285 (53%), Gaps = 29/285 (10%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G ++K ++R V A+ GYRH D A Y+ E E+G +K + V R +IF+T+K
Sbjct: 53 GTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDEVGLGIK----DSGVPRSEIFLTSK 108
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS--------------D 175
+W++ H R E + ++ +LK L DY+DLYL+HWP+ L + +H D
Sbjct: 109 VWSSYHDRVE--ECLDTTLKSLQTDYLDLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWD 166
Query: 176 VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMV 235
D +TW +ED + G K IGLSN +E ++K G + P Q+E+H Q ++
Sbjct: 167 WDQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALL 226
Query: 236 EFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
++C+ +G+++ YSP GS P +DP L ++A+K+ T +++ +Q+ R
Sbjct: 227 KYCKEKGILLEAYSPLGS--------TSSPLHEDPDLLAVAKKHNVPTATVLISYQVNRG 278
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTP-DEVEKINGFDTHTRYTLP 339
VV +PK+V P R+E N+ ++++K+ TR+T P
Sbjct: 279 VVVLPKSVTPARIESNLKTIKLDEEDMNKLDKLAEGGKQTRFTAP 323
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 165 bits (400), Expect = 4e-39
Identities = 93/267 (34%), Positives = 143/267 (53%), Gaps = 18/267 (6%)
Query: 67 FQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFI 126
F GV + DK+ D V A++ GYRH DTA YE E G+A+ ++ RE+IF+
Sbjct: 44 FGLGVYEMNDKETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKATGTSREEIFL 103
Query: 127 TTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLE 186
T+KL N + SLK+ G++Y DLYLMH IG V W+ L
Sbjct: 104 TSKLKNNSSYEQAFVD-LKGSLKRSGVEYFDLYLMHSAIG-------GPVIRKNVWKALC 155
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 246
DAQ G+VK IG+SNF K+ ++ + + P Q+++H E+VE C+ +++
Sbjct: 156 DAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPEIVEICEQNEILLE 215
Query: 247 GYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
+ P + + D PV+ IA++ GK QI+LRW I+ V IPK+V+ K
Sbjct: 216 AWGPLARAM----------RFDHPVVVKIAKEKGKDAAQIMLRWGIQHGFVVIPKSVSQK 265
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTH 333
R+ N IFDF L+ +E+++++G D +
Sbjct: 266 RIVSNSKIFDFELSSEEMKELDGLDEY 292
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 165 bits (400), Expect = 4e-39
Identities = 93/270 (34%), Positives = 148/270 (54%), Gaps = 20/270 (7%)
Query: 74 SKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNT 133
S +++L + + AI +GYRH D A VY TE E+G A+K E + RE++F+TTK+
Sbjct: 39 SVNRELVEAIKTAIRLGYRHLDGAEVYGTEAELGVAIK----ESGIPREELFVTTKVITN 94
Query: 134 QHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGI 193
++ AI+ SL+KL L+Y+DLYL+H P ++ SD + + W +E Q+ G
Sbjct: 95 I---ADIPSAIDQSLRKLQLNYVDLYLIHSPF-----FAKSDGELQQAWAAMEKVQQAGK 146
Query: 194 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 253
K IG+SN+++ LE LK I P QIE H Q+E++ F + + + + Y P
Sbjct: 147 AKAIGVSNYHQSHLEATLKTAVIAPVINQIEHHPYLQQEELLRFQREKDIKIASYGPLTP 206
Query: 254 LVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENIN 313
++ G V DP +S +A KY T +++LRW I+R V + + RL+E +
Sbjct: 207 ILRAPGGPV------DPKVSELAAKYKVTEGEVLLRWSIDRGDVAVTTSSKESRLQEFLQ 260
Query: 314 IFDFTLTPDEVEKINGFDTHTRYTLPSFWQ 343
+ F LTP+EV +I+ Y +FW+
Sbjct: 261 VLTFQLTPEEVREISQLGQGRHYR--AFWR 288
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 164 bits (399), Expect = 5e-39
Identities = 97/275 (35%), Positives = 158/275 (57%), Gaps = 28/275 (10%)
Query: 73 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 132
K + Q V AI+ G+RHFDTA YE E+EIGEA++ +++ G + RE+IF+TTKLWN
Sbjct: 40 KLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWN 99
Query: 133 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG-----------LNADYSHS-DVDFME 180
T H +V + L+ LG YIDLYLMH+P+G ++ D + ++D+++
Sbjct: 100 THHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLD 159
Query: 181 TWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQS 240
TWR +E+ ++G+V+ IGLSNFN +Q++R+++ + KP Q+E+ +QK++V++C+
Sbjct: 160 TWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRY 219
Query: 241 EGVVVMG-YSPFGSLVARHGSTV--EGPKIDDPVLSSIAQK------YGKTTPQIVLRWQ 291
G ++ + + + +V G D + S+ A + +G I L
Sbjct: 220 NGNYCDSLFTSWSTKQKKSLPSVFLFGRCETDWLRSTSALQVKLVAIFGSIFISIRLNLN 279
Query: 292 IERKV-------VPIPKTVNPKRLEENINIFDFTL 319
I ++ VPIPK NP ++EN+NIFDF L
Sbjct: 280 INIRILEIDYGVVPIPKAANPIHIKENLNIFDFKL 314
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 164 bits (398), Expect = 7e-39
Identities = 94/279 (33%), Positives = 159/279 (56%), Gaps = 21/279 (7%)
Query: 79 LRDVVMRAI-DVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
L+ V AI D GYRH D A+ Y+ ++ IGEA+ +G VKRE+++IT+K+WNT+HR
Sbjct: 20 LKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKREEVWITSKVWNTKHRP 79
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA----DYSHSD---------VDFMETWRG 184
+ + + +LK+L L+Y+DL L+HW + +Y D +D +ETW+
Sbjct: 80 DLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDETGKIITENIDILETWKA 139
Query: 185 LEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSEG 242
+E+ +G+ K IG+SNF+ +QLER+ + +K P Q+E H+ Q+ M+++
Sbjct: 140 MEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESHMYLQQQPMLDYLTQRK 199
Query: 243 VVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRW--QIERKVVPIP 300
+ ++ Y+ G + P + DPVL+ +A++ GKT Q LR+ ++ V IP
Sbjct: 200 MYMISYTCLGRATLK--GPYGYPLLQDPVLNEVAKEIGKTPAQTNLRFLLKLSPYAVVIP 257
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
K++NP ++ NI++ DF LT ++ EK+ R+ P
Sbjct: 258 KSLNPANIKGNISL-DFDLTQEQFEKLRSRQCGWRFVNP 295
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 164 bits (398), Expect = 7e-39
Identities = 102/290 (35%), Positives = 153/290 (52%), Gaps = 24/290 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G + D Q + V + + G R DTA VY EQ++G +K + V RE+IF+ TK
Sbjct: 52 GTFQDPDSQ-EETVCQVLQRGMRLIDTARVYGVEQQVGRGIK----KSGVPREEIFLGTK 106
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS-----------HSDVDF 178
LW +V +A++DSL+ L Y+DL LMH+P H + F
Sbjct: 107 LWCNDFHPDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDRFPRDAEGRMIHGETTF 166
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFC 238
++TWR LE + G V+ IG+SNF+K ++E +L+E + P Q+EVH QK E+
Sbjct: 167 VDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQMEVHPYLQQKGFNEWL 226
Query: 239 QSEGVVVMGYSPFGSL---VARHGSTVEGPK----IDDPVLSSIAQKYGKTTPQIVLRWQ 291
+ +G+ V+ +SP G++ + G + E ID P+L I QKYGK+ Q+VL W
Sbjct: 227 REKGIHVVQFSPLGNMNDFYRQAGWSKEIAHMMRVIDQPILKEIGQKYGKSPVQVVLAWG 286
Query: 292 IERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSF 341
I IPKTV ++EEN+ DF L +++ +I D R+ PSF
Sbjct: 287 INSGRSVIPKTVIDWQIEENL-AADFELDAEDMARIATLDAKARFNDPSF 335
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 163 bits (397), Expect = 9e-39
Identities = 94/297 (31%), Positives = 165/297 (55%), Gaps = 22/297 (7%)
Query: 61 GQQCGLFQNGVVKSKD-KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV 119
GQ+ F G + + +++ +++ +A+DVGYRH DTA +YE EQ IG A+K EG
Sbjct: 15 GQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTIFGEGKY 74
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD----YSHSD 175
KREDIF+ TK + + + + L+KL +DY+DL L+H P+ +D ++H
Sbjct: 75 KREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAPSDDYQQWNHKP 132
Query: 176 VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMV 235
V + W E+ +G+ KG+G+SNFN Q + +L IKP QIE+H+ N QK +V
Sbjct: 133 VH--QIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIELHVFNQQKNLV 190
Query: 236 EFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
EF + + + +SP +A++ V+ + L+ IAQK + Q+++ + +
Sbjct: 191 EFLKKVNIYPVAFSP----MAKYNEVVK-----NETLNQIAQKQNASVAQVMIAFMYHQD 241
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR----YTLPSFWQNHPYY 348
VV IP+T +RL+ N + + ++++ + +++TR Y+ P+ ++ P+Y
Sbjct: 242 VVVIPRTAKIERLQHNFDAQKLQFSEEDIQTLRNLNSNTRVVNYYSYPALFKGIPFY 298
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 163 bits (397), Expect = 9e-39
Identities = 90/262 (34%), Positives = 139/262 (53%), Gaps = 17/262 (6%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G K +++ V AI+VGYRH DTAS+Y+ E+E+G AV + G V R+++FITTK
Sbjct: 28 GTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVADAITAGEVARDELFITTK 87
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
+WN H ++ +SL +LGLDYID ++HWP Y +E++ L Q
Sbjct: 88 VWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWPWPQKGLY-------VESFAALAKIQ 140
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+G ++ + ++NF + L ++ E I P Q+E+H Q E + GVV +S
Sbjct: 141 GLGQLQSVAVANFYPEVLREIVAETGIAPVLNQVELHPGFSQAEQRAVDRELGVVTEAWS 200
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P G G ++ ++ IAQ Y KT Q+ LRW + +PK+ NP+R
Sbjct: 201 PLG----------RGDSLNAEAITLIAQCYEKTPAQVTLRWIHQLGCSVVPKSANPQRQR 250
Query: 310 ENINIFDFTLTPDEVEKINGFD 331
EN++IFDF L +++ I D
Sbjct: 251 ENLDIFDFELNTEDMNSITSLD 272
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 163 bits (397), Expect = 9e-39
Identities = 105/333 (31%), Positives = 167/333 (50%), Gaps = 46/333 (13%)
Query: 22 EVPSLKMNNGRDMPAIGLGTYLGFDQAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRD 81
++P + +G MPAIG+GT+ G D A APG+ V S
Sbjct: 15 KIPQRTLASGARMPAIGMGTF-GSDHA----------APGE--------VAAS------- 48
Query: 82 VVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGV-VKREDIFITTKLWNTQHRRTEV 140
V A ++GYRHFD A+VY E+EIG + + ++RED++IT+KLWN +H +V
Sbjct: 49 -VYAAAELGYRHFDCAAVYSNEREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADV 107
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPI------GLNADYSHSD------VDFMETWRGLEDA 188
A SL+ LGLDY+DLYL+HWP G + D +FM+TWR LE
Sbjct: 108 IPAFEKSLRDLGLDYLDLYLIHWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETL 167
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
G+V+ IG SN +L+ +L++ ++P ++E+H Q + ++ + +V +GY
Sbjct: 168 HDRGLVRHIGTSNMTIAKLQLLLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGY 227
Query: 249 SPFGS--LVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
P GS R + + ++DPV+ IA +G + L+W ++R PIP + +
Sbjct: 228 CPLGSPGRPERDRTAEDTSPLEDPVIQRIAAAHGMHPAAVCLKWAVQRGQTPIPFSTKRR 287
Query: 307 RLEENI----NIFDFTLTPDEVEKINGFDTHTR 335
+ N+ ++ L+ E+ I D H R
Sbjct: 288 NIHANLAAAASVTTAPLSEQEMADIAATDRHCR 320
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 163 bits (397), Expect = 9e-39
Identities = 85/219 (38%), Positives = 135/219 (61%), Gaps = 14/219 (6%)
Query: 79 LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV-KREDIFITTKLWNTQHRR 137
++DVV+RAI+ GYRHFDTA+VY+TE +G+AV V G+V R++++IT+KLW
Sbjct: 32 VKDVVLRAIEAGYRHFDTAAVYQTEAILGDAVAEAVRAGLVASRDELYITSKLWVAHAHP 91
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGL-------NADYSHSDVDFME---TWRGLED 187
V ++ +L+K+ ++Y+DLYL+H+P+ + + YS D+ M+ W+ +E+
Sbjct: 92 GHVLPSLRRALRKMQMEYLDLYLIHFPVSMRLAEDPESMTYSKDDLVMMDMEGVWKEMEE 151
Query: 188 AQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
QR+G+ K IG+SNF+ ++LE +L TI P A Q+EVH Q ++ EFC+ +G+ +
Sbjct: 152 CQRLGLTKAIGVSNFSCKKLETLLSFATISPAANQVEVHPYCRQNKLREFCKEKGIQLCA 211
Query: 248 YSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQI 286
YSP G + +D P+L IA + GKT QI
Sbjct: 212 YSPLG---GKGTPWSNNAVMDCPLLKQIAMERGKTIAQI 247
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 163 bits (397), Expect = 9e-39
Identities = 99/274 (36%), Positives = 154/274 (56%), Gaps = 27/274 (9%)
Query: 70 GVVKSKDKQLRDVVMRAI-DVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
G KS +++ V A+ + GYRH DTA Y E +G +K +E+GV KREDIF+TT
Sbjct: 48 GTWKSTTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGIKRAMEKGV-KREDIFVTT 106
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS----------DVDF 178
K+W T H R E + ++ SL++LGLDY+D+ L+HWP+ LN + + D+D
Sbjct: 107 KIWVTYHDRVE--ENLDMSLERLGLDYVDMLLIHWPVPLNPNGNDPVYPLRPDGSRDIDE 164
Query: 179 M----ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEM 234
+TW+ +E + G K IG+SNF+ LE +LKE + P Q+E+H Q E+
Sbjct: 165 SGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAEVVPAVNQVELHPLLPQLEL 224
Query: 235 VEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIER 294
+EFC+ +V+ +SPFGS V GP + + ++ S+A KY + I+ + I
Sbjct: 225 MEFCKKNNIVMTAFSPFGS--------VGGPLLKNELVVSLADKYNTSPGGILTSYHIGN 276
Query: 295 KVVPIPKTVNPKRLEENINIFDFTLTPDEVEKIN 328
V IPK+V R+ EN TL+ ++++ +N
Sbjct: 277 GTVVIPKSVTNSRIVEN-GKSAVTLSQEDLKALN 309
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 163 bits (396), Expect = 1e-38
Identities = 86/262 (32%), Positives = 142/262 (54%), Gaps = 25/262 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV ++ + +VV A+ +GYR DTA +Y+ E+ +G+ G+ +IF+TTK
Sbjct: 28 GVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVGK--------GLEDHPEIFLTTK 79
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
LWN + +A +S + L +DLYL+HWP+ Y +ETW+ L + +
Sbjct: 80 LWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMPAQGQY-------VETWKALVELK 132
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+ G VK IG+SNF + LER++ + P QIE+H Q+ + EF + + +
Sbjct: 133 KSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELHPDFQQRALREFHEKHNIRTESWR 192
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P G +G + D + IA+K+ +T Q+V+RW ++ ++ IPK+VNPKRL
Sbjct: 193 PLG----------KGRVLSDERIGKIAEKHSRTPAQVVIRWHLQNGLIVIPKSVNPKRLA 242
Query: 310 ENINIFDFTLTPDEVEKINGFD 331
EN+++F F L D+++ I D
Sbjct: 243 ENLDVFGFVLDADDMQAIEQMD 264
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 163 bits (395), Expect = 2e-38
Identities = 85/280 (30%), Positives = 160/280 (57%), Gaps = 24/280 (8%)
Query: 60 PGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV 119
P CGL+ ++ ++D + ++ +A+ G+RHFDTA Y E +G A++ V
Sbjct: 15 PRPGCGLW---LIDNRD--VDSLIRQALKAGFRHFDTAQAYFNEDGVGRALRYTE----V 65
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFM 179
RE +FIT+K+ + N++L++LG++Y++L+L+HWPI Y +
Sbjct: 66 PREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAKNLY-------V 118
Query: 180 ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQ 239
ETW + + G+++ IG+SNF Q +ER++++ + P Q+E+H Q ++ ++
Sbjct: 119 ETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHH 178
Query: 240 SEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPI 299
G+ + YSPFGS +G+ V + + V+ +A+++ + QIVLRW +++ + P+
Sbjct: 179 EAGIAIQSYSPFGS----NGAAV----LRNAVVMVLARRHDHSPAQIVLRWHLQQGLTPL 230
Query: 300 PKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
P+T N R EN++++DF L+ +E++ + +T T T P
Sbjct: 231 PRTTNGARFSENVDVWDFELSEEEMKLLASLNTRTGNTQP 270
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 163 bits (395), Expect = 2e-38
Identities = 93/280 (33%), Positives = 151/280 (53%), Gaps = 36/280 (12%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G +SK+ + V+ A+ GYRH D A+VY E E+G+A+ ++ V R +IF+TTK
Sbjct: 25 GTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGKAI----QDSGVPRNEIFLTTK 80
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY--------------SHSD 175
LW T R + +A++ SL++LGLDY+ LYL+HWP+ L + D
Sbjct: 81 LWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVPLRTENIKDGNLFQFAEKPDGSKD 138
Query: 176 VD----FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQN 229
VD F++TW ++ G K IG+SNF+ L+ +L T K P Q+E H
Sbjct: 139 VDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLLAAPTTKVTPAVNQVEFHPLL 198
Query: 230 VQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLR 289
Q+E++++C +G+V+ YSP G P + DP + IA+ G +V+
Sbjct: 199 PQEELIQYCSEKGIVIEAYSPLGG--------ENAPILSDPTVQEIAKANGVEAGHVVIS 250
Query: 290 WQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKING 329
W +++ +V +PK+V P R+ N+ + TL+ +V K++G
Sbjct: 251 WAVQKGLVTLPKSVTPSRIVGNLKV--LTLSDSDVAKVDG 288
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 163 bits (395), Expect = 2e-38
Identities = 90/249 (36%), Positives = 138/249 (55%), Gaps = 20/249 (8%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
++ AID GYR DTA YE E E+G AV+ V R+++ + +K+ QH R E
Sbjct: 34 MVAAIDSGYRLLDTAVNYENESEVGRAVRASS----VDRDELIVASKIPGRQHGRAEAVD 89
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
+I SL +LGLD IDL L+HWP + S +++TWRG+ DA+ G+V+ IG+SNF
Sbjct: 90 SIRGSLDRLGLDVIDLQLIHWP-------NPSVGRWLDTWRGMIDAREAGLVRSIGVSNF 142
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
+ L+ ++ E + P Q+E+H Q + F G+ +SP +AR
Sbjct: 143 TEPMLKTLIDETGVTPAVNQVELHPYFPQAALRAFHDEHGIRTESWSP----LARRSEL- 197
Query: 263 EGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPD 322
+ + +L +A YG T Q+VLRW ++ PIPK+ +P R EN ++F F LT D
Sbjct: 198 ----LTEQLLQELAVVYGVTPTQVVLRWHVQLGSTPIPKSADPDRQRENADVFGFALTAD 253
Query: 323 EVEKINGFD 331
+V+ I+G +
Sbjct: 254 QVDAISGLE 262
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 162 bits (394), Expect = 2e-38
Identities = 87/267 (32%), Positives = 151/267 (56%), Gaps = 24/267 (8%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G++ LF GV + + DV + A+ GYR DTA +Y+ E+E+G AV+ + +K
Sbjct: 18 GRKMPLFGLGVFRL-ETGCEDVCLFALKNGYRMLDTADIYQNEKEVGSAVR----KSGLK 72
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 180
REDI++TTKL ++ + + +S+KKL + Y+DL+L+H P N +
Sbjct: 73 REDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTPRPGN---------IIA 123
Query: 181 TWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQS 240
+ L + G+++ +G+SNF LE + K G P QIE++ Q+E++++C
Sbjct: 124 AYDALLTLKEEGLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYCNK 183
Query: 241 EGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
G+ V GY+P G K D PVL ++++YGKT QI++RW ++++ + IP
Sbjct: 184 HGITVEGYAP----------VFRGCKFDHPVLVEMSERYGKTVAQIMIRWSVQKQYITIP 233
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKI 327
K+ NP+R+ EN +FDF ++ +++ +
Sbjct: 234 KSSNPERILENAQVFDFVISEKDMKNL 260
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 162 bits (394), Expect = 2e-38
Identities = 88/263 (33%), Positives = 150/263 (57%), Gaps = 24/263 (9%)
Query: 88 DVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDS 147
+ G RH DTA Y + IGE +K +G +KRED+FITTKLW T HR+ V ++++
Sbjct: 29 ECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKREDMFITTKLWCTHHRKDLVEPELHEN 88
Query: 148 LKKLGLDYIDLYLMHWPIGLNA---------------DYSHSDVDFMETWRGLEDAQRMG 192
L +L L Y+DL+L+H PI + + +D +ET+ +E+ Q+ G
Sbjct: 89 LAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPKDEKGKIQYEQIDILETYHAMEECQKKG 148
Query: 193 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
+ + IG+SNF+ +QLER+ IKP A Q+E ++ K ++ +C+S + +M ++ G
Sbjct: 149 LTRHIGVSNFSIEQLERIWFNCEIKPYANQVECNIYRQFKPLLSYCESHNIYLMAHTTIG 208
Query: 253 --SLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRW--QIERKVVPIPKTVNPKRL 308
L G+++ ++DPV+ +A + KT+ QI L++ Q + + IP ++NPK +
Sbjct: 209 HPPLKGPFGTSL----LEDPVVKQVASEAKKTSAQICLKFLQQKSKMYILIPMSMNPKNI 264
Query: 309 EENINIFDFTLTPDEVEKINGFD 331
+ N + DFTLT +++K+ D
Sbjct: 265 KSNYEL-DFTLTEQQMKKLEELD 286
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 162 bits (394), Expect = 2e-38
Identities = 90/259 (34%), Positives = 150/259 (57%), Gaps = 25/259 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G+ + D + +VV AI GYRH DTA +Y +E ++G+ +K ++E +VKRE++F+TTK
Sbjct: 19 GLGTASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGIKRAIDEELVKRENLFVTTK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD-----------------YS 172
+W T + R V+++++ SLK L LDY+DL L+HWP+ L AD YS
Sbjct: 79 VWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPVSLLADSDDPRAIYLVNTDGSVRYS 136
Query: 173 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQK 232
S D++ T++ +E+ + G K IG+SN ++ L+R+L + P Q E+H QK
Sbjct: 137 DSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQVKTVPAVNQFEIHPYLPQK 196
Query: 233 EMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQI 292
+ +EF + G++V +SP GS ST ++P+ IAQK+ +T +++ W +
Sbjct: 197 KEIEFNEKHGILVTAFSPLGS------STGALKLHENPIAVEIAQKHNTSTGSVLINWHV 250
Query: 293 ERKVVPIPKTVNPKRLEEN 311
+K +PKT + +R+ N
Sbjct: 251 SQKRAVLPKTRSIERVVAN 269
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 161 bits (392), Expect = 4e-38
Identities = 89/248 (35%), Positives = 135/248 (54%), Gaps = 22/248 (8%)
Query: 82 VVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVA 141
+V +A+++GYRH DTA +Y E+++G A++ VKR++IF+TTK+W Q ++
Sbjct: 33 LVEKALEIGYRHIDTAQIYGNERDVGAAIR----NSGVKRDEIFLTTKVWIDQFADGDLQ 88
Query: 142 QAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSN 201
++ SL+KLG+D +DL L+HWP +V ET + L + G + IGLSN
Sbjct: 89 RSAEKSLEKLGVDQVDLLLLHWP--------KPEVPLAETLKALNAVRAKGWTRAIGLSN 140
Query: 202 FNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGST 261
F QLE K Q+E H K + GV + +SP
Sbjct: 141 FPSAQLEEAAKLSEAPIATDQVEYHPYLSLKTLKAKADQLGVSITAWSPLA--------- 191
Query: 262 VEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTP 321
+G DPVL I + +GKT Q+ LRW I++ ++ IP+T NPKR+EEN +I DF L+
Sbjct: 192 -QGKVAQDPVLIEIGRAHGKTPGQVTLRWIIQQGIIAIPRTSNPKRIEENFDILDFELSE 250
Query: 322 DEVEKING 329
E+ +I+G
Sbjct: 251 KEMAQIHG 258
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 161 bits (392), Expect = 4e-38
Identities = 93/266 (34%), Positives = 143/266 (53%), Gaps = 15/266 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV++ D+ + VV A++ GYRH D A+ Y E +G A+ KRE +++TTK
Sbjct: 28 GVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALAASGYNKGAKRETLWVTTK 87
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
L ++Q +A ++SLK L LDY+D+Y++HWP D+ +D TW+ +
Sbjct: 88 LRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPTPF--DWRSTD-----TWKAFVKLR 140
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G+ + +G+ NF L+R+ +E P QIE+H Q+E+V FC+ G+ V YS
Sbjct: 141 DEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCKEHGIAVEAYS 200
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P +AR G D + IA + + Q++LRW IE + IPK+V+ R +
Sbjct: 201 P----MARGADLNAG----DGTIEKIAAAHEVSPAQVILRWHIENGTIIIPKSVHADRQK 252
Query: 310 ENINIFDFTLTPDEVEKINGFDTHTR 335
EN+N+F F LT DE I+ D TR
Sbjct: 253 ENLNLFGFALTADEHAAIDALDGPTR 278
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 161 bits (391), Expect = 5e-38
Identities = 99/286 (34%), Positives = 154/286 (53%), Gaps = 33/286 (11%)
Query: 60 PGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV 119
P G +Q +D +L D ++RAI VGYRH DTA+ Y E E+G+AV+ + GV
Sbjct: 17 PSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNEAEVGQAVR---QSGVA 73
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD--------- 170
R +IF+TTKL +V Q + +SL +LG+DYIDL+L+HWP G D
Sbjct: 74 -RSEIFVTTKL--RPGGVHDVVQELENSLNELGIDYIDLWLLHWPQGFTKDDGGFGTGES 130
Query: 171 -----YSHSDVDFMETWRGLEDA---QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQ 222
H F ETW +ED G VK IG+SNF+ + LE + K + P Q
Sbjct: 131 FGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIKNLEILAKTSKVTPAVNQ 190
Query: 223 IEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKT 282
IE H + E+V++C+ + + V YSP G ++ +++ +D L+ IA+K+ T
Sbjct: 191 IEAHPYLPEHELVKYCKHKSIHVTAYSPLG----QYNASIH----EDKDLNEIAKKHDVT 242
Query: 283 TPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKIN 328
+ L W ++R PK+ N KR+++NI + LT +E+++++
Sbjct: 243 AATVALSWAVQRGTSVAPKSTNEKRMKQNITL--IKLTDEEMKQVD 286
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 161 bits (391), Expect = 5e-38
Identities = 87/248 (35%), Positives = 139/248 (56%), Gaps = 19/248 (7%)
Query: 88 DVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDS 147
+ GYRH DTA+ Y E+E+G+ +K +E G+ R+D+F+T+K+W T V A+ ++
Sbjct: 48 EAGYRHVDTAAEYGVEKEVGKGLKAAMEAGI-DRKDLFVTSKIWCTNLAPERVRPALENT 106
Query: 148 LKKLGLDYIDLYLMHWPIGLNADYSHS--------DVDFMETWRGLEDAQRMGIVKGIGL 199
LK L LDYIDLY +HWP L D +H + D W+ +E+ + G+VK IG+
Sbjct: 107 LKDLQLDYIDLYHIHWPFRLK-DGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGV 165
Query: 200 SNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHG 259
N+ +L R+L+ I P Q+E+H ++ E C+ G+ V YSP GS
Sbjct: 166 CNYTVTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHVTAYSPLGS------ 219
Query: 260 STVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTL 319
E DPV+ +A K KT Q++++W ++R IPK+ +R++ENI +F + +
Sbjct: 220 --SEKNLAHDPVVEKVANKLNKTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEI 277
Query: 320 TPDEVEKI 327
P+E K+
Sbjct: 278 -PEEDFKV 284
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 161 bits (390), Expect = 6e-38
Identities = 94/269 (34%), Positives = 146/269 (54%), Gaps = 29/269 (10%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV +++ K+ D V +AID GYRH DTA Y E+ +G A++ V R +F+T+K
Sbjct: 23 GVYQARSKECEDAVKKAIDTGYRHVDTAQAYHNEENVGRAIR----NSGVPRPSVFLTSK 78
Query: 130 LW--NTQHRRTEVAQAINDSLKKL---GLD--YIDLYLMHWPIGLNADYSHSDVDFMETW 182
+T + TEV + SLKK+ G D YIDL L+H P G + W
Sbjct: 79 YMPSHTVYSPTEVLDVVRKSLKKVDRCGDDKPYIDLMLIHAPWG-------GEEGRKNNW 131
Query: 183 RGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEG 242
L AQ+ G VK IG+SNF L+ + P QIE+H Q+++V++C+ G
Sbjct: 132 EALTIAQKEGWVKDIGVSNFGIHHLKALPPP---VPAVNQIELHPFCQQRDIVKYCEEHG 188
Query: 243 VVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKT 302
+ + YSP +H D+ VL +A+KYGK Q++LRW +++ +P+PK+
Sbjct: 189 IAIEAYSPLVRANKKH--------YDNEVLVKVAKKYGKEVAQVLLRWSLQKGYIPLPKS 240
Query: 303 VNPKRLEENINIFDFTLTPDEVEKINGFD 331
V P R+E N +++DF L +++ +I+G D
Sbjct: 241 VTPSRIESNADLYDFKLDQEDMAEIDGLD 269
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 160 bits (389), Expect = 8e-38
Identities = 99/264 (37%), Positives = 145/264 (54%), Gaps = 20/264 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G K + + AI+VGYR FD+A +Y E E+G A+ V+ G+ KRE+ FI TK
Sbjct: 18 GTYSLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINAAVKGGI-KREEFFIQTK 76
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
L + ++I SLK LGLDYID L+H P YS S +R +E
Sbjct: 77 LLESSSEDL-AKKSIEKSLKTLGLDYIDSLLIHMP------YSQSKA----MYRAMESFY 125
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+ GI++ IG+SNF + +K + P Q E HL QK + E +S+ ++ +S
Sbjct: 126 KQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCETHLLLQQKPLREAMKSKKTLLQSWS 185
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
PF +A GS +E +P L SIAQKY KT Q+VLR+ IE+ + IPKT R++
Sbjct: 186 PF---IAGKGSILE-----NPTLKSIAQKYNKTPAQVVLRFLIEQGISVIPKTSKRARMQ 237
Query: 310 ENINIFDFTLTPDEVEKINGFDTH 333
EN+N+FDF+L+ + + + DT+
Sbjct: 238 ENLNVFDFSLSAQDTQILKELDTN 261
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 160 bits (389), Expect = 8e-38
Identities = 100/303 (33%), Positives = 159/303 (52%), Gaps = 26/303 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGV-VKREDIFITT 128
G +S Q+ D V A+ GYRH D A++Y+ ++E+ E +K ++ +KREDIFIT+
Sbjct: 21 GTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYKDVPGLKREDIFITS 80
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG---------LNADYS------- 172
KLWN+QH V +A+++ L +L LDY+DLYL+HWP+ L D S
Sbjct: 81 KLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELFPLVKDSSVEGGDVV 140
Query: 173 -HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQ 231
+ D+ ++TW+ + + + +G+SN LE ++ + P QIE H
Sbjct: 141 INDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAIINATGVVPAVNQIERHPVLQS 199
Query: 232 KEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKT-TP-QIVLR 289
E++E+CQ +G+ V YS FG+ V P++ + V S +++ G T TP Q++L
Sbjct: 200 NELIEYCQKKGIHVTAYSAFGNNGFGVPLLVTRPEVKE-VAESASKRLGTTVTPAQVILA 258
Query: 290 WQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGF-DTHTRYTLPSFWQNHPYY 348
W IPK+V P R+ EN + LTP+E+ K++ RY P + N P +
Sbjct: 259 WSQVGGHSVIPKSVTPSRIHENFK--EVELTPEEIAKVSELGKDRRRYNTP-YVANTPRW 315
Query: 349 PFD 351
D
Sbjct: 316 DID 318
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 159 bits (387), Expect = 1e-37
Identities = 95/266 (35%), Positives = 140/266 (52%), Gaps = 20/266 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + ++ + V+ AI+ GYR DTA VY E E G+ V + VV RE++F+TTK
Sbjct: 18 GVFQIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIANAVVAREELFLTTK 77
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
LW ++ AI+DSLKKLG DY DL L+H P G D ++ L +AQ
Sbjct: 78 LWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG----------DVYGAYKALAEAQ 127
Query: 190 RMGIVKGIGLSNFNKQ---QLERVLKEGTIK-PDAIQIEVHLQNVQKEMVEFCQSEGVVV 245
G VK IG+SNF + +V+K + P QIE H +K + GV +
Sbjct: 128 ADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQIDQIEFHPYYQEKVARQLHDKYGVQI 187
Query: 246 MGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNP 305
+ P G ++ + P L IA K+ K+ Q+VLRW ++ ++ + K+VNP
Sbjct: 188 EAWGPLGRTANKYDT------FHQPELVEIAAKHDKSVGQVVLRWIMQSNIITVAKSVNP 241
Query: 306 KRLEENINIFDFTLTPDEVEKINGFD 331
R+ ENI+IF+F L D+++KI D
Sbjct: 242 SRMAENIDIFNFELDDDDMKKIETLD 267
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 159 bits (387), Expect = 1e-37
Identities = 93/256 (36%), Positives = 141/256 (55%), Gaps = 24/256 (9%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+ V A+ +GYRH DTA Y+ E+ +G A+ G+ E I+IT+KLW + + +
Sbjct: 31 NAVKEALRLGYRHIDTAHAYQNERSVGRAIH---SSGIPISE-IWITSKLWPSDY--DDA 84
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLS 200
+QAI L+ L L IDL L+H +G ++ + W LE+A + G VK IG+S
Sbjct: 85 SQAIERMLELLNLKQIDLLLLHQQVG----------NYRKAWIALENAVKSGKVKSIGIS 134
Query: 201 NFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGS 260
NF+ ++L + IKP A+Q+E H + QKE+ EF + G + + P G HG
Sbjct: 135 NFDGERLVDLFNFADIKPSALQVETHPYHQQKELQEFLKPYGTKIESWYPLG-----HG- 188
Query: 261 TVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLT 320
+ +D+ L IAQKY KT QI+LRW I+ ++ P++ + L ENINIFDF L+
Sbjct: 189 --DQRLLDESRLKKIAQKYNKTVAQIILRWHIQEGIIVFPRSTRVEHLAENINIFDFELS 246
Query: 321 PDEVEKINGFDTHTRY 336
E+++I D Y
Sbjct: 247 CTEIKEIRKLDKKQPY 262
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 159 bits (387), Expect = 1e-37
Identities = 95/282 (33%), Positives = 154/282 (54%), Gaps = 35/282 (12%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+ V RA+ GYR D A +Y E E+GEA+ + G +KRED+F+T+KL+ T + ++
Sbjct: 37 EAVKRALSEGYRQIDCAHLYGNEVEVGEALA-EAFNGSLKREDVFLTSKLYCTMNSLNKI 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWP----IGLNADY-SHSDVDFME-------TWRGLEDA 188
++ SLK LG+ Y+DLYLMHWP G D S+S D + W+ +E
Sbjct: 96 ENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPSNSGNDHRQFLNRLKKAWKAMEGL 155
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
+G+V+ IG+SNF QQ++ +LK I P Q+++H Q E+V+FCQS+G+ V +
Sbjct: 156 IELGLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKLHPFWRQDELVKFCQSKGIHVSAH 215
Query: 249 SPFG----------------------SLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQI 286
+P G + R +V GP + V++ IA ++ KT Q+
Sbjct: 216 TPLGVPASGPGPSDSGSGGEDEPGTPRISFRRSRSVHGPMLKLSVVAEIADRHKKTPEQV 275
Query: 287 VLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKIN 328
+LRW ++R +P ++ R+ +NI+IF ++L+ DE +N
Sbjct: 276 ILRWGLQRGTSVLPCSLKADRIRKNIDIFSWSLSDDECNCLN 317
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 158 bits (383), Expect = 4e-37
Identities = 92/278 (33%), Positives = 150/278 (53%), Gaps = 24/278 (8%)
Query: 59 APGQQCGLFQNGVVKSKDKQ-LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG 117
A G+Q + G D+ + + A D GYR FDTA +Y E +G A++ + G
Sbjct: 13 ADGRQMPVMGFGTYLLNDQPTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAIQ---QLG 69
Query: 118 VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVD 177
+ RE +F+T+K+ + +A+ SLK+L DY+DL L+HWP+ H
Sbjct: 70 L-PREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPVR-----EH---- 119
Query: 178 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 237
F +TWR LE + G VK IG+SN+ LE + + P Q+E H Q+ + ++
Sbjct: 120 FFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHPYLNQQALADY 179
Query: 238 CQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVV 297
Q +V +SP G V +DDP+L+ +A + K+ Q++LRW+++ ++V
Sbjct: 180 DQEHDIVTEAWSPLGRRVV----------LDDPMLAKMAAHHNKSVAQVILRWELQHQLV 229
Query: 298 PIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR 335
IPK+ +P+R++EN NIFDF+L DE+ I+ + + R
Sbjct: 230 TIPKSTHPERIQENANIFDFSLDIDEMTMIDLLNKNER 267
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 158 bits (383), Expect = 4e-37
Identities = 91/249 (36%), Positives = 139/249 (55%), Gaps = 20/249 (8%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVK-MKVEEGVVKREDIFITTKLWNTQHRRTEVA 141
V +A+DVGYRH D A Y E E+G+A++ V R+D+FI TK+WN H +V
Sbjct: 44 VTKALDVGYRHLDCAWFYLNEDEVGDAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVK 103
Query: 142 QAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHS---DVDFM----------ETWRGLE 186
+ +S + L +DYIDL+L+HWPI NAD + D ++ TWR +E
Sbjct: 104 WSAKNSCENLKVDYIDLFLVHWPIAAEKNADRTVKIGPDGKYVINKALTENPEPTWRAME 163
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVM 246
+ GIVK IG+SN+ L+++L+ IKP QIE+H E+VEFC ++
Sbjct: 164 ELVDSGIVKAIGVSNWTIPGLKQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQNDILPE 223
Query: 247 GYSPFGSLVARHGSTVEGPKI-DDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNP 305
YSP GS ++ G ++ D+P L+++A + G + Q++L W ++R V +PK+ P
Sbjct: 224 AYSPLGS---QNQVPTTGERVRDNPTLNAVADRRGSSLAQVLLAWGLKRGYVVLPKSSTP 280
Query: 306 KRLEENINI 314
R+E N I
Sbjct: 281 SRIESNFII 289
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 157 bits (382), Expect = 6e-37
Identities = 94/277 (33%), Positives = 147/277 (53%), Gaps = 20/277 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV--EEGV----VKRED 123
G+ K + +++ ++ GYR DTAS+Y E+ IG+ + V +G+ +KRED
Sbjct: 31 GIGTFKLNDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGKKIKRED 90
Query: 124 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IGLNADYSHSDVDFMET 181
+FIT+K + +A SLKKL LDY+D YL+HWP GL+ S + + +T
Sbjct: 91 LFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGSDSGNSIQRAQT 150
Query: 182 WRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT--IKPDAIQIEVHLQNVQKEMVEFCQ 239
WR LE + V+ IG+SN+ L +L IKP Q+E H N QK+++EFC+
Sbjct: 151 WRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQKDLLEFCK 210
Query: 240 SEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPI 299
+ +++ Y GS G +++ + A+K G+T Q++LR+ +E I
Sbjct: 211 NNKIILESY----------GSLAGGRLLNNESVKEFAKKVGRTPSQLLLRYCLEHNCPVI 260
Query: 300 PKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRY 336
PKT N RL EN I DFTL+ D V ++ + R+
Sbjct: 261 PKTENVHRLIENQMILDFTLSDDIVNSLDKLNKDQRF 297
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 157 bits (382), Expect = 6e-37
Identities = 100/280 (35%), Positives = 153/280 (54%), Gaps = 33/280 (11%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G+ + + Q ++ + A+ GYRH DTA +Y TE+ +G A++ E + RE++FITTK
Sbjct: 25 GLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKSVGNAIR----ESGIPREELFITTK 80
Query: 130 L-WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----------NADYSHSDVD- 177
L WN H R VA++ SL+ LG +YIDLYL+H+P + N D S V+
Sbjct: 81 LPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHFPQRVFYDETTDFPRNPDGSIKVVNS 137
Query: 178 --FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMV 235
+ W +E G VK IG+SN++ + LE +LK + P Q+E+H Q +++
Sbjct: 138 PTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELLKTAKVVPAVNQVELHPFLAQSKLL 197
Query: 236 EFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+C+ +G+ V Y+P G TV + DP + +A KYG + QIVL W + R
Sbjct: 198 AYCKEKGIAVTAYTPTGY------QTV----LTDPTIVELAGKYGVSPAQIVLAWHLSRG 247
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR 335
V PK+ N R +EN+N+ F L P++V KI+ D R
Sbjct: 248 VAAAPKSANESRQKENLNL-PF-LQPEDVAKISALDRGQR 285
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 157 bits (382), Expect = 6e-37
Identities = 90/272 (33%), Positives = 152/272 (55%), Gaps = 22/272 (8%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G +C F G + D V A+ GYRH D+A +Y E + G A+ +EE K
Sbjct: 11 GLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEETGTK 70
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 180
REDI+ T+KL + ++ ++ +I+ S+K GL YIDL+L+H P G D +E
Sbjct: 71 REDIWFTSKLNDLSGYKSTLS-SIDASVKACGLGYIDLFLLHSPYG----------DRIE 119
Query: 181 TWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEGTIKPDAIQIEVHLQNVQKEMVEFCQ 239
+W+ LE G ++ IG+SNF ++ +L I P QIE+H Q+++V++C+
Sbjct: 120 SWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIELHPFCSQQKVVDYCE 179
Query: 240 SEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPI 299
S+G+ + Y+P V G K + L +IA KY K+ QI++R+ ++R + +
Sbjct: 180 SKGIQLAAYAPL----------VHGEKFGNKQLLAIASKYNKSEAQIMIRYCLQRGFIVL 229
Query: 300 PKTVNPKRLEENINIFDFTLTPDEVEKINGFD 331
PK+ P+R++EN ++FDF ++ +++EK+ D
Sbjct: 230 PKSSTPRRIKENGDVFDFEISKEDMEKLYNLD 261
>UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG07276.1 - Gibberella zeae PH-1
Length = 284
Score = 157 bits (381), Expect = 8e-37
Identities = 89/268 (33%), Positives = 153/268 (57%), Gaps = 28/268 (10%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G K + + V+ A+ GYRH D+A++Y E + EA+ E+ V RED+F+TTK
Sbjct: 26 GSYKIRGETCAAAVLAALPAGYRHIDSAALYRNEVRVREAI----EQSGVFREDLFLTTK 81
Query: 130 LWNTQHRRTEVAQAINDSLKKL----GLD-YIDLYLMHWPIGLNADYSHSDVDFMETWRG 184
+ + R+TE +A D ++ + G D Y+DL LMH P G + ++ HS W
Sbjct: 82 V-GSPRRKTEKTEAYEDVIEAVERIAGKDGYVDLLLMHVP-GPSREHRHS------LWEA 133
Query: 185 LEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI-QIEVHLQNVQKEMVEFCQSEGV 243
+E A+R + IG+SNF + L+ + + T P ++ QIE+H QKE+V++CQ +
Sbjct: 134 MERAKREARARNIGVSNFRVRHLDEMKEYATEWPPSVNQIELHPWCQQKEVVKYCQDNEI 193
Query: 244 VVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTV 303
++ YSP + G +++DP++ I+ K+ K+ Q+++R+ +++ VP+PK+
Sbjct: 194 IIEAYSPLAT----------GARLEDPLVEGISTKHDKSHAQVLIRYSLQKGWVPLPKSS 243
Query: 304 NPKRLEENINIFDFTLTPDEVEKINGFD 331
P R+ EN N+FDF L D++E ++ D
Sbjct: 244 RPDRISENFNVFDFVLDEDDMETLDDLD 271
>UniRef50_Q5C3P7 Cluster: SJCHGC05795 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC05795 protein - Schistosoma
japonicum (Blood fluke)
Length = 177
Score = 157 bits (381), Expect = 8e-37
Identities = 71/149 (47%), Positives = 102/149 (68%), Gaps = 1/149 (0%)
Query: 375 INRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIE 434
IN LPKEL++R+ SYLD+ +LC+C+QV K W A DGSNW+ I+LF+FQR V+ V+E
Sbjct: 30 INDSLPKELIIRVFSYLDITTLCKCSQVCKFWYECAFDGSNWKSINLFDFQRYVQPKVVE 89
Query: 435 NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCS 494
I+QR GFLR+L L+GC ++ D ++K + C IE L+L+ C+ +T+ TC LG+ CS
Sbjct: 90 KIAQRSRGFLRELRLKGCRNVTDEALKCFTELCHMIESLDLSGCQNLTNGTCDYLGKNCS 149
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLT 523
L ++L+SC V D L+ L+ C LT
Sbjct: 150 LLTTLSLESCSRVDDTGLEMLS-WCSNLT 177
Score = 41.5 bits (93), Expect = 0.061
Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 7/79 (8%)
Query: 496 LQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKG 555
L+++ L C +V+D +LK + C ++ +++S CQ++T + L + C L +
Sbjct: 99 LRELRLKGCRNVTDEALKCFTELCHMIESLDLSGCQNLTNGTCDYLGKNCSLLTTL---- 154
Query: 556 KPRESVPRLRIDDSGIESL 574
ES R+DD+G+E L
Sbjct: 155 -SLESCS--RVDDTGLEML 170
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 155 bits (376), Expect = 3e-36
Identities = 86/256 (33%), Positives = 139/256 (54%), Gaps = 21/256 (8%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQH 135
D + V AI+ GYR DTA Y+ E +G+ ++ + V R+++F+TTK+ H
Sbjct: 30 DDEAAKAVATAIETGYRLIDTAENYKNETGVGQGIR----DAGVARDEVFLTTKMNKQWH 85
Query: 136 RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVK 195
+A SL++LGLDYIDL+L+HWP N D ++E + GL G+V+
Sbjct: 86 SVDGARRACEASLERLGLDYIDLFLIHWP---NPDQG----TYVEAFEGLTRLLDAGLVR 138
Query: 196 GIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLV 255
IG SNF L + G + P QI++ +++ ++ ++G+V +SP G
Sbjct: 139 AIGTSNFLPHHLNDLFAAGFV-PHVNQIQLDPYHLRPDITAIHAAKGIVTESWSPIGRA- 196
Query: 256 ARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIF 315
G + DP ++ IA+ +GKT QIVLRWQ++ VP PK+ +P+R +N+++F
Sbjct: 197 --------GEMLADPAITRIAEAHGKTPAQIVLRWQVQSGFVPAPKSADPERQAQNLDVF 248
Query: 316 DFTLTPDEVEKINGFD 331
F LT ++ +NG D
Sbjct: 249 GFALTESDMAALNGLD 264
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 155 bits (376), Expect = 3e-36
Identities = 89/249 (35%), Positives = 138/249 (55%), Gaps = 21/249 (8%)
Query: 80 RDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTE 139
R+ V A+ +GYRH DTA Y E+++G + ++ V RED+F+TTKL +
Sbjct: 27 RETVETALGMGYRHIDTAQAYGNERQVG----LGMDAAAVDREDVFLTTKLDGSNRDERS 82
Query: 140 VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGL 199
V ++ +SL KLG DY+DL L+HWP N + S ET + D G+V+ IG+
Sbjct: 83 VRRSTRESLNKLGTDYLDLLLIHWP---NTPWMAS---LSETLGAMNDVVEEGLVRHIGV 136
Query: 200 SNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHG 259
SNF+ L+R + Q++ H Q++++++C+ V++ YSP +AR
Sbjct: 137 SNFSPSLLDRARDISSAPIFTDQVQYHPYWDQRKLLDYCRIHDVLLTAYSP----LAR-- 190
Query: 260 STVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERK-VVPIPKTVNPKRLEENINIFDFT 318
G +DDP L I KYGK+ Q+ LRW +++ V IPK + + LE N+ +FDF
Sbjct: 191 ----GGVLDDPALVQIGNKYGKSPAQVALRWLVQQDGVAAIPKASSREHLEANLAVFDFE 246
Query: 319 LTPDEVEKI 327
LT E+E+I
Sbjct: 247 LTDAEMERI 255
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 155 bits (376), Expect = 3e-36
Identities = 86/261 (32%), Positives = 149/261 (57%), Gaps = 22/261 (8%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE--GVVKREDIFITTKLWNTQH 135
Q ++V + GYRHFDTA +Y E+E+G+ + + E G KRE+IF TTKLWN+Q+
Sbjct: 28 QTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNEDPGNHKREEIFYTTKLWNSQN 87
Query: 136 RRTEVAQAINDSLKKL-GLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIV 194
AI L ++ GL YIDL L+H P+ +ETWR +++A G+V
Sbjct: 88 GYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL-------EGSKLRLETWRAMQEAVDEGLV 140
Query: 195 KGIGLSNFNKQQLERVLK--EGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
K IG+SN+ K+ ++ +L E KP QIE+ +++E+ ++C+S+G+VV ++P
Sbjct: 141 KSIGVSNYGKKHIDELLNWPELKHKPVVNQIEISPWIMRQELADYCKSKGLVVEAFAPL- 199
Query: 253 SLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENI 312
G K+ +P L + ++ + Q+++RW ++ +P+PKT KRLE N+
Sbjct: 200 ---------CHGYKMTNPDLLKVCKEVDRNPGQVLIRWSLQHGYLPLPKTKTVKRLEGNL 250
Query: 313 NIFDFTLTPDEVEKINGFDTH 333
++F L+ ++++ ++ D +
Sbjct: 251 AAYNFELSDEQMKFLDHPDAY 271
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 155 bits (375), Expect = 4e-36
Identities = 87/284 (30%), Positives = 149/284 (52%), Gaps = 14/284 (4%)
Query: 61 GQQCGLFQNGVVKSKD-KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV 119
G Q L G K +D +QL+ V A+ GYR FDTA+VY E +G+ +K + + +
Sbjct: 11 GTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLKELLPKYGL 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IGLNADYSHSDVD 177
RED+FI +KL + H + SL++L +YIDLYL+HWP GL+ + S
Sbjct: 71 IREDVFIISKLAPSDHG-LRAKEGCLRSLEQLDCEYIDLYLIHWPGMEGLDPEDSRHSEY 129
Query: 178 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 237
++W LE+ G K IG+SN+ + + +L + P +QIE + +Q+E+ +
Sbjct: 130 RAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAVLQIECQPKLIQRELRDL 189
Query: 238 CQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVV 297
C G+ YS G +G + +P + I + G+T Q++LRW +++ +
Sbjct: 190 CMETGIHFQAYSSLG----------KGALLREPEVMDIVRHCGRTPAQVLLRWALQQGIS 239
Query: 298 PIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSF 341
+P++ P R+ EN +FDF L ++++++ + TR+ F
Sbjct: 240 VLPRSSQPSRVLENAQVFDFKLNETDMKRLDDLNCGTRFCKRDF 283
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 155 bits (375), Expect = 4e-36
Identities = 100/317 (31%), Positives = 166/317 (52%), Gaps = 32/317 (10%)
Query: 25 SLKMNNGRDMPAIGLGTYLGFDQAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDVVM 84
+ K+N G ++P IGLGT+ + E + +A + ++ L V +
Sbjct: 13 TFKLNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLT---LGYVAL 69
Query: 85 RAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAI 144
+ + + D A +Y E E+G+ +K V R ++F+TTK+W T HR+ E +
Sbjct: 70 HPLYIPFLAKDAAWIYGNENEVGQGIKASG----VPRSELFVTTKIWCTYHRQPEAC--L 123
Query: 145 NDSLKKLGLDYIDLYLMHWP----------IGLNADYSHS-DVDFM--ETWRGLEDAQRM 191
++SL++LGLDY+DL L+HWP I LN D S + D D+ +TW +E
Sbjct: 124 DESLQRLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPAT 183
Query: 192 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 251
G K IG+SN++ L+++L + I P A Q+E+H Q E+V++C +G++ YSP
Sbjct: 184 GKTKAIGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPL 243
Query: 252 GSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
GS GP + D + SIA+ + Q+V+ W +R VV +PK+V P R+E N
Sbjct: 244 GS--------SGGPVLQDERVQSIAKAHKADPAQVVISWAAQRGVVALPKSVTPSRIETN 295
Query: 312 INIFDFTLTPDEVEKIN 328
+ L+ +E+ ++N
Sbjct: 296 GKL--IVLSDEEMLELN 310
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 154 bits (373), Expect = 7e-36
Identities = 92/270 (34%), Positives = 151/270 (55%), Gaps = 21/270 (7%)
Query: 68 QNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFIT 127
Q + +L D ++ + +G+RH DTA Y T++E+GEA+K V REDI++T
Sbjct: 31 QAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQKEVGEALKRTD----VPREDIWVT 86
Query: 128 TKL---WNTQHRRTEV-AQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWR 183
TK W + ++ + +I+ +L +LG+DY+DL+L+H P + +H + W
Sbjct: 87 TKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLFLIHSPF-FTTEQTHG-YTLEQAWE 144
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK---PDAIQIEVH--LQNVQKEMVEFC 238
L +A++ G V+ IG+SN LE++ P QIE H LQN K +V FC
Sbjct: 145 ALVEAKKAGKVREIGISNAAIPHLEKLFAASPSPEYYPVVNQIEFHPFLQNQSKNIVRFC 204
Query: 239 QSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVP 298
Q G++V +SP L + VE + + L +A+KY KT Q++LR+ ++R ++P
Sbjct: 205 QEHGILVEAFSPLAPL-----ARVETNALAE-TLKRLAEKYKKTEAQVLLRYTLQRGILP 258
Query: 299 IPKTVNPKRLEENINIFDFTLTPDEVEKIN 328
+ + RL+E++N+FDF LT +EV +IN
Sbjct: 259 VTTSSKESRLKESLNLFDFELTDEEVNEIN 288
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 153 bits (372), Expect = 1e-35
Identities = 88/254 (34%), Positives = 148/254 (58%), Gaps = 18/254 (7%)
Query: 80 RDVVMRAID----VGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQH 135
R+V+ R ID VG+R DTA VY E++IG A+K + + +KREDIFIT+KL + +
Sbjct: 47 REVIKRVIDESFAVGFRSIDTAVVYRNEEDIGLALKELLPKYNLKREDIFITSKLSPSDN 106
Query: 136 RRTE-VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVD---FMETWRGLEDAQRM 191
+ + +++ DSLK L Y+DLYL+HWP G + +S + + TW L + Q+
Sbjct: 107 GDPDKIRKSVEDSLKALDTSYLDLYLIHWP-GASRILENSPDNPKLRVTTWATLVELQQK 165
Query: 192 GIVKGIGLSNFNKQQLERVLKE-GTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 250
G+++ IG+SN+ LE +L+ +KPD Q+E H Q E++EFC +G+ V YS
Sbjct: 166 GLLRSIGVSNYTVGHLEHLLEHCSGVKPDVNQVECHPHFRQDELIEFCTKQGIHVQAYSS 225
Query: 251 FGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEE 310
G+ T ++DPV+ IA + + +++L+W ++R + IPK + +++
Sbjct: 226 LGT-----SDTTN--LLEDPVVKKIASELNVSPARVLLKWALQRGLGIIPKAIKSDHIKD 278
Query: 311 NINIFDFTLTPDEV 324
NI + DF ++ D++
Sbjct: 279 NIKL-DFEISKDQM 291
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 153 bits (371), Expect = 1e-35
Identities = 88/270 (32%), Positives = 150/270 (55%), Gaps = 18/270 (6%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G++ Q G + ++ VV +A+++GYR FDTA Y E +G+ + ++
Sbjct: 12 GEKIPQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIW----NSDIE 67
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---IGLNADYSHSDVD 177
R DIF+TTKL +AI+ +L K GL+YIDL L+H P I +N
Sbjct: 68 RSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTNDRHFKG 127
Query: 178 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEF 237
+E WR +E+A + G V+ IG+SNF ++ +E ++ GTI P QIEVH+ V E++++
Sbjct: 128 NLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEVHIGKVPVELMDY 187
Query: 238 CQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVV 297
C+ G+ + YSP HG + DD ++ + A+KY T Q++L + ++ +
Sbjct: 188 CKKLGIKIEAYSPLS-----HGKLLN----DDQII-AYAKKYNVTPAQLMLAFDMQLGCI 237
Query: 298 PIPKTVNPKRLEENINIFDFTLTPDEVEKI 327
IPK+ N ++EN+NI +F ++ +++ K+
Sbjct: 238 VIPKSDNVTEMKENLNI-NFKISDEDIAKL 266
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 153 bits (371), Expect = 1e-35
Identities = 81/265 (30%), Positives = 139/265 (52%), Gaps = 21/265 (7%)
Query: 80 RDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLW-------N 132
+ + AI GYRH DTAS Y+ E+ +G +K ++ + R+D+F+T KLW +
Sbjct: 64 KSTISAAIQAGYRHIDTASGYQNEKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGD 123
Query: 133 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMG 192
+ + + SL +LGLDY+DLYL+H P G D+ +E WR L + Q G
Sbjct: 124 APKTKAQTLDECDASLARLGLDYVDLYLIHAPYG-------GDMR-LEQWRALLELQANG 175
Query: 193 IVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS--- 249
+ IG+SNFN+ L + G PDA QIE+H + + +++ + + + YS
Sbjct: 176 KARSIGVSNFNESHLNEIKAAGLPMPDANQIELHPWSQKPDLLAYMDQHAIAPIAYSSLV 235
Query: 250 PFGSLVARHG---STVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
P + + G + + K +A+KYG + Q++LRW ++ +PK++NP
Sbjct: 236 PLSTWRTKEGQASAKTDEMKAAGTTFRDMAEKYGVSEAQLLLRWGVQNGYAVLPKSMNPD 295
Query: 307 RLEENINIFDFTLTPDEVEKINGFD 331
R+ +NI++F F++ ++ K+ D
Sbjct: 296 RMRQNIDLFSFSIDDTDMAKMATMD 320
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 153 bits (371), Expect = 1e-35
Identities = 86/278 (30%), Positives = 149/278 (53%), Gaps = 15/278 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G K + + + A+ GYR FDTA Y E+E+GEA+K+ + + + R D+F+T+K
Sbjct: 27 GTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPKHGLSRSDVFLTSK 86
Query: 130 LWNTQHRRTEVAQA-INDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME----TWRG 184
+ E + + +SL+ L DYID+YL+H+P ++D + DV+ E +
Sbjct: 87 FFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDSD--NDDVNNAEYRKIAYEV 144
Query: 185 LEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVV 244
LE+A+ G V+ IG+SN+ LE + + P A Q+E H + + ++C+ + +
Sbjct: 145 LEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLEYHPHFARIPLQKYCKEKNIF 204
Query: 245 VMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
+ F SL ARH E I+DPV+ +A+K+ + P ++L W + + V +PK+V
Sbjct: 205 ---FQAFSSL-ARH----EPKLIEDPVVVELAKKHNTSVPLVLLAWALRQNVGIVPKSVT 256
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW 342
P R+ EN + D LTP++++ + D Y + W
Sbjct: 257 PSRIVENFKVIDIALTPEDIQSLTALDRGQHYIRCTGW 294
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 153 bits (370), Expect = 2e-35
Identities = 84/266 (31%), Positives = 138/266 (51%), Gaps = 23/266 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + ++ + +V A++ GYRH DTA+ Y E +G A+ + REDIFITTK
Sbjct: 26 GVFQVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVGAAISASG----IPREDIFITTK 81
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
L N + +A +S K LG++++DLYL+HWP+ Y+ E W+ +E
Sbjct: 82 LRNGEQGNAH--EAFQNSRKALGVEFVDLYLIHWPVPSQGLYT-------EAWKAMEKLY 132
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
++ IG+SNF + L+ +L + P Q+E+H Q+E+ C+ G+ V YS
Sbjct: 133 ANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQVEIHPTFQQQELAAKCRELGIAVEAYS 192
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P G +G ++ + +A KY T QIVL W + + + IPK+ + KR+
Sbjct: 193 PLG----------QGADLNATAVKDLAGKYDATPAQIVLAWHLAQGTIVIPKSADSKRMR 242
Query: 310 ENINIFDFTLTPDEVEKINGFDTHTR 335
EN+ L+P E+ +I+ ++ R
Sbjct: 243 ENLGAVAVELSPAELSEISALESGAR 268
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 153 bits (370), Expect = 2e-35
Identities = 90/257 (35%), Positives = 142/257 (55%), Gaps = 19/257 (7%)
Query: 81 DVVMRAID-VGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTE 139
D V+ +I GYR DTA Y E+++G AVK V RE++F++TKLW E
Sbjct: 29 DAVLHSIKKCGYRLIDTAKRYGVEKQLGIAVK----NCSVPREEMFLSTKLWPVDCG-DE 83
Query: 140 VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME-TWRGLEDAQRMGIVKGIG 198
V A S +KL DY+D+Y++H P D+ + + E TWR +E V+ IG
Sbjct: 84 VYNAFQTSCEKLQTDYLDMYMIHMP--QLPDWIVNQKETKEKTWRQMELLYEDEHVRSIG 141
Query: 199 LSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARH 258
+SN++ + L+ +L+ +I P A Q+E+H Q ++ +C G++ MGY P
Sbjct: 142 VSNYSIEDLDELLEFASILPHANQVELHPWFHQADLKNYCDELGILTMGYCPLA------ 195
Query: 259 GSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFT 318
+G ++D L IA KY K+ QI LRW I++ V +PK+ + +RL+EN N+FDF
Sbjct: 196 ----KGKYLEDETLCKIASKYQKSPAQICLRWSIQQNVPTVPKSTDCRRLKENTNVFDFE 251
Query: 319 LTPDEVEKINGFDTHTR 335
L+ +++ +N F + R
Sbjct: 252 LSAEDMNTLNSFSSQNR 268
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 152 bits (369), Expect = 2e-35
Identities = 80/259 (30%), Positives = 133/259 (51%), Gaps = 7/259 (2%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
A+ GYRH DTA ++ E E+G+ +K V R++I++T KLWNT HR V +AI
Sbjct: 82 ALKGGYRHIDTALIWRNEDEVGKGIKASG----VSRDEIWVTGKLWNTDHRPELVRKAIE 137
Query: 146 DSLKKLGLDYIDLYLMHWPIGLNADYSHSD--VDFMETWRGLEDAQRMGIVKGIGLSNFN 203
S+ LG++Y+DLYL+H+P+ + D ++TW+ +E+ R G+ + IG SNF
Sbjct: 138 TSIANLGVEYLDLYLIHYPVAWVPETRDVDNNTSLIDTWKAMEELVRAGLTRNIGFSNFA 197
Query: 204 KQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVE 263
+ + ++LK +I+P A + E H Q+ V+F + E + V+ SP + +G
Sbjct: 198 PKDINKILKIASIQPYAHEFETHPYLQQQSFVDFHKKENIKVIAASPLANTNPTYGDKYP 257
Query: 264 GPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDE 323
+ D +A+ T Q +L W +R + I K+ + + EN+ T E
Sbjct: 258 S-ILHDEFWVKLAEDKNATVAQTILAWGQQRGTIVISKSTHSNHIAENLCSQGIEFTKSE 316
Query: 324 VEKINGFDTHTRYTLPSFW 342
+E++ D R P W
Sbjct: 317 LEEVAKQDKKLRLLNPIHW 335
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 152 bits (369), Expect = 2e-35
Identities = 85/250 (34%), Positives = 132/250 (52%), Gaps = 22/250 (8%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
+ V AI GYRH DTA Y E+ +G + GV R+++FITTK+W
Sbjct: 27 EAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGI---AASGV-DRKELFITTKIWVENVSY 82
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGI 197
V + + SLK+LGLDYIDL L+H P D W +E+ Q G +K I
Sbjct: 83 KGVMSSFDRSLKRLGLDYIDLLLIHQPYN----------DVYGAWMAMEELQAQGKIKAI 132
Query: 198 GLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVAR 257
G+SNF ++ + I P QIE++ Q + +E + EGV V ++PF
Sbjct: 133 GVSNFGVDRVVDLAAFNDITPQVNQIEINPFQQQSKNIEALRKEGVAVEAWAPFAE---- 188
Query: 258 HGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDF 317
+ +P+L+ IA+KYGK+ Q++LRW IE+ ++ + K+V P+R+ +N+ +FDF
Sbjct: 189 ----GKNDIFTNPILTKIAEKYGKSVAQVILRWLIEQDIIVLAKSVKPERMAQNLAVFDF 244
Query: 318 TLTPDEVEKI 327
L+ ++ I
Sbjct: 245 ELSEEDKSAI 254
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 152 bits (369), Expect = 2e-35
Identities = 91/273 (33%), Positives = 144/273 (52%), Gaps = 22/273 (8%)
Query: 55 LSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 114
L EA G + G + + VV +A+ +GYRH DTA VY+ E+E+G+ V+
Sbjct: 2 LFVEANGARIPAIGLGTWELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDGVRASG 61
Query: 115 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 174
V+R+D+F+TTK+W ++ +++ +SL +L L +DL L+HWP +S
Sbjct: 62 ----VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWP--------NS 109
Query: 175 DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEM 234
V ET L A++MG+ + IG+SNF +E+ + Q+E H Q ++
Sbjct: 110 HVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPYLDQAKV 169
Query: 235 VEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIER 294
C G+ ++ YSP +AR G D L+ I + + KT Q+ LRW +++
Sbjct: 170 RAACDQHGLALVAYSP----IAR------GRIKTDQTLAGIGRAHRKTPAQVCLRWLVQQ 219
Query: 295 KVVPIPKTVNPKRLEENINIFDFTLTPDEVEKI 327
V IP+T +RL ENI IFDF L+ DE+ +I
Sbjct: 220 NVAAIPRTSRIERLSENIEIFDFELSDDEMARI 252
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 152 bits (368), Expect = 3e-35
Identities = 92/261 (35%), Positives = 137/261 (52%), Gaps = 25/261 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G ++ + + V A+D GY H DTA YE E +G A+ E+ V REDIF+TTK
Sbjct: 26 GTYRTGGYKCYNAVKNALDCGYTHIDTAMAYENEAAVGRAI----EQSSVDREDIFLTTK 81
Query: 130 L--WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLED 187
+ + + +A L++LG +Y+DL L+HW L D ET+ L
Sbjct: 82 IKGYPEMVEYERLIEAAKGCLERLGTEYLDLLLVHWWNPL--------ADMEETFNALNT 133
Query: 188 AQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+V IG+SNF+ ++L++ ++ QIE H +E+V FCQ V V
Sbjct: 134 LVDDGLVGQIGVSNFSIKELKQAMRLSDAPIATNQIEYHPYWGDEELVRFCQDNDVTVTA 193
Query: 248 YSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERK-VVPIPKTVNPK 306
YSP EG ++D VL SI +YGK+ Q+ +RW I+++ VV IPK PK
Sbjct: 194 YSPL----------AEGRAVEDDVLRSIGDRYGKSAAQVSIRWLIQQENVVTIPKAATPK 243
Query: 307 RLEENINIFDFTLTPDEVEKI 327
+E NI++FDF LT ++ +I
Sbjct: 244 HIEANIDVFDFELTDRDMRRI 264
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 151 bits (367), Expect = 4e-35
Identities = 87/277 (31%), Positives = 153/277 (55%), Gaps = 23/277 (8%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G Q + G ++ ++ + A+++G R FDTAS+Y E+E+GE ++ E +
Sbjct: 42 GYQIPIIGLGTTSLHNQTCKNAIKAALEIGIRLFDTASLYGNEKEVGETIR----ESNIN 97
Query: 121 REDIFITTKLW-NTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFM 179
R +IF+ TKL+ Q E +AI ++L KL DYID+ L+H P +DV
Sbjct: 98 RNEIFVITKLYPGAQFANPE--KAIEEALNKLNTDYIDMMLLHHP-------GENDV--- 145
Query: 180 ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQ 239
+ ++ +E G +K +GLSN+ +++ L + IKP IQ E+H+ +KE+V +
Sbjct: 146 KAYKAIEKYIEKGKIKSVGLSNWYIKEINSFLPQINIKPSLIQNEIHIYYQEKEVVPYMH 205
Query: 240 SEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPI 299
+ + + + PFG G T +++P + SIA+ + KT+ QI+ RW ++R ++ I
Sbjct: 206 NLNIAMQAWYPFGG----RGHTFS--VLNNPTIVSIAKDHNKTSAQIISRWLLQRGIITI 259
Query: 300 PKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRY 336
+ NP ++ENI++FDF L+ E+E I D + ++
Sbjct: 260 VGSSNPIHIKENISVFDFELSNQEMELIASLDKNEKH 296
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 151 bits (367), Expect = 4e-35
Identities = 89/262 (33%), Positives = 145/262 (55%), Gaps = 22/262 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G + D + V A VGYRH DTA Y E+ +GEAV+ + +KRE++FIT+K
Sbjct: 29 GTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVR----KSKIKREELFITSK 84
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA----DYSHSDVDFMETWRGL 185
+ + +I+ SLK + LD+IDL L+H P N+ DY +V E + L
Sbjct: 85 IRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNSFRKGDYFKENV---EVYNAL 141
Query: 186 EDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVV 245
EDAQ+ G V+ IG+SNF ++ LE +LK KP A QI H+ N ++++C+ + ++
Sbjct: 142 EDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQILCHIGNTPFTLLDYCKKQNILA 201
Query: 246 MGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNP 305
YSP HG ++ P++ + +A+KY + QI +R+ +E +V +PK+ P
Sbjct: 202 EAYSPIA-----HGELLKDPRVIE-----LAKKYNVSPAQICIRYTLELGLVSLPKSKTP 251
Query: 306 KRLEENINIFDFTLTPDEVEKI 327
K + EN + DFT + +++ +
Sbjct: 252 KYIAENAQV-DFTFSKADLQTL 272
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 151 bits (367), Expect = 4e-35
Identities = 81/261 (31%), Positives = 144/261 (55%), Gaps = 23/261 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G + + + R AI+ GYRH D A++Y+ E+++GE +K + + R+++F+TTK
Sbjct: 17 GTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEGIK----DSGIPRDELFVTTK 72
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
+WN ++ ++A+++SL +LGLDY++L L+HWPI +D+ + L + +
Sbjct: 73 IWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI--------NDMPIADQVGPLAEIK 124
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
R G K IG+SN+N+ Q + AIQ E H Q +++ + ++ YS
Sbjct: 125 RSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDPILKTARGFDMMFTSYS 184
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIER-KVVPIPKTVNPKRL 308
P G G + +P + +A+++GKT QI+LRW +++ V IPK + +
Sbjct: 185 PLG----------RGEAMSNPAIERLAEQHGKTPAQIILRWHLQQANVAAIPKATSKAHI 234
Query: 309 EENINIFDFTLTPDEVEKING 329
E+N +IFDF L+ +++ I G
Sbjct: 235 EQNFDIFDFELSATDMKTIYG 255
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 151 bits (366), Expect = 5e-35
Identities = 88/275 (32%), Positives = 135/275 (49%), Gaps = 25/275 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G + K + V A+DVGYRH DTA YE E E+G+A+ + R ++F+TTK
Sbjct: 17 GTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISASK----ISRGELFVTTK 72
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
+W + ++ +SL +L DY+DL L+HWP N V E + L+ +
Sbjct: 73 VWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWPSPDNK------VSMAEYLKELKACK 126
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI---QIEVHLQNVQKEMVEFCQSEGVVVM 246
G+ + IG+SNF + QL+ L + D I QIEVH KE+V +CQ + V
Sbjct: 127 ERGLTRHIGVSNFTQSQLDEALS--ILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVT 184
Query: 247 GYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
Y P G G +++ +L+ IA + T + L W +K+V IP + N
Sbjct: 185 AYMPLGV----------GKVMENDILNDIASAHDTTPSAVALAWLSHKKIVAIPSSTNVN 234
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSF 341
+ +N+ LT +E+EKI+G + R P F
Sbjct: 235 HMRDNLTAKQMMLTAEEIEKIDGIEPQERIVDPDF 269
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 151 bits (365), Expect = 7e-35
Identities = 85/249 (34%), Positives = 132/249 (53%), Gaps = 22/249 (8%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V AI GYRH DTA Y E+ +G + GV R+++FITTK+W V
Sbjct: 32 VKDAIKAGYRHIDTAQSYMNEEAVGRGI---AASGV-DRKELFITTKIWVENVSYKGVMS 87
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
+ + SLK+LGLDY+DL L+H P D W +E+ Q G ++ IG+SNF
Sbjct: 88 SFDRSLKRLGLDYVDLLLIHQPFN----------DVYGAWIAMEELQASGKIRAIGVSNF 137
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
+ ++ + + P QIEV+ Q + + EGV + ++PF
Sbjct: 138 SPDRVIDLAAFNEVTPQVNQIEVNPFQQQTANLAILRKEGVAIEAWAPFAE--------G 189
Query: 263 EGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPD 322
+ ++PVL+ I KYGK+ Q++LRW +E+ ++ + K+V P+R+ +N+ IFDF LT
Sbjct: 190 KNDIFNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLAIFDFELTEA 249
Query: 323 EVEKINGFD 331
+ E+I G D
Sbjct: 250 DKEEIAGLD 258
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 150 bits (364), Expect = 9e-35
Identities = 99/290 (34%), Positives = 154/290 (53%), Gaps = 24/290 (8%)
Query: 70 GVVKS-KDKQLRDVVMRAI-DVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFIT 127
G KS + + L + + AI + GY H D A YE E +G+A++ + G+ KRE+I+IT
Sbjct: 10 GTWKSPRSEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQCWDSGI-KRENIWIT 68
Query: 128 TKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-----GLNADYSHSD------- 175
+KLWNT HR V +A +LK L LDY+DLYLMH+P G+ + D
Sbjct: 69 SKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLNPLDEKGNTIF 128
Query: 176 ---VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV-LKEGTIKPDAIQIEVHLQNVQ 231
V ++TW+ +E G+VK IG+SN+ QLER+ + P Q+E +L Q
Sbjct: 129 DDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTNQVEFNLYMQQ 188
Query: 232 KEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRW- 290
+ E+ EG++V GYS G+ E + D L+ IA + GK+ ++ L++
Sbjct: 189 GPLREYMHKEGIIVTGYSTLGT--PDWAKPDEPVVLKDEELNKIAAETGKSVGEVELKFL 246
Query: 291 -QIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
IE + K+V P+R+ +N N DF LT D+++++ + RY P
Sbjct: 247 LTIEPGASLLAKSVTPERIYKN-NHLDFELTKDQIQRLRNRERFYRYVDP 295
>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
clavatus
Length = 283
Score = 150 bits (364), Expect = 9e-35
Identities = 85/265 (32%), Positives = 142/265 (53%), Gaps = 24/265 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV +S +Q + A+ GYR+ DTA Y EQE+GEA++ + R D+F+TTK
Sbjct: 26 GVYRSPTRQCVQSCLTALQAGYRNIDTAQFYANEQEVGEALRTSG----IPRSDVFVTTK 81
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLD--YIDLYLMHWPIGLNADYSHSDVDFMETWRGLED 187
+ + + + +S++K+G + Y+DL+L+H S E W+ LE
Sbjct: 82 ILSPAGSPEATYKKLLESVEKIGGENGYVDLFLIH-------SSSSGSAGRKELWQALEK 134
Query: 188 AQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI-QIEVHLQNVQKEMVEFCQSEGVVVM 246
G K IG+SNF + +E + + P + QIE+H Q+ + +C+ G+VV
Sbjct: 135 LLEEGKTKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYCKRNGIVVE 194
Query: 247 GYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YSP V K +DP L +A+KYGKTT Q+++R+ +++ VP+PK+ P+
Sbjct: 195 AYSPL----------VRNYKANDPTLVDLAKKYGKTTAQVLIRYALQKHWVPLPKSDTPE 244
Query: 307 RLEENINIFDFTLTPDEVEKINGFD 331
R+E N +FDF ++ +++ +N D
Sbjct: 245 RIEANTKVFDFEISEEDMAVLNALD 269
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 150 bits (363), Expect = 1e-34
Identities = 89/246 (36%), Positives = 131/246 (53%), Gaps = 20/246 (8%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
+ AID GYR DTA YE E +GEAV+ RE + IT+KL H +
Sbjct: 35 INNAIDHGYRLIDTAYNYENEGTVGEAVR----RSSTPREQLLITSKLPGRYHHYDKAVT 90
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
I +SL + LDY DLYL+HWP + D+ ++E W+ L +A+R G ++ IG+ NF
Sbjct: 91 TIQESLYRANLDYYDLYLIHWPNPIQ------DI-YVEAWQALIEAKRRGYIRSIGVCNF 143
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
+ LER+ +E P QIE+H Q++ ++ Q + +SP +AR
Sbjct: 144 LPEHLERLKQETGELPTINQIELHPFFNQEDQRKWHQEHQIATESWSP----LARTNDV- 198
Query: 263 EGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPD 322
+D PVL +A + +T QI+LRW + + IPK+ P R ENI+IFDF L+ +
Sbjct: 199 ----LDHPVLQKLASNHNRTVSQIILRWHYQLDAIAIPKSATPSRQLENISIFDFELSDE 254
Query: 323 EVEKIN 328
E+ IN
Sbjct: 255 EMSIIN 260
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 149 bits (362), Expect = 2e-34
Identities = 83/255 (32%), Positives = 141/255 (55%), Gaps = 21/255 (8%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+ V AI++GYR D A +Y E +GE ++ + R+++F+TTK+WN + +
Sbjct: 32 ETVRSAIEIGYRMIDGAYLYMNEAGLGEGLRASG----LPRDEVFVTTKVWNNEQGAAKA 87
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLS 200
++ SLK +G++ +DL L+HWP+ D+ ++ETW+ +D + G+++ IG S
Sbjct: 88 RASVERSLKTIGVEQLDLVLIHWPV------PSQDL-YLETWKAFQDMRDEGLMRSIGTS 140
Query: 201 NFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGS 260
NFN LER++ E P QIE++ Q EM ++ GVV ++P G+ AR
Sbjct: 141 NFNADHLERIIAETGEAPVLNQIELNPMLQQPEMRAVHKAHGVVTQAWTPLGN--ARSFE 198
Query: 261 TVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLT 320
+P+ ++A + GK+ Q++LRW ++ IP++V R EN+++FDFTLT
Sbjct: 199 A-------EPITKAVA-RTGKSPVQVILRWHVQLGNAVIPRSVKAHRQAENLDVFDFTLT 250
Query: 321 PDEVEKINGFDTHTR 335
E+ +I D R
Sbjct: 251 EAEMSEIATLDMGLR 265
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 149 bits (361), Expect = 2e-34
Identities = 87/268 (32%), Positives = 136/268 (50%), Gaps = 30/268 (11%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVE-----------EGV 118
G+ K +V A++ GYRHFDTA++Y E +G+A+ E
Sbjct: 21 GLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGALAGFAGGGPAGGSGEAA 80
Query: 119 --VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDV 176
+ RED+F+TTK+WN H +A + S+ LG++Y+DLYL+HWP
Sbjct: 81 PSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCARRG------- 133
Query: 177 DFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVE 236
F E++R +E R G ++ IG+SNF LE +L+ + P QIE+H Q E+ +
Sbjct: 134 LFTESYRAMETLYREGRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQ 193
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKV 296
G+ +SP G G + DPV+ +A + ++ QI+LRW ++
Sbjct: 194 LHDRLGIRTEAWSPLG----------RGQVLADPVVLELAAAHRRSAAQIILRWHVQLGN 243
Query: 297 VPIPKTVNPKRLEENINIFDFTLTPDEV 324
V IPK + R+ EN+++F FTL P E+
Sbjct: 244 VVIPKASSYARIRENLDVFGFTLDPAEM 271
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 149 bits (361), Expect = 2e-34
Identities = 92/258 (35%), Positives = 138/258 (53%), Gaps = 13/258 (5%)
Query: 90 GYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRT-EVAQAINDSL 148
G H D A Y T E+ +A+K E R +IFIT K ++TQ + T + + +N L
Sbjct: 54 GIIHIDAAECYGTYPELAKALK----ESSKPRSEIFITDK-YSTQTKFTNDPIEGLNTGL 108
Query: 149 KKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 208
K LGLDY+DLYL+H P + ++ S + + W+ +E + G K IG+SNF+ + +E
Sbjct: 109 KTLGLDYVDLYLIHSPF-FDPEFKGS-LTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIE 166
Query: 209 RVLKEGTIKPDAIQIEVH--LQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPK 266
+LK IKP QIE + LQN +V +CQ + + YSP G L R ++ E P
Sbjct: 167 EILKIAGIKPQVNQIEFNAFLQNQTPGIVNYCQKNNIQLEAYSPLGPLQKRPENSNELPF 226
Query: 267 IDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEK 326
+ + +A KYGKT QI+L W R ++PI + +R+ + NIF F LT DEV+
Sbjct: 227 YN--YIDELASKYGKTDSQILLNWVYNRGILPITTSSKTQRIIDAQNIFSFNLTKDEVDT 284
Query: 327 INGFDTHTRYTLPSFWQN 344
+ + L +W N
Sbjct: 285 LTKLGLE-QPALRIYWTN 301
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 149 bits (360), Expect = 3e-34
Identities = 83/249 (33%), Positives = 136/249 (54%), Gaps = 21/249 (8%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V A+ GYRH DTA Y+ E +G+A++ + + RE IF+TTKL
Sbjct: 36 VRAALAAGYRHIDTALAYQNEASVGQAIR----DSGIPREQIFVTTKLPAETKSYQGALN 91
Query: 143 AINDSLKKLGLDYIDLYLMH--WPIG-LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGL 199
+ SLK LGLDY+DLYL+H WP G + Y +++D W+ +E + G K IG+
Sbjct: 92 DFDRSLKNLGLDYVDLYLVHAPWPWGQVGRVYDEANLD---VWQAMEAIYQSGRAKAIGV 148
Query: 200 SNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHG 259
SNF + L+ +L + TI P QI+ +L + ++ +F + ++V YSP +
Sbjct: 149 SNFAVRDLKNILNQATIPPMVNQIQYYLGFTEPKITKFSEEHAMLVEAYSPLAT------ 202
Query: 260 STVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTL 319
G +D+P + + A KYG + Q+ LR+ ++ V+P+PK VNP +E N + DF +
Sbjct: 203 ----GGVLDNPQVQAYADKYGVSVAQLALRFVLQNGVLPLPKAVNPAHIEANTQL-DFAI 257
Query: 320 TPDEVEKIN 328
+ +++ +N
Sbjct: 258 SVADMQALN 266
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 149 bits (360), Expect = 3e-34
Identities = 94/300 (31%), Positives = 151/300 (50%), Gaps = 41/300 (13%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G +S + VV ++ GYRH DTA Y ++E+G+ +K + G+ +R D+F+T+K
Sbjct: 30 GTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAGL-ERRDLFVTSK 88
Query: 130 LWNT----------------------QHRRTE-----VAQAINDSLKKLGLDYIDLYLMH 162
LW T R TE V A+ ++LK+L L+Y+DLYL+H
Sbjct: 89 LWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPALQNTLKELQLEYLDLYLIH 148
Query: 163 WPIGLNADYSHS-------DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 215
WPI L S D D WR +E+ + +V+ IG+ NF +L ++L
Sbjct: 149 WPIRLREGASKPPKAGDVLDFDMEGVWREMENLSKDSLVRNIGVCNFTVTKLNKLLGFAE 208
Query: 216 IKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSI 275
+ P Q+E+H ++EFC+ + V YSP GS + G I D + I
Sbjct: 209 LIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYSPLGS---QEGGR---DLIHDQTVDRI 262
Query: 276 AQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR 335
A+K KT QI+++W ++R IPK++NP+R++ENI +FD+ + + + +N R
Sbjct: 263 AKKLNKTPGQILVKWGLQRGTSVIPKSLNPERIKENIKVFDWVIPEQDFQALNSITDQKR 322
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 148 bits (358), Expect = 5e-34
Identities = 86/265 (32%), Positives = 142/265 (53%), Gaps = 24/265 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV +S Q +RA++ GYRH DTA Y E+E+GEA++ + + R D+F+TTK
Sbjct: 26 GVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEALR----KCGIPRSDVFVTTK 81
Query: 130 LWNTQHRRTEVAQAINDSLKKLGL--DYIDLYLMHWPIGLNADYSHSDVDFMETWRGLED 187
+ + Q + +S++K+G Y+DL+L+H S E W+ LE
Sbjct: 82 ILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIH-------SSSSGSAGRKELWQALER 134
Query: 188 AQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI-QIEVHLQNVQKEMVEFCQSEGVVVM 246
G + IG+SNF + +E + + P + QIE+H Q+ + +C+ G+VV
Sbjct: 135 LLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIEAYCKRNGIVVE 194
Query: 247 GYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YSP V K +DP L +A+KY +TT QI++R+ +++ VP+PK+ P+
Sbjct: 195 AYSPL----------VRNYKANDPTLVDVAKKYERTTAQILIRYALQKGWVPLPKSDTPE 244
Query: 307 RLEENINIFDFTLTPDEVEKINGFD 331
R+ N N+FDF + +++ +NG D
Sbjct: 245 RIVANANVFDFEIGEEDLAVLNGLD 269
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 147 bits (357), Expect = 6e-34
Identities = 92/289 (31%), Positives = 143/289 (49%), Gaps = 25/289 (8%)
Query: 56 SFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVE 115
S +AP + G + KD D V+ A++ G RH DTA +Y EQ +G+A+
Sbjct: 9 SNQAPLTAMPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINTSG- 67
Query: 116 EGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSD 175
+ RE++FITTK+W + ++ DSL L Y+DL L+HWP LN+D S
Sbjct: 68 ---IPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWP--LNSD-EPSM 121
Query: 176 VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAIQIEVHLQNVQK 232
V+++ + + D G+ + IG+SNF QL + +L EG I + Q+EVH + +
Sbjct: 122 VEYLSELKAVLD---KGLTRRIGVSNFTNAQLAQAIAILGEGVIYTN--QVEVHPYLINR 176
Query: 233 EMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQI 292
++ +FC+ V+V GY PF G + D + ++A + T QIVL W
Sbjct: 177 KVTDFCRQHNVLVTGYMPF----------AYGAVLQDETIVNLASVHQATPAQIVLAWLR 226
Query: 293 ERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSF 341
+ IP + + N+ LTP E+E+IN D + R P F
Sbjct: 227 QLGFATIPSSTKRDNVRSNLAAASINLTPAEIEQINQLDRNHRVANPDF 275
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 147 bits (356), Expect = 8e-34
Identities = 81/267 (30%), Positives = 142/267 (53%), Gaps = 24/267 (8%)
Query: 70 GVVKSKDKQ-LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
GV + +++ + V +AI+VGYR FDTA+VY E +G+A+ + V RE++FI++
Sbjct: 23 GVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----DSAVPREELFISS 78
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDA 188
K+WN E A +L+ L LDY+DLYL+HWP+ + ++WR +E
Sbjct: 79 KVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK---------YRDSWRAMERL 129
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
++K IG++NF + L +L KP Q+E H Q ++ ++ + + +
Sbjct: 130 HDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKYLAEQNIAHAAW 189
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SP +G + +PV++ IA+K+ + Q++L+W + R + PK++ R+
Sbjct: 190 SPLA----------KGILMQNPVITEIAKKHQASVDQVILQWHLNRNTIIFPKSITSSRI 239
Query: 309 EENINIFDFTLTPDEVEKINGFDTHTR 335
EEN + F L ++EKI+ +T R
Sbjct: 240 EENSRLSYFQLDASDMEKIDRLETGKR 266
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 147 bits (355), Expect = 1e-33
Identities = 92/262 (35%), Positives = 145/262 (55%), Gaps = 23/262 (8%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQH 135
DKQL + A+ G+RH D A +Y T +EIG A+K G+ R+D+FIT K + H
Sbjct: 36 DKQLIGTLELALRSGFRHIDGAEIYGTNKEIGIALK---NVGL-NRKDVFITDKYNSGNH 91
Query: 136 -------RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDA 188
+ A+ L+ LGL+Y+DLYL+H+P ++ SH D +E WR LE A
Sbjct: 92 TYDGKHSKHQNPYNALKADLEDLGLEYVDLYLIHFPY--ISEKSHG-FDLVEAWRYLERA 148
Query: 189 QRMGIVKGIGLSNFNKQQLERVLKEGTIK-PDAIQIE--VHLQNVQKEMVEFCQSEGVVV 245
+ G+ + IG+SNF + L+ +L T P QIE +LQ+ +VE+ Q +G+++
Sbjct: 149 KNEGLARNIGVSNFTIENLKSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILI 208
Query: 246 MGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNP 305
Y P G + GP D VLS +++KY + QI+LRW ++R ++PI T
Sbjct: 209 EAYGPLGPITQGR----PGPL--DKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKE 262
Query: 306 KRLEENINIFDFTLTPDEVEKI 327
+R+ + + IFDF L ++ ++I
Sbjct: 263 ERINDVLEIFDFELDKEDEDQI 284
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 147 bits (355), Expect = 1e-33
Identities = 91/304 (29%), Positives = 157/304 (51%), Gaps = 29/304 (9%)
Query: 49 GLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDV--VMRAIDVGYRHFDTASVYETEQEI 106
G+ + E F+ G++ + G + + +V + A+D G DTA +Y TE +
Sbjct: 3 GMQTAE--FDGTGRKVSVIGVGTWSLEGSRSENVRSIRYALDHGVNFIDTAEMYGTEDIV 60
Query: 107 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 166
GEA+K +RED+FI TK+W T +V ++ +SLKKLG DY+DLY +HWP
Sbjct: 61 GEAIKG------YRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP-- 112
Query: 167 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAIQI 223
+ V ET +E G ++ IG+SNF+ ++++ L + I + ++
Sbjct: 113 ------NPSVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAMSALAKYRIVSNQLEY 166
Query: 224 EVHLQNVQKE-MVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKT 282
V + ++ E + +FC+ G+ ++ YSP HG + G ++ L+ I +KYGK
Sbjct: 167 NVATREIEDEGIYDFCRKNGMAIIAYSPLS-----HGK-IFGNEMILETLTDIGKKYGKR 220
Query: 283 TPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKING-FDTHTRYTLPSF 341
Q+ L W I + PIPK P + ENI DFTL+ ++++ ++ + H ++ S
Sbjct: 221 PAQVALNWIIRKGAFPIPKASKPIHMAENIESTDFTLSDEDMKTLDSLYQRHPIRSIASR 280
Query: 342 WQNH 345
++ H
Sbjct: 281 YKGH 284
>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 287
Score = 146 bits (354), Expect = 1e-33
Identities = 88/286 (30%), Positives = 146/286 (51%), Gaps = 12/286 (4%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
GQ+ G ++K QL V A+ VGYR FDTA YE E+++G A+K + +
Sbjct: 7 GQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPRHNIC 66
Query: 121 REDIFITTKL--WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA-DYSHSDVD 177
EDI++T+K+ +++++ + + +N+SL+ L Y+DL L+H+P L+ D + ++
Sbjct: 67 SEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRPLDTEDLNENNKM 126
Query: 178 F-METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVE 236
+ +TW LE G ++ IG+SN+ +E + TI+P QIE H +K +
Sbjct: 127 YRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQIEYHPHFQRKVLRA 186
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKV 296
+C ++ +SP G R T+ G D + IA + T ++L W ++ K
Sbjct: 187 YCNKNEILFQAFSPLG----RGNKTLLG----DSTMERIALCHKTTVANVILAWIMKGKY 238
Query: 297 VPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW 342
+ K+V P R+ EN L+ DE EKING + T Y W
Sbjct: 239 GVVAKSVTPSRVAENYTSLSLELSDDEFEKINGLNLETPYVEDRGW 284
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 146 bits (353), Expect = 2e-33
Identities = 81/240 (33%), Positives = 126/240 (52%), Gaps = 11/240 (4%)
Query: 90 GYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLK 149
G H D A +Y T E+G+A+ + + R IF+T K A ++ +LK
Sbjct: 54 GIIHIDAAEIYRTYPEVGKALSLTEKP----RNAIFLTDKYSPQIKMSDSPADGLDLALK 109
Query: 150 KLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 209
K+G DY+DLYL+H P + + E W+ +E + G K IG+SNF + L+R
Sbjct: 110 KMGTDYVDLYLLHSPF---VSKEVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQR 166
Query: 210 VLKEGTIKPDAIQIEVH--LQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKI 267
+LK +KP QIE LQN + +FCQ ++V YSP G L + P
Sbjct: 167 ILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQDDSQPFF 226
Query: 268 DDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKI 327
+ + +++KY K+ QI+LRW +R V+P+ + P+R+ + N+F F LT +EV+KI
Sbjct: 227 E--YVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSFDLTAEEVDKI 284
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 146 bits (353), Expect = 2e-33
Identities = 76/179 (42%), Positives = 108/179 (60%), Gaps = 8/179 (4%)
Query: 174 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEGT-IKPDAIQIEVHLQNVQ 231
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QIE H Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 232 KEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQ 291
K ++ FCQS V V Y P G GS ID+PV+ IA+++GK+ QI++R+Q
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG------GSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQ 257
Query: 292 IERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
I+R V+ IP ++ P ++ENI +FDF LT +++ I + + R + +NH YPF
Sbjct: 258 IQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHNDYPF 316
Score = 111 bits (266), Expect = 7e-23
Identities = 47/94 (50%), Positives = 66/94 (70%)
Query: 73 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 132
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 133 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 166
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
>UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 326
Score = 145 bits (352), Expect = 3e-33
Identities = 90/285 (31%), Positives = 143/285 (50%), Gaps = 32/285 (11%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G + + GV ++ Q D+V +A D GYRH D+A+ Y E A++ +
Sbjct: 51 GYEIPILGYGVYQTPASQCEDLVAKAFDAGYRHVDSAAAYRNEGPCAAAIR----RSSIP 106
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 180
REDIF T+K+ + +L + GL YIDL L+H P G A +
Sbjct: 107 REDIFFTSKIPPRSLSYENTKAQVAKTLMETGLGYIDLMLIHAPYGGRAARKGA------ 160
Query: 181 TWRGLEDAQRMGIVKGIGLSNFNKQQLERV------LKEGTIKP-----DAIQIEVHLQN 229
W+ L +AQ G ++ +G+SN+ L+ + L+E K D Q E+H
Sbjct: 161 -WKALVEAQEEGKIRSLGVSNYGVHHLDEMEVYMKELEEERGKGRGGVIDVGQWELHPWL 219
Query: 230 VQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLR 289
+ +++ +CQ G+V YSP + G + D +L + +KY KT QI+LR
Sbjct: 220 ARSDIISWCQQRGIVAEAYSPL----------IRGERHDSKLLQPLTKKYNKTPAQILLR 269
Query: 290 WQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHT 334
W +++ VP+PKTV P R++EN +IFDF LT +E+E + D ++
Sbjct: 270 WSLQKGFVPLPKTVTPGRIKENADIFDFELTAEEMEGLETGDYYS 314
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 145 bits (351), Expect = 3e-33
Identities = 85/258 (32%), Positives = 141/258 (54%), Gaps = 22/258 (8%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHR-RTEVAQAI 144
A++ GYRH DTA VY E+ IG A+K + + +KREDIFIT+KL + + V Q +
Sbjct: 65 ALEAGYRHIDTAVVYRNEEYIGTALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMV 124
Query: 145 NDSLKKLGLDYIDLYLMHWP------------IGLNADYSHSDVDFMETWRGLEDAQRMG 192
SL L DY+DLYL+HWP G+ + + +W L +R G
Sbjct: 125 RKSLANLQTDYLDLYLIHWPGVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREG 184
Query: 193 IVKGIGLSNFNKQQLERVLKEGT-IKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPF 251
++ IG+SN+ + L+ +L + I P Q+E H Q E++E+C+ G+ + YS
Sbjct: 185 CLRSIGVSNYTVKHLKEMLADCKGIVPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYSSL 244
Query: 252 GSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
GS +T E +D + S+A+ KT Q++LRW IE++V +PK + ++EN
Sbjct: 245 GS-----SNTAE--LREDETVQSVAKSLQKTPVQVLLRWAIEQEVGILPKARSRDHIQEN 297
Query: 312 INIFDFTLTPDEVEKING 329
+ + +F + ++++++NG
Sbjct: 298 VGL-EFEIPAEQMKQLNG 314
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 144 bits (350), Expect = 4e-33
Identities = 85/268 (31%), Positives = 140/268 (52%), Gaps = 20/268 (7%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G + + G K ++ R V AI+ GYR DTA Y E+ +G+AV+ E
Sbjct: 16 GTRMPMLGMGTWPLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVGKAVR----EAGPD 71
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 180
R +IF+TTK H R V +A+ SL++LGLDY+DL+LMHWP+ Y ++
Sbjct: 72 RAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPMPGEGSY-------VD 124
Query: 181 TWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQS 240
+RG+ + + G+ K IG+SNF L+ ++ EG + P+ QI++ + E+ +F +
Sbjct: 125 AYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEG-MTPEVNQIQLDPSRPRLEVRDFLDN 183
Query: 241 EGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V +SP G R V ++ P + A+K+G T VL W++ + +V IP
Sbjct: 184 HDIVTEAWSPLG----RGADGV----LNAPAVLDAAKKHGITPAAAVLAWELNQGIVTIP 235
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKIN 328
K+ NP+ N+ L+ E++ I+
Sbjct: 236 KSANPEHQRTNLEAIGVELSAQEMKAID 263
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 144 bits (350), Expect = 4e-33
Identities = 83/260 (31%), Positives = 134/260 (51%), Gaps = 23/260 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G + +D+ V A+ GYRH DTA +Y E +G+ K + VKRED F+TTK
Sbjct: 18 GTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDGWK----QSGVKREDFFLTTK 73
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
+W + R ++ ++ +SL KL DY+DL L+HWP+ +V ET + + + +
Sbjct: 74 VWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV--------PEVPIAETMKAMNEVK 125
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G V+ IG+SNF L+ A Q+E H Q ++ C++ G+ + YS
Sbjct: 126 EAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPYLDQNAVLTACRAAGMAMTAYS 185
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIER-KVVPIPKTVNPKRL 308
P +G DD V++ IA+ + + QIVLRW I++ V+ IP++ + K +
Sbjct: 186 PI----------AQGKVFDDEVITEIAKAHNVSPAQIVLRWLIDQDSVIAIPRSSSDKHI 235
Query: 309 EENINIFDFTLTPDEVEKIN 328
+ N I D L+ +E +IN
Sbjct: 236 KSNFEIADLKLSQEETGRIN 255
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 144 bits (350), Expect = 4e-33
Identities = 86/269 (31%), Positives = 148/269 (55%), Gaps = 23/269 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI--GEAVKMKVEEGVVKREDIFIT 127
GV + ++ ++D+V A++VGYR FD+A Y E + G A +K G +RED++ T
Sbjct: 27 GVYQVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGVARGIAAWLKHAPGR-RREDVYFT 85
Query: 128 TKLWNTQHRRTEVAQAINDSLKKLG-LDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLE 186
TK+ H +++ SL G L YIDL L+H P+ +D + + TW+ LE
Sbjct: 86 TKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAPM---SDRTRR----LGTWQALE 138
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLK-EGT-IKPDAIQIEVHLQNVQKEMVEFCQSEGVV 244
+A G V+ IG+SN+ +Q L +L EG I+P Q+E++ ++E+V++C+ +
Sbjct: 139 EAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVEINPWLCRQELVQYCRENNIA 198
Query: 245 VMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
V +SP + G ++DDP+L +A +Y K QI++RW I+ + +PK
Sbjct: 199 VQAFSPL----------MRGKRLDDPILQKVAHQYDKGVAQILVRWSIQMGFIVLPKAAK 248
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTH 333
+RL N +I+DF L+ + + ++ D +
Sbjct: 249 KERLAPNFDIWDFELSAETMSELTHSDDY 277
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 144 bits (348), Expect = 8e-33
Identities = 95/299 (31%), Positives = 145/299 (48%), Gaps = 25/299 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK--MKVEEGVVKREDIFIT 127
G ++ + ++ V A+ GYRH D A VY+ E+ IG A K +KRED++IT
Sbjct: 10 GTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWIT 69
Query: 128 TKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----NADYSHSD-------- 175
+KLWN HR V + ++ L +DY+DL+L+HWP+ D D
Sbjct: 70 SKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLE 129
Query: 176 -VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEM 234
V +TWR +E G+VK IG+SN+ L +L IKP QIE+H +
Sbjct: 130 KVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDAT 189
Query: 235 VEFCQSEGVVVMGYSPFGSLVA--RHGS-TVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQ 291
V+FC G+ V YSP G A R S T + ++ L +IA G + + L W
Sbjct: 190 VKFCLDNGIGVTAYSPMGGSYADPRDPSGTQKNVILECKTLKAIADAKGTSPHCVALAWH 249
Query: 292 IER----KVVPIPKTVNPKRLEENINIFDFTLTPDEVEKING--FDTHTRYTLPS-FWQ 343
+++ IPK+ P R+E N + L+ D+++ IN + R+ P+ FW+
Sbjct: 250 VKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKRIRFCDPAIFWK 308
>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
reductase; n=5; Pezizomycotina|Rep: Related to 2,
5-diketo-D-gluconic acid reductase - Neurospora crassa
Length = 289
Score = 144 bits (348), Expect = 8e-33
Identities = 89/269 (33%), Positives = 144/269 (53%), Gaps = 22/269 (8%)
Query: 68 QNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK--MKVEEGV--VKRED 123
Q G+ + V A+ GYR FD+A Y E+E G+A+ + E + R+D
Sbjct: 25 QLGLYMMSGPETTRAVRWALGAGYRGFDSAQWYYNEREAGQAILSFLSSPENTAGLTRKD 84
Query: 124 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWR 183
+ T+KL + V +I+ S+K GL YIDL+L+H P+G + +W+
Sbjct: 85 VHFTSKLRDNSTNYDAVRASISKSVKASGLGYIDLFLLHSPLGGREAR-------LTSWK 137
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVLKEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEG 242
+EDA G VK G+SN+ + L+ V+ IKP QIE H N Q E+ C+ G
Sbjct: 138 AVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPFKIKPLVNQIECHPFNTQPEIRAACEKYG 197
Query: 243 VVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKT 302
+V+ Y+P +AR G ++ PVL+++A+KYG T Q+++RW ++ V +PK+
Sbjct: 198 IVIEAYAP----LAR------GMRMKHPVLTAVAKKYGVTPAQVLVRWSVQHGFVTLPKS 247
Query: 303 VNPKRLEENINIFDFTLTPDEVEKINGFD 331
+RL EN ++ F L +++EK++G D
Sbjct: 248 TKKERLVENADVGRFELAEEDMEKLDGLD 276
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 143 bits (347), Expect = 1e-32
Identities = 89/264 (33%), Positives = 149/264 (56%), Gaps = 22/264 (8%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
+L D ++ A++ GY H DTA VY T E+ AVK + G+ RED+FITTK T R
Sbjct: 51 ELVDSILLALENGYNHIDTAEVYTTHPEVAAAVK---KSGIA-REDLFITTKY--TPGFR 104
Query: 138 TEVA------QAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRM 191
T A + I+ +LK+L DY+DL+L+H P S W + DA++
Sbjct: 105 TFPAISSGPTEFIDRALKELETDYVDLFLIHSPF-FEEKVSRGQT-LESAWAEVIDAKKA 162
Query: 192 GIVKGIGLSNFNKQQLERVLKEG---TIKPDAIQIEVH--LQNVQKEMVEFCQSEGVVVM 246
G V+ IG+SNF+K+ LER K P QIE H LQN +++F Q +++
Sbjct: 163 GKVRHIGVSNFSKEHLERTFKVAGNPDFYPKVNQIEFHPYLQNQSPGIIKFAQENDILIE 222
Query: 247 GYSPFGSL--VARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
Y P +L + ++G VE + + ++ +A+KYGKT QI+LR+ +++K++PI +
Sbjct: 223 AYGPLSTLFRIKQNGVDVEDHPLKE-LIPKLAEKYGKTDAQILLRYTLQKKILPITTSSK 281
Query: 305 PKRLEENINIFDFTLTPDEVEKIN 328
R+ +++ +++F ++ ++V +I+
Sbjct: 282 LDRIRQSLEVYNFEISDEDVAEID 305
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 143 bits (347), Expect = 1e-32
Identities = 97/291 (33%), Positives = 160/291 (54%), Gaps = 36/291 (12%)
Query: 70 GVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 128
G V +D +L++ V+ A+ GYRH DTA Y TE+ IG+A+K EEG+VKRED+FITT
Sbjct: 24 GTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALKQLFEEGIVKREDLFITT 83
Query: 129 KLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH--------------- 173
K+W + R E ++++ SL LGLDY+DL+L HWP+ L+ D +
Sbjct: 84 KVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLHGDENGLPPQPRDKDGKLIYD 141
Query: 174 ----SDVDFMETWRGLED-AQRMGIVKGIGLSNFNKQQLERVLKE-GTIKPDAIQIEVHL 227
S + +++ + LED VK IG+SN++ +L ++L KP QIE H
Sbjct: 142 DDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLRKLLAAVRKHKPVVNQIEYHP 201
Query: 228 QNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIV 287
Q+++V++C GV + YSP GS +G+ P + +++ +A KY + +I
Sbjct: 202 LLPQQDLVKYCYDNGVHISAYSPVGS----NGA----PVLKLQLINELASKYDVSVNEIA 253
Query: 288 LRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKIN--GFDTHTRY 336
+ I + +P++ N +R++ I + + LT +E+ + G ++ TRY
Sbjct: 254 NAYHILQGRSVLPRSSNLERIKSIIRLPN--LTTEELNALYQIGVESPTRY 302
>UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces
cerevisiae Probable oxidoreductase YJR096W; n=2;
Yarrowia lipolytica|Rep: Similar to sp|P47137
Saccharomyces cerevisiae Probable oxidoreductase YJR096W
- Yarrowia lipolytica (Candida lipolytica)
Length = 287
Score = 143 bits (346), Expect = 1e-32
Identities = 82/256 (32%), Positives = 140/256 (54%), Gaps = 19/256 (7%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGV-VKREDIFITTKLWNTQHRRTEVA 141
V A+++GYR FDTA+ Y+ E + + + ++ VKRED++ TK+ + +
Sbjct: 35 VTEALNLGYRLFDTANEYQNETDTAKGISEWLKSNPNVKREDVWYCTKIDDARGGYEGTK 94
Query: 142 QAINDSLKKL---GLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIG 198
+ ++L K GLDYID+ ++H P H++ M+ W+ L + G ++ +
Sbjct: 95 SRVEEALTKAKVGGLDYIDMLIIHAPYTAPP---HTETR-MKVWKALSEFVDDGKIRTLA 150
Query: 199 LSNFNKQQLERVLKEGT-IKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVAR 257
+SN+ + L+ T KP QIE NV +++ ++C +VV YSP
Sbjct: 151 VSNYGVKHLKEFWDADTKYKPVLNQIESSPWNVHQDIHDYCNEHDIVVEQYSPL------ 204
Query: 258 HGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDF 317
+ G K D+P + S+A+KY KT QI++RW I++ ++PIPK+ P+R + N ++FDF
Sbjct: 205 ----IRGKKFDEPGVQSLAKKYNKTPAQILIRWGIDKGMLPIPKSDQPQRQKSNADVFDF 260
Query: 318 TLTPDEVEKINGFDTH 333
LTPDEV + D++
Sbjct: 261 KLTPDEVTALQDLDSY 276
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 142 bits (345), Expect = 2e-32
Identities = 83/258 (32%), Positives = 132/258 (51%), Gaps = 22/258 (8%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + D ++ ++ A++ G+RHFDTA +Y+ E +G A+ E +RED+F+TTK
Sbjct: 17 GVFRMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRAL----ERAGARREDLFLTTK 72
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
+W + + A ++++SL+KL +D +DL L+HWP +H +V L +
Sbjct: 73 VWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP-------AH-EVPVAAQIERLNAVK 124
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
G + IG+SN N Q+ + Q+E+H Q +V + V V Y
Sbjct: 125 DAGKTRFIGVSNQNIAQMRESIARSAAPIVTNQVELHPYLPQHSLVAAARDSAVAVTAY- 183
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
+G +G DPVL I +YGK+ Q+ LRW +++ V + KT NP R+
Sbjct: 184 -YGM--------ADGAVPKDPVLQQIGARYGKSAAQVGLRWLVQQGYVALSKTANPARVA 234
Query: 310 ENINIFDFTLTPDEVEKI 327
ENI IFDF L ++ I
Sbjct: 235 ENIAIFDFALDETDMAAI 252
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 141 bits (342), Expect = 4e-32
Identities = 80/271 (29%), Positives = 140/271 (51%), Gaps = 25/271 (9%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK 120
G+Q G + +++ V AIDVGY DTA++Y E+ +G+ GV +
Sbjct: 12 GRQIPQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVGK--------GVGE 63
Query: 121 REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFME 180
DIF+ TK+WN +A L++LG +++D+ L+HWP D F++
Sbjct: 64 WSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPC------PEKD-QFVD 116
Query: 181 TWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQS 240
TW+ L + + G K IG+SNF ++ L+R++ E + P QIE+H Q++M + +
Sbjct: 117 TWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIELHPSFQQRDMRKVHED 176
Query: 241 EGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
G+V +SP G +G + + V+ +IA++ G+ ++LRW I+ + PIP
Sbjct: 177 LGIVTQSWSPLG----------QGKGMSNEVIEAIAEETGQPETAVILRWHIQHGLCPIP 226
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFD 331
K + +E N F L+ +++ +I+ D
Sbjct: 227 KASSRDHIEANFKALSFELSDEQMGRIDALD 257
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 141 bits (342), Expect = 4e-32
Identities = 70/170 (41%), Positives = 104/170 (61%), Gaps = 8/170 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
D V A+ +GYRH D A +Y E+EIG +K E+ VVKRED+FIT+KLW T H +V
Sbjct: 33 DAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDV 92
Query: 141 AQAINDSLKKLGLDYIDLYLMHWP-------IGLNADYSHSDVDFMETWRGLEDAQRMGI 193
+A+N +LK L L+Y+DLYL+HWP +G+ + + VD TW+ +E G
Sbjct: 93 PEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE-NLLPVDIPSTWKAMEALYDSGK 151
Query: 194 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGV 243
+ IG+SNF+ ++L +L+ + P Q+E H Q ++ EFC+S+GV
Sbjct: 152 ARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGV 201
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 141 bits (341), Expect = 5e-32
Identities = 85/293 (29%), Positives = 133/293 (45%), Gaps = 43/293 (14%)
Query: 46 DQAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 105
D G + A G C +++G + D + A+D GYR D+A +Y E
Sbjct: 367 DWDGSREQAIRLPAIGFGCSRYRDGTYIDR----ADSIAAALDAGYRLLDSAELYGNEHR 422
Query: 106 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 165
IG ++ G R +FI K+W T HRR + A SL +LG+D D Y +HWP
Sbjct: 423 IG---RILAAPGAPDRRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPE 479
Query: 166 GL--------------------------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGL 199
L D V W LE G + +GL
Sbjct: 480 ALAHRGSLTRLAEKSVARQEALTFPKNDRGDIETDSVSLQRAWENLEALHERGWTRTLGL 539
Query: 200 SNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHG 259
N ++ QLE V++ GT++P +Q+E H Q +++E+C G+ V+ +SP +
Sbjct: 540 CNVSQTQLETVIETGTVRPALVQVERHPYQPQTDLIEYCHERGIRVVAHSPLSA------ 593
Query: 260 STVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENI 312
+D+PVL++IA++YG + +VL W + + VVPIP + P + EN+
Sbjct: 594 ----PGLLDEPVLAAIAEEYGLSPAGVVLAWNVTQGVVPIPSSTTPSHIVENL 642
>UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22;
Pezizomycotina|Rep: Aldehyde reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 295
Score = 140 bits (340), Expect = 7e-32
Identities = 80/249 (32%), Positives = 137/249 (55%), Gaps = 25/249 (10%)
Query: 84 MRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQA 143
++A++ GYRH D+A Y E+E A+K + + R IF TTK+ + + +A
Sbjct: 51 LKALETGYRHIDSAKYYANEKECAVAMK----KSGIDRSKIFFTTKVPASSMSYEKAKEA 106
Query: 144 INDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF- 202
I S+ L YIDL L+H P G + WR L +AQ+ G V+ IG+SN+
Sbjct: 107 IEQSVAATDLGYIDLILLHAPYG-------GKEGRLGAWRALVEAQKAGHVRSIGVSNYG 159
Query: 203 --NKQQLERVLKEGTIKPDAI-QIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHG 259
+ ++LE + G ++ Q E+H ++++V + + VV+ YSP
Sbjct: 160 IHHLEELEEYINSGVGGEISVGQYEIHPWCAREDIVAWLKKRNVVIEAYSPL-------- 211
Query: 260 STVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTL 319
V+ ++D+PVL ++A+K+ KT QI++RW +++ VP+PK+V R+ EN +FDF L
Sbjct: 212 --VQAQRLDEPVLQNLAKKHNKTGAQILIRWSLQKGYVPLPKSVTDSRIVENTQVFDFEL 269
Query: 320 TPDEVEKIN 328
+ +++E +N
Sbjct: 270 SGEDMESLN 278
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 140 bits (339), Expect = 1e-31
Identities = 82/262 (31%), Positives = 129/262 (49%), Gaps = 24/262 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + Q +V D+GYR DTA+ YE E+ +GE ++ + FITTK
Sbjct: 21 GVYQLNPAQAESMVALGYDLGYRAVDTAAWYENEEGVGEGLRSRHARS-------FITTK 73
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
L R A++ S++ LG+ ++LYL+HWP + ETW+ L +
Sbjct: 74 LMPQDMGRVNCFVALDKSIRNLGVTSLNLYLIHWP-------GQDRKRYEETWQTLIQIR 126
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+G IG+SNF L+ ++ + + P QIE+H QKE+ + G+V +S
Sbjct: 127 AIGKASSIGVSNFTIDHLDHIIADSGVVPAVNQIELHPYFQQKELRAYHAERGIVTTSWS 186
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P G G ++DPV+ IA K+GKT Q+VL W + + IPK + RL+
Sbjct: 187 PLG----------RGAALNDPVIREIALKHGKTPAQVVLNWHLSLGLTVIPKASSKARLQ 236
Query: 310 ENINIFDFTLTPDEVEKINGFD 331
EN+ F L +++++I D
Sbjct: 237 ENLEADSFALDEEDMQRIESLD 258
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 140 bits (338), Expect = 1e-31
Identities = 74/246 (30%), Positives = 138/246 (56%), Gaps = 21/246 (8%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
A+ GYRH DTA Y E+ +G+AV+ + + R DIF+T+KL + + +
Sbjct: 39 ALKNGYRHIDTAYAYHNEESVGKAVR----DSGIDRRDIFVTSKLPAEIKSYDKALKTFD 94
Query: 146 DSLKKLGLDYIDLYLMH--WPIG-LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
+++ GL+ +DLYL+H WP ADY+ ++ E W+ +E+ G + IG+SNF
Sbjct: 95 ETMGNFGLEQLDLYLIHAPWPWSEKGADYTKENI---EVWKAMEEIYESGRCRAIGVSNF 151
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
+ L+ V++ IKP QI + + Q+++ FCQ G++V YSP +
Sbjct: 152 SVSDLKAVMENAKIKPMVNQIRYFIGHTQEDVTAFCQDNGILVEAYSPLAT--------- 202
Query: 263 EGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPD 322
G +++ + IA KYGKT PQ+ + + +++ V+P+PK+ + + +N ++ DF ++ +
Sbjct: 203 -GKILENAEIQKIADKYGKTLPQVCICYCLQKGVLPLPKSTHEAFILQNADV-DFEISSE 260
Query: 323 EVEKIN 328
+++ ++
Sbjct: 261 DMQYLD 266
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 139 bits (337), Expect = 2e-31
Identities = 83/262 (31%), Positives = 148/262 (56%), Gaps = 29/262 (11%)
Query: 74 SKDKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL 130
S+D+++ +++ AI +GY H DTA Y TE+ IG+A+K +RED+FI +K+
Sbjct: 32 SRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELIGKAIKD------FRREDLFIVSKV 85
Query: 131 WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQR 190
W T RR ++ +++ ++LK+L DY+DLYL+HWP + ++ ET + + R
Sbjct: 86 WPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP--------NPEIPLEETLSAMAEGVR 137
Query: 191 MGIVKGIGLSNFNKQQLERVLKEG--TIKPDAIQIEVHLQNVQKE-MVEFCQSEGVVVMG 247
G+++ IG+SNF+++ LE + + I D ++ + ++ +++ ++EFCQ GV ++
Sbjct: 138 QGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVKYNIEDRDPERDGLLEFCQKNGVTLVA 197
Query: 248 YSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIER-KVVPIPKTVNPK 306
YSP R E K L IA+ +G T QI+L W + + VV IPK +
Sbjct: 198 YSPL-----RRTLLSEKTK---RTLEEIAKNHGATIYQIMLAWLLAKPNVVAIPKAGRVE 249
Query: 307 RLEENINIFDFTLTPDEVEKIN 328
L EN+ + L+ +E++ ++
Sbjct: 250 HLRENLKATEIKLSEEEMKLLD 271
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 139 bits (337), Expect = 2e-31
Identities = 86/258 (33%), Positives = 140/258 (54%), Gaps = 24/258 (9%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
GV + ++ D V +AI +GYR DTA Y E+E G +K+ VKRE+IF+TTK
Sbjct: 23 GVFQIPKEETADCVKKAISIGYRLIDTAQAYHNEKETGLGIKLSG----VKREEIFLTTK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
+W + + R +++ +SLK+L Y+DL L+H P G ++ + ++ LE
Sbjct: 79 VWVSNYERCY--ESVIESLKRLDTSYLDLILLHQPFG----------NYYKAYQDLERLY 126
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+ V+ IG+SNF ++ + IKP QIE++ + + E + VV ++
Sbjct: 127 KENKVRNIGVSNFWDNRIIDLCFFNQIKPMVNQIEINPFHQRIEDRFYNDKYKVVSQAWA 186
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
PF ++G +P L I +KY KT Q++LRW ++ VV + KTVN R++
Sbjct: 187 PFAE--GKNGL------FTNPTLVEIGKKYNKTPAQVILRWLVQSNVVALCKTVNESRMK 238
Query: 310 ENINIFDFTLTPDEVEKI 327
EN +IFDF L+ +++KI
Sbjct: 239 ENFDIFDFELSKQDLDKI 256
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 139 bits (337), Expect = 2e-31
Identities = 79/256 (30%), Positives = 134/256 (52%), Gaps = 20/256 (7%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQH 135
+ + V A+ GYR DTA Y E+ +G ++ V R ++FI++K H
Sbjct: 36 EDECETAVRFALQSGYRLVDTAFQYRNEEAVGRGIRT----AGVPRSELFISSKFNKESH 91
Query: 136 RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVK 195
V +A ++SL+KLGLD++D+++ HWP+ Y ++ W+GL G VK
Sbjct: 92 SIDGVQRAYDESLRKLGLDHLDMFMCHWPVPALGKY-------VDAWKGLVKLLEEGRVK 144
Query: 196 GIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLV 255
IG+SNF L+ ++ + PD QI++ + E + G+V +SP G
Sbjct: 145 AIGVSNFKPAHLKDIIDATGVVPDVNQIQLSPDLARTEPRAVHRLLGIVTEAWSPIG--- 201
Query: 256 ARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIF 315
S + +P++ IAQ+ K+ Q++LRW +++ +VPIP+ +P L+EN+++F
Sbjct: 202 --RSSGLRA----NPLIIEIAQRLDKSPAQVLLRWHVQQDIVPIPQASDPLWLKENLSVF 255
Query: 316 DFTLTPDEVEKINGFD 331
DF+LT E+ I D
Sbjct: 256 DFSLTAGEMASIRKLD 271
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 139 bits (336), Expect = 2e-31
Identities = 83/241 (34%), Positives = 133/241 (55%), Gaps = 19/241 (7%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQH 135
+++++++V AI GYRH D A+ Y E+ IG+A+K E + R+++ + W H
Sbjct: 30 NEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDAIK----ESGISRDEL---AQPW---H 79
Query: 136 RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVK 195
+V +A++ SL+ LGL+Y+ + P N DY S + ETW+ +E G K
Sbjct: 80 EPKDVERALDLSLEALGLEYVPHAYLPGPN--NVDYERSR-KYTETWQAMEKLVDSGKAK 136
Query: 196 GIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG--- 252
IGLSNFN + +R+L+ I+P Q+E H Q E++ FC+ E + +M + P G
Sbjct: 137 AIGLSNFNILKTKRILEIARIRPAVNQVEAHPYFPQHELLAFCEKEHIHLMAHQPLGGKP 196
Query: 253 -SLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
+VA H + + GP D + + IA + G T Q++L W ++R IPKT N RL EN
Sbjct: 197 VGVVAPH-ADIPGPLFDTKI-AQIAAQTGMTPAQVILSWAVQRGTSIIPKTSNESRLSEN 254
Query: 312 I 312
+
Sbjct: 255 L 255
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 139 bits (336), Expect = 2e-31
Identities = 83/267 (31%), Positives = 130/267 (48%), Gaps = 26/267 (9%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V ++VGY H DTA Y+ E EIGEA+ RED+F+T+K+ V +
Sbjct: 18 VRAGLNVGYAHVDTAEGYKNESEIGEAL------ADYDREDVFLTSKVLPKHLDYESVIE 71
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
A SL +LG DY+DLYL+HWP + ET + G ++ +G+SNF
Sbjct: 72 ACEASLDRLGTDYLDLYLVHWP--------NPATSIRETMNAMATLHDQGKIRNVGVSNF 123
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
+ QL + QIE H N Q ++VEFC+ VV +P G
Sbjct: 124 SAYQLGAAQHVADVPIAVNQIEYHPWNTQDQVVEFCRDTDTVVEAAAPLGRTKV------ 177
Query: 263 EGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPD 322
D ++ +++KY ++ QIVL+W +E VV +PK+ +P+ + +N ++FD+ L
Sbjct: 178 ----FADDIIQDLSEKYDRSPAQIVLKWAVENNVVVLPKSSSPEHVRQNFDLFDWELDAT 233
Query: 323 EVEKINGFDTHTRY--TLPSFWQNHPY 347
+ E+I+ + T + W N Y
Sbjct: 234 DRERIDAIEREQAVYDTGINDWDNDTY 260
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 138 bits (334), Expect = 4e-31
Identities = 82/257 (31%), Positives = 135/257 (52%), Gaps = 22/257 (8%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQH 135
D V A+ +GYRH DTA Y E E+G+A+K + + R+ I++T+KLW +
Sbjct: 28 DGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQAIK----DSGIPRDQIWVTSKLWLQDY 83
Query: 136 RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVK 195
++AI+ SL KL LDYIDLYL+H P G D W+ +E AQ+ G +K
Sbjct: 84 GFDAASRAIDRSLTKLRLDYIDLYLIHQPYG----------DVPGAWQAMEAAQKAGKLK 133
Query: 196 GIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLV 255
IG+SN ++ + + P Q+E + Q+ + + ++ V + ++P G
Sbjct: 134 SIGVSNMTPTLWQKFVPQFETIPAVNQVEFNPYFQQQPLRQLLAAQDVKLEAWAPLGQ-- 191
Query: 256 ARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIF 315
G+ +P++ +A KY K QI+LR++ + V+ PK+V+ R++ N +IF
Sbjct: 192 ---GNQA---LFKEPIIQQLAIKYHKDAGQIILRFEHQEGVIVFPKSVHSARIKSNRDIF 245
Query: 316 DFTLTPDEVEKINGFDT 332
DF LT E+ ++ DT
Sbjct: 246 DFELTSTEMAQLRALDT 262
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 138 bits (333), Expect = 5e-31
Identities = 77/252 (30%), Positives = 137/252 (54%), Gaps = 24/252 (9%)
Query: 80 RDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTE 139
+ V A+D Y DTA+VY E+ +G ++ + R++IF+ TKLW + R
Sbjct: 28 QSAVTYALDNDYTLIDTANVYVNERAVGRGMRASSKA----RDEIFLETKLWPSFFER-- 81
Query: 140 VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGL 199
A A+ ++L++LG DYIDL ++H P G D + +R LE A + G ++ IGL
Sbjct: 82 -ASAVEETLERLGTDYIDLMILHQPAG----------DTVAGYRILEKAHKEGKIRAIGL 130
Query: 200 SNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHG 259
SNF+ Q +R+L E + P Q+E H Q E+ + + + + P G R
Sbjct: 131 SNFDVAQTQRILDECEVVPTINQVECHPYFPQTELKALLKDHNITLQAWYPLGG---RGN 187
Query: 260 STVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTL 319
++ + +P++ +A+++ K+ Q++LRW I++ + IP + P + +NI++FDF L
Sbjct: 188 DSI----MSEPIVQGLAEEHSKSPAQVLLRWHIQQGHIVIPGSKTPSHIAQNIDLFDFAL 243
Query: 320 TPDEVEKINGFD 331
T +++ +I+ D
Sbjct: 244 TDEDMAQIDSLD 255
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 137 bits (331), Expect = 9e-31
Identities = 82/265 (30%), Positives = 140/265 (52%), Gaps = 20/265 (7%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G K + +V +A+D GYRH DTA+VY E G+A+ E+ VKR DIF+T+K
Sbjct: 25 GAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCEKNNVKRTDIFLTSK 84
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 189
L N + A AI SL LG YIDL+L+ P G + +W+ +E+
Sbjct: 85 LANCSDYYSTRA-AIRSSLHHLG-TYIDLFLIQSPAG-------GKKSRIASWKAMEEFV 135
Query: 190 RMGIVKGIGLSNFNKQQLERVLKEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGY 248
G ++ +G+SN+ + L+ + P QIE+H Q ++V++CQS + + Y
Sbjct: 136 DSGDIRSVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKYCQSHDIAIEAY 195
Query: 249 SPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRL 308
SP G +++D L IA+K + Q+++RW +++ +PI K+ + +
Sbjct: 196 SPL----------THGIRLNDEKLVPIAKKLNISVAQLLIRWSLQKGYIPIIKSTKKEHM 245
Query: 309 EENINIFDFTLTPDEVEKINGFDTH 333
++++F+FT+ D V++++ FD H
Sbjct: 246 LSDLDVFNFTIPDDVVQELSSFDEH 270
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 136 bits (329), Expect = 2e-30
Identities = 82/251 (32%), Positives = 129/251 (51%), Gaps = 26/251 (10%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V A D+GYR DT+ Y T+ IGEA++ + R+DI++ TK+ T+ +
Sbjct: 19 VRAAFDLGYRMVDTSGDYGTQSAIGEAIRASG----LDRDDIYLVTKVEETE----DAYN 70
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
A +L++LGLDY DL L+H P A E WR L A+ G+ + IG+SN+
Sbjct: 71 ATQANLRELGLDYADLILIHRPPRHGAGE--------ELWRALIRAREDGLTRDIGVSNY 122
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
+ + +E ++ P Q+E E+ + G+V+ YSP
Sbjct: 123 SIELIEELVDATGEIPVVNQVEWSPFGHDLELKHYADFNGIVIQAYSPL----------T 172
Query: 263 EGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPD 322
++DD L A+KYGKT Q+++RW +ER VPIPK ++ENI++FDFTL
Sbjct: 173 RATRLDDAALCETAEKYGKTPAQVLIRWNLERGTVPIPKANLHSHMKENISVFDFTLEKS 232
Query: 323 EVEKINGFDTH 333
++E ++ + H
Sbjct: 233 DLESLDSLNEH 243
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 136 bits (328), Expect = 2e-30
Identities = 80/269 (29%), Positives = 148/269 (55%), Gaps = 13/269 (4%)
Query: 61 GQQCGLFQNGVVKSKDKQL-RDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVV 119
G L G K + ++L VV +++VG+R DTA Y E++IG A+K + + +
Sbjct: 13 GYDMPLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLLPKYNL 72
Query: 120 KREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDF 178
+R DIFITTKL + + + + Q + SLK YIDLYL+HWP + ++
Sbjct: 73 QRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATRIPETSTNNPS 132
Query: 179 M--ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE-GTIKPDAIQIEVHLQNVQKEMV 235
+ +TW L D ++ G ++ IG+SNF + L+ +L+ I P Q+E+H Q+E++
Sbjct: 133 LRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVELHPHYRQEELI 192
Query: 236 EFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
++C +G+ + YS G+ G+ + +P++ IA + ++ +++L W +++
Sbjct: 193 KYCNEKGIHIQAYSSLGT----SGNI---NLLRNPIVLKIASQLNVSSARLLLNWALQQG 245
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEV 324
+ IPK VN + +++NI + DF + + +
Sbjct: 246 IGVIPKAVNKEHIKDNIQL-DFLIDEESM 273
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 136 bits (328), Expect = 2e-30
Identities = 83/249 (33%), Positives = 128/249 (51%), Gaps = 21/249 (8%)
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
V+ I+ GYR DTA++Y+ E +G A+ E V RE++F+TTKL + H ++
Sbjct: 23 VLSGIEAGYRLIDTATIYDNEDAVGVALA----ECGVPREELFVTTKLRGSDHVSGDIRG 78
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
A+ SLK LGLD +DL+L+HWP+ + Y V E DA G+V+ +G+SNF
Sbjct: 79 AVERSLKNLGLDRLDLFLIHWPLPRHNRY----VAAFEAMLACRDA---GLVRHVGVSNF 131
Query: 203 NKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTV 262
+ L RV+ E P QI++ + + GV +SP G
Sbjct: 132 LETHLRRVVAETGESPAVNQIQMDPSLARLPVRRADDELGVSTQSWSPLG---------- 181
Query: 263 EGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPD 322
G + PV++ IA++ +T Q+VL W + VVP+ ++ NP R EN+ D LT
Sbjct: 182 RGEVLGSPVVTDIARRLDRTPAQVVLAWHFAQGVVPVARSANPARQAENLAALDVRLTAA 241
Query: 323 EVEKINGFD 331
+V+ +N D
Sbjct: 242 DVDALNRLD 250
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 135 bits (327), Expect = 3e-30
Identities = 80/276 (28%), Positives = 137/276 (49%), Gaps = 25/276 (9%)
Query: 67 FQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFI 126
F G + KD+ + D V A+ +GYR DTA +Y+ E ++G+A+ + V R+ +F+
Sbjct: 6 FGLGTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA----DAGVPRDQLFV 61
Query: 127 TTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLE 186
TTK+W + R + ++ +SL+KLG DY+DL L+HWP V E L
Sbjct: 62 TTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP------SPKDQVPMREYLEALA 115
Query: 187 DAQRMGIVKGIGLSNFN---KQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGV 243
DA+ G+ + IG+SNF +Q +L I + I++ +LQN + ++ F + +G+
Sbjct: 116 DAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVHPYLQN--RTLIAFLREQGI 173
Query: 244 VVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTV 303
V Y + G + DPV+ +IA+++ T Q+ L W +++ IP +
Sbjct: 174 HVTSYM----------TLAVGEVLKDPVIQAIARRHDATPAQVTLAWALQQGYSVIPSST 223
Query: 304 NPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
LE N+ L+ ++ +I D R P
Sbjct: 224 KRANLESNLKAQSLHLSEQDMAEIAALDRGERLANP 259
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 135 bits (327), Expect = 3e-30
Identities = 87/263 (33%), Positives = 140/263 (53%), Gaps = 23/263 (8%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
+L +V+ A++ G+ H D A Y TE+E+G A++ E + RE +FITTK+
Sbjct: 37 ELIEVLKAALEKGFHHIDAADSYGTEREVGIAIR----ESGIPREQLFITTKVLEGWK-- 90
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGI 197
+V A++ SL++L LDY+DLYL+H P + + D W+GLE + G + I
Sbjct: 91 -DVPGALDASLERLQLDYVDLYLLHNPYVIP-----NLTDIQSAWKGLEAVKATGKARSI 144
Query: 198 GLSNFNKQQLERVLKEGTIKPDAIQIEVH--LQNVQKEMVEFCQSEGVVVMGYSPFGSLV 255
G+SNF + LE +L+ ++ P Q+E H LQ + + + + G+ V + +
Sbjct: 145 GVSNFQRNHLEAILETCSVVPAINQLEYHPYLQR-SHDFIPWMRERGIEVSSFKTLAPVT 203
Query: 256 ARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIF 315
G GP +D+P L+SIA K+ TT +VL W I + +VPI T +R+EE I
Sbjct: 204 VGKG----GP-LDEP-LASIAAKHNITTSAVVLNWVISQNIVPITTTTKRERMEEYIAAI 257
Query: 316 DFTLTPDEVEKIN--GFDTHTRY 336
L +E+++I G H R+
Sbjct: 258 SLQLDREELDEITQIGLRHHFRW 280
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 135 bits (326), Expect = 4e-30
Identities = 71/254 (27%), Positives = 132/254 (51%), Gaps = 7/254 (2%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K++ LR V+ GYR DTA VY E +IG ++ + +KREDI+IT+KL +
Sbjct: 23 KEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKREDIWITSKLAPSN 82
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWP-IGLNADYSHSDVDFMETWRGLEDAQRMGI 193
+ ++I +SL L ++Y+DL L+HWP L ++ + +E+W + + G
Sbjct: 83 AGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENPANKKLRVESWNVMCEMMAEGK 142
Query: 194 VKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 253
++ +G+SNF LE + K+ + P Q+E H Q ++V++C + YS GS
Sbjct: 143 LRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQDDLVKYCNENNIHFQAYSSLGS 202
Query: 254 LVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENIN 313
T ++P++ +AQKY P ++L + + + +P+T NP+ + N
Sbjct: 203 ------PTYRKQLSEEPLIKELAQKYNVEIPVLLLGFAYCQGISVLPRTTNPEHVATNFK 256
Query: 314 IFDFTLTPDEVEKI 327
+ +T ++++++
Sbjct: 257 VTKLAITQEDIDRL 270
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 134 bits (325), Expect = 5e-30
Identities = 86/278 (30%), Positives = 136/278 (48%), Gaps = 46/278 (16%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G SK ++ + V A+ +GYRH D A+ Y E E+G K + V R+ IFIT+K
Sbjct: 21 GTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNGWK----KSGVPRDQIFITSK 76
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM--------------------HWPIG--- 166
LWNT H V +A+N +LK L DY+DLYL+ HWP+
Sbjct: 77 LWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIHDLLSLLTNNKIHWPVAFEH 136
Query: 167 ----------LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTI 216
++ + +++ +TW LE G V+ IG+SNF +++E +LK I
Sbjct: 137 TNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTIEKIEELLKTARI 196
Query: 217 KPDAIQIEVHLQNVQKEMVEFCQSE--GVVVMGYSPFGSLVARHGSTVEGPKI-DDPVLS 273
P QIE H Q + ++ + + ++ + YSP G+ + P++ DDP +
Sbjct: 197 PPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSPLGNNI------YNAPRVVDDPTVK 250
Query: 274 SIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
IAQK K +++ W ++R +PK+V P R+E N
Sbjct: 251 EIAQKLNKDPAALLISWAVQRGTSVLPKSVTPSRIESN 288
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 134 bits (324), Expect = 6e-30
Identities = 88/282 (31%), Positives = 134/282 (47%), Gaps = 25/282 (8%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGV--VKREDIFITTKLWNTQHRRT 138
+ + A+ +GYRHFD A Y E+ IGE K + VKRED++I +KLW H
Sbjct: 19 EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWPNFHEPE 78
Query: 139 EVAQAINDSLKKLGLDYIDLYLMHWPIGL----NADYSHSD---------VDFMETWRGL 185
+VA I+++L+ L L+Y+D++LMHWP+ + + DY+ SD +TW +
Sbjct: 79 KVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKGGTLLGTTPIRKTWEAM 138
Query: 186 EDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVV 245
E + IG+SN L +L IKP Q E ++EFC S G+ V
Sbjct: 139 EACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYV 198
Query: 246 MGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL-----RWQIERKVVPIP 300
Y P G R + P + DP L +A+K T +++L RW IP
Sbjct: 199 TAYRPLG---GRCRVDAKAP-LTDPALEELAKKANLTVSELILAWHWTRWGTSGTYSVIP 254
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFD-THTRYTLPSF 341
K+ + +R ++N+ LTPD+++ H R SF
Sbjct: 255 KSSDRERQKQNLESVKLRLTPDQMDAFARLGCVHQRTCFTSF 296
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 134 bits (324), Expect = 6e-30
Identities = 68/183 (37%), Positives = 113/183 (61%), Gaps = 8/183 (4%)
Query: 71 VVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKL 130
++ SK+ ++ +++ A+D GYRH DTA Y+ E IGE++K +EG R+D+FI +K+
Sbjct: 25 LLNSKE-EMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKEGKYSRKDLFIVSKV 83
Query: 131 WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---NADYSHSDVDFMETWRGLED 187
+ ++ + +++ SLK+L LDY+DLY +H+P+G ++ H V W LE+
Sbjct: 84 F--PNKGINMLESVKKSLKELQLDYVDLYYLHFPLGFLSEKEEFVHLPVHV--AWAQLEE 139
Query: 188 AQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
A R+G+ K IG+SNFN L +L +KP + Q+EV + QK +++FCQ G+ V
Sbjct: 140 AHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVSVFIQQKNLIKFCQRFGIHVTA 199
Query: 248 YSP 250
Y+P
Sbjct: 200 YAP 202
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 134 bits (323), Expect = 8e-30
Identities = 89/306 (29%), Positives = 144/306 (47%), Gaps = 18/306 (5%)
Query: 46 DQAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 105
D A + EL A G+ G + ++ V A+ GYR D A+VY E +
Sbjct: 9 DPALVPRRELRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQ 68
Query: 106 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 165
+GEA+ V GV R+++F+ +K+WN H + +++ SL+ L LD++D +HWP
Sbjct: 69 VGEALAGAVAGGV-DRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPF 127
Query: 166 GLNADYSHSDVD-------------FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 212
N +D D ++ W LE G+V+ +G SN +L+ +L+
Sbjct: 128 P-NHHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLR 186
Query: 213 EGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKID--DP 270
+ I P ++E+H Q E+ C G+ +GYSP GS G +D DP
Sbjct: 187 DARIPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSPLGSPSRPERDRTPGDVVDTEDP 246
Query: 271 VLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENIN-IFDFTLTPDEVEKING 329
V+ IA+++G + L+W + R VPIP +V P + N+ + + LT EV +
Sbjct: 247 VVVRIAREHGVHPALVCLKWAVARGQVPIPFSVKPAQYTANLRAVVEDPLTAQEVADLAA 306
Query: 330 FDTHTR 335
D R
Sbjct: 307 ADRGER 312
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 132 bits (318), Expect = 3e-29
Identities = 92/283 (32%), Positives = 146/283 (51%), Gaps = 39/283 (13%)
Query: 53 TELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKM 112
+E++F A G G FQ + ++ +++ V++A+ GYRH DTA+ Y E E+GEA+K
Sbjct: 42 SEMTFPAVG--LGTFQGD---AGNRGVKEAVLQALRCGYRHIDTATAYGNEIEVGEAIK- 95
Query: 113 KVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDY---IDLY---------- 159
E + RE+I +TTKL T HR ++V +A++ SL++L L+Y + LY
Sbjct: 96 ---ESRIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHA 152
Query: 160 --------LMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 211
+ P G D+ TW +E G +K IG+SNFN +LER+L
Sbjct: 153 YSPGPDNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLL 212
Query: 212 KEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPV 271
I P QIE+H Q E+V FC++ G+ ++ + P G P D P
Sbjct: 213 GSARIPPAVNQIELHPYLPQVELVRFCKANGIHLVAHQPLGGKPV----AAVNPNADRP- 267
Query: 272 LSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINI 314
A K+ ++ QI+L W +++ + IPKTV R+ EN+++
Sbjct: 268 ----ASKHERSPAQIILSWIVQQGISVIPKTVRQSRMVENLDL 306
>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 293
Score = 131 bits (316), Expect = 6e-29
Identities = 83/268 (30%), Positives = 137/268 (51%), Gaps = 24/268 (8%)
Query: 67 FQNGVVKSKDKQLRDVVMRAID-VGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIF 125
F G + + + ++ A D GYRH DTA Y E + GEAV+ E V R ++F
Sbjct: 30 FGIGAWDMRGSECKQALLNAFDKAGYRHVDTARYYRNEADCGEAVR----ECSVPRSELF 85
Query: 126 ITTKLW-NTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRG 184
TTK++ N ++ A+ DSL K GLDY+DL L+H P G +++W
Sbjct: 86 YTTKVYLNEMGGGSKTRLAVEDSLAKAGLDYLDLVLLHAPDG-------GKKFRLDSWDT 138
Query: 185 LEDAQRMGIVKGIGLSNFNKQQLERVL-KEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGV 243
L + + G V+ +G+SNF ++ ++ + + P QIE H QKE+ ++ +
Sbjct: 139 LTELVQEGKVRSLGVSNFGPHHIQELIDSKPKVLPVCNQIECHPFFAQKEVRAASEAHSI 198
Query: 244 VVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTV 303
+V Y P +AR G DP L +A + GKT Q++LRW ++ +V +PK+
Sbjct: 199 IVQAYCP----LAR------GHYYGDPTLKKVAAETGKTEAQVMLRWLVQHGIVALPKSS 248
Query: 304 NPKRLEENINIFDFTLTPDEVEKINGFD 331
N +R EN F L+ +++++++ D
Sbjct: 249 NLQRQVENAECLTFVLSDEQMKELDALD 276
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 130 bits (315), Expect = 8e-29
Identities = 94/313 (30%), Positives = 158/313 (50%), Gaps = 45/313 (14%)
Query: 23 VPSLKMNNGRDMPAIGLGTYLGFDQAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDV 82
+PSLK+++G ++P +G G ++G S+ +S + + +
Sbjct: 24 IPSLKLSDGNEIPMLGYGLGTANYKSGDSADTIS--------------------EPIVNA 63
Query: 83 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 142
+ A++ GY H D A VY E E+G A+ + + R ++ITTK V Q
Sbjct: 64 TLTALNAGYAHLDGAEVYGNEVELGRAIA----QSKLPRSSLYITTK--TIVRAGDTVTQ 117
Query: 143 AINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 202
+ N SL+KLGLDY+DLYL+H P ++ + WR +E + G+ K IG+SNF
Sbjct: 118 SFNRSLEKLGLDYVDLYLLHSPF-----FAKNPEQLQAAWREMEKIKDSGMAKSIGVSNF 172
Query: 203 NKQQLERV--LKEGTIKPDAI-QIEVH--LQNV--QKEMVEFCQSEGVVVMGYSPFGSLV 255
L+ + + G P + QIE H LQ+V +++V FC+ + + + YSP ++
Sbjct: 173 LISHLQTLFDIPGGLQYPPVVNQIEYHPYLQHVVEGEDLVAFCREKHIAIAAYSPLTAI- 231
Query: 256 ARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENI-NI 314
T P DP+ + +A+KYG + +I RW +++ +V + + N +RL+ + +
Sbjct: 232 -----TKARPGPVDPIYTQLAKKYGVSEAEIAFRWCLDQGIVTLTTSSNEERLKGYLKKL 286
Query: 315 FDFTLTPDEVEKI 327
F LTP EVE I
Sbjct: 287 PSFKLTPKEVEDI 299
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 130 bits (314), Expect = 1e-28
Identities = 85/266 (31%), Positives = 142/266 (53%), Gaps = 26/266 (9%)
Query: 73 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 132
+S D+ + V+ A++ G RH DTA Y EQ++ +K + V R +IFITTK+
Sbjct: 20 RSADEAHQGVIW-ALEAGCRHIDTAQGYGNEQDVARGIK----DAGVARNEIFITTKVKP 74
Query: 133 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMG 192
+ V ++ +SL+KL +D +DL L+HWP N + D++ + + D+ G
Sbjct: 75 DNYGPGAVMPSVRESLEKLRVDQVDLLLLHWPSPHN---KYPLADYLGQFAEVFDS---G 128
Query: 193 IVKGIGLSNFNKQQLE---RVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYS 249
+ + IG+SNF K ++ R+L TI + ++ V++QN + ++++CQ+ G+ V YS
Sbjct: 129 LARQIGVSNFTKAMIDESIRLLDSRTITTNQVECHVYMQN--RPIIDYCQNLGIAVTAYS 186
Query: 250 PFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLE 309
P +AR G + DPVL I + G T+ QI L + I + V IP + R+
Sbjct: 187 P----LAR------GAVVGDPVLEEIGKARGATSDQIALAFLIAKGHVVIPSSSKRGRIM 236
Query: 310 ENINIFDFTLTPDEVEKINGFDTHTR 335
+N TLTP E+++I G + R
Sbjct: 237 QNFEARKITLTPAEIKRIEGLEKGMR 262
>UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2;
Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum
lacusprofundi ATCC 49239
Length = 665
Score = 130 bits (314), Expect = 1e-28
Identities = 86/308 (27%), Positives = 138/308 (44%), Gaps = 43/308 (13%)
Query: 47 QAGLSSTELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 106
+ G + + A G C +++G + D + A+D GYR D+A +Y E I
Sbjct: 366 EKGPGAAAIRLPAVGFGCSRYRDGEYVDRV----DSIATALDAGYRLLDSAELYGNEHRI 421
Query: 107 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 166
GE + G RE +F+ K W T HRR + A S ++LG+D D Y +HWP
Sbjct: 422 GELL---AAPGAPDRERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSA 478
Query: 167 L--------------------------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLS 200
L + + + +DV WR LE G + +G+
Sbjct: 479 LEHRGELNRLAEKPVERQETLTFPEGEDGEPATADVALATAWRNLEAVHERGWARTLGIC 538
Query: 201 NFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGS 260
N ++ QLE VL+ G I P +Q+E H + +VE C G+ V+ +SP +
Sbjct: 539 NVSRAQLETVLETGEIDPALVQVERHPYRPRNGLVELCHGRGIRVVAHSPLSA------- 591
Query: 261 TVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLT 320
+D+PVL++I + G + ++V+ W + VVPIP + + N+ LT
Sbjct: 592 ---PGLLDEPVLNAIGTERGLSPAEVVIAWNASQGVVPIPSSTAESHVVSNLAAGSERLT 648
Query: 321 PDEVEKIN 328
DEV +I+
Sbjct: 649 ADEVARID 656
>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
pacificus|Rep: Aldose reductase - Pristionchus pacificus
Length = 293
Score = 129 bits (312), Expect = 2e-28
Identities = 81/255 (31%), Positives = 126/255 (49%), Gaps = 8/255 (3%)
Query: 79 LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRT 138
L D + A +GYR DTA +Y E +G + +E+ +KREDIFIT+K+ +
Sbjct: 32 LTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLKREDIFITSKVSPINQGKG 91
Query: 139 EVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSD-VDF-METWRGLEDAQRMGIVKG 196
+ ++++ SL L YIDL L+HWP +H D F ET+ LE G ++
Sbjct: 92 KTSKSVLKSLTDLQTPYIDLVLIHWPGTSRLKSNHKDNAKFRAETYVELETLMDEGKIRS 151
Query: 197 IGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVA 256
IG+SN+ + LE +L E I P Q E H E+ E+C+ +G+ YS G
Sbjct: 152 IGVSNYEIKHLETLLAECRILPAINQCECHPHFRNSELAEYCKEKGIHFQAYSSLGG--- 208
Query: 257 RHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFD 316
S VE + D ++ IA + + I+L W + + +P+T R+EEN D
Sbjct: 209 --PSYVEN-LLKDKIIKKIANAHSTSPAVILLAWGLNQGYSILPRTEKVGRIEENWKAKD 265
Query: 317 FTLTPDEVEKINGFD 331
L+ E+++I D
Sbjct: 266 IKLSEKEMKEIGSID 280
>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
baltica OS145|Rep: Aldo/keto reductase - Idiomarina
baltica OS145
Length = 263
Score = 129 bits (311), Expect = 2e-28
Identities = 83/276 (30%), Positives = 131/276 (47%), Gaps = 23/276 (8%)
Query: 67 FQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFI 126
F G + + ++L D+V AID+GY H DTA Y E ++G+A+ + D+F+
Sbjct: 5 FGMGTFRLEGQELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQHTNK------DVFV 58
Query: 127 TTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLE 186
TTK+W + +V ++ S KL D IDL L+HWP + +V ET L+
Sbjct: 59 TTKVWYEKLAYQDVLDSLQVSRDKLQRDTIDLALIHWPS------PNDEVPVEETLDALQ 112
Query: 187 DAQRMGIVKGIGLSNFNKQQLERVLKE-GTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVV 245
AQ+ G++K +G+SNF L R G + QIEVH + + C+ GV V
Sbjct: 113 KAQQDGLIKHLGVSNFTIDLLNRAAAHVGKDEILTNQIEVHPFFQNHAITDACKQMGVKV 172
Query: 246 MGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNP 305
Y P +G +D+ V+ +IA+K+ + Q+ + WQ+ + IP T
Sbjct: 173 TAYLPLA----------KGAVMDNSVMQNIAEKHNVSPAQVAIAWQLANDYIAIPSTTKV 222
Query: 306 KRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSF 341
L+ N + L D+++ I D R P F
Sbjct: 223 DHLKSNFDAQSLKLDQDDMKAIADIDKDDRLIDPDF 258
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 128 bits (308), Expect = 5e-28
Identities = 68/192 (35%), Positives = 114/192 (59%), Gaps = 5/192 (2%)
Query: 72 VKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLW 131
+K + + V AI++GYR D A+VY E +G ++ ++ +KREDI++T+KLW
Sbjct: 49 LKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKREDIWVTSKLW 108
Query: 132 NTQHRRTE-VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQR 190
N H E V + +N +L+ LGL+Y+DLYL+HWPIG +++ ++D ++T++ + +
Sbjct: 109 NDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSN-GAKNLDHVQTYKSMISLPK 167
Query: 191 MGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSP 250
++ IG+SNF+ QL+ V+ GTI P Q+E+H Q V ++ G+ + YSP
Sbjct: 168 SRVL-NIGVSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQQSAWVATHKALGIKMTAYSP 225
Query: 251 FGSL-VARHGST 261
G+ H ST
Sbjct: 226 LGNTNPTYHSST 237
Score = 41.5 bits (93), Expect = 0.061
Identities = 18/63 (28%), Positives = 37/63 (58%)
Query: 265 PKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEV 324
P + +P+L IA++ T Q+ L+W + R + IPK+ + + ++EN+ + LT ++
Sbjct: 269 PLLQNPILIDIAEERNCTPAQVALKWNMGRGISVIPKSSHEEWIKENLQAGECELTHADL 328
Query: 325 EKI 327
K+
Sbjct: 329 TKL 331
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 127 bits (306), Expect = 1e-27
Identities = 61/165 (36%), Positives = 104/165 (63%), Gaps = 3/165 (1%)
Query: 178 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMV 235
F++TW +E+ G+ K IG+SNFNK Q+E VL + +K P QIE H Q++++
Sbjct: 162 FLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLI 221
Query: 236 EFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
FC+S G+ V ++ GS S E +DDP +++IA+K T Q+++++QI+R
Sbjct: 222 HFCRSRGISVTAFACLGSADRSWASADEPSFLDDPQINAIARKNQMTPAQVLIKFQIQRN 281
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR-YTLP 339
+ + K+V+P R++ENI FD+ L+ D+++ + F+++ R YTLP
Sbjct: 282 ITAVVKSVSPHRIKENIKAFDYELSDDDMKTLMSFNSNWRGYTLP 326
Score = 101 bits (241), Expect = 7e-20
Identities = 48/97 (49%), Positives = 62/97 (63%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS + V AI GYRH DTA VYE E E+G V+ +++GVVKRE++FI +K
Sbjct: 19 GTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQAMIDQGVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 166
LW T H + V A +L L LDY+DLYLMH+P+G
Sbjct: 79 LWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMG 115
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 126 bits (305), Expect = 1e-27
Identities = 86/287 (29%), Positives = 150/287 (52%), Gaps = 34/287 (11%)
Query: 52 STELSFEAPGQQCGLFQNGVVKSKDKQLRDV----VMRAIDVGYRHFDTASVY---ETEQ 104
S + F P G ++ G V + D D + R I G H DTA +Y E+
Sbjct: 8 SLKNGFAIPVLGQGTWRMGGVDTPDTANDDADIAAIRRGIATGLCHIDTAEMYAGGHAEE 67
Query: 105 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 164
+G A+K +G+ +R D F+T K+W T R +V +A SLK+LG DYIDLYL+H
Sbjct: 68 LVGIAMK---GQGI-RRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDLYLIH-- 121
Query: 165 IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER--VLKEGTIKPDAIQ 222
+ DV ET R + +R G+++ IG+SNF++++L+R + I + +
Sbjct: 122 ------QVNPDVPEEETIRAMNRLKREGVIRHIGVSNFSEERLKRAQAASDAPIVANQLH 175
Query: 223 IEVHLQNVQK-EMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGK 281
+ ++ +++ ++++C+S+ ++V+ + P + G + P++ ++A+KYGK
Sbjct: 176 YNLRIREIEQCGLLDYCRSQDIMVIAWRP-----------LRGLDLALPLIVTLAEKYGK 224
Query: 282 TTPQIVLRWQI-ERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKI 327
T QI L W + + VV I K NP L EN+ + L ++ E++
Sbjct: 225 TPSQIALNWLLCQENVVTITKAANPLHLAENMGALGWVLEKEDAERL 271
>UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1;
Filobasidiella neoformans|Rep: Oxidoreductase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 321
Score = 126 bits (305), Expect = 1e-27
Identities = 89/269 (33%), Positives = 143/269 (53%), Gaps = 42/269 (15%)
Query: 83 VMRAIDVGYRHFDTAS---VYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTE 139
V +AIDVG+ H DTA VY E+E+G+A+K E + R +++TTK W+ +
Sbjct: 33 VGQAIDVGFDHIDTAQGRIVYHNEEEVGQAIK----ESGLSRNQLWVTTK-WSGIDGKG- 86
Query: 140 VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGL 199
Q+I +SL+KLGL+Y+DLYL+H P D + W+ LE Q+ G K IG+
Sbjct: 87 ARQSIGESLEKLGLEYLDLYLIHSPQVTKGDIKGA-------WKELETLQKEGKTKSIGV 139
Query: 200 S------------------NFNKQQLERVLKEGTIKPDAIQIEVHLQNVQKE--MVEFCQ 239
S +FNK+QL+ +L T+KP QI +H + + ++E+ +
Sbjct: 140 SKQVYYQTIFFASLSDVWDSFNKEQLQELLAHATVKPVVNQILLHPYVITRTAPLLEYLE 199
Query: 240 SEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPI 299
+ +V GYS L +R G GP +D PV + IA++ Q++L W ++ +P+
Sbjct: 200 EQNIVAEGYSTLIPLTSRPG----GP-VDKPV-NQIAERLNVKPEQVLLAWSRAKRAIPV 253
Query: 300 PKTVNPKRLEENINIFDFTLTPDEVEKIN 328
+ RLE +++ D TLT D+V+ I+
Sbjct: 254 TTSSRKARLEGYLDVGDITLTEDDVKAID 282
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.319 0.136 0.410
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 638,277,182
Number of Sequences: 1657284
Number of extensions: 27344609
Number of successful extensions: 71207
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 821
Number of HSP's successfully gapped in prelim test: 548
Number of HSP's that attempted gapping in prelim test: 66084
Number of HSP's gapped (non-prelim): 3392
length of query: 595
length of database: 575,637,011
effective HSP length: 105
effective length of query: 490
effective length of database: 401,622,191
effective search space: 196794873590
effective search space used: 196794873590
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 75 (34.3 bits)
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