Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001348-TA|BGIBMGA001348-PA|IPR001810|Cyclin-like F-box,
IPR006553|Leucine-rich repeat, cysteine-containing subtype,
IPR001395|Aldo/keto reductase
(595 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC007557-1|AAH07557.2| 436|Homo sapiens F-box and leucine-rich ... 281 5e-75
BC031556-1|AAH31556.1| 423|Homo sapiens F-box and leucine-rich ... 278 5e-74
AF186273-1|AAD56248.1| 423|Homo sapiens leucine-rich repeats co... 278 5e-74
CR457121-1|CAG33402.1| 423|Homo sapiens FBXL2 protein. 277 8e-74
AF176518-1|AAF03128.1| 425|Homo sapiens F-box protein FBL2 prot... 277 8e-74
AK001438-1|BAA91691.1| 423|Homo sapiens protein ( Homo sapiens ... 277 1e-73
AF174589-1|AAF04510.1| 423|Homo sapiens F-box protein Fbl2 prot... 272 2e-72
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 248 6e-65
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 248 6e-65
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 248 6e-65
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 248 6e-65
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 248 6e-65
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 248 6e-65
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 248 6e-65
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 248 6e-65
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 228 5e-59
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 226 2e-58
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 226 2e-58
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 226 2e-58
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 226 2e-58
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 226 2e-58
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 226 2e-58
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 226 2e-58
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 226 2e-58
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 226 2e-58
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 226 2e-58
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 226 2e-58
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 226 2e-58
DQ223959-1|ABB03906.1| 404|Homo sapiens F-box and leucine-rich ... 225 3e-58
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 220 1e-56
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 215 3e-55
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 215 3e-55
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 215 3e-55
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 215 3e-55
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 215 3e-55
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 215 3e-55
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 215 3e-55
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 215 4e-55
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 215 4e-55
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 215 4e-55
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 215 4e-55
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 215 5e-55
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 215 5e-55
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 215 5e-55
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 215 5e-55
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 215 5e-55
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 213 1e-54
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 213 1e-54
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 212 3e-54
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 212 3e-54
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 212 3e-54
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 212 3e-54
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 212 3e-54
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 212 3e-54
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 212 3e-54
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 212 3e-54
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 212 3e-54
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 212 3e-54
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 212 3e-54
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 212 3e-54
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 212 3e-54
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 212 3e-54
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 212 3e-54
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 212 3e-54
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 212 3e-54
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 212 3e-54
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 211 5e-54
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 211 5e-54
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 211 5e-54
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 211 6e-54
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 211 6e-54
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 211 6e-54
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 211 6e-54
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 211 6e-54
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 211 6e-54
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 211 6e-54
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 211 6e-54
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 211 6e-54
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 211 6e-54
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 210 1e-53
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 210 1e-53
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 205 3e-52
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 182 2e-45
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 177 7e-44
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 177 7e-44
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 160 1e-38
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 155 6e-37
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 146 3e-34
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 136 2e-31
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 136 2e-31
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 111 9e-24
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 111 9e-24
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 111 9e-24
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 108 6e-23
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 96 3e-19
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 96 3e-19
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 96 3e-19
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 96 4e-19
AL049953-1|CAB43222.1| 250|Homo sapiens hypothetical protein pr... 83 3e-15
BC075061-1|AAH75061.1| 491|Homo sapiens F-box and leucine-rich ... 76 3e-13
AF199356-1|AAF09248.1| 491|Homo sapiens F-box protein FBL6 prot... 76 3e-13
AF174593-1|AAF04514.1| 483|Homo sapiens F-box protein Fbl7 prot... 76 3e-13
AB020647-1|BAA74863.2| 523|Homo sapiens KIAA0840 protein protein. 76 3e-13
BC130566-1|AAI30567.1| 300|Homo sapiens FBXL15 protein protein. 73 2e-12
BC036120-1|AAH36120.1| 296|Homo sapiens FBXL15 protein protein. 73 2e-12
BC002912-1|AAH02912.1| 296|Homo sapiens FBXL15 protein protein. 73 2e-12
AL121928-8|CAI12522.2| 296|Homo sapiens novel protein protein. 73 2e-12
BC028132-1|AAH28132.1| 418|Homo sapiens F-box and leucine-rich ... 73 4e-12
BC126146-1|AAI26147.1| 303|Homo sapiens F-box and leucine-rich ... 72 5e-12
BC126144-1|AAI26145.1| 303|Homo sapiens F-box and leucine-rich ... 72 5e-12
AK126722-1|BAC86658.1| 303|Homo sapiens protein ( Homo sapiens ... 72 5e-12
AY359239-1|AAR13263.1| 690|Homo sapiens F-box and leucine-rich ... 72 7e-12
BC031285-1|AAH31285.1| 707|Homo sapiens FBXL13 protein protein. 71 9e-12
BC026121-1|AAH26121.1| 684|Homo sapiens FBXL13 protein protein. 71 9e-12
AK097537-1|BAC05092.1| 735|Homo sapiens protein ( Homo sapiens ... 71 9e-12
AY359238-1|AAR13262.1| 453|Homo sapiens F-box and leucine-rich ... 71 1e-11
AK095387-1|BAC04540.1| 456|Homo sapiens protein ( Homo sapiens ... 70 3e-11
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 69 5e-11
BC067906-1|AAH67906.1| 213|Homo sapiens antagonist of mitotic e... 67 1e-10
BC045831-1|AAH45831.2| 215|Homo sapiens AMN1 protein protein. 67 1e-10
BC037897-1|AAH37897.3| 215|Homo sapiens AMN1 protein protein. 67 1e-10
AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-relate... 66 4e-10
U33761-1|AAC50242.1| 435|Homo sapiens cyclin A/CDK2-associated ... 64 2e-09
BC007441-1|AAH07441.1| 410|Homo sapiens S-phase kinase-associat... 64 2e-09
BC001441-1|AAH01441.1| 410|Homo sapiens S-phase kinase-associat... 64 2e-09
AY029177-1|AAK31593.1| 424|Homo sapiens F-box protein SKP2 prot... 64 2e-09
AB050981-1|BAB87202.1| 442|Homo sapiens SKP2-like protein type ... 64 2e-09
AB050980-1|BAB87201.1| 410|Homo sapiens SKP2-like protein type ... 64 2e-09
AB050979-1|BAB87200.1| 424|Homo sapiens SKP2-like protein type ... 64 2e-09
BC020575-1|AAH20575.2| 247|Homo sapiens FBXL13 protein protein. 63 2e-09
BC020572-1|AAH20572.2| 569|Homo sapiens FBXL13 protein protein. 63 2e-09
AL121928-7|CAI12520.1| 208|Homo sapiens novel protein protein. 62 5e-09
AL121928-6|CAI12519.1| 203|Homo sapiens novel protein protein. 62 5e-09
AL121928-5|CAI12518.1| 190|Homo sapiens novel protein protein. 62 5e-09
BC091484-1|AAH91484.1| 621|Homo sapiens FBXL4 protein protein. 60 2e-08
BC055010-1|AAH55010.1| 621|Homo sapiens F-box and leucine-rich ... 60 2e-08
BC018785-1|AAH18785.1| 223|Homo sapiens leucine rich repeat con... 60 2e-08
AL022395-1|CAB37981.1| 621|Homo sapiens F-box and leucine-rich ... 60 2e-08
AF199355-1|AAF09247.1| 621|Homo sapiens F-box protein FBL5 prot... 60 2e-08
AF176701-1|AAF03701.1| 313|Homo sapiens F-box protein FBL9 prot... 60 2e-08
AF176699-1|AAF03699.1| 621|Homo sapiens F-box protein FBL4 prot... 60 2e-08
AF174590-1|AAF04511.1| 621|Homo sapiens F-box protein Fbl4 prot... 60 2e-08
AC005250-1|AAP22333.1| 325|Homo sapiens unknown protein. 56 3e-07
Z97653-1|CAJ55832.1| 479|Homo sapiens F-box and leucine-rich re... 56 4e-07
BC036680-1|AAH36680.1| 479|Homo sapiens F-box and leucine-rich ... 56 4e-07
AE006464-13|AAK61245.1| 581|Homo sapiens possible G-protein rec... 56 4e-07
BC008735-1|AAH08735.2| 627|Homo sapiens FBXL10 protein protein. 50 2e-05
AK027692-1|BAB55301.1| 653|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AK027440-1|BAB55112.1| 704|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein. 50 2e-05
AK074718-1|BAC11159.1| 458|Homo sapiens protein ( Homo sapiens ... 49 4e-05
BX537957-1|CAD97924.1| 697|Homo sapiens hypothetical protein pr... 47 2e-04
BC130445-1|AAI30446.1| 843|Homo sapiens F-box protein 11 protein. 47 2e-04
BC043258-1|AAH43258.2| 915|Homo sapiens FBXO11 protein protein. 47 2e-04
AY827075-1|AAV87312.1| 927|Homo sapiens F-box protein 11 protein. 47 2e-04
AK223592-1|BAD97312.1| 843|Homo sapiens F-box only protein 11 i... 47 2e-04
AK000153-1|BAA90978.1| 636|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AF199420-1|AAF09249.1| 690|Homo sapiens F-box protein FBL4 prot... 47 2e-04
AF176700-1|AAF03700.1| 694|Homo sapiens F-box protein FBL5 prot... 47 2e-04
AF174599-1|AAF04520.1| 197|Homo sapiens F-box protein Fbx11 pro... 47 2e-04
AF174591-1|AAF04512.1| 535|Homo sapiens F-box protein Fbl5 prot... 47 2e-04
AF157323-1|AAF67489.1| 674|Homo sapiens p45SKP2-like protein pr... 47 2e-04
AF142481-1|AAF66616.1| 691|Homo sapiens F-box protein FLR1 prot... 47 2e-04
AC114744-1|AAY40929.1| 616|Homo sapiens unknown protein. 47 2e-04
AC079807-1|AAY24083.1| 584|Homo sapiens unknown protein. 47 2e-04
BC037296-1|AAH37296.1| 598|Homo sapiens F-box and WD repeat dom... 46 3e-04
AF176707-1|AAF03129.1| 551|Homo sapiens F-box protein FBX29 pro... 46 3e-04
BC033066-1|AAH33066.1| 539|Homo sapiens F-box and leucine-rich ... 45 9e-04
BC001586-1|AAH01586.1| 326|Homo sapiens F-box and leucine-rich ... 45 9e-04
AK000195-1|BAA91002.1| 326|Homo sapiens protein ( Homo sapiens ... 45 9e-04
AF174592-1|AAF04513.1| 283|Homo sapiens F-box protein Fbl6 prot... 45 9e-04
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 45 9e-04
BC059173-1|AAH59173.1| 524|Homo sapiens F-box and leucine-rich ... 44 0.002
BC030656-1|AAH30656.1| 691|Homo sapiens F-box and leucine-rich ... 44 0.002
U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit... 40 0.019
CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein. 40 0.019
BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated... 40 0.019
BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated... 40 0.019
BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein. 40 0.019
AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated... 40 0.019
AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated... 40 0.019
AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated... 40 0.019
AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated... 40 0.019
AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta ... 40 0.019
AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta ... 40 0.019
BC102028-1|AAI02029.1| 280|Homo sapiens FBXO16 protein protein. 40 0.025
BC102027-1|AAI02028.1| 280|Homo sapiens FBXO16 protein protein. 40 0.025
BC102026-1|AAI02027.1| 292|Homo sapiens F-box protein 16 protein. 40 0.025
BC074986-1|AAH74986.1| 292|Homo sapiens F-box protein 16 protein. 40 0.025
AF453435-1|AAN76812.1| 292|Homo sapiens F-box protein 16 protein. 40 0.025
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 40 0.025
BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat dom... 40 0.033
BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat dom... 40 0.033
BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein. 40 0.033
AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4 prot... 40 0.033
AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7 prot... 40 0.033
AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10 pro... 40 0.033
AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isof... 40 0.033
AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens ... 40 0.033
AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form p... 40 0.033
AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form ... 40 0.033
AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30 pro... 40 0.033
AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isof... 40 0.033
DQ904332-1|ABI98402.1| 155|Homo sapiens F-box only protein 48 p... 39 0.044
BC089423-1|AAH89423.1| 155|Homo sapiens hypothetical protein LO... 39 0.044
AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens ... 39 0.044
AF176706-1|AAF17611.1| 192|Homo sapiens F-box protein FBX11 pro... 39 0.044
AB031230-1|BAA97672.1| 827|Homo sapiens protein containing CXXC... 39 0.058
CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein. 38 0.10
AK223088-1|BAD96808.1| 533|Homo sapiens F-box and leucine-rich ... 38 0.10
AK026541-1|BAB15499.1| 533|Homo sapiens protein ( Homo sapiens ... 38 0.10
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 37 0.18
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 37 0.18
BC099634-1|AAH99634.1| 404|Homo sapiens potassium voltage-gated... 37 0.18
BC096234-1|AAH96234.1| 404|Homo sapiens potassium voltage-gated... 37 0.18
BC096232-1|AAH96232.1| 404|Homo sapiens potassium voltage-gated... 37 0.18
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 37 0.18
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 37 0.18
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 37 0.18
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 37 0.18
AF016411-1|AAB92499.1| 404|Homo sapiens KCNA3.1B protein. 37 0.18
BC125125-1|AAI25126.1| 956|Homo sapiens FBXO10 protein protein. 37 0.23
AL513165-1|CAI16152.1| 954|Homo sapiens F-box protein 10 protein. 37 0.23
AK098777-1|BAC05410.1| 554|Homo sapiens protein ( Homo sapiens ... 37 0.23
AF176705-1|AAF03705.1| 551|Homo sapiens F-box protein FBX10 pro... 37 0.23
AF174598-1|AAF04519.1| 178|Homo sapiens F-box protein Fbx10 pro... 37 0.23
BC101304-1|AAI01305.1| 394|Homo sapiens FBXW12 protein protein. 36 0.41
AY247969-1|AAP75562.1| 464|Homo sapiens putative F-box- and WD4... 36 0.41
AC006477-1|AAS00354.1| 117|Homo sapiens unknown protein. 36 0.54
BC068566-1|AAH68566.1| 555|Homo sapiens F-box protein 33 protein. 35 0.71
BC053537-1|AAH53537.1| 555|Homo sapiens F-box protein 33 protein. 35 0.71
BC012385-1|AAH12385.1| 278|Homo sapiens F-box protein 17 protein. 35 0.71
AK057934-1|BAB71616.1| 287|Homo sapiens protein ( Homo sapiens ... 35 0.71
AF386743-1|AAL37625.1| 278|Homo sapiens F-box protein protein. 35 0.71
BC029579-1|AAH29579.1| 434|Homo sapiens F-box protein 15 protein. 35 0.94
BC014679-1|AAH14679.1| 319|Homo sapiens F-box protein 8 protein. 35 0.94
AY358721-1|AAQ89083.1| 319|Homo sapiens FBXO8 protein. 35 0.94
AF233224-1|AAF67154.1| 319|Homo sapiens F-box protein FBS protein. 35 0.94
AF201932-1|AAF86868.1| 319|Homo sapiens DC10 protein. 35 0.94
AF174596-1|AAF04517.1| 341|Homo sapiens F-box protein Fbx8 prot... 35 0.94
Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats c... 34 1.6
BC063415-1|AAH63415.1| 412|Homo sapiens F-box and WD repeat dom... 34 1.6
BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat ... 34 1.6
AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat... 34 1.6
AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat... 34 1.6
AL627424-2|CAI41027.1| 412|Homo sapiens F-box and WD-40 domain ... 34 1.6
AL627144-3|CAI12232.1| 412|Homo sapiens F-box and WD-40 domain ... 34 1.6
AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat ... 34 1.6
AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat ... 34 1.6
AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat ... 34 1.6
AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat ... 34 1.6
AF281859-1|AAG22739.1| 412|Homo sapiens dactylin protein. 34 1.6
AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A pro... 34 1.6
AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant E3RS-Ika... 34 1.6
BC064360-1|AAH64360.1| 1162|Homo sapiens F-box and leucine-rich ... 33 2.2
BC047371-1|AAH47371.1| 856|Homo sapiens FBXL11 protein protein. 33 2.2
BC003380-1|AAH03380.1| 268|Homo sapiens acidic (leucine-rich) n... 33 2.2
AY057381-1|AAL25814.1| 266|Homo sapiens lecuine-rich acidic pro... 33 2.2
AL138795-4|CAI22808.1| 268|Homo sapiens acidic (leucine-rich) n... 33 2.2
AL138795-1|CAI22806.1| 220|Homo sapiens acidic (leucine-rich) n... 33 2.2
AK223469-1|BAD97189.1| 266|Homo sapiens acidic (leucine-rich) n... 33 2.2
AK095228-1|BAC04505.1| 218|Homo sapiens protein ( Homo sapiens ... 33 2.2
AK092672-1|BAC03942.1| 268|Homo sapiens mRNA. protein. 33 2.2
AK024505-1|BAB15795.1| 757|Homo sapiens FLJ00115 protein protein. 33 2.2
AF179221-1|AAD56012.1| 474|Homo sapiens F-box protein Lilina pr... 33 2.2
AB023221-1|BAA76848.2| 1163|Homo sapiens KIAA1004 protein protein. 33 2.2
BC033935-1|AAH33935.1| 188|Homo sapiens F-box protein 36 protein. 33 3.8
BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat dom... 33 3.8
BC022538-1|AAH22538.1| 157|Homo sapiens FBXO36 protein protein. 33 3.8
AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b pro... 33 3.8
AC009973-2|AAY14756.1| 188|Homo sapiens unknown protein. 33 3.8
AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats pr... 33 3.8
AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats pr... 33 3.8
AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats pr... 33 3.8
AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein. 33 3.8
X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 32 6.6
X04657-1|CAA28355.1| 110|Homo sapiens villin C-terminus protein. 32 6.6
U07000-4|AAB60391.1| 278|Homo sapiens unknown protein. 32 6.6
AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 32 6.6
AK024483-1|BAB15773.1| 278|Homo sapiens FLJ00077 protein protein. 32 6.6
AF174606-1|AAF04527.1| 406|Homo sapiens F-box protein Fbw3 prot... 32 6.6
BC110334-1|AAI10335.1| 454|Homo sapiens F-box and WD repeat dom... 31 8.7
BC037552-1|AAH37552.1| 372|Homo sapiens protein phosphatase 1K ... 31 8.7
BC018738-1|AAH18738.1| 454|Homo sapiens F-box and WD repeat dom... 31 8.7
AL161911-2|CAI95113.1| 454|Homo sapiens F-box and WD-40 domain ... 31 8.7
AK022484-1|BAB14051.1| 454|Homo sapiens protein ( Homo sapiens ... 31 8.7
AF193594-1|AAP97280.1| 357|Homo sapiens MD6b protein. 31 8.7
AF176698-1|AAF13226.1| 422|Homo sapiens F-box protein FBW2 prot... 31 8.7
AF145024-1|AAP97276.1| 422|Homo sapiens MD6 protein protein. 31 8.7
AF129531-1|AAF04465.1| 422|Homo sapiens F-box protein Fbw2 prot... 31 8.7
>BC007557-1|AAH07557.2| 436|Homo sapiens F-box and leucine-rich
repeat protein 20 protein.
Length = 436
Score = 281 bits (689), Expect = 5e-75
Identities = 122/189 (64%), Positives = 156/189 (82%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
F+N DE IN+KLPKELLLRI S+LDVV+LCRCAQVS+ WN+LALDGSNWQRIDLF+FQR
Sbjct: 16 FSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQR 75
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
D+EG V+ENIS+RCGGFLR+LSLRGC +GD +++T AQ+C NIE LNLN C K TD TC
Sbjct: 76 DIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATC 135
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
+L + CSKL+ ++L SC S++++SLKAL++GCPLL +N+SWC +T+ G++AL RGC
Sbjct: 136 TSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCG 195
Query: 547 KLKSFICKG 555
LK+ KG
Sbjct: 196 GLKALFLKG 204
Score = 91.9 bits (218), Expect = 6e-18
Identities = 56/186 (30%), Positives = 89/186 (47%), Gaps = 5/186 (2%)
Query: 372 ENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQ--RDVE 429
+ I ++ + + R +L +SL C V N L N + I++
Sbjct: 74 QRDIEGRVVENISKRCGGFLRKLSLRGCLGVGD--NALRTFAQNCRNIEVLNLNGCTKTT 131
Query: 430 GPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
++S+ C LR L L C SI + S+K L++ CP +E LN++ C ++T QAL
Sbjct: 132 DATCTSLSKFCSK-LRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQAL 190
Query: 490 GRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
R C L+ + L C + D +LK + CP L +N+ C IT+ G+ + RGC KL+
Sbjct: 191 VRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQ 250
Query: 550 SFICKG 555
S G
Sbjct: 251 SLCASG 256
Score = 88.6 bits (210), Expect = 5e-17
Identities = 42/117 (35%), Positives = 65/117 (55%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
I+ + + CGG L+ L L+GC + D ++K + CP + LNL C +ITD+ + R
Sbjct: 187 IQALVRGCGG-LKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRG 245
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C KLQ + C +++D L AL CP L + V+ C +T+ G LAR C +L+
Sbjct: 246 CHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELE 302
Score = 78.6 bits (185), Expect = 6e-14
Identities = 34/101 (33%), Positives = 58/101 (57%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+ L GC +I D + L Q+CP + L + +C ++TD L R C +L+K++L+
Sbjct: 249 LQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEE 308
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARG 544
C ++D +L L+ CP L +++S C+ IT+ G+ L G
Sbjct: 309 CVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNG 349
Score = 72.1 bits (169), Expect = 5e-12
Identities = 32/117 (27%), Positives = 64/117 (54%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
++ +S+ C L QL++ C+ + ++ L + C ++ L L C ++ D+ + +G
Sbjct: 161 LKALSEGCP-LLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAH 219
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +L +NL +C ++D L + GC L + S C +IT++ + AL + CP+L+
Sbjct: 220 CPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLR 276
Score = 69.7 bits (163), Expect = 3e-11
Identities = 49/162 (30%), Positives = 82/162 (50%), Gaps = 11/162 (6%)
Query: 395 SLCR--CAQVSKLWNILALDGSNWQRIDLFEFQR--DVEGPVIENISQRCGGFLRQLSLR 450
SLC C+ ++ IL G N R+ + E R + +++ C L ++ L
Sbjct: 251 SLCASGCSNITDA--ILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHE-LEKMDLE 307
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGR-RCS--KLQKINLDSCPSV 507
C I D ++ L+ CP ++ L+L+ C+ ITD + LG C+ +L+ I LD+CP +
Sbjct: 308 ECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLI 367
Query: 508 SDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+D SL+ L C L + + CQ IT +G++ L P +K
Sbjct: 368 TDASLEHL-KSCHSLERIELYDCQQITRAGIKRLRTHLPNIK 408
Score = 68.5 bits (160), Expect = 6e-11
Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 1/159 (0%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLR 450
L+ +++ C QV+K + G + + +E ++ I C + L+L+
Sbjct: 171 LEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVT-LNLQ 229
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDI 510
C I D + T+ + C ++ L + C ITD ALG+ C +L+ + + C ++D+
Sbjct: 230 TCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDV 289
Query: 511 SLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
LA C L +++ C IT+S + L+ CP+L+
Sbjct: 290 GFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQ 328
>BC031556-1|AAH31556.1| 423|Homo sapiens F-box and leucine-rich
repeat protein 2 protein.
Length = 423
Score = 278 bits (681), Expect = 5e-74
Identities = 123/189 (65%), Positives = 153/189 (80%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
F+N DE IN+KLPKELLLRI S+LD+V+LCRCAQ+SK WNILALDGSNWQRIDLF FQ
Sbjct: 3 FSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQT 62
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
DVEG V+ENIS+RCGGFLR+LSLRGC +GD S+KT AQ+C NIE LNLN C KITD TC
Sbjct: 63 DVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTC 122
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
+L R CSKL+ ++L SC S+++ SLK +++GC L ++N+SWC IT+ G+EAL RGC
Sbjct: 123 YSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 182
Query: 547 KLKSFICKG 555
LK+ + +G
Sbjct: 183 GLKALLLRG 191
Score = 84.6 bits (200), Expect = 9e-16
Identities = 42/117 (35%), Positives = 65/117 (55%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
IE + + C G L+ L LRGC + D ++K + C + LNL C +ITD+ + R
Sbjct: 174 IEALVRGCRG-LKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRG 232
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +LQ + L C +++D SL AL CP L + + C +T++G LAR C +L+
Sbjct: 233 CHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELE 289
Score = 82.6 bits (195), Expect = 4e-15
Identities = 42/121 (34%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Query: 435 NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCS 494
++S+ C L+ L L C SI + S+K +++ C N+E LNL+ C +IT +AL R C
Sbjct: 124 SLSRFCSK-LKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 182
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICK 554
L+ + L C + D +LK + + C L +N+ C IT+ GV + RGC +L++
Sbjct: 183 GLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLS 242
Query: 555 G 555
G
Sbjct: 243 G 243
Score = 76.2 bits (179), Expect = 3e-13
Identities = 36/107 (33%), Positives = 61/107 (57%), Gaps = 2/107 (1%)
Query: 434 ENISQRCGGF--LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E + Q C G L+ L L GC ++ D S+ L +CP ++ L +C +TD L R
Sbjct: 224 EGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLAR 283
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGV 538
C +L+K++L+ C ++D +L L+ CP L +++S C+ IT+ G+
Sbjct: 284 NCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI 330
Score = 69.3 bits (162), Expect = 4e-11
Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLR 450
L+ ++L C Q++K + G + L +E +++I C + L+L+
Sbjct: 158 LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELV-SLNLQ 216
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDI 510
C I D + + + C ++ L L+ C +TD + ALG C +LQ + C ++D
Sbjct: 217 SCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDA 276
Query: 511 SLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
LA C L +++ C IT+S + L+ CPKL++
Sbjct: 277 GFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQA 316
Score = 68.5 bits (160), Expect = 6e-11
Identities = 32/117 (27%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
++ IS+ C L L+L C+ I ++ L + C ++ L L C ++ D+ + +
Sbjct: 148 LKGISEGCRN-LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNY 206
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +L +NL SC ++D + + GC L + +S C ++T++ + AL CP+L+
Sbjct: 207 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQ 263
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+ L C + D LA++C +E ++L +C ITD T L C KLQ ++L
Sbjct: 262 LQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSH 321
Query: 504 CPSVSDISLKALAD---GCPLLTHVNVSWCQSITESGVEAL--ARGCPKLKSFICKGKPR 558
C ++D + L++ G L + + C IT+ +E L RG +L+ + C+ R
Sbjct: 322 CELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTR 381
Query: 559 ESVPRLR 565
+ R+R
Sbjct: 382 AGIKRMR 388
Score = 56.4 bits (130), Expect = 3e-07
Identities = 42/164 (25%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR--DVEGPVIENISQRCGGFLRQLS 448
L + L C+ ++ ++ AL G N R+ + E R + +++ C L ++
Sbjct: 236 LQALCLSGCSNLTDA-SLTAL-GLNCPRLQILEAARCSHLTDAGFTLLARNCHE-LEKMD 292
Query: 449 LRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR-CS--KLQKINLDSCP 505
L C I D ++ L+ CP ++ L+L+ C+ ITD L C +L+ + LD+C
Sbjct: 293 LEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCL 352
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
++D++L+ L + C L + + CQ +T +G++ + P +K
Sbjct: 353 LITDVALEHL-ENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395
>AF186273-1|AAD56248.1| 423|Homo sapiens leucine-rich repeats
containing F-box protein FBL3 protein.
Length = 423
Score = 278 bits (681), Expect = 5e-74
Identities = 123/189 (65%), Positives = 153/189 (80%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
F+N DE IN+KLPKELLLRI S+LD+V+LCRCAQ+SK WNILALDGSNWQRIDLF FQ
Sbjct: 3 FSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQT 62
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
DVEG V+ENIS+RCGGFLR+LSLRGC +GD S+KT AQ+C NIE LNLN C KITD TC
Sbjct: 63 DVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTC 122
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
+L R CSKL+ ++L SC S+++ SLK +++GC L ++N+SWC IT+ G+EAL RGC
Sbjct: 123 YSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 182
Query: 547 KLKSFICKG 555
LK+ + +G
Sbjct: 183 GLKALLLRG 191
Score = 84.6 bits (200), Expect = 9e-16
Identities = 42/117 (35%), Positives = 65/117 (55%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
IE + + C G L+ L LRGC + D ++K + C + LNL C +ITD+ + R
Sbjct: 174 IEALVRGCRG-LKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRG 232
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +LQ + L C +++D SL AL CP L + + C +T++G LAR C +L+
Sbjct: 233 CHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELE 289
Score = 82.6 bits (195), Expect = 4e-15
Identities = 42/121 (34%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Query: 435 NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCS 494
++S+ C L+ L L C SI + S+K +++ C N+E LNL+ C +IT +AL R C
Sbjct: 124 SLSRFCSK-LKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 182
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICK 554
L+ + L C + D +LK + + C L +N+ C IT+ GV + RGC +L++
Sbjct: 183 GLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLS 242
Query: 555 G 555
G
Sbjct: 243 G 243
Score = 76.2 bits (179), Expect = 3e-13
Identities = 36/107 (33%), Positives = 61/107 (57%), Gaps = 2/107 (1%)
Query: 434 ENISQRCGGF--LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E + Q C G L+ L L GC ++ D S+ L +CP ++ L +C +TD L R
Sbjct: 224 EGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLAR 283
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGV 538
C +L+K++L+ C ++D +L L+ CP L +++S C+ IT+ G+
Sbjct: 284 NCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI 330
Score = 69.3 bits (162), Expect = 4e-11
Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLR 450
L+ ++L C Q++K + G + L +E +++I C + L+L+
Sbjct: 158 LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELV-SLNLQ 216
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDI 510
C I D + + + C ++ L L+ C +TD + ALG C +LQ + C ++D
Sbjct: 217 SCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDA 276
Query: 511 SLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
LA C L +++ C IT+S + L+ CPKL++
Sbjct: 277 GFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQA 316
Score = 68.5 bits (160), Expect = 6e-11
Identities = 32/117 (27%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
++ IS+ C L L+L C+ I ++ L + C ++ L L C ++ D+ + +
Sbjct: 148 LKGISEGCRN-LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNY 206
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +L +NL SC ++D + + GC L + +S C ++T++ + AL CP+L+
Sbjct: 207 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQ 263
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+ L C + D LA++C +E ++L +C ITD T L C KLQ ++L
Sbjct: 262 LQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSH 321
Query: 504 CPSVSDISLKALAD---GCPLLTHVNVSWCQSITESGVEAL--ARGCPKLKSFICKGKPR 558
C ++D + L++ G L + + C IT+ +E L RG +L+ + C+ R
Sbjct: 322 CELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTR 381
Query: 559 ESVPRLR 565
+ R+R
Sbjct: 382 AGIKRMR 388
Score = 56.4 bits (130), Expect = 3e-07
Identities = 42/164 (25%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR--DVEGPVIENISQRCGGFLRQLS 448
L + L C+ ++ ++ AL G N R+ + E R + +++ C L ++
Sbjct: 236 LQALCLSGCSNLTDA-SLTAL-GLNCPRLQILEAARCSHLTDAGFTLLARNCHE-LEKMD 292
Query: 449 LRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR-CS--KLQKINLDSCP 505
L C I D ++ L+ CP ++ L+L+ C+ ITD L C +L+ + LD+C
Sbjct: 293 LEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCL 352
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
++D++L+ L + C L + + CQ +T +G++ + P +K
Sbjct: 353 LITDVALEHL-ENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395
>CR457121-1|CAG33402.1| 423|Homo sapiens FBXL2 protein.
Length = 423
Score = 277 bits (679), Expect = 8e-74
Identities = 123/189 (65%), Positives = 153/189 (80%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
F+N DE IN+KLPKELLLRI S+LD+V+LCRCAQ+SK WNILALDGSNWQRIDLF FQ
Sbjct: 3 FSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQI 62
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
DVEG V+ENIS+RCGGFLR+LSLRGC +GD S+KT AQ+C NIE LNLN C KITD TC
Sbjct: 63 DVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTC 122
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
+L R CSKL+ ++L SC S+++ SLK +++GC L ++N+SWC IT+ G+EAL RGC
Sbjct: 123 YSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 182
Query: 547 KLKSFICKG 555
LK+ + +G
Sbjct: 183 GLKALLLRG 191
Score = 84.6 bits (200), Expect = 9e-16
Identities = 42/117 (35%), Positives = 65/117 (55%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
IE + + C G L+ L LRGC + D ++K + C + LNL C +ITD+ + R
Sbjct: 174 IEALVRGCRG-LKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRG 232
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +LQ + L C +++D SL AL CP L + + C +T++G LAR C +L+
Sbjct: 233 CHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELE 289
Score = 82.6 bits (195), Expect = 4e-15
Identities = 42/121 (34%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Query: 435 NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCS 494
++S+ C L+ L L C SI + S+K +++ C N+E LNL+ C +IT +AL R C
Sbjct: 124 SLSRFCSK-LKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 182
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICK 554
L+ + L C + D +LK + + C L +N+ C IT+ GV + RGC +L++
Sbjct: 183 GLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLS 242
Query: 555 G 555
G
Sbjct: 243 G 243
Score = 76.2 bits (179), Expect = 3e-13
Identities = 36/107 (33%), Positives = 61/107 (57%), Gaps = 2/107 (1%)
Query: 434 ENISQRCGGF--LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E + Q C G L+ L L GC ++ D S+ L +CP ++ L +C +TD L R
Sbjct: 224 EGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLAR 283
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGV 538
C +L+K++L+ C ++D +L L+ CP L +++S C+ IT+ G+
Sbjct: 284 NCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI 330
Score = 69.3 bits (162), Expect = 4e-11
Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLR 450
L+ ++L C Q++K + G + L +E +++I C + L+L+
Sbjct: 158 LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELV-SLNLQ 216
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDI 510
C I D + + + C ++ L L+ C +TD + ALG C +LQ + C ++D
Sbjct: 217 SCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDA 276
Query: 511 SLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
LA C L +++ C IT+S + L+ CPKL++
Sbjct: 277 GFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQA 316
Score = 68.5 bits (160), Expect = 6e-11
Identities = 32/117 (27%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
++ IS+ C L L+L C+ I ++ L + C ++ L L C ++ D+ + +
Sbjct: 148 LKGISEGCRN-LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNY 206
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +L +NL SC ++D + + GC L + +S C ++T++ + AL CP+L+
Sbjct: 207 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQ 263
Score = 58.8 bits (136), Expect = 5e-08
Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+ L C + D LA++C +E ++L +C ITD T L C KLQ ++L
Sbjct: 262 LQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSH 321
Query: 504 CPSVSDISLKALAD---GCPLLTHVNVSWCQSITESGVEAL--ARGCPKLKSFICKGKPR 558
C ++D + L++ G L + + C IT+ +E L RG +L+ + C+ R
Sbjct: 322 CELITDDGILHLSNSTCGHEGLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTR 381
Query: 559 ESVPRLR 565
+ R+R
Sbjct: 382 AGIKRMR 388
Score = 55.2 bits (127), Expect = 6e-07
Identities = 42/164 (25%), Positives = 81/164 (49%), Gaps = 9/164 (5%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR--DVEGPVIENISQRCGGFLRQLS 448
L + L C+ ++ ++ AL G N R+ + E R + +++ C L ++
Sbjct: 236 LQALCLSGCSNLTDA-SLTAL-GLNCPRLQILEAARCSHLTDAGFTLLARNCHE-LEKMD 292
Query: 449 LRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR-CSK--LQKINLDSCP 505
L C I D ++ L+ CP ++ L+L+ C+ ITD L C L+ + LD+C
Sbjct: 293 LEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHEGLRVLELDNCL 352
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
++D++L+ L + C L + + CQ +T +G++ + P +K
Sbjct: 353 LITDVALEHL-ENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395
>AF176518-1|AAF03128.1| 425|Homo sapiens F-box protein FBL2
protein.
Length = 425
Score = 277 bits (679), Expect = 8e-74
Identities = 123/189 (65%), Positives = 153/189 (80%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
F+N DE IN+KLPKELLLRI S+LD+V+LCRCAQ+SK WNILALDGSNWQRIDLF FQ
Sbjct: 5 FSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQI 64
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
DVEG V+ENIS+RCGGFLR+LSLRGC +GD S+KT AQ+C NIE LNLN C KITD TC
Sbjct: 65 DVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTC 124
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
+L R CSKL+ ++L SC S+++ SLK +++GC L ++N+SWC IT+ G+EAL RGC
Sbjct: 125 YSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 184
Query: 547 KLKSFICKG 555
LK+ + +G
Sbjct: 185 GLKALLLRG 193
Score = 84.6 bits (200), Expect = 9e-16
Identities = 42/117 (35%), Positives = 65/117 (55%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
IE + + C G L+ L LRGC + D ++K + C + LNL C +ITD+ + R
Sbjct: 176 IEALVRGCRG-LKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRG 234
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +LQ + L C +++D SL AL CP L + + C +T++G LAR C +L+
Sbjct: 235 CHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELE 291
Score = 82.6 bits (195), Expect = 4e-15
Identities = 42/121 (34%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Query: 435 NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCS 494
++S+ C L+ L L C SI + S+K +++ C N+E LNL+ C +IT +AL R C
Sbjct: 126 SLSRFCSK-LKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 184
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICK 554
L+ + L C + D +LK + + C L +N+ C IT+ GV + RGC +L++
Sbjct: 185 GLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLS 244
Query: 555 G 555
G
Sbjct: 245 G 245
Score = 76.2 bits (179), Expect = 3e-13
Identities = 36/107 (33%), Positives = 61/107 (57%), Gaps = 2/107 (1%)
Query: 434 ENISQRCGGF--LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E + Q C G L+ L L GC ++ D S+ L +CP ++ L +C +TD L R
Sbjct: 226 EGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLAR 285
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGV 538
C +L+K++L+ C ++D +L L+ CP L +++S C+ IT+ G+
Sbjct: 286 NCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI 332
Score = 69.3 bits (162), Expect = 4e-11
Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLR 450
L+ ++L C Q++K + G + L +E +++I C + L+L+
Sbjct: 160 LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELV-SLNLQ 218
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDI 510
C I D + + + C ++ L L+ C +TD + ALG C +LQ + C ++D
Sbjct: 219 SCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDA 278
Query: 511 SLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
LA C L +++ C IT+S + L+ CPKL++
Sbjct: 279 GFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQA 318
Score = 68.5 bits (160), Expect = 6e-11
Identities = 32/117 (27%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
++ IS+ C L L+L C+ I ++ L + C ++ L L C ++ D+ + +
Sbjct: 150 LKGISEGCRN-LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNY 208
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +L +NL SC ++D + + GC L + +S C ++T++ + AL CP+L+
Sbjct: 209 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQ 265
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+ L C + D LA++C +E ++L +C ITD T L C KLQ ++L
Sbjct: 264 LQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSH 323
Query: 504 CPSVSDISLKALAD---GCPLLTHVNVSWCQSITESGVEAL--ARGCPKLKSFICKGKPR 558
C ++D + L++ G L + + C IT+ +E L RG +L+ + C+ R
Sbjct: 324 CELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTR 383
Query: 559 ESVPRLR 565
+ R+R
Sbjct: 384 AGIKRMR 390
Score = 56.4 bits (130), Expect = 3e-07
Identities = 42/164 (25%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR--DVEGPVIENISQRCGGFLRQLS 448
L + L C+ ++ ++ AL G N R+ + E R + +++ C L ++
Sbjct: 238 LQALCLSGCSNLTDA-SLTAL-GLNCPRLQILEAARCSHLTDAGFTLLARNCHE-LEKMD 294
Query: 449 LRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR-CS--KLQKINLDSCP 505
L C I D ++ L+ CP ++ L+L+ C+ ITD L C +L+ + LD+C
Sbjct: 295 LEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCL 354
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
++D++L+ L + C L + + CQ +T +G++ + P +K
Sbjct: 355 LITDVALEHL-ENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 397
>AK001438-1|BAA91691.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ10576 fis, clone NT2RP2003329, weakly similar to
PUTATIVE ADENYLATE CYCLASE REGULATORY PROTEIN. ).
Length = 423
Score = 277 bits (678), Expect = 1e-73
Identities = 122/189 (64%), Positives = 153/189 (80%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
F+N DE IN+KLPKELLLRI S+LD+V+LCRCAQ+SK WNILALDGSNWQRIDLF FQ
Sbjct: 3 FSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQT 62
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
DVEG V+ENIS+RCGGFL++LSLRGC +GD S+KT AQ+C NIE LNLN C KITD TC
Sbjct: 63 DVEGRVVENISKRCGGFLKKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTC 122
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
+L R CSKL+ ++L SC S+++ SLK +++GC L ++N+SWC IT+ G+EAL RGC
Sbjct: 123 YSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 182
Query: 547 KLKSFICKG 555
LK+ + +G
Sbjct: 183 GLKALLLRG 191
Score = 84.6 bits (200), Expect = 9e-16
Identities = 42/117 (35%), Positives = 65/117 (55%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
IE + + C G L+ L LRGC + D ++K + C + LNL C +ITD+ + R
Sbjct: 174 IEALVRGCRG-LKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRG 232
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +LQ + L C +++D SL AL CP L + + C +T++G LAR C +L+
Sbjct: 233 CHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELE 289
Score = 82.6 bits (195), Expect = 4e-15
Identities = 42/121 (34%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Query: 435 NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCS 494
++S+ C L+ L L C SI + S+K +++ C N+E LNL+ C +IT +AL R C
Sbjct: 124 SLSRFCSK-LKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 182
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICK 554
L+ + L C + D +LK + + C L +N+ C IT+ GV + RGC +L++
Sbjct: 183 GLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLS 242
Query: 555 G 555
G
Sbjct: 243 G 243
Score = 76.2 bits (179), Expect = 3e-13
Identities = 36/107 (33%), Positives = 61/107 (57%), Gaps = 2/107 (1%)
Query: 434 ENISQRCGGF--LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E + Q C G L+ L L GC ++ D S+ L +CP ++ L +C +TD L R
Sbjct: 224 EGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLAR 283
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGV 538
C +L+K++L+ C ++D +L L+ CP L +++S C+ IT+ G+
Sbjct: 284 NCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI 330
Score = 69.3 bits (162), Expect = 4e-11
Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLR 450
L+ ++L C Q++K + G + L +E +++I C + L+L+
Sbjct: 158 LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELV-SLNLQ 216
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDI 510
C I D + + + C ++ L L+ C +TD + ALG C +LQ + C ++D
Sbjct: 217 SCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDA 276
Query: 511 SLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
LA C L +++ C IT+S + L+ CPKL++
Sbjct: 277 GFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQA 316
Score = 68.5 bits (160), Expect = 6e-11
Identities = 32/117 (27%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
++ IS+ C L L+L C+ I ++ L + C ++ L L C ++ D+ + +
Sbjct: 148 LKGISEGCRN-LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNY 206
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +L +NL SC ++D + + GC L + +S C ++T++ + AL CP+L+
Sbjct: 207 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQ 263
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+ L C + D LA++C +E ++L +C ITD T L C KLQ ++L
Sbjct: 262 LQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSH 321
Query: 504 CPSVSDISLKALAD---GCPLLTHVNVSWCQSITESGVEAL--ARGCPKLKSFICKGKPR 558
C ++D + L++ G L + + C IT+ +E L RG +L+ + C+ R
Sbjct: 322 CELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTR 381
Query: 559 ESVPRLR 565
+ R+R
Sbjct: 382 AGIKRMR 388
Score = 56.4 bits (130), Expect = 3e-07
Identities = 42/164 (25%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR--DVEGPVIENISQRCGGFLRQLS 448
L + L C+ ++ ++ AL G N R+ + E R + +++ C L ++
Sbjct: 236 LQALCLSGCSNLTDA-SLTAL-GLNCPRLQILEAARCSHLTDAGFTLLARNCHE-LEKMD 292
Query: 449 LRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR-CS--KLQKINLDSCP 505
L C I D ++ L+ CP ++ L+L+ C+ ITD L C +L+ + LD+C
Sbjct: 293 LEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCL 352
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
++D++L+ L + C L + + CQ +T +G++ + P +K
Sbjct: 353 LITDVALEHL-ENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395
>AF174589-1|AAF04510.1| 423|Homo sapiens F-box protein Fbl2
protein.
Length = 423
Score = 272 bits (668), Expect = 2e-72
Identities = 122/189 (64%), Positives = 151/189 (79%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
F+N DE IN+KLPKELLLRI S+LD+V+LCRCAQ+SK WNILALDGSNWQRIDLF FQ
Sbjct: 3 FSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQI 62
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
DVEG V+ENIS+RC GFLR+LSLRGC +GD S+KT AQ+C NIE LNLN C KITD TC
Sbjct: 63 DVEGRVVENISKRCVGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTC 122
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
+L R CSKL+ + L SC S+++ SLK +++GC L ++N+SWC IT+ G+EAL RGC
Sbjct: 123 YSLSRFCSKLKHLXLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 182
Query: 547 KLKSFICKG 555
LK+ + +G
Sbjct: 183 GLKALLLRG 191
Score = 84.6 bits (200), Expect = 9e-16
Identities = 42/117 (35%), Positives = 65/117 (55%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
IE + + C G L+ L LRGC + D ++K + C + LNL C +ITD+ + R
Sbjct: 174 IEALVRGCRG-LKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRG 232
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +LQ + L C +++D SL AL CP L + + C +T++G LAR C +L+
Sbjct: 233 CHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELE 289
Score = 82.6 bits (195), Expect = 4e-15
Identities = 42/121 (34%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Query: 435 NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCS 494
++S+ C L+ L L C SI + S+K +++ C N+E LNL+ C +IT +AL R C
Sbjct: 124 SLSRFCSK-LKHLXLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCR 182
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICK 554
L+ + L C + D +LK + + C L +N+ C IT+ GV + RGC +L++
Sbjct: 183 GLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLS 242
Query: 555 G 555
G
Sbjct: 243 G 243
Score = 74.1 bits (174), Expect = 1e-12
Identities = 35/107 (32%), Positives = 60/107 (56%), Gaps = 2/107 (1%)
Query: 434 ENISQRCGGF--LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E + Q C G L+ L L GC ++ D S+ L +CP ++ L +C +TD L R
Sbjct: 224 EGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLAR 283
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGV 538
C +L+K++L+ C ++D +L L+ CP L +++S C+ I + G+
Sbjct: 284 NCHELEKMDLEXCILITDSTLIQLSIHCPKLQALSLSHCELIXDDGI 330
Score = 69.7 bits (163), Expect = 3e-11
Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLR 450
L+ ++L C Q++K + G + L +E +++I C + L+L+
Sbjct: 158 LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELV-SLNLQ 216
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDI 510
C I D + + + C ++ L L+ C +TD + ALG C +LQ + C ++D
Sbjct: 217 SCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDA 276
Query: 511 SLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
LA C L +++ C IT+S + L+ CPKL++
Sbjct: 277 GFTLLARNCHELEKMDLEXCILITDSTLIQLSIHCPKLQA 316
Score = 68.5 bits (160), Expect = 6e-11
Identities = 32/117 (27%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
++ IS+ C L L+L C+ I ++ L + C ++ L L C ++ D+ + +
Sbjct: 148 LKGISEGCRN-LEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNY 206
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +L +NL SC ++D + + GC L + +S C ++T++ + AL CP+L+
Sbjct: 207 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQ 263
Score = 56.0 bits (129), Expect = 4e-07
Identities = 36/127 (28%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+ L C + D LA++C +E ++L C ITD T L C KLQ ++L
Sbjct: 262 LQILEAARCSHLTDAGFTLLARNCHELEKMDLEXCILITDSTLIQLSIHCPKLQALSLSH 321
Query: 504 CPSVSDISLKALAD---GCPLLTHVNVSWCQSITESGVEAL--ARGCPKLKSFICKGKPR 558
C + D + L++ G L + + C IT+ + L RG +L+ + C+ R
Sbjct: 322 CELIXDDGILHLSNSTCGHERLRVLELDNCLLITDVALXHLENCRGLERLELYDCQQVTR 381
Query: 559 ESVPRLR 565
+ R+R
Sbjct: 382 AGIKRMR 388
Score = 54.0 bits (124), Expect = 1e-06
Identities = 41/164 (25%), Positives = 80/164 (48%), Gaps = 9/164 (5%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR--DVEGPVIENISQRCGGFLRQLS 448
L + L C+ ++ ++ AL G N R+ + E R + +++ C L ++
Sbjct: 236 LQALCLSGCSNLTDA-SLTAL-GLNCPRLQILEAARCSHLTDAGFTLLARNCHE-LEKMD 292
Query: 449 LRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR-CS--KLQKINLDSCP 505
L C I D ++ L+ CP ++ L+L+ C+ I D L C +L+ + LD+C
Sbjct: 293 LEXCILITDSTLIQLSIHCPKLQALSLSHCELIXDDGILHLSNSTCGHERLRVLELDNCL 352
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
++D++L L + C L + + CQ +T +G++ + P +K
Sbjct: 353 LITDVALXHL-ENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 248 bits (606), Expect = 6e-65
Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 21/312 (6%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VV 119
GQ+ L G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V
Sbjct: 11 GQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAV 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD 170
RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD
Sbjct: 71 PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNAD 130
Query: 171 YS--HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ + + ETW+ LE G+V+ +GLSNFN +Q++ +L +++P +Q+E H
Sbjct: 131 GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPY 190
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL 288
Q E++ CQ+ G+ V YSP GS E +++PV+ ++A+KYG++ QI+L
Sbjct: 191 LAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILL 250
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW------ 342
RWQ++RKV+ IPK++ P R+ +NI +FDFT +P+E++++N + + RY +P
Sbjct: 251 RWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRV 310
Query: 343 ---QNHPYYPFD 351
HP YPF+
Sbjct: 311 PRDAGHPLYPFN 322
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 248 bits (606), Expect = 6e-65
Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 21/312 (6%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VV 119
GQ+ L G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V
Sbjct: 11 GQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAV 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD 170
RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD
Sbjct: 71 PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNAD 130
Query: 171 YS--HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ + + ETW+ LE G+V+ +GLSNFN +Q++ +L +++P +Q+E H
Sbjct: 131 GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPY 190
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL 288
Q E++ CQ+ G+ V YSP GS E +++PV+ ++A+KYG++ QI+L
Sbjct: 191 LAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILL 250
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW------ 342
RWQ++RKV+ IPK++ P R+ +NI +FDFT +P+E++++N + + RY +P
Sbjct: 251 RWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRV 310
Query: 343 ---QNHPYYPFD 351
HP YPF+
Sbjct: 311 PRDAGHPLYPFN 322
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 248 bits (606), Expect = 6e-65
Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 21/312 (6%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VV 119
GQ+ L G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V
Sbjct: 11 GQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAV 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD 170
RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD
Sbjct: 71 PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNAD 130
Query: 171 YS--HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ + + ETW+ LE G+V+ +GLSNFN +Q++ +L +++P +Q+E H
Sbjct: 131 GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPY 190
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL 288
Q E++ CQ+ G+ V YSP GS E +++PV+ ++A+KYG++ QI+L
Sbjct: 191 LAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILL 250
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW------ 342
RWQ++RKV+ IPK++ P R+ +NI +FDFT +P+E++++N + + RY +P
Sbjct: 251 RWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRV 310
Query: 343 ---QNHPYYPFD 351
HP YPF+
Sbjct: 311 PRDAGHPLYPFN 322
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 248 bits (606), Expect = 6e-65
Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 21/312 (6%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VV 119
GQ+ L G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V
Sbjct: 11 GQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAV 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD 170
RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD
Sbjct: 71 PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNAD 130
Query: 171 YS--HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ + + ETW+ LE G+V+ +GLSNFN +Q++ +L +++P +Q+E H
Sbjct: 131 GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPY 190
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL 288
Q E++ CQ+ G+ V YSP GS E +++PV+ ++A+KYG++ QI+L
Sbjct: 191 LAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILL 250
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW------ 342
RWQ++RKV+ IPK++ P R+ +NI +FDFT +P+E++++N + + RY +P
Sbjct: 251 RWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRV 310
Query: 343 ---QNHPYYPFD 351
HP YPF+
Sbjct: 311 PRDAGHPLYPFN 322
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 248 bits (606), Expect = 6e-65
Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 21/312 (6%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VV 119
GQ+ L G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V
Sbjct: 11 GQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAV 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD 170
RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD
Sbjct: 71 PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNAD 130
Query: 171 YS--HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ + + ETW+ LE G+V+ +GLSNFN +Q++ +L +++P +Q+E H
Sbjct: 131 GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPY 190
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL 288
Q E++ CQ+ G+ V YSP GS E +++PV+ ++A+KYG++ QI+L
Sbjct: 191 LAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILL 250
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW------ 342
RWQ++RKV+ IPK++ P R+ +NI +FDFT +P+E++++N + + RY +P
Sbjct: 251 RWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRV 310
Query: 343 ---QNHPYYPFD 351
HP YPF+
Sbjct: 311 PRDAGHPLYPFN 322
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 248 bits (606), Expect = 6e-65
Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 21/312 (6%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VV 119
GQ+ L G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V
Sbjct: 11 GQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAV 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD 170
RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD
Sbjct: 71 PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNAD 130
Query: 171 YS--HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ + + ETW+ LE G+V+ +GLSNFN +Q++ +L +++P +Q+E H
Sbjct: 131 GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPY 190
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL 288
Q E++ CQ+ G+ V YSP GS E +++PV+ ++A+KYG++ QI+L
Sbjct: 191 LAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILL 250
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW------ 342
RWQ++RKV+ IPK++ P R+ +NI +FDFT +P+E++++N + + RY +P
Sbjct: 251 RWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRV 310
Query: 343 ---QNHPYYPFD 351
HP YPF+
Sbjct: 311 PRDAGHPLYPFN 322
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 248 bits (606), Expect = 6e-65
Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 21/312 (6%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VV 119
GQ+ L G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V
Sbjct: 11 GQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAV 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD 170
RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD
Sbjct: 71 PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNAD 130
Query: 171 YS--HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ + + ETW+ LE G+V+ +GLSNFN +Q++ +L +++P +Q+E H
Sbjct: 131 GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPY 190
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL 288
Q E++ CQ+ G+ V YSP GS E +++PV+ ++A+KYG++ QI+L
Sbjct: 191 LAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILL 250
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW------ 342
RWQ++RKV+ IPK++ P R+ +NI +FDFT +P+E++++N + + RY +P
Sbjct: 251 RWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRV 310
Query: 343 ---QNHPYYPFD 351
HP YPF+
Sbjct: 311 PRDAGHPLYPFN 322
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 248 bits (606), Expect = 6e-65
Identities = 122/312 (39%), Positives = 188/312 (60%), Gaps = 21/312 (6%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VV 119
GQ+ L G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V
Sbjct: 11 GQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAV 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD 170
RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD
Sbjct: 71 PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNAD 130
Query: 171 YS--HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEVHLQ 228
+ + + ETW+ LE G+V+ +GLSNFN +Q++ +L +++P +Q+E H
Sbjct: 131 GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPY 190
Query: 229 NVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVL 288
Q E++ CQ+ G+ V YSP GS E +++PV+ ++A+KYG++ QI+L
Sbjct: 191 LAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILL 250
Query: 289 RWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW------ 342
RWQ++RKV+ IPK++ P R+ +NI +FDFT +P+E++++N + + RY +P
Sbjct: 251 RWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRV 310
Query: 343 ---QNHPYYPFD 351
HP YPF+
Sbjct: 311 PRDAGHPLYPFN 322
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 228 bits (557), Expect = 5e-59
Identities = 120/295 (40%), Positives = 178/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWPIG + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 226 bits (552), Expect = 2e-58
Identities = 119/295 (40%), Positives = 177/295 (60%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>DQ223959-1|ABB03906.1| 404|Homo sapiens F-box and leucine-rich
repeat protein 20 variant b protein.
Length = 404
Score = 225 bits (550), Expect = 3e-58
Identities = 113/209 (54%), Positives = 141/209 (67%), Gaps = 20/209 (9%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
F+N DE IN+KLPKELLLRI S+LDVV+LCRCAQVS+ WN+LALDGSNWQRIDLF+FQR
Sbjct: 16 FSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQR 75
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITD-QT 485
D+EG V+ENIS+RCGGFLR+LSLRGC +GD +++T AQ+C NIE LNLN C K TD +
Sbjct: 76 DIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDAEG 135
Query: 486 C-------------------QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVN 526
C QAL R C L+ + L C + D +LK + CP L +N
Sbjct: 136 CPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLN 195
Query: 527 VSWCQSITESGVEALARGCPKLKSFICKG 555
+ C IT+ G+ + RGC KL+S G
Sbjct: 196 LQTCLQITDEGLITICRGCHKLQSLCASG 224
Score = 88.6 bits (210), Expect = 5e-17
Identities = 42/117 (35%), Positives = 65/117 (55%), Gaps = 1/117 (0%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
I+ + + CGG L+ L L+GC + D ++K + CP + LNL C +ITD+ + R
Sbjct: 155 IQALVRGCGG-LKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRG 213
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C KLQ + C +++D L AL CP L + V+ C +T+ G LAR C +L+
Sbjct: 214 CHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELE 270
Score = 78.6 bits (185), Expect = 6e-14
Identities = 34/101 (33%), Positives = 58/101 (57%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+ L GC +I D + L Q+CP + L + +C ++TD L R C +L+K++L+
Sbjct: 217 LQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEE 276
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARG 544
C ++D +L L+ CP L +++S C+ IT+ G+ L G
Sbjct: 277 CVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNG 317
Score = 70.9 bits (166), Expect = 1e-11
Identities = 30/106 (28%), Positives = 58/106 (54%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L QL++ C+ + ++ L + C ++ L L C ++ D+ + +G C +L +NL +
Sbjct: 139 LEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQT 198
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C ++D L + GC L + S C +IT++ + AL + CP+L+
Sbjct: 199 CLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLR 244
Score = 69.7 bits (163), Expect = 3e-11
Identities = 49/162 (30%), Positives = 82/162 (50%), Gaps = 11/162 (6%)
Query: 395 SLCR--CAQVSKLWNILALDGSNWQRIDLFEFQR--DVEGPVIENISQRCGGFLRQLSLR 450
SLC C+ ++ IL G N R+ + E R + +++ C L ++ L
Sbjct: 219 SLCASGCSNITDA--ILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHE-LEKMDLE 275
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGR-RCS--KLQKINLDSCPSV 507
C I D ++ L+ CP ++ L+L+ C+ ITD + LG C+ +L+ I LD+CP +
Sbjct: 276 ECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLI 335
Query: 508 SDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+D SL+ L C L + + CQ IT +G++ L P +K
Sbjct: 336 TDASLEHL-KSCHSLERIELYDCQQITRAGIKRLRTHLPNIK 376
Score = 68.5 bits (160), Expect = 6e-11
Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 1/159 (0%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLR 450
L+ +++ C QV+K + G + + +E ++ I C + L+L+
Sbjct: 139 LEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVT-LNLQ 197
Query: 451 GCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDI 510
C I D + T+ + C ++ L + C ITD ALG+ C +L+ + + C ++D+
Sbjct: 198 TCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDV 257
Query: 511 SLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
LA C L +++ C IT+S + L+ CP+L+
Sbjct: 258 GFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQ 296
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 220 bits (538), Expect = 1e-56
Identities = 118/295 (40%), Positives = 176/295 (59%), Gaps = 15/295 (5%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 19 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 78
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++T +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 139 LDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERK 295
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+++R+ ++R
Sbjct: 199 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 296 VVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+V IPK+V P+R+ EN +FDF L+ ++ + ++ + R +H YPF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 215 bits (526), Expect = 3e-55
Identities = 109/284 (38%), Positives = 176/284 (61%), Gaps = 14/284 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW+T HR V
Sbjct: 38 EVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELV 97
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQ 189
A+ +SLKK LDY+DLYL+H P+ L + S +D VD TW +E +
Sbjct: 98 RPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 157
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+ +V++
Sbjct: 158 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVA 217
Query: 248 YSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N +
Sbjct: 218 YSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQ 277
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 278 RIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 321
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 215 bits (526), Expect = 3e-55
Identities = 109/284 (38%), Positives = 176/284 (61%), Gaps = 14/284 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW+T HR V
Sbjct: 36 EVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQ 189
A+ +SLKK LDY+DLYL+H P+ L + S +D VD TW +E +
Sbjct: 96 RPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N +
Sbjct: 216 YSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQ 275
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 276 RIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 319
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 215 bits (526), Expect = 3e-55
Identities = 109/284 (38%), Positives = 176/284 (61%), Gaps = 14/284 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW+T HR V
Sbjct: 36 EVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQ 189
A+ +SLKK LDY+DLYL+H P+ L + S +D VD TW +E +
Sbjct: 96 RPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N +
Sbjct: 216 YSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQ 275
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 276 RIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 319
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 215 bits (526), Expect = 3e-55
Identities = 109/284 (38%), Positives = 176/284 (61%), Gaps = 14/284 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW+T HR V
Sbjct: 36 EVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQ 189
A+ +SLKK LDY+DLYL+H P+ L + S +D VD TW +E +
Sbjct: 96 RPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N +
Sbjct: 216 YSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQ 275
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 276 RIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 319
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 215 bits (526), Expect = 3e-55
Identities = 109/284 (38%), Positives = 176/284 (61%), Gaps = 14/284 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW+T HR V
Sbjct: 36 EVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQ 189
A+ +SLKK LDY+DLYL+H P+ L + S +D VD TW +E +
Sbjct: 96 RPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N +
Sbjct: 216 YSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQ 275
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 276 RIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 319
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 215 bits (526), Expect = 3e-55
Identities = 109/284 (38%), Positives = 176/284 (61%), Gaps = 14/284 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW+T HR V
Sbjct: 36 EVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQ 189
A+ +SLKK LDY+DLYL+H P+ L + S +D VD TW +E +
Sbjct: 96 RPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N +
Sbjct: 216 YSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQ 275
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 276 RIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 319
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 215 bits (526), Expect = 3e-55
Identities = 109/284 (38%), Positives = 176/284 (61%), Gaps = 14/284 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW+T HR V
Sbjct: 36 EVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQ 189
A+ +SLKK LDY+DLYL+H P+ L + S +D VD TW +E +
Sbjct: 96 RPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N +
Sbjct: 216 YSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQ 275
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 276 RIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 319
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 215 bits (525), Expect = 4e-55
Identities = 108/279 (38%), Positives = 165/279 (59%), Gaps = 14/279 (5%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
AID GYRH D A +Y+ E E+GEA++ K+ EG V+REDIF KLW T H V +
Sbjct: 44 AIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLE 103
Query: 146 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 194
+L+ L LDY+DLY++ P+ N + + + TW +E + G+V
Sbjct: 104 RTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLV 163
Query: 195 KGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
K +G+SNFN++QLE +L + + KP + Q+E H Q ++++FCQ +V+ YSP G
Sbjct: 164 KSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
Query: 253 SLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
+ V P + D +L+S+ ++Y KT QIVLR+ I+R VV IPK+ N +R++EN
Sbjct: 224 TSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKEN 283
Query: 312 INIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
IFDF+LT +E++ I + + R+ W++HP YPF
Sbjct: 284 FQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPF 322
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 215 bits (525), Expect = 4e-55
Identities = 108/279 (38%), Positives = 165/279 (59%), Gaps = 14/279 (5%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
AID GYRH D A +Y+ E E+GEA++ K+ EG V+REDIF KLW T H V +
Sbjct: 44 AIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLE 103
Query: 146 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 194
+L+ L LDY+DLY++ P+ N + + + TW +E + G+V
Sbjct: 104 RTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLV 163
Query: 195 KGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
K +G+SNFN++QLE +L + + KP + Q+E H Q ++++FCQ +V+ YSP G
Sbjct: 164 KSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
Query: 253 SLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
+ V P + D +L+S+ ++Y KT QIVLR+ I+R VV IPK+ N +R++EN
Sbjct: 224 TSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKEN 283
Query: 312 INIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
IFDF+LT +E++ I + + R+ W++HP YPF
Sbjct: 284 FQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPF 322
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 215 bits (525), Expect = 4e-55
Identities = 108/279 (38%), Positives = 165/279 (59%), Gaps = 14/279 (5%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
AID GYRH D A +Y+ E E+GEA++ K+ EG V+REDIF KLW T H V +
Sbjct: 44 AIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLE 103
Query: 146 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 194
+L+ L LDY+DLY++ P+ N + + + TW +E + G+V
Sbjct: 104 RTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLV 163
Query: 195 KGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
K +G+SNFN++QLE +L + + KP + Q+E H Q ++++FCQ +V+ YSP G
Sbjct: 164 KSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
Query: 253 SLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
+ V P + D +L+S+ ++Y KT QIVLR+ I+R VV IPK+ N +R++EN
Sbjct: 224 TSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKEN 283
Query: 312 INIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
IFDF+LT +E++ I + + R+ W++HP YPF
Sbjct: 284 FQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPF 322
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 215 bits (525), Expect = 4e-55
Identities = 108/279 (38%), Positives = 165/279 (59%), Gaps = 14/279 (5%)
Query: 86 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 145
AID GYRH D A +Y+ E E+GEA++ K+ EG V+REDIF KLW T H V +
Sbjct: 44 AIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLE 103
Query: 146 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 194
+L+ L LDY+DLY++ P+ N + + + TW +E + G+V
Sbjct: 104 RTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLV 163
Query: 195 KGIGLSNFNKQQLERVLKEGTI--KPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFG 252
K +G+SNFN++QLE +L + + KP + Q+E H Q ++++FCQ +V+ YSP G
Sbjct: 164 KSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
Query: 253 SLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEEN 311
+ V P + D +L+S+ ++Y KT QIVLR+ I+R VV IPK+ N +R++EN
Sbjct: 224 TSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKEN 283
Query: 312 INIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
IFDF+LT +E++ I + + R+ W++HP YPF
Sbjct: 284 FQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPF 322
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 215 bits (524), Expect = 5e-55
Identities = 122/312 (39%), Positives = 181/312 (58%), Gaps = 18/312 (5%)
Query: 54 ELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 113
ELS +A GL G KS ++++ V AID GYRH D A VY+ E E+GEA++ K
Sbjct: 6 ELSTKAKMPIVGL---GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 114 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DY 171
++E VKRED+FI +KLW T R V +A +LK L L Y+D+YL+HWP G + D
Sbjct: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122
Query: 172 SHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDA 220
D F++ W +E+ G+VK +G+SNF+ Q+E++L K G KP
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 221 IQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKY 279
Q+E H Q++++++C S+G+ V YSP GS R + E P ++DP + IA K+
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAKH 241
Query: 280 GKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
KT Q+++R+ I+R V+ IPK+V P R+ ENI +FDF L+ +E+ I F+ + R
Sbjct: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301
Query: 340 SFWQNHPYYPFD 351
+ YPFD
Sbjct: 302 LQSSHLEDYPFD 313
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 215 bits (524), Expect = 5e-55
Identities = 122/312 (39%), Positives = 181/312 (58%), Gaps = 18/312 (5%)
Query: 54 ELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 113
ELS +A GL G KS ++++ V AID GYRH D A VY+ E E+GEA++ K
Sbjct: 6 ELSTKAKMPIVGL---GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 114 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DY 171
++E VKRED+FI +KLW T R V +A +LK L L Y+D+YL+HWP G + D
Sbjct: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122
Query: 172 SHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDA 220
D F++ W +E+ G+VK +G+SNF+ Q+E++L K G KP
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 221 IQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKY 279
Q+E H Q++++++C S+G+ V YSP GS R + E P ++DP + IA K+
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAKH 241
Query: 280 GKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
KT Q+++R+ I+R V+ IPK+V P R+ ENI +FDF L+ +E+ I F+ + R
Sbjct: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301
Query: 340 SFWQNHPYYPFD 351
+ YPFD
Sbjct: 302 LQSSHLEDYPFD 313
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 215 bits (524), Expect = 5e-55
Identities = 122/312 (39%), Positives = 181/312 (58%), Gaps = 18/312 (5%)
Query: 54 ELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 113
ELS +A GL G KS ++++ V AID GYRH D A VY+ E E+GEA++ K
Sbjct: 6 ELSTKAKMPIVGL---GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 114 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DY 171
++E VKRED+FI +KLW T R V +A +LK L L Y+D+YL+HWP G + D
Sbjct: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122
Query: 172 SHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDA 220
D F++ W +E+ G+VK +G+SNF+ Q+E++L K G KP
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 221 IQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKY 279
Q+E H Q++++++C S+G+ V YSP GS R + E P ++DP + IA K+
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAKH 241
Query: 280 GKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
KT Q+++R+ I+R V+ IPK+V P R+ ENI +FDF L+ +E+ I F+ + R
Sbjct: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301
Query: 340 SFWQNHPYYPFD 351
+ YPFD
Sbjct: 302 LQSSHLEDYPFD 313
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 215 bits (524), Expect = 5e-55
Identities = 122/312 (39%), Positives = 181/312 (58%), Gaps = 18/312 (5%)
Query: 54 ELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 113
ELS +A GL G KS ++++ V AID GYRH D A VY+ E E+GEA++ K
Sbjct: 6 ELSTKAKMPIVGL---GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 114 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DY 171
++E VKRED+FI +KLW T R V +A +LK L L Y+D+YL+HWP G + D
Sbjct: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122
Query: 172 SHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDA 220
D F++ W +E+ G+VK +G+SNF+ Q+E++L K G KP
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 221 IQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKY 279
Q+E H Q++++++C S+G+ V YSP GS R + E P ++DP + IA K+
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAKH 241
Query: 280 GKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
KT Q+++R+ I+R V+ IPK+V P R+ ENI +FDF L+ +E+ I F+ + R
Sbjct: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301
Query: 340 SFWQNHPYYPFD 351
+ YPFD
Sbjct: 302 LQSSHLEDYPFD 313
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 215 bits (524), Expect = 5e-55
Identities = 108/284 (38%), Positives = 176/284 (61%), Gaps = 14/284 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW+T HR V
Sbjct: 36 EVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQ 189
A+ +SLKK LDY+DLYL+H P+ L + S +D VD TW +E +
Sbjct: 96 RPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV + ++ N +
Sbjct: 216 YSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLARSYNEQ 275
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 276 RIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 319
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 213 bits (520), Expect = 1e-54
Identities = 108/284 (38%), Positives = 176/284 (61%), Gaps = 14/284 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G V+REDIF T+KLW+T HR V
Sbjct: 36 EVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQ 189
A+ +SLKK LDY+DLYL+H P+ L + S +D VD TW +E +
Sbjct: 96 RPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N +
Sbjct: 216 YSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQ 275
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 276 RIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 319
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 213 bits (520), Expect = 1e-54
Identities = 118/296 (39%), Positives = 176/296 (59%), Gaps = 18/296 (6%)
Query: 54 ELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 113
ELS +A GL G KS ++++ V AID GYRH D A VY+ E E+GEA++ K
Sbjct: 6 ELSTKAKMPIVGL---GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 114 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DY 171
++E VKRED+FI +KLW T R V +A +LK L L Y+D+YL+HWP G + D
Sbjct: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122
Query: 172 SHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDA 220
D F++ W +E+ G+VK +G+SNF+ Q+E++L K G KP
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 221 IQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKY 279
Q+E H Q++++++C S+G+ V YSP GS R + E P ++DP + IA K+
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAKH 241
Query: 280 GKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTR 335
KT Q+++R+ I+R V+ IPK+V P R+ ENI +FDF L+ +E+ I F+ + R
Sbjct: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 108/284 (38%), Positives = 175/284 (61%), Gaps = 14/284 (4%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G V REDIF T+KLW+T HR V
Sbjct: 36 EVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWRGLEDAQ 189
A+ +SLKK LDY+DLYL+H P+ L + S +D VD TW +E +
Sbjct: 96 RPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPK 306
YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N +
Sbjct: 216 YSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQ 275
Query: 307 RLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 276 RIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 319
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 14 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 72
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 73 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 132
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 133 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 192
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 193 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 252
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 253 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 302
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 112/286 (39%), Positives = 176/286 (61%), Gaps = 18/286 (6%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW T + V
Sbjct: 36 EVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQ 189
A+ SLKKL LDY+DLYL+H+P+ L N VD TW +E +
Sbjct: 96 QPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN +QLE +L K G KP Q+E H Q ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVE--GP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
+S G+ RH V+ P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N
Sbjct: 216 HSALGT--QRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYN 273
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+R+ ENI +F+F LT ++++ ++G + + RY + F +HP YPF
Sbjct: 274 EQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPF 319
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 212 bits (518), Expect = 3e-54
Identities = 110/290 (37%), Positives = 172/290 (59%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 212 bits (517), Expect = 3e-54
Identities = 112/286 (39%), Positives = 176/286 (61%), Gaps = 18/286 (6%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW T + V
Sbjct: 36 EVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQ 189
A+ SLKKL LDY+DLYL+H+P+ L N VD TW +E +
Sbjct: 96 QPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN +QLE +L K G KP Q+E H Q ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVE--GP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
+S G+ RH V+ P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N
Sbjct: 216 HSALGT--QRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYN 273
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+R+ ENI +F+F LT ++++ ++G + + RY + F +HP YPF
Sbjct: 274 EQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPF 319
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 212 bits (517), Expect = 3e-54
Identities = 112/286 (39%), Positives = 176/286 (61%), Gaps = 18/286 (6%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW T + V
Sbjct: 21 EVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMV 80
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQ 189
A+ SLKKL LDY+DLYL+H+P+ L N VD TW +E +
Sbjct: 81 QPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCK 140
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN +QLE +L K G KP Q+E H Q ++++FC+S+ +V++
Sbjct: 141 DAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVA 200
Query: 248 YSPFGSLVARHGSTVE--GP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
+S G+ RH V+ P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N
Sbjct: 201 HSALGT--QRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYN 258
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+R+ ENI +F+F LT ++++ ++G + + RY + F +HP YPF
Sbjct: 259 EQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPF 304
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 212 bits (517), Expect = 3e-54
Identities = 112/286 (39%), Positives = 176/286 (61%), Gaps = 18/286 (6%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW T + V
Sbjct: 34 EVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMV 93
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQ 189
A+ SLKKL LDY+DLYL+H+P+ L N VD TW +E +
Sbjct: 94 QPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCK 153
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN +QLE +L K G KP Q+E H Q ++++FC+S+ +V++
Sbjct: 154 DAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVA 213
Query: 248 YSPFGSLVARHGSTVE--GP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
+S G+ RH V+ P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N
Sbjct: 214 HSALGT--QRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYN 271
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+R+ ENI +F+F LT ++++ ++G + + RY + F +HP YPF
Sbjct: 272 EQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPF 317
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 212 bits (517), Expect = 3e-54
Identities = 112/286 (39%), Positives = 176/286 (61%), Gaps = 18/286 (6%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW T + V
Sbjct: 36 EVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQ 189
A+ SLKKL LDY+DLYL+H+P+ L N VD TW +E +
Sbjct: 96 QPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN +QLE +L K G KP Q+E H Q ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVE--GP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
+S G+ RH V+ P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N
Sbjct: 216 HSALGT--QRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYN 273
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+R+ ENI +F+F LT ++++ ++G + + RY + F +HP YPF
Sbjct: 274 EQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPF 319
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 212 bits (517), Expect = 3e-54
Identities = 112/286 (39%), Positives = 176/286 (61%), Gaps = 18/286 (6%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW T + V
Sbjct: 36 EVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQ 189
A+ SLKKL LDY+DLYL+H+P+ L N VD TW +E +
Sbjct: 96 QPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN +QLE +L K G KP Q+E H Q ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVE--GP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
+S G+ RH V+ P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N
Sbjct: 216 HSALGT--QRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYN 273
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+R+ ENI +F+F LT ++++ ++G + + RY + F +HP YPF
Sbjct: 274 EQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPF 319
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 211 bits (516), Expect = 5e-54
Identities = 111/290 (38%), Positives = 175/290 (60%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G AV+ K+ +G VKREDIF T+KLW
Sbjct: 31 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAVRSKIADGSVKREDIFYTSKLWCNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL--NADYSHSD---------VDFMETWR 183
HR V A+ SLKK LDY+DLYL+H P+ L + S +D VD TW
Sbjct: 90 HRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN++QLE +L K G KP Q+E H + ++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS + P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT ++++ I+G D + Y + +HP YP+
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPY 319
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 211 bits (516), Expect = 5e-54
Identities = 112/286 (39%), Positives = 176/286 (61%), Gaps = 18/286 (6%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW T + V
Sbjct: 36 EVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQ 189
A+ SLKKL LDY+DLYL+H+P+ L N VD TW +E +
Sbjct: 96 QPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN +QLE +L K G KP Q+E H Q ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVE--GP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
+S G+ RH V+ P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N
Sbjct: 216 HSALGT--QRHKLWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYN 273
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+R+ ENI +F+F LT ++++ ++G + + RY + F +HP YPF
Sbjct: 274 EQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPF 319
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 211 bits (516), Expect = 5e-54
Identities = 112/286 (39%), Positives = 176/286 (61%), Gaps = 18/286 (6%)
Query: 81 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 140
+V AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW T + V
Sbjct: 36 EVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMV 95
Query: 141 AQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQ 189
A+ SLKKL LDY+DLYL+H+P+ L N VD TW +E +
Sbjct: 96 QPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCK 155
Query: 190 RMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMG 247
G+ K IG+SNFN +QLE +L K G KP Q+E H Q ++++FC+S+ +V++
Sbjct: 156 DAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVA 215
Query: 248 YSPFGSLVARHGSTVE--GP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVN 304
+S G+ RH V+ P ++DPVL ++A+K+ +T I LR+Q++R VV + K+ N
Sbjct: 216 HSALGT--QRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYN 273
Query: 305 PKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
+R+ ENI +F+F LT ++++ ++G + + RY + F +HP YPF
Sbjct: 274 EQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFVMDHPDYPF 319
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 211 bits (515), Expect = 6e-54
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 211 bits (515), Expect = 6e-54
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 211 bits (515), Expect = 6e-54
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 211 bits (515), Expect = 6e-54
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 211 bits (515), Expect = 6e-54
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 211 bits (515), Expect = 6e-54
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 211 bits (515), Expect = 6e-54
Identities = 121/312 (38%), Positives = 180/312 (57%), Gaps = 18/312 (5%)
Query: 54 ELSFEAPGQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 113
ELS +A GL G KS ++++ V AID GYRH D A VY+ E E+GEA++ K
Sbjct: 6 ELSTKAKMPIVGL---GTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 114 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--DY 171
++E VKRED+FI +KLW T R V +A +LK L Y+D+YL+HWP G + D
Sbjct: 63 IQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDL 122
Query: 172 SHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDA 220
D F++ W +E+ G+VK +G+SNF+ Q+E++L K G KP
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 221 IQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKY 279
Q+E H Q++++++C S+G+ V YSP GS R + E P ++DP + IA K+
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAKH 241
Query: 280 GKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLP 339
KT Q+++R+ I+R V+ IPK+V P R+ ENI +FDF L+ +E+ I F+ + R
Sbjct: 242 KKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAIILSFNRNWRACNV 301
Query: 340 SFWQNHPYYPFD 351
+ YPFD
Sbjct: 302 LQSSHLEDYPFD 313
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 211 bits (515), Expect = 6e-54
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 211 bits (515), Expect = 6e-54
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 211 bits (515), Expect = 6e-54
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 15/290 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YPF
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 210 bits (513), Expect = 1e-53
Identities = 108/289 (37%), Positives = 170/289 (58%), Gaps = 15/289 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L E +K P Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYP 349
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YP
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 210 bits (513), Expect = 1e-53
Identities = 109/289 (37%), Positives = 169/289 (58%), Gaps = 15/289 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ GY H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 31 KSKAL-EAVKLAIEAGYHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 89
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY DLYL+H+P+ + N VD TW
Sbjct: 90 HRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 149
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK--PDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L E +K P Q+E H Q+++++FC+S+
Sbjct: 150 AMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSK 209
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GS P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 210 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 269
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYP 349
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YP
Sbjct: 270 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 205 bits (501), Expect = 3e-52
Identities = 107/289 (37%), Positives = 169/289 (58%), Gaps = 15/289 (5%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + AI+ G+RH D+A +Y E+++G A++ K+ +G VKREDIF T+KLW
Sbjct: 28 KSKAL-EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNS 86
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 87 HRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 146
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + + K IG+SNFN+ LE +L K G +KP Q+E H Q+++++FC+S+
Sbjct: 147 AVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPVCNQVECHPYFNQRKLLDFCKSK 206
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIP 300
+V++ YS GSL P ++DPVL ++A+K+ +T I LR+Q++R VV +
Sbjct: 207 DIVLVAYSALGSLREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLA 266
Query: 301 KTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYP 349
K+ N +R+ +N+ +F+F LT +E++ I+G + + RY + P YP
Sbjct: 267 KSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 315
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 182 bits (444), Expect = 2e-45
Identities = 99/231 (42%), Positives = 139/231 (60%), Gaps = 15/231 (6%)
Query: 70 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 129
G KS Q+ + V AIDVGYRH D A VY+ E E+G A++ K+ E VVKRE++FI +K
Sbjct: 16 GTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK 75
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDF 178
LW T H + V A +L L LDY+DLYL+HWP G + + SD +
Sbjct: 76 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 135
Query: 179 METWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVE 236
++TW +E+ G+VK IG+SNFN Q+E +L K G KP QIE H Q+++++
Sbjct: 136 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 195
Query: 237 FCQSEGVVVMGYSPFGSLVARHGSTVEGPK-IDDPVLSSIAQKYGKTTPQI 286
+CQS+G+VV YSP GS R + E P ++DP + +IA K+ KTT Q+
Sbjct: 196 YCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 245
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 177 bits (432), Expect = 7e-44
Identities = 100/279 (35%), Positives = 167/279 (59%), Gaps = 18/279 (6%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+IF T KLW T R
Sbjct: 36 QAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRA 95
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGI 197
V A+ SLKKLG DY+DL+++H P + + + +DA I++ +
Sbjct: 96 ELVHPALERSLKKLGPDYVDLFIIHVPFAMK----QPGKELLP-----KDASGEIILETV 146
Query: 198 GLSNFNKQQLERVLKEGTI--KPDAIQI-EVHLQNVQKEMVEFCQSEGVVVMGYSPFGSL 254
L + +LE +L + + KP Q+ E H Q +++EFC+S+ +V++ YS GS
Sbjct: 147 ELCD--TWELELILNKPGLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQ 204
Query: 255 VARHGSTVEGPKI-DDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENIN 313
+ P + ++P+L SIA+K+ ++ Q+ LR+Q++R VV + K+ + +R++EN
Sbjct: 205 RDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQ 264
Query: 314 IFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFDK 352
IFDF LTP++++ I+G + + RY + NHPY+PF +
Sbjct: 265 IFDFELTPEDMKAIDGLNRNLRYDNAA---NHPYFPFSE 300
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 177 bits (432), Expect = 7e-44
Identities = 100/279 (35%), Positives = 167/279 (59%), Gaps = 18/279 (6%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+IF T KLW T R
Sbjct: 36 QAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRA 95
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGI 197
V A+ SLKKLG DY+DL+++H P + + + +DA I++ +
Sbjct: 96 ELVHPALERSLKKLGPDYVDLFIIHVPFAMK----QPGKELLP-----KDASGEIILETV 146
Query: 198 GLSNFNKQQLERVLKEGTI--KPDAIQI-EVHLQNVQKEMVEFCQSEGVVVMGYSPFGSL 254
L + +LE +L + + KP Q+ E H Q +++EFC+S+ +V++ YS GS
Sbjct: 147 ELCD--TWELELILNKPGLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQ 204
Query: 255 VARHGSTVEGPKI-DDPVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENIN 313
+ P + ++P+L SIA+K+ ++ Q+ LR+Q++R VV + K+ + +R++EN
Sbjct: 205 RDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQ 264
Query: 314 IFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPFDK 352
IFDF LTP++++ I+G + + RY + NHPY+PF +
Sbjct: 265 IFDFELTPEDMKAIDGLNRNLRYDNAA---NHPYFPFSE 300
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 160 bits (389), Expect = 1e-38
Identities = 86/222 (38%), Positives = 132/222 (59%), Gaps = 14/222 (6%)
Query: 105 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 164
E+G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 165 IGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-K 212
+ + N VD TW +E + G+ K IG+SNFN++QLE +L K
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 213 EG-TIKPDAIQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGP-KIDDP 270
G KP Q+E H Q+++++FC+S+ +V++ YS GS P ++DP
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDP 205
Query: 271 VLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENI 312
VL ++A+K+ +T I LR+Q++R VV + K+ N +R+ +N+
Sbjct: 206 VLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNV 247
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 155 bits (375), Expect = 6e-37
Identities = 85/218 (38%), Positives = 126/218 (57%), Gaps = 15/218 (6%)
Query: 75 KDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQ 134
K K L + V AI+ G+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+
Sbjct: 44 KSKAL-EAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNS 102
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWR 183
HR V A+ SLK L LDY+DLYL+H+P+ + N VD TW
Sbjct: 103 HRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWE 162
Query: 184 GLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQKEMVEFCQSE 241
+E + G+ K IG+SNFN + LE +L K G KP Q+E H Q+++++FC+S+
Sbjct: 163 AMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK 222
Query: 242 GVVVMGYSPFGSLVARHGSTVEGP-KIDDPVLSSIAQK 278
+V++ YS GS P ++DPVL ++A+K
Sbjct: 223 DIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 260
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 146 bits (353), Expect = 3e-34
Identities = 76/179 (42%), Positives = 108/179 (60%), Gaps = 8/179 (4%)
Query: 174 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEGT-IKPDAIQIEVHLQNVQ 231
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QIE H Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 232 KEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQ 291
K ++ FCQS V V Y P G GS ID+PV+ IA+++GK+ QI++R+Q
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG------GSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQ 257
Query: 292 IERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFWQNHPYYPF 350
I+R V+ IP ++ P ++ENI +FDF LT +++ I + + R + +NH YPF
Sbjct: 258 IQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHNDYPF 316
Score = 111 bits (266), Expect = 9e-24
Identities = 47/94 (50%), Positives = 66/94 (70%)
Query: 73 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 132
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 133 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 166
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 136 bits (330), Expect = 2e-31
Identities = 71/167 (42%), Positives = 102/167 (61%), Gaps = 8/167 (4%)
Query: 174 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEGT-IKPDAIQIEVHLQNVQ 231
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QIE H Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 232 KEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQ 291
K ++ FCQS V V Y P G GS ID+PV+ IA+++GK+ QI++R+Q
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG------GSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQ 257
Query: 292 IERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTL 338
I+R V+ IP ++ P ++ENI +FDF LT +++ I + + R +
Sbjct: 258 IQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAM 304
Score = 111 bits (266), Expect = 9e-24
Identities = 47/94 (50%), Positives = 66/94 (70%)
Query: 73 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 132
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 133 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 166
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 136 bits (330), Expect = 2e-31
Identities = 71/167 (42%), Positives = 102/167 (61%), Gaps = 8/167 (4%)
Query: 174 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEGT-IKPDAIQIEVHLQNVQ 231
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QIE H Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQ 203
Query: 232 KEMVEFCQSEGVVVMGYSPFGSLVARHGSTVEGPKIDDPVLSSIAQKYGKTTPQIVLRWQ 291
K ++ FCQS V V Y P G GS ID+PV+ IA+++GK+ QI++R+Q
Sbjct: 204 KNLISFCQSRDVSVTAYRPLG------GSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQ 257
Query: 292 IERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTL 338
I+R V+ IP ++ P ++ENI +FDF LT +++ I + + R +
Sbjct: 258 IQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAM 304
Score = 111 bits (266), Expect = 9e-24
Identities = 47/94 (50%), Positives = 66/94 (70%)
Query: 73 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 132
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 133 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 166
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 111 bits (266), Expect = 9e-24
Identities = 47/94 (50%), Positives = 66/94 (70%)
Query: 73 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 132
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 133 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 166
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 59.7 bits (138), Expect = 3e-08
Identities = 25/68 (36%), Positives = 43/68 (63%)
Query: 283 TPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGFDTHTRYTLPSFW 342
T +I++R+QI+R V+ IP ++ P ++ENI +FDF LT +++ I + + R +
Sbjct: 151 TWEILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPIT 210
Query: 343 QNHPYYPF 350
+NH YPF
Sbjct: 211 KNHKDYPF 218
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 111 bits (266), Expect = 9e-24
Identities = 47/94 (50%), Positives = 66/94 (70%)
Query: 73 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 132
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 133 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 166
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 62.5 bits (145), Expect = 4e-09
Identities = 27/80 (33%), Positives = 48/80 (60%)
Query: 271 VLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGF 330
+L+ ++ T QI++R+QI+R V+ IP ++ P ++ENI +FDF LT +++ I
Sbjct: 180 LLNKPGLRFKPLTNQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSL 239
Query: 331 DTHTRYTLPSFWQNHPYYPF 350
+ + R + +NH YPF
Sbjct: 240 NRNLRLAMFPITKNHKDYPF 259
Score = 57.2 bits (132), Expect = 2e-07
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 3/64 (4%)
Query: 174 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQ 231
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QI + Q +Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQ-IQ 202
Query: 232 KEMV 235
+ ++
Sbjct: 203 RNVI 206
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 111 bits (266), Expect = 9e-24
Identities = 47/94 (50%), Positives = 66/94 (70%)
Query: 73 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 132
K+ ++ + V AID GYRHFD A Y E+E+G ++ K++EG V+RED+FI TKLW
Sbjct: 13 KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWC 72
Query: 133 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 166
T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 73 TCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 57.2 bits (132), Expect = 2e-07
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 3/64 (4%)
Query: 174 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVHLQNVQ 231
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QI + Q +Q
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQ-IQ 202
Query: 232 KEMV 235
+ ++
Sbjct: 203 RNVI 206
Score = 52.8 bits (121), Expect = 3e-06
Identities = 22/68 (32%), Positives = 42/68 (61%)
Query: 271 VLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKINGF 330
+L+ ++ T QI++R+QI+R V+ IP ++ P ++ENI +FDF LT +++ I
Sbjct: 180 LLNKPGLRFKPLTNQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSL 239
Query: 331 DTHTRYTL 338
+ + R +
Sbjct: 240 NRNLRLAM 247
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 108 bits (259), Expect = 6e-23
Identities = 58/137 (42%), Positives = 79/137 (57%), Gaps = 12/137 (8%)
Query: 61 GQQCGLFQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG-VV 119
GQ+ L G KS+ Q++ V A+ VGYRH D A++Y E EIGEA+K V G V
Sbjct: 11 GQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAV 70
Query: 120 KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------NAD 170
RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYLMHWP NAD
Sbjct: 71 PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNAD 130
Query: 171 --YSHSDVDFMETWRGL 185
+ + ETW+ L
Sbjct: 131 GTICYDSTHYKETWKAL 147
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 96.3 bits (229), Expect = 3e-19
Identities = 43/90 (47%), Positives = 61/90 (67%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+IF T KLW T R
Sbjct: 36 QAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRA 95
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGL 167
V A+ SLKKLG DY+DL+++H P +
Sbjct: 96 ELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 96.3 bits (229), Expect = 3e-19
Identities = 43/90 (47%), Positives = 61/90 (67%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+IF T KLW T R
Sbjct: 36 QAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRA 95
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGL 167
V A+ SLKKLG DY+DL+++H P +
Sbjct: 96 ELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 96.3 bits (229), Expect = 3e-19
Identities = 43/90 (47%), Positives = 61/90 (67%)
Query: 78 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 137
Q + AIDVG+RH D+A +Y+ E+E+G+A+ K+ +G VKRE+IF T KLW T R
Sbjct: 36 QAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRA 95
Query: 138 TEVAQAINDSLKKLGLDYIDLYLMHWPIGL 167
V A+ SLKKLG DY+DL+++H P +
Sbjct: 96 ELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 95.9 bits (228), Expect = 4e-19
Identities = 44/89 (49%), Positives = 60/89 (67%)
Query: 79 LRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRT 138
+ + V AIDVGYRH D+A + E+ IG+A++ K+ G VKR+DIF TTK+W T R
Sbjct: 35 VEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPE 94
Query: 139 EVAQAINDSLKKLGLDYIDLYLMHWPIGL 167
V + + SLKKL L Y+DLYL H+P+ L
Sbjct: 95 LVQRGLEMSLKKLQLSYMDLYLFHFPVPL 123
>AL049953-1|CAB43222.1| 250|Homo sapiens hypothetical protein
protein.
Length = 250
Score = 83.0 bits (196), Expect = 3e-15
Identities = 41/116 (35%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Query: 434 ENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRC 493
E + + C G L+ L LRGC + D ++K + C + LNL C +ITD+ + R C
Sbjct: 2 EALVRGCRG-LKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGC 60
Query: 494 SKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+LQ + L C +++D SL AL CP L + + C +T++G LAR C +L+
Sbjct: 61 HRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELE 116
Score = 74.1 bits (174), Expect = 1e-12
Identities = 35/107 (32%), Positives = 60/107 (56%), Gaps = 2/107 (1%)
Query: 434 ENISQRCGGF--LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E + Q C G L+ L L GC ++ D S+ L +CP ++ L +C +TD L R
Sbjct: 51 EGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLAR 110
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGV 538
C +L+K++L+ C ++D +L L+ CP L +++ C+ IT+ G+
Sbjct: 111 NCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLPHCELITDDGI 157
Score = 66.1 bits (154), Expect = 3e-10
Identities = 35/123 (28%), Positives = 62/123 (50%), Gaps = 1/123 (0%)
Query: 428 VEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQ 487
+E +++I C + L+L+ C I D + + + C ++ L L+ C +TD +
Sbjct: 22 LEDEALKHIQNYCHELV-SLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLT 80
Query: 488 ALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPK 547
ALG C +LQ + C ++D LA C L +++ C IT+S + L+ CPK
Sbjct: 81 ALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPK 140
Query: 548 LKS 550
L++
Sbjct: 141 LQA 143
Score = 59.3 bits (137), Expect = 4e-08
Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+ L C + D LA++C +E ++L +C ITD T L C KLQ ++L
Sbjct: 89 LQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLPH 148
Query: 504 CPSVSDISLKALAD---GCPLLTHVNVSWCQSITESGVEAL--ARGCPKLKSFICKGKPR 558
C ++D + L++ G L + + C IT+ +E L RG +L+ + C+ R
Sbjct: 149 CELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTR 208
Query: 559 ESVPRLR 565
+ R+R
Sbjct: 209 AGIKRMR 215
Score = 55.2 bits (127), Expect = 6e-07
Identities = 42/164 (25%), Positives = 81/164 (49%), Gaps = 9/164 (5%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR--DVEGPVIENISQRCGGFLRQLS 448
L + L C+ ++ ++ AL G N R+ + E R + +++ C L ++
Sbjct: 63 LQALCLSGCSNLTDA-SLTAL-GLNCPRLQILEAARCSHLTDAGFTLLARNCHE-LEKMD 119
Query: 449 LRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR-CS--KLQKINLDSCP 505
L C I D ++ L+ CP ++ L+L C+ ITD L C +L+ + LD+C
Sbjct: 120 LEECILITDSTLIQLSIHCPKLQALSLPHCELITDDGILHLSNSTCGHERLRVLELDNCL 179
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
++D++L+ L + C L + + CQ +T +G++ + P +K
Sbjct: 180 LITDVALEHL-ENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 222
Score = 48.4 bits (110), Expect = 7e-05
Identities = 23/69 (33%), Positives = 37/69 (53%)
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
+AL R C L+ + L C + D +LK + + C L +N+ C IT+ GV + RGC
Sbjct: 2 EALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCH 61
Query: 547 KLKSFICKG 555
+L++ G
Sbjct: 62 RLQALCLSG 70
>BC075061-1|AAH75061.1| 491|Homo sapiens F-box and leucine-rich
repeat protein 7 protein.
Length = 491
Score = 76.2 bits (179), Expect = 3e-13
Identities = 36/107 (33%), Positives = 61/107 (57%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
LR LS+ C + D ++ +A+ C + LN C+ ITD + L + C+KL+ +++
Sbjct: 352 LRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGK 411
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
CP VSD L+ LA C L +++ C+SIT G++ +A C L++
Sbjct: 412 CPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQT 458
Score = 74.5 bits (175), Expect = 9e-13
Identities = 37/123 (30%), Positives = 70/123 (56%), Gaps = 1/123 (0%)
Query: 428 VEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQ 487
+E + I+ C L L LR C + D ++ L C +I++L+++ C+ ++D +
Sbjct: 285 LEDEGLHTIAAHCTQ-LTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLR 343
Query: 488 ALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPK 547
+ + S+L+ +++ C V+D+ ++ +A C L ++N C+ IT+ GVE LA+ C K
Sbjct: 344 EIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTK 403
Query: 548 LKS 550
LKS
Sbjct: 404 LKS 406
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/206 (24%), Positives = 99/206 (48%), Gaps = 15/206 (7%)
Query: 357 IADPFIKITRFTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNW 416
+ P I++ +++ I+R LP +++I S+L LCRCA+V + W LA D W
Sbjct: 96 LTHPLIRLASRPQKEQASIDR-LPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLW 154
Query: 417 QRIDLFEFQRDVEGPVIENISQRCGG------FLRQLSLRGCESIGDGSMKTLAQSCPNI 470
+ I L +V+ + + C L +++ GC + D + T+AQ CP +
Sbjct: 155 RTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPEL 214
Query: 471 EDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISL--KALADGCPL------L 522
L ++ C I+++ + C L+ +++ C V+ ISL +A PL +
Sbjct: 215 RRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISI 274
Query: 523 THVNVSWCQSITESGVEALARGCPKL 548
+++++ C + + G+ +A C +L
Sbjct: 275 RYLDMTDCFVLEDEGLHTIAAHCTQL 300
Score = 68.1 bits (159), Expect = 8e-11
Identities = 34/115 (29%), Positives = 64/115 (55%), Gaps = 2/115 (1%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
I +++ C LR L+ RGCE I D ++ LA++C ++ L++ KC ++D + L
Sbjct: 368 IRYVAKYCSK-LRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALN 426
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPK 547
C L++++L SC S++ L+ +A C L +NV C+ ++ + + R C +
Sbjct: 427 CFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCE-VSVEALRFVKRHCKR 480
Score = 66.1 bits (154), Expect = 3e-10
Identities = 29/111 (26%), Positives = 60/111 (54%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+++LS+ C + D ++ +A+ + L++ C ++TD + + + CSKL+ +N
Sbjct: 326 IKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARG 385
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICK 554
C ++D ++ LA C L +++ C ++++G+E LA C LK K
Sbjct: 386 CEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLK 436
Score = 65.3 bits (152), Expect = 6e-10
Identities = 29/112 (25%), Positives = 61/112 (54%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+R L + C + D + T+A C + L L +C ++TD+ + L C+ ++++++
Sbjct: 274 IRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSD 333
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKG 555
C VSD L+ +A L +++++ C +T+ G+ +A+ C KL+ +G
Sbjct: 334 CRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARG 385
Score = 46.4 bits (105), Expect = 3e-04
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 471 EDLNLNKCKKI-TDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSW 529
E +N+++ K+ T + CQ C L+ + + C ++D L +A CP L + VS
Sbjct: 162 ETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSG 221
Query: 530 CQSITESGVEALARGCPKLKSFICKG 555
C +I+ V + CP L+ G
Sbjct: 222 CYNISNEAVFDVVSLCPNLEHLDVSG 247
>AF199356-1|AAF09248.1| 491|Homo sapiens F-box protein FBL6
protein.
Length = 491
Score = 76.2 bits (179), Expect = 3e-13
Identities = 36/107 (33%), Positives = 61/107 (57%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
LR LS+ C + D ++ +A+ C + LN C+ ITD + L + C+KL+ +++
Sbjct: 352 LRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGK 411
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
CP VSD L+ LA C L +++ C+SIT G++ +A C L++
Sbjct: 412 CPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQT 458
Score = 74.5 bits (175), Expect = 9e-13
Identities = 37/123 (30%), Positives = 70/123 (56%), Gaps = 1/123 (0%)
Query: 428 VEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQ 487
+E + I+ C L L LR C + D ++ L C +I++L+++ C+ ++D +
Sbjct: 285 LEDEGLHTIAAHCTQ-LTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLR 343
Query: 488 ALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPK 547
+ + S+L+ +++ C V+D+ ++ +A C L ++N C+ IT+ GVE LA+ C K
Sbjct: 344 EIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTK 403
Query: 548 LKS 550
LKS
Sbjct: 404 LKS 406
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/206 (24%), Positives = 99/206 (48%), Gaps = 15/206 (7%)
Query: 357 IADPFIKITRFTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNW 416
+ P I++ +++ I+R LP +++I S+L LCRCA+V + W LA D W
Sbjct: 96 LTHPLIRLASRPQKEQASIDR-LPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLW 154
Query: 417 QRIDLFEFQRDVEGPVIENISQRCGG------FLRQLSLRGCESIGDGSMKTLAQSCPNI 470
+ I L +V+ + + C L +++ GC + D + T+AQ CP +
Sbjct: 155 RTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPEL 214
Query: 471 EDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISL--KALADGCPL------L 522
L ++ C I+++ + C L+ +++ C V+ ISL +A PL +
Sbjct: 215 RRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISI 274
Query: 523 THVNVSWCQSITESGVEALARGCPKL 548
+++++ C + + G+ +A C +L
Sbjct: 275 RYLDMTDCFVLEDEGLHTIAAHCTQL 300
Score = 68.1 bits (159), Expect = 8e-11
Identities = 34/115 (29%), Positives = 64/115 (55%), Gaps = 2/115 (1%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
I +++ C LR L+ RGCE I D ++ LA++C ++ L++ KC ++D + L
Sbjct: 368 IRYVAKYCSK-LRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALN 426
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPK 547
C L++++L SC S++ L+ +A C L +NV C+ ++ + + R C +
Sbjct: 427 CFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCE-VSVEALRFVKRHCKR 480
Score = 66.1 bits (154), Expect = 3e-10
Identities = 29/111 (26%), Positives = 60/111 (54%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+++LS+ C + D ++ +A+ + L++ C ++TD + + + CSKL+ +N
Sbjct: 326 IKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARG 385
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICK 554
C ++D ++ LA C L +++ C ++++G+E LA C LK K
Sbjct: 386 CEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLK 436
Score = 65.3 bits (152), Expect = 6e-10
Identities = 29/112 (25%), Positives = 61/112 (54%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+R L + C + D + T+A C + L L +C ++TD+ + L C+ ++++++
Sbjct: 274 IRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSD 333
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKG 555
C VSD L+ +A L +++++ C +T+ G+ +A+ C KL+ +G
Sbjct: 334 CRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARG 385
Score = 46.4 bits (105), Expect = 3e-04
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 471 EDLNLNKCKKI-TDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSW 529
E +N+++ K+ T + CQ C L+ + + C ++D L +A CP L + VS
Sbjct: 162 ETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSG 221
Query: 530 CQSITESGVEALARGCPKLKSFICKG 555
C +I+ V + CP L+ G
Sbjct: 222 CYNISNEAVFDVVSLCPNLEHLDVSG 247
>AF174593-1|AAF04514.1| 483|Homo sapiens F-box protein Fbl7
protein.
Length = 483
Score = 76.2 bits (179), Expect = 3e-13
Identities = 36/107 (33%), Positives = 61/107 (57%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
LR LS+ C + D ++ +A+ C + LN C+ ITD + L + C+KL+ +++
Sbjct: 344 LRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGK 403
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
CP VSD L+ LA C L +++ C+SIT G++ +A C L++
Sbjct: 404 CPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQT 450
Score = 74.5 bits (175), Expect = 9e-13
Identities = 37/123 (30%), Positives = 70/123 (56%), Gaps = 1/123 (0%)
Query: 428 VEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQ 487
+E + I+ C L L LR C + D ++ L C +I++L+++ C+ ++D +
Sbjct: 277 LEDEGLHTIAAHCTQ-LTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLR 335
Query: 488 ALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPK 547
+ + S+L+ +++ C V+D+ ++ +A C L ++N C+ IT+ GVE LA+ C K
Sbjct: 336 EIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTK 395
Query: 548 LKS 550
LKS
Sbjct: 396 LKS 398
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/206 (24%), Positives = 99/206 (48%), Gaps = 15/206 (7%)
Query: 357 IADPFIKITRFTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNW 416
+ P I++ +++ I+R LP +++I S+L LCRCA+V + W LA D W
Sbjct: 88 LTHPLIRLASRPQKEQASIDR-LPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLW 146
Query: 417 QRIDLFEFQRDVEGPVIENISQRCGG------FLRQLSLRGCESIGDGSMKTLAQSCPNI 470
+ I L +V+ + + C L +++ GC + D + T+AQ CP +
Sbjct: 147 RTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPEL 206
Query: 471 EDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISL--KALADGCPL------L 522
L ++ C I+++ + C L+ +++ C V+ ISL +A PL +
Sbjct: 207 RRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISI 266
Query: 523 THVNVSWCQSITESGVEALARGCPKL 548
+++++ C + + G+ +A C +L
Sbjct: 267 RYLDMTDCFVLEDEGLHTIAAHCTQL 292
Score = 68.1 bits (159), Expect = 8e-11
Identities = 34/115 (29%), Positives = 64/115 (55%), Gaps = 2/115 (1%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
I +++ C LR L+ RGCE I D ++ LA++C ++ L++ KC ++D + L
Sbjct: 360 IRYVAKYCSK-LRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALN 418
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPK 547
C L++++L SC S++ L+ +A C L +NV C+ ++ + + R C +
Sbjct: 419 CFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCE-VSVEALRFVKRHCKR 472
Score = 66.1 bits (154), Expect = 3e-10
Identities = 29/111 (26%), Positives = 60/111 (54%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+++LS+ C + D ++ +A+ + L++ C ++TD + + + CSKL+ +N
Sbjct: 318 IKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARG 377
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICK 554
C ++D ++ LA C L +++ C ++++G+E LA C LK K
Sbjct: 378 CEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLK 428
Score = 65.3 bits (152), Expect = 6e-10
Identities = 29/112 (25%), Positives = 61/112 (54%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+R L + C + D + T+A C + L L +C ++TD+ + L C+ ++++++
Sbjct: 266 IRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSD 325
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKG 555
C VSD L+ +A L +++++ C +T+ G+ +A+ C KL+ +G
Sbjct: 326 CRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARG 377
Score = 46.4 bits (105), Expect = 3e-04
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 471 EDLNLNKCKKI-TDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSW 529
E +N+++ K+ T + CQ C L+ + + C ++D L +A CP L + VS
Sbjct: 154 ETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSG 213
Query: 530 CQSITESGVEALARGCPKLKSFICKG 555
C +I+ V + CP L+ G
Sbjct: 214 CYNISNEAVFDVVSLCPNLEHLDVSG 239
>AB020647-1|BAA74863.2| 523|Homo sapiens KIAA0840 protein protein.
Length = 523
Score = 76.2 bits (179), Expect = 3e-13
Identities = 36/107 (33%), Positives = 61/107 (57%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
LR LS+ C + D ++ +A+ C + LN C+ ITD + L + C+KL+ +++
Sbjct: 384 LRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGK 443
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
CP VSD L+ LA C L +++ C+SIT G++ +A C L++
Sbjct: 444 CPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQT 490
Score = 74.5 bits (175), Expect = 9e-13
Identities = 37/123 (30%), Positives = 70/123 (56%), Gaps = 1/123 (0%)
Query: 428 VEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQ 487
+E + I+ C L L LR C + D ++ L C +I++L+++ C+ ++D +
Sbjct: 317 LEDEGLHTIAAHCTQ-LTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLR 375
Query: 488 ALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPK 547
+ + S+L+ +++ C V+D+ ++ +A C L ++N C+ IT+ GVE LA+ C K
Sbjct: 376 EIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTK 435
Query: 548 LKS 550
LKS
Sbjct: 436 LKS 438
Score = 74.1 bits (174), Expect = 1e-12
Identities = 51/206 (24%), Positives = 99/206 (48%), Gaps = 15/206 (7%)
Query: 357 IADPFIKITRFTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNW 416
+ P I++ +++ I+R LP +++I S+L LCRCA+V + W LA D W
Sbjct: 128 LTHPLIRLASRPQKEQASIDR-LPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLW 186
Query: 417 QRIDLFEFQRDVEGPVIENISQRCGG------FLRQLSLRGCESIGDGSMKTLAQSCPNI 470
+ I L +V+ + + C L +++ GC + D + T+AQ CP +
Sbjct: 187 RTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPEL 246
Query: 471 EDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISL--KALADGCPL------L 522
L ++ C I+++ + C L+ +++ C V+ ISL +A PL +
Sbjct: 247 RRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISI 306
Query: 523 THVNVSWCQSITESGVEALARGCPKL 548
+++++ C + + G+ +A C +L
Sbjct: 307 RYLDMTDCFVLEDEGLHTIAAHCTQL 332
Score = 68.1 bits (159), Expect = 8e-11
Identities = 34/115 (29%), Positives = 64/115 (55%), Gaps = 2/115 (1%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
I +++ C LR L+ RGCE I D ++ LA++C ++ L++ KC ++D + L
Sbjct: 400 IRYVAKYCSK-LRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALN 458
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPK 547
C L++++L SC S++ L+ +A C L +NV C+ ++ + + R C +
Sbjct: 459 CFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCE-VSVEALRFVKRHCKR 512
Score = 66.1 bits (154), Expect = 3e-10
Identities = 29/111 (26%), Positives = 60/111 (54%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+++LS+ C + D ++ +A+ + L++ C ++TD + + + CSKL+ +N
Sbjct: 358 IKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARG 417
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICK 554
C ++D ++ LA C L +++ C ++++G+E LA C LK K
Sbjct: 418 CEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLK 468
Score = 65.3 bits (152), Expect = 6e-10
Identities = 29/112 (25%), Positives = 61/112 (54%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+R L + C + D + T+A C + L L +C ++TD+ + L C+ ++++++
Sbjct: 306 IRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSD 365
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKG 555
C VSD L+ +A L +++++ C +T+ G+ +A+ C KL+ +G
Sbjct: 366 CRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARG 417
Score = 46.4 bits (105), Expect = 3e-04
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 471 EDLNLNKCKKI-TDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSW 529
E +N+++ K+ T + CQ C L+ + + C ++D L +A CP L + VS
Sbjct: 194 ETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSG 253
Query: 530 CQSITESGVEALARGCPKLKSFICKG 555
C +I+ V + CP L+ G
Sbjct: 254 CYNISNEAVFDVVSLCPNLEHLDVSG 279
>BC130566-1|AAI30567.1| 300|Homo sapiens FBXL15 protein protein.
Length = 300
Score = 73.3 bits (172), Expect = 2e-12
Identities = 41/126 (32%), Positives = 70/126 (55%), Gaps = 4/126 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALG-RRCSKLQKINLD 502
L++LSL C+ + +++ LA CP +E+L+L C+++ D+ L RR + L+ ++L
Sbjct: 142 LQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLA 201
Query: 503 SCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSF---ICKGKPRE 559
+V D +++ LA CP L H++++ C + GV LA CP L+S C
Sbjct: 202 VNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAES 261
Query: 560 SVPRLR 565
S+ RLR
Sbjct: 262 SLSRLR 267
Score = 62.1 bits (144), Expect = 5e-09
Identities = 38/163 (23%), Positives = 83/163 (50%), Gaps = 3/163 (1%)
Query: 383 LLLRILSYLDVVSLCRCAQVSKLW-NILALDGSNWQRIDLFEFQRDVEGPVIENISQRCG 441
LL +L+ + + L R +VS+ + +++ L + +R D + + + + +
Sbjct: 28 LLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAE 87
Query: 442 GFLRQLSLRGC-ESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKIN 500
G L++L+L C E + D + + P + + L C +++ + AL C +LQ+++
Sbjct: 88 G-LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLS 146
Query: 501 LDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR 543
L C V ++L+ LAD CP L ++++ C+ + + + LA+
Sbjct: 147 LAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQ 189
Score = 61.7 bits (143), Expect = 7e-09
Identities = 43/152 (28%), Positives = 69/152 (45%), Gaps = 4/152 (2%)
Query: 394 VSLCRCAQVSK-LWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGC 452
V+L C Q+S+ LA QR+ L V+G + ++ RC L +L L C
Sbjct: 119 VALGGCGQLSRRALGALAEGCPRLQRLSLAHCDW-VDGLALRGLADRCPA-LEELDLTAC 176
Query: 453 ESIGDGSMKTLAQSC-PNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDIS 511
+ D ++ LAQ + L+L + D Q L R C +L ++L C V
Sbjct: 177 RQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDG 236
Query: 512 LKALADGCPLLTHVNVSWCQSITESGVEALAR 543
++ LA+ CP+L + V C + ES + L +
Sbjct: 237 VRTLAEYCPVLRSLRVRHCHHVAESSLSRLRK 268
Score = 45.2 bits (102), Expect = 7e-04
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Query: 459 SMKTLAQSCPNIEDLNLNKCKK-ITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALAD 517
++ L + +++L L C + ++D+ + R +L+ + L C +S +L ALA+
Sbjct: 78 ALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAE 137
Query: 518 GCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
GCP L ++++ C + + LA CP L+
Sbjct: 138 GCPRLQRLSLAHCDWVDGLALRGLADRCPALE 169
Score = 39.9 bits (89), Expect = 0.025
Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
+V ++ +++ C L L L GC +G ++TLA+ CP + L + C + + +
Sbjct: 205 NVGDAAVQELARNCPE-LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSL 263
Query: 487 QALGRR 492
L +R
Sbjct: 264 SRLRKR 269
>BC036120-1|AAH36120.1| 296|Homo sapiens FBXL15 protein protein.
Length = 296
Score = 73.3 bits (172), Expect = 2e-12
Identities = 41/126 (32%), Positives = 70/126 (55%), Gaps = 4/126 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALG-RRCSKLQKINLD 502
L++LSL C+ + +++ LA CP +E+L+L C+++ D+ L RR + L+ ++L
Sbjct: 138 LQRLSLAHCDWVDGLALRGLADHCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLA 197
Query: 503 SCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSF---ICKGKPRE 559
+V D +++ LA CP L H++++ C + GV LA CP L+S C
Sbjct: 198 VNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAES 257
Query: 560 SVPRLR 565
S+ RLR
Sbjct: 258 SLSRLR 263
Score = 62.1 bits (144), Expect = 5e-09
Identities = 38/163 (23%), Positives = 83/163 (50%), Gaps = 3/163 (1%)
Query: 383 LLLRILSYLDVVSLCRCAQVSKLW-NILALDGSNWQRIDLFEFQRDVEGPVIENISQRCG 441
LL +L+ + + L R +VS+ + +++ L + +R D + + + + +
Sbjct: 24 LLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAE 83
Query: 442 GFLRQLSLRGC-ESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKIN 500
G L++L+L C E + D + + P + + L C +++ + AL C +LQ+++
Sbjct: 84 G-LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLS 142
Query: 501 LDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR 543
L C V ++L+ LAD CP L ++++ C+ + + + LA+
Sbjct: 143 LAHCDWVDGLALRGLADHCPALEELDLTACRQLKDEAIVYLAQ 185
Score = 59.7 bits (138), Expect = 3e-08
Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 4/152 (2%)
Query: 394 VSLCRCAQVSK-LWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGC 452
V+L C Q+S+ LA QR+ L V+G + ++ C L +L L C
Sbjct: 115 VALGGCGQLSRRALGALAEGCPRLQRLSLAHCDW-VDGLALRGLADHCPA-LEELDLTAC 172
Query: 453 ESIGDGSMKTLAQSC-PNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDIS 511
+ D ++ LAQ + L+L + D Q L R C +L ++L C V
Sbjct: 173 RQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDG 232
Query: 512 LKALADGCPLLTHVNVSWCQSITESGVEALAR 543
++ LA+ CP+L + V C + ES + L +
Sbjct: 233 VRTLAEYCPVLRSLRVRHCHHVAESSLSRLRK 264
Score = 45.2 bits (102), Expect = 7e-04
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Query: 459 SMKTLAQSCPNIEDLNLNKCKK-ITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALAD 517
++ L + +++L L C + ++D+ + R +L+ + L C +S +L ALA+
Sbjct: 74 ALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAE 133
Query: 518 GCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
GCP L ++++ C + + LA CP L+
Sbjct: 134 GCPRLQRLSLAHCDWVDGLALRGLADHCPALE 165
Score = 39.9 bits (89), Expect = 0.025
Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
+V ++ +++ C L L L GC +G ++TLA+ CP + L + C + + +
Sbjct: 201 NVGDAAVQELARNCPE-LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSL 259
Query: 487 QALGRR 492
L +R
Sbjct: 260 SRLRKR 265
>BC002912-1|AAH02912.1| 296|Homo sapiens FBXL15 protein protein.
Length = 296
Score = 73.3 bits (172), Expect = 2e-12
Identities = 41/126 (32%), Positives = 70/126 (55%), Gaps = 4/126 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALG-RRCSKLQKINLD 502
L++LSL C+ + +++ LA CP +E+L+L C+++ D+ L RR + L+ ++L
Sbjct: 138 LQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLA 197
Query: 503 SCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSF---ICKGKPRE 559
+V D +++ LA CP L H++++ C + GV LA CP L+S C
Sbjct: 198 VNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAES 257
Query: 560 SVPRLR 565
S+ RLR
Sbjct: 258 SLSRLR 263
Score = 62.1 bits (144), Expect = 5e-09
Identities = 38/163 (23%), Positives = 83/163 (50%), Gaps = 3/163 (1%)
Query: 383 LLLRILSYLDVVSLCRCAQVSKLW-NILALDGSNWQRIDLFEFQRDVEGPVIENISQRCG 441
LL +L+ + + L R +VS+ + +++ L + +R D + + + + +
Sbjct: 24 LLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAE 83
Query: 442 GFLRQLSLRGC-ESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKIN 500
G L++L+L C E + D + + P + + L C +++ + AL C +LQ+++
Sbjct: 84 G-LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLS 142
Query: 501 LDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR 543
L C V ++L+ LAD CP L ++++ C+ + + + LA+
Sbjct: 143 LAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQ 185
Score = 61.7 bits (143), Expect = 7e-09
Identities = 43/152 (28%), Positives = 69/152 (45%), Gaps = 4/152 (2%)
Query: 394 VSLCRCAQVSK-LWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGC 452
V+L C Q+S+ LA QR+ L V+G + ++ RC L +L L C
Sbjct: 115 VALGGCGQLSRRALGALAEGCPRLQRLSLAHCDW-VDGLALRGLADRCPA-LEELDLTAC 172
Query: 453 ESIGDGSMKTLAQSC-PNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDIS 511
+ D ++ LAQ + L+L + D Q L R C +L ++L C V
Sbjct: 173 RQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDG 232
Query: 512 LKALADGCPLLTHVNVSWCQSITESGVEALAR 543
++ LA+ CP+L + V C + ES + L +
Sbjct: 233 VRTLAEYCPVLRSLRVRHCHHVAESSLSRLRK 264
Score = 45.2 bits (102), Expect = 7e-04
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Query: 459 SMKTLAQSCPNIEDLNLNKCKK-ITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALAD 517
++ L + +++L L C + ++D+ + R +L+ + L C +S +L ALA+
Sbjct: 74 ALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAE 133
Query: 518 GCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
GCP L ++++ C + + LA CP L+
Sbjct: 134 GCPRLQRLSLAHCDWVDGLALRGLADRCPALE 165
Score = 39.9 bits (89), Expect = 0.025
Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
+V ++ +++ C L L L GC +G ++TLA+ CP + L + C + + +
Sbjct: 201 NVGDAAVQELARNCPE-LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSL 259
Query: 487 QALGRR 492
L +R
Sbjct: 260 SRLRKR 265
>AL121928-8|CAI12522.2| 296|Homo sapiens novel protein protein.
Length = 296
Score = 73.3 bits (172), Expect = 2e-12
Identities = 41/126 (32%), Positives = 70/126 (55%), Gaps = 4/126 (3%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALG-RRCSKLQKINLD 502
L++LSL C+ + +++ LA CP +E+L+L C+++ D+ L RR + L+ ++L
Sbjct: 138 LQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLA 197
Query: 503 SCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSF---ICKGKPRE 559
+V D +++ LA CP L H++++ C + GV LA CP L+S C
Sbjct: 198 VNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAES 257
Query: 560 SVPRLR 565
S+ RLR
Sbjct: 258 SLSRLR 263
Score = 62.1 bits (144), Expect = 5e-09
Identities = 38/163 (23%), Positives = 83/163 (50%), Gaps = 3/163 (1%)
Query: 383 LLLRILSYLDVVSLCRCAQVSKLW-NILALDGSNWQRIDLFEFQRDVEGPVIENISQRCG 441
LL +L+ + + L R +VS+ + +++ L + +R D + + + + +
Sbjct: 24 LLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAE 83
Query: 442 GFLRQLSLRGC-ESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKIN 500
G L++L+L C E + D + + P + + L C +++ + AL C +LQ+++
Sbjct: 84 G-LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLS 142
Query: 501 LDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR 543
L C V ++L+ LAD CP L ++++ C+ + + + LA+
Sbjct: 143 LAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQ 185
Score = 61.7 bits (143), Expect = 7e-09
Identities = 43/152 (28%), Positives = 69/152 (45%), Gaps = 4/152 (2%)
Query: 394 VSLCRCAQVSK-LWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGC 452
V+L C Q+S+ LA QR+ L V+G + ++ RC L +L L C
Sbjct: 115 VALGGCGQLSRRALGALAEGCPRLQRLSLAHCDW-VDGLALRGLADRCPA-LEELDLTAC 172
Query: 453 ESIGDGSMKTLAQSC-PNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDIS 511
+ D ++ LAQ + L+L + D Q L R C +L ++L C V
Sbjct: 173 RQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDG 232
Query: 512 LKALADGCPLLTHVNVSWCQSITESGVEALAR 543
++ LA+ CP+L + V C + ES + L +
Sbjct: 233 VRTLAEYCPVLRSLRVRHCHHVAESSLSRLRK 264
Score = 45.2 bits (102), Expect = 7e-04
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Query: 459 SMKTLAQSCPNIEDLNLNKCKK-ITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALAD 517
++ L + +++L L C + ++D+ + R +L+ + L C +S +L ALA+
Sbjct: 74 ALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAE 133
Query: 518 GCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
GCP L ++++ C + + LA CP L+
Sbjct: 134 GCPRLQRLSLAHCDWVDGLALRGLADRCPALE 165
Score = 39.9 bits (89), Expect = 0.025
Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
+V ++ +++ C L L L GC +G ++TLA+ CP + L + C + + +
Sbjct: 201 NVGDAAVQELARNCPE-LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSL 259
Query: 487 QALGRR 492
L +R
Sbjct: 260 SRLRKR 265
>BC028132-1|AAH28132.1| 418|Homo sapiens F-box and leucine-rich
repeat protein 14 protein.
Length = 418
Score = 72.5 bits (170), Expect = 4e-12
Identities = 56/180 (31%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 372 ENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGP 431
E HI+ P ELL I YLDV R AQV W A S W+ ++ R
Sbjct: 2 ETHISCLFP-ELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPS 60
Query: 432 VIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC-QALG 490
+ ++ R ++ LSLR S+ + Q NIE LNL+ C +TD A
Sbjct: 61 LFPSLQARGIRRVQILSLR-------RSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFV 113
Query: 491 RRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
+ L+ +NL C ++D SL +A L + + C +IT +G+ +A G +LKS
Sbjct: 114 QEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKS 173
Score = 62.1 bits (144), Expect = 5e-09
Identities = 37/114 (32%), Positives = 64/114 (56%), Gaps = 2/114 (1%)
Query: 437 SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKL 496
++ C G L QL+L+ C+ + D S+K +++ + LNL+ C I+D L S L
Sbjct: 198 AEGCLG-LEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGS-L 255
Query: 497 QKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
+ +NL SC ++SD + LA G L+ ++VS+C + + + +A+G LKS
Sbjct: 256 RSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKS 309
Score = 59.3 bits (137), Expect = 4e-08
Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 8/112 (7%)
Query: 444 LRQLSLRGCESIGD-------GSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKL 496
L+ L+LR C + D G ++ A+ C +E L L C+K+TD + + + R + L
Sbjct: 171 LKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGL 230
Query: 497 QKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
+ +NL C +SD L L+ L +N+ C +I+++G+ LA G +L
Sbjct: 231 RLLNLSFCGGISDAGLLHLSH-MGSLRSLNLRSCDNISDTGIMHLAMGSLRL 281
Score = 58.8 bits (136), Expect = 5e-08
Identities = 34/115 (29%), Positives = 59/115 (51%), Gaps = 7/115 (6%)
Query: 442 GFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINL 501
G LR L+L C+ I D S+ +AQ +E L L C IT+ + +L+ +NL
Sbjct: 117 GSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNL 176
Query: 502 DSCPSVSDISL-------KALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
SC +SD+ + ++ A+GC L + + CQ +T+ ++ ++RG L+
Sbjct: 177 RSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLR 231
Score = 56.4 bits (130), Expect = 3e-07
Identities = 31/107 (28%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Query: 442 GFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINL 501
G LR L+LR C++I D + LA + L+++ C K+ DQ+ + + L+ ++L
Sbjct: 253 GSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSL 312
Query: 502 DSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
SC +SD + + L +N+ C IT+ G+E +A +L
Sbjct: 313 CSC-HISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQL 358
Score = 42.3 bits (95), Expect = 0.005
Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 4/105 (3%)
Query: 436 ISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSK 495
I+Q G L+ LSL C I D + + + + LN+ +C +ITD+ + + S+
Sbjct: 300 IAQGLDG-LKSLSLCSCH-ISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQ 357
Query: 496 LQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEA 540
L I+L C ++ L+ + P L +N+ Q +T+S EA
Sbjct: 358 LTGIDLYGCTRITKRGLERITQ-LPCLKVLNLGLWQ-MTDSEKEA 400
>BC126146-1|AAI26147.1| 303|Homo sapiens F-box and leucine-rich
repeat protein 17 protein.
Length = 303
Score = 72.1 bits (169), Expect = 5e-12
Identities = 33/111 (29%), Positives = 62/111 (55%), Gaps = 1/111 (0%)
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
+C G LR + R C+ + D S+ +A CP ++ +++ K+TD+ + LG +C +L+
Sbjct: 12 KCPGLLRYTAYR-CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKD 70
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
I+ C +SD + +A GC L + + + +T+ V+A A CP+L+
Sbjct: 71 IHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQ 121
Score = 62.5 bits (145), Expect = 4e-09
Identities = 31/100 (31%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+++ + + + D +K L C ++D++ +C KI+D+ + + C KLQ+I +
Sbjct: 42 LQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQE 101
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR 543
V+D S+KA A+ CP L +V C S+T GV L +
Sbjct: 102 NKLVTDQSVKAFAEHCPELQYVGFMGC-SVTSKGVIHLTK 140
Score = 59.3 bits (137), Expect = 4e-08
Identities = 27/95 (28%), Positives = 50/95 (52%)
Query: 455 IGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISLKA 514
+ D + LA CP + +CK+++D + A+ C LQK+++ + ++D LK
Sbjct: 1 MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
Query: 515 LADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L C L ++ C I++ G+ +A+GC KL+
Sbjct: 61 LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQ 95
Score = 50.0 bits (114), Expect = 2e-05
Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L L LR + + ++ + + C N+ LNL I D+ + + + L+++ L S
Sbjct: 144 LSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVS 203
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C ++D +L A+ + V+V WC+ IT+ G +A+ L+
Sbjct: 204 C-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLR 248
Score = 47.6 bits (108), Expect = 1e-04
Identities = 30/122 (24%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
+++ + I +RC L L+L I D ++ +A+ N+++L L CK ITD
Sbjct: 154 ELDNETVMEIVKRCKN-LSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCK-ITDYAL 211
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
A+GR ++ +++ C ++D +A L ++ + C + E VE L + P
Sbjct: 212 IAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYP 271
Query: 547 KL 548
+
Sbjct: 272 HI 273
Score = 40.7 bits (91), Expect = 0.014
Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Query: 441 GGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKIN 500
G L++L L C+ I D ++ + + IE +++ CK+ITDQ + + L+ +
Sbjct: 193 GQNLKELYLVSCK-ITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLG 251
Query: 501 LDSCPSVSDISLKALADGCPLLTHVNV 527
L C V++++++ L P +T V
Sbjct: 252 LMRCDKVNEVTVEQLVQQYPHITFSTV 278
>BC126144-1|AAI26145.1| 303|Homo sapiens F-box and leucine-rich
repeat protein 17 protein.
Length = 303
Score = 72.1 bits (169), Expect = 5e-12
Identities = 33/111 (29%), Positives = 62/111 (55%), Gaps = 1/111 (0%)
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
+C G LR + R C+ + D S+ +A CP ++ +++ K+TD+ + LG +C +L+
Sbjct: 12 KCPGLLRYTAYR-CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKD 70
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
I+ C +SD + +A GC L + + + +T+ V+A A CP+L+
Sbjct: 71 IHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQ 121
Score = 62.5 bits (145), Expect = 4e-09
Identities = 31/100 (31%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+++ + + + D +K L C ++D++ +C KI+D+ + + C KLQ+I +
Sbjct: 42 LQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQE 101
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR 543
V+D S+KA A+ CP L +V C S+T GV L +
Sbjct: 102 NKLVTDQSVKAFAEHCPELQYVGFMGC-SVTSKGVIHLTK 140
Score = 59.3 bits (137), Expect = 4e-08
Identities = 27/95 (28%), Positives = 50/95 (52%)
Query: 455 IGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISLKA 514
+ D + LA CP + +CK+++D + A+ C LQK+++ + ++D LK
Sbjct: 1 MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
Query: 515 LADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L C L ++ C I++ G+ +A+GC KL+
Sbjct: 61 LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQ 95
Score = 50.0 bits (114), Expect = 2e-05
Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L L LR + + ++ + + C N+ LNL I D+ + + + L+++ L S
Sbjct: 144 LSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVS 203
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C ++D +L A+ + V+V WC+ IT+ G +A+ L+
Sbjct: 204 C-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLR 248
Score = 47.6 bits (108), Expect = 1e-04
Identities = 30/122 (24%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
+++ + I +RC L L+L I D ++ +A+ N+++L L CK ITD
Sbjct: 154 ELDNETVMEIVKRCKN-LSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCK-ITDYAL 211
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
A+GR ++ +++ C ++D +A L ++ + C + E VE L + P
Sbjct: 212 IAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYP 271
Query: 547 KL 548
+
Sbjct: 272 HI 273
Score = 40.7 bits (91), Expect = 0.014
Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Query: 441 GGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKIN 500
G L++L L C+ I D ++ + + IE +++ CK+ITDQ + + L+ +
Sbjct: 193 GQNLKELYLVSCK-ITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLG 251
Query: 501 LDSCPSVSDISLKALADGCPLLTHVNV 527
L C V++++++ L P +T V
Sbjct: 252 LMRCDKVNEVTVEQLVQQYPHITFSTV 278
>AK126722-1|BAC86658.1| 303|Homo sapiens protein ( Homo sapiens
cDNA FLJ44768 fis, clone BRACE3032631, highly similar
to Mus musculus F-box protein FBX13. ).
Length = 303
Score = 72.1 bits (169), Expect = 5e-12
Identities = 33/111 (29%), Positives = 62/111 (55%), Gaps = 1/111 (0%)
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
+C G LR + R C+ + D S+ +A CP ++ +++ K+TD+ + LG +C +L+
Sbjct: 12 KCPGLLRYTAYR-CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKD 70
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
I+ C +SD + +A GC L + + + +T+ V+A A CP+L+
Sbjct: 71 IHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQ 121
Score = 62.5 bits (145), Expect = 4e-09
Identities = 31/100 (31%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L+++ + + + D +K L C ++D++ +C KI+D+ + + C KLQ+I +
Sbjct: 42 LQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQE 101
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR 543
V+D S+KA A+ CP L +V C S+T GV L +
Sbjct: 102 NKLVTDQSVKAFAEHCPELQYVGFMGC-SVTSKGVIHLTK 140
Score = 59.3 bits (137), Expect = 4e-08
Identities = 27/95 (28%), Positives = 50/95 (52%)
Query: 455 IGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISLKA 514
+ D + LA CP + +CK+++D + A+ C LQK+++ + ++D LK
Sbjct: 1 MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
Query: 515 LADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L C L ++ C I++ G+ +A+GC KL+
Sbjct: 61 LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQ 95
Score = 50.0 bits (114), Expect = 2e-05
Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L L LR + + ++ + + C N+ LNL I D+ + + + L+++ L S
Sbjct: 144 LSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVS 203
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C ++D +L A+ + V+V WC+ IT+ G +A+ L+
Sbjct: 204 C-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLR 248
Score = 47.6 bits (108), Expect = 1e-04
Identities = 30/122 (24%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
Query: 427 DVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTC 486
+++ + I +RC L L+L I D ++ +A+ N+++L L CK ITD
Sbjct: 154 ELDNETVMEIVKRCKN-LSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCK-ITDYAL 211
Query: 487 QALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCP 546
A+GR ++ +++ C ++D +A L ++ + C + E VE L + P
Sbjct: 212 IAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYP 271
Query: 547 KL 548
+
Sbjct: 272 HI 273
Score = 40.7 bits (91), Expect = 0.014
Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Query: 441 GGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKIN 500
G L++L L C+ I D ++ + + IE +++ CK+ITDQ + + L+ +
Sbjct: 193 GQNLKELYLVSCK-ITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLG 251
Query: 501 LDSCPSVSDISLKALADGCPLLTHVNV 527
L C V++++++ L P +T V
Sbjct: 252 LMRCDKVNEVTVEQLVQQYPHITFSTV 278
>AY359239-1|AAR13263.1| 690|Homo sapiens F-box and leucine-rich
repeat protein 13 transcript variant 2 protein.
Length = 690
Score = 71.7 bits (168), Expect = 7e-12
Identities = 46/189 (24%), Positives = 95/189 (50%), Gaps = 5/189 (2%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQ 438
LP+ +L+I YL + + C QV+ W ++ S W ID + + I + Q
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 217
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
R + +L+ RGC + + ++++ C N+++LN++ C TD++ + + C +
Sbjct: 218 RWRLNVLRLNFRGC-LLRPKTFRSVSH-CRNLQELNVSDCPTFTDESMRHISEGCPGVLC 275
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE--ALARGCPKLKSFICKGK 556
+NL S ++++ +++ L L ++++++C+ T+ G++ L GC KL G
Sbjct: 276 LNL-SNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGC 334
Query: 557 PRESVPRLR 565
+ SV R
Sbjct: 335 TQVSVQGFR 343
Score = 54.8 bits (126), Expect = 8e-07
Identities = 52/214 (24%), Positives = 86/214 (40%), Gaps = 26/214 (12%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
FT+E HI+ P L L +L ++ +L N Q + L +R
Sbjct: 258 FTDESMRHISEGCPGVLCL---------NLSNTTITNRTMRLLPRHFHNLQNLSLAYCRR 308
Query: 427 DVE-GPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQT 485
+ G N+ C + L L GC + + +A SC I L +N +TD
Sbjct: 309 FTDKGLQYLNLGNGCHKLI-YLDLSGCTQVSVQGFRYIANSCTGIMHLTINDMPTLTDNC 367
Query: 486 CQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGC 545
+AL +CS++ + P +SD + +AL+ C L + + +T++ + + +
Sbjct: 368 VKALVEKCSRITSLVFTGAPHISDCTFRALS-ACK-LRKIRFEGNKRVTDASFKFIDKNY 425
Query: 546 PKLKSFI---CKGKPRESVPRLRIDDSGIESLGP 576
P L CKG I DS + SL P
Sbjct: 426 PNLSHIYMADCKG----------ITDSSLRSLSP 449
Score = 49.2 bits (112), Expect = 4e-05
Identities = 38/139 (27%), Positives = 70/139 (50%), Gaps = 13/139 (9%)
Query: 402 VSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMK 461
+S L + L+ +N RI ++ ++GP S R +R+L+L C + D S+
Sbjct: 447 LSPLKQLTVLNLANCVRIGDMGLKQFLDGPA----SMR----IRELNLSNCVRLSDASVM 498
Query: 462 TLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLD-SCPSVSDISLKALADGCP 520
L++ CPN+ L+L C+ + T Q +G + +++D S +S+ L L+
Sbjct: 499 KLSERCPNLNYLSLRNCEHL---TAQGIGYIVNIFSLVSIDLSGTDISNEGLNVLSRH-K 554
Query: 521 LLTHVNVSWCQSITESGVE 539
L ++VS C IT+ G++
Sbjct: 555 KLKELSVSECYRITDDGIQ 573
Score = 41.9 bits (94), Expect = 0.006
Identities = 44/189 (23%), Positives = 84/189 (44%), Gaps = 16/189 (8%)
Query: 388 LSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVE--GPVIENISQRCGGFLR 445
L L V++L C ++ + LDG RI V + +S+RC L
Sbjct: 450 LKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPN-LN 508
Query: 446 QLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCP 505
LSLR CE + + + ++ ++L+ I+++ L R KL+++++ C
Sbjct: 509 YLSLRNCEHLTAQGIGYIVNIF-SLVSIDLSGTD-ISNEGLNVLSRH-KKLKELSVSECY 565
Query: 506 -------SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPK---LKSFICKG 555
++D +++ L+ C L +++S C +T+ +E L GC + LK C
Sbjct: 566 RITDDGIQITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTN 625
Query: 556 KPRESVPRL 564
+E+ R+
Sbjct: 626 ISKEAAQRM 634
>BC031285-1|AAH31285.1| 707|Homo sapiens FBXL13 protein protein.
Length = 707
Score = 71.3 bits (167), Expect = 9e-12
Identities = 46/189 (24%), Positives = 95/189 (50%), Gaps = 5/189 (2%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQ 438
LP+ +L+I YL + + C QV+ W ++ S W ID + + I + Q
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 217
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
R + +L+ RGC + + ++++ C N+++LN++ C TD++ + + C +
Sbjct: 218 RWRLNVLRLNFRGC-LLRPKTFRSVSH-CRNLQELNVSDCPTFTDESMRHISEGCPGVLC 275
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE--ALARGCPKLKSFICKGK 556
+NL S ++++ +++ L L ++++++C+ T+ G++ L GC KL G
Sbjct: 276 LNL-SNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGC 334
Query: 557 PRESVPRLR 565
+ SV R
Sbjct: 335 TQISVQGFR 343
Score = 64.9 bits (151), Expect = 8e-10
Identities = 45/157 (28%), Positives = 81/157 (51%), Gaps = 13/157 (8%)
Query: 402 VSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMK 461
+S L + L+ +N RI ++ ++GP S R +R+L+L C + D S+
Sbjct: 447 LSPLKQLTVLNLANCVRIGDMGLKQFLDGPA----SMR----IRELNLSNCVRLSDASVM 498
Query: 462 TLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPL 521
L++ CPN+ L+L C+ + T Q +G + +++D S +DIS +A +
Sbjct: 499 KLSERCPNLNYLSLRNCEHL---TAQGIGYIVNIFSLVSIDL--SGTDISNEAFCKSSLI 553
Query: 522 LTHVNVSWCQSITESGVEALARGCPKLKSFICKGKPR 558
L H++VS+C +++ ++ALA C L S G P+
Sbjct: 554 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPK 590
Score = 58.4 bits (135), Expect = 7e-08
Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L L + C + D +K LA C N+ L++ C KITD + L +C L +++
Sbjct: 554 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISG 613
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKGKPR 558
C ++D L+ L GC L + + +C +I++ + ++ + + + G PR
Sbjct: 614 CVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMSSKVQQ-QEYNTNGPPR 667
Score = 57.6 bits (133), Expect = 1e-07
Identities = 48/185 (25%), Positives = 83/185 (44%), Gaps = 24/185 (12%)
Query: 388 LSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVE--GPVIENISQRCGGFLR 445
L L V++L C ++ + LDG RI V + +S+RC L
Sbjct: 450 LKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPN-LN 508
Query: 446 QLSLRGCE-----SIG----------------DGSMKTLAQSCPNIEDLNLNKCKKITDQ 484
LSLR CE IG D S + +S +E L+++ C +++D
Sbjct: 509 YLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEAFCKSSLILEHLDVSYCSQLSDM 568
Query: 485 TCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARG 544
+AL C L +++ CP ++D +++ L+ C L +++S C +T+ +E L G
Sbjct: 569 IIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIG 628
Query: 545 CPKLK 549
C +L+
Sbjct: 629 CKQLR 633
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 26/214 (12%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
FT+E HI+ P L L +L ++ +L N Q + L +R
Sbjct: 258 FTDESMRHISEGCPGVLCL---------NLSNTTITNRTMRLLPRHFHNLQNLSLAYCRR 308
Query: 427 DVE-GPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQT 485
+ G N+ C + L L GC I + +A SC I L +N +TD
Sbjct: 309 FTDKGLQYLNLGNGCHKLI-YLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNC 367
Query: 486 CQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGC 545
+AL +CS++ + P +SD + +AL+ C L + + +T++ + + +
Sbjct: 368 VKALVEKCSRITSLVFTGAPHISDCTFRALS-ACK-LRKIRFEGNKRVTDASFKFIDKNY 425
Query: 546 PKLKSFI---CKGKPRESVPRLRIDDSGIESLGP 576
P L CKG I DS + SL P
Sbjct: 426 PNLSHIYMADCKG----------ITDSSLRSLSP 449
>BC026121-1|AAH26121.1| 684|Homo sapiens FBXL13 protein protein.
Length = 684
Score = 71.3 bits (167), Expect = 9e-12
Identities = 46/189 (24%), Positives = 95/189 (50%), Gaps = 5/189 (2%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQ 438
LP+ +L+I YL + + C QV+ W ++ S W ID + + I + Q
Sbjct: 248 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 307
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
R + +L+ RGC + + ++++ C N+++LN++ C TD++ + + C +
Sbjct: 308 RWRLNVLRLNFRGC-LLRPKTFRSVSH-CRNLQELNVSDCPTFTDESMRHISEGCPGVLC 365
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE--ALARGCPKLKSFICKGK 556
+NL S ++++ +++ L L ++++++C+ T+ G++ L GC KL G
Sbjct: 366 LNL-SNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGC 424
Query: 557 PRESVPRLR 565
+ SV R
Sbjct: 425 TQISVQGFR 433
Score = 58.4 bits (135), Expect = 7e-08
Identities = 31/107 (28%), Positives = 57/107 (53%), Gaps = 3/107 (2%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
LR++ G + + D S K + ++ PN+ + + CK ITD + ++L +L +NL +
Sbjct: 492 LRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSP-LKQLTVLNLAN 550
Query: 504 CPSVSDISLKALADG--CPLLTHVNVSWCQSITESGVEALARGCPKL 548
C + D+ LK DG + +N+S C ++++ V L+ CP L
Sbjct: 551 CVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNL 597
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 26/214 (12%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
FT+E HI+ P L L +L ++ +L N Q + L +R
Sbjct: 348 FTDESMRHISEGCPGVLCL---------NLSNTTITNRTMRLLPRHFHNLQNLSLAYCRR 398
Query: 427 DVE-GPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQT 485
+ G N+ C + L L GC I + +A SC I L +N +TD
Sbjct: 399 FTDKGLQYLNLGNGCHKLI-YLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNC 457
Query: 486 CQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGC 545
+AL +CS++ + P +SD + +AL+ C L + + +T++ + + +
Sbjct: 458 VKALVEKCSRITSLVFTGAPHISDCTFRALS-ACK-LRKIRFEGNKRVTDASFKFIDKNY 515
Query: 546 PKLKSFI---CKGKPRESVPRLRIDDSGIESLGP 576
P L CKG I DS + SL P
Sbjct: 516 PNLSHIYMADCKG----------ITDSSLRSLSP 539
Score = 49.2 bits (112), Expect = 4e-05
Identities = 38/139 (27%), Positives = 70/139 (50%), Gaps = 13/139 (9%)
Query: 402 VSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMK 461
+S L + L+ +N RI ++ ++GP S R +R+L+L C + D S+
Sbjct: 537 LSPLKQLTVLNLANCVRIGDMGLKQFLDGPA----SMR----IRELNLSNCVRLSDASVM 588
Query: 462 TLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLD-SCPSVSDISLKALADGCP 520
L++ CPN+ L+L C+ + T Q +G + +++D S +S+ L L+
Sbjct: 589 KLSERCPNLNYLSLRNCEHL---TAQGIGYIVNIFSLVSIDLSGTDISNEGLNVLSRH-K 644
Query: 521 LLTHVNVSWCQSITESGVE 539
L ++VS C IT+ G++
Sbjct: 645 KLKELSVSECYRITDDGIQ 663
>AK097537-1|BAC05092.1| 735|Homo sapiens protein ( Homo sapiens
cDNA FLJ40218 fis, clone TESTI2021599. ).
Length = 735
Score = 71.3 bits (167), Expect = 9e-12
Identities = 46/189 (24%), Positives = 95/189 (50%), Gaps = 5/189 (2%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQ 438
LP+ +L+I YL + + C QV+ W ++ S W ID + + I + Q
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 217
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
R + +L+ RGC + + ++++ C N+++LN++ C TD++ + + C +
Sbjct: 218 RWRLNVLRLNFRGC-LLRPKTFRSVSH-CRNLQELNVSDCPTFTDESMRHISEGCPGVLC 275
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE--ALARGCPKLKSFICKGK 556
+NL S ++++ +++ L L ++++++C+ T+ G++ L GC KL G
Sbjct: 276 LNL-SNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGC 334
Query: 557 PRESVPRLR 565
+ SV R
Sbjct: 335 TQISVQGFR 343
Score = 63.3 bits (147), Expect = 2e-09
Identities = 29/106 (27%), Positives = 60/106 (56%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L++LS+ C I D ++ +S +E L+++ C +++D +AL C L +++
Sbjct: 556 LKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAG 615
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
CP ++D +++ L+ C L +++S C +T+ +E L GC +L+
Sbjct: 616 CPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLR 661
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/99 (27%), Positives = 50/99 (50%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L L + C + D +K LA C N+ L++ C KITD + L +C L +++
Sbjct: 582 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISG 641
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
C ++D L+ L GC L + + +C +I++ + ++
Sbjct: 642 CVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMS 680
Score = 56.4 bits (130), Expect = 3e-07
Identities = 43/173 (24%), Positives = 81/173 (46%), Gaps = 6/173 (3%)
Query: 388 LSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVE--GPVIENISQRCGGFLR 445
L L V++L C ++ + LDG RI V + +S+RC L
Sbjct: 450 LKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPN-LN 508
Query: 446 QLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCP 505
LSLR CE + + + ++ ++L+ I+++ L R KL+++++ C
Sbjct: 509 YLSLRNCEHLTAQGIGYIVNIF-SLVSIDLSGTD-ISNEGLNVLSRH-KKLKELSVSECY 565
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKGKPR 558
++D ++A +L H++VS+C +++ ++ALA C L S G P+
Sbjct: 566 RITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPK 618
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 26/214 (12%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
FT+E HI+ P L L +L ++ +L N Q + L +R
Sbjct: 258 FTDESMRHISEGCPGVLCL---------NLSNTTITNRTMRLLPRHFHNLQNLSLAYCRR 308
Query: 427 DVE-GPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQT 485
+ G N+ C + L L GC I + +A SC I L +N +TD
Sbjct: 309 FTDKGLQYLNLGNGCHKLI-YLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNC 367
Query: 486 CQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGC 545
+AL +CS++ + P +SD + +AL+ C L + + +T++ + + +
Sbjct: 368 VKALVEKCSRITSLVFTGAPHISDCTFRALS-ACK-LRKIRFEGNKRVTDASFKFIDKNY 425
Query: 546 PKLKSFI---CKGKPRESVPRLRIDDSGIESLGP 576
P L CKG I DS + SL P
Sbjct: 426 PNLSHIYMADCKG----------ITDSSLRSLSP 449
>AY359238-1|AAR13262.1| 453|Homo sapiens F-box and leucine-rich
repeat protein 13 transcript variant 1 protein.
Length = 453
Score = 70.9 bits (166), Expect = 1e-11
Identities = 42/172 (24%), Positives = 90/172 (52%), Gaps = 5/172 (2%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQ 438
LP+ +L+I YL + + C QV+ W ++ S W ID + + I + Q
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 217
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
R + +L+ RGC + + ++++ C N+++LN++ C TD++ + + C +
Sbjct: 218 RWRLNVLRLNFRGC-LLRPKTFRSVSH-CRNLQELNVSDCPTFTDESMRHISEGCPGVLC 275
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE--ALARGCPKL 548
+NL S ++++ +++ L L ++++++C+ T+ G++ L GC KL
Sbjct: 276 LNL-SNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKL 326
Score = 59.7 bits (138), Expect = 3e-08
Identities = 36/119 (30%), Positives = 68/119 (57%), Gaps = 4/119 (3%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--G 490
+ +IS+ C G L L+L +I + +M+ L + N+++L+L C++ TD+ Q L G
Sbjct: 263 MRHISEGCPGVLC-LNLSNT-TITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLG 320
Query: 491 RRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C KL ++L C ++D +++ L+ C L +++S C +T+ +E L GC +L+
Sbjct: 321 NGCHKLIYLDLSGCTQITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLR 379
Score = 50.4 bits (115), Expect = 2e-05
Identities = 26/101 (25%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Query: 444 LRQLSLRGCESIGDGSMK--TLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINL 501
L+ LSL C D ++ L C + L+L+ C +ITD + L +C L +++
Sbjct: 298 LQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQITDSAMEMLSAKCHYLHILDI 357
Query: 502 DSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
C ++D L+ L GC L + + +C +I++ + ++
Sbjct: 358 SGCVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMS 398
>AK095387-1|BAC04540.1| 456|Homo sapiens protein ( Homo sapiens
cDNA FLJ38068 fis, clone CTONG2015358. ).
Length = 456
Score = 69.7 bits (163), Expect = 3e-11
Identities = 42/162 (25%), Positives = 80/162 (49%), Gaps = 4/162 (2%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQ 438
LP+ +L+I YL + + C QV+ W ++ S W ID + + I + Q
Sbjct: 85 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 144
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCSKL 496
R + +L+ RGC + + ++L+ + LNL C +I D + G ++
Sbjct: 145 RWRLNVLRLNFRGC-LLRPKTFRSLS-PLKQLTVLNLANCVRIGDMGLKQFLDGPASMRI 202
Query: 497 QKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGV 538
++NL +C +SD S+ L++ CP L ++++ C+ +T G+
Sbjct: 203 GELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGI 244
Score = 63.3 bits (147), Expect = 2e-09
Identities = 29/106 (27%), Positives = 60/106 (56%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L++LS+ C I D ++ +S +E L+++ C +++D +AL C L +++
Sbjct: 277 LKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAG 336
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
CP ++D +++ L+ C L +++S C +T+ +E L GC +L+
Sbjct: 337 CPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLR 382
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/99 (27%), Positives = 50/99 (50%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L L + C + D +K LA C N+ L++ C KITD + L +C L +++
Sbjct: 303 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISG 362
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
C ++D L+ L GC L + + +C +I++ + ++
Sbjct: 363 CVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMS 401
Score = 56.8 bits (131), Expect = 2e-07
Identities = 43/173 (24%), Positives = 81/173 (46%), Gaps = 6/173 (3%)
Query: 388 LSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVE--GPVIENISQRCGGFLR 445
L L V++L C ++ + LDG RI V + +S+RC L
Sbjct: 171 LKQLTVLNLANCVRIGDMGLKQFLDGPASMRIGELNLSNCVRLSDASVMKLSERCPN-LN 229
Query: 446 QLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCP 505
LSLR CE + + + ++ ++L+ I+++ L R KL+++++ C
Sbjct: 230 YLSLRNCEHLTAQGIGYIVNIF-SLVSIDLSGTD-ISNEGLNVLSRH-KKLKELSVSECY 286
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKGKPR 558
++D ++A +L H++VS+C +++ ++ALA C L S G P+
Sbjct: 287 RITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPK 339
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 68.9 bits (161), Expect = 5e-11
Identities = 31/93 (33%), Positives = 54/93 (58%), Gaps = 2/93 (2%)
Query: 163 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTI--KPDA 220
+P N + + + TW +E + G+VK +G+SNFN++QLE +L + + KP +
Sbjct: 10 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVS 69
Query: 221 IQIEVHLQNVQKEMVEFCQSEGVVVMGYSPFGS 253
Q+E H Q ++++FCQ +V+ YSP G+
Sbjct: 70 NQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 102
>BC067906-1|AAH67906.1| 213|Homo sapiens antagonist of mitotic exit
network 1 homolog (S. cerevisiae) protein.
Length = 213
Score = 67.3 bits (157), Expect = 1e-10
Identities = 38/127 (29%), Positives = 68/127 (53%), Gaps = 4/127 (3%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
I+ ++ C +L + SL+ C ++ D + LA +C ++ ++L C ITD + ALG+
Sbjct: 62 IKAVASSCS-YLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKN 120
Query: 493 CSKLQKINLDSCPSVSDISLKALADG--CPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
C LQ ++ S VSD + AL G L +++ C ++T+ VEA+ CP+++
Sbjct: 121 CPFLQCVDF-SATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRI 179
Query: 551 FICKGKP 557
+ G P
Sbjct: 180 LLFHGCP 186
Score = 66.9 bits (156), Expect = 2e-10
Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 454 SIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISLK 513
S+ +K +A SC + + +L +C +TD+ AL C L+ I+L C S++D+SL
Sbjct: 56 SVTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLH 115
Query: 514 ALADGCPLLTHVNVSWCQSITESGVEALARG-CPK 547
AL CP L V+ S Q +++SGV AL G C K
Sbjct: 116 ALGKNCPFLQCVDFSATQ-VSDSGVIALVSGPCAK 149
Score = 64.9 bits (151), Expect = 8e-10
Identities = 40/127 (31%), Positives = 71/127 (55%), Gaps = 7/127 (5%)
Query: 428 VEGPVIE-NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCK----KIT 482
++G + + NIS+ ++ L LR C+ I D ++ L+ +C ++ LNLN K +T
Sbjct: 1 MQGQITDSNISEILHPEVQTLDLRSCD-ISDAALLHLS-NCRKLKKLNLNASKGNRVSVT 58
Query: 483 DQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
+ +A+ CS L + +L C +++D + ALA C LL +++ C SIT+ + AL
Sbjct: 59 SEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALG 118
Query: 543 RGCPKLK 549
+ CP L+
Sbjct: 119 KNCPFLQ 125
Score = 47.2 bits (107), Expect = 2e-04
Identities = 32/110 (29%), Positives = 60/110 (54%), Gaps = 5/110 (4%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCSKLQKINL 501
L+ + L GC SI D S+ L ++CP ++ ++ + +++D AL G KL++I++
Sbjct: 98 LKIIDLGGCLSITDVSLHALGKNCPFLQCVDFS-ATQVSDSGVIALVSGPCAKKLEEIHM 156
Query: 502 DSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR--GCPKLK 549
C +++D +++A+ CP + + C IT+ E L + G KLK
Sbjct: 157 GHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITDHSREVLEQLVGPNKLK 206
Score = 36.7 bits (81), Expect = 0.23
Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDV--EGPVIENISQRCGGFLRQLS 448
L ++ L C ++ + ++ AL G N + +F + VI +S C L ++
Sbjct: 98 LKIIDLGGCLSITDV-SLHAL-GKNCPFLQCVDFSATQVSDSGVIALVSGPCAKKLEEIH 155
Query: 449 LRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
+ C ++ DG+++ + CP I L + C ITD + + L
Sbjct: 156 MGHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITDHSREVL 196
Score = 35.1 bits (77), Expect = 0.71
Identities = 29/129 (22%), Positives = 59/129 (45%), Gaps = 4/129 (3%)
Query: 389 SYLDVVSLCRCAQVSKLWNI-LALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQL 447
SYL SL RC ++ + LAL+ + IDL + + + + C FL+ +
Sbjct: 70 SYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCL-SITDVSLHALGKNCP-FLQCV 127
Query: 448 SLRGCESIGDGSMKTLAQSCPN-IEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPS 506
+ G + ++ C +E++++ C +TD +A+ C +++ + CP
Sbjct: 128 DFSATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCPL 187
Query: 507 VSDISLKAL 515
++D S + L
Sbjct: 188 ITDHSREVL 196
>BC045831-1|AAH45831.2| 215|Homo sapiens AMN1 protein protein.
Length = 215
Score = 67.3 bits (157), Expect = 1e-10
Identities = 38/127 (29%), Positives = 68/127 (53%), Gaps = 4/127 (3%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
I+ ++ C +L + SL+ C ++ D + LA +C ++ ++L C ITD + ALG+
Sbjct: 64 IKAVASSCS-YLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKN 122
Query: 493 CSKLQKINLDSCPSVSDISLKALADG--CPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
C LQ ++ S VSD + AL G L +++ C ++T+ VEA+ CP+++
Sbjct: 123 CPFLQCVDF-SATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRI 181
Query: 551 FICKGKP 557
+ G P
Sbjct: 182 LLFHGCP 188
Score = 66.9 bits (156), Expect = 2e-10
Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 454 SIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISLK 513
S+ +K +A SC + + +L +C +TD+ AL C L+ I+L C S++D+SL
Sbjct: 58 SVTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLH 117
Query: 514 ALADGCPLLTHVNVSWCQSITESGVEALARG-CPK 547
AL CP L V+ S Q +++SGV AL G C K
Sbjct: 118 ALGKNCPFLQCVDFSATQ-VSDSGVIALVSGPCAK 151
Score = 64.9 bits (151), Expect = 8e-10
Identities = 40/127 (31%), Positives = 71/127 (55%), Gaps = 7/127 (5%)
Query: 428 VEGPVIE-NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCK----KIT 482
++G + + NIS+ ++ L LR C+ I D ++ L+ +C ++ LNLN K +T
Sbjct: 3 MQGQITDSNISEILHPEVQTLDLRSCD-ISDAALLHLS-NCRKLKKLNLNASKGNRVSVT 60
Query: 483 DQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
+ +A+ CS L + +L C +++D + ALA C LL +++ C SIT+ + AL
Sbjct: 61 SEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALG 120
Query: 543 RGCPKLK 549
+ CP L+
Sbjct: 121 KNCPFLQ 127
Score = 47.2 bits (107), Expect = 2e-04
Identities = 32/110 (29%), Positives = 60/110 (54%), Gaps = 5/110 (4%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCSKLQKINL 501
L+ + L GC SI D S+ L ++CP ++ ++ + +++D AL G KL++I++
Sbjct: 100 LKIIDLGGCLSITDVSLHALGKNCPFLQCVDFS-ATQVSDSGVIALVSGPCAKKLEEIHM 158
Query: 502 DSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR--GCPKLK 549
C +++D +++A+ CP + + C IT+ E L + G KLK
Sbjct: 159 GHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITDHSREVLEQLVGPNKLK 208
Score = 36.7 bits (81), Expect = 0.23
Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDV--EGPVIENISQRCGGFLRQLS 448
L ++ L C ++ + ++ AL G N + +F + VI +S C L ++
Sbjct: 100 LKIIDLGGCLSITDV-SLHAL-GKNCPFLQCVDFSATQVSDSGVIALVSGPCAKKLEEIH 157
Query: 449 LRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
+ C ++ DG+++ + CP I L + C ITD + + L
Sbjct: 158 MGHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITDHSREVL 198
Score = 35.1 bits (77), Expect = 0.71
Identities = 29/129 (22%), Positives = 59/129 (45%), Gaps = 4/129 (3%)
Query: 389 SYLDVVSLCRCAQVSKLWNI-LALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQL 447
SYL SL RC ++ + LAL+ + IDL + + + + C FL+ +
Sbjct: 72 SYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCL-SITDVSLHALGKNCP-FLQCV 129
Query: 448 SLRGCESIGDGSMKTLAQSCPN-IEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPS 506
+ G + ++ C +E++++ C +TD +A+ C +++ + CP
Sbjct: 130 DFSATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCPL 189
Query: 507 VSDISLKAL 515
++D S + L
Sbjct: 190 ITDHSREVL 198
>BC037897-1|AAH37897.3| 215|Homo sapiens AMN1 protein protein.
Length = 215
Score = 67.3 bits (157), Expect = 1e-10
Identities = 38/127 (29%), Positives = 68/127 (53%), Gaps = 4/127 (3%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
I+ ++ C +L + SL+ C ++ D + LA +C ++ ++L C ITD + ALG+
Sbjct: 64 IKAVASSCS-YLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKN 122
Query: 493 CSKLQKINLDSCPSVSDISLKALADG--CPLLTHVNVSWCQSITESGVEALARGCPKLKS 550
C LQ ++ S VSD + AL G L +++ C ++T+ VEA+ CP+++
Sbjct: 123 CPFLQCVDF-SATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRI 181
Query: 551 FICKGKP 557
+ G P
Sbjct: 182 LLFHGCP 188
Score = 66.9 bits (156), Expect = 2e-10
Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 454 SIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISLK 513
S+ +K +A SC + + +L +C +TD+ AL C L+ I+L C S++D+SL
Sbjct: 58 SVTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLH 117
Query: 514 ALADGCPLLTHVNVSWCQSITESGVEALARG-CPK 547
AL CP L V+ S Q +++SGV AL G C K
Sbjct: 118 ALGKNCPFLQCVDFSATQ-VSDSGVIALVSGPCAK 151
Score = 64.9 bits (151), Expect = 8e-10
Identities = 40/127 (31%), Positives = 71/127 (55%), Gaps = 7/127 (5%)
Query: 428 VEGPVIE-NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCK----KIT 482
++G + + NIS+ ++ L LR C+ I D ++ L+ +C ++ LNLN K +T
Sbjct: 3 MQGQITDSNISEILHPEVQTLDLRSCD-ISDAALLHLS-NCRKLKKLNLNASKGNRVSVT 60
Query: 483 DQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
+ +A+ CS L + +L C +++D + ALA C LL +++ C SIT+ + AL
Sbjct: 61 SEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALG 120
Query: 543 RGCPKLK 549
+ CP L+
Sbjct: 121 KNCPFLQ 127
Score = 47.2 bits (107), Expect = 2e-04
Identities = 32/110 (29%), Positives = 60/110 (54%), Gaps = 5/110 (4%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCSKLQKINL 501
L+ + L GC SI D S+ L ++CP ++ ++ + +++D AL G KL++I++
Sbjct: 100 LKIIDLGGCLSITDVSLHALGKNCPFLQCVDFS-ATQVSDSGVIALVSGPCAKKLEEIHM 158
Query: 502 DSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR--GCPKLK 549
C +++D +++A+ CP + + C IT+ E L + G KLK
Sbjct: 159 GHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITDHSREVLEQLVGPNKLK 208
Score = 36.7 bits (81), Expect = 0.23
Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Query: 391 LDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDV--EGPVIENISQRCGGFLRQLS 448
L ++ L C ++ + ++ AL G N + +F + VI +S C L ++
Sbjct: 100 LKIIDLGGCLSITDV-SLHAL-GKNCPFLQCVDFSATQVSDSGVIALVSGPCAKKLEEIH 157
Query: 449 LRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
+ C ++ DG+++ + CP I L + C ITD + + L
Sbjct: 158 MGHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITDHSREVL 198
Score = 35.1 bits (77), Expect = 0.71
Identities = 29/129 (22%), Positives = 59/129 (45%), Gaps = 4/129 (3%)
Query: 389 SYLDVVSLCRCAQVSKLWNI-LALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQL 447
SYL SL RC ++ + LAL+ + IDL + + + + C FL+ +
Sbjct: 72 SYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCL-SITDVSLHALGKNCP-FLQCV 129
Query: 448 SLRGCESIGDGSMKTLAQSCPN-IEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPS 506
+ G + ++ C +E++++ C +TD +A+ C +++ + CP
Sbjct: 130 DFSATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCPL 189
Query: 507 VSDISLKAL 515
++D S + L
Sbjct: 190 ITDHSREVL 198
>AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-related
protein protein.
Length = 85
Score = 65.7 bits (153), Expect = 4e-10
Identities = 32/82 (39%), Positives = 49/82 (59%)
Query: 270 PVLSSIAQKYGKTTPQIVLRWQIERKVVPIPKTVNPKRLEENINIFDFTLTPDEVEKING 329
P + IA K+ KT Q+++R+ I+R V+ IPK+V P R+ ENI +FDF L+ +E+ I
Sbjct: 1 PKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILS 60
Query: 330 FDTHTRYTLPSFWQNHPYYPFD 351
F+ + R + YPFD
Sbjct: 61 FNRNWRACNVLQSSHLEDYPFD 82
>U33761-1|AAC50242.1| 435|Homo sapiens cyclin A/CDK2-associated p45
protein.
Length = 435
Score = 63.7 bits (148), Expect = 2e-09
Identities = 54/176 (30%), Positives = 76/176 (43%), Gaps = 16/176 (9%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLF--EFQRDVEGPVIEN- 435
LP ELLL I S L + L + + V K W LA D S WQ +DL DV G ++
Sbjct: 112 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQG 171
Query: 436 -ISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLN--LNKCKK---------ITD 483
I+ RC L S L+ S + L+ L++C K ++D
Sbjct: 172 VIAFRCPRSFMDQPLAEHFSPFRVQDMDLSNSVIEVSTLHGILSQCSKLQNLSLELRLSD 231
Query: 484 QTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
L + S L ++NL CP L+ CP L +N+SWC + TE V+
Sbjct: 232 PIVNTLAKN-SNLVRLNLPGCPGFPKFPLQTFLSSCPRLDELNLSWCFNFTEKHVQ 286
>BC007441-1|AAH07441.1| 410|Homo sapiens S-phase kinase-associated
protein 2 (p45) protein.
Length = 410
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLF--EFQRDVEGPVIEN- 435
LP ELLL I S L + L + + V K W LA D S WQ +DL DV G ++
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQG 159
Query: 436 -ISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLN--LNKCKKITDQTCQALG-- 490
I+ RC L S L+ S + L+ L++C K+ + + + L
Sbjct: 160 VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLS 219
Query: 491 -------RRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
+ S L ++NL C S+ +L+ L C L +N+SWC TE V+
Sbjct: 220 DPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQ 275
>BC001441-1|AAH01441.1| 410|Homo sapiens S-phase kinase-associated
protein 2 (p45) protein.
Length = 410
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLF--EFQRDVEGPVIEN- 435
LP ELLL I S L + L + + V K W LA D S WQ +DL DV G ++
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQG 159
Query: 436 -ISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLN--LNKCKKITDQTCQALG-- 490
I+ RC L S L+ S + L+ L++C K+ + + + L
Sbjct: 160 VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLS 219
Query: 491 -------RRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
+ S L ++NL C S+ +L+ L C L +N+SWC TE V+
Sbjct: 220 DPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQ 275
>AY029177-1|AAK31593.1| 424|Homo sapiens F-box protein SKP2
protein.
Length = 424
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLF--EFQRDVEGPVIEN- 435
LP ELLL I S L + L + + V K W LA D S WQ +DL DV G ++
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQG 159
Query: 436 -ISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLN--LNKCKKITDQTCQALG-- 490
I+ RC L S L+ S + L+ L++C K+ + + + L
Sbjct: 160 VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLS 219
Query: 491 -------RRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
+ S L ++NL C S+ +L+ L C L +N+SWC TE V+
Sbjct: 220 DPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQ 275
>AB050981-1|BAB87202.1| 442|Homo sapiens SKP2-like protein type
gamma protein.
Length = 442
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLF--EFQRDVEGPVIEN- 435
LP ELLL I S L + L + + V K W LA D S WQ +DL DV G ++
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQG 159
Query: 436 -ISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLN--LNKCKKITDQTCQALG-- 490
I+ RC L S L+ S + L+ L++C K+ + + + L
Sbjct: 160 VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLS 219
Query: 491 -------RRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
+ S L ++NL C S+ +L+ L C L +N+SWC TE V+
Sbjct: 220 DPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQ 275
>AB050980-1|BAB87201.1| 410|Homo sapiens SKP2-like protein type
beta protein.
Length = 410
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLF--EFQRDVEGPVIEN- 435
LP ELLL I S L + L + + V K W LA D S WQ +DL DV G ++
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQG 159
Query: 436 -ISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLN--LNKCKKITDQTCQALG-- 490
I+ RC L S L+ S + L+ L++C K+ + + + L
Sbjct: 160 VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLS 219
Query: 491 -------RRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
+ S L ++NL C S+ +L+ L C L +N+SWC TE V+
Sbjct: 220 DPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQ 275
>AB050979-1|BAB87200.1| 424|Homo sapiens SKP2-like protein type
alpha protein.
Length = 424
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLF--EFQRDVEGPVIEN- 435
LP ELLL I S L + L + + V K W LA D S WQ +DL DV G ++
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQG 159
Query: 436 -ISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLN--LNKCKKITDQTCQALG-- 490
I+ RC L S L+ S + L+ L++C K+ + + + L
Sbjct: 160 VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLS 219
Query: 491 -------RRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
+ S L ++NL C S+ +L+ L C L +N+SWC TE V+
Sbjct: 220 DPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQ 275
>BC020575-1|AAH20575.2| 247|Homo sapiens FBXL13 protein protein.
Length = 247
Score = 63.3 bits (147), Expect = 2e-09
Identities = 29/106 (27%), Positives = 60/106 (56%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L++LS+ C I D ++ +S +E L+++ C +++D +AL C L +++
Sbjct: 68 LKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAG 127
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
CP ++D +++ L+ C L +++S C +T+ +E L GC +L+
Sbjct: 128 CPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLR 173
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/99 (27%), Positives = 50/99 (50%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L L + C + D +K LA C N+ L++ C KITD + L +C L +++
Sbjct: 94 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISG 153
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
C ++D L+ L GC L + + +C +I++ + ++
Sbjct: 154 CVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMS 192
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/126 (25%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 433 IENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
+ +S+RC L LSLR CE + + + ++ ++L+ I+++ L R
Sbjct: 9 VMKLSERCPN-LNYLSLRNCEHLTAQGIGYIVNIF-SLVSIDLSGTD-ISNEGLNVLSRH 65
Query: 493 CSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFI 552
KL+++++ C ++D ++A +L H++VS+C +++ ++ALA C L S
Sbjct: 66 -KKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLS 124
Query: 553 CKGKPR 558
G P+
Sbjct: 125 IAGCPK 130
>BC020572-1|AAH20572.2| 569|Homo sapiens FBXL13 protein protein.
Length = 569
Score = 63.3 bits (147), Expect = 2e-09
Identities = 42/178 (23%), Positives = 88/178 (49%), Gaps = 5/178 (2%)
Query: 390 YLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSL 449
YL + + C QV+ W ++ S W ID + + I + QR + +L+
Sbjct: 3 YLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQRWRLNVLRLNF 62
Query: 450 RGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSD 509
RGC + + ++++ C N+++LN++ C TD++ + + C + +NL S ++++
Sbjct: 63 RGC-LLRPKTFRSVSH-CRNLQELNVSDCPTFTDESMRHISEGCPGVLCLNL-SNTTITN 119
Query: 510 ISLKALADGCPLLTHVNVSWCQSITESGVE--ALARGCPKLKSFICKGKPRESVPRLR 565
+++ L L ++++++C+ T+ G++ L GC KL G + SV R
Sbjct: 120 RTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFR 177
Score = 63.3 bits (147), Expect = 2e-09
Identities = 29/106 (27%), Positives = 60/106 (56%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L++LS+ C I D ++ +S +E L+++ C +++D +AL C L +++
Sbjct: 390 LKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAG 449
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
CP ++D +++ L+ C L +++S C +T+ +E L GC +L+
Sbjct: 450 CPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLR 495
Score = 57.6 bits (133), Expect = 1e-07
Identities = 27/99 (27%), Positives = 50/99 (50%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L L + C + D +K LA C N+ L++ C KITD + L +C L +++
Sbjct: 416 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISG 475
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
C ++D L+ L GC L + + +C +I++ + ++
Sbjct: 476 CVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMS 514
Score = 56.4 bits (130), Expect = 3e-07
Identities = 43/173 (24%), Positives = 81/173 (46%), Gaps = 6/173 (3%)
Query: 388 LSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVE--GPVIENISQRCGGFLR 445
L L V++L C ++ + LDG RI V + +S+RC L
Sbjct: 284 LKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPN-LN 342
Query: 446 QLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCP 505
LSLR CE + + + ++ ++L+ I+++ L R KL+++++ C
Sbjct: 343 YLSLRNCEHLTAQGIGYIVNIF-SLVSIDLSGTD-ISNEGLNVLSRH-KKLKELSVSECY 399
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKGKPR 558
++D ++A +L H++VS+C +++ ++ALA C L S G P+
Sbjct: 400 RITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPK 452
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 26/214 (12%)
Query: 367 FTNEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQR 426
FT+E HI+ P L L +L ++ +L N Q + L +R
Sbjct: 92 FTDESMRHISEGCPGVLCL---------NLSNTTITNRTMRLLPRHFHNLQNLSLAYCRR 142
Query: 427 DVE-GPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQT 485
+ G N+ C + L L GC I + +A SC I L +N +TD
Sbjct: 143 FTDKGLQYLNLGNGCHKLI-YLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNC 201
Query: 486 CQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGC 545
+AL +CS++ + P +SD + +AL+ C L + + +T++ + + +
Sbjct: 202 VKALVEKCSRITSLVFTGAPHISDCTFRALS-ACK-LRKIRFEGNKRVTDASFKFIDKNY 259
Query: 546 PKLKSFI---CKGKPRESVPRLRIDDSGIESLGP 576
P L CKG I DS + SL P
Sbjct: 260 PNLSHIYMADCKG----------ITDSSLRSLSP 283
>AL121928-7|CAI12520.1| 208|Homo sapiens novel protein protein.
Length = 208
Score = 62.1 bits (144), Expect = 5e-09
Identities = 38/163 (23%), Positives = 83/163 (50%), Gaps = 3/163 (1%)
Query: 383 LLLRILSYLDVVSLCRCAQVSKLW-NILALDGSNWQRIDLFEFQRDVEGPVIENISQRCG 441
LL +L+ + + L R +VS+ + +++ L + +R D + + + + +
Sbjct: 28 LLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAE 87
Query: 442 GFLRQLSLRGC-ESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKIN 500
G L++L+L C E + D + + P + + L C +++ + AL C +LQ+++
Sbjct: 88 G-LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLS 146
Query: 501 LDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR 543
L C V ++L+ LAD CP L ++++ C+ + + + LA+
Sbjct: 147 LAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQ 189
Score = 45.2 bits (102), Expect = 7e-04
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Query: 459 SMKTLAQSCPNIEDLNLNKCKK-ITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALAD 517
++ L + +++L L C + ++D+ + R +L+ + L C +S +L ALA+
Sbjct: 78 ALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAE 137
Query: 518 GCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
GCP L ++++ C + + LA CP L+
Sbjct: 138 GCPRLQRLSLAHCDWVDGLALRGLADRCPALE 169
Score = 40.7 bits (91), Expect = 0.014
Identities = 21/67 (31%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALG-RRCSKLQKINLD 502
L++LSL C+ + +++ LA CP +E+L+L C+++ D+ L RR + L+ ++L
Sbjct: 142 LQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLA 201
Query: 503 SCPSVSD 509
+V D
Sbjct: 202 VNANVGD 208
>AL121928-6|CAI12519.1| 203|Homo sapiens novel protein protein.
Length = 203
Score = 62.1 bits (144), Expect = 5e-09
Identities = 38/163 (23%), Positives = 83/163 (50%), Gaps = 3/163 (1%)
Query: 383 LLLRILSYLDVVSLCRCAQVSKLW-NILALDGSNWQRIDLFEFQRDVEGPVIENISQRCG 441
LL +L+ + + L R +VS+ + +++ L + +R D + + + + +
Sbjct: 28 LLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAE 87
Query: 442 GFLRQLSLRGC-ESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKIN 500
G L++L+L C E + D + + P + + L C +++ + AL C +LQ+++
Sbjct: 88 G-LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLS 146
Query: 501 LDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR 543
L C V ++L+ LAD CP L ++++ C+ + + + LA+
Sbjct: 147 LAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQ 189
Score = 45.2 bits (102), Expect = 7e-04
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Query: 459 SMKTLAQSCPNIEDLNLNKCKK-ITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALAD 517
++ L + +++L L C + ++D+ + R +L+ + L C +S +L ALA+
Sbjct: 78 ALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAE 137
Query: 518 GCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
GCP L ++++ C + + LA CP L+
Sbjct: 138 GCPRLQRLSLAHCDWVDGLALRGLADRCPALE 169
Score = 39.5 bits (88), Expect = 0.033
Identities = 19/59 (32%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALG-RRCSKLQKINL 501
L++LSL C+ + +++ LA CP +E+L+L C+++ D+ L RR + L+ ++L
Sbjct: 142 LQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSL 200
>AL121928-5|CAI12518.1| 190|Homo sapiens novel protein protein.
Length = 190
Score = 62.1 bits (144), Expect = 5e-09
Identities = 38/163 (23%), Positives = 83/163 (50%), Gaps = 3/163 (1%)
Query: 383 LLLRILSYLDVVSLCRCAQVSKLW-NILALDGSNWQRIDLFEFQRDVEGPVIENISQRCG 441
LL +L+ + + L R +VS+ + +++ L + +R D + + + + +
Sbjct: 28 LLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAE 87
Query: 442 GFLRQLSLRGC-ESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKIN 500
G L++L+L C E + D + + P + + L C +++ + AL C +LQ+++
Sbjct: 88 G-LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLS 146
Query: 501 LDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALAR 543
L C V ++L+ LAD CP L ++++ C+ + + + LA+
Sbjct: 147 LAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQ 189
Score = 45.2 bits (102), Expect = 7e-04
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Query: 459 SMKTLAQSCPNIEDLNLNKCKK-ITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALAD 517
++ L + +++L L C + ++D+ + R +L+ + L C +S +L ALA+
Sbjct: 78 ALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAE 137
Query: 518 GCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
GCP L ++++ C + + LA CP L+
Sbjct: 138 GCPRLQRLSLAHCDWVDGLALRGLADRCPALE 169
Score = 39.1 bits (87), Expect = 0.044
Identities = 16/49 (32%), Positives = 31/49 (63%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRR 492
L++LSL C+ + +++ LA CP +E+L+L C+++ D+ L +R
Sbjct: 142 LQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQR 190
>BC091484-1|AAH91484.1| 621|Homo sapiens FBXL4 protein protein.
Length = 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 55/227 (24%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
KLP EL+ IL++L + LCR AQ KL + D + ++L + ++ +E +
Sbjct: 282 KLPYELIQLILNHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQ 341
Query: 438 QRC-------------------GGFLRQLSLRGCESI----------GDGSMKTLAQSCP 468
RC GF R L + G E + + ++ +++ CP
Sbjct: 342 SRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCP 401
Query: 469 NIEDLNLNKCKKITDQTCQALGRR------------------------CSKLQKINLDSC 504
N++ LNL+ C K+ Q + + CS+LQ ++L SC
Sbjct: 402 NLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSC 461
Query: 505 PSVSDISLKALADG--CPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+ D + A G C L +++ C++ITE+G+ LA GCP L+
Sbjct: 462 VMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLE 508
Score = 59.7 bits (138), Expect = 3e-08
Identities = 47/179 (26%), Positives = 84/179 (46%), Gaps = 10/179 (5%)
Query: 378 KLPKELLLRILSY---LDVVSLCRCAQVSKLWNILALDGSNWQRI---DLFEFQRDVEGP 431
K+ + LL IL++ L +SL C + I ++ G+ +++ DL+ + E
Sbjct: 437 KVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENG 496
Query: 432 VIENISQRCGGFLRQLSLRGCESI--GDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
+ E ++ C L +L L C ++ G LA PN++ L L + + D L
Sbjct: 497 IAE-LASGCP-LLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDEL 554
Query: 490 GRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
C++LQ++++ VS SL+ L + C L+ ++VS+C I V L PK+
Sbjct: 555 ACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKV 613
>BC055010-1|AAH55010.1| 621|Homo sapiens F-box and leucine-rich
repeat protein 4 protein.
Length = 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 55/227 (24%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
KLP EL+ IL++L + LCR AQ KL + D + ++L + ++ +E +
Sbjct: 282 KLPYELIQLILNHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQ 341
Query: 438 QRC-------------------GGFLRQLSLRGCESI----------GDGSMKTLAQSCP 468
RC GF R L + G E + + ++ +++ CP
Sbjct: 342 SRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCP 401
Query: 469 NIEDLNLNKCKKITDQTCQALGRR------------------------CSKLQKINLDSC 504
N++ LNL+ C K+ Q + + CS+LQ ++L SC
Sbjct: 402 NLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSC 461
Query: 505 PSVSDISLKALADG--CPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+ D + A G C L +++ C++ITE+G+ LA GCP L+
Sbjct: 462 VMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLE 508
Score = 59.7 bits (138), Expect = 3e-08
Identities = 47/179 (26%), Positives = 84/179 (46%), Gaps = 10/179 (5%)
Query: 378 KLPKELLLRILSY---LDVVSLCRCAQVSKLWNILALDGSNWQRI---DLFEFQRDVEGP 431
K+ + LL IL++ L +SL C + I ++ G+ +++ DL+ + E
Sbjct: 437 KVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENG 496
Query: 432 VIENISQRCGGFLRQLSLRGCESI--GDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
+ E ++ C L +L L C ++ G LA PN++ L L + + D L
Sbjct: 497 IAE-LASGCP-LLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDEL 554
Query: 490 GRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
C++LQ++++ VS SL+ L + C L+ ++VS+C I V L PK+
Sbjct: 555 ACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKV 613
>BC018785-1|AAH18785.1| 223|Homo sapiens leucine rich repeat
containing 29 protein.
Length = 223
Score = 60.1 bits (139), Expect = 2e-08
Identities = 30/106 (28%), Positives = 53/106 (50%), Gaps = 1/106 (0%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L++L L C + D S+ + Q + L+L+ ++TD A+ R C L+ + L
Sbjct: 77 LQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +SD A P L H+N+S C + E ++A+ + C +L+
Sbjct: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLR 181
Score = 60.1 bits (139), Expect = 2e-08
Identities = 30/105 (28%), Positives = 53/105 (50%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
LRQLSL + D + +A+ CP++E L L+ C +++D+ +LQ +NL S
Sbjct: 102 LRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSS 161
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
C + + +L A+ C L ++V+ C I + V P++
Sbjct: 162 CSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVRRFQAQLPQV 206
Score = 53.6 bits (123), Expect = 2e-06
Identities = 35/148 (23%), Positives = 73/148 (49%), Gaps = 9/148 (6%)
Query: 380 PKELLLRILSYLDVVSLCRC--AQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
P L LR L LD+ + + A ++K+ L L +++ L + ++ ++
Sbjct: 69 PSLLTLRALQELDLTACSKLTDASLAKVLQFLQL-----RQLSLSLLPELTDNGLVA-VA 122
Query: 438 QRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQ 497
+ C L L+L C + D A S P ++ LNL+ C ++ +QT A+G+ C +L+
Sbjct: 123 RGCPS-LEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLR 181
Query: 498 KINLDSCPSVSDISLKALADGCPLLTHV 525
+++ +CP ++ +++ P ++ V
Sbjct: 182 VLDVATCPGINMAAVRRFQAQLPQVSCV 209
>AL022395-1|CAB37981.1| 621|Homo sapiens F-box and leucine-rich
repeat protein 4 protein.
Length = 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 55/227 (24%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
KLP EL+ IL++L + LCR AQ KL + D + ++L + ++ +E +
Sbjct: 282 KLPYELIQLILNHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQ 341
Query: 438 QRC-------------------GGFLRQLSLRGCESI----------GDGSMKTLAQSCP 468
RC GF R L + G E + + ++ +++ CP
Sbjct: 342 SRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCP 401
Query: 469 NIEDLNLNKCKKITDQTCQALGRR------------------------CSKLQKINLDSC 504
N++ LNL+ C K+ Q + + CS+LQ ++L SC
Sbjct: 402 NLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSC 461
Query: 505 PSVSDISLKALADG--CPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+ D + A G C L +++ C++ITE+G+ LA GCP L+
Sbjct: 462 VMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLE 508
Score = 59.7 bits (138), Expect = 3e-08
Identities = 47/179 (26%), Positives = 84/179 (46%), Gaps = 10/179 (5%)
Query: 378 KLPKELLLRILSY---LDVVSLCRCAQVSKLWNILALDGSNWQRI---DLFEFQRDVEGP 431
K+ + LL IL++ L +SL C + I ++ G+ +++ DL+ + E
Sbjct: 437 KVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENG 496
Query: 432 VIENISQRCGGFLRQLSLRGCESI--GDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
+ E ++ C L +L L C ++ G LA PN++ L L + + D L
Sbjct: 497 IAE-LASGCP-LLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDEL 554
Query: 490 GRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
C++LQ++++ VS SL+ L + C L+ ++VS+C I V L PK+
Sbjct: 555 ACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKV 613
>AF199355-1|AAF09247.1| 621|Homo sapiens F-box protein FBL5
protein.
Length = 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 55/227 (24%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
KLP EL+ IL++L + LCR AQ KL + D + ++L + ++ +E +
Sbjct: 282 KLPYELIQLILNHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQ 341
Query: 438 QRC-------------------GGFLRQLSLRGCESI----------GDGSMKTLAQSCP 468
RC GF R L + G E + + ++ +++ CP
Sbjct: 342 SRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCP 401
Query: 469 NIEDLNLNKCKKITDQTCQALGRR------------------------CSKLQKINLDSC 504
N++ LNL+ C K+ Q + + CS+LQ ++L SC
Sbjct: 402 NLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSC 461
Query: 505 PSVSDISLKALADG--CPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+ D + A G C L +++ C++ITE+G+ LA GCP L+
Sbjct: 462 VMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLE 508
Score = 59.7 bits (138), Expect = 3e-08
Identities = 47/179 (26%), Positives = 84/179 (46%), Gaps = 10/179 (5%)
Query: 378 KLPKELLLRILSY---LDVVSLCRCAQVSKLWNILALDGSNWQRI---DLFEFQRDVEGP 431
K+ + LL IL++ L +SL C + I ++ G+ +++ DL+ + E
Sbjct: 437 KVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENG 496
Query: 432 VIENISQRCGGFLRQLSLRGCESI--GDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
+ E ++ C L +L L C ++ G LA PN++ L L + + D L
Sbjct: 497 IAE-LASGCP-LLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDEL 554
Query: 490 GRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
C++LQ++++ VS SL+ L + C L+ ++VS+C I V L PK+
Sbjct: 555 ACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKV 613
>AF176701-1|AAF03701.1| 313|Homo sapiens F-box protein FBL9
protein.
Length = 313
Score = 60.1 bits (139), Expect = 2e-08
Identities = 30/106 (28%), Positives = 53/106 (50%), Gaps = 1/106 (0%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L++L L C + D S+ + Q + L+L+ ++TD A+ R C L+ + L
Sbjct: 167 LQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 225
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
C +SD A P L H+N+S C + E ++A+ + C +L+
Sbjct: 226 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLR 271
Score = 60.1 bits (139), Expect = 2e-08
Identities = 30/105 (28%), Positives = 53/105 (50%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
LRQLSL + D + +A+ CP++E L L+ C +++D+ +LQ +NL S
Sbjct: 192 LRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSS 251
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
C + + +L A+ C L ++V+ C I + V P++
Sbjct: 252 CSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVRRFQAQLPQV 296
Score = 53.6 bits (123), Expect = 2e-06
Identities = 35/148 (23%), Positives = 73/148 (49%), Gaps = 9/148 (6%)
Query: 380 PKELLLRILSYLDVVSLCRC--AQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
P L LR L LD+ + + A ++K+ L L +++ L + ++ ++
Sbjct: 159 PSLLTLRALQELDLTACSKLTDASLAKVLQFLQL-----RQLSLSLLPELTDNGLVA-VA 212
Query: 438 QRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQ 497
+ C L L+L C + D A S P ++ LNL+ C ++ +QT A+G+ C +L+
Sbjct: 213 RGCPS-LEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLR 271
Query: 498 KINLDSCPSVSDISLKALADGCPLLTHV 525
+++ +CP ++ +++ P ++ V
Sbjct: 272 VLDVATCPGINMAAVRRFQAQLPQVSCV 299
Score = 39.1 bits (87), Expect = 0.044
Identities = 16/47 (34%), Positives = 28/47 (59%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALG 490
L L L GC + DG++ +++ ++ L+L K +++TD C ALG
Sbjct: 49 LTSLDLSGCSELTDGALLAVSRGLRHLRRLSLGKLQRLTDAGCTALG 95
>AF176699-1|AAF03699.1| 621|Homo sapiens F-box protein FBL4
protein.
Length = 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 55/227 (24%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
KLP EL+ IL++L + LCR AQ KL + D + ++L + ++ +E +
Sbjct: 282 KLPYELIQLILNHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQ 341
Query: 438 QRC-------------------GGFLRQLSLRGCESI----------GDGSMKTLAQSCP 468
RC GF R L + G E + + ++ +++ CP
Sbjct: 342 SRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCP 401
Query: 469 NIEDLNLNKCKKITDQTCQALGRR------------------------CSKLQKINLDSC 504
N++ LNL+ C K+ Q + + CS+LQ ++L SC
Sbjct: 402 NLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSC 461
Query: 505 PSVSDISLKALADG--CPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+ D + A G C L +++ C++ITE+G+ LA GCP L+
Sbjct: 462 VMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLE 508
Score = 59.7 bits (138), Expect = 3e-08
Identities = 47/179 (26%), Positives = 84/179 (46%), Gaps = 10/179 (5%)
Query: 378 KLPKELLLRILSY---LDVVSLCRCAQVSKLWNILALDGSNWQRI---DLFEFQRDVEGP 431
K+ + LL IL++ L +SL C + I ++ G+ +++ DL+ + E
Sbjct: 437 KVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENG 496
Query: 432 VIENISQRCGGFLRQLSLRGCESI--GDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
+ E ++ C L +L L C ++ G LA PN++ L L + + D L
Sbjct: 497 IAE-LASGCP-LLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDEL 554
Query: 490 GRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
C++LQ++++ VS SL+ L + C L+ ++VS+C I V L PK+
Sbjct: 555 ACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKV 613
>AF174590-1|AAF04511.1| 621|Homo sapiens F-box protein Fbl4
protein.
Length = 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 55/227 (24%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
KLP EL+ IL++L + LCR AQ KL + D + ++L + ++ +E +
Sbjct: 282 KLPYELIQLILNHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQ 341
Query: 438 QRC-------------------GGFLRQLSLRGCESI----------GDGSMKTLAQSCP 468
RC GF R L + G E + + ++ +++ CP
Sbjct: 342 SRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCP 401
Query: 469 NIEDLNLNKCKKITDQTCQALGRR------------------------CSKLQKINLDSC 504
N++ LNL+ C K+ Q + + CS+LQ ++L SC
Sbjct: 402 NLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSC 461
Query: 505 PSVSDISLKALADG--CPLLTHVNVSWCQSITESGVEALARGCPKLK 549
+ D + A G C L +++ C++ITE+G+ LA GCP L+
Sbjct: 462 VMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLE 508
Score = 59.7 bits (138), Expect = 3e-08
Identities = 47/179 (26%), Positives = 84/179 (46%), Gaps = 10/179 (5%)
Query: 378 KLPKELLLRILSY---LDVVSLCRCAQVSKLWNILALDGSNWQRI---DLFEFQRDVEGP 431
K+ + LL IL++ L +SL C + I ++ G+ +++ DL+ + E
Sbjct: 437 KVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENG 496
Query: 432 VIENISQRCGGFLRQLSLRGCESI--GDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
+ E ++ C L +L L C ++ G LA PN++ L L + + D L
Sbjct: 497 IAE-LASGCP-LLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDEL 554
Query: 490 GRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
C++LQ++++ VS SL+ L + C L+ ++VS+C I V L PK+
Sbjct: 555 ACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKV 613
>AC005250-1|AAP22333.1| 325|Homo sapiens unknown protein.
Length = 325
Score = 56.4 bits (130), Expect = 3e-07
Identities = 27/94 (28%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 469 NIEDLNLNKCKKITDQTCQ--ALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVN 526
N+++L+L C++ TD+ Q LG C KL ++L C +S + +A+ C + H+
Sbjct: 4 NLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLT 63
Query: 527 VSWCQSITESGVEALARGCPKLKSFICKGKPRES 560
++ ++T++ V+AL C ++ S + G P S
Sbjct: 64 INDMPTLTDNCVKALVEKCSRITSLVFTGAPHIS 97
Score = 56.4 bits (130), Expect = 3e-07
Identities = 43/173 (24%), Positives = 81/173 (46%), Gaps = 6/173 (3%)
Query: 388 LSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVE--GPVIENISQRCGGFLR 445
L L V++L C ++ + LDG RI V + +S+RC L
Sbjct: 157 LKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPN-LN 215
Query: 446 QLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCP 505
LSLR CE + + + ++ ++L+ I+++ L R KL+++++ C
Sbjct: 216 YLSLRNCEHLTAQGIGYIVNIF-SLVSIDLSGTD-ISNEGLNVLSRH-KKLKELSVSECY 272
Query: 506 SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKGKPR 558
++D ++A +L H++VS+C +++ ++ALA C L S G P+
Sbjct: 273 RITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPK 325
Score = 52.4 bits (120), Expect = 4e-06
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 16/145 (11%)
Query: 435 NISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCS 494
N+ C + L L GC I + +A SC I L +N +TD +AL +CS
Sbjct: 25 NLGNGCHKLI-YLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCS 83
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFI-- 552
++ + P +SD + +AL+ C L + + +T++ + + + P L
Sbjct: 84 RITSLVFTGAPHISDCTFRALS-ACK-LRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMA 141
Query: 553 -CKGKPRESVPRLRIDDSGIESLGP 576
CKG I DS + SL P
Sbjct: 142 DCKG----------ITDSSLRSLSP 156
>Z97653-1|CAJ55832.1| 479|Homo sapiens F-box and leucine-rich
repeat protein 16 protein.
Length = 479
Score = 56.0 bits (129), Expect = 4e-07
Identities = 29/104 (27%), Positives = 53/104 (50%)
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
R G L L C I + + + S PN+ L+L+ C K+TD + + KL+
Sbjct: 291 RQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRS 350
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
++L CP ++D++L+ +A L + + C IT++G+ L+
Sbjct: 351 LDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLS 394
Score = 51.2 bits (117), Expect = 1e-05
Identities = 28/115 (24%), Positives = 53/115 (46%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+ LS+ C ++ D ++ ++Q PN+ +L+L R+ + L S
Sbjct: 244 ITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLS 303
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKGKPR 558
C +++ + + P LT +++S C +T+ GVE +A KL+S PR
Sbjct: 304 CWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPR 358
Score = 39.9 bits (89), Expect = 0.025
Identities = 25/109 (22%), Positives = 48/109 (44%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L +LSL+ A+ + L L C +IT+ + L ++L
Sbjct: 270 LAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSG 329
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFI 552
C V+D ++ +A+ L +++SWC IT+ +E +A +L+ +
Sbjct: 330 CSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELV 378
>BC036680-1|AAH36680.1| 479|Homo sapiens F-box and leucine-rich
repeat protein 16 protein.
Length = 479
Score = 56.0 bits (129), Expect = 4e-07
Identities = 29/104 (27%), Positives = 53/104 (50%)
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
R G L L C I + + + S PN+ L+L+ C K+TD + + KL+
Sbjct: 291 RQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRS 350
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
++L CP ++D++L+ +A L + + C IT++G+ L+
Sbjct: 351 LDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLS 394
Score = 51.2 bits (117), Expect = 1e-05
Identities = 28/115 (24%), Positives = 53/115 (46%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+ LS+ C ++ D ++ ++Q PN+ +L+L R+ + L S
Sbjct: 244 ITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLS 303
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKGKPR 558
C +++ + + P LT +++S C +T+ GVE +A KL+S PR
Sbjct: 304 CWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPR 358
Score = 39.9 bits (89), Expect = 0.025
Identities = 25/109 (22%), Positives = 48/109 (44%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L +LSL+ A+ + L L C +IT+ + L ++L
Sbjct: 270 LAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSG 329
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFI 552
C V+D ++ +A+ L +++SWC IT+ +E +A +L+ +
Sbjct: 330 CSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELV 378
>AE006464-13|AAK61245.1| 581|Homo sapiens possible G-protein
receptor protein.
Length = 581
Score = 56.0 bits (129), Expect = 4e-07
Identities = 29/104 (27%), Positives = 53/104 (50%)
Query: 439 RCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQK 498
R G L L C I + + + S PN+ L+L+ C K+TD + + KL+
Sbjct: 323 RQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRS 382
Query: 499 INLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALA 542
++L CP ++D++L+ +A L + + C IT++G+ L+
Sbjct: 383 LDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLS 426
Score = 51.2 bits (117), Expect = 1e-05
Identities = 28/115 (24%), Positives = 53/115 (46%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
+ LS+ C ++ D ++ ++Q PN+ +L+L R+ + L S
Sbjct: 276 ITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLS 335
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFICKGKPR 558
C +++ + + P LT +++S C +T+ GVE +A KL+S PR
Sbjct: 336 CWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPR 390
Score = 39.9 bits (89), Expect = 0.025
Identities = 25/109 (22%), Positives = 48/109 (44%)
Query: 444 LRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDS 503
L +LSL+ A+ + L L C +IT+ + L ++L
Sbjct: 302 LAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSG 361
Query: 504 CPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLKSFI 552
C V+D ++ +A+ L +++SWC IT+ +E +A +L+ +
Sbjct: 362 CSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELV 410
>BC008735-1|AAH08735.2| 627|Homo sapiens FBXL10 protein protein.
Length = 627
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/173 (27%), Positives = 88/173 (50%), Gaps = 13/173 (7%)
Query: 375 INRKLP--KELLLRILSYLDVVSLCRCA-QVSKLWNILALDG-SNWQRIDLFEFQRDVEG 430
INR LP ++L+L S++ V +LC + + + ++ ++G + Q DL D
Sbjct: 436 INR-LPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRP 494
Query: 431 PVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQ--- 487
++N S+ + +L L G + I D S++ + + P + L+L+ C +TDQ+
Sbjct: 495 GQMDNRSKLRN--IVELRLAGLD-ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 551
Query: 488 ALGRRC-SKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
A+G L +INL C V+D L + C + H+++ +C+ +T+ G E
Sbjct: 552 AVGTTTRDSLTEINLSDCNKVTDQCL-SFFKRCGNICHIDLRYCKQVTKEGCE 603
Score = 38.7 bits (86), Expect = 0.058
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 9/136 (6%)
Query: 381 KELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRC 440
+E+ + + SYL LC C +V + WN D W RIDL + + ++ I +R
Sbjct: 358 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRR- 415
Query: 441 GGFLRQLSL-RGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKI 499
+ +SL +I + L P + DL L+ C I C L+ +
Sbjct: 416 ----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIA--VSALCSSSCPLLRTL 469
Query: 500 NLDSCPSVSDISLKAL 515
++ + D ++ L
Sbjct: 470 DVQWVEGLKDAQMRDL 485
>AK027692-1|BAB55301.1| 653|Homo sapiens protein ( Homo sapiens
cDNA FLJ14786 fis, clone NT2RP4000737, moderately
similar to Mus musculus F-box protein FBL10 mRNA. ).
Length = 653
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/173 (27%), Positives = 88/173 (50%), Gaps = 13/173 (7%)
Query: 375 INRKLP--KELLLRILSYLDVVSLCRCA-QVSKLWNILALDG-SNWQRIDLFEFQRDVEG 430
INR LP ++L+L S++ V +LC + + + ++ ++G + Q DL D
Sbjct: 462 INR-LPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRP 520
Query: 431 PVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQ--- 487
++N S+ + +L L G + I D S++ + + P + L+L+ C +TDQ+
Sbjct: 521 GQMDNRSKLRN--IVELRLAGLD-ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 577
Query: 488 ALGRRC-SKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
A+G L +INL C V+D L + C + H+++ +C+ +T+ G E
Sbjct: 578 AVGTTTRDSLTEINLSDCNKVTDQCL-SFFKRCGNICHIDLRYCKQVTKEGCE 629
Score = 38.7 bits (86), Expect = 0.058
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 9/136 (6%)
Query: 381 KELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRC 440
+E+ + + SYL LC C +V + WN D W RIDL + + ++ I +R
Sbjct: 384 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRR- 441
Query: 441 GGFLRQLSL-RGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKI 499
+ +SL +I + L P + DL L+ C I C L+ +
Sbjct: 442 ----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIA--VSALCSSSCPLLRTL 495
Query: 500 NLDSCPSVSDISLKAL 515
++ + D ++ L
Sbjct: 496 DVQWVEGLKDAQMRDL 511
>AK027440-1|BAB55112.1| 704|Homo sapiens protein ( Homo sapiens
cDNA FLJ14534 fis, clone NT2RM2000599, weakly similar to
Homo sapiens F-box protein Lilina (LILINA) mRNA. ).
Length = 704
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/173 (27%), Positives = 88/173 (50%), Gaps = 13/173 (7%)
Query: 375 INRKLP--KELLLRILSYLDVVSLCRCA-QVSKLWNILALDG-SNWQRIDLFEFQRDVEG 430
INR LP ++L+L S++ V +LC + + + ++ ++G + Q DL D
Sbjct: 513 INR-LPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRP 571
Query: 431 PVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQ--- 487
++N S+ + +L L G + I D S++ + + P + L+L+ C +TDQ+
Sbjct: 572 GQMDNRSKLRN--IVELRLAGLD-ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 628
Query: 488 ALGRRC-SKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
A+G L +INL C V+D L + C + H+++ +C+ +T+ G E
Sbjct: 629 AVGTTTRDSLTEINLSDCNKVTDQCL-SFFKRCGNICHIDLRYCKQVTKEGCE 680
Score = 38.7 bits (86), Expect = 0.058
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 9/136 (6%)
Query: 381 KELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRC 440
+E+ + + SYL LC C +V + WN D W RIDL + + ++ I +R
Sbjct: 435 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRR- 492
Query: 441 GGFLRQLSL-RGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKI 499
+ +SL +I + L P + DL L+ C I C L+ +
Sbjct: 493 ----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIA--VSALCSSSCPLLRTL 546
Query: 500 NLDSCPSVSDISLKAL 515
++ + D ++ L
Sbjct: 547 DVQWVEGLKDAQMRDL 562
>AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.
Length = 1336
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/173 (27%), Positives = 88/173 (50%), Gaps = 13/173 (7%)
Query: 375 INRKLP--KELLLRILSYLDVVSLCRCA-QVSKLWNILALDG-SNWQRIDLFEFQRDVEG 430
INR LP ++L+L S++ V +LC + + + ++ ++G + Q DL D
Sbjct: 1145 INR-LPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRP 1203
Query: 431 PVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQ--- 487
++N S+ + +L L G + I D S++ + + P + L+L+ C +TDQ+
Sbjct: 1204 GQMDNRSKLRN--IVELRLAGLD-ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 1260
Query: 488 ALGRRC-SKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
A+G L +INL C V+D L + C + H+++ +C+ +T+ G E
Sbjct: 1261 AVGTTTRDSLTEINLSDCNKVTDQCL-SFFKRCGNICHIDLRYCKQVTKEGCE 1312
Score = 38.7 bits (86), Expect = 0.058
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 9/136 (6%)
Query: 381 KELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRC 440
+E+ + + SYL LC C +V + WN D W RIDL + + ++ I +R
Sbjct: 1067 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRR- 1124
Query: 441 GGFLRQLSL-RGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKI 499
+ +SL +I + L P + DL L+ C I C L+ +
Sbjct: 1125 ----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIA--VSALCSSSCPLLRTL 1178
Query: 500 NLDSCPSVSDISLKAL 515
++ + D ++ L
Sbjct: 1179 DVQWVEGLKDAQMRDL 1194
>AK074718-1|BAC11159.1| 458|Homo sapiens protein ( Homo sapiens
cDNA FLJ90237 fis, clone NT2RM2000622. ).
Length = 458
Score = 49.2 bits (112), Expect = 4e-05
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 13/173 (7%)
Query: 375 INRKLP--KELLLRILSYLDVVSLCRCA-QVSKLWNILALDG-SNWQRIDLFEFQRDVEG 430
INR LP ++L+L S++ V +LC + + + ++ ++G + Q DL D
Sbjct: 267 INR-LPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRP 325
Query: 431 PVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQ--- 487
++N S+ + +L L G + I D S++ + + P + L+L+ C +TDQ+
Sbjct: 326 GQMDNRSKLRN--IVELRLAGLD-IRDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 382
Query: 488 ALGRRC-SKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVE 539
A+G L +INL C V+D L + C H+++ +C+ +T+ G E
Sbjct: 383 AVGTTTRDSLTEINLSDCNKVTDQCL-SFFKRCGNTCHIDLRYCKQVTKEGCE 434
Score = 38.7 bits (86), Expect = 0.058
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 9/136 (6%)
Query: 381 KELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRC 440
+E+ + + SYL LC C +V + WN D W RIDL + + ++ I +R
Sbjct: 189 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRR- 246
Query: 441 GGFLRQLSL-RGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKI 499
+ +SL +I + L P + DL L+ C I C L+ +
Sbjct: 247 ----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIA--VSALCSSSCPLLRTL 300
Query: 500 NLDSCPSVSDISLKAL 515
++ + D ++ L
Sbjct: 301 DVQWVEGLKDAQMRDL 316
>BX537957-1|CAD97924.1| 697|Homo sapiens hypothetical protein
protein.
Length = 697
Score = 46.8 bits (106), Expect = 2e-04
Identities = 20/41 (48%), Positives = 27/41 (65%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
LP E++L I SYL+ LCRC+QVS W+ L GS W+ +
Sbjct: 214 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 254
Score = 41.9 bits (94), Expect = 0.006
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 499 INLDSCPSVSDISLKALA--DGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
++L C ++D L+ L G P L H+N+S C +IT +G++ L CP L
Sbjct: 609 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 660
Score = 41.1 bits (92), Expect = 0.011
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 3/115 (2%)
Query: 437 SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCS 494
S C R RG + I GS K+ ++ + L+L+ C +ITD + L G
Sbjct: 573 SAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLP 632
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L+ +NL C +++ L+ L CP L +C +I + A GC L+
Sbjct: 633 YLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 686
Score = 40.3 bits (90), Expect = 0.019
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 419 IDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKC 478
I + + ++ + +I N+ G ++ L L ++ ++ + + CPN+E L+L +
Sbjct: 313 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ- 371
Query: 479 KKITDQTCQA---LGRRCSKLQKINLDSCPSVSDISLKALADGCPLLT 523
I+D + LG C L+ ++L C ++D++L+ ++ +LT
Sbjct: 372 TDISDSAFDSWSWLG-CCQSLRHLDLSGCEKITDVALEKISRALGILT 418
Score = 39.1 bits (87), Expect = 0.044
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 3/88 (3%)
Query: 434 ENISQRCGGFLRQLSLRGCESIGDGSMK--TLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E Q G L LSL GC I D ++ TL P +E LNL+ C IT Q L
Sbjct: 596 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 655
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGC 519
C L C +++ A GC
Sbjct: 656 ACPSLNDEYFYYCDNINGPHADT-ASGC 682
>BC130445-1|AAI30446.1| 843|Homo sapiens F-box protein 11 protein.
Length = 843
Score = 46.8 bits (106), Expect = 2e-04
Identities = 25/62 (40%), Positives = 38/62 (61%), Gaps = 2/62 (3%)
Query: 372 ENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI--DLFEFQRDVE 429
E ++ KLP E++L+I SYL LCR A V K ++ LA D W+R+ ++FE+ R +
Sbjct: 68 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMM 127
Query: 430 GP 431
P
Sbjct: 128 HP 129
>BC043258-1|AAH43258.2| 915|Homo sapiens FBXO11 protein protein.
Length = 915
Score = 46.8 bits (106), Expect = 2e-04
Identities = 25/62 (40%), Positives = 38/62 (61%), Gaps = 2/62 (3%)
Query: 372 ENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI--DLFEFQRDVE 429
E ++ KLP E++L+I SYL LCR A V K ++ LA D W+R+ ++FE+ R +
Sbjct: 140 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMM 199
Query: 430 GP 431
P
Sbjct: 200 HP 201
>AY827075-1|AAV87312.1| 927|Homo sapiens F-box protein 11 protein.
Length = 927
Score = 46.8 bits (106), Expect = 2e-04
Identities = 25/62 (40%), Positives = 38/62 (61%), Gaps = 2/62 (3%)
Query: 372 ENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI--DLFEFQRDVE 429
E ++ KLP E++L+I SYL LCR A V K ++ LA D W+R+ ++FE+ R +
Sbjct: 152 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMM 211
Query: 430 GP 431
P
Sbjct: 212 HP 213
>AK223592-1|BAD97312.1| 843|Homo sapiens F-box only protein 11
isoform 1 variant protein.
Length = 843
Score = 46.8 bits (106), Expect = 2e-04
Identities = 25/62 (40%), Positives = 38/62 (61%), Gaps = 2/62 (3%)
Query: 372 ENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI--DLFEFQRDVE 429
E ++ KLP E++L+I SYL LCR A V K ++ LA D W+R+ ++FE+ R +
Sbjct: 68 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMM 127
Query: 430 GP 431
P
Sbjct: 128 HP 129
>AK000153-1|BAA90978.1| 636|Homo sapiens protein ( Homo sapiens
cDNA FLJ20146 fis, clone COL07877. ).
Length = 636
Score = 46.8 bits (106), Expect = 2e-04
Identities = 20/41 (48%), Positives = 27/41 (65%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
LP E++L I SYL+ LCRC+QVS W+ L GS W+ +
Sbjct: 153 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 193
Score = 41.9 bits (94), Expect = 0.006
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 499 INLDSCPSVSDISLKALA--DGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
++L C ++D L+ L G P L H+N+S C +IT +G++ L CP L
Sbjct: 548 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 599
Score = 41.1 bits (92), Expect = 0.011
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 3/115 (2%)
Query: 437 SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCS 494
S C R RG + I GS K+ ++ + L+L+ C +ITD + L G
Sbjct: 512 SAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLP 571
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L+ +NL C +++ L+ L CP L +C +I + A GC L+
Sbjct: 572 YLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 625
Score = 40.3 bits (90), Expect = 0.019
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 419 IDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKC 478
I + + ++ + +I N+ G ++ L L ++ ++ + + CPN+E L+L +
Sbjct: 252 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ- 310
Query: 479 KKITDQTCQA---LGRRCSKLQKINLDSCPSVSDISLKALADGCPLLT 523
I+D + LG C L+ ++L C ++D++L+ ++ +LT
Sbjct: 311 TDISDSAFDSWSWLG-CCQSLRHLDLSGCEKITDVALEKISRALGILT 357
Score = 39.1 bits (87), Expect = 0.044
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 3/88 (3%)
Query: 434 ENISQRCGGFLRQLSLRGCESIGDGSMK--TLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E Q G L LSL GC I D ++ TL P +E LNL+ C IT Q L
Sbjct: 535 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 594
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGC 519
C L C +++ A GC
Sbjct: 595 ACPSLNDEYFYYCDNINGPHADT-ASGC 621
>AF199420-1|AAF09249.1| 690|Homo sapiens F-box protein FBL4
protein.
Length = 690
Score = 46.8 bits (106), Expect = 2e-04
Identities = 20/41 (48%), Positives = 27/41 (65%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
LP E++L I SYL+ LCRC+QVS W+ L GS W+ +
Sbjct: 207 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 247
Score = 41.9 bits (94), Expect = 0.006
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 499 INLDSCPSVSDISLKALA--DGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
++L C ++D L+ L G P L H+N+S C +IT +G++ L CP L
Sbjct: 602 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 653
Score = 41.1 bits (92), Expect = 0.011
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 3/115 (2%)
Query: 437 SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCS 494
S C R RG + I GS K+ ++ + L+L+ C +ITD + L G
Sbjct: 566 SAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLP 625
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L+ +NL C +++ L+ L CP L +C +I + A GC L+
Sbjct: 626 YLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 679
Score = 40.3 bits (90), Expect = 0.019
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 419 IDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKC 478
I + + ++ + +I N+ G ++ L L ++ ++ + + CPN+E L+L +
Sbjct: 306 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ- 364
Query: 479 KKITDQTCQA---LGRRCSKLQKINLDSCPSVSDISLKALADGCPLLT 523
I+D + LG C L+ ++L C ++D++L+ ++ +LT
Sbjct: 365 TDISDSAFDSWSWLG-CCQSLRHLDLSGCEKITDVALEKISRALGILT 411
Score = 39.1 bits (87), Expect = 0.044
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 3/88 (3%)
Query: 434 ENISQRCGGFLRQLSLRGCESIGDGSMK--TLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E Q G L LSL GC I D ++ TL P +E LNL+ C IT Q L
Sbjct: 589 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 648
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGC 519
C L C +++ A GC
Sbjct: 649 ACPSLNDEYFYYCDNINGPHADT-ASGC 675
>AF176700-1|AAF03700.1| 694|Homo sapiens F-box protein FBL5
protein.
Length = 694
Score = 46.8 bits (106), Expect = 2e-04
Identities = 20/41 (48%), Positives = 27/41 (65%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
LP E++L I SYL+ LCRC+QVS W+ L GS W+ +
Sbjct: 211 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 251
Score = 41.9 bits (94), Expect = 0.006
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 499 INLDSCPSVSDISLKALA--DGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
++L C ++D L+ L G P L H+N+S C +IT +G++ L CP L
Sbjct: 606 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 657
Score = 41.1 bits (92), Expect = 0.011
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 3/115 (2%)
Query: 437 SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCS 494
S C R RG + I GS K+ ++ + L+L+ C +ITD + L G
Sbjct: 570 SAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLP 629
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L+ +NL C +++ L+ L CP L +C +I + A GC L+
Sbjct: 630 YLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 683
Score = 40.3 bits (90), Expect = 0.019
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 419 IDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKC 478
I + + ++ + +I N+ G ++ L L ++ ++ + + CPN+E L+L +
Sbjct: 310 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ- 368
Query: 479 KKITDQTCQA---LGRRCSKLQKINLDSCPSVSDISLKALADGCPLLT 523
I+D + LG C L+ ++L C ++D++L+ ++ +LT
Sbjct: 369 TDISDSAFDSWSWLG-CCQSLRHLDLSGCEKITDVALEKISRALGILT 415
Score = 39.1 bits (87), Expect = 0.044
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 3/88 (3%)
Query: 434 ENISQRCGGFLRQLSLRGCESIGDGSMK--TLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E Q G L LSL GC I D ++ TL P +E LNL+ C IT Q L
Sbjct: 593 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 652
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGC 519
C L C +++ A GC
Sbjct: 653 ACPSLNDEYFYYCDNINGPHADT-ASGC 679
>AF174599-1|AAF04520.1| 197|Homo sapiens F-box protein Fbx11
protein.
Length = 197
Score = 46.8 bits (106), Expect = 2e-04
Identities = 24/57 (42%), Positives = 37/57 (64%), Gaps = 2/57 (3%)
Query: 372 ENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI--DLFEFQR 426
E ++ KLP E++L+I SYL LCR A V K ++ LA D + W+R+ ++FE+ R
Sbjct: 137 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPNLWKRLYMEVFEYTR 193
>AF174591-1|AAF04512.1| 535|Homo sapiens F-box protein Fbl5
protein.
Length = 535
Score = 46.8 bits (106), Expect = 2e-04
Identities = 20/41 (48%), Positives = 27/41 (65%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
LP E++L I SYL+ LCRC+QVS W+ L GS W+ +
Sbjct: 52 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 92
Score = 41.9 bits (94), Expect = 0.006
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 499 INLDSCPSVSDISLKALA--DGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
++L C ++D L+ L G P L H+N+S C +IT +G++ L CP L
Sbjct: 447 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 498
Score = 41.1 bits (92), Expect = 0.011
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 3/115 (2%)
Query: 437 SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCS 494
S C R RG + I GS K+ ++ + L+L+ C +ITD + L G
Sbjct: 411 SAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLP 470
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L+ +NL C +++ L+ L CP L +C +I + A GC L+
Sbjct: 471 YLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 524
Score = 40.3 bits (90), Expect = 0.019
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 419 IDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKC 478
I + + ++ + +I N+ G ++ L L ++ ++ + + CPN+E L+L +
Sbjct: 151 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ- 209
Query: 479 KKITDQTCQA---LGRRCSKLQKINLDSCPSVSDISLKALADGCPLLT 523
I+D + LG C L+ ++L C ++D++L+ ++ +LT
Sbjct: 210 TDISDSAFDSWSWLG-CCQSLRHLDLSGCEKITDVALEKISRALGILT 256
Score = 39.1 bits (87), Expect = 0.044
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 3/88 (3%)
Query: 434 ENISQRCGGFLRQLSLRGCESIGDGSMK--TLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E Q G L LSL GC I D ++ TL P +E LNL+ C IT Q L
Sbjct: 434 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 493
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGC 519
C L C +++ A GC
Sbjct: 494 ACPSLNDEYFYYCDNINGPHADT-ASGC 520
>AF157323-1|AAF67489.1| 674|Homo sapiens p45SKP2-like protein
protein.
Length = 674
Score = 46.8 bits (106), Expect = 2e-04
Identities = 20/41 (48%), Positives = 27/41 (65%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
LP E++L I SYL+ LCRC+QVS W+ L GS W+ +
Sbjct: 191 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 231
Score = 41.9 bits (94), Expect = 0.006
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 499 INLDSCPSVSDISLKALA--DGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
++L C ++D L+ L G P L H+N+S C +IT +G++ L CP L
Sbjct: 586 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 637
Score = 41.1 bits (92), Expect = 0.011
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 3/115 (2%)
Query: 437 SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCS 494
S C R RG + I GS K+ ++ + L+L+ C +ITD + L G
Sbjct: 550 SAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLP 609
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L+ +NL C +++ L+ L CP L +C +I + A GC L+
Sbjct: 610 YLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 663
Score = 40.3 bits (90), Expect = 0.019
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 419 IDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKC 478
I + + ++ + +I N+ G ++ L L ++ ++ + + CPN+E L+L +
Sbjct: 290 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ- 348
Query: 479 KKITDQTCQA---LGRRCSKLQKINLDSCPSVSDISLKALADGCPLLT 523
I+D + LG C L+ ++L C ++D++L+ ++ +LT
Sbjct: 349 TDISDSAFDSWSWLG-CCQSLRHLDLSGCEKITDVALEKISRALGILT 395
Score = 39.1 bits (87), Expect = 0.044
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 3/88 (3%)
Query: 434 ENISQRCGGFLRQLSLRGCESIGDGSMK--TLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E Q G L LSL GC I D ++ TL P +E LNL+ C IT Q L
Sbjct: 573 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 632
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGC 519
C L C +++ A GC
Sbjct: 633 ACPSLNDEYFYYCDNINGPHADT-ASGC 659
>AF142481-1|AAF66616.1| 691|Homo sapiens F-box protein FLR1
protein.
Length = 691
Score = 46.8 bits (106), Expect = 2e-04
Identities = 20/41 (48%), Positives = 27/41 (65%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
LP E++L I SYL+ LCRC+QVS W+ L GS W+ +
Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 248
Score = 41.9 bits (94), Expect = 0.006
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 499 INLDSCPSVSDISLKALA--DGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
++L C ++D L+ L G P L H+N+S C +IT +G++ L CP L
Sbjct: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 654
Score = 41.1 bits (92), Expect = 0.011
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 3/115 (2%)
Query: 437 SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCS 494
S C R RG + I GS K+ ++ + L+L+ C +ITD + L G
Sbjct: 567 SAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLP 626
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L+ +NL C +++ L+ L CP L +C +I + A GC L+
Sbjct: 627 YLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 680
Score = 40.3 bits (90), Expect = 0.019
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 419 IDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKC 478
I + + ++ + +I N+ G ++ L L ++ ++ + + CPN+E L+L +
Sbjct: 307 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ- 365
Query: 479 KKITDQTCQA---LGRRCSKLQKINLDSCPSVSDISLKALADGCPLLT 523
I+D + LG C L+ ++L C ++D++L+ ++ +LT
Sbjct: 366 TDISDSAFDSWSWLG-CCQSLRHLDLSGCEKITDVALEKISRALGILT 412
Score = 39.1 bits (87), Expect = 0.044
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 3/88 (3%)
Query: 434 ENISQRCGGFLRQLSLRGCESIGDGSMK--TLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E Q G L LSL GC I D ++ TL P +E LNL+ C IT Q L
Sbjct: 590 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 649
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGC 519
C L C +++ A GC
Sbjct: 650 ACPSLNDEYFYYCDNINGPHADT-ASGC 676
>AC114744-1|AAY40929.1| 616|Homo sapiens unknown protein.
Length = 616
Score = 46.8 bits (106), Expect = 2e-04
Identities = 20/41 (48%), Positives = 27/41 (65%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
LP E++L I SYL+ LCRC+QVS W+ L GS W+ +
Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHL 248
Score = 40.3 bits (90), Expect = 0.019
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 419 IDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKC 478
I + + ++ + +I N+ G ++ L L ++ ++ + + CPN+E L+L +
Sbjct: 307 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ- 365
Query: 479 KKITDQTCQA---LGRRCSKLQKINLDSCPSVSDISLKALADGCPLLT 523
I+D + LG C L+ ++L C ++D++L+ ++ +LT
Sbjct: 366 TDISDSAFDSWSWLG-CCQSLRHLDLSGCEKITDVALEKISRALGILT 412
>AC079807-1|AAY24083.1| 584|Homo sapiens unknown protein.
Length = 584
Score = 46.8 bits (106), Expect = 2e-04
Identities = 25/62 (40%), Positives = 38/62 (61%), Gaps = 2/62 (3%)
Query: 372 ENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI--DLFEFQRDVE 429
E ++ KLP E++L+I SYL LCR A V K ++ LA D W+R+ ++FE+ R +
Sbjct: 68 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMM 127
Query: 430 GP 431
P
Sbjct: 128 HP 129
>BC037296-1|AAH37296.1| 598|Homo sapiens F-box and WD repeat domain
containing 8 protein.
Length = 598
Score = 46.4 bits (105), Expect = 3e-04
Identities = 21/42 (50%), Positives = 26/42 (61%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
+LP EL + I YLD L RCAQVSK W ++A D W R+
Sbjct: 118 QLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRL 159
>AF176707-1|AAF03129.1| 551|Homo sapiens F-box protein FBX29
protein.
Length = 551
Score = 46.4 bits (105), Expect = 3e-04
Identities = 21/42 (50%), Positives = 26/42 (61%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
+LP EL + I YLD L RCAQVSK W ++A D W R+
Sbjct: 72 QLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRL 113
>BC033066-1|AAH33066.1| 539|Homo sapiens F-box and leucine-rich
repeat protein 6 protein.
Length = 539
Score = 44.8 bits (101), Expect = 9e-04
Identities = 39/140 (27%), Positives = 64/140 (45%), Gaps = 6/140 (4%)
Query: 414 SNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDL 473
S QR+ L ++ V PV++ + + C L L L GC + ++ LA++C + L
Sbjct: 194 SQLQRLTLIHWKSQVH-PVLKLVGECCPR-LTFLKLSGCHGVTADALVMLAKACCQLHSL 251
Query: 474 NLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSW---C 530
+L + L S+++K+ L + I L CP L + VS
Sbjct: 252 DLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINR 311
Query: 531 QSI-TESGVEALARGCPKLK 549
SI + VEAL +GCP+L+
Sbjct: 312 NSIPLQLPVEALQKGCPQLQ 331
Score = 38.3 bits (85), Expect = 0.076
Identities = 22/72 (30%), Positives = 35/72 (48%)
Query: 479 KKITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGV 538
KK+ + R S+LQ++ L S LK + + CP LT + +S C +T +
Sbjct: 179 KKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADAL 238
Query: 539 EALARGCPKLKS 550
LA+ C +L S
Sbjct: 239 VMLAKACCQLHS 250
Score = 33.5 bits (73), Expect = 2.2
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 452 CESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDIS 511
C + + + L PN+ L+L C +IT Q L C +L++++L SD
Sbjct: 368 CNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDL--PCRELEQLHL-GLYGTSD-R 423
Query: 512 LKALADGCPLLTHVNVSWCQSITE 535
L +G P LT WC ++ E
Sbjct: 424 LTLAKEGSPFLTQ---KWCHTLRE 444
>BC001586-1|AAH01586.1| 326|Homo sapiens F-box and leucine-rich
repeat protein 12 protein.
Length = 326
Score = 44.8 bits (101), Expect = 9e-04
Identities = 51/206 (24%), Positives = 88/206 (42%), Gaps = 19/206 (9%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRID--LFEFQRDVEGPVIEN 435
+LP +LL I SYL V R ++V W L D W+ +D L+ + V ++
Sbjct: 6 ELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLLRR 65
Query: 436 I------SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
S R GG+L S + ++ L Q CPN++ L C + D + +
Sbjct: 66 YMASRLHSLRMGGYL--FSGSQAPQLSPALLRALGQKCPNLKRL----CLHVADLSMVPI 119
Query: 490 GRRCSKLQKINLDSCP-SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
S L+ + L SC S++ + + PLL + + + + ++ L R L
Sbjct: 120 TSLPSTLRTLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTR-FRAL 178
Query: 549 KSFICKGKPRESVPRLRIDDSGIESL 574
+S + G R + L D+G++ L
Sbjct: 179 RSLVLGGTYRVTETGL---DAGLQEL 201
>AK000195-1|BAA91002.1| 326|Homo sapiens protein ( Homo sapiens
cDNA FLJ20188 fis, clone COLF0561. ).
Length = 326
Score = 44.8 bits (101), Expect = 9e-04
Identities = 51/206 (24%), Positives = 88/206 (42%), Gaps = 19/206 (9%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRID--LFEFQRDVEGPVIEN 435
+LP +LL I SYL V R ++V W L D W+ +D L+ + V ++
Sbjct: 6 ELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLLRR 65
Query: 436 I------SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL 489
S R GG+L S + ++ L Q CPN++ L C + D + +
Sbjct: 66 YMASRLHSLRMGGYL--FSGSQAPQLSPALLRALGQKCPNLKRL----CLHVADLSMVPI 119
Query: 490 GRRCSKLQKINLDSCP-SVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
S L+ + L SC S++ + + PLL + + + + ++ L R L
Sbjct: 120 TSLPSTLRTLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTR-FRAL 178
Query: 549 KSFICKGKPRESVPRLRIDDSGIESL 574
+S + G R + L D+G++ L
Sbjct: 179 RSLVLGGTYRVTETGL---DAGLQEL 201
>AF174592-1|AAF04513.1| 283|Homo sapiens F-box protein Fbl6
protein.
Length = 283
Score = 44.8 bits (101), Expect = 9e-04
Identities = 39/140 (27%), Positives = 64/140 (45%), Gaps = 6/140 (4%)
Query: 414 SNWQRIDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDL 473
S QR+ L ++ V PV++ + + C L L L GC + ++ LA++C + L
Sbjct: 105 SQLQRLTLIHWKSQVH-PVLKLVGECCPR-LTFLKLSGCHGVTADALVMLAKACCQLHSL 162
Query: 474 NLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSW---C 530
+L + L S+++K+ L + I L CP L + VS
Sbjct: 163 DLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINR 222
Query: 531 QSI-TESGVEALARGCPKLK 549
SI + VEAL +GCP+L+
Sbjct: 223 NSIPLQLPVEALQKGCPQLQ 242
Score = 38.3 bits (85), Expect = 0.076
Identities = 22/72 (30%), Positives = 35/72 (48%)
Query: 479 KKITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGV 538
KK+ + R S+LQ++ L S LK + + CP LT + +S C +T +
Sbjct: 90 KKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADAL 149
Query: 539 EALARGCPKLKS 550
LA+ C +L S
Sbjct: 150 VMLAKACCQLHS 161
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 44.8 bits (101), Expect = 9e-04
Identities = 18/42 (42%), Positives = 27/42 (64%)
Query: 176 VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 217
VD TW +E + G+ K IG+SNFN++QLE +L + +K
Sbjct: 19 VDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 60
>BC059173-1|AAH59173.1| 524|Homo sapiens F-box and leucine-rich
repeat protein 19 protein.
Length = 524
Score = 43.6 bits (98), Expect = 0.002
Identities = 29/81 (35%), Positives = 42/81 (51%), Gaps = 5/81 (6%)
Query: 444 LRQLSLRGCESIGDGSMKTL-AQSCP---NIEDLNLNKCKKITDQTCQALGRRCSKLQKI 499
L L L C +GD S+ L A + P + LNL C ++TD C L RRC +L+++
Sbjct: 429 LSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHRLTDH-CLPLFRRCPRLRRL 487
Query: 500 NLDSCPSVSDISLKALADGCP 520
+L SC +S + LA P
Sbjct: 488 DLRSCRQLSPEACARLAAAGP 508
Score = 36.7 bits (81), Expect = 0.23
Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQ 438
LP+ LR+ +L LC C +V + W+ D W R+DL ++ + P++ + +
Sbjct: 254 LPRAAWLRVFQHLGPRELCICMRVCRTWSRWCYDKRLWPRMDLSR-RKSLTPPMLSGVVR 312
Query: 439 R 439
R
Sbjct: 313 R 313
>BC030656-1|AAH30656.1| 691|Homo sapiens F-box and leucine-rich
repeat protein 5 protein.
Length = 691
Score = 43.6 bits (98), Expect = 0.002
Identities = 19/41 (46%), Positives = 26/41 (63%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
LP E++L I SYL+ LCRC+QVS W+ L S W+ +
Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTRSLWKHL 248
Score = 41.9 bits (94), Expect = 0.006
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%)
Query: 499 INLDSCPSVSDISLKALA--DGCPLLTHVNVSWCQSITESGVEALARGCPKL 548
++L C ++D L+ L G P L H+N+S C +IT +G++ L CP L
Sbjct: 603 LSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 654
Score = 41.1 bits (92), Expect = 0.011
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 3/115 (2%)
Query: 437 SQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQAL--GRRCS 494
S C R RG + I GS K+ ++ + L+L+ C +ITD + L G
Sbjct: 567 SAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLP 626
Query: 495 KLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEALARGCPKLK 549
L+ +NL C +++ L+ L CP L +C +I + A GC L+
Sbjct: 627 YLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 680
Score = 40.3 bits (90), Expect = 0.019
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 419 IDLFEFQRDVEGPVIENISQRCGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKC 478
I + + ++ + +I N+ G ++ L L ++ ++ + + CPN+E L+L +
Sbjct: 307 ISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ- 365
Query: 479 KKITDQTCQA---LGRRCSKLQKINLDSCPSVSDISLKALADGCPLLT 523
I+D + LG C L+ ++L C ++D++L+ ++ +LT
Sbjct: 366 TDISDSAFDSWSWLG-CCQSLRHLDLSGCEKITDVALEKISRALGILT 412
Score = 39.1 bits (87), Expect = 0.044
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 3/88 (3%)
Query: 434 ENISQRCGGFLRQLSLRGCESIGDGSMK--TLAQSCPNIEDLNLNKCKKITDQTCQALGR 491
E Q G L LSL GC I D ++ TL P +E LNL+ C IT Q L
Sbjct: 590 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 649
Query: 492 RCSKLQKINLDSCPSVSDISLKALADGC 519
C L C +++ A GC
Sbjct: 650 ACPSLNDEYFYYCDNINGPHADT-ASGC 676
>U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit
protein.
Length = 367
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 66 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 121
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 122 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 173
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 174 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 233
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 234 HKIGVGAMTWSP 245
>CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 52 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 107
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 108 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 159
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 160 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 219
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 220 HKIGVGAMTWSP 231
>BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 66 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 121
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 122 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 173
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 174 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 233
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 234 HKIGVGAMTWSP 245
>BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 66 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 121
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 122 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 173
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 174 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 233
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 234 HKIGVGAMTWSP 245
>BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein.
Length = 395
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 66 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 121
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 122 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 173
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 174 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 233
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 234 HKIGVGAMTWSP 245
>AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 253
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 66 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 121
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 122 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 173
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 174 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 233
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 234 HKIGVGAMTWSP 245
>AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 254
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 52 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 107
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 108 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 159
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 160 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 219
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 220 HKIGVGAMTWSP 231
>AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 66 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 121
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 122 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 173
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 174 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 233
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 234 HKIGVGAMTWSP 245
>AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 353
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 52 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 107
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 108 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 159
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 160 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 219
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 220 HKIGVGAMTWSP 231
>AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta 2
subunit protein.
Length = 353
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 52 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 107
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 108 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 159
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 160 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 219
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 220 HKIGVGAMTWSP 231
>AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta 2
subunit protein.
Length = 367
Score = 40.3 bits (90), Expect = 0.019
Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 66 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 121
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++L L+Y+D+ + P + ET R +
Sbjct: 122 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--------DPNTPMEETVRAM 173
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 174 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELF 233
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 234 HKIGVGAMTWSP 245
>BC102028-1|AAI02029.1| 280|Homo sapiens FBXO16 protein protein.
Length = 280
Score = 39.9 bits (89), Expect = 0.025
Identities = 20/33 (60%), Positives = 22/33 (66%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILA 410
KLP+ L L I S+LD SLCRCAQV W LA
Sbjct: 79 KLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLA 111
>BC102027-1|AAI02028.1| 280|Homo sapiens FBXO16 protein protein.
Length = 280
Score = 39.9 bits (89), Expect = 0.025
Identities = 20/33 (60%), Positives = 22/33 (66%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILA 410
KLP+ L L I S+LD SLCRCAQV W LA
Sbjct: 79 KLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLA 111
>BC102026-1|AAI02027.1| 292|Homo sapiens F-box protein 16 protein.
Length = 292
Score = 39.9 bits (89), Expect = 0.025
Identities = 20/33 (60%), Positives = 22/33 (66%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILA 410
KLP+ L L I S+LD SLCRCAQV W LA
Sbjct: 91 KLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLA 123
>BC074986-1|AAH74986.1| 292|Homo sapiens F-box protein 16 protein.
Length = 292
Score = 39.9 bits (89), Expect = 0.025
Identities = 20/33 (60%), Positives = 22/33 (66%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILA 410
KLP+ L L I S+LD SLCRCAQV W LA
Sbjct: 91 KLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLA 123
>AF453435-1|AAN76812.1| 292|Homo sapiens F-box protein 16 protein.
Length = 292
Score = 39.9 bits (89), Expect = 0.025
Identities = 20/33 (60%), Positives = 22/33 (66%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILA 410
KLP+ L L I S+LD SLCRCAQV W LA
Sbjct: 91 KLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLA 123
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 39.9 bits (89), Expect = 0.025
Identities = 18/38 (47%), Positives = 24/38 (63%)
Query: 130 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 167
+W T R V + + SLKKL L Y+DLYL H+P+ L
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 38
>BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 284 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 322
>BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 284 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 322
>BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein.
Length = 621
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 198 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 236
>AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4
protein.
Length = 707
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 284 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 322
>AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7
protein.
Length = 627
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 204 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 242
>AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10
protein.
Length = 589
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 166 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 204
>AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 627
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 204 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 242
>AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ11071 fis, clone PLACE1004937, moderately
similar to SEL-10 PROTEIN. ).
Length = 553
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 130 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 168
>AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form
protein.
Length = 627
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 204 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 242
>AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form
protein.
Length = 707
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 284 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 322
>AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30
protein.
Length = 561
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 138 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 176
>AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 624
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
LPKEL L +LS+L+ L + AQ + W ILA D W+
Sbjct: 201 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 239
>DQ904332-1|ABI98402.1| 155|Homo sapiens F-box only protein 48
protein.
Length = 155
Score = 39.1 bits (87), Expect = 0.044
Identities = 16/39 (41%), Positives = 23/39 (58%)
Query: 369 NEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWN 407
NE +N+ LP E+ +I S LD+ SLCR + + WN
Sbjct: 28 NESQNNFFELLPAEITFKIFSQLDIRSLCRASLTCRSWN 66
>BC089423-1|AAH89423.1| 155|Homo sapiens hypothetical protein
LOC554251 protein.
Length = 155
Score = 39.1 bits (87), Expect = 0.044
Identities = 16/39 (41%), Positives = 23/39 (58%)
Query: 369 NEDENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWN 407
NE +N+ LP E+ +I S LD+ SLCR + + WN
Sbjct: 28 NESQNNFFELLPAEITFKIFSQLDIRSLCRASLTCRSWN 66
>AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ16180 fis, clone BRHIP3000240, highly similar
to Homo sapiens potassium channel beta 2 subunit
(HKvbeta2.2) mRNA. ).
Length = 415
Score = 39.1 bits (87), Expect = 0.044
Identities = 50/199 (25%), Positives = 86/199 (43%), Gaps = 28/199 (14%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 99 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 154
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWP---IGLNAD--YSHSDVDFM- 179
T+ R + + + SL++L L+Y+D+ + P + D S F+
Sbjct: 155 GGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEGDPFSSSKSRTFII 214
Query: 180 -ETWRGLEDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQ 231
ET R + G+ G S ++ ++ V ++ + P Q E H+ + V+
Sbjct: 215 EETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVE 274
Query: 232 KEMVEFCQSEGVVVMGYSP 250
++ E GV M +SP
Sbjct: 275 VQLPELFHKIGVGAMTWSP 293
>AF176706-1|AAF17611.1| 192|Homo sapiens F-box protein FBX11
protein.
Length = 192
Score = 39.1 bits (87), Expect = 0.044
Identities = 20/45 (44%), Positives = 27/45 (60%)
Query: 372 ENHINRKLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNW 416
E ++ KLP E++L+I SYL LCR A V K ++ LA D W
Sbjct: 133 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILW 177
>AB031230-1|BAA97672.1| 827|Homo sapiens protein containing CXXC
domain 2 protein.
Length = 827
Score = 38.7 bits (86), Expect = 0.058
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 9/136 (6%)
Query: 381 KELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQRC 440
+E+ + + SYL LC C +V + WN D W RIDL + + ++ I +R
Sbjct: 591 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRR- 648
Query: 441 GGFLRQLSL-RGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKI 499
+ +SL +I + L P + DL L+ C I C L+ +
Sbjct: 649 ----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIA--VSALCSSSCPLLRTL 702
Query: 500 NLDSCPSVSDISLKAL 515
++ + D ++ L
Sbjct: 703 DVQWVEGLKDAQMRDL 718
>CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 37.9 bits (84), Expect = 0.10
Identities = 46/192 (23%), Positives = 81/192 (42%), Gaps = 29/192 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ ++ A D G FDTA VY + E +G +K K +R + ITTK+ W
Sbjct: 52 DEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----GWRRSSLVITTKIFW 107
Query: 132 ----NTQH--RRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGL 185
T+ R + + + SL++ L+Y+D+ + P + ET R +
Sbjct: 108 GGKAETERGLSRKHIIEGLKASLERRQLEYVDVVFANRP--------DPNTPMEETVRAM 159
Query: 186 EDAQRMGIVKGIGLSNFNKQQLER---VLKEGTIKPDAI-QIEVHL---QNVQKEMVEFC 238
G+ G S ++ ++ V ++ + P Q E H+ + V+ ++ E
Sbjct: 160 THVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMSQREKVEVQLPELF 219
Query: 239 QSEGVVVMGYSP 250
GV M +SP
Sbjct: 220 HKIGVGAMTWSP 231
>AK223088-1|BAD96808.1| 533|Homo sapiens F-box and leucine-rich
repeat protein 6 isoform 2 variant protein.
Length = 533
Score = 37.9 bits (84), Expect = 0.10
Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 4/114 (3%)
Query: 440 CGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKI 499
C L L L GC + ++ LA++C + L+L + L S+++K+
Sbjct: 212 CCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKL 271
Query: 500 NLDSCPSVSDISLKALADGCPLLTHVNVSW---CQSI-TESGVEALARGCPKLK 549
L + I L CP L + VS SI + VEAL +GCP+L+
Sbjct: 272 WLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQ 325
Score = 33.5 bits (73), Expect = 2.2
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 452 CESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDIS 511
C + + + L PN+ L+L C +IT Q L C +L++++L SD
Sbjct: 362 CNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDL--PCRELEQLHL-GLYGTSD-R 417
Query: 512 LKALADGCPLLTHVNVSWCQSITE 535
L +G P LT WC ++ E
Sbjct: 418 LTLAKEGSPFLTQ---KWCHTLRE 438
>AK026541-1|BAB15499.1| 533|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22888 fis, clone KAT03934. ).
Length = 533
Score = 37.9 bits (84), Expect = 0.10
Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 4/114 (3%)
Query: 440 CGGFLRQLSLRGCESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKI 499
C L L L GC + ++ LA++C + L+L + L S+++K+
Sbjct: 212 CCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKL 271
Query: 500 NLDSCPSVSDISLKALADGCPLLTHVNVSW---CQSI-TESGVEALARGCPKLK 549
L + I L CP L + VS SI + VEAL +GCP+L+
Sbjct: 272 WLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQ 325
Score = 33.5 bits (73), Expect = 2.2
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 452 CESIGDGSMKTLAQSCPNIEDLNLNKCKKITDQTCQALGRRCSKLQKINLDSCPSVSDIS 511
C + + + L PN+ L+L C +IT Q L C +L++++L SD
Sbjct: 362 CNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDL--PCRELEQLHL-GLYGTSD-R 417
Query: 512 LKALADGCPLLTHVNVSWCQSITE 535
L +G P LT WC ++ E
Sbjct: 418 LTLAKEGSPFLTQ---KWCHTLRE 438
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.18
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Query: 77 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 134
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 191
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 192 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 225
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.18
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Query: 77 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 134
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 191
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 192 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 225
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>BC099634-1|AAH99634.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 37.1 bits (82), Expect = 0.18
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 14/93 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ DV+ A + G FDTA VY + E+ +G +K K +R ITTK+ W
Sbjct: 107 DETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK----GWRRSSYVITTKIFW 162
Query: 132 NTQHR------RTEVAQAINDSLKKLGLDYIDL 158
Q R + + + SL++L L Y+D+
Sbjct: 163 GGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>BC096234-1|AAH96234.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 37.1 bits (82), Expect = 0.18
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 14/93 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ DV+ A + G FDTA VY + E+ +G +K K +R ITTK+ W
Sbjct: 107 DETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK----GWRRSSYVITTKIFW 162
Query: 132 NTQHR------RTEVAQAINDSLKKLGLDYIDL 158
Q R + + + SL++L L Y+D+
Sbjct: 163 GGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>BC096232-1|AAH96232.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 37.1 bits (82), Expect = 0.18
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 14/93 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ DV+ A + G FDTA VY + E+ +G +K K +R ITTK+ W
Sbjct: 107 DETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK----GWRRSSYVITTKIFW 162
Query: 132 NTQHR------RTEVAQAINDSLKKLGLDYIDL 158
Q R + + + SL++L L Y+D+
Sbjct: 163 GGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.18
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Query: 77 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 134
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 191
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 192 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 225
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.18
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Query: 77 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 134
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 191
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 192 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 225
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.18
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Query: 77 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 134
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 191
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 192 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 225
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.18
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Query: 77 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 134
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 135 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 191
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 192 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 225
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AF016411-1|AAB92499.1| 404|Homo sapiens KCNA3.1B protein.
Length = 404
Score = 37.1 bits (82), Expect = 0.18
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 14/93 (15%)
Query: 76 DKQLRDVVMRAIDVGYRHFDTASVY---ETEQEIGEAVKMKVEEGVVKREDIFITTKL-W 131
D+ DV+ A + G FDTA VY + E+ +G +K K +R ITTK+ W
Sbjct: 107 DETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK----GWRRSSYVITTKIFW 162
Query: 132 NTQHR------RTEVAQAINDSLKKLGLDYIDL 158
Q R + + + SL++L L Y+D+
Sbjct: 163 GGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>BC125125-1|AAI25126.1| 956|Homo sapiens FBXO10 protein protein.
Length = 956
Score = 36.7 bits (81), Expect = 0.23
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWN--ILALDGSNWQRIDL 421
LP EL IL+YL + L RC+ V + W IL+LD + W+++ L
Sbjct: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCL 50
>AL513165-1|CAI16152.1| 954|Homo sapiens F-box protein 10 protein.
Length = 954
Score = 36.7 bits (81), Expect = 0.23
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWN--ILALDGSNWQRIDL 421
LP EL IL+YL + L RC+ V + W IL+LD + W+++ L
Sbjct: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCL 50
>AK098777-1|BAC05410.1| 554|Homo sapiens protein ( Homo sapiens
cDNA FLJ25911 fis, clone CBR04744. ).
Length = 554
Score = 36.7 bits (81), Expect = 0.23
Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQ 438
LP+ LR+ +L LC C +V + W+ D W R+DL ++ + P++ + +
Sbjct: 313 LPRAAWLRVFQHLGPRELCICMRVCRTWSRWCYDKRLWPRMDLSR-RKSLTPPMLSGVVR 371
Query: 439 R 439
R
Sbjct: 372 R 372
>AF176705-1|AAF03705.1| 551|Homo sapiens F-box protein FBX10
protein.
Length = 551
Score = 36.7 bits (81), Expect = 0.23
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWN--ILALDGSNWQRIDL 421
LP EL IL+YL + L RC+ V + W IL+LD + W+++ L
Sbjct: 22 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCL 66
>AF174598-1|AAF04519.1| 178|Homo sapiens F-box protein Fbx10
protein.
Length = 178
Score = 36.7 bits (81), Expect = 0.23
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWN--ILALDGSNWQRIDL 421
LP EL IL+YL + L RC+ V + W IL+LD + W+++ L
Sbjct: 22 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCL 66
>BC101304-1|AAI01305.1| 394|Homo sapiens FBXW12 protein protein.
Length = 394
Score = 35.9 bits (79), Expect = 0.41
Identities = 17/44 (38%), Positives = 26/44 (59%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDL 421
+LP L RI S+LD+ L + +QV+K WN +A W+ + L
Sbjct: 4 RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
>AY247969-1|AAP75562.1| 464|Homo sapiens putative F-box- and
WD40-repeat-containing protein protein.
Length = 464
Score = 35.9 bits (79), Expect = 0.41
Identities = 17/44 (38%), Positives = 26/44 (59%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDL 421
+LP L RI S+LD+ L + +QV+K WN +A W+ + L
Sbjct: 4 RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
>AC006477-1|AAS00354.1| 117|Homo sapiens unknown protein.
Length = 117
Score = 35.5 bits (78), Expect = 0.54
Identities = 15/62 (24%), Positives = 32/62 (51%)
Query: 481 ITDQTCQALGRRCSKLQKINLDSCPSVSDISLKALADGCPLLTHVNVSWCQSITESGVEA 540
ITD + L +C L +++ C ++D L+ L GC L + + +C +I++ +
Sbjct: 1 ITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQR 60
Query: 541 LA 542
++
Sbjct: 61 MS 62
>BC068566-1|AAH68566.1| 555|Homo sapiens F-box protein 33 protein.
Length = 555
Score = 35.1 bits (77), Expect = 0.71
Identities = 18/69 (26%), Positives = 32/69 (46%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQ 438
LP EL++ I S+L R + W + W ++ + E P +E + +
Sbjct: 71 LPSELIVHIFSFLPAPDRLRASASCSHWRECLFYPALWPQLRICLRVSPAEQPRLEFLMR 130
Query: 439 RCGGFLRQL 447
+CG F+R+L
Sbjct: 131 KCGWFVREL 139
>BC053537-1|AAH53537.1| 555|Homo sapiens F-box protein 33 protein.
Length = 555
Score = 35.1 bits (77), Expect = 0.71
Identities = 18/69 (26%), Positives = 32/69 (46%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENISQ 438
LP EL++ I S+L R + W + W ++ + E P +E + +
Sbjct: 71 LPSELIVHIFSFLPAPDRLRASASCSHWRECLFYPALWPQLRICLRVSPAEQPRLEFLMR 130
Query: 439 RCGGFLRQL 447
+CG F+R+L
Sbjct: 131 KCGWFVREL 139
>BC012385-1|AAH12385.1| 278|Homo sapiens F-box protein 17 protein.
Length = 278
Score = 35.1 bits (77), Expect = 0.71
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 379 LPKELLLRILSYLDVVSL-CRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
LP ELL+++LS++ SL RC V + W + +DG + L R EG + ++
Sbjct: 21 LPPELLVQVLSHVPPRSLVTRCRPVCRAWRDI-VDGPTVWLLQLAR-DRSAEGRALYAVA 78
Query: 438 QRC 440
QRC
Sbjct: 79 QRC 81
>AK057934-1|BAB71616.1| 287|Homo sapiens protein ( Homo sapiens
cDNA FLJ25205 fis, clone REC05844, highly similar to Mus
musculus F-box protein FBX17 mRNA. ).
Length = 287
Score = 35.1 bits (77), Expect = 0.71
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 379 LPKELLLRILSYLDVVSL-CRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
LP ELL+++LS++ SL RC V + W + +DG + L R EG + ++
Sbjct: 30 LPPELLVQVLSHVPPRSLVTRCRPVCRAWRDI-VDGPTVWLLQLAR-DRSAEGRALYAVA 87
Query: 438 QRC 440
QRC
Sbjct: 88 QRC 90
>AF386743-1|AAL37625.1| 278|Homo sapiens F-box protein protein.
Length = 278
Score = 35.1 bits (77), Expect = 0.71
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 379 LPKELLLRILSYLDVVSL-CRCAQVSKLWNILALDGSNWQRIDLFEFQRDVEGPVIENIS 437
LP ELL+++LS++ SL RC V + W + +DG + L R EG + ++
Sbjct: 21 LPPELLVQVLSHVPPRSLVTRCRPVCRAWRDI-VDGPTVWLLQLAR-DRSAEGRALYAVA 78
Query: 438 QRC 440
QRC
Sbjct: 79 QRC 81
>BC029579-1|AAH29579.1| 434|Homo sapiens F-box protein 15 protein.
Length = 434
Score = 34.7 bits (76), Expect = 0.94
Identities = 18/38 (47%), Positives = 23/38 (60%)
Query: 379 LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNW 416
+P E+LL+I SYLD VSL VS+ + LA D W
Sbjct: 1 MPSEILLKIFSYLDAVSLLCTGCVSRRFYHLANDNFIW 38
>BC014679-1|AAH14679.1| 319|Homo sapiens F-box protein 8 protein.
Length = 319
Score = 34.7 bits (76), Expect = 0.94
Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 366 RFTNEDENHINRK-LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
R + E E IN + LP EL ILSYL+ LC S +W LA D WQ
Sbjct: 60 RKSKEQEGFINLEMLPPELSFTILSYLNATDLC---LASCVWQDLANDELLWQ 109
>AY358721-1|AAQ89083.1| 319|Homo sapiens FBXO8 protein.
Length = 319
Score = 34.7 bits (76), Expect = 0.94
Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 366 RFTNEDENHINRK-LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
R + E E IN + LP EL ILSYL+ LC S +W LA D WQ
Sbjct: 60 RKSKEQEGFINLEMLPPELSFTILSYLNATDLC---LASCVWQDLANDELLWQ 109
>AF233224-1|AAF67154.1| 319|Homo sapiens F-box protein FBS protein.
Length = 319
Score = 34.7 bits (76), Expect = 0.94
Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 366 RFTNEDENHINRK-LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
R + E E IN + LP EL ILSYL+ LC S +W LA D WQ
Sbjct: 60 RKSKEQEGFINLEMLPPELSFTILSYLNATDLC---LASCVWQDLANDELLWQ 109
>AF201932-1|AAF86868.1| 319|Homo sapiens DC10 protein.
Length = 319
Score = 34.7 bits (76), Expect = 0.94
Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 366 RFTNEDENHINRK-LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
R + E E IN + LP EL ILSYL+ LC S +W LA D WQ
Sbjct: 60 RKSKEQEGFINLEMLPPELSFTILSYLNATDLC---LASCVWQDLANDELLWQ 109
>AF174596-1|AAF04517.1| 341|Homo sapiens F-box protein Fbx8
protein.
Length = 341
Score = 34.7 bits (76), Expect = 0.94
Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 366 RFTNEDENHINRK-LPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQ 417
R + E E IN + LP EL ILSYL+ LC S +W LA D WQ
Sbjct: 82 RKSKEQEGFINLEMLPPELSFTILSYLNATDLC---LASCVWQDLANDELLWQ 131
>Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats
containing protein protein.
Length = 569
Score = 33.9 bits (74), Expect = 1.6
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 387 ILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
ILSYLD SLC V K W + DG W+++
Sbjct: 160 ILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKL 192
>BC063415-1|AAH63415.1| 412|Homo sapiens F-box and WD repeat domain
containing 4 protein.
Length = 412
Score = 33.9 bits (74), Expect = 1.6
Identities = 19/42 (45%), Positives = 25/42 (59%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
+LP+ELLL I SYLD+ +L R AQV + W+RI
Sbjct: 30 RLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRI 71
>BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 33.9 bits (74), Expect = 1.6
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 387 ILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
ILSYLD SLC V K W + DG W+++
Sbjct: 196 ILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKL 228
>AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 33.9 bits (74), Expect = 1.6
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 387 ILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
ILSYLD SLC V K W + DG W+++
Sbjct: 160 ILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKL 192
>AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 33.9 bits (74), Expect = 1.6
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 387 ILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
ILSYLD SLC V K W + DG W+++
Sbjct: 196 ILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKL 228
>AL627424-2|CAI41027.1| 412|Homo sapiens F-box and WD-40 domain
protein 4 protein.
Length = 412
Score = 33.9 bits (74), Expect = 1.6
Identities = 19/42 (45%), Positives = 25/42 (59%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
+LP+ELLL I SYLD+ +L R AQV + W+RI
Sbjct: 30 RLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRI 71
>AL627144-3|CAI12232.1| 412|Homo sapiens F-box and WD-40 domain
protein 4 protein.
Length = 412
Score = 33.9 bits (74), Expect = 1.6
Identities = 19/42 (45%), Positives = 25/42 (59%)
Query: 378 KLPKELLLRILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
+LP+ELLL I SYLD+ +L R AQV + W+RI
Sbjct: 30 RLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRI 71
>AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 33.9 bits (74), Expect = 1.6
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 387 ILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
ILSYLD SLC V K W + DG W+++
Sbjct: 160 ILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKL 192
>AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 33.9 bits (74), Expect = 1.6
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 387 ILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
ILSYLD SLC V K W + DG W+++
Sbjct: 196 ILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKL 228
>AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 33.9 bits (74), Expect = 1.6
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 387 ILSYLDVVSLCRCAQVSKLWNILALDGSNWQRI 419
ILSYLD SLC V K W + DG W+++
Sbjct: 160 ILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKL 192
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.136 0.410
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 82,871,329
Number of Sequences: 224733
Number of extensions: 3497411
Number of successful extensions: 7977
Number of sequences better than 10.0: 290
Number of HSP's better than 10.0 without gapping: 231
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 6755
Number of HSP's gapped (non-prelim): 758
length of query: 595
length of database: 73,234,838
effective HSP length: 94
effective length of query: 501
effective length of database: 52,109,936
effective search space: 26107077936
effective search space used: 26107077936
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 68 (31.5 bits)
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