BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001344-TA|BGIBMGA001344-PA|IPR011009|Protein kinase-like, IPR002290|Serine/threonine protein kinase, IPR000719|Protein kinase, IPR008271|Serine/threonine protein kinase, active site (255 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 193 2e-50 SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|... 188 9e-49 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 167 1e-42 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 162 4e-41 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 157 2e-39 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 151 1e-37 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 136 2e-33 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 128 1e-30 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 123 2e-29 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 119 4e-28 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 116 3e-27 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 116 3e-27 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 115 6e-27 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 104 1e-23 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 102 6e-23 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 101 8e-23 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 100 2e-22 SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizo... 98 9e-22 SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Sch... 93 5e-20 SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 92 6e-20 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 91 2e-19 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 90 3e-19 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 89 8e-19 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 86 4e-18 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 85 9e-18 SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosac... 85 1e-17 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 84 2e-17 SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosac... 84 2e-17 SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 84 2e-17 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 84 2e-17 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 83 4e-17 SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 83 5e-17 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 82 9e-17 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 80 3e-16 SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosac... 79 5e-16 SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 79 6e-16 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 78 1e-15 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 78 1e-15 SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosa... 76 4e-15 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 76 6e-15 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 75 1e-14 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 75 1e-14 SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 73 5e-14 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 72 7e-14 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 72 9e-14 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 71 1e-13 SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 71 2e-13 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 71 2e-13 SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizo... 70 3e-13 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 70 4e-13 SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase ... 70 4e-13 SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizo... 69 5e-13 SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase... 69 7e-13 SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 69 9e-13 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 67 2e-12 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 67 2e-12 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 67 3e-12 SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Sch... 67 3e-12 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 66 4e-12 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 66 4e-12 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 66 5e-12 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 66 5e-12 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 65 8e-12 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 65 1e-11 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 63 4e-11 SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|S... 63 4e-11 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 62 8e-11 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 61 2e-10 SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomy... 60 4e-10 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 59 5e-10 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 59 7e-10 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 58 1e-09 SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosa... 58 2e-09 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 58 2e-09 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 57 3e-09 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 57 3e-09 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 56 7e-09 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 55 9e-09 SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schiz... 52 8e-08 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 51 2e-07 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 50 2e-07 SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces p... 49 6e-07 SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Pp... 48 1e-06 SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosac... 48 2e-06 SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizo... 46 4e-06 SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schiz... 46 5e-06 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 44 2e-05 SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosa... 43 4e-05 SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosacchar... 43 5e-05 SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosac... 43 5e-05 SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizos... 42 7e-05 SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosa... 42 9e-05 SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces po... 41 2e-04 SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizos... 41 2e-04 SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizo... 39 6e-04 SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 39 8e-04 SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schiz... 36 0.004 SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizos... 36 0.006 SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosa... 35 0.010 SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizos... 35 0.010 SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schi... 34 0.023 SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizo... 34 0.023 SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizos... 33 0.031 SPAC23A1.19c ||SPAC26H5.01c|RecQ type DNA helicase Hrq1 |Schizos... 30 0.38 SPCC1322.12c |bub1||serine/threonine protein kinase Bub1|Schizos... 29 0.66 SPAC22H10.05c |||mRNA cleavage and polyadenylation specificity f... 26 6.1 SPCC417.08 |tef3||translation elongation factor eEF3|Schizosacch... 26 6.1 SPCC1739.11c |cdc11||SIN component scaffold protein Cdc11|Schizo... 26 6.1 SPCC24B10.21 |tpi1|tpi|triosephosphate isomerase|Schizosaccharom... 25 8.1 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 193 bits (471), Expect = 2e-50 Identities = 97/232 (41%), Positives = 151/232 (65%), Gaps = 16/232 (6%) Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQL-E 85 + Y+++ IG G YG VYKAR +G +IVAMKK+++ +G+P + +REI+LL+++ + Sbjct: 2 ENYQKVEKIGEGTYGVVYKARHKLSG-RIVAMKKIRLEDESEGVPSTAIREISLLKEVND 60 Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSR----APGPLPESRIR 141 N VRLLD+ H + L+LVFE ++ DL ++ R L ++ Sbjct: 61 ENNRSNCVRLLDILHA--------ESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQ 112 Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVT 200 ++ +++GV+F HS RI+HRDLKP NLL+ G +KLADFGLA+++ V ++ T +VT Sbjct: 113 KFTYQLVNGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIVT 172 Query: 201 LWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251 LWYR PEVLLG+R Y + +D+WS GC+ A++ R PL PG S+ D++ +IF+ Sbjct: 173 LWYRAPEVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQ 224 >SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|Schizosaccharomyces pombe|chr 3|||Manual Length = 288 Score = 188 bits (457), Expect = 9e-49 Identities = 94/227 (41%), Positives = 154/227 (67%), Gaps = 17/227 (7%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 Y+ L +G G Y VYK ++ G +IVA+K +++ ++G P + +REI+L+++L R Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTG-EIVALKVIRID-ADEGTPSTAIREISLMKEL---R 57 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRA--PGPLPESRIRSMSHD 146 HPNI+ L DV L+ + +L+L VFE++E+DL ++ G LP S++++ + Sbjct: 58 HPNIMSLSDV------LQTENKLML--VFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQ 109 Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYRP 205 ++ G+ F H +R++HRDLKP NLL+ G +KLADFGLA++ + + ++ VVTLWYR Sbjct: 110 LLKGISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRA 169 Query: 206 PEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251 P+VLLG+R Y +++D+WS GC++A++ T RPL G+++ DQL +IFR Sbjct: 170 PDVLLGSRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFR 216 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 167 bits (407), Expect = 1e-42 Identities = 92/224 (41%), Positives = 133/224 (59%), Gaps = 12/224 (5%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 YE L I G+YG VY+ D + +VA+KK+K G P++++REI L + R Sbjct: 74 YEILEKIEEGSYGIVYRGLD-KSTNTLVALKKIKFDPNGIGFPITSLREI---ESLSSIR 129 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148 H NIV L V G + ++LV E +E DL + L P +S ++++ ++ Sbjct: 130 HDNIVELEKVVVGKDLKD------VYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLL 183 Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK-TYDVEMKLTSVVVTLWYRPPE 207 + F+H H +HRDLKP NLL+ G +KLADFGLA+ + + LT +VVTLWYR PE Sbjct: 184 AATAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPE 243 Query: 208 VLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250 +LLGA Y +D+WS GC+ A++ TR PL G S+ DQL++IF Sbjct: 244 LLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIF 287 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 162 bits (394), Expect = 4e-41 Identities = 86/225 (38%), Positives = 137/225 (60%), Gaps = 15/225 (6%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 YE++ IG G YG VYKA + G +VA+K++++ +DG P++TVRE+ +L++L R Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTG-DLVALKRIRLEQEKDGFPITTVREVKILQRL---R 332 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148 H NIVRLL++ +E+ +++VFE+++ DL L + I+ +S I Sbjct: 333 HKNIVRLLEIM-----VEKSS---VYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIF 384 Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK--TYDVEMKLTSVVVTLWYRPP 206 + +LH ++HRD+K N+L+ G +K ADFGLA+ T T+ V+TLW+RPP Sbjct: 385 EALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPP 444 Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250 E+LLG Y +A+D+WSAGC++ +L T +P G + QL I+ Sbjct: 445 ELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIY 489 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 157 bits (380), Expect = 2e-39 Identities = 84/219 (38%), Positives = 128/219 (58%), Gaps = 13/219 (5%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94 +G G Y V+ R + VA+KK+KV +DGI +S +REI LR+ RH N++ Sbjct: 17 VGEGTYAVVFLGRQKETNRR-VAIKKIKVGQFKDGIDISALREIKFLRES---RHDNVIE 72 Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154 L+DV L ++ E ++ DL+ + + I+S ++ G+ + Sbjct: 73 LVDVFSTKSNLN--------IILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHI 124 Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGAR- 213 HS I+HRDLKP+NLL++ G +KLADFGL++ + ++ V+T WYRPPE+ +G R Sbjct: 125 HSRFILHRDLKPNNLLISSDGVLKLADFGLSRDFGTPSHMSHQVITRWYRPPELFMGCRS 184 Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252 Y + +D+WS GC+ A+L R P LPG SD DQL+ IFR+ Sbjct: 185 YGTGVDMWSVGCIFAELMLRTPYLPGESDLDQLNVIFRA 223 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 151 bits (365), Expect = 1e-37 Identities = 81/238 (34%), Positives = 135/238 (56%), Gaps = 19/238 (7%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 Y + +G G +G VYK++ G++ A+K++ + ++G P++ +REI +L+ + + Sbjct: 36 YHLMEKLGEGTFGEVYKSQR-RKDGKVYALKRILMHTEKEGFPITAIREIKILKSI---K 91 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148 H NI+ L D+ + ++ +++V +++ DL L E +I+ + Sbjct: 92 HENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLF 151 Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE--------------MKL 194 +G +LH I+HRDLK NLL+ G +K+ADFGLA+ E + Sbjct: 152 AGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRREY 211 Query: 195 TSVVVTLWYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251 T VVT WYR PE+LLG RY +A+D+WS GC++A+++ RP+L G+SD DQL +IFR Sbjct: 212 TGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFR 269 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 136 bits (330), Expect = 2e-33 Identities = 86/230 (37%), Positives = 128/230 (55%), Gaps = 17/230 (7%) Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHN-GGQIVAMKKVKVALTEDGIPLSTVREIALL 81 F+ ++YE ++LIG GAYG V A LH G VA+KK+ L T+REI LL Sbjct: 33 FELPEEYEMINLIGQGAYGVVCAA--LHKPSGLKVAVKKIH-PFNHPVFCLRTLREIKLL 89 Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141 R +RH NI+ +LD+ E + +++V E +E DL + P L + + Sbjct: 90 RH---FRHENIISILDILPPPSYQELED---VYIVQELMETDLYRVIRSQP--LSDDHCQ 141 Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSV 197 ++ I+ + +HS +VHRDLKP NLL+ +K+ADFGLA++ + +T Sbjct: 142 YFTYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEY 201 Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246 V T WYR PE++L R Y A+D+WS GC+LA++ + RPL PG Q+ Sbjct: 202 VATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQI 251 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 128 bits (308), Expect = 1e-30 Identities = 86/228 (37%), Positives = 128/228 (56%), Gaps = 28/228 (12%) Query: 29 YEELSLIGTGAYGTVYKARDLH-NGGQIVAMKKVKVA-------LTEDGIPLSTVREIAL 80 Y+ + I +G YG VYKA + N ++ A+KK K + G+ S +RE+ L Sbjct: 5 YKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMML 64 Query: 81 LRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDS---FLSRA-PGPLP 136 R+++ H NIV L+ V L +D + +VFE+ E DL F SR+ +P Sbjct: 65 CREIQ---HENIVSLVQV------LLKDG--TISMVFEYAEHDLLQIIHFHSRSRTRQIP 113 Query: 137 ESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DVEMKLT 195 S ++S+ II+GV +LH + I+HRDLKP N+++T G+VK+ D GL + D + Sbjct: 114 PSILKSILWQIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFY 173 Query: 196 S---VVVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPG 239 S VVVT+WYR PE+LLGA Y A+DVW+ GC+ ++ PL G Sbjct: 174 SSDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKG 221 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 123 bits (297), Expect = 2e-29 Identities = 78/224 (34%), Positives = 121/224 (54%), Gaps = 16/224 (7%) Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82 F+ +Y +L IG GA+G V A+D G VA+KK+ + + T RE+ LL+ Sbjct: 14 FEITTRYSDLQPIGMGAFGLVCSAKDQLTGMN-VAVKKIMKPFSTPVLAKRTYRELKLLK 72 Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142 L RH NI+ L D+ + + + + V E + DL L+ P L I+ Sbjct: 73 HL---RHENIISLSDIF-----ISPFEDI--YFVTELLGTDLHRLLTSRP--LETQFIQY 120 Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLW 202 + I+ G+ F+HS ++HRDLKP N+L+ +K+ DFGLA+ D +M T V T + Sbjct: 121 FLYQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQM--TGYVSTRY 178 Query: 203 YRPPEVLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQ 245 YR PE++L +Y +D+WSAGC+ A++ +PL PG +Q Sbjct: 179 YRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQ 222 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 119 bits (287), Expect = 4e-28 Identities = 74/222 (33%), Positives = 120/222 (54%), Gaps = 14/222 (6%) Query: 35 IGTGAYGTVYKARDLHNGGQ-IVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93 +G GAYG V AR++ + Q VA+KK+ ++ + +REI LL +R+ + Sbjct: 27 LGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIHFRNHRNITCI 86 Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDF 153 LD+ + E +++ E +E DL++ + ++ PL ++ +S + I+ G+ + Sbjct: 87 YDLDIINPYNFNE------VYIYEELMEADLNAII-KSGQPLTDAHFQSFIYQILCGLKY 139 Query: 154 LHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-----LTSVVVTLWYRPPEV 208 +HS ++HRDLKP NLLV +K+ DFGLA+ + +T V T WYR PE+ Sbjct: 140 IHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGFMTEYVATRWYRAPEI 199 Query: 209 LLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249 +L + Y +DVWS GC+LA+L PL G QL+ I Sbjct: 200 MLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLI 241 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 116 bits (280), Expect = 3e-27 Identities = 78/227 (34%), Positives = 121/227 (53%), Gaps = 15/227 (6%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 YE ++G+G++G V +A+ + G +A+K+V +D + RE+ ++R A Sbjct: 25 YEPCRVLGSGSFGVVIQAKLVGTPG-FIAVKRV----LQDKRYKN--RELQIMR---AIS 74 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVF--EHVEQDLDSFLSRAPGPLPESRIRSMSHD 146 HPNI++L+ H + + L L L + E V D+ + R +P I+ + Sbjct: 75 HPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKS-IPNLSIKLYAFQ 133 Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTV-AGRVKLADFGLAKTYDVEMKLTSVVVTLWYRP 205 + + +LHS + HRD+KP NLLV G +KL DFG AK S + + +YR Sbjct: 134 LFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSEPNVSYICSRYYRA 193 Query: 206 PEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251 PE++ GA Y + +DVWSA CV+A+L RPL PG S +QL I R Sbjct: 194 PELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIR 240 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 116 bits (279), Expect = 3e-27 Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 22/228 (9%) Query: 35 IGTGAYGTVYKARDLHNGG--QIVAMKKVK-VALTEDGIPLSTVREIALLRQLEAYRHPN 91 +G G++GTVY A+ G + VA+KK+K + + L +RE LR++ +HP Sbjct: 27 LGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRKIS--KHPC 84 Query: 92 IVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPL-PESRIRSMSHDIISG 150 ++ LL+ D +FLV E ++ +L R G L + ++ IISG Sbjct: 85 LIDLLETF-------MDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISG 137 Query: 151 VDFLHSHRIVHRDLKPHNLLVT------VAGR--VKLADFGLAKTYDVEMKLTSVVVTLW 202 ++ +H H +HRD+KP N+LV ++ R +KL DFGLA+ LT V T W Sbjct: 138 IEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLTEYVSTRW 197 Query: 203 YRPPEVLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249 YR PE+LL Y ++D+++ GC++ ++++ +PL PG +++DQL+R+ Sbjct: 198 YRAPELLLRSGSYNHSVDLYAFGCIVFEIYSLKPLFPGRNETDQLNRV 245 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 115 bits (277), Expect = 6e-27 Identities = 73/228 (32%), Positives = 122/228 (53%), Gaps = 17/228 (7%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 Y + +G G +G+VY A ++VA+K +K L + + +RE+ L +L Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVS-DATRLREVHSLLRLS--E 92 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLS-RAPGPLPESRIRSMSHDI 147 + NIV + D L DQ L +V E ++ +L +S R PL +++ + I Sbjct: 93 NENIVNIFD-------LYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQI 145 Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAG-----RVKLADFGLAKTYDVEMKLTSVVVTLW 202 G++ +H++ HRD+KP N+L++ VK+ADFGLA+ + T V T W Sbjct: 146 FKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRW 205 Query: 203 YRPPEVLLGARYCS-ALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249 YR PE+LL Y S +D+++AGC+ ++ T +P+ PG D DQL+++ Sbjct: 206 YRAPELLLRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKM 253 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 104 bits (250), Expect = 1e-23 Identities = 71/222 (31%), Positives = 115/222 (51%), Gaps = 14/222 (6%) Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87 +YE + +G G++G V K D H GQ+VA+K +K G L V + L + + Sbjct: 517 RYEIIDTVGKGSFGQVLKCID-HKRGQVVAIKVIKNRQKFHGQTLVEVGILKRLCEADPA 575 Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDL-DSFLSRAPGPLPESRIRSMSHD 146 N++R L D + L +V E + +L D LP ++S + Sbjct: 576 DKNNVIRYLS--------HFDFRGHLCIVTELLGSNLFDVIRENNYKGLPLIVVKSFALQ 627 Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVT--VAGRVKLADFGLAKTYDVEMKLTSVVVTLWYR 204 + + L I+H DLKP NLL++ + R+KL DFG + Y+ K+ + + + +YR Sbjct: 628 GLQALRLLQGQNIIHCDLKPENLLLSHPLKARIKLIDFGSSCFYNE--KVYTYLQSRFYR 685 Query: 205 PPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246 PE++LG Y +D+WS GC+LA+L T PL PG ++++QL Sbjct: 686 APEIILGLEYGKEIDIWSFGCILAELFTGVPLFPGGNETEQL 727 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 102 bits (244), Expect = 6e-23 Identities = 83/237 (35%), Positives = 128/237 (54%), Gaps = 29/237 (12%) Query: 15 SINDVSALFQNAQ-KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---- 69 +I S + QNA K+ + LIG G YG V+ A ++ N G+++A+K+V++ T +G Sbjct: 810 TITSGSVVSQNATFKWMKGELIGNGTYGKVFLAMNI-NTGELIAVKQVEIPQTINGRHDQ 868 Query: 70 ----IPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLD 125 I S EI+++ L+ H NIV+ L G + E D + +FL E+V Sbjct: 869 LRKDIVDSINAEISMIADLD---HLNIVQYL----GFEKTETD--ISIFL--EYVSGGSI 917 Query: 126 SFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLA 185 R GP E +R +S ++ G+ +LHS I+HRDLK NLL+ G K++DFG++ Sbjct: 918 GRCLRNYGPFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGIS 977 Query: 186 K----TYDVEMKLTSVVVTLWYRPPEVLLGAR--YCSALDVWSAGC-VLAQLHTRRP 235 K YD + L S+ ++++ PEV+ Y + +DVWS GC VL L RRP Sbjct: 978 KHSDNVYDNDANL-SMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRRP 1033 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 101 bits (243), Expect = 8e-23 Identities = 66/202 (32%), Positives = 112/202 (55%), Gaps = 15/202 (7%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVR-EIALLRQLEAYRHPNIV 93 +G GA+G VY+ ++ NG + VA+KKVK++ LS ++ EI LL+ L+ HPNIV Sbjct: 15 LGKGAFGAVYRGLNIKNG-ETVAVKKVKLSKMLKS-DLSVIKMEIDLLKNLD---HPNIV 69 Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDF 153 + + G D L ++ E+ E + + G +PE+ + + ++ G+ + Sbjct: 70 K-----YRGSYQTNDS---LCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLY 121 Query: 154 LHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGAR 213 LH+ ++HRD+K N+L T G +KLADFG+A + ++ SVV + ++ PEV+ Sbjct: 122 LHNQGVIHRDIKGANILTTKDGTIKLADFGVATKINA-LEDHSVVGSPYWMAPEVIELVG 180 Query: 214 YCSALDVWSAGCVLAQLHTRRP 235 +A D+WS GC + +L P Sbjct: 181 ATTASDIWSVGCTVIELLDGNP 202 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 100 bits (240), Expect = 2e-22 Identities = 68/228 (29%), Positives = 117/228 (51%), Gaps = 17/228 (7%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 Y ++G+G++G V + + + + A+K+V +D RE+ ++R + + Sbjct: 32 YTSSKVVGSGSFGVVMQVHLIESDSK-AAIKRV----LQD--KRFKNRELQIMRIM---K 81 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDL---DSFLSRAPGPLPESRIRSMSH 145 HPNIV L+ + + ++ L LV E + + + +R +P ++ + Sbjct: 82 HPNIVDLIAYYYTTG--DNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIY 139 Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVA-GRVKLADFGLAKTYDVEMKLTSVVVTLWYR 204 ++ + ++H+ I HRD+KP NLL+ G +KL DFG AK S + + +YR Sbjct: 140 QLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNVSYICSRYYR 199 Query: 205 PPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251 PE++ GA Y A+D+WS GCV+A+L PL PG S DQL I + Sbjct: 200 APELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIK 247 >SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizosaccharomyces pombe|chr 1|||Manual Length = 534 Score = 98.3 bits (234), Expect = 9e-22 Identities = 78/240 (32%), Positives = 119/240 (49%), Gaps = 14/240 (5%) Query: 13 VASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPL 72 V +ND+ +KY L +G G +G V + +DL QIVA+K +K + Sbjct: 115 VLYVNDLLGT-DEGRKYLILDTLGHGTFGQVARCQDLKTQ-QIVAIKVIK---NKPAFYN 169 Query: 73 STVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAP 132 V E+++L L P R L + Q + ++ L LVFE + +L + + Sbjct: 170 QCVMEVSILELLNNKYDPEDKRHLIRLYD-QFMHKNH---LCLVFELLSINLYELIKQNQ 225 Query: 133 -GPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGR--VKLADFGLAKTYD 189 L S +RS + ++S L RI+H DLKP N+L+ VK+ DFG A Sbjct: 226 FRGLHLSLVRSFATQLLSCTSLLKQARIIHCDLKPENILLQDLSSPIVKVIDFGSA--CH 283 Query: 190 VEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249 + + + + +YR PEV+LG Y +D+WS GC+LA+L PL PG S+ +QL RI Sbjct: 284 ERQTVYTYIQSRFYRSPEVILGLHYNCGIDMWSLGCILAELFLGLPLFPGNSEYNQLCRI 343 >SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Schizosaccharomyces pombe|chr 1|||Manual Length = 332 Score = 92.7 bits (220), Expect = 5e-20 Identities = 71/237 (29%), Positives = 124/237 (52%), Gaps = 24/237 (10%) Query: 18 DVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIV--AMKKVKVALTEDGIPLSTV 75 ++ +F YE + +G G Y V++ ++ N + + +K VK + Sbjct: 32 NMQEVFGYQDNYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVLKPVKYKKIK-------- 83 Query: 76 REIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPL 135 REI +L+ L PNI+ LLD+ + + L+FE V+ ++D F + P L Sbjct: 84 REIKILQNLAG--GPNIISLLDI------VRDPESKTPSLIFEFVD-NID-FRTLYP-TL 132 Query: 136 PESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGR-VKLADFGLAKTYDVEMKL 194 + IR S++++ +DF HS I+HRD+KPHN+++ R ++L D+GLA+ Y M+ Sbjct: 133 SDYDIRYYSYELLKALDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYHAGMEY 192 Query: 195 TSVVVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRR-PLLPGASDSDQLHRI 249 V + +++ PE+L+ R Y +LD+WS G + A L ++ G + DQL +I Sbjct: 193 NVRVASRYFKGPELLVDFREYDYSLDIWSFGVMFAALIFKKDTFFRGRDNYDQLVKI 249 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 92.3 bits (219), Expect = 6e-20 Identities = 73/227 (32%), Positives = 115/227 (50%), Gaps = 26/227 (11%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGG----QIVAMKKVKVALTEDGIPLSTVREIALLRQL 84 YE + +G+G + V A ++++G +I+ +K+ + +E REI +L+ L Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSL 226 Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAPGPLPESRIRSM 143 HP +V+ CH + E D +L F+V E+VE DL FL A G + E + + Sbjct: 227 H---HPGVVQ----CH--EIFENDDEL--FIVMEYVEGGDLMDFLI-ANGSIDEQDCKPL 274 Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKT-YDVEMKLTSVVVTLW 202 ++ + LH + HRD+KP N+L+T +K++DFGLAK + L + T+ Sbjct: 275 LKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMG 334 Query: 203 YRPPEVL------LGARYCSALDVWSAGCVLAQLHTRRPLLPGASDS 243 Y PEVL L Y +D+WS GCVL + T +P AS S Sbjct: 335 YLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTAS--IPFASSS 379 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 90.6 bits (215), Expect = 2e-19 Identities = 63/224 (28%), Positives = 119/224 (53%), Gaps = 14/224 (6%) Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLE 85 A +YE + +G G++G V + D + G++VA+K ++ + + + E +L+++ Sbjct: 696 AYRYEVVDFLGKGSFGQVLRCID-YETGKLVALKIIR---NKKRFHMQALVETKILQKIR 751 Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGPLPESRIRSMS 144 + + V + RD L + E + ++L + S LP I+S++ Sbjct: 752 EW--DPLDEYCMVQYTDHFYFRDH---LCVATELLGKNLYELIKSNGFKGLPIVVIKSIT 806 Query: 145 HDIISGVDFLHSHRIVHRDLKPHNLLVT--VAGRVKLADFGLAKTYDVEMKLTSVVVTLW 202 +I + L+ ++H DLKP N+L+ +VK+ DFG + ++ E T + + + Sbjct: 807 RQLIQCLTLLNEKHVIHCDLKPENILLCHPFKSQVKVIDFG-SSCFEGECVYT-YIQSRF 864 Query: 203 YRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246 YR PEV+LG Y + +DVWS GC++A+++T PL PG ++ +QL Sbjct: 865 YRSPEVILGMGYGTPIDVWSLGCIIAEMYTGFPLFPGENEQEQL 908 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 89.8 bits (213), Expect = 3e-19 Identities = 71/234 (30%), Positives = 125/234 (53%), Gaps = 28/234 (11%) Query: 33 SLIGTGAYGTVYKARDLHNGGQIVAMKKV---KVALTEDG---IPLSTVREIALLRQLEA 86 +LIG+G++G VY + + G+++A+K+V V+ ++D + + EIALL++L Sbjct: 398 ALIGSGSFGQVYLGMNA-SSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELS- 455 Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146 H +IV+ L G L D L +FL E+V + L G E+ +++ Sbjct: 456 --HEHIVQYL-----GSNLNSDH-LNIFL--EYVPGGSVAGLLTMYGSFEETLVKNFIKQ 505 Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLT-------SVVV 199 + G+++LHS IVHRD+K N+LV G++K++DFG++K ++ T S Sbjct: 506 TLKGLEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQG 565 Query: 200 TLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRSG 253 + ++ PEV+ + D+WS GC++ ++ T + P + DQ+ IFR G Sbjct: 566 SSFWMAPEVVKQTMHTEKTDIWSLGCLVIEMLTSKHPYP---NCDQMQAIFRIG 616 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 88.6 bits (210), Expect = 8e-19 Identities = 58/209 (27%), Positives = 104/209 (49%), Gaps = 13/209 (6%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 Y +L L+G G+YG VY+ + + VA+K + + ED + +E+A+L +L+ Sbjct: 10 YTKLELVGRGSYGAVYRGI-CNLTKETVAIKILNLDTDEDEVS-DIQKEVAVLSELKQSD 67 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148 NI++ HG + + L+++ ++ L A GP+ E I + + + Sbjct: 68 VENIIKY----HGSYLVGTN----LWIIMDYCHGGSVRTLMEA-GPISEPCISLILRETL 118 Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV--EMKLTSVVVTLWYRPP 206 + F+H I+HRD+K N+LV+++G VKL DFG+A ++ ++T + W P Sbjct: 119 QALKFIHHAGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKRITFIGTPYWMAPE 178 Query: 207 EVLLGARYCSALDVWSAGCVLAQLHTRRP 235 + G Y D+WS G ++ T P Sbjct: 179 VIRDGQEYNVMADIWSLGITAYEIATGSP 207 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 86.2 bits (204), Expect = 4e-18 Identities = 65/212 (30%), Positives = 101/212 (47%), Gaps = 19/212 (8%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKV-KVALTEDGIPLSTVREIALLRQLEAY 87 Y IG G + ++ +D N G I A K + K +L D L EI + + + Sbjct: 41 YTRYDCIGEGGFARCFRVKD--NYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMS-- 96 Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147 HPNIV +D C E + +L+ E E L R L E +R + I Sbjct: 97 -HPNIVGFID------CFEDSTNI--YLILELCEHKSLMELLRKRKQLTEPEVRYLMMQI 147 Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY--DVEMKLTSVVVTLWYRP 205 + + ++H R++HRDLK N+++ + VK+ DFGLA D E K+T + T Y Sbjct: 148 LGALKYMHKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEERKMT-ICGTPNYIA 206 Query: 206 PEVLLGAR--YCSALDVWSAGCVLAQLHTRRP 235 PE+L ++ + +D+WSAG V+ L +P Sbjct: 207 PEILFNSKEGHSFEVDLWSAGVVMYALLIGKP 238 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 85.0 bits (201), Expect = 9e-18 Identities = 67/197 (34%), Positives = 99/197 (50%), Gaps = 18/197 (9%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94 IG G+ G V ++ G + A+K + + RE L R L RHPNI R Sbjct: 59 IGAGSMGKVKLVVNILTGEK-AALKMIPFTPNNTSQTVRVQREALLGRLL---RHPNICR 114 Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVE--QDLDSFLSRAPGPLPESRIRSMSHDIISGVD 152 ++D C +++FE+V Q L+ L+R G L E RS + +I+ + Sbjct: 115 VIDCIRTPACT--------YILFEYVPGGQLLEYILAR--GKLDEDLARSFAMQLINALV 164 Query: 153 FLHSHRIVHRDLKPHNLLVTVAGR-VKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG 211 +LH + IVHRDLK N+L+T R VKL DFGL+ Y + L + +L++ PE+L Sbjct: 165 YLHKNFIVHRDLKIENVLLTQDSRQVKLIDFGLSNFYSKDDLLRTYCGSLYFAAPELLDA 224 Query: 212 ARYCS-ALDVWSAGCVL 227 Y +DVWS G V+ Sbjct: 225 KPYIGPEVDVWSLGVVI 241 >SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosaccharomyces pombe|chr 3|||Manual Length = 477 Score = 84.6 bits (200), Expect = 1e-17 Identities = 57/220 (25%), Positives = 108/220 (49%), Gaps = 9/220 (4%) Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87 +Y S +G G + TV A D N Q A+K ++ + + ++E+++L +L+A Sbjct: 158 RYIVQSNLGKGMFSTVVSALD-RNRNQTFAIKIIR---NNEVMYKEGLKEVSILERLQAA 213 Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147 ++ + + ++ ++F + +D+ R G L +R ++ + Sbjct: 214 DREGKQHIIH--YERHFMHKNHLCMVFEMLSLNLRDILKKFGRNVG-LSIKAVRLYAYQM 270 Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRV-KLADFGLAKTYDVEMKLTSVVVTLWYRPP 206 +D L ++H D+KP N+LV + K+ D G A E ++T +V+ +YR P Sbjct: 271 FMALDLLKQCNVIHSDIKPDNMLVNEKRNILKICDLGSASDAS-ENEITPYLVSRFYRAP 329 Query: 207 EVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246 E++LG Y +D WS GC L +L+T + L PG +++ L Sbjct: 330 EIILGFPYSCPIDTWSVGCSLYELYTGQILFPGRTNNQML 369 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 84.2 bits (199), Expect = 2e-17 Identities = 61/183 (33%), Positives = 89/183 (48%), Gaps = 16/183 (8%) Query: 48 DLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLER 107 D+ + + K A +E + TVRE AL L RHP I DV Sbjct: 162 DITKAKAAASAEATKAAQSEKNKEIRTVREAALSTLL---RHPYICEARDVYITNSHY-- 216 Query: 108 DQQLVLFLVFEHVE--QDLDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLK 165 ++VFE V+ Q LD +S G L E + R I S + +LH + +VHRDLK Sbjct: 217 ------YMVFEFVDGGQMLDYIISH--GKLKEKQARKFVRQIGSALSYLHQNSVVHRDLK 268 Query: 166 PHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGARYCS-ALDVWSAG 224 N+L++ G +K+ DFGL+ Y + +L + +L++ PE+L Y +DVWS G Sbjct: 269 IENILISKTGDIKIIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNAQPYIGPEVDVWSFG 328 Query: 225 CVL 227 VL Sbjct: 329 IVL 331 >SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 436 Score = 84.2 bits (199), Expect = 2e-17 Identities = 70/231 (30%), Positives = 113/231 (48%), Gaps = 18/231 (7%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVK---VALTEDGIPLSTVREIALLRQLE 85 ++ L+++G G+YG V + N G++ A K++K + L G+ T E +L ++ Sbjct: 91 FQPLTVLGRGSYGKVLLVKQ-KNTGRLFAQKQLKKASIVLRAKGLE-QTKNERQILEEV- 147 Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAPGPLPESRIRSMS 144 RHP I RL + Q +R L+L+ ++ +L S L+ LPE + + Sbjct: 148 --RHPFICRLY---YAFQDHDR-----LYLILQYAPGGELFSHLAEQR-MLPEDVVAFYT 196 Query: 145 HDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYR 204 ++ + LH IV+RDLKP N L+ G + L DFGL+K + S V T Y Sbjct: 197 AELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADCRSFVGTEEYC 256 Query: 205 PPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRSGPS 255 PE+LL Y A+D WS G ++ L T P + + +I R+ P+ Sbjct: 257 APEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPN 307 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 83.8 bits (198), Expect = 2e-17 Identities = 65/231 (28%), Positives = 108/231 (46%), Gaps = 18/231 (7%) Query: 7 SQSPPVVASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALT 66 S V+A + + Y IG GA G VY AR + VA+KK+ + Sbjct: 364 SNDSAVLAKLQSICNPKNPTLLYRNFVKIGQGASGDVYSARQVGTNLS-VAIKKMNI--N 420 Query: 67 EDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLD 125 + V EI +++ ++ H NIV +D + L++V E++ L Sbjct: 421 QQPKKEFIVNEILVMK---SHHHKNIVNFIDTFF--------YKSELWMVMEYMRGGSLT 469 Query: 126 SFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLA 185 ++ L E +I ++ + + G+ LH + IVHRD+K N+L+++ G +KL DFG Sbjct: 470 EVVTN--NTLSEGQIAAICKETLEGLQHLHENGIVHRDIKSDNILLSLQGDIKLTDFGFC 527 Query: 186 KTYDVEM-KLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRP 235 D M K T++V T ++ PEV+ Y +DVWS G + ++ P Sbjct: 528 AQIDSNMTKRTTMVGTPYWMAPEVVTRKEYGFKVDVWSLGIMAIEMVEGEP 578 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 83.8 bits (198), Expect = 2e-17 Identities = 60/191 (31%), Positives = 96/191 (50%), Gaps = 14/191 (7%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKV-KVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93 +G G +G VY A++ G IVA+K + K L + I REI + L RH NI+ Sbjct: 95 LGKGKFGRVYLAKEKKTGF-IVALKTLHKSELVQSKIEKQVRREIEIQSNL---RHKNIL 150 Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDF 153 RL H ++++ L L F +L L RA E + + + + Sbjct: 151 RLYGHFHD------EKRIYLILEFAG-RGELYQHLRRAKR-FSEEVASKYIFQMANALSY 202 Query: 154 LHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGAR 213 LH ++HRD+KP N+L+ + G +KL+DFG + + + T++ TL Y PPE++ G Sbjct: 203 LHKKHVIHRDIKPENILLGIDGEIKLSDFGWS-VHAPSNRRTTLCGTLDYLPPEMVEGKE 261 Query: 214 YCSALDVWSAG 224 + +D+WS G Sbjct: 262 HTEKVDLWSLG 272 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 83.0 bits (196), Expect = 4e-17 Identities = 60/215 (27%), Positives = 101/215 (46%), Gaps = 17/215 (7%) Query: 32 LSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPN 91 ++ +G G G+V K R G Q++ K +A + +RE+ + R + P Sbjct: 82 MNSLGEGVSGSVRKCRI--RGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCTS---PY 136 Query: 92 IVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAP---GPLPESRIRSMSHDI 147 IV+ C+ + + L + E+ LD+ R G E + ++ + Sbjct: 137 IVKYYGACYN------NAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGV 190 Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPE 207 +SG+ +LH +I+HRD+KP N+L+T G+VKL DFG++ V + T +Y PE Sbjct: 191 LSGLSYLHDRKIIHRDIKPSNILLTSKGQVKLCDFGVSGEL-VNSLAGTFTGTSYYMAPE 249 Query: 208 VLLGARYCSALDVWSAGCVLAQLHTRR-PLLPGAS 241 + G Y + D+WS G L ++ R P P S Sbjct: 250 RISGGSYTISSDIWSLGLTLMEVALNRFPFPPEGS 284 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 82.6 bits (195), Expect = 5e-17 Identities = 64/195 (32%), Positives = 98/195 (50%), Gaps = 15/195 (7%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKV-KVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93 +G G++G V K + Q VA+K + + L + + + REI+ L+ L RHP+I+ Sbjct: 40 LGEGSFGKV-KLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLL---RHPHII 95 Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDF 153 +L DV + +V+ V E+ +L ++ + E R II +++ Sbjct: 96 KLYDV------ITTPTDIVM--VIEYAGGELFDYIVEKKR-MTEDEGRRFFQQIICAIEY 146 Query: 154 LHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGAR 213 H H+IVHRDLKP NLL+ VK+ADFGL+ L + + Y PEV+ G Sbjct: 147 CHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKL 206 Query: 214 YCS-ALDVWSAGCVL 227 Y +DVWS G VL Sbjct: 207 YAGPEVDVWSCGIVL 221 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 81.8 bits (193), Expect = 9e-17 Identities = 59/208 (28%), Positives = 108/208 (51%), Gaps = 16/208 (7%) Query: 25 NAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQL 84 NA Y L +G+G++G V+KAR+ + G I+A+K++ + D I +E+ +L Sbjct: 5 NANSYTLLRKLGSGSFGVVWKARE-NVSGDIIAIKQIDLETGIDDIT-DIEQEVFMLSNC 62 Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMS 144 + N+++ G L+++ EH++ S L + G L E I + Sbjct: 63 NS---SNVIQYYGCFVDGY--------TLWILMEHMDGGSVSGLLKM-GRLNEQVISIIL 110 Query: 145 HDIISGVDFLHSHRIVHRDLKPHNLLVTVA-GRVKLADFGL-AKTYDVEMKLTSVVVTLW 202 +++ G+++LH +HRD+K N+L++ + G VKLADFG+ A+ + + + V T + Sbjct: 111 REVLYGLNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPF 170 Query: 203 YRPPEVLLGARYCSALDVWSAGCVLAQL 230 + PEV+ Y A D+WS G ++ Sbjct: 171 WMAPEVIQQTSYGLAADIWSLGITAIEM 198 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 80.2 bits (189), Expect = 3e-16 Identities = 59/206 (28%), Positives = 109/206 (52%), Gaps = 18/206 (8%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR---HPN 91 +G GA G+VY A+ + GG+ + + VA+ + T +E+ +L ++ R HPN Sbjct: 315 LGQGASGSVYLAKVV--GGKQLGIFD-SVAIKSIDLQCQTRKEL-ILNEITVMRESIHPN 370 Query: 92 IVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAPGPLPESRIRSMSHDIISG 150 IV LD L R++ L ++V E++ L + ++ L E++I + + G Sbjct: 371 IVTYLD-----SFLVRERHL--WVVMEYMNAGSLTDIIEKSK--LTEAQIARICLETCKG 421 Query: 151 VDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGL-AKTYDVEMKLTSVVVTLWYRPPEVL 209 + LH+ I+HRD+K N+L+ +G +K+ DFG A+ + K ++V T ++ PEV+ Sbjct: 422 IQHLHARNIIHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRVTMVGTPYWMAPEVV 481 Query: 210 LGARYCSALDVWSAGCVLAQLHTRRP 235 Y + +D+WS G ++ ++ P Sbjct: 482 KQNEYGTKVDIWSLGIMIIEMIENEP 507 >SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 79.4 bits (187), Expect = 5e-16 Identities = 70/222 (31%), Positives = 103/222 (46%), Gaps = 23/222 (10%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94 +GTG+ V A+ G + A+K + + G+ EI ++R L RHPNI+R Sbjct: 18 LGTGSTSCVRLAKHAKTG-DLAAIKIIPIRYASIGM------EILMMRLL---RHPNILR 67 Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154 L DV D Q ++L E+V R GPL E I+ V Sbjct: 68 LYDVW-------TDHQH-MYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHC 119 Query: 155 HSHRIVHRDLKPHNLLVTV-AGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGAR 213 H R HRDLK N+L+ V ++K+ADFG+A + L + +L Y PE++ Sbjct: 120 HRFRFRHRDLKLENILIKVNEQQIKIADFGMATVEPNDSCLENYCGSLHYLAPEIVSHKP 179 Query: 214 YCSA-LDVWSAGCVLAQLHTRRPLLP-GASDSDQLHRIFRSG 253 Y A DVWS G +L L + + LP G ++D ++ R G Sbjct: 180 YRGAPADVWSCGVILYSLLSNK--LPFGGQNTDVIYNKIRHG 219 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 79.0 bits (186), Expect = 6e-16 Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 14/213 (6%) Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87 +Y +L LIG G++G+V++A+D+ + +IVA+K V + T+D I T +EI L L + Sbjct: 5 QYRDLQLIGQGSFGSVFRAQDVESS-KIVALKVVDLDATKDQIETLT-QEINFLIDLNSV 62 Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147 +I + G L++ E+ + L + G E I + + Sbjct: 63 ---HITKYYASFVDG--------FRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQV 111 Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLA-KTYDVEMKLTSVVVTLWYRPP 206 + + +LH +HRD+K N+L G VKLADFG++ + + K V T ++ P Sbjct: 112 LEALVYLHGQGKMHRDIKAANILTMKDGLVKLADFGVSGQLESLRDKNDDFVGTPFWMAP 171 Query: 207 EVLLGARYCSALDVWSAGCVLAQLHTRRPLLPG 239 EV+ Y D+WS G +L T P G Sbjct: 172 EVVKQTGYNYKADIWSLGITAYELATGEPPYSG 204 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 78.2 bits (184), Expect = 1e-15 Identities = 72/261 (27%), Positives = 120/261 (45%), Gaps = 24/261 (9%) Query: 1 MSRPSTSQS----PPVVASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIV 56 +S+PS+S P + S S+ ++ ++L+G+G + V++ D Sbjct: 534 VSQPSSSSFTLSFPSALTSSKVSSSTSHLLTRFRNVTLLGSGEFSEVFQVEDPVEKTLKY 593 Query: 57 AMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVRLLDVC-HGGQCLERDQQLVLFL 115 A+KK+KV + ++E+++ R L+ + H IV L+D HGG L++ Sbjct: 594 AVKKLKVKFSGPKERNRLLQEVSIQRALKGHDH--IVELMDSWEHGG---------FLYM 642 Query: 116 VFEHVEQ-DLDSFLSRAP--GPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVT 172 E E LD FL L E R+ + ++ G+ F+H VH DLKP N+++T Sbjct: 643 QVELCENGSLDRFLEEQGQLSRLDEFRVWKILVEVALGLQFIHHKNYVHLDLKPANVMIT 702 Query: 173 VAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHT 232 G +K+ DFG+A + V + Y PEVL Y D++S G + + Sbjct: 703 FEGTLKIGDFGMASVWPVPRGMER-EGDCEYIAPEVLANHLYDKPADIFSLGITVFEA-A 760 Query: 233 RRPLLPGASDSDQLHRIFRSG 253 +LP D+ Q + RSG Sbjct: 761 ANIVLP---DNGQSWQKLRSG 778 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 77.8 bits (183), Expect = 1e-15 Identities = 69/240 (28%), Positives = 111/240 (46%), Gaps = 29/240 (12%) Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLE 85 A +Y + L+G G +G V + D + G+ A+K + L +R + + + Sbjct: 359 ANRYTVVRLLGHGTFGKVIQCYD-QSTGRHCAIKVTRAIPKYREASLIELRVLQTIAHSD 417 Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145 ++L D + + L + VF+ ++ + +++ P P I+ +S Sbjct: 418 PTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNN--NYI-----PFPLKHIQMLSQ 470 Query: 146 DIISGVDFLHSHRIVHRDLKPHN-LLVTVAGR------------------VKLADFGLAK 186 + V FLHS +VH DLKP N LLV+ A R ++L DFG A Sbjct: 471 QLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSA- 529 Query: 187 TYDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246 T++ E +SVV T YR PE++LG + DVWS GC+L +L T + L DS+ L Sbjct: 530 TFEDEYH-SSVVSTRHYRAPEIILGLGWSYPCDVWSIGCILVELFTGQALFQTHEDSEHL 588 >SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosaccharomyces pombe|chr 1|||Manual Length = 696 Score = 76.2 bits (179), Expect = 4e-15 Identities = 58/207 (28%), Positives = 95/207 (45%), Gaps = 12/207 (5%) Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKV-KVALTEDGIPLSTVREIALLRQLE 85 + + L LIG G +G VY R ++ +I AMKK+ K + T+ E +L + Sbjct: 300 EDFTALRLIGKGTFGQVYLVRK-NDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTS 358 Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145 P IV G L+L+ +++ + + G PE R + Sbjct: 359 LDESPFIV--------GLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIA 410 Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK-TYDVEMKLTSVVVTLWYR 204 +++ ++ LH H I++RDLKP N+L+ G + L DFGL+K + T Y Sbjct: 411 ELVLALEHLHKHDIIYRDLKPENILLDADGHIALCDFGLSKANLSANATTNTFCGTTEYL 470 Query: 205 PPEVLLGAR-YCSALDVWSAGCVLAQL 230 PEVLL + Y +D WS G ++ ++ Sbjct: 471 APEVLLEDKGYTKQVDFWSLGVLVFEM 497 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 75.8 bits (178), Expect = 6e-15 Identities = 59/220 (26%), Positives = 112/220 (50%), Gaps = 27/220 (12%) Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIAL-LRQLEA 86 ++++ + +G +G VY ++ G ++A+K++K L + STV +I + LE Sbjct: 1036 RWQQGHFVRSGMFGDVYTGVNMETG-DLLAVKEIK--LQDSRTFRSTVDQIHNEMTVLER 1092 Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH- 145 HPN+V + G + R++ + +F+ F D A G + + + + Sbjct: 1093 LNHPNVVT-----YYGVEVHREK-VYIFMEFCQGGSLADLL---AHGRIEDENVLKVYVV 1143 Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLA-----------KTYDVEMKL 194 ++ G+ ++HS I+HRD+KP N+L+ G +K +DFG A + D++ +L Sbjct: 1144 QLLEGLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPEL 1203 Query: 195 TSVVVTLWYRPPEVLLGARY--CSALDVWSAGCVLAQLHT 232 + T Y PE++LG + A+D+WS GCV+ ++ T Sbjct: 1204 QHLAGTPMYMAPEIILGTKKGDFGAMDIWSLGCVILEMMT 1243 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 74.5 bits (175), Expect = 1e-14 Identities = 54/153 (35%), Positives = 76/153 (49%), Gaps = 13/153 (8%) Query: 76 REIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPL 135 RE+ +LRQL HPNI+ L V + VL L E+++ DL S + + L Sbjct: 70 REVTILRQLH---HPNIITLYQV------FRVPKYTVLAL--EYMDTDLHSMVVKH-NRL 117 Query: 136 PESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLT 195 E R + I+ +D+ H HR+ HRDLK N+L+ VKL DFGL+ L+ Sbjct: 118 DECTTRKIFRQIVHAIDYCHLHRVAHRDLKLENILLNKDLVVKLTDFGLSNFMLDGSFLS 177 Query: 196 SVVVTLWYRPPEVLLGARYCSA-LDVWSAGCVL 227 + T Y PEV+ G Y +DVW G +L Sbjct: 178 TSCGTPHYAAPEVIQGRYYDGCDVDVWGCGILL 210 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 74.5 bits (175), Expect = 1e-14 Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 12/157 (7%) Query: 77 EIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLP 136 E+ LLR +E HPN+++L+DV + +QL + + + + D L + G Sbjct: 58 ELVLLRLIE---HPNVLQLIDV------ISAQEQLFVVVEYMPGGELFDCMLRK--GSFT 106 Query: 137 ESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTS 196 E I+ G+++ H I HRDLKP NL + G +K+ +FG+A L + Sbjct: 107 EQDTAKFLWQILCGLEYCHKLHICHRDLKPENLYLDAHGSIKIGEFGMASIQQPGKLLQT 166 Query: 197 VVVTLWYRPPEVLLGARYCS-ALDVWSAGCVLAQLHT 232 + Y PE+++G Y A D+WS G + L T Sbjct: 167 SCGSPHYASPEIIMGRSYDGCASDIWSCGIIFFALLT 203 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 72.5 bits (170), Expect = 5e-14 Identities = 64/215 (29%), Positives = 105/215 (48%), Gaps = 40/215 (18%) Query: 34 LIGTGAYGTVYKARDLHNGGQ----IVAMKKVKVA-LTEDGIPLSTVREIALLRQLEAYR 88 L+G G + +Y A D + GGQ I+ KK+ ED E+ +LR+L+ Sbjct: 165 LLGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFED-------HEMTILRKLD--- 214 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAPGPLPESRIRSMSHDI 147 HPNI+++ +E + + F+ E V DL S+L++ G +PE + I Sbjct: 215 HPNIIKVN--------MEYNSETQFFIFEEMVTGGDLFSYLTKL-GTVPEVTTLFIMFQI 265 Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAG----RVKLADFGLAKTYDVEMKLTSVVVTLWY 203 + G+ +LH I+HRDLK N+L+ + R+ L DFG+A+ +L++ V T Y Sbjct: 266 LQGLKYLHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFVGTPEY 325 Query: 204 RPPEV--LLG---------ARYCSALDVWSAGCVL 227 PE+ L G + Y +D+WS G ++ Sbjct: 326 TAPEIQRLKGRSQVEKENSSGYGKEVDLWSLGVIM 360 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 72.1 bits (169), Expect = 7e-14 Identities = 68/228 (29%), Positives = 110/228 (48%), Gaps = 27/228 (11%) Query: 12 VVASINDVSALFQNAQ-----KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALT 66 + AS ND+ A N + Y S++G G++G VY A L ++V +K + Sbjct: 9 ISASYNDLIATICNPRISDVGTYRIESVVGEGSFGKVYLAAHLLTNTKVV----LKSSCR 64 Query: 67 EDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLD 125 + I L+ REI R+L HPNI RL +V C E D+ ++L E+ +L Sbjct: 65 KQAIILA--REIHHHRRL---LHPNITRLYEVV----CTE-DR---IYLAMEYCPNGELY 111 Query: 126 SFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLA 185 +++R L E + + + +LH VHRDLK N+ + A VKL DFG + Sbjct: 112 DWVAREKR-LDEKTTCRIMWQLCCAIQYLHRQGCVHRDLKLENIFLDKAYNVKLGDFGFS 170 Query: 186 KTYDVEMK--LTSVVVTLWYRPPEVLLGARYC-SALDVWSAGCVLAQL 230 + D + + + T+ Y PE++ G +Y +D+WS G ++ L Sbjct: 171 RDSDCSRRTFMNTRCGTVAYCAPELVQGHKYIGECVDIWSLGIIMYAL 218 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 71.7 bits (168), Expect = 9e-14 Identities = 76/259 (29%), Positives = 119/259 (45%), Gaps = 29/259 (11%) Query: 3 RPSTSQSPPVVASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVK 62 +PS S+S +D LF+ K+ + +G+GA G+V + + G+I A+K+ + Sbjct: 278 KPSVSKSKSSANLQDDHFGLFKKYGKFGRM--LGSGAGGSV-RIMKRSSDGKIFAVKEFR 334 Query: 63 VALTEDGIPLSTVREIALLRQLE-----AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVF 117 P T RE A E A H NI+ LD+ +E +++ + V Sbjct: 335 ARR-----PTETEREYARKVTAEFCIGSALHHTNIIETLDI------VEENKKF--YEVM 381 Query: 118 EHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRV 177 E+ D+ S + +PE + ++SGV +LHS + HRDLK NL+V V Sbjct: 382 EYAPYDMFSIVMSGKMTMPE--VYCCFKQLLSGVAYLHSMGLAHRDLKLDNLVVDSNCFV 439 Query: 178 KLADFGLAKT--YDVE---MKLTSVVVTLWYRPPEVLLGARY-CSALDVWSAGCVLAQLH 231 K+ DFG A Y E ++ T VV + Y PE L+ Y A+D+WS+ + + Sbjct: 440 KIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAPETLVRKLYDPRAVDIWSSAIIFCCMA 499 Query: 232 TRRPLLPGASDSDQLHRIF 250 RR SD R+F Sbjct: 500 LRRFPWKYPKLSDNSFRLF 518 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 71.3 bits (167), Expect = 1e-13 Identities = 73/239 (30%), Positives = 109/239 (45%), Gaps = 25/239 (10%) Query: 19 VSALFQNAQKYEELS-LIGTGAYGTVYKAR--DLHNGGQ--IVAMKKV--KVALTEDGIP 71 VSA F +KY +IG GA+G V A D N G + A+K+ K A ++ Sbjct: 342 VSASF--VEKYGRCQEVIGRGAFGVVRIAHKVDPQNSGSETLYAVKEFRRKPAESQKKYT 399 Query: 72 LSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRA 131 E + L RHPN++ LD+ G+ D V+ L DL + + A Sbjct: 400 KRLTSEFCISSSL---RHPNVIHTLDLIQDGK---GDYCEVMELCSGG---DLYTLIMAA 450 Query: 132 PGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFG----LAKT 187 G L ++ GVD+LH + HRDLKP NLL+TV+G +K+ DFG Sbjct: 451 -GRLEPMEADCFFKQLMRGVDYLHDMGVAHRDLKPENLLLTVSGSLKITDFGNGECFRMA 509 Query: 188 YDVEMKLT-SVVVTLWYRPPEVLLGARY-CSALDVWSAGCVLAQLHTRRPLLPGASDSD 244 ++ E +T + + Y PE + + A+DVW+ G + + T R L A S+ Sbjct: 510 WEKEAHMTCGLCGSAPYIAPEEYTESEFDPRAVDVWACGVIYMAMRTGRHLWRVAKKSE 568 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 70.5 bits (165), Expect = 2e-13 Identities = 56/205 (27%), Positives = 91/205 (44%), Gaps = 14/205 (6%) Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ-LE 85 Q + L +GTG++G V+ + HN +KV + + + + R L Sbjct: 199 QDFNFLQTLGTGSFGRVHLVQSNHNR----LYYAIKVLEKKKIVDMKQIEHTCDERYILS 254 Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145 +HP I L + L F+V + E L R PE + + Sbjct: 255 RVQHPFITILWGTFQDAKNL--------FMVMDFAEGGELFSLLRKCHRFPEKVAKFYAA 306 Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRP 205 ++I +D+LH ++IV+RDLKP NLL+ G +K+ DFG AK ++ T Y Sbjct: 307 EVILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTS-NCCTLCGTPDYLA 365 Query: 206 PEVLLGARYCSALDVWSAGCVLAQL 230 PE++ Y A D WS G ++ ++ Sbjct: 366 PEIISLKPYNKAADWWSLGILIFEM 390 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 70.5 bits (165), Expect = 2e-13 Identities = 56/159 (35%), Positives = 84/159 (52%), Gaps = 14/159 (8%) Query: 32 LSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPN 91 +S+IG GAYG VYKA D+++G K L E L RE+AL ++ + HP Sbjct: 21 VSIIGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQ-ARELALHARVSS--HPY 77 Query: 92 IVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAPGPLPESR-IRSMSHDIIS 149 I+ L H + LE + +++V ++ DL ++++ S I+++ +IS Sbjct: 78 IITL----H--RVLETED--AIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQLIS 129 Query: 150 GVDFLHSHRIVHRDLKPHNLLV-TVAGRVKLADFGLAKT 187 V+ HS I HRDLKP N++V V LADFGLA T Sbjct: 130 AVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGLATT 168 >SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizosaccharomyces pombe|chr 3|||Manual Length = 569 Score = 70.1 bits (164), Expect = 3e-13 Identities = 60/209 (28%), Positives = 99/209 (47%), Gaps = 14/209 (6%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS-TVREIALLRQLEAY 87 +E L ++G G++G V + R + +I A+K +K A + T+ E +L Q+ Sbjct: 230 FELLKVVGKGSFGKVMQVRK-RDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVN-- 286 Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147 +P IV L + +L L L F + +L L R G R + ++ Sbjct: 287 -NPFIVPLKF------SFQSPGKLYLVLAFVN-GGELFHHLQRE-GCFDTYRAKFYIAEL 337 Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVV-TLWYRPP 206 + ++ LH +++RDLKP N+L+ G + L DFGL K + T+ T Y P Sbjct: 338 LVALECLHEFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAP 397 Query: 207 EVLLGARYCSALDVWSAGCVLAQLHTRRP 235 E+LLG Y +D W+ G +L ++ T P Sbjct: 398 ELLLGHGYTKVVDWWTLGVLLYEMITGLP 426 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 69.7 bits (163), Expect = 4e-13 Identities = 72/239 (30%), Positives = 110/239 (46%), Gaps = 27/239 (11%) Query: 7 SQSPPVVASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALT 66 SQ+ P+ DV + N Q + +L ++G G VY+ N ++ A+K+V Sbjct: 296 SQATPIPKRQQDVVTV-ANLQ-FIKLGVVGKGGSSMVYRIFSPDNS-RLYALKEVNFINA 352 Query: 67 EDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDS 126 + EIALLR+L + I++L + + + QL + V E E DL + Sbjct: 353 DQTTIQGYKNEIALLRKLSG--NDRIIKL----YAAEVNDTLGQLNM--VMECGETDLAN 404 Query: 127 FLSR-APGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLA 185 L + P+ + IR ++ V +H IVH DLKP N L+ V G +KL DFG+A Sbjct: 405 LLMKNMKKPINLNFIRMYWEQMLEAVQVVHDQNIVHSDLKPANFLL-VEGNLKLIDFGIA 463 Query: 186 KTY---DVEMKLTSVVVTLWYRPPEVL--LGARYCSAL---------DVWSAGCVLAQL 230 K + S + T+ Y PE L + A S + DVWS GC+L Q+ Sbjct: 464 KAIGNDTTNIHRDSHIGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQM 522 >SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase Ppk6|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 69.7 bits (163), Expect = 4e-13 Identities = 58/211 (27%), Positives = 99/211 (46%), Gaps = 17/211 (8%) Query: 25 NAQKYEELSLIGTGAYGTV----YKARDLHNGGQIVAMKKVKVALTE--DGIPLSTV-RE 77 N Y + +G GAYG V YK+ +H + ++ K ++ L L TV E Sbjct: 499 NIASYTTIKELGIGAYGQVKLATYKSNKVHEV-ILKSISKSRILLDSWMRDKDLGTVPME 557 Query: 78 IALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPE 137 I++L L+A+ HPNIV+++ E ++ L + DL ++ P + E Sbjct: 558 ISILHFLKAHSHPNIVKMITF------FEDNENYYLLTEPQKPGIDLFDYIELKPS-ISE 610 Query: 138 SRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSV 197 +++ I V LHS I+HRD+K N+++ G +L DFG + + + Sbjct: 611 KESKAIFFQIALAVAHLHSFDIIHRDIKDENVILEGNGCARLIDFG-SSSLTKNGPFDTF 669 Query: 198 VVTLWYRPPEVLLGARYC-SALDVWSAGCVL 227 T+ + PE+L G +Y D+W+ G +L Sbjct: 670 RGTVGFAAPELLRGEKYLGKEQDIWALGILL 700 >SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizosaccharomyces pombe|chr 1|||Manual Length = 646 Score = 69.3 bits (162), Expect = 5e-13 Identities = 63/202 (31%), Positives = 93/202 (46%), Gaps = 12/202 (5%) Query: 32 LSLIGTGAYGTVYKARDLHNGGQIVAMKKV-KVALTEDGIPLSTVREIALLRQLEAYRHP 90 L LIG G +G VY R + ++ AMK + K + TV E +L Q A P Sbjct: 269 LKLIGKGTFGQVYLVRK-KDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSAADSP 327 Query: 91 NIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISG 150 IV L +D L+LV +++ + + PE R + +++ Sbjct: 328 FIVALRFSFQ----TPKD----LYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLA 379 Query: 151 VDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK-TYDVEMKLTSVVVTLWYRPPEVL 209 + LH IV+RDLKP N+L+ V G + L DFGL+K V + T Y PEV+ Sbjct: 380 LQALHKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTFCGTTDYLAPEVI 439 Query: 210 LG-ARYCSALDVWSAGCVLAQL 230 L A Y +D WS G +L ++ Sbjct: 440 LDEAGYDMMVDFWSLGVLLYEM 461 >SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase Cmk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 335 Score = 68.9 bits (161), Expect = 7e-13 Identities = 60/206 (29%), Positives = 91/206 (44%), Gaps = 20/206 (9%) Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVA--MKKVKVALTEDGIPLSTVREIALLRQLE 85 KY ++G G Y TV +A + A M K + +D + EIA+L+++ Sbjct: 30 KYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVK----NEIAILKRV- 84 Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145 +Y HPNI+ L+D E L L + D ++ G E+ ++ Sbjct: 85 SYEHPNILHLVDF------FETVNNLYLITELATGGELFDRICAK--GSFYEADAAALMR 136 Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVA---GRVKLADFGLAKTYDVEM--KLTSVVVT 200 S V +LH + IVHRDLKP NLL + +ADFGL+ Y+ L + T Sbjct: 137 TTTSAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGT 196 Query: 201 LWYRPPEVLLGARYCSALDVWSAGCV 226 Y PEV Y +D+W+ G + Sbjct: 197 PEYMAPEVFRRTGYGKPVDMWAIGVI 222 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 68.5 bits (160), Expect = 9e-13 Identities = 38/111 (34%), Positives = 62/111 (55%), Gaps = 3/111 (2%) Query: 124 LDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSH-RIVHRDLKPHNLLVTVAGRVKLADF 182 LD+ L R GP+P + + + ++ G+ +L++ I+HRDLKP N++V G +KL DF Sbjct: 147 LDAIL-REGGPIPLDILGKIINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDF 205 Query: 183 GLAKTYDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTR 233 G++ V + V T Y PE + G +Y D+WS G + +L T+ Sbjct: 206 GVSGEL-VNSVAQTFVGTSTYMSPERIRGGKYTVKSDIWSLGISIIELATQ 255 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 67.3 bits (157), Expect = 2e-12 Identities = 47/153 (30%), Positives = 78/153 (50%), Gaps = 16/153 (10%) Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147 RHPNI+++LD+ + ++ + + E+V DL +F+++ G + M + Sbjct: 299 RHPNIIKVLDIIY--------KRHTILQIIEYVPYDLFTFITK--GHCSALKADQMFFQL 348 Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTS-----VVVTLW 202 + GV ++HS I HRD+K N+++ VK+ DFG A + + T+ VV + Sbjct: 349 LDGVAYMHSLGIAHRDIKLDNIMLDENLNVKIIDFGTAFVFHYPFESTTLMSDGVVGSKP 408 Query: 203 YRPPEVLLGARY-CSALDVWSAGCVLAQLHTRR 234 Y PEVL Y SA+DVWS V + +R Sbjct: 409 YVAPEVLTQKPYDPSAVDVWSCAIVYCCIALKR 441 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 67.3 bits (157), Expect = 2e-12 Identities = 49/168 (29%), Positives = 76/168 (45%), Gaps = 9/168 (5%) Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148 HPN+V+ D+C ++ DL S + L + M I+ Sbjct: 510 HPNVVKSYDLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLIEDRHDRLGKKDFECMIKQIL 569 Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFG----LAKTYD----VEMKLTSVVVT 200 G++++HS I HRD+KP N+L++ G +++ DFG L D VE K + + Sbjct: 570 RGLNYIHSQGIAHRDIKPENILISEYGVLRITDFGACDVLCNPGDDITAVESKSMGIFGS 629 Query: 201 LWYRPPEVLLGARYCSAL-DVWSAGCVLAQLHTRRPLLPGASDSDQLH 247 Y PE+L Y + D+WS VL L+ R AS +DQL+ Sbjct: 630 DPYMAPEILTPGSYNAFFADMWSTAIVLHCLYFRTYPFRKASQNDQLY 677 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 66.9 bits (156), Expect = 3e-12 Identities = 64/253 (25%), Positives = 111/253 (43%), Gaps = 12/253 (4%) Query: 4 PSTSQSPPVVASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKV 63 P S VVA A + + LS++G G +G V A +L + Q+ A+K +K Sbjct: 658 PVPSVETSVVAQDLTHKAKRIGLEDFTFLSVLGKGNFGKVMLA-ELKSEKQLYAIKVLKK 716 Query: 64 A-LTEDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ 122 + E+ ST E + RHP +V L H C + + ++ + V + V Sbjct: 717 EFILENDEVESTKSEKRVFLVANRERHPFLVNL----HS--CFQTETRI--YFVMDFVSG 768 Query: 123 DLDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADF 182 D L R + + ++ + + H + I++RDLK N+L++ G VK+AD+ Sbjct: 769 G-DLMLHIQQEQFSRRRAQFYAAEVCLALKYFHDNGIIYRDLKLDNILLSPDGHVKVADY 827 Query: 183 GLAKTYDVEMKLTSVVV-TLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGAS 241 GL K T+ T + PE+LL +Y ++D W+ G ++ Q+ + G Sbjct: 828 GLCKEDMWHDNTTATFCGTPEFMAPEILLEQQYTRSVDWWAFGVLIYQMLLGQSPFRGED 887 Query: 242 DSDQLHRIFRSGP 254 + + I P Sbjct: 888 EEEIFDAILSDEP 900 >SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Schizosaccharomyces pombe|chr 3|||Manual Length = 830 Score = 66.9 bits (156), Expect = 3e-12 Identities = 64/257 (24%), Positives = 110/257 (42%), Gaps = 35/257 (13%) Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83 Q Y S IG G++ VYK + +++++K V + + EI++L++ Sbjct: 9 QTIGPYVIRSEIGRGSFAIVYKGKHTETN-RVISIKSVLTKKLTKKLLENLESEISILKE 67 Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQ---LVLFLVFEHVEQDLDSFLSRA--------- 131 + RH ++V L+D G+ + + L F + +S S A Sbjct: 68 I---RHVHVVELIDCIKAGRFIHLVMEYCSLGDLSYFIRKREKFNSIPSLAWINIDHPPV 124 Query: 132 -PGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLV----TVA------------ 174 L E+ +R + + S + FL S ++HRD+KP NLL+ T A Sbjct: 125 YKAGLNETLVRHFTQQLASALQFLRSRSLIHRDVKPQNLLLQPPPTAAYLEEHPQFVGSP 184 Query: 175 --GRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHT 232 +KLADFG A+ ++ + Y PE+L +Y + D+WS G VL ++ Sbjct: 185 KLPMLKLADFGFARYLQTSSMAETLCGSPLYMAPEILRYEKYDAKADLWSVGAVLYEMAV 244 Query: 233 RRPLLPGASDSDQLHRI 249 +P + + L RI Sbjct: 245 GKPPFKAPNHVELLRRI 261 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 66.5 bits (155), Expect = 4e-12 Identities = 58/215 (26%), Positives = 103/215 (47%), Gaps = 25/215 (11%) Query: 25 NAQKYEELSLIGTGAYGTVYKARDLHNG-GQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83 N + +L +G G YG VYKA LH G +A+K+++++L E+ + E+ +L + Sbjct: 316 NMSEIIKLEELGKGNYGVVYKA--LHQPTGVTMALKEIRLSL-EEATFNQIIMELDILHK 372 Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAPGPLPESRIRS 142 + P IV +G +E +F+ E+++ +D A G E + Sbjct: 373 AVS---PYIVDF----YGAFFVEGS----VFICMEYMDAGSMDKLY--AGGIKDEGVLAR 419 Query: 143 MSHDIISGVDFL-HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201 ++ ++ G+ L H I+HRD+KP N+LV G+VKL DFG++ + T++ Sbjct: 420 TAYAVVQGLKTLKEEHNIIHRDVKPTNVLVNSNGQVKLCDFGVSGNLVASISKTNIGCQS 479 Query: 202 WYRPPEVLLGA------RYCSALDVWSAGCVLAQL 230 + P + +G Y DVWS G + ++ Sbjct: 480 YMAPERIRVGGPTNGVLTYTVQADVWSLGLTILEM 514 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 66.5 bits (155), Expect = 4e-12 Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 14/160 (8%) Query: 32 LSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIAL-LRQLEAYRH- 89 L I GAYG VY A+ + G+ A+K + + + L ++ + L R + R+ Sbjct: 531 LKEINRGAYGRVYLAKK-RSSGKYFALKMIPKSSLDS---LKKIKGLLLEKRNMHIQRYG 586 Query: 90 PNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIIS 149 PN V+L G L LV ++ L + GPLPE + + ++++ Sbjct: 587 PNTVKLYYAFDSGD--------YLCLVMDYFNGGDCETLIQKLGPLPEQWVCQYAAELLN 638 Query: 150 GVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYD 189 ++ LH I+H D+KP N+LV G ++L DFGL++ + Sbjct: 639 AIELLHQDGIIHHDIKPANMLVDETGHIRLTDFGLSENVE 678 Score = 27.5 bits (58), Expect = 2.0 Identities = 11/30 (36%), Positives = 18/30 (60%), Gaps = 1/30 (3%) Query: 203 YRPPEVLLGARYCSALDVWSAGCVLAQLHT 232 Y PE+L+G D+W+ GCV+ ++ T Sbjct: 783 YMAPEILMGVDTQMG-DIWAMGCVIFEMLT 811 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 66.1 bits (154), Expect = 5e-12 Identities = 67/256 (26%), Positives = 117/256 (45%), Gaps = 23/256 (8%) Query: 4 PSTSQSPPVVASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQI-VAMKKVK 62 P QS VV + + ++ A Y +IG G++ V +A D + + + + K Sbjct: 30 PVKPQSSNVVPGTSHIGSIKSPAD-YVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKK 88 Query: 63 VALTEDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ 122 + E+ + + +++R L + P I RL H Q L L+ V E Sbjct: 89 YIVKENKVKYVNIERDSMMR-LNGF--PGISRLF---HTFQ-----DDLKLYYVLELAPN 137 Query: 123 -DLDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLAD 181 +L ++ + L E+ +R + +I+S ++++HS I+HRDLKP N+L VK+ D Sbjct: 138 GELLQYIKKYRF-LDENCVRFYAAEILSSIEYMHSCGIIHRDLKPENILFDGNMHVKITD 196 Query: 182 FGLAK--------TYDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTR 233 FG AK + D +S V T Y PE+L + D+W+ CV+ Q+ Sbjct: 197 FGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPELLSRQVVSKSSDLWAFACVVYQMIVG 256 Query: 234 RPLLPGASDSDQLHRI 249 P G++ ++ +I Sbjct: 257 SPPFHGSNPNNIFKKI 272 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 66.1 bits (154), Expect = 5e-12 Identities = 58/220 (26%), Positives = 99/220 (45%), Gaps = 18/220 (8%) Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQL-- 84 +KY+ L IG G++G +YK + L +G ++A K++ E+ +LR L Sbjct: 2 EKYKILECIGHGSFGRIYKVQRLKDGA-LLAQKEIHFGNITRQEKQYIADEVNILRNLKH 60 Query: 85 ---------EAYRHPNIVRL-LDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP 134 E R ++ L ++ C G Q+ EQ++ F ++ Sbjct: 61 PNIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKK-RFTEQEVLKFFTQLLLA 119 Query: 135 LPESRI--RSMSHDIISGVDFLHSHR-IVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE 191 L + + D + H + ++HRD+KP N+ + VKL DFGL+K D Sbjct: 120 LYRCHYGENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLLDNT 179 Query: 192 MKLT-SVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQL 230 T S V T +Y PE++ + Y + DVW+ GCV+ ++ Sbjct: 180 RVFTQSYVGTPYYMSPEIIRSSPYSAKSDVWALGCVIFEI 219 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 65.3 bits (152), Expect = 8e-12 Identities = 60/219 (27%), Positives = 102/219 (46%), Gaps = 30/219 (13%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKV-------KVALTEDGIPLSTVR-EIAL 80 YE + +G G +G V RD +++A+K + K+ VR EIA+ Sbjct: 135 YEIIKELGRGMHGKVKLGRDTVTR-ELLAIKIIPKTERRPKLGRANASSQKEKVRREIAI 193 Query: 81 LRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRI 140 L++ HPN+VRL +V ++ ++LV E++ + L S Sbjct: 194 LKKCV---HPNVVRLREV------IDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEA 244 Query: 141 RSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLA------KTYDVEMKL 194 R D++ G+++LH I+HRD+KP NLL+ + VK++DFG++ D +++L Sbjct: 245 RQYFRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVEL 304 Query: 195 TSVVVTLWYRPPEVLL------GARYCSALDVWSAGCVL 227 V T + PE+ + A+DVW+ G L Sbjct: 305 AKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTL 343 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 64.9 bits (151), Expect = 1e-11 Identities = 49/160 (30%), Positives = 83/160 (51%), Gaps = 10/160 (6%) Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86 Q YE + I G +GTVY +R + G+I A +KV D I + V + R + Sbjct: 562 QDYEIIKPISKGTFGTVYLSRK-NTTGEIYA---IKVLRKVDMISKNQVANVKAERAVLM 617 Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146 + + + + + Q RD L+LV E + + L ++ +PES + + Sbjct: 618 AQEESAF-VAKLYYAFQ--SRDY---LYLVMEFMNGGDCASLLKSLYTIPESWAKIYIAE 671 Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK 186 + G++ LH I+HRD+KP N+L+++ G +KLADFGL++ Sbjct: 672 VALGLEHLHRLGIIHRDIKPDNILMSITGHLKLADFGLSQ 711 Score = 27.1 bits (57), Expect = 2.7 Identities = 11/25 (44%), Positives = 14/25 (56%) Query: 203 YRPPEVLLGARYCSALDVWSAGCVL 227 Y PE L G+ +D W+ GCVL Sbjct: 837 YLAPETLRGSTQDDMVDWWALGCVL 861 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 62.9 bits (146), Expect = 4e-11 Identities = 64/214 (29%), Positives = 101/214 (47%), Gaps = 24/214 (11%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLST-VREIALLRQLEAYRHPNIV 93 + G+YGTV A L + K +K A+ P T ++E+ +LRQL RH NI+ Sbjct: 15 LNKGSYGTVVLAHRLFRTPRC---KDLKYAIKCIKKPAYTFLQEVNILRQLSRSRHRNII 71 Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAPGPLPESR---IRSMSHDIIS 149 ++ + + ++V E+ DL + P +++ I+++ II Sbjct: 72 HFVE--------SFEDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQPEMIKNIFLQIID 123 Query: 150 GVDFLHSHRIVHRDLKPHNLLVTVAGR-----VKLADFGLAKTYDVEMKL-TSVVVTLWY 203 GV LHSH I HRDLKP N L++++ VK++DFGLA + T + Sbjct: 124 GVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLACRDKISYDFGTGSDRYMAP 183 Query: 204 RPPEVLLGARYC-SALDVWSAG-CVLAQLHTRRP 235 E + GA Y A D+W+ G C+L + R P Sbjct: 184 EQFEEVDGAGYSPRAADIWALGICLLNLIFARNP 217 >SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|Schizosaccharomyces pombe|chr 3|||Manual Length = 624 Score = 62.9 bits (146), Expect = 4e-11 Identities = 46/158 (29%), Positives = 85/158 (53%), Gaps = 13/158 (8%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 ++ L +G G YG+V+ A+ N +++AMK +K + + L+ V+ I L + + Sbjct: 162 FDLLVKLGQGGYGSVWLAKK-RNTHELLAMKMMKKSTLQQ---LNEVKHI--LNERDILT 215 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAPGPLPESRIRSMSHDI 147 + N L+ + + Q E+ ++L E+V D +FL+ G L E++ R ++ Sbjct: 216 NTNSEWLVKLYYAFQDKEK-----VYLAMEYVPGGDFRTFLT-TKGLLHENQTRFYLAEM 269 Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLA 185 ++ + +H +HRDLKP N L+ G +KL+DFGL+ Sbjct: 270 VAAISAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLS 307 Score = 37.9 bits (84), Expect = 0.001 Identities = 18/51 (35%), Positives = 27/51 (52%) Query: 191 EMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGAS 241 E K+ SVV + Y PEV+ G +Y +D WS GC+ + P G++ Sbjct: 351 ENKVNSVVGSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVGYPPFSGST 401 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 62.1 bits (144), Expect = 8e-11 Identities = 34/88 (38%), Positives = 51/88 (57%), Gaps = 6/88 (6%) Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK---LTSVVVTLWY 203 ++ G+ F+HS + HRDLKP N+L+ G +K++DFG A + + K L S V + Y Sbjct: 121 LMEGISFMHSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPY 180 Query: 204 RPPEVLLGARY-CSALDVWSAGCVLAQL 230 PE+ +Y S +DVWS G +L L Sbjct: 181 AAPEIT--QQYDGSKVDVWSCGIILFAL 206 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 60.9 bits (141), Expect = 2e-10 Identities = 48/161 (29%), Positives = 79/161 (49%), Gaps = 14/161 (8%) Query: 75 VREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAP- 132 ++E+++L++L+A P +V L++V D +FL ++ E DL FLS Sbjct: 336 LQEVSILQRLQAC--PFVVNLVNVWS-----YNDN---IFLQLDYCENGDLSLFLSELGL 385 Query: 133 -GPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE 191 + R+ M + ++F+H VH D+KP N+L+T G +KL DFGLA + V Sbjct: 386 LQVMDPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGNLKLGDFGLATSLPVS 445 Query: 192 MKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHT 232 + + Y PE+L Y DV+S G + + T Sbjct: 446 -SMVDLEGDRVYIAPEILASHNYGKPADVYSLGLSMIEAAT 485 >SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomyces pombe|chr 1|||Manual Length = 607 Score = 59.7 bits (138), Expect = 4e-10 Identities = 48/175 (27%), Positives = 86/175 (49%), Gaps = 15/175 (8%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 ++ ++ +G G YG+V+ AR + +IVA+K + ++ + +R + R + Sbjct: 208 FQTITQVGQGGYGSVWLARK-RDTKEIVALKIMNKSVLHK---MDEIRHVLTERDILTTA 263 Query: 89 HPN-IVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAPGPLPESRIRSMSHD 146 + +VRLL + Q ++L E V D + LS + G L + + + + Sbjct: 264 NSEWLVRLL---YAFQDTSN-----IYLAMEFVPGGDFRTLLSNS-GVLRDHHAKFYATE 314 Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201 + +D LH +HRDLKP N LV +G +KL DFGL+ + K+ S+ + L Sbjct: 315 MFLAIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSSGIISKKKIESMKIRL 369 Score = 35.5 bits (78), Expect = 0.008 Identities = 17/46 (36%), Positives = 26/46 (56%) Query: 196 SVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGAS 241 SVV + Y PEVL G Y ++D WS GC++ + + P G++ Sbjct: 402 SVVGSPDYMAPEVLRGENYNHSVDYWSLGCIMYECLSGFPPFSGSN 447 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 59.3 bits (137), Expect = 5e-10 Identities = 48/160 (30%), Positives = 86/160 (53%), Gaps = 12/160 (7%) Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREI-ALLRQLEA 86 ++++ LIG+G++GTVY+A +L + G ++A+K +VAL + I ++ I + LE Sbjct: 1119 RWQQGGLIGSGSFGTVYRAVNL-DTGDLMAVK--EVALHKPRISRPMIKRIKGEMLVLEL 1175 Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146 + HPN+ V + G + R++ + + + L FL R E I+ Sbjct: 1176 FDHPNV-----VSYYGIEVHREKVNIFMELCQ--GSSLFEFL-RYGRIEDELVIQVYVLQ 1227 Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK 186 ++ G+ ++HS + H+D+KP N+L G +K DFG AK Sbjct: 1228 LLEGLAYIHSCGVSHQDVKPENILFDHNGIMKFTDFGSAK 1267 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 58.8 bits (136), Expect = 7e-10 Identities = 49/160 (30%), Positives = 77/160 (48%), Gaps = 15/160 (9%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKK----VKVAL-TEDGIPLSTV-REIALLRQLEAYR 88 IGTG +G V L + +K+ L T+ S + RE+A+L+ L Sbjct: 498 IGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNCQTSRLMREVAILKGL-GNN 556 Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148 HP+IV+ LD ++ + L + + + D L+R L +S + +I Sbjct: 557 HPHIVKYLDF------VKTKHHFGIVLDYVNGGELFDYILARRR--LEDSVACRLFAQLI 608 Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY 188 SGV +LHS +VHRDLK N+L+ + +ADFG A T+ Sbjct: 609 SGVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTF 648 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 58.0 bits (134), Expect = 1e-09 Identities = 35/104 (33%), Positives = 52/104 (50%), Gaps = 15/104 (14%) Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK------------TYDVEMKL 194 I+ +D++H ++HRDLKP N+L+ R K+ DFG AK T+ + Sbjct: 207 IVDSIDYMHGRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQ 266 Query: 195 T---SVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRP 235 S V T Y PEVL +A D+W+ GC+L Q+ +P Sbjct: 267 AHSRSFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKP 310 >SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1072 Score = 57.6 bits (133), Expect = 2e-09 Identities = 62/196 (31%), Positives = 102/196 (52%), Gaps = 34/196 (17%) Query: 34 LIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93 +IG G++GT+ R ++ + VA+K+V + + L++ REI LL+Q + HPNIV Sbjct: 659 VIGYGSHGTIVY-RGVYEDRE-VAVKRVLMEFYD----LAS-REITLLQQSD--NHPNIV 709 Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSR--APGPLPES-RIRSMSHDIISG 150 R C ++ Q L++V E + +L + + A L +S + S+ + I G Sbjct: 710 RYY-------CKQKSDQF-LYIVIELCKCNLSDLIEKPIAYDDLFKSIDLVSLLYQIAFG 761 Query: 151 VDFLHSHRIVHRDLKPHNLLVTVAG---------RVKLADFGLAKTYDV---EMKLTS-- 196 V LHS +VHRDLKP N+L+ V R ++DFGL+K D ++ T+ Sbjct: 762 VSHLHSLDLVHRDLKPQNILLVVNNSPNLSKTRVRALISDFGLSKKLDFNQSSLRNTTFE 821 Query: 197 VVVTLWYRPPEVLLGA 212 + +R PE+L G+ Sbjct: 822 AAGSYGWRSPEILSGS 837 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 57.6 bits (133), Expect = 2e-09 Identities = 52/182 (28%), Positives = 84/182 (46%), Gaps = 14/182 (7%) Query: 7 SQSPPVVASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQ--IVAMKKVKVA 64 S SP + + + + + Y+ L I GA+G+VY A+ G I +KK + Sbjct: 567 SPSPRIHTIVPNSAPEHPSINDYKILKPISKGAFGSVYLAQKRTTGDYFAIKILKKSNMI 626 Query: 65 LTEDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDL 124 I + R I L+ Q E+ P + +L +D L+LV E++ Sbjct: 627 AKNQVINVRAERAI-LMSQGES---PFVAKLYYTFQS-----KDY---LYLVMEYLNGGD 674 Query: 125 DSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGL 184 L + G L IR+ + + + LH I+HRD+KP NLL++ G +KL DFGL Sbjct: 675 CGSLLKTMGVLDLDWIRTYIAETVLCLGDLHDRGIIHRDIKPENLLISQNGHLKLTDFGL 734 Query: 185 AK 186 ++ Sbjct: 735 SR 736 Score = 29.1 bits (62), Expect = 0.66 Identities = 13/25 (52%), Positives = 15/25 (60%) Query: 203 YRPPEVLLGARYCSALDVWSAGCVL 227 Y PEV+LG A D WS GCV+ Sbjct: 863 YIAPEVILGNPGIKASDWWSLGCVV 887 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 56.8 bits (131), Expect = 3e-09 Identities = 53/209 (25%), Positives = 96/209 (45%), Gaps = 21/209 (10%) Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82 F++ +++ ++IG G++ TV+ + Q A+K + D + +R LL Sbjct: 24 FESVSQFKIRNVIGKGSWSTVFVVKHRQTK-QRFALKCINKK-KHDEHKIKKLRNEVLL- 80 Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFE-HVEQDLDSFLSRAPGPLPESRIR 141 L++ HP + + E + + ++LV + + DL +S+ ES IR Sbjct: 81 -LQSLNHPLLCKFYS--------EFEDETKIYLVTDLMLGGDLRYHISQRK--FNESVIR 129 Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201 +++S + ++HS ++HRD+KP N+L+ G KLADF +A + +T+ Sbjct: 130 IWMVELVSALIYIHSKGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSNMTV 189 Query: 202 W------YRPPEVLLGARYCSALDVWSAG 224 Y PE L+ A D WS G Sbjct: 190 GRVGTPVYMAPETLIHAVSYKESDWWSLG 218 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 56.8 bits (131), Expect = 3e-09 Identities = 37/93 (39%), Positives = 48/93 (51%), Gaps = 7/93 (7%) Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY----DVE--MKLTSVVVT 200 I+ V +L S RI HRDLKP N+L+ G +KL DFG ++ D E ++ V + Sbjct: 240 ILQAVAYLQSQRIAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRFVSGAVGS 299 Query: 201 LWYRPPEVLLGARYCSAL-DVWSAGCVLAQLHT 232 L Y PE YC L D WS G +L L T Sbjct: 300 LAYLAPEAFHENEYCGLLADRWSCGILLKVLFT 332 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 55.6 bits (128), Expect = 7e-09 Identities = 49/161 (30%), Positives = 79/161 (49%), Gaps = 15/161 (9%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS-TVREIALLRQLEAY 87 +E++ L+G G G VY R+ G+ AMK V ++ I + + R A L Sbjct: 195 FEKVFLLGKGDVGRVYLVRE-KKSGKFYAMK---VLSKQEMIKRNKSKRAFAEQHILATS 250 Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEH-VEQDLDSFLSRAPGP-LPESRIRSMSH 145 HP IV L H Q E L+L E+ + + L R PG L E+ + Sbjct: 251 NHPFIVTLY---HSFQSDE-----YLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIA 302 Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK 186 ++ + +++LH ++RDLKP N+L+ +G + L+DF L+K Sbjct: 303 EVTAALEYLHLMGFIYRDLKPENILLHESGHIMLSDFDLSK 343 Score = 29.1 bits (62), Expect = 0.66 Identities = 14/45 (31%), Positives = 24/45 (53%) Query: 186 KTYDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQL 230 K+ + + S V T Y PEV+ G + SA+D W+ G + ++ Sbjct: 371 KSCIADFRTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEM 415 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 55.2 bits (127), Expect = 9e-09 Identities = 56/227 (24%), Positives = 99/227 (43%), Gaps = 16/227 (7%) Query: 32 LSLIGTGAYGTVYKARDLHNGG--QIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRH 89 L+++G G +G V A N I +KK + E+ L T + + + E +H Sbjct: 667 LAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHVFEVANKE--KH 724 Query: 90 PNIVRLLDVCHGGQCLERDQQLVLFLVFEHV-EQDLDSFLSRAPGPLPESRIRSMSHDII 148 P LL++ Q R ++ V E++ DL + R + R R ++ Sbjct: 725 PF---LLNLFASFQTSTR-----VYFVMEYILGGDLMVHIQRQQFSV--KRARFYGAEVC 774 Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVV-TLWYRPPE 207 + + H + I +RDLK N+L+ G +++AD+GL K + TS T + PE Sbjct: 775 LALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGNTTSTFCGTPEFMAPE 834 Query: 208 VLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRSGP 254 +LL +Y +D W+ G ++ Q+ + G + + I P Sbjct: 835 ILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEP 881 >SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schizosaccharomyces pombe|chr 2|||Manual Length = 526 Score = 52.0 bits (119), Expect = 8e-08 Identities = 49/183 (26%), Positives = 84/183 (45%), Gaps = 15/183 (8%) Query: 19 VSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREI 78 +S + +E++ L+G G G VY R N ++ AMK + + I V + Sbjct: 145 ISRVEVTPHSFEKIRLLGQGDVGKVYLVRQKSNH-RLFAMK---ILNKREMIKRHKVNRV 200 Query: 79 ALLRQ-LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVE--QDLDSFLSRAPGPL 135 ++ L +HP IV L H Q RD L+L E+ + + S L Sbjct: 201 LAEQEILTKSKHPFIVTLY---HSFQ--SRDY---LYLCMEYCAGGEFFRALHSLPKHIL 252 Query: 136 PESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLT 195 PE + ++ + +++LH ++RDLKP N+L+ +G + L+DF L+K + T Sbjct: 253 PEKDACFYAAEVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPT 312 Query: 196 SVV 198 V+ Sbjct: 313 VVL 315 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 50.8 bits (116), Expect = 2e-07 Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 17/113 (15%) Query: 135 LPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLA---KTY--- 188 +P + + I+ + ++HS ++HRDLKP N+ + VKL DFGLA + Y Sbjct: 744 IPVDEMWRLFRQILEALAYIHSRGMMHRDLKPGNIFLDENRNVKLGDFGLATENENYQDN 803 Query: 189 --------DVEMKLTSVVVTLWYRPPEVLL---GARYCSALDVWSAGCVLAQL 230 + LT+ V T Y PE+L G RY + +D++S G +L ++ Sbjct: 804 NDKWKNRQSADEDLTTGVGTALYVAPELLSRRNGVRYDAKVDMYSLGIILFEM 856 Score = 34.3 bits (75), Expect = 0.018 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 5/66 (7%) Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88 +EEL +G G +G V K ++ G+ A+KK+ V L++D +RE+ L +L Sbjct: 556 FEELEFLGRGGFGEVVKVKN-RIDGRFYAVKKL-VLLSDDKENSRILREVMTLSRL---H 610 Query: 89 HPNIVR 94 H ++VR Sbjct: 611 HEHVVR 616 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 50.4 bits (115), Expect = 2e-07 Identities = 33/101 (32%), Positives = 55/101 (54%), Gaps = 6/101 (5%) Query: 147 IISGVDFLHSHRIVHRDLKPHNLLV-TVAGRVKLADFGLA--KTYDVE--MKLTSVVVTL 201 I S +++L H I+HRD+ P+N+L+ ++ G L+DF +A K + E +L + T Sbjct: 113 ISSALEYLEKHGILHRDIHPNNILLDSMNGPAYLSDFSIAWSKQHPGEEVQELIPQIGTG 172 Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGAS 241 YR E L G Y +D W+ G ++A+L + + L S Sbjct: 173 HYRAIETLFGCHSYGHEVDRWTFGILIAELFSNQALFDDGS 213 >SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces pombe|chr 1|||Manual Length = 704 Score = 49.2 bits (112), Expect = 6e-07 Identities = 27/69 (39%), Positives = 40/69 (57%), Gaps = 4/69 (5%) Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLE 85 A +EEL L+G G YG+VYKAR+ +G + A+KK+ + L + RE L +L Sbjct: 221 ASDFEELELLGKGGYGSVYKARNKFDGVE-YALKKIPLRLRSFSTSSNIFRESRTLARL- 278 Query: 86 AYRHPNIVR 94 HPN++R Sbjct: 279 --NHPNVIR 285 Score = 30.7 bits (66), Expect = 0.22 Identities = 13/27 (48%), Positives = 20/27 (74%), Gaps = 1/27 (3%) Query: 147 IISGVDFLH-SHRIVHRDLKPHNLLVT 172 I+ GV +LH + +VHRDLKP N+ ++ Sbjct: 474 ILEGVLYLHDAMHLVHRDLKPRNIFLS 500 >SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Ppk34|Schizosaccharomyces pombe|chr 3|||Manual Length = 354 Score = 48.4 bits (110), Expect = 1e-06 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 3/97 (3%) Query: 134 PLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK 193 P+P R ++ V+++H ++HRD+KP N+L + + DFGLA+ + Sbjct: 171 PMPLETCRKSFRQLVLAVNYIHGKGVIHRDIKPDNILFKENNNLCVIDFGLAEFLPKDGF 230 Query: 194 LTSVVVTLWYRPPEVL---LGARYCSALDVWSAGCVL 227 + T + PE+ L LD+WS G L Sbjct: 231 VKPASGTPAFMAPELFDNELKKIKGKPLDIWSMGVTL 267 >SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosaccharomyces pombe|chr 2|||Manual Length = 365 Score = 47.6 bits (108), Expect = 2e-06 Identities = 21/49 (42%), Positives = 32/49 (65%), Gaps = 3/49 (6%) Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGR---VKLADFGLAKTY 188 ++ +IS ++F+HS +HRD+KP N L+ + R V + DFGLAK Y Sbjct: 110 LADQLISRIEFIHSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKY 158 >SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 580 Score = 46.4 bits (105), Expect = 4e-06 Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 1/53 (1%) Query: 175 GRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVL 227 GR++LADFGL+K + + T+ Y PE++ RY +D+W+ GCVL Sbjct: 302 GRIRLADFGLSKVV-WDSHTQTPCGTMGYTAPEIVRDERYSKGVDMWALGCVL 353 Score = 43.2 bits (97), Expect = 4e-05 Identities = 46/159 (28%), Positives = 77/159 (48%), Gaps = 21/159 (13%) Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHN-GGQIVAMKKVKVAL--TEDGIPLST--VR 76 +++ ++Y L +G GA+ VYKA +HN G+ VA+K V+ A T+ P V Sbjct: 117 VYKGLEQYTLLQKMGDGAFSNVYKA--IHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVE 174 Query: 77 EIALLRQLEAYR---HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVE-QDLDSFLSRAP 132 +L++++ R HPNI++LL+ + +LV E + +L + R Sbjct: 175 SHNILKEVQIMRRVKHPNIIQLLEFIQTPE--------YYYLVLELADGGELFHQIVRLT 226 Query: 133 GPLPESRIRSMSHDIISGVDFLHSH-RIVHRDLKPHNLL 170 E R + + + +LH +VHRD+KP NLL Sbjct: 227 -YFSEDLSRHVITQVAHAIRYLHEDCGVVHRDIKPENLL 264 >SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schizosaccharomyces pombe|chr 1|||Manual Length = 504 Score = 46.0 bits (104), Expect = 5e-06 Identities = 55/232 (23%), Positives = 101/232 (43%), Gaps = 30/232 (12%) Query: 21 ALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIAL 80 A + +KY+ + +G GA+ VYKA + + VA+K ++ +E+ + Sbjct: 57 ANYPGLEKYQLIENLGDGAFSQVYKAYSIDRK-EHVAVKVIRKYEMNKKQRQGVFKEVNI 115 Query: 81 LRQLEAYRHPNIVRLLD----------VCHGGQCLERDQQLVLFLVF-EHVEQDLDSFLS 129 +R++ +H N+V L D V + E Q+V F F E++ + + ++ Sbjct: 116 MRRV---KHKNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVA 172 Query: 130 RAPGPLPE-----SRIRSMSHDIISGVDFLHSHRIVHRDLKPHNL-----LVTVA----G 175 A L + R + + +++L S L+P+ L L + G Sbjct: 173 EAVKHLHDVCGIVHRDIKPENLLFQPIEYLPSQNYTPPSLEPNKLDEGMFLEGIGAGGIG 232 Query: 176 RVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVL 227 R+ +ADFG +K K + T+ Y PE++ Y +D+W+ GCVL Sbjct: 233 RILIADFGFSKVV-WNSKTATPCGTVGYAAPEIVNDELYSKNVDMWAMGCVL 283 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 44.4 bits (100), Expect = 2e-05 Identities = 30/76 (39%), Positives = 45/76 (59%), Gaps = 6/76 (7%) Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTV-AGRVKLADFGLAKTYDVEMKLTSVVVTL 201 ++ +IS ++++HS +HRD+KP N L+ + V + DFGLAK Y + K T V + Sbjct: 111 LADQLISRIEYVHSKSFLHRDIKPDNFLMKKHSNVVTMIDFGLAKKYR-DFK-THVHIP- 167 Query: 202 WYRPPEVLLG-ARYCS 216 YR + L G ARY S Sbjct: 168 -YRDNKNLTGTARYAS 182 >SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 507 Score = 43.2 bits (97), Expect = 4e-05 Identities = 53/198 (26%), Positives = 78/198 (39%), Gaps = 32/198 (16%) Query: 16 INDVSALFQNAQK-YEELSLIGTGAYGTVYKARDLHNGGQI------------VAMKKVK 62 I +++ F Q+ Y + IG G + +VYKA DLH G I + K K Sbjct: 54 IENITRTFVELQENYRLIEKIGEGTFSSVYKAEDLHYGRYINDWDIQSEVLKESSFGKEK 113 Query: 63 VALTEDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCL--------ERDQQLVLF 114 + + ED V + R N + +L + G + DQ LV+ Sbjct: 114 IPVNEDSRKPKYVAIKKIYATSSPARIYNELEILYLLRGSSVIAPLITALRNEDQVLVVL 173 Query: 115 LVFEHVE--QDLDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVT 172 +EH + Q +F R ++M G I+HRD+KP N L Sbjct: 174 PYYEHTDFRQYYSTFSYRDMSIYFRCLFQAMQQTQTLG--------IIHRDIKPSNFLFD 225 Query: 173 VAGR-VKLADFGLAKTYD 189 V + L DFGLA+ YD Sbjct: 226 VRTKHGVLVDFGLAERYD 243 Score = 32.7 bits (71), Expect = 0.053 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 2/52 (3%) Query: 200 TLWYRPPEVLLGARYCSA-LDVWSAGCVLAQLHTRR-PLLPGASDSDQLHRI 249 T +R PEVL S +D+WSAG +L T+R P+ D D L I Sbjct: 291 TRGFRAPEVLFKCSSQSPKVDIWSAGVILLSFLTKRFPMFNSKDDVDALMEI 342 >SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 544 Score = 42.7 bits (96), Expect = 5e-05 Identities = 23/56 (41%), Positives = 32/56 (57%), Gaps = 2/56 (3%) Query: 177 VKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHT 232 VK+AD G A T+ V T YR PEV+LG R+ ++ D WS C++ +L T Sbjct: 356 VKIADLGNACW--TRKHFTNDVQTRQYRSPEVILGCRWGASADCWSFACIIFELLT 409 Score = 39.9 bits (89), Expect = 4e-04 Identities = 37/144 (25%), Positives = 71/144 (49%), Gaps = 11/144 (7%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR--HPNI 92 +G G + TV+ A D + VA+K V+ A + +R + +R+ + +I Sbjct: 87 LGWGHFSTVWLAYD-RAAKRRVALKVVRSAEHYRETSIDEIRILQKIREGDEKHLGKKHI 145 Query: 93 VRLLDV-CHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGPLPESRIRSMSHDIISG 150 + LLD H G + +VFE + ++L S + S +P ++ +++ ++ Sbjct: 146 ISLLDYFVHRGP-----NGAHVCMVFEVLGENLLSLIQSYGHRGVPVGIVKQIAYQLLIA 200 Query: 151 VDFLHSH-RIVHRDLKPHNLLVTV 173 +D+LH I+H DLKP N+L+ + Sbjct: 201 LDYLHRECGIIHTDLKPENVLICI 224 >SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosaccharomyces pombe|chr 1|||Manual Length = 469 Score = 42.7 bits (96), Expect = 5e-05 Identities = 44/161 (27%), Positives = 73/161 (45%), Gaps = 15/161 (9%) Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVR-EIALLRQLE 85 + + + +IG GA+G V + L G +I AMK + L+ V+ E LL + + Sbjct: 91 EDFSTIKVIGKGAFGEVRLVQKLDTG-KIYAMKSLLKTEMFKRDQLAHVKAERDLLVESD 149 Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQ-DLDSFLSRAPGPLPESRIRSMS 144 + P +V L L L+L+ E + DL + L E R Sbjct: 150 S---PWVVSLYYAFQ--------DSLYLYLIMEFLPGGDLMTMLINYD-TFSEDVTRFYM 197 Query: 145 HDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLA 185 + + + +H +HRD+KP N+L+ G +KL+DFGL+ Sbjct: 198 AECVLAIADVHRMGYIHRDIKPDNILIDRDGHIKLSDFGLS 238 >SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizosaccharomyces pombe|chr 2|||Manual Length = 953 Score = 42.3 bits (95), Expect = 7e-05 Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 10/154 (6%) Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVR-EIALLRQLEAYRHPNIV 93 + G + VY A L N V +K++ V D L V EI +++L+ +RH IV Sbjct: 63 LSEGGFSHVYLAL-LENEKPFV-LKRIYVP---DKTALQLVHGEIETMKRLKGHRH--IV 115 Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDF 153 +D E ++ L + F +D +R L E I + D+ V Sbjct: 116 NYIDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNTRLQHRLTEGEILKILADVCDAVAA 175 Query: 154 LH--SHRIVHRDLKPHNLLVTVAGRVKLADFGLA 185 +H ++HRDLK N+L+ KL DFG A Sbjct: 176 MHYLDPPLIHRDLKIENVLLVAPNSYKLCDFGSA 209 >SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosaccharomyces pombe|chr 2|||Manual Length = 429 Score = 41.9 bits (94), Expect = 9e-05 Identities = 43/180 (23%), Positives = 77/180 (42%), Gaps = 21/180 (11%) Query: 27 QKYEELSLIGTGAYGTVYKARDLH---NGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83 + Y + L+G G++ +V+KA D H +++ + D +AL R Sbjct: 38 EDYHVVKLVGAGSFSSVFKAVDRHFDSYDNSYWISSQIEDQMPHDKTKRPKNHFVALKRI 97 Query: 84 LEAYRHPNIVRLLDVCH---GGQCL--------ERDQQLVLFLVFEHVEQDLDSFLSRAP 132 I L++ H G C+ +DQ L++ +H E D ++ + Sbjct: 98 YATVLPSRIQTELEMLHELRGSDCVLNMITAVRHQDQVLIVLPFIQHAEFR-DFYMKYS- 155 Query: 133 GPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVT-VAGRVKLADFGLAKTYDVE 191 LPE I + D++ G+ + + I+HRD+KP N R + DFGLA+ + + Sbjct: 156 --LPE--IGAYLRDLLKGLAHIDAKGIIHRDIKPGNFAWNPYTQRGVILDFGLAQWQEAD 211 Score = 29.5 bits (63), Expect = 0.50 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 200 TLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRR-PLLPGASDSD---QLHRIF-RSG 253 T +R PEVL + S++DVWS G +L T R P D D +L IF R+G Sbjct: 264 TRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPFFRCEDDIDAIVELAHIFGRNG 323 Query: 254 PS 255 S Sbjct: 324 MS 325 >SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces pombe|chr 1|||Manual Length = 639 Score = 41.1 bits (92), Expect = 2e-04 Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 5/68 (7%) Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86 + +EE SL+G G +G+VY R+ +G + AMKK+ + REI L +++ Sbjct: 169 EDFEEYSLLGRGGFGSVYHVRNKIDGAE-YAMKKINSTFQQMSYS-KIFREIKCLAKMD- 225 Query: 87 YRHPNIVR 94 HPN++R Sbjct: 226 --HPNVIR 231 Score = 30.3 bits (65), Expect = 0.29 Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 8/68 (11%) Query: 112 VLFLVFEHVEQDLDSFLSRAPG----PLPESRIR---SMSHDIISGVDFLHSH-RIVHRD 163 ++++ + DL+S+L R PL + +I+ + II+GV ++H ++HRD Sbjct: 358 IIYIQMQLCFDDLESYLIRRNHFLSFPLCKEQIQLHTDLFRMIINGVMYVHEGVNLIHRD 417 Query: 164 LKPHNLLV 171 +KP N+ + Sbjct: 418 IKPSNIFL 425 >SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizosaccharomyces pombe|chr 2|||Manual Length = 872 Score = 40.7 bits (91), Expect = 2e-04 Identities = 55/218 (25%), Positives = 94/218 (43%), Gaps = 28/218 (12%) Query: 35 IGTGAYGTVY--KARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNI 92 I G + VY + +G I A+ K + E+ + EI + L++ +P++ Sbjct: 31 IAEGGFSHVYLVQTNSKTDGSPITAVLKRMYSPDENALRFVKT-EIETMELLKS--NPHV 87 Query: 93 VRLLDVCHGGQCLER---DQQLVLFLVFEHVEQD--LDSFLSRAPGPLPESRIRSMSHDI 147 V +D C LE+ + + L+ E+ +D R L E + + DI Sbjct: 88 VSYIDSCIFP--LEKAGVNTGFEILLLMEYCAGGGLIDFMNQRLQTRLSEHEVLKIISDI 145 Query: 148 ISGVDFLHSHR--IVHRDLKPHNLLVTVAGRVKLADFG--------LAKTYDVEM--KLT 195 + GV LH R ++HRDLK N+L++ KL DFG + +++ K Sbjct: 146 VQGVASLHYLRPPLIHRDLKVENVLLSF-NTFKLCDFGSVTEPMHAAENSSEIQALEKSI 204 Query: 196 SVVVTLWYRPPEVL---LGARYCSALDVWSAGCVLAQL 230 + T YR PE++ G D+W+ G +L +L Sbjct: 205 NTFTTYQYRAPEMINLYSGLGIDEKSDMWALGVLLYKL 242 >SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizosaccharomyces pombe|chr 2|||Manual Length = 413 Score = 39.1 bits (87), Expect = 6e-04 Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 18/108 (16%) Query: 146 DIISGVDFLHSHRIVHRDLK--------PHNLLVTV-------AGRVKLADFGLAKTYDV 190 +++ V +LHS ++HRDLK P+N++ T+ ++++DF L+ D Sbjct: 214 ELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKNYPNALIQISDFELSIFVDS 273 Query: 191 EMKLT-SVVVTLWYRPPEVLLGARYCS-ALDVWSAGCVL-AQLHTRRP 235 + L S + Y PPEV +G + D WS G VL A L R P Sbjct: 274 KNHLVQSSCGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFALLEGRLP 321 >SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 38.7 bits (86), Expect = 8e-04 Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 15/122 (12%) Query: 124 LDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHR--IVHRDLKPHNLLVTVAGRVKLAD 181 +D +R L E I ++ D+ V +H + ++HRDLK N+L+ KL D Sbjct: 125 IDFLNTRLQVRLSEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIENVLLAAPNSYKLCD 184 Query: 182 FGL-------AKTYDVEMKLTSVV--VTLW-YRPPEVL---LGARYCSALDVWSAGCVLA 228 FG AKT +L + T W YR PE++ G D+W+ G + Sbjct: 185 FGSACHPIPGAKTAAEAKQLEYDIEKFTTWQYRCPEMINVHKGFGIDEKSDIWALGVLFY 244 Query: 229 QL 230 +L Sbjct: 245 KL 246 >SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 665 Score = 36.3 bits (80), Expect = 0.004 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%) Query: 137 ESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTS 196 E I S+ ++I SG+ FLH+ I H +L + +T + +K+ ++ + Y +E + Sbjct: 482 ELNIASICYEISSGLAFLHNSGIAHHNLTTECIYLTKSSCLKIGNYAFSSPY-IERQTNR 540 Query: 197 VVVTLWYRPPEVLLGARYCSAL--DVWSAGCVLAQLHTRRP 235 V+ P+ L+ Y DV S G V ++ +P Sbjct: 541 GAVS---HVPDWLIEKNYKEGFMKDVKSLGLVALEIFQGQP 578 >SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizosaccharomyces pombe|chr 2|||Manual Length = 435 Score = 35.9 bits (79), Expect = 0.006 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%) Query: 147 IISGVDFLHSHRIVHRDLKPHNLLV-----TVAGRVKLADFGLAKTY 188 ++S V +H +V+RD+KP N L+ A V + DFG+AK Y Sbjct: 115 MLSRVQTIHEKNLVYRDIKPDNFLIGRPSSRNANMVYMVDFGMAKYY 161 >SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosaccharomyces pombe|chr 1|||Manual Length = 439 Score = 35.1 bits (77), Expect = 0.010 Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 8/72 (11%) Query: 122 QDLDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGR----- 176 +DL + R P + ++ +I+ + +H ++RD+KP N L+ G Sbjct: 96 EDLFDYCGRRFSP---KTVAMIAKQMITRIQSVHERHFIYRDIKPDNFLIGFPGSKTENV 152 Query: 177 VKLADFGLAKTY 188 + DFG+AK Y Sbjct: 153 IYAVDFGMAKQY 164 >SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizosaccharomyces pombe|chr 2|||Manual Length = 1706 Score = 35.1 bits (77), Expect = 0.010 Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 15/131 (11%) Query: 114 FLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTV 173 +LV +V +L +S P L + + + ++ G+ H + H D+K N+L+T Sbjct: 98 YLVRPYVTHNLYDRISTRPF-LELTEKKWIMFQLLKGISDCHRLGVCHGDIKSENILITS 156 Query: 174 AGRVKLADFGLAK-TY-------------DVEMKLTSVVVTLWYRPPEVLLGARYCSALD 219 L+DF K TY D + + + P L A A+D Sbjct: 157 WNWAYLSDFSSFKPTYLPEDNPADYGYFFDTSSRRVCNIAPERFVPASQLQPAPLSPAMD 216 Query: 220 VWSAGCVLAQL 230 ++S GCV A+L Sbjct: 217 IFSLGCVFAEL 227 >SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schizosaccharomyces pombe|chr 2|||Manual Length = 749 Score = 33.9 bits (74), Expect = 0.023 Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 12/119 (10%) Query: 135 LPESRIRSMSHDIISGVDFLH-SHRIVHRDLKPHNLLVTVAGRVKLADFGLAKT------ 187 L E I+ II G+ FLH S +++H +++P +++V G KL F +++ Sbjct: 145 LEEVEIQKGLLQIIDGLVFLHGSAKVIHYNIRPSSVVVDAKGDWKLCGFSFSQSVESARY 204 Query: 188 ----YDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASD 242 YD + +S+ ++ + PE + DV+S GC++ + + + A++ Sbjct: 205 EFNDYDFGIP-SSLQQSMDFLAPEYITHEIAGPESDVFSFGCLIYSIFNKNQSIINANN 262 >SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizosaccharomyces pombe|chr 1|||Manual Length = 344 Score = 33.9 bits (74), Expect = 0.023 Identities = 16/60 (26%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Query: 11 PVVASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGI 70 P ++++ D + N ++Y L+G G + VY +++ N ++ A+KK+K + GI Sbjct: 14 PYISNLFDNDVVCINNERYRIQKLLGEGGFAFVYLVQNVSN-EKLYALKKIKCSFGNKGI 72 Score = 31.5 bits (68), Expect = 0.12 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 14/82 (17%) Query: 160 VHRDLKPHNLLVTVAGR-VKLADFGLAKTYDVEMKLTSVVV----------TLWYRPPE- 207 +H D+KP NLL+ R + L DFG + S + T+ +R PE Sbjct: 191 IHGDIKPDNLLLHENSREIVLTDFGSICLVPIFASNNSEAIAIQDKASENCTMPFRAPEL 250 Query: 208 --VLLGARYCSALDVWSAGCVL 227 V G+ D+WS GC L Sbjct: 251 FHVKAGSTITEKADIWSFGCTL 272 >SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizosaccharomyces pombe|chr 2|||Manual Length = 446 Score = 33.5 bits (73), Expect = 0.031 Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 5/79 (6%) Query: 115 LVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLV--- 171 LV + + L+ L + + +++ V +H +V+RD+KP N L+ Sbjct: 83 LVIDLLGPSLEDLLDLCGRKFSVKTVAMAAKQMLARVQSIHEKSLVYRDIKPDNFLIGRP 142 Query: 172 --TVAGRVKLADFGLAKTY 188 A + + DFG+ K Y Sbjct: 143 NSKNANMIYVVDFGMVKFY 161 >SPAC23A1.19c ||SPAC26H5.01c|RecQ type DNA helicase Hrq1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1063 Score = 29.9 bits (64), Expect = 0.38 Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 7/105 (6%) Query: 70 IPLSTVREIALLRQLE--AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSF 127 + L E+ L L+ AY P +R + G Q Q + E VE+ Sbjct: 688 LTLDLTNEVLLASHLQCAAYELPINIRSDEKFFGNQI-----QDICEANLEMVEESYRPH 742 Query: 128 LSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVT 172 P P + RIRS+S D+ + VD + ++ L+P + +T Sbjct: 743 PKYLPFPASQVRIRSVSEDMFTLVDVTNDKNVILELLEPFRVALT 787 >SPCC1322.12c |bub1||serine/threonine protein kinase Bub1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1044 Score = 29.1 bits (62), Expect = 0.66 Identities = 10/21 (47%), Positives = 16/21 (76%) Query: 151 VDFLHSHRIVHRDLKPHNLLV 171 ++ LH+H+I+H DLK N L+ Sbjct: 849 IEALHTHKIIHGDLKADNALL 869 >SPAC22H10.05c |||mRNA cleavage and polyadenylation specificity factor complex subunit |Schizosaccharomyces pombe|chr 1|||Manual Length = 456 Score = 25.8 bits (54), Expect = 6.1 Identities = 11/31 (35%), Positives = 20/31 (64%) Query: 2 SRPSTSQSPPVVASINDVSALFQNAQKYEEL 32 SR S S+ V + D S++ +NA+KY+++ Sbjct: 218 SRMSQSKDARVSGCLVDTSSIQENAEKYQDI 248 >SPCC417.08 |tef3||translation elongation factor eEF3|Schizosaccharomyces pombe|chr 3|||Manual Length = 1047 Score = 25.8 bits (54), Expect = 6.1 Identities = 19/90 (21%), Positives = 41/90 (45%) Query: 92 IVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGV 151 +++ L VC + + + L F+ EQD S + A + + ++ G+ Sbjct: 17 LLKHLTVCDAAEEADAAKALASFVNGPIEEQDAPSQVFSAISKQLNDKNATARERVLKGL 76 Query: 152 DFLHSHRIVHRDLKPHNLLVTVAGRVKLAD 181 + + +H V D++P+ + + A K+AD Sbjct: 77 EAVANHGSVAADVEPYLVELLPAVIAKVAD 106 >SPCC1739.11c |cdc11||SIN component scaffold protein Cdc11|Schizosaccharomyces pombe|chr 3|||Manual Length = 1045 Score = 25.8 bits (54), Expect = 6.1 Identities = 9/28 (32%), Positives = 18/28 (64%) Query: 135 LPESRIRSMSHDIISGVDFLHSHRIVHR 162 +P R+ +SH+ IS ++ L +++HR Sbjct: 890 MPNLRVLDLSHNYISDIESLKPLQMIHR 917 >SPCC24B10.21 |tpi1|tpi|triosephosphate isomerase|Schizosaccharomyces pombe|chr 3|||Manual Length = 249 Score = 25.4 bits (53), Expect = 8.1 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 4/60 (6%) Query: 12 VVASINDVSALFQNAQK----YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTE 67 VV +N ++ QN K YE + IGTG T +A+++H + A K+ ++ E Sbjct: 143 VVRQLNAIADKVQNWSKIVIAYEPVWAIGTGKTATPEQAQEVHAEIRKWATNKLGASVAE 202 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.322 0.137 0.406 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,134,898 Number of Sequences: 5004 Number of extensions: 44407 Number of successful extensions: 379 Number of sequences better than 10.0: 109 Number of HSP's better than 10.0 without gapping: 106 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 108 Number of HSP's gapped (non-prelim): 146 length of query: 255 length of database: 2,362,478 effective HSP length: 71 effective length of query: 184 effective length of database: 2,007,194 effective search space: 369323696 effective search space used: 369323696 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.9 bits) S2: 53 (25.4 bits)
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