Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001344-TA|BGIBMGA001344-PA|IPR011009|Protein
kinase-like, IPR002290|Serine/threonine protein kinase,
IPR000719|Protein kinase, IPR008271|Serine/threonine protein kinase,
active site
(255 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein ... 272 1e-72
BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase... 272 1e-72
AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase... 272 1e-72
U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein. 252 1e-66
U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4... 252 1e-66
M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein ... 252 1e-66
CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein. 252 1e-66
CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein. 252 1e-66
BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase... 252 1e-66
BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase... 252 1e-66
BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase... 252 1e-66
AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase... 252 1e-66
Z48970-1|CAA88834.1| 303|Homo sapiens orf protein. 248 1e-65
X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein ... 220 3e-57
AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase... 220 3e-57
X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein. 210 5e-54
M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kina... 209 6e-54
BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase... 209 6e-54
BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase... 209 6e-54
AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase... 209 6e-54
X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein. 208 1e-53
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 202 1e-51
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 202 1e-51
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 202 1e-51
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 202 1e-51
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 202 1e-51
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 202 1e-51
X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein ... 200 4e-51
BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase... 200 4e-51
BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase... 200 4e-51
AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase... 200 4e-51
CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein. 197 3e-50
X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein. 196 6e-50
L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kina... 196 6e-50
AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase... 196 6e-50
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 178 2e-44
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 178 2e-44
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 178 2e-44
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 178 2e-44
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 178 2e-44
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 178 2e-44
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 178 2e-44
BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase... 177 2e-44
AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-l... 175 1e-43
AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase p... 175 1e-43
AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase p... 175 1e-43
M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kina... 175 2e-43
U04824-1|AAA19586.1| 779|Homo sapiens PITSLRE alpha 2-1 protein. 174 2e-43
U04818-1|AAA19584.1| 562|Homo sapiens PITSLRE alpha 2-4 protein. 174 2e-43
U04817-1|AAA19583.1| 768|Homo sapiens PITSLRE alpha 2-3 protein. 174 2e-43
U04816-1|AAA19582.1| 777|Homo sapiens PITSLRE alpha 2-2 protein. 174 2e-43
U04815-1|AAA19581.1| 461|Homo sapiens PITSLRE alpha 1 protein. 174 2e-43
M37712-1|AAA36406.1| 439|Homo sapiens p58/GTA protein kinase pr... 174 2e-43
BC139777-1|AAI39778.1| 542|Homo sapiens CDC2L1 protein protein. 174 2e-43
BC062579-1|AAH62579.1| 475|Homo sapiens CDC2L1 protein protein. 174 2e-43
BC033069-1|AAH33069.1| 508|Homo sapiens CDC2L1 protein protein. 174 2e-43
AF080683-5|AAC83666.1| 565|Homo sapiens PITSLRE protein kinase ... 174 2e-43
AF080683-4|AAC83663.1| 738|Homo sapiens PITSLRE protein kinase ... 174 2e-43
AF080683-3|AAC83665.1| 748|Homo sapiens PITSLRE protein kinase ... 174 2e-43
AF080683-2|AAC83662.1| 782|Homo sapiens PITSLRE protein kinase ... 174 2e-43
AF080683-1|AAC83664.1| 755|Homo sapiens PITSLRE protein kinase ... 174 2e-43
AF067517-1|AAC72082.1| 565|Homo sapiens PITSLRE protein kinase ... 174 2e-43
AF067516-1|AAC72081.1| 748|Homo sapiens PITSLRE protein kinase ... 174 2e-43
AF067515-1|AAC72080.1| 795|Homo sapiens PITSLRE protein kinase ... 174 2e-43
AF067514-1|AAC72079.1| 737|Homo sapiens PITSLRE protein kinase ... 174 2e-43
AF067513-1|AAC72078.1| 526|Homo sapiens PITSLRE protein kinase ... 174 2e-43
AF067512-1|AAC72077.1| 782|Homo sapiens PITSLRE protein kinase ... 174 2e-43
BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein. 174 3e-43
AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein. 174 3e-43
AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein. 173 7e-43
U79269-1|AAB50213.1| 229|Homo sapiens cyclin dependent protein ... 172 9e-43
X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein ... 172 1e-42
BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase ... 172 1e-42
BC110905-1|AAI10906.1| 397|Homo sapiens cell division cycle 2-l... 171 2e-42
BC094827-1|AAH94827.1| 475|Homo sapiens CDC2L2 protein protein. 171 2e-42
BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein. 171 2e-42
BC014464-1|AAH14464.1| 464|Homo sapiens CDC2L2 protein protein. 171 2e-42
AL031282-7|CAI20032.1| 783|Homo sapiens cell division cycle 2-l... 171 2e-42
AL031282-6|CAI20034.1| 780|Homo sapiens cell division cycle 2-l... 171 2e-42
AL031282-5|CAI20031.1| 779|Homo sapiens cell division cycle 2-l... 171 2e-42
AL031282-4|CAI20033.1| 770|Homo sapiens cell division cycle 2-l... 171 2e-42
AL031282-3|CAI20030.1| 746|Homo sapiens cell division cycle 2-l... 171 2e-42
AF080694-4|AAC95300.1| 768|Homo sapiens PITSLRE protein kinase ... 171 2e-42
AF080694-3|AAC95298.1| 781|Homo sapiens PITSLRE protein kinase ... 171 2e-42
AF080694-2|AAC95297.1| 777|Homo sapiens PITSLRE protein kinase ... 171 2e-42
AF080694-1|AAC95299.1| 778|Homo sapiens PITSLRE protein kinase ... 171 2e-42
AF067523-1|AAC72088.1| 397|Homo sapiens PITSLRE protein kinase ... 171 2e-42
AF067522-1|AAC72087.1| 780|Homo sapiens PITSLRE protein kinase ... 171 2e-42
AF067521-1|AAC72086.1| 767|Homo sapiens PITSLRE protein kinase ... 171 2e-42
AF067520-1|AAC72085.1| 776|Homo sapiens PITSLRE protein kinase ... 171 2e-42
AF067519-1|AAC72084.1| 777|Homo sapiens PITSLRE protein kinase ... 171 2e-42
AF067518-1|AAC72083.1| 397|Homo sapiens PITSLRE protein kinase ... 171 2e-42
AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein. 171 2e-42
AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein. 171 2e-42
M88563-1|AAB59449.1| 446|Homo sapiens p58 protein kinase protein. 171 2e-42
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 171 2e-42
U07705-1|AAA19595.1| 775|Homo sapiens PITSLRE isoform PBETA22 p... 170 4e-42
U07704-1|AAA19594.1| 777|Homo sapiens PITSLRE isoform PBETA21 p... 170 4e-42
U04819-1|AAA19585.1| 439|Homo sapiens PITSLRE beta 1 protein. 170 4e-42
AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase ... 170 4e-42
AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase ... 170 4e-42
AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase ... 170 4e-42
AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase ... 170 4e-42
BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein k... 169 6e-42
BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase ... 169 6e-42
L25676-1|AAA35668.1| 372|Homo sapiens CDC2-related kinase protein. 169 8e-42
BC001968-1|AAH01968.1| 372|Homo sapiens cyclin-dependent kinase... 169 8e-42
AL162586-9|CAI39768.1| 372|Homo sapiens cyclin-dependent kinase... 169 8e-42
AF517840-1|AAM54039.1| 372|Homo sapiens cyclin-dependent kinase... 169 8e-42
AF174497-1|AAF36538.1| 565|Homo sapiens GR AF-1 coactivator 3 p... 169 1e-41
X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein ... 168 2e-41
BT019903-1|AAV38706.1| 372|Homo sapiens cyclin-dependent kinase... 168 2e-41
AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protei... 168 2e-41
X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein ... 167 3e-41
BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase ... 167 3e-41
BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase ... 167 3e-41
BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein. 167 3e-41
BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein. 167 3e-41
BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase ... 167 3e-41
AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase ... 167 3e-41
X80230-1|CAA56516.1| 372|Homo sapiens serine/threonine protein ... 167 4e-41
AF255306-1|AAF72183.1| 372|Homo sapiens protein kinase CDK9 pro... 167 4e-41
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 166 8e-41
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 166 8e-41
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 166 8e-41
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 164 3e-40
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 164 3e-40
BC025301-1|AAH25301.1| 272|Homo sapiens CDK10 protein protein. 161 2e-39
BC017342-1|AAH17342.1| 283|Homo sapiens CDK10 protein protein. 161 2e-39
AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kina... 161 2e-39
AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kina... 161 2e-39
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 155 1e-37
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 155 1e-37
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 155 1e-37
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 153 4e-37
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 153 4e-37
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 153 4e-37
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 153 4e-37
AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated... 153 8e-37
AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein. 151 2e-36
BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein. 151 2e-36
AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein. 151 2e-36
AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein. 151 2e-36
AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase prot... 151 2e-36
AY065978-1|AAL40897.1| 544|Homo sapiens extracellular signal-re... 151 3e-36
AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase ... 145 1e-34
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 145 2e-34
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 145 2e-34
AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein. 141 2e-33
U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein. 140 4e-33
L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein pr... 140 4e-33
L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein. 140 4e-33
CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein. 140 4e-33
BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated prote... 140 4e-33
BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated prote... 140 4e-33
BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated prote... 140 4e-33
AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protei... 140 4e-33
AB074150-1|BAB85654.1| 307|Homo sapiens Alternative spliced var... 140 4e-33
Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein ... 140 6e-33
U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein. 140 6e-33
L35263-1|AAA57455.1| 360|Homo sapiens CSaids binding protein pr... 140 6e-33
BC039825-1|AAH39825.1| 457|Homo sapiens MAK protein protein. 140 6e-33
BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated prote... 140 6e-33
AL024498-4|CAB75823.1| 623|Homo sapiens protein ( Human DNA seq... 140 6e-33
AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated prot... 140 6e-33
AF505623-1|AAN16405.1| 623|Homo sapiens male germ cell-associat... 140 6e-33
Z84480-1|CAI20520.1| 502|Homo sapiens cell division cycle 2-lik... 138 2e-32
BC037289-1|AAH37289.1| 502|Homo sapiens CDC2L6 protein protein. 138 2e-32
AY028424-1|AAK27731.1| 502|Homo sapiens death-preventing kinase... 138 2e-32
AL603914-4|CAI41175.1| 502|Homo sapiens cell division cycle 2-l... 138 2e-32
AL512430-4|CAI40286.1| 502|Homo sapiens cell division cycle 2-l... 138 2e-32
AK131512-1|BAD18656.1| 345|Homo sapiens protein ( Homo sapiens ... 138 2e-32
AB028951-1|BAA82980.2| 501|Homo sapiens KIAA1028 protein protein. 138 2e-32
X79483-1|CAA55984.1| 367|Homo sapiens extracellular signal regu... 136 5e-32
BC000281-1|AAH00281.2| 283|Homo sapiens PCTK3 protein protein. 136 9e-32
X85753-1|CAA59754.1| 464|Homo sapiens CDK8 protein kinase protein. 134 2e-31
BC107601-1|AAI07602.1| 463|Homo sapiens cyclin-dependent kinase... 134 2e-31
BC105950-1|AAI05951.1| 463|Homo sapiens cyclin-dependent kinase... 134 2e-31
BC104492-1|AAI04493.1| 464|Homo sapiens cyclin-dependent kinase... 134 2e-31
BC069634-1|AAH69634.1| 463|Homo sapiens cyclin-dependent kinase... 134 2e-31
AL590108-1|CAH72300.1| 464|Homo sapiens cyclin-dependent kinase... 134 2e-31
AL159159-1|CAI16960.1| 464|Homo sapiens cyclin-dependent kinase... 134 2e-31
Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein. 134 4e-31
Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase prot... 133 5e-31
M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein. 133 5e-31
BC028034-1|AAH28034.1| 277|Homo sapiens MAPK15 protein protein. 133 5e-31
BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated prote... 133 5e-31
Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase prot... 133 7e-31
M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein. 133 7e-31
DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated prote... 133 7e-31
BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated prote... 133 7e-31
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 132 2e-30
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 132 2e-30
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 132 2e-30
X60188-1|CAA42744.1| 379|Homo sapiens protein serine/threonine ... 131 2e-30
AY033608-1|AAK52330.1| 335|Homo sapiens extracellular signal-re... 131 2e-30
AY033607-1|AAK52329.1| 357|Homo sapiens extracellular signal-re... 131 2e-30
AC006036-1|AAF19245.1| 165|Homo sapiens unknown protein. 131 2e-30
Z95152-3|CAB08438.1| 365|Homo sapiens mitogen-activated protein... 131 3e-30
Y10488-1|CAA71512.1| 365|Homo sapiens stress-activated protein ... 131 3e-30
U93232-1|AAB87639.1| 365|Homo sapiens MAP kinase p38delta protein. 131 3e-30
CR541687-1|CAG46488.1| 365|Homo sapiens MAPK13 protein. 131 3e-30
CR536490-1|CAG38729.1| 365|Homo sapiens MAPK13 protein. 131 3e-30
BT007221-1|AAP35885.1| 365|Homo sapiens mitogen-activated prote... 131 3e-30
BC004428-1|AAH04428.1| 365|Homo sapiens mitogen-activated prote... 131 3e-30
BC001641-1|AAH01641.1| 365|Homo sapiens mitogen-activated prote... 131 3e-30
BC000433-1|AAH00433.1| 365|Homo sapiens mitogen-activated prote... 131 3e-30
AF100546-1|AAF36772.1| 365|Homo sapiens stress-activated protei... 131 3e-30
AF092535-1|AAD23377.1| 365|Homo sapiens mitogen-activated prote... 130 4e-30
U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein. 130 5e-30
U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein. 130 5e-30
U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein. 130 5e-30
U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein. 130 5e-30
BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated prote... 130 5e-30
BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated prote... 130 5e-30
AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated prote... 130 5e-30
BC099905-1|AAH99905.1| 360|Homo sapiens mitogen-activated prote... 129 8e-30
AF015256-1|AAC51758.1| 365|Homo sapiens p38 mitogen-activated p... 129 1e-29
U35003-1|AAC50609.1| 424|Homo sapiens JNK2 beta2 protein kinase... 128 1e-29
U35002-1|AAC50608.1| 382|Homo sapiens JNK2 beta1 protein kinase... 128 1e-29
X80692-1|CAA56709.1| 721|Homo sapiens p97mapk protein. 128 2e-29
L77964-1|AAA98769.1| 721|Homo sapiens ERK3 protein kinase protein. 128 2e-29
BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated prote... 128 2e-29
AF420474-1|AAL17605.1| 721|Homo sapiens ERK-3 protein. 128 2e-29
AF004709-1|AAC51374.1| 365|Homo sapiens stress-activated protei... 128 2e-29
BC024247-1|AAH24247.1| 502|Homo sapiens CDC2L6 protein protein. 128 2e-29
Y14440-1|CAA74792.1| 364|Homo sapiens stress activated protein ... 126 6e-29
U92268-1|AAB66313.1| 364|Homo sapiens mitogen activated protein... 126 6e-29
DQ279722-1|ABB72677.1| 364|Homo sapiens mitogen-activated prote... 126 6e-29
CR456514-1|CAG30400.1| 364|Homo sapiens MAPK11 protein. 126 6e-29
BC027933-1|AAH27933.1| 364|Homo sapiens mitogen-activated prote... 126 6e-29
AL022328-13|CAB51539.1| 364|Homo sapiens mitogen-activated prot... 126 6e-29
AF031135-1|AAC12714.1| 364|Homo sapiens p38beta2 MAP kinase pro... 126 6e-29
AF001174-1|AAC51373.1| 364|Homo sapiens p38beta2 MAP kinase pro... 126 6e-29
AF001008-1|AAC51250.1| 364|Homo sapiens p38Beta2 MAP Kinase pro... 126 6e-29
AK222922-1|BAD96642.1| 307|Homo sapiens MAPK13 protein (Fragmen... 126 8e-29
AC006023-1|AAD54514.1| 727|Homo sapiens WUGSC:H_DJ1147A01.1 pro... 126 1e-28
AL603914-3|CAI41173.1| 251|Homo sapiens cell division cycle 2-l... 124 3e-28
AL603914-2|CAI41172.1| 442|Homo sapiens cell division cycle 2-l... 124 3e-28
AL512430-2|CAI40283.1| 251|Homo sapiens cell division cycle 2-l... 124 3e-28
AL512430-1|CAI40282.1| 442|Homo sapiens cell division cycle 2-l... 124 3e-28
DQ316259-1|ABC40748.1| 516|Homo sapiens nemo like kinase protein. 124 4e-28
BC064663-1|AAH64663.1| 515|Homo sapiens nemo-like kinase protein. 124 4e-28
AF197898-1|AAF04857.1| 515|Homo sapiens nemo-like kinase protein. 124 4e-28
AF180819-1|AAD56013.1| 515|Homo sapiens LAK1 protein protein. 124 4e-28
U53442-1|AAB05036.1| 372|Homo sapiens p38Beta MAP kinase protein. 123 5e-28
U34820-1|AAC50605.1| 422|Homo sapiens JNK3 alpha1 protein kinas... 123 5e-28
U34819-1|AAC50604.1| 464|Homo sapiens JNK3 alpha2 protein kinas... 123 5e-28
U07620-1|AAC50101.1| 422|Homo sapiens MAP kinase protein. 123 5e-28
BC035057-1|AAH35057.1| 464|Homo sapiens MAPK10 protein protein. 123 5e-28
U34821-1|AAC50606.1| 382|Homo sapiens JNK2 alpha1 protein kinas... 122 1e-27
U09759-1|AAA74740.1| 424|Homo sapiens protein kinase protein. 122 1e-27
L31951-1|AAA56831.1| 424|Homo sapiens protein kinase protein. 122 1e-27
DQ066599-1|AAY46156.1| 424|Homo sapiens mitogen-activated prote... 122 1e-27
CR536580-1|CAG38817.1| 424|Homo sapiens MAPK9 protein. 122 1e-27
BC032539-1|AAH32539.1| 424|Homo sapiens mitogen-activated prote... 122 1e-27
L33801-1|AAA66475.1| 420|Homo sapiens protein kinase protein. 122 2e-27
CR536510-1|CAG38748.1| 420|Homo sapiens GSK3B protein. 122 2e-27
BC012760-1|AAH12760.1| 420|Homo sapiens GSK3B protein protein. 122 2e-27
BC000251-1|AAH00251.1| 433|Homo sapiens glycogen synthase kinas... 122 2e-27
Y13493-1|CAA73885.1| 528|Homo sapiens protein kinase Dyrk2 prot... 121 3e-27
U35005-1|AAC50611.1| 427|Homo sapiens JNK1 beta2 protein kinase... 121 3e-27
U35004-1|AAC50610.1| 384|Homo sapiens JNK1 beta1 protein kinase... 121 3e-27
U34822-1|AAC50607.1| 427|Homo sapiens JNK1 alpha2 protein kinas... 121 3e-27
L26318-1|AAA36131.1| 384|Homo sapiens protein kinase protein. 121 3e-27
BC130572-1|AAI30573.1| 427|Homo sapiens mitogen-activated prote... 121 3e-27
BC130570-1|AAI30571.1| 427|Homo sapiens mitogen-activated prote... 121 3e-27
BC006375-1|AAH06375.1| 601|Homo sapiens DYRK2 protein protein. 121 3e-27
BC005809-1|AAH05809.1| 528|Homo sapiens dual-specificity tyrosi... 121 3e-27
CR456515-1|CAG30401.1| 357|Homo sapiens MAPK12 protein. 120 5e-27
L40027-1|AAA62432.1| 483|Homo sapiens glycogen synthase kinase ... 120 7e-27
D63424-1|BAA23608.1| 483|Homo sapiens glycogen synthase kinase ... 120 7e-27
BC051865-1|AAH51865.1| 483|Homo sapiens glycogen synthase kinas... 120 7e-27
BC027984-1|AAH27984.1| 483|Homo sapiens glycogen synthase kinas... 120 7e-27
AC006486-1|AAD11986.1| 483|Homo sapiens KG3A_HUMAN protein. 120 7e-27
BC002655-1|AAH02655.1| 275|Homo sapiens CCRK protein protein. 118 2e-26
AL353572-3|CAH72843.1| 325|Homo sapiens cell cycle related kina... 118 2e-26
X59727-1|CAA42411.1| 557|Homo sapiens 63kDa protein kinase prot... 118 2e-26
BC117216-1|AAI17217.1| 587|Homo sapiens mitogen-activated prote... 118 2e-26
AF113130-1|AAF43778.1| 452|Homo sapiens cyclin-dependent protei... 118 2e-26
AF035013-1|AAC98920.1| 452|Homo sapiens cell cycle related kina... 118 2e-26
BC050299-1|AAH50299.1| 587|Homo sapiens mitogen-activated prote... 118 3e-26
BX537897-1|CAD97888.1| 323|Homo sapiens hypothetical protein pr... 116 6e-26
BC040529-1|AAH40529.1| 231|Homo sapiens PCTK3 protein protein. 116 8e-26
BC034501-1|AAH34501.1| 616|Homo sapiens homeodomain interacting... 113 8e-25
AK057380-1|BAB71458.1| 541|Homo sapiens protein ( Homo sapiens ... 113 8e-25
S67448-1|AAD13991.1| 89|Homo sapiens CDK4 protein. 112 1e-24
AY590695-1|AAT06103.1| 588|Homo sapiens dual-specificity tyrosi... 112 1e-24
AL591846-9|CAI13541.1| 568|Homo sapiens dual-specificity tyrosi... 112 1e-24
AL591846-7|CAI13539.1| 588|Homo sapiens dual-specificity tyrosi... 112 1e-24
AF327561-1|AAK16443.1| 568|Homo sapiens dual-specificity tyrosi... 112 1e-24
AF186774-1|AAG17029.1| 568|Homo sapiens regulatory erythroid ki... 112 1e-24
AF186773-1|AAG17028.1| 588|Homo sapiens regulatory erythroid ki... 112 1e-24
BC053536-1|AAH53536.1| 231|Homo sapiens RAGE protein protein. 111 2e-24
AB022694-1|BAA81688.1| 419|Homo sapiens MOK protein kinase prot... 111 2e-24
AY904367-1|AAW82349.1| 243|Homo sapiens cell cycle-related kina... 110 4e-24
BC015501-1|AAH15501.1| 568|Homo sapiens dual-specificity tyrosi... 110 5e-24
Y12735-1|CAA73266.2| 588|Homo sapiens Dyrk3 protein protein. 109 1e-23
AL353572-5|CAM17658.1| 338|Homo sapiens cell cycle related kina... 109 1e-23
Z95152-2|CAI19690.1| 355|Homo sapiens mitogen-activated protein... 107 4e-23
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 106 9e-23
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 106 9e-23
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 106 9e-23
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 106 9e-23
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 106 9e-23
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 105 2e-22
AB209829-1|BAD93066.1| 214|Homo sapiens cyclin-dependent kinase... 105 2e-22
AF326592-1|AAL37371.1| 1171|Homo sapiens homeodomain interacting... 104 3e-22
AF208291-1|AAG41236.1| 1198|Homo sapiens protein kinase HIPK2 pr... 104 3e-22
BC085196-1|AAH85196.1| 257|Homo sapiens MAPK13 protein protein. 103 6e-22
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 103 8e-22
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 103 8e-22
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 103 8e-22
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 103 8e-22
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 103 8e-22
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 103 8e-22
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 103 8e-22
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 103 8e-22
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 102 1e-21
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 102 1e-21
BX640648-1|CAE45794.1| 319|Homo sapiens hypothetical protein pr... 102 1e-21
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 102 1e-21
BC033012-1|AAH33012.1| 1075|Homo sapiens homeodomain interacting... 102 1e-21
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 102 1e-21
AL731797-3|CAI22793.1| 1210|Homo sapiens homeodomain interacting... 102 1e-21
AL731797-2|CAI22794.1| 1165|Homo sapiens homeodomain interacting... 102 1e-21
AL731797-1|CAI22792.1| 1075|Homo sapiens homeodomain interacting... 102 1e-21
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 102 1e-21
AB089957-1|BAC57075.1| 1210|Homo sapiens homeodomain-interacting... 102 1e-21
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 102 1e-21
AF207702-1|AAG35710.1| 911|Homo sapiens homeodomain-interacting... 101 2e-21
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 101 3e-21
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 101 3e-21
AL122015-2|CAJ55828.1| 1194|Homo sapiens homeodomain interacting... 101 3e-21
AL122015-1|CAC13164.1| 1215|Homo sapiens homeodomain interacting... 101 3e-21
AF305239-1|AAG25990.1| 1194|Homo sapiens Fas-interacting serine/... 101 3e-21
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 101 3e-21
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 101 3e-21
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 101 3e-21
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 101 3e-21
AF004849-1|AAC64294.1| 1215|Homo sapiens PKY protein kinase prot... 101 3e-21
BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein. 100 4e-21
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 100 6e-21
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 100 6e-21
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 100 6e-21
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 100 6e-21
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 100 6e-21
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 100 6e-21
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 100 6e-21
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 100 6e-21
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 100 6e-21
AB209611-1|BAD92848.1| 453|Homo sapiens Mitogen activated prote... 99 8e-21
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 99 1e-20
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 99 1e-20
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 99 1e-20
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 99 1e-20
BC065516-1|AAH65516.1| 319|Homo sapiens MAPK10 protein protein. 99 1e-20
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 99 1e-20
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 99 1e-20
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 99 1e-20
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 99 1e-20
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 99 1e-20
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 99 1e-20
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 99 1e-20
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 99 1e-20
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 99 1e-20
U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein. 99 2e-20
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 98 2e-20
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 98 2e-20
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 98 2e-20
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 98 3e-20
BC051731-1|AAH51731.1| 319|Homo sapiens MAPK10 protein protein. 98 3e-20
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 97 4e-20
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 97 4e-20
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 97 4e-20
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 97 4e-20
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 97 4e-20
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 97 4e-20
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 97 4e-20
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 97 4e-20
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 97 4e-20
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 97 4e-20
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 97 4e-20
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 97 4e-20
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 97 4e-20
BC007992-1|AAH07992.1| 677|Homo sapiens mitogen-activated prote... 97 5e-20
BC007404-1|AAH07404.1| 677|Homo sapiens mitogen-activated prote... 97 5e-20
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 97 7e-20
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 97 7e-20
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 97 7e-20
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 97 7e-20
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 97 7e-20
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 97 7e-20
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 97 7e-20
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 97 7e-20
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 97 7e-20
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 97 7e-20
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 97 7e-20
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 97 7e-20
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 97 7e-20
DQ354583-1|ABC86794.1| 385|Homo sapiens casein kinase 2 alpha i... 96 9e-20
Y17999-3|CAA76990.1| 589|Homo sapiens Dyrk1B protein kinase pro... 96 1e-19
Y17999-2|CAA76989.1| 601|Homo sapiens Dyrk1B protein kinase pro... 96 1e-19
Y17999-1|CAA76991.1| 629|Homo sapiens Dyrk1B protein kinase pro... 96 1e-19
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 96 1e-19
DQ234352-1|ABB29981.1| 308|Homo sapiens mitogen-activated prote... 96 1e-19
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 96 1e-19
BC025291-1|AAH25291.1| 629|Homo sapiens dual-specificity tyrosi... 96 1e-19
BC018751-1|AAH18751.1| 629|Homo sapiens dual-specificity tyrosi... 96 1e-19
AL357131-3|CAH72011.1| 280|Homo sapiens PCTAIRE protein kinase ... 96 1e-19
AF205861-1|AAF15893.1| 629|Homo sapiens protein kinase MIRK pro... 96 1e-19
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 95 2e-19
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 95 2e-19
S53149-1|ABB72474.1| 391|Homo sapiens casein kinase II-alpha su... 95 2e-19
M55265-1|AAA35503.1| 391|Homo sapiens casein kinase II alpha su... 95 2e-19
J02853-1|AAA56821.1| 391|Homo sapiens casein kinase II alpha su... 95 2e-19
BT019792-1|AAV38595.1| 391|Homo sapiens casein kinase 2, alpha ... 95 2e-19
BC071167-1|AAH71167.1| 391|Homo sapiens casein kinase 2, alpha ... 95 2e-19
BC053532-1|AAH53532.1| 391|Homo sapiens casein kinase 2, alpha ... 95 2e-19
BC050036-1|AAH50036.1| 397|Homo sapiens CSNK2A1 protein protein. 95 2e-19
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 95 2e-19
BC011668-1|AAH11668.1| 391|Homo sapiens casein kinase 2, alpha ... 95 2e-19
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 95 2e-19
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 95 2e-19
AL049761-3|CAB65624.1| 391|Homo sapiens casein kinase 2, alpha ... 95 2e-19
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 95 2e-19
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 95 2e-19
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 95 2e-19
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 95 2e-19
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 95 2e-19
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 95 2e-19
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 95 2e-19
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 95 2e-19
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 95 2e-19
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 95 2e-19
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 94 5e-19
AY112721-1|AAM52224.1| 391|Homo sapiens casein kinase II alpha ... 94 5e-19
AL732423-2|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 94 5e-19
AL732423-1|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 94 5e-19
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 94 5e-19
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 94 5e-19
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 94 5e-19
X70251-1|CAA49758.1| 391|Homo sapiens casein kinase II alpha su... 93 7e-19
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 93 7e-19
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 93 7e-19
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 93 7e-19
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 93 7e-19
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 93 7e-19
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 93 7e-19
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 93 7e-19
AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated prote... 93 7e-19
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 93 9e-19
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 93 9e-19
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 93 9e-19
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 93 9e-19
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 93 9e-19
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 93 1e-18
DQ411039-1|ABD66016.1| 260|Homo sapiens protein kinase CDK5 spl... 93 1e-18
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 93 1e-18
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 93 1e-18
AL117326-3|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 93 1e-18
AL117326-2|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 93 1e-18
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 93 1e-18
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 93 1e-18
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 93 1e-18
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 93 1e-18
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 93 1e-18
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 92 2e-18
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 92 2e-18
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 92 2e-18
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 92 2e-18
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 92 2e-18
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 92 2e-18
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 92 2e-18
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 92 2e-18
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 92 2e-18
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 92 2e-18
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 92 2e-18
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 92 2e-18
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 92 2e-18
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 92 2e-18
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 92 2e-18
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 92 2e-18
U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor ... 92 2e-18
BC015669-1|AAH15669.1| 111|Homo sapiens CDK4 protein protein. 92 2e-18
AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein. 92 2e-18
BC108694-1|AAI08695.1| 420|Homo sapiens IKBKB protein protein. 91 3e-18
BC006231-1|AAH06231.1| 256|Homo sapiens IKBKB protein protein. 91 3e-18
AY663108-1|AAT65965.1| 756|Homo sapiens inhibitor of kappa ligh... 91 3e-18
AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens ... 91 3e-18
AF080158-1|AAD08997.1| 756|Homo sapiens IkB kinase-b protein. 91 3e-18
AF029684-1|AAC51860.1| 756|Homo sapiens IkB kinase-beta protein. 91 3e-18
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 91 3e-18
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 91 3e-18
D86968-1|BAA13204.2| 1626|Homo sapiens KIAA0213 protein. 91 3e-18
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 91 3e-18
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 91 3e-18
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 91 3e-18
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 91 3e-18
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 91 3e-18
>X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein
kinase protein.
Length = 326
Score = 272 bits (666), Expect = 1e-72
Identities = 125/224 (55%), Positives = 169/224 (75%), Gaps = 4/224 (1%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+YE ++ IG GAYG V+KARDL NGG+ VA+K+V+V E+G+PLST+RE+A+LR LE
Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSMSH 145
+ HPN+VRL DVC + D++ L LVFEHV+QDL ++L + P P +P I+ M
Sbjct: 71 FEHPNVVRLFDVCTVSRT---DRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMF 127
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRP 205
++ G+DFLHSHR+VHRDLKP N+LVT +G++KLADFGLA+ Y +M LTSVVVTLWYR
Sbjct: 128 QLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRA 187
Query: 206 PEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PEVLL + Y + +D+WS GC+ A++ R+PL G+SD DQL +I
Sbjct: 188 PEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKI 231
>BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 272 bits (666), Expect = 1e-72
Identities = 125/224 (55%), Positives = 169/224 (75%), Gaps = 4/224 (1%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+YE ++ IG GAYG V+KARDL NGG+ VA+K+V+V E+G+PLST+RE+A+LR LE
Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSMSH 145
+ HPN+VRL DVC + D++ L LVFEHV+QDL ++L + P P +P I+ M
Sbjct: 71 FEHPNVVRLFDVCTVSRT---DRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMF 127
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRP 205
++ G+DFLHSHR+VHRDLKP N+LVT +G++KLADFGLA+ Y +M LTSVVVTLWYR
Sbjct: 128 QLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRA 187
Query: 206 PEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PEVLL + Y + +D+WS GC+ A++ R+PL G+SD DQL +I
Sbjct: 188 PEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKI 231
>AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 272 bits (666), Expect = 1e-72
Identities = 125/224 (55%), Positives = 169/224 (75%), Gaps = 4/224 (1%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+YE ++ IG GAYG V+KARDL NGG+ VA+K+V+V E+G+PLST+RE+A+LR LE
Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSMSH 145
+ HPN+VRL DVC + D++ L LVFEHV+QDL ++L + P P +P I+ M
Sbjct: 71 FEHPNVVRLFDVCTVSRT---DRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMF 127
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRP 205
++ G+DFLHSHR+VHRDLKP N+LVT +G++KLADFGLA+ Y +M LTSVVVTLWYR
Sbjct: 128 QLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRA 187
Query: 206 PEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PEVLL + Y + +D+WS GC+ A++ R+PL G+SD DQL +I
Sbjct: 188 PEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKI 231
>U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 252 bits (616), Expect = 1e-66
Identities = 123/227 (54%), Positives = 165/227 (72%), Gaps = 8/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---IPLSTVREIALLRQL 84
+YE ++ IG GAYGTVYKARD H+G VA+K V+V G +P+STVRE+ALLR+L
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSG-HFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSM 143
EA+ HPN+VRL+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ +
Sbjct: 64 EAFEHPNVVRLMDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWY 203
+ G+DFLH++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 204 RPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
R PEVLL + Y + +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 227
>U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 252 bits (616), Expect = 1e-66
Identities = 123/227 (54%), Positives = 165/227 (72%), Gaps = 8/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---IPLSTVREIALLRQL 84
+YE ++ IG GAYGTVYKARD H+G VA+K V+V G +P+STVRE+ALLR+L
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSG-HFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSM 143
EA+ HPN+VRL+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ +
Sbjct: 64 EAFEHPNVVRLMDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWY 203
+ G+DFLH++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 204 RPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
R PEVLL + Y + +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 227
>M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein
kinase, type 4 protein.
Length = 303
Score = 252 bits (616), Expect = 1e-66
Identities = 123/227 (54%), Positives = 165/227 (72%), Gaps = 8/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---IPLSTVREIALLRQL 84
+YE ++ IG GAYGTVYKARD H+G VA+K V+V G +P+STVRE+ALLR+L
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSG-HFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSM 143
EA+ HPN+VRL+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ +
Sbjct: 64 EAFEHPNVVRLMDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWY 203
+ G+DFLH++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 204 RPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
R PEVLL + Y + +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 227
>CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 252 bits (616), Expect = 1e-66
Identities = 123/227 (54%), Positives = 165/227 (72%), Gaps = 8/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---IPLSTVREIALLRQL 84
+YE ++ IG GAYGTVYKARD H+G VA+K V+V G +P+STVRE+ALLR+L
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSG-HFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSM 143
EA+ HPN+VRL+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ +
Sbjct: 64 EAFEHPNVVRLMDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWY 203
+ G+DFLH++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 204 RPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
R PEVLL + Y + +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 227
>CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 252 bits (616), Expect = 1e-66
Identities = 123/227 (54%), Positives = 165/227 (72%), Gaps = 8/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---IPLSTVREIALLRQL 84
+YE ++ IG GAYGTVYKARD H+G VA+K V+V G +P+STVRE+ALLR+L
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSG-HFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSM 143
EA+ HPN+VRL+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ +
Sbjct: 64 EAFEHPNVVRLMDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWY 203
+ G+DFLH++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 204 RPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
R PEVLL + Y + +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 227
>BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 252 bits (616), Expect = 1e-66
Identities = 123/227 (54%), Positives = 165/227 (72%), Gaps = 8/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---IPLSTVREIALLRQL 84
+YE ++ IG GAYGTVYKARD H+G VA+K V+V G +P+STVRE+ALLR+L
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSG-HFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSM 143
EA+ HPN+VRL+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ +
Sbjct: 64 EAFEHPNVVRLMDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWY 203
+ G+DFLH++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 204 RPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
R PEVLL + Y + +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 227
>BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 252 bits (616), Expect = 1e-66
Identities = 123/227 (54%), Positives = 165/227 (72%), Gaps = 8/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---IPLSTVREIALLRQL 84
+YE ++ IG GAYGTVYKARD H+G VA+K V+V G +P+STVRE+ALLR+L
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSG-HFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSM 143
EA+ HPN+VRL+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ +
Sbjct: 64 EAFEHPNVVRLMDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWY 203
+ G+DFLH++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 204 RPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
R PEVLL + Y + +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 227
>BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 252 bits (616), Expect = 1e-66
Identities = 123/227 (54%), Positives = 165/227 (72%), Gaps = 8/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---IPLSTVREIALLRQL 84
+YE ++ IG GAYGTVYKARD H+G VA+K V+V G +P+STVRE+ALLR+L
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSG-HFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSM 143
EA+ HPN+VRL+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ +
Sbjct: 64 EAFEHPNVVRLMDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWY 203
+ G+DFLH++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 204 RPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
R PEVLL + Y + +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 227
>AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 252 bits (616), Expect = 1e-66
Identities = 123/227 (54%), Positives = 165/227 (72%), Gaps = 8/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---IPLSTVREIALLRQL 84
+YE ++ IG GAYGTVYKARD H+G VA+K V+V G +P+STVRE+ALLR+L
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSG-HFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSM 143
EA+ HPN+VRL+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ +
Sbjct: 64 EAFEHPNVVRLMDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWY 203
+ G+DFLH++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 204 RPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
R PEVLL + Y + +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 227
>Z48970-1|CAA88834.1| 303|Homo sapiens orf protein.
Length = 303
Score = 248 bits (608), Expect = 1e-65
Identities = 122/227 (53%), Positives = 164/227 (72%), Gaps = 8/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDG---IPLSTVREIALLRQL 84
+YE ++ IG GAYGTVYKA D H+G VA+K V+V G +P+STVRE+ALLR+L
Sbjct: 5 RYEPVAEIGVGAYGTVYKACDPHSG-HFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 85 EAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSM 143
EA+ HPN+VRL+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ +
Sbjct: 64 EAFEHPNVVRLMDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWY 203
+ G+DFLH++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 204 RPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
R PEVLL + Y + +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 227
>X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein
kinase protein.
Length = 305
Score = 220 bits (538), Expect = 3e-57
Identities = 111/226 (49%), Positives = 156/226 (69%), Gaps = 15/226 (6%)
Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88
++++ IG G YG VYKA++ G Q+VA+KK+++ L +G+P + +REI+LL++L +
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETG-QLVALKKIRLDLEMEGVPSTAIREISLLKEL---K 59
Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSMSHDI 147
HPNIVRLLDV H ER L+LVFE + QDL ++ PG LP I+S +
Sbjct: 60 HPNIVRLLDVVHN----ERK----LYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQL 111
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYRPP 206
+ GV F HSHR++HRDLKP NLL+ G +KLADFGLA+ + V ++ T VVTLWYR P
Sbjct: 112 LQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAP 171
Query: 207 EVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
E+LLG++ Y +A+D+WS GC+ A++ TR+ L PG S+ DQL RIFR
Sbjct: 172 EILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFR 217
>AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase 3
protein.
Length = 305
Score = 220 bits (538), Expect = 3e-57
Identities = 111/226 (49%), Positives = 156/226 (69%), Gaps = 15/226 (6%)
Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88
++++ IG G YG VYKA++ G Q+VA+KK+++ L +G+P + +REI+LL++L +
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETG-QLVALKKIRLDLEMEGVPSTAIREISLLKEL---K 59
Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSMSHDI 147
HPNIVRLLDV H ER L+LVFE + QDL ++ PG LP I+S +
Sbjct: 60 HPNIVRLLDVVHN----ERK----LYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQL 111
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYRPP 206
+ GV F HSHR++HRDLKP NLL+ G +KLADFGLA+ + V ++ T VVTLWYR P
Sbjct: 112 LQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAP 171
Query: 207 EVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
E+LLG++ Y +A+D+WS GC+ A++ TR+ L PG S+ DQL RIFR
Sbjct: 172 EILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFR 217
>X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein.
Length = 298
Score = 210 bits (512), Expect = 5e-54
Identities = 107/229 (46%), Positives = 155/229 (67%), Gaps = 15/229 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ ++++ IG G YG VYKAR+ G ++VA+KK+++ +G+P + +REI+LL++L
Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTG-EVVALKKIRLDTETEGVPSTAIREISLLKELN- 59
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGPLPESRIRSMSH 145
HPNIV+LLDV H + L+LVFE + QDL F+ + A +P I+S
Sbjct: 60 --HPNIVKLLDVIH--------TENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLF 109
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYR 204
++ G+ F HSHR++HRDLKP NLL+ G +KLADFGLA+ + V ++ T VVTLWYR
Sbjct: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYR 169
Query: 205 PPEVLLGARYCS-ALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
PE+LLG++Y S A+D+WS GC+ A++ TRR L PG S+ DQL RIFR+
Sbjct: 170 APEILLGSKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRT 218
>M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kinase
protein.
Length = 298
Score = 209 bits (511), Expect = 6e-54
Identities = 107/229 (46%), Positives = 154/229 (67%), Gaps = 15/229 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ ++++ IG G YG VYKAR+ G ++VA+KK+++ +G+P + +REI+LL++L
Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTG-EVVALKKIRLDTETEGVPSTAIREISLLKELN- 59
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGPLPESRIRSMSH 145
HPNIV+LLDV H + L+LVFE + QDL F+ + A +P I+S
Sbjct: 60 --HPNIVKLLDVIH--------TENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLF 109
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYR 204
++ G+ F HSHR++HRDLKP NLL+ G +KLADFGLA+ + V ++ T VVTLWYR
Sbjct: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYR 169
Query: 205 PPEVLLGARYCS-ALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
PE+LLG +Y S A+D+WS GC+ A++ TRR L PG S+ DQL RIFR+
Sbjct: 170 APEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRT 218
>BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 209 bits (511), Expect = 6e-54
Identities = 107/229 (46%), Positives = 154/229 (67%), Gaps = 15/229 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ ++++ IG G YG VYKAR+ G ++VA+KK+++ +G+P + +REI+LL++L
Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTG-EVVALKKIRLDTETEGVPSTAIREISLLKELN- 59
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGPLPESRIRSMSH 145
HPNIV+LLDV H + L+LVFE + QDL F+ + A +P I+S
Sbjct: 60 --HPNIVKLLDVIH--------TENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLF 109
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYR 204
++ G+ F HSHR++HRDLKP NLL+ G +KLADFGLA+ + V ++ T VVTLWYR
Sbjct: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYR 169
Query: 205 PPEVLLGARYCS-ALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
PE+LLG +Y S A+D+WS GC+ A++ TRR L PG S+ DQL RIFR+
Sbjct: 170 APEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRT 218
>BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 209 bits (511), Expect = 6e-54
Identities = 107/229 (46%), Positives = 154/229 (67%), Gaps = 15/229 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ ++++ IG G YG VYKAR+ G ++VA+KK+++ +G+P + +REI+LL++L
Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTG-EVVALKKIRLDTETEGVPSTAIREISLLKELN- 59
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGPLPESRIRSMSH 145
HPNIV+LLDV H + L+LVFE + QDL F+ + A +P I+S
Sbjct: 60 --HPNIVKLLDVIH--------TENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLF 109
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYR 204
++ G+ F HSHR++HRDLKP NLL+ G +KLADFGLA+ + V ++ T VVTLWYR
Sbjct: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYR 169
Query: 205 PPEVLLGARYCS-ALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
PE+LLG +Y S A+D+WS GC+ A++ TRR L PG S+ DQL RIFR+
Sbjct: 170 APEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRT 218
>AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 209 bits (511), Expect = 6e-54
Identities = 107/229 (46%), Positives = 154/229 (67%), Gaps = 15/229 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ ++++ IG G YG VYKAR+ G ++VA+KK+++ +G+P + +REI+LL++L
Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTG-EVVALKKIRLDTETEGVPSTAIREISLLKELN- 59
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGPLPESRIRSMSH 145
HPNIV+LLDV H + L+LVFE + QDL F+ + A +P I+S
Sbjct: 60 --HPNIVKLLDVIH--------TENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLF 109
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYR 204
++ G+ F HSHR++HRDLKP NLL+ G +KLADFGLA+ + V ++ T VVTLWYR
Sbjct: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYR 169
Query: 205 PPEVLLGARYCS-ALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
PE+LLG +Y S A+D+WS GC+ A++ TRR L PG S+ DQL RIFR+
Sbjct: 170 APEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRT 218
>X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein.
Length = 298
Score = 208 bits (509), Expect = 1e-53
Identities = 107/229 (46%), Positives = 153/229 (66%), Gaps = 15/229 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ ++++ IG G YG VYKAR+ G ++VA+KK++ +G+P + +REI+LL++L
Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTG-EVVALKKIRXDTETEGVPSTAIREISLLKELN- 59
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGPLPESRIRSMSH 145
HPNIV+LLDV H + L+LVFE + QDL F+ + A +P I+S
Sbjct: 60 --HPNIVKLLDVIH--------TENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLF 109
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYR 204
++ G+ F HSHR++HRDLKP NLL+ G +KLADFGLA+ + V ++ T VVTLWYR
Sbjct: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYR 169
Query: 205 PPEVLLGARYCS-ALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
PE+LLG +Y S A+D+WS GC+ A++ TRR L PG S+ DQL RIFR+
Sbjct: 170 APEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRT 218
>Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycle
control gene CDC2. ).
Length = 297
Score = 202 bits (492), Expect = 1e-51
Identities = 108/230 (46%), Positives = 153/230 (66%), Gaps = 16/230 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ Y ++ IG G YG VYK R GQ+VAMKK+++ E+G+P + +REI+LL++L
Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGP-LPESRIRSMS 144
RHPNIV L DV L +D +L +L+FE + DL +L S PG + S ++S
Sbjct: 59 -RHPNIVSLQDV------LMQDSRL--YLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYL 109
Query: 145 HDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWY 203
+ I+ G+ F HS R++HRDLKP NLL+ G +KLADFGLA+ + + +++ T VVTLWY
Sbjct: 110 YQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWY 169
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
R PEVLLG ARY + +D+WS G + A+L T++PL G S+ DQL RIFR+
Sbjct: 170 RSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRA 219
>X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene
involved in cell cycle control. ).
Length = 297
Score = 202 bits (492), Expect = 1e-51
Identities = 108/230 (46%), Positives = 153/230 (66%), Gaps = 16/230 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ Y ++ IG G YG VYK R GQ+VAMKK+++ E+G+P + +REI+LL++L
Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGP-LPESRIRSMS 144
RHPNIV L DV L +D +L +L+FE + DL +L S PG + S ++S
Sbjct: 59 -RHPNIVSLQDV------LMQDSRL--YLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYL 109
Query: 145 HDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWY 203
+ I+ G+ F HS R++HRDLKP NLL+ G +KLADFGLA+ + + +++ T VVTLWY
Sbjct: 110 YQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWY 169
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
R PEVLLG ARY + +D+WS G + A+L T++PL G S+ DQL RIFR+
Sbjct: 170 RSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRA 219
>BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 202 bits (492), Expect = 1e-51
Identities = 108/230 (46%), Positives = 153/230 (66%), Gaps = 16/230 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ Y ++ IG G YG VYK R GQ+VAMKK+++ E+G+P + +REI+LL++L
Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGP-LPESRIRSMS 144
RHPNIV L DV L +D +L +L+FE + DL +L S PG + S ++S
Sbjct: 59 -RHPNIVSLQDV------LMQDSRL--YLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYL 109
Query: 145 HDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWY 203
+ I+ G+ F HS R++HRDLKP NLL+ G +KLADFGLA+ + + +++ T VVTLWY
Sbjct: 110 YQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWY 169
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
R PEVLLG ARY + +D+WS G + A+L T++PL G S+ DQL RIFR+
Sbjct: 170 RSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRA 219
>BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein.
Length = 225
Score = 202 bits (492), Expect = 1e-51
Identities = 108/230 (46%), Positives = 153/230 (66%), Gaps = 16/230 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ Y ++ IG G YG VYK R GQ+VAMKK+++ E+G+P + +REI+LL++L
Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGP-LPESRIRSMS 144
RHPNIV L DV L +D +L +L+FE + DL +L S PG + S ++S
Sbjct: 59 -RHPNIVSLQDV------LMQDSRL--YLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYL 109
Query: 145 HDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWY 203
+ I+ G+ F HS R++HRDLKP NLL+ G +KLADFGLA+ + + +++ T VVTLWY
Sbjct: 110 YQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWY 169
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
R PEVLLG ARY + +D+WS G + A+L T++PL G S+ DQL RIFR+
Sbjct: 170 RSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRN 219
>BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 202 bits (492), Expect = 1e-51
Identities = 108/230 (46%), Positives = 153/230 (66%), Gaps = 16/230 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ Y ++ IG G YG VYK R GQ+VAMKK+++ E+G+P + +REI+LL++L
Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGP-LPESRIRSMS 144
RHPNIV L DV L +D +L +L+FE + DL +L S PG + S ++S
Sbjct: 59 -RHPNIVSLQDV------LMQDSRL--YLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYL 109
Query: 145 HDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWY 203
+ I+ G+ F HS R++HRDLKP NLL+ G +KLADFGLA+ + + +++ T VVTLWY
Sbjct: 110 YQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWY 169
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
R PEVLLG ARY + +D+WS G + A+L T++PL G S+ DQL RIFR+
Sbjct: 170 RSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRA 219
>AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 202 bits (492), Expect = 1e-51
Identities = 108/230 (46%), Positives = 153/230 (66%), Gaps = 16/230 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ Y ++ IG G YG VYK R GQ+VAMKK+++ E+G+P + +REI+LL++L
Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGP-LPESRIRSMS 144
RHPNIV L DV L +D +L +L+FE + DL +L S PG + S ++S
Sbjct: 59 -RHPNIVSLQDV------LMQDSRL--YLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYL 109
Query: 145 HDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWY 203
+ I+ G+ F HS R++HRDLKP NLL+ G +KLADFGLA+ + + +++ T VVTLWY
Sbjct: 110 YQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWY 169
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
R PEVLLG ARY + +D+WS G + A+L T++PL G S+ DQL RIFR+
Sbjct: 170 RSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRA 219
>X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein
kinase protein.
Length = 292
Score = 200 bits (488), Expect = 4e-51
Identities = 106/228 (46%), Positives = 149/228 (65%), Gaps = 15/228 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
QKYE+L IG G YGTV+KA++ +IVA+K+V++ ++G+P S +REI LL++L
Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETH-EIVALKRVRLDDDDEGVPSSALREICLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H NIVRL DV H D++L L VFE +QDL + G L ++S
Sbjct: 59 -KHKNIVRLHDVLHS------DKKLTL--VFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQ 109
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSV-VVTLWYRP 205
++ G+ F HS ++HRDLKP NLL+ G +KLADFGLA+ + + ++ S VVTLWYRP
Sbjct: 110 LLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRP 169
Query: 206 PEVLLGAR-YCSALDVWSAGCVLAQL-HTRRPLLPGASDSDQLHRIFR 251
P+VL GA+ Y +++D+WSAGC+ A+L + RPL PG DQL RIFR
Sbjct: 170 PDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
>BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 200 bits (488), Expect = 4e-51
Identities = 106/228 (46%), Positives = 149/228 (65%), Gaps = 15/228 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
QKYE+L IG G YGTV+KA++ +IVA+K+V++ ++G+P S +REI LL++L
Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETH-EIVALKRVRLDDDDEGVPSSALREICLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H NIVRL DV H D++L L VFE +QDL + G L ++S
Sbjct: 59 -KHKNIVRLHDVLHS------DKKLTL--VFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQ 109
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSV-VVTLWYRP 205
++ G+ F HS ++HRDLKP NLL+ G +KLADFGLA+ + + ++ S VVTLWYRP
Sbjct: 110 LLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRP 169
Query: 206 PEVLLGAR-YCSALDVWSAGCVLAQL-HTRRPLLPGASDSDQLHRIFR 251
P+VL GA+ Y +++D+WSAGC+ A+L + RPL PG DQL RIFR
Sbjct: 170 PDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
>BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 200 bits (488), Expect = 4e-51
Identities = 106/228 (46%), Positives = 149/228 (65%), Gaps = 15/228 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
QKYE+L IG G YGTV+KA++ +IVA+K+V++ ++G+P S +REI LL++L
Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETH-EIVALKRVRLDDDDEGVPSSALREICLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H NIVRL DV H D++L L VFE +QDL + G L ++S
Sbjct: 59 -KHKNIVRLHDVLHS------DKKLTL--VFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQ 109
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSV-VVTLWYRP 205
++ G+ F HS ++HRDLKP NLL+ G +KLADFGLA+ + + ++ S VVTLWYRP
Sbjct: 110 LLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRP 169
Query: 206 PEVLLGAR-YCSALDVWSAGCVLAQL-HTRRPLLPGASDSDQLHRIFR 251
P+VL GA+ Y +++D+WSAGC+ A+L + RPL PG DQL RIFR
Sbjct: 170 PDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
>AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 200 bits (488), Expect = 4e-51
Identities = 106/228 (46%), Positives = 149/228 (65%), Gaps = 15/228 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
QKYE+L IG G YGTV+KA++ +IVA+K+V++ ++G+P S +REI LL++L
Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETH-EIVALKRVRLDDDDEGVPSSALREICLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H NIVRL DV H D++L L VFE +QDL + G L ++S
Sbjct: 59 -KHKNIVRLHDVLHS------DKKLTL--VFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQ 109
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSV-VVTLWYRP 205
++ G+ F HS ++HRDLKP NLL+ G +KLADFGLA+ + + ++ S VVTLWYRP
Sbjct: 110 LLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRP 169
Query: 206 PEVLLGAR-YCSALDVWSAGCVLAQL-HTRRPLLPGASDSDQLHRIFR 251
P+VL GA+ Y +++D+WSAGC+ A+L + RPL PG DQL RIFR
Sbjct: 170 PDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
>CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein.
Length = 292
Score = 197 bits (481), Expect = 3e-50
Identities = 105/228 (46%), Positives = 148/228 (64%), Gaps = 15/228 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
QKYE+L IG G YGTV+KA++ +IVA+K+V++ ++G+P S +REI LL++L
Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETH-EIVALKRVRLDDDDEGVPSSALREICLLKEL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H NIVRL DV H D++L L VFE +QDL + G L ++S
Sbjct: 59 -KHKNIVRLHDVLHS------DKKLTL--VFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQ 109
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSV-VVTLWYRP 205
++ G+ F HS ++HRDLKP N L+ G +KLADFGLA+ + + ++ S VVTLWYRP
Sbjct: 110 LLKGLGFCHSRNVLHRDLKPQNPLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRP 169
Query: 206 PEVLLGAR-YCSALDVWSAGCVLAQL-HTRRPLLPGASDSDQLHRIFR 251
P+VL GA+ Y +++D+WSAGC+ A+L + RPL PG DQL RIFR
Sbjct: 170 PDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
>X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein.
Length = 360
Score = 196 bits (478), Expect = 6e-50
Identities = 106/228 (46%), Positives = 151/228 (66%), Gaps = 12/228 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ +++E+L+ IG G YG VY+ARD +IVA+KKV++ +DGIP+S++REI LL +
Sbjct: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTD-EIVALKKVRMDKEKDGIPISSLREITLLLR 92
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L RHPNIV L +V G LE +FLV + EQDL S L P P E++++ +
Sbjct: 93 L---RHPNIVELKEVVVGNH-LES-----IFLVMGYCEQDLASLLENMPTPFSEAQVKCI 143
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ G+ +LH + I+HRDLK NLL+T G VK ADFGLA+ Y V +K +T VVTLW
Sbjct: 144 VLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLW 203
Query: 203 YRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
YR PE+LLG +++D+W+ GC+LA+L RPLLPG S+ Q+ I
Sbjct: 204 YRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 251
>L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kinase
protein.
Length = 314
Score = 196 bits (478), Expect = 6e-50
Identities = 106/228 (46%), Positives = 151/228 (66%), Gaps = 12/228 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ +++E+L+ IG G YG VY+ARD +IVA+KKV++ +DGIP+S++REI LL +
Sbjct: 5 RSVKEFEKLNRIGEGTYGIVYRARDTQTD-EIVALKKVRMDKEKDGIPISSLREITLLLR 63
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L RHPNIV L +V G LE +FLV + EQDL S L P P E++++ +
Sbjct: 64 L---RHPNIVELKEVVVGNH-LES-----IFLVMGYCEQDLASLLENMPTPFSEAQVKCI 114
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ G+ +LH + I+HRDLK NLL+T G VK ADFGLA+ Y V +K +T VVTLW
Sbjct: 115 VLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLW 174
Query: 203 YRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
YR PE+LLG +++D+W+ GC+LA+L RPLLPG S+ Q+ I
Sbjct: 175 YRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 222
>AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase
protein.
Length = 360
Score = 196 bits (478), Expect = 6e-50
Identities = 106/228 (46%), Positives = 151/228 (66%), Gaps = 12/228 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ +++E+L+ IG G YG VY+ARD +IVA+KKV++ +DGIP+S++REI LL +
Sbjct: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTD-EIVALKKVRMDKEKDGIPISSLREITLLLR 92
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L RHPNIV L +V G LE +FLV + EQDL S L P P E++++ +
Sbjct: 93 L---RHPNIVELKEVVVGNH-LES-----IFLVMGYCEQDLASLLENMPTPFSEAQVKCI 143
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ G+ +LH + I+HRDLK NLL+T G VK ADFGLA+ Y V +K +T VVTLW
Sbjct: 144 VLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLW 203
Query: 203 YRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
YR PE+LLG +++D+W+ GC+LA+L RPLLPG S+ Q+ I
Sbjct: 204 YRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 251
>Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein
kinase protein.
Length = 346
Score = 178 bits (433), Expect = 2e-44
Identities = 104/232 (44%), Positives = 144/232 (62%), Gaps = 17/232 (7%)
Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKV---ALTEDGIPLSTVREIALLR 82
A++YE+L +G G + TVYKARD N QIVA+KK+K+ + +DGI + +REI LL+
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARD-KNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+L HPNI+ LLD + + LVF+ +E DL+ + L S I++
Sbjct: 68 ELS---HPNIIGLLDAF--------GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKA 116
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DVEMKLTSVVVTL 201
+ G+++LH H I+HRDLKP+NLL+ G +KLADFGLAK++ T VVT
Sbjct: 117 YMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTR 176
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
WYR PE+L GAR Y +D+W+ GC+LA+L R P LPG SD DQL RIF +
Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFET 228
>X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinase
(CAK) protein.
Length = 346
Score = 178 bits (433), Expect = 2e-44
Identities = 104/232 (44%), Positives = 144/232 (62%), Gaps = 17/232 (7%)
Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKV---ALTEDGIPLSTVREIALLR 82
A++YE+L +G G + TVYKARD N QIVA+KK+K+ + +DGI + +REI LL+
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARD-KNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+L HPNI+ LLD + + LVF+ +E DL+ + L S I++
Sbjct: 68 ELS---HPNIIGLLDAF--------GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKA 116
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DVEMKLTSVVVTL 201
+ G+++LH H I+HRDLKP+NLL+ G +KLADFGLAK++ T VVT
Sbjct: 117 YMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTR 176
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
WYR PE+L GAR Y +D+W+ GC+LA+L R P LPG SD DQL RIF +
Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFET 228
>X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase
protein.
Length = 346
Score = 178 bits (433), Expect = 2e-44
Identities = 104/232 (44%), Positives = 144/232 (62%), Gaps = 17/232 (7%)
Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKV---ALTEDGIPLSTVREIALLR 82
A++YE+L +G G + TVYKARD N QIVA+KK+K+ + +DGI + +REI LL+
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARD-KNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+L HPNI+ LLD + + LVF+ +E DL+ + L S I++
Sbjct: 68 ELS---HPNIIGLLDAF--------GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKA 116
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DVEMKLTSVVVTL 201
+ G+++LH H I+HRDLKP+NLL+ G +KLADFGLAK++ T VVT
Sbjct: 117 YMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTR 176
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
WYR PE+L GAR Y +D+W+ GC+LA+L R P LPG SD DQL RIF +
Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFET 228
>X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase
protein.
Length = 346
Score = 178 bits (433), Expect = 2e-44
Identities = 104/232 (44%), Positives = 144/232 (62%), Gaps = 17/232 (7%)
Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKV---ALTEDGIPLSTVREIALLR 82
A++YE+L +G G + TVYKARD N QIVA+KK+K+ + +DGI + +REI LL+
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARD-KNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+L HPNI+ LLD + + LVF+ +E DL+ + L S I++
Sbjct: 68 ELS---HPNIIGLLDAF--------GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKA 116
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DVEMKLTSVVVTL 201
+ G+++LH H I+HRDLKP+NLL+ G +KLADFGLAK++ T VVT
Sbjct: 117 YMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTR 176
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
WYR PE+L GAR Y +D+W+ GC+LA+L R P LPG SD DQL RIF +
Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFET 228
>L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine
kinase protein.
Length = 346
Score = 178 bits (433), Expect = 2e-44
Identities = 104/232 (44%), Positives = 144/232 (62%), Gaps = 17/232 (7%)
Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKV---ALTEDGIPLSTVREIALLR 82
A++YE+L +G G + TVYKARD N QIVA+KK+K+ + +DGI + +REI LL+
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARD-KNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+L HPNI+ LLD + + LVF+ +E DL+ + L S I++
Sbjct: 68 ELS---HPNIIGLLDAF--------GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKA 116
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DVEMKLTSVVVTL 201
+ G+++LH H I+HRDLKP+NLL+ G +KLADFGLAK++ T VVT
Sbjct: 117 YMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTR 176
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
WYR PE+L GAR Y +D+W+ GC+LA+L R P LPG SD DQL RIF +
Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFET 228
>BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 178 bits (433), Expect = 2e-44
Identities = 104/232 (44%), Positives = 144/232 (62%), Gaps = 17/232 (7%)
Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKV---ALTEDGIPLSTVREIALLR 82
A++YE+L +G G + TVYKARD N QIVA+KK+K+ + +DGI + +REI LL+
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARD-KNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+L HPNI+ LLD + + LVF+ +E DL+ + L S I++
Sbjct: 68 ELS---HPNIIGLLDAF--------GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKA 116
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DVEMKLTSVVVTL 201
+ G+++LH H I+HRDLKP+NLL+ G +KLADFGLAK++ T VVT
Sbjct: 117 YMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTR 176
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
WYR PE+L GAR Y +D+W+ GC+LA+L R P LPG SD DQL RIF +
Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFET 228
>AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase 7
protein.
Length = 346
Score = 178 bits (433), Expect = 2e-44
Identities = 104/232 (44%), Positives = 144/232 (62%), Gaps = 17/232 (7%)
Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKV---ALTEDGIPLSTVREIALLR 82
A++YE+L +G G + TVYKARD N QIVA+KK+K+ + +DGI + +REI LL+
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARD-KNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+L HPNI+ LLD + + LVF+ +E DL+ + L S I++
Sbjct: 68 ELS---HPNIIGLLDAF--------GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKA 116
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DVEMKLTSVVVTL 201
+ G+++LH H I+HRDLKP+NLL+ G +KLADFGLAK++ T VVT
Sbjct: 117 YMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTR 176
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
WYR PE+L GAR Y +D+W+ GC+LA+L R P LPG SD DQL RIF +
Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFET 228
>BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 177 bits (432), Expect = 2e-44
Identities = 104/232 (44%), Positives = 144/232 (62%), Gaps = 17/232 (7%)
Query: 26 AQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKV---ALTEDGIPLSTVREIALLR 82
A++YE+L +G G + TVYKARD N QIVA+KK+K+ + +DGI + +REI LL+
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARD-KNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+L HPNI+ LLD + + LVF+ +E DL+ + L S I++
Sbjct: 68 ELS---HPNIIGLLDAF--------GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKA 116
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DVEMKLTSVVVTL 201
+ G+++LH H I+HRDLKP+NLL+ G +KLADFGLAK++ T VVT
Sbjct: 117 YMLMTLQGLEYLHRHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTR 176
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
WYR PE+L GAR Y +D+W+ GC+LA+L R P LPG SD DQL RIF +
Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFET 228
>AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-like
5 (cholinesterase-related cell division controller)
protein.
Length = 1512
Score = 175 bits (426), Expect = 1e-43
Identities = 90/229 (39%), Positives = 142/229 (62%), Gaps = 9/229 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K++ + +IG G YG VYKARD + G++VA+KKV++ ++G P++ +REI +LRQL
Sbjct: 704 KFDIIGIIGEGTYGQVYKARD-KDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLT-- 760
Query: 88 RHPNIVRLLDVCHGGQ-CLE-RDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145
H +I+ + ++ + L+ + + +LVFE+++ DL L E+ I+S
Sbjct: 761 -HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMR 819
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE--MKLTSVVVTLWY 203
++ G+D+ H +HRD+K N+L+ G++KLADFGLA+ Y E T+ V+TLWY
Sbjct: 820 QLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWY 879
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
RPPE+LLG RY A+DVWS GC+L +L T++P+ + QL I R
Sbjct: 880 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISR 928
>AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase
protein.
Length = 1452
Score = 175 bits (426), Expect = 1e-43
Identities = 90/229 (39%), Positives = 142/229 (62%), Gaps = 9/229 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K++ + +IG G YG VYKARD + G++VA+KKV++ ++G P++ +REI +LRQL
Sbjct: 704 KFDIIGIIGEGTYGQVYKARD-KDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLT-- 760
Query: 88 RHPNIVRLLDVCHGGQ-CLE-RDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145
H +I+ + ++ + L+ + + +LVFE+++ DL L E+ I+S
Sbjct: 761 -HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMR 819
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE--MKLTSVVVTLWY 203
++ G+D+ H +HRD+K N+L+ G++KLADFGLA+ Y E T+ V+TLWY
Sbjct: 820 QLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWY 879
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
RPPE+LLG RY A+DVWS GC+L +L T++P+ + QL I R
Sbjct: 880 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISR 928
>AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase
protein.
Length = 1512
Score = 175 bits (426), Expect = 1e-43
Identities = 90/229 (39%), Positives = 142/229 (62%), Gaps = 9/229 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K++ + +IG G YG VYKARD + G++VA+KKV++ ++G P++ +REI +LRQL
Sbjct: 704 KFDIIGIIGEGTYGQVYKARD-KDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLT-- 760
Query: 88 RHPNIVRLLDVCHGGQ-CLE-RDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145
H +I+ + ++ + L+ + + +LVFE+++ DL L E+ I+S
Sbjct: 761 -HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMR 819
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE--MKLTSVVVTLWY 203
++ G+D+ H +HRD+K N+L+ G++KLADFGLA+ Y E T+ V+TLWY
Sbjct: 820 QLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWY 879
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
RPPE+LLG RY A+DVWS GC+L +L T++P+ + QL I R
Sbjct: 880 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISR 928
>M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kinase
protein.
Length = 418
Score = 175 bits (425), Expect = 2e-43
Identities = 90/229 (39%), Positives = 142/229 (62%), Gaps = 9/229 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K++ + +IG G YG VYKARD + G++VA+KKV++ ++G P++ +REI +LRQL
Sbjct: 90 KFDIIGIIGEGTYGQVYKARD-KDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLT-- 146
Query: 88 RHPNIVRLLDVCHGGQ-CLE-RDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145
H +I+ + ++ + L+ + + +LVFE+++ DL L E+ I+S
Sbjct: 147 -HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFYENHIKSFMR 205
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE--MKLTSVVVTLWY 203
++ G+D+ H +HRD+K N+L+ G++KLADFGLA+ Y E T+ V+TLWY
Sbjct: 206 QLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWY 265
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
RPPE+LLG RY A+DVWS GC+L +L T++P+ + QL I R
Sbjct: 266 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISR 314
>U04824-1|AAA19586.1| 779|Homo sapiens PITSLRE alpha 2-1 protein.
Length = 779
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 417 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 473
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 474 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 526
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 527 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 586
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 587 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 636
>U04818-1|AAA19584.1| 562|Homo sapiens PITSLRE alpha 2-4 protein.
Length = 562
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 200 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 256
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 257 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 309
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 310 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 369
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 370 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 419
>U04817-1|AAA19583.1| 768|Homo sapiens PITSLRE alpha 2-3 protein.
Length = 768
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 406 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 462
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 463 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 515
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 516 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 575
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 576 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 625
>U04816-1|AAA19582.1| 777|Homo sapiens PITSLRE alpha 2-2 protein.
Length = 777
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 415 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 471
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 472 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 524
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 525 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 584
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 585 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 634
>U04815-1|AAA19581.1| 461|Homo sapiens PITSLRE alpha 1 protein.
Length = 461
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 99 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 155
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 156 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 208
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 209 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 268
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 269 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 318
>M37712-1|AAA36406.1| 439|Homo sapiens p58/GTA protein kinase
protein.
Length = 439
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 77 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 133
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 134 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 186
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 187 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 246
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 247 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 296
>BC139777-1|AAI39778.1| 542|Homo sapiens CDC2L1 protein protein.
Length = 542
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 180 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 236
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 237 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 289
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 290 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 349
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 350 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 399
>BC062579-1|AAH62579.1| 475|Homo sapiens CDC2L1 protein protein.
Length = 475
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 113 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 169
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 170 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 222
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 223 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 282
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 283 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 332
>BC033069-1|AAH33069.1| 508|Homo sapiens CDC2L1 protein protein.
Length = 508
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 146 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 202
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 203 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 255
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 256 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 315
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 316 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 365
>AF080683-5|AAC83666.1| 565|Homo sapiens PITSLRE protein kinase
alpha SV11 isoform protein.
Length = 565
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 203 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 259
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 260 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 312
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 313 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 372
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 373 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 422
>AF080683-4|AAC83663.1| 738|Homo sapiens PITSLRE protein kinase
alpha SV5 isoform protein.
Length = 738
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 376 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 432
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 433 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 485
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 486 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 545
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 546 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 595
>AF080683-3|AAC83665.1| 748|Homo sapiens PITSLRE protein kinase
alpha SV10 isoform protein.
Length = 748
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 386 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 442
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 443 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 495
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 496 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 555
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 556 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 605
>AF080683-2|AAC83662.1| 782|Homo sapiens PITSLRE protein kinase
alpha SV1 isoform protein.
Length = 782
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 420 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 476
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 477 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 529
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 530 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 589
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 590 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 639
>AF080683-1|AAC83664.1| 755|Homo sapiens PITSLRE protein kinase
alpha SV9 isoform protein.
Length = 755
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 393 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 449
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 450 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 502
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 503 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 562
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 563 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 612
>AF067517-1|AAC72082.1| 565|Homo sapiens PITSLRE protein kinase
alpha SV11 isoform protein.
Length = 565
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 203 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 259
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 260 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 312
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 313 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 372
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 373 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 422
>AF067516-1|AAC72081.1| 748|Homo sapiens PITSLRE protein kinase
alpha SV10 isoform protein.
Length = 748
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 386 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 442
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 443 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 495
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 496 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 555
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 556 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 605
>AF067515-1|AAC72080.1| 795|Homo sapiens PITSLRE protein kinase
alpha SV9 isoform protein.
Length = 795
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 433 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 489
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 490 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 542
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 543 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 602
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 603 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 652
>AF067514-1|AAC72079.1| 737|Homo sapiens PITSLRE protein kinase
alpha SV5 isoform protein.
Length = 737
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 375 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 431
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 432 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 484
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 485 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 544
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 545 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 594
>AF067513-1|AAC72078.1| 526|Homo sapiens PITSLRE protein kinase
alpha SV4 isoform protein.
Length = 526
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 164 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 220
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 221 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 273
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 274 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 333
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 334 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 383
>AF067512-1|AAC72077.1| 782|Homo sapiens PITSLRE protein kinase
alpha SV1 isoform protein.
Length = 782
Score = 174 bits (424), Expect = 2e-43
Identities = 90/230 (39%), Positives = 151/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 420 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 476
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 477 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 529
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 530 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 589
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 590 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 639
>BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein.
Length = 324
Score = 174 bits (423), Expect = 3e-43
Identities = 89/227 (39%), Positives = 141/227 (62%), Gaps = 9/227 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K++ + +IG G YG VYKARD + G++VA+KKV++ ++G P++ +REI +LRQL
Sbjct: 90 KFDIIGIIGEGTYGQVYKARD-KDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLT-- 146
Query: 88 RHPNIVRLLDVCHGGQ-CLE-RDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145
H +I+ + ++ + L+ + + +LVFE+++ DL L E+ I+S
Sbjct: 147 -HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMR 205
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE--MKLTSVVVTLWY 203
++ G+D+ H +HRD+K N+L+ G++KLADFGLA+ Y E T+ V+TLWY
Sbjct: 206 QLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWY 265
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
RPPE+LLG RY A+DVWS GC+L +L T++P+ + QL I
Sbjct: 266 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELI 312
>AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein.
Length = 1490
Score = 174 bits (423), Expect = 3e-43
Identities = 90/229 (39%), Positives = 143/229 (62%), Gaps = 9/229 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K++ + +IG G YG VYKARD + G++VA+KKV++ ++G P++ +REI +LRQL
Sbjct: 726 KFDIIGIIGEGTYGQVYKARD-KDTGELVALKKVRLDNEKEGFPITAIREIKILRQLI-- 782
Query: 88 RHPNIVRLLDVCHGGQ-CLE-RDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145
H ++V + ++ Q L+ + + +LVFE+++ DL L E I+S
Sbjct: 783 -HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMK 841
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE--MKLTSVVVTLWY 203
++ G+++ H +HRD+K N+L+ +G++KLADFGLA+ Y+ E T+ V+TLWY
Sbjct: 842 QLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWY 901
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
RPPE+LLG RY A+DVWS GC+L +L T++P+ + QL I R
Sbjct: 902 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISR 950
>AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein.
Length = 1535
Score = 173 bits (420), Expect = 7e-43
Identities = 89/229 (38%), Positives = 143/229 (62%), Gaps = 9/229 (3%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K++ + +IG G YG VYKA+D + G++VA+KKV++ ++G P++ +REI +LRQL
Sbjct: 780 KFDIIGIIGEGTYGQVYKAKD-KDTGELVALKKVRLDNEKEGFPITAIREIKILRQLI-- 836
Query: 88 RHPNIVRLLDVCHGGQ-CLE-RDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145
H ++V + ++ Q L+ + + +LVFE+++ DL L E I+S
Sbjct: 837 -HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMK 895
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE--MKLTSVVVTLWY 203
++ G+++ H +HRD+K N+L+ +G++KLADFGLA+ Y+ E T+ V+TLWY
Sbjct: 896 QLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWY 955
Query: 204 RPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
RPPE+LLG RY A+DVWS GC+L +L T++P+ + QL I R
Sbjct: 956 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISR 1004
>U79269-1|AAB50213.1| 229|Homo sapiens cyclin dependent protein
kinase protein.
Length = 229
Score = 172 bits (419), Expect = 9e-43
Identities = 81/156 (51%), Positives = 111/156 (71%), Gaps = 4/156 (2%)
Query: 96 LDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP-LPESRIRSMSHDIISGVDFL 154
+DVC + D+++ + LVFEHV+QDL ++L +AP P LP I+ + + G+DFL
Sbjct: 1 MDVCATSRT---DREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFL 57
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGARY 214
H++ IVHRDLKP N+LVT G VKLADFGLA+ Y +M LT VVVTLWYR PEVLL + Y
Sbjct: 58 HANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTY 117
Query: 215 CSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
+ +D+WS GC+ A++ R+PL G S++DQL +IF
Sbjct: 118 ATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIF 153
>X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein
kinase protein.
Length = 523
Score = 172 bits (418), Expect = 1e-42
Identities = 91/240 (37%), Positives = 146/240 (60%), Gaps = 17/240 (7%)
Query: 14 ASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS 73
AS++++ F + Y +L +G G Y TVYK R +VA+K++++ E+G P +
Sbjct: 179 ASLSEIG--FGKMETYIKLEKLGEGTYATVYKGRSKLTEN-LVALKEIRLE-HEEGAPCT 234
Query: 74 TVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPG 133
+RE++LL+ L +H NIV L D+ H D+ L L VFE++++DL ++
Sbjct: 235 AIREVSLLKDL---KHANIVTLHDIVH------TDKSLTL--VFEYLDKDLKQYMDDCGN 283
Query: 134 PLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK 193
+ ++ + I+ G+ + H +++HRDLKP NLL+ G +KLADFGLA+ V K
Sbjct: 284 IMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTK 343
Query: 194 -LTSVVVTLWYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
++ VVTLWYRPP+VLLG + Y + +D+W GC+ ++ + RPL PG++ D+LH IFR
Sbjct: 344 TYSNEVVTLWYRPPDVLLGSSEYLTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFR 403
>BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase 2
protein.
Length = 523
Score = 172 bits (418), Expect = 1e-42
Identities = 91/240 (37%), Positives = 146/240 (60%), Gaps = 17/240 (7%)
Query: 14 ASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS 73
AS++++ F + Y +L +G G Y TVYK R +VA+K++++ E+G P +
Sbjct: 179 ASLSEIG--FGKMETYIKLEKLGEGTYATVYKGRSKLTEN-LVALKEIRLE-HEEGAPCT 234
Query: 74 TVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPG 133
+RE++LL+ L +H NIV L D+ H D+ L L VFE++++DL ++
Sbjct: 235 AIREVSLLKDL---KHANIVTLHDIVH------TDKSLTL--VFEYLDKDLKQYMDDCGN 283
Query: 134 PLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK 193
+ ++ + I+ G+ + H +++HRDLKP NLL+ G +KLADFGLA+ V K
Sbjct: 284 IMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTK 343
Query: 194 -LTSVVVTLWYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
++ VVTLWYRPP+VLLG + Y + +D+W GC+ ++ + RPL PG++ D+LH IFR
Sbjct: 344 TYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFR 403
>BC110905-1|AAI10906.1| 397|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 397
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 35 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 91
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 92 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 144
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 145 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 204
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 205 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 254
>BC094827-1|AAH94827.1| 475|Homo sapiens CDC2L2 protein protein.
Length = 475
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 113 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 169
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 170 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 222
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 223 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 282
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 283 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 332
>BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein.
Length = 349
Score = 171 bits (417), Expect = 2e-42
Identities = 93/231 (40%), Positives = 137/231 (59%), Gaps = 16/231 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F A Y L +G G+Y TVYK NG Q+VA+K + + E+G+P + +RE +LL+
Sbjct: 46 FGAASSYLNLEKLGEGSYATVYKGISRING-QLVALKVISMN-AEEGVPFTAIREASLLK 103
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L VFE++ DL ++S+ PG L +R
Sbjct: 104 GL---KHANIVLLHDIIHTKETLT--------FVFEYMHTDLAQYMSQHPGGLHPHNVRL 152
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV-EMKLTSVVVTL 201
++ G+ ++H ++HRDLKP NLL++ G +KLADFGLA+ + +S VVTL
Sbjct: 153 FMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTL 212
Query: 202 WYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASD-SDQLHRIF 250
WYRPP+ LLGA Y S LD+W AGC+ ++ +PL PG S+ +QL +I+
Sbjct: 213 WYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIW 263
>BC014464-1|AAH14464.1| 464|Homo sapiens CDC2L2 protein protein.
Length = 464
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 102 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 158
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 159 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 211
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 212 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 271
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 272 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 321
>AL031282-7|CAI20032.1| 783|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 783
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 421 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 477
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 478 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 530
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 531 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 590
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 591 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 640
>AL031282-6|CAI20034.1| 780|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 780
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 418 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 474
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 475 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 527
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 528 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 587
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 637
>AL031282-5|CAI20031.1| 779|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 779
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 417 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 473
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 474 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 526
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 527 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 586
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 587 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 636
>AL031282-4|CAI20033.1| 770|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 770
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 408 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 464
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 465 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 517
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 518 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 577
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 578 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 627
>AL031282-3|CAI20030.1| 746|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 746
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 384 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 440
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 441 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 493
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 494 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 553
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 603
>AF080694-4|AAC95300.1| 768|Homo sapiens PITSLRE protein kinase
beta SV3 isoform protein.
Length = 768
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 406 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 462
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 463 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 515
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 516 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 575
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 576 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 625
>AF080694-3|AAC95298.1| 781|Homo sapiens PITSLRE protein kinase
beta SV6 isoform protein.
Length = 781
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 419 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 475
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 476 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 528
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 529 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 588
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 589 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 638
>AF080694-2|AAC95297.1| 777|Homo sapiens PITSLRE protein kinase
beta SV2 isoform protein.
Length = 777
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 415 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 471
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 472 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 524
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 525 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 584
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 585 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 634
>AF080694-1|AAC95299.1| 778|Homo sapiens PITSLRE protein kinase
beta SV1 isoform protein.
Length = 778
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 416 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 472
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 473 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 525
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 526 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 585
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 586 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 635
>AF067523-1|AAC72088.1| 397|Homo sapiens PITSLRE protein kinase
beta SV7 isoform protein.
Length = 397
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 35 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 91
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 92 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 144
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 145 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 204
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 205 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 254
>AF067522-1|AAC72087.1| 780|Homo sapiens PITSLRE protein kinase
beta SV6 isoform protein.
Length = 780
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 418 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 474
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 475 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 527
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 528 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 587
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 637
>AF067521-1|AAC72086.1| 767|Homo sapiens PITSLRE protein kinase
beta SV3 isoform protein.
Length = 767
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 405 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 461
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 462 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 514
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 515 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 574
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 575 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 624
>AF067520-1|AAC72085.1| 776|Homo sapiens PITSLRE protein kinase
beta SV2 isoform protein.
Length = 776
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 414 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 470
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 471 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 523
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 524 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 583
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 584 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 633
>AF067519-1|AAC72084.1| 777|Homo sapiens PITSLRE protein kinase
beta SV1 isoform protein.
Length = 777
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 415 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 471
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 472 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 524
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 525 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 584
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 585 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 634
>AF067518-1|AAC72083.1| 397|Homo sapiens PITSLRE protein kinase
beta SV8 isoform protein.
Length = 397
Score = 171 bits (417), Expect = 2e-42
Identities = 89/230 (38%), Positives = 150/230 (65%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 35 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 91
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 92 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 144
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 145 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 204
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 205 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 254
>AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein.
Length = 301
Score = 171 bits (417), Expect = 2e-42
Identities = 93/231 (40%), Positives = 137/231 (59%), Gaps = 16/231 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F A Y L +G G+Y TVYK NG Q+VA+K + + E+G+P + +RE +LL+
Sbjct: 46 FGAASSYLNLEKLGEGSYATVYKGISRING-QLVALKVISMN-AEEGVPFTAIREASLLK 103
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L VFE++ DL ++S+ PG L +R
Sbjct: 104 GL---KHANIVLLHDIIHTKETLT--------FVFEYMHTDLAQYMSQHPGGLHPHNVRL 152
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV-EMKLTSVVVTL 201
++ G+ ++H ++HRDLKP NLL++ G +KLADFGLA+ + +S VVTL
Sbjct: 153 FMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTL 212
Query: 202 WYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASD-SDQLHRIF 250
WYRPP+ LLGA Y S LD+W AGC+ ++ +PL PG S+ +QL +I+
Sbjct: 213 WYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIW 263
>AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein.
Length = 384
Score = 171 bits (417), Expect = 2e-42
Identities = 93/231 (40%), Positives = 137/231 (59%), Gaps = 16/231 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F A Y L +G G+Y TVYK NG Q+VA+K + + E+G+P + +RE +LL+
Sbjct: 46 FGAASSYLNLEKLGEGSYATVYKGISRING-QLVALKVISMN-AEEGVPFTAIREASLLK 103
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L VFE++ DL ++S+ PG L +R
Sbjct: 104 GL---KHANIVLLHDIIHTKETLT--------FVFEYMHTDLAQYMSQHPGGLHPHNVRL 152
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV-EMKLTSVVVTL 201
++ G+ ++H ++HRDLKP NLL++ G +KLADFGLA+ + +S VVTL
Sbjct: 153 FMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTL 212
Query: 202 WYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASD-SDQLHRIF 250
WYRPP+ LLGA Y S LD+W AGC+ ++ +PL PG S+ +QL +I+
Sbjct: 213 WYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIW 263
>M88563-1|AAB59449.1| 446|Homo sapiens p58 protein kinase protein.
Length = 446
Score = 171 bits (416), Expect = 2e-42
Identities = 89/230 (38%), Positives = 149/230 (64%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ +++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 84 RSVDEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 140
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 141 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 193
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 194 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 253
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 254 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 303
>AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein.
Length = 453
Score = 171 bits (416), Expect = 2e-42
Identities = 94/234 (40%), Positives = 137/234 (58%), Gaps = 16/234 (6%)
Query: 20 SALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIA 79
S F A YE+L +G G+Y TVYK + NG ++VA+K +++ E+G P + +RE +
Sbjct: 110 SPKFGKADSYEKLEKLGEGSYATVYKGKSKVNG-KLVALKVIRLQ-EEEGTPFTAIREAS 167
Query: 80 LLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESR 139
LL+ L +H NIV L D+ H + L LVFE+V DL ++ + PG L
Sbjct: 168 LLKGL---KHANIVLLHDIIHTKETLT--------LVFEYVHTDLCQYMDKHPGGLHPDN 216
Query: 140 IRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV-EMKLTSVV 198
++ ++ G+ ++H I+HRDLKP NLL++ G +KLADFGLA+ V ++ V
Sbjct: 217 VKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEV 276
Query: 199 VTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASD-SDQLHRIF 250
VTLWYRPP+VLLG+ Y + LD+W GC+ ++ PG D DQL RIF
Sbjct: 277 VTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIF 330
>U07705-1|AAA19595.1| 775|Homo sapiens PITSLRE isoform PBETA22
protein.
Length = 775
Score = 170 bits (414), Expect = 4e-42
Identities = 89/230 (38%), Positives = 148/230 (64%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ +++ L+ I G YG VY+A+D +IVA+K++K+ +G P++++REI +
Sbjct: 413 RSVDEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKENEGFPITSLREINTI-- 469
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 470 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 522
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 523 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 582
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 583 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 632
>U07704-1|AAA19594.1| 777|Homo sapiens PITSLRE isoform PBETA21
protein.
Length = 777
Score = 170 bits (414), Expect = 4e-42
Identities = 89/230 (38%), Positives = 148/230 (64%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ +++ L+ I G YG VY+A+D +IVA+K++K+ +G P++++REI +
Sbjct: 415 RSVDEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKENEGFPITSLREINTI-- 471
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 472 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 524
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 525 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 584
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 585 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 634
>U04819-1|AAA19585.1| 439|Homo sapiens PITSLRE beta 1 protein.
Length = 439
Score = 170 bits (414), Expect = 4e-42
Identities = 89/230 (38%), Positives = 148/230 (64%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ +++ L+ I G YG VY+A+D +IVA+K++K+ +G P++++REI +
Sbjct: 77 RSVDEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKENEGFPITSLREINTI-- 133
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 134 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 186
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+HRDLK NLL++ AG +K+ DFGLA+ Y +K T VVVT W
Sbjct: 187 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 246
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 247 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 296
>AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase 3
isoform b protein.
Length = 504
Score = 170 bits (414), Expect = 4e-42
Identities = 92/240 (38%), Positives = 144/240 (60%), Gaps = 17/240 (7%)
Query: 14 ASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS 73
AS++D+ F + Y +L +G G Y TV+K R +VA+K++++ E+G P +
Sbjct: 161 ASLSDIG--FGKLETYVKLDKLGEGTYATVFKGRSKLTEN-LVALKEIRLE-HEEGAPCT 216
Query: 74 TVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPG 133
+RE++LL+ L +H NIV L D+ H D+ L L VFE+++ DL +L
Sbjct: 217 AIREVSLLKNL---KHANIVTLHDLIH------TDRSLTL--VFEYLDSDLKQYLDHCGN 265
Query: 134 PLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK 193
+ ++ ++ G+ + H +I+HRDLKP NLL+ G +KLADFGLA+ V K
Sbjct: 266 LMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK 325
Query: 194 -LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
++ VVTLWYRPP+VLLG+ Y + +D+W GC+ ++ T RPL PG++ ++LH IFR
Sbjct: 326 TYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 385
>AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase 3
isoform a protein.
Length = 474
Score = 170 bits (414), Expect = 4e-42
Identities = 92/240 (38%), Positives = 144/240 (60%), Gaps = 17/240 (7%)
Query: 14 ASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS 73
AS++D+ F + Y +L +G G Y TV+K R +VA+K++++ E+G P +
Sbjct: 131 ASLSDIG--FGKLETYVKLDKLGEGTYATVFKGRSKLTEN-LVALKEIRLE-HEEGAPCT 186
Query: 74 TVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPG 133
+RE++LL+ L +H NIV L D+ H D+ L L VFE+++ DL +L
Sbjct: 187 AIREVSLLKNL---KHANIVTLHDLIH------TDRSLTL--VFEYLDSDLKQYLDHCGN 235
Query: 134 PLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK 193
+ ++ ++ G+ + H +I+HRDLKP NLL+ G +KLADFGLA+ V K
Sbjct: 236 LMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK 295
Query: 194 -LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
++ VVTLWYRPP+VLLG+ Y + +D+W GC+ ++ T RPL PG++ ++LH IFR
Sbjct: 296 TYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 355
>AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 170 bits (414), Expect = 4e-42
Identities = 92/240 (38%), Positives = 144/240 (60%), Gaps = 17/240 (7%)
Query: 14 ASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS 73
AS++D+ F + Y +L +G G Y TV+K R +VA+K++++ E+G P +
Sbjct: 129 ASLSDIG--FGKLETYVKLDKLGEGTYATVFKGRSKLTEN-LVALKEIRLE-HEEGAPCT 184
Query: 74 TVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPG 133
+RE++LL+ L +H NIV L D+ H D+ L L VFE+++ DL +L
Sbjct: 185 AIREVSLLKNL---KHANIVTLHDLIH------TDRSLTL--VFEYLDSDLKQYLDHCGN 233
Query: 134 PLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK 193
+ ++ ++ G+ + H +I+HRDLKP NLL+ G +KLADFGLA+ V K
Sbjct: 234 LMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK 293
Query: 194 -LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
++ VVTLWYRPP+VLLG+ Y + +D+W GC+ ++ T RPL PG++ ++LH IFR
Sbjct: 294 TYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 353
>AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase 3
isoform b variant protein.
Length = 436
Score = 170 bits (414), Expect = 4e-42
Identities = 92/240 (38%), Positives = 144/240 (60%), Gaps = 17/240 (7%)
Query: 14 ASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS 73
AS++D+ F + Y +L +G G Y TV+K R +VA+K++++ E+G P +
Sbjct: 93 ASLSDIG--FGKLETYVKLDKLGEGTYATVFKGRSKLTEN-LVALKEIRLE-HEEGAPCT 148
Query: 74 TVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPG 133
+RE++LL+ L +H NIV L D+ H D+ L L VFE+++ DL +L
Sbjct: 149 AIREVSLLKNL---KHANIVTLHDLIH------TDRSLTL--VFEYLDSDLKQYLDHCGN 197
Query: 134 PLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK 193
+ ++ ++ G+ + H +I+HRDLKP NLL+ G +KLADFGLA+ V K
Sbjct: 198 LMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK 257
Query: 194 -LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
++ VVTLWYRPP+VLLG+ Y + +D+W GC+ ++ T RPL PG++ ++LH IFR
Sbjct: 258 TYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 317
>BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein
kinase 3 protein.
Length = 472
Score = 169 bits (412), Expect = 6e-42
Identities = 92/240 (38%), Positives = 144/240 (60%), Gaps = 17/240 (7%)
Query: 14 ASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS 73
AS++D+ F + Y +L +G G Y TV+K R +VA+K++++ E+G P +
Sbjct: 129 ASLSDIG--FGKLETYVKLDKLGEGTYATVFKGRSKLMEN-LVALKEIRLE-HEEGAPCT 184
Query: 74 TVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPG 133
+RE++LL+ L +H NIV L D+ H D+ L L VFE+++ DL +L
Sbjct: 185 AIREVSLLKNL---KHANIVTLHDLIH------TDRSLTL--VFEYLDSDLKQYLDHCGN 233
Query: 134 PLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK 193
+ ++ ++ G+ + H +I+HRDLKP NLL+ G +KLADFGLA+ V K
Sbjct: 234 LMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK 293
Query: 194 -LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
++ VVTLWYRPP+VLLG+ Y + +D+W GC+ ++ T RPL PG++ ++LH IFR
Sbjct: 294 TYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 353
>BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 169 bits (412), Expect = 6e-42
Identities = 92/240 (38%), Positives = 144/240 (60%), Gaps = 17/240 (7%)
Query: 14 ASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS 73
AS++D+ F + Y +L +G G Y TV+K R +VA+K++++ E+G P +
Sbjct: 129 ASLSDIG--FGKLETYVKLDKLGEGTYATVFKGRSKLMEN-LVALKEIRLE-HEEGAPCT 184
Query: 74 TVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPG 133
+RE++LL+ L +H NIV L D+ H D+ L L VFE+++ DL +L
Sbjct: 185 AIREVSLLKNL---KHANIVTLHDLIH------TDRSLTL--VFEYLDSDLKQYLDHCGN 233
Query: 134 PLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK 193
+ ++ ++ G+ + H +I+HRDLKP NLL+ G +KLADFGLA+ V K
Sbjct: 234 LMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK 293
Query: 194 -LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
++ VVTLWYRPP+VLLG+ Y + +D+W GC+ ++ T RPL PG++ ++LH IFR
Sbjct: 294 TYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 353
>L25676-1|AAA35668.1| 372|Homo sapiens CDC2-related kinase protein.
Length = 372
Score = 169 bits (411), Expect = 8e-42
Identities = 88/225 (39%), Positives = 141/225 (62%), Gaps = 10/225 (4%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
KYE+L+ IG G +G V+KAR GQ VA+KKV + ++G P++ +REI +L+ L
Sbjct: 18 KYEKLAKIGQGTFGEVFKARH-RKTGQKVALKKVLMENEKEGFPITALREIKILQLL--- 73
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+H N+V L+++C + ++LVF+ E DL LS S I+ + +
Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQML 133
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEM-----KLTSVVVTLW 202
++G+ ++H ++I+HRD+K N+L+T G +KLADFGLA+ + + + T+ VVTLW
Sbjct: 134 LNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLW 193
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246
YRPPE+LLG R Y +D+W AGC++A++ TR P++ G ++ QL
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQL 238
>BC001968-1|AAH01968.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 169 bits (411), Expect = 8e-42
Identities = 88/225 (39%), Positives = 141/225 (62%), Gaps = 10/225 (4%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
KYE+L+ IG G +G V+KAR GQ VA+KKV + ++G P++ +REI +L+ L
Sbjct: 18 KYEKLAKIGQGTFGEVFKARH-RKTGQKVALKKVLMENEKEGFPITALREIKILQLL--- 73
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+H N+V L+++C + ++LVF+ E DL LS S I+ + +
Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQML 133
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEM-----KLTSVVVTLW 202
++G+ ++H ++I+HRD+K N+L+T G +KLADFGLA+ + + + T+ VVTLW
Sbjct: 134 LNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLW 193
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246
YRPPE+LLG R Y +D+W AGC++A++ TR P++ G ++ QL
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQL 238
>AL162586-9|CAI39768.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 169 bits (411), Expect = 8e-42
Identities = 88/225 (39%), Positives = 141/225 (62%), Gaps = 10/225 (4%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
KYE+L+ IG G +G V+KAR GQ VA+KKV + ++G P++ +REI +L+ L
Sbjct: 18 KYEKLAKIGQGTFGEVFKARH-RKTGQKVALKKVLMENEKEGFPITALREIKILQLL--- 73
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+H N+V L+++C + ++LVF+ E DL LS S I+ + +
Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQML 133
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEM-----KLTSVVVTLW 202
++G+ ++H ++I+HRD+K N+L+T G +KLADFGLA+ + + + T+ VVTLW
Sbjct: 134 LNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLW 193
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246
YRPPE+LLG R Y +D+W AGC++A++ TR P++ G ++ QL
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQL 238
>AF517840-1|AAM54039.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 169 bits (411), Expect = 8e-42
Identities = 88/225 (39%), Positives = 141/225 (62%), Gaps = 10/225 (4%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
KYE+L+ IG G +G V+KAR GQ VA+KKV + ++G P++ +REI +L+ L
Sbjct: 18 KYEKLAKIGQGTFGEVFKARH-RKTGQKVALKKVLMENEKEGFPITALREIKILQLL--- 73
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+H N+V L+++C + ++LVF+ E DL LS S I+ + +
Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQML 133
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEM-----KLTSVVVTLW 202
++G+ ++H ++I+HRD+K N+L+T G +KLADFGLA+ + + + T+ VVTLW
Sbjct: 134 LNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLW 193
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246
YRPPE+LLG R Y +D+W AGC++A++ TR P++ G ++ QL
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQL 238
>AF174497-1|AAF36538.1| 565|Homo sapiens GR AF-1 coactivator 3
protein.
Length = 565
Score = 169 bits (410), Expect = 1e-41
Identities = 88/230 (38%), Positives = 149/230 (64%), Gaps = 12/230 (5%)
Query: 24 QNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQ 83
++ ++++ L+ I G YG VY+A+D +IVA+K++K+ ++G P++++REI +
Sbjct: 203 RSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTI-- 259
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+A +HPNIV + ++ G D+ +++V +VE DL S + P ++++
Sbjct: 260 LKA-QHPNIVTVREIVVGSNM---DK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTL 312
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ GV LH + I+ RDLK LL++ AG +K+ DFGLA+ Y +K T VVVTLW
Sbjct: 313 MIQLLRGVKHLHDNWILQRDLKTSTLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLW 372
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YR PE+LLGA+ Y +A+D+WS GC+ +L T++PL PG S+ DQ++++F+
Sbjct: 373 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 422
>X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein
kinase protein.
Length = 380
Score = 168 bits (408), Expect = 2e-41
Identities = 91/240 (37%), Positives = 144/240 (60%), Gaps = 17/240 (7%)
Query: 14 ASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLS 73
AS++D+ F + Y +L +G G Y TV+K R +VA+K++++ E+G P +
Sbjct: 37 ASLSDIG--FGKLETYVKLDKLGEGTYATVFKGRSKLTEN-LVALKEIRLE-HEEGAPCT 92
Query: 74 TVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPG 133
+RE++LL+ L +H NIV L D+ H D+ L L VFE+++ DL +L
Sbjct: 93 AIREVSLLKNL---KHANIVTLHDLIH------TDRSLTL--VFEYLDSDLKQYLDHCGN 141
Query: 134 PLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK 193
+ ++ ++ G+ + H+ +I+HRDLKP NLL+ G +KLADFGLA+ V K
Sbjct: 142 LMSMHNVKIFMFQLLRGLAYCHTRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTK 201
Query: 194 -LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
++ VVTLWYRPP+VLLG+ Y + + +W GC+ ++ T RPL PG++ ++LH IFR
Sbjct: 202 TYSNEVVTLWYRPPDVLLGSTEYSTPIAMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 261
>BT019903-1|AAV38706.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 168 bits (408), Expect = 2e-41
Identities = 88/225 (39%), Positives = 140/225 (62%), Gaps = 10/225 (4%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
KYE+L+ IG G +G V+KAR GQ VA+KKV + ++G P++ +REI +L+ L
Sbjct: 18 KYEKLAKIGQGTFGEVFKARH-RKTGQKVALKKVLMENEKEGFPITALREIKILQLL--- 73
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+H N+V L+++C + ++LVF+ E DL LS S I+ + +
Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQML 133
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEM-----KLTSVVVTLW 202
++G+ ++H ++I+HRD+K N+L+T G KLADFGLA+ + + + T+ VVTLW
Sbjct: 134 LNGLYYIHRNKILHRDMKAANVLITRDGVPKLADFGLARAFSLAKNSQPNRYTNRVVTLW 193
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246
YRPPE+LLG R Y +D+W AGC++A++ TR P++ G ++ QL
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQL 238
>AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protein
kinase PFTAIRE-1 protein.
Length = 469
Score = 168 bits (408), Expect = 2e-41
Identities = 93/234 (39%), Positives = 136/234 (58%), Gaps = 16/234 (6%)
Query: 20 SALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIA 79
S F A YE+L +G G+Y TVYK + N ++VA+K +++ E+G P + +RE +
Sbjct: 126 SPKFGKADSYEKLEKLGEGSYATVYKGKSKVNW-KLVALKVIRLQ-EEEGTPFTAIREAS 183
Query: 80 LLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESR 139
LL+ L +H NIV L D+ H + L LVFE+V DL ++ + PG L
Sbjct: 184 LLKGL---KHANIVLLHDIIHTKETLT--------LVFEYVHTDLCQYMDKHPGGLHPDN 232
Query: 140 IRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV-EMKLTSVV 198
++ ++ G+ ++H I+HRDLKP NLL++ G +KLADFGLA+ V ++ V
Sbjct: 233 VKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEV 292
Query: 199 VTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASD-SDQLHRIF 250
VTLWYRPP+VLLG+ Y + LD+W GC+ ++ PG D DQL RIF
Sbjct: 293 VTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIF 346
>X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein
kinase protein.
Length = 496
Score = 167 bits (406), Expect = 3e-41
Identities = 86/231 (37%), Positives = 138/231 (59%), Gaps = 15/231 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F + Y +L +G G Y TVYK + +VA+K++++ E+G P + +RE++LL+
Sbjct: 159 FGKLETYIKLDKLGEGTYATVYKGKSKLTDN-LVALKEIRLE-HEEGAPCTAIREVSLLK 216
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L LVFE++++DL +L + ++
Sbjct: 217 DL---KHANIVTLHDIIHTEKSLT--------LVFEYLDKDLKQYLDDCGNIINMHNVKL 265
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTL 201
++ G+ + H +++HRDLKP NLL+ G +KLADFGLA+ + K ++ VVTL
Sbjct: 266 FLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTL 325
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYRPP++LLG+ Y + +D+W GC+ ++ T RPL PG++ +QLH IFR
Sbjct: 326 WYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 376
>BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 167 bits (406), Expect = 3e-41
Identities = 86/231 (37%), Positives = 138/231 (59%), Gaps = 15/231 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F + Y +L +G G Y TVYK + +VA+K++++ E+G P + +RE++LL+
Sbjct: 159 FGKLETYIKLDKLGEGTYATVYKGKSKLTDN-LVALKEIRLE-HEEGAPCTAIREVSLLK 216
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L LVFE++++DL +L + ++
Sbjct: 217 DL---KHANIVTLHDIIHTEKSLT--------LVFEYLDKDLKQYLDDCGNIINMHNVKL 265
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTL 201
++ G+ + H +++HRDLKP NLL+ G +KLADFGLA+ + K ++ VVTL
Sbjct: 266 FLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTL 325
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYRPP++LLG+ Y + +D+W GC+ ++ T RPL PG++ +QLH IFR
Sbjct: 326 WYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 376
>BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 167 bits (406), Expect = 3e-41
Identities = 86/231 (37%), Positives = 138/231 (59%), Gaps = 15/231 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F + Y +L +G G Y TVYK + +VA+K++++ E+G P + +RE++LL+
Sbjct: 159 FGKLETYIKLDKLGEGTYATVYKGKSKLTDN-LVALKEIRLE-HEEGAPCTAIREVSLLK 216
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L LVFE++++DL +L + ++
Sbjct: 217 DL---KHANIVTLHDIIHTEKSLT--------LVFEYLDKDLKQYLDDCGNIINMHNVKL 265
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTL 201
++ G+ + H +++HRDLKP NLL+ G +KLADFGLA+ + K ++ VVTL
Sbjct: 266 FLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTL 325
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYRPP++LLG+ Y + +D+W GC+ ++ T RPL PG++ +QLH IFR
Sbjct: 326 WYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 376
>BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein.
Length = 395
Score = 167 bits (406), Expect = 3e-41
Identities = 86/231 (37%), Positives = 138/231 (59%), Gaps = 15/231 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F + Y +L +G G Y TVYK + +VA+K++++ E+G P + +RE++LL+
Sbjct: 58 FGKLETYIKLDKLGEGTYATVYKGKSKLTDN-LVALKEIRLE-HEEGAPCTAIREVSLLK 115
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L LVFE++++DL +L + ++
Sbjct: 116 DL---KHANIVTLHDIIHTEKSLT--------LVFEYLDKDLKQYLDDCGNIINMHNVKL 164
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTL 201
++ G+ + H +++HRDLKP NLL+ G +KLADFGLA+ + K ++ VVTL
Sbjct: 165 FLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTL 224
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYRPP++LLG+ Y + +D+W GC+ ++ T RPL PG++ +QLH IFR
Sbjct: 225 WYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 275
>BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein.
Length = 448
Score = 167 bits (406), Expect = 3e-41
Identities = 86/231 (37%), Positives = 138/231 (59%), Gaps = 15/231 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F + Y +L +G G Y TVYK + +VA+K++++ E+G P + +RE++LL+
Sbjct: 111 FGKLETYIKLDKLGEGTYATVYKGKSKLTDN-LVALKEIRLE-HEEGAPCTAIREVSLLK 168
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L LVFE++++DL +L + ++
Sbjct: 169 DL---KHANIVTLHDIIHTEKSLT--------LVFEYLDKDLKQYLDDCGNIINMHNVKL 217
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTL 201
++ G+ + H +++HRDLKP NLL+ G +KLADFGLA+ + K ++ VVTL
Sbjct: 218 FLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTL 277
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYRPP++LLG+ Y + +D+W GC+ ++ T RPL PG++ +QLH IFR
Sbjct: 278 WYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 328
>BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 167 bits (406), Expect = 3e-41
Identities = 86/231 (37%), Positives = 138/231 (59%), Gaps = 15/231 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F + Y +L +G G Y TVYK + +VA+K++++ E+G P + +RE++LL+
Sbjct: 159 FGKLETYIKLDKLGEGTYATVYKGKSKLTDN-LVALKEIRLE-HEEGAPCTAIREVSLLK 216
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L LVFE++++DL +L + ++
Sbjct: 217 DL---KHANIVTLHDIIHTEKSLT--------LVFEYLDKDLKQYLDDCGNIINMHNVKL 265
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTL 201
++ G+ + H +++HRDLKP NLL+ G +KLADFGLA+ + K ++ VVTL
Sbjct: 266 FLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTL 325
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYRPP++LLG+ Y + +D+W GC+ ++ T RPL PG++ +QLH IFR
Sbjct: 326 WYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 376
>AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 167 bits (406), Expect = 3e-41
Identities = 86/231 (37%), Positives = 138/231 (59%), Gaps = 15/231 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F + Y +L +G G Y TVYK + +VA+K++++ E+G P + +RE++LL+
Sbjct: 159 FGKLETYIKLDKLGEGTYATVYKGKSKLTDN-LVALKEIRLE-HEEGAPCTAIREVSLLK 216
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L LVFE++++DL +L + ++
Sbjct: 217 DL---KHANIVTLHDIIHTEKSLT--------LVFEYLDKDLKQYLDDCGNIINMHNVKL 265
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTL 201
++ G+ + H +++HRDLKP NLL+ G +KLADFGLA+ + K ++ VVTL
Sbjct: 266 FLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTL 325
Query: 202 WYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYRPP++LLG+ Y + +D+W GC+ ++ T RPL PG++ +QLH IFR
Sbjct: 326 WYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR 376
>X80230-1|CAA56516.1| 372|Homo sapiens serine/threonine protein
kinase protein.
Length = 372
Score = 167 bits (405), Expect = 4e-41
Identities = 87/225 (38%), Positives = 140/225 (62%), Gaps = 10/225 (4%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
KYE+L+ IG G +G V+KAR GQ VA+KKV + ++G P++ +REI +L+ L
Sbjct: 18 KYEKLAKIGQGTFGEVFKARH-RKTGQKVALKKVLMENEKEGFPITALREIKILQLL--- 73
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+H N+V L+++C + ++LVF+ E DL LS S I+ + +
Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQML 133
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEM-----KLTSVVVTLW 202
++G+ ++H ++I+HRD+K N+L+T G +KLADFGLA+ + + + T+ VVTLW
Sbjct: 134 LNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLW 193
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246
YRPPE+LLG R Y +D+W AGC++A++ TR P++ ++ QL
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQANTEQHQL 238
>AF255306-1|AAF72183.1| 372|Homo sapiens protein kinase CDK9
protein.
Length = 372
Score = 167 bits (405), Expect = 4e-41
Identities = 87/225 (38%), Positives = 140/225 (62%), Gaps = 10/225 (4%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
KYE+L+ IG G +G V+KAR GQ VA+KKV + ++G P++ +REI +L+ L
Sbjct: 18 KYEKLAKIGQGTFGEVFKARH-RKTGQKVALKKVLMENEKEGFPITALREIKILQLL--- 73
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+H N+V L+++C + ++LVF+ E DL LS S I+ + +
Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQML 133
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEM-----KLTSVVVTLW 202
++G+ ++H ++I+HRD+K N+L+T G +KLADFGLA+ + + + T+ VVTLW
Sbjct: 134 LNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLW 193
Query: 203 YRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQL 246
YRPPE+LLG R Y +D+W AGC++A++ TR P++ ++ QL
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQANTEQHQL 238
>U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinase
protein.
Length = 493
Score = 166 bits (403), Expect = 8e-41
Identities = 93/225 (41%), Positives = 134/225 (59%), Gaps = 14/225 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+KYE L L+G G+YG V K R+ + G+IVA+KK + + + +REI LL+QL
Sbjct: 2 EKYENLGLVGEGSYGMVMKCRN-KDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
RH N+V LL+VC ++ +LVFE V+ + L P L ++
Sbjct: 59 -RHENLVNLLEVCK--------KKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQ 109
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWYRP 205
II+G+ F HSH I+HRD+KP N+LV+ +G VKL DFG A+T ++ T V T WYR
Sbjct: 110 IINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRA 169
Query: 206 PEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE+L+G +Y A+DVW+ GC++ ++ PL PG SD DQL+ I
Sbjct: 170 PELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHI 214
>BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 166 bits (403), Expect = 8e-41
Identities = 93/225 (41%), Positives = 134/225 (59%), Gaps = 14/225 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+KYE L L+G G+YG V K R+ + G+IVA+KK + + + +REI LL+QL
Sbjct: 2 EKYENLGLVGEGSYGMVMKCRN-KDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
RH N+V LL+VC ++ +LVFE V+ + L P L ++
Sbjct: 59 -RHENLVNLLEVCK--------KKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQ 109
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWYRP 205
II+G+ F HSH I+HRD+KP N+LV+ +G VKL DFG A+T ++ T V T WYR
Sbjct: 110 IINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRA 169
Query: 206 PEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE+L+G +Y A+DVW+ GC++ ++ PL PG SD DQL+ I
Sbjct: 170 PELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHI 214
>BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 166 bits (403), Expect = 8e-41
Identities = 93/225 (41%), Positives = 134/225 (59%), Gaps = 14/225 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+KYE L L+G G+YG V K R+ + G+IVA+KK + + + +REI LL+QL
Sbjct: 2 EKYENLGLVGEGSYGMVMKCRN-KDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
RH N+V LL+VC ++ +LVFE V+ + L P L ++
Sbjct: 59 -RHENLVNLLEVCK--------KKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQ 109
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWYRP 205
II+G+ F HSH I+HRD+KP N+LV+ +G VKL DFG A+T ++ T V T WYR
Sbjct: 110 IINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRA 169
Query: 206 PEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE+L+G +Y A+DVW+ GC++ ++ PL PG SD DQL+ I
Sbjct: 170 PELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHI 214
>AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent
kinase-like 4 protein.
Length = 379
Score = 164 bits (398), Expect = 3e-40
Identities = 88/227 (38%), Positives = 137/227 (60%), Gaps = 13/227 (5%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+KYE+L+ G G+YG V+K R+ GQ+VA+KK + + + +REI +L+QL
Sbjct: 2 EKYEKLAKTGEGSYGVVFKCRN-KTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+HPN+V L++V R +++ LVFE+ + L + L R P + + I+S+
Sbjct: 59 -KHPNLVNLIEV------FRRKRKM--HLVFEYCDHTLLNELERNPNGVADGVIKSVLWQ 109
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
+ ++F H H +HRD+KP N+L+T G +K+ DFG A+ T V T WYR P
Sbjct: 110 TLQALNFCHIHNCIHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAP 169
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
E+L+G +Y S++D+W+ GCV A+L T +PL PG SD DQL+ I R+
Sbjct: 170 ELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRT 216
>AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent
kinase-like 4 protein.
Length = 315
Score = 164 bits (398), Expect = 3e-40
Identities = 88/227 (38%), Positives = 137/227 (60%), Gaps = 13/227 (5%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+KYE+L+ G G+YG V+K R+ GQ+VA+KK + + + +REI +L+QL
Sbjct: 2 EKYEKLAKTGEGSYGVVFKCRN-KTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQL-- 58
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+HPN+V L++V R +++ LVFE+ + L + L R P + + I+S+
Sbjct: 59 -KHPNLVNLIEV------FRRKRKM--HLVFEYCDHTLLNELERNPNGVADGVIKSVLWQ 109
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
+ ++F H H +HRD+KP N+L+T G +K+ DFG A+ T V T WYR P
Sbjct: 110 TLQALNFCHIHNCIHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAP 169
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRS 252
E+L+G +Y S++D+W+ GCV A+L T +PL PG SD DQL+ I R+
Sbjct: 170 ELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRT 216
>BC025301-1|AAH25301.1| 272|Homo sapiens CDK10 protein protein.
Length = 272
Score = 161 bits (392), Expect = 2e-39
Identities = 88/185 (47%), Positives = 121/185 (65%), Gaps = 11/185 (5%)
Query: 67 EDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDS 126
+DGIP+S++REI LL +L RHPNIV L +V G LE +FLV + EQDL S
Sbjct: 5 KDGIPISSLREITLLLRL---RHPNIVELKEVVVGNH-LES-----IFLVMGYCEQDLAS 55
Query: 127 FLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK 186
L P P E++++ + ++ G+ +LH + I+HRDLK NLL+T G VK ADFGLA+
Sbjct: 56 LLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLAR 115
Query: 187 TYDVEMK-LTSVVVTLWYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSD 244
Y V +K +T VVTLWYR PE+LLG +++D+W+ GC+LA+L RPLLPG S+
Sbjct: 116 AYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIH 175
Query: 245 QLHRI 249
Q+ I
Sbjct: 176 QIDLI 180
>BC017342-1|AAH17342.1| 283|Homo sapiens CDK10 protein protein.
Length = 283
Score = 161 bits (392), Expect = 2e-39
Identities = 88/185 (47%), Positives = 121/185 (65%), Gaps = 11/185 (5%)
Query: 67 EDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDS 126
+DGIP+S++REI LL +L RHPNIV L +V G LE +FLV + EQDL S
Sbjct: 5 KDGIPISSLREITLLLRL---RHPNIVELKEVVVGNH-LES-----IFLVMGYCEQDLAS 55
Query: 127 FLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK 186
L P P E++++ + ++ G+ +LH + I+HRDLK NLL+T G VK ADFGLA+
Sbjct: 56 LLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLAR 115
Query: 187 TYDVEMK-LTSVVVTLWYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSD 244
Y V +K +T VVTLWYR PE+LLG +++D+W+ GC+LA+L RPLLPG S+
Sbjct: 116 AYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIH 175
Query: 245 QLHRI 249
Q+ I
Sbjct: 176 QIDLI 180
>AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kinase
protein.
Length = 346
Score = 161 bits (391), Expect = 2e-39
Identities = 92/228 (40%), Positives = 137/228 (60%), Gaps = 16/228 (7%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
+Y L IG GA+G V+KA+ + G +IVA+KKV + EDG P +REI L+++E
Sbjct: 3 QYCILGRIGEGAHGIVFKAKHVETG-EIVALKKVALRRLEDGFPNQALREIKALQEMEDN 61
Query: 88 RHPNIVRLLDVC-HGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
++ +V+L V HGG + L FE + DL + A PL +++++S
Sbjct: 62 QY--VVQLKAVFPHGGGFV---------LAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQM 110
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY--DVEMKLTSVVVTLWYR 204
++ GV F H++ IVHRDLKP NLL++ +G++K+ADFGLA+ + D T V T WYR
Sbjct: 111 LLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYR 170
Query: 205 PPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
PE+L GAR Y +D+WS GC++ +L PL PG +D +QL + R
Sbjct: 171 APELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLR 218
>AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kinase
protein.
Length = 346
Score = 161 bits (391), Expect = 2e-39
Identities = 92/228 (40%), Positives = 137/228 (60%), Gaps = 16/228 (7%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
+Y L IG GA+G V+KA+ + G +IVA+KKV + EDG P +REI L+++E
Sbjct: 3 QYCILGRIGEGAHGIVFKAKHVETG-EIVALKKVALRRLEDGFPNQALREIKALQEMEDN 61
Query: 88 RHPNIVRLLDVC-HGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
++ +V+L V HGG + L FE + DL + A PL +++++S
Sbjct: 62 QY--VVQLKAVFPHGGGFV---------LAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQM 110
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY--DVEMKLTSVVVTLWYR 204
++ GV F H++ IVHRDLKP NLL++ +G++K+ADFGLA+ + D T V T WYR
Sbjct: 111 LLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYR 170
Query: 205 PPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
PE+L GAR Y +D+WS GC++ +L PL PG +D +QL + R
Sbjct: 171 APELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLR 218
>X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein
kinase protein.
Length = 358
Score = 155 bits (377), Expect = 1e-37
Identities = 90/225 (40%), Positives = 132/225 (58%), Gaps = 14/225 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+KYE++ IG G+YG V+K R+ + GQIVA+KK + + I +REI +L+QL
Sbjct: 3 EKYEKIGKIGEGSYGVVFKCRN-RDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQL-- 59
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+HPN+V LL+V R ++L LVFE+ + + L R +PE ++S++
Sbjct: 60 -KHPNLVNLLEV------FRRKRRL--HLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQ 110
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYRP 205
+ V+F H H +HRD+KP N+L+T +KL DFG A+ T V T WYR
Sbjct: 111 TLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRS 170
Query: 206 PEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE+L+G +Y +DVW+ GCV A+L + PL PG SD DQL+ I
Sbjct: 171 PELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLI 215
>BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 155 bits (377), Expect = 1e-37
Identities = 90/225 (40%), Positives = 132/225 (58%), Gaps = 14/225 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+KYE++ IG G+YG V+K R+ + GQIVA+KK + + I +REI +L+QL
Sbjct: 3 EKYEKIGKIGEGSYGVVFKCRN-RDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQL-- 59
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+HPN+V LL+V R ++L LVFE+ + + L R +PE ++S++
Sbjct: 60 -KHPNLVNLLEV------FRRKRRL--HLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQ 110
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYRP 205
+ V+F H H +HRD+KP N+L+T +KL DFG A+ T V T WYR
Sbjct: 111 TLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRS 170
Query: 206 PEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE+L+G +Y +DVW+ GCV A+L + PL PG SD DQL+ I
Sbjct: 171 PELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLI 215
>AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 155 bits (377), Expect = 1e-37
Identities = 90/225 (40%), Positives = 132/225 (58%), Gaps = 14/225 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+KYE++ IG G+YG V+K R+ + GQIVA+KK + + I +REI +L+QL
Sbjct: 3 EKYEKIGKIGEGSYGVVFKCRN-RDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQL-- 59
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+HPN+V LL+V R ++L LVFE+ + + L R +PE ++S++
Sbjct: 60 -KHPNLVNLLEV------FRRKRRL--HLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQ 110
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLWYRP 205
+ V+F H H +HRD+KP N+L+T +KL DFG A+ T V T WYR
Sbjct: 111 TLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRS 170
Query: 206 PEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE+L+G +Y +DVW+ GCV A+L + PL PG SD DQL+ I
Sbjct: 171 PELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLI 215
>Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-like
5 protein.
Length = 1030
Score = 153 bits (372), Expect = 4e-37
Identities = 85/224 (37%), Positives = 128/224 (57%), Gaps = 14/224 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K+E L ++G GAYG V K R +IVA+KK K + + + +T+RE+ +LR L
Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETH-EIVAIKKFKDSEENEEVKETTLRELKMLRTL--- 67
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+ NIV L + ++ L+LVFE+VE+++ L P +P +++S + +
Sbjct: 68 KQENIVELKEAFR--------RRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQL 119
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV--EMKLTSVVVTLWYRP 205
I + + H + IVHRD+KP NLL++ +KL DFG A+ T V T WYR
Sbjct: 120 IKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRS 179
Query: 206 PEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE+LLGA Y ++D+WS GC+L +L +PL PG S+ DQL I
Sbjct: 180 PELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTI 223
>Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein.
Length = 1030
Score = 153 bits (372), Expect = 4e-37
Identities = 85/224 (37%), Positives = 128/224 (57%), Gaps = 14/224 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K+E L ++G GAYG V K R +IVA+KK K + + + +T+RE+ +LR L
Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETH-EIVAIKKFKDSEENEEVKETTLRELKMLRTL--- 67
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+ NIV L + ++ L+LVFE+VE+++ L P +P +++S + +
Sbjct: 68 KQENIVELKEAFR--------RRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQL 119
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV--EMKLTSVVVTLWYRP 205
I + + H + IVHRD+KP NLL++ +KL DFG A+ T V T WYR
Sbjct: 120 IKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRS 179
Query: 206 PEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE+LLGA Y ++D+WS GC+L +L +PL PG S+ DQL I
Sbjct: 180 PELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTI 223
>AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase 9
protein.
Length = 1030
Score = 153 bits (372), Expect = 4e-37
Identities = 85/224 (37%), Positives = 128/224 (57%), Gaps = 14/224 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K+E L ++G GAYG V K R +IVA+KK K + + + +T+RE+ +LR L
Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETH-EIVAIKKFKDSEENEEVKETTLRELKMLRTL--- 67
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+ NIV L + ++ L+LVFE+VE+++ L P +P +++S + +
Sbjct: 68 KQENIVELKEAFR--------RRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQL 119
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV--EMKLTSVVVTLWYRP 205
I + + H + IVHRD+KP NLL++ +KL DFG A+ T V T WYR
Sbjct: 120 IKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRS 179
Query: 206 PEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE+LLGA Y ++D+WS GC+L +L +PL PG S+ DQL I
Sbjct: 180 PELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTI 223
>AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent
kinase-like 5 protein.
Length = 1030
Score = 153 bits (372), Expect = 4e-37
Identities = 85/224 (37%), Positives = 128/224 (57%), Gaps = 14/224 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
K+E L ++G GAYG V K R +IVA+KK K + + + +T+RE+ +LR L
Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETH-EIVAIKKFKDSEENEEVKETTLRELKMLRTL--- 67
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
+ NIV L + ++ L+LVFE+VE+++ L P +P +++S + +
Sbjct: 68 KQENIVELKEAFR--------RRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQL 119
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV--EMKLTSVVVTLWYRP 205
I + + H + IVHRD+KP NLL++ +KL DFG A+ T V T WYR
Sbjct: 120 IKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRS 179
Query: 206 PEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE+LLGA Y ++D+WS GC+L +L +PL PG S+ DQL I
Sbjct: 180 PELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTI 223
>AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated
kinase 8 delta protein.
Length = 254
Score = 153 bits (370), Expect = 8e-37
Identities = 93/227 (40%), Positives = 132/227 (58%), Gaps = 17/227 (7%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G GAYG V+KA D G ++VA+KK+ A + T REI LL++ HPNI+
Sbjct: 19 LGQGAYGIVWKAVDRRTG-EVVAIKKIFDAFRDKTDAQRTFREITLLQEFGD--HPNIIS 75
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV E D+ + +LVFE ++ DL++ + R G L + R+RS+ + ++ FL
Sbjct: 76 LLDVIRA----ENDRDI--YLVFEFMDTDLNAVI-RKGGLLQDVRVRSIFYQLLRATRFL 128
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DV-----EMKLTSVVVTLWYRPPEV 208
HS +VHRD KP N+L+ VKL DFGLA++ D+ + +T V T WYR PEV
Sbjct: 129 HSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEV 188
Query: 209 LLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRSGP 254
LL + RY +D+WS GC+L ++ RPL PG S QL I + P
Sbjct: 189 LLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIP 235
>AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein.
Length = 640
Score = 151 bits (367), Expect = 2e-36
Identities = 86/233 (36%), Positives = 133/233 (57%), Gaps = 15/233 (6%)
Query: 19 VSALFQNAQ-KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVRE 77
VS L ++ +Y + +G G YG+V R + +G +++A+KK+K +RE
Sbjct: 1 VSGLSRHTMNRYTTIRQLGDGTYGSVLLGRSIESG-ELIAIKKMKRKFYS-WEECMNLRE 58
Query: 78 IALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPE 137
+ L++L H N+V+L +V E D L+ +FE+++++L + PE
Sbjct: 59 VKSLKKLN---HANVVKLKEVIR-----ENDH---LYFIFEYMKENLYQLIKERNKLFPE 107
Query: 138 SRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSV 197
S IR++ + I+ G+ F+H H HRDLKP NLL VK+ADFGLA+ + T
Sbjct: 108 SAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDY 167
Query: 198 VVTLWYRPPEVLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PEVLL Y S +DVW+ GC++A+++T RPL PGAS+ D + +I
Sbjct: 168 VSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKI 220
>BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein.
Length = 292
Score = 151 bits (366), Expect = 2e-36
Identities = 83/223 (37%), Positives = 128/223 (57%), Gaps = 14/223 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
+Y + +G G YG+V R + +G +++A+KK+K +RE+ L++L
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESG-ELIAIKKMKRKFYS-WEECMNLREVKSLKKLN-- 58
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
H N+V+L +V E D L+ +FE+++++L + PES IR++ + I
Sbjct: 59 -HANVVKLKEVIR-----ENDH---LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQI 109
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPE 207
+ G+ F+H H HRDLKP NLL VK+ADFGLA+ + T V T WYR PE
Sbjct: 110 LQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPE 169
Query: 208 VLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
VLL Y S +DVW+ GC++A+++T RPL PGAS+ D + +I
Sbjct: 170 VLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKI 212
>AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein.
Length = 632
Score = 151 bits (366), Expect = 2e-36
Identities = 83/223 (37%), Positives = 128/223 (57%), Gaps = 14/223 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
+Y + +G G YG+V R + +G +++A+KK+K +RE+ L++L
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESG-ELIAIKKMKRKFYS-WEECMNLREVKSLKKLN-- 58
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
H N+V+L +V E D L+ +FE+++++L + PES IR++ + I
Sbjct: 59 -HANVVKLKEVIR-----ENDH---LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQI 109
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPE 207
+ G+ F+H H HRDLKP NLL VK+ADFGLA+ + T V T WYR PE
Sbjct: 110 LQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPE 169
Query: 208 VLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
VLL Y S +DVW+ GC++A+++T RPL PGAS+ D + +I
Sbjct: 170 VLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKI 212
>AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein.
Length = 632
Score = 151 bits (366), Expect = 2e-36
Identities = 83/223 (37%), Positives = 128/223 (57%), Gaps = 14/223 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
+Y + +G G YG+V R + +G +++A+KK+K +RE+ L++L
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESG-ELIAIKKMKRKFYS-WEECMNLREVKSLKKLN-- 58
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
H N+V+L +V E D L+ +FE+++++L + PES IR++ + I
Sbjct: 59 -HANVVKLKEVIR-----ENDH---LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQI 109
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPE 207
+ G+ F+H H HRDLKP NLL VK+ADFGLA+ + T V T WYR PE
Sbjct: 110 LQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPE 169
Query: 208 VLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
VLL Y S +DVW+ GC++A+++T RPL PGAS+ D + +I
Sbjct: 170 VLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKI 212
>AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase
protein.
Length = 632
Score = 151 bits (366), Expect = 2e-36
Identities = 83/223 (37%), Positives = 128/223 (57%), Gaps = 14/223 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
+Y + +G G YG+V R + +G +++A+KK+K +RE+ L++L
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESG-ELIAIKKMKRKFYS-WEECMNLREVKSLKKLN-- 58
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
H N+V+L +V E D L+ +FE+++++L + PES IR++ + I
Sbjct: 59 -HANVVKLKEVIR-----ENDH---LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQI 109
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPE 207
+ G+ F+H H HRDLKP NLL VK+ADFGLA+ + T V T WYR PE
Sbjct: 110 LQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPE 169
Query: 208 VLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
VLL Y S +DVW+ GC++A+++T RPL PGAS+ D + +I
Sbjct: 170 VLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKI 212
>AY065978-1|AAL40897.1| 544|Homo sapiens extracellular
signal-regulated kinase 8 protein.
Length = 544
Score = 151 bits (365), Expect = 3e-36
Identities = 92/227 (40%), Positives = 131/227 (57%), Gaps = 17/227 (7%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G GAYG V+KA D G ++VA+KK+ A + T REI LL++ HPNI+
Sbjct: 19 LGQGAYGIVWKAVDRRTG-EVVAIKKIFDAFRDKTDAQRTFREITLLQEFGD--HPNIIS 75
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV E D+ + +LVFE ++ DL++ + R G L + +RS+ + ++ FL
Sbjct: 76 LLDVIRA----ENDRDI--YLVFEFMDTDLNAVI-RKGGLLQDVHVRSIFYQLLRATRFL 128
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DV-----EMKLTSVVVTLWYRPPEV 208
HS +VHRD KP N+L+ VKL DFGLA++ D+ + +T V T WYR PEV
Sbjct: 129 HSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEV 188
Query: 209 LLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRSGP 254
LL + RY +D+WS GC+L ++ RPL PG S QL I + P
Sbjct: 189 LLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIP 235
>AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase
protein.
Length = 632
Score = 145 bits (352), Expect = 1e-34
Identities = 82/223 (36%), Positives = 128/223 (57%), Gaps = 14/223 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
+Y + +G G YG+V R + +G +++A+KK+K ++ RE+ L++L
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESG-ELIAIKKMKRKFYSWEECMNQ-REVKSLKKLN-- 58
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
H N+V+L +V E D L+ +FE+++++L + PES IR++ + I
Sbjct: 59 -HANVVKLKEVIR-----ENDH---LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQI 109
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPE 207
+ G+ F+H HRDLKP NLL VK+ADFGLA+ + T V T WYR PE
Sbjct: 110 LQGLAFIHKLGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPE 169
Query: 208 VLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
VLL Y S +DVW+ GC++A+++T RPL PGAS+ D + +I
Sbjct: 170 VLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKI 212
>BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein.
Length = 592
Score = 145 bits (351), Expect = 2e-34
Identities = 84/225 (37%), Positives = 123/225 (54%), Gaps = 15/225 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ YE L +G G+YGTV K + N GQIVA+K + E + +REI L+Q
Sbjct: 2 EMYETLGKVGEGSYGTVMKCKH-KNTGQIVAIK-IFYERPEQSVNKIAMREIKFLKQ--- 56
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+ H N+V L++V Q+ + LVFE ++ + L L R+R
Sbjct: 57 FHHENLVNLIEVFR--------QKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQ 108
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWYRP 205
I+ +D+LHS+ I+HRD+KP N+LV+ +G KL DFG A+T + T V T WYR
Sbjct: 109 ILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRA 168
Query: 206 PE-VLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE VL Y +D+W+ GC++ ++ T P LP +SD D LH+I
Sbjct: 169 PELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKI 213
>AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protein
kinase NKIAMRE protein.
Length = 455
Score = 145 bits (351), Expect = 2e-34
Identities = 84/225 (37%), Positives = 123/225 (54%), Gaps = 15/225 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ YE L +G G+YGTV K + N GQIVA+K + E + +REI L+Q
Sbjct: 2 EMYETLGKVGEGSYGTVMKCKH-KNTGQIVAIK-IFYERPEQSVNKIAMREIKFLKQ--- 56
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+ H N+V L++V Q+ + LVFE ++ + L L R+R
Sbjct: 57 FHHENLVNLIEVFR--------QKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQ 108
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL-TSVVVTLWYRP 205
I+ +D+LHS+ I+HRD+KP N+LV+ +G KL DFG A+T + T V T WYR
Sbjct: 109 ILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRA 168
Query: 206 PE-VLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
PE VL Y +D+W+ GC++ ++ T P LP +SD D LH+I
Sbjct: 169 PELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKI 213
>AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein.
Length = 264
Score = 141 bits (341), Expect = 2e-33
Identities = 74/175 (42%), Positives = 114/175 (65%), Gaps = 13/175 (7%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
+ +++++ IG G YG VYKAR+ + GQ+VA+KK+++ +G+P + +REI+LL++L
Sbjct: 2 ENFQKVAQIGQGTYGVVYKARN-KSTGQMVALKKIRLDTETEGVPSTAIREISLLKELN- 59
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFL-SRAPGPLPESRIRSMSH 145
HPNIV+LLDV H + L+LVFE + QDL F+ + A +P I+S
Sbjct: 60 --HPNIVKLLDVIH--------TENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLF 109
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVT 200
++ G+ F HSHR++HRDLKP NLL+ G +KLADFGLA+ + V ++ + VT
Sbjct: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVT 164
Score = 31.5 bits (68), Expect = 3.0
Identities = 14/21 (66%), Positives = 16/21 (76%)
Query: 232 TRRPLLPGASDSDQLHRIFRS 252
TRR L PG S+ DQL RIFR+
Sbjct: 164 TRRALFPGDSEIDQLFRIFRT 184
>U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein.
Length = 297
Score = 140 bits (339), Expect = 4e-33
Identities = 84/231 (36%), Positives = 129/231 (55%), Gaps = 11/231 (4%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+++ ++Y+ LS +G+GAYG+V A D G + VA+KK+ T RE+ LL
Sbjct: 17 IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLR-VAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ + +H N++ LLDV + LE + +LV + DL++ + L + ++
Sbjct: 76 KHM---KHENVIGLLDVFTPARSLEEFNDV--YLVTHLMGADLNNIVKCQK--LTDDHVQ 128
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201
+ + I+ G+ ++HS I+HRDLKP NL V +K+ DFGLA+ D EM T V T
Sbjct: 129 FLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM--TGYVATR 186
Query: 202 WYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYR PE++L Y +D+WS GC++A+L T R L PG DQL I R
Sbjct: 187 WYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR 237
>L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein
protein.
Length = 360
Score = 140 bits (339), Expect = 4e-33
Identities = 84/231 (36%), Positives = 129/231 (55%), Gaps = 11/231 (4%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+++ ++Y+ LS +G+GAYG+V A D G + VA+KK+ T RE+ LL
Sbjct: 17 IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLR-VAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ + +H N++ LLDV + LE + +LV + DL++ + L + ++
Sbjct: 76 KHM---KHENVIGLLDVFTPARSLEEFNDV--YLVTHLMGADLNNIVKCQK--LTDDHVQ 128
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201
+ + I+ G+ ++HS I+HRDLKP NL V +K+ DFGLA+ D EM T V T
Sbjct: 129 FLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM--TGYVATR 186
Query: 202 WYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYR PE++L Y +D+WS GC++A+L T R L PG DQL I R
Sbjct: 187 WYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR 237
>L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein.
Length = 360
Score = 140 bits (339), Expect = 4e-33
Identities = 84/231 (36%), Positives = 129/231 (55%), Gaps = 11/231 (4%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+++ ++Y+ LS +G+GAYG+V A D G + VA+KK+ T RE+ LL
Sbjct: 17 IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLR-VAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ + +H N++ LLDV + LE + +LV + DL++ + L + ++
Sbjct: 76 KHM---KHENVIGLLDVFTPARSLEEFNDV--YLVTHLMGADLNNIVKCQK--LTDDHVQ 128
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201
+ + I+ G+ ++HS I+HRDLKP NL V +K+ DFGLA+ D EM T V T
Sbjct: 129 FLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM--TGYVATR 186
Query: 202 WYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYR PE++L Y +D+WS GC++A+L T R L PG DQL I R
Sbjct: 187 WYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR 237
>CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein.
Length = 360
Score = 140 bits (339), Expect = 4e-33
Identities = 84/231 (36%), Positives = 129/231 (55%), Gaps = 11/231 (4%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+++ ++Y+ LS +G+GAYG+V A D G + VA+KK+ T RE+ LL
Sbjct: 17 IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLR-VAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ + +H N++ LLDV + LE + +LV + DL++ + L + ++
Sbjct: 76 KHM---KHENVIGLLDVFTPARSLEEFNDV--YLVTHLMGADLNNIVKCQK--LTDDHVQ 128
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201
+ + I+ G+ ++HS I+HRDLKP NL V +K+ DFGLA+ D EM T V T
Sbjct: 129 FLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM--TGYVATR 186
Query: 202 WYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYR PE++L Y +D+WS GC++A+L T R L PG DQL I R
Sbjct: 187 WYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR 237
>BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 140 bits (339), Expect = 4e-33
Identities = 84/231 (36%), Positives = 129/231 (55%), Gaps = 11/231 (4%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+++ ++Y+ LS +G+GAYG+V A D G + VA+KK+ T RE+ LL
Sbjct: 17 IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLR-VAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ + +H N++ LLDV + LE + +LV + DL++ + L + ++
Sbjct: 76 KHM---KHENVIGLLDVFTPARSLEEFNDV--YLVTHLMGADLNNIVKCQK--LTDDHVQ 128
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201
+ + I+ G+ ++HS I+HRDLKP NL V +K+ DFGLA+ D EM T V T
Sbjct: 129 FLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM--TGYVATR 186
Query: 202 WYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYR PE++L Y +D+WS GC++A+L T R L PG DQL I R
Sbjct: 187 WYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR 237
>BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 140 bits (339), Expect = 4e-33
Identities = 84/231 (36%), Positives = 129/231 (55%), Gaps = 11/231 (4%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+++ ++Y+ LS +G+GAYG+V A D G + VA+KK+ T RE+ LL
Sbjct: 17 IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLR-VAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ + +H N++ LLDV + LE + +LV + DL++ + L + ++
Sbjct: 76 KHM---KHENVIGLLDVFTPARSLEEFNDV--YLVTHLMGADLNNIVKCQK--LTDDHVQ 128
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201
+ + I+ G+ ++HS I+HRDLKP NL V +K+ DFGLA+ D EM T V T
Sbjct: 129 FLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM--TGYVATR 186
Query: 202 WYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYR PE++L Y +D+WS GC++A+L T R L PG DQL I R
Sbjct: 187 WYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR 237
>BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 140 bits (339), Expect = 4e-33
Identities = 84/231 (36%), Positives = 129/231 (55%), Gaps = 11/231 (4%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+++ ++Y+ LS +G+GAYG+V A D G + VA+KK+ T RE+ LL
Sbjct: 17 IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLR-VAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ + +H N++ LLDV + LE + +LV + DL++ + L + ++
Sbjct: 76 KHM---KHENVIGLLDVFTPARSLEEFNDV--YLVTHLMGADLNNIVKCQK--LTDDHVQ 128
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201
+ + I+ G+ ++HS I+HRDLKP NL V +K+ DFGLA+ D EM T V T
Sbjct: 129 FLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM--TGYVATR 186
Query: 202 WYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYR PE++L Y +D+WS GC++A+L T R L PG DQL I R
Sbjct: 187 WYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR 237
>AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protein
kinase 2a protein.
Length = 360
Score = 140 bits (339), Expect = 4e-33
Identities = 84/231 (36%), Positives = 129/231 (55%), Gaps = 11/231 (4%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+++ ++Y+ LS +G+GAYG+V A D G + VA+KK+ T RE+ LL
Sbjct: 17 IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLR-VAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ + +H N++ LLDV + LE + +LV + DL++ + L + ++
Sbjct: 76 KHM---KHENVIGLLDVFTPARSLEEFNDV--YLVTHLMGADLNNIVKCQK--LTDDHVQ 128
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201
+ + I+ G+ ++HS I+HRDLKP NL V +K+ DFGLA+ D EM T V T
Sbjct: 129 FLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM--TGYVATR 186
Query: 202 WYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYR PE++L Y +D+WS GC++A+L T R L PG DQL I R
Sbjct: 187 WYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR 237
>AB074150-1|BAB85654.1| 307|Homo sapiens Alternative spliced
variant of p38alpha EXIP protein.
Length = 307
Score = 140 bits (339), Expect = 4e-33
Identities = 84/231 (36%), Positives = 129/231 (55%), Gaps = 11/231 (4%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+++ ++Y+ LS +G+GAYG+V A D G + VA+KK+ T RE+ LL
Sbjct: 17 IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLR-VAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ + +H N++ LLDV + LE + +LV + DL++ + L + ++
Sbjct: 76 KHM---KHENVIGLLDVFTPARSLEEFNDV--YLVTHLMGADLNNIVKCQK--LTDDHVQ 128
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201
+ + I+ G+ ++HS I+HRDLKP NL V +K+ DFGLA+ D EM T V T
Sbjct: 129 FLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM--TGYVATR 186
Query: 202 WYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYR PE++L Y +D+WS GC++A+L T R L PG DQL I R
Sbjct: 187 WYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR 237
>Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein
kinase-3 protein.
Length = 367
Score = 140 bits (338), Expect = 6e-33
Identities = 83/224 (37%), Positives = 122/224 (54%), Gaps = 11/224 (4%)
Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88
Y +L +G+GAYG V A D G + VA+KK+ + RE+ LL+ + R
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAK-VAIKKLYRPFQSELFAKRAYRELRLLKHM---R 82
Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148
H N++ LLDV + L D +LV + DL + L E RI+ + + ++
Sbjct: 83 HENVIGLLDVFTPDETL--DDFTDFYLVMPFMGTDLGKLMKHEK--LGEDRIQFLVYQML 138
Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEV 208
G+ ++H+ I+HRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV
Sbjct: 139 KGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEM--TGYVVTRWYRAPEV 196
Query: 209 LLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
+L RY +D+WS GC++A++ T + L G+ DQL I +
Sbjct: 197 ILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK 240
>U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein.
Length = 367
Score = 140 bits (338), Expect = 6e-33
Identities = 83/224 (37%), Positives = 122/224 (54%), Gaps = 11/224 (4%)
Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88
Y +L +G+GAYG V A D G + VA+KK+ + RE+ LL+ + R
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAK-VAIKKLYRPFQSELFAKRAYRELRLLKHM---R 82
Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148
H N++ LLDV + L D +LV + DL + L E RI+ + + ++
Sbjct: 83 HENVIGLLDVFTPDETL--DDFTDFYLVMPFMGTDLGKLMKHEK--LGEDRIQFLVYQML 138
Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEV 208
G+ ++H+ I+HRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV
Sbjct: 139 KGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEM--TGYVVTRWYRAPEV 196
Query: 209 LLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
+L RY +D+WS GC++A++ T + L G+ DQL I +
Sbjct: 197 ILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK 240
>L35263-1|AAA57455.1| 360|Homo sapiens CSaids binding protein
protein.
Length = 360
Score = 140 bits (338), Expect = 6e-33
Identities = 83/231 (35%), Positives = 130/231 (56%), Gaps = 11/231 (4%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+++ ++Y+ LS +G+GAYG+V A D G + VA+KK+ T RE+ LL
Sbjct: 17 IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLR-VAVKKLSRPFQSIIHAKRTYRELRLL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ + +H N++ LLDV + LE + +LV + DL++ + L + ++
Sbjct: 76 KHM---KHENVIGLLDVFTPARSLEEFNDV--YLVTHLMGADLNNIVKCQK--LTDDHVQ 128
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTL 201
+ + I+ G+ ++HS I+HRDLKP NL V +K+ DFGLA+ D EM T V T
Sbjct: 129 FLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM--TGYVATR 186
Query: 202 WYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
WYR PE++L Y +D+WS GC++A+L T R L PG +QL +I R
Sbjct: 187 WYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMR 237
>BC039825-1|AAH39825.1| 457|Homo sapiens MAK protein protein.
Length = 457
Score = 140 bits (338), Expect = 6e-33
Identities = 78/223 (34%), Positives = 128/223 (57%), Gaps = 14/223 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
+Y + +G G YG+V + + G++VA+K++K ++ +RE+ L++L
Sbjct: 3 RYTTMRQLGDGTYGSVLMGKS-NESGELVAIKRMKRKFYSWDECMN-LREVKSLKKLN-- 58
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
H N+++L +V E D L+ +FE+++++L + PES IR++ + I
Sbjct: 59 -HANVIKLKEVIR-----ENDH---LYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQI 109
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPE 207
+ G+ F+H H HRD+KP NLL VK+ADFGLA+ + T V T WYR PE
Sbjct: 110 LQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPE 169
Query: 208 VLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
VLL + Y S +DVW+ G ++A+L+ RPL PG S+ D++ +I
Sbjct: 170 VLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKI 212
>BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated protein
kinase 12 protein.
Length = 367
Score = 140 bits (338), Expect = 6e-33
Identities = 83/224 (37%), Positives = 122/224 (54%), Gaps = 11/224 (4%)
Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88
Y +L +G+GAYG V A D G + VA+KK+ + RE+ LL+ + R
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAK-VAIKKLYRPFQSELFAKRAYRELRLLKHM---R 82
Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148
H N++ LLDV + L D +LV + DL + L E RI+ + + ++
Sbjct: 83 HENVIGLLDVFTPDETL--DDFTDFYLVMPFMGTDLGKLMKHEK--LGEDRIQFLVYQML 138
Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEV 208
G+ ++H+ I+HRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV
Sbjct: 139 KGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEM--TGYVVTRWYRAPEV 196
Query: 209 LLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
+L RY +D+WS GC++A++ T + L G+ DQL I +
Sbjct: 197 ILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK 240
>AL024498-4|CAB75823.1| 623|Homo sapiens protein ( Human DNA
sequence from clone RP3-417M14 on chromosome 6p23-25.1.
).
Length = 623
Score = 140 bits (338), Expect = 6e-33
Identities = 78/223 (34%), Positives = 128/223 (57%), Gaps = 14/223 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
+Y + +G G YG+V + + G++VA+K++K ++ +RE+ L++L
Sbjct: 3 RYTTMRQLGDGTYGSVLMGKS-NESGELVAIKRMKRKFYSWDECMN-LREVKSLKKLN-- 58
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
H N+++L +V E D L+ +FE+++++L + PES IR++ + I
Sbjct: 59 -HANVIKLKEVIR-----ENDH---LYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQI 109
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPE 207
+ G+ F+H H HRD+KP NLL VK+ADFGLA+ + T V T WYR PE
Sbjct: 110 LQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPE 169
Query: 208 VLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
VLL + Y S +DVW+ G ++A+L+ RPL PG S+ D++ +I
Sbjct: 170 VLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKI 212
>AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated protein
kinase 12 protein.
Length = 367
Score = 140 bits (338), Expect = 6e-33
Identities = 83/224 (37%), Positives = 122/224 (54%), Gaps = 11/224 (4%)
Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88
Y +L +G+GAYG V A D G + VA+KK+ + RE+ LL+ + R
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAK-VAIKKLYRPFQSELFAKRAYRELRLLKHM---R 82
Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148
H N++ LLDV + L D +LV + DL + L E RI+ + + ++
Sbjct: 83 HENVIGLLDVFTPDETL--DDFTDFYLVMPFMGTDLGKLMKHEK--LGEDRIQFLVYQML 138
Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEV 208
G+ ++H+ I+HRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV
Sbjct: 139 KGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEM--TGYVVTRWYRAPEV 196
Query: 209 LLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
+L RY +D+WS GC++A++ T + L G+ DQL I +
Sbjct: 197 ILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK 240
>AF505623-1|AAN16405.1| 623|Homo sapiens male germ cell-associated
kinase protein.
Length = 623
Score = 140 bits (338), Expect = 6e-33
Identities = 78/223 (34%), Positives = 128/223 (57%), Gaps = 14/223 (6%)
Query: 28 KYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAY 87
+Y + +G G YG+V + + G++VA+K++K ++ +RE+ L++L
Sbjct: 3 RYTTMRQLGDGTYGSVLMGKS-NESGELVAIKRMKRKFYSWDECMN-LREVKSLKKLN-- 58
Query: 88 RHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDI 147
H N+++L +V E D L+ +FE+++++L + PES IR++ + I
Sbjct: 59 -HANVIKLKEVIR-----ENDH---LYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQI 109
Query: 148 ISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPE 207
+ G+ F+H H HRD+KP NLL VK+ADFGLA+ + T V T WYR PE
Sbjct: 110 LQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPE 169
Query: 208 VLL-GARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
VLL + Y S +DVW+ G ++A+L+ RPL PG S+ D++ +I
Sbjct: 170 VLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKI 212
>Z84480-1|CAI20520.1| 502|Homo sapiens cell division cycle 2-like 6
(CDK8-like) protein.
Length = 502
Score = 138 bits (333), Expect = 2e-32
Identities = 87/220 (39%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKARDLHNGGQI-VAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKAR + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V L + V +L+F++ E DL S ++ P LP S ++S+ +
Sbjct: 80 ALQKVF-----LSHSDRKV-WLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>BC037289-1|AAH37289.1| 502|Homo sapiens CDC2L6 protein protein.
Length = 502
Score = 138 bits (333), Expect = 2e-32
Identities = 87/220 (39%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKARDLHNGGQI-VAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKAR + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V L + V +L+F++ E DL S ++ P LP S ++S+ +
Sbjct: 80 ALQKVF-----LSHSDRKV-WLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>AY028424-1|AAK27731.1| 502|Homo sapiens death-preventing kinase
protein.
Length = 502
Score = 138 bits (333), Expect = 2e-32
Identities = 87/220 (39%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKARDLHNGGQI-VAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKAR + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V L + V +L+F++ E DL S ++ P LP S ++S+ +
Sbjct: 80 ALQKVF-----LSHSDRKV-WLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>AL603914-4|CAI41175.1| 502|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 502
Score = 138 bits (333), Expect = 2e-32
Identities = 87/220 (39%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKARDLHNGGQI-VAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKAR + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V L + V +L+F++ E DL S ++ P LP S ++S+ +
Sbjct: 80 ALQKVF-----LSHSDRKV-WLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>AL512430-4|CAI40286.1| 502|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 502
Score = 138 bits (333), Expect = 2e-32
Identities = 87/220 (39%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKARDLHNGGQI-VAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKAR + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V L + V +L+F++ E DL S ++ P LP S ++S+ +
Sbjct: 80 ALQKVF-----LSHSDRKV-WLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>AK131512-1|BAD18656.1| 345|Homo sapiens protein ( Homo sapiens
cDNA FLJ16732 fis, clone BNGH42005017, moderately
similar to SERINE/THREONINE-PROTEIN KINASE PCTAIRE-1 (EC
2.7.1.-). ).
Length = 345
Score = 138 bits (333), Expect = 2e-32
Identities = 88/231 (38%), Positives = 128/231 (55%), Gaps = 37/231 (16%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F A Y L +G G+Y TVYK NG Q+VA+K + + E+G+P + +RE +LL+
Sbjct: 97 FGAASSYLNLEKLGEGSYATVYKGISRING-QLVALKVISMN-AEEGVPFTAIREASLLK 154
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
L +H NIV L D+ H + L VFE++ L F
Sbjct: 155 GL---KHANIVLLHDIIHTKETLT--------FVFEYM---LFMF--------------- 185
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV-EMKLTSVVVTL 201
++ G+ ++H ++HRDLKP NLL++ G +KLADFGLA+ + +S VVTL
Sbjct: 186 ---QLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTL 242
Query: 202 WYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASD-SDQLHRIF 250
WYRPP+ LLGA Y S LD+W AGC+ ++ +PL PG S+ +QL +I+
Sbjct: 243 WYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIW 293
>AB028951-1|BAA82980.2| 501|Homo sapiens KIAA1028 protein protein.
Length = 501
Score = 138 bits (333), Expect = 2e-32
Identities = 87/220 (39%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKARDLHNGGQI-VAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKAR + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 26 VGRGTYGHVYKARRKDGKDEKEYALKQIEGT----GISMSACREIALLREL---KHPNVI 78
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V L + V +L+F++ E DL S ++ P LP S ++S+ +
Sbjct: 79 ALQKVF-----LSHSDRKV-WLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLY 132
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 133 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 192
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 193 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 232
>X79483-1|CAA55984.1| 367|Homo sapiens extracellular signal
regulated kinase protein.
Length = 367
Score = 136 bits (330), Expect = 5e-32
Identities = 82/224 (36%), Positives = 121/224 (54%), Gaps = 11/224 (4%)
Query: 29 YEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYR 88
Y +L +G+GAYG V A D G + VA+KK+ + RE+ LL+ + R
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAK-VAIKKLYRPFQSELFAKLAYRELRLLKHM---R 82
Query: 89 HPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDII 148
H N++ LLDV + L D +LV + DL + L E RI+ + + ++
Sbjct: 83 HENVIGLLDVFTPDETL--DDFTDFYLVMPFMGTDLGKLMKHEK--LGEDRIQFLVYQMM 138
Query: 149 SGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEV 208
G+ ++H+ I+HRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV
Sbjct: 139 KGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEM--TGYVVTRWYRAPEV 196
Query: 209 LLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
+L Y +D+WS GC++A++ T + L G+ DQL I +
Sbjct: 197 ILNWIAYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK 240
>BC000281-1|AAH00281.2| 283|Homo sapiens PCTK3 protein protein.
Length = 283
Score = 136 bits (328), Expect = 9e-32
Identities = 69/170 (40%), Positives = 103/170 (60%), Gaps = 10/170 (5%)
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+ +H NIV L D+ H D+ L L VFE+++ DL +L + ++
Sbjct: 3 LKNLKHANIVTLHDLIH------TDRSLTL--VFEYLDSDLKQYLDHCGNLMSMHNVKIF 54
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK-LTSVVVTLW 202
++ G+ + H +I+HRDLKP NLL+ G +KLADFGLA+ V K ++ VVTLW
Sbjct: 55 MFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLW 114
Query: 203 YRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
YRPP+VLLG+ Y + +D+W GC+ ++ T RPL PG++ ++LH IFR
Sbjct: 115 YRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFR 164
>X85753-1|CAA59754.1| 464|Homo sapiens CDK8 protein kinase protein.
Length = 464
Score = 134 bits (325), Expect = 2e-31
Identities = 85/220 (38%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKA-RDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKA R + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V D+++ +L+F++ E DL S ++ P LP ++S+ +
Sbjct: 80 SLQKVFLS----HADRKV--WLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>BC107601-1|AAI07602.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 134 bits (325), Expect = 2e-31
Identities = 85/220 (38%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKA-RDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKA R + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V D+++ +L+F++ E DL S ++ P LP ++S+ +
Sbjct: 80 SLQKVFLS----HADRKV--WLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>BC105950-1|AAI05951.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 134 bits (325), Expect = 2e-31
Identities = 85/220 (38%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKA-RDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKA R + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V D+++ +L+F++ E DL S ++ P LP ++S+ +
Sbjct: 80 SLQKVFLS----HADRKV--WLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>BC104492-1|AAI04493.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 134 bits (325), Expect = 2e-31
Identities = 85/220 (38%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKA-RDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKA R + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V D+++ +L+F++ E DL S ++ P LP ++S+ +
Sbjct: 80 SLQKVFLS----HADRKV--WLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>BC069634-1|AAH69634.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 134 bits (325), Expect = 2e-31
Identities = 85/220 (38%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKA-RDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKA R + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V D+++ +L+F++ E DL S ++ P LP ++S+ +
Sbjct: 80 SLQKVFLS----HADRKV--WLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>AL590108-1|CAH72300.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 134 bits (325), Expect = 2e-31
Identities = 85/220 (38%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKA-RDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKA R + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V D+++ +L+F++ E DL S ++ P LP ++S+ +
Sbjct: 80 SLQKVFLS----HADRKV--WLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>AL159159-1|CAI16960.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 134 bits (325), Expect = 2e-31
Identities = 85/220 (38%), Positives = 129/220 (58%), Gaps = 31/220 (14%)
Query: 35 IGTGAYGTVYKA-RDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIV 93
+G G YG VYKA R + A+K+++ GI +S REIALLR+L +HPN++
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGT----GISMSACREIALLREL---KHPNVI 79
Query: 94 RLLDVCHGGQCLERDQQLVLFLVFEHVEQDL--------DSFLSRAPGPLPESRIRSMSH 145
L V D+++ +L+F++ E DL S ++ P LP ++S+ +
Sbjct: 80 SLQKVFLS----HADRKV--WLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLY 133
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKLADFGLAKTYDVEMK----LTSV 197
I+ G+ +LH++ ++HRDLKP N+LV GRVK+AD G A+ ++ +K L V
Sbjct: 134 QILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPV 193
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPL 236
VVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T P+
Sbjct: 194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 233
>Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein.
Length = 360
Score = 134 bits (323), Expect = 4e-31
Identities = 83/233 (35%), Positives = 126/233 (54%), Gaps = 15/233 (6%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+F +Y LS IG GAYG V A D N + VA+KK+ T+REI +L
Sbjct: 18 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR-VAIKKIS-PFEHQTYCQRTLREIKIL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ +RH NI+ + D+ Q +Q +++V + +E DL L L I
Sbjct: 76 LR---FRHENIIGINDII---QAPTIEQMKDVYIVQDLMETDLYKLLKTQH--LSNDHIC 127
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSV 197
+ I+ G+ ++HS ++HRDLKP NLL+ +K+ DFGLA+ D + LT
Sbjct: 128 YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEY 187
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 188 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 240
>Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase
protein.
Length = 355
Score = 133 bits (322), Expect = 5e-31
Identities = 82/232 (35%), Positives = 124/232 (53%), Gaps = 15/232 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +Y +L IG GAYG V A D H VA+KK+ T+REI +L
Sbjct: 12 FDVGPRYTQLQYIGEGAYGMVSSAYD-HVRKTRVAIKKIS-PFEHQTYCQRTLREIQILL 69
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+ +RH N++ + D+ LE + + ++V + +E DL L L I
Sbjct: 70 R---FRHENVIGIRDILRAST-LEAMRDV--YIVQDLMETDLYKLLKSQQ--LSNDHICY 121
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSVV 198
+ I+ G+ ++HS ++HRDLKP NLL+ +K+ DFGLA+ D E LT V
Sbjct: 122 FLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYV 181
Query: 199 VTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 182 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 233
>M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein.
Length = 366
Score = 133 bits (322), Expect = 5e-31
Identities = 82/232 (35%), Positives = 124/232 (53%), Gaps = 15/232 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +Y +L IG GAYG V A D H VA+KK+ T+REI +L
Sbjct: 23 FDVGPRYTQLQYIGEGAYGMVSSAYD-HVRKTRVAIKKIS-PFEHQTYCQRTLREIQILL 80
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+ +RH N++ + D+ LE + + ++V + +E DL L L I
Sbjct: 81 R---FRHENVIGIRDILRAST-LEAMRDV--YIVQDLMETDLYKLLKSQQ--LSNDHICY 132
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSVV 198
+ I+ G+ ++HS ++HRDLKP NLL+ +K+ DFGLA+ D E LT V
Sbjct: 133 FLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYV 192
Query: 199 VTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 193 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 244
>BC028034-1|AAH28034.1| 277|Homo sapiens MAPK15 protein protein.
Length = 277
Score = 133 bits (322), Expect = 5e-31
Identities = 92/244 (37%), Positives = 131/244 (53%), Gaps = 34/244 (13%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G GAYG V+KA D G ++VA+KK+ A + T REI LL++ HPNI+
Sbjct: 19 LGQGAYGIVWKAVDRRTG-EVVAIKKIFDAFRDKTDAQRTFREITLLQEFGD--HPNIIS 75
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHV-----------------EQDLDSFLSRAPGPLPE 137
LLDV E D+ + +LVFE + + DL++ + R G L +
Sbjct: 76 LLDVIRA----ENDRDI--YLVFEFMGCPPSPPPPTAVRTLSADTDLNAVI-RKGGLLQD 128
Query: 138 SRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTY-DV-----E 191
+RS+ + ++ FLHS +VHRD KP N+L+ VKL DFGLA++ D+ +
Sbjct: 129 VHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPED 188
Query: 192 MKLTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
+T V T WYR PEVLL + RY +D+WS GC+L ++ RPL PG S QL I
Sbjct: 189 QAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELIL 248
Query: 251 RSGP 254
+ P
Sbjct: 249 ETIP 252
>BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated protein
kinase 3 protein.
Length = 379
Score = 133 bits (322), Expect = 5e-31
Identities = 82/232 (35%), Positives = 124/232 (53%), Gaps = 15/232 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +Y +L IG GAYG V A D H VA+KK+ T+REI +L
Sbjct: 36 FDVGPRYTQLQYIGEGAYGMVSSAYD-HVRKTRVAIKKIS-PFEHQTYCQRTLREIQILL 93
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+ +RH N++ + D+ LE + + ++V + +E DL L L I
Sbjct: 94 R---FRHENVIGIRDILRAST-LEAMRDV--YIVQDLMETDLYKLLKSQQ--LSNDHICY 145
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSVV 198
+ I+ G+ ++HS ++HRDLKP NLL+ +K+ DFGLA+ D E LT V
Sbjct: 146 FLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYV 205
Query: 199 VTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 206 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 257
>Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase
protein.
Length = 348
Score = 133 bits (321), Expect = 7e-31
Identities = 82/233 (35%), Positives = 125/233 (53%), Gaps = 15/233 (6%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+F +Y LS IG GAYG V A D N + VA+KK+ T+REI +L
Sbjct: 6 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR-VAIKKIS-PFEHQTYCQRTLREIKIL 63
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ +RH NI+ + D+ +Q +++V + +E DL L L I
Sbjct: 64 LR---FRHENIIGINDIIRAPTI---EQMKDVYIVQDLMETDLYKLLKTQH--LSNDHIC 115
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSV 197
+ I+ G+ ++HS ++HRDLKP NLL+ +K+ DFGLA+ D + LT
Sbjct: 116 YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEY 175
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 176 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 228
>M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein.
Length = 360
Score = 133 bits (321), Expect = 7e-31
Identities = 82/233 (35%), Positives = 125/233 (53%), Gaps = 15/233 (6%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+F +Y LS IG GAYG V A D N + VA+KK+ T+REI +L
Sbjct: 18 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR-VAIKKIS-PFEHQTYCQRTLREIKIL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ +RH NI+ + D+ +Q +++V + +E DL L L I
Sbjct: 76 LR---FRHENIIGINDIIRAPTI---EQMKDVYIVQDLMETDLYKLLKTQH--LSNDHIC 127
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSV 197
+ I+ G+ ++HS ++HRDLKP NLL+ +K+ DFGLA+ D + LT
Sbjct: 128 YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEY 187
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 188 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 240
>DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 133 bits (321), Expect = 7e-31
Identities = 82/233 (35%), Positives = 125/233 (53%), Gaps = 15/233 (6%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+F +Y LS IG GAYG V A D N + VA+KK+ T+REI +L
Sbjct: 18 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR-VAIKKIS-PFEHQTYCQRTLREIKIL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ +RH NI+ + D+ +Q +++V + +E DL L L I
Sbjct: 76 LR---FRHENIIGINDIIRAPTI---EQMKDVYIVQDLMETDLYKLLKTQH--LSNDHIC 127
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSV 197
+ I+ G+ ++HS ++HRDLKP NLL+ +K+ DFGLA+ D + LT
Sbjct: 128 YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEY 187
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 188 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 240
>BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 133 bits (321), Expect = 7e-31
Identities = 82/233 (35%), Positives = 125/233 (53%), Gaps = 15/233 (6%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+F +Y LS IG GAYG V A D N + VA+KK+ T+REI +L
Sbjct: 18 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR-VAIKKIS-PFEHQTYCQRTLREIKIL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ +RH NI+ + D+ +Q +++V + +E DL L L I
Sbjct: 76 LR---FRHENIIGINDIIRAPTI---EQMKDVYIVQDLMETDLYKLLKTQH--LSNDHIC 127
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSV 197
+ I+ G+ ++HS ++HRDLKP NLL+ +K+ DFGLA+ D + LT
Sbjct: 128 YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEY 187
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 188 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 240
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 132 bits (318), Expect = 2e-30
Identities = 79/211 (37%), Positives = 124/211 (58%), Gaps = 16/211 (7%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKV-KVALTEDGIPLSTVREIALLRQLE 85
+KY L +IG G++G VYK R ++ Q+VA+K + K+ +E + + REI ++R L
Sbjct: 2 EKYHVLEMIGEGSFGRVYKGRRKYSA-QVVALKFIPKLGRSEKELR-NLQREIEIMRGL- 58
Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145
RHPNIV +LD E D+++V+ V ++ E +L L G LPE ++++++
Sbjct: 59 --RHPNIVHMLD------SFETDKEVVV--VTDYAEGELFQILED-DGKLPEDQVQAIAA 107
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE-MKLTSVVVTLWYR 204
++S + +LHSHRI+HRD+KP N+L+ G +KL DFG A+ M LTS+ T Y
Sbjct: 108 QLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYM 167
Query: 205 PPEVLLGARYCSALDVWSAGCVLAQLHTRRP 235
PE++ Y D+WS GC+L +L P
Sbjct: 168 SPELVEERPYDHTADLWSVGCILYELAVGTP 198
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 132 bits (318), Expect = 2e-30
Identities = 79/211 (37%), Positives = 124/211 (58%), Gaps = 16/211 (7%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKV-KVALTEDGIPLSTVREIALLRQLE 85
+KY L +IG G++G VYK R ++ Q+VA+K + K+ +E + + REI ++R L
Sbjct: 2 EKYHVLEMIGEGSFGRVYKGRRKYSA-QVVALKFIPKLGRSEKELR-NLQREIEIMRGL- 58
Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145
RHPNIV +LD E D+++V+ V ++ E +L L G LPE ++++++
Sbjct: 59 --RHPNIVHMLD------SFETDKEVVV--VTDYAEGELFQILED-DGKLPEDQVQAIAA 107
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE-MKLTSVVVTLWYR 204
++S + +LHSHRI+HRD+KP N+L+ G +KL DFG A+ M LTS+ T Y
Sbjct: 108 QLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYM 167
Query: 205 PPEVLLGARYCSALDVWSAGCVLAQLHTRRP 235
PE++ Y D+WS GC+L +L P
Sbjct: 168 SPELVEERPYDHTADLWSVGCILYELAVGTP 198
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 132 bits (318), Expect = 2e-30
Identities = 79/211 (37%), Positives = 124/211 (58%), Gaps = 16/211 (7%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKV-KVALTEDGIPLSTVREIALLRQLE 85
+KY L +IG G++G VYK R ++ Q+VA+K + K+ +E + + REI ++R L
Sbjct: 19 EKYHVLEMIGEGSFGRVYKGRRKYSA-QVVALKFIPKLGRSEKELR-NLQREIEIMRGL- 75
Query: 86 AYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH 145
RHPNIV +LD E D+++V+ V ++ E +L L G LPE ++++++
Sbjct: 76 --RHPNIVHMLD------SFETDKEVVV--VTDYAEGELFQILED-DGKLPEDQVQAIAA 124
Query: 146 DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVE-MKLTSVVVTLWYR 204
++S + +LHSHRI+HRD+KP N+L+ G +KL DFG A+ M LTS+ T Y
Sbjct: 125 QLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYM 184
Query: 205 PPEVLLGARYCSALDVWSAGCVLAQLHTRRP 235
PE++ Y D+WS GC+L +L P
Sbjct: 185 SPELVEERPYDHTADLWSVGCILYELAVGTP 215
>X60188-1|CAA42744.1| 379|Homo sapiens protein serine/threonine
kinase protein.
Length = 379
Score = 131 bits (317), Expect = 2e-30
Identities = 82/232 (35%), Positives = 123/232 (53%), Gaps = 15/232 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +Y +L IG GAYG V A D H VA+KK+ T+REI +L
Sbjct: 36 FDVGPRYTQLQYIGEGAYGMVSSAYD-HVRKTRVAIKKIS-PFEHQTYCQRTLREIQILL 93
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+ +RH N++ + D+ LE + + ++V + +E DL L L I
Sbjct: 94 R---FRHENVIGIRDILRAST-LEAMRDV--YIVQDLMETDLYKLLKSQQ--LSNDHICY 145
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSVV 198
+ I+ G+ ++HS ++HRDLKP NLL +K+ DFGLA+ D E LT V
Sbjct: 146 FLYQILRGLKYIHSANVLHRDLKPSNLLSNTTCDLKICDFGLARIADPEHDHTGFLTEYV 205
Query: 199 VTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 206 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 257
>AY033608-1|AAK52330.1| 335|Homo sapiens extracellular
signal-related kinase 1c protein.
Length = 335
Score = 131 bits (317), Expect = 2e-30
Identities = 82/232 (35%), Positives = 123/232 (53%), Gaps = 15/232 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +Y +L IG GAYG V A D H VA+KK+ T+REI +L
Sbjct: 36 FDVGPRYTQLQYIGEGAYGMVSSAYD-HVRKTRVAIKKIS-PFEHQTYCQRTLREIQILL 93
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+ +RH N++ + D+ LE + + ++V + +E DL L L I
Sbjct: 94 R---FRHENVIGIRDILRAST-LEAMRDV--YIVQDLMETDLYKLLKSQQ--LSNDHICY 145
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSVV 198
+ I+ G+ ++HS ++HRDLKP NLL +K+ DFGLA+ D E LT V
Sbjct: 146 FLYQILRGLKYIHSANVLHRDLKPSNLLSNTTCDLKICDFGLARIADPEHDHTGFLTEYV 205
Query: 199 VTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 206 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 257
>AY033607-1|AAK52329.1| 357|Homo sapiens extracellular
signal-related kinase 1b protein.
Length = 357
Score = 131 bits (317), Expect = 2e-30
Identities = 82/232 (35%), Positives = 123/232 (53%), Gaps = 15/232 (6%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +Y +L IG GAYG V A D H VA+KK+ T+REI +L
Sbjct: 36 FDVGPRYTQLQYIGEGAYGMVSSAYD-HVRKTRVAIKKIS-PFEHQTYCQRTLREIQILL 93
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
+ +RH N++ + D+ LE + + ++V + +E DL L L I
Sbjct: 94 R---FRHENVIGIRDILRAST-LEAMRDV--YIVQDLMETDLYKLLKSQQ--LSNDHICY 145
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSVV 198
+ I+ G+ ++HS ++HRDLKP NLL +K+ DFGLA+ D E LT V
Sbjct: 146 FLYQILRGLKYIHSANVLHRDLKPSNLLSNTTCDLKICDFGLARIADPEHDHTGFLTEYV 205
Query: 199 VTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 206 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 257
>AC006036-1|AAF19245.1| 165|Homo sapiens unknown protein.
Length = 165
Score = 131 bits (317), Expect = 2e-30
Identities = 69/170 (40%), Positives = 98/170 (57%), Gaps = 11/170 (6%)
Query: 84 LEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSM 143
L+ +H NIV L D+ H + L LVFE+V DL ++ + PG L ++
Sbjct: 3 LKGLKHANIVLLHDIIHTKETLT--------LVFEYVHTDLCQYMDKHPGGLHPDNVKLF 54
Query: 144 SHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDV-EMKLTSVVVTLW 202
++ G+ ++H I+HRDLKP NLL++ G +KLADFGLA+ V ++ VVTLW
Sbjct: 55 LFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLW 114
Query: 203 YRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASD-SDQLHRIF 250
YRPP+VLLG+ Y + LD+W GC+ ++ PG D DQL RIF
Sbjct: 115 YRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIF 164
>Z95152-3|CAB08438.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 131 bits (316), Expect = 3e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>Y10488-1|CAA71512.1| 365|Homo sapiens stress-activated protein
kinase-4 protein.
Length = 365
Score = 131 bits (316), Expect = 3e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>U93232-1|AAB87639.1| 365|Homo sapiens MAP kinase p38delta protein.
Length = 365
Score = 131 bits (316), Expect = 3e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>CR541687-1|CAG46488.1| 365|Homo sapiens MAPK13 protein.
Length = 365
Score = 131 bits (316), Expect = 3e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>CR536490-1|CAG38729.1| 365|Homo sapiens MAPK13 protein.
Length = 365
Score = 131 bits (316), Expect = 3e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>BT007221-1|AAP35885.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 131 bits (316), Expect = 3e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>BC004428-1|AAH04428.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 131 bits (316), Expect = 3e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>BC001641-1|AAH01641.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 131 bits (316), Expect = 3e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>BC000433-1|AAH00433.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 131 bits (316), Expect = 3e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>AF100546-1|AAF36772.1| 365|Homo sapiens stress-activated protein
kinase 4 protein.
Length = 365
Score = 131 bits (316), Expect = 3e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>AF092535-1|AAD23377.1| 365|Homo sapiens mitogen-activated protein
kinase p38delta protein.
Length = 365
Score = 130 bits (315), Expect = 4e-30
Identities = 77/218 (35%), Positives = 118/218 (54%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFRGKDYLDQLTQILK 237
>U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein.
Length = 816
Score = 130 bits (314), Expect = 5e-30
Identities = 78/233 (33%), Positives = 124/233 (53%), Gaps = 13/233 (5%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +YE + IG GAYG V AR G Q VA+KK+ A T+RE+ +L+
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQ-VAIKKIPNAFDVVTNAKRTLRELKILK 107
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
++H NI+ + D+ + + +++V + +E DL + + PL +R
Sbjct: 108 H---FKHDNIIAIKDILR--PTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRY 161
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK---TYDVEMK--LTSV 197
+ ++ G+ ++HS +++HRDLKP NLLV +K+ DFG+A+ T E + +T
Sbjct: 162 FLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEY 221
Query: 198 VVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L Y A+D+WS GC+ ++ RR L PG + QL I
Sbjct: 222 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLI 274
>U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein.
Length = 816
Score = 130 bits (314), Expect = 5e-30
Identities = 78/233 (33%), Positives = 124/233 (53%), Gaps = 13/233 (5%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +YE + IG GAYG V AR G Q VA+KK+ A T+RE+ +L+
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQ-VAIKKIPNAFDVVTNAKRTLRELKILK 107
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
++H NI+ + D+ + + +++V + +E DL + + PL +R
Sbjct: 108 H---FKHDNIIAIKDILR--PTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRY 161
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK---TYDVEMK--LTSV 197
+ ++ G+ ++HS +++HRDLKP NLLV +K+ DFG+A+ T E + +T
Sbjct: 162 FLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEY 221
Query: 198 VVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L Y A+D+WS GC+ ++ RR L PG + QL I
Sbjct: 222 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLI 274
>U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein.
Length = 816
Score = 130 bits (314), Expect = 5e-30
Identities = 78/233 (33%), Positives = 124/233 (53%), Gaps = 13/233 (5%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +YE + IG GAYG V AR G Q VA+KK+ A T+RE+ +L+
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQ-VAIKKIPNAFDVVTNAKRTLRELKILK 107
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
++H NI+ + D+ + + +++V + +E DL + + PL +R
Sbjct: 108 H---FKHDNIIAIKDILR--PTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRY 161
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK---TYDVEMK--LTSV 197
+ ++ G+ ++HS +++HRDLKP NLLV +K+ DFG+A+ T E + +T
Sbjct: 162 FLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEY 221
Query: 198 VVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L Y A+D+WS GC+ ++ RR L PG + QL I
Sbjct: 222 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLI 274
>U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein.
Length = 815
Score = 130 bits (314), Expect = 5e-30
Identities = 78/233 (33%), Positives = 124/233 (53%), Gaps = 13/233 (5%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +YE + IG GAYG V AR G Q VA+KK+ A T+RE+ +L+
Sbjct: 48 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQ-VAIKKIPNAFDVVTNAKRTLRELKILK 106
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
++H NI+ + D+ + + +++V + +E DL + + PL +R
Sbjct: 107 H---FKHDNIIAIKDILR--PTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRY 160
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK---TYDVEMK--LTSV 197
+ ++ G+ ++HS +++HRDLKP NLLV +K+ DFG+A+ T E + +T
Sbjct: 161 FLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEY 220
Query: 198 VVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L Y A+D+WS GC+ ++ RR L PG + QL I
Sbjct: 221 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLI 273
>BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 816
Score = 130 bits (314), Expect = 5e-30
Identities = 78/233 (33%), Positives = 124/233 (53%), Gaps = 13/233 (5%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +YE + IG GAYG V AR G Q VA+KK+ A T+RE+ +L+
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQ-VAIKKIPNAFDVVTNAKRTLRELKILK 107
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
++H NI+ + D+ + + +++V + +E DL + + PL +R
Sbjct: 108 H---FKHDNIIAIKDILR--PTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRY 161
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK---TYDVEMK--LTSV 197
+ ++ G+ ++HS +++HRDLKP NLLV +K+ DFG+A+ T E + +T
Sbjct: 162 FLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEY 221
Query: 198 VVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L Y A+D+WS GC+ ++ RR L PG + QL I
Sbjct: 222 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLI 274
>BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 816
Score = 130 bits (314), Expect = 5e-30
Identities = 78/233 (33%), Positives = 124/233 (53%), Gaps = 13/233 (5%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +YE + IG GAYG V AR G Q VA+KK+ A T+RE+ +L+
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQ-VAIKKIPNAFDVVTNAKRTLRELKILK 107
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
++H NI+ + D+ + + +++V + +E DL + + PL +R
Sbjct: 108 H---FKHDNIIAIKDILR--PTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRY 161
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK---TYDVEMK--LTSV 197
+ ++ G+ ++HS +++HRDLKP NLLV +K+ DFG+A+ T E + +T
Sbjct: 162 FLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEY 221
Query: 198 VVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L Y A+D+WS GC+ ++ RR L PG + QL I
Sbjct: 222 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLI 274
>AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated protein
kinase 7 transcript variant 5 protein.
Length = 533
Score = 130 bits (314), Expect = 5e-30
Identities = 78/233 (33%), Positives = 124/233 (53%), Gaps = 13/233 (5%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +YE + IG GAYG V AR G Q VA+KK+ A T+RE+ +L+
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQ-VAIKKIPNAFDVVTNAKRTLRELKILK 107
Query: 83 QLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRS 142
++H NI+ + D+ + + +++V + +E DL + + PL +R
Sbjct: 108 H---FKHDNIIAIKDILR--PTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRY 161
Query: 143 MSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAK---TYDVEMK--LTSV 197
+ ++ G+ ++HS +++HRDLKP NLLV +K+ DFG+A+ T E + +T
Sbjct: 162 FLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEY 221
Query: 198 VVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L Y A+D+WS GC+ ++ RR L PG + QL I
Sbjct: 222 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLI 274
>BC099905-1|AAH99905.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 129 bits (312), Expect = 8e-30
Identities = 81/233 (34%), Positives = 124/233 (53%), Gaps = 15/233 (6%)
Query: 22 LFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALL 81
+F +Y LS IG GAYG V A D N + VA+KK+ T+REI +L
Sbjct: 18 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR-VAIKKIS-PFEHQTYCQRTLREIKIL 75
Query: 82 RQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIR 141
+ RH NI+ + D+ +Q +++V + +E DL L L I
Sbjct: 76 LRS---RHENIIGINDIIRAPTI---EQMKDVYIVQDLMETDLYKLLKTQH--LSNDHIC 127
Query: 142 SMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMK----LTSV 197
+ I+ G+ ++HS ++HRDLKP NLL+ +++ DFGLA+ D + LT
Sbjct: 128 YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLEICDFGLARVADPDHDHTGFLTEY 187
Query: 198 VVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
V T WYR PE++L ++ Y ++D+WS GC+LA++ + RP+ PG DQL+ I
Sbjct: 188 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 240
>AF015256-1|AAC51758.1| 365|Homo sapiens p38 mitogen-activated
protein kinase protein.
Length = 365
Score = 129 bits (311), Expect = 1e-29
Identities = 77/218 (35%), Positives = 117/218 (53%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK-VAIKKPSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKVLDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFRGKDYLDQLTQILK 237
>U35003-1|AAC50609.1| 424|Homo sapiens JNK2 beta2 protein kinase
protein.
Length = 424
Score = 128 bits (310), Expect = 1e-29
Identities = 79/235 (33%), Positives = 124/235 (52%), Gaps = 9/235 (3%)
Query: 15 SINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLST 74
S+ + F ++Y++L IG+GA G V A D G VA+KK+
Sbjct: 12 SVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGIS-VAVKKLSRPFQNQTHAKRA 70
Query: 75 VREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP 134
RE+ LL+ H NI+ LL+V + LE Q + +LV E ++ +L +
Sbjct: 71 YRELVLLK---CVNHKNIISLLNVFTPQKTLEEFQDV--YLVMELMDANLCQVIHME--- 122
Query: 135 LPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL 194
L R+ + + ++ G+ LHS I+HRDLKP N++V +K+ DFGLA+T +
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMM 182
Query: 195 TSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T VVT +YR PEV+LG Y +D+WS GC++A++ + L PG DQ +++
Sbjct: 183 TPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKV 237
>U35002-1|AAC50608.1| 382|Homo sapiens JNK2 beta1 protein kinase
protein.
Length = 382
Score = 128 bits (310), Expect = 1e-29
Identities = 79/235 (33%), Positives = 124/235 (52%), Gaps = 9/235 (3%)
Query: 15 SINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLST 74
S+ + F ++Y++L IG+GA G V A D G VA+KK+
Sbjct: 12 SVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGIS-VAVKKLSRPFQNQTHAKRA 70
Query: 75 VREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP 134
RE+ LL+ H NI+ LL+V + LE Q + +LV E ++ +L +
Sbjct: 71 YRELVLLK---CVNHKNIISLLNVFTPQKTLEEFQDV--YLVMELMDANLCQVIHME--- 122
Query: 135 LPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL 194
L R+ + + ++ G+ LHS I+HRDLKP N++V +K+ DFGLA+T +
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMM 182
Query: 195 TSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T VVT +YR PEV+LG Y +D+WS GC++A++ + L PG DQ +++
Sbjct: 183 TPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKV 237
>X80692-1|CAA56709.1| 721|Homo sapiens p97mapk protein.
Length = 721
Score = 128 bits (309), Expect = 2e-29
Identities = 82/244 (33%), Positives = 133/244 (54%), Gaps = 20/244 (8%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +Y +L +G G G V+ A D ++ + VA+KK+ LT+ +REI ++R
Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVD-NDCDKRVAIKKI--VLTDPQSVKHALREIKIIR 70
Query: 83 QLEAYRHPNIVRLLDVC--HGGQCLERDQQLV----LFLVFEHVEQDLDSFLSRAPGPLP 136
+L+ H NIV++ ++ G Q + L +++V E++E DL + L + GPL
Sbjct: 71 RLD---HDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ--GPLL 125
Query: 137 ESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRV-KLADFGLAKTYDVEMK-- 193
E R + ++ G+ ++HS ++HRDLKP NL + V K+ DFGLA+ D
Sbjct: 126 EEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHK 185
Query: 194 --LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
L+ +VT WYR P +LL Y A+D+W+AGC+ A++ T + L GA + +Q+ I
Sbjct: 186 GHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLIL 245
Query: 251 RSGP 254
S P
Sbjct: 246 ESIP 249
>L77964-1|AAA98769.1| 721|Homo sapiens ERK3 protein kinase protein.
Length = 721
Score = 128 bits (309), Expect = 2e-29
Identities = 82/244 (33%), Positives = 133/244 (54%), Gaps = 20/244 (8%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +Y +L +G G G V+ A D ++ + VA+KK+ LT+ +REI ++R
Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVD-NDCDKRVAIKKI--VLTDPQSVKHALREIKIIR 70
Query: 83 QLEAYRHPNIVRLLDVC--HGGQCLERDQQLV----LFLVFEHVEQDLDSFLSRAPGPLP 136
+L+ H NIV++ ++ G Q + L +++V E++E DL + L + GPL
Sbjct: 71 RLD---HDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ--GPLL 125
Query: 137 ESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRV-KLADFGLAKTYDVEMK-- 193
E R + ++ G+ ++HS ++HRDLKP NL + V K+ DFGLA+ D
Sbjct: 126 EEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHK 185
Query: 194 --LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
L+ +VT WYR P +LL Y A+D+W+AGC+ A++ T + L GA + +Q+ I
Sbjct: 186 GHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLIL 245
Query: 251 RSGP 254
S P
Sbjct: 246 ESIP 249
>BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated protein
kinase 6 protein.
Length = 721
Score = 128 bits (309), Expect = 2e-29
Identities = 82/244 (33%), Positives = 133/244 (54%), Gaps = 20/244 (8%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +Y +L +G G G V+ A D ++ + VA+KK+ LT+ +REI ++R
Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVD-NDCDKRVAIKKI--VLTDPQSVKHALREIKIIR 70
Query: 83 QLEAYRHPNIVRLLDVC--HGGQCLERDQQLV----LFLVFEHVEQDLDSFLSRAPGPLP 136
+L+ H NIV++ ++ G Q + L +++V E++E DL + L + GPL
Sbjct: 71 RLD---HDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ--GPLL 125
Query: 137 ESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRV-KLADFGLAKTYDVEMK-- 193
E R + ++ G+ ++HS ++HRDLKP NL + V K+ DFGLA+ D
Sbjct: 126 EEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHK 185
Query: 194 --LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
L+ +VT WYR P +LL Y A+D+W+AGC+ A++ T + L GA + +Q+ I
Sbjct: 186 GHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLIL 245
Query: 251 RSGP 254
S P
Sbjct: 246 ESIP 249
>AF420474-1|AAL17605.1| 721|Homo sapiens ERK-3 protein.
Length = 721
Score = 128 bits (309), Expect = 2e-29
Identities = 82/244 (33%), Positives = 133/244 (54%), Gaps = 20/244 (8%)
Query: 23 FQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLR 82
F +Y +L +G G G V+ A D ++ + VA+KK+ LT+ +REI ++R
Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVD-NDCDKRVAIKKI--VLTDPQSVKHALREIKIIR 70
Query: 83 QLEAYRHPNIVRLLDVC--HGGQCLERDQQLV----LFLVFEHVEQDLDSFLSRAPGPLP 136
+L+ H NIV++ ++ G Q + L +++V E++E DL + L + GPL
Sbjct: 71 RLD---HDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ--GPLL 125
Query: 137 ESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRV-KLADFGLAKTYDVEMK-- 193
E R + ++ G+ ++HS ++HRDLKP NL + V K+ DFGLA+ D
Sbjct: 126 EEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHK 185
Query: 194 --LTSVVVTLWYRPPEVLLGA-RYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIF 250
L+ +VT WYR P +LL Y A+D+W+AGC+ A++ T + L GA + +Q+ I
Sbjct: 186 GHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLIL 245
Query: 251 RSGP 254
S P
Sbjct: 246 ESIP 249
>AF004709-1|AAC51374.1| 365|Homo sapiens stress-activated protein
kinase 4 protein.
Length = 365
Score = 128 bits (309), Expect = 2e-29
Identities = 76/218 (34%), Positives = 117/218 (53%), Gaps = 12/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+ A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 31 VGSGAYGSWCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 86
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 87 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQMLKGLKYI 141
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 142 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 199
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFR 251
Y +D+WS GC++A++ T + L G DQL +I +
Sbjct: 200 YNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILK 237
>BC024247-1|AAH24247.1| 502|Homo sapiens CDC2L6 protein protein.
Length = 502
Score = 128 bits (308), Expect = 2e-29
Identities = 76/185 (41%), Positives = 112/185 (60%), Gaps = 26/185 (14%)
Query: 69 GIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDL---- 124
GI +S REIALLR+L +HPN++ L V L + V +L+F++ E DL
Sbjct: 58 GISMSACREIALLREL---KHPNVIALQKVF-----LSHSDRKV-WLLFDYAEHDLWHII 108
Query: 125 ----DSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLV----TVAGR 176
S ++ P LP S ++S+ + I+ G+ +LH++ ++HRDLKP N+LV GR
Sbjct: 109 KFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGR 168
Query: 177 VKLADFGLAKTYDVEMK----LTSVVVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLH 231
VK+AD G A+ ++ +K L VVVT WYR PE+LLGAR Y A+D+W+ GC+ A+L
Sbjct: 169 VKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELL 228
Query: 232 TRRPL 236
T P+
Sbjct: 229 TSEPI 233
>Y14440-1|CAA74792.1| 364|Homo sapiens stress activated protein
kinase-2b protein.
Length = 364
Score = 126 bits (305), Expect = 6e-29
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 11/224 (4%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+ + L +G+GAYG+V A D Q VA+KK+ T RE+ LL+ L
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLR-QKVAVKKLSRPFQSLIHARRTYRELRLLKHL-- 78
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H N++ LLDV +E ++ +LV + DL++ + L + ++ + +
Sbjct: 79 -KHENVIGLLDVFTPATSIEDFSEV--YLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQ 133
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
++ G+ ++HS I+HRDLKP N+ V +++ DFGLA+ D EM T V T WYR P
Sbjct: 134 LLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM--TGYVATRWYRAP 191
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
E++L Y +D+WS GC++A+L + L PG+ DQL RI
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 235
>U92268-1|AAB66313.1| 364|Homo sapiens mitogen activated protein
kinase p38-2 protein.
Length = 364
Score = 126 bits (305), Expect = 6e-29
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 11/224 (4%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+ + L +G+GAYG+V A D Q VA+KK+ T RE+ LL+ L
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLR-QKVAVKKLSRPFQSLIHARRTYRELRLLKHL-- 78
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H N++ LLDV +E ++ +LV + DL++ + L + ++ + +
Sbjct: 79 -KHENVIGLLDVFTPATSIEDFSEV--YLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQ 133
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
++ G+ ++HS I+HRDLKP N+ V +++ DFGLA+ D EM T V T WYR P
Sbjct: 134 LLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM--TGYVATRWYRAP 191
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
E++L Y +D+WS GC++A+L + L PG+ DQL RI
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 235
>DQ279722-1|ABB72677.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 126 bits (305), Expect = 6e-29
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 11/224 (4%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+ + L +G+GAYG+V A D Q VA+KK+ T RE+ LL+ L
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLR-QKVAVKKLSRPFQSLIHARRTYRELRLLKHL-- 78
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H N++ LLDV +E ++ +LV + DL++ + L + ++ + +
Sbjct: 79 -KHENVIGLLDVFTPATSIEDFSEV--YLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQ 133
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
++ G+ ++HS I+HRDLKP N+ V +++ DFGLA+ D EM T V T WYR P
Sbjct: 134 LLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM--TGYVATRWYRAP 191
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
E++L Y +D+WS GC++A+L + L PG+ DQL RI
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 235
>CR456514-1|CAG30400.1| 364|Homo sapiens MAPK11 protein.
Length = 364
Score = 126 bits (305), Expect = 6e-29
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 11/224 (4%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+ + L +G+GAYG+V A D Q VA+KK+ T RE+ LL+ L
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLR-QKVAVKKLSRPFQSLIHARRTYRELRLLKHL-- 78
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H N++ LLDV +E ++ +LV + DL++ + L + ++ + +
Sbjct: 79 -KHENVIGLLDVFTPATSIEDFSEV--YLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQ 133
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
++ G+ ++HS I+HRDLKP N+ V +++ DFGLA+ D EM T V T WYR P
Sbjct: 134 LLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM--TGYVATRWYRAP 191
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
E++L Y +D+WS GC++A+L + L PG+ DQL RI
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 235
>BC027933-1|AAH27933.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 126 bits (305), Expect = 6e-29
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 11/224 (4%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+ + L +G+GAYG+V A D Q VA+KK+ T RE+ LL+ L
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLR-QKVAVKKLSRPFQSLIHARRTYRELRLLKHL-- 78
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H N++ LLDV +E ++ +LV + DL++ + L + ++ + +
Sbjct: 79 -KHENVIGLLDVFTPATSIEDFSEV--YLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQ 133
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
++ G+ ++HS I+HRDLKP N+ V +++ DFGLA+ D EM T V T WYR P
Sbjct: 134 LLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM--TGYVATRWYRAP 191
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
E++L Y +D+WS GC++A+L + L PG+ DQL RI
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 235
>AL022328-13|CAB51539.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 126 bits (305), Expect = 6e-29
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 11/224 (4%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+ + L +G+GAYG+V A D Q VA+KK+ T RE+ LL+ L
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLR-QKVAVKKLSRPFQSLIHARRTYRELRLLKHL-- 78
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H N++ LLDV +E ++ +LV + DL++ + L + ++ + +
Sbjct: 79 -KHENVIGLLDVFTPATSIEDFSEV--YLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQ 133
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
++ G+ ++HS I+HRDLKP N+ V +++ DFGLA+ D EM T V T WYR P
Sbjct: 134 LLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM--TGYVATRWYRAP 191
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
E++L Y +D+WS GC++A+L + L PG+ DQL RI
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 235
>AF031135-1|AAC12714.1| 364|Homo sapiens p38beta2 MAP kinase
protein.
Length = 364
Score = 126 bits (305), Expect = 6e-29
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 11/224 (4%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+ + L +G+GAYG+V A D Q VA+KK+ T RE+ LL+ L
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLR-QKVAVKKLSRPFQSLIHARRTYRELRLLKHL-- 78
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H N++ LLDV +E ++ +LV + DL++ + L + ++ + +
Sbjct: 79 -KHENVIGLLDVFTPATSIEDFSEV--YLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQ 133
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
++ G+ ++HS I+HRDLKP N+ V +++ DFGLA+ D EM T V T WYR P
Sbjct: 134 LLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM--TGYVATRWYRAP 191
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
E++L Y +D+WS GC++A+L + L PG+ DQL RI
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 235
>AF001174-1|AAC51373.1| 364|Homo sapiens p38beta2 MAP kinase
protein.
Length = 364
Score = 126 bits (305), Expect = 6e-29
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 11/224 (4%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+ + L +G+GAYG+V A D Q VA+KK+ T RE+ LL+ L
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLR-QKVAVKKLSRPFQSLIHARRTYRELRLLKHL-- 78
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H N++ LLDV +E ++ +LV + DL++ + L + ++ + +
Sbjct: 79 -KHENVIGLLDVFTPATSIEDFSEV--YLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQ 133
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
++ G+ ++HS I+HRDLKP N+ V +++ DFGLA+ D EM T V T WYR P
Sbjct: 134 LLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM--TGYVATRWYRAP 191
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
E++L Y +D+WS GC++A+L + L PG+ DQL RI
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 235
>AF001008-1|AAC51250.1| 364|Homo sapiens p38Beta2 MAP Kinase
protein.
Length = 364
Score = 126 bits (305), Expect = 6e-29
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 11/224 (4%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+ + L +G+GAYG+V A D Q VA+KK+ T RE+ LL+ L
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLR-QKVAVKKLSRPFQSLIHARRTYRELRLLKHL-- 78
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHD 146
+H N++ LLDV +E ++ +LV + DL++ + L + ++ + +
Sbjct: 79 -KHENVIGLLDVFTPATSIEDFSEV--YLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQ 133
Query: 147 IISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPP 206
++ G+ ++HS I+HRDLKP N+ V +++ DFGLA+ D EM T V T WYR P
Sbjct: 134 LLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM--TGYVATRWYRAP 191
Query: 207 EVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
E++L Y +D+WS GC++A+L + L PG+ DQL RI
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 235
>AK222922-1|BAD96642.1| 307|Homo sapiens MAPK13 protein (Fragment)
variant protein.
Length = 307
Score = 126 bits (304), Expect = 8e-29
Identities = 73/206 (35%), Positives = 112/206 (54%), Gaps = 12/206 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
+G+GAYG+V A D +G + VA+KK+ + RE+ LL+ ++ H N++
Sbjct: 28 VGSGAYGSVCSAIDKRSGEK-VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ---HENVIG 83
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LLDV L +LV ++ DL + E +I+ + + ++ G+ ++
Sbjct: 84 LLDVFTPASSLRNFYDF--YLVMPFMQTDLQKIMGME---FSEEKIQYLVYQVLKGLKYI 138
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLG-AR 213
HS +VHRDLKP NL V +K+ DFGLA+ D EM T VVT WYR PEV+L
Sbjct: 139 HSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM--TGYVVTRWYRAPEVILSWMH 196
Query: 214 YCSALDVWSAGCVLAQLHTRRPLLPG 239
Y +D+WS GC++A++ T + L G
Sbjct: 197 YNQTVDIWSVGCIMAEMLTGKTLFKG 222
>AC006023-1|AAD54514.1| 727|Homo sapiens WUGSC:H_DJ1147A01.1
protein.
Length = 727
Score = 126 bits (303), Expect = 1e-28
Identities = 60/141 (42%), Positives = 87/141 (61%), Gaps = 3/141 (2%)
Query: 114 FLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTV 173
+LVFE+++ DL L E+ I+S ++ G+D+ H +HRD+K N+L+
Sbjct: 3 YLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNN 62
Query: 174 AGRVKLADFGLAKTYDVE--MKLTSVVVTLWYRPPEVLLG-ARYCSALDVWSAGCVLAQL 230
G++KLADFGLA+ Y E T+ V+TLWYRPPE+LLG RY A+DVWS GC+L +L
Sbjct: 63 RGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGEL 122
Query: 231 HTRRPLLPGASDSDQLHRIFR 251
T++P+ + QL I R
Sbjct: 123 FTKKPIFQANQELAQLELISR 143
>AL603914-3|CAI41173.1| 251|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 251
Score = 124 bits (299), Expect = 3e-28
Identities = 74/182 (40%), Positives = 110/182 (60%), Gaps = 26/182 (14%)
Query: 72 LSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDL------- 124
+S REIALLR+L +HPN++ L V L + V +L+F++ E DL
Sbjct: 1 MSACREIALLREL---KHPNVIALQKVF-----LSHSDRKV-WLLFDYAEHDLWHIIKFH 51
Query: 125 -DSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKL 179
S ++ P LP S ++S+ + I+ G+ +LH++ ++HRDLKP N+LV GRVK+
Sbjct: 52 RASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKI 111
Query: 180 ADFGLAKTYDVEMK----LTSVVVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRR 234
AD G A+ ++ +K L VVVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T
Sbjct: 112 ADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSE 171
Query: 235 PL 236
P+
Sbjct: 172 PI 173
>AL603914-2|CAI41172.1| 442|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 442
Score = 124 bits (299), Expect = 3e-28
Identities = 74/182 (40%), Positives = 110/182 (60%), Gaps = 26/182 (14%)
Query: 72 LSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDL------- 124
+S REIALLR+L +HPN++ L V L + V +L+F++ E DL
Sbjct: 1 MSACREIALLREL---KHPNVIALQKVF-----LSHSDRKV-WLLFDYAEHDLWHIIKFH 51
Query: 125 -DSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKL 179
S ++ P LP S ++S+ + I+ G+ +LH++ ++HRDLKP N+LV GRVK+
Sbjct: 52 RASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKI 111
Query: 180 ADFGLAKTYDVEMK----LTSVVVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRR 234
AD G A+ ++ +K L VVVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T
Sbjct: 112 ADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSE 171
Query: 235 PL 236
P+
Sbjct: 172 PI 173
>AL512430-2|CAI40283.1| 251|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 251
Score = 124 bits (299), Expect = 3e-28
Identities = 74/182 (40%), Positives = 110/182 (60%), Gaps = 26/182 (14%)
Query: 72 LSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDL------- 124
+S REIALLR+L +HPN++ L V L + V +L+F++ E DL
Sbjct: 1 MSACREIALLREL---KHPNVIALQKVF-----LSHSDRKV-WLLFDYAEHDLWHIIKFH 51
Query: 125 -DSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKL 179
S ++ P LP S ++S+ + I+ G+ +LH++ ++HRDLKP N+LV GRVK+
Sbjct: 52 RASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKI 111
Query: 180 ADFGLAKTYDVEMK----LTSVVVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRR 234
AD G A+ ++ +K L VVVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T
Sbjct: 112 ADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSE 171
Query: 235 PL 236
P+
Sbjct: 172 PI 173
>AL512430-1|CAI40282.1| 442|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 442
Score = 124 bits (299), Expect = 3e-28
Identities = 74/182 (40%), Positives = 110/182 (60%), Gaps = 26/182 (14%)
Query: 72 LSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDL------- 124
+S REIALLR+L +HPN++ L V L + V +L+F++ E DL
Sbjct: 1 MSACREIALLREL---KHPNVIALQKVF-----LSHSDRKV-WLLFDYAEHDLWHIIKFH 51
Query: 125 -DSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLV----TVAGRVKL 179
S ++ P LP S ++S+ + I+ G+ +LH++ ++HRDLKP N+LV GRVK+
Sbjct: 52 RASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKI 111
Query: 180 ADFGLAKTYDVEMK----LTSVVVTLWYRPPEVLLGAR-YCSALDVWSAGCVLAQLHTRR 234
AD G A+ ++ +K L VVVT WYR PE+LLGAR Y A+D+W+ GC+ A+L T
Sbjct: 112 ADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSE 171
Query: 235 PL 236
P+
Sbjct: 172 PI 173
>DQ316259-1|ABC40748.1| 516|Homo sapiens nemo like kinase protein.
Length = 516
Score = 124 bits (298), Expect = 4e-28
Identities = 78/218 (35%), Positives = 119/218 (54%), Gaps = 11/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
IG GA+G V+ D +G + VA+KK+ +S R L+ L ++H N++
Sbjct: 133 IGYGAFGVVWSVTDPRDGKR-VALKKMPNVFQN---LVSCKRVFRELKMLCFFKHDNVLS 188
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LD+ Q D +++V E ++ DL + +P PL ++ + I+ G+ +L
Sbjct: 189 ALDIL---QPPHIDYFEEIYVVTELMQSDLHKIIV-SPQPLSSDHVKVFLYQILRGLKYL 244
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKT--YDVEMKLTSVVVTLWYRPPEVLLGA 212
HS I+HRD+KP NLLV +K+ DFGLA+ D +T VVT +YR PE+L+G+
Sbjct: 245 HSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGS 304
Query: 213 R-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
R Y +A+D+WS GC+ A+L RR L S QL I
Sbjct: 305 RHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLI 342
>BC064663-1|AAH64663.1| 515|Homo sapiens nemo-like kinase protein.
Length = 515
Score = 124 bits (298), Expect = 4e-28
Identities = 78/218 (35%), Positives = 119/218 (54%), Gaps = 11/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
IG GA+G V+ D +G + VA+KK+ +S R L+ L ++H N++
Sbjct: 132 IGYGAFGVVWSVTDPRDGKR-VALKKMPNVFQN---LVSCKRVFRELKMLCFFKHDNVLS 187
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LD+ Q D +++V E ++ DL + +P PL ++ + I+ G+ +L
Sbjct: 188 ALDIL---QPPHIDYFEEIYVVTELMQSDLHKIIV-SPQPLSSDHVKVFLYQILRGLKYL 243
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKT--YDVEMKLTSVVVTLWYRPPEVLLGA 212
HS I+HRD+KP NLLV +K+ DFGLA+ D +T VVT +YR PE+L+G+
Sbjct: 244 HSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGS 303
Query: 213 R-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
R Y +A+D+WS GC+ A+L RR L S QL I
Sbjct: 304 RHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLI 341
>AF197898-1|AAF04857.1| 515|Homo sapiens nemo-like kinase protein.
Length = 515
Score = 124 bits (298), Expect = 4e-28
Identities = 78/218 (35%), Positives = 119/218 (54%), Gaps = 11/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
IG GA+G V+ D +G + VA+KK+ +S R L+ L ++H N++
Sbjct: 132 IGYGAFGVVWSVTDPRDGKR-VALKKMPNVFQN---LVSCKRVFRELKMLCFFKHDNVLS 187
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LD+ Q D +++V E ++ DL + +P PL ++ + I+ G+ +L
Sbjct: 188 ALDIL---QPPHIDYFEEIYVVTELMQSDLHKIIV-SPQPLSSDHVKVFLYQILRGLKYL 243
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKT--YDVEMKLTSVVVTLWYRPPEVLLGA 212
HS I+HRD+KP NLLV +K+ DFGLA+ D +T VVT +YR PE+L+G+
Sbjct: 244 HSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGS 303
Query: 213 R-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
R Y +A+D+WS GC+ A+L RR L S QL I
Sbjct: 304 RHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLI 341
>AF180819-1|AAD56013.1| 515|Homo sapiens LAK1 protein protein.
Length = 515
Score = 124 bits (298), Expect = 4e-28
Identities = 78/218 (35%), Positives = 119/218 (54%), Gaps = 11/218 (5%)
Query: 35 IGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVR 94
IG GA+G V+ D +G + VA+KK+ +S R L+ L ++H N++
Sbjct: 132 IGYGAFGVVWSVTDPRDGKR-VALKKMPNVFQN---LVSCKRVFRELKMLCFFKHDNVLS 187
Query: 95 LLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFL 154
LD+ Q D +++V E ++ DL + +P PL ++ + I+ G+ +L
Sbjct: 188 ALDIL---QPPHIDYFEEIYVVTELMQSDLHKIIV-SPQPLSSDHVKVFLYQILRGLKYL 243
Query: 155 HSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKT--YDVEMKLTSVVVTLWYRPPEVLLGA 212
HS I+HRD+KP NLLV +K+ DFGLA+ D +T VVT +YR PE+L+G+
Sbjct: 244 HSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGS 303
Query: 213 R-YCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
R Y +A+D+WS GC+ A+L RR L S QL I
Sbjct: 304 RHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLI 341
>U53442-1|AAB05036.1| 372|Homo sapiens p38Beta MAP kinase protein.
Length = 372
Score = 123 bits (297), Expect = 5e-28
Identities = 80/230 (34%), Positives = 122/230 (53%), Gaps = 15/230 (6%)
Query: 27 QKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEA 86
Q+ + L +G+GAYG+V A D Q VA+KK+ T RE+ LL+ L
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLR-QKVAVKKLSRPFQSLIHARRTYRELRLLKHL-- 78
Query: 87 YRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSH- 145
+H N++ LLDV +E ++ +LV + DL++ + G +R+ H
Sbjct: 79 -KHENVIGLLDVFTPATSIEDFSEV--YLVTTLMGADLNNIVKCQAGAHQGARLALDEHV 135
Query: 146 -----DIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVT 200
++ G+ ++HS I+HRDLKP N+ V +++ DFGLA+ D EM T V T
Sbjct: 136 QFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM--TGYVAT 193
Query: 201 LWYRPPEVLLG-ARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
WYR PE++L Y +D+WS GC++A+L + L PG+ DQL RI
Sbjct: 194 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRI 243
>U34820-1|AAC50605.1| 422|Homo sapiens JNK3 alpha1 protein kinase
protein.
Length = 422
Score = 123 bits (297), Expect = 5e-28
Identities = 76/235 (32%), Positives = 121/235 (51%), Gaps = 9/235 (3%)
Query: 15 SINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLST 74
S+ + F ++Y+ L IG+GA G V A D VA+KK+
Sbjct: 50 SVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRN-VAIKKLSRPFQNQTHAKRA 108
Query: 75 VREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP 134
RE+ L++ H NI+ LL+V + LE Q + +LV E ++ +L +
Sbjct: 109 YRELVLMK---CVNHKNIISLLNVFTPQKTLEEFQDV--YLVMELMDANLCQVIQME--- 160
Query: 135 LPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL 194
L R+ + + ++ G+ LHS I+HRDLKP N++V +K+ DFGLA+T +
Sbjct: 161 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMM 220
Query: 195 TSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T VVT +YR PEV+LG Y +D+WS GC++ ++ + L PG DQ +++
Sbjct: 221 TPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKV 275
>U34819-1|AAC50604.1| 464|Homo sapiens JNK3 alpha2 protein kinase
protein.
Length = 464
Score = 123 bits (297), Expect = 5e-28
Identities = 76/235 (32%), Positives = 121/235 (51%), Gaps = 9/235 (3%)
Query: 15 SINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLST 74
S+ + F ++Y+ L IG+GA G V A D VA+KK+
Sbjct: 50 SVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRN-VAIKKLSRPFQNQTHAKRA 108
Query: 75 VREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP 134
RE+ L++ H NI+ LL+V + LE Q + +LV E ++ +L +
Sbjct: 109 YRELVLMK---CVNHKNIISLLNVFTPQKTLEEFQDV--YLVMELMDANLCQVIQME--- 160
Query: 135 LPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL 194
L R+ + + ++ G+ LHS I+HRDLKP N++V +K+ DFGLA+T +
Sbjct: 161 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMM 220
Query: 195 TSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T VVT +YR PEV+LG Y +D+WS GC++ ++ + L PG DQ +++
Sbjct: 221 TPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKV 275
>U07620-1|AAC50101.1| 422|Homo sapiens MAP kinase protein.
Length = 422
Score = 123 bits (297), Expect = 5e-28
Identities = 76/235 (32%), Positives = 121/235 (51%), Gaps = 9/235 (3%)
Query: 15 SINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLST 74
S+ + F ++Y+ L IG+GA G V A D VA+KK+
Sbjct: 50 SVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRN-VAIKKLSRPFQNQTHAKRA 108
Query: 75 VREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP 134
RE+ L++ H NI+ LL+V + LE Q + +LV E ++ +L +
Sbjct: 109 YRELVLMK---CVNHKNIISLLNVFTPQKTLEEFQDV--YLVMELMDANLCQVIQME--- 160
Query: 135 LPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL 194
L R+ + + ++ G+ LHS I+HRDLKP N++V +K+ DFGLA+T +
Sbjct: 161 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMM 220
Query: 195 TSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T VVT +YR PEV+LG Y +D+WS GC++ ++ + L PG DQ +++
Sbjct: 221 TPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKV 275
>BC035057-1|AAH35057.1| 464|Homo sapiens MAPK10 protein protein.
Length = 464
Score = 123 bits (297), Expect = 5e-28
Identities = 76/235 (32%), Positives = 121/235 (51%), Gaps = 9/235 (3%)
Query: 15 SINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLST 74
S+ + F ++Y+ L IG+GA G V A D VA+KK+
Sbjct: 50 SVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRN-VAIKKLSRPFQNQTHAKRA 108
Query: 75 VREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGP 134
RE+ L++ H NI+ LL+V + LE Q + +LV E ++ +L +
Sbjct: 109 YRELVLMK---CVNHKNIISLLNVFTPQKTLEEFQDV--YLVMELMDANLCQVIQME--- 160
Query: 135 LPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKL 194
L R+ + + ++ G+ LHS I+HRDLKP N++V +K+ DFGLA+T +
Sbjct: 161 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMM 220
Query: 195 TSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRI 249
T VVT +YR PEV+LG Y +D+WS GC++ ++ + L PG DQ +++
Sbjct: 221 TPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKV 275
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.137 0.406
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 38,364,191
Number of Sequences: 224733
Number of extensions: 1543523
Number of successful extensions: 9452
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2579
Number of HSP's successfully gapped in prelim test: 199
Number of HSP's that attempted gapping in prelim test: 2855
Number of HSP's gapped (non-prelim): 3314
length of query: 255
length of database: 73,234,838
effective HSP length: 88
effective length of query: 167
effective length of database: 53,458,334
effective search space: 8927541778
effective search space used: 8927541778
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 64 (29.9 bits)
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