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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001335-TA|BGIBMGA001335-PA|IPR001269|Dihydrouridine
synthase, DuS
         (591 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q17M24 Cluster: tRNA-dihydrouridine synthase; n=1; Aede...   643   0.0  
UniRef50_Q7PVV7 Cluster: ENSANGP00000016833; n=2; Endopterygota|...   641   0.0  
UniRef50_A7S213 Cluster: Predicted protein; n=1; Nematostella ve...   620   e-176
UniRef50_Q9VIS4 Cluster: CG10463-PA; n=3; Sophophora|Rep: CG1046...   606   e-172
UniRef50_Q96G46 Cluster: tRNA-dihydrouridine synthase 3-like; n=...   586   e-166
UniRef50_Q91XI1 Cluster: tRNA-dihydrouridine synthase 3-like; n=...   583   e-165
UniRef50_UPI000058804E Cluster: PREDICTED: similar to MGC53781 p...   549   e-155
UniRef50_Q6PEH0 Cluster: Zgc:63779; n=8; Chordata|Rep: Zgc:63779...   541   e-152
UniRef50_A4RQU5 Cluster: Predicted protein; n=2; Ostreococcus|Re...   489   e-137
UniRef50_UPI00015B6197 Cluster: PREDICTED: similar to CG10463-PA...   483   e-135
UniRef50_Q9TYN2 Cluster: Putative uncharacterized protein Y37E11...   455   e-126
UniRef50_Q01ML2 Cluster: H0613H07.1 protein; n=10; Eukaryota|Rep...   451   e-125
UniRef50_Q582L4 Cluster: TRNA-dihydrouridine synthase 3, putativ...   418   e-115
UniRef50_Q54CU9 Cluster: Putative uncharacterized protein; n=1; ...   415   e-114
UniRef50_Q010A0 Cluster: tRNA-dihydrouridine synthase; n=1; Ostr...   410   e-113
UniRef50_Q5KC68 Cluster: TRNA dihydrouridine synthase, putative;...   407   e-112
UniRef50_Q4QEF9 Cluster: Putative uncharacterized protein; n=3; ...   404   e-111
UniRef50_A3LUK5 Cluster: Dihydrouridine synthase of tRNA; n=6; S...   399   e-109
UniRef50_Q6C4K3 Cluster: Similar to DEHA0D12364g Debaryomyces ha...   392   e-107
UniRef50_A4S3Q5 Cluster: Predicted protein; n=2; Eukaryota|Rep: ...   386   e-105
UniRef50_Q5CRK5 Cluster: Ylr401cp-like protein with 2 CCCH domai...   342   2e-92
UniRef50_UPI0000499494 Cluster: conserved hypothetical protein; ...   332   2e-89
UniRef50_Q9UTH9 Cluster: tRNA dihydrouridine synthase Dus3; n=1;...   324   4e-87
UniRef50_Q2UL89 Cluster: Uncharacterized conserved protein; n=15...   308   4e-82
UniRef50_Q06053 Cluster: tRNA-dihydrouridine synthase 3; n=6; Sa...   245   2e-63
UniRef50_Q2HDP2 Cluster: Putative uncharacterized protein; n=1; ...   244   7e-63
UniRef50_Q7X346 Cluster: Putative uncharacterized protein; n=1; ...   200   8e-50
UniRef50_A4S604 Cluster: Predicted protein; n=1; Ostreococcus lu...   197   8e-49
UniRef50_Q7R3K2 Cluster: GLP_158_4738_3071; n=1; Giardia lamblia...   183   1e-44
UniRef50_A4XH30 Cluster: Putative TIM-barrel protein, nifR3 fami...   157   8e-37
UniRef50_Q899H0 Cluster: Nitrogen regulation protein nifR3; n=24...   144   8e-33
UniRef50_A5BP75 Cluster: Putative uncharacterized protein; n=1; ...   140   1e-31
UniRef50_A6LGT0 Cluster: Putative TIM-barrel enzyme; n=1; Paraba...   138   5e-31
UniRef50_Q7MXX6 Cluster: TIM-barrel protein, putative, NifR3 fam...   136   1e-30
UniRef50_Q1IVR5 Cluster: Dihydrouridine synthase TIM-barrel prot...   135   3e-30
UniRef50_Q0F181 Cluster: Dihydrouridine synthase TIM-barrel prot...   135   3e-30
UniRef50_Q64MI4 Cluster: Putative TIM-barrel enzyme; n=3; Bacter...   133   1e-29
UniRef50_Q9RDC6 Cluster: Putative uncharacterized protein SCO249...   132   3e-29
UniRef50_Q8GQD1 Cluster: NifR; n=5; Leptospira|Rep: NifR - Lepto...   132   3e-29
UniRef50_Q6F288 Cluster: TRNA dihydrouridine synthetase; n=3; Mo...   132   3e-29
UniRef50_A1IF01 Cluster: Dihydrouridine synthase family protein;...   130   1e-28
UniRef50_Q6AJZ5 Cluster: TRNA-dihydrouridine synthase; n=1; Desu...   129   2e-28
UniRef50_Q1Q3Q8 Cluster: Strongly similar to tRNA-dihydrouridine...   129   2e-28
UniRef50_Q8KB61 Cluster: TIM-barrel protein, nifR3 family; n=10;...   128   3e-28
UniRef50_Q6MRF1 Cluster: Transcription regulator homolog yacF; n...   128   3e-28
UniRef50_Q0YFW9 Cluster: Dihydrouridine synthase TIM-barrel prot...   128   3e-28
UniRef50_Q1NXZ7 Cluster: Dihydrouridine synthase TIM-barrel prot...   128   4e-28
UniRef50_Q2RZL4 Cluster: NifR3 family enzyme; n=1; Salinibacter ...   128   5e-28
UniRef50_Q2IG49 Cluster: Dihydrouridine synthase TIM-barrel prot...   128   5e-28
UniRef50_A6CBK4 Cluster: Predicted TIM-barrel enzyme, possibly d...   127   9e-28
UniRef50_Q9Z7D8 Cluster: Predicted oxidoreductase; n=7; Chlamydi...   126   2e-27
UniRef50_Q5M689 Cluster: Possible transcriptional regulator; n=2...   126   2e-27
UniRef50_Q74EF7 Cluster: Dihydrouridine synthase family protein;...   125   3e-27
UniRef50_A2FJB5 Cluster: TIM-barrel protein, nifR3 family protei...   125   3e-27
UniRef50_A5D5Q0 Cluster: TRNA-dihydrouridine synthase; n=5; Firm...   125   4e-27
UniRef50_O25427 Cluster: Probable tRNA-dihydrouridine synthase; ...   124   9e-27
UniRef50_Q1VN28 Cluster: Dihydrouridine synthase TIM-barrel prot...   123   2e-26
UniRef50_Q9ZED2 Cluster: Probable tRNA-dihydrouridine synthase; ...   123   2e-26
UniRef50_A6EDJ3 Cluster: Probable TIM-barrel protein, NifR3 fami...   122   3e-26
UniRef50_P37567 Cluster: Probable tRNA-dihydrouridine synthase 1...   122   4e-26
UniRef50_A4TZK1 Cluster: Dihydrouridine synthase, DuS; n=4; Prot...   121   6e-26
UniRef50_A4EC62 Cluster: Putative uncharacterized protein; n=1; ...   120   1e-25
UniRef50_O67533 Cluster: Probable tRNA-dihydrouridine synthase; ...   120   1e-25
UniRef50_Q8G7W8 Cluster: Possible NifR3-like protein; n=4; Bifid...   119   2e-25
UniRef50_A5EVV4 Cluster: Dihydrouridine synthase; n=1; Dicheloba...   117   8e-25
UniRef50_Q6A959 Cluster: TIM-barrel enzyme, NifR3 family; n=1; P...   116   2e-24
UniRef50_A4M5I1 Cluster: Dihydrouridine synthase, DuS; n=1; Petr...   115   3e-24
UniRef50_A6PPM6 Cluster: Dihydrouridine synthase, DuS; n=1; Vict...   115   4e-24
UniRef50_Q9CLW3 Cluster: tRNA-dihydrouridine synthase B; n=17; P...   115   4e-24
UniRef50_A0LJ96 Cluster: Putative TIM-barrel protein, nifR3 fami...   113   9e-24
UniRef50_Q2RM54 Cluster: Dihydrouridine synthase TIM-barrel prot...   113   1e-23
UniRef50_A6NW05 Cluster: Putative uncharacterized protein; n=1; ...   113   1e-23
UniRef50_Q3E0H8 Cluster: Dihydrouridine synthase TIM-barrel prot...   113   2e-23
UniRef50_Q0B0N8 Cluster: Putative TIM-barrel protein, NifR3 fami...   113   2e-23
UniRef50_Q489F6 Cluster: NifR3/Smm1 family protein; n=2; Proteob...   112   2e-23
UniRef50_A6BZR9 Cluster: Predicted TIM-barrel enzyme, possibly d...   112   2e-23
UniRef50_A6DCX2 Cluster: tRNA-dihydrouridine synthase B; n=1; Ca...   112   3e-23
UniRef50_Q8PX79 Cluster: NifR3-like protein; n=5; Archaea|Rep: N...   111   4e-23
UniRef50_Q6M9N8 Cluster: Putative uncharacterized protein; n=1; ...   111   5e-23
UniRef50_Q6SFW7 Cluster: NifR3/Smm1 family protein; n=1; uncultu...   111   5e-23
UniRef50_Q6MAU6 Cluster: Putative uncharacterized protein yohI; ...   109   3e-22
UniRef50_Q251N6 Cluster: Putative uncharacterized protein; n=2; ...   107   6e-22
UniRef50_Q31II6 Cluster: Dihydrouridine synthase; n=1; Thiomicro...   107   8e-22
UniRef50_A4YUQ6 Cluster: Putative tRNA-dihydrouridine synthase; ...   107   8e-22
UniRef50_Q0G7A4 Cluster: Nitrogen regulation protein nifr3; n=2;...   107   1e-21
UniRef50_A7HK00 Cluster: Dihydrouridine synthase DuS; n=4; Therm...   107   1e-21
UniRef50_O53835 Cluster: Probable tRNA-dihydrouridine synthase; ...   107   1e-21
UniRef50_Q0FAI7 Cluster: tRNA-dihydrouridine synthase, putative;...   106   1e-21
UniRef50_Q8YAB9 Cluster: Lmo0227 protein; n=55; Bacteria|Rep: Lm...   106   2e-21
UniRef50_Q14SX5 Cluster: Putative dihydrouridine synthase; n=1; ...   106   2e-21
UniRef50_Q9RRP8 Cluster: NifR3 protein; n=2; Deinococcus|Rep: Ni...   105   3e-21
UniRef50_Q3AZ67 Cluster: Dihydrouridine synthase TIM-barrel prot...   105   3e-21
UniRef50_Q5FTP7 Cluster: Nitrogen assimilation regulatory protei...   104   6e-21
UniRef50_Q2RTR9 Cluster: Dihydrouridine synthase TIM-barrel prot...   104   6e-21
UniRef50_Q55724 Cluster: Probable tRNA-dihydrouridine synthase 1...   104   6e-21
UniRef50_O83945 Cluster: Probable tRNA-dihydrouridine synthase; ...   104   8e-21
UniRef50_Q00XL7 Cluster: TRNA-dihydrouridine synthase; n=1; Ostr...   103   1e-20
UniRef50_Q090Q9 Cluster: TRNA-dihydrouridine synthase B; n=2; Cy...   102   2e-20
UniRef50_A7BE39 Cluster: Putative uncharacterized protein; n=1; ...   102   2e-20
UniRef50_Q607L4 Cluster: TIM-barrel protein, yjbN family; n=10; ...   102   3e-20
UniRef50_A7CWF1 Cluster: Putative TIM-barrel protein, nifR3 fami...   101   7e-20
UniRef50_Q5ZRM0 Cluster: Nitrogen regulation protein; n=4; Legio...   100   1e-19
UniRef50_A6DPY9 Cluster: Putative uncharacterized protein; n=1; ...    99   2e-19
UniRef50_Q8RFK3 Cluster: Nitrogen regulation protein NIFR3; n=3;...    99   3e-19
UniRef50_Q0C0N1 Cluster: Putative tRNA-dihydrouridine synthase; ...    99   3e-19
UniRef50_Q5CSA9 Cluster: Dus1p, tRNA dihydrouridine synthase; n=...    99   4e-19
UniRef50_Q08111 Cluster: Probable tRNA-dihydrouridine synthase; ...    98   5e-19
UniRef50_Q89LQ7 Cluster: Nitrogen regulation protein; n=22; Alph...    98   7e-19
UniRef50_Q9A7I4 Cluster: Nitrogen regulation protein Nifr3; n=2;...    97   9e-19
UniRef50_A7DPL5 Cluster: Putative TIM-barrel protein, nifR3 fami...    97   9e-19
UniRef50_A0EG06 Cluster: Chromosome undetermined scaffold_94, wh...    96   3e-18
UniRef50_Q8ZAX7 Cluster: tRNA-dihydrouridine synthase B; n=214; ...    95   6e-18
UniRef50_Q54ES7 Cluster: Putative uncharacterized protein; n=1; ...    92   3e-17
UniRef50_Q1QZQ6 Cluster: Dihydrouridine synthase, DuS; n=1; Chro...    92   4e-17
UniRef50_Q8SUV4 Cluster: Putative uncharacterized protein ECU07_...    92   4e-17
UniRef50_A4RVX6 Cluster: Predicted protein; n=2; Ostreococcus|Re...    91   8e-17
UniRef50_A3VNG3 Cluster: Dihydrouridine synthase TIM-barrel prot...    91   1e-16
UniRef50_A4S141 Cluster: Predicted protein; n=1; Ostreococcus lu...    91   1e-16
UniRef50_A5K1E0 Cluster: tRNA-dihydrouridine synthase, putative;...    89   2e-16
UniRef50_Q9JUP6 Cluster: tRNA-dihydrouridine synthase C; n=4; Ne...    89   3e-16
UniRef50_O52532 Cluster: tRNA-dihydrouridine synthase B; n=6; Ga...    89   3e-16
UniRef50_O74553 Cluster: tRNA dihydrouridine synthase Dus4; n=1;...    89   4e-16
UniRef50_Q6P1R4 Cluster: tRNA-dihydrouridine synthase 1-like; n=...    88   7e-16
UniRef50_Q7UXK8 Cluster: Putative uncharacterized protein; n=3; ...    87   2e-15
UniRef50_Q7UKE8 Cluster: Putative uncharacterized protein; n=2; ...    87   2e-15
UniRef50_Q30WR3 Cluster: Dihydrouridine synthase family protein;...    87   2e-15
UniRef50_Q9FH91 Cluster: Gb|AAF51525.1; n=6; Magnoliophyta|Rep: ...    87   2e-15
UniRef50_Q9VPM1 Cluster: CG3645-PA, isoform A; n=2; Diptera|Rep:...    86   2e-15
UniRef50_Q9HGN6 Cluster: tRNA dihydrouridine synthase Dus1; n=1;...    86   2e-15
UniRef50_A6DU09 Cluster: Dihydrouridine synthase family protein;...    86   3e-15
UniRef50_Q00RI1 Cluster: OSIGBa0125M19.5 protein; n=9; Magnoliop...    85   7e-15
UniRef50_Q5LRN6 Cluster: TRNA-dihydrouridine synthase, putative;...    84   9e-15
UniRef50_Q54XQ6 Cluster: Putative uncharacterized protein; n=1; ...    84   9e-15
UniRef50_Q8YMN5 Cluster: Transcriptional regulator; n=5; Bacteri...    84   1e-14
UniRef50_A3RPJ2 Cluster: TRNA-dihydrouridine synthase; n=2; Prot...    83   2e-14
UniRef50_Q4PG83 Cluster: Putative uncharacterized protein; n=1; ...    83   2e-14
UniRef50_Q4AHG7 Cluster: Dihydrouridine synthase, DuS; n=1; Chlo...    82   4e-14
UniRef50_UPI0000D5693C Cluster: PREDICTED: similar to dihydrouri...    82   5e-14
UniRef50_Q47C15 Cluster: Dihydrouridine synthase, DuS; n=2; Beta...    82   5e-14
UniRef50_Q5A4Y0 Cluster: Potential tRNA dihydrouridine synthase;...    81   6e-14
UniRef50_A6W1E8 Cluster: Dihydrouridine synthase DuS; n=1; Marin...    81   8e-14
UniRef50_A1VHK2 Cluster: Dihydrouridine synthase, DuS; n=4; Desu...    81   8e-14
UniRef50_Q5KP54 Cluster: TRNA dihydrouridine synthase, putative;...    81   1e-13
UniRef50_Q8XYX1 Cluster: tRNA-dihydrouridine synthase C; n=26; P...    81   1e-13
UniRef50_A1SX05 Cluster: Dihydrouridine synthase, DuS; n=3; Alte...    80   1e-13
UniRef50_O95620 Cluster: tRNA-dihydrouridine synthase 4-like; n=...    80   1e-13
UniRef50_Q9VY45 Cluster: CG1434-PA; n=6; Endopterygota|Rep: CG14...    80   2e-13
UniRef50_Q8A2H9 Cluster: Putative nifR3 family TIM-barrel enzyme...    79   2e-13
UniRef50_A7AQM0 Cluster: Dihydrouridine synthase, putative; n=1;...    79   2e-13
UniRef50_A3JG66 Cluster: Putative uncharacterized protein; n=3; ...    79   4e-13
UniRef50_Q9XVN8 Cluster: Putative uncharacterized protein; n=2; ...    79   4e-13
UniRef50_P53759 Cluster: tRNA-dihydrouridine synthase 1; n=11; S...    79   4e-13
UniRef50_A6GHV6 Cluster: Dihydrouridine synthase family protein;...    78   6e-13
UniRef50_Q884C6 Cluster: tRNA-dihydrouridine synthase C; n=8; Pr...    78   6e-13
UniRef50_Q7RX85 Cluster: Putative uncharacterized protein NCU000...    77   1e-12
UniRef50_Q06063 Cluster: tRNA-dihydrouridine synthase 4; n=10; S...    77   1e-12
UniRef50_Q6MNE9 Cluster: Nitrogen regulation protein nifR3; n=1;...    77   1e-12
UniRef50_A4E892 Cluster: Putative uncharacterized protein; n=1; ...    76   2e-12
UniRef50_Q6AKJ6 Cluster: Putative uncharacterized protein; n=1; ...    76   3e-12
UniRef50_Q9XWJ9 Cluster: Putative uncharacterized protein; n=2; ...    76   3e-12
UniRef50_Q1JWD3 Cluster: Dihydrouridine synthase, DuS; n=1; Desu...    75   4e-12
UniRef50_A6PMB8 Cluster: Dihydrouridine synthase, DuS; n=1; Vict...    75   4e-12
UniRef50_Q127F8 Cluster: Dihydrouridine synthase, DuS; n=3; Prot...    75   5e-12
UniRef50_UPI00015B403F Cluster: PREDICTED: similar to MGC79829 p...    75   7e-12
UniRef50_A7T8A1 Cluster: Predicted protein; n=1; Nematostella ve...    75   7e-12
UniRef50_Q5HJT5 Cluster: Probable tRNA-dihydrouridine synthase; ...    75   7e-12
UniRef50_Q9VJ06 Cluster: CG10495-PA; n=2; Sophophora|Rep: CG1049...    74   1e-11
UniRef50_Q6AJ40 Cluster: Putative uncharacterized protein; n=1; ...    73   2e-11
UniRef50_Q9NX74 Cluster: tRNA-dihydrouridine synthase 2-like; n=...    73   2e-11
UniRef50_A7AAN4 Cluster: Putative uncharacterized protein; n=2; ...    72   4e-11
UniRef50_Q73RG6 Cluster: Dihydrouridine synthase, putative; n=1;...    72   5e-11
UniRef50_Q4D174 Cluster: Dihydrouridine synthase (Dus), putative...    72   5e-11
UniRef50_A6VYA3 Cluster: TIM-barrel protein, yjbN family; n=8; P...    71   9e-11
UniRef50_Q5KPM6 Cluster: Putative uncharacterized protein; n=2; ...    71   9e-11
UniRef50_Q4WRF0 Cluster: Dihydrouridine synthase family protein,...    71   1e-10
UniRef50_UPI0000499E32 Cluster: conserved hypothetical protein; ...    70   2e-10
UniRef50_Q1N033 Cluster: Putative uncharacterized protein; n=1; ...    70   2e-10
UniRef50_Q0IFC6 Cluster: tRNA-dihydrouridine synthase; n=2; Culi...    70   2e-10
UniRef50_A6P2M8 Cluster: Putative uncharacterized protein; n=1; ...    70   2e-10
UniRef50_A4AAB0 Cluster: TRNA-dihydrouridine synthase C; n=2; un...    69   3e-10
UniRef50_O74731 Cluster: tRNA dihydrouridine synthase Dus2; n=1;...    69   4e-10
UniRef50_Q54QJ2 Cluster: Putative uncharacterized protein; n=1; ...    69   5e-10
UniRef50_Q4S086 Cluster: Chromosome undetermined SCAF14784, whol...    68   6e-10
UniRef50_Q21L63 Cluster: Dihydrouridine synthase, DuS; n=1; Sacc...    68   6e-10
UniRef50_A4BWB1 Cluster: Putative uncharacterized protein; n=5; ...    68   6e-10
UniRef50_Q7VKU5 Cluster: tRNA-dihydrouridine synthase C; n=118; ...    68   6e-10
UniRef50_UPI00015B40A4 Cluster: PREDICTED: similar to tRNA-dihyd...    68   8e-10
UniRef50_A2DYY3 Cluster: Putative uncharacterized protein; n=1; ...    68   8e-10
UniRef50_Q57V78 Cluster: TRNA-dihydrouridine synthase 1, putativ...    67   1e-09
UniRef50_O31546 Cluster: Probable tRNA-dihydrouridine synthase 2...    67   1e-09
UniRef50_UPI000023EA9A Cluster: hypothetical protein FG07217.1; ...    67   1e-09
UniRef50_Q6MNE4 Cluster: Dihydrouridine synthase family protein;...    67   1e-09
UniRef50_Q583Y8 Cluster: TRNA-dihydrouridine synthase 4, putativ...    67   1e-09
UniRef50_A2F0D1 Cluster: Putative uncharacterized protein; n=1; ...    66   3e-09
UniRef50_A1AT39 Cluster: Dihydrouridine synthase, DuS; n=7; Desu...    65   4e-09
UniRef50_Q09504 Cluster: Uncharacterized tRNA-dihydrouridine syn...    65   6e-09
UniRef50_A4BCJ5 Cluster: NifR3/Smm1 family protein; n=2; Gammapr...    64   8e-09
UniRef50_A2FU21 Cluster: Putative uncharacterized protein; n=1; ...    64   1e-08
UniRef50_Q22A31 Cluster: TIM-barrel protein, yjbN family; n=1; T...    63   2e-08
UniRef50_Q550J6 Cluster: Putative uncharacterized protein; n=2; ...    63   2e-08
UniRef50_Q5KGP0 Cluster: Putative uncharacterized protein; n=3; ...    62   3e-08
UniRef50_A7EMF2 Cluster: Putative uncharacterized protein; n=1; ...    62   4e-08
UniRef50_A2ACC0 Cluster: Novel protein; n=17; Eumetazoa|Rep: Nov...    61   7e-08
UniRef50_Q4UGK9 Cluster: Putative uncharacterized protein; n=2; ...    61   7e-08
UniRef50_Q4PAE4 Cluster: Putative uncharacterized protein; n=1; ...    61   7e-08
UniRef50_Q5SMC7 Cluster: TRNA-dihydrouridine synthase; n=2; Ther...    60   2e-07
UniRef50_Q83D40 Cluster: TIM-barrel protein, yjbN family; n=7; B...    60   2e-07
UniRef50_Q4FQ57 Cluster: Possible tRNA-dihydrouridine synthase; ...    59   3e-07
UniRef50_A4RU69 Cluster: Predicted protein; n=2; Ostreococcus|Re...    58   5e-07
UniRef50_Q3IKP0 Cluster: TRNA-dihydrouridine synthase C; n=5; Al...    58   9e-07
UniRef50_A5Z3X7 Cluster: Putative uncharacterized protein; n=1; ...    57   1e-06
UniRef50_Q4PBU9 Cluster: Putative uncharacterized protein; n=1; ...    56   2e-06
UniRef50_Q97DM0 Cluster: Predicted TIM-barrel enzyme, nifR3 fami...    56   3e-06
UniRef50_Q7R1J1 Cluster: GLP_38_15456_16676; n=1; Giardia lambli...    56   3e-06
UniRef50_A1IED4 Cluster: Putative uncharacterized protein; n=1; ...    56   4e-06
UniRef50_A0EAZ6 Cluster: Chromosome undetermined scaffold_87, wh...    56   4e-06
UniRef50_UPI0000DAE45A Cluster: hypothetical protein Rgryl_01000...    55   5e-06
UniRef50_Q4FLD8 Cluster: Putative uncharacterized protein; n=2; ...    55   5e-06
UniRef50_A2DHB4 Cluster: Putative uncharacterized protein; n=1; ...    55   5e-06
UniRef50_Q7R9R0 Cluster: Uncharacterized protein family UPF0034,...    54   8e-06
UniRef50_A5WG83 Cluster: TIM-barrel protein, yjbN family; n=4; M...    54   1e-05
UniRef50_Q04VP3 Cluster: TRNA-dihydrouridine synthase; n=4; Lept...    53   2e-05
UniRef50_Q4Q391 Cluster: Putative uncharacterized protein; n=3; ...    53   2e-05
UniRef50_Q9PGB5 Cluster: tRNA-dihydrouridine synthase A; n=8; Pr...    53   2e-05
UniRef50_A2EN54 Cluster: Putative uncharacterized protein; n=1; ...    53   2e-05
UniRef50_Q5ZVH8 Cluster: Zinc binding TIM barrel protein, YjbN f...    52   4e-05
UniRef50_A6GGZ7 Cluster: Putative uncharacterized protein; n=2; ...    52   4e-05
UniRef50_A1RNI1 Cluster: TIM-barrel protein, yjbN family; n=30; ...    52   6e-05
UniRef50_Q6BX60 Cluster: Debaryomyces hansenii chromosome B of s...    52   6e-05
UniRef50_A6RW05 Cluster: Putative uncharacterized protein; n=1; ...    52   6e-05
UniRef50_O51243 Cluster: Putative uncharacterized protein BB0225...    51   8e-05
UniRef50_Q0VPD7 Cluster: TIM-barrel protein, yjbN family; n=4; B...    51   8e-05
UniRef50_A7DKP5 Cluster: Dihydrouridine synthase, DuS; n=2; Meth...    51   1e-04
UniRef50_Q6C002 Cluster: Yarrowia lipolytica chromosome F of str...    51   1e-04
UniRef50_A2EF32 Cluster: Dihydrouridine synthase, putative; n=1;...    50   1e-04
UniRef50_A6RVN2 Cluster: Putative uncharacterized protein; n=2; ...    50   1e-04
UniRef50_A6U9Y2 Cluster: Dihydrouridine synthase DuS; n=2; Sinor...    50   2e-04
UniRef50_Q7R3H4 Cluster: GLP_158_49916_51304; n=1; Giardia lambl...    50   2e-04
UniRef50_A5GPV9 Cluster: TRNA-dihydrouridine synthase A; n=21; C...    49   3e-04
UniRef50_Q7UBC5 Cluster: tRNA-dihydrouridine synthase A; n=231; ...    49   3e-04
UniRef50_A7AWB5 Cluster: Dihydrouridine synthase (Dus) domain co...    47   0.001
UniRef50_A4SY29 Cluster: Dihydrouridine synthase, DuS; n=1; Poly...    46   0.002
UniRef50_A3AVU4 Cluster: Putative uncharacterized protein; n=1; ...    46   0.003
UniRef50_P96192 Cluster: tRNA-dihydrouridine synthase C; n=1; Az...    46   0.004
UniRef50_A1AW94 Cluster: TIM-barrel protein, yjbN family; n=1; C...    45   0.005
UniRef50_Q59YG4 Cluster: Potential tRNA dihydrouridine synthase;...    45   0.005
UniRef50_A2QES0 Cluster: Contig An02c0390, complete genome; n=12...    45   0.005
UniRef50_O51679 Cluster: Histidine phosphokinase/phophatase, put...    45   0.007
UniRef50_UPI000150A3F7 Cluster: hypothetical protein TTHERM_0014...    44   0.011
UniRef50_Q4PIC3 Cluster: Putative uncharacterized protein; n=1; ...    44   0.011
UniRef50_O32363 Cluster: NifR3-like protein; n=17; Campylobacter...    43   0.020
UniRef50_A5EXU5 Cluster: TRNA-dihydrouridine synthase A; n=1; Di...    43   0.020
UniRef50_UPI000023CFE7 Cluster: hypothetical protein FG01258.1; ...    43   0.026
UniRef50_Q8I3B2 Cluster: Putative uncharacterized protein PFI017...    42   0.046
UniRef50_Q2H6D9 Cluster: Putative uncharacterized protein; n=1; ...    42   0.046
UniRef50_Q5LQV9 Cluster: TRNA-dihydrouridine synthase A; n=46; B...    42   0.061
UniRef50_Q7R8B0 Cluster: Transcription factor iiib 70 kDa subuni...    42   0.061
UniRef50_Q4YRY8 Cluster: Putative uncharacterized protein; n=2; ...    42   0.061
UniRef50_Q8IB84 Cluster: Putative uncharacterized protein MAL8P1...    41   0.081
UniRef50_A5K2C4 Cluster: Phosphatidylcholine-sterol acyltransfer...    41   0.081
UniRef50_P53720 Cluster: tRNA-dihydrouridine synthase 2; n=7; Sa...    41   0.081
UniRef50_UPI0000E472BC Cluster: PREDICTED: similar to tRNA-dihyd...    41   0.11 
UniRef50_Q755E8 Cluster: AFL125Wp; n=1; Eremothecium gossypii|Re...    41   0.11 
UniRef50_Q1DPY5 Cluster: Putative uncharacterized protein; n=1; ...    41   0.11 
UniRef50_A4S469 Cluster: Predicted protein; n=2; Ostreococcus|Re...    40   0.19 
UniRef50_UPI00004991CC Cluster: hypothetical protein 205.t00005;...    40   0.25 
UniRef50_Q5CYL0 Cluster: CDC68 like aminopeptidase family chroma...    40   0.25 
UniRef50_Q24833 Cluster: Putative nitrogen fixation regulatory p...    40   0.25 
UniRef50_A7EHJ6 Cluster: Putative uncharacterized protein; n=2; ...    40   0.25 
UniRef50_O04650 Cluster: A_TM021B04.7 protein; n=2; Arabidopsis ...    39   0.33 
UniRef50_Q7RI83 Cluster: CCAAT-box DNA binding protein subunit B...    39   0.33 
UniRef50_A2FDS6 Cluster: Variable membrane protein, putative; n=...    39   0.33 
UniRef50_A2EAT7 Cluster: Putative uncharacterized protein; n=1; ...    39   0.33 
UniRef50_Q4A6U3 Cluster: Putative uncharacterized protein; n=2; ...    39   0.43 
UniRef50_Q31C98 Cluster: Putative uncharacterized protein precur...    39   0.43 
UniRef50_Q54J63 Cluster: C2H2 type Zn finger-containing protein;...    39   0.43 
UniRef50_Q2LEB7 Cluster: Jacob 6; n=3; Entamoeba invadens|Rep: J...    39   0.43 
UniRef50_UPI00006CCCD3 Cluster: hypothetical protein TTHERM_0033...    38   0.57 
UniRef50_UPI0000586CAD Cluster: PREDICTED: similar to Dus1l prot...    38   0.75 
UniRef50_UPI000049A33F Cluster: hypothetical protein 476.t00003;...    38   0.75 
UniRef50_Q9LH98 Cluster: Arabidopsis thaliana genomic DNA, chrom...    38   0.75 
UniRef50_Q23AJ7 Cluster: Cyclic nucleotide-binding domain contai...    38   0.75 
UniRef50_UPI00006CCA52 Cluster: TPR Domain containing protein; n...    38   0.99 
UniRef50_Q7RLZ5 Cluster: CCAAT-box DNA binding protein subunit B...    38   0.99 
UniRef50_Q7RBU8 Cluster: Putative uncharacterized protein PY0603...    38   0.99 
UniRef50_Q54PB2 Cluster: RNA-binding region-containing protein; ...    38   0.99 
UniRef50_Q8STA9 Cluster: UPF0329 protein ECU05_1680/ECU11_0050; ...    38   0.99 
UniRef50_UPI0001509D27 Cluster: PHD-finger family protein; n=1; ...    37   1.3  
UniRef50_UPI00004D6F7D Cluster: formin-like 2; n=3; Euteleostomi...    37   1.3  
UniRef50_Q185D8 Cluster: Putative uncharacterized protein; n=2; ...    37   1.3  
UniRef50_Q8IB22 Cluster: Putative uncharacterized protein MAL8P1...    37   1.3  
UniRef50_Q5CG46 Cluster: Uncharacterized protein family UPF0034;...    37   1.3  
UniRef50_Q4YYI6 Cluster: Ubiquitin-like protein, putative; n=3; ...    37   1.3  
UniRef50_A0DRF5 Cluster: Chromosome undetermined scaffold_60, wh...    37   1.3  
UniRef50_A0CXA4 Cluster: Chromosome undetermined scaffold_30, wh...    37   1.3  
UniRef50_UPI00015B4E97 Cluster: PREDICTED: similar to conserved ...    37   1.7  
UniRef50_UPI0000E49283 Cluster: PREDICTED: hypothetical protein;...    37   1.7  
UniRef50_UPI0000D57222 Cluster: PREDICTED: similar to Transcript...    37   1.7  
UniRef50_Q9LW95 Cluster: KED; n=3; cellular organisms|Rep: KED -...    37   1.7  
UniRef50_Q8IDG7 Cluster: Putative uncharacterized protein PF13_0...    37   1.7  
UniRef50_Q7RFV6 Cluster: GAF domain protein-related; n=1; Plasmo...    37   1.7  
UniRef50_Q7RDM0 Cluster: Putative HSP protein; n=9; Plasmodium|R...    37   1.7  
UniRef50_Q7RCW6 Cluster: CCAAT-box DNA binding protein subunit B...    37   1.7  
UniRef50_Q7RBF2 Cluster: Guanylyl cyclase; n=2; Plasmodium (Vinc...    37   1.7  
UniRef50_Q54Y92 Cluster: Developmental protein; n=2; Dictyosteli...    37   1.7  
UniRef50_Q4Y6I2 Cluster: Putative uncharacterized protein; n=4; ...    37   1.7  
UniRef50_A2FK59 Cluster: Putative uncharacterized protein; n=1; ...    37   1.7  
UniRef50_A2EQX6 Cluster: Putative uncharacterized protein; n=1; ...    37   1.7  
UniRef50_A2DRG2 Cluster: Putative uncharacterized protein; n=1; ...    37   1.7  
UniRef50_Q5AFB2 Cluster: Putative uncharacterized protein UBR1; ...    37   1.7  
UniRef50_UPI0000DA2A7E Cluster: PREDICTED: hypothetical protein;...    36   2.3  
UniRef50_UPI00006CFFAC Cluster: hypothetical protein TTHERM_0072...    36   2.3  
UniRef50_UPI0000499FFB Cluster: hypothetical protein 144.t00010;...    36   2.3  
UniRef50_Q74RB1 Cluster: Putative uncharacterized protein; n=17;...    36   2.3  
UniRef50_Q8IKY2 Cluster: Transcription factor IIIb subunit, puta...    36   2.3  
UniRef50_Q7RNH1 Cluster: Putative uncharacterized protein PY0184...    36   2.3  
UniRef50_Q54KW8 Cluster: Putative uncharacterized protein; n=2; ...    36   2.3  
UniRef50_Q4Z5M6 Cluster: Putative uncharacterized protein; n=1; ...    36   2.3  
UniRef50_Q4YUL1 Cluster: Putative uncharacterized protein; n=1; ...    36   2.3  
UniRef50_A7RJ77 Cluster: Predicted protein; n=1; Nematostella ve...    36   2.3  
UniRef50_A2DSC7 Cluster: Zinc finger, C2H2 type family protein; ...    36   2.3  
UniRef50_Q6C1L3 Cluster: Similar to DEHA0C12419g Debaryomyces ha...    36   2.3  
UniRef50_UPI0000E4938D Cluster: PREDICTED: similar to DnaJ domai...    36   3.0  
UniRef50_UPI0000D56108 Cluster: PREDICTED: similar to CG18304-PA...    36   3.0  
UniRef50_Q8I3L3 Cluster: Putative uncharacterized protein PFE125...    36   3.0  
UniRef50_Q8I311 Cluster: Putative uncharacterized protein PFI069...    36   3.0  
UniRef50_Q7RAX9 Cluster: Putative uncharacterized protein PY0637...    36   3.0  
UniRef50_Q24FF9 Cluster: Putative uncharacterized protein; n=2; ...    36   3.0  
UniRef50_A3FQA8 Cluster: ORF 73, contains large complex repeat C...    36   3.0  
UniRef50_A2EBQ3 Cluster: Retinitis pigmentosa GTPase regulator-l...    36   3.0  
UniRef50_A2EAT9 Cluster: Putative uncharacterized protein; n=1; ...    36   3.0  
UniRef50_A0DQB8 Cluster: Chromosome undetermined scaffold_6, who...    36   3.0  
UniRef50_A6RVV6 Cluster: Predicted protein; n=1; Botryotinia fuc...    36   3.0  
UniRef50_A6UP05 Cluster: Putative uncharacterized protein; n=1; ...    36   3.0  
UniRef50_UPI0000DB76E7 Cluster: PREDICTED: similar to activating...    36   4.0  
UniRef50_UPI00006CFCA0 Cluster: 50S ribosomal protein; n=1; Tetr...    36   4.0  
UniRef50_UPI00006CFC2B Cluster: hypothetical protein TTHERM_0053...    36   4.0  
UniRef50_UPI00006CAF0F Cluster: hypothetical protein TTHERM_0068...    36   4.0  
UniRef50_Q9U380 Cluster: Putative uncharacterized protein; n=2; ...    36   4.0  
UniRef50_Q8I4Y4 Cluster: Putative uncharacterized protein; n=4; ...    36   4.0  
UniRef50_Q8I3X5 Cluster: Putative uncharacterized protein PFE065...    36   4.0  
UniRef50_Q6LF09 Cluster: Putative uncharacterized protein; n=6; ...    36   4.0  
UniRef50_Q5WRA3 Cluster: Multidrug resistance associated protein...    36   4.0  
UniRef50_Q54IN6 Cluster: Putative uncharacterized protein; n=1; ...    36   4.0  
UniRef50_Q23DY9 Cluster: Cation channel family protein; n=2; Alv...    36   4.0  
UniRef50_Q22VV7 Cluster: CHY zinc finger family protein; n=1; Te...    36   4.0  
UniRef50_A2EVM3 Cluster: Viral A-type inclusion protein, putativ...    36   4.0  
UniRef50_A2DCZ8 Cluster: Putative uncharacterized protein; n=1; ...    36   4.0  
UniRef50_A0DA99 Cluster: Chromosome undetermined scaffold_43, wh...    36   4.0  
UniRef50_Q8X0W5 Cluster: Related to micromolar calcium activated...    36   4.0  
UniRef50_Q06704 Cluster: Golgin IMH1; n=2; Saccharomyces cerevis...    36   4.0  
UniRef50_UPI00015B62AB Cluster: PREDICTED: similar to CG18255-PA...    35   5.3  
UniRef50_UPI00015B4683 Cluster: PREDICTED: similar to step ii sp...    35   5.3  
UniRef50_UPI0000D5659A Cluster: PREDICTED: similar to CG31716-PA...    35   5.3  
UniRef50_UPI00006D0E10 Cluster: hypothetical protein TTHERM_0007...    35   5.3  
UniRef50_UPI0000587834 Cluster: PREDICTED: hypothetical protein;...    35   5.3  
UniRef50_Q9CDR2 Cluster: Putative uncharacterized protein ywdA; ...    35   5.3  
UniRef50_Q4FME1 Cluster: Para-aminobenzoate synthase component I...    35   5.3  
UniRef50_A2BXV3 Cluster: Putative uncharacterized protein; n=1; ...    35   5.3  
UniRef50_Q0JLT4 Cluster: Os01g0572100 protein; n=4; Oryza sativa...    35   5.3  
UniRef50_Q01CM9 Cluster: CCCH-type Zn-finger protein; n=2; Ostre...    35   5.3  
UniRef50_Q8ILI4 Cluster: Putative uncharacterized protein; n=1; ...    35   5.3  
UniRef50_Q54J55 Cluster: Myb domain-containing protein; n=1; Dic...    35   5.3  
UniRef50_Q54DW3 Cluster: Putative uncharacterized protein; n=1; ...    35   5.3  
UniRef50_Q4Q669 Cluster: Dihydrouridine synthase (Dus), putative...    35   5.3  
UniRef50_Q23K98 Cluster: Cation channel family protein; n=1; Tet...    35   5.3  
UniRef50_Q23CY3 Cluster: Putative uncharacterized protein; n=1; ...    35   5.3  
UniRef50_Q17IV5 Cluster: Chromodomain helicase DNA binding prote...    35   5.3  
UniRef50_A2FNC4 Cluster: Variable membrane protein, putative; n=...    35   5.3  
UniRef50_A2FK26 Cluster: Putative uncharacterized protein; n=1; ...    35   5.3  
UniRef50_A2FJY0 Cluster: Putative uncharacterized protein; n=1; ...    35   5.3  
UniRef50_A2DU96 Cluster: Putative uncharacterized protein; n=1; ...    35   5.3  
UniRef50_Q6CS59 Cluster: Kluyveromyces lactis strain NRRL Y-1140...    35   5.3  
UniRef50_Q9UTK5 Cluster: Abnormal long morphology protein 1; n=1...    35   5.3  
UniRef50_UPI00015B4A86 Cluster: PREDICTED: similar to conserved ...    35   7.0  
UniRef50_UPI0000E490A6 Cluster: PREDICTED: hypothetical protein;...    35   7.0  
UniRef50_UPI0000D56C7E Cluster: PREDICTED: similar to 39 kDa FK5...    35   7.0  
UniRef50_UPI00006CB399 Cluster: DnaJ domain containing protein; ...    35   7.0  
UniRef50_UPI000069F7BF Cluster: UPI000069F7BF related cluster; n...    35   7.0  
UniRef50_Q4V8V0 Cluster: Zgc:114130; n=2; Danio rerio|Rep: Zgc:1...    35   7.0  
UniRef50_Q4UL48 Cluster: Putative uncharacterized protein; n=6; ...    35   7.0  
UniRef50_Q4HEJ9 Cluster: Alpha-2,3-sialyltransferase; n=1; Campy...    35   7.0  
UniRef50_A6DTT4 Cluster: Putative ABC transporter ATP-binding pr...    35   7.0  
UniRef50_Q8I5K9 Cluster: Putative uncharacterized protein; n=6; ...    35   7.0  
UniRef50_Q8I1P2 Cluster: Putative uncharacterized protein PFD094...    35   7.0  
UniRef50_Q86AP2 Cluster: Similar to Plasmodium falciparum. Splic...    35   7.0  
UniRef50_Q7RGK0 Cluster: Putative uncharacterized protein PY0434...    35   7.0  
UniRef50_Q54BM0 Cluster: Putative uncharacterized protein; n=1; ...    35   7.0  
UniRef50_Q4XNR6 Cluster: Putative uncharacterized protein; n=1; ...    35   7.0  
UniRef50_Q4XNC6 Cluster: Putative uncharacterized protein; n=3; ...    35   7.0  
UniRef50_Q24DC4 Cluster: Transporter/monovalent cation:proton an...    35   7.0  
UniRef50_Q23DS1 Cluster: GTP-binding protein, putative; n=2; Euk...    35   7.0  
UniRef50_Q236Y1 Cluster: Nucleolar protein,Nop52 containing prot...    35   7.0  
UniRef50_Q22TK4 Cluster: Putative uncharacterized protein; n=1; ...    35   7.0  
UniRef50_A7RXM0 Cluster: Predicted protein; n=1; Nematostella ve...    35   7.0  
UniRef50_A2FQ26 Cluster: Putative uncharacterized protein; n=1; ...    35   7.0  
UniRef50_A2DGN0 Cluster: Viral A-type inclusion protein, putativ...    35   7.0  
UniRef50_A0C765 Cluster: Chromosome undetermined scaffold_154, w...    35   7.0  
UniRef50_A6RSH0 Cluster: Putative uncharacterized protein; n=2; ...    35   7.0  
UniRef50_P26651 Cluster: Tristetraproline; n=15; Eutheria|Rep: T...    35   7.0  
UniRef50_Q20085 Cluster: Membrane-associated tyrosine- and threo...    35   7.0  
UniRef50_UPI0000E4A60A Cluster: PREDICTED: hypothetical protein;...    34   9.3  
UniRef50_UPI0000DB7261 Cluster: PREDICTED: similar to CG18304-PA...    34   9.3  
UniRef50_UPI00006CD8C0 Cluster: hypothetical protein TTHERM_0052...    34   9.3  
UniRef50_UPI0000519A67 Cluster: PREDICTED: similar to Calcium-bi...    34   9.3  
UniRef50_UPI000065D2BF Cluster: Homolog of Homo sapiens "HT017; ...    34   9.3  
UniRef50_Q7UWL4 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_Q7P5Y3 Cluster: Chromosomal replication initiator prote...    34   9.3  
UniRef50_Q4ZHU1 Cluster: Biofilm-associated protein; n=7; Staphy...    34   9.3  
UniRef50_Q1FF30 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_Q119V0 Cluster: Peptidase M23B; n=1; Trichodesmium eryt...    34   9.3  
UniRef50_A5MYZ5 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_Q00VG0 Cluster: Homology to unknown gene; n=1; Ostreoco...    34   9.3  
UniRef50_Q8IEC5 Cluster: Putative uncharacterized protein PF13_0...    34   9.3  
UniRef50_Q7RP00 Cluster: Arabidopsis thaliana MXI22.1-related; n...    34   9.3  
UniRef50_Q7RNC6 Cluster: KED, putative; n=3; Plasmodium (Vinckei...    34   9.3  
UniRef50_Q7R9A9 Cluster: Drosophila melanogaster CG15040 gene pr...    34   9.3  
UniRef50_Q6LF58 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_Q616H4 Cluster: Putative uncharacterized protein CBG152...    34   9.3  
UniRef50_Q55AJ7 Cluster: Putative uncharacterized protein; n=2; ...    34   9.3  
UniRef50_Q4Z510 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_Q23WL4 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_Q23FP7 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_Q23DL3 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_Q23AJ8 Cluster: Cyclic nucleotide-binding domain contai...    34   9.3  
UniRef50_Q233W7 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_Q228K2 Cluster: SNF2 family N-terminal domain containin...    34   9.3  
UniRef50_Q1ZXA6 Cluster: DNA repair protein Rad4 family protein;...    34   9.3  
UniRef50_Q16WE5 Cluster: Translation initiation factor if-2; n=1...    34   9.3  
UniRef50_O96179 Cluster: Putative uncharacterized protein PFB042...    34   9.3  
UniRef50_A2EVV5 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_A2E8X0 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_A2DC69 Cluster: Glutamic acid-rich protein, putative; n...    34   9.3  
UniRef50_A2DAK5 Cluster: Putative uncharacterized protein; n=1; ...    34   9.3  
UniRef50_A0E9E1 Cluster: Chromosome undetermined scaffold_84, wh...    34   9.3  
UniRef50_A0CMI7 Cluster: Chromosome undetermined scaffold_21, wh...    34   9.3  
UniRef50_A0BVF0 Cluster: Chromosome undetermined scaffold_13, wh...    34   9.3  
UniRef50_Q0TYL7 Cluster: Putative uncharacterized protein; n=2; ...    34   9.3  
UniRef50_A6RH89 Cluster: Predicted protein; n=2; Ajellomyces cap...    34   9.3  
UniRef50_A3LZ88 Cluster: Myosin-1; n=1; Pichia stipitis|Rep: Myo...    34   9.3  
UniRef50_Q12499 Cluster: Nucleolar protein NOP58; n=5; Eukaryota...    34   9.3  

>UniRef50_Q17M24 Cluster: tRNA-dihydrouridine synthase; n=1; Aedes
           aegypti|Rep: tRNA-dihydrouridine synthase - Aedes
           aegypti (Yellowfever mosquito)
          Length = 578

 Score =  643 bits (1589), Expect = 0.0
 Identities = 298/588 (50%), Positives = 408/588 (69%), Gaps = 18/588 (3%)

Query: 8   VCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKNDSKTKK 67
           VC IK E+++ +   ++E     EK+  D + A+  DN  E    K    + + D K K 
Sbjct: 5   VCYIKPEFLVPR---VQE-----EKKPEDVTPAAKADNGTEEPPAK----KGRFDKKKKN 52

Query: 68  RGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFLNSKPKDIGDQ 127
           RGQNK+R   FK+  +++ C T+LD + + +   C    C+F HD ++F+  KPKDIG+ 
Sbjct: 53  RGQNKNRDLPFKEQDDARLCKTLLDGKLNSEK--CSNPRCRFSHDLERFIQLKPKDIGES 110

Query: 128 CHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTKNTLQPSLQTQLQKKKY 187
           C++Y ++G C  G+ CR+   H+  +  N ++     +  +     L   LQ QL+KK Y
Sbjct: 111 CYIYSLKGYCNFGVTCRFAGAHLDEESNNKISEGIKREDHNLVSMCLSFDLQNQLRKKSY 170

Query: 188 NFDLAEKLVKHLDTRNKSVDKNLN-TSADVGEDIKIGAVTDEDLIKLLPRERKTIDWNNK 246
           N+  A K++   +   K   + ++   +D  +   IG+ TDEDL+KL   ERK I++ +K
Sbjct: 171 NYSKANKIISKFERLQKESKEEVDGLGSDTLKAKPIGSCTDEDLVKLRSPERKKINFKDK 230

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           LYLSPLTTVGNLPFRRICKE+G D+TCGEMA    ++ G+ QEWAL KRH +EDLFG QI
Sbjct: 231 LYLSPLTTVGNLPFRRICKEYGVDITCGEMACSVPIINGMMQEWALTKRHPSEDLFGVQI 290

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
           CG+N  +++   Q++ E+ ++DF+DLN+GCPIDLI+ +GGGS ++ R   LE  ++  S+
Sbjct: 291 CGHNQKLVSYATQVIAEHADVDFVDLNLGCPIDLIFNQGGGSALLRRRNILEVMIQSCSR 350

Query: 367 LLSI---PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
           +L+     FTVK R G+Y +K + H +VPK   WGASL+T+HGR++E RYTK +DW+YI 
Sbjct: 351 ILADYDKEFTVKTRMGIYANKYVAHELVPKFEEWGASLVTIHGRTKEQRYTKKADWDYIR 410

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDI 483
            CAQ A   P+YGNGDIF Y+DY++ ++ AP + GVM+GRGALIKPW+F EIKEQK  D 
Sbjct: 411 QCAQQAKSIPIYGNGDIFCYQDYLDAKERAPELAGVMVGRGALIKPWVFQEIKEQKNLDP 470

Query: 484 SSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINER 543
           SS +R ++LK+Y NYGLEHWGSDT+GVE+TRRFLLEW SFLYRYVP GLLERPPQ+IN+R
Sbjct: 471 SSSERMDMLKRYVNYGLEHWGSDTKGVENTRRFLLEWQSFLYRYVPSGLLERPPQKINQR 530

Query: 544 PPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591
           P  + GRDDLETLMAS NC+DW+K+SEMLLGPVPD F F+PKHKANSY
Sbjct: 531 PEAFRGRDDLETLMASPNCSDWVKLSEMLLGPVPDSFNFVPKHKANSY 578


>UniRef50_Q7PVV7 Cluster: ENSANGP00000016833; n=2;
           Endopterygota|Rep: ENSANGP00000016833 - Anopheles
           gambiae str. PEST
          Length = 594

 Score =  641 bits (1583), Expect = 0.0
 Identities = 315/603 (52%), Positives = 403/603 (66%), Gaps = 30/603 (4%)

Query: 7   GVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIE-ITEDKNDSKT 65
           G+C IK E+++ +   IE K+   E  K+D++S   +      KK ++E   E+    K 
Sbjct: 4   GICHIKAEFLIPR---IEGKA---EDAKVDDTSEPPE------KKGRMEGNAEEPQGKKK 51

Query: 66  KKRGQNKSRPKIFKDGKESKPCPTILDVESSEQL-KICQYNNCKFIHDSKQFLNSKPKDI 124
           K RGQNKSR   FK+    + C ++LD    E   K C   NC+F HD  +FL  KPKDI
Sbjct: 52  KNRGQNKSRTVPFKEEDGLRLCKSLLDGNLGEDAAKKCTNANCRFSHDLDKFLQLKPKDI 111

Query: 125 GDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTKNTLQPSLQTQLQK 184
              C++Y  +G C  G+ CR+   H+  +  NI   +            L   LQ  L+K
Sbjct: 112 DGTCYIYSTKGYCNFGVTCRFAGAHLDENRRNIYPEDFKPDTSMLVSTWLSTDLQHILRK 171

Query: 185 KKYNFDLAEKLVKHLDT-----RNKSVDKNLNTSADVGEDIK--------IGAVTDEDLI 231
           +KYNF+ + K+V   D      +N+    N   + +  +D +         GAVTDED+I
Sbjct: 172 RKYNFNKSTKIVNKFDRLQQEEKNEKAKSNEQENGEAKDDAEQKPEESKPAGAVTDEDVI 231

Query: 232 KLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWA 291
           KL   ERK I + +KLYLSPLTTVGNLPFRRICKE+G D+TCGEMA    ++ G  QEWA
Sbjct: 232 KLRSAERKRIVFRDKLYLSPLTTVGNLPFRRICKEYGVDITCGEMACAIPIINGAIQEWA 291

Query: 292 LVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM 351
           L KRH +EDLFG Q+CG+NP ++T  AQ++ E  ++DFIDLN GCPIDLI+ +GGGS ++
Sbjct: 292 LTKRHSSEDLFGVQLCGHNPKLVTYAAQIIAEKADVDFIDLNTGCPIDLIFNQGGGSALL 351

Query: 352 HRLPALETSVRCASKLLSI---PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRS 408
            R   L+  V+  S+LL+     FTVK R G+Y +K I H +VPK  +WGASLIT+HGR+
Sbjct: 352 RRQNVLKVMVQSCSRLLADYGKEFTVKTRIGIYNNKLIAHEMVPKFEDWGASLITIHGRT 411

Query: 409 REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIK 468
           +E RYTK +DWEY++ CA  A   PV+GNGDIF YEDY  +R   P + GVM+GRGALIK
Sbjct: 412 KEQRYTKRADWEYLQQCATQAQSVPVFGNGDIFGYEDYEHIRTKCPNIAGVMVGRGALIK 471

Query: 469 PWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYV 528
           PW+F EIKE+K  D SS +RFE+LK+Y NYGLEHWGSDT+GVE+TRRFLLEW SFLYRYV
Sbjct: 472 PWVFQEIKERKTLDPSSGERFEMLKRYVNYGLEHWGSDTKGVETTRRFLLEWQSFLYRYV 531

Query: 529 PVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKA 588
           P GLLERPPQRINERP  Y GRDDLETLMAS NC DW+K+SEMLLGPVP+GF F+PKHKA
Sbjct: 532 PYGLLERPPQRINERPDAYRGRDDLETLMASPNCNDWVKLSEMLLGPVPEGFNFVPKHKA 591

Query: 589 NSY 591
           N+Y
Sbjct: 592 NAY 594


>UniRef50_A7S213 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 570

 Score =  620 bits (1531), Expect = e-176
 Identities = 299/540 (55%), Positives = 379/540 (70%), Gaps = 17/540 (3%)

Query: 55  EITEDKNDSKTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSK 114
           E T+     K K RG N+ RP+  +    SK C      E   +   C Y      HD +
Sbjct: 40  EHTDGPPRKKKKNRGMNRQRPRDQRPDNSSKLCSFAARGEECTRGDSCFYG-----HDPQ 94

Query: 115 QFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTKNTL 174
           +FL +K  DIG +C  +   GKCP GI+CRY   H TAD  +I+N E F  +K+DT N L
Sbjct: 95  KFLETKEPDIGKECVNFLKSGKCPYGISCRYWKHHTTADLKSIINEEFFSHYKEDTSNNL 154

Query: 175 QPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGEDIKIGAVTDEDLIKLL 234
              +Q  L+KKKY F  +   ++ L        +N+NT   V      G VT+EDLIKL 
Sbjct: 155 AKDVQISLRKKKYMFPRSNAYLELLSNA-----QNVNTQTGVVRTH--GCVTNEDLIKLR 207

Query: 235 PRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVK 294
            +E+K ID+++KLYL+PLTT+GNLPFRRICK++GAD+TCGEMA+C +LL+G + EWALVK
Sbjct: 208 TQEKKRIDFSDKLYLAPLTTIGNLPFRRICKQYGADITCGEMAMCTNLLQGQQSEWALVK 267

Query: 295 RHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRL 354
           RH +ED+FG Q+CG  P  +TK A+LLQ+ T++DFID+N GCPIDL++ KG GS +M R 
Sbjct: 268 RHSSEDIFGVQLCGAFPDTMTKCAELLQKETDVDFIDINTGCPIDLVFNKGAGSALMERK 327

Query: 355 PALETSVRCASKLLSIPFTVKMRTGVYQDKKIT---HTIVPKMSNWGASLITVHGRSREA 411
             L+  V+    ++ IP TVK+R G++ DKK T   H +V  + +WG  ++T+HGRSRE 
Sbjct: 328 GKLQQIVQGMKSVIDIPLTVKIRAGIH-DKKYTWNAHKLVGNLRDWGTDMVTIHGRSREQ 386

Query: 412 RYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWI 471
           RYTKS+DW+YI   A+ A+P PV+GNGDI S+ED ++ RK A  V GVMI RGA+IKPWI
Sbjct: 387 RYTKSADWDYISEVAKLASPMPVFGNGDILSFEDAMQHRKQAG-VAGVMIARGAIIKPWI 445

Query: 472 FNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVG 531
           F EIKEQ+ WDISS +R +IL+++ N GLEHWGSDTQGVE TRRFLLEWLSF  RYVPVG
Sbjct: 446 FTEIKEQRHWDISSSERLDILRQFVNAGLEHWGSDTQGVEKTRRFLLEWLSFTCRYVPVG 505

Query: 532 LLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591
           LLER PQRIN+RPP YFGR+DLETLMAS NC DW+KISEMLLGPVP  F FLPKHKANSY
Sbjct: 506 LLERLPQRINDRPPAYFGRNDLETLMASPNCEDWVKISEMLLGPVPTTFAFLPKHKANSY 565


>UniRef50_Q9VIS4 Cluster: CG10463-PA; n=3; Sophophora|Rep:
           CG10463-PA - Drosophila melanogaster (Fruit fly)
          Length = 604

 Score =  606 bits (1497), Expect = e-172
 Identities = 301/617 (48%), Positives = 403/617 (65%), Gaps = 44/617 (7%)

Query: 5   NAGVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKN-DS 63
           ++G+C IK EY++ ++   +  S        D +    +D        ++E  E K  D 
Sbjct: 2   DSGICYIKPEYLVTEA---DGGSAAANTENSDTNKRKREDGG------EVEAGEKKKWDK 52

Query: 64  KTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFLNSKPKD 123
           K +KRGQNK+RP +FKD + S  C +++D    E    C   NC+++HD   +L +K +D
Sbjct: 53  KERKRGQNKNRP-VFKDERYSHLCHSLIDGTGGEP---CSLANCRYVHDLDAYLAAKGED 108

Query: 124 IGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTK-NTLQPSLQTQL 182
           +G +C+VY  +G C RG++CR+   H    G N+  RE +D+    T  N +   LQ +L
Sbjct: 109 LGPECYVYTTKGYCARGVSCRFAKAHTDEQGRNL-KREDYDENAPPTTCNGVSSELQVRL 167

Query: 183 QKKKYNFDLAEKLVKHL----DTRN--KSVDKNLNTSADVGE----------------DI 220
           +K +Y+F  +++L+K      D R   +  +K  N S + GE                D 
Sbjct: 168 RKHEYDFSRSKELIKMAEKLRDARKLKEQQEKEKNPSEETGEKQPSETTEILDAEKQTDT 227

Query: 221 K-----IGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGE 275
           K      G   D+  I      +  +D+  KL LSPLTT+GNLPFRRICKEFGAD+TCGE
Sbjct: 228 KSKPTATGCAIDDSAIGRDADHKPAVDFREKLVLSPLTTLGNLPFRRICKEFGADITCGE 287

Query: 276 MALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIG 335
           MA  + LLKG+ QEWAL KRH++ED+FG Q+CGNNP ++ + AQ++ E  ++DFIDLNIG
Sbjct: 288 MACAQPLLKGMGQEWALTKRHQSEDVFGVQLCGNNPNMLNQAAQVIHETAQVDFIDLNIG 347

Query: 336 CPIDLIYKKGGGSGMMHRLPALETSVR-CASKLLSIPFTVKMRTGVYQDKKITHTIVPKM 394
           CPIDLIY++GGGS +M R   LE +VR CA+    +PFTVKMRTG+Y DK + H ++P +
Sbjct: 348 CPIDLIYQQGGGSALMRRTNILELTVRSCAALSDRLPFTVKMRTGIYADKSVAHELLPLV 407

Query: 395 SNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAP 454
             WGAS +T+HGRSRE RYTK ++W YIE CA  A   PV GNGDI SYEDY+E R +AP
Sbjct: 408 EEWGASAVTLHGRSREQRYTKHANWAYIEECAAKAKCMPVIGNGDILSYEDYMERRTLAP 467

Query: 455 TVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTR 514
            V  VMIGRGALIKPWIF EIKE++ W  SS  R+E+L+K+ NYGLEHWGSDT+GVE+TR
Sbjct: 468 HVCSVMIGRGALIKPWIFQEIKEKQAWSPSSGQRYEMLQKFCNYGLEHWGSDTKGVETTR 527

Query: 515 RFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLG 574
           RFLLEW SFLYRY+P  L   PPQ+IN RP  Y GRD++ETLM+S N  DW+K+SE LLG
Sbjct: 528 RFLLEWQSFLYRYIPEALQTAPPQKINARPQKYRGRDEMETLMSSGNAADWVKLSESLLG 587

Query: 575 PVPDGFQFLPKHKANSY 591
            VP+GF F+PKHKAN++
Sbjct: 588 RVPEGFTFVPKHKANAF 604


>UniRef50_Q96G46 Cluster: tRNA-dihydrouridine synthase 3-like; n=12;
           Eutheria|Rep: tRNA-dihydrouridine synthase 3-like - Homo
           sapiens (Human)
          Length = 650

 Score =  586 bits (1446), Expect = e-166
 Identities = 282/567 (49%), Positives = 383/567 (67%), Gaps = 36/567 (6%)

Query: 55  EITEDKNDSKTKKR--GQNKSRPKIFKDGKE-SKPCPTILDVESSEQLKICQYNN-CKFI 110
           E  E     +T+KR  GQNK RP +     + ++ CP+++   +++    C + + C+F+
Sbjct: 89  EAAEPGEQLQTQKRARGQNKGRPHVKPTNYDKNRLCPSLIQESAAK----CFFGDRCRFL 144

Query: 111 HDSKQFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKD-- 168
           HD  ++L +KP D+G +C +++  G+CP G+ CR+   H+  +G N+V  E   +     
Sbjct: 145 HDVGRYLETKPADLGPRCVLFETFGRCPYGVTCRFAGAHLRPEGQNLVQEELAARGTQPP 204

Query: 169 DTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLD------------TRNKSVDKNLN----- 211
             +N L  +LQ QL+K++  F+ AE+ ++               T  +   +  N     
Sbjct: 205 SIRNGLDKALQQQLRKREVRFERAEQALRRFSQGPTPAAAVPEGTAAEGAPRQENCGAQQ 264

Query: 212 ------TSADVGEDIKI-GAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRIC 264
                 TS      ++  G +TDED+++L P E+K +D   KLYL+PLTT GNLPFRRIC
Sbjct: 265 VPAGPGTSTPPSSPVRTCGPLTDEDVVRLRPCEKKRLDIRGKLYLAPLTTCGNLPFRRIC 324

Query: 265 KEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQEN 324
           K FGADVTCGEMA+C +LL+G   EWAL+KRH+ ED+FG Q+ G  P  +TK A+LL   
Sbjct: 325 KRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGAFPDTMTKCAELLSRT 384

Query: 325 TELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDK 384
            E+DF+D+N+GCPIDL+YKKGGG  +M+R    +  VR  +++L +P TVK+RTGV +  
Sbjct: 385 VEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVRGMNQVLDVPLTVKIRTGVQERV 444

Query: 385 KITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444
            + H ++P++ +WG +L+T+HGRSRE RYTK +DW+YIE C QAA+P P++GNGDI S+E
Sbjct: 445 NLAHRLLPELRDWGVALVTLHGRSREQRYTKLADWQYIEECVQAASPMPLFGNGDILSFE 504

Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWG 504
           D    R +   V G+MI RGAL+KPW+F EIKEQ+ WDISS +R +IL+ ++NYGLEHWG
Sbjct: 505 D--ANRAMQTGVTGIMIARGALLKPWLFTEIKEQRHWDISSSERLDILRDFTNYGLEHWG 562

Query: 505 SDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTD 564
           SDTQGVE TRRFLLEWLSFL RYVPVGLLER PQRINERPP Y GRD LETLMAS    D
Sbjct: 563 SDTQGVEKTRRFLLEWLSFLCRYVPVGLLERLPQRINERPPYYLGRDYLETLMASQKAAD 622

Query: 565 WIKISEMLLGPVPDGFQFLPKHKANSY 591
           WI+ISEMLLGPVP  F FLPKHKAN+Y
Sbjct: 623 WIRISEMLLGPVPPSFAFLPKHKANAY 649


>UniRef50_Q91XI1 Cluster: tRNA-dihydrouridine synthase 3-like; n=7;
           Euteleostomi|Rep: tRNA-dihydrouridine synthase 3-like -
           Mus musculus (Mouse)
          Length = 637

 Score =  583 bits (1439), Expect = e-165
 Identities = 285/575 (49%), Positives = 380/575 (66%), Gaps = 34/575 (5%)

Query: 44  DNNLEFKKTKIEITEDKNDSKTKKRGQNKSRPKIFKDGKESKP--CPTILDVESSEQLKI 101
           ++  E  KT++ I   +     + RGQNKSRP + K     K   CP+ L     E    
Sbjct: 69  EDGQENGKTEVAIESRERQVPKRARGQNKSRPHV-KPAHYDKDRLCPSFLQ----EPATP 123

Query: 102 CQYNN-CKFIHDSKQFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNR 160
           C + + C+F+HD  ++L +KP D+G +C +++  G+CP  + CR+   H+  +G N+V  
Sbjct: 124 CAFGDRCRFLHDVGRYLETKPADLGPRCVLFETFGRCPFSMTCRFAGAHLGPEGQNLVQE 183

Query: 161 EKFDQWKD--DTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLDT----------------- 201
           E   +       +N L  +LQ QL+K++  F+ AE+ +  L                   
Sbjct: 184 EVVARCAQLPSVRNGLDRALQQQLRKRQVCFERAEQALNRLTQSPMPTVVPETTVAMATP 243

Query: 202 RNKSVDKNLNTSADVGEDIK-----IGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVG 256
           +  S    L+T    G          G +TDED+I+L P E+K +D + KLYL+PLTT G
Sbjct: 244 KQNSCHAQLDTVGGAGTPQSSPVPTCGPLTDEDVIRLRPCEKKRLDISGKLYLAPLTTCG 303

Query: 257 NLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITK 316
           NLPFRRICK FGADVTCGEMA+C +LL+G   EWAL+KRH  ED+FG Q+ G  P  +TK
Sbjct: 304 NLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHPCEDIFGVQLEGAFPDTMTK 363

Query: 317 VAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKM 376
            A+LL    ++DF+D+N+GCPIDL+YKKGGG  +M+R    +  VR  + +L +P TVKM
Sbjct: 364 CAELLNRTIDVDFVDINVGCPIDLVYKKGGGCALMNRSAKFQQIVRGVNGVLDVPLTVKM 423

Query: 377 RTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYG 436
           RTGV +   + H ++P++ +WG +L+T+HGRSRE RYT+ +DW YIE CA+ A+P P++G
Sbjct: 424 RTGVQERVSLAHRLLPELRDWGVALVTLHGRSREQRYTRLADWPYIEQCAKVASPMPLFG 483

Query: 437 NGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYS 496
           NGDI S+ED      +   V G+M+ RGAL+KPW+F EIKEQ+ WDISS +R +IL+ ++
Sbjct: 484 NGDILSFED--ANCAMQTGVAGIMVARGALLKPWLFTEIKEQRHWDISSSERLDILRDFT 541

Query: 497 NYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETL 556
           +YGLEHWGSDTQGVE TRRFLLEWLSFL RYVPVGLLERPPQRINERPP Y GRD LETL
Sbjct: 542 HYGLEHWGSDTQGVERTRRFLLEWLSFLCRYVPVGLLERPPQRINERPPYYLGRDYLETL 601

Query: 557 MASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591
           MAS    DWI+ISEMLLGPVP GF FLPKHKAN+Y
Sbjct: 602 MASQQAADWIRISEMLLGPVPPGFVFLPKHKANAY 636


>UniRef50_UPI000058804E Cluster: PREDICTED: similar to MGC53781
           protein; n=3; Deuterostomia|Rep: PREDICTED: similar to
           MGC53781 protein - Strongylocentrotus purpuratus
          Length = 655

 Score =  549 bits (1356), Expect = e-155
 Identities = 283/573 (49%), Positives = 370/573 (64%), Gaps = 52/573 (9%)

Query: 64  KTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNN-CKFIHDSKQFLNSKPK 122
           K K +GQNK R +      E +PC   L          C++ + CKF HD ++ +  K  
Sbjct: 89  KQKGKGQNKKRYREKTVPSEERPCLDFLRGAG------CRFGDKCKFSHDIQKLMAGKAP 142

Query: 123 DIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQW--KDDTKNTLQPSLQT 180
           DI  +C  +   G CP G+ CR+G  HI  +  NIV+ EK  +   K   +N L   LQ 
Sbjct: 143 DINPRCINFDKFGSCPYGMLCRFGGAHIDDNLKNIVDEEKVKETGGKCVVRNLLSKDLQI 202

Query: 181 QLQKKKYNFDLAEKLVKHLDTRNKSVD---------KNLNTSADV-----GEDIK-IGAV 225
           QL+K+  +F  +++ ++ LDTR K  +         K+ N S  V     G+     G V
Sbjct: 203 QLRKRNVHFKKSDQYMRTLDTRKKESNSKRPEGPGCKDHNESPTVVMPTSGDAHNHAGTV 262

Query: 226 TDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKG 285
           TD D+IKL P E+K +D  +KL L+PLTTVGNLPFR +CK+ GAD+TCGEMA+C +LL+G
Sbjct: 263 TDADVIKLRPEEKKKLDVKDKLLLAPLTTVGNLPFRAVCKKLGADITCGEMAMCTNLLQG 322

Query: 286 LKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG 345
              EWAL++RH +ED+FG Q+CG  P  +T+ A+LL +  ++DFID+N+GCPIDL+Y KG
Sbjct: 323 QSSEWALLRRHPSEDIFGVQLCGGFPDTMTRCAELLNDRLDIDFIDINVGCPIDLVYHKG 382

Query: 346 GGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVH 405
            GSG+M+R+   +  VR  S +L IP TVKMRTGV+ D  + H IV ++ +WGAS++TVH
Sbjct: 383 AGSGLMNRMGKFQEIVRGMSSVLDIPLTVKMRTGVHNDNPVAHKIVRRIYDWGASVVTVH 442

Query: 406 GRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465
           GR+RE RY+K +DW+Y++ C QAA P P  GNGDI SYED    R+ +    G MI RGA
Sbjct: 443 GRTREQRYSKLADWDYLKDCVQAADPHPFIGNGDILSYEDSNFFREQSGAT-GQMIARGA 501

Query: 466 LIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLY 525
           LIKPWIF EIKEQ+ WDISS +RF+IL+ Y N GL HWGSD++GV  TRRFLLEWLSFL+
Sbjct: 502 LIKPWIFTEIKEQRHWDISSSERFDILQDYINLGLLHWGSDSEGVRKTRRFLLEWLSFLH 561

Query: 526 RYVPVGLLERPPQRINERPPTYFGRDDLETLMASSN------------------------ 561
           RY+PVGLLE  PQ+INERPP Y GRDDLETLMAS+N                        
Sbjct: 562 RYIPVGLLETLPQKINERPPYYVGRDDLETLMASANCADWVKIRPQLFVSHDNLENLMAS 621

Query: 562 --CTD-WIKISEMLLGPVPDGFQFLPKHKANSY 591
             C + W+K+ EM LGPVPD FQFL KHKA+SY
Sbjct: 622 ANCAEKWVKLREMFLGPVPDDFQFLAKHKASSY 654


>UniRef50_Q6PEH0 Cluster: Zgc:63779; n=8; Chordata|Rep: Zgc:63779 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 660

 Score =  541 bits (1334), Expect = e-152
 Identities = 253/438 (57%), Positives = 322/438 (73%), Gaps = 10/438 (2%)

Query: 159 NREKFDQWKDDTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGE 218
           + E+ +Q  + +KNT     QTQ   ++ N ++  K  +      +   KN + SA+  E
Sbjct: 227 HEEQREQTDEQSKNTED---QTQTNNQRENANIQSKNTEDQRQSVEDPSKNGSDSANRRE 283

Query: 219 D----IK-IGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTC 273
                IK IG +TD D+IKL P E+K +D+ +KLYL+PLTT GNLPFRR+CK FGAD+TC
Sbjct: 284 TQVPPIKTIGPITDADIIKLRPCEKKQVDFRDKLYLAPLTTCGNLPFRRVCKRFGADITC 343

Query: 274 GEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLN 333
           GEMA+C +LL+G   EWAL+KRH +EDLFG Q+ G  P  +T+ A+LL +N ++DF+D+N
Sbjct: 344 GEMAMCTNLLQGQASEWALLKRHASEDLFGVQLEGCFPDTMTRCAELLNQNIDVDFVDIN 403

Query: 334 IGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPK 393
            GCPIDL+YKKGGG G+M R    E  VR  + +L +P TVK+RTGV Q+  I H ++P+
Sbjct: 404 SGCPIDLVYKKGGGCGLMTRTSKFEQIVRGMNSVLDVPLTVKIRTGVQQNSNIAHKLIPE 463

Query: 394 MSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIA 453
           M  WG SLIT+HGRSRE RYTK +DW+YI TCAQ A P P++GNGDI SYED ++ R+  
Sbjct: 464 MKKWGVSLITLHGRSREQRYTKLADWDYINTCAQLAAPVPLFGNGDILSYEDAMKARETG 523

Query: 454 PTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVEST 513
             V G+M+ RGALIKPW+F EIKE + WDISS +R +IL+ ++++GLEHWGSDTQGVE T
Sbjct: 524 --VSGIMVARGALIKPWLFTEIKESRHWDISSTERLDILRDFTHFGLEHWGSDTQGVEKT 581

Query: 514 RRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLL 573
           R FLLEWLSFL RY+PVGLLER PQRINERPP Y GRD LETLMAS +  DWI+ISEMLL
Sbjct: 582 RNFLLEWLSFLCRYIPVGLLERVPQRINERPPFYMGRDYLETLMASQHVDDWIQISEMLL 641

Query: 574 GPVPDGFQFLPKHKANSY 591
           GPVP  F FLPKHKAN+Y
Sbjct: 642 GPVPKNFSFLPKHKANAY 659



 Score =  120 bits (290), Expect = 8e-26
 Identities = 70/200 (35%), Positives = 105/200 (52%), Gaps = 14/200 (7%)

Query: 7   GVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEI---TEDKNDS 63
           G  AIK +++  K    E  S     +K +E     D    E KK ++E    T ++   
Sbjct: 11  GAAAIKSQFLTSKEKFHEFLSSGRSSQKNEEDP---DGGEPEKKKIRLENEGETAEQEKK 67

Query: 64  KTKKRGQNKSRPKIFKDGKESKP-CPTILDVESSEQLKICQYNN-CKFIHDSKQFLNSKP 121
           K K RGQNKSRP +     E K  C +I+    S    +C Y   C+F+HD  ++L++K 
Sbjct: 68  KIKMRGQNKSRPHVKPHTYEDKRLCTSIIQERDS----VCPYGEKCRFLHDVSEYLSTKA 123

Query: 122 KDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKF--DQWKDDTKNTLQPSLQ 179
            D+GDQCH++   GKCP G+ CRY   H +AD  N+VN E +     +++T N L   LQ
Sbjct: 124 ADLGDQCHLFNTLGKCPYGLTCRYAKAHTSADLKNMVNTELYRASAGRENTTNLLDKELQ 183

Query: 180 TQLQKKKYNFDLAEKLVKHL 199
            +L+KK+  F  A+  +K +
Sbjct: 184 KRLRKKQQRFPGADAFLKSI 203


>UniRef50_A4RQU5 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 608

 Score =  489 bits (1206), Expect = e-137
 Identities = 239/538 (44%), Positives = 336/538 (62%), Gaps = 18/538 (3%)

Query: 69  GQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFLNSKPKDIGDQC 128
           G    R K  +  +  KP    L  + + + K    + CK+ HD   FL +KP D+   C
Sbjct: 60  GAFNKRAKFAEKSRADKPRERGLCNQLTREGKCAFGDACKYSHDVDAFLKTKPPDLPGTC 119

Query: 129 HVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTK------NTLQPSLQTQL 182
                 G CP G+ CRY   H T +G +     +     +  K      N +   +  +L
Sbjct: 120 TFVNKEGGCPYGVRCRYYGTHATGEGRDGATVAESTTTLEPPKTVEKEMNFVDKDVMVRL 179

Query: 183 QKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGEDIKIGAVTDED------LIKLLPR 236
           +KKKY+F  A+ +VK +  R     K+  T A      K   V +E+        K    
Sbjct: 180 RKKKYDFSRADTIVKEV-LRAMETKKDEQTKAGEESAAKRAKVDEENRTDTGAFTKARVE 238

Query: 237 ERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRH 296
           E++TID+ +KLYL+PLTTVGNLPFRR+CK  GAD+TCGEMALC SLL+GL  EWAL++RH
Sbjct: 239 EKRTIDFKDKLYLAPLTTVGNLPFRRVCKTLGADITCGEMALCTSLLQGLPSEWALLRRH 298

Query: 297 ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPA 356
           ++ED+FG QICG  P  +T+  QLL++  ++DFID+N+GCPID + +KG GS M+ +   
Sbjct: 299 KSEDIFGVQICGGYPDSVTRCCQLLEDTIDVDFIDINMGCPIDSVCQKGYGSMMLEKPKK 358

Query: 357 LETSVRCASKLL-SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTK 415
           +ET +R AS  L     T K R       ++ HT  PK++ WGA+ +T+HGR+R  RY  
Sbjct: 359 METVIRAASAALGKCSLTFKTRMAYTDKSRVAHTFAPKVAEWGAAAMTLHGRTRAQRYRS 418

Query: 416 SSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
            +DWEY +   ++++  P+ GNGD++  +DY    +   +V   M+ RGALIKPW+F EI
Sbjct: 419 VADWEYTKLTKESSS-VPLIGNGDVYMQKDYYTHLE-EHSVDTCMLARGALIKPWLFTEI 476

Query: 476 KEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLER 535
           KE++ WDISS++RF+ILK ++++GLEHWGSDT+GVESTR++LLEW+SF YRY P+GLL+ 
Sbjct: 477 KERRDWDISSRERFDILKSFASFGLEHWGSDTRGVESTRKYLLEWMSFTYRYTPIGLLDH 536

Query: 536 P--PQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591
                 + +RPP + GRDDLETLMAS   +DW+KIS MLLGP P+GF F PKHK+N+Y
Sbjct: 537 SYGAAAMTQRPPAFVGRDDLETLMASEASSDWVKISTMLLGPPPEGFAFQPKHKSNAY 594


>UniRef50_UPI00015B6197 Cluster: PREDICTED: similar to CG10463-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG10463-PA - Nasonia vitripennis
          Length = 584

 Score =  483 bits (1192), Expect = e-135
 Identities = 246/494 (49%), Positives = 319/494 (64%), Gaps = 36/494 (7%)

Query: 6   AGVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKNDSKT 65
           +GVC +K EY+++ S    E   N  K K  E + +  D   + +  K +  E+K D   
Sbjct: 23  SGVCLVKPEYIIEDSVRSNENGTN-GKGKDTEKTETDADAAEDGEPPKKKFKENKKD--- 78

Query: 66  KKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFLNSKPKDIG 125
           K RGQNK R   FK  +E   CP I D+   E  K C  NNC FIHD  ++L  KP DIG
Sbjct: 79  KPRGQNKGRSVPFKTQREHNLCPWIADLTVEEVEKKCSNNNCHFIHDRAEYLKIKPDDIG 138

Query: 126 DQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKD---DTKNTLQPSLQTQL 182
            +C+V+++ GKCPRG ACR GS H T DGFNI+++EKF+ +      TKN +   L  +L
Sbjct: 139 TECYVFELTGKCPRGAACRMGSKHTTPDGFNIIDKEKFEAYTKLPPSTKNQISRELSEKL 198

Query: 183 QK------------KKYNF---DLAEKLVKHLDTRNKSV----DKNLNTSADVGEDI--- 220
           +K            KK+N+   +L +K      T+        DK+         D    
Sbjct: 199 KKYKYNFAKAEKIAKKHNWKSNELFDKSKSQNPTKTPETTQIPDKSETPQTPEKSDTLQT 258

Query: 221 -------KIGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTC 273
                  K+G + D D IKL P E+K IDW +K+ L+PLTTVGNLPFRRICKEFGAD+TC
Sbjct: 259 PEKPKEEKVGPILDTDEIKLHPDEKKKIDWKDKIMLAPLTTVGNLPFRRICKEFGADITC 318

Query: 274 GEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLN 333
           GEMAL   LLKG+++EWALVKRHE+EDLFG QI GNNP ++T+  QLL + TE+DF+DLN
Sbjct: 319 GEMALAPRLLKGVREEWALVKRHESEDLFGVQIAGNNPGVLTRCCQLLNDETEVDFVDLN 378

Query: 334 IGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPK 393
           +GCPIDL+YK+GGG GM++RL  LE+ V+ A+++L IPFTVK RTGVY DK I H ++ K
Sbjct: 379 VGCPIDLVYKQGGGCGMLNRLNILESVVKSATEVLDIPFTVKTRTGVYADKPIAHKLMSK 438

Query: 394 MSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIA 453
             +WGAS+I +HGRSRE RYTK +DW+YIE CAQ A+P PVYG GDI S++DY  +RK  
Sbjct: 439 FKDWGASMINIHGRSREQRYTKLADWDYIEKCAQVASPIPVYGTGDILSWDDYQRVRKTY 498

Query: 454 PTVKGVMIGRGALI 467
           PTV+GV I RGALI
Sbjct: 499 PTVQGVSIARGALI 512



 Score =  121 bits (291), Expect = 6e-26
 Identities = 57/84 (67%), Positives = 63/84 (75%), Gaps = 2/84 (2%)

Query: 508 QGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIK 567
           QGV   R  L+        YVPVG+L  PPQR+N RPP Y GRDDLETLMASSNC DWIK
Sbjct: 502 QGVSIARGALIX--XXXXXYVPVGILVEPPQRMNNRPPYYRGRDDLETLMASSNCADWIK 559

Query: 568 ISEMLLGPVPDGFQFLPKHKANSY 591
           +SEMLLG VPDGF FLPKHKAN++
Sbjct: 560 LSEMLLGKVPDGFNFLPKHKANAW 583


>UniRef50_Q9TYN2 Cluster: Putative uncharacterized protein
           Y37E11B.5; n=2; Caenorhabditis|Rep: Putative
           uncharacterized protein Y37E11B.5 - Caenorhabditis
           elegans
          Length = 554

 Score =  455 bits (1121), Expect = e-126
 Identities = 238/535 (44%), Positives = 331/535 (61%), Gaps = 25/535 (4%)

Query: 64  KTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNN-CKFIHDSKQFLNSKPK 122
           K ++RG NK+R K  K  +       +    S  Q   C++   C   HD   FL  KP 
Sbjct: 38  KRERRGMNKTRRKDMKHAETRIRAAAVRLCPSVIQPVACKFGEKCNCEHDISAFLAKKPA 97

Query: 123 DIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTKNTLQPSLQTQL 182
           DIG  C +Y  RG CP   ACR+G  H+   G    + +  ++  + T N     +Q  L
Sbjct: 98  DIGVACPLYDARGACPFSYACRFGGAHLDEAGQQ--SEKSPEKPYEPTTNCHSMKIQVAL 155

Query: 183 QKKKYNFDLAEKLVKHLDTRNKSV-DKNLNTSADVGEDIKIGAVTDEDLIKLLPRERKTI 241
           +K++Y+F+  EK ++ +   N  V + +L+T         +GA+  E      P    ++
Sbjct: 156 RKREYDFEKTEKALEAIKNENFEVLELSLST---------VGAMCREKK----PLNMGSL 202

Query: 242 DWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDL 301
           D   K YL+PLTTVGNLPFRRIC ++GAD+TCGEMAL  S+L G   E++L+KRH  E +
Sbjct: 203 D--GKKYLAPLTTVGNLPFRRICVDYGADITCGEMALATSILSGTASEYSLLKRHPCEKI 260

Query: 302 FGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361
           FG Q+ G     + K +Q++ EN ++DFID+N+GCPID++ +KGGG  +  R   L   +
Sbjct: 261 FGVQLAGGFADTMAKASQIVVENFDVDFIDINMGCPIDVVNQKGGGCALPSRPQKLFEVL 320

Query: 362 RCASKLLS--IPFTVKMRTGVYQD--KKITHTIVPKMSNWGA-SLITVHGRSREARYTKS 416
                +L    P TVK+RTG+ +   K   +    K  +W    LIT H RS+E RYT+ 
Sbjct: 321 AATKSVLGGCCPLTVKIRTGMKEGVLKAPEYVEHMKKHSWHTPDLITFHPRSKEQRYTRL 380

Query: 417 SDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
           ++W++     +A  P P++  GDI S+EDY E  +  P V G+MIGRGALIKPWIF EI 
Sbjct: 381 ANWDFTFPVQEATKPVPLWVCGDILSWEDYYERLEQYP-VNGIMIGRGALIKPWIFTEID 439

Query: 477 EQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERP 536
           E++ WDISS +RF++LKK+ +YGL+HWGSD  GVE TRRFLLE+LSF  RY+PVG+LER 
Sbjct: 440 ERRTWDISSTERFDLLKKFVDYGLDHWGSDDAGVERTRRFLLEFLSFQCRYIPVGILERL 499

Query: 537 PQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591
           PQRIN+RPP + GR++LETL++S    DWI+IS  LLGP P+GFQF+PKHKA+SY
Sbjct: 500 PQRINDRPPRFCGRNELETLLSSQKADDWIEISTRLLGPTPEGFQFIPKHKASSY 554


>UniRef50_Q01ML2 Cluster: H0613H07.1 protein; n=10; Eukaryota|Rep:
           H0613H07.1 protein - Oryza sativa (Rice)
          Length = 685

 Score =  451 bits (1111), Expect = e-125
 Identities = 209/394 (53%), Positives = 277/394 (70%), Gaps = 3/394 (0%)

Query: 199 LDTRNKSVDKNLNTSADVGEDIKIGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNL 258
           L+T  +S D NL+   +   +      TD      L RE+K ID+  KLYL+PLTTVGNL
Sbjct: 288 LNTNTESEDPNLSNGLEPSNNAS-SCRTDLITTPHL-REKKIIDFREKLYLAPLTTVGNL 345

Query: 259 PFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVA 318
           PFRR+CK  GAD+TCGEMA+C +LL+G   EWAL++RH +EDLFG QICG  P  + +  
Sbjct: 346 PFRRLCKTLGADITCGEMAMCTNLLQGQASEWALLRRHSSEDLFGVQICGAYPDTVARTV 405

Query: 319 QLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRT 378
           +L+     +DFID+N+GCPID++  KG GS ++ +   +++ V+ AS +   P TVK+RT
Sbjct: 406 ELVDNECSVDFIDINMGCPIDIVVNKGAGSSLLTKPMRIKSIVQAASTVTEKPLTVKVRT 465

Query: 379 GVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ-AATPCPVYGN 437
             ++ +    +IV  + +WGAS ITVHGRSR+ RY+K +DW+YI  CAQ A     V GN
Sbjct: 466 AFFEGRNRADSIVSDIYDWGASAITVHGRSRQQRYSKLADWDYIYQCAQKAPDQLHVVGN 525

Query: 438 GDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSN 497
           GD+FS+ D+ +       +   MI RGALIKPWIF E+KEQ+ WDI+S +RF ILK +  
Sbjct: 526 GDVFSFTDWNKHVSGCSKISTCMIARGALIKPWIFTEVKEQRHWDITSGERFNILKDFVT 585

Query: 498 YGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLM 557
           +GLEHWGSD++GVE+TR FLLEWLS+  RY+PVGLL+  PQR+N RPP+Y GRDDLETLM
Sbjct: 586 FGLEHWGSDSKGVETTRYFLLEWLSYTCRYIPVGLLDVIPQRLNWRPPSYCGRDDLETLM 645

Query: 558 ASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591
            S +  DWI+ISEMLLG VP+GF F PKHK+N+Y
Sbjct: 646 ISDSAADWIRISEMLLGKVPEGFTFTPKHKSNAY 679



 Score = 54.8 bits (126), Expect = 6e-06
 Identities = 42/157 (26%), Positives = 68/157 (43%), Gaps = 15/157 (9%)

Query: 70  QNKSRPKIFKDGKESKPCPTILDVE--SSEQLKICQY-NNCKFIHDSKQFLNSKPKDIGD 126
           + KS+ ++ ++ K+ +   + L +E   S  +  C+Y ++C+F HD   +L  KP D+  
Sbjct: 71  EKKSKRQLKRERKQEQKSSSHLCIEVGKSGNVSSCKYGDSCRFSHDIDAYLAQKPADLEG 130

Query: 127 QCHVYKVRGKCPRGIACRYGSDH--ITADGFNIVNREKFDQWKDDTKNTLQPSLQTQLQK 184
            C    +   CP G+ CR+   H  I A   N+  + +         N L   +Q  L K
Sbjct: 131 TCPFTNLDQLCPYGLTCRFLGTHKDIHAASGNLSEKHEI--------NALNKDIQKLLWK 182

Query: 185 KKYNFDLAEKLVKHLDTRN--KSVDKNLNTSADVGED 219
            KY F  A   +K L  +   KS     N    V  D
Sbjct: 183 NKYKFPKASAQIKLLGLKEVIKSKPDAANDDKKVNHD 219


>UniRef50_Q582L4 Cluster: TRNA-dihydrouridine synthase 3, putative;
           n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 3,
           putative - Trypanosoma brucei
          Length = 528

 Score =  418 bits (1030), Expect = e-115
 Identities = 208/437 (47%), Positives = 281/437 (64%), Gaps = 10/437 (2%)

Query: 157 IVNREKFDQWKDDTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADV 216
           +V  ++ D  +D  ++   PS + +    K   D  E+    L   N   + ++   + V
Sbjct: 85  VVRGKRKDTKRDRREDCQAPSGEAESTAGKVKHDDEERGTPALQQTNTD-ESHITVKSAV 143

Query: 217 GEDIKIGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEM 276
                  A   E+ ++    + K + ++NKL L+PLTTVGNLPFRR+CKE+GAD+T GEM
Sbjct: 144 AR-----ASNTEESMRERSAQHKAL-FSNKLVLAPLTTVGNLPFRRVCKEYGADITVGEM 197

Query: 277 ALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENT-ELDFIDLNIG 335
           A+  +L +  K EW+L++RH +ED+FG QI  + P+     AQ ++E+    DF+D+N G
Sbjct: 198 AIVHNLNRLQKSEWSLLRRHSSEDIFGLQIAVSRPHDAITWAQAVEESGFSYDFVDINCG 257

Query: 336 CPIDLIYKKGGGSGMMHRLP-ALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKM 394
           CP+D +   G G G+  R    L   V+      S P T+K R G  ++    H  +   
Sbjct: 258 CPVDKVVLSGCGCGLWERKGNRLRDVVQSLVAHQSKPVTIKCRMGPDEENPELHKHIADY 317

Query: 395 SNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAP 454
             WGA+ +T+HGRSR  RYTK ++W YI+ CA + T  PV GNGDIFS ED VE R  + 
Sbjct: 318 ETWGAAAVTIHGRSRRQRYTKLANWSYIDNCA-SLTSLPVIGNGDIFSCEDIVEHRAQSK 376

Query: 455 TVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTR 514
            V   MIGRGAL+KPWIF EIK  ++WDISS +RFE+L+++ N+GL HWG+D +GV +TR
Sbjct: 377 NVSSFMIGRGALVKPWIFEEIKTGRVWDISSHERFEMLRRFCNFGLSHWGADERGVLNTR 436

Query: 515 RFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLG 574
           RFL EWLSFL RYVPVGLLERPPQRINERPP Y GRD+LETLMAS +  DWI+ISEMLLG
Sbjct: 437 RFLCEWLSFLCRYVPVGLLERPPQRINERPPYYEGRDELETLMASDSAVDWIRISEMLLG 496

Query: 575 PVPDGFQFLPKHKANSY 591
           P  D F+F PKHK+N+Y
Sbjct: 497 PAGDKFRFTPKHKSNAY 513


>UniRef50_Q54CU9 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 671

 Score =  415 bits (1023), Expect = e-114
 Identities = 189/391 (48%), Positives = 266/391 (68%), Gaps = 4/391 (1%)

Query: 202 RNKSVDKNLNTSADVGEDIKIGAVTDEDLIK-LLPRERKTIDWNNKLYLSPLTTVGNLPF 260
           + +  +K   T     E  +    T+ D++  L   E+K I++ N+L L+PLTTVGNLPF
Sbjct: 280 KTEKTEKTETTETKKEEFKQSNENTEIDIMTPLKANEKKRINFENQLILAPLTTVGNLPF 339

Query: 261 RRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQL 320
           RRICK  GAD+T GEMAL   LL+G K E AL+KRH  ED FG QICG+      K A+ 
Sbjct: 340 RRICKRLGADITIGEMALTTKLLEGTKSELALLKRHPCEDKFGVQICGSYVDAAVKCAEF 399

Query: 321 LQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGV 380
           ++   + DF+D+N GCPIDL+   G G+ +M R   +E  +R  S  LS P T+K+R G 
Sbjct: 400 IENEIDADFVDINSGCPIDLVCNMGAGAALMERPKKVEQLLRGISSSLSCPTTIKIRIGK 459

Query: 381 YQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDI 440
            +D    H ++P +  WGA  +T+HGRSR  RY++ ++W+Y++ C++ ++  P+ GNGDI
Sbjct: 460 SEDAPTAHKLIPSLGEWGACAVTLHGRSRAQRYSRLANWDYVKQCSEVSS-IPLIGNGDI 518

Query: 441 FSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGL 500
           ++Y+D V +   +  V  +MI RGALIKPWIF EIKE++ WDIS+ +R + ++ ++NYGL
Sbjct: 519 YNYQDVVNIYD-SSKVSSIMIARGALIKPWIFTEIKEKREWDISASERLDFIRDFANYGL 577

Query: 501 EHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASS 560
           +HWGSD  GV++TR+FLL WLSF +RY+PVGLL++    +NERPP YFGR DLETL+AS+
Sbjct: 578 DHWGSDRIGVDNTRKFLLNWLSFSHRYIPVGLLDK-VHYMNERPPAYFGRSDLETLLAST 636

Query: 561 NCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591
              DWIKI+EM LGPV   + F+PKH +NSY
Sbjct: 637 QVKDWIKITEMFLGPVTSDYSFVPKHNSNSY 667



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 59/179 (32%), Positives = 87/179 (48%), Gaps = 27/179 (15%)

Query: 47  LEFKKT-KIEITEDKNDSKTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYN 105
           L FKK  K+E+  DK   K + R Q        ++    K CP I     S+ L +C++N
Sbjct: 73  LPFKKIEKVEV--DKAAKKKEFRNQ-------LRESMNDKLCPKI-----SKGL-VCEFN 117

Query: 106 N-CKFIHDSKQFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFD 164
             CKF HD +++L SKPK IG  C  ++  G+C  G+ C +G  HI  D   IVN+E   
Sbjct: 118 ETCKFSHDVEKYLASKPKSIG-ICQNFQTYGECKYGLNCYFGECHI-VDNKTIVNKELIG 175

Query: 165 QWKD-DTKNTLQPSLQTQLQKKKYNFDLAEKL-------VKHLDTRNKSVDKNLNTSAD 215
           + +   T N +   +Q QL+   Y F  +E         V+ +  RN + +KN N   D
Sbjct: 176 KVEPVKTLNEVSNEIQIQLKTNNYPFPKSEIYFNENGISVRQIKGRNNNNNKNNNKQND 234


>UniRef50_Q010A0 Cluster: tRNA-dihydrouridine synthase; n=1;
           Ostreococcus tauri|Rep: tRNA-dihydrouridine synthase -
           Ostreococcus tauri
          Length = 639

 Score =  410 bits (1009), Expect = e-113
 Identities = 209/505 (41%), Positives = 312/505 (61%), Gaps = 26/505 (5%)

Query: 98  QLKICQYNN-CKFIHDSKQFLNSKPKDIGDQCHVY--KVRGKCPRGIACRYGSDHITADG 154
           Q ++C+    C + HD   +  SKP D+     V+       CP G+ CR+ S H     
Sbjct: 131 QGEVCRLGKRCGYSHDLSAYRASKPSDVERAACVFINAESDSCPFGVRCRFESSH----- 185

Query: 155 FNIVNREKFDQWKDDTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSA 214
                + K D+  +   N L  ++Q +L + +Y F  ++K ++     N  V K L+ + 
Sbjct: 186 ----RKMKSDKTVEMPMNILDDAMQKRLSRNEYPFPRSDKALRE---GNLEV-KCLSFAQ 237

Query: 215 DVGEDIKIGAVTDEDLIKLLPRERK-TIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTC 273
               D + G +   +  ++  RE++ ++++  K+Y++PLTTVGNLPFRRIC + GAD+T 
Sbjct: 238 KHKLDRREGFLGSFEPGRVNAREKRVSLEFKGKIYVAPLTTVGNLPFRRICTDLGADITV 297

Query: 274 GEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLN 333
            EMA+  +LLKG ++EWALV+RH  E  FG QICG  P ++T+ A+LL      DFID+N
Sbjct: 298 SEMAMASNLLKGDRKEWALVRRHPIEKCFGIQICGGYPDLMTRCAELLDNEVHCDFIDVN 357

Query: 334 IGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQD--KKITHTIV 391
           +GCPID +  KG G  +M     L+  VR  + + S P T+K+R G + D  + + H I+
Sbjct: 358 MGCPIDGVCAKGAGGSLMRDTDRLKRVVRSMTSVSSTPVTIKLRMGYFDDPSRYVAHDII 417

Query: 392 PKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA--TPCPVYGNGDIFSYEDYVEM 449
            K  +WGA   T+HGR+RE RY++ +DW YI  CA A+     P+ GNGD+++Y+D+ E 
Sbjct: 418 SKAKSWGAYAATLHGRTREQRYSRLADWSYIHRCADASALNNLPLIGNGDVYTYQDWNE- 476

Query: 450 RKIA-PTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQ 508
            +IA   +   MIGRGA+IKPW+  EIKEQ+ WDIS+ +R ++ K + +YGLEHWGSD+ 
Sbjct: 477 -QIANEKISTCMIGRGAIIKPWLMTEIKEQRHWDISANERLDLFKDFVHYGLEHWGSDSV 535

Query: 509 GVESTRRFLLEWLSFLYRYVPVGLLER-PPQRINERPPTYFGRDDLETLMASSNCTDWIK 567
           GVE TRR+LLEW+S+ +RYVP+GLLE+    +++ RP  Y GR DLET +AS    DW++
Sbjct: 536 GVEKTRRYLLEWMSYTHRYVPIGLLEQNVVPKLHLRPMRYVGRSDLETKLASDKLEDWLE 595

Query: 568 ISEML-LGPVPDGFQFLPKHKANSY 591
           +SE+  LG     F+F+PKH +NSY
Sbjct: 596 LSELSGLGKPDPSFRFVPKHASNSY 620


>UniRef50_Q5KC68 Cluster: TRNA dihydrouridine synthase, putative;
           n=2; Filobasidiella neoformans|Rep: TRNA dihydrouridine
           synthase, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 725

 Score =  407 bits (1003), Expect = e-112
 Identities = 190/376 (50%), Positives = 259/376 (68%), Gaps = 16/376 (4%)

Query: 231 IKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEW 290
           + L P E++ ++W    YL+PLTTVGNLPFRR+C ++GA +T  EMAL + L+ G K+EW
Sbjct: 344 VPLRPEEKRRLNWEGGRYLAPLTTVGNLPFRRLCVDYGATITVSEMALAQPLVYGAKEEW 403

Query: 291 ALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTE----LDFIDLNIGCPIDLIYKKGG 346
           ALV+RHE+E +FG Q+ G  P  +   A+++         +DF+D+N+GCPIDL++ +G 
Sbjct: 404 ALVRRHESEKMFGVQVAGGFPNRMVPAAEVIANTIGKGGGVDFVDVNMGCPIDLVFNQGA 463

Query: 347 GSGMMHRLPALETSVRCASKLLS-IPFTVKMRTGVYQDKKITHTIVPK-MSNWGASLITV 404
           GS +M     L   +   ++ L  IP TVK RTGV   K   H ++P+ ++ WGA  +T+
Sbjct: 464 GSALMDSPGRLGKLLVGMNRALGDIPLTVKFRTGVAHGKPNAHKLIPRFVTEWGAGALTI 523

Query: 405 HGRSREARYTKSSDWEYIETCAQAAT---------PCPVYGNGDIFSYEDYVEMRKIAPT 455
           HGRSR+ RY+K +DWEYI+TC  A           P P++GNGD FS   Y E    +  
Sbjct: 524 HGRSRQQRYSKPADWEYIKTCVTALRESVADANLPPVPIFGNGDCFSAASYYEEMDRSG- 582

Query: 456 VKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRR 515
           V GVM+ RGALIKPWIF EIKE++ WDIS+ +R E +KK++ +GL HWGSDTQGV +TRR
Sbjct: 583 VDGVMVARGALIKPWIFTEIKERREWDISAVERLEGIKKFAEFGLSHWGSDTQGVNTTRR 642

Query: 516 FLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGP 575
           FL E LSF +RY+P+GLLER P ++NERPP Y GR++LETL+AS    DW+KISEM LG 
Sbjct: 643 FLCEALSFQHRYIPIGLLERLPAKLNERPPAYRGRNELETLLASPFAGDWVKISEMFLGK 702

Query: 576 VPDGFQFLPKHKANSY 591
           V +GF F+PKHK+N+Y
Sbjct: 703 VDEGFSFVPKHKSNAY 718


>UniRef50_Q4QEF9 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 595

 Score =  404 bits (994), Expect = e-111
 Identities = 193/368 (52%), Positives = 256/368 (69%), Gaps = 3/368 (0%)

Query: 226 TDEDLIKLLPRERKTID-WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK 284
           T+E L +++ R+  +   +  KL L+PLTTVGNLPFRRICK FGADVT  EMA+  +L +
Sbjct: 215 TEESLREVIARQSSSRGLFAEKLVLAPLTTVGNLPFRRICKSFGADVTLSEMAVVFNLNR 274

Query: 285 GLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENT-ELDFIDLNIGCPIDLIYK 343
             K EW+L++RHE+ED+FG Q+  + P      AQ L+ +    DF+D+N GCP++ I K
Sbjct: 275 LQKSEWSLLRRHESEDIFGIQLAVSRPQEAATFAQALEASGFSYDFLDINCGCPVEKIVK 334

Query: 344 KGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLIT 403
            G G G+  R   L   V   +   S P  +K R G+ +D    H  + + S WGA+ +T
Sbjct: 335 SGCGCGLWQRTERLRDVVESLAIYQSRPVAIKCRIGLDEDIPTLHQQIHRYSAWGAAAVT 394

Query: 404 VHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGR 463
           VHGRSR+ RYTK ++W+Y++ CAQ  T  PV GNGDI S ED +E R+  P +   MIGR
Sbjct: 395 VHGRSRKQRYTKFANWDYVDQCAQL-TSLPVIGNGDIMSLEDVLEHRERQPHIASHMIGR 453

Query: 464 GALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSF 523
           GALIKPW+F EIK  ++ DISS +R ++LKK+  +G+ HWG+D +GV +TRRFL EWLSF
Sbjct: 454 GALIKPWLFEEIKTGQVKDISSSERLDMLKKFCAHGMAHWGADERGVMTTRRFLCEWLSF 513

Query: 524 LYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFL 583
           L+RYVPVGLLER PQRINERPP Y GRD+LETLM+S +  DW++ISE+LLGPV   F+F 
Sbjct: 514 LHRYVPVGLLERLPQRINERPPFYEGRDELETLMSSDSVKDWVRISELLLGPVERQFRFT 573

Query: 584 PKHKANSY 591
           PKHK+NSY
Sbjct: 574 PKHKSNSY 581


>UniRef50_A3LUK5 Cluster: Dihydrouridine synthase of tRNA; n=6;
           Saccharomycetales|Rep: Dihydrouridine synthase of tRNA -
           Pichia stipitis (Yeast)
          Length = 613

 Score =  399 bits (982), Expect = e-109
 Identities = 233/613 (38%), Positives = 357/613 (58%), Gaps = 56/613 (9%)

Query: 7   GVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKNDSKTK 66
           G+ AIK E+++QK  I++                SFDD+  E  +  +E  +     K K
Sbjct: 25  GMAAIKPEFIVQKDRIVD----------------SFDDDEAEGGERGVEEGKSGKGGKKK 68

Query: 67  KRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYN--NCKFIHDSKQFLNSKPKDI 124
           +RGQNK+R  + +  +E + C ++LD ++   +K C Y    C+  H+ +++L SKP DI
Sbjct: 69  RRGQNKNRD-LKQKREEIRLCTSLLDPDN---IKTCAYGPEQCRSTHNVEEYLASKPVDI 124

Query: 125 GDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVN---REKFDQWKDDTK-NTLQPSLQT 180
              C V++  G CP G+ CR+   H   +   ++    R +  + + + + N +    + 
Sbjct: 125 EGICPVFRAIGYCPAGLKCRWLQSHYDKETRKLIKDLGRTEASKIELNYEVNNVSHEARG 184

Query: 181 QLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGEDIKIGAVTDEDLIKLLPRERKT 240
           +L+KK+Y+F +A K+++++D+  ++ D+N+   A+  E  K    T  D    +  E+K 
Sbjct: 185 KLRKKQYDFAIAGKVIEYIDSTVQN-DENI---ANAKEQRKNNEATYVDAPYKIA-EKKR 239

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE- 299
           +D+ N   +SPLTTVGNLP+RR+ K+ GAD+T  EMAL   LL+    EWAL K H TE 
Sbjct: 240 LDFRNAKIVSPLTTVGNLPYRRLMKKLGADITYSEMALSVPLLQATNAEWALPKAHRTEY 299

Query: 300 DLFGAQICGNNPYIITKVAQLLQENTE-LDFIDLNIGCPIDLIYKKGGGSGMMHRLPALE 358
             +G QI  +  +   KVA+++   TE +  ++LN GCPIDL+Y++G GS ++ + PA  
Sbjct: 300 PGYGVQIATSKHWAAAKVAEIISRETEHVSELNLNCGCPIDLLYRQGQGSALLEQ-PARL 358

Query: 359 TSVRCASKLLS--IPFTVKMRTGVYQDKKITHTIVPK-MSNWGASLITVHGRSREARYTK 415
             +  A    S  IP TVK+RTG  ++K    T+V + ++    + IT+HGRSR+ RYTK
Sbjct: 359 VRILKAMNASSGDIPVTVKIRTGSKENKNTAKTLVERLLAENDVAAITLHGRSRQQRYTK 418

Query: 416 SSDWEYIETCAQAA-----------------TPCPVYGNGDIFSYEDYVEMRKIAPTVKG 458
            +DW YI    Q                     C V GNGD+FS+ D+         +  
Sbjct: 419 EADWNYIAEVGQVVQQWNDKKEENKDSRDTQRTCFV-GNGDVFSHVDWYNAVN-TDGIDS 476

Query: 459 VMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLL 518
           VM+ RGALIKPWIF E++ Q+  D ++ +R +ILK +S+Y LEHWG+D  GV   RRF+ 
Sbjct: 477 VMVARGALIKPWIFEEVEAQQYLDKTATERLDILKTFSDYALEHWGTDEYGVGLARRFMC 536

Query: 519 EWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPD 578
           E+LSF +RY+P+G+LER P +INERPP + GR+++ETL+ S++  DWIKI+EM LG   D
Sbjct: 537 EFLSFTHRYIPLGILERLPPKINERPPQWKGRNEMETLLGSTDYKDWIKITEMFLGKSGD 596

Query: 579 GFQFLPKHKANSY 591
            F F PKHK+NSY
Sbjct: 597 DFVFTPKHKSNSY 609


>UniRef50_Q6C4K3 Cluster: Similar to DEHA0D12364g Debaryomyces
           hansenii; n=1; Yarrowia lipolytica|Rep: Similar to
           DEHA0D12364g Debaryomyces hansenii - Yarrowia lipolytica
           (Candida lipolytica)
          Length = 622

 Score =  392 bits (966), Expect = e-107
 Identities = 222/560 (39%), Positives = 320/560 (57%), Gaps = 37/560 (6%)

Query: 59  DKNDSKTKKRGQNKSRPKIFKDGKES-KPCPTILDVESSEQLKICQYNN-CKFIHDSKQF 116
           +K + K KK GQNK+R    K  K++ K C + L  +     + C Y + CKF HD +++
Sbjct: 68  EKPEEK-KKGGQNKNRS--LKQRKDAIKMCSSALQFKEDGSPQECSYGDKCKFEHDLQKY 124

Query: 117 LNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTKNTLQP 176
           L SKPKDI   C V+ + G+CP+G  CR+ S H  ++G  +V+ EK     D+ +     
Sbjct: 125 LESKPKDIEGVCPVFDLTGQCPQGYKCRWLSSHRDSEGKLLVDEEKKKANADNKELNHVF 184

Query: 177 SLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGEDIKIGAVTDEDLIKLLPR 236
                LQ+KKY+   +++ +K +D +    + +  T  +  E I+I      D  ++ P 
Sbjct: 185 KHLNPLQRKKYDLSKSDEAIKLIDAQIVRDEDDEQTKLEKKETIEI------DTGRIRPS 238

Query: 237 ERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRH 296
           E+K +D   K  +SPLTTVGNLP+RR+ K+ GADVT GEMAL   L++G K EWAL + H
Sbjct: 239 EKKKLDLKGKYIVSPLTTVGNLPYRRLMKDLGADVTYGEMALTLPLIQGHKAEWALTRCH 298

Query: 297 ETE----DLFGAQICGNNPYIITKVAQLLQE-NTELDFIDLNIGCPIDLIYKKGGGSGMM 351
            +E    + FG Q+     +   K AQ + E  T +  I+LN GCPIDL+Y++G GS +M
Sbjct: 299 SSEVTEGNHFGVQVTAPKHWQAIKAAQAVSELCTGISEINLNCGCPIDLVYRQGAGSALM 358

Query: 352 HRLPALETSVRCASKLL-SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSRE 410
            +       VR  S +   +P TVKMRTG              ++    +  T+HGRSR 
Sbjct: 359 DQQGKTARIVRGMSMVSGDVPITVKMRTGTGSTPTAKKLTARLLAEGQTAAFTLHGRSRA 418

Query: 411 ARYTKSSDWEYIETCAQAAT-------------------PCPVYGNGDIFSYEDYVEMRK 451
            RYTK +DW YI   A +                     P  V GNGD +++ D+     
Sbjct: 419 QRYTKLADWNYIREVADSVVNTRDDVREKSELDDHVISHPTWVVGNGDCYTWSDWHRAVD 478

Query: 452 IAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVE 511
            A  V  VM+ RGALIKPWIF E++ ++  D S+ +R E  +K++ YGLEHWGSD  GV 
Sbjct: 479 EA-HVDSVMVARGALIKPWIFEEVESRQHIDKSATERLEYFQKFAQYGLEHWGSDQYGVN 537

Query: 512 STRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEM 571
            TRR+L E++SF +RYVP G+LE  P ++N+RP  + GRD++ETL+ SS+  DWIK++E 
Sbjct: 538 QTRRYLCEFMSFTHRYVPSGILEYLPAKMNDRPDLWKGRDEMETLLGSSDYRDWIKVTER 597

Query: 572 LLGPVPDGFQFLPKHKANSY 591
            LGPV D F+F PKHK+N+Y
Sbjct: 598 FLGPVGDEFEFTPKHKSNAY 617


>UniRef50_A4S3Q5 Cluster: Predicted protein; n=2; Eukaryota|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 361

 Score =  386 bits (949), Expect = e-105
 Identities = 174/360 (48%), Positives = 245/360 (68%), Gaps = 7/360 (1%)

Query: 238 RKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHE 297
           RK +D+  KLY++PLTTVGNLPFRR+C + GAD+T  EMA+  +LLKG ++EWAL++RH 
Sbjct: 1   RKELDFKGKLYVAPLTTVGNLPFRRVCTDLGADITVSEMAMASNLLKGDRKEWALLRRHP 60

Query: 298 TEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPAL 357
           +E  +G Q+CG  P ++ + A+L+      DFID+N+GCPID +  KG GS +M     L
Sbjct: 61  SEKCYGIQVCGGYPDLMARCAELIDNEVSCDFIDVNMGCPIDGVCAKGAGSSLMRDTDRL 120

Query: 358 ETSVRCASKLLSIPFTVKMRTGVYQD--KKITHTIVPKMSNWGASLITVHGRSREARYTK 415
           +  VR  + + S P T+K+R G + D  K + H I+P+   WGA   T+HGR+RE RY++
Sbjct: 121 KNVVRTMAAVSSTPVTIKLRMGYFDDPSKYVAHDIIPRAKAWGAFAATLHGRTREQRYSR 180

Query: 416 SSDWEYIETCAQAA--TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473
            +DW YI  CA  A  +   + GNGD+++YEDY   +     V   MIGRGA+IKPW+  
Sbjct: 181 LADWSYIHRCADVAAKSEFTLIGNGDVYTYEDY-NAQVADNKVATCMIGRGAIIKPWLMT 239

Query: 474 EIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLL 533
           EIKEQ+ WDIS+ +R ++ K +  YGLEHWGSD+ GVE TRR+LLEW+S+ +RYVP+GLL
Sbjct: 240 EIKEQRHWDISANERLDLFKDFCQYGLEHWGSDSMGVEKTRRYLLEWMSYTHRYVPIGLL 299

Query: 534 ER-PPQRINERPPTYFGRDDLETLMASSNCTDWIKISEML-LGPVPDGFQFLPKHKANSY 591
           E+    +++ RP  Y GR DLET +AS    DW+++SE+  LG     F+F+PKH +NSY
Sbjct: 300 EQNVVPKLHLRPMRYVGRSDLETKLASDRLEDWLELSEICGLGKPDASFKFVPKHASNSY 359


>UniRef50_Q5CRK5 Cluster: Ylr401cp-like protein with 2 CCCH domains
           plus Dus1p tRNA dihydrouridine synthase Tim barrel; n=2;
           Cryptosporidium|Rep: Ylr401cp-like protein with 2 CCCH
           domains plus Dus1p tRNA dihydrouridine synthase Tim
           barrel - Cryptosporidium parvum Iowa II
          Length = 707

 Score =  342 bits (840), Expect = 2e-92
 Identities = 187/441 (42%), Positives = 260/441 (58%), Gaps = 51/441 (11%)

Query: 199 LDTRNKSVDKNLNTSADVGEDIKIGAVTDEDLIKLLPRERKTID---WNNKLYLSPLTTV 255
           LD +       +N   ++    ++   T++ LI +   E++      + NKL L+PLTTV
Sbjct: 267 LDEKGPKTITEINNQPNIEIQQELKLSTEDMLIGISIHEKEKCKHKIFRNKLILAPLTTV 326

Query: 256 GNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIIT 315
           GNLPFRR+C +FGADVT  EM LC  +L G   E AL+K+   E  FG Q+ G N   I 
Sbjct: 327 GNLPFRRLCLKFGADVTVSEMVLCNEILSGKASELALLKKSPEEKYFGIQLAGGNKSTII 386

Query: 316 KVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPF-TV 374
           K  + + E+ E DFID+N  CP+  ++ KG GS ++ R+  LET V+   K++     TV
Sbjct: 387 KTGEFINEHCEFDFIDINAACPLKSLHDKGAGSILVDRVSELETMVKGLKKVMDGKLVTV 446

Query: 375 KMRTG------------------------VYQDKKITHTIVPKMSNWGASLITVHGRSRE 410
           K+R                          +Y + K TH I+  + + G   +T+HGR+  
Sbjct: 447 KVRMSHGGSPINKNLSEKDYFENFENWPVIYHNMK-THKILNILCDSGIDALTIHGRTSF 505

Query: 411 ARYTKSSDWEYIETCAQAATP------------------CP-VYGNGDIFSYEDYVEMRK 451
            RYTK +DW YI+ C+   +                   CP + G GDI +++DY +  +
Sbjct: 506 QRYTKEADWSYIKYCSVLNSKLYSNKVVNNIQNSNHSLICPSIIGCGDIINFQDYQQHIQ 565

Query: 452 IAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVE 511
               V  VMIGRGAL+KPWIF EIKE + WDIS+ +RF+I+K+Y N GLEHWG+D +G+ 
Sbjct: 566 -NDLVDSVMIGRGALLKPWIFTEIKENRNWDISASERFDIIKQYVNLGLEHWGTDKRGIA 624

Query: 512 STRRFLLEWLSFLYRYVPVGLLERP--PQRINERPPTYFGRDDLETLMASSNCTDWIKIS 569
            TRRFLLE+LSF +RY+P+G+LE+P   Q  N R P Y GR+DLET++ASSN +DWIKIS
Sbjct: 625 LTRRFLLEFLSFFHRYIPIGILEQPIHTQNFNWRTPKYIGRNDLETMLASSNSSDWIKIS 684

Query: 570 EMLLGPVPDGFQFLPKHKANS 590
           EM+LG VP  F F+PKHKANS
Sbjct: 685 EMILGKVPSDFVFIPKHKANS 705


>UniRef50_UPI0000499494 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 515

 Score =  332 bits (815), Expect = 2e-89
 Identities = 161/357 (45%), Positives = 228/357 (63%), Gaps = 12/357 (3%)

Query: 237 ERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRH 296
           E+K +D   KL L  L T GNLPFR++ K FG DVT  EM + ESL++G   EWALVKR 
Sbjct: 162 EKKILDLKGKLILPSLCTFGNLPFRKVVKRFGCDVTMTEMIMAESLVEGKTSEWALVKRD 221

Query: 297 ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPA 356
            +ED+FG Q+C  N  +  K  Q+L  + + DF +LN  CPID +YKKG G+ ++ R   
Sbjct: 222 SSEDIFGIQLCVGNSMLAAKACQVLN-SVDCDFYELNCACPIDYVYKKGMGAQLIERPKR 280

Query: 357 LETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS 416
           +E+ +     +   P  +K+RTG      I   ++P  +++GA+++++HGR+R+ RYTKS
Sbjct: 281 IESLLHAMRSVTERPVAIKVRTGK-SSNTIQDVLLPNCADYGAAMVSIHGRTRDQRYTKS 339

Query: 417 SDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
           +DW++I+  A   T CPV G GDI+ Y+DY   + +   V  V IGRGALIKPWI+ EIK
Sbjct: 340 ADWDFIKQ-ATTITQCPVIGVGDIYGYKDY--QKALDCGVATVAIGRGALIKPWIYTEIK 396

Query: 477 EQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERP 536
           E++ WDISS +R +IL++Y+  GL HWGSD QG+  TR F+   L+F+ RYVPV  +   
Sbjct: 397 EKRDWDISSSERLDILRQYALDGLSHWGSDAQGISKTREFMCHHLTFMTRYVPVHCVIET 456

Query: 537 PQRI-----NERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKA 588
            Q I     N+R   Y  RDD+E L+ S    D+IKI+EM LGP P  F ++PKH++
Sbjct: 457 NQEISIKVRNDRVMCY--RDDMEKLLTSDRLEDYIKITEMFLGPAPKDFVYVPKHQS 511



 Score = 60.9 bits (141), Expect = 9e-08
 Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 7/117 (5%)

Query: 102 CQYNNCKFIHDSKQFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNRE 161
           C+  NCK+ HD K++L+ +   +   C ++K  G CP G  C +   HI   G  I N E
Sbjct: 64  CERENCKYSHDLKEYLSKRTDLLEGICPLFKEYGFCPNGYTCEWYKSHINEQGELITNNE 123

Query: 162 --KFDQWKDDTKNTLQPSLQTQLQKKKYNFDLAEKL----VKHLDTRNKSVDKNLNT 212
             K   +K+   NT +P     L+  K++F + E+      K LD + K +  +L T
Sbjct: 124 LMKLHPFKEPL-NTQKPETLHVLRTNKFDFKIPEEFPVPEKKILDLKGKLILPSLCT 179


>UniRef50_Q9UTH9 Cluster: tRNA dihydrouridine synthase Dus3; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus3 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 617

 Score =  324 bits (796), Expect = 4e-87
 Identities = 173/427 (40%), Positives = 254/427 (59%), Gaps = 32/427 (7%)

Query: 194 KLVKHLDTRNKSVDKNLNTSADVG-EDIKIGAVTDEDLIKLLPRERKTIDWNNKLYLSPL 252
           K  + +      V KN   S +V  ++I   A ++  L  L P+E+  IDW ++  L+PL
Sbjct: 187 KETESVSLEETGVLKNQTVSVNVDLKEISSQARSNIALPTLRPQEKNLIDWRDRKILAPL 246

Query: 253 TTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVK--RHETE-------DLFG 303
           TTVGN PFRR+C   GAD    EMA+C  L++G + EWALV+   +E E        + G
Sbjct: 247 TTVGNPPFRRLCGSLGADTFYSEMAMCYPLMQGHQPEWALVRGLNYEREMMRGGRRGILG 306

Query: 304 AQICGNNPYIITKVAQLLQENTE-LDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
            Q+     +  TK AQ++ E  + +DF+DLN GCPIDL++++G GS ++     L  +++
Sbjct: 307 VQLATGKLWQATKTAQVIAEQCDGVDFLDLNCGCPIDLVFRQGAGSSLLENPGRLLRNLQ 366

Query: 363 CASKLLS-IPFTVKMRTGVYQDKKITHTIVPKMSN-WGASLITVHGRSREARYTKSSDWE 420
               +   IP TVK+R G   D  +   ++ ++ N    S  T+HGRSR+ RY+K+++W+
Sbjct: 367 GMDAVSGQIPVTVKLRMGNKDDHPVVKNLIGRIFNETNTSAATLHGRSRQQRYSKNANWD 426

Query: 421 YIETCAQAAT-----------------PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGR 463
           YI   A                     P  + GNGD +S++D+ +   +   V  VMI R
Sbjct: 427 YIGEIASKVKSMNERIDELPEDSLRTQPLSLIGNGDCYSWQDWYD--GVNKGVDTVMIAR 484

Query: 464 GALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSF 523
           GAL+KPWIF EI+ ++  D SS  R E+L++Y N GLE+WGSD+QGV +TRRF LE++SF
Sbjct: 485 GALVKPWIFEEIEARQFIDKSSTQRLEMLEQYCNNGLEYWGSDSQGVNTTRRFFLEFMSF 544

Query: 524 LYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFL 583
            +RY P+ L E    R+N+RPP Y  RD++ETL+AS+  TDW+K+SE  LGP P+ F F 
Sbjct: 545 FHRYTPIALYEVQRPRLNDRPPLYTARDEMETLLASNKVTDWVKLSEFFLGPTPERFTFT 604

Query: 584 PKHKANS 590
           PKHK+NS
Sbjct: 605 PKHKSNS 611



 Score = 77.8 bits (183), Expect = 8e-13
 Identities = 50/145 (34%), Positives = 78/145 (53%), Gaps = 11/145 (7%)

Query: 56  ITEDKNDS-KTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYN-NCKFIHDS 113
           + +D N   K K+RGQNK R KI    + +  CP I  + +      C Y  NCKF HD 
Sbjct: 17  VKQDGNKKRKRKERGQNKRREKIHVK-ENNALCPAI-SIGNE-----CPYKENCKFPHDV 69

Query: 114 KQFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDH--ITADGFNIVNREKFDQWKDDTK 171
           + +L +K  DIGD+C +++  G CP G  CR+ + H  I ADG   + ++   Q+   T 
Sbjct: 70  EAYLATKAPDIGDKCPIFERYGVCPAGFKCRWLAGHVVINADGKYELIKKPDGQFTLFTV 129

Query: 172 NTLQPSLQTQLQKKKYNFDLAEKLV 196
           NT+   +Q +L+ K+ +   AE ++
Sbjct: 130 NTVGKEVQRKLRTKQLDLSKAESII 154


>UniRef50_Q2UL89 Cluster: Uncharacterized conserved protein; n=15;
           Pezizomycotina|Rep: Uncharacterized conserved protein -
           Aspergillus oryzae
          Length = 730

 Score =  308 bits (755), Expect = 4e-82
 Identities = 226/624 (36%), Positives = 318/624 (50%), Gaps = 102/624 (16%)

Query: 64  KTKKRGQNKSRPKIFKDGKESKP-CPT-ILDVESSEQLKICQYNN-CKFIHDSKQFLNS- 119
           K K  GQN +R   F   ++ K  CP+ I   E S     CQ+   C+F HD + +L   
Sbjct: 107 KKKPTGQNTNRT--FGSSQDEKGLCPSRIFTPEFSPGA--CQWGEKCRFEHDLRTYLKEY 162

Query: 120 KPKDI---GDQCHVYKVRGKCPRGIACRYGSDHIT----ADGFNIV------NREKFDQ- 165
           K  D+      C V+  +GKC  G  CR    H+T    ADG   +       R+K  Q 
Sbjct: 163 KRGDLTTFDGVCPVWDAKGKCLSGWKCRLVGSHMTERETADGRKELVLVEDEERKKKAQP 222

Query: 166 -----WKDDTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGEDI 220
                 +D T N      +  L +KK     A+     LD  ++ ++K ++ + +V E+ 
Sbjct: 223 LVPFAVEDGTANIAPIEAKIALNRKKVKTPRADAYGSWLDKTSRELEKVIH-NREVHEER 281

Query: 221 KIGAVTDEDLIK------------LLPRERKTIDWNNKL-YLSPLTTVGNLPFRRICKEF 267
              + TD+   +             LP E++ I +  +   L+PLTT GNLPFRR+C E 
Sbjct: 282 GAESKTDQAEREKEDNRAQYLEPPFLPSEKRRIYFGPETPVLAPLTTQGNLPFRRLCIEL 341

Query: 268 GADVTCGEMALCESLLKGLKQEWALVKRHETEDL---------------------FGAQI 306
           GA  T  EMAL   L++G + EWAL++ HETE L                     FGAQI
Sbjct: 342 GAQFTYSEMALSMPLIQGQRGEWALMRAHETEMLPPTISPGADVVQGYDHSKDFRFGAQI 401

Query: 307 CGNNPYIITKVAQLLQENT-ELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
             N  +   K  ++L   T  L  IDLN GCPIDL++++G GS ++     LE  +R  +
Sbjct: 402 AANKHWQALKATEVLSAYTPNLRVIDLNCGCPIDLLFREGAGSALLEHPSKLERILRGMN 461

Query: 366 KLLS-IPFTVKMRTGVYQDK----KITHTIVPK--------MSNWGASLITVHGRSREAR 412
            +   IP T K+R G   +     K+   ++          +   G + +T+HGRSR+ R
Sbjct: 462 AVSQEIPITAKIRMGTRDNSPNALKLAERLILGGYESSTLGLGAPGVAALTLHGRSRQQR 521

Query: 413 YTKSSDWEYIETCAQ---------------AATPCP----------VYGNGDIFSYEDYV 447
           YT+ +DW YI  CA                   P P            GNGD +S+ DY 
Sbjct: 522 YTRQADWGYISECAALIKRLNEKTDQVTDTVREPDPRTQPNGGKTWFLGNGDCYSHLDYD 581

Query: 448 EMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDT 507
           +    A  V  VM+GRGALIKPW+F EI+  +  D S+ +R  +++K++ YGLE WGSD 
Sbjct: 582 DHVNNAG-VDTVMVGRGALIKPWLFEEIQAGQYLDKSASERLSLVEKFAKYGLETWGSDE 640

Query: 508 QGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIK 567
            GV +TRRFLLEWLSF  RY+P+GLLE  P RI +RPP++ GR++LETLM S N  DWIK
Sbjct: 641 HGVGTTRRFLLEWLSFACRYIPIGLLEYLPPRIQDRPPSWRGRNELETLMGSHNYKDWIK 700

Query: 568 ISEMLLGPVPDGFQFLPKHKANSY 591
           I+EM LGP    F+F PKHK+N++
Sbjct: 701 ITEMFLGPAHKDFRFEPKHKSNAW 724


>UniRef50_Q06053 Cluster: tRNA-dihydrouridine synthase 3; n=6;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 3 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 609

 Score =  245 bits (600), Expect = 2e-63
 Identities = 139/398 (34%), Positives = 221/398 (55%), Gaps = 40/398 (10%)

Query: 161 EKFDQWKDDTKNTLQPS--LQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGE 218
           E  D ++ + +++++P   +++  Q KK + D+ + +   ++ RNK + ++     +V  
Sbjct: 215 EIIDSFQQECRDSMKPEEEVESTPQLKKQDPDVEQPVAPQVEQRNKELSEHRMKQREVYL 274

Query: 219 DIKIGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMAL 278
             K          +   +E+K +D  +K  +SPLTTVGNLP+RR+ ++ GADVT  EMAL
Sbjct: 275 KYKD--------TRYFAQEKKPLDLYHKKIVSPLTTVGNLPYRRLMRKLGADVTYSEMAL 326

Query: 279 CESLLKGLKQEWALVKRHETE-DLFGAQICGNNPYIITKVAQLLQEN-TELDFIDLNIGC 336
              L++G   EWAL K H +E   FG Q+  +  +   K A+ L  + +E+  I+LN GC
Sbjct: 327 AVPLIQGTNSEWALPKAHTSEFPGFGVQVACSKAWQAAKAAEALANSVSEISEINLNSGC 386

Query: 337 PIDLIYKKGGGSGMMHRLPALETSVRCASKL----LSIPFTVKMRTGVYQDKKITHTIVP 392
           PIDL+Y++G GS ++   PA    +RC + +      IP TVK+RTG  +   I   +V 
Sbjct: 387 PIDLLYRQGSGSALLDN-PA--RMIRCLNAMNYVSKDIPITVKIRTGTKEGHPIAEGLVK 443

Query: 393 KMSN-WGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPV----------------- 434
           ++ N    + IT+HGRSR+ RYTKS+DW+Y+   A                         
Sbjct: 444 RLVNETDVAAITLHGRSRQQRYTKSADWDYVSQVADTLRSAEADFIETEQGKEGRDSKNR 503

Query: 435 ---YGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEI 491
               GNGD+ ++ED+         +  VM+ RGALIKPWIF E++ Q+  D +S +R +I
Sbjct: 504 IQFVGNGDVNNFEDWYRYLNGNENIDSVMVARGALIKPWIFEEVESQQYLDKTSTERLDI 563

Query: 492 LKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVP 529
           L+ Y+ + +EHWG+D  G+   RRF  E++SF +RYVP
Sbjct: 564 LRDYAQFSMEHWGTDEYGISQCRRFFCEFMSFFHRYVP 601



 Score = 66.1 bits (154), Expect = 2e-09
 Identities = 55/223 (24%), Positives = 103/223 (46%), Gaps = 29/223 (13%)

Query: 7   GVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKN-DSKT 65
           G+  IK EY      I+  K    +K  + +   S D    EF       T  KN + + 
Sbjct: 28  GIAHIKPEY------IVPLKQNENQKVAIYDEEMSSDRMTNEFAGG----TNKKNKNGRG 77

Query: 66  KKRGQNKSRPKIFKDGKESKP-CPTILDVESSEQLKICQY-NNCKFIHDSKQFLNSKPKD 123
           KKRGQNK+R    +  KE    CP ++  + S+    C + +NC+F+HD   +L++K  +
Sbjct: 78  KKRGQNKNRDN--RQVKEQNVLCPRLIHGDISK----CSFGDNCRFVHDINLYLSTKKPE 131

Query: 124 IGDQ----CHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQ-----WK-DDTKNT 173
           +       C V+   G CP G  CR+ S H+  +   ++++++ D      W      N 
Sbjct: 132 VESNIFPSCPVFNSLGFCPMGFKCRFLSSHLNKEDNILISKKEIDPDAQTIWSVKGEVNH 191

Query: 174 LQPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADV 216
           + P  +  L K+++ F  + ++++ +D+  +    ++    +V
Sbjct: 192 ISPERKLDLIKRRFPFTKSNEILEIIDSFQQECRDSMKPEEEV 234


>UniRef50_Q2HDP2 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 641

 Score =  244 bits (596), Expect = 7e-63
 Identities = 140/328 (42%), Positives = 187/328 (57%), Gaps = 39/328 (11%)

Query: 302 FGAQICGNNPYIITKVAQLLQENT-ELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS 360
           FGAQI  N P++  K  + L +    L  +DLN GCP+D ++K G GS ++     LE  
Sbjct: 309 FGAQIAANAPWVAVKATEALSQLLPHLRLVDLNCGCPVDAVFKSGSGSALLDSHSKLERM 368

Query: 361 VRCASKLLS-IPFTVKMRTGVYQDKKITHTIVPKMSNW-----------GASLITVHGRS 408
           +R  + +   +P T K+R G    K     +V +++             G + +T+HGR+
Sbjct: 369 IRGMNAVSGEVPITAKIRMGSRDGKLTAQKLVERLALGSEDLRDMIGAPGCAAVTLHGRT 428

Query: 409 REARYT--------------------KSSDW-EYIETCAQAATPC--PVY--GNGDIFSY 443
           R  RYT                    KS+D  + I    +   P    +Y  GNGD +S+
Sbjct: 429 RLQRYTKAADWGYIAECAALIKQFNEKSNDLADTIREADENTLPNGGKMYFLGNGDCYSH 488

Query: 444 EDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHW 503
            +Y +    A  V  VMIGRGAL+KPW+F EI++ +  D SS +R   ++K+  YG+E W
Sbjct: 489 VEYFDHVDNAK-VDSVMIGRGALVKPWVFEEIEKGQYLDKSSSERLTYIEKFVRYGMEAW 547

Query: 504 GSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCT 563
           GSD  G+  TRRFLLE+LSF  RYVP+GLLER P  +NERPP Y GRDDLETL AS N  
Sbjct: 548 GSDELGLNYTRRFLLEFLSFFCRYVPIGLLERLPPNLNERPPAYRGRDDLETLFASKNYK 607

Query: 564 DWIKISEMLLGPVPDGFQFLPKHKANSY 591
           DWIKISEM LGP P GF+F PKHK+NSY
Sbjct: 608 DWIKISEMFLGPAPPGFKFQPKHKSNSY 635



 Score = 45.2 bits (102), Expect = 0.005
 Identities = 45/156 (28%), Positives = 67/156 (42%), Gaps = 23/156 (14%)

Query: 7   GVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKN----- 61
           GV  IK EY+L             +K K  +S A  DDN+ +  + +   T  +      
Sbjct: 48  GVAPIKAEYLLFPPG---------QKAKPTQSEAEADDNDDDAAEGRTAPTPQETQQAPQ 98

Query: 62  -DSKTK-KRGQNKSRP-KIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFLN 118
            D K K +RGQNK R    F D +  + C TI              + C  +HD +++L 
Sbjct: 99  KDGKRKSQRGQNKEREFGTFSDAQ--RLCNTIAWTPEFSPRPCKHGDRCNALHDLRKYLK 156

Query: 119 S-KPKDI---GDQCHVYKVRGKCPRGIACRYGSDHI 150
             +  DI   G +C V++  GKCP G  C +   H+
Sbjct: 157 EGRRPDITTFGGKCPVWEKYGKCPSGWRCLFVHSHM 192


>UniRef50_Q7X346 Cluster: Putative uncharacterized protein; n=1;
           uncultured Acidobacteria bacterium|Rep: Putative
           uncharacterized protein - uncultured Acidobacteria
           bacterium
          Length = 355

 Score =  200 bits (488), Expect = 8e-50
 Identities = 119/326 (36%), Positives = 168/326 (51%), Gaps = 6/326 (1%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308
           ++P+T   NLP+RR+C E GA +T  EM L   L +    E+AL++R   E  FG Q+ G
Sbjct: 1   MAPMTKGSNLPYRRLCVELGARITVSEMTLARRLKQKRNSEFALIRRFPGEPCFGVQLAG 60

Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC-ASKL 367
           N P   T  A  L E+   DF+D+N GCPID   +KG G+ +  +   +   V      +
Sbjct: 61  NKP-DETAWAAALVESRGADFVDINFGCPIDYFTRKGLGASIGRQPQRMRRLVEAIKGSV 119

Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427
            +IP T K+R G   D +          + GA+ + VHGR+R ARY  ++DW+ I     
Sbjct: 120 TNIPVTAKIRLGWNDDDRNYLQQAQAAVDGGAAALFVHGRTRNARYRFAADWDAIARIV- 178

Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKD 487
           AA P PV GNGD+    +    R+ +     VM+ R ALIKPWIF E  +   WDI++++
Sbjct: 179 AAVPVPVIGNGDLLFPHEIAAARERSGCA-AVMVARAALIKPWIFREAVD-GYWDITAEE 236

Query: 488 RFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTY 547
           R  + ++Y     EHWG D  G+   R FL   L F YRYVP  L +     +  R  T 
Sbjct: 237 RVGLYRRYVTLAREHWGDDEHGLARIRTFLNWHLEFWYRYVP-RLEDGTFASMQRRVDTV 295

Query: 548 FGRDDLETLMASSNCTDWIKISEMLL 573
             R  LE L+A  +      I+E LL
Sbjct: 296 PARSPLEALLARGDAAAKEYIAECLL 321


>UniRef50_A4S604 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 287

 Score =  197 bits (480), Expect = 8e-49
 Identities = 111/288 (38%), Positives = 157/288 (54%), Gaps = 6/288 (2%)

Query: 246 KLYLSPLTTVGNLPFRRIC-KEFGADVTCGEMALCESLLKGLKQEWALVKRHETE--DLF 302
           +L+L+PLT  GN PFRR+C  EFGA+V   EMA    L KG + E A V+RHE +  D F
Sbjct: 3   QLWLAPLTKGGNAPFRRLCASEFGAEVVVSEMAFARFLAKGARVERARVRRHEGDAGDCF 62

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
           GAQI  N        A +       DF+DLN GCPI   +K+G G+ ++ +   LE  V 
Sbjct: 63  GAQIATNAIEEGVNAALIASGEFGADFVDLNCGCPIHETWKRGLGAALLKKPAKLERLVE 122

Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
             +  + +P TVK+R G+    +    I   + N GAS + VHGR++E RYTK++D++ I
Sbjct: 123 GIASRIDVPLTVKIRLGIDSSSQ-ARRIAEGLENAGASAVVVHGRTKEQRYTKAADYDVI 181

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWD 482
               +     P+ GNGD+ ++ D  + R     V  +M+GRGALIKPWIF E +E+K W+
Sbjct: 182 RDIVRERN-IPIIGNGDVLTWYDARD-RMEHSGVAAMMVGRGALIKPWIFKEYRERKCWN 239

Query: 483 ISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPV 530
            + + R  +     NY  E +G D  G      F    L F  RY P+
Sbjct: 240 PTVEQRVGVYYTLRNYMREGFGDDELGKRRFDEFFPWHLGFFCRYRPL 287


>UniRef50_Q7R3K2 Cluster: GLP_158_4738_3071; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_158_4738_3071 - Giardia lamblia ATCC
           50803
          Length = 555

 Score =  183 bits (445), Expect = 1e-44
 Identities = 88/162 (54%), Positives = 116/162 (71%), Gaps = 3/162 (1%)

Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRF 489
           TP  + GNGDIF Y D    R    TV   +I RGAL+KPWIF EIKE +  D+SS+ R 
Sbjct: 391 TPPLLGGNGDIFDYTDL--HRDDHSTVDYYLIARGALVKPWIFQEIKEGRRIDMSSQSRL 448

Query: 490 EILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFG 549
           E+LK ++++ LE++GSD  GVE  R   LE  SF+ RY+PVG+L+  PQ++N+RPP + G
Sbjct: 449 EMLKLFASFCLEYYGSDAPGVEKARAQFLENWSFMCRYIPVGILDE-PQKLNQRPPMFRG 507

Query: 550 RDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591
           RD+LETLMAS + +DW+ ISEML GPVP GF F+PKHK++ Y
Sbjct: 508 RDELETLMASQSASDWVTISEMLFGPVPAGFSFVPKHKSHGY 549



 Score =  112 bits (270), Expect = 2e-23
 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           L L+P+ TVG +PFRR+C  +G ++T  EM     +L G  QE   +KRH  E  FG Q+
Sbjct: 176 LMLAPMCTVGTIPFRRLCIHYGCEITLCEMVFARDILHGDAQELRKIKRHPDEKCFGIQL 235

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC--- 363
            G    ++ ++   + +    DFIDLN  CP D+  KK  G+ +   L  L +SV C   
Sbjct: 236 AGRGQELM-EIVNFISQCCSCDFIDLNAACPQDIATKKCCGAALAANLKKLVSSVDCMVR 294

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
             +   +P  +K+R G  +      ++   +   G   ++VH R+ + RY+K ++W+Y+ 
Sbjct: 295 GGEHYGVPVFLKIRAGDLRGDWTGDSVAQALRLSGLYGLSVHLRTAKQRYSKLANWDYLV 354

Query: 424 TCAQAATPC 432
           +   A   C
Sbjct: 355 SMRHALDNC 363



 Score = 40.3 bits (90), Expect = 0.14
 Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 1/51 (1%)

Query: 100 KICQYNNCKFIHDSKQF-LNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDH 149
           K C+   C   HD  +F +   P      CH  K  GKCP  + C Y S H
Sbjct: 54  KQCKNPKCNAYHDLDEFSVYYTPPQTSISCHFLKTYGKCPFSVNCMYASSH 104


>UniRef50_A4XH30 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
           Putative TIM-barrel protein, nifR3 family -
           Caldicellulosiruptor saccharolyticus (strain ATCC 43494
           / DSM 8903)
          Length = 328

 Score =  157 bits (381), Expect = 8e-37
 Identities = 82/232 (35%), Positives = 126/232 (54%), Gaps = 2/232 (0%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305
           KL+L+P+    +  FR +C  FGADVT  EM   +++  G ++   L+   E E + G Q
Sbjct: 7   KLFLAPMAGFTDKVFRSLCSRFGADVTVTEMVSAKAITMGSQKTKELISFSEDEKIKGVQ 66

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
           I G++P+++ +  +++Q+  E DFID+N+GCP+  + K G GS +M         V   +
Sbjct: 67  IFGSDPHVMAEAVKIIQDEFEYDFIDINMGCPVPKVVKSGEGSALMKNPSLAAKIVEEVA 126

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425
           K+   P +VK+R G  ++          M   GAS ITVHGR+R   Y+  +DWE I+  
Sbjct: 127 KVSRKPVSVKIRKGFDEENINAPEFACIMQESGASFITVHGRTRTQMYSGKADWEIIK-M 185

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
            +     PV  NGDI  +E   +  +I      +MIGR AL  PW+F +IKE
Sbjct: 186 VKEKVKIPVVANGDIVDFESAKKAYEIT-EADSIMIGRAALGNPWVFLQIKE 236


>UniRef50_Q899H0 Cluster: Nitrogen regulation protein nifR3; n=24;
           Clostridia|Rep: Nitrogen regulation protein nifR3 -
           Clostridium tetani
          Length = 322

 Score =  144 bits (348), Expect = 8e-33
 Identities = 88/282 (31%), Positives = 137/282 (48%), Gaps = 8/282 (2%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETED 300
           ++    ++L+PL  V +L FR +CK  G  +   EM   ++L     +   +++  + E 
Sbjct: 6   LELKGNVFLAPLAGVTDLAFRGLCKRMGCTLVYTEMVSAKALFYDSDKTKDMLRFSKEEL 65

Query: 301 LFGAQICGNNPYIITKVAQ-LLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359
               QI G  P I+  V +     N  +  ID+N+GCP   I K G GS +M        
Sbjct: 66  PIAVQIFGKEPDIMANVVEKYFNSNDNVCLIDINMGCPAPKIVKNGEGSALMKNPKLASD 125

Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419
            V    K+ + P TVK R G   D          M N GA  +T+HGR+RE  Y   +DW
Sbjct: 126 IVESIKKVSTKPVTVKFRKGFDNDNINALEFAKIMENSGADALTIHGRTREQMYQGKADW 185

Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE-- 477
           E I+   + +   PV GNGD+F+ ED + M + +    GVM+ RGAL  PWIFN+I E  
Sbjct: 186 EIIKK-VKESVKIPVIGNGDVFTGEDAINMIE-STNCDGVMVARGALGNPWIFNQISEAL 243

Query: 478 --QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFL 517
             Q+I + S  +  E+  ++    L ++  + + V   R+ +
Sbjct: 244 KGQQILEPSPDEILEVCIEHFKRALYYY-DEKKAVREMRKHI 284


>UniRef50_A5BP75 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 940

 Score =  140 bits (339), Expect = 1e-31
 Identities = 61/87 (70%), Positives = 73/87 (83%)

Query: 505 SDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTD 564
           +D  GVE+TR F+LEWLS+ YRYVPVGLL+  PQ++N RPP+YFGRDDLETLMAS +  D
Sbjct: 570 ADDGGVETTRHFMLEWLSYTYRYVPVGLLDVIPQQLNWRPPSYFGRDDLETLMASDSAAD 629

Query: 565 WIKISEMLLGPVPDGFQFLPKHKANSY 591
           WI+ISEMLLG VP GF F PKHK+N+Y
Sbjct: 630 WIRISEMLLGKVPPGFSFAPKHKSNAY 656


>UniRef50_A6LGT0 Cluster: Putative TIM-barrel enzyme; n=1;
           Parabacteroides distasonis ATCC 8503|Rep: Putative
           TIM-barrel enzyme - Parabacteroides distasonis (strain
           ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 329

 Score =  138 bits (333), Expect = 5e-31
 Identities = 81/277 (29%), Positives = 141/277 (50%), Gaps = 9/277 (3%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           ++L+P+  V ++ FR +CK FGAD+   E    ++L++ + +    +   + E     QI
Sbjct: 13  VFLAPMEDVTDISFRLMCKRFGADMVYTEFVSSDALIRSVNKTQQKLNVSDDERPVAIQI 72

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
            G +   + + A++ +E    D +D+N GCP+  +  KG G+GM+  +P +    R   K
Sbjct: 73  YGKDVASMVEAARICEE-ARPDILDINFGCPVKKVAGKGAGAGMLRNIPLMLEITREVVK 131

Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426
            ++IP TVK R G   D ++   +  ++ + G + +++HGR+R   YT  +DW  I    
Sbjct: 132 AVNIPVTVKTRLGWDADNRVIVDLAEQLQDCGIAALSIHGRTRAQMYTGEADWTLIRAVK 191

Query: 427 -QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ-KIWDIS 484
                  P+ GNGD+ S E   + R     V  VMIGR ++ +PWIF E+K      ++ 
Sbjct: 192 NNPRMQIPIIGNGDVTSAE-ICKQRFEDYGVDAVMIGRASIGRPWIFREVKHYLTTGELL 250

Query: 485 SKDRF----EILKKYSNYGLEHWGSDTQGVESTRRFL 517
            ++ F    +ILKK     +E    + +G+   RR L
Sbjct: 251 PQEPFSWYLDILKKQVEQSVERL-DERRGILHIRRHL 286


>UniRef50_Q7MXX6 Cluster: TIM-barrel protein, putative, NifR3
           family; n=23; Bacteroidetes/Chlorobi group|Rep:
           TIM-barrel protein, putative, NifR3 family -
           Porphyromonas gingivalis (Bacteroides gingivalis)
          Length = 333

 Score =  136 bits (330), Expect = 1e-30
 Identities = 74/231 (32%), Positives = 124/231 (53%), Gaps = 3/231 (1%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           L L+P+  V ++ FR +CK+FGAD+   E    ++L++ +   +  +   E+E     QI
Sbjct: 13  LLLAPMEDVTDVAFRIMCKQFGADLVYSEFLSADALIRQVAGTFRKMAIDESERPMAVQI 72

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
            G +   + + A+L  E+   + IDLN GCP+  +  KG GSGM+  +P +    R   K
Sbjct: 73  YGRDVASMVEAARLC-ESAGPNLIDLNFGCPVKRVAGKGAGSGMLRNIPLMIEITREVVK 131

Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI-ETC 425
            + +P TVK R G   D KI   +  ++ + G + +T+HGR+R   YT ++DW  I E  
Sbjct: 132 AVKLPVTVKTRLGWDNDSKIIVDLAEQLQDCGIAALTIHGRTRAQMYTGTADWTLIGEVK 191

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
                  P+ GNGD+ + ++      +   V  VM+GR ++ +PWIF ++K
Sbjct: 192 NNPRMQIPIIGNGDVTTPQEARRAFDVY-GVDAVMVGRASIGQPWIFEDMK 241


>UniRef50_Q1IVR5 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=2; Acidobacteria|Rep: Dihydrouridine synthase
           TIM-barrel protein nifR3 - Acidobacteria bacterium
           (strain Ellin345)
          Length = 370

 Score =  135 bits (327), Expect = 3e-30
 Identities = 91/285 (31%), Positives = 149/285 (52%), Gaps = 22/285 (7%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGL-KQEWALVKRHET----EDLFG 303
           L+P+  V +  FRR  +  G    CG M    +   GL +   A  +R+ T    E    
Sbjct: 36  LAPMAGVTDTVFRRFIRNLGG---CGLMMTEFTSADGLARMREAKARRYLTFYGNERPIS 92

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
           AQ+ G++   +   A+++Q+    D +DLN+GCP   + K  GGSG++  LP ++     
Sbjct: 93  AQLFGSDAETLADAAKVVQD-LGFDLVDLNLGCPSKRVVKCNGGSGLLRDLPQIKVIFES 151

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITVHGRSREARYTKSSDWEYI 422
             K ++IPFTVK R G + +K++    + K++ N G + + +H R+RE  Y+  ++W +I
Sbjct: 152 VRKAVTIPFTVKFRAG-WNEKELVFLELAKLAENCGLNAVAMHARTREQGYSGQANWGWI 210

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIFNEIKEQKI- 480
               Q     PV GNGDI + ED   M  +A T    VMIGR A   PWIF +I++    
Sbjct: 211 ADLKQ-VVKIPVIGNGDIRTPEDAAAM--VAKTGCDAVMIGRSAASNPWIFRQIEQYTAT 267

Query: 481 --WDI-SSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLS 522
             +D+ +++DR+E+++ Y    +E   +DTQG E   +    W +
Sbjct: 268 GRYDLPTNEDRYEMIRMYFRMLIE---NDTQGAEGKMKQFASWFT 309


>UniRef50_Q0F181 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Mariprofundus ferrooxydans PV-1|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Mariprofundus ferrooxydans PV-1
          Length = 341

 Score =  135 bits (327), Expect = 3e-30
 Identities = 81/245 (33%), Positives = 125/245 (51%), Gaps = 4/245 (1%)

Query: 232 KLLPRERK-TIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEW 290
           +LLP  R  T   +N L L+P+  + +LPFRRICK FG  +   EM    ++  G ++  
Sbjct: 4   RLLPGFRLGTYMIDNPLVLAPMAGITDLPFRRICKRFGVGLMVTEMIASRAVDMGRERTE 63

Query: 291 ALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGM 350
            + +  + E     QI G++P  +T+ A+    +   DF+D+N+GCP+  I K+  GS M
Sbjct: 64  RMAELGDDEHPVSIQIAGSDPEFVTEAARWAVGHGA-DFVDINMGCPVKKICKQVAGSAM 122

Query: 351 MHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSRE 410
           +     +   +      + +P T+K+RTG     K    I     + G  L+TVHGR+R 
Sbjct: 123 LRDEALVARVLAAVVAAVDVPVTLKIRTGWDDQSKNVQNIARIAEDSGIQLLTVHGRTRA 182

Query: 411 ARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPW 470
             +   + WE I   A+AA   PV GNGDI   E   EM +++    GVM+GR     PW
Sbjct: 183 QMFHGHACWEDI-GLAKAAVSIPVIGNGDIVDAESAREMIRVS-NCDGVMVGRAVQGNPW 240

Query: 471 IFNEI 475
           +  E+
Sbjct: 241 VLGEV 245


>UniRef50_Q64MI4 Cluster: Putative TIM-barrel enzyme; n=3;
           Bacteroidales|Rep: Putative TIM-barrel enzyme -
           Bacteroides fragilis
          Length = 324

 Score =  133 bits (322), Expect = 1e-29
 Identities = 71/231 (30%), Positives = 121/231 (52%), Gaps = 3/231 (1%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           ++L+P+  V +  FR +CK+FGAD+   E    ++L++ + +    +   + E     QI
Sbjct: 13  VFLAPMEDVTDPAFRLMCKKFGADMVYTEFVSSDALIRSVNKTTQKLTICDEERPVAIQI 72

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
            G +   +   A++++E  + D +D+N GCP+  +  KG G+GM+  +P +    R    
Sbjct: 73  YGKDTEAMVGAARIVEE-AQPDILDINFGCPVKKVAGKGAGAGMLQNIPKMLEITRAVVD 131

Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI-ETC 425
            + IP TVK R G   D KI   +  ++ + G + + +HGR+R   YT  +DW  I E  
Sbjct: 132 AVKIPVTVKTRLGWDADHKIIVDLAEQLQDCGIAALAIHGRTRAQMYTGEADWTLIGEVK 191

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
                  P+ GNGD+ +     E  +    V  +MIGRG++ +PWIF E+K
Sbjct: 192 NNPRMHIPIIGNGDVTTAAGAKECFE-RYGVDAIMIGRGSIGRPWIFREVK 241


>UniRef50_Q9RDC6 Cluster: Putative uncharacterized protein SCO2497;
           n=5; Bacteria|Rep: Putative uncharacterized protein
           SCO2497 - Streptomyces coelicolor
          Length = 406

 Score =  132 bits (319), Expect = 3e-29
 Identities = 74/231 (32%), Positives = 123/231 (53%), Gaps = 6/231 (2%)

Query: 249 LSPLTTVGNLPFRRICKEF--GADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           L+P+  + N PFR +C+EF  G  +   EM    +L++  ++   L+    TE     Q+
Sbjct: 29  LAPMAGITNAPFRTLCREFSGGKGLFVSEMITTRALVERNEKTMQLIHFDATETPRSIQL 88

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR-CAS 365
            G +P  + K  +++ E    D IDLN GCP+  + +KGGGS + ++   L   VR   +
Sbjct: 89  YGVDPVTVGKAVRMIAEEGLADHIDLNFGCPVPKVTRKGGGSALPYKRHLLRAIVREAVT 148

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITVHGRSREARYTKSSDWEYIET 424
               +P T+KMR G+  D  +T+    +++   G + I +HGR+    Y  ++DW+ I  
Sbjct: 149 GAGDLPVTMKMRKGL-DDDHLTYLDAGRIAVEEGVTAIALHGRTTAQHYGGTADWDAIAR 207

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
             +     PV GNGDI+S ED + M +      GV++GRG L +PW+F ++
Sbjct: 208 LKEHVPEIPVLGNGDIWSAEDALRMVR-ETGCDGVVVGRGCLGRPWLFADL 257


>UniRef50_Q8GQD1 Cluster: NifR; n=5; Leptospira|Rep: NifR -
           Leptospira interrogans
          Length = 329

 Score =  132 bits (319), Expect = 3e-29
 Identities = 80/279 (28%), Positives = 146/279 (52%), Gaps = 7/279 (2%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305
           K+ LSP+  + + P RRIC++FGA  +  E    + L+    +   + +    E     Q
Sbjct: 12  KISLSPMAGISDSPTRRICRKFGAAFSYTEFVNTDELVHRAPKALKMFRYKLEERPITFQ 71

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
           I GN   II + A+++QE  + D IDLN+GC    +  +G G+G++ R       +    
Sbjct: 72  IFGNRLEIIAEAAEIIQE-LKPDIIDLNMGCSTRKVSLRGAGAGLLRRPLLAGKIIEAIK 130

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425
           K ++IP T K+R G     +    +   +   G   +TVHGR++E  YT  +DW+ I   
Sbjct: 131 KRVNIPVTAKIRIGWDSTSRNYLEVSKILEESGVDALTVHGRTKEMAYTGFADWDAIGE- 189

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISS 485
            +     P++GNGDI S+++    +     + GV+IGR A+  PWIF+ +K++   ++S 
Sbjct: 190 IKVNRKIPIFGNGDIKSFQE-ANFKIDKYLLDGVLIGRNAIGNPWIFSGVKKE---ELSW 245

Query: 486 KDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFL 524
            +   ++ ++  + +E +G +  G+   R+ L+++L+ L
Sbjct: 246 SEVLAVILQHLRWMIEDYGEEF-GLVLFRKHLVKYLNGL 283


>UniRef50_Q6F288 Cluster: TRNA dihydrouridine synthetase; n=3;
           Mollicutes|Rep: TRNA dihydrouridine synthetase -
           Mesoplasma florum (Acholeplasma florum)
          Length = 325

 Score =  132 bits (318), Expect = 3e-29
 Identities = 81/237 (34%), Positives = 116/237 (48%), Gaps = 5/237 (2%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETED 300
           ++   KL   P+  V N PFR I KE GAD+ C EM   E +    K+ ++++   + E 
Sbjct: 6   VEIKGKLVQGPMAGVSNPPFRLISKEKGADLVCAEMVSVEGMTHNNKKTFSMLAVEKKEH 65

Query: 301 LFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLI-YKKGGGSGMMHRLPALET 359
               QI GN+        + + EN + D IDLNIGCP   +  +   GS ++     +  
Sbjct: 66  PMSMQIFGNDVESFIVATKWIDENVDCDIIDLNIGCPAPKVAVRSASGSSLLKTPELIYD 125

Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKM-SNWGASLITVHGRSREARYTKSSD 418
            V+   +  S P T K+R G +  + +    V K+    GAS ITVHGR+R   Y+  +D
Sbjct: 126 IVKAVVENTSKPVTAKIRLG-WDKESVNAVEVSKLIEKAGASGITVHGRTRSEFYSGHAD 184

Query: 419 WEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
           WE I+   +A    PV GNGD+        M ++     GVMI RG    PWIF EI
Sbjct: 185 WEKIKEVKEAVN-IPVIGNGDVIDGPSAKAMLELT-GCDGVMISRGCQGNPWIFREI 239


>UniRef50_A1IF01 Cluster: Dihydrouridine synthase family protein;
           n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep:
           Dihydrouridine synthase family protein - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 326

 Score =  130 bits (314), Expect = 1e-28
 Identities = 79/262 (30%), Positives = 124/262 (47%), Gaps = 7/262 (2%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308
           L+PL  + + PFRR+ K  G  +   EM     L    ++  A+++    E  F  QI G
Sbjct: 14  LAPLAGITDAPFRRLAKAAGCALVYSEMVSSHGLFYQSEKTGAMLRTTPEEAPFAVQIFG 73

Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL 368
             P ++ + A ++Q +     ID+N GC +  I K G G+ +M  LP     ++     +
Sbjct: 74  GKPAVMGRAAAMVQASGA-HMIDINFGCSVKKILKSGAGAALMKDLPLAAEVIQAVRDAV 132

Query: 369 SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQA 428
           SIP T+KMR+G   D      +       G + + +H R+    +  ++DW  I    Q 
Sbjct: 133 SIPLTIKMRSGWNPDGSDAFHLAEIAEARGVNAVALHPRTATQGFGGTADWSLIAALKQ- 191

Query: 429 ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE----QKIWDIS 484
            T  PV GNGDI   ED   M         VM+GR A+  PWIF +I      + + + S
Sbjct: 192 RTGLPVIGNGDIVLPEDARRMLD-QTGCDAVMVGRAAIGAPWIFKQINACLAGKPVVEPS 250

Query: 485 SKDRFEILKKYSNYGLEHWGSD 506
            + RFE++ +Y N  + H+G D
Sbjct: 251 LEHRFEVMSEYINAMVAHYGED 272


>UniRef50_Q6AJZ5 Cluster: TRNA-dihydrouridine synthase; n=1;
           Desulfotalea psychrophila|Rep: TRNA-dihydrouridine
           synthase - Desulfotalea psychrophila
          Length = 328

 Score =  129 bits (312), Expect = 2e-28
 Identities = 79/231 (34%), Positives = 118/231 (51%), Gaps = 5/231 (2%)

Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLF 302
           +++   L+PL    +L FR +C +FGAD T  EM  C  L    ++   ++     E   
Sbjct: 9   FSSPFVLAPLAGYTDLSFRLLCHQFGADYTVSEMISCHGLFYNQQRTLEMLASLPEERPV 68

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             Q+ G  P I+ K A L+  + + D ID+N+GCP+  + KKG G+ +M         +R
Sbjct: 69  SFQLFGAEPDIMAK-ATLILNDFQPDMIDINMGCPVRKVTKKGAGAALMSTPELAYDVIR 127

Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
                  IP TVK R GV   +             GA+ + VHGR+R   ++  +D   I
Sbjct: 128 SVVDNTDIPVTVKFRAGVSSTELNGVEFGLMTERAGAAAVAVHGRTRAQAFSGVADRGII 187

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIF 472
           +   +A +  PV GNGDI SY+D ++M  +A T   GVM+GRGAL  PW+F
Sbjct: 188 KEVKEALS-IPVIGNGDILSYQDGLDM--MAETGCDGVMVGRGALGNPWVF 235


>UniRef50_Q1Q3Q8 Cluster: Strongly similar to tRNA-dihydrouridine
           synthase; n=1; Candidatus Kuenenia stuttgartiensis|Rep:
           Strongly similar to tRNA-dihydrouridine synthase -
           Candidatus Kuenenia stuttgartiensis
          Length = 341

 Score =  129 bits (311), Expect = 2e-28
 Identities = 79/259 (30%), Positives = 135/259 (52%), Gaps = 6/259 (2%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305
           +L L+P+    ++P+R IC+ FG  ++  E+     ++   K+ + L+   E E     Q
Sbjct: 34  ELILAPMAGFSDMPYRLICRRFGMSMSYTEVVSVSGIVWNNKKTFKLLDFKEEERPVTFQ 93

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
           + GN+   IT+  + + E    D ID+N+GC +  I  KG G+GM+     +       +
Sbjct: 94  VVGNDECQITEACKKI-EQLGPDIIDINMGCSVSDIAGKGAGAGMLKHPSKISKMFNNLT 152

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425
             LS+P T K+R G     +    +   +   GASLI VHGR+R   ++ ++DW+ I   
Sbjct: 153 GSLSVPVTGKIRLGWDHKTRNYIEVARILEENGASLIAVHGRTRSQYFSGAADWDAIAEV 212

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISS 485
            Q +   PV  NGD+ S  D  E++K      GVMIGR A+  PWIF   K+++  +IS 
Sbjct: 213 KQ-SVKIPVIANGDVRSVADIAEIKK-RTACDGVMIGRAAIGHPWIF-RYKDRE--NISG 267

Query: 486 KDRFEILKKYSNYGLEHWG 504
            ++ E+++ + +   E++G
Sbjct: 268 SEKIEMIRYHLDCMKEYYG 286


>UniRef50_Q8KB61 Cluster: TIM-barrel protein, nifR3 family; n=10;
           Chlorobiaceae|Rep: TIM-barrel protein, nifR3 family -
           Chlorobium tepidum
          Length = 352

 Score =  128 bits (310), Expect = 3e-28
 Identities = 92/305 (30%), Positives = 145/305 (47%), Gaps = 12/305 (3%)

Query: 240 TIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE 299
           TID +  + L+P+  V +  FR++CK+ GAD+   E    E+L +G+++    +   + E
Sbjct: 10  TIDIDRPIILAPMEDVTDRAFRQLCKQHGADIVYTEFISAEALRRGVEKSIRKITVADHE 69

Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359
                QI GN    + + A +  E  E D++D+N GCP+  +  +G G+ ++     L  
Sbjct: 70  RPVAVQIFGNTVESMVEAAAIA-ETYEPDYLDINFGCPVKKVAGRGAGAALLKEPEKLSE 128

Query: 360 SVRCASKLLSIPFTVKMRTGVYQDK-KITHTIVPKMSNWGASLITVHGRSREARYTKSSD 418
                   +S+P T K R G   D   IT T V ++ + G   + VHGR+R   Y   +D
Sbjct: 129 IASAVVNAVSLPVTAKTRIGWDHDSINITDT-VRRLEDAGIRAVAVHGRTRSDMYKGRAD 187

Query: 419 WEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE- 477
           W  I    QA +  PV  NGD++  ED V M +      G+MIGRG++  P+IF + K  
Sbjct: 188 WGRIAEAKQACS-IPVIANGDVWLPEDAVAMFE-RTGADGIMIGRGSIGNPFIFEQAKSL 245

Query: 478 ----QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPV-GL 532
                ++   S + R +    +    LE+ G +  GV   RR    +L  L     V  L
Sbjct: 246 VKEGVRLSAPSYRQRIQAAVDHLRLSLEYKG-EKYGVLEMRRHYSTYLKGLPGVSKVRNL 304

Query: 533 LERPP 537
           L R P
Sbjct: 305 LVREP 309


>UniRef50_Q6MRF1 Cluster: Transcription regulator homolog yacF; n=1;
           Bdellovibrio bacteriovorus|Rep: Transcription regulator
           homolog yacF - Bdellovibrio bacteriovorus
          Length = 337

 Score =  128 bits (310), Expect = 3e-28
 Identities = 73/228 (32%), Positives = 113/228 (49%), Gaps = 3/228 (1%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N   L+P+  + +  FR   K+  A V   E+     +     +   L+   E++   G 
Sbjct: 10  NPFVLAPMAGITDHAFRTFIKKLDASVVVTELVSASGIEYKSDRTLKLMSFDESQRPIGI 69

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G  P I+ + AQ+ + +   DF+DLN GCP+  + KKG GS ++    A++  V   
Sbjct: 70  QLFGEEPEIVARAAQVAEADG-CDFVDLNFGCPVPKVVKKGAGSAILKDPAAVQKMVSTV 128

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
              + IP T+K+RTG   + +    I     N G S + +HGR+R   YT  +DW++I  
Sbjct: 129 KAAIKIPLTIKIRTGWDANSRNATEICNIAYNEGVSWVAIHGRTRAQSYTGLADWDFIAD 188

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
             +A T  P+ GNGDI +      +R       GVMIGRG L  P+IF
Sbjct: 189 -VKANTKIPILGNGDILTPRQ-ANLRLQQSGCDGVMIGRGCLKNPFIF 234


>UniRef50_Q0YFW9 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=8; Desulfuromonadales|Rep: Dihydrouridine
           synthase TIM-barrel protein nifR3 - Geobacter sp. FRC-32
          Length = 343

 Score =  128 bits (310), Expect = 3e-28
 Identities = 77/237 (32%), Positives = 128/237 (54%), Gaps = 8/237 (3%)

Query: 240 TIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE 299
           ++   N L L+P+  + NLP R + +E GA +T  EM     L++  K+ + L++R   +
Sbjct: 26  SLQLENNLILAPMAGLTNLPMRILARECGAALTFTEMISVNGLVREGKKTFDLLRRDPMD 85

Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359
              G QI G++P ++ + A+L+++  EL  ID+N+GCP+  +   G GS ++     +  
Sbjct: 86  RPMGIQIFGDDPQLLAEGARLVEQYGEL--IDINMGCPVRKVVGSGAGSALLREPAKVGM 143

Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSN-WGASLITVHGRSREARYTKSSD 418
            ++   K  S+P T+K+RTG +     T   + +++   G   +T+H RSR   +   +D
Sbjct: 144 IIKAVRKATSLPLTIKIRTG-WGAADHTFLEIGRIAEAEGVDGVTLHPRSRAQMFEGHAD 202

Query: 419 WEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIFNE 474
           W  I    +A +  PV G+GDIF+  D V M  I  T   GVM+ RG L  PW+F E
Sbjct: 203 WSRIRELKEALS-IPVIGSGDIFTAADVVAM--IDQTGCDGVMVARGGLGNPWLFRE 256


>UniRef50_Q1NXZ7 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3 precursor; n=2; delta proteobacterium MLMS-1|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3
           precursor - delta proteobacterium MLMS-1
          Length = 313

 Score =  128 bits (309), Expect = 4e-28
 Identities = 81/235 (34%), Positives = 122/235 (51%), Gaps = 8/235 (3%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           L  +PL    +LPFR +C+E+GA +   EM  C  L++       ++     E     Q+
Sbjct: 15  LVAAPLAGYSDLPFRLLCREYGAGLCYSEMLSCHGLVRRQPATIEMLATTAAERPLLMQL 74

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
            G  P ++ + A +L     +D ID+N+GCP+  + KKG G+ +M R P L  ++  A  
Sbjct: 75  FGAEPEVMGEAAAIL-SRLPIDGIDINMGCPVRKVVKKGAGAALM-RDPELAAAITGAVT 132

Query: 367 LLS--IPFTVKMRTGVYQDKKITHTIVPK-MSNWGASLITVHGRSREARYTKSSDWEYIE 423
             +  +P TVK+R+G +  K+I      + +   GA+ +T+H R+    +T  +DW  I 
Sbjct: 133 AAAGDLPVTVKIRSG-WNHKQINAPDFARLLVAHGAAAVTIHARTWSDGFTGRADWAVI- 190

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478
              + A   PV GNGDI SYE  + M   A    GVMIGRGAL  PW+F    EQ
Sbjct: 191 AAVKRAVSVPVIGNGDIGSYEQALAM-MAATGCDGVMIGRGALGAPWVFTPGAEQ 244


>UniRef50_Q2RZL4 Cluster: NifR3 family enzyme; n=1; Salinibacter
           ruber DSM 13855|Rep: NifR3 family enzyme - Salinibacter
           ruber (strain DSM 13855)
          Length = 443

 Score =  128 bits (308), Expect = 5e-28
 Identities = 74/238 (31%), Positives = 118/238 (49%), Gaps = 4/238 (1%)

Query: 241 IDWNNK-LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE 299
           +D++++ L+L+P+  V + PFR +CK +GAD+   E      LL+  + E   ++  + E
Sbjct: 70  LDFDDRPLFLAPMEDVSDPPFRILCKRYGADMMYTEFVSSAGLLREQEHEHQKLEIFDEE 129

Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359
              G Q+ G     +     ++ +    D ID+N GCP+  I +K GG+G++  L  +  
Sbjct: 130 RPIGIQVWGGGIDEVRNATPMV-DAAGPDVIDINFGCPVRKIVQKDGGAGVLRNLDKMRN 188

Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419
                 +  + P TVK R G   D      +   + + G + +TVH R+RE +Y   + W
Sbjct: 189 ITAAVMEEATRPVTVKTRLGWDDDSIHIVDVARMLEDMGVAALTVHARTREQKYKGDARW 248

Query: 420 EYIETCAQAAT-PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
           E++ T  +  T   P  GNGD    E  +E       V GVM+GRGAL  PWIF   K
Sbjct: 249 EWLRTIKEEGTRDMPFIGNGDALDPE-AIEAMFEETGVDGVMLGRGALGNPWIFERAK 305


>UniRef50_Q2IG49 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=2; Anaeromyxobacter|Rep: Dihydrouridine
           synthase TIM-barrel protein nifR3 - Anaeromyxobacter
           dehalogenans (strain 2CP-C)
          Length = 352

 Score =  128 bits (308), Expect = 5e-28
 Identities = 71/231 (30%), Positives = 113/231 (48%), Gaps = 3/231 (1%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305
           + +L+PL  V + PFR IC+  GA     EM     L+ G  Q  + + R   ED F  Q
Sbjct: 11  RYFLAPLAGVSDRPFRAICRRMGASFAYTEMVSAHGLMHGALQTSSYLDREPDEDPFAVQ 70

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
           I  + P ++ + A ++        ID+N+ CP+  +   G G+ M      +E +VR   
Sbjct: 71  IFASEPDVLARGA-VVAVQAGAGMIDVNMACPVKKVCGSGAGAAMGRDPRKVEEAVRAIR 129

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425
             + +P TVK+R G  + +     +       GA+ + +HGR+R   Y+  + WE +   
Sbjct: 130 AAVPVPVTVKIRAGWDEGEVNCVDVARAAEAGGAAAVALHGRTRSQLYSGKARWELVRAV 189

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
            QA    PV G+GD+++  D V MR+       V++ RGA   PWIF E+K
Sbjct: 190 KQAVA-IPVLGSGDVWTAGDAVRMRE-ETGCDAVLVARGACGNPWIFRELK 238


>UniRef50_A6CBK4 Cluster: Predicted TIM-barrel enzyme, possibly
           dehydrogenase, nifR3 family protein; n=1; Planctomyces
           maris DSM 8797|Rep: Predicted TIM-barrel enzyme,
           possibly dehydrogenase, nifR3 family protein -
           Planctomyces maris DSM 8797
          Length = 365

 Score =  127 bits (306), Expect = 9e-28
 Identities = 85/264 (32%), Positives = 132/264 (50%), Gaps = 10/264 (3%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLKGLKQEWALVKRHETEDLFG 303
           ++  LSPL    NLPFRRI +E G   +   ++     LL+G ++   L +    +  F 
Sbjct: 28  SRYLLSPLAGYTNLPFRRIVRELGGVGLATTDLVNARGLLEGSEKTLQLTQTCPEDSPFA 87

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
            QI G+ P  +   AQLL E+  +  ID+N+GCP++ I K G G+ MM R     + V+ 
Sbjct: 88  VQIFGSEPQQMKDAAQLL-ESRGVHSIDINMGCPVNRIVKGGAGASMMCRPSDTVSLVQT 146

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPK-MSNWGASLITVHGRSREARYTKSSDWEYI 422
             + + IP +VKMR G + D +++     +     G   + +HGR+RE  +    + + I
Sbjct: 147 VVEAVKIPVSVKMRLG-WDDSELSAPFFSREFEKVGVVAVAIHGRTREQGFRGVVNHDGI 205

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI---KEQK 479
               +A    PV GNGD+ +  +   M K      GV IGRGAL  PWIF ++   ++  
Sbjct: 206 RRVVEAVDSIPVIGNGDVTNVAEADFMLKTTGCA-GVSIGRGALANPWIFRQLVQWEQTG 264

Query: 480 IWDISSK--DRFEILKKYSNYGLE 501
            +D      DR E+L +   Y LE
Sbjct: 265 TYDPPGNFDDRLELLLRQFRYLLE 288


>UniRef50_Q9Z7D8 Cluster: Predicted oxidoreductase; n=7;
           Chlamydiaceae|Rep: Predicted oxidoreductase - Chlamydia
           pneumoniae (Chlamydophila pneumoniae)
          Length = 335

 Score =  126 bits (304), Expect = 2e-27
 Identities = 91/282 (32%), Positives = 134/282 (47%), Gaps = 7/282 (2%)

Query: 239 KTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHET 298
           K I   + +  +PL    + P+R +   +   +   EM   E +L   ++   L+  +E 
Sbjct: 8   KNILLRSSIVYAPLAGFSDYPYRCMSALYQPGLMFCEMVKVEGILYAPERTSKLLDYNEN 67

Query: 299 EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALE 358
               GAQ+CG+NP    + A++L E    D IDLN GCP D I K G GSG++     + 
Sbjct: 68  MRPIGAQLCGSNPETSGEAAKIL-EGLGFDLIDLNCGCPTDKITKDGSGSGLLKTPELIG 126

Query: 359 TSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSD 418
             +      +SIP TVK+R+G   +       V  + + GAS + VHGR+R   Y   S 
Sbjct: 127 RILDKIINSVSIPVTVKIRSGWDMEHINVEDTVRIIRDAGASAVFVHGRTRAQGYHGPSK 186

Query: 419 WEYIETC-AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
            EYI    A A    PV+GNGDIFS E    M  +     GV++ RG L  PWI  +I  
Sbjct: 187 QEYISRAKAAAGKEFPVFGNGDIFSPEAAQAM--LTTGCDGVLVARGTLGAPWIGKQI-- 242

Query: 478 QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLE 519
           Q      S ++   +K+ + + LEH        +S  +FL E
Sbjct: 243 QDYLTTGSYEKIPFIKRKAAF-LEHMRLVEDYYQSETKFLSE 283


>UniRef50_Q5M689 Cluster: Possible transcriptional regulator; n=20;
           Streptococcus|Rep: Possible transcriptional regulator -
           Streptococcus thermophilus (strain ATCC BAA-250 / LMG
           18311)
          Length = 350

 Score =  126 bits (304), Expect = 2e-27
 Identities = 73/231 (31%), Positives = 118/231 (51%), Gaps = 2/231 (0%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           ++  L+P+  V N  FR I KEF A +   EM   + LL   ++   ++   E E     
Sbjct: 42  HRTVLAPMAGVTNSAFRTIAKEFSAGLVVMEMISEKGLLYNNEKTLHMLHIDENEHPMSI 101

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G +   + + A  +Q NT+ D +D+N+GCP++ + K   G+  +     +   V+  
Sbjct: 102 QLFGGDAEGLKRAADFIQTNTKADIVDINMGCPVNKVVKNEAGAKWLKDPDKIYHIVKEV 161

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
           + +L IP TVKMRTG + D  +         + G S + +HGR+RE  YT   D E +  
Sbjct: 162 TSVLDIPLTVKMRTG-WSDSDLAVENALAAESAGVSALAMHGRTREQMYTGHCDHETLAR 220

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
            A+A T  P  GNGD+ + +D  ++      V  VM+GR A+  P+IF +I
Sbjct: 221 VAKAITKIPFIGNGDVRNVQD-AKLMIEELGVDAVMVGRAAMNNPYIFTQI 270


>UniRef50_Q74EF7 Cluster: Dihydrouridine synthase family protein;
           n=2; Deltaproteobacteria|Rep: Dihydrouridine synthase
           family protein - Geobacter sulfurreducens
          Length = 325

 Score =  125 bits (302), Expect = 3e-27
 Identities = 74/230 (32%), Positives = 116/230 (50%), Gaps = 4/230 (1%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N L L+P+  + NLPFR + +E GA +   EM     L++  K+ + L++    +   G 
Sbjct: 14  NNLILAPMAGITNLPFRLLAREQGAGLCFTEMVSVNGLVREGKKSFELLRSVPGDRPLGI 73

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G++P ++ +VA  +    +L  ID+N+GCP+  +   G GS +M     +   VR  
Sbjct: 74  QLFGDDPDVMGRVAATVDGYGDL--IDINMGCPVKKVVGTGAGSALMREPDKVRAIVRAV 131

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
            +   +P TVK+R+G   +      I       G + +T+H RSR   +  ++DW  +  
Sbjct: 132 RRATRLPLTVKIRSGWSCEDANFIQIARIAEEEGCNAVTLHPRSRAQMFEGTADWTKLAE 191

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
             QA    PV G+GD+FS  D   M        GVMI RGAL  PWIF +
Sbjct: 192 LKQAVA-IPVIGSGDLFSAADVAAMLD-RTGCDGVMIARGALGNPWIFRQ 239


>UniRef50_A2FJB5 Cluster: TIM-barrel protein, nifR3 family protein;
           n=1; Trichomonas vaginalis G3|Rep: TIM-barrel protein,
           nifR3 family protein - Trichomonas vaginalis G3
          Length = 301

 Score =  125 bits (302), Expect = 3e-27
 Identities = 73/221 (33%), Positives = 119/221 (53%), Gaps = 5/221 (2%)

Query: 257 NLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITK 316
           ++ FR +  E GAD+T  EM    +L+   K+   L+     E     QI G++P ++ +
Sbjct: 6   DIAFREVATEKGADITVTEMVSAMALVYENKKTIDLLDISPKEKKVAVQIFGSDPDVMGE 65

Query: 317 VAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKM 376
            A++L +  +  ++D+N+GCP   I K   GS ++     +   V+   K  + P T K+
Sbjct: 66  AARILNDY-DFSYVDINMGCPAPKIVKNNSGSHLLSNPSLVYDIVKSVVKNSNKPVTAKV 124

Query: 377 RTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYG 436
           R G+     +    +  +   GAS +TVHGR+RE  YT  +DW++I+   +     PV G
Sbjct: 125 RKGIGGVSSMK--AIKNIEAAGASFVTVHGRTREEYYTGKADWDFIKE-VKENVKIPVIG 181

Query: 437 NGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
           NGD+ S ED +E    +  V G+ IGRGA+  P+IFN+I+E
Sbjct: 182 NGDVDSPEDAIEKINYS-KVDGLAIGRGAIGNPYIFNQIEE 221


>UniRef50_A5D5Q0 Cluster: TRNA-dihydrouridine synthase; n=5;
           Firmicutes|Rep: TRNA-dihydrouridine synthase -
           Pelotomaculum thermopropionicum SI
          Length = 324

 Score =  125 bits (301), Expect = 4e-27
 Identities = 74/228 (32%), Positives = 113/228 (49%), Gaps = 3/228 (1%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N +  +P+  + +  FR + +EFG  + C EM   ++LL G  +  +L+           
Sbjct: 10  NPVIAAPMAGITDKAFRILAREFGCGLVCTEMVSDQALLHGNPKTCSLLDVAGEAGPVSV 69

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           QI G+N   + + A +  E+     ID+N+GCP   I K G G+ +M         VR  
Sbjct: 70  QIFGSNAACMAEAAGIA-ESRGAGIIDINMGCPTPKIVKNGEGAALMREPEKAARIVRAV 128

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
            + + +P TVKMR G   +      +    +  GA+ +TVHGR+R   Y   +DWE I  
Sbjct: 129 VERVKVPVTVKMRKGWDDNSPNAVELARLAAEAGAAAVTVHGRTRSQLYAGKADWEII-A 187

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
             + A   PV GNGD+++ +D + M +      GVMIGR AL  PWIF
Sbjct: 188 AVKRAVDVPVIGNGDVWTPQDALAMLE-QTGCDGVMIGRAALGNPWIF 234


>UniRef50_O25427 Cluster: Probable tRNA-dihydrouridine synthase;
           n=9; Epsilonproteobacteria|Rep: Probable
           tRNA-dihydrouridine synthase - Helicobacter pylori
           (Campylobacter pylori)
          Length = 328

 Score =  124 bits (298), Expect = 9e-27
 Identities = 80/240 (33%), Positives = 124/240 (51%), Gaps = 8/240 (3%)

Query: 241 IDWNNK--LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHET 298
           +D+ NK  L+L+PL    +LPFR + K+FG DVT  EM    SL+    +   ++++   
Sbjct: 1   MDFKNKKWLFLAPLAGYTDLPFRSVVKKFGVDVTTSEMVSSHSLVYAFDKTSKMLEKSPL 60

Query: 299 EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALE 358
           ED F AQI G+   ++ +  + +     ++ ID N GCP   +   G GSG++  L  L 
Sbjct: 61  EDHFMAQISGSKESVVKEAVEKINALEHVNGIDFNCGCPAPKVANHGNGSGLLKDLNHLV 120

Query: 359 TSVRCASKLLSIPFT-VKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSS 417
             ++   +  S   T VK+R G   +KKI   I   +++     + VHGR+R  +Y K  
Sbjct: 121 KLLKTIRENTSKKITSVKVRLGF--EKKIPKEIAHALNDAPVDYVVVHGRTRSDKYQKDK 178

Query: 418 -DWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
            D+E I    +     PV  NG+I S +   E+ +I     G+MIGR AL  PWIF +I+
Sbjct: 179 IDYESIALMKKILKK-PVIANGEIDSVKKAFEVLQIT-QADGLMIGRAALRAPWIFWQIR 236


>UniRef50_Q1VN28 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Psychroflexus torquis ATCC 700755|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Psychroflexus torquis ATCC 700755
          Length = 338

 Score =  123 bits (296), Expect = 2e-26
 Identities = 72/235 (30%), Positives = 116/235 (49%), Gaps = 4/235 (1%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           ++L+P+  V +L +R + KE GAD T  E      L +     W  V+    E  F  QI
Sbjct: 14  IFLAPMAGVTDLAYRLLAKECGADFTVTEFTAASGLTRKNTNSWLKVETDPREKPFIPQI 73

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
            G +   + K   +L++ +  D ID+N GCP   + +   G+ ++     + + VR   +
Sbjct: 74  FGGDISEMAKTVGMLEDRS--DVIDINFGCPAPKVCRNDAGAALLRDPDKVVSMVRRCIE 131

Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426
             ++P TVKMR G          I  ++++ G   I VHGR+   RY+  +DW+ I+  +
Sbjct: 132 STNVPITVKMRLGTGSGPNTALEISKRLADEGVMRICVHGRTLRQRYSGIADWDQIKEIS 191

Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIW 481
             +   PV  NGD+   +   E+   A    G+MIGRGA+ +P IF+EIK    W
Sbjct: 192 N-SVDIPVIANGDVVDTKS-AELCLEATNAGGLMIGRGAIGRPTIFHEIKHGMGW 244


>UniRef50_Q9ZED2 Cluster: Probable tRNA-dihydrouridine synthase;
           n=39; Proteobacteria|Rep: Probable tRNA-dihydrouridine
           synthase - Rickettsia prowazekii
          Length = 327

 Score =  123 bits (296), Expect = 2e-26
 Identities = 81/290 (27%), Positives = 143/290 (49%), Gaps = 15/290 (5%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVK-RHETE 299
           I+ ++ + L+P++ V +L FR++ K FGA +   EM    +++   +Q        H+  
Sbjct: 7   IELSSNVILAPMSDVTDLEFRKLVKRFGAGLVVSEMIASRAMIMKSRQSMQKCAIMHDDP 66

Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359
                Q+ G  P +I + A++  E+     IDLN GCP   +     GS +M        
Sbjct: 67  TSACVQLAGCEPDVIAEAAKM-NEDMGAKIIDLNFGCPAKKVVGGYAGSALMRDEQLAAK 125

Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419
                 K + IP TVKMR G   + +   T+    +N G  ++TVHGR+R   Y+ +++W
Sbjct: 126 IFEATVKAVKIPVTVKMRIGWDDNTRNAPTLAKIAANSGVQMVTVHGRTRCQFYSGNANW 185

Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI---- 475
           ++I T  + A   PV  NGDI ++    E  +      G+M+GRG   KPW+ ++I    
Sbjct: 186 DFIRT-VKEAVKIPVIANGDITNFAKAKEALQ-RSGADGIMVGRGVYGKPWLISQIAYYL 243

Query: 476 ---KEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLS 522
              KE+    I+  ++ +I+ K+ +  ++++G    GV   R+ ++ W S
Sbjct: 244 KTGKEKPAPSIA--EQLDIITKHYDAIIDYYGKSV-GVPIARKHII-WYS 289


>UniRef50_A6EDJ3 Cluster: Probable TIM-barrel protein, NifR3 family;
           n=1; Pedobacter sp. BAL39|Rep: Probable TIM-barrel
           protein, NifR3 family - Pedobacter sp. BAL39
          Length = 335

 Score =  122 bits (294), Expect = 3e-26
 Identities = 69/231 (29%), Positives = 112/231 (48%), Gaps = 3/231 (1%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           L L+P+  V + PFR +CK+ G D+   E    E L++   +  A +   E E   G QI
Sbjct: 15  LLLAPMEDVSDPPFRFVCKQSGVDMMYTEFISSEGLIRDAAKSRAKLDIFEYERPIGIQI 74

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
            G+    + +  ++       D +D+N GCP+  +  +G GS ++  +  +    +    
Sbjct: 75  FGSEIDHMREATEIASMAGP-DLMDINYGCPVKQVACRGAGSALLQDIDKMVEMTKAVVN 133

Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI-ETC 425
              +P TVK R G   + K    +  ++ + G   +T+HGR+R   Y   +DW  I E  
Sbjct: 134 ATHLPVTVKTRLGWDDNTKNVEEVAERLQDIGIQGLTIHGRTRAQMYKGEADWTLIREIK 193

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
                  P++GNGD+ S +   + R +   V G+MIGR A+  PWIF EIK
Sbjct: 194 RNPRIKIPIFGNGDVDSIQKAADWR-LEYEVDGIMIGRAAIGYPWIFREIK 243


>UniRef50_P37567 Cluster: Probable tRNA-dihydrouridine synthase 1;
           n=31; Bacilli|Rep: Probable tRNA-dihydrouridine synthase
           1 - Bacillus subtilis
          Length = 333

 Score =  122 bits (293), Expect = 4e-26
 Identities = 72/231 (31%), Positives = 112/231 (48%), Gaps = 2/231 (0%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETED 300
           I   N++ L+P+  V N  FR   KEFGA + C EM   +++L    +   ++   E E 
Sbjct: 7   IQLKNRVVLAPMAGVCNSAFRLTVKEFGAGLVCAEMVSDKAILYNNARTMGMLYIDEREK 66

Query: 301 LFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS 360
               QI G     + + A+ + +NT  D ID+N+GCP+  I K   G+  +     +   
Sbjct: 67  PLSLQIFGGKKETLVEAAKFVDQNTTADIIDINMGCPVPKITKCDAGAKWLLDPDKIYEM 126

Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420
           V      ++ P TVKMR G  +D          +   G   + +HGR+R   Y  +++W+
Sbjct: 127 VSAVVDAVNKPVTVKMRMGWDEDHIFAVKNAQAVERAGGKAVALHGRTRVQMYEGTANWD 186

Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWI 471
            I+   Q+ +  PV GNGD+ + +D   M      V GVMIGR AL  PW+
Sbjct: 187 IIKEVKQSVS-IPVIGNGDVKTPQDAKRMLD-ETGVDGVMIGRAALGNPWM 235


>UniRef50_A4TZK1 Cluster: Dihydrouridine synthase, DuS; n=4;
           Proteobacteria|Rep: Dihydrouridine synthase, DuS -
           Magnetospirillum gryphiswaldense
          Length = 335

 Score =  121 bits (291), Expect = 6e-26
 Identities = 76/285 (26%), Positives = 142/285 (49%), Gaps = 13/285 (4%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N + L+P++ V ++P RR+ K  GA +   EM   +++++  +Q   +      E     
Sbjct: 18  NPVILAPMSGVTDMPCRRLVKRMGAGLVVSEMIASQAMIRANRQTMKMASNCAEEHPMSV 77

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG-GGSGMMHRLPALETSVRC 363
           Q+ G  P ++ + A+ +  +     ID+N+GCP+  +  KG  GS +M         +  
Sbjct: 78  QLAGCEPEVMAEAAR-MNADRGAAIIDINMGCPVKKVAVKGEAGSALMKDEILAGQLMEA 136

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
             + + +P T+K R G   ++     +       G  ++T+HGR+R+  YT ++DW+++ 
Sbjct: 137 TVRAVDVPVTLKCRMGWDHNRLNAPRLARIAQESGIKMVTIHGRTRQQFYTGTADWKFVR 196

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIFNEIKE----- 477
              + A   PV  NGDI + +D +  R +A +   GVMIGRG+  +PW   ++       
Sbjct: 197 Q-VKDAVDIPVIVNGDIETIDDAI--RALAESGADGVMIGRGSYGRPWFPGQVAHYLATG 253

Query: 478 QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLS 522
           ++  D +   +  IL ++ +  L H+G+DT GV   R+  + W S
Sbjct: 254 ERPADPALDQQLAILLEHFDDMLSHYGTDT-GVRMARKH-IAWYS 296


>UniRef50_A4EC62 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 347

 Score =  120 bits (289), Expect = 1e-25
 Identities = 68/230 (29%), Positives = 103/230 (44%), Gaps = 4/230 (1%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308
           ++P+  V +  +R +C+  GA++   EM     L     + W LV   + E     Q+ G
Sbjct: 21  MAPMAGVTDPAYRIMCRRRGANLAYSEMVSVAGLAYASNKTWRLVLPADEEQQICVQLFG 80

Query: 309 NNPYIITKVAQLLQENT--ELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
           + P         ++E     L  ID+N+ CP   +  KG GS +M      E  V  A  
Sbjct: 81  SKPEQFASAVAAVEERVGDRLSLIDINMACPARKVVTKGEGSALMRTPDLAEKIVEAAVG 140

Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426
              +P TVK+R G Y + +   T    +   GA+ + VHGR     YT  +DW  ++  A
Sbjct: 141 AAHVPVTVKIRKGFYAEDRNAATFAQMLEGAGAAAVAVHGRCATQLYTGQADWSVVDEVA 200

Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
             A   PV G+GD+FS ED  E  +       V I RG    PW+F + +
Sbjct: 201 D-AVEIPVIGSGDVFSAEDAAEHLQ-GSGASAVFIARGIYGNPWVFGDAR 248


>UniRef50_O67533 Cluster: Probable tRNA-dihydrouridine synthase;
           n=1; Aquifex aeolicus|Rep: Probable tRNA-dihydrouridine
           synthase - Aquifex aeolicus
          Length = 316

 Score =  120 bits (289), Expect = 1e-25
 Identities = 73/251 (29%), Positives = 129/251 (51%), Gaps = 10/251 (3%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK-GLKQEWALVKRHETEDLFGA 304
           ++ L+P+ +  +  FRR+C+  GAD T  E+     +L+ G+  + A     E E     
Sbjct: 7   EVILAPMASYTHSAFRRLCRRLGADRTYTELISAVGVLRNGIPMKLAYFT--EEERPIHI 64

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC- 363
           Q+ G+NP  I + + ++ +  + DFID+N GC +  + +      M+   P +   V+  
Sbjct: 65  QVFGSNPEEIAQASVVIAKELKPDFIDINFGCSVPKVLRNKAAGYMLQCPPLMGEVVKET 124

Query: 364 --ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
             A K   IP + K+R G  +D+     IV ++   G SLI +H R+ +  ++  + W  
Sbjct: 125 VEALKPYGIPVSAKIRLGFEKDE--VERIVEELQKAGVSLIAIHARTAKQGFSGKALWHR 182

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIW 481
           I+   + A+  P+ G+GD+ S+ D   M +      GVM+GR AL  PWIF E KE++  
Sbjct: 183 IKEAKKVAS-VPIIGSGDVKSWRDIERMFE-ETECDGVMVGRAALSNPWIFKEFKEKRDI 240

Query: 482 DISSKDRFEIL 492
           ++  K+R + +
Sbjct: 241 EVGLKERMDFI 251


>UniRef50_Q8G7W8 Cluster: Possible NifR3-like protein; n=4;
           Bifidobacterium|Rep: Possible NifR3-like protein -
           Bifidobacterium longum
          Length = 414

 Score =  119 bits (287), Expect = 2e-25
 Identities = 76/250 (30%), Positives = 118/250 (47%), Gaps = 6/250 (2%)

Query: 231 IKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGAD-VTCGEMALCESLLKGLKQE 289
           + + P +   I     + LSP+  V N PFR IC+E+G D +   EM    +L+    + 
Sbjct: 33  VHIAPVQLGNITVPTPVVLSPMAGVTNWPFRVICEEYGPDGLYVAEMITARALVAHNPKA 92

Query: 290 WALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSG 349
             L    ++E +   Q+ G NP I  + A+++ +    D +DLN GCP+  + ++GGGS 
Sbjct: 93  LRLCHFAKSEKIRSLQLYGVNPSITEQAAKIVVDGNMADHVDLNFGCPVPKVTRRGGGSA 152

Query: 350 MMHR---LPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHG 406
           +  +      L   V    +   IP T K+R G+  + +            G   +T+H 
Sbjct: 153 LPWKTDIFTELLQRVVAVCEPAGIPVTAKIRVGIDHNHETFLEAGHIAQEEGCKAVTLHA 212

Query: 407 RSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGAL 466
           R+    Y   SDW  I    +     PV+GNGDI+  ED +EM +      GV IGRG  
Sbjct: 213 RTTAEYYGGHSDWSRIGELKEHLN-IPVFGNGDIWGAEDALEMVR-ETGCDGVAIGRGCQ 270

Query: 467 IKPWIFNEIK 476
            +PW+F  IK
Sbjct: 271 GRPWLFANIK 280


>UniRef50_A5EVV4 Cluster: Dihydrouridine synthase; n=1;
           Dichelobacter nodosus VCS1703A|Rep: Dihydrouridine
           synthase - Dichelobacter nodosus (strain VCS1703A)
          Length = 318

 Score =  117 bits (282), Expect = 8e-25
 Identities = 67/230 (29%), Positives = 119/230 (51%), Gaps = 6/230 (2%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFG--AQI 306
           L+P+  + +LP+R +C+ FG+  T  EM         + +   L  + + +  F    Q+
Sbjct: 16  LAPMAGISDLPYRSLCQRFGSHYTIAEMVDARPQFLAMPES-QLRLQFDDDARFPKIVQL 74

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
            G +PY++ + AQ++Q     D ID+N+GCP   + K+  GS ++  LP +E  +   ++
Sbjct: 75  VGGDPYLMAETAQVMQA-LGCDVIDINMGCPAKKVGKQNAGSALLSDLPQVEKILAQVTR 133

Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426
           ++SIP T+K R G  +      T+     N G + +TVHGR+R  R+  ++ ++ I    
Sbjct: 134 VVSIPVTLKTRLGFNEQTMTIETVAKIAENTGVAALTVHGRTRAQRFNGTAHYDEIGR-V 192

Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
           +A T  P+  NGDI +     ++ +      GVMIGR A   PW+   ++
Sbjct: 193 KAQTSLPIIVNGDITTTAQAQDLIQ-QFGFDGVMIGRAACGNPWLLAHMR 241


>UniRef50_Q6A959 Cluster: TIM-barrel enzyme, NifR3 family; n=1;
           Propionibacterium acnes|Rep: TIM-barrel enzyme, NifR3
           family - Propionibacterium acnes
          Length = 411

 Score =  116 bits (279), Expect = 2e-24
 Identities = 73/254 (28%), Positives = 127/254 (50%), Gaps = 9/254 (3%)

Query: 229 DLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQ 288
           D + L+     T+  +  + L+P+  V N  FR++C E GA +   EM     L+ G  +
Sbjct: 34  DPLTLIAPSGGTVSVDTPVVLAPMAGVTNAAFRQLCAEQGAGLYVCEMITSRGLVYGDHK 93

Query: 289 EWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGS 348
              ++   E ED+   Q+ G +P ++ +   +L E   ++ +DLN GCP+  + +KGGG 
Sbjct: 94  THGMLAFAECEDVRSVQLYGVDPGMVGEATSILCEKYGVNHVDLNFGCPVPKVTRKGGGG 153

Query: 349 GM---MHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITV 404
            +   + R  A+ ++   A     +P TVK R G+   + IT+    + + + GA+ + +
Sbjct: 154 VLPWKLDRFAAVVSAAVQAGDAHGVPVTVKTRIGI-DPEHITYIDSARAAVDSGAAAVCL 212

Query: 405 HGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGR 463
           H R+    Y   S W+ I    +     PV GNGDI+   D + M  +  T   GV +GR
Sbjct: 213 HARTVAEAYAGHSHWDAIGELVK-TVDVPVIGNGDIWEASDAMAM--VGQTGCAGVEVGR 269

Query: 464 GALIKPWIFNEIKE 477
           G L +PW+F ++ +
Sbjct: 270 GCLGRPWLFRDLAD 283


>UniRef50_A4M5I1 Cluster: Dihydrouridine synthase, DuS; n=1;
           Petrotoga mobilis SJ95|Rep: Dihydrouridine synthase, DuS
           - Petrotoga mobilis SJ95
          Length = 301

 Score =  115 bits (277), Expect = 3e-24
 Identities = 75/278 (26%), Positives = 139/278 (50%), Gaps = 11/278 (3%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N++ L+P+    + PFR IC+ FGA  T  EM   +S+++  ++   ++ + + ED  G 
Sbjct: 4   NQIGLAPMADYTDYPFREICRRFGAKFTFTEMISVDSIIRENEKVEKMLPQ-KGEDNIGV 62

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ GN      + A+ +Q      +ID+N  CP++ + KKG G+ ++     L   V   
Sbjct: 63  QLFGNETTKFIEAAKSIQHLAS--WIDINAACPVNKVVKKGSGAALLKNPKLLGDIVFNL 120

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
            K + +P  VK+R G   D+     +   +   GA  I VHGR+R   Y+  ++ E ++ 
Sbjct: 121 KKSIDLPVGVKVRLG--YDQINIEEVAETVEKAGADYIIVHGRTRSQMYSGIANREILKK 178

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDIS 484
             +A    P+  +GD+FS +D ++   +      V++ RGA+  PWIF +       D  
Sbjct: 179 -LKAKITIPLGASGDVFSKKD-IDDYLLNYGADFVLVARGAIGNPWIFTKNNYNPTID-- 234

Query: 485 SKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLS 522
             +R +   ++    +E +GS+   V+  R+ L+++ S
Sbjct: 235 --ERIDTCLEHLKLMIEFYGSEVYAVKKFRKVLMKYFS 270


>UniRef50_A6PPM6 Cluster: Dihydrouridine synthase, DuS; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Dihydrouridine
           synthase, DuS - Victivallis vadensis ATCC BAA-548
          Length = 343

 Score =  115 bits (276), Expect = 4e-24
 Identities = 75/278 (26%), Positives = 131/278 (47%), Gaps = 4/278 (1%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N L ++PL+   +LP+RR  +  G      EM    SL    ++   +++R   E+  G 
Sbjct: 16  NALLMAPLSGFTDLPYRRAARAGGCRFAFTEMVDVASLTYARERSAGMLRRGPEEEFLGV 75

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G +   I + A ++ E  E   +D N+GCP+  + KKG G+ +   L A        
Sbjct: 76  QLVGADHEFIRRAADVVNEY-EFSVVDFNLGCPVPKVAKKGAGAELGRHLDAALACFAII 134

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
           ++    P T K+R    +D   T  +   ++  GA  ITVHGR +EA Y+   ++  I  
Sbjct: 135 AERSRHPVTAKIRIVDAEDPAPTLALAKGLAELGAQAITVHGRIKEAFYSGPVNFGMIRA 194

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDIS 484
             +A     V  NG +     Y E+R+       VM+ RGA+  PW+FNE+     +   
Sbjct: 195 VREALPGVQVIANGGVTGRVKYQEIRR-ETGCSLVMLARGAMGNPWLFNELSLGDAYVPP 253

Query: 485 SKDR-FEILKKYSNYGLEHWGSDTQGVESTRRFLLEWL 521
             D  F +++++    +E +G ++  +   R+ L ++L
Sbjct: 254 DIDEWFGVIREHVEGMIELYGEES-AMRMARKILHDYL 290


>UniRef50_Q9CLW3 Cluster: tRNA-dihydrouridine synthase B; n=17;
           Pasteurellaceae|Rep: tRNA-dihydrouridine synthase B -
           Pasteurella multocida
          Length = 332

 Score =  115 bits (276), Expect = 4e-24
 Identities = 64/228 (28%), Positives = 115/228 (50%), Gaps = 3/228 (1%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N+++L+P+  + + PFRRIC  +GA +T  EM      +   ++    +  H+   +   
Sbjct: 10  NRIFLAPMAGITDQPFRRICTHYGAGLTFSEMMSTNPQVWHTEKSKLRLAHHQEAGINAV 69

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           QI G +P  + K AQ+  E    + ID+N+GCP   + +K  GS ++     ++  +   
Sbjct: 70  QIAGCDPDEMAKAAQINVEYGA-EIIDINMGCPAKKVNRKMAGSALLQYPDLVKQILNKV 128

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
            K +++P T+K+RTG  +D +    I       G   +T+HGR+R   +   ++++ I+ 
Sbjct: 129 VKSVTVPVTLKIRTGWDKDNRNCLEIAKIAEQCGIQALTIHGRTRSCMFEGEAEYDNIKA 188

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
             +  +  P+  NGDI S E    +         +MIGRG+L  PW+F
Sbjct: 189 VKEQLS-IPIIANGDITSAEKAKYVLDYT-NADAIMIGRGSLGNPWLF 234


>UniRef50_A0LJ96 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Syntrophobacter fumaroxidans MPOB|Rep: Putative
           TIM-barrel protein, nifR3 family - Syntrophobacter
           fumaroxidans (strain DSM 10017 / MPOB)
          Length = 352

 Score =  113 bits (273), Expect = 9e-24
 Identities = 70/234 (29%), Positives = 117/234 (50%), Gaps = 6/234 (2%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKR-HETEDLFGAQ 305
           L L+P+  V +  +R +  +FGA +   EM   + L++  +    L ++ H        Q
Sbjct: 24  LVLAPMAGVTDSAYRALMADFGAAMVTTEMVSIQGLVRNQRATLDLCRQQHPVGVPLAVQ 83

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
           + G +P ++ + A+L+++      ID+N GCP+  + ++G G+ ++     L   V    
Sbjct: 84  VFGRDPAVMAEAARLVEQGGAA-LIDINAGCPVRKVVRQGAGAILLKDPDRLAAMVEAVK 142

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425
           + +S+P TVK+R G          +  ++ + G   ITVHGR+    Y+  +DW  I   
Sbjct: 143 RAVSVPVTVKIRVGWDNAANGVAGLARQLVSAGVDAITVHGRTAAQMYSGRADWSRIAE- 201

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIFNEIKEQ 478
            +AA   PV GNGD+ S E  +  R I  T   GVMIGR +L  PW+F  I  +
Sbjct: 202 VKAAVAVPVIGNGDVTSPE--LAERMIHETGCDGVMIGRASLGNPWLFAVISRR 253


>UniRef50_Q2RM54 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Moorella thermoacetica ATCC 39073|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Moorella thermoacetica (strain ATCC 39073)
          Length = 334

 Score =  113 bits (272), Expect = 1e-23
 Identities = 74/232 (31%), Positives = 108/232 (46%), Gaps = 6/232 (2%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           L ++P+    +  FR + +E GA +T  EM   + L+   K   AL+           Q+
Sbjct: 16  LIMAPMAGYTDRVFRLLAREAGAALTYTEMISAQGLIYNNKNTHALLDLKGEPGPVAVQL 75

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
            G  P I+    ++         IDLN+GCP   I K G GS +M  LP     V    +
Sbjct: 76  FGREPEIMAAATRIAVA-AGAAIIDLNMGCPTPKIVKNGEGSALMRDLPRAAAIVAAMVR 134

Query: 367 LLS-IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425
               +P TVKMR G  +D          +   GA+ + +HGR+R   Y+  +DW Y    
Sbjct: 135 AAGPVPVTVKMRLGWDEDSINVVEAARAVVYAGAAAVAIHGRTRSQFYSGRADWSYFRR- 193

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIFNEIK 476
            + A   PV GNGD+ +  D V M  +A T   GVM+GRGA+  PW+   I+
Sbjct: 194 VKEAVDVPVIGNGDVRTARDAVTM--LAETGCDGVMVGRGAVGNPWLLTAIR 243


>UniRef50_A6NW05 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 307

 Score =  113 bits (272), Expect = 1e-23
 Identities = 72/226 (31%), Positives = 109/226 (48%), Gaps = 9/226 (3%)

Query: 255 VGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYII 314
           V ++ FR IC+E GA  T  EM   ++L    K+   L+K  E E    AQI G++   +
Sbjct: 4   VTDMAFRTICRELGAGYTITEMVSAKALCYQDKKSIPLLKLGEGEHPCAAQIFGSDEKCM 63

Query: 315 TKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL----SI 370
            + A +  E +  D ID+N+GCP+  +   G GSG+M     ++ +VR A  ++      
Sbjct: 64  EEAAAIAGEVSGADIIDINMGCPVPKVANSGDGSGLMR---DVDKAVRVAEAVVRGAGER 120

Query: 371 PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAAT 430
           P TVK R G  +           M   G S + VHGR+R   Y  +++W+YI    QA +
Sbjct: 121 PVTVKFRLGWDKGSINCVEFAKAMEAAGVSAVAVHGRTRTQMYAGTANWDYIREVKQAVS 180

Query: 431 PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
             PV  NGD+F       + +        MIGRG    PW+F + +
Sbjct: 181 -IPVIANGDVFDGPAAAHILRYT-GADMAMIGRGCFGNPWVFQQAR 224


>UniRef50_Q3E0H8 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=5; Chloroflexi (class)|Rep: Dihydrouridine
           synthase TIM-barrel protein nifR3 - Chloroflexus
           aurantiacus J-10-fl
          Length = 407

 Score =  113 bits (271), Expect = 2e-23
 Identities = 73/233 (31%), Positives = 115/233 (49%), Gaps = 6/233 (2%)

Query: 247 LYLSPLTTVGNLPFRR-ICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305
           + L+P+  V +  FRR I +  G  +   EM    S+     +   L+     E     Q
Sbjct: 85  IILAPMAGVTDSIFRRMILRLGGCGLVSTEMTNAASVSPKALRRHRLLDYLPEERPLTMQ 144

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
           I GN+P ++   A+++ E    D ID+N GCP   +   G GS ++  LP +E  +R   
Sbjct: 145 ISGNDPDLVANAARVV-EQLGADIIDINCGCPSPKVTGGGHGSALLRDLPKMERLLRAVR 203

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSN-WGASLITVHGRSREARYTKSSDWEYIET 424
           + + IP T+K R G + ++ +      K +   G S + +H R+RE  Y   +DW  +  
Sbjct: 204 EAVQIPVTLKFRAG-WDEQSLNFIEAGKRAEAAGVSALALHPRTREQGYKGQADWSRVAA 262

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
             QA +  PV G+GD+ S  D + +R       GVMIGRGA+  PWIF +I +
Sbjct: 263 LKQAVS-IPVIGSGDVTSAHDAL-IRLRDSGADGVMIGRGAMANPWIFRQIAD 313


>UniRef50_Q0B0N8 Cluster: Putative TIM-barrel protein, NifR3 family;
           n=2; Clostridiales|Rep: Putative TIM-barrel protein,
           NifR3 family - Syntrophomonas wolfei subsp. wolfei
           (strain Goettingen)
          Length = 318

 Score =  113 bits (271), Expect = 2e-23
 Identities = 70/233 (30%), Positives = 115/233 (49%), Gaps = 3/233 (1%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N++  +P+  V +  +R + ++FG  + C EM   + L+ G  +   +      +     
Sbjct: 11  NRVCAAPMAGVSDKAYRVLARDFGCGLVCSEMVSDKGLVYGQGRTSKIADSSGEKRPVAV 70

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           QI G+    +   A++++E    D ID+N+GCP   I K G G+ +M  +      VR  
Sbjct: 71  QIFGSEAESMATAARIVEE-MGADIIDINMGCPTPKIVKNGEGAALMLDITKSRGIVREV 129

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
            +++ +P TVKMR G  ++      +  K+   G + I +H RSR+  ++ S+DW  I+ 
Sbjct: 130 LRVVKVPVTVKMRKGWDENSINCLELAQKLEEEGVAAICLHPRSRQQFFSGSADWNLIKE 189

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
             +     PV GNGDI+S +D   M         VMIGR AL  P+IF E  E
Sbjct: 190 -MKKELKIPVIGNGDIWSADDAQRMIDFT-GCDAVMIGRAALGNPFIFRETFE 240


>UniRef50_Q489F6 Cluster: NifR3/Smm1 family protein; n=2;
           Proteobacteria|Rep: NifR3/Smm1 family protein -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 338

 Score =  112 bits (270), Expect = 2e-23
 Identities = 68/236 (28%), Positives = 118/236 (50%), Gaps = 3/236 (1%)

Query: 240 TIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE 299
           T   N+++ L+P+  + + PFR++C + GA +   EM      +   ++    +   +  
Sbjct: 5   TYQLNSQVMLAPMAGITDQPFRQLCCQLGAGLAVSEMLSSNPKVWNTEKSKLRMLHGDAA 64

Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359
            +   QI G+ P  +   A++  +N     ID+N+GCP   + KK  GS ++     +E 
Sbjct: 65  GIRSVQIAGSCPDELAFAAKVNADNGA-QIIDINMGCPAKKVNKKLAGSALLREPAQVER 123

Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419
            V+     + IP T+K+RTG  +D +    I     N G + + VHGR+R   Y  ++++
Sbjct: 124 IVQSVVNAVDIPVTLKIRTGWCEDTRNGIEIAKIAENSGIASLAVHGRTRNDFYKGNAEY 183

Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
           + I+   + A   PV  NGDI S E  +++         +M+GRGA  +PWIF EI
Sbjct: 184 DTIK-AIKLAISIPVVANGDITSPEKALQVLD-HTGADAIMVGRGAQGRPWIFREI 237


>UniRef50_A6BZR9 Cluster: Predicted TIM-barrel enzyme, possibly
           dehydrogenase, nifR3 family protein; n=1; Planctomyces
           maris DSM 8797|Rep: Predicted TIM-barrel enzyme,
           possibly dehydrogenase, nifR3 family protein -
           Planctomyces maris DSM 8797
          Length = 355

 Score =  112 bits (270), Expect = 2e-23
 Identities = 74/234 (31%), Positives = 113/234 (48%), Gaps = 3/234 (1%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCG-EMALCESLLKGLKQEWALVKRHETEDLFG 303
           ++ +L+PL       FR   +E G    C  ++ L   LL G ++  AL+     +    
Sbjct: 23  SRYFLAPLAGYTQHAFRVAIRELGGVGLCTTDLVLASHLLSGSRKSKALLTTSPADRPLT 82

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
            QI G     +   A+ L+++     +DLN+GCP+  I   GGG+ +M    A    V  
Sbjct: 83  IQIFGGITAELVAAARWLEQHGYAA-VDLNMGCPMAKINGNGGGARIMCAPDAACQLVAE 141

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
               +SIP TVKMR G  +D      +  +    G + ITVHGR+R   +  + D + I 
Sbjct: 142 VVDAVSIPVTVKMRLGWDRDSITAPLLAREFEQAGVAAITVHGRTRNQGFGGTVDLQGIR 201

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
              +A    PV GNGD+ + ED   MR+     + V IGRGA++ PWIF +I +
Sbjct: 202 QTVEAVQQIPVIGNGDVCTVEDAFRMRE-QTGCEAVSIGRGAMLDPWIFRKISQ 254


>UniRef50_A6DCX2 Cluster: tRNA-dihydrouridine synthase B; n=1;
           Caminibacter mediatlanticus TB-2|Rep:
           tRNA-dihydrouridine synthase B - Caminibacter
           mediatlanticus TB-2
          Length = 311

 Score =  112 bits (269), Expect = 3e-23
 Identities = 72/259 (27%), Positives = 128/259 (49%), Gaps = 8/259 (3%)

Query: 248 YLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQIC 307
           +L+PL    +LPFR + KEFG D+T  EM    ++    ++   ++++   E  +  QI 
Sbjct: 14  FLAPLAGYTDLPFRSVVKEFGCDMTFSEMINANAIAFNNEKTKKMMQKSSKETPYFIQIA 73

Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM--HRLPALETSVRCAS 365
            NN     K  +++ E   +D ID+N+GCP++   + G G  ++       L+  V    
Sbjct: 74  ANNVENAIKAVEIINEIPWIDGIDINLGCPVNKARRSGYGGVLLKDENKEKLKEIVSAII 133

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425
           K      + KMR G   ++ +       + + G   +TVHGR+ +  Y  +++++ I+  
Sbjct: 134 KTSKKIVSAKMRLG--YNEVVAVDRAKMLEDLGIKFLTVHGRTVKQMYKGNANYKEIKKV 191

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISS 485
            +     PV  NGDI  Y+   E+ +      GV IGRG + KPWIF E+K+Q   +I+ 
Sbjct: 192 VKEVN-IPVIANGDITDYKKAKEVLEYT-EANGVAIGRGVIGKPWIFLEMKQQ--GEITP 247

Query: 486 KDRFEILKKYSNYGLEHWG 504
             + E++  +    +E +G
Sbjct: 248 YQKKEVILTHFKAMIEWYG 266


>UniRef50_Q8PX79 Cluster: NifR3-like protein; n=5; Archaea|Rep:
           NifR3-like protein - Methanosarcina mazei
           (Methanosarcina frisia)
          Length = 323

 Score =  111 bits (268), Expect = 4e-23
 Identities = 71/233 (30%), Positives = 118/233 (50%), Gaps = 4/233 (1%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFG 303
           +  L L+P+  V NL FR +C+ +GAD+T  EM   ++LL   ++ +      E +  FG
Sbjct: 14  SGNLLLAPMADVTNLAFRLLCRRYGADLTYTEMINVDALLNESRKSFIKGLSSEEDRPFG 73

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
            Q+ G  P  + + A  ++E    + ID+N+GCP   I   G GS +++    + + +  
Sbjct: 74  VQLVGGCPDKLKRAALFIEEEYRPEIIDVNMGCPARCITGAGCGSALLNSPELVYSIILE 133

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
            ++ L  P + K+R    ++K  T  I   +   GAS +TVHGR+    Y+ +S+ E I 
Sbjct: 134 LTESLDTPVSAKIRLLGREEK--TLEIARLIEKAGASAVTVHGRTAAQMYSGNSNLEGIR 191

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
                 +  PV  NGD+   E+  E         G+MIGR A+  P+IF +I+
Sbjct: 192 AVKNELS-IPVIANGDV-KDEESAERTLELTGCDGLMIGRAAMGNPFIFKKIR 242


>UniRef50_Q6M9N8 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 297

 Score =  111 bits (267), Expect = 5e-23
 Identities = 61/174 (35%), Positives = 92/174 (52%), Gaps = 4/174 (2%)

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
           G Q+CG+ P I  + A++++E    D +DLN GCP+D I K G GSG++ + P L   + 
Sbjct: 28  GGQLCGSKPSIAGQAAKIIEE-LGFDIVDLNCGCPVDKITKDGSGSGLL-KTPELIGEIV 85

Query: 363 CAS-KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
           C     + IP TVK+R G  + +     IV  +   GA  I +HGR+R+  Y   ++WEY
Sbjct: 86  CNMVSAVKIPVTVKIRAGWDEQQIQVENIVQIVEQAGAQAICIHGRTRQQGYRGPANWEY 145

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
           I+    AA    + GNGD+       +M         V++ RG L +PWI  +I
Sbjct: 146 IKRGKLAAKSIKIIGNGDVLDGPSAAKM-FCETGCDAVLVARGTLGQPWIVQDI 198


>UniRef50_Q6SFW7 Cluster: NifR3/Smm1 family protein; n=1; uncultured
           bacterium 578|Rep: NifR3/Smm1 family protein -
           uncultured bacterium 578
          Length = 322

 Score =  111 bits (267), Expect = 5e-23
 Identities = 68/233 (29%), Positives = 115/233 (49%), Gaps = 5/233 (2%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCES-LLKGLKQEWALVKRHETEDLF 302
           ++K+ L+P+    + PFR IC+E GA +T  EM + +  LL   K +  L  R E   + 
Sbjct: 9   SSKVLLAPMAGTSDKPFRMICREQGAALTTSEMVVMQKHLLNTNKSKHRLDFRSEQSPI- 67

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             QI G+    + + A+   E    D ID+N+GCP   +  K  GS +M     +E  ++
Sbjct: 68  SIQIAGSESQELAESAKQALE-FGADIIDINMGCPAKKVCNKAAGSALMKNEKLVEDIIK 126

Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
                ++IP T+KMRTG  ++ K   TI     + G  ++ +HGR+R  +Y   ++++ +
Sbjct: 127 AVVNAVNIPVTLKMRTGWNEENKNAPTIAKIAEDNGIKMLAIHGRTRAQKYNGDAEYDTV 186

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
           +   +     PV  NGDI S +   ++         VM+GR     PW+  +I
Sbjct: 187 KK-IKGIVSIPVVANGDITSAQKAKKVLDYT-GADAVMLGRATQGNPWLVGQI 237


>UniRef50_Q6MAU6 Cluster: Putative uncharacterized protein yohI;
           n=1; Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein yohI - Protochlamydia
           amoebophila (strain UWE25)
          Length = 326

 Score =  109 bits (261), Expect = 3e-22
 Identities = 83/268 (30%), Positives = 132/268 (49%), Gaps = 23/268 (8%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLKGLKQEWALVKRHETEDLF--- 302
           L L+P+  VG+  FR+     G  D  C E     S         +L  R+E  + F   
Sbjct: 14  LILAPMEGVGDRSFRKAMASVGGFDEACTEFMRVPSNA----HVPSLANRYEANETFPIP 69

Query: 303 -GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361
             AQ+ G++P ++ ++A+ + E      IDLN GCP + +  +G GS ++     L    
Sbjct: 70  QAAQLMGSDPELMAEMARAV-ERRGAQRIDLNCGCPSNTVTGRGAGSSLLKEPDHLYKVA 128

Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
           +   + +++P T K+R+G + D  + H  +      G   +T+H R++   Y   + WE 
Sbjct: 129 KSMVEAVNVPVTAKLRSG-FTDTSLFHDNLLAAQASGIKYLTLHPRTKVDGYGPPAKWEL 187

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE---- 477
           I   A+     PV GNGDI + +D + M K      G+MIGRG++I P+IF+EIK     
Sbjct: 188 IAQ-AKQLLKIPVVGNGDILTVQDALNMLK-QTKCDGLMIGRGSVINPFIFHEIKSHFSA 245

Query: 478 ---QKIWDISSK--DRF-EILKKYSNYG 499
              +K WD+ S+  D F E LK+ S  G
Sbjct: 246 QPFEKKWDVFSRYIDVFTEDLKEMSVKG 273


>UniRef50_Q251N6 Cluster: Putative uncharacterized protein; n=2;
           Desulfitobacterium hafniense|Rep: Putative
           uncharacterized protein - Desulfitobacterium hafniense
           (strain Y51)
          Length = 326

 Score =  107 bits (258), Expect = 6e-22
 Identities = 65/228 (28%), Positives = 112/228 (49%), Gaps = 3/228 (1%)

Query: 248 YLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQIC 307
           +L+P+  V +  FR   +  G      EM   ++L     +   ++           Q+ 
Sbjct: 18  FLAPMAGVTDKAFRETVRSVGGLHVWTEMISDKALTYMNSRTLEMLDLSGEASPRIVQLF 77

Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367
           G+ P ++ K A L  E  + + ID+N+GCP   I K G GS ++  LP  +       K 
Sbjct: 78  GSEPEVMAKAAALAVER-DAEIIDINMGCPTPKIVKNGEGSALLQDLPLAQRIAEAVVKA 136

Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427
           + +P TVKMR G   ++ +   +  ++   G  +++VHGR+RE  Y  +++ + I+   +
Sbjct: 137 VEVPVTVKMRLGWTAERIVAPELAKRVEAVGVQMVSVHGRTREQFYAGTANRDGIKK-VK 195

Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
                PV  NGDIFS ++   + + A    GVM+GRG+L  PW+  +I
Sbjct: 196 GGVSIPVIANGDIFSPQEAKTVLE-ATGCDGVMVGRGSLGNPWLIPQI 242


>UniRef50_Q31II6 Cluster: Dihydrouridine synthase; n=1;
           Thiomicrospira crunogena XCL-2|Rep: Dihydrouridine
           synthase - Thiomicrospira crunogena (strain XCL-2)
          Length = 320

 Score =  107 bits (257), Expect = 8e-22
 Identities = 70/228 (30%), Positives = 109/228 (47%), Gaps = 5/228 (2%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK-GLKQEWALVKRHETEDLFGAQIC 307
           L+P+  + +  +R IC+E GA     EM   +  L+   K       + ET      Q+ 
Sbjct: 14  LAPMAGITDRVYRDICRESGASYAVSEMVASKKQLRESAKSSTRHADKTETSPRI-VQLL 72

Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367
           G +P  +   A L Q++   D IDLN+GCP   +     GS +M +   +    +  ++ 
Sbjct: 73  GTHPEELVDAA-LWQQSQGADIIDLNMGCPAKKVCDVAAGSALMGQPERVADIFKSLTEA 131

Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427
           + +P TVK+RTG   D      I       G   IT+HGR+R  ++   ++++ I+   Q
Sbjct: 132 IDLPVTVKIRTGTDVDNINAVEIAKLAQELGLKAITIHGRTRADKFNGQAEYDTIKAVKQ 191

Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
            A   PV  NGDI S ++   + K   +  G+MIGR A   PWIF EI
Sbjct: 192 -AVDIPVIANGDICSPKEAQFVLKYTGS-DGIMIGRAAQGYPWIFREI 237


>UniRef50_A4YUQ6 Cluster: Putative tRNA-dihydrouridine synthase;
           n=4; Rhizobiales|Rep: Putative tRNA-dihydrouridine
           synthase - Bradyrhizobium sp. (strain ORS278)
          Length = 317

 Score =  107 bits (257), Expect = 8e-22
 Identities = 71/226 (31%), Positives = 107/226 (47%), Gaps = 8/226 (3%)

Query: 252 LTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDL--FGAQICGN 309
           ++ + + PFRR+  E GA +   EM   + L++G    W    R E   +     Q+ G 
Sbjct: 1   MSGITDAPFRRLAAELGAGLVVSEMTASDDLVRG---RWISRLRCEAGGIGPHVVQLAGC 57

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369
             + + + A++  +    D ID+N+GCP   +     GS +M  L    T +    + + 
Sbjct: 58  EAHWMAEGAKVAADGGA-DIIDINMGCPARHVTGGQSGSALMRDLDHALTLIEATVEAVD 116

Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429
           +P T+KMR G  +       +  +    G  LITVHGR+R+  Y   +DW  +    Q A
Sbjct: 117 VPVTLKMRLGWDERSLNAPELARRAEAAGVQLITVHGRTRQQFYKGEADWSAVRAVKQ-A 175

Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
              PV  NGDI SYED  E    A     VMIGRGA  +PW+  +I
Sbjct: 176 VDLPVVVNGDITSYEDAREALD-ASGADAVMIGRGAQGQPWLPGQI 220


>UniRef50_Q0G7A4 Cluster: Nitrogen regulation protein nifr3; n=2;
           Aurantimonadaceae|Rep: Nitrogen regulation protein nifr3
           - Fulvimarina pelagi HTCC2506
          Length = 344

 Score =  107 bits (256), Expect = 1e-21
 Identities = 77/278 (27%), Positives = 131/278 (47%), Gaps = 13/278 (4%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N+++ +PL+ + ++PFRR+ + FGA +   EM      +KG  +E  L    +   +   
Sbjct: 18  NRVFAAPLSGISDVPFRRLSRRFGAGLVVSEMVASGEFVKG-AEEGKLRALRDGPGVHTV 76

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHR----LPALETS 360
           Q+ G +P  + + A+ L +    D ID+N+GCP   +     GS +M         +E +
Sbjct: 77  QLAGRDPIWMEEAARRLADE-GADLIDINMGCPAKKVVGGLSGSALMREPDLAFSIVEAT 135

Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420
           VR A    + P ++KMR G  +D      I  +    G ++ITVHGR+R   Y  ++DW 
Sbjct: 136 VRGAG---ATPVSLKMRLGWCRDSMNAAEIAVRAEAAGVTMITVHGRTRAEFYEGTADWR 192

Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKI 480
            I    + +   PV  NGD+ +  + +     A     VM GRG   +PW    +  +  
Sbjct: 193 AI-CSVKRSVGVPVVANGDL-TEANQLSAILAASGADAVMTGRGMQGRPWFAGLLAGRVT 250

Query: 481 WD-ISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFL 517
            + +S+ D  + +  +    L H+G  T GV   R+ L
Sbjct: 251 MERLSAIDAADFVGGHYEAMLSHYGV-TTGVRHARKHL 287


>UniRef50_A7HK00 Cluster: Dihydrouridine synthase DuS; n=4;
           Thermotogaceae|Rep: Dihydrouridine synthase DuS -
           Fervidobacterium nodosum Rt17-B1
          Length = 322

 Score =  107 bits (256), Expect = 1e-21
 Identities = 69/231 (29%), Positives = 119/231 (51%), Gaps = 15/231 (6%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308
           L+P+  V + PFR++C + GA     EM   +S++  +K       R + +D  G Q+ G
Sbjct: 13  LAPMAGVTDYPFRKLCLQHGAYFAFTEMISAKSVIINVKINEIYFPRQDEKDRVGVQLFG 72

Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL 368
           ++   +++ A ++QE     ++DLN GCP+  + KKG GS ++  L      VR    +L
Sbjct: 73  SDYAELSEAAAIVQEKGL--WVDLNAGCPVSKVIKKGAGSALLKDLGEFRKVVRAMRSVL 130

Query: 369 SIPFTVKMRTGVYQD--KKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426
              FTVK R G  +D  +KI + ++ +        + VHGR+ +  Y+  + W+      
Sbjct: 131 K-RFTVKTRIGWEKDEFEKIYNILLEE----NVDAVFVHGRTAKQMYSGKATWKIYNPGF 185

Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
                 P+Y +GDI++ ED ++         GV++ RG++  PWIF+EI E
Sbjct: 186 -----VPLYISGDIYTKED-IKNAMEQSGATGVIVARGSIGNPWIFSEIGE 230


>UniRef50_O53835 Cluster: Probable tRNA-dihydrouridine synthase;
           n=35; Actinobacteria (class)|Rep: Probable
           tRNA-dihydrouridine synthase - Mycobacterium
           tuberculosis
          Length = 389

 Score =  107 bits (256), Expect = 1e-21
 Identities = 76/247 (30%), Positives = 120/247 (48%), Gaps = 15/247 (6%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADV--TCGEMALCESLLKGLKQEWALVKRHET 298
           I+  + + L+P+  V N+ FR +C++       T   + +CE +      E   V  H T
Sbjct: 18  IELASPVVLAPMAGVTNVAFRALCRQLEQSKVGTVSGLYVCEMVTARALIERHPVTMHMT 77

Query: 299 -----EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGM--M 351
                E     Q+   +P      A+++      D ID+N GCP+  + K+GGG+ +   
Sbjct: 78  TFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHIDMNFGCPVPKVTKRGGGAALPFK 137

Query: 352 HRL--PALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNW-GASLITVHGRS 408
            RL    +  +VR A++   IP TVK R G+  D   TH    +++   GA+ + +H R+
Sbjct: 138 RRLFGQIVAAAVR-ATEGTDIPVTVKFRIGI-DDAHHTHLDAGRIAEAEGAAAVALHART 195

Query: 409 REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIK 468
              RY+ ++DWE I    Q     PV GNGDI+   D + M        GV+IGRG L +
Sbjct: 196 AAQRYSGTADWEQIARLKQHVRTIPVLGNGDIYDAGDALAMMS-TTGCDGVVIGRGCLGR 254

Query: 469 PWIFNEI 475
           PW+F E+
Sbjct: 255 PWLFAEL 261


>UniRef50_Q0FAI7 Cluster: tRNA-dihydrouridine synthase, putative;
           n=1; alpha proteobacterium HTCC2255|Rep:
           tRNA-dihydrouridine synthase, putative - alpha
           proteobacterium HTCC2255
          Length = 324

 Score =  106 bits (255), Expect = 1e-21
 Identities = 68/231 (29%), Positives = 106/231 (45%), Gaps = 5/231 (2%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308
           LSPL  + +LP+R +   FGA +   EM     +++  K   A  +     +    QI G
Sbjct: 13  LSPLAGITDLPYRNLVSSFGAGLVVSEMVASHEIMQKGKDARARAELGFNVEGTSVQIAG 72

Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS-VRCASKL 367
            + + +++ A+L++ N     ID+N+GCP   +     GS +M R P L    +      
Sbjct: 73  RDAFWMSECAKLIEGN-GAKIIDINMGCPAKSVVNGASGSALM-RTPDLALKLIEAVVNA 130

Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427
           + IP T+K R G   +      +       G  +IT+HGR+R   Y   +DW  I    +
Sbjct: 131 VDIPVTLKTRLGWDHNDLNAADLSSSAEKIGIQMITIHGRTRCQFYKGDADWRKIREVKE 190

Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478
           A    PV  NGDI       ++        GVMIGRGA  KPW+ ++I  +
Sbjct: 191 AVN-IPVIANGDIID-TPTAKLAMKQSKADGVMIGRGAQGKPWLLSQIASE 239


>UniRef50_Q8YAB9 Cluster: Lmo0227 protein; n=55; Bacteria|Rep:
           Lmo0227 protein - Listeria monocytogenes
          Length = 331

 Score =  106 bits (254), Expect = 2e-21
 Identities = 67/237 (28%), Positives = 110/237 (46%), Gaps = 3/237 (1%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETED 300
           ++  N++ ++P+  + N  FR   KEFGA + C EM   + +     +   ++   E E 
Sbjct: 7   VEIKNQVVVAPMAGISNSAFRLTVKEFGAGLVCCEMISDKGIAYRNAKTLDMLYIDEKEK 66

Query: 301 LFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS 360
               QI G     + + A+ + ENT  D ID+N+GCP++ I K   G+  +     +   
Sbjct: 67  PLSLQIFGGEKETLVEAAKFVAENTTADIIDINMGCPVNKIIKCEAGAKWLLDPNKVYDM 126

Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420
           V      +  P TVKMR G  ++              GA+ + +HGR+R   Y  S++W+
Sbjct: 127 VAAVVDAVDKPVTVKMRIGWDEEHVFAIENALAAERAGAAAVAMHGRTRVQMYEGSANWD 186

Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPW-IFNEIK 476
            +    +     P   NGD+ + ED   + +      GVMIGR AL  PW I+  +K
Sbjct: 187 VLRD-VKRELKIPFMANGDVRTPEDAKRILE-HTGADGVMIGRAALGNPWMIYRTVK 241


>UniRef50_Q14SX5 Cluster: Putative dihydrouridine synthase; n=1;
           Ruminococcus flavefaciens|Rep: Putative dihydrouridine
           synthase - Ruminococcus flavefaciens
          Length = 332

 Score =  106 bits (254), Expect = 2e-21
 Identities = 71/229 (31%), Positives = 112/229 (48%), Gaps = 6/229 (2%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308
           L+P+  V +  +R +CK +GA     EM   + +    ++   L    E E     Q+ G
Sbjct: 18  LAPMAGVADRAYRLMCKRYGAAYVVSEMVSAKGICYSDRKTAELCTVTEEERPMAVQLFG 77

Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL 368
           + P  + +  +++ +    D ID+N+GCP+  +   G GS +M + PAL  ++  A+   
Sbjct: 78  SEPDFMAEAVKIVLDYRP-DIIDINMGCPVPKVVGTGAGSALM-KDPALAAAITEAAVKA 135

Query: 369 S--IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426
           +   P TVK+R+G   D      +   +   G + I VHGR+R+  Y+  SD   I+   
Sbjct: 136 AGDTPVTVKIRSGWSSDSINAPEMARALEASGTAAIAVHGRTRDMFYSGQSDMNVIKAVK 195

Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
           +A +  PV GNGDI   E   EM         VMIGRG+   P+IF EI
Sbjct: 196 EAVS-VPVIGNGDITDAESCAEMYG-RTGCDLVMIGRGSYGNPFIFREI 242


>UniRef50_Q9RRP8 Cluster: NifR3 protein; n=2; Deinococcus|Rep: NifR3
           protein - Deinococcus radiodurans
          Length = 406

 Score =  105 bits (252), Expect = 3e-21
 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 6/228 (2%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQE-WALVKRHETEDLFGAQIC 307
           L+P+    + P R++  E GA  T  EM     L+ G +QE  +L + +  E     Q+ 
Sbjct: 96  LAPMAGYSDAPMRQLAAEQGALWTVSEMISARGLVLGSEQESLSLGRPYPGEQGRAVQLF 155

Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367
           G +P ++       +       IDLN+GCP+  +  KGG   +     A E  VR   + 
Sbjct: 156 GADPDVLADAVGKAEAWFAPAAIDLNLGCPVPKVRGKGGACLLQTPEVAYEL-VRAMRQA 214

Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427
             +  + K+R G  +++ +   I   +   GA+++TVHGR+   RYT ++DW+ I   AQ
Sbjct: 215 TGLDVSAKIRLGWDENRSVE--IAQGLEAAGAAVVTVHGRTSAQRYTGNADWDAIGRVAQ 272

Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
           A    PV G+GD+ S     E R     V  VMIGRGA+  PW+F  I
Sbjct: 273 AVR-IPVIGSGDVLSPVQARE-RMQQSGVAAVMIGRGAVGNPWMFRAI 318


>UniRef50_Q3AZ67 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=20; Cyanobacteria|Rep: Dihydrouridine synthase
           TIM-barrel protein nifR3 - Synechococcus sp. (strain
           CC9902)
          Length = 356

 Score =  105 bits (252), Expect = 3e-21
 Identities = 75/235 (31%), Positives = 115/235 (48%), Gaps = 7/235 (2%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGAD-VTCGEMALCESLLKGLKQEWALVKRHETEDLF 302
           ++++  SPL  V +  FR + + +  D +   EM    SL  G      +      E   
Sbjct: 36  HSRVLQSPLAGVTDKIFRGLVRRWSRDSLLFTEMVNATSLELG-HGYGKMDDLKAEEGPI 94

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV- 361
             Q+  + P+ +   A+  ++      ID+N+GCP+  I KKGGGSG++ R P L T + 
Sbjct: 95  AVQLFDHRPHAMAHAARRAEQAGAF-LIDINMGCPVRKIAKKGGGSGLI-RDPNLATQIL 152

Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
                 +SIP TVK R G         T   ++ N GA ++T+HGR+RE  +   ++W  
Sbjct: 153 EAVVDAVSIPVTVKTRLGWCGSSSDPITWCRQLQNAGAQMLTLHGRTREQGFKGQANWNA 212

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
           I    QA T  PV  NGDI S  D +   +I     GVM+GRG +  PW+  +I+
Sbjct: 213 IAEVKQALT-IPVIANGDINSPTDALRCLEIT-GADGVMVGRGTMGSPWLVGQIE 265


>UniRef50_Q5FTP7 Cluster: Nitrogen assimilation regulatory protein
           NifR3; n=3; Acetobacteraceae|Rep: Nitrogen assimilation
           regulatory protein NifR3 - Gluconobacter oxydans
           (Gluconobacter suboxydans)
          Length = 371

 Score =  104 bits (250), Expect = 6e-21
 Identities = 72/280 (25%), Positives = 133/280 (47%), Gaps = 12/280 (4%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308
           L+PL+ V +LPFR++ ++ GA +   EM    ++++  +    + +  E       Q+ G
Sbjct: 39  LAPLSGVTDLPFRQLARDLGAGLVVSEMIASWAMIRENENTMRMARMAERGPN-AVQLAG 97

Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLI-YKKGGGSGMMHRLPALETSVRCASKL 367
            +P  + + A++  +    + ID+N GCP+  +   +  GS +M         +   ++ 
Sbjct: 98  CDPKAMAQAAKISVDGGA-NLIDINFGCPVKKVAIGQMAGSALMRDEVLAGKLLEATARA 156

Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427
           +++P T+KMR G   +      +       G  L+TVHGR+R+  Y  ++DW +++T   
Sbjct: 157 VNVPVTLKMRMGWDHNSLNAPRLAKIAEESGIRLVTVHGRTRQMFYNGTADWRFVKTVKD 216

Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE-----QKIWD 482
           A +  PV  NGDI +  D  E         GVMIGRG   +PW   ++ +     + + D
Sbjct: 217 AVS-LPVIVNGDINTIRDAREALH-QSQADGVMIGRGCYGRPWFTAQVAQSLRTGEDVPD 274

Query: 483 ISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLS 522
                  EI  ++    L+H+G +  G+   R+  + W S
Sbjct: 275 PDLATEKEIALRHYRMMLDHFG-ERPGLRLARKH-VSWYS 312


>UniRef50_Q2RTR9 Cluster: Dihydrouridine synthase TIM-barrel protein
           nifR3; n=1; Rhodospirillum rubrum ATCC 11170|Rep:
           Dihydrouridine synthase TIM-barrel protein nifR3 -
           Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
          Length = 362

 Score =  104 bits (250), Expect = 6e-21
 Identities = 66/229 (28%), Positives = 109/229 (47%), Gaps = 7/229 (3%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK----GLKQEWALVKRHETEDLF 302
           + L+P+  V + PFRR+  ++G  ++  EM     LL+    G+               F
Sbjct: 14  IMLAPMAGVTDSPFRRLAHDYGCPLSWTEMVASRELLRERARGVDPRLGGGAEAGRAGPF 73

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             Q+ G +P I+ + A+ + E    + ID+N+GCP+  +    GGS +M  LP     + 
Sbjct: 74  AVQLAGCDPLIMAEAARRV-EGAGAELIDINMGCPVRKVVGGLGGSALMRDLPLAARILE 132

Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
                +++P ++KMR G     +    +     + G S +TVHGR+R   Y   +DW  I
Sbjct: 133 AVVGAVTLPVSLKMRLGWDDASRNAVELARLAESAGISRLTVHGRTRAQMYDGRADWPAI 192

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWI 471
               +A +  PV  NGD+ +  +  E+  +     GVMIGR AL  PW+
Sbjct: 193 GLVKRAVS-LPVIANGDVTNLSEAREILAVT-GADGVMIGRAALGAPWL 239


>UniRef50_Q55724 Cluster: Probable tRNA-dihydrouridine synthase 1;
           n=15; Cyanobacteria|Rep: Probable tRNA-dihydrouridine
           synthase 1 - Synechocystis sp. (strain PCC 6803)
          Length = 355

 Score =  104 bits (250), Expect = 6e-21
 Identities = 68/243 (27%), Positives = 120/243 (49%), Gaps = 5/243 (2%)

Query: 235 PRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVK 294
           P +  ++  ++++  SPL+ V +L FRR+ + +          +  + +  L+    +++
Sbjct: 32  PLQIGSLTLHSRVLQSPLSGVTDLVFRRLVRRYAPQAMLYTEMVSATEIHHLRTLPQVME 91

Query: 295 RHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRL 354
               E+    Q+    P  + + AQ          +D+N+GCP++ I KKGGGS ++ + 
Sbjct: 92  IDPRENPISIQLFDCRPDFMAEAAQKAVAQGAQS-VDINMGCPVNKITKKGGGSSLLRQP 150

Query: 355 PALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT-IVPKMSNWGASLITVHGRSREARY 413
              E  V+     + +P TVK R G + D +I       ++ + GA ++T+HGR+R   Y
Sbjct: 151 AVAEAIVKTVVAAVDVPVTVKTRLG-WDDGEINIVEFAQRLQDAGAQMLTLHGRTRAQGY 209

Query: 414 TKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473
              + W++I    QA T  PV  NGDIFS E  +   +      GVM  RG+L  P++  
Sbjct: 210 NGRARWQWIAKVKQALT-IPVIANGDIFSVEAAIACLE-ETGADGVMCSRGSLGYPFLVG 267

Query: 474 EIK 476
           EI+
Sbjct: 268 EIE 270


>UniRef50_O83945 Cluster: Probable tRNA-dihydrouridine synthase;
           n=2; Treponema|Rep: Probable tRNA-dihydrouridine
           synthase - Treponema pallidum
          Length = 340

 Score =  104 bits (249), Expect = 8e-21
 Identities = 66/240 (27%), Positives = 120/240 (50%), Gaps = 11/240 (4%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           ++ +P+    +  FR I  E+ A  T  EM   E++++       L++R   E  +  QI
Sbjct: 21  VFFAPVAGYSDSAFRSIAIEWEASFTYTEMVSSEAMVRDSLNTKRLIRRASNETHYAIQI 80

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
            G+NP ++ + A+L+ ++ +   ID+N GCP+  I K G G+ +      L   V+  + 
Sbjct: 81  FGSNPAVMAETAKLIVDSAQPSCIDINAGCPMPKITKTGAGAALTREPTRLYEVVKAVAD 140

Query: 367 LL-----SIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITVHGRSREARYTKSSDWE 420
            +      IP TVK+R G +++  +T     + + + GA  + +H R+    Y   ++W+
Sbjct: 141 AVYAQDARIPVTVKIRAG-WEEAHLTWKEAARAAVDAGAQALALHPRTCAQCYAGEANWD 199

Query: 421 YIE---TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
            I     CA+     PV+G+GD+ + ED   M +      GVM  RGA+  P+IF + ++
Sbjct: 200 IIADLVQCARGWGEVPVFGSGDLHAPEDARAMLE-HTACAGVMFARGAMGNPFIFRQTRQ 258


>UniRef50_Q00XL7 Cluster: TRNA-dihydrouridine synthase; n=1;
           Ostreococcus tauri|Rep: TRNA-dihydrouridine synthase -
           Ostreococcus tauri
          Length = 295

 Score =  103 bits (247), Expect = 1e-20
 Identities = 51/118 (43%), Positives = 73/118 (61%), Gaps = 3/118 (2%)

Query: 371 PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAAT 430
           P TVK+R G+      T  I  ++ N GA+ I VHGR++E RYTKS+D++ I        
Sbjct: 36  PLTVKIRLGIESSSPATK-IAERLENAGAAAIIVHGRTKEQRYTKSADYDVIRQIVSERA 94

Query: 431 PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDR 488
             PV GNGD+ ++ D  + R       G+M+GRGALIKPWIF E +E+K W+ +++DR
Sbjct: 95  -IPVIGNGDVLTWYD-AQQRLDYSGCAGIMVGRGALIKPWIFKEFREKKEWEPTAEDR 150


>UniRef50_Q090Q9 Cluster: TRNA-dihydrouridine synthase B; n=2;
           Cystobacterineae|Rep: TRNA-dihydrouridine synthase B -
           Stigmatella aurantiaca DW4/3-1
          Length = 369

 Score =  102 bits (245), Expect = 2e-20
 Identities = 65/232 (28%), Positives = 112/232 (48%), Gaps = 3/232 (1%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVK-RHETEDLFG 303
           N   L+P+  V   PFR I  ++GA +   E+   + L++  ++    ++   E E  + 
Sbjct: 43  NPYILAPMAGVSERPFRVIAFKWGAALCPTELVSAQGLMRANQRTLKYLRFSPEVERPYS 102

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
            QI G  P  + + A L+ +      ID+N+GCP+  + K G GS +M         V+ 
Sbjct: 103 LQIFGGEPEAMAQAA-LVGKAHGAQIIDINMGCPVKKVTKNGAGSALMCEPLRAARIVQA 161

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
            ++   +P T K+R+G     +    +  ++ + G + + +H R+R+  Y+  +DW  I 
Sbjct: 162 IAEATGLPVTCKIRSGWDAHHRNYLQMAGELFSAGCAALAIHPRTRDQGYSGFADWSVIA 221

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
              +      + GNGD+ +  D   MR+       VMIGRGAL  PWIF E+
Sbjct: 222 DLKRHFPDRTLIGNGDVKTPADARRMRE-TTGCDFVMIGRGALGNPWIFREL 272


>UniRef50_A7BE39 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 411

 Score =  102 bits (245), Expect = 2e-20
 Identities = 61/210 (29%), Positives = 99/210 (47%), Gaps = 11/210 (5%)

Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334
           EM    +L++  ++   +V+    E +   Q+ G NP ++ K A +L E    D IDLN 
Sbjct: 74  EMVTSRALVEENERTLEMVRPDPAERVRSLQLYGVNPAVMAKAATMLVERDLTDHIDLNF 133

Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL---------SIPFTVKMRTGVYQDKK 385
           GCP+  + KKGGG+ +  +       V    +            IP TVK+R G+  + +
Sbjct: 134 GCPVPKVTKKGGGAALPWKRDLFSDLVGAVVRACDEAGERAGREIPVTVKIRIGIDSEHE 193

Query: 386 ITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYED 445
                       GA+ +T+H R++   Y   + W+ I    +     PV+GNGD+F   D
Sbjct: 194 TATDAALNAQKLGAAALTLHARTQNQHYAGHAHWDEIAR-LKDLLDIPVFGNGDVFEAAD 252

Query: 446 YVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
            + M +      G+ +GRGA  +PWIF +I
Sbjct: 253 ALAMLE-QTGCDGISVGRGAQGRPWIFRDI 281


>UniRef50_Q607L4 Cluster: TIM-barrel protein, yjbN family; n=10;
           Proteobacteria|Rep: TIM-barrel protein, yjbN family -
           Methylococcus capsulatus
          Length = 327

 Score =  102 bits (244), Expect = 3e-20
 Identities = 68/233 (29%), Positives = 113/233 (48%), Gaps = 5/233 (2%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE-DLF 302
           ++ + L+P+  V +LPFRR+C++FGA +   EM      L+  ++   L + H  E    
Sbjct: 9   SSPVILAPMAGVTDLPFRRLCRQFGAGLAVSEMISASPALQATRKS-RLRQDHRGEPGPI 67

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             QI G +P  + + A+   +    D ID+N+GCP   +     GS ++     +   + 
Sbjct: 68  SVQIVGADPREMAEAARRTVD-LGADIIDINMGCPAKKVCNVAAGSALLRDEKLVANILE 126

Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
              + + +P T+K+RTG     +   +I     + G   +TVHGR+R   +  ++++  I
Sbjct: 127 AVVQAVPVPVTLKIRTGWDSASRNAVSIGKIAESAGIRALTVHGRTRACGFAGAAEYSTI 186

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
            T  + A   PV  NGDI S     E    +     VMIGRGA  +PW+  EI
Sbjct: 187 -TEVKKAIGIPVIANGDIDS-PGKAEAVLRSTGADAVMIGRGAWGRPWLLREI 237


>UniRef50_A7CWF1 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Opitutaceae bacterium TAV2|Rep: Putative TIM-barrel
           protein, nifR3 family - Opitutaceae bacterium TAV2
          Length = 389

 Score =  101 bits (241), Expect = 7e-20
 Identities = 74/234 (31%), Positives = 113/234 (48%), Gaps = 9/234 (3%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLKGLKQEWALVKRHETEDLF 302
           ++ L+LSPL    NLP R   +E G       ++    SL++  K    LV+    +   
Sbjct: 9   SSNLFLSPLAGYTNLPMRLTVRELGGLGWATTDLVNARSLIERSKGAMKLVETAPGDQPL 68

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             Q+ G+ P  +   A + +E      +D+N+GCP+  +   GGG+ MM  L      VR
Sbjct: 69  AIQLFGSVPEEMRDAAVICKE-LGAQSVDVNMGCPVKKVVGIGGGAAMMTELNKTAALVR 127

Query: 363 CASKLLS--IPFTVKMRTGVYQDKKITHTIVPK-MSNWGASLITVHGRSREARYTKSSDW 419
              + +   IP T KMR G + D  IT   + + +++ G + I VHGR+R   ++ + + 
Sbjct: 128 GMVEAVGNKIPVTAKMRLG-WDDANITAPDLARVLADVGVAAIFVHGRTRAQGFSGTVNL 186

Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIF 472
             I    +A    PV GNGD+ + E    M  IA T   GV +GRGA   PWIF
Sbjct: 187 AGIRAVVEAVPGLPVIGNGDVTTPESARHM--IAETGCAGVSVGRGAFYDPWIF 238


>UniRef50_Q5ZRM0 Cluster: Nitrogen regulation protein; n=4;
           Legionella pneumophila|Rep: Nitrogen regulation protein
           - Legionella pneumophila subsp. pneumophila (strain
           Philadelphia 1 /ATCC 33152 / DSM 7513)
          Length = 329

 Score =  100 bits (239), Expect = 1e-19
 Identities = 72/251 (28%), Positives = 117/251 (46%), Gaps = 13/251 (5%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTC-GEMALCESLLKGLKQEWALVKRHETEDLFG 303
           ++L   PL      PFR +   +     C  EM     +L     +   + R  TE    
Sbjct: 19  HRLIQGPLAGYSCAPFRDLFNIYTPPAYCVSEMCSAIDILHKHSSQSRYIYRAPTEKFLA 78

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM---HRLPALETS 360
            QI GN P+++ + A  LQ +   D ID+N GCP   I KKG GS ++    +L A+ + 
Sbjct: 79  YQISGNEPHVLAEAAAKLQ-SLGADLIDINCGCPKSKIRKKGAGSALLEDPQKLIAIISR 137

Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420
           VR A   +SIP T+K+R    Q+ +   T+  ++ + GA  + VHGR     Y    +W+
Sbjct: 138 VRAA---ISIPLTIKIR---IQNNEKDLTLAKQIEDAGAHALIVHGRRWTEDYDIPCNWQ 191

Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKI 480
            I     A    PV  NGDI +     +  +I+    G MI R    KPW++ ++   + 
Sbjct: 192 QIANIKNAVN-IPVIVNGDINNIFSLRKALEIS-ACDGFMISRAGTGKPWLYRDLLNLET 249

Query: 481 WDISSKDRFEI 491
            D++  ++ ++
Sbjct: 250 NDVAFDEKLKL 260


>UniRef50_A6DPY9 Cluster: Putative uncharacterized protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Putative
           uncharacterized protein - Lentisphaera araneosa HTCC2155
          Length = 330

 Score =   99 bits (238), Expect = 2e-19
 Identities = 80/233 (34%), Positives = 117/233 (50%), Gaps = 16/233 (6%)

Query: 246 KLYLSPLTTVGNLPFR-RICKEFGADVTCGEMALCES---LLKGLKQEWALVKRHETEDL 301
           KL L+P+  V +   R +I +  G D+ C E     S    ++ LK++  +VK  +    
Sbjct: 8   KLSLAPMEGVTHPLMRHQIAQHGGLDLLCTEFIRISSHKPSMRSLKKQ--IVKSGDIP-- 63

Query: 302 FGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361
              QI GNN  ++ + A+L+ +    D +D+N+GCP     K G GS M+ + P L   V
Sbjct: 64  LSVQIMGNNAELMAESAKLVVD-CGADAVDVNMGCPTKRAVKGGVGSAML-KDPKLCYQV 121

Query: 362 RCASKLLSIP--FTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419
             AS    +P   + K+R G + +K+    I+  + + GA  + VH R R   Y   SDW
Sbjct: 122 -LASMREQVPCALSAKIRAG-FDNKEGVFEILQAIVDSGADYLAVHPRRRVDHYEGHSDW 179

Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
             I    + + P PV GNGD+ +  D V M K      GVMIGRGAL  PWIF
Sbjct: 180 RIISALKEKS-PIPVIGNGDVRTAADAVRMFK-ETQCDGVMIGRGALSNPWIF 230


>UniRef50_Q8RFK3 Cluster: Nitrogen regulation protein NIFR3; n=3;
           Fusobacterium nucleatum|Rep: Nitrogen regulation protein
           NIFR3 - Fusobacterium nucleatum subsp. nucleatum
          Length = 307

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 70/234 (29%), Positives = 116/234 (49%), Gaps = 8/234 (3%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305
           K+Y++P+  V +  FR I ++F  D+   EM    +L   +  +  + K  +  +    Q
Sbjct: 3   KIYIAPIAGVTDYTFRGILEDFKPDLIFTEMVSVNAL--SVLNDKTISKILKLREGNAVQ 60

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
           I G +   I    + + EN  +  I+LN GCP+  I   G G+ ++     ++  +    
Sbjct: 61  IFGEDIEKIKASVKYI-ENLGVKHINLNCGCPMKKIVNCGYGAALVKEPEKIKKILSEIK 119

Query: 366 KLLS--IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
            +L+     +VK+R G Y++ +    I       G   ITVHGR+RE  Y+  +DW+YI+
Sbjct: 120 SVLNNDTKLSVKIRIG-YKEPENYIQIGKIAEELGCDHITVHGRTREQLYSGKADWKYIK 178

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
                 +  PV GNGDIF+ ED +E +     V GVM+ RG    PW+  +I+E
Sbjct: 179 EVKDNIS-IPVIGNGDIFTGEDALE-KIFYSNVDGVMLARGIFGNPWLIRDIRE 230


>UniRef50_Q0C0N1 Cluster: Putative tRNA-dihydrouridine synthase;
           n=1; Hyphomonas neptunium ATCC 15444|Rep: Putative
           tRNA-dihydrouridine synthase - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 345

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 71/234 (30%), Positives = 111/234 (47%), Gaps = 10/234 (4%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305
           +++L+P++   + P RR    FGA     EM   E L K          RHE    +  Q
Sbjct: 22  RVWLAPMSGATDAPMRRQAVHFGAPAVVSEMVAGEMLAKARADVVRRTCRHEGAGYWIVQ 81

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
           +    P  +   A L+ E   +D ID+N+GCP   +     GS +M  LP     +  A 
Sbjct: 82  LAARRPEDMLAGAVLMAE-AGVDVIDINMGCPSKQVTGGQSGSALMRDLPLAGEIIDAAL 140

Query: 366 K-LLSIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITVHGRSREARYTKSSDWEYIE 423
           +     P T+KMR G + D+ +    +  M+ + G  ++TVHGR+R   YT  ++W  + 
Sbjct: 141 QGAAGRPVTLKMRLG-WDDENLNAPELAVMAQDRGVQMLTVHGRTRCQFYTGGANWAAVR 199

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRK-IAPT-VKGVMIGRGALIKPWIFNEI 475
               A +  PV  NGDI    D    R+ +A +   GVM+GR A+ +PW+  E+
Sbjct: 200 ATVDAVS-LPVIVNGDI---SDTASAREALAQSGAYGVMLGRAAMGRPWLVGEV 249


>UniRef50_Q5CSA9 Cluster: Dus1p, tRNA dihydrouridine synthase; n=2;
           Cryptosporidium|Rep: Dus1p, tRNA dihydrouridine synthase
           - Cryptosporidium parvum Iowa II
          Length = 409

 Score = 98.7 bits (235), Expect = 4e-19
 Identities = 73/275 (26%), Positives = 132/275 (48%), Gaps = 13/275 (4%)

Query: 230 LIKLLPRER-KTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEM--ALCESLLKGL 286
           + KL P E  K +  + K  L+P+     L FR ICK++G D+    M  +   S L+G 
Sbjct: 3   MTKLSPWENWKNVLKSPKTVLAPMVDGSELAFRLICKKYGCDLGYSPMYHSGLFSKLQGY 62

Query: 287 KQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG 346
           ++     +  E +D    Q CGN+P  + K ++ + +  +   ID+N GCP ++  +   
Sbjct: 63  RE--TNFQTCEEDDPMIVQFCGNDPETLVKASKFIDDKVK--GIDINFGCPQNIAKRGNY 118

Query: 347 GSGMMHRLPALETSVRCASKL-LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVH 405
           G+ ++     +E  +   S+  L  P + K+R   + D + T  ++ ++ + GA +I VH
Sbjct: 119 GAFLLSNPDLMERIISTLSESDLKCPVSCKIRILDHHDLQPTINLIKRLESAGACMIAVH 178

Query: 406 GRSREAR--YTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGR 463
           GR+  +R   T  ++WE ++   ++    P   NG I +YED  +          VM   
Sbjct: 179 GRTMTSRGVLTGPANWEALK-ILKSRCSIPFIANGGISNYEDIQKCLNYT-GADAVMSAE 236

Query: 464 GALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNY 498
           G L  PW+F   K  +  + +   +F+I  +Y +Y
Sbjct: 237 GILENPWLFQGFKTPEAIN-NKPSQFQIALEYLDY 270


>UniRef50_Q08111 Cluster: Probable tRNA-dihydrouridine synthase;
           n=21; Alphaproteobacteria|Rep: Probable
           tRNA-dihydrouridine synthase - Rhodobacter capsulatus
           (Rhodopseudomonas capsulata)
          Length = 324

 Score = 98.3 bits (234), Expect = 5e-19
 Identities = 66/230 (28%), Positives = 103/230 (44%), Gaps = 8/230 (3%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDL-FGAQIC 307
           L+P+  + +LPFRR+   FGA +   EM     +L       A  +   T  L    Q+ 
Sbjct: 16  LAPMAGITDLPFRRMVARFGAGLVVSEMVASGEMLTAKPSVRAKAQAELTAGLPTSVQLA 75

Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367
           G     + + A+++ +    + ID+N+GCP   +     G+ +M         +      
Sbjct: 76  GREAAPMAEAAKIVAD-MGAEIIDINMGCPAKKVTGGLSGAALMRNPDHALRLIEAVVGA 134

Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427
           + +P T+KMR G  +D+     I  +    G  +I +HGR+R   YT ++DW  I    +
Sbjct: 135 VDLPVTLKMRLGWDEDQLNAAEIAARAEAAGVKMIVIHGRTRMQFYTGAADWRAI-AAVR 193

Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPT--VKGVMIGRGALIKPWIFNEI 475
           AA   PV  NGDI    D    R+        GVM+GRGA   PW   +I
Sbjct: 194 AAVSVPVVANGDI---TDAASARRALDQSGAAGVMVGRGAQGAPWRLAQI 240


>UniRef50_Q89LQ7 Cluster: Nitrogen regulation protein; n=22;
           Alphaproteobacteria|Rep: Nitrogen regulation protein -
           Bradyrhizobium japonicum
          Length = 371

 Score = 97.9 bits (233), Expect = 7e-19
 Identities = 68/231 (29%), Positives = 109/231 (47%), Gaps = 8/231 (3%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDL--FGA 304
           ++L+P++ V + P RR+  E GA +   EM   + L  G +       R E   +     
Sbjct: 50  VFLAPMSGVTDSPVRRLVAELGAGLVVSEMTASDELANGHRMSRL---RCEATGIGPHVV 106

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G   + + + A++  E    D ID+N+GCP   +     GS +M  L      +   
Sbjct: 107 QLAGCEAHWMAEGARIA-EAEGADIIDINMGCPARHVTGGQSGSALMRDLDHAVGLIDAT 165

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
              + +P T+KMR G     +    +  +    G  L+TVHGR+R   Y   +DW+ I T
Sbjct: 166 IAAVKVPVTLKMRLGWDDRSRNAPELARRAEAAGIKLVTVHGRTRCQFYKGEADWDAIRT 225

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
             +A +  P+  NGDI SYE  +   + +     VMIGRGA  +PW+  +I
Sbjct: 226 VREAIS-IPLIVNGDITSYEKALAALE-SSGADAVMIGRGAQGQPWLPGQI 274


>UniRef50_Q9A7I4 Cluster: Nitrogen regulation protein Nifr3; n=2;
           Caulobacter|Rep: Nitrogen regulation protein Nifr3 -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 315

 Score = 97.5 bits (232), Expect = 9e-19
 Identities = 72/226 (31%), Positives = 96/226 (42%), Gaps = 4/226 (1%)

Query: 252 LTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNP 311
           +T V +LPFR      GA     EM       KG           E   L   Q+ G + 
Sbjct: 1   MTGVSDLPFRETASALGAPYVATEMVASAEFAKGRPDVVRRAAVGEGLPLTVIQLVGRDV 60

Query: 312 YIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRCASKLLSI 370
             + + A++ QE    + IDLN GCP   +      GS +M      E  V  A + + +
Sbjct: 61  DFMAQGARMAQE-AGAEIIDLNFGCPAKEVAAGAACGSALMREPDLAEALVAAAVEAVDV 119

Query: 371 PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAAT 430
           P TVKMR G   D      I  +    GA  +TVHGR+R   Y   +DW  +    QA +
Sbjct: 120 PVTVKMRLGWDIDCLNAPDIARRAEAAGAKAVTVHGRTRNQFYKGVADWTAVAAVKQAVS 179

Query: 431 PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
             PV  NGDI   E   +  +      GVMIGRG   +PWI   I+
Sbjct: 180 -VPVLVNGDIVDGETARQALE-QSGADGVMIGRGVYGRPWIAGAIE 223


>UniRef50_A7DPL5 Cluster: Putative TIM-barrel protein, nifR3 family;
           n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Putative TIM-barrel protein, nifR3 family - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 320

 Score = 97.5 bits (232), Expect = 9e-19
 Identities = 72/265 (27%), Positives = 126/265 (47%), Gaps = 16/265 (6%)

Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGE-------MALCESLLKGLKQEWALVKR 295
           ++++ +L+P+  V +   R  CK+ GA +   E       +A  E L + +K     ++ 
Sbjct: 5   FSSRAFLAPMAGVSDPALRLQCKKMGAGLVVTEFTSIHSIIAKEEQLKENMKTIQEFIEF 64

Query: 296 HETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLP 355
            E E     Q+ G++ Y + K A +++     D ID N+GCP   I ++  G  ++  + 
Sbjct: 65  SEQERPISVQLFGSDLYALEKAATIVEPY--FDIIDYNMGCPAPHITQQMAGGALLQEVN 122

Query: 356 ALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITVHGRSREARYT 414
             +         +  P T+K+R+GV    K     + +++ + G  +IT H R+    Y+
Sbjct: 123 LTQQIFETLVNAVKKPVTLKIRSGVTDASKFLFRDIAEIAEDQGIQMITFHPRTVSQGYS 182

Query: 415 KSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
            S+DW+ I+   + +   PV GNGDI + ED  +M         VMIGRGA+  P++F +
Sbjct: 183 GSADWKLIKELKEISN-IPVVGNGDITTPED-AKMMLDETGCDYVMIGRGAMGNPFLFEQ 240

Query: 475 I----KEQKIWDISSKDRFEILKKY 495
           I    K     + S KDR +    Y
Sbjct: 241 INDYLKTGSYKEYSFKDRLDSFFDY 265


>UniRef50_A0EG06 Cluster: Chromosome undetermined scaffold_94, whole
           genome shotgun sequence; n=4; Intramacronucleata|Rep:
           Chromosome undetermined scaffold_94, whole genome
           shotgun sequence - Paramecium tetraurelia
          Length = 360

 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 68/237 (28%), Positives = 118/237 (49%), Gaps = 13/237 (5%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLL--KGLKQEWALVKRHETEDLFG 303
           K   +P+     L FR + +++G  +    M     +   K  K E+      E   LF 
Sbjct: 19  KFICAPMVDQSELAFRMLTRKYGTTLAYTPMLHSRIMTESKSYKDEF-FTTCPEDRPLF- 76

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
           AQ+CG++P ++ K A ++Q+  + D ID+N+GCP  +  K   G+ ++ +   + T V+ 
Sbjct: 77  AQLCGHDPQVLIKAALMIQD--QCDAIDINLGCPQGIARKGLYGAYLLEKREQVLTIVKE 134

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEY 421
             + +++P T K+R  +++D+K T  +   +   G S++TVHGR++E    +    DW  
Sbjct: 135 LKQNINVPVTCKIR--MFKDRKRTLDLTKDIQEAGCSILTVHGRTKEQNKDFVGQCDWTI 192

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN-EIKE 477
           I    Q     PV+ NG I+++ D VE       V  VM     L  P +F+ EIK+
Sbjct: 193 IAEIKQ-ILQIPVFANGGIYTWSD-VERCLQETKVDAVMSSEALLENPALFSGEIKD 247


>UniRef50_Q8ZAX7 Cluster: tRNA-dihydrouridine synthase B; n=214;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase B -
           Yersinia pestis
          Length = 321

 Score = 94.7 bits (225), Expect = 6e-18
 Identities = 61/234 (26%), Positives = 106/234 (45%), Gaps = 7/234 (2%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N L  +P+  + + PFR +C   GA +   EM      +    +    +   +   +   
Sbjct: 10  NCLIAAPMAGITDRPFRALCHGMGAGMAVSEMLSSNPEVWRTDKSRLRMVHVDEPGIRNV 69

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           QI GN+P  +   A++    +    ID+N+GCP   + +K  GS ++     ++  +   
Sbjct: 70  QIAGNDPDEMAAAARI-NVASGAQIIDINMGCPAKKVNRKLAGSALLQHPDLVKQILSAV 128

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
              + +P T+K+RTG   + +    I     N G   +T+HGR+R   +   ++++ I  
Sbjct: 129 VNAVDVPVTLKIRTGWSPEHRNCIEIAQLAENCGIQALTIHGRTRSCLFNGEAEYDSIRA 188

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIA--PTVKGVMIGRGALIKPWIFNEIK 476
             Q  +  PV  NGDI    D  + R +        +MIGR A  +PWIF EI+
Sbjct: 189 VKQTVS-IPVIANGDI---TDPHKARAVLDYTGADALMIGRAAQGRPWIFREIQ 238


>UniRef50_Q54ES7 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 344

 Score = 92.3 bits (219), Expect = 3e-17
 Identities = 70/253 (27%), Positives = 117/253 (46%), Gaps = 11/253 (4%)

Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309
           +P+     LPFR + K++G D+T   M +     +      +    ++ ++    Q   N
Sbjct: 60  APMVRFSRLPFRMLVKKWGCDITYTPMIMAAEFNRSEAARDSDFTINKLDEPLIVQFGVN 119

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369
           N   +   A+ +++  +   ID+N GCP   + K+G G+ ++     +   V+  +  + 
Sbjct: 120 NAEELVSAAEKVKDYCQ--GIDINCGCPQRWVMKEGFGANLLLHPERIYDMVKQINNRVP 177

Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429
           IP ++K+R  V  D K T  +  +    G S ITVHGR+   + +   D++ I+      
Sbjct: 178 IPISIKIR--VQSDLKDTIELAKRAERIGVSWITVHGRTSAMKSSHPVDYDAIKLVKDNV 235

Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRF 489
           T  PV+ NGD+F+     E+R+    V GVM  RG L  P +F    +  I  I  KD  
Sbjct: 236 T-LPVFANGDVFTLSQSNEIRE-KTGVNGVMSARGLLTNPALFQGYDKTPIECI--KDFI 291

Query: 490 EILKKYSNYGLEH 502
            I   YS YG  H
Sbjct: 292 NI---YSEYGGLH 301


>UniRef50_Q1QZQ6 Cluster: Dihydrouridine synthase, DuS; n=1;
           Chromohalobacter salexigens DSM 3043|Rep: Dihydrouridine
           synthase, DuS - Chromohalobacter salexigens (strain DSM
           3043 / ATCC BAA-138 / NCIMB13768)
          Length = 340

 Score = 91.9 bits (218), Expect = 4e-17
 Identities = 51/150 (34%), Positives = 78/150 (52%), Gaps = 6/150 (4%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS---IPFTVKMRTGVYQDKKI 386
           +DLN GCP   + +  GG+ ++ +   + T VR  ++ L+   I  T K+R G + DK +
Sbjct: 99  VDLNFGCPAKTVNRHDGGASLLRQPERVHTVVRAVAEALAPLGIAVTAKIRLG-FDDKHV 157

Query: 387 THTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDY 446
                    + GA+ + VH R+R   Y   + WE+I    QA    PV  NGDI++ EDY
Sbjct: 158 ALACAEAAESGGAAHLVVHARTRREGYRPPAHWEWIGR-IQARLSIPVIANGDIWTLEDY 216

Query: 447 VEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
            + R ++     VM+GRG L  PW+   IK
Sbjct: 217 WKARTLSGCA-DVMLGRGMLADPWLARRIK 245


>UniRef50_Q8SUV4 Cluster: Putative uncharacterized protein
           ECU07_1610; n=1; Encephalitozoon cuniculi|Rep: Putative
           uncharacterized protein ECU07_1610 - Encephalitozoon
           cuniculi
          Length = 341

 Score = 91.9 bits (218), Expect = 4e-17
 Identities = 69/233 (29%), Positives = 109/233 (46%), Gaps = 16/233 (6%)

Query: 248 YLSPLTTVGNLP--FRRICKEFGADVTCGEMALCESLLKG----LKQEWALVKRHETEDL 301
           Y +    VGN    +RR+ K  GA++   EM  C+S L+G    +K  W      E +  
Sbjct: 12  YFAVAPMVGNSEEAWRRLSKRHGANIFYTEMVHCDSFLRGSRNPVKNRWYTTS--EGDRP 69

Query: 302 FGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361
              QICGN+P ++ + A ++Q++   D ID+N GCP  +  K G G+ +          V
Sbjct: 70  LVVQICGNSPEVMLEAALIIQDHC--DAIDVNFGCPQKVARKGGYGAYLQENWKLTGEIV 127

Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDW 419
           +  S  L++P   K+R  V+   + T      +   G SL+ VHGR+R+ R      + W
Sbjct: 128 KVLSSGLNVPVFCKIR--VFGSIEKTVEYAKMIEEAGCSLLAVHGRTRDQRGAAMGFASW 185

Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
           ++I    +     PV  NG+I ++ D     +      GVM+G   L  P IF
Sbjct: 186 KHIRAIKENLR-IPVLSNGNIMTHHDVWRCLEYT-GCDGVMVGEAHLHNPLIF 236


>UniRef50_A4RVX6 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 371

 Score = 91.1 bits (216), Expect = 8e-17
 Identities = 55/176 (31%), Positives = 91/176 (51%), Gaps = 6/176 (3%)

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM---HRLPALET 359
           GAQI G+ P+++   A+ L        IDLN GCP +++  KG GS ++     + A   
Sbjct: 68  GAQIMGSEPWLLELAARHLATEKSAPRIDLNCGCPANVVTGKGAGSSLLRDPEYVYACVK 127

Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419
           +V   ++      T+K+R+G Y D  +    +      GA  +++H R+R   Y+  ++W
Sbjct: 128 AVADGARGSGAHVTMKLRSG-YDDSSLLRENLLAAREAGARFVSLHARTRAQGYSGRANW 186

Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
           E I   A+     PV GNGD+ S +   E+ +++    G+M+GRGA+  P IF  I
Sbjct: 187 EEI-AFAKDVLDIPVLGNGDVTSPQRAAELLRVS-DADGIMLGRGAVQDPLIFRRI 240


>UniRef50_A3VNG3 Cluster: Dihydrouridine synthase TIM-barrel
           protein; n=5; Alphaproteobacteria|Rep: Dihydrouridine
           synthase TIM-barrel protein - Parvularcula bermudensis
           HTCC2503
          Length = 368

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 67/225 (29%), Positives = 105/225 (46%), Gaps = 7/225 (3%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA-QIC 307
           L+P++ + +LPFRR     GA +   EM   E  ++  + + AL     T D     Q+ 
Sbjct: 32  LAPMSGITDLPFRRAALRAGAPLVVSEMVASEEWVRE-RPDVALRAALPTGDSLNVIQLA 90

Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367
           G     + + A    E    D ID+N+GCP   +     GS +M  +    + ++     
Sbjct: 91  GREARWMREGAAKA-EALGADIIDINMGCPARKVTGLLSGSALMRDVDHALSLIKATLSG 149

Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427
            S P T+KMR G          I    ++ G ++ITVHGR+R+  Y  ++DW  +    +
Sbjct: 150 TSRPVTLKMRLGWDHGHLNAPEIAKGAADAGVAVITVHGRTRQQFYKGTADWRAVRATVE 209

Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWI 471
           A +  PV  NGDI   +D      +A +   GVMIGR A  +PW+
Sbjct: 210 AVS-VPVIVNGDI--VDDVTARAALAQSGAAGVMIGRAAEGRPWL 251


>UniRef50_A4S141 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 307

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 62/233 (26%), Positives = 105/233 (45%), Gaps = 8/233 (3%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFG 303
           N + +++P+     L FR +CK +GA +    M      ++  K    +      +    
Sbjct: 15  NPRYHVAPMVDQSELAFRELCKRYGATLGYTPMIHARLFVESPKYRREIFSTSTRDRPLL 74

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
           AQ C N+P I+ + A ++      D +D+N GCP  +  +   G+ +M     +E  +R 
Sbjct: 75  AQFCANDPEILLRAATMIAPYC--DGVDINFGCPQRIAKRGNYGAFLMDDWKTVEALIRK 132

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWEY 421
             + L +P T K+R  VY D + T      +   GA ++ VHGR+RE +      ++W Y
Sbjct: 133 LDEELPVPVTAKIR--VYDDLETTLKYAKMVEAAGAQIVAVHGRTREQKRCADIRANWAY 190

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
           I    + A   PV  NGDI S  +     + A    GV+     L  P +F++
Sbjct: 191 IR-AIKDALKVPVLANGDIRSLAEARACLE-ATGADGVLSAEPLLSNPALFSD 241


>UniRef50_A5K1E0 Cluster: tRNA-dihydrouridine synthase, putative;
           n=5; Plasmodium|Rep: tRNA-dihydrouridine synthase,
           putative - Plasmodium vivax
          Length = 340

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 61/230 (26%), Positives = 109/230 (47%), Gaps = 7/230 (3%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305
           K  L+P+  +  L FR +C+ +   +T   M   ++ ++  K   +  +  E ++   AQ
Sbjct: 27  KHILAPMVDLSELAFRLLCRNYNCHLTFTPMLHAKNFVEHEKYRKSYFQSCEKDEPVIAQ 86

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
            CGNN  II    + ++   E++ +DLN+GCP  +  K   G+ ++ +   +   V   +
Sbjct: 87  FCGNNSKIILNAIEYIK--NEVNAVDLNLGCPQQIAKKGNYGAFLLQKHDEVVNLVSDIT 144

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYT--KSSDWEYIE 423
              +IP T K+R  + QD + T  +   + +    +ITVHGR++E + T  K  D+E I+
Sbjct: 145 NNCNIPITCKIRK-IDQDYQKTLNLCYDLQSRNVKMITVHGRTKEEKGTNIKQCDYEIIK 203

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473
              +     P+  NG I  +ED  +          VM     L KP+ F+
Sbjct: 204 IIKERLN-IPIIANGSIEHFEDIQKCLNYT-KADAVMCAEILLEKPYFFS 251


>UniRef50_Q9JUP6 Cluster: tRNA-dihydrouridine synthase C; n=4;
           Neisseria|Rep: tRNA-dihydrouridine synthase C -
           Neisseria meningitidis serogroup A
          Length = 333

 Score = 89.0 bits (211), Expect = 3e-16
 Identities = 52/152 (34%), Positives = 82/152 (53%), Gaps = 5/152 (3%)

Query: 328 DFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS--IPFTVKMRTGVYQDKK 385
           D IDLN GCP   + +  GG+ ++     +   V+   + L   IP T KMR G Y+DK 
Sbjct: 102 DKIDLNFGCPAPTVNRHKGGAILLKEPELIFHIVKTLRERLPAHIPLTAKMRLG-YEDKS 160

Query: 386 ITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYED 445
                   ++  GA  +TVH R++   Y   + WE+I    + +   PV  NGD+FS +D
Sbjct: 161 PALECACAIAEGGACGLTVHARTKAEGYEPPAHWEWIRK-IRDSVDIPVTANGDVFSLQD 219

Query: 446 YVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
           Y+ ++ I+     VM+GRGA+I+P +  +IK+
Sbjct: 220 YIGIKTIS-GCNSVMLGRGAVIRPDLARQIKQ 250


>UniRef50_O52532 Cluster: tRNA-dihydrouridine synthase B; n=6;
           Gammaproteobacteria|Rep: tRNA-dihydrouridine synthase B
           - Serratia marcescens
          Length = 334

 Score = 89.0 bits (211), Expect = 3e-16
 Identities = 58/234 (24%), Positives = 106/234 (45%), Gaps = 7/234 (2%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           N L  +P+  + + PFR +C   GA +   EM      +    +    +   +   +   
Sbjct: 10  NCLIAAPMAGITDRPFRTLCHAMGAGMAVSEMLSSNPEVWRTDKSRLRMVHSDEPGIRSV 69

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           QI G +P  +   A++    +    ID+N+GCP   + +K  GS ++     ++  +   
Sbjct: 70  QIAGCDPDDMAAAARI-NVASGAQLIDINMGCPAKKVNRKLAGSALLQYPDLVKRILHAV 128

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
              + +P T+K+RTG   + +    I     + G   +T+HGR+R   +   ++++ I  
Sbjct: 129 VDAVDVPVTLKIRTGWAPEHRNCVEIAQLAEDCGIQALTIHGRTRACLFNGDAEYDSIRA 188

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIA--PTVKGVMIGRGALIKPWIFNEIK 476
             Q+ +  P+  NGDI    D  + R +        +MIGR A  +PWIF EI+
Sbjct: 189 VKQSVS-IPIIANGDI---TDPHKARAVLDYTGADALMIGRAAQGRPWIFREIQ 238


>UniRef50_O74553 Cluster: tRNA dihydrouridine synthase Dus4; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus4 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 326

 Score = 88.6 bits (210), Expect = 4e-16
 Identities = 60/228 (26%), Positives = 106/228 (46%), Gaps = 5/228 (2%)

Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309
           +P+     LPFR++ +++  D+    M L +  L   K  +     ++ +     Q   +
Sbjct: 25  APMVRYSKLPFRQLVRDYNTDIVYTPMILAKEFLHP-KGRYFDFSTNDADASLILQFGVD 83

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369
           +P I+ K AQL+     +D I +N GCP     ++G GS ++     +   VR     L 
Sbjct: 84  DPVILEKAAQLV--GPYVDGIGINCGCPQTWAIQEGIGSALLDEPEKVHKLVRAVKSTLG 141

Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429
             F  +++  + +D   T  ++  +   GA +ITVHGR+R+ R +   + + I    +  
Sbjct: 142 ESFCTEVKIRIAKDLNKTRHLMQVIEKSGADIITVHGRTRQDRSSFPVNLDAIRE-VRPC 200

Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
              PV  NGD+ S    +E+ K   T +G+M  RG L  P +F   +E
Sbjct: 201 VQIPVVANGDVKSLRKGLEIAKYTET-QGIMSARGLLENPALFAGYEE 247


>UniRef50_Q6P1R4 Cluster: tRNA-dihydrouridine synthase 1-like; n=20;
           Euteleostomi|Rep: tRNA-dihydrouridine synthase 1-like -
           Homo sapiens (Human)
          Length = 473

 Score = 87.8 bits (208), Expect = 7e-16
 Identities = 60/194 (30%), Positives = 104/194 (53%), Gaps = 12/194 (6%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRC 363
           Q C N+P +  + A L Q+    D IDLN+GCP  +I K+G  G+ +      L+  +  
Sbjct: 79  QFCANDPEVFVQAALLAQDYC--DAIDLNLGCP-QMIAKRGHYGAFLQDEWDLLQRMILL 135

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEY 421
           A + LS+P T K+R     DK + +     +   G  L+TVHGR++E +   + ++ WE+
Sbjct: 136 AHEKLSVPVTCKIRVFPEIDKTVRY--AQMLEKAGCQLLTVHGRTKEQKGPLSGAASWEH 193

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIW 481
           I+   + A   PV+ NG+I   +D VE       V+GVM   G L  P +F E +   +W
Sbjct: 194 IK-AVRKAVAIPVFANGNIQCLQD-VERCLRDTGVQGVMSAEGNLHNPALF-EGRSPAVW 250

Query: 482 DISSKDRFEILKKY 495
           ++ +++  +I++++
Sbjct: 251 EL-AEEYLDIVREH 263


>UniRef50_Q7UXK8 Cluster: Putative uncharacterized protein; n=3;
           Planctomycetaceae|Rep: Putative uncharacterized protein
           - Rhodopirellula baltica
          Length = 374

 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 70/231 (30%), Positives = 108/231 (46%), Gaps = 10/231 (4%)

Query: 252 LTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWA--LVKRHETEDLFGAQICGN 309
           L+   +LP R I +   A  T  E+ L + LL   K+E     +   + E   G Q+ G 
Sbjct: 45  LSGYSDLPMRVIARRHSASYTICEVMLDQFLLSLTKREKTRHFLDIADEEHPVGGQLMGA 104

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKK-GGGSGMMHRLPALETSVRCASKLL 368
            P   +  A  L E    D ID+N GCP+  +  +  GG  +     A+E   R    + 
Sbjct: 105 EPEQFSAGALKLVE-AGFDVIDVNFGCPVKKVLGRCRGGFHLSQPAVAIEILRRTRDVVP 163

Query: 369 S-IPFTVKMRTGVY---QDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
             IP TVKMR G+    + ++    I+    + G + +TVHGR+   RY   S W +++ 
Sbjct: 164 DHIPVTVKMRRGMDDTPESREQFFEILDGAIDAGLAGVTVHGRTVMQRYIGPSRWAFLKE 223

Query: 425 CAQ-AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
             Q       + G+GD+F+  D +EM +    + GV I RGA+  PWIF +
Sbjct: 224 VKQHVGDRLKILGSGDLFAAVDGLEMMR-QTGIDGVTIARGAIGNPWIFQQ 273


>UniRef50_Q7UKE8 Cluster: Putative uncharacterized protein; n=2;
           Planctomycetaceae|Rep: Putative uncharacterized protein
           - Rhodopirellula baltica
          Length = 364

 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 66/233 (28%), Positives = 102/233 (43%), Gaps = 14/233 (6%)

Query: 250 SPLTTVGNLPFRRICKEFG-ADVTCGEMA-------LCESLLKGLKQEWALVKRHETEDL 301
           +P+    N  FR I ++FG A +   EM        L E+  +   + W +    E   L
Sbjct: 33  APMAGFTNAAFRHIVRQFGGAGLLATEMVNARGFVWLDENEAEHPDRLWGVAD--EPRPL 90

Query: 302 FGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361
              QI  N+P  + KV + L E   +  +D+N GCP+  + +K      + R P    ++
Sbjct: 91  -AVQIWDNDPETMAKVGRRLAEEYRVSVVDINFGCPVRQVTEKAHSGSYLLREPNRMHAI 149

Query: 362 --RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419
             R        P T K+R G  ++    + I   +   GA+ +TVHGR+    +  ++DW
Sbjct: 150 ISRLVQVCAPTPVTAKIRLGCSRENINCNEIARVVEEAGAAALTVHGRTAADMFRGNADW 209

Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
           E I          P+ GNGD+ S E  V        V  VMI R  L +PW+F
Sbjct: 210 ERISEIKSHLRNIPLIGNGDLDSAEKVVAAFD-QYDVDAVMIARACLGRPWLF 261


>UniRef50_Q30WR3 Cluster: Dihydrouridine synthase family protein;
           n=3; Desulfovibrio|Rep: Dihydrouridine synthase family
           protein - Desulfovibrio desulfuricans (strain G20)
          Length = 376

 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 63/234 (26%), Positives = 108/234 (46%), Gaps = 11/234 (4%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEM--ALCESLL---KGLKQEWALVKRHET 298
           N +L+L+P+  +G++ +R++ + FG    CG +   +C +     +   +      R E 
Sbjct: 56  NGRLFLAPMAGLGHIAYRQVLESFGG---CGLVFTGMCSARAVPTENPARSPVFSWRPEE 112

Query: 299 EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALE 358
                 Q+ G +P  +   A+ + E+     +D+N+GC +  I KKG G+ ++       
Sbjct: 113 LPALVCQLFGADPQDMAAAARRV-ESEGFFGVDINMGCSVAPIVKKGCGADLLRDPERAV 171

Query: 359 TSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSD 418
             V    + +S+P  VKMRTG   D +    +  ++ + GA  +  H R    R T    
Sbjct: 172 RMVDAVRRAVSVPVFVKMRTGWSPDPEPAVNLARRLQDAGADALVFHPRVAPDRRTHRPR 231

Query: 419 WEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
             +I    + A   PV GNGD+F   D   M +      GV +GR A+ +PWIF
Sbjct: 232 TAHI-GLVKDAVDIPVIGNGDVFDAADCAAMLE-RTGCDGVSLGRLAIARPWIF 283


>UniRef50_Q9FH91 Cluster: Gb|AAF51525.1; n=6; Magnoliophyta|Rep:
           Gb|AAF51525.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 423

 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 64/232 (27%), Positives = 113/232 (48%), Gaps = 14/232 (6%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMA---LCESLLKGLKQEWALVKRHETEDLF 302
           K  ++P+     LPFR +C+++GA      M    +     K   QE+   K  E   LF
Sbjct: 89  KYIVAPMVDNSELPFRLLCQKYGAQAAYTPMLHSRIFTETEKYRNQEFTTCK--EDRPLF 146

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             Q C N+P  + + A+ ++     D++D+N+GCP  +  +   G+ +M  LP +++ V 
Sbjct: 147 -VQFCANDPDTLLEAAKRVEPYC--DYVDINLGCPQRIARRGNYGAFLMDNLPLVKSLVE 203

Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWE 420
             ++ L++P + K+R  ++ + + T      + + G SL+ VHGR+R+ +  K   +DW 
Sbjct: 204 KLAQNLNVPVSCKIR--IFPNLEDTLKYAKMLEDAGCSLLAVHGRTRDEKDGKKFRADWS 261

Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
            I+   + A   PV  NG++   ED     K    V+GV+     L  P  F
Sbjct: 262 AIKE-VKNAMRIPVLANGNVRCIEDVDNCIK-ETGVEGVLSAETLLENPAAF 311


>UniRef50_Q9VPM1 Cluster: CG3645-PA, isoform A; n=2; Diptera|Rep:
           CG3645-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 505

 Score = 86.2 bits (204), Expect = 2e-15
 Identities = 70/240 (29%), Positives = 111/240 (46%), Gaps = 13/240 (5%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLK-QEWALVKRHETEDLFGAQIC 307
           ++P+     L +R +C+ +GA++    M          K ++ AL    E   L   Q C
Sbjct: 32  VAPMVDQSELAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDALQTCPEDRPLI-IQFC 90

Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRCASK 366
           GN+   I   A L Q++   D +D+N+GCP   I K+G  GS +      L   V     
Sbjct: 91  GNDAQQILDAALLAQDHC--DAVDINLGCP-QAIAKRGHYGSFLQDEWELLTEIVSTLHA 147

Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEYIET 424
            L++P T K+R  +++D + T      +   G  L+TVHGR+RE +   T  ++W YI+ 
Sbjct: 148 KLAVPVTCKIR--IFEDLEKTIRYAKMLEAAGCQLLTVHGRTREQKGPLTGVANWNYIKN 205

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDIS 484
             Q     P+  NG+I + +D V        V GVM   G L  P IF  +    +W ++
Sbjct: 206 VRQ-HIKIPMLANGNILALDD-VHRCLTETGVDGVMSAEGNLHNPAIFKGV-SPPVWQMA 262


>UniRef50_Q9HGN6 Cluster: tRNA dihydrouridine synthase Dus1; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus1 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 399

 Score = 86.2 bits (204), Expect = 2e-15
 Identities = 68/234 (29%), Positives = 109/234 (46%), Gaps = 14/234 (5%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWA----LVKRHETEDL 301
           K  L+P+     LP+R + +  GAD+    M    S L G  +++       +    E  
Sbjct: 19  KRILAPMVDQSELPWRILARRSGADLCYSPMF--HSRLFGESEDYRNKVFSTRTIPEERP 76

Query: 302 FGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361
              Q CGN+P I+ K A++       D +D+N+GCP  +  K   GS +      +E+ +
Sbjct: 77  LIIQFCGNDPEIMLKAAKIAAPYC--DAVDVNLGCPQGIAKKGKYGSFLQENWNLIESII 134

Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDW 419
                 LSIP T K+R  ++ D + T      +   GAS++ VHGR RE +  +T  +DW
Sbjct: 135 TKLHTELSIPVTAKIR--IFPDPQKTLDYAKMILKAGASILAVHGRLREQKGHFTGIADW 192

Query: 420 EYIETCAQ-AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
           E I+   +   +   ++ NG+I   +D     K    V GV+   G+L  P IF
Sbjct: 193 EQIQMLRKNLPSETVLFANGNILHAQDIDRCIKYT-GVDGVLSAEGSLYNPRIF 245


>UniRef50_A6DU09 Cluster: Dihydrouridine synthase family protein;
           n=1; Lentisphaera araneosa HTCC2155|Rep: Dihydrouridine
           synthase family protein - Lentisphaera araneosa HTCC2155
          Length = 334

 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 58/218 (26%), Positives = 105/218 (48%), Gaps = 11/218 (5%)

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
           AQ+ G NP   ++      +    D +D+N+GCP+  I K+GG S +++     +  V  
Sbjct: 84  AQVWGKNPDKFSEAISKYVDPEVFDGVDINMGCPVAKIVKQGGCSALINTPEIAKELVLA 143

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
           A     +P +VK RTG+   K  T   +  +     + I +HGR+++ +    + W+ I 
Sbjct: 144 AKAATKLPVSVKTRTGITAHK--TEEWMTHLLEVEPAAIILHGRTQKQQSEGLASWDEIA 201

Query: 424 TCAQA----ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN-EIKEQ 478
             A+         P +GNGD+ S E   ++ +    + G MIGRG    PWIFN ++   
Sbjct: 202 KGARVRDRLKPHIPFWGNGDVRSIEQAHQLCQ-EHKLDGAMIGRGVFHNPWIFNTDLLGD 260

Query: 479 KIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRF 516
            +  +  +++  +L ++++     WGS  +   + RRF
Sbjct: 261 NV--LPPEEKIALLWRHASLYTSFWGSQ-KNFLTLRRF 295


>UniRef50_Q00RI1 Cluster: OSIGBa0125M19.5 protein; n=9;
           Magnoliophyta|Rep: OSIGBa0125M19.5 protein - Oryza
           sativa (Rice)
          Length = 319

 Score = 84.6 bits (200), Expect = 7e-15
 Identities = 68/248 (27%), Positives = 111/248 (44%), Gaps = 22/248 (8%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK-------GLKQEWALV 293
           +++ +KL L+P+  VG LPFR +  E+GAD+T GE  +    LK        L     L 
Sbjct: 1   MEYRDKLVLAPMVRVGTLPFRLLAAEYGADITYGEEIIDHKFLKCERVTNESLGTTDFLE 60

Query: 294 KRHET---------EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKK 344
           +  +T          D    Q+  ++     K AQL+  +     ID+N+GCP       
Sbjct: 61  RGTDTVVFRTCPQERDRVVFQMGTSDAVRALKAAQLVCNDVAA--IDINMGCPKSFSLSG 118

Query: 345 GGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITV 404
           G G+ ++ +   +   +    + L    T K+R  +   ++ T  +  ++   G   + V
Sbjct: 119 GMGAALLSKPELIHDILTTLRRNLDTTVTCKIR--LLNTRQDTVELARRVEKIGVPALAV 176

Query: 405 HGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRG 464
           HGR  + R    + W+ I     A +  PV  NGD+F YED+  + K A     VM+ RG
Sbjct: 177 HGRKVKDRPRDPAKWDEIADVVSALS-IPVIANGDVFEYEDFKRI-KDATGAASVMVARG 234

Query: 465 ALIKPWIF 472
           A+    IF
Sbjct: 235 AMWNASIF 242


>UniRef50_Q5LRN6 Cluster: TRNA-dihydrouridine synthase, putative;
           n=10; Rhodobacterales|Rep: TRNA-dihydrouridine synthase,
           putative - Silicibacter pomeroyi
          Length = 327

 Score = 84.2 bits (199), Expect = 9e-15
 Identities = 54/227 (23%), Positives = 97/227 (42%), Gaps = 3/227 (1%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308
           L+P+  + + PFR +  EFGA +   EM   + +++         +     +    Q+ G
Sbjct: 16  LAPMAGITDRPFRDLVMEFGAGMVVSEMVASQEMVQAKPGVRERAELSADVENTAVQLAG 75

Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL 368
            + + I + A+ + +      ID+N+GCP   +     GS ++         +      +
Sbjct: 76  RDTHWIAEAARQVADR-GARVIDINMGCPAKKVTNGYSGSALLKTPDHALRLIEAVVAAV 134

Query: 369 SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQA 428
            +P T+K R G          +  + +  G  ++T+HGR+R   Y   +DW  I    + 
Sbjct: 135 DVPVTLKTRLGWDDTLMNAPDVARRAAEAGVRMVTIHGRTRCQFYKGRADWAAI-AAVRE 193

Query: 429 ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
           A   P+  NGDI +               GVM+GRGA  +PW+  +I
Sbjct: 194 AVDVPLIANGDI-TCAHTARQALDRSGADGVMVGRGAQGRPWLLAQI 239


>UniRef50_Q54XQ6 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 435

 Score = 84.2 bits (199), Expect = 9e-15
 Identities = 64/236 (27%), Positives = 113/236 (47%), Gaps = 14/236 (5%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLL--KGLKQE-WALVKRHETEDLF 302
           K  ++P+     L FR +C+++GAD+    M   ++    K  +++ W+     E   L 
Sbjct: 53  KKTVAPMVDHTFLAFRMLCRKYGADMVYTPMFHSKNFATCKTYRRDYWSTCP--EDRPLV 110

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             Q CGN P  + K A+ ++++   D IDLN+GCP  +  +   GS ++ +   +   V+
Sbjct: 111 -VQFCGNEPEWVVKAAKYIEDHC--DAIDLNLGCPQQIARRGNYGSFLLDKPHIILPIVQ 167

Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWE 420
              K + +P   K+R     D  I   +  ++   G  L+T+HGR++E +   S  ++W+
Sbjct: 168 ELHKHIKVPIFCKIRLLPNLDDTI--KLALQLQEAGCQLLTIHGRTKEQKGHNSGIANWK 225

Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
            I T  +  +  PV  NG +  YED ++         GVM   G L  P  F+ +K
Sbjct: 226 AIRTIREQLS-IPVIANGSVVQYED-IDRCLEETGADGVMSAEGILANPSFFSGLK 279


>UniRef50_Q8YMN5 Cluster: Transcriptional regulator; n=5;
           Bacteria|Rep: Transcriptional regulator - Anabaena sp.
           (strain PCC 7120)
          Length = 349

 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 61/232 (26%), Positives = 115/232 (49%), Gaps = 8/232 (3%)

Query: 249 LSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQIC 307
           L+P+  V NL F ++   +G+ D    E        +  +   + +  ++T     AQ+ 
Sbjct: 29  LAPMQDVTNLWFMKVIAHYGSPDYFFTEYFRVNDTSRLNRGILSAITENDTGRPVFAQMI 88

Query: 308 GNN-PYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366
           G + P ++    +L   N  +  +DLN+GCP   IY+K  G G++     +E  +    +
Sbjct: 89  GESIPDLVRTAKELCGYN--IAGVDLNMGCPAPRIYRKNVGGGLLLSPAKVEQILEELRQ 146

Query: 367 LLSI-PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425
            ++  P TVKMR G +++    + I+  ++     L+++HGR+ +  Y  +  ++ I   
Sbjct: 147 AVNDRPLTVKMRVG-FENTDTFYEILDIVNRHNIDLLSLHGRTVKDMYHGAVKYDLIAEA 205

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
            +    CPV  NG+I S    +E+ +      GVM+GR A+  PW+FN+I++
Sbjct: 206 VRRVD-CPVLANGNIHSATTALEVLERTGAA-GVMVGRWAIGNPWLFNQIRQ 255


>UniRef50_A3RPJ2 Cluster: TRNA-dihydrouridine synthase; n=2;
           Proteobacteria|Rep: TRNA-dihydrouridine synthase -
           Ralstonia solanacearum UW551
          Length = 369

 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 61/202 (30%), Positives = 98/202 (48%), Gaps = 7/202 (3%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC--ASKLLSIPFTVKMRTGVYQDKKIT 387
           IDLN GCP  ++ + GGG+ ++     L T V    A+   +I  T KMR GV  D  + 
Sbjct: 136 IDLNFGCPAKVVNRHGGGAMLLSTPELLHTIVSAVRAAVPANIAVTAKMRLGV-SDTSLA 194

Query: 388 HTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYV 447
                 ++  GA+ + VH R+R+  Y   + W++I   A  A   PV  NG++++  D+ 
Sbjct: 195 IDCATALAEGGAASLVVHARTRDHGYRPPAHWDWIARIAD-AVEVPVIANGEVWTVADWE 253

Query: 448 EMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDT 507
             R ++     VMIGRGA+  P++   I+ Q     S+ +   +L+   +Y L+   +  
Sbjct: 254 RCRAVS-GCDDVMIGRGAVSDPFLAQRIRGQMERTPSNAEWPLVLRYLVDY-LKMLHARI 311

Query: 508 QGVESTRRFLLEWLSFLYRYVP 529
                  R  L WLS+L R  P
Sbjct: 312 AACHEHGRVKL-WLSYLKRTWP 332


>UniRef50_Q4PG83 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 527

 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 54/177 (30%), Positives = 86/177 (48%), Gaps = 8/177 (4%)

Query: 297 ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPA 356
           +T+     Q C N+P  + K A+++++    D +DLN+GCP  +  +   GS +M     
Sbjct: 130 DTDRPLFVQFCSNDPETLLKAAKVVEDRC--DAVDLNLGCPQHIARRGHYGSYLMEDWSL 187

Query: 357 LETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSR--EARYT 414
           + + +      L +P T KMR  VY+  + T T    +   GA +ITVHGR+R  +   T
Sbjct: 188 IFSLINILHVNLKVPVTAKMR--VYESVEKTITYARLLERAGAQIITVHGRTRNMKGHLT 245

Query: 415 KSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWI 471
             +DW  I    +A    PV+ NG++   +D+ +    A    GVM   G L  P I
Sbjct: 246 GLADWAKIRAVKEAVN-VPVFANGNVLYPQDFYD-ALAATGADGVMSAEGNLYNPAI 300


>UniRef50_Q4AHG7 Cluster: Dihydrouridine synthase, DuS; n=1;
           Chlorobium phaeobacteroides BS1|Rep: Dihydrouridine
           synthase, DuS - Chlorobium phaeobacteroides BS1
          Length = 337

 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 48/157 (30%), Positives = 80/157 (50%), Gaps = 2/157 (1%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389
           I+ N+GCP   +  K  GSGM+     +E+ ++  +  L +  +VK R G Y+D      
Sbjct: 93  INWNMGCPFPRVANKQRGSGMLPHPDLVESILQKITPQLPLNLSVKCRLG-YEDASEIDA 151

Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449
           ++P  +    S +TVH R  +  Y+   +W  I+         P   NGDIFS EDY + 
Sbjct: 152 LIPIFNEHRISELTVHARLGKQMYSGEVNWSAIQKLLNNLK-IPFAYNGDIFSVEDYQKF 210

Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSK 486
           +   P +  +MIGRG L  P++  ++K  ++ D+S +
Sbjct: 211 KITFPQINTLMIGRGLLTDPFLPAKLKGLELPDLSQQ 247


>UniRef50_UPI0000D5693C Cluster: PREDICTED: similar to
           dihydrouridine synthase 4-like; n=3; Coelomata|Rep:
           PREDICTED: similar to dihydrouridine synthase 4-like -
           Tribolium castaneum
          Length = 451

 Score = 81.8 bits (193), Expect = 5e-14
 Identities = 58/225 (25%), Positives = 100/225 (44%), Gaps = 5/225 (2%)

Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309
           +P+     L FR + K +  D+    M L +S  K  K        +  +     Q   N
Sbjct: 29  APMVRYSKLQFRNLVKSYNCDLCYTPMILADSFCKSGKARANEFTTNMNDTPLITQFAAN 88

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369
             Y     A ++  +   D +DLN GCP      +G G  M+ +   +   V+    ++ 
Sbjct: 89  KVYDFVGAAYMV--SPFCDGVDLNCGCPQRWAKLQGLGCIMLEKPEVIYDLVKQCRNVIP 146

Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429
            PFTV ++  + +D + +  I  ++ + G S +TVHGR+ + + T   + E +      +
Sbjct: 147 KPFTVSVKLRLQKDLRRSVEICRQLEHCGVSFLTVHGRTPD-QLTGEVNKEALNLIV-GS 204

Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
              PV  NG + S ED +E+++     KGVM+  G L  P +F E
Sbjct: 205 VNVPVVANGGVKSLEDCLELQE-KTNCKGVMVANGLLTNPTLFTE 248


>UniRef50_Q47C15 Cluster: Dihydrouridine synthase, DuS; n=2;
           Betaproteobacteria|Rep: Dihydrouridine synthase, DuS -
           Dechloromonas aromatica (strain RCB)
          Length = 319

 Score = 81.8 bits (193), Expect = 5e-14
 Identities = 51/183 (27%), Positives = 92/183 (50%), Gaps = 10/183 (5%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G++P+ + + A+ L        +DLN GCP   +++  GGS ++   P L   +  A
Sbjct: 69  QLLGSDPHFMAENARRLVALNPAG-VDLNFGCPAPTVFRHRGGSALLGE-PELLNEITSA 126

Query: 365 SKLL---SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
            + +    IPFT KMR G+  D          +   G + + VHGR+R   Y   + WE+
Sbjct: 127 VRSVVPAHIPFTAKMRLGI-DDTSRAIDCAQALEAAGINELIVHGRTRSDGYRPPARWEW 185

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKI- 480
           I+   + A   P+  NG++++ ED+    ++A     +M+GRGA+  P +   ++ ++  
Sbjct: 186 IDK-VRDAIHIPLIANGEVWTVEDFRNC-QLATGCADIMVGRGAVADPLLARRVRGEETG 243

Query: 481 -WD 482
            WD
Sbjct: 244 GWD 246


>UniRef50_Q5A4Y0 Cluster: Potential tRNA dihydrouridine synthase;
           n=2; Saccharomycetales|Rep: Potential tRNA
           dihydrouridine synthase - Candida albicans (Yeast)
          Length = 339

 Score = 81.4 bits (192), Expect = 6e-14
 Identities = 53/222 (23%), Positives = 97/222 (43%), Gaps = 3/222 (1%)

Query: 251 PLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNN 310
           P+     LPFR +C+ +  D+    M L    ++           ++++     Q+  NN
Sbjct: 32  PMVRYSKLPFRELCRFYDVDIVYTPMILAREFVRNEVARSTDFTTNDSDKCVIVQVGVNN 91

Query: 311 PYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSI 370
                K  +++  +  +D I +N GCPI    ++G G+ +M     +   ++ A      
Sbjct: 92  VDDFMKFIEMI--HPFVDGIGINCGCPIKEQVREGIGAALMSDPDLVAELIKTAKDKYGD 149

Query: 371 PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAAT 430
              +  +  +++D   T   V K+   G   +TVHGR++  R +   + + I+   +  T
Sbjct: 150 SICIDTKIRIHRDINQTIDFVNKVVEAGTDTLTVHGRTKNTRSSVPVNLDAIKIIRENVT 209

Query: 431 PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
             PV  NGD F+  D+ ++      V GVM  RG L  P +F
Sbjct: 210 TIPVIANGDCFTLTDFQKIVDYT-GVDGVMSARGVLANPALF 250


>UniRef50_A6W1E8 Cluster: Dihydrouridine synthase DuS; n=1;
           Marinomonas sp. MWYL1|Rep: Dihydrouridine synthase DuS -
           Marinomonas sp. MWYL1
          Length = 335

 Score = 81.0 bits (191), Expect = 8e-14
 Identities = 56/199 (28%), Positives = 95/199 (47%), Gaps = 6/199 (3%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G+N  ++ + A L         ID+N GCP   +   GGGS ++    AL   +   
Sbjct: 86  QLLGSNAELMAESA-LNATKAGAKHIDVNFGCPAKRVNGHGGGSVLLQTPDALYDIMSAI 144

Query: 365 SKLL--SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
              L   IP + K+R G ++D+ +    V  +   G   +T+HGR+++  Y   + WE I
Sbjct: 145 RDTLPSDIPVSAKIRLG-FEDEALLFDNVAAIEAAGVGTLTIHGRTKKDGYKPPARWEKI 203

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWD 482
               QA T   V  NGDI   +  +  + I    +  MIGRG+L  P++F +I+++    
Sbjct: 204 GEI-QAKTKMTVVANGDITDTKSLLRCQSITGC-QHFMIGRGSLNNPFVFQQIRKELNGQ 261

Query: 483 ISSKDRFEILKKYSNYGLE 501
            S+ D   + + + +Y  E
Sbjct: 262 ESTADTTNLNRLFISYSRE 280


>UniRef50_A1VHK2 Cluster: Dihydrouridine synthase, DuS; n=4;
           Desulfovibrionaceae|Rep: Dihydrouridine synthase, DuS -
           Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
          Length = 449

 Score = 81.0 bits (191), Expect = 8e-14
 Identities = 59/232 (25%), Positives = 105/232 (45%), Gaps = 4/232 (1%)

Query: 248 YLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQIC 307
           +L+PL    +L FR +C++ GA V C EM   + L+        L+     +     Q+ 
Sbjct: 35  WLAPLAGYSDLSFRLLCRKAGAAVCCTEMVSAKGLIYYSPGTRDLLATTPEDAPLVVQLF 94

Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367
           G +P I+ +  + L E     + DLN+GC +  + K G G+ M+  +P      R   + 
Sbjct: 95  GCDPDIMVRAMEPLLEQ-GFRWFDLNMGCSVPKVVKTGCGAAMLRDVPQALAVARAMLRT 153

Query: 368 LSI-PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426
                   K R G    +++   +   +++ GA  +T+H R     ++  + W  +    
Sbjct: 154 AGAGRVGFKFRLGWDVGQEVWADLGRALADLGAGWVTLHPRYARQGFSGEARWSTLGELV 213

Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478
           +A +  PV  +GD+F+  D V   +    V  VM  RGAL  P +F+  +E+
Sbjct: 214 RAVS-VPVIASGDLFTAADGVRCLR-ETGVASVMYARGALNDPGVFHAHRER 263


>UniRef50_Q5KP54 Cluster: TRNA dihydrouridine synthase, putative;
           n=1; Filobasidiella neoformans|Rep: TRNA dihydrouridine
           synthase, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 610

 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 53/170 (31%), Positives = 79/170 (46%), Gaps = 8/170 (4%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q C N+P I+   A+ ++     D +D+N GCP  +  +   GS +      +   +   
Sbjct: 155 QFCANDPDILLAAAKKVEHRC--DAVDINFGCPQGIAKRGHYGSFLQDEWELIHKLISTL 212

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSRE--ARYTKSSDWEYI 422
            + LS+P T K R  ++ D   T      M   GA ++T HGR+RE   + T  +DWEYI
Sbjct: 213 HENLSVPVTAKFR--IFPDLDKTIAYARMMEAAGAQILTCHGRTREMKGQNTGLADWEYI 270

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
               + A   PV+ NG+I   ED     ++     GVM   G L  P IF
Sbjct: 271 RE-VKKAVKVPVFANGNILYREDVDRCMEVT-GCDGVMTAEGNLSNPAIF 318


>UniRef50_Q8XYX1 Cluster: tRNA-dihydrouridine synthase C; n=26;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase C -
           Ralstonia solanacearum (Pseudomonas solanacearum)
          Length = 326

 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 49/152 (32%), Positives = 80/152 (52%), Gaps = 7/152 (4%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMM---HRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKI 386
           IDLN GCP  ++ + GGG+ ++     L  + ++VR A     I  T KMR GV  D  +
Sbjct: 93  IDLNFGCPAKVVNRHGGGAMLLATPELLHRIVSTVRAAVP-ARIAVTAKMRLGV-SDTSL 150

Query: 387 THTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDY 446
                  ++  GA+ + VH R+R+  Y   + W++I   A A    PV  NG++++ +D+
Sbjct: 151 AIACATALAEGGAASLVVHARTRDHGYRPPAHWDWIARIADAVR-VPVVANGEVWTVDDW 209

Query: 447 VEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478
              R ++     VMIGRGA+  P++   I+ Q
Sbjct: 210 ARCRAVS-GCDDVMIGRGAVSDPFLALRIRGQ 240


>UniRef50_A1SX05 Cluster: Dihydrouridine synthase, DuS; n=3;
           Alteromonadales|Rep: Dihydrouridine synthase, DuS -
           Psychromonas ingrahamii (strain 37)
          Length = 314

 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 58/175 (33%), Positives = 84/175 (48%), Gaps = 8/175 (4%)

Query: 305 QICGNNPYIITKVA-QLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
           Q+ G NP  + + A Q +   +  D IDLN GCP   + K  GG+ ++    AL   V  
Sbjct: 68  QLLGQNPQCLAENAHQAISIGS--DGIDLNFGCPAKTVNKNKGGAVLLKSPEALYQIVTE 125

Query: 364 ASKLLSI--PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
             K + +    +VK+R G Y+DK +       +   GA  + VH R++   Y   + W +
Sbjct: 126 VRKAVPVFQTLSVKIRLG-YEDKSLAIENAQAIQAAGADELAVHARTKAEGYRPPAHWHW 184

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
           I     A T  PV  NGDIFS +D     +I    + +MIGRGAL  P +   IK
Sbjct: 185 IAKIKDAIT-IPVTANGDIFSVDDAKRCMEITGCER-LMIGRGALATPNLAQAIK 237


>UniRef50_O95620 Cluster: tRNA-dihydrouridine synthase 4-like; n=28;
           Eumetazoa|Rep: tRNA-dihydrouridine synthase 4-like -
           Homo sapiens (Human)
          Length = 317

 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 59/237 (24%), Positives = 114/237 (48%), Gaps = 9/237 (3%)

Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309
           +P+     L FR + +++  D+    M +    +K +K   +    ++ +     Q   N
Sbjct: 32  APMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAAN 91

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369
           +  +++  A+++      + ID+N GCP      +G G+ ++++   ++  V+     + 
Sbjct: 92  DARLLSDAARIVCPYA--NGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQVE 149

Query: 370 IP-FTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQA 428
            P F+V ++  ++ D K T  +  K    G S ITVHGR+ E R+ +   ++ I+   + 
Sbjct: 150 TPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERH-QPVHYDSIKIIKEN 208

Query: 429 ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE---QKIWD 482
            +  PV  NGDI S ++   + +I  T  GVM+ RG L  P +F   +E   + IWD
Sbjct: 209 MS-IPVIANGDIRSLKEAENVWRITGT-DGVMVARGLLANPAMFAGYEETPLKCIWD 263


>UniRef50_Q9VY45 Cluster: CG1434-PA; n=6; Endopterygota|Rep:
           CG1434-PA - Drosophila melanogaster (Fruit fly)
          Length = 473

 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 71/256 (27%), Positives = 117/256 (45%), Gaps = 25/256 (9%)

Query: 236 RERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQ------- 288
           + R+ +D+ NKL L+P+  VG LP R +  E GAD+   E  +   L+K +++       
Sbjct: 15  KTRQRLDYRNKLILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLIKSIRRPNPALGT 74

Query: 289 -------EWALVKR---HETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPI 338
                  +  +V R    ET  L   Q+  ++      V +LLQ   ++  +D+N+GCP 
Sbjct: 75  VDFVDPSDGTIVFRTCAQETSRLV-LQMGTSDAGRALAVGKLLQR--DISGLDINMGCPK 131

Query: 339 DLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWG 398
           +   K G G+ ++         +R     L IP T K+R  +  D + T  +V K++  G
Sbjct: 132 EFSIKGGMGAALLADPDKAAHILRTLCSGLDIPVTCKIR--ILPDVEGTIDLVQKLAATG 189

Query: 399 ASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT--V 456
            + I +H R+R+ R    +  E +   AQ A   P+  NG   +   Y ++RK       
Sbjct: 190 IAAIGIHARTRDERPQHPAHPEVLRAVAQ-AVDIPIIANGGSKNMHCYDDLRKFQMECGA 248

Query: 457 KGVMIGRGALIKPWIF 472
             VM+ R A I   IF
Sbjct: 249 DSVMVARAAQINVSIF 264


>UniRef50_Q8A2H9 Cluster: Putative nifR3 family TIM-barrel enzyme
           with dihydrouridine synthase domain; n=6;
           Bacteroidales|Rep: Putative nifR3 family TIM-barrel
           enzyme with dihydrouridine synthase domain - Bacteroides
           thetaiotaomicron
          Length = 314

 Score = 79.4 bits (187), Expect = 2e-13
 Identities = 53/190 (27%), Positives = 92/190 (48%), Gaps = 5/190 (2%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389
           +D+N+GCP  L+ K+  GSG++     ++  +   ++   I F+VKMR G  Q  +    
Sbjct: 91  VDINLGCPFPLLAKRHNGSGILPYPEEVKALLSIVTRYPQISFSVKMRLGWEQPDECL-A 149

Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449
           + P +++     IT+H R  +  Y    D +      +     P+  NGDI + ED   +
Sbjct: 150 LAPILNDLPLRQITMHPRLGKQGYKGEVDLQGFSAFREVC-QLPLVYNGDIHNLEDIQRI 208

Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIKEQK-IWDISSKDRFEILKK--YSNYGLEHWGSD 506
               P++ G+MIGRG L  P +  E KE + +     +DR + + K  Y+NY +   G +
Sbjct: 209 STQFPSLAGIMIGRGLLANPALALEYKENRTLAPDEMRDRLKSMHKSVYNNYDVLLEGGE 268

Query: 507 TQGVESTRRF 516
            Q +   + F
Sbjct: 269 GQLLTKMKTF 278


>UniRef50_A7AQM0 Cluster: Dihydrouridine synthase, putative; n=1;
           Babesia bovis|Rep: Dihydrouridine synthase, putative -
           Babesia bovis
          Length = 355

 Score = 79.4 bits (187), Expect = 2e-13
 Identities = 62/229 (27%), Positives = 103/229 (44%), Gaps = 8/229 (3%)

Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309
           +P+     LPFR +C+ +  D+T   M      ++  K      +  + +    AQ+CG+
Sbjct: 17  APMVNQSELPFRLLCRRYNVDLTYTPMLHGRIFVENEKYRAVHFQTSDDDRPLIAQVCGD 76

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS-VRCASKLL 368
           +   IT+ A+LL+ +     +DLN+GCP   I K G     +   P L T  V   ++ +
Sbjct: 77  DAGTITQAARLLKGHVSA--VDLNLGCP-QAIAKDGHYGSFLLDEPDLVTGIVSRVTREV 133

Query: 369 SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTK--SSDWEYIETCA 426
            I  T K+R       + T  +   +   G   +TVHGR R  + T   ++DW+ I    
Sbjct: 134 GIAVTCKIRKVDKDSLQSTLNLCYSLEQSGCKALTVHGRHRSEKGTNVGAADWDAIR-II 192

Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
           ++    PV  NG I ++ D VE          VM     L +P++F+ I
Sbjct: 193 KSRLRIPVIANGGIETFAD-VERCLSYTGADAVMSSESLLERPYLFSGI 240


>UniRef50_A3JG66 Cluster: Putative uncharacterized protein; n=3;
           Gammaproteobacteria|Rep: Putative uncharacterized
           protein - Marinobacter sp. ELB17
          Length = 335

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 64/227 (28%), Positives = 107/227 (47%), Gaps = 17/227 (7%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G++P+++ +      E      +D+N GCP   + K  GG  +M R P L   +  A
Sbjct: 68  QLLGSDPHMMARHGAKAAELGATQ-VDINFGCPAKTVNKHKGGCVLM-REPELMHEITAA 125

Query: 365 SKLL---SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
            +      I  T KMR G Y D+ +       +   GA  I +H RS+   Y   + WE 
Sbjct: 126 VRQAVPADILVTAKMRLG-YDDRSMGVACAQALDAAGAGEIVIHARSKTDGYKPPAYWEE 184

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE---- 477
           I   A+ A    V  NGDIF+  DY   R+++     VMIGRG + +P +  +I+     
Sbjct: 185 IAK-AREAVKAKVIANGDIFTVADYWRCREVS-GCDDVMIGRGLVARPDLARQIRASQRG 242

Query: 478 QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFL 524
           + I  ++  +   ++++Y  Y L+ W  D      T R + +W+++L
Sbjct: 243 ESIELMTWPEALALVQEY-GYALQGWLEDKY---VTGR-IKQWMNYL 284


>UniRef50_Q9XVN8 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 527

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 73/281 (25%), Positives = 128/281 (45%), Gaps = 21/281 (7%)

Query: 226 TDEDLIKLLPRERKTIDWNNKL--YLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLL 283
           +DE + K L   ++T++ N ++   L+P+     L FR   +++GA +T   M      +
Sbjct: 53  SDETIEKNLRFWKETLE-NQRITKVLAPMVDQSELAFRMFTRKYGAQLTFTPMIHAHLFV 111

Query: 284 KG---LKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDL 340
                 +   ALVK          Q C N         +L+++    D +DLN+GCP  +
Sbjct: 112 NDGTYRRNSLALVKADRP---LVVQFCANKVDTFLAACRLVED--VCDGVDLNLGCP-QM 165

Query: 341 IYKKGG-GSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGA 399
           + K+G  GS +   +  +   V        +P + K+R  V  D++ T     ++ + GA
Sbjct: 166 VAKRGRYGSWLQDEVDLICEMVSAVRDYCRLPISCKIR--VRDDRQQTVEYAKRLVDAGA 223

Query: 400 SLITVHGRSREAR--YTKSSDWEYIETCAQA-ATPCPVYGNGDIFSYEDYVEMRKIAPTV 456
           +++TVHGR+R+ +   T  +DW  I    +A  +  PV  NG+I  +   VE    A   
Sbjct: 224 TMLTVHGRTRDMKGAETGLADWSRIRDVVEAVGSRVPVMANGNI-QFPGDVERCMQATGA 282

Query: 457 KGVMIGRGALIKPWIFNEIKEQ-KIWDISSKDRFEILKKYS 496
             +M   G L  P IF++       W I++ +  E  KK++
Sbjct: 283 VAIMSAEGLLYNPLIFDDANAHVDTWKIAA-EYLEYAKKFN 322


>UniRef50_P53759 Cluster: tRNA-dihydrouridine synthase 1; n=11;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 1 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 423

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 61/232 (26%), Positives = 104/232 (44%), Gaps = 13/232 (5%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMA---LCESLLKGLKQEWALVKRHETEDLFGAQ 305
           ++P+     L +R + + +GA +    M    L  +  K  +  W+ +     +     Q
Sbjct: 33  VAPMVDQSELAWRILSRRYGATLAYTPMLHAKLFATSKKYREDNWSSLDGSSVDRPLVVQ 92

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
            C N+P  +   A+L+++  + D +DLN+GCP  +  K   GS +M     +   +    
Sbjct: 93  FCANDPEYLLAAAKLVED--KCDAVDLNLGCPQGIAKKGHYGSFLMEEWDLIHNLINTLH 150

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWEYIE 423
           K L +P T K+R  ++ D + +      + + GA  +TVHGR RE +  K+  ++WE I+
Sbjct: 151 KNLKVPVTAKIR--IFDDCEKSLNYAKMVLDAGAQFLTVHGRVREQKGQKTGLANWETIK 208

Query: 424 TCAQAATPCPV-YGNGDIFSYEDYVE-MRKIAPTVKGVMIGRGALIKPWIFN 473
                     V + NG+I   ED    M  I      VM   G L  P +FN
Sbjct: 209 YLRDNLPKETVFFANGNILYPEDISRCMEHIG--ADAVMSAEGNLYNPGVFN 258


>UniRef50_A6GHV6 Cluster: Dihydrouridine synthase family protein;
           n=1; Plesiocystis pacifica SIR-1|Rep: Dihydrouridine
           synthase family protein - Plesiocystis pacifica SIR-1
          Length = 321

 Score = 78.2 bits (184), Expect = 6e-13
 Identities = 56/171 (32%), Positives = 82/171 (47%), Gaps = 8/171 (4%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMH---RLPALETSV 361
           Q+ G  P+ + + A+          IDLN GCP   +    GG+ ++    R+ A+  +V
Sbjct: 65  QLLGGEPHWMARAAETAVA-LGAPGIDLNFGCPAKTVNSSDGGATLLKDPCRVEAVTRAV 123

Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
           R A     +P TVK+R G ++D      I       GAS +T+HGR+R   Y    D+E 
Sbjct: 124 RAAVPA-ELPVTVKIRVG-WEDPSPVVEIARAAEAGGASWLTIHGRTRRQLYKPPVDYEA 181

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
           I   AQAA    V  NGD+F      E  + +      MIGRGA+ +P +F
Sbjct: 182 IGR-AQAAVSMAVVANGDLFGVPSLFEAAQRSGCT-AFMIGRGAMGRPELF 230


>UniRef50_Q884C6 Cluster: tRNA-dihydrouridine synthase C; n=8;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase C -
           Pseudomonas syringae pv. tomato
          Length = 317

 Score = 78.2 bits (184), Expect = 6e-13
 Identities = 51/173 (29%), Positives = 85/173 (49%), Gaps = 6/173 (3%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G++P  + + A    E      +DLN GCP   + +  GG+ ++     L T V   
Sbjct: 68  QLLGSDPVCLAENAAFACE-LGAPVLDLNFGCPAKTVNRSRGGAILLKEPELLHTIVSQV 126

Query: 365 SKLL--SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
            + +   IP T KMR G Y++          +++ GA+ I VH R++   Y   + WE+I
Sbjct: 127 RRAVPKDIPVTAKMRLG-YENTDGALDCARALADGGAAQIVVHARTKVDGYKPPAHWEWI 185

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
               Q     PV  NG+I++ ED+   R+I    + +MIGRG + +P +  +I
Sbjct: 186 AR-IQEVVKVPVVANGEIWTVEDWRRCREIC-GARDIMIGRGLVARPDLARQI 236


>UniRef50_Q7RX85 Cluster: Putative uncharacterized protein
           NCU00065.1; n=3; Pezizomycotina|Rep: Putative
           uncharacterized protein NCU00065.1 - Neurospora crassa
          Length = 629

 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 53/171 (30%), Positives = 79/171 (46%), Gaps = 8/171 (4%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q C N+P  +   A+L+      D +DLN+GCP  +  +   GS +      +   +   
Sbjct: 140 QFCANDPAYLLSAAKLVAPYC--DAVDLNLGCPQGIAKRGQYGSFLQENQELIFELINTL 197

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEYI 422
            K L IP T K+R  +   K+ T      +   GAS++TVHGR RE +   T  +DWEYI
Sbjct: 198 HKELDIPVTAKIR--ILDTKEATLKYAQNVLRAGASILTVHGRRREQKGHQTGLADWEYI 255

Query: 423 ETCAQ-AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
               +       ++ NG+I  + D +E    A    GVM   G L  P +F
Sbjct: 256 RYLRENLPKETVIFANGNILQHAD-LEKCLAATGADGVMSAEGNLSDPGLF 305


>UniRef50_Q06063 Cluster: tRNA-dihydrouridine synthase 4; n=10;
           Saccharomycetales|Rep: tRNA-dihydrouridine synthase 4 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 367

 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 52/224 (23%), Positives = 97/224 (43%), Gaps = 5/224 (2%)

Query: 251 PLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNN 310
           P+     LPFR++C+E+  D+    M L    ++      + +  +  +     Q+  NN
Sbjct: 45  PMVRYSKLPFRQLCREYNVDIVYSPMILAREYVRNEHARISDLSTNNEDTPLIVQVGVNN 104

Query: 311 PYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSI 370
              + K  +++      D I +N GCPI    ++G G  +++    L + V         
Sbjct: 105 VADLLKFVEMVAPYC--DGIGINCGCPIKEQIREGIGCALIYNSDLLCSMVHAVKDKYGD 162

Query: 371 PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAAT 430
              ++ +  +++    T  +  K+ + G   IT+HGR+R  R ++ ++ + I+   +  +
Sbjct: 163 KLRIETKIRIHEALDETVELCRKLCDAGVDWITIHGRTRRTRSSQPANLDAIKYIIENIS 222

Query: 431 P--CPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
               PV  NGD F   D   + K      GVM  RG L  P +F
Sbjct: 223 DKNVPVIANGDCFKLSDLERITKYT-GAHGVMAVRGLLSNPALF 265


>UniRef50_Q6MNE9 Cluster: Nitrogen regulation protein nifR3; n=1;
           Bdellovibrio bacteriovorus|Rep: Nitrogen regulation
           protein nifR3 - Bdellovibrio bacteriovorus
          Length = 352

 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 52/175 (29%), Positives = 83/175 (47%), Gaps = 4/175 (2%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           QI GN    I +  + L E    + ID+N+GCP+    K   G  +M         VR  
Sbjct: 80  QILGNEEDAIAESVKRLVE-WGAEAIDINMGCPVQKALKHNYGVALMGDPAYAAEVVRMT 138

Query: 365 SKLLSIPFTVKMR-TGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
            K  ++P +VK+R  G  ++     T V  +   GA+ + +H R+   +   ++DWE I+
Sbjct: 139 VKNSTVPVSVKLRAVGSTKEFDELLTFVSGLRQSGAAWVCLHPRTAAQKRRGNADWEQIK 198

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478
                A   PV GNGD+ +Y+D + M K        M GRG   +PW+  ++ E+
Sbjct: 199 Q-LHKAVDFPVIGNGDVQTYDDAINMLK-ETGCDMAMAGRGLAARPWMMWQLGEE 251


>UniRef50_A4E892 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 317

 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 49/148 (33%), Positives = 73/148 (49%), Gaps = 4/148 (2%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389
           ++LN+GCP   +  KG GSG +  L  LE  +    +   +P +VK R G+  D +    
Sbjct: 89  VNLNLGCPSGTVVAKGKGSGFLRNLDELEAFLSDVCERSPLPVSVKTRLGLENDDEY-ER 147

Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWE-YIETCAQAATPCPVYGNGDIFSYEDYVE 448
           ++        + + VH R ++ RYT     E Y ET  +A  P PV  NGDIF  ED   
Sbjct: 148 VLDLYCRMPLAELIVHPRVQKDRYTGLPRKEFYGETLERA--PFPVAYNGDIFDLEDMDA 205

Query: 449 MRKIAPTVKGVMIGRGALIKPWIFNEIK 476
           + +  P  + VM+GRG L  P +   +K
Sbjct: 206 LVEAYPGTRHVMLGRGLLANPALARMVK 233


>UniRef50_Q6AKJ6 Cluster: Putative uncharacterized protein; n=1;
           Desulfotalea psychrophila|Rep: Putative uncharacterized
           protein - Desulfotalea psychrophila
          Length = 354

 Score = 75.8 bits (178), Expect = 3e-12
 Identities = 38/151 (25%), Positives = 71/151 (47%), Gaps = 2/151 (1%)

Query: 328 DFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKIT 387
           D +D+N+GCP   + + G G+ +      +   V  A +   +  + K+R G    +   
Sbjct: 125 DGVDINLGCPAPSVRRGGAGAALAEDWDRVRDIVSSARRHTDLTLSAKIRVGHVGKEAHL 184

Query: 388 HTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYV 447
                 +   G  L+ VH R    ++ +   W+ +    +     P++ NG IFS +D  
Sbjct: 185 LDFCKMLEAEGVDLLAVHARYHGEKFCRKPRWQLLAPICEQLD-IPIFANGGIFSVDDAR 243

Query: 448 EMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478
              +++    G+M+GRGA+ +PW+FNEI  +
Sbjct: 244 RCLELSGAA-GLMLGRGAVERPWLFNEIARE 273


>UniRef50_Q9XWJ9 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 436

 Score = 75.8 bits (178), Expect = 3e-12
 Identities = 68/250 (27%), Positives = 116/250 (46%), Gaps = 28/250 (11%)

Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLK---QEWALVKRHETE 299
           + NK  L+P+   G  P R +C ++GAD+   E  + + L++  +   +    +     +
Sbjct: 5   YRNKKILAPMVRAGRTPLRLLCLKYGADLCYTEEIVDKKLIEATRVVNEALGTIDYRNGD 64

Query: 300 DLF--------GA---QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGS 348
           D+         G    QI  N+     K+AQ++ +  ++  ID+N+GCP       G G+
Sbjct: 65  DIILRLAPEEKGRCILQIGTNSGEKAAKIAQIVGD--DVAGIDVNMGCPKPFSIHCGMGA 122

Query: 349 GMM---HRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVH 405
            ++    ++  + TS++ A+K   +P T K+R  V  D + T  +V ++     S + VH
Sbjct: 123 ALLTQTEKIVDILTSLKSAAK---VPVTCKIR--VLDDPEDTLKLVQEIEKCRVSALGVH 177

Query: 406 GRSREARYTKSSDWEYIETCAQAATPCPVYGNG---DIFSYEDYVEMRKIAPTVKGVMIG 462
           GR R+ R       + I   AQA    PV  NG   +I  Y D+ + + +  T    MI 
Sbjct: 178 GRRRDERQPDKCRIDEIRDVAQAVQSIPVISNGLSDEIEQYSDFEKYQLLTET-SSTMIA 236

Query: 463 RGALIKPWIF 472
           R AL  P IF
Sbjct: 237 RKALSTPSIF 246


>UniRef50_Q1JWD3 Cluster: Dihydrouridine synthase, DuS; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep: Dihydrouridine
           synthase, DuS - Desulfuromonas acetoxidans DSM 684
          Length = 320

 Score = 75.4 bits (177), Expect = 4e-12
 Identities = 51/185 (27%), Positives = 86/185 (46%), Gaps = 9/185 (4%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G+    + + AQ++ +      ++LN+GCP         G  M+     +   +R  
Sbjct: 74  QLIGHRSESLAEAAQIVADLGGAH-VNLNMGCPFGRTTTGKTGGAMLQEPEKIGDCLRAI 132

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
                   +VK+R G Y D +    ++P    +G   I +H R+   +Y   +D   +  
Sbjct: 133 RAAFHGSVSVKVRAG-YDDPEQIFDLLPVFEKYGVDFIVLHPRTVVQKYADDAD-HAVTA 190

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTV--KGVMIGRGALIKPWIFNEIKEQKIW- 481
              AAT  PV  NGD+FS E     R++A      G+M+GRGA+  PW+F  I+ + +  
Sbjct: 191 RVVAATALPVIANGDLFSEE---RARQVAEQTGAAGLMLGRGAIADPWLFQRIRGRGVEP 247

Query: 482 DISSK 486
           DIS +
Sbjct: 248 DISQR 252


>UniRef50_A6PMB8 Cluster: Dihydrouridine synthase, DuS; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Dihydrouridine
           synthase, DuS - Victivallis vadensis ATCC BAA-548
          Length = 304

 Score = 75.4 bits (177), Expect = 4e-12
 Identities = 57/176 (32%), Positives = 82/176 (46%), Gaps = 6/176 (3%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ GN P +I   A    E      I+LN GCP   +   G G G +  L  + T+V   
Sbjct: 68  QLMGNRPEVIAAAAARFMELGAAG-INLNFGCPSRQVTSGGAGGGALRDLAGMVTTVETV 126

Query: 365 SKLL-SIPFTVKMRTGVYQDKKITHTIVPKMSNWG-ASLITVHGRS-REARYTKSSDWEY 421
            K + + P +VK+RTG ++       I+P ++  G  S   +H R+ RE     S   E 
Sbjct: 127 KKAIPASPLSVKLRTG-WESPDEMQRILPALAETGCVSAFFLHFRTVREQYRPVSGREER 185

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
            E   + A P PV  NGDI S +D  E+ +      GVM  RG L  P + N I++
Sbjct: 186 FEAGLRLAAPVPVVLNGDIDSPDDASELLE-RTGAAGVMCARGWLRDPLLLNRIRQ 240


>UniRef50_Q127F8 Cluster: Dihydrouridine synthase, DuS; n=3;
           Proteobacteria|Rep: Dihydrouridine synthase, DuS -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 344

 Score = 74.9 bits (176), Expect = 5e-12
 Identities = 55/176 (31%), Positives = 88/176 (50%), Gaps = 8/176 (4%)

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM---HRLPALETS 360
           AQ+ G++P  + + A  L        IDLN GCP  ++ + GGG+ ++     L A+ ++
Sbjct: 73  AQLLGSDPACMAENAARLATLGPAG-IDLNFGCPAAVVNRHGGGASLLKEPETLLAIVSA 131

Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420
           VR A     +P + KMR G   D +     +  ++  GA  + VH R++   Y   + WE
Sbjct: 132 VRRAVP-AGMPVSAKMRLGYNDDSRAVECAL-AIAEGGAGELVVHARTKAQAYKPPAYWE 189

Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
            I    +AA   PV  NG+I++ +D    R+ A     +MIGRGA+  P +   IK
Sbjct: 190 RIAD-IRAAVQIPVVANGEIWTVDDARRCRE-ASGCSMLMIGRGAVADPGLGLAIK 243


>UniRef50_UPI00015B403F Cluster: PREDICTED: similar to MGC79829
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to MGC79829 protein - Nasonia vitripennis
          Length = 346

 Score = 74.5 bits (175), Expect = 7e-12
 Identities = 52/231 (22%), Positives = 103/231 (44%), Gaps = 5/231 (2%)

Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309
           +P+     LPFR + +++  D+    M L +S ++  K   +    +E +     Q    
Sbjct: 19  APMVRYSKLPFRTLVRKYDCDICFTPMILADSFVQSSKARDSEFSTNEGDSPLIVQFAAK 78

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369
                 +  +++   +  + +DLN GCP     K G G+ ++ +   ++  V      + 
Sbjct: 79  EVDDFVEATEMVAPYS--NGVDLNCGCPQRWALKDGYGADLLTKPQLVKELVSNVRNRIP 136

Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429
            PFTV ++  + +D K T      + + G S +TVH R+ + R  +  D + ++   ++ 
Sbjct: 137 KPFTVSVKIRILKDIKKTIEFSRAIEHAGVSFLTVHARTPDMR-NEPIDLDSLK-LVRSC 194

Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKI 480
              P+  NG++ S+ED   + +      GVM+  G L  P IF+  K   +
Sbjct: 195 VHLPMIANGNVRSFEDAKTLYE-ESKCNGVMVAGGILTNPAIFSGYKNTPV 244


>UniRef50_A7T8A1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 137

 Score = 74.5 bits (175), Expect = 7e-12
 Identities = 32/63 (50%), Positives = 47/63 (74%), Gaps = 4/63 (6%)

Query: 364 ASKLLSIPFTVKMRTGVYQDKKIT---HTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420
           A +++ IP TVK+R G++ DKK T   H +V  + +WG  ++T+HGRSRE RYTKS+DW+
Sbjct: 53  AYQVIDIPLTVKIRAGIH-DKKYTWNAHKLVGNLRDWGTDMVTIHGRSREQRYTKSADWD 111

Query: 421 YIE 423
           YI+
Sbjct: 112 YIK 114


>UniRef50_Q5HJT5 Cluster: Probable tRNA-dihydrouridine synthase;
           n=41; Bacilli|Rep: Probable tRNA-dihydrouridine synthase
           - Staphylococcus aureus (strain COL)
          Length = 328

 Score = 74.5 bits (175), Expect = 7e-12
 Identities = 75/279 (26%), Positives = 130/279 (46%), Gaps = 23/279 (8%)

Query: 249 LSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLL--KGLKQEWALVKRHETEDLFGAQ 305
           L+P+  V ++ FR +  E    DV   E    ES    +G+      +   E E    A 
Sbjct: 16  LAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEQPMVAH 75

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
           I G+ P    + +  L +      IDLN+GCP+  + KKG GSG++ R P +   +  A+
Sbjct: 76  IWGDKPEQFRETSIQLAK-MGFKGIDLNMGCPVANVAKKGKGSGLILR-PDVAAEIIQAT 133

Query: 366 KLLSIPFTVKMRTGVYQDKK----ITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
           K   +P +VK R G Y+  +    + H     ++N     +++H R+R+      + WE 
Sbjct: 134 KAGGLPVSVKTRLGYYEIDEWKDWLKHVFEQDIAN-----LSIHLRTRKEMSKVDAHWEL 188

Query: 422 IETCA----QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
           IE       + A    +  NGDI   +  +E+ +    + GVMIGRG    P+ F   KE
Sbjct: 189 IEAIKNLRDEIAPNTLLTINGDIPDRKTGLELAE-KYGIDGVMIGRGIFHNPFAFE--KE 245

Query: 478 QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRF 516
            +  + +SK+  ++L+ + +   ++   + +  +S RRF
Sbjct: 246 PR--EHTSKELLDLLRLHLSLFNKYEKDEIRQFKSLRRF 282


>UniRef50_Q9VJ06 Cluster: CG10495-PA; n=2; Sophophora|Rep:
           CG10495-PA - Drosophila melanogaster (Fruit fly)
          Length = 396

 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 59/227 (25%), Positives = 100/227 (44%), Gaps = 6/227 (2%)

Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309
           +P+     L FRR+ +  G  +    M + +S+    K           +    AQ    
Sbjct: 28  APMVRYSKLEFRRLVRLNGVQLAFTPMMISDSINNSEKARQNEFSTGADDQPLIAQFAAK 87

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369
           +P      AQL+     +D IDLN GCP      KG G GM+ +   +   V+   + L 
Sbjct: 88  DPTEFVTSAQLIYPY--VDGIDLNCGCPQSWAMAKGYGCGMLRQPELVHQVVQEVRRTLP 145

Query: 370 IPF--TVKMR-TGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426
             F  +VKMR  G  +  + T  +  ++ + G + +T+HGR+   +++K +      +  
Sbjct: 146 GDFSVSVKMRLLGGEESLQRTIDLARQLESAGVTFLTLHGRTPAQKHSKDTLDIPAMSQV 205

Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473
           + +   P+  NG++ SY D  +M +      GVM  RG L  P +FN
Sbjct: 206 RQSLQIPLIVNGNVESYRDACDMHE-QTGAAGVMAARGLLANPALFN 251


>UniRef50_Q6AJ40 Cluster: Putative uncharacterized protein; n=1;
           Desulfotalea psychrophila|Rep: Putative uncharacterized
           protein - Desulfotalea psychrophila
          Length = 318

 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 43/147 (29%), Positives = 74/147 (50%), Gaps = 2/147 (1%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389
           I+ N+GCP  ++ KK  GSGM+     +   +      + +  ++K R G Y +   T  
Sbjct: 92  INWNLGCPAPMVAKKKRGSGMLAHPDLIVEFLEEVLPQIPVKLSIKTRLG-YSNTAQTKE 150

Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449
           ++P++  +  + I +H R  +  Y  ++D +    C Q +     Y NGDI + E + E+
Sbjct: 151 LLPRLDQFPLTEIIIHARLGKQMYKGTTDPDTFAECLQLSQHRIAY-NGDITTLEHFHEL 209

Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIK 476
           +   P V+  MIGRGAL  P++   IK
Sbjct: 210 QTRFPQVEHWMIGRGALADPFLAERIK 236


>UniRef50_Q9NX74 Cluster: tRNA-dihydrouridine synthase 2-like; n=27;
           Eumetazoa|Rep: tRNA-dihydrouridine synthase 2-like -
           Homo sapiens (Human)
          Length = 493

 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 75/281 (26%), Positives = 127/281 (45%), Gaps = 37/281 (13%)

Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVT-CGE-----MALCESLLKGLKQEWALV--- 293
           ++NKL L+P+  VG LP R +  ++GAD+  C E     M  C+ ++  +      V   
Sbjct: 10  YHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDFVAPD 69

Query: 294 --------KRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG 345
                   +R +   +F  Q+  ++      VA+L++   ++  ID+N+GCP     K G
Sbjct: 70  DRVVFRTCEREQNRVVF--QMGTSDAERALAVARLVEN--DVAGIDVNMGCPKQYSTKGG 125

Query: 346 GGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVH 405
            G+ ++     +E  +    K    P T K+R  +    + T ++V ++   G + I VH
Sbjct: 126 MGAALLSDPDKIEKILSTLVKGTRRPVTCKIR--ILPSLEDTLSLVKRIERTGIAAIAVH 183

Query: 406 GRSREARYTKSSDWEYIETCAQAATPCPVYGNG----DIFSYEDYVEMRKIAPTVKGVMI 461
           GR RE R       E I+  A   +  PV  NG     I  Y D  + R+ A     VM+
Sbjct: 184 GRKREERPQHPVSCEVIKAIADTLS-IPVIANGGSHDHIQQYSDIEDFRQ-ATAASSVMV 241

Query: 462 GRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEH 502
            R A+  P IF  +KE        +   E+++KY  Y +++
Sbjct: 242 ARAAMWNPSIF--LKE------GLRPLEEVMQKYIRYAVQY 274


>UniRef50_A7AAN4 Cluster: Putative uncharacterized protein; n=2;
           Bacteroidales|Rep: Putative uncharacterized protein -
           Parabacteroides merdae ATCC 43184
          Length = 320

 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 52/220 (23%), Positives = 100/220 (45%), Gaps = 5/220 (2%)

Query: 292 LVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM 351
           LV    T      Q+   +P    ++A L +E+      D+N+GCP  +  ++  G+G++
Sbjct: 54  LVPEANTSASLVPQMIAASPEEFRRIAGLFRESGYRR-ADINLGCPFPMQARQHRGAGIL 112

Query: 352 HRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREA 411
                ++  +    +   I F+VK+R G +   +    ++P ++    + +T+H R    
Sbjct: 113 PYPDEVKVLLETIFEFPEIQFSVKLRLG-WDSPEEAQALLPFLNGLPLTHLTLHPRIGTQ 171

Query: 412 RYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWI 471
           +Y   +D         + T  P++ NGDI +  D   +    P +KG+MIGRG L  PW+
Sbjct: 172 QYKGKTDLSAFSRFYDSCT-LPLFYNGDIRTLPDIRSLTGRFPRLKGIMIGRGLLSSPWL 230

Query: 472 FNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVE 511
             E        ++++++ E L  +    L  + S  +G E
Sbjct: 231 ATEYISDT--PLTAQEKIEKLSAFHALLLAGYSSRLEGGE 268


>UniRef50_Q73RG6 Cluster: Dihydrouridine synthase, putative; n=1;
           Treponema denticola|Rep: Dihydrouridine synthase,
           putative - Treponema denticola
          Length = 337

 Score = 71.7 bits (168), Expect = 5e-11
 Identities = 73/261 (27%), Positives = 115/261 (44%), Gaps = 20/261 (7%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           KL  +P+  + +  FRR+   F   D    EM    S + G   E    + + + +    
Sbjct: 2   KLISAPMAAITHSAFRRLAACFKEPDEYFSEMIHAPSAISGGGFEKWYFRANPSPEKLVW 61

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS---- 360
           QI   +         LL +      IDLN+GC    I   G G   M + P  ET+    
Sbjct: 62  QITSPDEKSAAACVPLLLQYGGFG-IDLNMGCCAPQIVNTGAGFAWMKK-PLSETASLVS 119

Query: 361 -VRCASKLLS----------IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSR 409
            V+ A  L            I  +VK+R G  ++     +    + + G  LIT+H R++
Sbjct: 120 KVKKAVLLYDEQKAGPQTEPIRLSVKLRLGEEENYDRLLSFCKMLVSEGVDLITLHPRTQ 179

Query: 410 EARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKP 469
           + +Y++    EY    A   +  PVYGNGDI S E   ++    P   G MIGR A+ KP
Sbjct: 180 KQKYSRPCKHEYTARLASDLS-VPVYGNGDINSLETLEKIASKYPCA-GWMIGRAAVQKP 237

Query: 470 WIFNEIKEQKIWDISSKDRFE 490
           WIF E+ +  + + +++D+ E
Sbjct: 238 WIFYELSKGILKNGTAEDKDE 258


>UniRef50_Q4D174 Cluster: Dihydrouridine synthase (Dus), putative;
           n=2; Trypanosoma cruzi|Rep: Dihydrouridine synthase
           (Dus), putative - Trypanosoma cruzi
          Length = 548

 Score = 71.7 bits (168), Expect = 5e-11
 Identities = 49/177 (27%), Positives = 83/177 (46%), Gaps = 7/177 (3%)

Query: 297 ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPA 356
           ET+     Q CGN+   +   A+ ++++ E   +D+N+GCP  +  +   GS +M     
Sbjct: 177 ETDHPLFVQFCGNDADTLLAAARHVEDDCEA--VDVNLGCPQGIARRGHYGSFLMEDWDR 234

Query: 357 LETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS 416
           +   + C +  L +P T KMR  V+ D  +T      + + G +++ VHGR+R  +    
Sbjct: 235 VHNILHCLAVELRVPVTAKMR--VFDDDALTLKYAEMLRDTGIAVLCVHGRTRHNK-RGI 291

Query: 417 SDWEYIETCAQ-AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
           +D E I    +      PV GNG++ ++ED V     A    G M     L  P +F
Sbjct: 292 ADMEKIRRVREHLRGSIPVIGNGNVLTFED-VRRNMSATMTDGYMCAEPLLWDPRLF 347


>UniRef50_A6VYA3 Cluster: TIM-barrel protein, yjbN family; n=8;
           Proteobacteria|Rep: TIM-barrel protein, yjbN family -
           Marinomonas sp. MWYL1
          Length = 341

 Score = 70.9 bits (166), Expect = 9e-11
 Identities = 59/235 (25%), Positives = 103/235 (43%), Gaps = 16/235 (6%)

Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334
           EM    +LL+G   E   ++  E E     Q+ G++   + K A++  E    D ++LN+
Sbjct: 49  EMVTTGALLQGNHPE-RFLRYDECEHPIALQLGGSDAVALGKCAKMA-EQAGFDEVNLNV 106

Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGV--YQDKKITHTIVP 392
           GCP D +     G+ +M     ++ ++R      SIP T+K R G+   +D  +    V 
Sbjct: 107 GCPSDRVQNSLIGACLMAHPDKVKEAMRAMQDNCSIPVTIKHRIGLDDQEDYSVVRDFVG 166

Query: 393 KMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444
            ++  G +   VH R+        +E R      + Y+    +      +  NG I + +
Sbjct: 167 DVATTGVTTFIVHARNAILEGLSPKENREVPPLKYHYVHQLKKDFPDLEIIINGGIKTLD 226

Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKI-WDISSKDRFEILKKYSNY 498
              E ++    V GVM+GR A   PWI +++ E          DR+E L+ +  Y
Sbjct: 227 ---ECKEQLAHVDGVMVGREAYHNPWILSQVDEVLFGGQPLVNDRYEALEAFVPY 278


>UniRef50_Q5KPM6 Cluster: Putative uncharacterized protein; n=2;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 407

 Score = 70.9 bits (166), Expect = 9e-11
 Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 8/172 (4%)

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
           AQ    N   +   A+L+  +  +D IDLN GCP    Y +G G  ++ +   +   VR 
Sbjct: 154 AQFASPNAKSLADAAELI--SPYVDGIDLNCGCPQRWAYNEGIGCALLRKPELVRDMVRG 211

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW---E 420
               +   + V ++  +  +++ T  ++      G S +T+HGR+R    T   +    +
Sbjct: 212 VKDRMGWGWPVSIKIRIDSEQEKTEQLISNALQAGISHLTIHGRTRHQPSTDPVNLPGIK 271

Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
           +   C +   PC    NGD++  ED  +MR +   V+GVM  RG L  P +F
Sbjct: 272 FAVDCVKGEVPC--VANGDVWELEDARQMR-LHTGVQGVMAARGLLANPALF 320


>UniRef50_Q4WRF0 Cluster: Dihydrouridine synthase family protein,
           putative; n=9; Pezizomycotina|Rep: Dihydrouridine
           synthase family protein, putative - Aspergillus
           fumigatus (Sartorya fumigata)
          Length = 541

 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 52/173 (30%), Positives = 82/173 (47%), Gaps = 8/173 (4%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q C N+P    + A+ +      D +DLN+GCP  +  K   G+ +      +   +   
Sbjct: 130 QFCANDPDDFLEAARHVAPYC--DAVDLNLGCPQGIARKGHYGAFLQEDWDLIYKLINRL 187

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEYI 422
            K L IP T K R  + + K+ T      + + GAS+IT+HGR+RE +   T  +DW YI
Sbjct: 188 HKELPIPVTAKFR--IQESKEKTLEYAKMILSAGASIITLHGRTREQKGHNTGLADWSYI 245

Query: 423 ETCAQAATP-CPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
                   P   ++ NG+  +++D +E    A    GVM   G L  P IF++
Sbjct: 246 RYLRDNLPPETVIFANGNNLNHDD-LERCLEATGADGVMSAEGNLSDPAIFSK 297


>UniRef50_UPI0000499E32 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 339

 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 59/229 (25%), Positives = 105/229 (45%), Gaps = 9/229 (3%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHET-EDLF 302
           N +  L+P+    +L FR + +  G ++    M L +  ++       +V   +  E   
Sbjct: 21  NPQNILAPMVDGSDLTFRILVRRHGVNLCYTPMVLSKMFVESKVYRNEVVNSLDPKEQPI 80

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             QI G++   + + A+ LQ  +  D ID+N+GCP  +  K   G+ +       +  V 
Sbjct: 81  IIQIVGSDANEMARTAKFLQ--SYCDAIDINLGCPQKIAQKGNYGAYLALDFDHTKEIVN 138

Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWE 420
              + ++IP   K+R  V++D++ T   V  +   G   I VHGR+   + + +  + W 
Sbjct: 139 AVIEAVNIPVYCKVR--VFEDEEKTMRFVEMLQECGIWGIAVHGRTITEKQSMNYHARWN 196

Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKP 469
           YI    +     PV  NG++ S E   E +K+  +  G MIG G L+ P
Sbjct: 197 YIAKIKE-RLKIPVIANGEMRSREKIEECKKVTHS-DGYMIGFGLLMNP 243


>UniRef50_Q1N033 Cluster: Putative uncharacterized protein; n=1;
           Oceanobacter sp. RED65|Rep: Putative uncharacterized
           protein - Oceanobacter sp. RED65
          Length = 321

 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 48/174 (27%), Positives = 81/174 (46%), Gaps = 6/174 (3%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G++P  + + A    E      +++N GCP   +  + GG+ ++     + T +   
Sbjct: 68  QLLGSDPVAMAENACRAAE-LGAPVVNINFGCPSRFVNGRCGGAYLLQFPDQIHTILESV 126

Query: 365 SKLL--SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
            K L   +P T KMR G ++D  +       M + G   I +H R++   Y   + W  I
Sbjct: 127 RKALPEHVPLTAKMRLG-FKDDALALANAQAMESAGVRDICIHARTKVQGYRPPAHWHQI 185

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476
           +   Q     P+  NG+I++  DY E  K A   + VM+GRGA+  P +   IK
Sbjct: 186 KNIKQ-QVKVPIIANGEIWNRRDY-EACKAASHCEHVMLGRGAVADPELAATIK 237


>UniRef50_Q0IFC6 Cluster: tRNA-dihydrouridine synthase; n=2;
           Culicidae|Rep: tRNA-dihydrouridine synthase - Aedes
           aegypti (Yellowfever mosquito)
          Length = 391

 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 59/244 (24%), Positives = 105/244 (43%), Gaps = 8/244 (3%)

Query: 231 IKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEW 290
           ++ L RE +  D   K+  +P+     L FR + + +G D+T   M + +S  +  K   
Sbjct: 10  VEHLFREARAKDSYLKI-CAPMVRYSKLEFRNLVRSYGTDLTFTSMIMADSFCQSEKARL 68

Query: 291 ALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGM 350
                +  +    AQ    N        ++      +D +DLN GCP     + G GS +
Sbjct: 69  NEFTTNRDDTPVIAQFAAKNAVDFLSATEMTFPY--VDGVDLNCGCPQRWAMQDGYGSAL 126

Query: 351 MHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTI--VPKMSNWGASLITVHGRS 408
           +     +   +    + L   F+V ++  + Q K ++ TI    ++   G + ITVHGR+
Sbjct: 127 LRTPELIADMLSTVRRNLPSTFSVSVKVRLLQ-KSLSATIDMCRQLEACGITFITVHGRT 185

Query: 409 REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIK 468
              +     + E ++   +++   PV  NGDIFS +D  +         GVM  RG L  
Sbjct: 186 PAQKTNIPVNQEALKE-IKSSLGIPVVANGDIFSLQD-ADAMHCKTNCDGVMSARGILSN 243

Query: 469 PWIF 472
           P ++
Sbjct: 244 PAMY 247


>UniRef50_A6P2M8 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 311

 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 42/150 (28%), Positives = 76/150 (50%), Gaps = 2/150 (1%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389
           ++LN+GCP   +  KG GSG++ R   LE  +        +  ++K R G++  ++  H 
Sbjct: 81  VNLNLGCPSGTVTAKGKGSGLLARREELEQLLDGIFAAAPMAISIKTRLGMHDPEEFGH- 139

Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449
           ++   + +  + +TVH R R   Y K    EY +   + +   P+  NGDI +  D+ + 
Sbjct: 140 LLELYNRYPVAELTVHPRIRGDFYKKPVRPEYFDLAVRMSR-APLCYNGDIITPGDWEKA 198

Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIKEQK 479
            +  P V+ VMIGRG +  P +   +K ++
Sbjct: 199 SQRWPGVETVMIGRGLVADPSLAGRLKGEQ 228


>UniRef50_A4AAB0 Cluster: TRNA-dihydrouridine synthase C; n=2;
           unclassified Gammaproteobacteria|Rep:
           TRNA-dihydrouridine synthase C - Congregibacter
           litoralis KT71
          Length = 328

 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 48/167 (28%), Positives = 80/167 (47%), Gaps = 6/167 (3%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           QI G +P ++ + A    E      +DLN GCP   + +  GGS ++     +   V   
Sbjct: 74  QILGGDPSVVAENASRAAE-LGAPGVDLNFGCPAKTVNRSDGGSIILREPERVHRIVAAT 132

Query: 365 SKLL--SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
            + L  S+P +VK+R G     +    IV  +     S + +H R+R   Y   + WE+I
Sbjct: 133 RQALPPSVPLSVKIRLGFDSSDRFL-DIVSGIDAARPSELVIHARTRADGYRPPAYWEHI 191

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKP 469
              A++ T  P+  NG+I+   D    R+ + T + +M+GRG L +P
Sbjct: 192 -ALARSKTRLPLIANGEIWGVGDAKLAREKSGT-RDLMLGRGVLCRP 236


>UniRef50_O74731 Cluster: tRNA dihydrouridine synthase Dus2; n=1;
           Schizosaccharomyces pombe|Rep: tRNA dihydrouridine
           synthase Dus2 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 479

 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 60/248 (24%), Positives = 113/248 (45%), Gaps = 26/248 (10%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWAL-------- 292
           ++++NK+ L+P+  +G LP R +   +GA++  G   + ++LL G   E  +        
Sbjct: 4   LNYSNKVCLAPMVRIGELPMRLLALRYGANLVWGPEIVDKALLSGTPVERVVNDRINCID 63

Query: 293 -VKRHETEDLFGA----------QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLI 341
            VK    + LF            Q+   +P +  + A+L+    ++  IDLN GCP    
Sbjct: 64  FVKPPSNKVLFRVHPLEANRLIFQLGSASPELAVEAAKLVAN--DVAGIDLNCGCPKHFS 121

Query: 342 YKKGGGSGMMHRLPALETSVRCASKLLSIPF--TVKMRTGVYQDKKITHTIVPKMSNWGA 399
              G G+G++     L + +      +  P+  ++  +  + + K+ T  +V ++ + G 
Sbjct: 122 VHAGMGAGLLKNQDRLVSILDALVNEIGKPYKISISCKIRLLETKEDTLKLVERICDTGV 181

Query: 400 SLITVHGRSREARYTKSSDWEYIETCAQAA--TPCPVYGNGDIFSYEDYVEMRKIAPTVK 457
             ITVH R+   R T+ +D  Y+             +  NGD+ SY D +++ +    V 
Sbjct: 182 RAITVHCRTTPMRNTEPADRSYLSEIVGVCRNKDVSILVNGDVLSYNDGLDVIE-KYGVD 240

Query: 458 GVMIGRGA 465
           GV+I R A
Sbjct: 241 GVLIARAA 248


>UniRef50_Q54QJ2 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 402

 Score = 68.5 bits (160), Expect = 5e-10
 Identities = 61/249 (24%), Positives = 112/249 (44%), Gaps = 19/249 (7%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLK------------- 287
           +D+ NK  ++P+  VG  P R +   +G D+   E  +   L+K  +             
Sbjct: 28  MDYYNKKIMAPMVRVGTYPMRILAYNYGCDIAYSEELIDLKLMKSTRVVNEKLKTIDFIA 87

Query: 288 QEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGG 347
           ++  L  R   +D+      G    +    A  +  N ++  +D+N+GCP     + G G
Sbjct: 88  KDQTLCYRTSEKDVRNVLQLGTASSMTALEAAKVVCN-DICALDINMGCPKFFSVQGGMG 146

Query: 348 SGMMHRLPALETSVRCASKLLS-IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHG 406
           S ++ +   ++  +    + L+ IP T K+R  +  D++ T  ++  + + G S I VH 
Sbjct: 147 SALLSKPETIKDILTTLKRNLNGIPITCKIRL-LSTDQE-TIDLLRIIESTGVSAIGVHC 204

Query: 407 RSREARYTKSSDWEYIETC-AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465
           R    R    + W+ +E   + A+   P+  NGDIF + D +E  K    V  +MI RG 
Sbjct: 205 RMIPERPRDPAHWDRLENILSNASFSVPIIANGDIFEHAD-IEKIKKQTKVDSIMIARGV 263

Query: 466 LIKPWIFNE 474
           +    IF++
Sbjct: 264 VKNVSIFSK 272


>UniRef50_Q4S086 Cluster: Chromosome undetermined SCAF14784, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14784,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 505

 Score = 68.1 bits (159), Expect = 6e-10
 Identities = 45/144 (31%), Positives = 76/144 (52%), Gaps = 8/144 (5%)

Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSD 418
           VR AS+ LS+P T K+R  V+++ + T      +   G  L+TVHGR++E +   T  + 
Sbjct: 146 VRLASEKLSVPITCKIR--VFKEMEKTVRYAQMLEKAGCQLLTVHGRTKEQKGAMTGVAS 203

Query: 419 WEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478
           WE+I    QA    PV+ NG+I    D     +    V+GVM   G L  P +F E +  
Sbjct: 204 WEHIRAVRQAVN-IPVFANGNIQHLSDVTRCLQ-ETGVQGVMSAEGNLHNPALF-EGRSP 260

Query: 479 KIWDISSKDRFEILKKYSNYGLEH 502
            +W++ +++  E+++K+    L +
Sbjct: 261 PVWEM-AEEYLEVVRKHPPCSLSY 283



 Score = 36.3 bits (80), Expect = 2.3
 Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 3/41 (7%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG 345
           Q C N+P +  + A L Q+    D IDLN+GCP  +I K+G
Sbjct: 56  QFCANDPEVFVQAALLAQDYC--DAIDLNLGCP-QMIAKRG 93


>UniRef50_Q21L63 Cluster: Dihydrouridine synthase, DuS; n=1;
           Saccharophagus degradans 2-40|Rep: Dihydrouridine
           synthase, DuS - Saccharophagus degradans (strain 2-40 /
           ATCC 43961 / DSM 17024)
          Length = 318

 Score = 68.1 bits (159), Expect = 6e-10
 Identities = 52/175 (29%), Positives = 78/175 (44%), Gaps = 6/175 (3%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G+NP  +   A    E   +  IDLN GCP   + +  GG+ ++     +   V   
Sbjct: 73  QLLGSNPSALAANAARAAELGAVA-IDLNFGCPAKTVNRHKGGACLLDETDTVFDIVNAV 131

Query: 365 SKL--LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
            K    S P T K+R G Y ++         +   GA+ + VH RS+   Y   + W YI
Sbjct: 132 RKATPASTPVTAKIRLG-YLNRDSYLRNAKAIEAAGANELCVHARSKTDGYQPPAYWHYI 190

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
                  +  PV  NG+I+S ED+    +        M+GRG L KP +  EIK+
Sbjct: 191 GDIRDNLS-IPVVANGEIWSLEDFKRCAE-QSKCSDFMLGRGLLAKPDLALEIKQ 243


>UniRef50_A4BWB1 Cluster: Putative uncharacterized protein; n=5;
           Bacteroidetes|Rep: Putative uncharacterized protein -
           Polaribacter irgensii 23-P
          Length = 317

 Score = 68.1 bits (159), Expect = 6e-10
 Identities = 44/194 (22%), Positives = 94/194 (48%), Gaps = 4/194 (2%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389
           ++ N+GCP  ++ K+G GSG++     + + +        I  ++KMR G Y++ +    
Sbjct: 90  LNWNLGCPYPMVTKRGMGSGLISDAEKINSILHKVHNESDILVSMKMRMG-YENPEEILG 148

Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449
           ++P +  +    I +H R  +  Y   +D E  + C   +    +Y NGDI S   + ++
Sbjct: 149 VLPILDTYPLKNIAIHARIGKQLYKGGTDLEAFQKCLDNSKH-KMYYNGDITSVVAFHKL 207

Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQG 509
           ++  P++   MIGRG +  P++ + IK         K+RF++ +++ +   + + +   G
Sbjct: 208 QERFPSIDHWMIGRGLIGDPFLPSMIKADT--TEYPKERFDVFREFHDRIYQEYDAALSG 265

Query: 510 VESTRRFLLEWLSF 523
               +  +L +  F
Sbjct: 266 PTPIKMKMLGFWEF 279


>UniRef50_Q7VKU5 Cluster: tRNA-dihydrouridine synthase C; n=118;
           Gammaproteobacteria|Rep: tRNA-dihydrouridine synthase C
           - Haemophilus ducreyi
          Length = 325

 Score = 68.1 bits (159), Expect = 6e-10
 Identities = 67/232 (28%), Positives = 105/232 (45%), Gaps = 21/232 (9%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G  P  + + AQL  E      ID N GCP   +    GG+ ++ + P L   + CA
Sbjct: 73  QLLGQYPQWLAENAQLAIELGSYG-IDFNCGCPSKTVNGSHGGAALL-KDPEL---IYCA 127

Query: 365 SKLL------SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARY-TKSS 417
           +K +      + P +VKMR G +        I   +   GA  ITVHGR+++  Y  +  
Sbjct: 128 TKAIREAVPKAQPVSVKMRLG-WDCASQCFEIADAIQQAGADEITVHGRTKQDGYRAERI 186

Query: 418 DWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
           +W+ I    Q     PV  NG+I  +    + R+I     G+MIGRGAL  P +   IK 
Sbjct: 187 NWQAIGQIQQRLN-IPVIANGEILDFNSAQKCREITACC-GLMIGRGALNTPNLSKVIK- 243

Query: 478 QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVP 529
             +  ++  +  ++L +Y N   E       G     R + +WL +L +  P
Sbjct: 244 YNVAKMAWSEVLQLLYEYVNMPNER----DSGFYHVAR-IKQWLHYLDKAYP 290


>UniRef50_UPI00015B40A4 Cluster: PREDICTED: similar to
           tRNA-dihydrouridine synthase; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           tRNA-dihydrouridine synthase - Nasonia vitripennis
          Length = 505

 Score = 67.7 bits (158), Expect = 8e-10
 Identities = 67/255 (26%), Positives = 116/255 (45%), Gaps = 23/255 (9%)

Query: 238 RKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWAL----- 292
           R  + + +KL ++P+  +G LP R +  E+GAD+   E  +   LL+ +++   +     
Sbjct: 50  RPRLTYADKLIMAPMVRIGTLPMRLLALEYGADIVYTEELIDWKLLRSVRRVNEVLGTVD 109

Query: 293 -VKRHETEDLFGAQICGNNPYIIT----------KVAQLLQENTELDFIDLNIGCPIDLI 341
            + R +   +F       +  ++           KVA+L+++  ++  ID+N+GCP    
Sbjct: 110 YIDRTDGTIVFRTSPIERDRVVLQLGTCDANRALKVAKLVEQ--DVAGIDVNMGCPKRFS 167

Query: 342 YKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASL 401
              G G+ ++ +       +R     LSIP T K+R  V  + + T  +V  + + G S 
Sbjct: 168 ILGGMGAALLKQPEKASEILRTLVGGLSIPVTCKIR--VLGNVEDTLKLVDTLVDTGISA 225

Query: 402 ITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTV--KGV 459
           ITVHGR+ + R    +  E+I+  A+ A   PV  NG     E   ++ K         V
Sbjct: 226 ITVHGRTVDERPQHPNRSEFIKRVAEHA-KIPVIANGGSKEIEKRADIFKFKKETGCSSV 284

Query: 460 MIGRGALIKPWIFNE 474
           MI R A     IF E
Sbjct: 285 MIARAAEWNCSIFRE 299


>UniRef50_A2DYY3 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 313

 Score = 67.7 bits (158), Expect = 8e-10
 Identities = 70/248 (28%), Positives = 107/248 (43%), Gaps = 26/248 (10%)

Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCG----EMALCESLLKGLKQEWALVKR--- 295
           + NKL  +P+    +L FR  C E+GAD+       ++A+  S ++      +L+K    
Sbjct: 9   YKNKLIAAPMVRGSSLSFRLACLEYGADLVFSPGLVDLAIIGSTMEKDDNNISLIKVENG 68

Query: 296 ------HETEDLFGAQICG----NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG 345
                 H T +  G  I      + P  I K A +  E      ID+N GCP      +G
Sbjct: 69  HNRRIFHTTAEERGKLIIQLITVDGPNAI-KAADMCTEFAS--GIDINCGCPESFACHRG 125

Query: 346 GGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVH 405
           GGS M  +L +    V+       +P +VKMR     ++ +       M + GA  ITVH
Sbjct: 126 GGSKM--QLESAVDVVKTLKMNSPLPISVKMRVKDTVEESL--QFAKAMVDAGAVAITVH 181

Query: 406 GRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465
           GR    +   S D+E+++        C   GNG I +  D  EMR +      +MI   A
Sbjct: 182 GRLAADKRHGSVDYEHMKEIFDNIN-CAKIGNGGICNKADAAEMR-VKTGCDSIMIATAA 239

Query: 466 LIKPWIFN 473
           L  P +F+
Sbjct: 240 LKNPSVFS 247


>UniRef50_Q57V78 Cluster: TRNA-dihydrouridine synthase 1, putative;
           n=1; Trypanosoma brucei|Rep: TRNA-dihydrouridine
           synthase 1, putative - Trypanosoma brucei
          Length = 520

 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 48/173 (27%), Positives = 82/173 (47%), Gaps = 10/173 (5%)

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
           AQ CGN+P  +   A+ +++  E   +D NIGCP  +  +   GS +M     L   +  
Sbjct: 158 AQFCGNDPETVLAAARHVEDYCEA--VDFNIGCPQGIARRGHYGSFLMEDWELLHNILHA 215

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSRE--ARYTKSSDWEY 421
            +  L +P T KMR  ++ D+ +T      + + G  ++ VHGR+RE   +  + +D   
Sbjct: 216 LAVELRVPVTAKMR--IFDDEALTLKYAEMLRDTGIYVLCVHGRTRENKGQQQQPADLRM 273

Query: 422 IETCAQ-AATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIF 472
           I    +      P+  NG++ ++ED    R +A T  +G M     L  P +F
Sbjct: 274 IRRVHEHLRGSIPIIANGNVLTFEDV--PRNLAITGCEGYMCAEPLLWDPKLF 324


>UniRef50_O31546 Cluster: Probable tRNA-dihydrouridine synthase 2;
           n=10; Bacilli|Rep: Probable tRNA-dihydrouridine synthase
           2 - Bacillus subtilis
          Length = 325

 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 73/280 (26%), Positives = 124/280 (44%), Gaps = 15/280 (5%)

Query: 249 LSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLK--GLKQEWALVKRHETEDLFGAQ 305
           L+P+  V ++ FR +  E G  DV   E    ES     G       +   E E    A 
Sbjct: 16  LAPMEDVTDVVFRHVVSEAGRPDVFFTEFTNSESYCHPDGKDSVRGRLTFTEDEQPIVAH 75

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365
           I G+ P    K++  + E      +D+N+GCP+  +   G GSG++ R PA+   +  A+
Sbjct: 76  IWGDKPENFRKMSIGMAE-LGFKGLDINMGCPVPNVAGNGKGSGLICR-PAVAAELIQAA 133

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425
           K   +P +VK R G Y D       +  +     + +++H R+R       + WE I   
Sbjct: 134 KAGGLPVSVKTRLG-YTDVDEWREWLTHILKQDIANLSIHLRTRAEMSKVDAHWELIPEI 192

Query: 426 A----QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIW 481
                + A    +  NGDI   +  +++ +    V G+MIGRG    P+ F   KE K  
Sbjct: 193 KKLRDEVAPDTLLTINGDIPDRQTGLKLAE-QYGVDGIMIGRGIFTNPFAFE--KEPK-- 247

Query: 482 DISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWL 521
           + SSK+  ++L+ + +   E+   + +  +   RF   +L
Sbjct: 248 EHSSKELLDLLRLHLDLHDEYSKEEARPYKPLPRFFKIYL 287


>UniRef50_UPI000023EA9A Cluster: hypothetical protein FG07217.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG07217.1 - Gibberella zeae PH-1
          Length = 510

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 50/173 (28%), Positives = 77/173 (44%), Gaps = 8/173 (4%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q C N+P  +   A+  Q     D +DLN+GCP  +  K   G+ +      +   +   
Sbjct: 107 QFCANDPDALLSAAK--QVAPYCDAVDLNLGCPQGIARKGKYGAFLQEDQDLIFRLINIL 164

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEYI 422
            K L +P T K+R  +   K+ T      +   GAS++TVHGR RE +   T  ++W+ I
Sbjct: 165 HKELPVPVTAKIR--ILDTKEETLAYAQNVLKAGASILTVHGRKREQKGHLTGLAEWQMI 222

Query: 423 ETCAQA-ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
                +      ++ NG+I    D +E    A    GVM   G L  P IF +
Sbjct: 223 RFLRDSLPKETVIFANGNILQEGD-IEKCLEATGADGVMSAEGNLSDPAIFTK 274


>UniRef50_Q6MNE4 Cluster: Dihydrouridine synthase family protein;
           n=1; Bdellovibrio bacteriovorus|Rep: Dihydrouridine
           synthase family protein - Bdellovibrio bacteriovorus
          Length = 323

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 40/150 (26%), Positives = 73/150 (48%), Gaps = 5/150 (3%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL--SIPFTVKMRTGVYQDKKIT 387
           +DLN GCP   + +  GG+ ++     +   V    K +   +P T K+R G + D    
Sbjct: 92  VDLNFGCPAKTVNRHDGGASLLKSCDRVFNIVDTVRKAVPADVPVTAKIRLG-FDDPTKC 150

Query: 388 HTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYV 447
             I   +    A+ +TVH R++   Y   + W++I    +  T   +  NG+I++  D+ 
Sbjct: 151 LEIAQAVEEANATWLTVHCRTKTDGYKPPAYWDWIPKIKEK-TKIKLIANGEIWNVADFN 209

Query: 448 EMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
              ++    +  MIGRG +  P+IF++IK+
Sbjct: 210 RCVEVTQC-EDYMIGRGVMSNPFIFSQIKQ 238


>UniRef50_Q583Y8 Cluster: TRNA-dihydrouridine synthase 4, putative;
           n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 4,
           putative - Trypanosoma brucei
          Length = 419

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 57/227 (25%), Positives = 93/227 (40%), Gaps = 10/227 (4%)

Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309
           +P+       FR++C+ +G D++   M + +S         A    +  E     Q+  +
Sbjct: 64  APMVRCSRPAFRKLCRLWGTDISYTHMIMADSFACSEAARQAEFSIYSGETRLITQLASS 123

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL- 368
           +       A ++      D IDLN GCP   +   G G+ ++     +  +VRC    L 
Sbjct: 124 SGPTAATAAAIVAP--WCDAIDLNCGCPQRRVMADGLGAALLRNPEVVADTVRCVRNALE 181

Query: 369 ---SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425
               +P  VKMR  V  D +++     +    GA+ ITVHGR+          ++ I T 
Sbjct: 182 GGVELPCVVKMR--VKDDVRLSVDFARQCEAAGAAWITVHGRTPNCSAHAPVRFDAINTI 239

Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
            + A   PV  NG +      ++   +   V GVM G G L  P  F
Sbjct: 240 RE-ALGVPVVANGGVRDPSTALQ-AALTAGVGGVMSGMGLLANPACF 284


>UniRef50_A2F0D1 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 333

 Score = 65.7 bits (153), Expect = 3e-09
 Identities = 71/269 (26%), Positives = 110/269 (40%), Gaps = 23/269 (8%)

Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQE----------WAL 292
           +  K++  P+    NLPFR +C E GAD   G     +S+L     E          W  
Sbjct: 9   YRGKIFAGPMVRASNLPFRLMCLENGADGVYGPATSVDSILASHYDENEDPYTMYFGWPK 68

Query: 293 ---VKRHETEDLFGA---QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG 346
              V  H      G    QI  N+     + A ++ +    D IDLN GCP      +G 
Sbjct: 69  NPHVHFHTDPKEKGKLIFQILTNDASKAVQAASVVVKFA--DAIDLNCGCPESFATSRGT 126

Query: 347 GSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHG 406
           GS +M     +   V    +  ++P +VK R     ++ I   +     N GAS I VHG
Sbjct: 127 GSSLMSEPEIVADVVSALRRNYNVPISVKHRIHHNIEESIQFAVA--CENAGASAIAVHG 184

Query: 407 RSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGAL 466
           R +E +   S  ++ ++          + GNG + + E   EM +     + V+I   AL
Sbjct: 185 RLKEQKNKGSVAYDNMKLVFDHLHVAKI-GNGGVKNREMAKEMME-KTGCESVIISSAAL 242

Query: 467 IKPWIFNEIKEQKIWDISSKDRFEILKKY 495
             P IF+   E     ++ +   EI K+Y
Sbjct: 243 KNPTIFSGHPETDPVKLARR-YLEIAKQY 270


>UniRef50_A1AT39 Cluster: Dihydrouridine synthase, DuS; n=7;
           Desulfuromonadales|Rep: Dihydrouridine synthase, DuS -
           Pelobacter propionicus (strain DSM 2379)
          Length = 342

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 46/191 (24%), Positives = 85/191 (44%), Gaps = 4/191 (2%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G+    +   +Q  Q+      I+LN+GCP   +     G GM+     L + +   
Sbjct: 98  QLIGHGREALVSGSQAAQD-AGAAHINLNMGCPYGRMTSGQTGGGMLRSPQELSSIIPAL 156

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
            K +   F++K+R+G Y + +    ++P     G   + +H R+   +Y   +D      
Sbjct: 157 RKTIRGTFSIKLRSG-YDNPRQIFDLLPLFEASGVDFLVLHPRTVLQKYAGFADHGITAE 215

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDIS 484
             Q +T  P+  NGDI S      + +      G+M+GRGA+  P +F  ++     D  
Sbjct: 216 AVQRST-LPIIANGDIRSVATGRHVLR-ETGAAGLMLGRGAISDPLLFQRLRNCAPPDPQ 273

Query: 485 SKDRFEILKKY 495
            ++R  +L +Y
Sbjct: 274 PQERAAMLSRY 284


>UniRef50_Q09504 Cluster: Uncharacterized tRNA-dihydrouridine
           synthase-like protein C45G9.2; n=2; Caenorhabditis|Rep:
           Uncharacterized tRNA-dihydrouridine synthase-like
           protein C45G9.2 - Caenorhabditis elegans
          Length = 284

 Score = 64.9 bits (151), Expect = 6e-09
 Identities = 50/216 (23%), Positives = 101/216 (46%), Gaps = 6/216 (2%)

Query: 258 LPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKV 317
           L FR++ + +  DV    M   ++ ++  K   + +   E +     Q   ++P+++++ 
Sbjct: 7   LAFRQLVRVYDVDVCFTPMIYAKNFIESEKCRSSELSVCEGDSPLIVQFATDDPFVLSEA 66

Query: 318 AQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIP-FTVKM 376
           A+++ + +    +DLN GCP   +  KG GS ++ +   L   VR     +  P F+V +
Sbjct: 67  AEMVYKCST--GVDLNCGCPKHDVRSKGFGSALLSKPELLADMVRQTRARIPDPDFSVSL 124

Query: 377 RTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYG 436
           +  +  D + T  +  K    G + +TVHGR+   R  +  D + +     + +  P+  
Sbjct: 125 KIRINHDIEKTVDLCRKAEAAGVTHLTVHGRTPSQR-AEPIDIQALRIVKDSVS-VPIIA 182

Query: 437 NGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
           NG I + E+ + + +    V G+M   G L  P +F
Sbjct: 183 NGGITTREEALFLAE-QTGVDGIMAANGLLDNPALF 217


>UniRef50_A4BCJ5 Cluster: NifR3/Smm1 family protein; n=2;
           Gammaproteobacteria|Rep: NifR3/Smm1 family protein -
           Reinekea sp. MED297
          Length = 314

 Score = 64.5 bits (150), Expect = 8e-09
 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 6/173 (3%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G++P  + + A L         +DLN GCP   +    GG+ ++    ++   VR  
Sbjct: 68  QLLGSHPQALAENA-LRAIELGSHGLDLNFGCPSKTVNASKGGAVLLTEPESIYAVVRSV 126

Query: 365 SKLLSIPFTV--KMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
              L    T+  KMR G ++D  +       + + GA+ I VH R+++  YT  + W ++
Sbjct: 127 RDALPGDQTLSAKMRLG-FEDNSLMWECAHAIRDGGANEIIVHARTKQQGYTPPAYW-HL 184

Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
               +A    P+  NG+I++  D    +  A     +M+GRGA+  PW+ +EI
Sbjct: 185 PADFEARLGIPMIINGEIWTPADAGRAQHEA-NCSSIMLGRGAVRNPWLASEI 236


>UniRef50_A2FU21 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 322

 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 53/198 (26%), Positives = 97/198 (48%), Gaps = 12/198 (6%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ GN+   +   A+ LQ+      ID+N GC   +  +   G  M++     +  +   
Sbjct: 76  QMSGNDESELIACAKDLQQFAV--GIDINCGCTQHIARRGQYGYFMVNNENKRKNVIEMV 133

Query: 365 SKL---LSIPFTVKMRTGVYQDKK----ITHTIVPKMSNWGASLITVHGRSREARYTKSS 417
             +   +++P ++K R    +D K    IT     ++ + G SLI+VHGR++ +      
Sbjct: 134 KNIVASINVPLSIKFRLIDGEDGKPDVDITCKFAKELEDAGVSLISVHGRAKNSNKAGPV 193

Query: 418 DWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477
           D E I   A++ +  PV  NG + + E+ +EM K +    GVM+G+G L+ P  F++  E
Sbjct: 194 DAEAIRKIAESVS-IPVMANGGVRTKEEAIEMFKESHAA-GVMVGQGLLMNPKAFSDTPE 251

Query: 478 QKIWDISSKDRFEILKKY 495
                I S++  ++ K+Y
Sbjct: 252 HDPVAI-SREYLQLWKEY 268


>UniRef50_Q22A31 Cluster: TIM-barrel protein, yjbN family; n=1;
           Tetrahymena thermophila SB210|Rep: TIM-barrel protein,
           yjbN family - Tetrahymena thermophila SB210
          Length = 480

 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 52/207 (25%), Positives = 89/207 (42%), Gaps = 13/207 (6%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ GN+P  + K A++ +E    D ++LN+GCP D +     G+ +M     +   +R  
Sbjct: 163 QLGGNDPDNLAKAAKICEE-IGYDEVNLNVGCPSDRVQSGKFGACLMKEPELVAEIMRKM 221

Query: 365 SKLLSIPFTVKMRTGV--YQDKKITHTIVPKMSNWG-ASLITVHGRS--------REARY 413
            +  SIP TVK R GV  +   +     +  +S  G      VH R          + R 
Sbjct: 222 KEACSIPVTVKCRLGVDNFDSYEFARDFIKTVSEKGQVQHFVVHARKAFLKGLNPAQNRN 281

Query: 414 TKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473
                ++Y+    Q         NG   +Y+   ++ K    + G M+GR A   PW+F+
Sbjct: 282 VPPLKYDYVLRLKQEFPHLHFSINGGFKTYDQISDILKQENGLHGCMLGRAAYETPWLFS 341

Query: 474 EIKEQKIWDIS-SKDRFEILKKYSNYG 499
           ++  +     +    R EIL+ +  YG
Sbjct: 342 DMDRRYFGKQNPGFSRREILQIWGQYG 368


>UniRef50_Q550J6 Cluster: Putative uncharacterized protein; n=2;
           Dictyostelium discoideum|Rep: Putative uncharacterized
           protein - Dictyostelium discoideum AX4
          Length = 392

 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 10/179 (5%)

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIY--KKGGGSGMMHRLPALETSV 361
           AQ  GN P    + A++  E    D +D+N+GCP   +   K+  G+ ++      +  V
Sbjct: 72  AQFFGNKPEYFYESAKIANE-LGYDGVDINMGCPSRKVLSPKQASGAALITNPSLAKEIV 130

Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
           +   + L+    V ++T +  DK      +P +     + +T+H R+++      + WE+
Sbjct: 131 KITKEALNFEKPVSVKTRIGFDKIEIDEWIPLILESEPACLTLHLRTKKELSLVPAHWEH 190

Query: 422 ------IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
                 +E   Q +    + GNGD+ +YE  ++       + GVMIGR     PW+FN+
Sbjct: 191 QVLDRVVELRNQISPNTLLVGNGDVETYEQGIDYINQFG-IDGVMIGRAVYGNPWLFNK 248


>UniRef50_Q5KGP0 Cluster: Putative uncharacterized protein; n=3;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 496

 Score = 62.5 bits (145), Expect = 3e-08
 Identities = 61/252 (24%), Positives = 109/252 (43%), Gaps = 24/252 (9%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLL---------KGL----K 287
           I++ NKL L+P+   G+LP R +   +GA +      +  +++          G+    K
Sbjct: 104 INYKNKLVLAPMVRTGSLPMRLLSLYYGAGLVWSPEVVDRAIIGAERSVDPVTGVITYHK 163

Query: 288 QEWALVKRHETEDLFGA-QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG 346
            +  +   H  E  F   QI  +NP +  K AQ +Q+  ++  IDLN GCP       G 
Sbjct: 164 GQGPIFSTHPAEKPFLIFQIGSSNPELAVKAAQTVQQ--DVAGIDLNCGCPKPFSTHAGM 221

Query: 347 GSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHG 406
           G+ ++     L   +R     + +P + K+R  +   +  T  +  ++   G   +TVH 
Sbjct: 222 GAALLSTPELLLDILRALLDSIPLPISCKIR--LLPTQPSTLYLASRILRTGVRNLTVHC 279

Query: 407 RSREARYTKSSDWEYIETCAQAA--TPCPVYGNGDIFSYEDYVEMRK----IAPTVKGVM 460
           R+R+ R  + + WE + +  +        V  NGD   + ++  +R      A     VM
Sbjct: 280 RTRQMRPGERALWERLSSIVELGKRRGISVICNGDGEGWSNWDRIRNETGMCASCADSVM 339

Query: 461 IGRGALIKPWIF 472
           + R A   P +F
Sbjct: 340 LARSAERNPSVF 351


>UniRef50_A7EMF2 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 342

 Score = 62.1 bits (144), Expect = 4e-08
 Identities = 56/228 (24%), Positives = 93/228 (40%), Gaps = 9/228 (3%)

Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309
           +P+     L FR    ++G D+    M L +   + +    +      T     AQ    
Sbjct: 35  APMVRYSKLAFRETVAQYGVDLCWTPMILAKEFNRSVFARDSDFTTSPTSTPTIAQFGVC 94

Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369
           +P  I++   L+     ++ ID+N GCP         G+ +MH+   +   V+ A   L 
Sbjct: 95  SPLEISRSTTLIAPY--INGIDINCGCPQSWACACSIGAALMHKRELVAEMVKEAKSALK 152

Query: 370 IPF-----TVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424
                   TV ++  +++D + T   +  + + G   IT+HGR R    +   + E I+ 
Sbjct: 153 REGYEGKKTVSVKIRIHRDLRDTVDFIKTVQDAGVDFITIHGRMRSTPSSHPVNLEAIK- 211

Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
                T  P   NGDI S     E  +   +V GVM  RG L  P +F
Sbjct: 212 LLNTHTTVPTVSNGDITSLRSAHEHTQ-QTSVSGVMSARGLLSNPALF 258


>UniRef50_A2ACC0 Cluster: Novel protein; n=17; Eumetazoa|Rep: Novel
           protein - Mus musculus (Mouse)
          Length = 194

 Score = 61.3 bits (142), Expect = 7e-08
 Identities = 41/136 (30%), Positives = 71/136 (52%), Gaps = 9/136 (6%)

Query: 296 HETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRL 354
           +  E+L+   +C  +  +I + A L Q+    D IDLN+GCP  +I K+G  G+ +    
Sbjct: 60  YRKENLY-CDVCPEDRPLIVQAALLAQDYC--DAIDLNLGCP-QMIAKRGHYGAFLQEEW 115

Query: 355 PALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR-- 412
             L+  +  A + LS+P T K+R     DK + +     +   G  L+TVHGR++E +  
Sbjct: 116 DLLQRMILLAHERLSVPVTCKIRVFPEIDKTVRY--AQMLEKAGCQLLTVHGRTKEQKGP 173

Query: 413 YTKSSDWEYIETCAQA 428
              ++ WE+I+   +A
Sbjct: 174 MAGTASWEHIKAVRKA 189


>UniRef50_Q4UGK9 Cluster: Putative uncharacterized protein; n=2;
           Theileria|Rep: Putative uncharacterized protein -
           Theileria annulata
          Length = 359

 Score = 61.3 bits (142), Expect = 7e-08
 Identities = 59/232 (25%), Positives = 97/232 (41%), Gaps = 22/232 (9%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETED--LFG 303
           K  ++P+     LPFR +C+ + AD+    M    + +    + +  +  H + D     
Sbjct: 27  KFIVAPMVDQSELPFRLLCRRYSADLAYTPM--LHAKIFSENENYRNIHFHTSSDDKPLI 84

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
           AQ CGN+P      +  ++   ++  ID+N+GCP   I KKG     +   P L T    
Sbjct: 85  AQFCGNDPSAFILASSYIK--NDVSAIDINLGCP-QGIAKKGRYGSFLLEYPQLITK--- 138

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSS--DWEY 421
               +   F +  R  ++         V      G   +TVHGR R    T+ S  DW+ 
Sbjct: 139 GFASVDTKFMLFTRGWLFS--------VQSCQANGCKALTVHGRHRSETKTRISECDWDS 190

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473
           I+   ++    PV  NG I ++ED V+          VM     L  P++F+
Sbjct: 191 IK-IIKSRVNIPVIANGGIETFED-VKRCLDYTGADAVMSSEAILENPYLFS 240


>UniRef50_Q4PAE4 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 766

 Score = 61.3 bits (142), Expect = 7e-08
 Identities = 60/262 (22%), Positives = 116/262 (44%), Gaps = 24/262 (9%)

Query: 234 LPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCG----EMAL--CE------- 280
           +P    T+++ N ++L+P+  +G LP R +  E+GAD+  G    + A+  CE       
Sbjct: 65  IPVCTSTLEYRNGIFLAPMVRIGTLPTRLLSLEYGADLVWGPEIVDRAIIGCERKVNPHT 124

Query: 281 SLLKGLKQEWALVKRHETEDLFGA-QICGNNPYIITKVAQLLQENTELDFIDLNIGCPID 339
            +++ LK    +   H  E  +   Q+   +P++  +  + + +  ++  +DLN GCP  
Sbjct: 125 GVVEYLKDHKQIFSCHPIERPYLVYQLGSADPHLAFQAIKTITQADDVAAVDLNCGCPKP 184

Query: 340 LIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGA 399
                G G+ M+     L  +++   +       V  +  +   ++ T  +V K+   GA
Sbjct: 185 FSTHAGMGANMLSTPILLCNTLKAMRRAAPAHVAVTCKIRLLPTQEKTLELVDKIVRTGA 244

Query: 400 -SLITVHGRSREARYTKSSDW----EYIETCAQAAT----PCPVYGNGDIFSYEDYVEMR 450
              +TVH R+++ R  + +      E ++     AT      PV  NGD++       ++
Sbjct: 245 IECLTVHCRTKDMRPREPALLHRLREIVDHVNSVATEMGRTIPVVCNGDVWDAATVPRIK 304

Query: 451 KIAPTVKGVMIGRGALIKPWIF 472
           ++   V   MI RGA   P  F
Sbjct: 305 ELT-GVTSTMIARGAEANPSCF 325


>UniRef50_Q5SMC7 Cluster: TRNA-dihydrouridine synthase; n=2; Thermus
           thermophilus|Rep: TRNA-dihydrouridine synthase - Thermus
           thermophilus (strain HB8 / ATCC 27634 / DSM 579)
          Length = 342

 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 64/265 (24%), Positives = 124/265 (46%), Gaps = 20/265 (7%)

Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTC-GEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           +L ++P+    +  FR + ++    V    EM + +++L+G  +E  L  R E E     
Sbjct: 5   RLSVAPMVDRTDRHFRFLVRQVSLGVRLYTEMTVDQAVLRG-NRERLLAFRPE-EHPIAL 62

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G++P  + + A++  E    D I+LN+GCP +   + G G+ ++  L  +   ++  
Sbjct: 63  QLAGSDPKSLAEAARI-GEAFGYDEINLNLGCPSEKAQEGGYGACLLLDLARVREILKAM 121

Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTI---VPKMSNWGASLITVHGRSR-EARYTKSS--- 417
            + + +P TVKMR G+ + K+    +   V  M+  G  +  VH RS   A  TK++   
Sbjct: 122 GEAVRVPVTVKMRLGL-EGKETYRGLAQSVEAMAEAGVKVFVVHARSALLALSTKANREI 180

Query: 418 ---DWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
                +++              NG I S E+ +   K    V GVM+GR     P++  E
Sbjct: 181 PPLRHDWVHRLKGDFPQLTFVTNGGIRSLEEALFHLK---RVDGVMLGRAVYEDPFVLEE 237

Query: 475 IKEQKIWDISSK-DRFEILKKYSNY 498
             +++++ +  +  R E+ ++   Y
Sbjct: 238 -ADRRVFGLPRRPSRLEVARRMRAY 261


>UniRef50_Q83D40 Cluster: TIM-barrel protein, yjbN family; n=7;
           Bacteria|Rep: TIM-barrel protein, yjbN family - Coxiella
           burnetii
          Length = 353

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 17/237 (7%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTC-GEMALCESLLKGLKQEWALVKRHETEDLF 302
           N ++ ++P+    +  FR   ++    V    EM    +LLKG  ++W  +     E   
Sbjct: 28  NRRISIAPMMGCTDRHFRMFMRQISRHVLLYTEMVTTGALLKG--KQWRCLDYSPEEHPL 85

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             Q+ G++P  +   A+L +E    D I+LN+GCP   +     G+ ++     +   V 
Sbjct: 86  ALQVGGSDPQSLALCARLAEEKG-FDEINLNVGCPSGRVIAGRFGACLLKEAELVADCVA 144

Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHT--IVPKMSNWGASLITVHGRS--------REAR 412
             S  ++IP +VK RTGV       H    V  ++  G  +  +H R          E R
Sbjct: 145 AMSAEVNIPVSVKTRTGVDDQDSYEHLYHFVKTVAEAGCRIFIIHARKAWLKGLSPAENR 204

Query: 413 YTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKP 469
                 +  +    Q      +  NG I + E   +  +    V GVMIGR A   P
Sbjct: 205 TVPPLAYPMVYQLKQDFPGLEIIINGGIKTIEAINDHLR---EVDGVMIGREAYANP 258


>UniRef50_Q4FQ57 Cluster: Possible tRNA-dihydrouridine synthase;
           n=5; Moraxellaceae|Rep: Possible tRNA-dihydrouridine
           synthase - Psychrobacter arcticum
          Length = 350

 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 12/166 (7%)

Query: 318 AQLLQENT----ELDF--IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL--S 369
           AQL+ EN     EL    ID+N GCP   +    GGS ++     +   +    + +  +
Sbjct: 109 AQLMAENAAHACELGAPAIDINFGCPAKTVNSHRGGSVLLDEPEVMYDIISAVRQAVPAN 168

Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429
           IP + K+R G Y D      I   ++  GA  +T+H R++   Y   + W+ I+  A  +
Sbjct: 169 IPVSAKIRLG-YTDTSRMDDIRGAIAASGADWLTIHARTKTQGYKPPAYWDKIQ--AFNS 225

Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
              PV  NG+I++ E        + T   +M+GRGA+ +P +  ++
Sbjct: 226 LKIPVIANGEIWNSEHAQNCMAQSGTTH-LMLGRGAVTRPDLIAQV 270


>UniRef50_A4RU69 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 345

 Score = 58.4 bits (135), Expect = 5e-07
 Identities = 54/238 (22%), Positives = 96/238 (40%), Gaps = 19/238 (7%)

Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMAL------CESLLKG-------LKQE 289
           +  K   +P+  +  L  R +  E+GAD+  GE  +      C  +L         +  +
Sbjct: 11  YTGKNVCAPMVRISTLATRLLAHEYGADLVYGEELVDKRFMHCRRILNKELGSVDFIDAK 70

Query: 290 WALVKRH--ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGG 347
             L  R   E  +    Q+  ++     K A+L+  +     ID+N+GCP       G G
Sbjct: 71  GTLTFRTVPEERERVVFQVGTSSAASALKSAELVARDVAA--IDVNMGCPKHFSTSGGMG 128

Query: 348 SGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGR 407
           + ++ +   +   +    + L     V  +  + + ++ T  +   + + G S   VHGR
Sbjct: 129 ARLLSQPELVRDILTTLRRNLPSTTHVTCKIRLLESERETAELAKMIESCGVSAFAVHGR 188

Query: 408 SREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465
               R  + + W  I+   + A  CPV  NGD+  YED+  +R         M  RGA
Sbjct: 189 YIPQRPREPAHWNLIKNVVE-AVDCPVIANGDVECYEDFARIR-AQTGAASAMCARGA 244


>UniRef50_Q3IKP0 Cluster: TRNA-dihydrouridine synthase C; n=5;
           Alteromonadales|Rep: TRNA-dihydrouridine synthase C -
           Pseudoalteromonas haloplanktis (strain TAC 125)
          Length = 326

 Score = 57.6 bits (133), Expect = 9e-07
 Identities = 53/203 (26%), Positives = 89/203 (43%), Gaps = 8/203 (3%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTV--KMRTGVYQDKKIT 387
           IDLN GCP   + K  GG+ ++     +   ++     +     V  K+R G + D   +
Sbjct: 92  IDLNFGCPAKTVNKSKGGAVLLKDPEHMYEIIKAVRDAVDSKHQVSAKIRLG-FDDDSNS 150

Query: 388 HTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYV 447
             IV  + + GAS I +H R++   Y   + WE I    +      V  NG+I+   D +
Sbjct: 151 QEIVDAVVSAGASSIAIHARTKRDGYNPPAYWEKIPPLIK-DKDIAVVANGEIWQVADAM 209

Query: 448 EMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFE-ILKKYSNYGLEHWGSD 506
             +K +     +M+GRGAL  P +  +IK     +      +E IL    N  + H  + 
Sbjct: 210 LCQKRSGCT-DLMLGRGALSHPDLAKKIKANINNEHYVGLEWEHILYHLINSAIHHDPAK 268

Query: 507 TQGVESTRRFLLEWLSFLYRYVP 529
            +   ++R    +WL +L R  P
Sbjct: 269 DEKYFASR--TKQWLGYLKRQYP 289


>UniRef50_A5Z3X7 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 326

 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 53/189 (28%), Positives = 88/189 (46%), Gaps = 17/189 (8%)

Query: 305 QICGNNP-YIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV-- 361
           QI  N   Y I    QL++   + + I+LN GCP   +  K  G+G +    A++     
Sbjct: 65  QILANRADYFIKAANQLIELGYDKE-INLNAGCPSGTVVSKNKGAGFLKDTEAMDRFFDE 123

Query: 362 ------RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTK 415
                 +  S+  ++  +VK R G+Y+  +    I+   + +  S + VH R+RE  Y  
Sbjct: 124 TFNWLEKKNSEGHNLSISVKTRIGMYEPDEF-ENILEVYNKYPISQLIVHPRTREQLYKG 182

Query: 416 SSDWEYIETCAQAATPCPVYGNGDIFSYEDYVE-MRKI----APTVKGVMIGRGALIKPW 470
           + + E  +   + +   PV  NGDI + E+Y   + KI       +  +MIGRG +  P 
Sbjct: 183 TPNMEAFKYALENSKN-PVCYNGDINTVENYHRIIEKINDDSEMKIGSIMIGRGLIGNPN 241

Query: 471 IFNEIKEQK 479
           + NEIK  K
Sbjct: 242 LVNEIKGGK 250


>UniRef50_Q4PBU9 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 477

 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 45/195 (23%), Positives = 83/195 (42%), Gaps = 28/195 (14%)

Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363
           AQ   + P      ++L+     +D +DLN GCP    Y++  GS ++ +   +   VR 
Sbjct: 171 AQFASSKPEPFADASELI--GRFVDGVDLNCGCPQPWAYEELLGSYLLRQPETVRDMVRA 228

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
               +   F V ++  +  D ++T  +V    + GAS++ +HGR+R    ++  + + I+
Sbjct: 229 VKARMGSDFCVSVKIRIDPDLRLTDALVRNALHAGASILQIHGRTRWQSSSEPVNLDGIK 288

Query: 424 TCAQAATPC-------------------------PVYGNGDIFSYEDYVEMRKIAPTVKG 458
               AA  C                         P   NGD+++ +D +  R+     +G
Sbjct: 289 FAVDAANACGFRTSWGSKGGAAARFADGGSGGLVPCVANGDVWTLDDAIHYRQ-TTGCRG 347

Query: 459 VMIGRGALIKPWIFN 473
            M  RG L  P +F+
Sbjct: 348 AMSARGLLANPALFS 362


>UniRef50_Q97DM0 Cluster: Predicted TIM-barrel enzyme, nifR3 family;
           n=17; Clostridiales|Rep: Predicted TIM-barrel enzyme,
           nifR3 family - Clostridium acetobutylicum
          Length = 311

 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 36/166 (21%), Positives = 73/166 (43%), Gaps = 8/166 (4%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389
           ++LN+GCP   +  KG G+G + +   L+  +           ++K R G     +  + 
Sbjct: 88  VNLNLGCPSGTVVSKGRGAGFLKKRQELDEFLEKIFSKSPAKISIKTRIGKDSPDEF-YE 146

Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449
           ++   + +    + +H R +   Y    + +  +   + +     Y NGDIF   DY+++
Sbjct: 147 LIKIFNKYPLEELIIHPRIQTDFYNNKPNMKVFKDALELSKSTVCY-NGDIFQSNDYIKL 205

Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKY 495
            +    +  VM+GRG +  P I  +I    + +       E+LKK+
Sbjct: 206 IEEFSNLGVVMLGRGIISNPNIIKKINSNNVLE------KEVLKKF 245


>UniRef50_Q7R1J1 Cluster: GLP_38_15456_16676; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_38_15456_16676 - Giardia lamblia
           ATCC 50803
          Length = 406

 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 7/117 (5%)

Query: 305 QICGNNPYIITKVAQLLQEN---TELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361
           Q+CGNNP      A+LL ++   ++L  +D+N+GCP      KG G  +    P +   +
Sbjct: 118 QLCGNNPSTFRAAAELLHDSPIASQLVALDINLGCPASCASSKGYGFYVAQNWPLVHQII 177

Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGR--SREARYTKS 416
              S     P T K+R     +K I + ++  MS  GAS IT+H R  +R+ ++ ++
Sbjct: 178 SETSSARLFPVTCKIRPLNSIEKTIDYMVLLVMS--GASGITIHMRHTTRQGKHAQA 232


>UniRef50_A1IED4 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep: Putative
           uncharacterized protein - Candidatus Desulfococcus
           oleovorans Hxd3
          Length = 324

 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 2/139 (1%)

Query: 333 NIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVP 392
           N+GCP  ++ KK  G+G++     +   +      +    +VK+R G + D      ++P
Sbjct: 93  NLGCPYPMVAKKYRGAGLLPHTDRIAEFLDTVMSRMKGGLSVKIRLG-WADTTELMGLLP 151

Query: 393 KMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKI 452
            +  +  + + VH R+   RY  + D    E   +  T  PV  NGDI +  D+  +   
Sbjct: 152 VLHRYPLAELIVHPRTGIQRYEGTVDLAAFERVLEN-TGLPVMYNGDIQTVADFAYLSGR 210

Query: 453 APTVKGVMIGRGALIKPWI 471
              V   MIGRGAL  P++
Sbjct: 211 FKAVDRWMIGRGALADPFL 229


>UniRef50_A0EAZ6 Cluster: Chromosome undetermined scaffold_87, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_87,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 346

 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 50/206 (24%), Positives = 89/206 (43%), Gaps = 16/206 (7%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ GN+P  + K AQ+  E    D I+LN+GCP + +     G+ +M     +   ++  
Sbjct: 70  QLGGNDPEKLAKAAQIA-EQAGFDEINLNVGCPSERVQDGAFGACLMKEPHLVAQCMKKM 128

Query: 365 SKLLSIPFTVKMRTGV--YQDKKITHTIVPKMSNWG-ASLITVHGRS--------REARY 413
            + + IP T+K R GV      +     V  +   G  +   +H R          E R 
Sbjct: 129 KEAVKIPCTLKCRLGVDNLDSYEFVRNFVEIVYKEGEVNHFIMHARKAFLKGLNPHENRT 188

Query: 414 TKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473
                ++++    +         NG I   E    + ++ P V G+MIGR A   PW+F+
Sbjct: 189 VPPLKYDWVYQLKKEFPEIKFTLNGGIKCTE---HIDQVLPNVDGIMIGRSAHENPWMFS 245

Query: 474 EIKEQKI-WDISSKDRFEILKKYSNY 498
           +        +  + +R EIL++Y+ +
Sbjct: 246 DFDRLYYGGENQNYNRKEILEQYAEF 271


>UniRef50_UPI0000DAE45A Cluster: hypothetical protein
           Rgryl_01000346; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000346 - Rickettsiella
           grylli
          Length = 330

 Score = 55.2 bits (127), Expect = 5e-06
 Identities = 58/247 (23%), Positives = 109/247 (44%), Gaps = 22/247 (8%)

Query: 260 FRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQ 319
           FR ICK+  A +   EM   +++LK   +E  L+     E     Q+ G     ++K A+
Sbjct: 29  FRLICKK--AQLYT-EMFTAQAILKSPARE-RLLTVDANEKALAIQLGGGIASDLSKAAK 84

Query: 320 LLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTG 379
           ++ E+     I+LN+GCP + +   G G  ++     +  ++     ++ +P TVK R G
Sbjct: 85  IV-ESYGYSEINLNVGCPSEKVQSGGFGVVLLKEPNRVADAIAAMKAVVRLPVTVKTRIG 143

Query: 380 VYQDKKITH--TIVPKMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAA 429
           V  D+   +  + + ++S  G     +H R         +E R     ++ ++    +  
Sbjct: 144 VDNDESYDYLASFIRQVSLAGCDTFIIHARKAWLHGVSPKENREIPPLNYPWVYQIKRDF 203

Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRF 489
               +  NG I   +   +  +    V  VMIGR A   P++F ++       IS +DRF
Sbjct: 204 PHLTIVLNGGITCLKRAYQQLQ---HVDAVMIGRAAWYNPYLFAQLDAL----ISPQDRF 256

Query: 490 EILKKYS 496
            +  ++S
Sbjct: 257 IVPHRFS 263


>UniRef50_Q4FLD8 Cluster: Putative uncharacterized protein; n=2;
           Candidatus Pelagibacter ubique|Rep: Putative
           uncharacterized protein - Pelagibacter ubique
          Length = 330

 Score = 55.2 bits (127), Expect = 5e-06
 Identities = 55/237 (23%), Positives = 111/237 (46%), Gaps = 22/237 (9%)

Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334
           EM + E++ +G K++  L++ +  E     QI G++P ++ +  ++  E+   D I+LN+
Sbjct: 34  EMVVSEAIHRGDKKK--LLEFNINEKPIALQIGGSSPTLLAEATKV-GEDFGYDEINLNL 90

Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSI---PFTVKMRTGV--YQDKKITHT 389
           GCP   + K   G+ +M + P L     C SK+ S+   P T+K R G    +D +  H 
Sbjct: 91  GCPSKKVEKNKFGACLM-KEPNLVAD--CLSKMQSVTKLPVTIKTRIGYDDTEDYENLHR 147

Query: 390 IVPKMSNWGASLITVHGRSR-EARYTKSSD-------WEYIETCAQAATPCPVYGNGDIF 441
            +  + + G     +H R     ++T   +       ++++    +      +  NG I 
Sbjct: 148 FISTLKSTGVKTFIIHARKAILGKFTPKQNLNIPPLKYDFVYRLKKDFPNEEIIINGGIT 207

Query: 442 SYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNY 498
           + +   +M+     V GVMIGR A   P++  +I+     + +   R +++++   Y
Sbjct: 208 TTD---QMKDHLDKVDGVMIGRAAYHTPYLLADIERDIFNNENVPSRQDVIEQLLPY 261


>UniRef50_A2DHB4 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 312

 Score = 55.2 bits (127), Expect = 5e-06
 Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 16/214 (7%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALV--KRHETEDLFGA 304
           ++L+P+  V +  FR++C++ G  +           +   KQ    V     + E     
Sbjct: 15  IFLAPMADVNDYSFRKLCRQNGVSLCWTGFINAHHWVTRTKQRDRDVWFTTRDNEKNLVV 74

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM----HRLPALETS 360
           Q+ G+N   +   A+ + EN   D I+LN GC      + G G  ++    HR  AL   
Sbjct: 75  QLLGSNLEELVSCAKDV-ENF-CDMIELNCGCTHCFASRSGCGFFLIDTQKHRDSAL-IL 131

Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKI-----THTIVPKMSNWGASLITVHGRSREARYTK 415
           ++   K ++ P ++K+R  +  D  +     T      +   G SLITVH R+++A    
Sbjct: 132 IQNLIKSINKPVSIKIRL-ISDDNSVPSLERTVKFAQDLERVGVSLITVHARTQQADKKG 190

Query: 416 SSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449
             D++ I+   QA +  PV  NG I S E   E+
Sbjct: 191 DVDYDAIKAVVQAVS-VPVIANGGISSLEQAQEI 223


>UniRef50_Q7R9R0 Cluster: Uncharacterized protein family UPF0034,
           putative; n=7; Plasmodium|Rep: Uncharacterized protein
           family UPF0034, putative - Plasmodium yoelii yoelii
          Length = 531

 Score = 54.4 bits (125), Expect = 8e-06
 Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 5/165 (3%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCG-EMALCESLLKGLKQEWALVKRHETEDLFGAQ 305
           + ++P+  V N  FR + +     V    EM +  +LL  +      +  ++ E     Q
Sbjct: 154 IQVAPMINVTNRHFRALVRIISKKVQLWTEMIVDNTLLYNINNLEEHLGFNKNEHPIVCQ 213

Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRCA 364
           + G++P  +++ A +L E    D I++N+GCP   +  KG  G+ +M     ++  V   
Sbjct: 214 LGGSDPTSLSEAA-ILVEQAGYDEININVGCPSTKVANKGAFGAYLMKNPQLVKNIVYEI 272

Query: 365 SKLLSIPFTVKMRTGV--YQDKKITHTIVPKMSNWGASLITVHGR 407
            K + IP TVK+RTGV          + +  +S+ G     +H R
Sbjct: 273 KKKVQIPVTVKIRTGVDNLDSFSFLRSFIETVSSAGCDHFIIHSR 317


>UniRef50_A5WG83 Cluster: TIM-barrel protein, yjbN family; n=4;
           Moraxellaceae|Rep: TIM-barrel protein, yjbN family -
           Psychrobacter sp. PRwf-1
          Length = 348

 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 69/286 (24%), Positives = 113/286 (39%), Gaps = 20/286 (6%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTC-GEMALCESLLKGLKQEWALVKRHETEDLF 302
           N +L ++P+       +R   + F        EM    ++L+G      L++    E   
Sbjct: 20  NKRLSVAPMIDWTTTDYRFFARLFNPHTYLYTEMISTSAILQGKTDR--LLRYDTLEHPL 77

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             Q+ G +   +T+ A   Q+    + +++N+GCP D +     G+ +M     +   VR
Sbjct: 78  VLQLGGADISEMTQCAVEAQKRG-FNEVNINVGCPSDRVQHNKIGACLMAEPDTVAALVR 136

Query: 363 CASKLLSIPFTVKMRTGV--YQDKKITHTIVPKMSNWGASLITVHGR--------SREAR 412
                + IP TVK R G+  +   +     V   +  G     VH R         +E R
Sbjct: 137 NMQAHVDIPVTVKHRIGIDEHDSYEFMQDFVSASAEAGCQRFIVHARIAWLNGLSPKENR 196

Query: 413 YTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
                 +E +    QA     +  NG I S E   +++     V GVMIGR A   P+I 
Sbjct: 197 EIPPLRYEDVYRLKQAFPELHIEINGGIDSIE---QIKAHLQQVDGVMIGRAAYHNPYIL 253

Query: 473 NEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLL 518
            E      W  ++  R +IL K   Y LE   +  + + S  R  L
Sbjct: 254 AE--AMSFWGEAAPSRAQILTKLYPY-LEQQVAKGEPLPSLARHFL 296


>UniRef50_Q04VP3 Cluster: TRNA-dihydrouridine synthase; n=4;
           Leptospira|Rep: TRNA-dihydrouridine synthase -
           Leptospira borgpetersenii serovar Hardjo-bovis (strain
           JB197)
          Length = 339

 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 52/205 (25%), Positives = 88/205 (42%), Gaps = 15/205 (7%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G+NP  + + +++  E+     I+LN+GCP D + +   G+ +M     +   V   
Sbjct: 71  QLGGDNPKALAESSKI-GEDYGYSEINLNVGCPSDRVREGNFGACLMETPERVAELVCAM 129

Query: 365 SKLLSIPFTVKMRTGVYQDKKITH--TIVPKMSNWGASLITVHGR--------SREARYT 414
              +SIP TVK R G+   + +      +  +   G     VH R          + R  
Sbjct: 130 DGNVSIPVTVKCRIGISGKETLEDLCRFIECVRQAGVRRFIVHARIAILGGLSPAQNRQI 189

Query: 415 KSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
               + ++E+  +      +  NG I       EM+    T  GVMIGR A   P++F+E
Sbjct: 190 PPLRYAHVESLKKEFPDLLIEINGGI---RTLAEMQDRLKTNDGVMIGRAAYETPYLFSE 246

Query: 475 IKEQKIWDIS-SKDRFEILKKYSNY 498
           +      D S S  R E+L +  +Y
Sbjct: 247 VDSLFFHDNSPSLSRREVLLRMRDY 271


>UniRef50_Q4Q391 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 493

 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 61/251 (24%), Positives = 103/251 (41%), Gaps = 31/251 (12%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306
           L  +P+       FR++C+ +G  V+   M + ES +K      A   R+E E+   AQ+
Sbjct: 98  LIQAPMVRCSRPAFRQVCRAWGTRVSYTHMLMAESFVKSPHARHAEFARYEGENRLVAQL 157

Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM---HRLPALETSVR- 362
              +     + A LL+     D IDLN GCP     K+G G+ ++    R+  +  S+R 
Sbjct: 158 AAKSGPAAAQAALLLR--PYCDGIDLNCGCPQRWAMKEGIGAALLDQPERVADMVRSIRN 215

Query: 363 --------------------CASKLLS-IPFTVKMRTGVYQDKKITHTIVPKMSNWGASL 401
                               C S +   +P  VKMR  +  D + +     +    G S 
Sbjct: 216 AMPDGSTAPMIVGNGGEYSSCTSAVPPFLPCVVKMR--IKDDLRRSVDFARQCEAAGVSW 273

Query: 402 ITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMI 461
           +TVHGR+     + +  +E ++   +  +  PV  NG +      +E   +     G+M 
Sbjct: 274 LTVHGRTPTCHSSTAVQFEAVKLIRENLS-VPVVLNGGVTDVSTAME-AALRTGCGGLMS 331

Query: 462 GRGALIKPWIF 472
             G L  P +F
Sbjct: 332 ANGLLDNPAMF 342


>UniRef50_Q9PGB5 Cluster: tRNA-dihydrouridine synthase A; n=8;
           Proteobacteria|Rep: tRNA-dihydrouridine synthase A -
           Xylella fastidiosa
          Length = 340

 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 53/211 (25%), Positives = 95/211 (45%), Gaps = 17/211 (8%)

Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334
           EM   ++++ G ++   L+     E     Q+ G+ P ++ K A++  +    + I+LN 
Sbjct: 47  EMVHAKAVIYGDRER--LLGFASVEQPVALQLGGSEPALLAKAARIAVDWGYSE-INLNC 103

Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITH--TIVP 392
           GCP D +     G+ +M     +   V   + ++S+P TVK R GV +D         V 
Sbjct: 104 GCPSDRVQAGSFGARLMREPALVADCVAAMAAVVSVPVTVKCRLGVNEDDDYGRFAKFVD 163

Query: 393 KMSNWGAS-LITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSY 443
            +S   +S +I VH R+        +E R      ++++    +      V  NG I S 
Sbjct: 164 WVSRASSSRMIVVHARNAWLQGLSPKENREIPPLRYDWVYRLKRERPELAVVLNGGITSV 223

Query: 444 EDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
           E  ++   +   V GVM+GR A   P+I ++
Sbjct: 224 EAGLDHLLM---VDGVMLGRAAYQDPYILHQ 251


>UniRef50_A2EN54 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 321

 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 62/256 (24%), Positives = 108/256 (42%), Gaps = 16/256 (6%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308
           L+P+  +G++ FR +C   G DV    M       +        ++  E +     QI G
Sbjct: 17  LAPMVEMGDIAFRILCHRHGCDVCWTGMINGSQWNRSKTYRQQQIEYSEEDRPLVIQISG 76

Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRCASKL 367
           +    +   A+ + E      ID+N+GC    + K+G  G  M+      +  V     +
Sbjct: 77  SIDVDLLTTAKSMSEFGVP--IDINLGC-CQKVAKRGEYGYFMVDSEQKRQNVVNLIKSI 133

Query: 368 ---LSIPFTVKMR-----TGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419
              +++P  VK+R     +G+     IT      +   GASLIT+HGRS         + 
Sbjct: 134 PSEITVPLYVKIRALTDESGI-PSIPITVDFAKHLEEAGASLITIHGRSAAQDKHGPLNK 192

Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQK 479
           E ++   QA +  PV  NG I S +D   M +    +   M  +  L+ P +F++   Q 
Sbjct: 193 ELVKAVVQAVS-IPVIVNGGINSLDDARNMIRETGAI-AAMSAQSLLMDPTLFDKNGRQP 250

Query: 480 IWDISSKDRFEILKKY 495
              + + +  +I +KY
Sbjct: 251 N-TVFALEYLDIFEKY 265


>UniRef50_Q5ZVH8 Cluster: Zinc binding TIM barrel protein, YjbN
           family; n=4; Legionella pneumophila|Rep: Zinc binding
           TIM barrel protein, YjbN family - Legionella pneumophila
           subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 /
           DSM 7513)
          Length = 334

 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 57/264 (21%), Positives = 108/264 (40%), Gaps = 16/264 (6%)

Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304
           +KL ++P+    N PFR + +    +            ++    + AL   +  E     
Sbjct: 11  SKLSIAPMIDWTNSPFRTLMRLLAPNALLYTEMQTTGAVQN-NPDRALYF-NSVEHPLAI 68

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G +   + K A ++ E    + I+LN+GCP D +     G+ +M     +   +R  
Sbjct: 69  QLGGADKSALVKCA-IIAEQKGFNEINLNLGCPSDKVQAGRFGACLMKEPEHVADCIRAI 127

Query: 365 SKLLSIPFTVKMRTGV-YQDK-KITHTIVPKMSNWGASLITVHGRS--------REARYT 414
            +++ IP T K R G+  QD  +   +    +   G   + +H R         ++ R  
Sbjct: 128 KQVVGIPVTAKTRIGIDNQDSYEFFRSFSLHLVEAGCDKLIIHARKAWLNGLNPKQNRTI 187

Query: 415 KSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
              +++Y+    +      +  NG+I + E   E+      V GVM+GR A   P+   E
Sbjct: 188 PPVNYDYVYELKKEIPHIFITINGNILTVE---EINNHLKHVDGVMLGRLACDNPYQIAE 244

Query: 475 IKEQKIWDISSKDRFEILKKYSNY 498
           I +    +     R ++L  Y +Y
Sbjct: 245 IHQALYPEFIKIKRSQLLMNYLDY 268


>UniRef50_A6GGZ7 Cluster: Putative uncharacterized protein; n=2;
           Bacteria|Rep: Putative uncharacterized protein -
           Plesiocystis pacifica SIR-1
          Length = 362

 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 49/214 (22%), Positives = 90/214 (42%), Gaps = 16/214 (7%)

Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334
           EM  C ++L G ++   ++  H +E     Q+ G++P  +   A++  E    D +++N+
Sbjct: 52  EMVTCPAVLHGDREH--ILGYHPSEHPLALQLGGDDPEALAACARIAAE-LGYDEVNINV 108

Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTI--VP 392
           GCP D +     G  +M     +   V    + + +P TVK R GV +  +    +  V 
Sbjct: 109 GCPSDRVQSGNFGVCLMKDPARVRDCVVAMREAVELPVTVKHRIGVDELDRYEDMLHFVD 168

Query: 393 KMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444
            ++     L TVH R         ++ R      +  +   A+      V  NG   + +
Sbjct: 169 VVAAAEPDLFTVHARKAWLQGLSPKQNRNVPPLRYAEVHRLARERPGVFVEINGGFKTAD 228

Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478
              E  +    V  VM+GR A   PW+F  + ++
Sbjct: 229 AIAEQLE---RVDAVMLGRAAWDDPWLFAAVDQR 259


>UniRef50_A1RNI1 Cluster: TIM-barrel protein, yjbN family; n=30;
           Bacteria|Rep: TIM-barrel protein, yjbN family -
           Shewanella sp. (strain W3-18-1)
          Length = 343

 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 46/192 (23%), Positives = 84/192 (43%), Gaps = 14/192 (7%)

Query: 296 HETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLP 355
           ++ E     Q+ G+NP  + + A+L  E    D ++LN+GCP D +     G+ +M    
Sbjct: 72  NQEEHPLALQLGGSNPQDLARCAKLAAERG-YDEVNLNVGCPSDRVQNGRFGACLMAEPE 130

Query: 356 ALETSVRCASKLLSIPFTVKMRTGV-YQDK-KITHTIVPKMSNWGASLITVHGRS----- 408
            +   V    +++ IP TVK R G+  QD  +     +  ++  G +  T+H R      
Sbjct: 131 LVAECVDAMKQVVDIPVTVKTRIGIDEQDSYEFLTYFIDIVNAKGCTDFTIHARKAWLQG 190

Query: 409 ---REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465
              +E R     D+E +    +      +  NG + + E   + +     + GVM+GR A
Sbjct: 191 LSPKENREIPPLDYERVYQLKRDYPVLNISINGGVTTLE---QAQGHLAQLDGVMMGREA 247

Query: 466 LIKPWIFNEIKE 477
              P+I   + +
Sbjct: 248 YQNPYILARVDQ 259


>UniRef50_Q6BX60 Cluster: Debaryomyces hansenii chromosome B of
           strain CBS767 of Debaryomyces hansenii; n=1;
           Debaryomyces hansenii|Rep: Debaryomyces hansenii
           chromosome B of strain CBS767 of Debaryomyces hansenii -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 374

 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 60/257 (23%), Positives = 109/257 (42%), Gaps = 26/257 (10%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGAD------VTCGEMALCESLLKG-------LK 287
           ++++ KL L+P+   G +P R +   +GAD      +   ++  CE ++         L 
Sbjct: 2   VEYSGKLALAPMVRSGEIPTRLMALRYGADLVWTPEIVDKKLIKCERVINDDLGTVDFLD 61

Query: 288 QEWALVKRHETEDLFGA---QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKK 344
               +V R    +  G    QI   +P +  + A+++ +  ++D IDLN GCP       
Sbjct: 62  PNKKVVFRTYPAEELGKLIFQIGSADPELAVQAAKIVAQ--DVDGIDLNCGCPKPFSTHS 119

Query: 345 GGGSGMMHRLPALETSVRC----ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGAS 400
           G G+ ++     LE  +R       K+  IP + K+R     D   +  ++ ++   G S
Sbjct: 120 GMGAALLTTPDLLELILRNLVSEVGKVYDIPISAKIRLLDDTDVTPSLELIDRLCKTGIS 179

Query: 401 LITVHGRSREARYTKSSDWEYIETCAQA--ATPCPVYGNGDIFSYEDY-VEMRKIAPTVK 457
            +T+H R+   R   +   +++ +      A       NG I S  ++ +  RK    V 
Sbjct: 180 NLTLHCRTPRMRNRDTPVRDFLPSIIDTVHANNVSFIINGSIRSRREFHLLQRKYGEKVG 239

Query: 458 GVMIGRGALIKPWIFNE 474
           G MI   A   P +F E
Sbjct: 240 G-MIAESAESNPTVFAE 255


>UniRef50_A6RW05 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 278

 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 42/145 (28%), Positives = 59/145 (40%), Gaps = 11/145 (7%)

Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389
           +D+N GCP         G+ +MH+   +   V+ A   L        R G    K +  T
Sbjct: 63  VDINCGCPQSWACACSIGAALMHKRELVAEMVKEAKSALK-------RDGFEGKKTVRET 115

Query: 390 I--VPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYV 447
           I  +  + + G   IT+HGR R    +   + E I+      T  P   NGDIF+  D  
Sbjct: 116 IDFINTVQDAGVDFITIHGRMRSTPSSHPVNLEAIKLLTTHTT-VPTLSNGDIFTLSDAF 174

Query: 448 EMRKIAPTVKGVMIGRGALIKPWIF 472
                   V GVM  RG L  P +F
Sbjct: 175 H-HTSHTGVSGVMSARGLLENPALF 198


>UniRef50_O51243 Cluster: Putative uncharacterized protein BB0225;
           n=3; Borrelia burgdorferi group|Rep: Putative
           uncharacterized protein BB0225 - Borrelia burgdorferi
           (Lyme disease spirochete)
          Length = 335

 Score = 51.2 bits (117), Expect = 8e-05
 Identities = 61/280 (21%), Positives = 118/280 (42%), Gaps = 30/280 (10%)

Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTC-GEMALCESLLKGLKQEWALVKRHETEDLF 302
           N K+ ++P+  + +  FR + +     VT    M   +S++ G  ++  +VK++  E   
Sbjct: 4   NRKISIAPMVNITDEHFRYLIRLLSKKVTLYTPMISAKSIIMGDVKK--IVKQNPLESPI 61

Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362
             QI  N+     K  Q+L+++   D  +LN+GCP   I     G+ +M     +   ++
Sbjct: 62  AIQIATNSKNDALKAIQILEKHFNFDEYNLNVGCPSLKIQNANCGACLMGNANQVGEILK 121

Query: 363 CASKLLSIPFTVKMRTGV------YQDKKITH--TIVPKMSNWGASLITVHGR------- 407
              +  + P ++K R G+      Y+++  +     V  +S++G     VH R       
Sbjct: 122 TMKENTNKPISIKHRLGIRPLSSDYKNESYSEVKNFVKIISDFGIKNFIVHARIAILKGF 181

Query: 408 -SREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGAL 466
             +  R       E++    +      +  NG I + E   +++K    V  VMIGR A 
Sbjct: 182 SPKNNRNIPKLRHEFVYKLKKENKNLFIEINGGINNSE---QIKKHLSFVDSVMIGRSAF 238

Query: 467 IKPWIFNEIKEQKIWD----ISSKD----RFEILKKYSNY 498
             P+       + + +    ++ KD      E +K+Y NY
Sbjct: 239 ENPYFIANASREFLNETDEILTRKDILMQMVEYIKEYENY 278


>UniRef50_Q0VPD7 Cluster: TIM-barrel protein, yjbN family; n=4;
           Bacteria|Rep: TIM-barrel protein, yjbN family -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 348

 Score = 51.2 bits (117), Expect = 8e-05
 Identities = 48/210 (22%), Positives = 90/210 (42%), Gaps = 16/210 (7%)

Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334
           EM + +++L G +  +  +  ++ E     Q+ G++P  + +  ++  +    D I+LN+
Sbjct: 63  EMVVAQAILHGDRDRF--LDFNDEEHPVALQLGGSDPQQLAQATRIAGDYG-YDEINLNV 119

Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGV--YQDKKITHTIVP 392
           GCP D + +   G+ +M     +   V      +++P TVK R G+    D    +  V 
Sbjct: 120 GCPSDRVQQGKIGAILMAEPELVARCVEAMQAEVTVPVTVKTRIGIDDQDDYDFLYRFVD 179

Query: 393 KMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444
           +M   G + +T+H R         +E R      ++       A     +  NG + +  
Sbjct: 180 RMEASGCTSLTIHARKAILSGLSPKENRDIPPLIYQRAYAIKHAFPHIEIILNGGVKTLN 239

Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
              E+ +    V GVMIGR A   P+   E
Sbjct: 240 ---EVHEHMGEVDGVMIGREAYQNPYFLAE 266


>UniRef50_A7DKP5 Cluster: Dihydrouridine synthase, DuS; n=2;
           Methylobacterium extorquens PA1|Rep: Dihydrouridine
           synthase, DuS - Methylobacterium extorquens PA1
          Length = 354

 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 48/187 (25%), Positives = 77/187 (41%), Gaps = 14/187 (7%)

Query: 299 EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALE 358
           E     Q+ G+NP  +   A++  +    + I+LN+GCP D +     G+ +M     + 
Sbjct: 81  EQPLAVQLGGSNPDDLAAAARIAADFGYAE-INLNVGCPSDRVQDGRFGACLMREPGLVG 139

Query: 359 TSVRCASKLLSIPFTVKMRTGV-YQD-KKITHTIVPKMSNWGASLITVHGRS-------- 408
             V      + +P TVK R GV  QD ++    +   +   G   + VH R         
Sbjct: 140 ACVAALKAAVPVPVTVKCRLGVDDQDIEEALDAVADAVVAAGGDGLVVHARKAWLKGLSP 199

Query: 409 REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIK 468
           RE R     D+  +    +A    P+  NG I    D    +     V GVMIGR A  +
Sbjct: 200 RENRDVPPLDYGRVARLKRAHPDLPIAVNGGI---ADIAAAKARLGEVDGVMIGRAAYTE 256

Query: 469 PWIFNEI 475
           P +  ++
Sbjct: 257 PALLLDV 263


>UniRef50_Q6C002 Cluster: Yarrowia lipolytica chromosome F of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome F of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 394

 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 60/287 (20%), Positives = 120/287 (41%), Gaps = 35/287 (12%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLL----------------- 283
           + +  KL L+P+   G  P R +  ++GAD+      + + +L                 
Sbjct: 2   VSYAGKLVLAPMVRSGEFPTRLLSIKYGADLVWSPEIVDKKMLECTREWNEKTKTVDFTV 61

Query: 284 ----KGLKQEWALVKR-HETE-DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCP 337
               KG  ++ A++ R  E E D    Q+   NP I     +++ +  ++  IDLN GCP
Sbjct: 62  SQQGKGNTEKKAIIFRTSEAERDKIIFQVGSANPEIAVAACKMVAK--DVAGIDLNCGCP 119

Query: 338 IDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPF--TVKMRTGVYQDKKITHTIVPKMS 395
                  G G+ ++     L   +    K +  PF  ++ ++  + + ++ T  +V +++
Sbjct: 120 KHFSMHAGMGAALLKTPDKLVAILEALVKEVGEPFNVSISVKIRLLETEEKTLELVDRLA 179

Query: 396 NWGASLITVHGRSREAR----YTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRK 451
             G   +T+H R+   R      + +  +  E C +    C V  NGD+    +  ++++
Sbjct: 180 QTGVKNLTIHCRTTPMRPREPVIRDTLAKVAEVCHKHGITCLV--NGDVEGRHELADLQE 237

Query: 452 IAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNY 498
               + G MI R A      F   +    W   +K+  +I ++Y N+
Sbjct: 238 -KYGIDGAMIARAAEANASCF-RAEGMLPWQQVTKEYLDICREYDNF 282


>UniRef50_A2EF32 Cluster: Dihydrouridine synthase, putative; n=1;
           Trichomonas vaginalis G3|Rep: Dihydrouridine synthase,
           putative - Trichomonas vaginalis G3
          Length = 318

 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 54/232 (23%), Positives = 89/232 (38%), Gaps = 9/232 (3%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308
           L+P+  + +L +R + +  G  V    M       +G   +         +    AQI G
Sbjct: 22  LAPMAEISDLSWRMLIRNHGVKVCWTGMLNAHQWSQGSGYQNKFFNTCPEDHPLIAQIAG 81

Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL- 367
           +N      VA         D +D+N+GC   +  +   G  M+      E ++    +L 
Sbjct: 82  SNEDQDLIVAAAKDLAKYADGVDVNLGCTQKIASRSEYGYFMVDNCQKREKTLELFRRLC 141

Query: 368 --LSIPFTVKMRTGVYQD----KKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421
             ++ P   K+R  +       +KIT     K+   G SL+ VHGR+           E 
Sbjct: 142 KEVNCPICAKIRIFIDDSGEVSEKITIDFAKKLEEAGVSLLQVHGRAEHRNKQADVYNEI 201

Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473
           I+   QA    PV  NG I + ED  +  +      GV + +  L  P  F+
Sbjct: 202 IKHIVQAVN-IPVVANGGINTVEDAHKFME-ETGAAGVSVAQALLKDPTAFD 251


>UniRef50_A6RVN2 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 1174

 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 35/112 (31%), Positives = 59/112 (52%), Gaps = 6/112 (5%)

Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWEYIE 423
           K L +P T K+R  +   ++ T      + + GAS++TVHGR+RE +  K+  ++WE + 
Sbjct: 790 KELDVPVTAKIR--ILDTREKTLDYAKMVISAGASILTVHGRTREMKGHKTGLANWEMLR 847

Query: 424 TCAQA-ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474
              ++      ++ NG+I + ED  +  K A    GVM   G L  P IF++
Sbjct: 848 FLRESLPKEVVLFVNGNILAREDIDDCLK-ATGADGVMSAEGNLYDPTIFSD 898


>UniRef50_A6U9Y2 Cluster: Dihydrouridine synthase DuS; n=2;
           Sinorhizobium|Rep: Dihydrouridine synthase DuS -
           Sinorhizobium medicae WSM419
          Length = 385

 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 41/136 (30%), Positives = 68/136 (50%), Gaps = 7/136 (5%)

Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334
           EM + +++L+G + +  L+    +E     Q+ GN+P  + + A++  E    D I++N+
Sbjct: 51  EMIVADAVLRGDRAK--LLGHDASEHPVALQLGGNDPVKMAEAARI-GEAYGYDEINMNV 107

Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASK-LLSIPFTVKMRTGV-YQDKKIT-HTIV 391
           GCP D +     G+ +M   PAL      A K  + IP TVK R GV  QD ++    +V
Sbjct: 108 GCPSDRVQSGTFGACLMQE-PALVADCIAAMKAAVEIPVTVKCRIGVDDQDPEVALRDLV 166

Query: 392 PKMSNWGASLITVHGR 407
               + G   + VH R
Sbjct: 167 KCAKDAGTDGVWVHAR 182


>UniRef50_Q7R3H4 Cluster: GLP_158_49916_51304; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_158_49916_51304 - Giardia lamblia
           ATCC 50803
          Length = 462

 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 49/221 (22%), Positives = 98/221 (44%), Gaps = 17/221 (7%)

Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALV---KRHETEDL-FGA 304
           ++P+     LP+R + + +G ++    M    +L+   K    LV   K  E+ D     
Sbjct: 21  IAPMVDGSELPYRLLTRRYGVELAWTPMHSTNTLVTSSKAMTQLVDELKHGESIDRPLVL 80

Query: 305 QICGNNPYIITKVAQLLQENTE---LDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361
           Q+ GNNP         L +       D ++LN+GCP  +  +   G+ +M  L   E  +
Sbjct: 81  QLSGNNPSNFELAYNTLVQMGAGCCFDVVELNMGCPQAVALRGKYGAYLMGHLDLAEEIL 140

Query: 362 R---CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS-- 416
           R     +    +   V ++T +    K T  +  ++ + G ++ T+HGR+R  R   +  
Sbjct: 141 RTLVAVTARSGLGHKVAVKTRLDISDKDTVKMCLRLCSTGIAMFTLHGRTRLQRTGSAVG 200

Query: 417 -SDWEYIETC---AQAATPCPV-YGNGDIFSYEDYVEMRKI 452
             DW+ + +     +A+ P  + + NG +++ E +  +R +
Sbjct: 201 LPDWQALASILNNLRASYPHLIFFANGGVWNLETHEHLRSL 241


>UniRef50_A5GPV9 Cluster: TRNA-dihydrouridine synthase A; n=21;
           Cyanobacteria|Rep: TRNA-dihydrouridine synthase A -
           Synechococcus sp. (strain RCC307)
          Length = 335

 Score = 49.2 bits (112), Expect = 3e-04
 Identities = 56/243 (23%), Positives = 100/243 (41%), Gaps = 19/243 (7%)

Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334
           EM + ++L  G +Q+  L+     E     Q+ G++P ++ + A+L  E    D I+LN+
Sbjct: 45  EMVVAQALHHG-RQD-TLLGFDPLEKPIALQLGGDDPALLAEAAELA-ERWGYDEINLNV 101

Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTI--VP 392
           GCP   + K   G+ +M     +   V        +P TVK R G+ +       +  V 
Sbjct: 102 GCPSPKVKKGRFGACLMAEPQQVARCVEAMGAACRLPVTVKHRIGIDERDSYDELLDFVD 161

Query: 393 KMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444
            ++  G     VH R         ++ R      ++ +    +      V  NG +   E
Sbjct: 162 TVAAAGCQRFAVHARKAWLEGLDPKQNRTVPPLRYDLVHALKRDRPALIVELNGGL---E 218

Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSK--DRFEILKKYSNYGLEH 502
                ++    V GVM+GR A   P  +N + ++   D ++      E+L+    +  EH
Sbjct: 219 SLSACQEQLHAVDGVMVGRAAYAHPLQWNRVDQEIFGDSNATPIKASEVLQGVLPHA-EH 277

Query: 503 WGS 505
           W S
Sbjct: 278 WCS 280


>UniRef50_Q7UBC5 Cluster: tRNA-dihydrouridine synthase A; n=231;
           Bacteria|Rep: tRNA-dihydrouridine synthase A - Shigella
           flexneri
          Length = 330

 Score = 49.2 bits (112), Expect = 3e-04
 Identities = 53/202 (26%), Positives = 87/202 (43%), Gaps = 16/202 (7%)

Query: 297 ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPA 356
           E E     Q+ G++P  + + A+L  E    D I+LN+GCP D +     G+ +M     
Sbjct: 61  EEEHPVALQLGGSDPAALAQCAKLA-EARGYDEINLNVGCPSDRVQNGMFGACLMGNAQL 119

Query: 357 LETSVRCASKLLSIPFTVKMRTGV-YQDK-KITHTIVPKMSNWG-ASLITVHGRS----- 408
           +   V+    ++SIP TVK R G+  QD  +     +  +S  G   +  +H R      
Sbjct: 120 VADCVKAMRDVVSIPVTVKTRIGIDDQDSYEFLCDFINTVSGKGECEMFIIHARKAWLSG 179

Query: 409 ---REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465
              +E R     D+  +    +      +  NG I S E   E +     + GVM+GR A
Sbjct: 180 LSPKENREIPPLDYPRVYQLKRDFPHLTMSINGGIKSLE---EAKAHLQHMDGVMVGREA 236

Query: 466 LIKPWIFNEIKEQKIWDISSKD 487
              P I   + +++I+  S  D
Sbjct: 237 YQNPGILAAV-DREIFGSSDTD 257


>UniRef50_A7AWB5 Cluster: Dihydrouridine synthase (Dus) domain
           containing protein; n=1; Babesia bovis|Rep:
           Dihydrouridine synthase (Dus) domain containing protein
           - Babesia bovis
          Length = 362

 Score = 47.2 bits (107), Expect = 0.001
 Identities = 54/209 (25%), Positives = 89/209 (42%), Gaps = 18/209 (8%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG-GGSGMMHRLPALETSVRC 363
           Q+ GNN   ++K   +       +F +LN+GCP   +  KG  G+ +M+  P +   V+ 
Sbjct: 78  QLGGNNLDSLSKAGNIALGYGYTEF-NLNVGCPSTRVSGKGCFGAALMNDAPLVGRIVKH 136

Query: 364 ASKLLSIPFTVKMRTGV-YQDK-KITHTIVPKMSNWGASLITVHGRS--------REARY 413
               L  P TVK R GV + D  +     +  +++ G +   VH R         R+ R 
Sbjct: 137 LRSELGTPVTVKHRLGVDHNDSYEFVRDFISTVADQGCTDFIVHARKAWLNGINPRKNRS 196

Query: 414 TKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPW--- 470
               D E +    Q      +  NG I S E+      ++  V GVM+GR A   P    
Sbjct: 197 IPPLDHERVYRLCQEFPNLNISINGGIKSLEEI--KYALSRGVYGVMVGRMAYENPCGLV 254

Query: 471 -IFNEIKEQKIWDISSKDRFEILKKYSNY 498
            +  +I  +     + K R  +L+ Y+N+
Sbjct: 255 RVDTDIYGEATNPATCKTRRILLETYANF 283


>UniRef50_A4SY29 Cluster: Dihydrouridine synthase, DuS; n=1;
           Polynucleobacter sp. QLW-P1DMWA-1|Rep: Dihydrouridine
           synthase, DuS - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 347

 Score = 46.4 bits (105), Expect = 0.002
 Identities = 30/112 (26%), Positives = 55/112 (49%), Gaps = 9/112 (8%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           Q+ G+ P  + + A+L Q+    D IDLN GCP + + +   G+ +M     +   V+  
Sbjct: 53  QLGGSEPNDLARSAELAQQ-WGYDEIDLNCGCPSERVQRGAFGACLMAEPKLVADCVKAM 111

Query: 365 SKLLSIPFTVKMRTGV--------YQDKKITHTIVPKMSNWGASLITVHGRS 408
              + IP +VK R G+         +D +     +  +++ GAS +T+H R+
Sbjct: 112 QNAVDIPISVKHRLGLDSMDAANSEKDYQFALDFIMAVADAGASQVTIHARN 163


>UniRef50_A3AVU4 Cluster: Putative uncharacterized protein; n=1;
           Oryza sativa (japonica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 190

 Score = 46.0 bits (104), Expect = 0.003
 Identities = 19/44 (43%), Positives = 29/44 (65%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK 284
           +++ +KL L+P+  VG LPFR +  E+GAD+T GE  +    LK
Sbjct: 1   MEYRDKLVLAPMVRVGTLPFRLLAAEYGADITYGEEIIDHKFLK 44



 Score = 37.1 bits (82), Expect = 1.3
 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 1/45 (2%)

Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
           +A   PV  NGD+F YED+  + K A     VM+ RGA+    IF
Sbjct: 70  SALSIPVIANGDVFEYEDFKRI-KDATGAASVMVARGAMWNASIF 113


>UniRef50_P96192 Cluster: tRNA-dihydrouridine synthase C; n=1;
           Azotobacter vinelandii|Rep: tRNA-dihydrouridine synthase
           C - Azotobacter vinelandii
          Length = 309

 Score = 45.6 bits (103), Expect = 0.004
 Identities = 44/172 (25%), Positives = 74/172 (43%), Gaps = 7/172 (4%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRC 363
           Q+ G++P  + + A L  E      IDLN GCP      +G  G     R   + +S RC
Sbjct: 68  QLLGSDPACLAENAALAAE-LGAPAIDLNFGCPAKTSTARGADGCCSTSRNCCMPSSARC 126

Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423
           A          +   GV +  +    +   +   G + + VH R++   Y   + WE++ 
Sbjct: 127 AGPCRRCAGDRQDAPGV-RPARGRPGVRRALVEGGVAHLVVHARTKVEGYRPPASWEWLA 185

Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
              +A    PVY N    S    +  R+I+  V+ VM+G G + +P +  +I
Sbjct: 186 RVREAVA-VPVYANRK--SGRRRIGCREIS-GVEDVMLGCGLVSRPDLARQI 233


>UniRef50_A1AW94 Cluster: TIM-barrel protein, yjbN family; n=1;
           Candidatus Ruthia magnifica str. Cm (Calyptogena
           magnifica)|Rep: TIM-barrel protein, yjbN family - Ruthia
           magnifica subsp. Calyptogena magnifica
          Length = 322

 Score = 45.2 bits (102), Expect = 0.005
 Identities = 44/211 (20%), Positives = 87/211 (41%), Gaps = 16/211 (7%)

Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334
           EM    ++L G K    L+  +  E     Q+ G+ P  + + A++ Q+    + I++N+
Sbjct: 36  EMVTARAILYGNKNR--LLDFNVCEHPLVLQLGGSEPKEMAQAAKIAQD-WGYNEININV 92

Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTI--VP 392
           GCP + +     G  +M     +   V    +++ +P TVK R GV         +  V 
Sbjct: 93  GCPSNRVQSSNFGVCLMQTPQVVAQCVDAMRQMVDVPITVKSRIGVDNMDSYDELVNFVA 152

Query: 393 KMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444
            + + G   + +H R         +E R     ++E +    +      +  NG I   E
Sbjct: 153 TVESSGCDNLVIHARKAWLKGLSPKENRSVPKLNYERVYQIKRDFPHLAIGINGGIMDME 212

Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475
             ++  +    V  VM+GR    +P++  ++
Sbjct: 213 SSLQHLE---HVDSVMLGRAVYHQPYLLRKV 240


>UniRef50_Q59YG4 Cluster: Potential tRNA dihydrouridine synthase;
           n=2; Saccharomycetales|Rep: Potential tRNA
           dihydrouridine synthase - Candida albicans (Yeast)
          Length = 433

 Score = 45.2 bits (102), Expect = 0.005
 Identities = 59/284 (20%), Positives = 120/284 (42%), Gaps = 33/284 (11%)

Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKG---LKQEWA----LV 293
           I++ NKL L+P+   G LP R +   +G D+      + + +L+    + QE      +V
Sbjct: 2   IEYANKLCLAPMVRSGELPIRLLSLRYGCDLLWTPELVDKKILQSTRIINQELNTIDYIV 61

Query: 294 KRHETED----LFGA----------QICGNNPYIITKVAQLLQENTELDFIDLNIGCPID 339
             H+  D    +F            Q+  ++P +    A+ + +  ++D IDLN GCP +
Sbjct: 62  SNHQQSDKKTVIFRKHPVETGRLILQLGSSDPQLAVDAARKVID--DVDGIDLNCGCPKN 119

Query: 340 LIYKKGGGSGMMHRLPALETSVRCASKLLSIP--FTVKMRTGVYQDKKITHTIVPKMSNW 397
                G G+ ++     L + +    + + IP   ++  +  ++ +   +  ++ K+   
Sbjct: 120 FSTHSGMGAELLKTPDKLCSILINLVEKIGIPNKKSISCKIRLFNNYDQSKNLIEKILQT 179

Query: 398 GASLITVHGRSREARYTKSSDWEYIETCAQAATPCPV--YGNGDIFSYEDYVEMRKIAPT 455
           G S +T+H R+   R  +   W ++           V    NG++ +  D   ++     
Sbjct: 180 GISNLTIHCRTPIMRNRQDPVWNFLPKLIPIIQTAGVNLVINGNMQNVADLKNLQSALND 239

Query: 456 VKG----VMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKY 495
             G    +MI   A   P +F+   + +   I  ++ FEI +KY
Sbjct: 240 NGGGKLSIMIAEAAEANPSVFSHSPKPQCLII--QELFEICQKY 281


>UniRef50_A2QES0 Cluster: Contig An02c0390, complete genome; n=12;
           Pezizomycotina|Rep: Contig An02c0390, complete genome -
           Aspergillus niger
          Length = 446

 Score = 45.2 bits (102), Expect = 0.005
 Identities = 43/175 (24%), Positives = 77/175 (44%), Gaps = 13/175 (7%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364
           QI    P I  + A+L+    ++  ID+N GCP       G G+ ++     L   +   
Sbjct: 108 QIGTATPEIAVQAAKLVAG--DVAGIDVNSGCPKPFSTSGGMGAALLKTPDKLVAILEAL 165

Query: 365 SKLLSIPFT--VKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422
            K +  PF   + ++  + +D + T  +V ++   G + +TVH R+   R  + +  + +
Sbjct: 166 VKEVGTPFQIGISVKIRILKDPEETRALVSRLVKTGITGLTVHCRTPPMRPRERAIRDQV 225

Query: 423 ----ETCAQAATPCPVYGNGDIFSY-EDYVEMRKIAPTVKGVMIGRGALIKPWIF 472
               + C +A   C +  NGD+ S  E +  M++    V G MI   A   P  F
Sbjct: 226 RMIADICHEAGVACVI--NGDVTSKDEGHALMKEFG--VDGAMIATAAEANPSCF 276


>UniRef50_O51679 Cluster: Histidine phosphokinase/phophatase,
           putative; n=3; Borrelia burgdorferi group|Rep: Histidine
           phosphokinase/phophatase, putative - Borrelia
           burgdorferi (Lyme disease spirochete)
          Length = 335

 Score = 44.8 bits (101), Expect = 0.007
 Identities = 65/276 (23%), Positives = 117/276 (42%), Gaps = 27/276 (9%)

Query: 247 LYLSPLTTVGNLPFRRICKEFGA-----DVTCGEMALCESLLKGLKQ--EWALVKRHETE 299
           + L+P+  V +  FR +    G+      +   E    + +L G KQ  +   +K +E  
Sbjct: 18  MILAPMEDVTDTVFRNLIHLIGSAEGEPHIYFTEFISTKGILNGSKQSVQHVFLKPNELN 77

Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359
               AQI GN P    +  ++L  +     ID+N+GCP   I KKG  S +++   +L  
Sbjct: 78  RPLIAQIWGNVPEQFYRAIEILG-SMGFWGIDINMGCPKSKIIKKGVCSALINN-KSLAK 135

Query: 360 SVRCASK----LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGR--SREARY 413
            +  ASK      ++P +VK R G    +      +  +      ++TV+ R    +++ 
Sbjct: 136 EIILASKEACARFNLPLSVKTRHGFSYPE--VDDWLGFLLGLEIDMLTVYPRLAVNQSKG 193

Query: 414 TKSSD--WEYIETCAQAATPCPVYGNGDIFSYED---YVEMRKIAPTVKGVMIGRGALIK 468
             + D  +E ++     +    + GNGD+ S ++   YV+       + G+M GRG    
Sbjct: 194 PVNFDIFYELVKLRNNLSPSTLIIGNGDVLSLKEARYYVDKY----LIDGIMFGRGIFDN 249

Query: 469 PWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWG 504
             +F    +  + D +   R  ILK +       WG
Sbjct: 250 LNLFKPFSKHFL-DSNLNFRLNILKFHIKDFHATWG 284


>UniRef50_UPI000150A3F7 Cluster: hypothetical protein TTHERM_00141090;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00141090 - Tetrahymena thermophila SB210
          Length = 1642

 Score = 44.0 bits (99), Expect = 0.011
 Identities = 48/199 (24%), Positives = 90/199 (45%), Gaps = 15/199 (7%)

Query: 17   LQKSNII---EEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKNDSKTKKRGQN-K 72
            +QKSNI    EE S   E +K     A  D+  ++  + +++I     ++K +K   N K
Sbjct: 1230 IQKSNIFAIKEEVSVTQETQKTQPQKALVDNYIIDISQ-QVQINAQNQNNKEEKMNINDK 1288

Query: 73   SRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFL-NSKPKDIGDQCHVY 131
               K      +SK     L+ E  +Q K   +N  + I +  Q   N+  +D   Q  +Y
Sbjct: 1289 LISKNESKENQSKSVDISLNNERKQQEK---HNISQIIIEKSQVTSNNINQDYIKQNQLY 1345

Query: 132  KVRGKCPRGIA-CRYGSDHITADGFNIVNREKFDQWKDDTKNTLQPSLQTQLQKKKYNFD 190
            +++ +   GI     G + +    F    + K  Q K D  +  Q S+ +Q+Q  ++N  
Sbjct: 1346 EIKEESSVGIQNLNIGMNDVNKKDFQ---KNKIQQIKQDV-SVSQDSV-SQVQSIQFNIQ 1400

Query: 191  LAEKLVKHLDTRNKSVDKN 209
            + ++++  L+ + K + KN
Sbjct: 1401 VQQEVISQLEIQKKDIQKN 1419


>UniRef50_Q4PIC3 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 364

 Score = 44.0 bits (99), Expect = 0.011
 Identities = 47/185 (25%), Positives = 82/185 (44%), Gaps = 22/185 (11%)

Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM--HRLPALETSVR 362
           Q+ GNN   + + A+ +      D IDLN+GCP     +   G+ ++     P +   V 
Sbjct: 91  QLAGNNVQQLVEAARRVAPYA--DAIDLNLGCPQRHAEQGHYGACLLPKQNWPLVAEIVS 148

Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGR-SREARYTKS-SDWE 420
              + + +P T K+R  V   K+ T  +   +++ G+SL+TVH R +  AR  K  +D +
Sbjct: 149 GMVQAVDVPITTKIRLPV--PKEQTAQLAVMLAHAGSSLVTVHPRFASSARRRKGLADLD 206

Query: 421 YI-------------ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALI 467
            +              +  Q      V  NG++  ++D V   ++     GVM+G   L 
Sbjct: 207 QVVKVREALQAQGLLRSAEQPHKDTAVVSNGNVQCWQDVVNNLELT-GASGVMVGETLLQ 265

Query: 468 KPWIF 472
            P +F
Sbjct: 266 NPALF 270


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.317    0.135    0.409 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 697,681,116
Number of Sequences: 1657284
Number of extensions: 31093427
Number of successful extensions: 101948
Number of sequences better than 10.0: 441
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 251
Number of HSP's that attempted gapping in prelim test: 100590
Number of HSP's gapped (non-prelim): 1032
length of query: 591
length of database: 575,637,011
effective HSP length: 105
effective length of query: 486
effective length of database: 401,622,191
effective search space: 195188384826
effective search space used: 195188384826
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 75 (34.3 bits)

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