BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001335-TA|BGIBMGA001335-PA|IPR001269|Dihydrouridine synthase, DuS (591 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q17M24 Cluster: tRNA-dihydrouridine synthase; n=1; Aede... 643 0.0 UniRef50_Q7PVV7 Cluster: ENSANGP00000016833; n=2; Endopterygota|... 641 0.0 UniRef50_A7S213 Cluster: Predicted protein; n=1; Nematostella ve... 620 e-176 UniRef50_Q9VIS4 Cluster: CG10463-PA; n=3; Sophophora|Rep: CG1046... 606 e-172 UniRef50_Q96G46 Cluster: tRNA-dihydrouridine synthase 3-like; n=... 586 e-166 UniRef50_Q91XI1 Cluster: tRNA-dihydrouridine synthase 3-like; n=... 583 e-165 UniRef50_UPI000058804E Cluster: PREDICTED: similar to MGC53781 p... 549 e-155 UniRef50_Q6PEH0 Cluster: Zgc:63779; n=8; Chordata|Rep: Zgc:63779... 541 e-152 UniRef50_A4RQU5 Cluster: Predicted protein; n=2; Ostreococcus|Re... 489 e-137 UniRef50_UPI00015B6197 Cluster: PREDICTED: similar to CG10463-PA... 483 e-135 UniRef50_Q9TYN2 Cluster: Putative uncharacterized protein Y37E11... 455 e-126 UniRef50_Q01ML2 Cluster: H0613H07.1 protein; n=10; Eukaryota|Rep... 451 e-125 UniRef50_Q582L4 Cluster: TRNA-dihydrouridine synthase 3, putativ... 418 e-115 UniRef50_Q54CU9 Cluster: Putative uncharacterized protein; n=1; ... 415 e-114 UniRef50_Q010A0 Cluster: tRNA-dihydrouridine synthase; n=1; Ostr... 410 e-113 UniRef50_Q5KC68 Cluster: TRNA dihydrouridine synthase, putative;... 407 e-112 UniRef50_Q4QEF9 Cluster: Putative uncharacterized protein; n=3; ... 404 e-111 UniRef50_A3LUK5 Cluster: Dihydrouridine synthase of tRNA; n=6; S... 399 e-109 UniRef50_Q6C4K3 Cluster: Similar to DEHA0D12364g Debaryomyces ha... 392 e-107 UniRef50_A4S3Q5 Cluster: Predicted protein; n=2; Eukaryota|Rep: ... 386 e-105 UniRef50_Q5CRK5 Cluster: Ylr401cp-like protein with 2 CCCH domai... 342 2e-92 UniRef50_UPI0000499494 Cluster: conserved hypothetical protein; ... 332 2e-89 UniRef50_Q9UTH9 Cluster: tRNA dihydrouridine synthase Dus3; n=1;... 324 4e-87 UniRef50_Q2UL89 Cluster: Uncharacterized conserved protein; n=15... 308 4e-82 UniRef50_Q06053 Cluster: tRNA-dihydrouridine synthase 3; n=6; Sa... 245 2e-63 UniRef50_Q2HDP2 Cluster: Putative uncharacterized protein; n=1; ... 244 7e-63 UniRef50_Q7X346 Cluster: Putative uncharacterized protein; n=1; ... 200 8e-50 UniRef50_A4S604 Cluster: Predicted protein; n=1; Ostreococcus lu... 197 8e-49 UniRef50_Q7R3K2 Cluster: GLP_158_4738_3071; n=1; Giardia lamblia... 183 1e-44 UniRef50_A4XH30 Cluster: Putative TIM-barrel protein, nifR3 fami... 157 8e-37 UniRef50_Q899H0 Cluster: Nitrogen regulation protein nifR3; n=24... 144 8e-33 UniRef50_A5BP75 Cluster: Putative uncharacterized protein; n=1; ... 140 1e-31 UniRef50_A6LGT0 Cluster: Putative TIM-barrel enzyme; n=1; Paraba... 138 5e-31 UniRef50_Q7MXX6 Cluster: TIM-barrel protein, putative, NifR3 fam... 136 1e-30 UniRef50_Q1IVR5 Cluster: Dihydrouridine synthase TIM-barrel prot... 135 3e-30 UniRef50_Q0F181 Cluster: Dihydrouridine synthase TIM-barrel prot... 135 3e-30 UniRef50_Q64MI4 Cluster: Putative TIM-barrel enzyme; n=3; Bacter... 133 1e-29 UniRef50_Q9RDC6 Cluster: Putative uncharacterized protein SCO249... 132 3e-29 UniRef50_Q8GQD1 Cluster: NifR; n=5; Leptospira|Rep: NifR - Lepto... 132 3e-29 UniRef50_Q6F288 Cluster: TRNA dihydrouridine synthetase; n=3; Mo... 132 3e-29 UniRef50_A1IF01 Cluster: Dihydrouridine synthase family protein;... 130 1e-28 UniRef50_Q6AJZ5 Cluster: TRNA-dihydrouridine synthase; n=1; Desu... 129 2e-28 UniRef50_Q1Q3Q8 Cluster: Strongly similar to tRNA-dihydrouridine... 129 2e-28 UniRef50_Q8KB61 Cluster: TIM-barrel protein, nifR3 family; n=10;... 128 3e-28 UniRef50_Q6MRF1 Cluster: Transcription regulator homolog yacF; n... 128 3e-28 UniRef50_Q0YFW9 Cluster: Dihydrouridine synthase TIM-barrel prot... 128 3e-28 UniRef50_Q1NXZ7 Cluster: Dihydrouridine synthase TIM-barrel prot... 128 4e-28 UniRef50_Q2RZL4 Cluster: NifR3 family enzyme; n=1; Salinibacter ... 128 5e-28 UniRef50_Q2IG49 Cluster: Dihydrouridine synthase TIM-barrel prot... 128 5e-28 UniRef50_A6CBK4 Cluster: Predicted TIM-barrel enzyme, possibly d... 127 9e-28 UniRef50_Q9Z7D8 Cluster: Predicted oxidoreductase; n=7; Chlamydi... 126 2e-27 UniRef50_Q5M689 Cluster: Possible transcriptional regulator; n=2... 126 2e-27 UniRef50_Q74EF7 Cluster: Dihydrouridine synthase family protein;... 125 3e-27 UniRef50_A2FJB5 Cluster: TIM-barrel protein, nifR3 family protei... 125 3e-27 UniRef50_A5D5Q0 Cluster: TRNA-dihydrouridine synthase; n=5; Firm... 125 4e-27 UniRef50_O25427 Cluster: Probable tRNA-dihydrouridine synthase; ... 124 9e-27 UniRef50_Q1VN28 Cluster: Dihydrouridine synthase TIM-barrel prot... 123 2e-26 UniRef50_Q9ZED2 Cluster: Probable tRNA-dihydrouridine synthase; ... 123 2e-26 UniRef50_A6EDJ3 Cluster: Probable TIM-barrel protein, NifR3 fami... 122 3e-26 UniRef50_P37567 Cluster: Probable tRNA-dihydrouridine synthase 1... 122 4e-26 UniRef50_A4TZK1 Cluster: Dihydrouridine synthase, DuS; n=4; Prot... 121 6e-26 UniRef50_A4EC62 Cluster: Putative uncharacterized protein; n=1; ... 120 1e-25 UniRef50_O67533 Cluster: Probable tRNA-dihydrouridine synthase; ... 120 1e-25 UniRef50_Q8G7W8 Cluster: Possible NifR3-like protein; n=4; Bifid... 119 2e-25 UniRef50_A5EVV4 Cluster: Dihydrouridine synthase; n=1; Dicheloba... 117 8e-25 UniRef50_Q6A959 Cluster: TIM-barrel enzyme, NifR3 family; n=1; P... 116 2e-24 UniRef50_A4M5I1 Cluster: Dihydrouridine synthase, DuS; n=1; Petr... 115 3e-24 UniRef50_A6PPM6 Cluster: Dihydrouridine synthase, DuS; n=1; Vict... 115 4e-24 UniRef50_Q9CLW3 Cluster: tRNA-dihydrouridine synthase B; n=17; P... 115 4e-24 UniRef50_A0LJ96 Cluster: Putative TIM-barrel protein, nifR3 fami... 113 9e-24 UniRef50_Q2RM54 Cluster: Dihydrouridine synthase TIM-barrel prot... 113 1e-23 UniRef50_A6NW05 Cluster: Putative uncharacterized protein; n=1; ... 113 1e-23 UniRef50_Q3E0H8 Cluster: Dihydrouridine synthase TIM-barrel prot... 113 2e-23 UniRef50_Q0B0N8 Cluster: Putative TIM-barrel protein, NifR3 fami... 113 2e-23 UniRef50_Q489F6 Cluster: NifR3/Smm1 family protein; n=2; Proteob... 112 2e-23 UniRef50_A6BZR9 Cluster: Predicted TIM-barrel enzyme, possibly d... 112 2e-23 UniRef50_A6DCX2 Cluster: tRNA-dihydrouridine synthase B; n=1; Ca... 112 3e-23 UniRef50_Q8PX79 Cluster: NifR3-like protein; n=5; Archaea|Rep: N... 111 4e-23 UniRef50_Q6M9N8 Cluster: Putative uncharacterized protein; n=1; ... 111 5e-23 UniRef50_Q6SFW7 Cluster: NifR3/Smm1 family protein; n=1; uncultu... 111 5e-23 UniRef50_Q6MAU6 Cluster: Putative uncharacterized protein yohI; ... 109 3e-22 UniRef50_Q251N6 Cluster: Putative uncharacterized protein; n=2; ... 107 6e-22 UniRef50_Q31II6 Cluster: Dihydrouridine synthase; n=1; Thiomicro... 107 8e-22 UniRef50_A4YUQ6 Cluster: Putative tRNA-dihydrouridine synthase; ... 107 8e-22 UniRef50_Q0G7A4 Cluster: Nitrogen regulation protein nifr3; n=2;... 107 1e-21 UniRef50_A7HK00 Cluster: Dihydrouridine synthase DuS; n=4; Therm... 107 1e-21 UniRef50_O53835 Cluster: Probable tRNA-dihydrouridine synthase; ... 107 1e-21 UniRef50_Q0FAI7 Cluster: tRNA-dihydrouridine synthase, putative;... 106 1e-21 UniRef50_Q8YAB9 Cluster: Lmo0227 protein; n=55; Bacteria|Rep: Lm... 106 2e-21 UniRef50_Q14SX5 Cluster: Putative dihydrouridine synthase; n=1; ... 106 2e-21 UniRef50_Q9RRP8 Cluster: NifR3 protein; n=2; Deinococcus|Rep: Ni... 105 3e-21 UniRef50_Q3AZ67 Cluster: Dihydrouridine synthase TIM-barrel prot... 105 3e-21 UniRef50_Q5FTP7 Cluster: Nitrogen assimilation regulatory protei... 104 6e-21 UniRef50_Q2RTR9 Cluster: Dihydrouridine synthase TIM-barrel prot... 104 6e-21 UniRef50_Q55724 Cluster: Probable tRNA-dihydrouridine synthase 1... 104 6e-21 UniRef50_O83945 Cluster: Probable tRNA-dihydrouridine synthase; ... 104 8e-21 UniRef50_Q00XL7 Cluster: TRNA-dihydrouridine synthase; n=1; Ostr... 103 1e-20 UniRef50_Q090Q9 Cluster: TRNA-dihydrouridine synthase B; n=2; Cy... 102 2e-20 UniRef50_A7BE39 Cluster: Putative uncharacterized protein; n=1; ... 102 2e-20 UniRef50_Q607L4 Cluster: TIM-barrel protein, yjbN family; n=10; ... 102 3e-20 UniRef50_A7CWF1 Cluster: Putative TIM-barrel protein, nifR3 fami... 101 7e-20 UniRef50_Q5ZRM0 Cluster: Nitrogen regulation protein; n=4; Legio... 100 1e-19 UniRef50_A6DPY9 Cluster: Putative uncharacterized protein; n=1; ... 99 2e-19 UniRef50_Q8RFK3 Cluster: Nitrogen regulation protein NIFR3; n=3;... 99 3e-19 UniRef50_Q0C0N1 Cluster: Putative tRNA-dihydrouridine synthase; ... 99 3e-19 UniRef50_Q5CSA9 Cluster: Dus1p, tRNA dihydrouridine synthase; n=... 99 4e-19 UniRef50_Q08111 Cluster: Probable tRNA-dihydrouridine synthase; ... 98 5e-19 UniRef50_Q89LQ7 Cluster: Nitrogen regulation protein; n=22; Alph... 98 7e-19 UniRef50_Q9A7I4 Cluster: Nitrogen regulation protein Nifr3; n=2;... 97 9e-19 UniRef50_A7DPL5 Cluster: Putative TIM-barrel protein, nifR3 fami... 97 9e-19 UniRef50_A0EG06 Cluster: Chromosome undetermined scaffold_94, wh... 96 3e-18 UniRef50_Q8ZAX7 Cluster: tRNA-dihydrouridine synthase B; n=214; ... 95 6e-18 UniRef50_Q54ES7 Cluster: Putative uncharacterized protein; n=1; ... 92 3e-17 UniRef50_Q1QZQ6 Cluster: Dihydrouridine synthase, DuS; n=1; Chro... 92 4e-17 UniRef50_Q8SUV4 Cluster: Putative uncharacterized protein ECU07_... 92 4e-17 UniRef50_A4RVX6 Cluster: Predicted protein; n=2; Ostreococcus|Re... 91 8e-17 UniRef50_A3VNG3 Cluster: Dihydrouridine synthase TIM-barrel prot... 91 1e-16 UniRef50_A4S141 Cluster: Predicted protein; n=1; Ostreococcus lu... 91 1e-16 UniRef50_A5K1E0 Cluster: tRNA-dihydrouridine synthase, putative;... 89 2e-16 UniRef50_Q9JUP6 Cluster: tRNA-dihydrouridine synthase C; n=4; Ne... 89 3e-16 UniRef50_O52532 Cluster: tRNA-dihydrouridine synthase B; n=6; Ga... 89 3e-16 UniRef50_O74553 Cluster: tRNA dihydrouridine synthase Dus4; n=1;... 89 4e-16 UniRef50_Q6P1R4 Cluster: tRNA-dihydrouridine synthase 1-like; n=... 88 7e-16 UniRef50_Q7UXK8 Cluster: Putative uncharacterized protein; n=3; ... 87 2e-15 UniRef50_Q7UKE8 Cluster: Putative uncharacterized protein; n=2; ... 87 2e-15 UniRef50_Q30WR3 Cluster: Dihydrouridine synthase family protein;... 87 2e-15 UniRef50_Q9FH91 Cluster: Gb|AAF51525.1; n=6; Magnoliophyta|Rep: ... 87 2e-15 UniRef50_Q9VPM1 Cluster: CG3645-PA, isoform A; n=2; Diptera|Rep:... 86 2e-15 UniRef50_Q9HGN6 Cluster: tRNA dihydrouridine synthase Dus1; n=1;... 86 2e-15 UniRef50_A6DU09 Cluster: Dihydrouridine synthase family protein;... 86 3e-15 UniRef50_Q00RI1 Cluster: OSIGBa0125M19.5 protein; n=9; Magnoliop... 85 7e-15 UniRef50_Q5LRN6 Cluster: TRNA-dihydrouridine synthase, putative;... 84 9e-15 UniRef50_Q54XQ6 Cluster: Putative uncharacterized protein; n=1; ... 84 9e-15 UniRef50_Q8YMN5 Cluster: Transcriptional regulator; n=5; Bacteri... 84 1e-14 UniRef50_A3RPJ2 Cluster: TRNA-dihydrouridine synthase; n=2; Prot... 83 2e-14 UniRef50_Q4PG83 Cluster: Putative uncharacterized protein; n=1; ... 83 2e-14 UniRef50_Q4AHG7 Cluster: Dihydrouridine synthase, DuS; n=1; Chlo... 82 4e-14 UniRef50_UPI0000D5693C Cluster: PREDICTED: similar to dihydrouri... 82 5e-14 UniRef50_Q47C15 Cluster: Dihydrouridine synthase, DuS; n=2; Beta... 82 5e-14 UniRef50_Q5A4Y0 Cluster: Potential tRNA dihydrouridine synthase;... 81 6e-14 UniRef50_A6W1E8 Cluster: Dihydrouridine synthase DuS; n=1; Marin... 81 8e-14 UniRef50_A1VHK2 Cluster: Dihydrouridine synthase, DuS; n=4; Desu... 81 8e-14 UniRef50_Q5KP54 Cluster: TRNA dihydrouridine synthase, putative;... 81 1e-13 UniRef50_Q8XYX1 Cluster: tRNA-dihydrouridine synthase C; n=26; P... 81 1e-13 UniRef50_A1SX05 Cluster: Dihydrouridine synthase, DuS; n=3; Alte... 80 1e-13 UniRef50_O95620 Cluster: tRNA-dihydrouridine synthase 4-like; n=... 80 1e-13 UniRef50_Q9VY45 Cluster: CG1434-PA; n=6; Endopterygota|Rep: CG14... 80 2e-13 UniRef50_Q8A2H9 Cluster: Putative nifR3 family TIM-barrel enzyme... 79 2e-13 UniRef50_A7AQM0 Cluster: Dihydrouridine synthase, putative; n=1;... 79 2e-13 UniRef50_A3JG66 Cluster: Putative uncharacterized protein; n=3; ... 79 4e-13 UniRef50_Q9XVN8 Cluster: Putative uncharacterized protein; n=2; ... 79 4e-13 UniRef50_P53759 Cluster: tRNA-dihydrouridine synthase 1; n=11; S... 79 4e-13 UniRef50_A6GHV6 Cluster: Dihydrouridine synthase family protein;... 78 6e-13 UniRef50_Q884C6 Cluster: tRNA-dihydrouridine synthase C; n=8; Pr... 78 6e-13 UniRef50_Q7RX85 Cluster: Putative uncharacterized protein NCU000... 77 1e-12 UniRef50_Q06063 Cluster: tRNA-dihydrouridine synthase 4; n=10; S... 77 1e-12 UniRef50_Q6MNE9 Cluster: Nitrogen regulation protein nifR3; n=1;... 77 1e-12 UniRef50_A4E892 Cluster: Putative uncharacterized protein; n=1; ... 76 2e-12 UniRef50_Q6AKJ6 Cluster: Putative uncharacterized protein; n=1; ... 76 3e-12 UniRef50_Q9XWJ9 Cluster: Putative uncharacterized protein; n=2; ... 76 3e-12 UniRef50_Q1JWD3 Cluster: Dihydrouridine synthase, DuS; n=1; Desu... 75 4e-12 UniRef50_A6PMB8 Cluster: Dihydrouridine synthase, DuS; n=1; Vict... 75 4e-12 UniRef50_Q127F8 Cluster: Dihydrouridine synthase, DuS; n=3; Prot... 75 5e-12 UniRef50_UPI00015B403F Cluster: PREDICTED: similar to MGC79829 p... 75 7e-12 UniRef50_A7T8A1 Cluster: Predicted protein; n=1; Nematostella ve... 75 7e-12 UniRef50_Q5HJT5 Cluster: Probable tRNA-dihydrouridine synthase; ... 75 7e-12 UniRef50_Q9VJ06 Cluster: CG10495-PA; n=2; Sophophora|Rep: CG1049... 74 1e-11 UniRef50_Q6AJ40 Cluster: Putative uncharacterized protein; n=1; ... 73 2e-11 UniRef50_Q9NX74 Cluster: tRNA-dihydrouridine synthase 2-like; n=... 73 2e-11 UniRef50_A7AAN4 Cluster: Putative uncharacterized protein; n=2; ... 72 4e-11 UniRef50_Q73RG6 Cluster: Dihydrouridine synthase, putative; n=1;... 72 5e-11 UniRef50_Q4D174 Cluster: Dihydrouridine synthase (Dus), putative... 72 5e-11 UniRef50_A6VYA3 Cluster: TIM-barrel protein, yjbN family; n=8; P... 71 9e-11 UniRef50_Q5KPM6 Cluster: Putative uncharacterized protein; n=2; ... 71 9e-11 UniRef50_Q4WRF0 Cluster: Dihydrouridine synthase family protein,... 71 1e-10 UniRef50_UPI0000499E32 Cluster: conserved hypothetical protein; ... 70 2e-10 UniRef50_Q1N033 Cluster: Putative uncharacterized protein; n=1; ... 70 2e-10 UniRef50_Q0IFC6 Cluster: tRNA-dihydrouridine synthase; n=2; Culi... 70 2e-10 UniRef50_A6P2M8 Cluster: Putative uncharacterized protein; n=1; ... 70 2e-10 UniRef50_A4AAB0 Cluster: TRNA-dihydrouridine synthase C; n=2; un... 69 3e-10 UniRef50_O74731 Cluster: tRNA dihydrouridine synthase Dus2; n=1;... 69 4e-10 UniRef50_Q54QJ2 Cluster: Putative uncharacterized protein; n=1; ... 69 5e-10 UniRef50_Q4S086 Cluster: Chromosome undetermined SCAF14784, whol... 68 6e-10 UniRef50_Q21L63 Cluster: Dihydrouridine synthase, DuS; n=1; Sacc... 68 6e-10 UniRef50_A4BWB1 Cluster: Putative uncharacterized protein; n=5; ... 68 6e-10 UniRef50_Q7VKU5 Cluster: tRNA-dihydrouridine synthase C; n=118; ... 68 6e-10 UniRef50_UPI00015B40A4 Cluster: PREDICTED: similar to tRNA-dihyd... 68 8e-10 UniRef50_A2DYY3 Cluster: Putative uncharacterized protein; n=1; ... 68 8e-10 UniRef50_Q57V78 Cluster: TRNA-dihydrouridine synthase 1, putativ... 67 1e-09 UniRef50_O31546 Cluster: Probable tRNA-dihydrouridine synthase 2... 67 1e-09 UniRef50_UPI000023EA9A Cluster: hypothetical protein FG07217.1; ... 67 1e-09 UniRef50_Q6MNE4 Cluster: Dihydrouridine synthase family protein;... 67 1e-09 UniRef50_Q583Y8 Cluster: TRNA-dihydrouridine synthase 4, putativ... 67 1e-09 UniRef50_A2F0D1 Cluster: Putative uncharacterized protein; n=1; ... 66 3e-09 UniRef50_A1AT39 Cluster: Dihydrouridine synthase, DuS; n=7; Desu... 65 4e-09 UniRef50_Q09504 Cluster: Uncharacterized tRNA-dihydrouridine syn... 65 6e-09 UniRef50_A4BCJ5 Cluster: NifR3/Smm1 family protein; n=2; Gammapr... 64 8e-09 UniRef50_A2FU21 Cluster: Putative uncharacterized protein; n=1; ... 64 1e-08 UniRef50_Q22A31 Cluster: TIM-barrel protein, yjbN family; n=1; T... 63 2e-08 UniRef50_Q550J6 Cluster: Putative uncharacterized protein; n=2; ... 63 2e-08 UniRef50_Q5KGP0 Cluster: Putative uncharacterized protein; n=3; ... 62 3e-08 UniRef50_A7EMF2 Cluster: Putative uncharacterized protein; n=1; ... 62 4e-08 UniRef50_A2ACC0 Cluster: Novel protein; n=17; Eumetazoa|Rep: Nov... 61 7e-08 UniRef50_Q4UGK9 Cluster: Putative uncharacterized protein; n=2; ... 61 7e-08 UniRef50_Q4PAE4 Cluster: Putative uncharacterized protein; n=1; ... 61 7e-08 UniRef50_Q5SMC7 Cluster: TRNA-dihydrouridine synthase; n=2; Ther... 60 2e-07 UniRef50_Q83D40 Cluster: TIM-barrel protein, yjbN family; n=7; B... 60 2e-07 UniRef50_Q4FQ57 Cluster: Possible tRNA-dihydrouridine synthase; ... 59 3e-07 UniRef50_A4RU69 Cluster: Predicted protein; n=2; Ostreococcus|Re... 58 5e-07 UniRef50_Q3IKP0 Cluster: TRNA-dihydrouridine synthase C; n=5; Al... 58 9e-07 UniRef50_A5Z3X7 Cluster: Putative uncharacterized protein; n=1; ... 57 1e-06 UniRef50_Q4PBU9 Cluster: Putative uncharacterized protein; n=1; ... 56 2e-06 UniRef50_Q97DM0 Cluster: Predicted TIM-barrel enzyme, nifR3 fami... 56 3e-06 UniRef50_Q7R1J1 Cluster: GLP_38_15456_16676; n=1; Giardia lambli... 56 3e-06 UniRef50_A1IED4 Cluster: Putative uncharacterized protein; n=1; ... 56 4e-06 UniRef50_A0EAZ6 Cluster: Chromosome undetermined scaffold_87, wh... 56 4e-06 UniRef50_UPI0000DAE45A Cluster: hypothetical protein Rgryl_01000... 55 5e-06 UniRef50_Q4FLD8 Cluster: Putative uncharacterized protein; n=2; ... 55 5e-06 UniRef50_A2DHB4 Cluster: Putative uncharacterized protein; n=1; ... 55 5e-06 UniRef50_Q7R9R0 Cluster: Uncharacterized protein family UPF0034,... 54 8e-06 UniRef50_A5WG83 Cluster: TIM-barrel protein, yjbN family; n=4; M... 54 1e-05 UniRef50_Q04VP3 Cluster: TRNA-dihydrouridine synthase; n=4; Lept... 53 2e-05 UniRef50_Q4Q391 Cluster: Putative uncharacterized protein; n=3; ... 53 2e-05 UniRef50_Q9PGB5 Cluster: tRNA-dihydrouridine synthase A; n=8; Pr... 53 2e-05 UniRef50_A2EN54 Cluster: Putative uncharacterized protein; n=1; ... 53 2e-05 UniRef50_Q5ZVH8 Cluster: Zinc binding TIM barrel protein, YjbN f... 52 4e-05 UniRef50_A6GGZ7 Cluster: Putative uncharacterized protein; n=2; ... 52 4e-05 UniRef50_A1RNI1 Cluster: TIM-barrel protein, yjbN family; n=30; ... 52 6e-05 UniRef50_Q6BX60 Cluster: Debaryomyces hansenii chromosome B of s... 52 6e-05 UniRef50_A6RW05 Cluster: Putative uncharacterized protein; n=1; ... 52 6e-05 UniRef50_O51243 Cluster: Putative uncharacterized protein BB0225... 51 8e-05 UniRef50_Q0VPD7 Cluster: TIM-barrel protein, yjbN family; n=4; B... 51 8e-05 UniRef50_A7DKP5 Cluster: Dihydrouridine synthase, DuS; n=2; Meth... 51 1e-04 UniRef50_Q6C002 Cluster: Yarrowia lipolytica chromosome F of str... 51 1e-04 UniRef50_A2EF32 Cluster: Dihydrouridine synthase, putative; n=1;... 50 1e-04 UniRef50_A6RVN2 Cluster: Putative uncharacterized protein; n=2; ... 50 1e-04 UniRef50_A6U9Y2 Cluster: Dihydrouridine synthase DuS; n=2; Sinor... 50 2e-04 UniRef50_Q7R3H4 Cluster: GLP_158_49916_51304; n=1; Giardia lambl... 50 2e-04 UniRef50_A5GPV9 Cluster: TRNA-dihydrouridine synthase A; n=21; C... 49 3e-04 UniRef50_Q7UBC5 Cluster: tRNA-dihydrouridine synthase A; n=231; ... 49 3e-04 UniRef50_A7AWB5 Cluster: Dihydrouridine synthase (Dus) domain co... 47 0.001 UniRef50_A4SY29 Cluster: Dihydrouridine synthase, DuS; n=1; Poly... 46 0.002 UniRef50_A3AVU4 Cluster: Putative uncharacterized protein; n=1; ... 46 0.003 UniRef50_P96192 Cluster: tRNA-dihydrouridine synthase C; n=1; Az... 46 0.004 UniRef50_A1AW94 Cluster: TIM-barrel protein, yjbN family; n=1; C... 45 0.005 UniRef50_Q59YG4 Cluster: Potential tRNA dihydrouridine synthase;... 45 0.005 UniRef50_A2QES0 Cluster: Contig An02c0390, complete genome; n=12... 45 0.005 UniRef50_O51679 Cluster: Histidine phosphokinase/phophatase, put... 45 0.007 UniRef50_UPI000150A3F7 Cluster: hypothetical protein TTHERM_0014... 44 0.011 UniRef50_Q4PIC3 Cluster: Putative uncharacterized protein; n=1; ... 44 0.011 UniRef50_O32363 Cluster: NifR3-like protein; n=17; Campylobacter... 43 0.020 UniRef50_A5EXU5 Cluster: TRNA-dihydrouridine synthase A; n=1; Di... 43 0.020 UniRef50_UPI000023CFE7 Cluster: hypothetical protein FG01258.1; ... 43 0.026 UniRef50_Q8I3B2 Cluster: Putative uncharacterized protein PFI017... 42 0.046 UniRef50_Q2H6D9 Cluster: Putative uncharacterized protein; n=1; ... 42 0.046 UniRef50_Q5LQV9 Cluster: TRNA-dihydrouridine synthase A; n=46; B... 42 0.061 UniRef50_Q7R8B0 Cluster: Transcription factor iiib 70 kDa subuni... 42 0.061 UniRef50_Q4YRY8 Cluster: Putative uncharacterized protein; n=2; ... 42 0.061 UniRef50_Q8IB84 Cluster: Putative uncharacterized protein MAL8P1... 41 0.081 UniRef50_A5K2C4 Cluster: Phosphatidylcholine-sterol acyltransfer... 41 0.081 UniRef50_P53720 Cluster: tRNA-dihydrouridine synthase 2; n=7; Sa... 41 0.081 UniRef50_UPI0000E472BC Cluster: PREDICTED: similar to tRNA-dihyd... 41 0.11 UniRef50_Q755E8 Cluster: AFL125Wp; n=1; Eremothecium gossypii|Re... 41 0.11 UniRef50_Q1DPY5 Cluster: Putative uncharacterized protein; n=1; ... 41 0.11 UniRef50_A4S469 Cluster: Predicted protein; n=2; Ostreococcus|Re... 40 0.19 UniRef50_UPI00004991CC Cluster: hypothetical protein 205.t00005;... 40 0.25 UniRef50_Q5CYL0 Cluster: CDC68 like aminopeptidase family chroma... 40 0.25 UniRef50_Q24833 Cluster: Putative nitrogen fixation regulatory p... 40 0.25 UniRef50_A7EHJ6 Cluster: Putative uncharacterized protein; n=2; ... 40 0.25 UniRef50_O04650 Cluster: A_TM021B04.7 protein; n=2; Arabidopsis ... 39 0.33 UniRef50_Q7RI83 Cluster: CCAAT-box DNA binding protein subunit B... 39 0.33 UniRef50_A2FDS6 Cluster: Variable membrane protein, putative; n=... 39 0.33 UniRef50_A2EAT7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.33 UniRef50_Q4A6U3 Cluster: Putative uncharacterized protein; n=2; ... 39 0.43 UniRef50_Q31C98 Cluster: Putative uncharacterized protein precur... 39 0.43 UniRef50_Q54J63 Cluster: C2H2 type Zn finger-containing protein;... 39 0.43 UniRef50_Q2LEB7 Cluster: Jacob 6; n=3; Entamoeba invadens|Rep: J... 39 0.43 UniRef50_UPI00006CCCD3 Cluster: hypothetical protein TTHERM_0033... 38 0.57 UniRef50_UPI0000586CAD Cluster: PREDICTED: similar to Dus1l prot... 38 0.75 UniRef50_UPI000049A33F Cluster: hypothetical protein 476.t00003;... 38 0.75 UniRef50_Q9LH98 Cluster: Arabidopsis thaliana genomic DNA, chrom... 38 0.75 UniRef50_Q23AJ7 Cluster: Cyclic nucleotide-binding domain contai... 38 0.75 UniRef50_UPI00006CCA52 Cluster: TPR Domain containing protein; n... 38 0.99 UniRef50_Q7RLZ5 Cluster: CCAAT-box DNA binding protein subunit B... 38 0.99 UniRef50_Q7RBU8 Cluster: Putative uncharacterized protein PY0603... 38 0.99 UniRef50_Q54PB2 Cluster: RNA-binding region-containing protein; ... 38 0.99 UniRef50_Q8STA9 Cluster: UPF0329 protein ECU05_1680/ECU11_0050; ... 38 0.99 UniRef50_UPI0001509D27 Cluster: PHD-finger family protein; n=1; ... 37 1.3 UniRef50_UPI00004D6F7D Cluster: formin-like 2; n=3; Euteleostomi... 37 1.3 UniRef50_Q185D8 Cluster: Putative uncharacterized protein; n=2; ... 37 1.3 UniRef50_Q8IB22 Cluster: Putative uncharacterized protein MAL8P1... 37 1.3 UniRef50_Q5CG46 Cluster: Uncharacterized protein family UPF0034;... 37 1.3 UniRef50_Q4YYI6 Cluster: Ubiquitin-like protein, putative; n=3; ... 37 1.3 UniRef50_A0DRF5 Cluster: Chromosome undetermined scaffold_60, wh... 37 1.3 UniRef50_A0CXA4 Cluster: Chromosome undetermined scaffold_30, wh... 37 1.3 UniRef50_UPI00015B4E97 Cluster: PREDICTED: similar to conserved ... 37 1.7 UniRef50_UPI0000E49283 Cluster: PREDICTED: hypothetical protein;... 37 1.7 UniRef50_UPI0000D57222 Cluster: PREDICTED: similar to Transcript... 37 1.7 UniRef50_Q9LW95 Cluster: KED; n=3; cellular organisms|Rep: KED -... 37 1.7 UniRef50_Q8IDG7 Cluster: Putative uncharacterized protein PF13_0... 37 1.7 UniRef50_Q7RFV6 Cluster: GAF domain protein-related; n=1; Plasmo... 37 1.7 UniRef50_Q7RDM0 Cluster: Putative HSP protein; n=9; Plasmodium|R... 37 1.7 UniRef50_Q7RCW6 Cluster: CCAAT-box DNA binding protein subunit B... 37 1.7 UniRef50_Q7RBF2 Cluster: Guanylyl cyclase; n=2; Plasmodium (Vinc... 37 1.7 UniRef50_Q54Y92 Cluster: Developmental protein; n=2; Dictyosteli... 37 1.7 UniRef50_Q4Y6I2 Cluster: Putative uncharacterized protein; n=4; ... 37 1.7 UniRef50_A2FK59 Cluster: Putative uncharacterized protein; n=1; ... 37 1.7 UniRef50_A2EQX6 Cluster: Putative uncharacterized protein; n=1; ... 37 1.7 UniRef50_A2DRG2 Cluster: Putative uncharacterized protein; n=1; ... 37 1.7 UniRef50_Q5AFB2 Cluster: Putative uncharacterized protein UBR1; ... 37 1.7 UniRef50_UPI0000DA2A7E Cluster: PREDICTED: hypothetical protein;... 36 2.3 UniRef50_UPI00006CFFAC Cluster: hypothetical protein TTHERM_0072... 36 2.3 UniRef50_UPI0000499FFB Cluster: hypothetical protein 144.t00010;... 36 2.3 UniRef50_Q74RB1 Cluster: Putative uncharacterized protein; n=17;... 36 2.3 UniRef50_Q8IKY2 Cluster: Transcription factor IIIb subunit, puta... 36 2.3 UniRef50_Q7RNH1 Cluster: Putative uncharacterized protein PY0184... 36 2.3 UniRef50_Q54KW8 Cluster: Putative uncharacterized protein; n=2; ... 36 2.3 UniRef50_Q4Z5M6 Cluster: Putative uncharacterized protein; n=1; ... 36 2.3 UniRef50_Q4YUL1 Cluster: Putative uncharacterized protein; n=1; ... 36 2.3 UniRef50_A7RJ77 Cluster: Predicted protein; n=1; Nematostella ve... 36 2.3 UniRef50_A2DSC7 Cluster: Zinc finger, C2H2 type family protein; ... 36 2.3 UniRef50_Q6C1L3 Cluster: Similar to DEHA0C12419g Debaryomyces ha... 36 2.3 UniRef50_UPI0000E4938D Cluster: PREDICTED: similar to DnaJ domai... 36 3.0 UniRef50_UPI0000D56108 Cluster: PREDICTED: similar to CG18304-PA... 36 3.0 UniRef50_Q8I3L3 Cluster: Putative uncharacterized protein PFE125... 36 3.0 UniRef50_Q8I311 Cluster: Putative uncharacterized protein PFI069... 36 3.0 UniRef50_Q7RAX9 Cluster: Putative uncharacterized protein PY0637... 36 3.0 UniRef50_Q24FF9 Cluster: Putative uncharacterized protein; n=2; ... 36 3.0 UniRef50_A3FQA8 Cluster: ORF 73, contains large complex repeat C... 36 3.0 UniRef50_A2EBQ3 Cluster: Retinitis pigmentosa GTPase regulator-l... 36 3.0 UniRef50_A2EAT9 Cluster: Putative uncharacterized protein; n=1; ... 36 3.0 UniRef50_A0DQB8 Cluster: Chromosome undetermined scaffold_6, who... 36 3.0 UniRef50_A6RVV6 Cluster: Predicted protein; n=1; Botryotinia fuc... 36 3.0 UniRef50_A6UP05 Cluster: Putative uncharacterized protein; n=1; ... 36 3.0 UniRef50_UPI0000DB76E7 Cluster: PREDICTED: similar to activating... 36 4.0 UniRef50_UPI00006CFCA0 Cluster: 50S ribosomal protein; n=1; Tetr... 36 4.0 UniRef50_UPI00006CFC2B Cluster: hypothetical protein TTHERM_0053... 36 4.0 UniRef50_UPI00006CAF0F Cluster: hypothetical protein TTHERM_0068... 36 4.0 UniRef50_Q9U380 Cluster: Putative uncharacterized protein; n=2; ... 36 4.0 UniRef50_Q8I4Y4 Cluster: Putative uncharacterized protein; n=4; ... 36 4.0 UniRef50_Q8I3X5 Cluster: Putative uncharacterized protein PFE065... 36 4.0 UniRef50_Q6LF09 Cluster: Putative uncharacterized protein; n=6; ... 36 4.0 UniRef50_Q5WRA3 Cluster: Multidrug resistance associated protein... 36 4.0 UniRef50_Q54IN6 Cluster: Putative uncharacterized protein; n=1; ... 36 4.0 UniRef50_Q23DY9 Cluster: Cation channel family protein; n=2; Alv... 36 4.0 UniRef50_Q22VV7 Cluster: CHY zinc finger family protein; n=1; Te... 36 4.0 UniRef50_A2EVM3 Cluster: Viral A-type inclusion protein, putativ... 36 4.0 UniRef50_A2DCZ8 Cluster: Putative uncharacterized protein; n=1; ... 36 4.0 UniRef50_A0DA99 Cluster: Chromosome undetermined scaffold_43, wh... 36 4.0 UniRef50_Q8X0W5 Cluster: Related to micromolar calcium activated... 36 4.0 UniRef50_Q06704 Cluster: Golgin IMH1; n=2; Saccharomyces cerevis... 36 4.0 UniRef50_UPI00015B62AB Cluster: PREDICTED: similar to CG18255-PA... 35 5.3 UniRef50_UPI00015B4683 Cluster: PREDICTED: similar to step ii sp... 35 5.3 UniRef50_UPI0000D5659A Cluster: PREDICTED: similar to CG31716-PA... 35 5.3 UniRef50_UPI00006D0E10 Cluster: hypothetical protein TTHERM_0007... 35 5.3 UniRef50_UPI0000587834 Cluster: PREDICTED: hypothetical protein;... 35 5.3 UniRef50_Q9CDR2 Cluster: Putative uncharacterized protein ywdA; ... 35 5.3 UniRef50_Q4FME1 Cluster: Para-aminobenzoate synthase component I... 35 5.3 UniRef50_A2BXV3 Cluster: Putative uncharacterized protein; n=1; ... 35 5.3 UniRef50_Q0JLT4 Cluster: Os01g0572100 protein; n=4; Oryza sativa... 35 5.3 UniRef50_Q01CM9 Cluster: CCCH-type Zn-finger protein; n=2; Ostre... 35 5.3 UniRef50_Q8ILI4 Cluster: Putative uncharacterized protein; n=1; ... 35 5.3 UniRef50_Q54J55 Cluster: Myb domain-containing protein; n=1; Dic... 35 5.3 UniRef50_Q54DW3 Cluster: Putative uncharacterized protein; n=1; ... 35 5.3 UniRef50_Q4Q669 Cluster: Dihydrouridine synthase (Dus), putative... 35 5.3 UniRef50_Q23K98 Cluster: Cation channel family protein; n=1; Tet... 35 5.3 UniRef50_Q23CY3 Cluster: Putative uncharacterized protein; n=1; ... 35 5.3 UniRef50_Q17IV5 Cluster: Chromodomain helicase DNA binding prote... 35 5.3 UniRef50_A2FNC4 Cluster: Variable membrane protein, putative; n=... 35 5.3 UniRef50_A2FK26 Cluster: Putative uncharacterized protein; n=1; ... 35 5.3 UniRef50_A2FJY0 Cluster: Putative uncharacterized protein; n=1; ... 35 5.3 UniRef50_A2DU96 Cluster: Putative uncharacterized protein; n=1; ... 35 5.3 UniRef50_Q6CS59 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 35 5.3 UniRef50_Q9UTK5 Cluster: Abnormal long morphology protein 1; n=1... 35 5.3 UniRef50_UPI00015B4A86 Cluster: PREDICTED: similar to conserved ... 35 7.0 UniRef50_UPI0000E490A6 Cluster: PREDICTED: hypothetical protein;... 35 7.0 UniRef50_UPI0000D56C7E Cluster: PREDICTED: similar to 39 kDa FK5... 35 7.0 UniRef50_UPI00006CB399 Cluster: DnaJ domain containing protein; ... 35 7.0 UniRef50_UPI000069F7BF Cluster: UPI000069F7BF related cluster; n... 35 7.0 UniRef50_Q4V8V0 Cluster: Zgc:114130; n=2; Danio rerio|Rep: Zgc:1... 35 7.0 UniRef50_Q4UL48 Cluster: Putative uncharacterized protein; n=6; ... 35 7.0 UniRef50_Q4HEJ9 Cluster: Alpha-2,3-sialyltransferase; n=1; Campy... 35 7.0 UniRef50_A6DTT4 Cluster: Putative ABC transporter ATP-binding pr... 35 7.0 UniRef50_Q8I5K9 Cluster: Putative uncharacterized protein; n=6; ... 35 7.0 UniRef50_Q8I1P2 Cluster: Putative uncharacterized protein PFD094... 35 7.0 UniRef50_Q86AP2 Cluster: Similar to Plasmodium falciparum. Splic... 35 7.0 UniRef50_Q7RGK0 Cluster: Putative uncharacterized protein PY0434... 35 7.0 UniRef50_Q54BM0 Cluster: Putative uncharacterized protein; n=1; ... 35 7.0 UniRef50_Q4XNR6 Cluster: Putative uncharacterized protein; n=1; ... 35 7.0 UniRef50_Q4XNC6 Cluster: Putative uncharacterized protein; n=3; ... 35 7.0 UniRef50_Q24DC4 Cluster: Transporter/monovalent cation:proton an... 35 7.0 UniRef50_Q23DS1 Cluster: GTP-binding protein, putative; n=2; Euk... 35 7.0 UniRef50_Q236Y1 Cluster: Nucleolar protein,Nop52 containing prot... 35 7.0 UniRef50_Q22TK4 Cluster: Putative uncharacterized protein; n=1; ... 35 7.0 UniRef50_A7RXM0 Cluster: Predicted protein; n=1; Nematostella ve... 35 7.0 UniRef50_A2FQ26 Cluster: Putative uncharacterized protein; n=1; ... 35 7.0 UniRef50_A2DGN0 Cluster: Viral A-type inclusion protein, putativ... 35 7.0 UniRef50_A0C765 Cluster: Chromosome undetermined scaffold_154, w... 35 7.0 UniRef50_A6RSH0 Cluster: Putative uncharacterized protein; n=2; ... 35 7.0 UniRef50_P26651 Cluster: Tristetraproline; n=15; Eutheria|Rep: T... 35 7.0 UniRef50_Q20085 Cluster: Membrane-associated tyrosine- and threo... 35 7.0 UniRef50_UPI0000E4A60A Cluster: PREDICTED: hypothetical protein;... 34 9.3 UniRef50_UPI0000DB7261 Cluster: PREDICTED: similar to CG18304-PA... 34 9.3 UniRef50_UPI00006CD8C0 Cluster: hypothetical protein TTHERM_0052... 34 9.3 UniRef50_UPI0000519A67 Cluster: PREDICTED: similar to Calcium-bi... 34 9.3 UniRef50_UPI000065D2BF Cluster: Homolog of Homo sapiens "HT017; ... 34 9.3 UniRef50_Q7UWL4 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_Q7P5Y3 Cluster: Chromosomal replication initiator prote... 34 9.3 UniRef50_Q4ZHU1 Cluster: Biofilm-associated protein; n=7; Staphy... 34 9.3 UniRef50_Q1FF30 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_Q119V0 Cluster: Peptidase M23B; n=1; Trichodesmium eryt... 34 9.3 UniRef50_A5MYZ5 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_Q00VG0 Cluster: Homology to unknown gene; n=1; Ostreoco... 34 9.3 UniRef50_Q8IEC5 Cluster: Putative uncharacterized protein PF13_0... 34 9.3 UniRef50_Q7RP00 Cluster: Arabidopsis thaliana MXI22.1-related; n... 34 9.3 UniRef50_Q7RNC6 Cluster: KED, putative; n=3; Plasmodium (Vinckei... 34 9.3 UniRef50_Q7R9A9 Cluster: Drosophila melanogaster CG15040 gene pr... 34 9.3 UniRef50_Q6LF58 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_Q616H4 Cluster: Putative uncharacterized protein CBG152... 34 9.3 UniRef50_Q55AJ7 Cluster: Putative uncharacterized protein; n=2; ... 34 9.3 UniRef50_Q4Z510 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_Q23WL4 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_Q23FP7 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_Q23DL3 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_Q23AJ8 Cluster: Cyclic nucleotide-binding domain contai... 34 9.3 UniRef50_Q233W7 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_Q228K2 Cluster: SNF2 family N-terminal domain containin... 34 9.3 UniRef50_Q1ZXA6 Cluster: DNA repair protein Rad4 family protein;... 34 9.3 UniRef50_Q16WE5 Cluster: Translation initiation factor if-2; n=1... 34 9.3 UniRef50_O96179 Cluster: Putative uncharacterized protein PFB042... 34 9.3 UniRef50_A2EVV5 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_A2E8X0 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_A2DC69 Cluster: Glutamic acid-rich protein, putative; n... 34 9.3 UniRef50_A2DAK5 Cluster: Putative uncharacterized protein; n=1; ... 34 9.3 UniRef50_A0E9E1 Cluster: Chromosome undetermined scaffold_84, wh... 34 9.3 UniRef50_A0CMI7 Cluster: Chromosome undetermined scaffold_21, wh... 34 9.3 UniRef50_A0BVF0 Cluster: Chromosome undetermined scaffold_13, wh... 34 9.3 UniRef50_Q0TYL7 Cluster: Putative uncharacterized protein; n=2; ... 34 9.3 UniRef50_A6RH89 Cluster: Predicted protein; n=2; Ajellomyces cap... 34 9.3 UniRef50_A3LZ88 Cluster: Myosin-1; n=1; Pichia stipitis|Rep: Myo... 34 9.3 UniRef50_Q12499 Cluster: Nucleolar protein NOP58; n=5; Eukaryota... 34 9.3 >UniRef50_Q17M24 Cluster: tRNA-dihydrouridine synthase; n=1; Aedes aegypti|Rep: tRNA-dihydrouridine synthase - Aedes aegypti (Yellowfever mosquito) Length = 578 Score = 643 bits (1589), Expect = 0.0 Identities = 298/588 (50%), Positives = 408/588 (69%), Gaps = 18/588 (3%) Query: 8 VCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKNDSKTKK 67 VC IK E+++ + ++E EK+ D + A+ DN E K + + D K K Sbjct: 5 VCYIKPEFLVPR---VQE-----EKKPEDVTPAAKADNGTEEPPAK----KGRFDKKKKN 52 Query: 68 RGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFLNSKPKDIGDQ 127 RGQNK+R FK+ +++ C T+LD + + + C C+F HD ++F+ KPKDIG+ Sbjct: 53 RGQNKNRDLPFKEQDDARLCKTLLDGKLNSEK--CSNPRCRFSHDLERFIQLKPKDIGES 110 Query: 128 CHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTKNTLQPSLQTQLQKKKY 187 C++Y ++G C G+ CR+ H+ + N ++ + + L LQ QL+KK Y Sbjct: 111 CYIYSLKGYCNFGVTCRFAGAHLDEESNNKISEGIKREDHNLVSMCLSFDLQNQLRKKSY 170 Query: 188 NFDLAEKLVKHLDTRNKSVDKNLN-TSADVGEDIKIGAVTDEDLIKLLPRERKTIDWNNK 246 N+ A K++ + K + ++ +D + IG+ TDEDL+KL ERK I++ +K Sbjct: 171 NYSKANKIISKFERLQKESKEEVDGLGSDTLKAKPIGSCTDEDLVKLRSPERKKINFKDK 230 Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 LYLSPLTTVGNLPFRRICKE+G D+TCGEMA ++ G+ QEWAL KRH +EDLFG QI Sbjct: 231 LYLSPLTTVGNLPFRRICKEYGVDITCGEMACSVPIINGMMQEWALTKRHPSEDLFGVQI 290 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 CG+N +++ Q++ E+ ++DF+DLN+GCPIDLI+ +GGGS ++ R LE ++ S+ Sbjct: 291 CGHNQKLVSYATQVIAEHADVDFVDLNLGCPIDLIFNQGGGSALLRRRNILEVMIQSCSR 350 Query: 367 LLSI---PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 +L+ FTVK R G+Y +K + H +VPK WGASL+T+HGR++E RYTK +DW+YI Sbjct: 351 ILADYDKEFTVKTRMGIYANKYVAHELVPKFEEWGASLVTIHGRTKEQRYTKKADWDYIR 410 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDI 483 CAQ A P+YGNGDIF Y+DY++ ++ AP + GVM+GRGALIKPW+F EIKEQK D Sbjct: 411 QCAQQAKSIPIYGNGDIFCYQDYLDAKERAPELAGVMVGRGALIKPWVFQEIKEQKNLDP 470 Query: 484 SSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINER 543 SS +R ++LK+Y NYGLEHWGSDT+GVE+TRRFLLEW SFLYRYVP GLLERPPQ+IN+R Sbjct: 471 SSSERMDMLKRYVNYGLEHWGSDTKGVENTRRFLLEWQSFLYRYVPSGLLERPPQKINQR 530 Query: 544 PPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591 P + GRDDLETLMAS NC+DW+K+SEMLLGPVPD F F+PKHKANSY Sbjct: 531 PEAFRGRDDLETLMASPNCSDWVKLSEMLLGPVPDSFNFVPKHKANSY 578 >UniRef50_Q7PVV7 Cluster: ENSANGP00000016833; n=2; Endopterygota|Rep: ENSANGP00000016833 - Anopheles gambiae str. PEST Length = 594 Score = 641 bits (1583), Expect = 0.0 Identities = 315/603 (52%), Positives = 403/603 (66%), Gaps = 30/603 (4%) Query: 7 GVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIE-ITEDKNDSKT 65 G+C IK E+++ + IE K+ E K+D++S + KK ++E E+ K Sbjct: 4 GICHIKAEFLIPR---IEGKA---EDAKVDDTSEPPE------KKGRMEGNAEEPQGKKK 51 Query: 66 KKRGQNKSRPKIFKDGKESKPCPTILDVESSEQL-KICQYNNCKFIHDSKQFLNSKPKDI 124 K RGQNKSR FK+ + C ++LD E K C NC+F HD +FL KPKDI Sbjct: 52 KNRGQNKSRTVPFKEEDGLRLCKSLLDGNLGEDAAKKCTNANCRFSHDLDKFLQLKPKDI 111 Query: 125 GDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTKNTLQPSLQTQLQK 184 C++Y +G C G+ CR+ H+ + NI + L LQ L+K Sbjct: 112 DGTCYIYSTKGYCNFGVTCRFAGAHLDENRRNIYPEDFKPDTSMLVSTWLSTDLQHILRK 171 Query: 185 KKYNFDLAEKLVKHLDT-----RNKSVDKNLNTSADVGEDIK--------IGAVTDEDLI 231 +KYNF+ + K+V D +N+ N + + +D + GAVTDED+I Sbjct: 172 RKYNFNKSTKIVNKFDRLQQEEKNEKAKSNEQENGEAKDDAEQKPEESKPAGAVTDEDVI 231 Query: 232 KLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWA 291 KL ERK I + +KLYLSPLTTVGNLPFRRICKE+G D+TCGEMA ++ G QEWA Sbjct: 232 KLRSAERKRIVFRDKLYLSPLTTVGNLPFRRICKEYGVDITCGEMACAIPIINGAIQEWA 291 Query: 292 LVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM 351 L KRH +EDLFG Q+CG+NP ++T AQ++ E ++DFIDLN GCPIDLI+ +GGGS ++ Sbjct: 292 LTKRHSSEDLFGVQLCGHNPKLVTYAAQIIAEKADVDFIDLNTGCPIDLIFNQGGGSALL 351 Query: 352 HRLPALETSVRCASKLLSI---PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRS 408 R L+ V+ S+LL+ FTVK R G+Y +K I H +VPK +WGASLIT+HGR+ Sbjct: 352 RRQNVLKVMVQSCSRLLADYGKEFTVKTRIGIYNNKLIAHEMVPKFEDWGASLITIHGRT 411 Query: 409 REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIK 468 +E RYTK +DWEY++ CA A PV+GNGDIF YEDY +R P + GVM+GRGALIK Sbjct: 412 KEQRYTKRADWEYLQQCATQAQSVPVFGNGDIFGYEDYEHIRTKCPNIAGVMVGRGALIK 471 Query: 469 PWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYV 528 PW+F EIKE+K D SS +RFE+LK+Y NYGLEHWGSDT+GVE+TRRFLLEW SFLYRYV Sbjct: 472 PWVFQEIKERKTLDPSSGERFEMLKRYVNYGLEHWGSDTKGVETTRRFLLEWQSFLYRYV 531 Query: 529 PVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKA 588 P GLLERPPQRINERP Y GRDDLETLMAS NC DW+K+SEMLLGPVP+GF F+PKHKA Sbjct: 532 PYGLLERPPQRINERPDAYRGRDDLETLMASPNCNDWVKLSEMLLGPVPEGFNFVPKHKA 591 Query: 589 NSY 591 N+Y Sbjct: 592 NAY 594 >UniRef50_A7S213 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 570 Score = 620 bits (1531), Expect = e-176 Identities = 299/540 (55%), Positives = 379/540 (70%), Gaps = 17/540 (3%) Query: 55 EITEDKNDSKTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSK 114 E T+ K K RG N+ RP+ + SK C E + C Y HD + Sbjct: 40 EHTDGPPRKKKKNRGMNRQRPRDQRPDNSSKLCSFAARGEECTRGDSCFYG-----HDPQ 94 Query: 115 QFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTKNTL 174 +FL +K DIG +C + GKCP GI+CRY H TAD +I+N E F +K+DT N L Sbjct: 95 KFLETKEPDIGKECVNFLKSGKCPYGISCRYWKHHTTADLKSIINEEFFSHYKEDTSNNL 154 Query: 175 QPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGEDIKIGAVTDEDLIKLL 234 +Q L+KKKY F + ++ L +N+NT V G VT+EDLIKL Sbjct: 155 AKDVQISLRKKKYMFPRSNAYLELLSNA-----QNVNTQTGVVRTH--GCVTNEDLIKLR 207 Query: 235 PRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVK 294 +E+K ID+++KLYL+PLTT+GNLPFRRICK++GAD+TCGEMA+C +LL+G + EWALVK Sbjct: 208 TQEKKRIDFSDKLYLAPLTTIGNLPFRRICKQYGADITCGEMAMCTNLLQGQQSEWALVK 267 Query: 295 RHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRL 354 RH +ED+FG Q+CG P +TK A+LLQ+ T++DFID+N GCPIDL++ KG GS +M R Sbjct: 268 RHSSEDIFGVQLCGAFPDTMTKCAELLQKETDVDFIDINTGCPIDLVFNKGAGSALMERK 327 Query: 355 PALETSVRCASKLLSIPFTVKMRTGVYQDKKIT---HTIVPKMSNWGASLITVHGRSREA 411 L+ V+ ++ IP TVK+R G++ DKK T H +V + +WG ++T+HGRSRE Sbjct: 328 GKLQQIVQGMKSVIDIPLTVKIRAGIH-DKKYTWNAHKLVGNLRDWGTDMVTIHGRSREQ 386 Query: 412 RYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWI 471 RYTKS+DW+YI A+ A+P PV+GNGDI S+ED ++ RK A V GVMI RGA+IKPWI Sbjct: 387 RYTKSADWDYISEVAKLASPMPVFGNGDILSFEDAMQHRKQAG-VAGVMIARGAIIKPWI 445 Query: 472 FNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVG 531 F EIKEQ+ WDISS +R +IL+++ N GLEHWGSDTQGVE TRRFLLEWLSF RYVPVG Sbjct: 446 FTEIKEQRHWDISSSERLDILRQFVNAGLEHWGSDTQGVEKTRRFLLEWLSFTCRYVPVG 505 Query: 532 LLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591 LLER PQRIN+RPP YFGR+DLETLMAS NC DW+KISEMLLGPVP F FLPKHKANSY Sbjct: 506 LLERLPQRINDRPPAYFGRNDLETLMASPNCEDWVKISEMLLGPVPTTFAFLPKHKANSY 565 >UniRef50_Q9VIS4 Cluster: CG10463-PA; n=3; Sophophora|Rep: CG10463-PA - Drosophila melanogaster (Fruit fly) Length = 604 Score = 606 bits (1497), Expect = e-172 Identities = 301/617 (48%), Positives = 403/617 (65%), Gaps = 44/617 (7%) Query: 5 NAGVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKN-DS 63 ++G+C IK EY++ ++ + S D + +D ++E E K D Sbjct: 2 DSGICYIKPEYLVTEA---DGGSAAANTENSDTNKRKREDGG------EVEAGEKKKWDK 52 Query: 64 KTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFLNSKPKD 123 K +KRGQNK+RP +FKD + S C +++D E C NC+++HD +L +K +D Sbjct: 53 KERKRGQNKNRP-VFKDERYSHLCHSLIDGTGGEP---CSLANCRYVHDLDAYLAAKGED 108 Query: 124 IGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTK-NTLQPSLQTQL 182 +G +C+VY +G C RG++CR+ H G N+ RE +D+ T N + LQ +L Sbjct: 109 LGPECYVYTTKGYCARGVSCRFAKAHTDEQGRNL-KREDYDENAPPTTCNGVSSELQVRL 167 Query: 183 QKKKYNFDLAEKLVKHL----DTRN--KSVDKNLNTSADVGE----------------DI 220 +K +Y+F +++L+K D R + +K N S + GE D Sbjct: 168 RKHEYDFSRSKELIKMAEKLRDARKLKEQQEKEKNPSEETGEKQPSETTEILDAEKQTDT 227 Query: 221 K-----IGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGE 275 K G D+ I + +D+ KL LSPLTT+GNLPFRRICKEFGAD+TCGE Sbjct: 228 KSKPTATGCAIDDSAIGRDADHKPAVDFREKLVLSPLTTLGNLPFRRICKEFGADITCGE 287 Query: 276 MALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIG 335 MA + LLKG+ QEWAL KRH++ED+FG Q+CGNNP ++ + AQ++ E ++DFIDLNIG Sbjct: 288 MACAQPLLKGMGQEWALTKRHQSEDVFGVQLCGNNPNMLNQAAQVIHETAQVDFIDLNIG 347 Query: 336 CPIDLIYKKGGGSGMMHRLPALETSVR-CASKLLSIPFTVKMRTGVYQDKKITHTIVPKM 394 CPIDLIY++GGGS +M R LE +VR CA+ +PFTVKMRTG+Y DK + H ++P + Sbjct: 348 CPIDLIYQQGGGSALMRRTNILELTVRSCAALSDRLPFTVKMRTGIYADKSVAHELLPLV 407 Query: 395 SNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAP 454 WGAS +T+HGRSRE RYTK ++W YIE CA A PV GNGDI SYEDY+E R +AP Sbjct: 408 EEWGASAVTLHGRSREQRYTKHANWAYIEECAAKAKCMPVIGNGDILSYEDYMERRTLAP 467 Query: 455 TVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTR 514 V VMIGRGALIKPWIF EIKE++ W SS R+E+L+K+ NYGLEHWGSDT+GVE+TR Sbjct: 468 HVCSVMIGRGALIKPWIFQEIKEKQAWSPSSGQRYEMLQKFCNYGLEHWGSDTKGVETTR 527 Query: 515 RFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLG 574 RFLLEW SFLYRY+P L PPQ+IN RP Y GRD++ETLM+S N DW+K+SE LLG Sbjct: 528 RFLLEWQSFLYRYIPEALQTAPPQKINARPQKYRGRDEMETLMSSGNAADWVKLSESLLG 587 Query: 575 PVPDGFQFLPKHKANSY 591 VP+GF F+PKHKAN++ Sbjct: 588 RVPEGFTFVPKHKANAF 604 >UniRef50_Q96G46 Cluster: tRNA-dihydrouridine synthase 3-like; n=12; Eutheria|Rep: tRNA-dihydrouridine synthase 3-like - Homo sapiens (Human) Length = 650 Score = 586 bits (1446), Expect = e-166 Identities = 282/567 (49%), Positives = 383/567 (67%), Gaps = 36/567 (6%) Query: 55 EITEDKNDSKTKKR--GQNKSRPKIFKDGKE-SKPCPTILDVESSEQLKICQYNN-CKFI 110 E E +T+KR GQNK RP + + ++ CP+++ +++ C + + C+F+ Sbjct: 89 EAAEPGEQLQTQKRARGQNKGRPHVKPTNYDKNRLCPSLIQESAAK----CFFGDRCRFL 144 Query: 111 HDSKQFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKD-- 168 HD ++L +KP D+G +C +++ G+CP G+ CR+ H+ +G N+V E + Sbjct: 145 HDVGRYLETKPADLGPRCVLFETFGRCPYGVTCRFAGAHLRPEGQNLVQEELAARGTQPP 204 Query: 169 DTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLD------------TRNKSVDKNLN----- 211 +N L +LQ QL+K++ F+ AE+ ++ T + + N Sbjct: 205 SIRNGLDKALQQQLRKREVRFERAEQALRRFSQGPTPAAAVPEGTAAEGAPRQENCGAQQ 264 Query: 212 ------TSADVGEDIKI-GAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRIC 264 TS ++ G +TDED+++L P E+K +D KLYL+PLTT GNLPFRRIC Sbjct: 265 VPAGPGTSTPPSSPVRTCGPLTDEDVVRLRPCEKKRLDIRGKLYLAPLTTCGNLPFRRIC 324 Query: 265 KEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQEN 324 K FGADVTCGEMA+C +LL+G EWAL+KRH+ ED+FG Q+ G P +TK A+LL Sbjct: 325 KRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGAFPDTMTKCAELLSRT 384 Query: 325 TELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDK 384 E+DF+D+N+GCPIDL+YKKGGG +M+R + VR +++L +P TVK+RTGV + Sbjct: 385 VEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVRGMNQVLDVPLTVKIRTGVQERV 444 Query: 385 KITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444 + H ++P++ +WG +L+T+HGRSRE RYTK +DW+YIE C QAA+P P++GNGDI S+E Sbjct: 445 NLAHRLLPELRDWGVALVTLHGRSREQRYTKLADWQYIEECVQAASPMPLFGNGDILSFE 504 Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWG 504 D R + V G+MI RGAL+KPW+F EIKEQ+ WDISS +R +IL+ ++NYGLEHWG Sbjct: 505 D--ANRAMQTGVTGIMIARGALLKPWLFTEIKEQRHWDISSSERLDILRDFTNYGLEHWG 562 Query: 505 SDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTD 564 SDTQGVE TRRFLLEWLSFL RYVPVGLLER PQRINERPP Y GRD LETLMAS D Sbjct: 563 SDTQGVEKTRRFLLEWLSFLCRYVPVGLLERLPQRINERPPYYLGRDYLETLMASQKAAD 622 Query: 565 WIKISEMLLGPVPDGFQFLPKHKANSY 591 WI+ISEMLLGPVP F FLPKHKAN+Y Sbjct: 623 WIRISEMLLGPVPPSFAFLPKHKANAY 649 >UniRef50_Q91XI1 Cluster: tRNA-dihydrouridine synthase 3-like; n=7; Euteleostomi|Rep: tRNA-dihydrouridine synthase 3-like - Mus musculus (Mouse) Length = 637 Score = 583 bits (1439), Expect = e-165 Identities = 285/575 (49%), Positives = 380/575 (66%), Gaps = 34/575 (5%) Query: 44 DNNLEFKKTKIEITEDKNDSKTKKRGQNKSRPKIFKDGKESKP--CPTILDVESSEQLKI 101 ++ E KT++ I + + RGQNKSRP + K K CP+ L E Sbjct: 69 EDGQENGKTEVAIESRERQVPKRARGQNKSRPHV-KPAHYDKDRLCPSFLQ----EPATP 123 Query: 102 CQYNN-CKFIHDSKQFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNR 160 C + + C+F+HD ++L +KP D+G +C +++ G+CP + CR+ H+ +G N+V Sbjct: 124 CAFGDRCRFLHDVGRYLETKPADLGPRCVLFETFGRCPFSMTCRFAGAHLGPEGQNLVQE 183 Query: 161 EKFDQWKD--DTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLDT----------------- 201 E + +N L +LQ QL+K++ F+ AE+ + L Sbjct: 184 EVVARCAQLPSVRNGLDRALQQQLRKRQVCFERAEQALNRLTQSPMPTVVPETTVAMATP 243 Query: 202 RNKSVDKNLNTSADVGEDIK-----IGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVG 256 + S L+T G G +TDED+I+L P E+K +D + KLYL+PLTT G Sbjct: 244 KQNSCHAQLDTVGGAGTPQSSPVPTCGPLTDEDVIRLRPCEKKRLDISGKLYLAPLTTCG 303 Query: 257 NLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITK 316 NLPFRRICK FGADVTCGEMA+C +LL+G EWAL+KRH ED+FG Q+ G P +TK Sbjct: 304 NLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHPCEDIFGVQLEGAFPDTMTK 363 Query: 317 VAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKM 376 A+LL ++DF+D+N+GCPIDL+YKKGGG +M+R + VR + +L +P TVKM Sbjct: 364 CAELLNRTIDVDFVDINVGCPIDLVYKKGGGCALMNRSAKFQQIVRGVNGVLDVPLTVKM 423 Query: 377 RTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYG 436 RTGV + + H ++P++ +WG +L+T+HGRSRE RYT+ +DW YIE CA+ A+P P++G Sbjct: 424 RTGVQERVSLAHRLLPELRDWGVALVTLHGRSREQRYTRLADWPYIEQCAKVASPMPLFG 483 Query: 437 NGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYS 496 NGDI S+ED + V G+M+ RGAL+KPW+F EIKEQ+ WDISS +R +IL+ ++ Sbjct: 484 NGDILSFED--ANCAMQTGVAGIMVARGALLKPWLFTEIKEQRHWDISSSERLDILRDFT 541 Query: 497 NYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETL 556 +YGLEHWGSDTQGVE TRRFLLEWLSFL RYVPVGLLERPPQRINERPP Y GRD LETL Sbjct: 542 HYGLEHWGSDTQGVERTRRFLLEWLSFLCRYVPVGLLERPPQRINERPPYYLGRDYLETL 601 Query: 557 MASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591 MAS DWI+ISEMLLGPVP GF FLPKHKAN+Y Sbjct: 602 MASQQAADWIRISEMLLGPVPPGFVFLPKHKANAY 636 >UniRef50_UPI000058804E Cluster: PREDICTED: similar to MGC53781 protein; n=3; Deuterostomia|Rep: PREDICTED: similar to MGC53781 protein - Strongylocentrotus purpuratus Length = 655 Score = 549 bits (1356), Expect = e-155 Identities = 283/573 (49%), Positives = 370/573 (64%), Gaps = 52/573 (9%) Query: 64 KTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNN-CKFIHDSKQFLNSKPK 122 K K +GQNK R + E +PC L C++ + CKF HD ++ + K Sbjct: 89 KQKGKGQNKKRYREKTVPSEERPCLDFLRGAG------CRFGDKCKFSHDIQKLMAGKAP 142 Query: 123 DIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQW--KDDTKNTLQPSLQT 180 DI +C + G CP G+ CR+G HI + NIV+ EK + K +N L LQ Sbjct: 143 DINPRCINFDKFGSCPYGMLCRFGGAHIDDNLKNIVDEEKVKETGGKCVVRNLLSKDLQI 202 Query: 181 QLQKKKYNFDLAEKLVKHLDTRNKSVD---------KNLNTSADV-----GEDIK-IGAV 225 QL+K+ +F +++ ++ LDTR K + K+ N S V G+ G V Sbjct: 203 QLRKRNVHFKKSDQYMRTLDTRKKESNSKRPEGPGCKDHNESPTVVMPTSGDAHNHAGTV 262 Query: 226 TDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKG 285 TD D+IKL P E+K +D +KL L+PLTTVGNLPFR +CK+ GAD+TCGEMA+C +LL+G Sbjct: 263 TDADVIKLRPEEKKKLDVKDKLLLAPLTTVGNLPFRAVCKKLGADITCGEMAMCTNLLQG 322 Query: 286 LKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG 345 EWAL++RH +ED+FG Q+CG P +T+ A+LL + ++DFID+N+GCPIDL+Y KG Sbjct: 323 QSSEWALLRRHPSEDIFGVQLCGGFPDTMTRCAELLNDRLDIDFIDINVGCPIDLVYHKG 382 Query: 346 GGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVH 405 GSG+M+R+ + VR S +L IP TVKMRTGV+ D + H IV ++ +WGAS++TVH Sbjct: 383 AGSGLMNRMGKFQEIVRGMSSVLDIPLTVKMRTGVHNDNPVAHKIVRRIYDWGASVVTVH 442 Query: 406 GRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465 GR+RE RY+K +DW+Y++ C QAA P P GNGDI SYED R+ + G MI RGA Sbjct: 443 GRTREQRYSKLADWDYLKDCVQAADPHPFIGNGDILSYEDSNFFREQSGAT-GQMIARGA 501 Query: 466 LIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLY 525 LIKPWIF EIKEQ+ WDISS +RF+IL+ Y N GL HWGSD++GV TRRFLLEWLSFL+ Sbjct: 502 LIKPWIFTEIKEQRHWDISSSERFDILQDYINLGLLHWGSDSEGVRKTRRFLLEWLSFLH 561 Query: 526 RYVPVGLLERPPQRINERPPTYFGRDDLETLMASSN------------------------ 561 RY+PVGLLE PQ+INERPP Y GRDDLETLMAS+N Sbjct: 562 RYIPVGLLETLPQKINERPPYYVGRDDLETLMASANCADWVKIRPQLFVSHDNLENLMAS 621 Query: 562 --CTD-WIKISEMLLGPVPDGFQFLPKHKANSY 591 C + W+K+ EM LGPVPD FQFL KHKA+SY Sbjct: 622 ANCAEKWVKLREMFLGPVPDDFQFLAKHKASSY 654 >UniRef50_Q6PEH0 Cluster: Zgc:63779; n=8; Chordata|Rep: Zgc:63779 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 660 Score = 541 bits (1334), Expect = e-152 Identities = 253/438 (57%), Positives = 322/438 (73%), Gaps = 10/438 (2%) Query: 159 NREKFDQWKDDTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGE 218 + E+ +Q + +KNT QTQ ++ N ++ K + + KN + SA+ E Sbjct: 227 HEEQREQTDEQSKNTED---QTQTNNQRENANIQSKNTEDQRQSVEDPSKNGSDSANRRE 283 Query: 219 D----IK-IGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTC 273 IK IG +TD D+IKL P E+K +D+ +KLYL+PLTT GNLPFRR+CK FGAD+TC Sbjct: 284 TQVPPIKTIGPITDADIIKLRPCEKKQVDFRDKLYLAPLTTCGNLPFRRVCKRFGADITC 343 Query: 274 GEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLN 333 GEMA+C +LL+G EWAL+KRH +EDLFG Q+ G P +T+ A+LL +N ++DF+D+N Sbjct: 344 GEMAMCTNLLQGQASEWALLKRHASEDLFGVQLEGCFPDTMTRCAELLNQNIDVDFVDIN 403 Query: 334 IGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPK 393 GCPIDL+YKKGGG G+M R E VR + +L +P TVK+RTGV Q+ I H ++P+ Sbjct: 404 SGCPIDLVYKKGGGCGLMTRTSKFEQIVRGMNSVLDVPLTVKIRTGVQQNSNIAHKLIPE 463 Query: 394 MSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIA 453 M WG SLIT+HGRSRE RYTK +DW+YI TCAQ A P P++GNGDI SYED ++ R+ Sbjct: 464 MKKWGVSLITLHGRSREQRYTKLADWDYINTCAQLAAPVPLFGNGDILSYEDAMKARETG 523 Query: 454 PTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVEST 513 V G+M+ RGALIKPW+F EIKE + WDISS +R +IL+ ++++GLEHWGSDTQGVE T Sbjct: 524 --VSGIMVARGALIKPWLFTEIKESRHWDISSTERLDILRDFTHFGLEHWGSDTQGVEKT 581 Query: 514 RRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLL 573 R FLLEWLSFL RY+PVGLLER PQRINERPP Y GRD LETLMAS + DWI+ISEMLL Sbjct: 582 RNFLLEWLSFLCRYIPVGLLERVPQRINERPPFYMGRDYLETLMASQHVDDWIQISEMLL 641 Query: 574 GPVPDGFQFLPKHKANSY 591 GPVP F FLPKHKAN+Y Sbjct: 642 GPVPKNFSFLPKHKANAY 659 Score = 120 bits (290), Expect = 8e-26 Identities = 70/200 (35%), Positives = 105/200 (52%), Gaps = 14/200 (7%) Query: 7 GVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEI---TEDKNDS 63 G AIK +++ K E S +K +E D E KK ++E T ++ Sbjct: 11 GAAAIKSQFLTSKEKFHEFLSSGRSSQKNEEDP---DGGEPEKKKIRLENEGETAEQEKK 67 Query: 64 KTKKRGQNKSRPKIFKDGKESKP-CPTILDVESSEQLKICQYNN-CKFIHDSKQFLNSKP 121 K K RGQNKSRP + E K C +I+ S +C Y C+F+HD ++L++K Sbjct: 68 KIKMRGQNKSRPHVKPHTYEDKRLCTSIIQERDS----VCPYGEKCRFLHDVSEYLSTKA 123 Query: 122 KDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKF--DQWKDDTKNTLQPSLQ 179 D+GDQCH++ GKCP G+ CRY H +AD N+VN E + +++T N L LQ Sbjct: 124 ADLGDQCHLFNTLGKCPYGLTCRYAKAHTSADLKNMVNTELYRASAGRENTTNLLDKELQ 183 Query: 180 TQLQKKKYNFDLAEKLVKHL 199 +L+KK+ F A+ +K + Sbjct: 184 KRLRKKQQRFPGADAFLKSI 203 >UniRef50_A4RQU5 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 608 Score = 489 bits (1206), Expect = e-137 Identities = 239/538 (44%), Positives = 336/538 (62%), Gaps = 18/538 (3%) Query: 69 GQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFLNSKPKDIGDQC 128 G R K + + KP L + + + K + CK+ HD FL +KP D+ C Sbjct: 60 GAFNKRAKFAEKSRADKPRERGLCNQLTREGKCAFGDACKYSHDVDAFLKTKPPDLPGTC 119 Query: 129 HVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTK------NTLQPSLQTQL 182 G CP G+ CRY H T +G + + + K N + + +L Sbjct: 120 TFVNKEGGCPYGVRCRYYGTHATGEGRDGATVAESTTTLEPPKTVEKEMNFVDKDVMVRL 179 Query: 183 QKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGEDIKIGAVTDED------LIKLLPR 236 +KKKY+F A+ +VK + R K+ T A K V +E+ K Sbjct: 180 RKKKYDFSRADTIVKEV-LRAMETKKDEQTKAGEESAAKRAKVDEENRTDTGAFTKARVE 238 Query: 237 ERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRH 296 E++TID+ +KLYL+PLTTVGNLPFRR+CK GAD+TCGEMALC SLL+GL EWAL++RH Sbjct: 239 EKRTIDFKDKLYLAPLTTVGNLPFRRVCKTLGADITCGEMALCTSLLQGLPSEWALLRRH 298 Query: 297 ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPA 356 ++ED+FG QICG P +T+ QLL++ ++DFID+N+GCPID + +KG GS M+ + Sbjct: 299 KSEDIFGVQICGGYPDSVTRCCQLLEDTIDVDFIDINMGCPIDSVCQKGYGSMMLEKPKK 358 Query: 357 LETSVRCASKLL-SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTK 415 +ET +R AS L T K R ++ HT PK++ WGA+ +T+HGR+R RY Sbjct: 359 METVIRAASAALGKCSLTFKTRMAYTDKSRVAHTFAPKVAEWGAAAMTLHGRTRAQRYRS 418 Query: 416 SSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 +DWEY + ++++ P+ GNGD++ +DY + +V M+ RGALIKPW+F EI Sbjct: 419 VADWEYTKLTKESSS-VPLIGNGDVYMQKDYYTHLE-EHSVDTCMLARGALIKPWLFTEI 476 Query: 476 KEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLER 535 KE++ WDISS++RF+ILK ++++GLEHWGSDT+GVESTR++LLEW+SF YRY P+GLL+ Sbjct: 477 KERRDWDISSRERFDILKSFASFGLEHWGSDTRGVESTRKYLLEWMSFTYRYTPIGLLDH 536 Query: 536 P--PQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591 + +RPP + GRDDLETLMAS +DW+KIS MLLGP P+GF F PKHK+N+Y Sbjct: 537 SYGAAAMTQRPPAFVGRDDLETLMASEASSDWVKISTMLLGPPPEGFAFQPKHKSNAY 594 >UniRef50_UPI00015B6197 Cluster: PREDICTED: similar to CG10463-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CG10463-PA - Nasonia vitripennis Length = 584 Score = 483 bits (1192), Expect = e-135 Identities = 246/494 (49%), Positives = 319/494 (64%), Gaps = 36/494 (7%) Query: 6 AGVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKNDSKT 65 +GVC +K EY+++ S E N K K E + + D + + K + E+K D Sbjct: 23 SGVCLVKPEYIIEDSVRSNENGTN-GKGKDTEKTETDADAAEDGEPPKKKFKENKKD--- 78 Query: 66 KKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFLNSKPKDIG 125 K RGQNK R FK +E CP I D+ E K C NNC FIHD ++L KP DIG Sbjct: 79 KPRGQNKGRSVPFKTQREHNLCPWIADLTVEEVEKKCSNNNCHFIHDRAEYLKIKPDDIG 138 Query: 126 DQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKD---DTKNTLQPSLQTQL 182 +C+V+++ GKCPRG ACR GS H T DGFNI+++EKF+ + TKN + L +L Sbjct: 139 TECYVFELTGKCPRGAACRMGSKHTTPDGFNIIDKEKFEAYTKLPPSTKNQISRELSEKL 198 Query: 183 QK------------KKYNF---DLAEKLVKHLDTRNKSV----DKNLNTSADVGEDI--- 220 +K KK+N+ +L +K T+ DK+ D Sbjct: 199 KKYKYNFAKAEKIAKKHNWKSNELFDKSKSQNPTKTPETTQIPDKSETPQTPEKSDTLQT 258 Query: 221 -------KIGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTC 273 K+G + D D IKL P E+K IDW +K+ L+PLTTVGNLPFRRICKEFGAD+TC Sbjct: 259 PEKPKEEKVGPILDTDEIKLHPDEKKKIDWKDKIMLAPLTTVGNLPFRRICKEFGADITC 318 Query: 274 GEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLN 333 GEMAL LLKG+++EWALVKRHE+EDLFG QI GNNP ++T+ QLL + TE+DF+DLN Sbjct: 319 GEMALAPRLLKGVREEWALVKRHESEDLFGVQIAGNNPGVLTRCCQLLNDETEVDFVDLN 378 Query: 334 IGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPK 393 +GCPIDL+YK+GGG GM++RL LE+ V+ A+++L IPFTVK RTGVY DK I H ++ K Sbjct: 379 VGCPIDLVYKQGGGCGMLNRLNILESVVKSATEVLDIPFTVKTRTGVYADKPIAHKLMSK 438 Query: 394 MSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIA 453 +WGAS+I +HGRSRE RYTK +DW+YIE CAQ A+P PVYG GDI S++DY +RK Sbjct: 439 FKDWGASMINIHGRSREQRYTKLADWDYIEKCAQVASPIPVYGTGDILSWDDYQRVRKTY 498 Query: 454 PTVKGVMIGRGALI 467 PTV+GV I RGALI Sbjct: 499 PTVQGVSIARGALI 512 Score = 121 bits (291), Expect = 6e-26 Identities = 57/84 (67%), Positives = 63/84 (75%), Gaps = 2/84 (2%) Query: 508 QGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIK 567 QGV R L+ YVPVG+L PPQR+N RPP Y GRDDLETLMASSNC DWIK Sbjct: 502 QGVSIARGALIX--XXXXXYVPVGILVEPPQRMNNRPPYYRGRDDLETLMASSNCADWIK 559 Query: 568 ISEMLLGPVPDGFQFLPKHKANSY 591 +SEMLLG VPDGF FLPKHKAN++ Sbjct: 560 LSEMLLGKVPDGFNFLPKHKANAW 583 >UniRef50_Q9TYN2 Cluster: Putative uncharacterized protein Y37E11B.5; n=2; Caenorhabditis|Rep: Putative uncharacterized protein Y37E11B.5 - Caenorhabditis elegans Length = 554 Score = 455 bits (1121), Expect = e-126 Identities = 238/535 (44%), Positives = 331/535 (61%), Gaps = 25/535 (4%) Query: 64 KTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYNN-CKFIHDSKQFLNSKPK 122 K ++RG NK+R K K + + S Q C++ C HD FL KP Sbjct: 38 KRERRGMNKTRRKDMKHAETRIRAAAVRLCPSVIQPVACKFGEKCNCEHDISAFLAKKPA 97 Query: 123 DIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTKNTLQPSLQTQL 182 DIG C +Y RG CP ACR+G H+ G + + ++ + T N +Q L Sbjct: 98 DIGVACPLYDARGACPFSYACRFGGAHLDEAGQQ--SEKSPEKPYEPTTNCHSMKIQVAL 155 Query: 183 QKKKYNFDLAEKLVKHLDTRNKSV-DKNLNTSADVGEDIKIGAVTDEDLIKLLPRERKTI 241 +K++Y+F+ EK ++ + N V + +L+T +GA+ E P ++ Sbjct: 156 RKREYDFEKTEKALEAIKNENFEVLELSLST---------VGAMCREKK----PLNMGSL 202 Query: 242 DWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDL 301 D K YL+PLTTVGNLPFRRIC ++GAD+TCGEMAL S+L G E++L+KRH E + Sbjct: 203 D--GKKYLAPLTTVGNLPFRRICVDYGADITCGEMALATSILSGTASEYSLLKRHPCEKI 260 Query: 302 FGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361 FG Q+ G + K +Q++ EN ++DFID+N+GCPID++ +KGGG + R L + Sbjct: 261 FGVQLAGGFADTMAKASQIVVENFDVDFIDINMGCPIDVVNQKGGGCALPSRPQKLFEVL 320 Query: 362 RCASKLLS--IPFTVKMRTGVYQD--KKITHTIVPKMSNWGA-SLITVHGRSREARYTKS 416 +L P TVK+RTG+ + K + K +W LIT H RS+E RYT+ Sbjct: 321 AATKSVLGGCCPLTVKIRTGMKEGVLKAPEYVEHMKKHSWHTPDLITFHPRSKEQRYTRL 380 Query: 417 SDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 ++W++ +A P P++ GDI S+EDY E + P V G+MIGRGALIKPWIF EI Sbjct: 381 ANWDFTFPVQEATKPVPLWVCGDILSWEDYYERLEQYP-VNGIMIGRGALIKPWIFTEID 439 Query: 477 EQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERP 536 E++ WDISS +RF++LKK+ +YGL+HWGSD GVE TRRFLLE+LSF RY+PVG+LER Sbjct: 440 ERRTWDISSTERFDLLKKFVDYGLDHWGSDDAGVERTRRFLLEFLSFQCRYIPVGILERL 499 Query: 537 PQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591 PQRIN+RPP + GR++LETL++S DWI+IS LLGP P+GFQF+PKHKA+SY Sbjct: 500 PQRINDRPPRFCGRNELETLLSSQKADDWIEISTRLLGPTPEGFQFIPKHKASSY 554 >UniRef50_Q01ML2 Cluster: H0613H07.1 protein; n=10; Eukaryota|Rep: H0613H07.1 protein - Oryza sativa (Rice) Length = 685 Score = 451 bits (1111), Expect = e-125 Identities = 209/394 (53%), Positives = 277/394 (70%), Gaps = 3/394 (0%) Query: 199 LDTRNKSVDKNLNTSADVGEDIKIGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNL 258 L+T +S D NL+ + + TD L RE+K ID+ KLYL+PLTTVGNL Sbjct: 288 LNTNTESEDPNLSNGLEPSNNAS-SCRTDLITTPHL-REKKIIDFREKLYLAPLTTVGNL 345 Query: 259 PFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVA 318 PFRR+CK GAD+TCGEMA+C +LL+G EWAL++RH +EDLFG QICG P + + Sbjct: 346 PFRRLCKTLGADITCGEMAMCTNLLQGQASEWALLRRHSSEDLFGVQICGAYPDTVARTV 405 Query: 319 QLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRT 378 +L+ +DFID+N+GCPID++ KG GS ++ + +++ V+ AS + P TVK+RT Sbjct: 406 ELVDNECSVDFIDINMGCPIDIVVNKGAGSSLLTKPMRIKSIVQAASTVTEKPLTVKVRT 465 Query: 379 GVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ-AATPCPVYGN 437 ++ + +IV + +WGAS ITVHGRSR+ RY+K +DW+YI CAQ A V GN Sbjct: 466 AFFEGRNRADSIVSDIYDWGASAITVHGRSRQQRYSKLADWDYIYQCAQKAPDQLHVVGN 525 Query: 438 GDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSN 497 GD+FS+ D+ + + MI RGALIKPWIF E+KEQ+ WDI+S +RF ILK + Sbjct: 526 GDVFSFTDWNKHVSGCSKISTCMIARGALIKPWIFTEVKEQRHWDITSGERFNILKDFVT 585 Query: 498 YGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLM 557 +GLEHWGSD++GVE+TR FLLEWLS+ RY+PVGLL+ PQR+N RPP+Y GRDDLETLM Sbjct: 586 FGLEHWGSDSKGVETTRYFLLEWLSYTCRYIPVGLLDVIPQRLNWRPPSYCGRDDLETLM 645 Query: 558 ASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591 S + DWI+ISEMLLG VP+GF F PKHK+N+Y Sbjct: 646 ISDSAADWIRISEMLLGKVPEGFTFTPKHKSNAY 679 Score = 54.8 bits (126), Expect = 6e-06 Identities = 42/157 (26%), Positives = 68/157 (43%), Gaps = 15/157 (9%) Query: 70 QNKSRPKIFKDGKESKPCPTILDVE--SSEQLKICQY-NNCKFIHDSKQFLNSKPKDIGD 126 + KS+ ++ ++ K+ + + L +E S + C+Y ++C+F HD +L KP D+ Sbjct: 71 EKKSKRQLKRERKQEQKSSSHLCIEVGKSGNVSSCKYGDSCRFSHDIDAYLAQKPADLEG 130 Query: 127 QCHVYKVRGKCPRGIACRYGSDH--ITADGFNIVNREKFDQWKDDTKNTLQPSLQTQLQK 184 C + CP G+ CR+ H I A N+ + + N L +Q L K Sbjct: 131 TCPFTNLDQLCPYGLTCRFLGTHKDIHAASGNLSEKHEI--------NALNKDIQKLLWK 182 Query: 185 KKYNFDLAEKLVKHLDTRN--KSVDKNLNTSADVGED 219 KY F A +K L + KS N V D Sbjct: 183 NKYKFPKASAQIKLLGLKEVIKSKPDAANDDKKVNHD 219 >UniRef50_Q582L4 Cluster: TRNA-dihydrouridine synthase 3, putative; n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 3, putative - Trypanosoma brucei Length = 528 Score = 418 bits (1030), Expect = e-115 Identities = 208/437 (47%), Positives = 281/437 (64%), Gaps = 10/437 (2%) Query: 157 IVNREKFDQWKDDTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADV 216 +V ++ D +D ++ PS + + K D E+ L N + ++ + V Sbjct: 85 VVRGKRKDTKRDRREDCQAPSGEAESTAGKVKHDDEERGTPALQQTNTD-ESHITVKSAV 143 Query: 217 GEDIKIGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEM 276 A E+ ++ + K + ++NKL L+PLTTVGNLPFRR+CKE+GAD+T GEM Sbjct: 144 AR-----ASNTEESMRERSAQHKAL-FSNKLVLAPLTTVGNLPFRRVCKEYGADITVGEM 197 Query: 277 ALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENT-ELDFIDLNIG 335 A+ +L + K EW+L++RH +ED+FG QI + P+ AQ ++E+ DF+D+N G Sbjct: 198 AIVHNLNRLQKSEWSLLRRHSSEDIFGLQIAVSRPHDAITWAQAVEESGFSYDFVDINCG 257 Query: 336 CPIDLIYKKGGGSGMMHRLP-ALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKM 394 CP+D + G G G+ R L V+ S P T+K R G ++ H + Sbjct: 258 CPVDKVVLSGCGCGLWERKGNRLRDVVQSLVAHQSKPVTIKCRMGPDEENPELHKHIADY 317 Query: 395 SNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAP 454 WGA+ +T+HGRSR RYTK ++W YI+ CA + T PV GNGDIFS ED VE R + Sbjct: 318 ETWGAAAVTIHGRSRRQRYTKLANWSYIDNCA-SLTSLPVIGNGDIFSCEDIVEHRAQSK 376 Query: 455 TVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTR 514 V MIGRGAL+KPWIF EIK ++WDISS +RFE+L+++ N+GL HWG+D +GV +TR Sbjct: 377 NVSSFMIGRGALVKPWIFEEIKTGRVWDISSHERFEMLRRFCNFGLSHWGADERGVLNTR 436 Query: 515 RFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLG 574 RFL EWLSFL RYVPVGLLERPPQRINERPP Y GRD+LETLMAS + DWI+ISEMLLG Sbjct: 437 RFLCEWLSFLCRYVPVGLLERPPQRINERPPYYEGRDELETLMASDSAVDWIRISEMLLG 496 Query: 575 PVPDGFQFLPKHKANSY 591 P D F+F PKHK+N+Y Sbjct: 497 PAGDKFRFTPKHKSNAY 513 >UniRef50_Q54CU9 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 671 Score = 415 bits (1023), Expect = e-114 Identities = 189/391 (48%), Positives = 266/391 (68%), Gaps = 4/391 (1%) Query: 202 RNKSVDKNLNTSADVGEDIKIGAVTDEDLIK-LLPRERKTIDWNNKLYLSPLTTVGNLPF 260 + + +K T E + T+ D++ L E+K I++ N+L L+PLTTVGNLPF Sbjct: 280 KTEKTEKTETTETKKEEFKQSNENTEIDIMTPLKANEKKRINFENQLILAPLTTVGNLPF 339 Query: 261 RRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQL 320 RRICK GAD+T GEMAL LL+G K E AL+KRH ED FG QICG+ K A+ Sbjct: 340 RRICKRLGADITIGEMALTTKLLEGTKSELALLKRHPCEDKFGVQICGSYVDAAVKCAEF 399 Query: 321 LQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGV 380 ++ + DF+D+N GCPIDL+ G G+ +M R +E +R S LS P T+K+R G Sbjct: 400 IENEIDADFVDINSGCPIDLVCNMGAGAALMERPKKVEQLLRGISSSLSCPTTIKIRIGK 459 Query: 381 YQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDI 440 +D H ++P + WGA +T+HGRSR RY++ ++W+Y++ C++ ++ P+ GNGDI Sbjct: 460 SEDAPTAHKLIPSLGEWGACAVTLHGRSRAQRYSRLANWDYVKQCSEVSS-IPLIGNGDI 518 Query: 441 FSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGL 500 ++Y+D V + + V +MI RGALIKPWIF EIKE++ WDIS+ +R + ++ ++NYGL Sbjct: 519 YNYQDVVNIYD-SSKVSSIMIARGALIKPWIFTEIKEKREWDISASERLDFIRDFANYGL 577 Query: 501 EHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASS 560 +HWGSD GV++TR+FLL WLSF +RY+PVGLL++ +NERPP YFGR DLETL+AS+ Sbjct: 578 DHWGSDRIGVDNTRKFLLNWLSFSHRYIPVGLLDK-VHYMNERPPAYFGRSDLETLLAST 636 Query: 561 NCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591 DWIKI+EM LGPV + F+PKH +NSY Sbjct: 637 QVKDWIKITEMFLGPVTSDYSFVPKHNSNSY 667 Score = 69.3 bits (162), Expect = 3e-10 Identities = 59/179 (32%), Positives = 87/179 (48%), Gaps = 27/179 (15%) Query: 47 LEFKKT-KIEITEDKNDSKTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYN 105 L FKK K+E+ DK K + R Q ++ K CP I S+ L +C++N Sbjct: 73 LPFKKIEKVEV--DKAAKKKEFRNQ-------LRESMNDKLCPKI-----SKGL-VCEFN 117 Query: 106 N-CKFIHDSKQFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFD 164 CKF HD +++L SKPK IG C ++ G+C G+ C +G HI D IVN+E Sbjct: 118 ETCKFSHDVEKYLASKPKSIG-ICQNFQTYGECKYGLNCYFGECHI-VDNKTIVNKELIG 175 Query: 165 QWKD-DTKNTLQPSLQTQLQKKKYNFDLAEKL-------VKHLDTRNKSVDKNLNTSAD 215 + + T N + +Q QL+ Y F +E V+ + RN + +KN N D Sbjct: 176 KVEPVKTLNEVSNEIQIQLKTNNYPFPKSEIYFNENGISVRQIKGRNNNNNKNNNKQND 234 >UniRef50_Q010A0 Cluster: tRNA-dihydrouridine synthase; n=1; Ostreococcus tauri|Rep: tRNA-dihydrouridine synthase - Ostreococcus tauri Length = 639 Score = 410 bits (1009), Expect = e-113 Identities = 209/505 (41%), Positives = 312/505 (61%), Gaps = 26/505 (5%) Query: 98 QLKICQYNN-CKFIHDSKQFLNSKPKDIGDQCHVY--KVRGKCPRGIACRYGSDHITADG 154 Q ++C+ C + HD + SKP D+ V+ CP G+ CR+ S H Sbjct: 131 QGEVCRLGKRCGYSHDLSAYRASKPSDVERAACVFINAESDSCPFGVRCRFESSH----- 185 Query: 155 FNIVNREKFDQWKDDTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSA 214 + K D+ + N L ++Q +L + +Y F ++K ++ N V K L+ + Sbjct: 186 ----RKMKSDKTVEMPMNILDDAMQKRLSRNEYPFPRSDKALRE---GNLEV-KCLSFAQ 237 Query: 215 DVGEDIKIGAVTDEDLIKLLPRERK-TIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTC 273 D + G + + ++ RE++ ++++ K+Y++PLTTVGNLPFRRIC + GAD+T Sbjct: 238 KHKLDRREGFLGSFEPGRVNAREKRVSLEFKGKIYVAPLTTVGNLPFRRICTDLGADITV 297 Query: 274 GEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLN 333 EMA+ +LLKG ++EWALV+RH E FG QICG P ++T+ A+LL DFID+N Sbjct: 298 SEMAMASNLLKGDRKEWALVRRHPIEKCFGIQICGGYPDLMTRCAELLDNEVHCDFIDVN 357 Query: 334 IGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQD--KKITHTIV 391 +GCPID + KG G +M L+ VR + + S P T+K+R G + D + + H I+ Sbjct: 358 MGCPIDGVCAKGAGGSLMRDTDRLKRVVRSMTSVSSTPVTIKLRMGYFDDPSRYVAHDII 417 Query: 392 PKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA--TPCPVYGNGDIFSYEDYVEM 449 K +WGA T+HGR+RE RY++ +DW YI CA A+ P+ GNGD+++Y+D+ E Sbjct: 418 SKAKSWGAYAATLHGRTREQRYSRLADWSYIHRCADASALNNLPLIGNGDVYTYQDWNE- 476 Query: 450 RKIA-PTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQ 508 +IA + MIGRGA+IKPW+ EIKEQ+ WDIS+ +R ++ K + +YGLEHWGSD+ Sbjct: 477 -QIANEKISTCMIGRGAIIKPWLMTEIKEQRHWDISANERLDLFKDFVHYGLEHWGSDSV 535 Query: 509 GVESTRRFLLEWLSFLYRYVPVGLLER-PPQRINERPPTYFGRDDLETLMASSNCTDWIK 567 GVE TRR+LLEW+S+ +RYVP+GLLE+ +++ RP Y GR DLET +AS DW++ Sbjct: 536 GVEKTRRYLLEWMSYTHRYVPIGLLEQNVVPKLHLRPMRYVGRSDLETKLASDKLEDWLE 595 Query: 568 ISEML-LGPVPDGFQFLPKHKANSY 591 +SE+ LG F+F+PKH +NSY Sbjct: 596 LSELSGLGKPDPSFRFVPKHASNSY 620 >UniRef50_Q5KC68 Cluster: TRNA dihydrouridine synthase, putative; n=2; Filobasidiella neoformans|Rep: TRNA dihydrouridine synthase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 725 Score = 407 bits (1003), Expect = e-112 Identities = 190/376 (50%), Positives = 259/376 (68%), Gaps = 16/376 (4%) Query: 231 IKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEW 290 + L P E++ ++W YL+PLTTVGNLPFRR+C ++GA +T EMAL + L+ G K+EW Sbjct: 344 VPLRPEEKRRLNWEGGRYLAPLTTVGNLPFRRLCVDYGATITVSEMALAQPLVYGAKEEW 403 Query: 291 ALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTE----LDFIDLNIGCPIDLIYKKGG 346 ALV+RHE+E +FG Q+ G P + A+++ +DF+D+N+GCPIDL++ +G Sbjct: 404 ALVRRHESEKMFGVQVAGGFPNRMVPAAEVIANTIGKGGGVDFVDVNMGCPIDLVFNQGA 463 Query: 347 GSGMMHRLPALETSVRCASKLLS-IPFTVKMRTGVYQDKKITHTIVPK-MSNWGASLITV 404 GS +M L + ++ L IP TVK RTGV K H ++P+ ++ WGA +T+ Sbjct: 464 GSALMDSPGRLGKLLVGMNRALGDIPLTVKFRTGVAHGKPNAHKLIPRFVTEWGAGALTI 523 Query: 405 HGRSREARYTKSSDWEYIETCAQAAT---------PCPVYGNGDIFSYEDYVEMRKIAPT 455 HGRSR+ RY+K +DWEYI+TC A P P++GNGD FS Y E + Sbjct: 524 HGRSRQQRYSKPADWEYIKTCVTALRESVADANLPPVPIFGNGDCFSAASYYEEMDRSG- 582 Query: 456 VKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRR 515 V GVM+ RGALIKPWIF EIKE++ WDIS+ +R E +KK++ +GL HWGSDTQGV +TRR Sbjct: 583 VDGVMVARGALIKPWIFTEIKERREWDISAVERLEGIKKFAEFGLSHWGSDTQGVNTTRR 642 Query: 516 FLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGP 575 FL E LSF +RY+P+GLLER P ++NERPP Y GR++LETL+AS DW+KISEM LG Sbjct: 643 FLCEALSFQHRYIPIGLLERLPAKLNERPPAYRGRNELETLLASPFAGDWVKISEMFLGK 702 Query: 576 VPDGFQFLPKHKANSY 591 V +GF F+PKHK+N+Y Sbjct: 703 VDEGFSFVPKHKSNAY 718 >UniRef50_Q4QEF9 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania major Length = 595 Score = 404 bits (994), Expect = e-111 Identities = 193/368 (52%), Positives = 256/368 (69%), Gaps = 3/368 (0%) Query: 226 TDEDLIKLLPRERKTID-WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK 284 T+E L +++ R+ + + KL L+PLTTVGNLPFRRICK FGADVT EMA+ +L + Sbjct: 215 TEESLREVIARQSSSRGLFAEKLVLAPLTTVGNLPFRRICKSFGADVTLSEMAVVFNLNR 274 Query: 285 GLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENT-ELDFIDLNIGCPIDLIYK 343 K EW+L++RHE+ED+FG Q+ + P AQ L+ + DF+D+N GCP++ I K Sbjct: 275 LQKSEWSLLRRHESEDIFGIQLAVSRPQEAATFAQALEASGFSYDFLDINCGCPVEKIVK 334 Query: 344 KGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLIT 403 G G G+ R L V + S P +K R G+ +D H + + S WGA+ +T Sbjct: 335 SGCGCGLWQRTERLRDVVESLAIYQSRPVAIKCRIGLDEDIPTLHQQIHRYSAWGAAAVT 394 Query: 404 VHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGR 463 VHGRSR+ RYTK ++W+Y++ CAQ T PV GNGDI S ED +E R+ P + MIGR Sbjct: 395 VHGRSRKQRYTKFANWDYVDQCAQL-TSLPVIGNGDIMSLEDVLEHRERQPHIASHMIGR 453 Query: 464 GALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSF 523 GALIKPW+F EIK ++ DISS +R ++LKK+ +G+ HWG+D +GV +TRRFL EWLSF Sbjct: 454 GALIKPWLFEEIKTGQVKDISSSERLDMLKKFCAHGMAHWGADERGVMTTRRFLCEWLSF 513 Query: 524 LYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFL 583 L+RYVPVGLLER PQRINERPP Y GRD+LETLM+S + DW++ISE+LLGPV F+F Sbjct: 514 LHRYVPVGLLERLPQRINERPPFYEGRDELETLMSSDSVKDWVRISELLLGPVERQFRFT 573 Query: 584 PKHKANSY 591 PKHK+NSY Sbjct: 574 PKHKSNSY 581 >UniRef50_A3LUK5 Cluster: Dihydrouridine synthase of tRNA; n=6; Saccharomycetales|Rep: Dihydrouridine synthase of tRNA - Pichia stipitis (Yeast) Length = 613 Score = 399 bits (982), Expect = e-109 Identities = 233/613 (38%), Positives = 357/613 (58%), Gaps = 56/613 (9%) Query: 7 GVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKNDSKTK 66 G+ AIK E+++QK I++ SFDD+ E + +E + K K Sbjct: 25 GMAAIKPEFIVQKDRIVD----------------SFDDDEAEGGERGVEEGKSGKGGKKK 68 Query: 67 KRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYN--NCKFIHDSKQFLNSKPKDI 124 +RGQNK+R + + +E + C ++LD ++ +K C Y C+ H+ +++L SKP DI Sbjct: 69 RRGQNKNRD-LKQKREEIRLCTSLLDPDN---IKTCAYGPEQCRSTHNVEEYLASKPVDI 124 Query: 125 GDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVN---REKFDQWKDDTK-NTLQPSLQT 180 C V++ G CP G+ CR+ H + ++ R + + + + + N + + Sbjct: 125 EGICPVFRAIGYCPAGLKCRWLQSHYDKETRKLIKDLGRTEASKIELNYEVNNVSHEARG 184 Query: 181 QLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGEDIKIGAVTDEDLIKLLPRERKT 240 +L+KK+Y+F +A K+++++D+ ++ D+N+ A+ E K T D + E+K Sbjct: 185 KLRKKQYDFAIAGKVIEYIDSTVQN-DENI---ANAKEQRKNNEATYVDAPYKIA-EKKR 239 Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE- 299 +D+ N +SPLTTVGNLP+RR+ K+ GAD+T EMAL LL+ EWAL K H TE Sbjct: 240 LDFRNAKIVSPLTTVGNLPYRRLMKKLGADITYSEMALSVPLLQATNAEWALPKAHRTEY 299 Query: 300 DLFGAQICGNNPYIITKVAQLLQENTE-LDFIDLNIGCPIDLIYKKGGGSGMMHRLPALE 358 +G QI + + KVA+++ TE + ++LN GCPIDL+Y++G GS ++ + PA Sbjct: 300 PGYGVQIATSKHWAAAKVAEIISRETEHVSELNLNCGCPIDLLYRQGQGSALLEQ-PARL 358 Query: 359 TSVRCASKLLS--IPFTVKMRTGVYQDKKITHTIVPK-MSNWGASLITVHGRSREARYTK 415 + A S IP TVK+RTG ++K T+V + ++ + IT+HGRSR+ RYTK Sbjct: 359 VRILKAMNASSGDIPVTVKIRTGSKENKNTAKTLVERLLAENDVAAITLHGRSRQQRYTK 418 Query: 416 SSDWEYIETCAQAA-----------------TPCPVYGNGDIFSYEDYVEMRKIAPTVKG 458 +DW YI Q C V GNGD+FS+ D+ + Sbjct: 419 EADWNYIAEVGQVVQQWNDKKEENKDSRDTQRTCFV-GNGDVFSHVDWYNAVN-TDGIDS 476 Query: 459 VMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLL 518 VM+ RGALIKPWIF E++ Q+ D ++ +R +ILK +S+Y LEHWG+D GV RRF+ Sbjct: 477 VMVARGALIKPWIFEEVEAQQYLDKTATERLDILKTFSDYALEHWGTDEYGVGLARRFMC 536 Query: 519 EWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPD 578 E+LSF +RY+P+G+LER P +INERPP + GR+++ETL+ S++ DWIKI+EM LG D Sbjct: 537 EFLSFTHRYIPLGILERLPPKINERPPQWKGRNEMETLLGSTDYKDWIKITEMFLGKSGD 596 Query: 579 GFQFLPKHKANSY 591 F F PKHK+NSY Sbjct: 597 DFVFTPKHKSNSY 609 >UniRef50_Q6C4K3 Cluster: Similar to DEHA0D12364g Debaryomyces hansenii; n=1; Yarrowia lipolytica|Rep: Similar to DEHA0D12364g Debaryomyces hansenii - Yarrowia lipolytica (Candida lipolytica) Length = 622 Score = 392 bits (966), Expect = e-107 Identities = 222/560 (39%), Positives = 320/560 (57%), Gaps = 37/560 (6%) Query: 59 DKNDSKTKKRGQNKSRPKIFKDGKES-KPCPTILDVESSEQLKICQYNN-CKFIHDSKQF 116 +K + K KK GQNK+R K K++ K C + L + + C Y + CKF HD +++ Sbjct: 68 EKPEEK-KKGGQNKNRS--LKQRKDAIKMCSSALQFKEDGSPQECSYGDKCKFEHDLQKY 124 Query: 117 LNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQWKDDTKNTLQP 176 L SKPKDI C V+ + G+CP+G CR+ S H ++G +V+ EK D+ + Sbjct: 125 LESKPKDIEGVCPVFDLTGQCPQGYKCRWLSSHRDSEGKLLVDEEKKKANADNKELNHVF 184 Query: 177 SLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGEDIKIGAVTDEDLIKLLPR 236 LQ+KKY+ +++ +K +D + + + T + E I+I D ++ P Sbjct: 185 KHLNPLQRKKYDLSKSDEAIKLIDAQIVRDEDDEQTKLEKKETIEI------DTGRIRPS 238 Query: 237 ERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRH 296 E+K +D K +SPLTTVGNLP+RR+ K+ GADVT GEMAL L++G K EWAL + H Sbjct: 239 EKKKLDLKGKYIVSPLTTVGNLPYRRLMKDLGADVTYGEMALTLPLIQGHKAEWALTRCH 298 Query: 297 ETE----DLFGAQICGNNPYIITKVAQLLQE-NTELDFIDLNIGCPIDLIYKKGGGSGMM 351 +E + FG Q+ + K AQ + E T + I+LN GCPIDL+Y++G GS +M Sbjct: 299 SSEVTEGNHFGVQVTAPKHWQAIKAAQAVSELCTGISEINLNCGCPIDLVYRQGAGSALM 358 Query: 352 HRLPALETSVRCASKLL-SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSRE 410 + VR S + +P TVKMRTG ++ + T+HGRSR Sbjct: 359 DQQGKTARIVRGMSMVSGDVPITVKMRTGTGSTPTAKKLTARLLAEGQTAAFTLHGRSRA 418 Query: 411 ARYTKSSDWEYIETCAQAAT-------------------PCPVYGNGDIFSYEDYVEMRK 451 RYTK +DW YI A + P V GNGD +++ D+ Sbjct: 419 QRYTKLADWNYIREVADSVVNTRDDVREKSELDDHVISHPTWVVGNGDCYTWSDWHRAVD 478 Query: 452 IAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVE 511 A V VM+ RGALIKPWIF E++ ++ D S+ +R E +K++ YGLEHWGSD GV Sbjct: 479 EA-HVDSVMVARGALIKPWIFEEVESRQHIDKSATERLEYFQKFAQYGLEHWGSDQYGVN 537 Query: 512 STRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEM 571 TRR+L E++SF +RYVP G+LE P ++N+RP + GRD++ETL+ SS+ DWIK++E Sbjct: 538 QTRRYLCEFMSFTHRYVPSGILEYLPAKMNDRPDLWKGRDEMETLLGSSDYRDWIKVTER 597 Query: 572 LLGPVPDGFQFLPKHKANSY 591 LGPV D F+F PKHK+N+Y Sbjct: 598 FLGPVGDEFEFTPKHKSNAY 617 >UniRef50_A4S3Q5 Cluster: Predicted protein; n=2; Eukaryota|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 361 Score = 386 bits (949), Expect = e-105 Identities = 174/360 (48%), Positives = 245/360 (68%), Gaps = 7/360 (1%) Query: 238 RKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHE 297 RK +D+ KLY++PLTTVGNLPFRR+C + GAD+T EMA+ +LLKG ++EWAL++RH Sbjct: 1 RKELDFKGKLYVAPLTTVGNLPFRRVCTDLGADITVSEMAMASNLLKGDRKEWALLRRHP 60 Query: 298 TEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPAL 357 +E +G Q+CG P ++ + A+L+ DFID+N+GCPID + KG GS +M L Sbjct: 61 SEKCYGIQVCGGYPDLMARCAELIDNEVSCDFIDVNMGCPIDGVCAKGAGSSLMRDTDRL 120 Query: 358 ETSVRCASKLLSIPFTVKMRTGVYQD--KKITHTIVPKMSNWGASLITVHGRSREARYTK 415 + VR + + S P T+K+R G + D K + H I+P+ WGA T+HGR+RE RY++ Sbjct: 121 KNVVRTMAAVSSTPVTIKLRMGYFDDPSKYVAHDIIPRAKAWGAFAATLHGRTREQRYSR 180 Query: 416 SSDWEYIETCAQAA--TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473 +DW YI CA A + + GNGD+++YEDY + V MIGRGA+IKPW+ Sbjct: 181 LADWSYIHRCADVAAKSEFTLIGNGDVYTYEDY-NAQVADNKVATCMIGRGAIIKPWLMT 239 Query: 474 EIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLL 533 EIKEQ+ WDIS+ +R ++ K + YGLEHWGSD+ GVE TRR+LLEW+S+ +RYVP+GLL Sbjct: 240 EIKEQRHWDISANERLDLFKDFCQYGLEHWGSDSMGVEKTRRYLLEWMSYTHRYVPIGLL 299 Query: 534 ER-PPQRINERPPTYFGRDDLETLMASSNCTDWIKISEML-LGPVPDGFQFLPKHKANSY 591 E+ +++ RP Y GR DLET +AS DW+++SE+ LG F+F+PKH +NSY Sbjct: 300 EQNVVPKLHLRPMRYVGRSDLETKLASDRLEDWLELSEICGLGKPDASFKFVPKHASNSY 359 >UniRef50_Q5CRK5 Cluster: Ylr401cp-like protein with 2 CCCH domains plus Dus1p tRNA dihydrouridine synthase Tim barrel; n=2; Cryptosporidium|Rep: Ylr401cp-like protein with 2 CCCH domains plus Dus1p tRNA dihydrouridine synthase Tim barrel - Cryptosporidium parvum Iowa II Length = 707 Score = 342 bits (840), Expect = 2e-92 Identities = 187/441 (42%), Positives = 260/441 (58%), Gaps = 51/441 (11%) Query: 199 LDTRNKSVDKNLNTSADVGEDIKIGAVTDEDLIKLLPRERKTID---WNNKLYLSPLTTV 255 LD + +N ++ ++ T++ LI + E++ + NKL L+PLTTV Sbjct: 267 LDEKGPKTITEINNQPNIEIQQELKLSTEDMLIGISIHEKEKCKHKIFRNKLILAPLTTV 326 Query: 256 GNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIIT 315 GNLPFRR+C +FGADVT EM LC +L G E AL+K+ E FG Q+ G N I Sbjct: 327 GNLPFRRLCLKFGADVTVSEMVLCNEILSGKASELALLKKSPEEKYFGIQLAGGNKSTII 386 Query: 316 KVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPF-TV 374 K + + E+ E DFID+N CP+ ++ KG GS ++ R+ LET V+ K++ TV Sbjct: 387 KTGEFINEHCEFDFIDINAACPLKSLHDKGAGSILVDRVSELETMVKGLKKVMDGKLVTV 446 Query: 375 KMRTG------------------------VYQDKKITHTIVPKMSNWGASLITVHGRSRE 410 K+R +Y + K TH I+ + + G +T+HGR+ Sbjct: 447 KVRMSHGGSPINKNLSEKDYFENFENWPVIYHNMK-THKILNILCDSGIDALTIHGRTSF 505 Query: 411 ARYTKSSDWEYIETCAQAATP------------------CP-VYGNGDIFSYEDYVEMRK 451 RYTK +DW YI+ C+ + CP + G GDI +++DY + + Sbjct: 506 QRYTKEADWSYIKYCSVLNSKLYSNKVVNNIQNSNHSLICPSIIGCGDIINFQDYQQHIQ 565 Query: 452 IAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVE 511 V VMIGRGAL+KPWIF EIKE + WDIS+ +RF+I+K+Y N GLEHWG+D +G+ Sbjct: 566 -NDLVDSVMIGRGALLKPWIFTEIKENRNWDISASERFDIIKQYVNLGLEHWGTDKRGIA 624 Query: 512 STRRFLLEWLSFLYRYVPVGLLERP--PQRINERPPTYFGRDDLETLMASSNCTDWIKIS 569 TRRFLLE+LSF +RY+P+G+LE+P Q N R P Y GR+DLET++ASSN +DWIKIS Sbjct: 625 LTRRFLLEFLSFFHRYIPIGILEQPIHTQNFNWRTPKYIGRNDLETMLASSNSSDWIKIS 684 Query: 570 EMLLGPVPDGFQFLPKHKANS 590 EM+LG VP F F+PKHKANS Sbjct: 685 EMILGKVPSDFVFIPKHKANS 705 >UniRef50_UPI0000499494 Cluster: conserved hypothetical protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved hypothetical protein - Entamoeba histolytica HM-1:IMSS Length = 515 Score = 332 bits (815), Expect = 2e-89 Identities = 161/357 (45%), Positives = 228/357 (63%), Gaps = 12/357 (3%) Query: 237 ERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRH 296 E+K +D KL L L T GNLPFR++ K FG DVT EM + ESL++G EWALVKR Sbjct: 162 EKKILDLKGKLILPSLCTFGNLPFRKVVKRFGCDVTMTEMIMAESLVEGKTSEWALVKRD 221 Query: 297 ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPA 356 +ED+FG Q+C N + K Q+L + + DF +LN CPID +YKKG G+ ++ R Sbjct: 222 SSEDIFGIQLCVGNSMLAAKACQVLN-SVDCDFYELNCACPIDYVYKKGMGAQLIERPKR 280 Query: 357 LETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS 416 +E+ + + P +K+RTG I ++P +++GA+++++HGR+R+ RYTKS Sbjct: 281 IESLLHAMRSVTERPVAIKVRTGK-SSNTIQDVLLPNCADYGAAMVSIHGRTRDQRYTKS 339 Query: 417 SDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 +DW++I+ A T CPV G GDI+ Y+DY + + V V IGRGALIKPWI+ EIK Sbjct: 340 ADWDFIKQ-ATTITQCPVIGVGDIYGYKDY--QKALDCGVATVAIGRGALIKPWIYTEIK 396 Query: 477 EQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERP 536 E++ WDISS +R +IL++Y+ GL HWGSD QG+ TR F+ L+F+ RYVPV + Sbjct: 397 EKRDWDISSSERLDILRQYALDGLSHWGSDAQGISKTREFMCHHLTFMTRYVPVHCVIET 456 Query: 537 PQRI-----NERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKA 588 Q I N+R Y RDD+E L+ S D+IKI+EM LGP P F ++PKH++ Sbjct: 457 NQEISIKVRNDRVMCY--RDDMEKLLTSDRLEDYIKITEMFLGPAPKDFVYVPKHQS 511 Score = 60.9 bits (141), Expect = 9e-08 Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 7/117 (5%) Query: 102 CQYNNCKFIHDSKQFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDHITADGFNIVNRE 161 C+ NCK+ HD K++L+ + + C ++K G CP G C + HI G I N E Sbjct: 64 CERENCKYSHDLKEYLSKRTDLLEGICPLFKEYGFCPNGYTCEWYKSHINEQGELITNNE 123 Query: 162 --KFDQWKDDTKNTLQPSLQTQLQKKKYNFDLAEKL----VKHLDTRNKSVDKNLNT 212 K +K+ NT +P L+ K++F + E+ K LD + K + +L T Sbjct: 124 LMKLHPFKEPL-NTQKPETLHVLRTNKFDFKIPEEFPVPEKKILDLKGKLILPSLCT 179 >UniRef50_Q9UTH9 Cluster: tRNA dihydrouridine synthase Dus3; n=1; Schizosaccharomyces pombe|Rep: tRNA dihydrouridine synthase Dus3 - Schizosaccharomyces pombe (Fission yeast) Length = 617 Score = 324 bits (796), Expect = 4e-87 Identities = 173/427 (40%), Positives = 254/427 (59%), Gaps = 32/427 (7%) Query: 194 KLVKHLDTRNKSVDKNLNTSADVG-EDIKIGAVTDEDLIKLLPRERKTIDWNNKLYLSPL 252 K + + V KN S +V ++I A ++ L L P+E+ IDW ++ L+PL Sbjct: 187 KETESVSLEETGVLKNQTVSVNVDLKEISSQARSNIALPTLRPQEKNLIDWRDRKILAPL 246 Query: 253 TTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVK--RHETE-------DLFG 303 TTVGN PFRR+C GAD EMA+C L++G + EWALV+ +E E + G Sbjct: 247 TTVGNPPFRRLCGSLGADTFYSEMAMCYPLMQGHQPEWALVRGLNYEREMMRGGRRGILG 306 Query: 304 AQICGNNPYIITKVAQLLQENTE-LDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 Q+ + TK AQ++ E + +DF+DLN GCPIDL++++G GS ++ L +++ Sbjct: 307 VQLATGKLWQATKTAQVIAEQCDGVDFLDLNCGCPIDLVFRQGAGSSLLENPGRLLRNLQ 366 Query: 363 CASKLLS-IPFTVKMRTGVYQDKKITHTIVPKMSN-WGASLITVHGRSREARYTKSSDWE 420 + IP TVK+R G D + ++ ++ N S T+HGRSR+ RY+K+++W+ Sbjct: 367 GMDAVSGQIPVTVKLRMGNKDDHPVVKNLIGRIFNETNTSAATLHGRSRQQRYSKNANWD 426 Query: 421 YIETCAQAAT-----------------PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGR 463 YI A P + GNGD +S++D+ + + V VMI R Sbjct: 427 YIGEIASKVKSMNERIDELPEDSLRTQPLSLIGNGDCYSWQDWYD--GVNKGVDTVMIAR 484 Query: 464 GALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSF 523 GAL+KPWIF EI+ ++ D SS R E+L++Y N GLE+WGSD+QGV +TRRF LE++SF Sbjct: 485 GALVKPWIFEEIEARQFIDKSSTQRLEMLEQYCNNGLEYWGSDSQGVNTTRRFFLEFMSF 544 Query: 524 LYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIKISEMLLGPVPDGFQFL 583 +RY P+ L E R+N+RPP Y RD++ETL+AS+ TDW+K+SE LGP P+ F F Sbjct: 545 FHRYTPIALYEVQRPRLNDRPPLYTARDEMETLLASNKVTDWVKLSEFFLGPTPERFTFT 604 Query: 584 PKHKANS 590 PKHK+NS Sbjct: 605 PKHKSNS 611 Score = 77.8 bits (183), Expect = 8e-13 Identities = 50/145 (34%), Positives = 78/145 (53%), Gaps = 11/145 (7%) Query: 56 ITEDKNDS-KTKKRGQNKSRPKIFKDGKESKPCPTILDVESSEQLKICQYN-NCKFIHDS 113 + +D N K K+RGQNK R KI + + CP I + + C Y NCKF HD Sbjct: 17 VKQDGNKKRKRKERGQNKRREKIHVK-ENNALCPAI-SIGNE-----CPYKENCKFPHDV 69 Query: 114 KQFLNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDH--ITADGFNIVNREKFDQWKDDTK 171 + +L +K DIGD+C +++ G CP G CR+ + H I ADG + ++ Q+ T Sbjct: 70 EAYLATKAPDIGDKCPIFERYGVCPAGFKCRWLAGHVVINADGKYELIKKPDGQFTLFTV 129 Query: 172 NTLQPSLQTQLQKKKYNFDLAEKLV 196 NT+ +Q +L+ K+ + AE ++ Sbjct: 130 NTVGKEVQRKLRTKQLDLSKAESII 154 >UniRef50_Q2UL89 Cluster: Uncharacterized conserved protein; n=15; Pezizomycotina|Rep: Uncharacterized conserved protein - Aspergillus oryzae Length = 730 Score = 308 bits (755), Expect = 4e-82 Identities = 226/624 (36%), Positives = 318/624 (50%), Gaps = 102/624 (16%) Query: 64 KTKKRGQNKSRPKIFKDGKESKP-CPT-ILDVESSEQLKICQYNN-CKFIHDSKQFLNS- 119 K K GQN +R F ++ K CP+ I E S CQ+ C+F HD + +L Sbjct: 107 KKKPTGQNTNRT--FGSSQDEKGLCPSRIFTPEFSPGA--CQWGEKCRFEHDLRTYLKEY 162 Query: 120 KPKDI---GDQCHVYKVRGKCPRGIACRYGSDHIT----ADGFNIV------NREKFDQ- 165 K D+ C V+ +GKC G CR H+T ADG + R+K Q Sbjct: 163 KRGDLTTFDGVCPVWDAKGKCLSGWKCRLVGSHMTERETADGRKELVLVEDEERKKKAQP 222 Query: 166 -----WKDDTKNTLQPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGEDI 220 +D T N + L +KK A+ LD ++ ++K ++ + +V E+ Sbjct: 223 LVPFAVEDGTANIAPIEAKIALNRKKVKTPRADAYGSWLDKTSRELEKVIH-NREVHEER 281 Query: 221 KIGAVTDEDLIK------------LLPRERKTIDWNNKL-YLSPLTTVGNLPFRRICKEF 267 + TD+ + LP E++ I + + L+PLTT GNLPFRR+C E Sbjct: 282 GAESKTDQAEREKEDNRAQYLEPPFLPSEKRRIYFGPETPVLAPLTTQGNLPFRRLCIEL 341 Query: 268 GADVTCGEMALCESLLKGLKQEWALVKRHETEDL---------------------FGAQI 306 GA T EMAL L++G + EWAL++ HETE L FGAQI Sbjct: 342 GAQFTYSEMALSMPLIQGQRGEWALMRAHETEMLPPTISPGADVVQGYDHSKDFRFGAQI 401 Query: 307 CGNNPYIITKVAQLLQENT-ELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 N + K ++L T L IDLN GCPIDL++++G GS ++ LE +R + Sbjct: 402 AANKHWQALKATEVLSAYTPNLRVIDLNCGCPIDLLFREGAGSALLEHPSKLERILRGMN 461 Query: 366 KLLS-IPFTVKMRTGVYQDK----KITHTIVPK--------MSNWGASLITVHGRSREAR 412 + IP T K+R G + K+ ++ + G + +T+HGRSR+ R Sbjct: 462 AVSQEIPITAKIRMGTRDNSPNALKLAERLILGGYESSTLGLGAPGVAALTLHGRSRQQR 521 Query: 413 YTKSSDWEYIETCAQ---------------AATPCP----------VYGNGDIFSYEDYV 447 YT+ +DW YI CA P P GNGD +S+ DY Sbjct: 522 YTRQADWGYISECAALIKRLNEKTDQVTDTVREPDPRTQPNGGKTWFLGNGDCYSHLDYD 581 Query: 448 EMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDT 507 + A V VM+GRGALIKPW+F EI+ + D S+ +R +++K++ YGLE WGSD Sbjct: 582 DHVNNAG-VDTVMVGRGALIKPWLFEEIQAGQYLDKSASERLSLVEKFAKYGLETWGSDE 640 Query: 508 QGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTDWIK 567 GV +TRRFLLEWLSF RY+P+GLLE P RI +RPP++ GR++LETLM S N DWIK Sbjct: 641 HGVGTTRRFLLEWLSFACRYIPIGLLEYLPPRIQDRPPSWRGRNELETLMGSHNYKDWIK 700 Query: 568 ISEMLLGPVPDGFQFLPKHKANSY 591 I+EM LGP F+F PKHK+N++ Sbjct: 701 ITEMFLGPAHKDFRFEPKHKSNAW 724 >UniRef50_Q06053 Cluster: tRNA-dihydrouridine synthase 3; n=6; Saccharomycetales|Rep: tRNA-dihydrouridine synthase 3 - Saccharomyces cerevisiae (Baker's yeast) Length = 609 Score = 245 bits (600), Expect = 2e-63 Identities = 139/398 (34%), Positives = 221/398 (55%), Gaps = 40/398 (10%) Query: 161 EKFDQWKDDTKNTLQPS--LQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADVGE 218 E D ++ + +++++P +++ Q KK + D+ + + ++ RNK + ++ +V Sbjct: 215 EIIDSFQQECRDSMKPEEEVESTPQLKKQDPDVEQPVAPQVEQRNKELSEHRMKQREVYL 274 Query: 219 DIKIGAVTDEDLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMAL 278 K + +E+K +D +K +SPLTTVGNLP+RR+ ++ GADVT EMAL Sbjct: 275 KYKD--------TRYFAQEKKPLDLYHKKIVSPLTTVGNLPYRRLMRKLGADVTYSEMAL 326 Query: 279 CESLLKGLKQEWALVKRHETE-DLFGAQICGNNPYIITKVAQLLQEN-TELDFIDLNIGC 336 L++G EWAL K H +E FG Q+ + + K A+ L + +E+ I+LN GC Sbjct: 327 AVPLIQGTNSEWALPKAHTSEFPGFGVQVACSKAWQAAKAAEALANSVSEISEINLNSGC 386 Query: 337 PIDLIYKKGGGSGMMHRLPALETSVRCASKL----LSIPFTVKMRTGVYQDKKITHTIVP 392 PIDL+Y++G GS ++ PA +RC + + IP TVK+RTG + I +V Sbjct: 387 PIDLLYRQGSGSALLDN-PA--RMIRCLNAMNYVSKDIPITVKIRTGTKEGHPIAEGLVK 443 Query: 393 KMSN-WGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPV----------------- 434 ++ N + IT+HGRSR+ RYTKS+DW+Y+ A Sbjct: 444 RLVNETDVAAITLHGRSRQQRYTKSADWDYVSQVADTLRSAEADFIETEQGKEGRDSKNR 503 Query: 435 ---YGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEI 491 GNGD+ ++ED+ + VM+ RGALIKPWIF E++ Q+ D +S +R +I Sbjct: 504 IQFVGNGDVNNFEDWYRYLNGNENIDSVMVARGALIKPWIFEEVESQQYLDKTSTERLDI 563 Query: 492 LKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVP 529 L+ Y+ + +EHWG+D G+ RRF E++SF +RYVP Sbjct: 564 LRDYAQFSMEHWGTDEYGISQCRRFFCEFMSFFHRYVP 601 Score = 66.1 bits (154), Expect = 2e-09 Identities = 55/223 (24%), Positives = 103/223 (46%), Gaps = 29/223 (13%) Query: 7 GVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKN-DSKT 65 G+ IK EY I+ K +K + + S D EF T KN + + Sbjct: 28 GIAHIKPEY------IVPLKQNENQKVAIYDEEMSSDRMTNEFAGG----TNKKNKNGRG 77 Query: 66 KKRGQNKSRPKIFKDGKESKP-CPTILDVESSEQLKICQY-NNCKFIHDSKQFLNSKPKD 123 KKRGQNK+R + KE CP ++ + S+ C + +NC+F+HD +L++K + Sbjct: 78 KKRGQNKNRDN--RQVKEQNVLCPRLIHGDISK----CSFGDNCRFVHDINLYLSTKKPE 131 Query: 124 IGDQ----CHVYKVRGKCPRGIACRYGSDHITADGFNIVNREKFDQ-----WK-DDTKNT 173 + C V+ G CP G CR+ S H+ + ++++++ D W N Sbjct: 132 VESNIFPSCPVFNSLGFCPMGFKCRFLSSHLNKEDNILISKKEIDPDAQTIWSVKGEVNH 191 Query: 174 LQPSLQTQLQKKKYNFDLAEKLVKHLDTRNKSVDKNLNTSADV 216 + P + L K+++ F + ++++ +D+ + ++ +V Sbjct: 192 ISPERKLDLIKRRFPFTKSNEILEIIDSFQQECRDSMKPEEEV 234 >UniRef50_Q2HDP2 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 641 Score = 244 bits (596), Expect = 7e-63 Identities = 140/328 (42%), Positives = 187/328 (57%), Gaps = 39/328 (11%) Query: 302 FGAQICGNNPYIITKVAQLLQENT-ELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS 360 FGAQI N P++ K + L + L +DLN GCP+D ++K G GS ++ LE Sbjct: 309 FGAQIAANAPWVAVKATEALSQLLPHLRLVDLNCGCPVDAVFKSGSGSALLDSHSKLERM 368 Query: 361 VRCASKLLS-IPFTVKMRTGVYQDKKITHTIVPKMSNW-----------GASLITVHGRS 408 +R + + +P T K+R G K +V +++ G + +T+HGR+ Sbjct: 369 IRGMNAVSGEVPITAKIRMGSRDGKLTAQKLVERLALGSEDLRDMIGAPGCAAVTLHGRT 428 Query: 409 REARYT--------------------KSSDW-EYIETCAQAATPC--PVY--GNGDIFSY 443 R RYT KS+D + I + P +Y GNGD +S+ Sbjct: 429 RLQRYTKAADWGYIAECAALIKQFNEKSNDLADTIREADENTLPNGGKMYFLGNGDCYSH 488 Query: 444 EDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHW 503 +Y + A V VMIGRGAL+KPW+F EI++ + D SS +R ++K+ YG+E W Sbjct: 489 VEYFDHVDNAK-VDSVMIGRGALVKPWVFEEIEKGQYLDKSSSERLTYIEKFVRYGMEAW 547 Query: 504 GSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCT 563 GSD G+ TRRFLLE+LSF RYVP+GLLER P +NERPP Y GRDDLETL AS N Sbjct: 548 GSDELGLNYTRRFLLEFLSFFCRYVPIGLLERLPPNLNERPPAYRGRDDLETLFASKNYK 607 Query: 564 DWIKISEMLLGPVPDGFQFLPKHKANSY 591 DWIKISEM LGP P GF+F PKHK+NSY Sbjct: 608 DWIKISEMFLGPAPPGFKFQPKHKSNSY 635 Score = 45.2 bits (102), Expect = 0.005 Identities = 45/156 (28%), Positives = 67/156 (42%), Gaps = 23/156 (14%) Query: 7 GVCAIKDEYVLQKSNIIEEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKN----- 61 GV IK EY+L +K K +S A DDN+ + + + T + Sbjct: 48 GVAPIKAEYLLFPPG---------QKAKPTQSEAEADDNDDDAAEGRTAPTPQETQQAPQ 98 Query: 62 -DSKTK-KRGQNKSRP-KIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFLN 118 D K K +RGQNK R F D + + C TI + C +HD +++L Sbjct: 99 KDGKRKSQRGQNKEREFGTFSDAQ--RLCNTIAWTPEFSPRPCKHGDRCNALHDLRKYLK 156 Query: 119 S-KPKDI---GDQCHVYKVRGKCPRGIACRYGSDHI 150 + DI G +C V++ GKCP G C + H+ Sbjct: 157 EGRRPDITTFGGKCPVWEKYGKCPSGWRCLFVHSHM 192 >UniRef50_Q7X346 Cluster: Putative uncharacterized protein; n=1; uncultured Acidobacteria bacterium|Rep: Putative uncharacterized protein - uncultured Acidobacteria bacterium Length = 355 Score = 200 bits (488), Expect = 8e-50 Identities = 119/326 (36%), Positives = 168/326 (51%), Gaps = 6/326 (1%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308 ++P+T NLP+RR+C E GA +T EM L L + E+AL++R E FG Q+ G Sbjct: 1 MAPMTKGSNLPYRRLCVELGARITVSEMTLARRLKQKRNSEFALIRRFPGEPCFGVQLAG 60 Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC-ASKL 367 N P T A L E+ DF+D+N GCPID +KG G+ + + + V + Sbjct: 61 NKP-DETAWAAALVESRGADFVDINFGCPIDYFTRKGLGASIGRQPQRMRRLVEAIKGSV 119 Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427 +IP T K+R G D + + GA+ + VHGR+R ARY ++DW+ I Sbjct: 120 TNIPVTAKIRLGWNDDDRNYLQQAQAAVDGGAAALFVHGRTRNARYRFAADWDAIARIV- 178 Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKD 487 AA P PV GNGD+ + R+ + VM+ R ALIKPWIF E + WDI++++ Sbjct: 179 AAVPVPVIGNGDLLFPHEIAAARERSGCA-AVMVARAALIKPWIFREAVD-GYWDITAEE 236 Query: 488 RFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTY 547 R + ++Y EHWG D G+ R FL L F YRYVP L + + R T Sbjct: 237 RVGLYRRYVTLAREHWGDDEHGLARIRTFLNWHLEFWYRYVP-RLEDGTFASMQRRVDTV 295 Query: 548 FGRDDLETLMASSNCTDWIKISEMLL 573 R LE L+A + I+E LL Sbjct: 296 PARSPLEALLARGDAAAKEYIAECLL 321 >UniRef50_A4S604 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 287 Score = 197 bits (480), Expect = 8e-49 Identities = 111/288 (38%), Positives = 157/288 (54%), Gaps = 6/288 (2%) Query: 246 KLYLSPLTTVGNLPFRRIC-KEFGADVTCGEMALCESLLKGLKQEWALVKRHETE--DLF 302 +L+L+PLT GN PFRR+C EFGA+V EMA L KG + E A V+RHE + D F Sbjct: 3 QLWLAPLTKGGNAPFRRLCASEFGAEVVVSEMAFARFLAKGARVERARVRRHEGDAGDCF 62 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 GAQI N A + DF+DLN GCPI +K+G G+ ++ + LE V Sbjct: 63 GAQIATNAIEEGVNAALIASGEFGADFVDLNCGCPIHETWKRGLGAALLKKPAKLERLVE 122 Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 + + +P TVK+R G+ + I + N GAS + VHGR++E RYTK++D++ I Sbjct: 123 GIASRIDVPLTVKIRLGIDSSSQ-ARRIAEGLENAGASAVVVHGRTKEQRYTKAADYDVI 181 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWD 482 + P+ GNGD+ ++ D + R V +M+GRGALIKPWIF E +E+K W+ Sbjct: 182 RDIVRERN-IPIIGNGDVLTWYDARD-RMEHSGVAAMMVGRGALIKPWIFKEYRERKCWN 239 Query: 483 ISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPV 530 + + R + NY E +G D G F L F RY P+ Sbjct: 240 PTVEQRVGVYYTLRNYMREGFGDDELGKRRFDEFFPWHLGFFCRYRPL 287 >UniRef50_Q7R3K2 Cluster: GLP_158_4738_3071; n=1; Giardia lamblia ATCC 50803|Rep: GLP_158_4738_3071 - Giardia lamblia ATCC 50803 Length = 555 Score = 183 bits (445), Expect = 1e-44 Identities = 88/162 (54%), Positives = 116/162 (71%), Gaps = 3/162 (1%) Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRF 489 TP + GNGDIF Y D R TV +I RGAL+KPWIF EIKE + D+SS+ R Sbjct: 391 TPPLLGGNGDIFDYTDL--HRDDHSTVDYYLIARGALVKPWIFQEIKEGRRIDMSSQSRL 448 Query: 490 EILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFG 549 E+LK ++++ LE++GSD GVE R LE SF+ RY+PVG+L+ PQ++N+RPP + G Sbjct: 449 EMLKLFASFCLEYYGSDAPGVEKARAQFLENWSFMCRYIPVGILDE-PQKLNQRPPMFRG 507 Query: 550 RDDLETLMASSNCTDWIKISEMLLGPVPDGFQFLPKHKANSY 591 RD+LETLMAS + +DW+ ISEML GPVP GF F+PKHK++ Y Sbjct: 508 RDELETLMASQSASDWVTISEMLFGPVPAGFSFVPKHKSHGY 549 Score = 112 bits (270), Expect = 2e-23 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 L L+P+ TVG +PFRR+C +G ++T EM +L G QE +KRH E FG Q+ Sbjct: 176 LMLAPMCTVGTIPFRRLCIHYGCEITLCEMVFARDILHGDAQELRKIKRHPDEKCFGIQL 235 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC--- 363 G ++ ++ + + DFIDLN CP D+ KK G+ + L L +SV C Sbjct: 236 AGRGQELM-EIVNFISQCCSCDFIDLNAACPQDIATKKCCGAALAANLKKLVSSVDCMVR 294 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 + +P +K+R G + ++ + G ++VH R+ + RY+K ++W+Y+ Sbjct: 295 GGEHYGVPVFLKIRAGDLRGDWTGDSVAQALRLSGLYGLSVHLRTAKQRYSKLANWDYLV 354 Query: 424 TCAQAATPC 432 + A C Sbjct: 355 SMRHALDNC 363 Score = 40.3 bits (90), Expect = 0.14 Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 100 KICQYNNCKFIHDSKQF-LNSKPKDIGDQCHVYKVRGKCPRGIACRYGSDH 149 K C+ C HD +F + P CH K GKCP + C Y S H Sbjct: 54 KQCKNPKCNAYHDLDEFSVYYTPPQTSISCHFLKTYGKCPFSVNCMYASSH 104 >UniRef50_A4XH30 Cluster: Putative TIM-barrel protein, nifR3 family; n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep: Putative TIM-barrel protein, nifR3 family - Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) Length = 328 Score = 157 bits (381), Expect = 8e-37 Identities = 82/232 (35%), Positives = 126/232 (54%), Gaps = 2/232 (0%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305 KL+L+P+ + FR +C FGADVT EM +++ G ++ L+ E E + G Q Sbjct: 7 KLFLAPMAGFTDKVFRSLCSRFGADVTVTEMVSAKAITMGSQKTKELISFSEDEKIKGVQ 66 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 I G++P+++ + +++Q+ E DFID+N+GCP+ + K G GS +M V + Sbjct: 67 IFGSDPHVMAEAVKIIQDEFEYDFIDINMGCPVPKVVKSGEGSALMKNPSLAAKIVEEVA 126 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425 K+ P +VK+R G ++ M GAS ITVHGR+R Y+ +DWE I+ Sbjct: 127 KVSRKPVSVKIRKGFDEENINAPEFACIMQESGASFITVHGRTRTQMYSGKADWEIIK-M 185 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 + PV NGDI +E + +I +MIGR AL PW+F +IKE Sbjct: 186 VKEKVKIPVVANGDIVDFESAKKAYEIT-EADSIMIGRAALGNPWVFLQIKE 236 >UniRef50_Q899H0 Cluster: Nitrogen regulation protein nifR3; n=24; Clostridia|Rep: Nitrogen regulation protein nifR3 - Clostridium tetani Length = 322 Score = 144 bits (348), Expect = 8e-33 Identities = 88/282 (31%), Positives = 137/282 (48%), Gaps = 8/282 (2%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETED 300 ++ ++L+PL V +L FR +CK G + EM ++L + +++ + E Sbjct: 6 LELKGNVFLAPLAGVTDLAFRGLCKRMGCTLVYTEMVSAKALFYDSDKTKDMLRFSKEEL 65 Query: 301 LFGAQICGNNPYIITKVAQ-LLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359 QI G P I+ V + N + ID+N+GCP I K G GS +M Sbjct: 66 PIAVQIFGKEPDIMANVVEKYFNSNDNVCLIDINMGCPAPKIVKNGEGSALMKNPKLASD 125 Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419 V K+ + P TVK R G D M N GA +T+HGR+RE Y +DW Sbjct: 126 IVESIKKVSTKPVTVKFRKGFDNDNINALEFAKIMENSGADALTIHGRTREQMYQGKADW 185 Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE-- 477 E I+ + + PV GNGD+F+ ED + M + + GVM+ RGAL PWIFN+I E Sbjct: 186 EIIKK-VKESVKIPVIGNGDVFTGEDAINMIE-STNCDGVMVARGALGNPWIFNQISEAL 243 Query: 478 --QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFL 517 Q+I + S + E+ ++ L ++ + + V R+ + Sbjct: 244 KGQQILEPSPDEILEVCIEHFKRALYYY-DEKKAVREMRKHI 284 >UniRef50_A5BP75 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 940 Score = 140 bits (339), Expect = 1e-31 Identities = 61/87 (70%), Positives = 73/87 (83%) Query: 505 SDTQGVESTRRFLLEWLSFLYRYVPVGLLERPPQRINERPPTYFGRDDLETLMASSNCTD 564 +D GVE+TR F+LEWLS+ YRYVPVGLL+ PQ++N RPP+YFGRDDLETLMAS + D Sbjct: 570 ADDGGVETTRHFMLEWLSYTYRYVPVGLLDVIPQQLNWRPPSYFGRDDLETLMASDSAAD 629 Query: 565 WIKISEMLLGPVPDGFQFLPKHKANSY 591 WI+ISEMLLG VP GF F PKHK+N+Y Sbjct: 630 WIRISEMLLGKVPPGFSFAPKHKSNAY 656 >UniRef50_A6LGT0 Cluster: Putative TIM-barrel enzyme; n=1; Parabacteroides distasonis ATCC 8503|Rep: Putative TIM-barrel enzyme - Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152) Length = 329 Score = 138 bits (333), Expect = 5e-31 Identities = 81/277 (29%), Positives = 141/277 (50%), Gaps = 9/277 (3%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 ++L+P+ V ++ FR +CK FGAD+ E ++L++ + + + + E QI Sbjct: 13 VFLAPMEDVTDISFRLMCKRFGADMVYTEFVSSDALIRSVNKTQQKLNVSDDERPVAIQI 72 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 G + + + A++ +E D +D+N GCP+ + KG G+GM+ +P + R K Sbjct: 73 YGKDVASMVEAARICEE-ARPDILDINFGCPVKKVAGKGAGAGMLRNIPLMLEITREVVK 131 Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426 ++IP TVK R G D ++ + ++ + G + +++HGR+R YT +DW I Sbjct: 132 AVNIPVTVKTRLGWDADNRVIVDLAEQLQDCGIAALSIHGRTRAQMYTGEADWTLIRAVK 191 Query: 427 -QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ-KIWDIS 484 P+ GNGD+ S E + R V VMIGR ++ +PWIF E+K ++ Sbjct: 192 NNPRMQIPIIGNGDVTSAE-ICKQRFEDYGVDAVMIGRASIGRPWIFREVKHYLTTGELL 250 Query: 485 SKDRF----EILKKYSNYGLEHWGSDTQGVESTRRFL 517 ++ F +ILKK +E + +G+ RR L Sbjct: 251 PQEPFSWYLDILKKQVEQSVERL-DERRGILHIRRHL 286 >UniRef50_Q7MXX6 Cluster: TIM-barrel protein, putative, NifR3 family; n=23; Bacteroidetes/Chlorobi group|Rep: TIM-barrel protein, putative, NifR3 family - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 333 Score = 136 bits (330), Expect = 1e-30 Identities = 74/231 (32%), Positives = 124/231 (53%), Gaps = 3/231 (1%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 L L+P+ V ++ FR +CK+FGAD+ E ++L++ + + + E+E QI Sbjct: 13 LLLAPMEDVTDVAFRIMCKQFGADLVYSEFLSADALIRQVAGTFRKMAIDESERPMAVQI 72 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 G + + + A+L E+ + IDLN GCP+ + KG GSGM+ +P + R K Sbjct: 73 YGRDVASMVEAARLC-ESAGPNLIDLNFGCPVKRVAGKGAGSGMLRNIPLMIEITREVVK 131 Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI-ETC 425 + +P TVK R G D KI + ++ + G + +T+HGR+R YT ++DW I E Sbjct: 132 AVKLPVTVKTRLGWDNDSKIIVDLAEQLQDCGIAALTIHGRTRAQMYTGTADWTLIGEVK 191 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 P+ GNGD+ + ++ + V VM+GR ++ +PWIF ++K Sbjct: 192 NNPRMQIPIIGNGDVTTPQEARRAFDVY-GVDAVMVGRASIGQPWIFEDMK 241 >UniRef50_Q1IVR5 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=2; Acidobacteria|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Acidobacteria bacterium (strain Ellin345) Length = 370 Score = 135 bits (327), Expect = 3e-30 Identities = 91/285 (31%), Positives = 149/285 (52%), Gaps = 22/285 (7%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGL-KQEWALVKRHET----EDLFG 303 L+P+ V + FRR + G CG M + GL + A +R+ T E Sbjct: 36 LAPMAGVTDTVFRRFIRNLGG---CGLMMTEFTSADGLARMREAKARRYLTFYGNERPIS 92 Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 AQ+ G++ + A+++Q+ D +DLN+GCP + K GGSG++ LP ++ Sbjct: 93 AQLFGSDAETLADAAKVVQD-LGFDLVDLNLGCPSKRVVKCNGGSGLLRDLPQIKVIFES 151 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITVHGRSREARYTKSSDWEYI 422 K ++IPFTVK R G + +K++ + K++ N G + + +H R+RE Y+ ++W +I Sbjct: 152 VRKAVTIPFTVKFRAG-WNEKELVFLELAKLAENCGLNAVAMHARTREQGYSGQANWGWI 210 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIFNEIKEQKI- 480 Q PV GNGDI + ED M +A T VMIGR A PWIF +I++ Sbjct: 211 ADLKQ-VVKIPVIGNGDIRTPEDAAAM--VAKTGCDAVMIGRSAASNPWIFRQIEQYTAT 267 Query: 481 --WDI-SSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLS 522 +D+ +++DR+E+++ Y +E +DTQG E + W + Sbjct: 268 GRYDLPTNEDRYEMIRMYFRMLIE---NDTQGAEGKMKQFASWFT 309 >UniRef50_Q0F181 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=1; Mariprofundus ferrooxydans PV-1|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Mariprofundus ferrooxydans PV-1 Length = 341 Score = 135 bits (327), Expect = 3e-30 Identities = 81/245 (33%), Positives = 125/245 (51%), Gaps = 4/245 (1%) Query: 232 KLLPRERK-TIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEW 290 +LLP R T +N L L+P+ + +LPFRRICK FG + EM ++ G ++ Sbjct: 4 RLLPGFRLGTYMIDNPLVLAPMAGITDLPFRRICKRFGVGLMVTEMIASRAVDMGRERTE 63 Query: 291 ALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGM 350 + + + E QI G++P +T+ A+ + DF+D+N+GCP+ I K+ GS M Sbjct: 64 RMAELGDDEHPVSIQIAGSDPEFVTEAARWAVGHGA-DFVDINMGCPVKKICKQVAGSAM 122 Query: 351 MHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSRE 410 + + + + +P T+K+RTG K I + G L+TVHGR+R Sbjct: 123 LRDEALVARVLAAVVAAVDVPVTLKIRTGWDDQSKNVQNIARIAEDSGIQLLTVHGRTRA 182 Query: 411 ARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPW 470 + + WE I A+AA PV GNGDI E EM +++ GVM+GR PW Sbjct: 183 QMFHGHACWEDI-GLAKAAVSIPVIGNGDIVDAESAREMIRVS-NCDGVMVGRAVQGNPW 240 Query: 471 IFNEI 475 + E+ Sbjct: 241 VLGEV 245 >UniRef50_Q64MI4 Cluster: Putative TIM-barrel enzyme; n=3; Bacteroidales|Rep: Putative TIM-barrel enzyme - Bacteroides fragilis Length = 324 Score = 133 bits (322), Expect = 1e-29 Identities = 71/231 (30%), Positives = 121/231 (52%), Gaps = 3/231 (1%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 ++L+P+ V + FR +CK+FGAD+ E ++L++ + + + + E QI Sbjct: 13 VFLAPMEDVTDPAFRLMCKKFGADMVYTEFVSSDALIRSVNKTTQKLTICDEERPVAIQI 72 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 G + + A++++E + D +D+N GCP+ + KG G+GM+ +P + R Sbjct: 73 YGKDTEAMVGAARIVEE-AQPDILDINFGCPVKKVAGKGAGAGMLQNIPKMLEITRAVVD 131 Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI-ETC 425 + IP TVK R G D KI + ++ + G + + +HGR+R YT +DW I E Sbjct: 132 AVKIPVTVKTRLGWDADHKIIVDLAEQLQDCGIAALAIHGRTRAQMYTGEADWTLIGEVK 191 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 P+ GNGD+ + E + V +MIGRG++ +PWIF E+K Sbjct: 192 NNPRMHIPIIGNGDVTTAAGAKECFE-RYGVDAIMIGRGSIGRPWIFREVK 241 >UniRef50_Q9RDC6 Cluster: Putative uncharacterized protein SCO2497; n=5; Bacteria|Rep: Putative uncharacterized protein SCO2497 - Streptomyces coelicolor Length = 406 Score = 132 bits (319), Expect = 3e-29 Identities = 74/231 (32%), Positives = 123/231 (53%), Gaps = 6/231 (2%) Query: 249 LSPLTTVGNLPFRRICKEF--GADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 L+P+ + N PFR +C+EF G + EM +L++ ++ L+ TE Q+ Sbjct: 29 LAPMAGITNAPFRTLCREFSGGKGLFVSEMITTRALVERNEKTMQLIHFDATETPRSIQL 88 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR-CAS 365 G +P + K +++ E D IDLN GCP+ + +KGGGS + ++ L VR + Sbjct: 89 YGVDPVTVGKAVRMIAEEGLADHIDLNFGCPVPKVTRKGGGSALPYKRHLLRAIVREAVT 148 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITVHGRSREARYTKSSDWEYIET 424 +P T+KMR G+ D +T+ +++ G + I +HGR+ Y ++DW+ I Sbjct: 149 GAGDLPVTMKMRKGL-DDDHLTYLDAGRIAVEEGVTAIALHGRTTAQHYGGTADWDAIAR 207 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 + PV GNGDI+S ED + M + GV++GRG L +PW+F ++ Sbjct: 208 LKEHVPEIPVLGNGDIWSAEDALRMVR-ETGCDGVVVGRGCLGRPWLFADL 257 >UniRef50_Q8GQD1 Cluster: NifR; n=5; Leptospira|Rep: NifR - Leptospira interrogans Length = 329 Score = 132 bits (319), Expect = 3e-29 Identities = 80/279 (28%), Positives = 146/279 (52%), Gaps = 7/279 (2%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305 K+ LSP+ + + P RRIC++FGA + E + L+ + + + E Q Sbjct: 12 KISLSPMAGISDSPTRRICRKFGAAFSYTEFVNTDELVHRAPKALKMFRYKLEERPITFQ 71 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 I GN II + A+++QE + D IDLN+GC + +G G+G++ R + Sbjct: 72 IFGNRLEIIAEAAEIIQE-LKPDIIDLNMGCSTRKVSLRGAGAGLLRRPLLAGKIIEAIK 130 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425 K ++IP T K+R G + + + G +TVHGR++E YT +DW+ I Sbjct: 131 KRVNIPVTAKIRIGWDSTSRNYLEVSKILEESGVDALTVHGRTKEMAYTGFADWDAIGE- 189 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISS 485 + P++GNGDI S+++ + + GV+IGR A+ PWIF+ +K++ ++S Sbjct: 190 IKVNRKIPIFGNGDIKSFQE-ANFKIDKYLLDGVLIGRNAIGNPWIFSGVKKE---ELSW 245 Query: 486 KDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFL 524 + ++ ++ + +E +G + G+ R+ L+++L+ L Sbjct: 246 SEVLAVILQHLRWMIEDYGEEF-GLVLFRKHLVKYLNGL 283 >UniRef50_Q6F288 Cluster: TRNA dihydrouridine synthetase; n=3; Mollicutes|Rep: TRNA dihydrouridine synthetase - Mesoplasma florum (Acholeplasma florum) Length = 325 Score = 132 bits (318), Expect = 3e-29 Identities = 81/237 (34%), Positives = 116/237 (48%), Gaps = 5/237 (2%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETED 300 ++ KL P+ V N PFR I KE GAD+ C EM E + K+ ++++ + E Sbjct: 6 VEIKGKLVQGPMAGVSNPPFRLISKEKGADLVCAEMVSVEGMTHNNKKTFSMLAVEKKEH 65 Query: 301 LFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLI-YKKGGGSGMMHRLPALET 359 QI GN+ + + EN + D IDLNIGCP + + GS ++ + Sbjct: 66 PMSMQIFGNDVESFIVATKWIDENVDCDIIDLNIGCPAPKVAVRSASGSSLLKTPELIYD 125 Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKM-SNWGASLITVHGRSREARYTKSSD 418 V+ + S P T K+R G + + + V K+ GAS ITVHGR+R Y+ +D Sbjct: 126 IVKAVVENTSKPVTAKIRLG-WDKESVNAVEVSKLIEKAGASGITVHGRTRSEFYSGHAD 184 Query: 419 WEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 WE I+ +A PV GNGD+ M ++ GVMI RG PWIF EI Sbjct: 185 WEKIKEVKEAVN-IPVIGNGDVIDGPSAKAMLELT-GCDGVMISRGCQGNPWIFREI 239 >UniRef50_A1IF01 Cluster: Dihydrouridine synthase family protein; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Dihydrouridine synthase family protein - Candidatus Desulfococcus oleovorans Hxd3 Length = 326 Score = 130 bits (314), Expect = 1e-28 Identities = 79/262 (30%), Positives = 124/262 (47%), Gaps = 7/262 (2%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308 L+PL + + PFRR+ K G + EM L ++ A+++ E F QI G Sbjct: 14 LAPLAGITDAPFRRLAKAAGCALVYSEMVSSHGLFYQSEKTGAMLRTTPEEAPFAVQIFG 73 Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL 368 P ++ + A ++Q + ID+N GC + I K G G+ +M LP ++ + Sbjct: 74 GKPAVMGRAAAMVQASGA-HMIDINFGCSVKKILKSGAGAALMKDLPLAAEVIQAVRDAV 132 Query: 369 SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQA 428 SIP T+KMR+G D + G + + +H R+ + ++DW I Q Sbjct: 133 SIPLTIKMRSGWNPDGSDAFHLAEIAEARGVNAVALHPRTATQGFGGTADWSLIAALKQ- 191 Query: 429 ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE----QKIWDIS 484 T PV GNGDI ED M VM+GR A+ PWIF +I + + + S Sbjct: 192 RTGLPVIGNGDIVLPEDARRMLD-QTGCDAVMVGRAAIGAPWIFKQINACLAGKPVVEPS 250 Query: 485 SKDRFEILKKYSNYGLEHWGSD 506 + RFE++ +Y N + H+G D Sbjct: 251 LEHRFEVMSEYINAMVAHYGED 272 >UniRef50_Q6AJZ5 Cluster: TRNA-dihydrouridine synthase; n=1; Desulfotalea psychrophila|Rep: TRNA-dihydrouridine synthase - Desulfotalea psychrophila Length = 328 Score = 129 bits (312), Expect = 2e-28 Identities = 79/231 (34%), Positives = 118/231 (51%), Gaps = 5/231 (2%) Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLF 302 +++ L+PL +L FR +C +FGAD T EM C L ++ ++ E Sbjct: 9 FSSPFVLAPLAGYTDLSFRLLCHQFGADYTVSEMISCHGLFYNQQRTLEMLASLPEERPV 68 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 Q+ G P I+ K A L+ + + D ID+N+GCP+ + KKG G+ +M +R Sbjct: 69 SFQLFGAEPDIMAK-ATLILNDFQPDMIDINMGCPVRKVTKKGAGAALMSTPELAYDVIR 127 Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 IP TVK R GV + GA+ + VHGR+R ++ +D I Sbjct: 128 SVVDNTDIPVTVKFRAGVSSTELNGVEFGLMTERAGAAAVAVHGRTRAQAFSGVADRGII 187 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIF 472 + +A + PV GNGDI SY+D ++M +A T GVM+GRGAL PW+F Sbjct: 188 KEVKEALS-IPVIGNGDILSYQDGLDM--MAETGCDGVMVGRGALGNPWVF 235 >UniRef50_Q1Q3Q8 Cluster: Strongly similar to tRNA-dihydrouridine synthase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to tRNA-dihydrouridine synthase - Candidatus Kuenenia stuttgartiensis Length = 341 Score = 129 bits (311), Expect = 2e-28 Identities = 79/259 (30%), Positives = 135/259 (52%), Gaps = 6/259 (2%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305 +L L+P+ ++P+R IC+ FG ++ E+ ++ K+ + L+ E E Q Sbjct: 34 ELILAPMAGFSDMPYRLICRRFGMSMSYTEVVSVSGIVWNNKKTFKLLDFKEEERPVTFQ 93 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 + GN+ IT+ + + E D ID+N+GC + I KG G+GM+ + + Sbjct: 94 VVGNDECQITEACKKI-EQLGPDIIDINMGCSVSDIAGKGAGAGMLKHPSKISKMFNNLT 152 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425 LS+P T K+R G + + + GASLI VHGR+R ++ ++DW+ I Sbjct: 153 GSLSVPVTGKIRLGWDHKTRNYIEVARILEENGASLIAVHGRTRSQYFSGAADWDAIAEV 212 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISS 485 Q + PV NGD+ S D E++K GVMIGR A+ PWIF K+++ +IS Sbjct: 213 KQ-SVKIPVIANGDVRSVADIAEIKK-RTACDGVMIGRAAIGHPWIF-RYKDRE--NISG 267 Query: 486 KDRFEILKKYSNYGLEHWG 504 ++ E+++ + + E++G Sbjct: 268 SEKIEMIRYHLDCMKEYYG 286 >UniRef50_Q8KB61 Cluster: TIM-barrel protein, nifR3 family; n=10; Chlorobiaceae|Rep: TIM-barrel protein, nifR3 family - Chlorobium tepidum Length = 352 Score = 128 bits (310), Expect = 3e-28 Identities = 92/305 (30%), Positives = 145/305 (47%), Gaps = 12/305 (3%) Query: 240 TIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE 299 TID + + L+P+ V + FR++CK+ GAD+ E E+L +G+++ + + E Sbjct: 10 TIDIDRPIILAPMEDVTDRAFRQLCKQHGADIVYTEFISAEALRRGVEKSIRKITVADHE 69 Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359 QI GN + + A + E E D++D+N GCP+ + +G G+ ++ L Sbjct: 70 RPVAVQIFGNTVESMVEAAAIA-ETYEPDYLDINFGCPVKKVAGRGAGAALLKEPEKLSE 128 Query: 360 SVRCASKLLSIPFTVKMRTGVYQDK-KITHTIVPKMSNWGASLITVHGRSREARYTKSSD 418 +S+P T K R G D IT T V ++ + G + VHGR+R Y +D Sbjct: 129 IASAVVNAVSLPVTAKTRIGWDHDSINITDT-VRRLEDAGIRAVAVHGRTRSDMYKGRAD 187 Query: 419 WEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE- 477 W I QA + PV NGD++ ED V M + G+MIGRG++ P+IF + K Sbjct: 188 WGRIAEAKQACS-IPVIANGDVWLPEDAVAMFE-RTGADGIMIGRGSIGNPFIFEQAKSL 245 Query: 478 ----QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVPV-GL 532 ++ S + R + + LE+ G + GV RR +L L V L Sbjct: 246 VKEGVRLSAPSYRQRIQAAVDHLRLSLEYKG-EKYGVLEMRRHYSTYLKGLPGVSKVRNL 304 Query: 533 LERPP 537 L R P Sbjct: 305 LVREP 309 >UniRef50_Q6MRF1 Cluster: Transcription regulator homolog yacF; n=1; Bdellovibrio bacteriovorus|Rep: Transcription regulator homolog yacF - Bdellovibrio bacteriovorus Length = 337 Score = 128 bits (310), Expect = 3e-28 Identities = 73/228 (32%), Positives = 113/228 (49%), Gaps = 3/228 (1%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N L+P+ + + FR K+ A V E+ + + L+ E++ G Sbjct: 10 NPFVLAPMAGITDHAFRTFIKKLDASVVVTELVSASGIEYKSDRTLKLMSFDESQRPIGI 69 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G P I+ + AQ+ + + DF+DLN GCP+ + KKG GS ++ A++ V Sbjct: 70 QLFGEEPEIVARAAQVAEADG-CDFVDLNFGCPVPKVVKKGAGSAILKDPAAVQKMVSTV 128 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 + IP T+K+RTG + + I N G S + +HGR+R YT +DW++I Sbjct: 129 KAAIKIPLTIKIRTGWDANSRNATEICNIAYNEGVSWVAIHGRTRAQSYTGLADWDFIAD 188 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 +A T P+ GNGDI + +R GVMIGRG L P+IF Sbjct: 189 -VKANTKIPILGNGDILTPRQ-ANLRLQQSGCDGVMIGRGCLKNPFIF 234 >UniRef50_Q0YFW9 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=8; Desulfuromonadales|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Geobacter sp. FRC-32 Length = 343 Score = 128 bits (310), Expect = 3e-28 Identities = 77/237 (32%), Positives = 128/237 (54%), Gaps = 8/237 (3%) Query: 240 TIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE 299 ++ N L L+P+ + NLP R + +E GA +T EM L++ K+ + L++R + Sbjct: 26 SLQLENNLILAPMAGLTNLPMRILARECGAALTFTEMISVNGLVREGKKTFDLLRRDPMD 85 Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359 G QI G++P ++ + A+L+++ EL ID+N+GCP+ + G GS ++ + Sbjct: 86 RPMGIQIFGDDPQLLAEGARLVEQYGEL--IDINMGCPVRKVVGSGAGSALLREPAKVGM 143 Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSN-WGASLITVHGRSREARYTKSSD 418 ++ K S+P T+K+RTG + T + +++ G +T+H RSR + +D Sbjct: 144 IIKAVRKATSLPLTIKIRTG-WGAADHTFLEIGRIAEAEGVDGVTLHPRSRAQMFEGHAD 202 Query: 419 WEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIFNE 474 W I +A + PV G+GDIF+ D V M I T GVM+ RG L PW+F E Sbjct: 203 WSRIRELKEALS-IPVIGSGDIFTAADVVAM--IDQTGCDGVMVARGGLGNPWLFRE 256 >UniRef50_Q1NXZ7 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3 precursor; n=2; delta proteobacterium MLMS-1|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 precursor - delta proteobacterium MLMS-1 Length = 313 Score = 128 bits (309), Expect = 4e-28 Identities = 81/235 (34%), Positives = 122/235 (51%), Gaps = 8/235 (3%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 L +PL +LPFR +C+E+GA + EM C L++ ++ E Q+ Sbjct: 15 LVAAPLAGYSDLPFRLLCREYGAGLCYSEMLSCHGLVRRQPATIEMLATTAAERPLLMQL 74 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 G P ++ + A +L +D ID+N+GCP+ + KKG G+ +M R P L ++ A Sbjct: 75 FGAEPEVMGEAAAIL-SRLPIDGIDINMGCPVRKVVKKGAGAALM-RDPELAAAITGAVT 132 Query: 367 LLS--IPFTVKMRTGVYQDKKITHTIVPK-MSNWGASLITVHGRSREARYTKSSDWEYIE 423 + +P TVK+R+G + K+I + + GA+ +T+H R+ +T +DW I Sbjct: 133 AAAGDLPVTVKIRSG-WNHKQINAPDFARLLVAHGAAAVTIHARTWSDGFTGRADWAVI- 190 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478 + A PV GNGDI SYE + M A GVMIGRGAL PW+F EQ Sbjct: 191 AAVKRAVSVPVIGNGDIGSYEQALAM-MAATGCDGVMIGRGALGAPWVFTPGAEQ 244 >UniRef50_Q2RZL4 Cluster: NifR3 family enzyme; n=1; Salinibacter ruber DSM 13855|Rep: NifR3 family enzyme - Salinibacter ruber (strain DSM 13855) Length = 443 Score = 128 bits (308), Expect = 5e-28 Identities = 74/238 (31%), Positives = 118/238 (49%), Gaps = 4/238 (1%) Query: 241 IDWNNK-LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE 299 +D++++ L+L+P+ V + PFR +CK +GAD+ E LL+ + E ++ + E Sbjct: 70 LDFDDRPLFLAPMEDVSDPPFRILCKRYGADMMYTEFVSSAGLLREQEHEHQKLEIFDEE 129 Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359 G Q+ G + ++ + D ID+N GCP+ I +K GG+G++ L + Sbjct: 130 RPIGIQVWGGGIDEVRNATPMV-DAAGPDVIDINFGCPVRKIVQKDGGAGVLRNLDKMRN 188 Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419 + + P TVK R G D + + + G + +TVH R+RE +Y + W Sbjct: 189 ITAAVMEEATRPVTVKTRLGWDDDSIHIVDVARMLEDMGVAALTVHARTREQKYKGDARW 248 Query: 420 EYIETCAQAAT-PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 E++ T + T P GNGD E +E V GVM+GRGAL PWIF K Sbjct: 249 EWLRTIKEEGTRDMPFIGNGDALDPE-AIEAMFEETGVDGVMLGRGALGNPWIFERAK 305 >UniRef50_Q2IG49 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=2; Anaeromyxobacter|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Anaeromyxobacter dehalogenans (strain 2CP-C) Length = 352 Score = 128 bits (308), Expect = 5e-28 Identities = 71/231 (30%), Positives = 113/231 (48%), Gaps = 3/231 (1%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305 + +L+PL V + PFR IC+ GA EM L+ G Q + + R ED F Q Sbjct: 11 RYFLAPLAGVSDRPFRAICRRMGASFAYTEMVSAHGLMHGALQTSSYLDREPDEDPFAVQ 70 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 I + P ++ + A ++ ID+N+ CP+ + G G+ M +E +VR Sbjct: 71 IFASEPDVLARGA-VVAVQAGAGMIDVNMACPVKKVCGSGAGAAMGRDPRKVEEAVRAIR 129 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425 + +P TVK+R G + + + GA+ + +HGR+R Y+ + WE + Sbjct: 130 AAVPVPVTVKIRAGWDEGEVNCVDVARAAEAGGAAAVALHGRTRSQLYSGKARWELVRAV 189 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 QA PV G+GD+++ D V MR+ V++ RGA PWIF E+K Sbjct: 190 KQAVA-IPVLGSGDVWTAGDAVRMRE-ETGCDAVLVARGACGNPWIFRELK 238 >UniRef50_A6CBK4 Cluster: Predicted TIM-barrel enzyme, possibly dehydrogenase, nifR3 family protein; n=1; Planctomyces maris DSM 8797|Rep: Predicted TIM-barrel enzyme, possibly dehydrogenase, nifR3 family protein - Planctomyces maris DSM 8797 Length = 365 Score = 127 bits (306), Expect = 9e-28 Identities = 85/264 (32%), Positives = 132/264 (50%), Gaps = 10/264 (3%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLKGLKQEWALVKRHETEDLFG 303 ++ LSPL NLPFRRI +E G + ++ LL+G ++ L + + F Sbjct: 28 SRYLLSPLAGYTNLPFRRIVRELGGVGLATTDLVNARGLLEGSEKTLQLTQTCPEDSPFA 87 Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 QI G+ P + AQLL E+ + ID+N+GCP++ I K G G+ MM R + V+ Sbjct: 88 VQIFGSEPQQMKDAAQLL-ESRGVHSIDINMGCPVNRIVKGGAGASMMCRPSDTVSLVQT 146 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPK-MSNWGASLITVHGRSREARYTKSSDWEYI 422 + + IP +VKMR G + D +++ + G + +HGR+RE + + + I Sbjct: 147 VVEAVKIPVSVKMRLG-WDDSELSAPFFSREFEKVGVVAVAIHGRTREQGFRGVVNHDGI 205 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI---KEQK 479 +A PV GNGD+ + + M K GV IGRGAL PWIF ++ ++ Sbjct: 206 RRVVEAVDSIPVIGNGDVTNVAEADFMLKTTGCA-GVSIGRGALANPWIFRQLVQWEQTG 264 Query: 480 IWDISSK--DRFEILKKYSNYGLE 501 +D DR E+L + Y LE Sbjct: 265 TYDPPGNFDDRLELLLRQFRYLLE 288 >UniRef50_Q9Z7D8 Cluster: Predicted oxidoreductase; n=7; Chlamydiaceae|Rep: Predicted oxidoreductase - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 335 Score = 126 bits (304), Expect = 2e-27 Identities = 91/282 (32%), Positives = 134/282 (47%), Gaps = 7/282 (2%) Query: 239 KTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHET 298 K I + + +PL + P+R + + + EM E +L ++ L+ +E Sbjct: 8 KNILLRSSIVYAPLAGFSDYPYRCMSALYQPGLMFCEMVKVEGILYAPERTSKLLDYNEN 67 Query: 299 EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALE 358 GAQ+CG+NP + A++L E D IDLN GCP D I K G GSG++ + Sbjct: 68 MRPIGAQLCGSNPETSGEAAKIL-EGLGFDLIDLNCGCPTDKITKDGSGSGLLKTPELIG 126 Query: 359 TSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSD 418 + +SIP TVK+R+G + V + + GAS + VHGR+R Y S Sbjct: 127 RILDKIINSVSIPVTVKIRSGWDMEHINVEDTVRIIRDAGASAVFVHGRTRAQGYHGPSK 186 Query: 419 WEYIETC-AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 EYI A A PV+GNGDIFS E M + GV++ RG L PWI +I Sbjct: 187 QEYISRAKAAAGKEFPVFGNGDIFSPEAAQAM--LTTGCDGVLVARGTLGAPWIGKQI-- 242 Query: 478 QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLE 519 Q S ++ +K+ + + LEH +S +FL E Sbjct: 243 QDYLTTGSYEKIPFIKRKAAF-LEHMRLVEDYYQSETKFLSE 283 >UniRef50_Q5M689 Cluster: Possible transcriptional regulator; n=20; Streptococcus|Rep: Possible transcriptional regulator - Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) Length = 350 Score = 126 bits (304), Expect = 2e-27 Identities = 73/231 (31%), Positives = 118/231 (51%), Gaps = 2/231 (0%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 ++ L+P+ V N FR I KEF A + EM + LL ++ ++ E E Sbjct: 42 HRTVLAPMAGVTNSAFRTIAKEFSAGLVVMEMISEKGLLYNNEKTLHMLHIDENEHPMSI 101 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G + + + A +Q NT+ D +D+N+GCP++ + K G+ + + V+ Sbjct: 102 QLFGGDAEGLKRAADFIQTNTKADIVDINMGCPVNKVVKNEAGAKWLKDPDKIYHIVKEV 161 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 + +L IP TVKMRTG + D + + G S + +HGR+RE YT D E + Sbjct: 162 TSVLDIPLTVKMRTG-WSDSDLAVENALAAESAGVSALAMHGRTREQMYTGHCDHETLAR 220 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 A+A T P GNGD+ + +D ++ V VM+GR A+ P+IF +I Sbjct: 221 VAKAITKIPFIGNGDVRNVQD-AKLMIEELGVDAVMVGRAAMNNPYIFTQI 270 >UniRef50_Q74EF7 Cluster: Dihydrouridine synthase family protein; n=2; Deltaproteobacteria|Rep: Dihydrouridine synthase family protein - Geobacter sulfurreducens Length = 325 Score = 125 bits (302), Expect = 3e-27 Identities = 74/230 (32%), Positives = 116/230 (50%), Gaps = 4/230 (1%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N L L+P+ + NLPFR + +E GA + EM L++ K+ + L++ + G Sbjct: 14 NNLILAPMAGITNLPFRLLAREQGAGLCFTEMVSVNGLVREGKKSFELLRSVPGDRPLGI 73 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G++P ++ +VA + +L ID+N+GCP+ + G GS +M + VR Sbjct: 74 QLFGDDPDVMGRVAATVDGYGDL--IDINMGCPVKKVVGTGAGSALMREPDKVRAIVRAV 131 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 + +P TVK+R+G + I G + +T+H RSR + ++DW + Sbjct: 132 RRATRLPLTVKIRSGWSCEDANFIQIARIAEEEGCNAVTLHPRSRAQMFEGTADWTKLAE 191 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 QA PV G+GD+FS D M GVMI RGAL PWIF + Sbjct: 192 LKQAVA-IPVIGSGDLFSAADVAAMLD-RTGCDGVMIARGALGNPWIFRQ 239 >UniRef50_A2FJB5 Cluster: TIM-barrel protein, nifR3 family protein; n=1; Trichomonas vaginalis G3|Rep: TIM-barrel protein, nifR3 family protein - Trichomonas vaginalis G3 Length = 301 Score = 125 bits (302), Expect = 3e-27 Identities = 73/221 (33%), Positives = 119/221 (53%), Gaps = 5/221 (2%) Query: 257 NLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITK 316 ++ FR + E GAD+T EM +L+ K+ L+ E QI G++P ++ + Sbjct: 6 DIAFREVATEKGADITVTEMVSAMALVYENKKTIDLLDISPKEKKVAVQIFGSDPDVMGE 65 Query: 317 VAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKM 376 A++L + + ++D+N+GCP I K GS ++ + V+ K + P T K+ Sbjct: 66 AARILNDY-DFSYVDINMGCPAPKIVKNNSGSHLLSNPSLVYDIVKSVVKNSNKPVTAKV 124 Query: 377 RTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYG 436 R G+ + + + GAS +TVHGR+RE YT +DW++I+ + PV G Sbjct: 125 RKGIGGVSSMK--AIKNIEAAGASFVTVHGRTREEYYTGKADWDFIKE-VKENVKIPVIG 181 Query: 437 NGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 NGD+ S ED +E + V G+ IGRGA+ P+IFN+I+E Sbjct: 182 NGDVDSPEDAIEKINYS-KVDGLAIGRGAIGNPYIFNQIEE 221 >UniRef50_A5D5Q0 Cluster: TRNA-dihydrouridine synthase; n=5; Firmicutes|Rep: TRNA-dihydrouridine synthase - Pelotomaculum thermopropionicum SI Length = 324 Score = 125 bits (301), Expect = 4e-27 Identities = 74/228 (32%), Positives = 113/228 (49%), Gaps = 3/228 (1%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N + +P+ + + FR + +EFG + C EM ++LL G + +L+ Sbjct: 10 NPVIAAPMAGITDKAFRILAREFGCGLVCTEMVSDQALLHGNPKTCSLLDVAGEAGPVSV 69 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 QI G+N + + A + E+ ID+N+GCP I K G G+ +M VR Sbjct: 70 QIFGSNAACMAEAAGIA-ESRGAGIIDINMGCPTPKIVKNGEGAALMREPEKAARIVRAV 128 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 + + +P TVKMR G + + + GA+ +TVHGR+R Y +DWE I Sbjct: 129 VERVKVPVTVKMRKGWDDNSPNAVELARLAAEAGAAAVTVHGRTRSQLYAGKADWEII-A 187 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 + A PV GNGD+++ +D + M + GVMIGR AL PWIF Sbjct: 188 AVKRAVDVPVIGNGDVWTPQDALAMLE-QTGCDGVMIGRAALGNPWIF 234 >UniRef50_O25427 Cluster: Probable tRNA-dihydrouridine synthase; n=9; Epsilonproteobacteria|Rep: Probable tRNA-dihydrouridine synthase - Helicobacter pylori (Campylobacter pylori) Length = 328 Score = 124 bits (298), Expect = 9e-27 Identities = 80/240 (33%), Positives = 124/240 (51%), Gaps = 8/240 (3%) Query: 241 IDWNNK--LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHET 298 +D+ NK L+L+PL +LPFR + K+FG DVT EM SL+ + ++++ Sbjct: 1 MDFKNKKWLFLAPLAGYTDLPFRSVVKKFGVDVTTSEMVSSHSLVYAFDKTSKMLEKSPL 60 Query: 299 EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALE 358 ED F AQI G+ ++ + + + ++ ID N GCP + G GSG++ L L Sbjct: 61 EDHFMAQISGSKESVVKEAVEKINALEHVNGIDFNCGCPAPKVANHGNGSGLLKDLNHLV 120 Query: 359 TSVRCASKLLSIPFT-VKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSS 417 ++ + S T VK+R G +KKI I +++ + VHGR+R +Y K Sbjct: 121 KLLKTIRENTSKKITSVKVRLGF--EKKIPKEIAHALNDAPVDYVVVHGRTRSDKYQKDK 178 Query: 418 -DWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 D+E I + PV NG+I S + E+ +I G+MIGR AL PWIF +I+ Sbjct: 179 IDYESIALMKKILKK-PVIANGEIDSVKKAFEVLQIT-QADGLMIGRAALRAPWIFWQIR 236 >UniRef50_Q1VN28 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=1; Psychroflexus torquis ATCC 700755|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Psychroflexus torquis ATCC 700755 Length = 338 Score = 123 bits (296), Expect = 2e-26 Identities = 72/235 (30%), Positives = 116/235 (49%), Gaps = 4/235 (1%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 ++L+P+ V +L +R + KE GAD T E L + W V+ E F QI Sbjct: 14 IFLAPMAGVTDLAYRLLAKECGADFTVTEFTAASGLTRKNTNSWLKVETDPREKPFIPQI 73 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 G + + K +L++ + D ID+N GCP + + G+ ++ + + VR + Sbjct: 74 FGGDISEMAKTVGMLEDRS--DVIDINFGCPAPKVCRNDAGAALLRDPDKVVSMVRRCIE 131 Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426 ++P TVKMR G I ++++ G I VHGR+ RY+ +DW+ I+ + Sbjct: 132 STNVPITVKMRLGTGSGPNTALEISKRLADEGVMRICVHGRTLRQRYSGIADWDQIKEIS 191 Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIW 481 + PV NGD+ + E+ A G+MIGRGA+ +P IF+EIK W Sbjct: 192 N-SVDIPVIANGDVVDTKS-AELCLEATNAGGLMIGRGAIGRPTIFHEIKHGMGW 244 >UniRef50_Q9ZED2 Cluster: Probable tRNA-dihydrouridine synthase; n=39; Proteobacteria|Rep: Probable tRNA-dihydrouridine synthase - Rickettsia prowazekii Length = 327 Score = 123 bits (296), Expect = 2e-26 Identities = 81/290 (27%), Positives = 143/290 (49%), Gaps = 15/290 (5%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVK-RHETE 299 I+ ++ + L+P++ V +L FR++ K FGA + EM +++ +Q H+ Sbjct: 7 IELSSNVILAPMSDVTDLEFRKLVKRFGAGLVVSEMIASRAMIMKSRQSMQKCAIMHDDP 66 Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359 Q+ G P +I + A++ E+ IDLN GCP + GS +M Sbjct: 67 TSACVQLAGCEPDVIAEAAKM-NEDMGAKIIDLNFGCPAKKVVGGYAGSALMRDEQLAAK 125 Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419 K + IP TVKMR G + + T+ +N G ++TVHGR+R Y+ +++W Sbjct: 126 IFEATVKAVKIPVTVKMRIGWDDNTRNAPTLAKIAANSGVQMVTVHGRTRCQFYSGNANW 185 Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI---- 475 ++I T + A PV NGDI ++ E + G+M+GRG KPW+ ++I Sbjct: 186 DFIRT-VKEAVKIPVIANGDITNFAKAKEALQ-RSGADGIMVGRGVYGKPWLISQIAYYL 243 Query: 476 ---KEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLS 522 KE+ I+ ++ +I+ K+ + ++++G GV R+ ++ W S Sbjct: 244 KTGKEKPAPSIA--EQLDIITKHYDAIIDYYGKSV-GVPIARKHII-WYS 289 >UniRef50_A6EDJ3 Cluster: Probable TIM-barrel protein, NifR3 family; n=1; Pedobacter sp. BAL39|Rep: Probable TIM-barrel protein, NifR3 family - Pedobacter sp. BAL39 Length = 335 Score = 122 bits (294), Expect = 3e-26 Identities = 69/231 (29%), Positives = 112/231 (48%), Gaps = 3/231 (1%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 L L+P+ V + PFR +CK+ G D+ E E L++ + A + E E G QI Sbjct: 15 LLLAPMEDVSDPPFRFVCKQSGVDMMYTEFISSEGLIRDAAKSRAKLDIFEYERPIGIQI 74 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 G+ + + ++ D +D+N GCP+ + +G GS ++ + + + Sbjct: 75 FGSEIDHMREATEIASMAGP-DLMDINYGCPVKQVACRGAGSALLQDIDKMVEMTKAVVN 133 Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI-ETC 425 +P TVK R G + K + ++ + G +T+HGR+R Y +DW I E Sbjct: 134 ATHLPVTVKTRLGWDDNTKNVEEVAERLQDIGIQGLTIHGRTRAQMYKGEADWTLIREIK 193 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 P++GNGD+ S + + R + V G+MIGR A+ PWIF EIK Sbjct: 194 RNPRIKIPIFGNGDVDSIQKAADWR-LEYEVDGIMIGRAAIGYPWIFREIK 243 >UniRef50_P37567 Cluster: Probable tRNA-dihydrouridine synthase 1; n=31; Bacilli|Rep: Probable tRNA-dihydrouridine synthase 1 - Bacillus subtilis Length = 333 Score = 122 bits (293), Expect = 4e-26 Identities = 72/231 (31%), Positives = 112/231 (48%), Gaps = 2/231 (0%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETED 300 I N++ L+P+ V N FR KEFGA + C EM +++L + ++ E E Sbjct: 7 IQLKNRVVLAPMAGVCNSAFRLTVKEFGAGLVCAEMVSDKAILYNNARTMGMLYIDEREK 66 Query: 301 LFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS 360 QI G + + A+ + +NT D ID+N+GCP+ I K G+ + + Sbjct: 67 PLSLQIFGGKKETLVEAAKFVDQNTTADIIDINMGCPVPKITKCDAGAKWLLDPDKIYEM 126 Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420 V ++ P TVKMR G +D + G + +HGR+R Y +++W+ Sbjct: 127 VSAVVDAVNKPVTVKMRMGWDEDHIFAVKNAQAVERAGGKAVALHGRTRVQMYEGTANWD 186 Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWI 471 I+ Q+ + PV GNGD+ + +D M V GVMIGR AL PW+ Sbjct: 187 IIKEVKQSVS-IPVIGNGDVKTPQDAKRMLD-ETGVDGVMIGRAALGNPWM 235 >UniRef50_A4TZK1 Cluster: Dihydrouridine synthase, DuS; n=4; Proteobacteria|Rep: Dihydrouridine synthase, DuS - Magnetospirillum gryphiswaldense Length = 335 Score = 121 bits (291), Expect = 6e-26 Identities = 76/285 (26%), Positives = 142/285 (49%), Gaps = 13/285 (4%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N + L+P++ V ++P RR+ K GA + EM +++++ +Q + E Sbjct: 18 NPVILAPMSGVTDMPCRRLVKRMGAGLVVSEMIASQAMIRANRQTMKMASNCAEEHPMSV 77 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG-GGSGMMHRLPALETSVRC 363 Q+ G P ++ + A+ + + ID+N+GCP+ + KG GS +M + Sbjct: 78 QLAGCEPEVMAEAAR-MNADRGAAIIDINMGCPVKKVAVKGEAGSALMKDEILAGQLMEA 136 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 + + +P T+K R G ++ + G ++T+HGR+R+ YT ++DW+++ Sbjct: 137 TVRAVDVPVTLKCRMGWDHNRLNAPRLARIAQESGIKMVTIHGRTRQQFYTGTADWKFVR 196 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIFNEIKE----- 477 + A PV NGDI + +D + R +A + GVMIGRG+ +PW ++ Sbjct: 197 Q-VKDAVDIPVIVNGDIETIDDAI--RALAESGADGVMIGRGSYGRPWFPGQVAHYLATG 253 Query: 478 QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLS 522 ++ D + + IL ++ + L H+G+DT GV R+ + W S Sbjct: 254 ERPADPALDQQLAILLEHFDDMLSHYGTDT-GVRMARKH-IAWYS 296 >UniRef50_A4EC62 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 347 Score = 120 bits (289), Expect = 1e-25 Identities = 68/230 (29%), Positives = 103/230 (44%), Gaps = 4/230 (1%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308 ++P+ V + +R +C+ GA++ EM L + W LV + E Q+ G Sbjct: 21 MAPMAGVTDPAYRIMCRRRGANLAYSEMVSVAGLAYASNKTWRLVLPADEEQQICVQLFG 80 Query: 309 NNPYIITKVAQLLQENT--ELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 + P ++E L ID+N+ CP + KG GS +M E V A Sbjct: 81 SKPEQFASAVAAVEERVGDRLSLIDINMACPARKVVTKGEGSALMRTPDLAEKIVEAAVG 140 Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426 +P TVK+R G Y + + T + GA+ + VHGR YT +DW ++ A Sbjct: 141 AAHVPVTVKIRKGFYAEDRNAATFAQMLEGAGAAAVAVHGRCATQLYTGQADWSVVDEVA 200 Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 A PV G+GD+FS ED E + V I RG PW+F + + Sbjct: 201 D-AVEIPVIGSGDVFSAEDAAEHLQ-GSGASAVFIARGIYGNPWVFGDAR 248 >UniRef50_O67533 Cluster: Probable tRNA-dihydrouridine synthase; n=1; Aquifex aeolicus|Rep: Probable tRNA-dihydrouridine synthase - Aquifex aeolicus Length = 316 Score = 120 bits (289), Expect = 1e-25 Identities = 73/251 (29%), Positives = 129/251 (51%), Gaps = 10/251 (3%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK-GLKQEWALVKRHETEDLFGA 304 ++ L+P+ + + FRR+C+ GAD T E+ +L+ G+ + A E E Sbjct: 7 EVILAPMASYTHSAFRRLCRRLGADRTYTELISAVGVLRNGIPMKLAYFT--EEERPIHI 64 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC- 363 Q+ G+NP I + + ++ + + DFID+N GC + + + M+ P + V+ Sbjct: 65 QVFGSNPEEIAQASVVIAKELKPDFIDINFGCSVPKVLRNKAAGYMLQCPPLMGEVVKET 124 Query: 364 --ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 A K IP + K+R G +D+ IV ++ G SLI +H R+ + ++ + W Sbjct: 125 VEALKPYGIPVSAKIRLGFEKDE--VERIVEELQKAGVSLIAIHARTAKQGFSGKALWHR 182 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIW 481 I+ + A+ P+ G+GD+ S+ D M + GVM+GR AL PWIF E KE++ Sbjct: 183 IKEAKKVAS-VPIIGSGDVKSWRDIERMFE-ETECDGVMVGRAALSNPWIFKEFKEKRDI 240 Query: 482 DISSKDRFEIL 492 ++ K+R + + Sbjct: 241 EVGLKERMDFI 251 >UniRef50_Q8G7W8 Cluster: Possible NifR3-like protein; n=4; Bifidobacterium|Rep: Possible NifR3-like protein - Bifidobacterium longum Length = 414 Score = 119 bits (287), Expect = 2e-25 Identities = 76/250 (30%), Positives = 118/250 (47%), Gaps = 6/250 (2%) Query: 231 IKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGAD-VTCGEMALCESLLKGLKQE 289 + + P + I + LSP+ V N PFR IC+E+G D + EM +L+ + Sbjct: 33 VHIAPVQLGNITVPTPVVLSPMAGVTNWPFRVICEEYGPDGLYVAEMITARALVAHNPKA 92 Query: 290 WALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSG 349 L ++E + Q+ G NP I + A+++ + D +DLN GCP+ + ++GGGS Sbjct: 93 LRLCHFAKSEKIRSLQLYGVNPSITEQAAKIVVDGNMADHVDLNFGCPVPKVTRRGGGSA 152 Query: 350 MMHR---LPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHG 406 + + L V + IP T K+R G+ + + G +T+H Sbjct: 153 LPWKTDIFTELLQRVVAVCEPAGIPVTAKIRVGIDHNHETFLEAGHIAQEEGCKAVTLHA 212 Query: 407 RSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGAL 466 R+ Y SDW I + PV+GNGDI+ ED +EM + GV IGRG Sbjct: 213 RTTAEYYGGHSDWSRIGELKEHLN-IPVFGNGDIWGAEDALEMVR-ETGCDGVAIGRGCQ 270 Query: 467 IKPWIFNEIK 476 +PW+F IK Sbjct: 271 GRPWLFANIK 280 >UniRef50_A5EVV4 Cluster: Dihydrouridine synthase; n=1; Dichelobacter nodosus VCS1703A|Rep: Dihydrouridine synthase - Dichelobacter nodosus (strain VCS1703A) Length = 318 Score = 117 bits (282), Expect = 8e-25 Identities = 67/230 (29%), Positives = 119/230 (51%), Gaps = 6/230 (2%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFG--AQI 306 L+P+ + +LP+R +C+ FG+ T EM + + L + + + F Q+ Sbjct: 16 LAPMAGISDLPYRSLCQRFGSHYTIAEMVDARPQFLAMPES-QLRLQFDDDARFPKIVQL 74 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 G +PY++ + AQ++Q D ID+N+GCP + K+ GS ++ LP +E + ++ Sbjct: 75 VGGDPYLMAETAQVMQA-LGCDVIDINMGCPAKKVGKQNAGSALLSDLPQVEKILAQVTR 133 Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426 ++SIP T+K R G + T+ N G + +TVHGR+R R+ ++ ++ I Sbjct: 134 VVSIPVTLKTRLGFNEQTMTIETVAKIAENTGVAALTVHGRTRAQRFNGTAHYDEIGR-V 192 Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 +A T P+ NGDI + ++ + GVMIGR A PW+ ++ Sbjct: 193 KAQTSLPIIVNGDITTTAQAQDLIQ-QFGFDGVMIGRAACGNPWLLAHMR 241 >UniRef50_Q6A959 Cluster: TIM-barrel enzyme, NifR3 family; n=1; Propionibacterium acnes|Rep: TIM-barrel enzyme, NifR3 family - Propionibacterium acnes Length = 411 Score = 116 bits (279), Expect = 2e-24 Identities = 73/254 (28%), Positives = 127/254 (50%), Gaps = 9/254 (3%) Query: 229 DLIKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQ 288 D + L+ T+ + + L+P+ V N FR++C E GA + EM L+ G + Sbjct: 34 DPLTLIAPSGGTVSVDTPVVLAPMAGVTNAAFRQLCAEQGAGLYVCEMITSRGLVYGDHK 93 Query: 289 EWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGS 348 ++ E ED+ Q+ G +P ++ + +L E ++ +DLN GCP+ + +KGGG Sbjct: 94 THGMLAFAECEDVRSVQLYGVDPGMVGEATSILCEKYGVNHVDLNFGCPVPKVTRKGGGG 153 Query: 349 GM---MHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITV 404 + + R A+ ++ A +P TVK R G+ + IT+ + + + GA+ + + Sbjct: 154 VLPWKLDRFAAVVSAAVQAGDAHGVPVTVKTRIGI-DPEHITYIDSARAAVDSGAAAVCL 212 Query: 405 HGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGR 463 H R+ Y S W+ I + PV GNGDI+ D + M + T GV +GR Sbjct: 213 HARTVAEAYAGHSHWDAIGELVK-TVDVPVIGNGDIWEASDAMAM--VGQTGCAGVEVGR 269 Query: 464 GALIKPWIFNEIKE 477 G L +PW+F ++ + Sbjct: 270 GCLGRPWLFRDLAD 283 >UniRef50_A4M5I1 Cluster: Dihydrouridine synthase, DuS; n=1; Petrotoga mobilis SJ95|Rep: Dihydrouridine synthase, DuS - Petrotoga mobilis SJ95 Length = 301 Score = 115 bits (277), Expect = 3e-24 Identities = 75/278 (26%), Positives = 139/278 (50%), Gaps = 11/278 (3%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N++ L+P+ + PFR IC+ FGA T EM +S+++ ++ ++ + + ED G Sbjct: 4 NQIGLAPMADYTDYPFREICRRFGAKFTFTEMISVDSIIRENEKVEKMLPQ-KGEDNIGV 62 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ GN + A+ +Q +ID+N CP++ + KKG G+ ++ L V Sbjct: 63 QLFGNETTKFIEAAKSIQHLAS--WIDINAACPVNKVVKKGSGAALLKNPKLLGDIVFNL 120 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 K + +P VK+R G D+ + + GA I VHGR+R Y+ ++ E ++ Sbjct: 121 KKSIDLPVGVKVRLG--YDQINIEEVAETVEKAGADYIIVHGRTRSQMYSGIANREILKK 178 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDIS 484 +A P+ +GD+FS +D ++ + V++ RGA+ PWIF + D Sbjct: 179 -LKAKITIPLGASGDVFSKKD-IDDYLLNYGADFVLVARGAIGNPWIFTKNNYNPTID-- 234 Query: 485 SKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLS 522 +R + ++ +E +GS+ V+ R+ L+++ S Sbjct: 235 --ERIDTCLEHLKLMIEFYGSEVYAVKKFRKVLMKYFS 270 >UniRef50_A6PPM6 Cluster: Dihydrouridine synthase, DuS; n=1; Victivallis vadensis ATCC BAA-548|Rep: Dihydrouridine synthase, DuS - Victivallis vadensis ATCC BAA-548 Length = 343 Score = 115 bits (276), Expect = 4e-24 Identities = 75/278 (26%), Positives = 131/278 (47%), Gaps = 4/278 (1%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N L ++PL+ +LP+RR + G EM SL ++ +++R E+ G Sbjct: 16 NALLMAPLSGFTDLPYRRAARAGGCRFAFTEMVDVASLTYARERSAGMLRRGPEEEFLGV 75 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G + I + A ++ E E +D N+GCP+ + KKG G+ + L A Sbjct: 76 QLVGADHEFIRRAADVVNEY-EFSVVDFNLGCPVPKVAKKGAGAELGRHLDAALACFAII 134 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 ++ P T K+R +D T + ++ GA ITVHGR +EA Y+ ++ I Sbjct: 135 AERSRHPVTAKIRIVDAEDPAPTLALAKGLAELGAQAITVHGRIKEAFYSGPVNFGMIRA 194 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDIS 484 +A V NG + Y E+R+ VM+ RGA+ PW+FNE+ + Sbjct: 195 VREALPGVQVIANGGVTGRVKYQEIRR-ETGCSLVMLARGAMGNPWLFNELSLGDAYVPP 253 Query: 485 SKDR-FEILKKYSNYGLEHWGSDTQGVESTRRFLLEWL 521 D F +++++ +E +G ++ + R+ L ++L Sbjct: 254 DIDEWFGVIREHVEGMIELYGEES-AMRMARKILHDYL 290 >UniRef50_Q9CLW3 Cluster: tRNA-dihydrouridine synthase B; n=17; Pasteurellaceae|Rep: tRNA-dihydrouridine synthase B - Pasteurella multocida Length = 332 Score = 115 bits (276), Expect = 4e-24 Identities = 64/228 (28%), Positives = 115/228 (50%), Gaps = 3/228 (1%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N+++L+P+ + + PFRRIC +GA +T EM + ++ + H+ + Sbjct: 10 NRIFLAPMAGITDQPFRRICTHYGAGLTFSEMMSTNPQVWHTEKSKLRLAHHQEAGINAV 69 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 QI G +P + K AQ+ E + ID+N+GCP + +K GS ++ ++ + Sbjct: 70 QIAGCDPDEMAKAAQINVEYGA-EIIDINMGCPAKKVNRKMAGSALLQYPDLVKQILNKV 128 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 K +++P T+K+RTG +D + I G +T+HGR+R + ++++ I+ Sbjct: 129 VKSVTVPVTLKIRTGWDKDNRNCLEIAKIAEQCGIQALTIHGRTRSCMFEGEAEYDNIKA 188 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 + + P+ NGDI S E + +MIGRG+L PW+F Sbjct: 189 VKEQLS-IPIIANGDITSAEKAKYVLDYT-NADAIMIGRGSLGNPWLF 234 >UniRef50_A0LJ96 Cluster: Putative TIM-barrel protein, nifR3 family; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Putative TIM-barrel protein, nifR3 family - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 352 Score = 113 bits (273), Expect = 9e-24 Identities = 70/234 (29%), Positives = 117/234 (50%), Gaps = 6/234 (2%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKR-HETEDLFGAQ 305 L L+P+ V + +R + +FGA + EM + L++ + L ++ H Q Sbjct: 24 LVLAPMAGVTDSAYRALMADFGAAMVTTEMVSIQGLVRNQRATLDLCRQQHPVGVPLAVQ 83 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 + G +P ++ + A+L+++ ID+N GCP+ + ++G G+ ++ L V Sbjct: 84 VFGRDPAVMAEAARLVEQGGAA-LIDINAGCPVRKVVRQGAGAILLKDPDRLAAMVEAVK 142 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425 + +S+P TVK+R G + ++ + G ITVHGR+ Y+ +DW I Sbjct: 143 RAVSVPVTVKIRVGWDNAANGVAGLARQLVSAGVDAITVHGRTAAQMYSGRADWSRIAE- 201 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIFNEIKEQ 478 +AA PV GNGD+ S E + R I T GVMIGR +L PW+F I + Sbjct: 202 VKAAVAVPVIGNGDVTSPE--LAERMIHETGCDGVMIGRASLGNPWLFAVISRR 253 >UniRef50_Q2RM54 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=1; Moorella thermoacetica ATCC 39073|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Moorella thermoacetica (strain ATCC 39073) Length = 334 Score = 113 bits (272), Expect = 1e-23 Identities = 74/232 (31%), Positives = 108/232 (46%), Gaps = 6/232 (2%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 L ++P+ + FR + +E GA +T EM + L+ K AL+ Q+ Sbjct: 16 LIMAPMAGYTDRVFRLLAREAGAALTYTEMISAQGLIYNNKNTHALLDLKGEPGPVAVQL 75 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 G P I+ ++ IDLN+GCP I K G GS +M LP V + Sbjct: 76 FGREPEIMAAATRIAVA-AGAAIIDLNMGCPTPKIVKNGEGSALMRDLPRAAAIVAAMVR 134 Query: 367 LLS-IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425 +P TVKMR G +D + GA+ + +HGR+R Y+ +DW Y Sbjct: 135 AAGPVPVTVKMRLGWDEDSINVVEAARAVVYAGAAAVAIHGRTRSQFYSGRADWSYFRR- 193 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIFNEIK 476 + A PV GNGD+ + D V M +A T GVM+GRGA+ PW+ I+ Sbjct: 194 VKEAVDVPVIGNGDVRTARDAVTM--LAETGCDGVMVGRGAVGNPWLLTAIR 243 >UniRef50_A6NW05 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 307 Score = 113 bits (272), Expect = 1e-23 Identities = 72/226 (31%), Positives = 109/226 (48%), Gaps = 9/226 (3%) Query: 255 VGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYII 314 V ++ FR IC+E GA T EM ++L K+ L+K E E AQI G++ + Sbjct: 4 VTDMAFRTICRELGAGYTITEMVSAKALCYQDKKSIPLLKLGEGEHPCAAQIFGSDEKCM 63 Query: 315 TKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL----SI 370 + A + E + D ID+N+GCP+ + G GSG+M ++ +VR A ++ Sbjct: 64 EEAAAIAGEVSGADIIDINMGCPVPKVANSGDGSGLMR---DVDKAVRVAEAVVRGAGER 120 Query: 371 PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAAT 430 P TVK R G + M G S + VHGR+R Y +++W+YI QA + Sbjct: 121 PVTVKFRLGWDKGSINCVEFAKAMEAAGVSAVAVHGRTRTQMYAGTANWDYIREVKQAVS 180 Query: 431 PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 PV NGD+F + + MIGRG PW+F + + Sbjct: 181 -IPVIANGDVFDGPAAAHILRYT-GADMAMIGRGCFGNPWVFQQAR 224 >UniRef50_Q3E0H8 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=5; Chloroflexi (class)|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Chloroflexus aurantiacus J-10-fl Length = 407 Score = 113 bits (271), Expect = 2e-23 Identities = 73/233 (31%), Positives = 115/233 (49%), Gaps = 6/233 (2%) Query: 247 LYLSPLTTVGNLPFRR-ICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305 + L+P+ V + FRR I + G + EM S+ + L+ E Q Sbjct: 85 IILAPMAGVTDSIFRRMILRLGGCGLVSTEMTNAASVSPKALRRHRLLDYLPEERPLTMQ 144 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 I GN+P ++ A+++ E D ID+N GCP + G GS ++ LP +E +R Sbjct: 145 ISGNDPDLVANAARVV-EQLGADIIDINCGCPSPKVTGGGHGSALLRDLPKMERLLRAVR 203 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSN-WGASLITVHGRSREARYTKSSDWEYIET 424 + + IP T+K R G + ++ + K + G S + +H R+RE Y +DW + Sbjct: 204 EAVQIPVTLKFRAG-WDEQSLNFIEAGKRAEAAGVSALALHPRTREQGYKGQADWSRVAA 262 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 QA + PV G+GD+ S D + +R GVMIGRGA+ PWIF +I + Sbjct: 263 LKQAVS-IPVIGSGDVTSAHDAL-IRLRDSGADGVMIGRGAMANPWIFRQIAD 313 >UniRef50_Q0B0N8 Cluster: Putative TIM-barrel protein, NifR3 family; n=2; Clostridiales|Rep: Putative TIM-barrel protein, NifR3 family - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 318 Score = 113 bits (271), Expect = 2e-23 Identities = 70/233 (30%), Positives = 115/233 (49%), Gaps = 3/233 (1%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N++ +P+ V + +R + ++FG + C EM + L+ G + + + Sbjct: 11 NRVCAAPMAGVSDKAYRVLARDFGCGLVCSEMVSDKGLVYGQGRTSKIADSSGEKRPVAV 70 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 QI G+ + A++++E D ID+N+GCP I K G G+ +M + VR Sbjct: 71 QIFGSEAESMATAARIVEE-MGADIIDINMGCPTPKIVKNGEGAALMLDITKSRGIVREV 129 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 +++ +P TVKMR G ++ + K+ G + I +H RSR+ ++ S+DW I+ Sbjct: 130 LRVVKVPVTVKMRKGWDENSINCLELAQKLEEEGVAAICLHPRSRQQFFSGSADWNLIKE 189 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 + PV GNGDI+S +D M VMIGR AL P+IF E E Sbjct: 190 -MKKELKIPVIGNGDIWSADDAQRMIDFT-GCDAVMIGRAALGNPFIFRETFE 240 >UniRef50_Q489F6 Cluster: NifR3/Smm1 family protein; n=2; Proteobacteria|Rep: NifR3/Smm1 family protein - Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibriopsychroerythus) Length = 338 Score = 112 bits (270), Expect = 2e-23 Identities = 68/236 (28%), Positives = 118/236 (50%), Gaps = 3/236 (1%) Query: 240 TIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE 299 T N+++ L+P+ + + PFR++C + GA + EM + ++ + + Sbjct: 5 TYQLNSQVMLAPMAGITDQPFRQLCCQLGAGLAVSEMLSSNPKVWNTEKSKLRMLHGDAA 64 Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359 + QI G+ P + A++ +N ID+N+GCP + KK GS ++ +E Sbjct: 65 GIRSVQIAGSCPDELAFAAKVNADNGA-QIIDINMGCPAKKVNKKLAGSALLREPAQVER 123 Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419 V+ + IP T+K+RTG +D + I N G + + VHGR+R Y ++++ Sbjct: 124 IVQSVVNAVDIPVTLKIRTGWCEDTRNGIEIAKIAENSGIASLAVHGRTRNDFYKGNAEY 183 Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 + I+ + A PV NGDI S E +++ +M+GRGA +PWIF EI Sbjct: 184 DTIK-AIKLAISIPVVANGDITSPEKALQVLD-HTGADAIMVGRGAQGRPWIFREI 237 >UniRef50_A6BZR9 Cluster: Predicted TIM-barrel enzyme, possibly dehydrogenase, nifR3 family protein; n=1; Planctomyces maris DSM 8797|Rep: Predicted TIM-barrel enzyme, possibly dehydrogenase, nifR3 family protein - Planctomyces maris DSM 8797 Length = 355 Score = 112 bits (270), Expect = 2e-23 Identities = 74/234 (31%), Positives = 113/234 (48%), Gaps = 3/234 (1%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCG-EMALCESLLKGLKQEWALVKRHETEDLFG 303 ++ +L+PL FR +E G C ++ L LL G ++ AL+ + Sbjct: 23 SRYFLAPLAGYTQHAFRVAIRELGGVGLCTTDLVLASHLLSGSRKSKALLTTSPADRPLT 82 Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 QI G + A+ L+++ +DLN+GCP+ I GGG+ +M A V Sbjct: 83 IQIFGGITAELVAAARWLEQHGYAA-VDLNMGCPMAKINGNGGGARIMCAPDAACQLVAE 141 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 +SIP TVKMR G +D + + G + ITVHGR+R + + D + I Sbjct: 142 VVDAVSIPVTVKMRLGWDRDSITAPLLAREFEQAGVAAITVHGRTRNQGFGGTVDLQGIR 201 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 +A PV GNGD+ + ED MR+ + V IGRGA++ PWIF +I + Sbjct: 202 QTVEAVQQIPVIGNGDVCTVEDAFRMRE-QTGCEAVSIGRGAMLDPWIFRKISQ 254 >UniRef50_A6DCX2 Cluster: tRNA-dihydrouridine synthase B; n=1; Caminibacter mediatlanticus TB-2|Rep: tRNA-dihydrouridine synthase B - Caminibacter mediatlanticus TB-2 Length = 311 Score = 112 bits (269), Expect = 3e-23 Identities = 72/259 (27%), Positives = 128/259 (49%), Gaps = 8/259 (3%) Query: 248 YLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQIC 307 +L+PL +LPFR + KEFG D+T EM ++ ++ ++++ E + QI Sbjct: 14 FLAPLAGYTDLPFRSVVKEFGCDMTFSEMINANAIAFNNEKTKKMMQKSSKETPYFIQIA 73 Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM--HRLPALETSVRCAS 365 NN K +++ E +D ID+N+GCP++ + G G ++ L+ V Sbjct: 74 ANNVENAIKAVEIINEIPWIDGIDINLGCPVNKARRSGYGGVLLKDENKEKLKEIVSAII 133 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425 K + KMR G ++ + + + G +TVHGR+ + Y +++++ I+ Sbjct: 134 KTSKKIVSAKMRLG--YNEVVAVDRAKMLEDLGIKFLTVHGRTVKQMYKGNANYKEIKKV 191 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISS 485 + PV NGDI Y+ E+ + GV IGRG + KPWIF E+K+Q +I+ Sbjct: 192 VKEVN-IPVIANGDITDYKKAKEVLEYT-EANGVAIGRGVIGKPWIFLEMKQQ--GEITP 247 Query: 486 KDRFEILKKYSNYGLEHWG 504 + E++ + +E +G Sbjct: 248 YQKKEVILTHFKAMIEWYG 266 >UniRef50_Q8PX79 Cluster: NifR3-like protein; n=5; Archaea|Rep: NifR3-like protein - Methanosarcina mazei (Methanosarcina frisia) Length = 323 Score = 111 bits (268), Expect = 4e-23 Identities = 71/233 (30%), Positives = 118/233 (50%), Gaps = 4/233 (1%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFG 303 + L L+P+ V NL FR +C+ +GAD+T EM ++LL ++ + E + FG Sbjct: 14 SGNLLLAPMADVTNLAFRLLCRRYGADLTYTEMINVDALLNESRKSFIKGLSSEEDRPFG 73 Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 Q+ G P + + A ++E + ID+N+GCP I G GS +++ + + + Sbjct: 74 VQLVGGCPDKLKRAALFIEEEYRPEIIDVNMGCPARCITGAGCGSALLNSPELVYSIILE 133 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 ++ L P + K+R ++K T I + GAS +TVHGR+ Y+ +S+ E I Sbjct: 134 LTESLDTPVSAKIRLLGREEK--TLEIARLIEKAGASAVTVHGRTAAQMYSGNSNLEGIR 191 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 + PV NGD+ E+ E G+MIGR A+ P+IF +I+ Sbjct: 192 AVKNELS-IPVIANGDV-KDEESAERTLELTGCDGLMIGRAAMGNPFIFKKIR 242 >UniRef50_Q6M9N8 Cluster: Putative uncharacterized protein; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Putative uncharacterized protein - Protochlamydia amoebophila (strain UWE25) Length = 297 Score = 111 bits (267), Expect = 5e-23 Identities = 61/174 (35%), Positives = 92/174 (52%), Gaps = 4/174 (2%) Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 G Q+CG+ P I + A++++E D +DLN GCP+D I K G GSG++ + P L + Sbjct: 28 GGQLCGSKPSIAGQAAKIIEE-LGFDIVDLNCGCPVDKITKDGSGSGLL-KTPELIGEIV 85 Query: 363 CAS-KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 C + IP TVK+R G + + IV + GA I +HGR+R+ Y ++WEY Sbjct: 86 CNMVSAVKIPVTVKIRAGWDEQQIQVENIVQIVEQAGAQAICIHGRTRQQGYRGPANWEY 145 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 I+ AA + GNGD+ +M V++ RG L +PWI +I Sbjct: 146 IKRGKLAAKSIKIIGNGDVLDGPSAAKM-FCETGCDAVLVARGTLGQPWIVQDI 198 >UniRef50_Q6SFW7 Cluster: NifR3/Smm1 family protein; n=1; uncultured bacterium 578|Rep: NifR3/Smm1 family protein - uncultured bacterium 578 Length = 322 Score = 111 bits (267), Expect = 5e-23 Identities = 68/233 (29%), Positives = 115/233 (49%), Gaps = 5/233 (2%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCES-LLKGLKQEWALVKRHETEDLF 302 ++K+ L+P+ + PFR IC+E GA +T EM + + LL K + L R E + Sbjct: 9 SSKVLLAPMAGTSDKPFRMICREQGAALTTSEMVVMQKHLLNTNKSKHRLDFRSEQSPI- 67 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 QI G+ + + A+ E D ID+N+GCP + K GS +M +E ++ Sbjct: 68 SIQIAGSESQELAESAKQALE-FGADIIDINMGCPAKKVCNKAAGSALMKNEKLVEDIIK 126 Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 ++IP T+KMRTG ++ K TI + G ++ +HGR+R +Y ++++ + Sbjct: 127 AVVNAVNIPVTLKMRTGWNEENKNAPTIAKIAEDNGIKMLAIHGRTRAQKYNGDAEYDTV 186 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 + + PV NGDI S + ++ VM+GR PW+ +I Sbjct: 187 KK-IKGIVSIPVVANGDITSAQKAKKVLDYT-GADAVMLGRATQGNPWLVGQI 237 >UniRef50_Q6MAU6 Cluster: Putative uncharacterized protein yohI; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Putative uncharacterized protein yohI - Protochlamydia amoebophila (strain UWE25) Length = 326 Score = 109 bits (261), Expect = 3e-22 Identities = 83/268 (30%), Positives = 132/268 (49%), Gaps = 23/268 (8%) Query: 247 LYLSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLKGLKQEWALVKRHETEDLF--- 302 L L+P+ VG+ FR+ G D C E S +L R+E + F Sbjct: 14 LILAPMEGVGDRSFRKAMASVGGFDEACTEFMRVPSNA----HVPSLANRYEANETFPIP 69 Query: 303 -GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361 AQ+ G++P ++ ++A+ + E IDLN GCP + + +G GS ++ L Sbjct: 70 QAAQLMGSDPELMAEMARAV-ERRGAQRIDLNCGCPSNTVTGRGAGSSLLKEPDHLYKVA 128 Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 + + +++P T K+R+G + D + H + G +T+H R++ Y + WE Sbjct: 129 KSMVEAVNVPVTAKLRSG-FTDTSLFHDNLLAAQASGIKYLTLHPRTKVDGYGPPAKWEL 187 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE---- 477 I A+ PV GNGDI + +D + M K G+MIGRG++I P+IF+EIK Sbjct: 188 IAQ-AKQLLKIPVVGNGDILTVQDALNMLK-QTKCDGLMIGRGSVINPFIFHEIKSHFSA 245 Query: 478 ---QKIWDISSK--DRF-EILKKYSNYG 499 +K WD+ S+ D F E LK+ S G Sbjct: 246 QPFEKKWDVFSRYIDVFTEDLKEMSVKG 273 >UniRef50_Q251N6 Cluster: Putative uncharacterized protein; n=2; Desulfitobacterium hafniense|Rep: Putative uncharacterized protein - Desulfitobacterium hafniense (strain Y51) Length = 326 Score = 107 bits (258), Expect = 6e-22 Identities = 65/228 (28%), Positives = 112/228 (49%), Gaps = 3/228 (1%) Query: 248 YLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQIC 307 +L+P+ V + FR + G EM ++L + ++ Q+ Sbjct: 18 FLAPMAGVTDKAFRETVRSVGGLHVWTEMISDKALTYMNSRTLEMLDLSGEASPRIVQLF 77 Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367 G+ P ++ K A L E + + ID+N+GCP I K G GS ++ LP + K Sbjct: 78 GSEPEVMAKAAALAVER-DAEIIDINMGCPTPKIVKNGEGSALLQDLPLAQRIAEAVVKA 136 Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427 + +P TVKMR G ++ + + ++ G +++VHGR+RE Y +++ + I+ + Sbjct: 137 VEVPVTVKMRLGWTAERIVAPELAKRVEAVGVQMVSVHGRTREQFYAGTANRDGIKK-VK 195 Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 PV NGDIFS ++ + + A GVM+GRG+L PW+ +I Sbjct: 196 GGVSIPVIANGDIFSPQEAKTVLE-ATGCDGVMVGRGSLGNPWLIPQI 242 >UniRef50_Q31II6 Cluster: Dihydrouridine synthase; n=1; Thiomicrospira crunogena XCL-2|Rep: Dihydrouridine synthase - Thiomicrospira crunogena (strain XCL-2) Length = 320 Score = 107 bits (257), Expect = 8e-22 Identities = 70/228 (30%), Positives = 109/228 (47%), Gaps = 5/228 (2%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK-GLKQEWALVKRHETEDLFGAQIC 307 L+P+ + + +R IC+E GA EM + L+ K + ET Q+ Sbjct: 14 LAPMAGITDRVYRDICRESGASYAVSEMVASKKQLRESAKSSTRHADKTETSPRI-VQLL 72 Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367 G +P + A L Q++ D IDLN+GCP + GS +M + + + ++ Sbjct: 73 GTHPEELVDAA-LWQQSQGADIIDLNMGCPAKKVCDVAAGSALMGQPERVADIFKSLTEA 131 Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427 + +P TVK+RTG D I G IT+HGR+R ++ ++++ I+ Q Sbjct: 132 IDLPVTVKIRTGTDVDNINAVEIAKLAQELGLKAITIHGRTRADKFNGQAEYDTIKAVKQ 191 Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 A PV NGDI S ++ + K + G+MIGR A PWIF EI Sbjct: 192 -AVDIPVIANGDICSPKEAQFVLKYTGS-DGIMIGRAAQGYPWIFREI 237 >UniRef50_A4YUQ6 Cluster: Putative tRNA-dihydrouridine synthase; n=4; Rhizobiales|Rep: Putative tRNA-dihydrouridine synthase - Bradyrhizobium sp. (strain ORS278) Length = 317 Score = 107 bits (257), Expect = 8e-22 Identities = 71/226 (31%), Positives = 107/226 (47%), Gaps = 8/226 (3%) Query: 252 LTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDL--FGAQICGN 309 ++ + + PFRR+ E GA + EM + L++G W R E + Q+ G Sbjct: 1 MSGITDAPFRRLAAELGAGLVVSEMTASDDLVRG---RWISRLRCEAGGIGPHVVQLAGC 57 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369 + + + A++ + D ID+N+GCP + GS +M L T + + + Sbjct: 58 EAHWMAEGAKVAADGGA-DIIDINMGCPARHVTGGQSGSALMRDLDHALTLIEATVEAVD 116 Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429 +P T+KMR G + + + G LITVHGR+R+ Y +DW + Q A Sbjct: 117 VPVTLKMRLGWDERSLNAPELARRAEAAGVQLITVHGRTRQQFYKGEADWSAVRAVKQ-A 175 Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 PV NGDI SYED E A VMIGRGA +PW+ +I Sbjct: 176 VDLPVVVNGDITSYEDAREALD-ASGADAVMIGRGAQGQPWLPGQI 220 >UniRef50_Q0G7A4 Cluster: Nitrogen regulation protein nifr3; n=2; Aurantimonadaceae|Rep: Nitrogen regulation protein nifr3 - Fulvimarina pelagi HTCC2506 Length = 344 Score = 107 bits (256), Expect = 1e-21 Identities = 77/278 (27%), Positives = 131/278 (47%), Gaps = 13/278 (4%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N+++ +PL+ + ++PFRR+ + FGA + EM +KG +E L + + Sbjct: 18 NRVFAAPLSGISDVPFRRLSRRFGAGLVVSEMVASGEFVKG-AEEGKLRALRDGPGVHTV 76 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHR----LPALETS 360 Q+ G +P + + A+ L + D ID+N+GCP + GS +M +E + Sbjct: 77 QLAGRDPIWMEEAARRLADE-GADLIDINMGCPAKKVVGGLSGSALMREPDLAFSIVEAT 135 Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420 VR A + P ++KMR G +D I + G ++ITVHGR+R Y ++DW Sbjct: 136 VRGAG---ATPVSLKMRLGWCRDSMNAAEIAVRAEAAGVTMITVHGRTRAEFYEGTADWR 192 Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKI 480 I + + PV NGD+ + + + A VM GRG +PW + + Sbjct: 193 AI-CSVKRSVGVPVVANGDL-TEANQLSAILAASGADAVMTGRGMQGRPWFAGLLAGRVT 250 Query: 481 WD-ISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFL 517 + +S+ D + + + L H+G T GV R+ L Sbjct: 251 MERLSAIDAADFVGGHYEAMLSHYGV-TTGVRHARKHL 287 >UniRef50_A7HK00 Cluster: Dihydrouridine synthase DuS; n=4; Thermotogaceae|Rep: Dihydrouridine synthase DuS - Fervidobacterium nodosum Rt17-B1 Length = 322 Score = 107 bits (256), Expect = 1e-21 Identities = 69/231 (29%), Positives = 119/231 (51%), Gaps = 15/231 (6%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308 L+P+ V + PFR++C + GA EM +S++ +K R + +D G Q+ G Sbjct: 13 LAPMAGVTDYPFRKLCLQHGAYFAFTEMISAKSVIINVKINEIYFPRQDEKDRVGVQLFG 72 Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL 368 ++ +++ A ++QE ++DLN GCP+ + KKG GS ++ L VR +L Sbjct: 73 SDYAELSEAAAIVQEKGL--WVDLNAGCPVSKVIKKGAGSALLKDLGEFRKVVRAMRSVL 130 Query: 369 SIPFTVKMRTGVYQD--KKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426 FTVK R G +D +KI + ++ + + VHGR+ + Y+ + W+ Sbjct: 131 K-RFTVKTRIGWEKDEFEKIYNILLEE----NVDAVFVHGRTAKQMYSGKATWKIYNPGF 185 Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 P+Y +GDI++ ED ++ GV++ RG++ PWIF+EI E Sbjct: 186 -----VPLYISGDIYTKED-IKNAMEQSGATGVIVARGSIGNPWIFSEIGE 230 >UniRef50_O53835 Cluster: Probable tRNA-dihydrouridine synthase; n=35; Actinobacteria (class)|Rep: Probable tRNA-dihydrouridine synthase - Mycobacterium tuberculosis Length = 389 Score = 107 bits (256), Expect = 1e-21 Identities = 76/247 (30%), Positives = 120/247 (48%), Gaps = 15/247 (6%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADV--TCGEMALCESLLKGLKQEWALVKRHET 298 I+ + + L+P+ V N+ FR +C++ T + +CE + E V H T Sbjct: 18 IELASPVVLAPMAGVTNVAFRALCRQLEQSKVGTVSGLYVCEMVTARALIERHPVTMHMT 77 Query: 299 -----EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGM--M 351 E Q+ +P A+++ D ID+N GCP+ + K+GGG+ + Sbjct: 78 TFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHIDMNFGCPVPKVTKRGGGAALPFK 137 Query: 352 HRL--PALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNW-GASLITVHGRS 408 RL + +VR A++ IP TVK R G+ D TH +++ GA+ + +H R+ Sbjct: 138 RRLFGQIVAAAVR-ATEGTDIPVTVKFRIGI-DDAHHTHLDAGRIAEAEGAAAVALHART 195 Query: 409 REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIK 468 RY+ ++DWE I Q PV GNGDI+ D + M GV+IGRG L + Sbjct: 196 AAQRYSGTADWEQIARLKQHVRTIPVLGNGDIYDAGDALAMMS-TTGCDGVVIGRGCLGR 254 Query: 469 PWIFNEI 475 PW+F E+ Sbjct: 255 PWLFAEL 261 >UniRef50_Q0FAI7 Cluster: tRNA-dihydrouridine synthase, putative; n=1; alpha proteobacterium HTCC2255|Rep: tRNA-dihydrouridine synthase, putative - alpha proteobacterium HTCC2255 Length = 324 Score = 106 bits (255), Expect = 1e-21 Identities = 68/231 (29%), Positives = 106/231 (45%), Gaps = 5/231 (2%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308 LSPL + +LP+R + FGA + EM +++ K A + + QI G Sbjct: 13 LSPLAGITDLPYRNLVSSFGAGLVVSEMVASHEIMQKGKDARARAELGFNVEGTSVQIAG 72 Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS-VRCASKL 367 + + +++ A+L++ N ID+N+GCP + GS +M R P L + Sbjct: 73 RDAFWMSECAKLIEGN-GAKIIDINMGCPAKSVVNGASGSALM-RTPDLALKLIEAVVNA 130 Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427 + IP T+K R G + + G +IT+HGR+R Y +DW I + Sbjct: 131 VDIPVTLKTRLGWDHNDLNAADLSSSAEKIGIQMITIHGRTRCQFYKGDADWRKIREVKE 190 Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478 A PV NGDI ++ GVMIGRGA KPW+ ++I + Sbjct: 191 AVN-IPVIANGDIID-TPTAKLAMKQSKADGVMIGRGAQGKPWLLSQIASE 239 >UniRef50_Q8YAB9 Cluster: Lmo0227 protein; n=55; Bacteria|Rep: Lmo0227 protein - Listeria monocytogenes Length = 331 Score = 106 bits (254), Expect = 2e-21 Identities = 67/237 (28%), Positives = 110/237 (46%), Gaps = 3/237 (1%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETED 300 ++ N++ ++P+ + N FR KEFGA + C EM + + + ++ E E Sbjct: 7 VEIKNQVVVAPMAGISNSAFRLTVKEFGAGLVCCEMISDKGIAYRNAKTLDMLYIDEKEK 66 Query: 301 LFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS 360 QI G + + A+ + ENT D ID+N+GCP++ I K G+ + + Sbjct: 67 PLSLQIFGGEKETLVEAAKFVAENTTADIIDINMGCPVNKIIKCEAGAKWLLDPNKVYDM 126 Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420 V + P TVKMR G ++ GA+ + +HGR+R Y S++W+ Sbjct: 127 VAAVVDAVDKPVTVKMRIGWDEEHVFAIENALAAERAGAAAVAMHGRTRVQMYEGSANWD 186 Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPW-IFNEIK 476 + + P NGD+ + ED + + GVMIGR AL PW I+ +K Sbjct: 187 VLRD-VKRELKIPFMANGDVRTPEDAKRILE-HTGADGVMIGRAALGNPWMIYRTVK 241 >UniRef50_Q14SX5 Cluster: Putative dihydrouridine synthase; n=1; Ruminococcus flavefaciens|Rep: Putative dihydrouridine synthase - Ruminococcus flavefaciens Length = 332 Score = 106 bits (254), Expect = 2e-21 Identities = 71/229 (31%), Positives = 112/229 (48%), Gaps = 6/229 (2%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308 L+P+ V + +R +CK +GA EM + + ++ L E E Q+ G Sbjct: 18 LAPMAGVADRAYRLMCKRYGAAYVVSEMVSAKGICYSDRKTAELCTVTEEERPMAVQLFG 77 Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL 368 + P + + +++ + D ID+N+GCP+ + G GS +M + PAL ++ A+ Sbjct: 78 SEPDFMAEAVKIVLDYRP-DIIDINMGCPVPKVVGTGAGSALM-KDPALAAAITEAAVKA 135 Query: 369 S--IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426 + P TVK+R+G D + + G + I VHGR+R+ Y+ SD I+ Sbjct: 136 AGDTPVTVKIRSGWSSDSINAPEMARALEASGTAAIAVHGRTRDMFYSGQSDMNVIKAVK 195 Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 +A + PV GNGDI E EM VMIGRG+ P+IF EI Sbjct: 196 EAVS-VPVIGNGDITDAESCAEMYG-RTGCDLVMIGRGSYGNPFIFREI 242 >UniRef50_Q9RRP8 Cluster: NifR3 protein; n=2; Deinococcus|Rep: NifR3 protein - Deinococcus radiodurans Length = 406 Score = 105 bits (252), Expect = 3e-21 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 6/228 (2%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQE-WALVKRHETEDLFGAQIC 307 L+P+ + P R++ E GA T EM L+ G +QE +L + + E Q+ Sbjct: 96 LAPMAGYSDAPMRQLAAEQGALWTVSEMISARGLVLGSEQESLSLGRPYPGEQGRAVQLF 155 Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367 G +P ++ + IDLN+GCP+ + KGG + A E VR + Sbjct: 156 GADPDVLADAVGKAEAWFAPAAIDLNLGCPVPKVRGKGGACLLQTPEVAYEL-VRAMRQA 214 Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427 + + K+R G +++ + I + GA+++TVHGR+ RYT ++DW+ I AQ Sbjct: 215 TGLDVSAKIRLGWDENRSVE--IAQGLEAAGAAVVTVHGRTSAQRYTGNADWDAIGRVAQ 272 Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 A PV G+GD+ S E R V VMIGRGA+ PW+F I Sbjct: 273 AVR-IPVIGSGDVLSPVQARE-RMQQSGVAAVMIGRGAVGNPWMFRAI 318 >UniRef50_Q3AZ67 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=20; Cyanobacteria|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Synechococcus sp. (strain CC9902) Length = 356 Score = 105 bits (252), Expect = 3e-21 Identities = 75/235 (31%), Positives = 115/235 (48%), Gaps = 7/235 (2%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGAD-VTCGEMALCESLLKGLKQEWALVKRHETEDLF 302 ++++ SPL V + FR + + + D + EM SL G + E Sbjct: 36 HSRVLQSPLAGVTDKIFRGLVRRWSRDSLLFTEMVNATSLELG-HGYGKMDDLKAEEGPI 94 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV- 361 Q+ + P+ + A+ ++ ID+N+GCP+ I KKGGGSG++ R P L T + Sbjct: 95 AVQLFDHRPHAMAHAARRAEQAGAF-LIDINMGCPVRKIAKKGGGSGLI-RDPNLATQIL 152 Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 +SIP TVK R G T ++ N GA ++T+HGR+RE + ++W Sbjct: 153 EAVVDAVSIPVTVKTRLGWCGSSSDPITWCRQLQNAGAQMLTLHGRTREQGFKGQANWNA 212 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 I QA T PV NGDI S D + +I GVM+GRG + PW+ +I+ Sbjct: 213 IAEVKQALT-IPVIANGDINSPTDALRCLEIT-GADGVMVGRGTMGSPWLVGQIE 265 >UniRef50_Q5FTP7 Cluster: Nitrogen assimilation regulatory protein NifR3; n=3; Acetobacteraceae|Rep: Nitrogen assimilation regulatory protein NifR3 - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 371 Score = 104 bits (250), Expect = 6e-21 Identities = 72/280 (25%), Positives = 133/280 (47%), Gaps = 12/280 (4%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308 L+PL+ V +LPFR++ ++ GA + EM ++++ + + + E Q+ G Sbjct: 39 LAPLSGVTDLPFRQLARDLGAGLVVSEMIASWAMIRENENTMRMARMAERGPN-AVQLAG 97 Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLI-YKKGGGSGMMHRLPALETSVRCASKL 367 +P + + A++ + + ID+N GCP+ + + GS +M + ++ Sbjct: 98 CDPKAMAQAAKISVDGGA-NLIDINFGCPVKKVAIGQMAGSALMRDEVLAGKLLEATARA 156 Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427 +++P T+KMR G + + G L+TVHGR+R+ Y ++DW +++T Sbjct: 157 VNVPVTLKMRMGWDHNSLNAPRLAKIAEESGIRLVTVHGRTRQMFYNGTADWRFVKTVKD 216 Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE-----QKIWD 482 A + PV NGDI + D E GVMIGRG +PW ++ + + + D Sbjct: 217 AVS-LPVIVNGDINTIRDAREALH-QSQADGVMIGRGCYGRPWFTAQVAQSLRTGEDVPD 274 Query: 483 ISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLS 522 EI ++ L+H+G + G+ R+ + W S Sbjct: 275 PDLATEKEIALRHYRMMLDHFG-ERPGLRLARKH-VSWYS 312 >UniRef50_Q2RTR9 Cluster: Dihydrouridine synthase TIM-barrel protein nifR3; n=1; Rhodospirillum rubrum ATCC 11170|Rep: Dihydrouridine synthase TIM-barrel protein nifR3 - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) Length = 362 Score = 104 bits (250), Expect = 6e-21 Identities = 66/229 (28%), Positives = 109/229 (47%), Gaps = 7/229 (3%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK----GLKQEWALVKRHETEDLF 302 + L+P+ V + PFRR+ ++G ++ EM LL+ G+ F Sbjct: 14 IMLAPMAGVTDSPFRRLAHDYGCPLSWTEMVASRELLRERARGVDPRLGGGAEAGRAGPF 73 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 Q+ G +P I+ + A+ + E + ID+N+GCP+ + GGS +M LP + Sbjct: 74 AVQLAGCDPLIMAEAARRV-EGAGAELIDINMGCPVRKVVGGLGGSALMRDLPLAARILE 132 Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 +++P ++KMR G + + + G S +TVHGR+R Y +DW I Sbjct: 133 AVVGAVTLPVSLKMRLGWDDASRNAVELARLAESAGISRLTVHGRTRAQMYDGRADWPAI 192 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWI 471 +A + PV NGD+ + + E+ + GVMIGR AL PW+ Sbjct: 193 GLVKRAVS-LPVIANGDVTNLSEAREILAVT-GADGVMIGRAALGAPWL 239 >UniRef50_Q55724 Cluster: Probable tRNA-dihydrouridine synthase 1; n=15; Cyanobacteria|Rep: Probable tRNA-dihydrouridine synthase 1 - Synechocystis sp. (strain PCC 6803) Length = 355 Score = 104 bits (250), Expect = 6e-21 Identities = 68/243 (27%), Positives = 120/243 (49%), Gaps = 5/243 (2%) Query: 235 PRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVK 294 P + ++ ++++ SPL+ V +L FRR+ + + + + + L+ +++ Sbjct: 32 PLQIGSLTLHSRVLQSPLSGVTDLVFRRLVRRYAPQAMLYTEMVSATEIHHLRTLPQVME 91 Query: 295 RHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRL 354 E+ Q+ P + + AQ +D+N+GCP++ I KKGGGS ++ + Sbjct: 92 IDPRENPISIQLFDCRPDFMAEAAQKAVAQGAQS-VDINMGCPVNKITKKGGGSSLLRQP 150 Query: 355 PALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT-IVPKMSNWGASLITVHGRSREARY 413 E V+ + +P TVK R G + D +I ++ + GA ++T+HGR+R Y Sbjct: 151 AVAEAIVKTVVAAVDVPVTVKTRLG-WDDGEINIVEFAQRLQDAGAQMLTLHGRTRAQGY 209 Query: 414 TKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473 + W++I QA T PV NGDIFS E + + GVM RG+L P++ Sbjct: 210 NGRARWQWIAKVKQALT-IPVIANGDIFSVEAAIACLE-ETGADGVMCSRGSLGYPFLVG 267 Query: 474 EIK 476 EI+ Sbjct: 268 EIE 270 >UniRef50_O83945 Cluster: Probable tRNA-dihydrouridine synthase; n=2; Treponema|Rep: Probable tRNA-dihydrouridine synthase - Treponema pallidum Length = 340 Score = 104 bits (249), Expect = 8e-21 Identities = 66/240 (27%), Positives = 120/240 (50%), Gaps = 11/240 (4%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 ++ +P+ + FR I E+ A T EM E++++ L++R E + QI Sbjct: 21 VFFAPVAGYSDSAFRSIAIEWEASFTYTEMVSSEAMVRDSLNTKRLIRRASNETHYAIQI 80 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 G+NP ++ + A+L+ ++ + ID+N GCP+ I K G G+ + L V+ + Sbjct: 81 FGSNPAVMAETAKLIVDSAQPSCIDINAGCPMPKITKTGAGAALTREPTRLYEVVKAVAD 140 Query: 367 LL-----SIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITVHGRSREARYTKSSDWE 420 + IP TVK+R G +++ +T + + + GA + +H R+ Y ++W+ Sbjct: 141 AVYAQDARIPVTVKIRAG-WEEAHLTWKEAARAAVDAGAQALALHPRTCAQCYAGEANWD 199 Query: 421 YIE---TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 I CA+ PV+G+GD+ + ED M + GVM RGA+ P+IF + ++ Sbjct: 200 IIADLVQCARGWGEVPVFGSGDLHAPEDARAMLE-HTACAGVMFARGAMGNPFIFRQTRQ 258 >UniRef50_Q00XL7 Cluster: TRNA-dihydrouridine synthase; n=1; Ostreococcus tauri|Rep: TRNA-dihydrouridine synthase - Ostreococcus tauri Length = 295 Score = 103 bits (247), Expect = 1e-20 Identities = 51/118 (43%), Positives = 73/118 (61%), Gaps = 3/118 (2%) Query: 371 PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAAT 430 P TVK+R G+ T I ++ N GA+ I VHGR++E RYTKS+D++ I Sbjct: 36 PLTVKIRLGIESSSPATK-IAERLENAGAAAIIVHGRTKEQRYTKSADYDVIRQIVSERA 94 Query: 431 PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDR 488 PV GNGD+ ++ D + R G+M+GRGALIKPWIF E +E+K W+ +++DR Sbjct: 95 -IPVIGNGDVLTWYD-AQQRLDYSGCAGIMVGRGALIKPWIFKEFREKKEWEPTAEDR 150 >UniRef50_Q090Q9 Cluster: TRNA-dihydrouridine synthase B; n=2; Cystobacterineae|Rep: TRNA-dihydrouridine synthase B - Stigmatella aurantiaca DW4/3-1 Length = 369 Score = 102 bits (245), Expect = 2e-20 Identities = 65/232 (28%), Positives = 112/232 (48%), Gaps = 3/232 (1%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVK-RHETEDLFG 303 N L+P+ V PFR I ++GA + E+ + L++ ++ ++ E E + Sbjct: 43 NPYILAPMAGVSERPFRVIAFKWGAALCPTELVSAQGLMRANQRTLKYLRFSPEVERPYS 102 Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 QI G P + + A L+ + ID+N+GCP+ + K G GS +M V+ Sbjct: 103 LQIFGGEPEAMAQAA-LVGKAHGAQIIDINMGCPVKKVTKNGAGSALMCEPLRAARIVQA 161 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 ++ +P T K+R+G + + ++ + G + + +H R+R+ Y+ +DW I Sbjct: 162 IAEATGLPVTCKIRSGWDAHHRNYLQMAGELFSAGCAALAIHPRTRDQGYSGFADWSVIA 221 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 + + GNGD+ + D MR+ VMIGRGAL PWIF E+ Sbjct: 222 DLKRHFPDRTLIGNGDVKTPADARRMRE-TTGCDFVMIGRGALGNPWIFREL 272 >UniRef50_A7BE39 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 411 Score = 102 bits (245), Expect = 2e-20 Identities = 61/210 (29%), Positives = 99/210 (47%), Gaps = 11/210 (5%) Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334 EM +L++ ++ +V+ E + Q+ G NP ++ K A +L E D IDLN Sbjct: 74 EMVTSRALVEENERTLEMVRPDPAERVRSLQLYGVNPAVMAKAATMLVERDLTDHIDLNF 133 Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL---------SIPFTVKMRTGVYQDKK 385 GCP+ + KKGGG+ + + V + IP TVK+R G+ + + Sbjct: 134 GCPVPKVTKKGGGAALPWKRDLFSDLVGAVVRACDEAGERAGREIPVTVKIRIGIDSEHE 193 Query: 386 ITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYED 445 GA+ +T+H R++ Y + W+ I + PV+GNGD+F D Sbjct: 194 TATDAALNAQKLGAAALTLHARTQNQHYAGHAHWDEIAR-LKDLLDIPVFGNGDVFEAAD 252 Query: 446 YVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 + M + G+ +GRGA +PWIF +I Sbjct: 253 ALAMLE-QTGCDGISVGRGAQGRPWIFRDI 281 >UniRef50_Q607L4 Cluster: TIM-barrel protein, yjbN family; n=10; Proteobacteria|Rep: TIM-barrel protein, yjbN family - Methylococcus capsulatus Length = 327 Score = 102 bits (244), Expect = 3e-20 Identities = 68/233 (29%), Positives = 113/233 (48%), Gaps = 5/233 (2%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETE-DLF 302 ++ + L+P+ V +LPFRR+C++FGA + EM L+ ++ L + H E Sbjct: 9 SSPVILAPMAGVTDLPFRRLCRQFGAGLAVSEMISASPALQATRKS-RLRQDHRGEPGPI 67 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 QI G +P + + A+ + D ID+N+GCP + GS ++ + + Sbjct: 68 SVQIVGADPREMAEAARRTVD-LGADIIDINMGCPAKKVCNVAAGSALLRDEKLVANILE 126 Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 + + +P T+K+RTG + +I + G +TVHGR+R + ++++ I Sbjct: 127 AVVQAVPVPVTLKIRTGWDSASRNAVSIGKIAESAGIRALTVHGRTRACGFAGAAEYSTI 186 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 T + A PV NGDI S E + VMIGRGA +PW+ EI Sbjct: 187 -TEVKKAIGIPVIANGDIDS-PGKAEAVLRSTGADAVMIGRGAWGRPWLLREI 237 >UniRef50_A7CWF1 Cluster: Putative TIM-barrel protein, nifR3 family; n=1; Opitutaceae bacterium TAV2|Rep: Putative TIM-barrel protein, nifR3 family - Opitutaceae bacterium TAV2 Length = 389 Score = 101 bits (241), Expect = 7e-20 Identities = 74/234 (31%), Positives = 113/234 (48%), Gaps = 9/234 (3%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLKGLKQEWALVKRHETEDLF 302 ++ L+LSPL NLP R +E G ++ SL++ K LV+ + Sbjct: 9 SSNLFLSPLAGYTNLPMRLTVRELGGLGWATTDLVNARSLIERSKGAMKLVETAPGDQPL 68 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 Q+ G+ P + A + +E +D+N+GCP+ + GGG+ MM L VR Sbjct: 69 AIQLFGSVPEEMRDAAVICKE-LGAQSVDVNMGCPVKKVVGIGGGAAMMTELNKTAALVR 127 Query: 363 CASKLLS--IPFTVKMRTGVYQDKKITHTIVPK-MSNWGASLITVHGRSREARYTKSSDW 419 + + IP T KMR G + D IT + + +++ G + I VHGR+R ++ + + Sbjct: 128 GMVEAVGNKIPVTAKMRLG-WDDANITAPDLARVLADVGVAAIFVHGRTRAQGFSGTVNL 186 Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIF 472 I +A PV GNGD+ + E M IA T GV +GRGA PWIF Sbjct: 187 AGIRAVVEAVPGLPVIGNGDVTTPESARHM--IAETGCAGVSVGRGAFYDPWIF 238 >UniRef50_Q5ZRM0 Cluster: Nitrogen regulation protein; n=4; Legionella pneumophila|Rep: Nitrogen regulation protein - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 329 Score = 100 bits (239), Expect = 1e-19 Identities = 72/251 (28%), Positives = 117/251 (46%), Gaps = 13/251 (5%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTC-GEMALCESLLKGLKQEWALVKRHETEDLFG 303 ++L PL PFR + + C EM +L + + R TE Sbjct: 19 HRLIQGPLAGYSCAPFRDLFNIYTPPAYCVSEMCSAIDILHKHSSQSRYIYRAPTEKFLA 78 Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM---HRLPALETS 360 QI GN P+++ + A LQ + D ID+N GCP I KKG GS ++ +L A+ + Sbjct: 79 YQISGNEPHVLAEAAAKLQ-SLGADLIDINCGCPKSKIRKKGAGSALLEDPQKLIAIISR 137 Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420 VR A +SIP T+K+R Q+ + T+ ++ + GA + VHGR Y +W+ Sbjct: 138 VRAA---ISIPLTIKIR---IQNNEKDLTLAKQIEDAGAHALIVHGRRWTEDYDIPCNWQ 191 Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKI 480 I A PV NGDI + + +I+ G MI R KPW++ ++ + Sbjct: 192 QIANIKNAVN-IPVIVNGDINNIFSLRKALEIS-ACDGFMISRAGTGKPWLYRDLLNLET 249 Query: 481 WDISSKDRFEI 491 D++ ++ ++ Sbjct: 250 NDVAFDEKLKL 260 >UniRef50_A6DPY9 Cluster: Putative uncharacterized protein; n=1; Lentisphaera araneosa HTCC2155|Rep: Putative uncharacterized protein - Lentisphaera araneosa HTCC2155 Length = 330 Score = 99 bits (238), Expect = 2e-19 Identities = 80/233 (34%), Positives = 117/233 (50%), Gaps = 16/233 (6%) Query: 246 KLYLSPLTTVGNLPFR-RICKEFGADVTCGEMALCES---LLKGLKQEWALVKRHETEDL 301 KL L+P+ V + R +I + G D+ C E S ++ LK++ +VK + Sbjct: 8 KLSLAPMEGVTHPLMRHQIAQHGGLDLLCTEFIRISSHKPSMRSLKKQ--IVKSGDIP-- 63 Query: 302 FGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361 QI GNN ++ + A+L+ + D +D+N+GCP K G GS M+ + P L V Sbjct: 64 LSVQIMGNNAELMAESAKLVVD-CGADAVDVNMGCPTKRAVKGGVGSAML-KDPKLCYQV 121 Query: 362 RCASKLLSIP--FTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419 AS +P + K+R G + +K+ I+ + + GA + VH R R Y SDW Sbjct: 122 -LASMREQVPCALSAKIRAG-FDNKEGVFEILQAIVDSGADYLAVHPRRRVDHYEGHSDW 179 Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 I + + P PV GNGD+ + D V M K GVMIGRGAL PWIF Sbjct: 180 RIISALKEKS-PIPVIGNGDVRTAADAVRMFK-ETQCDGVMIGRGALSNPWIF 230 >UniRef50_Q8RFK3 Cluster: Nitrogen regulation protein NIFR3; n=3; Fusobacterium nucleatum|Rep: Nitrogen regulation protein NIFR3 - Fusobacterium nucleatum subsp. nucleatum Length = 307 Score = 99.1 bits (236), Expect = 3e-19 Identities = 70/234 (29%), Positives = 116/234 (49%), Gaps = 8/234 (3%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305 K+Y++P+ V + FR I ++F D+ EM +L + + + K + + Q Sbjct: 3 KIYIAPIAGVTDYTFRGILEDFKPDLIFTEMVSVNAL--SVLNDKTISKILKLREGNAVQ 60 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 I G + I + + EN + I+LN GCP+ I G G+ ++ ++ + Sbjct: 61 IFGEDIEKIKASVKYI-ENLGVKHINLNCGCPMKKIVNCGYGAALVKEPEKIKKILSEIK 119 Query: 366 KLLS--IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 +L+ +VK+R G Y++ + I G ITVHGR+RE Y+ +DW+YI+ Sbjct: 120 SVLNNDTKLSVKIRIG-YKEPENYIQIGKIAEELGCDHITVHGRTREQLYSGKADWKYIK 178 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 + PV GNGDIF+ ED +E + V GVM+ RG PW+ +I+E Sbjct: 179 EVKDNIS-IPVIGNGDIFTGEDALE-KIFYSNVDGVMLARGIFGNPWLIRDIRE 230 >UniRef50_Q0C0N1 Cluster: Putative tRNA-dihydrouridine synthase; n=1; Hyphomonas neptunium ATCC 15444|Rep: Putative tRNA-dihydrouridine synthase - Hyphomonas neptunium (strain ATCC 15444) Length = 345 Score = 99.1 bits (236), Expect = 3e-19 Identities = 71/234 (30%), Positives = 111/234 (47%), Gaps = 10/234 (4%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305 +++L+P++ + P RR FGA EM E L K RHE + Q Sbjct: 22 RVWLAPMSGATDAPMRRQAVHFGAPAVVSEMVAGEMLAKARADVVRRTCRHEGAGYWIVQ 81 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 + P + A L+ E +D ID+N+GCP + GS +M LP + A Sbjct: 82 LAARRPEDMLAGAVLMAE-AGVDVIDINMGCPSKQVTGGQSGSALMRDLPLAGEIIDAAL 140 Query: 366 K-LLSIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITVHGRSREARYTKSSDWEYIE 423 + P T+KMR G + D+ + + M+ + G ++TVHGR+R YT ++W + Sbjct: 141 QGAAGRPVTLKMRLG-WDDENLNAPELAVMAQDRGVQMLTVHGRTRCQFYTGGANWAAVR 199 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRK-IAPT-VKGVMIGRGALIKPWIFNEI 475 A + PV NGDI D R+ +A + GVM+GR A+ +PW+ E+ Sbjct: 200 ATVDAVS-LPVIVNGDI---SDTASAREALAQSGAYGVMLGRAAMGRPWLVGEV 249 >UniRef50_Q5CSA9 Cluster: Dus1p, tRNA dihydrouridine synthase; n=2; Cryptosporidium|Rep: Dus1p, tRNA dihydrouridine synthase - Cryptosporidium parvum Iowa II Length = 409 Score = 98.7 bits (235), Expect = 4e-19 Identities = 73/275 (26%), Positives = 132/275 (48%), Gaps = 13/275 (4%) Query: 230 LIKLLPRER-KTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEM--ALCESLLKGL 286 + KL P E K + + K L+P+ L FR ICK++G D+ M + S L+G Sbjct: 3 MTKLSPWENWKNVLKSPKTVLAPMVDGSELAFRLICKKYGCDLGYSPMYHSGLFSKLQGY 62 Query: 287 KQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG 346 ++ + E +D Q CGN+P + K ++ + + + ID+N GCP ++ + Sbjct: 63 RE--TNFQTCEEDDPMIVQFCGNDPETLVKASKFIDDKVK--GIDINFGCPQNIAKRGNY 118 Query: 347 GSGMMHRLPALETSVRCASKL-LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVH 405 G+ ++ +E + S+ L P + K+R + D + T ++ ++ + GA +I VH Sbjct: 119 GAFLLSNPDLMERIISTLSESDLKCPVSCKIRILDHHDLQPTINLIKRLESAGACMIAVH 178 Query: 406 GRSREAR--YTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGR 463 GR+ +R T ++WE ++ ++ P NG I +YED + VM Sbjct: 179 GRTMTSRGVLTGPANWEALK-ILKSRCSIPFIANGGISNYEDIQKCLNYT-GADAVMSAE 236 Query: 464 GALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNY 498 G L PW+F K + + + +F+I +Y +Y Sbjct: 237 GILENPWLFQGFKTPEAIN-NKPSQFQIALEYLDY 270 >UniRef50_Q08111 Cluster: Probable tRNA-dihydrouridine synthase; n=21; Alphaproteobacteria|Rep: Probable tRNA-dihydrouridine synthase - Rhodobacter capsulatus (Rhodopseudomonas capsulata) Length = 324 Score = 98.3 bits (234), Expect = 5e-19 Identities = 66/230 (28%), Positives = 103/230 (44%), Gaps = 8/230 (3%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDL-FGAQIC 307 L+P+ + +LPFRR+ FGA + EM +L A + T L Q+ Sbjct: 16 LAPMAGITDLPFRRMVARFGAGLVVSEMVASGEMLTAKPSVRAKAQAELTAGLPTSVQLA 75 Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367 G + + A+++ + + ID+N+GCP + G+ +M + Sbjct: 76 GREAAPMAEAAKIVAD-MGAEIIDINMGCPAKKVTGGLSGAALMRNPDHALRLIEAVVGA 134 Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427 + +P T+KMR G +D+ I + G +I +HGR+R YT ++DW I + Sbjct: 135 VDLPVTLKMRLGWDEDQLNAAEIAARAEAAGVKMIVIHGRTRMQFYTGAADWRAI-AAVR 193 Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPT--VKGVMIGRGALIKPWIFNEI 475 AA PV NGDI D R+ GVM+GRGA PW +I Sbjct: 194 AAVSVPVVANGDI---TDAASARRALDQSGAAGVMVGRGAQGAPWRLAQI 240 >UniRef50_Q89LQ7 Cluster: Nitrogen regulation protein; n=22; Alphaproteobacteria|Rep: Nitrogen regulation protein - Bradyrhizobium japonicum Length = 371 Score = 97.9 bits (233), Expect = 7e-19 Identities = 68/231 (29%), Positives = 109/231 (47%), Gaps = 8/231 (3%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDL--FGA 304 ++L+P++ V + P RR+ E GA + EM + L G + R E + Sbjct: 50 VFLAPMSGVTDSPVRRLVAELGAGLVVSEMTASDELANGHRMSRL---RCEATGIGPHVV 106 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G + + + A++ E D ID+N+GCP + GS +M L + Sbjct: 107 QLAGCEAHWMAEGARIA-EAEGADIIDINMGCPARHVTGGQSGSALMRDLDHAVGLIDAT 165 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 + +P T+KMR G + + + G L+TVHGR+R Y +DW+ I T Sbjct: 166 IAAVKVPVTLKMRLGWDDRSRNAPELARRAEAAGIKLVTVHGRTRCQFYKGEADWDAIRT 225 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 +A + P+ NGDI SYE + + + VMIGRGA +PW+ +I Sbjct: 226 VREAIS-IPLIVNGDITSYEKALAALE-SSGADAVMIGRGAQGQPWLPGQI 274 >UniRef50_Q9A7I4 Cluster: Nitrogen regulation protein Nifr3; n=2; Caulobacter|Rep: Nitrogen regulation protein Nifr3 - Caulobacter crescentus (Caulobacter vibrioides) Length = 315 Score = 97.5 bits (232), Expect = 9e-19 Identities = 72/226 (31%), Positives = 96/226 (42%), Gaps = 4/226 (1%) Query: 252 LTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNP 311 +T V +LPFR GA EM KG E L Q+ G + Sbjct: 1 MTGVSDLPFRETASALGAPYVATEMVASAEFAKGRPDVVRRAAVGEGLPLTVIQLVGRDV 60 Query: 312 YIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRCASKLLSI 370 + + A++ QE + IDLN GCP + GS +M E V A + + + Sbjct: 61 DFMAQGARMAQE-AGAEIIDLNFGCPAKEVAAGAACGSALMREPDLAEALVAAAVEAVDV 119 Query: 371 PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAAT 430 P TVKMR G D I + GA +TVHGR+R Y +DW + QA + Sbjct: 120 PVTVKMRLGWDIDCLNAPDIARRAEAAGAKAVTVHGRTRNQFYKGVADWTAVAAVKQAVS 179 Query: 431 PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 PV NGDI E + + GVMIGRG +PWI I+ Sbjct: 180 -VPVLVNGDIVDGETARQALE-QSGADGVMIGRGVYGRPWIAGAIE 223 >UniRef50_A7DPL5 Cluster: Putative TIM-barrel protein, nifR3 family; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Putative TIM-barrel protein, nifR3 family - Candidatus Nitrosopumilus maritimus SCM1 Length = 320 Score = 97.5 bits (232), Expect = 9e-19 Identities = 72/265 (27%), Positives = 126/265 (47%), Gaps = 16/265 (6%) Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGE-------MALCESLLKGLKQEWALVKR 295 ++++ +L+P+ V + R CK+ GA + E +A E L + +K ++ Sbjct: 5 FSSRAFLAPMAGVSDPALRLQCKKMGAGLVVTEFTSIHSIIAKEEQLKENMKTIQEFIEF 64 Query: 296 HETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLP 355 E E Q+ G++ Y + K A +++ D ID N+GCP I ++ G ++ + Sbjct: 65 SEQERPISVQLFGSDLYALEKAATIVEPY--FDIIDYNMGCPAPHITQQMAGGALLQEVN 122 Query: 356 ALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMS-NWGASLITVHGRSREARYT 414 + + P T+K+R+GV K + +++ + G +IT H R+ Y+ Sbjct: 123 LTQQIFETLVNAVKKPVTLKIRSGVTDASKFLFRDIAEIAEDQGIQMITFHPRTVSQGYS 182 Query: 415 KSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 S+DW+ I+ + + PV GNGDI + ED +M VMIGRGA+ P++F + Sbjct: 183 GSADWKLIKELKEISN-IPVVGNGDITTPED-AKMMLDETGCDYVMIGRGAMGNPFLFEQ 240 Query: 475 I----KEQKIWDISSKDRFEILKKY 495 I K + S KDR + Y Sbjct: 241 INDYLKTGSYKEYSFKDRLDSFFDY 265 >UniRef50_A0EG06 Cluster: Chromosome undetermined scaffold_94, whole genome shotgun sequence; n=4; Intramacronucleata|Rep: Chromosome undetermined scaffold_94, whole genome shotgun sequence - Paramecium tetraurelia Length = 360 Score = 95.9 bits (228), Expect = 3e-18 Identities = 68/237 (28%), Positives = 118/237 (49%), Gaps = 13/237 (5%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLL--KGLKQEWALVKRHETEDLFG 303 K +P+ L FR + +++G + M + K K E+ E LF Sbjct: 19 KFICAPMVDQSELAFRMLTRKYGTTLAYTPMLHSRIMTESKSYKDEF-FTTCPEDRPLF- 76 Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 AQ+CG++P ++ K A ++Q+ + D ID+N+GCP + K G+ ++ + + T V+ Sbjct: 77 AQLCGHDPQVLIKAALMIQD--QCDAIDINLGCPQGIARKGLYGAYLLEKREQVLTIVKE 134 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEY 421 + +++P T K+R +++D+K T + + G S++TVHGR++E + DW Sbjct: 135 LKQNINVPVTCKIR--MFKDRKRTLDLTKDIQEAGCSILTVHGRTKEQNKDFVGQCDWTI 192 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN-EIKE 477 I Q PV+ NG I+++ D VE V VM L P +F+ EIK+ Sbjct: 193 IAEIKQ-ILQIPVFANGGIYTWSD-VERCLQETKVDAVMSSEALLENPALFSGEIKD 247 >UniRef50_Q8ZAX7 Cluster: tRNA-dihydrouridine synthase B; n=214; Proteobacteria|Rep: tRNA-dihydrouridine synthase B - Yersinia pestis Length = 321 Score = 94.7 bits (225), Expect = 6e-18 Identities = 61/234 (26%), Positives = 106/234 (45%), Gaps = 7/234 (2%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N L +P+ + + PFR +C GA + EM + + + + + Sbjct: 10 NCLIAAPMAGITDRPFRALCHGMGAGMAVSEMLSSNPEVWRTDKSRLRMVHVDEPGIRNV 69 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 QI GN+P + A++ + ID+N+GCP + +K GS ++ ++ + Sbjct: 70 QIAGNDPDEMAAAARI-NVASGAQIIDINMGCPAKKVNRKLAGSALLQHPDLVKQILSAV 128 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 + +P T+K+RTG + + I N G +T+HGR+R + ++++ I Sbjct: 129 VNAVDVPVTLKIRTGWSPEHRNCIEIAQLAENCGIQALTIHGRTRSCLFNGEAEYDSIRA 188 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIA--PTVKGVMIGRGALIKPWIFNEIK 476 Q + PV NGDI D + R + +MIGR A +PWIF EI+ Sbjct: 189 VKQTVS-IPVIANGDI---TDPHKARAVLDYTGADALMIGRAAQGRPWIFREIQ 238 >UniRef50_Q54ES7 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 344 Score = 92.3 bits (219), Expect = 3e-17 Identities = 70/253 (27%), Positives = 117/253 (46%), Gaps = 11/253 (4%) Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309 +P+ LPFR + K++G D+T M + + + ++ ++ Q N Sbjct: 60 APMVRFSRLPFRMLVKKWGCDITYTPMIMAAEFNRSEAARDSDFTINKLDEPLIVQFGVN 119 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369 N + A+ +++ + ID+N GCP + K+G G+ ++ + V+ + + Sbjct: 120 NAEELVSAAEKVKDYCQ--GIDINCGCPQRWVMKEGFGANLLLHPERIYDMVKQINNRVP 177 Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429 IP ++K+R V D K T + + G S ITVHGR+ + + D++ I+ Sbjct: 178 IPISIKIR--VQSDLKDTIELAKRAERIGVSWITVHGRTSAMKSSHPVDYDAIKLVKDNV 235 Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRF 489 T PV+ NGD+F+ E+R+ V GVM RG L P +F + I I KD Sbjct: 236 T-LPVFANGDVFTLSQSNEIRE-KTGVNGVMSARGLLTNPALFQGYDKTPIECI--KDFI 291 Query: 490 EILKKYSNYGLEH 502 I YS YG H Sbjct: 292 NI---YSEYGGLH 301 >UniRef50_Q1QZQ6 Cluster: Dihydrouridine synthase, DuS; n=1; Chromohalobacter salexigens DSM 3043|Rep: Dihydrouridine synthase, DuS - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768) Length = 340 Score = 91.9 bits (218), Expect = 4e-17 Identities = 51/150 (34%), Positives = 78/150 (52%), Gaps = 6/150 (4%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS---IPFTVKMRTGVYQDKKI 386 +DLN GCP + + GG+ ++ + + T VR ++ L+ I T K+R G + DK + Sbjct: 99 VDLNFGCPAKTVNRHDGGASLLRQPERVHTVVRAVAEALAPLGIAVTAKIRLG-FDDKHV 157 Query: 387 THTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDY 446 + GA+ + VH R+R Y + WE+I QA PV NGDI++ EDY Sbjct: 158 ALACAEAAESGGAAHLVVHARTRREGYRPPAHWEWIGR-IQARLSIPVIANGDIWTLEDY 216 Query: 447 VEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 + R ++ VM+GRG L PW+ IK Sbjct: 217 WKARTLSGCA-DVMLGRGMLADPWLARRIK 245 >UniRef50_Q8SUV4 Cluster: Putative uncharacterized protein ECU07_1610; n=1; Encephalitozoon cuniculi|Rep: Putative uncharacterized protein ECU07_1610 - Encephalitozoon cuniculi Length = 341 Score = 91.9 bits (218), Expect = 4e-17 Identities = 69/233 (29%), Positives = 109/233 (46%), Gaps = 16/233 (6%) Query: 248 YLSPLTTVGNLP--FRRICKEFGADVTCGEMALCESLLKG----LKQEWALVKRHETEDL 301 Y + VGN +RR+ K GA++ EM C+S L+G +K W E + Sbjct: 12 YFAVAPMVGNSEEAWRRLSKRHGANIFYTEMVHCDSFLRGSRNPVKNRWYTTS--EGDRP 69 Query: 302 FGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361 QICGN+P ++ + A ++Q++ D ID+N GCP + K G G+ + V Sbjct: 70 LVVQICGNSPEVMLEAALIIQDHC--DAIDVNFGCPQKVARKGGYGAYLQENWKLTGEIV 127 Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDW 419 + S L++P K+R V+ + T + G SL+ VHGR+R+ R + W Sbjct: 128 KVLSSGLNVPVFCKIR--VFGSIEKTVEYAKMIEEAGCSLLAVHGRTRDQRGAAMGFASW 185 Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 ++I + PV NG+I ++ D + GVM+G L P IF Sbjct: 186 KHIRAIKENLR-IPVLSNGNIMTHHDVWRCLEYT-GCDGVMVGEAHLHNPLIF 236 >UniRef50_A4RVX6 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 371 Score = 91.1 bits (216), Expect = 8e-17 Identities = 55/176 (31%), Positives = 91/176 (51%), Gaps = 6/176 (3%) Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM---HRLPALET 359 GAQI G+ P+++ A+ L IDLN GCP +++ KG GS ++ + A Sbjct: 68 GAQIMGSEPWLLELAARHLATEKSAPRIDLNCGCPANVVTGKGAGSSLLRDPEYVYACVK 127 Query: 360 SVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419 +V ++ T+K+R+G Y D + + GA +++H R+R Y+ ++W Sbjct: 128 AVADGARGSGAHVTMKLRSG-YDDSSLLRENLLAAREAGARFVSLHARTRAQGYSGRANW 186 Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 E I A+ PV GNGD+ S + E+ +++ G+M+GRGA+ P IF I Sbjct: 187 EEI-AFAKDVLDIPVLGNGDVTSPQRAAELLRVS-DADGIMLGRGAVQDPLIFRRI 240 >UniRef50_A3VNG3 Cluster: Dihydrouridine synthase TIM-barrel protein; n=5; Alphaproteobacteria|Rep: Dihydrouridine synthase TIM-barrel protein - Parvularcula bermudensis HTCC2503 Length = 368 Score = 90.6 bits (215), Expect = 1e-16 Identities = 67/225 (29%), Positives = 105/225 (46%), Gaps = 7/225 (3%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA-QIC 307 L+P++ + +LPFRR GA + EM E ++ + + AL T D Q+ Sbjct: 32 LAPMSGITDLPFRRAALRAGAPLVVSEMVASEEWVRE-RPDVALRAALPTGDSLNVIQLA 90 Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367 G + + A E D ID+N+GCP + GS +M + + ++ Sbjct: 91 GREARWMREGAAKA-EALGADIIDINMGCPARKVTGLLSGSALMRDVDHALSLIKATLSG 149 Query: 368 LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQ 427 S P T+KMR G I ++ G ++ITVHGR+R+ Y ++DW + + Sbjct: 150 TSRPVTLKMRLGWDHGHLNAPEIAKGAADAGVAVITVHGRTRQQFYKGTADWRAVRATVE 209 Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWI 471 A + PV NGDI +D +A + GVMIGR A +PW+ Sbjct: 210 AVS-VPVIVNGDI--VDDVTARAALAQSGAAGVMIGRAAEGRPWL 251 >UniRef50_A4S141 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 307 Score = 90.6 bits (215), Expect = 1e-16 Identities = 62/233 (26%), Positives = 105/233 (45%), Gaps = 8/233 (3%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFG 303 N + +++P+ L FR +CK +GA + M ++ K + + Sbjct: 15 NPRYHVAPMVDQSELAFRELCKRYGATLGYTPMIHARLFVESPKYRREIFSTSTRDRPLL 74 Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 AQ C N+P I+ + A ++ D +D+N GCP + + G+ +M +E +R Sbjct: 75 AQFCANDPEILLRAATMIAPYC--DGVDINFGCPQRIAKRGNYGAFLMDDWKTVEALIRK 132 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWEY 421 + L +P T K+R VY D + T + GA ++ VHGR+RE + ++W Y Sbjct: 133 LDEELPVPVTAKIR--VYDDLETTLKYAKMVEAAGAQIVAVHGRTREQKRCADIRANWAY 190 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 I + A PV NGDI S + + A GV+ L P +F++ Sbjct: 191 IR-AIKDALKVPVLANGDIRSLAEARACLE-ATGADGVLSAEPLLSNPALFSD 241 >UniRef50_A5K1E0 Cluster: tRNA-dihydrouridine synthase, putative; n=5; Plasmodium|Rep: tRNA-dihydrouridine synthase, putative - Plasmodium vivax Length = 340 Score = 89.4 bits (212), Expect = 2e-16 Identities = 61/230 (26%), Positives = 109/230 (47%), Gaps = 7/230 (3%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQ 305 K L+P+ + L FR +C+ + +T M ++ ++ K + + E ++ AQ Sbjct: 27 KHILAPMVDLSELAFRLLCRNYNCHLTFTPMLHAKNFVEHEKYRKSYFQSCEKDEPVIAQ 86 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 CGNN II + ++ E++ +DLN+GCP + K G+ ++ + + V + Sbjct: 87 FCGNNSKIILNAIEYIK--NEVNAVDLNLGCPQQIAKKGNYGAFLLQKHDEVVNLVSDIT 144 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYT--KSSDWEYIE 423 +IP T K+R + QD + T + + + +ITVHGR++E + T K D+E I+ Sbjct: 145 NNCNIPITCKIRK-IDQDYQKTLNLCYDLQSRNVKMITVHGRTKEEKGTNIKQCDYEIIK 203 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473 + P+ NG I +ED + VM L KP+ F+ Sbjct: 204 IIKERLN-IPIIANGSIEHFEDIQKCLNYT-KADAVMCAEILLEKPYFFS 251 >UniRef50_Q9JUP6 Cluster: tRNA-dihydrouridine synthase C; n=4; Neisseria|Rep: tRNA-dihydrouridine synthase C - Neisseria meningitidis serogroup A Length = 333 Score = 89.0 bits (211), Expect = 3e-16 Identities = 52/152 (34%), Positives = 82/152 (53%), Gaps = 5/152 (3%) Query: 328 DFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS--IPFTVKMRTGVYQDKK 385 D IDLN GCP + + GG+ ++ + V+ + L IP T KMR G Y+DK Sbjct: 102 DKIDLNFGCPAPTVNRHKGGAILLKEPELIFHIVKTLRERLPAHIPLTAKMRLG-YEDKS 160 Query: 386 ITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYED 445 ++ GA +TVH R++ Y + WE+I + + PV NGD+FS +D Sbjct: 161 PALECACAIAEGGACGLTVHARTKAEGYEPPAHWEWIRK-IRDSVDIPVTANGDVFSLQD 219 Query: 446 YVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 Y+ ++ I+ VM+GRGA+I+P + +IK+ Sbjct: 220 YIGIKTIS-GCNSVMLGRGAVIRPDLARQIKQ 250 >UniRef50_O52532 Cluster: tRNA-dihydrouridine synthase B; n=6; Gammaproteobacteria|Rep: tRNA-dihydrouridine synthase B - Serratia marcescens Length = 334 Score = 89.0 bits (211), Expect = 3e-16 Identities = 58/234 (24%), Positives = 106/234 (45%), Gaps = 7/234 (2%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 N L +P+ + + PFR +C GA + EM + + + + + Sbjct: 10 NCLIAAPMAGITDRPFRTLCHAMGAGMAVSEMLSSNPEVWRTDKSRLRMVHSDEPGIRSV 69 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 QI G +P + A++ + ID+N+GCP + +K GS ++ ++ + Sbjct: 70 QIAGCDPDDMAAAARI-NVASGAQLIDINMGCPAKKVNRKLAGSALLQYPDLVKRILHAV 128 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 + +P T+K+RTG + + I + G +T+HGR+R + ++++ I Sbjct: 129 VDAVDVPVTLKIRTGWAPEHRNCVEIAQLAEDCGIQALTIHGRTRACLFNGDAEYDSIRA 188 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIA--PTVKGVMIGRGALIKPWIFNEIK 476 Q+ + P+ NGDI D + R + +MIGR A +PWIF EI+ Sbjct: 189 VKQSVS-IPIIANGDI---TDPHKARAVLDYTGADALMIGRAAQGRPWIFREIQ 238 >UniRef50_O74553 Cluster: tRNA dihydrouridine synthase Dus4; n=1; Schizosaccharomyces pombe|Rep: tRNA dihydrouridine synthase Dus4 - Schizosaccharomyces pombe (Fission yeast) Length = 326 Score = 88.6 bits (210), Expect = 4e-16 Identities = 60/228 (26%), Positives = 106/228 (46%), Gaps = 5/228 (2%) Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309 +P+ LPFR++ +++ D+ M L + L K + ++ + Q + Sbjct: 25 APMVRYSKLPFRQLVRDYNTDIVYTPMILAKEFLHP-KGRYFDFSTNDADASLILQFGVD 83 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369 +P I+ K AQL+ +D I +N GCP ++G GS ++ + VR L Sbjct: 84 DPVILEKAAQLV--GPYVDGIGINCGCPQTWAIQEGIGSALLDEPEKVHKLVRAVKSTLG 141 Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429 F +++ + +D T ++ + GA +ITVHGR+R+ R + + + I + Sbjct: 142 ESFCTEVKIRIAKDLNKTRHLMQVIEKSGADIITVHGRTRQDRSSFPVNLDAIRE-VRPC 200 Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 PV NGD+ S +E+ K T +G+M RG L P +F +E Sbjct: 201 VQIPVVANGDVKSLRKGLEIAKYTET-QGIMSARGLLENPALFAGYEE 247 >UniRef50_Q6P1R4 Cluster: tRNA-dihydrouridine synthase 1-like; n=20; Euteleostomi|Rep: tRNA-dihydrouridine synthase 1-like - Homo sapiens (Human) Length = 473 Score = 87.8 bits (208), Expect = 7e-16 Identities = 60/194 (30%), Positives = 104/194 (53%), Gaps = 12/194 (6%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRC 363 Q C N+P + + A L Q+ D IDLN+GCP +I K+G G+ + L+ + Sbjct: 79 QFCANDPEVFVQAALLAQDYC--DAIDLNLGCP-QMIAKRGHYGAFLQDEWDLLQRMILL 135 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEY 421 A + LS+P T K+R DK + + + G L+TVHGR++E + + ++ WE+ Sbjct: 136 AHEKLSVPVTCKIRVFPEIDKTVRY--AQMLEKAGCQLLTVHGRTKEQKGPLSGAASWEH 193 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIW 481 I+ + A PV+ NG+I +D VE V+GVM G L P +F E + +W Sbjct: 194 IK-AVRKAVAIPVFANGNIQCLQD-VERCLRDTGVQGVMSAEGNLHNPALF-EGRSPAVW 250 Query: 482 DISSKDRFEILKKY 495 ++ +++ +I++++ Sbjct: 251 EL-AEEYLDIVREH 263 >UniRef50_Q7UXK8 Cluster: Putative uncharacterized protein; n=3; Planctomycetaceae|Rep: Putative uncharacterized protein - Rhodopirellula baltica Length = 374 Score = 86.6 bits (205), Expect = 2e-15 Identities = 70/231 (30%), Positives = 108/231 (46%), Gaps = 10/231 (4%) Query: 252 LTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWA--LVKRHETEDLFGAQICGN 309 L+ +LP R I + A T E+ L + LL K+E + + E G Q+ G Sbjct: 45 LSGYSDLPMRVIARRHSASYTICEVMLDQFLLSLTKREKTRHFLDIADEEHPVGGQLMGA 104 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKK-GGGSGMMHRLPALETSVRCASKLL 368 P + A L E D ID+N GCP+ + + GG + A+E R + Sbjct: 105 EPEQFSAGALKLVE-AGFDVIDVNFGCPVKKVLGRCRGGFHLSQPAVAIEILRRTRDVVP 163 Query: 369 S-IPFTVKMRTGVY---QDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 IP TVKMR G+ + ++ I+ + G + +TVHGR+ RY S W +++ Sbjct: 164 DHIPVTVKMRRGMDDTPESREQFFEILDGAIDAGLAGVTVHGRTVMQRYIGPSRWAFLKE 223 Query: 425 CAQ-AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 Q + G+GD+F+ D +EM + + GV I RGA+ PWIF + Sbjct: 224 VKQHVGDRLKILGSGDLFAAVDGLEMMR-QTGIDGVTIARGAIGNPWIFQQ 273 >UniRef50_Q7UKE8 Cluster: Putative uncharacterized protein; n=2; Planctomycetaceae|Rep: Putative uncharacterized protein - Rhodopirellula baltica Length = 364 Score = 86.6 bits (205), Expect = 2e-15 Identities = 66/233 (28%), Positives = 102/233 (43%), Gaps = 14/233 (6%) Query: 250 SPLTTVGNLPFRRICKEFG-ADVTCGEMA-------LCESLLKGLKQEWALVKRHETEDL 301 +P+ N FR I ++FG A + EM L E+ + + W + E L Sbjct: 33 APMAGFTNAAFRHIVRQFGGAGLLATEMVNARGFVWLDENEAEHPDRLWGVAD--EPRPL 90 Query: 302 FGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361 QI N+P + KV + L E + +D+N GCP+ + +K + R P ++ Sbjct: 91 -AVQIWDNDPETMAKVGRRLAEEYRVSVVDINFGCPVRQVTEKAHSGSYLLREPNRMHAI 149 Query: 362 --RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419 R P T K+R G ++ + I + GA+ +TVHGR+ + ++DW Sbjct: 150 ISRLVQVCAPTPVTAKIRLGCSRENINCNEIARVVEEAGAAALTVHGRTAADMFRGNADW 209 Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 E I P+ GNGD+ S E V V VMI R L +PW+F Sbjct: 210 ERISEIKSHLRNIPLIGNGDLDSAEKVVAAFD-QYDVDAVMIARACLGRPWLF 261 >UniRef50_Q30WR3 Cluster: Dihydrouridine synthase family protein; n=3; Desulfovibrio|Rep: Dihydrouridine synthase family protein - Desulfovibrio desulfuricans (strain G20) Length = 376 Score = 86.6 bits (205), Expect = 2e-15 Identities = 63/234 (26%), Positives = 108/234 (46%), Gaps = 11/234 (4%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEM--ALCESLL---KGLKQEWALVKRHET 298 N +L+L+P+ +G++ +R++ + FG CG + +C + + + R E Sbjct: 56 NGRLFLAPMAGLGHIAYRQVLESFGG---CGLVFTGMCSARAVPTENPARSPVFSWRPEE 112 Query: 299 EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALE 358 Q+ G +P + A+ + E+ +D+N+GC + I KKG G+ ++ Sbjct: 113 LPALVCQLFGADPQDMAAAARRV-ESEGFFGVDINMGCSVAPIVKKGCGADLLRDPERAV 171 Query: 359 TSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSD 418 V + +S+P VKMRTG D + + ++ + GA + H R R T Sbjct: 172 RMVDAVRRAVSVPVFVKMRTGWSPDPEPAVNLARRLQDAGADALVFHPRVAPDRRTHRPR 231 Query: 419 WEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 +I + A PV GNGD+F D M + GV +GR A+ +PWIF Sbjct: 232 TAHI-GLVKDAVDIPVIGNGDVFDAADCAAMLE-RTGCDGVSLGRLAIARPWIF 283 >UniRef50_Q9FH91 Cluster: Gb|AAF51525.1; n=6; Magnoliophyta|Rep: Gb|AAF51525.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 423 Score = 86.6 bits (205), Expect = 2e-15 Identities = 64/232 (27%), Positives = 113/232 (48%), Gaps = 14/232 (6%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMA---LCESLLKGLKQEWALVKRHETEDLF 302 K ++P+ LPFR +C+++GA M + K QE+ K E LF Sbjct: 89 KYIVAPMVDNSELPFRLLCQKYGAQAAYTPMLHSRIFTETEKYRNQEFTTCK--EDRPLF 146 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 Q C N+P + + A+ ++ D++D+N+GCP + + G+ +M LP +++ V Sbjct: 147 -VQFCANDPDTLLEAAKRVEPYC--DYVDINLGCPQRIARRGNYGAFLMDNLPLVKSLVE 203 Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWE 420 ++ L++P + K+R ++ + + T + + G SL+ VHGR+R+ + K +DW Sbjct: 204 KLAQNLNVPVSCKIR--IFPNLEDTLKYAKMLEDAGCSLLAVHGRTRDEKDGKKFRADWS 261 Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 I+ + A PV NG++ ED K V+GV+ L P F Sbjct: 262 AIKE-VKNAMRIPVLANGNVRCIEDVDNCIK-ETGVEGVLSAETLLENPAAF 311 >UniRef50_Q9VPM1 Cluster: CG3645-PA, isoform A; n=2; Diptera|Rep: CG3645-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 505 Score = 86.2 bits (204), Expect = 2e-15 Identities = 70/240 (29%), Positives = 111/240 (46%), Gaps = 13/240 (5%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLK-QEWALVKRHETEDLFGAQIC 307 ++P+ L +R +C+ +GA++ M K ++ AL E L Q C Sbjct: 32 VAPMVDQSELAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDALQTCPEDRPLI-IQFC 90 Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRCASK 366 GN+ I A L Q++ D +D+N+GCP I K+G GS + L V Sbjct: 91 GNDAQQILDAALLAQDHC--DAVDINLGCP-QAIAKRGHYGSFLQDEWELLTEIVSTLHA 147 Query: 367 LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEYIET 424 L++P T K+R +++D + T + G L+TVHGR+RE + T ++W YI+ Sbjct: 148 KLAVPVTCKIR--IFEDLEKTIRYAKMLEAAGCQLLTVHGRTREQKGPLTGVANWNYIKN 205 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDIS 484 Q P+ NG+I + +D V V GVM G L P IF + +W ++ Sbjct: 206 VRQ-HIKIPMLANGNILALDD-VHRCLTETGVDGVMSAEGNLHNPAIFKGV-SPPVWQMA 262 >UniRef50_Q9HGN6 Cluster: tRNA dihydrouridine synthase Dus1; n=1; Schizosaccharomyces pombe|Rep: tRNA dihydrouridine synthase Dus1 - Schizosaccharomyces pombe (Fission yeast) Length = 399 Score = 86.2 bits (204), Expect = 2e-15 Identities = 68/234 (29%), Positives = 109/234 (46%), Gaps = 14/234 (5%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWA----LVKRHETEDL 301 K L+P+ LP+R + + GAD+ M S L G +++ + E Sbjct: 19 KRILAPMVDQSELPWRILARRSGADLCYSPMF--HSRLFGESEDYRNKVFSTRTIPEERP 76 Query: 302 FGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361 Q CGN+P I+ K A++ D +D+N+GCP + K GS + +E+ + Sbjct: 77 LIIQFCGNDPEIMLKAAKIAAPYC--DAVDVNLGCPQGIAKKGKYGSFLQENWNLIESII 134 Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDW 419 LSIP T K+R ++ D + T + GAS++ VHGR RE + +T +DW Sbjct: 135 TKLHTELSIPVTAKIR--IFPDPQKTLDYAKMILKAGASILAVHGRLREQKGHFTGIADW 192 Query: 420 EYIETCAQ-AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 E I+ + + ++ NG+I +D K V GV+ G+L P IF Sbjct: 193 EQIQMLRKNLPSETVLFANGNILHAQDIDRCIKYT-GVDGVLSAEGSLYNPRIF 245 >UniRef50_A6DU09 Cluster: Dihydrouridine synthase family protein; n=1; Lentisphaera araneosa HTCC2155|Rep: Dihydrouridine synthase family protein - Lentisphaera araneosa HTCC2155 Length = 334 Score = 85.8 bits (203), Expect = 3e-15 Identities = 58/218 (26%), Positives = 105/218 (48%), Gaps = 11/218 (5%) Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 AQ+ G NP ++ + D +D+N+GCP+ I K+GG S +++ + V Sbjct: 84 AQVWGKNPDKFSEAISKYVDPEVFDGVDINMGCPVAKIVKQGGCSALINTPEIAKELVLA 143 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 A +P +VK RTG+ K T + + + I +HGR+++ + + W+ I Sbjct: 144 AKAATKLPVSVKTRTGITAHK--TEEWMTHLLEVEPAAIILHGRTQKQQSEGLASWDEIA 201 Query: 424 TCAQA----ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN-EIKEQ 478 A+ P +GNGD+ S E ++ + + G MIGRG PWIFN ++ Sbjct: 202 KGARVRDRLKPHIPFWGNGDVRSIEQAHQLCQ-EHKLDGAMIGRGVFHNPWIFNTDLLGD 260 Query: 479 KIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRF 516 + + +++ +L ++++ WGS + + RRF Sbjct: 261 NV--LPPEEKIALLWRHASLYTSFWGSQ-KNFLTLRRF 295 >UniRef50_Q00RI1 Cluster: OSIGBa0125M19.5 protein; n=9; Magnoliophyta|Rep: OSIGBa0125M19.5 protein - Oryza sativa (Rice) Length = 319 Score = 84.6 bits (200), Expect = 7e-15 Identities = 68/248 (27%), Positives = 111/248 (44%), Gaps = 22/248 (8%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK-------GLKQEWALV 293 +++ +KL L+P+ VG LPFR + E+GAD+T GE + LK L L Sbjct: 1 MEYRDKLVLAPMVRVGTLPFRLLAAEYGADITYGEEIIDHKFLKCERVTNESLGTTDFLE 60 Query: 294 KRHET---------EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKK 344 + +T D Q+ ++ K AQL+ + ID+N+GCP Sbjct: 61 RGTDTVVFRTCPQERDRVVFQMGTSDAVRALKAAQLVCNDVAA--IDINMGCPKSFSLSG 118 Query: 345 GGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITV 404 G G+ ++ + + + + L T K+R + ++ T + ++ G + V Sbjct: 119 GMGAALLSKPELIHDILTTLRRNLDTTVTCKIR--LLNTRQDTVELARRVEKIGVPALAV 176 Query: 405 HGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRG 464 HGR + R + W+ I A + PV NGD+F YED+ + K A VM+ RG Sbjct: 177 HGRKVKDRPRDPAKWDEIADVVSALS-IPVIANGDVFEYEDFKRI-KDATGAASVMVARG 234 Query: 465 ALIKPWIF 472 A+ IF Sbjct: 235 AMWNASIF 242 >UniRef50_Q5LRN6 Cluster: TRNA-dihydrouridine synthase, putative; n=10; Rhodobacterales|Rep: TRNA-dihydrouridine synthase, putative - Silicibacter pomeroyi Length = 327 Score = 84.2 bits (199), Expect = 9e-15 Identities = 54/227 (23%), Positives = 97/227 (42%), Gaps = 3/227 (1%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308 L+P+ + + PFR + EFGA + EM + +++ + + Q+ G Sbjct: 16 LAPMAGITDRPFRDLVMEFGAGMVVSEMVASQEMVQAKPGVRERAELSADVENTAVQLAG 75 Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL 368 + + I + A+ + + ID+N+GCP + GS ++ + + Sbjct: 76 RDTHWIAEAARQVADR-GARVIDINMGCPAKKVTNGYSGSALLKTPDHALRLIEAVVAAV 134 Query: 369 SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQA 428 +P T+K R G + + + G ++T+HGR+R Y +DW I + Sbjct: 135 DVPVTLKTRLGWDDTLMNAPDVARRAAEAGVRMVTIHGRTRCQFYKGRADWAAI-AAVRE 193 Query: 429 ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 A P+ NGDI + GVM+GRGA +PW+ +I Sbjct: 194 AVDVPLIANGDI-TCAHTARQALDRSGADGVMVGRGAQGRPWLLAQI 239 >UniRef50_Q54XQ6 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 435 Score = 84.2 bits (199), Expect = 9e-15 Identities = 64/236 (27%), Positives = 113/236 (47%), Gaps = 14/236 (5%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLL--KGLKQE-WALVKRHETEDLF 302 K ++P+ L FR +C+++GAD+ M ++ K +++ W+ E L Sbjct: 53 KKTVAPMVDHTFLAFRMLCRKYGADMVYTPMFHSKNFATCKTYRRDYWSTCP--EDRPLV 110 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 Q CGN P + K A+ ++++ D IDLN+GCP + + GS ++ + + V+ Sbjct: 111 -VQFCGNEPEWVVKAAKYIEDHC--DAIDLNLGCPQQIARRGNYGSFLLDKPHIILPIVQ 167 Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWE 420 K + +P K+R D I + ++ G L+T+HGR++E + S ++W+ Sbjct: 168 ELHKHIKVPIFCKIRLLPNLDDTI--KLALQLQEAGCQLLTIHGRTKEQKGHNSGIANWK 225 Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 I T + + PV NG + YED ++ GVM G L P F+ +K Sbjct: 226 AIRTIREQLS-IPVIANGSVVQYED-IDRCLEETGADGVMSAEGILANPSFFSGLK 279 >UniRef50_Q8YMN5 Cluster: Transcriptional regulator; n=5; Bacteria|Rep: Transcriptional regulator - Anabaena sp. (strain PCC 7120) Length = 349 Score = 83.8 bits (198), Expect = 1e-14 Identities = 61/232 (26%), Positives = 115/232 (49%), Gaps = 8/232 (3%) Query: 249 LSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQIC 307 L+P+ V NL F ++ +G+ D E + + + + ++T AQ+ Sbjct: 29 LAPMQDVTNLWFMKVIAHYGSPDYFFTEYFRVNDTSRLNRGILSAITENDTGRPVFAQMI 88 Query: 308 GNN-PYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASK 366 G + P ++ +L N + +DLN+GCP IY+K G G++ +E + + Sbjct: 89 GESIPDLVRTAKELCGYN--IAGVDLNMGCPAPRIYRKNVGGGLLLSPAKVEQILEELRQ 146 Query: 367 LLSI-PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425 ++ P TVKMR G +++ + I+ ++ L+++HGR+ + Y + ++ I Sbjct: 147 AVNDRPLTVKMRVG-FENTDTFYEILDIVNRHNIDLLSLHGRTVKDMYHGAVKYDLIAEA 205 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 + CPV NG+I S +E+ + GVM+GR A+ PW+FN+I++ Sbjct: 206 VRRVD-CPVLANGNIHSATTALEVLERTGAA-GVMVGRWAIGNPWLFNQIRQ 255 >UniRef50_A3RPJ2 Cluster: TRNA-dihydrouridine synthase; n=2; Proteobacteria|Rep: TRNA-dihydrouridine synthase - Ralstonia solanacearum UW551 Length = 369 Score = 83.4 bits (197), Expect = 2e-14 Identities = 61/202 (30%), Positives = 98/202 (48%), Gaps = 7/202 (3%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC--ASKLLSIPFTVKMRTGVYQDKKIT 387 IDLN GCP ++ + GGG+ ++ L T V A+ +I T KMR GV D + Sbjct: 136 IDLNFGCPAKVVNRHGGGAMLLSTPELLHTIVSAVRAAVPANIAVTAKMRLGV-SDTSLA 194 Query: 388 HTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYV 447 ++ GA+ + VH R+R+ Y + W++I A A PV NG++++ D+ Sbjct: 195 IDCATALAEGGAASLVVHARTRDHGYRPPAHWDWIARIAD-AVEVPVIANGEVWTVADWE 253 Query: 448 EMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDT 507 R ++ VMIGRGA+ P++ I+ Q S+ + +L+ +Y L+ + Sbjct: 254 RCRAVS-GCDDVMIGRGAVSDPFLAQRIRGQMERTPSNAEWPLVLRYLVDY-LKMLHARI 311 Query: 508 QGVESTRRFLLEWLSFLYRYVP 529 R L WLS+L R P Sbjct: 312 AACHEHGRVKL-WLSYLKRTWP 332 >UniRef50_Q4PG83 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 527 Score = 83.0 bits (196), Expect = 2e-14 Identities = 54/177 (30%), Positives = 86/177 (48%), Gaps = 8/177 (4%) Query: 297 ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPA 356 +T+ Q C N+P + K A+++++ D +DLN+GCP + + GS +M Sbjct: 130 DTDRPLFVQFCSNDPETLLKAAKVVEDRC--DAVDLNLGCPQHIARRGHYGSYLMEDWSL 187 Query: 357 LETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSR--EARYT 414 + + + L +P T KMR VY+ + T T + GA +ITVHGR+R + T Sbjct: 188 IFSLINILHVNLKVPVTAKMR--VYESVEKTITYARLLERAGAQIITVHGRTRNMKGHLT 245 Query: 415 KSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWI 471 +DW I +A PV+ NG++ +D+ + A GVM G L P I Sbjct: 246 GLADWAKIRAVKEAVN-VPVFANGNVLYPQDFYD-ALAATGADGVMSAEGNLYNPAI 300 >UniRef50_Q4AHG7 Cluster: Dihydrouridine synthase, DuS; n=1; Chlorobium phaeobacteroides BS1|Rep: Dihydrouridine synthase, DuS - Chlorobium phaeobacteroides BS1 Length = 337 Score = 82.2 bits (194), Expect = 4e-14 Identities = 48/157 (30%), Positives = 80/157 (50%), Gaps = 2/157 (1%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389 I+ N+GCP + K GSGM+ +E+ ++ + L + +VK R G Y+D Sbjct: 93 INWNMGCPFPRVANKQRGSGMLPHPDLVESILQKITPQLPLNLSVKCRLG-YEDASEIDA 151 Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449 ++P + S +TVH R + Y+ +W I+ P NGDIFS EDY + Sbjct: 152 LIPIFNEHRISELTVHARLGKQMYSGEVNWSAIQKLLNNLK-IPFAYNGDIFSVEDYQKF 210 Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSK 486 + P + +MIGRG L P++ ++K ++ D+S + Sbjct: 211 KITFPQINTLMIGRGLLTDPFLPAKLKGLELPDLSQQ 247 >UniRef50_UPI0000D5693C Cluster: PREDICTED: similar to dihydrouridine synthase 4-like; n=3; Coelomata|Rep: PREDICTED: similar to dihydrouridine synthase 4-like - Tribolium castaneum Length = 451 Score = 81.8 bits (193), Expect = 5e-14 Identities = 58/225 (25%), Positives = 100/225 (44%), Gaps = 5/225 (2%) Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309 +P+ L FR + K + D+ M L +S K K + + Q N Sbjct: 29 APMVRYSKLQFRNLVKSYNCDLCYTPMILADSFCKSGKARANEFTTNMNDTPLITQFAAN 88 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369 Y A ++ + D +DLN GCP +G G M+ + + V+ ++ Sbjct: 89 KVYDFVGAAYMV--SPFCDGVDLNCGCPQRWAKLQGLGCIMLEKPEVIYDLVKQCRNVIP 146 Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429 PFTV ++ + +D + + I ++ + G S +TVHGR+ + + T + E + + Sbjct: 147 KPFTVSVKLRLQKDLRRSVEICRQLEHCGVSFLTVHGRTPD-QLTGEVNKEALNLIV-GS 204 Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 PV NG + S ED +E+++ KGVM+ G L P +F E Sbjct: 205 VNVPVVANGGVKSLEDCLELQE-KTNCKGVMVANGLLTNPTLFTE 248 >UniRef50_Q47C15 Cluster: Dihydrouridine synthase, DuS; n=2; Betaproteobacteria|Rep: Dihydrouridine synthase, DuS - Dechloromonas aromatica (strain RCB) Length = 319 Score = 81.8 bits (193), Expect = 5e-14 Identities = 51/183 (27%), Positives = 92/183 (50%), Gaps = 10/183 (5%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G++P+ + + A+ L +DLN GCP +++ GGS ++ P L + A Sbjct: 69 QLLGSDPHFMAENARRLVALNPAG-VDLNFGCPAPTVFRHRGGSALLGE-PELLNEITSA 126 Query: 365 SKLL---SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 + + IPFT KMR G+ D + G + + VHGR+R Y + WE+ Sbjct: 127 VRSVVPAHIPFTAKMRLGI-DDTSRAIDCAQALEAAGINELIVHGRTRSDGYRPPARWEW 185 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKI- 480 I+ + A P+ NG++++ ED+ ++A +M+GRGA+ P + ++ ++ Sbjct: 186 IDK-VRDAIHIPLIANGEVWTVEDFRNC-QLATGCADIMVGRGAVADPLLARRVRGEETG 243 Query: 481 -WD 482 WD Sbjct: 244 GWD 246 >UniRef50_Q5A4Y0 Cluster: Potential tRNA dihydrouridine synthase; n=2; Saccharomycetales|Rep: Potential tRNA dihydrouridine synthase - Candida albicans (Yeast) Length = 339 Score = 81.4 bits (192), Expect = 6e-14 Identities = 53/222 (23%), Positives = 97/222 (43%), Gaps = 3/222 (1%) Query: 251 PLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNN 310 P+ LPFR +C+ + D+ M L ++ ++++ Q+ NN Sbjct: 32 PMVRYSKLPFRELCRFYDVDIVYTPMILAREFVRNEVARSTDFTTNDSDKCVIVQVGVNN 91 Query: 311 PYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSI 370 K +++ + +D I +N GCPI ++G G+ +M + ++ A Sbjct: 92 VDDFMKFIEMI--HPFVDGIGINCGCPIKEQVREGIGAALMSDPDLVAELIKTAKDKYGD 149 Query: 371 PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAAT 430 + + +++D T V K+ G +TVHGR++ R + + + I+ + T Sbjct: 150 SICIDTKIRIHRDINQTIDFVNKVVEAGTDTLTVHGRTKNTRSSVPVNLDAIKIIRENVT 209 Query: 431 PCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 PV NGD F+ D+ ++ V GVM RG L P +F Sbjct: 210 TIPVIANGDCFTLTDFQKIVDYT-GVDGVMSARGVLANPALF 250 >UniRef50_A6W1E8 Cluster: Dihydrouridine synthase DuS; n=1; Marinomonas sp. MWYL1|Rep: Dihydrouridine synthase DuS - Marinomonas sp. MWYL1 Length = 335 Score = 81.0 bits (191), Expect = 8e-14 Identities = 56/199 (28%), Positives = 95/199 (47%), Gaps = 6/199 (3%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G+N ++ + A L ID+N GCP + GGGS ++ AL + Sbjct: 86 QLLGSNAELMAESA-LNATKAGAKHIDVNFGCPAKRVNGHGGGSVLLQTPDALYDIMSAI 144 Query: 365 SKLL--SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 L IP + K+R G ++D+ + V + G +T+HGR+++ Y + WE I Sbjct: 145 RDTLPSDIPVSAKIRLG-FEDEALLFDNVAAIEAAGVGTLTIHGRTKKDGYKPPARWEKI 203 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWD 482 QA T V NGDI + + + I + MIGRG+L P++F +I+++ Sbjct: 204 GEI-QAKTKMTVVANGDITDTKSLLRCQSITGC-QHFMIGRGSLNNPFVFQQIRKELNGQ 261 Query: 483 ISSKDRFEILKKYSNYGLE 501 S+ D + + + +Y E Sbjct: 262 ESTADTTNLNRLFISYSRE 280 >UniRef50_A1VHK2 Cluster: Dihydrouridine synthase, DuS; n=4; Desulfovibrionaceae|Rep: Dihydrouridine synthase, DuS - Desulfovibrio vulgaris subsp. vulgaris (strain DP4) Length = 449 Score = 81.0 bits (191), Expect = 8e-14 Identities = 59/232 (25%), Positives = 105/232 (45%), Gaps = 4/232 (1%) Query: 248 YLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQIC 307 +L+PL +L FR +C++ GA V C EM + L+ L+ + Q+ Sbjct: 35 WLAPLAGYSDLSFRLLCRKAGAAVCCTEMVSAKGLIYYSPGTRDLLATTPEDAPLVVQLF 94 Query: 308 GNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL 367 G +P I+ + + L E + DLN+GC + + K G G+ M+ +P R + Sbjct: 95 GCDPDIMVRAMEPLLEQ-GFRWFDLNMGCSVPKVVKTGCGAAMLRDVPQALAVARAMLRT 153 Query: 368 LSI-PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426 K R G +++ + +++ GA +T+H R ++ + W + Sbjct: 154 AGAGRVGFKFRLGWDVGQEVWADLGRALADLGAGWVTLHPRYARQGFSGEARWSTLGELV 213 Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478 +A + PV +GD+F+ D V + V VM RGAL P +F+ +E+ Sbjct: 214 RAVS-VPVIASGDLFTAADGVRCLR-ETGVASVMYARGALNDPGVFHAHRER 263 >UniRef50_Q5KP54 Cluster: TRNA dihydrouridine synthase, putative; n=1; Filobasidiella neoformans|Rep: TRNA dihydrouridine synthase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 610 Score = 80.6 bits (190), Expect = 1e-13 Identities = 53/170 (31%), Positives = 79/170 (46%), Gaps = 8/170 (4%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q C N+P I+ A+ ++ D +D+N GCP + + GS + + + Sbjct: 155 QFCANDPDILLAAAKKVEHRC--DAVDINFGCPQGIAKRGHYGSFLQDEWELIHKLISTL 212 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSRE--ARYTKSSDWEYI 422 + LS+P T K R ++ D T M GA ++T HGR+RE + T +DWEYI Sbjct: 213 HENLSVPVTAKFR--IFPDLDKTIAYARMMEAAGAQILTCHGRTREMKGQNTGLADWEYI 270 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 + A PV+ NG+I ED ++ GVM G L P IF Sbjct: 271 RE-VKKAVKVPVFANGNILYREDVDRCMEVT-GCDGVMTAEGNLSNPAIF 318 >UniRef50_Q8XYX1 Cluster: tRNA-dihydrouridine synthase C; n=26; Proteobacteria|Rep: tRNA-dihydrouridine synthase C - Ralstonia solanacearum (Pseudomonas solanacearum) Length = 326 Score = 80.6 bits (190), Expect = 1e-13 Identities = 49/152 (32%), Positives = 80/152 (52%), Gaps = 7/152 (4%) Query: 330 IDLNIGCPIDLIYKKGGGSGMM---HRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKI 386 IDLN GCP ++ + GGG+ ++ L + ++VR A I T KMR GV D + Sbjct: 93 IDLNFGCPAKVVNRHGGGAMLLATPELLHRIVSTVRAAVP-ARIAVTAKMRLGV-SDTSL 150 Query: 387 THTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDY 446 ++ GA+ + VH R+R+ Y + W++I A A PV NG++++ +D+ Sbjct: 151 AIACATALAEGGAASLVVHARTRDHGYRPPAHWDWIARIADAVR-VPVVANGEVWTVDDW 209 Query: 447 VEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478 R ++ VMIGRGA+ P++ I+ Q Sbjct: 210 ARCRAVS-GCDDVMIGRGAVSDPFLALRIRGQ 240 >UniRef50_A1SX05 Cluster: Dihydrouridine synthase, DuS; n=3; Alteromonadales|Rep: Dihydrouridine synthase, DuS - Psychromonas ingrahamii (strain 37) Length = 314 Score = 80.2 bits (189), Expect = 1e-13 Identities = 58/175 (33%), Positives = 84/175 (48%), Gaps = 8/175 (4%) Query: 305 QICGNNPYIITKVA-QLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 Q+ G NP + + A Q + + D IDLN GCP + K GG+ ++ AL V Sbjct: 68 QLLGQNPQCLAENAHQAISIGS--DGIDLNFGCPAKTVNKNKGGAVLLKSPEALYQIVTE 125 Query: 364 ASKLLSI--PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 K + + +VK+R G Y+DK + + GA + VH R++ Y + W + Sbjct: 126 VRKAVPVFQTLSVKIRLG-YEDKSLAIENAQAIQAAGADELAVHARTKAEGYRPPAHWHW 184 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 I A T PV NGDIFS +D +I + +MIGRGAL P + IK Sbjct: 185 IAKIKDAIT-IPVTANGDIFSVDDAKRCMEITGCER-LMIGRGALATPNLAQAIK 237 >UniRef50_O95620 Cluster: tRNA-dihydrouridine synthase 4-like; n=28; Eumetazoa|Rep: tRNA-dihydrouridine synthase 4-like - Homo sapiens (Human) Length = 317 Score = 80.2 bits (189), Expect = 1e-13 Identities = 59/237 (24%), Positives = 114/237 (48%), Gaps = 9/237 (3%) Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309 +P+ L FR + +++ D+ M + +K +K + ++ + Q N Sbjct: 32 APMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAAN 91 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369 + +++ A+++ + ID+N GCP +G G+ ++++ ++ V+ + Sbjct: 92 DARLLSDAARIVCPYA--NGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQVE 149 Query: 370 IP-FTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQA 428 P F+V ++ ++ D K T + K G S ITVHGR+ E R+ + ++ I+ + Sbjct: 150 TPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERH-QPVHYDSIKIIKEN 208 Query: 429 ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE---QKIWD 482 + PV NGDI S ++ + +I T GVM+ RG L P +F +E + IWD Sbjct: 209 MS-IPVIANGDIRSLKEAENVWRITGT-DGVMVARGLLANPAMFAGYEETPLKCIWD 263 >UniRef50_Q9VY45 Cluster: CG1434-PA; n=6; Endopterygota|Rep: CG1434-PA - Drosophila melanogaster (Fruit fly) Length = 473 Score = 79.8 bits (188), Expect = 2e-13 Identities = 71/256 (27%), Positives = 117/256 (45%), Gaps = 25/256 (9%) Query: 236 RERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQ------- 288 + R+ +D+ NKL L+P+ VG LP R + E GAD+ E + L+K +++ Sbjct: 15 KTRQRLDYRNKLILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLIKSIRRPNPALGT 74 Query: 289 -------EWALVKR---HETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPI 338 + +V R ET L Q+ ++ V +LLQ ++ +D+N+GCP Sbjct: 75 VDFVDPSDGTIVFRTCAQETSRLV-LQMGTSDAGRALAVGKLLQR--DISGLDINMGCPK 131 Query: 339 DLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWG 398 + K G G+ ++ +R L IP T K+R + D + T +V K++ G Sbjct: 132 EFSIKGGMGAALLADPDKAAHILRTLCSGLDIPVTCKIR--ILPDVEGTIDLVQKLAATG 189 Query: 399 ASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPT--V 456 + I +H R+R+ R + E + AQ A P+ NG + Y ++RK Sbjct: 190 IAAIGIHARTRDERPQHPAHPEVLRAVAQ-AVDIPIIANGGSKNMHCYDDLRKFQMECGA 248 Query: 457 KGVMIGRGALIKPWIF 472 VM+ R A I IF Sbjct: 249 DSVMVARAAQINVSIF 264 >UniRef50_Q8A2H9 Cluster: Putative nifR3 family TIM-barrel enzyme with dihydrouridine synthase domain; n=6; Bacteroidales|Rep: Putative nifR3 family TIM-barrel enzyme with dihydrouridine synthase domain - Bacteroides thetaiotaomicron Length = 314 Score = 79.4 bits (187), Expect = 2e-13 Identities = 53/190 (27%), Positives = 92/190 (48%), Gaps = 5/190 (2%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389 +D+N+GCP L+ K+ GSG++ ++ + ++ I F+VKMR G Q + Sbjct: 91 VDINLGCPFPLLAKRHNGSGILPYPEEVKALLSIVTRYPQISFSVKMRLGWEQPDECL-A 149 Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449 + P +++ IT+H R + Y D + + P+ NGDI + ED + Sbjct: 150 LAPILNDLPLRQITMHPRLGKQGYKGEVDLQGFSAFREVC-QLPLVYNGDIHNLEDIQRI 208 Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIKEQK-IWDISSKDRFEILKK--YSNYGLEHWGSD 506 P++ G+MIGRG L P + E KE + + +DR + + K Y+NY + G + Sbjct: 209 STQFPSLAGIMIGRGLLANPALALEYKENRTLAPDEMRDRLKSMHKSVYNNYDVLLEGGE 268 Query: 507 TQGVESTRRF 516 Q + + F Sbjct: 269 GQLLTKMKTF 278 >UniRef50_A7AQM0 Cluster: Dihydrouridine synthase, putative; n=1; Babesia bovis|Rep: Dihydrouridine synthase, putative - Babesia bovis Length = 355 Score = 79.4 bits (187), Expect = 2e-13 Identities = 62/229 (27%), Positives = 103/229 (44%), Gaps = 8/229 (3%) Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309 +P+ LPFR +C+ + D+T M ++ K + + + AQ+CG+ Sbjct: 17 APMVNQSELPFRLLCRRYNVDLTYTPMLHGRIFVENEKYRAVHFQTSDDDRPLIAQVCGD 76 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS-VRCASKLL 368 + IT+ A+LL+ + +DLN+GCP I K G + P L T V ++ + Sbjct: 77 DAGTITQAARLLKGHVSA--VDLNLGCP-QAIAKDGHYGSFLLDEPDLVTGIVSRVTREV 133 Query: 369 SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTK--SSDWEYIETCA 426 I T K+R + T + + G +TVHGR R + T ++DW+ I Sbjct: 134 GIAVTCKIRKVDKDSLQSTLNLCYSLEQSGCKALTVHGRHRSEKGTNVGAADWDAIR-II 192 Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 ++ PV NG I ++ D VE VM L +P++F+ I Sbjct: 193 KSRLRIPVIANGGIETFAD-VERCLSYTGADAVMSSESLLERPYLFSGI 240 >UniRef50_A3JG66 Cluster: Putative uncharacterized protein; n=3; Gammaproteobacteria|Rep: Putative uncharacterized protein - Marinobacter sp. ELB17 Length = 335 Score = 78.6 bits (185), Expect = 4e-13 Identities = 64/227 (28%), Positives = 107/227 (47%), Gaps = 17/227 (7%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G++P+++ + E +D+N GCP + K GG +M R P L + A Sbjct: 68 QLLGSDPHMMARHGAKAAELGATQ-VDINFGCPAKTVNKHKGGCVLM-REPELMHEITAA 125 Query: 365 SKLL---SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 + I T KMR G Y D+ + + GA I +H RS+ Y + WE Sbjct: 126 VRQAVPADILVTAKMRLG-YDDRSMGVACAQALDAAGAGEIVIHARSKTDGYKPPAYWEE 184 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE---- 477 I A+ A V NGDIF+ DY R+++ VMIGRG + +P + +I+ Sbjct: 185 IAK-AREAVKAKVIANGDIFTVADYWRCREVS-GCDDVMIGRGLVARPDLARQIRASQRG 242 Query: 478 QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFL 524 + I ++ + ++++Y Y L+ W D T R + +W+++L Sbjct: 243 ESIELMTWPEALALVQEY-GYALQGWLEDKY---VTGR-IKQWMNYL 284 >UniRef50_Q9XVN8 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 527 Score = 78.6 bits (185), Expect = 4e-13 Identities = 73/281 (25%), Positives = 128/281 (45%), Gaps = 21/281 (7%) Query: 226 TDEDLIKLLPRERKTIDWNNKL--YLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLL 283 +DE + K L ++T++ N ++ L+P+ L FR +++GA +T M + Sbjct: 53 SDETIEKNLRFWKETLE-NQRITKVLAPMVDQSELAFRMFTRKYGAQLTFTPMIHAHLFV 111 Query: 284 KG---LKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDL 340 + ALVK Q C N +L+++ D +DLN+GCP + Sbjct: 112 NDGTYRRNSLALVKADRP---LVVQFCANKVDTFLAACRLVED--VCDGVDLNLGCP-QM 165 Query: 341 IYKKGG-GSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGA 399 + K+G GS + + + V +P + K+R V D++ T ++ + GA Sbjct: 166 VAKRGRYGSWLQDEVDLICEMVSAVRDYCRLPISCKIR--VRDDRQQTVEYAKRLVDAGA 223 Query: 400 SLITVHGRSREAR--YTKSSDWEYIETCAQA-ATPCPVYGNGDIFSYEDYVEMRKIAPTV 456 +++TVHGR+R+ + T +DW I +A + PV NG+I + VE A Sbjct: 224 TMLTVHGRTRDMKGAETGLADWSRIRDVVEAVGSRVPVMANGNI-QFPGDVERCMQATGA 282 Query: 457 KGVMIGRGALIKPWIFNEIKEQ-KIWDISSKDRFEILKKYS 496 +M G L P IF++ W I++ + E KK++ Sbjct: 283 VAIMSAEGLLYNPLIFDDANAHVDTWKIAA-EYLEYAKKFN 322 >UniRef50_P53759 Cluster: tRNA-dihydrouridine synthase 1; n=11; Saccharomycetales|Rep: tRNA-dihydrouridine synthase 1 - Saccharomyces cerevisiae (Baker's yeast) Length = 423 Score = 78.6 bits (185), Expect = 4e-13 Identities = 61/232 (26%), Positives = 104/232 (44%), Gaps = 13/232 (5%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMA---LCESLLKGLKQEWALVKRHETEDLFGAQ 305 ++P+ L +R + + +GA + M L + K + W+ + + Q Sbjct: 33 VAPMVDQSELAWRILSRRYGATLAYTPMLHAKLFATSKKYREDNWSSLDGSSVDRPLVVQ 92 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 C N+P + A+L+++ + D +DLN+GCP + K GS +M + + Sbjct: 93 FCANDPEYLLAAAKLVED--KCDAVDLNLGCPQGIAKKGHYGSFLMEEWDLIHNLINTLH 150 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWEYIE 423 K L +P T K+R ++ D + + + + GA +TVHGR RE + K+ ++WE I+ Sbjct: 151 KNLKVPVTAKIR--IFDDCEKSLNYAKMVLDAGAQFLTVHGRVREQKGQKTGLANWETIK 208 Query: 424 TCAQAATPCPV-YGNGDIFSYEDYVE-MRKIAPTVKGVMIGRGALIKPWIFN 473 V + NG+I ED M I VM G L P +FN Sbjct: 209 YLRDNLPKETVFFANGNILYPEDISRCMEHIG--ADAVMSAEGNLYNPGVFN 258 >UniRef50_A6GHV6 Cluster: Dihydrouridine synthase family protein; n=1; Plesiocystis pacifica SIR-1|Rep: Dihydrouridine synthase family protein - Plesiocystis pacifica SIR-1 Length = 321 Score = 78.2 bits (184), Expect = 6e-13 Identities = 56/171 (32%), Positives = 82/171 (47%), Gaps = 8/171 (4%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMH---RLPALETSV 361 Q+ G P+ + + A+ IDLN GCP + GG+ ++ R+ A+ +V Sbjct: 65 QLLGGEPHWMARAAETAVA-LGAPGIDLNFGCPAKTVNSSDGGATLLKDPCRVEAVTRAV 123 Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 R A +P TVK+R G ++D I GAS +T+HGR+R Y D+E Sbjct: 124 RAAVPA-ELPVTVKIRVG-WEDPSPVVEIARAAEAGGASWLTIHGRTRRQLYKPPVDYEA 181 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 I AQAA V NGD+F E + + MIGRGA+ +P +F Sbjct: 182 IGR-AQAAVSMAVVANGDLFGVPSLFEAAQRSGCT-AFMIGRGAMGRPELF 230 >UniRef50_Q884C6 Cluster: tRNA-dihydrouridine synthase C; n=8; Proteobacteria|Rep: tRNA-dihydrouridine synthase C - Pseudomonas syringae pv. tomato Length = 317 Score = 78.2 bits (184), Expect = 6e-13 Identities = 51/173 (29%), Positives = 85/173 (49%), Gaps = 6/173 (3%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G++P + + A E +DLN GCP + + GG+ ++ L T V Sbjct: 68 QLLGSDPVCLAENAAFACE-LGAPVLDLNFGCPAKTVNRSRGGAILLKEPELLHTIVSQV 126 Query: 365 SKLL--SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 + + IP T KMR G Y++ +++ GA+ I VH R++ Y + WE+I Sbjct: 127 RRAVPKDIPVTAKMRLG-YENTDGALDCARALADGGAAQIVVHARTKVDGYKPPAHWEWI 185 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 Q PV NG+I++ ED+ R+I + +MIGRG + +P + +I Sbjct: 186 AR-IQEVVKVPVVANGEIWTVEDWRRCREIC-GARDIMIGRGLVARPDLARQI 236 >UniRef50_Q7RX85 Cluster: Putative uncharacterized protein NCU00065.1; n=3; Pezizomycotina|Rep: Putative uncharacterized protein NCU00065.1 - Neurospora crassa Length = 629 Score = 77.4 bits (182), Expect = 1e-12 Identities = 53/171 (30%), Positives = 79/171 (46%), Gaps = 8/171 (4%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q C N+P + A+L+ D +DLN+GCP + + GS + + + Sbjct: 140 QFCANDPAYLLSAAKLVAPYC--DAVDLNLGCPQGIAKRGQYGSFLQENQELIFELINTL 197 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEYI 422 K L IP T K+R + K+ T + GAS++TVHGR RE + T +DWEYI Sbjct: 198 HKELDIPVTAKIR--ILDTKEATLKYAQNVLRAGASILTVHGRRREQKGHQTGLADWEYI 255 Query: 423 ETCAQ-AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 + ++ NG+I + D +E A GVM G L P +F Sbjct: 256 RYLRENLPKETVIFANGNILQHAD-LEKCLAATGADGVMSAEGNLSDPGLF 305 >UniRef50_Q06063 Cluster: tRNA-dihydrouridine synthase 4; n=10; Saccharomycetales|Rep: tRNA-dihydrouridine synthase 4 - Saccharomyces cerevisiae (Baker's yeast) Length = 367 Score = 77.4 bits (182), Expect = 1e-12 Identities = 52/224 (23%), Positives = 97/224 (43%), Gaps = 5/224 (2%) Query: 251 PLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNN 310 P+ LPFR++C+E+ D+ M L ++ + + + + Q+ NN Sbjct: 45 PMVRYSKLPFRQLCREYNVDIVYSPMILAREYVRNEHARISDLSTNNEDTPLIVQVGVNN 104 Query: 311 PYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSI 370 + K +++ D I +N GCPI ++G G +++ L + V Sbjct: 105 VADLLKFVEMVAPYC--DGIGINCGCPIKEQIREGIGCALIYNSDLLCSMVHAVKDKYGD 162 Query: 371 PFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAAT 430 ++ + +++ T + K+ + G IT+HGR+R R ++ ++ + I+ + + Sbjct: 163 KLRIETKIRIHEALDETVELCRKLCDAGVDWITIHGRTRRTRSSQPANLDAIKYIIENIS 222 Query: 431 P--CPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 PV NGD F D + K GVM RG L P +F Sbjct: 223 DKNVPVIANGDCFKLSDLERITKYT-GAHGVMAVRGLLSNPALF 265 >UniRef50_Q6MNE9 Cluster: Nitrogen regulation protein nifR3; n=1; Bdellovibrio bacteriovorus|Rep: Nitrogen regulation protein nifR3 - Bdellovibrio bacteriovorus Length = 352 Score = 77.0 bits (181), Expect = 1e-12 Identities = 52/175 (29%), Positives = 83/175 (47%), Gaps = 4/175 (2%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 QI GN I + + L E + ID+N+GCP+ K G +M VR Sbjct: 80 QILGNEEDAIAESVKRLVE-WGAEAIDINMGCPVQKALKHNYGVALMGDPAYAAEVVRMT 138 Query: 365 SKLLSIPFTVKMR-TGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 K ++P +VK+R G ++ T V + GA+ + +H R+ + ++DWE I+ Sbjct: 139 VKNSTVPVSVKLRAVGSTKEFDELLTFVSGLRQSGAAWVCLHPRTAAQKRRGNADWEQIK 198 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478 A PV GNGD+ +Y+D + M K M GRG +PW+ ++ E+ Sbjct: 199 Q-LHKAVDFPVIGNGDVQTYDDAINMLK-ETGCDMAMAGRGLAARPWMMWQLGEE 251 >UniRef50_A4E892 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 317 Score = 76.2 bits (179), Expect = 2e-12 Identities = 49/148 (33%), Positives = 73/148 (49%), Gaps = 4/148 (2%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389 ++LN+GCP + KG GSG + L LE + + +P +VK R G+ D + Sbjct: 89 VNLNLGCPSGTVVAKGKGSGFLRNLDELEAFLSDVCERSPLPVSVKTRLGLENDDEY-ER 147 Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWE-YIETCAQAATPCPVYGNGDIFSYEDYVE 448 ++ + + VH R ++ RYT E Y ET +A P PV NGDIF ED Sbjct: 148 VLDLYCRMPLAELIVHPRVQKDRYTGLPRKEFYGETLERA--PFPVAYNGDIFDLEDMDA 205 Query: 449 MRKIAPTVKGVMIGRGALIKPWIFNEIK 476 + + P + VM+GRG L P + +K Sbjct: 206 LVEAYPGTRHVMLGRGLLANPALARMVK 233 >UniRef50_Q6AKJ6 Cluster: Putative uncharacterized protein; n=1; Desulfotalea psychrophila|Rep: Putative uncharacterized protein - Desulfotalea psychrophila Length = 354 Score = 75.8 bits (178), Expect = 3e-12 Identities = 38/151 (25%), Positives = 71/151 (47%), Gaps = 2/151 (1%) Query: 328 DFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKIT 387 D +D+N+GCP + + G G+ + + V A + + + K+R G + Sbjct: 125 DGVDINLGCPAPSVRRGGAGAALAEDWDRVRDIVSSARRHTDLTLSAKIRVGHVGKEAHL 184 Query: 388 HTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYV 447 + G L+ VH R ++ + W+ + + P++ NG IFS +D Sbjct: 185 LDFCKMLEAEGVDLLAVHARYHGEKFCRKPRWQLLAPICEQLD-IPIFANGGIFSVDDAR 243 Query: 448 EMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478 +++ G+M+GRGA+ +PW+FNEI + Sbjct: 244 RCLELSGAA-GLMLGRGAVERPWLFNEIARE 273 >UniRef50_Q9XWJ9 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 436 Score = 75.8 bits (178), Expect = 3e-12 Identities = 68/250 (27%), Positives = 116/250 (46%), Gaps = 28/250 (11%) Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLK---QEWALVKRHETE 299 + NK L+P+ G P R +C ++GAD+ E + + L++ + + + + Sbjct: 5 YRNKKILAPMVRAGRTPLRLLCLKYGADLCYTEEIVDKKLIEATRVVNEALGTIDYRNGD 64 Query: 300 DLF--------GA---QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGS 348 D+ G QI N+ K+AQ++ + ++ ID+N+GCP G G+ Sbjct: 65 DIILRLAPEEKGRCILQIGTNSGEKAAKIAQIVGD--DVAGIDVNMGCPKPFSIHCGMGA 122 Query: 349 GMM---HRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVH 405 ++ ++ + TS++ A+K +P T K+R V D + T +V ++ S + VH Sbjct: 123 ALLTQTEKIVDILTSLKSAAK---VPVTCKIR--VLDDPEDTLKLVQEIEKCRVSALGVH 177 Query: 406 GRSREARYTKSSDWEYIETCAQAATPCPVYGNG---DIFSYEDYVEMRKIAPTVKGVMIG 462 GR R+ R + I AQA PV NG +I Y D+ + + + T MI Sbjct: 178 GRRRDERQPDKCRIDEIRDVAQAVQSIPVISNGLSDEIEQYSDFEKYQLLTET-SSTMIA 236 Query: 463 RGALIKPWIF 472 R AL P IF Sbjct: 237 RKALSTPSIF 246 >UniRef50_Q1JWD3 Cluster: Dihydrouridine synthase, DuS; n=1; Desulfuromonas acetoxidans DSM 684|Rep: Dihydrouridine synthase, DuS - Desulfuromonas acetoxidans DSM 684 Length = 320 Score = 75.4 bits (177), Expect = 4e-12 Identities = 51/185 (27%), Positives = 86/185 (46%), Gaps = 9/185 (4%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G+ + + AQ++ + ++LN+GCP G M+ + +R Sbjct: 74 QLIGHRSESLAEAAQIVADLGGAH-VNLNMGCPFGRTTTGKTGGAMLQEPEKIGDCLRAI 132 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 +VK+R G Y D + ++P +G I +H R+ +Y +D + Sbjct: 133 RAAFHGSVSVKVRAG-YDDPEQIFDLLPVFEKYGVDFIVLHPRTVVQKYADDAD-HAVTA 190 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTV--KGVMIGRGALIKPWIFNEIKEQKIW- 481 AAT PV NGD+FS E R++A G+M+GRGA+ PW+F I+ + + Sbjct: 191 RVVAATALPVIANGDLFSEE---RARQVAEQTGAAGLMLGRGAIADPWLFQRIRGRGVEP 247 Query: 482 DISSK 486 DIS + Sbjct: 248 DISQR 252 >UniRef50_A6PMB8 Cluster: Dihydrouridine synthase, DuS; n=1; Victivallis vadensis ATCC BAA-548|Rep: Dihydrouridine synthase, DuS - Victivallis vadensis ATCC BAA-548 Length = 304 Score = 75.4 bits (177), Expect = 4e-12 Identities = 57/176 (32%), Positives = 82/176 (46%), Gaps = 6/176 (3%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ GN P +I A E I+LN GCP + G G G + L + T+V Sbjct: 68 QLMGNRPEVIAAAAARFMELGAAG-INLNFGCPSRQVTSGGAGGGALRDLAGMVTTVETV 126 Query: 365 SKLL-SIPFTVKMRTGVYQDKKITHTIVPKMSNWG-ASLITVHGRS-REARYTKSSDWEY 421 K + + P +VK+RTG ++ I+P ++ G S +H R+ RE S E Sbjct: 127 KKAIPASPLSVKLRTG-WESPDEMQRILPALAETGCVSAFFLHFRTVREQYRPVSGREER 185 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 E + A P PV NGDI S +D E+ + GVM RG L P + N I++ Sbjct: 186 FEAGLRLAAPVPVVLNGDIDSPDDASELLE-RTGAAGVMCARGWLRDPLLLNRIRQ 240 >UniRef50_Q127F8 Cluster: Dihydrouridine synthase, DuS; n=3; Proteobacteria|Rep: Dihydrouridine synthase, DuS - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 344 Score = 74.9 bits (176), Expect = 5e-12 Identities = 55/176 (31%), Positives = 88/176 (50%), Gaps = 8/176 (4%) Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM---HRLPALETS 360 AQ+ G++P + + A L IDLN GCP ++ + GGG+ ++ L A+ ++ Sbjct: 73 AQLLGSDPACMAENAARLATLGPAG-IDLNFGCPAAVVNRHGGGASLLKEPETLLAIVSA 131 Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420 VR A +P + KMR G D + + ++ GA + VH R++ Y + WE Sbjct: 132 VRRAVP-AGMPVSAKMRLGYNDDSRAVECAL-AIAEGGAGELVVHARTKAQAYKPPAYWE 189 Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 I +AA PV NG+I++ +D R+ A +MIGRGA+ P + IK Sbjct: 190 RIAD-IRAAVQIPVVANGEIWTVDDARRCRE-ASGCSMLMIGRGAVADPGLGLAIK 243 >UniRef50_UPI00015B403F Cluster: PREDICTED: similar to MGC79829 protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to MGC79829 protein - Nasonia vitripennis Length = 346 Score = 74.5 bits (175), Expect = 7e-12 Identities = 52/231 (22%), Positives = 103/231 (44%), Gaps = 5/231 (2%) Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309 +P+ LPFR + +++ D+ M L +S ++ K + +E + Q Sbjct: 19 APMVRYSKLPFRTLVRKYDCDICFTPMILADSFVQSSKARDSEFSTNEGDSPLIVQFAAK 78 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369 + +++ + + +DLN GCP K G G+ ++ + ++ V + Sbjct: 79 EVDDFVEATEMVAPYS--NGVDLNCGCPQRWALKDGYGADLLTKPQLVKELVSNVRNRIP 136 Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429 PFTV ++ + +D K T + + G S +TVH R+ + R + D + ++ ++ Sbjct: 137 KPFTVSVKIRILKDIKKTIEFSRAIEHAGVSFLTVHARTPDMR-NEPIDLDSLK-LVRSC 194 Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKI 480 P+ NG++ S+ED + + GVM+ G L P IF+ K + Sbjct: 195 VHLPMIANGNVRSFEDAKTLYE-ESKCNGVMVAGGILTNPAIFSGYKNTPV 244 >UniRef50_A7T8A1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 137 Score = 74.5 bits (175), Expect = 7e-12 Identities = 32/63 (50%), Positives = 47/63 (74%), Gaps = 4/63 (6%) Query: 364 ASKLLSIPFTVKMRTGVYQDKKIT---HTIVPKMSNWGASLITVHGRSREARYTKSSDWE 420 A +++ IP TVK+R G++ DKK T H +V + +WG ++T+HGRSRE RYTKS+DW+ Sbjct: 53 AYQVIDIPLTVKIRAGIH-DKKYTWNAHKLVGNLRDWGTDMVTIHGRSREQRYTKSADWD 111 Query: 421 YIE 423 YI+ Sbjct: 112 YIK 114 >UniRef50_Q5HJT5 Cluster: Probable tRNA-dihydrouridine synthase; n=41; Bacilli|Rep: Probable tRNA-dihydrouridine synthase - Staphylococcus aureus (strain COL) Length = 328 Score = 74.5 bits (175), Expect = 7e-12 Identities = 75/279 (26%), Positives = 130/279 (46%), Gaps = 23/279 (8%) Query: 249 LSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLL--KGLKQEWALVKRHETEDLFGAQ 305 L+P+ V ++ FR + E DV E ES +G+ + E E A Sbjct: 16 LAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEQPMVAH 75 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 I G+ P + + L + IDLN+GCP+ + KKG GSG++ R P + + A+ Sbjct: 76 IWGDKPEQFRETSIQLAK-MGFKGIDLNMGCPVANVAKKGKGSGLILR-PDVAAEIIQAT 133 Query: 366 KLLSIPFTVKMRTGVYQDKK----ITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 K +P +VK R G Y+ + + H ++N +++H R+R+ + WE Sbjct: 134 KAGGLPVSVKTRLGYYEIDEWKDWLKHVFEQDIAN-----LSIHLRTRKEMSKVDAHWEL 188 Query: 422 IETCA----QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 IE + A + NGDI + +E+ + + GVMIGRG P+ F KE Sbjct: 189 IEAIKNLRDEIAPNTLLTINGDIPDRKTGLELAE-KYGIDGVMIGRGIFHNPFAFE--KE 245 Query: 478 QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRF 516 + + +SK+ ++L+ + + ++ + + +S RRF Sbjct: 246 PR--EHTSKELLDLLRLHLSLFNKYEKDEIRQFKSLRRF 282 >UniRef50_Q9VJ06 Cluster: CG10495-PA; n=2; Sophophora|Rep: CG10495-PA - Drosophila melanogaster (Fruit fly) Length = 396 Score = 73.7 bits (173), Expect = 1e-11 Identities = 59/227 (25%), Positives = 100/227 (44%), Gaps = 6/227 (2%) Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309 +P+ L FRR+ + G + M + +S+ K + AQ Sbjct: 28 APMVRYSKLEFRRLVRLNGVQLAFTPMMISDSINNSEKARQNEFSTGADDQPLIAQFAAK 87 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369 +P AQL+ +D IDLN GCP KG G GM+ + + V+ + L Sbjct: 88 DPTEFVTSAQLIYPY--VDGIDLNCGCPQSWAMAKGYGCGMLRQPELVHQVVQEVRRTLP 145 Query: 370 IPF--TVKMR-TGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCA 426 F +VKMR G + + T + ++ + G + +T+HGR+ +++K + + Sbjct: 146 GDFSVSVKMRLLGGEESLQRTIDLARQLESAGVTFLTLHGRTPAQKHSKDTLDIPAMSQV 205 Query: 427 QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473 + + P+ NG++ SY D +M + GVM RG L P +FN Sbjct: 206 RQSLQIPLIVNGNVESYRDACDMHE-QTGAAGVMAARGLLANPALFN 251 >UniRef50_Q6AJ40 Cluster: Putative uncharacterized protein; n=1; Desulfotalea psychrophila|Rep: Putative uncharacterized protein - Desulfotalea psychrophila Length = 318 Score = 73.3 bits (172), Expect = 2e-11 Identities = 43/147 (29%), Positives = 74/147 (50%), Gaps = 2/147 (1%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389 I+ N+GCP ++ KK GSGM+ + + + + ++K R G Y + T Sbjct: 92 INWNLGCPAPMVAKKKRGSGMLAHPDLIVEFLEEVLPQIPVKLSIKTRLG-YSNTAQTKE 150 Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449 ++P++ + + I +H R + Y ++D + C Q + Y NGDI + E + E+ Sbjct: 151 LLPRLDQFPLTEIIIHARLGKQMYKGTTDPDTFAECLQLSQHRIAY-NGDITTLEHFHEL 209 Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIK 476 + P V+ MIGRGAL P++ IK Sbjct: 210 QTRFPQVEHWMIGRGALADPFLAERIK 236 >UniRef50_Q9NX74 Cluster: tRNA-dihydrouridine synthase 2-like; n=27; Eumetazoa|Rep: tRNA-dihydrouridine synthase 2-like - Homo sapiens (Human) Length = 493 Score = 73.3 bits (172), Expect = 2e-11 Identities = 75/281 (26%), Positives = 127/281 (45%), Gaps = 37/281 (13%) Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVT-CGE-----MALCESLLKGLKQEWALV--- 293 ++NKL L+P+ VG LP R + ++GAD+ C E M C+ ++ + V Sbjct: 10 YHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDFVAPD 69 Query: 294 --------KRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG 345 +R + +F Q+ ++ VA+L++ ++ ID+N+GCP K G Sbjct: 70 DRVVFRTCEREQNRVVF--QMGTSDAERALAVARLVEN--DVAGIDVNMGCPKQYSTKGG 125 Query: 346 GGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVH 405 G+ ++ +E + K P T K+R + + T ++V ++ G + I VH Sbjct: 126 MGAALLSDPDKIEKILSTLVKGTRRPVTCKIR--ILPSLEDTLSLVKRIERTGIAAIAVH 183 Query: 406 GRSREARYTKSSDWEYIETCAQAATPCPVYGNG----DIFSYEDYVEMRKIAPTVKGVMI 461 GR RE R E I+ A + PV NG I Y D + R+ A VM+ Sbjct: 184 GRKREERPQHPVSCEVIKAIADTLS-IPVIANGGSHDHIQQYSDIEDFRQ-ATAASSVMV 241 Query: 462 GRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEH 502 R A+ P IF +KE + E+++KY Y +++ Sbjct: 242 ARAAMWNPSIF--LKE------GLRPLEEVMQKYIRYAVQY 274 >UniRef50_A7AAN4 Cluster: Putative uncharacterized protein; n=2; Bacteroidales|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 320 Score = 72.1 bits (169), Expect = 4e-11 Identities = 52/220 (23%), Positives = 100/220 (45%), Gaps = 5/220 (2%) Query: 292 LVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM 351 LV T Q+ +P ++A L +E+ D+N+GCP + ++ G+G++ Sbjct: 54 LVPEANTSASLVPQMIAASPEEFRRIAGLFRESGYRR-ADINLGCPFPMQARQHRGAGIL 112 Query: 352 HRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREA 411 ++ + + I F+VK+R G + + ++P ++ + +T+H R Sbjct: 113 PYPDEVKVLLETIFEFPEIQFSVKLRLG-WDSPEEAQALLPFLNGLPLTHLTLHPRIGTQ 171 Query: 412 RYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWI 471 +Y +D + T P++ NGDI + D + P +KG+MIGRG L PW+ Sbjct: 172 QYKGKTDLSAFSRFYDSCT-LPLFYNGDIRTLPDIRSLTGRFPRLKGIMIGRGLLSSPWL 230 Query: 472 FNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVE 511 E ++++++ E L + L + S +G E Sbjct: 231 ATEYISDT--PLTAQEKIEKLSAFHALLLAGYSSRLEGGE 268 >UniRef50_Q73RG6 Cluster: Dihydrouridine synthase, putative; n=1; Treponema denticola|Rep: Dihydrouridine synthase, putative - Treponema denticola Length = 337 Score = 71.7 bits (168), Expect = 5e-11 Identities = 73/261 (27%), Positives = 115/261 (44%), Gaps = 20/261 (7%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 KL +P+ + + FRR+ F D EM S + G E + + + + Sbjct: 2 KLISAPMAAITHSAFRRLAACFKEPDEYFSEMIHAPSAISGGGFEKWYFRANPSPEKLVW 61 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETS---- 360 QI + LL + IDLN+GC I G G M + P ET+ Sbjct: 62 QITSPDEKSAAACVPLLLQYGGFG-IDLNMGCCAPQIVNTGAGFAWMKK-PLSETASLVS 119 Query: 361 -VRCASKLLS----------IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSR 409 V+ A L I +VK+R G ++ + + + G LIT+H R++ Sbjct: 120 KVKKAVLLYDEQKAGPQTEPIRLSVKLRLGEEENYDRLLSFCKMLVSEGVDLITLHPRTQ 179 Query: 410 EARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKP 469 + +Y++ EY A + PVYGNGDI S E ++ P G MIGR A+ KP Sbjct: 180 KQKYSRPCKHEYTARLASDLS-VPVYGNGDINSLETLEKIASKYPCA-GWMIGRAAVQKP 237 Query: 470 WIFNEIKEQKIWDISSKDRFE 490 WIF E+ + + + +++D+ E Sbjct: 238 WIFYELSKGILKNGTAEDKDE 258 >UniRef50_Q4D174 Cluster: Dihydrouridine synthase (Dus), putative; n=2; Trypanosoma cruzi|Rep: Dihydrouridine synthase (Dus), putative - Trypanosoma cruzi Length = 548 Score = 71.7 bits (168), Expect = 5e-11 Identities = 49/177 (27%), Positives = 83/177 (46%), Gaps = 7/177 (3%) Query: 297 ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPA 356 ET+ Q CGN+ + A+ ++++ E +D+N+GCP + + GS +M Sbjct: 177 ETDHPLFVQFCGNDADTLLAAARHVEDDCEA--VDVNLGCPQGIARRGHYGSFLMEDWDR 234 Query: 357 LETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS 416 + + C + L +P T KMR V+ D +T + + G +++ VHGR+R + Sbjct: 235 VHNILHCLAVELRVPVTAKMR--VFDDDALTLKYAEMLRDTGIAVLCVHGRTRHNK-RGI 291 Query: 417 SDWEYIETCAQ-AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 +D E I + PV GNG++ ++ED V A G M L P +F Sbjct: 292 ADMEKIRRVREHLRGSIPVIGNGNVLTFED-VRRNMSATMTDGYMCAEPLLWDPRLF 347 >UniRef50_A6VYA3 Cluster: TIM-barrel protein, yjbN family; n=8; Proteobacteria|Rep: TIM-barrel protein, yjbN family - Marinomonas sp. MWYL1 Length = 341 Score = 70.9 bits (166), Expect = 9e-11 Identities = 59/235 (25%), Positives = 103/235 (43%), Gaps = 16/235 (6%) Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334 EM +LL+G E ++ E E Q+ G++ + K A++ E D ++LN+ Sbjct: 49 EMVTTGALLQGNHPE-RFLRYDECEHPIALQLGGSDAVALGKCAKMA-EQAGFDEVNLNV 106 Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGV--YQDKKITHTIVP 392 GCP D + G+ +M ++ ++R SIP T+K R G+ +D + V Sbjct: 107 GCPSDRVQNSLIGACLMAHPDKVKEAMRAMQDNCSIPVTIKHRIGLDDQEDYSVVRDFVG 166 Query: 393 KMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444 ++ G + VH R+ +E R + Y+ + + NG I + + Sbjct: 167 DVATTGVTTFIVHARNAILEGLSPKENREVPPLKYHYVHQLKKDFPDLEIIINGGIKTLD 226 Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKI-WDISSKDRFEILKKYSNY 498 E ++ V GVM+GR A PWI +++ E DR+E L+ + Y Sbjct: 227 ---ECKEQLAHVDGVMVGREAYHNPWILSQVDEVLFGGQPLVNDRYEALEAFVPY 278 >UniRef50_Q5KPM6 Cluster: Putative uncharacterized protein; n=2; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 407 Score = 70.9 bits (166), Expect = 9e-11 Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 8/172 (4%) Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 AQ N + A+L+ + +D IDLN GCP Y +G G ++ + + VR Sbjct: 154 AQFASPNAKSLADAAELI--SPYVDGIDLNCGCPQRWAYNEGIGCALLRKPELVRDMVRG 211 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW---E 420 + + V ++ + +++ T ++ G S +T+HGR+R T + + Sbjct: 212 VKDRMGWGWPVSIKIRIDSEQEKTEQLISNALQAGISHLTIHGRTRHQPSTDPVNLPGIK 271 Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 + C + PC NGD++ ED +MR + V+GVM RG L P +F Sbjct: 272 FAVDCVKGEVPC--VANGDVWELEDARQMR-LHTGVQGVMAARGLLANPALF 320 >UniRef50_Q4WRF0 Cluster: Dihydrouridine synthase family protein, putative; n=9; Pezizomycotina|Rep: Dihydrouridine synthase family protein, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 541 Score = 70.5 bits (165), Expect = 1e-10 Identities = 52/173 (30%), Positives = 82/173 (47%), Gaps = 8/173 (4%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q C N+P + A+ + D +DLN+GCP + K G+ + + + Sbjct: 130 QFCANDPDDFLEAARHVAPYC--DAVDLNLGCPQGIARKGHYGAFLQEDWDLIYKLINRL 187 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEYI 422 K L IP T K R + + K+ T + + GAS+IT+HGR+RE + T +DW YI Sbjct: 188 HKELPIPVTAKFR--IQESKEKTLEYAKMILSAGASIITLHGRTREQKGHNTGLADWSYI 245 Query: 423 ETCAQAATP-CPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 P ++ NG+ +++D +E A GVM G L P IF++ Sbjct: 246 RYLRDNLPPETVIFANGNNLNHDD-LERCLEATGADGVMSAEGNLSDPAIFSK 297 >UniRef50_UPI0000499E32 Cluster: conserved hypothetical protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved hypothetical protein - Entamoeba histolytica HM-1:IMSS Length = 339 Score = 70.1 bits (164), Expect = 2e-10 Identities = 59/229 (25%), Positives = 105/229 (45%), Gaps = 9/229 (3%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHET-EDLF 302 N + L+P+ +L FR + + G ++ M L + ++ +V + E Sbjct: 21 NPQNILAPMVDGSDLTFRILVRRHGVNLCYTPMVLSKMFVESKVYRNEVVNSLDPKEQPI 80 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 QI G++ + + A+ LQ + D ID+N+GCP + K G+ + + V Sbjct: 81 IIQIVGSDANEMARTAKFLQ--SYCDAIDINLGCPQKIAQKGNYGAYLALDFDHTKEIVN 138 Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWE 420 + ++IP K+R V++D++ T V + G I VHGR+ + + + + W Sbjct: 139 AVIEAVNIPVYCKVR--VFEDEEKTMRFVEMLQECGIWGIAVHGRTITEKQSMNYHARWN 196 Query: 421 YIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKP 469 YI + PV NG++ S E E +K+ + G MIG G L+ P Sbjct: 197 YIAKIKE-RLKIPVIANGEMRSREKIEECKKVTHS-DGYMIGFGLLMNP 243 >UniRef50_Q1N033 Cluster: Putative uncharacterized protein; n=1; Oceanobacter sp. RED65|Rep: Putative uncharacterized protein - Oceanobacter sp. RED65 Length = 321 Score = 70.1 bits (164), Expect = 2e-10 Identities = 48/174 (27%), Positives = 81/174 (46%), Gaps = 6/174 (3%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G++P + + A E +++N GCP + + GG+ ++ + T + Sbjct: 68 QLLGSDPVAMAENACRAAE-LGAPVVNINFGCPSRFVNGRCGGAYLLQFPDQIHTILESV 126 Query: 365 SKLL--SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 K L +P T KMR G ++D + M + G I +H R++ Y + W I Sbjct: 127 RKALPEHVPLTAKMRLG-FKDDALALANAQAMESAGVRDICIHARTKVQGYRPPAHWHQI 185 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIK 476 + Q P+ NG+I++ DY E K A + VM+GRGA+ P + IK Sbjct: 186 KNIKQ-QVKVPIIANGEIWNRRDY-EACKAASHCEHVMLGRGAVADPELAATIK 237 >UniRef50_Q0IFC6 Cluster: tRNA-dihydrouridine synthase; n=2; Culicidae|Rep: tRNA-dihydrouridine synthase - Aedes aegypti (Yellowfever mosquito) Length = 391 Score = 70.1 bits (164), Expect = 2e-10 Identities = 59/244 (24%), Positives = 105/244 (43%), Gaps = 8/244 (3%) Query: 231 IKLLPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEW 290 ++ L RE + D K+ +P+ L FR + + +G D+T M + +S + K Sbjct: 10 VEHLFREARAKDSYLKI-CAPMVRYSKLEFRNLVRSYGTDLTFTSMIMADSFCQSEKARL 68 Query: 291 ALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGM 350 + + AQ N ++ +D +DLN GCP + G GS + Sbjct: 69 NEFTTNRDDTPVIAQFAAKNAVDFLSATEMTFPY--VDGVDLNCGCPQRWAMQDGYGSAL 126 Query: 351 MHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTI--VPKMSNWGASLITVHGRS 408 + + + + L F+V ++ + Q K ++ TI ++ G + ITVHGR+ Sbjct: 127 LRTPELIADMLSTVRRNLPSTFSVSVKVRLLQ-KSLSATIDMCRQLEACGITFITVHGRT 185 Query: 409 REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIK 468 + + E ++ +++ PV NGDIFS +D + GVM RG L Sbjct: 186 PAQKTNIPVNQEALKE-IKSSLGIPVVANGDIFSLQD-ADAMHCKTNCDGVMSARGILSN 243 Query: 469 PWIF 472 P ++ Sbjct: 244 PAMY 247 >UniRef50_A6P2M8 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 311 Score = 69.7 bits (163), Expect = 2e-10 Identities = 42/150 (28%), Positives = 76/150 (50%), Gaps = 2/150 (1%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389 ++LN+GCP + KG GSG++ R LE + + ++K R G++ ++ H Sbjct: 81 VNLNLGCPSGTVTAKGKGSGLLARREELEQLLDGIFAAAPMAISIKTRLGMHDPEEFGH- 139 Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449 ++ + + + +TVH R R Y K EY + + + P+ NGDI + D+ + Sbjct: 140 LLELYNRYPVAELTVHPRIRGDFYKKPVRPEYFDLAVRMSR-APLCYNGDIITPGDWEKA 198 Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIKEQK 479 + P V+ VMIGRG + P + +K ++ Sbjct: 199 SQRWPGVETVMIGRGLVADPSLAGRLKGEQ 228 >UniRef50_A4AAB0 Cluster: TRNA-dihydrouridine synthase C; n=2; unclassified Gammaproteobacteria|Rep: TRNA-dihydrouridine synthase C - Congregibacter litoralis KT71 Length = 328 Score = 69.3 bits (162), Expect = 3e-10 Identities = 48/167 (28%), Positives = 80/167 (47%), Gaps = 6/167 (3%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 QI G +P ++ + A E +DLN GCP + + GGS ++ + V Sbjct: 74 QILGGDPSVVAENASRAAE-LGAPGVDLNFGCPAKTVNRSDGGSIILREPERVHRIVAAT 132 Query: 365 SKLL--SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 + L S+P +VK+R G + IV + S + +H R+R Y + WE+I Sbjct: 133 RQALPPSVPLSVKIRLGFDSSDRFL-DIVSGIDAARPSELVIHARTRADGYRPPAYWEHI 191 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKP 469 A++ T P+ NG+I+ D R+ + T + +M+GRG L +P Sbjct: 192 -ALARSKTRLPLIANGEIWGVGDAKLAREKSGT-RDLMLGRGVLCRP 236 >UniRef50_O74731 Cluster: tRNA dihydrouridine synthase Dus2; n=1; Schizosaccharomyces pombe|Rep: tRNA dihydrouridine synthase Dus2 - Schizosaccharomyces pombe (Fission yeast) Length = 479 Score = 68.9 bits (161), Expect = 4e-10 Identities = 60/248 (24%), Positives = 113/248 (45%), Gaps = 26/248 (10%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWAL-------- 292 ++++NK+ L+P+ +G LP R + +GA++ G + ++LL G E + Sbjct: 4 LNYSNKVCLAPMVRIGELPMRLLALRYGANLVWGPEIVDKALLSGTPVERVVNDRINCID 63 Query: 293 -VKRHETEDLFGA----------QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLI 341 VK + LF Q+ +P + + A+L+ ++ IDLN GCP Sbjct: 64 FVKPPSNKVLFRVHPLEANRLIFQLGSASPELAVEAAKLVAN--DVAGIDLNCGCPKHFS 121 Query: 342 YKKGGGSGMMHRLPALETSVRCASKLLSIPF--TVKMRTGVYQDKKITHTIVPKMSNWGA 399 G G+G++ L + + + P+ ++ + + + K+ T +V ++ + G Sbjct: 122 VHAGMGAGLLKNQDRLVSILDALVNEIGKPYKISISCKIRLLETKEDTLKLVERICDTGV 181 Query: 400 SLITVHGRSREARYTKSSDWEYIETCAQAA--TPCPVYGNGDIFSYEDYVEMRKIAPTVK 457 ITVH R+ R T+ +D Y+ + NGD+ SY D +++ + V Sbjct: 182 RAITVHCRTTPMRNTEPADRSYLSEIVGVCRNKDVSILVNGDVLSYNDGLDVIE-KYGVD 240 Query: 458 GVMIGRGA 465 GV+I R A Sbjct: 241 GVLIARAA 248 >UniRef50_Q54QJ2 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 402 Score = 68.5 bits (160), Expect = 5e-10 Identities = 61/249 (24%), Positives = 112/249 (44%), Gaps = 19/249 (7%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLK------------- 287 +D+ NK ++P+ VG P R + +G D+ E + L+K + Sbjct: 28 MDYYNKKIMAPMVRVGTYPMRILAYNYGCDIAYSEELIDLKLMKSTRVVNEKLKTIDFIA 87 Query: 288 QEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGG 347 ++ L R +D+ G + A + N ++ +D+N+GCP + G G Sbjct: 88 KDQTLCYRTSEKDVRNVLQLGTASSMTALEAAKVVCN-DICALDINMGCPKFFSVQGGMG 146 Query: 348 SGMMHRLPALETSVRCASKLLS-IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHG 406 S ++ + ++ + + L+ IP T K+R + D++ T ++ + + G S I VH Sbjct: 147 SALLSKPETIKDILTTLKRNLNGIPITCKIRL-LSTDQE-TIDLLRIIESTGVSAIGVHC 204 Query: 407 RSREARYTKSSDWEYIETC-AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465 R R + W+ +E + A+ P+ NGDIF + D +E K V +MI RG Sbjct: 205 RMIPERPRDPAHWDRLENILSNASFSVPIIANGDIFEHAD-IEKIKKQTKVDSIMIARGV 263 Query: 466 LIKPWIFNE 474 + IF++ Sbjct: 264 VKNVSIFSK 272 >UniRef50_Q4S086 Cluster: Chromosome undetermined SCAF14784, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14784, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 505 Score = 68.1 bits (159), Expect = 6e-10 Identities = 45/144 (31%), Positives = 76/144 (52%), Gaps = 8/144 (5%) Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSD 418 VR AS+ LS+P T K+R V+++ + T + G L+TVHGR++E + T + Sbjct: 146 VRLASEKLSVPITCKIR--VFKEMEKTVRYAQMLEKAGCQLLTVHGRTKEQKGAMTGVAS 203 Query: 419 WEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478 WE+I QA PV+ NG+I D + V+GVM G L P +F E + Sbjct: 204 WEHIRAVRQAVN-IPVFANGNIQHLSDVTRCLQ-ETGVQGVMSAEGNLHNPALF-EGRSP 260 Query: 479 KIWDISSKDRFEILKKYSNYGLEH 502 +W++ +++ E+++K+ L + Sbjct: 261 PVWEM-AEEYLEVVRKHPPCSLSY 283 Score = 36.3 bits (80), Expect = 2.3 Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 3/41 (7%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG 345 Q C N+P + + A L Q+ D IDLN+GCP +I K+G Sbjct: 56 QFCANDPEVFVQAALLAQDYC--DAIDLNLGCP-QMIAKRG 93 >UniRef50_Q21L63 Cluster: Dihydrouridine synthase, DuS; n=1; Saccharophagus degradans 2-40|Rep: Dihydrouridine synthase, DuS - Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Length = 318 Score = 68.1 bits (159), Expect = 6e-10 Identities = 52/175 (29%), Positives = 78/175 (44%), Gaps = 6/175 (3%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G+NP + A E + IDLN GCP + + GG+ ++ + V Sbjct: 73 QLLGSNPSALAANAARAAELGAVA-IDLNFGCPAKTVNRHKGGACLLDETDTVFDIVNAV 131 Query: 365 SKL--LSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 K S P T K+R G Y ++ + GA+ + VH RS+ Y + W YI Sbjct: 132 RKATPASTPVTAKIRLG-YLNRDSYLRNAKAIEAAGANELCVHARSKTDGYQPPAYWHYI 190 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 + PV NG+I+S ED+ + M+GRG L KP + EIK+ Sbjct: 191 GDIRDNLS-IPVVANGEIWSLEDFKRCAE-QSKCSDFMLGRGLLAKPDLALEIKQ 243 >UniRef50_A4BWB1 Cluster: Putative uncharacterized protein; n=5; Bacteroidetes|Rep: Putative uncharacterized protein - Polaribacter irgensii 23-P Length = 317 Score = 68.1 bits (159), Expect = 6e-10 Identities = 44/194 (22%), Positives = 94/194 (48%), Gaps = 4/194 (2%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389 ++ N+GCP ++ K+G GSG++ + + + I ++KMR G Y++ + Sbjct: 90 LNWNLGCPYPMVTKRGMGSGLISDAEKINSILHKVHNESDILVSMKMRMG-YENPEEILG 148 Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449 ++P + + I +H R + Y +D E + C + +Y NGDI S + ++ Sbjct: 149 VLPILDTYPLKNIAIHARIGKQLYKGGTDLEAFQKCLDNSKH-KMYYNGDITSVVAFHKL 207 Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQG 509 ++ P++ MIGRG + P++ + IK K+RF++ +++ + + + + G Sbjct: 208 QERFPSIDHWMIGRGLIGDPFLPSMIKADT--TEYPKERFDVFREFHDRIYQEYDAALSG 265 Query: 510 VESTRRFLLEWLSF 523 + +L + F Sbjct: 266 PTPIKMKMLGFWEF 279 >UniRef50_Q7VKU5 Cluster: tRNA-dihydrouridine synthase C; n=118; Gammaproteobacteria|Rep: tRNA-dihydrouridine synthase C - Haemophilus ducreyi Length = 325 Score = 68.1 bits (159), Expect = 6e-10 Identities = 67/232 (28%), Positives = 105/232 (45%), Gaps = 21/232 (9%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G P + + AQL E ID N GCP + GG+ ++ + P L + CA Sbjct: 73 QLLGQYPQWLAENAQLAIELGSYG-IDFNCGCPSKTVNGSHGGAALL-KDPEL---IYCA 127 Query: 365 SKLL------SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARY-TKSS 417 +K + + P +VKMR G + I + GA ITVHGR+++ Y + Sbjct: 128 TKAIREAVPKAQPVSVKMRLG-WDCASQCFEIADAIQQAGADEITVHGRTKQDGYRAERI 186 Query: 418 DWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 +W+ I Q PV NG+I + + R+I G+MIGRGAL P + IK Sbjct: 187 NWQAIGQIQQRLN-IPVIANGEILDFNSAQKCREITACC-GLMIGRGALNTPNLSKVIK- 243 Query: 478 QKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWLSFLYRYVP 529 + ++ + ++L +Y N E G R + +WL +L + P Sbjct: 244 YNVAKMAWSEVLQLLYEYVNMPNER----DSGFYHVAR-IKQWLHYLDKAYP 290 >UniRef50_UPI00015B40A4 Cluster: PREDICTED: similar to tRNA-dihydrouridine synthase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to tRNA-dihydrouridine synthase - Nasonia vitripennis Length = 505 Score = 67.7 bits (158), Expect = 8e-10 Identities = 67/255 (26%), Positives = 116/255 (45%), Gaps = 23/255 (9%) Query: 238 RKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWAL----- 292 R + + +KL ++P+ +G LP R + E+GAD+ E + LL+ +++ + Sbjct: 50 RPRLTYADKLIMAPMVRIGTLPMRLLALEYGADIVYTEELIDWKLLRSVRRVNEVLGTVD 109 Query: 293 -VKRHETEDLFGAQICGNNPYIIT----------KVAQLLQENTELDFIDLNIGCPIDLI 341 + R + +F + ++ KVA+L+++ ++ ID+N+GCP Sbjct: 110 YIDRTDGTIVFRTSPIERDRVVLQLGTCDANRALKVAKLVEQ--DVAGIDVNMGCPKRFS 167 Query: 342 YKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASL 401 G G+ ++ + +R LSIP T K+R V + + T +V + + G S Sbjct: 168 ILGGMGAALLKQPEKASEILRTLVGGLSIPVTCKIR--VLGNVEDTLKLVDTLVDTGISA 225 Query: 402 ITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTV--KGV 459 ITVHGR+ + R + E+I+ A+ A PV NG E ++ K V Sbjct: 226 ITVHGRTVDERPQHPNRSEFIKRVAEHA-KIPVIANGGSKEIEKRADIFKFKKETGCSSV 284 Query: 460 MIGRGALIKPWIFNE 474 MI R A IF E Sbjct: 285 MIARAAEWNCSIFRE 299 >UniRef50_A2DYY3 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 313 Score = 67.7 bits (158), Expect = 8e-10 Identities = 70/248 (28%), Positives = 107/248 (43%), Gaps = 26/248 (10%) Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCG----EMALCESLLKGLKQEWALVKR--- 295 + NKL +P+ +L FR C E+GAD+ ++A+ S ++ +L+K Sbjct: 9 YKNKLIAAPMVRGSSLSFRLACLEYGADLVFSPGLVDLAIIGSTMEKDDNNISLIKVENG 68 Query: 296 ------HETEDLFGAQICG----NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG 345 H T + G I + P I K A + E ID+N GCP +G Sbjct: 69 HNRRIFHTTAEERGKLIIQLITVDGPNAI-KAADMCTEFAS--GIDINCGCPESFACHRG 125 Query: 346 GGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVH 405 GGS M +L + V+ +P +VKMR ++ + M + GA ITVH Sbjct: 126 GGSKM--QLESAVDVVKTLKMNSPLPISVKMRVKDTVEESL--QFAKAMVDAGAVAITVH 181 Query: 406 GRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465 GR + S D+E+++ C GNG I + D EMR + +MI A Sbjct: 182 GRLAADKRHGSVDYEHMKEIFDNIN-CAKIGNGGICNKADAAEMR-VKTGCDSIMIATAA 239 Query: 466 LIKPWIFN 473 L P +F+ Sbjct: 240 LKNPSVFS 247 >UniRef50_Q57V78 Cluster: TRNA-dihydrouridine synthase 1, putative; n=1; Trypanosoma brucei|Rep: TRNA-dihydrouridine synthase 1, putative - Trypanosoma brucei Length = 520 Score = 67.3 bits (157), Expect = 1e-09 Identities = 48/173 (27%), Positives = 82/173 (47%), Gaps = 10/173 (5%) Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 AQ CGN+P + A+ +++ E +D NIGCP + + GS +M L + Sbjct: 158 AQFCGNDPETVLAAARHVEDYCEA--VDFNIGCPQGIARRGHYGSFLMEDWELLHNILHA 215 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSRE--ARYTKSSDWEY 421 + L +P T KMR ++ D+ +T + + G ++ VHGR+RE + + +D Sbjct: 216 LAVELRVPVTAKMR--IFDDEALTLKYAEMLRDTGIYVLCVHGRTRENKGQQQQPADLRM 273 Query: 422 IETCAQ-AATPCPVYGNGDIFSYEDYVEMRKIAPT-VKGVMIGRGALIKPWIF 472 I + P+ NG++ ++ED R +A T +G M L P +F Sbjct: 274 IRRVHEHLRGSIPIIANGNVLTFEDV--PRNLAITGCEGYMCAEPLLWDPKLF 324 >UniRef50_O31546 Cluster: Probable tRNA-dihydrouridine synthase 2; n=10; Bacilli|Rep: Probable tRNA-dihydrouridine synthase 2 - Bacillus subtilis Length = 325 Score = 67.3 bits (157), Expect = 1e-09 Identities = 73/280 (26%), Positives = 124/280 (44%), Gaps = 15/280 (5%) Query: 249 LSPLTTVGNLPFRRICKEFGA-DVTCGEMALCESLLK--GLKQEWALVKRHETEDLFGAQ 305 L+P+ V ++ FR + E G DV E ES G + E E A Sbjct: 16 LAPMEDVTDVVFRHVVSEAGRPDVFFTEFTNSESYCHPDGKDSVRGRLTFTEDEQPIVAH 75 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCAS 365 I G+ P K++ + E +D+N+GCP+ + G GSG++ R PA+ + A+ Sbjct: 76 IWGDKPENFRKMSIGMAE-LGFKGLDINMGCPVPNVAGNGKGSGLICR-PAVAAELIQAA 133 Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425 K +P +VK R G Y D + + + +++H R+R + WE I Sbjct: 134 KAGGLPVSVKTRLG-YTDVDEWREWLTHILKQDIANLSIHLRTRAEMSKVDAHWELIPEI 192 Query: 426 A----QAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIW 481 + A + NGDI + +++ + V G+MIGRG P+ F KE K Sbjct: 193 KKLRDEVAPDTLLTINGDIPDRQTGLKLAE-QYGVDGIMIGRGIFTNPFAFE--KEPK-- 247 Query: 482 DISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLLEWL 521 + SSK+ ++L+ + + E+ + + + RF +L Sbjct: 248 EHSSKELLDLLRLHLDLHDEYSKEEARPYKPLPRFFKIYL 287 >UniRef50_UPI000023EA9A Cluster: hypothetical protein FG07217.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG07217.1 - Gibberella zeae PH-1 Length = 510 Score = 66.9 bits (156), Expect = 1e-09 Identities = 50/173 (28%), Positives = 77/173 (44%), Gaps = 8/173 (4%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q C N+P + A+ Q D +DLN+GCP + K G+ + + + Sbjct: 107 QFCANDPDALLSAAK--QVAPYCDAVDLNLGCPQGIARKGKYGAFLQEDQDLIFRLINIL 164 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR--YTKSSDWEYI 422 K L +P T K+R + K+ T + GAS++TVHGR RE + T ++W+ I Sbjct: 165 HKELPVPVTAKIR--ILDTKEETLAYAQNVLKAGASILTVHGRKREQKGHLTGLAEWQMI 222 Query: 423 ETCAQA-ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 + ++ NG+I D +E A GVM G L P IF + Sbjct: 223 RFLRDSLPKETVIFANGNILQEGD-IEKCLEATGADGVMSAEGNLSDPAIFTK 274 >UniRef50_Q6MNE4 Cluster: Dihydrouridine synthase family protein; n=1; Bdellovibrio bacteriovorus|Rep: Dihydrouridine synthase family protein - Bdellovibrio bacteriovorus Length = 323 Score = 66.9 bits (156), Expect = 1e-09 Identities = 40/150 (26%), Positives = 73/150 (48%), Gaps = 5/150 (3%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL--SIPFTVKMRTGVYQDKKIT 387 +DLN GCP + + GG+ ++ + V K + +P T K+R G + D Sbjct: 92 VDLNFGCPAKTVNRHDGGASLLKSCDRVFNIVDTVRKAVPADVPVTAKIRLG-FDDPTKC 150 Query: 388 HTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYV 447 I + A+ +TVH R++ Y + W++I + T + NG+I++ D+ Sbjct: 151 LEIAQAVEEANATWLTVHCRTKTDGYKPPAYWDWIPKIKEK-TKIKLIANGEIWNVADFN 209 Query: 448 EMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 ++ + MIGRG + P+IF++IK+ Sbjct: 210 RCVEVTQC-EDYMIGRGVMSNPFIFSQIKQ 238 >UniRef50_Q583Y8 Cluster: TRNA-dihydrouridine synthase 4, putative; n=3; Trypanosoma|Rep: TRNA-dihydrouridine synthase 4, putative - Trypanosoma brucei Length = 419 Score = 66.9 bits (156), Expect = 1e-09 Identities = 57/227 (25%), Positives = 93/227 (40%), Gaps = 10/227 (4%) Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309 +P+ FR++C+ +G D++ M + +S A + E Q+ + Sbjct: 64 APMVRCSRPAFRKLCRLWGTDISYTHMIMADSFACSEAARQAEFSIYSGETRLITQLASS 123 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL- 368 + A ++ D IDLN GCP + G G+ ++ + +VRC L Sbjct: 124 SGPTAATAAAIVAP--WCDAIDLNCGCPQRRVMADGLGAALLRNPEVVADTVRCVRNALE 181 Query: 369 ---SIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETC 425 +P VKMR V D +++ + GA+ ITVHGR+ ++ I T Sbjct: 182 GGVELPCVVKMR--VKDDVRLSVDFARQCEAAGAAWITVHGRTPNCSAHAPVRFDAINTI 239 Query: 426 AQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 + A PV NG + ++ + V GVM G G L P F Sbjct: 240 RE-ALGVPVVANGGVRDPSTALQ-AALTAGVGGVMSGMGLLANPACF 284 >UniRef50_A2F0D1 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 333 Score = 65.7 bits (153), Expect = 3e-09 Identities = 71/269 (26%), Positives = 110/269 (40%), Gaps = 23/269 (8%) Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQE----------WAL 292 + K++ P+ NLPFR +C E GAD G +S+L E W Sbjct: 9 YRGKIFAGPMVRASNLPFRLMCLENGADGVYGPATSVDSILASHYDENEDPYTMYFGWPK 68 Query: 293 ---VKRHETEDLFGA---QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG 346 V H G QI N+ + A ++ + D IDLN GCP +G Sbjct: 69 NPHVHFHTDPKEKGKLIFQILTNDASKAVQAASVVVKFA--DAIDLNCGCPESFATSRGT 126 Query: 347 GSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHG 406 GS +M + V + ++P +VK R ++ I + N GAS I VHG Sbjct: 127 GSSLMSEPEIVADVVSALRRNYNVPISVKHRIHHNIEESIQFAVA--CENAGASAIAVHG 184 Query: 407 RSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGAL 466 R +E + S ++ ++ + GNG + + E EM + + V+I AL Sbjct: 185 RLKEQKNKGSVAYDNMKLVFDHLHVAKI-GNGGVKNREMAKEMME-KTGCESVIISSAAL 242 Query: 467 IKPWIFNEIKEQKIWDISSKDRFEILKKY 495 P IF+ E ++ + EI K+Y Sbjct: 243 KNPTIFSGHPETDPVKLARR-YLEIAKQY 270 >UniRef50_A1AT39 Cluster: Dihydrouridine synthase, DuS; n=7; Desulfuromonadales|Rep: Dihydrouridine synthase, DuS - Pelobacter propionicus (strain DSM 2379) Length = 342 Score = 65.3 bits (152), Expect = 4e-09 Identities = 46/191 (24%), Positives = 85/191 (44%), Gaps = 4/191 (2%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G+ + +Q Q+ I+LN+GCP + G GM+ L + + Sbjct: 98 QLIGHGREALVSGSQAAQD-AGAAHINLNMGCPYGRMTSGQTGGGMLRSPQELSSIIPAL 156 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 K + F++K+R+G Y + + ++P G + +H R+ +Y +D Sbjct: 157 RKTIRGTFSIKLRSG-YDNPRQIFDLLPLFEASGVDFLVLHPRTVLQKYAGFADHGITAE 215 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDIS 484 Q +T P+ NGDI S + + G+M+GRGA+ P +F ++ D Sbjct: 216 AVQRST-LPIIANGDIRSVATGRHVLR-ETGAAGLMLGRGAISDPLLFQRLRNCAPPDPQ 273 Query: 485 SKDRFEILKKY 495 ++R +L +Y Sbjct: 274 PQERAAMLSRY 284 >UniRef50_Q09504 Cluster: Uncharacterized tRNA-dihydrouridine synthase-like protein C45G9.2; n=2; Caenorhabditis|Rep: Uncharacterized tRNA-dihydrouridine synthase-like protein C45G9.2 - Caenorhabditis elegans Length = 284 Score = 64.9 bits (151), Expect = 6e-09 Identities = 50/216 (23%), Positives = 101/216 (46%), Gaps = 6/216 (2%) Query: 258 LPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKV 317 L FR++ + + DV M ++ ++ K + + E + Q ++P+++++ Sbjct: 7 LAFRQLVRVYDVDVCFTPMIYAKNFIESEKCRSSELSVCEGDSPLIVQFATDDPFVLSEA 66 Query: 318 AQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIP-FTVKM 376 A+++ + + +DLN GCP + KG GS ++ + L VR + P F+V + Sbjct: 67 AEMVYKCST--GVDLNCGCPKHDVRSKGFGSALLSKPELLADMVRQTRARIPDPDFSVSL 124 Query: 377 RTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYG 436 + + D + T + K G + +TVHGR+ R + D + + + + P+ Sbjct: 125 KIRINHDIEKTVDLCRKAEAAGVTHLTVHGRTPSQR-AEPIDIQALRIVKDSVS-VPIIA 182 Query: 437 NGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 NG I + E+ + + + V G+M G L P +F Sbjct: 183 NGGITTREEALFLAE-QTGVDGIMAANGLLDNPALF 217 >UniRef50_A4BCJ5 Cluster: NifR3/Smm1 family protein; n=2; Gammaproteobacteria|Rep: NifR3/Smm1 family protein - Reinekea sp. MED297 Length = 314 Score = 64.5 bits (150), Expect = 8e-09 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 6/173 (3%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G++P + + A L +DLN GCP + GG+ ++ ++ VR Sbjct: 68 QLLGSHPQALAENA-LRAIELGSHGLDLNFGCPSKTVNASKGGAVLLTEPESIYAVVRSV 126 Query: 365 SKLLSIPFTV--KMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 L T+ KMR G ++D + + + GA+ I VH R+++ YT + W ++ Sbjct: 127 RDALPGDQTLSAKMRLG-FEDNSLMWECAHAIRDGGANEIIVHARTKQQGYTPPAYW-HL 184 Query: 423 ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 +A P+ NG+I++ D + A +M+GRGA+ PW+ +EI Sbjct: 185 PADFEARLGIPMIINGEIWTPADAGRAQHEA-NCSSIMLGRGAVRNPWLASEI 236 >UniRef50_A2FU21 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 322 Score = 64.1 bits (149), Expect = 1e-08 Identities = 53/198 (26%), Positives = 97/198 (48%), Gaps = 12/198 (6%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ GN+ + A+ LQ+ ID+N GC + + G M++ + + Sbjct: 76 QMSGNDESELIACAKDLQQFAV--GIDINCGCTQHIARRGQYGYFMVNNENKRKNVIEMV 133 Query: 365 SKL---LSIPFTVKMRTGVYQDKK----ITHTIVPKMSNWGASLITVHGRSREARYTKSS 417 + +++P ++K R +D K IT ++ + G SLI+VHGR++ + Sbjct: 134 KNIVASINVPLSIKFRLIDGEDGKPDVDITCKFAKELEDAGVSLISVHGRAKNSNKAGPV 193 Query: 418 DWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKE 477 D E I A++ + PV NG + + E+ +EM K + GVM+G+G L+ P F++ E Sbjct: 194 DAEAIRKIAESVS-IPVMANGGVRTKEEAIEMFKESHAA-GVMVGQGLLMNPKAFSDTPE 251 Query: 478 QKIWDISSKDRFEILKKY 495 I S++ ++ K+Y Sbjct: 252 HDPVAI-SREYLQLWKEY 268 >UniRef50_Q22A31 Cluster: TIM-barrel protein, yjbN family; n=1; Tetrahymena thermophila SB210|Rep: TIM-barrel protein, yjbN family - Tetrahymena thermophila SB210 Length = 480 Score = 63.3 bits (147), Expect = 2e-08 Identities = 52/207 (25%), Positives = 89/207 (42%), Gaps = 13/207 (6%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ GN+P + K A++ +E D ++LN+GCP D + G+ +M + +R Sbjct: 163 QLGGNDPDNLAKAAKICEE-IGYDEVNLNVGCPSDRVQSGKFGACLMKEPELVAEIMRKM 221 Query: 365 SKLLSIPFTVKMRTGV--YQDKKITHTIVPKMSNWG-ASLITVHGRS--------REARY 413 + SIP TVK R GV + + + +S G VH R + R Sbjct: 222 KEACSIPVTVKCRLGVDNFDSYEFARDFIKTVSEKGQVQHFVVHARKAFLKGLNPAQNRN 281 Query: 414 TKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473 ++Y+ Q NG +Y+ ++ K + G M+GR A PW+F+ Sbjct: 282 VPPLKYDYVLRLKQEFPHLHFSINGGFKTYDQISDILKQENGLHGCMLGRAAYETPWLFS 341 Query: 474 EIKEQKIWDIS-SKDRFEILKKYSNYG 499 ++ + + R EIL+ + YG Sbjct: 342 DMDRRYFGKQNPGFSRREILQIWGQYG 368 >UniRef50_Q550J6 Cluster: Putative uncharacterized protein; n=2; Dictyostelium discoideum|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 392 Score = 62.9 bits (146), Expect = 2e-08 Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 10/179 (5%) Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIY--KKGGGSGMMHRLPALETSV 361 AQ GN P + A++ E D +D+N+GCP + K+ G+ ++ + V Sbjct: 72 AQFFGNKPEYFYESAKIANE-LGYDGVDINMGCPSRKVLSPKQASGAALITNPSLAKEIV 130 Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 + + L+ V ++T + DK +P + + +T+H R+++ + WE+ Sbjct: 131 KITKEALNFEKPVSVKTRIGFDKIEIDEWIPLILESEPACLTLHLRTKKELSLVPAHWEH 190 Query: 422 ------IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 +E Q + + GNGD+ +YE ++ + GVMIGR PW+FN+ Sbjct: 191 QVLDRVVELRNQISPNTLLVGNGDVETYEQGIDYINQFG-IDGVMIGRAVYGNPWLFNK 248 >UniRef50_Q5KGP0 Cluster: Putative uncharacterized protein; n=3; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 496 Score = 62.5 bits (145), Expect = 3e-08 Identities = 61/252 (24%), Positives = 109/252 (43%), Gaps = 24/252 (9%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLL---------KGL----K 287 I++ NKL L+P+ G+LP R + +GA + + +++ G+ K Sbjct: 104 INYKNKLVLAPMVRTGSLPMRLLSLYYGAGLVWSPEVVDRAIIGAERSVDPVTGVITYHK 163 Query: 288 QEWALVKRHETEDLFGA-QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG 346 + + H E F QI +NP + K AQ +Q+ ++ IDLN GCP G Sbjct: 164 GQGPIFSTHPAEKPFLIFQIGSSNPELAVKAAQTVQQ--DVAGIDLNCGCPKPFSTHAGM 221 Query: 347 GSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHG 406 G+ ++ L +R + +P + K+R + + T + ++ G +TVH Sbjct: 222 GAALLSTPELLLDILRALLDSIPLPISCKIR--LLPTQPSTLYLASRILRTGVRNLTVHC 279 Query: 407 RSREARYTKSSDWEYIETCAQAA--TPCPVYGNGDIFSYEDYVEMRK----IAPTVKGVM 460 R+R+ R + + WE + + + V NGD + ++ +R A VM Sbjct: 280 RTRQMRPGERALWERLSSIVELGKRRGISVICNGDGEGWSNWDRIRNETGMCASCADSVM 339 Query: 461 IGRGALIKPWIF 472 + R A P +F Sbjct: 340 LARSAERNPSVF 351 >UniRef50_A7EMF2 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 342 Score = 62.1 bits (144), Expect = 4e-08 Identities = 56/228 (24%), Positives = 93/228 (40%), Gaps = 9/228 (3%) Query: 250 SPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGN 309 +P+ L FR ++G D+ M L + + + + T AQ Sbjct: 35 APMVRYSKLAFRETVAQYGVDLCWTPMILAKEFNRSVFARDSDFTTSPTSTPTIAQFGVC 94 Query: 310 NPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLS 369 +P I++ L+ ++ ID+N GCP G+ +MH+ + V+ A L Sbjct: 95 SPLEISRSTTLIAPY--INGIDINCGCPQSWACACSIGAALMHKRELVAEMVKEAKSALK 152 Query: 370 IPF-----TVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIET 424 TV ++ +++D + T + + + G IT+HGR R + + E I+ Sbjct: 153 REGYEGKKTVSVKIRIHRDLRDTVDFIKTVQDAGVDFITIHGRMRSTPSSHPVNLEAIK- 211 Query: 425 CAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 T P NGDI S E + +V GVM RG L P +F Sbjct: 212 LLNTHTTVPTVSNGDITSLRSAHEHTQ-QTSVSGVMSARGLLSNPALF 258 >UniRef50_A2ACC0 Cluster: Novel protein; n=17; Eumetazoa|Rep: Novel protein - Mus musculus (Mouse) Length = 194 Score = 61.3 bits (142), Expect = 7e-08 Identities = 41/136 (30%), Positives = 71/136 (52%), Gaps = 9/136 (6%) Query: 296 HETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRL 354 + E+L+ +C + +I + A L Q+ D IDLN+GCP +I K+G G+ + Sbjct: 60 YRKENLY-CDVCPEDRPLIVQAALLAQDYC--DAIDLNLGCP-QMIAKRGHYGAFLQEEW 115 Query: 355 PALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREAR-- 412 L+ + A + LS+P T K+R DK + + + G L+TVHGR++E + Sbjct: 116 DLLQRMILLAHERLSVPVTCKIRVFPEIDKTVRY--AQMLEKAGCQLLTVHGRTKEQKGP 173 Query: 413 YTKSSDWEYIETCAQA 428 ++ WE+I+ +A Sbjct: 174 MAGTASWEHIKAVRKA 189 >UniRef50_Q4UGK9 Cluster: Putative uncharacterized protein; n=2; Theileria|Rep: Putative uncharacterized protein - Theileria annulata Length = 359 Score = 61.3 bits (142), Expect = 7e-08 Identities = 59/232 (25%), Positives = 97/232 (41%), Gaps = 22/232 (9%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETED--LFG 303 K ++P+ LPFR +C+ + AD+ M + + + + + H + D Sbjct: 27 KFIVAPMVDQSELPFRLLCRRYSADLAYTPM--LHAKIFSENENYRNIHFHTSSDDKPLI 84 Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 AQ CGN+P + ++ ++ ID+N+GCP I KKG + P L T Sbjct: 85 AQFCGNDPSAFILASSYIK--NDVSAIDINLGCP-QGIAKKGRYGSFLLEYPQLITK--- 138 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSS--DWEY 421 + F + R ++ V G +TVHGR R T+ S DW+ Sbjct: 139 GFASVDTKFMLFTRGWLFS--------VQSCQANGCKALTVHGRHRSETKTRISECDWDS 190 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473 I+ ++ PV NG I ++ED V+ VM L P++F+ Sbjct: 191 IK-IIKSRVNIPVIANGGIETFED-VKRCLDYTGADAVMSSEAILENPYLFS 240 >UniRef50_Q4PAE4 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 766 Score = 61.3 bits (142), Expect = 7e-08 Identities = 60/262 (22%), Positives = 116/262 (44%), Gaps = 24/262 (9%) Query: 234 LPRERKTIDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCG----EMAL--CE------- 280 +P T+++ N ++L+P+ +G LP R + E+GAD+ G + A+ CE Sbjct: 65 IPVCTSTLEYRNGIFLAPMVRIGTLPTRLLSLEYGADLVWGPEIVDRAIIGCERKVNPHT 124 Query: 281 SLLKGLKQEWALVKRHETEDLFGA-QICGNNPYIITKVAQLLQENTELDFIDLNIGCPID 339 +++ LK + H E + Q+ +P++ + + + + ++ +DLN GCP Sbjct: 125 GVVEYLKDHKQIFSCHPIERPYLVYQLGSADPHLAFQAIKTITQADDVAAVDLNCGCPKP 184 Query: 340 LIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGA 399 G G+ M+ L +++ + V + + ++ T +V K+ GA Sbjct: 185 FSTHAGMGANMLSTPILLCNTLKAMRRAAPAHVAVTCKIRLLPTQEKTLELVDKIVRTGA 244 Query: 400 -SLITVHGRSREARYTKSSDW----EYIETCAQAAT----PCPVYGNGDIFSYEDYVEMR 450 +TVH R+++ R + + E ++ AT PV NGD++ ++ Sbjct: 245 IECLTVHCRTKDMRPREPALLHRLREIVDHVNSVATEMGRTIPVVCNGDVWDAATVPRIK 304 Query: 451 KIAPTVKGVMIGRGALIKPWIF 472 ++ V MI RGA P F Sbjct: 305 ELT-GVTSTMIARGAEANPSCF 325 >UniRef50_Q5SMC7 Cluster: TRNA-dihydrouridine synthase; n=2; Thermus thermophilus|Rep: TRNA-dihydrouridine synthase - Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) Length = 342 Score = 60.1 bits (139), Expect = 2e-07 Identities = 64/265 (24%), Positives = 124/265 (46%), Gaps = 20/265 (7%) Query: 246 KLYLSPLTTVGNLPFRRICKEFGADVTC-GEMALCESLLKGLKQEWALVKRHETEDLFGA 304 +L ++P+ + FR + ++ V EM + +++L+G +E L R E E Sbjct: 5 RLSVAPMVDRTDRHFRFLVRQVSLGVRLYTEMTVDQAVLRG-NRERLLAFRPE-EHPIAL 62 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G++P + + A++ E D I+LN+GCP + + G G+ ++ L + ++ Sbjct: 63 QLAGSDPKSLAEAARI-GEAFGYDEINLNLGCPSEKAQEGGYGACLLLDLARVREILKAM 121 Query: 365 SKLLSIPFTVKMRTGVYQDKKITHTI---VPKMSNWGASLITVHGRSR-EARYTKSS--- 417 + + +P TVKMR G+ + K+ + V M+ G + VH RS A TK++ Sbjct: 122 GEAVRVPVTVKMRLGL-EGKETYRGLAQSVEAMAEAGVKVFVVHARSALLALSTKANREI 180 Query: 418 ---DWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 +++ NG I S E+ + K V GVM+GR P++ E Sbjct: 181 PPLRHDWVHRLKGDFPQLTFVTNGGIRSLEEALFHLK---RVDGVMLGRAVYEDPFVLEE 237 Query: 475 IKEQKIWDISSK-DRFEILKKYSNY 498 +++++ + + R E+ ++ Y Sbjct: 238 -ADRRVFGLPRRPSRLEVARRMRAY 261 >UniRef50_Q83D40 Cluster: TIM-barrel protein, yjbN family; n=7; Bacteria|Rep: TIM-barrel protein, yjbN family - Coxiella burnetii Length = 353 Score = 59.7 bits (138), Expect = 2e-07 Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 17/237 (7%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTC-GEMALCESLLKGLKQEWALVKRHETEDLF 302 N ++ ++P+ + FR ++ V EM +LLKG ++W + E Sbjct: 28 NRRISIAPMMGCTDRHFRMFMRQISRHVLLYTEMVTTGALLKG--KQWRCLDYSPEEHPL 85 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 Q+ G++P + A+L +E D I+LN+GCP + G+ ++ + V Sbjct: 86 ALQVGGSDPQSLALCARLAEEKG-FDEINLNVGCPSGRVIAGRFGACLLKEAELVADCVA 144 Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHT--IVPKMSNWGASLITVHGRS--------REAR 412 S ++IP +VK RTGV H V ++ G + +H R E R Sbjct: 145 AMSAEVNIPVSVKTRTGVDDQDSYEHLYHFVKTVAEAGCRIFIIHARKAWLKGLSPAENR 204 Query: 413 YTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKP 469 + + Q + NG I + E + + V GVMIGR A P Sbjct: 205 TVPPLAYPMVYQLKQDFPGLEIIINGGIKTIEAINDHLR---EVDGVMIGREAYANP 258 >UniRef50_Q4FQ57 Cluster: Possible tRNA-dihydrouridine synthase; n=5; Moraxellaceae|Rep: Possible tRNA-dihydrouridine synthase - Psychrobacter arcticum Length = 350 Score = 59.3 bits (137), Expect = 3e-07 Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 12/166 (7%) Query: 318 AQLLQENT----ELDF--IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLL--S 369 AQL+ EN EL ID+N GCP + GGS ++ + + + + + Sbjct: 109 AQLMAENAAHACELGAPAIDINFGCPAKTVNSHRGGSVLLDEPEVMYDIISAVRQAVPAN 168 Query: 370 IPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAA 429 IP + K+R G Y D I ++ GA +T+H R++ Y + W+ I+ A + Sbjct: 169 IPVSAKIRLG-YTDTSRMDDIRGAIAASGADWLTIHARTKTQGYKPPAYWDKIQ--AFNS 225 Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 PV NG+I++ E + T +M+GRGA+ +P + ++ Sbjct: 226 LKIPVIANGEIWNSEHAQNCMAQSGTTH-LMLGRGAVTRPDLIAQV 270 >UniRef50_A4RU69 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 345 Score = 58.4 bits (135), Expect = 5e-07 Identities = 54/238 (22%), Positives = 96/238 (40%), Gaps = 19/238 (7%) Query: 243 WNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMAL------CESLLKG-------LKQE 289 + K +P+ + L R + E+GAD+ GE + C +L + + Sbjct: 11 YTGKNVCAPMVRISTLATRLLAHEYGADLVYGEELVDKRFMHCRRILNKELGSVDFIDAK 70 Query: 290 WALVKRH--ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGG 347 L R E + Q+ ++ K A+L+ + ID+N+GCP G G Sbjct: 71 GTLTFRTVPEERERVVFQVGTSSAASALKSAELVARDVAA--IDVNMGCPKHFSTSGGMG 128 Query: 348 SGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGR 407 + ++ + + + + L V + + + ++ T + + + G S VHGR Sbjct: 129 ARLLSQPELVRDILTTLRRNLPSTTHVTCKIRLLESERETAELAKMIESCGVSAFAVHGR 188 Query: 408 SREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465 R + + W I+ + A CPV NGD+ YED+ +R M RGA Sbjct: 189 YIPQRPREPAHWNLIKNVVE-AVDCPVIANGDVECYEDFARIR-AQTGAASAMCARGA 244 >UniRef50_Q3IKP0 Cluster: TRNA-dihydrouridine synthase C; n=5; Alteromonadales|Rep: TRNA-dihydrouridine synthase C - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 326 Score = 57.6 bits (133), Expect = 9e-07 Identities = 53/203 (26%), Positives = 89/203 (43%), Gaps = 8/203 (3%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTV--KMRTGVYQDKKIT 387 IDLN GCP + K GG+ ++ + ++ + V K+R G + D + Sbjct: 92 IDLNFGCPAKTVNKSKGGAVLLKDPEHMYEIIKAVRDAVDSKHQVSAKIRLG-FDDDSNS 150 Query: 388 HTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYV 447 IV + + GAS I +H R++ Y + WE I + V NG+I+ D + Sbjct: 151 QEIVDAVVSAGASSIAIHARTKRDGYNPPAYWEKIPPLIK-DKDIAVVANGEIWQVADAM 209 Query: 448 EMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFE-ILKKYSNYGLEHWGSD 506 +K + +M+GRGAL P + +IK + +E IL N + H + Sbjct: 210 LCQKRSGCT-DLMLGRGALSHPDLAKKIKANINNEHYVGLEWEHILYHLINSAIHHDPAK 268 Query: 507 TQGVESTRRFLLEWLSFLYRYVP 529 + ++R +WL +L R P Sbjct: 269 DEKYFASR--TKQWLGYLKRQYP 289 >UniRef50_A5Z3X7 Cluster: Putative uncharacterized protein; n=1; Eubacterium ventriosum ATCC 27560|Rep: Putative uncharacterized protein - Eubacterium ventriosum ATCC 27560 Length = 326 Score = 57.2 bits (132), Expect = 1e-06 Identities = 53/189 (28%), Positives = 88/189 (46%), Gaps = 17/189 (8%) Query: 305 QICGNNP-YIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV-- 361 QI N Y I QL++ + + I+LN GCP + K G+G + A++ Sbjct: 65 QILANRADYFIKAANQLIELGYDKE-INLNAGCPSGTVVSKNKGAGFLKDTEAMDRFFDE 123 Query: 362 ------RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTK 415 + S+ ++ +VK R G+Y+ + I+ + + S + VH R+RE Y Sbjct: 124 TFNWLEKKNSEGHNLSISVKTRIGMYEPDEF-ENILEVYNKYPISQLIVHPRTREQLYKG 182 Query: 416 SSDWEYIETCAQAATPCPVYGNGDIFSYEDYVE-MRKI----APTVKGVMIGRGALIKPW 470 + + E + + + PV NGDI + E+Y + KI + +MIGRG + P Sbjct: 183 TPNMEAFKYALENSKN-PVCYNGDINTVENYHRIIEKINDDSEMKIGSIMIGRGLIGNPN 241 Query: 471 IFNEIKEQK 479 + NEIK K Sbjct: 242 LVNEIKGGK 250 >UniRef50_Q4PBU9 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 477 Score = 56.4 bits (130), Expect = 2e-06 Identities = 45/195 (23%), Positives = 83/195 (42%), Gaps = 28/195 (14%) Query: 304 AQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRC 363 AQ + P ++L+ +D +DLN GCP Y++ GS ++ + + VR Sbjct: 171 AQFASSKPEPFADASELI--GRFVDGVDLNCGCPQPWAYEELLGSYLLRQPETVRDMVRA 228 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 + F V ++ + D ++T +V + GAS++ +HGR+R ++ + + I+ Sbjct: 229 VKARMGSDFCVSVKIRIDPDLRLTDALVRNALHAGASILQIHGRTRWQSSSEPVNLDGIK 288 Query: 424 TCAQAATPC-------------------------PVYGNGDIFSYEDYVEMRKIAPTVKG 458 AA C P NGD+++ +D + R+ +G Sbjct: 289 FAVDAANACGFRTSWGSKGGAAARFADGGSGGLVPCVANGDVWTLDDAIHYRQ-TTGCRG 347 Query: 459 VMIGRGALIKPWIFN 473 M RG L P +F+ Sbjct: 348 AMSARGLLANPALFS 362 >UniRef50_Q97DM0 Cluster: Predicted TIM-barrel enzyme, nifR3 family; n=17; Clostridiales|Rep: Predicted TIM-barrel enzyme, nifR3 family - Clostridium acetobutylicum Length = 311 Score = 56.0 bits (129), Expect = 3e-06 Identities = 36/166 (21%), Positives = 73/166 (43%), Gaps = 8/166 (4%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389 ++LN+GCP + KG G+G + + L+ + ++K R G + + Sbjct: 88 VNLNLGCPSGTVVSKGRGAGFLKKRQELDEFLEKIFSKSPAKISIKTRIGKDSPDEF-YE 146 Query: 390 IVPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449 ++ + + + +H R + Y + + + + + Y NGDIF DY+++ Sbjct: 147 LIKIFNKYPLEELIIHPRIQTDFYNNKPNMKVFKDALELSKSTVCY-NGDIFQSNDYIKL 205 Query: 450 RKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKY 495 + + VM+GRG + P I +I + + E+LKK+ Sbjct: 206 IEEFSNLGVVMLGRGIISNPNIIKKINSNNVLE------KEVLKKF 245 >UniRef50_Q7R1J1 Cluster: GLP_38_15456_16676; n=1; Giardia lamblia ATCC 50803|Rep: GLP_38_15456_16676 - Giardia lamblia ATCC 50803 Length = 406 Score = 56.0 bits (129), Expect = 3e-06 Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 7/117 (5%) Query: 305 QICGNNPYIITKVAQLLQEN---TELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361 Q+CGNNP A+LL ++ ++L +D+N+GCP KG G + P + + Sbjct: 118 QLCGNNPSTFRAAAELLHDSPIASQLVALDINLGCPASCASSKGYGFYVAQNWPLVHQII 177 Query: 362 RCASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGR--SREARYTKS 416 S P T K+R +K I + ++ MS GAS IT+H R +R+ ++ ++ Sbjct: 178 SETSSARLFPVTCKIRPLNSIEKTIDYMVLLVMS--GASGITIHMRHTTRQGKHAQA 232 >UniRef50_A1IED4 Cluster: Putative uncharacterized protein; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Putative uncharacterized protein - Candidatus Desulfococcus oleovorans Hxd3 Length = 324 Score = 55.6 bits (128), Expect = 4e-06 Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 2/139 (1%) Query: 333 NIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTIVP 392 N+GCP ++ KK G+G++ + + + +VK+R G + D ++P Sbjct: 93 NLGCPYPMVAKKYRGAGLLPHTDRIAEFLDTVMSRMKGGLSVKIRLG-WADTTELMGLLP 151 Query: 393 KMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKI 452 + + + + VH R+ RY + D E + T PV NGDI + D+ + Sbjct: 152 VLHRYPLAELIVHPRTGIQRYEGTVDLAAFERVLEN-TGLPVMYNGDIQTVADFAYLSGR 210 Query: 453 APTVKGVMIGRGALIKPWI 471 V MIGRGAL P++ Sbjct: 211 FKAVDRWMIGRGALADPFL 229 >UniRef50_A0EAZ6 Cluster: Chromosome undetermined scaffold_87, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_87, whole genome shotgun sequence - Paramecium tetraurelia Length = 346 Score = 55.6 bits (128), Expect = 4e-06 Identities = 50/206 (24%), Positives = 89/206 (43%), Gaps = 16/206 (7%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ GN+P + K AQ+ E D I+LN+GCP + + G+ +M + ++ Sbjct: 70 QLGGNDPEKLAKAAQIA-EQAGFDEINLNVGCPSERVQDGAFGACLMKEPHLVAQCMKKM 128 Query: 365 SKLLSIPFTVKMRTGV--YQDKKITHTIVPKMSNWG-ASLITVHGRS--------REARY 413 + + IP T+K R GV + V + G + +H R E R Sbjct: 129 KEAVKIPCTLKCRLGVDNLDSYEFVRNFVEIVYKEGEVNHFIMHARKAFLKGLNPHENRT 188 Query: 414 TKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473 ++++ + NG I E + ++ P V G+MIGR A PW+F+ Sbjct: 189 VPPLKYDWVYQLKKEFPEIKFTLNGGIKCTE---HIDQVLPNVDGIMIGRSAHENPWMFS 245 Query: 474 EIKEQKI-WDISSKDRFEILKKYSNY 498 + + + +R EIL++Y+ + Sbjct: 246 DFDRLYYGGENQNYNRKEILEQYAEF 271 >UniRef50_UPI0000DAE45A Cluster: hypothetical protein Rgryl_01000346; n=1; Rickettsiella grylli|Rep: hypothetical protein Rgryl_01000346 - Rickettsiella grylli Length = 330 Score = 55.2 bits (127), Expect = 5e-06 Identities = 58/247 (23%), Positives = 109/247 (44%), Gaps = 22/247 (8%) Query: 260 FRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQ 319 FR ICK+ A + EM +++LK +E L+ E Q+ G ++K A+ Sbjct: 29 FRLICKK--AQLYT-EMFTAQAILKSPARE-RLLTVDANEKALAIQLGGGIASDLSKAAK 84 Query: 320 LLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTG 379 ++ E+ I+LN+GCP + + G G ++ + ++ ++ +P TVK R G Sbjct: 85 IV-ESYGYSEINLNVGCPSEKVQSGGFGVVLLKEPNRVADAIAAMKAVVRLPVTVKTRIG 143 Query: 380 VYQDKKITH--TIVPKMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAA 429 V D+ + + + ++S G +H R +E R ++ ++ + Sbjct: 144 VDNDESYDYLASFIRQVSLAGCDTFIIHARKAWLHGVSPKENREIPPLNYPWVYQIKRDF 203 Query: 430 TPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRF 489 + NG I + + + V VMIGR A P++F ++ IS +DRF Sbjct: 204 PHLTIVLNGGITCLKRAYQQLQ---HVDAVMIGRAAWYNPYLFAQLDAL----ISPQDRF 256 Query: 490 EILKKYS 496 + ++S Sbjct: 257 IVPHRFS 263 >UniRef50_Q4FLD8 Cluster: Putative uncharacterized protein; n=2; Candidatus Pelagibacter ubique|Rep: Putative uncharacterized protein - Pelagibacter ubique Length = 330 Score = 55.2 bits (127), Expect = 5e-06 Identities = 55/237 (23%), Positives = 111/237 (46%), Gaps = 22/237 (9%) Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334 EM + E++ +G K++ L++ + E QI G++P ++ + ++ E+ D I+LN+ Sbjct: 34 EMVVSEAIHRGDKKK--LLEFNINEKPIALQIGGSSPTLLAEATKV-GEDFGYDEINLNL 90 Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSI---PFTVKMRTGV--YQDKKITHT 389 GCP + K G+ +M + P L C SK+ S+ P T+K R G +D + H Sbjct: 91 GCPSKKVEKNKFGACLM-KEPNLVAD--CLSKMQSVTKLPVTIKTRIGYDDTEDYENLHR 147 Query: 390 IVPKMSNWGASLITVHGRSR-EARYTKSSD-------WEYIETCAQAATPCPVYGNGDIF 441 + + + G +H R ++T + ++++ + + NG I Sbjct: 148 FISTLKSTGVKTFIIHARKAILGKFTPKQNLNIPPLKYDFVYRLKKDFPNEEIIINGGIT 207 Query: 442 SYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNY 498 + + +M+ V GVMIGR A P++ +I+ + + R +++++ Y Sbjct: 208 TTD---QMKDHLDKVDGVMIGRAAYHTPYLLADIERDIFNNENVPSRQDVIEQLLPY 261 >UniRef50_A2DHB4 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 312 Score = 55.2 bits (127), Expect = 5e-06 Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 16/214 (7%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALV--KRHETEDLFGA 304 ++L+P+ V + FR++C++ G + + KQ V + E Sbjct: 15 IFLAPMADVNDYSFRKLCRQNGVSLCWTGFINAHHWVTRTKQRDRDVWFTTRDNEKNLVV 74 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM----HRLPALETS 360 Q+ G+N + A+ + EN D I+LN GC + G G ++ HR AL Sbjct: 75 QLLGSNLEELVSCAKDV-ENF-CDMIELNCGCTHCFASRSGCGFFLIDTQKHRDSAL-IL 131 Query: 361 VRCASKLLSIPFTVKMRTGVYQDKKI-----THTIVPKMSNWGASLITVHGRSREARYTK 415 ++ K ++ P ++K+R + D + T + G SLITVH R+++A Sbjct: 132 IQNLIKSINKPVSIKIRL-ISDDNSVPSLERTVKFAQDLERVGVSLITVHARTQQADKKG 190 Query: 416 SSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEM 449 D++ I+ QA + PV NG I S E E+ Sbjct: 191 DVDYDAIKAVVQAVS-VPVIANGGISSLEQAQEI 223 >UniRef50_Q7R9R0 Cluster: Uncharacterized protein family UPF0034, putative; n=7; Plasmodium|Rep: Uncharacterized protein family UPF0034, putative - Plasmodium yoelii yoelii Length = 531 Score = 54.4 bits (125), Expect = 8e-06 Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 5/165 (3%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCG-EMALCESLLKGLKQEWALVKRHETEDLFGAQ 305 + ++P+ V N FR + + V EM + +LL + + ++ E Q Sbjct: 154 IQVAPMINVTNRHFRALVRIISKKVQLWTEMIVDNTLLYNINNLEEHLGFNKNEHPIVCQ 213 Query: 306 ICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRCA 364 + G++P +++ A +L E D I++N+GCP + KG G+ +M ++ V Sbjct: 214 LGGSDPTSLSEAA-ILVEQAGYDEININVGCPSTKVANKGAFGAYLMKNPQLVKNIVYEI 272 Query: 365 SKLLSIPFTVKMRTGV--YQDKKITHTIVPKMSNWGASLITVHGR 407 K + IP TVK+RTGV + + +S+ G +H R Sbjct: 273 KKKVQIPVTVKIRTGVDNLDSFSFLRSFIETVSSAGCDHFIIHSR 317 >UniRef50_A5WG83 Cluster: TIM-barrel protein, yjbN family; n=4; Moraxellaceae|Rep: TIM-barrel protein, yjbN family - Psychrobacter sp. PRwf-1 Length = 348 Score = 54.0 bits (124), Expect = 1e-05 Identities = 69/286 (24%), Positives = 113/286 (39%), Gaps = 20/286 (6%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTC-GEMALCESLLKGLKQEWALVKRHETEDLF 302 N +L ++P+ +R + F EM ++L+G L++ E Sbjct: 20 NKRLSVAPMIDWTTTDYRFFARLFNPHTYLYTEMISTSAILQGKTDR--LLRYDTLEHPL 77 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 Q+ G + +T+ A Q+ + +++N+GCP D + G+ +M + VR Sbjct: 78 VLQLGGADISEMTQCAVEAQKRG-FNEVNINVGCPSDRVQHNKIGACLMAEPDTVAALVR 136 Query: 363 CASKLLSIPFTVKMRTGV--YQDKKITHTIVPKMSNWGASLITVHGR--------SREAR 412 + IP TVK R G+ + + V + G VH R +E R Sbjct: 137 NMQAHVDIPVTVKHRIGIDEHDSYEFMQDFVSASAEAGCQRFIVHARIAWLNGLSPKENR 196 Query: 413 YTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 +E + QA + NG I S E +++ V GVMIGR A P+I Sbjct: 197 EIPPLRYEDVYRLKQAFPELHIEINGGIDSIE---QIKAHLQQVDGVMIGRAAYHNPYIL 253 Query: 473 NEIKEQKIWDISSKDRFEILKKYSNYGLEHWGSDTQGVESTRRFLL 518 E W ++ R +IL K Y LE + + + S R L Sbjct: 254 AE--AMSFWGEAAPSRAQILTKLYPY-LEQQVAKGEPLPSLARHFL 296 >UniRef50_Q04VP3 Cluster: TRNA-dihydrouridine synthase; n=4; Leptospira|Rep: TRNA-dihydrouridine synthase - Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) Length = 339 Score = 53.2 bits (122), Expect = 2e-05 Identities = 52/205 (25%), Positives = 88/205 (42%), Gaps = 15/205 (7%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G+NP + + +++ E+ I+LN+GCP D + + G+ +M + V Sbjct: 71 QLGGDNPKALAESSKI-GEDYGYSEINLNVGCPSDRVREGNFGACLMETPERVAELVCAM 129 Query: 365 SKLLSIPFTVKMRTGVYQDKKITH--TIVPKMSNWGASLITVHGR--------SREARYT 414 +SIP TVK R G+ + + + + G VH R + R Sbjct: 130 DGNVSIPVTVKCRIGISGKETLEDLCRFIECVRQAGVRRFIVHARIAILGGLSPAQNRQI 189 Query: 415 KSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 + ++E+ + + NG I EM+ T GVMIGR A P++F+E Sbjct: 190 PPLRYAHVESLKKEFPDLLIEINGGI---RTLAEMQDRLKTNDGVMIGRAAYETPYLFSE 246 Query: 475 IKEQKIWDIS-SKDRFEILKKYSNY 498 + D S S R E+L + +Y Sbjct: 247 VDSLFFHDNSPSLSRREVLLRMRDY 271 >UniRef50_Q4Q391 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania major Length = 493 Score = 53.2 bits (122), Expect = 2e-05 Identities = 61/251 (24%), Positives = 103/251 (41%), Gaps = 31/251 (12%) Query: 247 LYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQI 306 L +P+ FR++C+ +G V+ M + ES +K A R+E E+ AQ+ Sbjct: 98 LIQAPMVRCSRPAFRQVCRAWGTRVSYTHMLMAESFVKSPHARHAEFARYEGENRLVAQL 157 Query: 307 CGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM---HRLPALETSVR- 362 + + A LL+ D IDLN GCP K+G G+ ++ R+ + S+R Sbjct: 158 AAKSGPAAAQAALLLR--PYCDGIDLNCGCPQRWAMKEGIGAALLDQPERVADMVRSIRN 215 Query: 363 --------------------CASKLLS-IPFTVKMRTGVYQDKKITHTIVPKMSNWGASL 401 C S + +P VKMR + D + + + G S Sbjct: 216 AMPDGSTAPMIVGNGGEYSSCTSAVPPFLPCVVKMR--IKDDLRRSVDFARQCEAAGVSW 273 Query: 402 ITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMI 461 +TVHGR+ + + +E ++ + + PV NG + +E + G+M Sbjct: 274 LTVHGRTPTCHSSTAVQFEAVKLIRENLS-VPVVLNGGVTDVSTAME-AALRTGCGGLMS 331 Query: 462 GRGALIKPWIF 472 G L P +F Sbjct: 332 ANGLLDNPAMF 342 >UniRef50_Q9PGB5 Cluster: tRNA-dihydrouridine synthase A; n=8; Proteobacteria|Rep: tRNA-dihydrouridine synthase A - Xylella fastidiosa Length = 340 Score = 53.2 bits (122), Expect = 2e-05 Identities = 53/211 (25%), Positives = 95/211 (45%), Gaps = 17/211 (8%) Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334 EM ++++ G ++ L+ E Q+ G+ P ++ K A++ + + I+LN Sbjct: 47 EMVHAKAVIYGDRER--LLGFASVEQPVALQLGGSEPALLAKAARIAVDWGYSE-INLNC 103 Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITH--TIVP 392 GCP D + G+ +M + V + ++S+P TVK R GV +D V Sbjct: 104 GCPSDRVQAGSFGARLMREPALVADCVAAMAAVVSVPVTVKCRLGVNEDDDYGRFAKFVD 163 Query: 393 KMSNWGAS-LITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSY 443 +S +S +I VH R+ +E R ++++ + V NG I S Sbjct: 164 WVSRASSSRMIVVHARNAWLQGLSPKENREIPPLRYDWVYRLKRERPELAVVLNGGITSV 223 Query: 444 EDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 E ++ + V GVM+GR A P+I ++ Sbjct: 224 EAGLDHLLM---VDGVMLGRAAYQDPYILHQ 251 >UniRef50_A2EN54 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 321 Score = 52.8 bits (121), Expect = 2e-05 Identities = 62/256 (24%), Positives = 108/256 (42%), Gaps = 16/256 (6%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308 L+P+ +G++ FR +C G DV M + ++ E + QI G Sbjct: 17 LAPMVEMGDIAFRILCHRHGCDVCWTGMINGSQWNRSKTYRQQQIEYSEEDRPLVIQISG 76 Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRCASKL 367 + + A+ + E ID+N+GC + K+G G M+ + V + Sbjct: 77 SIDVDLLTTAKSMSEFGVP--IDINLGC-CQKVAKRGEYGYFMVDSEQKRQNVVNLIKSI 133 Query: 368 ---LSIPFTVKMR-----TGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDW 419 +++P VK+R +G+ IT + GASLIT+HGRS + Sbjct: 134 PSEITVPLYVKIRALTDESGI-PSIPITVDFAKHLEEAGASLITIHGRSAAQDKHGPLNK 192 Query: 420 EYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQK 479 E ++ QA + PV NG I S +D M + + M + L+ P +F++ Q Sbjct: 193 ELVKAVVQAVS-IPVIVNGGINSLDDARNMIRETGAI-AAMSAQSLLMDPTLFDKNGRQP 250 Query: 480 IWDISSKDRFEILKKY 495 + + + +I +KY Sbjct: 251 N-TVFALEYLDIFEKY 265 >UniRef50_Q5ZVH8 Cluster: Zinc binding TIM barrel protein, YjbN family; n=4; Legionella pneumophila|Rep: Zinc binding TIM barrel protein, YjbN family - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 334 Score = 52.0 bits (119), Expect = 4e-05 Identities = 57/264 (21%), Positives = 108/264 (40%), Gaps = 16/264 (6%) Query: 245 NKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGA 304 +KL ++P+ N PFR + + + ++ + AL + E Sbjct: 11 SKLSIAPMIDWTNSPFRTLMRLLAPNALLYTEMQTTGAVQN-NPDRALYF-NSVEHPLAI 68 Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G + + K A ++ E + I+LN+GCP D + G+ +M + +R Sbjct: 69 QLGGADKSALVKCA-IIAEQKGFNEINLNLGCPSDKVQAGRFGACLMKEPEHVADCIRAI 127 Query: 365 SKLLSIPFTVKMRTGV-YQDK-KITHTIVPKMSNWGASLITVHGRS--------REARYT 414 +++ IP T K R G+ QD + + + G + +H R ++ R Sbjct: 128 KQVVGIPVTAKTRIGIDNQDSYEFFRSFSLHLVEAGCDKLIIHARKAWLNGLNPKQNRTI 187 Query: 415 KSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 +++Y+ + + NG+I + E E+ V GVM+GR A P+ E Sbjct: 188 PPVNYDYVYELKKEIPHIFITINGNILTVE---EINNHLKHVDGVMLGRLACDNPYQIAE 244 Query: 475 IKEQKIWDISSKDRFEILKKYSNY 498 I + + R ++L Y +Y Sbjct: 245 IHQALYPEFIKIKRSQLLMNYLDY 268 >UniRef50_A6GGZ7 Cluster: Putative uncharacterized protein; n=2; Bacteria|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 362 Score = 52.0 bits (119), Expect = 4e-05 Identities = 49/214 (22%), Positives = 90/214 (42%), Gaps = 16/214 (7%) Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334 EM C ++L G ++ ++ H +E Q+ G++P + A++ E D +++N+ Sbjct: 52 EMVTCPAVLHGDREH--ILGYHPSEHPLALQLGGDDPEALAACARIAAE-LGYDEVNINV 108 Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTI--VP 392 GCP D + G +M + V + + +P TVK R GV + + + V Sbjct: 109 GCPSDRVQSGNFGVCLMKDPARVRDCVVAMREAVELPVTVKHRIGVDELDRYEDMLHFVD 168 Query: 393 KMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444 ++ L TVH R ++ R + + A+ V NG + + Sbjct: 169 VVAAAEPDLFTVHARKAWLQGLSPKQNRNVPPLRYAEVHRLARERPGVFVEINGGFKTAD 228 Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQ 478 E + V VM+GR A PW+F + ++ Sbjct: 229 AIAEQLE---RVDAVMLGRAAWDDPWLFAAVDQR 259 >UniRef50_A1RNI1 Cluster: TIM-barrel protein, yjbN family; n=30; Bacteria|Rep: TIM-barrel protein, yjbN family - Shewanella sp. (strain W3-18-1) Length = 343 Score = 51.6 bits (118), Expect = 6e-05 Identities = 46/192 (23%), Positives = 84/192 (43%), Gaps = 14/192 (7%) Query: 296 HETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLP 355 ++ E Q+ G+NP + + A+L E D ++LN+GCP D + G+ +M Sbjct: 72 NQEEHPLALQLGGSNPQDLARCAKLAAERG-YDEVNLNVGCPSDRVQNGRFGACLMAEPE 130 Query: 356 ALETSVRCASKLLSIPFTVKMRTGV-YQDK-KITHTIVPKMSNWGASLITVHGRS----- 408 + V +++ IP TVK R G+ QD + + ++ G + T+H R Sbjct: 131 LVAECVDAMKQVVDIPVTVKTRIGIDEQDSYEFLTYFIDIVNAKGCTDFTIHARKAWLQG 190 Query: 409 ---REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465 +E R D+E + + + NG + + E + + + GVM+GR A Sbjct: 191 LSPKENREIPPLDYERVYQLKRDYPVLNISINGGVTTLE---QAQGHLAQLDGVMMGREA 247 Query: 466 LIKPWIFNEIKE 477 P+I + + Sbjct: 248 YQNPYILARVDQ 259 >UniRef50_Q6BX60 Cluster: Debaryomyces hansenii chromosome B of strain CBS767 of Debaryomyces hansenii; n=1; Debaryomyces hansenii|Rep: Debaryomyces hansenii chromosome B of strain CBS767 of Debaryomyces hansenii - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 374 Score = 51.6 bits (118), Expect = 6e-05 Identities = 60/257 (23%), Positives = 109/257 (42%), Gaps = 26/257 (10%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGAD------VTCGEMALCESLLKG-------LK 287 ++++ KL L+P+ G +P R + +GAD + ++ CE ++ L Sbjct: 2 VEYSGKLALAPMVRSGEIPTRLMALRYGADLVWTPEIVDKKLIKCERVINDDLGTVDFLD 61 Query: 288 QEWALVKRHETEDLFGA---QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKK 344 +V R + G QI +P + + A+++ + ++D IDLN GCP Sbjct: 62 PNKKVVFRTYPAEELGKLIFQIGSADPELAVQAAKIVAQ--DVDGIDLNCGCPKPFSTHS 119 Query: 345 GGGSGMMHRLPALETSVRC----ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGAS 400 G G+ ++ LE +R K+ IP + K+R D + ++ ++ G S Sbjct: 120 GMGAALLTTPDLLELILRNLVSEVGKVYDIPISAKIRLLDDTDVTPSLELIDRLCKTGIS 179 Query: 401 LITVHGRSREARYTKSSDWEYIETCAQA--ATPCPVYGNGDIFSYEDY-VEMRKIAPTVK 457 +T+H R+ R + +++ + A NG I S ++ + RK V Sbjct: 180 NLTLHCRTPRMRNRDTPVRDFLPSIIDTVHANNVSFIINGSIRSRREFHLLQRKYGEKVG 239 Query: 458 GVMIGRGALIKPWIFNE 474 G MI A P +F E Sbjct: 240 G-MIAESAESNPTVFAE 255 >UniRef50_A6RW05 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 278 Score = 51.6 bits (118), Expect = 6e-05 Identities = 42/145 (28%), Positives = 59/145 (40%), Gaps = 11/145 (7%) Query: 330 IDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHT 389 +D+N GCP G+ +MH+ + V+ A L R G K + T Sbjct: 63 VDINCGCPQSWACACSIGAALMHKRELVAEMVKEAKSALK-------RDGFEGKKTVRET 115 Query: 390 I--VPKMSNWGASLITVHGRSREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYV 447 I + + + G IT+HGR R + + E I+ T P NGDIF+ D Sbjct: 116 IDFINTVQDAGVDFITIHGRMRSTPSSHPVNLEAIKLLTTHTT-VPTLSNGDIFTLSDAF 174 Query: 448 EMRKIAPTVKGVMIGRGALIKPWIF 472 V GVM RG L P +F Sbjct: 175 H-HTSHTGVSGVMSARGLLENPALF 198 >UniRef50_O51243 Cluster: Putative uncharacterized protein BB0225; n=3; Borrelia burgdorferi group|Rep: Putative uncharacterized protein BB0225 - Borrelia burgdorferi (Lyme disease spirochete) Length = 335 Score = 51.2 bits (117), Expect = 8e-05 Identities = 61/280 (21%), Positives = 118/280 (42%), Gaps = 30/280 (10%) Query: 244 NNKLYLSPLTTVGNLPFRRICKEFGADVTC-GEMALCESLLKGLKQEWALVKRHETEDLF 302 N K+ ++P+ + + FR + + VT M +S++ G ++ +VK++ E Sbjct: 4 NRKISIAPMVNITDEHFRYLIRLLSKKVTLYTPMISAKSIIMGDVKK--IVKQNPLESPI 61 Query: 303 GAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVR 362 QI N+ K Q+L+++ D +LN+GCP I G+ +M + ++ Sbjct: 62 AIQIATNSKNDALKAIQILEKHFNFDEYNLNVGCPSLKIQNANCGACLMGNANQVGEILK 121 Query: 363 CASKLLSIPFTVKMRTGV------YQDKKITH--TIVPKMSNWGASLITVHGR------- 407 + + P ++K R G+ Y+++ + V +S++G VH R Sbjct: 122 TMKENTNKPISIKHRLGIRPLSSDYKNESYSEVKNFVKIISDFGIKNFIVHARIAILKGF 181 Query: 408 -SREARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGAL 466 + R E++ + + NG I + E +++K V VMIGR A Sbjct: 182 SPKNNRNIPKLRHEFVYKLKKENKNLFIEINGGINNSE---QIKKHLSFVDSVMIGRSAF 238 Query: 467 IKPWIFNEIKEQKIWD----ISSKD----RFEILKKYSNY 498 P+ + + + ++ KD E +K+Y NY Sbjct: 239 ENPYFIANASREFLNETDEILTRKDILMQMVEYIKEYENY 278 >UniRef50_Q0VPD7 Cluster: TIM-barrel protein, yjbN family; n=4; Bacteria|Rep: TIM-barrel protein, yjbN family - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 348 Score = 51.2 bits (117), Expect = 8e-05 Identities = 48/210 (22%), Positives = 90/210 (42%), Gaps = 16/210 (7%) Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334 EM + +++L G + + + ++ E Q+ G++P + + ++ + D I+LN+ Sbjct: 63 EMVVAQAILHGDRDRF--LDFNDEEHPVALQLGGSDPQQLAQATRIAGDYG-YDEINLNV 119 Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGV--YQDKKITHTIVP 392 GCP D + + G+ +M + V +++P TVK R G+ D + V Sbjct: 120 GCPSDRVQQGKIGAILMAEPELVARCVEAMQAEVTVPVTVKTRIGIDDQDDYDFLYRFVD 179 Query: 393 KMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444 +M G + +T+H R +E R ++ A + NG + + Sbjct: 180 RMEASGCTSLTIHARKAILSGLSPKENRDIPPLIYQRAYAIKHAFPHIEIILNGGVKTLN 239 Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 E+ + V GVMIGR A P+ E Sbjct: 240 ---EVHEHMGEVDGVMIGREAYQNPYFLAE 266 >UniRef50_A7DKP5 Cluster: Dihydrouridine synthase, DuS; n=2; Methylobacterium extorquens PA1|Rep: Dihydrouridine synthase, DuS - Methylobacterium extorquens PA1 Length = 354 Score = 50.8 bits (116), Expect = 1e-04 Identities = 48/187 (25%), Positives = 77/187 (41%), Gaps = 14/187 (7%) Query: 299 EDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALE 358 E Q+ G+NP + A++ + + I+LN+GCP D + G+ +M + Sbjct: 81 EQPLAVQLGGSNPDDLAAAARIAADFGYAE-INLNVGCPSDRVQDGRFGACLMREPGLVG 139 Query: 359 TSVRCASKLLSIPFTVKMRTGV-YQD-KKITHTIVPKMSNWGASLITVHGRS-------- 408 V + +P TVK R GV QD ++ + + G + VH R Sbjct: 140 ACVAALKAAVPVPVTVKCRLGVDDQDIEEALDAVADAVVAAGGDGLVVHARKAWLKGLSP 199 Query: 409 REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIK 468 RE R D+ + +A P+ NG I D + V GVMIGR A + Sbjct: 200 RENRDVPPLDYGRVARLKRAHPDLPIAVNGGI---ADIAAAKARLGEVDGVMIGRAAYTE 256 Query: 469 PWIFNEI 475 P + ++ Sbjct: 257 PALLLDV 263 >UniRef50_Q6C002 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 394 Score = 50.8 bits (116), Expect = 1e-04 Identities = 60/287 (20%), Positives = 120/287 (41%), Gaps = 35/287 (12%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLL----------------- 283 + + KL L+P+ G P R + ++GAD+ + + +L Sbjct: 2 VSYAGKLVLAPMVRSGEFPTRLLSIKYGADLVWSPEIVDKKMLECTREWNEKTKTVDFTV 61 Query: 284 ----KGLKQEWALVKR-HETE-DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCP 337 KG ++ A++ R E E D Q+ NP I +++ + ++ IDLN GCP Sbjct: 62 SQQGKGNTEKKAIIFRTSEAERDKIIFQVGSANPEIAVAACKMVAK--DVAGIDLNCGCP 119 Query: 338 IDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPF--TVKMRTGVYQDKKITHTIVPKMS 395 G G+ ++ L + K + PF ++ ++ + + ++ T +V +++ Sbjct: 120 KHFSMHAGMGAALLKTPDKLVAILEALVKEVGEPFNVSISVKIRLLETEEKTLELVDRLA 179 Query: 396 NWGASLITVHGRSREAR----YTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRK 451 G +T+H R+ R + + + E C + C V NGD+ + ++++ Sbjct: 180 QTGVKNLTIHCRTTPMRPREPVIRDTLAKVAEVCHKHGITCLV--NGDVEGRHELADLQE 237 Query: 452 IAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKYSNY 498 + G MI R A F + W +K+ +I ++Y N+ Sbjct: 238 -KYGIDGAMIARAAEANASCF-RAEGMLPWQQVTKEYLDICREYDNF 282 >UniRef50_A2EF32 Cluster: Dihydrouridine synthase, putative; n=1; Trichomonas vaginalis G3|Rep: Dihydrouridine synthase, putative - Trichomonas vaginalis G3 Length = 318 Score = 50.4 bits (115), Expect = 1e-04 Identities = 54/232 (23%), Positives = 89/232 (38%), Gaps = 9/232 (3%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALVKRHETEDLFGAQICG 308 L+P+ + +L +R + + G V M +G + + AQI G Sbjct: 22 LAPMAEISDLSWRMLIRNHGVKVCWTGMLNAHQWSQGSGYQNKFFNTCPEDHPLIAQIAG 81 Query: 309 NNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCASKL- 367 +N VA D +D+N+GC + + G M+ E ++ +L Sbjct: 82 SNEDQDLIVAAAKDLAKYADGVDVNLGCTQKIASRSEYGYFMVDNCQKREKTLELFRRLC 141 Query: 368 --LSIPFTVKMRTGVYQD----KKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEY 421 ++ P K+R + +KIT K+ G SL+ VHGR+ E Sbjct: 142 KEVNCPICAKIRIFIDDSGEVSEKITIDFAKKLEEAGVSLLQVHGRAEHRNKQADVYNEI 201 Query: 422 IETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFN 473 I+ QA PV NG I + ED + + GV + + L P F+ Sbjct: 202 IKHIVQAVN-IPVVANGGINTVEDAHKFME-ETGAAGVSVAQALLKDPTAFD 251 >UniRef50_A6RVN2 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 1174 Score = 50.4 bits (115), Expect = 1e-04 Identities = 35/112 (31%), Positives = 59/112 (52%), Gaps = 6/112 (5%) Query: 366 KLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS--SDWEYIE 423 K L +P T K+R + ++ T + + GAS++TVHGR+RE + K+ ++WE + Sbjct: 790 KELDVPVTAKIR--ILDTREKTLDYAKMVISAGASILTVHGRTREMKGHKTGLANWEMLR 847 Query: 424 TCAQA-ATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNE 474 ++ ++ NG+I + ED + K A GVM G L P IF++ Sbjct: 848 FLRESLPKEVVLFVNGNILAREDIDDCLK-ATGADGVMSAEGNLYDPTIFSD 898 >UniRef50_A6U9Y2 Cluster: Dihydrouridine synthase DuS; n=2; Sinorhizobium|Rep: Dihydrouridine synthase DuS - Sinorhizobium medicae WSM419 Length = 385 Score = 50.0 bits (114), Expect = 2e-04 Identities = 41/136 (30%), Positives = 68/136 (50%), Gaps = 7/136 (5%) Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334 EM + +++L+G + + L+ +E Q+ GN+P + + A++ E D I++N+ Sbjct: 51 EMIVADAVLRGDRAK--LLGHDASEHPVALQLGGNDPVKMAEAARI-GEAYGYDEINMNV 107 Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASK-LLSIPFTVKMRTGV-YQDKKIT-HTIV 391 GCP D + G+ +M PAL A K + IP TVK R GV QD ++ +V Sbjct: 108 GCPSDRVQSGTFGACLMQE-PALVADCIAAMKAAVEIPVTVKCRIGVDDQDPEVALRDLV 166 Query: 392 PKMSNWGASLITVHGR 407 + G + VH R Sbjct: 167 KCAKDAGTDGVWVHAR 182 >UniRef50_Q7R3H4 Cluster: GLP_158_49916_51304; n=1; Giardia lamblia ATCC 50803|Rep: GLP_158_49916_51304 - Giardia lamblia ATCC 50803 Length = 462 Score = 50.0 bits (114), Expect = 2e-04 Identities = 49/221 (22%), Positives = 98/221 (44%), Gaps = 17/221 (7%) Query: 249 LSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKGLKQEWALV---KRHETEDL-FGA 304 ++P+ LP+R + + +G ++ M +L+ K LV K E+ D Sbjct: 21 IAPMVDGSELPYRLLTRRYGVELAWTPMHSTNTLVTSSKAMTQLVDELKHGESIDRPLVL 80 Query: 305 QICGNNPYIITKVAQLLQENTE---LDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSV 361 Q+ GNNP L + D ++LN+GCP + + G+ +M L E + Sbjct: 81 QLSGNNPSNFELAYNTLVQMGAGCCFDVVELNMGCPQAVALRGKYGAYLMGHLDLAEEIL 140 Query: 362 R---CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKS-- 416 R + + V ++T + K T + ++ + G ++ T+HGR+R R + Sbjct: 141 RTLVAVTARSGLGHKVAVKTRLDISDKDTVKMCLRLCSTGIAMFTLHGRTRLQRTGSAVG 200 Query: 417 -SDWEYIETC---AQAATPCPV-YGNGDIFSYEDYVEMRKI 452 DW+ + + +A+ P + + NG +++ E + +R + Sbjct: 201 LPDWQALASILNNLRASYPHLIFFANGGVWNLETHEHLRSL 241 >UniRef50_A5GPV9 Cluster: TRNA-dihydrouridine synthase A; n=21; Cyanobacteria|Rep: TRNA-dihydrouridine synthase A - Synechococcus sp. (strain RCC307) Length = 335 Score = 49.2 bits (112), Expect = 3e-04 Identities = 56/243 (23%), Positives = 100/243 (41%), Gaps = 19/243 (7%) Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334 EM + ++L G +Q+ L+ E Q+ G++P ++ + A+L E D I+LN+ Sbjct: 45 EMVVAQALHHG-RQD-TLLGFDPLEKPIALQLGGDDPALLAEAAELA-ERWGYDEINLNV 101 Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTI--VP 392 GCP + K G+ +M + V +P TVK R G+ + + V Sbjct: 102 GCPSPKVKKGRFGACLMAEPQQVARCVEAMGAACRLPVTVKHRIGIDERDSYDELLDFVD 161 Query: 393 KMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444 ++ G VH R ++ R ++ + + V NG + E Sbjct: 162 TVAAAGCQRFAVHARKAWLEGLDPKQNRTVPPLRYDLVHALKRDRPALIVELNGGL---E 218 Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNEIKEQKIWDISSK--DRFEILKKYSNYGLEH 502 ++ V GVM+GR A P +N + ++ D ++ E+L+ + EH Sbjct: 219 SLSACQEQLHAVDGVMVGRAAYAHPLQWNRVDQEIFGDSNATPIKASEVLQGVLPHA-EH 277 Query: 503 WGS 505 W S Sbjct: 278 WCS 280 >UniRef50_Q7UBC5 Cluster: tRNA-dihydrouridine synthase A; n=231; Bacteria|Rep: tRNA-dihydrouridine synthase A - Shigella flexneri Length = 330 Score = 49.2 bits (112), Expect = 3e-04 Identities = 53/202 (26%), Positives = 87/202 (43%), Gaps = 16/202 (7%) Query: 297 ETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPA 356 E E Q+ G++P + + A+L E D I+LN+GCP D + G+ +M Sbjct: 61 EEEHPVALQLGGSDPAALAQCAKLA-EARGYDEINLNVGCPSDRVQNGMFGACLMGNAQL 119 Query: 357 LETSVRCASKLLSIPFTVKMRTGV-YQDK-KITHTIVPKMSNWG-ASLITVHGRS----- 408 + V+ ++SIP TVK R G+ QD + + +S G + +H R Sbjct: 120 VADCVKAMRDVVSIPVTVKTRIGIDDQDSYEFLCDFINTVSGKGECEMFIIHARKAWLSG 179 Query: 409 ---REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGA 465 +E R D+ + + + NG I S E E + + GVM+GR A Sbjct: 180 LSPKENREIPPLDYPRVYQLKRDFPHLTMSINGGIKSLE---EAKAHLQHMDGVMVGREA 236 Query: 466 LIKPWIFNEIKEQKIWDISSKD 487 P I + +++I+ S D Sbjct: 237 YQNPGILAAV-DREIFGSSDTD 257 >UniRef50_A7AWB5 Cluster: Dihydrouridine synthase (Dus) domain containing protein; n=1; Babesia bovis|Rep: Dihydrouridine synthase (Dus) domain containing protein - Babesia bovis Length = 362 Score = 47.2 bits (107), Expect = 0.001 Identities = 54/209 (25%), Positives = 89/209 (42%), Gaps = 18/209 (8%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKG-GGSGMMHRLPALETSVRC 363 Q+ GNN ++K + +F +LN+GCP + KG G+ +M+ P + V+ Sbjct: 78 QLGGNNLDSLSKAGNIALGYGYTEF-NLNVGCPSTRVSGKGCFGAALMNDAPLVGRIVKH 136 Query: 364 ASKLLSIPFTVKMRTGV-YQDK-KITHTIVPKMSNWGASLITVHGRS--------REARY 413 L P TVK R GV + D + + +++ G + VH R R+ R Sbjct: 137 LRSELGTPVTVKHRLGVDHNDSYEFVRDFISTVADQGCTDFIVHARKAWLNGINPRKNRS 196 Query: 414 TKSSDWEYIETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPW--- 470 D E + Q + NG I S E+ ++ V GVM+GR A P Sbjct: 197 IPPLDHERVYRLCQEFPNLNISINGGIKSLEEI--KYALSRGVYGVMVGRMAYENPCGLV 254 Query: 471 -IFNEIKEQKIWDISSKDRFEILKKYSNY 498 + +I + + K R +L+ Y+N+ Sbjct: 255 RVDTDIYGEATNPATCKTRRILLETYANF 283 >UniRef50_A4SY29 Cluster: Dihydrouridine synthase, DuS; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep: Dihydrouridine synthase, DuS - Polynucleobacter sp. QLW-P1DMWA-1 Length = 347 Score = 46.4 bits (105), Expect = 0.002 Identities = 30/112 (26%), Positives = 55/112 (49%), Gaps = 9/112 (8%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 Q+ G+ P + + A+L Q+ D IDLN GCP + + + G+ +M + V+ Sbjct: 53 QLGGSEPNDLARSAELAQQ-WGYDEIDLNCGCPSERVQRGAFGACLMAEPKLVADCVKAM 111 Query: 365 SKLLSIPFTVKMRTGV--------YQDKKITHTIVPKMSNWGASLITVHGRS 408 + IP +VK R G+ +D + + +++ GAS +T+H R+ Sbjct: 112 QNAVDIPISVKHRLGLDSMDAANSEKDYQFALDFIMAVADAGASQVTIHARN 163 >UniRef50_A3AVU4 Cluster: Putative uncharacterized protein; n=1; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 190 Score = 46.0 bits (104), Expect = 0.003 Identities = 19/44 (43%), Positives = 29/44 (65%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLK 284 +++ +KL L+P+ VG LPFR + E+GAD+T GE + LK Sbjct: 1 MEYRDKLVLAPMVRVGTLPFRLLAAEYGADITYGEEIIDHKFLK 44 Score = 37.1 bits (82), Expect = 1.3 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Query: 428 AATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 +A PV NGD+F YED+ + K A VM+ RGA+ IF Sbjct: 70 SALSIPVIANGDVFEYEDFKRI-KDATGAASVMVARGAMWNASIF 113 >UniRef50_P96192 Cluster: tRNA-dihydrouridine synthase C; n=1; Azotobacter vinelandii|Rep: tRNA-dihydrouridine synthase C - Azotobacter vinelandii Length = 309 Score = 45.6 bits (103), Expect = 0.004 Identities = 44/172 (25%), Positives = 74/172 (43%), Gaps = 7/172 (4%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGG-GSGMMHRLPALETSVRC 363 Q+ G++P + + A L E IDLN GCP +G G R + +S RC Sbjct: 68 QLLGSDPACLAENAALAAE-LGAPAIDLNFGCPAKTSTARGADGCCSTSRNCCMPSSARC 126 Query: 364 ASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYIE 423 A + GV + + + + G + + VH R++ Y + WE++ Sbjct: 127 AGPCRRCAGDRQDAPGV-RPARGRPGVRRALVEGGVAHLVVHARTKVEGYRPPASWEWLA 185 Query: 424 TCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 +A PVY N S + R+I+ V+ VM+G G + +P + +I Sbjct: 186 RVREAVA-VPVYANRK--SGRRRIGCREIS-GVEDVMLGCGLVSRPDLARQI 233 >UniRef50_A1AW94 Cluster: TIM-barrel protein, yjbN family; n=1; Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica)|Rep: TIM-barrel protein, yjbN family - Ruthia magnifica subsp. Calyptogena magnifica Length = 322 Score = 45.2 bits (102), Expect = 0.005 Identities = 44/211 (20%), Positives = 87/211 (41%), Gaps = 16/211 (7%) Query: 275 EMALCESLLKGLKQEWALVKRHETEDLFGAQICGNNPYIITKVAQLLQENTELDFIDLNI 334 EM ++L G K L+ + E Q+ G+ P + + A++ Q+ + I++N+ Sbjct: 36 EMVTARAILYGNKNR--LLDFNVCEHPLVLQLGGSEPKEMAQAAKIAQD-WGYNEININV 92 Query: 335 GCPIDLIYKKGGGSGMMHRLPALETSVRCASKLLSIPFTVKMRTGVYQDKKITHTI--VP 392 GCP + + G +M + V +++ +P TVK R GV + V Sbjct: 93 GCPSNRVQSSNFGVCLMQTPQVVAQCVDAMRQMVDVPITVKSRIGVDNMDSYDELVNFVA 152 Query: 393 KMSNWGASLITVHGRS--------REARYTKSSDWEYIETCAQAATPCPVYGNGDIFSYE 444 + + G + +H R +E R ++E + + + NG I E Sbjct: 153 TVESSGCDNLVIHARKAWLKGLSPKENRSVPKLNYERVYQIKRDFPHLAIGINGGIMDME 212 Query: 445 DYVEMRKIAPTVKGVMIGRGALIKPWIFNEI 475 ++ + V VM+GR +P++ ++ Sbjct: 213 SSLQHLE---HVDSVMLGRAVYHQPYLLRKV 240 >UniRef50_Q59YG4 Cluster: Potential tRNA dihydrouridine synthase; n=2; Saccharomycetales|Rep: Potential tRNA dihydrouridine synthase - Candida albicans (Yeast) Length = 433 Score = 45.2 bits (102), Expect = 0.005 Identities = 59/284 (20%), Positives = 120/284 (42%), Gaps = 33/284 (11%) Query: 241 IDWNNKLYLSPLTTVGNLPFRRICKEFGADVTCGEMALCESLLKG---LKQEWA----LV 293 I++ NKL L+P+ G LP R + +G D+ + + +L+ + QE +V Sbjct: 2 IEYANKLCLAPMVRSGELPIRLLSLRYGCDLLWTPELVDKKILQSTRIINQELNTIDYIV 61 Query: 294 KRHETED----LFGA----------QICGNNPYIITKVAQLLQENTELDFIDLNIGCPID 339 H+ D +F Q+ ++P + A+ + + ++D IDLN GCP + Sbjct: 62 SNHQQSDKKTVIFRKHPVETGRLILQLGSSDPQLAVDAARKVID--DVDGIDLNCGCPKN 119 Query: 340 LIYKKGGGSGMMHRLPALETSVRCASKLLSIP--FTVKMRTGVYQDKKITHTIVPKMSNW 397 G G+ ++ L + + + + IP ++ + ++ + + ++ K+ Sbjct: 120 FSTHSGMGAELLKTPDKLCSILINLVEKIGIPNKKSISCKIRLFNNYDQSKNLIEKILQT 179 Query: 398 GASLITVHGRSREARYTKSSDWEYIETCAQAATPCPV--YGNGDIFSYEDYVEMRKIAPT 455 G S +T+H R+ R + W ++ V NG++ + D ++ Sbjct: 180 GISNLTIHCRTPIMRNRQDPVWNFLPKLIPIIQTAGVNLVINGNMQNVADLKNLQSALND 239 Query: 456 VKG----VMIGRGALIKPWIFNEIKEQKIWDISSKDRFEILKKY 495 G +MI A P +F+ + + I ++ FEI +KY Sbjct: 240 NGGGKLSIMIAEAAEANPSVFSHSPKPQCLII--QELFEICQKY 281 >UniRef50_A2QES0 Cluster: Contig An02c0390, complete genome; n=12; Pezizomycotina|Rep: Contig An02c0390, complete genome - Aspergillus niger Length = 446 Score = 45.2 bits (102), Expect = 0.005 Identities = 43/175 (24%), Positives = 77/175 (44%), Gaps = 13/175 (7%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALETSVRCA 364 QI P I + A+L+ ++ ID+N GCP G G+ ++ L + Sbjct: 108 QIGTATPEIAVQAAKLVAG--DVAGIDVNSGCPKPFSTSGGMGAALLKTPDKLVAILEAL 165 Query: 365 SKLLSIPFT--VKMRTGVYQDKKITHTIVPKMSNWGASLITVHGRSREARYTKSSDWEYI 422 K + PF + ++ + +D + T +V ++ G + +TVH R+ R + + + + Sbjct: 166 VKEVGTPFQIGISVKIRILKDPEETRALVSRLVKTGITGLTVHCRTPPMRPRERAIRDQV 225 Query: 423 ----ETCAQAATPCPVYGNGDIFSY-EDYVEMRKIAPTVKGVMIGRGALIKPWIF 472 + C +A C + NGD+ S E + M++ V G MI A P F Sbjct: 226 RMIADICHEAGVACVI--NGDVTSKDEGHALMKEFG--VDGAMIATAAEANPSCF 276 >UniRef50_O51679 Cluster: Histidine phosphokinase/phophatase, putative; n=3; Borrelia burgdorferi group|Rep: Histidine phosphokinase/phophatase, putative - Borrelia burgdorferi (Lyme disease spirochete) Length = 335 Score = 44.8 bits (101), Expect = 0.007 Identities = 65/276 (23%), Positives = 117/276 (42%), Gaps = 27/276 (9%) Query: 247 LYLSPLTTVGNLPFRRICKEFGA-----DVTCGEMALCESLLKGLKQ--EWALVKRHETE 299 + L+P+ V + FR + G+ + E + +L G KQ + +K +E Sbjct: 18 MILAPMEDVTDTVFRNLIHLIGSAEGEPHIYFTEFISTKGILNGSKQSVQHVFLKPNELN 77 Query: 300 DLFGAQICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMMHRLPALET 359 AQI GN P + ++L + ID+N+GCP I KKG S +++ +L Sbjct: 78 RPLIAQIWGNVPEQFYRAIEILG-SMGFWGIDINMGCPKSKIIKKGVCSALINN-KSLAK 135 Query: 360 SVRCASK----LLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGR--SREARY 413 + ASK ++P +VK R G + + + ++TV+ R +++ Sbjct: 136 EIILASKEACARFNLPLSVKTRHGFSYPE--VDDWLGFLLGLEIDMLTVYPRLAVNQSKG 193 Query: 414 TKSSD--WEYIETCAQAATPCPVYGNGDIFSYED---YVEMRKIAPTVKGVMIGRGALIK 468 + D +E ++ + + GNGD+ S ++ YV+ + G+M GRG Sbjct: 194 PVNFDIFYELVKLRNNLSPSTLIIGNGDVLSLKEARYYVDKY----LIDGIMFGRGIFDN 249 Query: 469 PWIFNEIKEQKIWDISSKDRFEILKKYSNYGLEHWG 504 +F + + D + R ILK + WG Sbjct: 250 LNLFKPFSKHFL-DSNLNFRLNILKFHIKDFHATWG 284 >UniRef50_UPI000150A3F7 Cluster: hypothetical protein TTHERM_00141090; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00141090 - Tetrahymena thermophila SB210 Length = 1642 Score = 44.0 bits (99), Expect = 0.011 Identities = 48/199 (24%), Positives = 90/199 (45%), Gaps = 15/199 (7%) Query: 17 LQKSNII---EEKSYNLEKRKLDESSASFDDNNLEFKKTKIEITEDKNDSKTKKRGQN-K 72 +QKSNI EE S E +K A D+ ++ + +++I ++K +K N K Sbjct: 1230 IQKSNIFAIKEEVSVTQETQKTQPQKALVDNYIIDISQ-QVQINAQNQNNKEEKMNINDK 1288 Query: 73 SRPKIFKDGKESKPCPTILDVESSEQLKICQYNNCKFIHDSKQFL-NSKPKDIGDQCHVY 131 K +SK L+ E +Q K +N + I + Q N+ +D Q +Y Sbjct: 1289 LISKNESKENQSKSVDISLNNERKQQEK---HNISQIIIEKSQVTSNNINQDYIKQNQLY 1345 Query: 132 KVRGKCPRGIA-CRYGSDHITADGFNIVNREKFDQWKDDTKNTLQPSLQTQLQKKKYNFD 190 +++ + GI G + + F + K Q K D + Q S+ +Q+Q ++N Sbjct: 1346 EIKEESSVGIQNLNIGMNDVNKKDFQ---KNKIQQIKQDV-SVSQDSV-SQVQSIQFNIQ 1400 Query: 191 LAEKLVKHLDTRNKSVDKN 209 + ++++ L+ + K + KN Sbjct: 1401 VQQEVISQLEIQKKDIQKN 1419 >UniRef50_Q4PIC3 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 364 Score = 44.0 bits (99), Expect = 0.011 Identities = 47/185 (25%), Positives = 82/185 (44%), Gaps = 22/185 (11%) Query: 305 QICGNNPYIITKVAQLLQENTELDFIDLNIGCPIDLIYKKGGGSGMM--HRLPALETSVR 362 Q+ GNN + + A+ + D IDLN+GCP + G+ ++ P + V Sbjct: 91 QLAGNNVQQLVEAARRVAPYA--DAIDLNLGCPQRHAEQGHYGACLLPKQNWPLVAEIVS 148 Query: 363 CASKLLSIPFTVKMRTGVYQDKKITHTIVPKMSNWGASLITVHGR-SREARYTKS-SDWE 420 + + +P T K+R V K+ T + +++ G+SL+TVH R + AR K +D + Sbjct: 149 GMVQAVDVPITTKIRLPV--PKEQTAQLAVMLAHAGSSLVTVHPRFASSARRRKGLADLD 206 Query: 421 YI-------------ETCAQAATPCPVYGNGDIFSYEDYVEMRKIAPTVKGVMIGRGALI 467 + + Q V NG++ ++D V ++ GVM+G L Sbjct: 207 QVVKVREALQAQGLLRSAEQPHKDTAVVSNGNVQCWQDVVNNLELT-GASGVMVGETLLQ 265 Query: 468 KPWIF 472 P +F Sbjct: 266 NPALF 270 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.317 0.135 0.409 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 697,681,116 Number of Sequences: 1657284 Number of extensions: 31093427 Number of successful extensions: 101948 Number of sequences better than 10.0: 441 Number of HSP's better than 10.0 without gapping: 190 Number of HSP's successfully gapped in prelim test: 251 Number of HSP's that attempted gapping in prelim test: 100590 Number of HSP's gapped (non-prelim): 1032 length of query: 591 length of database: 575,637,011 effective HSP length: 105 effective length of query: 486 effective length of database: 401,622,191 effective search space: 195188384826 effective search space used: 195188384826 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 75 (34.3 bits)
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