Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001333-TA|BGIBMGA001333-PA|IPR002042|Uricase
(337 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q3HWK9 Cluster: Uricase; n=2; Endopterygota|Rep: Uricas... 715 0.0
UniRef50_UPI00015B5245 Cluster: PREDICTED: similar to uricase; n... 348 1e-94
UniRef50_Q17J02 Cluster: Uricase; n=1; Aedes aegypti|Rep: Uricas... 324 3e-87
UniRef50_P16163 Cluster: Uricase; n=7; Drosophila|Rep: Uricase -... 263 5e-69
UniRef50_A7SYI1 Cluster: Predicted protein; n=1; Nematostella ve... 249 7e-65
UniRef50_P25688 Cluster: Uricase; n=28; Deuterostomia|Rep: Urica... 237 2e-61
UniRef50_UPI0000E80A8A Cluster: PREDICTED: similar to urate oxid... 200 3e-50
UniRef50_A2SXR1 Cluster: Urate oxidase; n=1; Phytophthora parasi... 196 5e-49
UniRef50_O04420 Cluster: Uricase; n=32; Embryophyta|Rep: Uricase... 190 4e-47
UniRef50_Q1AS73 Cluster: Urate oxidase; n=1; Rubrobacter xylanop... 188 1e-46
UniRef50_Q54LT2 Cluster: Urate oxidase; n=1; Dictyostelium disco... 170 4e-41
UniRef50_A5NWT2 Cluster: Urate oxidase; n=1; Methylobacterium sp... 169 7e-41
UniRef50_Q9FVE2 Cluster: Urate oxidase II; n=1; Chlamydomonas re... 169 1e-40
UniRef50_Q0S841 Cluster: Urate oxidase; n=12; Actinomycetales|Re... 158 2e-37
UniRef50_A4FPC7 Cluster: Urate oxidase; n=2; Actinomycetales|Rep... 158 2e-37
UniRef50_Q82LJ2 Cluster: Putative uricase; n=2; Streptomyces|Rep... 153 6e-36
UniRef50_A2QG92 Cluster: Catalytic activity: Urate + O2 + H2O = ... 153 8e-36
UniRef50_O74409 Cluster: Probable uricase; n=1; Schizosaccharomy... 153 8e-36
UniRef50_A6REK6 Cluster: Uricase; n=9; Ascomycota|Rep: Uricase -... 152 1e-35
UniRef50_Q9RV70 Cluster: Uricase; n=2; Deinococcus|Rep: Uricase ... 149 8e-35
UniRef50_P78609 Cluster: Uricase; n=25; Ascomycota|Rep: Uricase ... 137 4e-31
UniRef50_Q75QK6 Cluster: Uricase; n=1; Aspergillus oryzae|Rep: U... 132 1e-29
UniRef50_Q4PGU1 Cluster: Putative uncharacterized protein; n=1; ... 117 5e-25
UniRef50_Q5KBI4 Cluster: Uricase (Urate oxidase), putative; n=1;... 116 1e-24
UniRef50_A5YRZ8 Cluster: Uricase; n=1; uncultured haloarchaeon|R... 76 2e-12
UniRef50_Q9KEU0 Cluster: Uricase; n=1; Bacillus halodurans|Rep: ... 69 1e-10
UniRef50_Q02C45 Cluster: Urate oxidase; n=1; Solibacter usitatus... 60 6e-08
UniRef50_O32141 Cluster: Uricase; n=3; Bacillus|Rep: Uricase - B... 58 2e-07
UniRef50_Q2SK85 Cluster: Predicted signal transduction protein c... 43 0.010
UniRef50_Q8EH11 Cluster: Outer membrane porin, putative; n=5; Sh... 36 2.0
UniRef50_A4IQ09 Cluster: Lantibiotic mersacidin transporter syst... 35 2.6
UniRef50_Q12W58 Cluster: Putative uncharacterized protein; n=1; ... 35 2.6
UniRef50_A6PT50 Cluster: Regulatory protein GntR, HTH; n=1; Vict... 35 3.5
UniRef50_UPI0000E49053 Cluster: PREDICTED: hypothetical protein;... 34 6.0
UniRef50_UPI0000499B79 Cluster: lipase; n=1; Entamoeba histolyti... 33 8.0
UniRef50_Q3DY25 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0
UniRef50_A7TI97 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0
UniRef50_Q8TJL7 Cluster: Predicted protein; n=1; Methanosarcina ... 33 8.0
UniRef50_O13682 Cluster: Helicase swr1; n=1; Schizosaccharomyces... 33 8.0
>UniRef50_Q3HWK9 Cluster: Uricase; n=2; Endopterygota|Rep: Uricase -
Bombyx mori (Silk moth)
Length = 337
Score = 715 bits (1768), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MPWTSTNRIYAKPSSTSANETPSPSLASPRVALTAAEDSGGRFELCDHGYGKSSVKLLHV 60
MPWTSTNRIYAKPSSTSANETPSPSLASPRVALTAAEDSGGRFELCDHGYGKSSVKLLHV
Sbjct: 1 MPWTSTNRIYAKPSSTSANETPSPSLASPRVALTAAEDSGGRFELCDHGYGKSSVKLLHV 60
Query: 61 HRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLLAKKYGVKTPEEFG 120
HRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLLAKKYGVKTPEEFG
Sbjct: 61 HRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLLAKKYGVKTPEEFG 120
Query: 121 AVVVNHFLYMYKQVLEAKCRVIEYPWERLQAGTPHSHAFVFSPIATRWSEVSQTRHEAVV 180
AVVVNHFLYMYKQVLEAKCRVIEYPWERLQAGTPHSHAFVFSPIATRWSEVSQTRHEAVV
Sbjct: 121 AVVVNHFLYMYKQVLEAKCRVIEYPWERLQAGTPHSHAFVFSPIATRWSEVSQTRHEAVV 180
Query: 181 VKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVEAEWIYDNMRTADFDNAWL 240
VKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVEAEWIYDNMRTADFDNAWL
Sbjct: 181 VKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVEAEWIYDNMRTADFDNAWL 240
Query: 241 TVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSEITWIKMTMPNKHYLNIDMSK 300
TVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSEITWIKMTMPNKHYLNIDMSK
Sbjct: 241 TVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSEITWIKMTMPNKHYLNIDMSK 300
Query: 301 FPVNVTKGDPRHFIYHPIDQPAGLIYAQLRRRPKSKL 337
FPVNVTKGDPRHFIYHPIDQPAGLIYAQLRRRPKSKL
Sbjct: 301 FPVNVTKGDPRHFIYHPIDQPAGLIYAQLRRRPKSKL 337
>UniRef50_UPI00015B5245 Cluster: PREDICTED: similar to uricase; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to uricase -
Nasonia vitripennis
Length = 387
Score = 348 bits (855), Expect = 1e-94
Identities = 163/305 (53%), Positives = 223/305 (73%), Gaps = 4/305 (1%)
Query: 30 RVALTAAEDSGGRFELCDHGYGKSSVKLLHVHRDEG-HHVIREFEVFTELKLASETAYIL 88
++ L E+S +FEL +GYGK++VKLL+V R+ H IRE+E+ L+L+++ Y++
Sbjct: 77 KIILKLLENSSDQFELGAYGYGKNNVKLLYVRRENALRHEIREYEIDVHLRLSTQKDYLV 136
Query: 89 GDNKEVVATDSQKNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWER 148
GDN++++ATDSQKNTVYL+AKK+GVK+PEEF ++ +HFLY Y+ V E RV EYPW R
Sbjct: 137 GDNRDIIATDSQKNTVYLMAKKHGVKSPEEFAIILCSHFLYQYRHVEEVNVRVEEYPWSR 196
Query: 149 LQA-GTPHSHAFVFSPIATRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYT 207
+ G H+HAFVF+P ATR+ +V+Q R+E+ ++ GL LRVLKTTQS+F DF+QD+Y
Sbjct: 197 HEVNGVSHNHAFVFTPTATRYCQVTQLRNESPRIRGGLKNLRVLKTTQSSFTDFIQDDYR 256
Query: 208 TLTDAVERIFSTIVEAEWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTL 267
TL DA +RIFST+V A W + DFD W TVK+ IL+ FAGPP +GVYSPSVQ+TL
Sbjct: 257 TLPDANDRIFSTVVTASWDFSTASGVDFDAVWRTVKNCILENFAGPPVSGVYSPSVQNTL 316
Query: 268 YQAEKTVLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYA 327
Y AE+ VL KV +I I+M MPNKHY +ID+SKF V + +Y P+D+P+G+IYA
Sbjct: 317 YLAERGVLSKVDQIFSIEMQMPNKHYFDIDLSKFSKLVPTENKE--VYLPMDKPSGIIYA 374
Query: 328 QLRRR 332
QL R+
Sbjct: 375 QLNRK 379
>UniRef50_Q17J02 Cluster: Uricase; n=1; Aedes aegypti|Rep: Uricase -
Aedes aegypti (Yellowfever mosquito)
Length = 325
Score = 324 bits (795), Expect = 3e-87
Identities = 162/310 (52%), Positives = 218/310 (70%), Gaps = 11/310 (3%)
Query: 38 DSGGRFELCDHGYGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVAT 97
D +++ ++GYGK SVK+LHV R+ H I+EFEV T+LKLAS+ Y+ GDN ++VAT
Sbjct: 17 DVPDHYKISNYGYGKDSVKVLHVMRNGLVHSIKEFEVGTKLKLASQKDYLQGDNSDIVAT 76
Query: 98 DSQKNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQAGTP--- 154
DSQKNTVYLLA+K+G+K+PEEFG ++ +HFL Y V E + EYPW R+ G
Sbjct: 77 DSQKNTVYLLARKHGLKSPEEFGILLCDHFLNKYSHVNEVSIHIDEYPWSRMGFGKGPYQ 136
Query: 155 --HSHAFVFSPIATRWSEVSQTRHEAV-VVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTD 211
H+HAFVF+P A R+ +V+Q R +++ V SGLS LRVLKTTQSAFV+FV DEY +L D
Sbjct: 137 DLHNHAFVFTPTAIRYCDVTQKRGDSMPTVISGLSDLRVLKTTQSAFVNFVNDEYRSLPD 196
Query: 212 AVERIFSTIVEAEWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAE 271
+RIFST++ + W + ++ DFD W VK IL+ FAG + G++SPSVQ+TLY AE
Sbjct: 197 QHDRIFSTVIRSSWQFSSVAGVDFDFCWNKVKQCILNTFAGETEKGIFSPSVQNTLYLAE 256
Query: 272 KTVLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGD--PRHFIYHPIDQPAGLIYAQL 329
K VLE + E++ I MTMPNKHY N D SKFP + +G+ ++ P+D+PAG+IYAQL
Sbjct: 257 KLVLESIPEVSSIDMTMPNKHYFNFDFSKFP-KLVQGEELKEETVFLPVDKPAGIIYAQL 315
Query: 330 RRR--PKSKL 337
R+ KSKL
Sbjct: 316 DRKKVTKSKL 325
>UniRef50_P16163 Cluster: Uricase; n=7; Drosophila|Rep: Uricase -
Drosophila melanogaster (Fruit fly)
Length = 352
Score = 263 bits (644), Expect = 5e-69
Identities = 139/318 (43%), Positives = 198/318 (62%), Gaps = 29/318 (9%)
Query: 42 RFELCDHGYGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQK 101
++E+ DHGYGK +VK+LHV R+ H I+EFEV T LKL S+ Y G+N ++VATDSQK
Sbjct: 31 QYEITDHGYGKDAVKVLHVSRNGPVHAIQEFEVGTHLKLYSKKDYYQGNNSDIVATDSQK 90
Query: 102 NTVYLLAKKYGVKTPEEFGAVVVNHFL---------------YMYKQVLEAKCRVI---- 142
NTVYLLAKK+G+++PE+F ++ HF+ Y +++V + + R
Sbjct: 91 NTVYLLAKKHGIESPEKFALLLARHFINKYSHVEEAHVHVEAYPWQRVCQEETRTNVNGK 150
Query: 143 -------EYPWERLQAGTPHSHAFVFSPIATRWSEVSQTRHEAV-VVKSGLSGLRVLKTT 194
+ + + H+HAF+F+P A + +V R + V +G+ GLRVLKTT
Sbjct: 151 CENGVQGNCDFSSIDNRSLHNHAFIFTPTALHYCDVVIRRTDPKQTVITGIKGLRVLKTT 210
Query: 195 QSAFVDFVQDEYTTLTDAVERIFSTIVEAEWIYDNMRTADFDNAWLTVKDAILDKFAGPP 254
QS+FV+FV DE+ +L D +RIFST+V+ W Y + DF AW TVK+ I+ FAG P
Sbjct: 211 QSSFVNFVNDEFRSLPDQYDRIFSTVVDCSWEYSDTENLDFLRAWQTVKNIIIRNFAGDP 270
Query: 255 DTGVYSPSVQHTLYQAEKTVLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFI 314
GV SPSVQHTLY +E+ VL+ + +++ I MTMPNKHY N D F + GD + +
Sbjct: 271 QVGVSSPSVQHTLYLSERQVLDVLPQVSVISMTMPNKHYFNFDTKPFQ-KIAPGD-NNEV 328
Query: 315 YHPIDQPAGLIYAQLRRR 332
+ P+D+P G IYAQL R+
Sbjct: 329 FIPVDKPHGTIYAQLARK 346
>UniRef50_A7SYI1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 297
Score = 249 bits (610), Expect = 7e-65
Identities = 128/291 (43%), Positives = 188/291 (64%), Gaps = 7/291 (2%)
Query: 49 GYGKSSVKLLHVHRDEG-HHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLL 107
GYGK+ V+LL + R +H I+E EV ELKL S+ Y+ GDN +V+ TD+QKNT+Y L
Sbjct: 12 GYGKTGVRLLKIKRRSTLYHEIKELEVAVELKLRSKKDYLNGDNSDVIPTDTQKNTIYAL 71
Query: 108 AKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERL-QAGTPHSHAFVFSPIAT 166
AKK+ + + EEFG V +FL +K V + E PW+R+ Q G H+HAF+ +P
Sbjct: 72 AKKHPLDSIEEFGLHVCKYFLDTHKHVDAVVIYINEAPWQRVKQGGIGHAHAFIMTPDVQ 131
Query: 167 RWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVEAEWI 226
R+ EVS R + V GL ++VLKTTQS F F++D+YT+L + +R F T+V ++
Sbjct: 132 RFCEVSHVRGDEPKVFGGLRDMKVLKTTQSGFTGFLKDQYTSLPEVGDRCFCTVVYCKYN 191
Query: 227 YDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSEITWIKM 286
+D++ DF+ VKD I++ F+GP TG YS SVQ+T+Y AE ++LEK+ +I I+M
Sbjct: 192 FDSLAGVDFNAVHKLVKDVIIEDFSGPAKTGEYSASVQNTMYIAENSLLEKIPQIGNIEM 251
Query: 287 TMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRRRPKSKL 337
MPN HY N++M F + K D + I P+D+P+G+I A L R+PK++L
Sbjct: 252 VMPNVHYFNVNMDAFGI---KND--NEILMPVDKPSGIIKAGLSRQPKARL 297
>UniRef50_P25688 Cluster: Uricase; n=28; Deuterostomia|Rep: Uricase
- Mus musculus (Mouse)
Length = 303
Score = 237 bits (581), Expect = 2e-61
Identities = 121/290 (41%), Positives = 175/290 (60%), Gaps = 7/290 (2%)
Query: 49 GYGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLLA 108
GYGK VK+LH+ RD +H I+E +L L S+ Y+ GDN +++ TD+ KNTV++LA
Sbjct: 20 GYGKDMVKVLHIQRDGKYHSIKEVATSVQLTLRSKKDYLHGDNSDIIPTDTIKNTVHVLA 79
Query: 109 KKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQA-GTPHSHAFVFSPIATR 167
K G++ E F + HFL + V A V E PW+R + G H HAF+ +P T
Sbjct: 80 KLRGIRNIETFAMNICEHFLSSFNHVTRAHVYVEEVPWKRFEKNGIKHVHAFIHTPTGTH 139
Query: 168 WSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVEAEWIY 227
+ EV Q R+ V+ SG+ L+VLKTTQS F F++D++TTL + +R F+T V +W Y
Sbjct: 140 FCEVEQMRNGPPVIHSGIKDLKVLKTTQSGFEGFLKDQFTTLPEVKDRCFATQVYCKWRY 199
Query: 228 DNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSEITWIKMT 287
R DF+ W V+D +L KFAGP D G YSPSVQ TLY + L ++ EI ++++
Sbjct: 200 QR-RDVDFEAIWGAVRDIVLQKFAGPYDKGEYSPSVQKTLYDIQVLSLSQLPEIEDMEIS 258
Query: 288 MPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRRRPKSKL 337
+PN HY NIDMSK + + K + + P+D P G I ++R+ S+L
Sbjct: 259 LPNIHYFNIDMSKMGL-INKEE----VLLPLDNPYGKITGTVKRKLPSRL 303
>UniRef50_UPI0000E80A8A Cluster: PREDICTED: similar to urate oxidase
(EC 1.7.3.3); n=2; Gallus gallus|Rep: PREDICTED: similar
to urate oxidase (EC 1.7.3.3) - Gallus gallus
Length = 320
Score = 200 bits (489), Expect = 3e-50
Identities = 99/256 (38%), Positives = 151/256 (58%), Gaps = 1/256 (0%)
Query: 44 ELCDHGYGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNT 103
E+ + YGK+++K L +HR+ H ++E EV T L+L S Y+ G+N V+ TD+ KN
Sbjct: 22 EVLNCEYGKNTIKFLRLHREGKKHFVKEVEVCTHLRLTSAHEYLDGNNSFVIPTDTIKNI 81
Query: 104 VYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWER-LQAGTPHSHAFVFS 162
V +LAKK G+ + E+F + HF+ + QV K + E PW+R Q G PH H+F+
Sbjct: 82 VLVLAKKNGISSIEQFAIDICKHFMTTFCQVAYVKTYIQEVPWQRQYQNGVPHIHSFILV 141
Query: 163 PIATRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVE 222
P R+ E Q R+ +VV +G+ L+++KTTQS F F ++E+TTL + +RI
Sbjct: 142 PDGIRFCEAEQCRNGPLVVCAGIKDLKLMKTTQSGFEGFYRNEHTTLPERNDRILCGEFF 201
Query: 223 AEWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSEIT 282
+W Y R DFD W V++ IL+ F+GPPD G YSPS Q T+ + VL +V ++
Sbjct: 202 CKWSYGECRDFDFDCIWSKVRECILEAFSGPPDCGEYSPSYQRTVNCIQMCVLSRVPQVQ 261
Query: 283 WIKMTMPNKHYLNIDM 298
I++ + N Y +DM
Sbjct: 262 VIEVILNNNFYNVVDM 277
>UniRef50_A2SXR1 Cluster: Urate oxidase; n=1; Phytophthora
parasitica|Rep: Urate oxidase - Phytophthora parasitica
(Potato buckeye rot agent)
Length = 307
Score = 196 bits (479), Expect = 5e-49
Identities = 123/302 (40%), Positives = 177/302 (58%), Gaps = 17/302 (5%)
Query: 44 ELCDHGYGKSSVKLLHVHRD-EGHHVIR-EFEVFTELKLASETAYILGDNKEVVATDSQK 101
+L H +GK V++L V R E H VI+ E EV E A+ +AY GDN V+ TDS K
Sbjct: 4 KLLQHEHGKGRVRMLKVTRTPEKHSVIQLEAEVLLEGAPAA-SAYYDGDNGRVLPTDSVK 62
Query: 102 NTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLE-AKCRVIEYPWERLQAGT------P 154
NTV++LAKK+ + E+FG ++ HF+ + ++ AK ++ E PW+R+ P
Sbjct: 63 NTVWVLAKKHEFASLEDFGVILAKHFVTKHPDIISVAKVKLFETPWQRVVVPDSKGKTRP 122
Query: 155 HSHAFVF-SP-IATRWSEVSQTRHEA--VVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLT 210
H HAFV SP +T + ++ + A V V+ G+ GL+VLKTTQS+FVDF +D++TTL
Sbjct: 123 HHHAFVSASPGFSTAYVVARKSAYGAPDVTVQGGVDGLKVLKTTQSSFVDFFRDDFTTLP 182
Query: 211 DAVERIFSTIVEAEWIYD-NMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQ 269
D +R+ T V A W Y + DF +K+ +L+ FAGP D GV SP+VQ TLY+
Sbjct: 183 DVPDRLVCTCVTATWSYTPDAIGGDFVARVAEIKNVLLETFAGPADVGVSSPAVQFTLYK 242
Query: 270 AEKTVLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQL 329
+ VLEK + IK+TMPN H ID+S+F P ++ P D+P G+I A +
Sbjct: 243 MGEAVLEKCPYVKDIKITMPNIHNNPIDLSRF--GCKNIHPHGEVFLPTDEPHGIISATM 300
Query: 330 RR 331
R
Sbjct: 301 VR 302
>UniRef50_O04420 Cluster: Uricase; n=32; Embryophyta|Rep: Uricase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 309
Score = 190 bits (463), Expect = 4e-47
Identities = 116/306 (37%), Positives = 164/306 (53%), Gaps = 12/306 (3%)
Query: 35 AAEDSGGRFELCDHGYGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEV 94
A E G R E HG + V + H +G H E+ V L ++Y L DN ++
Sbjct: 2 AQEADGIRLEQ-RHGKARVRVGRVWRHAHDGSHHFVEWNVSISLLSHCLSSYRLDDNSDI 60
Query: 95 VATDSQKNTVYLLAKKYGVK-TPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQA-G 152
VATD+ KNTVY+ AK+ G + + EEF ++ HF Y QV A +IE PWER+ G
Sbjct: 61 VATDTIKNTVYVKAKECGDRLSVEEFAILIGKHFCSFYPQVFTAIVNIIEKPWERVSIDG 120
Query: 153 TPHSHAFVFSPIATRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDA 212
PH H F +E + A+ + SG+ GL +LKTTQS F FV+D+YT L +
Sbjct: 121 KPHLHGFKLGS-ENHTTEARVEKSGALNLTSGIGGLALLKTTQSGFERFVRDKYTILPET 179
Query: 213 VERIFSTIVEAEWIYDNMRTAD-------FDNAWLTVKDAILDKFAGPPDTGVYSPSVQH 265
ER+ +T V A W Y A F ++ VK ++D F GPP+TGVYSPSVQ
Sbjct: 180 RERMLATEVNASWRYSYESVASIPTKGLYFSEKFMDVKKVLMDTFFGPPETGVYSPSVQR 239
Query: 266 TLYQAEKTVLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLI 325
TLY VL++ ++++ I + MPN H+L +++S N + + +Y P D+P G I
Sbjct: 240 TLYLMGSAVLKRFADVSSIHLKMPNIHFLPVNLST-KENPSMVKFKDDVYLPTDEPHGSI 298
Query: 326 YAQLRR 331
A L R
Sbjct: 299 EATLSR 304
>UniRef50_Q1AS73 Cluster: Urate oxidase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Urate oxidase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 294
Score = 188 bits (459), Expect = 1e-46
Identities = 107/299 (35%), Positives = 163/299 (54%), Gaps = 12/299 (4%)
Query: 34 TAAEDSGGRFELCDHGYGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKE 93
TA++ SG R L YGKS ++L+ V R+ G H I+E V + A++ GDN
Sbjct: 4 TASKTSGRRIVLGHTNYGKSDIRLVKVFRNPGRHEIKELRVDVSQEGDFAAAHVEGDNTG 63
Query: 94 VVATDSQKNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQA-G 152
++ATD+ +NTVY LA+ + E FG +V HFL + + ++E+ WER++A G
Sbjct: 64 LMATDTMRNTVYALARDRLTGSAEAFGVELVRHFLEAAPRANRVRVSMVEHLWERIEAGG 123
Query: 153 TPHSHAFVFSPIATRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDA 212
PH H+FV R +EV V++G+ L VLKTT S + F++D +TTL +
Sbjct: 124 KPHEHSFV-RAAGERTAEVVGDEEGNFSVEAGIDDLLVLKTTNSGWAGFLRDRFTTLPET 182
Query: 213 VERIFSTIVEAEWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEK 272
+RI ST+V + W Y DFD W ++ IL+ F T YSPSVQ TL++ +
Sbjct: 183 DDRILSTVVTSRWSYGGATDLDFDRLWEGIRRRILETF-----TDHYSPSVQFTLHRMGR 237
Query: 273 TVLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRR 331
VLE E+ I ++PN+H+L D+ +F + G+ ++H +P GLI + R
Sbjct: 238 AVLESFPEVERIHFSLPNRHHLLYDLERFGME-NPGE----VFHADAEPYGLIEGTVER 291
>UniRef50_Q54LT2 Cluster: Urate oxidase; n=1; Dictyostelium
discoideum AX4|Rep: Urate oxidase - Dictyostelium
discoideum AX4
Length = 287
Score = 170 bits (414), Expect = 4e-41
Identities = 100/291 (34%), Positives = 163/291 (56%), Gaps = 16/291 (5%)
Query: 45 LCDHGYGKSSVKLLHVHRDEG-HHVIREFEVFTELKLA--SETAYILGDNKEVVATDSQK 101
L D+ YGK+ V++L V + +H + +F+ L+ A SET Y+ GDN +VVATD+ K
Sbjct: 4 LIDNRYGKARVRVLRVFKGPNEYHKVFDFDCRVLLRGAEFSET-YLTGDNSKVVATDTMK 62
Query: 102 NTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQAGTPHSHAFVF 161
NTVY++A+K K+ EE+G ++ HFL Y V + + E W R++ A F
Sbjct: 63 NTVYVIAQKEEFKSLEEYGILLGKHFLATYSWVNGVEVVMRENQWRRIKTSNGKEQAHSF 122
Query: 162 SPIATRWS-EVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTI 220
S V+ +R ++ VV SG+ L ++KTTQS F F +D+YT+L + +R+F+T+
Sbjct: 123 QRDREIHSVTVTSSRDKSPVVVSGIDDLLIMKTTQSGFEGFHRDKYTSLKETKDRVFATV 182
Query: 221 VEAEWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSE 280
V A W Y N + D+ + K ++ D FA YS SVQ TL+ K V+ KV +
Sbjct: 183 VTANWTY-NTLSVDYSKVFEQFKLSVFDIFA-----QTYSRSVQETLFLIAKDVISKVPQ 236
Query: 281 ITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRR 331
+ + +++PNKH D S+ + + ++ P+++P+GLI ++R
Sbjct: 237 VEQVHLSLPNKHAFGFDFSRLNI-----ENNQTVFQPVEEPSGLIEGTIKR 282
>UniRef50_A5NWT2 Cluster: Urate oxidase; n=1; Methylobacterium sp.
4-46|Rep: Urate oxidase - Methylobacterium sp. 4-46
Length = 279
Score = 169 bits (412), Expect = 7e-41
Identities = 99/283 (34%), Positives = 149/283 (52%), Gaps = 12/283 (4%)
Query: 50 YGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLLAK 109
YGK V+++ VHRD H +RE V L + A+ DN V+TD+ KN V ++A+
Sbjct: 8 YGKGRVRVMRVHRDGARHEVRELTVQAMLTGGFDPAFTRADNSTTVSTDTVKNVVNIVAR 67
Query: 110 KYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQA-GTPHSHAFVFSPIATRW 168
+ PEEF V + Y V A E W RL G PH HAF T
Sbjct: 68 ESMTLAPEEFCRAVARRLIDAYAMVETATVTAHETRWSRLAVDGEPHPHAFTLDGNGTSV 127
Query: 169 SEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVEAEWIYD 228
++V+ R A+ ++SGLSG LKTT+S + ++V+D YTTL++ +R+ +T +EA W++
Sbjct: 128 AKVTMARGGALTIESGLSGFTFLKTTESGWANYVKDPYTTLSETHDRLAATSMEASWLW- 186
Query: 229 NMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSEITWIKMTM 288
AD+ A + D++L FA YS S+Q +LY+ + L V EI I M
Sbjct: 187 GRPPADYPAANARILDSLLKVFA-----TTYSHSIQDSLYRMGRAALAAVPEIETISMAC 241
Query: 289 PNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRR 331
PNKHYL +D+++F + D + ++ D+P G I + R
Sbjct: 242 PNKHYLLVDLARFGL-----DNDNQVFVATDEPHGQIECTVGR 279
>UniRef50_Q9FVE2 Cluster: Urate oxidase II; n=1; Chlamydomonas
reinhardtii|Rep: Urate oxidase II - Chlamydomonas
reinhardtii
Length = 295
Score = 169 bits (410), Expect = 1e-40
Identities = 101/287 (35%), Positives = 150/287 (52%), Gaps = 10/287 (3%)
Query: 48 HGYGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLL 107
H +GKS V+L V RD H + E+ V T + E A++ GDN + ATD+QKNTVY++
Sbjct: 9 HHHGKSKVRLGRVWRDGTVHHMVEWNVNTMIDSDMEHAFLNGDNTGMTATDTQKNTVYVV 68
Query: 108 AKKYGVK-TPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQ-AGTPHSHAFVFSPIA 165
A++ K T E++ + HF+ Y V +AK V + PW R+Q +G PH H F
Sbjct: 69 AQRMSQKCTIEQYAIALAQHFVRTYPLVSKAKIYVEQKPWTRVQQSGLPHDHGFALQGTE 128
Query: 166 TRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVEAEW 225
R V+ + + V +GL L +LKTTQS + F++D+YT L + +RI ++ V W
Sbjct: 129 VRTVYVTYDKAGTLDVTAGLKDLSLLKTTQSGYEGFLRDQYTLLPETNDRIMASTVTCTW 188
Query: 226 IYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSEITWIK 285
Y A +D A+ K +LD F GP PSVQ+TLY K +L++V I
Sbjct: 189 KY-AAAPACYDAAYAAAKQGLLDAFLGPGARRRVQPSVQYTLYDMAKNILDRVPTSESIF 247
Query: 286 MTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRRR 332
+ MPN H++ P N + +Y +P G I A + R+
Sbjct: 248 LNMPNLHFI-------PCNPVGSSFNNDVYVATSEPHGNIEAVITRK 287
>UniRef50_Q0S841 Cluster: Urate oxidase; n=12; Actinomycetales|Rep:
Urate oxidase - Rhodococcus sp. (strain RHA1)
Length = 303
Score = 158 bits (383), Expect = 2e-37
Identities = 91/295 (30%), Positives = 158/295 (53%), Gaps = 13/295 (4%)
Query: 38 DSGGRFELCDHGYGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVAT 97
D G L DH YGK+ +++ ++RD H IR+ V T L+ A++ GD V+ T
Sbjct: 3 DLTGAIVLGDHQYGKAENRIVRIYRDTPRHEIRDVSVSTCLRGDFSAAHLAGDQSSVLPT 62
Query: 98 DSQKNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWER-LQAGTPHS 156
D+QK T + AK+ G+ + EE+G + HF+ V A+ + EY W+R + G H
Sbjct: 63 DTQKQTAFSYAKEKGLDSIEEYGLTLARHFVDDVAPVEGARIEIEEYAWQRAVVDGAEHD 122
Query: 157 HAFVFSPIATRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERI 216
H +V R + ++ + V GL L +LK+T S F F++DEYT L + +R+
Sbjct: 123 HTWVRKGEEVRTAAIT-VDGDGTWVVGGLKDLVILKSTGSEFFGFLKDEYTILEETHDRV 181
Query: 217 FSTIVEAEWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLE 276
+T + +W + D++ + +K+ I+ FA V+S ++Q TLY+ K +LE
Sbjct: 182 MATSLVVQWRFVT-TDVDWNGVYAGIKERIVATFA-----TVHSLALQQTLYEIGKAILE 235
Query: 277 KVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRR 331
+ + ++++ PNKH+ D+++F V + + ++H D+P GLI A ++R
Sbjct: 236 RYPVLAEVRLSAPNKHHFAHDLARFGV-----ENDNEVFHAADRPYGLIQATVQR 285
>UniRef50_A4FPC7 Cluster: Urate oxidase; n=2; Actinomycetales|Rep:
Urate oxidase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 296
Score = 158 bits (383), Expect = 2e-37
Identities = 93/283 (32%), Positives = 157/283 (55%), Gaps = 13/283 (4%)
Query: 50 YGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLLAK 109
YGK+ V+++ V++D H I++ V T L+ + ++ GDN + TD+QKNTVY AK
Sbjct: 10 YGKAEVRIVSVNKDTPRHTIKDLNVSTSLRGDLDAVHLTGDNSNCLPTDTQKNTVYAFAK 69
Query: 110 KYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQ-AGTPHSHAFVFSPIATRW 168
+ + E+F + HF+ + + A+ + EY WER+ GT H H+F S R
Sbjct: 70 EAPIGEIEDFALRLGRHFVNTAEGITGARILIDEYSWERIPVGGTGHDHSFARSTDEKRT 129
Query: 169 SEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVEAEWIYD 228
+ V+ +A VV SGL L VLK+T S F + +D+YTTL + +RI +T V A W Y
Sbjct: 130 TAVTIDGDKAHVV-SGLKDLVVLKSTGSEFWGYPKDKYTTLAETDDRILATAVTARWRYL 188
Query: 229 NMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSEITWIKMTM 288
D+ ++ +V+ +L+ FA +S ++Q +LY+ K VL+ E+ +++++
Sbjct: 189 G-TDLDWGKSFESVRATMLEAFA-----TTHSLALQQSLYEMGKQVLDAHPEVAEVRLSL 242
Query: 289 PNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRR 331
PNKH+ +D+ F + D + +++ D+P GLI + R
Sbjct: 243 PNKHHFLVDLKPFGL-----DNDNEVFYAADRPYGLIEGTVLR 280
>UniRef50_Q82LJ2 Cluster: Putative uricase; n=2; Streptomyces|Rep:
Putative uricase - Streptomyces avermitilis
Length = 315
Score = 153 bits (371), Expect = 6e-36
Identities = 94/295 (31%), Positives = 157/295 (53%), Gaps = 24/295 (8%)
Query: 50 YGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLLAK 109
YGK+ +++ + RD H I++ V L + + G N V+ TD+ KNTVY AK
Sbjct: 18 YGKAENRVVKITRDGATHHIKDLNVSVALSGDMDEVHYSGSNANVLPTDTTKNTVYAFAK 77
Query: 110 KYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQAGTPHS---------HAFV 160
++G+++ E+FG + HF+ + + A+ R+ EY WER++A +S H+FV
Sbjct: 78 EHGIESAEQFGIHLARHFVTSQEPIKTARIRIEEYTWERIEASDANSRFIGADEVKHSFV 137
Query: 161 FSPIATRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTI 220
TR ++++ V+ SGL L V+ +T S F +V+D+YTTL +A +RI +T
Sbjct: 138 RKGQETRVTQITYDGSSWEVI-SGLKDLVVMNSTNSEFWGYVKDKYTTLPEAYDRILATQ 196
Query: 221 VEAEWIY----DNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLE 276
V A W + D + ++ ++ + +L FA YS S+Q TLYQ ++
Sbjct: 197 VAARWRFNWSDDERKMPHWEKSYEQTRKHMLQAFA-----ETYSLSLQQTLYQMGSRIIN 251
Query: 277 KVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRR 331
SEI ++ ++PNKH+ +D+ F + K D + +Y D+P GLI A + R
Sbjct: 252 HRSEIDEVRFSLPNKHHFLVDLEPFGL---KND--NEVYFAADRPYGLIEATVLR 301
>UniRef50_A2QG92 Cluster: Catalytic activity: Urate + O2 + H2O =
5-hydroxyisourate + H(2)O(2); n=3; Pezizomycotina|Rep:
Catalytic activity: Urate + O2 + H2O = 5-hydroxyisourate
+ H(2)O(2) - Aspergillus niger
Length = 306
Score = 153 bits (370), Expect = 8e-36
Identities = 100/300 (33%), Positives = 152/300 (50%), Gaps = 17/300 (5%)
Query: 43 FELCDHGYGKSSVKLLHVHRDEGHHV--IREFEVFTELKLASETAYILGDNKEVVATDSQ 100
+ L D YGK +V+L VHRD G V + E V L+ ET+Y DN +V TD+
Sbjct: 2 YNLSDAQYGKDNVRLYKVHRDAGTGVQTVYELTVCVLLEGDIETSYTKEDNSVLVTTDAI 61
Query: 101 KNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQ-AGTPHSHAF 159
KNT Y++AK V PE FG+++ HF+ YK + A + + WER+ PH H+F
Sbjct: 62 KNTCYIVAKHNPVHPPELFGSILGKHFITQYKHIHTAHIDITCHTWERMTIENEPHPHSF 121
Query: 160 VFSPIATRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFST 219
R V ++ + + S + GL VLK+T+S F +++DEYTTL + +RI S+
Sbjct: 122 YQDGSVKRQIRVDVSKASGINITSAIFGLSVLKSTRSEFWGYIKDEYTTLPETWDRILSS 181
Query: 220 IVEAEWIYDNM--------RTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAE 271
V+ +W + + + F A+ + ++A FA D S S Q TLY+
Sbjct: 182 DVDIKWRWKHFGDVSDVEANVSHFIEAFASARNASFKAFA--EDN---SMSAQATLYKMA 236
Query: 272 KTVLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRR 331
+ L+ V ++ + PNKHY+ ID+S + + D +Y P P GLI L R
Sbjct: 237 EKFLDCVPLADAVEYSWPNKHYVEIDLS-WHKGIRNTDKDAEVYLPQSAPNGLIKGTLTR 295
>UniRef50_O74409 Cluster: Probable uricase; n=1; Schizosaccharomyces
pombe|Rep: Probable uricase - Schizosaccharomyces pombe
(Fission yeast)
Length = 296
Score = 153 bits (370), Expect = 8e-36
Identities = 95/292 (32%), Positives = 149/292 (51%), Gaps = 16/292 (5%)
Query: 50 YGKSSVKLLH--VHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLL 107
YGK+ V+ + + H + E +V + L E +Y DN VV TD+QKNT+Y+
Sbjct: 12 YGKTLVRFMKKDICPKTKTHTVYEMDVQSLLTGELEESYTKADNSIVVPTDTQKNTIYVF 71
Query: 108 AKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQA-GTPHSHAFVFSPIAT 166
AK V PE F A + HF+ YK + A + PW R++ G PHSH+F+ +P T
Sbjct: 72 AKNNDVSVPEVFAAKLAKHFVDKYKHIHGAALDITITPWTRMEVQGKPHSHSFIRNPGET 131
Query: 167 RWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVEAEWI 226
R + V + + V S L + VLK+T S F +F + E+TTL + +RIFST ++ +
Sbjct: 132 RKTHVVFSEGKGFDVVSSLKDVLVLKSTGSGFTNFHKCEFTTLPEVTDRIFSTSIDCNYT 191
Query: 227 YDNMRT------ADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSE 280
+ + T DF++ + VK+ L+ FA S SVQ T+Y+ T++
Sbjct: 192 FKHFDTFEELAGFDFNSIYEKVKEITLETFALDD-----SESVQATMYKMADTIINTYPA 246
Query: 281 ITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRRR 332
I + +PNKHY I+++ P N+ +Y P P+G I + R+
Sbjct: 247 INEVYYALPNKHYFEINLA--PFNIDNLGSNCSLYQPQAYPSGYITCTVARK 296
>UniRef50_A6REK6 Cluster: Uricase; n=9; Ascomycota|Rep: Uricase -
Ajellomyces capsulatus NAm1
Length = 318
Score = 152 bits (369), Expect = 1e-35
Identities = 98/304 (32%), Positives = 153/304 (50%), Gaps = 28/304 (9%)
Query: 50 YGKSSVKLLHVHRDE--GHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLL 107
YGK +V++ VHR+E G H + E V L+ ET+Y DN VVATDS KNT+Y++
Sbjct: 10 YGKDNVRVYKVHRNEETGFHTVVEMTVCVLLEGDIETSYTKADNSVVVATDSMKNTIYIM 69
Query: 108 AKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQ-AGTPHSHAFVFSPIAT 166
AK + V PE F +++ +HF Y + A ++ W R+ G PH H+F+ T
Sbjct: 70 AKLHPVTPPELFASILGSHFTTTYPHIHTAHVDIVILRWTRMTFDGKPHPHSFLRDGTET 129
Query: 167 R-----------WSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVER 215
R S+ + + + S +SGL VLK+T S F +F++DEYTTL + +R
Sbjct: 130 RNVSAIVSEGNSGSKDITSLTSTISLTSSISGLSVLKSTNSQFHNFIRDEYTTLPETWDR 189
Query: 216 IFSTIVEAEWIYDNMRTAD--------FDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTL 267
+ ST V+A W + + D FD W +D L FA S SVQ+++
Sbjct: 190 VLSTNVDANWTWQPFTSVDAVKRAVPQFDETWRAARDITLRIFAHD-----NSASVQNSM 244
Query: 268 YQAEKTVLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYA 327
Y+ + +L + ++ ++PN HY +D+S + + +Y P P GLI
Sbjct: 245 YKMAEQILAVQPLLETVEYSLPNNHYFELDLS-WHKGLKNTGKNAEVYVPQSGPNGLIKC 303
Query: 328 QLRR 331
++ R
Sbjct: 304 KVGR 307
>UniRef50_Q9RV70 Cluster: Uricase; n=2; Deinococcus|Rep: Uricase -
Deinococcus radiodurans
Length = 298
Score = 149 bits (362), Expect = 8e-35
Identities = 100/294 (34%), Positives = 154/294 (52%), Gaps = 16/294 (5%)
Query: 42 RFELCDHGYGKSSVKLLHVHRDEGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQK 101
+ L ++ YGK+ V+L+ + R H +RE +V + A+ GDN ++VATD+ +
Sbjct: 15 KVRLGENNYGKAEVQLMKIKRGTPRHELREAKVRVAMYGDFGAAHSEGDNTDLVATDTVR 74
Query: 102 NTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQAGTP---HSHA 158
NTVY LAK+ + EEFG ++ HF+ + +V E+ WER+Q H HA
Sbjct: 75 NTVYGLAKEGFESSIEEFGKELLTHFVKVGPRVTGGFAEFTEHLWERVQTPAQPQGHDHA 134
Query: 159 FVFSPIATRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDE-YTTLTDAVERIF 217
FV + R + V V SG+ L VLKTT+S + +++ DE +TTL + +R+
Sbjct: 135 FV-RQMPKRTARVETQDGRRFTVTSGIEELYVLKTTESGWENYLLDERFTTLPETHDRVM 193
Query: 218 STIVEAEWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEK 277
+T V A+W Y + + D+D W V I F T YSPS+Q TLY + VL
Sbjct: 194 ATFVTAKWEY-AVESCDYDAVWERVYRQIQHTF-----TDHYSPSLQRTLYLMGEAVLSV 247
Query: 278 VSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAGLIYAQLRR 331
EI+ I MPNKH+L ++ +F + + + I H +P GL+ A + R
Sbjct: 248 CPEISRIWFQMPNKHHLVYNLGRFGL-----ENNNEILHVDPEPYGLMEAWVER 296
>UniRef50_P78609 Cluster: Uricase; n=25; Ascomycota|Rep: Uricase -
Pichia jadinii (Yeast) (Candida utilis)
Length = 303
Score = 137 bits (331), Expect = 4e-31
Identities = 94/305 (30%), Positives = 148/305 (48%), Gaps = 28/305 (9%)
Query: 50 YGKSSVKLLHVHRDEGH---HVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYL 106
YGK +VK L V +D + + E V L+ +T+Y DN +V TD+ KNT+ +
Sbjct: 10 YGKDNVKFLKVKKDPQNPKKQEVMEATVTCLLEGGFDTSYTEADNSSIVPTDTVKNTILV 69
Query: 107 LAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQA-GTPHSHAFVFSPIA 165
LAK + E F A + HF+ Y V ++++ W + G PH H+F+
Sbjct: 70 LAKTTEIWPIERFAAKLATHFVEKYSHVSGVSVKIVQDRWVKYAVDGKPHDHSFIHEGGE 129
Query: 166 TRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTIVEAEW 225
R +++ R + S + L VLK+T S F + + ++TTL +RI ST V+A W
Sbjct: 130 KRITDLYYKRSGDYKLSSAIKDLTVLKSTGSMFYGYNKCDFTTLQPTTDRILSTDVDATW 189
Query: 226 IYDN---------MRTAD---FDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKT 273
++DN + AD FDN + ++ L FA SPSVQ T++
Sbjct: 190 VWDNKKIGSVYDIAKAADKGIFDNVYNQAREITLTTFALE-----NSPSVQATMFNMATQ 244
Query: 274 VLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKG-DPRHFIYHPIDQPAGLIYAQLRRR 332
+LEK + + +PNKHY ID+ KG + + +++P P GLI + R+
Sbjct: 245 ILEKACSVYSVSYALPNKHYFLIDLK------WKGLENDNELFYPSPHPNGLIKCTVVRK 298
Query: 333 PKSKL 337
K+KL
Sbjct: 299 EKTKL 303
>UniRef50_Q75QK6 Cluster: Uricase; n=1; Aspergillus oryzae|Rep:
Uricase - Aspergillus oryzae
Length = 300
Score = 132 bits (319), Expect = 1e-29
Identities = 92/286 (32%), Positives = 140/286 (48%), Gaps = 38/286 (13%)
Query: 50 YGKSSVKLLHVHRDE--GHHVIREFEVFTELKLASETAYIL-GDNKEVVATDSQK----- 101
YGK +V++ VH+DE G + E V L ET+Y+ G N+ + + + +
Sbjct: 9 YGKDNVRVYKVHKDEKTGIQTVYEMTVCVLLGGEIETSYVTSGLNRSLESLANNRGLQLH 68
Query: 102 ---------------NTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPW 146
NT+Y+ AK+ V PE FG+++ HF+ Y + A +I + W
Sbjct: 69 QGRQQRHCRNRLHYQNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIICHRW 128
Query: 147 ERLQA-GTPHSHAFVFSPIATRWSEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDE 205
R+ G PH H+F+ R +V + + +KS LSGL VLK+T S F F++DE
Sbjct: 129 TRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDE 188
Query: 206 YTTLTDAVERIFSTIVEAEWIYDNM--------RTADFDNAWLTVKDAILDKFAGPPDTG 257
YTTL + +RI ST V+A W + N FD W T ++ L FA D
Sbjct: 189 YTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFA--EDN- 245
Query: 258 VYSPSVQHTLYQAEKTVLEKVSEITWIKMTMPNKHYLNID-MSKFP 302
S SVQ T+Y+ + +L + + ++ ++PNKHY I S FP
Sbjct: 246 --SASVQATMYKMAEQILARQQLVETVEYSLPNKHYFEIGRFSAFP 289
>UniRef50_Q4PGU1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 327
Score = 117 bits (281), Expect = 5e-25
Identities = 102/329 (31%), Positives = 153/329 (46%), Gaps = 37/329 (11%)
Query: 39 SGGRFELCDHGYGKSSVKLLHVHRDE---GHHVIREFEVFTELKLASET-AYILGDNKEV 94
S L YGK V++ + RD H + E+ V L S T +Y DN V
Sbjct: 6 SSSNVRLASASYGKDLVRIFRIVRDSKDPSSHRVAEYTVRCLLHGESLTPSYTEADNSPV 65
Query: 95 VATDSQKNTVYLLAKKY---GVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERL-- 149
VATD+ KNT+ LAK V PE + VVNHFL Y + + + +I++ W R+
Sbjct: 66 VATDTVKNTLNYLAKVLPAEDVLCPERYALNVVNHFLTTYSHIEKTEVDLIQHKWTRIVL 125
Query: 150 --QAGTPHSHAFVFSPIATRW----SEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQ 203
+ G H H+FV R E S + ++ G+ GL VLK++ SAF F +
Sbjct: 126 DQKDGGAHKHSFVRDGEEKRTVRALGERSGSEINVTTLEGGIKGLLVLKSSGSAFYGFHR 185
Query: 204 DEYTTLTDAVERIFSTIVEAEW------------IYDNMRTADFDNAWLTVKDAILDKFA 251
D +TTL + +RIFST VE + + + F + +VK +L FA
Sbjct: 186 DSFTTLKEVHDRIFSTEVECSYSIGLPSGGLTAVLKNPSSLPQFCDIHSSVKSHVLRVFA 245
Query: 252 GPPDTGVYSPSVQHTLYQAEKTVLEKVSEITW--IKMTMPNKHYLNIDMS-KFPVNVTKG 308
S SVQ T+Y+ + +L + T + +PNKHY+ ID+ K N+ +
Sbjct: 246 LDD-----SASVQATMYRMGEAILGDATNKTVKDVSFALPNKHYIPIDLGFKGLSNLDEK 300
Query: 309 DPRHFIYHPIDQPAGLIYAQLRRRPKSKL 337
+ F+ P P+G I A++ R +KL
Sbjct: 301 NAEVFL--PTAHPSGYIKAKIARLSAAKL 327
>UniRef50_Q5KBI4 Cluster: Uricase (Urate oxidase), putative; n=1;
Filobasidiella neoformans|Rep: Uricase (Urate oxidase),
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 311
Score = 116 bits (278), Expect = 1e-24
Identities = 100/307 (32%), Positives = 145/307 (47%), Gaps = 31/307 (10%)
Query: 50 YGKSSVKLLHVHRD-EGHHVIREFEVFTELKLASETAYILGDNKEVVATDSQKNTVYLLA 108
YGK VK+ V RD E HH++ E+ + L+ ET+Y DN VVATD+ KNT + A
Sbjct: 12 YGKDLVKVARVVRDGEQHHIV-EYTLRVLLEGEIETSYTEADNSCVVATDTVKNTCNIFA 70
Query: 109 K--KYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWERLQA-GTPHSHAFVFSPIA 165
K Y + P F + HF+ YK + + +I W R+ G PH +F+
Sbjct: 71 KTSPYVLDAP-VFALHLGLHFVTKYKHIHKCFVDIIGLKWSRISVDGKPHKWSFIRDGDE 129
Query: 166 TRWSE--VSQTRHEAVV---VKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVERIFSTI 220
E V T VK G+ L VLKT+ SAF +F +DE TTL D +RIFST
Sbjct: 130 KAIVECVVDGTAGPDAATANVKIGIKDLLVLKTSGSAFENFHRDENTTLADVADRIFSTS 189
Query: 221 VEAE----------WIYDNM----RTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHT 266
V + DN+ + DF + +LD FA S SVQ T
Sbjct: 190 VSLQCSISLPPNTPLTIDNLGSIAKELDFPKMKELILKDVLDTFATDE-----SASVQAT 244
Query: 267 LYQAEKTVLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKG-DPRHFIYHPIDQPAGLI 325
LY + +L + M +PNKHY+ +++S F ++ G + +++P P+G I
Sbjct: 245 LYLTLQKILASCPAVKDASMQLPNKHYIPVNLSAFGLDNKLGYEGGAEVFYPAADPSGYI 304
Query: 326 YAQLRRR 332
A + R+
Sbjct: 305 TATVTRK 311
>UniRef50_A5YRZ8 Cluster: Uricase; n=1; uncultured haloarchaeon|Rep:
Uricase - uncultured haloarchaeon
Length = 322
Score = 75.8 bits (178), Expect = 2e-12
Identities = 53/217 (24%), Positives = 98/217 (45%), Gaps = 9/217 (4%)
Query: 89 GDNKEVVATDSQKNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWER 148
GDN VVATDS KN +Y +Y T E + + L Y Q+ + P+++
Sbjct: 70 GDNSMVVATDSMKNFIYHHMGEYDGATLEGLLEYIGSEILDTYSQMEAVTMSADQLPFDK 129
Query: 149 LQAG-----TPHSHAFVFSPIATRWSEV--SQTRHEAVVVK--SGLSGLRVLKTTQSAFV 199
+ TP F S + ++E+ +T + + SG++G+ ++K ++F
Sbjct: 130 TEVPDDGEFTPSELVFGVSDSPSGYAEIRIDETNAGITITEHTSGVTGIELVKVKDNSFT 189
Query: 200 DFVQDEYTTLTDAVERIFSTIVEAEWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVY 259
+VQDEYTTL + R ++ W YDN TA + V + +
Sbjct: 190 GYVQDEYTTLPERENRTLYVGLDIFWTYDNAETALGSDPEAYVPAEQVSDIVQVVFDDMD 249
Query: 260 SPSVQHTLYQAEKTVLEKVSEITWIKMTMPNKHYLNI 296
S+Q +YQ + +L++ S++ ++ N+ ++ +
Sbjct: 250 VNSIQELIYQIGQRILKRFSQLNSVRFEANNRTWIGV 286
>UniRef50_Q9KEU0 Cluster: Uricase; n=1; Bacillus halodurans|Rep:
Uricase - Bacillus halodurans
Length = 329
Score = 69.3 bits (162), Expect = 1e-10
Identities = 55/214 (25%), Positives = 90/214 (42%), Gaps = 13/214 (6%)
Query: 89 GDNKEVVATDSQKNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWER 148
GDN V+ATDS KN + A + T E+F + FL Y + + +
Sbjct: 73 GDNSLVIATDSMKNFILRKAAFFNGSTMEDFLQFISKEFLNTYSHISSVSLSGDQLLFHE 132
Query: 149 LQAGTPHSHAFVFSPIATRWSEVSQ-----------TRHEAVVVKSGLSGLRVLKTTQSA 197
+ P + F S + + E + T ++ + SG+ GLR++K +S+
Sbjct: 133 VPI--PSTSGFQTSDLLFQQEESVKPFAKVEVRRMDTEYKVMEQLSGIQGLRLIKVKESS 190
Query: 198 FVDFVQDEYTTLTDAVERIFSTIVEAEWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTG 257
F ++QDEYTTL +A +R + W Y+N A V + A
Sbjct: 191 FYGYIQDEYTTLPEAYDRPLFLYLNMFWAYENPEDATGIKPDRYVSAEQVAAIAYTVFHE 250
Query: 258 VYSPSVQHTLYQAEKTVLEKVSEITWIKMTMPNK 291
+ PS+Q+ LYQ VL + ++ I N+
Sbjct: 251 MNCPSIQNLLYQIGLRVLMRFPQLVEISFESNNR 284
>UniRef50_Q02C45 Cluster: Urate oxidase; n=1; Solibacter usitatus
Ellin6076|Rep: Urate oxidase - Solibacter usitatus
(strain Ellin6076)
Length = 287
Score = 60.5 bits (140), Expect = 6e-08
Identities = 63/248 (25%), Positives = 102/248 (41%), Gaps = 16/248 (6%)
Query: 86 YILGDNKEVVATDSQKNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYP 145
Y GDN +VATDS KN + + E + + F+ Y + + P
Sbjct: 54 YTTGDNTNLVATDSMKNFIQRETCNFTGYDLESYCDFLARKFMATYPHTAGIQLSARQAP 113
Query: 146 WERLQAGTPHSHAFVFSPIATRWSEVSQTRH--EAVVVKSGLSGLRVLKTTQSAFVDFVQ 203
+ + G + A +AT E+ + E+V SG+ G R+L+ SAF F++
Sbjct: 114 YSGVAEGKV-AFAPSGPDVATACVELRRNGEALESVEASSGIHGFRLLRLGGSAFQGFLR 172
Query: 204 DEYTTLTDAVERIFSTIVEAEWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSV 263
D+YTTL D R ++ EW Y A +T A + + S S+
Sbjct: 173 DQYTTLPDIHNRPLHMWLDLEWHYIAPEAA-LTGGEVT---AQVRRLVHEGFHSFESGSI 228
Query: 264 QHTLYQAEKTVLEKVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFIYHPIDQPAG 323
Q +YQ +L + I+ +++ N+ + I V +GD R +Y P G
Sbjct: 229 QQVIYQLGTKMLADIPTISEVRLEANNRTWDTI--------VEQGD-RLGVYTDARPPYG 279
Query: 324 LIYAQLRR 331
+ LRR
Sbjct: 280 CLGLTLRR 287
>UniRef50_O32141 Cluster: Uricase; n=3; Bacillus|Rep: Uricase -
Bacillus subtilis
Length = 494
Score = 58.4 bits (135), Expect = 2e-07
Identities = 54/214 (25%), Positives = 89/214 (41%), Gaps = 15/214 (7%)
Query: 89 GDNKEVVATDSQKNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWER 148
GDN VVATDS KN + Y T E F V + FL Y + + P+E
Sbjct: 231 GDNTLVVATDSMKNFIQRHLASYEGTTTEGFLHYVAHRFLDTYSHMDTITLTGEDIPFEA 290
Query: 149 LQAGTPHSHAFVFSPIATRWSEVSQTRHEAVVVKSG-----------LSGLRVLKTTQSA 197
+ A S + R S ++R +SG + L+++K + ++
Sbjct: 291 MPA--YEEKELSTSRLVFRRSRNERSRSVLKAERSGNTITITEQYSEIMDLQLVKVSGNS 348
Query: 198 FVDFVQDEYTTLTDAVERIFSTIVEAEWIYDNMRTA-DFDNAWLTVKDAILDKFAGPPDT 256
FV F++DEYTTL + R + W Y+N + D A + + D A
Sbjct: 349 FVGFIRDEYTTLPEDGNRPLFVYLNISWQYENTNDSYASDPARYVAAEQVRD-LASTVFH 407
Query: 257 GVYSPSVQHTLYQAEKTVLEKVSEITWIKMTMPN 290
+ +PS+Q+ +Y +L + ++T + N
Sbjct: 408 ELETPSIQNLIYHIGCRILARFPQLTDVSFQSQN 441
>UniRef50_Q2SK85 Cluster: Predicted signal transduction protein
containing a membrane domain, an EAL and a GGDEF domain;
n=1; Hahella chejuensis KCTC 2396|Rep: Predicted signal
transduction protein containing a membrane domain, an
EAL and a GGDEF domain - Hahella chejuensis (strain KCTC
2396)
Length = 824
Score = 43.2 bits (97), Expect = 0.010
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 12/154 (7%)
Query: 20 ETPSPSLASPRVALTAAEDSGGR-FELCDHGYGKSSVKLLHVHRD-EGHHVIREFEVFTE 77
+TP L S +A+ A+ +GG F H S+ K L + RD + +++EF V+ +
Sbjct: 519 QTPELLLKSADLAMYEAKQAGGACFRFFTHALNTSAEKRLQLERDIQDGLIVKEFTVYLQ 578
Query: 78 LKLASETAYILGDNKEVVATDSQKNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEA 137
++ T + E VA + LL +++ + EE G H + + KQ+LEA
Sbjct: 579 PRVNLRTG--IATEFEAVARWNHPRLGVLLPEQF-ISVAEESG-----HLIELGKQLLEA 630
Query: 138 KCRVIEYPWERLQAGTPHSHAFVFSPIATRWSEV 171
C I+ + + G +F +P R +EV
Sbjct: 631 VCNAIKTLQQNV--GNDVKVSFNLAPHHLRMNEV 662
>UniRef50_Q8EH11 Cluster: Outer membrane porin, putative; n=5;
Shewanella|Rep: Outer membrane porin, putative -
Shewanella oneidensis
Length = 345
Score = 35.5 bits (78), Expect = 2.0
Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
Query: 79 KLASETAYILGDNKEVVATDSQKNTVYLLAKKYG---VKTPEEFGAVVVNHFLYMYKQVL 135
KL +Y+L DN + + N Y LA YG KT + + AV + + + +
Sbjct: 159 KLQLGVSYLLEDNHYSNNDNRRDNGNYQLAVTYGDKFFKTSDVYAAVAYSDGV----EDI 214
Query: 136 EAKCRVIEYPWERLQAGTPHSHAFVFSPIATRWSE 170
EA VI+Y W++ Q T H+ + + T W +
Sbjct: 215 EAYRGVIQYKWDKWQFATMLQHSQLVNTDKTDWQQ 249
>UniRef50_A4IQ09 Cluster: Lantibiotic mersacidin transporter system;
n=1; Geobacillus thermodenitrificans NG80-2|Rep:
Lantibiotic mersacidin transporter system - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 721
Score = 35.1 bits (77), Expect = 2.6
Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 14/98 (14%)
Query: 224 EWIYDNMRTADFDNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKT-----VLE-- 276
E YDN+ D D WL K ++ PPD +++ S+ H + E+ V+E
Sbjct: 530 EIFYDNVNLKDIDKQWLRRKIGVV-----PPDATLFNKSILHNISVYEENPSMDDVIEAA 584
Query: 277 KVSEITWIKMTMPNKHYLNIDMSKFPVNVTKGDPRHFI 314
K+++I M MP +Y + S+ +N++ G + +
Sbjct: 585 KIAQIHDEIMAMPMGYYTPV--SEMSMNISGGQKQRIM 620
>UniRef50_Q12W58 Cluster: Putative uncharacterized protein; n=1;
Methanococcoides burtonii DSM 6242|Rep: Putative
uncharacterized protein - Methanococcoides burtonii
(strain DSM 6242)
Length = 104
Score = 35.1 bits (77), Expect = 2.6
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 236 DNAWLTVKDAILDKFAGPPDTGVYSPSVQHTLYQAEKTVLEKVSEITWIKMTMPNKHYLN 295
+N W+ +KDA++ K + D G Y H +Y +K K + I MT NK +
Sbjct: 9 ENTWINIKDALI-KLSNYLDFG-YKSVYGHIIYDTKKVRAWKDRDKNLIPMTRHNKAIIR 66
Query: 296 IDMSKF 301
+D ++
Sbjct: 67 VDTQQY 72
>UniRef50_A6PT50 Cluster: Regulatory protein GntR, HTH; n=1;
Victivallis vadensis ATCC BAA-548|Rep: Regulatory
protein GntR, HTH - Victivallis vadensis ATCC BAA-548
Length = 392
Score = 34.7 bits (76), Expect = 3.5
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 89 GDNKEVVATDSQKNTVYLLAKKYGVKTPEEFGAVVVNHFLYMYKQVLEAKCRVIEYPWER 148
GD + D + + + A+K G K PEE + VN+F + Q ++ + +P+ R
Sbjct: 271 GDLAVICYDDIEAMRLVIAARKSGWKLPEEMAVMGVNNF--AFSQYVDPPLSTVLFPY-R 327
Query: 149 LQAGTPHSHAFVFSPIATRWSEVSQTRHEAVVVKSGLSGLR 189
AG A F ++SE + + E ++ S LR
Sbjct: 328 YMAGRMLKRALDFLEEREKFSEAALPQLEVLIRDSCCGRLR 368
>UniRef50_UPI0000E49053 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 303
Score = 33.9 bits (74), Expect = 6.0
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 23 SPSLASPRVALTAAED--SGGRFELCDHGYGKSSVKLLHVHRDEGHHVIREFEVFTELKL 80
+P A PR+ALT ED R L HG G+S +L H + H + + TE +L
Sbjct: 92 NPYAALPRLALTKGEDVREEARMSLI-HGLGRSHSELSHFRTRDSHRALLQDRPHTESRL 150
>UniRef50_UPI0000499B79 Cluster: lipase; n=1; Entamoeba histolytica
HM-1:IMSS|Rep: lipase - Entamoeba histolytica HM-1:IMSS
Length = 442
Score = 33.5 bits (73), Expect = 8.0
Identities = 17/37 (45%), Positives = 22/37 (59%)
Query: 265 HTLYQAEKTVLEKVSEITWIKMTMPNKHYLNIDMSKF 301
H+ Y+ EK+VL+K EIT IK+ K I SKF
Sbjct: 404 HSSYKYEKSVLQKYEEITGIKLVPNRKEEYKILSSKF 440
>UniRef50_Q3DY25 Cluster: Putative uncharacterized protein; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: Putative
uncharacterized protein - Chloroflexus aurantiacus
J-10-fl
Length = 355
Score = 33.5 bits (73), Expect = 8.0
Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 9/107 (8%)
Query: 171 VSQTRHEAVVVKSGLSGLRVLKT----TQSAFVDFVQDEYTTLTDAVERIF----STIVE 222
+S RH + GL + +L + QS ++ T+T +E F STI +
Sbjct: 3 LSNHRHSLWITCWGLVWILLLLSQPTAAQSTQPQMQVGDHITITGRIEVTFTGLPSTIDK 62
Query: 223 AEWIYDNMRTADFDNAWLTVKDAILDKFAG-PPDTGVYSPSVQHTLY 268
W ++ T + W+ V+D K+ PPD Y P LY
Sbjct: 63 IRWSWNQEPTDEVSWRWIEVEDGNATKWVNPPPDYNNYDPEAPPILY 109
>UniRef50_A7TI97 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 396
Score = 33.5 bits (73), Expect = 8.0
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 7/89 (7%)
Query: 169 SEVSQTRHEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTLTDAVER-------IFSTIV 221
S+V RH + + +SGL G+ +L TT V T++ ++ IF ++
Sbjct: 131 SDVKNNRHLSSINESGLEGITILSTTAGTSHSVVAATEATMSTVIDEEPYLHLTIFPKVI 190
Query: 222 EAEWIYDNMRTADFDNAWLTVKDAILDKF 250
++ T NA L +LDKF
Sbjct: 191 LFNKTTQSLHTYKLINAHLKCFTTVLDKF 219
>UniRef50_Q8TJL7 Cluster: Predicted protein; n=1; Methanosarcina
acetivorans|Rep: Predicted protein - Methanosarcina
acetivorans
Length = 674
Score = 33.5 bits (73), Expect = 8.0
Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
Query: 75 FTELKLASETAYILGDNKEVVATDSQKNTVYLLAKKY-GVKTPEEFGAVVVNHFLYMYKQ 133
FT+LK+AS Y L +N ++V +K T+ LL + Y +K + +N+FLY+ +
Sbjct: 248 FTKLKIASRCMYSL-NNSKLVPLFGKKITLALLREPYQSLKQAKSITIKKINYFLYVKNE 306
Query: 134 V 134
+
Sbjct: 307 M 307
>UniRef50_O13682 Cluster: Helicase swr1; n=1; Schizosaccharomyces
pombe|Rep: Helicase swr1 - Schizosaccharomyces pombe
(Fission yeast)
Length = 1288
Score = 33.5 bits (73), Expect = 8.0
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 176 HEAVVVKSGLSGLRVLKTTQSAFVDFVQDEYTTL--TDAVERI 216
HE + K LS LR+++T AF FV DE +L T+A RI
Sbjct: 778 HEEPMTKLDLSTLRLIRTDSEAFDTFVSDELNSLCATNAYNRI 820
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.317 0.132 0.393
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 385,729,102
Number of Sequences: 1657284
Number of extensions: 15759380
Number of successful extensions: 41834
Number of sequences better than 10.0: 39
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 41735
Number of HSP's gapped (non-prelim): 45
length of query: 337
length of database: 575,637,011
effective HSP length: 101
effective length of query: 236
effective length of database: 408,251,327
effective search space: 96347313172
effective search space used: 96347313172
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 73 (33.5 bits)
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