Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001323-TA|BGIBMGA001323-PA|IPR002347|Glucose/ribitol
dehydrogenase, IPR002198|Short-chain dehydrogenase/reductase SDR
(254 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p... 323 2e-87
UniRef50_UPI0000E48B21 Cluster: PREDICTED: similar to MGC79752 p... 282 5e-75
UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p... 220 3e-56
UniRef50_Q15ER8 Cluster: U2 snRNP splicing factor small subunit-... 217 3e-55
UniRef50_UPI0000E47988 Cluster: PREDICTED: similar to short-chai... 199 6e-50
UniRef50_UPI0000E499EA Cluster: PREDICTED: similar to ENSANGP000... 196 6e-49
UniRef50_Q9NBB5 Cluster: 3-dehydroecdysone 3alpha-reductase; n=1... 182 6e-45
UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chai... 177 2e-43
UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR... 155 8e-37
UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;... 149 5e-35
UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1; ... 146 4e-34
UniRef50_Q67RW6 Cluster: Ketoreductase; n=5; Bacteria|Rep: Ketor... 143 4e-33
UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 140 2e-32
UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Re... 139 7e-32
UniRef50_A1C190 Cluster: Oxidoreductase; n=10; Streptomyces|Rep:... 137 2e-31
UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R... 137 3e-31
UniRef50_Q7CZN0 Cluster: AGR_C_2317p; n=3; Proteobacteria|Rep: A... 137 3e-31
UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR... 137 3e-31
UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 137 3e-31
UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1; ... 136 4e-31
UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 134 2e-30
UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR... 134 3e-30
UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r... 133 4e-30
UniRef50_Q89K11 Cluster: Oxidoreductase; n=6; Proteobacteria|Rep... 132 1e-29
UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici... 132 1e-29
UniRef50_Q1IK61 Cluster: Short-chain dehydrogenase/reductase SDR... 131 1e-29
UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;... 131 1e-29
UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 131 1e-29
UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1;... 131 2e-29
UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain dehydrogena... 130 3e-29
UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR... 130 3e-29
UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 129 6e-29
UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;... 129 6e-29
UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bactero... 128 1e-28
UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 128 1e-28
UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1; ... 128 2e-28
UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; ... 127 2e-28
UniRef50_A3H8L6 Cluster: Short-chain dehydrogenase/reductase SDR... 127 2e-28
UniRef50_Q28Q26 Cluster: Short-chain dehydrogenase/reductase SDR... 127 3e-28
UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 127 3e-28
UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR... 127 3e-28
UniRef50_Q3IVH5 Cluster: Short-chain dehydrogenase/reductase SDR... 126 4e-28
UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6; ... 126 4e-28
UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR... 126 5e-28
UniRef50_Q0RF25 Cluster: Putative oxidoreductase; short-chain de... 125 9e-28
UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcoh... 125 9e-28
UniRef50_A1UII7 Cluster: Short-chain dehydrogenase/reductase SDR... 125 9e-28
UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 124 2e-27
UniRef50_A1DKR3 Cluster: Short chain dehydrogenase/reductase fam... 124 2e-27
UniRef50_Q01TL3 Cluster: Short-chain dehydrogenase/reductase SDR... 124 2e-27
UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR... 124 3e-27
UniRef50_Q23618 Cluster: Putative uncharacterized protein; n=2; ... 124 3e-27
UniRef50_Q930L7 Cluster: Putative; n=1; Sinorhizobium meliloti|R... 123 5e-27
UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 123 5e-27
UniRef50_Q126U8 Cluster: Short-chain dehydrogenase/reductase SDR... 123 5e-27
UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 123 5e-27
UniRef50_A0FWP6 Cluster: Short-chain dehydrogenase/reductase SDR... 122 7e-27
UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR... 122 9e-27
UniRef50_A1ZKI7 Cluster: 3-oxoacyl-acyl-carrier-protein reductas... 122 9e-27
UniRef50_Q5NZC3 Cluster: Predicted short chain dehydrogenase; n=... 122 1e-26
UniRef50_A3IE79 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 122 1e-26
UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR... 122 1e-26
UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 121 2e-26
UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 120 3e-26
UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 120 3e-26
UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 120 3e-26
UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 120 3e-26
UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc... 120 4e-26
UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 120 4e-26
UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 120 5e-26
UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR... 120 5e-26
UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR... 119 6e-26
UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR... 119 6e-26
UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Str... 119 6e-26
UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma... 119 6e-26
UniRef50_Q6MLN8 Cluster: Oxidoreductase; n=1; Bdellovibrio bacte... 119 8e-26
UniRef50_Q333V8 Cluster: NAD or NADP oxidoreductase; n=1; Microm... 119 8e-26
UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR... 119 8e-26
UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena... 119 8e-26
UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 118 1e-25
UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=... 118 1e-25
UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOH... 118 1e-25
UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR... 118 1e-25
UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 118 1e-25
UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogena... 118 2e-25
UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein... 118 2e-25
UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 118 2e-25
UniRef50_Q1BBB6 Cluster: Short-chain dehydrogenase/reductase SDR... 118 2e-25
UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR... 118 2e-25
UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 118 2e-25
UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR... 118 2e-25
UniRef50_Q2G4A5 Cluster: Short-chain dehydrogenase/reductase SDR... 117 3e-25
UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3; ... 117 3e-25
UniRef50_Q982N5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 117 3e-25
UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 117 3e-25
UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR... 117 3e-25
UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 117 3e-25
UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2; ... 117 3e-25
UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 116 4e-25
UniRef50_P50162 Cluster: Tropinone reductase 1; n=77; Viridiplan... 116 4e-25
UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 116 6e-25
UniRef50_Q46UI8 Cluster: Short-chain dehydrogenase/reductase SDR... 116 6e-25
UniRef50_Q3W8G5 Cluster: Short-chain dehydrogenase/reductase SDR... 116 6e-25
UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob... 116 6e-25
UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|R... 116 6e-25
UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;... 116 6e-25
UniRef50_A0HJB5 Cluster: Short-chain dehydrogenase/reductase SDR... 116 8e-25
UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR... 116 8e-25
UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 115 1e-24
UniRef50_Q13GE7 Cluster: Putative short-chain dehydrogenase/redu... 115 1e-24
UniRef50_A3Q322 Cluster: Short-chain dehydrogenase/reductase SDR... 115 1e-24
UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR... 115 1e-24
UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR... 115 1e-24
UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13;... 115 1e-24
UniRef50_Q5FPE5 Cluster: NAD(P)-dependent glucose 1-dehydrogenas... 115 1e-24
UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase fam... 115 1e-24
UniRef50_P66781 Cluster: Uncharacterized oxidoreductase Rv1350/M... 115 1e-24
UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 114 2e-24
UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 114 2e-24
UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 114 2e-24
UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 114 2e-24
UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 114 2e-24
UniRef50_A0JC04 Cluster: (R)-2-octanol dehydrogenase; n=2; Pichi... 114 2e-24
UniRef50_Q3KDE6 Cluster: Short-chain dehydrogenase/reductase SDR... 113 3e-24
UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR... 113 3e-24
UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 113 3e-24
UniRef50_A0JTT9 Cluster: Short-chain dehydrogenase/reductase SDR... 113 3e-24
UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 113 3e-24
UniRef50_Q82KL5 Cluster: Putative dehydrogenase; n=1; Streptomyc... 113 4e-24
UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR... 113 4e-24
UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain dehydrogena... 113 4e-24
UniRef50_P95719 Cluster: Ata4 protein; n=2; Actinomycetales|Rep:... 113 4e-24
UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR... 113 4e-24
UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 113 4e-24
UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR... 113 4e-24
UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 113 5e-24
UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 113 5e-24
UniRef50_Q9JN17 Cluster: Yhg; n=6; Rhizobiaceae|Rep: Yhg - Agrob... 113 5e-24
UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1... 113 5e-24
UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR... 113 5e-24
UniRef50_A5UQR1 Cluster: Short-chain dehydrogenase/reductase SDR... 113 5e-24
UniRef50_A4XFC0 Cluster: Short-chain dehydrogenase/reductase SDR... 113 5e-24
UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR... 113 5e-24
UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reducta... 113 5e-24
UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 112 7e-24
UniRef50_Q89PN1 Cluster: Blr3449 protein; n=2; Bradyrhizobium|Re... 112 7e-24
UniRef50_Q7CHM2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 112 7e-24
UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 112 7e-24
UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR... 112 9e-24
UniRef50_Q6JHM5 Cluster: Putative oxidoreductase, short chain de... 112 9e-24
UniRef50_A7NL33 Cluster: Short-chain dehydrogenase/reductase SDR... 112 9e-24
UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR... 112 9e-24
UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR... 112 9e-24
UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR... 112 9e-24
UniRef50_A0J1E4 Cluster: Short-chain dehydrogenase/reductase SDR... 112 9e-24
UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot... 111 1e-23
UniRef50_A3ZX88 Cluster: Putative dehydrogenase; n=1; Blastopire... 111 1e-23
UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 111 1e-23
UniRef50_Q9A872 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 111 2e-23
UniRef50_Q89UV5 Cluster: Dehydrogenase; n=12; Alphaproteobacteri... 111 2e-23
UniRef50_Q47PV9 Cluster: Short chain dehydrogenase; n=1; Thermob... 111 2e-23
UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 111 2e-23
UniRef50_Q9REP0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 111 2e-23
UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23
UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23
UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23
UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23
UniRef50_A4FIJ5 Cluster: Oxidoreductase, short chain dehydrogena... 111 2e-23
UniRef50_A1SC75 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23
UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=... 111 2e-23
UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 111 2e-23
UniRef50_Q3WHY3 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23
UniRef50_Q3WEN2 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23
UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=... 110 3e-23
UniRef50_Q1QUQ5 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23
UniRef50_Q1JZ17 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23
UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23
UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 110 3e-23
UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase... 110 3e-23
UniRef50_A5FD58 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23
UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23
UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23
UniRef50_Q89W00 Cluster: Blr0893 protein; n=7; Bradyrhizobiaceae... 110 4e-23
UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 110 4e-23
UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 110 4e-23
UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR... 110 4e-23
UniRef50_A6UBN3 Cluster: Short-chain dehydrogenase/reductase SDR... 110 4e-23
UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR... 110 4e-23
UniRef50_A5NTZ6 Cluster: Short-chain dehydrogenase/reductase SDR... 110 4e-23
UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Re... 110 4e-23
UniRef50_Q0UWB9 Cluster: Putative uncharacterized protein; n=1; ... 110 4e-23
UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ... 110 4e-23
UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family memb... 110 4e-23
UniRef50_UPI0000DAE1BB Cluster: oxidoreductase, short chain dehy... 109 5e-23
UniRef50_Q987X7 Cluster: Probable short-chain dehydrogenase; n=1... 109 5e-23
UniRef50_Q67QU0 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 109 5e-23
UniRef50_Q5P686 Cluster: Subunit of 2-[hydroxy(Phenyl)methyl]-su... 109 5e-23
UniRef50_A0VT49 Cluster: Short-chain dehydrogenase/reductase SDR... 109 5e-23
UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb... 109 5e-23
UniRef50_Q5V8A5 Cluster: LtxD; n=2; Bacteria|Rep: LtxD - Lyngbya... 109 7e-23
UniRef50_Q0RL77 Cluster: Putative Short chain dehydrogenase; n=1... 109 7e-23
UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp. HTCC2601|... 109 7e-23
UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentispha... 109 7e-23
UniRef50_A0Z5T7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 109 7e-23
UniRef50_A0GDY0 Cluster: Short-chain dehydrogenase/reductase SDR... 109 7e-23
UniRef50_A0GDT9 Cluster: Short-chain dehydrogenase/reductase SDR... 109 7e-23
UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 109 7e-23
UniRef50_Q39MZ9 Cluster: Short-chain dehydrogenase/reductase SDR... 109 9e-23
UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR... 109 9e-23
UniRef50_A6T0X0 Cluster: Glucose-1-dehydrogenase, (3-oxoacyl-(Ac... 109 9e-23
UniRef50_A4XF86 Cluster: Short-chain dehydrogenase/reductase SDR... 109 9e-23
UniRef50_A3WFK2 Cluster: Glucose dehydrogenase; n=1; Erythrobact... 109 9e-23
UniRef50_A1WWM8 Cluster: Short-chain dehydrogenase/reductase SDR... 109 9e-23
UniRef50_A1W5S4 Cluster: Short-chain dehydrogenase/reductase SDR... 109 9e-23
UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 109 9e-23
UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 109 9e-23
UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6... 108 1e-22
UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 108 1e-22
UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR... 108 1e-22
UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR... 108 1e-22
UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like ... 108 1e-22
UniRef50_Q9EX74 Cluster: SDR-like enzyme; n=1; Rhodococcus eryth... 108 1e-22
UniRef50_Q2CH74 Cluster: Short-chain alcohol dehydrogenase; n=1;... 108 1e-22
UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 108 1e-22
UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholder... 108 1e-22
UniRef50_Q0FPS1 Cluster: Probable dehydrogenase; n=1; Roseovariu... 108 1e-22
UniRef50_Q04DL8 Cluster: Acetoin reductase; n=2; Oenococcus oeni... 108 1e-22
UniRef50_Q7UP98 Cluster: Oxidoreductase, short chain dehydrogena... 108 2e-22
UniRef50_Q4FPW9 Cluster: Possible Short-chain dehydrogenase/redu... 108 2e-22
UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogena... 108 2e-22
UniRef50_Q12JI9 Cluster: Short-chain dehydrogenase/reductase SDR... 108 2e-22
UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 108 2e-22
UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 108 2e-22
UniRef50_Q0I8V1 Cluster: Glucose 1-dehydrogenase; n=5; Bacteria|... 108 2e-22
UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR... 108 2e-22
UniRef50_A5VEH5 Cluster: Short-chain dehydrogenase/reductase SDR... 108 2e-22
UniRef50_A1ZIV8 Cluster: Short-chain dehydrogenase/reductase SDR... 108 2e-22
UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR... 108 2e-22
UniRef50_Q9BY49 Cluster: Peroxisomal trans-2-enoyl-CoA reductase... 108 2e-22
UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 107 2e-22
UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 107 2e-22
UniRef50_Q3M510 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22
UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22
UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22
UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22
UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=... 107 2e-22
UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 107 2e-22
UniRef50_Q2UFW9 Cluster: Dehydrogenases with different specifici... 107 2e-22
UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 107 3e-22
UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 107 3e-22
UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 107 3e-22
UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 107 3e-22
UniRef50_Q39NI4 Cluster: Short-chain dehydrogenase/reductase SDR... 107 3e-22
UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-22
UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 107 3e-22
UniRef50_A3KJN1 Cluster: Putative 3-oxoacyl-acyl-carrier protein... 107 3e-22
UniRef50_A1SCT9 Cluster: Short-chain dehydrogenase/reductase SDR... 107 3e-22
UniRef50_A0JX96 Cluster: Short-chain dehydrogenase/reductase SDR... 107 3e-22
UniRef50_Q8RDH9 Cluster: Dehydrogenases with different specifici... 107 4e-22
UniRef50_Q3KCL1 Cluster: Short-chain dehydrogenase/reductase SDR... 107 4e-22
UniRef50_Q39MU4 Cluster: Short-chain dehydrogenase/reductase SDR... 107 4e-22
UniRef50_Q18YK8 Cluster: Short-chain dehydrogenase/reductase SDR... 107 4e-22
UniRef50_Q0AVP7 Cluster: Short-chain dehydrogenase/reductase SDR... 107 4e-22
UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR... 107 4e-22
UniRef50_P12310 Cluster: Glucose 1-dehydrogenase; n=13; cellular... 107 4e-22
UniRef50_Q21929 Cluster: Probable L-xylulose reductase; n=3; Bil... 107 4e-22
UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 106 5e-22
UniRef50_Q2S4K7 Cluster: Oxidoreductase, short chain dehydrogena... 106 5e-22
UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter... 106 5e-22
UniRef50_Q1YP85 Cluster: Short chain dehydrogenase; n=1; gamma p... 106 5e-22
UniRef50_A0QXD6 Cluster: L-xylulose reductase; n=2; Actinomyceta... 106 5e-22
UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family memb... 106 5e-22
UniRef50_Q62E80 Cluster: Acetoacetyl-CoA reductase; n=60; Proteo... 106 6e-22
UniRef50_Q3W9G7 Cluster: Short-chain dehydrogenase/reductase SDR... 106 6e-22
UniRef50_Q2BK08 Cluster: Pteridine reductase; n=1; Neptuniibacte... 106 6e-22
UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR... 106 6e-22
UniRef50_A5EDQ3 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 106 6e-22
UniRef50_A4CNY9 Cluster: Oxidoreductase, short chain dehydrogena... 106 6e-22
UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR... 106 6e-22
UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 106 6e-22
UniRef50_Q9PDC2 Cluster: Pteridine reductase 1; n=11; Xanthomona... 105 8e-22
UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_Q6W1L9 Cluster: Short chain dehydrogenase; n=2; Rhizobi... 105 8e-22
UniRef50_Q1GNJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_Q03RV5 Cluster: 3-oxoacyl-acyl carrier protein reductas... 105 8e-22
UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_A4T6Z1 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_A1VQU4 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_A0XC03 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22
UniRef50_Q9YDK1 Cluster: Putative dehydrogenase; n=1; Aeropyrum ... 105 8e-22
UniRef50_Q4J9F2 Cluster: Short chain dehydrogenase; n=1; Sulfolo... 105 8e-22
UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 105 8e-22
UniRef50_Q9RWD9 Cluster: Oxidoreductase, short-chain dehydrogena... 105 1e-21
UniRef50_Q931B7 Cluster: Putative; n=2; Sinorhizobium|Rep: Putat... 105 1e-21
UniRef50_Q83BJ4 Cluster: Oxidoreductase, short chain dehydrogena... 105 1e-21
UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_Q676G3 Cluster: Probable short-chain dehydrogenase; n=1... 105 1e-21
UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 105 1e-21
UniRef50_A5V529 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo... 105 1e-21
UniRef50_A5CY54 Cluster: Dehydrogenases with different specifici... 105 1e-21
UniRef50_A4FJJ0 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_A0HIJ6 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_Q8ZYG0 Cluster: Short chain dehydrogenase; n=2; Pyrobac... 105 1e-21
UniRef50_Q92GE0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 105 1e-21
UniRef50_Q98H65 Cluster: Short chain dehydrogenase or 3-ketoacyl... 105 1e-21
UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 105 1e-21
UniRef50_Q3MGE9 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_Q3IVH6 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_Q398J5 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 105 1e-21
UniRef50_Q1PVP3 Cluster: Similar to 3-oxoacyl-[acyl carrier prot... 105 1e-21
UniRef50_Q1LDG6 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_Q1AYM3 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21
UniRef50_Q143V4 Cluster: Putative dehydrogenase; n=1; Burkholder... 105 1e-21
UniRef50_A6AFC6 Cluster: Oxidoreductase, short chain dehydrogena... 105 1e-21
UniRef50_A5D4R4 Cluster: Dehydrogenases with different specifici... 105 1e-21
UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola... 105 1e-21
UniRef50_Q47QE8 Cluster: Probable short-chain type dehydrogenase... 104 2e-21
UniRef50_Q5MPN9 Cluster: Hypothetical 3-oxoacyl-acyl carrier pro... 104 2e-21
UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 104 2e-21
UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 104 2e-21
UniRef50_A5VBH4 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_A5UT09 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine ... 104 2e-21
UniRef50_A0VRG5 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;... 104 2e-21
UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=... 104 2e-21
UniRef50_Q5BLE6 Cluster: Zgc:113054; n=8; Euteleostomi|Rep: Zgc:... 104 2e-21
UniRef50_Q983U4 Cluster: Putative dehydrogenase; n=1; Mesorhizob... 104 2e-21
UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 104 2e-21
UniRef50_Q62GI3 Cluster: Oxidoreductase, short-chain dehydrogena... 104 2e-21
UniRef50_Q2J935 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_Q2G822 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candida... 104 2e-21
UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_A5UX97 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_A3I4P3 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_A2W1T9 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21
UniRef50_Q8YJQ0 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 103 3e-21
UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 103 3e-21
UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o... 103 3e-21
UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 103 3e-21
UniRef50_Q391K0 Cluster: Short-chain dehydrogenase/reductase SDR... 103 3e-21
UniRef50_Q3WFB3 Cluster: Short-chain dehydrogenase/reductase SDR... 103 3e-21
UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 103 3e-21
UniRef50_Q08XI3 Cluster: 2-(S)-hydroxypropyl-CoM dehydrogenase; ... 103 3e-21
UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=... 103 3e-21
UniRef50_A6G1V5 Cluster: Short chain dehydrogenase; n=1; Plesioc... 103 3e-21
UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacter... 103 3e-21
UniRef50_A3K6R9 Cluster: Short-chain dehydrogenase/reductase SDR... 103 3e-21
UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 103 3e-21
UniRef50_Q9RT26 Cluster: 3-oxoacyl-acyl carrier protein reductas... 103 4e-21
UniRef50_Q8R6S8 Cluster: Dehydrogenases with different specifici... 103 4e-21
UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill... 103 4e-21
UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Sho... 103 4e-21
UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21
UniRef50_Q0FYP2 Cluster: Probable oxidoreductase protein, short-... 103 4e-21
UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21
UniRef50_A7HGC3 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21
UniRef50_A5V6V5 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21
UniRef50_A4M3J4 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21
UniRef50_A3Q7E9 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21
UniRef50_Q8LFZ4 Cluster: Short chain alcohol dehydrogenase-like;... 103 4e-21
UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR... 103 6e-21
UniRef50_Q395K9 Cluster: Short-chain dehydrogenase/reductase SDR... 103 6e-21
UniRef50_Q2S401 Cluster: Oxidoreductase, short chain dehydrogena... 103 6e-21
UniRef50_Q3WJ90 Cluster: Short-chain dehydrogenase/reductase SDR... 103 6e-21
UniRef50_Q3WCZ4 Cluster: Short-chain dehydrogenase/reductase SDR... 103 6e-21
UniRef50_Q1NA92 Cluster: Gluconate 5-dehydrogenase; n=1; Sphingo... 103 6e-21
UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 103 6e-21
UniRef50_A5VE69 Cluster: Short-chain dehydrogenase/reductase SDR... 103 6e-21
UniRef50_A5I7D8 Cluster: Sorbitol-6-phosphate 2-dehydrogenase; n... 103 6e-21
UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 103 6e-21
UniRef50_A7D7F1 Cluster: Short-chain dehydrogenase/reductase SDR... 103 6e-21
UniRef50_A2BN81 Cluster: Short chain dehydrogenase; n=1; Hyperth... 103 6e-21
UniRef50_Q9GKX2 Cluster: Dehydrogenase/reductase SDR family memb... 103 6e-21
UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 102 8e-21
UniRef50_Q883G7 Cluster: Oxidoreductase, short chain dehydrogena... 102 8e-21
UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21
UniRef50_Q3W2E5 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21
UniRef50_Q3F0M6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 102 8e-21
UniRef50_Q2C7C6 Cluster: Oxidoreductase, short-chain dehydrogena... 102 8e-21
UniRef50_Q1VSS0 Cluster: Gluconate 5-dehydrogenase, putative; n=... 102 8e-21
UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=... 102 8e-21
UniRef50_Q0K556 Cluster: Short chain dehydrogenase; n=1; Ralston... 102 8e-21
UniRef50_A7IEE4 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21
UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 102 8e-21
UniRef50_A3U1B5 Cluster: Putative short chain dehydrogenase; n=1... 102 8e-21
UniRef50_A0YDP4 Cluster: Short chain dehydrogenase; n=1; marine ... 102 8e-21
UniRef50_A0QH10 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21
UniRef50_Q9URX0 Cluster: Short chain dehydrogenase; n=1; Schizos... 102 8e-21
UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 102 8e-21
UniRef50_Q8YHX9 Cluster: SHORT-CHAIN DEHYDROGENASE; n=10; Bacter... 102 1e-20
UniRef50_Q7D6M3 Cluster: Oxidoreductase, short-chain dehydrogena... 102 1e-20
UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 102 1e-20
UniRef50_Q5LMF4 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 102 1e-20
UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 102 1e-20
UniRef50_Q2J6E1 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20
UniRef50_Q03ND1 Cluster: 3-oxoacyl-acyl carrier protein reductas... 102 1e-20
UniRef50_A4XEF9 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20
UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro... 102 1e-20
UniRef50_A1UD00 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20
UniRef50_A7D6X0 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20
UniRef50_O86034 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 102 1e-20
UniRef50_Q8U673 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 101 1e-20
UniRef50_Q89EA2 Cluster: Gdh protein; n=3; Bradyrhizobium|Rep: G... 101 1e-20
UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll... 101 1e-20
UniRef50_Q62GY7 Cluster: Oxidoreductase, short-chain dehydrogena... 101 1e-20
UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_Q39DX6 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_Q11C90 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 101 1e-20
UniRef50_A1SIL0 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_A0GHU7 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20
UniRef50_A1DIX9 Cluster: 1,3,6,8-tetrahydroxynaphthalene reducta... 101 1e-20
UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 101 1e-20
UniRef50_Q9HT49 Cluster: Probable short-chain dehydrogenase; n=5... 101 2e-20
UniRef50_Q89FM8 Cluster: Dehydrogenase; n=1; Bradyrhizobium japo... 101 2e-20
UniRef50_Q5YV43 Cluster: Putative short chain dehydrogenase; n=1... 101 2e-20
UniRef50_Q5KW73 Cluster: 3-ketoacyl-[acyl carrier protein] reduc... 101 2e-20
UniRef50_Q1NHB1 Cluster: Oxidoreductase; n=1; Sphingomonas sp. S... 101 2e-20
UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ... 101 2e-20
UniRef50_Q1GHX9 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_Q0I7J4 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 101 2e-20
UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 101 2e-20
UniRef50_P80869 Cluster: Glucose 1-dehydrogenase 2; n=39; Bacill... 101 2e-20
UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=... 101 2e-20
UniRef50_Q8YNV5 Cluster: Alr4456 protein; n=14; Bacteria|Rep: Al... 101 2e-20
UniRef50_Q602S5 Cluster: Oxidoreductase, short chain dehydrogena... 101 2e-20
UniRef50_Q39MZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_Q1RS55 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 101 2e-20
UniRef50_A5V448 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_A4W910 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_A1UGA4 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20
UniRef50_A1RDP9 Cluster: Oxidoreductase, short chain dehydrogena... 101 2e-20
UniRef50_UPI00015BAF2E Cluster: short-chain dehydrogenase/reduct... 100 3e-20
UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 100 3e-20
UniRef50_Q53W85 Cluster: Oxidoreductase, short-chain dehydrogena... 100 3e-20
UniRef50_Q2CHI2 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20
UniRef50_Q0SJP8 Cluster: Short chain dehydrogenase; n=1; Rhodoco... 100 3e-20
UniRef50_Q08Z99 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 100 3e-20
UniRef50_A1S186 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20
UniRef50_P52037 Cluster: Uncharacterized oxidoreductase ygfF; n=... 100 3e-20
UniRef50_Q9RJU5 Cluster: Probable oxidoreductase; n=1; Streptomy... 100 4e-20
UniRef50_Q5NW77 Cluster: Short-chain alcohol dehydrogenase; n=2;... 100 4e-20
UniRef50_Q2N2P3 Cluster: 3-oxoacyl-carrier-protein reductase; n=... 100 4e-20
UniRef50_Q1NAB3 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_Q13GR0 Cluster: Putative short-chain dehydrogenase/redu... 100 4e-20
UniRef50_Q01XW0 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_A6EBP7 Cluster: Short chain dehydrogenase; n=1; Pedobac... 100 4e-20
UniRef50_A4XEP3 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_A3VA26 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_A1R756 Cluster: Putative 3-oxoacyl-(Acyl carrier protei... 100 4e-20
UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20
UniRef50_Q8YDW1 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 99 5e-20
UniRef50_Q62BE5 Cluster: Oxidoreductase, short chain dehydrogena... 99 5e-20
UniRef50_Q3IVC8 Cluster: Short-chain alcohol dehydrogenases; n=2... 99 5e-20
UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 99 5e-20
UniRef50_Q1YS84 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_Q1M6N2 Cluster: Putative short-chain dehydrogenase/redu... 99 5e-20
UniRef50_Q0RTS7 Cluster: Putative ketoreductase, short chain deh... 99 5e-20
UniRef50_A7HFH2 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_A1SG64 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_A0R386 Cluster: Dehydrogenase/reductase SDR family prot... 99 5e-20
UniRef50_A0LVM3 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20
UniRef50_A2QKU0 Cluster: Contig An05c0050, complete genome; n=3;... 99 5e-20
UniRef50_Q89P11 Cluster: Oxidoreductase; n=8; Proteobacteria|Rep... 100 7e-20
UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-... 100 7e-20
UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 100 7e-20
UniRef50_Q0AT35 Cluster: Short-chain dehydrogenase/reductase SDR... 100 7e-20
UniRef50_A5UYE2 Cluster: Short-chain dehydrogenase/reductase SDR... 100 7e-20
UniRef50_A1BC68 Cluster: Short-chain dehydrogenase/reductase SDR... 100 7e-20
UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR... 100 7e-20
UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR... 100 7e-20
UniRef50_Q9ANA1 Cluster: ID403; n=2; Proteobacteria|Rep: ID403 -... 99 9e-20
UniRef50_Q930L3 Cluster: Putative; n=2; Sinorhizobium|Rep: Putat... 99 9e-20
UniRef50_Q8UJN8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 99 9e-20
UniRef50_Q8UAP0 Cluster: Dehydrogenase; n=7; Bacteria|Rep: Dehyd... 99 9e-20
UniRef50_Q7WPD3 Cluster: Probable short-chain dehydrogenase; n=1... 99 9e-20
UniRef50_Q6D4I9 Cluster: 2-keto-3-deoxygluconate oxidoreductase;... 99 9e-20
UniRef50_Q57A51 Cluster: Oxidoreductase, short-chain dehydrogena... 99 9e-20
UniRef50_Q3E250 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_Q1NH34 Cluster: Putative uncharacterized protein; n=1; ... 99 9e-20
UniRef50_A6W647 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_A6C1B7 Cluster: Putative uncharacterized protein; n=1; ... 99 9e-20
UniRef50_A5V4T0 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_A1SNX1 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_A1HSQ5 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20
UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 99 9e-20
UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 99 1e-19
UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri... 99 1e-19
>UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p -
Drosophila melanogaster (Fruit fly)
Length = 269
Score = 323 bits (794), Expect = 2e-87
Identities = 160/256 (62%), Positives = 185/256 (72%), Gaps = 2/256 (0%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS--I 58
MNFAGKVV +K GA L+L GRNVENL+KV+ +C K + + +
Sbjct: 14 MNFAGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALV 73
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 118
D+ KE+D ++I +T+ YGKLDVLVNNAGIIETGTIE TSL QYDR+MNTN+R+IY+
Sbjct: 74 VGDIAKEADTQRIWSETLQQYGKLDVLVNNAGIIETGTIETTSLEQYDRVMNTNLRAIYH 133
Query: 119 LTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
LTMLA P L+++KG GIRSFPGVLAYNISK VDQFTRCVALELA KGVRVN
Sbjct: 134 LTMLATPELVKTKGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVN 193
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
CVNPGV +T L RGG+ E Y FLE +K THALGRPG EVAA IAFLASD AS T
Sbjct: 194 CVNPGVTVTNLHARGGMDAETYKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFST 253
Query: 239 GASVPVDGGRHAMCPR 254
G S+PVDGGRHAMCPR
Sbjct: 254 GVSLPVDGGRHAMCPR 269
>UniRef50_UPI0000E48B21 Cluster: PREDICTED: similar to MGC79752
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to MGC79752 protein -
Strongylocentrotus purpuratus
Length = 303
Score = 282 bits (692), Expect = 5e-75
Identities = 134/231 (58%), Positives = 175/231 (75%), Gaps = 2/231 (0%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLD 83
S LGA+L L GR NL + C + + L++T +L S + ++++ ++ YGKLD
Sbjct: 73 SHLGARLVLAGRKEANLMRTKDSCMQTGNEEALTVTGELRDGSYRKHLVEQAMEEYGKLD 132
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 143
+LVNNAG+I G+IEN+SL YD +M+ NVRS+++LT LAVPHL+E+KG G+
Sbjct: 133 ILVNNAGVISLGSIENSSLEDYDTMMDVNVRSVFHLTSLAVPHLIETKGNIVNVSSVNGL 192
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 203
R+F GVL+Y +SKA++D FTRC ALELAPKGVRVN VNPGV +TELQ+RGGLS+E YA F
Sbjct: 193 RAFAGVLSYCMSKAALDHFTRCTALELAPKGVRVNSVNPGVTITELQKRGGLSDEAYANF 252
Query: 204 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHAMCPR 254
LER+K THALGRPG+ E+A +IAFLASD +S ITGA++PVDGGRHAMCPR
Sbjct: 253 LERSKMTHALGRPGEASEIAESIAFLASDASSFITGATLPVDGGRHAMCPR 303
>UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p -
Drosophila melanogaster (Fruit fly)
Length = 255
Score = 220 bits (537), Expect = 3e-56
Identities = 108/254 (42%), Positives = 158/254 (62%), Gaps = 3/254 (1%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
M+ + KVV L++ GA L+L GRNV NL+ K K + A
Sbjct: 5 MSLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSL-KGTQAEIVVA 63
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+TK++D I+++T+ +G++DVLVNNAGI+ G + + + ++D ++NTN+R + LT
Sbjct: 64 DVTKDADA--IVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLT 121
Query: 121 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
+PHLL++KG GIR F G L+Y +SKA++DQFT+ VALE+AP+GVRVN V
Sbjct: 122 KAVLPHLLKTKGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSV 181
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
NPG ++T + R G+ +E+Y L+R +H +GR G EVA +AFLAS AS TGA
Sbjct: 182 NPGFVVTNIHRNIGIVDEEYNGMLQRAINSHPMGRVGDVTEVAEAVAFLASSKASFTTGA 241
Query: 241 SVPVDGGRHAMCPR 254
P+DGG+H + PR
Sbjct: 242 LFPIDGGKHNLTPR 255
>UniRef50_Q15ER8 Cluster: U2 snRNP splicing factor small
subunit-like protein; n=3; Bilateria|Rep: U2 snRNP
splicing factor small subunit-like protein - Schistosoma
mansoni (Blood fluke)
Length = 265
Score = 217 bits (529), Expect = 3e-55
Identities = 116/264 (43%), Positives = 156/264 (59%), Gaps = 10/264 (3%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST----- 55
++ + KV +KLGA ++L R+ L++ + C + +
Sbjct: 2 ISLSRKVAIITGASSGIGRATAILFAKLGACVALIARDKSRLEETRQACIQISHPDVYEK 61
Query: 56 -----LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 110
L I ADL + +IEK + I+H+ +LD+LVNNAG + T E+ ++A+Y+ LM
Sbjct: 62 HKEPFLCIEADLAETCEIEKAYRLAINHFHQLDILVNNAGCMIRDTAESFNVAEYEHLMK 121
Query: 111 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL 170
NV + LT LA+P L SKG G RSFPGV++Y ISKA++DQFTRC AL+L
Sbjct: 122 VNVTAAITLTNLAIPDLAASKGSIVNVSSVCGKRSFPGVMSYCISKAALDQFTRCTALDL 181
Query: 171 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 230
APKG+RVN V P VI+TEL RR G+SE Y FL R ETHALGR G +EVA IAFL+
Sbjct: 182 APKGIRVNSVYPAVIVTELHRRSGMSENDYEKFLSRANETHALGRTGTVEEVAQAIAFLS 241
Query: 231 SDLASNITGASVPVDGGRHAMCPR 254
S +S TG + +DGGR MCPR
Sbjct: 242 SSASSFTTGNLLMLDGGRSIMCPR 265
>UniRef50_UPI0000E47988 Cluster: PREDICTED: similar to short-chain
dehydrogenase; n=3; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to short-chain dehydrogenase -
Strongylocentrotus purpuratus
Length = 269
Score = 199 bits (485), Expect = 6e-50
Identities = 111/257 (43%), Positives = 149/257 (57%), Gaps = 8/257 (3%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSI 58
F GKVV + GA L+L GR+ L+K ++DC L+I
Sbjct: 4 FVGKVVLITGASSGIGAETAVHFAAEGAGLALVGRDEGRLEKTAQDCMAKGLAKDKVLTI 63
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN-TSLAQYDRLMNTNVRSIY 117
AD+ E D+++I++ TI ++G+LDVLVNNAG + + + T + +D L+ NVRS+
Sbjct: 64 KADMCVEEDVKRIVESTITYFGRLDVLVNNAGQAKLDLLRSETVMENFDDLLKLNVRSVV 123
Query: 118 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
LT LAVPHL+ SKG G R +YNI +A+ DQFTRC A++LAPKGVRV
Sbjct: 124 QLTNLAVPHLITSKGSVVNVSSLAGKRVAHMSFSYNILRAATDQFTRCCAVDLAPKGVRV 183
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
N VNPG I T L G+ EQ E + H LGR G+P +VA+ I FLAS+ AS I
Sbjct: 184 NAVNPGAIKTPLLTGFGIPAEQIE---EVCAKMHPLGRIGQPTDVASAIKFLASNAASFI 240
Query: 238 TGASVPVDGGRHAMCPR 254
TG ++ +DGGRHA C R
Sbjct: 241 TGETLSIDGGRHAYCAR 257
>UniRef50_UPI0000E499EA Cluster: PREDICTED: similar to
ENSANGP00000021339; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to ENSANGP00000021339
- Strongylocentrotus purpuratus
Length = 242
Score = 196 bits (477), Expect = 6e-49
Identities = 98/231 (42%), Positives = 147/231 (63%), Gaps = 5/231 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSITADLTKESDIEKIIKKTIDHYGK 81
+ LG +L+LTGRN+E LQ+V+ +C + L I AD E+D+++ ++TI + +
Sbjct: 6 ASLGCRLALTGRNMETLQEVTNECIRRGLDKNKILMIQADFELEADVKRTAEETIQKFNQ 65
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 141
+DVLVNNAG++ G++E SL +D++ NVR+ LT L P L+++KG
Sbjct: 66 IDVLVNNAGVLTAGSVETVSLESFDKIFAVNVRAPLQLTQLLAPQLIKTKGTVVNVSSVV 125
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRG-GLSEEQY 200
G S P L Y++SK ++D TR +A ELAP GVRVN VNPG I+T + +R G+++E+
Sbjct: 126 GKVSMPDFLIYSMSKTALDHMTRSIAEELAPHGVRVNAVNPGAIVTPIIKRSFGMTDEET 185
Query: 201 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHAM 251
A F E+ K HA+ R G DEV+ TIAF+AS+ +S TG +V +DGG H +
Sbjct: 186 AQFFEKMKRNHAMRRTGTVDEVSRTIAFMASNDSSFTTGETVGIDGGCHLL 236
>UniRef50_Q9NBB5 Cluster: 3-dehydroecdysone 3alpha-reductase; n=1;
Spodoptera littoralis|Rep: 3-dehydroecdysone
3alpha-reductase - Spodoptera littoralis (Egyptian
cotton leafworm)
Length = 249
Score = 182 bits (444), Expect = 6e-45
Identities = 97/248 (39%), Positives = 146/248 (58%), Gaps = 7/248 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITAD 61
FA KVV K GA ++ GRN L++V C + A+ L+I AD
Sbjct: 2 FANKVVLVTGGSSGIGAATVEAFVKEGASVAFVGRNQAKLKEVESRCQQHGANILAIKAD 61
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLT 120
++K+ + + I+++T+D +GKLDVLVNNAGI+ ++ E T + +D MNTN+R + +T
Sbjct: 62 VSKDEEAKIIVQQTVDKFGKLDVLVNNAGILRFASVLEPTLIQTFDETMNTNLRPVVLIT 121
Query: 121 MLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
LA+PHL+ +KG I PG+++Y++SKA++D FT+ ALELAP GVRVN
Sbjct: 122 SLAIPHLIATKGSIVNVSSILSTIVRIPGIMSYSVSKAAMDHFTKLAALELAPSGVRVNS 181
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
VNPG +LT++ G S + LE T LG+ + +E+A I +LASD A ++TG
Sbjct: 182 VNPGPVLTDIAAGSGFSPD----LLEDTGAHTPLGKAAQSEEIADMIVYLASDKAKSVTG 237
Query: 240 ASVPVDGG 247
+ +D G
Sbjct: 238 SCYIMDNG 245
>UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chain
dehydrogenase; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to short-chain dehydrogenase -
Strongylocentrotus purpuratus
Length = 250
Score = 177 bits (432), Expect = 2e-43
Identities = 97/251 (38%), Positives = 140/251 (55%), Gaps = 7/251 (2%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST----LSITA 60
GKV +++G +L+LTGR+ E L+ V K C + + L I A
Sbjct: 3 GKVALITGSSSGIGAGIAERFAEIGCRLALTGRDAEKLKDVGKSCCERGLSEKEILVIAA 62
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
DLT++ D+E+I KTI+ +G+LD+L+NNAG G + + +D +M N+RS YL+
Sbjct: 63 DLTEDEDLERIFSKTIEKFGRLDILINNAGRPAKGRFHDLQMTFFDDVMRLNLRSAIYLS 122
Query: 121 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
LA+P+L ESKG + Y+ISK ++DQFT+ +A+EL P GVRVN +
Sbjct: 123 KLAIPYLKESKGCVVNMSSVASKTTCDYNPTYSISKVALDQFTKSLAVELGPYGVRVNSL 182
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
NPGVILT L R G S+ Q + +K H +GR G DEV +L SD + +TG
Sbjct: 183 NPGVILTPLYRNLGKSDAQVITW---SKSMHPIGRHGTVDEVVKATEYLVSDASRCVTGT 239
Query: 241 SVPVDGGRHAM 251
+ +DGGR M
Sbjct: 240 LLSIDGGRFLM 250
>UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Pasteurellaceae|Rep: Short-chain
dehydrogenase/reductase SDR - Actinobacillus
succinogenes 130Z
Length = 248
Score = 155 bits (377), Expect = 8e-37
Identities = 86/223 (38%), Positives = 124/223 (55%), Gaps = 3/223 (1%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
++K GA + + GRN L++ ++ + + AD+ K DI +++ + + +GKLD+
Sbjct: 26 MAKDGANVVIIGRNEATLEE---SAEQHENITYLVADVLKSEDIARVLTEIQEEFGKLDI 82
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 144
+VNNAGI IEN +LA +DR NVR++ +T A+P+L SKG
Sbjct: 83 VVNNAGIAPMTPIENINLADFDRTFALNVRAVIDVTAQAIPYLKASKGNIVNIISGLVHN 142
Query: 145 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 204
PG Y SKA+V TR A ELA G+RVNCV+ G T + G SEEQ A+
Sbjct: 143 PMPGNCIYTASKAAVLSLTRTWAKELAAYGIRVNCVSVGAANTSIHDALGFSEEQMNAYK 202
Query: 205 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ LGR G+PDE+A +AFLAS+ A +TG+ VDGG
Sbjct: 203 QAVSSAVPLGRFGEPDEIAPIVAFLASEHARYVTGSDYGVDGG 245
>UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;
n=5; Caenorhabditis|Rep: Dehydrogenases, short chain
protein 14 - Caenorhabditis elegans
Length = 279
Score = 149 bits (362), Expect = 5e-35
Identities = 90/258 (34%), Positives = 141/258 (54%), Gaps = 13/258 (5%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSI 58
F+GKV L++ GA++++TGRN + L++ ++ K LSI
Sbjct: 4 FSGKVALVTGSSNGIGRATAVLLAQEGAKVTITGRNADRLEETRQEILKSGVPEDHVLSI 63
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTIE-NTSLAQYDRLMNTNVR 114
DL E ++++ TI +G+LD+LVNNAG + G + + ++ YDR+M N+R
Sbjct: 64 ATDLATEKGQDELVNSTIQKFGRLDILVNNAGAAFNDDQGRVGVDQDVSVYDRIMQINMR 123
Query: 115 SIYYLTMLAVPHLLESKGXXXXXXXX-XGIRSFPGVLAYNISKASVDQFTRCVALELAPK 173
S+ LT A HL+++KG G ++ P + Y +SKA++DQ+TR A++L
Sbjct: 124 SVVTLTQKAKEHLVKAKGEVVNVSSIGAGPQAQPTFMYYAMSKAALDQYTRSAAIDLIQY 183
Query: 174 GVRVNCVNPGVILTELQRRGGL---SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 230
GVRVN V+PG ++T G+ E+Y F+E KE G+ G+P ++A IAFLA
Sbjct: 184 GVRVNSVSPGAVVTGFGEAMGMPADMHEKYGHFMESRKECIPCGKMGQPIDIANIIAFLA 243
Query: 231 S-DLASNITGASVPVDGG 247
L+S I G S+ DGG
Sbjct: 244 DRKLSSYIIGQSIVADGG 261
>UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1;
Rhizobium sp. NGR234|Rep: Putative uncharacterized
protein - Rhizobium sp. (strain NGR234)
Length = 244
Score = 147 bits (355), Expect = 4e-34
Identities = 79/193 (40%), Positives = 115/193 (59%), Gaps = 1/193 (0%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 116
SI+ D+T E + + I K + G+LD+L+NNAG+ E+G++E TSL Q+ RL++TN+ SI
Sbjct: 49 SISLDVTDEGNWTRAISKVVSAAGRLDILINNAGVRESGSVEETSLEQWRRLIDTNLTSI 108
Query: 117 YYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 175
+ AVP + ++ G GIR ++AY+ SK+ + T +AL+LA +
Sbjct: 109 FLGCRAAVPAIRQAGGGAIVNVGSITGIRGTENMVAYSASKSGITSMTSSLALDLASDNI 168
Query: 176 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
RVN V P I T + S + A H +GR G+PDEVA+ IAFLASD +S
Sbjct: 169 RVNAVCPAAIRTRMVTNWLNSSQDTDAAEAAVLAKHPIGRIGRPDEVASVIAFLASDDSS 228
Query: 236 NITGASVPVDGGR 248
+TG S+PVDGGR
Sbjct: 229 FMTGMSIPVDGGR 241
>UniRef50_Q67RW6 Cluster: Ketoreductase; n=5; Bacteria|Rep:
Ketoreductase - Symbiobacterium thermophilum
Length = 241
Score = 143 bits (346), Expect = 4e-33
Identities = 83/222 (37%), Positives = 120/222 (54%), Gaps = 3/222 (1%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 85
++ GA++ +TGR E L++ +TAD+T SD +++++ +G++DV+
Sbjct: 19 ARRGAKVLITGRRPEPLRETEAAAPGIRG---VTADVTVASDARRVVEEAAKLWGRIDVV 75
Query: 86 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS 145
VNNAG+ +G E +L TNV L A+P L ES+G G ++
Sbjct: 76 VNNAGMFASGPFEKVGAETAAQLFATNVFGPINLVREALPWLKESRGAIINVSSTYGHKA 135
Query: 146 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 205
V Y SKA++D TRC ALELAP G+RVN V PG T + R GL E+ A+ E
Sbjct: 136 AANVAHYAASKAALDHLTRCWALELAPYGIRVNAVAPGPTETPILSRSGLPEDVVASIKE 195
Query: 206 RTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
K LGR G+PD+VAA I LA+ + +TG + VDGG
Sbjct: 196 AEKRQIPLGRRGEPDDVAAWIVALAAPGSHWLTGQVIGVDGG 237
>UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Candidatus Nitrosopumilus maritimus
SCM1|Rep: Short-chain dehydrogenase/reductase SDR
precursor - Candidatus Nitrosopumilus maritimus SCM1
Length = 269
Score = 140 bits (340), Expect = 2e-32
Identities = 78/250 (31%), Positives = 141/250 (56%), Gaps = 10/250 (4%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
++ +GKV LS+ GA +++TG+ E L+KVS + +++ +I A
Sbjct: 23 LSLSGKVALVTGGSRGIGFATAKVLSENGANVAITGKVQERLEKVSSE---ISNSFAIVA 79
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+ K D++ IKK ++ +G+LD+LVNNAG+ + + +++ +++ N+ + +
Sbjct: 80 DVRKTEDVKNAIKKIVEKFGRLDILVNNAGVFPKIKKLHEIDDEEWNEVLDVNLTGQFRV 139
Query: 120 TMLAVPHLLESKGXXXXXXXXXGIRSFPG--VLAYNISKASVDQFTRCVALELAPKGVRV 177
T A+PHL ++ G G++++ G AY+ +KA++ T+C ALE + +RV
Sbjct: 140 TKEAIPHLQKTSGSIINISSDAGLKAYQGFNADAYSATKAALIVLTKCWALEYSKDKIRV 199
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
NC+ PGV+ T++ + + ++ F+ H LGR G+P+EVA + + ASD A+
Sbjct: 200 NCICPGVVDTDM-TKPFVKTQKDRDFM---NAEHPLGRIGEPEEVAKAVLYFASDDAAWT 255
Query: 238 TGASVPVDGG 247
TGA + VDGG
Sbjct: 256 TGAILAVDGG 265
>UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Rep:
Blr1409 protein - Bradyrhizobium japonicum
Length = 266
Score = 139 bits (336), Expect = 7e-32
Identities = 80/249 (32%), Positives = 136/249 (54%), Gaps = 7/249 (2%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITA 60
+ GKV L++LGA++ ++ R + ++V+ + + I
Sbjct: 16 DLTGKVAIVTGSSRGIGRSSAELLARLGAKVVVSSRKADACKEVADGINAAGGDAIVIPC 75
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYL 119
++ +++++E +I HYGK+D+LV NA + G + + + +D++M +NV+S +L
Sbjct: 76 NIARKAEVEALIAGATTHYGKIDILVCNAAVNPYYGPLLDITDEAFDKIMGSNVKSNIWL 135
Query: 120 TMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
+ LA+P + E G G+R + AY ISKA+ R +A E PKGVRVN
Sbjct: 136 SALAIPQMAERGNGSVIIISSIGGLRGSTVIGAYGISKAADFALCRSLAGEWGPKGVRVN 195
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
C+ PG++ T+ R L E++ A L+R T L R G+PDE+A +A+LASD +S +T
Sbjct: 196 CIAPGLVKTDFAR--ALWEDE--ALLKRRTATTPLRRIGEPDEIAGAVAYLASDASSFMT 251
Query: 239 GASVPVDGG 247
G ++ +DGG
Sbjct: 252 GQTIVIDGG 260
>UniRef50_A1C190 Cluster: Oxidoreductase; n=10; Streptomyces|Rep:
Oxidoreductase - Streptomyces echinatus
Length = 295
Score = 137 bits (332), Expect = 2e-31
Identities = 78/220 (35%), Positives = 122/220 (55%), Gaps = 5/220 (2%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++ + GR L++ ++ ++ AD+T + ++ ++ +G++DVLVNN
Sbjct: 74 GARVLVVGRTPGTLEETARH---HPGIRALPADITAPDGPDTVVSAALERFGRIDVLVNN 130
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX--XXXXXXGIRSF 146
A + GT++ A D + TN+R+ LT A+P L +S G G R++
Sbjct: 131 AALGIAGTLDTLDPADLDAQLATNLRAPMLLTRRALPALEKSSGTVVNLSTAGSLGRRAW 190
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 206
PG+ Y +K ++D TR A+ELAP+G+RV + PGVI T + R G SEEQYAAFL+
Sbjct: 191 PGMSVYGATKTALDFLTRTWAVELAPRGIRVVGLAPGVIDTGMATRNGASEEQYAAFLDG 250
Query: 207 TKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDG 246
+ GR G+P+E+A +A LA LA G + VDG
Sbjct: 251 IRSRVPAGRVGRPEEIAWWVARLADPLAGYAHGTVLAVDG 290
>UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep:
Bll5898 protein - Bradyrhizobium japonicum
Length = 256
Score = 137 bits (331), Expect = 3e-31
Identities = 79/219 (36%), Positives = 115/219 (52%), Gaps = 4/219 (1%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA + L GR L +V + + AD+T +D+E ++ + +G++D+LVNN
Sbjct: 31 GAIVVLNGRRESKLAEVGAELGTDRCMIR-PADVTIAADVESLVADAVRRFGRIDILVNN 89
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 148
AG + + Q+ L NV + Y+T A+PHL+ES G G+ G
Sbjct: 90 AGTGALIDFLGSPIQQWRDLFAVNVDGVLYMTRAALPHLIESGGSIVNVSSLSGLGGDRG 149
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 208
+ YN +K +V TR +ALE P+GVR+N V P + LT L EQY L +
Sbjct: 150 LSFYNATKGAVSNLTRSLALEFGPRGVRINAVCPSLTLTHLTMP---ILEQYPELLAKLV 206
Query: 209 ETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LGR + +EVA+ IAFLASD AS + G ++PVDGG
Sbjct: 207 GRIPLGRAAQSEEVASVIAFLASDDASFVNGVNLPVDGG 245
>UniRef50_Q7CZN0 Cluster: AGR_C_2317p; n=3; Proteobacteria|Rep:
AGR_C_2317p - Agrobacterium tumefaciens (strain C58 /
ATCC 33970)
Length = 292
Score = 137 bits (331), Expect = 3e-31
Identities = 85/247 (34%), Positives = 122/247 (49%), Gaps = 5/247 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQ-LSLTGRNVENLQKVSKDCDKFASTLSITAD 61
F+G+VV + GA + +TGRN NL K A + +D
Sbjct: 45 FSGQVVVVTGGSTGIGFSVAKLFLEGGASTVYVTGRNSANLDAAVAKLGKGA--IGFVSD 102
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
+ K SD+E++ + K+DVLV NAGI E + T A YDR+ + NV+ ++Y
Sbjct: 103 VAKLSDLEQLKSRLEADGRKVDVLVANAGIAENNDLGETHEALYDRIFDINVKGVFYTVQ 162
Query: 122 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
+P +L G G + + AYN SKA+V F R A +L +G+RVN V+
Sbjct: 163 TLLP-VLRDGGSIVLTGSIVGNKGMERLSAYNASKAAVRSFARSFANDLKGRGIRVNTVS 221
Query: 182 PGVILTELQRRG-GLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PGV T + G + +E+ A F K+ +GR PDE+A + FLAS AS ITG
Sbjct: 222 PGVTRTPIMENGLKMDDEKIAGFKAYLKDAAPIGRMADPDEIAEAVLFLASSKASYITGV 281
Query: 241 SVPVDGG 247
+ VDGG
Sbjct: 282 ELSVDGG 288
>UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Clostridium beijerinckii NCIMB 8052
Length = 246
Score = 137 bits (331), Expect = 3e-31
Identities = 79/248 (31%), Positives = 129/248 (52%), Gaps = 8/248 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLT-GRNVENLQKVSKDCDKFAS-TLSIT 59
N GKV LS LGA++ + N ++V ++ K ++I
Sbjct: 3 NLEGKVAIITGASRGIGSAIARQLSALGAKVVVNYSNNAVKAEEVVEEITKSGEQAVAIK 62
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
AD++ D+EK+ +TI +G++D+L+NNAG+I + + + ++D+L N NV+ Y+
Sbjct: 63 ADVSNIKDVEKLFSETITKFGRVDILINNAGVILYKLLSDVTEEEFDKLFNINVKGTYFA 122
Query: 120 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
A+ H +E+ G FP Y +K +V+Q TR +A E PK + +N
Sbjct: 123 CQQAMKH-MENNGRIINFSTSVVGSMFPTYSVYAATKGAVEQITRQLAKEFGPKKITINA 181
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
V PG I TEL G E+ +E ++ ++ GR G+PD++A TI FL SD A ITG
Sbjct: 182 VAPGPINTELFNVGKTDEQ-----IEAIRQMNSFGRIGEPDDIANTIEFLVSDKAQWITG 236
Query: 240 ASVPVDGG 247
++ ++GG
Sbjct: 237 QTLRINGG 244
>UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Chloroflexus|Rep: Short-chain
dehydrogenase/reductase SDR - Chloroflexus aggregans DSM
9485
Length = 256
Score = 137 bits (331), Expect = 3e-31
Identities = 87/258 (33%), Positives = 128/258 (49%), Gaps = 12/258 (4%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 59
M F GKV L++ GA + + R+ + + + + L++
Sbjct: 1 MEFQGKVAIVTGGAQGIGRATALALAREGAAVVIADRDAAATTALVEGINAWGGRALAVI 60
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
AD++ ESD +I T+ +G +D+LVNNAGI + GTIE+T+L + ++N N+ ++ +
Sbjct: 61 ADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVFLV 120
Query: 120 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
+ +P L G G+R+ G AY SK V TR +AL+ AP G+RVN
Sbjct: 121 SRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDGAPDGIRVN 180
Query: 179 CVNPGVILTELQRRGGL------SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 232
CV PG+I T L R +E+ AF R LGR G P+EVAA I L S
Sbjct: 181 CVCPGLIDTSLLRANAALVNTQRPDEELRAFARRV----PLGRLGTPEEVAAVILCLLSP 236
Query: 233 LASNITGASVPVDGGRHA 250
A +TGA + DGG A
Sbjct: 237 TAGYLTGAVITADGGWEA 254
>UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1;
Sarcoptes scabiei type suis|Rep: Putative
uncharacterized protein - Sarcoptes scabiei type suis
Length = 304
Score = 136 bits (330), Expect = 4e-31
Identities = 85/260 (32%), Positives = 134/260 (51%), Gaps = 9/260 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS----TLS 57
+F+GKV ++ GA++ +TGR+ L+KV+ + +K L
Sbjct: 38 DFSGKVALVTGSSSGIGAAIALQFAQYGAKVCITGRDSNALEKVAGEIEKATGGKHRPLK 97
Query: 58 ITADLTKESDIE-KIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQ-YDRLMNTNVR 114
I L ++ + ++I +T++ +G+LD LVNNAG G + + +L YD++ + NVR
Sbjct: 98 IIGGLVEDRQLPVRLINETVNEFGRLDFLVNNAGGSTAHGKLTDENLMDSYDKVFDLNVR 157
Query: 115 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 174
S+ +L +A PHL ++KG I P L Y+ SKA++D T+C+A+E G
Sbjct: 158 SVLHLCQVAKPHLEKTKGNIINISSIAAI--VPYSLIYSPSKAALDMMTKCLAIEYGDIG 215
Query: 175 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
VRVN +NPG + T R G+ + Y +R L DE+A +FLASD A
Sbjct: 216 VRVNSINPGPVRTGFLRSMGMQMDNYDELYDRYSSNTLLNFVPYGDEIANLASFLASDDA 275
Query: 235 SNITGASVPVDGGRHAMCPR 254
N+TG+ V D G M P+
Sbjct: 276 KNLTGSIVVSDTGCMLMKPK 295
>UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein; n=3;
Proteobacteria|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family protein - Erythrobacter
sp. NAP1
Length = 267
Score = 134 bits (325), Expect = 2e-30
Identities = 81/249 (32%), Positives = 127/249 (51%), Gaps = 9/249 (3%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
FAGK V GA + + RN E KV+ D TL+ D+
Sbjct: 7 FAGKTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADTLDA-DRTLTCPGDV 65
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ +I+ KT++ +G LD LVNNAG+ + + T + DR+++ NV+ + YL
Sbjct: 66 SSSDFANEIVAKTVERFGGLDCLVNNAGVGGSSMLHKTDDEEIDRIIDINVKGVIYLCRA 125
Query: 123 AVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
A+PHL +S+ G GI + YN SK ++ TR +A ++ G+RVN
Sbjct: 126 AIPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTRGLAQQIGGMGIRVN 185
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
+NP + +++ G L+ + A LE +GR G+P+++AA AFLAS+ A+ IT
Sbjct: 186 AINPSITRSDMV-DGILAND---ALLEAFMRRVPMGRIGEPEDIAAACAFLASEDAAFIT 241
Query: 239 GASVPVDGG 247
G ++PVDGG
Sbjct: 242 GVNLPVDGG 250
>UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Geobacter metallireducens (strain GS-15 / ATCC
53774 / DSM 7210)
Length = 255
Score = 134 bits (323), Expect = 3e-30
Identities = 76/225 (33%), Positives = 123/225 (54%), Gaps = 5/225 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA L L RN ++ KV+ + K L++ D+ K DI+ ++ K I +G +D
Sbjct: 30 LAEAGANLVLASRNEASMAKVASEVTSKGVQCLTVKTDMLKADDIQAMVDKGIAQFGTID 89
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 142
+LVNNAGI N + +D +++TN++ + + + ++++K G G
Sbjct: 90 ILVNNAGINLVKPFVNLTEEDWDSVVDTNLKGYFLCSQVVGREMIKNKNGCVINNASVFG 149
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+R FP + +Y SK V Q TR +A+E A +RVNC+ PG I+TE+ +R E
Sbjct: 150 LRGFPNIASYIASKGGVVQLTRGLAVEWARHNIRVNCIAPGYIVTEMAKR---DIETNPK 206
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LE+ + R G+P EVA + FLAS+ +S +TG V +DGG
Sbjct: 207 ILEQNLLKIPMKRGGQPREVADVVVFLASEASSYMTGQIVSMDGG 251
>UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn)
reductase precursor; n=1; Rhodopseudomonas
palustris|Rep: Putative 3-oxoacyl-(Acyl carrier ptn)
reductase precursor - Rhodopseudomonas palustris
Length = 262
Score = 133 bits (322), Expect = 4e-30
Identities = 83/248 (33%), Positives = 123/248 (49%), Gaps = 5/248 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-IT 59
M F GKV L++ GA + L+ + + L + ++ A +S +
Sbjct: 1 MRFNGKVAVVTAAASGIGAATAARLAREGAYVYLSDIDQDALGRQAESLVDVAERISTVV 60
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
AD+T + +I G+LD+L+NNAG+ G I + + R+ V SI++
Sbjct: 61 ADVTVPEQVSALIDGAARERGRLDILINNAGMGAFGRITEVTPEAWHRVFGICVDSIFHA 120
Query: 120 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+ A+PHL++++G G+ G AYN +K +V TR +AL+ + G+RVN
Sbjct: 121 SRAAIPHLIKARGTIVNTASISGLFGDYGFAAYNAAKGAVINLTRNMALDYSRDGLRVNA 180
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
V PG+I T L L AA + LGR G P+EVA IAFLASD AS ITG
Sbjct: 181 VCPGLIATPL----SLKLRDNAAVMAEYDRLIPLGRAGSPEEVAGAIAFLASDDASYITG 236
Query: 240 ASVPVDGG 247
+ VDGG
Sbjct: 237 VAFAVDGG 244
>UniRef50_Q89K11 Cluster: Oxidoreductase; n=6; Proteobacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 281
Score = 132 bits (318), Expect = 1e-29
Identities = 73/219 (33%), Positives = 121/219 (55%), Gaps = 3/219 (1%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++ +TGRN E L +K+ A L++ AD T + E I++ + +GK D++ N
Sbjct: 53 GAKVVITGRNKETLAAAAKELGPNA--LAVVADATDIAATEAAIRQGAEKFGKFDIVFAN 110
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 148
AGI + + +L ++++++TN+ +++ A+PHL ++ + PG
Sbjct: 111 AGIPGSTPLGAATLEVFEKVISTNLTGVFFTVQSALPHLNDN-ASIILNGSVISVLGIPG 169
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 208
AY +KA V R +A EL+P+G+RVN V PG I T + + E AF +R
Sbjct: 170 YSAYGAAKAGVRAMARIMASELSPRGIRVNVVAPGAIRTPIWGAAIATPEAEKAFEKRIA 229
Query: 209 ETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ LGR G+PD ++ T+ FLASD +++I G + VDGG
Sbjct: 230 LSTPLGRIGEPDHISKTVLFLASDDSAHIQGQEIFVDGG 268
>UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: FabG protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 248
Score = 132 bits (318), Expect = 1e-29
Identities = 77/223 (34%), Positives = 120/223 (53%), Gaps = 3/223 (1%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
L++ GA++ + GR + LQ+ + A + AD+ K+ D++KI+++ YG LD+
Sbjct: 26 LAQEGAKVLVVGRTEKTLQETTALHPNIAYAV---ADIEKDDDVQKIVQQLNQKYGGLDI 82
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 144
L+NNAG I + +YD++ NVR++ LT+ +P L KG
Sbjct: 83 LINNAGWAPVTPISQVKIEEYDKVFGINVRALVNLTLQCLPMLKARKGNIINMSSAICRN 142
Query: 145 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 204
P + Y +KA+V+ FT+ A EL GVRVN ++ G I T + + LS + +
Sbjct: 143 HLPNMSMYAGTKAAVEIFTKIWAKELGADGVRVNSISVGPIETPIYDKTDLSNDGIQDHI 202
Query: 205 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+R ++T LG GK ++VA AFLASD A ITG+ VDGG
Sbjct: 203 DRIRKTIPLGAFGKSEDVANVTAFLASDEARFITGSDYSVDGG 245
>UniRef50_Q1IK61 Cluster: Short-chain dehydrogenase/reductase SDR;
n=56; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Acidobacteria bacterium
(strain Ellin345)
Length = 252
Score = 131 bits (317), Expect = 1e-29
Identities = 80/219 (36%), Positives = 118/219 (53%), Gaps = 3/219 (1%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA + LTGR L + + S ++I D + SD+EKI+ + + GKLD+L N
Sbjct: 33 GAFVFLTGRREPELLAAANELGP--SAIAIRTDSSLISDVEKILARIRETKGKLDILFAN 90
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 148
AGI E + + +D++ +TNV+ I +L A+P L+ S I+ P
Sbjct: 91 AGIGEFLPLGVITEEHFDKIFSTNVKGIVFLVQKALP-LMPSGSSIVLNASIASIKGMPA 149
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 208
Y+ SKA++ F R +L + +RVN V+PGVI T GLS+++ FL+
Sbjct: 150 FSIYSASKAALRSFARSWTTDLRRQQIRVNAVSPGVISTPGYDGLGLSKQEMETFLKTNA 209
Query: 209 ETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
ET LGR G PDEVA + FL+SD +S I+G + VDGG
Sbjct: 210 ETIPLGRVGTPDEVAKAVVFLSSDESSYISGIELFVDGG 248
>UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 131 bits (317), Expect = 1e-29
Identities = 87/259 (33%), Positives = 133/259 (51%), Gaps = 14/259 (5%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC----DKFASTLSI 58
F KV L+ GA++++TGRN E L++ + L +
Sbjct: 4 FTDKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGNVLVV 63
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI----IETGTIENTSLAQYDRLMNTNVR 114
D+T+ES E +IK T+D +GK+D+LVNNAG + + N S+ Y + NV+
Sbjct: 64 VGDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQ 123
Query: 115 SIYYLTMLAVPHLLESKGXXXXXXXX-XGIRSFPGVLAYNISKASVDQFTRCVALELAPK 173
S+ +T A PHL +++G G + Y+I+KA++DQ+TR A++L P+
Sbjct: 124 SVIEMTQKARPHLAKTQGEIVNISSIGAGPAAQVASPYYSIAKAALDQYTRTAAIDLVPE 183
Query: 174 GVRVNCVNPGVILTELQR-RGGLSEEQYAAF---LERTKETHALGRPGKPDEVAATIAFL 229
G+RVN V+PG + T GL+EE+ AF L +E G P+++A IAFL
Sbjct: 184 GIRVNSVSPGAVSTGFSAVSRGLTEEKSKAFYDYLGAQRECIPRGFCAVPEDIAKVIAFL 243
Query: 230 ASDLASN-ITGASVPVDGG 247
A ASN I G ++ DGG
Sbjct: 244 ADRNASNYIIGQTIVADGG 262
>UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Methanoculleus marisnigri
(strain ATCC 35101 / DSM 1498 / JR1)
Length = 249
Score = 131 bits (317), Expect = 1e-29
Identities = 81/227 (35%), Positives = 121/227 (53%), Gaps = 11/227 (4%)
Query: 29 GAQLSLTGRNV-ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
G ++ ++GRN E + V++ + + I AD+T E D+ ++ KT++ +G+LDV V
Sbjct: 30 GGKVVVSGRNEKEGARIVNEIKEAGGEVIFIRADVTVEDDVRNLVAKTVEAFGRLDVFVA 89
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF- 146
N+G+ G ++DR+++ N++ I+ AV +L+ +G I SF
Sbjct: 90 NSGVGSLGDPHEVETEEWDRVLDVNLKGIFLCDKYAVQQMLK-QGQGGAIVNTGSIHSFV 148
Query: 147 --PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 204
GV AY +K V TR + A +G+R N V PG I T L L E Y
Sbjct: 149 AKQGVTAYGAAKGGVAMLTRTLGTSYAAQGIRANFVAPGYIDTPL--LAALPREAY---- 202
Query: 205 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHAM 251
E K+ H +GR G+P EVA + FLASD ASNITG S+ VDGG A+
Sbjct: 203 EELKKLHPIGRLGRPMEVAKAVTFLASDDASNITGTSLLVDGGYTAV 249
>UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1;
Thermobifida fusca YX|Rep: Short-chain alcohol
dehydrogenase - Thermobifida fusca (strain YX)
Length = 267
Score = 131 bits (316), Expect = 2e-29
Identities = 72/229 (31%), Positives = 121/229 (52%), Gaps = 6/229 (2%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA + RN + + D T L++TAD++ +D E++ T++H+G++D++
Sbjct: 33 GASVVCVDRNADAAHSAADDIAAAGGTALALTADVSSAADAERMTTTTLEHFGRIDIVFA 92
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 146
NAGI +G T+ ++DR++ N++ ++ + A+PH++E + G G+
Sbjct: 93 NAGIPGSGDAHTTTEEEWDRVIAINLKGVWLTSKYALPHMVERRSGVITNQASVGGLIGI 152
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL----QRRGGLSEEQYAA 202
PG+ Y +K V TR +A AP +RVN + PG + T L +++ GL+
Sbjct: 153 PGIFPYAAAKGGVISMTRQMAAAYAPHNIRVNAICPGGVYTPLVELSRQKRGLTASSVEE 212
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHAM 251
+ LGR G +E+A+ FLASD A+ ITG PVDGGR A+
Sbjct: 213 ANAIAARNYPLGRLGTVEEIASLALFLASDEAAWITGGIYPVDGGRGAV 261
>UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein; n=4;
Bacteria|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family protein - Psychroflexus
torquis ATCC 700755
Length = 269
Score = 130 bits (315), Expect = 3e-29
Identities = 72/219 (32%), Positives = 114/219 (52%), Gaps = 5/219 (2%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA + +TGR+ E + K S++ I AD+ S I+ ++ + +GK+DVL N
Sbjct: 48 GATVVITGRDSEKVAKASQEL----GVKGIVADVKSLSAIDDLVAQVKSDFGKVDVLFVN 103
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 148
AGI + + S +D M+ N + ++ T +P +L P
Sbjct: 104 AGIFQPAPVGQISEEMFDHQMSINFKGAFFTTEKFLP-ILNDGASVINLSSVNAYTGMPN 162
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 208
Y SKA+++ +TR A ELAP+ +R+N VNPG + T + + G+ EEQ F E +
Sbjct: 163 TAVYAASKAALNAYTRTAATELAPRKIRINSVNPGPVSTPIYGKTGMEEEQLNGFAEAMQ 222
Query: 209 ETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
L R G+P+++A ++FLASD AS ITG+ +DGG
Sbjct: 223 NRIPLKRFGQPEDIAKLVSFLASDDASFITGSEYNIDGG 261
>UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
Short-chain dehydrogenase/reductase SDR - Candidatus
Nitrosopumilus maritimus SCM1
Length = 253
Score = 130 bits (315), Expect = 3e-29
Identities = 77/226 (34%), Positives = 123/226 (54%), Gaps = 8/226 (3%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++ L RN+E L+ K+ ST ++T DL ES +++ + +D YGK+D+LVNN
Sbjct: 29 GAKVILIARNLEGLENTRKEIGNEDSTAAMTCDLVDESQTLQVVNQIMDTYGKIDILVNN 88
Query: 89 AGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 146
AG I ++ +L+N N+ ++ +T + + + K G R+
Sbjct: 89 AGAINDPIHFHEMQNSEIQKLINVNLLGVFNMTKAVLTKMADVKSGSIVNIGSISSERAI 148
Query: 147 PGV--LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 204
P V Y+ +KA++ FT+ +A+E A + +R NCVNPG+I + L + Q L
Sbjct: 149 PRVHLAVYSATKAAIPMFTKSIAVEYARRNIRCNCVNPGII-NSGSIKPYLDDPQARKVL 207
Query: 205 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHA 250
E E L R G+P++VA +A+LASD AS +TG + VDGG+ A
Sbjct: 208 E---ERLPLARVGEPEDVANAVAYLASDEASWVTGTILNVDGGKTA 250
>UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=3; Cyanobacteria|Rep: NAD-dependent
epimerase/dehydratase precursor - Anabaena variabilis
(strain ATCC 29413 / PCC 7937)
Length = 251
Score = 129 bits (312), Expect = 6e-29
Identities = 72/225 (32%), Positives = 123/225 (54%), Gaps = 6/225 (2%)
Query: 26 SKLGAQLSLTGRNV-ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
+K A++ + GR + E + V + + +D+TKE+D++ ++ K + +G+LD+
Sbjct: 26 AKQQAKVVVVGRRIDEGEETVRLIQEAGGEAFFVQSDVTKEADVKAMVDKAVGVFGRLDI 85
Query: 85 LVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG 142
NNAG++ E ++ + A+YDR+MN NV+ ++ + +L + G G
Sbjct: 86 AFNNAGMVGENPSLIEQTEAEYDRIMNVNVKGVWLSMKYEIAQMLKQGSGAIVNTSSGAG 145
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+ + PGV Y SK +V T+ AL+ A G+R+N V PG I T++ +++ A
Sbjct: 146 VVALPGVPLYTASKHAVVGLTKAAALQYAKAGIRINAVAPGSIETDMFEAATGGQDEVKA 205
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
++ H +GR G P EVA + FL+SD+AS ITG + VDGG
Sbjct: 206 YI---TGLHPIGRIGTPLEVANAVLFLSSDIASFITGEMLMVDGG 247
>UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;
n=4; Caenorhabditis|Rep: Dehydrogenases, short chain
protein 15 - Caenorhabditis elegans
Length = 278
Score = 129 bits (312), Expect = 6e-29
Identities = 82/258 (31%), Positives = 131/258 (50%), Gaps = 13/258 (5%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS----I 58
F+ KV L++ GA++++TGR+ E +Q+ + K + +
Sbjct: 4 FSDKVAIITGSSSGIGRSTAVLLAQEGAKVTVTGRSSEKIQETVNEIHKNGGSSDNINIV 63
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTI-ENTSLAQYDRLMNTNVR 114
DL + +++IK T+ +GK+D+L+NNAG +G I ++ +D +M N+R
Sbjct: 64 LGDLNESECQDELIKSTLSRFGKIDILINNAGAAFADPSGKIGSEAAIGIFDDMMKLNLR 123
Query: 115 SIYYLTMLAVPHLLESKGXXXXXXX-XXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 173
S+ L PHL+ SKG G + + Y I KA +DQ TR +ALEL P
Sbjct: 124 SVVELVKKCRPHLIASKGEIVNVSSIAAGPQPYIYYTYYGICKAGLDQLTRSLALELIPF 183
Query: 174 GVRVNCVNPGVILTELQRRGGLSEE---QYAAFLERTKETHALGRPGKPDEVAATIAFLA 230
VRVN V+PG+I T G+ ++ + + ++ GR GKP+E+A+ IAFLA
Sbjct: 184 DVRVNSVSPGLISTNFLGAVGMGDDVVKKTEEYYSTHRDCIPAGRTGKPEEIASLIAFLA 243
Query: 231 SDLAS-NITGASVPVDGG 247
+S I G S+ +DGG
Sbjct: 244 DRKSSAYIIGQSIVIDGG 261
>UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2;
Bacteroidetes|Rep: Short chain dehydrogenase -
Algoriphagus sp. PR1
Length = 252
Score = 128 bits (310), Expect = 1e-28
Identities = 74/249 (29%), Positives = 126/249 (50%), Gaps = 3/249 (1%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 59
M GK S+ GA L L+GRN EN ++ + ++ + +
Sbjct: 1 MRLKGKTAIITGATSGMGKAIAKRFSEEGAFLILSGRNQENGIELERSLNEAGGKAVFVK 60
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+ E ++K I ++GKLD++V NAG + G++ SLA++ MNTN ++++L
Sbjct: 61 GDVGIIETNEALVKAAISNFGKLDIVVTNAGKLGLGSVTEISLAEWQETMNTNFNAVFFL 120
Query: 120 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
+ A+P +++S G +SFP AY SKA++ + +A++ P +RVN
Sbjct: 121 SRFAIPEMIKSGGGTILANSSIAAFKSFPNHAAYCASKAALVALVKEMAVDYGP-NIRVN 179
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
+ PG + T L + + ++ T + + R GKP+++A+ FL SD AS IT
Sbjct: 180 TMCPGPVDTPLIWDSAKAFDNPDTIVQETAKNTLMNRLGKPEDIASLALFLVSDEASWIT 239
Query: 239 GASVPVDGG 247
G + P+DGG
Sbjct: 240 GVAYPIDGG 248
>UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein]
reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative
3-oxoacyl-[acyl-carrier protein] reductase -
Arthrobacter aurescens (strain TC1)
Length = 261
Score = 128 bits (310), Expect = 1e-28
Identities = 76/193 (39%), Positives = 105/193 (54%), Gaps = 4/193 (2%)
Query: 55 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 114
TL + AD+ IE II ++++ G LDVLVNNAGI TG TS + +M NV
Sbjct: 60 TLKV-ADVGDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVD 118
Query: 115 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 174
++Y T A+PHL++S+G GI + AY+ SK +V FTR VA++ A +G
Sbjct: 119 GLFYATRAALPHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVAVDYAQRG 178
Query: 175 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
VR N V PG +LT L ++ + + A E + LGR P+E+A FLAS A
Sbjct: 179 VRCNAVAPGPVLTPLLQK---NLDSTAGLKEAFGRSIPLGRIAAPEEIAPAFTFLASSDA 235
Query: 235 SNITGASVPVDGG 247
S I G + DGG
Sbjct: 236 SYINGHILAADGG 248
>UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1;
Zymomonas mobilis|Rep: Putative uncharacterized protein
- Zymomonas mobilis
Length = 254
Score = 128 bits (308), Expect = 2e-28
Identities = 78/255 (30%), Positives = 134/255 (52%), Gaps = 12/255 (4%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITA 60
+++GKV +K A +++ GR+ N+Q+ + + ++I A
Sbjct: 6 DYSGKVALVTGAGTGIGRETALAFAKAKAYVAIIGRSENNIQETLRLVTEMGGQAIAIQA 65
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLA--QYDRLMNTNVRSIYY 118
D+++E I+ I+KT++ +GKLD NNAGI E I + ++DR+++TN+ +++
Sbjct: 66 DVSQEDSIKAAIEKTVETFGKLDFAFNNAGI-EHKAIPAADIPSEEWDRIISTNLNGVFF 124
Query: 119 LTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
+P +L+S G G++ FPG AY SK + ++ AL+ A + +R+
Sbjct: 125 SMKHEIPAMLKSGSGSIVNTASGAGVKGFPGNGAYCASKFGLIGLSKAAALDYAKQHLRI 184
Query: 178 NCVNPGVILTELQRR--GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
N V PG+I T + +R GG E + A + +GR G P E+A T+ +L SDLA+
Sbjct: 185 NVVAPGIIETPMMQRFTGGTEEGRETAIAQ-----EPVGRAGHPKEIAGTVLWLCSDLAA 239
Query: 236 NITGASVPVDGGRHA 250
TG+ VDGG+ A
Sbjct: 240 FTTGSVFVVDGGQTA 254
>UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2;
Frankia|Rep: Putative dehydrogenase/reductase - Frankia
alni (strain ACN14a)
Length = 295
Score = 127 bits (307), Expect = 2e-28
Identities = 75/221 (33%), Positives = 115/221 (52%), Gaps = 7/221 (3%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++++ GR+ + V + + I AD+T ++ +I+ T+DH+G LD+L
Sbjct: 75 GARVAVVGRDKAKMDAVVESLAPLGEIIGIQADVTVVAEAARIVSATVDHFGGLDILATV 134
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSF 146
AG+ E + + + A YD + NV+ Y+ A HL++ +G G+R+F
Sbjct: 135 AGVFEGAPLLDATEADYDIQFDLNVKGTYFCAQAAARHLVDQGRRGKIITVGSVAGLRAF 194
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 206
PGV Y +KA+V T+ +A ELAP G+ VNCV PG I ++ LS A E
Sbjct: 195 PGVSVYGATKAAVGFLTQVLAGELAPHGINVNCVVPGSI--DMPTNKLLSPPGAA---EA 249
Query: 207 TKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ R G P +VAA +LASD A + G S+ VDGG
Sbjct: 250 SAAGTPARRNGLPVDVAAAAVYLASDSADFVHGTSLVVDGG 290
>UniRef50_A3H8L6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain
dehydrogenase/reductase SDR - Caldivirga maquilingensis
IC-167
Length = 283
Score = 127 bits (307), Expect = 2e-28
Identities = 80/249 (32%), Positives = 128/249 (51%), Gaps = 9/249 (3%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS---TLSITAD 61
GKVV ++G+++ + R+ + +Q V K + + S + + D
Sbjct: 16 GKVVIVTGSTRGIGYEIVKLFKEMGSRVVVNARSADEVQTVVKKLNDYVSDGEAIGVAGD 75
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
++K D EKI+ +T+D YGK+DVLVNNAGI N S+ ++R + ++ S +Y++
Sbjct: 76 VSKYEDCEKIVNETVDKYGKIDVLVNNAGINMIRDSLNLSIDDWERTLRIDLFSAFYMSQ 135
Query: 122 LAVPHLL--ESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
L ++ + KG G I + P AY +KA + TR +A+E AP G+RVN
Sbjct: 136 LVARTMVAKKVKGSIVNIASMVGPIVALPKRAAYAAAKAGLVGLTRVLAVEWAPLGIRVN 195
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
+ PG I + Q ++ +Y + + +GR G EVA FLAS+LAS +T
Sbjct: 196 AIAPGYIWSSAQ-EVNIARGEYTR--QDIEGRVPMGRYGDAREVAYVAVFLASELASYVT 252
Query: 239 GASVPVDGG 247
GA + VDGG
Sbjct: 253 GALITVDGG 261
>UniRef50_Q28Q26 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Jannaschia sp. CCS1|Rep: Short-chain
dehydrogenase/reductase SDR - Jannaschia sp. (strain
CCS1)
Length = 254
Score = 127 bits (306), Expect = 3e-28
Identities = 82/222 (36%), Positives = 114/222 (51%), Gaps = 8/222 (3%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA++++TGR E L+ V+ + +I A D++ E D ++I + H G L L N
Sbjct: 30 GAKVTITGRRAEKLEDVA---GAIGPSCAIAAGDVSIEEDRRRMIDTAVAHGGGLQGLFN 86
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 147
NAG + G I + + +MN NV + LT LA PHL E G R+FP
Sbjct: 87 NAGNMLRGPITDLAAEDILEVMNVNVVAGMRLTGLAAPHLEEHGGAVVFVGSGHTRRAFP 146
Query: 148 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL--SEEQYAAFLE 205
G Y SK +V+ + +A EL PKG+RVNC+ PG + TE+ R G+ S E L
Sbjct: 147 GASPYAASKGAVEVLAQVLAAELGPKGIRVNCIVPGAVPTEINVRAGIAASFEDNKVRLN 206
Query: 206 RTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ H LGR G P E+A + L A TGAS+ VDGG
Sbjct: 207 SMVDDHPLGRIGTPQEIAEAVDHLLR--AEWTTGASLVVDGG 246
>UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Caulobacter sp. K31|Rep: Short-chain
dehydrogenase/reductase SDR - Caulobacter sp. K31
Length = 277
Score = 127 bits (306), Expect = 3e-28
Identities = 73/181 (40%), Positives = 103/181 (56%), Gaps = 5/181 (2%)
Query: 71 IIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LE 129
+I T+ +G+LD+LVNNAGI G + SL +D L+ NV S++Y A+PH+ +
Sbjct: 72 LIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRAAIPHMRRQ 131
Query: 130 SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G G+R AY+ SKA+V FTR +AL+ A + +RVN + PG + TE+
Sbjct: 132 GGGAIINVASIAGLRGETLAAAYSASKAAVVNFTRSLALDHADENIRVNAICPGSVETEM 191
Query: 190 QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRH 249
+S Y A + +T R G+PD+VAA AFLASD AS I G ++PVDGG
Sbjct: 192 NNL-MMSRPDYIA---QWIKTIPANRFGRPDDVAALAAFLASDDASFIVGQAIPVDGGTS 247
Query: 250 A 250
A
Sbjct: 248 A 248
>UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Shewanella sediminis HAW-EB3|Rep: Short-chain
dehydrogenase/reductase SDR - Shewanella sediminis
HAW-EB3
Length = 245
Score = 127 bits (306), Expect = 3e-28
Identities = 79/246 (32%), Positives = 117/246 (47%), Gaps = 6/246 (2%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITAD 61
NF KVV GA + +TGR L++ S++ I D
Sbjct: 3 NFENKVVLITGGGTGIGKATASAFIAKGATVVITGRRQSVLEETSQELGP--QVYPIVGD 60
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
++K+ +I+++TI +G+LDVLVNNAG + G + TS + + TNV ++ L
Sbjct: 61 VSKKGGPARIVEETISKFGRLDVLVNNAGTGKMGPLSETSDEDIESIYRTNVFALLALVR 120
Query: 122 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
A HL SKG P V AY SKA+V+ TR +A EL P G+RVN V
Sbjct: 121 EATVHLANSKGAVVNISSVAAQGMMPAVAAYASSKAAVEHATRLLAAELGPMGIRVNAVA 180
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG+ T++ +EE + +T +GR G+P ++A + ++ A ITG S
Sbjct: 181 PGLTNTDIAADVKSNEEMLGMIIAQT----PMGRLGEPKDIANVVLLMSGSGAGWITGQS 236
Query: 242 VPVDGG 247
V GG
Sbjct: 237 VQAGGG 242
>UniRef50_Q3IVH5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Rhodobacteraceae|Rep: Short-chain
dehydrogenase/reductase SDR - Rhodobacter sphaeroides
(strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158)
Length = 259
Score = 126 bits (305), Expect = 4e-28
Identities = 70/194 (36%), Positives = 104/194 (53%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 116
+I AD + + + +D G+LDVLVNNAG+++ +E +LA ++R + N+ +
Sbjct: 46 AIAADFADADAPARAVAEAVDRAGRLDVLVNNAGVMQEARVEEMALADWERTIRVNLTAP 105
Query: 117 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
+ A+PHL +G G+ + P AY SKA + TR VA++ +G+R
Sbjct: 106 FLAIRAALPHLRAVRGAIVNVGSIEGLGANPRHAAYCASKAGLHGLTRAVAVDHGAEGIR 165
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
N V PG I TEL + AF H +GR G+P+EVAA +A+LASD A+
Sbjct: 166 CNAVAPGWIETELNEAFVEAMPDPEAFRRGIGRIHPVGRTGQPEEVAALVAWLASDEAAF 225
Query: 237 ITGASVPVDGGRHA 250
+TG VDGGR A
Sbjct: 226 VTGQVWTVDGGRMA 239
>UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 402
Score = 126 bits (305), Expect = 4e-28
Identities = 84/258 (32%), Positives = 125/258 (48%), Gaps = 13/258 (5%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL----QKVSKDCDKFASTLSI 58
F+GKV ++ GA++++TGRN E L Q + K + L+I
Sbjct: 126 FSGKVALVTGSSNGIGRAAALLFAQQGAKVTITGRNAERLEETRQAILKSGVPAENVLAI 185
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQ----YDRLMNTNVR 114
ADL + +I T+ +G+LD+LVNNAG + Q +D+ N+R
Sbjct: 186 AADLATDQGQTDLINGTLQKFGRLDILVNNAGAAVNDPQGRMGIDQQIEDFDKTFQINMR 245
Query: 115 SIYYLTMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPK 173
S+ L A HL+++KG G + P ++ Y +SKA++DQFTR A+ L
Sbjct: 246 SVVTLVQKAKEHLIKTKGEIINVSSIGGGPHAQPDMMYYGMSKAALDQFTRSTAITLIQH 305
Query: 174 GVRVNCVNPGVILTELQRRGGL---SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 230
GVRVN V+PG + T G + E+ + E KE G +P E+A IAFLA
Sbjct: 306 GVRVNSVSPGGVYTGFGEAMGFPPGALEKIMKYFESHKECVPCGHMAQPIEIAQVIAFLA 365
Query: 231 S-DLASNITGASVPVDGG 247
++S I G S+ DGG
Sbjct: 366 DRTMSSYIIGQSIIADGG 383
Score = 72.5 bits (170), Expect = 9e-12
Identities = 43/103 (41%), Positives = 59/103 (57%), Gaps = 4/103 (3%)
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL---SEEQYAAFLE 205
++ Y +SKA++DQFTR A+ L GVRVN V+PGV+ T + G + E+ F E
Sbjct: 1 MMYYGMSKAALDQFTRSTAITLIQHGVRVNSVSPGVVYTGIGEAMGFPPGAFEKTMKFYE 60
Query: 206 RTKETHALGRPGKPDEVAATIAFLAS-DLASNITGASVPVDGG 247
KE G +P E+A IAFLA ++S I G S+ DGG
Sbjct: 61 SHKECVPCGHMAQPVEIAQVIAFLADRTMSSYIIGQSIIADGG 103
>UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 271
Score = 126 bits (304), Expect = 5e-28
Identities = 65/187 (34%), Positives = 101/187 (54%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D++K D+E+ + I + ++D+LV+NAGI G + T +DR++ N++ + ++
Sbjct: 64 DVSKSKDVEQAVGDVITKHSQIDILVSNAGIQYYGDVITTPEDDWDRVIGVNLKGCFLIS 123
Query: 121 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
VPH++ + G + AY SK +V R +AL+ A KG+RVNCV
Sbjct: 124 KFCVPHMISNGGAIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMALDYAHKGIRVNCV 183
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PG I T + + + HALGR GKPDEVA + +LAS ++S ITGA
Sbjct: 184 CPGTIDTPMLHWAASLSPDPESVIRTCDRMHALGRIGKPDEVADAVLYLASPMSSFITGA 243
Query: 241 SVPVDGG 247
++ VDGG
Sbjct: 244 ALLVDGG 250
>UniRef50_Q0RF25 Cluster: Putative oxidoreductase; short-chain
dehydrogenase/reductase; n=1; Frankia alni ACN14a|Rep:
Putative oxidoreductase; short-chain
dehydrogenase/reductase - Frankia alni (strain ACN14a)
Length = 297
Score = 125 bits (302), Expect = 9e-28
Identities = 84/249 (33%), Positives = 126/249 (50%), Gaps = 9/249 (3%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITAD 61
FAG VV + GA + + R ++ ++ ++ S + D
Sbjct: 36 FAGTVVLVTGAGRGLGRTIAEAFAVEGATVVVAARTARYGERTVREFRERGLSASLVIGD 95
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
L + +D+ + + + +G LDV+V++A G + D L+ +NV +++++T
Sbjct: 96 LAERADVATMFDEAVARHGALDVVVHSAADNAQGLLAEIDDDTLDYLLRSNVHALHWITR 155
Query: 122 LAVPHLLESK--GXXXXXXXXXGIRSF-PGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
AVPHL SK G R F PG+ AY +KA ++ F R +A EL P GVRVN
Sbjct: 156 AAVPHLTRSKLPGRMIFISSGAANRVFSPGLNAYGSTKAYLESFARGLAGELGPLGVRVN 215
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
V PG+ +TE + G L+ Q A T+ LGR G P+E+AA + FLAS AS IT
Sbjct: 216 VVGPGLTVTE-RMLGHLTHAQADALAS----TYPLGRAGLPEEIAAAVLFLASREASYIT 270
Query: 239 GASVPVDGG 247
GAS+ VDGG
Sbjct: 271 GASLLVDGG 279
>UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcohol
dehydrogenase TsaC; n=5; Proteobacteria|Rep:
Toluenesulfonate zinc-independent alcohol dehydrogenase
TsaC - Comamonas testosteroni (Pseudomonas testosteroni)
Length = 252
Score = 125 bits (302), Expect = 9e-28
Identities = 76/228 (33%), Positives = 120/228 (52%), Gaps = 4/228 (1%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 83
LS+ GA + + N E Q+++ + + L + D++KE+D ++ I G L
Sbjct: 25 LSQAGAAVLVADLNAEGAQRMATELNAAGGRALGMACDVSKEADYRAVVDAAIAQLGGLH 84
Query: 84 VLVNNAGIIETGTIE-NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 141
++VNNAG + ++DR+ N++S+Y+ A+PH + G
Sbjct: 85 IVVNNAGTTHRNKPALAVTEDEFDRVYRVNLKSVYWSAQCALPHFAQQGHGVMVNVASTT 144
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G+R PG+ Y+ SKA++ T+ +ALE A GVR+N VNP + T + + E
Sbjct: 145 GVRPGPGLTWYSGSKAAMINLTKGLALEFARSGVRINAVNPMIGETPMMA-DFMGMEDTP 203
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRH 249
A ER LGR +PD+VA+ +AFLASD AS +TG + VDGGR+
Sbjct: 204 ANRERFLSRIPLGRFTRPDDVASAVAFLASDDASFLTGVCLDVDGGRN 251
>UniRef50_A1UII7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=24; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Mycobacterium sp. (strain KMS)
Length = 251
Score = 125 bits (302), Expect = 9e-28
Identities = 77/221 (34%), Positives = 112/221 (50%), Gaps = 9/221 (4%)
Query: 29 GAQLSLT-GRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLV 86
GA ++ T G +V + KV D + L I AD + I + +T+ G LD+LV
Sbjct: 35 GAAVAFTYGSSVSDADKVVVDVSRGGGRVLPIRADSSDAGQIASAVDETVTRLGGLDILV 94
Query: 87 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 146
NNAG+ G +E+ L Q+DRL+ NVR ++ AVPHL +
Sbjct: 95 NNAGVAHLGAVESFPLDQFDRLVAVNVRGVFVAIQCAVPHLGDGGRIINIGSVNADRVPS 154
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 206
PG+ Y ++KA+V TR +A EL P+G+ VN V PG I T++ G F +
Sbjct: 155 PGLSVYAMTKAAVAGLTRGLARELGPRGITVNTVAPGPIATDMNPAEG-------EFADA 207
Query: 207 TKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+E A+G G P +VA ++LA A +TGA+ VDGG
Sbjct: 208 AREIIAVGHYGNPTDVAGVASYLAGPDAGYVTGANWTVDGG 248
>UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=2; Geobacillus|Rep: 3-oxoacyl-[acyl-carrier
protein] reductase - Geobacillus kaustophilus
Length = 256
Score = 124 bits (300), Expect = 2e-27
Identities = 86/257 (33%), Positives = 124/257 (48%), Gaps = 15/257 (5%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS---TLS 57
M FA V L++ GA + L GR L++ +D +
Sbjct: 1 MRFANTVAVITGGGSGIGRATAVRLAQEGATVVLVGRTAVKLEETVQDITRLGVPGVADR 60
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSI 116
AD+T + + + YG L VLVNNAGI T +E T ++D + N++S+
Sbjct: 61 FAADVTDHEQVRALAAYVQNRYGDLHVLVNNAGISTHTKWLELTE-QEWDDVQRVNMKSV 119
Query: 117 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLA------YNISKASVDQFTRCVALEL 170
+ ++ P ++E + S G A Y+ +KA V T+ +ALEL
Sbjct: 120 FLVSQTLAPLMIEGAKRERANRAIVNVASLSGHQAGAEIPHYSAAKAGVINLTKSLALEL 179
Query: 171 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 230
AP G+RVN V+PG + T L RG L E++ +ER ALGR G P+E+A IAFLA
Sbjct: 180 APYGIRVNSVSPGFVETPLTERG-LQNERFVKAIERNT---ALGRVGAPEEIANVIAFLA 235
Query: 231 SDLASNITGASVPVDGG 247
S AS +TG+ V VDGG
Sbjct: 236 SSEASYMTGSDVLVDGG 252
>UniRef50_A1DKR3 Cluster: Short chain dehydrogenase/reductase family
oxidoreductase, putative; n=1; Neosartorya fischeri NRRL
181|Rep: Short chain dehydrogenase/reductase family
oxidoreductase, putative - Neosartorya fischeri (strain
ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 255
Score = 124 bits (300), Expect = 2e-27
Identities = 84/257 (32%), Positives = 124/257 (48%), Gaps = 14/257 (5%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQ-LSLTGRNVENLQKVSKDCDKFASTLSIT- 59
+ AG+V L+KLGA L+L+ NVE LQK +C ++ S +++T
Sbjct: 4 SIAGRVYTVTGASSGIGQATAVKLAKLGAAGLALSDVNVEGLQKTKDECSRYESNVTVTR 63
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE---TGTIENTSLAQYDRLMNTNVRSI 116
D+++ + + +T+ +G+LD N AGI T E S +DRLM+ N++ +
Sbjct: 64 VDVSRNDQVTRWASETVQQFGRLDGAANIAGIAMGDGTTNCETISPESWDRLMDVNLKGV 123
Query: 117 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
+PHL G G+R P AY+ SK V + A E P G+R
Sbjct: 124 MLCMRAQLPHLPRPGGVIVNVSSTSGLRGLPHNAAYSSSKFGVIGLSASAAGEFGPLGIR 183
Query: 177 VNCVNPGVILTELQRRG---GLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 233
+N + PG + T + R G GL + Q +K T LGR G+ E+A + FL SD
Sbjct: 184 INSLLPGPVDTAIFRDGEARGLFDSQIL-----SKAT-CLGRMGQAHEIANVLCFLLSDD 237
Query: 234 ASNITGASVPVDGGRHA 250
AS +TGA VDGG A
Sbjct: 238 ASYVTGAHWTVDGGYSA 254
>UniRef50_Q01TL3 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Bacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Solibacter
usitatus (strain Ellin6076)
Length = 249
Score = 124 bits (299), Expect = 2e-27
Identities = 74/246 (30%), Positives = 120/246 (48%), Gaps = 5/246 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
F GK + GA++ +TGRN ++ + A + + +D
Sbjct: 4 FKGKTALITGGTTGLGLATAKLFIEEGARVIVTGRNPATIKAAQAELGDNA--IVVPSDA 61
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
T D++ + K + +GK+DVL NAG E + A YD ++N N + Y++
Sbjct: 62 TSLPDMDALATKVKETFGKIDVLFVNAGYGHFVPFEAVTEAVYDEMLNLNAKGPYFIVQK 121
Query: 123 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
P L+ +++ P + AY +KA++ TR +A EL P+G+RVN V P
Sbjct: 122 LAP-LMPEGSSVVFTTSIANVKAVPTLSAYGAAKAALRAMTRSIAAELLPRGIRVNAVTP 180
Query: 183 GVI-LTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
G I T++ R G+ +E + E+ + R G+P+E+A +AFLA D A+ TGA
Sbjct: 181 GPIGATDVMHRLGMPKEAQDQVYLQMAESVPMKRLGRPEEIAKAVAFLAID-ATFTTGAE 239
Query: 242 VPVDGG 247
+PVDGG
Sbjct: 240 LPVDGG 245
>UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=3; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Shewanella
pealeana ATCC 700345
Length = 262
Score = 124 bits (298), Expect = 3e-27
Identities = 80/248 (32%), Positives = 120/248 (48%), Gaps = 5/248 (2%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLT 63
GKV L+ GA++ + GRN L V + + + AD++
Sbjct: 13 GKVAFITGAGSGIGAATAVRLAAEGAKVMICGRNQPPLDLVVAQIKQAGGVATAVIADVS 72
Query: 64 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLA 123
E+++ I++ YG LD++VNNA G+IE + T+V ++ T A
Sbjct: 73 NETELVAAIERCASEYGSLDIMVNNAMAFTWGSIEEMDTQAWHENFKTSVDGTFWGTKAA 132
Query: 124 VPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 183
+ + + G G P + Y+ +KA+V F+R A E A +RVN V P
Sbjct: 133 MKLMKSNGGSIINLSSICGELGTPWMSGYSAAKAAVTNFSRAAAAEGAASNIRVNTVIPA 192
Query: 184 VILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVP 243
V+ T G LS A + T+ +GR G+PDE+A+ IAFLASD AS +TG S+P
Sbjct: 193 VVETP-ATEGMLSN---ATARKNTERLIPMGRVGQPDELASVIAFLASDEASYVTGVSLP 248
Query: 244 VDGGRHAM 251
VDGGR A+
Sbjct: 249 VDGGRAAV 256
>UniRef50_Q23618 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 124 bits (298), Expect = 3e-27
Identities = 86/267 (32%), Positives = 135/267 (50%), Gaps = 19/267 (7%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST----LSI 58
F+GKVV + GA++ L GR+ ++++K K C + + L
Sbjct: 6 FSGKVVLISGSSKGIGQATAVKFAAEGAKIVLNGRSADDVEKTRKLCMEVGAKPWDLLPT 65
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE---TGTIE-NTSLAQYDRLMNTNVR 114
D+T E ++ ++ I ++GKLD+L+NNAG +E TG + DR N+N +
Sbjct: 66 VGDITNEDFVKMMVNTVIHNFGKLDILINNAGTLEVDMTGKEGWEMGVDVMDRSWNSNFK 125
Query: 115 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP-GVLA---YNISKASVDQFTRCVALEL 170
S+ LT A+PHL+++KG + S P GV++ Y + KA++DQ +R +A E
Sbjct: 126 SVLMLTQAAMPHLIKTKGDIVNVSTF--LSSGPIGVMSMPYYAVPKAALDQMSRSMAHEY 183
Query: 171 APKGVRVNCVNPGVILTELQRR----GGLSEEQYAAFLERTKETHALGRPGKPDEVAATI 226
KGVR+N VNPG++ T R G + + +++ E LGR + +VA TI
Sbjct: 184 MLKGVRLNTVNPGLVSTSFFARLPGVGDDNARKMENYVQSKTEYIPLGRVCQASDVAETI 243
Query: 227 AFLASDLASN-ITGASVPVDGGRHAMC 252
FLA S I G S+ +DGG C
Sbjct: 244 LFLADRKVSECIVGQSIIIDGGSRLCC 270
>UniRef50_Q930L7 Cluster: Putative; n=1; Sinorhizobium meliloti|Rep:
Putative - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 253
Score = 123 bits (296), Expect = 5e-27
Identities = 76/246 (30%), Positives = 125/246 (50%), Gaps = 8/246 (3%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
F GKV L + GA + ++GR + L V+ S + + A++
Sbjct: 5 FDGKVAIVTGGGSGIGAAIANRLLEEGASVMMSGRTEKRLSDVASKMPADRSGIFV-ANV 63
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ D + ++ T++ +G++D +VN AG+ GTI+ TS +D + +++ ++Y++
Sbjct: 64 SSRPDCDALVAATVERFGRIDTVVNAAGMNFVGTIQETSDQDWDECIASDLSGVFYMSRA 123
Query: 123 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
AVPHL E+KG + AYN +K V TR A +L GVR N V P
Sbjct: 124 AVPHLKETKGSIVNIGSVSSLGGGWSHAAYNAAKGGVANLTRSAACDLGKFGVRANTVAP 183
Query: 183 GVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASV 242
G+ +T + + ++ A LE+ + L R G+P A+ +AFLASD A+ ITG +
Sbjct: 184 GLTVTGMVE--AIMDDD--ALLEKAWDRIPLRRAGQP---ASAVAFLASDEAAWITGIVL 236
Query: 243 PVDGGR 248
PVDGG+
Sbjct: 237 PVDGGQ 242
>UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
dehydrogenase/reductase SDR - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 251
Score = 123 bits (296), Expect = 5e-27
Identities = 78/251 (31%), Positives = 126/251 (50%), Gaps = 8/251 (3%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 59
M GKV L++ GA++ + NVE +K +D K L +
Sbjct: 1 MRLEGKVCVVTGGATGIGEASALALAREGARVVVGDVNVEEGRKTVEDIKKEGGEALFVE 60
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYY 118
D+++E +++++T+ +G++DVL NNAGI I G++ + + R NV I++
Sbjct: 61 CDVSREEGARRLVEETVGAFGRIDVLFNNAGINITEGSVPEMKVEDWRRTFAVNVDGIFW 120
Query: 119 LTMLAVPHLLESKGXXXXXXXX-XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
+ A+P + ++ G + G AY SK +V TR +A++ A + +RV
Sbjct: 121 CSRYAIPEMRKNGGGRIINTASPSSFVGWAGNAAYIASKGAVMSLTRAMAMDHAKENIRV 180
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKET-HALGRPGKPDEVAATIAFLASDLASN 236
N + PG+IL+ L GL+ Q E KE+ H +GRPG P++VA + FLA D A
Sbjct: 181 NAIVPGLILSPL----GLNWVQQQEDPEAVKESIHPIGRPGYPEDVAPVVVFLAQDDAEF 236
Query: 237 ITGASVPVDGG 247
TGA +DGG
Sbjct: 237 ATGAPFFMDGG 247
>UniRef50_Q126U8 Cluster: Short-chain dehydrogenase/reductase SDR;
n=14; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 274
Score = 123 bits (296), Expect = 5e-27
Identities = 71/205 (34%), Positives = 110/205 (53%), Gaps = 16/205 (7%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L + D+ ++ ++ ++ +TI +G++DVLVNNAGI + A +D ++ N++
Sbjct: 65 LYVHCDVGDKAQVDALVAQTIAAHGRIDVLVNNAGIFRAADFLEITEADFDAVLRINLKG 124
Query: 116 IYYLTMLAVPHLLE-----------SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTR 164
+ + + S+G + + P + +YN+SK ++Q TR
Sbjct: 125 SFLVGQAVAREMARAEARPGIGGSASRGSIVNMSSVNSVLTIPTIASYNVSKGGINQLTR 184
Query: 165 CVALELAPKGVRVNCVNPGVILTELQRRGGL-SEEQYAAFLERTKETHALGRPGKPDEVA 223
+AL LA KG+RVN V PG I T+L + L SEE A + RT + R G+P E+A
Sbjct: 185 VMALALADKGIRVNAVAPGTIATDLAAKAVLTSEEAKARIMSRT----PMKRLGEPSEIA 240
Query: 224 ATIAFLASDLASNITGASVPVDGGR 248
T+A+LASD AS ITG V VDGGR
Sbjct: 241 DTVAYLASDAASYITGEIVMVDGGR 265
>UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase
bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis
oxidoreductase bacC - Bacillus subtilis
Length = 253
Score = 123 bits (296), Expect = 5e-27
Identities = 68/195 (34%), Positives = 111/195 (56%), Gaps = 7/195 (3%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
+ D+T E+ + ++ + +G LDVL+NNAGI I L+ +++++ N+ ++
Sbjct: 57 VQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMF 116
Query: 118 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
++ A+ H+L + KG G+ ++P + AYN SK V Q T+ +A++ A +R
Sbjct: 117 LMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIR 176
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA----LGRPGKPDEVAATIAFLASD 232
VNCV PG+I T L + L E LE K+ A L R GKP+E+A + FLASD
Sbjct: 177 VNCVCPGIIDTPLNEKSFL--ENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASD 234
Query: 233 LASNITGASVPVDGG 247
L+S +TG+++ DGG
Sbjct: 235 LSSYMTGSAITADGG 249
>UniRef50_A0FWP6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia phymatum
STM815
Length = 257
Score = 122 bits (295), Expect = 7e-27
Identities = 77/247 (31%), Positives = 115/247 (46%), Gaps = 3/247 (1%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
M+FA K L GA++++TGR+ + L + + + S L I A
Sbjct: 1 MSFANKTALITGGNGGIGFAAARLLIAQGARVAITGRDQKKLDEAAAELGP--SALPIRA 58
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+ + I+ ++K D +GKLD++ NAG+ + T+ +++ +M TNV S++
Sbjct: 59 DINDPAAIDAVMKTIADTFGKLDIVFANAGVSGATPVGETTAEKFEAIMRTNVTSVFLTV 118
Query: 121 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
AVP L+ G PG AY+ SKA++ R +A EL +G+RVN V
Sbjct: 119 QAAVP-LMGEGGAIVLNGSVMRQLGAPGSSAYSASKAAISGMARVLASELVTRGIRVNTV 177
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PG T + RG A + R DEVA FLASD AS +T A
Sbjct: 178 IPGGTRTSIWTRGDREGATLDATEAALSPMIPMNRFALADEVAQAAVFLASDAASGMTAA 237
Query: 241 SVPVDGG 247
+ VDGG
Sbjct: 238 EIVVDGG 244
>UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Pedobacter sp. BAL39|Rep: Short-chain
dehydrogenase/reductase SDR - Pedobacter sp. BAL39
Length = 250
Score = 122 bits (294), Expect = 9e-27
Identities = 69/220 (31%), Positives = 118/220 (53%), Gaps = 6/220 (2%)
Query: 29 GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA ++ GRN E L++ + D F ++I D+T D+E++++ T + +GK+D+LV
Sbjct: 30 GASGAIVGRNQETLKRAASQLGDGF---IAINGDVTNPGDLERMMRNTSEQFGKIDILVA 86
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 147
NAG TGT+ + S + YD+ M+ N++S+Y+ A+P++ + R++P
Sbjct: 87 NAGAGTTGTVADISESDYDKTMDLNLKSVYFTVQKALPYMADGSSIILIGSNAAH-RAYP 145
Query: 148 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 207
Y +KA+V + + +L + +RVN + PG T + + EQ A
Sbjct: 146 SFGLYGAAKAAVIFLAKSFSNDLLDRKIRVNVITPGTTDTPAFDK-FVPAEQIEALKTHF 204
Query: 208 KETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
T +GR G+P ++ T FLASD +S + GA + VDGG
Sbjct: 205 AGTMPIGRIGQPSDIGKTAVFLASDDSSFLLGAELLVDGG 244
>UniRef50_A1ZKI7 Cluster: 3-oxoacyl-acyl-carrier-protein reductase;
n=1; Microscilla marina ATCC 23134|Rep:
3-oxoacyl-acyl-carrier-protein reductase - Microscilla
marina ATCC 23134
Length = 253
Score = 122 bits (294), Expect = 9e-27
Identities = 74/226 (32%), Positives = 118/226 (52%), Gaps = 4/226 (1%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFAST--LSITADLTKESDIEKIIKKTIDHYGK 81
FL++ GA++ +TGR+ E L+ +++ K + L+I AD + +K+ + D +GK
Sbjct: 26 FLAE-GAKVVVTGRSDEKLKATNEELAKIHANHFLTIKADAADVTSNKKVFEAAQDKFGK 84
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 141
+D+L NAG+ + + + A YD +MNTN++ ++L +P+ E
Sbjct: 85 VDILFANAGVGRFMPLSDVTEAMYDEVMNTNLKGPFFLVQAGLPYFNEGASIILNTSVSN 144
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
+ PG AY SKA + R A EL+ +RVN ++PG I T + + GL EE
Sbjct: 145 QM-GMPGASAYAASKAGLRLLARVFAAELSAHKIRVNAISPGPIDTPIWGKTGLPEEAVQ 203
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
ALGR G +E+A ++ FLAS AS +TG + VDGG
Sbjct: 204 EMGAGIASQVALGRFGTSEEIAKSVLFLASQDASFVTGIELEVDGG 249
>UniRef50_Q5NZC3 Cluster: Predicted short chain dehydrogenase; n=4;
Bacteria|Rep: Predicted short chain dehydrogenase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 250
Score = 122 bits (293), Expect = 1e-26
Identities = 67/219 (30%), Positives = 113/219 (51%), Gaps = 3/219 (1%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA+++ GRN E L ++ +++ D T D+++++ +T+ +G +D++V N
Sbjct: 31 GAKVAAFGRNTEALDALA--AAHAGKVVTVKGDATCAEDLQRLVDETLKAFGGVDIVVPN 88
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 148
AGI + E+++ ++ + N+ + L +PH+ + FPG
Sbjct: 89 AGIARVVSFEDSTREAFETQFSVNLFAAAETVRLFLPHIRRGGSVQFITTFLTQV-GFPG 147
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 208
+ Y+ SKA++ F + +A ELAP+G+RVN + PG I T L GL + A +
Sbjct: 148 LAIYSASKAALKSFAQTLAAELAPRGIRVNSIAPGPIATPLWGTVGLPPDVLGAVAGQIN 207
Query: 209 ETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
G GKP+++A T FLASD A NI G + VDGG
Sbjct: 208 SRLMTGEFGKPEDIAETSVFLASDGAKNIYGQDIVVDGG 246
>UniRef50_A3IE79 Cluster: 3-ketoacyl-(Acyl-carrier-protein)
reductase; n=2; Bacillaceae|Rep:
3-ketoacyl-(Acyl-carrier-protein) reductase - Bacillus
sp. B14905
Length = 248
Score = 122 bits (293), Expect = 1e-26
Identities = 68/195 (34%), Positives = 113/195 (57%), Gaps = 11/195 (5%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYL 119
++ +E + I ++ +D YG++D LVN GI + T IE ++ +++RLM+ NV+S++
Sbjct: 56 NVLQEERVNDIFQQIVDKYGRIDGLVNALGIAQAATPIEQVTMDEWNRLMDVNVKSLFIT 115
Query: 120 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
VP + + KG +R PG+ AY SK + + FTR +A+ELAP +RVN
Sbjct: 116 AKAVVPFMKKQQKGSIVTIASISAVRPRPGLQAYIASKGAAESFTRGLAIELAPNQIRVN 175
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTK-----ETHALGRPGKPDEVAATIAFLASDL 233
++PG + Q G + + A +E+TK ++ LGR KP ++A +++L SD
Sbjct: 176 TIHPGP--ADTQMLGQFAAQ--GADVEQTKQSVFVQSVPLGRLVKPSDIAGAVSYLLSDA 231
Query: 234 ASNITGASVPVDGGR 248
AS +TG ++ VDGGR
Sbjct: 232 ASMVTGTTLHVDGGR 246
>UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Bacillus coagulans 36D1|Rep: Short-chain
dehydrogenase/reductase SDR - Bacillus coagulans 36D1
Length = 262
Score = 122 bits (293), Expect = 1e-26
Identities = 70/198 (35%), Positives = 112/198 (56%), Gaps = 9/198 (4%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSI 116
+ D++K D++ ++ +D YGK+D+L+NNAG + + + +D+LM NVR +
Sbjct: 62 VRTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGV 121
Query: 117 YYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 175
+ +PH++ K G G+ P ++AY SK +V T+ +E AP GV
Sbjct: 122 FLGMKYVLPHMISQKSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAGIEAAPSGV 181
Query: 176 RVNCVNPGVILTELQRR--GGLSEEQYAAFLERTKETHA----LGRPGKPDEVAATIAFL 229
RVN V PGV+ TE+ R+ G + AA E+T++ A GR +P+EVA + +L
Sbjct: 182 RVNAVCPGVVDTEMMRKIENGFAGGDSAA-AEQTRQQMAASAPTGRYTQPEEVANVLLYL 240
Query: 230 ASDLASNITGASVPVDGG 247
ASDL+S+I G +V +DGG
Sbjct: 241 ASDLSSHIIGQTVVIDGG 258
>UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;
n=2; Thermotoga|Rep: Uncharacterized oxidoreductase
TM_0325 - Thermotoga maritima
Length = 251
Score = 121 bits (291), Expect = 2e-26
Identities = 76/253 (30%), Positives = 124/253 (49%), Gaps = 4/253 (1%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-IT 59
MNF GKVV ++ GA++++ + E ++ + + I
Sbjct: 1 MNFQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIF 60
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+ K D E+I+KKT++ +G+LD+LVNNAGI+ G IE TS +D+ M NV+ + L
Sbjct: 61 GDVAK--DAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118
Query: 120 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
+ AV + + G G+ P Y++SKA++ TR +A++ G+RVN
Sbjct: 119 SKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRVN 178
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
V PG +E + L++ + R GK +E+A I F A D A +T
Sbjct: 179 AVCPGTTQSEGLMARVKASPNPEELLKKMTSRIPMKRLGKEEEIAFAILFAACDEAGFMT 238
Query: 239 GASVPVDGGRHAM 251
G+ + +DGG A+
Sbjct: 239 GSIINIDGGSTAV 251
>UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 258
Score = 120 bits (290), Expect = 3e-26
Identities = 69/224 (30%), Positives = 119/224 (53%), Gaps = 11/224 (4%)
Query: 29 GAQ-LSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 86
GA+ L + GR ++ + C + A+ +++ D+T+E D+ +++ ++ G+LDV
Sbjct: 37 GAEALIIAGRREAEIEATAAACREIGAAAIALKTDITREDDVARLVGIAVERCGRLDVAF 96
Query: 87 NNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIR 144
NNAG E +E YD + +TNVR+++ +P +L + +G G+R
Sbjct: 97 NNAGFQERRAPLEEQGTEIYDSVFDTNVRALFLCLRHQLPAMLAQGRGSIVVNASVSGVR 156
Query: 145 S-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 203
+ PG Y+ SKA+ TR A+E AP+G+R+N + PG ++T++ R G+ + A
Sbjct: 157 NPNPGFSLYSASKAAAISLTRSAAMENAPRGIRINAIAPGRVVTDMMLRAGVGDVATVA- 215
Query: 204 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
L R G P+EVA + +L+SD AS + G + DGG
Sbjct: 216 -----AGLPLRRMGSPEEVAEAVVWLSSDAASYVVGHVLAADGG 254
>UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Congregibacter litoralis KT71|Rep: Short-chain
dehydrogenase/reductase SDR - Congregibacter litoralis
KT71
Length = 253
Score = 120 bits (290), Expect = 3e-26
Identities = 69/220 (31%), Positives = 113/220 (51%), Gaps = 2/220 (0%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++ + N+E +KV+++ + ++T E+ + ++ T+ +G+LD+ VNN
Sbjct: 31 GARVMIGDINLEQGRKVAEELSSLGDIAFVENNVTAEASCQNAVEHTVKRFGRLDIAVNN 90
Query: 89 AGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 147
AG+I ET + S + R MN N+ +++ V +L + G + P
Sbjct: 91 AGVIGETKPLLELSAEGWQRTMNININGVFFGLKAQVNQMLATGGSIINLASIASKIATP 150
Query: 148 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 207
Y SK +VD T+ AL+ A G+R+N V PGVI T L G +++ + ++
Sbjct: 151 SCADYITSKHAVDGLTKAAALDYATMGIRINSVGPGVIETPLLGTIGQTKDAQGS-IKHA 209
Query: 208 KETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
H +GR GK EVA I +LASD AS TG P++GG
Sbjct: 210 IGMHPMGRVGKVGEVANLITWLASDQASFCTGGYYPINGG 249
>UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=4; cellular organisms|Rep:
3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 268
Score = 120 bits (290), Expect = 3e-26
Identities = 70/226 (30%), Positives = 118/226 (52%), Gaps = 6/226 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
L+ +GA +++ NVE ++ + + D ++ D+T E +E +++ D G +DV
Sbjct: 42 LTDMGADVAIADVNVEKAERTASELDGETDVIATEVDVTDEGSVEAMVEDVTDRLGPIDV 101
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGI 143
LVNNAGI+E E TS+ + R+++ N+ ++ +L +G G
Sbjct: 102 LVNNAGIVENSPAEETSVESWRRVVSVNLDGVFLCAKHVGQQMLNRGEGRIVNISSMSGF 161
Query: 144 R-SFPGVLA-YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
+ P A YN +KA V T+ +A+E +GVRVN + PG + TEL E+
Sbjct: 162 DVNVPQKQASYNTTKAGVRMLTQSLAVEWGDQGVRVNAIAPGYMRTELVDE---VLEENP 218
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E E +GR G+P+E+ + +LASD +S +TG++V +DGG
Sbjct: 219 EMEETWLENTPMGRLGRPEELKELVVYLASDASSYMTGSTVVMDGG 264
>UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain
dehydrogenase/reductase SDR - Caldivirga maquilingensis
IC-167
Length = 248
Score = 120 bits (290), Expect = 3e-26
Identities = 79/251 (31%), Positives = 126/251 (50%), Gaps = 14/251 (5%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQL---SLTGRNVENLQKVSKDCDKFASTLSI 58
N +GKV L++ GA + +TG+ E ++V K +++
Sbjct: 3 NLSGKVAIVTGAGQGIGRGIALRLARDGAIVVATDITGKENEVAEEVRK---LGGQGMAL 59
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 118
D+T E++ + D YG +D+LVNNAGI + + R++N N+ ++
Sbjct: 60 RLDVTDGKMAEEVARTVFDKYGHIDILVNNAGIYPFKPFMEMTFNDWYRVINVNLNGVFN 119
Query: 119 LTMLAVPHLLESK-GXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
+T VP++++ K G G + F G+ Y+ SKA + FTR +ALELA G+
Sbjct: 120 VTRAVVPYMVKQKNGRIINIASIAGAVMGFMGLTHYSASKAGIVGFTRALALELARYGIT 179
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
VN + PG I T G SEEQ + +G+ G P+++A+ +A+LASD AS
Sbjct: 180 VNAIAPGAINTPGAATG--SEEQVRMMINAI----PMGKLGTPEDIASAVAYLASDEASY 233
Query: 237 ITGASVPVDGG 247
ITGA + +DGG
Sbjct: 234 ITGALIVIDGG 244
>UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2;
Streptomyces|Rep: Putative dehydrogenase - Streptomyces
coelicolor
Length = 255
Score = 120 bits (289), Expect = 4e-26
Identities = 75/253 (29%), Positives = 119/253 (47%), Gaps = 8/253 (3%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITAD 61
F GK L+ GA + + GR L + + ++ L++TAD
Sbjct: 6 FTGKTALVTGAGSGIGRAVALALAAEGAHVVVAGRARGPLDETAALVEQAGGKALAVTAD 65
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYLT 120
+T+ D++ ++ ++H+G LDV VNNAG+ G + + S + ++ NV ++
Sbjct: 66 VTRREDVDALVSAAVEHFGSLDVAVNNAGVFRGGVPVADLSEEDWHTQLDINVTGVFLAL 125
Query: 121 MLAVPHLLESKGXXX---XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
V H+ G + PG AY +KA+V TR AL+ GVR+
Sbjct: 126 RAEVRHMRAQPGGGTIVNIASTFGAHKRSPGATAYAATKAAVSALTRGAALDHIGDGVRI 185
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
N V+PG T + R G +E A ER ++ LGR EVAA + +LASD A+++
Sbjct: 186 NAVSPGATATSMSLRPGETE---AGRAERMRQETPLGRVSAVAEVAAAVLYLASDDAASV 242
Query: 238 TGASVPVDGGRHA 250
G + VDGG+ A
Sbjct: 243 VGTDLVVDGGQTA 255
>UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Methanospirillum hungatei JF-1|Rep: Short-chain
dehydrogenase/reductase SDR - Methanospirillum hungatei
(strain JF-1 / DSM 864)
Length = 249
Score = 120 bits (289), Expect = 4e-26
Identities = 74/223 (33%), Positives = 118/223 (52%), Gaps = 9/223 (4%)
Query: 29 GAQLSLTGRNVENLQK--VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 86
GA++ +T + E K V++ K S ++I AD+ E D++K+I K YG+LD+LV
Sbjct: 31 GAKVVITWESHEESAKNVVNEIHHKNGSAMAIQADVRNEDDVKKVINKIKGEYGRLDILV 90
Query: 87 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRS 145
NNAGI++ + T ++D L+ TN + + + A +L+ K G G+
Sbjct: 91 NNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYSRAAAKLMLKHKSGRIINISSVVGVYG 150
Query: 146 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 205
G Y+ +K+ + FT+ +A EL P G+ VN + PG I T+L + +E L
Sbjct: 151 SKGQSVYSATKSFLIAFTKSLAKELGPFGITVNAIAPGFIDTDLTH--DVKDETRQDLLS 208
Query: 206 RTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
LGR G+ D++A + FLASDL S + G + VDGG+
Sbjct: 209 HI----PLGRIGQADDIAKAVVFLASDLGSYVNGQILGVDGGQ 247
>UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Methylobacterium
extorquens PA1
Length = 282
Score = 120 bits (288), Expect = 5e-26
Identities = 71/248 (28%), Positives = 124/248 (50%), Gaps = 9/248 (3%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITAD 61
F GKV ++ GAQ+++T R E L+++ + + + ++I D
Sbjct: 38 FNGKVAFITGAASGIGRAAAIAFAREGAQVAITDRTEEALERLRAEIEGNGGAVIAIRCD 97
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLT 120
++ D+ + +T++ +G+LD NNAG+ + + +L ++DR+++ N+R +
Sbjct: 98 VSLPEDVAAAVARTVERFGRLDCAFNNAGVENKAAPVHEIALDEWDRILDINLRGTFVCM 157
Query: 121 MLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+ +L + G GIR G +Y SK ++ T+ AL+ A +RVN
Sbjct: 158 KHEIAQMLRQGGGVVVNTSSGAGIRGVAGGASYAASKHALIGLTKSAALDYAKANIRVNA 217
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
V PG I T + R + Q A LE +GR GKP+E+A + ++ SDL + +TG
Sbjct: 218 VLPGNIETPMMERFTGGDIQKAIDLE------PVGRLGKPEEIAEAVLWMCSDLGAFVTG 271
Query: 240 ASVPVDGG 247
AS+ VDGG
Sbjct: 272 ASISVDGG 279
>UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Nocardioides sp. JS614|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 258
Score = 120 bits (288), Expect = 5e-26
Identities = 72/252 (28%), Positives = 119/252 (47%), Gaps = 4/252 (1%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITAD 61
F KV L+ GA + + E+ ++ V+ D +++ A+
Sbjct: 6 FDNKVAVITGAGSGIGRAAAELLASEGAAVGVLDLRAESAEETVAAIVDSGGRAIALAAN 65
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
+ +++E I K + YG L+VL NNAG G++ + + ++R + N + + +
Sbjct: 66 VADSAEVEAAIAKVVAEYGGLNVLYNNAGCDSRGSVADATDEDWERAFSVNAKGTFVCSR 125
Query: 122 LAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
AVPHL S G + P AY +K +V TR +A++LAP+ +RVN +
Sbjct: 126 AAVPHLTASGGGAIVNQGSVAALVGVPNFAAYCAAKGAVVALTRSMAIDLAPRKIRVNVI 185
Query: 181 NPGVILTELQR--RGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
PG + T L + A L +T + +GR G P+E+A AFLASD +S +T
Sbjct: 186 CPGTVFTPLMEPMLRARGDGDLEAGLAKTLVKYPIGRLGTPEEIARVAAFLASDDSSFLT 245
Query: 239 GASVPVDGGRHA 250
G+ + DGG A
Sbjct: 246 GSVIAADGGMTA 257
>UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Sphingomonadaceae|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 266
Score = 119 bits (287), Expect = 6e-26
Identities = 72/196 (36%), Positives = 104/196 (53%), Gaps = 6/196 (3%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQ-----YDRLMNTN 112
I +L K +I+ +++KT DH+G +DVL NNA I ET + TS+ +D + N
Sbjct: 61 IACNLRKAHEIKVLMQKTADHFGGIDVLHNNAAIHETDLTDKTSIEDLPEEIWDAVYEVN 120
Query: 113 VRSIYYLTMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELA 171
+++++ T AVP L SKG G S+P AY +K V T+ A++LA
Sbjct: 121 LKALWLTTRYAVPWLKLSKGAAIVNVASTGSFVSYPQAGAYCATKGGVLLLTKATAVDLA 180
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
G+R NC PG I T + ++ + E A + H + R GKP+EVA FLAS
Sbjct: 181 KYGIRCNCYCPGAIETPMLQKYLDAAEDKKAIMSVLTGAHLIPRLGKPEEVAKLACFLAS 240
Query: 232 DLASNITGASVPVDGG 247
D +S I GAS +DGG
Sbjct: 241 DDSSFINGASYVIDGG 256
>UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 296
Score = 119 bits (287), Expect = 6e-26
Identities = 74/252 (29%), Positives = 120/252 (47%), Gaps = 10/252 (3%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST--LSI 58
++ G+V L+ GA +++ R V+ L++ + D L++
Sbjct: 41 LDLTGRVAIVTGGGTGIGAATARLLAAHGADVAVAARTVDELERTAADIRAATGRRCLAV 100
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 118
D+ E + +++++T++ G++DVLVNNAG G + + +D + NVR+ Y+
Sbjct: 101 PTDVKDEEQVIRLVRRTVEELGRIDVLVNNAGGTRMGPLSSLPTRAWDASFDLNVRAAYF 160
Query: 119 LTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
T A HL+ + G G+ G Y +KA++ FT A E GVR
Sbjct: 161 CTREAGRHLVAQRSGAIVNISSDAGLHGVRGGAHYASAKAALQMFTTVTAAEWGRYGVRA 220
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA--LGRPGKPDEVAATIAFLASDLAS 235
NC+ G + +E E A ++ ++ A LGRPG P EVA + F ASD AS
Sbjct: 221 NCLAVGPVASE-----RAVEAWRVAGIDTSEFNTATPLGRPGTPAEVANAVLFFASDAAS 275
Query: 236 NITGASVPVDGG 247
ITG ++ VDGG
Sbjct: 276 YITGQTLAVDGG 287
>UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU -
Streptomyces sp. Tu6071
Length = 244
Score = 119 bits (287), Expect = 6e-26
Identities = 76/225 (33%), Positives = 112/225 (49%), Gaps = 9/225 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA +++TGR+ + ++V K + I A+L ES ++ + + +G++DVLVN
Sbjct: 27 GADVAVTGRDEQRGRQVVKAIAEAGGVADFIAAELRGESSARRLAQAAVARFGRIDVLVN 86
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSF 146
NAG+ G E T+ A +D + NVR Y+L P + G
Sbjct: 87 NAGVFPFGPTERTTEADFDAVFGLNVRVPYFLVAELAPAMARRGHGAIVNVTTAAAAYGA 146
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 206
G+ Y SKA++ T+ A E P+GVRVN V PG TE G + A L+R
Sbjct: 147 AGLGLYGASKAALVLLTKAWAAEYGPRGVRVNAVGPGPTRTE-----GTAPR--GAALDR 199
Query: 207 TKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHAM 251
RPG +E+A I FLAS+ +S + GA +PVDGGR A+
Sbjct: 200 AALAGPARRPGTAEEIAGAIVFLASEQSSFVHGAVLPVDGGRVAV 244
>UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified
Gammaproteobacteria (miscellaneous)|Rep: Oxidoreductase
- gamma proteobacterium HTCC2207
Length = 253
Score = 119 bits (287), Expect = 6e-26
Identities = 71/228 (31%), Positives = 116/228 (50%), Gaps = 6/228 (2%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
F+S+ GA++ L N + Q + + + + D+ + +E +++ T+D +G +D
Sbjct: 25 FVSE-GAKVMLADINTDITQPLVNELGAYRCAC-VAVDVAEADQVENMVRTTVDTFGSID 82
Query: 84 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX-X 141
V V NAG + G+I +T ++ D+++ NVR ++ +P + + G
Sbjct: 83 VFVANAGTEGKIGSIMDTDVSNLDKVLAVNVRGVWLGLHYVMPVMRDGGGGSIIITSSGA 142
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR--RGGLSEEQ 199
G++ P AYN SK +V RC ALE A G+RVN VNPG + T + G +E
Sbjct: 143 GVQGSPNTAAYNTSKHAVIGLMRCAALESAQFGIRVNTVNPGAVETRMMESIEDGFAEAG 202
Query: 200 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
F + LGR G+P+E+A + FL SD +S TG+ VDGG
Sbjct: 203 AGDFRAMVEAVTPLGRYGQPEEIANMMVFLGSDDSSYCTGSVYMVDGG 250
>UniRef50_Q6MLN8 Cluster: Oxidoreductase; n=1; Bdellovibrio
bacteriovorus|Rep: Oxidoreductase - Bdellovibrio
bacteriovorus
Length = 321
Score = 119 bits (286), Expect = 8e-26
Identities = 77/224 (34%), Positives = 116/224 (51%), Gaps = 4/224 (1%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTID-HYGKLDV 84
SK G + L GRN E LQ V+ C AS +S DL+ E+ + K + + + +++
Sbjct: 96 SKNGYFVYLMGRNKERLQDVALKCRSGASIVS--CDLSDEAALNKRLGEVMGAKIHRVEC 153
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX-GI 143
+VNNAGI E+ T E+ S + R N+ + P+ E G G+
Sbjct: 154 VVNNAGIYESNTTESGSDELWSRQFEVNMLGPLRIVRAFFPYFKEQGGGSIVNISSTLGL 213
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 203
R AY+ KA++ +T +ALE P +R NCV PG++ T + + L E+Q A
Sbjct: 214 RPQGPTSAYSAVKAALVNWTESLALEGGPLNIRANCVCPGLVDTPIHQFHALPEDQKKAT 273
Query: 204 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
L++ LGR GKP+++A + FL SDL+S TGA + VDGG
Sbjct: 274 LDKMGGLQPLGRIGKPEDIARAVYFLGSDLSSWTTGAVLSVDGG 317
>UniRef50_Q333V8 Cluster: NAD or NADP oxidoreductase; n=1;
Micromonospora sp. ML1|Rep: NAD or NADP oxidoreductase -
Micromonospora sp. ML1
Length = 264
Score = 119 bits (286), Expect = 8e-26
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 4/220 (1%)
Query: 30 AQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNA 89
A + GR L++++ D +T + AD+T+ E ++ +G + LVNNA
Sbjct: 46 ANVVAVGRREAALRELTGDGGGQVAT--VAADITEPGAAEHVVAAATTRFGTVHGLVNNA 103
Query: 90 GIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGV 149
G+ T++ S +DRL+ TNVR+ L A+PHL E +G + + PG
Sbjct: 104 GLARFATLDTASDEDFDRLLATNVRAPAALIRAALPHLREHRGAVVNVSSVGAVLAMPGR 163
Query: 150 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 209
Y SKA+++ TR +A ELAP VRVN V PG + T + GL + A
Sbjct: 164 SFYGASKAALNSLTRSLARELAP-DVRVNAVLPGPVDTPMWDDMGLDSVKSALLRSSLLA 222
Query: 210 THALGRPGKPDEVAATI-AFLASDLASNITGASVPVDGGR 248
LGR G+P E+A + L + + ITGA +PVDGGR
Sbjct: 223 ATPLGRFGQPAEIAGWVCGLLDPEFSGWITGALIPVDGGR 262
>UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 259
Score = 119 bits (286), Expect = 8e-26
Identities = 71/194 (36%), Positives = 106/194 (54%), Gaps = 7/194 (3%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
+ DL++ + E+++++ + G LDVLVNNAGI +T YD + + N++ +
Sbjct: 59 VRGDLSRVPECERVVEEAAEALGGLDVLVNNAGITRALDFLDTDEETYDAIFDLNMKGYF 118
Query: 118 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
+ AVPH+LE+ G G FP AY +K ++ FTR +A+ELA +G+R
Sbjct: 119 FCARSAVPHMLEAGGGSIVNITSVHGFAGFPHHTAYAATKGAIIAFTRQLAIELAGRGIR 178
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
VN + PG+I E+ R + Y+ E+ +E GR GKP +V AFLASD A
Sbjct: 179 VNAIGPGLI--EVPRYYDI--PGYSP--EQGRELVPWGRVGKPKDVGPAAAFLASDAADF 232
Query: 237 ITGASVPVDGGRHA 250
ITG + VDGG A
Sbjct: 233 ITGQVLYVDGGTTA 246
>UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Hyphomonas
neptunium ATCC 15444|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Hyphomonas neptunium
(strain ATCC 15444)
Length = 262
Score = 119 bits (286), Expect = 8e-26
Identities = 69/248 (27%), Positives = 124/248 (50%), Gaps = 7/248 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
F KV L++ GA + L N + ++ D A +++ D+
Sbjct: 6 FENKVAVITGAASGIGAATARLLAREGAHVVLADVNDNGGKSIAADLGPTA--MAVKCDV 63
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ +++E ++K ++ +G++D+L NNAGI GT A+++R++ ++ S+YY
Sbjct: 64 SSAAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYACHF 123
Query: 123 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
A+PH+ G+ AYN +K +V +TR +A++ G+RVN + P
Sbjct: 124 AIPHMPRG-SAIVNTASISGLGGDYRFAAYNAAKGAVVNYTRALAVDHGRDGIRVNALCP 182
Query: 183 GVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASV 242
G++ T + G+ +Q E + + R +P+E+A+ +AFLASD AS +TG +
Sbjct: 183 GLVETPI--TAGV--QQMPGLREDWLKRIPMERAAQPEEMASVVAFLASDDASYVTGTIM 238
Query: 243 PVDGGRHA 250
DGGR A
Sbjct: 239 VADGGRTA 246
>UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=1;
Pseudoalteromonas haloplanktis TAC125|Rep:
7-alpha-hydroxysteroid dehydrogenase - Pseudoalteromonas
haloplanktis (strain TAC 125)
Length = 264
Score = 118 bits (285), Expect = 1e-25
Identities = 74/229 (32%), Positives = 128/229 (55%), Gaps = 14/229 (6%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 83
L+ GA + +T R +E++++ + + S L + D+ E + ++ KTI+H+G+LD
Sbjct: 31 LADAGADIVVTARTIEDIEQTAAQIRQRGSRALVVACDVLDEQQRQSLVDKTIEHFGRLD 90
Query: 84 VLVNNAGIIETGTIENT---SLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXX 138
+LVNN G +G I+ T S A+ + N + + L+ ++ PH++ + +G
Sbjct: 91 ILVNNVG--GSGAIKPTLSSSAAELENCFKLNTATAFDLSRISAPHMVNTSGQGSIINIS 148
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 198
G + PG ++Y I+KA+++ T +A + APK VRVN ++ G LTE +G +++E
Sbjct: 149 SVAGQLAQPGFISYGIAKAALNFMTLNLAQDFAPK-VRVNAISVGSTLTE-ALKGVMNDE 206
Query: 199 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
A ++RT + R G+P++VAA FLAS A ITG V+GG
Sbjct: 207 MEQAIVKRT----PMNRLGQPEDVAACALFLASPAAGYITGEIFGVNGG 251
>UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Stigmatella aurantiaca DW4/3-1|Rep: NAD-dependent
epimerase/dehydratase - Stigmatella aurantiaca DW4/3-1
Length = 263
Score = 118 bits (285), Expect = 1e-25
Identities = 71/193 (36%), Positives = 104/193 (53%), Gaps = 7/193 (3%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSI 116
+TAD+ E D+E +++ + YG+LD NNAG + IE T+ +YD +M TNVRS
Sbjct: 60 VTADVLSERDVEAMVQAALTTYGRLDGAFNNAGTSLSKPFIEMTN-DEYDTVMATNVRSA 118
Query: 117 YYLTMLAVPHLLESKGXXXXX-XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 175
++ + +L G +R+ PG+ AY+ SKA + TR VA+E A K +
Sbjct: 119 FWCMKYQLKAMLAGGGGAIVNCASVSAVRAMPGLSAYSASKAGLAALTRGVAVEYAQKNI 178
Query: 176 RVNCVNPGVILTELQRRG-GLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
R N V+PG++ +E+ G L + AF + R G P EVA +AFL SD A
Sbjct: 179 RANTVSPGIVESEMATAGWRLHDRMGRAF---ASSFQPMNRVGTPQEVAGLVAFLLSDKA 235
Query: 235 SNITGASVPVDGG 247
S +TG + VDGG
Sbjct: 236 SFLTGQDLAVDGG 248
>UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOHOL
DEHYDROGENASE; n=10; Proteobacteria|Rep:
TOLUENESULFONATE ZINC-INDEPENDENT ALCOHOL DEHYDROGENASE
- Brucella melitensis
Length = 262
Score = 118 bits (284), Expect = 1e-25
Identities = 76/254 (29%), Positives = 127/254 (50%), Gaps = 10/254 (3%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
++ GKV +K GA++ + R+ ++V+ + A L++ A
Sbjct: 11 VSLEGKVALITGAGSGFGEGMAKRFAKGGAKVVIVDRDKAGAERVAGEIGDAA--LAVAA 68
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYL 119
D++KE+D++ ++ + +GK+D+LVNNAGI + E ++DR++ NVR +Y +
Sbjct: 69 DISKEADVDAAVEAALSKFGKVDILVNNAGIGHKPQNAELVEPEEFDRIVGVNVRGVYLM 128
Query: 120 TMLAVPHLLE--SKG---XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 174
T +PH E +KG R P + YN +K V T+ +A+ELAP
Sbjct: 129 TRKLIPHFKENGAKGQECVILNVASTGAGRPRPNLAWYNATKGWVVSVTKALAIELAPAK 188
Query: 175 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
+RV +NP + E E ++ +++ +GR KPD++A AFL S A
Sbjct: 189 IRVVALNP--VAGETPLLTTFMGEDSEEIRKKFRDSIPMGRLLKPDDLAEAAAFLCSPQA 246
Query: 235 SNITGASVPVDGGR 248
S ITG ++ VDGGR
Sbjct: 247 SMITGVALDVDGGR 260
>UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=3; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Clostridium
phytofermentans ISDg
Length = 258
Score = 118 bits (284), Expect = 1e-25
Identities = 70/252 (27%), Positives = 121/252 (48%), Gaps = 9/252 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITA 60
+ GKV +K GA ++L R +E L +V + +K +++
Sbjct: 6 DLTGKVAVVTGASSGLGADAALAYAKAGADVALLARRIEKLNEVKAEIEKIGRKVVAVGC 65
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+T E ++ ++ ID +G +D+L+NNAGI G +++ S+ +D+ +TNV+ I+ +
Sbjct: 66 DVTNEESVKTAMQTVIDTFGHIDILLNNAGIAVRGGVDSMSVEDWDKSYDTNVKGIFLAS 125
Query: 121 MLAVPHLLE---SKGXXXXXXXXXGIRSFPGVL--AYNISKASVDQFTRCVALELAPKGV 175
VP + E K F + +YN SKA+V TR +A A G+
Sbjct: 126 KYVVPQMKERGYGKIINIASVNAVVADKFDAFIRHSYNSSKAAVVGLTRGMAASYARYGI 185
Query: 176 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
VN + P + +E+ E+ FL + + GRPG+ E+ T+ +L+SD +S
Sbjct: 186 TVNAIGPALFESEMTSDTLFKSEE---FLNKYNTMNPAGRPGRKGELNGTVLYLSSDSSS 242
Query: 236 NITGASVPVDGG 247
+ G + VDGG
Sbjct: 243 YVQGQFIIVDGG 254
>UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=32; cellular organisms|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Methanosarcina acetivorans
Length = 256
Score = 118 bits (284), Expect = 1e-25
Identities = 75/251 (29%), Positives = 122/251 (48%), Gaps = 7/251 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
F GKV ++ GA ++LT N Q V + + L+I D+
Sbjct: 9 FLGKVAFVTGGATGIGQATAVAFAREGANVALTYHNQGAEQTVRRIEELGGQALAIKCDV 68
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
+E D++ I+K I +G+LD NNAGI +T + +++R++ TN+ ++
Sbjct: 69 IREEDVKNAIEKIIQTFGQLDYAFNNAGIEGKTVITAEYPVEEWNRVIATNLTGVFLCMK 128
Query: 122 LAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
+P +L + G G+ FP + Y SK V T+ AL+ A +R+N V
Sbjct: 129 YEIPQMLKQGAGAIVNCSSGAGLTGFPDISPYVASKHGVVGLTKTAALDYAKSNIRINAV 188
Query: 181 NPGVILTE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
PG+ T ++R G + E Y E+ E +GR G+P+E+A + +L SD AS +TG
Sbjct: 189 CPGMTDTPMMERYSGGTPEGY----EKIIEQEPIGRMGRPEEIAIAVLWLCSDAASFVTG 244
Query: 240 ASVPVDGGRHA 250
+ VDGG+ A
Sbjct: 245 DVMRVDGGQLA 255
>UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=33; Bacteria|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family - Shewanella oneidensis
Length = 254
Score = 118 bits (283), Expect = 2e-25
Identities = 76/248 (30%), Positives = 123/248 (49%), Gaps = 9/248 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKD--CDKFASTLSIT 59
N GKV L+ GA ++ T + E ++ D + ++I
Sbjct: 11 NLQGKVAFVQGGSRGIGAAIVKRLASEGAAVAFTYVSSEAQSQLLVDEVIAQGGKAIAIK 70
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
AD T+ I + I++T H G LD++VNNAGI+ +IEN +L ++R++NTNVRS++
Sbjct: 71 ADSTEPEAIRRAIRETKAHLGGLDIVVNNAGILIWDSIENLTLEDWERIVNTNVRSVFVA 130
Query: 120 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+ A H+ + F G Y +SK+++ + +A +L P+ + VN
Sbjct: 131 SQEAALHMNDGGRIINIGSTNAERIPFVGGAIYGMSKSALVGLAKGLARDLGPRAITVNN 190
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
+ PG + T++ G S E K LGR GK +E+A+ +AF+A A ITG
Sbjct: 191 IQPGPVDTDMNPDNGDSSEP-------IKAIGVLGRYGKAEEIASFVAFIAGPEAGYITG 243
Query: 240 ASVPVDGG 247
AS+ +DGG
Sbjct: 244 ASLMIDGG 251
>UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein;
n=2; Streptomyces|Rep: Ketoacyl ACP/CoA reductase-like
protein - Streptomyces natalensis
Length = 257
Score = 118 bits (283), Expect = 2e-25
Identities = 74/253 (29%), Positives = 124/253 (49%), Gaps = 17/253 (6%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADL 62
+GKV ++ GA + L R V+ L+ + + + A I D+
Sbjct: 9 SGKVSLITGASSGIGAATARLFAREGAAVVLAARRVDRLRALVSEIRRTGAEAAYIATDV 68
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
++E D+ + ++ T++ YG+LD+ NNAG+ + ++ YD +M TNVR +++
Sbjct: 69 SQEEDVRRAVEFTVEKYGRLDLAFNNAGVGCDHESMHLMQQDTYDDVMGTNVRGVWHCLQ 128
Query: 122 LAVPHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+ +L + G G+++ P Y SK +V T+ A E AP+G+RVN
Sbjct: 129 HEISAMLHNGVGGSIVNNSSVAGLQAIPAGAPYIASKHAVIGLTKAAAAEYAPQGIRVNS 188
Query: 180 VNPGVILTEL-----QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
V PG TE+ R GL E+ + A + R +P+E+A +A+L SD +
Sbjct: 189 VAPGTTRTEIIAGWFDRNPGLEEQLHRATPQ--------ARTAEPEEIAQAVAWLCSDRS 240
Query: 235 SNITGASVPVDGG 247
S +TGA +PVDGG
Sbjct: 241 SFVTGAVLPVDGG 253
>UniRef50_Q1Q261 Cluster: Strongly similar to
3-oxoacyl-[acyl-carrier protein] reductase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Strongly
similar to 3-oxoacyl-[acyl-carrier protein] reductase -
Candidatus Kuenenia stuttgartiensis
Length = 239
Score = 118 bits (283), Expect = 2e-25
Identities = 71/211 (33%), Positives = 116/211 (54%), Gaps = 8/211 (3%)
Query: 39 VENLQKVSKDCDKFASTLSIT-ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI 97
+++++K+ ++ + SI AD+T + I++++ + +GK+DVL+NNAGII+ G I
Sbjct: 33 IDDIEKLREEFSSPQGSFSIEKADVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYI 92
Query: 98 ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISK 156
S ++ ++N N+ ++ T H++ + G GI PG Y+ +K
Sbjct: 93 MLMSAKDWNDVINVNLTGVFNCTKAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAK 152
Query: 157 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRP 216
V FT ++ ELAP +RVN V PGVI T++ L + + ++ KE L R
Sbjct: 153 GGVIAFTMALSKELAPFCIRVNTVAPGVIETDI--IDSLDKNKRNSY----KEHIPLKRF 206
Query: 217 GKPDEVAATIAFLASDLASNITGASVPVDGG 247
GKP+EVA+ + FLAS AS ITG + V GG
Sbjct: 207 GKPEEVASVVRFLASSEASYITGEVIRVSGG 237
>UniRef50_Q1BBB6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Mycobacterium sp. (strain MCS)
Length = 266
Score = 118 bits (283), Expect = 2e-25
Identities = 76/221 (34%), Positives = 115/221 (52%), Gaps = 3/221 (1%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA+L +T E L ++ + + + + D++ E D ++I +D +G+LDVLV
Sbjct: 43 GARLVVTDIQSEPLLALADELRHAGADVEPVVGDVSVEYDAGRMIGAAVDRFGRLDVLVA 102
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXX-XXXXXGIRSF 146
NAGII G + A +D +M + R ++ A+ +L + G G+
Sbjct: 103 NAGIIPLGDALEMTAAGWDEVMAIDGRGMFLCCKFAIEAMLPTGGGAIVCLSSISGLAGQ 162
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 206
AY +K T+ +A+E A +G+RVN V PG I TE +R E + +L
Sbjct: 163 KRQAAYGPAKFIATGLTKHLAVEWADRGIRVNAVAPGTIRTERVKRFP-EEPGGSEYLAA 221
Query: 207 TKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ H +GR G+P EVA+ I FLASD AS ITGA +PVDGG
Sbjct: 222 VERMHPMGRIGEPAEVASAIVFLASDDASFITGAVLPVDGG 262
>UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 269
Score = 118 bits (283), Expect = 2e-25
Identities = 79/256 (30%), Positives = 118/256 (46%), Gaps = 16/256 (6%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV L+ GA + + E + ++ D A +++ DL +
Sbjct: 10 GKVAIVTGGAGGIGEATARLLTARGACVVIADIAFERAEALAAD---LAGAIALPLDLEQ 66
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGII------ETGTIENTSLAQYDRLMNTNVRSIYY 118
E +E ++++T+ H+G+LDVL NNA ++ G +E A +DR NVR
Sbjct: 67 EQSVETLVERTVAHFGRLDVLHNNAALLGPEIAQADGDVERMGTALWDRTFAVNVRGTMI 126
Query: 119 LTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
A+PHL E++G ++ AY+ SKA+V Q TR +A GVR N
Sbjct: 127 ACRAALPHLRETRGCIVNTVSNLALQGHLIQAAYSSSKAAVIQMTRAIAASHGKAGVRCN 186
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHAL-GRPGKPDEVAATIAFLASDLASNI 237
V PG+ +T R E + L + E L R G P ++A IAFLASD A N+
Sbjct: 187 AVAPGMTMTPALR------EAFPPALRQVVEDETLRDRLGDPRDIAEAIAFLASDAARNV 240
Query: 238 TGASVPVDGGRHAMCP 253
TG + DGG + P
Sbjct: 241 TGQVLVCDGGGASHVP 256
>UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus
sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp.
B14905
Length = 252
Score = 118 bits (283), Expect = 2e-25
Identities = 70/227 (30%), Positives = 121/227 (53%), Gaps = 6/227 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L+ GA++ + N E ++ K ++ + + AD++K D+EK + ++ YG++D
Sbjct: 25 LASNGAKVVIVDFNKETGEETLKLVKEQGGEGIFVQADVSKSEDVEKYVNAAVETYGRID 84
Query: 84 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX--XXXXX 140
V NNAG+I+ + + ++YDR+M+ NV+ + +L + V ++E +G
Sbjct: 85 VFFNNAGVIQKISPLTEIADSEYDRIMSINVKGV-FLGLKHVIKVMEGQGSGSIINTAST 143
Query: 141 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 200
G+RS + Y+ SK +V T+ +LE KG+R+N + PG + T L E
Sbjct: 144 AGVRSEHSMAVYSASKHAVIGLTKSASLEYVKKGIRINAICPGGVETALTNSVTAMFET- 202
Query: 201 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
++ +GR KP+E+A + FLASD AS +TG+ V VDGG
Sbjct: 203 GGYIPEEIPNMRMGRYAKPEELAEMVVFLASDKASYMTGSIVVVDGG 249
>UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Polaromonas
naphthalenivorans (strain CJ2)
Length = 286
Score = 118 bits (283), Expect = 2e-25
Identities = 73/204 (35%), Positives = 107/204 (52%), Gaps = 19/204 (9%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVR 114
L + D+T E +E + ++ +G++D LVNNAGI +TG S+ +DR++ ++R
Sbjct: 68 LGLGCDVTSEESVEAAVAAVLERFGRIDALVNNAGIGDQTGPTTEQSVQAFDRVLAVHLR 127
Query: 115 SIYYLTMLAVPHLLES-------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 167
+ ++ H+L++ +G P AY+ KA V TR +A
Sbjct: 128 GTFLMSRAVARHMLQAAPVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGMTRAMA 187
Query: 168 LELAPKGVRVNCVNPGVILT----ELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVA 223
E A G+RVN V PG + T EL+R+G + AA RT LGR +P E+A
Sbjct: 188 SEWARAGIRVNAVAPGYVRTALVAELERKGAIDA---AAIRRRTP----LGRMAEPAEIA 240
Query: 224 ATIAFLASDLASNITGASVPVDGG 247
IAFLASD AS +TGA +PVDGG
Sbjct: 241 EVIAFLASDRASYVTGALIPVDGG 264
>UniRef50_Q2G4A5 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Novosphingobium aromaticivorans DSM
12444|Rep: Short-chain dehydrogenase/reductase SDR
precursor - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 246
Score = 117 bits (282), Expect = 3e-25
Identities = 74/247 (29%), Positives = 120/247 (48%), Gaps = 6/247 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
M F + V + GA+L++TGRN E L+ V+++ D L I +
Sbjct: 1 MRFRDRCVAILGGNAGIGLAAARLFAAEGAKLAITGRNAETLRAVAEELD----ALCIRS 56
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+ +D E+ +++ D G +DVL NAG+ + + + +D++ + N+R ++
Sbjct: 57 DMGDLNDTERALEEIEDALGGIDVLFVNAGVGGFAMVPDVTPEFWDQIHSVNLRGAFFAI 116
Query: 121 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
A+P L+ G + + PG +AY +KA + R V EL P+ +RVN V
Sbjct: 117 QRALP-LMRDGGSIVITGSIGSMAAVPGNVAYAAAKAGLRAMARIVGKELLPRRIRVNMV 175
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
+PG TE+ +R S E+ + +GR G +EVA + FLAS AS I G
Sbjct: 176 SPGPTDTEIFKRDA-SAEEIQGMKDMLSSVVPIGRMGTSEEVARAVLFLASAEASFINGV 234
Query: 241 SVPVDGG 247
+ VDGG
Sbjct: 235 DLCVDGG 241
>UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Roseovarius sp. 217
Length = 256
Score = 117 bits (282), Expect = 3e-25
Identities = 72/231 (31%), Positives = 119/231 (51%), Gaps = 5/231 (2%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
FLS+ GA+++L +V++L + D L+I AD++ D ++ + +T++ +G++D
Sbjct: 26 FLSE-GAKVALVDLHVDDLSDAAGDLGNPDDLLTIAADVSSVEDCKRYVAQTVEKFGRID 84
Query: 84 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 141
V NNAG+ + + + +DR+M NVR + +P + + G
Sbjct: 85 VFFNNAGVEGMVAPLVDQKIEDFDRVMAVNVRGAFLGLQHVLPVMTGQQSGSVINMSSIA 144
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR--RGGLSEEQ 199
G++ P V Y SK +V TR A+E+A VRVN V+P + T + R G +
Sbjct: 145 GLKGSPNVAPYITSKHAVVGLTRAAAIEVAGHNVRVNSVHPSPVNTRMMRSLEEGFNPGH 204
Query: 200 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHA 250
++ T LGR G+ E+A + FLASD ++ ITGA P+DGG A
Sbjct: 205 GDEVKQQLAGTIPLGRYGESIEIANLVLFLASDESAFITGAQYPIDGGMSA 255
>UniRef50_Q982N5 Cluster: 3-ketoacyl-acyl carrier protein reductase;
n=1; Mesorhizobium loti|Rep: 3-ketoacyl-acyl carrier
protein reductase - Rhizobium loti (Mesorhizobium loti)
Length = 256
Score = 117 bits (281), Expect = 3e-25
Identities = 70/193 (36%), Positives = 104/193 (53%), Gaps = 7/193 (3%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
I D+++ D E + + +G+LD++V NAGI IENTS +DR+M N+R +
Sbjct: 56 IGTDISQMRDAEASVALALKRHGRLDIIVQNAGIYPWQLIENTSTDDWDRVMAVNLRGTF 115
Query: 118 YLTMLA-VPHLLESKGXXXXXXXXXGIR-SFPGVLAYNISKASVDQFTRCVALELAPKGV 175
T A VP + G G + PG Y+ +KA ++ F R ALE + G+
Sbjct: 116 NATRAALVPMKAQRSGRMLYTSSITGPHVTSPGHGHYSATKAGINGFIRAAALEFSGYGI 175
Query: 176 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
VN V PG ILTE + + + AA+++ +++ LGR G P +VA FLASD A
Sbjct: 176 TVNGVEPGNILTE-----AIQQHRGAAYIKNMEDSIPLGRLGSPRDVANAFLFLASDDAG 230
Query: 236 NITGASVPVDGGR 248
ITG ++ VDGG+
Sbjct: 231 YITGTTIVVDGGQ 243
>UniRef50_Q8R9W0 Cluster: Dehydrogenases with different
specificities; n=4; Bacteria|Rep: Dehydrogenases with
different specificities - Thermoanaerobacter
tengcongensis
Length = 247
Score = 117 bits (281), Expect = 3e-25
Identities = 73/226 (32%), Positives = 125/226 (55%), Gaps = 9/226 (3%)
Query: 25 LSKLGAQLSLTG-RNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKL 82
L+K G +++T ++ ++ ++V ++ K L+I D++K ++EK ++K I+ +G +
Sbjct: 25 LAKDGFNIAITYVKDDKSAEEVVEEVKKHGVDALAIKCDVSKYHEVEKAVEKVIEEFGSI 84
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 141
DV+VNNAGI + I ++D++++ N++ + + A ++++ KG
Sbjct: 85 DVVVNNAGITKDNLILKMEEEEWDQVIDVNLKGAFNVIKFASKYMIKKRKGKIINISSVV 144
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G+ G Y SKA + T+ VA ELA +G+ VN V PG I T++ L E+
Sbjct: 145 GLMGNVGQANYAASKAGIIGLTKSVAKELASRGITVNAVAPGFIETDM--TNVLKEDIKE 202
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
A L ++ L R GKP+EVA +AFLAS + ITG + VDGG
Sbjct: 203 AML----KSIPLKRAGKPEEVAEVVAFLASSASDYITGQVINVDGG 244
>UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 306
Score = 117 bits (281), Expect = 3e-25
Identities = 73/196 (37%), Positives = 103/196 (52%), Gaps = 11/196 (5%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLA---QYDRLMNTN 112
+++ D+T DIE++I +D +GKLDVL NNAG TG I + A +D +M N
Sbjct: 114 IAVHVDVTSTEDIERMITTAVDRFGKLDVLYNNAGF--TGPIVPLAEAGEDYFDAVMAVN 171
Query: 113 VRSIYYLTMLAVPHLLESKGXXXX-XXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
V+ +Y A+P +L G G+ + G+ Y +K +V Q TR AL+ A
Sbjct: 172 VKGVYLGMKAAIPVMLAGGGGSIINTASAAGLVGWKGLAVYAATKGAVVQLTRSAALDYA 231
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
KG+RVN V PG T R+ ++ E + R G PDE+AA FLAS
Sbjct: 232 AKGIRVNAVCPGATWT---RQADAEDDSLPP--EGVVPPQPMRRWGMPDELAAAALFLAS 286
Query: 232 DLASNITGASVPVDGG 247
D AS +TG ++PVDGG
Sbjct: 287 DDASFVTGVALPVDGG 302
>UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Roseiflexus sp. RS-1
Length = 246
Score = 117 bits (281), Expect = 3e-25
Identities = 73/249 (29%), Positives = 118/249 (47%), Gaps = 8/249 (3%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSIT 59
M GKV ++ GA +++ N+ + + + L++
Sbjct: 1 MRLKGKVAIVTGAGHGIGKATAIAFAREGAHVAVVDINMAGAEATVAEITRLDGRALAVQ 60
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
AD+++ + +E +++ + G++DVL+NNAGI + + Q+D ++N N++ ++
Sbjct: 61 ADVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLVKMTEQQWDAVINVNLKGVWLC 120
Query: 120 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
PH+ + G G+ G Y +K V T+ A EL P GVRVN
Sbjct: 121 ARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWARELGPSGVRVN 180
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
V PG I TE+ + E+ ERT L R GKP+EVAA FLASD +S +T
Sbjct: 181 AVTPGFIATEMITT--IPEKVIQTVCERT----PLRRLGKPEEVAAVYVFLASDESSFMT 234
Query: 239 GASVPVDGG 247
G+ + VDGG
Sbjct: 235 GSVIQVDGG 243
>UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 260
Score = 117 bits (281), Expect = 3e-25
Identities = 79/255 (30%), Positives = 123/255 (48%), Gaps = 11/255 (4%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST--LSITA 60
F GKV L GA + + RN +N+ + + T I
Sbjct: 8 FEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAG 67
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYL 119
+ D +K++ T+ +GK+++LVNN GI G I S +D+L NV++ + +
Sbjct: 68 HIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQM 127
Query: 120 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
T L PH+ E G +S PG+ AY ++K ++ TR +A+ LA +RVN
Sbjct: 128 TKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVN 187
Query: 179 CVNPGVILTELQR---RGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
+ PGVI T++ + GG E+ ++ ALGR G PD+ A T+A+LASD +S
Sbjct: 188 GIAPGVIKTKMSQVLWDGGEDAEKELTDIQEI----ALGRLGVPDDCAGTVAYLASDDSS 243
Query: 236 NITGASVPVDGGRHA 250
ITG + + GG A
Sbjct: 244 YITGEMIIIAGGVQA 258
>UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain
dehydrogenase/reductase family; n=1; Photobacterium
profundum|Rep: Hypothetical oxidoreductase, short-chain
dehydrogenase/reductase family - Photobacterium
profundum (Photobacterium sp. (strain SS9))
Length = 255
Score = 116 bits (280), Expect = 4e-25
Identities = 75/246 (30%), Positives = 121/246 (49%), Gaps = 5/246 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLT 63
AGKV S+ GA L L RN Q ++++ + TL I AD+T
Sbjct: 8 AGKVALISGITSGIGEATARLFSQQGASLVLVARNENKGQMLAEELNAQYPTLFIKADIT 67
Query: 64 KESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ + ++++ ++T+ +G +D NNAGI I TS +++++NTN+ + +
Sbjct: 68 QANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLNR 127
Query: 123 AVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
+ + + G + + P AYN S+ +V TR A+E A +GVRVN V
Sbjct: 128 QLSIMSKQGHGTIVNMASICSVLARPNRAAYNTSRHAVLGLTRSAAVEYAKQGVRVNAVA 187
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG I T + R + Q A + + H +GR G+P EVA +L SDL+S + G +
Sbjct: 188 PGAIDTPIFERSTQKDPQLIA---KYHQAHPIGRIGQPREVAEAALWLCSDLSSFVVGHT 244
Query: 242 VPVDGG 247
+ VDGG
Sbjct: 245 LMVDGG 250
>UniRef50_P50162 Cluster: Tropinone reductase 1; n=77;
Viridiplantae|Rep: Tropinone reductase 1 - Datura
stramonium (Jimsonweed) (Common thornapple)
Length = 273
Score = 116 bits (280), Expect = 4e-25
Identities = 78/231 (33%), Positives = 124/231 (53%), Gaps = 13/231 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHY--GK 81
L+ LGA++ RN + L + + +K + DL ++ +K+++ T+ H GK
Sbjct: 41 LAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSRTERDKLMQ-TVAHVFDGK 99
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 140
L++LVNNAG++ ++ + Y+ +M TN + Y+L+ +A P L S+ G
Sbjct: 100 LNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSI 159
Query: 141 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ----RRGGLS 196
G + P V Y+ SK +++Q T+ +A E A +RVN V PGVILT L ++
Sbjct: 160 AGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQ 219
Query: 197 EEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+E+ F+ +T +GR GKP EV+A IAFL AS ITG + DGG
Sbjct: 220 KEEIDNFIVKT----PMGRAGKPQEVSALIAFLCFPAASYITGQIIWADGG 266
>UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus
iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis
Length = 248
Score = 116 bits (279), Expect = 6e-25
Identities = 73/224 (32%), Positives = 116/224 (51%), Gaps = 10/224 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
L+ LGA + + R E+ Q+V++ + A + D+TKE + + + + I+ +G+LDV
Sbjct: 26 LASLGAIVGVAARKDEDAQEVAEMIGE-AHAFPVQLDVTKELEWKTAVDEIINKFGRLDV 84
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGI 143
LVNNAG ++ + T+L Y +L+N N ++ +P + + KG
Sbjct: 85 LVNNAGALKRKPFKETTLDDYQQLINVNQLGVFMGMQAVIPQMEKQQKGSIINNVSISAF 144
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 203
AY +K+SV ++ A+EL P G+RVN V+PG I T++ + E A+
Sbjct: 145 APISQSSAYAATKSSVVAMSKAAAIELGPAGIRVNMVHPGGIKTDMVTQ----TEDVPAY 200
Query: 204 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
L R G+P E+A IAFLASD +S TG + VDGG
Sbjct: 201 YNSV----PLKRIGQPVEIAKAIAFLASDESSYCTGTELVVDGG 240
>UniRef50_Q46UI8 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Ralstonia eutropha JMP134|Rep: Short-chain
dehydrogenase/reductase SDR - Ralstonia eutropha (strain
JMP134) (Alcaligenes eutrophus)
Length = 272
Score = 116 bits (279), Expect = 6e-25
Identities = 72/227 (31%), Positives = 123/227 (54%), Gaps = 8/227 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA++++ NV+ +V+ D ++I AD++K++D E + ++T++ +G +D
Sbjct: 27 LAREGARIAVVDLNVDAATRVASSIDPDGKRAIAIRADISKKADTEAMARQTLEAFGTID 86
Query: 84 VLVNNAGIIETGTIE-NTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXX 141
+LVNNAG+ + + + +DR+M N + I + +P + + KG
Sbjct: 87 ILVNNAGVGGASALACDVTEENWDRVMGVNAKGILFCCQAVIPAMKAQGKGKIVNIDSIA 146
Query: 142 GIR-SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 200
GIR ++ + Y SK +V T+ +A ELA + + VN V PG ILT +E++
Sbjct: 147 GIRMAYFSSVDYTASKHAVTGLTQHLAWELADQRINVNAVCPGGILTPAIEAYASAEKRE 206
Query: 201 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
A + T LGR KP+E+ ++FLASD A ITG + VDGG
Sbjct: 207 ALI----RRTVPLGRFCKPEEIGEAVSFLASDRADMITGQLLAVDGG 249
>UniRef50_Q3W8G5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 249
Score = 116 bits (279), Expect = 6e-25
Identities = 73/246 (29%), Positives = 121/246 (49%), Gaps = 9/246 (3%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV L++ GA S+ +V +K + + ++ + + + D+T+
Sbjct: 6 GKVAIVTGAGIGQGRSTALRLAREGA--SVVAADVSGAEKETAEGNE--AIVPLHTDVTR 61
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGI--IETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+++E ++++T + +G+LD+L N G+ I + + +++D L+N N++S+
Sbjct: 62 AAEVEALVRETTERFGRLDILCNVVGVAGIAQAPVPDIEESEFDLLVNINLKSVLLGMKY 121
Query: 123 AVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
A+P ++ G G + S P Y +KA + TR A E GVRVN +
Sbjct: 122 AIPAMVAGGGGSIVNWSSVGALVSSPNTAVYGATKAGILSMTRAAAREWGRSGVRVNAIC 181
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG + G E++Y AL RPG PDE+AA AFLASD AS +TG+
Sbjct: 182 PGFVYPTGMTLMG--EKEYPQAFRNASAKAALDRPGHPDEIAAVAAFLASDDASFMTGSH 239
Query: 242 VPVDGG 247
V VDGG
Sbjct: 240 VVVDGG 245
>UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5;
Proteobacteria|Rep: Short chain dehydrogenase -
Janthinobacterium sp. (strain Marseille) (Minibacterium
massiliensis)
Length = 278
Score = 116 bits (279), Expect = 6e-25
Identities = 82/230 (35%), Positives = 114/230 (49%), Gaps = 16/230 (6%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
G +++++GR E ++ + + + AD+ E+D+ ++++T+ +G++DV VN
Sbjct: 56 GYRVAVSGRREEAGNALAAELRALGNEAEFLLADVRFEADVRNLVEQTVVRFGRIDVAVN 115
Query: 88 NAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPH-----LLESKGXXXXXXXXX 141
NAG + I S A Y NV TML++ H L + G
Sbjct: 116 NAGTEGQLAPIVEQSAANYAETFGVNVLG----TMLSLKHEMRVMLAQGSGSIINLSSVA 171
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE-LQRRGGLSEEQY 200
G G Y SK +V+ T+ ALE A GVRVN V PG + TE L R G SEE
Sbjct: 172 GKVGIAGASVYVASKHAVEGLTKSAALEGAAAGVRVNAVAPGPVATEMLDRFVGGSEENK 231
Query: 201 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHA 250
A FL T GR PDE+A TI FLASD S +TG S+ VDGG A
Sbjct: 232 AGFLA----TIPAGRAATPDEIAQTIVFLASDKVSYLTGQSIAVDGGHTA 277
>UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|Rep:
Glucose 1-dehydrogenase - Thermoplasma volcanium
Length = 261
Score = 116 bits (279), Expect = 6e-25
Identities = 68/199 (34%), Positives = 104/199 (52%), Gaps = 7/199 (3%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+T E ++++ ++KT YG++D+LVNNAGI + + T + R+++ NV Y +
Sbjct: 53 DVTNEEEVKEAVEKTTKKYGRIDILVNNAGIEQYSPLHLTPTEIWRRIIDVNVNGSYLMA 112
Query: 121 MLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+P +L G + AY SK ++ TR VA++ APK +R N
Sbjct: 113 KYTIPVMLAIGHGSIINIASVQSYAATKNAAAYVTSKHALLGLTRSVAIDYAPK-IRCNA 171
Query: 180 VNPGVILTEL-----QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
V PG I+T + + G E +E H +GR G+P+EVA +AFLASD +
Sbjct: 172 VCPGTIMTPMVIKAAKMEVGEDENAVERKIEEWGRQHPMGRIGRPEEVAEVVAFLASDRS 231
Query: 235 SNITGASVPVDGGRHAMCP 253
S ITGA + VDGG + P
Sbjct: 232 SFITGACLTVDGGLLSKLP 250
>UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Short-chain alcohol
dehydrogenase - Cenarchaeum symbiosum
Length = 252
Score = 116 bits (279), Expect = 6e-25
Identities = 75/253 (29%), Positives = 125/253 (49%), Gaps = 7/253 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
M GKV L++ GA++ L GR + L+ + ST SI
Sbjct: 1 MRLEGKVAVVTGASSDIGASIVRRLAEEGAKVVLLGRRPDALEAARRVSGHEESTASIPC 60
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+T E + ++ + ++ YG++D+LVN AG I + + ++++ NV +
Sbjct: 61 DVTDEGQLAQMADRVVEAYGRIDILVNGAGSIHDPKHFHVMPIMDVKKMIHGNVLGVLLP 120
Query: 120 TMLAVPHLLESKGXXXXXXXXXGIRSFPGV--LAYNISKASVDQFTRCVALELAPKGVRV 177
T + ++++ G R+ P V AY+ +KA+V FT+ +A+E A + +R
Sbjct: 121 TRAVLGKMMDTGGVIINIGSISAERAIPRVHLAAYSSTKAAVVMFTKSIAVEYARRNIRC 180
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
NC+NPG++ + + + L + LE E L R G P ++A + FLASD AS I
Sbjct: 181 NCINPGIVDSGM-IKPYLEDPDARRILE---ERQPLKRIGTPADIANAVLFLASDEASWI 236
Query: 238 TGASVPVDGGRHA 250
TGA + VDGG+ A
Sbjct: 237 TGAVLNVDGGKSA 249
>UniRef50_A0HJB5 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Comamonas testosteroni KF-1|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Comamonas testosteroni KF-1
Length = 249
Score = 116 bits (278), Expect = 8e-25
Identities = 65/188 (34%), Positives = 100/188 (53%), Gaps = 6/188 (3%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D++ E ++++ +DHYG++D LV +AGI G +E+ +L ++++++ N+
Sbjct: 58 DVSSEKLTQELVASMLDHYGQIDGLVTSAGISRVGDLESMALQEWEQVLQVNLTGTMLSA 117
Query: 121 MLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
H+ + + G G+ P LAY SK +V Q R +A EL P GVRVN
Sbjct: 118 RAVASHMKQRRQGSIVAIASINGMLGNPSNLAYCTSKGAVIQMVRSLAAELGPCGVRVNS 177
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
++PG I T + L E+ E H L R GK EV +AFL SD++S ITG
Sbjct: 178 ISPGYIHTPMTIM--LDEQPVGQAFEAM---HLLKRAGKSQEVGNAVAFLLSDMSSFITG 232
Query: 240 ASVPVDGG 247
++PVDGG
Sbjct: 233 VNLPVDGG 240
>UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Candidatus Methanoregula boonei 6A8|Rep:
Short-chain dehydrogenase/reductase SDR - Methanoregula
boonei (strain 6A8)
Length = 253
Score = 116 bits (278), Expect = 8e-25
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Query: 54 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNV 113
S ++I AD+T E +++++ ++ + YG+LD+LVNNAGI++ + T + +Y +M+ N
Sbjct: 62 SAMAIRADVTCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNC 121
Query: 114 RSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 172
+ + T A ++ K G G+ G AY SK+ V FT+C A EL
Sbjct: 122 KGTFLCTQHAAKIMVRQKAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAKELGA 181
Query: 173 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 232
+ VN V PG I T+ L+ + + E + ALGR G PD+VA I FL SD
Sbjct: 182 FNITVNAVAPGFIDTD------LTADTRSQVKEDILKNIALGRIGTPDDVAKVIVFLGSD 235
Query: 233 LASNITGASVPVDG 246
LA ++G + VDG
Sbjct: 236 LAGYVSGQVIGVDG 249
>UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Geobacter metallireducens GS-15|Rep: Short-chain
dehydrogenase/reductase SDR - Geobacter metallireducens
(strain GS-15 / ATCC 53774 / DSM 7210)
Length = 266
Score = 115 bits (277), Expect = 1e-24
Identities = 75/227 (33%), Positives = 116/227 (51%), Gaps = 5/227 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA + +T N E +++ + S+ +D +E+DI+ + D +G +D
Sbjct: 37 LAEAGATVLITDINREAIEEAEHRLSSMKCKVKSLVSDAGREADIKSLFSYVADSFGGVD 96
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE--SKGXXXXXXXXX 141
+LVNNAGI I + SL Q+ ++ N+ S + + A ++ + G
Sbjct: 97 ILVNNAGIYPATKILDMSLEQWREVIRINLESAFLCSQEAGRIMVRQGTGGVIVNISSMA 156
Query: 142 GIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 200
++ FPG+ Y SK V TR ALELAP +R V PG ILT R L + +
Sbjct: 157 ALKPCFPGLAHYGASKGGVVNLTRSTALELAPHKIRAVAVVPGGILTG-GVRSNLKQSEE 215
Query: 201 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
L+ T LG G+PD++A T+ FLASD A+ ITG ++ VDGG
Sbjct: 216 KDSLQSIGATIPLGGFGQPDDIARTVLFLASDSAAYITGTTILVDGG 262
>UniRef50_Q13GE7 Cluster: Putative short-chain
dehydrogenase/reductase; n=1; Burkholderia xenovorans
LB400|Rep: Putative short-chain dehydrogenase/reductase
- Burkholderia xenovorans (strain LB400)
Length = 255
Score = 115 bits (277), Expect = 1e-24
Identities = 65/195 (33%), Positives = 106/195 (54%), Gaps = 4/195 (2%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 116
++ D+T + I++++++TID YG++DVLVNN G+ G + + + +DR + N++S+
Sbjct: 55 ALLCDVTDPASIDRVVRETIDAYGRIDVLVNNVGVSAPGGVVDMTEEIWDRQFDINLKSV 114
Query: 117 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG--VLAYNISKASVDQFTRCVALELAPKG 174
+ + +P + +G + G +AY+ SKA++ QFTR AL +
Sbjct: 115 FLMCKAVLPLMDRQRGGNVVNVSSLSALRYSGKPQIAYSASKAALIQFTRMAALMHSEHN 174
Query: 175 VRVNCVNPGVILTELQRR--GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 232
VR+NCV PG+I T L +R Y ++L+R L + G +VA AFLASD
Sbjct: 175 VRLNCVIPGLITTPLVQRLAQQFGGGDYESYLKRRNAQVPLAQEGDAWDVANATAFLASD 234
Query: 233 LASNITGASVPVDGG 247
A IT + VDGG
Sbjct: 235 EARYITATEILVDGG 249
>UniRef50_A3Q322 Cluster: Short-chain dehydrogenase/reductase SDR;
n=9; Mycobacterium|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium sp. (strain
JLS)
Length = 268
Score = 115 bits (277), Expect = 1e-24
Identities = 71/228 (31%), Positives = 111/228 (48%), Gaps = 11/228 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
L+ GA++++ R+ + ++ L I D+ + + + + +T+ G + +
Sbjct: 32 LAAFGARVAIWERDADRCAVAAES----VGGLGIVTDVRESAAVTAALDRTVAELGTVTI 87
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXXXXG 142
LVNNAG + + TS +D L N+R + T ++ + G G
Sbjct: 88 LVNNAGGTFSSPLLETSENAWDALYKANLRHVLLCTQRVAQQMVAAGVGGSVITVTSIEG 147
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+R+ PG AY +KA V +T+ A ELAP G+RVN + P V++TE GL
Sbjct: 148 VRAAPGYAAYAAAKAGVVNYTQTAAFELAPHGIRVNALAPDVVVTE-----GLVALSPGG 202
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHA 250
+ +GRPG DE+A FLASDLA ITG ++ VDGG HA
Sbjct: 203 LPAGIGDAIPMGRPGTVDEIAGAAVFLASDLAGYITGETLHVDGGTHA 250
>UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacillus|Rep: Short-chain dehydrogenase/reductase
SDR - Bacillus coagulans 36D1
Length = 260
Score = 115 bits (277), Expect = 1e-24
Identities = 67/197 (34%), Positives = 111/197 (56%), Gaps = 6/197 (3%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVR 114
+++ D+T ++ + KT+ + +LD++ +NAGI T IE+ + +++ ++TN++
Sbjct: 57 MALEVDVTDPEQVKTAVDKTVREWDRLDIVFSNAGINGTVAPIEDLTPDDWEKTLSTNLK 116
Query: 115 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP--GVLAYNISKASVDQFTRCVALELAP 172
+ LT A+PH+ G G R F G+ AY+ SKA F + ALELA
Sbjct: 117 GTFLLTKYAIPHMKNRGGSIIITSSINGNRIFSNIGMSAYSSSKAGQVAFMKMAALELAR 176
Query: 173 KGVRVNCVNPGVILTELQRRGGLSEE--QYAAFLERTKETHAL-GRPGKPDEVAATIAFL 229
+RVN V PG I T++++ +EE + +E + L GRPGKP+EVA + FL
Sbjct: 177 YKIRVNAVCPGAIETKIEQNTNRTEELEKVQIPIEFPEGDQPLSGRPGKPEEVADLVLFL 236
Query: 230 ASDLASNITGASVPVDG 246
ASD +S+I+G + +DG
Sbjct: 237 ASDDSSHISGTDIYIDG 253
>UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain
dehydrogenase/reductase SDR - Verminephrobacter eiseniae
(strain EF01-2)
Length = 265
Score = 115 bits (277), Expect = 1e-24
Identities = 74/246 (30%), Positives = 120/246 (48%), Gaps = 2/246 (0%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADL 62
AGKV + GAQ+ + + E Q + ++ A L + AD+
Sbjct: 14 AGKVALITGAGSGIGRATALLFATEGAQIVVCDLDPEGGQATVRAIEQAGAQALFVQADV 73
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ +D + +++T+ H+ +LDVL NNAGI + +TS A +D +M NV+SI+ ++
Sbjct: 74 AQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFLMSRQ 133
Query: 123 AVPHLLESKGXXXXXXXXX-GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
AVP + E G G+ ++Y +K +V TR +AL+ P+ +RVN V
Sbjct: 134 AVPVMAEQGGGSIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMALDHGPQRIRVNSVC 193
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG T + R L + L R G+ +E+A + FLASD +S +TG++
Sbjct: 194 PGDTDTAMLRDEARQLGLPETALVLAGNSRPLMRVGRAEEIAQVVLFLASDRSSFVTGSA 253
Query: 242 VPVDGG 247
VDGG
Sbjct: 254 YVVDGG 259
>UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13;
n=4; Bilateria|Rep: Dehydrogenases, short chain protein
13 - Caenorhabditis elegans
Length = 257
Score = 115 bits (277), Expect = 1e-24
Identities = 74/229 (32%), Positives = 122/229 (53%), Gaps = 7/229 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L GA + + R EN+ + V+ + TA + +SD K+I T+D + KLD
Sbjct: 31 LGAAGASVVVCSRKKENVDEAVAALRLENIDAHGTTAHVGNKSDRTKLIDFTLDRFTKLD 90
Query: 84 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 141
+LV+NA + G + + +Q+D+L++ NV+S + LT AVPHL S +G
Sbjct: 91 ILVSNAAVNPHYGDLMKVTDSQWDKLLDLNVKSAFELTKEAVPHLEASGRGNVVFVSSVA 150
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G + AY++ K ++ ++ +AL LA + +RVN + PG+I T+ + E +
Sbjct: 151 GYSPMNEIGAYSVMKTTLTGLSKSLALNLARRNIRVNSIAPGIIQTDFSQVLFSDESEKQ 210
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHA 250
+L + + R G PDE A +AFL SD AS I+G ++ ++GG HA
Sbjct: 211 KWLSQIAQR----RFGDPDECAEAVAFLVSDEASYISGETIGINGGMHA 255
>UniRef50_Q5FPE5 Cluster: NAD(P)-dependent glucose 1-dehydrogenase;
n=1; Gluconobacter oxydans|Rep: NAD(P)-dependent glucose
1-dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 266
Score = 115 bits (276), Expect = 1e-24
Identities = 79/249 (31%), Positives = 119/249 (47%), Gaps = 8/249 (3%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS--ITA 60
FAGK V ++ GAQ++L GR + L V + K + T
Sbjct: 9 FAGKKVLVTGASQGIGEATALRFAEEGAQVALNGRKEDKLIAVREKLPKVSGGEHPIATG 68
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D++KE D+++++ ++I G LDVLV NAG E+ L ++ +M NV +
Sbjct: 69 DISKEDDVKRLVAESIKAMGGLDVLVCNAGYQIPSPSEDIKLEDFEGVMAVNVTGVMLPC 128
Query: 121 MLAVPHLLES--KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
+ + LE+ KG I P L Y+ SK +V R +ALE A +G+RVN
Sbjct: 129 REVIRYWLENGIKGTIIVNSSVHQIIPKPHYLGYSASKGAVGNIVRTLALEYATRGIRVN 188
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
V PG I+T + EQY A + RPG+ E+A I FLA++ ++ IT
Sbjct: 189 AVAPGAIVTPINMSWIDDPEQYKAVSSHI----PMKRPGESREIADAITFLAAEDSTYIT 244
Query: 239 GASVPVDGG 247
G ++ VDGG
Sbjct: 245 GQTLYVDGG 253
>UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase family
oxidoreductase, putative; n=3; Pezizomycotina|Rep: Short
chain dehydrogenase/reductase family oxidoreductase,
putative - Aspergillus clavatus
Length = 249
Score = 115 bits (276), Expect = 1e-24
Identities = 66/193 (34%), Positives = 103/193 (53%), Gaps = 7/193 (3%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVR 114
+++ AD++K DI +++K T+D +GK+DVLV NAG++ + G + + + +D L NVR
Sbjct: 57 IAVQADVSKREDIARLVKTTVDRFGKIDVLVLNAGLLWQKGDLLSITEQDFDTLFAANVR 116
Query: 115 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF-PGVLAYNISKASVDQFTRCVALELAPK 173
S + A PHL E P L Y SK +V+Q TR +A +L +
Sbjct: 117 SPLFTIQEAAPHLTEGGRVMLFSTSLAAFSGVTPNYLLYAASKGAVEQMTRVLAKDLGRR 176
Query: 174 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 233
G+ VN + PG I T+ G + EQ T GR GKP+EVAA + F+ASD
Sbjct: 177 GITVNTIAPGPIGTDAYFVG--NNEQMVQLQSNLAPT---GRLGKPEEVAAVVNFIASDQ 231
Query: 234 ASNITGASVPVDG 246
+ + G ++ ++G
Sbjct: 232 SQWVNGQTIRING 244
>UniRef50_P66781 Cluster: Uncharacterized oxidoreductase
Rv1350/MT1393; n=19; Actinomycetales|Rep:
Uncharacterized oxidoreductase Rv1350/MT1393 -
Mycobacterium tuberculosis
Length = 247
Score = 115 bits (276), Expect = 1e-24
Identities = 69/221 (31%), Positives = 114/221 (51%), Gaps = 7/221 (3%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++ L N+E + +K L++ D+T+ D++ +I+ ++ +G LDV+VNN
Sbjct: 31 GARVVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGGLDVMVNN 90
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFP 147
AGI T+ + Q+D+++ +++ + T LA + E K G G
Sbjct: 91 AGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRGAIVNMSSVSGKVGMV 150
Query: 148 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 207
G Y+ +KA + T+ A ELA G+RVN + PG+I R ++E ++
Sbjct: 151 GQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPGLI------RSAMTEAMPQRIWDQK 204
Query: 208 KETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
+GR G+P EVA+ FLASDL+S +TG + V GGR
Sbjct: 205 LAEVPMGRAGEPSEVASVAVFLASDLSSYMTGTVLDVTGGR 245
>UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Marinomonas sp. MED121|Rep: Short-chain
dehydrogenase/reductase SDR - Marinomonas sp. MED121
Length = 255
Score = 114 bits (275), Expect = 2e-24
Identities = 72/254 (28%), Positives = 121/254 (47%), Gaps = 3/254 (1%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSIT 59
MNF +VV ++ GA+L+L NV L + + ++ S
Sbjct: 2 MNFKDQVVLITGASGGLGKEAAKQFAQQGAKLALCDLNVAALNDLGTELIEQGYEVFSQP 61
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYY 118
D++ E +++ I T H+G+LDV +NNAGI + T+ + ++R+M+ NV+ +Y
Sbjct: 62 CDVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYL 121
Query: 119 LTMLAVPHLLESKGXXX-XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
+PH+++ G GI P + AY SK +V T+ VA E G+RV
Sbjct: 122 CMKYQIPHMIKQGGGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVAHEYGRAGIRV 181
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
N V P + +T++ + + + L + + AL R +P+EVA + F S +
Sbjct: 182 NSVCPYITMTDMVEQHLKTLDNREEVLAKYSKASALRRVAQPNEVAKVMLFACDKNNSYM 241
Query: 238 TGASVPVDGGRHAM 251
TG + VDGG A+
Sbjct: 242 TGQELVVDGGMTAV 255
>UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales
bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales
bacterium HTCC2150
Length = 279
Score = 114 bits (275), Expect = 2e-24
Identities = 75/227 (33%), Positives = 120/227 (52%), Gaps = 8/227 (3%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA + + N E L + +D +F +S + D+TK +++ ++ + +YG LDV++N
Sbjct: 48 GANVVMADVNAEKLAESVQDLIEFDGAVSSMVCDVTKRENLQALVGLAVSNYGNLDVMIN 107
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESK-GXXXXXXXXXGIRS 145
NAGI + S +YD +M+ N+R + T +A ++ + K G + +
Sbjct: 108 NAGIAKVQDFLEISDDEYDAVMDVNLRGAFIGTQIAGKQMIAQGKGGVIINMSSINALVA 167
Query: 146 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL-SEEQYAAFL 204
P + Y ISK ++Q T A+ LAP +RV + PG ILT++ + S E L
Sbjct: 168 NPMLSTYAISKGGMNQLTNIAAVGLAPHNIRVCGIGPGTILTDMVADVIMTSPEARHNVL 227
Query: 205 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHAM 251
RT + R G+P E+A+ AFLASD AS +TG +V DGGR A+
Sbjct: 228 SRT----PMERCGEPREIASVAAFLASDDASYMTGQTVYPDGGRMAL 270
>UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase;
n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein
reductase - Leptospira interrogans
Length = 254
Score = 114 bits (274), Expect = 2e-24
Identities = 74/228 (32%), Positives = 118/228 (51%), Gaps = 12/228 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE---KIIKKTIDHYGK 81
L+K GA L + N E+ + + + K +I T SD++ K I+ +D +G
Sbjct: 26 LAKAGANLVIADLNEESSKATADEISKQTGVKAIGIG-TNVSDVDSAAKAIQACVDEFGS 84
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXX 139
+D+LVNNAGI + + Q+D ++ N+ + T A+ ++++ G
Sbjct: 85 VDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCTQAAIKFMMKNPNGGSIINLSS 144
Query: 140 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 199
G+ G Y+ SKA V FT+ VALE+A + VR N + PG I TE+ + E+
Sbjct: 145 IAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVRCNAIAPGFIATEM--TDAIPEKI 202
Query: 200 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
A + L R G+P+++A TIAFLASD++S ITG + V+GG
Sbjct: 203 RTAMVAAI----PLKRAGQPEDIANTIAFLASDISSFITGQVIEVNGG 246
>UniRef50_Q46PX5 Cluster: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR; n=2; Bacteria|Rep:
NAD-dependent epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR - Ralstonia eutropha (strain
JMP134) (Alcaligenes eutrophus)
Length = 253
Score = 114 bits (274), Expect = 2e-24
Identities = 66/190 (34%), Positives = 102/190 (53%), Gaps = 9/190 (4%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYL 119
D+++E D ++I T+ +G+LD++V NAGI + +E+ S+ Q+ ++++ N+ ++
Sbjct: 66 DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125
Query: 120 TMLAVPHLLE--SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
LA+ + + + G G PG +YN +K V TR + + A G+RV
Sbjct: 126 NKLAIVQMKKQGTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLGVSHAQDGIRV 185
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
N V PG + T L R +EE A R H +GR G DEVA + FLASD AS I
Sbjct: 186 NAVCPGFVATPLIERA--TEEARA----RLVAAHPIGRLGHADEVAKAVLFLASDDASFI 239
Query: 238 TGASVPVDGG 247
G S+ VDGG
Sbjct: 240 VGTSLMVDGG 249
>UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Bacillus sp. B14905
Length = 254
Score = 114 bits (274), Expect = 2e-24
Identities = 79/253 (31%), Positives = 119/253 (47%), Gaps = 6/253 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 59
M KV +K GA++ +T N ++ + D F L +
Sbjct: 4 MRLENKVAVITGGGTGIGKETALLFAKEGAKIVITDINEQSGNETVSDIQAFGGEALFVL 63
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D++ E D +K+ + I + K+D+L NNAGI + L+ ++RLM+ NV + +L
Sbjct: 64 HDVSNEDDWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGV-FL 122
Query: 120 TMLAVPHLL--ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
M + L+ ++KG G+ G + Y SK +V T+ A+E AP GVRV
Sbjct: 123 GMKHIMPLMAKQNKGSVINASSIAGLTGAAGHVLYGASKGAVRIMTKDAAMEYAPYGVRV 182
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
N ++PG I T + S ++ E K LGR G EVA T+ FLASD +S
Sbjct: 183 NSIHPGYIDTGMADYA--SATTGSSKDELGKNLFPLGRLGSVKEVAQTVLFLASDESSFS 240
Query: 238 TGASVPVDGGRHA 250
TGA +DGG A
Sbjct: 241 TGAEFVIDGGATA 253
>UniRef50_A0JC04 Cluster: (R)-2-octanol dehydrogenase; n=2;
Pichia|Rep: (R)-2-octanol dehydrogenase - Pichia
finlandica
Length = 254
Score = 114 bits (274), Expect = 2e-24
Identities = 69/193 (35%), Positives = 103/193 (53%), Gaps = 10/193 (5%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
+ AD +KE D +K+I +T+ +G LD++ NAGI + T + +++ N+ ++
Sbjct: 65 VQADSSKEEDNKKLISETLATFGGLDIVCANAGIGKFAPTHETPFDVWKKVIAVNLNGVF 124
Query: 118 YLTMLAVPHLLESKGXXXXXXXXXGIRSF---PGVLAYNISKASVDQFTRCVALELAPKG 174
L LA+ + LE K + SF PG+ Y +K V T+ +ALE A G
Sbjct: 125 LLDKLAINYWLE-KSKPGVIVNMGSVHSFVAAPGLAHYGAAKGGVKLLTQTLALEYASHG 183
Query: 175 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
+RVN VNPG I T L +E L++ H +GR G+P+EVA +AFL S A
Sbjct: 184 IRVNSVNPGYISTPL------IDEVPKERLDKLVSLHPIGRLGRPEEVADAVAFLCSQEA 237
Query: 235 SNITGASVPVDGG 247
+ I G S+PVDGG
Sbjct: 238 TFINGVSLPVDGG 250
>UniRef50_Q3KDE6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=7; Gammaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Pseudomonas fluorescens
(strain PfO-1)
Length = 254
Score = 113 bits (273), Expect = 3e-24
Identities = 71/245 (28%), Positives = 121/245 (49%), Gaps = 10/245 (4%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLT 63
AGKV L GAQ+ N E ++ +++ + + AD+T
Sbjct: 13 AGKVALVTGAASGIGKAIALLLHARGAQVIAEDINPE-VEALARP-----GLVPLVADIT 66
Query: 64 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLA 123
++ E+ + ++ +G+LD+LVNNAGII + + + ++R+ N + + + A
Sbjct: 67 QDGAAERAVALAVEQFGRLDILVNNAGIIINKLVIDMTREDWERIQAVNATAAFLHSREA 126
Query: 124 VPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
V ++ +K G +FP + AY SK ++ Q TR +ALE+ G+RVN V
Sbjct: 127 VKAMMPNKSGSIVNIASYASYFAFPTIAAYTASKGALAQLTRTLALEVIGHGIRVNAVGV 186
Query: 183 GVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASV 242
G ++T + + AFL + E +GR +P+E+A +AF+ASD AS + G+ V
Sbjct: 187 GDVVTNILNN---VVDDGPAFLAQHGEAAPIGRAAQPEEIAEVVAFIASDRASFMVGSVV 243
Query: 243 PVDGG 247
DGG
Sbjct: 244 MADGG 248
>UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Alteromonadales|Rep: Short-chain
dehydrogenase/reductase SDR - Shewanella denitrificans
(strain OS217 / ATCC BAA-1090 / DSM 15013)
Length = 246
Score = 113 bits (273), Expect = 3e-24
Identities = 64/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L D++ D+E + +G +D L+ NAGI + I + + A +D+ MN NV+
Sbjct: 52 LVFKGDVSVNKDLEDFFNTCYELWGGIDTLIANAGIAQPENIADVTEASFDKCMNINVKG 111
Query: 116 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLA-YNISKASVDQFTRCVALELAPKG 174
+++ ++ +L +K + G+ + Y +KA+V TR A L P+G
Sbjct: 112 VFFTVQKSLGYL--NKAASIIILSSIQAQRGAGIWSVYGATKAAVRSLTRSFAQALGPEG 169
Query: 175 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
+RVN ++PGV T + + G +E+Q A L + LGR P E+A + FLASD A
Sbjct: 170 IRVNTLSPGVTDTPILTKFGFAEDQLADILAQVSANTPLGRIASPAEIAKSALFLASDNA 229
Query: 235 SNITGASVPVDGG 247
S ITGA + VDGG
Sbjct: 230 SFITGADLQVDGG 242
>UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=3; Flavobacteriaceae|Rep:
3-oxoacyl-(Acyl-carrier protein) reductase -
Leeuwenhoekiella blandensis MED217
Length = 246
Score = 113 bits (273), Expect = 3e-24
Identities = 67/220 (30%), Positives = 116/220 (52%), Gaps = 6/220 (2%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
G ++ + GRN E ++ + + + + I DL I K+I + + GK+DVLVNN
Sbjct: 27 GYKVYIIGRNEEKTRQAADNLGELV--VPIVFDLNNLEAIPKLIDELLQATGKIDVLVNN 84
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR-SFP 147
AGI + A++DR+++TNV+S++ ++ V + + G + P
Sbjct: 85 AGINMKKDFAEVTDAEFDRILHTNVKSVFAISREVVKSMKGNYGGSIVNISSMAAQYGIP 144
Query: 148 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 207
V+AY SK +++ TR +A++LA +RVNCV PG I T + + S++Q +R
Sbjct: 145 QVIAYTASKTAIEGMTRAMAVDLAQYNIRVNCVAPGFIKTPMTAKALNSDKQRK---DRV 201
Query: 208 KETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+G+ G P+++A + +LA + ITG + VDGG
Sbjct: 202 FSRTPMGKMGAPEDIADAVFYLAGKESKFITGTVLCVDGG 241
>UniRef50_A0JTT9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=13; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Arthrobacter sp. (strain FB24)
Length = 297
Score = 113 bits (273), Expect = 3e-24
Identities = 71/188 (37%), Positives = 103/188 (54%), Gaps = 6/188 (3%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYL 119
DL + +++ + G LD+LVNNAG + IE S Q+D + TNV ++++L
Sbjct: 111 DLKDAAVCRELVDTAVRELGGLDILVNNAGKQVAQEDIEEISDEQFDHTLKTNVYAMFWL 170
Query: 120 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
T AVPHL + P ++ Y +KAS++ FT+ +A +LAPKG+RVN
Sbjct: 171 TKAAVPHL-PAGSTIINTTSIQAYNPSPTLVDYATTKASINNFTKGLAQQLAPKGIRVNA 229
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
V PG I T LQ G +E A E K+T LGR G+P E+A FLAS +S + G
Sbjct: 230 VAPGPIWTPLQVSSGQPKE---ALPEFGKDT-PLGRAGQPAELAPAYVFLASAESSYVVG 285
Query: 240 ASVPVDGG 247
++ V+GG
Sbjct: 286 ETLNVNGG 293
>UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9;
Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas
sp. (strain NCIMB 9872)
Length = 250
Score = 113 bits (273), Expect = 3e-24
Identities = 77/244 (31%), Positives = 121/244 (49%), Gaps = 6/244 (2%)
Query: 6 KVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFASTLSITADLTK 64
KVV L++ GA + L+ N E Q V++ + + D+T
Sbjct: 7 KVVLVTGGAMGMGLTHCTLLAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTN 66
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
E+ + + +LD LVNNAGI+ +++TS ++DR+ NVRS++ T +
Sbjct: 67 ENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVI 126
Query: 125 PHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 183
+ ++ KG G+ PG AY SK +V FT+ A++LAP +RVN V+PG
Sbjct: 127 EPMRKAHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRVNSVHPG 186
Query: 184 VILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVP 243
VI T + ++ + + A L T LGR +P EV+ + FL SD AS + G+ +
Sbjct: 187 VIATPMTQQILDAPQSARALLGPT----LLGRAAQPMEVSQAVLFLVSDEASFVHGSELV 242
Query: 244 VDGG 247
VDGG
Sbjct: 243 VDGG 246
>UniRef50_Q82KL5 Cluster: Putative dehydrogenase; n=1; Streptomyces
avermitilis|Rep: Putative dehydrogenase - Streptomyces
avermitilis
Length = 273
Score = 113 bits (272), Expect = 4e-24
Identities = 73/234 (31%), Positives = 122/234 (52%), Gaps = 14/234 (5%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
G + ++GR E L+++ ++ L+ +D+ + +++ + YG+LD LV N
Sbjct: 28 GHHVVISGRRAEPLRRLERE----TGALACPSDVGDPDAADGLVRTALAAYGRLDGLVLN 83
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 148
AGI G + + SL + +M TNV L A+PHLL++KG +R+
Sbjct: 84 AGIGRGGAVGDVSLEDWHDVMRTNVTGPLLLLRAAIPHLLDTKGAVVAVASVSALRNGAS 143
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL--QRRGGLSEEQ------- 199
+ Y SKA++ Q R VA++ +GVR N V P + +E+ +R +EE
Sbjct: 144 NVPYATSKAALLQLCRSVAVDYGRQGVRANIVCPSWVRSEMADRRMARFAEEADLKDGSV 203
Query: 200 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHAMCP 253
+A+ E T+ LGRPG+P E+A I++L S AS + G+ + +DGG A+ P
Sbjct: 204 ESAYEEATRFL-PLGRPGEPREIAEAISWLLSPAASYVNGSVLTLDGGATALDP 256
>UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Roseovarius sp. HTCC2601
Length = 255
Score = 113 bits (272), Expect = 4e-24
Identities = 65/194 (33%), Positives = 102/194 (52%), Gaps = 6/194 (3%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
+++ D++ E ++ + + I +G LD +VN AG+ G I +T +D MN N+
Sbjct: 58 VAVGVDVSDEDKVDAMTAEGIAKFGGLDGVVNCAGVRGVGNILDTDHGVWDLNMNVNIEG 117
Query: 116 IYYLTMLAVPHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 173
+ + + E G G+ + P L+Y SK V TR VA+E+AP
Sbjct: 118 SFNTSQAFCRYAREHNRPGSIVNISSQAGVEAVPNRLSYVTSKHGVVGLTRGVAIEMAPH 177
Query: 174 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 233
G+R N + PG+I T + E LE+ ++ H +GR G+P+E+AA I+FL SD
Sbjct: 178 GIRCNGIAPGMIATAMTAGMRADPEN----LEKIRKAHPIGREGQPEEIAAVISFLLSDD 233
Query: 234 ASNITGASVPVDGG 247
AS +TG +PVDGG
Sbjct: 234 ASYVTGIMMPVDGG 247
>UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family precursor; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family precursor - Syntrophomonas wolfei subsp. wolfei
(strain Goettingen)
Length = 252
Score = 113 bits (272), Expect = 4e-24
Identities = 76/249 (30%), Positives = 121/249 (48%), Gaps = 4/249 (1%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSIT 59
M GKV L+ GA++ + GR E L + V ++ L+I
Sbjct: 1 MKLKGKVAVITGGGTGIGRAAAIALAAEGARVVVMGRRPEPLNETVDIVKERGGEGLAIP 60
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
+D+TK DIEK + + YG+LD+LVNNAG TSL +DR+ ++RS++ +
Sbjct: 61 SDVTKIEDIEKARDEVRETYGRLDILVNNAGSALFKPFMKTSLEDFDRIYQVDLRSVFAV 120
Query: 120 TMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
+ L +P +LE G G+ AY K V Q TR +A EL P+ +RVN
Sbjct: 121 SQLMLPLMLEGGGGSIINIASILGVLGGKSSSAYCAMKGGVVQLTRALAAELGPE-IRVN 179
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
C+ P I+T + LS + +++ + + R P+++ +I F ASD + +T
Sbjct: 180 CLCPSHIITPMM-EDELSRIESKGKMDKLTKMFPMKRLAYPEDMTGSILFYASDDSKWLT 238
Query: 239 GASVPVDGG 247
G + +DGG
Sbjct: 239 GNILMIDGG 247
>UniRef50_P95719 Cluster: Ata4 protein; n=2; Actinomycetales|Rep:
Ata4 protein - Streptomyces capreolus
Length = 256
Score = 113 bits (272), Expect = 4e-24
Identities = 69/199 (34%), Positives = 101/199 (50%), Gaps = 6/199 (3%)
Query: 53 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 112
A + + DL +E +++ ++ +G+LDVLV NAG + S +DR N
Sbjct: 63 ARAVPVQGDLAREKACVAAVERVVESFGRLDVLVANAGRHRDALLLRLSEDDWDRHQEAN 122
Query: 113 VRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
++S Y A+P +L + G G+ PG AY+ +KA + R VA E
Sbjct: 123 LKSAYLCVRAALPSMLRQRHGRIVLVSSVAGLVGSPGQAAYSAAKAGLAGLARTVAHEHG 182
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
GV NCV PG+I + GLSE + L+RT A R G+P+EVAA +AFL+S
Sbjct: 183 RYGVTCNCVAPGLI-ADTPSHDGLSEARRRQILDRT----AAQRAGRPEEVAAAVAFLSS 237
Query: 232 DLASNITGASVPVDGGRHA 250
A+ +TG + VDGG A
Sbjct: 238 PAAAYVTGQVLAVDGGMTA 256
>UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Sphingomonas wittichii RW1
Length = 266
Score = 113 bits (272), Expect = 4e-24
Identities = 72/225 (32%), Positives = 109/225 (48%), Gaps = 6/225 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L+ GA L L R+ L +V+ + K +T DL + +E + +D +D
Sbjct: 29 LADAGASLILAARDAAKLGEVADEVRAKGRDARIVTFDLADMASVEAAARGLVDEGAPID 88
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM-LAVPHLLESKGXXXXXXXXXG 142
+LVNN GI E G + +SL ++R + NV +IY L L+ P G
Sbjct: 89 ILVNNGGIAEWGPLHGSSLDHWERTFDVNVSAIYLLCRELSKPMAERGWGRIINFASYVA 148
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
P + AY SK +V TR VA +LAP GV N + PG+ LT++ ++
Sbjct: 149 ETGRPNLSAYVASKHAVLGLTRAVAADLAPHGVTCNAIAPGIFLTDMAAPTAGHPQRAKI 208
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
F ++ A+GR G P E+ + FLAS+ + +TG +PVDGG
Sbjct: 209 F----RDAIAIGRFGDPAEIVGPVQFLASEASRYVTGHMLPVDGG 249
>UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family protein; n=3;
Bacteroidetes|Rep: Oxidoreductase, short-chain
dehydrogenase/reductase family protein - Polaribacter
dokdonensis MED152
Length = 257
Score = 113 bits (272), Expect = 4e-24
Identities = 72/249 (28%), Positives = 122/249 (48%), Gaps = 7/249 (2%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITA 60
N +GKV L++ GAQ+ ++ RN E +V+K+ ++ T+ I
Sbjct: 8 NLSGKVAVITGSSKGIGKAIAKGLAEQGAQVVISSRNQEACDEVAKEFKEQGLDTIGIAC 67
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYL 119
+ KE + ++ KTI+ +G++D+LVNNA I G IE S +D++M+ NV++ + L
Sbjct: 68 HIGKEDQRKNLVDKTIESFGRIDILVNNAAINPVFGPIEEVSPEIFDKIMDVNVKAPWSL 127
Query: 120 TMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
+ L +PH +K G + G+ Y+ SKA++ T+ A E GV+ N
Sbjct: 128 SNLVLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTKNQAKEWGKYGVKAN 187
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
+ PG+I T+ +E+ L + ++ R G P+E+ LASD + +T
Sbjct: 188 AICPGLIKTKFSAALWQNEK----ILSKVEKALPSSRMGMPEEMVGLACLLASDAGNYMT 243
Query: 239 GASVPVDGG 247
G DGG
Sbjct: 244 GGVYTADGG 252
>UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Candidatus Desulfococcus oleovorans
Hxd3|Rep: Short-chain dehydrogenase/reductase SDR
precursor - Candidatus Desulfococcus oleovorans Hxd3
Length = 266
Score = 113 bits (272), Expect = 4e-24
Identities = 70/226 (30%), Positives = 119/226 (52%), Gaps = 8/226 (3%)
Query: 29 GAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA +++ R +ENL V+++ K L + A + + + I+++ + +G++D+LVN
Sbjct: 35 GADVAIVSRKMENLAPVAEEIKAKGKRCLPVAAHVGRMDQLPAIVEQVVAEFGQIDILVN 94
Query: 88 NAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 146
NA TI +D ++ N++ +Y+L+ AV ++E KG I F
Sbjct: 95 NAATSPAYATIFEAQEKLWDSIIGLNLKGLYFLSQ-AVARVMEEKGAGGSIINVSSIDGF 153
Query: 147 PG---VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR--GGLSEEQYA 201
V Y+ISKA V+ TR +ALELAP +RVN + PG T+L L E++
Sbjct: 154 APQAQVGIYSISKAGVNMATRSMALELAPHKIRVNAIAPGATRTKLFEGLFAFLPEDERE 213
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+++ + LGR PD++ + +LASD ++ +TG V V+GG
Sbjct: 214 KQIQQIGQAFPLGRVAVPDDMVGLMLYLASDASAYMTGQVVAVEGG 259
>UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=2; Bacillus|Rep: 3-oxoacyl-(Acyl-carrier
protein) reductase - Bacillus halodurans
Length = 252
Score = 113 bits (271), Expect = 5e-24
Identities = 67/220 (30%), Positives = 113/220 (51%), Gaps = 3/220 (1%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++++ R+ LQ+ + + + L+I AD+T +++ EK+ + ++ YG +D+LVNN
Sbjct: 31 GAKVAIVARDAHGLQEAKR---QLGNVLTIQADVTDKNEREKVFSQLLETYGTIDILVNN 87
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 148
AG G I T L+ ++ + N S + + LA+P + + R G
Sbjct: 88 AGGSNGGLISETELSLFEEAFSLNYFSAVHFSQLALPVMKAKQSGAIINISSIFGRESGG 147
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 208
YN +KA++ FT+ +A E+ G+RVN + PG IL EE +
Sbjct: 148 KATYNSAKAAMISFTKSLADEVIRDGIRVNGIAPGSILHPTGNWQKRLEENREKMEQFID 207
Query: 209 ETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
+ GR G +E+A FLAS+ AS + GA++ VDGG+
Sbjct: 208 QNIPAGRFGTVEEIANVAVFLASEKASWVVGATLNVDGGQ 247
>UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 254
Score = 113 bits (271), Expect = 5e-24
Identities = 76/251 (30%), Positives = 119/251 (47%), Gaps = 5/251 (1%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLT 63
GKVV L GA+++L N ++L K + + +IT ++T
Sbjct: 3 GKVVLITGGAGGIGQATAKLLLDYGAKVALVDINEDSLVKAKESLHVEDDRVFTITGNVT 62
Query: 64 KESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYY-LTM 121
E D+E +K+T+D +GK+DV NNAG+ I A ++++M+ NV ++ L
Sbjct: 63 VEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLKH 122
Query: 122 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
+ + G G+++Y SK +V T+ ALE+A G+RVN V
Sbjct: 123 VMKQMKKQGYGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAALEVASDGIRVNAVA 182
Query: 182 PGVILTEL--QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
P I T++ + L+ + E K+ GR G P+EVA + FLASD AS + G
Sbjct: 183 PAAIDTQMLADIQNNLTPGEPEKSGEALKQGIPAGRFGAPEEVAQVVKFLASDDASFVNG 242
Query: 240 ASVPVDGGRHA 250
+ VDGG A
Sbjct: 243 SLYNVDGGMQA 253
>UniRef50_Q9JN17 Cluster: Yhg; n=6; Rhizobiaceae|Rep: Yhg -
Agrobacterium tumefaciens
Length = 258
Score = 113 bits (271), Expect = 5e-24
Identities = 79/246 (32%), Positives = 118/246 (47%), Gaps = 8/246 (3%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV + GA+L L+ R E + ADL
Sbjct: 14 GKVALITGGTRGIGLATAYAFGEAGAKLYLSARR-EEYEDAGAILTAGYDVTFYPADLKT 72
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
++K+ D G+LD+L+NNAGI G + Q+ ++ TNV ++++ + A+
Sbjct: 73 REAACALVKRVADDAGRLDILINNAGIANGGDTPLFTEQQWRDVIATNVETVFWCSQAAI 132
Query: 125 PHLLE-SKGXXXXXXXXXGIRS-FP-GVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
P + E +G GI S P +AYN SKA+V T+ +A ELA +RVN V
Sbjct: 133 PVMREGGRGAIVNVGSMSGIVSNIPQNQVAYNSSKAAVHMMTKSLASELALDNIRVNAVA 192
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG I T++ R G + + +LE T + R G+PDE+A I FLAS+ +S +TG
Sbjct: 193 PGYIDTDMSRGGMVHPVRGPIWLEMT----PMKRFGRPDEIATAILFLASEASSYVTGDI 248
Query: 242 VPVDGG 247
+ VDGG
Sbjct: 249 LVVDGG 254
>UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1;
Terrabacter sp. DBF63|Rep: Short-chain
dehydrogenase/redutase - Terrabacter sp. DBF63
Length = 252
Score = 113 bits (271), Expect = 5e-24
Identities = 63/192 (32%), Positives = 101/192 (52%), Gaps = 5/192 (2%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSI 116
+ AD+T + ++ +++ +D YG+LD+ NNAGI TG + + ++ Q+D+++ N+ +
Sbjct: 60 VRADVTDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLTGV 119
Query: 117 YYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 175
+ +P +L + G G + AY SK V TR A+E + KG+
Sbjct: 120 FISMKAEIPQMLAQGGGSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAAVEYSDKGI 179
Query: 176 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
RVN V PGVI T + EE Y F + H +GR G P ++A +A+L SD A+
Sbjct: 180 RVNAVLPGVIQTPMI---DALEETYPGFKDALLTKHPIGRLGTPHDIAEMVAWLGSDAAA 236
Query: 236 NITGASVPVDGG 247
TG+ VDGG
Sbjct: 237 FATGSQFAVDGG 248
>UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Ralstonia metallidurans CH34|Rep: Short-chain
dehydrogenase/reductase SDR - Ralstonia metallidurans
(strain CH34 / ATCC 43123 / DSM 2839)
Length = 269
Score = 113 bits (271), Expect = 5e-24
Identities = 72/231 (31%), Positives = 127/231 (54%), Gaps = 12/231 (5%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
++LGA++ + R+ + + + + + + D+ +E++I ++ + +H+G +DV
Sbjct: 36 ARLGARVCVVDRDAASAAETTALIRAEGGAAETFVGDVAEEAEIARLFAEAREHFGPIDV 95
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGI 143
L +N GI +TG + +T + +D N NVRS+ + +P ++E +G G+
Sbjct: 96 LHHNVGIGKTGGVLDTDVRDFDAAHNVNVRSLLLASQQVLPSMVERGRGAIVTVSSVAGL 155
Query: 144 R--SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
R +P L+Y++SKA++ QFTR +A + A G+R NCV PG+I + R +Q++
Sbjct: 156 RYIGYPH-LSYSVSKAALIQFTRMIAQQYAGSGIRANCVVPGLI--DTPRIAHTVAKQFS 212
Query: 202 A-FLERTKETHA----LGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
A L+ + A + R G +VA AFLASD A+ ITG + VDGG
Sbjct: 213 ADSLDDARAARARQVPMQRMGTAWDVAHACAFLASDAAAYITGTELVVDGG 263
>UniRef50_A5UQR1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Roseiflexus|Rep: Short-chain
dehydrogenase/reductase SDR - Roseiflexus sp. RS-1
Length = 264
Score = 113 bits (271), Expect = 5e-24
Identities = 67/192 (34%), Positives = 107/192 (55%), Gaps = 11/192 (5%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
++I DL++ +D E+++ T++ +G+LD+LVNNAGI + + + + ++D L+NTN+RS
Sbjct: 80 IAIPGDLSRVADCERVVDATLEQWGRLDLLVNNAGIWGSTPVGSVTEERWDELLNTNLRS 139
Query: 116 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 175
++++ A L S G R + Y ISK V TR +A +LAP+ +
Sbjct: 140 MFFVAQRAADALRASHGVIINIADVGVERPWRNHTPYLISKGGVVTLTRALAKDLAPE-I 198
Query: 176 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
RVN + PG +L L ++ A ER T L R G P+++A + FLA A
Sbjct: 199 RVNAIAPGPVL--------LPDDWGAEQAERVARTTLLRRIGSPEDIADAVIFLAQ--AG 248
Query: 236 NITGASVPVDGG 247
ITG ++PVDGG
Sbjct: 249 YITGVTLPVDGG 260
>UniRef50_A4XFC0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Novosphingobium aromaticivorans DSM 12444|Rep:
Short-chain dehydrogenase/reductase SDR -
Novosphingobium aromaticivorans (strain DSM 12444)
Length = 246
Score = 113 bits (271), Expect = 5e-24
Identities = 75/251 (29%), Positives = 122/251 (48%), Gaps = 7/251 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
M F GK V + GA++++ +NV L++ + AS I
Sbjct: 1 MLFEGKNVIVTGAASGIGRATAIRFAAEGARVTIGDKNVAGLEETAA---MMASAPVIQP 57
Query: 61 -DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D + K+++ + LDVL N +G+++ G E+ SL +D +M N S++ L
Sbjct: 58 FDAVDNASCRKLVE--VGARNGLDVLCNISGVLKWGRSEDFSLEDFDLVMRVNTHSVFTL 115
Query: 120 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
A+PHL+ESKG ++ +AY SK +V T+ +A+E A +GVRVN
Sbjct: 116 CQAALPHLVESKGNIVNTASAAALQGIAYTVAYVASKHAVAGMTKSLAVEFASRGVRVNA 175
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
+ PG + T + ++ + E A + R L +P+++A AFLAS+ A ITG
Sbjct: 176 ICPGDVKTPMTQQTAVPENVDWALVMR-NAPKLLDGSCEPEDIAELFAFLASERARKITG 234
Query: 240 ASVPVDGGRHA 250
A +DGG+ A
Sbjct: 235 ALFSIDGGQLA 245
>UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Mycobacterium sp. (strain JLS)
Length = 255
Score = 113 bits (271), Expect = 5e-24
Identities = 73/227 (32%), Positives = 121/227 (53%), Gaps = 10/227 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA ++++GR+ E KV ++ L ITAD+T++ D++++ + I G LD
Sbjct: 31 LAQAGATVAISGRSAERNAKVVEEAAAEGFALHPITADITRQDDVDRMTAEAISALGHLD 90
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXG 142
+LVNNAG + + Q+D + + NV++++ ++ A H+ E G G
Sbjct: 91 ILVNNAGTCYHAESWDVTEEQWDSVFDLNVKALWACSLAAGAHMRERGSGSIVNIGSMSG 150
Query: 143 -IRSFPGVL-AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 200
I + P + AYN SKA+V T+ +A E P G+RVN + PG TE ++
Sbjct: 151 LIVNRPQMQPAYNASKAAVHHLTKSLAAEWGPLGIRVNALAPGYCKTE------MAPVDK 204
Query: 201 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
F + + + R P+E+A ++ FLASD AS ITG+ + DGG
Sbjct: 205 PEFKQHWIDDTPMLRYAMPEEIAPSVVFLASDAASFITGSVLVADGG 251
>UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reductase;
n=3; Trichocomaceae|Rep: 3-ketoacyl-acyl carrier protein
reductase - Aspergillus fumigatus (Sartorya fumigata)
Length = 256
Score = 113 bits (271), Expect = 5e-24
Identities = 77/259 (29%), Positives = 120/259 (46%), Gaps = 15/259 (5%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS------ 54
M+ GK+ L+K GA L+L + + Q +++ CD+ S
Sbjct: 1 MSLRGKIAIVTGASRGIGAGIALDLAKQGANLTLIYTSASSDQAINQLCDQIHSLNNGST 60
Query: 55 TLSITADLTKESDIEKIIKKTIDHY----GKLDVLVNNAGIIETGTIENTSLAQYDRLMN 110
+ + ADL +I+ T D + K+D+LVNNAG+ + +T+ + +
Sbjct: 61 AIKVQADLRHSDAPAQILAATFDAFPNANNKIDILVNNAGVSLCKNLADTTDHDISSVFD 120
Query: 111 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL 170
NV + +T +PHL + G R PG Y+ SKA+V+ FTR +A EL
Sbjct: 121 INVYGLISMTRAVIPHL-RAPGRIINLSSVAARRGSPGFSVYSASKAAVEGFTRSLACEL 179
Query: 171 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 230
P G VN V PG + +++ RR + E+ A E T H R P++ A + FLA
Sbjct: 180 GPVGCTVNAVQPGAVESDMLRR-EVPEQLIAYIQENTPLGH---RIALPEDTARVVTFLA 235
Query: 231 SDLASNITGASVPVDGGRH 249
+ A +TG S+ V GG H
Sbjct: 236 GEGAGWVTGQSICVSGGLH 254
>UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=4; Bacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 245
Score = 112 bits (270), Expect = 7e-24
Identities = 77/227 (33%), Positives = 117/227 (51%), Gaps = 13/227 (5%)
Query: 25 LSKLGAQLSLT-GRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKL 82
L+K GA + + R+ E +V + ++ T ++I AD++ ++ ++ KT++ YG++
Sbjct: 24 LAKEGATVVVNYARSAEAALEVVQRIEQQGGTAIAIAADVSVPEQVDTLVAKTVETYGRV 83
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 141
DVLVNNAGI + SL + ++N N+ ++ T +L+ K G
Sbjct: 84 DVLVNNAGITRDTLLLRMSLEDWQAVINLNLTGVFLCTRAVSKLMLKQKRGRIINIASVA 143
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G PG Y+ +KA V F++ VA ELA +G+ VN V PG I TE+ L E
Sbjct: 144 GQMGNPGQANYSAAKAGVIGFSKTVAKELASRGITVNAVAPGFIATEMTAE--LKAEDIL 201
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASD-LASNITGASVPVDGG 247
F+ LGR G+P EVA + FLA D A+ ITG VDGG
Sbjct: 202 KFI-------PLGRYGEPTEVAGMVRFLALDPAAAYITGQVFNVDGG 241
>UniRef50_Q89PN1 Cluster: Blr3449 protein; n=2; Bradyrhizobium|Rep:
Blr3449 protein - Bradyrhizobium japonicum
Length = 256
Score = 112 bits (270), Expect = 7e-24
Identities = 67/221 (30%), Positives = 114/221 (51%), Gaps = 6/221 (2%)
Query: 29 GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA++ +T + V+++ D + + D+T ++ ++ + G DV+VN
Sbjct: 37 GARVVVTDLGQDRADSVAREIRDGGKEAIGCSLDVTDALACGEVARRVDEELGLADVVVN 96
Query: 88 NAGIIETGTIENTSLAQ-YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 146
NAGII I++ + + ++ + NV + + +P L +S G S
Sbjct: 97 NAGIIIREPIDSPRAHENWRQVFDVNVNGTFNVVHAFIPALRKSPGTIINVASVAAFGSM 156
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 206
G + Y+ SK +V FT+ +A +LAP G+RVN V PG+I TE+ + + + + R
Sbjct: 157 GGTVGYSSSKGAVRLFTQALARDLAPDGIRVNAVAPGIIATEMSESTRGNPARLSGLMAR 216
Query: 207 TKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
T L R G+P+E+AA + FLAS +AS + G +PVDGG
Sbjct: 217 T----PLKRVGQPEEIAAPVIFLASAMASYVNGVILPVDGG 253
>UniRef50_Q7CHM2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=8; Yersinia|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Yersinia pestis
Length = 248
Score = 112 bits (270), Expect = 7e-24
Identities = 72/226 (31%), Positives = 113/226 (50%), Gaps = 8/226 (3%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
S++G + +GR E + + D + L + AD+ ESDI+ +I+ T++ +G LDV
Sbjct: 23 SEMGYNVVFSGRRPEEGRVILDDLKRINKDVLYVNADMNSESDIKHLIEMTLERFGSLDV 82
Query: 85 LVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXG 142
VN AG + ET I+ + + + NTNV +P ++E KG G
Sbjct: 83 AVNCAGTVGETAEIQAVTQDNFHLVFNTNVLGTLLAMKYQIPVMVERGKGSIINISSIAG 142
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL-QRRGGLSEEQYA 201
+ P Y SK +++ T+ ALE+A GVR+N ++PG + ++ R G E
Sbjct: 143 LVGLPSTGIYVASKHAIEGLTKTAALEVATTGVRINSISPGPVEGKMFDRFLGHDENNKK 202
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
AF+E R +EVA TI FLA D + ITG ++ +DGG
Sbjct: 203 AFIEMMPNK----RFTTQEEVAHTIVFLAEDNVTAITGQTITIDGG 244
>UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=225; cellular organisms|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio
cholerae
Length = 244
Score = 112 bits (270), Expect = 7e-24
Identities = 75/250 (30%), Positives = 122/250 (48%), Gaps = 9/250 (3%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
MN GKV L++ GA++ T + Q +S +++
Sbjct: 1 MNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMAL-- 58
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
++T IE ++K D +G +D+LVNNAGI + ++ +M TN+ SI+ L+
Sbjct: 59 NVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLS 118
Query: 121 MLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+ +++ + G G G Y +KA V FT+ +A E+A +GV VN
Sbjct: 119 KAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNT 178
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
V PG I T++ + L++EQ A L + GR G P E+A+ +AFLAS A+ ITG
Sbjct: 179 VAPGFIETDMTK--ALNDEQRTATLAQV----PAGRLGDPREIASAVAFLASPEAAYITG 232
Query: 240 ASVPVDGGRH 249
++ V+GG +
Sbjct: 233 ETLHVNGGMY 242
>UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=6; Burkholderiales|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 249
Score = 112 bits (269), Expect = 9e-24
Identities = 66/250 (26%), Positives = 116/250 (46%), Gaps = 5/250 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSIT 59
+ GKV L++ GA + +T N E Q +K D+ + I
Sbjct: 3 LGLTGKVAIVTGSARGLGAATARRLAQEGASVVITDINAELAQATAKALQDEGLAAHCIV 62
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+T+E+D+++++ +T+ H+G + +LVNNAG + S +D +MN ++ +
Sbjct: 63 GDITQEADVQRLVDETVAHFGGVHILVNNAGAPRDKYLVKMSADDWDFVMNVMLKGAFLA 122
Query: 120 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+PH +E P Y+ +KA + + +++E G+ NC
Sbjct: 123 ARAVMPHFIEQGWGRLINISSRAHLGNPTQANYSAAKAGLIGMAKALSMEEGRYGITANC 182
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
V PG + TE+ + + Y ER + R G+PD++A +AFLAS+ A I+G
Sbjct: 183 VAPGFMETEMVQ----ALPTYETIKERAVAAQPIKRVGRPDDIADAVAFLASERAGFISG 238
Query: 240 ASVPVDGGRH 249
+ V GGR+
Sbjct: 239 EVLHVTGGRY 248
>UniRef50_Q6JHM5 Cluster: Putative oxidoreductase, short chain
dehydrogenase; n=1; Saccharopolyspora spinosa|Rep:
Putative oxidoreductase, short chain dehydrogenase -
Saccharopolyspora spinosa
Length = 240
Score = 112 bits (269), Expect = 9e-24
Identities = 65/194 (33%), Positives = 95/194 (48%), Gaps = 1/194 (0%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
I D+ + ++ + + G LD +VN AGI +G +E +D + NV+S +
Sbjct: 47 IKCDVADSGSVAAMVDEAVTGLGGLDAVVNVAGIQRSGAVEVLDETDWDDQLRVNVKSCF 106
Query: 118 YLTMLAVPHLLESKGXXXXXXXX-XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
+ AVPHL + G G++ F G+ AY+ SK +V FTR +A+E+A +R
Sbjct: 107 LTSKYAVPHLRAAGGGSITTTASLAGLKGFAGMTAYSASKGAVIAFTRTLAVEVAADNIR 166
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
NC+ PG + T E A L K L R P E+A AFL SD AS
Sbjct: 167 ANCLCPGWVDTPFNDPVITFEGGREAHLANVKANVPLSREAAPPELAKWHAFLVSDAASY 226
Query: 237 ITGASVPVDGGRHA 250
+TG ++ VDGG A
Sbjct: 227 MTGQAITVDGGLSA 240
>UniRef50_A7NL33 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Roseiflexus castenholzii DSM 13941|Rep: Short-chain
dehydrogenase/reductase SDR - Roseiflexus castenholzii
DSM 13941
Length = 260
Score = 112 bits (269), Expect = 9e-24
Identities = 68/223 (30%), Positives = 108/223 (48%), Gaps = 2/223 (0%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 85
++ G + + N++ L K + + D + L+I D+ + I++T+ HYGK+D +
Sbjct: 28 ARAGGSVVIADINLD-LAKATLERDLQGNGLAIQCDVASSESVRAAIEQTLAHYGKIDAI 86
Query: 86 VNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 144
NNA I + + TS Q+D LM TN++S+YY T + L S+G G+
Sbjct: 87 HNNAAISRPSAPLHETSEEQWDALMATNLKSVYYTTFYGIDALKASRGCILNTASMVGVL 146
Query: 145 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 204
AY +K ++ T+ +AL+ A G+RVN + P + T L + AA
Sbjct: 147 GQERHAAYVATKGAMIALTKAMALDYASYGIRVNAICPAAVWTPLLHEWVQDQPDPAAAR 206
Query: 205 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ H LG D VA FL S+ A ITG ++PV GG
Sbjct: 207 QFLDGIHVLGYCPDGDVVADAAVFLLSERARFITGVALPVSGG 249
>UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Congregibacter litoralis KT71|Rep: Short-chain
dehydrogenase/reductase SDR - Congregibacter litoralis
KT71
Length = 259
Score = 112 bits (269), Expect = 9e-24
Identities = 71/226 (31%), Positives = 110/226 (48%), Gaps = 3/226 (1%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 83
++ GA L LT N + ++ + + + ++ D+T+ D E+ + +D +G LD
Sbjct: 30 MAAAGASLVLTDINHSAVAALADELGREGTQAAALQHDVTQPGDWERAVALAVDTFGGLD 89
Query: 84 VLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXX 141
+LVNNAGI T + N L + +++ N+ ++ + P L G
Sbjct: 90 ILVNNAGIAGDNTDLMNLDLENWHSVLSVNLDGVFLGLRYSGPALERRGGGSVINISSIL 149
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G FPG Y SK +V ++ ALE AP +RVN V+PG + T L R E A
Sbjct: 150 GKVGFPGAAPYCASKGAVTLLSKSAALEWAPLKIRVNSVHPGFVETPLVRDALAEREDGA 209
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E H +GR G E+A + FLASD AS +TG+ + +DGG
Sbjct: 210 EMAELLVAAHPIGRLGLATEIANAVTFLASDEASFMTGSELVIDGG 255
>UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Marinobacter sp. ELB17
Length = 264
Score = 112 bits (269), Expect = 9e-24
Identities = 78/231 (33%), Positives = 115/231 (49%), Gaps = 14/231 (6%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GAQ+ + + L + + A L D+ E+ +++++ +D +GK+D+L N
Sbjct: 30 GAQVIMADTSELGLAETGNLMPEGAEYLRRLVDVADEAQVKELVSDAMDAFGKIDILCNI 89
Query: 89 AGIIETG-----TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 142
AGI TG IEN ++D++++ N+ L PH+ K G G
Sbjct: 90 AGIASTGKGHPPVIENER-DEWDKVLSVNLIGTMLLIKHVAPHMQARKLGSIVNTASIAG 148
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
IRS G AY+ SKA V T A +L +RVN V PG++ T + R + YA
Sbjct: 149 IRSGAGGNAYSASKAGVINLTMTAACDLGDHNIRVNAVCPGLVETGMTR----AVFDYAR 204
Query: 203 FLERTKETHA---LGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHA 250
E+ + A L R G P+E+AA I F ASD AS ITG ++PVDGG A
Sbjct: 205 THEKAHKLGARCELRRYGDPEEIAAAILFFASDDASYITGQALPVDGGNTA 255
>UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Nocardioides sp. (strain BAA-499 / JS614)
Length = 253
Score = 112 bits (269), Expect = 9e-24
Identities = 68/252 (26%), Positives = 121/252 (48%), Gaps = 6/252 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
++F GKVV ++ GA++ + + + V + + L +
Sbjct: 5 LDFTGKVVLITGGATGIGRATALAFAQQGARVVVGDVDDRAAETVRLIEESGGTALFVRT 64
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+T +D++++++ T+D YG L V NNAGI+ TG + S +DR + +++ ++
Sbjct: 65 DVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPTGPLAEQSEDDFDRTIAVDLKGVFLA 124
Query: 120 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
+ H+ + G G+ + PG+ Y +K V TR A++ A GVRVN
Sbjct: 125 LKYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAAIDYAAAGVRVN 184
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
+ PG++ T + + ++ A + ++ R P+E+A T+ FLASDLAS T
Sbjct: 185 ALAPGLVDTPMTK----VWQEDAEIWDAVAASNGFHRAAAPEEIAGTVLFLASDLASFTT 240
Query: 239 GASVPVDGGRHA 250
G V D G+ A
Sbjct: 241 GTVVTADAGQTA 252
>UniRef50_A0J1E4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain
dehydrogenase/reductase SDR - Shewanella woodyi ATCC
51908
Length = 251
Score = 112 bits (269), Expect = 9e-24
Identities = 76/249 (30%), Positives = 122/249 (48%), Gaps = 6/249 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLT 63
AGK + + S +GA++ LTGRN E L + KD ++ L ADL
Sbjct: 6 AGKTILVTGASSGLGKAIAIYFSTVGARVVLTGRNEERLHETLKDMSG-SNHLYFIADLA 64
Query: 64 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT-ML 122
K + ++ + G LD +++ AGI +T ++ +D + NTNV+S ++ L
Sbjct: 65 KVESTQAMMDTVFANVGALDSVIHCAGIQKTLPLQALKEHHFDDIFNTNVKSAQFIAKFL 124
Query: 123 AVPHLLESKGXXXXXXXX-XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
S+G + P + +Y+ SKA++ ++ +A+ELA + +RVNC+
Sbjct: 125 RKKGRYNSQGTSLVLLSSVAAVCGEPAISSYSASKAALLGLSKSLAIELARQNIRVNCIA 184
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG + TE+ S++ A E H LG GKP+ +A FLASD + ITG +
Sbjct: 185 PGHVGTEMAIE--FSKQLTAEQRENILLKHPLGL-GKPEYIAQAAEFLASDKSCWITGTT 241
Query: 242 VPVDGGRHA 250
+ VDGG A
Sbjct: 242 IFVDGGYSA 250
>UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma
proteobacterium HTCC2207|Rep: Putative dehydrogenase -
gamma proteobacterium HTCC2207
Length = 259
Score = 111 bits (268), Expect = 1e-23
Identities = 63/176 (35%), Positives = 97/176 (55%), Gaps = 7/176 (3%)
Query: 78 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-----G 132
H+ LD++VN AG+ GTIE L +D+ M N+RS + A+ + + G
Sbjct: 79 HFSGLDIMVNVAGVTLMGTIEELDLETWDKTMAINLRSCFLGCQGAIKLMKSNSAESHGG 138
Query: 133 XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG--VRVNCVNPGVILTELQ 190
+++ P ++AYN SKA VD T+ VAL A G + VN +NPGVI T++
Sbjct: 139 SIINMASVSAVKAKPELVAYNASKAGVDMMTKSVALHCAVSGYGINVNSINPGVIETDML 198
Query: 191 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDG 246
++ E A ++ + H +GR G+P++VAA +LASD AS +TG++ VDG
Sbjct: 199 KKVMSQVEDGDALMDSYRALHPIGRIGQPEDVAAMAVYLASDDASFVTGSAFTVDG 254
>UniRef50_A3ZX88 Cluster: Putative dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep: Putative
dehydrogenase - Blastopirellula marina DSM 3645
Length = 251
Score = 111 bits (268), Expect = 1e-23
Identities = 72/224 (32%), Positives = 112/224 (50%), Gaps = 5/224 (2%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GAQ+ L RN E L + + +S ADL+ E++ + + ++DVLVN
Sbjct: 24 GAQVWLVARNAEKLATAADSLQSAGTKVMSTVADLSDPGAAEQVGVEVAATWDRVDVLVN 83
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 147
NAG+ + + + + N+ S Y LT +P L ++G R P
Sbjct: 84 NAGMARFTSFSEATPDEIQAQVQLNLLSPYLLTQQLLPLLAAAQGNVINISSTSAHRLIP 143
Query: 148 GVLA--YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR--GGLSEEQYAAF 203
G A Y ++K ++ T+ +ALEL P+GVRVN + PG I T L ++ +EE+ +
Sbjct: 144 GRPASVYAMTKGGLNSLTKALALELGPQGVRVNAIAPGTIKTPLTQKMIASFTEERKKEY 203
Query: 204 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ ++ ALGR G+P+EVA +LAS A TG+ VDGG
Sbjct: 204 DQFVRQAFALGRLGEPEEVAHLAVYLASVEAKWTTGSIFIVDGG 247
>UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=3; Planctomycetaceae|Rep:
3-oxoacyl-(Acyl-carrier protein) reductase -
Blastopirellula marina DSM 3645
Length = 256
Score = 111 bits (268), Expect = 1e-23
Identities = 65/225 (28%), Positives = 115/225 (51%), Gaps = 8/225 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLD 83
++ GA++++ RN E L + + + D+TK +E ++ ++ + KLD
Sbjct: 35 MASRGAKVAVVARNAEKLADTVAIIEAAGGVAQAYSCDVTKRESVEAVVDAVMEKWEKLD 94
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 142
VLVNNAG+ + + ++D ++ TN+R ++ T A ++ ++ G G
Sbjct: 95 VLVNNAGVTRDNLLPVMTDDEWDNVIETNLRGMFLFTRAASKQMMRARFGRIINISSVSG 154
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+ PG Y+ SKA + FTR ++ EL + V VN + PG I +++ + G A
Sbjct: 155 LMGNPGQTNYSASKAGMIGFTRSLSRELGKRKVTVNAICPGFIESDMTKALG------PA 208
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
++ K+ R GKP+E+A + FLAS A+ ITG + +DGG
Sbjct: 209 VMDEVKKRIPAQRMGKPEEIADGVLFLASPQAAYITGQVLTIDGG 253
>UniRef50_Q9A872 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=18;
Bacteria|Rep: 2-deoxy-D-gluconate 3-dehydrogenase -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 255
Score = 111 bits (267), Expect = 2e-23
Identities = 71/248 (28%), Positives = 118/248 (47%), Gaps = 10/248 (4%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV L+ GA ++ GR+ + + + LSI AD +
Sbjct: 9 GKVALITGANTGIGQGIAIALAAAGADIAAAGRSAPTETQAAVEA-LGRKFLSIKADFSS 67
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
+++++ +T+ +GK+D+LVNNAGII S A +D +M+TN++ +++LT
Sbjct: 68 IEPVQRVVDETVAAFGKVDILVNNAGIIRRADSIEFSEADWDAVMDTNLKVVFFLTQAFA 127
Query: 125 PHLLES--KGXXXXXXXXXGIRSFPG---VLAYNISKASVDQFTRCVALELAPKGVRVNC 179
L+ +G + SF G V +Y SK+ + T+ +A E A KG+ VN
Sbjct: 128 KQALKQGFEGGQAKVINIASLLSFQGGIRVPSYTASKSGLAGLTKILANEWATKGINVNA 187
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
+ PG T +++ AA L R GR G+P+++ FLAS + + G
Sbjct: 188 IAPGYFDTNNTEALRADQDRNAAILARI----PAGRWGRPEDIGGAAVFLASSASDYVQG 243
Query: 240 ASVPVDGG 247
++PVDGG
Sbjct: 244 ITLPVDGG 251
>UniRef50_Q89UV5 Cluster: Dehydrogenase; n=12;
Alphaproteobacteria|Rep: Dehydrogenase - Bradyrhizobium
japonicum
Length = 268
Score = 111 bits (267), Expect = 2e-23
Identities = 68/227 (29%), Positives = 116/227 (51%), Gaps = 8/227 (3%)
Query: 29 GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GAQ+ RN ++ +K D+ + TAD+++ ++IE ++ + YG++DVL N
Sbjct: 35 GAQVFCVDRNGTAAEETAKIINDEGGKATAFTADVSRSAEIEAMVAACLKAYGRIDVLDN 94
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 147
N GI E G++ + +DR+ + N++S Y+ +P ++E G
Sbjct: 95 NVGIAEMGSVVEVTEESWDRVFSVNLKSAYFAMKHVIPVMVEQGGGSIINISSIASIRHM 154
Query: 148 GV--LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL-QRRGGLSEEQYAAFL 204
G+ + Y SKA+++Q TR A+E A VRVN + PG++ T + + GL+ +
Sbjct: 155 GISYVTYGTSKAAMNQMTRTTAIEFARHHVRVNAILPGLMKTPMVEHSAGLAASYAKGDV 214
Query: 205 E---RTKETHA-LGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E R ++ +G G +VA FLASD + +TG + VDGG
Sbjct: 215 EAMWRARDAQVPMGHMGDAFDVANAALFLASDESKYVTGIELVVDGG 261
>UniRef50_Q47PV9 Cluster: Short chain dehydrogenase; n=1;
Thermobifida fusca YX|Rep: Short chain dehydrogenase -
Thermobifida fusca (strain YX)
Length = 262
Score = 111 bits (267), Expect = 2e-23
Identities = 70/200 (35%), Positives = 103/200 (51%), Gaps = 7/200 (3%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-----TGTIENTSLAQYDRLMNT 111
++ DL + + +++++ + G LD LVNNAG+++ T T+E +DR+
Sbjct: 58 AVAVDLADSAQVRRMVEEAVAAGGGLDTLVNNAGVLDSAFTDTPTVEELPEEAWDRVYAV 117
Query: 112 NVRSIYYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL 170
NV++++ T A PHL S +G + G AY SK +V Q TR +A+ L
Sbjct: 118 NVKAVWLATKFAAPHLRASERGPSVVNAASVAGMTGYGSPAYASSKGAVIQLTRSMAIAL 177
Query: 171 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 230
+P+ VR N PG I T + R + E A L H + R G+P EVA + FLA
Sbjct: 178 SPQ-VRCNAYCPGSIETPMSRAHLEASEDREARLRSMIGAHLIPRFGRPSEVAKVVCFLA 236
Query: 231 SDLASNITGASVPVDGGRHA 250
SD AS +TG PVDGG A
Sbjct: 237 SDDASFVTGGIFPVDGGTTA 256
>UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier
protein) reductase - Leptospira interrogans
Length = 259
Score = 111 bits (266), Expect = 2e-23
Identities = 69/226 (30%), Positives = 113/226 (50%), Gaps = 7/226 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 82
++K G + L N E +++ + D K TL ++ ++TK D + +I + +GKL
Sbjct: 33 IAKEGGDIVLVDLNKEQIEQAAADVAKEFGVKTLGLSCNVTKPEDCDSVIAGVKEKFGKL 92
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 141
D LVNNAG+++ S ++D +++ N++ ++ +T A LL+++ G
Sbjct: 93 DFLVNNAGVLKDNLFIRMSEQEFDFVLDVNLKGVFLMTKYASKLLLKAESGRIVNISSVS 152
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G+ PG Y+ SKA V T+ A E A + V VN V PG + T++ L EE
Sbjct: 153 GLTGQPGQANYSSSKAGVIALTKVAAREFAGRNVLVNAVCPGYVQTDM--TASLPEEVQK 210
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ L RPG E+A + F SD ++ ITG + VDGG
Sbjct: 211 KLTD--PAFIPLRRPGTQQEIANAVKFFLSDQSNYITGTYLRVDGG 254
>UniRef50_Q9REP0 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Zymomonas
mobilis
Length = 243
Score = 111 bits (266), Expect = 2e-23
Identities = 65/195 (33%), Positives = 105/195 (53%), Gaps = 7/195 (3%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
LSI AD + +K+I +T H+G++DVLV NAG++ I+ S+ + ++N N+RS
Sbjct: 56 LSIQADGSTVEGNKKVISETAKHFGRVDVLVCNAGMLSYKNIDQVSVDDINDMLNLNLRS 115
Query: 116 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 175
+ AV HL G F G+ Y+ +KA + F + VA +L K +
Sbjct: 116 VMVEVSEAVRHLPSGGRIILIGSTFAGRAPFAGISLYSAAKAGLRGFAKGVARDLGQKAI 175
Query: 176 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
+N + PG I T++ G + + ++F TK+ G+ D++A T++FLAS +
Sbjct: 176 TINVIEPGPINTDMNPADGEAFDLISSF-TATKDY------GQVDDIARTVSFLASSESG 228
Query: 236 NITGASVPVDGGRHA 250
NITGA++ VDGG A
Sbjct: 229 NITGAAIAVDGGLQA 243
>UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Rhodopseudomonas palustris BisB18|Rep: Short-chain
dehydrogenase/reductase SDR - Rhodopseudomonas palustris
(strain BisB18)
Length = 254
Score = 111 bits (266), Expect = 2e-23
Identities = 65/195 (33%), Positives = 95/195 (48%), Gaps = 6/195 (3%)
Query: 53 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 112
A +++ D++ D ++ + + +G++DVLVN AG+ E E T LA + +TN
Sbjct: 64 AQGIAVAGDISNSEDARAMVGEVVARFGRIDVLVNCAGVAEYRAFEATDLAMFRATFDTN 123
Query: 113 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 172
V + A+PHL G R P Y SKA+V T +A E P
Sbjct: 124 VFGTVAMIQAALPHLTAPGGRIINFSSALATRPIPTASIYAASKAAVSALTHALAKEFGP 183
Query: 173 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 232
+G+ VN + PGVI TE+ + E+ AA K LGR G+ D+VA FLAS
Sbjct: 184 RGITVNAIAPGVIETEM--TAAILAERGAAI----KAMTPLGRIGQTDDVAGLALFLASH 237
Query: 233 LASNITGASVPVDGG 247
A +TG ++ DGG
Sbjct: 238 DAGWLTGRTIIADGG 252
>UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=28; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 253
Score = 111 bits (266), Expect = 2e-23
Identities = 75/229 (32%), Positives = 118/229 (51%), Gaps = 10/229 (4%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDV 84
++LGA++ + E Q+V+ + +++ D+T+++ + ++ + +G+LD+
Sbjct: 27 AELGAKVVVADLRAEAAQQVAAAIESAGGQAIAVHVDVTQDASVADMVAAAVKRFGRLDI 86
Query: 85 LVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX-XXXXG 142
LVNNAG + T +DR+ TNV+SIY AVP + G G
Sbjct: 87 LVNNAGTTHKNQPMLETDEKTFDRVYATNVKSIYLGARHAVPLFRQQGGGVIINIASTAG 146
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR---GGLSEEQ 199
+R PG+ Y +K + T+ +A+ELAP +RVN +NP + T L G SEE
Sbjct: 147 LRPRPGLSWYAGTKGAAITLTKAMAVELAPDKIRVNAINPVMGETGLLADFLPGADSEE- 205
Query: 200 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
++ T LGR KP ++A AFLASD A ITG ++ VDGGR
Sbjct: 206 ---VRQKIIATIPLGRLSKPIDIAKATAFLASDEADFITGVALEVDGGR 251
>UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Solibacter usitatus Ellin6076|Rep: Short-chain
dehydrogenase/reductase SDR - Solibacter usitatus
(strain Ellin6076)
Length = 251
Score = 111 bits (266), Expect = 2e-23
Identities = 69/225 (30%), Positives = 117/225 (52%), Gaps = 6/225 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI-TADLTKESDIEKIIKKTIDHYGKLD 83
L+ G +++L R+ L +V+ + +I AD+T E + + + + YGK+D
Sbjct: 27 LAAEGTRIALVSRDEARLNEVAAELIAAGGDAAIFRADVTSEEQVRQAERAILATYGKVD 86
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG 142
+L+NNAG+ + ++ ++ R+M+TNV + + + VP + G
Sbjct: 87 ILINNAGVNVRKPVVEFTVEEWHRVMDTNVTAAFLMCRSFVPAMSGRGYGRILNMTSIMS 146
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
S PG +AY+ SK ++ TR +ALELAP+G+ VN ++PG TE+ + + E A
Sbjct: 147 HVSLPGRIAYSTSKTALLGMTRTLALELAPQGITVNGISPGPFGTEMNKPLMENPETNAQ 206
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
FL + LGR GK +E+ +L S+ A ITG + +DGG
Sbjct: 207 FL----SSIPLGRWGKVEEIGQLAVYLCSEDAGFITGTDILIDGG 247
>UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=4; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 254
Score = 111 bits (266), Expect = 2e-23
Identities = 73/226 (32%), Positives = 118/226 (52%), Gaps = 6/226 (2%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA++ LT R++ +KV++ ++ D+T E+ +++ GKLDVLVN
Sbjct: 32 GAKVWLTDRDLAGAEKVAEGIRAAGGQARALLHDVTNEAQWDEVFAAIEAEDGKLDVLVN 91
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRS 145
NAGI I + A ++ + N+ S++ T AV + ++ KG G+
Sbjct: 92 NAGIAVLRPIAEMTTADWNLQNSVNLDSVFQGTKRAVVLMRKTGTKGSIINISSVAGLIG 151
Query: 146 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 205
P AY +K V F++ +A+E A G+RVN V+PG+ILT +Q G+++E AA +
Sbjct: 152 VPACGAYAAAKGGVRLFSKTIAVETAKDGIRVNSVHPGMILTNIQ---GVAQEDNAANYD 208
Query: 206 RTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHAM 251
T +G G P ++A FLASD + +TG + VDGG A+
Sbjct: 209 ATLALVPMGYMGDPLDIANMNLFLASDESRYVTGTELVVDGGMTAL 254
>UniRef50_A4FIJ5 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Saccharopolyspora
erythraea NRRL 2338|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 253
Score = 111 bits (266), Expect = 2e-23
Identities = 72/247 (29%), Positives = 113/247 (45%), Gaps = 7/247 (2%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITAD 61
+ G+V L + GA+L +T R + + D D A+ + D
Sbjct: 9 DLTGRVAVVTGAARGIGRATAALLRERGARLVVTDRREAVEELAADDPDDVAA---LVGD 65
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
+ E + +G+LD+LVNNAG + +T++ +D +M N R +
Sbjct: 66 VADEDIARAATRLATQRFGRLDILVNNAGRTLNKPVTDTTVDDFDEIMRVNARGNFVQAR 125
Query: 122 LAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
A + G + +F AY SK ++ Q TR +A+E PKG+R N V
Sbjct: 126 EAFRAMEAGGGGAIVSIASVSSVVAFRTQTAYAASKGALAQITRVLAIEGGPKGIRSNAV 185
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PGV+ T++ G+ ++ L H +GR GKP+EVA +AFL D ++ +TGA
Sbjct: 186 LPGVVDTDIME--GVVDDG-REMLASFGSAHPIGRIGKPEEVAEAVAFLVCDASAFVTGA 242
Query: 241 SVPVDGG 247
V VDGG
Sbjct: 243 LVAVDGG 249
>UniRef50_A1SC75 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Nocardioides sp. JS614|Rep: Short-chain
dehydrogenase/reductase SDR - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 244
Score = 111 bits (266), Expect = 2e-23
Identities = 67/196 (34%), Positives = 106/196 (54%), Gaps = 8/196 (4%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTIENTSLAQYDRLMNTN 112
LS+ AD+T + +E ++ +D +G++D+LVNNAGI E +T + Q+D + N
Sbjct: 49 LSLEADVTDPAGVESAVEAILDAFGRVDLLVNNAGITGSAEATVCHDTPVEQWDLVHAVN 108
Query: 113 VRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
VR + T +P +L K G G+ +FPG AY SK + FTR +A++ A
Sbjct: 109 VRGPFLCTRAVLPTMLIQKSGHVITVASVAGLVAFPGRCAYTASKGAAIAFTRSLAVDYA 168
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
GVR N + PG++ T + + L + A +E LGR KP+++A + LAS
Sbjct: 169 AAGVRANAICPGMVETPM-TQWRLDVPELRAQVE---SKIPLGRVAKPEDIADAVVALAS 224
Query: 232 DLASNITGASVPVDGG 247
D + +TG ++ VDGG
Sbjct: 225 DKLAYMTGHALVVDGG 240
>UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1;
marine gamma proteobacterium HTCC2143|Rep: Short-chain
dehydrogenase/reductase - marine gamma proteobacterium
HTCC2143
Length = 264
Score = 111 bits (266), Expect = 2e-23
Identities = 82/257 (31%), Positives = 119/257 (46%), Gaps = 12/257 (4%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV K GA + LTGR+ E Q ++ A I AD++K
Sbjct: 7 GKVAIITGGTSGIGEATADIYIKEGATVVLTGRSEEKGQAIANRLGDKAHY--IKADVSK 64
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
E DI I +T++ +GKLDVL NNAG GTI++ + + ++ + S+ A+
Sbjct: 65 EEDIANTISETVERFGKLDVLFNNAGGPVGGTIDSIAPGDINYGVDLLLSSVVLGIRYAI 124
Query: 125 -PHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 183
P G IR G L Y+ KA+V +T+ +EL P G+RVNC++PG
Sbjct: 125 EPMKANGGGVIINNTSIAAIRYRQGNLLYSALKAAVTHYTKLAGVELGPLGIRVNCISPG 184
Query: 184 VILTELQRRGGL-----SEEQYAAFLERTKETHA----LGRPGKPDEVAATIAFLASDLA 234
I T + G ++E A LE+ K A L PG +++A FLASD
Sbjct: 185 AIATPIFWGGSAIANTKTDEDNARKLEKLKANLAKATPLQIPGLAEDIANGALFLASDEG 244
Query: 235 SNITGASVPVDGGRHAM 251
I + +DGGR +M
Sbjct: 245 RFINSHDLVIDGGRTSM 261
>UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1;
Methanobrevibacter smithii ATCC 35061|Rep: Short chain
dehydrogenase - Methanobrevibacter smithii (strain PS /
ATCC 35061 / DSM 861)
Length = 269
Score = 111 bits (266), Expect = 2e-23
Identities = 70/224 (31%), Positives = 110/224 (49%), Gaps = 10/224 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA++ + GR E Q V + K S D+T + IEK+I T + YGK+D+LVN
Sbjct: 32 GAKVVICGRREEKGQAVVDNITKEGGESSYHFFDITNTNSIEKLIDDTAEKYGKIDILVN 91
Query: 88 NAG--IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL--ESKGXXXXXXXXXGI 143
NA ++ G I+ ++ +D + +++R +Y T +P+L E+ G
Sbjct: 92 NAANVALKDGNIDELTIDMWDAIFESDLRGTFYATKCVIPYLQKNENGGSIINIGSMASC 151
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 203
G AY +K+ VD FT+ AL+ +R NCV PG+I+T + + E F
Sbjct: 152 GGDLGSTAYACAKSGVDMFTQYTALQYGKDNIRCNCVRPGLIVTP-ENEANVPEVLRNIF 210
Query: 204 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
L + R G P+++ +LASD + +TG V VDGG
Sbjct: 211 LNNI----MVNRYGGPEDIGHMCVYLASDESEYVTGQIVNVDGG 250
>UniRef50_Q3WHY3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 346
Score = 110 bits (265), Expect = 3e-23
Identities = 69/222 (31%), Positives = 104/222 (46%), Gaps = 3/222 (1%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
G +++TG+N E L L AD +D + + + D +G LD + N
Sbjct: 126 GFAVAITGQNPETLAAARHVLPD--DVLVQRADARVLADADALAAELRDRFGHLDAVFLN 183
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 148
A + + + + + Y NV+ ++ +P LL G RSFPG
Sbjct: 184 AAVAQPSSFSSVTEESYKEHFGVNVKGQFFTLQRVLP-LLRDGGTVVFNSSRLVARSFPG 242
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 208
+ Y +K +V R +A+ELAP+ +RVN V+PG + T + GLS + +
Sbjct: 243 MSLYVATKGAVASMARALAVELAPRRIRVNVVSPGPVDTPALAKQGLSAAELTSLRTTLT 302
Query: 209 ETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGRHA 250
LGR +EVA T+AFL SD AS +TGA + VDGG A
Sbjct: 303 AKVPLGRIASDEEVAHTVAFLVSDAASYLTGADIVVDGGMMA 344
>UniRef50_Q3WEN2 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Frankia sp.
EAN1pec
Length = 312
Score = 110 bits (265), Expect = 3e-23
Identities = 75/252 (29%), Positives = 116/252 (46%), Gaps = 7/252 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT-AD 61
FAGKVV ++ GA++ GR E ++V ++ + T AD
Sbjct: 56 FAGKVVLVTGATSGIGRAAAIAFAREGARVGFCGRREELGRRVEEEIRAAGGEATYTRAD 115
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
+ + +E + D YG+LDV +NNAG + ++ ++D +TN R ++
Sbjct: 116 VRDPAQVESFVAGVADRYGRLDVALNNAGTQIVKPLHEMTVEEWDDTAHTNTRGVFLAIK 175
Query: 122 LAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
VP + ES G S PG+ AY+ SK V R AL+ +RV +
Sbjct: 176 YEVPPMRESGGGVILVTGSANEFASRPGLGAYSASKGGVTGLVRTAALDYGQDNIRVAAL 235
Query: 181 NPGVI---LTELQRRGGLSEEQYAAFLER--TKETHALGRPGKPDEVAATIAFLASDLAS 235
+PG L + +R +++EQ+AA + AL R +P+E+AA LAS S
Sbjct: 236 SPGTTDTGLVDRRRPPNITDEQWAAGKAQYGADNVDALRRMARPEEMAAAALALASPDMS 295
Query: 236 NITGASVPVDGG 247
+TG SV VDGG
Sbjct: 296 FLTGTSVLVDGG 307
>UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=4;
Bradyrhizobiaceae|Rep: Short-chain
dehydrogenase/reductase - Rhodopseudomonas palustris
(strain HaA2)
Length = 259
Score = 110 bits (265), Expect = 3e-23
Identities = 74/250 (29%), Positives = 119/250 (47%), Gaps = 4/250 (1%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
G+V L++ GA++ R+ L + A L++TAD+T+
Sbjct: 9 GRVALVTGAAGVIGRATIDLLAERGARIVAIDRDRTALDQAVAALPASAQPLALTADVTQ 68
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLA 123
E + ++ ++ G++DV NNAGI + I TSL + R+++ NV ++
Sbjct: 69 EDQVAAYVRAALERCGRIDVFYNNAGIEGDIAPIVRTSLDAFRRVLDVNVVGVFLGMKHV 128
Query: 124 VPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
+P +L+ G G+ ++AY SK +V T+ ALE GVRVNCV P
Sbjct: 129 LPAMLQLGSGSIINTASIAGLIGSNDIIAYTASKHAVIGMTKTAALECGDSGVRVNCVCP 188
Query: 183 GVILTELQRR--GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
G+I + + G + ++ + R G EVA+ +AFLASD AS ++GA
Sbjct: 189 GLIDSRMLSAIVEGRNPGPTPVPNDKIVDRIPARRLGHAAEVASVVAFLASDEASYVSGA 248
Query: 241 SVPVDGGRHA 250
+ VDGGR A
Sbjct: 249 AYTVDGGRTA 258
>UniRef50_Q1QUQ5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Chromohalobacter salexigens DSM 3043|Rep:
Short-chain dehydrogenase/reductase SDR -
Chromohalobacter salexigens (strain DSM 3043 / ATCC
BAA-138 / NCIMB13768)
Length = 255
Score = 110 bits (265), Expect = 3e-23
Identities = 70/251 (27%), Positives = 119/251 (47%), Gaps = 5/251 (1%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGR---NVENLQKVSKDCDKFASTL- 56
M F G+ V + GA++++ R +VE + + + ++T+
Sbjct: 1 MTFTGQRVLVTGGARGIGAATARRFLEQGARVAIGARREASVEAFRDSLANTELASATVE 60
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 116
S ++ +++ +++ + G LD+LVN AG+ E E + +D NV
Sbjct: 61 SAVGEIGTQAECRAVVETAVARLGGLDILVNCAGVFEEVPFEAVTQEHWDSTFRVNVGGT 120
Query: 117 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
++ A+PHL S G G+ FP Y+ +KA+V TR +ALELA + +R
Sbjct: 121 FFCLQAALPHLEASGGNVVNLGSDAGLIGFPPSSVYSGAKAAVVNLTRALALELAGR-IR 179
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
+NCV PG + T++ + + + A+L+ L R GKP E+A + +LAS A
Sbjct: 180 INCVCPGNVETDMIQHAAEASGEPHAYLDAAHRRAPLQRMGKPQEIADAVLYLASPQAGF 239
Query: 237 ITGASVPVDGG 247
GA + VDGG
Sbjct: 240 THGAILSVDGG 250
>UniRef50_Q1JZ17 Cluster: Short-chain dehydrogenase/reductase SDR;
n=6; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Desulfuromonas acetoxidans
DSM 684
Length = 252
Score = 110 bits (265), Expect = 3e-23
Identities = 65/196 (33%), Positives = 102/196 (52%), Gaps = 5/196 (2%)
Query: 54 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GT-IENTSLAQYDRLMNT 111
S + D++ E ++ + YG+LD+LVNNA + + GT +E+ +L ++ L+N
Sbjct: 51 SVIGKLVDVSDEKAVQLLFSWLEATYGRLDLLVNNAAVAKAHGTPLESLALEEWQHLLNV 110
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + + A P L G ++S P AY SK V T +AL L
Sbjct: 111 NLTGPFLCSKYAAPLLRHPSGSIIHIASTRAVQSEPDSEAYAASKGGVVALTHAMALSLG 170
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
P+ +RVNC++PG I ++G Q + + E H +GR G+P ++AAT+ FLAS
Sbjct: 171 PQ-IRVNCISPGWIDVSALKKGAHGISQ--SLSRQDHEQHPVGRVGQPQDIAATVCFLAS 227
Query: 232 DLASNITGASVPVDGG 247
A ITG ++ VDGG
Sbjct: 228 AQAGFITGQNLVVDGG 243
>UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 252
Score = 110 bits (265), Expect = 3e-23
Identities = 64/217 (29%), Positives = 106/217 (48%), Gaps = 3/217 (1%)
Query: 32 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 91
+ L G +E+L SK L++ D+++ +D++ + I +GK+D+L NNAGI
Sbjct: 35 IDLDGGKLEHL--ASKITSSGGICLALRGDVSQSADVQNALNTAIGRFGKIDILFNNAGI 92
Query: 92 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVL 150
+ G I+ T+ Q+DR M NV+S+Y VPH E G +R+
Sbjct: 93 VPAGKIDVTTEEQWDRAMAINVKSMYLFCHAIVPHFKEHGGGVILNTASATALRAVVDRA 152
Query: 151 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 210
Y +KA+V T+ +AL+ +RVNC+ PG + T + A +
Sbjct: 153 CYTATKAAVVGLTKSMALDYVRDNIRVNCLCPGTVDTPSLSERLAAFPDPAEAKKNFIAR 212
Query: 211 HALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+GR G +E+A +L SD ++ +TG + +DGG
Sbjct: 213 QPMGRFGTAEEIALAALYLVSDESAFVTGVAFAIDGG 249
>UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase
precursor; n=2; Clostridium difficile|Rep: Probable
short chain dehydrogenase precursor - Clostridium
difficile (strain 630)
Length = 245
Score = 110 bits (265), Expect = 3e-23
Identities = 64/199 (32%), Positives = 107/199 (53%), Gaps = 7/199 (3%)
Query: 50 DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLM 109
+K S A+++ D+E ++ I +G LDVLVNNAG+ + + + +D +M
Sbjct: 50 EKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITDEDWDNMM 109
Query: 110 NTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 168
N N++ +Y + +A+ +++ E KG GI + Y+I+KA + T+ +A
Sbjct: 110 NINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGIIGMTKALAK 169
Query: 169 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAF 228
E+ P +RVN + PGVI T++ G +EE A +E T L R G P+++A F
Sbjct: 170 EVGPSNIRVNSIAPGVINTDM--LSGYNEEDIDALVEET----PLMRLGTPEDIANCAIF 223
Query: 229 LASDLASNITGASVPVDGG 247
LASD ++ ITG + +GG
Sbjct: 224 LASDKSNFITGQVISPNGG 242
>UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase;
n=1; Burkholderia xenovorans LB400|Rep: Putative
short-chain type dehydrogenase - Burkholderia xenovorans
(strain LB400)
Length = 252
Score = 110 bits (265), Expect = 3e-23
Identities = 65/196 (33%), Positives = 98/196 (50%), Gaps = 11/196 (5%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
+ D+T E+ + +I + ++ G LD L NAG+ +G I A +D L N R+ +
Sbjct: 58 VQVDVTSEASVANLIARGVEWLGGLDALAQNAGLQRSGAIAGFEQANWDALFAVNARAHF 117
Query: 118 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
+ A+PHL S KG G R PG++AY+ SK +V FT +ALELAP +R
Sbjct: 118 FGAKHAIPHLQRSGKGSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALALELAPDNIR 177
Query: 177 VNCVNPGVILTELQR-----RGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
VN + PG + T + GG +Q ++ LGR E+A +LAS
Sbjct: 178 VNAICPGWVDTAFNQPAIDFMGGADAQQ-----KKIASLVPLGRQASATEIAPLFVYLAS 232
Query: 232 DLASNITGASVPVDGG 247
D ++ +T S +DGG
Sbjct: 233 DESAYVTAQSFGIDGG 248
>UniRef50_A5FD58 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Bacteroidetes|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Flavobacterium
johnsoniae UW101
Length = 247
Score = 110 bits (265), Expect = 3e-23
Identities = 75/247 (30%), Positives = 113/247 (45%), Gaps = 7/247 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
M+F K V K GA + +TGRN ENL+K + + + +I +
Sbjct: 1 MDFTNKNVLITGGTTGIGLATAKEFIKAGANVWITGRNSENLEKAANEINS-QKLKTIVS 59
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D SD+ + K ++ LDVL NAGI +IE+ + A +D NTNV+ ++
Sbjct: 60 DTANLSDLSLLEKAFAENNAPLDVLFLNAGIARFTSIEDVTEADFDAQFNTNVKGHFFTL 119
Query: 121 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
+PHL E + G Y+ +K ++++ + A ELA + +RVN V
Sbjct: 120 QKLLPHLAEGSSVIFTSSTVATASNL-GSSIYSATKGALNKIAQIAANELAGRKIRVNIV 178
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
+PG + T GL E A+ R G E+A T+ FLAS+ AS ITG
Sbjct: 179 SPGPVSTP-----GLHNAVPEEAKEYLAGATAMQRLGDSSEIAKTVLFLASENASFITGT 233
Query: 241 SVPVDGG 247
+ DGG
Sbjct: 234 ELLADGG 240
>UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Sphingomonadaceae|Rep: Short-chain
dehydrogenase/reductase SDR - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 261
Score = 110 bits (265), Expect = 3e-23
Identities = 68/255 (26%), Positives = 118/255 (46%), Gaps = 9/255 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITAD 61
+ GKV L+ GA + + R + L+ + K ++ D
Sbjct: 4 DMTGKVAIVTGGSDGIGLATARLLAARGATVVICARREDKLEAARAEIAKVGKVEAVKLD 63
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
++ E+ +++ +G+LD+LVNNA + I L + + N +++ T
Sbjct: 64 VSDEAAFTALVEDVAARHGRLDMLVNNAMSVHYAPIAKLRLDHWRKDFAVNADAVFVGTK 123
Query: 122 LAVPHLL------ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 175
A+ + +G GIR+ P + +Y+ SKA++ FT A+E AP G+
Sbjct: 124 AAMKVMAAQEQRGRQRGAIVNIASTCGIRAAPNMASYSASKAAMVHFTAAAAMEGAPLGI 183
Query: 176 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
RVN + PG ++T + + AA RT + R G+P+E+A I F+ S+ AS
Sbjct: 184 RVNAIVPGQVMTAATQEFADRAPEVAA---RTTGAIPMQRGGEPEELAEAIVFMLSEAAS 240
Query: 236 NITGASVPVDGGRHA 250
+TG ++PVDGG+ A
Sbjct: 241 YVTGTALPVDGGKAA 255
>UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Comamonas testosteroni KF-1|Rep: Short-chain
dehydrogenase/reductase SDR - Comamonas testosteroni
KF-1
Length = 263
Score = 110 bits (265), Expect = 3e-23
Identities = 64/199 (32%), Positives = 104/199 (52%), Gaps = 5/199 (2%)
Query: 50 DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRL 108
D + LS+ D+T E+ IE + K D +G+ D+LVNNAG++ +E +A +D++
Sbjct: 54 DNAQAALSLACDITDEAAIEAMAAKVKDTFGRCDILVNNAGVMAPVVPLEELPVAMWDKV 113
Query: 109 MNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 168
M+ N+R + V +LE K G R + Y SKA V T +A+
Sbjct: 114 MSVNLRGSFLCAKYLVRMMLEQKRGAIVNLASIGARVPNDIGPYGPSKAGVLGLTHQMAV 173
Query: 169 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAF 228
E P+GVR N ++PG+I T + +E+ + R K +GR G+P+++A + F
Sbjct: 174 EWGPRGVRTNSISPGMIRTPMSEHFYQNEKLHQG---RIKVV-PVGRIGRPEDIADAMGF 229
Query: 229 LASDLASNITGASVPVDGG 247
+ SD AS + G + +DGG
Sbjct: 230 IVSDAASYMNGQDIIIDGG 248
>UniRef50_Q89W00 Cluster: Blr0893 protein; n=7;
Bradyrhizobiaceae|Rep: Blr0893 protein - Bradyrhizobium
japonicum
Length = 279
Score = 110 bits (264), Expect = 4e-23
Identities = 72/226 (31%), Positives = 116/226 (51%), Gaps = 10/226 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++ + GR + + ++K A+ + D+T E+ ++ +I +D +G++D L NN
Sbjct: 30 GAKIVIAGRRLPEGEALAKQLG--ANCIFRQTDVTVEAQMQALIALAVDKFGRIDCLFNN 87
Query: 89 AG-IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG-IRS 145
AG +TG IE + ++D M T VRS+ A P++ + G G +
Sbjct: 88 AGGPAQTGGIEGLEVERFDAAMATLVRSVMLGMKHAAPYMKKQGSGSIINNGSIAGRLAG 147
Query: 146 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRG-GL----SEEQY 200
F + Y +KA+V T+CVA+EL VRVN ++PG I T + + GL +E+
Sbjct: 148 FSSSVVYGAAKAAVIHLTKCVAMELGESNVRVNSISPGAIATGIFGKALGLATSAAEKTP 207
Query: 201 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDG 246
A E K + R G PD++A FLASD +S I G + +DG
Sbjct: 208 AVMREVYKTAQPIPRAGIPDDIAHAAVFLASDESSFINGHDLVIDG 253
>UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Geobacter metallireducens GS-15|Rep: Short-chain
dehydrogenase/reductase SDR - Geobacter metallireducens
(strain GS-15 / ATCC 53774 / DSM 7210)
Length = 254
Score = 110 bits (264), Expect = 4e-23
Identities = 63/248 (25%), Positives = 119/248 (47%), Gaps = 6/248 (2%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITA 60
N GKV L++ GA + + R +L V+++ +L++
Sbjct: 7 NLEGKVAIVTGGSRGFGKAIALGLAQAGADVVVASRTQADLDAVAEEIRALGRKSLAVAT 66
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+ IE + KT++ +GK+D+LVNNAG T + Q+D++++ N++ + T
Sbjct: 67 DMLDRGSIENLAAKTMEAFGKIDILVNNAGQGWTVPFLKWTDEQWDQILDVNLKGYFLCT 126
Query: 121 MLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+ H+ ++K G G P ++ Y SK ++ T+C+A E A +G+ VN
Sbjct: 127 QIVGQHMFKAKAGRVINISSAMGSYPLPYMVPYAASKGGINAMTKCLAQEWATRGITVNA 186
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
+ P T++ + E + +T + R G +E+ + +L+S+ +S +TG
Sbjct: 187 IAPSYFSTDINKDAMEDEATTKLIMSKT----PVNRWGNVEELVGLVIYLSSNASSFMTG 242
Query: 240 ASVPVDGG 247
A +P+DGG
Sbjct: 243 AVLPLDGG 250
>UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR;
n=9; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Herpetosiphon aurantiacus ATCC 23779
Length = 257
Score = 110 bits (264), Expect = 4e-23
Identities = 69/249 (27%), Positives = 122/249 (48%), Gaps = 7/249 (2%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITA 60
+ +GKV ++ GA++ + R +E+LQ V+ ++ T L++
Sbjct: 5 DLSGKVAIVTGASRGIGEAIAQHFAQAGAKVVVCARKLESLQTVADSINQAGGTALAMAC 64
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 119
K ++ ++ +T+ +G++D++VNNA G + N+ +Q+D+ NV+ ++L
Sbjct: 65 HTGKPEQVQAVVAQTLAEWGRIDIVVNNAATNPHFGPLLNSDASQWDKTYEVNVKGYFWL 124
Query: 120 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
A + + G G++ + Y+ISKA+V T+ +A EL P +RVN
Sbjct: 125 IQAAAEAMQAQGGGSIINVASVAGLQPATAMGIYSISKAAVIAMTKQLAQELGPMNIRVN 184
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
+ PG+I T+ +E+ + T LGR G DEVAA +LASD A+ T
Sbjct: 185 ALAPGLIKTKFSSALWDNEDLNQKIVAGT----PLGRIGTVDEVAAAALYLASDAAAFTT 240
Query: 239 GASVPVDGG 247
G + +DGG
Sbjct: 241 GTVITMDGG 249
>UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Sinorhizobium medicae
WSM419
Length = 251
Score = 110 bits (264), Expect = 4e-23
Identities = 61/193 (31%), Positives = 105/193 (54%), Gaps = 5/193 (2%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
+++ AD++ ++++ + K D +G LD +VNNAGI+ +G +E +D +M+ N +
Sbjct: 59 ITVCADVSSKAEVRAMAKAVGDAFGHLDAVVNNAGILISGDVEGLDEEHWDSVMDVNAKG 118
Query: 116 IYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 174
+ + +P + + G G P Y+ SKA+V FTR +A E+ G
Sbjct: 119 TFLVVQAVLPMMKARRYGRIVNIASIGGKHGAPEQAHYSASKAAVMGFTRVLAQEVGVDG 178
Query: 175 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
+ NCV PG+ILT++ R L + A + ++ A+ R G P++V +AF ASD A
Sbjct: 179 ITANCVCPGIILTDM-GRVNLDD---PAVKKSWQDKTAMRRIGDPEDVVGAVAFFASDDA 234
Query: 235 SNITGASVPVDGG 247
+ +TG ++ VDGG
Sbjct: 235 AFVTGQTLNVDGG 247
>UniRef50_A6UBN3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Sinorhizobium medicae
WSM419
Length = 253
Score = 110 bits (264), Expect = 4e-23
Identities = 75/246 (30%), Positives = 112/246 (45%), Gaps = 4/246 (1%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITAD 61
N+ GK L + GA++ LTGR+ N+ ++ ++ LS +D
Sbjct: 3 NYQGKKAIIVGGTHGMGLATVRRLVEGGAEVLLTGRSESNIARIREEFGPRVHALS--SD 60
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
+ +DI + G +D+L NAGI E + S A YDR + N + ++
Sbjct: 61 IAHLNDIAILGAAAGQKLGAIDLLHINAGISELEPFDQVSEASYDRQFSVNTKGAFFTVQ 120
Query: 122 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
P L+ G G+ Y+ SKA++ F +A EL P+G+RVN V+
Sbjct: 121 RLAP-LIREGGSIVFTSSVADEGGHQGMSVYSASKAALVSFASVLAAELLPRGIRVNSVS 179
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG I T + GL+E Q A F + R G DEVA + FLA + A+ TGA
Sbjct: 180 PGFIDTPTKGAAGLTEAQRAEFKALGDAITPMRRNGTADEVARAVLFLAFE-ATFTTGAK 238
Query: 242 VPVDGG 247
+ VDGG
Sbjct: 239 LAVDGG 244
>UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Sphingomonas wittichii RW1|Rep: Short-chain
dehydrogenase/reductase SDR - Sphingomonas wittichii RW1
Length = 250
Score = 110 bits (264), Expect = 4e-23
Identities = 60/188 (31%), Positives = 94/188 (50%), Gaps = 2/188 (1%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
AD+T + + + YG+ D+LVNNAG++ I ++DR+ N +S + +
Sbjct: 62 ADVTSAVQVATLGQHVRSAYGRADILVNNAGMLSFAPIVGADANEWDRVQKVNCKSAFLM 121
Query: 120 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
P L+ KG G++ AY+I+KA + T+ A+EL P G+RVN
Sbjct: 122 IRTFAP-LMAGKGAIINISSSAGLKPTANTAAYSIAKAGLLMLTQIAAMELGP-GIRVNA 179
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
+ PG + T++ +E E + R G+P E+A +AFLASD AS I G
Sbjct: 180 IAPGPLDTDMPHSYLKGHPHKGQIMEHMIERTIVKRLGQPGEIAEVVAFLASDAASYING 239
Query: 240 ASVPVDGG 247
A++ DGG
Sbjct: 240 ATITADGG 247
>UniRef50_A5NTZ6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Rhizobiales|Rep: Short-chain
dehydrogenase/reductase SDR - Methylobacterium sp. 4-46
Length = 252
Score = 110 bits (264), Expect = 4e-23
Identities = 74/249 (29%), Positives = 124/249 (49%), Gaps = 13/249 (5%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKD-CDKFASTLSITAD 61
FAG+ V L++ GA+ L GR +E L+ V+ + + S L + D
Sbjct: 5 FAGQTVVVTGAGTGMGRAAAIRLAREGARSVLVGRRLEPLEAVAAEIAAEGGSALPVACD 64
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLT 120
+ +++E ++++ G++D L NAG++ + T ++ L+ TN+ +
Sbjct: 65 IGNPAEVEAMVRQATRANGRIDGLFANAGVLGAFKPLAETDATDFEELVGTNLLGTFLSI 124
Query: 121 MLAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
++PHL +G + S PG AY +K ++ +ALE P+ VRVN
Sbjct: 125 KHSLPHL---RGGAVVINASWTVNSVMPGAGAYAATKGALIAMMHTLALEQGPRDVRVNS 181
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHA-LGRPGKPDEVAATIAFLASDLASNIT 238
++PG+ILT + + + ++A L HA LGR G PD+VA T+A+L SD A +T
Sbjct: 182 ISPGIILTPMA--DAVLDPAFSAKLA----AHAPLGRNGTPDDVAGTVAWLLSDDARFVT 235
Query: 239 GASVPVDGG 247
G + VDGG
Sbjct: 236 GQDILVDGG 244
>UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Rep:
Dehydrogenase - Flavobacteriales bacterium HTCC2170
Length = 254
Score = 110 bits (264), Expect = 4e-23
Identities = 64/222 (28%), Positives = 117/222 (52%), Gaps = 9/222 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
G ++++ + +K ++ DK + L + D++ ES +E ++K +G++D+LVN
Sbjct: 35 GMKVAILSVGEGSAKKAAESIDKSGTGALGLQCDVSDESSVELALEKINSLFGRIDILVN 94
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR--S 145
+AGI++ +IE + +D++++TN+R + ++ +L +SK R
Sbjct: 95 SAGILDMSSIEEMTTEHWDKVLSTNLRGTFTTIQKSIKYLEKSKFPRIINISSNSGRMGG 154
Query: 146 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 205
F +AY+ SK + T +A +LAPKG+ VNC+ PG I G +S ++ L
Sbjct: 155 FENGMAYSASKGGIIALTYGLARKLAPKGITVNCIAPGTI------EGDMSAQRSQETLN 208
Query: 206 RTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ +GR G P+EVAA + A D + TG+ + V+GG
Sbjct: 209 NLLKRFPIGRFGTPEEVAAAALYYAGDDSGFTTGSVLDVNGG 250
>UniRef50_Q0UWB9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 300
Score = 110 bits (264), Expect = 4e-23
Identities = 66/196 (33%), Positives = 110/196 (56%), Gaps = 9/196 (4%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG-TIENTSLAQYDRLMNTNVR 114
L+I AD T ESD+E +KKT+ +G+LD + NAG + ++ +T+ ++ +M TN R
Sbjct: 106 LTIAADATNESDVEACVKKTVQRFGRLDCALLNAGERDDSKSLFDTTAEDFESIMTTNAR 165
Query: 115 SIYYLTMLAVPHLLESKGXXXXX---XXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
S + L + V +L +G G+R FPG+++Y+ SK ++ A EL
Sbjct: 166 SAF-LGLKHVAKVLRDQGQGGSIILRSSIAGLRGFPGLISYSSSKFALRGIALTAAEELG 224
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
+RVN ++ +I + + G ++E+ L+ K ALGR G+PD+VA +AFLAS
Sbjct: 225 EFDIRVNTIHTSIIDSGPGFKEGWTQER----LDELKGETALGRFGRPDDVANVVAFLAS 280
Query: 232 DLASNITGASVPVDGG 247
+ + +TG + +DGG
Sbjct: 281 EDSKFMTGGHLKIDGG 296
>UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase;
n=4; Xanthobacter autotrophicus Py2|Rep:
2-(R)-hydroxypropyl-CoM dehydrogenase - Xanthobacter sp.
(strain Py2)
Length = 250
Score = 110 bits (264), Expect = 4e-23
Identities = 68/200 (34%), Positives = 103/200 (51%), Gaps = 8/200 (4%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTIENTSLAQYDRLMNTN 112
L + AD+ E D+ I T++ +G +DVLVNNAGI E G + T + Q+D++M N
Sbjct: 55 LRVRADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVN 114
Query: 113 VRSIYYLTMLAVPH-LLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
VR I+ +PH LL+ G + +FPG AY SK +V Q T+ VA++ A
Sbjct: 115 VRGIFLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYA 174
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
G+R N V PG+I T + + E L R + G +VA + FLA
Sbjct: 175 GSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIPQKEI----GTAAQVADAVMFLAG 230
Query: 232 DLASNITGASVPVDGGRHAM 251
+ A+ + GA++ +DG A+
Sbjct: 231 EDATYVNGAALVMDGAYTAI 250
>UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family member
2; n=64; Eumetazoa|Rep: Dehydrogenase/reductase SDR
family member 2 - Homo sapiens (Human)
Length = 258
Score = 110 bits (264), Expect = 4e-23
Identities = 68/224 (30%), Positives = 118/224 (52%), Gaps = 6/224 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 34 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 93
Query: 84 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 94 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 153
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+ YN+SK ++ TR +ALELAPK +RVNCV PG+I T+ + +E +
Sbjct: 154 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 213
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDG 246
F KE H L R G+ ++ A ++FL S AS + G ++ V G
Sbjct: 214 F----KEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAG 253
>UniRef50_UPI0000DAE1BB Cluster: oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Coxiella burnetii
Dugway 7E9-12|Rep: oxidoreductase, short chain
dehydrogenase/reductase family - Coxiella burnetii
Dugway 7E9-12
Length = 258
Score = 109 bits (263), Expect = 5e-23
Identities = 68/219 (31%), Positives = 114/219 (52%), Gaps = 7/219 (3%)
Query: 38 NVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 96
+ EN +KV + A L I AD+TK D ++II +TI+ + +++VLVNNAGI
Sbjct: 42 DAENARKVEAALSDYPAQLLLIKADITKAEDRQRIIDETINTFQRINVLVNNAGIPAKAG 101
Query: 97 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXXXXGIRSFPGVLAYNI 154
+ ++R+++ N+++ +L L +++ G G R+ G+ +Y+
Sbjct: 102 FLKEAEEDFNRVIDVNLKAPIFLAKLVAEQMIKQAQGGSIINFSSVAGHRAMGGI-SYDA 160
Query: 155 SKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALG 214
+KA + + ++ +A L G+RVN ++PG TE+ R E E AL
Sbjct: 161 AKAGIIRASQTMANTLGKYGIRVNSISPGTHKTEMNR---YQWENRTELYENMIAVTALK 217
Query: 215 RPGKPDEVAATIAFLASDLASNITGASVPVDGGRHAMCP 253
R + DE+A T+ +LASD +S TG + VDGG + CP
Sbjct: 218 RAAEADEMAGTVLYLASDQSSYTTGTDILVDGGYLSHCP 256
>UniRef50_Q987X7 Cluster: Probable short-chain dehydrogenase; n=1;
Mesorhizobium loti|Rep: Probable short-chain
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 261
Score = 109 bits (263), Expect = 5e-23
Identities = 66/200 (33%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Query: 53 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 112
A L T D++ + + + +G +DV+VN+A + GT T ++R M+ N
Sbjct: 54 ADALVQTVDVSISDQVRDAVVAGVAKFGGIDVIVNSAAVHPYGTATTTDWETWNRAMSVN 113
Query: 113 VRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
V SIY +P +++ G G V AY +K ++ TR +AL+ A
Sbjct: 114 VGSIYLTAHFGIPEMIKRGGGAIVNVASVQGFACQQNVAAYATTKGAIHTLTRSLALDYA 173
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE----RTKETHALGRPGKPDEVAATIA 227
G+RVN V+PG I T + + + A +E R H LGR G+P+EVA IA
Sbjct: 174 AAGIRVNSVSPGSIRTPILEKAARGDHGSDADVEEAYKRFGAAHPLGRIGEPEEVAEFIA 233
Query: 228 FLASDLASNITGASVPVDGG 247
FL S AS TGA +DGG
Sbjct: 234 FLCSSKASFCTGADYKIDGG 253
>UniRef50_Q67QU0 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=1; Symbiobacterium thermophilum|Rep:
3-oxoacyl-(Acyl-carrier protein) reductase -
Symbiobacterium thermophilum
Length = 238
Score = 109 bits (263), Expect = 5e-23
Identities = 66/191 (34%), Positives = 101/191 (52%), Gaps = 7/191 (3%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
+ D+ + E + T+D +G++D+LVNNAG + +T+ A+++ L+ ++ +Y
Sbjct: 51 LQVDVRDPAACEAAVSGTVDRFGRIDILVNNAGTALEKLLVDTTPAEWNDLVAVHLTGMY 110
Query: 118 YLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
T A+PH+L + G GI G +AY+ KA + FTR +A E+ P GV
Sbjct: 111 ACTRAALPHMLSRRYGRIITISSIWGITGAAGEVAYSAVKAGQNGFTRALAQEVGPFGVT 170
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
VN V PG I TE+ L E+ +L R +GR G P+EVAA + FLA A
Sbjct: 171 VNAVAPGAIDTEM--NSFLQGEELREWLSRV----PVGRLGTPEEVAALVRFLAGPQAGF 224
Query: 237 ITGASVPVDGG 247
ITG + +GG
Sbjct: 225 ITGQVISPNGG 235
>UniRef50_Q5P686 Cluster: Subunit of
2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH; n=4;
Proteobacteria|Rep: Subunit of
2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH - Azoarcus sp.
(strain EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 248
Score = 109 bits (263), Expect = 5e-23
Identities = 64/210 (30%), Positives = 109/210 (51%), Gaps = 10/210 (4%)
Query: 43 QKVSKDCDKFAS----TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIE 98
+KV D+F+ L AD++ ++ ++ ++++T++ +G++D+LVNNAG+ G +
Sbjct: 40 EKVRTTVDEFSRLGHRVLGTVADISNKAAVDGMVQQTVEAFGRIDILVNNAGMERAGALR 99
Query: 99 NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKAS 158
S A +D ++ N++ + T H++E+K G Y+ +KA
Sbjct: 100 KLSEADWDITVDVNLKGTFLCTQAVHGHMVENKHGRIVNIASRAWLGGAGQTPYSSAKAG 159
Query: 159 VDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGK 218
V TR +A+EL G+ VNCV PG+I T + L E+ L R G+ G+
Sbjct: 160 VVGMTRALAIELGRSGITVNCVAPGLIHTPMWEE--LPEKDRNFLLSR----QPTGKLGE 213
Query: 219 PDEVAATIAFLASDLASNITGASVPVDGGR 248
PD++A T+ FLA D +TG + V GGR
Sbjct: 214 PDDIANTLLFLADDDTGFVTGQVLYVCGGR 243
>UniRef50_A0VT49 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Dinoroseobacter shibae DFL
12
Length = 256
Score = 109 bits (263), Expect = 5e-23
Identities = 75/225 (33%), Positives = 122/225 (54%), Gaps = 11/225 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++++ N E + V+ + A +++T D++K +D+ + +++TID +G++D+ +NN
Sbjct: 36 GARVAIVDLNGEGAKAVADALQQNA--IAVTCDVSKGADVSRAVQETIDAFGRVDIAINN 93
Query: 89 AGIIETG-TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSF 146
AG + + R+ NV SI++ T VPH + G GIR
Sbjct: 94 AGWSHRNQPALDVDFETFKRVYEVNVDSIFHATHALVPHWRDIGGGVMINVGSTAGIRPR 153
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE-LQRRGGLSE--EQYAAF 203
PG+ YN SK +V+ T+ +A+ELAP VRV + P + T L+ G+ + E A F
Sbjct: 154 PGLSWYNSSKGAVNMMTKTLAVELAPDRVRVCGLAPVMGATPLLETFMGMPDTPENRAKF 213
Query: 204 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
L T LGR +P+++A +LASD A+ ITG + VDGGR
Sbjct: 214 L----GTIPLGRLCEPEDMANAALYLASDEANFITGVILEVDGGR 254
>UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member
10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR
family member 10 - Homo sapiens (Human)
Length = 270
Score = 109 bits (263), Expect = 5e-23
Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 5/246 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
+AGKVV GA++ + ++ + + ++ + I D+
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE---LPGAVFILCDV 63
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTM 121
T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Y LT
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 122 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVRVNC++
Sbjct: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG I T L A + LGR G+P EV A FLAS+ A+ TG
Sbjct: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIE 242
Query: 242 VPVDGG 247
+ V GG
Sbjct: 243 LLVTGG 248
>UniRef50_Q5V8A5 Cluster: LtxD; n=2; Bacteria|Rep: LtxD - Lyngbya
majuscula
Length = 246
Score = 109 bits (262), Expect = 7e-23
Identities = 65/191 (34%), Positives = 104/191 (54%), Gaps = 6/191 (3%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 116
++ DL + +DIE++ + T + +LD+LVN+A ++TG+IE+ S+ + R+ N +
Sbjct: 60 AMAVDLAQPADIERLFEMTEATWQRLDILVNSAAELQTGSIESFSIHDWQRVFAVN-STA 118
Query: 117 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
+LT+ L + G + + PG+ AY SK S++Q TR A ELA +G+
Sbjct: 119 PFLTIQQAARRLSAHGRIVNVSTINTVLAEPGIAAYAASKGSLEQLTRVAAWELADRGIT 178
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
VN V+PG T+L R G E LE+ LGR G+P ++A +AFL +
Sbjct: 179 VNSVSPGPTDTDLLRTGNPPE-----VLEQAIAMTPLGRLGQPKDIADVVAFLVGNDGRW 233
Query: 237 ITGASVPVDGG 247
ITG ++ V GG
Sbjct: 234 ITGQNLRVTGG 244
>UniRef50_Q0RL77 Cluster: Putative Short chain dehydrogenase; n=1;
Frankia alni ACN14a|Rep: Putative Short chain
dehydrogenase - Frankia alni (strain ACN14a)
Length = 263
Score = 109 bits (262), Expect = 7e-23
Identities = 71/226 (31%), Positives = 109/226 (48%), Gaps = 6/226 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKLD 83
L GA++++ R L V+ D A+ ++I+ADLT E D+ ++ + +D G +D
Sbjct: 30 LDAAGARVAVVARGGAGLAAVA---DGLANKPVTISADLTVEDDVRRVADQALDELGDVD 86
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 143
+LVNNAG+ E + D +N N+R++ LT P LL +G
Sbjct: 87 ILVNNAGLGWHQPPEAITAKPLDLQLNLNLRNVILLTSWLAPSLLRRRGCVVTMSSAAAY 146
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR--GGLSEEQYA 201
Y +K ++ T+ +A +GVRVN V PG + T++ + L EE Y
Sbjct: 147 GGDVEQAVYAATKGGLNTLTQNLATAWGDRGVRVNAVAPGFVDTDIWQPLIAALGEEGYQ 206
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
F T L R DE+A + FL SD AS +TG ++ VDGG
Sbjct: 207 RFRRATAAGIPLRRWASADEIATVVLFLCSDAASYLTGQTLVVDGG 252
>UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp.
HTCC2601|Rep: FabG3_1 - Roseovarius sp. HTCC2601
Length = 249
Score = 109 bits (262), Expect = 7e-23
Identities = 75/255 (29%), Positives = 124/255 (48%), Gaps = 15/255 (5%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
M+ GKVV ++ GA + L + ++ +++D A L++
Sbjct: 1 MDVTGKVVLISGAARGMGAHEARRFAEAGACVILGDVLDDEVRALAEDLGD-ARALAVPL 59
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+++ D E + + +G++DVLVNNAGI+ IE S +++++++ N+ +
Sbjct: 60 DVSRSEDWEGAVAAGVARFGQIDVLVNNAGILRFSNIETCSDEEWEKVLSINLGGAFKGI 119
Query: 121 MLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+P + + G G+++F GV AY SK + TR A+ELA G+RVN
Sbjct: 120 RAVLPVMKRNGSGSIINISSTAGLKAFGGVSAYVTSKFGIRGLTRAAAVELAGHGIRVNS 179
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHA-LGRPGKPDEVAATIAFLASDLASNIT 238
V+PG I T+ + E+ Y F H + R G+PDE+A + +LASD +S T
Sbjct: 180 VHPGNIDTD------MVEDLYPNF------NHVPMKRMGQPDEIANLVIYLASDASSFST 227
Query: 239 GASVPVDGGRHAMCP 253
GA DGG P
Sbjct: 228 GAEFVADGGETGGMP 242
>UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Glucose-1-dehydrogenase -
Lentisphaera araneosa HTCC2155
Length = 264
Score = 109 bits (262), Expect = 7e-23
Identities = 55/197 (27%), Positives = 106/197 (53%), Gaps = 2/197 (1%)
Query: 53 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 112
++ L++ D+ + + +I K I+ +G++D +VNNAGI T+ +D+++NTN
Sbjct: 51 SNALAVACDVCSDEAQQNVIDKAIEKWGRVDCIVNNAGINFAKPFLETTKQDWDKVLNTN 110
Query: 113 VRSIYYLTMLAVPHLL--ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL 170
+R++++ + + ++KG + PG Y +K + +C EL
Sbjct: 111 LRAVFFFMQKLCKYWIDNQTKGSIVNISSVHNQATLPGAGPYAATKNGLLGIMKCAVNEL 170
Query: 171 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 230
+ KG+RVN V+PG+ T + + + L+ K+ +GRP +P+E+ T++FL
Sbjct: 171 SSKGIRVNTVSPGLCNTNIWQDIIEAAPNEKECLDYWKQQIPIGRPSEPEEIGYTVSFLL 230
Query: 231 SDLASNITGASVPVDGG 247
SD +S+ TG ++ +DGG
Sbjct: 231 SDRSSSTTGTNIYLDGG 247
>UniRef50_A0Z5T7 Cluster: 3-ketoacyl-(Acyl-carrier-protein)
reductase; n=2; unclassified Gammaproteobacteria
(miscellaneous)|Rep: 3-ketoacyl-(Acyl-carrier-protein)
reductase - marine gamma proteobacterium HTCC2080
Length = 248
Score = 109 bits (262), Expect = 7e-23
Identities = 63/192 (32%), Positives = 106/192 (55%), Gaps = 9/192 (4%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
++I AD++ + + + +TI +G++DV+VNNAG+ G +E S + ++N N+
Sbjct: 56 IAIQADVSDVAAAQSAVDETIATFGRIDVVVNNAGVHRGGKVERLSPEDWQTVLNVNLTG 115
Query: 116 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 175
+ A PH+ S G R FPG +AY SKA + T +A+E+A +G+
Sbjct: 116 ALNMIRAAKPHM-GSGSSIINIGAVVGFRGFPGDVAYASSKAGLSGMTNALAIEMAKQGI 174
Query: 176 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
VN V PG++LT++ GL++ A ++ K +GR G+ EVA + ++ +
Sbjct: 175 TVNLVIPGLVLTDM--TSGLTD----AAMDNMKAKIPMGRLGQDREVAEVVYWVTQ--SR 226
Query: 236 NITGASVPVDGG 247
+TGA+VPVDGG
Sbjct: 227 YMTGATVPVDGG 238
>UniRef50_A0GDY0 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=5; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Burkholderia
phytofirmans PsJN
Length = 249
Score = 109 bits (262), Expect = 7e-23
Identities = 67/219 (30%), Positives = 108/219 (49%), Gaps = 3/219 (1%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA + + GR + + + A+ L T DL + +++ + +G LD+ V N
Sbjct: 30 GAHVLIVGRRLAAVNAAVAELGDRATGL--TGDLADPATHDRVASLVEERFGGLDIYVAN 87
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 148
AG+ SL +YD + TN RS+++ + V L + G + F G
Sbjct: 88 AGVNTIARSHLVSLEEYDAQVATNTRSVFF-GVQKVASQLRNGGAILLTSSIASSKVFEG 146
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 208
AY SKA+++ F R ALE +G+RVN ++PG + T + + G++ AF
Sbjct: 147 HAAYAGSKAAIEAFARSWALEFKERGIRVNVISPGPVDTPILSKLGIAVADRPAFEAAVA 206
Query: 209 ETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E LGR G+ +E+A FL SD +S +TG ++ VDGG
Sbjct: 207 EKIPLGRLGRAEELAQAALFLVSDESSFVTGVNLHVDGG 245
>UniRef50_A0GDT9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Burkholderia phytofirmans PsJN
Length = 252
Score = 109 bits (262), Expect = 7e-23
Identities = 62/197 (31%), Positives = 107/197 (54%), Gaps = 10/197 (5%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTS-LAQYDRLMNTNVR 114
+++ AD ++ +I + I+ G++D+LVNNA + TGT+ T+ + ++R + N
Sbjct: 64 IALKADQADAKAVKALIAEVIERLGRIDILVNNAAVFVTGTVAETADTSAFERQVKINYE 123
Query: 115 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPK 173
++ + +++S G RS +PG+ Y+ +K +++ +++ A +L PK
Sbjct: 124 AVV-TAIREASRVMDSGGRIISISSALAWRSTWPGLADYSATKRAIEGYSKGAARDLGPK 182
Query: 174 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 233
G+ VN + G TE+ + F E ALGR G+P+E+A+ IAF+AS
Sbjct: 183 GITVNVIGTGSTNTEMN-------PDDSPFAEAQAAATALGRFGRPEEIASVIAFVASPA 235
Query: 234 ASNITGASVPVDGGRHA 250
AS ITGA +PVDGG A
Sbjct: 236 ASFITGAIIPVDGGYSA 252
>UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=26; Bacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 248
Score = 109 bits (262), Expect = 7e-23
Identities = 66/221 (29%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSIT-ADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA + + G N E Q V + +S D++ ++ ++K +D + K+D+LVN
Sbjct: 31 GADVEIWGLNEERGQAVIESLTGLGGEVSFARVDVSHNGGVKDCVQKFLDKHNKIDILVN 90
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 146
NAGI + S + +++TN+ S+YY + H+++++ G
Sbjct: 91 NAGITRDNLLMRMSEDDWQSVISTNLTSLYYTCSSVIRHMIKARSGSIINVASIVAKIGS 150
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 206
G Y +KA + FT+ +A E+A + +RVNC+ PG I T++ L++ A +L
Sbjct: 151 AGQTNYAAAKAGIIAFTKSLAKEVAARNIRVNCLAPGFIETDM--TSVLNDNLKAEWL-- 206
Query: 207 TKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
++ LGR G P++VA FLAS L+S +T ++ VDGG
Sbjct: 207 --KSIPLGRAGTPEDVARVALFLASQLSSYMTAQTLVVDGG 245
>UniRef50_Q39MZ9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Burkholderia sp. 383|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 249
Score = 109 bits (261), Expect = 9e-23
Identities = 67/190 (35%), Positives = 95/190 (50%), Gaps = 3/190 (1%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
+ DLT++ K+I I+ +G+LD LVNNAG+ E TS Y R + NV S+
Sbjct: 50 VDVDLTQDDAAAKVIAACIERHGRLDSLVNNAGLGNAKPFEQTSPEDYQRYYDINVGSLL 109
Query: 118 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
L A+PHL S+G G+ AY +K +V TR +A E G+RV
Sbjct: 110 ALCGSALPHLKASRGSIVNIASAFGLVGVAQAAAYVPTKYAVVGMTRMLATEFGCHGIRV 169
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
N V PG++ + + S + + E LGR G+P+E+ FL+S AS I
Sbjct: 170 NAVAPGLVRSPGTEQRIASNPWWHKMM---IEGAPLGRVGEPEEIGHACRFLSSPQASFI 226
Query: 238 TGASVPVDGG 247
TG +PVDGG
Sbjct: 227 TGVVLPVDGG 236
>UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC
16129)
Length = 256
Score = 109 bits (261), Expect = 9e-23
Identities = 60/199 (30%), Positives = 108/199 (54%), Gaps = 12/199 (6%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-------IETGTIENTSLAQYDRLM 109
++ D+++E D+ +++ D YG+LDVL NNAG+ ++ ++ T +D ++
Sbjct: 58 AVKVDVSREPDVRAMVESATDRYGRLDVLFNNAGVGYSASGRMKMASVVETPEKDWDAIL 117
Query: 110 NTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 168
N++ + A+P + + G + PG AY +K V F+R +A+
Sbjct: 118 AINLKGVALGCKHAIPVMERQGYGSIINNASINALVGLPGADAYTAAKGGVVAFSRVLAV 177
Query: 169 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAF 228
E P+G+RVNC+ PG + T + +S+E+ ++ ++ LGR +P+E+A+ F
Sbjct: 178 EWGPRGIRVNCICPGGVDTPM-IAPVISDER---VMQSMRQNTPLGRLARPEEIASVALF 233
Query: 229 LASDLASNITGASVPVDGG 247
LAS+ AS + GA +PVDGG
Sbjct: 234 LASEEASYLNGAIIPVDGG 252
>UniRef50_A6T0X0 Cluster: Glucose-1-dehydrogenase, (3-oxoacyl-(Acyl
carrier protein) reductase); n=4; Proteobacteria|Rep:
Glucose-1-dehydrogenase, (3-oxoacyl-(Acyl carrier
protein) reductase) - Janthinobacterium sp. (strain
Marseille) (Minibacterium massiliensis)
Length = 258
Score = 109 bits (261), Expect = 9e-23
Identities = 71/250 (28%), Positives = 117/250 (46%), Gaps = 5/250 (2%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA- 60
+F+ KV L K GA + + GR+ LQ+V+ + D + A
Sbjct: 3 SFSSKVAIVTGGGSGIGKEVAARLVKAGANVVIGGRDAAKLQRVATEIDPSGDHVRFHAG 62
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+ + + ++ +G +D+L+NNAG+ A+YD ++T ++ +++
Sbjct: 63 DIAQPATATALVDLAKQAFGGVDILINNAGVFRPKAFLEVEEAEYDWFLDTILKGKFFMA 122
Query: 121 MLAVPHL-LESKGXXXXXXXXXGIRSFPGV--LAYNISKASVDQFTRCVALELAPKGVRV 177
A + L G +++ AY+ + A V TR +A+ELA +R+
Sbjct: 123 QAAAKAMKLRGGGAIVQTGSLWALQAIGATPSAAYSAANAGVHALTRNLAIELAASNIRI 182
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
N V PGV+ T + ++++Q A L H LGR G+P +VA I FLAS AS I
Sbjct: 183 NTVAPGVVETPVYNTF-MTDDQVKATLPAFNAFHPLGRNGQPADVAEAILFLASANASWI 241
Query: 238 TGASVPVDGG 247
TG + VDGG
Sbjct: 242 TGTVLSVDGG 251
>UniRef50_A4XF86 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Novosphingobium aromaticivorans DSM
12444|Rep: Short-chain dehydrogenase/reductase SDR
precursor - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 253
Score = 109 bits (261), Expect = 9e-23
Identities = 65/183 (35%), Positives = 94/183 (51%), Gaps = 6/183 (3%)
Query: 71 IIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES 130
++ + ++ G +D+L+N AGI+ G E TS + R M+ N+ ++L ++PHL S
Sbjct: 69 LVTEAVEVLGGIDILLNVAGIMTWGRFEETSPQAWQRTMDINLSGPFFLIQASIPHLKAS 128
Query: 131 KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 190
KG G+ G AY +SKA V T+ ALE A GVR N V PG + T +
Sbjct: 129 KGNVVSVASAGGLHPVYGTSAYGVSKAGVIAITQSAALEFARFGVRANAVAPGGVATPMH 188
Query: 191 RR----GGLSEEQYAAFLERTKETHALGRPG-KPDEVAATIAFLASDLASNITGASVPVD 245
+ GG+ +A R RP P+EVAA IA+LASD A TG + +D
Sbjct: 189 EKSSAGGGVDPAIFAEAAGRNM-PKLTDRPACTPEEVAAAIAYLASDEARYATGTVLVLD 247
Query: 246 GGR 248
GG+
Sbjct: 248 GGQ 250
>UniRef50_A3WFK2 Cluster: Glucose dehydrogenase; n=1; Erythrobacter
sp. NAP1|Rep: Glucose dehydrogenase - Erythrobacter sp.
NAP1
Length = 255
Score = 109 bits (261), Expect = 9e-23
Identities = 68/219 (31%), Positives = 99/219 (45%), Gaps = 3/219 (1%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++ +TGR + + + A AD T SD++ + D +G++D+L N
Sbjct: 36 GAEVIITGRKQKGIDAALAELG--AGAHGFVADSTSISDLQALADFAKDTFGEVDILFAN 93
Query: 89 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 148
AG I+ Y R + NV+ ++ +P +L + PG
Sbjct: 94 AGNGMFAPIDQVDEELYARQFDLNVKGAFFTVQAFLP-VLSGNSSVIITSSAVHAKGAPG 152
Query: 149 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 208
Y SKA+V F R +A EL +GVRVN ++PG++ T E Y F
Sbjct: 153 GTLYFASKAAVRSFARTMAAELGGRGVRVNTLSPGIVPTNFFENSNAPTELYHDFEAMAG 212
Query: 209 ETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ LGR GKP E+A FLASD AS +T A DGG
Sbjct: 213 QGAPLGRAGKPVEIAEVAVFLASDEASFVTAADYVADGG 251
>UniRef50_A1WWM8 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Halorhodospira halophila SL1|Rep: Short-chain
dehydrogenase/reductase SDR - Halorhodospira halophila
(strain DSM 244 / SL1) (Ectothiorhodospirahalophila
(strain DSM 244 / SL1))
Length = 254
Score = 109 bits (261), Expect = 9e-23
Identities = 81/259 (31%), Positives = 126/259 (48%), Gaps = 15/259 (5%)
Query: 1 MNFA-GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 59
MN A G+V+ L GA+L LT R E +Q+++++ A+ +++
Sbjct: 1 MNRAQGRVIVITGAAGGIGEATARHLHAQGARLLLTDREPEGVQRLAEELGDGAAAMAV- 59
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYY 118
D++ ++D E +I++ +G + L NAGI + G +E+ + ++++ NV + Y
Sbjct: 60 -DVSSQADNEAMIQEAEARFGAVHGLFLNAGIEGQAGPLEDADDSVWNQVFAVNVHGVRY 118
Query: 119 LTMLAVPHLLESKGXXXXXXXX-XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
A+P L ++G G+R G+ Y SK +V R A EL P+G+RV
Sbjct: 119 GIQAALPALRRAQGGSILITASVAGVRGAAGLSPYVSSKHAVMGLMRTAAAELGPEGIRV 178
Query: 178 NCVNPGVILTELQR------RGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
N VNPG + + R G +E F R LGR DEVAA AFL S
Sbjct: 179 NTVNPGPVDNRMMRSIEDQVSPGHGDEVKRGFTARI----PLGRYVNNDEVAAVAAFLLS 234
Query: 232 DLASNITGASVPVDGGRHA 250
+ AS ITG++ VDGG A
Sbjct: 235 EAASGITGSNYMVDGGMTA 253
>UniRef50_A1W5S4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=30; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Acidovorax sp. (strain
JS42)
Length = 257
Score = 109 bits (261), Expect = 9e-23
Identities = 69/250 (27%), Positives = 119/250 (47%), Gaps = 8/250 (3%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
F+GK + + G + + G E ++ K+ ++TA+L
Sbjct: 5 FSGKKLLVVGGTSGMGKETARLVLAQGGNVVIVGNRPEKTEEARKELAALGQVSALTANL 64
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
TK+ D+ ++K + + +D+LVN AG+ S A YD+ M N ++ +++T
Sbjct: 65 TKDEDVAALLKAIDEQHPDIDLLVNAAGVFFPKPFLEHSDADYDQYMKLN-KAFFFITQ- 122
Query: 123 AVPHLLESKGXXXXXXXXXGIRSFPGVL-----AYNISKASVDQFTRCVALELAPKGVRV 177
V L +KG + + + AY+++KA + T+ +A+ELAPK +RV
Sbjct: 123 KVAGNLAAKGKPGAIVNIGSMWAKQAIAATPSSAYSMAKAGLHSLTQHLAMELAPKHIRV 182
Query: 178 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
N V+P V+ T + G + + + ++ H +GR G P +VA + FL SD A +
Sbjct: 183 NAVSPAVVETPIY-EGFIPKAEVHGAMQGFNSFHPIGRVGTPQDVAEAVVFLLSDKAGWV 241
Query: 238 TGASVPVDGG 247
TGA VDGG
Sbjct: 242 TGAIWDVDGG 251
>UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2;
Gammaproteobacteria|Rep: Short chain dehydrogenase -
marine gamma proteobacterium HTCC2143
Length = 259
Score = 109 bits (261), Expect = 9e-23
Identities = 64/202 (31%), Positives = 105/202 (51%), Gaps = 5/202 (2%)
Query: 54 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTN 112
+ + + D+TKESD++ +I+ T YG +D NNAGI IE G + + ++D +M N
Sbjct: 57 NAIFVPCDVTKESDVQWLIETTCSTYGSVDYAFNNAGIDIEKGELSKGTEDEFDSIMAVN 116
Query: 113 VRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
V+ ++ + ++ + G G+ + P + Y SK +V T+ A+E A
Sbjct: 117 VKGVWLCMKHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVENA 176
Query: 172 PKGVRVNCVNPGVILTELQRRGGL---SEEQYAAFLERTKETHALGRPGKPDEVAATIAF 228
G+R+N V PGVI T + R + SE + R H + R G +E++ + +
Sbjct: 177 RNGIRINAVCPGVIDTNMFNRSRMFDRSEVSASETRARVNAIHPMDRIGTAEEISDAVLY 236
Query: 229 LASDLASNITGASVPVDGGRHA 250
L SD AS ITG ++ VDGG +A
Sbjct: 237 LCSDGASFITGHTLSVDGGLNA 258
>UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
2-deoxy-D-gluconate 3-dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 254
Score = 109 bits (261), Expect = 9e-23
Identities = 67/249 (26%), Positives = 117/249 (46%), Gaps = 6/249 (2%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITA 60
N GKV L GA +++ R L+ D L+ +
Sbjct: 7 NLEGKVAIVTGAGRGLGRAMAKGLVDAGAAVTVAARTSAELESFVADAKAAGGQALACST 66
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+T E+ +E+++ T++ +G++D+LVNN+GI+ T + S ++DR++ TN+R + T
Sbjct: 67 DITDEASVERLVDATVETFGRVDILVNNSGIVATTPLIEQSADEWDRVVATNLRGTFLAT 126
Query: 121 MLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
HL+ + G ++ AY+ SKA V FTR +A+E A ++VN
Sbjct: 127 RAVGRHLVAQRSGKVINIASNFALQGVANHAAYSASKAGVIAFTRSMAIEWARDNIQVNA 186
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
+ PG T L ++ AA + R R G+P+E+ + + LA + +TG
Sbjct: 187 IAPGYFATSL-NADMRADADMAAKVVRAIPAR---RMGEPEELTSWLLLLAGSASDFMTG 242
Query: 240 ASVPVDGGR 248
+ +DGG+
Sbjct: 243 EVIVIDGGQ 251
>UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6;
Pseudomonas aeruginosa|Rep: Probable short-chain
dehydrogenase - Pseudomonas aeruginosa
Length = 252
Score = 108 bits (260), Expect = 1e-22
Identities = 63/196 (32%), Positives = 103/196 (52%), Gaps = 5/196 (2%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
ADL + ++ K + G+LD LVN AG+ G +EN + +D ++ N+++ +Y+
Sbjct: 55 ADLRSADNCHTLMSKILARTGRLDALVNAAGVWREGPVENFTEEDFDLVLGVNLKASFYM 114
Query: 120 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
A+P+L E++G G +++ G AY SKA++ ++ +ALELA +GVRVN
Sbjct: 115 CQAAIPYLKENQGSIVNISSDSGRQAYRGSAAYCASKAALTMLSKTLALELAEQGVRVNA 174
Query: 180 VNPGVILT-----ELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
V+P I T + +R G + + Y L + R +P+EVA + +L A
Sbjct: 175 VSPADIATPMLDYQAERYGMGNPDGYKRALLKDYPQGKAARFIRPEEVAELVWYLCGPQA 234
Query: 235 SNITGASVPVDGGRHA 250
ITGA + VD G A
Sbjct: 235 EAITGADLAVDFGLSA 250
>UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep:
Oxidoreductase - Oceanobacillus iheyensis
Length = 244
Score = 108 bits (260), Expect = 1e-22
Identities = 73/249 (29%), Positives = 113/249 (45%), Gaps = 11/249 (4%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 59
M KV + GA+L L N E + + S + I
Sbjct: 1 MKLQDKVAVITGGVSGIGAATAKLFASEGAKLILVDMNEEKGASIEAELKSQGSEAIFIK 60
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
AD+T E ++ I ID +GK+D+L NNAGI E + A++ + + ++ ++ +
Sbjct: 61 ADVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVFLV 120
Query: 120 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
A+ L++ G G PG AYN +KA V TR + LE A + +RVN
Sbjct: 121 AQAAIKEFLKAGSGVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGLEYAARNIRVN 180
Query: 179 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
+ PG I T + L + A + T + R GK +E+A + F+ASD +S +T
Sbjct: 181 ALCPGFIDTAI-----LGDSDREALINTT----PMNRLGKSEEMAKAVLFMASDDSSFMT 231
Query: 239 GASVPVDGG 247
G S+ VDGG
Sbjct: 232 GNSLIVDGG 240
>UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Geobacter metallireducens GS-15|Rep: Short-chain
dehydrogenase/reductase SDR - Geobacter metallireducens
(strain GS-15 / ATCC 53774 / DSM 7210)
Length = 257
Score = 108 bits (260), Expect = 1e-22
Identities = 69/228 (30%), Positives = 120/228 (52%), Gaps = 11/228 (4%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 84
++ GA L L RN+E + + + K ++ D+ ++ +++ ++ T++ +GK+D+
Sbjct: 32 AEAGASLVLCSRNLEQCEDAAANIRKLGVECDALRCDIGEQDEVKAVVAHTMNRFGKIDI 91
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXXGI 143
LVNNAGI G +++T L ++D+L +TNVR Y+ T V P + G G+
Sbjct: 92 LVNNAGISWGGELQDTPLKKWDQLYSTNVRGNYFFTTEVVSPMIAGGGGNIINIVSIGGV 151
Query: 144 RSF-PGVL---AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 199
RS P V+ AY +K ++ T+ ++ A +RVN + PG+ TE+ + L
Sbjct: 152 RSTDPKVVTFPAYASTKGAIIALTKHLSRNWAKHNIRVNAIAPGIFPTEISKT--LMVGP 209
Query: 200 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
A +E LGR G+ D+ FLA+D + +TG+ + VDGG
Sbjct: 210 QKAVMEAAV---PLGRLGEKDDFKGAALFLAADASRYVTGSVLWVDGG 254
>UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 262
Score = 108 bits (260), Expect = 1e-22
Identities = 63/191 (32%), Positives = 100/191 (52%), Gaps = 5/191 (2%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+T E+D+ ++ + + H+G+LDVLVNNAGI +LAQ+ R+++ NV ++
Sbjct: 69 DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128
Query: 120 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
T A+PH+ G GI P V AY+ SKA+V + A+ A K +R N
Sbjct: 129 TRAAIPHIDAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAVRMMAKVDAMLYAAKNIRAN 188
Query: 179 CVNPGVILTELQRRG--GLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
V+PG I T + + ++ AF E + + + G P ++AA I +L S
Sbjct: 189 SVHPGYIRTPMLEDAFRQMGQDPDRAF-EYMQTNVPMAKIGSPRDIAAGILYLVSPAGRY 247
Query: 237 ITGASVPVDGG 247
+TGA + +DGG
Sbjct: 248 VTGAELVIDGG 258
>UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like
protein; n=1; Hahella chejuensis KCTC 2396|Rep:
Short-chain alcohol dehydrogenase-like protein - Hahella
chejuensis (strain KCTC 2396)
Length = 251
Score = 108 bits (260), Expect = 1e-22
Identities = 74/251 (29%), Positives = 119/251 (47%), Gaps = 8/251 (3%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNV-ENLQKVSKDCDKFASTLSIT 59
M GKVV L+ GA++++ R E+ V + +SI
Sbjct: 1 MKLDGKVVMVTGASSGIGRTTAIKLANYGAKVAVIARRSRESEDTVRHITEAGGQAISIP 60
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYY 118
AD++ ESDI+ + + I+ +GKLD NNAG E G + S ++DR+ + N + +
Sbjct: 61 ADVSSESDIKNALAQIIETFGKLDGAFNNAGAAEPVGPLTELSEQEWDRVFSINTKGAWL 120
Query: 119 LTMLAVPHLLESK-GXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
+P LL +K G G + + G+ AY SK ++ T+ +LE A + +R
Sbjct: 121 CMKHQIPALLSNKSGAIVNMSSIYGLVGTGMGLAAYVASKHAIIGLTKAASLEYAARNIR 180
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
+N + PG I T + LS + AF + H GR G EVA + ++ SD AS
Sbjct: 181 INAICPGWIPTPGNEQ-ALSNPEVMAF---AQSLHPQGRLGTQQEVAEAVCWMLSDSASY 236
Query: 237 ITGASVPVDGG 247
+ G ++ +DGG
Sbjct: 237 LNGQTISIDGG 247
>UniRef50_Q9EX74 Cluster: SDR-like enzyme; n=1; Rhodococcus
erythropolis|Rep: SDR-like enzyme - Rhodococcus
erythropolis
Length = 246
Score = 108 bits (260), Expect = 1e-22
Identities = 70/225 (31%), Positives = 115/225 (51%), Gaps = 11/225 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
L LGA + + +N V+K+ A +++ D+ + D E++++ + H+G LD+
Sbjct: 27 LCALGASVVVADIVFDNATLVAKEFGDRA--VAVEVDVARVEDAERMVETAVAHFGGLDI 84
Query: 85 LVNNAGI--IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
VNNAG+ ++ +T ++ R+++ N+ ++ M A + G G
Sbjct: 85 AVNNAGVGVPVKASVGDTGFEEWRRVLDVNLDGAFFC-MRAELRRMRKGGSVVNLASVMG 143
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+ G +Y SK ++ T+ AL+ A G+RVN V G + T L G E AA
Sbjct: 144 AVAAEGSSSYVASKHALVGLTKTAALDYATAGIRVNAVGAGFVDTPLM--AGRDPEWLAA 201
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+H LGR +PDE+A+ +AFLAS AS +TGA +PVDGG
Sbjct: 202 ----VAASHPLGRLAQPDEIASVVAFLASSAASFVTGAFIPVDGG 242
>UniRef50_Q2CH74 Cluster: Short-chain alcohol dehydrogenase; n=1;
Oceanicola granulosus HTCC2516|Rep: Short-chain alcohol
dehydrogenase - Oceanicola granulosus HTCC2516
Length = 245
Score = 108 bits (260), Expect = 1e-22
Identities = 74/252 (29%), Positives = 118/252 (46%), Gaps = 12/252 (4%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITAD 61
+ AGK + ++ GA L L R+ C L++ D
Sbjct: 4 DLAGKCILVTGAGDGIGRAAARLFAEAGAHLVLVDRHGAQAT-ADAHCP---GALAVEMD 59
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG-TIENTSLAQYDRLMNTNVRSIYYLT 120
+ + ++++ + +G +D LVNNAGI G T+ + S +D +++ N + ++
Sbjct: 60 VRDGAGWDRLVAEATARFGGIDALVNNAGIAVPGDTVTDASEEMWDDILDINAKGVWLGM 119
Query: 121 MLAVPHLLESKGXXXXXXXXXGIR-SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+P ++E G PG AY SK +V TR ++ AP G+++N
Sbjct: 120 RAVLPGMVERGGGHICNVASTAAHIGLPGAAAYCASKGAVLALTRQAGVQYAPLGIKINS 179
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
V+PG +T +Q+ +++ Q AAFL T +GR + DEVA I FL SD AS + G
Sbjct: 180 VSPGTTMTGIQK--NVTDAQRAAFLPLT----PIGRFAEADEVARVILFLCSDGASFMAG 233
Query: 240 ASVPVDGGRHAM 251
A V VDGG AM
Sbjct: 234 ADVSVDGGMVAM 245
>UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
dehydrogenase/reductase SDR - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 252
Score = 108 bits (260), Expect = 1e-22
Identities = 64/188 (34%), Positives = 97/188 (51%), Gaps = 3/188 (1%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D++ E +I ++ + YG+LDV+ NAG++ T +E+ S +++ + N+ + + LT
Sbjct: 63 DVSGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLT 122
Query: 121 MLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
A P + +G G +R G +AYN SK + TR +A ELAP +RVNC
Sbjct: 123 KYAAPVMRRHEGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLADELAPHNIRVNC 182
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
V PG + T R E A E L R P+EVA + FLA + AS ITG
Sbjct: 183 VCPGWVDTPFNR--PFWEHAGAGAEEEVLRGVPLRRQCTPEEVAPAVVFLAGEGASYITG 240
Query: 240 ASVPVDGG 247
++ +DGG
Sbjct: 241 EALVIDGG 248
>UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholderia
xenovorans LB400|Rep: Putative dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 291
Score = 108 bits (260), Expect = 1e-22
Identities = 70/197 (35%), Positives = 102/197 (51%), Gaps = 11/197 (5%)
Query: 55 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNV 113
++SI D+ ES ++ +T++H+G+ DVL+NNA + T IE +A +DR + N+
Sbjct: 69 SVSIECDVADESSVKNAAGRTVEHFGRCDVLINNAATLAPATSIEKLLVADWDRTLAINL 128
Query: 114 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLA-YNISKASVDQFTRCVALELAP 172
R ++ LT + L+ ++G + P Y SKA+V FTR A+E P
Sbjct: 129 RGVF-LTTKYLGALMLNQGSGSIVNIASIAATAPNASPQYGASKAAVLAFTRHTAVEWGP 187
Query: 173 KGVRVNCVNPGVILTELQRRGGLSEEQYA--AFLERTKETHALGRPGKPDEVAATIAFLA 230
+G+R N V+PG I T LSE YA L R R G P ++A +AFLA
Sbjct: 188 RGIRANAVSPGFIRTP------LSESNYAEPEMLARRSNMVPSRRLGLPGDIAEAVAFLA 241
Query: 231 SDLASNITGASVPVDGG 247
D AS I G + VDGG
Sbjct: 242 GDGASFINGQELAVDGG 258
>UniRef50_Q0FPS1 Cluster: Probable dehydrogenase; n=1; Roseovarius
sp. HTCC2601|Rep: Probable dehydrogenase - Roseovarius
sp. HTCC2601
Length = 251
Score = 108 bits (260), Expect = 1e-22
Identities = 62/194 (31%), Positives = 99/194 (51%), Gaps = 6/194 (3%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGK-LDVLVNNAGIIETGTIENTSLAQ-YDRLMNTNV 113
+++ D+ + + E + ++T +G D+LVNNAGII + S +D +M N
Sbjct: 58 IALGLDVARRASCEALAQETESRFGAPTDILVNNAGIIRRTPPDAESFEDDWDAMMRVNA 117
Query: 114 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 173
+ +P L +KG + PG++AY SK +V Q TR + +L+
Sbjct: 118 TGCMNMVRAFLPQLKRTKGRIVNLGSIMSVSGGPGLVAYAASKGAVLQMTRALTHDLSEH 177
Query: 174 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 233
G+RVN + PGVI T + + E F+ T + RPG+P E+ + FLAS+
Sbjct: 178 GIRVNAIAPGVIETPMTAATRENPEAIGRFMAHT----PMRRPGQPSELVGPVLFLASEA 233
Query: 234 ASNITGASVPVDGG 247
+S +TGA +PVDGG
Sbjct: 234 SSYVTGALLPVDGG 247
>UniRef50_Q04DL8 Cluster: Acetoin reductase; n=2; Oenococcus
oeni|Rep: Acetoin reductase - Oenococcus oeni (strain
BAA-331 / PSU-1)
Length = 257
Score = 108 bits (260), Expect = 1e-22
Identities = 71/231 (30%), Positives = 116/231 (50%), Gaps = 8/231 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
LSK G + + GR E L KV+++ + ++ D++ +S E+++KK +G+LD
Sbjct: 23 LSKDGYSVIINGRTQEKLDKVAEEIKNNNGKVITFVGDVSSKSANEQLVKKAESEFGRLD 82
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 141
V V NAGI TIE T Q D ++N N++S + A + +S G
Sbjct: 83 VFVANAGIDWVDTIEGTPADQVDNVININLKSQIWALQTAPKVMRKSGDGGSIVLASSIA 142
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL-QRRGGLSEEQY 200
G+ F + Y+ +K + + A ELA +RVN NPG++LT + E+
Sbjct: 143 GMEGFEMLGIYSATKFATRGLVQAAAKELAVDKIRVNAYNPGIVLTPMWDEIDARFAERK 202
Query: 201 AAFLERTKETH----ALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ T++ LGR +P++VA ++FL+ D + ITG S+ VDGG
Sbjct: 203 NVPVGSTRQAFIDGILLGRGEEPEDVAKLVSFLSGDESDYITGQSIAVDGG 253
>UniRef50_Q7UP98 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=4; Bacteria|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family - Rhodopirellula baltica
Length = 273
Score = 108 bits (259), Expect = 2e-22
Identities = 76/229 (33%), Positives = 114/229 (49%), Gaps = 13/229 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-----TLSITADLTKESDIEKIIKKTIDHY 79
L+ GA + L RN Q+ S +K A ++ I AD+T E+D+ +++ +D
Sbjct: 48 LASAGANVCLVSRNE---QEASAAAEKIAGEYPVRSIGIGADVTVEADVANMVQACVDQL 104
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXX 138
LDVL+N+AGI G+I+ SL Q+ ++ +TNV ++ A + ++ G
Sbjct: 105 SGLDVLINSAGINVRGSIDELSLEQFRQVQSTNVDGMWLCCKHASSVMKKNGSGRIINLA 164
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 198
G+ Y SK +V Q TR + LELAP V VN + PG LT + SEE
Sbjct: 165 STLGLVGLANRTPYASSKGAVVQMTRALGLELAPHNVTVNAICPGPFLTPMNVPIADSEE 224
Query: 199 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ T AL R G+ E+ FLASD +S +TG+ + VDGG
Sbjct: 225 AKRFIVGAT----ALERWGQMQEIQGAAIFLASDASSYMTGSMLTVDGG 269
>UniRef50_Q4FPW9 Cluster: Possible Short-chain
dehydrogenase/reductase; n=2; Psychrobacter|Rep:
Possible Short-chain dehydrogenase/reductase -
Psychrobacter arcticum
Length = 265
Score = 108 bits (259), Expect = 2e-22
Identities = 70/230 (30%), Positives = 112/230 (48%), Gaps = 11/230 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDK------FASTLSITADLTKESDIEKIIKKTIDHYGKL 82
GA + L GR+ + L ++++ + + L+I D+ ES ++++IK+ ID + K+
Sbjct: 30 GANVILVGRSADILNQITERFPQDHTWIHTENFLTIACDIGVESQVQEMIKRVIDKFEKI 89
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
D+LVNNA G S Q ++ + Y+ A+PHL++SKG
Sbjct: 90 DILVNNAAQTTQGDNGGVSTEQEHLAIDDYLSETLYVCQTAMPHLIQSKGNIINVPSFAA 149
Query: 143 IRS----FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR-GGLSE 197
S Y+ + + + TR +A E + GVRVN V P V +++
Sbjct: 150 CSSDQSAATSAATYDAALSGITDLTRTLASEHSADGVRVNAVTPSVTQSDVSDAIQNTDI 209
Query: 198 EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
A ++ + LGR P ++AA I FLASD AS ITG ++PVDGG
Sbjct: 210 TDIQANIDELPDNSPLGRCATPSDIAAVITFLASDDASMITGTNLPVDGG 259
>UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Carboxydothermus
hydrogenoformans Z-2901|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Carboxydothermus
hydrogenoformans (strain Z-2901 / DSM 6008)
Length = 249
Score = 108 bits (259), Expect = 2e-22
Identities = 69/225 (30%), Positives = 116/225 (51%), Gaps = 6/225 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
+++ GA++ + RN E +K + +K SI D+ K +DI+K++ + YG++D
Sbjct: 26 IAEEGAKVVIANRNKEEGEKAALQLREKGLEVYSIPCDVGKVADIKKLVSEVYGRYGRID 85
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 142
+LVN AG+ IE + ++ +++ N++ ++ + A H++ K G
Sbjct: 86 ILVNCAGVNVRKPIEEYTEEDWNYMVDINLKGTFFACIEAGKHMIAQKEGVIVNLASIQA 145
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
P Y +K V Q T+ +A+E A +RVN V+P I TE+ + + ++ Y
Sbjct: 146 EEVLPERGIYATTKGGVKQLTKALAVEWAKYNIRVNAVSPAFIKTEMVEK--VLQDPYWG 203
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
L K + RPG P+EVA I FL S AS ITG ++ VDGG
Sbjct: 204 NLIINKT--PMRRPGTPEEVAEAILFLVSPKASYITGINLLVDGG 246
>UniRef50_Q12JI9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Shewanella|Rep: Short-chain dehydrogenase/reductase
SDR - Shewanella denitrificans (strain OS217 / ATCC
BAA-1090 / DSM 15013)
Length = 257
Score = 108 bits (259), Expect = 2e-22
Identities = 73/248 (29%), Positives = 113/248 (45%), Gaps = 5/248 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 60
M+ GK V LS+LGA++ LTGRN L++ +++
Sbjct: 10 MDLTGKQVLVTGASAGIGRACCTLLSQLGAKIILTGRNQAGLEETLSSLSGNGHKIAVF- 68
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+ + + +K YG LD V+ AG+ T I + +D M+ N+ S +T
Sbjct: 69 DIKNINGLGDWVKYLRSEYGYLDSFVHCAGVQITKPIRSFDQGFFDDTMHVNLASAMAIT 128
Query: 121 M-LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 179
+ +G G+ G Y SKA + TR +A+EL +RVNC
Sbjct: 129 QGFRLKRDRSKQGSIVFVSSIAGLIGQTGNTVYGASKAGLMSLTRGLAMELLRDNIRVNC 188
Query: 180 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 239
V P ++ TE+ +R + AA + + H +G GKPD+VA +AFL SD A I
Sbjct: 189 VAPALVETEMAQRA--QDSMTAAQFQHMLDQHPMGL-GKPDDVANAVAFLLSDAAKWINA 245
Query: 240 ASVPVDGG 247
++PV+GG
Sbjct: 246 VTLPVEGG 253
>UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=9; Bacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
sp. (strain RHA1)
Length = 249
Score = 108 bits (259), Expect = 2e-22
Identities = 69/212 (32%), Positives = 109/212 (51%), Gaps = 10/212 (4%)
Query: 29 GAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA L L R+ E L VS+ + A + + D+T + ++ + + +G LD+LVN
Sbjct: 30 GAHLLLADRDEERLAAAVSRYSEGEAKAVGVVVDVTDPDQTKMMVDRCLAEFGALDILVN 89
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSF 146
AG++ + +A +D +++ ++RS++ AVPH+L + G GI+
Sbjct: 90 CAGLLTEVPLAEMDVATWDEMISVDLRSVFLCCRWAVPHMLAQGSGRIINISSQLGIKGG 149
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 206
G++ Y +KA V TR +A ELAP GV VN + PG + T L G++E+ +
Sbjct: 150 VGLVHYCAAKAGVIGLTRALARELAPSGVLVNAIAPGPVWTPL--FAGITED-----WRQ 202
Query: 207 TKETH-ALGRPGKPDEVAATIAFLASDLASNI 237
KE LGR G P E+A T LASD N+
Sbjct: 203 AKEAELPLGRFGLPHEIAPTAVLLASDPGGNL 234
>UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Caulobacter sp. K31|Rep: Short-chain
dehydrogenase/reductase SDR - Caulobacter sp. K31
Length = 254
Score = 108 bits (259), Expect = 2e-22
Identities = 74/222 (33%), Positives = 107/222 (48%), Gaps = 7/222 (3%)
Query: 29 GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 87
GA + +T E + V+ D + L I D+ + ++ K +D +GK+DVLVN
Sbjct: 33 GAAVIITDVQREEGEAVAADILAQGGKALFIAHDVGDAEAWDVVVAKALDTFGKVDVLVN 92
Query: 88 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG--IRS 145
NAG+I+ +E + +DR+ NVR + +P L + G I
Sbjct: 93 NAGLIQFAPLEEMPIEMFDRVTRVNVRGPWLGCKAILPALKAAGGGAIINMSSMNGMIAQ 152
Query: 146 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 205
PG+ AY SK +V T+ VA + GVRVN V+PG I + +
Sbjct: 153 NPGLSAYATSKGAVRMLTKAVAQDYVQYGVRVNSVHPGTIASTFVAPFLEDPNWRDKLVG 212
Query: 206 RTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
RT + R G+P EVA +AFLASD AS +TG+ V VDGG
Sbjct: 213 RT----PMARAGEPSEVAKVVAFLASDDASYMTGSEVAVDGG 250
>UniRef50_Q0I8V1 Cluster: Glucose 1-dehydrogenase; n=5;
Bacteria|Rep: Glucose 1-dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 265
Score = 108 bits (259), Expect = 2e-22
Identities = 67/228 (29%), Positives = 117/228 (51%), Gaps = 10/228 (4%)
Query: 25 LSKLGAQLSLTGRN-VENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKL 82
+ LGA++ + R+ E +++ ++ + ++ + AD++K D++ +I + +GK+
Sbjct: 35 VGSLGAKVVIDYRSHPERTEELIEEVGELGGQSIGVQADVSKLVDLQHLIDTAVQTFGKI 94
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
DV+VNNAGI +I +TS +D++MN N+R +++ T A ++ S+G
Sbjct: 95 DVMVNNAGIETRTSILDTSPDDFDKVMNVNLRGVFFATQYAAKQMI-SQGSGGRIINISS 153
Query: 143 IRS---FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 199
+ P Y ++K V TR +ELA KGV + V PG + T + S
Sbjct: 154 VHEDWPMPNNTPYCVAKGGVRMLTRTAGVELAGKGVSIVNVGPGAVATPIND----STMN 209
Query: 200 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
L + +GR +P E+A+ +AFLA + AS +T SV DGG
Sbjct: 210 DPELLAKLNAAIPIGRMAQPAEIASVVAFLAGNGASYMTATSVFADGG 257
>UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - unidentified eubacterium SCB49
Length = 256
Score = 108 bits (259), Expect = 2e-22
Identities = 62/197 (31%), Positives = 107/197 (54%), Gaps = 7/197 (3%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQYDRLMNTNVRSI 116
I+ DLTKE+D ++K+T++ G LD+L+NNAG ++ + + ++M+ N+ S+
Sbjct: 64 ISGDLTKEADANTLVKQTVEALGGLDILINNAGSLVARKLLSEMETEFWHKVMDINLTSM 123
Query: 117 YYLTMLAVPHLLESKGXXXXXXXXXGIRS--FPGVLAYNISKASVDQFTRCVALELAPKG 174
++T A P+L +++ R PG L Y+ SK ++ FTR ++ EL +G
Sbjct: 124 MFVTRAASPYLAKNENSSIVNLASLAGRKGGHPGSLVYSTSKGAILTFTRALSTELGAQG 183
Query: 175 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 234
+RVN V+PG+IL ++E A T + R G +VA + +LAS+
Sbjct: 184 IRVNAVSPGLILGTSFHNTHTTKESAA----ETTAGIPIQRAGNAADVARAVLYLASEYD 239
Query: 235 SNITGASVPVDGGRHAM 251
ITGA++ ++GG + M
Sbjct: 240 GFITGATLDINGGVYNM 256
>UniRef50_A5VEH5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Sphingomonas wittichii RW1|Rep: Short-chain
dehydrogenase/reductase SDR - Sphingomonas wittichii RW1
Length = 268
Score = 108 bits (259), Expect = 2e-22
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 9/221 (4%)
Query: 31 QLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAG 90
++++ GR L V+ + + +D+ K++ + H+G+LD LV NAG
Sbjct: 34 RVAICGRRKAPLDAVAAE----TGAVPFVSDVGDPEAARKLVADVVAHFGRLDGLVLNAG 89
Query: 91 IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVL 150
I+ SL +++ + N+ + LT A+PHLL KG G+++ PG+
Sbjct: 90 ILINAPFGEMSLDAWNQQIGINLTGPFVLTQAALPHLLARKGAVVSITSVGGVQTGPGLA 149
Query: 151 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE----R 206
AY+ SKA + T+ +A E A G+R N V PG I TE+ + Q A LE +
Sbjct: 150 AYSASKAGLQLMTQALAYEHARDGLRANIVAPGWIRTEMGDE-EMETMQIADDLEGAYAK 208
Query: 207 TKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E R G DE A IA+L S AS + GA + VDGG
Sbjct: 209 VSEFVPQRRAGSSDEAAEAIAWLLSPAASFVNGAVLAVDGG 249
>UniRef50_A1ZIV8 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Sphingobacteriales|Rep: Short-chain
dehydrogenase/reductase SDR - Microscilla marina ATCC
23134
Length = 273
Score = 108 bits (259), Expect = 2e-22
Identities = 59/158 (37%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Query: 27 KLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 85
K GA++ +TGRN E L KVS + + L I AD + ESD + ++K+TID YGK+DVL
Sbjct: 30 KAGAKVVITGRNNEKLVKVSDMLNIEQIDNLPIVADSSVESDCKMVVKETIDKYGKIDVL 89
Query: 86 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS 145
+NNAGI L+ +R+M N Y+T A+P+L +++G G R
Sbjct: 90 INNAGISMRAMFAELDLSVIERVMQINFFGTVYITKFALPYLTQTQGSIVGVSSIAGFRG 149
Query: 146 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 183
PG Y+ SK ++ F + EL K V V PG
Sbjct: 150 LPGRTGYSASKFAMQGFLESLRTELLKKNVNVLVAAPG 187
>UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
Short-chain dehydrogenase/reductase SDR - Halorubrum
lacusprofundi ATCC 49239
Length = 263
Score = 108 bits (259), Expect = 2e-22
Identities = 70/227 (30%), Positives = 112/227 (49%), Gaps = 9/227 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLD 83
++ GA + + R ++ V+ + F ITAD+T + D+E ++++ +D +G LD
Sbjct: 38 MAAAGATVVPSARTAAEVEAVADEARDFGVEARGITADVTDDDDVEALVEEIVDAFGSLD 97
Query: 84 VLVNNAGIIETGTIENTSLAQ---YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX 140
+LVNNAG + + + + D +++ N+R + A PHL E+ G
Sbjct: 98 ILVNNAGFNPGDALGDPAEIESDAVDSVLDVNLRGAFRTLRAAGPHLKEAGGSVVNVASV 157
Query: 141 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 200
G P Y SK + T+ A++ AP+ VRVN V PG + T+L +E
Sbjct: 158 AGEVGLPKQHPYVASKHGLVGLTKSAAMDWAPE-VRVNAVAPGYVATDLTETLQENERLR 216
Query: 201 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+ L+RT L R P E+A FLASD AS +TG ++ DGG
Sbjct: 217 QSILDRT----PLDRFADPMEIAGPAVFLASDAASFVTGETLAADGG 259
>UniRef50_Q9BY49 Cluster: Peroxisomal trans-2-enoyl-CoA reductase;
n=32; Eumetazoa|Rep: Peroxisomal trans-2-enoyl-CoA
reductase - Homo sapiens (Human)
Length = 303
Score = 108 bits (259), Expect = 2e-22
Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 8/230 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 78
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 79 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 138
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 157
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 198
FP + ++A V T+ +ALE A G+R+NCV PGVI ++ S
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWG 217
Query: 199 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
Q +F E + + R G P+EV++ + FL S AS ITG SV VDGGR
Sbjct: 218 Q--SFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGR 265
>UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=3; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
protein) reductase - Bacillus halodurans
Length = 246
Score = 107 bits (258), Expect = 2e-22
Identities = 70/226 (30%), Positives = 116/226 (51%), Gaps = 9/226 (3%)
Query: 25 LSKLGAQLSLT-GRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKL 82
L++ GA + + N E +KV + + ++I AD+ ++ ++K+TID +G +
Sbjct: 24 LARHGANVVVNYAGNKEKAEKVVAEIKELGVEAIAIQADVADSESVQAMVKETIDTFGAV 83
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXX 141
D+LVNNAGI +D +++TN++ +++ + P + + G
Sbjct: 84 DILVNNAGITRDNLFMRMKEEDWDAVIDTNLKGVFHCSKAVTRPMMKQRFGRIINVSSVV 143
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G G Y +KA V T+ +A ELA + + VN V PG I T++ G L E+ A
Sbjct: 144 GAIGNAGQANYVAAKAGVIGLTKTLARELANRNITVNAVAPGFIETDM--TGELPEDVKA 201
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
L + L R G+P+EVA + FLASD AS +TG ++ V+GG
Sbjct: 202 QMLGQI----PLARLGQPEEVAKAVRFLASDDASYLTGQTIHVNGG 243
>UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN)
REDUCTASE; n=6; Brucellaceae|Rep:
3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE - Brucella
melitensis
Length = 249
Score = 107 bits (258), Expect = 2e-22
Identities = 68/221 (30%), Positives = 119/221 (53%), Gaps = 6/221 (2%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
GA++ L NV+ ++ D ++ +SI AD+++++D+E++ + + +G++D++VNN
Sbjct: 30 GARVVLADVNVKRVEDGLADIS--SNGISIQADVSRKNDMERVARTAFEEFGRIDIMVNN 87
Query: 89 AGIIETG-TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGIRSF 146
AG + + +D ++ N++++YY T L VP + + G G+
Sbjct: 88 AGFTHRNMPLTDVDEHNFDLIVAVNMKALYYSTQLVVPIMEHQGGGVIINTASATGLHPR 147
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 206
G+ Y SK+ V T+ +ALELA + +RVNC+ P E + L+E+ A
Sbjct: 148 KGLTWYCASKSWVVSATKAMALELAERNIRVNCLCPAESDGE-GLKMFLAEDTPEA-RAA 205
Query: 207 TKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
K T LGR P +VA +LASD AS +TG ++ +DGG
Sbjct: 206 LKSTIPLGRFSTPKDVAEAALWLASDDASMVTGVALGIDGG 246
>UniRef50_Q3M510 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Nostocaceae|Rep: Short-chain
dehydrogenase/reductase SDR - Anabaena variabilis
(strain ATCC 29413 / PCC 7937)
Length = 294
Score = 107 bits (258), Expect = 2e-22
Identities = 72/260 (27%), Positives = 120/260 (46%), Gaps = 16/260 (6%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF----ASTL 56
+N GK L G +++ R+ E L+ A +
Sbjct: 33 LNLTGKTAIVTGGSAGIGLAVAKALYSEGVNVAIASRSQERLENAVSAIQSLPTPGAKVI 92
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 116
+I+ADLT+ +++++ T+ +G++D+L+NNAG G+ +++ + N +
Sbjct: 93 AISADLTQAESVDRVVSSTLAQFGQIDILINNAGSARAGSFLDSTDDLFLDAWNLKLLGY 152
Query: 117 YYLTMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 175
VPHL + G G P LA S A++ FT+ ++ ELA +
Sbjct: 153 IRFVRAVVPHLRSQGDGRIVNIIGGAGRTPRPNFLAGGTSNAALLNFTKGISKELAEYNI 212
Query: 176 RVNCVNPGVILTE----LQRRG----GLSEEQYAAFLERTKETHALGRPGKPDEVAATIA 227
R+N ++PG TE L R+ G++ EQ A + ++ L R +PDE+AA
Sbjct: 213 RINAISPGATATERAETLARQNAQARGITVEQAKA---ESLQSIPLKRIAQPDEIAALAL 269
Query: 228 FLASDLASNITGASVPVDGG 247
FL SDLA++ITG + VDGG
Sbjct: 270 FLVSDLAASITGTEIIVDGG 289
>UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Chloroflexus aurantiacus
J-10-fl
Length = 249
Score = 107 bits (258), Expect = 2e-22
Identities = 75/251 (29%), Positives = 116/251 (46%), Gaps = 10/251 (3%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSIT 59
M F GKV L GA + L R +E L+ V + D K A TL++
Sbjct: 1 MEFEGKVALVTGAGTGIGEAIAERLLAGGALVVLVSRRLEPLELVCRRIDPKGARTLALE 60
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYDRLMNTNVRSIY 117
AD+ +E +K+TI+ +GKLD+ VNNAG+ +++ + +++T++ I+
Sbjct: 61 ADVRNPMAMEAAVKRTIERFGKLDMAVNNAGVTGPAGVPVQDVEAEIWREVIDTDLTGIF 120
Query: 118 YLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
Y +P +L G G+ G+ AY +K V TR ALELA +R
Sbjct: 121 YSMKYEIPAMLANGSGAIVNMSSANGLVGLAGMAAYTAAKHGVIGLTRSAALELAESNIR 180
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
V V PG + T G + A L H + R +EVA +A+L S+ A+
Sbjct: 181 VCAVAPGYVATPRIMDSGKEVTDWMASL------HPMKRLATREEVADFVAYLLSERAAF 234
Query: 237 ITGASVPVDGG 247
+TG+ +DGG
Sbjct: 235 MTGSVHSIDGG 245
>UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Kineococcus radiotolerans SRS30216|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Kineococcus radiotolerans SRS30216
Length = 247
Score = 107 bits (258), Expect = 2e-22
Identities = 78/226 (34%), Positives = 108/226 (47%), Gaps = 12/226 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLD 83
L+ GA + ++GR+ + + T + ADL+ S + ++ +D G +D
Sbjct: 27 LAARGAHVLVSGRDDTRGRDAVQSLVNAGGTAEYLPADLSAASGVRELADAALDLAGTVD 86
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 143
+LVNNAG+ G+ S DR+ NV++ Y L P ++E +G G
Sbjct: 87 ILVNNAGVFSFGSTAGNSEIDIDRMYAINVKAPYLLVQALAPKMVE-QGSGTIVNVLTGA 145
Query: 144 RSFPGVLA--YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
V A Y SKA++ T A E P GVRVN V+PG I TE G
Sbjct: 146 AHRGSVTAGLYGSSKAALLLLTTAWAAEFGPSGVRVNAVSPGPIRTEGTANG-------- 197
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
A L+ R G+P EVAA +AFLASD AS I GA +PVDGG
Sbjct: 198 AGLDAVARALPARRLGEPVEVAAAVAFLASDDASYIHGAILPVDGG 243
>UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Marinomonas sp. MWYL1
Length = 258
Score = 107 bits (258), Expect = 2e-22
Identities = 71/247 (28%), Positives = 122/247 (49%), Gaps = 9/247 (3%)
Query: 6 KVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITA-DLT 63
KVV + GA L L N +L+ + + ++++ T+S A D+T
Sbjct: 12 KVVVITGAASGIGLESAKAFAACGASLVLIDFNQSSLESLKETLLNQYSITISTYAVDVT 71
Query: 64 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM-L 122
E+ I + + +G++DVLVN+AGI + + S ++++++ N+ ++
Sbjct: 72 NEAAIVDCAQNAMSTFGQIDVLVNSAGIALLHSAADISSEDWNKVLDVNINGTFWACRAF 131
Query: 123 AVPHLLESKGXXXXXXXXXG--IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
A + + G G I +Y +SKA+V Q T+ +A+E A +G+RVN +
Sbjct: 132 AAQMMKQGSGSIINLGSMSGSVINQPQFASSYMVSKAAVHQLTKALAVEWAQQGIRVNAL 191
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PG + T++ E + +LE T LGR G P E+AA I FL SD ++ +TG+
Sbjct: 192 APGYVATDMTLEMRAQPELFYKWLEMT----PLGRLGSPSEIAAMILFLGSDASTYLTGS 247
Query: 241 SVPVDGG 247
V +DGG
Sbjct: 248 VVAIDGG 254
>UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=2;
Bacteria|Rep: Predicted short chain dehydrogenase -
Bacillus sp. B14905
Length = 251
Score = 107 bits (258), Expect = 2e-22
Identities = 71/225 (31%), Positives = 110/225 (48%), Gaps = 6/225 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLD 83
++K GA +++ N E + + KD + + ++ + A+L + + KII ++ YGKLD
Sbjct: 26 MAKEGAIVTIVDLNAEAGEAMEKDLQQISPKSMFLQANLMERDQLPKIIDTVVEKYGKLD 85
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 143
VLVNNA + TIE T+ A D T +YL A+PHL E++G GI
Sbjct: 86 VLVNNAHAAKQVTIEETTQADLDLSFGTGFYPTFYLMQAALPHLKETQGNIINFASGAGI 145
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 203
+ AY +K ++ +R A E G+ VN ++P +Q E Y
Sbjct: 146 QGHETQAAYAAAKEAIRGISRVAANEWGRYGINVNIISPLADSPGVQAWAKAQPEYY--- 202
Query: 204 LERTKETHALGRPGKPDEVAATIA-FLASDLASNITGASVPVDGG 247
E + LGR G ++ +A FLASD + ITG ++ VDGG
Sbjct: 203 -EAVRNKIPLGRFGHIEQDIGRVAVFLASDDSQYITGQTIMVDGG 246
>UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=1; Mycobacterium smegmatis str. MC2
155|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 236
Score = 107 bits (258), Expect = 2e-22
Identities = 63/192 (32%), Positives = 98/192 (51%), Gaps = 6/192 (3%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L++ AD+T E D+ K+ + YG++D LV AG++E + + LA +++ + N+
Sbjct: 47 LTVPADVTSEHDVAKLTSAAVIEYGRIDALVTLAGVMEQTLLPDLDLATWNQTIAVNLTG 106
Query: 116 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 175
+ A L+++ G G AY SKA V TR +A EL P V
Sbjct: 107 TFLCAKAAADELMKTGGTIVTIGSQIGYVGGINCAAYTASKAGVAGLTRALARELGPT-V 165
Query: 176 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
RVNCV PG I T + E ++E+ + +GR G PDEVA +++L D AS
Sbjct: 166 RVNCVAPGPIETPMTAVHATPE-----WVEQKTRSLVMGRFGTPDEVATAVSWLVGDEAS 220
Query: 236 NITGASVPVDGG 247
+TG ++ V+GG
Sbjct: 221 FVTGQTINVNGG 232
>UniRef50_Q2UFW9 Cluster: Dehydrogenases with different
specificities; n=7; cellular organisms|Rep:
Dehydrogenases with different specificities -
Aspergillus oryzae
Length = 298
Score = 107 bits (258), Expect = 2e-22
Identities = 65/208 (31%), Positives = 105/208 (50%), Gaps = 13/208 (6%)
Query: 52 FASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMN 110
+ + ++ AD+T D E I+ + + +LD+LVNN GI GT + + ++ + +
Sbjct: 81 YGNATAMQADVTNPGDCESIVSTALTTFNRLDILVNNVGISGAAGTAVDVDMEEWAKSLE 140
Query: 111 TNVRSIYYLTMLAVPHLLES--------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQF 162
NV S+ +++ A+P ++++ +G G+R L Y SK +V Q
Sbjct: 141 VNVSSMVFVSKYAIPAMMQNERDEYSGMRGSIVNMGSVAGLRGGTPHLLYPTSKGAVVQL 200
Query: 163 TRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEV 222
TR +A AP G+RVNCV PG++ T + GG+SEE A +R+ L G +
Sbjct: 201 TRAMAAHHAPDGIRVNCVCPGMLFTPMMYGGGMSEEAREARRKRS----LLQTEGNGWDC 256
Query: 223 AATIAFLASDLASNITGASVPVDGGRHA 250
A + FLA A +TG +PVD G A
Sbjct: 257 ATAVVFLAGPHARWMTGVILPVDAGTTA 284
>UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=11; Bacteria|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Xylella fastidiosa
Length = 255
Score = 107 bits (257), Expect = 3e-22
Identities = 67/250 (26%), Positives = 120/250 (48%), Gaps = 8/250 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITA 60
+F G+V ++ GA + L R+ E Q+ + + + + +
Sbjct: 6 DFKGQVALVTGAAAGMGLATARGFAQGGASVVLADRDGERAAQEAAAIVAEGGTAIGLAC 65
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 119
D++ E+ + +++KT+ YG+LD NNAG++ + + ++DR++ N+R ++
Sbjct: 66 DVSDEAQVAALVEKTVAEYGRLDFAFNNAGVMAKIAPFAEATSEEFDRVIGINLRGVWLC 125
Query: 120 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 178
+ + + G + G+ AY SK V TR ALE KG+RVN
Sbjct: 126 MKYELQQMQRQGSGVIVNNASVGALTGNVGIGAYIASKHGVLGLTRAAALEYCKKGIRVN 185
Query: 179 CVNPGVILTELQRR-GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 237
VNPG I T++ R G S+E +A + + +GR G+P+E+A+ + +L S S +
Sbjct: 186 AVNPGTIDTQIARDVVGGSDEAFA----KLGASAPIGRAGRPEEIASAVLWLCSPGGSYV 241
Query: 238 TGASVPVDGG 247
G + VDGG
Sbjct: 242 IGEGLTVDGG 251
>UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=14; Clostridia|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Clostridium
tetani
Length = 249
Score = 107 bits (257), Expect = 3e-22
Identities = 58/191 (30%), Positives = 100/191 (52%), Gaps = 7/191 (3%)
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
I D++ D + +I+K I +GK+D+L+NNAGI + G + +D ++NTN++ ++
Sbjct: 63 IKCDVSSYEDTKLMIEKIIRDFGKIDILINNAGISKIGLFIDMEEEDWDNIINTNLKGVF 122
Query: 118 YLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 176
+ +P+++ E G G + Y+ SK VD FT+ +A E+ P +R
Sbjct: 123 NCSRNVLPYMIGEKNGVIINISSMWGSVGASCEVIYSASKGGVDSFTKALAKEVGPSNIR 182
Query: 177 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
VN ++PGVI T + E+ + K+ L R G+ +++ + FL SD A
Sbjct: 183 VNAISPGVINTSMNEWMSCEEK------DSLKDEIPLCRFGECEDIGKAVVFLCSDNAKY 236
Query: 237 ITGASVPVDGG 247
ITG + +DGG
Sbjct: 237 ITGQILTIDGG 247
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.317 0.134 0.375
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 230,088,319
Number of Sequences: 1657284
Number of extensions: 8458967
Number of successful extensions: 35074
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 3533
Number of HSP's successfully gapped in prelim test: 1126
Number of HSP's that attempted gapping in prelim test: 25983
Number of HSP's gapped (non-prelim): 5046
length of query: 254
length of database: 575,637,011
effective HSP length: 99
effective length of query: 155
effective length of database: 411,565,895
effective search space: 63792713725
effective search space used: 63792713725
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 71 (32.7 bits)
- SilkBase 1999-2023 -