Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001323-TA|BGIBMGA001323-PA|IPR002347|Glucose/ribitol
dehydrogenase, IPR002198|Short-chain dehydrogenase/reductase SDR
(254 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 110 5e-24
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 110 5e-24
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 110 5e-24
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 110 5e-24
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 109 7e-24
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 109 7e-24
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 109 7e-24
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 109 7e-24
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 109 7e-24
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 109 7e-24
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 109 7e-24
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 109 7e-24
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 109 1e-23
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 109 1e-23
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 108 2e-23
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 108 2e-23
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 108 2e-23
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 108 2e-23
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 107 3e-23
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 107 4e-23
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 99 2e-20
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 99 2e-20
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 99 2e-20
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 97 4e-20
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 91 5e-18
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 87 6e-17
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 87 7e-17
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 87 7e-17
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 80 6e-15
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 80 6e-15
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 80 6e-15
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 80 6e-15
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 80 6e-15
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 79 1e-14
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 78 3e-14
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 78 3e-14
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 78 3e-14
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 78 3e-14
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 78 3e-14
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 78 3e-14
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 78 3e-14
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 78 3e-14
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 72 2e-12
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 71 4e-12
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 71 4e-12
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 71 4e-12
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 71 4e-12
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 71 5e-12
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 71 5e-12
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 71 5e-12
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 71 5e-12
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 71 5e-12
AL645940-11|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 71 5e-12
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 71 5e-12
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 70 7e-12
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 68 4e-11
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 68 4e-11
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 67 6e-11
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 67 6e-11
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 67 6e-11
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 67 6e-11
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 67 6e-11
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 64 3e-10
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 64 5e-10
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 64 6e-10
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 64 6e-10
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 64 6e-10
AL023881-2|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 64 6e-10
AL023881-1|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 64 6e-10
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 64 6e-10
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 64 6e-10
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 63 1e-09
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 63 1e-09
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 63 1e-09
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 63 1e-09
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 62 2e-09
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 62 2e-09
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 62 2e-09
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 62 2e-09
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 62 2e-09
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 62 2e-09
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 62 2e-09
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 62 2e-09
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 62 2e-09
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 62 2e-09
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 62 2e-09
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 62 2e-09
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 62 2e-09
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 62 2e-09
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 62 2e-09
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 62 2e-09
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 61 3e-09
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 61 3e-09
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 61 3e-09
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 61 3e-09
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 61 4e-09
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 60 7e-09
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 60 7e-09
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 60 7e-09
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 60 7e-09
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 60 7e-09
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 60 7e-09
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 60 1e-08
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 60 1e-08
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 60 1e-08
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 60 1e-08
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 60 1e-08
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 59 1e-08
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 59 1e-08
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 56 9e-08
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 56 9e-08
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 56 9e-08
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 56 9e-08
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 56 9e-08
U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid deh... 56 2e-07
CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein. 56 2e-07
BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta... 56 2e-07
AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta... 56 2e-07
AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta... 56 2e-07
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 55 3e-07
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 55 3e-07
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 53 8e-07
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 53 8e-07
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 53 8e-07
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 53 8e-07
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 53 8e-07
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 53 8e-07
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 1e-06
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 1e-06
AL162732-2|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 1e-06
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxyacyl-Coenzyme A de... 52 2e-06
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 52 2e-06
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 52 2e-06
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 52 2e-06
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 52 2e-06
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 52 2e-06
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 52 2e-06
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 52 2e-06
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 52 3e-06
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 52 3e-06
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 52 3e-06
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 52 3e-06
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 51 5e-06
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 50 8e-06
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 50 8e-06
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 50 8e-06
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 50 8e-06
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 50 8e-06
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 50 8e-06
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 49 1e-05
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 49 2e-05
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 48 3e-05
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 48 3e-05
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 48 3e-05
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 48 3e-05
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 48 3e-05
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 48 3e-05
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 48 3e-05
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 47 6e-05
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 47 6e-05
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 47 7e-05
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 47 7e-05
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 47 7e-05
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 46 2e-04
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 46 2e-04
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 46 2e-04
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 45 2e-04
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 44 4e-04
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 44 4e-04
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 44 7e-04
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 44 7e-04
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 44 7e-04
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 44 7e-04
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 44 7e-04
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 44 7e-04
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 44 7e-04
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 44 7e-04
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 43 0.001
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 43 0.001
BC064525-1|AAH64525.1| 309|Homo sapiens retinal short chain deh... 42 0.003
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 42 0.003
BC037219-1|AAH37219.2| 309|Homo sapiens retinal short chain deh... 42 0.003
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 42 0.003
AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid ... 42 0.003
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 42 0.003
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 42 0.003
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 42 0.003
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 42 0.003
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 42 0.003
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 42 0.003
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 42 0.003
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 42 0.003
Z97054-9|CAI42652.1| 252|Homo sapiens hydroxyacyl-Coenzyme A de... 41 0.004
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 41 0.004
AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase... 41 0.004
DQ338571-1|ABC61321.1| 160|Homo sapiens NADP(H)-dependent retin... 40 0.006
AY943857-1|AAX49568.1| 57|Homo sapiens NADP(H)-dependent retin... 40 0.006
AY616183-1|AAT70758.1| 91|Homo sapiens NADP(H)-dependent retin... 40 0.006
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 40 0.006
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 40 0.006
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 40 0.011
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 40 0.011
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 40 0.011
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 40 0.011
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 40 0.011
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 40 0.011
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 40 0.011
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 40 0.011
AY268353-1|AAP42287.1| 199|Homo sapiens short-chain dehydrogena... 38 0.034
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 37 0.079
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 36 0.18
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 36 0.18
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 36 0.18
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 36 0.18
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 36 0.18
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 36 0.18
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 36 0.18
AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens ... 35 0.32
BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 1... 33 0.73
AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein. 33 0.73
AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein. 33 0.73
AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein. 33 0.73
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 33 0.97
AY123250-1|AAM64254.1| 986|Homo sapiens RTN4 isoform G protein. 32 1.7
AY123249-1|AAM64253.1| 986|Homo sapiens RTN4 isoform F protein. 32 1.7
AY123248-1|AAM64252.1| 986|Homo sapiens RTN4 isoform E protein. 32 1.7
AY123247-1|AAM64251.1| 986|Homo sapiens RTN4 isoform D protein. 32 1.7
AY123246-1|AAM64250.1| 986|Homo sapiens RTN4 isoform Ab protein. 32 1.7
AY123245-1|AAM64249.1| 986|Homo sapiens RTN4 isoform Aa protein. 32 1.7
AY102285-4|AAM64244.1| 986|Homo sapiens RNT4 protein. 32 1.7
AY102285-1|AAM64243.1| 1192|Homo sapiens RTN4 protein. 32 1.7
AY102279-1|AAM64248.1| 1192|Homo sapiens RTN4 isoform A protein. 32 1.7
AJ251383-1|CAB99248.1| 1192|Homo sapiens Nogo-A protein protein. 32 1.7
AF333336-1|AAK20831.1| 986|Homo sapiens testis specific reticul... 32 1.7
AF148537-1|AAG12176.1| 1192|Homo sapiens reticulon 4a protein. 32 1.7
AC092461-1|AAX93116.1| 818|Homo sapiens unknown protein. 32 1.7
AB073359-1|BAE45717.1| 294|Homo sapiens NOGO-A protein. 32 1.7
AB040462-1|BAB18927.1| 1192|Homo sapiens RTN-xL protein. 32 1.7
AB020693-1|BAA74909.2| 1233|Homo sapiens KIAA0886 protein protein. 32 1.7
BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein. 32 2.2
BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein. 32 2.2
AY313896-1|AAP83168.1| 234|Homo sapiens short-chain dehydrogena... 32 2.2
AY268351-1|AAP42285.1| 205|Homo sapiens short-chain dehydrogena... 32 2.2
Z97054-7|CAI42651.1| 169|Homo sapiens hydroxyacyl-Coenzyme A de... 31 3.0
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 31 3.0
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 31 3.0
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 31 3.9
AF240697-1|AAF82747.1| 172|Homo sapiens retinol dehydrogenase h... 31 5.2
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 30 9.1
AL136173-3|CAI23309.1| 148|Homo sapiens dynein, light chain, ro... 30 9.1
AL109923-4|CAI21457.1| 148|Homo sapiens dynein, light chain, ro... 30 9.1
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 30 9.1
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 30 9.1
AB209992-1|BAE06074.1| 2319|Homo sapiens DSP variant protein pro... 30 9.1
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 110 bits (264), Expect = 5e-24
Identities = 68/224 (30%), Positives = 118/224 (52%), Gaps = 6/224 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 84 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 175
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+ YN+SK ++ TR +ALELAPK +RVNCV PG+I T+ + +E +
Sbjct: 176 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 235
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDG 246
F KE H L R G+ ++ A ++FL S AS + G ++ V G
Sbjct: 236 F----KEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAG 275
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 110 bits (264), Expect = 5e-24
Identities = 68/224 (30%), Positives = 118/224 (52%), Gaps = 6/224 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 47 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 106
Query: 84 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 107 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 166
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+ YN+SK ++ TR +ALELAPK +RVNCV PG+I T+ + +E +
Sbjct: 167 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 226
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDG 246
F KE H L R G+ ++ A ++FL S AS + G ++ V G
Sbjct: 227 F----KEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAG 266
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 110 bits (264), Expect = 5e-24
Identities = 72/247 (29%), Positives = 124/247 (50%), Gaps = 7/247 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 62
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 31 ANKVALATASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 90
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 121
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 91 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 150
Query: 122 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG
Sbjct: 211 APGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGE 266
Query: 241 SVPVDGG 247
+V V GG
Sbjct: 267 TVVVGGG 273
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 110 bits (264), Expect = 5e-24
Identities = 68/224 (30%), Positives = 118/224 (52%), Gaps = 6/224 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 84 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 175
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+ YN+SK ++ TR +ALELAPK +RVNCV PG+I T+ + +E +
Sbjct: 176 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 235
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDG 246
F KE H L R G+ ++ A ++FL S AS + G ++ V G
Sbjct: 236 F----KEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAG 275
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 109 bits (263), Expect = 7e-24
Identities = 72/247 (29%), Positives = 124/247 (50%), Gaps = 7/247 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 62
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 90
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 121
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 91 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 150
Query: 122 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG
Sbjct: 211 APGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGE 266
Query: 241 SVPVDGG 247
+V V GG
Sbjct: 267 TVVVGGG 273
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 109 bits (263), Expect = 7e-24
Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 5/246 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
+AGKVV GA++ + ++ + + ++ + I D+
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE---LPGAVFILCDV 63
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTM 121
T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Y LT
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 122 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVRVNC++
Sbjct: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG I T L A + LGR G+P EV A FLAS+ A+ TG
Sbjct: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIE 242
Query: 242 VPVDGG 247
+ V GG
Sbjct: 243 LLVTGG 248
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 109 bits (263), Expect = 7e-24
Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 5/246 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
+AGKVV GA++ + ++ + + ++ + I D+
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE---LPGAVFILCDV 63
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTM 121
T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Y LT
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 122 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVRVNC++
Sbjct: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG I T L A + LGR G+P EV A FLAS+ A+ TG
Sbjct: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIE 242
Query: 242 VPVDGG 247
+ V GG
Sbjct: 243 LLVTGG 248
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 109 bits (263), Expect = 7e-24
Identities = 72/247 (29%), Positives = 124/247 (50%), Gaps = 7/247 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 62
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 90
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 121
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 91 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 150
Query: 122 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG
Sbjct: 211 APGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGE 266
Query: 241 SVPVDGG 247
+V V GG
Sbjct: 267 TVVVGGG 273
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 109 bits (263), Expect = 7e-24
Identities = 72/247 (29%), Positives = 124/247 (50%), Gaps = 7/247 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 62
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 90
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 121
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 91 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 150
Query: 122 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG
Sbjct: 211 APGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGE 266
Query: 241 SVPVDGG 247
+V V GG
Sbjct: 267 TVVVGGG 273
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 109 bits (263), Expect = 7e-24
Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 5/246 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
+AGKVV GA++ + ++ + + ++ + I D+
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE---LPGAVFILCDV 63
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTM 121
T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Y LT
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 122 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVRVNC++
Sbjct: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG I T L A + LGR G+P EV A FLAS+ A+ TG
Sbjct: 184 PGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIE 242
Query: 242 VPVDGG 247
+ V GG
Sbjct: 243 LLVTGG 248
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 109 bits (263), Expect = 7e-24
Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 5/246 (2%)
Query: 3 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 62
+AGKVV GA++ + ++ + + ++ + I D+
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE---LPGAVFILCDV 63
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTM 121
T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Y LT
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 122 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVRVNC++
Sbjct: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183
Query: 182 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 241
PG I T L A + LGR G+P EV A FLAS+ A+ TG
Sbjct: 184 PGNIWTPLWEELAALMPDPRASIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIE 242
Query: 242 VPVDGG 247
+ V GG
Sbjct: 243 LLVTGG 248
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 109 bits (263), Expect = 7e-24
Identities = 72/247 (29%), Positives = 124/247 (50%), Gaps = 7/247 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 62
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 13 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 72
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 121
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 73 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 132
Query: 122 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 133 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 192
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG
Sbjct: 193 APGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGE 248
Query: 241 SVPVDGG 247
+V V GG
Sbjct: 249 TVVVGGG 255
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 109 bits (261), Expect = 1e-23
Identities = 72/247 (29%), Positives = 124/247 (50%), Gaps = 7/247 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 62
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCMV 90
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 121
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 91 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 150
Query: 122 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG
Sbjct: 211 APGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGE 266
Query: 241 SVPVDGG 247
+V V GG
Sbjct: 267 TVVVGGG 273
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 109 bits (261), Expect = 1e-23
Identities = 71/247 (28%), Positives = 124/247 (50%), Gaps = 7/247 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 62
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 13 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 72
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 121
K D E+++ + +G +D+LV+NA + G++ + + +D+ ++ NV++ +T
Sbjct: 73 GKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTK 132
Query: 122 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 180
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 133 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 192
Query: 181 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGA 240
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG
Sbjct: 193 APGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGE 248
Query: 241 SVPVDGG 247
+V V GG
Sbjct: 249 TVVVGGG 255
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 108 bits (259), Expect = 2e-23
Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 8/230 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 78
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 79 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 138
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 157
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 198
FP + ++A V T+ +ALE A G+R+NCV PGVI ++ S
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWG 217
Query: 199 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
Q +F E + + R G P+EV++ + FL S AS ITG SV VDGGR
Sbjct: 218 Q--SFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGR 265
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 108 bits (259), Expect = 2e-23
Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 8/230 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 78
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 79 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 138
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 157
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 198
FP + ++A V T+ +ALE A G+R+NCV PGVI ++ S
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWG 217
Query: 199 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
Q +F E + + R G P+EV++ + FL S AS ITG SV VDGGR
Sbjct: 218 Q--SFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGR 265
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 108 bits (259), Expect = 2e-23
Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 8/230 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 78
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 57 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 116
Query: 79 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 138
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 117 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 176
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 198
FP + ++A V T+ +ALE A G+R+NCV PGVI ++ S
Sbjct: 177 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWG 236
Query: 199 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
Q +F E + + R G P+EV++ + FL S AS ITG SV VDGGR
Sbjct: 237 Q--SFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGR 284
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 108 bits (259), Expect = 2e-23
Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 8/230 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 78
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 79 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 138
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 157
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 198
FP + ++A V T+ +ALE A G+R+NCV PGVI ++ S
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWG 217
Query: 199 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
Q +F E + + R G P+EV++ + FL S AS ITG SV VDGGR
Sbjct: 218 Q--SFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGR 265
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 107 bits (258), Expect = 3e-23
Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 8/230 (3%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 78
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 79 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 138
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLRTNLTGSFYMCKAVYSSWMKEHGGSIVNI 157
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 198
FP + ++A V T+ +ALE A G+R+NCV PGVI ++ S
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWG 217
Query: 199 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
Q +F E + + R G P+EV++ + FL S AS ITG SV VDGGR
Sbjct: 218 Q--SFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGR 265
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 107 bits (257), Expect = 4e-23
Identities = 67/224 (29%), Positives = 118/224 (52%), Gaps = 6/224 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 84 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPAPLLSQLLPYMENRRGAVILVSSVAA 175
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+ Y++SK ++ TR +ALELAPK +RVNCV PG+I T+ + +E +
Sbjct: 176 YNPVVALGVYSVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 235
Query: 203 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDG 246
F KE H L R G+ ++ A ++FL S AS + G ++ V G
Sbjct: 236 F----KEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAG 275
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 98.7 bits (235), Expect = 2e-20
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 18/249 (7%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 125 PHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
P +L K ++ Y+ +KA+V T+ VA + +G+R NCV P
Sbjct: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177
Query: 183 GVILT-ELQRR---GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
G + T LQ R G EE FL+R K GR +E+A +LASD ++ +T
Sbjct: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQK----TGRFATAEEIAMLCVYLASDESTYVT 233
Query: 239 GASVPVDGG 247
G V +DGG
Sbjct: 234 GNPVIIDGG 242
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 98.7 bits (235), Expect = 2e-20
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 18/249 (7%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 125 PHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
P +L K ++ Y+ +KA+V T+ VA + +G+R NCV P
Sbjct: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177
Query: 183 GVILT-ELQRR---GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
G + T LQ R G EE FL+R K GR +E+A +LASD ++ +T
Sbjct: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQK----TGRFATAEEIAMLCVYLASDESAYVT 233
Query: 239 GASVPVDGG 247
G V +DGG
Sbjct: 234 GNPVIIDGG 242
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 98.7 bits (235), Expect = 2e-20
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 18/249 (7%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 125 PHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
P +L K ++ Y+ +KA+V T+ VA + +G+R NCV P
Sbjct: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177
Query: 183 GVILT-ELQRR---GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
G + T LQ R G EE FL+R K GR +E+A +LASD ++ +T
Sbjct: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQK----TGRFATAEEIAMLCVYLASDESAYVT 233
Query: 239 GASVPVDGG 247
G V +DGG
Sbjct: 234 GNPVIIDGG 242
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 97.5 bits (232), Expect = 4e-20
Identities = 72/249 (28%), Positives = 115/249 (46%), Gaps = 18/249 (7%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 125 PHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
P +L K ++ Y+ +KA+V T+ +A + +G+R NCV P
Sbjct: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSLAADFIQQGIRCNCVCP 177
Query: 183 GVILT-ELQRR---GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 238
G + T LQ R G EE FL+R K GR +E+A +LASD ++ +T
Sbjct: 178 GTVDTPSLQERIQARGNPEEARNDFLKRQK----TGRFATAEEIAMLCVYLASDESAYVT 233
Query: 239 GASVPVDGG 247
G V +DGG
Sbjct: 234 GNPVIIDGG 242
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 90.6 bits (215), Expect = 5e-18
Identities = 51/169 (30%), Positives = 91/169 (53%), Gaps = 2/169 (1%)
Query: 25 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 84 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 175
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 191
+ YN+SK ++ TR +ALELAPK +RVNCV PG+I T+ +
Sbjct: 176 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSK 224
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 87.0 bits (206), Expect = 6e-17
Identities = 57/164 (34%), Positives = 89/164 (54%), Gaps = 10/164 (6%)
Query: 90 GIIETGTIENTSLAQ-YDRLMNT----NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 144
G+ TGT+ + A+ +RL+ T NV++ +T VP + + G
Sbjct: 80 GLSVTGTVCHVGKAEDRERLVATTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAF 139
Query: 145 S-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 203
S PG YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T R + +E+
Sbjct: 140 SPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE--- 196
Query: 204 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E KET + R G+P++ A ++FL S+ AS ITG +V V GG
Sbjct: 197 -ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 239
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 86.6 bits (205), Expect = 7e-17
Identities = 63/224 (28%), Positives = 108/224 (48%), Gaps = 14/224 (6%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
+++ G +L++ RN+E + + D L+ + D+ KE D++ ++ H G+++
Sbjct: 22 MARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNF 79
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVN AGI G + T ++TN+ A+ +++ + G G+
Sbjct: 80 LVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL 139
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 203
+ G Y+ SK + F+R +A E+A K +RVN V PG + T++ + L E
Sbjct: 140 KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTK--DLKE------ 191
Query: 204 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E K+ LGR G+ EVA + FL + ITG + VDGG
Sbjct: 192 -EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 86.6 bits (205), Expect = 7e-17
Identities = 63/224 (28%), Positives = 108/224 (48%), Gaps = 14/224 (6%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
+++ G +L++ RN+E + + D L+ + D+ KE D++ ++ H G+++
Sbjct: 22 MARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNF 79
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVN AGI G + T ++TN+ A+ +++ + G G+
Sbjct: 80 LVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL 139
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 203
+ G Y+ SK + F+R +A E+A K +RVN V PG + T++ + L E
Sbjct: 140 KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTK--DLKE------ 191
Query: 204 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E K+ LGR G+ EVA + FL + ITG + VDGG
Sbjct: 192 -EHLKKNIPLGRFGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 80.2 bits (189), Expect = 6e-15
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 7/172 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 79
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 70 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 129
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 138
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
GI S P + Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 80.2 bits (189), Expect = 6e-15
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 7/172 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 79
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 70 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 129
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 138
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
GI S P + Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 80.2 bits (189), Expect = 6e-15
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 7/172 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 79
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 20 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 79
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 138
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 80 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 139
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
GI S P + Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 140 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 191
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 80.2 bits (189), Expect = 6e-15
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 7/172 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 79
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 70 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 129
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 138
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
GI S P + Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 80.2 bits (189), Expect = 6e-15
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 7/172 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 79
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 20 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 79
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 138
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 80 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 139
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
GI S P + Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 140 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 191
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/218 (24%), Positives = 94/218 (43%), Gaps = 6/218 (2%)
Query: 32 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 91
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 92 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 149
+ +DR N+R++ ++ +A L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIAARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 150 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 209
Y +K ++D T+ +ALEL P +RVN VNP V++T + + + L R
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI-- 204
Query: 210 THALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 205 --PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 77.8 bits (183), Expect = 3e-14
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 32 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 91
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 92 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 149
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 150 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 209
Y +K ++D T+ +ALEL P +RVN VNP V++T + + + L R
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI-- 204
Query: 210 THALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 205 --PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 77.8 bits (183), Expect = 3e-14
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 32 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 91
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 26 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 85
Query: 92 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 149
+ +DR N+R++ ++ + L+ G R+
Sbjct: 86 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 145
Query: 150 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 209
Y +K ++D T+ +ALEL P +RVN VNP V++T + + + L R
Sbjct: 146 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI-- 203
Query: 210 THALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 204 --PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 239
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 77.8 bits (183), Expect = 3e-14
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 32 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 91
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 92 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 149
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 150 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 209
Y +K ++D T+ +ALEL P +RVN VNP V++T + + + L R
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI-- 204
Query: 210 THALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 205 --PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 77.8 bits (183), Expect = 3e-14
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 32 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 91
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 92 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 149
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 150 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 209
Y +K ++D T+ +ALEL P +RVN VNP V++T + + + L R
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI-- 204
Query: 210 THALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 205 --PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 77.8 bits (183), Expect = 3e-14
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 32 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 91
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 92 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 149
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 150 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 209
Y +K ++D T+ +ALEL P +RVN VNP V++T + + + L R
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI-- 204
Query: 210 THALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 205 --PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 77.8 bits (183), Expect = 3e-14
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 32 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 91
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 92 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 149
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 150 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 209
Y +K ++D T+ +ALEL P +RVN VNP V++T + + + L R
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI-- 204
Query: 210 THALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 205 --PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 77.8 bits (183), Expect = 3e-14
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 32 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 91
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 92 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 149
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 150 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 209
Y +K ++D T+ +ALEL P +RVN VNP V++T + + + L R
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI-- 204
Query: 210 THALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 205 --PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 77.8 bits (183), Expect = 3e-14
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 6/218 (2%)
Query: 32 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 91
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 92 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 149
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 150 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 209
Y +K ++D T+ +ALEL P +RVN VNP V++T + + + L R
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI-- 204
Query: 210 THALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 205 --PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 72.1 bits (169), Expect = 2e-12
Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 9/196 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 81
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 81 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 140
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 140
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 141 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 200
Query: 141 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSE-EQ 199
G S P AY SK + F C+ E+ + V ++PG I T L ++ +
Sbjct: 201 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSR 260
Query: 200 YAAFLERTKETHALGR 215
Y T + AL R
Sbjct: 261 YGVMDTTTAQAEALWR 276
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 70.9 bits (166), Expect = 4e-12
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 81
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 76 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 135
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 140
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 136 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 195
Query: 141 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G S P AY SK + F C+ E+ + V ++PG I T L
Sbjct: 196 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 244
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 70.9 bits (166), Expect = 4e-12
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 81
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 76 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 135
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 140
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 136 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 195
Query: 141 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G S P AY SK + F C+ E+ + V ++PG I T L
Sbjct: 196 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 244
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 70.9 bits (166), Expect = 4e-12
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 81
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 76 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 135
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 140
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 136 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 195
Query: 141 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G S P AY SK + F C+ E+ + V ++PG I T L
Sbjct: 196 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 244
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 70.9 bits (166), Expect = 4e-12
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Query: 29 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 81
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 61 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 120
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 140
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 121 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 180
Query: 141 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G S P AY SK + F C+ E+ + V ++PG I T L
Sbjct: 181 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 229
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 70.5 bits (165), Expect = 5e-12
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 8/166 (4%)
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 141
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 70.5 bits (165), Expect = 5e-12
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 8/166 (4%)
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 141
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 70.5 bits (165), Expect = 5e-12
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 8/166 (4%)
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 141
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 70.5 bits (165), Expect = 5e-12
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 8/166 (4%)
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 141
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 70.5 bits (165), Expect = 5e-12
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 8/166 (4%)
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 141
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL645940-11|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 70.5 bits (165), Expect = 5e-12
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 8/166 (4%)
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 141
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 70.5 bits (165), Expect = 5e-12
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 8/166 (4%)
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 141
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 70.1 bits (164), Expect = 7e-12
Identities = 42/160 (26%), Positives = 78/160 (48%), Gaps = 3/160 (1%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
+++ G +L++ RN+E + + D L+ + D+ KE D++ ++ H G+++
Sbjct: 22 MARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNF 79
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVN AGI G + T ++TN+ A+ +++ + G G+
Sbjct: 80 LVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL 139
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 183
+ G Y+ SK + F+R +A E+A K +RVN V PG
Sbjct: 140 KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 67.7 bits (158), Expect = 4e-11
Identities = 49/166 (29%), Positives = 79/166 (47%), Gaps = 8/166 (4%)
Query: 84 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 141
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 97 VVVSCAGITQDEFLLHMSRDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 156
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 201
G G Y SKA V T+ A EL G+ N V PG I T + ++
Sbjct: 157 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIPCNSVLPGFIATPMTKKVPKK----- 211
Query: 202 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 212 -VVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 256
>CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein.
Length = 157
Score = 67.7 bits (158), Expect = 4e-11
Identities = 41/103 (39%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Query: 146 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 205
FP + ++A V T+ +ALE A G+R+NCV PGVI ++ S Q +F E
Sbjct: 19 FPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQ--SFFE 76
Query: 206 RTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 248
+ + R G P+EV++ + FL AS ITG SV VDGGR
Sbjct: 77 GSFQKIPAKRIGVPEEVSSVVCFLLPPAASFITGQSVDVDGGR 119
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 66.9 bits (156), Expect = 6e-11
Identities = 60/255 (23%), Positives = 103/255 (40%), Gaps = 9/255 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 59
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 120 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 177
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 178 NCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
N + PG I T +G S + F + GR G +E+A AFL SD AS
Sbjct: 236 NVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASW 291
Query: 237 ITGASVPVDGGRHAM 251
I GA + DGG +
Sbjct: 292 INGAVIKFDGGEEVL 306
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 66.9 bits (156), Expect = 6e-11
Identities = 60/255 (23%), Positives = 103/255 (40%), Gaps = 9/255 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 59
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 120 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 177
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 178 NCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
N + PG I T +G S + F + GR G +E+A AFL SD AS
Sbjct: 236 NVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASW 291
Query: 237 ITGASVPVDGGRHAM 251
I GA + DGG +
Sbjct: 292 INGAVIKFDGGEEVL 306
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 66.9 bits (156), Expect = 6e-11
Identities = 60/255 (23%), Positives = 103/255 (40%), Gaps = 9/255 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 59
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 120 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 177
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 178 NCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
N + PG I T +G S + F + GR G +E+A AFL SD AS
Sbjct: 236 NVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASW 291
Query: 237 ITGASVPVDGGRHAM 251
I GA + DGG +
Sbjct: 292 INGAVIKFDGGEEVL 306
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 66.9 bits (156), Expect = 6e-11
Identities = 60/255 (23%), Positives = 103/255 (40%), Gaps = 9/255 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 59
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 120 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 177
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 178 NCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
N + PG I T +G S + F + GR G +E+A AFL SD AS
Sbjct: 236 NVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASW 291
Query: 237 ITGASVPVDGGRHAM 251
I GA + DGG +
Sbjct: 292 INGAVIKFDGGEEVL 306
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 66.9 bits (156), Expect = 6e-11
Identities = 60/255 (23%), Positives = 103/255 (40%), Gaps = 9/255 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 59
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 120 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 177
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 178 NCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
N + PG I T +G S + F + GR G +E+A AFL SD AS
Sbjct: 236 NVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASW 291
Query: 237 ITGASVPVDGGRHAM 251
I GA + DGG +
Sbjct: 292 INGAVIKFDGGEEVL 306
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 64.5 bits (150), Expect = 3e-10
Identities = 60/220 (27%), Positives = 102/220 (46%), Gaps = 11/220 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDC-DKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 82
L+K G ++ L R+ + L +VS + +KF T +I D E +KI KT ++
Sbjct: 70 LAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKI--KTGLAGLEI 127
Query: 83 DVLVNNAGIIETGTIENTSLAQYD----RLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXX 137
+LVNN G+ + D +++N N+ S+ +T L +P ++E SKG
Sbjct: 128 GILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNI 187
Query: 138 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ--RRGGL 195
G+ P + Y+ +K VD F++C+ E KGV V V P + T+L R+ L
Sbjct: 188 SSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTL 247
Query: 196 SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 235
+ F++ +T L + A + + S+L S
Sbjct: 248 DKPSPETFVKSAIKTVGLQSRTNGYLIHALMGLIISNLPS 287
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 64.1 bits (149), Expect = 5e-10
Identities = 39/155 (25%), Positives = 78/155 (50%), Gaps = 3/155 (1%)
Query: 30 AQLSLTGRNVENL-QKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 88
A + ++ R +N+ Q V+ + S + K D E+++ + +G +D+LV+N
Sbjct: 55 AHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKLHGGIDILVSN 114
Query: 89 AGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS-F 146
A + G++ + + +D+ ++ NV++ +T VP + + G S
Sbjct: 115 AAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPS 174
Query: 147 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 181
PG YN+SK ++ +A+ELAP+ +RVNC++
Sbjct: 175 PGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCLH 209
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 63.7 bits (148), Expect = 6e-10
Identities = 51/174 (29%), Positives = 85/174 (48%), Gaps = 9/174 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDC-DKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 82
L+K G ++ L R+ + L +VS + +KF T +I D E +KI KT ++
Sbjct: 70 LAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKI--KTGLAGLEI 127
Query: 83 DVLVNNAGIIETGTIENTSLAQYD----RLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXX 137
+LVNN G+ + D +++N N+ S+ +T L +P ++E SKG
Sbjct: 128 GILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNI 187
Query: 138 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 191
G+ P + Y+ +K VD F++C+ E KGV V V P + T+L +
Sbjct: 188 SSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAK 241
>BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein.
Length = 244
Score = 63.7 bits (148), Expect = 6e-10
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 8/195 (4%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 33 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 92
Query: 116 IYYLT-MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 174
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 93 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 152
Query: 175 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 232
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 153 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 207
Query: 233 LASNITGASVPVDGG 247
LAS +TGA + DGG
Sbjct: 208 LASYVTGAVLVADGG 222
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 63.7 bits (148), Expect = 6e-10
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 8/195 (4%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 116 IYYLT-MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 174
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200
Query: 175 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 232
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 201 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255
Query: 233 LASNITGASVPVDGG 247
LAS +TGA + DGG
Sbjct: 256 LASYVTGAVLVADGG 270
>AL023881-2|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 63.7 bits (148), Expect = 6e-10
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 8/195 (4%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 116 IYYLT-MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 174
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200
Query: 175 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 232
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 201 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255
Query: 233 LASNITGASVPVDGG 247
LAS +TGA + DGG
Sbjct: 256 LASYVTGAVLVADGG 270
>AL023881-1|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 63.7 bits (148), Expect = 6e-10
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 8/195 (4%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 69 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 128
Query: 116 IYYLT-MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 174
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 129 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 188
Query: 175 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 232
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 189 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 243
Query: 233 LASNITGASVPVDGG 247
LAS +TGA + DGG
Sbjct: 244 LASYVTGAVLVADGG 258
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 63.7 bits (148), Expect = 6e-10
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 8/195 (4%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 116 IYYLT-MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 174
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200
Query: 175 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 232
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 201 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255
Query: 233 LASNITGASVPVDGG 247
LAS +TGA + DGG
Sbjct: 256 LASYVTGAVLVADGG 270
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 63.7 bits (148), Expect = 6e-10
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 8/195 (4%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 116 IYYLT-MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 174
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200
Query: 175 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 232
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 201 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255
Query: 233 LASNITGASVPVDGG 247
LAS +TGA + DGG
Sbjct: 256 LASYVTGAVLVADGG 270
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 62.9 bits (146), Expect = 1e-09
Identities = 52/207 (25%), Positives = 94/207 (45%), Gaps = 13/207 (6%)
Query: 27 KLGAQLSLTGRNVENLQKVSKDCDKFAST-----LSITADLTKE-SDIEKIIKKTIDHYG 80
K GA ++L RN + L + K+ + + L I+ D++++ + +E +IK+ + G
Sbjct: 54 KQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLG 113
Query: 81 KLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXX 139
+D+LVN AG+ +G E+ ++ ++RLM+ N Y + + + E + G
Sbjct: 114 PVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSS 173
Query: 140 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 199
G G AY+ SK ++ + +E+ P V + P T G +EE
Sbjct: 174 QAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTP-----GFAEEN 228
Query: 200 YAAFLERTKETHALGRPGKPDEVAATI 226
LE T+ KP++VA I
Sbjct: 229 RTKPLE-TRLISETTSVCKPEQVAKQI 254
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 62.9 bits (146), Expect = 1e-09
Identities = 58/251 (23%), Positives = 101/251 (40%), Gaps = 9/251 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 59
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 120 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 177
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 178 NCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 236
N + PG I T +G S + F + GR G +E+A AFL S AS
Sbjct: 236 NVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSGYASW 291
Query: 237 ITGASVPVDGG 247
+ GA + DGG
Sbjct: 292 VNGAVIKFDGG 302
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 62.9 bits (146), Expect = 1e-09
Identities = 52/207 (25%), Positives = 94/207 (45%), Gaps = 13/207 (6%)
Query: 27 KLGAQLSLTGRNVENLQKVSKDCDKFAST-----LSITADLTKE-SDIEKIIKKTIDHYG 80
K GA ++L RN + L + K+ + + L I+ D++++ + +E +IK+ + G
Sbjct: 54 KQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLG 113
Query: 81 KLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXX 139
+D+LVN AG+ +G E+ ++ ++RLM+ N Y + + + E + G
Sbjct: 114 PVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSS 173
Query: 140 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 199
G G AY+ SK ++ + +E+ P V + P T G +EE
Sbjct: 174 QAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTP-----GFAEEN 228
Query: 200 YAAFLERTKETHALGRPGKPDEVAATI 226
LE T+ KP++VA I
Sbjct: 229 RTKPLE-TRLISETTSVCKPEQVAKQI 254
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 62.9 bits (146), Expect = 1e-09
Identities = 52/207 (25%), Positives = 94/207 (45%), Gaps = 13/207 (6%)
Query: 27 KLGAQLSLTGRNVENLQKVSKDCDKFAST-----LSITADLTKE-SDIEKIIKKTIDHYG 80
K GA ++L RN + L + K+ + + L I+ D++++ + +E +IK+ + G
Sbjct: 54 KQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLG 113
Query: 81 KLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXX 139
+D+LVN AG+ +G E+ ++ ++RLM+ N Y + + + E + G
Sbjct: 114 PVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSS 173
Query: 140 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 199
G G AY+ SK ++ + +E+ P V + P T G +EE
Sbjct: 174 QAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTP-----GFAEEN 228
Query: 200 YAAFLERTKETHALGRPGKPDEVAATI 226
LE T+ KP++VA I
Sbjct: 229 RTKPLE-TRLISETTSVCKPEQVAKQI 254
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 117
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 118 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 178 NCVNPGVILTELQRRGGLSEEQ 199
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 117
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 118 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 178 NCVNPGVILTELQRRGGLSEEQ 199
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 117
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 118 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 178 NCVNPGVILTELQRRGGLSEEQ 199
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 82
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 83 DVLVNNA--GIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 135
DVLVNNA G+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 136 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 195
G + + Y + KA+ D+ A EL GV + PG++ TEL +
Sbjct: 147 VVISSPGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMA 206
Query: 196 SEE 198
EE
Sbjct: 207 KEE 209
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 82
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 83 DVLVNNA--GIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 135
DVLVNNA G+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 136 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 195
G + + Y + KA+ D+ A EL GV + PG++ TEL +
Sbjct: 147 VVISSPGSLQYMFNVLYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMA 206
Query: 196 SEE 198
EE
Sbjct: 207 KEE 209
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 82
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 83 DVLVNNA--GIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 135
DVLVNNA G+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 136 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 195
G + + Y + KA+ D+ A EL GV + PG++ TEL +
Sbjct: 147 VVISSPGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMA 206
Query: 196 SEE 198
EE
Sbjct: 207 KEE 209
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 82
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 83 DVLVNNA--GIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 135
DVLVNNA G+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 136 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 195
G + + Y + KA+ D+ A EL GV + PG++ TEL +
Sbjct: 147 VVISSPGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMA 206
Query: 196 SEE 198
EE
Sbjct: 207 KEE 209
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 61.7 bits (143), Expect = 2e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 117
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRLLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 118 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 178 NCVNPGVILTELQRRGGLSEEQ 199
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 61.7 bits (143), Expect = 2e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 144
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 145 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 183
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 84
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 187
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 84
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 187
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 61.7 bits (143), Expect = 2e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 144
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 145 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 183
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 84
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 187
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 84
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 187
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 61.7 bits (143), Expect = 2e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 144
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 145 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 183
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 61.7 bits (143), Expect = 2e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 144
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 145 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 183
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 84
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 187
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 84
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 187
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 84
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 187
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 61.7 bits (143), Expect = 2e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 84
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 187
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 61.3 bits (142), Expect = 3e-09
Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 8/171 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 82
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 138
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
+ P + A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 61.3 bits (142), Expect = 3e-09
Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 8/171 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 82
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 66 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 124
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 138
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 125 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 183
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
+ P + A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 184 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 234
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 61.3 bits (142), Expect = 3e-09
Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 8/171 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 82
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 138
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
+ P + A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 61.3 bits (142), Expect = 3e-09
Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 8/171 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 82
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 66 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 124
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 138
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 125 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 183
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
+ P + A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 184 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 234
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 60.9 bits (141), Expect = 4e-09
Identities = 46/142 (32%), Positives = 64/142 (45%), Gaps = 3/142 (2%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 117
DLTK DI + ++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRFLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 118 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 178 NCVNPGVILTELQRRGGLSEEQ 199
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 60.1 bits (139), Expect = 7e-09
Identities = 62/260 (23%), Positives = 103/260 (39%), Gaps = 19/260 (7%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 57
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLF 60
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+ S+
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112
Query: 118 YLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL--ELA 171
T L + ++ + G G+ Y SK + FTR AL L
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEE--QYAAFLERTKETHALGRPGKPDEVAATIAFL 229
GVR+N + PG + T + E QY + + K+ P +A + L
Sbjct: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232
Query: 230 ASDLASNITGASVPVDGGRH 249
D A N + G H
Sbjct: 233 IEDDALNGAIMKITTSKGIH 252
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 60.1 bits (139), Expect = 7e-09
Identities = 62/260 (23%), Positives = 103/260 (39%), Gaps = 19/260 (7%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 57
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLF 60
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+ S+
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112
Query: 118 YLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL--ELA 171
T L + ++ + G G+ Y SK + FTR AL L
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEE--QYAAFLERTKETHALGRPGKPDEVAATIAFL 229
GVR+N + PG + T + E QY + + K+ P +A + L
Sbjct: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232
Query: 230 ASDLASNITGASVPVDGGRH 249
D A N + G H
Sbjct: 233 IEDDALNGAIMKITTSKGIH 252
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 60.1 bits (139), Expect = 7e-09
Identities = 62/260 (23%), Positives = 103/260 (39%), Gaps = 19/260 (7%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 57
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+ S+
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112
Query: 118 YLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL--ELA 171
T L + ++ + G G+ Y SK + FTR AL L
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEE--QYAAFLERTKETHALGRPGKPDEVAATIAFL 229
GVR+N + PG + T + E QY + + K+ P +A + L
Sbjct: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232
Query: 230 ASDLASNITGASVPVDGGRH 249
D A N + G H
Sbjct: 233 IEDDALNGAIMKITTSKGIH 252
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 60.1 bits (139), Expect = 7e-09
Identities = 47/171 (27%), Positives = 82/171 (47%), Gaps = 8/171 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 82
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 138
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
+ P + A++ S+A +D F+R + E A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 60.1 bits (139), Expect = 7e-09
Identities = 47/171 (27%), Positives = 82/171 (47%), Gaps = 8/171 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 82
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 138
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
+ P + A++ S+A +D F+R + E A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 60.1 bits (139), Expect = 7e-09
Identities = 62/260 (23%), Positives = 103/260 (39%), Gaps = 19/260 (7%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 57
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 117
I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+ S+
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112
Query: 118 YLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL--ELA 171
T L + ++ + G G+ Y SK + FTR AL L
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172
Query: 172 PKGVRVNCVNPGVILTELQRRGGLSEE--QYAAFLERTKETHALGRPGKPDEVAATIAFL 229
GVR+N + PG + T + E QY + + K+ P +A + L
Sbjct: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232
Query: 230 ASDLASNITGASVPVDGGRH 249
D A N + G H
Sbjct: 233 IEDDALNGAIMKITTSKGIH 252
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 59.7 bits (138), Expect = 1e-08
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 6/189 (3%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADL 62
GK V L+K+GA + +T R+ E LQKV C + AS I +
Sbjct: 34 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ E+ + + G LD+L+ N + + + + + M N S LT+
Sbjct: 94 EDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153
Query: 123 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN---C 179
A+P L +S G G ++P V AY+ SK ++D F + E + V V+ C
Sbjct: 154 ALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLC 213
Query: 180 VNPGVILTE 188
V G+I TE
Sbjct: 214 V-LGLIDTE 221
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 59.7 bits (138), Expect = 1e-08
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 6/189 (3%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADL 62
GK V L+K+GA + +T R+ E LQKV C + AS I +
Sbjct: 34 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ E+ + + G LD+L+ N + + + + + M N S LT+
Sbjct: 94 EDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153
Query: 123 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN---C 179
A+P L +S G G ++P V AY+ SK ++D F + E + V V+ C
Sbjct: 154 ALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLC 213
Query: 180 VNPGVILTE 188
V G+I TE
Sbjct: 214 V-LGLIDTE 221
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 59.7 bits (138), Expect = 1e-08
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 6/189 (3%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADL 62
GK V L+K+GA + +T R+ E LQKV C + AS I +
Sbjct: 34 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ E+ + + G LD+L+ N + + + + + M N S LT+
Sbjct: 94 EDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153
Query: 123 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN---C 179
A+P L +S G G ++P V AY+ SK ++D F + E + V V+ C
Sbjct: 154 ALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLC 213
Query: 180 VNPGVILTE 188
V G+I TE
Sbjct: 214 V-LGLIDTE 221
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 59.7 bits (138), Expect = 1e-08
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 6/189 (3%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADL 62
GK V L+K+GA + +T R+ E LQKV C + AS I +
Sbjct: 34 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ E+ + + G LD+L+ N + + + + + M N S LT+
Sbjct: 94 EDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153
Query: 123 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN---C 179
A+P L +S G G ++P V AY+ SK ++D F + E + V V+ C
Sbjct: 154 ALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLC 213
Query: 180 VNPGVILTE 188
V G+I TE
Sbjct: 214 V-LGLIDTE 221
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 59.7 bits (138), Expect = 1e-08
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 6/189 (3%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADL 62
GK V L+K+GA + +T R+ E LQKV C + AS I +
Sbjct: 34 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ E+ + + G LD+L+ N + + + + + M N S LT+
Sbjct: 94 EDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153
Query: 123 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN---C 179
A+P L +S G G ++P V AY+ SK ++D F + E + V V+ C
Sbjct: 154 ALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLC 213
Query: 180 VNPGVILTE 188
V G+I TE
Sbjct: 214 V-LGLIDTE 221
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 59.3 bits (137), Expect = 1e-08
Identities = 47/164 (28%), Positives = 79/164 (48%), Gaps = 8/164 (4%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 82
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 138
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
+ P + A++ SKA +D F+R + E A KG+ V + P
Sbjct: 205 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIP 248
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 59.3 bits (137), Expect = 1e-08
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 84
+KL ++L L N L++ + C + + + D + DI K G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKNCKAEIGDVSI 116
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 187
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 3/159 (1%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
++ LG G+ KV ++ + D +E EK++K +D +G++DV
Sbjct: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEG--EKVVKTALDAFGRIDV 95
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
+VNNAGI+ + S +D + ++R + +T A H+ + K G GI
Sbjct: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
G Y+ +K + +A+E + N + P
Sbjct: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 3/159 (1%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
++ LG G+ KV ++ + D +E EK++K +D +G++DV
Sbjct: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEG--EKVVKTALDAFGRIDV 95
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
+VNNAGI+ + S +D + ++R + +T A H+ + K G GI
Sbjct: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
G Y+ +K + +A+E + N + P
Sbjct: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 56.4 bits (130), Expect = 9e-08
Identities = 53/218 (24%), Positives = 96/218 (44%), Gaps = 18/218 (8%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDK--FASTL-SITADLTKESDIEKIIKKTIDHYGK 81
L + G ++ R V N+++++ +C + TL DL+ E DI + +
Sbjct: 31 LVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSG 90
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXXXXXX 138
+D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 91 VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININ 150
Query: 139 XXXGIRSFPGVLA--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ-RRG 193
G R P + Y+ +K +V T + EL A +R C++PGV+ T+ +
Sbjct: 151 SMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLH 210
Query: 194 GLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
E+ AA E+ K KP++VA + ++ S
Sbjct: 211 DKDPEKAAATYEQMKCL-------KPEDVAEAVIYVLS 241
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 56.4 bits (130), Expect = 9e-08
Identities = 53/218 (24%), Positives = 96/218 (44%), Gaps = 18/218 (8%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDK--FASTL-SITADLTKESDIEKIIKKTIDHYGK 81
L + G ++ R V N+++++ +C + TL DL+ E DI + +
Sbjct: 31 LVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSG 90
Query: 82 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXXXXXX 138
+D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 91 VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININ 150
Query: 139 XXXGIRSFPGVLA--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ-RRG 193
G R P + Y+ +K +V T + EL A +R C++PGV+ T+ +
Sbjct: 151 SMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLH 210
Query: 194 GLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
E+ AA E+ K KP++VA + ++ S
Sbjct: 211 DKDPEKAAATYEQMKCL-------KPEDVAEAVIYVLS 241
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 3/159 (1%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 84
++ LG G+ KV ++ + D +E EK++K +D +G++DV
Sbjct: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEG--EKVVKTALDAFGRIDV 95
Query: 85 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 143
+VNNAGI+ + S +D + ++R + +T A H+ + K G GI
Sbjct: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
Query: 144 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 182
G Y+ +K + +A+E + N + P
Sbjct: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 3 protein.
Length = 310
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/173 (27%), Positives = 84/173 (48%), Gaps = 9/173 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKL 82
L+K G + L R +E L+ ++ + ++ S I AD TK+ DI + IK+ + ++
Sbjct: 68 LAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKD-DIYEHIKEKLAGL-EI 125
Query: 83 DVLVNNAGIIETGTIENTSLA--QYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX 140
+LVNN G++ + A + L++ N+ S+ +T L + H+ ES+
Sbjct: 126 GILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHM-ESRQKGLILNIS 184
Query: 141 XGIRSFPGVL--AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 191
GI FP L Y+ SKA V F++ + E K V + + P + T + +
Sbjct: 185 SGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTK 237
>CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein.
Length = 310
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/173 (27%), Positives = 84/173 (48%), Gaps = 9/173 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKL 82
L+K G + L R +E L+ ++ + ++ S I AD TK+ DI + IK+ + ++
Sbjct: 68 LAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKD-DIYEHIKEKLAGL-EI 125
Query: 83 DVLVNNAGIIETGTIENTSLA--QYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX 140
+LVNN G++ + A + L++ N+ S+ +T L + H+ ES+
Sbjct: 126 GILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHM-ESRQKGLILNIS 184
Query: 141 XGIRSFPGVL--AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 191
GI FP L Y+ SKA V F++ + E K V + + P + T + +
Sbjct: 185 SGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTK 237
>BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/173 (27%), Positives = 84/173 (48%), Gaps = 9/173 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKL 82
L+K G + L R +E L+ ++ + ++ S I AD TK+ DI + IK+ + ++
Sbjct: 68 LAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKD-DIYEHIKEKLAGL-EI 125
Query: 83 DVLVNNAGIIETGTIENTSLA--QYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX 140
+LVNN G++ + A + L++ N+ S+ +T L + H+ ES+
Sbjct: 126 GILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHM-ESRQKGLILNIS 184
Query: 141 XGIRSFPGVL--AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 191
GI FP L Y+ SKA V F++ + E K V + + P + T + +
Sbjct: 185 SGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTK 237
>AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/173 (27%), Positives = 84/173 (48%), Gaps = 9/173 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKL 82
L+K G + L R +E L+ ++ + ++ S I AD TK+ DI + IK+ + ++
Sbjct: 68 LAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKD-DIYEHIKEKLAGL-EI 125
Query: 83 DVLVNNAGIIETGTIENTSLA--QYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX 140
+LVNN G++ + A + L++ N+ S+ +T L + H+ ES+
Sbjct: 126 GILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHM-ESRQKGLILNIS 184
Query: 141 XGIRSFPGVL--AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 191
GI FP L Y+ SKA V F++ + E K V + + P + T + +
Sbjct: 185 SGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTK 237
>AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/173 (27%), Positives = 84/173 (48%), Gaps = 9/173 (5%)
Query: 25 LSKLGAQLSLTGRNVENLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKL 82
L+K G + L R +E L+ ++ + ++ S I AD TK+ DI + IK+ + ++
Sbjct: 68 LAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKD-DIYEHIKEKLAGL-EI 125
Query: 83 DVLVNNAGIIETGTIENTSLA--QYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX 140
+LVNN G++ + A + L++ N+ S+ +T L + H+ ES+
Sbjct: 126 GILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHM-ESRQKGLILNIS 184
Query: 141 XGIRSFPGVL--AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 191
GI FP L Y+ SKA V F++ + E K V + + P + T + +
Sbjct: 185 SGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTK 237
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 4/155 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLD 83
++LG+ L LT LQKV +C K + I AD+ E +++ +D G LD
Sbjct: 50 ARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLD 109
Query: 84 VLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
LV N+ G GT + A LM N S LT A+P L +SKG G
Sbjct: 110 YLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLG 168
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
Y+ +K ++D F + EL + V V
Sbjct: 169 RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 4/155 (2%)
Query: 26 SKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLD 83
++LG+ L LT LQKV +C K + I AD+ E +++ +D G LD
Sbjct: 50 ARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLD 109
Query: 84 VLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 142
LV N+ G GT + A LM N S LT A+P L +SKG G
Sbjct: 110 YLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLG 168
Query: 143 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
Y+ +K ++D F + EL + V V
Sbjct: 169 RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 53.2 bits (122), Expect = 8e-07
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Query: 24 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 78
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 79 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 137
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 138 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 53.2 bits (122), Expect = 8e-07
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Query: 24 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 78
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 79 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 137
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 138 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 53.2 bits (122), Expect = 8e-07
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Query: 24 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 78
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 79 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 137
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 138 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 53.2 bits (122), Expect = 8e-07
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Query: 24 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 78
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 79 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 137
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 138 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 53.2 bits (122), Expect = 8e-07
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Query: 24 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 78
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 79 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 137
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 138 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 53.2 bits (122), Expect = 8e-07
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 9/172 (5%)
Query: 24 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 78
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 79 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 137
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 138 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 189
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 52.4 bits (120), Expect = 1e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 116 IYYLTMLAVPHLLESK 131
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 52.4 bits (120), Expect = 1e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 116 IYYLTMLAVPHLLESK 131
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>AL162732-2|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 52.4 bits (120), Expect = 1e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Query: 56 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 115
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 116 IYYLTMLAVPHLLESK 131
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase, type II protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 167 ALELAPKGVRVNCVNPGVILTEL 189
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 167 ALELAPKGVRVNCVNPGVILTEL 189
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 167 ALELAPKGVRVNCVNPGVILTEL 189
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 167 ALELAPKGVRVNCVNPGVILTEL 189
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 167 ALELAPKGVRVNCVNPGVILTEL 189
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 52.0 bits (119), Expect = 2e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 13 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 72
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 73 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 132
Query: 167 ALELAPKGVRVNCVNPGVILTEL 189
A +LAP G+RV + PG+ T L
Sbjct: 133 ARDLAPIGIRVMTIAPGLFGTPL 155
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 167 ALELAPKGVRVNCVNPGVILTEL 189
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 167 ALELAPKGVRVNCVNPGVILTEL 189
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 167 ALELAPKGVRVNCVNPGVILTEL 189
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 125 PHLLESK 131
P +L K
Sbjct: 118 PKMLAQK 124
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 125 PHLLESK 131
P +L K
Sbjct: 118 PKMLAQK 124
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 64
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 65 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 124
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 125 PHLLESK 131
P +L K
Sbjct: 118 PKMLAQK 124
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 1/112 (0%)
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 138
G++DVLVNNAG+ G +E SLA + +TN L +P + + G
Sbjct: 82 GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVIS 141
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 190
G++ Y SK +++ F +A++L + ++ V PG ++TE +
Sbjct: 142 SVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVEPGPVVTEFE 193
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 50.8 bits (116), Expect = 5e-06
Identities = 36/132 (27%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Query: 107 RLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRC 165
+++N N+ S+ +T L +P ++E SKG G+ P + Y+ +K VD F++C
Sbjct: 21 KMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQC 80
Query: 166 VALELAPKGVRVNCVNPGVILTELQ--RRGGLSEEQYAAFLERTKETHALGRPGKPDEVA 223
+ E KGV V V P + T+L R+ L + F++ +T L +
Sbjct: 81 LHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIH 140
Query: 224 ATIAFLASDLAS 235
A + + S+L S
Sbjct: 141 ALMGLIISNLPS 152
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 50.0 bits (114), Expect = 8e-06
Identities = 37/189 (19%), Positives = 77/189 (40%), Gaps = 5/189 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADL 62
AG++V +K + L L N +++ + +C K T + D
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDC 94
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ +I + + + G + ++VNNAG + + +T + + N+ +++T
Sbjct: 95 SNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKA 154
Query: 123 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE---LAPKGVRVN 178
+P ++E + G G P ++ Y SK + F R + E L G++ +
Sbjct: 155 LLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTS 214
Query: 179 CVNPGVILT 187
C+ P + T
Sbjct: 215 CLCPVFVNT 223
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 50.0 bits (114), Expect = 8e-06
Identities = 37/189 (19%), Positives = 77/189 (40%), Gaps = 5/189 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADL 62
AG++V +K + L L N +++ + +C K T + D
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDC 94
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ +I + + + G + ++VNNAG + + +T + + N+ +++T
Sbjct: 95 SNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKA 154
Query: 123 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE---LAPKGVRVN 178
+P ++E + G G P ++ Y SK + F R + E L G++ +
Sbjct: 155 LLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTS 214
Query: 179 CVNPGVILT 187
C+ P + T
Sbjct: 215 CLCPVFVNT 223
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 50.0 bits (114), Expect = 8e-06
Identities = 37/189 (19%), Positives = 77/189 (40%), Gaps = 5/189 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADL 62
AG++V +K + L L N +++ + +C K T + D
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDC 94
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ +I + + + G + ++VNNAG + + +T + + N+ +++T
Sbjct: 95 SNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKA 154
Query: 123 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE---LAPKGVRVN 178
+P ++E + G G P ++ Y SK + F R + E L G++ +
Sbjct: 155 LLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTS 214
Query: 179 CVNPGVILT 187
C+ P + T
Sbjct: 215 CLCPVFVNT 223
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 50.0 bits (114), Expect = 8e-06
Identities = 37/189 (19%), Positives = 77/189 (40%), Gaps = 5/189 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADL 62
AG++V +K + L L N +++ + +C K T + D
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDC 94
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ +I + + + G + ++VNNAG + + +T + + N+ +++T
Sbjct: 95 SNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKA 154
Query: 123 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE---LAPKGVRVN 178
+P ++E + G G P ++ Y SK + F R + E L G++ +
Sbjct: 155 LLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTS 214
Query: 179 CVNPGVILT 187
C+ P + T
Sbjct: 215 CLCPVFVNT 223
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 50.0 bits (114), Expect = 8e-06
Identities = 37/189 (19%), Positives = 77/189 (40%), Gaps = 5/189 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADL 62
AG++V +K + L L N +++ + +C K T + D
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDC 94
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ +I + + + G + ++VNNAG + + +T + + N+ +++T
Sbjct: 95 SNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKA 154
Query: 123 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE---LAPKGVRVN 178
+P ++E + G G P ++ Y SK + F R + E L G++ +
Sbjct: 155 LLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTS 214
Query: 179 CVNPGVILT 187
C+ P + T
Sbjct: 215 CLCPVFVNT 223
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 50.0 bits (114), Expect = 8e-06
Identities = 37/189 (19%), Positives = 77/189 (40%), Gaps = 5/189 (2%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADL 62
AG++V +K + L L N +++ + +C K T + D
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDC 94
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 122
+ +I + + + G + ++VNNAG + + +T + + N+ +++T
Sbjct: 95 SNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKA 154
Query: 123 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE---LAPKGVRVN 178
+P ++E + G G P ++ Y SK + F R + E L G++ +
Sbjct: 155 LLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTS 214
Query: 179 CVNPGVILT 187
C+ P + T
Sbjct: 215 CLCPVFVNT 223
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 49.2 bits (112), Expect = 1e-05
Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 15/213 (7%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GK V L++ G + L R++E + +KD + A D
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLD 97
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYD----------RLM 109
L I + K I+ ++D+L+NNAG++ T E+ Q+ L+
Sbjct: 98 LASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLL 157
Query: 110 NTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE 169
+++ ++ + L G R + AY SK ++ FT+ ++
Sbjct: 158 LDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRR 217
Query: 170 LAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
L GV VN ++PGV TEL R G+ +++
Sbjct: 218 LQGSGVTVNALHPGVARTELGRHTGIHGSTFSS 250
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 105 YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFT 163
+D+ ++ NV++ +T VP + + G S PG YN+SK ++
Sbjct: 10 WDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLN 69
Query: 164 RCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
+A+ELAP+ +RVNC++ + L+ L G L E + A
Sbjct: 70 NTLAIELAPRNIRVNCLH--LDLSRLASAGWLGEPEDCA 106
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 48.0 bits (109), Expect = 3e-05
Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 5/180 (2%)
Query: 34 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 93
LT E+LQ+V+ + +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 94 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 152
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 153 NISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 212
+SK ++ F+ + ++A G+RV+ V PG T + L + A + T A
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 48.0 bits (109), Expect = 3e-05
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 6/174 (3%)
Query: 40 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGK--LDVLVNNAGI-IETGT 96
E QK+ +D T + D+TK I+ + D G+ L LVNNAG+ + +G
Sbjct: 60 EGSQKLQRDTSYRLQTTLL--DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGP 117
Query: 97 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISK 156
E + + +++N N+ + +T+ +P + ++G G + G Y +SK
Sbjct: 118 NEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG-GYCVSK 176
Query: 157 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 210
V+ F+ + EL GV+V + PG T + + L + +ET
Sbjct: 177 FGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQET 230
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 48.0 bits (109), Expect = 3e-05
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 6/174 (3%)
Query: 40 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGK--LDVLVNNAGI-IETGT 96
E QK+ +D T + D+TK I+ + D G+ L LVNNAG+ + +G
Sbjct: 60 EGSQKLQRDTSYRLQTTLL--DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGP 117
Query: 97 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISK 156
E + + +++N N+ + +T+ +P + ++G G + G Y +SK
Sbjct: 118 NEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG-GYCVSK 176
Query: 157 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 210
V+ F+ + EL GV+V + PG T + + L + +ET
Sbjct: 177 FGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQET 230
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 48.0 bits (109), Expect = 3e-05
Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 5/180 (2%)
Query: 34 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 93
LT E+LQ+V+ + +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 94 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 152
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 153 NISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 212
+SK ++ F+ + ++A G+RV+ V PG T + L + A + T A
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 48.0 bits (109), Expect = 3e-05
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 6/174 (3%)
Query: 40 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGK--LDVLVNNAGI-IETGT 96
E QK+ +D T + D+TK I+ + D G+ L LVNNAG+ + +G
Sbjct: 60 EGSQKLQRDTSYRLQTTLL--DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGP 117
Query: 97 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISK 156
E + + +++N N+ + +T+ +P + ++G G + G Y +SK
Sbjct: 118 NEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG-GYCVSK 176
Query: 157 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 210
V+ F+ + EL GV+V + PG T + + L + +ET
Sbjct: 177 FGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQET 230
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 48.0 bits (109), Expect = 3e-05
Identities = 48/213 (22%), Positives = 84/213 (39%), Gaps = 15/213 (7%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GK V L++ G + L R++E + +KD + A D
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLD 97
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYD----------RLM 109
L I K I+ ++D+L+NNAG++ T E+ Q+ L+
Sbjct: 98 LASLKSIRVFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLL 157
Query: 110 NTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE 169
+++ ++ + L G R + AY SK ++ FT+ ++
Sbjct: 158 LDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRR 217
Query: 170 LAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
L GV VN ++PGV TEL R G+ +++
Sbjct: 218 LQGSGVTVNALHPGVARTELGRHTGIHGSTFSS 250
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 48.0 bits (109), Expect = 3e-05
Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 5/180 (2%)
Query: 34 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 93
LT E+LQ+V+ + +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 94 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 152
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 153 NISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 212
+SK ++ F+ + ++A G+RV+ V PG T + L + A + T A
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 47.2 bits (107), Expect = 6e-05
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 57
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT 100
I D+ + + +K +DH+G+LD+LVNNAG+ E T
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNKKNWEKT 103
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 47.2 bits (107), Expect = 6e-05
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Query: 1 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 57
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 58 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT 100
I D+ + + +K +DH+G+LD+LVNNAG+ E T
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKT 103
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 46.8 bits (106), Expect = 7e-05
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 4/134 (2%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 113
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 114 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 173
+ +T+ +P + ++G G +F V Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 174 GVRVNCVNPGVILT 187
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 46.8 bits (106), Expect = 7e-05
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 4/134 (2%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 113
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 114 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 173
+ +T+ +P + ++G G +F V Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 174 GVRVNCVNPGVILT 187
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 46.8 bits (106), Expect = 7e-05
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 4/134 (2%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 113
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 114 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 173
+ +T+ +P + ++G G +F V Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 174 GVRVNCVNPGVILT 187
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 118
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 119 LTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL--APK-G 174
T +P +LE + G G+ S GV Y SK V F ++ EL A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 175 VRVNCVNPGVILTELQR 191
++ V P ++ T + R
Sbjct: 236 IKTTLVCPYLVDTGMFR 252
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 118
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 119 LTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL--APK-G 174
T +P +LE + G G+ S GV Y SK V F ++ EL A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 175 VRVNCVNPGVILTELQR 191
++ V P ++ T + R
Sbjct: 236 IKTTLVCPYLVDTGMFR 252
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Query: 59 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 118
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 119 LTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL--APK-G 174
T +P +LE + G G+ S GV Y SK V F ++ EL A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 175 VRVNCVNPGVILTELQR 191
++ V P ++ T + R
Sbjct: 236 IKTTLVCPYLVDTGMFR 252
>U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha
hydroxysteroid dehydrogenase protein.
Length = 317
Score = 45.2 bits (102), Expect = 2e-04
Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 4/134 (2%)
Query: 57 SITADLTKESDIEKIIKKTIDHYG--KLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNV 113
++T D+TK I + +H G +L LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRRLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 114 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 173
+ +T+ +P + ++G G F Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGKNCQCLQHSGKSCFL-CRGYCVSKYGVEAFSDILRREIQHF 197
Query: 174 GVRVNCVNPGVILT 187
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/180 (24%), Positives = 74/180 (41%), Gaps = 5/180 (2%)
Query: 34 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 93
LT E+LQ V+ F +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQGVASS--GFNTTLLDITDPQSFQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 94 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 152
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 153 NISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 212
+SK ++ F+ + ++A G+R + V PG T + L + A + T A
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRESIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 44.4 bits (100), Expect = 4e-04
Identities = 37/135 (27%), Positives = 65/135 (48%), Gaps = 6/135 (4%)
Query: 57 SITADLTKESDIEKI---IKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTN 112
++T D+TK + +K+ + G L LVNNAGI + T E + + +++ N
Sbjct: 79 TVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGISLPTAPNELLTKQDFVTILDVN 137
Query: 113 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 172
+ + +T+ +P + +++G G S G Y ISK V+ F+ + EL+
Sbjct: 138 LLGVIDVTLSLLPLVRKARGRVVNVSSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELSY 196
Query: 173 KGVRVNCVNPGVILT 187
GV+V + PG T
Sbjct: 197 FGVKVAMIEPGYFKT 211
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/162 (25%), Positives = 72/162 (44%), Gaps = 16/162 (9%)
Query: 78 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXX 134
H G +D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 9 HSG-VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHI 67
Query: 135 XXXXXXXGIRSFPGVLA--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ 190
G R P + Y+ +K +V T + EL A +R C++PGV+ T+
Sbjct: 68 ININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFA 127
Query: 191 -RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
+ E+ AA E+ K KP++VA + ++ S
Sbjct: 128 FKLHDKDPEKAAATYEQMKCL-------KPEDVAEAVIYVLS 162
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 82
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 141
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 82
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 141
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 82
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 141
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 82
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 141
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/162 (25%), Positives = 72/162 (44%), Gaps = 16/162 (9%)
Query: 78 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXX 134
H G +D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 9 HSG-VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHI 67
Query: 135 XXXXXXXGIRSFPGVLA--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ 190
G R P + Y+ +K +V T + EL A +R C++PGV+ T+
Sbjct: 68 ININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFA 127
Query: 191 -RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 231
+ E+ AA E+ K KP++VA + ++ S
Sbjct: 128 FKLHDKDPEKAAATYEQMKCL-------KPEDVAEAVIYVLS 162
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 82
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 141
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 82
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 83 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 141
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 142 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 189
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/136 (29%), Positives = 64/136 (47%), Gaps = 8/136 (5%)
Query: 57 SITADLTKESDIEKI---IKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRL--MNT 111
++T D+TK + +K+ + G L LVNNAGI T N L + D L ++
Sbjct: 79 TVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGI-SLPTAPNELLTKQDLLTILDV 136
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + +T+ +P + ++G G S G Y ISK V+ F+ + EL+
Sbjct: 137 NLLGVIDVTLNLLPLVRRARGRVVNVFSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELS 195
Query: 172 PKGVRVNCVNPGVILT 187
GV+V + PG T
Sbjct: 196 YFGVKVAMIEPGYFKT 211
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 42.7 bits (96), Expect = 0.001
Identities = 37/154 (24%), Positives = 66/154 (42%), Gaps = 12/154 (7%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYD----------RL 108
DL I + K I+ ++D+L+NNAG++ T E+ Q+ L
Sbjct: 26 DLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNL 85
Query: 109 MNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 168
+ +++ ++ + L G R + AY SK ++ FT+ ++
Sbjct: 86 LLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSR 145
Query: 169 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 202
L GV VN ++PGV TEL R G+ +++
Sbjct: 146 RLQGSGVTVNALHPGVARTELGRHTGIHGSTFSS 179
>BC064525-1|AAH64525.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase isoform 1 protein.
Length = 309
Score = 41.5 bits (93), Expect = 0.003
Identities = 38/192 (19%), Positives = 75/192 (39%), Gaps = 6/192 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 59
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 120 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL---APKGV 175
+P ++ G G+ G+ Y SK + F V +E KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 176 RVNCVNPGVILT 187
+ V P I T
Sbjct: 217 KTTIVCPFFIKT 228
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 41.5 bits (93), Expect = 0.003
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 111
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 172 PKGVRVNCVNPGVILTEL 189
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>BC037219-1|AAH37219.2| 309|Homo sapiens retinal short chain
dehydrogenase reductase isoform 1 protein.
Length = 309
Score = 41.5 bits (93), Expect = 0.003
Identities = 38/192 (19%), Positives = 75/192 (39%), Gaps = 6/192 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 59
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 120 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL---APKGV 175
+P ++ G G+ G+ Y SK + F V +E KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 176 RVNCVNPGVILT 187
+ V P I T
Sbjct: 217 KTTIVCPFFIKT 228
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 41.5 bits (93), Expect = 0.003
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 111
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 172 PKGVRVNCVNPGVILTEL 189
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid
dehydrogenase isoform 1 protein.
Length = 264
Score = 41.5 bits (93), Expect = 0.003
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 4/120 (3%)
Query: 72 IKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-S 130
I K G + ++VNNAG + + +T + + N+ +++T +P ++E +
Sbjct: 68 INKVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERN 127
Query: 131 KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE---LAPKGVRVNCVNPGVILT 187
G G P ++ Y SK + F R + E L G++ +C+ P + T
Sbjct: 128 HGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNT 187
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 41.5 bits (93), Expect = 0.003
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 111
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 172 PKGVRVNCVNPGVILTEL 189
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 41.5 bits (93), Expect = 0.003
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 111
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 172 PKGVRVNCVNPGVILTEL 189
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 41.5 bits (93), Expect = 0.003
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 111
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 172 PKGVRVNCVNPGVILTEL 189
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 41.5 bits (93), Expect = 0.003
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 111
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 172 PKGVRVNCVNPGVILTEL 189
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 41.5 bits (93), Expect = 0.003
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 111
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 172 PKGVRVNCVNPGVILTEL 189
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 41.5 bits (93), Expect = 0.003
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 111
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 172 PKGVRVNCVNPGVILTEL 189
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 41.5 bits (93), Expect = 0.003
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 57 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 111
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 112 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 171
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 172 PKGVRVNCVNPGVILTEL 189
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 41.5 bits (93), Expect = 0.003
Identities = 38/192 (19%), Positives = 75/192 (39%), Gaps = 6/192 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 59
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVRAYT 96
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 120 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL---APKGV 175
+P ++ G G+ G+ Y SK + F V +E KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 176 RVNCVNPGVILT 187
+ V P I T
Sbjct: 217 KTTIVCPFFIKT 228
>Z97054-9|CAI42652.1| 252|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase, type II protein.
Length = 252
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 13/129 (10%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 167 ALELAPKGV 175
A +LAP G+
Sbjct: 183 ARDLAPIGL 191
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 13/129 (10%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 166
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 167 ALELAPKGV 175
A +LAP G+
Sbjct: 183 ARDLAPIGL 191
>AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 147
Score = 41.1 bits (92), Expect = 0.004
Identities = 30/131 (22%), Positives = 54/131 (41%), Gaps = 2/131 (1%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
D+ ++ + K + G + +LVNNA ++ ++ ++ + + N ++ T
Sbjct: 11 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 70
Query: 121 MLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVN 178
+P +LE G + + PG + Y SKAS F + L L GV
Sbjct: 71 KAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSAT 130
Query: 179 CVNPGVILTEL 189
V P TE+
Sbjct: 131 TVLPFHTSTEM 141
>DQ338571-1|ABC61321.1| 160|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B2 isoform protein.
Length = 160
Score = 40.3 bits (90), Expect = 0.006
Identities = 20/43 (46%), Positives = 28/43 (65%)
Query: 205 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E KET + R G+P++ A ++FL S+ AS ITG +V V GG
Sbjct: 113 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 155
>AY943857-1|AAX49568.1| 57|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase A1 like protein 1 protein.
Length = 57
Score = 40.3 bits (90), Expect = 0.006
Identities = 20/43 (46%), Positives = 28/43 (65%)
Query: 205 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E KET + R G+P++ A ++FL S+ AS ITG +V V GG
Sbjct: 10 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 52
>AY616183-1|AAT70758.1| 91|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform-like protein 1
protein.
Length = 91
Score = 40.3 bits (90), Expect = 0.006
Identities = 20/43 (46%), Positives = 28/43 (65%)
Query: 205 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E KET + R G+P++ A ++FL S+ AS ITG +V V GG
Sbjct: 44 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 86
>AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol
dehydrogenase short isoform protein.
Length = 174
Score = 40.3 bits (90), Expect = 0.006
Identities = 20/43 (46%), Positives = 28/43 (65%)
Query: 205 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 247
E KET + R G+P++ A ++FL S+ AS ITG +V V GG
Sbjct: 127 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 169
Score = 31.9 bits (69), Expect = 2.2
Identities = 24/107 (22%), Positives = 48/107 (44%), Gaps = 2/107 (1%)
Query: 4 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 62
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 13 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 72
Query: 63 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRL 108
K D E+++ + +G +D+LV+NA + G+I + + +D+L
Sbjct: 73 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKL 119
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 40.3 bits (90), Expect = 0.006
Identities = 36/187 (19%), Positives = 73/187 (39%), Gaps = 6/187 (3%)
Query: 2 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 59
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 119
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 120 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL---APKGV 175
+P ++ G G+ G+ Y SK + F V +E KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 176 RVNCVNP 182
+ V P
Sbjct: 217 KTTIVCP 223
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 39.5 bits (88), Expect = 0.011
Identities = 49/203 (24%), Positives = 77/203 (37%), Gaps = 18/203 (8%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GKVV L++ GA++ L R+VE + V+K+ + D
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
L+ I K + L VL+NNAG++ + ++ + N + LT
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGHFLLTH 158
Query: 122 LAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFTRCVAL 168
L + L ES G + + LAY SK + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 169 ELAPKGVRVNCVNPGVILTELQR 191
L GV V+PG + +EL R
Sbjct: 219 RLKGSGVTTYSVHPGTVQSELVR 241
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 39.5 bits (88), Expect = 0.011
Identities = 49/203 (24%), Positives = 77/203 (37%), Gaps = 18/203 (8%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GKVV L++ GA++ L R+VE + V+K+ + D
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
L+ I K + L VL+NNAG++ + ++ + N + LT
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGHFLLTH 158
Query: 122 LAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFTRCVAL 168
L + L ES G + + LAY SK + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 169 ELAPKGVRVNCVNPGVILTELQR 191
L GV V+PG + +EL R
Sbjct: 219 RLKGSGVTTYSVHPGTVQSELVR 241
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 39.5 bits (88), Expect = 0.011
Identities = 49/203 (24%), Positives = 77/203 (37%), Gaps = 18/203 (8%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GKVV L++ GA++ L R+VE + V+K+ + D
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
L+ I K + L VL+NNAG++ + ++ + N + LT
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGHFLLTH 158
Query: 122 LAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFTRCVAL 168
L + L ES G + + LAY SK + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 169 ELAPKGVRVNCVNPGVILTELQR 191
L GV V+PG + +EL R
Sbjct: 219 RLKGSGVTTYSVHPGTVQSELVR 241
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 39.5 bits (88), Expect = 0.011
Identities = 49/203 (24%), Positives = 77/203 (37%), Gaps = 18/203 (8%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GKVV L++ GA++ L R+VE + V+K+ + D
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
L+ I K + L VL+NNAG++ + ++ + N + LT
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGHFLLTH 158
Query: 122 LAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFTRCVAL 168
L + L ES G + + LAY SK + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 169 ELAPKGVRVNCVNPGVILTELQR 191
L GV V+PG + +EL R
Sbjct: 219 RLKGSGVTTYSVHPGTVQSELVR 241
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 39.5 bits (88), Expect = 0.011
Identities = 49/203 (24%), Positives = 77/203 (37%), Gaps = 18/203 (8%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GKVV L++ GA++ L R+VE + V+K+ + D
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
L+ I K + L VL+NNAG++ + ++ + N + LT
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGHFLLTH 158
Query: 122 LAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFTRCVAL 168
L + L ES G + + LAY SK + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 169 ELAPKGVRVNCVNPGVILTELQR 191
L GV V+PG + +EL R
Sbjct: 219 RLKGSGVTTYSVHPGTVQSELVR 241
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 39.5 bits (88), Expect = 0.011
Identities = 49/203 (24%), Positives = 77/203 (37%), Gaps = 18/203 (8%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GKVV L++ GA++ L R+VE + V+K+ + D
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
L+ I K + L VL+NNAG++ + ++ + N + LT
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGHFLLTH 158
Query: 122 LAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFTRCVAL 168
L + L ES G + + LAY SK + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 169 ELAPKGVRVNCVNPGVILTELQR 191
L GV V+PG + +EL R
Sbjct: 219 RLKGSGVTTYSVHPGTVQSELVR 241
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 39.5 bits (88), Expect = 0.011
Identities = 49/203 (24%), Positives = 77/203 (37%), Gaps = 18/203 (8%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GKVV L++ GA++ L R+VE + V+K+ + D
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
L+ I K + L VL+NNAG++ + ++ + N + LT
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGHFLLTH 158
Query: 122 LAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFTRCVAL 168
L + L ES G + + LAY SK + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 169 ELAPKGVRVNCVNPGVILTELQR 191
L GV V+PG + +EL R
Sbjct: 219 RLKGSGVTTYSVHPGTVQSELVR 241
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 39.5 bits (88), Expect = 0.011
Identities = 49/203 (24%), Positives = 77/203 (37%), Gaps = 18/203 (8%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GKVV L++ GA++ L R+VE + V+K+ + D
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 121
L+ I K + L VL+NNAG++ + ++ + N + LT
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGHFLLTH 158
Query: 122 LAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFTRCVAL 168
L + L ES G + + LAY SK + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 169 ELAPKGVRVNCVNPGVILTELQR 191
L GV V+PG + +EL R
Sbjct: 219 RLKGSGVTTYSVHPGTVQSELVR 241
>AY268353-1|AAP42287.1| 199|Homo sapiens short-chain
dehydrogenase/reductase 10c protein.
Length = 199
Score = 37.9 bits (84), Expect = 0.034
Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 2/110 (1%)
Query: 69 EKIIKKTIDHYGKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL 127
E +++ +D G LD LV N+ G GT + A LM N S LT A+P L
Sbjct: 8 ESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSL 66
Query: 128 LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
+SKG G Y+ +K ++D F + EL + V V
Sbjct: 67 TDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 116
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 36.7 bits (81), Expect = 0.079
Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Query: 25 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 83
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 73 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 132
Query: 84 VLVNNAGIIE-TGTIENTSLAQYDRL 108
LV +AG+ G+ TS +D++
Sbjct: 133 FLVCSAGVNPLVGSTLGTSEQIWDKV 158
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 35.5 bits (78), Expect = 0.18
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 138
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 192
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 35.5 bits (78), Expect = 0.18
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 138
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 192
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 35.5 bits (78), Expect = 0.18
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 138
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 192
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 35.5 bits (78), Expect = 0.18
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 138
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 192
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 35.5 bits (78), Expect = 0.18
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 138
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 192
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 35.5 bits (78), Expect = 0.18
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 138
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 192
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 35.5 bits (78), Expect = 0.18
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Query: 80 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 138
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 192
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens
cDNA FLJ13960 fis, clone Y79AA1001233, weakly similar to
ESTRADIOL 17 BETA-DEHYDROGENASE 1 (EC 1.1.1.62). ).
Length = 219
Score = 34.7 bits (76), Expect = 0.32
Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 1/97 (1%)
Query: 95 GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYN 153
G +E SLA + +TN L +P + + G G++ Y
Sbjct: 5 GPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYA 64
Query: 154 ISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 190
SK +++ F +A++L + ++ V PG ++TE +
Sbjct: 65 ASKFALEGFFESLAIQLLQFNIFISLVEPGPVVTEFE 101
>BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 14
(all-trans/9-cis/11-cis) protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.73
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 15/144 (10%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 121 MLAVPHLLES-------------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 167
L + L S K +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 168 LELAPKGVRVNCVNPGVILTELQR 191
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.73
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 15/144 (10%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 121 MLAVPHLLES-------------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 167
L + L S K +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 168 LELAPKGVRVNCVNPGVILTELQR 191
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.73
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 15/144 (10%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 121 MLAVPHLLES-------------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 167
L + L S K +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 168 LELAPKGVRVNCVNPGVILTELQR 191
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.73
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 15/144 (10%)
Query: 61 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 120
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 121 MLAVPHLLES-------------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 167
L + L S K +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 168 LELAPKGVRVNCVNPGVILTELQR 191
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 33.1 bits (72), Expect = 0.97
Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 5 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 61
GKVV L++ GA++ L R+VE + V+K+ + D
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 62 LTKESDIEKIIKKTIDHYGKLDVLVNNAGII 92
L+ I K + L VL+NNAG++
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>AY123250-1|AAM64254.1| 986|Homo sapiens RTN4 isoform G protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123249-1|AAM64253.1| 986|Homo sapiens RTN4 isoform F protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123248-1|AAM64252.1| 986|Homo sapiens RTN4 isoform E protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123247-1|AAM64251.1| 986|Homo sapiens RTN4 isoform D protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123246-1|AAM64250.1| 986|Homo sapiens RTN4 isoform Ab protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123245-1|AAM64249.1| 986|Homo sapiens RTN4 isoform Aa protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY102285-4|AAM64244.1| 986|Homo sapiens RNT4 protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY102285-1|AAM64243.1| 1192|Homo sapiens RTN4 protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AY102279-1|AAM64248.1| 1192|Homo sapiens RTN4 isoform A protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AJ251383-1|CAB99248.1| 1192|Homo sapiens Nogo-A protein protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AF333336-1|AAK20831.1| 986|Homo sapiens testis specific
reticulon 5 protein protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AF148537-1|AAG12176.1| 1192|Homo sapiens reticulon 4a protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AC092461-1|AAX93116.1| 818|Homo sapiens unknown protein.
Length = 818
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 65 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 110
>AB073359-1|BAE45717.1| 294|Homo sapiens NOGO-A protein.
Length = 294
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 50 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 95
>AB040462-1|BAB18927.1| 1192|Homo sapiens RTN-xL protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AB020693-1|BAA74909.2| 1233|Homo sapiens KIAA0886 protein protein.
Length = 1233
Score = 32.3 bits (70), Expect = 1.7
Identities = 17/46 (36%), Positives = 25/46 (54%)
Query: 24 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 69
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 292 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 337
>BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein.
Length = 181
Score = 31.9 bits (69), Expect = 2.2
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 2/99 (2%)
Query: 80 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 138
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 1 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 59
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
G Y+ +K ++D F + EL + V V
Sbjct: 60 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 98
>BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein.
Length = 181
Score = 31.9 bits (69), Expect = 2.2
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 2/99 (2%)
Query: 80 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 138
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 1 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 59
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
G Y+ +K ++D F + EL + V V
Sbjct: 60 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 98
>AY313896-1|AAP83168.1| 234|Homo sapiens short-chain
dehydrogenase/reductase 10g protein.
Length = 234
Score = 31.9 bits (69), Expect = 2.2
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 2/99 (2%)
Query: 80 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 138
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 25 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 83
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
G Y+ +K ++D F + EL + V V
Sbjct: 84 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 122
>AY268351-1|AAP42285.1| 205|Homo sapiens short-chain
dehydrogenase/reductase 10a protein.
Length = 205
Score = 31.9 bits (69), Expect = 2.2
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 2/99 (2%)
Query: 80 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 138
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 25 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 83
Query: 139 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 177
G Y+ +K ++D F + EL + V V
Sbjct: 84 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 122
>Z97054-7|CAI42651.1| 169|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase, type II protein.
Length = 169
Score = 31.5 bits (68), Expect = 3.0
Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 60 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 113
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 114 RSIYYLTML 122
+ + L
Sbjct: 123 MGTFNVIRL 131
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 31.5 bits (68), Expect = 3.0
Identities = 19/45 (42%), Positives = 24/45 (53%)
Query: 151 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 195
AY SK + FTR +A L GV V+PGV+ +EL R L
Sbjct: 199 AYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSL 243
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.317 0.134 0.375
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 29,129,195
Number of Sequences: 224733
Number of extensions: 1034506
Number of successful extensions: 2499
Number of sequences better than 10.0: 259
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 2128
Number of HSP's gapped (non-prelim): 281
length of query: 254
length of database: 73,234,838
effective HSP length: 88
effective length of query: 166
effective length of database: 53,458,334
effective search space: 8874083444
effective search space used: 8874083444
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 64 (29.9 bits)
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