Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001313-TA|BGIBMGA001313-PA|IPR005829|Sugar transporter
superfamily, IPR007114|Major facilitator superfamily, IPR011701|Major
facilitator superfamily MFS_1
(549 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL591069-1|CAI16539.1| 556|Homo sapiens solute carrier family 2... 189 2e-47
AL355506-1|CAI20340.1| 556|Homo sapiens solute carrier family 2... 189 2e-47
AJ001417-1|CAA04751.1| 556|Homo sapiens extraneuronal monoamine... 189 2e-47
AJ403946-1|CAC39443.1| 557|Homo sapiens organic cation transpor... 185 4e-46
Y09881-1|CAA71007.1| 551|Homo sapiens ergothioneine transporter... 178 4e-44
X98333-1|CAA66978.1| 555|Homo sapiens organic cation transporte... 178 4e-44
BC039899-1|AAH39899.1| 555|Homo sapiens solute carrier family 2... 178 4e-44
BC028313-1|AAH28313.1| 551|Homo sapiens solute carrier family 2... 178 4e-44
AL162582-1|CAI20003.1| 555|Homo sapiens solute carrier family 2... 178 4e-44
AB007448-1|BAA23356.1| 551|Homo sapiens OCTN1 protein. 177 8e-44
U77086-1|AAB67703.1| 554|Homo sapiens organic cation transporte... 173 1e-42
BC012325-1|AAH12325.1| 557|Homo sapiens solute carrier family 2... 173 1e-42
AL353625-3|CAH72016.1| 554|Homo sapiens solute carrier family 2... 173 1e-42
AF057164-1|AAC24828.1| 557|Homo sapiens organic cation transpor... 173 1e-42
AB016625-1|BAA36712.1| 557|Homo sapiens OCTN2 protein. 173 1e-42
AB015050-1|BAA29023.1| 557|Homo sapiens OCTN2 protein. 173 1e-42
X98332-1|CAA66977.1| 554|Homo sapiens organic cation transporte... 171 4e-42
BC126364-1|AAI26365.1| 554|Homo sapiens solute carrier family 2... 171 4e-42
AJ243995-1|CAB95971.1| 554|Homo sapiens protein ( Homo sapiens ... 169 2e-41
BC022387-1|AAH22387.1| 542|Homo sapiens solute carrier family 2... 161 8e-39
AB042505-1|BAB47393.1| 542|Homo sapiens organic anion transport... 161 8e-39
AB291606-1|BAF45812.1| 581|Homo sapiens organic cation transpor... 157 1e-37
BC047565-1|AAH47565.1| 577|Homo sapiens solute carrier family 2... 156 2e-37
AL050350-4|CAI42512.1| 577|Homo sapiens solute carrier family 2... 156 2e-37
BC033682-1|AAH33682.1| 550|Homo sapiens solute carrier family 2... 155 5e-37
AJ249369-1|CAB77184.1| 563|Homo sapiens organic anion transport... 155 5e-37
AF268892-1|AAK58593.1| 577|Homo sapiens organic cation transpor... 155 5e-37
AF124373-1|AAD55356.1| 550|Homo sapiens organic anion transport... 155 5e-37
AF097490-1|AAD19356.1| 550|Homo sapiens organic anion transport... 155 5e-37
AF057039-1|AAC70004.1| 550|Homo sapiens putative renal organic ... 155 5e-37
AB055798-1|BAC23062.1| 543|Homo sapiens carnitine transporter 2... 155 5e-37
AB009698-1|BAA75073.1| 550|Homo sapiens hOAT1-2 protein. 155 5e-37
AB009697-1|BAA75072.1| 563|Homo sapiens hOAT1-1 protein. 155 5e-37
AY145502-1|AAN52928.1| 577|Homo sapiens putative transmembrane ... 154 9e-37
BC026358-1|AAH26358.1| 535|Homo sapiens solute carrier family 2... 153 1e-36
AY145501-1|AAN52927.1| 547|Homo sapiens putative transmembrane ... 153 2e-36
AL365318-2|CAH70686.1| 547|Homo sapiens solute carrier family 2... 153 2e-36
AL357137-2|CAH70380.1| 547|Homo sapiens solute carrier family 2... 153 2e-36
AF104038-1|AAD10052.1| 550|Homo sapiens para-aminohippurate tra... 153 2e-36
BC053348-1|AAH53348.1| 553|Homo sapiens solute carrier family 2... 150 1e-35
AC044790-2|AAK68156.1| 553|Homo sapiens RST protein. 150 1e-35
AB071863-1|BAB96750.1| 553|Homo sapiens URAT1 protein. 150 1e-35
AL050350-6|CAI42514.1| 432|Homo sapiens solute carrier family 2... 149 2e-35
AB026898-2|BAA77625.1| 551|Homo sapiens organic-cation transpor... 146 2e-34
AB010438-1|BAA76350.1| 551|Homo sapiens organic-cation transpor... 146 2e-34
AJ271205-1|CAB97249.1| 519|Homo sapiens putative organic anion ... 137 1e-31
AJ251529-1|CAB94830.1| 506|Homo sapiens putative organic anion ... 137 1e-31
AC002464-1|AAB67044.1| 456|Homo sapiens WUGSC:RG331P03.1 protein. 135 4e-31
AB050269-1|BAB68364.1| 552|Homo sapiens organic anion transpote... 133 1e-30
AB209484-1|BAD92721.1| 440|Homo sapiens solute carrier family 2... 132 2e-30
AK057306-1|BAB71419.1| 361|Homo sapiens protein ( Homo sapiens ... 129 2e-29
AB075951-1|BAC02720.1| 483|Homo sapiens organic cation transpor... 126 2e-28
AL583834-3|CAI14462.1| 539|Homo sapiens solute carrier family 2... 125 5e-28
AF097491-1|AAD19357.1| 568|Homo sapiens organic anion transport... 125 5e-28
AF210455-1|AAG43523.1| 539|Homo sapiens organic anion transport... 124 1e-27
AL583834-4|CAI14464.1| 546|Homo sapiens solute carrier family 2... 123 2e-27
BC035973-1|AAH35973.1| 468|Homo sapiens SLC22A13 protein protein. 121 6e-27
BC033805-1|AAH33805.1| 548|Homo sapiens solute carrier family 2... 121 6e-27
AY050498-1|AAL12496.1| 548|Homo sapiens organic anion transport... 121 6e-27
AL583834-5|CAI14463.1| 548|Homo sapiens solute carrier family 2... 121 6e-27
AF097518-1|AAD37091.1| 548|Homo sapiens liver-specific transpor... 121 6e-27
BC034384-1|AAH34384.1| 550|Homo sapiens solute carrier family 2... 118 7e-26
AC044790-3|AAK68155.1| 550|Homo sapiens OAT4 protein. 118 7e-26
AB026116-1|BAA95316.1| 550|Homo sapiens organic anion transport... 118 7e-26
AK222869-1|BAD96589.1| 550|Homo sapiens solute carrier family 2... 116 2e-25
AY437532-1|AAR84082.1| 547|Homo sapiens putative UST1-like orga... 109 2e-23
BC101316-1|AAI01317.1| 547|Homo sapiens LOC387601 protein protein. 109 2e-23
AK075224-1|BAC11483.1| 401|Homo sapiens protein ( Homo sapiens ... 102 3e-21
AL162582-2|CAI20004.1| 334|Homo sapiens solute carrier family 2... 102 4e-21
BC126288-1|AAI26289.1| 553|Homo sapiens solute carrier family 2... 100 1e-20
AJ295270-1|CAC82910.1| 553|Homo sapiens putative integral membr... 100 1e-20
AF440402-1|AAP97316.1| 553|Homo sapiens putative integral membr... 100 1e-20
AB074812-1|BAF51552.1| 553|Homo sapiens organic anion transport... 100 1e-20
AB062418-1|BAB83517.1| 553|Homo sapiens hUST3 protein. 100 1e-20
AK074246-1|BAB85030.1| 552|Homo sapiens protein ( Homo sapiens ... 100 3e-20
AK129930-1|BAC85252.1| 442|Homo sapiens er 11 (SLC22A11). prot... 87 2e-16
AY358183-1|AAQ88550.1| 445|Homo sapiens SLC22A12 protein. 83 2e-15
BC126482-1|AAI26483.1| 594|Homo sapiens solute carrier family 2... 82 6e-15
BC130543-1|AAI30544.1| 594|Homo sapiens solute carrier family 2... 81 7e-15
BC075071-1|AAH75071.1| 594|Homo sapiens solute carrier family 2... 81 7e-15
BC075070-1|AAH75070.1| 594|Homo sapiens solute carrier family 2... 81 7e-15
AK128610-1|BAC87527.1| 221|Homo sapiens . protein. 80 2e-14
AB026898-3|BAA77626.1| 594|Homo sapiens organic-cation transpor... 78 7e-14
AB011082-1|BAA76351.1| 594|Homo sapiens organic-cation transpor... 78 7e-14
BC101315-1|AAI01316.1| 398|Homo sapiens LOC387601 protein protein. 72 6e-12
AB075876-1|BAD38658.1| 269|Homo sapiens putative protein produc... 69 3e-11
BC034394-1|AAH34394.1| 322|Homo sapiens hypothetical protein MG... 69 6e-11
BC030978-1|AAH30978.1| 242|Homo sapiens SLC22A2 protein protein. 67 1e-10
BC026291-1|AAH26291.1| 440|Homo sapiens Unknown (protein for IM... 67 2e-10
CR457086-1|CAG33367.1| 683|Homo sapiens SV2B protein. 66 2e-10
BC030011-1|AAH30011.1| 683|Homo sapiens SV2B protein protein. 66 2e-10
AB018278-1|BAA34455.2| 707|Homo sapiens KIAA0735 protein protein. 66 2e-10
BC090870-1|AAH90870.1| 449|Homo sapiens SLC22A17 protein protein. 65 7e-10
AK127610-1|BAC87056.1| 248|Homo sapiens protein ( Homo sapiens ... 62 5e-09
BC040876-1|AAH40876.1| 341|Homo sapiens C6orf85 protein protein. 62 6e-09
AL583834-7|CAI14466.1| 211|Homo sapiens solute carrier family 2... 62 6e-09
AL445309-6|CAI40959.1| 213|Homo sapiens chromosome 6 open readi... 62 6e-09
AL160398-1|CAI12303.1| 213|Homo sapiens chromosome 6 open readi... 62 6e-09
BC020565-1|AAH20565.1| 538|Homo sapiens solute carrier family 2... 60 1e-08
BC111015-1|AAI11016.1| 403|Homo sapiens SLC22A17 protein protein. 60 3e-08
BC094722-1|AAH94722.1| 548|Homo sapiens SV2 related protein hom... 58 6e-08
BC033587-1|AAH33587.1| 548|Homo sapiens SV2 related protein hom... 58 6e-08
BX537754-1|CAD97824.1| 742|Homo sapiens hypothetical protein pr... 58 8e-08
BC045111-1|AAH45111.1| 742|Homo sapiens synaptic vesicle glycop... 58 8e-08
BC000776-1|AAH00776.2| 604|Homo sapiens SV2A protein protein. 58 8e-08
AL591493-21|CAI12573.1| 682|Homo sapiens synaptic vesicle glyco... 58 8e-08
AL591493-20|CAI12572.1| 742|Homo sapiens synaptic vesicle glyco... 58 8e-08
AK075480-1|BAC11645.1| 682|Homo sapiens protein ( Homo sapiens ... 58 8e-08
AB018279-1|BAA34456.2| 748|Homo sapiens KIAA0736 protein protein. 58 8e-08
AY358258-1|AAQ88625.1| 245|Homo sapiens trans-like protein prot... 58 1e-07
AL365318-1|CAH70685.1| 245|Homo sapiens solute carrier family 2... 58 1e-07
AL357137-1|CAH70379.1| 245|Homo sapiens solute carrier family 2... 58 1e-07
AK131327-1|BAD18487.1| 349|Homo sapiens protein ( Homo sapiens ... 56 3e-07
BC070149-1|AAH70149.1| 617|Homo sapiens solute carrier family 2... 56 4e-07
AY046419-1|AAL02327.1| 617|Homo sapiens glucose transporter pro... 56 4e-07
AL449363-1|CAI17977.1| 617|Homo sapiens solute carrier family 2... 56 4e-07
AL035699-6|CAD92514.2| 617|Homo sapiens solute carrier family 2... 56 4e-07
BC100827-1|AAI00828.1| 727|Homo sapiens synaptic vesicle glycop... 55 7e-07
BC100826-1|AAI00827.1| 727|Homo sapiens synaptic vesicle glycop... 55 7e-07
BC100825-1|AAI00826.1| 727|Homo sapiens synaptic vesicle glycop... 55 7e-07
BC100824-1|AAI00825.1| 727|Homo sapiens synaptic vesicle glycop... 53 2e-06
AL583834-6|CAI14465.1| 147|Homo sapiens solute carrier family 2... 52 4e-06
AL583834-2|CAI14461.1| 278|Homo sapiens solute carrier family 2... 48 1e-04
AY517500-1|AAS76641.1| 234|Homo sapiens putative integral membr... 47 2e-04
AK091990-1|BAC03786.1| 234|Homo sapiens protein ( Homo sapiens ... 47 2e-04
BC121804-1|AAI21805.1| 492|Homo sapiens solute carrier family 2... 46 5e-04
BC118590-1|AAI18591.1| 492|Homo sapiens solute carrier family 2... 46 5e-04
AB208987-1|BAD92224.1| 517|Homo sapiens solute carrier family 2... 46 5e-04
K03195-1|AAA52571.1| 492|Homo sapiens SGLT1 protein. 45 6e-04
BC128580-1|AAI28581.1| 405|Homo sapiens C6orf85 protein protein. 45 6e-04
BC036796-1|AAH36796.1| 340|Homo sapiens SVOP-like protein. 44 0.002
M91463-1|AAA52569.1| 505|Homo sapiens glucose transporter protein. 43 0.002
AK075127-1|BAC11419.1| 248|Homo sapiens protein ( Homo sapiens ... 42 0.006
AB028977-1|BAA83006.1| 480|Homo sapiens KIAA1054 protein protein. 41 0.010
AL445309-7|CAI40960.1| 175|Homo sapiens chromosome 6 open readi... 40 0.023
AL160398-2|CAI12304.1| 175|Homo sapiens chromosome 6 open readi... 40 0.023
AL110245-1|CAB53695.1| 175|Homo sapiens hypothetical protein pr... 40 0.023
M20747-1|AAA59189.1| 509|Homo sapiens GLUT4 protein. 40 0.030
BC126164-1|AAI26165.1| 509|Homo sapiens solute carrier family 2... 40 0.030
BC113592-1|AAI13593.1| 509|Homo sapiens solute carrier family 2... 40 0.030
BC069621-1|AAH69621.1| 509|Homo sapiens solute carrier family 2... 40 0.030
BC069615-1|AAH69615.1| 509|Homo sapiens solute carrier family 2... 40 0.030
BC034387-1|AAH34387.1| 415|Homo sapiens SLC2A4 protein protein. 40 0.030
AJ243653-1|CAC01119.1| 366|Homo sapiens organic cation transpor... 40 0.030
AJ243122-1|CAC17762.1| 366|Homo sapiens organic cation transpor... 39 0.040
Y17801-1|CAB89809.1| 477|Homo sapiens glucose transporter 8 pro... 38 0.091
BC019043-1|AAH19043.1| 477|Homo sapiens solute carrier family 2... 38 0.091
BC012014-1|AAH12014.1| 177|Homo sapiens SLC22A16 protein protein. 38 0.091
AL445309-8|CAI40961.1| 381|Homo sapiens chromosome 6 open readi... 38 0.091
AL445222-5|CAH72918.1| 477|Homo sapiens solute carrier family 2... 38 0.091
AL445222-4|CAH72917.1| 411|Homo sapiens solute carrier family 2... 38 0.091
AJ245937-1|CAB75702.1| 477|Homo sapiens glucose transporter pro... 38 0.091
BC113423-1|AAI13424.1| 541|Homo sapiens solute carrier family 2... 37 0.21
BC101657-1|AAI01658.1| 541|Homo sapiens solute carrier family 2... 37 0.21
AL137188-1|CAB69822.2| 541|Homo sapiens hypothetical protein pr... 37 0.21
AL031055-3|CAA19926.2| 541|Homo sapiens solute carrier family 2... 37 0.21
AF321240-1|AAK26294.1| 541|Homo sapiens facilitative glucose tr... 37 0.21
AF248053-1|AAK31911.1| 541|Homo sapiens glucose transporter pro... 37 0.21
BC110414-1|AAI10415.1| 540|Homo sapiens solute carrier family 2... 36 0.49
BC018897-1|AAH18897.1| 511|Homo sapiens solute carrier family 2... 36 0.49
AF210317-1|AAF85942.1| 540|Homo sapiens facilitative glucose tr... 36 0.49
BC036662-1|AAH36662.1| 461|Homo sapiens solute carrier family 4... 35 0.64
BX537565-1|CAD97783.1| 461|Homo sapiens hypothetical protein pr... 35 0.85
BC060850-1|AAH60850.1| 463|Homo sapiens SLC46A3 protein protein. 35 0.85
AL359454-3|CAM24029.1| 461|Homo sapiens novel protein protein. 35 0.85
AL359454-2|CAI17158.1| 463|Homo sapiens novel protein protein. 35 0.85
AK124604-1|BAC85896.1| 304|Homo sapiens protein ( Homo sapiens ... 35 0.85
BC068556-1|AAH68556.1| 461|Homo sapiens solute carrier family 4... 34 1.1
BC041772-1|AAH41772.2| 549|Homo sapiens LOC124976 protein protein. 33 2.0
AJ315644-1|CAC51116.1| 629|Homo sapiens proton myo-inositol tra... 33 2.0
U79745-1|AAC52014.1| 523|Homo sapiens monocarboxylate transport... 33 2.6
BC117119-1|AAI17120.1| 629|Homo sapiens solute carrier family 2... 33 2.6
BC117117-1|AAI17118.1| 629|Homo sapiens solute carrier family 2... 33 2.6
BC064832-1|AAH64832.1| 523|Homo sapiens solute carrier family 1... 33 2.6
BC047507-1|AAH47507.1| 338|Homo sapiens SLC2A13 protein protein. 33 2.6
BC015571-1|AAH15571.1| 424|Homo sapiens solute carrier family 2... 33 3.4
AF421859-1|AAL16939.1| 199|Homo sapiens solute carrier family 2... 33 3.4
AF070479-1|AAC23505.1| 424|Homo sapiens efflux transporter like... 33 3.4
AF059663-1|AAC14725.1| 424|Homo sapiens tumor suppressing STF c... 33 3.4
AF037064-1|AAC04787.1| 424|Homo sapiens organic cation transpor... 33 3.4
AF028738-1|AAB82727.1| 408|Homo sapiens imprinted multi-membran... 33 3.4
AB012083-1|BAA32779.1| 408|Homo sapiens ITM protein. 33 3.4
DQ658848-1|ABG45942.1| 207|Homo sapiens esophageal carcinoma NG... 32 4.5
AY571960-1|AAS78590.2| 512|Homo sapiens intestinal facilitative... 32 4.5
AL158048-4|CAI23459.2| 524|Homo sapiens solute carrier family 2... 32 4.5
U11843-1|AAB60641.1| 481|Homo sapiens fructose transporter prot... 32 6.0
M55531-1|AAA52570.1| 501|Homo sapiens GLUT5 protein protein. 32 6.0
BC001820-1|AAH01820.1| 501|Homo sapiens solute carrier family 2... 32 6.0
BC001692-1|AAH01692.1| 501|Homo sapiens solute carrier family 2... 32 6.0
AL158048-3|CAI23458.1| 501|Homo sapiens solute carrier family 2... 32 6.0
BC131825-1|AAI31826.1| 479|Homo sapiens FLJ45557 protein protein. 31 7.9
BC057236-1|AAH57236.1| 270|Homo sapiens ATP8B4 protein protein. 31 7.9
AK127465-1|BAC86991.1| 479|Homo sapiens protein ( Homo sapiens ... 31 7.9
AK025125-1|BAB15072.1| 195|Homo sapiens roto-LBC) mRNA. protein. 31 7.9
AB075819-1|BAB85525.1| 1082|Homo sapiens KIAA1939 protein protein. 31 7.9
>AL591069-1|CAI16539.1| 556|Homo sapiens solute carrier family 22
(extraneuronal monoamined) (PLP2) pseudogene protein.
Length = 556
Score = 189 bits (461), Expect = 2e-47
Identities = 118/438 (26%), Positives = 201/438 (45%), Gaps = 16/438 (3%)
Query: 103 PCSADTSFSQEALAC-DHWIYAN-NNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPIL 159
P +A + S + C W YA ++TIV+EF+L C W L I N+G L L
Sbjct: 113 PLAAFPNRSAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTL 172
Query: 160 GYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIE 219
GY +DR+GR V +LSC VGV G + AF+ ++ ++VI FL+ + G T+ Y++ E
Sbjct: 173 GYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTE 232
Query: 220 LLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESI 279
++G +R + + + ++G + +A W+ L + P+ LFL Y + +PES
Sbjct: 233 IVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESP 292
Query: 280 RWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVM 339
RWL++ N D +E+ N + ++
Sbjct: 293 RWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTD--------EEVSNPS--FLDLV 342
Query: 340 RSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLD 399
R+P + K I + W T V+ GL + + G+ Y ++ + + L ++
Sbjct: 343 RTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIE 402
Query: 400 RIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFP 459
R+GR+ +V GV+C F+ I WL + LG++ IT AF +Y+ SEL+P
Sbjct: 403 RLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYP 462
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKW--LPSVLFGCTALVAGXXXXXXXXXX 517
T R+ ++ CS + G I+AP + L + W LP ++FG A + G
Sbjct: 463 TTLRNFGVSLCSGLCDFGGIIAPFL-LFRLAAVWLELPLIIFGILASICGGLVMLLPETK 521
Query: 518 XXXXXXXIQEAEQIATRH 535
+ + E++ + H
Sbjct: 522 GIALPETVDDVEKLGSPH 539
>AL355506-1|CAI20340.1| 556|Homo sapiens solute carrier family 22
(extraneuronal monoaminen 1 protein.
Length = 556
Score = 189 bits (461), Expect = 2e-47
Identities = 118/438 (26%), Positives = 201/438 (45%), Gaps = 16/438 (3%)
Query: 103 PCSADTSFSQEALAC-DHWIYAN-NNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPIL 159
P +A + S + C W YA ++TIV+EF+L C W L I N+G L L
Sbjct: 113 PLAAFPNRSAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTL 172
Query: 160 GYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIE 219
GY +DR+GR V +LSC VGV G + AF+ ++ ++VI FL+ + G T+ Y++ E
Sbjct: 173 GYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTE 232
Query: 220 LLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESI 279
++G +R + + + ++G + +A W+ L + P+ LFL Y + +PES
Sbjct: 233 IVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESP 292
Query: 280 RWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVM 339
RWL++ N D +E+ N + ++
Sbjct: 293 RWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTD--------EEVSNPS--FLDLV 342
Query: 340 RSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLD 399
R+P + K I + W T V+ GL + + G+ Y ++ + + L ++
Sbjct: 343 RTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIE 402
Query: 400 RIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFP 459
R+GR+ +V GV+C F+ I WL + LG++ IT AF +Y+ SEL+P
Sbjct: 403 RLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYP 462
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKW--LPSVLFGCTALVAGXXXXXXXXXX 517
T R+ ++ CS + G I+AP + L + W LP ++FG A + G
Sbjct: 463 TTLRNFGVSLCSGLCDFGGIIAPFL-LFRLAAVWLELPLIIFGILASICGGLVMLLPETK 521
Query: 518 XXXXXXXIQEAEQIATRH 535
+ + E++ + H
Sbjct: 522 GIALPETVDDVEKLGSPH 539
>AJ001417-1|CAA04751.1| 556|Homo sapiens extraneuronal monoamine
transporter protein.
Length = 556
Score = 189 bits (461), Expect = 2e-47
Identities = 118/438 (26%), Positives = 201/438 (45%), Gaps = 16/438 (3%)
Query: 103 PCSADTSFSQEALAC-DHWIYAN-NNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPIL 159
P +A + S + C W YA ++TIV+EF+L C W L I N+G L L
Sbjct: 113 PLAAFPNRSAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTL 172
Query: 160 GYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIE 219
GY +DR+GR V +LSC VGV G + AF+ ++ ++VI FL+ + G T+ Y++ E
Sbjct: 173 GYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTE 232
Query: 220 LLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESI 279
++G +R + + + ++G + +A W+ L + P+ LFL Y + +PES
Sbjct: 233 IVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESP 292
Query: 280 RWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVM 339
RWL++ N D +E+ N + ++
Sbjct: 293 RWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTD--------EEVSNPS--FLDLV 342
Query: 340 RSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLD 399
R+P + K I + W T V+ GL + + G+ Y ++ + + L ++
Sbjct: 343 RTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIE 402
Query: 400 RIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFP 459
R+GR+ +V GV+C F+ I WL + LG++ IT AF +Y+ SEL+P
Sbjct: 403 RLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYP 462
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKW--LPSVLFGCTALVAGXXXXXXXXXX 517
T R+ ++ CS + G I+AP + L + W LP ++FG A + G
Sbjct: 463 TTLRNFGVSLCSGLCDFGGIIAPFL-LFRLAAVWLELPLIIFGILASICGGLVMLLPETK 521
Query: 518 XXXXXXXIQEAEQIATRH 535
+ + E++ + H
Sbjct: 522 GIALPETVDDVEKLGSPH 539
>AJ403946-1|CAC39443.1| 557|Homo sapiens organic cation transporter
3 protein.
Length = 557
Score = 185 bits (450), Expect = 4e-46
Identities = 118/439 (26%), Positives = 201/439 (45%), Gaps = 17/439 (3%)
Query: 103 PCSADTSFSQEALAC-DHWIYAN-NNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPIL 159
P +A + S + C W YA ++TIV+EF+L C W L I N+G L L
Sbjct: 113 PLAAFPNRSAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTL 172
Query: 160 GYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIE 219
GY +DR+GR V +LSC VGV G + AF+ ++ ++VI FL+ + G T+ Y++ E
Sbjct: 173 GYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTE 232
Query: 220 LLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESI 279
++G +R + + + ++G + +A W+ L + P+ LFL Y + +PES
Sbjct: 233 IVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESP 292
Query: 280 RWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVM 339
RWL++ N D +E+ N + ++
Sbjct: 293 RWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTD--------EEVSNPS--FLDLV 342
Query: 340 RSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLD 399
R+P + K I + W T V+ GL + + G+ Y ++ + + L ++
Sbjct: 343 RTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIE 402
Query: 400 RIGRKRSLLIGFMVCGVSCCAIPFV-RNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
R+GR+ +V GV+C F+ I WL + LG++ IT AF +Y+ SEL+
Sbjct: 403 RLGRRLPFAASNIVAGVACLVTAFLPEAGIAWLRTTVATLGRLGITMAFEIVYLVNSELY 462
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKW--LPSVLFGCTALVAGXXXXXXXXX 516
PT R+ ++ CS + G I+AP + L + W LP ++FG A + G
Sbjct: 463 PTTLRNFGVSLCSGLCDFGGIIAPFL-LFRLAAVWLELPLIIFGILASICGGLVMLLPET 521
Query: 517 XXXXXXXXIQEAEQIATRH 535
+ + E++ + H
Sbjct: 522 KGIALPETVDDVEKLGSPH 540
>Y09881-1|CAA71007.1| 551|Homo sapiens ergothioneine transporter
(ETT) protein.
Length = 551
Score = 178 bits (434), Expect = 4e-44
Identities = 135/509 (26%), Positives = 234/509 (45%), Gaps = 28/509 (5%)
Query: 17 DVDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTD 76
D D V+ LG+ G F G + +FLAG+ +RC VP+ +L++
Sbjct: 3 DYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSSAW 62
Query: 77 FNPVWLPNAAVEGQG--ERCSR-RVPLTQPCSA-------DTSFSQ-EALAC-DHWIYAN 124
N +P +G+ CSR R+ SA D Q E +C D W ++
Sbjct: 63 RNNS-VPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQ 121
Query: 125 N---NTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVG 180
+ +T+V E+NL C++ WK L ++ +G+L+ + G +SDRFGRK L + +
Sbjct: 122 DVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQT 181
Query: 181 VIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIV--IS 238
L+ FS+S+EM+ ++ + + S + ++IL E+LG+ R++ + LG+ +
Sbjct: 182 GFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFST-LGVCTFFA 240
Query: 239 MGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXX 298
+G + L A + WR +L + P +L + +F+PES RWL+S
Sbjct: 241 VGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKA 300
Query: 299 XXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITC 358
MNN+ ++EE ++ + + R+ I + W+
Sbjct: 301 AKMNNIAVPAVIF--------DSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLT 352
Query: 359 TFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSC 418
+ ++ L++++ +L GD Y N L L+L + R+ + G
Sbjct: 353 SVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVL 412
Query: 419 CAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGS 478
I V +LSI L +LGK IT AF+ +Y++T+EL+PT R+ + S R+GS
Sbjct: 413 LFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGS 472
Query: 479 IVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
I+AP L Y + LP ++ G ++ G
Sbjct: 473 IIAPYFVYLGAYNRMLPYIVMGSLTVLIG 501
>X98333-1|CAA66978.1| 555|Homo sapiens organic cation transporter
protein.
Length = 555
Score = 178 bits (434), Expect = 4e-44
Identities = 128/446 (28%), Positives = 203/446 (45%), Gaps = 21/446 (4%)
Query: 105 SADTSFSQEALA-C-DHWIYAN-NNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILG 160
S DT+ S+ L C D W+Y ++IV EFNL C W L + N+G + +G
Sbjct: 109 SLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIG 168
Query: 161 YISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIEL 220
YI+DRFGRK+ L+ + + G L A S +Y +I ++ + + + YIL E
Sbjct: 169 YIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEF 228
Query: 221 LGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIR 280
+G+ R F + ++G + A +A +WR V P FL Y + +PES R
Sbjct: 229 VGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPESPR 288
Query: 281 WLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMR 340
WL+S N + +EE+ + P + ++R
Sbjct: 289 WLISQNKNAEAMRIIKHIAKKNGKSLPASL-------QRLRLEEETGKKLNPS-FLDLVR 340
Query: 341 SPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDK-YTNYMLXXXXXXXXXXINALVLD 399
+P I K I + W T + ++ GL I + LAGD Y ++ + L +D
Sbjct: 341 TPQIRKHTMILMYNWFTSSVLYQGL-IMHMGLAGDNIYLDFFYSALVEFPAAFMIILTID 399
Query: 400 RIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFP 459
RIGR+ MV G +C A F+ + WL I + LG++ IT A+ + + +EL+P
Sbjct: 400 RIGRRYPWAASNMVAGAACLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYP 459
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQM--PLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXX 517
T R+ + CS + IG I+ P + L I+++ LP ++FG LVAG
Sbjct: 460 TFIRNLGVHICSSMCDIGGIITPFLVYRLTNIWLE-LPLMVFGVLGLVAGGLVLLLPETK 518
Query: 518 XXXXXXXIQEAEQIATRHREPHKSKE 543
I+EAE + + P K+KE
Sbjct: 519 GKALPETIEEAENM----QRPRKNKE 540
>BC039899-1|AAH39899.1| 555|Homo sapiens solute carrier family 22
(organic cation transporter), member 2 protein.
Length = 555
Score = 178 bits (434), Expect = 4e-44
Identities = 128/446 (28%), Positives = 203/446 (45%), Gaps = 21/446 (4%)
Query: 105 SADTSFSQEALA-C-DHWIYAN-NNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILG 160
S DT+ S+ L C D W+Y ++IV EFNL C W L + N+G + +G
Sbjct: 109 SLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIG 168
Query: 161 YISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIEL 220
YI+DRFGRK+ L+ + + G L A S +Y +I ++ + + + YIL E
Sbjct: 169 YIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEF 228
Query: 221 LGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIR 280
+G+ R F + ++G + A +A +WR V P FL Y + +PES R
Sbjct: 229 VGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPESPR 288
Query: 281 WLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMR 340
WL+S N + +EE+ + P + ++R
Sbjct: 289 WLISQNKNAEAMRIIKHIAKKNGKSLPASL-------QRLRLEEETGKKLNPS-FLDLVR 340
Query: 341 SPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDK-YTNYMLXXXXXXXXXXINALVLD 399
+P I K I + W T + ++ GL I + LAGD Y ++ + L +D
Sbjct: 341 TPQIRKHTMILMYNWFTSSVLYQGL-IMHMGLAGDNIYLDFFYSALVEFPAAFMIILTID 399
Query: 400 RIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFP 459
RIGR+ MV G +C A F+ + WL I + LG++ IT A+ + + +EL+P
Sbjct: 400 RIGRRYPWAASNMVAGAACLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYP 459
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQM--PLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXX 517
T R+ + CS + IG I+ P + L I+++ LP ++FG LVAG
Sbjct: 460 TFIRNLGVHICSSMCDIGGIITPFLVYRLTNIWLE-LPLMVFGVLGLVAGGLVLLLPETK 518
Query: 518 XXXXXXXIQEAEQIATRHREPHKSKE 543
I+EAE + + P K+KE
Sbjct: 519 GKALPETIEEAENM----QRPRKNKE 540
>BC028313-1|AAH28313.1| 551|Homo sapiens solute carrier family 22
(organic cation transporter), member 4 protein.
Length = 551
Score = 178 bits (434), Expect = 4e-44
Identities = 135/509 (26%), Positives = 234/509 (45%), Gaps = 28/509 (5%)
Query: 17 DVDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTD 76
D D V+ LG+ G F G + +FLAG+ +RC VP+ +L++
Sbjct: 3 DYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSSAW 62
Query: 77 FNPVWLPNAAVEGQG--ERCSR-RVPLTQPCSA-------DTSFSQ-EALAC-DHWIYAN 124
N +P +G+ CSR R+ SA D Q E +C D W ++
Sbjct: 63 RNNS-VPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQ 121
Query: 125 N---NTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVG 180
+ +T+V E+NL C++ WK L ++ +G+L+ + G +SDRFGRK L + +
Sbjct: 122 DVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQT 181
Query: 181 VIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIV--IS 238
L+ FS+S+EM+ ++ + + S + ++IL E+LG+ R++ + LG+ +
Sbjct: 182 GFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFST-LGVCTFFA 240
Query: 239 MGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXX 298
+G + L A + WR +L + P +L + +F+PES RWL+S
Sbjct: 241 VGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKA 300
Query: 299 XXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITC 358
MNN+ ++EE ++ + + R+ I + W+
Sbjct: 301 AKMNNIAVPAVIF--------DSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLT 352
Query: 359 TFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSC 418
+ ++ L++++ +L GD Y N L L+L + R+ + G
Sbjct: 353 SVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVL 412
Query: 419 CAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGS 478
I V +LSI L +LGK IT AF+ +Y++T+EL+PT R+ + S R+GS
Sbjct: 413 LFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGS 472
Query: 479 IVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
I+AP L Y + LP ++ G ++ G
Sbjct: 473 IIAPYFVYLGAYNRMLPYIVMGSLTVLIG 501
>AL162582-1|CAI20003.1| 555|Homo sapiens solute carrier family 22
(organic cation transporter), member 2 protein.
Length = 555
Score = 178 bits (434), Expect = 4e-44
Identities = 128/446 (28%), Positives = 203/446 (45%), Gaps = 21/446 (4%)
Query: 105 SADTSFSQEALA-C-DHWIYAN-NNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILG 160
S DT+ S+ L C D W+Y ++IV EFNL C W L + N+G + +G
Sbjct: 109 SLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIG 168
Query: 161 YISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIEL 220
YI+DRFGRK+ L+ + + G L A S +Y +I ++ + + + YIL E
Sbjct: 169 YIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEF 228
Query: 221 LGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIR 280
+G+ R F + ++G + A +A +WR V P FL Y + +PES R
Sbjct: 229 VGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPR 288
Query: 281 WLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMR 340
WL+S N + +EE+ + P + ++R
Sbjct: 289 WLISQNKNAEAMRIIKHIAKKNGKSLPASL-------QRLRLEEETGKKLNPS-FLDLVR 340
Query: 341 SPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDK-YTNYMLXXXXXXXXXXINALVLD 399
+P I K I + W T + ++ GL I + LAGD Y ++ + L +D
Sbjct: 341 TPQIRKHTMILMYNWFTSSVLYQGL-IMHMGLAGDNIYLDFFYSALVEFPAAFMIILTID 399
Query: 400 RIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFP 459
RIGR+ MV G +C A F+ + WL I + LG++ IT A+ + + +EL+P
Sbjct: 400 RIGRRYPWAASNMVAGAACLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYP 459
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQM--PLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXX 517
T R+ + CS + IG I+ P + L I+++ LP ++FG LVAG
Sbjct: 460 TFIRNLGVHICSSMCDIGGIITPFLVYRLTNIWLE-LPLMVFGVLGLVAGGLVLLLPETK 518
Query: 518 XXXXXXXIQEAEQIATRHREPHKSKE 543
I+EAE + + P K+KE
Sbjct: 519 GKALPETIEEAENM----QRPRKNKE 540
>AB007448-1|BAA23356.1| 551|Homo sapiens OCTN1 protein.
Length = 551
Score = 177 bits (431), Expect = 8e-44
Identities = 135/509 (26%), Positives = 233/509 (45%), Gaps = 28/509 (5%)
Query: 17 DVDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTD 76
D D V+ LG+ G F G + +FLAG+ +RC VP+ +L++
Sbjct: 3 DYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSSAW 62
Query: 77 FNPVWLPNAAVEGQG--ERCSR-RVPLTQPCSA-------DTSFSQ-EALAC-DHWIYAN 124
N +P +G+ CSR R+ SA D Q E +C D W ++
Sbjct: 63 RNNS-VPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQ 121
Query: 125 N---NTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVG 180
+ +T+V E+NL C++ WK L ++ +G+L+ + G +SDRFGRK L + +
Sbjct: 122 DVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQT 181
Query: 181 VIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIV--IS 238
L+ FS+S+EM+ ++ + + S + ++IL E+LG+ R++ + LG+ +
Sbjct: 182 GFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFST-LGVCTFFA 240
Query: 239 MGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXX 298
+G + L A + WR +L + P +L + +F+PES RWL+S
Sbjct: 241 VGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKA 300
Query: 299 XXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITC 358
MNN ++EE ++ + + R+ I + W+
Sbjct: 301 AKMNNTAVPAVIF--------DSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLT 352
Query: 359 TFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSC 418
+ ++ L++++ +L GD Y N L L+L + R+ + G
Sbjct: 353 SVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVL 412
Query: 419 CAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGS 478
I V +LSI L +LGK IT AF+ +Y++T+EL+PT R+ + S R+GS
Sbjct: 413 LFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGS 472
Query: 479 IVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
I+AP L Y + LP ++ G ++ G
Sbjct: 473 IIAPYFVYLGAYNRMLPYIVMGSLTVLIG 501
>U77086-1|AAB67703.1| 554|Homo sapiens organic cation transporter 1
protein.
Length = 554
Score = 173 bits (421), Expect = 1e-42
Identities = 135/542 (24%), Positives = 230/542 (42%), Gaps = 36/542 (6%)
Query: 18 VDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTT-D 76
VD +L Q+G++G F + + +FL + + C P L+
Sbjct: 4 VDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCG 63
Query: 77 FNPVWLPNAAVEGQGERCSRRVPLTQPCSADTSFSQEALAC------------------- 117
++P N V G G + L Q + ++Q AL+C
Sbjct: 64 WSPAEELNYTVPGLGP--AGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPC 121
Query: 118 -DHWIYAN-NNTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D W+Y ++IV EFNL C + WK L + N G L +GY +DRFGRK+ L+
Sbjct: 122 QDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLG 181
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
+ + V G L AFS +Y ++ L+ + + A Y L E +G R
Sbjct: 182 TVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQ 241
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
+ ++G V +A +WR L V P LFL Y + +PES RWLLS
Sbjct: 242 MAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKI 301
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
N K ++EE + P ++ + R+P + KR I +
Sbjct: 302 MDHIAQKNGKLPPADL-------KMLSLEEDVTEKLSPS-FADLFRTPRLRKRTFILMYL 353
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T + ++ GL ++ + +G+ Y +++ I + +DR+GR + + ++
Sbjct: 354 WFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLA 413
Query: 415 GVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVG 474
G +C + F+ + WL+I + +G++ IT A I + +EL+PT R+ + CS +
Sbjct: 414 GAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLC 473
Query: 475 RIGSIVAP--QMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIA 532
IG I+ P L E++ + LP +LF L+A +++AE +
Sbjct: 474 DIGGIITPFIVFRLREVW-QALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLG 532
Query: 533 TR 534
+
Sbjct: 533 RK 534
>BC012325-1|AAH12325.1| 557|Homo sapiens solute carrier family 22
(organic cation transporter), member 5 protein.
Length = 557
Score = 173 bits (421), Expect = 1e-42
Identities = 132/507 (26%), Positives = 235/507 (46%), Gaps = 26/507 (5%)
Query: 17 DVDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTD 76
D D V LG+ G F G + +FL + +RC VP+ +L++
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSSAW 62
Query: 77 FNPVWLPNAAVEGQG--ERCSR-RVPLTQPCSA-------DTSFSQ-EALAC-DHWIYAN 124
N +P +G+ C R R+ SA D Q E +C D W ++
Sbjct: 63 RNHT-VPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDVDLGQLEQESCPDGWEFSQ 121
Query: 125 N---NTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVG 180
+ +TIV E+NL C++ WK L ++ +G+L+ I G +SDRFGRK L ++ +
Sbjct: 122 DVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQT 181
Query: 181 VIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVL-TTAFLGIVISM 239
L+ FS ++EM+V++ L + S + A+++L E+LG+ R++ +T + I +
Sbjct: 182 GFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAF 241
Query: 240 GGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXX 299
G + L A + WR ++ + P +L ++ +F+PES RWL+S
Sbjct: 242 GYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAA 301
Query: 300 XMNN-VXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITC 358
N V D ++ I + W+ +R IM + W+T
Sbjct: 302 KANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWN--IRMVTIMSIML-----WMTI 354
Query: 359 TFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSC 418
+ ++GL++++ +L GD + N L + L+L + R+ S+ + G
Sbjct: 355 SVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVL 414
Query: 419 CAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGS 478
+ V + +L+ L ++GK +T AF+ +Y+YT+EL+PT R+ + S R+GS
Sbjct: 415 LFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGS 474
Query: 479 IVAPQMPLLEIYVKWLPSVLFGCTALV 505
I++P L Y ++LP +L G ++
Sbjct: 475 ILSPYFVYLGAYDRFLPYILMGSLTIL 501
>AL353625-3|CAH72016.1| 554|Homo sapiens solute carrier family 22
(organic cation transporter), member 1 protein.
Length = 554
Score = 173 bits (421), Expect = 1e-42
Identities = 135/542 (24%), Positives = 230/542 (42%), Gaps = 36/542 (6%)
Query: 18 VDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTT-D 76
VD +L Q+G++G F + + +FL + + C P L+
Sbjct: 4 VDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCG 63
Query: 77 FNPVWLPNAAVEGQGERCSRRVPLTQPCSADTSFSQEALAC------------------- 117
++P N V G G + L Q + ++Q AL+C
Sbjct: 64 WSPAEELNYTVPGLGP--AGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPC 121
Query: 118 -DHWIYAN-NNTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D W+Y ++IV EFNL C + WK L + N G L +GY +DRFGRK+ L+
Sbjct: 122 QDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLG 181
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
+ + V G L AFS +Y ++ L+ + + A Y L E +G R
Sbjct: 182 TVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQ 241
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
+ ++G V +A +WR L V P LFL Y + +PES RWLLS
Sbjct: 242 MAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKI 301
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
N K ++EE + P ++ + R+P + KR I +
Sbjct: 302 MDHIAQKNGKLPPADL-------KMLSLEEDVTEKLSPS-FADLFRTPRLRKRTFILMYL 353
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T + ++ GL ++ + +G+ Y +++ I + +DR+GR + + ++
Sbjct: 354 WFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLA 413
Query: 415 GVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVG 474
G +C + F+ + WL+I + +G++ IT A I + +EL+PT R+ + CS +
Sbjct: 414 GAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLC 473
Query: 475 RIGSIVAP--QMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIA 532
IG I+ P L E++ + LP +LF L+A +++AE +
Sbjct: 474 DIGGIITPFIVFRLREVW-QALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLG 532
Query: 533 TR 534
+
Sbjct: 533 RK 534
>AF057164-1|AAC24828.1| 557|Homo sapiens organic cation transporter
OCTN2 protein.
Length = 557
Score = 173 bits (421), Expect = 1e-42
Identities = 132/507 (26%), Positives = 235/507 (46%), Gaps = 26/507 (5%)
Query: 17 DVDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTD 76
D D V LG+ G F G + +FL + +RC VP+ +L++
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSSAW 62
Query: 77 FNPVWLPNAAVEGQG--ERCSR-RVPLTQPCSA-------DTSFSQ-EALAC-DHWIYAN 124
N +P +G+ C R R+ SA D Q E +C D W ++
Sbjct: 63 RNHT-VPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQ 121
Query: 125 N---NTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVG 180
+ +TIV E+NL C++ WK L ++ +G+L+ I G +SDRFGRK L ++ +
Sbjct: 122 DVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQT 181
Query: 181 VIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVL-TTAFLGIVISM 239
L+ FS ++EM+V++ L + S + A+++L E+LG+ R++ +T + I +
Sbjct: 182 GFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAF 241
Query: 240 GGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXX 299
G + L A + WR ++ + P +L ++ +F+PES RWL+S
Sbjct: 242 GYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAA 301
Query: 300 XMNN-VXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITC 358
N V D ++ I + W+ +R IM + W+T
Sbjct: 302 KANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWN--IRMVTIMSIML-----WMTI 354
Query: 359 TFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSC 418
+ ++GL++++ +L GD + N L + L+L + R+ S+ + G
Sbjct: 355 SVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVL 414
Query: 419 CAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGS 478
+ V + +L+ L ++GK +T AF+ +Y+YT+EL+PT R+ + S R+GS
Sbjct: 415 LFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGS 474
Query: 479 IVAPQMPLLEIYVKWLPSVLFGCTALV 505
I++P L Y ++LP +L G ++
Sbjct: 475 ILSPYFVYLGAYDRFLPYILMGSLTIL 501
>AB016625-1|BAA36712.1| 557|Homo sapiens OCTN2 protein.
Length = 557
Score = 173 bits (421), Expect = 1e-42
Identities = 132/507 (26%), Positives = 235/507 (46%), Gaps = 26/507 (5%)
Query: 17 DVDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTD 76
D D V LG+ G F G + +FL + +RC VP+ +L++
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSSAW 62
Query: 77 FNPVWLPNAAVEGQG--ERCSR-RVPLTQPCSA-------DTSFSQ-EALAC-DHWIYAN 124
N +P +G+ C R R+ SA D Q E +C D W ++
Sbjct: 63 RNHT-VPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQ 121
Query: 125 N---NTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVG 180
+ +TIV E+NL C++ WK L ++ +G+L+ I G +SDRFGRK L ++ +
Sbjct: 122 DVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQT 181
Query: 181 VIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVL-TTAFLGIVISM 239
L+ FS ++EM+V++ L + S + A+++L E+LG+ R++ +T + I +
Sbjct: 182 GFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAF 241
Query: 240 GGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXX 299
G + L A + WR ++ + P +L ++ +F+PES RWL+S
Sbjct: 242 GYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAA 301
Query: 300 XMNN-VXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITC 358
N V D ++ I + W+ +R IM + W+T
Sbjct: 302 KANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWN--IRMVTIMSIML-----WMTI 354
Query: 359 TFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSC 418
+ ++GL++++ +L GD + N L + L+L + R+ S+ + G
Sbjct: 355 SVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVL 414
Query: 419 CAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGS 478
+ V + +L+ L ++GK +T AF+ +Y+YT+EL+PT R+ + S R+GS
Sbjct: 415 LFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGS 474
Query: 479 IVAPQMPLLEIYVKWLPSVLFGCTALV 505
I++P L Y ++LP +L G ++
Sbjct: 475 ILSPYFVYLGAYDRFLPYILMGSLTIL 501
>AB015050-1|BAA29023.1| 557|Homo sapiens OCTN2 protein.
Length = 557
Score = 173 bits (421), Expect = 1e-42
Identities = 132/507 (26%), Positives = 235/507 (46%), Gaps = 26/507 (5%)
Query: 17 DVDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTD 76
D D V LG+ G F G + +FL + +RC VP+ +L++
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSSAW 62
Query: 77 FNPVWLPNAAVEGQG--ERCSR-RVPLTQPCSA-------DTSFSQ-EALAC-DHWIYAN 124
N +P +G+ C R R+ SA D Q E +C D W ++
Sbjct: 63 RNHT-VPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQ 121
Query: 125 N---NTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVG 180
+ +TIV E+NL C++ WK L ++ +G+L+ I G +SDRFGRK L ++ +
Sbjct: 122 DVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQT 181
Query: 181 VIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVL-TTAFLGIVISM 239
L+ FS ++EM+V++ L + S + A+++L E+LG+ R++ +T + I +
Sbjct: 182 GFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAF 241
Query: 240 GGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXX 299
G + L A + WR ++ + P +L ++ +F+PES RWL+S
Sbjct: 242 GYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAA 301
Query: 300 XMNN-VXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITC 358
N V D ++ I + W+ +R IM + W+T
Sbjct: 302 KANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWN--IRMVTIMSIML-----WMTI 354
Query: 359 TFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSC 418
+ ++GL++++ +L GD + N L + L+L + R+ S+ + G
Sbjct: 355 SVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVL 414
Query: 419 CAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGS 478
+ V + +L+ L ++GK +T AF+ +Y+YT+EL+PT R+ + S R+GS
Sbjct: 415 LFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGS 474
Query: 479 IVAPQMPLLEIYVKWLPSVLFGCTALV 505
I++P L Y ++LP +L G ++
Sbjct: 475 ILSPYFVYLGAYDRFLPYILMGSLTIL 501
>X98332-1|CAA66977.1| 554|Homo sapiens organic cation transporter
protein.
Length = 554
Score = 171 bits (417), Expect = 4e-42
Identities = 134/542 (24%), Positives = 229/542 (42%), Gaps = 36/542 (6%)
Query: 18 VDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTT-D 76
VD +L Q+G++G F + + +FL + + C P L+
Sbjct: 4 VDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCG 63
Query: 77 FNPVWLPNAAVEGQGERCSRRVPLTQPCSADTSFSQEALAC------------------- 117
++P N V G G + L Q + ++Q AL+C
Sbjct: 64 WSPAEELNYTVPGLGP--AGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPC 121
Query: 118 -DHWIYAN-NNTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D W+Y ++IV EFNL C + WK L + N G +GY +DRFGRK+ L+
Sbjct: 122 QDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFFFGSLGVGYFADRFGRKLCLLG 181
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
+ + V G L AFS +Y ++ L+ + + A Y L E +G R
Sbjct: 182 TVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQ 241
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
+ ++G V +A +WR L V P LFL Y + +PES RWLLS
Sbjct: 242 MAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKI 301
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
N K ++EE + P ++ + R+P + KR I +
Sbjct: 302 MDHIAQKNGKLPPADL-------KMLSLEEDVTEKLSPS-FADLFRTPRLRKRTFILMYL 353
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T + ++ GL ++ + +G+ Y +++ I + +DR+GR + + ++
Sbjct: 354 WFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLA 413
Query: 415 GVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVG 474
G +C + F+ + WL+I + +G++ IT A I + +EL+PT R+ + CS +
Sbjct: 414 GAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLC 473
Query: 475 RIGSIVAP--QMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIA 532
IG I+ P L E++ + LP +LF L+A +++AE +
Sbjct: 474 DIGGIITPFIVFRLREVW-QALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLG 532
Query: 533 TR 534
+
Sbjct: 533 RK 534
>BC126364-1|AAI26365.1| 554|Homo sapiens solute carrier family 22
(organic cation transporter), member 1 protein.
Length = 554
Score = 171 bits (417), Expect = 4e-42
Identities = 134/542 (24%), Positives = 229/542 (42%), Gaps = 36/542 (6%)
Query: 18 VDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTT-D 76
VD +L Q+G++G F + + +FL + + C P L+
Sbjct: 4 VDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCG 63
Query: 77 FNPVWLPNAAVEGQGERCSRRVPLTQPCSADTSFSQEALAC------------------- 117
++P N V G G + L Q + ++Q AL+C
Sbjct: 64 WSPAEELNYTVPGLGP--AGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPC 121
Query: 118 -DHWIYAN-NNTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D W+Y ++IV EFNL C + WK L + N G +GY +DRFGRK+ L+
Sbjct: 122 QDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFFFGSLGVGYFADRFGRKLCLLG 181
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
+ + V G L AFS +Y ++ L+ + + A Y L E +G R
Sbjct: 182 TVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQ 241
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
+ ++G V +A +WR L V P LFL Y + +PES RWLLS
Sbjct: 242 MAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKI 301
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
N K ++EE + P ++ + R+P + KR I +
Sbjct: 302 MDHIAQKNGKLPPADL-------KMLSLEEDVTEKLSPS-FADLFRTPRLRKRTFILMYL 353
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T + ++ GL ++ + +G+ Y +++ I + +DR+GR + + ++
Sbjct: 354 WFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLA 413
Query: 415 GVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVG 474
G +C + F+ + WL+I + +G++ IT A I + +EL+PT R+ + CS +
Sbjct: 414 GAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLC 473
Query: 475 RIGSIVAP--QMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIA 532
IG I+ P L E++ + LP +LF L+A +++AE +
Sbjct: 474 DIGGIITPFIVFRLREVW-QALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLG 532
Query: 533 TR 534
+
Sbjct: 533 RK 534
>AJ243995-1|CAB95971.1| 554|Homo sapiens protein ( Homo sapiens
partial oct1 gene for organic cation transporter, exon 1
and joined CDS. ).
Length = 554
Score = 169 bits (411), Expect = 2e-41
Identities = 134/542 (24%), Positives = 229/542 (42%), Gaps = 36/542 (6%)
Query: 18 VDRVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTT-D 76
VD +L Q+G++G F + + +FL + + C P L+
Sbjct: 4 VDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCG 63
Query: 77 FNPVWLPNAAVEGQGERCSRRVPLTQPCSADTSFSQEALAC------------------- 117
++P N V G G + L Q + ++Q AL+C
Sbjct: 64 WSPAEELNYTVPGLGP--AGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPC 121
Query: 118 -DHWIYAN-NNTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D W+Y ++IV EFNL C + WK L + N G L +GY +DRFGRK+ L+
Sbjct: 122 QDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLG 181
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
+ + V G L AFS +Y ++ L+ + + A Y L E +G R
Sbjct: 182 TVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQ 241
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
+ ++G V +A +WR L V P LFL Y + +PES RWLLS
Sbjct: 242 MAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKI 301
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
N K ++EE + P ++ + R+ + KR I +
Sbjct: 302 MDHIAQKNGKLPPADL-------KMLSLEEDVTEKLSPS-FADLFRTLRLRKRTFILMYL 353
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T + ++ GL ++ + +G+ Y +++ I + +DR+GR + + ++
Sbjct: 354 WFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLA 413
Query: 415 GVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVG 474
G +C + F+ + WL+I + +G++ IT A I + +EL+PT R+ + CS +
Sbjct: 414 GAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLC 473
Query: 475 RIGSIVAP--QMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIA 532
IG I+ P L E++ + LP +LF L+A +++AE +
Sbjct: 474 DIGGIITPFIVFRLREVW-QALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLG 532
Query: 533 TR 534
+
Sbjct: 533 RK 534
>BC022387-1|AAH22387.1| 542|Homo sapiens solute carrier family 22
(organic anion transporter), member 8 protein.
Length = 542
Score = 161 bits (390), Expect = 8e-39
Identities = 122/529 (23%), Positives = 222/529 (41%), Gaps = 14/529 (2%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L ++G G F + IF A + + C P S
Sbjct: 6 ILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGP------ 59
Query: 81 WLPNAAVEGQGERCSRRV-PLTQPCSADTSFSQEALACDHWIY-ANNNTIVAEFNLACQE 138
W+ G+ ERC R V P DT + E D W+Y + ++IV E++L C
Sbjct: 60 WVLPMGPNGKPERCLRFVHPPNASLPNDTQRAMEP-CLDGWVYNSTKDSIVTEWDLVCNS 118
Query: 139 WK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVI 197
K + + +I G+L+ +LG +SDRFGR+ L S L+ G+ AFS ++ +Y++
Sbjct: 119 NKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMV 178
Query: 198 VEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTF 257
FL + ++ IL +E + R + + LG + G +A WR
Sbjct: 179 FRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWL 238
Query: 258 ILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXD 317
L V P +F ++ PESIRWL+ N +
Sbjct: 239 QLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNG--KKEEGERLSLEE 296
Query: 318 KPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAIC-SWWWITCTFVFYGLAINSVSLAGDK 376
++++ + S + R P +++R+ C S W F +Y LA+ +
Sbjct: 297 LKLNLQKEISLAKAKYTASDLFRIP-MLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNL 355
Query: 377 YTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLY 436
Y ++ I L L +GR + ++ G + A+ FV + + L
Sbjct: 356 YILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALTFVPLDLQTVRTVLA 415
Query: 437 LLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPS 496
+ GK ++ +F+ +++YTSEL+PT R + + ++ R+GS+V+P + + ++P+
Sbjct: 416 VFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPN 475
Query: 497 VLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIATRHREPHKSKEIQ 545
+++G TAL+ G I++ E + R ++P + E++
Sbjct: 476 IIYGITALLGGSAALFLPETLNQPLPETIEDLENWSLRAKKPKQEPEVE 524
>AB042505-1|BAB47393.1| 542|Homo sapiens organic anion transporter
3 protein.
Length = 542
Score = 161 bits (390), Expect = 8e-39
Identities = 122/529 (23%), Positives = 222/529 (41%), Gaps = 14/529 (2%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L ++G G F + IF A + + C P S
Sbjct: 6 ILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGP------ 59
Query: 81 WLPNAAVEGQGERCSRRV-PLTQPCSADTSFSQEALACDHWIY-ANNNTIVAEFNLACQE 138
W+ G+ ERC R V P DT + E D W+Y + ++IV E++L C
Sbjct: 60 WVLPMGPNGKPERCLRFVHPPNASLPNDTQRAMEP-CLDGWVYNSTKDSIVTEWDLVCNS 118
Query: 139 WK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVI 197
K + + +I G+L+ +LG +SDRFGR+ L S L+ G+ AFS ++ +Y++
Sbjct: 119 NKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMV 178
Query: 198 VEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTF 257
FL + ++ IL +E + R + + LG + G +A WR
Sbjct: 179 FRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWL 238
Query: 258 ILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXD 317
L V P +F ++ PESIRWL+ N +
Sbjct: 239 QLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSEALKILRRVAVFNG--KKEEGERLSLEE 296
Query: 318 KPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAIC-SWWWITCTFVFYGLAINSVSLAGDK 376
++++ + S + R P +++R+ C S W F +Y LA+ +
Sbjct: 297 LKLNLQKEISLAKAKYTASDLFRIP-MLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNL 355
Query: 377 YTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLY 436
Y ++ I L L +GR + ++ G + A+ FV + + L
Sbjct: 356 YILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALTFVPLDLQTVRTVLA 415
Query: 437 LLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPS 496
+ GK ++ +F+ +++YTSEL+PT R + + ++ R+GS+V+P + + ++P+
Sbjct: 416 VFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPN 475
Query: 497 VLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIATRHREPHKSKEIQ 545
+++G TAL+ G I++ E + R ++P + E++
Sbjct: 476 IIYGITALLGGSAALFLPETLNQPLPETIEDLENWSLRAKKPKQEPEVE 524
>AB291606-1|BAF45812.1| 581|Homo sapiens organic cation transporter
2 splice variant protein.
Length = 581
Score = 157 bits (380), Expect = 1e-37
Identities = 100/379 (26%), Positives = 186/379 (49%), Gaps = 10/379 (2%)
Query: 130 AEFNLACQE-WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAF 188
A++NL C++ WK L ++ +G+L+ I G +SDRFGRK L ++ + L+ F
Sbjct: 154 AQWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIF 213
Query: 189 SVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVL-TTAFLGIVISMGGVCFALM 247
S ++EM+V++ L + S + A+++L E+LG+ R++ +T + I + G + L
Sbjct: 214 SKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLF 273
Query: 248 AKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNN-VXX 306
A + WR ++ + P +L ++ +F+PES RWL+S N V
Sbjct: 274 AYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVP 333
Query: 307 XXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLA 366
D ++ I + W+ +R IM + W+T + ++GL+
Sbjct: 334 STIFDPSELQDLSSKKQQSHNILDLLRTWN--IRMVTIMSIML-----WMTISVGYFGLS 386
Query: 367 INSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRN 426
+++ +L GD + N L + L+L + R+ S+ + G + V
Sbjct: 387 LDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPP 446
Query: 427 HIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPL 486
+ +L+ L ++GK +T AF+ +Y+YT+EL+PT R+ + S R+GSI++P
Sbjct: 447 DLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVY 506
Query: 487 LEIYVKWLPSVLFGCTALV 505
L Y ++LP +L G ++
Sbjct: 507 LGAYDRFLPYILMGSLTIL 525
>BC047565-1|AAH47565.1| 577|Homo sapiens solute carrier family 22
(organic cation transporter), member 16 protein.
Length = 577
Score = 156 bits (378), Expect = 2e-37
Identities = 120/481 (24%), Positives = 209/481 (43%), Gaps = 16/481 (3%)
Query: 76 DFNPVWLPNAAVEGQGERCSR-RVPLTQPCSADTSFSQEALAC-DHWIYANN---NTIVA 130
D+ V L N + + RCSR + T + + S++ C D +IY N +T V
Sbjct: 84 DYVTVQLQNGEI-WELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVT 142
Query: 131 EFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
++NL C ++W L+ + G+L+ GY SDR GR+V L + + + + G AF+
Sbjct: 143 QWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFA 202
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK 249
V Y ++ F + + ++ +E +G R + L ++G + AL
Sbjct: 203 VDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGY 262
Query: 250 TFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXX 309
+ W + +++ + F+ + LPE+ WLLS N
Sbjct: 263 LVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKL 322
Query: 310 XXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINS 369
+ E+Q S + + I KR W T + FY ++NS
Sbjct: 323 SELLSLDLQGPVSNSPTEVQKHN--LSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNS 380
Query: 370 VSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFV--RNH 427
V+L G++Y N L + +D++GR R++L + C C + V + H
Sbjct: 381 VNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGR-RTVLAYSLFCSALACGVVMVIPQKH 439
Query: 428 IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAP-QMPL 486
+ L + ++GK AI AF IY+YT+EL+PT R + SMV R+ SI+AP + L
Sbjct: 440 YI-LGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDL 498
Query: 487 LEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIATRHREPHKSKEIQS 546
I++ ++P + G AL++G +EA ++ + + E SK + +
Sbjct: 499 SSIWI-FIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESEN-ESKSSKLLLT 556
Query: 547 T 547
T
Sbjct: 557 T 557
>AL050350-4|CAI42512.1| 577|Homo sapiens solute carrier family 22
(organic cation transporter), member 16 protein.
Length = 577
Score = 156 bits (378), Expect = 2e-37
Identities = 120/481 (24%), Positives = 209/481 (43%), Gaps = 16/481 (3%)
Query: 76 DFNPVWLPNAAVEGQGERCSR-RVPLTQPCSADTSFSQEALAC-DHWIYANN---NTIVA 130
D+ V L N + + RCSR + T + + S++ C D +IY N +T V
Sbjct: 84 DYVTVQLQNGEI-WELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVT 142
Query: 131 EFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
++NL C ++W L+ + G+L+ GY SDR GR+V L + + + + G AF+
Sbjct: 143 QWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFA 202
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK 249
V Y ++ F + + ++ +E +G R + L ++G + AL
Sbjct: 203 VDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGY 262
Query: 250 TFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXX 309
+ W + +++ + F+ + LPE+ WLLS N
Sbjct: 263 LVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKL 322
Query: 310 XXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINS 369
+ E+Q S + + I KR W T + FY ++NS
Sbjct: 323 SELLSLDLQGPVSNSPTEVQKHN--LSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNS 380
Query: 370 VSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFV--RNH 427
V+L G++Y N L + +D++GR R++L + C C + V + H
Sbjct: 381 VNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGR-RTVLAYSLFCSALACGVVMVIPQKH 439
Query: 428 IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAP-QMPL 486
+ L + ++GK AI AF IY+YT+EL+PT R + SMV R+ SI+AP + L
Sbjct: 440 YI-LGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDL 498
Query: 487 LEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIATRHREPHKSKEIQS 546
I++ ++P + G AL++G +EA ++ + + E SK + +
Sbjct: 499 SSIWI-FIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESEN-ESKSSKLLLT 556
Query: 547 T 547
T
Sbjct: 557 T 557
>BC033682-1|AAH33682.1| 550|Homo sapiens solute carrier family 22
(organic anion transporter), member 6 protein.
Length = 550
Score = 155 bits (375), Expect = 5e-37
Identities = 117/496 (23%), Positives = 203/496 (40%), Gaps = 14/496 (2%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L Q+G G+F +T F A + C P +L+ V
Sbjct: 6 LLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65
Query: 81 WLPNAAVEGQGERCSR------RVPLTQPCSADTSFSQEALACDHWIYANN---NTIVAE 131
WLP +GQ E C R +P A+ + + E D WIY N+ +TIV E
Sbjct: 66 WLPRDR-QGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCT-DGWIYDNSTFPSTIVTE 123
Query: 132 FNLACQEWK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV 190
++L C R L +++ +G+L+ + GY++DR GR+ LIL+ V GT AF+
Sbjct: 124 WDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAP 183
Query: 191 SYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
++ +Y L +A A L +E + R +G V S+G A +A
Sbjct: 184 NFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYA 243
Query: 251 FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXX 310
+WR L+V P F Y +F ES RW S +N
Sbjct: 244 VPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAK 303
Query: 311 XXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSV 370
+++++ + +++R P + S W +F +YGL ++
Sbjct: 304 LSMEVL--RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQ 361
Query: 371 SLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVW 430
Y ++ + LV++ +GR+ + + ++ G+ +
Sbjct: 362 GFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421
Query: 431 LSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIY 490
+ L +LGK + +FN I++YT EL+PT R + + S + R+GSIV+P + +
Sbjct: 422 VRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAEL 481
Query: 491 VKWLPSVLFGCTALVA 506
+P ++G + A
Sbjct: 482 YPSMPLFIYGAVPVAA 497
>AJ249369-1|CAB77184.1| 563|Homo sapiens organic anion transporter
protein.
Length = 563
Score = 155 bits (375), Expect = 5e-37
Identities = 117/496 (23%), Positives = 203/496 (40%), Gaps = 14/496 (2%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L Q+G G+F +T F A + C P +L+ V
Sbjct: 6 LLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65
Query: 81 WLPNAAVEGQGERCSR------RVPLTQPCSADTSFSQEALACDHWIYANN---NTIVAE 131
WLP +GQ E C R +P A+ + + E D WIY N+ +TIV E
Sbjct: 66 WLPRDR-QGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCT-DGWIYDNSTFPSTIVTE 123
Query: 132 FNLACQEWK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV 190
++L C R L +++ +G+L+ + GY++DR GR+ LIL+ V GT AF+
Sbjct: 124 WDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAP 183
Query: 191 SYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
++ +Y L +A A L +E + R +G V S+G A +A
Sbjct: 184 NFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYA 243
Query: 251 FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXX 310
+WR L+V P F Y +F ES RW S +N
Sbjct: 244 VPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAK 303
Query: 311 XXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSV 370
+++++ + +++R P + S W +F +YGL ++
Sbjct: 304 LSMEVL--RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQ 361
Query: 371 SLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVW 430
Y ++ + LV++ +GR+ + + ++ G+ +
Sbjct: 362 GFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421
Query: 431 LSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIY 490
+ L +LGK + +FN I++YT EL+PT R + + S + R+GSIV+P + +
Sbjct: 422 VRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAEL 481
Query: 491 VKWLPSVLFGCTALVA 506
+P ++G + A
Sbjct: 482 YPSMPLFIYGAVPVAA 497
>AF268892-1|AAK58593.1| 577|Homo sapiens organic cation transporter
OKB1 protein.
Length = 577
Score = 155 bits (375), Expect = 5e-37
Identities = 120/481 (24%), Positives = 208/481 (43%), Gaps = 16/481 (3%)
Query: 76 DFNPVWLPNAAVEGQGERCSR-RVPLTQPCSADTSFSQEALAC-DHWIYANN---NTIVA 130
D+ V L N + + RCSR + T + + S++ C D +IY N +T V
Sbjct: 84 DYVTVQLQNGEI-WELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVT 142
Query: 131 EFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
++NL C ++W L+ + G+L+ GY SDR GR+V L + + + + G AF+
Sbjct: 143 QWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFA 202
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK 249
V Y ++ F + + ++ +E +G R + L ++G + AL
Sbjct: 203 VDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGY 262
Query: 250 TFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXX 309
+ W + +++ + F+ + LPE+ WLLS N
Sbjct: 263 LVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKL 322
Query: 310 XXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINS 369
+ E+Q S + + I KR W T + FY ++NS
Sbjct: 323 SELLSLDLQGPVSNSPTEVQKHN--LSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNS 380
Query: 370 VSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFV--RNH 427
V+L G++Y N L + D++GR R++L + C C + V + H
Sbjct: 381 VNLGGNEYLNLFLLGVVEIPAYTFVCIATDKVGR-RTVLAYSLFCSALACGVVMVIPQKH 439
Query: 428 IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAP-QMPL 486
+ L + ++GK AI AF IY+YT+EL+PT R + SMV R+ SI+AP + L
Sbjct: 440 YI-LGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDL 498
Query: 487 LEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIATRHREPHKSKEIQS 546
I++ ++P + G AL++G +EA ++ + + E SK + +
Sbjct: 499 SSIWI-FIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESEN-ESKSSKLLLT 556
Query: 547 T 547
T
Sbjct: 557 T 557
>AF124373-1|AAD55356.1| 550|Homo sapiens organic anion transporter
1 protein.
Length = 550
Score = 155 bits (375), Expect = 5e-37
Identities = 117/496 (23%), Positives = 203/496 (40%), Gaps = 14/496 (2%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L Q+G G+F +T F A + C P +L+ V
Sbjct: 6 LLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65
Query: 81 WLPNAAVEGQGERCSR------RVPLTQPCSADTSFSQEALACDHWIYANN---NTIVAE 131
WLP +GQ E C R +P A+ + + E D WIY N+ +TIV E
Sbjct: 66 WLPRDR-QGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCT-DGWIYDNSTFPSTIVTE 123
Query: 132 FNLACQEWK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV 190
++L C R L +++ +G+L+ + GY++DR GR+ LIL+ V GT AF+
Sbjct: 124 WDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAP 183
Query: 191 SYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
++ +Y L +A A L +E + R +G V S+G A +A
Sbjct: 184 NFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYA 243
Query: 251 FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXX 310
+WR L+V P F Y +F ES RW S +N
Sbjct: 244 VPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAK 303
Query: 311 XXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSV 370
+++++ + +++R P + S W +F +YGL ++
Sbjct: 304 LSMEVL--RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQ 361
Query: 371 SLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVW 430
Y ++ + LV++ +GR+ + + ++ G+ +
Sbjct: 362 GFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421
Query: 431 LSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIY 490
+ L +LGK + +FN I++YT EL+PT R + + S + R+GSIV+P + +
Sbjct: 422 VRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAEL 481
Query: 491 VKWLPSVLFGCTALVA 506
+P ++G + A
Sbjct: 482 YPSMPLFIYGAVPVAA 497
>AF097490-1|AAD19356.1| 550|Homo sapiens organic anion transporter
1 protein.
Length = 550
Score = 155 bits (375), Expect = 5e-37
Identities = 117/496 (23%), Positives = 203/496 (40%), Gaps = 14/496 (2%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L Q+G G+F +T F A + C P +L+ V
Sbjct: 6 LLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65
Query: 81 WLPNAAVEGQGERCSR------RVPLTQPCSADTSFSQEALACDHWIYANN---NTIVAE 131
WLP +GQ E C R +P A+ + + E D WIY N+ +TIV E
Sbjct: 66 WLPRDR-QGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCT-DGWIYDNSTFPSTIVTE 123
Query: 132 FNLACQEWK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV 190
++L C R L +++ +G+L+ + GY++DR GR+ LIL+ V GT AF+
Sbjct: 124 WDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAP 183
Query: 191 SYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
++ +Y L +A A L +E + R +G V S+G A +A
Sbjct: 184 NFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYA 243
Query: 251 FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXX 310
+WR L+V P F Y +F ES RW S +N
Sbjct: 244 VPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAK 303
Query: 311 XXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSV 370
+++++ + +++R P + S W +F +YGL ++
Sbjct: 304 LSMEVL--RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQ 361
Query: 371 SLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVW 430
Y ++ + LV++ +GR+ + + ++ G+ +
Sbjct: 362 GFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421
Query: 431 LSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIY 490
+ L +LGK + +FN I++YT EL+PT R + + S + R+GSIV+P + +
Sbjct: 422 VRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAEL 481
Query: 491 VKWLPSVLFGCTALVA 506
+P ++G + A
Sbjct: 482 YPSMPLFIYGAVPVAA 497
>AF057039-1|AAC70004.1| 550|Homo sapiens putative renal organic
anion transporter 1 protein.
Length = 550
Score = 155 bits (375), Expect = 5e-37
Identities = 117/496 (23%), Positives = 203/496 (40%), Gaps = 14/496 (2%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L Q+G G+F +T F A + C P +L+ V
Sbjct: 6 LLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65
Query: 81 WLPNAAVEGQGERCSR------RVPLTQPCSADTSFSQEALACDHWIYANN---NTIVAE 131
WLP +GQ E C R +P A+ + + E D WIY N+ +TIV E
Sbjct: 66 WLPRDR-QGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCT-DGWIYDNSTFPSTIVTE 123
Query: 132 FNLACQEWK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV 190
++L C R L +++ +G+L+ + GY++DR GR+ LIL+ V GT AF+
Sbjct: 124 WDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAP 183
Query: 191 SYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
++ +Y L +A A L +E + R +G V S+G A +A
Sbjct: 184 NFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYA 243
Query: 251 FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXX 310
+WR L+V P F Y +F ES RW S +N
Sbjct: 244 VPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAK 303
Query: 311 XXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSV 370
+++++ + +++R P + S W +F +YGL ++
Sbjct: 304 LSMEVL--RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQ 361
Query: 371 SLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVW 430
Y ++ + LV++ +GR+ + + ++ G+ +
Sbjct: 362 GFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421
Query: 431 LSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIY 490
+ L +LGK + +FN I++YT EL+PT R + + S + R+GSIV+P + +
Sbjct: 422 VRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAEL 481
Query: 491 VKWLPSVLFGCTALVA 506
+P ++G + A
Sbjct: 482 YPSMPLFIYGAVPVAA 497
>AB055798-1|BAC23062.1| 543|Homo sapiens carnitine transporter 2
protein.
Length = 543
Score = 155 bits (375), Expect = 5e-37
Identities = 116/464 (25%), Positives = 202/464 (43%), Gaps = 15/464 (3%)
Query: 93 RCSR-RVPLTQPCSADTSFSQEALAC-DHWIYANN---NTIVAEFNLAC-QEWKRTLVGT 146
RCSR + T + + S++ C D +IY N +T V ++NL C ++W L+
Sbjct: 66 RCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQP 125
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAG 206
+ G+L+ GY SDR GR+V L + + + + G AF+V Y ++ F +
Sbjct: 126 LFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVA 185
Query: 207 ASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPAL 266
+ ++ +E +G R + L ++G + AL + W + +++ +
Sbjct: 186 SGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTV 245
Query: 267 LFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKK 326
F+ + LPE+ WLLS N +
Sbjct: 246 PFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPT 305
Query: 327 EIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXX 386
E+Q S + + I KR W T + FY ++NSV+L G++Y N L
Sbjct: 306 EVQKHN--LSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVV 363
Query: 387 XXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFV--RNHIVWLSIFLYLLGKVAIT 444
+ +D++GR R++L + C C + V + H + L + ++GK AI
Sbjct: 364 EIPAYTFVCIAMDKVGR-RTVLAYSLFCSALACGVVMVIPQKHYI-LGVVTAMVGKFAIG 421
Query: 445 QAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAP-QMPLLEIYVKWLPSVLFGCTA 503
AF IY+YT+EL+PT R + SMV R+ SI+AP + L I++ ++P + G A
Sbjct: 422 AAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWI-FIPQLFVGTMA 480
Query: 504 LVAGXXXXXXXXXXXXXXXXXIQEAEQIATRHREPHKSKEIQST 547
L++G +EA ++ + + E SK + +T
Sbjct: 481 LLSGVLTLKLPETLGKRLATTWEEAAKLESEN-ESKSSKLLLTT 523
>AB009698-1|BAA75073.1| 550|Homo sapiens hOAT1-2 protein.
Length = 550
Score = 155 bits (375), Expect = 5e-37
Identities = 117/496 (23%), Positives = 203/496 (40%), Gaps = 14/496 (2%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L Q+G G+F +T F A + C P +L+ V
Sbjct: 6 LLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65
Query: 81 WLPNAAVEGQGERCSR------RVPLTQPCSADTSFSQEALACDHWIYANN---NTIVAE 131
WLP +GQ E C R +P A+ + + E D WIY N+ +TIV E
Sbjct: 66 WLPRDR-QGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCT-DGWIYDNSTFPSTIVTE 123
Query: 132 FNLACQEWK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV 190
++L C R L +++ +G+L+ + GY++DR GR+ LIL+ V GT AF+
Sbjct: 124 WDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAP 183
Query: 191 SYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
++ +Y L +A A L +E + R +G V S+G A +A
Sbjct: 184 NFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYA 243
Query: 251 FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXX 310
+WR L+V P F Y +F ES RW S +N
Sbjct: 244 VPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAK 303
Query: 311 XXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSV 370
+++++ + +++R P + S W +F +YGL ++
Sbjct: 304 LSMEVL--RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQ 361
Query: 371 SLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVW 430
Y ++ + LV++ +GR+ + + ++ G+ +
Sbjct: 362 GFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421
Query: 431 LSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIY 490
+ L +LGK + +FN I++YT EL+PT R + + S + R+GSIV+P + +
Sbjct: 422 VRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAEL 481
Query: 491 VKWLPSVLFGCTALVA 506
+P ++G + A
Sbjct: 482 YPSMPLFIYGAVPVAA 497
>AB009697-1|BAA75072.1| 563|Homo sapiens hOAT1-1 protein.
Length = 563
Score = 155 bits (375), Expect = 5e-37
Identities = 117/496 (23%), Positives = 203/496 (40%), Gaps = 14/496 (2%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L Q+G G+F +T F A + C P +L+ V
Sbjct: 6 LLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65
Query: 81 WLPNAAVEGQGERCSR------RVPLTQPCSADTSFSQEALACDHWIYANN---NTIVAE 131
WLP +GQ E C R +P A+ + + E D WIY N+ +TIV E
Sbjct: 66 WLPRDR-QGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCT-DGWIYDNSTFPSTIVTE 123
Query: 132 FNLACQEWK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV 190
++L C R L +++ +G+L+ + GY++DR GR+ LIL+ V GT AF+
Sbjct: 124 WDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAP 183
Query: 191 SYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
++ +Y L +A A L +E + R +G V S+G A +A
Sbjct: 184 NFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYA 243
Query: 251 FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXX 310
+WR L+V P F Y +F ES RW S +N
Sbjct: 244 VPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAK 303
Query: 311 XXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSV 370
+++++ + +++R P + S W +F +YGL ++
Sbjct: 304 LSMEVL--RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQ 361
Query: 371 SLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVW 430
Y ++ + LV++ +GR+ + + ++ G+ +
Sbjct: 362 GFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421
Query: 431 LSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIY 490
+ L +LGK + +FN I++YT EL+PT R + + S + R+GSIV+P + +
Sbjct: 422 VRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAEL 481
Query: 491 VKWLPSVLFGCTALVA 506
+P ++G + A
Sbjct: 482 YPSMPLFIYGAVPVAA 497
>AY145502-1|AAN52928.1| 577|Homo sapiens putative transmembrane
transporter FLIPT 2 protein.
Length = 577
Score = 154 bits (373), Expect = 9e-37
Identities = 120/481 (24%), Positives = 208/481 (43%), Gaps = 16/481 (3%)
Query: 76 DFNPVWLPNAAVEGQGERCSR-RVPLTQPCSADTSFSQEALAC-DHWIYANN---NTIVA 130
D+ V L N + + RCSR + T + + S++ C D +IY N +T V
Sbjct: 84 DYVTVQLQNGEI-WELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVT 142
Query: 131 EFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
++NL C ++W L+ + G+L+ GY SDR GR+V L + + + + G AF+
Sbjct: 143 QWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFA 202
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK 249
V Y ++ F + + ++ +E +G R + L ++G + AL
Sbjct: 203 VDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLGALTGY 262
Query: 250 TFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXX 309
+ W + +++ + F+ + LPE+ WLLS N
Sbjct: 263 LVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKL 322
Query: 310 XXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINS 369
+ E+Q S + + I KR W T + FY ++NS
Sbjct: 323 SELLSLDLQGPVSNSPTEVQKHN--LSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNS 380
Query: 370 VSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFV--RNH 427
V+L G++Y N L + D++GR R++L + C C + V + H
Sbjct: 381 VNLGGNEYLNLFLLGVVEIPAYTFVCIATDKVGR-RTVLAYSLFCSALACGVVMVIPQKH 439
Query: 428 IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAP-QMPL 486
+ L + ++GK AI AF IY+YT+EL+PT R + SMV R+ SI+AP + L
Sbjct: 440 YI-LGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDL 498
Query: 487 LEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIATRHREPHKSKEIQS 546
I++ ++P + G AL++G +EA ++ + + E SK + +
Sbjct: 499 SSIWI-FIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESEN-ESKSSKLLLT 556
Query: 547 T 547
T
Sbjct: 557 T 557
>BC026358-1|AAH26358.1| 535|Homo sapiens solute carrier family 22
(organic cation transporter), member 15 protein.
Length = 535
Score = 153 bits (372), Expect = 1e-36
Identities = 110/400 (27%), Positives = 181/400 (45%), Gaps = 22/400 (5%)
Query: 119 HWIYANNNTIVAE--FNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSC 176
H ++++ T +A F +A + +K + + G+ V + G +SDRFGRK +
Sbjct: 75 HVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGF 134
Query: 177 TLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIV 236
L + FS SYE + + FL + +++L E +G L + G+
Sbjct: 135 ALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLF 194
Query: 237 ISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXX 296
++G +AL+ + WRT ++V + F+PES RWL S
Sbjct: 195 FAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALY 254
Query: 297 XXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWI 356
N T + + E G + + R +++ I + W
Sbjct: 255 LIAKRNRKLKCTFSL---------THPANRSCR-ETGSFLDLFRYRVLLGHTLILMFIWF 304
Query: 357 TCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDR--IGRKRSLLIGFMVC 414
C+ V+YGL +++ L G Y N L + ++++ GRKR+L +
Sbjct: 305 VCSLVYYGLTLSAGDLGGSIYANLALSGLIEIQSYPLCIYLINQKWFGRKRTLSAFLCLG 364
Query: 415 GVSCCAIPFVRNH------IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLA 468
G++C + F+ V S L LLGK+ I+ AFN +Y+YTSEL+PT R+ L
Sbjct: 365 GLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLG 424
Query: 469 FCSMVGRIGSIVAPQMPLLEIYVKW-LPSVLFGCTALVAG 507
CSM R+G I+AP +P L+ YV+W LP ++FG T L +G
Sbjct: 425 TCSMFSRVGGIIAPFIPSLK-YVQWSLPFIVFGATGLTSG 463
>AY145501-1|AAN52927.1| 547|Homo sapiens putative transmembrane
transporter FLIPT 1 protein.
Length = 547
Score = 153 bits (371), Expect = 2e-36
Identities = 110/400 (27%), Positives = 181/400 (45%), Gaps = 22/400 (5%)
Query: 119 HWIYANNNTIVAE--FNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSC 176
H ++++ T +A F +A + +K + + G+ V + G +SDRFGRK +
Sbjct: 87 HVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGF 146
Query: 177 TLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIV 236
L + FS SYE + + FL + +++L E +G L + G+
Sbjct: 147 ALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLF 206
Query: 237 ISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXX 296
++G +AL+ + WRT ++V + F+PES RWL S
Sbjct: 207 FAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALY 266
Query: 297 XXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWI 356
N T + + E G + + R +++ I + W
Sbjct: 267 LIAKRNRKLKCTFSL---------THPANRSCR-ETGSFLDLFRYRVLLGHTLILMFIWF 316
Query: 357 TCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDR--IGRKRSLLIGFMVC 414
C+ V+YGL +++ L G Y N L + ++++ GRKR+L +
Sbjct: 317 VCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLG 376
Query: 415 GVSCCAIPFVRNH------IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLA 468
G++C + F+ V S L LLGK+ I+ AFN +Y+YTSEL+PT R+ L
Sbjct: 377 GLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLG 436
Query: 469 FCSMVGRIGSIVAPQMPLLEIYVKW-LPSVLFGCTALVAG 507
CSM R+G I+AP +P L+ YV+W LP ++FG T L +G
Sbjct: 437 TCSMFSRVGGIIAPFIPSLK-YVQWSLPFIVFGATGLTSG 475
>AL365318-2|CAH70686.1| 547|Homo sapiens solute carrier family 22
(organic cation transporter), member 15 protein.
Length = 547
Score = 153 bits (371), Expect = 2e-36
Identities = 110/400 (27%), Positives = 181/400 (45%), Gaps = 22/400 (5%)
Query: 119 HWIYANNNTIVAE--FNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSC 176
H ++++ T +A F +A + +K + + G+ V + G +SDRFGRK +
Sbjct: 87 HVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGF 146
Query: 177 TLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIV 236
L + FS SYE + + FL + +++L E +G L + G+
Sbjct: 147 ALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLF 206
Query: 237 ISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXX 296
++G +AL+ + WRT ++V + F+PES RWL S
Sbjct: 207 FAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALY 266
Query: 297 XXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWI 356
N T + + E G + + R +++ I + W
Sbjct: 267 LIAKRNRKLKCTFSL---------THPANRSCR-ETGSFLDLFRYRVLLGHTLILMFIWF 316
Query: 357 TCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDR--IGRKRSLLIGFMVC 414
C+ V+YGL +++ L G Y N L + ++++ GRKR+L +
Sbjct: 317 VCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLG 376
Query: 415 GVSCCAIPFVRNH------IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLA 468
G++C + F+ V S L LLGK+ I+ AFN +Y+YTSEL+PT R+ L
Sbjct: 377 GLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLG 436
Query: 469 FCSMVGRIGSIVAPQMPLLEIYVKW-LPSVLFGCTALVAG 507
CSM R+G I+AP +P L+ YV+W LP ++FG T L +G
Sbjct: 437 TCSMFSRVGGIIAPFIPSLK-YVQWSLPFIVFGATGLTSG 475
>AL357137-2|CAH70380.1| 547|Homo sapiens solute carrier family 22
(organic cation transporter), member 15 protein.
Length = 547
Score = 153 bits (371), Expect = 2e-36
Identities = 110/400 (27%), Positives = 181/400 (45%), Gaps = 22/400 (5%)
Query: 119 HWIYANNNTIVAE--FNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSC 176
H ++++ T +A F +A + +K + + G+ V + G +SDRFGRK +
Sbjct: 87 HVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGF 146
Query: 177 TLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIV 236
L + FS SYE + + FL + +++L E +G L + G+
Sbjct: 147 ALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLF 206
Query: 237 ISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXX 296
++G +AL+ + WRT ++V + F+PES RWL S
Sbjct: 207 FAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALY 266
Query: 297 XXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWI 356
N T + + E G + + R +++ I + W
Sbjct: 267 LIAKRNRKLKCTFSL---------THPANRSCR-ETGSFLDLFRYRVLLGHTLILMFIWF 316
Query: 357 TCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDR--IGRKRSLLIGFMVC 414
C+ V+YGL +++ L G Y N L + ++++ GRKR+L +
Sbjct: 317 VCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLG 376
Query: 415 GVSCCAIPFVRNH------IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLA 468
G++C + F+ V S L LLGK+ I+ AFN +Y+YTSEL+PT R+ L
Sbjct: 377 GLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLG 436
Query: 469 FCSMVGRIGSIVAPQMPLLEIYVKW-LPSVLFGCTALVAG 507
CSM R+G I+AP +P L+ YV+W LP ++FG T L +G
Sbjct: 437 TCSMFSRVGGIIAPFIPSLK-YVQWSLPFIVFGATGLTSG 475
>AF104038-1|AAD10052.1| 550|Homo sapiens para-aminohippurate
transporter protein.
Length = 550
Score = 153 bits (371), Expect = 2e-36
Identities = 112/468 (23%), Positives = 196/468 (41%), Gaps = 15/468 (3%)
Query: 50 HTTYIFLAGSVP-YRCTVPECESLNTTDFNPVWLPNAAVEGQGERCSR------RVPLTQ 102
H T ++P + C P +L+ VWLP +GQ E C R +P
Sbjct: 34 HNTLQNFTAAIPTHHCRPPADANLSKNGGLEVWLPRDR-QGQPESCLRFTSPQWGLPFLN 92
Query: 103 PCSADTSFSQEALACDHWIYANN---NTIVAEFNLACQEWK-RTLVGTIHNIGMLVSLPI 158
A+ + + E D WIY N+ +TIV E++L C R L +++ +G+L+ +
Sbjct: 93 GTEANGTGATEPCT-DGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMV 151
Query: 159 LGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTI 218
GY++DR GR+ LIL+ V GT AF+ ++ +Y L +A A L +
Sbjct: 152 FGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNV 211
Query: 219 ELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPES 278
E + R +G V S+G A +A +WR L+V P F Y +F ES
Sbjct: 212 EWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIES 271
Query: 279 IRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQV 338
RW S +N +++++ + ++
Sbjct: 272 ARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVL--RASLQKELTMGKGQASAMEL 329
Query: 339 MRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVL 398
+R P + S W +F +YGL ++ Y ++ + LV+
Sbjct: 330 LRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVI 389
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
+ +GR+ + + ++ G+ + + L +LGK + +FN I++YT EL+
Sbjct: 390 NSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELY 449
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVA 506
PT R + + S + R+GSIV+P + + +P ++G + A
Sbjct: 450 PTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAA 497
>BC053348-1|AAH53348.1| 553|Homo sapiens solute carrier family 22
(organic anion/cation transporter), member 12 protein.
Length = 553
Score = 150 bits (363), Expect = 1e-35
Identities = 115/441 (26%), Positives = 188/441 (42%), Gaps = 8/441 (1%)
Query: 100 LTQPCSADTSFSQ-EALAC-DHWIYANN---NTIVAEFNLACQEWK-RTLVGTIHNIGML 153
L P + TS+S+ + C D W+Y + +TIVA++NL C + + +I+ G+L
Sbjct: 98 LLDPNATATSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGIL 157
Query: 154 VSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPAS 213
V G SDRFGR++ L S + V+GT AF+ ++ +Y + FL A A +
Sbjct: 158 VGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNT 217
Query: 214 YILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIY 273
L +E R L + S G A +A + W LVV P L Y +
Sbjct: 218 GTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSW 277
Query: 274 FLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPG 333
+L ES RWLL+ +N M E+ + P
Sbjct: 278 WLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVL--LSAMREELSMGQPPA 335
Query: 334 IWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXI 393
++R P + R I + W F F+GLA++ +L + + M
Sbjct: 336 SLGTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMG 395
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMY 453
L+L +GR+ +L ++ G+ A V + + L L +LG + AF I +Y
Sbjct: 396 ALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIY 455
Query: 454 TSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXX 513
+SELFPT R + + M R G+I+ P + LL ++ WLP +++G +++G
Sbjct: 456 SSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLL 515
Query: 514 XXXXXXXXXXXIQEAEQIATR 534
IQ+ + A +
Sbjct: 516 PETQSLPLPDTIQDVQNQAVK 536
>AC044790-2|AAK68156.1| 553|Homo sapiens RST protein.
Length = 553
Score = 150 bits (363), Expect = 1e-35
Identities = 115/441 (26%), Positives = 188/441 (42%), Gaps = 8/441 (1%)
Query: 100 LTQPCSADTSFSQ-EALAC-DHWIYANN---NTIVAEFNLACQEWK-RTLVGTIHNIGML 153
L P + TS+S+ + C D W+Y + +TIVA++NL C + + +I+ G+L
Sbjct: 98 LLDPNATATSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGIL 157
Query: 154 VSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPAS 213
V G SDRFGR++ L S + V+GT AF+ ++ +Y + FL A A +
Sbjct: 158 VGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNT 217
Query: 214 YILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIY 273
L +E R L + S G A +A + W LVV P L Y +
Sbjct: 218 GTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSW 277
Query: 274 FLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPG 333
+L ES RWLL+ +N M E+ + P
Sbjct: 278 WLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVL--LSAMREELSMGQPPA 335
Query: 334 IWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXI 393
++R P + R I + W F F+GLA++ +L + + M
Sbjct: 336 SLGTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMG 395
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMY 453
L+L +GR+ +L ++ G+ A V + + L L +LG + AF I +Y
Sbjct: 396 ALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIY 455
Query: 454 TSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXX 513
+SELFPT R + + M R G+I+ P + LL ++ WLP +++G +++G
Sbjct: 456 SSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLL 515
Query: 514 XXXXXXXXXXXIQEAEQIATR 534
IQ+ + A +
Sbjct: 516 PETQSLPLPDTIQDVQNQAVK 536
>AB071863-1|BAB96750.1| 553|Homo sapiens URAT1 protein.
Length = 553
Score = 150 bits (363), Expect = 1e-35
Identities = 115/441 (26%), Positives = 188/441 (42%), Gaps = 8/441 (1%)
Query: 100 LTQPCSADTSFSQ-EALAC-DHWIYANN---NTIVAEFNLACQEWK-RTLVGTIHNIGML 153
L P + TS+S+ + C D W+Y + +TIVA++NL C + + +I+ G+L
Sbjct: 98 LLDPNATATSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGIL 157
Query: 154 VSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPAS 213
V G SDRFGR++ L S + V+GT AF+ ++ +Y + FL A A +
Sbjct: 158 VGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNT 217
Query: 214 YILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIY 273
L +E R L + S G A +A + W LVV P L Y +
Sbjct: 218 GTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSW 277
Query: 274 FLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPG 333
+L ES RWLL+ +N M E+ + P
Sbjct: 278 WLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVL--LSAMREELSMGQPPA 335
Query: 334 IWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXI 393
++R P + R I + W F F+GLA++ +L + + M
Sbjct: 336 SLGTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMG 395
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMY 453
L+L +GR+ +L ++ G+ A V + + L L +LG + AF I +Y
Sbjct: 396 ALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIY 455
Query: 454 TSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXX 513
+SELFPT R + + M R G+I+ P + LL ++ WLP +++G +++G
Sbjct: 456 SSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLL 515
Query: 514 XXXXXXXXXXXIQEAEQIATR 534
IQ+ + A +
Sbjct: 516 PETQSLPLPDTIQDVQNQAVK 536
>AL050350-6|CAI42514.1| 432|Homo sapiens solute carrier family 22
(organic cation transporter), member 16 protein.
Length = 432
Score = 149 bits (361), Expect = 2e-35
Identities = 111/432 (25%), Positives = 191/432 (44%), Gaps = 15/432 (3%)
Query: 76 DFNPVWLPNAAVEGQGERCSR-RVPLTQPCSADTSFSQEALAC-DHWIYANN---NTIVA 130
D+ V L N + + RCSR + T + + S++ C D +IY N +T V
Sbjct: 1 DYVTVQLQNGEI-WELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVT 59
Query: 131 EFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
++NL C ++W L+ + G+L+ GY SDR GR+V L + + + + G AF+
Sbjct: 60 QWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFA 119
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK 249
V Y ++ F + + ++ +E +G R + L ++G + AL
Sbjct: 120 VDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGY 179
Query: 250 TFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXX 309
+ W + +++ + F+ + LPE+ WLLS N
Sbjct: 180 LVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKL 239
Query: 310 XXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINS 369
+ E+Q S + + I KR W T + FY ++NS
Sbjct: 240 SELLSLDLQGPVSNSPTEVQKHN--LSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNS 297
Query: 370 VSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFV--RNH 427
V+L G++Y N L + +D++GR R++L + C C + V + H
Sbjct: 298 VNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGR-RTVLAYSLFCSALACGVVMVIPQKH 356
Query: 428 IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAP-QMPL 486
+ L + ++GK AI AF IY+YT+EL+PT R + SMV R+ SI+AP + L
Sbjct: 357 YI-LGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDL 415
Query: 487 LEIYVKWLPSVL 498
I++ ++P +L
Sbjct: 416 SSIWI-FIPQLL 426
>AB026898-2|BAA77625.1| 551|Homo sapiens organic-cation transporter
like 3 protein.
Length = 551
Score = 146 bits (353), Expect = 2e-34
Identities = 126/502 (25%), Positives = 204/502 (40%), Gaps = 28/502 (5%)
Query: 20 RVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECES----LNTT 75
+VL ++G G+F ++ ++F+ P+ C V ++ L+
Sbjct: 6 QVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLSAA 65
Query: 76 DFNPVWLPNAAVEGQGERCSRRVPLTQPCSADTSFSQ---EALACDH-WIYANNN--TIV 129
+ + +P G E C P S S E CD W Y N ++
Sbjct: 66 EQLVLSVP-LDTAGHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRLPSLK 124
Query: 130 AEFNLACQEWKRTLVGTIHNI---GMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLK 186
EFNL C ++ L T ++ G+LV + G + DR GRK ++ L +IG
Sbjct: 125 NEFNLVCD--RKHLKDTTQSVFMGGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLAT 182
Query: 187 AFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFAL 246
AF S+E+Y+ + F A A ++ L E +G R S+G + A
Sbjct: 183 AFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQMVLAG 242
Query: 247 MAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXX 306
+A F+ WR + P LL Y + LPES RWLL+ +N
Sbjct: 243 LAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKL 302
Query: 307 XXXXXXXXXXDKPQTMEEKKEIQNEP-GIWSQVMRSPIIMKRLAICSWWWITCTFVFYGL 365
P+ M + + P G + R P + K I W + +YGL
Sbjct: 303 -----------SPELMNQLVPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGL 351
Query: 366 AINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVR 425
++ D Y ++ + ++ R GRK S L ++ G+ C I F+
Sbjct: 352 SLQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIP 411
Query: 426 NHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMP 485
+ + L ++GK+A AF Y+Y++ELFPT R + + + RIG I+ P +
Sbjct: 412 ADLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVI 471
Query: 486 LLEIYVKWLPSVLFGCTALVAG 507
LL Y LP +++G +VAG
Sbjct: 472 LLGEYHAALPMLIYGSLPIVAG 493
>AB010438-1|BAA76350.1| 551|Homo sapiens organic-cation transporter
like 3 protein.
Length = 551
Score = 146 bits (353), Expect = 2e-34
Identities = 126/502 (25%), Positives = 204/502 (40%), Gaps = 28/502 (5%)
Query: 20 RVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECES----LNTT 75
+VL ++G G+F ++ ++F+ P+ C V ++ L+
Sbjct: 6 QVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLSAA 65
Query: 76 DFNPVWLPNAAVEGQGERCSRRVPLTQPCSADTSFSQ---EALACDH-WIYANNN--TIV 129
+ + +P G E C P S S E CD W Y N ++
Sbjct: 66 EQLVLSVP-LDTAGHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRLPSLK 124
Query: 130 AEFNLACQEWKRTLVGTIHNI---GMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLK 186
EFNL C ++ L T ++ G+LV + G + DR GRK ++ L +IG
Sbjct: 125 NEFNLVCD--RKHLKDTTQSVFMGGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLAT 182
Query: 187 AFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFAL 246
AF S+E+Y+ + F A A ++ L E +G R S+G + A
Sbjct: 183 AFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQMVLAG 242
Query: 247 MAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXX 306
+A F+ WR + P LL Y + LPES RWLL+ +N
Sbjct: 243 LAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKL 302
Query: 307 XXXXXXXXXXDKPQTMEEKKEIQNEP-GIWSQVMRSPIIMKRLAICSWWWITCTFVFYGL 365
P+ M + + P G + R P + K I W + +YGL
Sbjct: 303 -----------SPELMNQLVPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGL 351
Query: 366 AINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVR 425
++ D Y ++ + ++ R GRK S L ++ G+ C I F+
Sbjct: 352 SLQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIP 411
Query: 426 NHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMP 485
+ + L ++GK+A AF Y+Y++ELFPT R + + + RIG I+ P +
Sbjct: 412 ADLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVI 471
Query: 486 LLEIYVKWLPSVLFGCTALVAG 507
LL Y LP +++G +VAG
Sbjct: 472 LLGEYHAALPMLIYGSLPIVAG 493
>AJ271205-1|CAB97249.1| 519|Homo sapiens putative organic anion
transporter protein.
Length = 519
Score = 137 bits (331), Expect = 1e-31
Identities = 107/453 (23%), Positives = 182/453 (40%), Gaps = 14/453 (3%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L Q+G G+F +T F A + C P +L+ V
Sbjct: 6 LLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65
Query: 81 WLPNAAVEGQGERCSR------RVPLTQPCSADTSFSQEALACDHWIYANN---NTIVAE 131
WLP +GQ E C R +P A+ + + E D WIY N+ +TIV E
Sbjct: 66 WLPRDR-QGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCT-DGWIYDNSTFPSTIVTE 123
Query: 132 FNLACQEWK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV 190
++L C R L +++ +G+L+ + GY++DR GR+ LIL+ V GT AF+
Sbjct: 124 WDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAP 183
Query: 191 SYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
++ +Y L +A A L +E + R +G V S+G A +A
Sbjct: 184 NFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYA 243
Query: 251 FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXX 310
+WR L+V P F Y +F ES RW S +N
Sbjct: 244 VPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAK 303
Query: 311 XXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSV 370
+++++ + +++R P + S W +F +YGL ++
Sbjct: 304 LSMEVL--RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQ 361
Query: 371 SLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVW 430
Y ++ + LV++ +GR+ + + ++ G+ +
Sbjct: 362 GFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421
Query: 431 LSIFLYLLGKVAITQAFNGIYMYTSELFPTRAR 463
+ L +LGK + +FN I++YT EL+PT R
Sbjct: 422 VRTSLAVLGKGCLAASFNCIFLYTGELYPTMIR 454
>AJ251529-1|CAB94830.1| 506|Homo sapiens putative organic anion
transporter protein.
Length = 506
Score = 137 bits (331), Expect = 1e-31
Identities = 107/453 (23%), Positives = 182/453 (40%), Gaps = 14/453 (3%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L Q+G G+F +T F A + C P +L+ V
Sbjct: 6 LLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEV 65
Query: 81 WLPNAAVEGQGERCSR------RVPLTQPCSADTSFSQEALACDHWIYANN---NTIVAE 131
WLP +GQ E C R +P A+ + + E D WIY N+ +TIV E
Sbjct: 66 WLPRDR-QGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCT-DGWIYDNSTFPSTIVTE 123
Query: 132 FNLACQEWK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV 190
++L C R L +++ +G+L+ + GY++DR GR+ LIL+ V GT AF+
Sbjct: 124 WDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAP 183
Query: 191 SYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
++ +Y L +A A L +E + R +G V S+G A +A
Sbjct: 184 NFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYA 243
Query: 251 FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXX 310
+WR L+V P F Y +F ES RW S +N
Sbjct: 244 VPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAK 303
Query: 311 XXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSV 370
+++++ + +++R P + S W +F +YGL ++
Sbjct: 304 LSMEVL--RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQ 361
Query: 371 SLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVW 430
Y ++ + LV++ +GR+ + + ++ G+ +
Sbjct: 362 GFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421
Query: 431 LSIFLYLLGKVAITQAFNGIYMYTSELFPTRAR 463
+ L +LGK + +FN I++YT EL+PT R
Sbjct: 422 VRTSLAVLGKGCLAASFNCIFLYTGELYPTMIR 454
>AC002464-1|AAB67044.1| 456|Homo sapiens WUGSC:RG331P03.1 protein.
Length = 456
Score = 135 bits (326), Expect = 4e-31
Identities = 98/393 (24%), Positives = 169/393 (43%), Gaps = 13/393 (3%)
Query: 76 DFNPVWLPNAAVEGQGERCSR-RVPLTQPCSADTSFSQEALAC-DHWIYANN---NTIVA 130
D+ V L N + + RCSR + T + + S++ C D +IY N +T V
Sbjct: 67 DYVTVQLQNGEI-WELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVT 125
Query: 131 EFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
++NL C ++W L+ + G+L+ GY SDR GR+V L + + + + G AF+
Sbjct: 126 QWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFA 185
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK 249
V Y ++ F + + ++ +E +G R + L ++G + AL
Sbjct: 186 VDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGY 245
Query: 250 TFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXX 309
+ W + +++ + F+ + LPE+ WLLS N
Sbjct: 246 LVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKL 305
Query: 310 XXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINS 369
+ E+Q S + + I KR W T + FY ++NS
Sbjct: 306 SELLSLDLQGPVSNSPTEVQKHN--LSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNS 363
Query: 370 VSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFV--RNH 427
V+L G++Y N L + +D++GR R++L + C C + V + H
Sbjct: 364 VNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGR-RTVLAYSLFCSALACGVVMVIPQKH 422
Query: 428 IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPT 460
+ L + ++GK AI AF IY+YT+EL+PT
Sbjct: 423 YI-LGVVTAMVGKFAIGAAFGLIYLYTAELYPT 454
>AB050269-1|BAB68364.1| 552|Homo sapiens organic anion transpoter 4
like protein protein.
Length = 552
Score = 133 bits (322), Expect = 1e-30
Identities = 99/394 (25%), Positives = 163/394 (41%), Gaps = 2/394 (0%)
Query: 141 RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEF 200
+ + +I+ G+LV G SDRFGR++ L S + V+GT AF+ ++ +Y + F
Sbjct: 144 KPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRF 203
Query: 201 LETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILV 260
L A A + L +E R L + S G A +A + W LV
Sbjct: 204 LLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLV 263
Query: 261 VYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQ 320
V P L Y ++L ES RWLL+ +N
Sbjct: 264 VSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVL--LS 321
Query: 321 TMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNY 380
M E+ + P ++R P + R I + W F F+GLA++ +L + +
Sbjct: 322 AMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQ 381
Query: 381 MLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGK 440
M L+L +GR+ +L ++ G+ A V + + L L +LG
Sbjct: 382 MFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGL 441
Query: 441 VAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFG 500
+ AF I +Y+SELFPT R + + M R G+I+ P + LL ++ WLP +++G
Sbjct: 442 GGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYG 501
Query: 501 CTALVAGXXXXXXXXXXXXXXXXXIQEAEQIATR 534
+++G IQ+ + A +
Sbjct: 502 TVPVLSGLAALLLPETQSLPLPDTIQDVQNQAVK 535
>AB209484-1|BAD92721.1| 440|Homo sapiens solute carrier family 22
member 5 variant protein.
Length = 440
Score = 132 bits (320), Expect = 2e-30
Identities = 87/343 (25%), Positives = 163/343 (47%), Gaps = 9/343 (2%)
Query: 165 RFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQD 224
RFGRK L ++ + L+ FS ++EM+V++ L + S + A+++L E+LG+
Sbjct: 49 RFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKS 108
Query: 225 KRVL-TTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLL 283
R++ +T + I + G + L A + WR ++ + P +L ++ +F+PES RWL+
Sbjct: 109 VRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLI 168
Query: 284 SXXXXXXXXXXXXXXXXMNN-VXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSP 342
S N V D ++ I + W+ +R
Sbjct: 169 SQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWN--IRMV 226
Query: 343 IIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIG 402
IM + W+T + ++GL++++ +L GD + N L + L+L +
Sbjct: 227 TIMSIML-----WMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLP 281
Query: 403 RKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRA 462
R+ S+ + G + V + +L+ L ++GK +T AF+ +Y+YT+EL+PT
Sbjct: 282 RRYSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVV 341
Query: 463 RHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALV 505
R+ + S R+GSI++P L Y ++LP +L G ++
Sbjct: 342 RNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTIL 384
>AK057306-1|BAB71419.1| 361|Homo sapiens protein ( Homo sapiens
cDNA FLJ32744 fis, clone TESTI2001420, weakly similar to
D.melanogaster mRNA for putative organic cation
transporter. ).
Length = 361
Score = 129 bits (312), Expect = 2e-29
Identities = 90/359 (25%), Positives = 155/359 (43%), Gaps = 8/359 (2%)
Query: 143 LVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLE 202
L+ + G+L+ GY SDR GR+V L + + + + G AF+V Y ++ F
Sbjct: 2 LIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFL 61
Query: 203 TIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVY 262
+ + ++ +E +G R + L ++G + AL + W + +++
Sbjct: 62 AMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILS 121
Query: 263 PPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTM 322
+ F+ + LPE+ WLLS N +
Sbjct: 122 TVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVS 181
Query: 323 EEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYML 382
E+Q S + + I KR W T + FY ++NSV+L G++Y N L
Sbjct: 182 NSPTEVQKHN--LSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFL 239
Query: 383 XXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFV--RNHIVWLSIFLYLLGK 440
+ D++GR R++L + C C + V + H + L + ++GK
Sbjct: 240 LGVVEIPAYTFVCIATDKVGR-RTVLAYSLFCSALACGVVMVIPQKHYI-LGVVTAMVGK 297
Query: 441 VAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAP-QMPLLEIYVKWLPSVL 498
AI AF IY+YT+EL+PT R + SMV R+ SI+AP + L I++ ++P +L
Sbjct: 298 FAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWI-FIPQLL 355
>AB075951-1|BAC02720.1| 483|Homo sapiens organic cation transporter
hOCT2-A protein.
Length = 483
Score = 126 bits (305), Expect = 2e-28
Identities = 91/325 (28%), Positives = 143/325 (44%), Gaps = 14/325 (4%)
Query: 105 SADTSFSQEALA-C-DHWIYAN-NNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILG 160
S DT+ S+ L C D W+Y ++IV EFNL C W L + N+G + +G
Sbjct: 109 SLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIG 168
Query: 161 YISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIEL 220
YI+DRFGRK+ L+ + + G L A S +Y +I ++ + + + YIL E
Sbjct: 169 YIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEF 228
Query: 221 LGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIR 280
+G+ R F + ++G + A +A +WR V P FL Y + +PES R
Sbjct: 229 VGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPESPR 288
Query: 281 WLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMR 340
WL+S N + +EE+ + P + ++R
Sbjct: 289 WLISQNKNAEAMRIIKHIAKKNGKSLPASL-------QRLRLEEETGKKLNPS-FLDLVR 340
Query: 341 SPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDK-YTNYMLXXXXXXXXXXINALVLD 399
+P I K I + W T + ++ GL I + LAGD Y ++ + L +D
Sbjct: 341 TPQIRKHTMILMYNWFTSSVLYQGL-IMHMGLAGDNIYLDFFYSALVEFPAAFMIILTID 399
Query: 400 RIGRKRSLLIGFMVCGVSCCAIPFV 424
RIGR+ MV G +C A F+
Sbjct: 400 RIGRRYPWAASNMVAGAACLASVFI 424
>AL583834-3|CAI14462.1| 539|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 539
Score = 125 bits (301), Expect = 5e-28
Identities = 115/461 (24%), Positives = 183/461 (39%), Gaps = 16/461 (3%)
Query: 79 PVWLPNAAV--EGQGERCSRRVPLTQPCSADTSFSQEALACDHWIYANNNTIVAEFNLAC 136
P LPN + E Q P T PCS + DH +++ TI E++L C
Sbjct: 86 PQALPNTTLGEERQSRGELEDEPATVPCSQGWEY-------DHSEFSS--TIATEWDLVC 136
Query: 137 -QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY 195
Q+ T G+LV GY+SDRFGR+ L+++ V+G A SVSY M+
Sbjct: 137 EQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 196
Query: 196 VIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWR 255
I L A A L +E L + R + + G + AL+ + WR
Sbjct: 197 AITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWR 256
Query: 256 TFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXX 315
+L V P + ++++PES RWLL+ +N
Sbjct: 257 WLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEA 316
Query: 316 XDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGD 375
K E + P + + R+P + C W F +YGL+++ L +
Sbjct: 317 VSKVAAGER---VVRRPS-YLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLN 372
Query: 376 KYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFL 435
Y +L + L + GR+ + + ++ V + + S L
Sbjct: 373 VYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVL 432
Query: 436 YLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLP 495
++GK AF Y++TSEL+PT R + + ++VGR+G +AP LL+ LP
Sbjct: 433 AVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLP 492
Query: 496 SVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIATRHR 536
+ +G AL+A IQ+ E+ HR
Sbjct: 493 KLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKRCVHR 533
>AF097491-1|AAD19357.1| 568|Homo sapiens organic anion transporter
3 protein.
Length = 568
Score = 125 bits (301), Expect = 5e-28
Identities = 114/491 (23%), Positives = 200/491 (40%), Gaps = 16/491 (3%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L ++G G F + IF A + + C P S
Sbjct: 6 ILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGP------ 59
Query: 81 WLPNAAVEGQGERCSRRV-PLTQPCSADTSFSQEALACDHWIY-ANNNTIVAEFNLACQE 138
W+ G+ ERC R V P DT + E D W+Y + ++IV E++L C
Sbjct: 60 WVLPMGPNGKPERCLRFVHPPNASLPNDTQRAMEP-CLDGWVYNSTKDSIVTEWDLVCNS 118
Query: 139 WK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVI 197
K + + +I G+L+ +LG +SDRFGR + L S L+ G+ AFS ++ +Y++
Sbjct: 119 NKLKEMAQSIFMAGILIGGLVLGDLSDRFGRTI-LTCSYLLLAASGSGAAFSPTFPIYMV 177
Query: 198 VEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTF 257
FL + ++ IL +E + R + + LG + G +A WR
Sbjct: 178 FRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWL 237
Query: 258 ILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXD 317
L V P +F ++ PESIRW + +
Sbjct: 238 QLTVSIPFFVFFLSSWWTPESIRWWSCLEVLEGPEDTPAG----GCLQWQEEGERLSLEE 293
Query: 318 KPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKY 377
++++ + S + R PI + S W F +Y LA+ + Y
Sbjct: 294 LKLNLQKEISLAKAKYTASDLFRIPIGAPHDLLLSLAWFATGFAYYSLAMGVEEFGVNLY 353
Query: 378 TNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYL 437
++ I L L +GR + + A+ FV + + L +
Sbjct: 354 ILQIIFGGVDVPAKFITILSLSYLGRHTTQGRCPAPGRGAILALTFVPLDLQTVETVLAV 413
Query: 438 LGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSV 497
GK ++ +F+ +++YTSEL+PT R + + ++ R+GS+V+P + + ++P++
Sbjct: 414 FGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNI 473
Query: 498 LF-GCTALVAG 507
+F G TAL+ G
Sbjct: 474 IFTGSTALLGG 484
>AF210455-1|AAG43523.1| 539|Homo sapiens organic anion transporter
2 protein.
Length = 539
Score = 124 bits (298), Expect = 1e-27
Identities = 115/461 (24%), Positives = 182/461 (39%), Gaps = 16/461 (3%)
Query: 79 PVWLPNAAV--EGQGERCSRRVPLTQPCSADTSFSQEALACDHWIYANNNTIVAEFNLAC 136
P LPN + E Q P T PCS + DH +++ TI E++L C
Sbjct: 86 PQALPNTTLGEERQSRGELEDEPATVPCSQGWEY-------DHSEFSS--TIATEWDLVC 136
Query: 137 -QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY 195
Q+ T G+LV GY+SDRFGR+ L+++ V+G A SVSY M+
Sbjct: 137 EQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 196
Query: 196 VIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWR 255
I L A A L +E L + R + + G + AL+ + WR
Sbjct: 197 AITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWR 256
Query: 256 TFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXX 315
+L V P + ++++PES RWLL+ N
Sbjct: 257 WLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARPNGRPVCEDSFSQEA 316
Query: 316 XDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGD 375
K E + P + + R+P + C W F +YGL+++ L +
Sbjct: 317 VSKVAAGE---RVVRRPS-YLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLN 372
Query: 376 KYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFL 435
Y +L + L + GR+ + + ++ V + + S L
Sbjct: 373 VYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGAALAFGTRLLVSSDMKSWSTVL 432
Query: 436 YLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLP 495
++GK AF Y++TSEL+PT R + + ++VGR+G +AP LL+ LP
Sbjct: 433 AVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLP 492
Query: 496 SVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQIATRHR 536
+ +G AL+A IQ+ E+ HR
Sbjct: 493 KLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKRCVHR 533
>AL583834-4|CAI14464.1| 546|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 546
Score = 123 bits (296), Expect = 2e-27
Identities = 113/455 (24%), Positives = 181/455 (39%), Gaps = 16/455 (3%)
Query: 79 PVWLPNAAV--EGQGERCSRRVPLTQPCSADTSFSQEALACDHWIYANNNTIVAEFNLAC 136
P LPN + E Q P T PCS + DH +++ TI E++L C
Sbjct: 86 PQALPNTTLGEERQSRGELEDEPATVPCSQGWEY-------DHSEFSS--TIATEWDLVC 136
Query: 137 -QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY 195
Q+ T G+LV GY+SDRFGR+ L+++ V+G A SVSY M+
Sbjct: 137 EQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 196
Query: 196 VIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWR 255
I L A A L +E L + R + + G + AL+ + WR
Sbjct: 197 AITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWR 256
Query: 256 TFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXX 315
+L V P + ++++PES RWLL+ +N
Sbjct: 257 WLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEA 316
Query: 316 XDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGD 375
K E + P + + R+P + C W F +YGL+++ L +
Sbjct: 317 VSKVAAGER---VVRRPS-YLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLN 372
Query: 376 KYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFL 435
Y +L + L + GR+ + + ++ V + + S L
Sbjct: 373 VYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVL 432
Query: 436 YLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLP 495
++GK AF Y++TSEL+PT R + + ++VGR+G +AP LL+ LP
Sbjct: 433 AVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLP 492
Query: 496 SVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQ 530
+ +G AL+A IQ+ E+
Sbjct: 493 KLTYGGIALLAAGTALLLPETRQAQLPETIQDVER 527
>BC035973-1|AAH35973.1| 468|Homo sapiens SLC22A13 protein protein.
Length = 468
Score = 121 bits (292), Expect = 6e-27
Identities = 109/458 (23%), Positives = 180/458 (39%), Gaps = 24/458 (5%)
Query: 20 RVLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECES----LNTT 75
+VL ++G G+F ++ ++F+ P+ C V ++ L+
Sbjct: 6 QVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMILDEPHHCAVAWVKNHTFNLSAA 65
Query: 76 DFNPVWLPNAAVEGQGERCSRRVPLTQPCSADTSFSQ---EALACDH-WIYANNN--TIV 129
+ + +P G E C P S S E CD W Y N ++
Sbjct: 66 EQLVLSVP-LDTAGHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRLPSLK 124
Query: 130 AEFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAF 188
EFNL C ++ + ++ G+LV + G + DR GRK ++ L +IG AF
Sbjct: 125 NEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAF 184
Query: 189 SVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA 248
S+E+Y+ + F A A ++ L E +G R S+G + A +A
Sbjct: 185 VPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQMVLAGLA 244
Query: 249 KTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXX 308
F+ WR + P LL Y + LPES RWLL+ +N
Sbjct: 245 YGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKL-- 302
Query: 309 XXXXXXXXDKPQTMEEKKEIQNEP-GIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAI 367
P+ M + + P G + R P + K I W + +YGL++
Sbjct: 303 ---------SPELMNQLVPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSL 353
Query: 368 NSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNH 427
D Y ++ + ++ R GRK S L ++ G+ C I F+
Sbjct: 354 QVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIPAD 413
Query: 428 IVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHS 465
+ + L ++GK+A AF Y+Y++E FPT R +
Sbjct: 414 LPVVVTMLAVVGKMATAAAFTISYVYSAEFFPTILRQA 451
>BC033805-1|AAH33805.1| 548|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 548
Score = 121 bits (292), Expect = 6e-27
Identities = 110/455 (24%), Positives = 180/455 (39%), Gaps = 14/455 (3%)
Query: 79 PVWLPNAAV--EGQGERCSRRVPLTQPCSADTSFSQEALACDHWIYANNNTIVAEFNLAC 136
P LPN + E Q P T PCS + DH +++ ++++L C
Sbjct: 86 PQALPNTTLGEERQSRGELEDEPATVPCSQGWEY-------DHSEFSSTIATESQWDLVC 138
Query: 137 -QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY 195
Q+ T G+LV GY+SDRFGR+ L+++ V+G A SVSY M+
Sbjct: 139 EQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 198
Query: 196 VIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWR 255
I L A A L +E L + R + + G + AL+ + WR
Sbjct: 199 AITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWR 258
Query: 256 TFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXX 315
+L V P + ++++PES RWLL+ +N
Sbjct: 259 WLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEA 318
Query: 316 XDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGD 375
K E + P + + R+P + C W F +YGL+++ L +
Sbjct: 319 VSKVAAGER---VVRRPS-YLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLN 374
Query: 376 KYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFL 435
Y +L + L + GR+ + + ++ V + + S L
Sbjct: 375 VYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVL 434
Query: 436 YLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLP 495
++GK AF Y++TSEL+PT R + + ++VGR+G +AP LL+ LP
Sbjct: 435 AVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLP 494
Query: 496 SVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQ 530
+ +G AL+A IQ+ E+
Sbjct: 495 KLTYGGIALLAAGTALLLPETRQAQLPETIQDVER 529
>AY050498-1|AAL12496.1| 548|Homo sapiens organic anion transporter
2 protein.
Length = 548
Score = 121 bits (292), Expect = 6e-27
Identities = 110/455 (24%), Positives = 180/455 (39%), Gaps = 14/455 (3%)
Query: 79 PVWLPNAAV--EGQGERCSRRVPLTQPCSADTSFSQEALACDHWIYANNNTIVAEFNLAC 136
P LPN + E Q P T PCS + DH +++ ++++L C
Sbjct: 86 PQALPNTTLGEERQSRGELEDEPATVPCSQGWEY-------DHSEFSSTIATESQWDLVC 138
Query: 137 -QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY 195
Q+ T G+LV GY+SDRFGR+ L+++ V+G A SVSY M+
Sbjct: 139 EQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 198
Query: 196 VIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWR 255
I L A A L +E L + R + + G + AL+ + WR
Sbjct: 199 AITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWR 258
Query: 256 TFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXX 315
+L V P + ++++PES RWLL+ +N
Sbjct: 259 WLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEA 318
Query: 316 XDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGD 375
K E + P + + R+P + C W F +YGL+++ L +
Sbjct: 319 VSKVAAGER---VVRRPS-YLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLN 374
Query: 376 KYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFL 435
Y +L + L + GR+ + + ++ V + + S L
Sbjct: 375 VYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVL 434
Query: 436 YLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLP 495
++GK AF Y++TSEL+PT R + + ++VGR+G +AP LL+ LP
Sbjct: 435 AVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLP 494
Query: 496 SVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQ 530
+ +G AL+A IQ+ E+
Sbjct: 495 KLTYGGIALLAAGTALLLPETRQAQLPETIQDVER 529
>AL583834-5|CAI14463.1| 548|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 548
Score = 121 bits (292), Expect = 6e-27
Identities = 110/455 (24%), Positives = 180/455 (39%), Gaps = 14/455 (3%)
Query: 79 PVWLPNAAV--EGQGERCSRRVPLTQPCSADTSFSQEALACDHWIYANNNTIVAEFNLAC 136
P LPN + E Q P T PCS + DH +++ ++++L C
Sbjct: 86 PQALPNTTLGEERQSRGELEDEPATVPCSQGWEY-------DHSEFSSTIATESQWDLVC 138
Query: 137 -QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY 195
Q+ T G+LV GY+SDRFGR+ L+++ V+G A SVSY M+
Sbjct: 139 EQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 198
Query: 196 VIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWR 255
I L A A L +E L + R + + G + AL+ + WR
Sbjct: 199 AITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWR 258
Query: 256 TFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXX 315
+L V P + ++++PES RWLL+ +N
Sbjct: 259 WLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEA 318
Query: 316 XDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGD 375
K E + P + + R+P + C W F +YGL+++ L +
Sbjct: 319 VSKVAAGER---VVRRPS-YLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLN 374
Query: 376 KYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFL 435
Y +L + L + GR+ + + ++ V + + S L
Sbjct: 375 VYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVL 434
Query: 436 YLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLP 495
++GK AF Y++TSEL+PT R + + ++VGR+G +AP LL+ LP
Sbjct: 435 AVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLP 494
Query: 496 SVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQ 530
+ +G AL+A IQ+ E+
Sbjct: 495 KLTYGGIALLAAGTALLLPETRQAQLPETIQDVER 529
>AF097518-1|AAD37091.1| 548|Homo sapiens liver-specific transporter
protein.
Length = 548
Score = 121 bits (292), Expect = 6e-27
Identities = 110/455 (24%), Positives = 180/455 (39%), Gaps = 14/455 (3%)
Query: 79 PVWLPNAAV--EGQGERCSRRVPLTQPCSADTSFSQEALACDHWIYANNNTIVAEFNLAC 136
P LPN + E Q P T PCS + DH +++ ++++L C
Sbjct: 86 PQALPNTTLGEERQSRGELEDEPATVPCSQGWEY-------DHSEFSSTIATESQWDLVC 138
Query: 137 -QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY 195
Q+ T G+LV GY+SDRFGR+ L+++ V+G A SVSY M+
Sbjct: 139 EQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 198
Query: 196 VIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWR 255
I L A A L +E L + R + + G + AL+ + WR
Sbjct: 199 AITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWR 258
Query: 256 TFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXX 315
+L V P + ++++PES RWLL+ +N
Sbjct: 259 WLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEA 318
Query: 316 XDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGD 375
K E + P + + R+P + C W F +YGL+++ L +
Sbjct: 319 VSKVAAGER---VVRRPS-YLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLN 374
Query: 376 KYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFL 435
Y +L + L + GR+ + + ++ V + + S L
Sbjct: 375 VYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVL 434
Query: 436 YLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLP 495
++GK AF Y++TSEL+PT R + + ++VGR+G +AP LL+ LP
Sbjct: 435 AVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLP 494
Query: 496 SVLFGCTALVAGXXXXXXXXXXXXXXXXXIQEAEQ 530
+ +G AL+A IQ+ E+
Sbjct: 495 KLTYGGIALLAAGTALLLPETRQAQLPETIQDVER 529
>BC034384-1|AAH34384.1| 550|Homo sapiens solute carrier family 22
(organic anion/cation transporter), member 11 protein.
Length = 550
Score = 118 bits (283), Expect = 7e-26
Identities = 100/413 (24%), Positives = 170/413 (41%), Gaps = 9/413 (2%)
Query: 100 LTQPCSADTSFSQ-EALAC-DHWIYANN---NTIVAEFNLACQ-EWKRTLVGTIHNIGML 153
L P + TS+S+ + C D W+Y + +TIVA+++L C + + L +I G+L
Sbjct: 95 LLDPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGIL 154
Query: 154 VSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPAS 213
V I G +S RFGRK L C + V GT F+ ++ +Y + F+ A F +S
Sbjct: 155 VGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSS 214
Query: 214 YILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIY 273
L +E +R +T +G S G +A + WRT L P +
Sbjct: 215 LTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISW 274
Query: 274 FLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPG 333
+LPES RWL+ +N +++E+ EP
Sbjct: 275 WLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLM---SSVKEEVASAKEPR 331
Query: 334 IWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXI 393
+ P++ R + +YGL + SL D + L
Sbjct: 332 SVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRAT 391
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMY 453
AL+L +GR+ + G++ A V + L + +LGK + + +Y
Sbjct: 392 TALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIY 451
Query: 454 TSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVA 506
+ELFPT R + VGR+G+++ P + + + LP +L+G ++ +
Sbjct: 452 KAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIAS 504
>AC044790-3|AAK68155.1| 550|Homo sapiens OAT4 protein.
Length = 550
Score = 118 bits (283), Expect = 7e-26
Identities = 100/413 (24%), Positives = 170/413 (41%), Gaps = 9/413 (2%)
Query: 100 LTQPCSADTSFSQ-EALAC-DHWIYANN---NTIVAEFNLACQ-EWKRTLVGTIHNIGML 153
L P + TS+S+ + C D W+Y + +TIVA+++L C + + L +I G+L
Sbjct: 95 LLDPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGIL 154
Query: 154 VSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPAS 213
V I G +S RFGRK L C + V GT F+ ++ +Y + F+ A F +S
Sbjct: 155 VGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSS 214
Query: 214 YILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIY 273
L +E +R +T +G S G +A + WRT L P +
Sbjct: 215 LTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISW 274
Query: 274 FLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPG 333
+LPES RWL+ +N +++E+ EP
Sbjct: 275 WLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLM---SSVKEEVASAKEPR 331
Query: 334 IWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXI 393
+ P++ R + +YGL + SL D + L
Sbjct: 332 SVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRAT 391
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMY 453
AL+L +GR+ + G++ A V + L + +LGK + + +Y
Sbjct: 392 TALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIY 451
Query: 454 TSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVA 506
+ELFPT R + VGR+G+++ P + + + LP +L+G ++ +
Sbjct: 452 KAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIAS 504
>AB026116-1|BAA95316.1| 550|Homo sapiens organic anion transporter
4 protein.
Length = 550
Score = 118 bits (283), Expect = 7e-26
Identities = 100/413 (24%), Positives = 170/413 (41%), Gaps = 9/413 (2%)
Query: 100 LTQPCSADTSFSQ-EALAC-DHWIYANN---NTIVAEFNLACQ-EWKRTLVGTIHNIGML 153
L P + TS+S+ + C D W+Y + +TIVA+++L C + + L +I G+L
Sbjct: 95 LLDPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGIL 154
Query: 154 VSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPAS 213
V I G +S RFGRK L C + V GT F+ ++ +Y + F+ A F +S
Sbjct: 155 VGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSS 214
Query: 214 YILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIY 273
L +E +R +T +G S G +A + WRT L P +
Sbjct: 215 LTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISW 274
Query: 274 FLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPG 333
+LPES RWL+ +N +++E+ EP
Sbjct: 275 WLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLM---SSVKEEVASAKEPR 331
Query: 334 IWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXI 393
+ P++ R + +YGL + SL D + L
Sbjct: 332 SVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRAT 391
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMY 453
AL+L +GR+ + G++ A V + L + +LGK + + +Y
Sbjct: 392 TALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIY 451
Query: 454 TSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVA 506
+ELFPT R + VGR+G+++ P + + + LP +L+G ++ +
Sbjct: 452 KAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIAS 504
>AK222869-1|BAD96589.1| 550|Homo sapiens solute carrier family 22
member 11 variant protein.
Length = 550
Score = 116 bits (280), Expect = 2e-25
Identities = 100/413 (24%), Positives = 169/413 (40%), Gaps = 9/413 (2%)
Query: 100 LTQPCSADTSFSQ-EALAC-DHWIYANN---NTIVAEFNLACQ-EWKRTLVGTIHNIGML 153
L P + TS+S+ + C D W+Y + +TIVA+++L C + + L +I G+L
Sbjct: 95 LLDPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGIL 154
Query: 154 VSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPAS 213
V I G +S RFGRK L C V GT F+ ++ +Y + F+ A F +S
Sbjct: 155 VGSFIWGLLSYRFGRKPMLSWCCLQSAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSS 214
Query: 214 YILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIY 273
L +E +R +T +G S G +A + WRT L P +
Sbjct: 215 LTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISW 274
Query: 274 FLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPG 333
+LPES RWL+ +N +++E+ EP
Sbjct: 275 WLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLM---SSVKEEVASAKEPR 331
Query: 334 IWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXI 393
+ P++ R + +YGL + SL D + L
Sbjct: 332 SVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRAT 391
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMY 453
AL+L +GR+ + G++ A V + L + +LGK + + +Y
Sbjct: 392 TALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIY 451
Query: 454 TSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVA 506
+ELFPT R + VGR+G+++ P + + + LP +L+G ++ +
Sbjct: 452 KAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIAS 504
>AY437532-1|AAR84082.1| 547|Homo sapiens putative UST1-like organic
anion transporter protein.
Length = 547
Score = 109 bits (263), Expect = 2e-23
Identities = 89/394 (22%), Positives = 159/394 (40%), Gaps = 6/394 (1%)
Query: 118 DHWIYANNN---TIVAEFNLACQEWKRTLVGT-IHNIGMLVSLPILGYISDRFGRKVALI 173
D W+Y ++ TIV +++L C+ V + GM+V + G++SDRFGRK L
Sbjct: 118 DGWVYDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVLR 177
Query: 174 LSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFL 233
S + ++GT AF+ + +Y + FL A S + +L +E + +
Sbjct: 178 WSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTLT 237
Query: 234 GIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXX 293
S+G + +A + LV+ P +F + +L ES RWL+
Sbjct: 238 LCAASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLK 297
Query: 294 XXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSW 353
N + TM+++ E + +++R P I KR+ S+
Sbjct: 298 ELRKAAHRNGMKNAEDILTMEVL--KSTMKQELEAAQKKHSLCELLRIPNICKRICFLSF 355
Query: 354 WWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMV 413
T F+GL ++ L + + L + L+ + R+ S ++ +
Sbjct: 356 VRFASTIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAPWALNHMSRRLSQMLLMFL 415
Query: 414 CGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMV 473
AI FV + L + L LG A + +EL P+ R
Sbjct: 416 LATCLLAIIFVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIPSIIRGRATGITGNF 475
Query: 474 GRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
IG +A + +L IY + LP +++G A+++G
Sbjct: 476 ANIGGALASLVMILSIYSRPLPWIIYGVFAILSG 509
>BC101316-1|AAI01317.1| 547|Homo sapiens LOC387601 protein protein.
Length = 547
Score = 109 bits (262), Expect = 2e-23
Identities = 89/394 (22%), Positives = 159/394 (40%), Gaps = 6/394 (1%)
Query: 118 DHWIYANNN---TIVAEFNLACQEWKRTLVGT-IHNIGMLVSLPILGYISDRFGRKVALI 173
D W+Y ++ TIV +++L C+ V + GM+V + G++SDRFGRK L
Sbjct: 118 DGWVYDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVLR 177
Query: 174 LSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFL 233
S + ++GT AF+ + +Y + FL A S + +L +E + +
Sbjct: 178 WSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTLT 237
Query: 234 GIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXX 293
S+G + +A + LV+ P +F + +L ES RWL+
Sbjct: 238 LCAASIGHITLGGLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLK 297
Query: 294 XXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSW 353
N + TM+++ E + +++R P I KR+ S+
Sbjct: 298 ELTKAAHRNGMKNAEDILTMEVLKS--TMKQELEAAQKKHSLCELLRIPNICKRICFLSF 355
Query: 354 WWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMV 413
T F+GL ++ L + + L + L+ + R+ S ++ +
Sbjct: 356 VRFASTIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAPWALNHMSRRLSQMLLMFL 415
Query: 414 CGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMV 473
AI FV + L + L LG A + +EL P+ R
Sbjct: 416 LATCLLAIIFVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIPSIIRGRATGITGNF 475
Query: 474 GRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
IG +A + +L IY + LP +++G A+++G
Sbjct: 476 ANIGGALASLVMILSIYSRPLPWIIYGVFAILSG 509
>AK075224-1|BAC11483.1| 401|Homo sapiens protein ( Homo sapiens
cDNA FLJ90743 fis, clone PLACE1011236, weakly similar to
Mus musculus mRNA for RST. ).
Length = 401
Score = 102 bits (245), Expect = 3e-21
Identities = 83/356 (23%), Positives = 140/356 (39%), Gaps = 3/356 (0%)
Query: 151 GMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTF 210
G+LV I G +S RFGRK L C + V GT F+ ++ +Y + F+ A F
Sbjct: 3 GILVGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIF 62
Query: 211 PASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLS 270
+S L +E +R +T +G S G +A + WRT L P
Sbjct: 63 LSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISL 122
Query: 271 YIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQN 330
++LPES RWL+ +N +++E+
Sbjct: 123 ISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLM---SSVKEEVASAK 179
Query: 331 EPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXX 390
EP + P++ R + +YGL + SL D + L
Sbjct: 180 EPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFRLQALFGAVDFLG 239
Query: 391 XXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGI 450
AL+L +GR+ + G++ A V + L + +LGK + +
Sbjct: 240 RATTALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCL 299
Query: 451 YMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVA 506
+Y +ELFPT R + VGR+G+++ P + + + LP +L+G ++ +
Sbjct: 300 TIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIAS 355
>AL162582-2|CAI20004.1| 334|Homo sapiens solute carrier family 22
(organic cation transporter), member 2 protein.
Length = 334
Score = 102 bits (244), Expect = 4e-21
Identities = 60/184 (32%), Positives = 92/184 (50%), Gaps = 4/184 (2%)
Query: 105 SADTSFSQEALA-C-DHWIYAN-NNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILG 160
S DT+ S+ L C D W+Y ++IV EFNL C W L + N+G + +G
Sbjct: 88 SLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIG 147
Query: 161 YISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIEL 220
YI+DRFGRK+ L+ + + G L A S +Y +I ++ + + + YIL E
Sbjct: 148 YIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEF 207
Query: 221 LGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIR 280
+G+ R F + ++G + A +A +WR V P FL Y + +PES R
Sbjct: 208 VGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPR 267
Query: 281 WLLS 284
WL+S
Sbjct: 268 WLIS 271
>BC126288-1|AAI26289.1| 553|Homo sapiens solute carrier family 22
(organic anion/cation transporter), member 9 protein.
Length = 553
Score = 100 bits (240), Expect = 1e-20
Identities = 97/441 (21%), Positives = 171/441 (38%), Gaps = 15/441 (3%)
Query: 107 DTSFSQEALACDHWIYAN---NNTIVAEFNLACQEWKRTLVGT-IHNIGMLVSLPILGYI 162
+TS + D W+Y ++TIV E++L C T V + GM+V + G++
Sbjct: 107 NTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHL 166
Query: 163 SDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLG 222
SDRFGR+ L V ++GT A + ++ +Y + FL IA S + +L E
Sbjct: 167 SDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWAT 226
Query: 223 QDKRVLTTAFLGIVISM--GGVCF---ALMAKTFQYWRTFILVVYPPALLFLSYIYFLPE 277
+ + GI + M G+ F A +A + W LVV P + +L E
Sbjct: 227 HRFQAM-----GITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLE 281
Query: 278 SIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQ 337
S RWL+ + + E + + +P + +
Sbjct: 282 SARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSL-CE 340
Query: 338 VMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALV 397
++ P I KR+++ S+ ++GL ++ L + + L +
Sbjct: 341 MLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWA 400
Query: 398 LDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSEL 457
L + R+ S ++ + + AI FV + L L LG A A + + +E+
Sbjct: 401 LKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEV 460
Query: 458 FPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXX 517
PT R + + I +AP M +L +Y LP +++G ++G
Sbjct: 461 IPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETR 520
Query: 518 XXXXXXXIQEAEQIATRHREP 538
IQ+ + REP
Sbjct: 521 NKPLFDTIQDEKNERKDPREP 541
>AJ295270-1|CAC82910.1| 553|Homo sapiens putative integral membrane
transport protein protein.
Length = 553
Score = 100 bits (240), Expect = 1e-20
Identities = 97/441 (21%), Positives = 171/441 (38%), Gaps = 15/441 (3%)
Query: 107 DTSFSQEALACDHWIYAN---NNTIVAEFNLACQEWKRTLVGT-IHNIGMLVSLPILGYI 162
+TS + D W+Y ++TIV E++L C T V + GM+V + G++
Sbjct: 107 NTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHL 166
Query: 163 SDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLG 222
SDRFGR+ L V ++GT A + ++ +Y + FL IA S + +L E
Sbjct: 167 SDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWAT 226
Query: 223 QDKRVLTTAFLGIVISM--GGVCF---ALMAKTFQYWRTFILVVYPPALLFLSYIYFLPE 277
+ + GI + M G+ F A +A + W LVV P + +L E
Sbjct: 227 HRFQAM-----GITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLE 281
Query: 278 SIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQ 337
S RWL+ + + E + + +P + +
Sbjct: 282 SARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSL-CE 340
Query: 338 VMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALV 397
++ P I KR+++ S+ ++GL ++ L + + L +
Sbjct: 341 MLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWA 400
Query: 398 LDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSEL 457
L + R+ S ++ + + AI FV + L L LG A A + + +E+
Sbjct: 401 LKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEV 460
Query: 458 FPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXX 517
PT R + + I +AP M +L +Y LP +++G ++G
Sbjct: 461 IPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETR 520
Query: 518 XXXXXXXIQEAEQIATRHREP 538
IQ+ + REP
Sbjct: 521 NKPLFDTIQDEKNERKDPREP 541
>AF440402-1|AAP97316.1| 553|Homo sapiens putative integral membrane
transport protein protein.
Length = 553
Score = 100 bits (240), Expect = 1e-20
Identities = 97/441 (21%), Positives = 171/441 (38%), Gaps = 15/441 (3%)
Query: 107 DTSFSQEALACDHWIYAN---NNTIVAEFNLACQEWKRTLVGT-IHNIGMLVSLPILGYI 162
+TS + D W+Y ++TIV E++L C T V + GM+V + G++
Sbjct: 107 NTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHL 166
Query: 163 SDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLG 222
SDRFGR+ L V ++GT A + ++ +Y + FL IA S + +L E
Sbjct: 167 SDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWAT 226
Query: 223 QDKRVLTTAFLGIVISM--GGVCF---ALMAKTFQYWRTFILVVYPPALLFLSYIYFLPE 277
+ + GI + M G+ F A +A + W LVV P + +L E
Sbjct: 227 HRFQAM-----GITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLE 281
Query: 278 SIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQ 337
S RWL+ + + E + + +P + +
Sbjct: 282 SARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSL-CE 340
Query: 338 VMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALV 397
++ P I KR+++ S+ ++GL ++ L + + L +
Sbjct: 341 MLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWA 400
Query: 398 LDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSEL 457
L + R+ S ++ + + AI FV + L L LG A A + + +E+
Sbjct: 401 LKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEV 460
Query: 458 FPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXX 517
PT R + + I +AP M +L +Y LP +++G ++G
Sbjct: 461 IPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETR 520
Query: 518 XXXXXXXIQEAEQIATRHREP 538
IQ+ + REP
Sbjct: 521 NKPLFDTIQDEKNERKDPREP 541
>AB074812-1|BAF51552.1| 553|Homo sapiens organic anion transporter
7 protein.
Length = 553
Score = 100 bits (240), Expect = 1e-20
Identities = 97/441 (21%), Positives = 171/441 (38%), Gaps = 15/441 (3%)
Query: 107 DTSFSQEALACDHWIYAN---NNTIVAEFNLACQEWKRTLVGT-IHNIGMLVSLPILGYI 162
+TS + D W+Y ++TIV E++L C T V + GM+V + G++
Sbjct: 107 NTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHL 166
Query: 163 SDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLG 222
SDRFGR+ L V ++GT A + ++ +Y + FL IA S + +L E
Sbjct: 167 SDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWAT 226
Query: 223 QDKRVLTTAFLGIVISM--GGVCF---ALMAKTFQYWRTFILVVYPPALLFLSYIYFLPE 277
+ + GI + M G+ F A +A + W LVV P + +L E
Sbjct: 227 HRFQAM-----GITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLE 281
Query: 278 SIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQ 337
S RWL+ + + E + + +P + +
Sbjct: 282 SARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSL-CE 340
Query: 338 VMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALV 397
++ P I KR+++ S+ ++GL ++ L + + L +
Sbjct: 341 MLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWA 400
Query: 398 LDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSEL 457
L + R+ S ++ + + AI FV + L L LG A A + + +E+
Sbjct: 401 LKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEV 460
Query: 458 FPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXX 517
PT R + + I +AP M +L +Y LP +++G ++G
Sbjct: 461 IPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETR 520
Query: 518 XXXXXXXIQEAEQIATRHREP 538
IQ+ + REP
Sbjct: 521 NKPLFDTIQDEKNERKDPREP 541
>AB062418-1|BAB83517.1| 553|Homo sapiens hUST3 protein.
Length = 553
Score = 100 bits (240), Expect = 1e-20
Identities = 97/441 (21%), Positives = 171/441 (38%), Gaps = 15/441 (3%)
Query: 107 DTSFSQEALACDHWIYAN---NNTIVAEFNLACQEWKRTLVGT-IHNIGMLVSLPILGYI 162
+TS + D W+Y ++TIV E++L C T V + GM+V + G++
Sbjct: 107 NTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHL 166
Query: 163 SDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLG 222
SDRFGR+ L V ++GT A + ++ +Y + FL IA S + +L E
Sbjct: 167 SDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWAT 226
Query: 223 QDKRVLTTAFLGIVISM--GGVCF---ALMAKTFQYWRTFILVVYPPALLFLSYIYFLPE 277
+ + GI + M G+ F A +A + W LVV P + +L E
Sbjct: 227 HRFQAM-----GITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLE 281
Query: 278 SIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQ 337
S RWL+ + + E + + +P + +
Sbjct: 282 SARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSL-CE 340
Query: 338 VMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALV 397
++ P I KR+++ S+ ++GL ++ L + + L +
Sbjct: 341 MLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWA 400
Query: 398 LDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSEL 457
L + R+ S ++ + + AI FV + L L LG A A + + +E+
Sbjct: 401 LKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEV 460
Query: 458 FPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXX 517
PT R + + I +AP M +L +Y LP +++G ++G
Sbjct: 461 IPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPGTR 520
Query: 518 XXXXXXXIQEAEQIATRHREP 538
IQ+ + REP
Sbjct: 521 NKPLFDTIQDEKNERKDPREP 541
>AK074246-1|BAB85030.1| 552|Homo sapiens protein ( Homo sapiens
cDNA FLJ23666 fis, clone HEP04439. ).
Length = 552
Score = 99.5 bits (237), Expect = 3e-20
Identities = 92/410 (22%), Positives = 164/410 (40%), Gaps = 15/410 (3%)
Query: 107 DTSFSQEALACDHWIYAN---NNTIVAEFNLACQEWKRTLVGT-IHNIGMLVSLPILGYI 162
+TS + D W+Y ++TIV E++L C T V + GM+V + G++
Sbjct: 107 NTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHL 166
Query: 163 SDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLG 222
SDRFGR+ L V ++GT A + ++ +Y + FL IA S + +L E
Sbjct: 167 SDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWAT 226
Query: 223 QDKRVLTTAFLGIVISM--GGVCF---ALMAKTFQYWRTFILVVYPPALLFLSYIYFLPE 277
+ + GI + M G+ F A +A + W LVV P + +L E
Sbjct: 227 HRFQAM-----GITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLE 281
Query: 278 SIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQ 337
S RWL+ + + E + + +P + +
Sbjct: 282 SARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSL-CE 340
Query: 338 VMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALV 397
++ P I KR+++ S+ ++GL ++ L + + L +
Sbjct: 341 MLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWA 400
Query: 398 LDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSEL 457
L + R+ S ++ + + AI FV + L L LG A A + + +E+
Sbjct: 401 LKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEV 460
Query: 458 FPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
PT R + + I +AP M +L +Y LP +++G ++G
Sbjct: 461 IPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISG 510
>AK129930-1|BAC85252.1| 442|Homo sapiens er 11 (SLC22A11).
protein.
Length = 442
Score = 86.6 bits (205), Expect = 2e-16
Identities = 59/190 (31%), Positives = 91/190 (47%), Gaps = 6/190 (3%)
Query: 100 LTQPCSADTSFSQ-EALAC-DHWIYANN---NTIVAEFNLACQ-EWKRTLVGTIHNIGML 153
L P + TS+S+ + C D W+Y + +TIVA+++L C + + L +I G+L
Sbjct: 95 LLDPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGIL 154
Query: 154 VSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPAS 213
V I G +S RFGRK L C + V GT F+ ++ +Y + F+ A F +S
Sbjct: 155 VGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSS 214
Query: 214 YILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIY 273
L +E +R +T +G S G +A + WRT L P +
Sbjct: 215 LTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISW 274
Query: 274 FLPESIRWLL 283
+LPES RWL+
Sbjct: 275 WLPESARWLI 284
>AY358183-1|AAQ88550.1| 445|Homo sapiens SLC22A12 protein.
Length = 445
Score = 83.4 bits (197), Expect = 2e-15
Identities = 61/261 (23%), Positives = 105/261 (40%), Gaps = 2/261 (0%)
Query: 274 FLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPG 333
+L ES RWLL+ +N M E+ + P
Sbjct: 170 WLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVL--LSAMREELSMGQPPA 227
Query: 334 IWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXI 393
++R P + R I + W F F+GLA++ +L + + M
Sbjct: 228 SLGTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMG 287
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMY 453
L+L +GR+ +L ++ G+ A V + + L L +LG + AF I +Y
Sbjct: 288 ALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTYITIY 347
Query: 454 TSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXX 513
+SELFPT R + + M R G+I+ P + LL ++ WLP +++G +++G
Sbjct: 348 SSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLL 407
Query: 514 XXXXXXXXXXXIQEAEQIATR 534
IQ+ + A +
Sbjct: 408 PETQSLPLPDTIQDVQNQAVK 428
>BC126482-1|AAI26483.1| 594|Homo sapiens solute carrier family 22
(organic cation transporter), member 14 protein.
Length = 594
Score = 81.8 bits (193), Expect = 6e-15
Identities = 92/447 (20%), Positives = 176/447 (39%), Gaps = 30/447 (6%)
Query: 118 DHWIY--ANNNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D WIY A +++ EF+L C E K+ + G+ + I I+D+ GR A++L
Sbjct: 157 DGWIYPDAKKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILL 216
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
S + + G AF S+ +Y+ F + + +S L E L + R
Sbjct: 217 SLLGLIIFGFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGH 276
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
++G + +A +W+ LV + F+SYI+ LPES RWL+
Sbjct: 277 CFFAVGAMLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQV 336
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
+N D+ Q +K++ + ++ + K + S
Sbjct: 337 LCYAASVNK-----KTIPSNLLDELQL--PRKKVTRASVL--DFCKNRQLCKVTLVMSCV 387
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T ++ ++ L++ L + +++ +L +IGRK SL + +
Sbjct: 388 WFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQA 447
Query: 415 GVSCCAIPFVRN-----HIVW----------LSIFLYLLGKVAITQAFNGIYMYTSELFP 459
+ C + F+ + W ++I + +L + ++ ++YT+EL P
Sbjct: 448 IIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLP 507
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXX 519
T R + L S+ G+I++ + ++ LP L A+VA
Sbjct: 508 TVLRATGLGLVSLASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLRETRDQ 565
Query: 520 XXXXXIQEAEQIATRHREPHKSKEIQS 546
+ + QI + ++ K+KE S
Sbjct: 566 PLSESLNHSSQIRNKVKD-MKTKETSS 591
>BC130543-1|AAI30544.1| 594|Homo sapiens solute carrier family 22
(organic cation transporter), member 14 protein.
Length = 594
Score = 81.4 bits (192), Expect = 7e-15
Identities = 92/447 (20%), Positives = 176/447 (39%), Gaps = 30/447 (6%)
Query: 118 DHWIY--ANNNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D WIY A +++ EF+L C E K+ + G+ + I I+D+ GR A++L
Sbjct: 157 DGWIYPDAKKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILL 216
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
S + + G AF S+ +Y+ F + + +S L E L + R
Sbjct: 217 SLLGLIIFGFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGH 276
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
++G + +A +W+ LV + F+SYI+ LPES RWL+
Sbjct: 277 CFFAVGAMLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQV 336
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
+N D+ Q +K++ + ++ + K + S
Sbjct: 337 LCYAASVNK-----KTIPSNLLDELQL--PRKKVTRASVL--DFCKNRQLCKVTLVMSCV 387
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T ++ ++ L++ L + +++ +L +IGRK SL + +
Sbjct: 388 WFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQA 447
Query: 415 GVSCCAIPFVRN-----HIVW----------LSIFLYLLGKVAITQAFNGIYMYTSELFP 459
+ C + F+ + W ++I + +L + ++ ++YT+EL P
Sbjct: 448 IIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLP 507
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXX 519
T R + L S+ G+I++ + ++ LP L A+VA
Sbjct: 508 TVLRATGLGLVSLASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLPETRDQ 565
Query: 520 XXXXXIQEAEQIATRHREPHKSKEIQS 546
+ + QI + ++ K+KE S
Sbjct: 566 PLSESLNHSSQIRNKVKD-MKTKETSS 591
>BC075071-1|AAH75071.1| 594|Homo sapiens solute carrier family 22
(organic cation transporter), member 14 protein.
Length = 594
Score = 81.4 bits (192), Expect = 7e-15
Identities = 92/447 (20%), Positives = 176/447 (39%), Gaps = 30/447 (6%)
Query: 118 DHWIY--ANNNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D WIY A +++ EF+L C E K+ + G+ + I I+D+ GR A++L
Sbjct: 157 DGWIYPDAKKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILL 216
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
S + + G AF S+ +Y+ F + + +S L E L + R
Sbjct: 217 SLLGLIIFGFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGH 276
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
++G + +A +W+ LV + F+SYI+ LPES RWL+
Sbjct: 277 CFFAVGAMLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQV 336
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
+N D+ Q +K++ + ++ + K + S
Sbjct: 337 LCYAASVNK-----KTIPSNLLDELQL--PRKKVTRASVL--DFCKNRQLCKVTLVMSCV 387
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T ++ ++ L++ L + +++ +L +IGRK SL + +
Sbjct: 388 WFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQA 447
Query: 415 GVSCCAIPFVRN-----HIVW----------LSIFLYLLGKVAITQAFNGIYMYTSELFP 459
+ C + F+ + W ++I + +L + ++ ++YT+EL P
Sbjct: 448 IIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLP 507
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXX 519
T R + L S+ G+I++ + ++ LP L A+VA
Sbjct: 508 TVLRATGLGLVSLASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLPETRDQ 565
Query: 520 XXXXXIQEAEQIATRHREPHKSKEIQS 546
+ + QI + ++ K+KE S
Sbjct: 566 PLSESLNHSSQIRNKVKD-MKTKETSS 591
>BC075070-1|AAH75070.1| 594|Homo sapiens solute carrier family 22
(organic cation transporter), member 14 protein.
Length = 594
Score = 81.4 bits (192), Expect = 7e-15
Identities = 92/447 (20%), Positives = 176/447 (39%), Gaps = 30/447 (6%)
Query: 118 DHWIY--ANNNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D WIY A +++ EF+L C E K+ + G+ + I I+D+ GR A++L
Sbjct: 157 DGWIYPDAKKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILL 216
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
S + + G AF S+ +Y+ F + + +S L E L + R
Sbjct: 217 SLLGLIIFGFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGH 276
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
++G + +A +W+ LV + F+SYI+ LPES RWL+
Sbjct: 277 CFFAVGAMLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQV 336
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
+N D+ Q +K++ + ++ + K + S
Sbjct: 337 LCYAASVNK-----KTIPSNLLDELQL--PRKKVTRASVL--DFCKNRQLCKVTLVMSCV 387
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T ++ ++ L++ L + +++ +L +IGRK SL + +
Sbjct: 388 WFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQA 447
Query: 415 GVSCCAIPFVRN-----HIVW----------LSIFLYLLGKVAITQAFNGIYMYTSELFP 459
+ C + F+ + W ++I + +L + ++ ++YT+EL P
Sbjct: 448 IIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLP 507
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXX 519
T R + L S+ G+I++ + ++ LP L A+VA
Sbjct: 508 TVLRATGLGLVSLASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLPETRDQ 565
Query: 520 XXXXXIQEAEQIATRHREPHKSKEIQS 546
+ + QI + ++ K+KE S
Sbjct: 566 PLSESLNHSSQIRNKVKD-MKTKETSS 591
>AK128610-1|BAC87527.1| 221|Homo sapiens . protein.
Length = 221
Score = 80.2 bits (189), Expect = 2e-14
Identities = 43/163 (26%), Positives = 86/163 (52%)
Query: 343 IIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIG 402
I++ +L+ + +T + ++GL++++ +L GD + N L + L+L +
Sbjct: 3 ILLFQLSSALCFRMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLP 62
Query: 403 RKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPTRA 462
R+ S+ + G + V + +L+ L ++GK +T AF+ +Y+YT+EL+PT
Sbjct: 63 RRYSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVV 122
Query: 463 RHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALV 505
R+ + S R+GSI++P L Y ++LP +L G ++
Sbjct: 123 RNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTIL 165
>AB026898-3|BAA77626.1| 594|Homo sapiens organic-cation transporter
like 4 protein.
Length = 594
Score = 78.2 bits (184), Expect = 7e-14
Identities = 91/447 (20%), Positives = 175/447 (39%), Gaps = 30/447 (6%)
Query: 118 DHWIY--ANNNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D WIY A +++ EF+L C E K+ + G+ + I I+D+ GR A++L
Sbjct: 157 DGWIYPDAKKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILL 216
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
S + + G AF S+ +Y+ F + + +S L E L + R
Sbjct: 217 SLLGLIIFGFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGH 276
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
++ + +A +W+ LV + F+SYI+ LPES RWL+
Sbjct: 277 CFFAVWAMLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQV 336
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
+N D+ Q +K++ + ++ + K + S
Sbjct: 337 LCYAASVNK-----KTIPSNLLDELQL--PRKKVTRASVL--DFCKNRQLCKVTLVMSCV 387
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T ++ ++ L++ L + +++ +L +IGRK SL + +
Sbjct: 388 WFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQA 447
Query: 415 GVSCCAIPFVRN-----HIVW----------LSIFLYLLGKVAITQAFNGIYMYTSELFP 459
+ C + F+ + W ++I + +L + ++ ++YT+EL P
Sbjct: 448 IIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLP 507
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXX 519
T R + L S+ G+I++ + ++ LP L A+VA
Sbjct: 508 TVLRATGLGLVSLASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLPETRDQ 565
Query: 520 XXXXXIQEAEQIATRHREPHKSKEIQS 546
+ + QI + ++ K+KE S
Sbjct: 566 PLSESLNHSSQIRNKVKD-MKTKETSS 591
>AB011082-1|BAA76351.1| 594|Homo sapiens organic-cation transporter
like 4 protein.
Length = 594
Score = 78.2 bits (184), Expect = 7e-14
Identities = 91/447 (20%), Positives = 175/447 (39%), Gaps = 30/447 (6%)
Query: 118 DHWIY--ANNNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALIL 174
D WIY A +++ EF+L C E K+ + G+ + I I+D+ GR A++L
Sbjct: 157 DGWIYPDAKKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILL 216
Query: 175 SCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLG 234
S + + G AF S+ +Y+ F + + +S L E L + R
Sbjct: 217 SLLGLIIFGFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGH 276
Query: 235 IVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXX 294
++ + +A +W+ LV + F+SYI+ LPES RWL+
Sbjct: 277 CFFAVWAMLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQV 336
Query: 295 XXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWW 354
+N D+ Q +K++ + ++ + K + S
Sbjct: 337 LCYAASVNK-----KTIPSNLLDELQL--PRKKVTRASVL--DFCKNRQLCKVTLVMSCV 387
Query: 355 WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVC 414
W T ++ ++ L++ L + +++ +L +IGRK SL + +
Sbjct: 388 WFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQA 447
Query: 415 GVSCCAIPFVRN-----HIVW----------LSIFLYLLGKVAITQAFNGIYMYTSELFP 459
+ C + F+ + W ++I + +L + ++ ++YT+EL P
Sbjct: 448 IIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLP 507
Query: 460 TRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAGXXXXXXXXXXXX 519
T R + L S+ G+I++ + ++ LP L A+VA
Sbjct: 508 TVLRATGLGLVSLASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLPETRDQ 565
Query: 520 XXXXXIQEAEQIATRHREPHKSKEIQS 546
+ + QI + ++ K+KE S
Sbjct: 566 PLSESLNHSSQIRNKVKD-MKTKETSS 591
>BC101315-1|AAI01316.1| 398|Homo sapiens LOC387601 protein protein.
Length = 398
Score = 71.7 bits (168), Expect = 6e-12
Identities = 56/240 (23%), Positives = 99/240 (41%), Gaps = 6/240 (2%)
Query: 118 DHWIYANNN---TIVAEFNLACQEWKRTLVGT-IHNIGMLVSLPILGYISDRFGRKVALI 173
D W+Y ++ TIV +++L C+ V + GM+V + G++SDRFGRK L
Sbjct: 116 DGWVYDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVLR 175
Query: 174 LSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFL 233
S + ++GT AF+ + +Y + FL A S + +L +E + +
Sbjct: 176 WSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTLT 235
Query: 234 GIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXX 293
S+G + +A + LV+ P +F + +L ES RWL+
Sbjct: 236 LCAASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLK 295
Query: 294 XXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSW 353
N + TM+++ E + +++R P I KR+ S+
Sbjct: 296 ELRKAAHRNGMKNAEDILTMEVL--KSTMKQELEAAQKKHSLCELLRIPNICKRICFLSF 353
>AB075876-1|BAD38658.1| 269|Homo sapiens putative protein product
of HMFN2567 protein.
Length = 269
Score = 69.3 bits (162), Expect = 3e-11
Identities = 49/217 (22%), Positives = 86/217 (39%), Gaps = 2/217 (0%)
Query: 152 MLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFP 211
MLV I G++SDRFGR+ L + + T AF+ ++ +Y ++ FL +
Sbjct: 1 MLVGGIIGGHVSDRFGRRFILRWCLLQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIIS 60
Query: 212 ASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSY 271
+ + E + + + L +S+G + +A F+ W+T +V P +F
Sbjct: 61 NNSLPITEWIRPNSKALVVILSSGALSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLL 120
Query: 272 IYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNE 331
+L ES RWL+ N + TM+E+ +
Sbjct: 121 SRWLVESARWLIITNKLDEGLKALRKVARTNGIKNAEETLNIEVV--RSTMQEELDAAQT 178
Query: 332 PGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAIN 368
+ R+P + KR+ I + T FYG +N
Sbjct: 179 KTTVCDLFRNPSMRKRICILVFLRFANTIPFYGTMVN 215
>BC034394-1|AAH34394.1| 322|Homo sapiens hypothetical protein
MGC34821 protein.
Length = 322
Score = 68.5 bits (160), Expect = 6e-11
Identities = 47/161 (29%), Positives = 80/161 (49%), Gaps = 5/161 (3%)
Query: 118 DHWIYANNN---TIVAEFNLACQEWK-RTLVGTIHNIGMLVSLPILGYISDRFGRKVALI 173
D W+Y ++ TIV E++L C+ +++V ++ G L+ I G++SDR GRK+
Sbjct: 118 DGWVYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICK 177
Query: 174 LSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFL 233
L + + T AF+ ++ +Y I+ FL + + ++IL++E R +T L
Sbjct: 178 LCFLQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVL 237
Query: 234 GIVISMGGVCFALMAKTFQYWRTFILVVYPPAL-LFLSYIY 273
S+G + +A Q W L V P + LFLS Y
Sbjct: 238 LCSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWY 278
>BC030978-1|AAH30978.1| 242|Homo sapiens SLC22A2 protein protein.
Length = 242
Score = 67.3 bits (157), Expect = 1e-10
Identities = 39/117 (33%), Positives = 61/117 (52%), Gaps = 4/117 (3%)
Query: 105 SADTSFSQEALA-C-DHWIYAN-NNTIVAEFNLAC-QEWKRTLVGTIHNIGMLVSLPILG 160
S DT+ S+ L C D W+Y ++IV EFNL C W L + N+G + +G
Sbjct: 109 SLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIG 168
Query: 161 YISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILT 217
YI+DRFGRK+ L+ + + G L A S +Y +I ++ + + + YIL+
Sbjct: 169 YIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILS 225
>BC026291-1|AAH26291.1| 440|Homo sapiens Unknown (protein for
IMAGE:4608353) protein.
Length = 440
Score = 66.9 bits (156), Expect = 2e-10
Identities = 61/216 (28%), Positives = 93/216 (43%), Gaps = 31/216 (14%)
Query: 100 LTQPCSADTSFSQ-EALAC-DHWIYANN---NTIVAEFNLACQEWK-RTLVGTIHNIGML 153
L P + TS+S+ + C D W+Y + +TIVA++NL C + + +I+ G+L
Sbjct: 98 LLDPNATATSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGIL 157
Query: 154 VSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETI--------- 204
V G SDRFGR++ L S + V+GT AF+ ++ +Y + FL
Sbjct: 158 VGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNT 217
Query: 205 ----------------AGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA 248
AG+ P + +E R L + S G A +A
Sbjct: 218 GTLRRSLTWRHAGGLHAGSRAEPLGLLAVMEWTAARARPLVMTLNSLGFSFGHGLTAAVA 277
Query: 249 KTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLS 284
+ W LVV P L Y ++L ES RWLL+
Sbjct: 278 YGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLT 313
>CR457086-1|CAG33367.1| 683|Homo sapiens SV2B protein.
Length = 683
Score = 66.5 bits (155), Expect = 2e-10
Identities = 58/239 (24%), Positives = 97/239 (40%), Gaps = 20/239 (8%)
Query: 130 AEFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
AE ++ K+ ++G I +GM+ ILG ++D+ GRK L +S + +L +F
Sbjct: 136 AEKDMCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFV 195
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK 249
Y ++ + I P + E L ++KR ++LGI GG+ + MA
Sbjct: 196 QGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAW 255
Query: 250 T----------------FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXX-- 291
+ F WR F++V P + + + F+PES R+LL
Sbjct: 256 SIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEAWM 315
Query: 292 XXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQ--VMRSPIIMKRL 348
M P+ M+E EIQ+ G W Q ++R I K++
Sbjct: 316 ILKQVHDTNMRAKGTPEKVFTVSNIKTPKQMDEFIEIQSSTGTWYQRWLVRFKTIFKQV 374
Score = 41.1 bits (92), Expect = 0.010
Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
I+AL++DRIGR + ++ G M+ CC F N + + L +I A+N + +
Sbjct: 555 ISALLMDRIGRLK-MIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIA-AWNALDV 612
Query: 453 YTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+PT R + + + + G+I+ + + + + +L +LV G
Sbjct: 613 ITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLVGG 667
>BC030011-1|AAH30011.1| 683|Homo sapiens SV2B protein protein.
Length = 683
Score = 66.5 bits (155), Expect = 2e-10
Identities = 58/239 (24%), Positives = 97/239 (40%), Gaps = 20/239 (8%)
Query: 130 AEFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
AE ++ K+ ++G I +GM+ ILG ++D+ GRK L +S + +L +F
Sbjct: 136 AEKDMCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFV 195
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK 249
Y ++ + I P + E L ++KR ++LGI GG+ + MA
Sbjct: 196 QGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAW 255
Query: 250 T----------------FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXX-- 291
+ F WR F++V P + + + F+PES R+LL
Sbjct: 256 SIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEAWM 315
Query: 292 XXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQ--VMRSPIIMKRL 348
M P+ M+E EIQ+ G W Q ++R I K++
Sbjct: 316 ILKQVHDTNMRAKGTPEKVFTVSNIKTPKQMDEFIEIQSSTGTWYQRWLVRFKTIFKQV 374
Score = 41.1 bits (92), Expect = 0.010
Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
I+AL++DRIGR + ++ G M+ CC F N + + L +I A+N + +
Sbjct: 555 ISALLMDRIGRLK-MIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIA-AWNALDV 612
Query: 453 YTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+PT R + + + + G+I+ + + + + +L +LV G
Sbjct: 613 ITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLVGG 667
>AB018278-1|BAA34455.2| 707|Homo sapiens KIAA0735 protein protein.
Length = 707
Score = 66.5 bits (155), Expect = 2e-10
Identities = 58/239 (24%), Positives = 97/239 (40%), Gaps = 20/239 (8%)
Query: 130 AEFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
AE ++ K+ ++G I +GM+ ILG ++D+ GRK L +S + +L +F
Sbjct: 160 AEKDMCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFV 219
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK 249
Y ++ + I P + E L ++KR ++LGI GG+ + MA
Sbjct: 220 QGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAW 279
Query: 250 T----------------FQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXX-- 291
+ F WR F++V P + + + F+PES R+LL
Sbjct: 280 SIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEAWM 339
Query: 292 XXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQ--VMRSPIIMKRL 348
M P+ M+E EIQ+ G W Q ++R I K++
Sbjct: 340 ILKQVHDTNMRAKGTPEKVFTVSNIKTPKQMDEFIEIQSSTGTWYQRWLVRFKTIFKQV 398
Score = 41.1 bits (92), Expect = 0.010
Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
I+AL++DRIGR + ++ G M+ CC F N + + L +I A+N + +
Sbjct: 579 ISALLMDRIGRLK-MIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIA-AWNALDV 636
Query: 453 YTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+PT R + + + + G+I+ + + + + +L +LV G
Sbjct: 637 ITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLVGG 691
>BC090870-1|AAH90870.1| 449|Homo sapiens SLC22A17 protein protein.
Length = 449
Score = 64.9 bits (151), Expect = 7e-10
Identities = 81/384 (21%), Positives = 147/384 (38%), Gaps = 10/384 (2%)
Query: 129 VAEFNLACQ-EWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKA 187
+ +++L C W+ L + +G LGY +DRFGR+ ++L+ LVG G A
Sbjct: 16 IGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGA 75
Query: 188 FSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGG-VCFAL 246
+ S + + FL A Y++ +EL +R L A G ++ +GG F
Sbjct: 76 AAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQR-LRVALAGELVGVGGHFLFLG 134
Query: 247 MAKTFQYWRTFILVVYPPALLFLSYIY--FLPESIRWLLSXXXXXXXXXXXXXXXXMNNV 304
+A + WR ++ P +LFL Y + ES RWL+ N
Sbjct: 135 LALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNR- 193
Query: 305 XXXXXXXXXXXXDKPQTMEEKKEIQNEPGI-WSQVMRSPIIMKRLAICSWW-WITCTFVF 362
+ Q +E + ++ ++ I K L I + +I
Sbjct: 194 -PHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRH 252
Query: 363 YGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIP 422
+ D Y +L + +DR GR+ LL+ + G++ +
Sbjct: 253 CYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLL 312
Query: 423 FVRNHIVWLSIFLY-LLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVA 481
+ +++ +I + +LG + A + +E+ PT R L +G +G +
Sbjct: 313 GLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSG 372
Query: 482 PQMPLLEIYVKWLPSVLFGCTALV 505
P L + +L V+ AL+
Sbjct: 373 PAQRLHMGHGAFLQHVVLAACALL 396
Score = 31.5 bits (68), Expect = 7.9
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 159 LGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTI 218
LG DRFGR+ L+LS TL G+ + Y + + S+ A+ + T+
Sbjct: 284 LGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTL 343
Query: 219 ELLGQDKRVLTTAFLGIVISMG--GVCFALMAKTFQYWRTFI--LVVYPPALLFLSYIYF 274
+ LG+++++G G + F+ +V+ ALL + I
Sbjct: 344 LAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIML 403
Query: 275 LPESIRWLL 283
LPE+ R LL
Sbjct: 404 LPETKRKLL 412
>AK127610-1|BAC87056.1| 248|Homo sapiens protein ( Homo sapiens
cDNA FLJ45708 fis, clone FEHRT2002708, weakly similar
to Mus musculus solute carrier family 22 (organic cation
transporter). ).
Length = 248
Score = 62.1 bits (144), Expect = 5e-09
Identities = 47/203 (23%), Positives = 82/203 (40%), Gaps = 2/203 (0%)
Query: 151 GMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTF 210
GM+V + G++SDRFGRK L S + ++GT AF+ + +Y + FL A S
Sbjct: 3 GMMVGGNLYGHLSDRFGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSII 62
Query: 211 PASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLS 270
+ +L +E + + S+G + +A + LV+ P +F
Sbjct: 63 VNTVLLIVEWITHQFCAMALTLTLCAASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFL 122
Query: 271 YIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQN 330
+ +L ES RWL+ N + TM+++ E
Sbjct: 123 FSRWLAESARWLIINNKPEEGLKELRKAAHRNGMKNAEDILTMEVL--KSTMKQELEAAQ 180
Query: 331 EPGIWSQVMRSPIIMKRLAICSW 353
+ +++R P I KR+ S+
Sbjct: 181 KKHSLCELLRIPNICKRICFLSF 203
>BC040876-1|AAH40876.1| 341|Homo sapiens C6orf85 protein protein.
Length = 341
Score = 61.7 bits (143), Expect = 6e-09
Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 2/171 (1%)
Query: 103 PCSADTSFSQEALACDHWIYANN-NTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILG 160
P D + + + A D+ I A +V++++L C WK + +G++ I G
Sbjct: 169 PDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITG 228
Query: 161 YISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIEL 220
I+D GR+ L+ S + + G A SV+ M+ + F E A Y L IEL
Sbjct: 229 CIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIEL 288
Query: 221 LGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSY 271
KR + T V G +A + W+ ++ P LL L Y
Sbjct: 289 CPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLY 339
>AL583834-7|CAI14466.1| 211|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 211
Score = 61.7 bits (143), Expect = 6e-09
Identities = 43/169 (25%), Positives = 76/169 (44%)
Query: 338 VMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALV 397
+ R+P + C W F +YGL+++ L + Y +L + L
Sbjct: 30 LFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLS 89
Query: 398 LDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSEL 457
+ GR+ + + ++ V + + S L ++GK AF Y++TSEL
Sbjct: 90 VRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSEL 149
Query: 458 FPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVA 506
+PT R + + ++VGR+G +AP LL+ LP + +G AL+A
Sbjct: 150 YPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLA 198
>AL445309-6|CAI40959.1| 213|Homo sapiens chromosome 6 open reading
frame 85 protein.
Length = 213
Score = 61.7 bits (143), Expect = 6e-09
Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 2/171 (1%)
Query: 103 PCSADTSFSQEALACDHWIYANN-NTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILG 160
P D + + + A D+ I A +V++++L C WK + +G++ I G
Sbjct: 41 PDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITG 100
Query: 161 YISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIEL 220
I+D GR+ L+ S + + G A SV+ M+ + F E A Y L IEL
Sbjct: 101 CIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIEL 160
Query: 221 LGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSY 271
KR + T V G +A + W+ ++ P LL L Y
Sbjct: 161 CPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLY 211
>AL160398-1|CAI12303.1| 213|Homo sapiens chromosome 6 open reading
frame 85 protein.
Length = 213
Score = 61.7 bits (143), Expect = 6e-09
Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 2/171 (1%)
Query: 103 PCSADTSFSQEALACDHWIYANN-NTIVAEFNLACQE-WKRTLVGTIHNIGMLVSLPILG 160
P D + + + A D+ I A +V++++L C WK + +G++ I G
Sbjct: 41 PDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITG 100
Query: 161 YISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIEL 220
I+D GR+ L+ S + + G A SV+ M+ + F E A Y L IEL
Sbjct: 101 CIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIEL 160
Query: 221 LGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSY 271
KR + T V G +A + W+ ++ P LL L Y
Sbjct: 161 CPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLY 211
>BC020565-1|AAH20565.1| 538|Homo sapiens solute carrier family 22
(organic cation transporter), member 17 protein.
Length = 538
Score = 60.5 bits (140), Expect = 1e-08
Identities = 46/159 (28%), Positives = 75/159 (47%), Gaps = 5/159 (3%)
Query: 129 VAEFNLACQ-EWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKA 187
+ +++L C W+ L + +G LGY +DRFGR+ ++L+ LVG G A
Sbjct: 87 IGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGA 146
Query: 188 FSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGG-VCFAL 246
+ S + + FL A Y++ +EL +R L A G ++ +GG F
Sbjct: 147 AAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQR-LRVALAGELVGVGGHFLFLG 205
Query: 247 MAKTFQYWRTFILVVYPPALLFLSYIY--FLPESIRWLL 283
+A + WR ++ P +LFL Y + ES RWL+
Sbjct: 206 LALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLI 244
>BC111015-1|AAI11016.1| 403|Homo sapiens SLC22A17 protein protein.
Length = 403
Score = 59.7 bits (138), Expect = 3e-08
Identities = 76/353 (21%), Positives = 135/353 (38%), Gaps = 9/353 (2%)
Query: 159 LGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTI 218
LGY +DRFGR+ ++L+ LVG G A + S + + FL A Y++ +
Sbjct: 1 LGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRL 60
Query: 219 ELLGQDKRVLTTAFLGIVISMGG-VCFALMAKTFQYWRTFILVVYPPALLFLSYIY--FL 275
EL +R L A G ++ +GG F +A + WR ++ P +LFL Y +
Sbjct: 61 ELCDPTQR-LRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLF 119
Query: 276 PESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGI- 334
ES RWL+ N + Q +E +
Sbjct: 120 LESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLGEEAQEALQDLENTCPLPATSSFS 177
Query: 335 WSQVMRSPIIMKRLAICSWW-WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXXXXXXI 393
++ ++ I K L I + +I + D Y +L
Sbjct: 178 FASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVF 237
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLY-LLGKVAITQAFNGIYM 452
+ +DR GR+ LL+ + G++ + + +++ +I + +LG + A +
Sbjct: 238 LGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTL 297
Query: 453 YTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALV 505
+E+ PT R L +G +G + P L + +L V+ AL+
Sbjct: 298 LAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALL 350
Score = 31.5 bits (68), Expect = 7.9
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 159 LGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTI 218
LG DRFGR+ L+LS TL G+ + Y + + S+ A+ + T+
Sbjct: 238 LGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTL 297
Query: 219 ELLGQDKRVLTTAFLGIVISMG--GVCFALMAKTFQYWRTFI--LVVYPPALLFLSYIYF 274
+ LG+++++G G + F+ +V+ ALL + I
Sbjct: 298 LAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIML 357
Query: 275 LPESIRWLL 283
LPE+ R LL
Sbjct: 358 LPETKRKLL 366
>BC094722-1|AAH94722.1| 548|Homo sapiens SV2 related protein
homolog (rat) protein.
Length = 548
Score = 58.4 bits (135), Expect = 6e-08
Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 4/146 (2%)
Query: 139 WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIV 198
W+ L+ ++ +GM+ S + G ISD++GRK L +S G L AF+ Y +++
Sbjct: 120 WQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVL 179
Query: 199 EFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMG---GVCFALMAKTFQYWR 255
L G P S L E L R + + ++G V A+ WR
Sbjct: 180 RGLVGF-GIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWR 238
Query: 256 TFILVVYPPALLFLSYIYFLPESIRW 281
+++ P LLF ++LPES R+
Sbjct: 239 WLLILSAVPLLLFAVLCFWLPESARY 264
Score = 57.2 bits (132), Expect = 1e-07
Identities = 35/137 (25%), Positives = 67/137 (48%), Gaps = 4/137 (2%)
Query: 372 LAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWL 431
L+ + Y + + + ++DR+GRK+++ + F++ C + F+ L
Sbjct: 368 LSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSF-CSLLLFICVGRNVL 426
Query: 432 SIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAP--QMPLLEI 489
++ L++ + I+ F Y+YT E++PT R L CS + R+G+++ P +LE
Sbjct: 427 TLLLFI-ARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLES 485
Query: 490 YVKWLPSVLFGCTALVA 506
V +V GC L A
Sbjct: 486 SVYLTLAVYSGCCLLAA 502
>BC033587-1|AAH33587.1| 548|Homo sapiens SV2 related protein
homolog (rat) protein.
Length = 548
Score = 58.4 bits (135), Expect = 6e-08
Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 4/146 (2%)
Query: 139 WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIV 198
W+ L+ ++ +GM+ S + G ISD++GRK L +S G L AF+ Y +++
Sbjct: 120 WQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVL 179
Query: 199 EFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMG---GVCFALMAKTFQYWR 255
L G P S L E L R + + ++G V A+ WR
Sbjct: 180 RGLVGF-GIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWR 238
Query: 256 TFILVVYPPALLFLSYIYFLPESIRW 281
+++ P LLF ++LPES R+
Sbjct: 239 WLLILSAVPLLLFAVLCFWLPESARY 264
Score = 57.2 bits (132), Expect = 1e-07
Identities = 35/137 (25%), Positives = 67/137 (48%), Gaps = 4/137 (2%)
Query: 372 LAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWL 431
L+ + Y + + + ++DR+GRK+++ + F++ C + F+ L
Sbjct: 368 LSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSF-CSLLLFICVGRNVL 426
Query: 432 SIFLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAP--QMPLLEI 489
++ L++ + I+ F Y+YT E++PT R L CS + R+G+++ P +LE
Sbjct: 427 TLLLFI-ARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLES 485
Query: 490 YVKWLPSVLFGCTALVA 506
V +V GC L A
Sbjct: 486 SVYLTLAVYSGCCLLAA 502
>BX537754-1|CAD97824.1| 742|Homo sapiens hypothetical protein
protein.
Length = 742
Score = 58.0 bits (134), Expect = 8e-08
Identities = 43/170 (25%), Positives = 78/170 (45%), Gaps = 16/170 (9%)
Query: 130 AEFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
AE ++ + + ++G I +GM+V + G ++DR GR+ L++S ++ V +F
Sbjct: 193 AEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFV 252
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA- 248
Y ++ L + + P + E L Q+KR ++L + +GGV A MA
Sbjct: 253 QGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAW 312
Query: 249 -------------KTFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F+LV P++ + + PES R+ L
Sbjct: 313 AIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFL 362
Score = 45.6 bits (103), Expect = 5e-04
Identities = 29/115 (25%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++D+IGR R L ++ VSC + F + +++ L L G V+I ++N + +
Sbjct: 614 VSALLMDKIGRLRMLAGSSVMSCVSCFFLSFGNSESAMIAL-LCLFGGVSIA-SWNALDV 671
Query: 453 YTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+P+ R + F + + ++ +++ + + + +LF AL G
Sbjct: 672 LTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALG 726
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
DR+GR++ LLI V V FV+ + +L F LL V I + ++ Y SE
Sbjct: 227 DRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFL--FCRLLSGVGIGGSIPIVFSYFSEFL 284
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG + A M
Sbjct: 285 AQEKRGEHLSWLCMFWMIGGVYAAAM 310
>BC045111-1|AAH45111.1| 742|Homo sapiens synaptic vesicle
glycoprotein 2A protein.
Length = 742
Score = 58.0 bits (134), Expect = 8e-08
Identities = 43/170 (25%), Positives = 78/170 (45%), Gaps = 16/170 (9%)
Query: 130 AEFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
AE ++ + + ++G I +GM+V + G ++DR GR+ L++S ++ V +F
Sbjct: 193 AEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFV 252
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA- 248
Y ++ L + + P + E L Q+KR ++L + +GGV A MA
Sbjct: 253 QGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAW 312
Query: 249 -------------KTFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F+LV P++ + + PES R+ L
Sbjct: 313 AIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFL 362
Score = 45.6 bits (103), Expect = 5e-04
Identities = 29/115 (25%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++D+IGR R L ++ VSC + F + +++ L L G V+I ++N + +
Sbjct: 614 VSALLMDKIGRLRMLAGSSVMSCVSCFFLSFGNSESAMIAL-LCLFGGVSIA-SWNALDV 671
Query: 453 YTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+P+ R + F + + ++ +++ + + + +LF AL G
Sbjct: 672 LTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALG 726
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
DR+GR++ LLI V V FV+ + +L F LL V I + ++ Y SE
Sbjct: 227 DRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFL--FCRLLSGVGIGGSIPIVFSYFSEFL 284
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG + A M
Sbjct: 285 AQEKRGEHLSWLCMFWMIGGVYAAAM 310
>BC000776-1|AAH00776.2| 604|Homo sapiens SV2A protein protein.
Length = 604
Score = 58.0 bits (134), Expect = 8e-08
Identities = 43/170 (25%), Positives = 78/170 (45%), Gaps = 16/170 (9%)
Query: 130 AEFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
AE ++ + + ++G I +GM+V + G ++DR GR+ L++S ++ V +F
Sbjct: 55 AEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFV 114
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA- 248
Y ++ L + + P + E L Q+KR ++L + +GGV A MA
Sbjct: 115 QGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAW 174
Query: 249 -------------KTFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F+LV P++ + + PES R+ L
Sbjct: 175 AIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFL 224
Score = 45.6 bits (103), Expect = 5e-04
Identities = 29/115 (25%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++D+IGR R L ++ VSC + F + +++ L L G V+I ++N + +
Sbjct: 476 VSALLMDKIGRLRMLAGSSVMSCVSCFFLSFGNSESAMIAL-LCLFGGVSIA-SWNALDV 533
Query: 453 YTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+P+ R + F + + ++ +++ + + + +LF AL G
Sbjct: 534 LTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALG 588
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
DR+GR++ LLI V V FV+ + +L F LL V I + ++ Y SE
Sbjct: 89 DRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFL--FCRLLSGVGIGGSIPIVFSYFSEFL 146
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG + A M
Sbjct: 147 AQEKRGEHLSWLCMFWMIGGVYAAAM 172
>AL591493-21|CAI12573.1| 682|Homo sapiens synaptic vesicle
glycoprotein 2A protein.
Length = 682
Score = 58.0 bits (134), Expect = 8e-08
Identities = 43/170 (25%), Positives = 78/170 (45%), Gaps = 16/170 (9%)
Query: 130 AEFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
AE ++ + + ++G I +GM+V + G ++DR GR+ L++S ++ V +F
Sbjct: 193 AEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFV 252
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA- 248
Y ++ L + + P + E L Q+KR ++L + +GGV A MA
Sbjct: 253 QGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAW 312
Query: 249 -------------KTFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F+LV P++ + + PES R+ L
Sbjct: 313 AIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFL 362
Score = 37.9 bits (84), Expect = 0.091
Identities = 23/71 (32%), Positives = 42/71 (59%), Gaps = 2/71 (2%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++D+IGR R L ++ VSC + F + +++ L L G V+I ++N + +
Sbjct: 614 VSALLMDKIGRLRMLAGSSVMSCVSCFFLSFGNSESAMIAL-LCLFGGVSIA-SWNALDV 671
Query: 453 YTSELFPTRAR 463
T EL+P+ R
Sbjct: 672 LTVELYPSDKR 682
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
DR+GR++ LLI V V FV+ + +L F LL V I + ++ Y SE
Sbjct: 227 DRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFL--FCRLLSGVGIGGSIPIVFSYFSEFL 284
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG + A M
Sbjct: 285 AQEKRGEHLSWLCMFWMIGGVYAAAM 310
>AL591493-20|CAI12572.1| 742|Homo sapiens synaptic vesicle
glycoprotein 2A protein.
Length = 742
Score = 58.0 bits (134), Expect = 8e-08
Identities = 43/170 (25%), Positives = 78/170 (45%), Gaps = 16/170 (9%)
Query: 130 AEFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
AE ++ + + ++G I +GM+V + G ++DR GR+ L++S ++ V +F
Sbjct: 193 AEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFV 252
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA- 248
Y ++ L + + P + E L Q+KR ++L + +GGV A MA
Sbjct: 253 QGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAW 312
Query: 249 -------------KTFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F+LV P++ + + PES R+ L
Sbjct: 313 AIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFL 362
Score = 45.6 bits (103), Expect = 5e-04
Identities = 29/115 (25%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++D+IGR R L ++ VSC + F + +++ L L G V+I ++N + +
Sbjct: 614 VSALLMDKIGRLRMLAGSSVMSCVSCFFLSFGNSESAMIAL-LCLFGGVSIA-SWNALDV 671
Query: 453 YTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+P+ R + F + + ++ +++ + + + +LF AL G
Sbjct: 672 LTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALG 726
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
DR+GR++ LLI V V FV+ + +L F LL V I + ++ Y SE
Sbjct: 227 DRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFL--FCRLLSGVGIGGSIPIVFSYFSEFL 284
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG + A M
Sbjct: 285 AQEKRGEHLSWLCMFWMIGGVYAAAM 310
>AK075480-1|BAC11645.1| 682|Homo sapiens protein ( Homo sapiens
cDNA PSEC0174 fis, clone NT2RP2002760, highly similar to
SYNAPTIC VESICLE PROTEIN 2. ).
Length = 682
Score = 58.0 bits (134), Expect = 8e-08
Identities = 43/170 (25%), Positives = 78/170 (45%), Gaps = 16/170 (9%)
Query: 130 AEFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
AE ++ + + ++G I +GM+V + G ++DR GR+ L++S ++ V +F
Sbjct: 193 AEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFV 252
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA- 248
Y ++ L + + P + E L Q+KR ++L + +GGV A MA
Sbjct: 253 QGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAW 312
Query: 249 -------------KTFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F+LV P++ + + PES R+ L
Sbjct: 313 AIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFL 362
Score = 37.9 bits (84), Expect = 0.091
Identities = 23/71 (32%), Positives = 42/71 (59%), Gaps = 2/71 (2%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++D+IGR R L ++ VSC + F + +++ L L G V+I ++N + +
Sbjct: 614 VSALLMDKIGRLRMLAGSSVMSCVSCFFLSFGNSESAMIAL-LCLFGGVSIA-SWNALDV 671
Query: 453 YTSELFPTRAR 463
T EL+P+ R
Sbjct: 672 LTVELYPSDKR 682
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
DR+GR++ LLI V V FV+ + +L F LL V I + ++ Y SE
Sbjct: 227 DRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFL--FCRLLSGVGIGGSIPIVFSYFSEFL 284
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG + A M
Sbjct: 285 AQEKRGEHLSWLCMFWMIGGVYAAAM 310
>AB018279-1|BAA34456.2| 748|Homo sapiens KIAA0736 protein protein.
Length = 748
Score = 58.0 bits (134), Expect = 8e-08
Identities = 43/170 (25%), Positives = 78/170 (45%), Gaps = 16/170 (9%)
Query: 130 AEFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
AE ++ + + ++G I +GM+V + G ++DR GR+ L++S ++ V +F
Sbjct: 199 AEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFV 258
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA- 248
Y ++ L + + P + E L Q+KR ++L + +GGV A MA
Sbjct: 259 QGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAW 318
Query: 249 -------------KTFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F+LV P++ + + PES R+ L
Sbjct: 319 AIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFL 368
Score = 45.6 bits (103), Expect = 5e-04
Identities = 29/115 (25%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++D+IGR R L ++ VSC + F + +++ L L G V+I ++N + +
Sbjct: 620 VSALLMDKIGRLRMLAGSSVMSCVSCFFLSFGNSESAMIAL-LCLFGGVSIA-SWNALDV 677
Query: 453 YTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+P+ R + F + + ++ +++ + + + +LF AL G
Sbjct: 678 LTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALG 732
Score = 37.1 bits (82), Expect = 0.16
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
DR+GR++ LLI V V FV+ + +L F LL V I + ++ Y SE
Sbjct: 233 DRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFL--FCRLLSGVGIGGSIPIVFSYFSEFL 290
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG + A M
Sbjct: 291 AQEKRGEHLSWLCMFWMIGGVYAAAM 316
>AY358258-1|AAQ88625.1| 245|Homo sapiens trans-like protein
protein.
Length = 245
Score = 57.6 bits (133), Expect = 1e-07
Identities = 36/145 (24%), Positives = 67/145 (46%), Gaps = 2/145 (1%)
Query: 119 HWIYANNNTIVAE--FNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSC 176
H ++++ T +A F +A + +K + + G+ V + G +SDRFGRK +
Sbjct: 87 HVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGF 146
Query: 177 TLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIV 236
L + FS SYE + + FL + +++L E +G L + G+
Sbjct: 147 ALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLF 206
Query: 237 ISMGGVCFALMAKTFQYWRTFILVV 261
++G +AL+ + WRT ++V
Sbjct: 207 FAVGIAQYALLGYFIRSWRTLAILV 231
>AL365318-1|CAH70685.1| 245|Homo sapiens solute carrier family 22
(organic cation transporter), member 15 protein.
Length = 245
Score = 57.6 bits (133), Expect = 1e-07
Identities = 36/145 (24%), Positives = 67/145 (46%), Gaps = 2/145 (1%)
Query: 119 HWIYANNNTIVAE--FNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSC 176
H ++++ T +A F +A + +K + + G+ V + G +SDRFGRK +
Sbjct: 87 HVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGF 146
Query: 177 TLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIV 236
L + FS SYE + + FL + +++L E +G L + G+
Sbjct: 147 ALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLF 206
Query: 237 ISMGGVCFALMAKTFQYWRTFILVV 261
++G +AL+ + WRT ++V
Sbjct: 207 FAVGIAQYALLGYFIRSWRTLAILV 231
>AL357137-1|CAH70379.1| 245|Homo sapiens solute carrier family 22
(organic cation transporter), member 15 protein.
Length = 245
Score = 57.6 bits (133), Expect = 1e-07
Identities = 36/145 (24%), Positives = 67/145 (46%), Gaps = 2/145 (1%)
Query: 119 HWIYANNNTIVAE--FNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSC 176
H ++++ T +A F +A + +K + + G+ V + G +SDRFGRK +
Sbjct: 87 HVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGF 146
Query: 177 TLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIV 236
L + FS SYE + + FL + +++L E +G L + G+
Sbjct: 147 ALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLF 206
Query: 237 ISMGGVCFALMAKTFQYWRTFILVV 261
++G +AL+ + WRT ++V
Sbjct: 207 FAVGIAQYALLGYFIRSWRTLAILV 231
>AK131327-1|BAD18487.1| 349|Homo sapiens protein ( Homo sapiens
cDNA FLJ16331 fis, clone SYNOV2013637, moderately
similar to Homo sapiens putative renal organic anion
transporter 1 ).
Length = 349
Score = 56.0 bits (129), Expect = 3e-07
Identities = 51/192 (26%), Positives = 80/192 (41%), Gaps = 12/192 (6%)
Query: 21 VLGQLGQAGQFHLRXXXXXXXXXXXXGMLHTTYIFLAGSVPYRCTVPECESLNTTDFNPV 80
+L LG G+F L + F A P+ C P + +T+ +
Sbjct: 8 LLDALGSMGRFQLNHTALLLLPCGLLACHNFLQNFTAAVPPHHCRGPANHTEASTNDSGA 67
Query: 81 WLPNAAVE----GQGERCSRRV-PLTQPCSADTSFSQEAL-AC-DHWIYANN---NTIVA 130
WL A + G E C R P S ++S A C D W+Y + +TIV
Sbjct: 68 WL-RATIPLDQLGAPEPCRRFTKPQWALLSPNSSIPGAATEGCKDGWVYNRSVFPSTIVM 126
Query: 131 EFNLACQ-EWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
E++L C+ R L +++ G+LV + G ++DR G K L+ S + G A+
Sbjct: 127 EWDLVCEARTLRDLAQSVYMAGVLVGAAVFGSLADRLGCKGPLVWSYLQLAASGAATAYF 186
Query: 190 VSYEMYVIVEFL 201
S+ Y + FL
Sbjct: 187 SSFSAYCVFRFL 198
>BC070149-1|AAH70149.1| 617|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 12 protein.
Length = 617
Score = 55.6 bits (128), Expect = 4e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 6/154 (3%)
Query: 134 LACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYE 193
L+C E + + + IG L++ G + DR+GR+ A+ILS L+G+ + S+SY
Sbjct: 74 LSCHEQEMVVSSLV--IGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYT 131
Query: 194 MYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFAL----MAK 249
+ ++ ++ + + A+ + E+ Q +R L + ++I +G + + A
Sbjct: 132 VLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFAN 191
Query: 250 TFQYWRTFILVVYPPALLFLSYIYFLPESIRWLL 283
F W+ +V P +L +YFLP S R+L+
Sbjct: 192 VFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLV 225
>AY046419-1|AAL02327.1| 617|Homo sapiens glucose transporter
protein 12 protein.
Length = 617
Score = 55.6 bits (128), Expect = 4e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 6/154 (3%)
Query: 134 LACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYE 193
L+C E + + + IG L++ G + DR+GR+ A+ILS L+G+ + S+SY
Sbjct: 74 LSCHEQEMVVSSLV--IGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYT 131
Query: 194 MYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFAL----MAK 249
+ ++ ++ + + A+ + E+ Q +R L + ++I +G + + A
Sbjct: 132 VLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFAN 191
Query: 250 TFQYWRTFILVVYPPALLFLSYIYFLPESIRWLL 283
F W+ +V P +L +YFLP S R+L+
Sbjct: 192 VFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLV 225
>AL449363-1|CAI17977.1| 617|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 12 protein.
Length = 617
Score = 55.6 bits (128), Expect = 4e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 6/154 (3%)
Query: 134 LACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYE 193
L+C E + + + IG L++ G + DR+GR+ A+ILS L+G+ + S+SY
Sbjct: 74 LSCHEQEMVVSSLV--IGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYT 131
Query: 194 MYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFAL----MAK 249
+ ++ ++ + + A+ + E+ Q +R L + ++I +G + + A
Sbjct: 132 VLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFAN 191
Query: 250 TFQYWRTFILVVYPPALLFLSYIYFLPESIRWLL 283
F W+ +V P +L +YFLP S R+L+
Sbjct: 192 VFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLV 225
>AL035699-6|CAD92514.2| 617|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 12 protein.
Length = 617
Score = 55.6 bits (128), Expect = 4e-07
Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 6/154 (3%)
Query: 134 LACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYE 193
L+C E + + + IG L++ G + DR+GR+ A+ILS L+G+ + S+SY
Sbjct: 74 LSCHEQEMVVSSLV--IGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYT 131
Query: 194 MYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFAL----MAK 249
+ ++ ++ + + A+ + E+ Q +R L + ++I +G + + A
Sbjct: 132 VLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFAN 191
Query: 250 TFQYWRTFILVVYPPALLFLSYIYFLPESIRWLL 283
F W+ +V P +L +YFLP S R+L+
Sbjct: 192 VFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLV 225
>BC100827-1|AAI00828.1| 727|Homo sapiens synaptic vesicle
glycoprotein 2C protein.
Length = 727
Score = 54.8 bits (126), Expect = 7e-07
Identities = 39/156 (25%), Positives = 73/156 (46%), Gaps = 16/156 (10%)
Query: 144 VGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLET 203
+G+I +GM+V G ++D+ GRK +L++ ++ G L +F Y ++ L
Sbjct: 193 LGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSG 252
Query: 204 IAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA--------------K 249
P + E+L ++KR ++L + +GG+ + MA
Sbjct: 253 FGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGS 312
Query: 250 TFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F++V P + + + F+PES R+LL
Sbjct: 313 AYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLL 348
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++DRIGR L ++ G+SC + F + + + + L L + I+ A+N + +
Sbjct: 599 VSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGM-LCLYNGLTIS-AWNSLDV 656
Query: 453 YTSELFPTRARHS----LLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+PT R + L A C +G+++ + + K +P +L T LV G
Sbjct: 657 VTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSI---TKSIP-ILLASTVLVCG 711
Score = 38.3 bits (85), Expect = 0.069
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
D++GRK+SLLI V G FV+ + +L F LL I A ++ Y +E+
Sbjct: 213 DKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFL--FCRLLSGFGIGGAIPTVFSYFAEVL 270
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG I A M
Sbjct: 271 AREKRGEHLSWLCMFWMIGGIYASAM 296
>BC100826-1|AAI00827.1| 727|Homo sapiens synaptic vesicle
glycoprotein 2C protein.
Length = 727
Score = 54.8 bits (126), Expect = 7e-07
Identities = 39/156 (25%), Positives = 73/156 (46%), Gaps = 16/156 (10%)
Query: 144 VGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLET 203
+G+I +GM+V G ++D+ GRK +L++ ++ G L +F Y ++ L
Sbjct: 193 LGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSG 252
Query: 204 IAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA--------------K 249
P + E+L ++KR ++L + +GG+ + MA
Sbjct: 253 FGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGS 312
Query: 250 TFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F++V P + + + F+PES R+LL
Sbjct: 313 AYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLL 348
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++DRIGR L ++ G+SC + F + + + + L L + I+ A+N + +
Sbjct: 599 VSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGM-LCLYNGLTIS-AWNSLDV 656
Query: 453 YTSELFPTRARHS----LLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+PT R + L A C +G+++ + + K +P +L T LV G
Sbjct: 657 VTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSI---TKSIP-ILLASTVLVCG 711
Score = 38.3 bits (85), Expect = 0.069
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
D++GRK+SLLI V G FV+ + +L F LL I A ++ Y +E+
Sbjct: 213 DKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFL--FCRLLSGFGIGGAIPTVFSYFAEVL 270
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG I A M
Sbjct: 271 AREKRGEHLSWLCMFWMIGGIYASAM 296
>BC100825-1|AAI00826.1| 727|Homo sapiens synaptic vesicle
glycoprotein 2C protein.
Length = 727
Score = 54.8 bits (126), Expect = 7e-07
Identities = 39/156 (25%), Positives = 73/156 (46%), Gaps = 16/156 (10%)
Query: 144 VGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLET 203
+G+I +GM+V G ++D+ GRK +L++ ++ G L +F Y ++ L
Sbjct: 193 LGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSG 252
Query: 204 IAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA--------------K 249
P + E+L ++KR ++L + +GG+ + MA
Sbjct: 253 FGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGS 312
Query: 250 TFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F++V P + + + F+PES R+LL
Sbjct: 313 AYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLL 348
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++DRIGR L ++ G+SC + F + + + + L L + I+ A+N + +
Sbjct: 599 VSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGM-LCLYNGLTIS-AWNSLDV 656
Query: 453 YTSELFPTRARHS----LLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+PT R + L A C +G+++ + + K +P +L T LV G
Sbjct: 657 VTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSI---TKSIP-ILLASTVLVCG 711
Score = 38.3 bits (85), Expect = 0.069
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
D++GRK+SLLI V G FV+ + +L F LL I A ++ Y +E+
Sbjct: 213 DKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFL--FCRLLSGFGIGGAIPTVFSYFAEVL 270
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG I A M
Sbjct: 271 AREKRGEHLSWLCMFWMIGGIYASAM 296
>BC100824-1|AAI00825.1| 727|Homo sapiens synaptic vesicle
glycoprotein 2C protein.
Length = 727
Score = 53.2 bits (122), Expect = 2e-06
Identities = 39/156 (25%), Positives = 72/156 (46%), Gaps = 16/156 (10%)
Query: 144 VGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLET 203
+G+I +GM+V G ++D+ GRK +L++ ++ G L +F Y ++ L
Sbjct: 193 LGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSG 252
Query: 204 IAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA--------------K 249
P + E+L ++KR ++L + +GG+ + MA
Sbjct: 253 FGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGS 312
Query: 250 TFQY--WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+Q+ WR F++V P + + + F+PES R LL
Sbjct: 313 AYQFHSWRVFVIVCALPCVSSVVALTFMPESPRSLL 348
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++DRIGR L ++ G+SC + F + + + + L L + I+ A+N + +
Sbjct: 599 VSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGM-LCLYNGLTIS-AWNSLDV 656
Query: 453 YTSELFPTRARHS----LLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+PT R + L A C +G+++ + + K +P +L T LV G
Sbjct: 657 VTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSI---TKSIP-ILLASTVLVCG 711
Score = 38.3 bits (85), Expect = 0.069
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Query: 399 DRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELF 458
D++GRK+SLLI V G FV+ + +L F LL I A ++ Y +E+
Sbjct: 213 DKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFL--FCRLLSGFGIGGAIPTVFSYFAEVL 270
Query: 459 PTRARHSLLAFCSMVGRIGSIVAPQM 484
R L++ M IG I A M
Sbjct: 271 AREKRGEHLSWLCMFWMIGGIYASAM 296
>AL583834-6|CAI14465.1| 147|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 147
Score = 52.4 bits (120), Expect = 4e-06
Identities = 46/138 (33%), Positives = 61/138 (44%), Gaps = 4/138 (2%)
Query: 131 EFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
E++L C Q+ T G+LV GY+SDRFGR+ L+++ V+G A S
Sbjct: 2 EWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAAS 61
Query: 190 VSYEMYVIVEFLETIAGAS-TFPASYILTIELLGQDKRVLTTA-FLGIVISMGGV-CFAL 246
VSY M+ I L A A T + EL D T A L GGV AL
Sbjct: 62 VSYVMFAITRTLTGSALAGFTIIVMPLGEAELEWLDVEHRTVAGVLSSTFWTGGVMLLAL 121
Query: 247 MAKTFQYWRTFILVVYPP 264
+ + WR +L V P
Sbjct: 122 VGYLIRDWRWLLLAVTLP 139
>AL583834-2|CAI14461.1| 278|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 278
Score = 47.6 bits (108), Expect = 1e-04
Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Query: 131 EFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFS 189
E++L C Q+ T G+LV GY+SDRFGR+ L+++ V+G A S
Sbjct: 192 EWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAAS 251
Query: 190 VSYEMYVIVEFL 201
VSY M+ I L
Sbjct: 252 VSYVMFAITRTL 263
>AY517500-1|AAS76641.1| 234|Homo sapiens putative integral membrane
transport protein protein.
Length = 234
Score = 46.8 bits (106), Expect = 2e-04
Identities = 40/188 (21%), Positives = 71/188 (37%), Gaps = 2/188 (1%)
Query: 166 FGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDK 225
FGRK L S + ++GT AF+ + +Y + FL A S + +L +E +
Sbjct: 4 FGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQF 63
Query: 226 RVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSX 285
+ S+G + +A + LV+ P +F + +L ES RWL+
Sbjct: 64 CAMALTLTLCAASIGHITLGGLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIIN 123
Query: 286 XXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIM 345
N + TM+++ E + +++R P I
Sbjct: 124 NKPEEGLKELTKAAHRNGMKNAEDILTMEVL--KSTMKQELEAAQKKHSLCELLRIPNIC 181
Query: 346 KRLAICSW 353
KR+ S+
Sbjct: 182 KRICFLSF 189
>AK091990-1|BAC03786.1| 234|Homo sapiens protein ( Homo sapiens
cDNA FLJ34671 fis, clone LIVER2001099, moderately
similar to Rattus norvegicus mRNA for putative integral
membrane ).
Length = 234
Score = 46.8 bits (106), Expect = 2e-04
Identities = 40/188 (21%), Positives = 71/188 (37%), Gaps = 2/188 (1%)
Query: 166 FGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDK 225
FGRK L S + ++GT AF+ + +Y + FL A S + +L +E +
Sbjct: 4 FGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQF 63
Query: 226 RVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSX 285
+ S+G + +A + LV+ P +F + +L ES RWL+
Sbjct: 64 CAMALTLTLCAASIGHITLGGLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIIN 123
Query: 286 XXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQNEPGIWSQVMRSPIIM 345
N + TM+++ E + +++R P I
Sbjct: 124 NKPEEGLKELTKAAHRNGMKNAEDILTMEVL--KSTMKQELEAAQKKHSLCELLRIPNIC 181
Query: 346 KRLAICSW 353
KR+ S+
Sbjct: 182 KRICFLSF 189
>BC121804-1|AAI21805.1| 492|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 1 protein.
Length = 492
Score = 45.6 bits (103), Expect = 5e-04
Identities = 67/285 (23%), Positives = 112/285 (39%), Gaps = 16/285 (5%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV---SYEMYVIVEFLET 203
I ++G ++ +G +RFGR+ ++++ L V L FS S+EM ++ F+
Sbjct: 71 IFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIG 130
Query: 204 I-AGAST-FPASYILTIELLGQDKRVLTTAFLGIVIS-MGGVCFAL--MAKTFQYWRTFI 258
+ G +T F Y+ + + T LGIV+ + F L + W +
Sbjct: 131 VYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLL 190
Query: 259 LVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDK 318
+++ PALL + F PES R+LL + +
Sbjct: 191 SIIFIPALLQCIVLPFCPESPRFLL--INRNEENRAKSVLKKLRGTADVTHDLQEMKEES 248
Query: 319 PQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYT 378
Q M EKK E S R PI++ + S VFY + + AG +
Sbjct: 249 RQMMREKKVTILEL-FRSPAYRQPILIAVVLQLSQQLSGINAVFY-YSTSIFEKAGVQQP 306
Query: 379 NYML--XXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAI 421
Y ++ V++R GR+ LIG + G++ CAI
Sbjct: 307 VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIG--LAGMAGCAI 349
>BC118590-1|AAI18591.1| 492|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 1 protein.
Length = 492
Score = 45.6 bits (103), Expect = 5e-04
Identities = 67/285 (23%), Positives = 112/285 (39%), Gaps = 16/285 (5%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV---SYEMYVIVEFLET 203
I ++G ++ +G +RFGR+ ++++ L V L FS S+EM ++ F+
Sbjct: 71 IFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIG 130
Query: 204 I-AGAST-FPASYILTIELLGQDKRVLTTAFLGIVIS-MGGVCFAL--MAKTFQYWRTFI 258
+ G +T F Y+ + + T LGIV+ + F L + W +
Sbjct: 131 VYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLL 190
Query: 259 LVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDK 318
+++ PALL + F PES R+LL + +
Sbjct: 191 SIIFIPALLQCIVLPFCPESPRFLL--INRNEENRAKSVLKKLRGTADVTHDLQEMKEES 248
Query: 319 PQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYT 378
Q M EKK E S R PI++ + S VFY + + AG +
Sbjct: 249 RQMMREKKVTILEL-FRSPAYRQPILIAVVLQLSQQLSGINAVFY-YSTSIFEKAGVQQP 306
Query: 379 NYML--XXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAI 421
Y ++ V++R GR+ LIG + G++ CAI
Sbjct: 307 VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIG--LAGMAGCAI 349
>AB208987-1|BAD92224.1| 517|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 1 variant
protein.
Length = 517
Score = 45.6 bits (103), Expect = 5e-04
Identities = 67/285 (23%), Positives = 112/285 (39%), Gaps = 16/285 (5%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV---SYEMYVIVEFLET 203
I ++G ++ +G +RFGR+ ++++ L V L FS S+EM ++ F+
Sbjct: 96 IFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIG 155
Query: 204 I-AGAST-FPASYILTIELLGQDKRVLTTAFLGIVIS-MGGVCFAL--MAKTFQYWRTFI 258
+ G +T F Y+ + + T LGIV+ + F L + W +
Sbjct: 156 VYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLL 215
Query: 259 LVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDK 318
+++ PALL + F PES R+LL + +
Sbjct: 216 SIIFIPALLQCIVLPFCPESPRFLL--INRNEENRAKSVLKKLRGTADVTHDLQEMKEES 273
Query: 319 PQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYT 378
Q M EKK E S R PI++ + S VFY + + AG +
Sbjct: 274 RQMMREKKVTILEL-FRSPAYRQPILIAVVLQLSQQLSGINAVFY-YSTSIFEKAGVQQP 331
Query: 379 NYML--XXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAI 421
Y ++ V++R GR+ LIG + G++ CAI
Sbjct: 332 VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIG--LAGMAGCAI 374
>K03195-1|AAA52571.1| 492|Homo sapiens SGLT1 protein.
Length = 492
Score = 45.2 bits (102), Expect = 6e-04
Identities = 67/285 (23%), Positives = 112/285 (39%), Gaps = 16/285 (5%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV---SYEMYVIVEFLET 203
I ++G ++ +G +RFGR+ ++++ L V L FS S+EM ++ F+
Sbjct: 71 IFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIG 130
Query: 204 I-AGAST-FPASYILTIELLGQDKRVLTTAFLGIVIS-MGGVCFAL--MAKTFQYWRTFI 258
+ G +T F Y+ + + T LGIV+ + F L + W +
Sbjct: 131 VYCGLTTGFVPMYVGEVSPTAFRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLL 190
Query: 259 LVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDK 318
+++ PALL + F PES R+LL + +
Sbjct: 191 SIIFIPALLQCIVLPFCPESPRFLL--INRNEENRAKSVLKKLRGTADVTHDLQEMKEES 248
Query: 319 PQTMEEKKEIQNEPGIWSQVMRSPIIMKRLAICSWWWITCTFVFYGLAINSVSLAGDKYT 378
Q M EKK E S R PI++ + S VFY + + AG +
Sbjct: 249 RQMMREKKVTILEL-FRSPAYRQPILIAVVLQLSQQLSGINAVFY-YSTSIFEKAGVQQP 306
Query: 379 NYML--XXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAI 421
Y ++ V++R GR+ LIG + G++ CAI
Sbjct: 307 VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIG--LAGMAGCAI 349
>BC128580-1|AAI28581.1| 405|Homo sapiens C6orf85 protein protein.
Length = 405
Score = 45.2 bits (102), Expect = 6e-04
Identities = 27/91 (29%), Positives = 38/91 (41%)
Query: 194 MYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQY 253
M+ + F E A Y L IEL KR + T V G +A +
Sbjct: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60
Query: 254 WRTFILVVYPPALLFLSYIYFLPESIRWLLS 284
W+ ++ P LL L Y PES+RWL++
Sbjct: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMA 91
>BC036796-1|AAH36796.1| 340|Homo sapiens SVOP-like protein.
Length = 340
Score = 43.6 bits (98), Expect = 0.002
Identities = 56/253 (22%), Positives = 99/253 (39%), Gaps = 30/253 (11%)
Query: 254 WRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXX 313
WR I V P ++ + F+PES R+ +S MN
Sbjct: 49 WRWLIRVASIPGIILIVAFKFIPESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVE 108
Query: 314 XXXDKP---QTMEEKKEIQNEPGIW-----------SQVMRSPIIMKRLAICSWWWITCT 359
+K + + K ++ IW ++ S +++R +C +
Sbjct: 109 PVLEKRGRFADLLDAKYLRTTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAV 168
Query: 360 FVFYGLAINSVS------LAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMV 413
V G + S S A Y ++ +N L ++ +GR+ SL I
Sbjct: 169 VVTGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSIT--- 225
Query: 414 CGVSCCAIPFVRNHIVWLSI----FLYLLGKVAITQAFNGIYMYTSELFPTRARHSLLAF 469
+ C A+ F+ +I S FL++L + + FN +Y+YT+E++PT R +
Sbjct: 226 --MGCTALFFLLLNICTSSAGLIGFLFML-RALVAANFNTVYIYTAEVYPTTMRALGMGT 282
Query: 470 CSMVGRIGSIVAP 482
+ RIG++VAP
Sbjct: 283 SGSLCRIGAMVAP 295
>M91463-1|AAA52569.1| 505|Homo sapiens glucose transporter protein.
Length = 505
Score = 43.2 bits (97), Expect = 0.002
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 6/141 (4%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAF---SVSYEMYVIVEFL-E 202
I ++G ++S ++G IS GRK A++++ L + G+L + SYEM ++ FL
Sbjct: 87 IFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIG 146
Query: 203 TIAGASTFPASYILTIELLGQDKRVLTTAF-LGIVISMGGVCFALMAKTFQYWRTFILVV 261
+G I L G + A +GI+I+ +L+ T W + +
Sbjct: 147 AYSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG-TASLWPLLLGLT 205
Query: 262 YPPALLFLSYIYFLPESIRWL 282
PALL L + F PES R+L
Sbjct: 206 VLPALLQLVLLPFCPESPRYL 226
>AK075127-1|BAC11419.1| 248|Homo sapiens protein ( Homo sapiens
cDNA FLJ90646 fis, clone PLACE1004279. ).
Length = 248
Score = 41.9 bits (94), Expect = 0.006
Identities = 23/77 (29%), Positives = 33/77 (42%)
Query: 207 ASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPAL 266
A F +S L +E +R +T +G S G +A + WRT L P
Sbjct: 2 AGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFF 61
Query: 267 LFLSYIYFLPESIRWLL 283
++LPES RWL+
Sbjct: 62 AISLISWWLPESARWLI 78
>AB028977-1|BAA83006.1| 480|Homo sapiens KIAA1054 protein protein.
Length = 480
Score = 41.1 bits (92), Expect = 0.010
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Query: 393 INALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLYLLGKVAITQAFNGIYM 452
++AL++DRIGR L ++ G+SC + F + + + + L L + I+ A+N + +
Sbjct: 352 VSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGM-LCLYNGLTIS-AWNSLDV 409
Query: 453 YTSELFPTRARHS----LLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALVAG 507
T EL+PT R + L A C +G+++ + + K +P +L T LV G
Sbjct: 410 VTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSI---TKSIP-ILLASTVLVCG 464
Score = 31.9 bits (69), Expect = 6.0
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 227 VLTTAFLGIVISMGGVCFAL-MAKTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLL 283
+ +A +I G F++ A F WR F++V P + + + F+PES R+LL
Sbjct: 44 IYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLL 101
>AL445309-7|CAI40960.1| 175|Homo sapiens chromosome 6 open reading
frame 85 protein.
Length = 175
Score = 39.9 bits (89), Expect = 0.023
Identities = 27/100 (27%), Positives = 39/100 (39%)
Query: 172 LILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTA 231
L+ S + + G A SV+ M+ + F E A Y L IEL KR + T
Sbjct: 74 LLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITM 133
Query: 232 FLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSY 271
V G +A + W+ ++ P LL L Y
Sbjct: 134 VASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLY 173
>AL160398-2|CAI12304.1| 175|Homo sapiens chromosome 6 open reading
frame 85 protein.
Length = 175
Score = 39.9 bits (89), Expect = 0.023
Identities = 27/100 (27%), Positives = 39/100 (39%)
Query: 172 LILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTA 231
L+ S + + G A SV+ M+ + F E A Y L IEL KR + T
Sbjct: 74 LLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITM 133
Query: 232 FLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSY 271
V G +A + W+ ++ P LL L Y
Sbjct: 134 VASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLY 173
>AL110245-1|CAB53695.1| 175|Homo sapiens hypothetical protein
protein.
Length = 175
Score = 39.9 bits (89), Expect = 0.023
Identities = 27/100 (27%), Positives = 39/100 (39%)
Query: 172 LILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTA 231
L+ S + + G A SV+ M+ + F E A Y L IEL KR + T
Sbjct: 74 LLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITM 133
Query: 232 FLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSY 271
V G +A + W+ ++ P LL L Y
Sbjct: 134 VASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLY 173
>M20747-1|AAA59189.1| 509|Homo sapiens GLUT4 protein.
Length = 509
Score = 39.5 bits (88), Expect = 0.030
Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAF---SVSYEMYVIVEFL-- 201
I ++G ++S ++G IS GRK A++++ L + G+L + SYEM ++ FL
Sbjct: 87 IFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIG 146
Query: 202 ---ETIAGASTFPASYILTIELLGQDKRVLTTAF-LGIVISMGGVCFALMAKTFQYWRTF 257
+G I L G + A +GI+I+ +L+ T W
Sbjct: 147 AYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG-TASLWPLL 205
Query: 258 ILVVYPPALLFLSYIYFLPESIRWL 282
+ + PALL L + F PES R+L
Sbjct: 206 LGLTVLPALLQLVLLPFCPESPRYL 230
>BC126164-1|AAI26165.1| 509|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 4 protein.
Length = 509
Score = 39.5 bits (88), Expect = 0.030
Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAF---SVSYEMYVIVEFL-- 201
I ++G ++S ++G IS GRK A++++ L + G+L + SYEM ++ FL
Sbjct: 87 IFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIG 146
Query: 202 ---ETIAGASTFPASYILTIELLGQDKRVLTTAF-LGIVISMGGVCFALMAKTFQYWRTF 257
+G I L G + A +GI+I+ +L+ T W
Sbjct: 147 AYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG-TASLWPLL 205
Query: 258 ILVVYPPALLFLSYIYFLPESIRWL 282
+ + PALL L + F PES R+L
Sbjct: 206 LGLTVLPALLQLVLLPFCPESPRYL 230
>BC113592-1|AAI13593.1| 509|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 4 protein.
Length = 509
Score = 39.5 bits (88), Expect = 0.030
Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAF---SVSYEMYVIVEFL-- 201
I ++G ++S ++G IS GRK A++++ L + G+L + SYEM ++ FL
Sbjct: 87 IFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIG 146
Query: 202 ---ETIAGASTFPASYILTIELLGQDKRVLTTAF-LGIVISMGGVCFALMAKTFQYWRTF 257
+G I L G + A +GI+I+ +L+ T W
Sbjct: 147 AYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG-TASLWPLL 205
Query: 258 ILVVYPPALLFLSYIYFLPESIRWL 282
+ + PALL L + F PES R+L
Sbjct: 206 LGLTVLPALLQLVLLPFCPESPRYL 230
>BC069621-1|AAH69621.1| 509|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 4 protein.
Length = 509
Score = 39.5 bits (88), Expect = 0.030
Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAF---SVSYEMYVIVEFL-- 201
I ++G ++S ++G IS GRK A++++ L + G+L + SYEM ++ FL
Sbjct: 87 IFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIG 146
Query: 202 ---ETIAGASTFPASYILTIELLGQDKRVLTTAF-LGIVISMGGVCFALMAKTFQYWRTF 257
+G I L G + A +GI+I+ +L+ T W
Sbjct: 147 AYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG-TASLWPLL 205
Query: 258 ILVVYPPALLFLSYIYFLPESIRWL 282
+ + PALL L + F PES R+L
Sbjct: 206 LGLTVLPALLQLVLLPFCPESPRYL 230
>BC069615-1|AAH69615.1| 509|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 4 protein.
Length = 509
Score = 39.5 bits (88), Expect = 0.030
Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAF---SVSYEMYVIVEFL-- 201
I ++G ++S ++G IS GRK A++++ L + G+L + SYEM ++ FL
Sbjct: 87 IFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIG 146
Query: 202 ---ETIAGASTFPASYILTIELLGQDKRVLTTAF-LGIVISMGGVCFALMAKTFQYWRTF 257
+G I L G + A +GI+I+ +L+ T W
Sbjct: 147 AYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG-TASLWPLL 205
Query: 258 ILVVYPPALLFLSYIYFLPESIRWL 282
+ + PALL L + F PES R+L
Sbjct: 206 LGLTVLPALLQLVLLPFCPESPRYL 230
>BC034387-1|AAH34387.1| 415|Homo sapiens SLC2A4 protein protein.
Length = 415
Score = 39.5 bits (88), Expect = 0.030
Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 147 IHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAF---SVSYEMYVIVEFL-- 201
I ++G ++S ++G IS GRK A++++ L + G+L + SYEM ++ FL
Sbjct: 87 IFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIG 146
Query: 202 ---ETIAGASTFPASYILTIELLGQDKRVLTTAF-LGIVISMGGVCFALMAKTFQYWRTF 257
+G I L G + A +GI+I+ +L+ T W
Sbjct: 147 AYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG-TASLWPLL 205
Query: 258 ILVVYPPALLFLSYIYFLPESIRWL 282
+ + PALL L + F PES R+L
Sbjct: 206 LGLTVLPALLQLVLLPFCPESPRYL 230
>AJ243653-1|CAC01119.1| 366|Homo sapiens organic cation transporter
protein.
Length = 366
Score = 39.5 bits (88), Expect = 0.030
Identities = 58/298 (19%), Positives = 109/298 (36%), Gaps = 9/298 (3%)
Query: 214 YILTIELLGQDKRVLTTAFLGIVISMGG-VCFALMAKTFQYWRTFILVVYPPALLFLSYI 272
Y++ +EL +R L A G ++ +GG F +A + WR ++ P +LFL Y
Sbjct: 19 YLMRLELCDPTQR-LRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYG 77
Query: 273 Y--FLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEI-Q 329
+ ES RWL+ N + Q +E +
Sbjct: 78 WPGLFLESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLGEEAQEALQDLENTCPLPA 135
Query: 330 NEPGIWSQVMRSPIIMKRLAICSWW-WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXX 388
++ ++ I K L I + +I + D Y +L
Sbjct: 136 TSSSSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAA 195
Query: 389 XXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLY-LLGKVAITQAF 447
+ +DR GR+ LL+ + G++ + + +++ +I + +LG + A
Sbjct: 196 LACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAA 255
Query: 448 NGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALV 505
+ +E+ PT R L +G +G + P L + +L V+ AL+
Sbjct: 256 ILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALL 313
Score = 31.5 bits (68), Expect = 7.9
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 159 LGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTI 218
LG DRFGR+ L+LS TL G+ + Y + + S+ A+ + T+
Sbjct: 201 LGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTL 260
Query: 219 ELLGQDKRVLTTAFLGIVISMG--GVCFALMAKTFQYWRTFI--LVVYPPALLFLSYIYF 274
+ LG+++++G G + F+ +V+ ALL + I
Sbjct: 261 LAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIML 320
Query: 275 LPESIRWLL 283
LPE+ R LL
Sbjct: 321 LPETKRKLL 329
>AJ243122-1|CAC17762.1| 366|Homo sapiens organic cation transporter
protein.
Length = 366
Score = 39.1 bits (87), Expect = 0.040
Identities = 58/298 (19%), Positives = 109/298 (36%), Gaps = 9/298 (3%)
Query: 214 YILTIELLGQDKRVLTTAFLGIVISMGG-VCFALMAKTFQYWRTFILVVYPPALLFLSYI 272
Y++ +EL +R L A G ++ +GG F +A + WR ++ P +LFL Y
Sbjct: 19 YLMRLELCDPTQR-LRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYG 77
Query: 273 Y--FLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXXXXXXXXXXDKPQTMEEKKEIQN 330
+ ES RWL+ N + Q +E +
Sbjct: 78 WPGLFLESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLGEEAQEALQDLENTCPLPA 135
Query: 331 EPGI-WSQVMRSPIIMKRLAICSWW-WITCTFVFYGLAINSVSLAGDKYTNYMLXXXXXX 388
++ ++ I K L I + +I + D Y +L
Sbjct: 136 TSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAA 195
Query: 389 XXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIPFVRNHIVWLSIFLY-LLGKVAITQAF 447
+ +DR GR+ LL+ + G++ + + +++ +I + +LG + A
Sbjct: 196 LACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAA 255
Query: 448 NGIYMYTSELFPTRARHSLLAFCSMVGRIGSIVAPQMPLLEIYVKWLPSVLFGCTALV 505
+ +E+ PT R L +G +G + P L + +L V+ AL+
Sbjct: 256 ILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALL 313
Score = 31.5 bits (68), Expect = 7.9
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 159 LGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIVEFLETIAGASTFPASYILTI 218
LG DRFGR+ L+LS TL G+ + Y + + S+ A+ + T+
Sbjct: 201 LGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTL 260
Query: 219 ELLGQDKRVLTTAFLGIVISMG--GVCFALMAKTFQYWRTFI--LVVYPPALLFLSYIYF 274
+ LG+++++G G + F+ +V+ ALL + I
Sbjct: 261 LAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIML 320
Query: 275 LPESIRWLL 283
LPE+ R LL
Sbjct: 321 LPETKRKLL 329
>Y17801-1|CAB89809.1| 477|Homo sapiens glucose transporter 8
protein.
Length = 477
Score = 37.9 bits (84), Expect = 0.091
Identities = 36/144 (25%), Positives = 76/144 (52%), Gaps = 9/144 (6%)
Query: 145 GTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIV--EFLE 202
G + +G + G++ DR GRK++L+L C++ V G + + ++++++ L
Sbjct: 73 GAVVTLGAAAGGVLGGWLVDRAGRKLSLLL-CSVPFVAG-FAVITAAQDVWMLLGGRLLT 130
Query: 203 TIA-GASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTF-ILV 260
+A G ++ A ++ E+ R L + + +++ +G + A +A WR +L
Sbjct: 131 GLACGVASLVAPVYIS-EIAYPAVRGLLGSCVQLMVVVG-ILLAYLAGWVLEWRWLAVLG 188
Query: 261 VYPPALLFLSYIYFLPESIRWLLS 284
PP+L+ L + F+PE+ R+LL+
Sbjct: 189 CVPPSLMLL-LMCFMPETPRFLLT 211
>BC019043-1|AAH19043.1| 477|Homo sapiens solute carrier family 2,
(facilitated glucose transporter) member 8 protein.
Length = 477
Score = 37.9 bits (84), Expect = 0.091
Identities = 36/144 (25%), Positives = 76/144 (52%), Gaps = 9/144 (6%)
Query: 145 GTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIV--EFLE 202
G + +G + G++ DR GRK++L+L C++ V G + + ++++++ L
Sbjct: 73 GAVVTLGAAAGGVLGGWLVDRAGRKLSLLL-CSVPFVAG-FAVITAAQDVWMLLGGRLLT 130
Query: 203 TIA-GASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTF-ILV 260
+A G ++ A ++ E+ R L + + +++ +G + A +A WR +L
Sbjct: 131 GLACGVASLVAPVYIS-EIAYPAVRGLLGSCVQLMVVVG-ILLAYLAGWVLEWRWLAVLG 188
Query: 261 VYPPALLFLSYIYFLPESIRWLLS 284
PP+L+ L + F+PE+ R+LL+
Sbjct: 189 CVPPSLMLL-LMCFMPETPRFLLT 211
>BC012014-1|AAH12014.1| 177|Homo sapiens SLC22A16 protein protein.
Length = 177
Score = 37.9 bits (84), Expect = 0.091
Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 7/96 (7%)
Query: 76 DFNPVWLPNAAVEGQGERCSR-RVPLTQPCSADTSFSQEALAC-DHWIYANN---NTIVA 130
D+ V L N + + RCSR + T + + S++ C D +IY N +T V
Sbjct: 83 DYVTVQLQNGEI-WELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVT 141
Query: 131 EFNLAC-QEWKRTLVGTIHNIGMLVSLPILGYISDR 165
++NL C ++W L+ + G+L+ GY SDR
Sbjct: 142 QWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDR 177
>AL445309-8|CAI40961.1| 381|Homo sapiens chromosome 6 open reading
frame 85 protein.
Length = 381
Score = 37.9 bits (84), Expect = 0.091
Identities = 21/67 (31%), Positives = 30/67 (44%)
Query: 218 IELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTFILVVYPPALLFLSYIYFLPE 277
IEL KR + T V G +A + W+ ++ P LL L Y PE
Sbjct: 1 IELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPE 60
Query: 278 SIRWLLS 284
S+RWL++
Sbjct: 61 SLRWLMA 67
>AL445222-5|CAH72918.1| 477|Homo sapiens solute carrier family 2,
(facilitated glucose transporter) member 8 protein.
Length = 477
Score = 37.9 bits (84), Expect = 0.091
Identities = 36/144 (25%), Positives = 76/144 (52%), Gaps = 9/144 (6%)
Query: 145 GTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIV--EFLE 202
G + +G + G++ DR GRK++L+L C++ V G + + ++++++ L
Sbjct: 73 GAVVTLGAAAGGVLGGWLVDRAGRKLSLLL-CSVPFVAG-FAVITAAQDVWMLLGGRLLT 130
Query: 203 TIA-GASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTF-ILV 260
+A G ++ A ++ E+ R L + + +++ +G + A +A WR +L
Sbjct: 131 GLACGVASLVAPVYIS-EIAYPAVRGLLGSCVQLMVVVG-ILLAYLAGWVLEWRWLAVLG 188
Query: 261 VYPPALLFLSYIYFLPESIRWLLS 284
PP+L+ L + F+PE+ R+LL+
Sbjct: 189 CVPPSLMLL-LMCFMPETPRFLLT 211
>AL445222-4|CAH72917.1| 411|Homo sapiens solute carrier family 2,
(facilitated glucose transporter) member 8 protein.
Length = 411
Score = 37.9 bits (84), Expect = 0.091
Identities = 36/144 (25%), Positives = 76/144 (52%), Gaps = 9/144 (6%)
Query: 145 GTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIV--EFLE 202
G + +G + G++ DR GRK++L+L C++ V G + + ++++++ L
Sbjct: 73 GAVVTLGAAAGGVLGGWLVDRAGRKLSLLL-CSVPFVAG-FAVITAAQDVWMLLGGRLLT 130
Query: 203 TIA-GASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTF-ILV 260
+A G ++ A ++ E+ R L + + +++ +G + A +A WR +L
Sbjct: 131 GLACGVASLVAPVYIS-EIAYPAVRGLLGSCVQLMVVVG-ILLAYLAGWVLEWRWLAVLG 188
Query: 261 VYPPALLFLSYIYFLPESIRWLLS 284
PP+L+ L + F+PE+ R+LL+
Sbjct: 189 CVPPSLMLL-LMCFMPETPRFLLT 211
>AJ245937-1|CAB75702.1| 477|Homo sapiens glucose transporter
protein.
Length = 477
Score = 37.9 bits (84), Expect = 0.091
Identities = 36/144 (25%), Positives = 76/144 (52%), Gaps = 9/144 (6%)
Query: 145 GTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYVIV--EFLE 202
G + +G + G++ DR GRK++L+L C++ V G + + ++++++ L
Sbjct: 73 GAVVTLGAAAGGVLGGWLVDRAGRKLSLLL-CSVPFVAG-FAVITAAQDVWMLLGGRLLT 130
Query: 203 TIA-GASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKTFQYWRTF-ILV 260
+A G ++ A ++ E+ R L + + +++ +G + A +A WR +L
Sbjct: 131 GLACGVASLVAPVYIS-EIAYPAVRGLLGSCVQLMVVVG-ILLAYLAGWVLEWRWLAVLG 188
Query: 261 VYPPALLFLSYIYFLPESIRWLLS 284
PP+L+ L + F+PE+ R+LL+
Sbjct: 189 CVPPSLMLL-LMCFMPETPRFLLT 211
>BC113423-1|AAI13424.1| 541|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 10 protein.
Length = 541
Score = 36.7 bits (81), Expect = 0.21
Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 8/151 (5%)
Query: 131 EFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLK-AFS 189
+F L+C E + LVG++ +G L++ + G++ D +GRK A IL LV + G+L +
Sbjct: 39 DFGLSCLE-QEFLVGSLL-LGALLASLVGGFLIDCYGRKQA-ILGSNLVLLAGSLTLGLA 95
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMG-GVCFAL-- 246
S V+ + A + + A I EL+G +R + + I++G + +AL
Sbjct: 96 GSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY 155
Query: 247 -MAKTFQYWRTFILVVYPPALLFLSYIYFLP 276
+A T WR PA+L + FLP
Sbjct: 156 ALAGTPWGWRHMFGWATAPAVLQSLSLLFLP 186
>BC101657-1|AAI01658.1| 541|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 10 protein.
Length = 541
Score = 36.7 bits (81), Expect = 0.21
Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 8/151 (5%)
Query: 131 EFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLK-AFS 189
+F L+C E + LVG++ +G L++ + G++ D +GRK A IL LV + G+L +
Sbjct: 39 DFGLSCLE-QEFLVGSLL-LGALLASLVGGFLIDCYGRKQA-ILGSNLVLLAGSLTLGLA 95
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMG-GVCFAL-- 246
S V+ + A + + A I EL+G +R + + I++G + +AL
Sbjct: 96 GSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY 155
Query: 247 -MAKTFQYWRTFILVVYPPALLFLSYIYFLP 276
+A T WR PA+L + FLP
Sbjct: 156 ALAGTPWGWRHMFGWATAPAVLQSLSLLFLP 186
>AL137188-1|CAB69822.2| 541|Homo sapiens hypothetical protein
protein.
Length = 541
Score = 36.7 bits (81), Expect = 0.21
Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 8/151 (5%)
Query: 131 EFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLK-AFS 189
+F L+C E + LVG++ +G L++ + G++ D +GRK A IL LV + G+L +
Sbjct: 39 DFGLSCLE-QEFLVGSLL-LGALLASLVGGFLIDCYGRKQA-ILGSNLVLLAGSLTLGLA 95
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMG-GVCFAL-- 246
S V+ + A + + A I EL+G +R + + I++G + +AL
Sbjct: 96 GSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY 155
Query: 247 -MAKTFQYWRTFILVVYPPALLFLSYIYFLP 276
+A T WR PA+L + FLP
Sbjct: 156 ALAGTPWGWRHMFGWATAPAVLQSLSLLFLP 186
>AL031055-3|CAA19926.2| 541|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 10 protein.
Length = 541
Score = 36.7 bits (81), Expect = 0.21
Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 8/151 (5%)
Query: 131 EFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLK-AFS 189
+F L+C E + LVG++ +G L++ + G++ D +GRK A IL LV + G+L +
Sbjct: 39 DFGLSCLE-QEFLVGSLL-LGALLASLVGGFLIDCYGRKQA-ILGSNLVLLAGSLTLGLA 95
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMG-GVCFAL-- 246
S V+ + A + + A I EL+G +R + + I++G + +AL
Sbjct: 96 GSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY 155
Query: 247 -MAKTFQYWRTFILVVYPPALLFLSYIYFLP 276
+A T WR PA+L + FLP
Sbjct: 156 ALAGTPWGWRHMFGWATAPAVLQSLSLLFLP 186
>AF321240-1|AAK26294.1| 541|Homo sapiens facilitative glucose
transporter GLUT10 protein.
Length = 541
Score = 36.7 bits (81), Expect = 0.21
Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 8/151 (5%)
Query: 131 EFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLK-AFS 189
+F L+C E + LVG++ +G L++ + G++ D +GRK A IL LV + G+L +
Sbjct: 39 DFGLSCLE-QEFLVGSLL-LGALLASLVGGFLIDCYGRKQA-ILGSNLVLLAGSLTLGLA 95
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMG-GVCFAL-- 246
S V+ + A + + A I EL+G +R + + I++G + +AL
Sbjct: 96 GSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY 155
Query: 247 -MAKTFQYWRTFILVVYPPALLFLSYIYFLP 276
+A T WR PA+L + FLP
Sbjct: 156 ALAGTPWGWRHMFGWATAPAVLQSLSLLFLP 186
>AF248053-1|AAK31911.1| 541|Homo sapiens glucose transporter
protein.
Length = 541
Score = 36.7 bits (81), Expect = 0.21
Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 8/151 (5%)
Query: 131 EFNLACQEWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLK-AFS 189
+F L+C E + LVG++ +G L++ + G++ D +GRK A IL LV + G+L +
Sbjct: 39 DFGLSCLE-QEFLVGSLL-LGALLASLVGGFLIDCYGRKQA-ILGSNLVLLAGSLTLGLA 95
Query: 190 VSYEMYVIVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMG-GVCFAL-- 246
S V+ + A + + A I EL+G +R + + I++G + +AL
Sbjct: 96 GSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY 155
Query: 247 -MAKTFQYWRTFILVVYPPALLFLSYIYFLP 276
+A T WR PA+L + FLP
Sbjct: 156 ALAGTPWGWRHMFGWATAPAVLQSLSLLFLP 186
>BC110414-1|AAI10415.1| 540|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 9 protein.
Length = 540
Score = 35.5 bits (78), Expect = 0.49
Identities = 81/349 (23%), Positives = 138/349 (39%), Gaps = 35/349 (10%)
Query: 139 WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV---SYEMY 195
W T+ +I IG LV I+ I GRK L+ + L A S+ ++EM
Sbjct: 110 WSVTV--SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEML 167
Query: 196 VIVEFLETIAGA---STFPA--SYILTIELLGQDKRVLTTAFLGIVISMGGVCFA--LMA 248
++ F+ I G S P S I E+ G +V T F+ I + G + L+
Sbjct: 168 IVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQV-TAIFICIGVFTGQLLGLPELLG 226
Query: 249 KTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXX 308
K W V+ PA++ L + FLP+S R+LL +
Sbjct: 227 KE-STWPYLFGVIVVPAVVQLLSLPFLPDSPRYLL-LEKHNEARAVKAFQTFLGKADVSQ 284
Query: 309 XXXXXXXXDKPQ---TMEEKKEIQNEPGIWSQVMRSPIIMKRLAIC---SWWWITCTFVF 362
+ Q + E+ P + QV+ + M +C + W+ T +
Sbjct: 285 EVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNS--I 342
Query: 363 YGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIP 422
+G A + LA Y + + LV++ +GR+ L+ GF + G+ +
Sbjct: 343 FGKA--GIPLAKIPYVT-LSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLT 399
Query: 423 F---VRNHIVWLSIFLYLLGKVAITQAF----NGI-YMYTSELFPTRAR 463
+++H W+ +L ++G +AI +F GI ++ T E F R
Sbjct: 400 ITLTLQDHAPWVP-YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQR 447
>BC018897-1|AAH18897.1| 511|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 9 protein.
Length = 511
Score = 35.5 bits (78), Expect = 0.49
Identities = 81/349 (23%), Positives = 138/349 (39%), Gaps = 35/349 (10%)
Query: 139 WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV---SYEMY 195
W T+ +I IG LV I+ I GRK L+ + L A S+ ++EM
Sbjct: 81 WSVTV--SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEML 138
Query: 196 VIVEFLETIAGA---STFPA--SYILTIELLGQDKRVLTTAFLGIVISMGGVCFA--LMA 248
++ F+ I G S P S I E+ G +V T F+ I + G + L+
Sbjct: 139 IVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQV-TAIFICIGVFTGQLLGLPELLG 197
Query: 249 KTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXX 308
K W V+ PA++ L + FLP+S R+LL +
Sbjct: 198 KE-STWPYLFGVIVVPAVVQLLSLPFLPDSPRYLL-LEKHNEARAVKAFQTFLGKADVSQ 255
Query: 309 XXXXXXXXDKPQ---TMEEKKEIQNEPGIWSQVMRSPIIMKRLAIC---SWWWITCTFVF 362
+ Q + E+ P + QV+ + M +C + W+ T +
Sbjct: 256 EVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNS--I 313
Query: 363 YGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIP 422
+G A + LA Y + + LV++ +GR+ L+ GF + G+ +
Sbjct: 314 FGKA--GIPLAKIPYVT-LSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLT 370
Query: 423 F---VRNHIVWLSIFLYLLGKVAITQAF----NGI-YMYTSELFPTRAR 463
+++H W+ +L ++G +AI +F GI ++ T E F R
Sbjct: 371 ITLTLQDHAPWVP-YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQR 418
>AF210317-1|AAF85942.1| 540|Homo sapiens facilitative glucose
transporter family member GLUT9 protein.
Length = 540
Score = 35.5 bits (78), Expect = 0.49
Identities = 81/349 (23%), Positives = 138/349 (39%), Gaps = 35/349 (10%)
Query: 139 WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV---SYEMY 195
W T+ +I IG LV I+ I GRK L+ + L A S+ ++EM
Sbjct: 110 WSVTV--SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEML 167
Query: 196 VIVEFLETIAGA---STFPA--SYILTIELLGQDKRVLTTAFLGIVISMGGVCFA--LMA 248
++ F+ I G S P S I E+ G +V T F+ I + G + L+
Sbjct: 168 IVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQV-TAIFICIGVFTGQLLGLPELLG 226
Query: 249 KTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLLSXXXXXXXXXXXXXXXXMNNVXXXX 308
K W V+ PA++ L + FLP+S R+LL +
Sbjct: 227 KE-STWPYLFGVIVVPAVVQLLSLPFLPDSPRYLL-LEKHNEARAVKAFQTFLGKADVSQ 284
Query: 309 XXXXXXXXDKPQ---TMEEKKEIQNEPGIWSQVMRSPIIMKRLAIC---SWWWITCTFVF 362
+ Q + E+ P + QV+ + M +C + W+ T +
Sbjct: 285 EVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNS--I 342
Query: 363 YGLAINSVSLAGDKYTNYMLXXXXXXXXXXINALVLDRIGRKRSLLIGFMVCGVSCCAIP 422
+G A + LA Y + + LV++ +GR+ L+ GF + G+ +
Sbjct: 343 FGKA--GIPLAKIPYVT-LSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLT 399
Query: 423 F---VRNHIVWLSIFLYLLGKVAITQAF----NGI-YMYTSELFPTRAR 463
+++H W+ +L ++G +AI +F GI ++ T E F R
Sbjct: 400 ITLTLQDHAPWVP-YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQR 447
>BC036662-1|AAH36662.1| 461|Homo sapiens solute carrier family 46,
member 3 protein.
Length = 461
Score = 35.1 bits (77), Expect = 0.64
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 153 LVSLPILGYISDRFGRKVALILSCTLVGVIGT------LKAFSVSYEMYVIVEFLETIAG 206
LVS IL ISD +GRK +ILS VG + T L F+ +++ + F+ G
Sbjct: 85 LVSTFILLSISDHYGRKFPMILSS--VGALATSVWLCLLCYFAFPFQLLIASTFIGAFCG 142
Query: 207 AST--FPASYILTIELLGQDK----RVLTTAF-LGIVISMGGVCFALMAKTFQYWRTFIL 259
T + A + ++ + K R+ F LG+V + G+ + + +F++
Sbjct: 143 NYTTFWGACFAYIVDQFKEHKQKTIRIAIIDFLLGLVTGLTGLSSGYFIRELGFEWSFLI 202
Query: 260 VVYPPALLFLSYIYFLPESIR 280
+ A+ + ++FL + ++
Sbjct: 203 IAVSLAVNLIYILFFLGDPVK 223
>BX537565-1|CAD97783.1| 461|Homo sapiens hypothetical protein
protein.
Length = 461
Score = 34.7 bits (76), Expect = 0.85
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 153 LVSLPILGYISDRFGRKVALILSCTLVGVIGT------LKAFSVSYEMYVIVEFLETIAG 206
LVS IL ISD +GRK +ILS VG + T L F+ +++ + F+ G
Sbjct: 85 LVSTFILLSISDHYGRKFPMILSS--VGALATSVWLCLLCYFAFPFQLLIASTFIGAFCG 142
Query: 207 AST--FPASYILTIELLGQDK----RVLTTAF-LGIVISMGGVCFALMAKTFQYWRTFIL 259
T + A + ++ + K R+ F LG+V + G+ + + +F++
Sbjct: 143 NYTTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTGLSSGYFIRELGFEWSFLI 202
Query: 260 VVYPPALLFLSYIYFLPESIR 280
+ A+ + ++FL + ++
Sbjct: 203 IAVSLAVNLIYILFFLGDPVK 223
>BC060850-1|AAH60850.1| 463|Homo sapiens SLC46A3 protein protein.
Length = 463
Score = 34.7 bits (76), Expect = 0.85
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 153 LVSLPILGYISDRFGRKVALILSCTLVGVIGT------LKAFSVSYEMYVIVEFLETIAG 206
LVS IL ISD +GRK +ILS VG + T L F+ +++ + F+ G
Sbjct: 85 LVSTFILLSISDHYGRKFPMILSS--VGALATSVWLCLLCYFAFPFQLLIASTFIGAFCG 142
Query: 207 AST--FPASYILTIELLGQDK----RVLTTAF-LGIVISMGGVCFALMAKTFQYWRTFIL 259
T + A + ++ + K R+ F LG+V + G+ + + +F++
Sbjct: 143 NYTTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTGLSSGYFIRELGFEWSFLI 202
Query: 260 VVYPPALLFLSYIYFLPESIR 280
+ A+ + ++FL + ++
Sbjct: 203 IAVSLAVNLIYILFFLGDPVK 223
>AL359454-3|CAM24029.1| 461|Homo sapiens novel protein protein.
Length = 461
Score = 34.7 bits (76), Expect = 0.85
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 153 LVSLPILGYISDRFGRKVALILSCTLVGVIGT------LKAFSVSYEMYVIVEFLETIAG 206
LVS IL ISD +GRK +ILS VG + T L F+ +++ + F+ G
Sbjct: 85 LVSTFILLSISDHYGRKFPMILSS--VGALATSVWLCLLCYFAFPFQLLIASTFIGAFCG 142
Query: 207 AST--FPASYILTIELLGQDK----RVLTTAF-LGIVISMGGVCFALMAKTFQYWRTFIL 259
T + A + ++ + K R+ F LG+V + G+ + + +F++
Sbjct: 143 NYTTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTGLSSGYFIRELGFEWSFLI 202
Query: 260 VVYPPALLFLSYIYFLPESIR 280
+ A+ + ++FL + ++
Sbjct: 203 IAVSLAVNLIYILFFLGDPVK 223
>AL359454-2|CAI17158.1| 463|Homo sapiens novel protein protein.
Length = 463
Score = 34.7 bits (76), Expect = 0.85
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 153 LVSLPILGYISDRFGRKVALILSCTLVGVIGT------LKAFSVSYEMYVIVEFLETIAG 206
LVS IL ISD +GRK +ILS VG + T L F+ +++ + F+ G
Sbjct: 85 LVSTFILLSISDHYGRKFPMILSS--VGALATSVWLCLLCYFAFPFQLLIASTFIGAFCG 142
Query: 207 AST--FPASYILTIELLGQDK----RVLTTAF-LGIVISMGGVCFALMAKTFQYWRTFIL 259
T + A + ++ + K R+ F LG+V + G+ + + +F++
Sbjct: 143 NYTTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTGLSSGYFIRELGFEWSFLI 202
Query: 260 VVYPPALLFLSYIYFLPESIR 280
+ A+ + ++FL + ++
Sbjct: 203 IAVSLAVNLIYILFFLGDPVK 223
>AK124604-1|BAC85896.1| 304|Homo sapiens protein ( Homo sapiens
cDNA FLJ42613 fis, clone BRACE3014005. ).
Length = 304
Score = 34.7 bits (76), Expect = 0.85
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 153 LVSLPILGYISDRFGRKVALILSCTLVGVIGT------LKAFSVSYEMYVIVEFLETIAG 206
LVS IL ISD +GRK +ILS VG + T L F+ +++ + F+ G
Sbjct: 10 LVSTFILLSISDHYGRKFPMILSS--VGALATSVWLCLLCYFAFPFQLLIASTFIGAFCG 67
Query: 207 AST--FPASYILTIELLGQDK----RVLTTAF-LGIVISMGGVCFALMAKTFQYWRTFIL 259
T + A + ++ + K R+ F LG+V + G+ + + +F++
Sbjct: 68 NYTTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTGLSSGYFIRELGFEWSFLI 127
Query: 260 VVYPPALLFLSYIYFLPESIR 280
+ A+ + ++FL + ++
Sbjct: 128 IAVSLAVNLIYILFFLGDPVK 148
>BC068556-1|AAH68556.1| 461|Homo sapiens solute carrier family 46,
member 3 protein.
Length = 461
Score = 34.3 bits (75), Expect = 1.1
Identities = 33/141 (23%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 153 LVSLPILGYISDRFGRKVALILSCTLVGVIGT------LKAFSVSYEMYVIVEFLETIAG 206
LVS IL ISD +GRK +ILS +G + T L F+ +++ + F+ G
Sbjct: 85 LVSTFILLSISDHYGRKFPMILSS--IGALATSVWLCLLCYFAFPFQLLIASTFIGAFCG 142
Query: 207 AST--FPASYILTIELLGQDK----RVLTTAF-LGIVISMGGVCFALMAKTFQYWRTFIL 259
T + A + ++ + K R+ F LG+V + G+ + + +F++
Sbjct: 143 NYTTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTGLSSGYFIRELGFEWSFLI 202
Query: 260 VVYPPALLFLSYIYFLPESIR 280
+ A+ + ++FL + ++
Sbjct: 203 IAVSLAVNLIYILFFLGDPVK 223
>BC041772-1|AAH41772.2| 549|Homo sapiens LOC124976 protein protein.
Length = 549
Score = 33.5 bits (73), Expect = 2.0
Identities = 16/34 (47%), Positives = 22/34 (64%), Gaps = 2/34 (5%)
Query: 143 LVGTIHNIGMLVSLPILGYISDRFGRKVALILSC 176
L+ ++ +V+ PI GY+ DRF RKV ILSC
Sbjct: 142 LLQSVFICSFMVAAPIFGYLGDRFNRKV--ILSC 173
>AJ315644-1|CAC51116.1| 629|Homo sapiens proton myo-inositol
transporter protein.
Length = 629
Score = 33.5 bits (73), Expect = 2.0
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 14/154 (9%)
Query: 139 WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYV-- 196
W+ LV + + +L G ++ FGR+ A++L+ L + A + + E +
Sbjct: 100 WQELLVSSTVGAAAVSALAG-GALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAG 158
Query: 197 -IVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK-TFQY- 253
+V L + T P YI + R++T L I GG FA + F Y
Sbjct: 159 RLVVGLGIGIASMTVPV-YIAEVSPPNLRGRLVTINTLFIT---GGQFFASVVDGAFSYL 214
Query: 254 ----WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
WR + + PA++ FLPES RWL+
Sbjct: 215 QKDGWRYMLGLAXVPAVIQFFGFLFLPESPRWLI 248
>U79745-1|AAC52014.1| 523|Homo sapiens monocarboxylate transporter
homologue MCT6 protein.
Length = 523
Score = 33.1 bits (72), Expect = 2.6
Identities = 23/96 (23%), Positives = 48/96 (50%), Gaps = 9/96 (9%)
Query: 155 SLPILGYISDRFGRKVALILSCTLV--GVIGTLKAFSVSYEMYVIVEFLETIAGASTFPA 212
S P+ +S+RFG ++ ++L LV G++ + VS+ MYV + + + +F
Sbjct: 77 SAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSH-MYVAIGIISGLGYCFSFLP 135
Query: 213 SYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA 248
+ + + G+ + ++T ++ G CFA+ A
Sbjct: 136 TVTILSQYFGKRRSIVT------AVASTGECFAVFA 165
>BC117119-1|AAI17120.1| 629|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 13 protein.
Length = 629
Score = 33.1 bits (72), Expect = 2.6
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 14/154 (9%)
Query: 139 WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYV-- 196
W+ LV + + +L G ++ FGR+ A++L+ L + A + + E +
Sbjct: 100 WQELLVSSTVGAAAVSALAG-GALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAG 158
Query: 197 -IVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK-TFQY- 253
+V L + T P YI + R++T L I GG FA + F Y
Sbjct: 159 RLVVGLGIGIASMTVPV-YIAEVSPPNLRGRLVTINTLFIT---GGQFFASVVDGAFSYL 214
Query: 254 ----WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
WR + + PA++ FLPES RWL+
Sbjct: 215 QKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLI 248
>BC117117-1|AAI17118.1| 629|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 13 protein.
Length = 629
Score = 33.1 bits (72), Expect = 2.6
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 14/154 (9%)
Query: 139 WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYV-- 196
W+ LV + + +L G ++ FGR+ A++L+ L + A + + E +
Sbjct: 100 WQELLVSSTVGAAAVSALAG-GALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAG 158
Query: 197 -IVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK-TFQY- 253
+V L + T P YI + R++T L I GG FA + F Y
Sbjct: 159 RLVVGLGIGIASMTVPV-YIAEVSPPNLRGRLVTINTLFIT---GGQFFASVVDGAFSYL 214
Query: 254 ----WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
WR + + PA++ FLPES RWL+
Sbjct: 215 QKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLI 248
>BC064832-1|AAH64832.1| 523|Homo sapiens solute carrier family 16,
member 6 (monocarboxylic acid transporter 7) protein.
Length = 523
Score = 33.1 bits (72), Expect = 2.6
Identities = 23/96 (23%), Positives = 48/96 (50%), Gaps = 9/96 (9%)
Query: 155 SLPILGYISDRFGRKVALILSCTLV--GVIGTLKAFSVSYEMYVIVEFLETIAGASTFPA 212
S P+ +S+RFG ++ ++L LV G++ + VS+ MYV + + + +F
Sbjct: 77 SAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSH-MYVAIGIISGLGYCFSFLP 135
Query: 213 SYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMA 248
+ + + G+ + ++T ++ G CFA+ A
Sbjct: 136 TVTILSQYFGKRRSIVT------AVASTGECFAVFA 165
>BC047507-1|AAH47507.1| 338|Homo sapiens SLC2A13 protein protein.
Length = 338
Score = 33.1 bits (72), Expect = 2.6
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 14/154 (9%)
Query: 139 WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMYV-- 196
W+ LV + + +L G ++ FGR+ A++L+ L + A + + E +
Sbjct: 100 WQELLVSSTVGAAAVSALAG-GALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAG 158
Query: 197 -IVEFLETIAGASTFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAK-TFQY- 253
+V L + T P YI + R++T L I GG FA + F Y
Sbjct: 159 RLVVGLGIGIASMTVPV-YIAEVSPPNLRGRLVTINTLFIT---GGQFFASVVDGAFSYL 214
Query: 254 ----WRTFILVVYPPALLFLSYIYFLPESIRWLL 283
WR + + PA++ FLPES RWL+
Sbjct: 215 QKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLI 248
>BC015571-1|AAH15571.1| 424|Homo sapiens solute carrier family 22
(organic cation transporter), member 18 protein.
Length = 424
Score = 32.7 bits (71), Expect = 3.4
Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 146 TIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY-VIVEFLETI 204
T + L+ P+ G +D+ G + AL LS + L A + S + V + F +
Sbjct: 66 TTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRL 125
Query: 205 AGA--STFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
GA T PA+ ++ +L ++R LG+ +G + +L+ T
Sbjct: 126 PGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGT 173
>AF421859-1|AAL16939.1| 199|Homo sapiens solute carrier family 2
member 9 protein.
Length = 199
Score = 32.7 bits (71), Expect = 3.4
Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 14/155 (9%)
Query: 139 WKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSV---SYEMY 195
W T+ +I IG LV I+ I GRK L+ + L A S+ ++EM
Sbjct: 26 WSVTV--SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEML 83
Query: 196 VIVEFLETIAGA---STFPA--SYILTIELLGQDKRVLTTAFLGIVISMGGVCFA--LMA 248
++ F+ I G S P S I E+ G +V T F+ I + G + L+
Sbjct: 84 IVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQV-TAIFICIGVFTGQLLGLPELLG 142
Query: 249 KTFQYWRTFILVVYPPALLFLSYIYFLPESIRWLL 283
K W V+ PA++ L + FLP+S R+LL
Sbjct: 143 KE-STWPYLFGVIVVPAVVQLLSLPFLPDSPRYLL 176
>AF070479-1|AAC23505.1| 424|Homo sapiens efflux transporter like
protein protein.
Length = 424
Score = 32.7 bits (71), Expect = 3.4
Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 146 TIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY-VIVEFLETI 204
T + L+ P+ G +D+ G + AL LS + L A + S + V + F +
Sbjct: 66 TTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRL 125
Query: 205 AGA--STFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
GA T PA+ ++ +L ++R LG+ +G + +L+ T
Sbjct: 126 PGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGT 173
>AF059663-1|AAC14725.1| 424|Homo sapiens tumor suppressing STF cDNA
5 protein.
Length = 424
Score = 32.7 bits (71), Expect = 3.4
Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 146 TIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY-VIVEFLETI 204
T + L+ P+ G +D+ G + AL LS + L A + S + V + F +
Sbjct: 66 TTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRL 125
Query: 205 AGA--STFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
GA T PA+ ++ +L ++R LG+ +G + +L+ T
Sbjct: 126 PGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGT 173
>AF037064-1|AAC04787.1| 424|Homo sapiens organic cation
transporter-like protein 2 protein.
Length = 424
Score = 32.7 bits (71), Expect = 3.4
Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 146 TIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY-VIVEFLETI 204
T + L+ P+ G +D+ G + AL LS + L A + S + V + F +
Sbjct: 66 TTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRL 125
Query: 205 AGA--STFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
GA T PA+ ++ +L ++R LG+ +G + +L+ T
Sbjct: 126 PGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGT 173
>AF028738-1|AAB82727.1| 408|Homo sapiens imprinted multi-membrane
spanning polyspecific transporter-related protein
protein.
Length = 408
Score = 32.7 bits (71), Expect = 3.4
Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 146 TIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY-VIVEFLETI 204
T + L+ P+ G +D+ G + AL LS + L A + S + V + F +
Sbjct: 50 TTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRL 109
Query: 205 AGA--STFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
GA T PA+ ++ +L ++R LG+ +G + +L+ T
Sbjct: 110 PGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGT 157
>AB012083-1|BAA32779.1| 408|Homo sapiens ITM protein.
Length = 408
Score = 32.7 bits (71), Expect = 3.4
Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 146 TIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKAFSVSYEMY-VIVEFLETI 204
T + L+ P+ G +D+ G + AL LS + L A + S + V + F +
Sbjct: 50 TTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRL 109
Query: 205 AGA--STFPASYILTIELLGQDKRVLTTAFLGIVISMGGVCFALMAKT 250
GA T PA+ ++ +L ++R LG+ +G + +L+ T
Sbjct: 110 PGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGT 157
>DQ658848-1|ABG45942.1| 207|Homo sapiens esophageal carcinoma NGAL
receptor transcript variant 3 protein.
Length = 207
Score = 32.3 bits (70), Expect = 4.5
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 129 VAEFNLACQ-EWKRTLVGTIHNIGMLVSLPILGYISDRFGRKVALILSCTLVGVIGTLKA 187
+ +++L C W+ L + +G LGY +D FGR+ ++L+ LVG G A
Sbjct: 87 IGQWDLVCDLGWQVILGQILFILGFASGYLFLGYPADGFGRRGIVLLTLGLVGPCGVGGA 146
Query: 188 FSVSYEMYVIVEFL 201
+ S + + FL
Sbjct: 147 AAGSSTGVMALRFL 160
>AY571960-1|AAS78590.2| 512|Homo sapiens intestinal facilitative
glucose transporter 7 protein.
Length = 512
Score = 32.3 bits (70), Expect = 4.5
Identities = 11/31 (35%), Positives = 22/31 (70%)
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFV 424
+A++++R+GR+ LL G+ +CG +C + V
Sbjct: 338 SAVLVERLGRRHLLLAGYGICGSACLVLTVV 368
>AL158048-4|CAI23459.2| 524|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 7 protein.
Length = 524
Score = 32.3 bits (70), Expect = 4.5
Identities = 11/31 (35%), Positives = 22/31 (70%)
Query: 394 NALVLDRIGRKRSLLIGFMVCGVSCCAIPFV 424
+A++++R+GR+ LL G+ +CG +C + V
Sbjct: 350 SAVLVERLGRRHLLLAGYGICGSACLVLTVV 380
>U11843-1|AAB60641.1| 481|Homo sapiens fructose transporter
protein.
Length = 481
Score = 31.9 bits (69), Expect = 6.0
Identities = 10/25 (40%), Positives = 19/25 (76%)
Query: 397 VLDRIGRKRSLLIGFMVCGVSCCAI 421
V++ +GR+ LL+GF +C ++CC +
Sbjct: 315 VVELLGRRLLLLLGFSICLIACCVL 339
>M55531-1|AAA52570.1| 501|Homo sapiens GLUT5 protein protein.
Length = 501
Score = 31.9 bits (69), Expect = 6.0
Identities = 10/25 (40%), Positives = 19/25 (76%)
Query: 397 VLDRIGRKRSLLIGFMVCGVSCCAI 421
V++ +GR+ LL+GF +C ++CC +
Sbjct: 335 VVELLGRRLLLLLGFSICLIACCVL 359
>BC001820-1|AAH01820.1| 501|Homo sapiens solute carrier family 2
(facilitated glucose/fructose transporter), member 5
protein.
Length = 501
Score = 31.9 bits (69), Expect = 6.0
Identities = 10/25 (40%), Positives = 19/25 (76%)
Query: 397 VLDRIGRKRSLLIGFMVCGVSCCAI 421
V++ +GR+ LL+GF +C ++CC +
Sbjct: 335 VVELLGRRLLLLLGFSICLIACCVL 359
>BC001692-1|AAH01692.1| 501|Homo sapiens solute carrier family 2
(facilitated glucose/fructose transporter), member 5
protein.
Length = 501
Score = 31.9 bits (69), Expect = 6.0
Identities = 10/25 (40%), Positives = 19/25 (76%)
Query: 397 VLDRIGRKRSLLIGFMVCGVSCCAI 421
V++ +GR+ LL+GF +C ++CC +
Sbjct: 335 VVELLGRRLLLLLGFSICLIACCVL 359
>AL158048-3|CAI23458.1| 501|Homo sapiens solute carrier family 2
(facilitated glucose/fructose transporter), member 5
protein.
Length = 501
Score = 31.9 bits (69), Expect = 6.0
Identities = 10/25 (40%), Positives = 19/25 (76%)
Query: 397 VLDRIGRKRSLLIGFMVCGVSCCAI 421
V++ +GR+ LL+GF +C ++CC +
Sbjct: 335 VVELLGRRLLLLLGFSICLIACCVL 359
>BC131825-1|AAI31826.1| 479|Homo sapiens FLJ45557 protein protein.
Length = 479
Score = 31.5 bits (68), Expect = 7.9
Identities = 18/50 (36%), Positives = 22/50 (44%), Gaps = 3/50 (6%)
Query: 56 LAGSVPYRCTVPECESLNTTDFNPVWL---PNAAVEGQGERCSRRVPLTQ 102
LA S P +C PEC + P L P+ GE C R VP T+
Sbjct: 305 LACSPPMQCLSPECSEQPSQTHTPPGLGNQPSPTAVAAGEECQRIVPHTE 354
>BC057236-1|AAH57236.1| 270|Homo sapiens ATP8B4 protein protein.
Length = 270
Score = 31.5 bits (68), Expect = 7.9
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 423 FVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPT--RARHSLLAFCSMVGRIGSIV 480
F+ + +W SI +Y + T NGI+ FP ARHSL C + + + V
Sbjct: 97 FINHVFIWGSIAIYF--SILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTV 154
Query: 481 APQMPLL 487
A MP++
Sbjct: 155 ASVMPVV 161
>AK127465-1|BAC86991.1| 479|Homo sapiens protein ( Homo sapiens
cDNA FLJ45557 fis, clone BRTHA3002411. ).
Length = 479
Score = 31.5 bits (68), Expect = 7.9
Identities = 18/50 (36%), Positives = 22/50 (44%), Gaps = 3/50 (6%)
Query: 56 LAGSVPYRCTVPECESLNTTDFNPVWL---PNAAVEGQGERCSRRVPLTQ 102
LA S P +C PEC + P L P+ GE C R VP T+
Sbjct: 305 LACSPPMQCLSPECSEQPSQTHTPPGLGNQPSPTAVAAGEECQRIVPHTE 354
>AK025125-1|BAB15072.1| 195|Homo sapiens roto-LBC) mRNA. protein.
Length = 195
Score = 31.5 bits (68), Expect = 7.9
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 423 FVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPT--RARHSLLAFCSMVGRIGSIV 480
F+ + +W SI +Y + T NGI+ FP ARHSL C + + + V
Sbjct: 22 FINHVFIWGSIAIYF--SILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTV 79
Query: 481 APQMPLL 487
A MP++
Sbjct: 80 ASVMPVV 86
>AB075819-1|BAB85525.1| 1082|Homo sapiens KIAA1939 protein protein.
Length = 1082
Score = 31.5 bits (68), Expect = 7.9
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 423 FVRNHIVWLSIFLYLLGKVAITQAFNGIYMYTSELFPT--RARHSLLAFCSMVGRIGSIV 480
F+ + +W SI +Y + T NGI+ FP ARHSL C + + + V
Sbjct: 909 FINHVFIWGSIAIYF--SILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTV 966
Query: 481 APQMPLL 487
A MP++
Sbjct: 967 ASVMPVV 973
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.326 0.139 0.437
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 72,003,668
Number of Sequences: 224733
Number of extensions: 2625120
Number of successful extensions: 8763
Number of sequences better than 10.0: 195
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 8231
Number of HSP's gapped (non-prelim): 421
length of query: 549
length of database: 73,234,838
effective HSP length: 94
effective length of query: 455
effective length of database: 52,109,936
effective search space: 23710020880
effective search space used: 23710020880
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 68 (31.5 bits)
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