Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001291-TA|BGIBMGA001291-PA|IPR000917|Sulfatase
(508 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M58342-1|AAA63197.1| 550|Homo sapiens iduronate 2-sulfatase pro... 436 e-122
L13329-1|AAA16877.1| 550|Homo sapiens iduronate-2-sulfatase pro... 436 e-122
AF011889-1|AAC77828.1| 550|Homo sapiens iduronate 2-sulfatase p... 436 e-122
L04586-1|AAA59192.1| 398|Homo sapiens iduronate 2-sulfatase pro... 370 e-102
L40586-1|AAA92014.1| 343|Homo sapiens iduronate-2-sulphatase pr... 328 3e-89
BC006170-1|AAH06170.1| 312|Homo sapiens IDS protein protein. 289 1e-77
AF050145-1|AAC05984.1| 179|Homo sapiens iduronate-2-sulfatase p... 131 6e-30
L38660-1|AAB64180.1| 86|Homo sapiens iduronate-2-sulphatase pr... 118 5e-26
BC130329-1|AAI30330.1| 536|Homo sapiens arylsulfatase family, m... 86 3e-16
BC036047-1|AAH36047.1| 542|Homo sapiens ARSK protein protein. 86 3e-16
AY875939-1|AAW66667.1| 536|Homo sapiens arylsulfatase K protein. 86 3e-16
AY358596-1|AAQ88959.1| 536|Homo sapiens Bone Rel Sulphatase pro... 86 3e-16
AL832711-1|CAD38634.1| 483|Homo sapiens hypothetical protein pr... 84 1e-15
Z12173-1|CAA78164.1| 552|Homo sapiens N-acetylglucosamine-6-sul... 83 2e-15
BC012482-1|AAH12482.1| 552|Homo sapiens glucosamine (N-acetyl)-... 83 2e-15
AK223484-1|BAD97204.1| 552|Homo sapiens glucosamine (N-acetyl)-... 83 3e-15
BX537363-1|CAD97608.1| 496|Homo sapiens hypothetical protein pr... 81 9e-15
AY101175-1|AAM76860.1| 871|Homo sapiens extracellular sulfatase... 77 2e-13
AF545571-1|AAO33315.1| 871|Homo sapiens sulfatase SULF1 precurs... 74 1e-12
AB029000-1|BAA83029.1| 818|Homo sapiens KIAA1077 protein protein. 72 4e-12
BC110539-1|AAI10540.1| 870|Homo sapiens sulfatase 2 protein. 71 1e-11
AY358461-1|AAQ88826.1| 867|Homo sapiens GPPS559 protein. 71 1e-11
AY101176-1|AAM76861.1| 870|Homo sapiens extracellular sulfatase... 71 1e-11
AL354813-2|CAI17943.1| 870|Homo sapiens RP5-1049G16.1 protein. 71 1e-11
AL034418-7|CAI42143.1| 870|Homo sapiens RP5-1049G16.1 protein. 71 1e-11
AB033073-1|BAA86561.2| 885|Homo sapiens KIAA1247 protein protein. 69 3e-11
U06088-1|AAC51350.1| 522|Homo sapiens N-acetylgalactosamine 6-s... 56 2e-07
D17629-1|BAA04535.1| 522|Homo sapiens N-acetylgalactosamine 6-s... 56 2e-07
BC056151-1|AAH56151.1| 522|Homo sapiens galactosamine (N-acetyl... 56 2e-07
BC050684-1|AAH50684.2| 522|Homo sapiens galactosamine (N-acetyl... 56 2e-07
X72735-1|CAA51272.1| 533|Homo sapiens arylsulfatase protein. 55 5e-07
M32373-1|AAA51779.1| 533|Homo sapiens ARSB protein. 55 5e-07
J05225-1|AAA51784.1| 533|Homo sapiens ARSB protein. 55 5e-07
BC029051-1|AAH29051.1| 413|Homo sapiens arylsulfatase B protein. 55 5e-07
BC130438-1|AAI30439.1| 589|Homo sapiens arylsulfatase E (chondr... 54 1e-06
X83573-1|CAA58556.1| 589|Homo sapiens ARSE protein. 54 2e-06
AK223199-1|BAD96919.1| 589|Homo sapiens arylsulfatase E precurs... 54 2e-06
AK223183-1|BAD96903.1| 589|Homo sapiens arylsulfatase E precurs... 54 2e-06
BC068565-1|AAH68565.1| 644|Homo sapiens SULF1 protein protein. 53 3e-06
X52151-1|CAA36399.1| 507|Homo sapiens arylsulfatase A protein. 52 5e-06
X52150-1|CAA36398.1| 507|Homo sapiens arylsulphatase a protein. 52 5e-06
U62317-1|AAB03341.1| 509|Homo sapiens arylsulfatase A protein. 52 5e-06
CR456383-1|CAG30269.1| 509|Homo sapiens ARSA protein. 52 5e-06
BC014210-1|AAH14210.2| 507|Homo sapiens arylsulfatase A protein. 52 5e-06
AY875940-1|AAW66668.1| 562|Homo sapiens arylsulfatase H protein. 52 5e-06
AY271820-1|AAP03431.1| 507|Homo sapiens arylsulfatase A protein. 52 5e-06
X83572-1|CAA58555.1| 593|Homo sapiens ARSD protein. 48 8e-05
BC020229-1|AAH20229.1| 593|Homo sapiens ARSD protein protein. 48 8e-05
AF160499-1|AAF22253.1| 382|Homo sapiens arylsulfatase D beta pr... 48 8e-05
X97868-1|CAA66462.1| 591|Homo sapiens arylsulphatase protein. 48 1e-04
U60111-1|AAB17952.1| 502|Homo sapiens N-sulphoglucosamine sulph... 47 2e-04
U30894-1|AAA86530.1| 502|Homo sapiens N-sulphoglucosamine sulph... 47 2e-04
BC047318-1|AAH47318.1| 502|Homo sapiens N-sulfoglucosamine sulf... 47 2e-04
AK222890-1|BAD96610.1| 502|Homo sapiens N-sulfoglucosamine sulf... 47 2e-04
AB209900-1|BAD93137.1| 276|Homo sapiens N-sulfoglucosamine sulf... 47 2e-04
BC050392-1|AAH50392.1| 192|Homo sapiens ARSK protein protein. 46 3e-04
BC022389-1|AAH22389.1| 590|Homo sapiens ARSF protein protein. 46 3e-04
AL354813-1|CAI17942.1| 189|Homo sapiens RP5-1049G16.1 protein. 46 4e-04
BC129996-1|AAI29997.1| 569|Homo sapiens arylsulfatase family, m... 45 6e-04
BC129995-1|AAI29996.1| 569|Homo sapiens arylsulfatase family, m... 45 6e-04
AY875937-1|AAW66665.1| 569|Homo sapiens arylsulfatase I protein. 45 6e-04
M16505-1|AAA60596.1| 583|Homo sapiens STS protein. 44 0.001
J04964-1|AAA60597.1| 583|Homo sapiens STS protein. 44 0.001
BC075030-1|AAH75030.1| 583|Homo sapiens steroid sulfatase (micr... 44 0.001
BC132881-1|AAI32882.1| 599|Homo sapiens ARSJ protein protein. 42 0.007
BC132879-1|AAI32880.1| 599|Homo sapiens ARSJ protein protein. 42 0.007
BC089445-1|AAH89445.1| 578|Homo sapiens Unknown (protein for IM... 42 0.007
AY875938-1|AAW66666.1| 599|Homo sapiens arylsulfatase J protein. 42 0.007
AY358647-1|AAQ89010.1| 515|Homo sapiens APRG372 protein. 42 0.007
AM049401-1|CAJ18095.1| 596|Homo sapiens arylsulfatase J protein. 42 0.007
S57777-1|AAB19988.1| 104|Homo sapiens N-acetylgalactosamine-4- ... 39 0.048
BC012375-1|AAH12375.1| 525|Homo sapiens arylsulfatase G protein. 36 0.45
AY358380-1|AAQ88746.1| 525|Homo sapiens GWLF839 protein. 36 0.45
AB023218-1|BAA76845.2| 551|Homo sapiens KIAA1001 protein protein. 36 0.45
AF338230-1|AAK25791.1| 1278|Homo sapiens Niemann-Pick disease C1... 32 5.5
AF157379-1|AAD48006.1| 1278|Homo sapiens Niemann-Pick C1 protein... 32 5.5
AF002020-1|AAB63982.1| 1278|Homo sapiens Niemann-Pick C disease ... 32 5.5
>M58342-1|AAA63197.1| 550|Homo sapiens iduronate 2-sulfatase
protein.
Length = 550
Score = 436 bits (1074), Expect = e-122
Identities = 242/516 (46%), Positives = 312/516 (60%), Gaps = 49/516 (9%)
Query: 25 NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
N+L I++DDLR DK V PNI+ L F NAFAQQA+CAPSR S LTGRRP
Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97
Query: 81 DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
D+ RLYDF SYWR + GNF+TIPQ+FKE+GY T SVGKVFHPG SSN TDD PYSWS
Sbjct: 98 DTTRLYDFNSYWRVHA---GNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWS 154
Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK-R 199
PYHP +E Y++ K CR + L NL+CPV V P +LPD QS + AI L+K +
Sbjct: 155 FPPYHPSSEKYENTKTCRGPDGE-LHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMK 213
Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR 259
+ PFFLA+G+HKPHIP ++PKE+ K P+ + +P +P +P V+++PW D+R+R
Sbjct: 214 TSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQR 273
Query: 260 DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTS 315
+D++ LNI+ P+G +P + KIRQSY+A+ Y+D +G LLS +D TII TS
Sbjct: 274 EDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTS 333
Query: 316 DHGWSLGENGLWAKYSNFDYALKVPLIFKSP-----------KLIP--------TVVHEP 356
DHGW+LGE+G WAKYSNFD A VPLIF P KL P + + EP
Sbjct: 334 DHGWALGEHGEWAKYSNFDVATHVPLIFYVPGRTASLPEAGEKLFPYLDPFDSASQLMEP 393
Query: 357 -------VELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPF-----IENN-- 402
VEL+ +FPTL L L P+C +LC EGK+L+ +E +
Sbjct: 394 GRQSMDLVELVSLFPTLAGLAGLQVP-PRCPVPSFHVELCREGKNLLKHFRFRDLEEDPY 452
Query: 403 --SNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXX 460
N E A SQ PRPS PQ NSDKP LKDI IMGYSIRT YRYT W+
Sbjct: 453 LPGNPRELIAYSQYPRPSDIPQWNSDKPSLKDIKIMGYSIRTIDYRYTVWVGFNPDEFLA 512
Query: 461 XXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVL 496
+ ELY DP++ N++ S+ ++ ++L
Sbjct: 513 NFSDIHAGELYFVDSDPLQDHNMYNDSQGGDLFQLL 548
>L13329-1|AAA16877.1| 550|Homo sapiens iduronate-2-sulfatase
protein.
Length = 550
Score = 436 bits (1074), Expect = e-122
Identities = 242/516 (46%), Positives = 312/516 (60%), Gaps = 49/516 (9%)
Query: 25 NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
N+L I++DDLR DK V PNI+ L F NAFAQQA+CAPSR S LTGRRP
Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97
Query: 81 DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
D+ RLYDF SYWR + GNF+TIPQ+FKE+GY T SVGKVFHPG SSN TDD PYSWS
Sbjct: 98 DTTRLYDFNSYWRVHA---GNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWS 154
Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK-R 199
PYHP +E Y++ K CR + L NL+CPV V P +LPD QS + AI L+K +
Sbjct: 155 FPPYHPSSEKYENTKTCRGPDGE-LHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMK 213
Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR 259
+ PFFLA+G+HKPHIP ++PKE+ K P+ + +P +P +P V+++PW D+R+R
Sbjct: 214 TSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQR 273
Query: 260 DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTS 315
+D++ LNI+ P+G +P + KIRQSY+A+ Y+D +G LLS +D TII TS
Sbjct: 274 EDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTS 333
Query: 316 DHGWSLGENGLWAKYSNFDYALKVPLIFKSP-----------KLIP--------TVVHEP 356
DHGW+LGE+G WAKYSNFD A VPLIF P KL P + + EP
Sbjct: 334 DHGWALGEHGEWAKYSNFDVATHVPLIFYVPGRTASLPEAGEKLFPYLDPFDSASQLMEP 393
Query: 357 -------VELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPF-----IENN-- 402
VEL+ +FPTL L L P+C +LC EGK+L+ +E +
Sbjct: 394 GRQSMDLVELVSLFPTLAGLAGLQVP-PRCPVPSFHVELCREGKNLLKHFRFRDLEEDPY 452
Query: 403 --SNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXX 460
N E A SQ PRPS PQ NSDKP LKDI IMGYSIRT YRYT W+
Sbjct: 453 LPGNPRELIAYSQYPRPSDIPQWNSDKPSLKDIKIMGYSIRTIDYRYTVWVGFNPDEFLA 512
Query: 461 XXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVL 496
+ ELY DP++ N++ S+ ++ ++L
Sbjct: 513 NFSDIHAGELYFVDSDPLQDHNMYNDSQGGDLFQLL 548
>AF011889-1|AAC77828.1| 550|Homo sapiens iduronate 2-sulfatase
protein.
Length = 550
Score = 436 bits (1074), Expect = e-122
Identities = 242/516 (46%), Positives = 312/516 (60%), Gaps = 49/516 (9%)
Query: 25 NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
N+L I++DDLR DK V PNI+ L F NAFAQQA+CAPSR S LTGRRP
Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97
Query: 81 DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
D+ RLYDF SYWR + GNF+TIPQ+FKE+GY T SVGKVFHPG SSN TDD PYSWS
Sbjct: 98 DTTRLYDFNSYWRVHA---GNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWS 154
Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK-R 199
PYHP +E Y++ K CR + L NL+CPV V P +LPD QS + AI L+K +
Sbjct: 155 FPPYHPSSEKYENTKTCRGPDGE-LHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMK 213
Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR 259
+ PFFLA+G+HKPHIP ++PKE+ K P+ + +P +P +P V+++PW D+R+R
Sbjct: 214 TSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQR 273
Query: 260 DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTS 315
+D++ LNI+ P+G +P + KIRQSY+A+ Y+D +G LLS +D TII TS
Sbjct: 274 EDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTS 333
Query: 316 DHGWSLGENGLWAKYSNFDYALKVPLIFKSP-----------KLIP--------TVVHEP 356
DHGW+LGE+G WAKYSNFD A VPLIF P KL P + + EP
Sbjct: 334 DHGWALGEHGEWAKYSNFDVATHVPLIFYVPGRTASLPEAGEKLFPYLDPFDSASQLMEP 393
Query: 357 -------VELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPF-----IENN-- 402
VEL+ +FPTL L L P+C +LC EGK+L+ +E +
Sbjct: 394 GRQSMDLVELVSLFPTLAGLAGLQVP-PRCPVPSFHVELCREGKNLLKHFRFRDLEEDPY 452
Query: 403 --SNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXX 460
N E A SQ PRPS PQ NSDKP LKDI IMGYSIRT YRYT W+
Sbjct: 453 LPGNPRELIAYSQYPRPSDIPQWNSDKPSLKDIKIMGYSIRTIDYRYTVWVGFNPDEFLA 512
Query: 461 XXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVL 496
+ ELY DP++ N++ S+ ++ ++L
Sbjct: 513 NFSDIHAGELYFVDSDPLQDHNMYNDSQGGDLFQLL 548
>L04586-1|AAA59192.1| 398|Homo sapiens iduronate 2-sulfatase
protein.
Length = 398
Score = 370 bits (911), Expect = e-102
Identities = 178/331 (53%), Positives = 227/331 (68%), Gaps = 13/331 (3%)
Query: 25 NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
N+L I++DDLR DK V PNI+ L F NAFAQQA+CAPSR S LTGRRP
Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97
Query: 81 DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
D+ RLYDF SYWR + GNF+TIPQ+FKE+GY T SVGKVFHPG SSN TDD PYSWS
Sbjct: 98 DTTRLYDFNSYWRVHA---GNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWS 154
Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK-R 199
PYHP +E Y++ K CR + L NL+CPV V P +LPD QS + AI L+K +
Sbjct: 155 FPPYHPSSEKYENTKTCRGPDGE-LHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMK 213
Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR 259
+ PFFLA+G+HKPHIP ++PKE+ K P+ + +P +P +P V+++PW D+R+R
Sbjct: 214 TSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQR 273
Query: 260 DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTS 315
+D++ LNI+ P+G +P + KIRQSY+A+ Y+D +G LLS +D TII TS
Sbjct: 274 EDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTS 333
Query: 316 DHGWSLGENGLWAKYSNFDYALKVPLIFKSP 346
DHGW+LGE+G WAKYSNFD A VPLIF P
Sbjct: 334 DHGWALGEHGEWAKYSNFDVATHVPLIFYVP 364
>L40586-1|AAA92014.1| 343|Homo sapiens iduronate-2-sulphatase
protein.
Length = 343
Score = 328 bits (806), Expect = 3e-89
Identities = 159/309 (51%), Positives = 208/309 (67%), Gaps = 13/309 (4%)
Query: 25 NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
N+L I++DDLR DK V PNI+ L F NAFAQQA+CAPSR S LTGRRP
Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97
Query: 81 DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
D+ RLYDF SYWR + GNF+TIPQ+FKE+GY T SVGKVFHPG SSN TDD PYSWS
Sbjct: 98 DTTRLYDFNSYWRVHA---GNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWS 154
Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK-R 199
PYHP +E Y++ K CR + L NL+CPV V P +LPD QS + AI L+K +
Sbjct: 155 FPPYHPSSEKYENTKTCRGPDGE-LHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMK 213
Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR 259
+ PFFLA+G+HKPHIP ++PKE+ K P+ + +P +P +P V+++PW D+R+R
Sbjct: 214 TSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQR 273
Query: 260 DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTS 315
+D++ LNI+ P+G +P + KIRQSY+A+ Y+D +G LLS +D TII TS
Sbjct: 274 EDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTS 333
Query: 316 DHGWSLGEN 324
DHG+ + N
Sbjct: 334 DHGFLMRTN 342
>BC006170-1|AAH06170.1| 312|Homo sapiens IDS protein protein.
Length = 312
Score = 289 bits (710), Expect = 1e-77
Identities = 136/256 (53%), Positives = 177/256 (69%), Gaps = 9/256 (3%)
Query: 25 NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
N+L I++DDLR DK V PNI+ L F NAFAQQA+CAPSR S LTGRRP
Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97
Query: 81 DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
D+ RLYDF SYWR + GNF+TIPQ+FKE+GY T SVGKVFHPG SSN TDD PYSWS
Sbjct: 98 DTTRLYDFNSYWRVHA---GNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWS 154
Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK-R 199
PYHP +E Y++ K CR +L NL+CPV V P +LPD QS + AI L+K +
Sbjct: 155 FPPYHPSSEKYENTKTCRG-PDGELHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMK 213
Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR 259
+ PFFLA+G+HKPHIP ++PKE+ K P+ + +P +P +P V+++PW D+R+R
Sbjct: 214 TSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQR 273
Query: 260 DDIRRLNITFPFGVMP 275
+D++ LNI+ P+G +P
Sbjct: 274 EDVQALNISVPYGPIP 289
>AF050145-1|AAC05984.1| 179|Homo sapiens iduronate-2-sulfatase
protein.
Length = 179
Score = 131 bits (316), Expect = 6e-30
Identities = 66/106 (62%), Positives = 76/106 (71%), Gaps = 7/106 (6%)
Query: 25 NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
N+L I++DDLR DK V PNI+ L F NAFAQQA+CAPSR S LTGRRP
Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97
Query: 81 DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
D+ RLYDF SYWR + GNF+TIPQ+FKE+GY T SVGKVFHPG
Sbjct: 98 DTTRLYDFNSYWRVHA---GNFSTIPQYFKENGYVTMSVGKVFHPG 140
>L38660-1|AAB64180.1| 86|Homo sapiens iduronate-2-sulphatase
protein.
Length = 86
Score = 118 bits (284), Expect = 5e-26
Identities = 57/87 (65%), Positives = 65/87 (74%), Gaps = 3/87 (3%)
Query: 39 DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNG 98
D+ V PNI+ L F NAFAQQA+CAPSR S LTGRRPD+ RLYDF SYWR +
Sbjct: 3 DELVKAPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHA-- 60
Query: 99 QGNFTTIPQFFKEHGYDTYSVGKVFHP 125
GNF+TIPQ+FKE+GY T SVGKVFHP
Sbjct: 61 -GNFSTIPQYFKENGYVTMSVGKVFHP 86
>BC130329-1|AAI30330.1| 536|Homo sapiens arylsulfatase family,
member K protein.
Length = 536
Score = 85.8 bits (203), Expect = 3e-16
Identities = 86/345 (24%), Positives = 146/345 (42%), Gaps = 37/345 (10%)
Query: 36 HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDR 95
H + V LP INF+ G +F NA+ +C PSR ++ +G W +
Sbjct: 49 HPGSQVVKLPFINFMKTRGTSFLNAYTNSPICCPSRAAMWSGL------FTHLTESWNNF 102
Query: 96 SNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAK 155
N+TT + HGY T GK+ + + ++ + + E
Sbjct: 103 KGLDPNYTTWMDVMERHGYRTQKFGKLDYTSGHHSISNRVEAWTRDVAFLLRQEGRPMVN 162
Query: 156 VCRNK-KTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR--NGSKPFFLAIGFH 212
+ RN+ K + +ER D Q+ D A+++L+K N ++PF + +G +
Sbjct: 163 LIRNRTKVRVMER-----------------DWQNTDKAVNWLRKEAINYTEPFVIYLGLN 205
Query: 213 KPHIPLKFPKEYLKQMPISKVHRPKE--PNIPKD-MPLVSWHPWTDVRKRDDIRRLNITF 269
PH P P + S H + D + + W P +++ D
Sbjct: 206 LPH-PYPSPSSG-ENFGSSTFHTSLYWLEKVSHDAIKIPKWSPLSEMHPVDYYSSYTKNC 263
Query: 270 PFGVMPTKWTLKIRQSYYAAALYIDELIG---ILLSYVDM-QKTIIVLTSDHGWSLGENG 325
G K IR YYA D ++G + L +D+ QKTI++ +SDHG E+
Sbjct: 264 T-GRFTKKEIKNIRAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHGELAMEHR 322
Query: 326 LWAKYSNFDYALKVPLIFKSPKLIPTV-VHEPVELIDIFPTLVDL 369
+ K S ++ + VPL+ P + + V V L+DI+PT++D+
Sbjct: 323 QFYKMSMYEASAHVPLLMMGPGIKAGLQVSNVVSLVDIYPTMLDI 367
>BC036047-1|AAH36047.1| 542|Homo sapiens ARSK protein protein.
Length = 542
Score = 85.8 bits (203), Expect = 3e-16
Identities = 86/345 (24%), Positives = 146/345 (42%), Gaps = 37/345 (10%)
Query: 36 HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDR 95
H + V LP INF+ G +F NA+ +C PSR ++ +G W +
Sbjct: 55 HPGSQVVKLPFINFMKTRGTSFLNAYTNSPICCPSRAAMWSGL------FTHLTESWNNF 108
Query: 96 SNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAK 155
N+TT + HGY T GK+ + + ++ + + E
Sbjct: 109 KGLDPNYTTWMDVMERHGYRTQKFGKLDYTSGHHSISNRVEAWTRDVAFLLRQEGRPMVN 168
Query: 156 VCRNK-KTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR--NGSKPFFLAIGFH 212
+ RN+ K + +ER D Q+ D A+++L+K N ++PF + +G +
Sbjct: 169 LIRNRTKVRVMER-----------------DWQNTDKAVNWLRKEAINYTEPFVIYLGLN 211
Query: 213 KPHIPLKFPKEYLKQMPISKVHRPKE--PNIPKD-MPLVSWHPWTDVRKRDDIRRLNITF 269
PH P P + S H + D + + W P +++ D
Sbjct: 212 LPH-PYPSPSSG-ENFGSSTFHTSLYWLEKVSHDAIKIPKWSPLSEMHPVDYYSSYTKNC 269
Query: 270 PFGVMPTKWTLKIRQSYYAAALYIDELIG---ILLSYVDM-QKTIIVLTSDHGWSLGENG 325
G K IR YYA D ++G + L +D+ QKTI++ +SDHG E+
Sbjct: 270 T-GRFTKKEIKNIRAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHGELAMEHR 328
Query: 326 LWAKYSNFDYALKVPLIFKSPKLIPTV-VHEPVELIDIFPTLVDL 369
+ K S ++ + VPL+ P + + V V L+DI+PT++D+
Sbjct: 329 QFYKMSMYEASAHVPLLMMGPGIKAGLQVSNVVSLVDIYPTMLDI 373
>AY875939-1|AAW66667.1| 536|Homo sapiens arylsulfatase K protein.
Length = 536
Score = 85.8 bits (203), Expect = 3e-16
Identities = 86/345 (24%), Positives = 146/345 (42%), Gaps = 37/345 (10%)
Query: 36 HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDR 95
H + V LP INF+ G +F NA+ +C PSR ++ +G W +
Sbjct: 49 HPGSQVVKLPFINFMKTRGTSFLNAYTNSPICCPSRAAMWSGL------FTHLTESWNNF 102
Query: 96 SNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAK 155
N+TT + HGY T GK+ + + ++ + + E
Sbjct: 103 KGLDPNYTTWMDVMERHGYRTQKFGKLDYTSGHHSISNRVEAWTRDVAFLLRQEGRPMVN 162
Query: 156 VCRNK-KTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR--NGSKPFFLAIGFH 212
+ RN+ K + +ER D Q+ D A+++L+K N ++PF + +G +
Sbjct: 163 LIRNRTKVRVMER-----------------DWQNTDKAVNWLRKEAINYTEPFVIYLGLN 205
Query: 213 KPHIPLKFPKEYLKQMPISKVHRPKE--PNIPKD-MPLVSWHPWTDVRKRDDIRRLNITF 269
PH P P + S H + D + + W P +++ D
Sbjct: 206 LPH-PYPSPSSG-ENFGSSTFHTSLYWLEKVSHDAIKIPKWSPLSEMHPVDYYSSYTKNC 263
Query: 270 PFGVMPTKWTLKIRQSYYAAALYIDELIG---ILLSYVDM-QKTIIVLTSDHGWSLGENG 325
G K IR YYA D ++G + L +D+ QKTI++ +SDHG E+
Sbjct: 264 T-GRFTKKEIKNIRAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHGELAMEHR 322
Query: 326 LWAKYSNFDYALKVPLIFKSPKLIPTV-VHEPVELIDIFPTLVDL 369
+ K S ++ + VPL+ P + + V V L+DI+PT++D+
Sbjct: 323 QFYKMSMYEASAHVPLLMMGPGIKAGLQVSNVVSLVDIYPTMLDI 367
>AY358596-1|AAQ88959.1| 536|Homo sapiens Bone Rel Sulphatase
protein.
Length = 536
Score = 85.8 bits (203), Expect = 3e-16
Identities = 86/345 (24%), Positives = 146/345 (42%), Gaps = 37/345 (10%)
Query: 36 HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDR 95
H + V LP INF+ G +F NA+ +C PSR ++ +G W +
Sbjct: 49 HPGSQVVKLPFINFMKTRGTSFLNAYTNSPICCPSRAAMWSGL------FTHLTESWNNF 102
Query: 96 SNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAK 155
N+TT + HGY T GK+ + + ++ + + E
Sbjct: 103 KGLDPNYTTWMDVMERHGYRTQKFGKLDYTSGHHSISNRVEAWTRDVAFLLRQEGRPMVN 162
Query: 156 VCRNK-KTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR--NGSKPFFLAIGFH 212
+ RN+ K + +ER D Q+ D A+++L+K N ++PF + +G +
Sbjct: 163 LIRNRTKVRVMER-----------------DWQNTDKAVNWLRKEAINYTEPFVIYLGLN 205
Query: 213 KPHIPLKFPKEYLKQMPISKVHRPKE--PNIPKD-MPLVSWHPWTDVRKRDDIRRLNITF 269
PH P P + S H + D + + W P +++ D
Sbjct: 206 LPH-PYPSPSSG-ENFGSSTFHTSLYWLEKVSHDAIKIPKWSPLSEMHPVDYYSSYTKNC 263
Query: 270 PFGVMPTKWTLKIRQSYYAAALYIDELIG---ILLSYVDM-QKTIIVLTSDHGWSLGENG 325
G K IR YYA D ++G + L +D+ QKTI++ +SDHG E+
Sbjct: 264 T-GRFTKKEIKNIRAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHGELAMEHR 322
Query: 326 LWAKYSNFDYALKVPLIFKSPKLIPTV-VHEPVELIDIFPTLVDL 369
+ K S ++ + VPL+ P + + V V L+DI+PT++D+
Sbjct: 323 QFYKMSMYEASAHVPLLMMGPGIKAGLQVSNVVSLVDIYPTMLDI 367
>AL832711-1|CAD38634.1| 483|Homo sapiens hypothetical protein
protein.
Length = 483
Score = 84.2 bits (199), Expect = 1e-15
Identities = 85/339 (25%), Positives = 144/339 (42%), Gaps = 37/339 (10%)
Query: 42 VYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGN 101
V LP INF+ G +F NA+ +C PSR ++ +G W + N
Sbjct: 2 VKLPFINFMKTRGTSFLNAYTNSPICCPSRAAMWSGL------FTHLTESWNNFKGLDPN 55
Query: 102 FTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNK- 160
+TT + HGY T GK+ + + ++ + + E + RN+
Sbjct: 56 YTTWMDVMERHGYRTQKFGKLDYTSGHHSISNRVEAWTRDVAFLLRQEGRPMVNLIRNRT 115
Query: 161 KTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR--NGSKPFFLAIGFHKPHIPL 218
K + +ER D Q+ D A+++L+K N ++PF + +G + PH P
Sbjct: 116 KVRVMER-----------------DWQNTDKAVNWLRKEAINYTEPFVIYLGLNLPH-PY 157
Query: 219 KFPKEYLKQMPISKVHRPKE--PNIPKD-MPLVSWHPWTDVRKRDDIRRLNITFPFGVMP 275
P + S H + D + + W P +++ D G
Sbjct: 158 PSPSSG-ENFGSSTFHTSLYWLEKVSHDAIKIPKWSPLSEMHPVDYYSSYTKNCT-GRFT 215
Query: 276 TKWTLKIRQSYYAAALYIDELIG---ILLSYVDM-QKTIIVLTSDHGWSLGENGLWAKYS 331
K IR YYA D ++G + L +D+ QKTI++ +SDHG E+ + K S
Sbjct: 216 KKEIKNIRAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHGELAMEHRQFYKMS 275
Query: 332 NFDYALKVPLIFKSPKLIPTV-VHEPVELIDIFPTLVDL 369
++ + VPL+ P + + V V L+DI+PT++D+
Sbjct: 276 MYEASAHVPLLMMGPGIKAGLQVSNVVSLVDIYPTMLDI 314
>Z12173-1|CAA78164.1| 552|Homo sapiens
N-acetylglucosamine-6-sulphatase protein.
Length = 552
Score = 83.4 bits (197), Expect = 2e-15
Identities = 93/389 (23%), Positives = 162/389 (41%), Gaps = 40/389 (10%)
Query: 25 NILFILIDDLRHLSDKKVYLPNINFL-GKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
N++ +L DD + L L G+ G TF++A+ ALC PSR S+LTG+ P +
Sbjct: 48 NVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNH 107
Query: 84 RLYDFYSYWRDRSNGQGNF---TTIPQFFKEH-GYDTYSVGKVF--HPGKSSNFTDDYPY 137
+ + S T P + GY T+ GK + + + P
Sbjct: 108 HVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPL 167
Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
WS + Y + + N K +K N SV L D+ + + ++DFL
Sbjct: 168 GWSYWYALEKNSKYYNYTLSINGKARKHGEN----YSV-----DYLTDVLA-NVSLDFLD 217
Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVR 257
++ +PFF+ I PH P +Y Q V P+ N ++ + H W +
Sbjct: 218 YKSNFEPFFMMIATPAPHSPWTAAPQY--QKAFQNVFAPRNKNF--NIHGTNKH-WLIRQ 272
Query: 258 KRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDH 317
+ + +I F +W Q+ + +++L+ L ++ T I TSD+
Sbjct: 273 AKTPMTNSSIQFLDNAFRKRW-----QTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDN 327
Query: 318 GWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEP-VELIDIFPTLVDLTKLSDE 375
G+ G+ L K +++ +KVPL+ + P + P + V ID+ PT++D+
Sbjct: 328 GYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGY--- 384
Query: 376 IPKCLNHKDTSQLCFEGKSLVPFIENNSN 404
D ++ +G SL+P + SN
Sbjct: 385 --------DLNKTQMDGMSLLPILRGASN 405
>BC012482-1|AAH12482.1| 552|Homo sapiens glucosamine
(N-acetyl)-6-sulfatase (Sanfilippo disease IIID)
protein.
Length = 552
Score = 83.4 bits (197), Expect = 2e-15
Identities = 93/389 (23%), Positives = 162/389 (41%), Gaps = 40/389 (10%)
Query: 25 NILFILIDDLRHLSDKKVYLPNINFL-GKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
N++ +L DD + L L G+ G TF++A+ ALC PSR S+LTG+ P +
Sbjct: 48 NVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNH 107
Query: 84 RLYDFYSYWRDRSNGQGNF---TTIPQFFKEH-GYDTYSVGKVF--HPGKSSNFTDDYPY 137
+ + S T P + GY T+ GK + + + P
Sbjct: 108 HVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPL 167
Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
WS + Y + + N K +K N SV L D+ + + ++DFL
Sbjct: 168 GWSYWYALEKNSKYYNYTLSINGKARKHGEN----YSV-----DYLTDVLA-NVSLDFLD 217
Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVR 257
++ +PFF+ I PH P +Y Q V P+ N ++ + H W +
Sbjct: 218 YKSNFEPFFMMIATPAPHSPWTAAPQY--QKAFQNVFAPRNKNF--NIHGTNKH-WLIRQ 272
Query: 258 KRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDH 317
+ + +I F +W Q+ + +++L+ L ++ T I TSD+
Sbjct: 273 AKTPMTNSSIQFLDNAFRKRW-----QTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDN 327
Query: 318 GWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEP-VELIDIFPTLVDLTKLSDE 375
G+ G+ L K +++ +KVPL+ + P + P + V ID+ PT++D+
Sbjct: 328 GYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGY--- 384
Query: 376 IPKCLNHKDTSQLCFEGKSLVPFIENNSN 404
D ++ +G SL+P + SN
Sbjct: 385 --------DLNKTQMDGMSLLPILRGASN 405
>AK223484-1|BAD97204.1| 552|Homo sapiens glucosamine
(N-acetyl)-6-sulfatase precursor variant protein.
Length = 552
Score = 82.6 bits (195), Expect = 3e-15
Identities = 93/389 (23%), Positives = 162/389 (41%), Gaps = 40/389 (10%)
Query: 25 NILFILIDDLRHLSDKKVYLPNINFL-GKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
N++ +L DD + L L G+ G TF++A+ ALC PSR S+LTG+ P +
Sbjct: 48 NVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNH 107
Query: 84 RLYDFYSYWRDRSNGQGNF---TTIPQFFKEH-GYDTYSVGKVF--HPGKSSNFTDDYPY 137
+ + S T P + GY T+ GK + + + P
Sbjct: 108 HVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPL 167
Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
WS + Y + + N K +K N SV L D+ + + ++DFL
Sbjct: 168 GWSYWYALEKNSKYYNYTLSINGKARKHGEN----YSV-----DYLTDVLA-NVSLDFLD 217
Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVR 257
++ +PFF+ I PH P +Y Q V P+ N ++ + H W +
Sbjct: 218 YKSNFEPFFMMIATPAPHSPWTAAPQY--QKAFQNVCAPRNKNF--NIHGTNKH-WLIRQ 272
Query: 258 KRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDH 317
+ + +I F +W Q+ + +++L+ L ++ T I TSD+
Sbjct: 273 AKTPMTNSSIQFLDNAFRKRW-----QTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDN 327
Query: 318 GWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEP-VELIDIFPTLVDLTKLSDE 375
G+ G+ L K +++ +KVPL+ + P + P + V ID+ PT++D+
Sbjct: 328 GYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGY--- 384
Query: 376 IPKCLNHKDTSQLCFEGKSLVPFIENNSN 404
D ++ +G SL+P + SN
Sbjct: 385 --------DLNKTQMDGMSLLPILRGASN 405
>BX537363-1|CAD97608.1| 496|Homo sapiens hypothetical protein
protein.
Length = 496
Score = 81.0 bits (191), Expect = 9e-15
Identities = 87/363 (23%), Positives = 153/363 (42%), Gaps = 39/363 (10%)
Query: 50 LGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNF---TTIP 106
+G+ G TF++A+ ALC PSR S+LTG+ P + + + S T P
Sbjct: 18 IGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFP 77
Query: 107 QFFKEH-GYDTYSVGKVF--HPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTK 163
+ GY T+ GK + + + P WS + Y + + N K +
Sbjct: 78 AILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSKYYNYTLSINGKAR 137
Query: 164 KLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKE 223
K N SV L D+ + + ++DFL ++ +PFF+ I PH P +
Sbjct: 138 KHGEN----YSV-----DYLTDVLA-NVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQ 187
Query: 224 YLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIR 283
Y Q V P+ N ++ + H W + + + +I F +W
Sbjct: 188 Y--QKAFQNVFAPRNKNF--NIHGTNKH-WLIRQAKTPMTNSSIQFLDNAFRKRW----- 237
Query: 284 QSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWSLGENGL-WAKYSNFDYALKVPLI 342
Q+ + +++L+ L ++ T I TSD+G+ G+ L K +++ +KVPL+
Sbjct: 238 QTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLL 297
Query: 343 FKSPKLIPTVVHEP-VELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIEN 401
+ P + P + V ID+ PT++D+ D ++ +G SL+P +
Sbjct: 298 VRGPGIKPNQTSKMLVANIDLGPTILDIAGY-----------DLNKTQMDGMSLLPILRG 346
Query: 402 NSN 404
SN
Sbjct: 347 ASN 349
>AY101175-1|AAM76860.1| 871|Homo sapiens extracellular sulfatase
SULF-1 protein.
Length = 871
Score = 76.6 bits (180), Expect = 2e-13
Identities = 83/352 (23%), Positives = 145/352 (41%), Gaps = 25/352 (7%)
Query: 25 NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
NI+ +L DD L +V + GATF NAF +C PSR+S+LTG+ +
Sbjct: 44 NIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNH 103
Query: 84 RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
+Y S T + GY T GK + S P W E+
Sbjct: 104 NVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYI----PPGWREW 159
Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGS 202
+ + VCRN +K + L +S++Y K+
Sbjct: 160 LGLIKNSRFYNYTVCRNGIKEKHG------FDYAKDYFTDLITNESINY-FKMSKRMYPH 212
Query: 203 KPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDI 262
+P + I PH P ++ K P + H N +M H W ++ +
Sbjct: 213 RPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDK---H-WI-MQYTGPM 267
Query: 263 RRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWSLG 322
+++ F ++ K Q+ + ++ L +L+ +++ T I+ T+DHG+ +G
Sbjct: 268 LPIHMEFT-NILQRKRL----QTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIG 322
Query: 323 ENGL-WAKYSNFDYALKVPLIFKSPKLIP-TVVHEPVELIDIFPTLVDLTKL 372
+ GL K +D+ ++VP + P + P ++V + V ID+ PT++D+ L
Sbjct: 323 QFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNIDLAPTILDIAGL 374
>AF545571-1|AAO33315.1| 871|Homo sapiens sulfatase SULF1 precursor
protein.
Length = 871
Score = 73.7 bits (173), Expect = 1e-12
Identities = 82/352 (23%), Positives = 144/352 (40%), Gaps = 25/352 (7%)
Query: 25 NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
NI+ + DD L +V + GATF NAF +C PSR+S+LTG+ +
Sbjct: 44 NIILVPTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNH 103
Query: 84 RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
+Y S T + GY T GK + S P W E+
Sbjct: 104 NVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYI----PPGWREW 159
Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGS 202
+ + VCRN +K + L +S++Y K+
Sbjct: 160 LGLIKNSRFYNYTVCRNGIKEKHG------FDYAKDYFTDLITNESINY-FKMSKRMYPH 212
Query: 203 KPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDI 262
+P + I PH P ++ K P + H N +M H W ++ +
Sbjct: 213 RPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDK---H-WI-MQYTGPM 267
Query: 263 RRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWSLG 322
+++ F ++ K Q+ + ++ L +L+ +++ T I+ T+DHG+ +G
Sbjct: 268 LPIHMEFT-NILQRKRL----QTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIG 322
Query: 323 ENGL-WAKYSNFDYALKVPLIFKSPKLIP-TVVHEPVELIDIFPTLVDLTKL 372
+ GL K +D+ ++VP + P + P ++V + V ID+ PT++D+ L
Sbjct: 323 QFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNIDLAPTILDIAGL 374
>AB029000-1|BAA83029.1| 818|Homo sapiens KIAA1077 protein protein.
Length = 818
Score = 72.1 bits (169), Expect = 4e-12
Identities = 76/322 (23%), Positives = 134/322 (41%), Gaps = 24/322 (7%)
Query: 54 GATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRS-NGQGNFTTIPQFFKEH 112
GATF NAF +C PSR+S+LTG+ + +Y S T +
Sbjct: 21 GATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNT 80
Query: 113 GYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICP 172
GY T GK + S P W E+ + + VCRN +K
Sbjct: 81 GYRTAFFGKYLNEYNGSYI----PPGWREWLGLIKNSRFYNYTVCRNGIKEKHG------ 130
Query: 173 VSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISK 232
+ L +S++Y K+ +P + I PH P ++ K P +
Sbjct: 131 FDYAKDYFTDLITNESINY-FKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNAS 189
Query: 233 VHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALY 292
H N +M H W ++ + +++ F ++ K Q+ +
Sbjct: 190 QHITPSYNYAPNMDK---H-WI-MQYTGPMLPIHMEFT-NILQRKRL----QTLMSVDDS 239
Query: 293 IDELIGILLSYVDMQKTIIVLTSDHGWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIP- 350
++ L +L+ +++ T I+ T+DHG+ +G+ GL K +D+ ++VP + P + P
Sbjct: 240 VERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPG 299
Query: 351 TVVHEPVELIDIFPTLVDLTKL 372
++V + V ID+ PT++D+ L
Sbjct: 300 SIVPQIVLNIDLAPTILDIAGL 321
>BC110539-1|AAI10540.1| 870|Homo sapiens sulfatase 2 protein.
Length = 870
Score = 70.9 bits (166), Expect = 1e-11
Identities = 86/370 (23%), Positives = 148/370 (40%), Gaps = 31/370 (8%)
Query: 25 NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
NI+ +L DD L +V + + GA F NAF +C PSR+S+LTG+ +
Sbjct: 45 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNH 104
Query: 84 RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
Y S Q T + GY T GK + S P W E+
Sbjct: 105 NTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYV----PPGWKEW 160
Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL--KKRN 200
+ + +CRN +K + L DL + D F KK
Sbjct: 161 VGLLKNSRFYNYTLCRNGVKEKHGSDY---------SKDYLTDLITNDSVSFFRTSKKMY 211
Query: 201 GSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRD 260
+P + I PH P +Y + P + H N + P W +R
Sbjct: 212 PHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPN-PDKHWI----MRYTG 266
Query: 261 DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWS 320
++ +++ F K Q+ + ++ + +L+ ++ T IV T+DHG+
Sbjct: 267 PMKPIHMEFT-----NMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 321
Query: 321 LGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEPVEL-IDIFPTLVDLTKLSDEIPK 378
+G+ GL K +++ ++VP + P + ++ + L ID+ PT++D+ L +IP
Sbjct: 322 IGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGL--DIPA 379
Query: 379 CLNHKDTSQL 388
++ K +L
Sbjct: 380 DMDGKSILKL 389
>AY358461-1|AAQ88826.1| 867|Homo sapiens GPPS559 protein.
Length = 867
Score = 70.9 bits (166), Expect = 1e-11
Identities = 86/370 (23%), Positives = 148/370 (40%), Gaps = 31/370 (8%)
Query: 25 NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
NI+ +L DD L +V + + GA F NAF +C PSR+S+LTG+ +
Sbjct: 45 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNH 104
Query: 84 RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
Y S Q T + GY T GK + S P W E+
Sbjct: 105 NTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYV----PPGWKEW 160
Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL--KKRN 200
+ + +CRN +K + L DL + D F KK
Sbjct: 161 VGLLKNSRFYNYTLCRNGVKEKHGSDY---------SKDYLTDLITNDSVSFFRTSKKMY 211
Query: 201 GSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRD 260
+P + I PH P +Y + P + H N + P W +R
Sbjct: 212 PHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPN-PDKHWI----MRYTG 266
Query: 261 DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWS 320
++ +++ F K Q+ + ++ + +L+ ++ T IV T+DHG+
Sbjct: 267 PMKPIHMEFT-----NMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 321
Query: 321 LGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEPVEL-IDIFPTLVDLTKLSDEIPK 378
+G+ GL K +++ ++VP + P + ++ + L ID+ PT++D+ L +IP
Sbjct: 322 IGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGL--DIPA 379
Query: 379 CLNHKDTSQL 388
++ K +L
Sbjct: 380 DMDGKSILKL 389
>AY101176-1|AAM76861.1| 870|Homo sapiens extracellular sulfatase
SULF-2 protein.
Length = 870
Score = 70.9 bits (166), Expect = 1e-11
Identities = 86/370 (23%), Positives = 148/370 (40%), Gaps = 31/370 (8%)
Query: 25 NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
NI+ +L DD L +V + + GA F NAF +C PSR+S+LTG+ +
Sbjct: 45 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNH 104
Query: 84 RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
Y S Q T + GY T GK + S P W E+
Sbjct: 105 NTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYV----PPGWKEW 160
Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL--KKRN 200
+ + +CRN +K + L DL + D F KK
Sbjct: 161 VGLLKNSRFYNYTLCRNGVKEKHGSDY---------SKDYLTDLITNDSVSFFRTSKKMY 211
Query: 201 GSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRD 260
+P + I PH P +Y + P + H N + P W +R
Sbjct: 212 PHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPN-PDKHWI----MRYTG 266
Query: 261 DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWS 320
++ +++ F K Q+ + ++ + +L+ ++ T IV T+DHG+
Sbjct: 267 PMKPIHMEFT-----NMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 321
Query: 321 LGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEPVEL-IDIFPTLVDLTKLSDEIPK 378
+G+ GL K +++ ++VP + P + ++ + L ID+ PT++D+ L +IP
Sbjct: 322 IGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGL--DIPA 379
Query: 379 CLNHKDTSQL 388
++ K +L
Sbjct: 380 DMDGKSILKL 389
>AL354813-2|CAI17943.1| 870|Homo sapiens RP5-1049G16.1 protein.
Length = 870
Score = 70.9 bits (166), Expect = 1e-11
Identities = 86/370 (23%), Positives = 148/370 (40%), Gaps = 31/370 (8%)
Query: 25 NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
NI+ +L DD L +V + + GA F NAF +C PSR+S+LTG+ +
Sbjct: 45 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNH 104
Query: 84 RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
Y S Q T + GY T GK + S P W E+
Sbjct: 105 NTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYV----PPGWKEW 160
Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL--KKRN 200
+ + +CRN +K + L DL + D F KK
Sbjct: 161 VGLLKNSRFYNYTLCRNGVKEKHGSDY---------SKDYLTDLITNDSVSFFRTSKKMY 211
Query: 201 GSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRD 260
+P + I PH P +Y + P + H N + P W +R
Sbjct: 212 PHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPN-PDKHWI----MRYTG 266
Query: 261 DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWS 320
++ +++ F K Q+ + ++ + +L+ ++ T IV T+DHG+
Sbjct: 267 PMKPIHMEFT-----NMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 321
Query: 321 LGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEPVEL-IDIFPTLVDLTKLSDEIPK 378
+G+ GL K +++ ++VP + P + ++ + L ID+ PT++D+ L +IP
Sbjct: 322 IGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGL--DIPA 379
Query: 379 CLNHKDTSQL 388
++ K +L
Sbjct: 380 DMDGKSILKL 389
>AL034418-7|CAI42143.1| 870|Homo sapiens RP5-1049G16.1 protein.
Length = 870
Score = 70.9 bits (166), Expect = 1e-11
Identities = 86/370 (23%), Positives = 148/370 (40%), Gaps = 31/370 (8%)
Query: 25 NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
NI+ +L DD L +V + + GA F NAF +C PSR+S+LTG+ +
Sbjct: 45 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNH 104
Query: 84 RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
Y S Q T + GY T GK + S P W E+
Sbjct: 105 NTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYV----PPGWKEW 160
Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL--KKRN 200
+ + +CRN +K + L DL + D F KK
Sbjct: 161 VGLLKNSRFYNYTLCRNGVKEKHGSDY---------SKDYLTDLITNDSVSFFRTSKKMY 211
Query: 201 GSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRD 260
+P + I PH P +Y + P + H N + P W +R
Sbjct: 212 PHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPN-PDKHWI----MRYTG 266
Query: 261 DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWS 320
++ +++ F K Q+ + ++ + +L+ ++ T IV T+DHG+
Sbjct: 267 PMKPIHMEFT-----NMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 321
Query: 321 LGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEPVEL-IDIFPTLVDLTKLSDEIPK 378
+G+ GL K +++ ++VP + P + ++ + L ID+ PT++D+ L +IP
Sbjct: 322 IGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGL--DIPA 379
Query: 379 CLNHKDTSQL 388
++ K +L
Sbjct: 380 DMDGKSILKL 389
>AB033073-1|BAA86561.2| 885|Homo sapiens KIAA1247 protein protein.
Length = 885
Score = 69.3 bits (162), Expect = 3e-11
Identities = 85/370 (22%), Positives = 147/370 (39%), Gaps = 31/370 (8%)
Query: 25 NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
NI+ +L DD L +V + + G F NAF +C PSR+S+LTG+ +
Sbjct: 60 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNH 119
Query: 84 RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
Y S Q T + GY T GK + S P W E+
Sbjct: 120 NTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYV----PPGWKEW 175
Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL--KKRN 200
+ + +CRN +K + L DL + D F KK
Sbjct: 176 VGLLKNSRFYNYTLCRNGVKEKHGSDY---------SKDYLTDLITNDSVSFFRTSKKMY 226
Query: 201 GSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRD 260
+P + I PH P +Y + P + H N + P W +R
Sbjct: 227 PHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPN-PDKHWI----MRYTG 281
Query: 261 DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWS 320
++ +++ F K Q+ + ++ + +L+ ++ T IV T+DHG+
Sbjct: 282 PMKPIHMEFT-----NMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 336
Query: 321 LGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEPVEL-IDIFPTLVDLTKLSDEIPK 378
+G+ GL K +++ ++VP + P + ++ + L ID+ PT++D+ L +IP
Sbjct: 337 IGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGL--DIPA 394
Query: 379 CLNHKDTSQL 388
++ K +L
Sbjct: 395 DMDGKSILKL 404
>U06088-1|AAC51350.1| 522|Homo sapiens N-acetylgalactosamine
6-sulphatase protein.
Length = 522
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/236 (25%), Positives = 100/236 (42%), Gaps = 20/236 (8%)
Query: 7 IILLNGDRVLTSDVETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNA 60
+++L+ + S P NIL +L+DD+ D VY PN++ + G F N
Sbjct: 14 LLVLSAAGMGASGAPQPPNILLLLMDDMGW-GDLGVYGEPSRETPNLDRMAAEGLLFPNF 72
Query: 61 FAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQ-------GNFTTIPQFFKEHG 113
++ LC+PSR +LLTGR P Y ++ R+ Q + +P+ K+ G
Sbjct: 73 YSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAG 132
Query: 114 YDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYK-DAKVCRN---KKTKKLERNL 169
Y + VGK +H G F + + E+ P D K N + ++
Sbjct: 133 YVSKIVGK-WHLGHRPQF-HPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRY 190
Query: 170 ICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYL 225
+ + G++ L A+DF+K++ PFFL H P+ K +L
Sbjct: 191 YEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFL 246
>D17629-1|BAA04535.1| 522|Homo sapiens N-acetylgalactosamine
6-sulfate sulfatase protein.
Length = 522
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/236 (25%), Positives = 100/236 (42%), Gaps = 20/236 (8%)
Query: 7 IILLNGDRVLTSDVETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNA 60
+++L+ + S P NIL +L+DD+ D VY PN++ + G F N
Sbjct: 14 LLVLSAAGMGASGAPQPPNILLLLMDDMGW-GDLGVYGEPSRETPNLDRMAAEGLLFPNF 72
Query: 61 FAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQ-------GNFTTIPQFFKEHG 113
++ LC+PSR +LLTGR P Y ++ R+ Q + +P+ K+ G
Sbjct: 73 YSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAG 132
Query: 114 YDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYK-DAKVCRN---KKTKKLERNL 169
Y + VGK +H G F + + E+ P D K N + ++
Sbjct: 133 YVSKIVGK-WHLGHRPQF-HPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRY 190
Query: 170 ICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYL 225
+ + G++ L A+DF+K++ PFFL H P+ K +L
Sbjct: 191 YEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFL 246
>BC056151-1|AAH56151.1| 522|Homo sapiens galactosamine
(N-acetyl)-6-sulfate sulfatase (Morquio syndrome,
mucopolysacchar protein.
Length = 522
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/236 (25%), Positives = 100/236 (42%), Gaps = 20/236 (8%)
Query: 7 IILLNGDRVLTSDVETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNA 60
+++L+ + S P NIL +L+DD+ D VY PN++ + G F N
Sbjct: 14 LLVLSAAGMGASGAPQPPNILLLLMDDMGW-GDLGVYGEPSRETPNLDRMAAEGLLFPNF 72
Query: 61 FAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQ-------GNFTTIPQFFKEHG 113
++ LC+PSR +LLTGR P Y ++ R+ Q + +P+ K+ G
Sbjct: 73 YSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAG 132
Query: 114 YDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYK-DAKVCRN---KKTKKLERNL 169
Y + VGK +H G F + + E+ P D K N + ++
Sbjct: 133 YVSKIVGK-WHLGHRPQF-HPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRY 190
Query: 170 ICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYL 225
+ + G++ L A+DF+K++ PFFL H P+ K +L
Sbjct: 191 YEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFL 246
>BC050684-1|AAH50684.2| 522|Homo sapiens galactosamine
(N-acetyl)-6-sulfate sulfatase (Morquio syndrome,
mucopolysacchar protein.
Length = 522
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/236 (25%), Positives = 100/236 (42%), Gaps = 20/236 (8%)
Query: 7 IILLNGDRVLTSDVETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNA 60
+++L+ + S P NIL +L+DD+ D VY PN++ + G F N
Sbjct: 14 LLVLSAAGMGASGAPQPPNILLLLMDDMGW-GDLGVYGEPSRETPNLDRMAAEGLLFPNF 72
Query: 61 FAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQ-------GNFTTIPQFFKEHG 113
++ LC+PSR +LLTGR P Y ++ R+ Q + +P+ K+ G
Sbjct: 73 YSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAG 132
Query: 114 YDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYK-DAKVCRN---KKTKKLERNL 169
Y + VGK +H G F + + E+ P D K N + ++
Sbjct: 133 YVSKIVGK-WHLGHRPQF-HPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRY 190
Query: 170 ICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYL 225
+ + G++ L A+DF+K++ PFFL H P+ K +L
Sbjct: 191 YEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFL 246
>X72735-1|CAA51272.1| 533|Homo sapiens arylsulfatase protein.
Length = 533
Score = 55.2 bits (127), Expect = 5e-07
Identities = 57/215 (26%), Positives = 88/215 (40%), Gaps = 16/215 (7%)
Query: 23 PKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P +++F+L DDL ++ P+++ L G +N + Q LC PSR+ LLTGR
Sbjct: 44 PPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQP-LCTPSRSQLLTGR 102
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
L + S + +PQ KE GY T+ VGK +H G
Sbjct: 103 YQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGK-WHLGMYRKECLPTRRG 161
Query: 139 WSEY-PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVK--RQPGQSLPDLQSLDY---- 191
+ Y Y +E Y + C + R C + + + ++ S +
Sbjct: 162 FDTYFGYLLGSEDYYSHERCTLIDALNVTR---CALDFRDGEEVATGYKNMYSTNIFTKR 218
Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLK 226
AI + KP FL + H PL+ P+EYLK
Sbjct: 219 AIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLK 253
>M32373-1|AAA51779.1| 533|Homo sapiens ARSB protein.
Length = 533
Score = 55.2 bits (127), Expect = 5e-07
Identities = 57/215 (26%), Positives = 88/215 (40%), Gaps = 16/215 (7%)
Query: 23 PKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P +++F+L DDL ++ P+++ L G +N + Q LC PSR+ LLTGR
Sbjct: 44 PPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQP-LCTPSRSQLLTGR 102
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
L + S + +PQ KE GY T+ VGK +H G
Sbjct: 103 YQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGK-WHLGMYRKECLPTRRG 161
Query: 139 WSEY-PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVK--RQPGQSLPDLQSLDY---- 191
+ Y Y +E Y + C + R C + + + ++ S +
Sbjct: 162 FDTYFGYLLGSEDYYSHERCTLIDALNVTR---CALDFRDGEEVATGYKNMYSTNIFTKR 218
Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLK 226
AI + KP FL + H PL+ P+EYLK
Sbjct: 219 AIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLK 253
>J05225-1|AAA51784.1| 533|Homo sapiens ARSB protein.
Length = 533
Score = 55.2 bits (127), Expect = 5e-07
Identities = 57/215 (26%), Positives = 88/215 (40%), Gaps = 16/215 (7%)
Query: 23 PKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P +++F+L DDL ++ P+++ L G +N + Q LC PSR+ LLTGR
Sbjct: 44 PPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQP-LCTPSRSQLLTGR 102
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
L + S + +PQ KE GY T+ VGK +H G
Sbjct: 103 YQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGK-WHLGMYRKECLPTRRG 161
Query: 139 WSEY-PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVK--RQPGQSLPDLQSLDY---- 191
+ Y Y +E Y + C + R C + + + ++ S +
Sbjct: 162 FDTYFGYLLGSEDYYSHERCTLIDALNVTR---CALDFRDGEEVATGYKNMYSTNIFTKR 218
Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLK 226
AI + KP FL + H PL+ P+EYLK
Sbjct: 219 AIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLK 253
>BC029051-1|AAH29051.1| 413|Homo sapiens arylsulfatase B protein.
Length = 413
Score = 55.2 bits (127), Expect = 5e-07
Identities = 57/215 (26%), Positives = 88/215 (40%), Gaps = 16/215 (7%)
Query: 23 PKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P +++F+L DDL ++ P+++ L G +N + Q LC PSR+ LLTGR
Sbjct: 44 PPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQP-LCTPSRSQLLTGR 102
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
L + S + +PQ KE GY T+ VGK +H G
Sbjct: 103 YQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGK-WHLGMYRKECLPTRRG 161
Query: 139 WSEY-PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVK--RQPGQSLPDLQSLDY---- 191
+ Y Y +E Y + C + R C + + + ++ S +
Sbjct: 162 FDTYFGYLLGSEDYYSHERCTLIDALNVTR---CALDFRDGEEVATGYKNMYSTNIFTKR 218
Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLK 226
AI + KP FL + H PL+ P+EYLK
Sbjct: 219 AIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLK 253
>BC130438-1|AAI30439.1| 589|Homo sapiens arylsulfatase E
(chondrodysplasia punctata 1) protein.
Length = 589
Score = 54.0 bits (124), Expect = 1e-06
Identities = 44/140 (31%), Positives = 63/140 (45%), Gaps = 14/140 (10%)
Query: 8 ILLNGDRVLTSDVETPK-NILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNA 60
+LL+ +SD+ + NIL ++ DDL + D Y PNI+ L + G
Sbjct: 21 VLLSLAPSASSDISASRPNILLLMADDLG-IGDVGCYGNNTMRTPNIDRLAEDGVKLTQH 79
Query: 61 FAQQALCAPSRNSLLTGRRPDSLRLYDFYSY----WRDRSNG-QGNFTTIPQFFKEHGYD 115
+ +LC PSR + LTGR P + Y W S G N TT + KE GY
Sbjct: 80 ISAASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYA 139
Query: 116 TYSVGKVFHPGKSSNFTDDY 135
T +GK +H G + D+
Sbjct: 140 TGLIGK-WHLGLNCESASDH 158
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 21/105 (20%)
Query: 293 IDELIGILLSYVDMQ----KTIIVLTSDHGWSL----------GENGLWAK---YSNFDY 335
+D ++G +L +D++ T+I TSDHG SL G NG++ ++
Sbjct: 326 MDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEG 385
Query: 336 ALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIPK 378
++VP IF+ P ++P V+ EP L+D+FPT+V L E+P+
Sbjct: 386 GIRVPGIFRWPGVLPAGRVIGEPTSLMDVFPTVVRLA--GGEVPQ 428
>X83573-1|CAA58556.1| 589|Homo sapiens ARSE protein.
Length = 589
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/140 (31%), Positives = 63/140 (45%), Gaps = 14/140 (10%)
Query: 8 ILLNGDRVLTSDVETPK-NILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNA 60
+LL+ +SD+ + NIL ++ DDL + D Y PNI+ L + G
Sbjct: 21 VLLSLAPSASSDISASRPNILLLMADDLG-IGDIGCYGNNTMRTPNIDRLAEDGVKLTQH 79
Query: 61 FAQQALCAPSRNSLLTGRRPDSLRLYDFYSY----WRDRSNG-QGNFTTIPQFFKEHGYD 115
+ +LC PSR + LTGR P + Y W S G N TT + KE GY
Sbjct: 80 ISAASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYA 139
Query: 116 TYSVGKVFHPGKSSNFTDDY 135
T +GK +H G + D+
Sbjct: 140 TGLIGK-WHLGLNCESASDH 158
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 21/105 (20%)
Query: 293 IDELIGILLSYVDMQ----KTIIVLTSDHGWSL----------GENGLWAK---YSNFDY 335
+D ++G +L +D++ T+I TSDHG SL G NG++ ++
Sbjct: 326 MDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEG 385
Query: 336 ALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIPK 378
++VP IF+ P ++P V+ EP L+D+FPT+V L E+P+
Sbjct: 386 GIRVPGIFRWPGVLPAGRVIGEPTSLMDVFPTVVRLA--GGEVPQ 428
>AK223199-1|BAD96919.1| 589|Homo sapiens arylsulfatase E precursor
variant protein.
Length = 589
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/140 (31%), Positives = 63/140 (45%), Gaps = 14/140 (10%)
Query: 8 ILLNGDRVLTSDVETPK-NILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNA 60
+LL+ +SD+ + NIL ++ DDL + D Y PNI+ L + G
Sbjct: 21 VLLSLAPSASSDISASRPNILLLMADDLG-IGDIGCYGNNTMRTPNIDRLAEDGVKLTQH 79
Query: 61 FAQQALCAPSRNSLLTGRRPDSLRLYDFYSY----WRDRSNG-QGNFTTIPQFFKEHGYD 115
+ +LC PSR + LTGR P + Y W S G N TT + KE GY
Sbjct: 80 ISAASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYA 139
Query: 116 TYSVGKVFHPGKSSNFTDDY 135
T +GK +H G + D+
Sbjct: 140 TGLIGK-WHLGLNCESASDH 158
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 21/105 (20%)
Query: 293 IDELIGILLSYVDMQ----KTIIVLTSDHGWSL----------GENGLWAK---YSNFDY 335
+D ++G +L +D++ T+I TSDHG SL G NG++ ++
Sbjct: 326 MDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEG 385
Query: 336 ALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIPK 378
++VP IF+ P ++P V+ EP L+D+FPT+V L E+P+
Sbjct: 386 GIRVPGIFRWPGVLPAGRVIGEPTSLMDVFPTVVRLA--GGEVPQ 428
>AK223183-1|BAD96903.1| 589|Homo sapiens arylsulfatase E precursor
variant protein.
Length = 589
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/140 (31%), Positives = 63/140 (45%), Gaps = 14/140 (10%)
Query: 8 ILLNGDRVLTSDVETPK-NILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNA 60
+LL+ +SD+ + NIL ++ DDL + D Y PNI+ L + G
Sbjct: 21 VLLSLAPSASSDISASRPNILLLMADDLG-IGDIGCYGNNTMRTPNIDRLAEDGVKLTQH 79
Query: 61 FAQQALCAPSRNSLLTGRRPDSLRLYDFYSY----WRDRSNG-QGNFTTIPQFFKEHGYD 115
+ +LC PSR + LTGR P + Y W S G N TT + KE GY
Sbjct: 80 ISAASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYA 139
Query: 116 TYSVGKVFHPGKSSNFTDDY 135
T +GK +H G + D+
Sbjct: 140 TGLIGK-WHLGLNCESASDH 158
Score = 46.8 bits (106), Expect = 2e-04
Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 21/105 (20%)
Query: 293 IDELIGILLSYVDMQ----KTIIVLTSDHGWSL----------GENGLWAK---YSNFDY 335
+D ++G +L +D++ T+I TSDHG SL G NG++ ++
Sbjct: 326 MDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEG 385
Query: 336 ALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIPK 378
++VP IF+ P ++P V+ EP L+D+FPT+V L E+P+
Sbjct: 386 GIRVPGIFRWPGVLPAGRVIGEPTSLMDVFPTVVRLA--GSEVPQ 428
>BC068565-1|AAH68565.1| 644|Homo sapiens SULF1 protein protein.
Length = 644
Score = 52.8 bits (121), Expect = 3e-06
Identities = 25/82 (30%), Positives = 50/82 (60%), Gaps = 2/82 (2%)
Query: 293 IDELIGILLSYVDMQKTIIVLTSDHGWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIP- 350
++ L +L+ +++ T I+ T+DHG+ +G+ GL K +D+ ++VP + P + P
Sbjct: 52 VERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPG 111
Query: 351 TVVHEPVELIDIFPTLVDLTKL 372
++V + V ID+ PT++D+ L
Sbjct: 112 SIVPQIVLNIDLAPTILDIAGL 133
>X52151-1|CAA36399.1| 507|Homo sapiens arylsulfatase A protein.
Length = 507
Score = 52.0 bits (119), Expect = 5e-06
Identities = 62/219 (28%), Positives = 89/219 (40%), Gaps = 25/219 (11%)
Query: 20 VETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNS 73
V P NI+ I DDL + D Y PN++ L G F + + +LC PSR +
Sbjct: 17 VARPPNIVLIFADDLGY-GDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAA 75
Query: 74 LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNF 131
LLTGR P + +Y R T+ + GY T GK +H G F
Sbjct: 76 LLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGK-WHLGVGPEGAF 134
Query: 132 TDDY---------PYSWSEYPYHPPTEMYKDAKVCRNKKTKKL-ERNLICPVSVKRQPGQ 181
+ PYS + P T + A C + L L+ +SV+ QP
Sbjct: 135 LPPHQGFHRFLGIPYSHDQGPCQNLT-CFPPATPCDGGCDQGLVPIPLLANLSVEAQP-P 192
Query: 182 SLPDLQS--LDYAIDFL-KKRNGSKPFFLAIGFHKPHIP 217
LP L++ + +A D + + +PFFL H H P
Sbjct: 193 WLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYP 231
>X52150-1|CAA36398.1| 507|Homo sapiens arylsulphatase a protein.
Length = 507
Score = 52.0 bits (119), Expect = 5e-06
Identities = 62/219 (28%), Positives = 89/219 (40%), Gaps = 25/219 (11%)
Query: 20 VETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNS 73
V P NI+ I DDL + D Y PN++ L G F + + +LC PSR +
Sbjct: 17 VARPPNIVLIFADDLGY-GDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAA 75
Query: 74 LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNF 131
LLTGR P + +Y R T+ + GY T GK +H G F
Sbjct: 76 LLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGK-WHLGVGPEGAF 134
Query: 132 TDDY---------PYSWSEYPYHPPTEMYKDAKVCRNKKTKKL-ERNLICPVSVKRQPGQ 181
+ PYS + P T + A C + L L+ +SV+ QP
Sbjct: 135 LPPHQGFHRFLGIPYSHDQGPCQNLT-CFPPATPCDGGCDQGLVPIPLLANLSVEAQP-P 192
Query: 182 SLPDLQS--LDYAIDFL-KKRNGSKPFFLAIGFHKPHIP 217
LP L++ + +A D + + +PFFL H H P
Sbjct: 193 WLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYP 231
>U62317-1|AAB03341.1| 509|Homo sapiens arylsulfatase A protein.
Length = 509
Score = 52.0 bits (119), Expect = 5e-06
Identities = 62/219 (28%), Positives = 89/219 (40%), Gaps = 25/219 (11%)
Query: 20 VETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNS 73
V P NI+ I DDL + D Y PN++ L G F + + +LC PSR +
Sbjct: 19 VARPPNIVLIFADDLGY-GDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAA 77
Query: 74 LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNF 131
LLTGR P + +Y R T+ + GY T GK +H G F
Sbjct: 78 LLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGK-WHLGVGPEGAF 136
Query: 132 TDDY---------PYSWSEYPYHPPTEMYKDAKVCRNKKTKKL-ERNLICPVSVKRQPGQ 181
+ PYS + P T + A C + L L+ +SV+ QP
Sbjct: 137 LPPHQGFHRFLGIPYSHDQGPCQNLT-CFPPATPCDGGCDQGLVPIPLLANLSVEAQP-P 194
Query: 182 SLPDLQS--LDYAIDFL-KKRNGSKPFFLAIGFHKPHIP 217
LP L++ + +A D + + +PFFL H H P
Sbjct: 195 WLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYP 233
>CR456383-1|CAG30269.1| 509|Homo sapiens ARSA protein.
Length = 509
Score = 52.0 bits (119), Expect = 5e-06
Identities = 62/219 (28%), Positives = 89/219 (40%), Gaps = 25/219 (11%)
Query: 20 VETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNS 73
V P NI+ I DDL + D Y PN++ L G F + + +LC PSR +
Sbjct: 19 VARPPNIVLIFADDLGY-GDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAA 77
Query: 74 LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNF 131
LLTGR P + +Y R T+ + GY T GK +H G F
Sbjct: 78 LLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGK-WHLGVGPEGAF 136
Query: 132 TDDY---------PYSWSEYPYHPPTEMYKDAKVCRNKKTKKL-ERNLICPVSVKRQPGQ 181
+ PYS + P T + A C + L L+ +SV+ QP
Sbjct: 137 LPPHQGFHRFLGIPYSHDQGPCQNLT-CFPPATPCDGGCDQGLVPIPLLANLSVEAQP-P 194
Query: 182 SLPDLQS--LDYAIDFL-KKRNGSKPFFLAIGFHKPHIP 217
LP L++ + +A D + + +PFFL H H P
Sbjct: 195 WLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYP 233
>BC014210-1|AAH14210.2| 507|Homo sapiens arylsulfatase A protein.
Length = 507
Score = 52.0 bits (119), Expect = 5e-06
Identities = 62/219 (28%), Positives = 89/219 (40%), Gaps = 25/219 (11%)
Query: 20 VETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNS 73
V P NI+ I DDL + D Y PN++ L G F + + +LC PSR +
Sbjct: 17 VARPPNIVLIFADDLGY-GDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAA 75
Query: 74 LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNF 131
LLTGR P + +Y R T+ + GY T GK +H G F
Sbjct: 76 LLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGK-WHLGVGPEGAF 134
Query: 132 TDDY---------PYSWSEYPYHPPTEMYKDAKVCRNKKTKKL-ERNLICPVSVKRQPGQ 181
+ PYS + P T + A C + L L+ +SV+ QP
Sbjct: 135 LPPHQGFHRFLGIPYSHDQGPCQNLT-CFPPATPCDGGCDQGLVPIPLLANLSVEAQP-P 192
Query: 182 SLPDLQS--LDYAIDFL-KKRNGSKPFFLAIGFHKPHIP 217
LP L++ + +A D + + +PFFL H H P
Sbjct: 193 WLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYP 231
>AY875940-1|AAW66668.1| 562|Homo sapiens arylsulfatase H protein.
Length = 562
Score = 52.0 bits (119), Expect = 5e-06
Identities = 43/147 (29%), Positives = 62/147 (42%), Gaps = 14/147 (9%)
Query: 31 IDDLRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYS 90
+ DL + V PNI+ L G A ++C PSR + LTGR P + Y+
Sbjct: 19 VGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGRYPIRSGMVSAYN 78
Query: 91 Y-----WRDRSNG-QGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPY 144
W S G N TT + + GY T +GK +H G S +D+ Y + +
Sbjct: 79 LNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGK-WHLGLSCASRNDHCYHPLNHGF 137
Query: 145 H----PPTEMYKDAKVCRNKKTKKLER 167
H P + D C+ KT +L R
Sbjct: 138 HYFYGVPFGLLSD---CQASKTPELHR 161
Score = 37.5 bits (83), Expect = 0.11
Identities = 27/93 (29%), Positives = 50/93 (53%), Gaps = 19/93 (20%)
Query: 293 IDELIGILLSYVDMQK----TIIVLTSDHGWSL----------GENGLWAK---YSNFDY 335
+D ++G +L +D ++ T++ TSD+G L G NG++ ++
Sbjct: 296 MDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEG 355
Query: 336 ALKVPLIFKSPKLIPT--VVHEPVELIDIFPTL 366
++VP IF+ P ++ V++EP L+DI+PTL
Sbjct: 356 GIRVPGIFRWPSVLEAGRVINEPTSLMDIYPTL 388
>AY271820-1|AAP03431.1| 507|Homo sapiens arylsulfatase A protein.
Length = 507
Score = 52.0 bits (119), Expect = 5e-06
Identities = 62/219 (28%), Positives = 89/219 (40%), Gaps = 25/219 (11%)
Query: 20 VETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNS 73
V P NI+ I DDL + D Y PN++ L G F + + +LC PSR +
Sbjct: 17 VARPPNIVLIFADDLGY-GDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAA 75
Query: 74 LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNF 131
LLTGR P + +Y R T+ + GY T GK +H G F
Sbjct: 76 LLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGK-WHLGVGPEGAF 134
Query: 132 TDDY---------PYSWSEYPYHPPTEMYKDAKVCRNKKTKKL-ERNLICPVSVKRQPGQ 181
+ PYS + P T + A C + L L+ +SV+ QP
Sbjct: 135 LPPHQGFHRFLGIPYSHDQGPCQNLT-CFPPATPCDGGCDQGLVPIPLLANLSVEAQP-P 192
Query: 182 SLPDLQS--LDYAIDFL-KKRNGSKPFFLAIGFHKPHIP 217
LP L++ + +A D + + +PFFL H H P
Sbjct: 193 WLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYP 231
>X83572-1|CAA58555.1| 593|Homo sapiens ARSD protein.
Length = 593
Score = 48.0 bits (109), Expect = 8e-05
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 11/112 (9%)
Query: 25 NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
NIL I+ DDL + + PNI+ L + G A LC PSR + LTGR
Sbjct: 42 NILLIMADDLGTGDLGCYGNNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRAAFLTGRH 101
Query: 80 PDSLRLYDFYSY----WRDRSNG-QGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
+ Y W S G N TT + ++HGY T +GK +H G
Sbjct: 102 SFRSGMDASNGYRALQWNAGSGGLPENETTFARILQQHGYATGLIGK-WHQG 152
Score = 41.1 bits (92), Expect = 0.009
Identities = 38/127 (29%), Positives = 61/127 (48%), Gaps = 29/127 (22%)
Query: 293 IDELIGILLSYVD----MQKTIIVLTSDHGWSL----------GENGLWAK---YSNFDY 335
+D LIG +L+ ++ T TSDHG L G NG++ ++
Sbjct: 329 MDWLIGKVLNAIEDNGLKNSTFTYFTSDHGGHLEARDGHSQLGGWNGIYKGGKGMGGWEG 388
Query: 336 ALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGK 393
++VP IF P ++P V+ EP L+D+FPT+V L + E+P+ +G
Sbjct: 389 GIRVPGIFHWPGVLPAGRVIGEPTSLMDVFPTVVQL--VGGEVPQ--------DRVIDGH 438
Query: 394 SLVPFIE 400
SLVP ++
Sbjct: 439 SLVPLLQ 445
>BC020229-1|AAH20229.1| 593|Homo sapiens ARSD protein protein.
Length = 593
Score = 48.0 bits (109), Expect = 8e-05
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 11/112 (9%)
Query: 25 NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
NIL I+ DDL + + PNI+ L + G A LC PSR + LTGR
Sbjct: 42 NILLIMADDLGTGDLGCYGNNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRAAFLTGRH 101
Query: 80 PDSLRLYDFYSY----WRDRSNG-QGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
+ Y W S G N TT + ++HGY T +GK +H G
Sbjct: 102 SFRSGMDASNGYRALQWNAGSGGLPENETTFARILQQHGYATGLIGK-WHQG 152
Score = 41.1 bits (92), Expect = 0.009
Identities = 38/127 (29%), Positives = 61/127 (48%), Gaps = 29/127 (22%)
Query: 293 IDELIGILLSYVD----MQKTIIVLTSDHGWSL----------GENGLWAK---YSNFDY 335
+D LIG +L+ ++ T TSDHG L G NG++ ++
Sbjct: 329 MDWLIGKVLNAIEDNGLKNSTFTYFTSDHGGHLEARDGHSQLGGWNGIYKGGKGMGGWEG 388
Query: 336 ALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGK 393
++VP IF P ++P V+ EP L+D+FPT+V L + E+P+ +G
Sbjct: 389 GIRVPGIFHWPGVLPAGRVIGEPTSLMDVFPTVVQL--VGGEVPQ--------DRVIDGH 438
Query: 394 SLVPFIE 400
SLVP ++
Sbjct: 439 SLVPLLQ 445
>AF160499-1|AAF22253.1| 382|Homo sapiens arylsulfatase D beta
protein.
Length = 382
Score = 48.0 bits (109), Expect = 8e-05
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 11/112 (9%)
Query: 25 NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
NIL I+ DDL + + PNI+ L + G A LC PSR + LTGR
Sbjct: 42 NILLIMADDLGTGDLGCYGNNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRAAFLTGRH 101
Query: 80 PDSLRLYDFYSY----WRDRSNG-QGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
+ Y W S G N TT + ++HGY T +GK +H G
Sbjct: 102 SFRSGMDASNGYRALQWNAGSGGLPENETTFARILQQHGYATGLIGK-WHQG 152
>X97868-1|CAA66462.1| 591|Homo sapiens arylsulphatase protein.
Length = 591
Score = 47.6 bits (108), Expect = 1e-04
Identities = 42/146 (28%), Positives = 70/146 (47%), Gaps = 17/146 (11%)
Query: 17 TSDVETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPS 70
T + T NI+ I++DDL + D Y P+I+ L + G + +LC+PS
Sbjct: 24 TGCMTTRPNIVLIMVDDLG-IGDLGCYGNDTMRTPHIDRLAREGVRLTQHISAASLCSPS 82
Query: 71 RNSLLTGRRPDSLRLYDFYS--YWRDRSNGQG---NFTTIPQFFKEHGYDTYSVGKVFHP 125
R++ LTGR P + + ++ + G N TT+ K+ GY T +GK +H
Sbjct: 83 RSAFLTGRYPIRSGMVSSGNRRVIQNLAVPAGLPLNETTLAALLKKQGYSTGLIGK-WHQ 141
Query: 126 GKSSNFTDD---YPYSWS-EYPYHPP 147
G + + D +PY++ +Y Y P
Sbjct: 142 GLNCDSRSDQCHHPYNYGFDYYYGMP 167
Score = 35.5 bits (78), Expect = 0.45
Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 19/97 (19%)
Query: 293 IDELIGILLSYVD----MQKTIIVLTSDHGWSL----------GENGLWAK---YSNFDY 335
+D ++G +L +D T++ TSDHG L G NG++ ++
Sbjct: 319 MDSMVGKILDAIDDFGLRNNTLVYFTSDHGGHLEARRGHAQLGGWNGIYKGGKGMGGWEG 378
Query: 336 ALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLT 370
++VP I + P +P ++ EP L+DI PT+ ++
Sbjct: 379 GIRVPGIVRWPGKVPAGRLIKEPTSLMDILPTVASVS 415
>U60111-1|AAB17952.1| 502|Homo sapiens N-sulphoglucosamine
sulphohydrolase protein.
Length = 502
Score = 46.8 bits (106), Expect = 2e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 6/120 (5%)
Query: 23 PKNILFILIDDLRHLS----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P+N L +L DD S + + P+++ L + F NAF + C+PSR SLLTG
Sbjct: 22 PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGL 81
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
+Y + N ++P + G T +GK H G + + D+ Y+
Sbjct: 82 PQHQNGMYGLHQDVH-HFNSFDKVRSLPLLLSQAGVRTGIIGKK-HVGPETVYPFDFAYT 139
>U30894-1|AAA86530.1| 502|Homo sapiens N-sulphoglucosamine
sulphohydrolase protein.
Length = 502
Score = 46.8 bits (106), Expect = 2e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 6/120 (5%)
Query: 23 PKNILFILIDDLRHLS----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P+N L +L DD S + + P+++ L + F NAF + C+PSR SLLTG
Sbjct: 22 PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGL 81
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
+Y + N ++P + G T +GK H G + + D+ Y+
Sbjct: 82 PQHQNGMYGLHQDVH-HFNSFDKVRSLPLLLSQAGVRTGIIGKK-HVGPETVYPFDFAYT 139
>BC047318-1|AAH47318.1| 502|Homo sapiens N-sulfoglucosamine
sulfohydrolase (sulfamidase) protein.
Length = 502
Score = 46.8 bits (106), Expect = 2e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 6/120 (5%)
Query: 23 PKNILFILIDDLRHLS----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P+N L +L DD S + + P+++ L + F NAF + C+PSR SLLTG
Sbjct: 22 PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGL 81
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
+Y + N ++P + G T +GK H G + + D+ Y+
Sbjct: 82 PQHQNGMYGLHQDVH-HFNSFDKVRSLPLLLSQAGVRTGIIGKK-HVGPETVYPFDFAYT 139
>AK222890-1|BAD96610.1| 502|Homo sapiens N-sulfoglucosamine
sulfohydrolase (sulfamidase) variant protein.
Length = 502
Score = 46.8 bits (106), Expect = 2e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 6/120 (5%)
Query: 23 PKNILFILIDDLRHLS----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P+N L +L DD S + + P+++ L + F NAF + C+PSR SLLTG
Sbjct: 22 PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGL 81
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
+Y + N ++P + G T +GK H G + + D+ Y+
Sbjct: 82 PQHQNGMYGLHQDVH-HFNSFDKVRSLPLLLSQAGVRTGIIGKK-HVGPETVYPFDFAYT 139
>AB209900-1|BAD93137.1| 276|Homo sapiens N-sulfoglucosamine
sulfohydrolase (sulfamidase) variant protein.
Length = 276
Score = 46.8 bits (106), Expect = 2e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 6/120 (5%)
Query: 23 PKNILFILIDDLRHLS----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P+N L +L DD S + + P+++ L + F NAF + C+PSR SLLTG
Sbjct: 25 PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGL 84
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
+Y + N ++P + G T +GK H G + + D+ Y+
Sbjct: 85 PQHQNGMYGLHQDVH-HFNSFDKVRSLPLLLSQAGVRTGIIGKK-HVGPETVYPFDFAYT 142
>BC050392-1|AAH50392.1| 192|Homo sapiens ARSK protein protein.
Length = 192
Score = 46.0 bits (104), Expect = 3e-04
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 6/87 (6%)
Query: 36 HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDR 95
H + V LP INF+ G +F NA+ +C PSR ++ +G W +
Sbjct: 88 HPGSQVVKLPFINFMKTRGTSFLNAYTNSPICCPSRAAMWSG------LFTHLTESWNNF 141
Query: 96 SNGQGNFTTIPQFFKEHGYDTYSVGKV 122
N+TT + HGY T GK+
Sbjct: 142 KGLDPNYTTWMDVMERHGYRTQKFGKL 168
>BC022389-1|AAH22389.1| 590|Homo sapiens ARSF protein protein.
Length = 590
Score = 46.0 bits (104), Expect = 3e-04
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 17/138 (12%)
Query: 25 NILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
NI+ I++DDL + D Y P+I+ L + G + +LC+PSR++ LTGR
Sbjct: 31 NIVLIMVDDLG-IGDLGCYGNDTMRTPHIDRLAREGVRLTQHISAASLCSPSRSAFLTGR 89
Query: 79 RPDSLRLYDFYS--YWRDRSNGQG---NFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTD 133
P + + ++ + G N TT+ K+ GY T +GK +H G + +
Sbjct: 90 YPIRSGMVSSGNRRVIQNLAVPAGLPLNETTLAALLKKQGYSTGLIGK-WHQGLNCDSRS 148
Query: 134 D---YPYSWS-EYPYHPP 147
D +PY++ +Y Y P
Sbjct: 149 DQCHHPYNYGFDYYYGMP 166
Score = 35.5 bits (78), Expect = 0.45
Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 19/97 (19%)
Query: 293 IDELIGILLSYVD----MQKTIIVLTSDHGWSL----------GENGLWAK---YSNFDY 335
+D ++G +L +D T++ TSDHG L G NG++ ++
Sbjct: 318 MDSMVGKILDAIDDFGLRNNTLVYFTSDHGGHLEARRGHAQLGGWNGIYKGGKGMGGWEG 377
Query: 336 ALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLT 370
++VP I + P +P ++ EP L+DI PT+ ++
Sbjct: 378 GIRVPGIVRWPGKVPAGRLIKEPTSLMDILPTVASVS 414
>AL354813-1|CAI17942.1| 189|Homo sapiens RP5-1049G16.1 protein.
Length = 189
Score = 45.6 bits (103), Expect = 4e-04
Identities = 38/142 (26%), Positives = 55/142 (38%), Gaps = 6/142 (4%)
Query: 25 NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
NI+ +L DD L +V + + GA F NAF +C PSR+S+LTG+ +
Sbjct: 45 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNH 104
Query: 84 RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
Y S Q T + GY T GK + S P W E+
Sbjct: 105 NTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSY----VPPGWKEW 160
Query: 143 PYHPPTEMYKDAKVCRNKKTKK 164
+ + +CRN +K
Sbjct: 161 VGLLKNSRFYNYTLCRNGVKEK 182
>BC129996-1|AAI29997.1| 569|Homo sapiens arylsulfatase family,
member I protein.
Length = 569
Score = 45.2 bits (102), Expect = 6e-04
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 6/108 (5%)
Query: 23 PKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P +I+FIL DD + + P ++ L G N + Q +C PSR+ LLTGR
Sbjct: 46 PPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQP-ICTPSRSQLLTGR 104
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
L + + + T+PQ +E GY T+ VGK +H G
Sbjct: 105 YQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGK-WHLG 151
Score = 31.5 bits (68), Expect = 7.3
Identities = 13/34 (38%), Positives = 18/34 (52%)
Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYL 225
A L + +P FL + F H PL+ P+EYL
Sbjct: 216 ASHILASHSPQRPLFLYVAFQAVHTPLQSPREYL 249
>BC129995-1|AAI29996.1| 569|Homo sapiens arylsulfatase family,
member I protein.
Length = 569
Score = 45.2 bits (102), Expect = 6e-04
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 6/108 (5%)
Query: 23 PKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P +I+FIL DD + + P ++ L G N + Q +C PSR+ LLTGR
Sbjct: 46 PPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQP-ICTPSRSQLLTGR 104
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
L + + + T+PQ +E GY T+ VGK +H G
Sbjct: 105 YQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGK-WHLG 151
Score = 31.5 bits (68), Expect = 7.3
Identities = 13/34 (38%), Positives = 18/34 (52%)
Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYL 225
A L + +P FL + F H PL+ P+EYL
Sbjct: 216 ASHILASHSPQRPLFLYVAFQAVHTPLQSPREYL 249
>AY875937-1|AAW66665.1| 569|Homo sapiens arylsulfatase I protein.
Length = 569
Score = 45.2 bits (102), Expect = 6e-04
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 6/108 (5%)
Query: 23 PKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P +I+FIL DD + + P ++ L G N + Q +C PSR+ LLTGR
Sbjct: 46 PPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQP-ICTPSRSQLLTGR 104
Query: 79 RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
L + + + T+PQ +E GY T+ VGK +H G
Sbjct: 105 YQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGK-WHLG 151
Score = 31.5 bits (68), Expect = 7.3
Identities = 13/34 (38%), Positives = 18/34 (52%)
Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYL 225
A L + +P FL + F H PL+ P+EYL
Sbjct: 216 ASHILASHSPQRPLFLYVAFQAVHTPLQSPREYL 249
>M16505-1|AAA60596.1| 583|Homo sapiens STS protein.
Length = 583
Score = 44.4 bits (100), Expect = 0.001
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 11/121 (9%)
Query: 25 NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
NI+ ++ DDL +K + PNI+ L G A LC PSR + +TGR
Sbjct: 28 NIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTGRY 87
Query: 80 P--DSLRLYDFYSYWRDRSNGQGNFT---TIPQFFKEHGYDTYSVGKVFHPGKSSNFTDD 134
P + + + ++ G T T + K+ GY T +GK +H G S + D
Sbjct: 88 PVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGK-WHLGMSCHSKTD 146
Query: 135 Y 135
+
Sbjct: 147 F 147
Score = 37.1 bits (82), Expect = 0.15
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 5/77 (6%)
Query: 322 GENGLW--AKYSNFDYALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIP 377
G NG++ K +N++ ++VP I + P++I + EP +DIFPT+ L
Sbjct: 359 GSNGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPED 418
Query: 378 KCLNHKDTSQLCFEGKS 394
+ ++ +D L EGKS
Sbjct: 419 RIIDGRDLMPL-LEGKS 434
>J04964-1|AAA60597.1| 583|Homo sapiens STS protein.
Length = 583
Score = 44.4 bits (100), Expect = 0.001
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 11/121 (9%)
Query: 25 NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
NI+ ++ DDL +K + PNI+ L G A LC PSR + +TGR
Sbjct: 28 NIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTGRY 87
Query: 80 P--DSLRLYDFYSYWRDRSNGQGNFT---TIPQFFKEHGYDTYSVGKVFHPGKSSNFTDD 134
P + + + ++ G T T + K+ GY T +GK +H G S + D
Sbjct: 88 PVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGK-WHLGMSCHSKTD 146
Query: 135 Y 135
+
Sbjct: 147 F 147
Score = 37.1 bits (82), Expect = 0.15
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 5/77 (6%)
Query: 322 GENGLW--AKYSNFDYALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIP 377
G NG++ K +N++ ++VP I + P++I + EP +DIFPT+ L
Sbjct: 359 GSNGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPED 418
Query: 378 KCLNHKDTSQLCFEGKS 394
+ ++ +D L EGKS
Sbjct: 419 RIIDGRDLMPL-LEGKS 434
>BC075030-1|AAH75030.1| 583|Homo sapiens steroid sulfatase
(microsomal), arylsulfatase C, isozyme S protein.
Length = 583
Score = 44.4 bits (100), Expect = 0.001
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 11/121 (9%)
Query: 25 NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
NI+ ++ DDL +K + PNI+ L G A LC PSR + +TGR
Sbjct: 28 NIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTGRY 87
Query: 80 P--DSLRLYDFYSYWRDRSNGQGNFT---TIPQFFKEHGYDTYSVGKVFHPGKSSNFTDD 134
P + + + ++ G T T + K+ GY T +GK +H G S + D
Sbjct: 88 PVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGK-WHLGMSCHSKTD 146
Query: 135 Y 135
+
Sbjct: 147 F 147
Score = 37.1 bits (82), Expect = 0.15
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 5/77 (6%)
Query: 322 GENGLW--AKYSNFDYALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIP 377
G NG++ K +N++ ++VP I + P++I + EP +DIFPT+ L
Sbjct: 359 GSNGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPED 418
Query: 378 KCLNHKDTSQLCFEGKS 394
+ ++ +D L EGKS
Sbjct: 419 RIIDGRDLMPL-LEGKS 434
>BC132881-1|AAI32882.1| 599|Homo sapiens ARSJ protein protein.
Length = 599
Score = 41.5 bits (93), Expect = 0.007
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 12 GDRVLTSDVETPK-NILFILIDD--LRHLS--DKKVYLPNINFLGKTGATFNNAFAQQAL 66
G+++ S T + +++FIL DD R + ++ P ++ L G N + Q +
Sbjct: 63 GEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQP-I 121
Query: 67 CAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
C PSR+ +TG+ L + + T+PQ KE GY T+ VGK +H G
Sbjct: 122 CTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGK-WHLG 180
>BC132879-1|AAI32880.1| 599|Homo sapiens ARSJ protein protein.
Length = 599
Score = 41.5 bits (93), Expect = 0.007
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 12 GDRVLTSDVETPK-NILFILIDD--LRHLS--DKKVYLPNINFLGKTGATFNNAFAQQAL 66
G+++ S T + +++FIL DD R + ++ P ++ L G N + Q +
Sbjct: 63 GEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQP-I 121
Query: 67 CAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
C PSR+ +TG+ L + + T+PQ KE GY T+ VGK +H G
Sbjct: 122 CTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGK-WHLG 180
>BC089445-1|AAH89445.1| 578|Homo sapiens Unknown (protein for
IMAGE:30706925) protein.
Length = 578
Score = 41.5 bits (93), Expect = 0.007
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 12 GDRVLTSDVETPK-NILFILIDD--LRHLS--DKKVYLPNINFLGKTGATFNNAFAQQAL 66
G+++ S T + +++FIL DD R + ++ P ++ L G N + Q +
Sbjct: 63 GEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQP-I 121
Query: 67 CAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
C PSR+ +TG+ L + + T+PQ KE GY T+ VGK +H G
Sbjct: 122 CTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGK-WHLG 180
>AY875938-1|AAW66666.1| 599|Homo sapiens arylsulfatase J protein.
Length = 599
Score = 41.5 bits (93), Expect = 0.007
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 12 GDRVLTSDVETPK-NILFILIDD--LRHLS--DKKVYLPNINFLGKTGATFNNAFAQQAL 66
G+++ S T + +++FIL DD R + ++ P ++ L G N + Q +
Sbjct: 63 GEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQP-I 121
Query: 67 CAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
C PSR+ +TG+ L + + T+PQ KE GY T+ VGK +H G
Sbjct: 122 CTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGK-WHLG 180
>AY358647-1|AAQ89010.1| 515|Homo sapiens APRG372 protein.
Length = 515
Score = 41.5 bits (93), Expect = 0.007
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 12 GDRVLTSDVETPK-NILFILIDD--LRHLS--DKKVYLPNINFLGKTGATFNNAFAQQAL 66
G+++ S T + +++FIL DD R + ++ P ++ L G N + Q +
Sbjct: 63 GEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQP-I 121
Query: 67 CAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
C PSR+ +TG+ L + + T+PQ KE GY T+ VGK +H G
Sbjct: 122 CTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGK-WHLG 180
>AM049401-1|CAJ18095.1| 596|Homo sapiens arylsulfatase J protein.
Length = 596
Score = 41.5 bits (93), Expect = 0.007
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 12 GDRVLTSDVETPK-NILFILIDD--LRHLS--DKKVYLPNINFLGKTGATFNNAFAQQAL 66
G+++ S T + +++FIL DD R + ++ P ++ L G N + Q +
Sbjct: 63 GEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQP-I 121
Query: 67 CAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
C PSR+ +TG+ L + + T+PQ KE GY T+ VGK +H G
Sbjct: 122 CTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGK-WHLG 180
>S57777-1|AAB19988.1| 104|Homo sapiens N-acetylgalactosamine-4-
sulphatase protein.
Length = 104
Score = 38.7 bits (86), Expect = 0.048
Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 23 PKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
P +++F+L DDL ++ P+++ L G +N + Q LC PSR+ LLTGR
Sbjct: 44 PPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQP-LCTPSRSQLLTGR 102
>BC012375-1|AAH12375.1| 525|Homo sapiens arylsulfatase G protein.
Length = 525
Score = 35.5 bits (78), Expect = 0.45
Identities = 47/194 (24%), Positives = 83/194 (42%), Gaps = 23/194 (11%)
Query: 46 NINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQG-NFTT 104
N++ + G F + A + C+PSR SLLTGR LR ++ G N TT
Sbjct: 63 NLDKMASEGMRFVDFHAAASTCSPSRASLLTGRL--GLRNGVTRNFAVTSVGGLPLNETT 120
Query: 105 IPQFFKEHGYDTYSVGK-------VFHPG-KSSNFTDDYPYSWSEYPYHPPTEMYKDAKV 156
+ + ++ GY T +GK +HP + ++ PYS P +
Sbjct: 121 LAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPA 180
Query: 157 C--RNKKTKKLERNLICPVSVKRQPGQSLPD----LQSL-----DYAIDFLKKRNGS-KP 204
C + ++ L+R+ V++ ++ + L SL + A F+++ + S +P
Sbjct: 181 CPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRP 240
Query: 205 FFLAIGFHKPHIPL 218
F L + H+PL
Sbjct: 241 FLLYVALAHMHVPL 254
Score = 31.9 bits (69), Expect = 5.5
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 319 WSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEP--VELIDIFPTLVDLTKLSDEI 376
W + G AK + ++ +VP + P +P V + ++DIFPT+V L + S
Sbjct: 323 WQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQ 382
Query: 377 PKCLNHKDTSQLCFEGKS 394
+ + D S++ F G+S
Sbjct: 383 GRRFDGVDVSEVLF-GRS 399
>AY358380-1|AAQ88746.1| 525|Homo sapiens GWLF839 protein.
Length = 525
Score = 35.5 bits (78), Expect = 0.45
Identities = 47/194 (24%), Positives = 83/194 (42%), Gaps = 23/194 (11%)
Query: 46 NINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQG-NFTT 104
N++ + G F + A + C+PSR SLLTGR LR ++ G N TT
Sbjct: 63 NLDKMASEGMRFVDFHAAASTCSPSRASLLTGRL--GLRNGVTRNFAVTSVGGLPLNETT 120
Query: 105 IPQFFKEHGYDTYSVGK-------VFHPG-KSSNFTDDYPYSWSEYPYHPPTEMYKDAKV 156
+ + ++ GY T +GK +HP + ++ PYS P +
Sbjct: 121 LAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPA 180
Query: 157 C--RNKKTKKLERNLICPVSVKRQPGQSLPD----LQSL-----DYAIDFLKKRNGS-KP 204
C + ++ L+R+ V++ ++ + L SL + A F+++ + S +P
Sbjct: 181 CPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRP 240
Query: 205 FFLAIGFHKPHIPL 218
F L + H+PL
Sbjct: 241 FLLYVALAHMHVPL 254
Score = 31.9 bits (69), Expect = 5.5
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 319 WSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEP--VELIDIFPTLVDLTKLSDEI 376
W + G AK + ++ +VP + P +P V + ++DIFPT+V L + S
Sbjct: 323 WQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQ 382
Query: 377 PKCLNHKDTSQLCFEGKS 394
+ + D S++ F G+S
Sbjct: 383 GRRFDGVDVSEVLF-GRS 399
>AB023218-1|BAA76845.2| 551|Homo sapiens KIAA1001 protein protein.
Length = 551
Score = 35.5 bits (78), Expect = 0.45
Identities = 47/194 (24%), Positives = 83/194 (42%), Gaps = 23/194 (11%)
Query: 46 NINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQG-NFTT 104
N++ + G F + A + C+PSR SLLTGR LR ++ G N TT
Sbjct: 89 NLDKMASEGMRFVDFHAAASTCSPSRASLLTGRL--GLRNGVTRNFAVTSVGGLPLNETT 146
Query: 105 IPQFFKEHGYDTYSVGK-------VFHPG-KSSNFTDDYPYSWSEYPYHPPTEMYKDAKV 156
+ + ++ GY T +GK +HP + ++ PYS P +
Sbjct: 147 LAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPA 206
Query: 157 C--RNKKTKKLERNLICPVSVKRQPGQSLPD----LQSL-----DYAIDFLKKRNGS-KP 204
C + ++ L+R+ V++ ++ + L SL + A F+++ + S +P
Sbjct: 207 CPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRP 266
Query: 205 FFLAIGFHKPHIPL 218
F L + H+PL
Sbjct: 267 FLLYVALAHMHVPL 280
Score = 31.9 bits (69), Expect = 5.5
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 319 WSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEP--VELIDIFPTLVDLTKLSDEI 376
W + G AK + ++ +VP + P +P V + ++DIFPT+V L + S
Sbjct: 349 WQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQ 408
Query: 377 PKCLNHKDTSQLCFEGKS 394
+ + D S++ F G+S
Sbjct: 409 GRRFDGVDVSEVLF-GRS 425
>AF338230-1|AAK25791.1| 1278|Homo sapiens Niemann-Pick disease C1
protein protein.
Length = 1278
Score = 31.9 bits (69), Expect = 5.5
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 8/70 (11%)
Query: 54 GATFNNAF--AQQALCAPSRNS----LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQ 107
G +F NA A + + APS N LL G+ D+ ++ Y ++ NGQ FT P
Sbjct: 149 GQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPV 208
Query: 108 F--FKEHGYD 115
F F HG +
Sbjct: 209 FSDFPVHGME 218
>AF157379-1|AAD48006.1| 1278|Homo sapiens Niemann-Pick C1 protein
protein.
Length = 1278
Score = 31.9 bits (69), Expect = 5.5
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 8/70 (11%)
Query: 54 GATFNNAF--AQQALCAPSRNS----LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQ 107
G +F NA A + + APS N LL G+ D+ ++ Y ++ NGQ FT P
Sbjct: 149 GQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPV 208
Query: 108 F--FKEHGYD 115
F F HG +
Sbjct: 209 FSDFPVHGME 218
>AF002020-1|AAB63982.1| 1278|Homo sapiens Niemann-Pick C disease
protein protein.
Length = 1278
Score = 31.9 bits (69), Expect = 5.5
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 8/70 (11%)
Query: 54 GATFNNAF--AQQALCAPSRNS----LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQ 107
G +F NA A + + APS N LL G+ D+ ++ Y ++ NGQ FT P
Sbjct: 149 GQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPV 208
Query: 108 F--FKEHGYD 115
F F HG +
Sbjct: 209 FSDFPVHGME 218
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.139 0.430
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 79,567,712
Number of Sequences: 224733
Number of extensions: 3568622
Number of successful extensions: 9243
Number of sequences better than 10.0: 77
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 9029
Number of HSP's gapped (non-prelim): 150
length of query: 508
length of database: 73,234,838
effective HSP length: 93
effective length of query: 415
effective length of database: 52,334,669
effective search space: 21718887635
effective search space used: 21718887635
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
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