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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001291-TA|BGIBMGA001291-PA|IPR000917|Sulfatase
         (508 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q4V5Y6 Cluster: IP11830p; n=10; Endopterygota|Rep: IP11...   459   e-128
UniRef50_UPI00015B5B4A Cluster: PREDICTED: similar to iduronate ...   452   e-126
UniRef50_UPI0000ECC490 Cluster: Iduronate 2-sulfatase precursor ...   437   e-121
UniRef50_P22304 Cluster: Iduronate 2-sulfatase precursor (EC 3.1...   436   e-121
UniRef50_Q08890 Cluster: Iduronate 2-sulfatase precursor; n=22; ...   431   e-119
UniRef50_UPI0000DB7794 Cluster: PREDICTED: similar to CG12014-PA...   425   e-117
UniRef50_A7SLQ8 Cluster: Predicted protein; n=1; Nematostella ve...   423   e-117
UniRef50_UPI0000E489EA Cluster: PREDICTED: similar to Iduronate ...   346   1e-93
UniRef50_A6CFT9 Cluster: Iduronate-2-sulfatase; n=1; Planctomyce...   231   2e-59
UniRef50_A3ZYV7 Cluster: Iduronate-2-sulfatase; n=1; Blastopirel...   219   1e-55
UniRef50_A7AE03 Cluster: Putative uncharacterized protein; n=1; ...   213   7e-54
UniRef50_Q482E2 Cluster: Sulfatase family protein; n=1; Colwelli...   204   4e-51
UniRef50_A4A047 Cluster: Iduronate-2-sulfatase; n=1; Blastopirel...   204   4e-51
UniRef50_A6DJJ1 Cluster: Sulfatase family protein; n=1; Lentisph...   200   7e-50
UniRef50_Q7UVD4 Cluster: Iduronate-2-sulfatase; n=1; Pirellula s...   195   3e-48
UniRef50_A6DPD0 Cluster: Sulfatase family protein; n=1; Lentisph...   190   6e-47
UniRef50_A6DFZ4 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaer...   190   6e-47
UniRef50_Q7UZ92 Cluster: Iduronate-2-sulfatase; n=1; Pirellula s...   190   7e-47
UniRef50_Q7UJ67 Cluster: Iduronate-2-sulfatase; n=1; Pirellula s...   190   7e-47
UniRef50_A6DME6 Cluster: Sulfatase family protein; n=1; Lentisph...   188   2e-46
UniRef50_A6DGT7 Cluster: Sulfatase family protein; n=1; Lentisph...   186   2e-45
UniRef50_Q482B9 Cluster: Sulfatase family protein; n=1; Colwelli...   185   2e-45
UniRef50_Q482C5 Cluster: Sulfatase family protein; n=1; Colwelli...   182   2e-44
UniRef50_A6DPE5 Cluster: Iduronate-2-sulfatase; n=2; Lentisphaer...   175   2e-42
UniRef50_Q7UWE8 Cluster: Iduronate-2-sulfatase; n=1; Pirellula s...   173   9e-42
UniRef50_A6CG48 Cluster: Sulfatase family protein; n=1; Planctom...   169   1e-40
UniRef50_Q7UW58 Cluster: Iduronate-2-sulfatase; n=1; Pirellula s...   166   1e-39
UniRef50_UPI0000E0F7B6 Cluster: iduronate 2-sulfatase precursor;...   165   3e-39
UniRef50_Q7URV9 Cluster: Iduronate-2-sulfatase; n=2; Bacteria|Re...   164   4e-39
UniRef50_A6C9F6 Cluster: Iduronate-2-sulfatase; n=1; Planctomyce...   162   2e-38
UniRef50_A4AWR8 Cluster: Iduronate-2-sulfatase; n=5; Bacteria|Re...   161   3e-38
UniRef50_A6DJM0 Cluster: Sulfatase family protein; n=1; Lentisph...   161   4e-38
UniRef50_UPI0000E11054 Cluster: iduronate-2-sulfatase; n=1; alph...   156   1e-36
UniRef50_A4APQ8 Cluster: Iduronate-2-sulfatase; n=3; Bacteroidet...   155   3e-36
UniRef50_A6DSH1 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaer...   155   3e-36
UniRef50_Q7UJQ7 Cluster: Iduronate-2-sulfatase; n=2; Planctomyce...   154   5e-36
UniRef50_A3HTC6 Cluster: Choline sulfatase; n=1; Algoriphagus sp...   153   8e-36
UniRef50_Q1YTH2 Cluster: Sulfatase family protein; n=1; gamma pr...   151   4e-35
UniRef50_A3ZMC3 Cluster: Iduronate sulfatase; n=2; Planctomyceta...   149   2e-34
UniRef50_UPI0000E11068 Cluster: iduronate-sulfatase (partial) an...   145   2e-33
UniRef50_A6L183 Cluster: Iduronate 2-sulfatase; n=2; Bacteroides...   144   4e-33
UniRef50_A6DNH1 Cluster: Choline sulfatase; n=2; Lentisphaera ar...   144   4e-33
UniRef50_Q8A3P0 Cluster: Iduronate 2-sulfatase; n=2; Bacteroides...   144   5e-33
UniRef50_A6DG72 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaer...   144   5e-33
UniRef50_Q7UER3 Cluster: Iduronate-2-sulfatase; n=1; Pirellula s...   142   1e-32
UniRef50_A6C6J6 Cluster: Iduronate-2-sulfatase; n=2; Bacteria|Re...   142   1e-32
UniRef50_A7ADK4 Cluster: Putative uncharacterized protein; n=1; ...   141   5e-32
UniRef50_A6DKB6 Cluster: Iduronate sulfatase; n=1; Lentisphaera ...   140   6e-32
UniRef50_A6DJ24 Cluster: Iduronate-2-sulfatase; n=3; Lentisphaer...   138   3e-31
UniRef50_A6DGD4 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaer...   133   1e-29
UniRef50_Q7UYA8 Cluster: Iduronate-2-sulfatase; n=1; Pirellula s...   132   3e-29
UniRef50_A4A280 Cluster: Iduronate-2-sulfatase; n=1; Blastopirel...   131   4e-29
UniRef50_A6DJE6 Cluster: Iduronate sulfatase; n=1; Lentisphaera ...   130   6e-29
UniRef50_A7LXD1 Cluster: Putative uncharacterized protein; n=1; ...   130   1e-28
UniRef50_A6DSH0 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaer...   128   5e-28
UniRef50_A0LK86 Cluster: Sulfatase precursor; n=1; Syntrophobact...   128   5e-28
UniRef50_Q7UXP2 Cluster: Iduronate sulfatase; n=1; Pirellula sp....   125   2e-27
UniRef50_A6DIH4 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaer...   125   3e-27
UniRef50_A6DGD8 Cluster: Iduronate-sulfatase and sulfatase 1; n=...   125   3e-27
UniRef50_Q7UQN9 Cluster: Choline sulfatase; n=3; Planctomycetace...   123   1e-26
UniRef50_A6DSG8 Cluster: Iduronate sulfatase; n=1; Lentisphaera ...   123   1e-26
UniRef50_Q7ULE7 Cluster: Iduronate-sulfatase and sulfatase 1; n=...   123   1e-26
UniRef50_UPI0000D9F62E Cluster: PREDICTED: similar to Iduronate ...   122   2e-26
UniRef50_A5AB40 Cluster: Catalytic activity: choline sulfate + H...   119   2e-25
UniRef50_A3ZT15 Cluster: Iduronate-2-sulfatase; n=1; Blastopirel...   116   1e-24
UniRef50_A4GIA7 Cluster: Iduronate sulfatase; n=1; uncultured ma...   113   1e-23
UniRef50_Q7WC54 Cluster: Putative sulfatase; n=3; Proteobacteria...   113   1e-23
UniRef50_UPI000051016C Cluster: COG3119: Arylsulfatase A and rel...   112   2e-23
UniRef50_Q4WLI2 Cluster: Choline sulfatase, putative; n=7; Eurot...   111   6e-23
UniRef50_A6RD60 Cluster: Putative uncharacterized protein; n=1; ...   111   6e-23
UniRef50_A4U8Q3 Cluster: Sulfatase; n=2; Bacteria|Rep: Sulfatase...   109   2e-22
UniRef50_A6DFB2 Cluster: Iduronate-sulfatase and sulfatase 1; n=...   108   3e-22
UniRef50_A6C1R0 Cluster: Choline sulfatase; n=1; Planctomyces ma...   105   2e-21
UniRef50_A6DNH0 Cluster: Choline sulfatase; n=1; Lentisphaera ar...   104   6e-21
UniRef50_Q15XH4 Cluster: Sulfatase precursor; n=1; Pseudoalterom...   101   6e-20
UniRef50_A0GDT1 Cluster: Sulfatase; n=1; Burkholderia phytofirma...   101   6e-20
UniRef50_Q46P27 Cluster: Sulfatase; n=2; Bacteria|Rep: Sulfatase...    98   4e-19
UniRef50_Q17CP8 Cluster: Sulfatase; n=2; Culicidae|Rep: Sulfatas...    97   7e-19
UniRef50_A6C9S7 Cluster: Choline sulfatase; n=1; Planctomyces ma...    97   1e-18
UniRef50_A6DGE4 Cluster: Iduronate-sulfatase and sulfatase 1; n=...    96   2e-18
UniRef50_A4AMS2 Cluster: Choline sulfatase; n=1; Flavobacteriale...    96   2e-18
UniRef50_O69787 Cluster: Choline-sulfatase; n=28; Alphaproteobac...    96   2e-18
UniRef50_Q62DH2 Cluster: Choline sulfatase; n=37; cellular organ...    96   2e-18
UniRef50_A3SJ21 Cluster: Sulfatase; n=1; Roseovarius nubinhibens...    96   2e-18
UniRef50_Q8XNV1 Cluster: Sulfatase; n=2; Clostridium perfringens...    96   2e-18
UniRef50_A6DKC4 Cluster: Iduronate-sulfatase and sulfatase 1; n=...    95   3e-18
UniRef50_A4ASX5 Cluster: Mucin-desulfating sulfatase; n=1; Flavo...    95   5e-18
UniRef50_A7A9X1 Cluster: Putative uncharacterized protein; n=1; ...    94   7e-18
UniRef50_A6DJ72 Cluster: Mucin-desulfating sulfatase; n=1; Lenti...    93   1e-17
UniRef50_A6DQC0 Cluster: Mucin-desulfating sulfatase; n=1; Lenti...    93   2e-17
UniRef50_Q7UMT6 Cluster: Mucin-desulfating sulfatase; n=2; Bacte...    92   3e-17
UniRef50_A6DMR1 Cluster: Iduronate sulfatase; n=2; Lentisphaera ...    92   3e-17
UniRef50_A6DJ01 Cluster: Putative N-acetylglucosamine-6-sulfatas...    92   4e-17
UniRef50_A6C2T4 Cluster: Sulfatase; n=1; Planctomyces maris DSM ...    92   4e-17
UniRef50_Q650K5 Cluster: Choline-sulfatase; n=7; Bacteroidales|R...    91   5e-17
UniRef50_A6DG34 Cluster: Choline sulfatase; n=1; Lentisphaera ar...    91   5e-17
UniRef50_Q4V902 Cluster: Zgc:114066; n=17; Eumetazoa|Rep: Zgc:11...    91   6e-17
UniRef50_Q7UPQ8 Cluster: Choline sulfatase; n=4; Bacteria|Rep: C...    91   8e-17
UniRef50_Q985M3 Cluster: Choline sulfatase; n=11; Proteobacteria...    90   1e-16
UniRef50_Q0D0R3 Cluster: Putative uncharacterized protein; n=1; ...    90   1e-16
UniRef50_Q7W424 Cluster: Putative sulfatase; n=2; Bordetella|Rep...    89   2e-16
UniRef50_Q3W0K8 Cluster: Sulfatase precursor; n=1; Frankia sp. E...    89   2e-16
UniRef50_A6DM50 Cluster: Choline sulfatase; n=3; Lentisphaera ar...    89   3e-16
UniRef50_A4W906 Cluster: Sulfatase precursor; n=10; Enterobacter...    89   3e-16
UniRef50_Q0V1P8 Cluster: Putative uncharacterized protein; n=1; ...    89   3e-16
UniRef50_Q5LRB5 Cluster: Choline sulfatase; n=1; Silicibacter po...    88   4e-16
UniRef50_A3ZTV8 Cluster: Mucin-desulfating sulfatase; n=1; Blast...    88   4e-16
UniRef50_Q15XR5 Cluster: Sulfatase precursor; n=1; Pseudoalterom...    86   2e-15
UniRef50_Q6UWY0 Cluster: Arylsulfatase K precursor; n=27; Eutele...    86   2e-15
UniRef50_UPI0000519E45 Cluster: PREDICTED: similar to glucosamin...    85   4e-15
UniRef50_A0JAV7 Cluster: Sulfatase precursor; n=1; Shewanella wo...    84   7e-15
UniRef50_Q029P1 Cluster: Sulfatase precursor; n=1; Solibacter us...    84   1e-14
UniRef50_Q01RE9 Cluster: Sulfatase precursor; n=4; Bacteria|Rep:...    84   1e-14
UniRef50_Q2U5H2 Cluster: Sulfatases; n=9; Pezizomycotina|Rep: Su...    83   1e-14
UniRef50_P15586 Cluster: N-acetylglucosamine-6-sulfatase precurs...    83   1e-14
UniRef50_Q7UH28 Cluster: Mucin-desulfating sulfatase; n=2; Bacte...    83   2e-14
UniRef50_A6DIE0 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    81   9e-14
UniRef50_Q2U8N6 Cluster: Sulfatases; n=1; Aspergillus oryzae|Rep...    81   9e-14
UniRef50_A0Q2E3 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    80   2e-13
UniRef50_A6DHW4 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    79   3e-13
UniRef50_A6C1Q0 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    79   3e-13
UniRef50_Q7UFA5 Cluster: Putative sulfatase yidj; n=1; Pirellula...    79   4e-13
UniRef50_Q28M80 Cluster: Sulfatase; n=3; Rhodobacteraceae|Rep: S...    79   4e-13
UniRef50_A6DK33 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaer...    79   4e-13
UniRef50_A4CMB1 Cluster: Arylsulphatase A; n=3; Bacteria|Rep: Ar...    79   4e-13
UniRef50_Q5UEW6 Cluster: Probable phosphonate monoester hydrolas...    78   5e-13
UniRef50_A3JPC9 Cluster: Mucin-desulfating sulfatase; n=1; Rhodo...    78   5e-13
UniRef50_A3HTC7 Cluster: Putative uncharacterized protein; n=1; ...    78   5e-13
UniRef50_A4QZC6 Cluster: Putative uncharacterized protein; n=1; ...    78   5e-13
UniRef50_Q01PN7 Cluster: Sulfatase precursor; n=1; Solibacter us...    78   6e-13
UniRef50_A6DNI8 Cluster: Putative N-acetylglucosamine-6-sulfatas...    78   6e-13
UniRef50_Q5UEW7 Cluster: Putative sulfatase; n=1; uncultured alp...    77   8e-13
UniRef50_A6DLX7 Cluster: Putative sulfatase; n=1; Lentisphaera a...    77   8e-13
UniRef50_A6UE90 Cluster: Sulfatase; n=1; Sinorhizobium medicae W...    77   1e-12
UniRef50_Q4WBJ6 Cluster: Arylsulfatase, putative; n=4; Pezizomyc...    77   1e-12
UniRef50_Q7NMX5 Cluster: Gll0640 protein; n=1; Gloeobacter viola...    77   1e-12
UniRef50_Q8IWU6 Cluster: Extracellular sulfatase Sulf-1 precurso...    77   1e-12
UniRef50_A5P718 Cluster: Calcium-binding protein; n=1; Erythroba...    76   3e-12
UniRef50_A4AQQ7 Cluster: N-acetylgalactosamine 6-sulfatase; n=4;...    75   3e-12
UniRef50_A3I0S5 Cluster: Putative sulfatase yidJ; n=1; Algoripha...    75   4e-12
UniRef50_UPI00015B4E43 Cluster: PREDICTED: similar to CG6725-PA;...    74   8e-12
UniRef50_Q7UGD6 Cluster: Mucin-desulfating sulfatase; n=1; Pirel...    74   8e-12
UniRef50_A3TPK9 Cluster: Probable phosphonate monoester hydrolas...    74   8e-12
UniRef50_A6DG38 Cluster: N-acetylglucosamine-6-sulfatase; n=1; L...    74   1e-11
UniRef50_A4FI25 Cluster: Sulfatase; n=3; Actinomycetales|Rep: Su...    73   2e-11
UniRef50_Q15NY5 Cluster: Sulfatase precursor; n=1; Pseudoalterom...    73   2e-11
UniRef50_A6DFN4 Cluster: Arylsulfatase; n=1; Lentisphaera araneo...    73   2e-11
UniRef50_A6CBI6 Cluster: Putative uncharacterized protein; n=1; ...    72   3e-11
UniRef50_Q5LKJ1 Cluster: Phosphonate monoester hydrolase, putati...    71   7e-11
UniRef50_Q15XH3 Cluster: Sulfatase precursor; n=1; Pseudoalterom...    71   7e-11
UniRef50_A6DMZ1 Cluster: Sulfatase; n=5; Lentisphaera araneosa H...    71   7e-11
UniRef50_Q8IWU5 Cluster: Extracellular sulfatase Sulf-2 precurso...    71   7e-11
UniRef50_O43113 Cluster: Arylsulfatase; n=3; Sordariales|Rep: Ar...    71   1e-10
UniRef50_A2TWV5 Cluster: N-acetylglucosamine-6-sulfatase; n=1; P...    70   1e-10
UniRef50_Q2UNM0 Cluster: Sulfatases; n=1; Aspergillus oryzae|Rep...    70   1e-10
UniRef50_A3HWG3 Cluster: Choline sulfatase; n=1; Algoriphagus sp...    70   2e-10
UniRef50_Q7UYS7 Cluster: Mucin-desulfating sulfatase; n=1; Pirel...    69   2e-10
UniRef50_A6C8U0 Cluster: Choline sulfatase; n=1; Planctomyces ma...    69   2e-10
UniRef50_A4ASQ2 Cluster: Mucin-desulfating sulfatase; n=1; Flavo...    69   2e-10
UniRef50_Q3KJU8 Cluster: Sulfatase; n=6; Proteobacteria|Rep: Sul...    69   3e-10
UniRef50_Q2JAY4 Cluster: Sulfatase precursor; n=1; Frankia sp. C...    69   3e-10
UniRef50_Q9VEX0 Cluster: Extracellular sulfatase SULF-1 homolog ...    69   3e-10
UniRef50_Q3M597 Cluster: Twin-arginine translocation pathway sig...    69   4e-10
UniRef50_A6DKP2 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    69   4e-10
UniRef50_Q8A3A3 Cluster: Mucin-desulfating sulfatase; n=4; Bacte...    68   5e-10
UniRef50_A6DFB5 Cluster: Mucin-desulfating sulfatase; n=2; Lenti...    68   5e-10
UniRef50_A6CAR8 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    68   5e-10
UniRef50_Q7UVD9 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    68   7e-10
UniRef50_Q15XI1 Cluster: Sulfatase; n=2; Bacteria|Rep: Sulfatase...    67   1e-09
UniRef50_A6CCV5 Cluster: Sulfatase; n=3; Bacteria|Rep: Sulfatase...    67   1e-09
UniRef50_A0JAV3 Cluster: Sulfatase precursor; n=1; Shewanella wo...    67   1e-09
UniRef50_A5P719 Cluster: Iduronate sulfatase; n=1; Erythrobacter...    66   2e-09
UniRef50_A4AAM5 Cluster: Sulfatase; n=1; Congregibacter litorali...    66   2e-09
UniRef50_A0Z632 Cluster: Arylsulfatase B; n=1; marine gamma prot...    66   2e-09
UniRef50_UPI0000E0EEBA Cluster: mucin-desulfating sulfatase (N-a...    66   3e-09
UniRef50_A6DRX0 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    66   3e-09
UniRef50_Q7UZ42 Cluster: Mucin-desulfating sulfatase; n=5; Bacte...    65   4e-09
UniRef50_Q12Q17 Cluster: Sulfatase; n=1; Shewanella denitrifican...    65   4e-09
UniRef50_A6DKC5 Cluster: Putative sulfatase yidj; n=1; Lentispha...    65   4e-09
UniRef50_A6DIH0 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaer...    65   4e-09
UniRef50_A6DKP3 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    65   5e-09
UniRef50_A6DTP6 Cluster: Arylsulfatase; n=1; Lentisphaera araneo...    64   6e-09
UniRef50_P50429 Cluster: Arylsulfatase B precursor; n=17; Eumeta...    64   6e-09
UniRef50_Q6SI01 Cluster: Sulfatase family protein; n=1; uncultur...    64   8e-09
UniRef50_A6DJJ7 Cluster: Arylsulfatase; n=1; Lentisphaera araneo...    64   8e-09
UniRef50_UPI00015B5C4D Cluster: PREDICTED: similar to ENSANGP000...    64   1e-08
UniRef50_A6DNH2 Cluster: Putative uncharacterized protein; n=1; ...    64   1e-08
UniRef50_A0YAF7 Cluster: Arylsulfatase A; n=1; marine gamma prot...    64   1e-08
UniRef50_Q5DYR9 Cluster: N-acetylglucosamine-6-sulfatase; n=10; ...    63   1e-08
UniRef50_Q45087 Cluster: Phosphonate monoester hydrolase; n=4; P...    63   1e-08
UniRef50_A6DHI0 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    63   1e-08
UniRef50_Q650Q8 Cluster: Arylsulfatase; n=5; Bacteria|Rep: Aryls...    63   2e-08
UniRef50_A0M223 Cluster: Sulfatase; n=1; Gramella forsetii KT080...    63   2e-08
UniRef50_A0JVM4 Cluster: Sulfatase; n=1; Arthrobacter sp. FB24|R...    63   2e-08
UniRef50_Q127E2 Cluster: Sulfatase; n=1; Polaromonas sp. JS666|R...    62   3e-08
UniRef50_A3I1P8 Cluster: Heparan N-sulfatase; n=3; Bacteria|Rep:...    62   3e-08
UniRef50_A0LYA0 Cluster: Sulfatase; n=3; Bacteria|Rep: Sulfatase...    62   3e-08
UniRef50_Q8FTJ9 Cluster: Putative arylsulfatase; n=1; Corynebact...    62   3e-08
UniRef50_A3XJJ9 Cluster: Arylsulfatase B; n=1; Leeuwenhoekiella ...    62   3e-08
UniRef50_Q1VP00 Cluster: Arylsulfatase B; n=1; Psychroflexus tor...    62   4e-08
UniRef50_A7LZQ6 Cluster: Putative uncharacterized protein; n=1; ...    62   4e-08
UniRef50_A0JVN2 Cluster: Sulfatase; n=1; Arthrobacter sp. FB24|R...    62   4e-08
UniRef50_Q7UH63 Cluster: Arylsulphatase A; n=3; Bacteria|Rep: Ar...    61   6e-08
UniRef50_A6CGG6 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    61   6e-08
UniRef50_A6CBG2 Cluster: Mucin-desulfating sulfatase; n=1; Planc...    61   6e-08
UniRef50_Q7UKJ5 Cluster: Arylsulfatase A; n=3; Bacteria|Rep: Ary...    61   8e-08
UniRef50_Q2CEI6 Cluster: Putative choline-sulfatase; n=1; Oceani...    61   8e-08
UniRef50_A0JAV5 Cluster: Sulfatase precursor; n=1; Shewanella wo...    61   8e-08
UniRef50_Q7UYS6 Cluster: Arylsulfatase A; n=3; Bacteria|Rep: Ary...    60   1e-07
UniRef50_Q7UHJ6 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    60   1e-07
UniRef50_A6DSG4 Cluster: Arylsulphatase A; n=1; Lentisphaera ara...    60   1e-07
UniRef50_A3JW99 Cluster: Putative phosphonate monoester hydrolas...    60   1e-07
UniRef50_Q18837 Cluster: Sulfatase domain protein protein 3, iso...    60   1e-07
UniRef50_UPI0000D56622 Cluster: PREDICTED: similar to CG18278-PA...    60   1e-07
UniRef50_Q4SG40 Cluster: Chromosome 12 SCAF14600, whole genome s...    60   1e-07
UniRef50_Q5UEY3 Cluster: Probable sulfatase; n=1; uncultured alp...    60   1e-07
UniRef50_A7LY81 Cluster: Putative uncharacterized protein; n=1; ...    60   1e-07
UniRef50_A6DMX8 Cluster: Iduronate-sulfatase or arylsulfatase A;...    60   1e-07
UniRef50_A6C1V3 Cluster: Putative secreted sulfatase ydeN; n=1; ...    60   1e-07
UniRef50_Q7UYD2 Cluster: Sulfatase 1; n=2; Bacteria|Rep: Sulfata...    60   2e-07
UniRef50_Q7UL93 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    60   2e-07
UniRef50_A6DR15 Cluster: Arylsulfatase; n=2; Lentisphaera araneo...    60   2e-07
UniRef50_A6DKS7 Cluster: N-acetylglucosamine-6-sulfatase; n=1; L...    60   2e-07
UniRef50_A6C430 Cluster: Arylsulphatase A; n=1; Planctomyces mar...    60   2e-07
UniRef50_A6BZT7 Cluster: Putative arylsulfatase; n=1; Planctomyc...    60   2e-07
UniRef50_A3HYT7 Cluster: Arylsulphatase A; n=1; Algoriphagus sp....    60   2e-07
UniRef50_UPI0000D55F5E Cluster: PREDICTED: similar to CG8646-PA;...    59   2e-07
UniRef50_Q3IBP8 Cluster: Sulfatase; n=1; uncultured sulfate-redu...    59   2e-07
UniRef50_A6FX65 Cluster: Probable arylsulfatase ; probable choli...    59   2e-07
UniRef50_A6DNJ0 Cluster: Sulfatase; n=1; Lentisphaera araneosa H...    59   2e-07
UniRef50_A6DJ11 Cluster: Arylsulfatase A; n=1; Lentisphaera aran...    59   2e-07
UniRef50_A3I0L2 Cluster: Arylsulfatase A; n=2; Bacteroidetes|Rep...    59   2e-07
UniRef50_A7SRP2 Cluster: Predicted protein; n=2; Nematostella ve...    59   2e-07
UniRef50_Q5V6E4 Cluster: Sulfatase; n=1; Haloarcula marismortui|...    59   2e-07
UniRef50_A5ZER6 Cluster: Putative uncharacterized protein; n=1; ...    59   3e-07
UniRef50_A3HWF8 Cluster: Mucin-desulfating sulfatase; n=4; Bacte...    59   3e-07
UniRef50_A1R7Q8 Cluster: Putative sulfatase family protein; n=1;...    59   3e-07
UniRef50_Q9HSV3 Cluster: Putative uncharacterized protein; n=1; ...    59   3e-07
UniRef50_Q5V6E3 Cluster: Putative sulfatase; n=1; Haloarcula mar...    59   3e-07
UniRef50_Q8A2F6 Cluster: Putative sulfatase yidJ; n=4; Bacteroid...    58   4e-07
UniRef50_Q89YS5 Cluster: N-acetylglucosamine-6-sulfatase; n=2; B...    58   4e-07
UniRef50_Q0VM85 Cluster: Putative uncharacterized protein; n=1; ...    58   4e-07
UniRef50_A6CBM1 Cluster: Arylsulphatase A; n=1; Planctomyces mar...    58   4e-07
UniRef50_A3ZV95 Cluster: N-acetylgalactosamine 6-sulfatase; n=3;...    58   4e-07
UniRef50_A0Q2E6 Cluster: Probable sulfatase; n=1; Clostridium no...    58   4e-07
UniRef50_A3H843 Cluster: Sulfatase; n=1; Caldivirga maquilingens...    58   4e-07
UniRef50_Q4SZ41 Cluster: Chromosome undetermined SCAF11841, whol...    58   5e-07
UniRef50_Q7UHJ9 Cluster: Iduronate-sulfatase or arylsulfatase A;...    58   5e-07
UniRef50_Q7NFU3 Cluster: Gll3431 protein; n=2; Gloeobacter viola...    58   5e-07
UniRef50_A6DG52 Cluster: Arylsulphatase A; n=1; Lentisphaera ara...    58   5e-07
UniRef50_Q9VVM1 Cluster: CG7408-PB; n=2; Drosophila melanogaster...    58   5e-07
UniRef50_Q5DYT4 Cluster: Arylsulfatase; n=10; Gammaproteobacteri...    58   7e-07
UniRef50_A6LEC5 Cluster: Arylsulfatase A; n=1; Parabacteroides d...    58   7e-07
UniRef50_A6DKM6 Cluster: Arylsulfatase A; n=1; Lentisphaera aran...    58   7e-07
UniRef50_Q2UHR5 Cluster: Arylsulfatase A and related enzymes; n=...    58   7e-07
UniRef50_A6DGX5 Cluster: N-acetylgalactosamine 6-sulfatase; n=2;...    57   1e-06
UniRef50_A6DF72 Cluster: Putative secreted sulfatase ydeN; n=1; ...    57   1e-06
UniRef50_A6CEL4 Cluster: Arylsulfatase A; n=1; Planctomyces mari...    57   1e-06
UniRef50_A6CAW6 Cluster: N-acetylgalactosamine-4-sulfatase; n=1;...    57   1e-06
UniRef50_A4AM21 Cluster: Arylsulfatase A; n=2; Bacteroidetes|Rep...    57   1e-06
UniRef50_A4CMB0 Cluster: Arylsulfatase A; n=5; Bacteria|Rep: Ary...    57   1e-06
UniRef50_Q21376 Cluster: Putative extracellular sulfatase Sulf-1...    57   1e-06
UniRef50_Q7UYA9 Cluster: N-acetylgalactosamine-6-sulfatase; n=1;...    56   2e-06
UniRef50_Q482D6 Cluster: Sulfatase family protein; n=2; Bacteria...    56   2e-06
UniRef50_Q15US7 Cluster: Sulfatase; n=2; Bacteria|Rep: Sulfatase...    56   2e-06
UniRef50_A6E7U2 Cluster: Putative exported sulfatase; n=1; Pedob...    56   2e-06
UniRef50_A5YSA6 Cluster: Probable arylsulfatase; n=2; Halobacter...    56   2e-06
UniRef50_P34059 Cluster: N-acetylgalactosamine-6-sulfatase precu...    56   2e-06
UniRef50_UPI0000586CBA Cluster: PREDICTED: similar to arylsulfat...    56   2e-06
UniRef50_Q4RJR3 Cluster: Chromosome 13 SCAF15035, whole genome s...    56   2e-06
UniRef50_Q8DBM0 Cluster: Predicted hydrolase of alkaline phospha...    56   2e-06
UniRef50_Q576E2 Cluster: Sulfatase; n=6; Rhizobiales|Rep: Sulfat...    56   2e-06
UniRef50_A6LIT7 Cluster: Mucin-desulfating sulfatase MdsA; n=1; ...    56   2e-06
UniRef50_A6DQV3 Cluster: Sulfatase; n=1; Lentisphaera araneosa H...    56   2e-06
UniRef50_A6DKB8 Cluster: N-acetylgalactosamine 6-sulfatase; n=3;...    56   2e-06
UniRef50_A0IXQ1 Cluster: Sulfatase precursor; n=1; Shewanella wo...    56   2e-06
UniRef50_P31447 Cluster: Uncharacterized sulfatase yidJ; n=11; E...    56   2e-06
UniRef50_Q98FN9 Cluster: Phosphonate monoester hydrolase; n=4; A...    56   3e-06
UniRef50_Q7UIN2 Cluster: Probable sulfatase; n=2; Bacteria|Rep: ...    56   3e-06
UniRef50_Q64P90 Cluster: Putative secreted sulfatase ydeN; n=2; ...    56   3e-06
UniRef50_A6DU75 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    56   3e-06
UniRef50_A6DTI5 Cluster: Probable sulfatase; n=1; Lentisphaera a...    56   3e-06
UniRef50_A6DRV5 Cluster: Arylsulfatase A; n=1; Lentisphaera aran...    56   3e-06
UniRef50_A6DM48 Cluster: Arylsulfatase A; n=1; Lentisphaera aran...    56   3e-06
UniRef50_A6C4Q9 Cluster: Arylsulphatase A; n=1; Planctomyces mar...    56   3e-06
UniRef50_A0JVM5 Cluster: Sulfatase; n=1; Arthrobacter sp. FB24|R...    56   3e-06
UniRef50_A7S8Q2 Cluster: Predicted protein; n=2; Nematostella ve...    56   3e-06
UniRef50_Q7UYW2 Cluster: Arylsulfatase; n=2; Planctomycetaceae|R...    55   4e-06
UniRef50_A6DPC8 Cluster: Arylsulfatase A; n=1; Lentisphaera aran...    55   4e-06
UniRef50_A6DJ15 Cluster: Putative arylsulfatase; n=2; Lentisphae...    55   4e-06
UniRef50_A6C284 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    55   4e-06
UniRef50_A3J5W3 Cluster: Putative arylsulfatase; n=1; Flavobacte...    55   4e-06
UniRef50_Q7UPG6 Cluster: Arylsulphatase A; n=2; Bacteria|Rep: Ar...    55   5e-06
UniRef50_Q1VDY3 Cluster: Probable sulfatase; n=1; Vibrio alginol...    55   5e-06
UniRef50_A6DU78 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    55   5e-06
UniRef50_A6DFG8 Cluster: Arylsulphatase A; n=1; Lentisphaera ara...    55   5e-06
UniRef50_A6C3C8 Cluster: Putative uncharacterized protein; n=1; ...    55   5e-06
UniRef50_Q7UYA5 Cluster: Arylsulfatase; n=1; Pirellula sp.|Rep: ...    54   7e-06
UniRef50_A6DMY9 Cluster: Putative uncharacterized protein; n=2; ...    54   7e-06
UniRef50_A6DHI1 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    54   7e-06
UniRef50_A6DGD3 Cluster: Putative exported uslfatase; n=3; Bacte...    54   7e-06
UniRef50_A6DF77 Cluster: Arylsulphatase A; n=2; Lentisphaera ara...    54   7e-06
UniRef50_A4ANB9 Cluster: Probable sulfatase; n=1; Flavobacterial...    54   7e-06
UniRef50_Q5KJE5 Cluster: Arylsulfatase, putative; n=2; Filobasid...    54   7e-06
UniRef50_Q8A168 Cluster: Putative sulfatase yidJ; n=5; Bacteroid...    54   9e-06
UniRef50_Q9L5W0 Cluster: Mucin-desulfating sulfatase MdsA precur...    54   9e-06
UniRef50_A6DKN7 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    54   9e-06
UniRef50_A6CBU4 Cluster: Sulfatase; n=1; Planctomyces maris DSM ...    54   9e-06
UniRef50_A6C383 Cluster: Sulfatase; n=1; Planctomyces maris DSM ...    54   9e-06
UniRef50_A4CGL5 Cluster: Arylsulfatase A; n=4; Bacteria|Rep: Ary...    54   9e-06
UniRef50_A1WGF5 Cluster: Sulfatase; n=2; Proteobacteria|Rep: Sul...    54   9e-06
UniRef50_A0J704 Cluster: Sulfatase precursor; n=1; Shewanella wo...    54   9e-06
UniRef50_Q02AN8 Cluster: Sulfatase precursor; n=1; Solibacter us...    54   1e-05
UniRef50_A7HW45 Cluster: Sulfatase; n=1; Parvibaculum lavamentiv...    54   1e-05
UniRef50_A6DNW5 Cluster: Arylsulfatase; n=1; Lentisphaera araneo...    54   1e-05
UniRef50_A6DMX7 Cluster: N-acetyl-galactosamine-6-sulfatase; n=1...    54   1e-05
UniRef50_A6DLY1 Cluster: Putative sulfatase; n=1; Lentisphaera a...    54   1e-05
UniRef50_A3ZVD1 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    54   1e-05
UniRef50_A3HRL2 Cluster: Probable sulfatase atsG; n=1; Algoripha...    54   1e-05
UniRef50_P51690 Cluster: Arylsulfatase E precursor; n=7; Mammali...    54   1e-05
UniRef50_UPI0000ECD579 Cluster: UPI0000ECD579 related cluster; n...    53   2e-05
UniRef50_Q0BAJ7 Cluster: Sulfatase; n=9; Proteobacteria|Rep: Sul...    53   2e-05
UniRef50_UPI0000E49A98 Cluster: PREDICTED: similar to ENSANGP000...    53   2e-05
UniRef50_UPI0000E0F7C6 Cluster: N-sulphoglucosamine sulphohydrol...    53   2e-05
UniRef50_UPI000023EB95 Cluster: hypothetical protein FG11130.1; ...    53   2e-05
UniRef50_Q5UEW3 Cluster: Putative sulfatase; n=1; uncultured alp...    53   2e-05
UniRef50_Q1ARG1 Cluster: Sulfatase precursor; n=2; Rubrobacter x...    53   2e-05
UniRef50_Q15SA2 Cluster: Sulfatase precursor; n=1; Pseudoalterom...    53   2e-05
UniRef50_A6EGE7 Cluster: N-acetylgalactosamine-6-sulfatase; n=3;...    53   2e-05
UniRef50_A6DRW5 Cluster: Putative sulfatase; n=2; Lentisphaera a...    53   2e-05
UniRef50_A6DR20 Cluster: N-acetyl-galactosamine-6-sulfatase; n=1...    53   2e-05
UniRef50_Q7UH85 Cluster: N-acetylgalactosamine-6-sulfatase; n=1;...    52   3e-05
UniRef50_A6DR17 Cluster: Probable arylsulfatase A; n=1; Lentisph...    52   3e-05
UniRef50_A6CGJ7 Cluster: Sulfatase; n=1; Planctomyces maris DSM ...    52   3e-05
UniRef50_A4FJ34 Cluster: Sulfatase; n=1; Saccharopolyspora eryth...    52   3e-05
UniRef50_UPI0000EBF0AD Cluster: PREDICTED: similar to arylsulfat...    52   4e-05
UniRef50_Q7UPK7 Cluster: Arylsulphatase A; n=1; Pirellula sp.|Re...    52   4e-05
UniRef50_Q5E4A1 Cluster: Phosphoglycerol transferase MdoB and re...    52   4e-05
UniRef50_Q0BZE9 Cluster: Sulfatase family protein; n=1; Hyphomon...    52   4e-05
UniRef50_A6DS95 Cluster: Arylsulfatase A; n=2; Lentisphaera aran...    52   4e-05
UniRef50_A6DFS2 Cluster: N-acetylgalactosamine-6-sulfatase; n=1;...    52   4e-05
UniRef50_A6CGJ8 Cluster: Arylsulfatase A; n=1; Planctomyces mari...    52   4e-05
UniRef50_A3HXL4 Cluster: Heparan N-sulfatase; n=1; Algoriphagus ...    52   4e-05
UniRef50_A0GIT5 Cluster: Sulfatase; n=5; Burkholderiales|Rep: Su...    52   4e-05
UniRef50_Q9VVM4 Cluster: CG7402-PA; n=3; Diptera|Rep: CG7402-PA ...    52   4e-05
UniRef50_P15289 Cluster: Arylsulfatase A precursor (EC 3.1.6.8) ...    52   4e-05
UniRef50_Q8A346 Cluster: Arylsulfatase A; n=12; Bacteria|Rep: Ar...    52   5e-05
UniRef50_Q1GUE2 Cluster: Sulfatase precursor; n=3; Bacteria|Rep:...    52   5e-05
UniRef50_A6DLR4 Cluster: Probable sulfatase atsG; n=1; Lentispha...    52   5e-05
UniRef50_A6DFU7 Cluster: Mucin-desulfating sulfatase; n=1; Lenti...    52   5e-05
UniRef50_Q16YZ8 Cluster: Sulfatase-1, sulf-1; n=1; Aedes aegypti...    52   5e-05
UniRef50_A7RFN2 Cluster: Predicted protein; n=2; Nematostella ve...    52   5e-05
UniRef50_Q4WZA7 Cluster: Sulfatase domain protein; n=3; Trichoco...    52   5e-05
UniRef50_Q7UGD7 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    51   6e-05
UniRef50_Q5LVA2 Cluster: Choline sulfatase, putative; n=1; Silic...    51   6e-05
UniRef50_A6LED1 Cluster: Arylsulfatase A; n=1; Parabacteroides d...    51   6e-05
UniRef50_A6GK09 Cluster: Sulfatase; n=1; Plesiocystis pacifica S...    51   6e-05
UniRef50_A6CDF9 Cluster: Heparan N-sulfatase; n=1; Planctomyces ...    51   6e-05
UniRef50_A6C781 Cluster: Putative sulfatase; n=1; Planctomyces m...    51   6e-05
UniRef50_A4AQQ8 Cluster: Sulfatase family protein; n=1; Flavobac...    51   6e-05
UniRef50_Q17B03 Cluster: Arylsulfatase b; n=3; Culicidae|Rep: Ar...    51   6e-05
UniRef50_A7SPY2 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ...    51   6e-05
UniRef50_Q0TS43 Cluster: Sulfatase family protein; n=1; Clostrid...    51   8e-05
UniRef50_A6LDP6 Cluster: Arylsulfatase A; n=1; Parabacteroides d...    51   8e-05
UniRef50_A6DG79 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    51   8e-05
UniRef50_Q8IQS4 Cluster: CG32191-PA; n=2; Sophophora|Rep: CG3219...    51   8e-05
UniRef50_Q2UB95 Cluster: Predicted protein; n=4; Trichocomaceae|...    51   8e-05
UniRef50_UPI0000E484C0 Cluster: PREDICTED: similar to arylsulfat...    50   1e-04
UniRef50_UPI0000D55D4D Cluster: PREDICTED: similar to CG8646-PA;...    50   1e-04
UniRef50_Q7UYH4 Cluster: Arylsulfatase; n=1; Pirellula sp.|Rep: ...    50   1e-04
UniRef50_Q7US96 Cluster: Arylsulphatase A; n=1; Pirellula sp.|Re...    50   1e-04
UniRef50_Q7UIN1 Cluster: Arylsulfatase A; n=2; cellular organism...    50   1e-04
UniRef50_Q7TXB2 Cluster: POSSIBLE HYDROLASE; n=15; Mycobacterium...    50   1e-04
UniRef50_Q1Q487 Cluster: Putative uncharacterized protein; n=1; ...    50   1e-04
UniRef50_Q1PWI3 Cluster: Putative uncharacterized protein; n=1; ...    50   1e-04
UniRef50_A6DSH3 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    50   1e-04
UniRef50_A6DPE4 Cluster: Arylsulfatase; n=1; Lentisphaera araneo...    50   1e-04
UniRef50_A6ARG0 Cluster: Sulfatase domain protein; n=6; Vibrio|R...    50   1e-04
UniRef50_Q5V6X5 Cluster: Sulfatase; n=1; Haloarcula marismortui|...    50   1e-04
UniRef50_UPI0000E0F7DD Cluster: aryl-sulphate sulphohydrolase; n...    50   1e-04
UniRef50_UPI0000D56522 Cluster: PREDICTED: similar to CG7402-PA;...    50   1e-04
UniRef50_Q64MS8 Cluster: Arylsulfatase; n=7; Bacteria|Rep: Aryls...    50   1e-04
UniRef50_Q1YP24 Cluster: Arylsulfatase A; n=1; gamma proteobacte...    50   1e-04
UniRef50_Q01TB1 Cluster: Sulfatase; n=1; Solibacter usitatus Ell...    50   1e-04
UniRef50_A6V872 Cluster: Arylsulfatase; n=1; Pseudomonas aerugin...    50   1e-04
UniRef50_A6DSG7 Cluster: Sulfatase; n=1; Lentisphaera araneosa H...    50   1e-04
UniRef50_A6CFY9 Cluster: Arylsulfatase; n=2; Bacteria|Rep: Aryls...    50   1e-04
UniRef50_A6CD52 Cluster: Twin-arginine translocation pathway sig...    50   1e-04
UniRef50_A6C3Y0 Cluster: Heparan N-sulfatase; n=2; Bacteria|Rep:...    50   1e-04
UniRef50_Q4SI19 Cluster: Chromosome 5 SCAF14581, whole genome sh...    50   2e-04
UniRef50_Q8A2X8 Cluster: Mucin-desulfating sulfatase; n=13; Bact...    50   2e-04
UniRef50_Q7UHK0 Cluster: Arylsulphatase A; n=1; Pirellula sp.|Re...    50   2e-04
UniRef50_A6DPD1 Cluster: Probable sulfatase atsG; n=1; Lentispha...    50   2e-04
UniRef50_A6DMW2 Cluster: Putative exported uslfatase; n=1; Lenti...    50   2e-04
UniRef50_A6DMV0 Cluster: N-acetylgalactosamine-6-sulfate sulfata...    50   2e-04
UniRef50_A6DGX8 Cluster: Heparan N-sulfatase; n=1; Lentisphaera ...    50   2e-04
UniRef50_A5ZEH0 Cluster: Putative uncharacterized protein; n=2; ...    50   2e-04
UniRef50_A5FAX9 Cluster: Sulfatase precursor; n=1; Flavobacteriu...    50   2e-04
UniRef50_Q8TMK7 Cluster: Arylsulfatase; n=5; cellular organisms|...    50   2e-04
UniRef50_Q7UYD6 Cluster: N-acetyl-galactosamine-6-sulfatase; n=3...    49   3e-04
UniRef50_Q7UYC3 Cluster: Heparan N-sulfatase; n=1; Pirellula sp....    49   3e-04
UniRef50_Q7UYA6 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    49   3e-04
UniRef50_Q7UT91 Cluster: Probable sulfatase; n=2; Planctomycetac...    49   3e-04
UniRef50_Q2CEJ3 Cluster: Probable sulfatase; n=1; Oceanicola gra...    49   3e-04
UniRef50_Q15SD1 Cluster: Sulfatase precursor; n=1; Pseudoalterom...    49   3e-04
UniRef50_Q061A4 Cluster: Putative sulfatase; n=1; Synechococcus ...    49   3e-04
UniRef50_A7HWE6 Cluster: Sulfatase; n=1; Parvibaculum lavamentiv...    49   3e-04
UniRef50_A6GAT7 Cluster: Probable arylsulfatase ; probable choli...    49   3e-04
UniRef50_A6DMW0 Cluster: Arylsulphatase A; n=1; Lentisphaera ara...    49   3e-04
UniRef50_A6DGK3 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    49   3e-04
UniRef50_A4GIB0 Cluster: Heparan N-sulfatase; n=1; uncultured ma...    49   3e-04
UniRef50_A3ZLD4 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    49   3e-04
UniRef50_A3HZ22 Cluster: Putative exported uslfatase; n=1; Algor...    49   3e-04
UniRef50_Q2UDW4 Cluster: Beta-glucosidase-related glycosidases; ...    49   3e-04
UniRef50_Q3JD43 Cluster: Sulfatase; n=1; Nitrosococcus oceani AT...    49   3e-04
UniRef50_Q1AXQ7 Cluster: Sulfatase; n=2; Rubrobacter xylanophilu...    49   3e-04
UniRef50_A6DLW9 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    49   3e-04
UniRef50_A6DIG7 Cluster: Iduronate-sulfatase or arylsulfatase A;...    49   3e-04
UniRef50_A6C9Y6 Cluster: Heparan N-sulfatase; n=1; Planctomyces ...    49   3e-04
UniRef50_A5FF56 Cluster: Sulfatase precursor; n=2; Bacteria|Rep:...    49   3e-04
UniRef50_UPI0000E47BCC Cluster: PREDICTED: similar to arylsulfat...    48   4e-04
UniRef50_UPI000023D70F Cluster: hypothetical protein FG03321.1; ...    48   4e-04
UniRef50_Q4SR77 Cluster: Chromosome 11 SCAF14528, whole genome s...    48   4e-04
UniRef50_Q64YV7 Cluster: Arylsulfatase; n=4; Bacteroides fragili...    48   4e-04
UniRef50_Q2GB51 Cluster: Sulfatase; n=2; Proteobacteria|Rep: Sul...    48   4e-04
UniRef50_Q7DA28 Cluster: Sulfatase family protein; n=15; Coryneb...    48   4e-04
UniRef50_Q1YSH0 Cluster: Sulfatase family protein; n=4; cellular...    48   4e-04
UniRef50_Q02B50 Cluster: Sulfatase precursor; n=1; Solibacter us...    48   4e-04
UniRef50_A6DQW6 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    48   4e-04
UniRef50_A6DNH3 Cluster: Probable sulfatase; n=1; Lentisphaera a...    48   4e-04
UniRef50_A6DJ10 Cluster: Heparan N-sulfatase; n=1; Lentisphaera ...    48   4e-04
UniRef50_A6C283 Cluster: Putative uncharacterized protein; n=1; ...    48   4e-04
UniRef50_A4GIB2 Cluster: Putative secreted sulfatase; n=1; uncul...    48   4e-04
UniRef50_A3ZUT0 Cluster: Arylsulphatase A; n=1; Blastopirellula ...    48   4e-04
UniRef50_A2QM68 Cluster: Contig An07c0020, complete genome; n=2;...    48   4e-04
UniRef50_A7DQW5 Cluster: Sulfatase; n=1; Candidatus Nitrosopumil...    48   4e-04
UniRef50_UPI0000E1104B Cluster: N-acetylgalactosamine 6-sulfate ...    48   6e-04
UniRef50_Q488C5 Cluster: Arylsulfatase; n=1; Colwellia psychrery...    48   6e-04
UniRef50_A6DID7 Cluster: Aryl-sulphate sulphohydrolase; n=2; Len...    48   6e-04
UniRef50_A6DG53 Cluster: Arylsulfatase A; n=1; Lentisphaera aran...    48   6e-04
UniRef50_A4AVA7 Cluster: Aryl-sulphate sulphohydrolase; n=2; Bac...    48   6e-04
UniRef50_A3M3B5 Cluster: Arylsulfatase; n=1; Acinetobacter bauma...    48   6e-04
UniRef50_P51689 Cluster: Arylsulfatase D precursor; n=55; Eutele...    48   6e-04
UniRef50_Q8A349 Cluster: Arylsulfatase; n=1; Bacteroides thetaio...    48   8e-04
UniRef50_P95059 Cluster: POSSIBLE ARYLSULFATASE ATSA; n=21; Acti...    48   8e-04
UniRef50_Q1D6U8 Cluster: Sulfatase family protein; n=1; Myxococc...    48   8e-04
UniRef50_Q08N44 Cluster: Arylsulfatase, putative; n=1; Stigmatel...    48   8e-04
UniRef50_Q01N83 Cluster: Sulfatase precursor; n=1; Solibacter us...    48   8e-04
UniRef50_A6BYQ3 Cluster: Mucin-desulfating sulfatase; n=1; Planc...    48   8e-04
UniRef50_Q8MVP8 Cluster: Arylsulfatase-like protein; n=1; Bolten...    48   8e-04
UniRef50_A4WHU2 Cluster: Sulfatase; n=1; Pyrobaculum arsenaticum...    48   8e-04
UniRef50_UPI0000E11058 Cluster: sulfatase family protein; n=1; a...    47   0.001
UniRef50_UPI00015A4EBD Cluster: UPI00015A4EBD related cluster; n...    47   0.001
UniRef50_Q4JLJ4 Cluster: Lr1145; n=16; Lactobacillales|Rep: Lr11...    47   0.001
UniRef50_A6DPE1 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    47   0.001
UniRef50_A6DI18 Cluster: Arylsulfatase A; n=2; Lentisphaera aran...    47   0.001
UniRef50_A4AP83 Cluster: Putative sulfatase; n=1; Flavobacterial...    47   0.001
UniRef50_A3GTL0 Cluster: Sulfatase domain protein; n=15; Vibrio ...    47   0.001
UniRef50_A2PMY0 Cluster: Sulfatase, putative; n=20; Vibrio|Rep: ...    47   0.001
UniRef50_Q18EJ4 Cluster: Probable arylsulfatase; n=1; Haloquadra...    47   0.001
UniRef50_P77318 Cluster: Uncharacterized sulfatase ydeN precurso...    47   0.001
UniRef50_Q7UQ05 Cluster: Arylsulfatase A; n=2; Planctomycetaceae...    47   0.001
UniRef50_Q7UM38 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;...    47   0.001
UniRef50_Q7UIU1 Cluster: Arylsulfatase A; n=1; Pirellula sp.|Rep...    47   0.001
UniRef50_Q2GAZ3 Cluster: Sulfatase precursor; n=1; Novosphingobi...    47   0.001
UniRef50_A6UB71 Cluster: Sulfatase; n=2; Sinorhizobium|Rep: Sulf...    47   0.001
UniRef50_A6DG78 Cluster: Sulfatase; n=1; Lentisphaera araneosa H...    47   0.001
UniRef50_A4A2W0 Cluster: Arylsulfatase A; n=1; Blastopirellula m...    47   0.001
UniRef50_A0Z718 Cluster: Twin-arginine translocation pathway sig...    47   0.001
UniRef50_Q59EB1 Cluster: N-sulfoglucosamine sulfohydrolase (Sulf...    47   0.001
UniRef50_Q6CQ28 Cluster: Similar to sp|Q8D522 Vibrio vulnificus ...    47   0.001
UniRef50_A3HAJ5 Cluster: Sulfatase; n=1; Caldivirga maquilingens...    47   0.001
UniRef50_P51688 Cluster: N-sulphoglucosamine sulphohydrolase pre...    47   0.001
UniRef50_UPI00015A6252 Cluster: Arylsulfatase E precursor (EC 3....    46   0.002
UniRef50_Q7UYW3 Cluster: Arylsulfatase B; n=1; Pirellula sp.|Rep...    46   0.002
UniRef50_Q7UUA9 Cluster: N-acetylgalactosamine 6-sulfatase; n=2;...    46   0.002
UniRef50_Q7URY7 Cluster: Aryl-sulphate sulphohydrolase; n=1; Pir...    46   0.002
UniRef50_Q3JEL9 Cluster: Arylsulfatase A and related enzymes pre...    46   0.002
UniRef50_Q1D3T4 Cluster: Sulfatase family protein; n=1; Myxococc...    46   0.002
UniRef50_A6U8K1 Cluster: Sulfatase; n=4; cellular organisms|Rep:...    46   0.002
UniRef50_A6LHS9 Cluster: Arylsulfatase; n=4; Bacteroidetes|Rep: ...    46   0.002
UniRef50_A6GRW2 Cluster: Probable arylsulfatase; n=1; Limnobacte...    46   0.002
UniRef50_A6DSG9 Cluster: Sulfatase; n=2; Lentisphaera araneosa H...    46   0.002
UniRef50_A6DPC9 Cluster: Arylsulphatase A; n=1; Lentisphaera ara...    46   0.002
UniRef50_A0WZ00 Cluster: Sulfatase; n=1; Shewanella pealeana ATC...    46   0.002
UniRef50_Q8SZ72 Cluster: RE14504p; n=9; Eumetazoa|Rep: RE14504p ...    46   0.002
UniRef50_UPI0000D56521 Cluster: PREDICTED: similar to CG7402-PA;...    46   0.002
UniRef50_Q7UGA0 Cluster: N-acetylgalactosamine 6-sulfate sulfata...    46   0.002
UniRef50_A6G3A3 Cluster: Sulfatase; n=1; Plesiocystis pacifica S...    46   0.002
UniRef50_A6DR14 Cluster: Heparan N-sulfatase; n=2; Lentisphaera ...    46   0.002
UniRef50_A6DQE3 Cluster: Arylsulfatase A; n=1; Lentisphaera aran...    46   0.002
UniRef50_A6DJ57 Cluster: Arylsulphatase A; n=2; Lentisphaera ara...    46   0.002
UniRef50_A6DG39 Cluster: Arylsulfatase; n=1; Lentisphaera araneo...    46   0.002
UniRef50_A6CEG5 Cluster: Arylsulphatase A; n=2; Bacteria|Rep: Ar...    46   0.002
UniRef50_A3ZMN6 Cluster: Arylsulfatase B; n=1; Blastopirellula m...    46   0.002
UniRef50_Q86W75 Cluster: ARSK protein; n=1; Homo sapiens|Rep: AR...    46   0.002
UniRef50_Q18EH8 Cluster: Probable sulfatase; n=1; Haloquadratum ...    46   0.002
UniRef50_UPI0000588E05 Cluster: PREDICTED: similar to steroid su...    46   0.003
UniRef50_Q8D520 Cluster: Arylsulfatase A; n=2; Vibrio vulnificus...    46   0.003
UniRef50_Q47Q78 Cluster: N-acetylgalactosamine-6-sulfate sulfata...    46   0.003

>UniRef50_Q4V5Y6 Cluster: IP11830p; n=10; Endopterygota|Rep:
           IP11830p - Drosophila melanogaster (Fruit fly)
          Length = 516

 Score =  459 bits (1131), Expect = e-128
 Identities = 229/492 (46%), Positives = 319/492 (64%), Gaps = 19/492 (3%)

Query: 25  NILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N++ ++ DDLR +     D     P ++   +    F   ++QQ+LCAPSRNSLLTGRRP
Sbjct: 30  NVVMVIFDDLRPVIGAYGDTLASTPYLDNFARGSHIFTRVYSQQSLCAPSRNSLLTGRRP 89

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
           D+L LYDFYSYWR  +   GNFTT+PQ+FKEHGY TYS GKVFHPG SSN TDDYP SWS
Sbjct: 90  DTLHLYDFYSYWRTFT---GNFTTLPQYFKEHGYYTYSCGKVFHPGLSSNNTDDYPLSWS 146

Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL--KK 198
              + P TE + ++ VC +K+   L +NLICPV ++ QP ++LPD++S+  A+ F+  + 
Sbjct: 147 APAFRPRTEQFMNSPVCPDKEGI-LRKNLICPVELQTQPYKTLPDIESVAEALRFVGSRS 205

Query: 199 RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNI-PKDMPLVSWHPWTDVR 257
           R+  +PFFLA+GFHKPHI  +FP+++L +  +S+ +   E ++ P DMP V+W+P+TDVR
Sbjct: 206 RHSQEPFFLAMGFHKPHINFRFPRQFLSRFNLSQFYNYTEDSLKPPDMPAVAWNPYTDVR 265

Query: 258 KRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDH 317
            RDD +  NI+FP+G +      +IRQSYYA+  Y+D+L G L+  +D+ +T++V   DH
Sbjct: 266 ARDDFKHSNISFPYGPISPLQAAQIRQSYYASVSYVDDLFGKLIGGLDLDETVVVALGDH 325

Query: 318 GWSLGENGLWAKYSNFDYALKVPLIFKSPKL---IPTVVHEPVELIDIFPTLVDLTKLSD 374
           GWSLGE+  WAKYSNF+ AL+VPLI +SP+         H   EL+D+FPTLVDL  L  
Sbjct: 326 GWSLGEHAEWAKYSNFEVALRVPLIIRSPQFPVAQTKYYHGITELLDVFPTLVDLAGL-P 384

Query: 375 EIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQK--NSDKPRLKD 432
           ++ KC + ++ +  C EGKSL   +       E  A+SQ PRP + P K  NSDKP+L++
Sbjct: 385 KLDKCQSSQELT--CGEGKSLYHQLMGLGRADEHVALSQYPRPGMLPTKHPNSDKPKLRN 442

Query: 433 ITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKNI 492
           I IMGYS+RT  YRYT W+              YG ELYDH +D  E  NL  + ++ ++
Sbjct: 443 IKIMGYSLRTDIYRYTMWVRFHAQNFSRDWHDVYGEELYDHRLDSGEELNLVPLPQFDDV 502

Query: 493 AKVLSIRLRSSV 504
            + L  RL   V
Sbjct: 503 RQRLRRRLMEMV 514


>UniRef50_UPI00015B5B4A Cluster: PREDICTED: similar to iduronate
           2-sulfatase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to iduronate 2-sulfatase - Nasonia vitripennis
          Length = 530

 Score =  452 bits (1115), Expect = e-126
 Identities = 229/497 (46%), Positives = 316/497 (63%), Gaps = 36/497 (7%)

Query: 25  NILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+L +++DDLR      +D K + PN++ L +    F+ A+AQQALCAPSRNSLLT RRP
Sbjct: 22  NVLLVIVDDLRPALGCYNDPKAFTPNMDRLAERSVLFDKAYAQQALCAPSRNSLLTSRRP 81

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
           D+L LYDFYSYWR  +   GNFTT+PQ FK +GY T S+GKVFHPG SSN  DD PYSWS
Sbjct: 82  DTLGLYDFYSYWRKVA---GNFTTLPQHFKSNGYTTASLGKVFHPGASSNGNDDSPYSWS 138

Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRN 200
           E P+HP T+ YKDA VC  + +     NL+CPV V   P  +LPD+++L+ A  FL   N
Sbjct: 139 EKPFHPQTDRYKDAPVCGTRSSSPAS-NLVCPVRVSSMPNSTLPDIETLNAAKAFLSG-N 196

Query: 201 GSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRD 260
             +PFFLA+GF KPHIPLK+P+ +LK  P++K   PK    P ++  V+++PWTD+R+R 
Sbjct: 197 RREPFFLAVGFQKPHIPLKYPRRFLKYHPLTKFSVPKNYEWPLNVSSVAYNPWTDLRRRS 256

Query: 261 DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSD 316
           D+ +L +  P+  +P  +  +I QSYYAA  Y+D+L+G LL+ ++    M  T+++LTSD
Sbjct: 257 DVEKLGLECPWEKIPQDYGRRIIQSYYAAVTYVDDLVGDLLNELERLHLMNHTVVILTSD 316

Query: 317 HGWSLGENGLWAKYSNFDYALKVPLIFKSP----------------KLIPTVVHEPVELI 360
           HGWSLGE+  WAKYSN++ AL+VPL+   P                +L   +V EPVEL+
Sbjct: 317 HGWSLGEHAEWAKYSNYEVALRVPLLISIPNITFRVNDKFESSDYCRLQSMIVQEPVELL 376

Query: 361 DIFPTLVDLTKLS-DEIPKCLNHKDTSQLCFEGKSLVPFIEN----NSNGLEAFAISQCP 415
           DIFPT+ +L  +     P  ++H   S LC EG SLVP I+      S   +  AISQ P
Sbjct: 377 DIFPTVAELANVKISTCPNEISHSRISDLCTEGSSLVPLIKAALTCKSVPWKIGAISQYP 436

Query: 416 RPSVYP--QKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDH 473
           RP + P  + +SD+PRL++I IMGY++RT RYRYT W+              +  E+YDH
Sbjct: 437 RPGLQPSCKPSSDEPRLREIRIMGYTLRTLRYRYTAWVGFSPITKTPDWREIFAEEMYDH 496

Query: 474 IIDPIESKNLFLVSKYK 490
            ID  E+ N+    +++
Sbjct: 497 KIDQEENINVAYSKRFE 513


>UniRef50_UPI0000ECC490 Cluster: Iduronate 2-sulfatase precursor (EC
           3.1.6.13) (Alpha-L-iduronate sulfate sulfatase)
           (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa
           chain; Iduronate 2-sulfatase 14 kDa chain].; n=2; Gallus
           gallus|Rep: Iduronate 2-sulfatase precursor (EC
           3.1.6.13) (Alpha-L-iduronate sulfate sulfatase)
           (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa
           chain; Iduronate 2-sulfatase 14 kDa chain]. - Gallus
           gallus
          Length = 525

 Score =  437 bits (1077), Expect = e-121
 Identities = 232/510 (45%), Positives = 311/510 (60%), Gaps = 55/510 (10%)

Query: 25  NILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+LFI++DDLR +     D  V  PNI+ L      F+NA+AQQA+CAPSR S LTGRRP
Sbjct: 3   NVLFIVVDDLRPVLGCYGDNLVKSPNIDQLASQSIVFSNAYAQQAVCAPSRVSFLTGRRP 62

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
           D+ RLYDFYSYWR  S   GN++T+PQ+FKE+GY T SVGKVFHPG SSN++DDYPYSWS
Sbjct: 63  DTTRLYDFYSYWRVHS---GNYSTMPQYFKENGYVTMSVGKVFHPGISSNYSDDYPYSWS 119

Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRN 200
             P+HP TE Y++ K CR K  + L  NL+CP+ V   PG +LPD+++ + AI  L    
Sbjct: 120 IPPFHPSTEKYENDKTCRGKDGR-LYANLVCPIDVTEMPGGTLPDIETTEEAIRLLNVMK 178

Query: 201 GSKP-FFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR 259
             K  FFLA+G+HKPHIPL++P+E+LK  P+  +    +P +P+ +P V+++PW D+R+R
Sbjct: 179 TKKQKFFLAVGYHKPHIPLRYPQEFLKLYPLENITLAPDPWVPEKLPPVAYNPWVDIRQR 238

Query: 260 DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTS 315
           DD++ LN+TFP+G +P  +   IRQSYYAA  Y+D  +G+LL+ +D       TI+V T+
Sbjct: 239 DDVKALNVTFPYGPLPDDFQRLIRQSYYAAVSYLDMQVGLLLNALDYVGLSNSTIVVFTA 298

Query: 316 DHGWSLGENGLWAKYSNFDYALKVPLIFKSPK------------------------LIPT 351
           DHGWSLGE+G WAKYSNFD A +VPL+F  P+                        L+P 
Sbjct: 299 DHGWSLGEHGEWAKYSNFDVATQVPLMFYVPRMTTSSASQGERVFPYLDPFSHIVGLVPQ 358

Query: 352 VVHEP-VELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPF-------IENNS 403
              +  VEL+ +F TL +L  L    P C        LC EG S+V +       ++   
Sbjct: 359 GQRKKMVELVSLFSTLAELAGLQVP-PACPETSFHVALCTEGASIVRYFKSSEQKVQKKE 417

Query: 404 NGL---------EAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXX 454
           NG          E  A SQ PRP+  PQ +SDKP+LKDI IMGYS+RT  YRYT W+   
Sbjct: 418 NGCNDTNKYYSEEPVAFSQYPRPADTPQWDSDKPKLKDIRIMGYSMRTIDYRYTVWVQFN 477

Query: 455 XXXXXXXXXXXYGIELYDHIIDPIESKNLF 484
                      +  ELY    DP +  N++
Sbjct: 478 PENFSADFEDVHAGELYMMETDPNQDNNIY 507


>UniRef50_P22304 Cluster: Iduronate 2-sulfatase precursor (EC
           3.1.6.13) (Alpha-L-iduronate sulfate sulfatase)
           (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa
           chain; Iduronate 2-sulfatase 14 kDa chain]; n=17;
           Tetrapoda|Rep: Iduronate 2-sulfatase precursor (EC
           3.1.6.13) (Alpha-L-iduronate sulfate sulfatase)
           (Idursulfase) [Contains: Iduronate 2-sulfatase 42 kDa
           chain; Iduronate 2-sulfatase 14 kDa chain] - Homo
           sapiens (Human)
          Length = 550

 Score =  436 bits (1074), Expect = e-121
 Identities = 242/516 (46%), Positives = 312/516 (60%), Gaps = 49/516 (9%)

Query: 25  NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+L I++DDLR       DK V  PNI+ L      F NAFAQQA+CAPSR S LTGRRP
Sbjct: 38  NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
           D+ RLYDF SYWR  +   GNF+TIPQ+FKE+GY T SVGKVFHPG SSN TDD PYSWS
Sbjct: 98  DTTRLYDFNSYWRVHA---GNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWS 154

Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK-R 199
             PYHP +E Y++ K CR    + L  NL+CPV V   P  +LPD QS + AI  L+K +
Sbjct: 155 FPPYHPSSEKYENTKTCRGPDGE-LHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMK 213

Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR 259
             + PFFLA+G+HKPHIP ++PKE+ K  P+  +    +P +P  +P V+++PW D+R+R
Sbjct: 214 TSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQR 273

Query: 260 DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTS 315
           +D++ LNI+ P+G +P  +  KIRQSY+A+  Y+D  +G LLS +D       TII  TS
Sbjct: 274 EDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTS 333

Query: 316 DHGWSLGENGLWAKYSNFDYALKVPLIFKSP-----------KLIP--------TVVHEP 356
           DHGW+LGE+G WAKYSNFD A  VPLIF  P           KL P        + + EP
Sbjct: 334 DHGWALGEHGEWAKYSNFDVATHVPLIFYVPGRTASLPEAGEKLFPYLDPFDSASQLMEP 393

Query: 357 -------VELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPF-----IENN-- 402
                  VEL+ +FPTL  L  L    P+C       +LC EGK+L+       +E +  
Sbjct: 394 GRQSMDLVELVSLFPTLAGLAGLQVP-PRCPVPSFHVELCREGKNLLKHFRFRDLEEDPY 452

Query: 403 --SNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXX 460
              N  E  A SQ PRPS  PQ NSDKP LKDI IMGYSIRT  YRYT W+         
Sbjct: 453 LPGNPRELIAYSQYPRPSDIPQWNSDKPSLKDIKIMGYSIRTIDYRYTVWVGFNPDEFLA 512

Query: 461 XXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVL 496
                +  ELY    DP++  N++  S+  ++ ++L
Sbjct: 513 NFSDIHAGELYFVDSDPLQDHNMYNDSQGGDLFQLL 548


>UniRef50_Q08890 Cluster: Iduronate 2-sulfatase precursor; n=22;
           Euteleostomi|Rep: Iduronate 2-sulfatase precursor - Mus
           musculus (Mouse)
          Length = 552

 Score =  431 bits (1061), Expect = e-119
 Identities = 232/509 (45%), Positives = 307/509 (60%), Gaps = 49/509 (9%)

Query: 25  NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+L I++DDLR       DK V  PNI+ L      F NAFAQQA+CAPSR S LTGRRP
Sbjct: 40  NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSVLFQNAFAQQAVCAPSRVSFLTGRRP 99

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
           D+ RLYDF SYWR  S   GNF+TIPQ+FKE+GY T SVGKVFHPG SSN +DDYPYSWS
Sbjct: 100 DTTRLYDFNSYWRVHS---GNFSTIPQYFKENGYVTMSVGKVFHPGISSNHSDDYPYSWS 156

Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK-R 199
             PYHP +E Y++ K C+ +  K L  NL+CPV V   P  +LPD QS + AI  L+K +
Sbjct: 157 FPPYHPSSEKYENTKTCKGQDGK-LHANLLCPVDVADVPEGTLPDKQSTEEAIRLLEKMK 215

Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR 259
             + PFFLA+G+HKPHIP ++PKE+ K  P+  +    +P++P  +P V+++PW D+R+R
Sbjct: 216 TSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPHVPDSLPPVAYNPWMDIRER 275

Query: 260 DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTS 315
           +D++ LNI+ P+G +P  +  KIRQSY+A+  Y+D  +G +LS +D       TII  TS
Sbjct: 276 EDVQALNISVPYGPIPEDFQRKIRQSYFASVSYLDTQVGHVLSALDDLRLAHNTIIAFTS 335

Query: 316 DHGWSLGENGLWAKYSNFDYALKVPLIFKSP-----------KLIP-------------- 350
           DHGW+LGE+G WAKYSNFD A +VPL+   P           KL P              
Sbjct: 336 DHGWALGEHGEWAKYSNFDVATRVPLMLYVPGRTAPLPAAGQKLFPYRDPFDPASDWMDA 395

Query: 351 -TVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENN------- 402
                + VEL+ +FPTL  L  L    P+C       +LC EG++L   ++ +       
Sbjct: 396 GRHTEDLVELVSLFPTLAGLAGLPVP-PRCPIPSFHVELCREGQNLQKHLQLHDLEEEPD 454

Query: 403 --SNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXX 460
              N  E  A SQ PRP+ +PQ NSDKP L DI +MGYSIRT  YRYT W+         
Sbjct: 455 LFGNPRELIAYSQYPRPADFPQWNSDKPSLNDIKVMGYSIRTVDYRYTVWVGFDPSEFLA 514

Query: 461 XXXXXYGIELYDHIIDPIESKNLFLVSKY 489
                +  ELY    DP++  N++  S++
Sbjct: 515 NFSDIHAGELYFVDSDPLQDHNVYNDSQH 543


>UniRef50_UPI0000DB7794 Cluster: PREDICTED: similar to CG12014-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to
           CG12014-PA - Apis mellifera
          Length = 494

 Score =  425 bits (1047), Expect = e-117
 Identities = 228/481 (47%), Positives = 297/481 (61%), Gaps = 39/481 (8%)

Query: 24  KNILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           +N L I++DDLR       D K Y PNI+ L    A F+ AFAQQALCAPSRNS LT RR
Sbjct: 16  QNFLLIIVDDLRTALGCYGDTKAYTPNIDHLATEAAIFSQAFAQQALCAPSRNSFLTSRR 75

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
           PD+L LYDFYSYWR      GNFTT+PQ FK +G+ T S+GKVFHPG SSN +DD PYSW
Sbjct: 76  PDTLHLYDFYSYWR---KDIGNFTTLPQHFKNNGFITKSIGKVFHPGISSNNSDDNPYSW 132

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR 199
           SE P+HP TE YKDA +C+        +NLICPV V   P ++LPD++ L  A  FL  +
Sbjct: 133 SETPFHPFTERYKDAPICQTNMQILPAQNLICPVKVLSMPNKTLPDIEILKEAKYFLSNQ 192

Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEP-NIPKDMPLVSWHPWTDVRK 258
            G+ PFFLA+GF KPHIP K+PK+YL  +      +  +P    K++  ++++PW D+RK
Sbjct: 193 AGN-PFFLAVGFQKPHIPFKYPKKYLSIVQYYHYFKVPQPYKWSKNVSSIAYNPWNDLRK 251

Query: 259 RDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM----QKTIIVLT 314
           R D+  LN+ FP+  +P  +   I QSYYA+  YID+LIG L++ +++    + T I+L 
Sbjct: 252 RKDVAALNLKFPWKKIPKSFAKLIIQSYYASVTYIDDLIGKLINQLEVLSIRKNTTIILM 311

Query: 315 SDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLI---------------PTVVHEPVEL 359
           SDHGWSLGE+  WAKYSN+D AL+VPLI   P L                P  ++  VEL
Sbjct: 312 SDHGWSLGEHTEWAKYSNYDVALRVPLIISIPGLTYKRSKEKANNSLEKNPLFINSIVEL 371

Query: 360 IDIFPTLVDLTKLSDEIPKCLNHKDTSQL-CFEGKSLVPFIE----NNSNGLEAFAISQC 414
           +DIFPT+ DL  +S  IP C N  +T ++ C EG S +P I+      S   +  A  Q 
Sbjct: 372 VDIFPTIADLANIS--IPICSN--ETMEITCSEGISFMPLIQAALRKKSILWKEAAFGQY 427

Query: 415 PRPSVYP--QKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYD 472
           PRPS+ P    NSD+PRLK+I  MGY+IRT +YRYT W+S                ELY+
Sbjct: 428 PRPSIKPSIHPNSDEPRLKEIKAMGYTIRTNKYRYTAWLSFKSETKLPDWNDIIAEELYN 487

Query: 473 H 473
           H
Sbjct: 488 H 488


>UniRef50_A7SLQ8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 514

 Score =  423 bits (1042), Expect = e-117
 Identities = 227/509 (44%), Positives = 310/509 (60%), Gaps = 32/509 (6%)

Query: 16  LTSDVET-PKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPS 70
           LT++ E+ P N+L I+ DDLR        + +  P ++ L      F  + +Q A+CAPS
Sbjct: 7   LTANQESRPPNVLLIIADDLRASLGCYGHRFIQTPYLDSLAVRSVRFTTSASQIAVCAPS 66

Query: 71  RNSLLTGRRPDSLRLYDFYS--YWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKS 128
           R S LT RRPD+LRLY      YWR +    GNFTTIPQ FKE GY T S GKVFHPG+S
Sbjct: 67  RTSFLTSRRPDTLRLYSNKGAFYWRTKV---GNFTTIPQLFKEAGYFTASAGKVFHPGES 123

Query: 129 SNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQS 188
           S  T DYPYSWS   Y PPTE +KD KVCR+     L R+++CPV V  QPG SLPD+Q+
Sbjct: 124 SGETYDYPYSWSVPHYEPPTEKHKDDKVCRHADGS-LHRDIVCPVDVPSQPGGSLPDIQT 182

Query: 189 LDYAIDFLKK-----RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPK 243
             YAI+ L++      + SKPFFLAIGFHKPHIPLKFP++YL+  P+  +    +P++P 
Sbjct: 183 TQYAINLLRQLANQPHDASKPFFLAIGFHKPHIPLKFPRQYLELYPLDSIPSVPDPHLPL 242

Query: 244 DMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSY 303
           D+P V++ PW+D+R+R+DI  LN++FP+  +P  + LKIRQSYYAA  Y+D L+G +L+ 
Sbjct: 243 DLPSVAYEPWSDIREREDISWLNLSFPYEPIPGYYALKIRQSYYAAVSYMDGLVGQVLAA 302

Query: 304 VDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT------VV 353
           +D+    + T+IV   DHGW+LGE+  WAKYSNF     VPLI  +P +  T      V 
Sbjct: 303 LDVNGFKENTVIVFLGDHGWALGEHNEWAKYSNFRVTTNVPLIVHAPGVTMTTSDAGMVS 362

Query: 354 HEPVELIDIFPTLVDLTKLSDEIP-KCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAIS 412
           +  VEL+D+ PTL ++  LS  +P +C +      +C EG S  P ++N S   +    S
Sbjct: 363 NGLVELVDLMPTLAEVCGLS--VPDRCPDDSSKVTVCTEGLSFYPLLKNPSRPWKKAVFS 420

Query: 413 QCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYD 472
           Q PRPS  P  NS +P  KDI+IMGYS++T + RY+EW+                 E Y 
Sbjct: 421 QYPRPSQIPGDNSCQPLPKDISIMGYSLQTAQGRYSEWVRFDPVLSRANWSEVLAREFY- 479

Query: 473 HIIDPIESKNLFLVSKYKNIAKVLSIRLR 501
             + P E  N+  +  Y  + + LS+ LR
Sbjct: 480 --LSPREDINVAAMPLYARLVQELSVLLR 506


>UniRef50_UPI0000E489EA Cluster: PREDICTED: similar to Iduronate
           2-sulfatase precursor (Alpha-L-iduronate sulfate
           sulfatase) (Idursulfase); n=5; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to Iduronate
           2-sulfatase precursor (Alpha-L-iduronate sulfate
           sulfatase) (Idursulfase) - Strongylocentrotus purpuratus
          Length = 567

 Score =  346 bits (850), Expect = 1e-93
 Identities = 167/338 (49%), Positives = 226/338 (66%), Gaps = 20/338 (5%)

Query: 25  NILFILIDDLRHLSDK---KVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPD 81
           N+LFI++DDLR   +     +  PNI+ L    A F +A  QQA+C PSR S LT RRPD
Sbjct: 31  NVLFIVVDDLRPSLNSYGGPILSPNIDNLAAQSAVFQHAMVQQAVCGPSRISFLTSRRPD 90

Query: 82  SLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSE 141
           + +LYDFYSYWR+ +   GN+TT+PQ FKE+GY T SVGKVFH GK+SN TDDYPYSWS 
Sbjct: 91  TTKLYDFYSYWREAA---GNYTTLPQHFKENGYLTASVGKVFHGGKASNGTDDYPYSWSV 147

Query: 142 YPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK--- 198
             +HPPT+ YK AKVC+N     L +N+ICPV+V   P +SLPD+QS D+A+D L++   
Sbjct: 148 EAWHPPTQEYKRAKVCKNMDGT-LHQNIICPVNVTEMPLKSLPDIQSTDHALDLLQQFAS 206

Query: 199 ------RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHP 252
                 ++ S+PFFL +G+HKPH+P K+P+EY    P+ +V     P++P  +P V++ P
Sbjct: 207 SGSQHTKDPSQPFFLGVGYHKPHVPFKYPQEYRALYPLEEVEIAPNPDLPPKLPPVAFEP 266

Query: 253 WTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQK 308
           +T + +RDDI  LNI+FP+G +P  +   +RQSYYAAA Y D  +G LL  ++       
Sbjct: 267 YTSLMERDDIGALNISFPYGPIPRPYHYLLRQSYYAAATYTDFQMGRLLQGLEDNGFANN 326

Query: 309 TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP 346
           TIIV   DHGW LGE+  W K+SNF+ A +VPL+   P
Sbjct: 327 TIIVFVGDHGWQLGEHSEWCKFSNFELATRVPLMVHVP 364



 Score = 87.8 bits (208), Expect = 6e-16
 Identities = 58/157 (36%), Positives = 78/157 (49%), Gaps = 10/157 (6%)

Query: 352 VVHEPVELIDIFPTLVDLTKLSDEIPK-CLNHKDTSQLCFEGKSLVPFIENNSN--GL-- 406
           VV+E VEL+D+FPTL +L  L  ++P  C  +      C EG S  P I   S   G+  
Sbjct: 403 VVNEFVELVDMFPTLAELAGL--QVPSTCPPNPFKVDFCTEGVSFAPLITRGSGRKGVSY 460

Query: 407 ---EAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXX 463
              +    SQ PRP   P   SD P L +ITIMGYS+RT  Y +TEWI            
Sbjct: 461 TRWKNATFSQYPRPGDVPTLESDLPHLVNITIMGYSMRTSDYHFTEWIGFNHSIFQGDWE 520

Query: 464 XXYGIELYDHIIDPIESKNLFLVSKYKNIAKVLSIRL 500
             +  ELY    DP+E  N+     Y+++ + L I+L
Sbjct: 521 DVHARELYVLATDPLEDDNVADSLDYQDLIQDLHIKL 557


>UniRef50_A6CFT9 Cluster: Iduronate-2-sulfatase; n=1; Planctomyces
           maris DSM 8797|Rep: Iduronate-2-sulfatase - Planctomyces
           maris DSM 8797
          Length = 489

 Score =  231 bits (566), Expect = 2e-59
 Identities = 171/477 (35%), Positives = 243/477 (50%), Gaps = 59/477 (12%)

Query: 20  VETPKNILFILIDDLR----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLL 75
           VE P N+LFI  DDLR          V  PN++ L   G  F  A+ QQALC PSR SL+
Sbjct: 30  VEKP-NVLFIGTDDLRCDLACYGHPLVKTPNLDKLATRGVLFKRAYCQQALCNPSRASLM 88

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY 135
           TGRRPD+L ++D  +++R+      N  T+PQ FK+ GY T ++GK+FH  +     D  
Sbjct: 89  TGRRPDTLEIWDLPTHFRE---ADPNIVTLPQLFKQQGYFTQNIGKIFHNWRQKIQGD-- 143

Query: 136 PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLI-CPVSVKRQ-PGQSLPDLQSLDYAI 193
           P SWS  P       + D +   N   ++L  NL   P S  R  P  +  D +  D A+
Sbjct: 144 PASWS-VPAVMHFARHDDDQPMLN-DNRELPVNLAKAPRSESRDVPDSAYFDGRIGDLAV 201

Query: 194 DFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHP 252
             L+  +   +PFFLA+GF KPH+P   PK+Y      S +  P  P  PK++P V+ H 
Sbjct: 202 KALQDLKQKQQPFFLAVGFWKPHLPFNPPKKYWDLYDDSPITVPDNPQPPKNVPDVALHD 261

Query: 253 WTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQK 308
                 R+ +R +      G +     +++R  Y A   Y+D  +G +L+ +D     +K
Sbjct: 262 -----SREILRAVK-----GKLTDAQIIELRTGYLAGISYLDAQLGKVLAELDRLGLREK 311

Query: 309 TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP--KLIPTVVHEPVELIDIFPTL 366
           TIIV  SDHG+ LGE+GLW K SNF+   +VPL+   P  K         VEL+D++PTL
Sbjct: 312 TIIVFWSDHGFHLGEHGLWCKTSNFENDARVPLMISVPHMKTAGKTSDALVELLDMYPTL 371

Query: 367 VDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSD 426
           V+L  L D   K            EG SLVP +++ +  ++  A +Q PRP+ Y ++  +
Sbjct: 372 VELCGL-DSPGK-----------LEGTSLVPVLKDPTQSVKPAAFTQHPRPAYYRKQPEN 419

Query: 427 KPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNL 483
                    MG S+RT RYRYTEW +                ELYDH  DP E+ N+
Sbjct: 420 ---------MGVSVRTPRYRYTEWRNFKTGKVIAR-------ELYDHTSDPEENTNI 460


>UniRef50_A3ZYV7 Cluster: Iduronate-2-sulfatase; n=1;
           Blastopirellula marina DSM 3645|Rep:
           Iduronate-2-sulfatase - Blastopirellula marina DSM 3645
          Length = 469

 Score =  219 bits (536), Expect = 1e-55
 Identities = 163/492 (33%), Positives = 242/492 (49%), Gaps = 55/492 (11%)

Query: 26  ILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPD 81
           +LFI +DDLR       D     P+I+ L +    F  A+ QQALC PSR S++TG  P+
Sbjct: 1   MLFIAVDDLRVQLGCYGDPIAQTPHIDKLAQRSMLFERAYCQQALCNPSRTSVMTGCYPN 60

Query: 82  SLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSE 141
           +L+++D  +++R       +  T+PQFF+ HGY T ++GK++H  + +   D  P SWS 
Sbjct: 61  ALQIWDLPTHFRQL---YPDIVTLPQFFQAHGYFTQNIGKIYHNYRQTLRND--PQSWST 115

Query: 142 YPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNG 201
              H       D  V       K          V       L    + D  +   ++   
Sbjct: 116 PAVHDWGAHSNDWFVSGEPFGLKSISKGPAVQKVDVADEAYLDGRIAADAVLAIRERAAQ 175

Query: 202 SKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPK-DMPLVSWHPWTDVRKRD 260
            +PFFLA+GF KPH+P   PK Y  +    ++ R     +PK D P +++HP+ ++R   
Sbjct: 176 KQPFFLAVGFWKPHLPFNAPKPYWDKYDPDQI-RAHLDQLPKSDAPQIAFHPYGEIRSYT 234

Query: 261 DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQ----KTIIVLTSD 316
           DI +       G +  +  L +   YYAA  ++D  IG +L  +  Q     TI+VL SD
Sbjct: 235 DIPKT------GDISAEQNLVLNHGYYAAISFLDAQIGKVLHELQRQGLAENTIVVLWSD 288

Query: 317 HGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSD 374
           HG+ LGE+ LW K SNF+   +VPL+   P             EL+D++PTLVDL +L  
Sbjct: 289 HGFHLGEHDLWCKTSNFELDTRVPLLIAPPAAANAGQKTTALTELVDLYPTLVDLCEL-- 346

Query: 375 EIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLKDIT 434
            IP  L          +GKSL P + + +  +   A+SQ PRP+ +  KN  KP      
Sbjct: 347 PIPTAL----------QGKSLRPILADPTATVRDAALSQHPRPAYF--KN--KPE----- 387

Query: 435 IMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKN--- 491
           ++GYS+RT R+RY EW                  ELYDH  DP ES+NL     Y++   
Sbjct: 388 VLGYSLRTDRFRYNEWRDFESGQVVAQ-------ELYDHESDPQESRNLASAKAYQSDCA 440

Query: 492 -IAKVLSIRLRS 502
            +AK L+ RL++
Sbjct: 441 TLAKSLAQRLQT 452


>UniRef50_A7AE03 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 478

 Score =  213 bits (521), Expect = 7e-54
 Identities = 155/439 (35%), Positives = 226/439 (51%), Gaps = 49/439 (11%)

Query: 24  KNILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           +N+LFI IDDLR       D     PNI+        F N + QQ++  PSR SLLTG R
Sbjct: 25  RNVLFIAIDDLRPTLGCYGDPYAVTPNIDTFATKSFLFENTYCQQSVSGPSRASLLTGLR 84

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
           PD + + D  +++R++       TT+PQ FK +GY+T  +GK++H    S  T D   SW
Sbjct: 85  PDEIGVTDLNTHFREKCP---YITTLPQLFKNNGYETIGIGKIYH---GSTRTQD-TISW 137

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR 199
           +  P +  +   ++  + +N++  K        + +  QP  S  D +    A+  L K 
Sbjct: 138 TRPPIYNLSIKKEEYTLMQNRQGNKA-----ATIEIADQPDTSFLDGKVTAEALKRLDKL 192

Query: 200 NGSK-PFFLAIGFHKPHIPLKFPKEYLK-QMPISKVHRPKEPNIPKDMPLVSWHPWTDVR 257
           + SK PFFLA+G+ KPH+P   PK+Y       S + +  E   P   P++S+H W ++R
Sbjct: 193 SKSKQPFFLAVGYIKPHLPFSMPKKYWDIYRNKSFIRKEAEDKQPIHAPVISFHNWEELR 252

Query: 258 KRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD---MQK-TIIVL 313
              DI +       G +  +   ++ ++YYA   +ID  +G LL  +    ++K TIIV+
Sbjct: 253 GYTDIPK------HGNLSIEKQEELCKAYYACVSFIDSQVGKLLGKLKELGLEKNTIIVI 306

Query: 314 TSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP--KLIPTVVHEPVELIDIFPTLVDLTK 371
             D+G+ LGE  LW K +NF+   KVPL+  SP  K  P  +++ VELIDI+PTL D   
Sbjct: 307 WGDNGFHLGEQHLWGKSTNFELDCKVPLLIYSPEYKDAPKRINDIVELIDIYPTLTDFCG 366

Query: 372 LSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLK 431
           L          K    L   G+SL   IEN  N     A SQ PRP  Y   NS     K
Sbjct: 367 L----------KPAHTL--SGQSLRFLIENKVNWKNR-AFSQFPRP--YKAVNS----YK 407

Query: 432 DITIMGYSIRTKRYRYTEW 450
           + T MGY++RTK +RYT W
Sbjct: 408 NQTHMGYTVRTKNWRYTLW 426


>UniRef50_Q482E2 Cluster: Sulfatase family protein; n=1; Colwellia
           psychrerythraea 34H|Rep: Sulfatase family protein -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 499

 Score =  204 bits (498), Expect = 4e-51
 Identities = 155/492 (31%), Positives = 238/492 (48%), Gaps = 67/492 (13%)

Query: 25  NILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           NILFI +DDL+ L       KV  PNI+ L      F  A++Q  +C PSR S+LTG RP
Sbjct: 54  NILFIAVDDLKPLIRDYGTAKVQTPNIDKLASQSTVFTRAYSQYPVCGPSRMSILTGLRP 113

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
           +S  + +     RD +    +  T+PQFFK +GY+T + GK+F P  +++ +++   SWS
Sbjct: 114 ESNGIMNLKDKIRDVNP---SVITLPQFFKNNGYETAATGKIFDPRNTTSRSEEEVLSWS 170

Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR- 199
             PY  P    K        KT+    ++        +P +   D   L      LK+  
Sbjct: 171 -IPYQRPKHGLKG-------KTRLAVESI-------DEPDEKFVDGGILKRGKKLLKQMA 215

Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVS-WHPWTDVR- 257
           N +KPFFLA+GF KPH+P   PK+Y               + P+D      +H   ++R 
Sbjct: 216 NKNKPFFLAVGFKKPHLPFVAPKKYYDLYSRESFDLASYQSAPEDADTTYLFHKNQELRG 275

Query: 258 -KRDDIRRLNIT-FPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM----QKTII 311
            K   I+   I  +P G + +    ++   Y+A+  +ID L+G LL  ++     + T+I
Sbjct: 276 YKPTPIKGGEIKPYPKGKLSSAHQKELLHGYFASVSFIDSLVGELLEELEKTGQAENTVI 335

Query: 312 VLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIFPTLVDLTK 371
           V   DHG+ LG++GLW K++  + A  VPLI K P        +PVEL+D+FP+L +   
Sbjct: 336 VFWGDHGFHLGDHGLWGKHTTMEQANHVPLIIKIPGSKANRYAKPVELLDVFPSLTEAAG 395

Query: 372 LSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLK 431
           LS  IP  L          +G SLV  +      ++  AISQ  R   Y           
Sbjct: 396 LS--IPNNL----------QGTSLVSLVTGKLKSIDKVAISQYKRKGAY----------- 432

Query: 432 DITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKN 491
                GYS+RT++YRYT+W++                +LYD I DP+E+KN+    + K 
Sbjct: 433 -----GYSMRTEQYRYTQWVTPSGKVVYR--------DLYDLINDPLETKNIINTPEGKL 479

Query: 492 IAKVLSIRLRSS 503
           +   L+ +L ++
Sbjct: 480 LEVELNKQLHTN 491


>UniRef50_A4A047 Cluster: Iduronate-2-sulfatase; n=1;
           Blastopirellula marina DSM 3645|Rep:
           Iduronate-2-sulfatase - Blastopirellula marina DSM 3645
          Length = 481

 Score =  204 bits (498), Expect = 4e-51
 Identities = 153/491 (31%), Positives = 232/491 (47%), Gaps = 75/491 (15%)

Query: 18  SDVETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNS 73
           S  +   N+LFI +DDLR         +++ PNI+ L   G  F  A+ QQA+C+PSR S
Sbjct: 14  SAADRQPNVLFIAVDDLRTELGCYGASQIHSPNIDRLAAAGTVFTRAYCQQAVCSPSRTS 73

Query: 74  LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTD 133
           L+TG RPDS ++YD  +++R       +  T+ Q FK++GY + S+GK++H G       
Sbjct: 74  LMTGLRPDSTKVYDLVTHFR---KNVPDVVTLGQHFKQNGYYSVSMGKIYHGGY------ 124

Query: 134 DYPYSWSEYPYHPPTE----MYKDAKVCRNKKTKKLERNL--ICPVSVKRQPGQSLPDLQ 187
           D P +WSE    P       + ++ +   +K+     + L  +      R P   + D+ 
Sbjct: 125 DDPPTWSEPARKPQGGAGYVLAENLQTITDKRNAARAKGLRGVQLSRAARGPATEMADVA 184

Query: 188 S--------LDYAIDFLKKRNG-SKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKE 238
                     D A+  L++ +   +PFFLA+GF KPH+P   PK+Y      +K+     
Sbjct: 185 DNAYADGAVADLAVKSLRELSQRDEPFFLAVGFVKPHLPFNAPKKYWDMYDPAKIELAAN 244

Query: 239 PNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIG 298
           P  PK++   S   W ++R  D I +        + P K   +++  YYA   Y D  +G
Sbjct: 245 PYPPKNVTPYSLTSWGEMRVYDGIPKQG-----DLSPEK-ARELKHGYYACISYTDANVG 298

Query: 299 ILLSYVDMQK----TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP--KLIPTV 352
            LL  +D  K    TI+VL  DHGW LGE+  W K++NF+     PLI ++P  K     
Sbjct: 299 KLLDELDKLKLTDETIVVLWGDHGWKLGEHNSWCKHTNFEDDANAPLIIRAPGQKSPGAK 358

Query: 353 VHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAIS 412
               VE +DI+PTL +L  L   +P+ L          EG S  P ++      +  A S
Sbjct: 359 STALVEFVDIYPTLCELAALP--LPQHL----------EGTSAAPLLDQPDAAWKTAAFS 406

Query: 413 QCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYD 472
           Q PR                  IMGY+++T RYR+T W +                ELYD
Sbjct: 407 QYPRRQ----------------IMGYTMKTDRYRFTAWKNKKSGKVVAT-------ELYD 443

Query: 473 HIIDPIESKNL 483
           H +DP E+ N+
Sbjct: 444 HQVDPAENVNV 454


>UniRef50_A6DJJ1 Cluster: Sulfatase family protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Sulfatase family
           protein - Lentisphaera araneosa HTCC2155
          Length = 510

 Score =  200 bits (488), Expect = 7e-50
 Identities = 159/528 (30%), Positives = 251/528 (47%), Gaps = 76/528 (14%)

Query: 2   IYVVNIILLNGDRVLTSDVETPK----NILFILIDDLRHL----SDKKVYLPNINFLGKT 53
           + VV  I+ +   + TS +   K    N+LFI IDDL+ +     D+ +  PNI+ + + 
Sbjct: 5   VLVVMFIITSQVALATSPLAEAKSKKMNVLFIPIDDLKPMLGCYGDQAIITPNIDRIAER 64

Query: 54  GATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHG 113
           G  F NA  QQA+C PSR SL+TG  PD  +++D  +  RD +    +  +IPQ+FK+ G
Sbjct: 65  GTVFLNASCQQAICGPSRASLMTGMYPDHTKVWDLATKMRDINP---DILSIPQYFKQQG 121

Query: 114 YDTYSVGKVFHPG-KSSNFTDDYPYSWSEYPYHPPT-EMYKDAKVCRN-KKTKKLERNLI 170
           Y+T  VGK F P         D P SWS  PYH    + Y + +V +  KK  +L +   
Sbjct: 122 YETTGVGKTFDPRCVDGGKFQDKP-SWS-IPYHKAGGKGYANPEVAKAWKKAAELVKGRT 179

Query: 171 CPVSVKRQPGQS---------------LPDLQSLDYAIDFLKKR------NGSKPFFLAI 209
             +  +R    +               +PD    D A+  +  +         KPFFL++
Sbjct: 180 FKMGYQRNKAMARLGDPICRPATECMDVPDHVYKDGAVARVGAKLLEELSKADKPFFLSV 239

Query: 210 GFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITF 269
           GF KPH+P   PK+Y        +   +     K+   +++    ++    D+       
Sbjct: 240 GFAKPHLPFVAPKKYWDMYNSHDIQVAEYQKSAKNDTKIAYKSLGEIAAYSDMPEK---- 295

Query: 270 PFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENG 325
             G +  +    +   Y A   Y+D  +G+LL  ++       TII L  DHG+ LG++G
Sbjct: 296 --GPIDQETQKHLIHGYMATTSYMDAQLGLLLDKLEELGIANNTIICLWGDHGFHLGDHG 353

Query: 326 LWAKYSNFDYALKVPLIFKSPK-LIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKD 384
           +W K++NF+ A++ PL+  +PK   P   + PVEL+DIFPTL DL  L  +IP  L    
Sbjct: 354 MWTKHTNFEQAVRSPLLIAAPKGFKPNSTNAPVELVDIFPTLCDLAGL--DIPTHL---- 407

Query: 385 TSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKR 444
                  GKSL P +++ S  +   A+ Q      YP+ N           MGY++R++R
Sbjct: 408 ------PGKSLAPVMKDTSTSVRYAALGQ------YPRGNKT---------MGYTLRSER 446

Query: 445 YRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKNI 492
           YRY +W++                +L+D+  DP+E+ NL    +YK I
Sbjct: 447 YRYVKWLN-LDYRKSVAKGKLVATQLFDYEKDPLETVNLAANPEYKKI 493


>UniRef50_Q7UVD4 Cluster: Iduronate-2-sulfatase; n=1; Pirellula
           sp.|Rep: Iduronate-2-sulfatase - Rhodopirellula baltica
          Length = 510

 Score =  195 bits (475), Expect = 3e-48
 Identities = 139/474 (29%), Positives = 221/474 (46%), Gaps = 53/474 (11%)

Query: 25  NILFILIDDLR----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+L I+ DDL        D     PN++ L   G  F+ A+ QQA+C PSR+S LTG RP
Sbjct: 43  NVLLIVADDLNCAIGPYGDPNAITPNLDALANRGLVFDRAYCQQAVCNPSRSSFLTGLRP 102

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
            ++ + D    +R+ +    +  T+PQ FK HGY    +GK+FH     +  D   +S  
Sbjct: 103 TTVGVDDLRKSFRETAPNGASLVTLPQHFKNHGYYCQDIGKIFH--NMGDTQDRQSWSMD 160

Query: 141 EYPY---HPPTEMYKDAKVC-RNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL 196
           E  +   H    ++ +  V  R +K KK        V     P  +  D Q    A   +
Sbjct: 161 EVLHAGTHAADTVHSNTPVALRARKLKKAPATETLDV-----PDTAYRDGQIARLAASVI 215

Query: 197 KK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTD 255
           +   + + PFFL +GF +PH+P   PK+Y       ++  P+    P D+P ++ H   +
Sbjct: 216 RDYPDDAAPFFLGVGFWRPHLPFVAPKKYWDLYDPDEISSPQLETSPVDVPDIAMHISRE 275

Query: 256 VRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM----QKTII 311
           +   D I +     P      +    +R  YYA+  ++D  +G++L+ ++       TI+
Sbjct: 276 LHGYDGIPKEAELSP------ELKRHLRHGYYASISFLDAQVGLILNALEASGHDNDTIV 329

Query: 312 VLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEP--VELIDIFPTLVDL 369
              SDHG+ +GE  LW K SNF+   +VPLI   P++  T        EL+D++PTL  L
Sbjct: 330 AFVSDHGFHIGEKTLWGKTSNFELDARVPLIIADPRVDRTQPRTDCLTELVDLYPTLTSL 389

Query: 370 TKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPR 429
             +++++P+ L          EG  L   + N +  L+  A +Q   P   P++      
Sbjct: 390 AGIANDLPENL----------EGDDLSSLLINPNQTLKTAAFTQHQHPFYAPREK----- 434

Query: 430 LKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNL 483
                 +GYS+RT  +RYT+W S                ELYDH  DP ES+N+
Sbjct: 435 ---WVALGYSVRTADWRYTQWRSIQDHHVIAE-------ELYDHRNDPNESQNV 478


>UniRef50_A6DPD0 Cluster: Sulfatase family protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Sulfatase family
           protein - Lentisphaera araneosa HTCC2155
          Length = 471

 Score =  190 bits (464), Expect = 6e-47
 Identities = 150/495 (30%), Positives = 227/495 (45%), Gaps = 70/495 (14%)

Query: 25  NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+LFI++DDLR       +K+V  PNI+ L   G  F+ A+    +C  SR S++TG RP
Sbjct: 27  NVLFIIVDDLRPELGCYGNKQVLSPNIDRLASEGTLFSKAYCNVPVCGASRASVMTGLRP 86

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
              R   F SY        G    +   F+++GY T S+GKV+H        +DY  SW 
Sbjct: 87  TKDR---FISYNAKAYKESGGVLDLAGIFQKNGYTTISIGKVYHE------RNDYRSSWD 137

Query: 141 --EYPYHPPTEMYKDAKVCRNK--KTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL 196
             + P      M +D  +  N+  + K     L        +P +     Q  D AID++
Sbjct: 138 FKDSPLITSPSM-RDYHLPENQAGRGKYSFEALGTACEAADEPDEKYFTYQLADAAIDYI 196

Query: 197 KK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTD 255
            K    +KP+FLA+GF KPH+P   PK+Y      S       PN+PK+ P  + H W +
Sbjct: 197 DKTEKKNKPWFLAVGFTKPHLPFVAPKKYWDLYKRSDFKLASNPNMPKNAPTQASHQWHE 256

Query: 256 VRKR-DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTI 310
           +RK  +DI +       G +P    L+++  YYA   + D +IG +L Y+D     + T 
Sbjct: 257 LRKMYNDIPQT------GPVPDDKALELKHGYYACVSFTDAMIGRILDYLDTNNLRKNTT 310

Query: 311 IVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP-KLIPTVVHEPVELIDIFPTLVDL 369
           ++L  DHGW LGE+GLW K++NF+ +L  PLI  +  +         VE +DI+P+L DL
Sbjct: 311 VILWGDHGWQLGEHGLWCKHANFETSLNTPLIVSAAGQNAQGPSKALVEFVDIYPSLCDL 370

Query: 370 TKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPR 429
                          T     +GKS  P ++  +   ++   S+      Y   +S    
Sbjct: 371 AGF------------TKPPHLQGKSFAPLLKKPNTKWKSAVFSR------YHAGDS---- 408

Query: 430 LKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKY 489
                     I T R+ YTEW +                 LYDH  DP E+ N+    +Y
Sbjct: 409 ----------IHTNRFLYTEWRNKSNGNITARM-------LYDHQRDPDENFNIAANPEY 451

Query: 490 KNIAKVLSIRLRSSV 504
             + K LS RL++ +
Sbjct: 452 AELVKKLSKRLQAHI 466


>UniRef50_A6DFZ4 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate-2-sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 519

 Score =  190 bits (464), Expect = 6e-47
 Identities = 156/514 (30%), Positives = 246/514 (47%), Gaps = 78/514 (15%)

Query: 25  NILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+L I IDDL+       DK    PNI+ L   G  F + + QQA+CAPSR S+ TG RP
Sbjct: 22  NVLIITIDDLKPTLACYGDKYAVSPNIDSLADNGTLFRSNYCQQAVCAPSRISMFTGLRP 81

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
           D+  + D +++ RD +    N  T+PQ+FKE+GY +   GK+ H  K+    DD   SWS
Sbjct: 82  DTTGILDLHTHMRDIN---PNILTMPQYFKENGYLSIGYGKLMHGAKN----DDKELSWS 134

Query: 141 E----YPYH-----PPTEMYKDAKVCR-----NKKTKKLERNLICPVSVKR-----QPGQ 181
           E     PY+     P  + +++ K  +     NK  K+L+ +L+      +         
Sbjct: 135 ELGDDLPYNKNHPKPVLDKFQNPKAHQVFKKLNKTQKRLKTSLLQKEMKNKGAYLVSEAY 194

Query: 182 SLPDLQSLDYAI--DFLKKRN----GSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHR 235
            LPD    D A+    +++ N      + FF+ +GF+KPH+P   PK+Y      +K+  
Sbjct: 195 DLPDDAYRDGAVAKAGIQRLNELAETKEKFFMVLGFNKPHLPFNAPKKYWDMYDPNKLPL 254

Query: 236 PKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFG-VMPTKWTLKIRQSYYAAALYID 294
            +     +  P  ++H + ++    D       +  G  +  K    +  +YYA   Y+D
Sbjct: 255 AEHQKQDQQRPKYAYHSFGELAAYKD-------YQIGKAVDEKRQRHLIHAYYACVSYVD 307

Query: 295 ELIGIL---LSYVDMQK-TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP-KLI 349
             +G +   L  +++ K TI+VL  DHGW LG++GLW K+SNF+ A + PLI  +P +  
Sbjct: 308 AQVGRVMDELKRLNLDKNTIVVLWGDHGWHLGDHGLWCKHSNFEQATRAPLIISAPNQKK 367

Query: 350 PTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAF 409
             V   P E IDIFP+L  LT L  EIP+ L          EG+ L P +E+    ++ +
Sbjct: 368 GQVSQSPTEFIDIFPSLCKLTGL--EIPEQL----------EGEDLSPILEDPKAKVKDY 415

Query: 410 AISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWI-SXXXXXXXXXXXXXYGI 468
           +ISQ  R + +                GY++R+ +YR T W+                 +
Sbjct: 416 SISQYLRWANH----------------GYTMRSGKYRLTLWMPKNYYGFMKFDENDIVEV 459

Query: 469 ELYDHIIDPIESKNLFLVSKYKNIAKVLSIRLRS 502
           ELYD+  DP E+ N     +Y  + + L  +  S
Sbjct: 460 ELYDYQKDPNETTNFANNPEYAEVLRKLKKQFAS 493


>UniRef50_Q7UZ92 Cluster: Iduronate-2-sulfatase; n=1; Pirellula
           sp.|Rep: Iduronate-2-sulfatase - Rhodopirellula baltica
          Length = 582

 Score =  190 bits (463), Expect = 7e-47
 Identities = 160/505 (31%), Positives = 242/505 (47%), Gaps = 65/505 (12%)

Query: 21  ETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           E   N+LFI +DDLR       D +   PNI+ L      FN A+ Q A+C PSR SL+T
Sbjct: 25  EQRPNVLFIAVDDLRPSIGCYGDPQAITPNIDRLASRSVQFNRAYCQVAVCNPSRASLMT 84

Query: 77  GRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
           G RPD+L ++    ++R+         TIPQ+F+ +GY   S GK++H     N T D P
Sbjct: 85  GLRPDNLAVWTLPIHFRE---AMPEAVTIPQWFRRYGYTAVSHGKIYH-----NPTPD-P 135

Query: 137 YSWSEYPYHPPT--EMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDL---QSLD- 190
            SWSE     P     Y D    + KK      +     +  R P  + P+L   Q LD 
Sbjct: 136 QSWSEPIRDLPRLPAFYPDGTREQMKKFDNELPDRDWRKNNLRGPSTAAPELADDQLLDG 195

Query: 191 ----YAIDFLKKRNGSK-PFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDM 245
                AI+ L++   S  PFFLA+G+ +PH+    PK+Y      SK+       IPK+ 
Sbjct: 196 ARTNMAIEDLRRLGKSDAPFFLAMGYIRPHLAWVAPKKYWDMHDPSKLPVRTGEQIPKNS 255

Query: 246 PLVSWHPWTDVRKRDDIRRLNITFPF--GVMPTKWTLKIRQSYYAAALYIDELIGILLSY 303
           P  + H  +++    D  R+N+  P+    +PT+    +  +YYA   YID  IG LLS 
Sbjct: 256 PPYAMHNNSEMTHYVD--RMNLPKPWDDDTVPTEDARHLMHAYYACVSYIDAQIGRLLSA 313

Query: 304 VDMQ----KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP--KLIPTVVHEPV 357
           +  +     TI+VL SDHGW LGE+  W K +N++    VPL+   P  K +     +  
Sbjct: 314 LKEEGLADNTIVVLWSDHGWKLGEHRGWGKMTNYEIDAHVPLLITGPGVKCLGQQTDQLA 373

Query: 358 ELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRP 417
           EL+D+FPTL ++  +  ++P  +          +G SLVP + +    +   A++Q    
Sbjct: 374 ELLDLFPTLCEMAGI--DVPDFV----------DGSSLVPILNDVDAKVHDGAVNQ---- 417

Query: 418 SVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDP 477
             Y +++  +        MGYSIRT  YR  EW                  ELYDH  D 
Sbjct: 418 --YYRRHEGR------QYMGYSIRTSDYRLVEWRDFFSGEVAAK-------ELYDHRNDD 462

Query: 478 IESKNLFLVSKYKNIAKVLSIRLRS 502
            E++++   ++ K I ++ S+ L +
Sbjct: 463 SENESIVDSTEPKVIDELTSLLLET 487


>UniRef50_Q7UJ67 Cluster: Iduronate-2-sulfatase; n=1; Pirellula
           sp.|Rep: Iduronate-2-sulfatase - Rhodopirellula baltica
          Length = 505

 Score =  190 bits (463), Expect = 7e-47
 Identities = 152/489 (31%), Positives = 230/489 (47%), Gaps = 65/489 (13%)

Query: 25  NILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+LFI +DDL        D     PNI+ L  TG  F  A+ Q  LC P+R S++TG RP
Sbjct: 47  NVLFIAVDDLASALGCYGDVVAKTPNIDRLAATGVCFRRAYNQLPLCNPTRASVMTGLRP 106

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNF-TD--DYPY 137
           D +++YD   ++RD      N  T+ Q F++ GY    VGK++H    ++  TD  D P 
Sbjct: 107 DQIKVYDLDRHFRDE---VPNVITLSQAFQQAGYFAARVGKIYHYNVPASIGTDGFDDPP 163

Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
           SW++   +P      D  +  N +  +     +  ++   +  +    + + + AI  ++
Sbjct: 164 SWNQ-TVNPKGRDKDDEHLIFNAEPHRKISGALSWLAADGEDEEQTDGMIATE-AIRIMR 221

Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEP-NIPKDMPLVSWHPWTDV 256
           ++   +PFFL +GF +PH P   PK+Y    P+  +  P  P    +D+P  ++      
Sbjct: 222 EKK-DEPFFLGVGFFRPHTPYVAPKKYFDMYPLESLRLPFAPAGDREDIPTAAF------ 274

Query: 257 RKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQ----KTIIV 312
                    N   P   +     LK  Q+YYA   +ID  +G LL  ++ Q     TI+V
Sbjct: 275 -------AHNCPVPNYGLDETTLLKATQAYYACVSFIDAQVGRLLDALEEQGLADNTIVV 327

Query: 313 LTSDHGWSLGE-NGLWAKYSNFDYALKVPLIFKSPKLIPT-VVHEPVELIDIFPTLVDLT 370
             SDHG+ LGE NG+W K + F+   K PLI + P  +     +  VE +DI+PTL D+ 
Sbjct: 328 FWSDHGYHLGEHNGVWQKRTLFEEGAKAPLIIRDPSQLGLGSCNRIVEFVDIYPTLTDVA 387

Query: 371 KLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRL 430
            +  E P  L           G+SL P + +        AI+Q  RP+          RL
Sbjct: 388 GI--ESPSGL----------AGRSLKPLLNDPVANWNGTAITQVLRPA--------DDRL 427

Query: 431 KDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYK 490
            +  +MG SIRT RYRYTEW               +G+ELYDH  DP E  NL L    +
Sbjct: 428 PE-QVMGCSIRTHRYRYTEW-----------AEGRHGVELYDHQSDPNEFHNLALDPDER 475

Query: 491 NIAKVLSIR 499
            +A +  +R
Sbjct: 476 AVAVIRRLR 484


>UniRef50_A6DME6 Cluster: Sulfatase family protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Sulfatase family
           protein - Lentisphaera araneosa HTCC2155
          Length = 461

 Score =  188 bits (459), Expect = 2e-46
 Identities = 157/486 (32%), Positives = 220/486 (45%), Gaps = 68/486 (13%)

Query: 25  NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+LFI +DDL+       + +V  PNI+ L    + F NA  Q A+C PSR SL+TG  P
Sbjct: 22  NVLFIAVDDLKPELGAYGNTQVKSPNIDKLASRSSVFTNAHCQWAVCGPSRASLMTGLYP 81

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
           +S  + D  +  R   +   +  T+PQ FK  GY T + GK++ P      T D   SWS
Sbjct: 82  ESTGVMDLKTPMR---SVNPDVLTLPQHFKNSGYFTAATGKIYDPRCVDGRTKDDAPSWS 138

Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK-R 199
             PY   T  Y   K+   K   K                + L D Q L   +D L++ +
Sbjct: 139 T-PY--KTLNYGKVKLKDGKHFAK----------APELNDEDLTDGQILLNGLDLLEQAQ 185

Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR 259
           N  KPFF+A+GF KPH+P   PK+Y       ++  P   +  +      WH   ++R  
Sbjct: 186 NQDKPFFVAVGFKKPHLPFVAPKKYWDLYDRERLTLPSFLDKAQGASDYGWHDSNELRSY 245

Query: 260 DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQ----KTIIVLTS 315
           D I +     P  +   K   +    Y A   YID L+G L+  ++ +     TIIVL  
Sbjct: 246 DGIPKKG---PIAIELQK---EAYHGYLACVSYIDALVGRLIQDLEKRNLADNTIIVLWG 299

Query: 316 DHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIFPTLVDLTKLSDE 375
           DHG+ LG++ +W K++N + A + PLI   PK      H P  LIDIFPTL +   L  E
Sbjct: 300 DHGFHLGDHNMWGKHTNLEQATRSPLIISLPKQKAQKSHTPAGLIDIFPTLCEAAGL--E 357

Query: 376 IPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLKDITI 435
           +P+ +          +G SL P I    +  +  AI      S +  K +          
Sbjct: 358 VPEVV----------QGTSLFPVINGEKDQHKNGAI------SFFKSKGA---------- 391

Query: 436 MGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKV 495
            GYS RTKRYRY EW                 IELYD+  DP E  NL    + K + + 
Sbjct: 392 KGYSYRTKRYRYIEW---------SKGNKVEAIELYDYENDPQEKINLATQQESKELIRT 442

Query: 496 LSIRLR 501
           LS  LR
Sbjct: 443 LSQALR 448


>UniRef50_A6DGT7 Cluster: Sulfatase family protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Sulfatase family
           protein - Lentisphaera araneosa HTCC2155
          Length = 504

 Score =  186 bits (452), Expect = 2e-45
 Identities = 166/528 (31%), Positives = 244/528 (46%), Gaps = 69/528 (13%)

Query: 9   LLNGDRVLTSDVETPKNILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQ 64
           LL G     S  E   NIL I +DDL+ +     D  V  P I+ L +  A +  A+ QQ
Sbjct: 5   LLLGLFTFVSLAEDRPNILIISVDDLKPMLGTYGDPLVQSPTIDKLAEASALYEKAYCQQ 64

Query: 65  ALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH 124
           A+C  SR S++TG RPD+ R+++F    R+R N Q    TIP++FK  GY T   GK+F 
Sbjct: 65  AVCGASRASIMTGLRPDNSRVWEFRQVMRER-NPQA--ITIPEYFKSQGYMTCFAGKIFD 121

Query: 125 PGKSSNFTDDYPYSWSEYPYHPPTEMYKDA----KVCRNK---KTKKLERN--LICPVSV 175
               ++       SWS       +E  K+        R K   K  +L++N       ++
Sbjct: 122 YRCVADGKKQDLKSWSRPEQPRNSEAMKNLGFADPAFREKLRLKEIELKKNGQKASYDAI 181

Query: 176 KRQPGQSLPDLQSLDYAIDF------------LKKRNGSK--PFFLAIGFHKPHIPLKFP 221
           K+  G S     S+D   +             L K  G K  PFF+A+GF KPH+P   P
Sbjct: 182 KKAIGGSPCYEDSIDGPDEIYEDGMIAREGVRLIKELGQKKKPFFIAVGFKKPHLPFNAP 241

Query: 222 KEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLK 281
           K+Y        +++  +  + K    V   P    +   +    N+    G +   +  K
Sbjct: 242 KKYW------DLYKETDFALEKYQKPVQGAPHYAYQNSWEFSGYNVPRINGEVLESFQRK 295

Query: 282 IRQSYYAAALYIDELIGILLSYVDMQ----KTIIVLTSDHGWSLGENGLWAKYSNFDYAL 337
           ++ +Y A   Y+D  I  LL  +  Q     T+IV  SDHG+ LG++G+W K+SN++ A 
Sbjct: 296 LKHAYAACISYVDAQIAKLLKTLKDQGLEKNTVIVFWSDHGFHLGDHGMWCKHSNYEQAT 355

Query: 338 KVPLIFKSPK--LIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSL 395
           +VP     P+  L      +PVELID+FPTL  L+ L+  IP+ L          +GKSL
Sbjct: 356 RVPFFVYDPRQNLKKGRYTQPVELIDMFPTLCQLSGLA--IPEIL----------DGKSL 403

Query: 396 VPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXX 455
           +     N+     FA+SQ PR       N  K +     IMGY  R +RYRY EW+    
Sbjct: 404 LSEAAENAK----FALSQFPR-------NQGKNK----KIMGYGFRFERYRYIEWVDNNY 448

Query: 456 XXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVLSIRLRSS 503
                       +ELYD+  DP+E  NL    +YK+I + L    + S
Sbjct: 449 QQDNTQLGPLKAVELYDYEKDPLEQVNLANNPEYKSILRRLQQEAKES 496


>UniRef50_Q482B9 Cluster: Sulfatase family protein; n=1; Colwellia
           psychrerythraea 34H|Rep: Sulfatase family protein -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 511

 Score =  185 bits (451), Expect = 2e-45
 Identities = 158/507 (31%), Positives = 235/507 (46%), Gaps = 72/507 (14%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGAT 56
           + +VVN +   G   L        N+LFI IDDL +         V  PNI+ L K G  
Sbjct: 21  LAFVVNSV---GAAQLKKSSTLSMNVLFITIDDLNNDLGAYGHHLVKSPNIDALAKKGIR 77

Query: 57  FNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNF---TTIPQFFKEHG 113
           F+ A++Q  +C PSR+S +TG  PD   +    S+ +  ++ + +    TT+PQ FK +G
Sbjct: 78  FDKAYSQSPMCTPSRSSFMTGLYPDQTGIIAHGSHTQMTAHFREHIPKVTTLPQLFKNNG 137

Query: 114 YDTYSVGKVFHPGKSSNFTD---DYPYSWSEYPYHPPTEMYKDAK---VCRNKKTKKLER 167
           Y +  VGK++H G  +       D   SW E     P  + KD +   +  N+K    + 
Sbjct: 138 YFSGRVGKIYHQGVPNQIGTSGADDAASWHETVN--PIGLDKDVEDKIIAFNEKALVRQS 195

Query: 168 -NLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSK---PFFLAIGFHKPHIPLKFPKE 223
              +          ++  D +     I+ +K  +  K   PFF+  GF++PH P   PK+
Sbjct: 196 FGGVLSFLAIGDDDKAHTDGKVATETINMIKDHHPDKTGKPFFIGAGFYRPHTPFVAPKK 255

Query: 224 YLKQMPISKVHRPKEP-NIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKI 282
           Y    P+ K+     P N  KD+P        D+  +D   ++ +T            +I
Sbjct: 256 YFDLYPLEKIKPYIAPKNDRKDIP--------DIALQDREGQVGLTL-------NQRKQI 300

Query: 283 RQSYYAAALYIDELIGILLSYVDMQ----KTIIVLTSDHGWSLGENGLWAKYSNFDYALK 338
            Q YYAA  Y+D  +G +L  +  Q     TI+V  SDHG+ LG++GLW K S F+ + +
Sbjct: 301 IQGYYAAVSYVDAQVGRVLDALKQQDLSDNTIVVFLSDHGYELGQHGLWQKGSLFEGSAR 360

Query: 339 VPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLV 396
            PLI  +P +     VV  PVEL+DI+PTL  LT L    P+ L           GK L 
Sbjct: 361 APLIIYAPNVKDNGRVVTSPVELVDIYPTLAKLTGL--VAPEYL----------AGKDLT 408

Query: 397 PFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXX 456
           P +    N ++ F + +    ++  +   D  +     I G+SIRT RYRYTEW      
Sbjct: 409 PAL----NDVD-FQVRKGAYSAILNRNKGDNNQFAFTKIRGHSIRTNRYRYTEW------ 457

Query: 457 XXXXXXXXXYGIELYDHIIDPIESKNL 483
                    +G ELYDH  DP E KNL
Sbjct: 458 -----GEGYFGAELYDHKNDPQELKNL 479


>UniRef50_Q482C5 Cluster: Sulfatase family protein; n=1; Colwellia
           psychrerythraea 34H|Rep: Sulfatase family protein -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 502

 Score =  182 bits (444), Expect = 2e-44
 Identities = 160/507 (31%), Positives = 227/507 (44%), Gaps = 80/507 (15%)

Query: 25  NILFILIDDLR----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+LFI +DDLR         K   PNI+ L   G  F  A++   +C  SR S+LTG RP
Sbjct: 44  NVLFIAVDDLRVQYGPYDFDKAITPNIDRLVNQGVAFTQAYSNVPVCGASRASMLTGVRP 103

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
              R   F S   D+        +I + F ++GY TYS+GK+F     +N T D+   WS
Sbjct: 104 TINRFVAFES--ADKVAPWA--PSIAKVFSDNGYTTYSLGKIF-----NNLT-DHANDWS 153

Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERN--------LICPVSVKRQPGQSLPDLQSLDY- 191
           E+P+ P     +D+     K+   L R+         +    +K  P     D+    Y 
Sbjct: 154 EFPWRPEGAKNEDSTSGNKKQASLLSRHDYVTSDGVAMAKKGIKNHPAFEKADVVDDAYK 213

Query: 192 -------AIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPK 243
                  AI  LK+ +   KPFFLA+G  KPH+P   P +Y      S +   K P   K
Sbjct: 214 NGKIAKRAISDLKRLKKAGKPFFLAVGLKKPHLPFNAPSKYWDLYDESTIELTKIPLKAK 273

Query: 244 DMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSY 303
           D P  S H W ++R       +      G M  +   K+   Y+AA  Y D LIG +L+ 
Sbjct: 274 DSPSQSDHNWNELRNYGHDGAMP---KKGKMSDEMARKLIHGYHAATSYSDALIGNILTE 330

Query: 304 VDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEP-VE 358
           ++     + TI+VL  DHGWSLGE+  WAK+S++D    +PLI K P +      +  VE
Sbjct: 331 LESLGLEENTIVVLWGDHGWSLGEHTHWAKHSSYDVTNHIPLIIKVPGMTNGEFSKGLVE 390

Query: 359 LIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPS 418
            +DIFPTL  L  L    P  L          +G SLVP ++N    +           +
Sbjct: 391 SVDIFPTLTQLAGL--PAPSSL----------QGDSLVPMLKNPQATV---------NDA 429

Query: 419 VYPQ-KNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDP 477
           VYP+ KN+D            SIRT  Y YTEW +                 L+DH +DP
Sbjct: 430 VYPRWKNAD------------SIRTPNYMYTEWRNKKNNKVIARM-------LFDHRVDP 470

Query: 478 IESKNLFLVSKYKNIAKVLSIRLRSSV 504
            E+ N+    KY  +   L  +L + +
Sbjct: 471 RETINVAENFKYAQVVVDLHNQLAAHI 497


>UniRef50_A6DPE5 Cluster: Iduronate-2-sulfatase; n=2; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate-2-sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 487

 Score =  175 bits (427), Expect = 2e-42
 Identities = 158/500 (31%), Positives = 235/500 (47%), Gaps = 67/500 (13%)

Query: 25  NILFILIDDLR----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+LFI  DDL        + +V  PN++ L + G  F+ A+ QQ LC PSR S+++G RP
Sbjct: 22  NVLFISADDLNCDIGPYGNTQVKTPNLDRLARMGTVFDRAYCQQPLCGPSRASIMSGLRP 81

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGK----SSNFTDDYP 136
           ++L ++   S  R R     N  T+ +FF++ GY +  VGK++H G      +N  DD  
Sbjct: 82  NTLGVWTLNSKLRGRIP---NLVTMGEFFQKQGYYSGRVGKIYHYGNPTYIGTNGNDD-E 137

Query: 137 YSWSEYPYHPPTEMYKDAKVCR---NKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAI 193
            +W+E       +  ++  + R    K  KK    +               D    D AI
Sbjct: 138 QTWTERFNPKGIDRTQEENIIRYPGGKTGKKGGLGISMAWWDPVSKDNEHTDGLVADRAI 197

Query: 194 DFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPW 253
             ++  N  KPFF+A GF  PH P   PK+Y     I+ +   +     +++  V   P 
Sbjct: 198 KMIEA-NKDKPFFIAAGFFNPHCPYVAPKKYFDMYDINDIELQELEEAKQELADV---PA 253

Query: 254 TDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKT 309
             ++ RD  +R    +  G+   +   + + +YYA   +ID  +G +   ++    M KT
Sbjct: 254 MAIQ-RDAGQRWPYFYK-GLTRDE-AKQCKLAYYATVSFIDAQVGRIFEALEKNNLMDKT 310

Query: 310 IIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP-TVVHEPVELIDIFPTLVD 368
           IIV  SDHG+ LGE GLW K   F+ + + PL+  +P L    V   PVEL+DI+PTLV+
Sbjct: 311 IIVFWSDHGYFLGEKGLWFKRKAFERSARAPLLIAAPGLSKGQVCKSPVELLDIYPTLVE 370

Query: 369 LTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKP 428
            T    +IP        S+L  EG SL P ++N        AI+Q           +DK 
Sbjct: 371 ATGF--QIP--------SEL--EGVSLSPLLKNAQTKWTKPAITQI-------HHGADK- 410

Query: 429 RLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLVSK 488
                   GYSIRTK++RYTEW                G ELY+H  DP E+ NL    +
Sbjct: 411 -------QGYSIRTKKWRYTEWNKGQA-----------GKELYNHETDPEETINLATNPE 452

Query: 489 YKNIAKVLSIRLR--SSVYV 506
           +  I   LS  L+  SS Y+
Sbjct: 453 HTQIVAQLSTELQKFSSSYI 472


>UniRef50_Q7UWE8 Cluster: Iduronate-2-sulfatase; n=1; Pirellula
           sp.|Rep: Iduronate-2-sulfatase - Rhodopirellula baltica
          Length = 488

 Score =  173 bits (421), Expect = 9e-42
 Identities = 130/441 (29%), Positives = 217/441 (49%), Gaps = 45/441 (10%)

Query: 23  PKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           P N+L I +DDLR          ++ PNI+ L  +G  F+ A+ Q A+C  SR SL++G 
Sbjct: 34  PLNVLMIAVDDLRPELGCYGKSYMHSPNIDRLAASGMRFDRAYCQVAVCGASRASLMSGC 93

Query: 79  RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGK--SSNFTDDYP 136
           RP++ + ++F +  R +     +  T+PQ    +GY+T  +GKV+H     ++ +T D  
Sbjct: 94  RPETTQCWNFKTLLRSQ---MPDVLTLPQHLSRNGYETGFLGKVYHSASDDAAAWTVD-A 149

Query: 137 YSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL 196
             W+           ++    RN      E+N     +    P  +  D  + D A+  L
Sbjct: 150 NEWAPRDRSKGKSYVQELPRKRNPANSS-EKNGPSIENGGDVPDSAYTDGHNADRAVALL 208

Query: 197 KK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTD 255
           ++     KPFFLA+GF KPH+P   P +Y        +  P   ++   +P      W +
Sbjct: 209 ERFSTQDKPFFLAVGFLKPHLPFNAPAKYWDLYDRDDIKIPSREDVVDGLPYAR-SSWGE 267

Query: 256 VRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM----QKTII 311
           ++   DI          ++  + T ++   Y AA  Y+D  +G +L+ ++     + TI+
Sbjct: 268 LKNYTDIPAKT-----DMLDDEKTRELIHGYRAAVSYMDAQVGKVLNALEANGQRENTIV 322

Query: 312 VLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIFPTLVDLTK 371
           VL  DHGW +G+ G W K++N++ A +VPLI  +P +        VEL+D+FPTL +LT+
Sbjct: 323 VLWGDHGWYVGDFGDWCKHTNYEIATRVPLIVSAPGVPAGETKSLVELVDLFPTLCELTE 382

Query: 372 LSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLK 431
           L   +P+   H      C +GKS+   +  +  GL         RP+ + Q    K +L 
Sbjct: 383 L--PVPE---H------C-QGKSIAGVV--HDPGLSV-------RPAAFSQYK--KSKLG 419

Query: 432 DITIMGYSIRTKRYRYTEWIS 452
              ++G SIRT R+RYTE++S
Sbjct: 420 VGPVLGTSIRTDRFRYTEYVS 440


>UniRef50_A6CG48 Cluster: Sulfatase family protein; n=1;
           Planctomyces maris DSM 8797|Rep: Sulfatase family
           protein - Planctomyces maris DSM 8797
          Length = 472

 Score =  169 bits (411), Expect = 1e-40
 Identities = 120/369 (32%), Positives = 178/369 (48%), Gaps = 29/369 (7%)

Query: 17  TSDVETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRN 72
           T   E P N+LFI +DDLR        + ++ PNI+ L ++   F  AF     C  SR 
Sbjct: 17  TFAAERP-NVLFIAVDDLRPELACYGKQHIHSPNIDKLAESSVLFERAFCMVPTCGASRA 75

Query: 73  SLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFT 132
           SL+TG RP   R  +F + W +R     N TT+   FK++GY T S+GK+FH        
Sbjct: 76  SLMTGIRPARNRFVNFLA-WAERD--APNATTMNTQFKQNGYYTASLGKIFH------HP 126

Query: 133 DDYPYSWSEYPYHPPTEMYKDAKVCRNKKT--KKLERNLICPVSVKRQ-PGQSLPDLQSL 189
            D    WSE P+ P    +      + K    +KL      P       P  +  D    
Sbjct: 127 ADNRQGWSEPPWRPKGVQWYQRPENQEKHAARQKLGNKKKGPAWESADVPDNAYMDGVLA 186

Query: 190 DYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLV 248
           + AI+ L++     +PFFLA+GF KPH+P   P++Y       K+  P    +P+D P  
Sbjct: 187 EKAIEKLQQLEKQEQPFFLAVGFFKPHLPFIAPQKYWDLYDHDKIQLPANHKVPQDAPKE 246

Query: 249 SWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD--- 305
           S H + ++R   DI         G +  +    +   YYA   Y D  IG LL+ +D   
Sbjct: 247 SIHRFGELRAYADIPAK------GPVSEETARNLIHGYYACVSYTDAQIGKLLAELDRLQ 300

Query: 306 -MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEP-VELIDIF 363
               TI+VL  DHGW+LG++ LW K+S ++ +L +PLI ++P +         +E ID++
Sbjct: 301 LSDNTIVVLWGDHGWNLGDHTLWCKHSCYESSLHIPLIVRAPGIKGGERRSSLMESIDVY 360

Query: 364 PTLVDLTKL 372
           PTL DL  +
Sbjct: 361 PTLCDLADI 369


>UniRef50_Q7UW58 Cluster: Iduronate-2-sulfatase; n=1; Pirellula
           sp.|Rep: Iduronate-2-sulfatase - Rhodopirellula baltica
          Length = 541

 Score =  166 bits (404), Expect = 1e-39
 Identities = 150/477 (31%), Positives = 216/477 (45%), Gaps = 71/477 (14%)

Query: 24  KNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           KN+LF++ DDL        D  V  PNI+ L   G  F NA  Q  LC PSRNS+L G  
Sbjct: 67  KNVLFLISDDLNTRIGCYGDPIVQTPNIDRLAARGVLFENAACQYPLCGPSRNSMLCGLY 126

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH---PGKSSNFTDDYP 136
           PD+  ++     +RD    + +   +PQ F+  GY    VGK++H   P        D P
Sbjct: 127 PDTTGIHGNAQIFRDSIPERWS---LPQAFRLDGYFAGRVGKLYHYNVPKSVGTNGHDDP 183

Query: 137 YSWSEYPYHPP--TEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLD---Y 191
            SW E   +P     + ++  +   +K       L    S +  P ++  D    D   +
Sbjct: 184 ASW-ELELNPAGCDRLIEEPDIFTLRKGA-FGGTLSWYASPR--PDEAHTDGMLADDASW 239

Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWH 251
            ++   KRN  +PFFLA+GF++PH P   PKEY +  P      P   N+ +D   V   
Sbjct: 240 VLERCAKRN-DRPFFLAVGFYRPHTPYVAPKEYFE--PYKLEDMPLFDNVEEDNADVPAA 296

Query: 252 PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM----Q 307
                +K  D+  LN          +   +  Q+YYA+  ++D  +G +L  +      +
Sbjct: 297 ALLSKKKEQDL--LN---------DELRRQAIQAYYASTTFMDAQVGKVLDTLKRTGLDK 345

Query: 308 KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP-KLIPTVVHEPVELIDIFPTL 366
            TI+V TSDHG+ LGE GLW K + FD    VPLI   P +    +   PV L+D++PTL
Sbjct: 346 NTIVVFTSDHGYFLGEKGLWQKQALFDKVAGVPLIIAEPGRTEGAIAKSPVGLVDLYPTL 405

Query: 367 VDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSD 426
            +L     ++P        +Q   +G+SLVP + + S     +++S   R          
Sbjct: 406 AELC----DVP--------TQKLMQGQSLVPMLRDPSQTGRGYSMSMVAR-----NDRQT 448

Query: 427 KPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNL 483
           K R       GYSIRT+RYR T W                G ELYDH  DP E  NL
Sbjct: 449 KQR-----YYGYSIRTERYRLTLW-----------DDGKRGTELYDHQNDPEEFTNL 489


>UniRef50_UPI0000E0F7B6 Cluster: iduronate 2-sulfatase precursor;
           n=1; alpha proteobacterium HTCC2255|Rep: iduronate
           2-sulfatase precursor - alpha proteobacterium HTCC2255
          Length = 499

 Score =  165 bits (400), Expect = 3e-39
 Identities = 112/372 (30%), Positives = 184/372 (49%), Gaps = 33/372 (8%)

Query: 17  TSDVETPKNILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRN 72
           T +    +NI+ I++DDLR +     DK  Y PNI+ L   G TF  A+A   +C  SR 
Sbjct: 48  TLEQSPQQNIVMIIVDDLRPVLGVYGDKNAYSPNIDALAAQGITFTQAYANVPVCGASRA 107

Query: 73  SLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFT 132
           S+LTG RP+  R  D+ +  +  + G     ++PQ  +E GY T  +GK+FH     N  
Sbjct: 108 SMLTGIRPNKTRFIDYKAKAQKDAPGA---KSLPQVLRESGYHTMGIGKIFH-----NSK 159

Query: 133 DDYPYSWSEYPYHP----PTEMYKDAKVCRNKKTKKLERNLICP-VSVKRQPGQSLPDLQ 187
           D    SWSE   +      T +  D++     KT K  +    P         ++ PD +
Sbjct: 160 DLAKVSWSEKLQNAGMGHATRLNPDSE--NYLKTTKFNKRGNGPWYETMDVADEAYPDGK 217

Query: 188 SLDYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMP 246
             + A+  L +     +PFFL++GF +PH+P   PK+Y    P  K     + N P++ P
Sbjct: 218 VKEKALKALTRLAKQEQPFFLSVGFIRPHLPFYAPKKYYDLHPREKFSPFFDRNKPRNAP 277

Query: 247 LVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD- 305
                    +    +I   +    +      + +   Q YYA+  YID L+G +++ +D 
Sbjct: 278 -------KSLNGSGEIHTYHFK-DYTYNSDAFHMSSLQGYYASVSYIDALVGDVIAQIDS 329

Query: 306 ---MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEP-VELID 361
                 T I+LTSDHG++LGE+  W K++  + +L++P+I   P +      +  VEL+D
Sbjct: 330 LGLRDNTTIMLTSDHGFNLGEHNFWTKHTMLETSLRIPMIVAGPNIAKDEKTDALVELVD 389

Query: 362 IFPTLVDLTKLS 373
           +FPT+ ++TK++
Sbjct: 390 VFPTITEITKVN 401


>UniRef50_Q7URV9 Cluster: Iduronate-2-sulfatase; n=2; Bacteria|Rep:
           Iduronate-2-sulfatase - Rhodopirellula baltica
          Length = 573

 Score =  164 bits (399), Expect = 4e-39
 Identities = 144/506 (28%), Positives = 228/506 (45%), Gaps = 66/506 (13%)

Query: 25  NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+LFI +DDLR             P+++ L   G  FN A+ QQA+C PSR SL+TG RP
Sbjct: 64  NVLFIAVDDLRPELGCYESPIAKTPHLDQLAADGLLFNRAYCQQAICRPSRASLMTGARP 123

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
           D+  LY  Y   R+    Q N  T+P+ F  +GYD    GK+FH G     TDD   SW+
Sbjct: 124 DTTGLYHNYVSLREL---QPNILTLPEHFVANGYDAAYCGKIFHQGD----TDD-GRSWN 175

Query: 141 EYPY------HPPTEMY---KDAKV-CRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLD 190
                       P   Y   ++ K+   N K+   +        +   P     D+   D
Sbjct: 176 RESVKRLDGIRKPKGGYALPENLKMKSDNMKSMLAKYGEAARRGLAAGPAYEKADVADTD 235

Query: 191 Y--------AIDFLKK--RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPN 240
           Y        AI  LK+  ++   PFFLA+G+  PH+    P +Y      + +    E +
Sbjct: 236 YVDGYNTAMAIATLKEMTQDNETPFFLAMGYKLPHLNWCAPSKYWDLYDANDIPMAVETD 295

Query: 241 IPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGIL 300
            P++   +  H   ++R R  I ++      G +  + + K++ +Y A+  Y+D  IG L
Sbjct: 296 APENGAAMGLHASFELRTRAGIPKI------GPLSPELSRKLKHAYLASVSYVDAQIGKL 349

Query: 301 LSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP--KLIPTVVH 354
           ++ ++       T+IV+  DHGW LG+ G+W K +N++ A +VPL+  +P  K       
Sbjct: 350 IAALEDAGVRDNTVIVVWGDHGWHLGDMGVWGKATNYEIATRVPLMIWAPDMKARGATTD 409

Query: 355 EPVELIDIFPTLVDLTKLS-------DEIPKCLNH-----KDTSQLCFEGKSLVPFIENN 402
             VEL+DI+PTL +L +++             +N+     K  +   +   +L  +  N 
Sbjct: 410 ALVELVDIYPTLCELAEINVPEHTEGTSFKPLMNNPNQPWKKAAFSQYPNPALREWAANP 469

Query: 403 -SNGLEAF----AISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXX 457
            S G+        I Q     +  Q  +    L +  +MGY++RT RYR   W       
Sbjct: 470 LSQGMRETWFGPLIEQVEERIINQQGKAWDRELFEQHLMGYTMRTDRYRLVIWKDHRDPS 529

Query: 458 XXXXXXXXYGIELYDHIIDPIESKNL 483
                     +EL+DH  DP E+KN+
Sbjct: 530 ASPIY-----VELFDHANDPNETKNI 550


>UniRef50_A6C9F6 Cluster: Iduronate-2-sulfatase; n=1; Planctomyces
           maris DSM 8797|Rep: Iduronate-2-sulfatase - Planctomyces
           maris DSM 8797
          Length = 506

 Score =  162 bits (394), Expect = 2e-38
 Identities = 122/387 (31%), Positives = 185/387 (47%), Gaps = 35/387 (9%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGAT 56
           +I  +   L+    V ++D  T  N+LF++ DDL          +V  PNI+ L K G  
Sbjct: 25  IITCIFCFLITTQSVFSAD--TKPNVLFLICDDLNCDLGCYGHPQVQSPNIDQLAKQGVR 82

Query: 57  FNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDT 116
           F +A+ Q  LC PSR S +TG  PD   ++    Y R+      N  T+ Q F++HGY  
Sbjct: 83  FEHAYCQFPLCGPSRASFMTGMYPDQTLVHRNGIYIREHVP---NVKTMSQMFRDHGYFA 139

Query: 117 YSVGKVFH---PGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPV 173
             VGK++H   P        D PYSW++  ++P      D     +         L    
Sbjct: 140 TRVGKIYHYNVPKHIGTSGHDDPYSWNQ-TFNPRGRDVDDEDQIFSLVPGSYGGTLSWLA 198

Query: 174 SVKRQPGQSLPDLQSLDYAIDFLKKRNGSK-PFFLAIGFHKPHIPLKFPKEYLKQMPISK 232
           +      Q+  D  + D AI  LKK   SK PFFLA+G ++PH P   PK Y ++ P+ +
Sbjct: 199 AEGTDAEQT--DGIAADIAIQQLKKFAESKEPFFLAVGLYRPHTPYVAPKSYFEKYPVEQ 256

Query: 233 VHRPKEPN-IPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAAL 291
           +  P+ P+   K +P  +    T  RK+D I           +P K   +  Q+YYA+  
Sbjct: 257 IKVPQIPDGYLKTIPASARKSVT--RKKDQID----------LPDKLARQAIQAYYASIT 304

Query: 292 YIDELIGILLSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPK 347
           + D  +G +LS +      + TI+V TSDHG+ +GE+G W K + F+ A  VP+I   P 
Sbjct: 305 FADAQLGHILSALKETGLDENTIVVFTSDHGYHMGEHGHWQKTTLFENATHVPMIIAGPG 364

Query: 348 LIP--TVVHEPVELIDIFPTLVDLTKL 372
           +         P E++D +PTL +L  L
Sbjct: 365 VTAKGQAAAAPAEMVDFYPTLAELCGL 391



 Score = 40.7 bits (91), Expect = 0.089
 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 12/72 (16%)

Query: 428 PRLKDIT--IMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFL 485
           PR   +T  + GYS+RT  +RYTEW                G+ELYDH  DP E  NL  
Sbjct: 413 PRKTALTQYLNGYSLRTPTFRYTEW----------GTNGSEGVELYDHSSDPAEMHNLAN 462

Query: 486 VSKYKNIAKVLS 497
            +K + +   L+
Sbjct: 463 QAKTQKLRDELA 474


>UniRef50_A4AWR8 Cluster: Iduronate-2-sulfatase; n=5; Bacteria|Rep:
           Iduronate-2-sulfatase - Flavobacteriales bacterium
           HTCC2170
          Length = 498

 Score =  161 bits (392), Expect = 3e-38
 Identities = 124/392 (31%), Positives = 191/392 (48%), Gaps = 42/392 (10%)

Query: 7   IILLNGDRVLTSDVETPKNILFILIDDLRHLS-----DKKVYLPNINFLGKTGATFNNAF 61
           ++LL      + + + P N+LFI+ DDL   +     + +V  P+I+ L   G  F   +
Sbjct: 25  LVLLFALSSCSQEAKKP-NVLFIIADDLTTTAVSSYGNSEVNTPHIDKLASEGVLFTRTY 83

Query: 62  AQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK 121
           +Q  +C PSR S ++G  P +   Y + S    R N      T  Q FK++GY T  V K
Sbjct: 84  SQYPVCGPSRASFMSGYYPSATTTYGYVS---GRKNIGSERKTWSQVFKDNGYYTARVSK 140

Query: 122 VFHPG------KSSNFTDDYPYSWSEY--PYHPPTEMYKDAKVCRNKKTKKLERNLICPV 173
           +FH G      K SN  DD   SW+E      P  +     ++ +      L       +
Sbjct: 141 IFHMGVPIDIEKGSNGQDD-EQSWTERFNSQGPEWKAPGAGELVQGNPDGTLPIKGGNVM 199

Query: 174 SVKRQPGQSL--PDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPIS 231
           ++ +  G  L   D ++ + A + ++K    KPFFLAIGF +PH+P   PK Y +  P +
Sbjct: 200 TIVKADGDDLVHSDGKTAEKASELIRKHK-DKPFFLAIGFVRPHVPFVAPKSYFEPYPHN 258

Query: 232 KVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLN-ITFPFGVMPTKWTLKIRQSYYAAA 290
           +   PK+  +  D        W D+ KR     +N +T   G M T+   K   +YYA+ 
Sbjct: 259 QTKLPKK--VEND--------WDDIPKRG----INYVTSVNGKMNTEQEKKAIAAYYASV 304

Query: 291 LYIDELIGILLSYVDMQ----KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP 346
            Y+D  +G +L  +  +     TI+V TSDHG+ LGE+  W K S  + ++KVPLI K P
Sbjct: 305 SYMDAQVGKVLKTLKEEGLEDNTIVVFTSDHGFHLGEHEFWMKVSLHEESVKVPLIIKVP 364

Query: 347 KLIPTVVHEPVELIDIFPTLVDLT--KLSDEI 376
              P V H   EL+D++PT+  L   K SD++
Sbjct: 365 GKKPAVCHSFTELLDLYPTITALAGLKYSDQL 396


>UniRef50_A6DJM0 Cluster: Sulfatase family protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Sulfatase family
           protein - Lentisphaera araneosa HTCC2155
          Length = 713

 Score =  161 bits (391), Expect = 4e-38
 Identities = 138/507 (27%), Positives = 226/507 (44%), Gaps = 59/507 (11%)

Query: 19  DVETPKNILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSL 74
           + +T KNILFI +DDL+ +     D  V  PNI+ L   G  F N  +Q A+C PSR SL
Sbjct: 22  NAQTKKNILFIAVDDLKPILACYGDSTVLTPNIDRLAAQGTVFMNNHSQFAVCGPSRASL 81

Query: 75  LTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHP--------- 125
           +TG  P+   +  F     +++    +  T+PQ FK +GY+T + GK+            
Sbjct: 82  MTGLMPEETGVTSFIKMRSNKNAQLKDLITLPQHFKNNGYETAATGKLNDNRCVGSVNAD 141

Query: 126 ---GKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQS 182
                  N  DD P SWS  PY      ++     +   +  + +     +        +
Sbjct: 142 GTVNDDGNDVDD-PASWS-IPYVKAGPGHQGPTAIKQGTSNTVMKKATESID---DVDSA 196

Query: 183 LPDLQSLDYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPN- 240
            PD + L+ A+  L       K FFL +GF KPH+P   PK+Y                 
Sbjct: 197 FPDGKVLEEALVLLNDLATNDKSFFLGVGFKKPHLPFVAPKKYWDLYNRDDFSPANHQGA 256

Query: 241 IPKDMPLVSWHPWTDVRKR----DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDEL 296
           I  D   V  +   ++R +     D   L I         +   ++   YYA   ++D L
Sbjct: 257 ILNDSGYV-MNSVEELRNKYYFQTDASGLAIPLTSETFSHEEQKELIHGYYACVSHVDAL 315

Query: 297 IGILLSYVDMQK----TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLI-PT 351
           IG+LL  ++  K    TIIVL  DHG+ LG++  W K++  + + + PLI  +P      
Sbjct: 316 IGVLLDELENLKLSDNTIIVLWGDHGFHLGDHNRWGKHTVLEQSTRSPLIISAPAYPGGQ 375

Query: 352 VVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAI 411
               P   +D++PTL  +  L+ +  + LN    +     GKSL+P + + +  ++  A+
Sbjct: 376 TTQSPTTFLDLYPTLCAMNGLA-QPQQPLNSTQVTGRPLRGKSLIPILNDPTALVQIGAV 434

Query: 412 SQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELY 471
           S     ++YP+  +          +GY+ RT+ YRY EWI                 +LY
Sbjct: 435 S-----TIYPKNGA----------IGYAYRTEDYRYIEWIKDGEVVAQ---------DLY 470

Query: 472 DHIIDPIESKNLFLVSKYKNIAKVLSI 498
           D++ DP E++N+   + Y+ +A+ + I
Sbjct: 471 DYLHDPDETQNIAQDNSYE-LAQTMHI 496


>UniRef50_UPI0000E11054 Cluster: iduronate-2-sulfatase; n=1; alpha
           proteobacterium HTCC2255|Rep: iduronate-2-sulfatase -
           alpha proteobacterium HTCC2255
          Length = 1028

 Score =  156 bits (379), Expect = 1e-36
 Identities = 116/367 (31%), Positives = 176/367 (47%), Gaps = 39/367 (10%)

Query: 19  DVETPKNILFILIDDLR----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSL 74
           D  +  NIL  +IDDLR             PNI+ L   G +FN A+AQQA+C PSR S+
Sbjct: 41  DKNSKPNILVFMIDDLRPDLGSYGHAHAITPNIDKLANQGVSFNRAYAQQAICGPSRVSI 100

Query: 75  LTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDD 134
           +TG RP++  LY      R R N Q N  ++PQ FK +GY T S+GKV+H     + TDD
Sbjct: 101 MTGLRPETTGLYTIRRDGRLRPN-QPNVVSLPQLFKANGYKTISIGKVYH-----STTDD 154

Query: 135 YPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAID 194
              +WS +    P   Y D +       K+  R      +V+    +     +  D A+ 
Sbjct: 155 QE-NWSTHIKKLP-NFYVDPE-------KQAVRYAYEAGNVEDDFYKDGKVARDADIAL- 204

Query: 195 FLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWT 254
              + + + PF + +GF KPH+P   PK+Y       +   P     P +M  ++   W 
Sbjct: 205 ---REHQNDPFLMFVGFSKPHLPFNAPKKYWDMYQRDQFTVPSR-KTPDNMFRLALTKWN 260

Query: 255 DVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTI 310
           ++R    I +       G    + T  +  +YYA   Y+D  +G +L+ +D     + T 
Sbjct: 261 ELRMYGGIPK------EGYTDDELTKTLIHAYYATVSYMDAQVGKVLNTLDELGLRENTT 314

Query: 311 IVLTSDHGWSLGENGLWAKYSNFDYALKVPLI----FKSPKLIPTVVHEP-VELIDIFPT 365
           ++  SDHG+ LGE G W K++N +   +VPLI     + PK    V  +  VE +DIFPT
Sbjct: 315 VIFMSDHGYKLGEYGAWNKHTNMELDTRVPLIISQALEEPKRKSGVTSDALVEYVDIFPT 374

Query: 366 LVDLTKL 372
           + +   L
Sbjct: 375 IAETAGL 381


>UniRef50_A4APQ8 Cluster: Iduronate-2-sulfatase; n=3;
           Bacteroidetes|Rep: Iduronate-2-sulfatase -
           Flavobacteriales bacterium HTCC2170
          Length = 493

 Score =  155 bits (376), Expect = 3e-36
 Identities = 116/382 (30%), Positives = 181/382 (47%), Gaps = 35/382 (9%)

Query: 19  DVETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSL 74
           D +   NILFI +DDLR       +   + PN++ L   G  FNN F Q   C  SR SL
Sbjct: 22  DKQEQPNILFIAVDDLRPEIGAYGNDIAFTPNMDKLANEGTVFNNHFVQVPTCGASRYSL 81

Query: 75  LTGRRPDS---LRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHP------ 125
           LTG RP     L      +   D+S  +   T I    K +GY T  +GK+ H       
Sbjct: 82  LTGMRPSKPIHLSNRAIEAELSDKSETKVPETFI-HHLKRNGYYTVGIGKISHSADGFLY 140

Query: 126 GKSSNFTD--DYPYSWSEYPYHP---PTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPG 180
           G +   +D  + P+SW+E  ++     T           +  + L++N + P        
Sbjct: 141 GYTEEISDKRELPHSWNELVFNSGKWKTGWNAFFGYANGENRQSLDKN-VKPYEAGNVKD 199

Query: 181 QSLPDLQSLDYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEP 239
               D  + + +I  L++ +   +PFFLA+GF KPH+P   PK+Y       ++     P
Sbjct: 200 DGYVDGLTAELSISKLRQLKMKDEPFFLAVGFFKPHLPFNAPKKYWDLYDRDEIPLSPNP 259

Query: 240 NIPKDMPLVSWHP---WTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDEL 296
            IP+++ L S H    +   +  D+   L+       +  ++  K+R SY AA  Y+D  
Sbjct: 260 EIPENVHLKSLHESGEFNQYKLTDETAHLSEP-----ITDEYAKKLRHSYLAAVSYVDAQ 314

Query: 297 IGILLSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP--KLIP 350
           IG +L  +      + TI+VL  DHGW LG+  +W K++ F+ ALK  LI K P  KL  
Sbjct: 315 IGKVLDELQTLGLEKNTIVVLWGDHGWHLGDQRIWGKHTLFENALKSALIVKDPKGKLKK 374

Query: 351 TVVHEPVELIDIFPTLVDLTKL 372
             V+  VE +DI+P+L++ + +
Sbjct: 375 GSVNSIVETVDIYPSLLEFSNI 396


>UniRef50_A6DSH1 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate-2-sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 462

 Score =  155 bits (375), Expect = 3e-36
 Identities = 141/498 (28%), Positives = 223/498 (44%), Gaps = 79/498 (15%)

Query: 21  ETPKNILFILIDDLR----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           E   N+LFI+ DDL           V  PN++ L      F+ A++Q  LC PSRNS+L+
Sbjct: 20  ENKMNVLFIMSDDLNVDIASYGHPIVKTPNLDKLRSKSVLFSQAYSQYPLCNPSRNSILS 79

Query: 77  GRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
           G  P +          R  +    + TT+P+ FK+ GY+  S GK+FH     ++T    
Sbjct: 80  GMYPGTSGCLSNADQLRKTAP---DITTLPEAFKKQGYEVISTGKIFHHEDPQSWTGITN 136

Query: 137 YSWSE-YPYHPPTEMYKDA-----KVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLD 190
               + +P       Y+ A      +   +   + E   +   SV  +    L D ++  
Sbjct: 137 LRTGKLHPQGKDYNFYRPAFDERKTIGEGRNLTEGELGFMTWRSVTEKE-DILFDSRTAR 195

Query: 191 YAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVS 249
           + +  L+K     KPFFL +GF +PH P   PK +    P+  +  P+ P     +P+++
Sbjct: 196 WTMQHLEKLAEDEKPFFLGVGFSRPHDPFFAPKRFFDMYPMESIKLPETPQNASKVPMMA 255

Query: 250 WHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD---- 305
           ++   DV KR           F  M T+  L+  +SYYA+  Y+DE +G++L  ++    
Sbjct: 256 YY---DVFKR----------AFDKMDTQKRLEFVRSYYASISYMDEQLGLVLDKLEALNL 302

Query: 306 MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTV--VHEPVELIDIF 363
              T++V  SDHG+ +GE G + K   F+ + + PL+  +PKL  +V  V + VE ID+ 
Sbjct: 303 SNNTLVVFISDHGYQVGEKGYFNKTLLFERSCRAPLMISNPKLKSSVNKVDKIVEFIDVL 362

Query: 364 PTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQK 423
           PT+ ++T  S   PK            EG+SL+P ++      +  AIS           
Sbjct: 363 PTITEIT--SVPTPKTA----------EGRSLIPLMKGKKVEWKEEAISYV--------- 401

Query: 424 NSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNL 483
           N+D+           SIRT+RYR   W                   LYDH  DP E  N 
Sbjct: 402 NADR-----------SIRTERYRLINWRGQKEA-------------LYDHQRDPGEHFNQ 437

Query: 484 FLVSKYKNIAKVLSIRLR 501
               +YK + K L  +L+
Sbjct: 438 VDNPEYKEVLKRLRSKLK 455


>UniRef50_Q7UJQ7 Cluster: Iduronate-2-sulfatase; n=2;
           Planctomycetaceae|Rep: Iduronate-2-sulfatase -
           Rhodopirellula baltica
          Length = 571

 Score =  154 bits (374), Expect = 5e-36
 Identities = 137/487 (28%), Positives = 217/487 (44%), Gaps = 70/487 (14%)

Query: 25  NILFILIDDLRHL----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+L IL+DDL+       D     PNI+ L   G  F  A+  QA+CAPSR +L+ G   
Sbjct: 101 NVLLILVDDLKPALGCYGDSIAKTPNIDSLANRGMRFEMAYCNQAVCAPSRFTLMLGSHS 160

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFF-KEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
            S  LY   S  R       +  T+PQ F K+ GY T S+GK FH G   N  D   +S 
Sbjct: 161 TSTGLYGLGSQLRQIIP---DAVTMPQHFAKQGGYRTESLGKTFHIGHG-NHGDPESFSV 216

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKK---LERNLICPV-SVKRQPGQSLPDLQSLDYA--- 192
             +      E  + A     + T++       ++  + ++ R      PD +  DYA   
Sbjct: 217 PHFK-EKVIEYLEPASTDGGQLTREEAYFTNQMLGRIKTLPRGAAYESPDAKDEDYADGR 275

Query: 193 --------IDFLKKRNGSK--PFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIP 242
                   +   K+R  ++  PFF+A GF +PH+P   P++Y      + +  P    +P
Sbjct: 276 VAAETIQRLQAAKQRQKTEGTPFFIASGFARPHLPFSAPQKYWDLYDPASLPMPTHETLP 335

Query: 243 KDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLS 302
            D P V+     ++     +     T P      +    +   YYA+  Y+D  IG ++ 
Sbjct: 336 VDAPKVAGKRGGEISNYKPVP----TEPNADFDDELKRNLIHGYYASVSYVDAQIGKVIK 391

Query: 303 YVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVHEP 356
            +D    +  TI+VL  DHG+ LG+ G+W K++N++ A ++P++  +P +    +   + 
Sbjct: 392 ELDRLELLDNTIVVLWGDHGFHLGDLGIWTKHTNYEQANRIPILITAPGVTQPGSSTKQL 451

Query: 357 VELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPR 416
            E +DIFPTL +L  L            +     +G SLVP ++++S  +   A      
Sbjct: 452 AESVDIFPTLSELAGLP---------APSGPQPIDGVSLVPVLKDSSARVRDHAY----- 497

Query: 417 PSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIID 476
              YP++            +G SIRT+RYR  EW +                ELYD+  D
Sbjct: 498 -HAYPKRQ-----------LGRSIRTERYRLVEWKAFDGKGDT-------AYELYDYQTD 538

Query: 477 PIESKNL 483
           P E+KNL
Sbjct: 539 PNETKNL 545


>UniRef50_A3HTC6 Cluster: Choline sulfatase; n=1; Algoriphagus sp.
           PR1|Rep: Choline sulfatase - Algoriphagus sp. PR1
          Length = 499

 Score =  153 bits (372), Expect = 8e-36
 Identities = 116/364 (31%), Positives = 173/364 (47%), Gaps = 30/364 (8%)

Query: 25  NILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NI+FI  DDL           +V  PNI+ L   G  F NA AQ  LC PSR S+LTG R
Sbjct: 31  NIVFIASDDLNDWIGVLNGHPQVKTPNIDRLANRGTLFTNAHAQAPLCNPSRVSILTGLR 90

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
           P +  +Y      R+    +    T+PQ+F++ GY T S GK+FH G +          W
Sbjct: 91  PTTTGIYGLAPRHREVERTK-EVVTLPQYFEKRGYRTLSTGKIFHGGITPTERAIEFQDW 149

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK-- 197
                H P    K  K   +     L    I PV    +    + D +   +A++ +   
Sbjct: 150 GPDGGHRPFPPSKIVKAPLDMIDHPLIDWGIYPV----EHDSIMDDYKVASWAVEQINEI 205

Query: 198 -KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEP-NIPKDMPLVSWH-PWT 254
            K   S PFFLA+GF+KPH+PL   +++    P  ++  P  P     D+P  +W+  W 
Sbjct: 206 GKGGDSNPFFLAVGFNKPHVPLYTSQKWFDLYPKDEIILPLAPFGDRNDIPDFAWNLHWY 265

Query: 255 DVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTI 310
               R           + +   +W  K+R +Y A   ++D  +G +L  ++     + TI
Sbjct: 266 LPEPR---------LSWLIANQEWENKVR-AYLATISFMDAQVGRVLDALEENNLTENTI 315

Query: 311 IVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP-TVVHEPVELIDIFPTLVDL 369
           IV  SDHG+ LGE  +  K S ++ +  VPLIF  P +    +  +PVEL+DI+PTLV++
Sbjct: 316 IVFWSDHGYHLGEKDITGKNSLWERSTHVPLIFAGPGVSKGAISSQPVELLDIYPTLVEM 375

Query: 370 TKLS 373
             LS
Sbjct: 376 ALLS 379


>UniRef50_Q1YTH2 Cluster: Sulfatase family protein; n=1; gamma
           proteobacterium HTCC2207|Rep: Sulfatase family protein -
           gamma proteobacterium HTCC2207
          Length = 504

 Score =  151 bits (366), Expect = 4e-35
 Identities = 142/516 (27%), Positives = 227/516 (43%), Gaps = 68/516 (13%)

Query: 16  LTSDVETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSR 71
           + SDV+ P N+LFI+IDDLR          V  PNI+ L +    F NA+    +C  SR
Sbjct: 19  VASDVK-PANVLFIMIDDLRPELGAYGSTAVKSPNIDSLARESVVFANAYVNVPVCGASR 77

Query: 72  NSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNF 131
            S+++G RP   R   + +   + + G     T+  + K+ GY + S+GK+ H      F
Sbjct: 78  ASMMSGIRPTEKRFVGYQARIDEDAKGA---ETLFGYLKKQGYYSESIGKILH------F 128

Query: 132 TDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLD- 190
           ++D    WS  P++P  ++ +     RN ++ +   + +   +        +PD    D 
Sbjct: 129 SEDSKAGWSTPPWNPKAKIKRIGH--RNYQSAENIASFLKDRTGPAYEAADVPDNHYFDG 186

Query: 191 ----YAIDFLKKRNG-SKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDM 245
                A+  L+  +   +PFF+A+GF KPH+P   P  Y        +     P +P   
Sbjct: 187 MIADQAMASLESASQRDQPFFMAVGFLKPHLPFTVPLRYWDLYNEEDIDLASNPLMPVGA 246

Query: 246 PLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD 305
           P  + H W ++RK + I +     P  V P     K+   Y A+  Y D  +G LL+ + 
Sbjct: 247 PREAIHSWGELRKFEGISKS----PHPV-PDAMAKKLVHGYLASVSYSDAQVGKLLTKLK 301

Query: 306 M----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELID 361
                + TI++L  DHG+SLGE+GLW K+S FD A + PLI K P  + T       L+ 
Sbjct: 302 QLNLDENTIVILAGDHGFSLGEHGLWVKHSPFDVATRTPLIVKLPSAL-TDTSPMGRLLK 360

Query: 362 IFPTLVDLTK----LSDEIPKCLN-----------HKDTSQLCFE--GKSLVPFIENNSN 404
              +   L+K     S+E+   LN             D      E  GK  +P ++  S 
Sbjct: 361 NSLSKSTLSKSPLSKSNELTPSLNPGVGIAEGLVEFVDIFPTVLELLGKPKLPQLQGESF 420

Query: 405 GLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXX 464
           G +    S   + +V+P+ ++      D+      I+T RY  TEW              
Sbjct: 421 GSQLLDSSAPGKAAVFPRWHA-----ADV------IKTDRYAMTEWFDRQGQVTARM--- 466

Query: 465 XYGIELYDHIIDPIESKNLFLVSKYKNIAKVLSIRL 500
                L+DH+ DP E+ NL     +K +   L  +L
Sbjct: 467 -----LFDHLNDPKETVNLADNKDFKTLVAELHEQL 497


>UniRef50_A3ZMC3 Cluster: Iduronate sulfatase; n=2;
           Planctomycetaceae|Rep: Iduronate sulfatase -
           Blastopirellula marina DSM 3645
          Length = 558

 Score =  149 bits (360), Expect = 2e-34
 Identities = 120/408 (29%), Positives = 189/408 (46%), Gaps = 50/408 (12%)

Query: 16  LTSDVETPKNILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPS 70
           LTS  + P N+LFI +DDL           +   PNI+ L   G  F  A+     C PS
Sbjct: 18  LTSAADPP-NVLFIAVDDLNDWVGCLGGHPQTRSPNIDRLAAQGVLFERAYCSAPACNPS 76

Query: 71  RNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSN 130
           R SLLTG  P +  +Y     WR       +  T+PQF++++GYD    GK+FH     +
Sbjct: 77  RASLLTGIAPSTSGVYHNNQPWRP---AMPDAVTLPQFYQQNGYDVLGCGKIFH----GS 129

Query: 131 FTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLD 190
           + +D    W EY         +        KT   +     PV  +      + D Q +D
Sbjct: 130 YREDS--GWDEYLKQTGDPKPQQLPANGIPKTSHFDWG---PVDAQ---DAEMSDYQMVD 181

Query: 191 YAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSW 250
           +AID L +++  KP FLA G ++PH+P   P+EY +  P+ ++  P+      D+  V  
Sbjct: 182 WAIDQLGQKH-DKPLFLACGIYRPHLPWFVPQEYFEHFPLDQIQLPQIK--ADDLADVPE 238

Query: 251 HPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----M 306
                 +   D +++  T  +         K  Q Y A+  + D  +G L++ ++     
Sbjct: 239 AGVKIAKPNGDHKKVTSTDNYA--------KAVQGYLASIEFADAQVGRLIAALEASPYA 290

Query: 307 QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVH--EPVELIDIFP 364
             TIIVL  DHGW LGE   W K+S ++ A +VPL+  +P +     H    V L+D++P
Sbjct: 291 DNTIIVLWGDHGWHLGEKQHWRKFSLWEEADRVPLLIIAPGMTKPNQHCERTVTLLDLYP 350

Query: 365 TLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAIS 412
           TL +L  L+   PK +          EG+SL P +++ +   +  AI+
Sbjct: 351 TLAELCGLT--APKVV----------EGQSLAPLLKDPAAAWDRPAIT 386


>UniRef50_UPI0000E11068 Cluster: iduronate-sulfatase (partial) and
           sulfatase 1 precursor; n=1; alpha proteobacterium
           HTCC2255|Rep: iduronate-sulfatase (partial) and
           sulfatase 1 precursor - alpha proteobacterium HTCC2255
          Length = 490

 Score =  145 bits (352), Expect = 2e-33
 Identities = 108/366 (29%), Positives = 176/366 (48%), Gaps = 37/366 (10%)

Query: 25  NILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N+L +++DDL               PNI+ L + G  F+NA A   LC PSR S++TG  
Sbjct: 34  NVLMLIVDDLNDWIGPLGGHPNTKTPNIDRLARQGTVFSNAHAPAPLCGPSRASVMTGLA 93

Query: 80  PDSLRLYDFYSYWR-DRSNGQGNFTT-IPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPY 137
           P +  +Y         R+N +   +  + ++F++HGY T +VGKVFH G + N  D++  
Sbjct: 94  PATTGIYGHVKDIDIKRANPKAAESVFLSEYFRKHGYYTAAVGKVFHQGIAPNSFDEFGG 153

Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
            +  +    P E +K      +K+T                  + +PD  +  +    L 
Sbjct: 154 RYKGFG-PSPDERFK----WHDKRTNT-------DWGAFPDDDEQMPDYDAAQWLAKQLG 201

Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVR 257
            RN +KPFF+A GF +PH P   P+++    P+  +  P  P +P D+  V      D+ 
Sbjct: 202 -RNHNKPFFMAGGFLRPHAPWYVPQKWFDIHPLEDIVLP--PFLPNDLDDVP-----DIA 253

Query: 258 KRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVL 313
           K      +  T  + +   +W   I Q Y A+  ++D  +GI+L  ++       T +VL
Sbjct: 254 KAVSAHPMMPTTEWALENNEWK-NIVQGYLASVSFVDSCVGIVLDALENSPYADNTAVVL 312

Query: 314 TSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKL-----IPTVVHEPVELIDIFPTLVD 368
             DHG+SLGE   +AK S ++ A + PLI   PK         VV++PV L+D++PTL+ 
Sbjct: 313 WGDHGYSLGEKSKFAKMSLWERATRTPLIITPPKNKVSGDANNVVNQPVSLLDLYPTLIK 372

Query: 369 LTKLSD 374
           +  L +
Sbjct: 373 ICGLPE 378


>UniRef50_A6L183 Cluster: Iduronate 2-sulfatase; n=2;
           Bacteroides|Rep: Iduronate 2-sulfatase - Bacteroides
           vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154)
          Length = 477

 Score =  144 bits (350), Expect = 4e-33
 Identities = 148/497 (29%), Positives = 208/497 (41%), Gaps = 76/497 (15%)

Query: 25  NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+LF++ DD+R        K+V  PNI+    +G  F NA+    +   SR SLLTG  P
Sbjct: 29  NVLFLMADDMRPELGCYGVKEVKTPNIDRFAASGLLFQNAYCNIPVSGASRASLLTGVYP 88

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
                +  YS +  +         I ++F  HGY T S GKVFH         D+  SWS
Sbjct: 89  HYPDRFVNYSAYASKDCPTA--IPISRWFTSHGYYTISNGKVFH------HLSDHANSWS 140

Query: 141 EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQ-----SLPDLQ------SL 189
           E PY    + Y       NK    +       ++ K   G       +PD        +L
Sbjct: 141 EPPYRKHPDGYDVYWAEYNKWELWMNEASARTINPKTMRGPFCEWAEVPDTAYDDGKLAL 200

Query: 190 DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVS 249
               D  + +   KPFF+A GF KPH+P   PK+Y       K+        PKD+P   
Sbjct: 201 KAIADLKRLKEQGKPFFMACGFWKPHLPFNAPKKYWDLYDREKIPVANNRFRPKDLP--- 257

Query: 250 WHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD---- 305
                +V+   +I     T         +  + +  YYA   Y+D  IG +L  +D    
Sbjct: 258 ----NEVKNSTEIYAYARTTT--ADDISFQKEAKHGYYACLSYVDAQIGKVLDALDELGL 311

Query: 306 MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIFPT 365
              TI+VL  DHGW LGE+    K++  D +  VPLI + P L        VE +D++PT
Sbjct: 312 ANNTIVVLLGDHGWHLGEHNFLGKHNLMDRSTHVPLIVRVPGLKKGKTKSMVEFVDLYPT 371

Query: 366 LVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNS 425
           L +L  L   IPK       +QL  +G S VP + N    L+A    Q     VY Q   
Sbjct: 372 LCELCHL--PIPK-------NQL--DGTSFVPILTN----LKAKIKDQ-----VYIQWEG 411

Query: 426 DKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFL 485
                 D T+      + RY Y EW               +   L+DH IDP E+KN   
Sbjct: 412 G-----DNTV------SNRYNYAEW---------KQKEKIHSRMLFDHHIDPEENKNRVN 451

Query: 486 VSKYKNIAKVLSIRLRS 502
             KY++    LS  L++
Sbjct: 452 ERKYRSEINKLSSFLKA 468


>UniRef50_A6DNH1 Cluster: Choline sulfatase; n=2; Lentisphaera
           araneosa HTCC2155|Rep: Choline sulfatase - Lentisphaera
           araneosa HTCC2155
          Length = 470

 Score =  144 bits (350), Expect = 4e-33
 Identities = 107/387 (27%), Positives = 180/387 (46%), Gaps = 44/387 (11%)

Query: 25  NILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N+L I +DDL           +   PN++ L   G  F N   Q  +C PSR S++T   
Sbjct: 26  NVLLIAVDDLNDWIGVLGGHPQAKTPNMDRLANRGVLFTNTQCQSPVCNPSRGSMMTSLY 85

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
           P +  +Y            +G+   +P+ F+  GY   + GK+FH  ++  +  +Y  S+
Sbjct: 86  PSTTGIYFLNPSVGTSPKAKGHLV-MPKRFEAEGYHVSAAGKLFHNQENKKYFKEYGGSF 144

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR 199
             +   P             KK      + +    V  +  + +PD++   +  + L  R
Sbjct: 145 GGFGPIP------------KKKITSFPGHPLWDWGVYPERDEQMPDVKIAAWGKERLA-R 191

Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPK-EPNIPKDMPLVSWHPWTDVRK 258
           +  +PFF+ IGF++PH+P   P+++    P+  V  PK   N  + +P        D+ +
Sbjct: 192 DYDQPFFMGIGFYRPHVPQFAPQKWFDMYPLESVQMPKMRKNDIEGIPQYG----VDLTR 247

Query: 259 RDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQ----KTIIVLT 314
              +     T+ + V+  K   K+ QSY A   ++D  +G +L  +D       T +VL 
Sbjct: 248 EKHVAP---TYEW-VIENKEEKKLVQSYLACVSFVDAQVGKILDALDASPHKDNTYVVLY 303

Query: 315 SDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIFPTLVDLTKLSD 374
           SDHG+ LGE   +AK S ++   +VP++   P + P V H+P +L+DI+PTL++LT L  
Sbjct: 304 SDHGFHLGEKERYAKRSLWEDGARVPMMISGPGIKPGVTHKPTQLLDIYPTLLELTGLKS 363

Query: 375 EIPKCLNHKDTSQLCFEGKSLVPFIEN 401
           + PK            EG SLVP + N
Sbjct: 364 D-PK-----------LEGNSLVPLLRN 378


>UniRef50_Q8A3P0 Cluster: Iduronate 2-sulfatase; n=2; Bacteroides
           thetaiotaomicron|Rep: Iduronate 2-sulfatase -
           Bacteroides thetaiotaomicron
          Length = 473

 Score =  144 bits (349), Expect = 5e-33
 Identities = 121/428 (28%), Positives = 190/428 (44%), Gaps = 48/428 (11%)

Query: 5   VNIILLNGDRVLTSDVETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNA 60
           V++I+L+    L        N+L I+ DD+R        + +  P ++ L +    F NA
Sbjct: 10  VSVIVLSSSVHLHGQ-NNKMNVLLIIADDMRPELGCYGIEDIVTPRLDSLARYATVFQNA 68

Query: 61  FAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVG 120
           +    +   SR SL TG  P     +  +    ++   +    ++P+ FK++GY   S G
Sbjct: 69  YCNIPVSGASRASLFTGMYPRYPNRFTAFDASAEKDCPEA--LSLPECFKKNGYYVVSNG 126

Query: 121 KVFHPGKSSNFTDDYPYSWSEYPYHPPTEMY-KD-AKVCRNKKTKKLERNLICPVSVKRQ 178
           KVFH     N TD +  SWSE P+    + Y KD A+  + +  +  E +        R 
Sbjct: 127 KVFH-----NITD-HADSWSEAPWRVHPDGYGKDWAEYNKWELWQNEESSRYVHPKTLRG 180

Query: 179 PGQSLPDLQSLDYA---------IDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMP 229
           P     D+    Y           D  +     KPFFLA GF KPH+P   PK+Y     
Sbjct: 181 PFCESADVADTTYIDGRVAQKTIADLRRLHKKEKPFFLACGFWKPHLPFNAPKKYWDLYR 240

Query: 230 ISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAA 289
             ++H  + P  PK +P         V    +IR              +  + +  YYA 
Sbjct: 241 REEIHLAQNPYRPKALP-------KQVTSSGEIRGYGKFVT--TKDETFQREAKHGYYAC 291

Query: 290 ALYIDELIGILLSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKS 345
             YID  IG++L  +D     + TI+V+  DHGW LGE+G W K++  ++A + PLI + 
Sbjct: 292 VSYIDAQIGLILDELDRLGLSENTIVVILGDHGWHLGEHGFWGKHNLMNHATRAPLIVRV 351

Query: 346 PKLIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNG 405
           P          VE +DI+PTL +L  +   +PK        QL  +GKS VP ++++   
Sbjct: 352 PHCRGGKAKGIVEFVDIYPTLCELCGV--PMPK-------DQL--QGKSFVPILQDSGKK 400

Query: 406 LEAFAISQ 413
            + +A  Q
Sbjct: 401 TKQYAFIQ 408


>UniRef50_A6DG72 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate-2-sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 468

 Score =  144 bits (349), Expect = 5e-33
 Identities = 127/428 (29%), Positives = 191/428 (44%), Gaps = 68/428 (15%)

Query: 24  KNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           KN+LFI+ DDL+        DK    PN++ L      F+ A+ Q   C PSR SL+  R
Sbjct: 29  KNVLFIIADDLKASVLACYGDKICQTPNLDKLASQSIVFDRAYCQGLSCGPSRTSLMHSR 88

Query: 79  RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH---PGKSSNFTD-- 133
              S                +G    +P+  K +G+ T  VGK++H   P    +  D  
Sbjct: 89  YLGS----------------EG--INLPEHLKNNGWYTVRVGKIYHMRVPYDIIHGIDGQ 130

Query: 134 DYPYSWSEYPYHPPTEMYKDAK-VCRNKK--TKKLE-------RNLICPVSVKRQPGQSL 183
           D P SW+E       E +      C NK   TK L+       +N +    +    G   
Sbjct: 131 DIPSSWTEKFNSKGAESHTPGDYACLNKNIFTKSLKNRESSGMKNRMFVSVISEGDGSDQ 190

Query: 184 PDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPK 243
           PD++S +  I+ L +R  ++PFF+A G  +PH P   PKE+ +  P  K+  P+  N P 
Sbjct: 191 PDVKSAEKTIELLNQRK-NEPFFIATGLVRPHYPNVAPKEFFQNYPWEKIDLPELRN-PT 248

Query: 244 DMPL-VSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLS 302
            + +  + HP          R  N     G  P     ++  +YYA   ++D  IG +L 
Sbjct: 249 SLGIPAAGHP----------RITNSNNSIGKYPDNQK-RMWSAYYATVEFMDRQIGRILD 297

Query: 303 YVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVE 358
            VD       T I+  SDHG+ LGE+G W K +  +   +VPLI   P L P  ++E  E
Sbjct: 298 EVDRLGLKSNTAIIFLSDHGYHLGEHGFWQKNNLHEEVTRVPLIAYIPGLAPRRINEVTE 357

Query: 359 LIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPS 418
           L+DI+P+L +L  L    PK +          +GKS +PF++N +      A+S  P   
Sbjct: 358 LVDIYPSLTEL--LGVYKPKTV----------QGKSFLPFLKNKTEDFRNSALSLMPGKK 405

Query: 419 VYPQKNSD 426
            Y  +  D
Sbjct: 406 GYSIRTED 413


>UniRef50_Q7UER3 Cluster: Iduronate-2-sulfatase; n=1; Pirellula
           sp.|Rep: Iduronate-2-sulfatase - Rhodopirellula baltica
          Length = 492

 Score =  142 bits (345), Expect = 1e-32
 Identities = 110/373 (29%), Positives = 174/373 (46%), Gaps = 31/373 (8%)

Query: 21  ETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           E PKN+L I +DDLR          V  PNI+ L   G  FN  F Q   C  SR ++LT
Sbjct: 41  EKPKNVLLICVDDLRPELGCYGADYVSSPNIDSLAAKGIQFNRHFVQAPTCGASRFAMLT 100

Query: 77  GRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKV-FHPGK--SSNFTD 133
           G    S     F    +   +      ++P++F++HGY + SVGKV  HPG    +++ +
Sbjct: 101 GCYGPSGNHALFQRAKKIAKDPTSVTPSMPRWFRDHGYTSVSVGKVSHHPGGRGGADWNE 160

Query: 134 D----YPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPG--QSLPDLQ 187
           +     P +W  +    PT  ++  +   +       R     + V +  G     PD  
Sbjct: 161 EAEIEMPGAWDRHLM--PTGPWQHPRGAMHGLADGEIRKDASQMDVFQSAGGEAKYPDDL 218

Query: 188 SLDYAID---FLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKD 244
            L+ +++    L + + +KPFFLA+GF +PH+P   P EY+K    S +   + PN P  
Sbjct: 219 ILETSLNELTTLAEDSANKPFFLAVGFIRPHLPFGAPAEYMKPYRQSVLPMIEHPNKPFG 278

Query: 245 MPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV 304
               +WH      +  +  R N          ++   +R+ Y A   Y D  +G +L  +
Sbjct: 279 Q--TTWH------RSGEFMRYNRWGKDPNQDAEFADAVRRHYAACVSYADANVGEVLKQL 330

Query: 305 D----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLI-PTVVHEPVEL 359
           D     + T++V+  DHGW LGE+ +W K++ F+ +L  PLI   P +   +     VE 
Sbjct: 331 DELGLRESTVVVVWGDHGWHLGEHAIWGKHALFEESLHSPLIIHDPSMSNASQTDAIVET 390

Query: 360 IDIFPTLVDLTKL 372
           ID+FPTL +L  L
Sbjct: 391 IDVFPTLCELANL 403


>UniRef50_A6C6J6 Cluster: Iduronate-2-sulfatase; n=2; Bacteria|Rep:
           Iduronate-2-sulfatase - Planctomyces maris DSM 8797
          Length = 492

 Score =  142 bits (345), Expect = 1e-32
 Identities = 112/379 (29%), Positives = 172/379 (45%), Gaps = 35/379 (9%)

Query: 17  TSDVETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRN 72
           TSD   P N+L I IDDLR          V  P+++ L   G  F N F Q   C  SR 
Sbjct: 28  TSDNSQP-NVLLIAIDDLRTELGCYGLPYVQSPSLDQLASEGVLFTNHFVQVPTCGASRY 86

Query: 73  SLLTGRRP--DSLRLYDFYSYWRDRS---NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGK 127
           +LLTGR P    +   +   Y  D +   N      T+P+ F+  GY T  +GK+ H   
Sbjct: 87  ALLTGRSPRNSGVTRKNQAFYQGDSALSVNQTAGAQTMPELFRRSGYQTTCIGKISHTAD 146

Query: 128 SSNFT--------DDYPYSWSEY--PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKR 177
              F         D+ P++W E   P+      +       N ++++    +   +  K 
Sbjct: 147 GRVFEYNGTGDGRDELPHAWDELATPFGSWKRGWGIFFAYANGRSREDGSGIRDLMEFKV 206

Query: 178 QPGQSLPDLQSLDYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRP 236
           +  + LPD      AI+ L++ + G KPFFL +GF KPH+P   PK+         V  P
Sbjct: 207 EQDEELPDGLLARQAIEKLREYKEGGKPFFLGLGFFKPHLPFVAPKQDWDAF--ENVEIP 264

Query: 237 KEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDEL 296
             P+ P+      WH   +    D       T P      +    +R+ Y A   Y D  
Sbjct: 265 PVPH-PEKPESAYWHKSGEFYNYD--MEFEKTRPLSREARE---NVRRGYLACVRYTDRQ 318

Query: 297 IGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTV 352
           +G +L+ +D     + TI+++  DHGW LG++ LWAK++  + ALK  L+ ++P +    
Sbjct: 319 VGKVLTALDELGMRENTIVIVWGDHGWFLGDSALWAKHAPLERALKSTLMIRAPGVAEAG 378

Query: 353 VHEP--VELIDIFPTLVDL 369
           +     VE +DI+PTL+DL
Sbjct: 379 LKSAALVETVDIYPTLIDL 397


>UniRef50_A7ADK4 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 478

 Score =  141 bits (341), Expect = 5e-32
 Identities = 119/407 (29%), Positives = 192/407 (47%), Gaps = 44/407 (10%)

Query: 24  KNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           +NILFI+ DDLR        K++  PNI+        F+ A+   A+   SR SLLTG R
Sbjct: 30  QNILFIVCDDLRPELGCYGRKQIKSPNIDRWATQSVLFDRAYCNIAVSGASRASLLTGLR 89

Query: 80  PDSLRLYDFYSYWRDRSNGQ-GNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNFTDDY- 135
           P      +    W  R++    +  TI + F++ GY T + GK++H     S  + DD  
Sbjct: 90  PTK----NLLQTWNARTDVDVPDAVTIQKCFRDAGYITIANGKIYHHQDEASMKYWDDVM 145

Query: 136 -PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAID 194
            P   +   YH    +   A + + +KT K  R           P +   D Q  D +I 
Sbjct: 146 PPVPGTAMGYHSDENL---ALMQKQQKTGKGRRGYFYEHG--DFPEKDYLDWQIADKSIQ 200

Query: 195 FLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPK--DMPLVSWH 251
            LKK +   KPFFLA+GF +PH+P   P++Y      S++  P+   +    ++P  +  
Sbjct: 201 DLKKLKKQEKPFFLAVGFIRPHLPFVVPQKYWDMYDHSEIEIPENYILKSGNNIPERALT 260

Query: 252 PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQ---- 307
            W+++R    I         G +  +    +   YYA+  ++D  IG LL  ++ +    
Sbjct: 261 NWSELRAYSGIPEQ------GPLDEETAKLMIHGYYASVSFVDAQIGRLLKTLEEEGLDK 314

Query: 308 KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKL-IPTVVHEPVELIDIFPTL 366
            T +VL  DHGW+LGE+G W K+S  +  L   LI  SP++  P    + VE +D++PT+
Sbjct: 315 NTTVVLIGDHGWNLGEHGTWCKHSIMNTCLHSTLIINSPEIKTPHRCEQIVEFVDLYPTM 374

Query: 367 VDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQ 413
            D   +  E P        +QL  EG SL+P +++     + + +S+
Sbjct: 375 CDAAGI--ERP--------AQL--EGTSLLPLLKSPEAKTKGYGVSR 409


>UniRef50_A6DKB6 Cluster: Iduronate sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 475

 Score =  140 bits (340), Expect = 6e-32
 Identities = 140/485 (28%), Positives = 215/485 (44%), Gaps = 84/485 (17%)

Query: 21  ETPKNILFILIDDLRHLSD-----KKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLL 75
           ++  NILFI IDD+   +       +   PN++ L K G  F NA      C+PSRN+LL
Sbjct: 20  QSAPNILFIAIDDMNDWTGFLGGHPQAQTPNMDSLAKEGVNFTNAHCSAPGCSPSRNALL 79

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY 135
            G  P +  LY FY +   +   Q  +T++P+  KE+ Y TY  GK+ H  K      D 
Sbjct: 80  YGIEPFNSGLYPFYEHEIHQDLHQ-KYTSLPRLLKENSYKTYGSGKIHHGPK------DD 132

Query: 136 PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDF 195
              W++Y Y P       AK    +  K  + +    +S    P +   D Q +DY ID 
Sbjct: 133 SREWTDY-YEPKNFKRLYAKGSGYQVGKSHKSSFRPTIS----PYEQHLDHQFVDYGIDI 187

Query: 196 LKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIP-KDMPLVSWHPWT 254
           L +++  KPFFLA+G  KPH+P   PK +   +P   +  P+  N   KD+P  +     
Sbjct: 188 LSQKH-DKPFFLAVGIVKPHLPFNAPKTFFDALP-EVIIAPEILNDDLKDVPKEA----K 241

Query: 255 DVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTI 310
           D  K  D R+             W   +R++Y A   + D  +G L+  ++       TI
Sbjct: 242 DFLKTRDDRQFK-------KDKAWE-DVRRAYLACISWADYNVGRLIKALEDSEYANNTI 293

Query: 311 IVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFK----SPKLIPTVVHEPVELIDIFPTL 366
           IVL SDHG+ +GE   + K++ ++ + +VP I K    +  L+     + V LI+I+ T+
Sbjct: 294 IVLWSDHGYHMGEKNTFRKFTLWEESTRVPFIIKDLRPNSNLMSANCTQAVSLINIYKTI 353

Query: 367 VDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSD 426
            D   +  + PK +          +G SL+P ++N    +    IS   R +        
Sbjct: 354 ADFANI--KTPKYV----------DGVSLIPQLQNVEEKILYPTISSWGRGN-------- 393

Query: 427 KPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLV 486
                      YS+R+  +RYT +                  ELY H  DP E KNL   
Sbjct: 394 -----------YSVRSDDWRYTRYHDGTE-------------ELYFHKTDPNEWKNLAQN 429

Query: 487 SKYKN 491
            +YKN
Sbjct: 430 PEYKN 434


>UniRef50_A6DJ24 Cluster: Iduronate-2-sulfatase; n=3; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate-2-sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 497

 Score =  138 bits (334), Expect = 3e-31
 Identities = 104/368 (28%), Positives = 175/368 (47%), Gaps = 27/368 (7%)

Query: 25  NILFILIDDLRHL-----SDKKVYLPNIN-FLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           N+LFI IDDL         +  V  PN + F    G +   A +   +C P+R++++TG+
Sbjct: 26  NVLFIAIDDLNDWIGPMGGNPAVKTPNFDKFFANGGMSMYKAHSPSTVCGPARSAIMTGK 85

Query: 79  RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
              +  +Y   +  ++    + +  TIP++F +HGY + S GK+FH   +    D   ++
Sbjct: 86  HCYNTGVYGNDTNLKNAPKAK-DLLTIPEWFSKHGYHSLSAGKIFHKHPTEKEIDHGQWA 144

Query: 139 WSEYPYHPPTEMYKDAKVCRN-------KKTKKLERNLICPVSVKRQPGQSLPDLQSLDY 191
           + E+         K      N       K+ K          +VK    Q + D +  D+
Sbjct: 145 FDEHHVIKGGLGAKSKAKPANGLLDINGKQMKGKGLEFDWGPTVKNDTTQ-MKDYKIADW 203

Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWH 251
           A++  +KR+  KPFF+A+GF KPH+P   P++Y    P+ K+  P+    P +  +    
Sbjct: 204 AVNQFQKRSFDKPFFMAVGFSKPHLPWFVPQKYFDMYPLDKIELPEIKENPHEKIVNEKG 263

Query: 252 PWTDVRK-RDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----M 306
            +   +  R+D +R      +GV  TK  L   Q+Y A   ++D+ +G LL  ++     
Sbjct: 264 EFIYGKAFREDSKRWGRAEKYGV--TKNAL---QAYMANVTFVDDCLGHLLDGLNNSPYA 318

Query: 307 QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT--VVHEPVELIDIFP 364
             TI+VL  DHGW LGE   + K   +  + +VPL+ K P + P        V LID++P
Sbjct: 319 DNTIVVLWGDHGWHLGEKKRFGKCLLWQESTRVPLMLKVPGVTPNNKRCDGVVNLIDLYP 378

Query: 365 TLVDLTKL 372
           TL +L  +
Sbjct: 379 TLSELCNI 386


>UniRef50_A6DGD4 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate-2-sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 574

 Score =  133 bits (321), Expect = 1e-29
 Identities = 120/419 (28%), Positives = 196/419 (46%), Gaps = 57/419 (13%)

Query: 25  NILFILIDDLR-----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N+LFI+ DDL      + S  +V  P++    K+  TF  A++   +CAPSR SL TG  
Sbjct: 22  NVLFIICDDLNDYVSAYESHPQVRTPHLKDFAKSAVTFKRAYSNNPVCAPSRASLFTGVY 81

Query: 80  P-DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTD----- 133
           P DS  L  F++ W ++   + N  TI + F+E+GY+    GK+ H  +   +T+     
Sbjct: 82  PHDSGNL--FWNKWYEQKTLKHN-KTIMELFRENGYNVIGTGKLLHHEQKQLYTEFKNKA 138

Query: 134 DYPYSW---SEYPYHPPTEM-----------YKDAKVCRNKKTKKLE------RNLICPV 173
           +Y   W    +   HP               Y   +   +K+TK         R +  P 
Sbjct: 139 NYGPYWLKDGKTVAHPDVPQPFAEIGAIDGSYGSIESAISKQTKNEHWFSGDWRFIKTPF 198

Query: 174 SVKRQPGQSLPDLQSLDYAIDFLKK--RNGS-KPFFLAIGFHKPHIPLKFPKEYLKQMPI 230
           + +       PD  +  +  + ++K  R+GS + FFL++GF +PH PL   ++Y    PI
Sbjct: 199 NFEGPNRDLTPDELNAKWVSERIEKLDRSGSDQAFFLSVGFVRPHTPLHVAQKYFDMFPI 258

Query: 231 SKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIR---QSYY 287
            ++  P+      D      H +TD+   D    +         P  W   I+   Q+Y 
Sbjct: 259 DQIQLPEILENDAD----DTH-YTDLFDADKKGLMYFDLLKKSYPN-WQEGIKAFTQAYL 312

Query: 288 AAALYIDELIGILLSYVDMQK----TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIF 343
           A+   +DE IG ++  +D  +    TI++ TSDHGW++GE     K S ++ + +VP I 
Sbjct: 313 ASIAAVDENIGRVIKTLDESRFKDNTIVIFTSDHGWNMGEKDYLFKNSPWEESGRVPFIV 372

Query: 344 KSPKLIP--TVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIE 400
           ++P++    +    PV LIDI+P+LVDL  L  +     N K+       G S+ PF+E
Sbjct: 373 RAPQIAKAGSKAEHPVSLIDIYPSLVDLCGLEGD-----NRKNERGAKLGGFSIRPFLE 426


>UniRef50_Q7UYA8 Cluster: Iduronate-2-sulfatase; n=1; Pirellula
           sp.|Rep: Iduronate-2-sulfatase - Rhodopirellula baltica
          Length = 745

 Score =  132 bits (318), Expect = 3e-29
 Identities = 106/363 (29%), Positives = 169/363 (46%), Gaps = 31/363 (8%)

Query: 25  NILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N+LFI +DDL         +     PN++   +    FNNA  Q ALC  SR S +TG  
Sbjct: 310 NVLFITVDDLNDWVGCLGGNPDAQTPNLDRFAQQSVLFNNAHCQVALCYASRASFMTGMY 369

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHP--GKSSNFTDDYPY 137
                +Y+  S  +   +       +P +F E GY T  +GK++H   GK + + +  P 
Sbjct: 370 ASKTGIYNNSS--KSARDAYHRAKQMPVWFGESGYRTMCMGKIYHNDHGKKAYWDEIGPK 427

Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
           +    P  P    +        K+  K  ++ +   ++  + G  +PD Q   + I+ L 
Sbjct: 428 TLRWGPEPPNGRQF-------TKRFGKDAQDSLAWAALDIEKG-GMPDEQIAAWGIEKLD 479

Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKE-PNIPKDMPLVSWHPWTDV 256
           +    +PFFL++GF+KPH P+  PK Y +Q     +  P    N   D+P +    W  V
Sbjct: 480 QEY-DQPFFLSLGFYKPHTPMTAPKRYFEQFDRDSLTLPNVLENDLDDVPEIG-RRW--V 535

Query: 257 RKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIV 312
             R  +        +   PT +  ++  +Y+A    ID+ IG +L  +D       TI+V
Sbjct: 536 LDRSKLIAEEAVKQYS--PT-YRRELVHAYHACVALIDDCIGQVLRKLDNSPYANNTIVV 592

Query: 313 LTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLT 370
           L SDHGW LGE   W K+  ++ + +  LI ++P    +  V    V LIDI+PTL +L 
Sbjct: 593 LCSDHGWHLGEKNHWRKWMPWEESTRSLLIVRTPDAAGSGQVCQRTVGLIDIYPTLAELC 652

Query: 371 KLS 373
           +LS
Sbjct: 653 ELS 655


>UniRef50_A4A280 Cluster: Iduronate-2-sulfatase; n=1;
           Blastopirellula marina DSM 3645|Rep:
           Iduronate-2-sulfatase - Blastopirellula marina DSM 3645
          Length = 475

 Score =  131 bits (317), Expect = 4e-29
 Identities = 112/389 (28%), Positives = 182/389 (46%), Gaps = 41/389 (10%)

Query: 7   IILLNGDRVLTSDVETPKNILFILIDDLRHLS-----DKKVYLPNINFLGKTGATFNNAF 61
           ++ L+   +L +D +   N+LFI+ DDL   S      ++   PNI+ L + G  F +A+
Sbjct: 11  VVTLSASSLLAADGKY--NVLFIISDDLSAESLSCYGHRECQTPNIDRLAQRGVKFTHAY 68

Query: 62  AQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK 121
            Q  +C PSR +L++G    ++ +       R   N  G+  ++ Q F++ GY    V K
Sbjct: 69  CQYPVCGPSRAALMSGLHAATIGVMGNGQSTRFTQN-LGDRASMSQHFRDQGYYAARVSK 127

Query: 122 VFH---PGKSSNFT--DDYPYSWSE-YPYHPPTEMYK-DAKVCRNKKTKK-LERNL---- 169
           ++H   PG  +  T  DD+  SW E +    P  M   DA    N+K  K  +++     
Sbjct: 128 IYHMRIPGDITAGTNGDDHAASWDERFNCQAPEWMSAGDAATYSNEKLNKDPDKHYGLGF 187

Query: 170 -ICPVSVKRQP-GQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQ 227
                +VK    G    D ++ D AI+ L+K    + FFLA+G  +PH+PL  P ++ + 
Sbjct: 188 GTAFYAVKASTDGAEQADHKAADKAIELLRKHKEER-FFLAVGMVRPHVPLVAPAKFFEP 246

Query: 228 MPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYY 287
               ++          ++PL     W D+ K    R    T     M  +       +YY
Sbjct: 247 YADGQM----------ELPLKVAGDWDDIPKAGISRNSKATG----MTLEGQRNTLSAYY 292

Query: 288 AAALYIDELIGILLSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIF 343
           AA  Y+D  +G +L  +      + T++V T+DHG+ LGE+  W K S  + +  +PLI 
Sbjct: 293 AAVAYMDYQVGRVLDELHQLGLDKNTVVVFTADHGYHLGEHDFWQKMSLHEESTHIPLIV 352

Query: 344 KSPKLIPTVVHEPVELIDIFPTLVDLTKL 372
             P   P VV+     IDI+PTL  L +L
Sbjct: 353 AIPGEQPKVVNGLAAQIDIYPTLAQLCEL 381


>UniRef50_A6DJE6 Cluster: Iduronate sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 574

 Score =  130 bits (315), Expect = 6e-29
 Identities = 139/527 (26%), Positives = 221/527 (41%), Gaps = 93/527 (17%)

Query: 3   YVVNIILLNGDRVLTSDVETPKNILFILIDDLRH----------LSDKKVY-LPNINFLG 51
           +++  ++ N       D + P N+LFI IDD+ H          + D   Y  PNI+ L 
Sbjct: 6   FLITALIFNSS--FAEDAKKP-NVLFISIDDMNHWISAMREYQAIYDYPAYKTPNIDRLL 62

Query: 52  KTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQG-NFTTIPQFFK 110
             G  F NA      C PSR S+ TG       +Y     W+     +  +  +I Q F+
Sbjct: 63  ARGMFFTNAHVPGGSCKPSRVSVFTGVAVSKHGVYRNPHTWQLAPMFKNRDDVSIMQRFR 122

Query: 111 EHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNL- 169
           + GY     GK FH     ++ D++  +    P     +M    +     K  ++ER   
Sbjct: 123 KEGYFVAGGGKNFHTYHPDSW-DEHIQTEERDPKGREADMVLKKQFHEANKAYEVERKRQ 181

Query: 170 ICPVSVKRQ-------------PGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHI 216
           +  +++K +             P +++PD   +DY I  L ++   +PFFL  GF KPH+
Sbjct: 182 MKALTIKDKSKADAIKWGPLDCPPEAMPDAFMVDYIIRKLNEKR-DQPFFLGCGFTKPHL 240

Query: 217 PLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPT 276
               P++Y    P+ ++            P+V  +   D+ K+        T  F V   
Sbjct: 241 AWAVPRKYFDMYPLDEI----------PTPVVKENDIDDLGKQGQSMAGGQTHDFMVKSG 290

Query: 277 KWTLKIRQSYYAAALYIDELIGILLSYVDMQ----KTIIVLTSDHGWSLGENGLWAKYSN 332
            WT  I Q Y A+  ++D+ IG LL  +D       TII+L SDHGW  G+ G W K++ 
Sbjct: 291 LWTSAI-QGYLASCTFVDDQIGRLLDAIDASPEKDNTIIMLWSDHGWHFGDKGHWKKFAT 349

Query: 333 FDYALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCF 390
           ++    +P+   +P L       H PV  ID++PTL+DL       P+            
Sbjct: 350 WEETTHIPMGIIAPGLSKAGQKTHRPVNAIDLYPTLLDLCGFEPN-PE-----------L 397

Query: 391 EGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGY-SIRTKRYRYTE 449
           +G SLVP ++N                   P +  D P L   +  GY ++RT+++R  E
Sbjct: 398 DGHSLVPLLKN-------------------PDREWDYPSLTTHS-RGYNTVRTEKWRLIE 437

Query: 450 WISXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVL 496
           +                 +ELYDH  DP+E  NL    +Y  +   L
Sbjct: 438 YPKDNE------------MELYDHSNDPLEHNNLINNPEYAKVVAEL 472


>UniRef50_A7LXD1 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides ovatus ATCC 8483|Rep: Putative
           uncharacterized protein - Bacteroides ovatus ATCC 8483
          Length = 479

 Score =  130 bits (313), Expect = 1e-28
 Identities = 109/367 (29%), Positives = 163/367 (44%), Gaps = 36/367 (9%)

Query: 25  NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+LFI+ DD+R          V  PN++ L  +G  F NA+    +   SR SLLTG  P
Sbjct: 33  NVLFIMADDMRPELGCYGVDVVKTPNMDRLAASGVLFQNAYCNIPVSGASRASLLTGVYP 92

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWS 140
                +  +S +  +   +     I  +F  +GY T S GKVFH         D+  SWS
Sbjct: 93  HYPDRFISFSAYASKDCPEA--IPISGWFTRNGYHTISDGKVFH------HISDHADSWS 144

Query: 141 EYPY--HPPT-----EMYKDAKVCRNKKTKKL--ERNLICPVSVKRQ-PGQSLPDLQSLD 190
           E PY  HP         Y   ++  N ++ K    + +  P       P  +  D +  +
Sbjct: 145 EPPYRNHPDGYDVYWAEYNKWELWMNSESGKTVNPKTMRGPFCESADVPDTAYDDGKLAN 204

Query: 191 YAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVS 249
            AI  LK+ +   KPFFLA GF KPH+P   PK+Y       ++        P+ +P   
Sbjct: 205 RAIRDLKRMKEAGKPFFLACGFWKPHLPFNAPKKYWDLYKREEIPLATNRFRPEGLP--- 261

Query: 250 WHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD---- 305
                 VR   +I               +  +++  YYA   Y+D  IG +L  +D    
Sbjct: 262 ----EQVRNSSEI--YAYARVADTSDIDFQREVKHGYYACLSYVDAQIGKVLDALDELGL 315

Query: 306 MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIFPT 365
              TI+VL  DHGW+LGE+    K++  + +  VPLI + P +        VE +D++PT
Sbjct: 316 SDNTIVVLLGDHGWNLGEHDFIGKHNLMNTSTHVPLIVRVPGMKKGKTKSMVEFVDLYPT 375

Query: 366 LVDLTKL 372
           L +L KL
Sbjct: 376 LCELCKL 382


>UniRef50_A6DSH0 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate-2-sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 462

 Score =  128 bits (308), Expect = 5e-28
 Identities = 109/362 (30%), Positives = 170/362 (46%), Gaps = 40/362 (11%)

Query: 25  NILFILIDDLR----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N++F++ DDL        +K V  PNI+ L   G  F NA  Q  +C PSR+S ++G RP
Sbjct: 32  NVIFMVSDDLNCYLGAYGNKDVISPNIDKLAARGTVFTNAACQFPVCGPSRSSFMSGLRP 91

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTD-DYPYSW 139
           ++  +    S        Q    TIP +FK HGY T   GKVF+   ++  TD D+    
Sbjct: 92  NTTGI---ISNGPSLYKTQPGVKTIPSYFKNHGYVTARAGKVFNHIDNNEKTDWDFILDG 148

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKL-ERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK- 197
              P         +A+   N   + L +   I   ++ R P     DL      +   K 
Sbjct: 149 GTSP---------EARKRANTGNEVLVDAGHIHWNAMWRDPECRDEDLADGANTLSVSKW 199

Query: 198 -KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDV 256
            K+   KPFFLA+GF KPH PL  PK+Y +     K++        + +P  + +  T  
Sbjct: 200 IKKKKDKPFFLAMGFLKPHRPLIVPKKYYELYDPKKLYHSWSRYANEVIPATAKN--TAG 257

Query: 257 RKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIV 312
            K ++            +  +  + +  +YYA   Y+D  +G L+  +D     + TI+V
Sbjct: 258 SKLEE-----------AITAEQRMGLNHAYYATVSYVDAQVGKLMQALDDAGLKENTIVV 306

Query: 313 LTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP--KLIPTVVHEPVELIDIFPTLVDLT 370
           L  D+G  LGE+  W K   F+ + +VPLI   P  K + +   + VELID+FPTL+++ 
Sbjct: 307 LFGDNGTHLGEHLCWGKNMLFEASARVPLIIADPANKTVKS-YDKVVELIDLFPTLIEMC 365

Query: 371 KL 372
           +L
Sbjct: 366 EL 367


>UniRef50_A0LK86 Cluster: Sulfatase precursor; n=1; Syntrophobacter
           fumaroxidans MPOB|Rep: Sulfatase precursor -
           Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
          Length = 487

 Score =  128 bits (308), Expect = 5e-28
 Identities = 103/363 (28%), Positives = 167/363 (46%), Gaps = 39/363 (10%)

Query: 25  NILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N+L  ++DD+            V  PNI+ L + G  F NA     +C+PSR S  TG R
Sbjct: 49  NVLMFVLDDMNDWIGCLGGHPDVKTPNIDRLAQRGVLFRNAQCSSPICSPSRASFFTGIR 108

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGK--SSNFTDDYPY 137
           P +  +Y     +R       N  T+PQ F  HGY +   GK+FH  K  S ++ + +P 
Sbjct: 109 PSTSGIYGNSQAFR---KIMPNAVTLPQHFIAHGYRSMGCGKLFHFIKTDSRSWHEFFPS 165

Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
              E P+ P   +  +A +       + +     P+ +     + L D +   +A D L+
Sbjct: 166 RSMERPFDP---VPPNAPLSGLPDVNQFDWG---PIDI---VDEELGDGKLARWAADALR 216

Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPK-EPNIPKDMPLVSWHPWTDV 256
           +R   +PFFL +G  +PH+PL  P++Y    P   +  P  + N   D+P  +   W   
Sbjct: 217 RRY-DRPFFLGVGLLRPHVPLYVPRKYFDMYPPESITLPTVKANDLDDVP-PTGVSWAKP 274

Query: 257 RKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIV 312
            +   I          V   +W  K    Y A+  ++D  +G +L  +D    +  T++V
Sbjct: 275 ERHQLI----------VEHDQWR-KAVAGYLASVSFVDAQVGWVLDALDESPYVNNTVVV 323

Query: 313 LTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVHEPVELIDIFPTLVDLT 370
           L  D+GW LGE   W K + ++ + +VPLI   P L P      +PV  +D++PTL +L 
Sbjct: 324 LWGDNGWHLGEKLHWTKLTLWEESCRVPLIIALPGLTPPGRKCAKPVSTMDVYPTLNELC 383

Query: 371 KLS 373
            L+
Sbjct: 384 DLT 386


>UniRef50_Q7UXP2 Cluster: Iduronate sulfatase; n=1; Pirellula
           sp.|Rep: Iduronate sulfatase - Rhodopirellula baltica
          Length = 456

 Score =  125 bits (302), Expect = 2e-27
 Identities = 105/381 (27%), Positives = 167/381 (43%), Gaps = 44/381 (11%)

Query: 4   VVNIILLNGDRVLTSDVETPK---NILFILIDDLRHL-----SDKKVYLPNINFLGKTGA 55
           V+ I+LL+    + +    PK   N+L + +DDL H       + +   PN + L K G 
Sbjct: 9   VLCIVLLSFQTYVPAAETVPKKQPNVLMVAVDDLNHWLTFMGRNPQAQTPNFDRLAKMGV 68

Query: 56  TFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRD-RSNGQGNFTTIPQFFKEHGY 114
            F NA+     C PSR +L+ GRRP +   Y     W+  +  G G    +   F   GY
Sbjct: 69  AFTNAYCAVPACEPSRCALMGGRRPWTTGCYKNGDQWKKYQPAGDG----MAAQFMNAGY 124

Query: 115 DTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVS 174
           + +  GK++H        D +P  W+ Y       M K          +K++      + 
Sbjct: 125 NVFGAGKIYHS------MDFHPSEWTNY-------MSKKGFSSNGPGVQKMDGYHNDKIH 171

Query: 175 VKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVH 234
              +  + L D  + DY I+ L   +  +PFF+A G +KPH+P   P++Y +  P+  + 
Sbjct: 172 PDLK-DEDLIDWHTTDYCIERLNSES-DQPFFIACGLYKPHLPFVAPRKYYEAFPLESIQ 229

Query: 235 RPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYID 294
            P  P+   D+  +   P   VR              G    +W   I QSY A   Y D
Sbjct: 230 LP--PHRENDLDDL---PPAGVRMAGADGDHKKFLKSG----RWKAAI-QSYLATCAYTD 279

Query: 295 ELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP 350
             +G LL   +       TI+VL +DHGWSLGE   W K++ ++   + P+I+  P +  
Sbjct: 280 MNLGRLLDAYENSPQKDNTILVLWTDHGWSLGEKQHWRKFALWEEPTRTPMIWVVPGMTT 339

Query: 351 --TVVHEPVELIDIFPTLVDL 369
                   V+L+ ++PTL  L
Sbjct: 340 PGARCERTVDLMSVYPTLCKL 360


>UniRef50_A6DIH4 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate-2-sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 621

 Score =  125 bits (301), Expect = 3e-27
 Identities = 117/425 (27%), Positives = 184/425 (43%), Gaps = 50/425 (11%)

Query: 4   VVNIILLNGDRVLTSDVETPK-NILFILIDDLRHL----SDKKVYLPNINFLGKTGATFN 58
           + +I L+   + +    +  K N+L I+ DDL H      D +   PN++        FN
Sbjct: 135 IADIKLVTAPQKMAIKAQNKKLNVLMIVSDDLNHYIKSYGDPQAITPNLDKFMAMSTQFN 194

Query: 59  NAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYS 118
            A+ Q  +C PSR S L+G  P+S  +     Y RD +    N     + F+ +GY T +
Sbjct: 195 KAYCQYPVCGPSRASFLSGLYPESSLVITNTQYLRDVNPSADNML---EHFRNNGYWTGA 251

Query: 119 VGKVFHP--GKSSNFTDDYPYSWSEYPYHPPTEMYK----------DAKVCRNKKTKKLE 166
            GK+FH   G     T    Y       +P   + K          D K   NK   K +
Sbjct: 252 AGKIFHSTYGMMEKGTSLDEYEKFSNAENPQLLLLKKRWIKEGKPGDFKAYFNKNKVKDQ 311

Query: 167 RNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRN-GSKPFFLAIGFHKPHIPLKFPKEYL 225
            +L+     + +  Q   D ++      ++K  + G KPFF+A G  KPH P   PK+YL
Sbjct: 312 ADLVLGYGTELRDNQH-GDGRNARRVAQWIKNNSAGEKPFFMACGIVKPHTPFYAPKKYL 370

Query: 226 KQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLN-ITFPFGVMPTKWTLKIRQ 284
                     PK+  I  D+P    + W +  K   ++R        GV   +      Q
Sbjct: 371 DLY-------PKDKLIFDDVP---ENDWDNKPKVAGVKRYQAFRGELGVNDRENRKYYLQ 420

Query: 285 SYYAAALYIDELIGILLSYV----DMQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVP 340
           SY     ++D  + +L+  +     M  T+IV  SDHG+ +GE+ ++ K + F+   +VP
Sbjct: 421 SYLGCISFMDAQVKVLMDALKESGQMDNTVIVFMSDHGFQIGEHFMYGKVTLFEECARVP 480

Query: 341 --LIFKSPKLIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPF 398
             +I+              ELID++PTL+DL KL        +HK       +GKSLVP 
Sbjct: 481 FGIIYPGNPGAGKQSDSLAELIDVYPTLLDLCKLPQP-----SHK------LQGKSLVPV 529

Query: 399 IENNS 403
            ++ S
Sbjct: 530 TKDTS 534


>UniRef50_A6DGD8 Cluster: Iduronate-sulfatase and sulfatase 1; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Iduronate-sulfatase
           and sulfatase 1 - Lentisphaera araneosa HTCC2155
          Length = 601

 Score =  125 bits (301), Expect = 3e-27
 Identities = 145/525 (27%), Positives = 236/525 (44%), Gaps = 83/525 (15%)

Query: 21  ETPKNILFILIDDLRHLS-----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLL 75
           E   N+LFI++DDL  L         +  P+++ L K G +F NA     +CAPSR+S+L
Sbjct: 18  EQKPNLLFIIMDDLNDLPIGSPLGNSIKTPHMDRLAKRGVSFTNAHTNDPICAPSRSSML 77

Query: 76  TGRRPDSLRLYDFYSYWRDR--------------SNGQGNFTT-------IPQ-FFKEHG 113
            G  P +  ++ F    +DR              +N    F T        PQ  FK +G
Sbjct: 78  YGLYPQTSGMFWFEKI-KDRKVLRESVDFPAHLKNNNYDVFGTGKIYHGGAPQKSFKSYG 136

Query: 114 YDT----YSV-GKVF---HPGKSSNFTD--DYPYSWSEYPYHPPTEMYKDAKVCRNKKTK 163
             T    + V G  F   HP +   F    D  Y W E  + P  ++   + +   KK  
Sbjct: 137 IRTNFGPHPVNGDPFMAHHPKQDYLFEKFPDLGYKW-EQTFGPLEDVPDWSHLPNGKKGW 195

Query: 164 KLERNLICPVSVKRQPGQSL-PDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPK 222
            L +    P S+K    + L PD  S ++    L +++  K F L  G  + H PL  PK
Sbjct: 196 FLGKT---PWSLKEGHNRDLLPDEISAEFCKKILAQKH-EKNFALLAGLVRTHTPLYAPK 251

Query: 223 EYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKI 282
           EY  + P+  +       +P+++ +  + P      R   +R         +  KW    
Sbjct: 252 EYFDRFPLDSIV------VPENIAIDQFAPSIADTSRYGFQRYQFLMQEKDLLKKWI--- 302

Query: 283 RQSYYAAALYIDELIGILLSYVDMQK----TIIVLTSDHGWSLGENGLWAKYSNFDYALK 338
            Q+Y A   ++D+ IG +L  +D  +    TI++LTSDHG+ +G+     K S +D A +
Sbjct: 303 -QAYLACVAFVDDQIGSILDALDKSEYADNTIVILTSDHGFHMGDKQFIYKQSLWDGATR 361

Query: 339 VPLIFKSPKLI--PTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLV 396
           VPLI    K +       +PV LIDI+PT++D  KLS    +    K T+QL  +G SL 
Sbjct: 362 VPLIISGLKGMAQDKKCTQPVSLIDIYPTIIDTLKLSKNPNRA---KSTAQL--DGHSLK 416

Query: 397 PFIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIM-GYSIRTKRYRYTEWISXXX 455
           P +++     +  +++     S  P K+    R+ +  +   +S+R++ +RYT  +S   
Sbjct: 417 PLLQDPQGDWQGPSVA----ISALPGKDHSMKRVYEGAMRPHFSVRSEDFRYT--LSSAG 470

Query: 456 XXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVLSIRL 500
                        EL+ +  DP+E++NL   ++YK I   L  +L
Sbjct: 471 EE-----------ELFHYKKDPLETQNLSEQAEYKEIKAQLKKQL 504


>UniRef50_Q7UQN9 Cluster: Choline sulfatase; n=3;
           Planctomycetaceae|Rep: Choline sulfatase -
           Rhodopirellula baltica
          Length = 502

 Score =  123 bits (297), Expect = 1e-26
 Identities = 100/365 (27%), Positives = 159/365 (43%), Gaps = 30/365 (8%)

Query: 19  DVETPKNILFILIDDLRHLSDK-----KVYLPNINFLGKTGATFNNAFAQQALCAPSRNS 73
           D  +  N+L I IDDL    +      +V  P +  L + G TF NA  Q  LC  SR S
Sbjct: 24  DSSSRPNVLMICIDDLNDWVEPLGGHPQVQTPAMKALAERGMTFANAHCQSPLCNSSRTS 83

Query: 74  LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTD 133
           L+   RP +  +Y    ++RD    +     +PQ FK HGY TYS GKV+H     + T+
Sbjct: 84  LMLSLRPSTTGIYGLAPWFRDLPELKDR-VALPQHFKAHGYRTYSAGKVYHGRYGRDKTE 142

Query: 134 -DYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYA 192
            D           PP ++     V  +          +    V     +   D +  D+ 
Sbjct: 143 FDEIGPPGVAGVKPPQKLIPSTPVGDHP---------LMDWGVFDHRDEDKGDYKVADWV 193

Query: 193 IDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPK-DMPLVSWH 251
            + L+     +PFF++ GF  PH+P     ++ +      +  P   +  + D    SW+
Sbjct: 194 TEKLEAMPEDEPFFMSCGFFLPHVPCHVTPKWWELYDDETLQLPPYRSDDRLDCSPFSWY 253

Query: 252 PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQ 307
              ++ +     R++      +        +  SY A   ++D  +G +L+ ++      
Sbjct: 254 LHWELPE----PRMS-----WLEAHNQQRNLVHSYLACISFVDSQVGRVLAALEGTPHRD 304

Query: 308 KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIFPTLV 367
            TII L SDHGW LGE  +  K + ++ +  VPLIF  P ++      P EL+DI+PTL 
Sbjct: 305 NTIICLWSDHGWHLGEKNVTGKNTLWERSTHVPLIFAGPGIVHGRTQSPAELLDIYPTLS 364

Query: 368 DLTKL 372
           DL  L
Sbjct: 365 DLVGL 369


>UniRef50_A6DSG8 Cluster: Iduronate sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 490

 Score =  123 bits (297), Expect = 1e-26
 Identities = 102/378 (26%), Positives = 163/378 (43%), Gaps = 45/378 (11%)

Query: 25  NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N++F  +DD+      +  K    PN++ L K G TF NA      CAPSR ++ TGR  
Sbjct: 21  NVIFFAVDDMNDWIGPMGSKMAKTPNMDRLAKMGVTFTNAHTSGVYCAPSRTAIFTGRNA 80

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH-------PGKSSNF-- 131
            +   Y    Y+ +  +    +  +   F + GY+TY VGK+FH       P   + F  
Sbjct: 81  TTSGCYTDQIYFHNHPD----YIPLHMAFNKGGYNTYGVGKLFHHPTGHIDPRGWTEFHL 136

Query: 132 --TDDYPYSW--SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQ 187
              D     W    + Y  P      A        K   R  +   ++       + D  
Sbjct: 137 RTEDQRKNGWPVETWGYEAPMPAQVPASKFNQVDKKWKGRPFMEVGAIPNDKEDEIVDTL 196

Query: 188 SLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKV-HRPKEPNIPKDMP 246
              +A D + K++  KPFF+A+G + PH P   P+ +    P+  + H P +     D+P
Sbjct: 197 RTKWACDIISKKH-DKPFFMALGLYAPHFPNYAPQRFFDMYPLESIKHGPWKEGDLDDIP 255

Query: 247 LVSWHPWTDVRKRDDIRRLNI---TFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSY 303
                     RK+   R+  I       G++ +  T+   Q Y A+  Y D  +G +L  
Sbjct: 256 -------QPERKKKLARKKGIHDKLIELGIVES--TI---QGYLASISYADSNLGRVLDA 303

Query: 304 VD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLI--PTVVHEPV 357
           ++       TIIV  SDHG++ GE G W K++ +     VP I+  P +    T  +  V
Sbjct: 304 LENSPNKDNTIIVFWSDHGYAQGEKGNWGKHTMWQRTTNVPFIWAGPGIAKGKTTSYTSV 363

Query: 358 ELIDIFPTLVDLTKLSDE 375
            LID++PTL DL  ++ +
Sbjct: 364 -LIDMYPTLTDLCGITPD 380


>UniRef50_Q7ULE7 Cluster: Iduronate-sulfatase and sulfatase 1; n=1;
           Pirellula sp.|Rep: Iduronate-sulfatase and sulfatase 1 -
           Rhodopirellula baltica
          Length = 1049

 Score =  123 bits (296), Expect = 1e-26
 Identities = 106/387 (27%), Positives = 164/387 (42%), Gaps = 38/387 (9%)

Query: 8   ILLNGDRVLTSDVETPK--NILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNA 60
           ILL           TP   N+LFI +DDL           +   PN++ L  +G  F NA
Sbjct: 13  ILLAAPSTFADSPPTPSGPNVLFIAMDDLNDWIGCLGGHPQTITPNLDRLAASGILFTNA 72

Query: 61  FAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVG 120
                 C P R+++ TGR P+   LYD     R+      +   +PQ+ + HGY     G
Sbjct: 73  HCPAPACNPCRSAVFTGRAPNQSGLYDNRQQMRE---VMPDDVILPQYMRNHGYHASGSG 129

Query: 121 KVFHPGKSSNFTDDY-PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQP 179
           K+ H    +   D+Y P + SE P+  P   Y   +    K+    +       ++    
Sbjct: 130 KLLHYFIDAASWDEYFPKAESENPF--PQTFYPSQRPVNLKRGGPWQYVETDWAALDVTD 187

Query: 180 GQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEP 239
            +   D     +  + L++++  +PFFL  G ++PH P   PK+Y +  P+  +  P   
Sbjct: 188 EEFGGDWAVSQWIGEQLQQKH-DQPFFLGCGIYRPHEPWFVPKKYFEPFPLDSIQLP--- 243

Query: 240 NIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGI 299
                 P    +   DV         N  F       +W   I Q Y A+  + D ++G 
Sbjct: 244 ------PGYLENDLDDVPPIGQRAARNRYFAHIQKQDQWKQGI-QGYLASIHFADAMLGR 296

Query: 300 LLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKL------- 348
           LL  ++       TI+VL SDHGW LGE   W KY+ +    +VPL+ + PK        
Sbjct: 297 LLDALESGPNADNTIVVLWSDHGWQLGEKEHWQKYTPWRGVTRVPLMIRVPKTSSPSLPN 356

Query: 349 ---IPTVVHEPVELIDIFPTLVDLTKL 372
              I      PV L+ +FPT++DL +L
Sbjct: 357 GTPIGARCDAPVNLLSLFPTVLDLCQL 383



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 61/245 (24%), Positives = 98/245 (40%), Gaps = 36/245 (14%)

Query: 12  GDRVLTSDVETPK-NILFILIDDL--RHLSDKK----VYLPNINFLGKTGATFNNAFAQQ 64
           GDR   + +   K N++ IL DD     LS +     +  P+I+ L   G    NA+   
Sbjct: 569 GDRTAQAVIPASKPNVVVILTDDQGWADLSCQNEVDDIQTPHIDGLAARGVRCTNAYVTA 628

Query: 65  ALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH 124
             C+PSR  L+TGR    L +               N  TI +  +  GY T  VGK +H
Sbjct: 629 PQCSPSRAGLITGRYQQRLGIDTIPDMPLPT-----NAVTIAEHLQPKGYKTGFVGK-WH 682

Query: 125 ---------------PGKSSNFTDDYPYSWSEY-PYHPP----TEMYKDAKVCRNKKTKK 164
                          P  +          W++  PY P      E Y   +         
Sbjct: 683 LEPNVTCIDWMRRELPAMAGKPRRKVRIPWNKIEPYSPSQQGFDEYYWGERTNYRTNFDL 742

Query: 165 LERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEY 224
               L+  +   R     + D+Q+ + A+ F+ +RN  +PF+L + ++ PH PL+  ++Y
Sbjct: 743 TSGELLAEMKPIRDERFRI-DVQT-NAAVKFI-QRNHDQPFYLQLNYYGPHTPLEATQKY 799

Query: 225 LKQMP 229
           L + P
Sbjct: 800 LDRFP 804


>UniRef50_UPI0000D9F62E Cluster: PREDICTED: similar to Iduronate
           2-sulfatase precursor (Alpha-L-iduronate sulfate
           sulfatase) (Idursulfase); n=1; Macaca mulatta|Rep:
           PREDICTED: similar to Iduronate 2-sulfatase precursor
           (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) -
           Macaca mulatta
          Length = 253

 Score =  122 bits (294), Expect = 2e-26
 Identities = 65/127 (51%), Positives = 78/127 (61%), Gaps = 5/127 (3%)

Query: 13  DRVLTSDVETPKNILFILIDDLRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRN 72
           D V+         I+  L D      D+ V  PN + L   G  F NAFAQQA+CAPSR 
Sbjct: 98  DAVVVPQPSLMAEIIIPLPDKGVACRDELVKAPNTDQLASQGLLFQNAFAQQAVCAPSRV 157

Query: 73  SLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFT 132
           S LTGRRPD+ RLYDF SYWR  +   GNF+TIPQ+FKE+GY T SVGKVFHPG +    
Sbjct: 158 SFLTGRRPDTTRLYDFNSYWRVHA---GNFSTIPQYFKENGYVTMSVGKVFHPGTAP--C 212

Query: 133 DDYPYSW 139
            +  +SW
Sbjct: 213 SESGFSW 219


>UniRef50_A5AB40 Cluster: Catalytic activity: choline sulfate + H2O
           = choline + sulfate; n=15; cellular organisms|Rep:
           Catalytic activity: choline sulfate + H2O = choline +
           sulfate - Aspergillus niger
          Length = 519

 Score =  119 bits (286), Expect = 2e-25
 Identities = 104/369 (28%), Positives = 160/369 (43%), Gaps = 44/369 (11%)

Query: 21  ETPKNILFILIDDLR------HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSL 74
           E   NIL+I+ D +       H  D  +  PN+N L + G  F++A+    LCAPSR  +
Sbjct: 3   EKKPNILYIMADQMAAPLLAFHDKDSPIKTPNLNKLAQEGVVFDSAYCNSPLCAPSRFVM 62

Query: 75  LTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSS----- 129
           +TG+ P  +  YD      + S+   +  T   + +  GY T   GK+   G        
Sbjct: 63  VTGQLPSKIGAYD------NASDLPADTPTYAHYLRREGYHTALAGKMHFCGPDQLHGYE 116

Query: 130 -NFTDD-YP--YSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPD 185
              T D YP  Y WS     P  E+  D     +  +  +E   +  V   +        
Sbjct: 117 QRLTSDIYPGDYGWSVNWDEP--EIRPD---WYHNMSSVMEAGPV--VRTNQLDFDEEVI 169

Query: 186 LQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDM 245
            +S  Y  + +++RN  +PF L +    PH P    KE+        +  PK+  IP D 
Sbjct: 170 YKSTQYLYNHVRQRN-DQPFCLTVSMTHPHDPYAMTKEFWDLYEDVDIPLPKQAAIPHDQ 228

Query: 246 PLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD 305
                    D   +  ++ +++      MP +     R++YYAA  Y+D  +G LL  +D
Sbjct: 229 Q--------DPHSQRVLKCIDLWGK--EMPEERIKAARRAYYAACTYVDTNVGKLLKVLD 278

Query: 306 ----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPK-LIPTVVHEPVELI 360
                  TIIV T DHG  LGE GLW K   ++ + +VP I  +PK   P  V E V  +
Sbjct: 279 DCGVRDDTIIVFTGDHGDMLGERGLWYKMVWYENSSRVPFIVHAPKRFAPKRVKENVSTM 338

Query: 361 DIFPTLVDL 369
           D+ PT  ++
Sbjct: 339 DLLPTFAEM 347


>UniRef50_A3ZT15 Cluster: Iduronate-2-sulfatase; n=1;
           Blastopirellula marina DSM 3645|Rep:
           Iduronate-2-sulfatase - Blastopirellula marina DSM 3645
          Length = 489

 Score =  116 bits (280), Expect = 1e-24
 Identities = 109/385 (28%), Positives = 175/385 (45%), Gaps = 41/385 (10%)

Query: 15  VLTSDVETPK--NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCA 68
           V TS V   K  N+L I +DDLR          V  P ++ L   G  F   + Q   C 
Sbjct: 16  VATSVVAAEKQPNVLLIAVDDLRTELGCYGLPYVESPRLDQLAAQGMLFRRHYVQVPTCG 75

Query: 69  PSRNSLLTGRRPDSLRLYD---FYSYWRDRSNGQ-GNFTTIPQFFKEHGYDTYSVGKVFH 124
            SR +LLTGR P + R      FYS     S  Q     T+P+ F+ +GY T  +GK+ H
Sbjct: 76  ASRFALLTGRSPVNTRAMANTAFYSGRNKLSPQQLPGAQTMPELFRRNGYHTVCIGKISH 135

Query: 125 PGKSSNF--------TDDYPYSWSEY--PYHPPTE---MYKDAKVCRNKKTKKLERNLIC 171
                 F         D+ P +W E   PY P      ++   +   +++     ++L+ 
Sbjct: 136 TADGKVFGYDGKGDGRDEMPGAWDELATPYGPWKRGWGVFFGYEGGSHREDGTGRQDLLE 195

Query: 172 PVSVKRQPGQSLPDLQSLDYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPI 230
             + +    + LPD    + AI  L + ++  +PFFL +GF KPH+P    K+    +  
Sbjct: 196 FTATR---DEDLPDGMLANAAIKKLGELKDRDEPFFLGLGFIKPHLPFVATKQDWDAIAE 252

Query: 231 SKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAA 290
            +V     P  P+ +    W    +  + D       + P   +  +  L  ++ Y A  
Sbjct: 253 REV---APPTAPEKLNSEFWSGSGEFYRYD--APYEKSHP---LAKEDALTAKRGYLACV 304

Query: 291 LYIDELIGILLSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP 346
            Y+D  IG +L  VD     + TI+V+  DHGW LGE  +W K++ ++  ++  LI ++P
Sbjct: 305 RYVDRQIGKVLDEVDRLGLAENTIVVVWGDHGWHLGEYAMWGKHALYERTVRSTLIVRAP 364

Query: 347 KLI-PTVVHEP-VELIDIFPTLVDL 369
            +  P  V +  V+ ID++PTL+DL
Sbjct: 365 GVTKPGSVSDAIVDSIDLYPTLIDL 389


>UniRef50_A4GIA7 Cluster: Iduronate sulfatase; n=1; uncultured
           marine bacterium HF10_49E08|Rep: Iduronate sulfatase -
           uncultured marine bacterium HF10_49E08
          Length = 414

 Score =  113 bits (272), Expect = 1e-23
 Identities = 89/310 (28%), Positives = 144/310 (46%), Gaps = 49/310 (15%)

Query: 92  WRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH-----PGKSSNFTDDYPYSWSEYPYHP 146
           WR  S        + Q F++HGY     GK+FH     PG S N  D    +W EY   P
Sbjct: 23  WRHESKVLEKAVVMSQHFRDHGYWAAGGGKIFHTLQWTPGDSQNDPD----AWDEYRGDP 78

Query: 147 PTEMYKD------AKVCRNKKT--KKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK 198
              + KD       KV +NK    K+   N     +V  +  ++  D   +D+AI+ +++
Sbjct: 79  LDPISKDWPRPASTKVNQNKGFIGKRPLGNHYFGAAVIEEDDETHGDHLVVDWAIERMQQ 138

Query: 199 RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPK--EPNIPKDMP--LVSWHPWT 254
           +   KP FLA+G  +PHIP +  +++    PI K+  P+  + ++    P   ++WH W 
Sbjct: 139 KR-EKPLFLAVGLFRPHIPFEVSQKWFDLYPIEKIRLPEYLKEDLSDARPHGRMNWHKWV 197

Query: 255 DVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTI 310
              K                  +W   + + Y A+  Y+D  +G LL  +D       T+
Sbjct: 198 TENK------------------QWK-HLMRGYLASISYVDHQVGRLLDALDSSGLKDNTV 238

Query: 311 IVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVHEPVELIDIFPTLVD 368
           +VL +DHG+ +GE   W K++ +D   +VPL   +P L        +PV L D++PTL +
Sbjct: 239 VVLWTDHGFHIGEKENWEKFALWDQTTRVPLFIHAPGLSKDGAKTRQPVTLTDLYPTLCE 298

Query: 369 LTKLSDEIPK 378
           L +L   +PK
Sbjct: 299 LAEL--PVPK 306


>UniRef50_Q7WC54 Cluster: Putative sulfatase; n=3;
           Proteobacteria|Rep: Putative sulfatase - Bordetella
           parapertussis
          Length = 529

 Score =  113 bits (271), Expect = 1e-23
 Identities = 103/371 (27%), Positives = 162/371 (43%), Gaps = 49/371 (13%)

Query: 25  NILFILIDDL-----RHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N LF++ D L     R   +     PN++ L      F N +    LCAPSR ++LTGR 
Sbjct: 8   NFLFLMADQLTAFALRMYGNGVCRTPNLDRLAARSTRFANMYCNFPLCAPSRVAMLTGRL 67

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNF-------T 132
           P S+ +YD      + S       T        GY T   GK+   G   +        T
Sbjct: 68  PSSVGVYD------NASEFSAEVPTFLHHLALAGYSTILSGKMHFVGPEQHHGFQERLTT 121

Query: 133 DDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPD---LQSL 189
           D YP   S++ + P  +  ++  +     T    R++I     +R       D    + +
Sbjct: 122 DIYP---SDFGWTP--DWREEIPIA---PTGMNMRSVIEAGEYRRSMQIDYDDDVVYRGV 173

Query: 190 DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIP-KDMPLV 248
               D L + +  +PFFLA+    PH P    +E+L       +  P  P IP       
Sbjct: 174 QKIYD-LGRLHRDRPFFLAVSMTHPHNPYVSTREFLDLYRPEDIDMPAVPPIPFAQQDPH 232

Query: 249 SWHPWTDVRKRD-DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM- 306
           S   W   R+ + D+   ++               R +YYA   Y+D  +G +L  +   
Sbjct: 233 SQRLWYMFRQDEYDVSDAHVR------------AARHAYYAMVSYVDAQVGRMLDALQAM 280

Query: 307 ---QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP-KLIPTVVHEPVELIDI 362
              + T++V T+DHG  LGE GLW K+ +FD A+++PL+  +P +  P V HE   L+DI
Sbjct: 281 DLDESTVVVFTADHGDMLGERGLWYKWVHFDPAVRIPLLISAPGRTRPAVRHELASLVDI 340

Query: 363 FPTLVDLTKLS 373
           FPT+++L  +S
Sbjct: 341 FPTMLELAGVS 351


>UniRef50_UPI000051016C Cluster: COG3119: Arylsulfatase A and
           related enzymes; n=1; Brevibacterium linens BL2|Rep:
           COG3119: Arylsulfatase A and related enzymes -
           Brevibacterium linens BL2
          Length = 509

 Score =  112 bits (270), Expect = 2e-23
 Identities = 102/374 (27%), Positives = 168/374 (44%), Gaps = 43/374 (11%)

Query: 23  PKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTG 77
           P NI+ I  D      L    D     PN++ L   GA F+ A+    LC+PSR S++TG
Sbjct: 3   PPNIVVIQADQMAAQALGAYGDTAALTPNMDALAADGAVFDRAYCNTPLCSPSRASMMTG 62

Query: 78  RRPDSLRLYDFYSYWRDRSNGQGNFTTIPQF---FKEHGYDTYSVGKVFHPGKSSNFTDD 134
           R P  +   D         NG     ++P F    ++ GY T  +G++   G   +   +
Sbjct: 63  RMPSDIDCLD---------NGDDFAASVPTFAHRLRKLGYHTALIGRMHFIGPDQHHGFE 113

Query: 135 YPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERN--LICPVSVKRQPGQSLPD------L 186
              +   YP     +M  D +   ++K +       +    + K    Q   D      L
Sbjct: 114 ERLTTDVYP--ADLDMVPDWQRPLDQKLQWYHEADPVFTAGAAKANVQQDFDDEVIFRTL 171

Query: 187 QSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMP 246
           + L+  +   +     +PF +   F  PH P + P+E+  +     +  P  P +P    
Sbjct: 172 RHLNGRVRANQAAGEDQPFLMVTSFIHPHDPYEPPREHWDRFAEVDIPDPAHPEVPD--- 228

Query: 247 LVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGIL---LSY 303
            ++  P +  R R  +  L+   P     T+   + R++YYAA  YID+ IG +   L  
Sbjct: 229 -IAEDPHSH-RLRT-MSGLDKKEP----GTEDIRRARRAYYAAVSYIDDHIGKIRQRLRE 281

Query: 304 VDMQ-KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP--KLIPTVVHEPVELI 360
           ++++  T+I++TSDHG  LGE GLW K S ++ + +VP+I   P   + P     PV L+
Sbjct: 282 LELEDNTVIIVTSDHGDMLGEKGLWYKMSPYEQSSRVPIIINGPAEAVTPGRYANPVSLV 341

Query: 361 DIFPTLVDLTKLSD 374
           D+ PTL++L   SD
Sbjct: 342 DLMPTLLELAGTSD 355


>UniRef50_Q4WLI2 Cluster: Choline sulfatase, putative; n=7;
           Eurotiomycetidae|Rep: Choline sulfatase, putative -
           Aspergillus fumigatus (Sartorya fumigata)
          Length = 589

 Score =  111 bits (266), Expect = 6e-23
 Identities = 94/368 (25%), Positives = 157/368 (42%), Gaps = 32/368 (8%)

Query: 25  NILFILIDDLR------HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           NIL+I+ D +       H  +  +  PN++ L + G  F++A+    LCAPSR  ++TG+
Sbjct: 7   NILYIMADQMAAPLLAFHDKNSPIKTPNLDRLAREGVVFDSAYCNSPLCAPSRFVMVTGQ 66

Query: 79  RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
            P  +  YD      + S+   +  T   + +  GY T   GK+   G       +   +
Sbjct: 67  LPSKIGAYD------NASDLPADIPTYAHYLRREGYHTALAGKMHFCGPDQLHGYEQRLT 120

Query: 139 WSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDL--QSLDYAIDFL 196
              YP      +  D    R      +   +     V+        ++  +S  Y  D +
Sbjct: 121 SDIYPGDYGWSVNWDEPDIRPDWYHNMSSVMEAGPVVRTNQLDFDEEVIYKSTQYLYDHV 180

Query: 197 KKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDV 256
           + R   +PF L +    PH P    KE+        +  PK P IP+D          D 
Sbjct: 181 RHRT-DQPFCLTVSMTHPHDPYAMTKEFWDLYEDVDIPLPKTPAIPQDQQ--------DP 231

Query: 257 RKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIV 312
             +  ++ +++      +P +     R++YYAA  Y+D  +G LL  ++       TI+V
Sbjct: 232 HSQRVLKCIDLWGK--EIPEERIKAARRAYYAACTYVDTNVGKLLKVLENCGLRDDTIVV 289

Query: 313 LTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP-KLIPTVVHEPVELIDIFPTLVDL-- 369
            T DHG  LGE GLW K   ++ + +VP+I  +P +  P  V E V  +D+ PT   +  
Sbjct: 290 FTGDHGDMLGERGLWYKMVWYENSARVPMIVHAPNRFAPKRVSENVSTMDLLPTFAAMAG 349

Query: 370 TKLSDEIP 377
             L  E+P
Sbjct: 350 APLVKELP 357


>UniRef50_A6RD60 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 614

 Score =  111 bits (266), Expect = 6e-23
 Identities = 96/369 (26%), Positives = 163/369 (44%), Gaps = 34/369 (9%)

Query: 25  NILFILIDD----LRHLSDKK--VYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           N+L+I+ D     L  L DK   +  PN++ L + G  F +A+    LCAPSR +++TG+
Sbjct: 8   NLLYIMADQMAAPLLSLYDKNSPIKTPNLDRLSREGVCFESAYCNSPLCAPSRFTMVTGQ 67

Query: 79  RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
            P  +  YD      + S+   +  T   + +  GY T   GK+   G       +   +
Sbjct: 68  LPSKIGGYD------NASDLSADTPTYAHYLRRQGYHTALAGKMHFAGPDQLHGYEQRLT 121

Query: 139 WSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDL--QSLDYAIDFL 196
              YP      +  D    R      +   +     V+        ++  +S  Y  D  
Sbjct: 122 SDIYPGDYGWTVNWDEPEVRPDWYHDMSSVMEAGPCVRTNQLDYDDEVIHKSTQYLYDHA 181

Query: 197 KKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDV 256
           + R   +PF L +    PH P    KEY        +  PK   +P D          D 
Sbjct: 182 RHRR-EQPFCLTVSMTHPHDPYAMTKEYWDLYEDVAIPLPKTSALPHDKQ--------DP 232

Query: 257 RKRDDIRRLNITFPFGV-MPTKWTLKIRQSYYAAALYIDELIGILLSYVDM----QKTII 311
             +  +R +++   FG  +P +  +  R++Y+AA  Y+D  +G L+  +       +TI+
Sbjct: 233 HSQRVLRCIDL---FGKEIPEERIVAARRAYFAACSYVDAQVGKLMETLKACDFADETIV 289

Query: 312 VLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP-KLIPTVVHEPVELIDIFPTLVDLT 370
           V T DHG  LGE GLW K   +++A +VP+   +P +  P  V E V  +D+ PT V +T
Sbjct: 290 VFTGDHGDMLGERGLWYKMVWYEHAARVPMFVHAPGRYKPKRVKENVSTMDLLPTFVAMT 349

Query: 371 --KLSDEIP 377
             ++++++P
Sbjct: 350 GGEMNNDLP 358


>UniRef50_A4U8Q3 Cluster: Sulfatase; n=2; Bacteria|Rep: Sulfatase -
           Aplysina aerophoba bacterial symbiont clone pAPKS18
          Length = 556

 Score =  109 bits (261), Expect = 2e-22
 Identities = 100/368 (27%), Positives = 161/368 (43%), Gaps = 48/368 (13%)

Query: 23  PKNILFILIDDL-----RHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTG 77
           P NIL +++D L     +         PN+  L   G  F NA+    +CAP+R SL++G
Sbjct: 57  PPNILLVMMDQLAPQVLKPYGGTVCRTPNLERLAGEGVVFENAYCNYPICAPARFSLMSG 116

Query: 78  RRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSS--NF---- 131
           R P  +  +D      + +       T   + +  GY T   GK+   G      F    
Sbjct: 117 RMPSRIGAFD------NATEFPSEVPTFAHYLRAMGYHTCLSGKMHFVGADQLHGFEDRV 170

Query: 132 -TDDYP--YSW-SEYPYHPP--TEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPD 185
            TD YP  +SW S++   P      +   ++ R+   ++   N     S   +       
Sbjct: 171 TTDVYPADFSWTSDWSLGPTFWEPWFHSVRIVRDAGPRRRSVN----TSYDEEA-----T 221

Query: 186 LQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDM 245
           +++  +  D   + +G +PFFLA  F  PH P   P  +        +  P+      D+
Sbjct: 222 VEACRWLHDHADRADG-RPFFLAASFISPHDPYLAPPSHWDLYTDDGIDDPRVG----DI 276

Query: 246 PLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD 305
           PL    P +        R +    P  V       + R++YYA   ++D+ IG +L  + 
Sbjct: 277 PLEERDPHSRRLYYTIGRHIETIGPADVR------RARRAYYAVMSWLDDRIGRILETLK 330

Query: 306 M----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLI-PTVVHEPVELI 360
                  TI+VLT+DHG  LGE GLW K + F+++++VPLI  +P L     V E V L+
Sbjct: 331 AIDADDNTIVVLTADHGDMLGERGLWLKMNFFEWSVRVPLIVHAPTLYRARRVRENVSLL 390

Query: 361 DIFPTLVD 368
           D+FPT ++
Sbjct: 391 DLFPTFLE 398


>UniRef50_A6DFB2 Cluster: Iduronate-sulfatase and sulfatase 1; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Iduronate-sulfatase
           and sulfatase 1 - Lentisphaera araneosa HTCC2155
          Length = 474

 Score =  108 bits (260), Expect = 3e-22
 Identities = 113/422 (26%), Positives = 177/422 (41%), Gaps = 64/422 (15%)

Query: 24  KNILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLL--- 75
           K+I+FI++DDL           +   PN++ L   G  F NA      C PSR S L   
Sbjct: 31  KDIVFIIVDDLNTWIGAMGGHPQTKTPNLDALATRGVLFTNAHCNAPQCGPSRKSFLTGL 90

Query: 76  ----TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEH----GYDTYSVGKVFHPGK 127
               TG+  +  +   F+     +     N    P  F  H     Y   S GKV H   
Sbjct: 91  YPKSTGKYFNVAKKMPFFKDQPLKGATSKNPPKKPLDFHTHFMKNNYRVVSGGKVDHGSL 150

Query: 128 SSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQ 187
            +   + +             +  K+ K   +K+      NL      +        D +
Sbjct: 151 KAKIDNKF-------------DRPKEVKHFTDKRV-----NLWGEGGPQNIDDTMTGDYK 192

Query: 188 SLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPK--DM 245
           +  +AI     ++  KP  +++GF++PH P   PKEY  + P+  +  PK P      D+
Sbjct: 193 TAQWAIKQWNTKS-DKPLLMSVGFYRPHRPFNVPKEYFDKFPLESIQLPKVPEFDDLADL 251

Query: 246 P-----LVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGIL 300
           P     L   +   ++ K   +   +I    G    +W   + QSY A   Y+D  IG+ 
Sbjct: 252 PEYGKALARSNAHKNLFKPRTVHE-HILHLGG--EDEWKYMV-QSYLACINYVDTQIGLF 307

Query: 301 LSYVDMQK----TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVH 354
           L  +        T+I+LTSDHGW LGE   W K + +    +VP I  +P L    TV  
Sbjct: 308 LETLKNNPRGNDTVIILTSDHGWDLGEKEHWCKAALWRTTTRVPYIVVAPGLTQAGTVNQ 367

Query: 355 EPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQC 414
           +P+  +DI+PTL D   ++   PK L          EG+S++P ++++S   EA  +S  
Sbjct: 368 QPISHVDIYPTLCDFAGIAK--PKHL----------EGQSILPLVKDSSAKREAAYLSYG 415

Query: 415 PR 416
           PR
Sbjct: 416 PR 417


>UniRef50_A6C1R0 Cluster: Choline sulfatase; n=1; Planctomyces maris
           DSM 8797|Rep: Choline sulfatase - Planctomyces maris DSM
           8797
          Length = 492

 Score =  105 bits (253), Expect = 2e-21
 Identities = 115/412 (27%), Positives = 190/412 (46%), Gaps = 64/412 (15%)

Query: 2   IYVVNIILLNGDRVLTSDVETPK--NILFILIDDLRH-----LSDKKVYLPNINFLGKTG 54
           + +++  L++  ++ T+  E P+  NILF+  DD R        +  +  PN++ L K G
Sbjct: 12  LLIISCSLISLSQISTA-AEKPERPNILFLFSDDQRADAVAAYDNPHIQTPNLDQLVKAG 70

Query: 55  ATFNNAFAQQ----ALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFK 110
             F NA+       A+C PSR  L +GR          Y    D         T+PQ  K
Sbjct: 71  FNFRNAYCMGSIHGAVCQPSRAMLNSGR--------SLYHVPMDLKG----VITLPQLLK 118

Query: 111 EHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKV-CRNKKTKKLERNL 169
           + GY+T+  GK +H     N  D +  S++         M    KV   + K  K E   
Sbjct: 119 QAGYETFGTGK-WH-----NHRDSFQKSFTTGTAAFIGGMSNHLKVPVVDLKEGKFEN-- 170

Query: 170 ICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMP 229
                  ++ G+       +D A+DFLK++   KPF+  + F  PH P + P E      
Sbjct: 171 -------KRTGKKFSSELFVDAAVDFLKQQPAEKPFYAYVAFTAPHDP-RMPPE-----T 217

Query: 230 ISKVHRPKEPNIPKDMPLVSWHPWTD--VRKRDDIRRLNITFPFGVMPTKWTLKIRQSYY 287
             KV+    P +PK+   +  HP+ +  +  RD+       +P      +  L     YY
Sbjct: 218 AMKVYENSPPPLPKNF--MPQHPFNNGWLTGRDEALT---GWPRQPEIVREQLA---EYY 269

Query: 288 AAALYIDELIGILLSYV---DMQK-TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIF 343
               ++D  IG +L  +   D+ K TI++ +SDHG +LG +GL  K + +++++K PLIF
Sbjct: 270 GMITHMDTQIGRILQTLKDKDLDKNTIVIFSSDHGLALGSHGLLGKQNLYEHSMKSPLIF 329

Query: 344 KSPKLIPTVVHEP-VELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKS 394
           K P +      +  V L DIFPT+ +LT++  ++P  +   D + + + GKS
Sbjct: 330 KGPGIPMNKSSDALVYLYDIFPTVCELTQI--QVPSGVEGSDLAPI-WRGKS 378


>UniRef50_A6DNH0 Cluster: Choline sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Choline sulfatase - Lentisphaera
           araneosa HTCC2155
          Length = 466

 Score =  104 bits (249), Expect = 6e-21
 Identities = 97/362 (26%), Positives = 161/362 (44%), Gaps = 43/362 (11%)

Query: 25  NILFILIDDLRHLSD-----KKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N+L I IDDL   +       +V  P+++ L  +G  F NA     +C+ SR S+++G  
Sbjct: 21  NVLMISIDDLNDWTGFLGGHPQVKTPHMDKLANSGRIFANAHCAVPVCSSSRVSVMSGLA 80

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
             +   Y+    ++       +  TI + FK  GY T + GKV H G   +  +D   S 
Sbjct: 81  ATTHGSYEIGPSYQSIP-ALKDVLTIQRHFKNQGYYTLAGGKVLHHGFKGSVANDNDRS- 138

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLP--DLQSLDYAIDFLK 197
                     + K     + K+   L           + PG      D++    A   L+
Sbjct: 139 ----------LIKGHSGPKPKQPLNLPEGWSRAWDWGQHPGTDAQAHDMKLAHNAAQALQ 188

Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLK---QMPISKVHRPKEP--NIPKDMPLVSWHP 252
           + +  KPFF+++GF +PH+PL  P ++     +  I     PK    ++PK+   ++ + 
Sbjct: 189 E-DFDKPFFMSVGFFRPHVPLLVPPKWFNLYDEESIVLAPSPKSDLDDVPKNFLSINDYA 247

Query: 253 WTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQK---- 308
                K              V+ T    K+  +Y A+  ++D  +G ++  +   K    
Sbjct: 248 VAPTHKE-------------VLATDSHRKLTHAYLASISFVDACVGRVIDALKNSKYADN 294

Query: 309 TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKL-IPTVVHEPVELIDIFPTLV 367
           TI++L SDHG+ LGE   WAK + ++ + KVPL+   P +       EP  LIDI+PTLV
Sbjct: 295 TIVILWSDHGFHLGEKEHWAKRTLWEESTKVPLLVYGPGIESGEACLEPASLIDIYPTLV 354

Query: 368 DL 369
           DL
Sbjct: 355 DL 356


>UniRef50_Q15XH4 Cluster: Sulfatase precursor; n=1;
           Pseudoalteromonas atlantica T6c|Rep: Sulfatase precursor
           - Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 517

 Score =  101 bits (241), Expect = 6e-20
 Identities = 103/381 (27%), Positives = 168/381 (44%), Gaps = 55/381 (14%)

Query: 25  NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           N+L ++ DD+R          V  PNI+ L   G  F+NA     LC+PSR +L TGR  
Sbjct: 36  NVLVLMFDDMRFDTFSYRGGPVPTPNIDALANDGTRFDNAMTTTGLCSPSRAALFTGRWG 95

Query: 81  DSLRLYD----FYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
               L D    ++S+  + S  +G    + +   + GY    VGK +H G          
Sbjct: 96  HKTGLDDNVGLYHSHVDELSEEEGG---VIRRAADTGYHVGYVGK-WHLGPQGPALRGAD 151

Query: 137 YSWSE--------YPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPG--QSLPDL 186
           + W +         PY P  +  K A+  R ++ +  E++       +  PG  ++    
Sbjct: 152 FMWGKEHSQARHSRPYVPYEKQAKMAQYNRGERDENGEKH----EYYQTLPGTYETSHTA 207

Query: 187 QSLDYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDM 245
           +++D     L++     +PFF  I F +PH P + P+ Y        V  P    + +  
Sbjct: 208 ENVDMGQKMLREAAKMDEPFFGVISFEQPHPPYRVPEPYASMFDPKTVKLPANHAVKRQF 267

Query: 246 -PLV---SWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIG-IL 300
            P+     W PW DV    D+               W  K R  YY A   ID  +G I+
Sbjct: 268 KPMAQDEDWWPWHDVGHMTDM--------------DWR-KSRTFYYGAIAMIDHAVGDII 312

Query: 301 LSYVDM----QKTIIVLTSDHGWSLGENGLWAK--YSNFDYALKVPLIFKSPKLIPTVVH 354
            +  D+      TIIVL  D G  LGE+ L+ K  Y+ +D  +++PLI ++P + P +V+
Sbjct: 313 KTAKDVGMYDDLTIIVL-GDQGSMLGEHNLYDKGPYA-YDELMRMPLIIRAPNVEPRIVN 370

Query: 355 EPVELIDIFPTLVDLTKLSDE 375
           + V ++DI PT+ ++  L  +
Sbjct: 371 KQVSMLDIAPTISEMMSLEPD 391


>UniRef50_A0GDT1 Cluster: Sulfatase; n=1; Burkholderia phytofirmans
           PsJN|Rep: Sulfatase - Burkholderia phytofirmans PsJN
          Length = 499

 Score =  101 bits (241), Expect = 6e-20
 Identities = 98/370 (26%), Positives = 164/370 (44%), Gaps = 41/370 (11%)

Query: 17  TSDVETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSR 71
           T +   P N+LFIL D+ +H          +  P+++ L + G  F NA+    +C P+R
Sbjct: 20  TDNAMKPTNVLFILSDEHQHNLMGCAGHPVIKTPSLDALAQRGTRFENAYTPSPICVPAR 79

Query: 72  NSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNF 131
            SL TGR    +R       W +     G+     Q     G  T S+GK+ +   +S  
Sbjct: 80  ASLATGRYVHDIRC------WDNAIAYDGSTPGWAQHLSASGVLTESIGKLHYKSDAS-- 131

Query: 132 TDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQS---LPDLQS 188
                +   ++  H    + +     RN   + + R+   P+  K  PG S     D++ 
Sbjct: 132 --PVGFRRQQHAVHILDGIGQVWGSVRNPMPETMGRS---PLYDKIGPGTSDYNRFDMRV 186

Query: 189 LDYAIDFLKKRNG-SKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPL 247
            D A  +L +     KP+ L +G   PH PL  P+++L       ++ P+E ++P   P 
Sbjct: 187 ADTACGWLGEHAADDKPWVLFVGLVAPHFPLVVPQDFL------DLYDPREIDLPLLHPS 240

Query: 248 VSW--HPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD 305
             +  HPW +       R ++     G    +  L +   YYA   ++D  +G +L+ + 
Sbjct: 241 TGYVRHPWVE----RQARHMDHDAAIG-SDERRRLAV-ACYYALVSFLDAQVGKVLAALR 294

Query: 306 M----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHE-PVELI 360
                  T I+ +SDHG +LG+ G+W K   +  +  VP+I   P +  + V E PV LI
Sbjct: 295 ASGLDDSTTIIYSSDHGDNLGKRGMWNKCLMYRESTGVPMIVAGPGIPASKVSETPVSLI 354

Query: 361 DIFPTLVDLT 370
           DI  TL++ T
Sbjct: 355 DIQNTLLECT 364


>UniRef50_Q46P27 Cluster: Sulfatase; n=2; Bacteria|Rep: Sulfatase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 482

 Score = 98.3 bits (234), Expect = 4e-19
 Identities = 83/334 (24%), Positives = 142/334 (42%), Gaps = 29/334 (8%)

Query: 42  VYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGN 101
           V  PN++ L   G  F++A+    +C P+R +  TGRR   +RL+D    +     G G+
Sbjct: 27  VKTPNLDALAARGVRFSSAYTPSPICVPARAAFATGRRVHQVRLWDNAMPYTGEQRGWGH 86

Query: 102 FTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNK- 160
                   ++ G    S+GK+ +     N  D   +     P H            RN  
Sbjct: 87  V------LQDRGIRVESIGKLHY----RNEEDPAGFDAEHLPMHVVGGHGMVWASIRNPF 136

Query: 161 KTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK--RNGSKPFFLAIGFHKPHIPL 218
           + ++    ++       +   +  D      A+ +L++  +     F L +G   PH P 
Sbjct: 137 RPRENGPRMLGEHIGPGESSYTQYDRAVTQRAVQWLQEAAQRQEAGFVLYVGLVAPHFPF 196

Query: 219 KFPKEYLKQMPISKVHRPK-EPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTK 277
             P+E+    P   +  PK  P    +      HPW  VR+  D       F        
Sbjct: 197 VVPEEFYSLYPTDGLPEPKLHPRTGYEQ-----HPW--VREYCDFMASERQFA----DAD 245

Query: 278 WTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNF 333
             L+   +YY    ++D  +G +L  +        T IV TSDHG +LG  G+W K + +
Sbjct: 246 ERLRAFAAYYGLCTWLDHNVGQILGALRDNGLEDTTHIVYTSDHGDNLGARGVWGKSTLY 305

Query: 334 DYALKVPLIFKSPKLIPTVVHEPVELIDIFPTLV 367
           + ++KVP++   P + P V + PV+L+D+FPT++
Sbjct: 306 EESVKVPMLLAGPIVTPGVCNTPVDLLDLFPTIL 339


>UniRef50_Q17CP8 Cluster: Sulfatase; n=2; Culicidae|Rep: Sulfatase -
           Aedes aegypti (Yellowfever mosquito)
          Length = 495

 Score = 97.5 bits (232), Expect = 7e-19
 Identities = 94/382 (24%), Positives = 159/382 (41%), Gaps = 40/382 (10%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDDLRH-LSDKKVYLPNINFLGKTGATFNN 59
           ++ +  II+L+   +     E   NI+ +L DD    L      +     +   GATF N
Sbjct: 4   LLRISPIIILSVLALAVQAEENAPNIVLVLTDDQDVVLKGLNPMVQTQQLIANRGATFMN 63

Query: 60  AFAQQALCAPSRNSLLTGRRPDSLRLYD-------FYSYWRDRSNGQGNFTTIPQFFKEH 112
           AF    +C PSR+SLLTG+   +++ ++       + ++WR++       +T P   +E 
Sbjct: 64  AFTSSPICCPSRSSLLTGQYAHNVKTFNNSQTGGCYGTHWREKVEP----STFPVLLQEA 119

Query: 113 GYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICP 172
           GY T+  GK      +  ++ + P  WS++        Y +  +  N +        +  
Sbjct: 120 GYRTFYAGKYL----NEYYSKEVPPGWSDWHGLHGNSKYYNYTLNENGQIVSFTEEYLTD 175

Query: 173 VSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISK 232
           V   R               +DFL K     PFF  +    PH P      +        
Sbjct: 176 VLSNR--------------TVDFLSKAEQGVPFFAMVAPPAPHAPYTAATRHEDTFADVN 221

Query: 233 VHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALY 292
             R K  N+P   PL   H W        +    +     +   +W     QS  A    
Sbjct: 222 APRTKNYNLPCG-PLEK-H-WLLTMPPSPLPADILASIDIIYRKRW-----QSLMAVDEM 273

Query: 293 IDELIGILLSYVDMQKTIIVLTSDHGWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIP- 350
           ++ ++  L     +  T I+ TSD+G+ +G+ GL + K   ++  ++VPL+   PK+ P 
Sbjct: 274 VESIVATLEKRNMLTDTYIIYTSDNGYHMGQFGLPYDKRQPYETDIRVPLLMTGPKIPPK 333

Query: 351 TVVHEPVELIDIFPTLVDLTKL 372
           T+V  PV LIDI PT+++L  L
Sbjct: 334 TLVSAPVVLIDIAPTVLELAGL 355


>UniRef50_A6C9S7 Cluster: Choline sulfatase; n=1; Planctomyces maris
           DSM 8797|Rep: Choline sulfatase - Planctomyces maris DSM
           8797
          Length = 549

 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 107/396 (27%), Positives = 182/396 (45%), Gaps = 77/396 (19%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDDLR----H-LSDKKVYLPNINFLGKTGA 55
           +++++   +L+ + ++ ++ + P N+LF+  DD R    H L +  +  P+++ L ++G 
Sbjct: 11  LLFILCFTVLSSNTLVAAEKQKP-NVLFLFTDDQRADTIHALGNPLIKTPHLDQLVQSGF 69

Query: 56  TFNNAFA----QQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKE 111
            FNNA+       A+C  SRN LL+GR          Y  W  R          P   K 
Sbjct: 70  VFNNAYCLGSNSGAVCVCSRNMLLSGRT---------YFRWTGRY-ASAEKPNFPDSMKA 119

Query: 112 HGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLIC 171
            GY TY      H GK  N   +          H   + +  +K   + + + L      
Sbjct: 120 AGYYTY------HHGKKGNTAAEI---------H---KRFDQSKYLNDTRARLLG----- 156

Query: 172 PVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPIS 231
                 QPG+ +     +D AI+FL+K+N ++PFF+ + F  PH P    +EY+      
Sbjct: 157 ------QPGKEI-----VDDAIEFLQKKN-TQPFFMYLAFACPHDPRVADQEYMD----- 199

Query: 232 KVHRPKEPNIPKDMPLVSWHPWTDVRK--RDDIRRLNITFPFGVMPTKWTLKIRQSYYAA 289
             H  +E  IP     +  HP+ +  +  RD+   L   FP      +   K    YYA 
Sbjct: 200 --HYERE-EIPLPANYLPLHPFNNGEQVVRDE---LLAGFPRSKAEIR---KHLHDYYAD 250

Query: 290 ALYIDELIGILLSYV----DMQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKS 345
              +D  IG L+  +    +   T+I+ +SDHG ++G +GL  K S +++++K PLIF  
Sbjct: 251 ITGLDRHIGRLIKALKESGEYDNTVIIFSSDHGLAVGSHGLMGKQSLYEHSMKSPLIFSG 310

Query: 346 PKLIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLN 381
           P +     +  V L DIFPT+ ++  +  +IP+ L+
Sbjct: 311 PGIPHGQSNALVYLYDIFPTVCEM--VGTDIPQGLD 344


>UniRef50_A6DGE4 Cluster: Iduronate-sulfatase and sulfatase 1; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Iduronate-sulfatase
           and sulfatase 1 - Lentisphaera araneosa HTCC2155
          Length = 566

 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 83/329 (25%), Positives = 150/329 (45%), Gaps = 46/329 (13%)

Query: 186 LQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDM 245
           LQ     +  ++++   +PFF+A+G+ +PH PL  P +Y    P+ KV  P       D+
Sbjct: 220 LQWFQKKLKSMEQQGHDEPFFMALGYIRPHTPLVVPDKYFDMFPLDKVKLPTRKQ--DDL 277

Query: 246 PLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLK-IRQSYYAAALYIDELIGILLSYV 304
              ++   +    R       I     +   +  L+   Q+Y A+  + D+++G  +  +
Sbjct: 278 EDTNYSSASGNSSR------GIKIYEALQTEEDALRRYTQAYLASIAFADDMLGQTIDAL 331

Query: 305 DMQK----TIIVLTSDHGWSLGE-NGLWAKYSNFDYALKVPLIFKSPKL---IPTVVHEP 356
           +       TI++L SDHG+ +GE N +W KY+ ++ + +VP + K PK      T+V  P
Sbjct: 332 EKSSFNDNTIVILFSDHGYHVGEKNNVW-KYTLWEDSTRVPFMIKHPKYKNNAGTIVSHP 390

Query: 357 VELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIEN-NSNGLEAFAISQCP 415
           + L+D+FPT+ D  +L+ +       K  S    +G S+  F+EN NS   +   ++   
Sbjct: 391 ISLVDVFPTIKDFCQLTGD-----TRKHASGAPLDGHSVKTFLENPNSTQWQGPDVAMTM 445

Query: 416 RPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHII 475
             S Y  K  +K  +        ++R+K +RY  + +                ELYDH  
Sbjct: 446 LDS-YTSKLPEKQNI--------AVRSKDFRYIRYANGEE-------------ELYDHRR 483

Query: 476 DPIESKNLFLVSKYKNIAKVLSIRLRSSV 504
           DP E  NL    +Y ++   L   ++  +
Sbjct: 484 DPHEWANLASNPEYASVKSQLQTSMKKEL 512



 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 44/125 (35%), Positives = 62/125 (49%), Gaps = 9/125 (7%)

Query: 16  LTSDVETPK-NILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNAFAQQALCAP 69
           L S  +T K N+L I+ DDL           +   PN   L      F NA +   +C+P
Sbjct: 13  LVSFAQTEKSNVLMIVFDDLNDFISPMGGHSQSTTPNFKALADDSVVFKNAHSNAPVCSP 72

Query: 70  SRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSS 129
           SR S +TG  P S R Y F + +   ++   N  T+PQ+ +E+ Y TYS GK+FH GK  
Sbjct: 73  SRASFMTGVHPYSSRNYGFKNAF--ANSVLKNSKTLPQYMQENNYKTYSAGKIFH-GKVK 129

Query: 130 NFTDD 134
              D+
Sbjct: 130 GVWDE 134


>UniRef50_A4AMS2 Cluster: Choline sulfatase; n=1; Flavobacteriales
           bacterium HTCC2170|Rep: Choline sulfatase -
           Flavobacteriales bacterium HTCC2170
          Length = 503

 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 106/380 (27%), Positives = 172/380 (45%), Gaps = 51/380 (13%)

Query: 25  NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQA----LCAPSRNSLL 75
           NI+ I  DD+ +     L +K++  PN++ L K G TF NA+   A    +C  SR  ++
Sbjct: 29  NIVLIFADDMTYTAINALGNKEIQTPNLDRLVKGGTTFKNAYNMGAWNGAVCVASRAMMI 88

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK--VFHPGKS--SNF 131
           +GR   +    +F   W +   G+    T  +  +  GYDTY  GK  V  P  S   N 
Sbjct: 89  SGRSVWNAN--NFRQNWLE---GKEFDKTWGKLMESAGYDTYMTGKWHVDAPADSVFQNV 143

Query: 132 TD---DYPY-SWSEYPYHPP-TEMYKDAKVCRNKKT----KKLERNLIC--PVSVKRQP- 179
           T      P+ SW      P   EM K+ K  +  +     + L  N     PV  K    
Sbjct: 144 THVRRGMPWDSWGHGGKIPAINEMIKEGKSKKEIRAIGYNRPLNENDTTWNPVDKKFGGF 203

Query: 180 ---GQSLPDLQSLDYAIDFLKKRN-GSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHR 235
              G+   ++   D A+ F+ +      PFF+ + F+ PH P + P+EY+    + K+  
Sbjct: 204 WVGGKHWSEVLK-DDAVGFIDQAKVKDNPFFMYLAFNAPHDPRQAPQEYVDMYSLDKISL 262

Query: 236 PKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKW-TLKIRQSYYAAALYID 294
           PK       MP+   +P+ D        R     PF    T++ T K  Q YYA   ++D
Sbjct: 263 PKSW-----MPM---YPYKDSIGNGPGLRDEALAPFP--RTEYATKKHIQEYYALISHMD 312

Query: 295 ELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP 350
             IG +L  ++    M+ T ++ T+DHG ++G++GL  K S FD++++ P +   P +  
Sbjct: 313 NQIGEILDALENSGKMENTYVIFTADHGLAIGKHGLLGKQSQFDHSIRPPFMIVGPDIPK 372

Query: 351 TV-VHEPVELIDIFPTLVDL 369
              + + + L D   T +DL
Sbjct: 373 DASIDKDIYLQDAMATSLDL 392


>UniRef50_O69787 Cluster: Choline-sulfatase; n=28;
           Alphaproteobacteria|Rep: Choline-sulfatase - Rhizobium
           meliloti (Sinorhizobium meliloti)
          Length = 512

 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 96/373 (25%), Positives = 155/373 (41%), Gaps = 46/373 (12%)

Query: 25  NILFILIDDL--RHLSDKK---VYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NIL I++D L  +   D     ++ PN+  L K  A F+N +    LCAP+R S + G+ 
Sbjct: 7   NILIIMVDQLNGKLFPDGPADFLHAPNLKALAKRSARFHNNYTSSPLCAPARASFMAGQL 66

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNF-----T 132
           P   R+YD      + +  Q +  T     +  GY T   GK+    P +   F     T
Sbjct: 67  PSRTRVYD------NAAEYQSSIPTYAHHLRRAGYYTALSGKMHFVGPDQLHGFEERLTT 120

Query: 133 DDYPYSWSEYP-YHPPTEM----YKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQ 187
           D YP  +   P Y  P E     Y +          ++   +     V     Q L    
Sbjct: 121 DIYPADFGWTPDYRKPGERIDWWYHNLGSVTGAGVAEITNQMEYDDEVAFLANQKL---- 176

Query: 188 SLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPL 247
              Y +         +P+ L + F  PH P    +++       +   P+   IP D   
Sbjct: 177 ---YQLSRENDDESRRPWCLTVSFTHPHDPYVARRKFWDLYEDCEHLTPEVGAIPLD--- 230

Query: 248 VSWHPWTD-VRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD- 305
               P +  +    D +  ++T        +   + R++Y+A   Y+DE +G L+  +  
Sbjct: 231 -EQDPHSQRIMLSCDYQNFDVT-------EENVRRSRRAYFANISYLDEKVGELIDTLTR 282

Query: 306 ---MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDI 362
              +  T+I+  SDHG  LGE GLW K + F+ + +VPL+   P + P +   P   +D+
Sbjct: 283 TRMLDDTLILFCSDHGDMLGERGLWFKMNFFEGSARVPLMIAGPGIAPGLHLTPTSNLDV 342

Query: 363 FPTLVDLTKLSDE 375
            PTL DL  +S E
Sbjct: 343 TPTLADLAGISLE 355


>UniRef50_Q62DH2 Cluster: Choline sulfatase; n=37; cellular
           organisms|Rep: Choline sulfatase - Burkholderia mallei
           (Pseudomonas mallei)
          Length = 517

 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 111/414 (26%), Positives = 184/414 (44%), Gaps = 68/414 (16%)

Query: 25  NILFILIDDL-----RHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NIL ++ D L     R    +    P I+ L   G  F+ A+    LCAPSR +L+ G+ 
Sbjct: 13  NILVLMADQLTPFALRAYGHRATRTPTIDRLAAEGVVFDAAYCASPLCAPSRFALMAGKL 72

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNF-----T 132
           P +L  YD      + +       T   + +  GY T   GK+    P +   F     T
Sbjct: 73  PSALGAYD------NAAELPAQTLTFAHYLRAAGYRTMLSGKMHFCGPDQLHGFEERLTT 126

Query: 133 DDYP--YSW-------SEYP--YHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQ 181
           D YP  + W       +E P  YH  + +  DA  C   +T +L+ +     + +++   
Sbjct: 127 DIYPADFGWVPDWTRPAERPSWYHNMSSVL-DAGPC--VRTNQLDFDDDATFAARQK--- 180

Query: 182 SLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNI 241
                   D A +    R+ ++PF + +    PH P    +EY        ++R ++ ++
Sbjct: 181 ------IFDVARERAAGRD-ARPFCMVVSLTHPHDPYAITREYWD------LYRDEDIDL 227

Query: 242 PK-DMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGIL 300
           P   M   +  P +  R+   +  ++ T P  +       + R++YY A  Y+D   G L
Sbjct: 228 PAVRMDFDASDPHS--RRLRAVCEVDRTPPEDLQ----IRRARRAYYGATSYVDAQFGAL 281

Query: 301 LSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTV-VHE 355
           L+ ++       TI+++T+DHG  LGE GLW K + F+ A +VPLI  +P+  P   V  
Sbjct: 282 LATLEQCGLADDTIVIVTADHGDMLGERGLWYKMTFFEGACRVPLIVHAPRRFPAARVPA 341

Query: 356 PVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAF 409
            V  +D+ PTLV+L   + E  +  +  D      +G+SLVP +       EAF
Sbjct: 342 AVSHVDLLPTLVELA--TGE--RRADWPD----AVDGRSLVPHLRGEGGHDEAF 387


>UniRef50_A3SJ21 Cluster: Sulfatase; n=1; Roseovarius nubinhibens
           ISM|Rep: Sulfatase - Roseovarius nubinhibens ISM
          Length = 518

 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 81/345 (23%), Positives = 149/345 (43%), Gaps = 35/345 (10%)

Query: 45  PNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTT 104
           P+++ L   G  F+ A+    LCAPSR + ++G+    +  YD  S +R          T
Sbjct: 38  PHMDALAARGMRFDAAYCNAPLCAPSRFAFMSGQLISRIAAYDNASEFR------ATVPT 91

Query: 105 IPQFFKEHGYDTYSVGKVFH--PGKSSNF-----TDDYPYSWSEYPYHPPTEMYKDAKVC 157
              +    GY T   GK+    P +   F     TD YP   S++ + P  E   D ++ 
Sbjct: 92  FAHYLSALGYRTCLSGKMHFVGPDQKHGFQDRVTTDIYP---SDFAWTPDWEA-PDERID 147

Query: 158 RNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSK--PFFLAIGFHKPH 215
           +     +  +   C ++  +       +  +  + ID  + R   +  P  +   F  PH
Sbjct: 148 KWYHNMQTVKESGCAIATFQTDYDDEVEFAARRWLIDRARDRAAGQEAPLCMVASFIHPH 207

Query: 216 IPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMP 275
            P      Y+ +     ++   E  +P+ +PL    P++  R  D I    +      + 
Sbjct: 208 DP------YVARPEWWDLYSDDEIELPEVLPLADHDPFSR-RLMDGIEASYVP-----LS 255

Query: 276 TKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYS 331
               ++ R++Y A   Y D  IG L+  +D    +  T++++T+DHG  LGE GLW K +
Sbjct: 256 RDEVIRARRAYLANVSYFDSKIGALVKTLDETGELDNTVVIVTADHGDMLGERGLWYKMN 315

Query: 332 NFDYALKVPLIFKSPKLIPTVVHEPVELIDIFPTLVDLTKLSDEI 376
            F+++ +VPLI   P ++         LID+ P+ +++    + +
Sbjct: 316 FFEHSARVPLIMAGPGVVQGAAANACSLIDLLPSFLEIAGADESV 360


>UniRef50_Q8XNV1 Cluster: Sulfatase; n=2; Clostridium
           perfringens|Rep: Sulfatase - Clostridium perfringens
          Length = 481

 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 107/379 (28%), Positives = 175/379 (46%), Gaps = 48/379 (12%)

Query: 25  NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NI+ I++D +R        ++ +  PN++ +   G  F NA+     C  SR S+LTG  
Sbjct: 4   NIVLIMVDQMRGDCLGVNGNEFIETPNLDMMATEGYNFENAYTAVPSCIASRASILTGM- 62

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVF-HPGKS----SNFT-- 132
             S + +    Y    S    N  TI   F + GY T  +GK+  +P ++     N    
Sbjct: 63  --SQKSHGRVGYEDGVSWNYEN--TIASEFSKAGYHTQCIGKMHVYPERNLCGFHNIMLH 118

Query: 133 DDYPYSWSEYPYHPPTEMYKD---AKVCRNKKTKKLER---NLICPVSVKRQPG--QSL- 183
           D Y +          T++ +     K  R KK   ++     L C   V R  G  ++L 
Sbjct: 119 DGYLHFARNKEGKASTQIEQCDDYLKWFREKKGHNVDLIDIGLDCNSWVSRPWGYEENLH 178

Query: 184 PDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPK 243
           P    ++ +IDFL++R+ SKPFFL + F +PH PL  PK Y            K+ ++P+
Sbjct: 179 PTNWVVNESIDFLRRRDPSKPFFLKMSFVRPHSPLDPPKFYFDMY--------KDEDLPE 230

Query: 244 DMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIG---IL 300
             PL+    W + ++ ++ R  +I    G++  K   + + +YY +  +ID  IG   I 
Sbjct: 231 --PLMG--DWAN-KEDEENRGKDINCVKGIINKKALKRAKAAYYGSITHIDHQIGRFLIA 285

Query: 301 LS-YVDMQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP-KLIP----TVVH 354
           LS Y  +  TI +  SDHG  +G++  + K   ++ + +VP     P  L+      V  
Sbjct: 286 LSEYGKLNNTIFLFVSDHGDMMGDHNWFRKGIPYEGSARVPFFIYDPGNLLKGKKGKVFD 345

Query: 355 EPVELIDIFPTLVDLTKLS 373
           E +EL DI PTL+D   +S
Sbjct: 346 EVLELRDIMPTLLDFAHIS 364


>UniRef50_A6DKC4 Cluster: Iduronate-sulfatase and sulfatase 1; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Iduronate-sulfatase
           and sulfatase 1 - Lentisphaera araneosa HTCC2155
          Length = 548

 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 92/350 (26%), Positives = 160/350 (45%), Gaps = 40/350 (11%)

Query: 167 RNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGS--KPFFLAIGFHKPHIPLKFPKEY 224
           +N+        + G   PD  + D    +L+ +      PF+L +GF +PH P+   +++
Sbjct: 212 KNINAKTEYDPKRGYMTPDKVNADLVKGWLEGKGDELKAPFYLNLGFVRPHTPMHAEQKH 271

Query: 225 LKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDD-IRRLNITFP-FGVMPTKWTLKI 282
               PI  V    +  + +   +  + P  D  K +   ++++  +  +G + T + L  
Sbjct: 272 FDHFPIEDV----QLTVGQLETIKHFKPLDDYSKLEKPYKKVHELYASYGDLTTAFKL-Y 326

Query: 283 RQSYYAAALYIDELIGILLSYVDMQK----TIIVLTSDHGWSLGENGLWAKYSNFDYALK 338
            Q+Y A+    DE IG +L  ++  K    TI+++TSDHGW  GE+    K S ++ + +
Sbjct: 327 NQAYLASVHAADENIGRVLDALEKSKYKDNTIVIITSDHGWHNGEHFQIGKNSTWEESCR 386

Query: 339 VPLIFKSPKLIP--TVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLV 396
           +PL+ + P L         PV LIDI+PTLVDL KL  +  K    K    L   G SL 
Sbjct: 387 IPLLIRVPDLAKAGAKCEVPVSLIDIYPTLVDLCKLKGKTAK----KGGPSL--SGHSLK 440

Query: 397 PFIENNSNGL---EAFAISQCPRPSVYPQKNSDKPRLKDIT--IMGYSIRTKRYRYTEWI 451
           P + N        +  A++   +   +  K      ++DI    + YS+R+K+YR+  ++
Sbjct: 441 PLLVNPEKAEWTGDDIAVTAIMK-QWFSDKQQQTMSVEDIVEKSLKYSMRSKQYRFV-YV 498

Query: 452 SXXXXXXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVLSIRLR 501
           S               + LYD I DPIE  +L    +Y+ +      +L+
Sbjct: 499 SPEE------------MYLYDLIKDPIEKYDLAQKPEYQEVISKFKSKLK 536



 Score = 64.1 bits (149), Expect = 8e-09
 Identities = 42/126 (33%), Positives = 61/126 (48%), Gaps = 10/126 (7%)

Query: 16  LTSDVETPKNILFILIDDLRHLSD-----KKVYLPNINFLGKTGATFNNAFAQQALCAPS 70
           + S  + P N+LFI+ DDL    +      +   PN++   KTG +F NAFA    CAPS
Sbjct: 22  IQSATDKPYNVLFIIADDLNDYVNGLGGHPQSKTPNLDKFAKTGVSFTNAFANAGWCAPS 81

Query: 71  RNSLLTGRRPDSLRLYDFYSYWR-DRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSS 129
           R SL TG  P     +   +  R  +  G  N  T+  +FK++ Y +   GK  H  +  
Sbjct: 82  RASLHTGIAP----WHSGLAMKRVSKHKGLKNNFTLSDYFKKNNYYSIGTGKTEHGVEHK 137

Query: 130 NFTDDY 135
           N+T  Y
Sbjct: 138 NWTKHY 143


>UniRef50_A4ASX5 Cluster: Mucin-desulfating sulfatase; n=1;
           Flavobacteriales bacterium HTCC2170|Rep:
           Mucin-desulfating sulfatase - Flavobacteriales bacterium
           HTCC2170
          Length = 502

 Score = 94.7 bits (225), Expect = 5e-18
 Identities = 96/382 (25%), Positives = 175/382 (45%), Gaps = 44/382 (11%)

Query: 11  NGDRVLTSDVETPKNILFILIDDLRH----LSDKKVYL--PNINFLGKTGATFNNAFAQQ 64
           N +  +    + P+N++FIL DD R+     + K  +L  PN++ L + GA   N F   
Sbjct: 29  NNEDPVNPKKKKPRNVIFILTDDHRYDYMGFTGKVPWLETPNMDKLAQEGAYLPNTFVTT 88

Query: 65  ALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH 124
           +LC+PSR S+LTG+   S  + D      +++   G+ T  P++ ++ GY T   GK +H
Sbjct: 89  SLCSPSRASILTGQYSHSHTIVD------NQAPDPGDLTYFPEYLEKSGYQTGFFGK-WH 141

Query: 125 PGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLP 184
            G      D+    ++ +   P   +Y +  +  N      ER       V  +    + 
Sbjct: 142 MGSHG---DEPQPGFTHWESFPGQGVYYNPTLNING-----ER-------VSYKDSTYIT 186

Query: 185 DLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKD 244
           DL + ++ ID+LKKR+  KPFF  +     H   K  + +  +    ++  P   +  K 
Sbjct: 187 DLLT-EHTIDWLKKRDKDKPFFAYLSHKAVHAGFKPARRHKGKYKGKRIALPATYDQTKT 245

Query: 245 MPL--VSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLS 302
                + W  W   ++   I    + + +     +   ++   Y    L +DE +G ++ 
Sbjct: 246 GAYRDLKWPQWVADQR---ISWHGVDYMY--HDNRDIHEMVVDYCETLLGVDESVGAIMD 300

Query: 303 YVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVHEP 356
           Y+      + T+++   D+G+S GE+GL  K   ++ ++KVPL+ + P+L        + 
Sbjct: 301 YLKKEGLDESTMVIYMGDNGFSWGEHGLIDKRHFYEESVKVPLLVRCPELFDGGGTPAQM 360

Query: 357 VELIDIFPTLVDLTKLSDEIPK 378
           V+ IDI PT+  L +   E PK
Sbjct: 361 VQNIDIAPTI--LAEAGIEKPK 380


>UniRef50_A7A9X1 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 480

 Score = 94.3 bits (224), Expect = 7e-18
 Identities = 96/376 (25%), Positives = 177/376 (47%), Gaps = 54/376 (14%)

Query: 25  NILFILIDDLR-----HLSDKKVYLPNINFLGKTGATFNNAF----AQQALCAPSRNSLL 75
           NI+ IL DD+R      L  ++V  PN++ L      F NA        A+  PSR  L+
Sbjct: 26  NIILILADDMRASGMNFLGKEQVQTPNLDKLAGESTVFTNAHIMGGTSGAVSMPSRAMLM 85

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK----------VFHP 125
           TG+          Y+  +  +    + T I +  ++ GY+T+  GK           F  
Sbjct: 86  TGKY--------LYNLEKQGATIPNSHTMIGETLQKAGYNTFHTGKWHSSYEALNRCFKE 137

Query: 126 GKSSNFTDDYPYSWSE--YPYHPPTEMYKDAKVCRNK-KTKKLERNLICPVSVKRQPGQS 182
           GK+  F   + + W+   Y YH      K   V  N+ K+ K+E      +      G+ 
Sbjct: 138 GKAIFFGGMWDH-WNVPLYDYHADMNYGKRRPVIHNQAKSNKVEYE----IGEYMYSGKH 192

Query: 183 LPDLQSLDYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNI 241
             D+ + + A++++++ ++ ++PFFL++ +  PH P   P EY++    S++  P  PN 
Sbjct: 193 SVDIFTHE-AVEYIQQQKDKNQPFFLSVAYMSPHDPRSMPDEYMQLYDQSQIQLP--PNF 249

Query: 242 PKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILL 301
            +  P  +     ++  RD+I       P    P +    IR+ YYA   ++D+ +G ++
Sbjct: 250 MEKHPFDNG----ELEIRDEILA---AIPR--RPDEIKKHIRE-YYAMISHVDKRVGNII 299

Query: 302 SYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFK-SPKLIPTVVHEP 356
             +      + TII+   D+G ++G++GL  K + +++++ VPL+ K + +       + 
Sbjct: 300 QTLKDNGLYENTIIIFAGDNGLAVGQHGLMGKQNVYEHSVGVPLMIKAAAQHTGKKTADL 359

Query: 357 VELIDIFPTLVDLTKL 372
             LID+FPTL D+ +L
Sbjct: 360 CYLIDVFPTLCDMLQL 375


>UniRef50_A6DJ72 Cluster: Mucin-desulfating sulfatase; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Mucin-desulfating
           sulfatase - Lentisphaera araneosa HTCC2155
          Length = 495

 Score = 93.5 bits (222), Expect = 1e-17
 Identities = 104/370 (28%), Positives = 161/370 (43%), Gaps = 58/370 (15%)

Query: 25  NILFILIDDLRHLS---DKKVYL----PNINFLGKTGATFNNAFAQQALCAPSRNSLLTG 77
           N++FIL DD R  +    KK  L    P+IN +   G  F N +   +LC+PSR + L+G
Sbjct: 28  NVVFILTDDQRGDAVGYHKKPLLGIDTPSINKIAAEGVQFENMYCTTSLCSPSRAAFLSG 87

Query: 78  RRPDSLRLYD-FYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
               + ++YD F  Y  D         + P   ++ GY T  +GK +H G+     D   
Sbjct: 88  TYTHTHKVYDNFTDYPHD-------LKSFPLLLQQEGYTTGWIGK-WHMGEED---DSKR 136

Query: 137 YSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL 196
             +  +  H     Y D     N + KK+             PG     +   D AIDFL
Sbjct: 137 PGFDYWVTHKGQGKYWDTTFNVNGERKKV-------------PGYYAHKVT--DMAIDFL 181

Query: 197 KKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMP------LVSW 250
            K + SKPF L +G   PH P     +Y      + V  P       D P      L +W
Sbjct: 182 NKVDKSKPFALCLGHKAPHGPFIPEAKYDSIYNDTPVPYPDSSWKLGDKPKWIVDRLPTW 241

Query: 251 H----PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD- 305
           H    P    RK     + +    F            +SY A    +D+ +G +  +++ 
Sbjct: 242 HGIYGPLYGFRKDFPNDKASAIVDFE--------HFVRSYTATINSVDDSVGRIYDHLEE 293

Query: 306 ---MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVHEPVELI 360
              +  TI++ TSD+G+ LGE+G+  K +  + ++ +PL  + PK I   TV+ E V  I
Sbjct: 294 MGILDNTILIFTSDNGFLLGEHGMIDKRTMHEASVSIPLTVRFPKKIKGGTVIKEQVLSI 353

Query: 361 DIFPTLVDLT 370
           D+ PT+++LT
Sbjct: 354 DMAPTIMELT 363


>UniRef50_A6DQC0 Cluster: Mucin-desulfating sulfatase; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Mucin-desulfating
           sulfatase - Lentisphaera araneosa HTCC2155
          Length = 476

 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 105/381 (27%), Positives = 173/381 (45%), Gaps = 55/381 (14%)

Query: 15  VLTSDVETPKNILFILIDD--LRHLSDKKVYL------PNINFLGKTGATFNNAFAQQAL 66
           V+ ++ + P NI+FIL DD  L  +S    +L      PNI+ + K+G TF+N     ++
Sbjct: 6   VVLANPQKP-NIVFILSDDHALEAISAYGSWLKDHAKTPNIDRISKSGMTFHNMCVNNSI 64

Query: 67  CAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
           C+PSR S+LTG+   +  +   +   +  S        +P+  +  GY  Y VGK +H  
Sbjct: 65  CSPSRASILTGQYNHTNGVMKLHGKIKAGS------PWLPKELQAFGYQNYLVGK-WH-- 115

Query: 127 KSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDL 186
                 D  P  + ++        Y +            E+N        +  G S  D+
Sbjct: 116 -----LDSLPEGFEKFKIVDDQGEYFNPSFLD-------EQN-----QTVKTAGYST-DV 157

Query: 187 QSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKE--PNIPKD 244
            + D A+++L K   + PF L + F  PH P  +P+ Y   +  S++  P     ++ K 
Sbjct: 158 YT-DQALEWLSKHKSADPFMLMLNFKAPHYPYDYPERYESLLENSQIPEPLNLYEDLTKS 216

Query: 245 MPLVSWHPWTDVRK-RDDIRR-LNITFPFGVMP--TKWTLKIRQSY-YAAALYI------ 293
            P++    +  + K R   RR    T P         WT ++  +Y + +  YI      
Sbjct: 217 SPMLKNRCFGQMAKARSYFRRQYKSTTPEMSKDGVDTWTGQVSAAYQHMSKKYIRCITAV 276

Query: 294 DELIGILLSYVDMQK----TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLI 349
           DE +G +L Y++       TI++  SD G+ LG++GL+ K    D ++K+P I   PKLI
Sbjct: 277 DENVGRVLDYLEHNNLNDNTIVIYGSDQGYWLGQHGLYDKRLILDQSIKMPFIISYPKLI 336

Query: 350 PTVVH-EPVELIDIFPTLVDL 369
               + E    IDI PTL+DL
Sbjct: 337 KNNKNFELCSNIDIAPTLLDL 357


>UniRef50_Q7UMT6 Cluster: Mucin-desulfating sulfatase; n=2;
           Bacteria|Rep: Mucin-desulfating sulfatase -
           Rhodopirellula baltica
          Length = 524

 Score = 92.3 bits (219), Expect = 3e-17
 Identities = 103/388 (26%), Positives = 175/388 (45%), Gaps = 45/388 (11%)

Query: 21  ETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLL 75
           ++P NILFIL DD R           +  P+I+ + + GA    A+   +LC+PSR S+L
Sbjct: 40  DSPPNILFILCDDHRFDCLGVAGHPFLETPHIDTMARDGAMLRRAYVTTSLCSPSRASIL 99

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY 135
           TG+   + R+ D Y           N    P+  ++ GY T  +GK +H G      DD 
Sbjct: 100 TGQYAHNHRVVDNY------HAVDPNLVFFPESLQDAGYQTAFIGK-WHMGGD---IDDP 149

Query: 136 PYSWSEY-PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAID 194
              +  +  +      + D      +  +         V+ KR P +     +  +Y++D
Sbjct: 150 QRGFDHWVSFRGQGTYWPDGHGTTREVPQTTYDGF--NVNGKRVPQRGYITDELTEYSLD 207

Query: 195 FLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPN--IPKDMPLV---- 248
           +LK R+ +KPFFL +     H            +P  + HR +  N  +P ++P V    
Sbjct: 208 WLKGRDPNKPFFLYVSHKAVHADF---------VPADR-HRGRYDNEALPIEIPTVEAMD 257

Query: 249 SWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQK 308
           + +    VR + + R   + F + +      +  R+ Y  + L +D+ +G L  ++  Q+
Sbjct: 258 AGNKPMWVRNQRNSRH-GVDFGYNLPGFSPEVYYRR-YCESLLAVDDSVGQLREFLKQQE 315

Query: 309 ----TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVV--HEPVELIDI 362
               TI+V   D+G+  G++GL  K + ++ + KVPL+  +P  IP  V     V  IDI
Sbjct: 316 LDQNTIVVYMGDNGFQFGDHGLIDKRTAYEASAKVPLLVVAPGKIPAGVPFDGLVGNIDI 375

Query: 363 FPTLVDLTKLSDEIPKCLNHKDTSQ-LC 389
            PTL++    S   PK +N +   Q LC
Sbjct: 376 APTLLEAANAS--APKNINGQSVWQALC 401


>UniRef50_A6DMR1 Cluster: Iduronate sulfatase; n=2; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 607

 Score = 92.3 bits (219), Expect = 3e-17
 Identities = 84/366 (22%), Positives = 157/366 (42%), Gaps = 48/366 (13%)

Query: 25  NILFILIDDLRHLSD-----KKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           ++L I +DD    ++     ++   P+I  L + G TF+NA      C PSR +  TG  
Sbjct: 24  SVLIINVDDWNDWNEVLQGHQQAITPHIKRLAERGITFSNAICVSPSCVPSRPAFFTGIA 83

Query: 80  P---DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
           P    ++   +    WR  +  +    TIP+ F ++G+++  + K FH G    F    P
Sbjct: 84  PWRSGNISNDNGRRPWRFYAGQEA--VTIPKLFSQNGWESIGIAKNFHKGDKPEFDTYIP 141

Query: 137 YSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL 196
                    PP ++ K        K   +  N      +   P   + D ++    I+  
Sbjct: 142 ---------PPKKVNK-------VKGVGIRLNSSAVWDIADVPVTEMSDYKAASLGIE-- 183

Query: 197 KKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKE-----PNIPKDMPLVSWH 251
           K R+     FL++G ++PH+P   P++Y    P+  +  P+       ++P+   LV+  
Sbjct: 184 KIRSVKSSLFLSVGIYRPHVPWIVPQKYFDMYPLESLQLPEARSDDLDDLPERFKLVAGF 243

Query: 252 PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLS--YVD--MQ 307
                       +    +   ++   +  +  ++Y A+  + DE +G LL   Y     +
Sbjct: 244 E----------AKFGKGYHENLVKKGYDKQFVRAYLASVTFADEQVGRLLDAWYASPHAE 293

Query: 308 KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP-TVVHEPVELIDIFPTL 366
              ++L SDHG+ LGE   W+K   +  + +   +   P L    + ++ V L+D++PTL
Sbjct: 294 NGYVILWSDHGYMLGEKSAWSKIKPWYNSSRSNFMIAGPGLEKGAMCNKAVSLLDLYPTL 353

Query: 367 VDLTKL 372
           +DL  L
Sbjct: 354 IDLLGL 359


>UniRef50_A6DJ01 Cluster: Putative N-acetylglucosamine-6-sulfatase;
           n=1; Lentisphaera araneosa HTCC2155|Rep: Putative
           N-acetylglucosamine-6-sulfatase - Lentisphaera araneosa
           HTCC2155
          Length = 489

 Score = 91.9 bits (218), Expect = 4e-17
 Identities = 126/499 (25%), Positives = 212/499 (42%), Gaps = 67/499 (13%)

Query: 17  TSDVETPKNILFILIDDLRHLS----DKK---VYLPNINFLGKTGATFNNAFAQQALCAP 69
           T  V+   NIL+I  DD  H S    D+    V  PNI+ L ++G  F + +     C P
Sbjct: 14  TIAVDKKPNILYIFTDDQTHRSVSAYDEAHDWVQTPNIDKLAESGMRFTSCYTG-TWCQP 72

Query: 70  SRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSS 129
           SR S LTG    SL      +Y     + +      P  F++ GY+T  +GK +H G+  
Sbjct: 73  SRASKLTGLLQHSLDSLKITNYPMAEYDPK-TLPFFPAVFRQQGYETACIGK-WHLGEDV 130

Query: 130 NFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSL 189
               D+ YS           +  D    ++ K      +L+     +R+P       +  
Sbjct: 131 GHGRDWDYS-----------VIWDRGGPKSNKYAYFNNSLVRTNGGERKPLGGYTTDKFT 179

Query: 190 DYAIDFLKKRNG-SKPFFLAI---GFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDM 245
           + A+D++ K+N   KP++L +   G H P+ P K  K++ K + +        P   K  
Sbjct: 180 ELAVDYIHKQNDKEKPWYLWLCYPGVHGPYTPAKRHKDFYKDVEVKVPSDIFGPRHSKPA 239

Query: 246 PLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD 305
            L +   W    K+D     N T      P  +  ++++ Y+ A   +DE +G L+  ++
Sbjct: 240 HLKNMTRW----KKDK----NGT------PVGFASQVKK-YHNAVKSLDEAVGTLMKALE 284

Query: 306 ----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVHEPVEL 359
               ++ TI++ TSD G++ G++G   K+  +D  +  PLI K+P +    TV  E V  
Sbjct: 285 DSGQLENTIVIFTSDQGFAWGQHGSKEKWLPYDANIIAPLIIKAPGITQPGTVNGEAVCG 344

Query: 360 IDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSV 419
           +DI  T+ +L  +    P+   H         G+SL+P +++    L A  +        
Sbjct: 345 VDITVTIHELAGIE---PQWKMH---------GRSLMPLLKDPHKKL-ASPMLMINTTHR 391

Query: 420 YPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGI--ELYDHIIDP 477
           Y  K +++ + K+     Y    +R  Y  W+                +  ELYD   DP
Sbjct: 392 YGSKINEELKAKN-----YDAFKRRGLYA-WMMMRDGKYKYIRHFKDNVIEELYDLEKDP 445

Query: 478 IESKNLFLVSKYKNIAKVL 496
            E  NL +  +YK   K L
Sbjct: 446 KELNNLAINPEYKTKLKQL 464


>UniRef50_A6C2T4 Cluster: Sulfatase; n=1; Planctomyces maris DSM
           8797|Rep: Sulfatase - Planctomyces maris DSM 8797
          Length = 493

 Score = 91.9 bits (218), Expect = 4e-17
 Identities = 105/397 (26%), Positives = 178/397 (44%), Gaps = 68/397 (17%)

Query: 7   IILLN---GDRVLTSDVETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFN 58
           I+LLN    +++  +D + P N++ I+ D+     L    ++ +  P+I+ L K G  F 
Sbjct: 14  ILLLNFSFTEQLAAADQQRP-NVVIIMTDNHGEWTLGCYGNQDIKTPHIDQLAKEGTLFT 72

Query: 59  NAFAQQALCAPSRNSLLTGRRPDSLRLYDFY----SYWRDRSNGQGNFTTIPQFFKEHGY 114
            AFA  A+C+P+R S LTG  P    ++ F         D  N    F +IPQ   + GY
Sbjct: 73  RAFANNAVCSPTRASFLTGLMPCQHGVHCFLRTRIQTGPDSFNTLEEFQSIPQVLHDAGY 132

Query: 115 DTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVS 174
                GK +H G +    + + Y W   P+      Y D  V  N+K             
Sbjct: 133 VCGLSGK-WHLGDNLYPQEGFSY-WITKPHGGSAGFY-DQNVIENEK------------- 176

Query: 175 VKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVH 234
           ++++P   L DL +  + I F+K+ N  KPFFL + ++ P+      KE ++    ++  
Sbjct: 177 IRKEPTY-LTDLWT-QHGIRFIKQ-NQEKPFFLFLAYNGPYGLGSAMKEPIRNRFKAEYE 233

Query: 235 RPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKW--TLKIRQSYYAAALY 292
           +   P+ P++       PW               F +G     W   L I + Y A    
Sbjct: 234 KMTFPSFPREKA----QPW--------------NFNYG----DWIGDLGIIRKYAAEVSA 271

Query: 293 IDELIG-ILLSYVDM---QKTIIVLTSDHGWSLGENGLWA------KYSNFDYALKVPLI 342
           +D+ +G I+ +  D+   + T+++ T+D G S G +G W         + FD+ + +PLI
Sbjct: 272 VDDGVGQIMQTLKDLGLRENTLVIFTADQGLSGGHSGYWGMGDHTRPLTAFDWTMTIPLI 331

Query: 343 FKSPKLIPTVVHEP--VELIDIFPTLVDLTKLSDEIP 377
           F  P  I +   +   V   D++PTL++   L D+IP
Sbjct: 332 FSQPGKIVSGARQDMMVANYDVYPTLLNYLGLQDKIP 368


>UniRef50_Q650K5 Cluster: Choline-sulfatase; n=7; Bacteroidales|Rep:
           Choline-sulfatase - Bacteroides fragilis
          Length = 526

 Score = 91.5 bits (217), Expect = 5e-17
 Identities = 101/403 (25%), Positives = 174/403 (43%), Gaps = 53/403 (13%)

Query: 25  NILFILID----DLRH-LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           +I+FI+ D    D  H + +K V  PNI+ L + G+ F   ++      P+R  LLTG  
Sbjct: 52  HIIFIMSDQHRGDALHCMGNKAVISPNIDKLAQEGSLFVCGYSSAPSSTPARAGLLTGMS 111

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKV-FHPGKS-----SNFTD 133
           P     +    Y +  S  +     +PQ  ++ GY T+ +GK+ + P K+     +   D
Sbjct: 112 PWH---HGMLGYGKVASKYKYE---MPQMLRDLGYYTFGIGKMHWFPQKALHGFHATLVD 165

Query: 134 DYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAI 193
           +   S +        E ++     +N     +  N     + K +  +  P   +   A 
Sbjct: 166 ESGRSETRDFISDYREWFQLQAPGKNPDLTGIGWNNHNAGTYKLEE-RLHPTAWTGQTAC 224

Query: 194 DFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPW 253
           + ++  +  +P FL + F +PH P   PK YL           ++ +IP  +P V    W
Sbjct: 225 ELIRNYDSDQPLFLKVSFARPHSPYDPPKRYLDMY--------EKVDIP--VPFVG--DW 272

Query: 254 TD-VRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQK 308
                +R D  R++    F  +  ++ +  R+ YYA   +ID+ IG ++  +      + 
Sbjct: 273 CGKYAERKDPERVSKDAAFANLGEEYAVNSRRHYYANVTFIDDQIGQIIQTLKEKGMYEN 332

Query: 309 TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTV------VHEPVELIDI 362
            II  T+DHG  LG++  W K   ++ + K+P I K P  + T       + +PVEL D 
Sbjct: 333 AIICYTADHGDMLGDHYHWRKTYAYEGSAKIPYIIKWPSAMTTQAIRGKRIEQPVELRDF 392

Query: 363 FPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNG 405
            PT ++L      +P  +          +GKSLV     N NG
Sbjct: 393 LPTFIELA--GGTVPDDM----------DGKSLVALASGNKNG 423


>UniRef50_A6DG34 Cluster: Choline sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Choline sulfatase - Lentisphaera
           araneosa HTCC2155
          Length = 476

 Score = 91.5 bits (217), Expect = 5e-17
 Identities = 97/408 (23%), Positives = 182/408 (44%), Gaps = 64/408 (15%)

Query: 7   IILLNGDRVLTSDVETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAF 61
           + +LN   +  +  + P N +F+  DD     +R   +  ++ PN++ L ++G +F N +
Sbjct: 1   MFVLNTGGLFAASSQKP-NFVFLFADDQRADTIRAHGNDFIHTPNLDRLAESGFSFKNNY 59

Query: 62  A----QQALCAPSRNSLLTGRRPDSLRLYDFYSYWRD----RSNGQGNFTTIPQFFKEH- 112
                  A+C  SR  L+TGR            YW +    + NG  +   +P + KE  
Sbjct: 60  CAGSYSGAVCVASRAMLMTGR------------YWNNIPNVKKNGWASLDLLPTYLKEKA 107

Query: 113 GYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICP 172
           GY+TY +GK +H G  +              +     +Y       +    +++  +   
Sbjct: 108 GYETYIIGK-WHNGLHT----------LRAAFQNGASVYMGGMA--DHTDFEVQDFVAGQ 154

Query: 173 VSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISK 232
           +  KR+  +     +  + AI ++++    KPFFL + F  PH P   P EY ++     
Sbjct: 155 LQAKRR-AKEFSSTEFANSAIKYIEEAPSDKPFFLYVAFMAPHDPRNPPDEYRQR----- 208

Query: 233 VHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQ--SYYAAA 290
            +    P + K+   +  HP+ +V+     R   +       P + ++   Q   YY   
Sbjct: 209 -YYKNRPPLAKNYKAL--HPFRNVKFTTQGRDEGLAS----WPREKSVISDQLCEYYGLV 261

Query: 291 LYIDELIGILLSYVDMQK----TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP 346
            ++DE +G ++  +D  K    TII+ T+DHG ++G +GL  K + +++++K PLI  S 
Sbjct: 262 THLDEQVGRIIDAIDQSKHADNTIIIYTADHGLAMGSHGLLGKQNVYEHSMKAPLII-SG 320

Query: 347 KLIPTVVHEPVELI-DIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGK 393
           K +P         I D++ TL D  +++   P+ ++ K    L  EG+
Sbjct: 321 KTVPNGESAAFNYIHDLYATLCDYARIAK--PEAVDAKSLRPL-IEGE 365


>UniRef50_Q4V902 Cluster: Zgc:114066; n=17; Eumetazoa|Rep:
           Zgc:114066 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 538

 Score = 91.1 bits (216), Expect = 6e-17
 Identities = 84/357 (23%), Positives = 155/357 (43%), Gaps = 30/357 (8%)

Query: 23  PK-NILFILIDDLRHLSDKKVYLPNIN-FLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           PK NI+ IL DDL       + L      +G  G TF NAF    LC PSR S+LTG+ P
Sbjct: 31  PKPNIVLILTDDLDVSIGGMIPLVKTKKLIGDAGITFTNAFVASPLCCPSRASILTGKYP 90

Query: 81  DSLRLYDFYSYWRDRSNG--QGNF-TTIPQFFKEH-GYDTYSVGKVF--HPGKSSNFTDD 134
            +  + +        S    +G      P F ++H  Y T+  GK    +  K +   + 
Sbjct: 91  HNHHVVNNTLEGNCSSTAWQKGQEPDAFPAFLQKHAAYQTFFAGKYLNEYGSKKAGGVEH 150

Query: 135 YPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAID 194
            P  W  +        Y +  +  N + ++  +N              L D+ + + +ID
Sbjct: 151 VPLGWDHWFALERNSKYYNYTLSVNGRAQRHGQN---------YSEDYLTDVLA-NVSID 200

Query: 195 FLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWT 254
           FL+ ++  +PFF+ +    PH P     +Y    P  K   P++PN   ++     H W 
Sbjct: 201 FLENKSNRRPFFMMVSTPAPHSPWTAAPQYDSSFPDLKA--PRDPNF--NIHGKDKH-WL 255

Query: 255 DVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLT 314
             + +  +   ++ F       +W     ++  +    +++L+  L    ++  T ++ T
Sbjct: 256 IRQAKTPMSNASVEFLDNAYRKRW-----RTLLSVDDLVEKLVRKLDIRGELSNTYVIFT 310

Query: 315 SDHGWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHE-PVELIDIFPTLVDL 369
           SD+G+  G+  L   K   +++ ++VPL+ + P + P      P+  +D+ PT++D+
Sbjct: 311 SDNGYHTGQFSLPMDKRQLYEFDIRVPLLVRGPNIKPNQTSPLPIANVDLGPTILDI 367


>UniRef50_Q7UPQ8 Cluster: Choline sulfatase; n=4; Bacteria|Rep:
           Choline sulfatase - Rhodopirellula baltica
          Length = 477

 Score = 90.6 bits (215), Expect = 8e-17
 Identities = 100/369 (27%), Positives = 162/369 (43%), Gaps = 47/369 (12%)

Query: 25  NILFILIDDL-----RHLSDKKVYLPNINFLGKTGATFNNAFAQQ----ALCAPSRNSLL 75
           NI+FI  DDL       L +K+V  PN++ L + G +FN+A+       A+C  SR  L 
Sbjct: 31  NIIFIFADDLCFDSIAELGNKEVETPNLDRLAREGTSFNHAYNMGSWSGAVCLASRTMLN 90

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSN----F 131
           +GR     +  + Y+   +R   +G +    +  K  GY TY  GK      + N     
Sbjct: 91  SGRFV--WQAQEIYNQ-SERERQEGRWWG--EIMKAAGYRTYMTGKWHCRASAENSFDVV 145

Query: 132 TDDYPYSWSEYP--YHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSL 189
            D  P    ++P  Y+ P E   D     + K             V            S 
Sbjct: 146 RDTRPGMPKDFPEGYNRPIEGQPDPWSPSDPKWGGFWEGGTHWSEVIAN--------HSD 197

Query: 190 DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVS 249
           D+  D  K     +P F+ + F+  H P + P+EYL + P   +  P         PL  
Sbjct: 198 DFFADAAKH---DQPTFMYLAFNATHDPRQAPQEYLDKYPTENILVPANYQ-----PL-- 247

Query: 250 WHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKI-RQSYYAAALYIDELIGILLSYVDMQ- 307
            HP  +        R     PF    T++ +++ R+ YYA   ++D +IG +L  V+   
Sbjct: 248 -HPCAEEIGCGRNLRDERLAPFP--RTEYAVRVHRREYYALLTHMDAMIGRILDSVEASG 304

Query: 308 ---KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKL-IPTVVHEPVELIDIF 363
               T I  T+DHG ++G++GL  K + +D++++VP + K P +     V EP+ L D+ 
Sbjct: 305 KADNTWIFFTADHGLAVGQHGLLGKQNPYDHSVRVPFLVKGPGVKAGGRVEEPIYLQDVM 364

Query: 364 PTLVDLTKL 372
           PT ++L K+
Sbjct: 365 PTTLELAKV 373


>UniRef50_Q985M3 Cluster: Choline sulfatase; n=11;
           Proteobacteria|Rep: Choline sulfatase - Rhizobium loti
           (Mesorhizobium loti)
          Length = 509

 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 93/367 (25%), Positives = 146/367 (39%), Gaps = 46/367 (12%)

Query: 25  NILFILIDDLR--HLSDKK---VYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N L +++D L      D     ++ P++  L    A F N +    LCAP R S ++G+ 
Sbjct: 7   NFLIVMVDQLNGTFFPDGPAAFLHAPHLKALAARSARFRNNYTASPLCAPGRASFMSGQL 66

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNF-----T 132
           P    +YD      + +    +  T     +  GY T   GK+    P +   F     T
Sbjct: 67  PSRTEVYD------NAAEFASSIPTFAHHLRADGYHTVLSGKMHFVGPDQLHGFEERLTT 120

Query: 133 DDYPYSWSEYP-YHPPTEM----YKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQ 187
           D YP  +   P Y  P E     Y +          ++   +     V     Q L D  
Sbjct: 121 DIYPADFGWTPDYRKPGERIDWWYHNLGSVSGAGVAEISNQMEYDDEVAFHAVQKLYDFA 180

Query: 188 SLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPL 247
            +             +P+ L + F  PH P    ++Y           P+   IP D   
Sbjct: 181 RVS-------DDAAHRPWCLTVSFTHPHDPYVARRQYWDLYEDCPALEPEVGFIPCD--- 230

Query: 248 VSWHPWTD-VRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD- 305
            S  P +  + K  D    +IT        +   + R+ Y+A   Y+D+ +G LLS ++ 
Sbjct: 231 -SQDPHSQRLYKASDYNSFDIT-------AEQIRRSRRGYFANISYLDDKVGELLSVLER 282

Query: 306 ---MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDI 362
              +  TII+  SDHG  LGE GLW K   F+ + +VPL+     +   ++  PV  +D+
Sbjct: 283 TRMLDDTIILFCSDHGDMLGERGLWFKMCFFEGSARVPLMIAGKDIPAGLIKAPVSNLDV 342

Query: 363 FPTLVDL 369
            PTL DL
Sbjct: 343 TPTLCDL 349


>UniRef50_Q0D0R3 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus terreus NIH2624|Rep: Putative
           uncharacterized protein - Aspergillus terreus (strain
           NIH 2624)
          Length = 510

 Score = 89.8 bits (213), Expect = 1e-16
 Identities = 62/188 (32%), Positives = 91/188 (48%), Gaps = 16/188 (8%)

Query: 187 QSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMP 246
           +S  Y  D ++ RN  +PF L +    PH P    KE+       ++  PK   IP D  
Sbjct: 103 KSTQYLYDQVRYRN-DQPFCLTVSMTHPHDPYAITKEFWDLYEDVEIPLPKHSAIPHDQQ 161

Query: 247 LVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD- 305
                   D   +  ++ +++      +P       R++YYAA  Y+D  IG LL  ++ 
Sbjct: 162 --------DPHSQRVLKCIDLWNK--ELPEDRIRAARRAYYAACTYVDTNIGKLLRVLEE 211

Query: 306 ---MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPK-LIPTVVHEPVELID 361
               + TIIV T DHG  LGE GLW K + F+ + +VP+IF +PK   P  V E V  +D
Sbjct: 212 TGLSENTIIVFTGDHGDMLGERGLWYKMTWFENSARVPMIFHAPKRFAPHRVPENVSTMD 271

Query: 362 IFPTLVDL 369
           + PT  DL
Sbjct: 272 LLPTFADL 279


>UniRef50_Q7W424 Cluster: Putative sulfatase; n=2; Bordetella|Rep:
           Putative sulfatase - Bordetella parapertussis
          Length = 485

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 90/367 (24%), Positives = 162/367 (44%), Gaps = 48/367 (13%)

Query: 22  TPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           TP+N++ I+ D+     L     + V+ PN++ L   G  F +A+    +C P+R S  T
Sbjct: 4   TPQNMVVIMSDEHQSRALGCYGHEFVHTPNLDALAARGTRFASAYCTSPVCIPARASFAT 63

Query: 77  GRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
           G+  + +       +W +     G+  +     ++  +   S+GK+       ++  D+ 
Sbjct: 64  GKYINQI------GFWDNADAYDGSVPSWHHMLRDRDHQVVSIGKLHF----RDYGGDHG 113

Query: 137 YSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL 196
           +S    P H          + R+    +     +  ++   +   +  D + +  A  +L
Sbjct: 114 FSEEIIPMHIVGGKGDLMGLVRSDLPVRKGAYKMAQMAGPGESQYTFYDREIVSRAQIWL 173

Query: 197 KK---RNGSKPFFLAIGFHKPHIPLKFPKE-----YLKQMPISKVH-RPKEPNIPKDMPL 247
           ++   R+  KP+ L + F  PH PL  P E     Y + +P+ K++ R + P+       
Sbjct: 174 REQAPRHADKPWVLFVSFVSPHFPLTAPPEHYYRYYNRDLPLPKLYDRSQRPD------- 226

Query: 248 VSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD-- 305
              HP+    ++D     N    F     K   K +  YY    ++DE IG LL  +D  
Sbjct: 227 ---HPY----QQDYRGSFNYDDYFDPGLVK---KAQAGYYGLCSFLDENIGKLLGTLDDL 276

Query: 306 --MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT--VVHEPVELID 361
             +  T +V TSDHG +LG  G+W K + F+ A  VPLI  + + IP+   V+ PV  +D
Sbjct: 277 DILDSTRVVYTSDHGDNLGARGMWGKSNMFEEAAAVPLII-AGRDIPSGVTVNTPVSHVD 335

Query: 362 IFPTLVD 368
           + P + D
Sbjct: 336 VAPFIYD 342


>UniRef50_Q3W0K8 Cluster: Sulfatase precursor; n=1; Frankia sp.
           EAN1pec|Rep: Sulfatase precursor - Frankia sp. EAN1pec
          Length = 534

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 118/483 (24%), Positives = 190/483 (39%), Gaps = 45/483 (9%)

Query: 16  LTSDVETPKNILFILIDDL-RHLSDKKVYLPNINFLGK-TGATFNNAFAQQALCAPSRNS 73
           L +D + P N +FI  DDL    S     +P    L +  G TF  +FA   +C P+R S
Sbjct: 48  LAADTQRP-NFVFIPADDLDATTSPYWEAMPRTAALIRDAGLTFTESFAPTPICCPARGS 106

Query: 74  LLTGRRPDSLRLY----DFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSS 129
           LLTG+   +  +     D   +    +NG     T  ++ ++ GY+T  VGK  +  + +
Sbjct: 107 LLTGKYGHNTGVLTNSGDEGGWATFAANGNEE-RTFAKYLQDSGYNTALVGKYMNGIEDA 165

Query: 130 NFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSL 189
              D  P  W+E+        Y       N      E   I        P     D+ + 
Sbjct: 166 --PDHVPPGWTEWYGSVDNFFYTGYNYALN------ENGTIVHYGGPSDPANYSTDVVAA 217

Query: 190 DYAIDFLKKRNGS-KPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLV 248
             ++DFL++     +PF L      PH+PL  P       P +    P+ PN  +  P V
Sbjct: 218 K-SVDFLERAAAKDEPFMLYTASTAPHLPLP-PAPRDSNNPFTDDLAPRSPNYQE--PDV 273

Query: 249 SWHP-WTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQ 307
           S  P W  +R    +R   +     +    +  ++  S  A    + +++  L    ++ 
Sbjct: 274 SDKPAW--LRTSAGVRSAQVNL---INDNDYRNRMG-SLLALDDMVGDIVTTLRDTGELD 327

Query: 308 KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIFPTLV 367
            T +V TSD+G++LG + L  K + ++ +L+VPL+   P +        V  IDI PT +
Sbjct: 328 HTYLVFTSDNGYNLGAHRLIHKMAPYEESLRVPLVVAGPGVTRGTDDHMVAAIDIAPTFL 387

Query: 368 DLTKL---SD----EIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVY 420
           +L  +   +D     +   L  +D +Q  +    L  +      G +  A  Q P   + 
Sbjct: 388 ELAGVPVPADVDGMSLAPLLRGQDPAQ--WRSDLLGQYAGPGGQGDDGIAAEQVPGQPIV 445

Query: 421 PQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIES 480
                      DI      +RT RY Y  W               +  ELYD   DP E 
Sbjct: 446 AAATDPVAHYLDIPAWS-GLRTDRYTYVRWYD-------TDRTVVHERELYDLSNDPYEL 497

Query: 481 KNL 483
            NL
Sbjct: 498 TNL 500


>UniRef50_A6DM50 Cluster: Choline sulfatase; n=3; Lentisphaera
           araneosa HTCC2155|Rep: Choline sulfatase - Lentisphaera
           araneosa HTCC2155
          Length = 647

 Score = 89.0 bits (211), Expect = 3e-16
 Identities = 89/384 (23%), Positives = 159/384 (41%), Gaps = 43/384 (11%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDDLRHLS-----DKKVYLPNINFLGKTGA 55
           +I+ V  + +              N +FI  DD  + S        +  PN++ L K G 
Sbjct: 5   LIFTVVALTMTSQLSAAETASKKPNFMFIFADDQSYESIGAYGQLNIKTPNLDRLVKRGI 64

Query: 56  TFNNAFAQQA----LCAPSRNSLLTGRRPDSLRL-YDFYSYWRDRSNGQGNFTTIPQFFK 110
           +F + +   A    +C  SR  L +GR  +        Y +W    N  G  T +   + 
Sbjct: 65  SFTHTYNMGAWGGAVCVASRAMLNSGRFVNRAEKGVKQYPHWSQIMNSAGYTTYMTGKWH 124

Query: 111 EHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLI 170
            HG   + V K    G  +     Y  ++         E+Y+   +  +K+ +   R   
Sbjct: 125 VHGNPRFDVMKDVRGGMPNQTPARYKRTFKP-------ELYESEWLPWDKRQQGFWRG-- 175

Query: 171 CPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPI 230
                    G     + + +    F K +N +KPFF+ + F+ PH P + PKEY+   P+
Sbjct: 176 ---------GTHWTQVVADNTLTFFEKVKNDNKPFFMYLAFNAPHDPRQAPKEYVDMYPL 226

Query: 231 SKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAA 290
             +  P+  N   + P  +       + RD++      +P      K   + RQ YYA+ 
Sbjct: 227 DSIKIPE--NYMPEYPYAA--EICGKKLRDEVL---APYPRTTYAVK---RNRQEYYASI 276

Query: 291 LYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP 346
            Y+D  IG +L  ++     + T I+ T+DHG + G +GL  K S ++++++ P I   P
Sbjct: 277 TYMDHHIGRMLDALEASGKAENTYIIFTADHGLAAGHHGLMGKQSMYEHSMRPPFIVVGP 336

Query: 347 KLIP-TVVHEPVELIDIFPTLVDL 369
            +   + +  P+ L D   T ++L
Sbjct: 337 GIKQNSKIDTPIYLQDAMATAIEL 360


>UniRef50_A4W906 Cluster: Sulfatase precursor; n=10;
           Enterobacteriaceae|Rep: Sulfatase precursor -
           Enterobacter sp. 638
          Length = 501

 Score = 88.6 bits (210), Expect = 3e-16
 Identities = 113/413 (27%), Positives = 184/413 (44%), Gaps = 79/413 (19%)

Query: 25  NILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           N++ IL DDL +  D  +Y       PNI+ L + G  F+  +A   LC+PSR  LLTGR
Sbjct: 37  NVVIILADDLGY-GDLGIYGHPIVKTPNIDKLAQEGVRFSQYYAPAPLCSPSRAGLLTGR 95

Query: 79  RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
            P    +  +    ++ + G+ N  TI  + K+ GYDT  +GK +H     +  D     
Sbjct: 96  TPFRTGIRSWIPTNKNIALGR-NEKTIASYLKDQGYDTAMMGK-WHLNAGVDRHDQPQAE 153

Query: 139 WSEYPYHPPTEMYKDAKVCRN-KKTKKLERN-LICPVSVKRQPGQSLPDLQSL------D 190
            + + Y   T +     V  +  K K+  RN ++ P    R  G++L  +  +       
Sbjct: 154 DAGFDY---TLVNAAGFVTSDLDKAKERPRNGVVYPNGFYRN-GKALGTVNQISGEFVSQ 209

Query: 191 YAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSW 250
            AI++L  +  +KPFF+ + F + H PL  PK+YL      ++++       K  P + +
Sbjct: 210 EAINWLNDKKDNKPFFMYVAFTEVHTPLASPKKYL------EIYKNYMSEYEKQHPDMFY 263

Query: 251 HPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV----DM 306
             W D   R                          YYA   Y+DE +G +L+ +      
Sbjct: 264 ADWVDKPYRGP----------------------GEYYANISYMDEQVGKVLAKIKSMGQE 301

Query: 307 QKTIIVLTSDHG--------W----SLGE-NGLWAKYSN-FDYALKVPLIFKSPKLI--P 350
             TII+ TSD+G        W      GE +GL  +  N ++  ++VP I K  + +   
Sbjct: 302 DNTIIIFTSDNGPVTREARKWYELNMAGETDGLRGRKDNLWEGGIRVPAIIKYGQHLHAG 361

Query: 351 TVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNS 403
           TV   PV  +DI PTL +LT  +  +P       T ++  +G+S+VP +E  +
Sbjct: 362 TVTDTPVSGLDILPTLAELTHFN--LP-------TDRI-IDGESIVPVLEGQT 404


>UniRef50_Q0V1P8 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 561

 Score = 88.6 bits (210), Expect = 3e-16
 Identities = 100/382 (26%), Positives = 162/382 (42%), Gaps = 35/382 (9%)

Query: 3   YVVNIILLNGDRVLTSDVETPK-NILFILIDDLR-HLSDKKVYLP-NINFLGKTGATFNN 59
           Y+    L  G  + TS     K N +FI+ DD   HL     Y+P     LGK G  +  
Sbjct: 4   YIPASTLYIGTTIATSSTRHGKPNFVFIITDDQDLHLGSMD-YMPLTRKQLGKQGTFYKQ 62

Query: 60  AFAQQALCAPSRNSLLTGRRPDSLRLYD----FYSYWRDRSNGQGNFTTIPQFFKEHGYD 115
            +   ++C PSR SLLTG+   +  + D    +  Y +  S G  N   +P F +  GYD
Sbjct: 63  HYCTISICCPSRVSLLTGKAAHNTNVTDVNPPYGGYTKFISQGL-NDKYLPVFLQGAGYD 121

Query: 116 TYSVGKVFHPGKSSNFTDDYPYSW--SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPV 173
           TY  GK+ +   ++ +    P  W  +++   P T +Y +A           +++   P 
Sbjct: 122 TYYTGKLMNGHSTTTWNKPLPAGWNGTDFLVDPGTYIYWNA---------TFQKDQAPPA 172

Query: 174 SVKRQPGQSLPDLQSLDYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISK 232
                PGQ   DL   +  ++F+    N SKPFF+ I    PH        + K +    
Sbjct: 173 PA---PGQYNTDLVK-EKGLEFIDTVANTSKPFFIGIAPIGPHAEFNGTGGFTKAV---G 225

Query: 233 VHRPKEPNIPKDMPLVS-WHP--WTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAA 289
             R ++  +    P  S W+P   +       + +LN T        +W +   QS  + 
Sbjct: 226 AKRHQKLFLDAKAPRTSNWNPDKPSGASWISKLEKLNGTVI--ASHDEWHVGRLQSLQSV 283

Query: 290 ALYIDELIGILLSYVDMQKTIIVLTSDHGWSLGENGLW-AKYSNFDYALKVPLIFKSPKL 348
              +DE++  L  Y  +  T I+ TSD+G+ +G++ L   K   F+  + VP   + P +
Sbjct: 284 DELVDEVVNRLEKYKLLDNTYIIFTSDNGYHIGQHRLQPGKTCAFEEDINVPFYVRGPNV 343

Query: 349 IPTVVHEPVEL-IDIFPTLVDL 369
                 + V    DI PTL +L
Sbjct: 344 PKGKTVDVVTTHTDIVPTLFEL 365


>UniRef50_Q5LRB5 Cluster: Choline sulfatase; n=1; Silicibacter
           pomeroyi|Rep: Choline sulfatase - Silicibacter pomeroyi
          Length = 498

 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 97/372 (26%), Positives = 150/372 (40%), Gaps = 47/372 (12%)

Query: 20  VETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSL 74
           V T  NIL I+ D      L           ++  L      F NA+    +C P+R+  
Sbjct: 13  VRTRPNILLIMADQMTPFMLEACGGTGARTRHLTRLAGRAVQFTNAYTPSPICVPARSCF 72

Query: 75  LTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQF---FKEHGYDTYSVGKVFHPGKSS-- 129
           +TG    +   YD         NG    + +P F       GY+T   GK+   G     
Sbjct: 73  MTGLYTSTTGCYD---------NGDPYHSFLPTFAHYLTNAGYETVLSGKMHFIGADQLH 123

Query: 130 NFT-----DDYP--YSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQS 182
            F      D YP  + WS YP  P      DA       T +     I P   K      
Sbjct: 124 GFQRRLNPDIYPSGFLWS-YPLPPDG----DASFQAFDFTPQYLAENIGPGWSKELQYDE 178

Query: 183 LPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIP 242
               ++L+Y      +     P+ L + F  PH P   P+ Y +    + +  P   + P
Sbjct: 179 ETQFRALEYL-----RHAPDTPWMLTVSFTNPHPPYVVPRPYWEMYKDADIPLP---DYP 230

Query: 243 KDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLS 302
            DM          +R+   + +        V   +  + +R+ + A A Y+D+ IG LL 
Sbjct: 231 ADMDARYSEFDHALRRWHGLHQRG----HEVRDPRNLIAMRRGFAALAHYVDDKIGALLE 286

Query: 303 YVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVE 358
            +D      +T+I++TSDHG  LGE GL  K S ++++ ++PLI   P   P  V  PV 
Sbjct: 287 VLDETGQRDETVIIVTSDHGEMLGEKGLIQKRSLYEWSARIPLIIDLPGAAPGRVDTPVS 346

Query: 359 LIDIFPTLVDLT 370
           L+D+  TL++L+
Sbjct: 347 LLDLPATLIELS 358


>UniRef50_A3ZTV8 Cluster: Mucin-desulfating sulfatase; n=1;
           Blastopirellula marina DSM 3645|Rep: Mucin-desulfating
           sulfatase - Blastopirellula marina DSM 3645
          Length = 493

 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 116/478 (24%), Positives = 201/478 (42%), Gaps = 76/478 (15%)

Query: 25  NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N+LFIL DD R      +    +  P+++ L   G  F N +   +LC+PSR S+L+G  
Sbjct: 25  NVLFILTDDQRSDALSCMGHPHLKTPHVDRLADEGLLFKNHYCTTSLCSPSRASILSGLY 84

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
             +  + + ++ +        N  + P    E GY+T  +GK +H G+ +   D+    +
Sbjct: 85  AHAHGVVNNFTDY------PSNLVSFPMRLHESGYETAYIGK-WHMGEDN---DEPRPGF 134

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR 199
             +  H     Y D +   N + +K+       V                D A D++ K+
Sbjct: 135 DYFVTHKGQGKYFDTEFNFNGQGRKVVDGYYTTVVT--------------DMAEDWISKQ 180

Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMP------LVSWH-- 251
           +G KP+ L +G   PH      ++Y      + +  PK     +D P      L +WH  
Sbjct: 181 DGDKPWMLMLGHKAPHSFYLPEEKYEHTFDQADIQYPKSAFDLEDKPEWFKKRLDTWHGI 240

Query: 252 --PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV----D 305
             P  D RK           P GV   K   ++ ++Y+   L +D+ +G L  ++    +
Sbjct: 241 YGPLFDWRKNFPDES-----PAGV---KDFARMVRAYWGTILSVDDSVGRLYDFLKERGE 292

Query: 306 MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIFPT 365
           +  T+I+ TSD+G   GE+G+  K +  + ++++PL+ + P L P  V +P  +ID    
Sbjct: 293 LDNTLIIFTSDNGLLEGEHGMVDKRTGHEPSIRIPLVVRYPGLTP--VDQP-RVIDNISV 349

Query: 366 LVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQCPRPSVYPQKNS 425
            +D    +  I +    K    +   GKS     + +++           R S Y + N 
Sbjct: 350 TID---FAPSILEICGAKPLENI--HGKSWKQLAQGDASDW---------RTSFYYEYNY 395

Query: 426 DKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKNL 483
           +K      T    ++RT RY+Y  +               +  ELYD   DP E+KNL
Sbjct: 396 EKQ--FPYTPNVRALRTDRYKYIRY------PHGDGSPDKHMAELYDLKADPDENKNL 445


>UniRef50_Q15XR5 Cluster: Sulfatase precursor; n=1;
           Pseudoalteromonas atlantica T6c|Rep: Sulfatase precursor
           - Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 549

 Score = 85.8 bits (203), Expect = 2e-15
 Identities = 97/368 (26%), Positives = 152/368 (41%), Gaps = 47/368 (12%)

Query: 45  PNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTT 104
           PN++ L   G TF N F   ++C PSR ++LTG+   +  + D       R     +   
Sbjct: 74  PNLDALANEGMTFTNVFVTNSICTPSRATILTGQYSQTNGVLDL------RGKIATSQQH 127

Query: 105 IPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKK 164
           +P+  KE GY+T  +GK +H        D Y    S+  Y  P    +  K     +T+ 
Sbjct: 128 LPRLMKEAGYETAIIGK-WHLKAEPGAFDYYQVLESQGTYFDPEFRTRGPKPWPENETQ- 185

Query: 165 LERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEY 224
                          G S  D+ + D +I++L+ R  +KPFFL   F  PH   K+   Y
Sbjct: 186 -------------YTGHS-SDVVT-DLSIEWLENRVANKPFFLMHQFKAPHDMFKYAPRY 230

Query: 225 LKQMPISKVHRPKE-PNIPKDMPLVSWHPWTDVRKRD---DIRRLN----ITFPFGVMPT 276
              +    +  P +   + K    ++     D  + D    + R N    +    GV P 
Sbjct: 231 EDFLAAETIPEPDDLYAVAKTFGSIATRGKNDTLRADIGTSVSRRNNRRSMGIDLGVDPN 290

Query: 277 ----KWTLKIRQSYYAAALY----IDE----LIGILLSYVDMQKTIIVLTSDHGWSLGEN 324
               ++T +  Q Y  A L     +D+    LI  L      + TII+ TSD G  LGE+
Sbjct: 291 LSEEEFTRQAYQKYLKAYLRCVKGVDDNVARLIQTLRDTGQYKNTIIIYTSDQGMMLGEH 350

Query: 325 GLWAKYSNFDYALKVPLIFKSPKLIPTVVHEP--VELIDIFPTLVDLTKLSDEIPKCLNH 382
            L  K   FD ++++PLI K P    T +     +   D  P ++DL  +S   PK ++ 
Sbjct: 351 DLQDKRWIFDESIRMPLIVKHPDASETGIQSDLLINNTDFAPFILDLANIS--TPKYMHG 408

Query: 383 KDTSQLCF 390
           K      F
Sbjct: 409 KSFKTALF 416


>UniRef50_Q6UWY0 Cluster: Arylsulfatase K precursor; n=27;
           Euteleostomi|Rep: Arylsulfatase K precursor - Homo
           sapiens (Human)
          Length = 536

 Score = 85.8 bits (203), Expect = 2e-15
 Identities = 86/345 (24%), Positives = 146/345 (42%), Gaps = 37/345 (10%)

Query: 36  HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDR 95
           H   + V LP INF+   G +F NA+    +C PSR ++ +G              W + 
Sbjct: 49  HPGSQVVKLPFINFMKTRGTSFLNAYTNSPICCPSRAAMWSGL------FTHLTESWNNF 102

Query: 96  SNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAK 155
                N+TT     + HGY T   GK+ +     + ++       +  +    E      
Sbjct: 103 KGLDPNYTTWMDVMERHGYRTQKFGKLDYTSGHHSISNRVEAWTRDVAFLLRQEGRPMVN 162

Query: 156 VCRNK-KTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR--NGSKPFFLAIGFH 212
           + RN+ K + +ER                 D Q+ D A+++L+K   N ++PF + +G +
Sbjct: 163 LIRNRTKVRVMER-----------------DWQNTDKAVNWLRKEAINYTEPFVIYLGLN 205

Query: 213 KPHIPLKFPKEYLKQMPISKVHRPKE--PNIPKD-MPLVSWHPWTDVRKRDDIRRLNITF 269
            PH P   P    +    S  H        +  D + +  W P +++   D         
Sbjct: 206 LPH-PYPSPSSG-ENFGSSTFHTSLYWLEKVSHDAIKIPKWSPLSEMHPVDYYSSYTKNC 263

Query: 270 PFGVMPTKWTLKIRQSYYAAALYIDELIG---ILLSYVDM-QKTIIVLTSDHGWSLGENG 325
             G    K    IR  YYA     D ++G   + L  +D+ QKTI++ +SDHG    E+ 
Sbjct: 264 T-GRFTKKEIKNIRAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHGELAMEHR 322

Query: 326 LWAKYSNFDYALKVPLIFKSPKLIPTV-VHEPVELIDIFPTLVDL 369
            + K S ++ +  VPL+   P +   + V   V L+DI+PT++D+
Sbjct: 323 QFYKMSMYEASAHVPLLMMGPGIKAGLQVSNVVSLVDIYPTMLDI 367


>UniRef50_UPI0000519E45 Cluster: PREDICTED: similar to glucosamine
           (N-acetyl)-6-sulfatase isoform 2; n=1; Apis
           mellifera|Rep: PREDICTED: similar to glucosamine
           (N-acetyl)-6-sulfatase isoform 2 - Apis mellifera
          Length = 506

 Score = 85.0 bits (201), Expect = 4e-15
 Identities = 90/369 (24%), Positives = 157/369 (42%), Gaps = 38/369 (10%)

Query: 17  TSDVETPKNILFILIDDLRHLSDKKVYLPN-INFLGKTGATFNNAFAQQALCAPSRNSLL 75
           T      +NI+ I+ DDL    D    + N ++ +G  GATF+N F    +C P+R S+L
Sbjct: 23  TESCNCAENIVLIIADDLDLFLDGMTPMQNTLDLIGSKGATFSNCFVASPICCPNRASIL 82

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFF-----KEHGYDTYSVGKVFHP--GKS 128
           TG+   +  L    S     +N +      P  F     KE  Y T+  GK  +    K 
Sbjct: 83  TGKYQHN-HLVVNNSINGGCNNIEWQELQEPNTFAAYLKKEMFYTTFYAGKYLNQYGDKI 141

Query: 129 SNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQS 188
                  P  W  +        Y +  +  N   KK   +              L D+ S
Sbjct: 142 VGGAAHIPIGWDWWAGLIGNSKYYNYILSINGTEKKFGND----------SSDYLTDVIS 191

Query: 189 LDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLV 248
            D A +F+K  N ++PF + +    PH P   P     Q  I+K    K    P      
Sbjct: 192 -DMATNFIKTHNPNQPFLMVLAPPAPHAPF-IPA----QRHINKYKNVKAKRTP------ 239

Query: 249 SWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQK 308
           +++  T + K   ++R     P  ++P     +I ++ +   L +DEL+  +   + +Q 
Sbjct: 240 NFNTQTQMDKHWLVKREPSPLPDNLLPK--LDEIYRNRWETLLAVDELVKNIYQVLKLQS 297

Query: 309 ----TIIVLTSDHGWSLGENGLWA-KYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIF 363
               T I+ TSD+G+ +G+  +   K   ++  ++VPL+ + P ++P+ +  PV  +D+F
Sbjct: 298 FLNNTYIIFTSDNGYHIGQFSMPIDKRQPYETDIRVPLLIRGPGIMPSKIVAPVSSVDLF 357

Query: 364 PTLVDLTKL 372
            T++ +  L
Sbjct: 358 DTILGIAGL 366


>UniRef50_A0JAV7 Cluster: Sulfatase precursor; n=1; Shewanella
           woodyi ATCC 51908|Rep: Sulfatase precursor - Shewanella
           woodyi ATCC 51908
          Length = 526

 Score = 84.2 bits (199), Expect = 7e-15
 Identities = 93/379 (24%), Positives = 166/379 (43%), Gaps = 45/379 (11%)

Query: 18  SDVETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRN 72
           S  +   N+LFI+ D+++           V  PN++ L   G  +  A+    +C+PSR 
Sbjct: 17  SSSQAQDNLLFIMTDEMKWNVMGVAGHPVVKTPNLDRLASEGTYYKTAYTVAPICSPSRR 76

Query: 73  SLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKV-FHPGKSSNF 131
           S  T R      + D  S     ++G+ +  TI    K  GY T   GK+ F+P      
Sbjct: 77  SFFTSRYTHVHGVID-NSKQALANDGEVDLQTI---LKHQGYRTAISGKLHFYPEWHDWG 132

Query: 132 TDDYPYSWSEYPYHPPTEMYKDAKVCRNKKT--KKLERNLICPVS-VKRQPGQ---SLPD 185
            D++    SE P     E Y+   V ++     K ++ ++  P   +    G+      D
Sbjct: 133 FDEFWARSSEGPNR--LETYRQYMVAKHGDDAFKPIKGSVTYPKDPLGHDLGRYRFGKED 190

Query: 186 LQSL---DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIP 242
            ++    D A+D+L ++   KPFFL + +++PH P      Y+   P + ++ PK   +P
Sbjct: 191 FETYWLTDKALDYLARKE-KKPFFLFLSYNEPHSP------YMVTEPYASMYDPKTLPVP 243

Query: 243 KDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLS 302
                        + K+   +  ++     +   +    +   Y      +D+ +G +LS
Sbjct: 244 VIPASAKAERKVALEKKIKGKSRHL-----IDDEQMMRDLTAQYLGHVSNVDDNVGRVLS 298

Query: 303 YVDMQ----KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLI--------P 350
           Y+D       TI+V T+DHG  LG++G W K    + + ++PLI ++ K           
Sbjct: 299 YLDSSGLADNTIVVFTADHGNMLGDHGKWFKGVMHEGSSRIPLIIRAGKHTRYAKVMNRG 358

Query: 351 TVVHEPVELIDIFPTLVDL 369
            VV + VE ID+ PTL+++
Sbjct: 359 RVVEQVVESIDVMPTLLEM 377


>UniRef50_Q029P1 Cluster: Sulfatase precursor; n=1; Solibacter
           usitatus Ellin6076|Rep: Sulfatase precursor - Solibacter
           usitatus (strain Ellin6076)
          Length = 467

 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 104/366 (28%), Positives = 152/366 (41%), Gaps = 49/366 (13%)

Query: 45  PNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTT 104
           PN + L   G  F NAF     C PSR SL TGR P   R+    SY    S       T
Sbjct: 52  PNTDRLAGEGVRFGNAFVHAPQCVPSRVSLHTGRYPHVHRV-PTNSYDLPESE-----QT 105

Query: 105 IPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKK 164
           + +    +GY T  VG++  P     +T  +    +          Y         K  K
Sbjct: 106 LAKVLNANGYRTACVGEM--PFAPRAYTGGFQQVLAS------NREYDQFLAGHGLKFPK 157

Query: 165 LERNLICPVSVKRQPGQSLPDLQSL--DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPK 222
            +     P      P     D  +    +A DFLK  N  +PFFL I F +PH P   P 
Sbjct: 158 SDG----PFQAAPVPWTDDLDETAFFAGHARDFLKA-NRDRPFFLDINFRRPHHPFNPPA 212

Query: 223 EYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKI 282
            + K M +     P     P +M   +  P       +     ++ F    M      ++
Sbjct: 213 PFDK-MYLGAAFPPSHAR-PGEM--ANKPPQQKAALEN-----SVGFDLRSMTPADLDRV 263

Query: 283 RQSYYAAALYIDELIGILLSYVDMQ----KTIIVLTSDHGWSLGENGLWAKYS-NFDYAL 337
           +  YY      D+ IG +L  +  Q    +T++V  +DHG  LG++GL  K S  +D   
Sbjct: 264 KAYYYGMISENDKYIGTVLDELKSQGLEDRTVVVFNADHGEMLGDHGLLFKGSYMYDGVT 323

Query: 338 KVPLIFKSPKLIP--TVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSL 395
           +VPLI ++P  +P  TVV   VE +D+ PTL++L  L  ++P  +          +GKSL
Sbjct: 324 QVPLILRAPGKLPARTVVDGLVEEVDVMPTLLEL--LGIDVPAGV----------QGKSL 371

Query: 396 VPFIEN 401
           VP  +N
Sbjct: 372 VPLADN 377


>UniRef50_Q01RE9 Cluster: Sulfatase precursor; n=4; Bacteria|Rep:
           Sulfatase precursor - Solibacter usitatus (strain
           Ellin6076)
          Length = 499

 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 85/362 (23%), Positives = 155/362 (42%), Gaps = 35/362 (9%)

Query: 16  LTSDVETPKNILFILIDDLRH----LSDKKVYL--PNINFLGKTGATFNNAFAQQALCAP 69
           L +     +N++FIL DD R+        + +L  P+++ L + GA   NAF   ALC+P
Sbjct: 21  LLAQARRRRNVIFILSDDHRYDALGFMHPQPWLRTPHLDTLARDGAHLKNAFVCTALCSP 80

Query: 70  SRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTI-PQFFKEHGYDTYSVGKVFHPGKS 128
           SR S+LTG       +Y    +  D +      T   PQ  +  GY T  VGK +H G+ 
Sbjct: 81  SRASILTG-------VYAHRHHIVDNNTAIPRGTRFFPQLLQRAGYKTGFVGK-WHMGRE 132

Query: 129 SNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQS 188
            +        W  +               R + +   ERN +  V  K  P +     + 
Sbjct: 133 GDDPQPGFDKWVSF---------------RGQGSYLPERNGL-NVDGKHVPQKGYITDEL 176

Query: 189 LDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLV 248
            DYA+D+L+     +P+FL +     H     P +  K     +  RP    + +  P  
Sbjct: 177 TDYALDWLRTVPKEQPYFLYLSHKAVHADF-IPADRHKGAYAKETFRPPT-TMDESGPNA 234

Query: 249 SWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQK 308
              P     +R+    ++  +   +   ++  +  ++       +D ++  L     +  
Sbjct: 235 QHRPMWVQNQRNSWHGVDFPYHSDLDVGEYYKRYAETLLGVDDSVDRMLDALRERGQLDS 294

Query: 309 TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVHEPVELIDIFPTL 366
           T+++   D+G+  GE+GL  K + ++ +++VPL+ + P++     VV   V  +DI PT+
Sbjct: 295 TLVIYMGDNGFQFGEHGLIDKRTAYEESMRVPLLARCPEMFSGGRVVDRMVAGLDIMPTV 354

Query: 367 VD 368
           +D
Sbjct: 355 LD 356


>UniRef50_Q2U5H2 Cluster: Sulfatases; n=9; Pezizomycotina|Rep:
           Sulfatases - Aspergillus oryzae
          Length = 598

 Score = 83.4 bits (197), Expect = 1e-14
 Identities = 95/380 (25%), Positives = 161/380 (42%), Gaps = 37/380 (9%)

Query: 13  DRVLTSDVETPKNILFILIDDLRHLSDKKVYLPNIN-FLGKTGATFNNAFAQQALCAPSR 71
           D +  +D     NI+FIL+DD     D   Y P+ N ++   G  + N F   ALC PSR
Sbjct: 34  DIIRNNDTHGRPNIVFILVDDQDLQMDSLSYTPHTNHYIRDQGVFYKNHFVTTALCCPSR 93

Query: 72  NSLLTGRRPDSLRLYDFY----SYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGK 127
            SL TG++  +  + + Y     Y +  S G  N   +P + ++ GY+TY  GK+F+   
Sbjct: 94  VSLWTGKQAHNTNVTEIYPPYGGYPKFVSEGH-NENWLPLWLQDAGYNTYYTGKLFNAHT 152

Query: 128 SSNFTDDYP--YSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPD 185
             N+   +   ++ S++   P T  Y      RN            P+S   Q    +  
Sbjct: 153 VDNYNLPFAKGFNTSDFVLDPYTYQYLHPVYQRNHDP---------PISYSGQHTIDVLR 203

Query: 186 LQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDM 245
            ++LD   D + + +  +PFFL I    PH    F           +   P      KD+
Sbjct: 204 KKALDLLDDAVAESH-ERPFFLTIAPIAPH--SNFEMTNASDYTTFRFSAPIPLERHKDL 260

Query: 246 PLVSWHPWTDVRKRDDIRRLN--ITFPFGVMPTKWTLKIRQSYYAAALY----IDELIGI 299
                 P T+    D    +N   T P      + ++     +Y A L     +DE++  
Sbjct: 261 FPEVKVPRTEHFNPDQPSGVNWISTLP---QQNQSSIDSNDEFYRARLRALQGVDEIVEQ 317

Query: 300 LLSYVD----MQKTIIVLTSDHGWSLGENGLW-AKYSNFDYALKVPLIFKSPKLIPT--V 352
           ++  ++    +  T I  TSD+G+ +G++ L   K   F+  ++VP+  + P  IP+   
Sbjct: 318 IVQRLEDAGVLDNTYIFYTSDNGYHIGQHRLHPGKECGFEEDIRVPMFIRGPG-IPSGEE 376

Query: 353 VHEPVELIDIFPTLVDLTKL 372
           V      ID+ PT+ ++  L
Sbjct: 377 VGFVTTHIDLAPTIFEIAGL 396


>UniRef50_P15586 Cluster: N-acetylglucosamine-6-sulfatase precursor;
           n=21; Deuterostomia|Rep: N-acetylglucosamine-6-sulfatase
           precursor - Homo sapiens (Human)
          Length = 552

 Score = 83.4 bits (197), Expect = 1e-14
 Identities = 93/389 (23%), Positives = 162/389 (41%), Gaps = 40/389 (10%)

Query: 25  NILFILIDDLRHLSDKKVYLPNINFL-GKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
           N++ +L DD   +      L     L G+ G TF++A+   ALC PSR S+LTG+ P + 
Sbjct: 48  NVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNH 107

Query: 84  RLYDFYSYWRDRSNGQGNF---TTIPQFFKEH-GYDTYSVGKVF--HPGKSSNFTDDYPY 137
            + +        S          T P   +   GY T+  GK    +    +   +  P 
Sbjct: 108 HVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPL 167

Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
            WS +        Y +  +  N K +K   N     SV       L D+ + + ++DFL 
Sbjct: 168 GWSYWYALEKNSKYYNYTLSINGKARKHGEN----YSV-----DYLTDVLA-NVSLDFLD 217

Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVR 257
            ++  +PFF+ I    PH P     +Y  Q     V  P+  N   ++   + H W   +
Sbjct: 218 YKSNFEPFFMMIATPAPHSPWTAAPQY--QKAFQNVFAPRNKNF--NIHGTNKH-WLIRQ 272

Query: 258 KRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDH 317
            +  +   +I F       +W     Q+  +    +++L+  L    ++  T I  TSD+
Sbjct: 273 AKTPMTNSSIQFLDNAFRKRW-----QTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDN 327

Query: 318 GWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEP-VELIDIFPTLVDLTKLSDE 375
           G+  G+  L   K   +++ +KVPL+ + P + P    +  V  ID+ PT++D+      
Sbjct: 328 GYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGY--- 384

Query: 376 IPKCLNHKDTSQLCFEGKSLVPFIENNSN 404
                   D ++   +G SL+P +   SN
Sbjct: 385 --------DLNKTQMDGMSLLPILRGASN 405


>UniRef50_Q7UH28 Cluster: Mucin-desulfating sulfatase; n=2;
           Bacteria|Rep: Mucin-desulfating sulfatase -
           Rhodopirellula baltica
          Length = 534

 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 95/363 (26%), Positives = 156/363 (42%), Gaps = 53/363 (14%)

Query: 23  PKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTG 77
           P+N++FIL DD R           +  PN++ +   G    NAF   +LC+PSR S+LTG
Sbjct: 56  PRNVVFILTDDHRFDAMGCAGHPFLETPNLDSIAANGTHIKNAFVTTSLCSPSRASILTG 115

Query: 78  RRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPY 137
                 R+ D      +R    G     PQ+ +  GYDT  VGK    G   +    + +
Sbjct: 116 LYTHKHRVID-----NNRLVPDGTL-FFPQYLQRAGYDTAFVGKWHMGGHHDDPRPGFDH 169

Query: 138 SWSEY----PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAI 193
            W  +     Y PP   Y       N   +++           +Q G    +L   DYA+
Sbjct: 170 -WVSFRGQGNYLPPGPKY-----TLNVNGERV-----------KQKGYITDEL--TDYAV 210

Query: 194 DFLKKRNGSKPFFLAI---GFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSW 250
           D+LK+R+  +PFFL +     H    P +  +       +S +   KE +  K+ P   W
Sbjct: 211 DWLKERDDDEPFFLYLSHKAVHSNFTPAERHQGRYADEDLSFLPTGKELSADKNTP--RW 268

Query: 251 HPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIG-ILLSYVDM--- 306
                VR   D +       F     K    + + Y  + L +D+ +G +L    DM   
Sbjct: 269 -----VR---DQKNSWHGIDFSYHSDKGLDYLYRRYCESVLAVDDSVGRVLQQLKDMGIH 320

Query: 307 QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVHEPVELIDIFP 364
             T+I+   D+G+  GE+GL  K  +++ +++VP++ + P L      +   V  ID+ P
Sbjct: 321 DDTLIIYMGDNGFMWGEHGLIDKRVSYEASIRVPMLMQCPNLFDGGQPIENVVGNIDVGP 380

Query: 365 TLV 367
           T++
Sbjct: 381 TIL 383


>UniRef50_A6DIE0 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;
           Lentisphaera araneosa HTCC2155|Rep:
           N-acetylgalactosamine 6-sulfatase - Lentisphaera
           araneosa HTCC2155
          Length = 527

 Score = 80.6 bits (190), Expect = 9e-14
 Identities = 103/414 (24%), Positives = 178/414 (42%), Gaps = 57/414 (13%)

Query: 1   MIYVVNIILLNGDRVLTS---DVETPKNILFILIDDLRHL---------SDKKVY-LPNI 47
           M+ + NIIL     +LT      +   N++ I++DDL +          +D K Y  P  
Sbjct: 1   MLTLKNIILPVLTLMLTGTSLQAQQKPNVVVIIVDDLGYADMSFLPQAPTDIKHYKTPGF 60

Query: 48  NFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQ 107
           + L  TG  F NA+A   +C+PSR  +LTG          + +YW        N  TIP+
Sbjct: 61  DRLFATGTYFENAYATSPICSPSRAGILTGSYQQR-----WGNYWYGDGKFPNNKVTIPE 115

Query: 108 FFKEHGYDTYSVGKVFHPGKSSNFTDDYPY-SWSEYPYHPPTEMYKDAKVCRNKKTKKLE 166
               +GY T   GK    G        + +  +  + +H    +    K     K KK  
Sbjct: 116 MLSSNGYATAKYGKTHLSGWEKKVPTMHGFDEYLGFMHHTWDYIRLSQKDVDAYKKKKEF 175

Query: 167 RNLICPV--SVKRQPGQSLPDLQSLDY------------AIDFLKKRNGSKPFFLAIGFH 212
           ++  C V   + +  GQ   +L+ + Y            AI+F+K+  G KPF+L + ++
Sbjct: 176 KDFGCQVIGPLVKAEGQGNEELKPVSYENSFTTDIFTDEAINFIKRDKGGKPFYLHLSYN 235

Query: 213 KPHIPLKFPKEYLKQMPISKVHRPKEPNIPK-DMPLVSWHPWTDVRKRDDIRRLNITFPF 271
             H+P    +E   +  +   + P + N  K + P   W P  +  K            +
Sbjct: 236 AVHMPTYVVEETWAK-KVGARYVPWDRNAAKWEYPY--WDPAQEPHK-------TFHKKW 285

Query: 272 GVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLG--ENG 325
           G M  ++  + R+ Y A    +D  I  LL  ++     + T+I+ TSD+G ++    N 
Sbjct: 286 GHM-GEYDSEGRRCYLANLFALDYGISRLLDALEKSGQRENTMIIFTSDNGGTVNTYSNN 344

Query: 326 L---WAKYSNFDYALKVPLIFKSPKLIP-TVVHEP--VELIDIFPTLVDLTKLS 373
                +KY   +  ++VP+I   P  +P  +V++   V  +DI PT+ +LT ++
Sbjct: 345 APLRGSKYMLGEGGIRVPVIISMPGTLPQNIVNKSALVSGMDIMPTIAELTGIA 398


>UniRef50_Q2U8N6 Cluster: Sulfatases; n=1; Aspergillus oryzae|Rep:
           Sulfatases - Aspergillus oryzae
          Length = 644

 Score = 80.6 bits (190), Expect = 9e-14
 Identities = 63/198 (31%), Positives = 96/198 (48%), Gaps = 19/198 (9%)

Query: 25  NILFILIDDLRHLSDKKVYLPNI--NFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDS 82
           NILFIL DD   L     ++P +  N + K GAT+   +   ALC PSR +L TGR P +
Sbjct: 21  NILFILTDDQGKLIGGLDHMPKLQENLIQK-GATYPKHYCSVALCCPSRANLWTGRMPHN 79

Query: 83  LRLYDF---YSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP--Y 137
             + D    Y  +    +   N   +P + +E GYDTY VGK+++     N+ + Y   +
Sbjct: 80  TNITDVGLPYGGYPKVVSAGWNDNYLPIWMQEAGYDTYYVGKLWNSHTEENYNNPYAKGF 139

Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
           + S++   P T  Y +AK+ RN +T         PVS   Q    +   +SL +  + L 
Sbjct: 140 NGSDFLLDPWTYRYYNAKMTRNGET---------PVSYAGQYSTDVIKNKSLGFLDEAL- 189

Query: 198 KRNGSKPFFLAIGFHKPH 215
             N  +P+ L I  + PH
Sbjct: 190 -ANPDRPWMLTIAPNAPH 206


>UniRef50_A0Q2E3 Cluster: N-acetylgalactosamine 6-sulfate sulfatase;
           n=1; Clostridium novyi NT|Rep: N-acetylgalactosamine
           6-sulfate sulfatase - Clostridium novyi (strain NT)
          Length = 483

 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 88/376 (23%), Positives = 165/376 (43%), Gaps = 66/376 (17%)

Query: 25  NILFILIDDLRHLS-----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N++ I+ DD  + S     +     P ++ L   G  F N F    +C+P+R S+ TGR 
Sbjct: 7   NVISIITDDQGYWSMGCYGNHDAITPTLDSLANNGIRFENFFCVSPVCSPARASIYTGRI 66

Query: 80  PDSLRLYDFYSYWRDRSNGQGNF---TTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
           P    ++D+   W +    +      +T      ++GY+    GK +H G +    + + 
Sbjct: 67  PSQHGIHDWLDEWNNGYTTEEYLKGQSTFVDILAKNGYECAMSGK-WHLGVADKPQNGFK 125

Query: 137 YSWSEY----PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYA 192
           Y +S      PY+    MYKD  +   ++                     + D+ + DY 
Sbjct: 126 YWYSHQKGGGPYY-GAPMYKDGTLIHEER--------------------YVTDVMT-DYG 163

Query: 193 IDFL-KKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWH 251
           ++F+ K+R+   PF+L++ +  PH P   P+ + K++ +      +  + PKD     W 
Sbjct: 164 LEFIEKQRDSDNPFYLSLNYTAPHAPWS-PENHPKEL-LDLYKDCEFKSCPKD-GKNDWS 220

Query: 252 PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQ 307
                 K +D RR                ++ + Y+AA   +D  I  ++  +     ++
Sbjct: 221 IDYIFPKTEDERR----------------EVLRGYFAALTSVDNNIKRVIDKLKEMGVLE 264

Query: 308 KTIIVLTSDHGWSLGENGLWAK------YSNFDYALKVP-LIFKSPKLIPTVVHEPVELI 360
            T+I+ TSD+G ++G +G++ K       + FD ++K+P  I K   + P V  + +   
Sbjct: 265 NTLIIFTSDNGMNMGHHGIFGKGNGTSPVNMFDTSVKIPCFITKIGDIKPQVSTDLLSHY 324

Query: 361 DIFPTLVDLTKLSDEI 376
           DI PTL++   + DEI
Sbjct: 325 DIRPTLMEYLGIEDEI 340


>UniRef50_A6DHW4 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;
           Lentisphaera araneosa HTCC2155|Rep:
           N-acetylgalactosamine 6-sulfatase - Lentisphaera
           araneosa HTCC2155
          Length = 512

 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 109/383 (28%), Positives = 159/383 (41%), Gaps = 55/383 (14%)

Query: 25  NILFILIDDLRHL-------SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTG 77
           NI+ IL DDL +        ++  V  P ++ L  +G  F+NA++   +C+ SR  L TG
Sbjct: 21  NIIIILADDLGYADVGFHDYTEADVKTPELDKLASSGTWFSNAYSTSPICSASRLGLSTG 80

Query: 78  RRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVF-------HPGKSSN 130
           R         + +Y+           TI +  K  GY T  VGK         HP     
Sbjct: 81  RYQQR-----WGAYYYGEGGLPKEEQTIAEALKSIGYKTMKVGKTHMNKGFKQHP-MDHG 134

Query: 131 FTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKT-KKLERNLICPVSVKRQPGQSLPDLQSL 189
           F D   +    + +   ++ + DA   R KK   K     + P+    +   S  D    
Sbjct: 135 FDDFLGFIDHSWDFFMLSQEHLDAYKKRAKKAGHKGNIKFLGPLMRGYEKNASFKDTNIT 194

Query: 190 D-YAIDFLK--KRNGSKPFFLAIGFHKPHIPLKF-PKEYLKQMPISKVHRPK-EPNIPK- 243
           D + ++  K    N  +PF+L + F+  H PL   P+E  K+  I    +PK +PN    
Sbjct: 195 DVFTVEAQKFIVENKDEPFYLRLSFNAVHTPLHLVPEELAKKHGIK---QPKWDPNASTW 251

Query: 244 DMPLVSWHPWTDVRKR--DDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILL 301
           + PL  W P T         +  L    P+G          R  Y      ID+ IG +L
Sbjct: 252 EYPL--WDPKTLKYNEWYKQVCHLQNPDPYG----------RLKYLIHLEMIDQAIGKIL 299

Query: 302 SYVDMQK----TIIVLTSDHG---WSLGENG-LWA-KYSNFDYALKVPLIFKSPKLIPTV 352
             +D Q+    T+I  +SD+G    S   NG L A KYS  D AL VP +   P  +P  
Sbjct: 300 KTLDEQQIRDNTLIFFSSDNGGSHQSYANNGHLNAFKYSVMDGALHVPFLVSYPAKLPKA 359

Query: 353 VHEP--VELIDIFPTLVDLTKLS 373
                 V  +DIF T+ DLT LS
Sbjct: 360 NKSDALVSHMDIFATIADLTGLS 382


>UniRef50_A6C1Q0 Cluster: N-acetylgalactosamine 6-sulfate sulfatase;
           n=1; Planctomyces maris DSM 8797|Rep:
           N-acetylgalactosamine 6-sulfate sulfatase - Planctomyces
           maris DSM 8797
          Length = 469

 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 57/198 (28%), Positives = 98/198 (49%), Gaps = 22/198 (11%)

Query: 25  NILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N++ I+ DD     +    +++++ P+++ +GK GA F NAF    +C+PSR + L+GR 
Sbjct: 31  NLISIVTDDQGRWAMGLYGNRQIHTPHMDQIGKQGAVFTNAFVATPVCSPSRATFLSGRF 90

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
           P  L++ D+ S    +        T P+  ++HGY T  +GK +H G+ + F        
Sbjct: 91  PTELKITDWISSEEAQEGAGLTAMTWPEVLQQHGYQTALIGK-WHLGELNQF-------- 141

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR 199
                HP  + +          T+ +   L      +++ G SLPDL  +D AI+F+ + 
Sbjct: 142 -----HPHEKGFGHFMGFLAGGTRPMNPTLEIKGETQKRKG-SLPDL-LVDDAINFI-RT 193

Query: 200 NGSKPFFLAIGFHKPHIP 217
           +  KPF L + F  PH P
Sbjct: 194 SKDKPFALCLHFRAPHTP 211



 Score = 47.6 bits (108), Expect = 8e-04
 Identities = 49/179 (27%), Positives = 85/179 (47%), Gaps = 27/179 (15%)

Query: 264 RLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM----QKTIIVLTSDHGW 319
           ++++    GV+P +   K ++ YYA+   +D  IG LL  +D     + T+++ TSDHG+
Sbjct: 227 KIDVPITPGVIPEQIRQKNKE-YYASVSSVDRNIGRLLKELDQLRLAENTLVIFTSDHGY 285

Query: 320 SLGE-------NGLW-------AKYSN-FDYALKVPLIFKSPKLIP--TVVHEPVELIDI 362
           + G        NG W        K  N +D +++VPL+ + P +I   T   E V  ID+
Sbjct: 286 NNGRHGVSTKGNGHWIAGGVTGPKRPNMWDTSIRVPLVMRWPAVIKPGTQFDEIVSNIDM 345

Query: 363 FPTLVDLTKLSDEIPKCLNHKDTSQLCF-----EGKSLVPFIENNSNGLEAFAISQCPR 416
           F  ++   K+       L+  D S L F       K+L    + ++NGL    + + P+
Sbjct: 346 FKFVLGALKIPQPANLKLHGIDYSPLLFGQPAPVRKALFGQYDLHNNGLAYLRMIRTPK 404


>UniRef50_Q7UFA5 Cluster: Putative sulfatase yidj; n=1; Pirellula
           sp.|Rep: Putative sulfatase yidj - Rhodopirellula
           baltica
          Length = 527

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 89/358 (24%), Positives = 152/358 (42%), Gaps = 43/358 (12%)

Query: 42  VYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGN 101
           V  P+I+ +   GA   + +A   +C PSR +  TGR P +       +Y  DR   +G+
Sbjct: 94  VETPSIDSIAARGAICTSFYATSPVCTPSRAAFFTGRYPQNTG-----AYQNDRPL-RGD 147

Query: 102 FTTIPQFFKEHGYDTYSVGK--VFHPGKSSNFTD-DYPYSWSEYPY---HPPTEMYKDAK 155
             T  +  +  GY T   GK  +  PGK     D  + +S + Y +   H     +++ +
Sbjct: 148 MVTFAEVLRRDGYATGYAGKWHLDGPGKPQWGPDRQFGFSDNRYMFNRGHWKKFDFENGQ 207

Query: 156 VCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPH 215
                  KK + N      +     ++       D A DF+++ +  +PF   +    PH
Sbjct: 208 PSVAATNKKGQPN----YDLNGADEKTFSTDWLCDRAADFIRE-HSQEPFCYHLSLPDPH 262

Query: 216 IPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMP 275
            P    + Y        V  P    +  D P   W P T+   R+  +R N         
Sbjct: 263 GPNTVRQPYDTMFENMPVRPPMTFQLDGDQP--GWLPATN---RNSQQRFN--------- 308

Query: 276 TKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYS 331
                ++   Y+     ID+ +G+LLS +D     ++T++V TSDHG    E+G   K +
Sbjct: 309 ----ARLMTQYFGMVRCIDDNVGMLLSLLDELSLTKRTVVVFTSDHGDLCYEHGRLNKGN 364

Query: 332 NFDYALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQ 387
            ++ + KVP+I  +P LI     + + +  +D  PTL+ L  L  E+P     +D S+
Sbjct: 365 PYEGSAKVPMIIAAPGLISAGLRIDQAMGTVDFAPTLLSL--LRKEVPAGTQGRDLSE 420


>UniRef50_Q28M80 Cluster: Sulfatase; n=3; Rhodobacteraceae|Rep:
           Sulfatase - Jannaschia sp. (strain CCS1)
          Length = 770

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 94/370 (25%), Positives = 152/370 (41%), Gaps = 30/370 (8%)

Query: 17  TSDVETPKNILFILIDDL------RHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPS 70
           T D     NI  I +DD+      R     ++  P+++ L   G  F+NA+A   LCAP 
Sbjct: 4   TKDSVAGGNICVIWVDDMIDVFTWRKTFGLEIQTPHLDRLMSEGVRFSNAYATVPLCAPC 63

Query: 71  RNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSN 130
           R  L TG  P    L D   +WRD    +  +       + +G+  ++ GKV      SN
Sbjct: 64  RAELATGISPFRSGLVDLNRFWRDVYPPEKAWA---YDLRRNGFYNFTTGKV-----DSN 115

Query: 131 FTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNL-ICPVSVKRQPG---QSLPDL 186
           +    P  +    +H   ++  + K  R      L+R   I  V+     G    +  D 
Sbjct: 116 Y-KPMPEEYRRLLFH--EDVLAEDKGRRRGVHAYLDRGPGIKGVNHPDDDGSYDHTFFDN 172

Query: 187 QSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMP 246
           +    AIDFL + + ++   + +GF  PH  L  P  +  Q   + +     P+I     
Sbjct: 173 RVAQNAIDFLGRADPNRRHLIQLGFKHPHYNLVAPDRFYAQYDPADI---VWPSIAAPED 229

Query: 247 LVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD- 305
                P   V +   I     T P       W   +R +Y+A   ++D  IG  +  +  
Sbjct: 230 YFGPQPGFAVYEAAYIANGAWT-PEKAGDNAWRQVVR-AYFACISHVDHEIGRFMDALRT 287

Query: 306 ---MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDI 362
               + T ++  SD+G++LG +  + K S +D A  +PL      L P V   PV L +I
Sbjct: 288 SPFAENTTVIFLSDNGFNLGNHDSFHKMSQWDSAAHIPLGLWHAGLEPRVEPIPVSLHNI 347

Query: 363 FPTLVDLTKL 372
             T++DL  L
Sbjct: 348 PKTIMDLAGL 357


>UniRef50_A6DK33 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate-2-sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 499

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 107/421 (25%), Positives = 165/421 (39%), Gaps = 59/421 (14%)

Query: 21  ETPKNILFILIDDL-RH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLL 75
           E   NI+FI +DDL  H    +       P ++ L   G  FNNA  Q   C P+RNSL+
Sbjct: 19  EEKPNIIFIEVDDLPAHYIGAMGADFAETPTLDRLASEGVFFNNAVCQGTQCGPARNSLI 78

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKV-FHPG-------K 127
            G  P ++ +Y    +         +  T+P+  ++ GY T  +GK   HP        K
Sbjct: 79  AGVYPHNIGMYQNGPF----KGLAPDVWTLPRALQKAGYKTAHIGKSHIHPSNEGLSGTK 134

Query: 128 SSNFTDDYPYSWSEYPYHPPTEMY---KDAKVCRNKKTKKL-ERNLICPVSVKRQPGQSL 183
               T+ +     +Y +          K+AK   +     L E      +   R    SL
Sbjct: 135 EEVRTEGHRRLGFDYVWQSLGRAVVGGKEAKKGEDAYVDFLIEEAYFDQMKADRGKPTSL 194

Query: 184 PDLQSLDYAIDFLKKR---NGSKPFFLAIGFHKPHIPLKFPKEYL-----KQMPISKVHR 235
           PD   LD     L K+      +P+FL + +  PH P    + Y       Q+P      
Sbjct: 195 PDDIYLDGLFTDLAKKFIAEQEQPYFLWLNYSVPHGPYDVKQAYHDRFVDAQIPEPNAKH 254

Query: 236 PKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDE 295
            K   IPK++      P  D  K +  ++ N            ++        A +   E
Sbjct: 255 DKGEGIPKEL---RPSPLKDFSKLEKTQKGNCA----------SIAFMDDQLKAIIEAVE 301

Query: 296 LIGILLSYVDMQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT-VVH 354
             G      +   TIIV  SDHG  +GE+GL  K + +   L   L+   P+   + VV 
Sbjct: 302 TSG------EKDNTIIVFFSDHGILVGEHGLHHKTTLYKEVLNPSLVIYDPRQKRSKVVS 355

Query: 355 EPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQC 414
           +PV+L+D+  T +     SDE        D ++    G SLVP +         +A+ +C
Sbjct: 356 QPVQLLDLVSTALAWGNASDE--------DKAKP--YGDSLVPLLTGEGEFARDYAVGEC 405

Query: 415 P 415
           P
Sbjct: 406 P 406


>UniRef50_A4CMB1 Cluster: Arylsulphatase A; n=3; Bacteria|Rep:
           Arylsulphatase A - Robiginitalea biformata HTCC2501
          Length = 459

 Score = 78.6 bits (185), Expect = 4e-13
 Identities = 72/228 (31%), Positives = 112/228 (49%), Gaps = 29/228 (12%)

Query: 25  NILFILIDDLRH--LSDK---KVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NIL IL+DDL +  LS +    +  PNI+ L   G  F N +A   +C+PSR +LLTGR 
Sbjct: 43  NILCILVDDLGYGDLSCQGATDLQSPNIDALAANGMRFTNFYANSTVCSPSRAALLTGRY 102

Query: 80  PDSLRLYDFYSYWRDRSNGQGNF----TTIPQFFKEHGYDTYSVGKVFHPG-KSSNFTDD 134
           PD + +       ++  N  GN       IP      GY T  +GK +H G +  +  +D
Sbjct: 103 PDLVGVPGVIR--QNPENNWGNLADDAVLIPSELNPAGYHTGIIGK-WHLGLEEPDTPND 159

Query: 135 YPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAID 194
             +++ +       + Y D +        +L R  I        P     DL + D+ ID
Sbjct: 160 RGFTYFKGFLGDMMDDYWDHR-RGGINWMRLNREEI-------DPKGHATDLFT-DWTID 210

Query: 195 FLKKRNG-SKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNI 241
           FLK+R G  +PFFL + ++ PH P++ P+E+L ++      R +EPN+
Sbjct: 211 FLKERQGEEQPFFLYLAYNAPHFPIQPPREWLDKV------REREPNL 252


>UniRef50_Q5UEW6 Cluster: Probable phosphonate monoester hydrolase;
           n=1; uncultured alpha proteobacterium EBAC2C11|Rep:
           Probable phosphonate monoester hydrolase - uncultured
           alpha proteobacterium EBAC2C11
          Length = 512

 Score = 78.2 bits (184), Expect = 5e-13
 Identities = 97/390 (24%), Positives = 163/390 (41%), Gaps = 48/390 (12%)

Query: 15  VLTSDVETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAP 69
           ++ +++    NI+ I+ D  R      L    +  PN++ L   G +F N F    +C  
Sbjct: 14  LVRAEMHAKPNIVLIMTDQQRADTIGALGSPWMQTPNLDRLVNEGTSFTNCFVTSPVCVS 73

Query: 70  SRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKV-FHP--- 125
           SR S+  G  P +  +Y  +  W      + N+    ++  + GY   ++GK+  +P   
Sbjct: 74  SRASIFLGGYPHTTNVYTNFETW------EPNWV---KWLSDSGYHCVNIGKMHINPYDA 124

Query: 126 --GKSSNF---TDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLER----------NLI 170
             G    F     D P    ++      E  K  KV R +K  +  R          NL 
Sbjct: 125 KGGFHQRFFVENKDRPLFLEDHERAIYDEWDKALKVRRLEKPSRYTRVRDNRDAFLKNLG 184

Query: 171 CPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPI 230
           C            PD    + A  +L  R    PFFL IGF  PH P     ++L     
Sbjct: 185 C--FTWEIDDDMHPDNFVGNTASWWLNDRKAESPFFLQIGFPGPHPPYDPTGDFL----- 237

Query: 231 SKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNI-TFPFGVMPTKWTLKIRQSYYAA 289
           S     K P+       +   P    + R  +   NI +  +    T   +++   YY+A
Sbjct: 238 SIYKDTKFPHRAASQRELEKQPEMHKQLRQSMIDFNIDSVAWRENLTDDDIQLLHRYYSA 297

Query: 290 AL-YIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFK 344
            +  ID  +G +LS ++    +  TI++  SDH  +LGE+G   K++ +D   +VPLIF 
Sbjct: 298 NVSMIDCQVGQILSTLEQRGYLDNTIVIFCSDHADALGEHGHIQKWTMYDCVTRVPLIFW 357

Query: 345 SPKLIPT--VVHEPVELIDIFPTLVDLTKL 372
           +PK +       + V+L+DI PT+++   +
Sbjct: 358 APKTVKMQHQCADLVQLMDIAPTILNFANI 387


>UniRef50_A3JPC9 Cluster: Mucin-desulfating sulfatase; n=1;
           Rhodobacterales bacterium HTCC2150|Rep:
           Mucin-desulfating sulfatase - Rhodobacterales bacterium
           HTCC2150
          Length = 492

 Score = 78.2 bits (184), Expect = 5e-13
 Identities = 83/368 (22%), Positives = 157/368 (42%), Gaps = 46/368 (12%)

Query: 25  NILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NI+ I  D+     L    + +++ PN++ L  TG TF+N+F     C+P R S+LTG+ 
Sbjct: 6   NIILIFTDNQQAATLGCYGNDEIHTPNLDLLSDTGVTFDNSFCANGFCSPCRASVLTGKL 65

Query: 80  PDSLRLYDF-----YSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDD 134
           P    ++ +      + W    +      T+P+  K  GY T  +GK +H G+ ++    
Sbjct: 66  PSEHGVHSWLDDRKMADWPKDWHALDGLNTLPKALKSQGYSTALIGK-YHLGQPTS---- 120

Query: 135 YPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICP-VSVKRQPGQSLPDLQSLDYAI 193
                       P E +      ++   +   RN I          G S+      +  I
Sbjct: 121 ------------PAEGFDKWVTLQDGHIRSFYRNKIFDNGDAYDHVGHSVDFF--TNKGI 166

Query: 194 DFLKKR-NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHP 252
           +F+++      PFFL + +  P+      KE  +    ++       +IP++    +   
Sbjct: 167 EFIEQETQNENPFFLYLPYPAPYGHWPATKETDENRHTARYADCPMNSIPREPLSKAAVD 226

Query: 253 WTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQK 308
              +R  D+   ++ +    +M     L   +++Y+    ID+ +G ++  +D     + 
Sbjct: 227 GYMLRAADNSTHMDFSM---LMRAPNDLATLRNFYSQISMIDDGVGKIMETLDRLNIAED 283

Query: 309 TIIVLTSDHGWSLGENGLWAK-----YSNFDYAL-KVPLIFKSPKLIPTVVHEP--VELI 360
           T+++ T+DHG S GE+G W        SN   A  K+P+I + P +    +     V  I
Sbjct: 284 TLLIFTTDHGLSTGEHGFWGHGAATVPSNLHRAAHKIPMIMRQPNVTKPGLRNKLMVSNI 343

Query: 361 DIFPTLVD 368
           D+F T++D
Sbjct: 344 DVFATILD 351


>UniRef50_A3HTC7 Cluster: Putative uncharacterized protein; n=1;
           Algoriphagus sp. PR1|Rep: Putative uncharacterized
           protein - Algoriphagus sp. PR1
          Length = 1174

 Score = 78.2 bits (184), Expect = 5e-13
 Identities = 107/410 (26%), Positives = 172/410 (41%), Gaps = 55/410 (13%)

Query: 8   ILLNGDRVLTSDVETP---KNILFILIDDLR-----HLSDKKVYLPNINFLGKTGATFNN 59
           I  N  +V + + ++P    NI+FIL DD R     +  ++ V  P ++ L ++G  F  
Sbjct: 13  IPFNATKVFSQETKSPLNRPNIIFILTDDQRFDALGYAGNQFVQTPEMDRLAESGTYFET 72

Query: 60  AFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSV 119
           A     +CA SR SL TG      R ++F ++       +    + P   K  GY T   
Sbjct: 73  AIVTTPICAASRASLFTGLYE---RAHNF-NFQTGNIRAEYMEESYPTILKNSGYYTAFF 128

Query: 120 GKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQP 179
           GK  +  +  N  + +     EY  +     Y D    R    K +  +    V + R  
Sbjct: 129 GK--YGVRYDNLNNQF----DEYESYDRNNQYPDK---RGYYFKTIAGD---TVHLTRYT 176

Query: 180 GQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEP 239
           GQ          A+DF+ K    KPF L++ F  PH     P +Y  Q     +   +  
Sbjct: 177 GQK---------ALDFIDKAPEDKPFSLSLSFSAPHAHDGAPDQYFWQTTTDPL--LQNT 225

Query: 240 NIP-KDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYID-ELI 297
            IP  D+    +        RD   RL  T+ +     K+   ++  YY     ID E+ 
Sbjct: 226 TIPGPDLGEDEFFQAQPQFVRDGFNRLRWTWRYDT-EEKYQHSLK-GYYRMISGIDLEIA 283

Query: 298 GI--LLSYVDMQK-TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKL-IPTVV 353
            I   L    + K T+I++  D+G+ LGE  L  K+  +D +++VPLI   P+      +
Sbjct: 284 KIREKLKEKGLDKNTVIIVMGDNGYFLGERQLAGKWLMYDNSIRVPLIIYDPRSGNHQDI 343

Query: 354 HEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNS 403
            + V  ID+  T+ DL  +  E P+           ++GKSL+P +E  S
Sbjct: 344 KDMVLNIDVPATIADLAGV--ETPE----------SWQGKSLMPIVEGKS 381


>UniRef50_A4QZC6 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 637

 Score = 78.2 bits (184), Expect = 5e-13
 Identities = 99/390 (25%), Positives = 175/390 (44%), Gaps = 46/390 (11%)

Query: 25  NILFILIDDLRHLSDKKVYLPNIN-FLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
           NI+ I+ DD     D   ++P +   L + G TFNN +  +A C PSR ++L G++  + 
Sbjct: 27  NIIMIMTDDQDLHLDSTEHMPTLQKLLVQRGTTFNNHWVTEAQCCPSRATVLRGQQAHNT 86

Query: 84  RL----YDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
            +    Y   +Y + R++ + +   +P++  + GY T  +GK  +     N+    P +W
Sbjct: 87  NITAVRYPGGNYDKWRAS-EMDSEYLPKWLNDAGYSTNYIGKFLNGHNLGNYNPP-PKAW 144

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK- 198
           +E        MY   +   +K  +        PV+    PG    D+  +  A++ +K+ 
Sbjct: 145 TEIDALIDPYMYDFNRAVFSKNGQH-------PVN---YPGWHQTDIVRIK-AVERIKQL 193

Query: 199 RNGSKPFFLAIGFHKPHI--PLKFPKEYLKQMPISKVHRPKEPN--IPKDMPLVSWHPWT 254
               KPFF  I    PH   P+  P + + Q P+++ H+   P+  +PK     +W+P  
Sbjct: 194 AQDDKPFFYWISPTAPHTVPPINGPSDNMPQ-PLTR-HKDLFPDLVLPKK---GNWNP-P 247

Query: 255 DVRKRDDIRRLNITFPFG---VMPTKWTLKIR-QSYYAAALYIDELIGILLSYVDMQKTI 310
           D   +  +  +  T P     +  T+   K R QS       I++++  L     +  T 
Sbjct: 248 DEYAKQKVNWVGRTPPLNESMLAETEVLYKTRIQSLQGIDEIIEDVVATLEQEGILDNTY 307

Query: 311 IVLTSDHGWSLGENGLWA-KYSNFDYALKVPLIFKSPKLIPTVVHE-PVELIDIFPTLVD 368
           I+ TSD+G+ +G + + A K   +  A + P I + P +   VV   P    DI PTL++
Sbjct: 308 IIYTSDNGFMIGTHRITAMKSLAYKEAGQTPFIVRGPGVPEGVVSRLPGTHTDIAPTLLE 367

Query: 369 LTKLSD-EIPKCLNHKDTSQLCFEGKSLVP 397
           L  +     PK           F+G+SL+P
Sbjct: 368 LAGVDPASFPK----------LFDGRSLLP 387


>UniRef50_Q01PN7 Cluster: Sulfatase precursor; n=1; Solibacter
           usitatus Ellin6076|Rep: Sulfatase precursor - Solibacter
           usitatus (strain Ellin6076)
          Length = 496

 Score = 77.8 bits (183), Expect = 6e-13
 Identities = 84/368 (22%), Positives = 152/368 (41%), Gaps = 43/368 (11%)

Query: 22  TPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           T  NIL ++ D  R        ++ ++ PN++ L  +G  F NA++    C P+R  LLT
Sbjct: 23  TRPNILLLMADQWRADCLGAAGNRAIHTPNLDQLAASGVRFTNAYSATPTCTPARAGLLT 82

Query: 77  GRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKV-FHPGKSSNFTDDY 135
           G  P +      +   R    G      +P+  ++ GY T ++GK+ +HP +  N    +
Sbjct: 83  GLAPWN------HGMLRYAEVGARYPVEMPRALRDAGYYTAAIGKLHYHPQR--NVHGYH 134

Query: 136 PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLI------CPVSVKRQPGQSLPDLQSL 189
                E       +   D +     +   L+ +                P +  P   + 
Sbjct: 135 QALLDESGRIESPDFRSDYRSWFWSQAPNLDPDATGLGWNDFDARPYTLPERLHPTTWTG 194

Query: 190 DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVS 249
             A  +++    S+PFFL + F +PH P   P    +        R ++  +P    +  
Sbjct: 195 QTAASWIETYQRSEPFFLKVSFARPHSPYDPPDRLWR--------RYQDAPLPP-AAVAG 245

Query: 250 WHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD---- 305
           W      R        +     G +  +   + RQ YY +  ++DE IG ++  +     
Sbjct: 246 WASRYAARSGPQPDAWH-----GDLGAEQVRRSRQGYYGSVTFVDEQIGRIMESLTRRGL 300

Query: 306 MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT-----VVHEPVELI 360
           + +T+IV  SDHG  LG++ LW K   +  + +VP + + P+ + T      + + VEL 
Sbjct: 301 LDQTLIVFFSDHGDMLGDHNLWRKSYAYAGSSRVPFLVRWPEGMLTARRGGTIDQMVELR 360

Query: 361 DIFPTLVD 368
           D+ PT +D
Sbjct: 361 DVLPTFLD 368


>UniRef50_A6DNI8 Cluster: Putative N-acetylglucosamine-6-sulfatase;
           n=1; Lentisphaera araneosa HTCC2155|Rep: Putative
           N-acetylglucosamine-6-sulfatase - Lentisphaera araneosa
           HTCC2155
          Length = 705

 Score = 77.8 bits (183), Expect = 6e-13
 Identities = 103/393 (26%), Positives = 172/393 (43%), Gaps = 56/393 (14%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDDLRH----LSDKKVYL--PNINFLGKTG 54
           M Y+  I+ L  + +L +D + P NI+FIL DD ++          +L  PNI+ +   G
Sbjct: 2   MKYLFIILALFANTMLAAD-KGP-NIIFILTDDQKYDAMGFMGHYPFLKTPNIDRIRNEG 59

Query: 55  ATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGY 114
             F N+F   ++CAP+R   LTG  P   ++    +    R   Q    + P   +  GY
Sbjct: 60  VHFKNSFVTLSMCAPARAGFLTGTYP---QVNGVCTNVEGREFNQNKTPSFPLLLQRAGY 116

Query: 115 DTYSVGK--VFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICP 172
           +T   GK  + H  K     D +  S+S    +   ++  D K+  N             
Sbjct: 117 ETGFFGKWHLDHSNKPRLGFDRW-VSFSGQGKYNGNDLNIDGKLVHN------------- 162

Query: 173 VSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGF---HKPHIPLKFPKEYLKQMP 229
                 PG    +L   DYA+DF+ K N  KPF + +     H+P  P K      K   
Sbjct: 163 ------PGYITDELT--DYALDFIDK-NSDKPFCVYLSHKAVHQPFTPAKRHSSLYKGET 213

Query: 230 ISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITF--PFGVMPTKWTLKI----- 282
           + K     + N+ KD P   W       ++    R N T   P    P  +T +      
Sbjct: 214 VPKKESFFD-NL-KDKP--KWQRVNLPPEKLYRLRYNNTHETPAVKTPRPYTKENGSHPH 269

Query: 283 RQSYYAAALYIDELIGILLSYVDMQK----TIIVLTSDHGWSLGENGLWAKYSNFDYALK 338
            + Y  A   +DE IG + + ++ +K    T+I+   D+G+ LGE+    K  +++ +++
Sbjct: 270 TKDYLRAIAAVDEGIGKIYALLENKKILDNTVIIFAGDNGYLLGEHQRGDKRVHYNESMR 329

Query: 339 VPLIFKSPKLIP--TVVHEPVELIDIFPTLVDL 369
           +PLI + P  IP  + + + V  ID+ PT++D+
Sbjct: 330 IPLIMRYPAKIPADSTLDQMVLNIDVAPTILDI 362


>UniRef50_Q5UEW7 Cluster: Putative sulfatase; n=1; uncultured alpha
           proteobacterium EBAC2C11|Rep: Putative sulfatase -
           uncultured alpha proteobacterium EBAC2C11
          Length = 460

 Score = 77.4 bits (182), Expect = 8e-13
 Identities = 80/311 (25%), Positives = 137/311 (44%), Gaps = 39/311 (12%)

Query: 74  LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--PGKSSNF 131
           ++TGR P ++ ++D      +      +  T   + +  GY T   GK+    P +   F
Sbjct: 1   MMTGRIPSNVGVFD------NAGEFLSSEPTFAHYLRALGYQTTLCGKMHFVGPDQLHGF 54

Query: 132 -----TDDYP--YSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLP 184
                TD YP  Y W+   +    E Y  +++  +     +E  L C  S++    + + 
Sbjct: 55  ERRLTTDIYPSDYGWTA-DWSQIEEEYSPSRMSLHSV---VEAGL-CDRSLQIDYDEHVA 109

Query: 185 DLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKD 244
           +    +  I  L + +  +PF L + F  PH P    KE+       K+  P+  +IP +
Sbjct: 110 NTARQE--IYDLARSSDKRPFLLHVSFTHPHNPFVTTKEFWDLYNHQKIAMPEVSHIPYE 167

Query: 245 MPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV 304
                  PW+  R    IR+         +  +     R +Y+A   Y D+L+G LL  +
Sbjct: 168 ----GRDPWSQ-RYYMTIRQDEFD-----ITDEQLRNARHAYFAMTSYFDKLVGDLLDVL 217

Query: 305 ----DMQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEP--VE 358
                M  T + + SDHG  +GE G+W K++ F+ +++VP+I   P+L    V EP    
Sbjct: 218 KTTNQMDNTYVFVISDHGDMIGERGMWFKFNPFEGSVRVPMIGMGPRLSHGHV-EPALTT 276

Query: 359 LIDIFPTLVDL 369
           L D+ PT VD+
Sbjct: 277 LADLLPTFVDI 287


>UniRef50_A6DLX7 Cluster: Putative sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Putative sulfatase - Lentisphaera
           araneosa HTCC2155
          Length = 502

 Score = 77.4 bits (182), Expect = 8e-13
 Identities = 98/393 (24%), Positives = 167/393 (42%), Gaps = 46/393 (11%)

Query: 36  HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDR 95
           +  +  V  PN++ L   G  F   F    +C+PSR S +TG   ++      + Y  +R
Sbjct: 21  YAGNPNVKTPNLDDLANEGVEFEQGFCNNPICSPSRLSFITGLYTNN------HGYLGNR 74

Query: 96  SNG--QGNFTTIPQFFKEHGYDTYSVGK---VFHPGKSSNFTDDYPYSWSEYPYHPPTEM 150
           +N     N  T+   F+  GY T  VGK   +    K       Y          P T  
Sbjct: 75  NNDVTTPNPNTLSSLFRRFGYQTGLVGKSHMITGWDKEGFEYIRYTDMCDADDNDPHTCH 134

Query: 151 YKDAKVCRNKKTKKLERN-LICPVSVKRQPGQSLPDLQSLDY-----AIDFLKKRNGSKP 204
           Y D    R       E +      ++      SLP   S+++     +++FL+ R+  +P
Sbjct: 135 YFDYLAQRGLADHYEEGSPKEGQQTLDGSQPASLPYKHSIEHYTGNKSLEFLENRDQDRP 194

Query: 205 FFLAIGFHKPHIPLK-FPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRK-RDDI 262
           FFL + F +PH P+   P+++        ++ P++  +P+ +  +  + +    +   D 
Sbjct: 195 FFLKMSFQRPHDPITPAPEDF-------DMYNPEDIVLPESISDLFENKFVGKPQFMQDY 247

Query: 263 RRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV----DMQKTIIVLTSDHG 318
                 +P  V       +   SYYA    IDE IG ++ ++    +   TII  T+DHG
Sbjct: 248 VANPGDYPMCVADEAKLKRALASYYALITKIDEEIGRVIDHLKETGEYDNTIIFYTADHG 307

Query: 319 WSLGENGLWAK-YSNFDYALKVPLIFKSPKLIPTVV--HEPVELIDIFPTLVDLTKLSDE 375
              GE+GL+ K    ++   ++P + K P   PT V   E VE +D + TL DL  +  +
Sbjct: 308 DFAGEHGLFLKNLGIYESIHRIPFLLKWPG-GPTGVKNKELVESVDWYATLCDLCNI--Q 364

Query: 376 IPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEA 408
            P  +          +G+SLVP  +  + G +A
Sbjct: 365 APDNV----------DGRSLVPVAKGEAKGSDA 387


>UniRef50_A6UE90 Cluster: Sulfatase; n=1; Sinorhizobium medicae
           WSM419|Rep: Sulfatase - Sinorhizobium medicae WSM419
          Length = 489

 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 96/369 (26%), Positives = 154/369 (41%), Gaps = 57/369 (15%)

Query: 25  NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N+LFI  D           D  V  PNI+ L + G  F+NA+    +C PSR S+LT R 
Sbjct: 5   NVLFIFSDQHAQKVAGCYGDDVVRTPNIDRLAQEGVRFDNAYCPSPICTPSRMSMLTARW 64

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
           P           W +    + +  T      E GY    +G++   G       D  + +
Sbjct: 65  PHRQEC------WTNDDMLRSDVPTWLHRAGEAGYRPALIGRMHSIGP------DQLHGY 112

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQ-PGQSL---PDLQSLDYAIDF 195
           +E      T  +  A + R         N    VS+ +   G ++    D   +D A  +
Sbjct: 113 AERGIGDHTPNF--AGIARFPMGVLEGTNEPDSVSLTQSGAGMAIYQRKDQDVVDAAAAW 170

Query: 196 LKKRNGSK-----PFFLAIGFHKPHIPLKFPKE----YLKQMPISKVHRPKEPNIPKDMP 246
           L+ +  ++      F L +G   PH P    +E    Y  Q+P      P   ++P+D  
Sbjct: 171 LRDKGAARNAAGQQFCLTVGLMTPHAPYVVDREAFDHYHGQVP------PPRLDVPQDEH 224

Query: 247 LVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD- 305
              WH W     R D R +      G +      + R +Y+      DE+IG +L  +  
Sbjct: 225 --DWHRWW----RHD-RGI------GEVSDAVRDRARAAYWGLVQRTDEMIGQVLDALKE 271

Query: 306 ---MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT--VVHEPVELI 360
              M  T+IV  SDHG  +GE GLW K++ F+ ++K PL+ + P  IP      + V L+
Sbjct: 272 IGAMDDTLIVYASDHGDHVGERGLWWKHTFFEESVKFPLVMRLPGAIPAGESRDQVVNLV 331

Query: 361 DIFPTLVDL 369
           D+  T++++
Sbjct: 332 DLSQTMIEV 340


>UniRef50_Q4WBJ6 Cluster: Arylsulfatase, putative; n=4;
           Pezizomycotina|Rep: Arylsulfatase, putative -
           Aspergillus fumigatus (Sartorya fumigata)
          Length = 598

 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 60/201 (29%), Positives = 91/201 (45%), Gaps = 20/201 (9%)

Query: 22  TPKNILFILIDDLRHLSDKKVYLPNIN-FLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           T  N+LFI+ DD     +   + P I   +   G  F N F   +LC PSR SL TGR+ 
Sbjct: 34  TQPNVLFIMSDDQDLELNSPAFTPYIQKHIRDKGVEFTNHFVTTSLCCPSRVSLWTGRQA 93

Query: 81  DSLRLYDFYSYWRDRSN--GQG-NFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPY 137
            +  + D    W        QG N   +P + +E GY+TY  GK+ +   +SN+   +P 
Sbjct: 94  HNTNVTDVSPPWGGYPKFVSQGFNEAWLPVWLQEAGYNTYYTGKLMNGHTTSNYNSPFPK 153

Query: 138 SW--SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDF 195
            W  S++   P T  Y ++   RN++              K   GQ   D+ + + A+ F
Sbjct: 154 GWNGSDFLLDPYTYAYLNSTYQRNREPP------------KNYAGQYTTDVIT-EKALGF 200

Query: 196 LKKR-NGSKPFFLAIGFHKPH 215
           L    +  +PFFLA+    PH
Sbjct: 201 LNDALSSDRPFFLAVAPIAPH 221


>UniRef50_Q7NMX5 Cluster: Gll0640 protein; n=1; Gloeobacter
           violaceus|Rep: Gll0640 protein - Gloeobacter violaceus
          Length = 834

 Score = 76.6 bits (180), Expect = 1e-12
 Identities = 85/330 (25%), Positives = 147/330 (44%), Gaps = 37/330 (11%)

Query: 23  PKNILFILIDDLRHLSDKKVYLPNINF-LGKTGATFNNAFAQQALCAPSRNSLLTGRRPD 81
           P N++ I+ DD     +   Y+P +   L   G TF NAFA Q+LC PSR ++LTGR P 
Sbjct: 35  PPNVVLIVTDD--QAWNTLAYMPKLQSQLASQGVTFTNAFAGQSLCCPSRATILTGRYPH 92

Query: 82  SLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSE 141
           +  +    + +   +    + +T+P + +E GY T   GK F+    S F    P  W E
Sbjct: 93  NHGVLGNDAPF-GGALAFYDASTLPVWLQESGYRTGLFGKYFNGYSYSAFYT--PPGWDE 149

Query: 142 YPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNG 201
           +        Y + ++  N   +   R+         +   S   L     A+ F+     
Sbjct: 150 WQTFQLAGYY-NYRINANGTIEDYGRS---------ESNYSTDVL--TQKAVAFITNSAA 197

Query: 202 S-KPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRD 260
           S KPFFL +    PH P           P  + H  +  +IP   P  +++    + K  
Sbjct: 198 SDKPFFLFLAPFAPHAP---------YTPAPR-HAGRYADIPPWRP-PNYNEQDVLDKPT 246

Query: 261 DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSD 316
            +++L    P     T +  K RQ+Y    L +D+ +  +L  ++     + T+++ TSD
Sbjct: 247 WVQKLRPASP--QTQTDYD-KERQAYLEMLLAVDDGVESILQALESTGQRENTLVIFTSD 303

Query: 317 HGWSLGENGLWAKYSNFDYALKVPLIFKSP 346
           +G + GE+  W K  +++ +L+VP++   P
Sbjct: 304 NGLTWGEHRWWEKGCSYEESLRVPMVVSFP 333


>UniRef50_Q8IWU6 Cluster: Extracellular sulfatase Sulf-1 precursor;
           n=28; Euteleostomi|Rep: Extracellular sulfatase Sulf-1
           precursor - Homo sapiens (Human)
          Length = 871

 Score = 76.6 bits (180), Expect = 1e-12
 Identities = 83/352 (23%), Positives = 145/352 (41%), Gaps = 25/352 (7%)

Query: 25  NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
           NI+ +L DD    L   +V       +   GATF NAF    +C PSR+S+LTG+   + 
Sbjct: 44  NIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNH 103

Query: 84  RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
            +Y         S        T   +    GY T   GK  +    S      P  W E+
Sbjct: 104 NVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYI----PPGWREW 159

Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGS 202
                   + +  VCRN   +K            +     L   +S++Y     K+    
Sbjct: 160 LGLIKNSRFYNYTVCRNGIKEKHG------FDYAKDYFTDLITNESINY-FKMSKRMYPH 212

Query: 203 KPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDI 262
           +P  + I    PH P     ++ K  P +  H     N   +M     H W  ++    +
Sbjct: 213 RPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDK---H-WI-MQYTGPM 267

Query: 263 RRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWSLG 322
             +++ F   ++  K      Q+  +    ++ L  +L+   +++ T I+ T+DHG+ +G
Sbjct: 268 LPIHMEFT-NILQRKRL----QTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIG 322

Query: 323 ENGL-WAKYSNFDYALKVPLIFKSPKLIP-TVVHEPVELIDIFPTLVDLTKL 372
           + GL   K   +D+ ++VP   + P + P ++V + V  ID+ PT++D+  L
Sbjct: 323 QFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNIDLAPTILDIAGL 374


>UniRef50_A5P718 Cluster: Calcium-binding protein; n=1;
           Erythrobacter sp. SD-21|Rep: Calcium-binding protein -
           Erythrobacter sp. SD-21
          Length = 1015

 Score = 75.8 bits (178), Expect = 3e-12
 Identities = 47/124 (37%), Positives = 71/124 (57%), Gaps = 18/124 (14%)

Query: 284 QSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKV 339
           Q+Y AA  Y D L+  LL  +D    ++ T +VL +DHG+ LG+   W K++ ++ A + 
Sbjct: 2   QAYLAAISYADHLLRQLLDQLDESGLIESTTVVLWTDHGYHLGDKNQWGKFTLWEDAARA 61

Query: 340 PLIFKSPKLIP--TVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVP 397
           P +   P       +V + VEL+D+ PTL+DLT L+  IP+ L          +G+SLVP
Sbjct: 62  PFVIAQPGTADDGQLVDQVVELVDLMPTLLDLTGLA--IPQGL----------DGRSLVP 109

Query: 398 FIEN 401
           FIEN
Sbjct: 110 FIEN 113


>UniRef50_A4AQQ7 Cluster: N-acetylgalactosamine 6-sulfatase; n=4;
           Bacteria|Rep: N-acetylgalactosamine 6-sulfatase -
           Flavobacteriales bacterium HTCC2170
          Length = 596

 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 66/226 (29%), Positives = 110/226 (48%), Gaps = 35/226 (15%)

Query: 18  SDVETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRN 72
           ++++T  N++ I+ DD     L    +  +  PNI+ + K GA+F N F  Q +C+P+R 
Sbjct: 31  NEIQTKPNVVLIMTDDQGWGDLSFNGNTNLSTPNIDAIAKNGASFQN-FYVQPVCSPTRA 89

Query: 73  SLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFT 132
            LLTG+    L +Y   S   +R N +   TTI + FK+ GY T + GK +H G      
Sbjct: 90  ELLTGKYAARLGVYS-TSTGGERFNSKE--TTIAEIFKKAGYKTTAYGK-WHSG------ 139

Query: 133 DDYPYSWSEYPYHPPTEMYKD-----AKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQ 187
                   + PYHP +  + D     +    N  +  LE N      + +  G  + DL 
Sbjct: 140 -------MQPPYHPNSRGFDDYYGFTSGHWGNYFSPMLEHN----GEIVKGEGFLVDDL- 187

Query: 188 SLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKV 233
             +  +DF+ + N + PFFL + ++ PH P++ P EY ++    K+
Sbjct: 188 -TNKGLDFITE-NKNNPFFLYLPYNTPHSPMQVPNEYWERFEKKKL 231


>UniRef50_A3I0S5 Cluster: Putative sulfatase yidJ; n=1; Algoriphagus
           sp. PR1|Rep: Putative sulfatase yidJ - Algoriphagus sp.
           PR1
          Length = 491

 Score = 74.9 bits (176), Expect = 4e-12
 Identities = 67/233 (28%), Positives = 100/233 (42%), Gaps = 19/233 (8%)

Query: 18  SDVETPKNILFILIDDLR-----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRN 72
           S+V+TP NI+F+L D  R     +  + ++  PN+N L      F NA    A+CAP R 
Sbjct: 32  SNVQTPPNIVFVLADQWRAQEVGYAGNDQIITPNLNKLATESLIFENAVTTMAVCAPWRA 91

Query: 73  SLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFT 132
           S LTG+ P  L    FY+   D+      + T  + +KE GY T  +GK +H    +   
Sbjct: 92  SFLTGQYP--LTHGVFYN---DKPLPNEAY-TFAEIYKEAGYQTGYIGK-WHLNGHARGA 144

Query: 133 DDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYA 192
           D  P+S  + P         D    R + T     +       K+   +        D A
Sbjct: 145 D--PFSARDQPVPKDRRQGFDYWKVR-EVTHNYNNSFYFDEEDKKHVWEGYDVFPQTDSA 201

Query: 193 IDFLKKRNGSKPFFLAIGFHKPHIP-LKFPKEYLKQMPISKVHRPKEPNIPKD 244
           I ++ K N  KPF L + +  PH P    PKEY        +     PN+P++
Sbjct: 202 ISYISK-NKEKPFVLMLSYGPPHDPYFSAPKEYQDLYDAGTL--KLRPNVPEE 251



 Score = 68.1 bits (159), Expect = 5e-10
 Identities = 45/120 (37%), Positives = 64/120 (53%), Gaps = 7/120 (5%)

Query: 281 KIRQSYYAAALYIDELIGILLSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYA 336
           ++   YYA A  ID+ IG LL  ++       TI V TS+HG  L   G+  K   +D A
Sbjct: 258 RVLAGYYAHATAIDKAIGDLLEGIEKAGVADNTIFVFTSEHGDMLMSRGVVKKQRPWDEA 317

Query: 337 LKVPLIFKSP-KLIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSL 395
           +KVP++ + P KL    V +P+   DI PTL+ L+ +   IPK +  KD S+    GK L
Sbjct: 318 IKVPMLIRYPGKLESRRVLDPIGTPDILPTLLGLSDI--PIPKSIEGKDFSKNLLSGKDL 375


>UniRef50_UPI00015B4E43 Cluster: PREDICTED: similar to CG6725-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG6725-PA - Nasonia vitripennis
          Length = 1301

 Score = 74.1 bits (174), Expect = 8e-12
 Identities = 100/381 (26%), Positives = 163/381 (42%), Gaps = 42/381 (11%)

Query: 25  NILFILIDDLRHLSDKKVYLPN-INFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
           NI+ IL DD         ++PN +  +   GA   +A+    +C PSR+SLLTGR   + 
Sbjct: 14  NIVLILTDDQDVELGSLNFMPNTLKRIRDEGADLRHAYVTTPMCCPSRSSLLTGRYVHNH 73

Query: 84  RLY---DFYS--YWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
            ++   D  S   W+ R +    F T   +    GY T   GK  +    S      P  
Sbjct: 74  EVFTNNDNCSSPQWQ-RDHEPHTFAT---YLSNAGYRTGYFGKYLNKYNGSYI----PPG 125

Query: 139 WSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK- 197
           W E+        Y +  V  N   KK++                 PDL + D ++ FL+ 
Sbjct: 126 WREWGGLIMNSRYYNYSV--NMNGKKIKHGF-------EYNKDYYPDLIAND-SVAFLRQ 175

Query: 198 -KRN-GSKPFFLAIGFHKPHIPLKFPKEYLKQM-PISKVHRPKEPNIPKDMPLVSWHPWT 254
            K N   KP  L   F  PH P     +Y      ++  H P     P   P   W    
Sbjct: 176 SKHNFARKPVMLVASFPAPHGPEDSAPQYSDMFFNVTTHHTPAYDYAPN--PDKQWI--- 230

Query: 255 DVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLT 314
            ++    ++ ++  F   ++ TK  L+  QS  AA   ++ +   L S  ++  T I+ T
Sbjct: 231 -LQVTQKMQPIHKEFT-DLLMTK-RLQTLQSVDAA---VERIYQELKSLGELDNTYIIYT 284

Query: 315 SDHGWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIP-TVVHEPVELIDIFPTLVDLTKL 372
           SDHG+ LG+ GL   K   F++ ++VP + + P + P +VV + V  ID+ PT +D+  +
Sbjct: 285 SDHGYHLGQFGLIKGKSFPFEFDVRVPFLVRGPGIAPGSVVDDIVLNIDLAPTFLDIAGV 344

Query: 373 SDEIPKCLNHKDTSQLCFEGK 393
            + +P  ++ +   +L    K
Sbjct: 345 -EPLPPRMDGRSFKKLFLNNK 364


>UniRef50_Q7UGD6 Cluster: Mucin-desulfating sulfatase; n=1;
           Pirellula sp.|Rep: Mucin-desulfating sulfatase -
           Rhodopirellula baltica
          Length = 578

 Score = 74.1 bits (174), Expect = 8e-12
 Identities = 104/401 (25%), Positives = 165/401 (41%), Gaps = 40/401 (9%)

Query: 25  NILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N LF+L DD  +       ++    PNI+ L + G  F+ A+   A+C PSR S+   + 
Sbjct: 53  NFLFVLTDDQSYGMMGCDGNELTRTPNIDQLAREGIFFDRAYVTSAICTPSRISIFLSQY 112

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
            +     +F S             + P   +++GY T  VGK   P     +        
Sbjct: 113 -ERKHGVNFNSGTSVAPEAWAK--SYPVVMRDNGYYTGYVGKNHAPIGKDGYNSGLMEES 169

Query: 140 SEYPY--HPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
            +Y Y  H     Y  A    +K  +  E +    + V       L     LD A+ FL+
Sbjct: 170 FDYFYAGHGHIRFYPKAV---HKIFEGAEYDTQVEI-VNEGAEDFLSYEHRLDGAVRFLE 225

Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMP--ISKVHRPKEPNIPKDMPLVSWHPWTD 255
           +R   KPF L+I  + PH       +  +        ++R  E  +PK   +      T 
Sbjct: 226 ERPADKPFCLSICLNLPHSAGTGSMQQRESDDDIYKSLYRDIEIPLPKHY-VAKDDIKTP 284

Query: 256 VRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALY-IDELIGILLSYVDMQ----KTI 310
               D +R  +    +  + T   LK R      +L  ID LIG L + ++ +     TI
Sbjct: 285 RLPADVLRASDRQTGYNFVDTPELLKERIIRQMQSLTGIDRLIGNLRTKLETEGVDDNTI 344

Query: 311 IVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVV-----HEPVELIDIFPT 365
           I+  SDHG  +G++GL  K   ++    VPLI   P+L PTV+     +E V+ IDI  T
Sbjct: 345 IIFCSDHGLFMGQHGLGGKALCYEQTTHVPLIVYDPEL-PTVLKGARCNELVQTIDIAAT 403

Query: 366 LVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGL 406
           ++DL  +  E P            F+GKS+ P +  +   +
Sbjct: 404 MLDLADI--ETP----------ATFQGKSMRPLLSGDGGAI 432


>UniRef50_A3TPK9 Cluster: Probable phosphonate monoester hydrolase;
           n=2; Micrococcineae|Rep: Probable phosphonate monoester
           hydrolase - Janibacter sp. HTCC2649
          Length = 508

 Score = 74.1 bits (174), Expect = 8e-12
 Identities = 89/380 (23%), Positives = 156/380 (41%), Gaps = 51/380 (13%)

Query: 25  NILFILIDDLRH--LSDK---KVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N++ I +D+ R   LS      V  P+++ L   G  F+ A++    C P+R +L TG+ 
Sbjct: 14  NVVLICVDEWRGDALSSAGHPHVQTPHLDELAARGTRFDRAYSATPTCVPARVALFTGQS 73

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK--VFHPGKSSNFTD---- 133
            ++   +    Y       Q +  T+P  F++ GY T ++GK  VF       F D    
Sbjct: 74  QEA---HGRVGYVEGVPFEQAHPVTLPGEFRKAGYQTQAIGKMHVFPERSRVGFDDVVLH 130

Query: 134 DYPYSWSEYPYHPPTEMYKDAKVCRNKK------TKKLERNLICPVSVKR---QPGQSLP 184
           D     +   +    E + D      ++          +  + C   V R   +P  + P
Sbjct: 131 DGFLHHARRGHRRQFEFFDDYVPWLRRQPGLDADADYFDHGVNCNSIVARPWDKPESAHP 190

Query: 185 DLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKD 244
                  A+++L +R+ + PFFL + FH+PH P   P+    Q     +  P     P +
Sbjct: 191 THWLGTQAVNWLPRRDPTVPFFLYLSFHRPHPPYDPPQWAFDQY----LALP-----PYE 241

Query: 245 MPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV 304
             L  W    D  + D   + +I    G +P     + R  YY     ID  +   +  +
Sbjct: 242 RELGDWEDEWDEFREDGNHQASI----GDLPDAMVHRARAGYYGLMAQIDLQVNRFIESL 297

Query: 305 D----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIF-----------KSPKLI 349
                ++ T++  TSDHG  +G++ ++ K   ++ + +VP I            +     
Sbjct: 298 GELGLLENTVVAFTSDHGEMMGDHRMFKKAVPYEGSARVPFIIADAPARQGDGVEGGTAR 357

Query: 350 PTVVHEPVELIDIFPTLVDL 369
             VV   VEL D+ PTL++L
Sbjct: 358 DAVVSHVVELRDLMPTLLEL 377


>UniRef50_A6DG38 Cluster: N-acetylglucosamine-6-sulfatase; n=1;
           Lentisphaera araneosa HTCC2155|Rep:
           N-acetylglucosamine-6-sulfatase - Lentisphaera araneosa
           HTCC2155
          Length = 498

 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 96/391 (24%), Positives = 168/391 (42%), Gaps = 41/391 (10%)

Query: 3   YVVNIILLNGDRVLTSDVETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATF 57
           Y V+ IL      LT+ VE   NI+ I  DD     L    +  +  P ++ L   G  F
Sbjct: 5   YKVSCILFGVIASLTA-VEQRPNIILIFSDDHAKKALSCYGNTGIKTPALDRLADGGMRF 63

Query: 58  NNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTY 117
           N+A    + C PSR + LTG+              R   +  G+  T P+  ++ GY+T 
Sbjct: 64  NHALVTNSFCTPSRATALTGKYSHK------NGVTRLNQSFDGSQQTFPKLLQKAGYETS 117

Query: 118 SVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKR 177
             GK     + + F           P++P     +   V  + + +K           + 
Sbjct: 118 LFGKWHLLSQPTGFDYYCVQKMQGMPFNPRVFEPQHGWVPWSPQDRKSYMK-----GGRV 172

Query: 178 QPGQSLPDLQSLDYAIDFLKKR-NGSKPFFLAIGF---HKPHIPLKFPKEYLKQMPI--- 230
             G +  D+ + + AI+++K R N +KPF L +     H P+ P    ++YLK + I   
Sbjct: 173 IKGYN-NDVITTE-AINWIKNRENKNKPFCLLLHPKPPHAPYTPATRDEDYLKDVTIPEP 230

Query: 231 SKVHRPKEPNIPKDMP-------LVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIR 283
           + +H   +   P  +        ++    +  +R R  I + N       + +K   +  
Sbjct: 231 ANLHDDYKGRTPHAIAGKMTANRIILNPAFKSMRAR--IEKENPNISERELTSKMYQEYI 288

Query: 284 QSYYAAALYIDELIGILLSYVD---MQK-TIIVLTSDHGWSLGENGLWAKYSNFDYALKV 339
           + YY     +D+ +G +L Y+    ++K TI++ TSD G+SLGE+G + K   ++  L  
Sbjct: 289 KGYYRLVKSVDDNVGRVLDYLKESGLEKNTIVIYTSDQGFSLGEHGFYNKQWMYEEPLHA 348

Query: 340 PLIFKSPKLIPT-VVHEPV-ELIDIFPTLVD 368
           P + K P  +    VH  +   +DI PT++D
Sbjct: 349 PFLVKFPGTVKAGQVHNSMTSHVDIAPTILD 379


>UniRef50_A4FI25 Cluster: Sulfatase; n=3; Actinomycetales|Rep:
           Sulfatase - Saccharopolyspora erythraea (strain NRRL
           23338)
          Length = 502

 Score = 72.9 bits (171), Expect = 2e-11
 Identities = 96/380 (25%), Positives = 157/380 (41%), Gaps = 54/380 (14%)

Query: 25  NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NILF++ D  R        + +   PN++ L  TG  F+  +   A+C P+R SLLTG+ 
Sbjct: 5   NILFLMTDQHRADTLGAYGNPRAATPNLDELASTGTRFDRWYTPTAICTPARASLLTGKA 64

Query: 80  PDSLRLYDFY----SYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY 135
           P   +L   +     Y  D  +GQ  F+   +  +++GY+   +GK +H G +     D+
Sbjct: 65  PFRHKLLANHERNVGYIEDLPDGQFTFS---EALRDNGYNCGLIGK-WHVG-TDRSAGDF 119

Query: 136 PYSWSEYP-YHPPTE--------------MYKDAKVCRNKKTKKLERNLICPVSVKRQPG 180
            +   + P +H P E               Y+ +   R         NL+   +   QP 
Sbjct: 120 GFDGPDLPGWHNPVEHPDYLAYLAGNGFPPYEISDRIRGTLPNGGPGNLL--AARLHQPV 177

Query: 181 QSLPDLQSLDYAIDFLKK-----RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHR 235
           ++  +      AI+ +++         KPFFLA+ F  PH+P   P  Y           
Sbjct: 178 EATFEHYLATRAIEMMERYAADASERDKPFFLALHFFGPHLPYIIPDSYFDLFD------ 231

Query: 236 PKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDE 295
                 P D+PL      T   K    R  +  + F  MP + T K+   Y+     ID 
Sbjct: 232 ------PADVPLPRSVAETFHGKPPVQRNYSAHWTFDTMPIETTRKLIAVYWGYVALIDH 285

Query: 296 LIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAK-YSNFDYALKVPLIFKSPKLIP 350
            IG +++ +       +T +  T DHG   G + L  K  + ++   + P I + P    
Sbjct: 286 EIGRVMAAMRRLGLADETAVFFTCDHGEFTGAHRLHDKGPAMYEDIYRTPGIVRVPGGPG 345

Query: 351 TVVH-EPVELIDIFPTLVDL 369
            VV  E V L+D   T++DL
Sbjct: 346 GVVRSEFVSLLDCTATILDL 365


>UniRef50_Q15NY5 Cluster: Sulfatase precursor; n=1;
           Pseudoalteromonas atlantica T6c|Rep: Sulfatase precursor
           - Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 486

 Score = 72.5 bits (170), Expect = 2e-11
 Identities = 96/385 (24%), Positives = 163/385 (42%), Gaps = 57/385 (14%)

Query: 5   VNIILLNGDRVLTSDVETPKNILFILIDDLRHLS----DKKVYLPNINFLGKTGATFNNA 60
           ++++     +V  +  ++  NI+ I+ DD    +    +K +  PNI++L   G  FNNA
Sbjct: 9   ISVLFFLATQVQAAQEKSKPNIIVIMTDDQGQWTLGAYEKHMKTPNIDYLADQGVLFNNA 68

Query: 61  FAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWR--DRSNGQGNFTTIPQFFKEHGYDTYS 118
                +C+ +R S  TG+ P    +YDF S     D    QG  T + +  ++ GY T  
Sbjct: 69  MTSAPVCSAARASFHTGKMPSQHGVYDFLSEGNGFDDKWLQGE-TFLGERMQQSGYRTGL 127

Query: 119 VGK--VFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVK 176
            GK  V  P        D   S   +      +     KV  +K  +  E          
Sbjct: 128 FGKWHVKEPSLEPAGGFDRWISHDAFKAGWRNQYQHRGKVAFSKDGEAFEHT-------- 179

Query: 177 RQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRP 236
              G     L   + AI+F+ + +  KPFF+ I + +PH    FP E L +  +S+ +RP
Sbjct: 180 ---GVQARFL--TEKAIEFIDE-STDKPFFININYVEPH----FPFEGLPERLVSQ-YRP 228

Query: 237 KEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDEL 296
               + +D    S               L +      +P     K+ Q Y AA   ID+ 
Sbjct: 229 VARKLLRDGGNSS---------------LALASKDTAVPKDHEEKLSQ-YLAAISLIDDQ 272

Query: 297 IGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAK------YSNFDYALKVPLIFKSP 346
           +G ++  ++    +  TII   SDHG  +G+ GL+ K      Y+ ++  +++P I   P
Sbjct: 273 VGQIMDALEGRGLLDNTIIAFVSDHGMLMGQYGLYGKTNASFPYNFYEETVRIPFIIYGP 332

Query: 347 KLI---PTVVHEPVELIDIFPTLVD 368
           K +        E V+L+D+  T++D
Sbjct: 333 KSLVQGRQSRDEFVDLLDLHNTILD 357


>UniRef50_A6DFN4 Cluster: Arylsulfatase; n=1; Lentisphaera araneosa
           HTCC2155|Rep: Arylsulfatase - Lentisphaera araneosa
           HTCC2155
          Length = 481

 Score = 72.5 bits (170), Expect = 2e-11
 Identities = 70/238 (29%), Positives = 110/238 (46%), Gaps = 28/238 (11%)

Query: 22  TPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           TP N+++IL DDL +        +K+  P+I+ L K G  F   ++   +CAPSR  LL+
Sbjct: 19  TP-NVIYILADDLGYGELGCYGQEKIKTPHIDALAKEGMRFTRHYSGAPVCAPSRGVLLS 77

Query: 77  GRRPDSLRLYDFYSYWRDRSNGQGNF----TTIPQFFKEHGYDTYSVGK--VFHPGKSSN 130
           G++     + +   +   +  GQ        T+ Q FK+ GY T + GK  + +PG SS+
Sbjct: 78  GQQLSKAYIRNNREH---KPEGQEPIPEPGMTLAQIFKDKGYATGAFGKWGLGYPGSSSD 134

Query: 131 -----FTDDYPYSWSE--YPYHPPTEMYKDAKVCRNKKTKKLE-RNLICPVSVKRQ--PG 180
                F   Y Y+     + ++PP     D  +  N+K      R  + P     Q    
Sbjct: 135 PKALGFDTFYGYNCQRVAHSFYPPHMWSNDKNITINEKPVPGHWRKAVGPDFDFSQFYAE 194

Query: 181 QSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKE 238
              PDL  LD A+ F+K  N  KPFF  + F +PH+ +  P  ++   P  +   PKE
Sbjct: 195 NYAPDL-ILDEALKFIKD-NKDKPFFAYLPFVEPHLAMHPPHSWVDSYP-KEWDSPKE 249


>UniRef50_A6CBI6 Cluster: Putative uncharacterized protein; n=1;
           Planctomyces maris DSM 8797|Rep: Putative
           uncharacterized protein - Planctomyces maris DSM 8797
          Length = 599

 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 69/230 (30%), Positives = 108/230 (46%), Gaps = 30/230 (13%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGA 55
           +++V+ +IL  G  +  +  E P N+L I+ DD     +R   +  +  P  + L   GA
Sbjct: 11  LLFVLTLILSRGSFLQAA--ERP-NVLLIMTDDQGWGDVRSHDNPLIETPQQDLLASQGA 67

Query: 56  TFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYD 115
            F   F    +CAP+R+SLLTGR   SLR    +   R   N +   TTI + FK  GY 
Sbjct: 68  RFER-FYVSPVCAPTRSSLLTGRY--SLRT-GVHGVTRGFENMRAEETTIAEMFKAAGYK 123

Query: 116 TYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDA-KVCRNKKTKKLERNLICPVS 174
           T + GK +H G+              YP HP  + + +    C     +  + NL     
Sbjct: 124 TGAFGK-WHNGR-------------HYPMHPNGQGFDEFFGFCGGHWNRYFDTNLEHNKQ 169

Query: 175 VKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEY 224
             +  G  + D+ + D AIDF+K+ N  +PFF  + ++ PH P   P++Y
Sbjct: 170 PVKTEGY-ITDVLT-DRAIDFIKQ-NKDQPFFCYVPYNAPHSPWIVPEKY 216



 Score = 41.1 bits (92), Expect = 0.067
 Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 19/127 (14%)

Query: 287 YAAALYIDELIGILLSYVDMQK----TIIVLTSDHGWSLGE---NGLWAKYSNFDYALKV 339
           YA    +D+ +G L+  +D  K    TI++  +D+G +      N    K S  +  ++V
Sbjct: 233 YAMVECVDDNLGRLMQTLDDLKLSDNTIVLFLTDNGPNSNRYNGNMRGRKGSIHEGGIRV 292

Query: 340 PLIFKSPKLIP--TVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVP 397
           PL  + P  I   TVV      IDI PTL++L  +          ++T+    +GKSLVP
Sbjct: 293 PLFVRYPGKIKAGTVVKPIAAHIDILPTLLELCSV----------ENTADQPLDGKSLVP 342

Query: 398 FIENNSN 404
            + N SN
Sbjct: 343 LLTNKSN 349


>UniRef50_Q5LKJ1 Cluster: Phosphonate monoester hydrolase, putative;
           n=4; Rhodobacteraceae|Rep: Phosphonate monoester
           hydrolase, putative - Silicibacter pomeroyi
          Length = 509

 Score = 70.9 bits (166), Expect = 7e-11
 Identities = 54/184 (29%), Positives = 88/184 (47%), Gaps = 12/184 (6%)

Query: 205 FFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKR-DDIR 263
           +F  + + +PH PL  P  Y      +K+  P    +P      + HP+     R     
Sbjct: 204 WFAHLTYIRPHPPLVAPAPYNTMYDPAKL--PLPARLPGRDDETAEHPFFGPATRYSSPA 261

Query: 264 RLNITFPFGVMPTKWTLK-IRQSYYAAALYIDELIGILLSYV----DMQKTIIVLTSDHG 318
              + FP  + PT  T++ +R  Y   A  +D  IG +++++        T+IV+T+DHG
Sbjct: 262 SFVLGFP-DLEPTDETIQTLRAVYLGLATEVDTHIGRVIAHLKETGQYDDTLIVVTADHG 320

Query: 319 WSLGENGLWAKYSNFDYALKVPLIFKSPKLIP-TVVHEPVELIDIFPTLVDLTKLSDEIP 377
             LG+   W K + +D A   PLI ++P   P  VV  P E ID+ PT++D   +  EIP
Sbjct: 321 EMLGDRHSWGKMTVYDAAYHTPLIIRAPGCKPGHVVEAPTESIDLMPTILDW--VGQEIP 378

Query: 378 KCLN 381
             ++
Sbjct: 379 NAVD 382



 Score = 37.9 bits (84), Expect = 0.63
 Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 7/60 (11%)

Query: 25 NILFILIDDLRH------LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
          N+LFI+ID LR       L+D  V LP++  L +   +F   ++    C PSR S+LTG+
Sbjct: 6  NVLFIIIDQLRADCLWGALADH-VELPHLRALAQDAVSFRRHYSVTNPCGPSRASILTGQ 64


>UniRef50_Q15XH3 Cluster: Sulfatase precursor; n=1;
           Pseudoalteromonas atlantica T6c|Rep: Sulfatase precursor
           - Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 500

 Score = 70.9 bits (166), Expect = 7e-11
 Identities = 61/219 (27%), Positives = 102/219 (46%), Gaps = 28/219 (12%)

Query: 25  NILFILIDDLRHLS-----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NILF+L DDL +          +  PN++ L K G TF+ A+     C PSR +++TGR 
Sbjct: 41  NILFVLADDLGYNDVGFNGSTDIKTPNLDGLAKNGMTFDAAYVAHPFCGPSRAAIMTGRY 100

Query: 80  PDSLRLYDFYSYWRDRSN--GQGNFTTIPQFFKEHGYDTYSVGK-------VFHPGKSSN 130
           P  +     ++   D SN     +   I Q  K  GY T ++GK        +HP K   
Sbjct: 101 PHKIGAQ--FNLPEDNSNVGVSADELFIAQTMKSAGYFTGAMGKWHLGEASEYHPNK-HG 157

Query: 131 FTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLD 190
           F + Y +    + Y P  E ++ A    NK+  +   N+   ++     G+ + + + + 
Sbjct: 158 FDEFYGFLGGGHNYFP--EQFEAA---YNKRVAQGMTNINMYLTPLEHNGKEVRETEYIT 212

Query: 191 -----YAIDFLKKRNG-SKPFFLAIGFHKPHIPLKFPKE 223
                 A++F+ K     KPFFL + ++ PH+PL+  +E
Sbjct: 213 DGLSREAVNFVDKAAAKKKPFFLYLAYNAPHVPLQAKEE 251


>UniRef50_A6DMZ1 Cluster: Sulfatase; n=5; Lentisphaera araneosa
           HTCC2155|Rep: Sulfatase - Lentisphaera araneosa HTCC2155
          Length = 514

 Score = 70.9 bits (166), Expect = 7e-11
 Identities = 87/352 (24%), Positives = 149/352 (42%), Gaps = 55/352 (15%)

Query: 45  PNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTT 104
           PNI+ L K G  F  A+   ++CAPSR +LLTG+      L+      +   + Q  F  
Sbjct: 53  PNIDRLAKEGMIFKRAYVGNSICAPSRATLLTGKHS---HLHGKVDNAKGFDHNQQQFQK 109

Query: 105 IPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKK 164
           + Q   + GY T  +GK+  PGK   F  DY   W   P                 + K 
Sbjct: 110 LLQ---KGGYQTAMIGKIHLPGKMQGF--DY---WEVLP----------------GQGKY 145

Query: 165 LERNLICPVSVKRQPGQSLPDLQSLDYAIDFL-KKRNGSKPFFLAIGFHKPHIPLKFPKE 223
            +   +        PG+   D+ +   A++++  +R+ SKPF L + F  PH   +    
Sbjct: 146 WDPEFVTETGKTIYPGEHSSDVIT-RRALNWMNNERDKSKPFMLMVHFKAPHRSWQPTTR 204

Query: 224 YLKQMPISKVHRP----------------KEPNIPKDMPLVSWHPWTDVRKRDDIRRLNI 267
           + K+        P                ++ NI   M +V         +++ +++  +
Sbjct: 205 WKKKFSTMTFPEPDTLFDDYQGRGTAAKYQDMNIEHSMNMVGDLKSNQSPRKEFLKKNAL 264

Query: 268 TFPFGVMPTKWTLKI-RQSYYAAALYIDELIGILLSYVDM----QKTIIVLTSDHGWSLG 322
           T   G    KW  ++  + Y A    +DE IG +L  +      + TI++ +SD G+ LG
Sbjct: 265 T---GKALVKWKYQMYMRDYLACIAGVDENIGKILDQLAESGLDKNTIVMYSSDQGFYLG 321

Query: 323 ENGLWAKYSNFDYALKVPLIFKSPKLI--PTVVHEPVELIDIFPTLVDLTKL 372
           E+G + K   ++ + + PL+ + P +I   T   + V+ ID   T +DL  L
Sbjct: 322 EHGWFDKRFMYEESYRTPLLARWPGVIKAKTRNEDLVQNIDFAETFLDLAGL 373


>UniRef50_Q8IWU5 Cluster: Extracellular sulfatase Sulf-2 precursor;
           n=52; Eumetazoa|Rep: Extracellular sulfatase Sulf-2
           precursor - Homo sapiens (Human)
          Length = 870

 Score = 70.9 bits (166), Expect = 7e-11
 Identities = 86/370 (23%), Positives = 148/370 (40%), Gaps = 31/370 (8%)

Query: 25  NILFILIDDLR-HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
           NI+ +L DD    L   +V       + + GA F NAF    +C PSR+S+LTG+   + 
Sbjct: 45  NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNH 104

Query: 84  RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
             Y         S   Q    T   +    GY T   GK  +    S      P  W E+
Sbjct: 105 NTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYV----PPGWKEW 160

Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL--KKRN 200
                   + +  +CRN   +K   +              L DL + D    F   KK  
Sbjct: 161 VGLLKNSRFYNYTLCRNGVKEKHGSDY---------SKDYLTDLITNDSVSFFRTSKKMY 211

Query: 201 GSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRD 260
             +P  + I    PH P     +Y +  P +  H     N   + P   W     +R   
Sbjct: 212 PHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPN-PDKHWI----MRYTG 266

Query: 261 DIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSDHGWS 320
            ++ +++ F           K  Q+  +    ++ +  +L+   ++  T IV T+DHG+ 
Sbjct: 267 PMKPIHMEFT-----NMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 321

Query: 321 LGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEPVEL-IDIFPTLVDLTKLSDEIPK 378
           +G+ GL   K   +++ ++VP   + P +    ++  + L ID+ PT++D+  L  +IP 
Sbjct: 322 IGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGL--DIPA 379

Query: 379 CLNHKDTSQL 388
            ++ K   +L
Sbjct: 380 DMDGKSILKL 389


>UniRef50_O43113 Cluster: Arylsulfatase; n=3; Sordariales|Rep:
           Arylsulfatase - Neurospora crassa
          Length = 639

 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 60/199 (30%), Positives = 90/199 (45%), Gaps = 20/199 (10%)

Query: 25  NILFILIDDLRHLSDKKVYLPNIN-FLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
           NI+FIL DD         YLP +  +L   G T+   +   A+C P+R SL TG++  + 
Sbjct: 46  NIVFILTDDQDLHLQSLDYLPLLKKYLADEGTTYKRHYCTTAICCPARVSLWTGKQAHNT 105

Query: 84  RLYD----FYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
            + D    +  Y +  S G  N   +P + ++ GYDTY  GK+F+     N+   Y   W
Sbjct: 106 NVTDVSPPYGGYPKFISQGF-NEAYLPVWLQKAGYDTYYTGKLFNAHTVDNYDSPYIAGW 164

Query: 140 --SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYA-IDFL 196
             S++   P T  Y +A   RN+           P+S + Q   S+  L    Y  +D  
Sbjct: 165 NGSDFLLDPYTYSYLNATFQRNRDP---------PISYEGQ--YSVDVLAEKAYGFLDEA 213

Query: 197 KKRNGSKPFFLAIGFHKPH 215
            K   ++PFFL I    PH
Sbjct: 214 AKNVHNRPFFLGIAPIAPH 232


>UniRef50_A2TWV5 Cluster: N-acetylglucosamine-6-sulfatase; n=1;
           Polaribacter dokdonensis MED152|Rep:
           N-acetylglucosamine-6-sulfatase - Polaribacter
           dokdonensis MED152
          Length = 542

 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 65/224 (29%), Positives = 106/224 (47%), Gaps = 42/224 (18%)

Query: 284 QSYYAAALYIDELIGILLSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKV 339
           + Y      +D  IG +L Y+D     + T+++ TSD G+ LGE+G + K   ++ + + 
Sbjct: 326 EDYLGVIKSVDRNIGRVLDYLDKNNLAKNTMVIYTSDQGFFLGEHGWFDKRFMYEESFRT 385

Query: 340 PLIFKSP-KLIP-TVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVP 397
           PL+ K P K+ P ++ ++ V+ ID  PT++D+ ++  +IPK +          +GKSLVP
Sbjct: 386 PLLIKFPNKIKPKSINYDLVQNIDFAPTILDVARV--DIPKEM----------QGKSLVP 433

Query: 398 -FIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXX 456
            F  NNSN  +A        P ++  K              Y +RT RY+  ++      
Sbjct: 434 LFKNNNSNWRDALYYHYYEYPGIHMVKRH------------YGVRTNRYKLIKFYYDVEA 481

Query: 457 XXXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVLSIRL 500
                       E+YD   DP E KN++  S YK I   L  +L
Sbjct: 482 W-----------EMYDLQEDPNEMKNIYGDSNYKEIQLELHKKL 514



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 39/142 (27%), Positives = 57/142 (40%), Gaps = 13/142 (9%)

Query: 11  NGDRVLTSDVETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQA 65
           N   V    V    N LFI+ DD     L    +K +  P+I+ L   G  F  AF   +
Sbjct: 24  NSKSVSEVSVFKKPNFLFIITDDHAYQALSAYDNKLINTPHIDRLANEGMLFKKAFVTNS 83

Query: 66  LCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNF-TTIPQFFKEHGYDTYSVGKVFH 124
           +C+PSR   LTG+       +   +  RD  +       T P+  +++GY+T   GK   
Sbjct: 84  ICSPSRAVALTGK-------FSHLNSVRDNLDVFDTLQVTFPKLLQKNGYETAIYGKWHL 136

Query: 125 PGKSSNFTDDYPYSWSEYPYHP 146
             K   F          + YHP
Sbjct: 137 KSKPKGFDFWEVLPDQGHYYHP 158


>UniRef50_Q2UNM0 Cluster: Sulfatases; n=1; Aspergillus oryzae|Rep:
           Sulfatases - Aspergillus oryzae
          Length = 615

 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 86/364 (23%), Positives = 152/364 (41%), Gaps = 26/364 (7%)

Query: 15  VLTSDVETPKNILFILIDDLRHLSDKKVYLPNI-NFLGKTGATFNNAFAQQALCAPSRNS 73
           V   + + P N + IL DD     D   Y+P +   L   G  FN+ +A  ALC P+R S
Sbjct: 17  VAKEEADKP-NFIVILTDDQDQQLDSMKYMPKVKKLLTDEGVYFNHHYATVALCCPARAS 75

Query: 74  LLTGRRPDSLRLYDF---YSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSN 130
           L TG+   +  + +    Y  +            +P + ++ GY TY  GK+ +   ++N
Sbjct: 76  LWTGKAAHNTNVTNLRPPYGGYPKFVEEGWISKWLPVYMQKSGYKTYFTGKLMNNHNANN 135

Query: 131 FTD---DYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQ 187
           + +   +      ++   P T  Y +  +         + N   P S        L   +
Sbjct: 136 YMNGLKEMGLDGHDFMIEPGTYQYTNTTI---------QHNFEKPRSYPGVYATDLLANK 186

Query: 188 SLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPL 247
           S+ +  D  K++   KPFFLAI    PH   ++ K + K +P +K H    P+  K    
Sbjct: 187 SMAWMDDAAKEK---KPFFLAINPVNPHNNYQWGKGWTKPVP-AKRHEGTFPD-AKVPRS 241

Query: 248 VSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIR-QSYYAAALYIDELIGILLSYVDM 306
           VS++P         +  L       +       + R Q+  A    ++  I  L  +  +
Sbjct: 242 VSFNP-DRPSGAAWVHELPQLSDAVIKDNDLYYRRRLQALQAVDDLVETTIDTLKRHKML 300

Query: 307 QKTIIVLTSDHGWSLGENGLW-AKYSNFDYALKVPLIFKSPKLIPTVVHEPV-ELIDIFP 364
             T I+ TSD+G+ + ++ L   K   ++  + VP+I + P +      + V   +DI P
Sbjct: 301 DNTYIIYTSDNGFHISQHRLMPGKRCPYEEDVNVPMIIRGPGIPKGKTADIVTSHLDIAP 360

Query: 365 TLVD 368
           T+V+
Sbjct: 361 TIVE 364


>UniRef50_A3HWG3 Cluster: Choline sulfatase; n=1; Algoriphagus sp.
           PR1|Rep: Choline sulfatase - Algoriphagus sp. PR1
          Length = 505

 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 95/367 (25%), Positives = 154/367 (41%), Gaps = 55/367 (14%)

Query: 25  NILFILIDDLRHLS-----DKKVYLPNINFLGKTGATFNNAFAQQ----ALCAPSRNSLL 75
           N+LF+  DD R  +     +  +  P I+ LG+ G+ F+NA+       A+C  SR  L 
Sbjct: 44  NVLFLFADDQRADALGINGNPYIQTPTIDQLGREGSRFSNAYVMGGVHGAICMSSRAMLF 103

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY 135
           +G+      LY       D+ +G+   T     F   GY T+  GK +H  K +    + 
Sbjct: 104 SGKN-----LYKV----TDKLSGEHTMT---MSFAAAGYRTFGTGK-WHNEKEAF---EA 147

Query: 136 PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDF 195
            +  ++  Y      + D  +       KL            + G S    Q    AIDF
Sbjct: 148 SFQEAKNVYLGGMADHYDLPLRDYGADGKLGE--------PTRKGFSTE--QFAQAAIDF 197

Query: 196 LK---KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHP 252
           +K   +RN  +PFF  + F  PH P      Y+   P        +  +P     + +HP
Sbjct: 198 IKDHGQRNTDQPFFCYVAFTAPHDPYSPEANYINHYP--------DGTLPLPGNYMPYHP 249

Query: 253 WTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV----DMQK 308
           +        +R  N+T  +   P    + I   YYA   ++D  I  +L+ +        
Sbjct: 250 FEFDHLT--VRDENLT-GWPRKPEVIQM-ILSDYYALVTHLDTQIAKILNTLKETGQYDN 305

Query: 309 TIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELI-DIFPTLV 367
           TIIV  +D+G + G +GL  K S ++++ KVPLI K P +      +    I D++PTL 
Sbjct: 306 TIIVYAADNGLAAGSHGLLGKQSLYEHSSKVPLIIKGPGVPQDQELDAFAYIHDLYPTLA 365

Query: 368 DLTKLSD 374
           +L  + D
Sbjct: 366 ELAGIPD 372


>UniRef50_Q7UYS7 Cluster: Mucin-desulfating sulfatase; n=1;
           Pirellula sp.|Rep: Mucin-desulfating sulfatase -
           Rhodopirellula baltica
          Length = 557

 Score = 69.3 bits (162), Expect = 2e-10
 Identities = 52/205 (25%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWH 251
           A++FL KR   +PF L + F   H     P+++L Q     +++  E  +P +    S+H
Sbjct: 261 ALEFLGKRPKDQPFCLTVAFFATHAEDGNPQQFLPQPESMHLYQDVEIPVPANATDESFH 320

Query: 252 PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQ---- 307
              +    D     N        P K+ + ++ +YY  A  +D   G +L  ++ Q    
Sbjct: 321 RLPEFVANDGNEGRNRYHWRFDTPEKYQIMMK-NYYRLATEVDSTCGRILKELEKQGVLD 379

Query: 308 KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT---VVHEPVEL-IDIF 363
            T+++ T+D+G+   E+GL  K+     +++VPLI + P++        +E   L +D+ 
Sbjct: 380 NTLVIFTTDNGYYHAEHGLADKWYPHQESIRVPLIIRDPRMSADKHGSTNEDFTLSVDLA 439

Query: 364 PTLVDLTKLSDEIPKCLNHKDTSQL 388
           PT+  L  +  E+P+ +  +D S L
Sbjct: 440 PTI--LNAVGAEVPESMQGRDMSVL 462



 Score = 34.3 bits (75), Expect = 7.7
 Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 12/124 (9%)

Query: 21  ETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLL 75
           + P N++ +  DD RH       +  V  P ++ L   G  F       ++C  SR  L 
Sbjct: 121 DAPMNVVVLYADDWRHDTLGVAGNPVVKTPTLDALASEGMRFTENCVTTSICGVSRACLF 180

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY 135
           TG+   S     F  +    +  Q    T P   +++GY    VGK +H GK      D+
Sbjct: 181 TGQWMSSHGCDGFKPF---ETPWQ---QTYPGILRDNGYYVGHVGK-WHNGKFPGEKFDF 233

Query: 136 PYSW 139
             S+
Sbjct: 234 GRSY 237


>UniRef50_A6C8U0 Cluster: Choline sulfatase; n=1; Planctomyces maris
           DSM 8797|Rep: Choline sulfatase - Planctomyces maris DSM
           8797
          Length = 479

 Score = 69.3 bits (162), Expect = 2e-10
 Identities = 55/199 (27%), Positives = 99/199 (49%), Gaps = 20/199 (10%)

Query: 190 DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVS 249
           D AI+F+++++  KPFFL + F  PH PL  P  Y +       + P +  +P +   + 
Sbjct: 201 DAAIEFVERKH-QKPFFLHVCFTAPHDPLLMPIGYEQN------YDPDQMPVPANF--LP 251

Query: 250 WHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV----D 305
            HP+ D    D      + +P      K  L +   YY+   ++D  +G ++  +    +
Sbjct: 252 QHPF-DHGNFDGRDEALLPWPRTKEIVKNDLSL---YYSVISHLDAQVGRIVKALKKTGE 307

Query: 306 MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKL-IPTVVHEPVELIDIFP 364
            + TI++ +SDHG ++G +GL  K + +++ + VPLI   P +   T+ +    L D++P
Sbjct: 308 WENTILIFSSDHGLAMGSHGLRGKQNMYEHTVNVPLIMVGPGIPADTLSNAQCYLRDLYP 367

Query: 365 TLVDLTKLSDEIPKCLNHK 383
           T  DL  +   IPK +  K
Sbjct: 368 TSCDLAGV--PIPKTVEGK 384



 Score = 41.9 bits (94), Expect = 0.039
 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 13/112 (11%)

Query: 22  TPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           T  NI+F+L DD R      L +  +  P+++ L K G +F  A     +C PSR  +L+
Sbjct: 32  TQPNIVFLLSDDQRPDTIAALGNPIIKTPHLDQLVKAGTSFTRAVCANPICTPSRAEILS 91

Query: 77  GRRPDSLRLYDFYSYWRDRSNG-QGNFTTIPQFFKEHGYDTYSVGKVFHPGK 127
           G       +  F++   D     +    T  Q   + GY+T+ VGK  + GK
Sbjct: 92  G-------VSGFHNGSMDFGKPIKKELPTWSQTLSKAGYNTWYVGKWHNDGK 136


>UniRef50_A4ASQ2 Cluster: Mucin-desulfating sulfatase; n=1;
           Flavobacteriales bacterium HTCC2170|Rep:
           Mucin-desulfating sulfatase - Flavobacteriales bacterium
           HTCC2170
          Length = 473

 Score = 69.3 bits (162), Expect = 2e-10
 Identities = 98/417 (23%), Positives = 173/417 (41%), Gaps = 62/417 (14%)

Query: 4   VVNIILLNGDRVLTSDVETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFN 58
           ++  ++L+    +  +VE   NILF L+DD R+          +  P ++ L + G  F 
Sbjct: 12  IIISLVLSACNTVQEEVEERPNILFFLVDDQRNDLLSIAGHPIIQTPTVDKLAENGVRFT 71

Query: 59  NAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYS 118
           NAF   ++CA SR S+LTG           Y++ +     +    + P   K  GY T  
Sbjct: 72  NAFVTTSICAASRASILTGLYESK----HGYTFGKLPIKTEFVKNSYPFLLKSSGYKTGF 127

Query: 119 VGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQ 178
           +GK     K  N     P     + Y+ P+       +  N  TK+    +         
Sbjct: 128 IGK--FGMKIENQDSLLP---QMFDYYKPSPKSGPHFIKLNDGTKRHSAEI--------- 173

Query: 179 PGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHI--PLKFP---KEYLKQMPISKV 233
                      D A++F+  +    PF L+I F+  H     K P     Y     +  +
Sbjct: 174 ---------KGDEAVEFIANQTSENPFCLSISFNAVHAVDGNKTPGNDGHYPYPKAVEHL 224

Query: 234 HRPKEPNIPK--DMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAAL 291
           +   E   P+  D  +   HP      ++ + R    + +     K+   ++  +   + 
Sbjct: 225 YEDTEMPTPELSDSNIYENHP---EFLKNSLNRERYFWRWDT-EEKYQTNMKAYFRMISG 280

Query: 292 Y---IDELIGILLSYVDMQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP-K 347
           Y   +  ++  L  Y   + TII+ +SD+G+ +G  G   K+S+++ +L+VPL+   P K
Sbjct: 281 YDNVMKRVLNTLEKYGLDKNTIIIFSSDNGYYMGNRGFAGKWSHYEESLRVPLVIYDPRK 340

Query: 348 LIPTV--VHEPVEL-IDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIEN 401
              TV    + V L IDI  T++DL  +S  +P+           ++G+SLVP + N
Sbjct: 341 SRKTVKGTSDKVALNIDIPSTILDLAGIS--LPE----------IYQGESLVPILNN 385


>UniRef50_Q3KJU8 Cluster: Sulfatase; n=6; Proteobacteria|Rep:
           Sulfatase - Pseudomonas fluorescens (strain PfO-1)
          Length = 536

 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 66/246 (26%), Positives = 108/246 (43%), Gaps = 34/246 (13%)

Query: 177 RQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRP 236
           R P Q    + + + AIDF+ ++ G KP+FL + + KPH P   P  Y        +  P
Sbjct: 203 RIPEQHSETVYTTNRAIDFIGEQ-GEKPWFLHLSYIKPHWPYIVPAPYHTLYSTKSILEP 261

Query: 237 KEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDEL 296
                P D P+     +   RK ++   LN    F   P +  L +  +Y      +D+ 
Sbjct: 262 VRNASPSDHPV-----YQAFRKHEE--SLN----FSKDPVR--LNVIPTYMGLVKQVDDQ 308

Query: 297 IGILLSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTV 352
           +G L  ++      + T+IV TSDHG  LG++ L  K    + A+ VPLI + P+    V
Sbjct: 309 LGRLFDFLQSNGRWEDTLIVFTSDHGDFLGDHWLGEKEFLLEQAVGVPLIVRDPRAAADV 368

Query: 353 VHEPV-----ELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLE 407
               V     E ID  PT ++   ++        H+       EG+SL+P +   +    
Sbjct: 369 TRGTVDERLAETIDGVPTFLEALGVTG-----AEHR------LEGRSLIPLLHGENPDWR 417

Query: 408 AFAISQ 413
            ++IS+
Sbjct: 418 RYSISE 423



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 36/110 (32%), Positives = 53/110 (48%), Gaps = 12/110 (10%)

Query: 18  SDVETP-KNILFILIDDLR--HLS---DKKVYLPNINFLGKTGATFNNAFAQQALCAPSR 71
           S+ + P +N+L+I+ D LR  +LS      ++ PNI+ L   G  F+ A+ Q  +C PSR
Sbjct: 2   SNPQNPVRNVLYIMCDQLRRDYLSCYGHPHLHTPNIDRLAAAGVRFSRAYTQGTICGPSR 61

Query: 72  NSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK 121
            S  TGR   S ++      W           TI  + + HG  T  VGK
Sbjct: 62  MSAYTGRYVSSHQV-----AWNAVPLPLEEL-TIGDYLRPHGIRTALVGK 105


>UniRef50_Q2JAY4 Cluster: Sulfatase precursor; n=1; Frankia sp.
           CcI3|Rep: Sulfatase precursor - Frankia sp. (strain
           CcI3)
          Length = 524

 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 90/362 (24%), Positives = 146/362 (40%), Gaps = 49/362 (13%)

Query: 25  NILFILIDDLRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLR 84
           NI+FIL DDL          P+I  L + G TF++ F   +LC PSR+S+ TG  P   +
Sbjct: 57  NIVFILTDDLSWNLVTDQIAPHITALERQGETFDHYFVTDSLCCPSRSSIFTGLLPHDTK 116

Query: 85  LYDFYS----YWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNF---TDDYPY 137
           +    S    Y + +  G     T     +  GY T  +GK  +          T   P 
Sbjct: 117 VETNLSPDGGYGKFQQEGLAG-RTFAVALQAAGYQTSMLGKYLNGYGDPTITPTTGPVPR 175

Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
            WS++ +   T  Y +    +N               V+   GQ    +  L+       
Sbjct: 176 GWSDW-HVSNTTGYAELNFDQNDNG-----------VVRHYAGQDNYGVDVLNADAQAFI 223

Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVR 257
           +R+  KPF L +  + PH P           P   +  P++P+              +  
Sbjct: 224 RRSAGKPFALEVATYAPHQPYTPAPRNADDFP--GLTEPRDPSF-------------NTN 268

Query: 258 KRDDIRRLNITFPFGVMPTKWTLKIRQSY---YAAALYIDELIG----ILLSYVDMQKTI 310
             D    L    P  + P+  T  + Q+Y     A   +D+L+G     L +   +  T 
Sbjct: 269 NTDAPAWLGQRAP--LAPSVLT-NLDQAYRERAQAVESVDKLVGDTEATLAAEHLLDNTY 325

Query: 311 IVLTSDHGWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIP--TVVHEPVELIDIFPTLV 367
            V +SD+G+ LG++ L   K + FD  ++VPLI   P  +P   V+ +  + +D++PT  
Sbjct: 326 FVFSSDNGYHLGQHRLVRGKQTAFDTDIRVPLIVTGPG-VPHGRVISQVAQNVDLYPTFT 384

Query: 368 DL 369
           DL
Sbjct: 385 DL 386


>UniRef50_Q9VEX0 Cluster: Extracellular sulfatase SULF-1 homolog
           precursor; n=3; Diptera|Rep: Extracellular sulfatase
           SULF-1 homolog precursor - Drosophila melanogaster
           (Fruit fly)
          Length = 1114

 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 90/357 (25%), Positives = 149/357 (41%), Gaps = 33/357 (9%)

Query: 21  ETPKNILFILIDDLRHLSDKKVYLPN-INFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           E   NI+ IL DD         ++P  +  L   GA F +A+    +C P+R+SLLTG  
Sbjct: 51  ERRPNIILILTDDQDVELGSLNFMPRTLRLLRDGGAEFRHAYTTTPMCCPARSSLLTGMY 110

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFT-TIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
             +  ++              + T +   +    GY T   GK  +    S      P  
Sbjct: 111 VHNHMVFTNNDNCSSPQWQATHETRSYATYLSNAGYRTGYFGKYLNKYNGSYI----PPG 166

Query: 139 WSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFL-- 196
           W E+        Y +  +  N   +K++                 PDL + D +I FL  
Sbjct: 167 WREWGGLIMNSKYYNYSI--NLNGQKIKHGF-------DYAKDYYPDLIAND-SIAFLRS 216

Query: 197 -KKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQM-PISKVHRPKEPNIPKDMPLVSWHPWT 254
            K++N  KP  L + F  PH P     +Y      ++  H P   + P   P   W    
Sbjct: 217 SKQQNQRKPVLLTMSFPAPHGPEDSAPQYSHLFFNVTTHHTPSYDHAPN--PDKQWI--- 271

Query: 255 DVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLT 314
            +R  + ++ ++  F   ++ TK  L+  QS   A   ++ +   L    ++  T IV T
Sbjct: 272 -LRVTEPMQPVHKRFT-NLLMTK-RLQTLQSVDVA---VERVYNELKELGELDNTYIVYT 325

Query: 315 SDHGWSLGENGL-WAKYSNFDYALKVPLIFKSPKL-IPTVVHEPVELIDIFPTLVDL 369
           SDHG+ LG+ GL   K   F++ ++VP + + P +    VV+E V  +D+ PT +D+
Sbjct: 326 SDHGYHLGQFGLIKGKSFPFEFDVRVPFLIRGPGIQASKVVNEIVLNVDLAPTFLDM 382


>UniRef50_Q3M597 Cluster: Twin-arginine translocation pathway signal
           precursor; n=1; Anabaena variabilis ATCC 29413|Rep:
           Twin-arginine translocation pathway signal precursor -
           Anabaena variabilis (strain ATCC 29413 / PCC 7937)
          Length = 457

 Score = 68.5 bits (160), Expect = 4e-10
 Identities = 65/212 (30%), Positives = 102/212 (48%), Gaps = 25/212 (11%)

Query: 25  NILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNSLLTG- 77
           N++FIL+DD+    D  +Y       PN++ L + G  F NA+A Q +C P+R + LTG 
Sbjct: 43  NVVFILVDDMGW-GDLSIYGRTDYETPNLDRLARQGVRFTNAYANQTVCTPTRIAFLTGR 101

Query: 78  ---RRPDSLRLYDFYSYWRDRSNGQG---NFTTIPQFFKEHGYDTYSVGKVFHPGKSSNF 131
              R P  LR     +  +  SN  G   N  TI    K +GY+T  VGK +H G   NF
Sbjct: 102 YQARLPVGLR-EPLGARSQPASNNIGIPANQPTIASLLKANGYETALVGK-WHAGYPPNF 159

Query: 132 TDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDY 191
                  + EY  H    +        ++     E ++  PV    Q    + DL + D 
Sbjct: 160 -GPLQKGFDEYFGHLSGGIEYFTHTGTDRILDLYENDV--PV----QRSGYVTDLFT-DR 211

Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKE 223
           A++F+ +R  S+PF+L++ ++ PH P + P +
Sbjct: 212 AVEFI-QRPHSRPFYLSLHYNAPHWPWQGPND 242


>UniRef50_A6DKP2 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;
           Lentisphaera araneosa HTCC2155|Rep:
           N-acetylgalactosamine 6-sulfatase - Lentisphaera
           araneosa HTCC2155
          Length = 446

 Score = 68.5 bits (160), Expect = 4e-10
 Identities = 55/212 (25%), Positives = 92/212 (43%), Gaps = 11/212 (5%)

Query: 25  NILFILIDDL-----RHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NI+ +  DD+      +   +    P I+ + K G  F   +A  ++C PSR  +LTGR 
Sbjct: 21  NIVLVFADDMGWGDVAYHGVEDAQTPAIDAIAKGGVWFEQGYAAASVCGPSRAGILTGRY 80

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
                +       +     Q N   I +  K  GY + + GK     K   F +D  +  
Sbjct: 81  QQLFGVVTNGDADKGIPKSQKN---IAELLKPAGYKSGAFGKWHLGSKKGQFPNDRGFD- 136

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKR 199
           + Y +H     Y  A    NKK K           V  + G  L + +  D+A++F+++ 
Sbjct: 137 TFYGFHFGAHDYYRADKKLNKKKKGYAPIYFNQDIVDYKEGDYLTE-KITDHAVEFIEE- 194

Query: 200 NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPIS 231
           N  +PFF+ + ++  H P + P EYL ++P S
Sbjct: 195 NKDQPFFMYVAYNSVHSPWQVPDEYLARIPES 226


>UniRef50_Q8A3A3 Cluster: Mucin-desulfating sulfatase; n=4;
           Bacteroidetes|Rep: Mucin-desulfating sulfatase -
           Bacteroides thetaiotaomicron
          Length = 518

 Score = 68.1 bits (159), Expect = 5e-10
 Identities = 99/393 (25%), Positives = 155/393 (39%), Gaps = 73/393 (18%)

Query: 25  NILFILIDDLRHLSD----------KKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSL 74
           NILFIL DD  H S           +  +  NI  L K G   +N F   ++ APSR S+
Sbjct: 29  NILFILSDD--HTSQAWGIYGGVLAEYAHNANIRRLAKEGVVLDNCFCTNSISAPSRASI 86

Query: 75  LTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDD 134
           LTG      RLY          +   +  T+    + +GY T  VGK     +   F D 
Sbjct: 87  LTGLYSHRNRLYTL------ADSLDTSIPTLATLLQANGYHTGLVGKWHIQSQPQGF-DY 139

Query: 135 YPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAID 194
           Y   + +  Y  PT +        N +    ER L          G S  DL + + AI 
Sbjct: 140 YSIFYDQGEYRDPTFIESTDPWPGNHQFG--ERVL----------GFST-DLVT-EKAIR 185

Query: 195 FLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWT 254
           ++K+++G++PF +   F   H P  +P        I   H       P+   L+ W P T
Sbjct: 186 WMKEQDGNQPFLMCCHFKATHEPYDYP--------IRMEHLYDGVTFPEPENLLDWGPET 237

Query: 255 DVR--KRDDIRRLNITFPFGVM-PTKWTL-----------------------KIRQSYYA 288
           + R  K   +  L   +      P KW                         K  + Y  
Sbjct: 238 NGRSFKGQTLEELERRWRIASQDPDKWWCRYPGLPFSTEGMQRTAARRASYQKFIRDYLR 297

Query: 289 AALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFK 344
               +D+ IG LL+ +D       TI++  SD G+ LGE+G + K   ++ + ++P + +
Sbjct: 298 CGATVDDNIGKLLNALDEMNIADNTIVIYVSDQGYFLGEHGFFDKRMFYEESARMPFVIR 357

Query: 345 SPKLIPT--VVHEPVELIDIFPTLVDLTKLSDE 375
            PK +P    + + +  +D  PTL +   +  E
Sbjct: 358 YPKKVPAGKRLDDLILNVDFAPTLAEFAGVKME 390


>UniRef50_A6DFB5 Cluster: Mucin-desulfating sulfatase; n=2;
           Lentisphaera araneosa HTCC2155|Rep: Mucin-desulfating
           sulfatase - Lentisphaera araneosa HTCC2155
          Length = 462

 Score = 68.1 bits (159), Expect = 5e-10
 Identities = 94/350 (26%), Positives = 154/350 (44%), Gaps = 54/350 (15%)

Query: 7   IILLNGDRVLTSDVETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAF 61
           ++LL+   +  S  E P NI+F L+DD R+          +  PNI+ L   G  F NAF
Sbjct: 16  LLLLSLTTLAISAAEKP-NIVFFLVDDQRNDFLGCTGHPIIQTPNIDKLADQGTLFKNAF 74

Query: 62  AQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK 121
              A C  SR S+LTG     +R + F        N +   T+ P   K+ GY T   GK
Sbjct: 75  VTTATCWVSRASILTGM---YMRKHRFQG---GLINPKYIATSYPMGLKKAGYQTAYFGK 128

Query: 122 VFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAK-VCRNKKTKKLERNLICPVSVKRQPG 180
                  ++F  D              +M+ + K V RN   KK+        S+K +  
Sbjct: 129 -------THFRLDKKQQ---------AKMFDEFKQVGRNPFHKKMPDG-----SLKHE-- 165

Query: 181 QSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPN 240
               D+ + D AIDF+K+++  KPFF+ + F+  H      K++    P S  H   +  
Sbjct: 166 ---TDIIA-DLAIDFIKRQSEEKPFFVNMNFNATHAEDSDKKDHF-PYPESAAHLYTD-- 218

Query: 241 IPKDMPLVSWHPWTDVRKRDDIRR---LNITFPF-GVMPTKWTLKIRQSYYAAALYIDEL 296
               MPL   H       +    +    N  + +    P K+   +R +Y   A  ID  
Sbjct: 219 --MTMPLPKLHDRKIFESQPKFMQNSMHNDRYKWRWDTPEKYQHNMR-NYLRMASGIDFA 275

Query: 297 IGILLSYVDMQ----KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLI 342
           +G ++  +  +     T+I+ T+D+G+  G+ G   K+++++ +L+VPLI
Sbjct: 276 LGRVVDALKEKNLNDNTVIIYTADNGYYAGDRGFAGKWTHYEQSLRVPLI 325


>UniRef50_A6CAR8 Cluster: N-acetylgalactosamine 6-sulfate sulfatase;
           n=1; Planctomyces maris DSM 8797|Rep:
           N-acetylgalactosamine 6-sulfate sulfatase - Planctomyces
           maris DSM 8797
          Length = 501

 Score = 68.1 bits (159), Expect = 5e-10
 Identities = 94/381 (24%), Positives = 151/381 (39%), Gaps = 54/381 (14%)

Query: 21  ETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLL 75
           ETP NI+ I+ DD     L     +++  P+++ L K GA   + +     C PSR SLL
Sbjct: 35  ETPPNIIMIVSDDQGYRDLGSFGSEEIMTPHLDRLAKEGAKLTSFYVTWPACTPSRGSLL 94

Query: 76  TGRRPDSLRLYDF----------------YSYWRDRSNGQG-NFTTIPQFFKEHGYDTYS 118
           TGR P    +YD                 Y    +R  G       +P   K  GY +  
Sbjct: 95  TGRYPQRNGIYDMIRNEAPDFGHKYKPAEYEVTFERIGGMDVREKLLPALLKPAGYVSAI 154

Query: 119 VG-------KVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLIC 171
            G       K F P  +  F D Y ++ +   Y    E Y    + RN +  + ++   C
Sbjct: 155 YGKWDLGIHKRFLP-LARGFDDFYGFTNTGIDYF-THERYGVPSMYRNNQPTEEDKGTYC 212

Query: 172 PVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPIS 231
               +R+             A+ F+K+ N  KPFFL + F+ PH                
Sbjct: 213 TYLFQRE-------------AVRFIKE-NHQKPFFLYLPFNAPHGASSLDPRIRGGAQAP 258

Query: 232 KVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAAL 291
           + ++   P++   +         + R+R D          GV  +K  L+   S      
Sbjct: 259 EKYKNMYPHLKDTLVTKKKTGRYEFRERPD----GPVIHQGVSASKRRLEYVASITCMDD 314

Query: 292 YIDELIGILLSYVDMQKTIIVLTSDHGWSLGENGLWAKYSN---FDYALKVPLIFKSP-K 347
            I E++G+L  Y     TI+V  SD+G S G +    K      F+  ++VP + + P K
Sbjct: 315 AIGEVLGLLDEYQIADNTIVVFFSDNGGSGGADNSPLKGKKGMMFEGGIRVPCLVRYPAK 374

Query: 348 LIP-TVVHEPVELIDIFPTLV 367
           + P TV  E +  +++ PT +
Sbjct: 375 IKPGTVNDELLTSLELVPTFL 395


>UniRef50_Q7UVD9 Cluster: N-acetylgalactosamine 6-sulfate sulfatase;
           n=1; Pirellula sp.|Rep: N-acetylgalactosamine 6-sulfate
           sulfatase - Rhodopirellula baltica
          Length = 564

 Score = 67.7 bits (158), Expect = 7e-10
 Identities = 79/298 (26%), Positives = 128/298 (42%), Gaps = 58/298 (19%)

Query: 45  PNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYS------YWRDRSN- 97
           PN++ L   GA F N F    +C+P+R +L+TGR    L + DF        Y  D    
Sbjct: 135 PNMDRLAAEGAVFRNFFCTTPVCSPARATLMTGRYASELGIKDFIPQPGHKLYDPDSPIH 194

Query: 98  -GQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKV 156
               N  T  +  ++ GY T  VGK +H G       D+  +  +   HP    +     
Sbjct: 195 LDPDNTVTFAEVMQQQGYTTGLVGK-WHLG-------DWTAN-GDSGKHPTRHGFDSFMG 245

Query: 157 CRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHI 216
                T      L   ++ K Q  Q L      D+AIDF+++ N  +PFFL +    PH 
Sbjct: 246 LTGGGTTPDNPEL--ELNGKVQQFQGLTTDILTDHAIDFVEQ-NADRPFFLCLSTRAPHG 302

Query: 217 PLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFP-FGVMP 275
                    + +P++          P+D     W P+ +         ++ T P +  + 
Sbjct: 303 ---------RWLPVA----------PED-----WQPYEE---------MDPTIPQYPDLD 329

Query: 276 TKWTLKIRQSYYAAALYIDELIGILLSYVDMQK----TIIVLTSDHGWSLGENGLWAK 329
           T W  K  + Y A+   +D  +G LL  +D Q+    TI++ TSDHG+++G +G++ K
Sbjct: 330 TDWVRKKMKEYLASTSGVDRNLGRLLKTLDAQELTSNTIVIFTSDHGFNMGHHGIYHK 387


>UniRef50_Q15XI1 Cluster: Sulfatase; n=2; Bacteria|Rep: Sulfatase -
           Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 510

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 105/420 (25%), Positives = 174/420 (41%), Gaps = 87/420 (20%)

Query: 3   YVVNIILLNGDRVLTS---DVETPKNILFILIDDLRHLSDKKVY-------LPNINFLGK 52
           Y++ I L+  + VL S    V T  N+L IL+DDL + SD K Y        PNI+ L  
Sbjct: 15  YLLFITLIVCESVLNSCAAQVVTKPNVLLILVDDLGY-SDIKAYNENSFYDTPNIDKLAS 73

Query: 53  TGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNF---------- 102
               F N +A   +C+PSR +LLTG+ P   +  D++    D+    G F          
Sbjct: 74  QSVMFTNGYAANPVCSPSRFALLTGKHPTRGKATDWFPA-NDKPARAGRFLPAEFNDALP 132

Query: 103 ---TTIPQFFKEHGYDTYSVGKVFHPGKSSN-------FTDDYPYSWSEYPYHPPTEMYK 152
               T+ + FK++GY+T  +GK +H GK+ +       F  +   + + +P       YK
Sbjct: 133 LSEITLAEAFKQNGYNTAFLGK-WHLGKTEDLWPENQGFDVNIAGTKNGHPAAGYFSPYK 191

Query: 153 DAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFH 212
           +A++    K + L + L            SL D           K    + PFF+ + F+
Sbjct: 192 NARLTDGPKGEYLTQRL-------TNEAISLVD-----------KYSKQTVPFFMMLSFY 233

Query: 213 KPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFG 272
             H PL  P + +++               ++  +     W    KR+   R+    P  
Sbjct: 234 TVHTPLAAPNKDVQEYQAKIRQYAHNDEFQREEQV-----WPTAEKRE--VRVKQNHP-- 284

Query: 273 VMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM----QKTIIVLTSDHGWSLGENG--- 325
                       +Y A    +D  +G LL+ +      + T++V TSD+G      G   
Sbjct: 285 ------------TYAAMVKQMDTQVGRLLAKLKQAGMEESTLVVFTSDNGGLSSAEGSPT 332

Query: 326 -----LWAKYSNFDYALKVPLIFKSP--KLIPTVVHEPVELIDIFPTLVDLTKLSDEIPK 378
                   K   ++  ++VPL+ K P  K     ++EPV   D++PTL+    L D +P+
Sbjct: 333 SNLPLRGGKGWLYEGGIRVPLLVKLPQKKHKHLQINEPVTSTDLYPTLLSAGHL-DLLPQ 391


>UniRef50_A6CCV5 Cluster: Sulfatase; n=3; Bacteria|Rep: Sulfatase -
           Planctomyces maris DSM 8797
          Length = 406

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 58/189 (30%), Positives = 90/189 (47%), Gaps = 23/189 (12%)

Query: 190 DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPK-EPNIPKDMPLV 248
           D AI+F+++ +  +P+ L I  + PH P   P++Y K    + +  P  E +      L+
Sbjct: 113 DRAIEFIEQDH-QQPWLLNINVYDPHPPFTPPEKYAKMFDPAAMPGPHFEESDKATQELL 171

Query: 249 SWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM-- 306
           S   +  V    +I  L               K++  YYA    ID+    +LS +D   
Sbjct: 172 SRVDFQPVTMSTEISELK--------------KVQALYYAMIAQIDDQFARILSVLDSTG 217

Query: 307 --QKTIIVLTSDHGWSLGENGLWAKYSNF-DYALKVPLIFKSPKLIPTVVHEP--VELID 361
               T+I+ TSDHG +LG++GL  K   F +  ++VPLIF  P    T       VEL+D
Sbjct: 218 QRDNTVIIFTSDHGETLGDHGLVQKGCRFYEGLIRVPLIFSWPGHFVTNQRATGLVELLD 277

Query: 362 IFPTLVDLT 370
           +  TL+DLT
Sbjct: 278 LSATLLDLT 286


>UniRef50_A0JAV3 Cluster: Sulfatase precursor; n=1; Shewanella
           woodyi ATCC 51908|Rep: Sulfatase precursor - Shewanella
           woodyi ATCC 51908
          Length = 356

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 64/222 (28%), Positives = 103/222 (46%), Gaps = 34/222 (15%)

Query: 25  NILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           N++ I +DDL  + D  +Y       PNI+ L  +G  F  A+A  A CAPSR SL+TG 
Sbjct: 39  NVVIIYVDDLG-IMDTGIYGSAQYPTPNIDKLANSGVRFTQAYANAANCAPSRASLMTGL 97

Query: 79  RPDSLRLYDFYSYWRDRS----------NGQGN--FTTIPQFFKEHGYDTYSVGKVFHPG 126
            P    +    S  R  S          N + N   TTI   FK+ GY T  +GK +H G
Sbjct: 98  TPAEHGILTVGSSERGESQYRKLIPVTNNTELNPDLTTIADLFKQQGYATAVIGK-WHLG 156

Query: 127 KSSNFTDDYPYS-WSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPD 185
           K++     +  +  + +  HPP+  Y  +K    +K   LE   +    +  +  +    
Sbjct: 157 KTAPTEYGFDTAIAASHLGHPPSYFYPYSK--GKRKLIGLEEGGLKDEYLSNRITRE--- 211

Query: 186 LQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQ 227
                 A++++  +   +PFFL + F+  H P++ PKE++ Q
Sbjct: 212 ------AVNYISSQR--QPFFLYLPFYAVHTPIEAPKEWVNQ 245


>UniRef50_A5P719 Cluster: Iduronate sulfatase; n=1; Erythrobacter
           sp. SD-21|Rep: Iduronate sulfatase - Erythrobacter sp.
           SD-21
          Length = 216

 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 57/216 (26%), Positives = 100/216 (46%), Gaps = 31/216 (14%)

Query: 25  NILFILIDDLRHLS------DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           ++L + IDDL   +         V+ PNI+ L   G TF N F+Q ALC PSR S +TG 
Sbjct: 2   SVLVVSIDDLAAFAFFQQYYGGTVHTPNIDRLMAMGTTFENGFSQVALCNPSRTSAMTGL 61

Query: 79  RPDSLRLY-DFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPY 137
            P    ++ +   YW   +  Q +   + QF    GY T  +GKV H   +    DDY  
Sbjct: 62  SPAHTGVHNNAVEYW---NAVQADDLLMSQFMNA-GYHTSMIGKVMH---TPRVPDDYGS 114

Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
            +++Y       ++++ +    ++   +E +       + + G    D  ++  AI+ L+
Sbjct: 115 RFADY-------IFEEREDVGGREIGVMEPD------DRSENG----DEVNVAQAIELLQ 157

Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKV 233
             +   PF + +G +KPH+    P+E+    P+  +
Sbjct: 158 SYSSDDPFAMFVGINKPHLNWVVPQEFYDLYPLESI 193


>UniRef50_A4AAM5 Cluster: Sulfatase; n=1; Congregibacter litoralis
           KT71|Rep: Sulfatase - Congregibacter litoralis KT71
          Length = 500

 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 108/395 (27%), Positives = 158/395 (40%), Gaps = 69/395 (17%)

Query: 7   IILLNGDRVLTSDVETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNA 60
           +  L+G            N+L I +DDL    D  VY       P+I+ L   G  F   
Sbjct: 29  VAALSGASASAQAASDRHNVLVIYVDDLG-FGDTGVYGHRVVKTPHIDGLAAEGIRFTQF 87

Query: 61  FAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVG 120
           +A  ALC+PSR  LLTGR P    +  +      R +     TT+    K  GY T  +G
Sbjct: 88  YAPSALCSPSRAGLLTGRTPYRTGVESWIPD-DSRVHLGRRETTLADLAKARGYRTAVIG 146

Query: 121 KVFHPGKSSNFTD-DYPYSWS-EYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKR- 177
           K +H     +  D   P  +  +Y Y       K+A V     T+   R  + P ++ R 
Sbjct: 147 K-WHLNGGLHMRDVPQPRDFGFDYQY-GLAAWVKNASVA--DSTELPRRGPMFPDNMYRN 202

Query: 178 QPGQSLPDLQSL----DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKV 233
                + D  S     D AI +L+    S PFFL + + + H P+  P  YL        
Sbjct: 203 NEPVGVTDKYSAELVSDEAIGWLQA--SSDPFFLLLTYSEVHTPIASPPAYL------DA 254

Query: 234 HRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYI 293
           +R    +  K  P + +  W   R R                  W  + R  YYA   ++
Sbjct: 255 YREYLSDEAKHNPFLYYFDW---RNR-----------------PW--RGRGEYYANISFL 292

Query: 294 DELIGILLSYVDMQK----TIIVLTSDHG---------WSLG----ENGLWAKYS-NFDY 335
           D  +G ++ ++  QK    T+IV +SD+G         W LG      GL  K    F+ 
Sbjct: 293 DAQLGRVIGHLRDQKILDNTLIVFSSDNGPVTDAALTPWELGMAGETGGLRGKKRFLFEG 352

Query: 336 ALKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVD 368
            ++VP I + P  I    V H  V  +DIFPTL +
Sbjct: 353 GIRVPGIIRYPHRIEAGRVEHRAVTALDIFPTLAE 387


>UniRef50_A0Z632 Cluster: Arylsulfatase B; n=1; marine gamma
           proteobacterium HTCC2080|Rep: Arylsulfatase B - marine
           gamma proteobacterium HTCC2080
          Length = 545

 Score = 66.1 bits (154), Expect = 2e-09
 Identities = 92/370 (24%), Positives = 159/370 (42%), Gaps = 68/370 (18%)

Query: 25  NILFILIDDLRHLS----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           NIL ++ DDL           +  P+++ L + G   N  F    +C+P+R +L+TGR P
Sbjct: 34  NILIMVADDLGWADVGYHGGDIDTPSLDRLAQQGVRLNR-FYTTPICSPTRAALMTGRDP 92

Query: 81  DSLRL-YDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK--------VFHPGKSSNF 131
             L + Y     W D      +   +P+ F+  GY T  +GK         +HP  +  F
Sbjct: 93  IRLGVTYGVIFPW-DNIGVHPDEHFMPETFQAAGYQTAIIGKWHLGHAQMTYHPN-NRGF 150

Query: 132 TDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDY 191
              Y +  +E  ++PP           N+  K  +RN    VS+  Q  ++       D 
Sbjct: 151 EHFYGHLHTEVGFYPPFS---------NQGGKDFQRN---GVSIDDQGYETY---LLADE 195

Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWH 251
              ++++R+  +PF + + F  PH PL  P E           + K  +I  D+P+    
Sbjct: 196 VSRYIRERDRDRPFLVYMPFIAPHTPLDAPVEL----------QDKYKDIETDLPMAR-- 243

Query: 252 PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQ---- 307
                R+ DD R ++      + P+      R  Y A    +D+ IG +L  +D +    
Sbjct: 244 ----SRQTDDTRLISRVM---LQPS-----ARPMYAAVVDAMDQAIGRVLDTLDQEGISD 291

Query: 308 KTIIVLTSDHGWSL----GENGL---WAKYSNFDYALKVPLIFKSPKLI-PTVVHEPV-E 358
            TI++  SD+G +     G N       K   F+  ++V  + + P ++ P  + E +  
Sbjct: 292 NTIVLFFSDNGGAAYSYGGANNAPLRGGKGETFEGGIRVTSLMRWPAMLEPGQIFEQIMS 351

Query: 359 LIDIFPTLVD 368
           ++D+FPTLVD
Sbjct: 352 VMDVFPTLVD 361


>UniRef50_UPI0000E0EEBA Cluster: mucin-desulfating sulfatase
           (N-acetylglucosamine-6-sulfatase); n=3; alpha
           proteobacterium HTCC2255|Rep: mucin-desulfating
           sulfatase (N-acetylglucosamine-6-sulfatase) - alpha
           proteobacterium HTCC2255
          Length = 524

 Score = 65.7 bits (153), Expect = 3e-09
 Identities = 64/223 (28%), Positives = 105/223 (47%), Gaps = 17/223 (7%)

Query: 180 GQSLPDLQSL-DYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPK 237
           G+++P    + + A DF+++ +N  KP+ ++I F  PH   K   EY    P       +
Sbjct: 198 GKTIPQTYYMAELAKDFIEQNKNTDKPWTISISFRNPHAHDK-DHEYQYHYPAELESLYQ 256

Query: 238 EPNIP--KDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDE 295
           +  IP  K      +    D  K+  I R    + FG        K+ + +Y A   +D 
Sbjct: 257 DVTIPPTKFSSDEDFAALPDFLKKS-IARDRWHYRFGSEAIYQ--KMAKRHYRAITAVDR 313

Query: 296 LIGILLSY-----VDMQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP 350
            +G++        VD + TII+ T D+G+S+ E  L  K+  +D  L+VPLI   P+   
Sbjct: 314 AVGMIYDKLVETGVD-ENTIIIYTGDNGYSMNERQLAGKWFGWDEDLQVPLIIFDPRQPK 372

Query: 351 TVVHEPVEL-IDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEG 392
             V + V L IDI PT++D+  +  EIPK    K  +++   G
Sbjct: 373 AQVRDEVALNIDIAPTILDMAGV--EIPKRYQGKSLTKIVAGG 413



 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 39/121 (32%), Positives = 62/121 (51%), Gaps = 9/121 (7%)

Query: 21  ETPKNILFILIDDLRHLSDKKVY----LPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           E   NILF+L DD R     K++     PN++ L   G  F+NAF    +CA SR S +T
Sbjct: 69  EKKPNILFLLADDHRWDLIGKIHPIIKTPNLDQLADKGTFFSNAFVTTPICAASRVSFVT 128

Query: 77  GRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
           G    + R +D Y++ R   + +    T P+  KE GY++  +GK +    S + ++ + 
Sbjct: 129 GL---TERTHD-YTFLRPDVSPEDTAITYPKLLKESGYNSAFIGK-YGMALSGDLSEHFD 183

Query: 137 Y 137
           Y
Sbjct: 184 Y 184


>UniRef50_A6DRX0 Cluster: N-acetylgalactosamine 6-sulfate sulfatase;
           n=3; Bacteria|Rep: N-acetylgalactosamine 6-sulfate
           sulfatase - Lentisphaera araneosa HTCC2155
          Length = 486

 Score = 65.7 bits (153), Expect = 3e-09
 Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 20/210 (9%)

Query: 22  TPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           T  NILFI++DDL          + +  PNI+ L   G  FNNA++  + C PSR +LLT
Sbjct: 31  TQPNILFIMVDDLGKEWISCYGAEDIKTPNIDALAAGGMIFNNAYSMPS-CTPSRTTLLT 89

Query: 77  GRRPDSLRLYDFYSYWRDRSNGQGNF-------TTIPQFFKEHGYDTYSVGKVFHPGKSS 129
           G+ P       + ++W     G G F       TT  +  K+ GY T++ GK        
Sbjct: 90  GKYPFRT---GYVNHWDVPRWGIGYFDWKQKPNTTFARLMKDLGYRTFATGKWQLNDFRL 146

Query: 130 NFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKL-ERNLICPVSVKRQPGQSLPDLQS 188
                  + + ++      E  KD K    K T++    ++      K   GQ  PDL +
Sbjct: 147 EPLAMQKHGFDDWAMWTGCETSKD-KTHEKKSTQRYWNAHINTKEGSKTYKGQFGPDLYT 205

Query: 189 LDYAIDFLKKRNGSKPFFLAIGFHKPHIPL 218
            D+ I+F++K N  KP  +      PH P+
Sbjct: 206 -DHLINFMRK-NKDKPMCIYYPMVLPHTPV 233


>UniRef50_Q7UZ42 Cluster: Mucin-desulfating sulfatase; n=5;
           Bacteria|Rep: Mucin-desulfating sulfatase -
           Rhodopirellula baltica
          Length = 539

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 95/401 (23%), Positives = 172/401 (42%), Gaps = 58/401 (14%)

Query: 25  NILFILIDD-----LRHLSDKKVYL---PNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           NILFI+ DD     +     +  YL   PN++ L K G  F NAF   ++C PSR  ++T
Sbjct: 30  NILFIMSDDHTSQAVGAYGSRLAYLDPTPNLDRLAKEGMLFENAFCTNSICTPSRACIMT 89

Query: 77  GRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
           G+   +  ++D       ++        + +  K+ GY T  +GK     + + F  DY 
Sbjct: 90  GQYNHTNGVFDLNGRIEPKNQ------HLAKEMKKAGYQTAMIGKWHLKAEPAAF--DY- 140

Query: 137 YSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAID-F 195
                Y   P    Y D +  R +  K   +N I      ++ G    D  + D  ++ F
Sbjct: 141 -----YCVLPGQGKYFDPEF-RIQGDKPWPKNTI------KKEGMHSTDAIT-DITLNWF 187

Query: 196 LKKRNGSKPFFLAIGFHKPHIPLKFP---KEYLKQMPISKV----HRPKEPNIPKDMPLV 248
            + R   KPFFL   +  PH   ++    +EYL ++ I +      +P+  ++       
Sbjct: 188 DEVREDGKPFFLMHHYKAPHDFFEYAPRYEEYLAEIAIPEPKNLWSQPQFGSLATRGAND 247

Query: 249 SWHPW--TDVRKRDDIRRLNITFPFGV-------MPTKWTLKIRQSYYAAALY-IDELIG 298
              P+  T + +R+   R N    +GV          +    I   +Y   +  +D+ + 
Sbjct: 248 EMMPYIGTSIGRRNP--RRNYASHYGVDSWLSDEDAKREAYNIYMKHYLRCVKGVDDNLA 305

Query: 299 ILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TV 352
            L + ++    M  T+I+ T D G+ LGE+    K   +D + ++P + + PK +P  + 
Sbjct: 306 RLFAKLEETGQMDNTVIIYTGDQGFMLGEHDYMDKRWMYDESQRMPFLVRYPKSVPAGSR 365

Query: 353 VHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGK 393
            +  VE +D  PT++    +  E P+ +  K   ++C  G+
Sbjct: 366 SNAIVENVDYGPTMLAFAGV--ETPEYMQGKSFREICETGQ 404


>UniRef50_Q12Q17 Cluster: Sulfatase; n=1; Shewanella denitrificans
           OS217|Rep: Sulfatase - Shewanella denitrificans (strain
           OS217 / ATCC BAA-1090 / DSM 15013)
          Length = 458

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 48/215 (22%), Positives = 106/215 (49%), Gaps = 15/215 (6%)

Query: 190 DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVS 249
           D  I+++  + G +  F+ + + +PH P   P  Y +  P     +P E ++   + +  
Sbjct: 170 DQVINYVASQ-GQEFGFIHLSYFRPHPPFIAPAPYSEYYPEVNCQKP-EVDLETFLSMHP 227

Query: 250 WHPWTDVRK-RDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD--- 305
           +H     +  ++    L+      ++  +++ + +++YY     +D  +G L++++    
Sbjct: 228 FHECLFHQLYKNTFNNLSYKQIESILTERFS-RDKRAYYGLITELDYHLGRLITFLKDKG 286

Query: 306 -MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT-----VVHEPVEL 359
              +T+++ TSDHG  LG+  L+ K   FD +  VPL+ K PK + +     +V      
Sbjct: 287 VYDETLLIFTSDHGELLGDKWLYEKGGYFDQSFHVPLLIKPPKALRSKQEGKIVDSFTSS 346

Query: 360 IDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKS 394
           ID+ PT++D+  ++  IP+ +     ++L  +GK+
Sbjct: 347 IDLMPTILDI--INAPIPESVEGLSLAELLSDGKN 379



 Score = 42.7 bits (96), Expect = 0.022
 Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 5/61 (8%)

Query: 25 NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
          NI+ I +D +R      L +  +  PN++ L      F+N F+  + C+P+R SLLTG+ 
Sbjct: 3  NIILICVDQMRADTIRILGNPSIITPNLDALSLNSVVFSNHFSAGSPCSPARTSLLTGQY 62

Query: 80 P 80
          P
Sbjct: 63 P 63


>UniRef50_A6DKC5 Cluster: Putative sulfatase yidj; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Putative sulfatase yidj -
           Lentisphaera araneosa HTCC2155
          Length = 511

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 76/335 (22%), Positives = 130/335 (38%), Gaps = 38/335 (11%)

Query: 42  VYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGN 101
           V  P+I+ L + G   NN +A   +C+P+R S ++G+ P +  + D  ++  D      +
Sbjct: 69  VETPHIDKLAEEGVLCNNFYASSPVCSPARGSFISGQYPQNTPVIDNNTHMSD------D 122

Query: 102 FTTIPQFFKEHGYDTYSVGKVFHPGKSS-NFTDDYPYSWSEYPYHPPTEMYKDAKVCRNK 160
             +     + HGY T   GK    G     +  +  + + +  Y      +K      + 
Sbjct: 123 VVSFGSILQSHGYTTGYSGKWHLDGDGKPQWGPERQFGFEDNRYMFNRGHWKKILDTASG 182

Query: 161 KTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKF 220
                E+       V      +       +  IDF+ +   S PF   + +  PH P   
Sbjct: 183 PKIGAEKRGTPTYDVNGADENTYTTDWLTNKTIDFITQHKAS-PFCYMVSYPDPHGPDTV 241

Query: 221 PKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTL 280
              Y          +PK  +  +D  L SW                         TK   
Sbjct: 242 RAPYDTMYTHMNFQKPKTASKKQD-DLPSW-----------------------ATTKRGA 277

Query: 281 KIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYA 336
             +  YY     ID+ I  +++ +D    ++ TI+V TSDHG   GE+G   K    + +
Sbjct: 278 ANQSQYYGMIKCIDDNIARIMTCLDEQGILENTIVVFTSDHGDMRGEHGRQNKGIPLEAS 337

Query: 337 LKVPLIFKSPKLIPT--VVHEPVELIDIFPTLVDL 369
            KVP I + PK I +  +V+E +  +D  PT++ L
Sbjct: 338 AKVPFIVRYPKKISSGKIVNEALSGVDFLPTILGL 372


>UniRef50_A6DIH0 Cluster: Iduronate-2-sulfatase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Iduronate-2-sulfatase -
           Lentisphaera araneosa HTCC2155
          Length = 189

 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 30/67 (44%), Positives = 43/67 (64%), Gaps = 1/67 (1%)

Query: 307 QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPT-VVHEPVELIDIFPT 365
           + TI++L SDHGW LGE   W K S ++   +VP I K P +    ++++PV L DI+P+
Sbjct: 15  KNTIVILWSDHGWHLGEKEHWRKMSLWEQGTRVPFIIKMPGMKEAKLINDPVSLQDIYPS 74

Query: 366 LVDLTKL 372
           LVDL  L
Sbjct: 75  LVDLCNL 81


>UniRef50_A6DKP3 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;
           Lentisphaera araneosa HTCC2155|Rep:
           N-acetylgalactosamine 6-sulfatase - Lentisphaera
           araneosa HTCC2155
          Length = 465

 Score = 64.9 bits (151), Expect = 5e-09
 Identities = 58/214 (27%), Positives = 100/214 (46%), Gaps = 17/214 (7%)

Query: 25  NILFILIDDLR------HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           NI+ IL DDL       H + K+   P+I+ + ++GA F N ++   +C PSR  LL+GR
Sbjct: 24  NIIVILADDLGYGDVSYHGTLKETTTPHIDSIAQSGAWFQNGYSAAPVCGPSRAGLLSGR 83

Query: 79  RPDSLRLYDF---YSYWRDRSNGQG-NFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDD 134
                  YD    ++  +D   G   +   IP+   + GY T  VGK +H G    F   
Sbjct: 84  YQQRFGYYDNIGPFTLNKDVEAGLPLSQKLIPEILVKEGYATGMVGK-WHDGDQHKF--- 139

Query: 135 YPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVK-RQPGQSLPDLQSLDYAI 193
           +PY+     ++       +  V + +     E   +   + +    G+ + +    + A+
Sbjct: 140 WPYNRGFQEFYGFNNGAINNWVLKGENHTVDEWGAVHRENKRVENSGEYMTEAFGRE-AV 198

Query: 194 DFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQ 227
           +F+  R+ ++PFFL + F+  H PL+ PK Y  Q
Sbjct: 199 EFI-DRHKTEPFFLYLSFNAVHGPLQAPKSYTNQ 231


>UniRef50_A6DTP6 Cluster: Arylsulfatase; n=1; Lentisphaera araneosa
           HTCC2155|Rep: Arylsulfatase - Lentisphaera araneosa
           HTCC2155
          Length = 553

 Score = 64.5 bits (150), Expect = 6e-09
 Identities = 63/217 (29%), Positives = 94/217 (43%), Gaps = 21/217 (9%)

Query: 24  KNILFILIDDLRHLSDKKVY-----LPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           +N++ IL+DDL + SD   Y      P I+ LG  G      +   A C P+R SLLTG 
Sbjct: 21  QNVILILVDDLGY-SDLSSYGGEIQTPAIDSLGAKGIKMTQLY-NSARCCPTRASLLTGL 78

Query: 79  RPDSLRLYDFYSYWRDRSNGQGNFT----TIPQFFKEHGYDTYSVGKVFHPGKSSNFTDD 134
                 +  F +  + +   +G       TI    K  GY TY  GK    G      D 
Sbjct: 79  YSHKTGV-GFMTKDQGKPGYRGFLNDKCMTIASVLKGAGYKTYLAGKWHLKGLKGQ--DC 135

Query: 135 YPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAID 194
            P S     ++ P   Y D  +     +   E+       V ++PG+        DYA+ 
Sbjct: 136 LPTSRGFDRFYGPFHDYADFYMPELYHSMP-EKGF----KVNQRPGKFFASNAITDYALS 190

Query: 195 FLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYL-KQMP 229
           FL + R   KP+FL + ++ PH PL+ PK+ + K +P
Sbjct: 191 FLNEARQEEKPYFLYLAYNAPHFPLQAPKDLIDKYVP 227


>UniRef50_P50429 Cluster: Arylsulfatase B precursor; n=17;
           Eumetazoa|Rep: Arylsulfatase B precursor - Mus musculus
           (Mouse)
          Length = 534

 Score = 64.5 bits (150), Expect = 6e-09
 Identities = 60/237 (25%), Positives = 101/237 (42%), Gaps = 16/237 (6%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGAT 56
           ++ ++ ++LL       S    P +++F+L DDL           +  P+++ L   G  
Sbjct: 23  LLLLLQLLLLLLSPARASGATQPPHVVFVLADDLGWNDLGFHGSVIRTPHLDALAAGGVV 82

Query: 57  FNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDT 116
            +N + Q  LC PSR+ LLTGR    L L  +       S    +   +PQ  KE GY T
Sbjct: 83  LDNYYVQP-LCTPSRSQLLTGRYQIHLGLQHYLIMTCQPSCVPLDEKLLPQLLKEAGYAT 141

Query: 117 YSVGKVFHPGKSSNFTDDYPYSWSEY-PYHPPTEMYKDAKVCRNKKTKKLERNLICPVSV 175
           + VGK +H G            +  Y  Y   +E Y   + C   ++    R   C + +
Sbjct: 142 HMVGK-WHLGMYRKECLPTRRGFDTYFGYLLGSEDYYTHEACAPIESLNGTR---CALDL 197

Query: 176 K--RQPGQSLPDLQSLDY----AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLK 226
           +   +P +   ++ S +     A   +      KP FL + F   H PL+ P+EY++
Sbjct: 198 RDGEEPAKEYNNIYSTNIFTKRATTVIANHPPEKPLFLYLAFQSVHDPLQVPEEYME 254


>UniRef50_Q6SI01 Cluster: Sulfatase family protein; n=1; uncultured
           bacterium 106|Rep: Sulfatase family protein - uncultured
           bacterium 106
          Length = 533

 Score = 64.1 bits (149), Expect = 8e-09
 Identities = 56/222 (25%), Positives = 108/222 (48%), Gaps = 19/222 (8%)

Query: 190 DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRP-KEPNIPKD---M 245
           D  + +L  R  ++ FF  + +  PH P   P++Y      S+V +P +  ++ ++    
Sbjct: 194 DELLKWLSVRK-NESFFAHLSYLSPHPPWIAPEKYNNMYDPSEVPKPIRRESLEEEGRQH 252

Query: 246 PLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV- 304
           PL+      ++ +R       +  P  +M     L+ R +YY     +D  +G +++Y+ 
Sbjct: 253 PLLKM--LHELIQRSFFFNDKLIEPAAMMSDLDVLQARATYYGLMSQVDHHLGRVINYLK 310

Query: 305 ---DMQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHEPVELID 361
                  T+I+ TSDHG  LG++  + K   FD +  +PLI ++P++      + V    
Sbjct: 311 KSGQYDSTLIIFTSDHGEQLGDHYSFGKSGYFDQSYYIPLIIRTPEIAKQASKKSVGR-- 368

Query: 362 IFPTLVDL-TKLSDEIPKCLNHKDTS--QLCFEGKSLVPFIE 400
              T V+L T+  D +P  L+  +T   + C +G+SL+PF++
Sbjct: 369 --GTQVELFTEAIDVMPTILDWLETEIPEEC-DGRSLLPFLQ 407



 Score = 40.3 bits (90), Expect = 0.12
 Identities = 24/59 (40%), Positives = 28/59 (47%), Gaps = 5/59 (8%)

Query: 24 KNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTG 77
          KNILFI  D  R      +    V  PN++ L K G  F   + Q   C PSR SL TG
Sbjct: 6  KNILFITADQWRGDCLGCIGHPVVKTPNLDQLAKQGVLFRKHYTQTVPCGPSRASLFTG 64


>UniRef50_A6DJJ7 Cluster: Arylsulfatase; n=1; Lentisphaera araneosa
           HTCC2155|Rep: Arylsulfatase - Lentisphaera araneosa
           HTCC2155
          Length = 574

 Score = 64.1 bits (149), Expect = 8e-09
 Identities = 66/212 (31%), Positives = 87/212 (41%), Gaps = 33/212 (15%)

Query: 25  NILFILIDDLRHLSDKKVY-----LPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NIL +L DDL   SD   Y      P+I+ L K G  F       A C P+R SLLTG  
Sbjct: 62  NILLVLFDDLG-FSDLGCYGSEIRTPHIDRLAKKGLRFTG-MTNSARCVPTRGSLLTGLH 119

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFT----TIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY 135
           P    L           NG G       T+ +    HGY TY VGK +H G     TD  
Sbjct: 120 PGQAGLL----------NGSGKLVADCVTLAEVLGNHGYSTYGVGK-WHVGHLP--TDRG 166

Query: 136 PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDF 195
              +  YP     + +   +  R  + +K E        +K   G+        DYAI+F
Sbjct: 167 FDEFYGYPGGHSQDQWIQERYRRLPRGRKPE--------LKYDDGEFYATDVFTDYAIEF 218

Query: 196 L-KKRNGSKPFFLAIGFHKPHIPLKFPKEYLK 226
           + +     KP+FL +    PH PL  P E +K
Sbjct: 219 MGQAEKKRKPWFLYLAHSSPHFPLHAPIESVK 250



 Score = 35.1 bits (77), Expect = 4.4
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 8/83 (9%)

Query: 319 WSLGENGLWAKYSNFDY--ALKVPLIFKSPKL--IPTVVHEPVELIDIFPTLVDLTKLSD 374
           W+   N  +  Y +F +   +  P I   PK+  +   V +P  +ID+ PT++ L+    
Sbjct: 406 WANLGNTPYRMYKHFTHQGGIVTPFIIHWPKIEKVNRWVRDPAHIIDLMPTMLQLS--GA 463

Query: 375 EIPKCLNHKDTSQLCFEGKSLVP 397
           + PK  N  D   +  EG SLVP
Sbjct: 464 KYPKRYNDNDIQPM--EGVSLVP 484


>UniRef50_UPI00015B5C4D Cluster: PREDICTED: similar to
           ENSANGP00000018435; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000018435 - Nasonia
           vitripennis
          Length = 710

 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 61/208 (29%), Positives = 98/208 (47%), Gaps = 14/208 (6%)

Query: 18  SDVETPKNILFILIDDLR------HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSR 71
           S  E+P NI+ I+ DD+       H SD+ +  PNI+ L   G   N+ +   ALC PSR
Sbjct: 38  SSSESPPNIVMIIADDMGWNDVSFHGSDQ-IPTPNIDALAYNGVILNSHYVS-ALCTPSR 95

Query: 72  NSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG-KSSN 130
           ++LLTG+ P    +        +      +   +PQ+ KE GY T+++GK +H G     
Sbjct: 96  SALLTGKYPIHTGMQHLVILEAEPRGLPLHEKILPQYLKEAGYATHAIGK-WHQGFHRRE 154

Query: 131 FTDDYPYSWSEYPYHPPTEMYKDAKV-CRNKKTKKLERNLICPVSVKRQP-GQSLPDLQS 188
           +T  Y    S + Y    + Y   +V   N K   L  ++   +S+ R   G+   DL +
Sbjct: 155 YTPTYRGFDSHFGYWQGLQDYYTHEVGSSNPKEGFLGFDMRRNMSLARDTYGKYSTDLFT 214

Query: 189 LDYAIDFLKK-RNGSKPFFLAIGFHKPH 215
            D A+  +++ R  + P FL +    PH
Sbjct: 215 -DEAVRLIEEHRPEAGPMFLYLAHLAPH 241


>UniRef50_A6DNH2 Cluster: Putative uncharacterized protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Putative
           uncharacterized protein - Lentisphaera araneosa HTCC2155
          Length = 459

 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 56/241 (23%), Positives = 113/241 (46%), Gaps = 24/241 (9%)

Query: 185 DLQSLDYAIDFLKKR-NGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPK 243
           D+++   A  FL+K    SKPFFL +   +PH+PL +P++    +      +     + +
Sbjct: 154 DVETFKRANSFLQKAAKSSKPFFLWLAPRQPHLPL-YPQQKWLDLYNENELKLDANYLEE 212

Query: 244 DMPLVSWH---PWTDVRKRDDIRRLNITFPFGVMPTKWTLK-IRQSYYAAALYIDELIGI 299
            +P   ++   P  +  +  +  ++    P G    + T++   ++YYA   ++D  +G 
Sbjct: 213 PLPSSVFNQGKPGENFHRDSNYTKVWKKLPGGPPRNEATMRSFIKAYYAVISHLDSQVGQ 272

Query: 300 LLSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIPTVVHE 355
           ++  ++       T+IV  SD+G+ LG +GL  K +  + +++VP+     +L       
Sbjct: 273 MIENMEQLGIKDNTVIVFLSDNGYHLGNHGLGNKITMHEESVRVPMFINWSQLTSKGKRS 332

Query: 356 P--VELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEAFAISQ 413
              V  +D++P+L+DL  +   +P   NH         GKSL+P  ++    +     S+
Sbjct: 333 DALVSSLDLYPSLLDLAGV--PLP---NH-------LMGKSLLPIFKDEKANVRQVVFSE 380

Query: 414 C 414
           C
Sbjct: 381 C 381



 Score = 36.3 bits (80), Expect = 1.9
 Identities = 34/148 (22%), Positives = 62/148 (41%), Gaps = 10/148 (6%)

Query: 22  TPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTG 77
           T  NIL I  DD  +     ++  V  P+++ L + G   NN +    +C  SR ++++G
Sbjct: 27  TKPNILVIFTDDQVYRAIAYNNPAVKTPHLDKLAREGLILNNVYVASPICTASRAAMMSG 86

Query: 78  RRP--DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY 135
             P  + +   +  ++ +  +  +    ++P+  K+ GY     GK  H G   ++  D 
Sbjct: 87  VYPQQNGVVALNHKAFKKYYAGAERAEQSLPRQMKKAGYHCAFWGK-SHIGPPKSYGFD- 144

Query: 136 PYSWSEYPYHPPTEMYKDAKVCRNKKTK 163
                E   H   E +K A     K  K
Sbjct: 145 --EGEETKGHDDVETFKRANSFLQKAAK 170


>UniRef50_A0YAF7 Cluster: Arylsulfatase A; n=1; marine gamma
           proteobacterium HTCC2143|Rep: Arylsulfatase A - marine
           gamma proteobacterium HTCC2143
          Length = 479

 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 62/227 (27%), Positives = 100/227 (44%), Gaps = 21/227 (9%)

Query: 8   ILLNGDRVLTSDVETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFA 62
           +LL+   V     ++P N++ I  DD+ +          +  PN++ +   G  + N +A
Sbjct: 23  LLLSAYAVANPSHQSP-NVIIIFADDMGYGDIGAYGHPTIRSPNLDQMAAEGIKWTNFYA 81

Query: 63  QQALCAPSRNSLLTGRRP-DSLRLYDFYSYWRDRSNGQGNFT--TIPQFFKEHGYDTYSV 119
             ++C PSR  LLTGR P  S   +D        S G    T  TI +  KE  Y T  V
Sbjct: 82  ASSVCTPSRAGLLTGRLPVRSGMAHDQIRVLFPTSTGGLPTTEITIAKALKEKDYRTALV 141

Query: 120 GKVFHPGKSSNFTDDYPYSWSEY---PYHPPTEMYKDAKVCRNKKTKKLERNLICPVS-- 174
           GK +H G    F     + + EY   PY    ++ K+    +   T   + +   P+   
Sbjct: 142 GK-WHLGHLPGF-QPLDHGFDEYFGIPYSNDHDLKKELSYIQT-ITHAKDGDFNVPLMQN 198

Query: 175 ---VKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPL 218
              ++R   Q+    +    A+ F+KK N ++PFFL +    PH+PL
Sbjct: 199 RSIIERPANQNTITKRYTQEAVSFIKK-NSNQPFFLYLAHSMPHVPL 244



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 13/115 (11%)

Query: 293 IDELIGILLSYVDMQ----KTIIVLTSDHG-WSL-----GENGLW--AKYSNFDYALKVP 340
           ID  +G +LS +  Q     T++V TSD+G W +     G  GL    K ++++  ++ P
Sbjct: 266 IDWSVGQVLSTLSEQGISENTLVVFTSDNGPWLIMGAHGGSAGLLKSGKGTSYEGGMREP 325

Query: 341 LIFKSP-KLIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKS 394
            IF  P K+ P V H     +D+FPT++ +  +     +  +  D S   FE KS
Sbjct: 326 AIFWWPEKIKPAVAHNTASTLDLFPTIMSIAGIDMPSDRSYDGYDLSPTMFEQKS 380


>UniRef50_Q5DYR9 Cluster: N-acetylglucosamine-6-sulfatase; n=10;
           Gammaproteobacteria|Rep: N-acetylglucosamine-6-sulfatase
           - Vibrio fischeri (strain ATCC 700601 / ES114)
          Length = 518

 Score = 63.3 bits (147), Expect = 1e-08
 Identities = 98/404 (24%), Positives = 158/404 (39%), Gaps = 62/404 (15%)

Query: 16  LTSDVETPKNILFILIDDLR-----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPS 70
           L   ++ P N+L I  D++R      + +     PN+N   K  A    A +   LC P 
Sbjct: 39  LAHKIKRP-NLLIIFPDEMRAQALGFMGEDPSLTPNLNRFAKDSAVLKQAVSNFPLCTPF 97

Query: 71  RNSLLTGRRPDSLRLY-DFYSYWRDRSNGQG-------NFTTIPQFFKEHGYDTYSVGKV 122
           R  L+TG+ P    +  + ++       G+        N +T      + GY    +GK 
Sbjct: 98  RGMLMTGQYPYRNGIQGNSHTATPGMFGGKDFGIELKKNQSTWSDILSQQGYSMGYIGKW 157

Query: 123 FHPGKSSNFTDDY--PYS---WSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKR 177
                 + F   Y  P     W+++   P      D         K L        + + 
Sbjct: 158 HLDAPEAPFVPSYNNPMEGRYWNDWTT-PDRRHGFDFWYSYGTYDKHLTPMYWTNDTPRD 216

Query: 178 QP---GQSLPDLQSLDYAIDFLKKRNGS-----KPFFLAIGFHKPHIPLKFPKEYLKQMP 229
           QP    Q  P+ ++ D AI +L+  NG+     KPF L +  + PH P         Q+P
Sbjct: 217 QPLHINQWSPEHEA-DIAIKYLRNENGNYRNNDKPFTLVVSMNPPHSPYD-------QVP 268

Query: 230 ISKVHRPKEPNIP-KDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYA 288
              + R KE +      P V W          D   L      G  P  +     + Y A
Sbjct: 269 QKYLDRFKESSRTLNSRPNVQW----------DKEYLE-----GYGPEYF-----KEYMA 308

Query: 289 AALYIDELIGILLSYVDM----QKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFK 344
               +DE  G ++  +D     + T++V  SDHG  +G NG   K  +++ A+++P++F+
Sbjct: 309 MVNGVDEQFGRIVDELDALNLAKDTLVVFFSDHGCCMGSNGNPTKNVHYEEAMRIPMMFR 368

Query: 345 SP-KLIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQ 387
            P K+ P          DI+PTL  L  + D IP  +   D S+
Sbjct: 369 WPGKIAPKSDDLLFSAPDIYPTLFGLMGMDDLIPDTVEGTDFSK 412


>UniRef50_Q45087 Cluster: Phosphonate monoester hydrolase; n=4;
           Proteobacteria|Rep: Phosphonate monoester hydrolase -
           Burkholderia caryophylli
          Length = 514

 Score = 63.3 bits (147), Expect = 1e-08
 Identities = 59/215 (27%), Positives = 95/215 (44%), Gaps = 21/215 (9%)

Query: 192 AIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWH 251
           A+ +LK R+G KPFFL +G+++PH P      Y        +  P     P      + H
Sbjct: 196 ALTYLKGRDG-KPFFLHLGYYRPHPPFVASAPYHAMYKAEDMPAPIRAENPDAE--AAQH 252

Query: 252 PWTDVRKRDDIRRLNITFPFGVMPTKWTL------KIRQSYYAAALYIDELIGILLSYVD 305
           P       D IRR +  F  G   +  TL      ++R +Y      ID+ +G + +Y+D
Sbjct: 253 PLMK-HYIDHIRRGS--FFHGAEGSGATLDEGEIRQMRATYCGLITEIDDCLGRVFAYLD 309

Query: 306 ----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP---KLIPTVVHEPVE 358
                  T+I+ TSDHG  LG++ L  K      + ++PL+ K     +    +     E
Sbjct: 310 ETGQWDDTLIIFTSDHGEQLGDHHLLGKIGYNAESFRIPLVIKDAGQNRHAGQIEEGFSE 369

Query: 359 LIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGK 393
            ID+ PT+++   L  E P+  + +       EGK
Sbjct: 370 SIDVMPTILEW--LGGETPRACDGRSLLPFLAEGK 402



 Score = 36.3 bits (80), Expect = 1.9
 Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 10/66 (15%)

Query: 22 TPKNILFILIDDLR-----HL---SDKKVYL--PNINFLGKTGATFNNAFAQQALCAPSR 71
          T KN+L I++D  R     HL     ++ +L  PN++ L + G TF N       C P+R
Sbjct: 2  TRKNVLLIVVDQWRADFIPHLMRAEGREPFLKTPNLDRLCREGLTFRNHVTTCVPCGPAR 61

Query: 72 NSLLTG 77
           SLLTG
Sbjct: 62 ASLLTG 67


>UniRef50_A6DHI0 Cluster: N-acetylgalactosamine 6-sulfate sulfatase;
           n=1; Lentisphaera araneosa HTCC2155|Rep:
           N-acetylgalactosamine 6-sulfate sulfatase - Lentisphaera
           araneosa HTCC2155
          Length = 456

 Score = 63.3 bits (147), Expect = 1e-08
 Identities = 58/207 (28%), Positives = 90/207 (43%), Gaps = 22/207 (10%)

Query: 25  NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NI+FI+ DD+ +        K +  P ++ + K G    + +A  A+CAPSR SL+TG+ 
Sbjct: 21  NIIFIMCDDMGYGQLGSYGQKMIKTPRLDQMAKEGLRLTDYYAGTAVCAPSRCSLMTGQH 80

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK--VFHPGKSSN-FTDDYP 136
                +     Y   +        T+ +  KE GY T  +GK  + +PG         + 
Sbjct: 81  VGHTYIRGNKEYPTGQEPIPAETITVAEKMKEAGYATALIGKWGLGYPGSEGEPNKQGFD 140

Query: 137 YSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSL--DYAID 194
           Y +           Y D K   N   K L RN    +++K   G+ +   Q +  D A  
Sbjct: 141 YFFG----------YNDQKHAHNHFPKFLLRNEE-TLTLKNNSGKEIEYSQYMLTDEAKG 189

Query: 195 FLKKRNGSKPFFLAIGFHKPHIPLKFP 221
           F+KK N   PFFL + +  PH  L+ P
Sbjct: 190 FIKK-NKDNPFFLYLAYVIPHSRLQIP 215


>UniRef50_Q650Q8 Cluster: Arylsulfatase; n=5; Bacteria|Rep:
           Arylsulfatase - Bacteroides fragilis
          Length = 537

 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 62/220 (28%), Positives = 94/220 (42%), Gaps = 18/220 (8%)

Query: 13  DRVLTSDVETPKNILFILIDDL--RHLS--DKKVYLPNINFLGKTGATFNNAFAQQALCA 68
           DR    D   P NI+ I+ DD+    LS    +V+ P+I+FL + G  F+  F       
Sbjct: 26  DRKANPDQAKP-NIILIMCDDMGFSDLSCYGGEVHTPHIDFLAENGIRFSQ-FKNTGRSC 83

Query: 69  PSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGN----FTTIPQFFKEHGYDTYSVGKVFH 124
           PSR +LLTGR    + +    +    R   +G     + TI + F+E+GY TY  GK +H
Sbjct: 84  PSRAALLTGRYQHEVGMGWMTAVDEHRPGYRGQISDRYPTIAEVFRENGYHTYMSGK-WH 142

Query: 125 PGKSSNFTDDYPYSWSEYPYHPPTEMYKDA-KVCRNKKTKKLERNLICPVSVKRQPGQSL 183
                 FT         YP     E Y        N  T K   + +    +   P    
Sbjct: 143 VTVEGAFTQPN----GSYPVERGFEKYYGCLSGGGNYYTPKPVFSGL--QRITEFPKDYY 196

Query: 184 PDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKE 223
                 D A+ F+++    +P F+ +  + PH+PL+ PKE
Sbjct: 197 YTTAITDSAVSFIRQHPVDEPMFMYLAHYAPHLPLQAPKE 236


>UniRef50_A0M223 Cluster: Sulfatase; n=1; Gramella forsetii
           KT0803|Rep: Sulfatase - Gramella forsetii (strain
           KT0803)
          Length = 572

 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 89/358 (24%), Positives = 149/358 (41%), Gaps = 45/358 (12%)

Query: 45  PNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTT 104
           P ++ L + G  F+NAF   ++C PSR ++LTG+R  +  + D                 
Sbjct: 75  PVLDSLARDGMIFDNAFVNNSICVPSRAAILTGQRAQTNGVIDLEGTLPVEKQ------Y 128

Query: 105 IPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNK--KT 162
           +P+   + GY T  VGK +H        D Y     +  Y  P    +  K       KT
Sbjct: 129 LPKEMSKLGYQTALVGK-WHLHDEPAAFDYYQVLPVQGKYFDPDFRVRGEKSWPQNVIKT 187

Query: 163 KKLERNLICPVSV-----KRQPGQSL----------PDLQSLDYAIDFLKKRNGSKPFFL 207
           K    ++I  +S+     KR P +             D +      D+LK     +P  +
Sbjct: 188 KGHSTDIITDISLDWLKNKRDPNKPFFLMHHFKAPHDDFEHAPRYEDYLKNAFIPEPASM 247

Query: 208 AIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRK--RD----D 261
                   I  +   + L ++  S V R    N+ ++  + + +P  ++ K  RD    D
Sbjct: 248 YYNADNGSIATRGVHDSLTRIIGSSVSRR---NLVRNQAM-NIYPEKEIYKNYRDAGDID 303

Query: 262 IRRLNITFPFGVMPTKWTLKIRQSY---YAAALY-IDELIGILLSYVD----MQKTIIVL 313
           I   +I F       K+T  + Q Y   Y  A+  +D+ +  LL Y++    M+ TIIV 
Sbjct: 304 ISE-HIPFELDAEERKYTSAVYQDYLKKYLRAVKGVDDNVKRLLDYLEQEGLMENTIIVY 362

Query: 314 TSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVHEPVELIDIFPTLVDL 369
           T D G+ LGE+    K   +D ++++P   + PK I   T  +  +   D  PTL++L
Sbjct: 363 TGDQGFMLGEHDYIDKRWMYDESMRMPFFVRYPKTIQAGTRTNAIINNTDFAPTLIEL 420


>UniRef50_A0JVM4 Cluster: Sulfatase; n=1; Arthrobacter sp. FB24|Rep:
           Sulfatase - Arthrobacter sp. (strain FB24)
          Length = 479

 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 95/373 (25%), Positives = 155/373 (41%), Gaps = 66/373 (17%)

Query: 25  NILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NIL IL DD     L    + ++  P+++ L   G   +N F    +C+P+R SL+TG  
Sbjct: 8   NILLILSDDQGAWALGCSGNTEIQTPHLDNLASGGTRLDNFFCVSPVCSPARASLMTGTI 67

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEH----GYDTYSVGKVFHPGKSSNFTDDY 135
           P    ++D Y +  +      ++    + F +     GY     GK +H G +    + +
Sbjct: 68  PSKHGVHD-YLHGVETGPEAPDYLQGQRLFTDDLAAAGYYMGLSGK-WHLGANDRAREGF 125

Query: 136 PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDF 195
            + +S      P   Y  A + RN               VK      L D  + D +  F
Sbjct: 126 SHWFSLAGGGSP---YDAATMYRN--------------GVKETVYGYLTDAITAD-STGF 167

Query: 196 LKKRNGS-KPFFLAIGFHKPHIPLK--FPKEYLKQMPISKVHR-PKEPNIPKDMPLVSWH 251
           +++  G   PFFLA+ +  PH P K   P E+            P+EP           H
Sbjct: 168 MERAAGQDSPFFLALNYTAPHKPWKDQHPAEFTALYDDCAFESCPQEPT----------H 217

Query: 252 PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQ 307
           PWT     D +       P G         +   Y+AA   +D  IG +L  +D     +
Sbjct: 218 PWTPTV--DGV-------PIGGEADVRAALV--GYFAAVSAMDAGIGQVLQKLDELGLRE 266

Query: 308 KTIIVLTSDHGWSLGENGLWAKYSN------FDYALKVPLIFKSPKLIP--TVVHEPVEL 359
            T+++ +SD+G++ G++G+W K +       FD ++KVP IF  P  I    V  E +  
Sbjct: 267 DTLVIFSSDNGFNCGQHGVWGKGNGTFPLNVFDSSIKVPAIFSFPGRIARGKVREELLSA 326

Query: 360 IDIFPTLVDLTKL 372
            D+  T+++L  L
Sbjct: 327 YDLPATILELAGL 339


>UniRef50_Q127E2 Cluster: Sulfatase; n=1; Polaromonas sp. JS666|Rep:
           Sulfatase - Polaromonas sp. (strain JS666 / ATCC
           BAA-500)
          Length = 511

 Score = 62.5 bits (145), Expect = 3e-08
 Identities = 54/196 (27%), Positives = 87/196 (44%), Gaps = 23/196 (11%)

Query: 190 DYAIDFLKKRNG--SKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPL 247
           D  I+F++K  G  +K F L   F  PH P   P+      P S++H P E ++P     
Sbjct: 207 DRTIEFMRKHAGEAAKRFCLWASFPDPHHPFDCPE------PWSRLHHPDEVDLPAHRTT 260

Query: 248 -VSWHPW-----TDVRKRDDIRRLNITFPFGVMPTKWTLKIRQ---SYYAAALYIDELIG 298
                PW      D +   D     +   F  MPT    ++R    +YY     +D  +G
Sbjct: 261 DFERRPWWHKASMDSKPVGDAAVQALRQNFSRMPTPAEQQLRNITANYYGMISLVDHQVG 320

Query: 299 ILLSYVDMQ----KTIIVLTSDHGWSLGENGLWAKYS-NFDYALKVPLIFKSPKL-IPTV 352
            + + +        T+++ TSDHG  LG++GL  K    ++  L+V ++   P++    V
Sbjct: 321 RIQTALQQLGLDGNTLVIFTSDHGEWLGDHGLMLKGPIPYEGVLRVGMVVNGPQVQAGQV 380

Query: 353 VHEPVELIDIFPTLVD 368
            HEPV  +D+  T  D
Sbjct: 381 RHEPVSTLDLAATFAD 396



 Score = 41.9 bits (94), Expect = 0.039
 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 8/101 (7%)

Query: 25  NILFILID----DLRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           NIL I  D    D    + +KV  P+I+ + +TG  F +      +C PSR S+LTG  P
Sbjct: 5   NILLITTDQHRGDCLGFAGRKVKTPHIDEMARTGTHFTSCITPNIVCQPSRASILTGLLP 64

Query: 81  DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK 121
            +  + D      D + G+  F          GY T  +GK
Sbjct: 65  LTHGVCD-NGIDLDEARGEAGFAGT---LASSGYSTGFIGK 101


>UniRef50_A3I1P8 Cluster: Heparan N-sulfatase; n=3; Bacteria|Rep:
           Heparan N-sulfatase - Algoriphagus sp. PR1
          Length = 549

 Score = 62.5 bits (145), Expect = 3e-08
 Identities = 95/362 (26%), Positives = 156/362 (43%), Gaps = 77/362 (21%)

Query: 25  NILFILIDDLRHL-----SDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NILF ++DD+ ++       + V  PN + + K G  F NA+   A C PSR+++LTGR 
Sbjct: 33  NILFAIMDDVTYMHMGAYGCEWVNTPNFDRIAKEGILFQNAYTPNAKCGPSRSNILTGR- 91

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
            +S +L +  ++W   S     F +  +   EHG   Y VG   + GK           W
Sbjct: 92  -NSWQLEEGANHW---SYFPSKFKSFAESLSEHG---YHVG---YTGKG----------W 131

Query: 140 SEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDF---L 196
           +           +D  V R  + K     L  P +          ++ ++DYA +F   L
Sbjct: 132 APGVAKNEDGSARDLLVNRYSEIK-----LTAPTA----------NISNVDYAANFDVFL 176

Query: 197 KKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDV 256
           K RN  +PFF   G  +PH      + Y     I+K    KE +  KD  + S+ P    
Sbjct: 177 KDRNEDEPFFFWYGGLEPH------RGYEYGSGIAK--GGKEVSQIKDEDIYSFWP---- 224

Query: 257 RKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTSD 316
            K D +R   + + F +            ++   L   +++  L +  +++ T+IV+TSD
Sbjct: 225 -KVDSVRTDLLDYAFEI-----------EHFDKQL--GKMLDQLEAAGELENTLIVVTSD 270

Query: 317 HGWSLGENGLWAKYSNFDYALKVPLIFKSP---KLIPTVVHEPVELIDIFPTLVDLTKLS 373
           +G          K   ++Y+  +PL    P   K I   V + V  ID  PT ++L  +S
Sbjct: 271 NGMPFPR----VKGQEYEYSNHLPLAVMWPAGIKSIGRTVEDFVSFIDFAPTFLELAGVS 326

Query: 374 DE 375
           +E
Sbjct: 327 EE 328


>UniRef50_A0LYA0 Cluster: Sulfatase; n=3; Bacteria|Rep: Sulfatase -
           Gramella forsetii (strain KT0803)
          Length = 566

 Score = 62.5 bits (145), Expect = 3e-08
 Identities = 75/260 (28%), Positives = 114/260 (43%), Gaps = 46/260 (17%)

Query: 253 WTDVR--KRDDIRRLNITFPFGVMPTKWT-LKIRQSYYAAALYIDELIGILLSYVDMQ-- 307
           W D    K D     N+T   G    +W   +  + Y      +DE +G +L Y++ Q  
Sbjct: 296 WNDAYRPKNDAFHDANLT---GKDLAEWKGQRYLRDYMGTVAAVDEGVGKILDYLEEQGL 352

Query: 308 --KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKLIP--TVVHEPVELIDIF 363
              TIIV T+D G+ LGE G++ K   ++ +L +PL+ + PK I   T +    + +D  
Sbjct: 353 TENTIIVYTTDQGFYLGEKGMFDKRFMYEESLAMPLLIQYPKGIKKGTTIDALTQNLDFA 412

Query: 364 PTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIE-NNSNGLEAFAISQCPRPSVYPQ 422
           PT +D      EIP+ +          +GKSL P +  NN +G   F      R +VY  
Sbjct: 413 PTFLDFA--GAEIPESM----------QGKSLRPLLSGNNPDG--NF------RDAVY-Y 451

Query: 423 KNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXXXXXXXXXXYGIELYDHIIDPIESKN 482
              D P    +    Y +RT+RY+   +                  ELYD   DP E  N
Sbjct: 452 HYYDFPAFHMVK-RHYGVRTERYKLIHFYDDIDTW-----------ELYDLKEDPKEEIN 499

Query: 483 LFLVSKYKNIAKVLSIRLRS 502
           L+   +Y+ I K L  +L+S
Sbjct: 500 LYGSVEYEEIQKNLHEKLKS 519



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 42/144 (29%), Positives = 66/144 (45%), Gaps = 16/144 (11%)

Query: 18  SDVETPKNILFILIDD--------LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAP 69
           S+ + P NI+FI+ DD          H   +K   PNI+ +   GA F N F   ++C P
Sbjct: 38  SEAKRP-NIVFIMTDDHAAQAISAYGHPVSQKAPTPNIDRIANNGAKFLNNFCTNSICGP 96

Query: 70  SRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSS 129
           SR  +LTG      +      +  +     G+  T+P++ K+ GY T  VGK    GK  
Sbjct: 97  SRAVILTG------KFSHINGFRMNGETFDGSQPTLPKYLKKAGYQTAIVGKWHLHGKPQ 150

Query: 130 NFTDDYPYSWSEYPYHPPTEMYKD 153
            F D +     +  Y+ P  ++K+
Sbjct: 151 GF-DYWNILKDQGNYYNPEFIHKN 173


>UniRef50_Q8FTJ9 Cluster: Putative arylsulfatase; n=1;
           Corynebacterium efficiens|Rep: Putative arylsulfatase -
           Corynebacterium efficiens
          Length = 611

 Score = 62.1 bits (144), Expect = 3e-08
 Identities = 63/215 (29%), Positives = 99/215 (46%), Gaps = 27/215 (12%)

Query: 25  NILFILIDDLRHLSDKKVY-----LPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NI+ IL+DDL + SD   Y      PNI+ L + G  F N F    LCAP+R +L+TG+ 
Sbjct: 66  NIMMILLDDLGY-SDLGAYGGEAETPNIDALAQEGVQFTN-FHATPLCAPTRAALMTGQD 123

Query: 80  PDSLRLYDFYSYW-----RD----RSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSN 130
           P  + L            +D    + + +G+FT I +   + GYDTY VGK +H G+ + 
Sbjct: 124 PHRVGLGSMEGMAPPGVDQDTPGYKGSLEGDFTGIAEVLSDTGYDTYQVGK-WHLGREAE 182

Query: 131 FTDD-YPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPD--LQ 187
                  +  +   Y      Y DA    N+  + +  N +       +   +LPD    
Sbjct: 183 QRPSALGFDENFTMYDAGASYYPDALRLFNRPVEPV--NTVV-YERNGETLDTLPDDFFA 239

Query: 188 SLDYAIDFLKKRNGS----KPFFLAIGFHKPHIPL 218
           +  Y  + L++ + S    +PFF  +G+  PH PL
Sbjct: 240 TRSYTDEVLQQVDQSVEADQPFFTYLGYTAPHDPL 274


>UniRef50_A3XJJ9 Cluster: Arylsulfatase B; n=1; Leeuwenhoekiella
           blandensis MED217|Rep: Arylsulfatase B -
           Leeuwenhoekiella blandensis MED217
          Length = 461

 Score = 62.1 bits (144), Expect = 3e-08
 Identities = 64/222 (28%), Positives = 101/222 (45%), Gaps = 19/222 (8%)

Query: 11  NGDRVLTSDVETPKNILFILIDDLR----HLSDKKVYLPNINFLGKTGATFNNAFAQQAL 66
           N D++L  D +TP N L I+ DD           ++  PN++ L   G T +  F     
Sbjct: 28  NKDKIL-DDKKTP-NFLVIIADDAGWNDFSFHGSEIQTPNLDQLAGKGLTLDR-FYTYPT 84

Query: 67  CAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG 126
           C+P+R SLLTGR    + +    S  R   N   + TT+PQ   +  Y T  +GK +H G
Sbjct: 85  CSPARASLLTGRPASRMGIVAPIS-GRSELNLPDSITTLPQALSKLNYKTALMGK-WHLG 142

Query: 127 -KSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPD 185
            K  +  + Y + +S    H   + Y  A   +N  +          +S K      L  
Sbjct: 143 LKPESGPEVYGFDFSYGFLHGQLDQY--AHTYKNGDSTWYRNGKF--ISEKGHVTDLLT- 197

Query: 186 LQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQ 227
            QS  + ID L+     + F+L + +  PHIPL+ P+E+L++
Sbjct: 198 -QSAVHYIDTLQT---DQNFYLQVAYSAPHIPLQEPQEWLEK 235


>UniRef50_Q1VP00 Cluster: Arylsulfatase B; n=1; Psychroflexus
           torquis ATCC 700755|Rep: Arylsulfatase B - Psychroflexus
           torquis ATCC 700755
          Length = 386

 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 47/137 (34%), Positives = 70/137 (51%), Gaps = 14/137 (10%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDDLRHLSDKKVY-----LPNINFLGKTGA 55
           M+++   +LL G   +TS  E P NIL I  DD + ++D   Y      PNI+ +G  G 
Sbjct: 1   MLFLRISLLLLGFSTITSGAERP-NILLIFTDD-QGINDVGCYGSEIPTPNIDRIGAEGI 58

Query: 56  TFNNAFAQQALCAPSRNSLLTGRRP--DSLRLYDFYSYWRDRSNG---QGNFTTIPQFFK 110
            F N ++  ++C PSR  LLTGR P     +L     +  D   G   + + TTI +  +
Sbjct: 59  QFRNFYSASSICTPSRFGLLTGRNPIRSQDQLLSALMFMADEHKGYSIKPHETTIAEVLR 118

Query: 111 EHG-YDTYSVGKVFHPG 126
           + G YDT  +GK +H G
Sbjct: 119 DEGAYDTALIGK-WHLG 134


>UniRef50_A7LZQ6 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides ovatus ATCC 8483|Rep: Putative
           uncharacterized protein - Bacteroides ovatus ATCC 8483
          Length = 505

 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 45/120 (37%), Positives = 64/120 (53%), Gaps = 8/120 (6%)

Query: 21  ETPKNILFILIDDLRH--LS----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSL 74
           +TP NI+FIL DDL +  +S    + K++ PNI+ L + G  F +A A  AL  PSR SL
Sbjct: 20  QTP-NIVFILADDLGYGDISAFNPESKIHTPNIDKLAEHGIAFTDAHASSALSTPSRYSL 78

Query: 75  LTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDD 134
           LTGR P   +L          +       TI Q F  +GY+T  +GK +H G    +T++
Sbjct: 79  LTGRYPWRTKLKRGGLDGDSPAMIDPERRTIAQMFSANGYNTACIGK-WHLGWDWGYTNN 137


>UniRef50_A0JVN2 Cluster: Sulfatase; n=1; Arthrobacter sp. FB24|Rep:
           Sulfatase - Arthrobacter sp. (strain FB24)
          Length = 449

 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 53/189 (28%), Positives = 86/189 (45%), Gaps = 16/189 (8%)

Query: 192 AIDFLKKRNGS-KPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKE----PNIPKDMP 246
           AID+L  R+ +  PF L + F  PH   ++ +   + +P   V RP +    P +P +  
Sbjct: 138 AIDWLGARHDTGTPFLLLVSFDNPHTICEYARG--QHLPYGDVQRPADIRDAPPLPSNFA 195

Query: 247 LVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM 306
              + P     +R    +   T  F      W L  R +Y       DE IG++L  +D 
Sbjct: 196 TTPYSPQALTHERAQAEQAYGTADFS--HDDWRL-YRHAYAQLIERTDEQIGVILGELDR 252

Query: 307 Q----KTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKL-IPTVVHEPVEL-I 360
           Q     T+++ TSDHG     +G   K S  + A++VPL+ + P +    V  + + L +
Sbjct: 253 QGLRETTVVLFTSDHGDGDAAHGWNQKTSLQEEAIRVPLLMRGPGVGYSQVGSQLISLGL 312

Query: 361 DIFPTLVDL 369
           D+ PTL  L
Sbjct: 313 DLIPTLCSL 321



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 4/95 (4%)

Query: 42  VYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGN 101
           V  PN++ L   G  F+ A+    LC P+R+SL++GR P  L + D  +      +G G 
Sbjct: 32  VNTPNLDNLAAAGTRFDRAYTTFPLCVPARSSLVSGRYPHELGI-DGNAV--PAGSGPGR 88

Query: 102 FT-TIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY 135
              ++  +FK  GYD    GK   P  S+   D +
Sbjct: 89  TPGSLGHWFKAAGYDCAYAGKWHAPEASAQPEDGF 123


>UniRef50_Q7UH63 Cluster: Arylsulphatase A; n=3; Bacteria|Rep:
           Arylsulphatase A - Rhodopirellula baltica
          Length = 491

 Score = 61.3 bits (142), Expect = 6e-08
 Identities = 56/215 (26%), Positives = 95/215 (44%), Gaps = 20/215 (9%)

Query: 25  NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N + +L DDL +          +  PN+N L  TG    N ++   +C+PSR  LLTGR 
Sbjct: 30  NFVIVLCDDLGYGDLECFGHPHIKTPNLNQLAATGIRLTNCYSAAPVCSPSRVGLLTGRS 89

Query: 80  PDSLRLYDFYSY-------WRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFT 132
           P+   +YD+           RD+ + + +  TI Q   + GY T   GK +H   +S F 
Sbjct: 90  PNRAGVYDWIPEARNPRPDARDQVHMRDHEITIAQLLNDAGYATCMAGK-WH--CNSRFN 146

Query: 133 DDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYA 192
           D       ++ +        +A    ++  K   RN   P+    +        ++L + 
Sbjct: 147 DPAQPQPDDFGFDHYLATQNNA-APSHQFPKNFVRN-GKPIGKVDEFSCQFVVTEALQW- 203

Query: 193 IDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQ 227
           +D  ++    +PFFL + FH+PH P+  P+  + Q
Sbjct: 204 LD--RRSEKDQPFFLYLPFHEPHEPVASPEALVAQ 236


>UniRef50_A6CGG6 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;
           Planctomyces maris DSM 8797|Rep: N-acetylgalactosamine
           6-sulfatase - Planctomyces maris DSM 8797
          Length = 461

 Score = 61.3 bits (142), Expect = 6e-08
 Identities = 60/219 (27%), Positives = 103/219 (47%), Gaps = 21/219 (9%)

Query: 17  TSDVETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPS 70
           T+  +T  N+L IL+DDL +  D   Y       P+I+ L   G  F+N +A   +C+P+
Sbjct: 26  TTAQQTRPNVLVILVDDLGY-GDLSSYGATDLKSPHIDELLNRGMKFSNFYANCPVCSPT 84

Query: 71  RNSLLTGRRPDSLRLYDFYSYWRDRSNG--QGNFTTIPQFFKEHGYDTYSVGKVFHPG-K 127
           R +LLTG   D + +        + S G  + +  T+   F   GY T  +GK +H G +
Sbjct: 85  RAALLTGHYQDMVGVPGVIRTHPENSWGYLKPSAVTLADVFHSAGYQTAIIGK-WHLGLE 143

Query: 128 SSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQ 187
           S N  ++  +           +M  D  + R      + RN          P     DL 
Sbjct: 144 SPNTPNERGFDLFRGFL---GDMMDDYYLHRRHGVNYMRRN-----QKTVDPQGHATDLF 195

Query: 188 SLDYAIDFLKKRNGSK-PFFLAIGFHKPHIPLKFPKEYL 225
           + D+  ++LK++  S+ PFFL + ++ PH P++ P+++L
Sbjct: 196 T-DWTCEYLKQQATSESPFFLYLAYNAPHTPIQPPEDWL 233


>UniRef50_A6CBG2 Cluster: Mucin-desulfating sulfatase; n=1;
           Planctomyces maris DSM 8797|Rep: Mucin-desulfating
           sulfatase - Planctomyces maris DSM 8797
          Length = 633

 Score = 61.3 bits (142), Expect = 6e-08
 Identities = 62/219 (28%), Positives = 105/219 (47%), Gaps = 44/219 (20%)

Query: 293 IDELIGILLSYVDMQ----KTIIVLTSDHGWSLGENGLWA-KYSNFDYALKVPLIFKSPK 347
           IDE +G L   ++ Q     T+ V TSDHG+  GE+GL   +   ++  ++VPL+ + P 
Sbjct: 444 IDEGVGSLCELLESQGKLDDTVFVFTSDHGYWYGEHGLSVERRLPYEEGIRVPLLVRYPP 503

Query: 348 LIP--TVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFI--ENNS 403
           +I   TV+ E    +D+ PT++DL            H  T Q  ++G+SLVP +  E+ +
Sbjct: 504 VIKAGTVIDEFAVSVDLAPTMLDLA-----------HVKTDQK-YDGRSLVPLLKGEHPA 551

Query: 404 NGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGY-SIRTKRYRYTEWISXXXXXXXXXX 462
           +  ++F + +    +V+P+          +  MGY ++RT R++Y ++            
Sbjct: 552 DWRQSFLV-EYNSDTVFPR----------LVKMGYTAVRTPRWKYIQFNELTGMN----- 595

Query: 463 XXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVLSIRLR 501
                 ELYD + DP E +NL      K   K L   L+
Sbjct: 596 ------ELYDMLRDPYEMQNLINDPAAKETVKQLQAELK 628



 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 40/131 (30%), Positives = 63/131 (48%), Gaps = 10/131 (7%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGA 55
           +++   +I L  + V         +++ +L+DDLR      +    V  P+I+ + + GA
Sbjct: 169 LVWCCLVICLCLNAVSVKAAPAQPDMVVVLVDDLRWDELGCMGHPFVRTPHIDRISREGA 228

Query: 56  TFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYD 115
            F NAF    LC+P R  LLTGR   +  ++D      +RS       T PQ  ++ GY 
Sbjct: 229 RFRNAFCSTPLCSPVRACLLTGRYTHNHGIFDNI----NRSEHSHTLKTFPQELQKAGYA 284

Query: 116 TYSVGKVFHPG 126
           T  VGK +H G
Sbjct: 285 TAYVGK-WHMG 294


>UniRef50_Q7UKJ5 Cluster: Arylsulfatase A; n=3; Bacteria|Rep:
           Arylsulfatase A - Rhodopirellula baltica
          Length = 489

 Score = 60.9 bits (141), Expect = 8e-08
 Identities = 61/225 (27%), Positives = 93/225 (41%), Gaps = 21/225 (9%)

Query: 17  TSDVETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSR 71
           T   E P N++ I  DD     L       +  PN++ L   G  + + ++  ++C+PSR
Sbjct: 41  TDTTEKP-NVIVIFTDDQGYNDLGCYGSPNIKTPNLDRLASEGRRYTSFYSACSVCSPSR 99

Query: 72  NSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG----- 126
            +LLTG  P  + L+    + +       +  TI    K  GY T  VGK +H G     
Sbjct: 100 AALLTGCYPKRVGLHQHVLFPQSTYGLHPDEVTIADHLKSAGYATACVGK-WHLGHHKET 158

Query: 127 --KSSNFTDDYPYSWSEYPYHPPT----EMYKDAKVCRNKKTKKL-ERNLICPVSVKRQP 179
              S+ F   Y   +S    HP      +M  D +         L    L+    +   P
Sbjct: 159 LPTSNGFDSYYGIPYSNDMNHPDNKRLGKMSSDDRWTDQSSAVTLWNTPLVQDEEIIELP 218

Query: 180 -GQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKE 223
             Q     +  D AI+F+ + N  KPFFL +    PHIPL  P++
Sbjct: 219 VDQRTVTRRYTDRAIEFV-EANQDKPFFLYLPHSMPHIPLYVPED 262


>UniRef50_Q2CEI6 Cluster: Putative choline-sulfatase; n=1;
           Oceanicola granulosus HTCC2516|Rep: Putative
           choline-sulfatase - Oceanicola granulosus HTCC2516
          Length = 481

 Score = 60.9 bits (141), Expect = 8e-08
 Identities = 53/197 (26%), Positives = 96/197 (48%), Gaps = 9/197 (4%)

Query: 179 PGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKE 238
           P    PD  +   A  +L+ R   +  F+ IG   PH P   P E   +  +     P  
Sbjct: 173 PAHLHPDSFTARTARWWLETRPRPERLFMQIGLPGPHPPYD-PTEAHTRRYLDAPDLPL- 230

Query: 239 PNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAAL-YIDELI 297
           P +  D  L +   +   ++R D+   + +  + + P+   L+  +++YAA +  IDE I
Sbjct: 231 PEVD-DAELAALPAYLQEKRRHDVDVDHDSVAWKLEPSADELRRLRAHYAANVTLIDEEI 289

Query: 298 GILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSP-KLIPTV 352
           G L+  ++    +   +++  SDHG +LG++GL  K+S ++   +VPL+  SP +     
Sbjct: 290 GQLMETLETTGYLDNAVVIFCSDHGDALGDHGLSQKWSMYEPVTRVPLMVWSPGRFEARR 349

Query: 353 VHEPVELIDIFPTLVDL 369
           V    +L D+ PT++DL
Sbjct: 350 VPGLCQLFDVGPTILDL 366


>UniRef50_A0JAV5 Cluster: Sulfatase precursor; n=1; Shewanella
           woodyi ATCC 51908|Rep: Sulfatase precursor - Shewanella
           woodyi ATCC 51908
          Length = 494

 Score = 60.9 bits (141), Expect = 8e-08
 Identities = 35/128 (27%), Positives = 70/128 (54%), Gaps = 9/128 (7%)

Query: 1   MIYVVNIILLNGDRVLTSDVETPKNILFILIDDLRH----LSDKKVYLPNINFLGKTGAT 56
           ++++V      GD+V + ++    NIL+I ++D+        DK V  PNI+ L   G  
Sbjct: 10  LLFMVGCQATEGDKV-SKEIAKQPNILWIYVEDMNDWMGAYGDKTVPTPNIDQLASQGVR 68

Query: 57  FNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSN---GQGNFTTIPQFFKEHG 113
           F+      A+C+  R+++++G    +L  ++  S   D +     QG+  T+P+ F+++G
Sbjct: 69  FDKVIMPAAVCSAVRSAIISGEMQTTLGFHNHRSGRFDYNPIALPQGH-KTVPELFRDNG 127

Query: 114 YDTYSVGK 121
           Y+T+++GK
Sbjct: 128 YETFNIGK 135


>UniRef50_Q7UYS6 Cluster: Arylsulfatase A; n=3; Bacteria|Rep:
           Arylsulfatase A - Rhodopirellula baltica
          Length = 512

 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 40/134 (29%), Positives = 70/134 (52%), Gaps = 16/134 (11%)

Query: 4   VVNIILLNGDRVLTS---DVETPKNILFILIDDLRH------LSDKKVYLPNINFLGKTG 54
           ++ IILL     ++S   + +TP N+L +  DDL +       ++ K+  P+++ L ++G
Sbjct: 13  ILFIILLGSAACVSSSSAETKTPPNVLILYADDLGYGDLNLQNAESKIPTPHLDQLARSG 72

Query: 55  ATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWR--DRSNGQGNFTTIPQFFKEH 112
             F +  +   +C PSR +LLTGR        DF+        S  +    T+P+ F++H
Sbjct: 73  MRFTDGHSSSGICTPSRYALLTGRH----HWRDFHGIVNAFGESVFEPEQLTLPEMFQQH 128

Query: 113 GYDTYSVGKVFHPG 126
           GY T ++GK +H G
Sbjct: 129 GYQTAAIGK-WHLG 141


>UniRef50_Q7UHJ6 Cluster: N-acetylgalactosamine 6-sulfate sulfatase;
           n=1; Pirellula sp.|Rep: N-acetylgalactosamine 6-sulfate
           sulfatase - Rhodopirellula baltica
          Length = 500

 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 55/212 (25%), Positives = 93/212 (43%), Gaps = 25/212 (11%)

Query: 18  SDVETPKNILFILID----DLRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNS 73
           +D   P  ++F+  D    D      + +  PN++ L   G  F   ++   +C+PSR++
Sbjct: 68  ADAARPNFVVFVADDMGWGDSHTYGHELIQTPNLDRLASQGVKFTQCYSACGVCSPSRSA 127

Query: 74  LLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTD 133
           +LTGR P    +Y   S     ++ + +  T P+  KE GY+T  VGK +H      F +
Sbjct: 128 ILTGRTPYRNGVYRHLS-GNHEAHLRASEITFPELLKEVGYETCHVGK-WHLLSRQQFNN 185

Query: 134 DYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQS----- 188
                  E+P+  P E   D  +C         +N   P +  R  G+ +  L+      
Sbjct: 186 ------PEFPH--PGEHGFDHWMCTQNNASPSHQN---PDNFVRN-GEPVGQLEGYSAQL 233

Query: 189 -LDYAIDFLKK-RNGSKPFFLAIGFHKPHIPL 218
               A  +LK   + SKPF + +  H+PH P+
Sbjct: 234 VASEAARWLKDIHDPSKPFAMTVWVHEPHSPI 265


>UniRef50_A6DSG4 Cluster: Arylsulphatase A; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Arylsulphatase A - Lentisphaera
           araneosa HTCC2155
          Length = 489

 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 23/219 (10%)

Query: 15  VLTSDVETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAP 69
           V++   +   NILF L DDL +        +  Y P I+ L K G  F++ +  Q  C+P
Sbjct: 21  VVSLQAQQKPNILFYLTDDLGYGDIGCYGAEGQYTPAIDQLAKEGTKFSSFYVHQR-CSP 79

Query: 70  SRNSLLTGRRPDSLRLYDFYSYWRDRSNGQG-NFTTIPQFFKEHGYDTYSVGKVFHPGKS 128
           SR + +TG     + L       R+   G   +  T+P+  K  GY+T  VGK +H G+ 
Sbjct: 80  SRAAFMTGSYAHRVGLPQVIYKHREGPIGLNPSEITLPELMKTAGYNTALVGK-WHLGEW 138

Query: 129 SNFTDDYPYSWSEYPYHPPTEMYKDAKVCR-NKKTKKLERNLICPVSVKRQPGQSLPDLQ 187
             F   +P +   Y Y      Y   KV   ++K   +E        +++  GQ+ P + 
Sbjct: 139 KPF---HPLNHG-YDY-----FYGFLKVIEGSEKPSLIENRKELASKIQKTEGQA-PGM- 187

Query: 188 SLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLK 226
            +  AI+F+ K     PFFL      PH P  FP E  K
Sbjct: 188 -VKAAINFMTKHK-KNPFFLVYSDPMPHAPY-FPSEQFK 223


>UniRef50_A3JW99 Cluster: Putative phosphonate monoester hydrolase;
           n=1; Rhodobacterales bacterium HTCC2150|Rep: Putative
           phosphonate monoester hydrolase - Rhodobacterales
           bacterium HTCC2150
          Length = 533

 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 69/282 (24%), Positives = 121/282 (42%), Gaps = 33/282 (11%)

Query: 177 RQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRP 236
           R P +      S D A++F+++ + + P+ L + + KPH PL     Y +      V   
Sbjct: 192 RIPAEHTETAYSTDRAMEFIEQADAA-PWCLHLSYIKPHWPLVAATPYNEMYGADDV--- 247

Query: 237 KEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDEL 296
             P +       + HP     ++  +   N+    G        K+  +Y      +D+ 
Sbjct: 248 -VPVVRAQDERETVHPVYQSNQKSRVS--NVYSNQGARE-----KMIATYMGLITQVDDN 299

Query: 297 IGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPK----- 347
           +G +++++D     + T+I+ TSDHG  LG++ +  K    D +++VPLI   P      
Sbjct: 300 VGRMMAWLDETGRAKDTLIIFTSDHGDYLGDHWMGEKLYFHDQSVRVPLIVVDPSKEADA 359

Query: 348 LIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLE 407
              TV     E ID+ PT+VD   +  ++ + +          EG+SL+P I NNS    
Sbjct: 360 TRGTVDTSLTEAIDLVPTIVDF--MGGQVQENI---------LEGRSLLPLIHNNSVTWR 408

Query: 408 AFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTE 449
               SQ        +   ++P  +   +M Y  R K Y +TE
Sbjct: 409 DCVFSQADYGRSPARAILERPTSQCRMVMAYDGRWK-YIHTE 449



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 5/60 (8%)

Query: 24 KNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
          KN+LFI+ D LR+          +  PNI+ L K G  F+ ++ Q  +C PSR    TGR
Sbjct: 3  KNVLFIMCDQLRYDYLGCSGHPTIKTPNIDALAKRGVRFDQSYVQSPICGPSRACTYTGR 62


>UniRef50_Q18837 Cluster: Sulfatase domain protein protein 3,
           isoform a; n=2; Caenorhabditis elegans|Rep: Sulfatase
           domain protein protein 3, isoform a - Caenorhabditis
           elegans
          Length = 488

 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 58/237 (24%), Positives = 104/237 (43%), Gaps = 24/237 (10%)

Query: 7   IILLNGDRVLTSDVETPK---NILFILIDDLRHLS----DKKVYLPNINFLG--KTGATF 57
           ++LL+   +   D +T     N+LFI+ DDL        D  ++ PN+  L   K  A  
Sbjct: 11  LLLLHNHGITGVDGQTATQKPNVLFIMADDLGFSDVDWKDSTLHTPNLRHLAFHKNTALL 70

Query: 58  NNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTY 117
           +N++  Q LC P+R++ +TG  P  +   +      + +     F  + +  ++  Y TY
Sbjct: 71  SNSYVNQ-LCTPTRSAFMTGYYPFRVGTQNGVFLHMEPAGVPTMFPFLSENMRQLDYSTY 129

Query: 118 SVGKVFHPG--KSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSV 175
            VGK +H G  K      +  + +    Y P T  +  +    +++ K++ + L     V
Sbjct: 130 LVGK-WHLGYCKKEFLPTNRGFDYFYGFYGPQTGYFNHSADQYHRELKRVVKGLDLFEEV 188

Query: 176 KRQPGQSLPDLQS---------LDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKE 223
               G+S+PD             D A+  L   N SKPFF+ + +   H PL+  ++
Sbjct: 189 GS--GKSVPDFSQNGVYSTDLFTDVAMSVLDNHNNSKPFFMFLSYQAVHPPLQVSQQ 243


>UniRef50_UPI0000D56622 Cluster: PREDICTED: similar to CG18278-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG18278-PA - Tribolium castaneum
          Length = 475

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 77/363 (21%), Positives = 151/363 (41%), Gaps = 46/363 (12%)

Query: 25  NILFILIDDLRHLSDKKVYLPN--INFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDS 82
           N +F+L DD + L+ + +   N  +  +   G TF N +    +C PSR+++LTG+ P +
Sbjct: 18  NFVFVLTDD-QDLTLRSLDFLNQTVKLVANQGLTFTNFYVNSPICCPSRSTILTGKYPHN 76

Query: 83  LRLYDFY---SYWRDRSNGQGNFTTIPQFFKEH-GYDTYSVGKVFHP-GKSSNFTDDYPY 137
           +++++          R   Q    TI    K    Y T+  GK  +  GKS       P 
Sbjct: 77  IQVFNNSLTGGCSSVRWQQQYEKNTIASILKSRKNYTTFYAGKYLNQYGKSGKGVKHVPP 136

Query: 138 SWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLK 197
            +  +        Y +  +  N      E++ +     K              YA+DFL 
Sbjct: 137 GYDWWLGLKGNSKYYNYTLSINGSGHFFEKDYLTDKITK--------------YALDFLN 182

Query: 198 KRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMP-ISKVHRPKEPNIPKDMPLVSWHPWTDV 256
           + +    FF+ +     H P      + +  P +  +  P     P D   +   P   +
Sbjct: 183 QTDEGN-FFMMLAPPACHAPFTPADRHRRLFPDLETLKTPPFNATPSDKHWIVAMPPMSL 241

Query: 257 RKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTIIV 312
            +  +++ L+  +       K  ++  QS       +DE++  L++ +     +  T  +
Sbjct: 242 PQ--NVQILDEIY-------KNRIRTLQS-------VDEMVQALITKLQEIRVLDNTYFI 285

Query: 313 LTSDHGWSLGE-NGLWAKYSNFDYALKVPLIFKSPKLIPTVVHE-PVELIDIFPTLVDLT 370
           +TSD+G+ +G+    W K   ++  ++VP + + P +    V E  V  +DIF T++DL 
Sbjct: 286 VTSDNGFHIGQFTQPWDKRQPYESDIRVPFMIRGPNIRKKTVSEVSVSAVDIFATILDLA 345

Query: 371 KLS 373
           +++
Sbjct: 346 EIT 348


>UniRef50_Q4SG40 Cluster: Chromosome 12 SCAF14600, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 12
           SCAF14600, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 534

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 34/97 (35%), Positives = 57/97 (58%), Gaps = 5/97 (5%)

Query: 282 IRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYAL 337
           +R  YYA     D ++G L+S +     +  T++V T+DHG    E+  + K S F+ + 
Sbjct: 258 VRAFYYAMCAEADAMLGQLISALRETRLLGNTVVVFTADHGELAMEHRQFYKMSMFEGSS 317

Query: 338 KVPLIFKSPKLIPTV-VHEPVELIDIFPTLVDLTKLS 373
            VPL+F  P L+  V V++ V L+DI+PT++D+  +S
Sbjct: 318 HVPLLFTGPGLMSGVQVNQLVSLVDIYPTILDIADVS 354



 Score = 44.4 bits (100), Expect = 0.007
 Identities = 43/176 (24%), Positives = 73/176 (41%), Gaps = 24/176 (13%)

Query: 42  VYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGN 101
           V LP I +L + G TF NA+    +C PSR ++ +G      +       W +      N
Sbjct: 13  VKLPFITYLQELGVTFLNAYTNSPICCPSRAAMWSG------QFVHLTQSWNNYKCLDAN 66

Query: 102 FTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKK 161
            TT     + +GY T  +GK+ +   S + ++       E  +    E    A++  N  
Sbjct: 67  VTTWMDLLESNGYRTKRIGKLDYTSGSHSVSNRVEAWTREVQFLLRQEGRPVAQLVGNMS 126

Query: 162 TKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGS--KPFFLAIGFHKPH 215
           T ++ R                 D ++ D A  +L++R  S  +PF L +G + PH
Sbjct: 127 TVRVMRK----------------DWENTDEATRWLRQRAESPQQPFALYLGLNLPH 166


>UniRef50_Q5UEY3 Cluster: Probable sulfatase; n=1; uncultured alpha
           proteobacterium EBAC2C11|Rep: Probable sulfatase -
           uncultured alpha proteobacterium EBAC2C11
          Length = 512

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 24/205 (11%)

Query: 190 DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPL-V 248
           D +I +L  R  S PF L I F  PH P   P+      P + +H P++ ++PK +   +
Sbjct: 209 DRSIHWLSNRRESNPFCLWISFPDPHHPFDCPE------PWNLLHNPEDVDLPKFLEKDL 262

Query: 249 SWHPWTDVRKRDDIRRLN--ITFPF----GVMPTKWTLKIRQ---SYYAAALYIDELIGI 299
           +  PW   R  +    L+  +   F      MP +   ++R+   +YY     ID  +G 
Sbjct: 263 NDRPWWHRRSLESEPDLSDPVLKRFRKQGSRMPDQSEAQLREMTANYYGMISLIDHNVGR 322

Query: 300 LLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSN-FDYALKVPLIFKSPKLIP-TVV 353
           +++ +     + +TII+ TSDHG  +GE GL+ K    +D  + V +I + P +      
Sbjct: 323 VIACLREKGILDETIIIYTSDHGDHMGERGLYLKGPMLYDSLINVGMIVRGPGVAAGRSE 382

Query: 354 HEPVELIDIFPTLVDLTKLSDEIPK 378
           + P+  +D+  T  D    S  +PK
Sbjct: 383 NAPITTLDVGATFCDYAGTS--LPK 405



 Score = 34.7 bits (76), Expect = 5.8
 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 4/60 (6%)

Query: 25 NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
          N +FI  D  R        +K+  P+++ L + G  F N      +C P+R ++LTG+ P
Sbjct: 5  NFVFITSDQQRGDCYGFMGRKLKTPHLDQLRREGMHFRNCITPSPVCQPARAAILTGKLP 64


>UniRef50_A7LY81 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides ovatus ATCC 8483|Rep: Putative
           uncharacterized protein - Bacteroides ovatus ATCC 8483
          Length = 517

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 81/342 (23%), Positives = 148/342 (43%), Gaps = 37/342 (10%)

Query: 45  PNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTT 104
           P ++ L +    FN A+      +P+R S+ TGR P +  +   ++   D S  Q     
Sbjct: 52  PFVDRLAQENVWFNKAYTVMPASSPARCSMFTGRFPSATHVRTNHNI-PDISYQQ----D 106

Query: 105 IPQFFKEHGYDTYSVGK--VFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKT 162
           +    KE+GY T  VGK   +      +F  +Y + W ++    P E      + +  + 
Sbjct: 107 LVGVLKENGYKTALVGKNHAYLKPADLDFWSEYGH-WGKHKKTTPAEKETARFLNQQARG 165

Query: 163 KKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPK 222
           + LE +   P+S++ Q    +     ++ A+ ++K++    PFF+ + F +PH P +  +
Sbjct: 166 QWLEPS---PISLEEQHPTKI-----VNEALAWIKQQK-ENPFFVWVSFPEPHNPYQVCE 216

Query: 223 EYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKI 282
            Y       K+  P      KD+       +  + + +D    N+      +P     +I
Sbjct: 217 PYYSMFSPDKL--PVLKTSRKDL-AKKGEKYRILAQLEDASCPNLEQD---LP-----RI 265

Query: 283 RQSYYAAALYIDE----LIGILLSYVDMQKTIIVLTSDHGWSLGENGLWAKYSNFDYAL- 337
           R +Y      ID+    LI  L +    + T+ V+ SDHG   GE GL  K +    +L 
Sbjct: 266 RANYIGMIRLIDDQIKRLIESLKASGQYENTLFVVLSDHGDYWGEYGLIRKGAGLSESLA 325

Query: 338 KVPLIFKS--PKLIPTVVHEPVELIDIFPTLVDLTKLSDEIP 377
           ++P+++     K  P  +   V + D+FPT    + +  EIP
Sbjct: 326 RIPMVWAGYHIKNQPAPMDSHVSIADLFPTF--CSAIGAEIP 365


>UniRef50_A6DMX8 Cluster: Iduronate-sulfatase or arylsulfatase A;
           n=1; Lentisphaera araneosa HTCC2155|Rep:
           Iduronate-sulfatase or arylsulfatase A - Lentisphaera
           araneosa HTCC2155
          Length = 532

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 48/126 (38%), Positives = 63/126 (50%), Gaps = 10/126 (7%)

Query: 7   IILLNGDRVLTSDVETPKNILFILIDDLRH--LSD---KKVYLPNINFLGKTGATFNNAF 61
           + +LN  R  T+  E P NI+ I  DDL +  LS     K+  PNI+ L K G  F +  
Sbjct: 37  VSVLNEMRPKTTQSEYP-NIVLIYADDLGYGDLSSYGATKIKTPNIDRLAKNGILFTDGH 95

Query: 62  AQQALCAPSRNSLLTGRRPDSLRLYDFYS-YWRDRSNGQGNFTTIPQFFKEHGYDTYSVG 120
           +  A C PSR +LLTG  P  LR+ ++   +  DR       TTI    K  GY T  VG
Sbjct: 96  STSATCTPSRYALLTGEYP--LRINNYSPVFCADRLIIDTKKTTIASLLKRKGYTTACVG 153

Query: 121 KVFHPG 126
           K +H G
Sbjct: 154 K-WHLG 158


>UniRef50_A6C1V3 Cluster: Putative secreted sulfatase ydeN; n=1;
           Planctomyces maris DSM 8797|Rep: Putative secreted
           sulfatase ydeN - Planctomyces maris DSM 8797
          Length = 470

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 61/239 (25%), Positives = 104/239 (43%), Gaps = 31/239 (12%)

Query: 21  ETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNSL 74
           E P N++F L+DDL   +D   Y       PNI+ L   G  F   ++    C+P+R +L
Sbjct: 31  EKPWNVVFFLVDDLGW-TDLGCYGSDFYQSPNIDQLAAEGMKFTQNYSACNACSPTRGAL 89

Query: 75  LTGRRPDSLRLYDFYSYWRD------------RSNGQGNFTTIPQFFKEHGYDTYSVGKV 122
           LTG  P    L D+   W              + +    +TT+P+  +  GY T+ VGK 
Sbjct: 90  LTGMYPARTHLTDWIPGWAKSYTDFPLKPPEWKKHLDQKYTTLPEALRTAGYQTFHVGK- 148

Query: 123 FHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQS 182
           +H G   N   D+ +  +    +    + +           K + +L      +RQ  + 
Sbjct: 149 WHLGGRGNLPQDHGFDVNISGTN--RGLPRSYHFPYGGDAMKWDSSL---TEAERQ-DRY 202

Query: 183 LPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQ---MPISKVHRPKE 238
           L D +  D A+  ++++   KPFFL   F+  H P++   + +K+   +P  K H+  E
Sbjct: 203 LTD-RMADEAVALIRQQQ-DKPFFLYCSFYSVHSPIQGRPDLVKKYKGLPAGKRHKNPE 259


>UniRef50_Q7UYD2 Cluster: Sulfatase 1; n=2; Bacteria|Rep: Sulfatase
           1 - Rhodopirellula baltica
          Length = 478

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 61/218 (27%), Positives = 95/218 (43%), Gaps = 24/218 (11%)

Query: 18  SDVETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRN 72
           +D E P NI+ IL DDL         D  +  P+++ L   G  F  A++   +C+PSR 
Sbjct: 55  ADAEPP-NIVLILADDLGFNQIGAYGDTPIQTPHLDQLAANGIRFTQAYSGNTVCSPSRV 113

Query: 73  SLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFT 132
           SL TGR  D  RL D  S   +    +    TI    K  GYDT   GK +  G     T
Sbjct: 114 SLFTGR--DG-RLMDNNS---NTVQLKDIDVTIAHVLKHAGYDTALFGK-YSIGSQMGVT 166

Query: 133 DDYPYSWSE-YPYHPPTEMYKD--AKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSL 189
           D     +   Y  +   E ++     + R+ K  ++E N       K    Q+L   +++
Sbjct: 167 DPLAMGFDTWYGMYSILEGHRQYPTILWRDGKKLRIEEN---EAGRKGAYAQALFTHEAI 223

Query: 190 DYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQ 227
            Y      K++   PFF+ + +  PH  L  P E++++
Sbjct: 224 QYI-----KQDHDNPFFVLLAYSSPHAELAAPPEFVER 256


>UniRef50_Q7UL93 Cluster: N-acetylgalactosamine 6-sulfatase; n=1;
           Pirellula sp.|Rep: N-acetylgalactosamine 6-sulfatase -
           Rhodopirellula baltica
          Length = 470

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 64/232 (27%), Positives = 100/232 (43%), Gaps = 37/232 (15%)

Query: 15  VLTSDVETPKNILFILIDDLR----HLSDKKVY-LPNINFLGKTGATFNNAFAQQALCAP 69
           +++++     +ILFI+ DD+     H     V   PNI+ L + G  F+NA+A   +C P
Sbjct: 38  LVSAEAAEQPHILFIMADDMGWKDLHCQGNDVLRTPNIDALAEAGVRFDNAYAGSTVCTP 97

Query: 70  SRNSLLTGRRPDSLRL----YDFYSYWRD-------RSNGQ--GNFTTIPQFFKEHGYDT 116
           +R SL+TG  P  L +     D  S+W D        +N +     TT+ +  K  GY T
Sbjct: 98  TRASLMTGLAPARLHITQHGADSKSFWPDDRLIQPPPTNHELPHETTTMAERLKAAGYTT 157

Query: 117 YSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKV--CRNKKTKKLERNLICPVS 174
              GK +H G    +       W       PTE   D  V  C              P  
Sbjct: 158 GFFGK-WHLGGDKKY-------W-------PTEHGFDVNVGGCGLGGPPTYFDPYRIPAL 202

Query: 175 VKRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLK 226
             R+ G+ L D +  D  I F+ +R   KP F+ +  + PH P + P++ ++
Sbjct: 203 PPRKEGEYLTD-RLADETIAFM-RREKDKPMFVCLWTYNPHYPFEAPEDLIE 252


>UniRef50_A6DR15 Cluster: Arylsulfatase; n=2; Lentisphaera araneosa
           HTCC2155|Rep: Arylsulfatase - Lentisphaera araneosa
           HTCC2155
          Length = 526

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 68/233 (29%), Positives = 99/233 (42%), Gaps = 39/233 (16%)

Query: 16  LTSDVETPKNILFILIDDLRHLSDKKVY-----LPNINFLGKTGATFNNAFAQQALCAPS 70
           ++ DV +  NI+ IL DD+ + SD   Y      PNI+ L + G  F   F   A C PS
Sbjct: 34  MSYDVASRPNIIVILADDMGY-SDLGCYGGEIQTPNIDALAREGVRFTG-FKNTARCTPS 91

Query: 71  RNSLLTGRRPDSL---RLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH--- 124
           R SLLTGR   S+    +         R     +  TI +  K HGY T  VGK +H   
Sbjct: 92  RASLLTGRYSHSVGVGAMQQDQHLPGYRGQLSADAPTIAEILKPHGYATGVVGK-WHQAV 150

Query: 125 PGKSS---------NFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSV 175
            GKS           F   Y   W    Y  P  M K+++   +  T   +  L   +S 
Sbjct: 151 TGKSKQKPLFPLDRGFDFFYGTWWGAKDYFSPKFMMKNSEHIPDSTTYPADFYLTHALS- 209

Query: 176 KRQPGQSLPDLQSLDYAIDFLKKRNGSK-PFFLAIGFHKPHIPLKFPKEYLKQ 227
                         D AI+F+  + G + PFFL +  + PH P++ P + +++
Sbjct: 210 --------------DSAIEFVDAQVGQQNPFFLYLAHYAPHAPIQAPADRIQK 248


>UniRef50_A6DKS7 Cluster: N-acetylglucosamine-6-sulfatase; n=1;
           Lentisphaera araneosa HTCC2155|Rep:
           N-acetylglucosamine-6-sulfatase - Lentisphaera araneosa
           HTCC2155
          Length = 515

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 78/322 (24%), Positives = 129/322 (40%), Gaps = 32/322 (9%)

Query: 45  PNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTT 104
           PNI+ +   G  F+      A+C PSR ++LTG+      L  FY   ++     G   T
Sbjct: 48  PNIDRIASEGIRFDRCLVTNAICGPSRATILTGKYS---HLNGFY---KNDMYFDGRQIT 101

Query: 105 IPQFFKEHGYDTYSVGKVFH----PGKSSNFTDDYPYSWSEYPYHP-------PTEM--Y 151
            P+  ++ GY T  +GK +H    P    +F     Y      YHP       PT+   Y
Sbjct: 102 FPKLLRQAGYQTAVIGK-WHLASLPTGFDHFEVITGYGGQGKYYHPVMNRNGEPTKHRGY 160

Query: 152 KDAKVCR-NKKTKKLERNLICPVSVKRQ-PGQSLPDLQSLDYAIDFLKKRNGSKPFFLAI 209
               + + N +  K +R+   P  +  Q        L S  Y   F K +   KP  L  
Sbjct: 161 TTEVITKLNMEWLKNQRDPNKPFMLMMQHKAPHRAWLPSPKYMNAF-KDKKFPKPANLHT 219

Query: 210 GFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITF 269
            +      +K     +K        +   P       L +WH   D  +     +  ++ 
Sbjct: 220 DYQGKASHVKKQDMMIKDSMNPGDLKLTPPKYLDGADLANWHKAYD-EENAAFAKAKLS- 277

Query: 270 PFGVMPTKWTL-KIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGEN 324
             G     W   +  + Y      ID+ IG +L+Y+D     + T+++ +SD G+ LGE+
Sbjct: 278 --GKALRSWNYQRYIRDYVRCVQSIDDSIGEVLNYLDESGLAENTLLIYSSDQGFFLGEH 335

Query: 325 GLWAKYSNFDYALKVPLIFKSP 346
           G + K   ++ AL+ PL+ + P
Sbjct: 336 GWFDKRFMYEEALRTPLVMRWP 357


>UniRef50_A6C430 Cluster: Arylsulphatase A; n=1; Planctomyces maris
           DSM 8797|Rep: Arylsulphatase A - Planctomyces maris DSM
           8797
          Length = 503

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 61/236 (25%), Positives = 103/236 (43%), Gaps = 20/236 (8%)

Query: 1   MIYVVNIILLNGDRVL--TSDVETPK--NILFILIDDLRH-----LSDKKVYLPNINFLG 51
           +I V++I+  N       T+ V++P   NI+ +L DDL +          +  PNI+   
Sbjct: 8   LIIVISILFTNESLAAEPTASVKSPARPNIMVVLCDDLGYGDLACYGHPVIQSPNIDRFA 67

Query: 52  KTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKE 111
           K G    + +A    C+PSR  L+TGR P  + +Y++        + +    TI    ++
Sbjct: 68  KEGLKLTSCYAAHPNCSPSRAGLMTGRTPFRVGIYNWIP-MLSPMHVRKREITIATLLRQ 126

Query: 112 HGYDTYSVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLIC 171
            GY T  VGK +H     N       S   + +   T+   +  +  ++      RN   
Sbjct: 127 AGYATCHVGK-WHLNGMFNMVGQPQPSDHGFDHWFSTQ---NNALPTHENPFNFVRN-AR 181

Query: 172 PVSVKRQPGQSLPDLQSLDYAIDFLKK-RNGSKPFFLAIGFHKPHIPLKFPKEYLK 226
           PV     P Q        D A ++L + R+  KPFF+ + FH+PH P+   + + K
Sbjct: 182 PVG----PLQGFASQLVADEAEEWLTQLRDKEKPFFMFVCFHEPHEPIASAERFRK 233


>UniRef50_A6BZT7 Cluster: Putative arylsulfatase; n=1; Planctomyces
           maris DSM 8797|Rep: Putative arylsulfatase -
           Planctomyces maris DSM 8797
          Length = 459

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 68/246 (27%), Positives = 108/246 (43%), Gaps = 36/246 (14%)

Query: 9   LLNGDRVLTSDVETPKNILFILIDDLRHLS-----DKKVYLPNINFLGKTGATFNNAFAQ 63
           LL   R+  ++ + P NI+FI+ DDL +        KK+  P+I+ L   G  F  A+A 
Sbjct: 3   LLASVRLEATEKQKP-NIIFIMADDLGYAELGCYGQKKIKTPHIDKLAAEGMKFTQAYAG 61

Query: 64  QALCAPSRNSLLTGRRP--DSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK 121
             +C PSR+ L+TG+     ++R  D      +        TT+ +  K  GY T + GK
Sbjct: 62  SMVCQPSRSVLMTGQHTGHTAVRANDLNQLLYEED------TTVAEVLKIAGYATGAFGK 115

Query: 122 -----VFHPGK-SSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSV 175
                   PG+      DD+     +   H     Y    +  N      E  L+ P + 
Sbjct: 116 WGLGYEGTPGRPGQQGFDDFTGQLLQVHAH----FYYPFWIWNN------EHRLMLPENE 165

Query: 176 KRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKE----YLKQMPIS 231
             Q G+ + DL   D A  F++K N ++PFF  + +  PH+ L  P+E    Y  Q P  
Sbjct: 166 NNQRGRYIHDLIHED-AKAFIQK-NKAQPFFAYLPYIIPHVELVVPEESEKPYRGQFPKK 223

Query: 232 KVHRPK 237
           ++  P+
Sbjct: 224 QILDPR 229


>UniRef50_A3HYT7 Cluster: Arylsulphatase A; n=1; Algoriphagus sp.
           PR1|Rep: Arylsulphatase A - Algoriphagus sp. PR1
          Length = 437

 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 68/223 (30%), Positives = 96/223 (43%), Gaps = 24/223 (10%)

Query: 21  ETPKNILFILIDDLR-----HLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLL 75
           + P NI+ I+ DDL               P I+ +   GA F NAFA Q LC PSR  ++
Sbjct: 28  DRPPNIILIMADDLGVETIGSYGGTSYQTPFIDAMAAQGAKFENAFA-QPLCTPSRVQIM 86

Query: 76  TGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY 135
           TG+   ++R Y  +    DRS      TT  +  K+ GY T   GK +  GK S+    +
Sbjct: 87  TGQY--NVRNYTVFGQ-LDRSQ-----TTFAKLLKDAGYKTAIAGK-WQLGKESDSPQHF 137

Query: 136 PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDF 195
            +  S    H      K+    R      LE N    V      GQ   D+ S D+ IDF
Sbjct: 138 GFEESCLWQHMLGATDKNGNDTR-YSNPVLEIN---GVPKHFDGGQFSTDITS-DFLIDF 192

Query: 196 LKKRNGSKPFFL---AIGFHKPHIPLKFPKEYLKQMPISKVHR 235
           ++K N  +PFF     I  H P +P    K++    P S  ++
Sbjct: 193 MEK-NKDQPFFAYYPMIITHCPFVPTPDSKDWDPSSPGSPTYK 234


>UniRef50_UPI0000D55F5E Cluster: PREDICTED: similar to CG8646-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG8646-PA - Tribolium castaneum
          Length = 626

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 9/146 (6%)

Query: 15  VLTSDVETPK-NILFILIDDLRHLS-----DKKVYLPNINFLGKTGATFNNAFAQQALCA 68
           V+ S  +T K NI+ I+ DD+           ++  PNI+ L   G   N+ + Q ALC 
Sbjct: 13  VVASFAQTKKPNIIVIVADDMGFNDVGFHGSNEIPTPNIDALAYNGVILNSHYTQ-ALCT 71

Query: 69  PSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPG-K 127
           PSR++ LTG+ P  L +        +      N T +PQ+ K +GY T+++GK +H G  
Sbjct: 72  PSRSAFLTGKYPIHLGMQHLVILEPEPWGLPLNETILPQYLKRNGYATHAIGK-WHLGFF 130

Query: 128 SSNFTDDYPYSWSEYPYHPPTEMYKD 153
              +T  Y    S Y Y     M  D
Sbjct: 131 RKEYTPTYRGFDSHYGYDMRRNMTVD 156


>UniRef50_Q3IBP8 Cluster: Sulfatase; n=1; uncultured
           sulfate-reducing bacterium|Rep: Sulfatase - uncultured
           sulfate-reducing bacterium
          Length = 472

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 33/94 (35%), Positives = 56/94 (59%), Gaps = 6/94 (6%)

Query: 282 IRQSYYAAALYIDELIGILLSYV--DMQKTIIVLTSDHGWSLGENGLWAKYSNFDY--AL 337
           I + Y A   Y D +IG +++ +  +  +T+++LTSDHG SLGE+G + ++    Y   +
Sbjct: 175 ISKLYDAEIRYTDAMIGHVMASIAANRAETLLILTSDHGESLGEHGYFYQHGALAYQPCM 234

Query: 338 KVPLIFKSPKLIP--TVVHEPVELIDIFPTLVDL 369
            +P+IF  P  IP  T +  PV  ID+ PT++ +
Sbjct: 235 HIPMIFSQPGRIPEGTRIDLPVSNIDLVPTILSV 268


>UniRef50_A6FX65 Cluster: Probable arylsulfatase ; probable
           choline-sulfatase; n=1; Plesiocystis pacifica SIR-1|Rep:
           Probable arylsulfatase ; probable choline-sulfatase -
           Plesiocystis pacifica SIR-1
          Length = 753

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 36/114 (31%), Positives = 61/114 (53%), Gaps = 5/114 (4%)

Query: 282 IRQSYYAAALYIDELIGILLSYVDMQ--KTIIVLTSDHGWSLGENGLWAK-YSNFDYALK 338
           +R +Y    L++D  +  LL+++D +    +++LTSDHG   GE G +   +S  D  L+
Sbjct: 554 VRDAYDNELLWVDLHLSRLLAFIDARYPDALVILTSDHGEEFGERGNYGHGFSLADSELR 613

Query: 339 VPLIFKSPKLIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEG 392
           VPL    P + P V   PV L+ + PT+++L  L   +P  ++     +L  EG
Sbjct: 614 VPLAIAGPGVPPGVEARPVSLVGVAPTVLEL--LGVPVPAGMSPSRLLELPAEG 665


>UniRef50_A6DNJ0 Cluster: Sulfatase; n=1; Lentisphaera araneosa
           HTCC2155|Rep: Sulfatase - Lentisphaera araneosa HTCC2155
          Length = 630

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 58/216 (26%), Positives = 97/216 (44%), Gaps = 23/216 (10%)

Query: 23  PKNILFILIDDLRHLSDKKVYLPN---------------INFLGKTGATFNNAFAQQALC 67
           P NI+F+L DDL +  D   Y PN               ++ + K G  + +  +   +C
Sbjct: 24  PPNIIFMLADDLGY-GDLSSYNPNAEGEAPNNTPIRTPTLDSMAKNGVRYTDFHSAAPIC 82

Query: 68  APSRNSLLTGRRPDSLRLYDFYSYWRDRSNG--QGNFTTIPQFFKEHGYDTYSVGKVFHP 125
           +P+R +LLT R P   RL ++   +R   +G    N  TI  + KE GY T + GK ++ 
Sbjct: 83  SPARRALLTARYPS--RLGEWAEAYRGSPDGVVAKNDPTIAMWLKEAGYATAAYGK-WNI 139

Query: 126 GKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPD 185
           G+S + +    + + ++        Y   K        +          V    GQ L D
Sbjct: 140 GESKDVSWPGAHGFDDWLIIDHNTGYFQHKNANKDCEGRPMLFETGGERVTNLEGQYLTD 199

Query: 186 LQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFP 221
           + + D AIDF+++    +PFF+ + +  PH PL+ P
Sbjct: 200 IWT-DKAIDFIQETK-DQPFFIYLPWSIPHTPLQDP 233


>UniRef50_A6DJ11 Cluster: Arylsulfatase A; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Arylsulfatase A - Lentisphaera
           araneosa HTCC2155
          Length = 462

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 68/250 (27%), Positives = 103/250 (41%), Gaps = 35/250 (14%)

Query: 7   IILLNGDRVLTSDVETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAF 61
           + L++   ++ +D   P N++ IL DD     L     K +  P I+ L + G    + +
Sbjct: 7   LTLISLQFLMAADTSKP-NVIIILTDDQGYNDLSCYGSKTIKSPRIDQLAEEGLKLTSYY 65

Query: 62  AQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK 121
               +C+ SR +LLTGR P  + +   +   R          TI +  K  GY T +VGK
Sbjct: 66  VASPVCSASRAALLTGRYPKLVGVPGVFFPNRGHKGLDPKHQTIAKLLKSVGYATKAVGK 125

Query: 122 VFHPGKSSNFT------DDY---PYSWSEYP----YHPPTEMYKDAKVCRNKKTKKLERN 168
            +H G    F       D Y   PYS    P     +    +Y++  V +    K  E N
Sbjct: 126 -WHLGDELEFLPTNQGFDSYYGIPYSNDMTPAFSMKYSENCLYREG-VDQEALKKAFEAN 183

Query: 169 LICPVSVK------------RQPG-QSLPDLQSLDYAIDFLKKRNGS-KPFFLAIGFHKP 214
            I PV +K              P  QS    +  D +I F+ +   S KPFFL +    P
Sbjct: 184 KIKPVGMKDKVPLMRNDECIEMPADQSTITKRFTDESIKFIDESTASNKPFFLYLAHSMP 243

Query: 215 HIPLKFPKEY 224
           H PL   K++
Sbjct: 244 HTPLYVSKDF 253



 Score = 37.5 bits (83), Expect = 0.83
 Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 14/110 (12%)

Query: 293 IDELIGILLSYVD----MQKTIIVLTSDHG-W----SLGENGL---WAKYSNFDYALKVP 340
           ID  +G ++ +++     + T+ + TSD+G W    S G + L     K ++F+   +VP
Sbjct: 269 IDYNVGRIIDHLNEKNIAENTLFIYTSDNGPWLIKKSHGGSALPLFEGKMTSFEGGQRVP 328

Query: 341 LIFKSPKLIP--TVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQL 388
            I + P  IP  +V +E    +DIFPTL  +T    +    +N K+  +L
Sbjct: 329 AIIRWPAKIPKDSVSNEMTLSMDIFPTLAKITGAKAQDADLINGKNALEL 378


>UniRef50_A3I0L2 Cluster: Arylsulfatase A; n=2; Bacteroidetes|Rep:
           Arylsulfatase A - Algoriphagus sp. PR1
          Length = 481

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 57/216 (26%), Positives = 93/216 (43%), Gaps = 30/216 (13%)

Query: 18  SDVETPKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSR 71
           +++ +  NI+ I  DD+ +  D  VY       PN++ +   G  F   +   A+C+ SR
Sbjct: 32  TEIPSKPNIVLIFADDMGY-GDLGVYGATQWETPNLDKMASDGVRFTQFYVPHAVCSASR 90

Query: 72  NSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNF 131
            +LLTG   + L ++    +   +       TTI +  K +GY T  VGK +H G  + F
Sbjct: 91  AALLTGTYANRLEIFGALDH-SAKHGLNPEETTIAEMLKANGYATGIVGK-WHLGHQAPF 148

Query: 132 T------DDY---PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQS 182
                  D Y   PYS   +P+HP  + Y             L  N      +     QS
Sbjct: 149 LPTEQGFDSYYGLPYSNDMWPHHPEVKGY--------YPPLPLYEN---TAVIDTLDDQS 197

Query: 183 LPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPL 218
           +      + A++F+ + +  KPFFL +     H+PL
Sbjct: 198 MLTTNYTEKALEFI-ENSKDKPFFLYLAHSMTHVPL 232


>UniRef50_A7SRP2 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 491

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 60/217 (27%), Positives = 92/217 (42%), Gaps = 22/217 (10%)

Query: 25  NILFILIDDLRH----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRP 80
           ++LF+L DDL          K+  PNI+ L   G   +N + Q  +C P+R SL+TG+ P
Sbjct: 26  HLLFVLADDLGWSDVGFHGSKIQTPNIDRLAANGVILDNYYVQP-VCTPTRASLMTGKYP 84

Query: 81  DSLRLYDFYSYWRDRSNGQG-NFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSW 139
               L     +   R  G   N T +PQ  ++ GY T+ +GK +H G          Y+W
Sbjct: 85  IHTGLQHGIIH-NGRPYGLPLNLTLLPQKLRKAGYSTHMLGK-WHLGF---------YNW 133

Query: 140 SEYP-YHPPTEMYKDAKVCRNKKTKKLERNLICPVS---VKRQPGQSLPDLQSLDYAIDF 195
              P Y      Y       N  T   +  L    +   V+ Q G     L +   A   
Sbjct: 134 ESTPTYRGFDTFYGFYSGAENHYTHVQDHYLDLRDNEEIVRDQNGTYSAHLFT-KRAEQI 192

Query: 196 LKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISK 232
           ++  + S P F+ + F   H P++ PKEY+ +    K
Sbjct: 193 VRAHDPSTPLFMYMAFQNVHSPVQAPKEYIDRYSFIK 229


>UniRef50_Q5V6E4 Cluster: Sulfatase; n=1; Haloarcula
           marismortui|Rep: Sulfatase - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 471

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 79/366 (21%), Positives = 143/366 (39%), Gaps = 42/366 (11%)

Query: 18  SDVETPKNILFILIDDLRHL-----SDKKVYLPNINFLGKT--GATFNNAFAQQALCAPS 70
           S+   P NI++I +D +R+         +   PN+  +     G +F++  A      PS
Sbjct: 2   SESTAPSNIIWITLDSIRYDRTTLDGHARATTPNMERIANQAGGVSFSSCIAAANWSLPS 61

Query: 71  RNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSN 130
             S+ TG  P+  R      Y  ++     N  T+ +  +E GY T  V    +  +S+ 
Sbjct: 62  AASIHTGTFPEHHRT----GYGTNKLPQSVN--TVAERLQEVGYQTVGVSANHYFSESTG 115

Query: 131 FTDDYPYSWSEYPYHPPTEMYKDAK---VCRNKKTKKLERNLICPVSVKRQPGQSLPDLQ 187
            +  +      + +  PT+++++     + R     +     +     K +P   + ++ 
Sbjct: 116 LSRGF----ETFKHINPTDLFREVSPRTLLRFLSNLRSHSGGLSTEKTKHRPDFFVNEVV 171

Query: 188 SLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPL 247
               +     +    +PFFL+  +H  H+P   P  +  +     V  P+  +       
Sbjct: 172 KKQVS----SRTEREEPFFLSAHYHGAHLPYYPPPAWQDRFSSDLVESPRAASERAFKHT 227

Query: 248 VSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV--- 304
              H           R +     FG     W   +   Y     Y D LIG L  ++   
Sbjct: 228 ADLH-----------RGIANVSEFG--EADWNA-LNVMYDTLVAYSDSLIGELFDHLKAL 273

Query: 305 DMQKTIIVLTSDHGWSLGENGLWA-KYSNFDYALKVPLIFKSPKLIPTVVHEPVELIDIF 363
           D++ T+ V+T+DHG  LGE GL   K+   D  + VP +      +     E V+ IDI 
Sbjct: 274 DLENTVFVVTADHGDLLGECGLLGHKFVLHDGLIHVPAVVHGLDSVADKQDELVQHIDIV 333

Query: 364 PTLVDL 369
            TLV++
Sbjct: 334 RTLVEI 339


>UniRef50_A5ZER6 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides caccae ATCC 43185|Rep: Putative
           uncharacterized protein - Bacteroides caccae ATCC 43185
          Length = 463

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 66/228 (28%), Positives = 108/228 (47%), Gaps = 24/228 (10%)

Query: 8   ILLNGDRVLTSDVE--TPKN--ILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFN 58
           +L++GD    S VE  T KN  IL ILIDD  +     +  K++  PNI+ L   G  F 
Sbjct: 12  LLVSGDIQTVSAVESKTDKNPNILVILIDDAGYNDFGFMGSKEMQTPNIDALTSEGVVFT 71

Query: 59  NAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQG-NFTTIPQFFKEHGYDTY 117
           +A     + +PSR  L+TGR       + +     DR+NG      TI + FK +GY T 
Sbjct: 72  DAHVAATVSSPSRACLITGRYG---HRFGYECNLSDRTNGLPLEEETIAEVFKTNGYRTA 128

Query: 118 SVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKK-LERNLIC-PVSV 175
           ++GK +H G      + +P +     ++      +D      K  +   ERNL+     V
Sbjct: 129 AIGK-WHLGSRD---EQHPNNRGFDLFYGMKAGGRDYFYNEKKSDRPGDERNLLLNDRQV 184

Query: 176 KRQPGQSLPDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPLKFPKE 223
           K +  + L D  S + A++F+ +   S+PF + + ++  H P++   E
Sbjct: 185 KFE--KYLTDAFS-EKAVEFINE--SSQPFMMYLAYNAVHTPMQATDE 227


>UniRef50_A3HWF8 Cluster: Mucin-desulfating sulfatase; n=4;
           Bacteroidetes|Rep: Mucin-desulfating sulfatase -
           Algoriphagus sp. PR1
          Length = 558

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 12/156 (7%)

Query: 3   YVVNIILLNGDRVLTSDVETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATF 57
           + + I LL G +    +     NI+FI+ DD     +    +  +  PNI+ +   G  F
Sbjct: 10  FFLGITLLTGCQEAKEEKSQRPNIIFIMSDDHAYQAISAYDNSLIETPNIDRIADMGILF 69

Query: 58  NNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTY 117
            NA    ++CAPSR ++LTG+        D Y Y  D +N      T PQ  ++ GY T 
Sbjct: 70  TNASVTNSICAPSRATILTGKHSHLNGKIDNY-YPFDTTN-----VTFPQLLQDGGYQTA 123

Query: 118 SVGKVFHPGKSSNFTDDYPYSWSEYPYHPPTEMYKD 153
             GK+ H G +    D +     +  Y+ P  + K+
Sbjct: 124 MFGKL-HFGNNPKGFDQFKILPGQGSYYNPDFITKN 158



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 29/75 (38%), Positives = 41/75 (54%), Gaps = 5/75 (6%)

Query: 277 KWTL-KIRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYS 331
           KW   +  Q Y      +DE +G LL Y++    ++ TIIV TSD G+ LGE+G + K  
Sbjct: 314 KWKFQRYMQDYLGTIKSVDENVGRLLDYLEENNLLENTIIVYTSDQGFYLGEHGWFDKRF 373

Query: 332 NFDYALKVPLIFKSP 346
            +D + K PLI   P
Sbjct: 374 VYDESFKTPLIVAWP 388


>UniRef50_A1R7Q8 Cluster: Putative sulfatase family protein; n=1;
           Arthrobacter aurescens TC1|Rep: Putative sulfatase
           family protein - Arthrobacter aurescens (strain TC1)
          Length = 536

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 55/200 (27%), Positives = 84/200 (42%), Gaps = 16/200 (8%)

Query: 179 PGQSLPDLQSLDYAIDFLKKRNGS-KPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPK 237
           P    P     + AI+ LK   G  +PFF+ + F  PH P   P  Y      S ++ PK
Sbjct: 227 PADVHPTSYVSEKAIEHLKDAAGQDQPFFMFVSFPDPHHPFSPPAGY------SDLYNPK 280

Query: 238 EPNIPKDMPLVSWHPWTDVRKRDDIR---RLNITFPFGVMPTKWTLKIRQSYYAAALYID 294
           +  +P             VR   + R    ++ T  +     ++       Y    + +D
Sbjct: 281 DLPLPLGFEQDHSGSPEHVRNMMEHRGEPNMDPTMTWAATEEQYRFAAAAQYGLITM-MD 339

Query: 295 ELIGILLSYVDMQ----KTIIVLTSDHGWSLGENGLWAK-YSNFDYALKVPLIFKSPKLI 349
           E IG +L  +D Q     TI+V TSDHG   G++GL  K + ++     VPL+   P   
Sbjct: 340 EHIGRILDELDRQGLADDTIVVFTSDHGDLFGDHGLMLKHFVHYRAVTNVPLVVHLPGTP 399

Query: 350 PTVVHEPVELIDIFPTLVDL 369
           P      V   D+ PTL++L
Sbjct: 400 PRRAKALVSSADLAPTLLEL 419



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 39/115 (33%), Positives = 48/115 (41%), Gaps = 17/115 (14%)

Query: 25  NILFILIDDLR--HLS---DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N+LFI+ D LR  HL    +  V  PN++ L      F NA      C P+R SL+TGR 
Sbjct: 14  NVLFIIADQLRADHLGFAGNATVKTPNLDALAAKSVVFENATVANPTCMPNRASLMTGRW 73

Query: 80  PDSLRLYDFYSYWRDRSNG---QGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNF 131
           P         S    R NG        T+P      GY T  VGK+ H      F
Sbjct: 74  P---------SAHGTRCNGITLDPLTRTVPGSLGAGGYRTVGVGKLHHQNMGWEF 119


>UniRef50_Q9HSV3 Cluster: Putative uncharacterized protein; n=1;
           Halobacterium salinarum|Rep: Putative uncharacterized
           protein - Halobacterium salinarium (Halobacterium
           halobium)
          Length = 451

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 5/116 (4%)

Query: 257 RKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYV---DMQKTIIVL 313
           R+   + R     P  +   +W L+ +Q Y A   Y+D+ IG LL      + + T++V 
Sbjct: 211 RRSQKLARKATHHPDELSDDEWELQ-QQLYKAECSYLDDQIGRLLDSFPEPERENTLLVF 269

Query: 314 TSDHGWSLGENGLWAKYSNF-DYALKVPLIFKSPKLIPTVVHEPVELIDIFPTLVD 368
           T+DHG   GE+GL      F +  + VP    +P    T V+E   LIDI PT++D
Sbjct: 270 TADHGEMHGEHGLGGHPQQFWEEVIHVPCAISAPGFEATTVNEQAALIDIPPTILD 325


>UniRef50_Q5V6E3 Cluster: Putative sulfatase; n=1; Haloarcula
           marismortui|Rep: Putative sulfatase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 493

 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 45/176 (25%), Positives = 85/176 (48%), Gaps = 19/176 (10%)

Query: 198 KRNGSK--PFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTD 255
           ++NG++  PFF  + + +PH+P + P  +L +     +    +P+   D+   +  PW  
Sbjct: 193 EQNGTEDDPFFYFLNYVEPHLPYEPPAPFLDEY----LPDGADPSRVSDL---NQDPWQY 245

Query: 256 VRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVDMQKTIIVLTS 315
           V    ++   ++    G+   +      Q        ++ L   L     + +T I+L  
Sbjct: 246 VAGDQELTDADVEIFKGLYEAELAYLDTQ--------LERLYDTLAEQCILDETAIILVG 297

Query: 316 DHGWSLGENGLW-AKYSNFDYALKVPLIFKSPKLI-PTVVHEPVELIDIFPTLVDL 369
           DHG ++GE+GL   +Y  ++  + VPL+ + P+L     V  PVEL D++PT+ DL
Sbjct: 298 DHGENIGEHGLMDHQYCLYETLIHVPLVIRYPELFDEEEVSGPVELRDLYPTVTDL 353


>UniRef50_Q8A2F6 Cluster: Putative sulfatase yidJ; n=4;
           Bacteroidales|Rep: Putative sulfatase yidJ - Bacteroides
           thetaiotaomicron
          Length = 508

 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 85/368 (23%), Positives = 150/368 (40%), Gaps = 42/368 (11%)

Query: 42  VYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQGN 101
           V+ PNI+   +      +A +   L +P R  LLTG  P+   +    +  R  S+ + +
Sbjct: 59  VHTPNIDTFARESMVLTSAQSNCPLSSPHRGMLLTGMYPNRSGVPLNCNSTRPISSLRDD 118

Query: 102 FTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDY-PYSWSEYPY---HPPTEMYKDAKVC 157
              I   F + GYD    GK+     + N  ++   Y  ++ P    + P E        
Sbjct: 119 AECIGDVFSKAGYDCAYFGKLHADFPTPNDPENPGQYVETQRPVWDAYTPKEQRHGFNYW 178

Query: 158 RNKKTKKLERNL-ICPVSVKRQPGQSLPDLQSLDYAIDFLKK----RNGSKPFFLAIGFH 212
            +  T    +N        KR   +    L      + +LK     R+  KPFF+ +G +
Sbjct: 179 YSYGTFDEHKNPHYWDTDGKRHDPKEWSPLHESGKVVSYLKNEGNVRDTKKPFFIMVGMN 238

Query: 213 KPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTDVRKRDDIRRLNITFPFG 272
            PH P +   +  +Q          + N+ KD PL S      +R   D   LN+     
Sbjct: 239 PPHSPYRSLNDCEEQ----------DFNLYKDQPLDSLL----IRPNVD---LNM----- 276

Query: 273 VMPTKWTLKIRQSYYAAALYIDELIGILLSYVDM----QKTIIVLTSDHGWSL-GENGLW 327
               K    +R  Y+A+   +D   G +L  +      + T+++  SDHG ++  +    
Sbjct: 277 ----KKAESVRY-YFASVTGVDRAFGQILEALKQLGLDKNTVVIFASDHGETMCSQRTDD 331

Query: 328 AKYSNFDYALKVPLIFKSP-KLIPTVVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTS 386
            K S +  ++ +P + + P K+ P V    +   DI PT++ L  L D IP  +  ++ +
Sbjct: 332 PKNSPYSESMNIPFLVRFPGKIQPRVDDLLLSAPDIMPTVLGLCGLGDSIPSEVQGRNFA 391

Query: 387 QLCFEGKS 394
            L F+ K+
Sbjct: 392 PLFFDEKA 399


>UniRef50_Q89YS5 Cluster: N-acetylglucosamine-6-sulfatase; n=2;
           Bacteroides|Rep: N-acetylglucosamine-6-sulfatase -
           Bacteroides thetaiotaomicron
          Length = 558

 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 60/219 (27%), Positives = 96/219 (43%), Gaps = 37/219 (16%)

Query: 284 QSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKV 339
           + Y A  L +DE IG LL+Y++    +  TIIV TSD G+ LGE+G + K   ++   ++
Sbjct: 337 RDYLATVLAVDENIGRLLNYLEKIGELDNTIIVYTSDQGFFLGEHGWFDKRFMYEECQRM 396

Query: 340 PLIFKSPKLIPT-VVHEPVEL-IDIFPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVP 397
           PLI + PK I        + + +D  PT +D   +  E+P  +          +G SL P
Sbjct: 397 PLIIRYPKAIKAGSTSSAISMNVDFAPTFLDFAGV--EVPSDI----------QGASLKP 444

Query: 398 FIENNSNGLEAFAISQCPRPSVYPQKNSDKPRLKDITIMGYSIRTKRYRYTEWISXXXXX 457
            +EN       +  +       YP ++S K          Y IRT+ ++   + +     
Sbjct: 445 VLENEGKTPADWRKAAYYHYYEYPAEHSVKRH--------YGIRTQDFKLIHFYNDIDEW 496

Query: 458 XXXXXXXXYGIELYDHIIDPIESKNLFLVSKYKNIAKVL 496
                      E+YD   DP E  N+F  ++Y    K L
Sbjct: 497 -----------EMYDMKADPREMNNIFGKAEYAKKQKEL 524



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 11/102 (10%)

Query: 25  NILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           NI+F++ DD     +       +  PN++ +   G  F+N +A  AL  PSR  +LTG+ 
Sbjct: 54  NIIFMMTDDHTTQAMSCYGGNLIQTPNMDRIANEGIRFDNCYAVNALSGPSRACILTGKF 113

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK 121
                  D      + S   G+  T P+  ++ GY T  +GK
Sbjct: 114 SHENGFTD------NASTFNGDQQTFPKLLQQAGYQTAMIGK 149


>UniRef50_Q0VM85 Cluster: Putative uncharacterized protein; n=1;
           Alcanivorax borkumensis SK2|Rep: Putative
           uncharacterized protein - Alcanivorax borkumensis
           (strain SK2 / ATCC 700651 / DSM 11573)
          Length = 613

 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 5/93 (5%)

Query: 282 IRQSYYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYSNF-DYA 336
           I + Y  A+ ++D+ +G +L ++     +  TI+V+T DHG    ENG W   S F +  
Sbjct: 430 IFRRYVNASHHLDQQLGRVLGFMKASGRLDNTIVVVTGDHGEEFMENGRWGHNSEFHNEQ 489

Query: 337 LKVPLIFKSPKLIPTVVHEPVELIDIFPTLVDL 369
           + VPL+   P  +P VV  P   +D+ PTL+ +
Sbjct: 490 IHVPLVLAFPGNVPGVVTRPTSHLDVVPTLLPM 522


>UniRef50_A6CBM1 Cluster: Arylsulphatase A; n=1; Planctomyces maris
           DSM 8797|Rep: Arylsulphatase A - Planctomyces maris DSM
           8797
          Length = 497

 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 53/197 (26%), Positives = 90/197 (45%), Gaps = 16/197 (8%)

Query: 25  NILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           NI+ IL DDL +  D   Y       P+++ L   G    + +A   +C+PSR  LLTGR
Sbjct: 34  NIVIILCDDLGY-GDLACYGHPVIKTPHLDQLASEGMRLTDCYASAPVCSPSRAGLLTGR 92

Query: 79  RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYS 138
            P+ L +YD+        + + +  T+ Q  ++ GYDT  VGK    G  ++     P  
Sbjct: 93  TPNRLGVYDWIPEGHP-MHLKRDEVTVAQLLQQAGYDTAHVGKWHCNGMFNSKEQPQP-- 149

Query: 139 WSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLDYAIDFLKK 198
             ++ +        +A +  ++      RN      ++    Q + D + + +  D+ +K
Sbjct: 150 -GDHGFRHWFSTQNNA-LPTHENPNNFVRNGKPLGEIEGFSCQIVAD-EGIRWLSDWREK 206

Query: 199 RNGSKPFFLAIGFHKPH 215
               KPFFL + FH+PH
Sbjct: 207 ---EKPFFLHVCFHEPH 220


>UniRef50_A3ZV95 Cluster: N-acetylgalactosamine 6-sulfatase; n=3;
           Bacteria|Rep: N-acetylgalactosamine 6-sulfatase -
           Blastopirellula marina DSM 3645
          Length = 897

 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 45/149 (30%), Positives = 67/149 (44%), Gaps = 18/149 (12%)

Query: 23  PKNILFILIDDLRHLSDKKVY------LPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           P NI+  L DD   L+D  VY       PN+  L   G TF+ AF     CAPSR +LLT
Sbjct: 23  PPNIVVFLSDD-HTLADSSVYGATDIDTPNMQRLADAGLTFDQAFVASPSCAPSRAALLT 81

Query: 77  GRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
           G  P            R+ +  Q     +P + ++ GY+  S GKV H  +    T DY 
Sbjct: 82  GLMPAR------NGAERNHARPQAEIKKLPAYLQQLGYEVVSFGKVGHYAQ----TPDYG 131

Query: 137 YSWS-EYPYHPPTEMYKDAKVCRNKKTKK 164
           +  +  + YH    + +  K  + +++ K
Sbjct: 132 FDLARHFGYHDDVAVGEAVKWLQARESDK 160



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 12/129 (9%)

Query: 9   LLNGDRVLTSDVETPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQ 63
           ++ G   L S  +TP N++ + IDD     L     + V   NI+ + + G  F N +  
Sbjct: 437 IVYGMPTLLSQAKTPPNVITLFIDDMGWADLSCFGGQDVETTNIDQMAREGLKFTNFYVN 496

Query: 64  QALCAPSRNSLLTGRRPDSLRLYDFYSYWR-DRSNGQGNF-----TTIPQFFKEHGYDTY 117
             +C+PSR +L TG  P   R+  + +  + +   G   +      T+P+   E GY T 
Sbjct: 497 SPICSPSRTALTTGHYPARHRITSYLADRKMNERRGMAQWLDVRAATLPRMLSERGYATG 556

Query: 118 SVGKVFHPG 126
             GK +H G
Sbjct: 557 HFGK-WHLG 564


>UniRef50_A0Q2E6 Cluster: Probable sulfatase; n=1; Clostridium novyi
           NT|Rep: Probable sulfatase - Clostridium novyi (strain
           NT)
          Length = 504

 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 37/110 (33%), Positives = 61/110 (55%), Gaps = 9/110 (8%)

Query: 286 YYAAALYIDELIGILLSYVD----MQKTIIVLTSDHGWSLGENGLWAKYS-NFDYALKVP 340
           YY     +D  IG +L  ++     + TI+V TSDHG   G++ L AK   +++  +K+P
Sbjct: 303 YYGMISMMDHYIGKILDKLEELGMAEDTIVVFTSDHGHFFGQHNLIAKGPFHYEDMIKIP 362

Query: 341 LIFKSPKLIPT--VVHEPVELIDIFPTLVDLTKLSDEIPKCLNHKDTSQL 388
            I + P +IP   V +    L+D+ PTL  L+K+  E+P+ +  KD S +
Sbjct: 363 FIVREPGVIPANKVNNSLQSLVDLTPTL--LSKVGIEVPRTMAGKDESSV 410



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 14/118 (11%)

Query: 24  KNILFILIDDLRHLS-----DKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGR 78
           KNIL I  D  +H +     +K++  PN++ L K G TF+ A+     C P+R +++TG 
Sbjct: 4   KNILLITSDQ-QHWNTIGAFNKEIKTPNLDRLVKEGTTFSRAYCPNPTCTPTRCTMITGL 62

Query: 79  RPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYP 136
            P        +  W   +    N  TI    +++ Y T  VGK        N  + YP
Sbjct: 63  YPSQ------HGGWSLGTKMPENTQTIGNILQDNDYRTALVGKAHFQHNLQN--EKYP 112


>UniRef50_A3H843 Cluster: Sulfatase; n=1; Caldivirga maquilingensis
           IC-167|Rep: Sulfatase - Caldivirga maquilingensis IC-167
          Length = 447

 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 63/219 (28%), Positives = 101/219 (46%), Gaps = 20/219 (9%)

Query: 196 LKKRNGSKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVHRPKEPNIPKDMPLVSWHPWTD 255
           L  R  ++PF L I +  PH P   PK Y ++       +    ++   +   +W     
Sbjct: 151 LINRYKNEPFLLFIHYWDPHAPYIPPKPYAEKFYHGDYSKG---DLVSRLNSTAWGRL-- 205

Query: 256 VRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD----MQKTII 311
           + K   IR L      GV    +   IR  Y + A Y+DE IG L+S ++    ++ T+I
Sbjct: 206 LLKDSWIRDL---INSGVNDPDY---IRALYDSEAAYVDERIGELMSIINNTGLLEDTLI 259

Query: 312 VLTSDHGWSLGENGLWAKYSN-FDYALKVPLIFKSP-KLIPTVVHEPVELIDIFPTLVDL 369
           VLTSDHG  LGE+ ++ ++   +++ +K PLI + P KLI  V     + +  +   V  
Sbjct: 260 VLTSDHGEGLGEHNVYYEHHGLYEWDVKTPLIIRLPDKLIDEVGRGKAKGVK-YDAFVQN 318

Query: 370 TKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNSNGLEA 408
           T ++  I   L  K    +   G SL+  I   S G +A
Sbjct: 319 TDITPTILDSLGLKIPEYM--TGLSLLKVIRGESKGHDA 355



 Score = 38.3 bits (85), Expect = 0.47
 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 9/118 (7%)

Query: 25  NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           N++ I ID LR      L      +PN++ L +    F N +A+     PS  ++ TG  
Sbjct: 7   NVILIAIDTLRADRVGCLGSGYPTMPNVDSLCRDSVAFTNHYAEAIPTHPSFTTIFTGTT 66

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPY 137
           P    ++   S+   +    G+  T+PQ   E GY T +V  +     +  F   Y Y
Sbjct: 67  P---LIHSIVSH-GGKVQLSGSILTLPQILNEAGYLTIAVDNLATHMYAGWFARGYRY 120


>UniRef50_Q4SZ41 Cluster: Chromosome undetermined SCAF11841, whole
           genome shotgun sequence; n=2; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF11841,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 879

 Score = 58.0 bits (134), Expect = 5e-07
 Identities = 83/370 (22%), Positives = 145/370 (39%), Gaps = 28/370 (7%)

Query: 25  NILFILIDDL-RHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLTGRRPDSL 83
           NI+ I+ DD    L   +V       + + G  F NA+    +C PSR+S+LTG+   + 
Sbjct: 40  NIILIMTDDQDMELGSMQVMNKTRRIMEEGGTWFTNAYVTTPMCCPSRSSMLTGKYVHNH 99

Query: 84  RLYDFYSYWRDRS-NGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFTDDYPYSWSEY 142
             Y         S   Q    T   +    GY T   GK  +    S      P  W E+
Sbjct: 100 NTYTNNENCSSMSWQRQHEPRTFGVYLNNTGYRTAFFGKYLNEYNGSY----VPPGWKEW 155

Query: 143 PYHPPTEMYKDAKVCRNKKTKKLERNLICP-VSVKRQPGQSLPDLQSLDYAIDFLKKRNG 201
                   + +  + RN   +K     +C  V V +     L   +S+ Y   + K+   
Sbjct: 156 LGLVKNSRFYNYTLSRNGFREKHGAECVCMCVCVFQDYLTDLITAESMRY-FRYSKRVYP 214

Query: 202 SKPFFLAIGFHKPHIPLKFPKEYLKQMPISKVH-RPK---EPNIPKDM------PLVSWH 251
            +P  + +    PH P     +Y      +  H  P     PN  K        P+   H
Sbjct: 215 HRPVLMVLSHAAPHGPEDSAPQYSTAFQNASQHITPSYNYAPNPDKHWIMRYIGPMKPIH 274

Query: 252 -PWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSY---VDM- 306
             +T++ +R  ++ L ++    +       +      A    +   + +L  Y   V+M 
Sbjct: 275 MEFTNMLQRKRLQTL-LSVDDSMEKAGPADQDASPPGALLRLLTPSVSVLQLYNMLVEMG 333

Query: 307 --QKTIIVLTSDHGWSLGENGL-WAKYSNFDYALKVPLIFKSPKLIPTVVHEPVEL-IDI 362
               T I+ TSDHG+ +G+ GL   K   +++ ++VP   + P +    ++  + L ID+
Sbjct: 334 ELDNTYIIYTSDHGYHIGQFGLVKGKSMPYEFDIRVPFFIRGPNVEQGSINPHIVLNIDL 393

Query: 363 FPTLVDLTKL 372
            PT++D+  L
Sbjct: 394 APTILDIAGL 403


>UniRef50_Q7UHJ9 Cluster: Iduronate-sulfatase or arylsulfatase A;
           n=5; cellular organisms|Rep: Iduronate-sulfatase or
           arylsulfatase A - Rhodopirellula baltica
          Length = 1012

 Score = 58.0 bits (134), Expect = 5e-07
 Identities = 44/135 (32%), Positives = 63/135 (46%), Gaps = 14/135 (10%)

Query: 2   IYVVNIILLNGDRVLTSDVETPKNILFILIDDLRH-----LSDKKVYLPNINFLGKTGAT 56
           +Y V +++L G     +  E P N++ I +DDL +         K+  PNI+ L   G  
Sbjct: 19  LYAVALMMLLGCGTSVA-AERPPNVVLIFVDDLGYGDLGCYGATKLSTPNIDRLAAEGRR 77

Query: 57  FNNAFAQQALCAPSRNSLLTGRRPDSLRLYDFYSYWRDRSNGQG-----NFTTIPQFFKE 111
           F +A +  A+C PSR  LLTG+ P  +R       W       G     N  TI + FK 
Sbjct: 78  FTDAHSASAVCTPSRYGLLTGQYP--VRAMGGQGIWGPLPTTSGLIIDTNTKTIGKVFKN 135

Query: 112 HGYDTYSVGKVFHPG 126
            GY T  +GK +H G
Sbjct: 136 KGYATACLGK-WHLG 149



 Score = 48.4 bits (110), Expect = 4e-04
 Identities = 54/215 (25%), Positives = 86/215 (40%), Gaps = 30/215 (13%)

Query: 22  TPKNILFILIDD-----LRHLSDKKVYLPNINFLGKTGATFNNAFAQQALCAPSRNSLLT 76
           T  N + IL DD     L     K V  P I+ +   G+   + +    +C PSR  L+T
Sbjct: 569 TKPNFIVILTDDQGYGDLSCFGAKHVDTPRIDQMAAEGSRLTSFYVAAPVCTPSRAGLMT 628

Query: 77  GRRPDSLRLYDFYSYW----RDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFHPGKSSNFT 132
           G  P  + +    ++      D      +  TI +  K  GY T   GK +H G    F 
Sbjct: 629 GCYPKRIDMAMGSNFGVLLAGDPKGLHPDEITIAEVLKTAGYRTGMFGK-WHLGDQPEFL 687

Query: 133 ------DDY---PYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSL 183
                 D++   PYS   +P+HP    Y    +        L+ + +    ++  P    
Sbjct: 688 PTKQGFDEFFGIPYSHDIHPFHPRQNHYHFPPL------PLLQNDTV----IEMDPDADF 737

Query: 184 PDLQSLDYAIDFLKKRNGSKPFFLAIGFHKPHIPL 218
              +  + A+ F+ +RN  +PFFL +    PH PL
Sbjct: 738 LTKRLTEQAVSFI-ERNKDQPFFLYLPHPIPHAPL 771


>UniRef50_Q7NFU3 Cluster: Gll3431 protein; n=2; Gloeobacter
           violaceus|Rep: Gll3431 protein - Gloeobacter violaceus
          Length = 521

 Score = 58.0 bits (134), Expect = 5e-07
 Identities = 92/401 (22%), Positives = 169/401 (42%), Gaps = 42/401 (10%)

Query: 25  NILFILIDDLR--HLSD--KKVYLPNI-NFLGKTGATFNNAFAQQALCAPSRNSLLTGRR 79
           +I+ +  DDL    L+D  ++  LP I N L + G  F N+F   +LC PSR++ LTG+ 
Sbjct: 45  SIVVVTADDLSTMELNDGLERGLLPAIQNRLVEEGTVFANSFVSYSLCCPSRSTFLTGQY 104

Query: 80  PDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGKVFH-----PGKSSNFTDD 134
             +  +          +    + +T+  +  + GY T  +GK  +       KSS   D 
Sbjct: 105 SHNHGVQG-NGPPIGGAVALRDDSTLATWLDDAGYVTGFLGKYLNGYGANKDKSSPRDDA 163

Query: 135 --YPYSWSEYP--YHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSLD 190
              P  W  +     P T    + K+  N +      +   P      P +   D+ S  
Sbjct: 164 TYVPPGWDVWQGLVDPTTYQVYNFKINENGRVANYGTDQAEP------PEEYQTDVLSAR 217

Query: 191 YAIDFLKKR-NGSKPFFLAIGFHKPHIPLKFPKEY-LKQMPISKVH-RPKEPNIPKDMPL 247
            A++F+++  +G  PFFL +    PH  L+  +   +   P + +   P+       +PL
Sbjct: 218 -AVNFVEQYGSGDAPFFLWVNPIAPHFELRGTRRCTVNPRPQNSIRPAPRHAGSAAAVPL 276

Query: 248 VSWHPWTDVRKRDDIRRLNITFPFGVMPTKWTLKIRQSYYAAALYIDELIGILLSYVD-- 305
                + +    D    +                + ++   A   +D+L+  L   ++  
Sbjct: 277 PRGPAFNEQDVSDKPTWVQQNPAMSERTIDCLQNLYRNRLEAMRAVDDLVAALFDALERT 336

Query: 306 --MQKTIIVLTSDHGWSLGENGLWAKYSNFDYALKVPLIFKSPKL-IPTVVHEPVELIDI 362
             +  TI++LTSD+G+ LG++ L AK   ++ +++VPL+ + P    P  V E V   D+
Sbjct: 337 GALGDTIVLLTSDNGYLLGQHRLTAKVLPYEESIRVPLLVRVPDAGAPGRVDELVINNDL 396

Query: 363 FPTLVDLTKLSDEIPKCLNHKDTSQLCFEGKSLVPFIENNS 403
            PT+     +            T  L  +G+SLVP + +++
Sbjct: 397 APTIAAWAGV------------TPDLAVDGRSLVPLLADST 425


>UniRef50_A6DG52 Cluster: Arylsulphatase A; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Arylsulphatase A - Lentisphaera
           araneosa HTCC2155
          Length = 419

 Score = 58.0 bits (134), Expect = 5e-07
 Identities = 61/217 (28%), Positives = 94/217 (43%), Gaps = 31/217 (14%)

Query: 17  TSDVETPK-NILFILIDDLRH-----LSDKKVYLPNINFLGKTGATFNNAFAQQALCAPS 70
           T D +  K NI+ I+ DD+ +             P +N L +TG  FN+ ++ + +C PS
Sbjct: 7   TLDAQASKPNIILIMADDIAYDNIACYGSNYFKTPRLNQLAQTGVKFNHCYS-EPVCTPS 65

Query: 71  RNSLLTGRRPDSLRLYDFYSYWRDRSNGQGNFTTIPQFFKEHGYDTYSVGK-VFHPGKSS 129
           R  ++TGR  D +R Y  +     +       TT     KE GY T   GK   + G+  
Sbjct: 66  RVKIMTGR--DGIRNYVGFGILDKKE------TTFGTMMKEAGYATAVAGKWQLYTGRKG 117

Query: 130 NFTDDYPYSWSEYPYHPPTEMYKDAKVCRNKKTKKLERNLICPVSVKRQPGQSLPDLQSL 189
           +   D  +       +P TE  +       +  KK+      PV+    P    PD+   
Sbjct: 118 SLAPDCGFDTYCLWSYPGTERSRFWNPSLIRDGKKV------PVT----PNSYGPDI-CT 166

Query: 190 DYAIDFLKKRNGSKPFFL---AIGFHKPHIPLKFPKE 223
           D+ IDF+KK N S+PFF     +  H P +P    K+
Sbjct: 167 DFIIDFIKK-NKSQPFFAYYPMLLVHSPFVPTPDSKD 202


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.321    0.139    0.430 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 609,308,224
Number of Sequences: 1657284
Number of extensions: 27273367
Number of successful extensions: 55686
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 469
Number of HSP's successfully gapped in prelim test: 399
Number of HSP's that attempted gapping in prelim test: 53372
Number of HSP's gapped (non-prelim): 1954
length of query: 508
length of database: 575,637,011
effective HSP length: 104
effective length of query: 404
effective length of database: 403,279,475
effective search space: 162924907900
effective search space used: 162924907900
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 75 (34.3 bits)

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