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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001290-TA|BGIBMGA001290-PA|IPR002083|MATH,
IPR008974|TRAF-like
         (359 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D55C72 Cluster: PREDICTED: similar to CG10961-PA...   318   1e-85
UniRef50_Q9UAC4 Cluster: TRAF6; n=4; Sophophora|Rep: TRAF6 - Dro...   245   2e-63
UniRef50_Q7PR29 Cluster: ENSANGP00000017658; n=1; Anopheles gamb...   227   3e-58
UniRef50_UPI0000DB7BF4 Cluster: PREDICTED: similar to TNF-recept...   191   2e-47
UniRef50_Q7SXX1 Cluster: TNF receptor-associated factor 6; n=14;...   126   9e-28
UniRef50_Q1RPY5 Cluster: Zinc finger protein; n=1; Ciona intesti...   120   8e-26
UniRef50_A2TK70 Cluster: Tumor necrosis factor receptor-associat...   113   7e-24
UniRef50_UPI0000E48AC9 Cluster: PREDICTED: similar to TRAF6; n=1...   112   1e-23
UniRef50_Q9Y4K3 Cluster: TNF receptor-associated factor 6; n=18;...   111   4e-23
UniRef50_A2SVB5 Cluster: TRAF6; n=1; Chlamys farreri|Rep: TRAF6 ...   105   2e-21
UniRef50_A7RI91 Cluster: Predicted protein; n=1; Nematostella ve...   101   4e-20
UniRef50_UPI0000E1EFBF Cluster: PREDICTED: TNF receptor-associat...    97   6e-19
UniRef50_A7SER6 Cluster: Predicted protein; n=1; Nematostella ve...    94   4e-18
UniRef50_Q32S42 Cluster: Tumor necrosis factor receptor associat...    93   1e-17
UniRef50_UPI00006A1D59 Cluster: TNF receptor-associated factor 2...    82   2e-14
UniRef50_A7RRA4 Cluster: Predicted protein; n=1; Nematostella ve...    80   8e-14
UniRef50_Q12933 Cluster: TNF receptor-associated factor 2; n=41;...    80   8e-14
UniRef50_O00463 Cluster: TNF receptor-associated factor 5; n=20;...    78   3e-13
UniRef50_Q50IU9 Cluster: Tumour necrosis receptor-associated fac...    77   5e-13
UniRef50_UPI0000E4A8D0 Cluster: PREDICTED: similar to CD40-assoc...    74   5e-12
UniRef50_Q9BUZ4 Cluster: TNF receptor-associated factor 4; n=35;...    74   7e-12
UniRef50_Q4S289 Cluster: Chromosome undetermined SCAF14764, whol...    73   2e-11
UniRef50_Q13077 Cluster: TNF receptor-associated factor 1; n=11;...    72   3e-11
UniRef50_P39428 Cluster: TNF receptor-associated factor 1; n=7; ...    71   6e-11
UniRef50_A7RGK7 Cluster: Predicted protein; n=2; Nematostella ve...    70   8e-11
UniRef50_A5X2W4 Cluster: TNF receptor associated factor 1; n=2; ...    69   2e-10
UniRef50_UPI00006A045C Cluster: TNF receptor-associated factor 3...    69   2e-10
UniRef50_UPI00006A0459 Cluster: TNF receptor-associated factor 3...    69   2e-10
UniRef50_A7SBN4 Cluster: Predicted protein; n=1; Nematostella ve...    69   2e-10
UniRef50_Q706I7 Cluster: TNF-receptor-associated factor 1; n=1; ...    68   3e-10
UniRef50_UPI0000E4A50D Cluster: PREDICTED: similar to TRAF4 prot...    68   4e-10
UniRef50_Q13114 Cluster: TNF receptor-associated factor 3; n=35;...    68   4e-10
UniRef50_A2TK67 Cluster: Tumor necrosis factor receptor-associat...    66   1e-09
UniRef50_UPI00015A66C8 Cluster: TNF receptor-associated factor 5...    65   3e-09
UniRef50_Q4TBW0 Cluster: Chromosome undetermined SCAF7089, whole...    64   4e-09
UniRef50_UPI00005845EF Cluster: PREDICTED: similar to zinc finge...    64   5e-09
UniRef50_A7STV3 Cluster: Predicted protein; n=2; Nematostella ve...    64   5e-09
UniRef50_UPI00015A639D Cluster: hypothetical protein LOC445119; ...    64   7e-09
UniRef50_A7SX78 Cluster: Predicted protein; n=5; Nematostella ve...    64   7e-09
UniRef50_UPI0000ECA75E Cluster: TNF receptor-associated factor 1...    62   2e-08
UniRef50_A7S6K0 Cluster: Predicted protein; n=1; Nematostella ve...    62   2e-08
UniRef50_A7RG36 Cluster: Predicted protein; n=1; Nematostella ve...    61   4e-08
UniRef50_A2TK68 Cluster: Tumor necrosis factor receptor-associat...    61   4e-08
UniRef50_UPI000056A9B8 Cluster: TNF receptor-associated factor 1...    60   7e-08
UniRef50_UPI0000E4656D Cluster: PREDICTED: similar to TRAFamn; n...    60   1e-07
UniRef50_Q9XYR0 Cluster: CG3048-PA, isoform A; n=8; Endopterygot...    59   2e-07
UniRef50_UPI0000F2106A Cluster: PREDICTED: similar to TRAF5; n=1...    58   3e-07
UniRef50_A7SM27 Cluster: Predicted protein; n=1; Nematostella ve...    57   8e-07
UniRef50_Q4RF33 Cluster: Chromosome 14 SCAF15120, whole genome s...    56   1e-06
UniRef50_A7RJK8 Cluster: Predicted protein; n=1; Nematostella ve...    56   1e-06
UniRef50_A7S4Z7 Cluster: Predicted protein; n=2; Nematostella ve...    55   2e-06
UniRef50_Q4KS49 Cluster: Tumor necrosis factor type 2 receptor a...    54   8e-06
UniRef50_Q16819 Cluster: Meprin A subunit alpha precursor; n=38;...    48   3e-04
UniRef50_A7SJA2 Cluster: Predicted protein; n=1; Nematostella ve...    46   0.001
UniRef50_Q70AC9 Cluster: TNF-receptor associated factor 6; n=1; ...    44   0.005
UniRef50_Q16820 Cluster: Meprin A subunit beta precursor; n=39; ...    44   0.006
UniRef50_Q1RQ04 Cluster: Zinc finger protein; n=1; Ciona intesti...    43   0.014
UniRef50_UPI0000D55C6F Cluster: PREDICTED: similar to CG4394-PC,...    42   0.025
UniRef50_O62248 Cluster: Putative uncharacterized protein trf-1;...    42   0.025
UniRef50_Q9N586 Cluster: Putative uncharacterized protein; n=2; ...    42   0.033
UniRef50_UPI00006CBFFF Cluster: hypothetical protein TTHERM_0041...    40   0.100
UniRef50_Q4SV26 Cluster: Chromosome 8 SCAF13813, whole genome sh...    40   0.13 
UniRef50_Q9VJW5 Cluster: CG9014-PA; n=2; Sophophora|Rep: CG9014-...    40   0.13 
UniRef50_UPI00015B5CBE Cluster: PREDICTED: similar to LOC1000366...    39   0.23 
UniRef50_UPI0000E4915D Cluster: PREDICTED: similar to TRAF6; n=1...    38   0.40 
UniRef50_Q54NN4 Cluster: Putative uncharacterized protein; n=1; ...    38   0.40 
UniRef50_UPI00015B6061 Cluster: PREDICTED: similar to tnf recept...    38   0.53 
UniRef50_Q54FB9 Cluster: Putative uncharacterized protein; n=1; ...    37   0.70 
UniRef50_A7SBQ8 Cluster: Predicted protein; n=2; Nematostella ve...    37   0.70 
UniRef50_Q8I451 Cluster: Putative uncharacterized protein PFE025...    36   1.2  
UniRef50_Q54RH9 Cluster: Putative uncharacterized protein; n=1; ...    36   1.2  
UniRef50_Q8IDB9 Cluster: Putative uncharacterized protein PF13_0...    36   1.6  
UniRef50_Q8IBU8 Cluster: Putative uncharacterized protein PF07_0...    36   1.6  
UniRef50_Q8I5C6 Cluster: Putative uncharacterized protein; n=1; ...    36   1.6  
UniRef50_A0D7J7 Cluster: Chromosome undetermined scaffold_4, who...    36   1.6  
UniRef50_Q5KB27 Cluster: Putative uncharacterized protein; n=1; ...    36   1.6  
UniRef50_UPI0000E87FE6 Cluster: hypothetical protein MB2181_0416...    36   2.1  
UniRef50_Q8IHR0 Cluster: Putative uncharacterized protein; n=1; ...    36   2.1  
UniRef50_Q24GI4 Cluster: Putative uncharacterized protein; n=1; ...    36   2.1  
UniRef50_Q23RX6 Cluster: Myb-like DNA-binding domain containing ...    36   2.1  
UniRef50_A7S0G1 Cluster: Predicted protein; n=1; Nematostella ve...    36   2.1  
UniRef50_A5DDS4 Cluster: Putative uncharacterized protein; n=1; ...    36   2.1  
UniRef50_Q7QFB1 Cluster: ENSANGP00000010011; n=1; Anopheles gamb...    35   2.8  
UniRef50_A7RGH1 Cluster: Predicted protein; n=1; Nematostella ve...    35   2.8  
UniRef50_P22265 Cluster: Protein teashirt; n=3; Sophophora|Rep: ...    35   2.8  
UniRef50_UPI00006CFBCB Cluster: hypothetical protein TTHERM_0048...    35   3.7  
UniRef50_Q24E40 Cluster: Leucine Rich Repeat family protein; n=1...    35   3.7  
UniRef50_Q232U4 Cluster: Putative uncharacterized protein; n=1; ...    35   3.7  
UniRef50_Q22P57 Cluster: Putative uncharacterized protein; n=1; ...    35   3.7  
UniRef50_Q22EZ0 Cluster: Putative uncharacterized protein; n=1; ...    35   3.7  
UniRef50_A0DXA7 Cluster: Chromosome undetermined scaffold_68, wh...    35   3.7  
UniRef50_A0DAY9 Cluster: Chromosome undetermined scaffold_43, wh...    35   3.7  
UniRef50_Q0CDL1 Cluster: Putative uncharacterized protein; n=1; ...    35   3.7  
UniRef50_Q5A216 Cluster: Probable kinetochore protein NDC80; n=1...    35   3.7  
UniRef50_UPI00015B491A Cluster: PREDICTED: similar to conserved ...    34   5.0  
UniRef50_UPI00005885C0 Cluster: PREDICTED: similar to TRAF4 prot...    34   5.0  
UniRef50_UPI0000660B2D Cluster: Meprin A subunit alpha precursor...    34   5.0  
UniRef50_Q9NGW8 Cluster: Developmental protein DG1037; n=2; Dict...    34   5.0  
UniRef50_Q557K0 Cluster: Putative uncharacterized protein; n=2; ...    34   5.0  
UniRef50_Q54LU4 Cluster: Putative uncharacterized protein; n=1; ...    34   5.0  
UniRef50_Q23RY6 Cluster: Putative uncharacterized protein; n=1; ...    34   5.0  
UniRef50_A0CJC8 Cluster: Chromosome undetermined scaffold_2, who...    34   5.0  
UniRef50_P10071 Cluster: Zinc finger protein GLI3; n=44; Eumetaz...    34   5.0  
UniRef50_UPI00006CFC12 Cluster: hypothetical protein TTHERM_0053...    34   6.5  
UniRef50_UPI00006CA3DB Cluster: hypothetical protein TTHERM_0052...    34   6.5  
UniRef50_Q9PQX1 Cluster: MBA N-terminal paralog; n=1; Ureaplasma...    34   6.5  
UniRef50_Q7VFK1 Cluster: Putative uncharacterized protein; n=1; ...    34   6.5  
UniRef50_Q8IBH0 Cluster: Putative uncharacterized protein MAL7P1...    34   6.5  
UniRef50_Q7RFF8 Cluster: Putative uncharacterized protein PY0474...    34   6.5  
UniRef50_Q55GA0 Cluster: Putative uncharacterized protein; n=1; ...    34   6.5  
UniRef50_Q54RG7 Cluster: Putative uncharacterized protein; n=1; ...    34   6.5  
UniRef50_Q54PJ2 Cluster: Sphingosine kinase; n=2; Dictyostelium ...    34   6.5  
UniRef50_Q54NA9 Cluster: Putative uncharacterized protein; n=1; ...    34   6.5  
UniRef50_Q9VVV9 Cluster: Protein naked cuticle; n=2; Drosophila ...    34   6.5  
UniRef50_Q81ZL2 Cluster: SMC protein; n=4; Coxiella burnetii|Rep...    33   8.7  
UniRef50_A4CKU3 Cluster: OmpA family protein; n=1; Robiginitalea...    33   8.7  
UniRef50_Q8ILJ3 Cluster: Putative uncharacterized protein; n=1; ...    33   8.7  
UniRef50_Q8IKW4 Cluster: Putative uncharacterized protein; n=1; ...    33   8.7  
UniRef50_Q8IDG0 Cluster: Putative uncharacterized protein PF13_0...    33   8.7  
UniRef50_Q6LF05 Cluster: Putative uncharacterized protein; n=1; ...    33   8.7  
UniRef50_Q54VP0 Cluster: Putative uncharacterized protein; n=1; ...    33   8.7  
UniRef50_Q54R73 Cluster: Putative uncharacterized protein; n=1; ...    33   8.7  
UniRef50_Q23CN2 Cluster: Putative uncharacterized protein; n=1; ...    33   8.7  
UniRef50_A7S9A1 Cluster: Predicted protein; n=1; Nematostella ve...    33   8.7  
UniRef50_A2EZQ0 Cluster: Putative uncharacterized protein; n=1; ...    33   8.7  
UniRef50_P42527 Cluster: Myosin heavy chain kinase A; n=2; Dicty...    33   8.7  

>UniRef50_UPI0000D55C72 Cluster: PREDICTED: similar to CG10961-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG10961-PA - Tribolium castaneum
          Length = 398

 Score =  318 bits (781), Expect = 1e-85
 Identities = 146/348 (41%), Positives = 231/348 (66%), Gaps = 12/348 (3%)

Query: 12  CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYNQPE 71
           CPIDN  L   VDIFPDN+T+REI +Q+  CP   +GC  +++PLD++ H+  C+Y  PE
Sbjct: 63  CPIDNTKLEKGVDIFPDNFTRREISQQKTKCPNLVRGCLEELSPLDVETHLLTCQYKPPE 122

Query: 72  TSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNAN 131
                ++   C+F   GC++ F+ + E+ +HL      H+NLL  AYS+  IN+  ++A 
Sbjct: 123 LPENEKLR--CAFVEFGCEDKFEDEPELQRHLEQYIHKHLNLLSQAYSKFTINSPSTSAI 180

Query: 132 MDTKEQEAMALWDAPDKDGNQTSSPPLNNTSALIRALYERVVVLEQRNREQDIVIANISK 191
                Q+A   WD P K+    SS   +N + L++ALYE+ V+LEQ+ REQDI+IAN+S+
Sbjct: 181 A----QQAN-FWDPPSKNDTSVSSNH-DNVNGLLKALYEKAVLLEQKTREQDIIIANMSE 234

Query: 192 QLSAFAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYR 251
           Q+S+  ++  K    M LRYC G Y+W  ++FK +++AM  D   M YSPGFYT+ NGYR
Sbjct: 235 QISSLNLSMSK----MHLRYCNGCYLWYFNDFKNKINAMRNDSRIMHYSPGFYTAANGYR 290

Query: 252 FCVRLNISPQNTHFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNT 311
            C+RLN+SP++ ++ A+ +H+MKTE+D+ L+WPF+GR++  LV+ + P  + ++TMM+  
Sbjct: 291 LCIRLNLSPKDPNYIAILIHVMKTEHDNALDWPFSGRLTITLVHPLQPFHNIKETMMTRP 350

Query: 312 NLKAFSKPATEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNIKCV 359
            L AF KP  ++  +GFGYTE+A++ ++   G+V+++ L+I+V  + V
Sbjct: 351 ELDAFKKPVQDMNPKGFGYTEFALIEELFSQGYVENNHLLIKVQAQPV 398


>UniRef50_Q9UAC4 Cluster: TRAF6; n=4; Sophophora|Rep: TRAF6 -
           Drosophila melanogaster (Fruit fly)
          Length = 475

 Score =  245 bits (599), Expect = 2e-63
 Identities = 133/357 (37%), Positives = 196/357 (54%), Gaps = 21/357 (5%)

Query: 8   NSGHCPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEY 67
           N+  CP+DN  LS + DIFPDNYT+REI++ + +CP S+ GC+V  +P++L  H+  C Y
Sbjct: 135 NNQCCPMDNKRLSAEHDIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPY 194

Query: 68  N---QPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKIN 124
               +P+    P   I C F   G  ET    +++ +HL  D   HM L++ A+ +  I 
Sbjct: 195 RRQQEPQEEKCPFAKIKCDF--VGRPET----NQLEEHLKADMPHHMQLMLQAFQQTAIA 248

Query: 125 NDMSNANMDTKEQEAMALWDAPDKDGNQTSSPPLNN--TSALIRALYERVVVLEQRNREQ 182
               +     K   + A  +           PP  N     +++ +Y+R+VVLEQR REQ
Sbjct: 249 TWQPH-----KPSTSGAAVENGHGQQQLPPPPPYANGVDEQIVQTMYQRIVVLEQRTREQ 303

Query: 183 DIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPG 242
           +  + N+ KQL        +Q   +  RY  G  VWRI+     +  +  +    +YS  
Sbjct: 304 ETRLENMQKQLRL-----ARQQAPVDSRYSNGTIVWRIEQLGALVARLRANANNQVYSHE 358

Query: 243 FYTSPNGYRFCVRLNISPQNTHFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELS 302
            YTSP+GY+FC RLNI P+  H  +LHVHLM++END  L+WPF GRI   +V+     LS
Sbjct: 359 CYTSPHGYKFCARLNIQPRKPHVLSLHVHLMQSENDYHLDWPFKGRIKLCMVHPADATLS 418

Query: 303 QRDTMMSNTNLKAFSKPATEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNIKCV 359
           Q DT+M+   + AF KP   I  RGFG+ EYA + ++I+ GF  DD L+I++ I  V
Sbjct: 419 QHDTIMTKPEILAFHKPREAISTRGFGFLEYANISNIIQLGFCADDRLLIKIEINIV 475


>UniRef50_Q7PR29 Cluster: ENSANGP00000017658; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000017658 - Anopheles gambiae
           str. PEST
          Length = 374

 Score =  227 bits (555), Expect = 3e-58
 Identities = 119/351 (33%), Positives = 192/351 (54%), Gaps = 19/351 (5%)

Query: 9   SGHCPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYN 68
           + +CP+DN  L +K DIFPDN T+REI + +  CP S +GC  +++P D+D H+  C + 
Sbjct: 43  NSNCPLDNEPLDIKCDIFPDNCTRREISQIKKPCPNSMRGCGEQLSPTDIDTHLRQCPFA 102

Query: 69  QPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMS 128
               S       PC F    CK     +  M+ H+ +D Q H+ +     +     + ++
Sbjct: 103 MSRQSQ------PCPFARVKCKFVAPDEAAMSAHIASDCQQHLQV-----ARSPCVSALT 151

Query: 129 NANMDTKEQEAMALWDAPDKDGNQTSSPPLNNTSALIRALYERVVVLEQRNREQDIVIAN 188
               +       +      ++     S  ++    L+R++YER+V+LEQ   E  I+   
Sbjct: 152 VTKFEFSPFTICSYCSRRTQEATIGISFGIHRPKTLVRSMYERIVILEQ---EVHILGIK 208

Query: 189 ISKQLSAFAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPN 248
           +SKQ     +   K N E+  RY  G  +W++D+F  ++++M+ +   M YS   YTSP+
Sbjct: 209 LSKQ----EIQLTKLNQEVDPRYSGGVLLWKLDDFSNKIESMVANSNCMFYSSEAYTSPH 264

Query: 249 GYRFCVRLNISPQNTHFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMM 308
           GY+FC R+N+SP+      LHVHLM++END  LEWPF GRI   L+N   PELSQ DT+M
Sbjct: 265 GYKFCARINVSPRTKDSIGLHVHLMQSENDYHLEWPFKGRIKITLLNVRSPELSQHDTIM 324

Query: 309 SNTNLKAFSKPATEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNIKCV 359
           S   + AF +P  +I  RGFG+ E+A + D++   F  ++ ++I++ +  V
Sbjct: 325 SKPEILAFHRPNQDISPRGFGFLEFAKIKDILAK-FADNNTVVIKIQMNIV 374


>UniRef50_UPI0000DB7BF4 Cluster: PREDICTED: similar to
           TNF-receptor-associated factor 2 CG10961-PA; n=1; Apis
           mellifera|Rep: PREDICTED: similar to
           TNF-receptor-associated factor 2 CG10961-PA - Apis
           mellifera
          Length = 359

 Score =  191 bits (466), Expect = 2e-47
 Identities = 88/192 (45%), Positives = 127/192 (66%), Gaps = 3/192 (1%)

Query: 168 LYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRL 227
           LYER+VVLEQ+NRE  I ++N   QL+    +      EM LR C G Y+WR+ +F  +L
Sbjct: 155 LYERIVVLEQQNRELSITVSNQKTQLTTLQTSLRFNQEEMFLRSCNGVYIWRLHSFHEKL 214

Query: 228 DAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNTHFFALHVHLMKTENDDCLEWPFNG 287
           ++M+ D  KM YSPGFYTSPNGY+ C R+N+S ++  F +L +H+MK+ENDD L+WPFNG
Sbjct: 215 ESMMNDSLKMFYSPGFYTSPNGYKICARINVSSKDPEFLSLLLHIMKSENDDGLDWPFNG 274

Query: 288 RISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFGYTEYAVLGDVIRNGFVKD 347
            + FVLV+ +  E   R+   S  +L+AF KP  E+  R FGYTE+  + D++   F+++
Sbjct: 275 TMYFVLVHPLNSERDIREITSSRPDLEAFRKPICELNKRSFGYTEFVRIRDLL--DFLQN 332

Query: 348 DVLIIRVNIKCV 359
           D L  R+ + CV
Sbjct: 333 DCLTFRIEV-CV 343



 Score = 87.0 bits (206), Expect = 7e-16
 Identities = 37/89 (41%), Positives = 55/89 (61%), Gaps = 3/89 (3%)

Query: 12  CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYNQPE 71
           CP+D+  L  + D+F D YT REI +QR  CP+   GC +KV+P+D++ HI  C Y +  
Sbjct: 69  CPVDSKPLKSESDLFRDLYTSREISQQRTPCPYQQFGCEIKVSPVDMETHINECTYKRTL 128

Query: 72  TSSQPEIHIPCSFKPAGCKETFDSQDEMN 100
             SQ   ++ C FK  GC ETF ++ ++N
Sbjct: 129 PDSQ---NVYCPFKKVGCMETFPTEKDLN 154


>UniRef50_Q7SXX1 Cluster: TNF receptor-associated factor 6; n=14;
           Euteleostomi|Rep: TNF receptor-associated factor 6 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 542

 Score =  126 bits (304), Expect = 9e-28
 Identities = 85/285 (29%), Positives = 140/285 (49%), Gaps = 13/285 (4%)

Query: 80  IPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINN-DMSNANMDTKEQE 138
           + C+F   GC+E   +++E+ QH+   TQ HM  +        +NN  M +A   +   +
Sbjct: 241 VACTFSTFGCREKM-TRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHSSSDD 299

Query: 139 AMALWDAPDKDGNQTSSPPLNNTSALIRALYERVVVLEQRNREQDI---VIANISKQLSA 195
             A   +PD    Q     LN    ++  L  R+V  +Q+ RE  I      N   +L  
Sbjct: 300 RGASARSPDSC--QCKQELLNLRETVLE-LEGRLVRQDQQIRELCIHNDTQKNQVTELRR 356

Query: 196 FAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVR 255
             V+  +   E+  +   G YVWR++NF   L         +L+SP FYT   GY+ C+R
Sbjct: 357 KLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLR 416

Query: 256 LNI----SPQNTHFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNT 311
           L++    +P+ ++F +L VH M+ E D  L WP  G I   +++QV  +    + M +  
Sbjct: 417 LHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQVEGQ-HHIEVMETKP 475

Query: 312 NLKAFSKPATEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
           +L+AF +P      +GFGY  +  L  + + GFVK+DVL++R  +
Sbjct: 476 DLQAFQRPTVMRNPKGFGYVTFLHLQALRQRGFVKEDVLLVRCEV 520



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 4/67 (5%)

Query: 2   LQKGSLNSGH-CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDA 60
           ++K   ++G  CP+DN  + ++  +FPDN+ KREI    + C  S  GC+ K+    L+ 
Sbjct: 95  IRKSIRDTGQKCPVDN-EVLLEEQLFPDNFAKREILSLTVKC--SNFGCSEKMELRQLEK 151

Query: 61  HIAVCEY 67
           H++ C +
Sbjct: 152 HLSQCRF 158


>UniRef50_Q1RPY5 Cluster: Zinc finger protein; n=1; Ciona
           intestinalis|Rep: Zinc finger protein - Ciona
           intestinalis (Transparent sea squirt)
          Length = 579

 Score =  120 bits (288), Expect = 8e-26
 Identities = 66/157 (42%), Positives = 90/157 (57%), Gaps = 12/157 (7%)

Query: 209 LRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNI----SPQNTH 264
           LR C G Y W+I ++     A       +L+SPGFYTSP GYR C+R N+    S Q TH
Sbjct: 418 LRCCNGLYYWKIKDYAQLRRAACLGEMPVLHSPGFYTSPQGYRMCIRANLDGVESAQGTH 477

Query: 265 FFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPEL-SQR----DTMMSNTNLKAFSKP 319
             +L VHLMK + DD L WPF G I+  ++NQ   EL SQR    + + S  NL AF +P
Sbjct: 478 -LSLFVHLMKGDFDDVLPWPFCGSITLTVINQ--KELPSQRAHVSEMLESRANLMAFQRP 534

Query: 320 ATEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
            TE   +G+GY ++  L  +   GF+K D L+I+  +
Sbjct: 535 ITERNQKGYGYIDFLPLNLIETEGFIKSDTLVIKAQV 571



 Score = 36.7 bits (81), Expect = 0.93
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%)

Query: 69  QPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINND 126
           Q  +S  P+  I C F   GC + +   D +  H+ N TQ H+  L++    ++  ND
Sbjct: 206 QHMSSECPQAPIKCVFDKVGCHQQYPRHD-IKTHMENTTQIHLQYLLSFIMNLQKQND 262


>UniRef50_A2TK70 Cluster: Tumor necrosis factor receptor-associated
           factor 6; n=1; Branchiostoma belcheri|Rep: Tumor
           necrosis factor receptor-associated factor 6 -
           Branchiostoma belcheri (Amphioxus)
          Length = 642

 Score =  113 bits (272), Expect = 7e-24
 Identities = 67/217 (30%), Positives = 111/217 (51%), Gaps = 11/217 (5%)

Query: 151 NQTSSPPLNNTSALI--RALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEML 208
           ++ S  P +  S+++  R+L  +V   E +  EQ   I  +  +L +      +   +  
Sbjct: 425 SRDSGAPRSEDSSMVDARSLRTKVHNQEAKIVEQQHYIRELELKLGSLQQKYFELEEKTR 484

Query: 209 LRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNI----SPQNTH 264
            R C G Y+WRI  +       +     + +S GFYTS  GY+ CVR+N+    S   TH
Sbjct: 485 ERMCNGTYIWRIKEYSKLRQQAVNGAATVRHSSGFYTSYYGYKLCVRVNLNGVDSAHGTH 544

Query: 265 FFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQ----RDTMMSNTNLKAFSKPA 320
             +L +H M  ENDD LEWPF G+I+  +++Q      Q     +T++S  +  AF +P 
Sbjct: 545 -ISLFIHFMMGENDDILEWPFQGKITLSILDQNSNPAQQAKHITETLVSKPSYAAFQRPT 603

Query: 321 TEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNIK 357
           T    +GFGY E+A+L  +    ++K+D LII+  ++
Sbjct: 604 TLRNHKGFGYMEFALLRSLENGQYIKNDTLIIKCMVQ 640



 Score = 54.0 bits (124), Expect = 6e-06
 Identities = 37/118 (31%), Positives = 58/118 (49%), Gaps = 17/118 (14%)

Query: 12  CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYNQPE 71
           CP+DN  L+ +  IFPDN+ KREI   R+ C  S KG   K+    LD+H++ C +    
Sbjct: 89  CPVDNTPLTEE-QIFPDNFAKREILALRVKC--SNKGRKEKIELTYLDSHLSTCNF---- 141

Query: 72  TSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSN 129
                   + C   P  C +TF  +D + +HLNND    +    + + E+  +   S+
Sbjct: 142 ------AFVRC---PLECGDTFWRKD-IPEHLNNDCPRRLVKCPHCFKEIPFDQQESH 189



 Score = 39.1 bits (87), Expect = 0.17
 Identities = 17/47 (36%), Positives = 24/47 (51%)

Query: 76  PEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMK 122
           P   + C FKP GC      +  + +HL   TQ H+ LL+NA   +K
Sbjct: 221 PRAPVLCVFKPVGCNVEKMERRNLAEHLQEFTQVHLRLLLNALEGLK 267


>UniRef50_UPI0000E48AC9 Cluster: PREDICTED: similar to TRAF6; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           TRAF6 - Strongylocentrotus purpuratus
          Length = 462

 Score =  112 bits (270), Expect = 1e-23
 Identities = 62/195 (31%), Positives = 108/195 (55%), Gaps = 12/195 (6%)

Query: 170 ERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRLDA 229
           ++V+ LE +   +D  IA +  ++ +      ++  ++      G +VWR+  +     +
Sbjct: 267 QKVIELESKAARKDSEIATLRNEVHSL----QEETKDLREHVANGIFVWRLRKYSELRVS 322

Query: 230 MLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNTH---FFALHVHLMKTENDDCLEWPFN 286
             +    + +S GFYT   GYR CVR+NI+   T    + +L VH M+ + D  LEWPF 
Sbjct: 323 AERGEAMVRHSEGFYTGSCGYRLCVRVNINKSETRKVLYISLFVHFMQGKYDSSLEWPFR 382

Query: 287 GRISFVLVNQ-VYPELSQR---DTMMSNTNLKAFSKPATEICVRGFGYTEYAVLGDVIRN 342
           G I+  LV+Q + PEL Q+   + +++ +NL AF KP T    +GFGY E+A +  + + 
Sbjct: 383 GSITLSLVDQNIDPELKQKNITERLVAKSNLDAFKKPKTARNHKGFGYMEFASIESLEKE 442

Query: 343 G-FVKDDVLIIRVNI 356
           G F+KD+ ++I+V +
Sbjct: 443 GLFIKDNTILIKVEV 457


>UniRef50_Q9Y4K3 Cluster: TNF receptor-associated factor 6; n=18;
           Amniota|Rep: TNF receptor-associated factor 6 - Homo
           sapiens (Human)
          Length = 522

 Score =  111 bits (266), Expect = 4e-23
 Identities = 74/287 (25%), Positives = 132/287 (45%), Gaps = 29/287 (10%)

Query: 76  PEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTK 135
           P   IPC+F   GC E    ++ + +HL  +TQSHM +L  A   + +  D    +    
Sbjct: 236 PTAPIPCTFSTFGCHEKMQ-RNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRN 294

Query: 136 EQEAMALWDAPDKDGNQTSSPPLNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSA 195
            QE +   +                   L+R  ++ +  L  +   Q + ++ + + +  
Sbjct: 295 FQETIHQLEG-----------------RLVRQDHQ-IRELTAKMETQSMYVSELKRTIRT 336

Query: 196 FAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVR 255
                  +  E+  + C G Y+W+I NF   L    ++   +++SPGFYT   GY+ C+R
Sbjct: 337 LE----DKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMR 392

Query: 256 LNI----SPQNTHFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQ--RDTMMS 309
           L++    + +  ++ +L VH M+ E D  L WPF G I   +++Q    + Q   + M +
Sbjct: 393 LHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDA 452

Query: 310 NTNLKAFSKPATEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
              L AF +P      +GFGY  +  L  + +  F+KDD L++R  +
Sbjct: 453 KPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEV 499



 Score = 48.4 bits (110), Expect = 3e-04
 Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 4/65 (6%)

Query: 4   KGSLNSGH-CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHI 62
           K   ++GH CP+DN  + ++  +FPDN+ KREI    + CP   +GC  K+    L+ H 
Sbjct: 96  KSIRDAGHKCPVDN-EILLENQLFPDNFAKREILSLMVKCP--NEGCLHKMELRHLEDHQ 152

Query: 63  AVCEY 67
           A CE+
Sbjct: 153 AHCEF 157


>UniRef50_A2SVB5 Cluster: TRAF6; n=1; Chlamys farreri|Rep: TRAF6 -
           Chlamys farreri
          Length = 655

 Score =  105 bits (251), Expect = 2e-21
 Identities = 59/156 (37%), Positives = 94/156 (60%), Gaps = 12/156 (7%)

Query: 210 RYCMGNYVWRIDNF-KTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNI----SPQNTH 264
           R C G Y+W+I N+ K R +A   D    ++SP FY++  GY+ C+R+N+    S + TH
Sbjct: 498 RTCNGTYLWKIKNYSKFRREAEHGDT-TAIHSPPFYSNFYGYKLCIRVNLNGVDSARGTH 556

Query: 265 FFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQR----DTMMSNTNLKAFSKPA 320
             ++ +H M+ E DD LEWPF+GRI   +++Q  P   QR    +T++S  +L AF KP 
Sbjct: 557 L-SVFIHFMQGEYDDILEWPFSGRIVLTVLDQ-NPVCEQRHHVIETLVSKPHLAAFQKPV 614

Query: 321 TEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
           T    +GFGY E+  LG +  + ++++D L+I+  I
Sbjct: 615 TPRNHKGFGYMEFLPLGILDNSTYIQNDTLLIKAFI 650



 Score = 50.4 bits (115), Expect = 7e-05
 Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 12  CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYN 68
           CP+DN  L  +  IFPDN+ KREI    + CP    GC  +V    L  H+  CE++
Sbjct: 130 CPVDNAPLG-EGQIFPDNFAKREILALLVKCPNHKDGCDTQVVLKQLQKHLDSCEFS 185



 Score = 38.3 bits (85), Expect = 0.30
 Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 5/93 (5%)

Query: 76  PEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHM-NLLMNAYSEMKINNDMSNANMDT 134
           P+  I C FK  GCKE  + Q  M +H+ +  Q HM  +     S +++     +  +D+
Sbjct: 265 PKAVIDCEFKELGCKEMVERQ-AMAKHMQHSQQDHMQQMCTTIVSLVRLLKFKPDTLIDS 323

Query: 135 KEQEAMALWDAPDKDGNQTSSPPLNNTSALIRA 167
             Q +        ++G Q SS  LN  S L++A
Sbjct: 324 SRQSSSQ--SGQGEEGEQQSS-SLNALSGLLQA 353


>UniRef50_A7RI91 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 482

 Score =  101 bits (241), Expect = 4e-20
 Identities = 46/153 (30%), Positives = 90/153 (58%), Gaps = 6/153 (3%)

Query: 210 RYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQN---THFF 266
           R C G ++W++DNF+   +  +      ++SP FYTS  GY+ C+R+N++  +       
Sbjct: 328 RVCNGTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGLGEHV 387

Query: 267 ALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQR---DTMMSNTNLKAFSKPATEI 323
           +L +H+M+ + D  LEWPF GRI+  +++Q     S+R   +T+++  NL AF +P +  
Sbjct: 388 SLFIHMMQGDWDGILEWPFIGRITLSILDQSDQIDSRRPISETLVAKPNLLAFQRPTSPR 447

Query: 324 CVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
             +G+GY E+  +  +    ++K++ +++R+ I
Sbjct: 448 NHKGYGYVEFCPIDQLTEGQYIKNNSILVRIQI 480


>UniRef50_UPI0000E1EFBF Cluster: PREDICTED: TNF receptor-associated
           factor 5 isoform 2; n=1; Pan troglodytes|Rep: PREDICTED:
           TNF receptor-associated factor 5 isoform 2 - Pan
           troglodytes
          Length = 574

 Score = 97.1 bits (231), Expect = 6e-19
 Identities = 81/328 (24%), Positives = 152/328 (46%), Gaps = 34/328 (10%)

Query: 44  FSAKGCTVKVTPLDLDAHIAVCEYNQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHL 103
           F    C   +   ++D H+AVC          PE    C FK  GC  T D +  + +H 
Sbjct: 258 FCPNNCAKIILKTEVDEHLAVC----------PEAEQDCPFKHYGCAVT-DKRRNLQEHE 306

Query: 104 NNDTQSHMNLLMNAYSEMKINNDMSNANMDT-KEQEAMALWDAPDKDGNQTSSPPLNNTS 162
           ++  + HM L++    +++     S+ +     E +   L    ++  N+    PL    
Sbjct: 307 HSALREHMRLVLEKNVQLEEQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAV 366

Query: 163 ALIR---ALYE----RVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCM-G 214
             ++    L E    R+ VLE+   + D  I NI K      ++K ++  ++L   C  G
Sbjct: 367 DTVKQKITLLENNDQRLAVLEEETNKHDTHI-NIHKA----QLSKNEERFKLLEGTCYNG 421

Query: 215 NYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNI----SPQNTHFFALHV 270
             +W++ ++K +    +  H   ++S  FYTS  GYR C R  +    S + TH  +L+ 
Sbjct: 422 KLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGTH-LSLYF 480

Query: 271 HLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGF-- 328
            +M+ E D  L+WPF  R++ +L++Q   + +  +T   + N  +F +P  E+ +     
Sbjct: 481 VVMRGEFDSLLQWPFRQRVTLMLLDQ-SGKKNIMETFKPDPNSSSFKRPDGEMNIASGCP 539

Query: 329 GYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
            +  ++VL +  +N ++KDD L ++V +
Sbjct: 540 RFVAHSVLENA-KNAYIKDDTLFLKVAV 566


>UniRef50_A7SER6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 469

 Score = 94.3 bits (224), Expect = 4e-18
 Identities = 59/179 (32%), Positives = 95/179 (53%), Gaps = 14/179 (7%)

Query: 193 LSAFAVAKMKQNNEM--LLRYCM----GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTS 246
           +S  A+ + K+ N +  ++R+C        +WRID+F    D   +     L+SP FYTS
Sbjct: 286 VSELAIQQQKEINSLKEIVRHCKPYHDSKLLWRIDDFWEAFDEGKRKPGTELHSPVFYTS 345

Query: 247 PNGYRFCVRL----NISPQNTHFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELS 302
             GY+F V L    N S + TH  +L++ L+  E D  L WPF G+I+  L++Q   + +
Sbjct: 346 NYGYKFKVVLFPYGNGSGEGTHL-SLYIRLLPGEYDSLLPWPFEGQITLTLLDQSTDKRA 404

Query: 303 QRDTMMS---NTNLKAFSKPATEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNIKC 358
           +R    S   + N K+F +P+      GFGY ++     +   G+V+DDVL ++V I C
Sbjct: 405 KRHISQSFSPDPNWKSFQRPSKNSTSLGFGYPQFVSHRGLESIGYVRDDVLFLKVTIDC 463



 Score = 34.7 bits (76), Expect = 3.7
 Identities = 16/63 (25%), Positives = 29/63 (46%), Gaps = 1/63 (1%)

Query: 12  CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYNQPE 71
           CP+DN  +     ++ D+ T + I    + C +   GC  K     L  H+A C++   +
Sbjct: 54  CPVDNTAIDYS-QVYADDVTNQMIMSLTVICDYYQAGCKWKGQLRKLQGHLAECKFVSAD 112

Query: 72  TSS 74
            S+
Sbjct: 113 CSN 115


>UniRef50_Q32S42 Cluster: Tumor necrosis factor receptor associated
           factor 6; n=1; Euprymna scolopes|Rep: Tumor necrosis
           factor receptor associated factor 6 - Euprymna scolopes
          Length = 555

 Score = 93.1 bits (221), Expect = 1e-17
 Identities = 53/155 (34%), Positives = 85/155 (54%), Gaps = 10/155 (6%)

Query: 210 RYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQN---THFF 266
           R C G +VW+I N+  R          +++SP FY++  GY+ C+R N++  +       
Sbjct: 399 RLCNGLFVWKIKNYLQRRREAETGEMTVIHSPPFYSNFYGYKLCMRCNLNGVDFSVGRHL 458

Query: 267 ALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQR----DTMMSNTNLKAFSKPATE 322
           ++ +H M+ E DD L WPF G+I   +++Q  P   QR    +T++S   L AF +P T 
Sbjct: 459 SVFIHFMQGEWDDILSWPFRGKIVLSVLDQ-NPVADQRQHAVETLVSKPMLAAFQRPTTH 517

Query: 323 ICVRGFGYTEYAVLGDVIRNG-FVKDDVLIIRVNI 356
              +GFGY EY  L DV+ N  +V +D LI++  +
Sbjct: 518 RNHKGFGYMEYVPL-DVLDNSTYVVNDTLILKAQV 551



 Score = 50.4 bits (115), Expect = 7e-05
 Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 1/59 (1%)

Query: 10  GHCPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYN 68
           G CPIDN +L+    +FPDN+ KREI   ++ CP    GC   +    ++ H   C Y+
Sbjct: 53  GKCPIDNSDLT-DGQMFPDNFAKREILSMKVRCPNRKSGCNTCLELKHIEEHAESCPYH 110


>UniRef50_UPI00006A1D59 Cluster: TNF receptor-associated factor 2
           (Tumor necrosis factor type 2 receptor-associated
           protein 3).; n=2; Xenopus tropicalis|Rep: TNF
           receptor-associated factor 2 (Tumor necrosis factor type
           2 receptor-associated protein 3). - Xenopus tropicalis
          Length = 485

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 72/288 (25%), Positives = 132/288 (45%), Gaps = 22/288 (7%)

Query: 80  IPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAY-SEMKINNDMSNANM----DT 134
           +PC +   GC E  ++ D+  +H N     H+     A  +    NN    A M    DT
Sbjct: 200 VPCRYAAVGCTEMVEN-DKCLEHENKSLAEHLAKGSPAPPANAPPNNSAKVAEMLLKFDT 258

Query: 135 KEQEAMALWDAPDKDGNQT--SSPPLNNTSALIRALYERVVVLEQRNREQDIVIANISKQ 192
            +++     +       +   SS      +  +RA  E+V  L  + R+ +  +    K+
Sbjct: 259 LDKKNTTFENIVSVLNREVERSSHAAEELARQLRAAQEKVEALTTKVRQLERTLGQ--KE 316

Query: 193 LSAFAVAKMKQNNEMLLRYCMGNYVWRIDNF-KTRLDAMLKDHYKMLYSPGFYTSPNGYR 251
           L    +    Q +E  L    G ++W+I  F K R DA +      ++SP FYT+  GY+
Sbjct: 317 LIVAELETRMQESE--LSTYDGVFIWKISEFGKKRQDA-INGRCPAMFSPPFYTNKYGYK 373

Query: 252 FCVRLNI----SPQNTHFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTM 307
            C+R+ +    + +NTH  +L   +MK  ND  L WPFN +++ +L++Q   E    D  
Sbjct: 374 MCLRIYLNGDGTGRNTH-LSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNRE-HVIDAF 431

Query: 308 MSNTNLKAFSKPATEICVRGFGYTEYAVLGDVI-RNGFVKDDVLIIRV 354
             + +  +F +P +E+ +   G   +  +  +  +N +V+DD + ++V
Sbjct: 432 RPDVSSSSFQRPISEMNIAS-GCPLFCQVSKLEGKNSYVRDDTIFVKV 478


>UniRef50_A7RRA4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 422

 Score = 80.2 bits (189), Expect = 8e-14
 Identities = 86/365 (23%), Positives = 157/365 (43%), Gaps = 28/365 (7%)

Query: 12  CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIA----VCEY 67
           CP+DN+ L++   IFPDN   R+I    + CP    GC  + T  DL+ H+     + E 
Sbjct: 54  CPLDNLTLNVG-KIFPDNACHRQILSMDILCPHHGDGCEWQGTISDLEKHLERGCNLSEV 112

Query: 68  NQPETSSQP------EIHIP-CSFKPAGCKETFDSQ--DEMNQHLNNDTQSHMNLLMNAY 118
             P+           E H P CS +   C          +MN HL +     ++  +   
Sbjct: 113 RCPKDCGASVERGKLEGHYPECSRRLVNCTHCNKEVVFADMNVHLQSCASFPISCPLTCG 172

Query: 119 SEMKINNDMSNANMDTKEQEAMALWDAPDK--DGNQTSSPPLNNTSALIR-ALYERVVVL 175
           ++     D++   +     +   L   P +  +   T        +A ++ +L   V +L
Sbjct: 173 AK-----DLTKEALAVHLNQECPLLVIPCRFAEAGCTFKAKRQKMAAHVQESLTSHVAML 227

Query: 176 EQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRL-DAMLKDH 234
                EQ + I+   ++L         Q  E   R   G ++W+I  F  +L DA     
Sbjct: 228 CDLVCEQKLQISAQKERLLLQKEHIQLQIVECRSRCANGEFIWKIQCFSRKLMDAKTGRA 287

Query: 235 YKMLYSPGFYTSPNGYRFC--VRLN-ISPQNTHFFALHVHLMKTENDDCLEWPFNGRISF 291
            + + S  FYTSP+GY+ C  V LN I      + ++ + +   E D  L+WP   R +F
Sbjct: 288 SEPMISEAFYTSPHGYKMCAGVWLNGIGTGRGRYISVGLQVQSGEFDSILKWPLYPRYTF 347

Query: 292 VLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFGYTEYAVLGDVIRNGFVKDDVLI 351
            L++Q     ++RD +++    ++ S+P+ +  + G G   + +  +V    + KD+ + 
Sbjct: 348 TLLDQSEDTKTKRD-VVATFEPQSISRPSADRQL-GKGARRFVLQDEVCGTTYCKDNTIF 405

Query: 352 IRVNI 356
           I+ ++
Sbjct: 406 IKFSV 410


>UniRef50_Q12933 Cluster: TNF receptor-associated factor 2; n=41;
           Euteleostomi|Rep: TNF receptor-associated factor 2 -
           Homo sapiens (Human)
          Length = 501

 Score = 80.2 bits (189), Expect = 8e-14
 Identities = 77/331 (23%), Positives = 142/331 (42%), Gaps = 43/331 (12%)

Query: 43  PFSAKGCTVKVTPLD-LDAHIAVCEYNQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQ 101
           P +  GC  K  P +    H+  C           +  +PC F   GC ET + + +  +
Sbjct: 186 PLTCDGCGKKKIPREKFQDHVKTCG----------KCRVPCRFHAIGCLETVEGEKQQ-E 234

Query: 102 HLNNDTQSHMNLLMNAYSEMK-INNDMSNANMDTKEQEAMALWDAPDKDGNQTSSPPLNN 160
           H     + H+ +L+++  E K +  D S+A       E +   ++ +K      +    N
Sbjct: 235 HEVQWLREHLAMLLSSVLEAKPLLGDQSHAG-----SELLQRCESLEK-----KTATFEN 284

Query: 161 TSALIRALYERVVVL-----EQRNREQDIVIANISKQ--------LSAFAVAKMKQNN-E 206
              ++    ERV +       Q   +QD + A  SK         L   A+A ++Q   E
Sbjct: 285 IVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLE 344

Query: 207 MLLRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNT--- 263
           M      G ++W+I +F  +    +      ++SP FYTS  GY+ C+R+ ++   T   
Sbjct: 345 MEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRG 404

Query: 264 HFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEI 323
              +L   +MK  ND  L WPFN +++ +L++Q   E    D    +    +F +P  ++
Sbjct: 405 THLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNRE-HVIDAFRPDVTSSSFQRPVNDM 463

Query: 324 CVRGFGYTEYAVLGDV-IRNGFVKDDVLIIR 353
            +   G   +  +  +  +N +V+DD + I+
Sbjct: 464 NIAS-GCPLFCPVSKMEAKNSYVRDDAIFIK 493


>UniRef50_O00463 Cluster: TNF receptor-associated factor 5; n=20;
           Tetrapoda|Rep: TNF receptor-associated factor 5 - Homo
           sapiens (Human)
          Length = 557

 Score = 78.2 bits (184), Expect = 3e-13
 Identities = 52/194 (26%), Positives = 102/194 (52%), Gaps = 15/194 (7%)

Query: 170 ERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCM-GNYVWRIDNFKTRLD 228
           +R+ VLE+   + D  I NI K      ++K ++  ++L   C  G  +W++ ++K +  
Sbjct: 364 QRLAVLEEETNKHDTHI-NIHKA----QLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKR 418

Query: 229 AMLKDHYKMLYSPGFYTSPNGYRFCVRLNI----SPQNTHFFALHVHLMKTENDDCLEWP 284
             +  H   ++S  FYTS  GYR C R  +    S + +H  +L+  +M+ E D  L+WP
Sbjct: 419 EAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSH-LSLYFVVMRGEFDSLLQWP 477

Query: 285 FNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGF--GYTEYAVLGDVIRN 342
           F  R++ +L++Q   + +  +T   + N  +F +P  E+ +      +  ++VL +  +N
Sbjct: 478 FRQRVTLMLLDQ-SGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENA-KN 535

Query: 343 GFVKDDVLIIRVNI 356
            ++KDD L ++V +
Sbjct: 536 AYIKDDTLFLKVAV 549



 Score = 38.3 bits (85), Expect = 0.30
 Identities = 24/99 (24%), Positives = 43/99 (43%), Gaps = 11/99 (11%)

Query: 44  FSAKGCTVKVTPLDLDAHIAVCEYNQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHL 103
           F    C   +   ++D H+AVC          PE    C FK  GC  T D +  + QH 
Sbjct: 194 FCPNNCAKIILKTEVDEHLAVC----------PEAEQDCPFKHYGCAVT-DKRRNLQQHE 242

Query: 104 NNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMAL 142
           ++  + HM L++    +++      + +++ KE +   L
Sbjct: 243 HSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQL 281


>UniRef50_Q50IU9 Cluster: Tumour necrosis receptor-associated
           factor; n=1; Suberites domuncula|Rep: Tumour necrosis
           receptor-associated factor - Suberites domuncula
           (Sponge)
          Length = 544

 Score = 77.4 bits (182), Expect = 5e-13
 Identities = 46/144 (31%), Positives = 77/144 (53%), Gaps = 7/144 (4%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVR--LNISPQ--NTHFFALH 269
           G ++WRI N   R    +++    +YSP FYT  NGY+ C+R  LN   Q  NTH  +L 
Sbjct: 393 GAFLWRIPNIARRRRDAVEERITSIYSPPFYTGRNGYKMCIRAYLNGDGQGYNTH-LSLF 451

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFG 329
             +MK E D+ L+WPF  ++S +LV+Q + +     T        +F +P +++ V   G
Sbjct: 452 FVIMKGEFDNLLKWPFEHKVSMILVDQSHRK-HVVQTFKPTPESSSFQQPRSDMNVAS-G 509

Query: 330 YTEYAVLGDVIRNGFVKDDVLIIR 353
             +++ L     + + K+DV+ I+
Sbjct: 510 CPQFSKLSIFNDDSYCKEDVMYIK 533


>UniRef50_UPI0000E4A8D0 Cluster: PREDICTED: similar to
           CD40-associated protein, partial; n=6;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           CD40-associated protein, partial - Strongylocentrotus
           purpuratus
          Length = 530

 Score = 74.1 bits (174), Expect = 5e-12
 Identities = 48/148 (32%), Positives = 78/148 (52%), Gaps = 9/148 (6%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFFALH 269
           G +VW+I N+  +    +  + K +YSP FYTS  GY+ C R+ +      + TH  +L 
Sbjct: 374 GVFVWKIANYTEKKRDAMNTNVKSIYSPPFYTSQYGYKLCGRVFLMGDGVGKGTH-ISLF 432

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYP-ELSQRDTMMSNTNLKAFSKPATEICVRGF 328
           + +MK   D  L WPF  RI+F LVNQ  P   S  +    +    +F KP TE  + G 
Sbjct: 433 LTIMKGSFDAVLPWPFKERITFQLVNQDDPINKSIVEAFRPDPASSSFKKPTTEKNI-GA 491

Query: 329 GYTEYAVLGDV--IRNGFVKDDVLIIRV 354
           G   +A +  +   ++GFV+D+ + +++
Sbjct: 492 GCPLFAKIQIIEDPKSGFVRDNTVYLKI 519


>UniRef50_Q9BUZ4 Cluster: TNF receptor-associated factor 4; n=35;
           Chordata|Rep: TNF receptor-associated factor 4 - Homo
           sapiens (Human)
          Length = 470

 Score = 73.7 bits (173), Expect = 7e-12
 Identities = 49/158 (31%), Positives = 83/158 (52%), Gaps = 16/158 (10%)

Query: 214 GNYVWRIDNFKTRL-DAMLKDHYKMLYSPGFYTSPNGYRFCVRL----NISPQNTHFFAL 268
           G  +W+I ++  RL +A  K + +  +SP FYT   GY+  V      N S + TH  +L
Sbjct: 308 GVLIWKIGSYGRRLQEAKAKPNLEC-FSPAFYTHKYGYKLQVSAFLNGNGSGEGTHL-SL 365

Query: 269 HVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQ----RDTMMSNTNLKAFSKPAT--- 321
           ++ ++    D+ LEWPF  R++F L++Q  P L++     +T   + N K F KP T   
Sbjct: 366 YIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRG 425

Query: 322 --EICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNIK 357
             +    GFGY ++    D+ +  +V+DD + IR  ++
Sbjct: 426 SLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVE 463


>UniRef50_Q4S289 Cluster: Chromosome undetermined SCAF14764, whole
           genome shotgun sequence; n=4; Euteleostomi|Rep:
           Chromosome undetermined SCAF14764, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 624

 Score = 72.5 bits (170), Expect = 2e-11
 Identities = 44/166 (26%), Positives = 83/166 (50%), Gaps = 7/166 (4%)

Query: 193 LSAFAVAKMKQN-NEMLLRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYR 251
           L    VA+M+    EM      G +VWRI +F  +    +      ++SP FYTS  GY+
Sbjct: 453 LKDLTVAEMEGRLREMSATTFDGVFVWRISDFAKKRQDAIAGRAPAMFSPAFYTSKYGYK 512

Query: 252 FCVRLNISPQNT---HFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMM 308
            C+R+ ++   T      +L   +M+ ++D  L+WPFN +++ +L++Q   E    D   
Sbjct: 513 MCLRIYLNGDGTGRGSHLSLFFVVMRGQSDALLKWPFNQKVTLMLLDQSNRE-HIIDAFR 571

Query: 309 SNTNLKAFSKPATEICVRGFGYTEYAVLGDVI-RNGFVKDDVLIIR 353
            +    +F +P +E+ +   G   +  L  +  +N +++DD + I+
Sbjct: 572 PDVTSSSFQRPVSEMNIAS-GCPLFCPLSKLDGKNSYIRDDTIFIK 616


>UniRef50_Q13077 Cluster: TNF receptor-associated factor 1; n=11;
           Theria|Rep: TNF receptor-associated factor 1 - Homo
           sapiens (Human)
          Length = 416

 Score = 71.7 bits (168), Expect = 3e-11
 Identities = 51/190 (26%), Positives = 93/190 (48%), Gaps = 13/190 (6%)

Query: 170 ERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCM-GNYVWRIDNFKTRLD 228
           ER++ LEQR  E    +A   +     A+ K++Q+  ++      G ++W+I N   R  
Sbjct: 227 ERILSLEQRVVELQQTLAQKDQ-----ALGKLEQSLRLMEEASFDGTFLWKITNVTRRCH 281

Query: 229 AMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNT---HFFALHVHLMKTENDDCLEWPF 285
                    L+SP FYT+  GY+ C+RL ++   T      +L + +M+ E D  L WPF
Sbjct: 282 ESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPF 341

Query: 286 NGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFGYTEYAVLGDV--IRNG 343
             +++F+L++Q   E    D    + +  +F +P +E  V   G   +  L  +   ++ 
Sbjct: 342 RNKVTFMLLDQNNRE-HAIDAFRPDLSSASFQRPQSETNVAS-GCPLFFPLSKLQSPKHA 399

Query: 344 FVKDDVLIIR 353
           +VKDD + ++
Sbjct: 400 YVKDDTMFLK 409


>UniRef50_P39428 Cluster: TNF receptor-associated factor 1; n=7;
           Eutheria|Rep: TNF receptor-associated factor 1 - Mus
           musculus (Mouse)
          Length = 409

 Score = 70.5 bits (165), Expect = 6e-11
 Identities = 52/193 (26%), Positives = 92/193 (47%), Gaps = 20/193 (10%)

Query: 167 ALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNYVWRIDNFKTR 226
           +L +RVV L+Q   ++D V+  +   L     A              G ++W+I N   R
Sbjct: 224 SLEQRVVELQQTLAQKDQVLGKLEHSLRLMEEASFD-----------GTFLWKITNVTKR 272

Query: 227 LDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNI----SPQNTHFFALHVHLMKTENDDCLE 282
               +      L+SP FYT+  GY+ C+RL +    S + TH  +L + +M+ E D  L 
Sbjct: 273 CHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTH-LSLFIVIMRGEYDALLP 331

Query: 283 WPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFGYTEYAVLGDV--I 340
           WPF  +++F+L++Q   E    D    + +  +F +P +E  V   G   +  L  +   
Sbjct: 332 WPFRNKVTFMLLDQNNRE-HAIDAFRPDLSSASFQRPQSETNVAS-GCPLFFPLSKLQSP 389

Query: 341 RNGFVKDDVLIIR 353
           ++ +VKDD + ++
Sbjct: 390 KHAYVKDDTMFLK 402


>UniRef50_A7RGK7 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 411

 Score = 70.1 bits (164), Expect = 8e-11
 Identities = 50/172 (29%), Positives = 94/172 (54%), Gaps = 16/172 (9%)

Query: 197 AVAKMKQNNEMLLRYCM-GNYVWRIDNFKTRLD-AMLKDHYKMLYSPGFYTSPNGYRFCV 254
           A  K+++N    L  C  G ++W+I N+K + D A+       ++SP FYTS  GY+  +
Sbjct: 237 ACQKIRENESRSL--CTNGIFLWKISNYKHQYDQAVASPEELAIFSPPFYTSQYGYKLRL 294

Query: 255 RLNISPQN----THFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSN 310
           +  ++ ++    TH  +L++ +MK + D  LEWPF  +I+F L++Q   +  +   +  N
Sbjct: 295 KAYLNGRDRGKGTHL-SLYIIIMKGDYDALLEWPFKQKITFYLIDQSEKQNHRTHLLSPN 353

Query: 311 TNLK----AFSKPATEICVRGFGYTEYAVLGDVIRNG-FVKDDVLIIRVNIK 357
            +L      F++P  +  + G G   + V  +V+ +G +VKDDV+ I+  ++
Sbjct: 354 RSLPNIKVVFNRPTVKENL-GIGNPCF-VPNEVLESGEYVKDDVMFIKAVVE 403


>UniRef50_A5X2W4 Cluster: TNF receptor associated factor 1; n=2;
           Euteleostomi|Rep: TNF receptor associated factor 1 -
           Ctenopharyngodon idella (Grass carp)
          Length = 552

 Score = 68.9 bits (161), Expect = 2e-10
 Identities = 53/200 (26%), Positives = 98/200 (49%), Gaps = 20/200 (10%)

Query: 160 NTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNYVWR 219
           N+  +I+ L  ++   +QR   +DI I ++ + +SA          +  + Y  G ++WR
Sbjct: 360 NSQQIIQHLETKIAEQQQRLARKDIHITSLQQCISA----------QQDVSYD-GTFLWR 408

Query: 220 IDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFFALHVHLMKT 275
           + +   +L      H    YSP FYT+  G++ C+RL ++     + TH  +L   +MK 
Sbjct: 409 LCDVSQKLREAASGHKISQYSPAFYTARYGFKVCMRLYLNGDGVGKGTH-ISLFFVIMKG 467

Query: 276 ENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFGYTEYAV 335
           E D  L WPF  +++F L++Q   E    D    + +  +F +P +E+ V   G   +  
Sbjct: 468 EYDPILSWPFRHKVTFFLIDQNQRE-HVIDAFRPDLSSASFHRPVSEMNVAS-GCPLFFP 525

Query: 336 LGDV--IRNGFVKDDVLIIR 353
           LG +   ++ + KDD + I+
Sbjct: 526 LGKLRSPKHAYCKDDTIYIK 545


>UniRef50_UPI00006A045C Cluster: TNF receptor-associated factor 3
           (CD40 receptor-associated factor 1) (CRAF1)
           (CD40-binding protein) (CD40BP) (LMP1-associated
           protein) (LAP1) (CAP-1).; n=1; Xenopus tropicalis|Rep:
           TNF receptor-associated factor 3 (CD40
           receptor-associated factor 1) (CRAF1) (CD40-binding
           protein) (CD40BP) (LMP1-associated protein) (LAP1)
           (CAP-1). - Xenopus tropicalis
          Length = 459

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 44/146 (30%), Positives = 72/146 (49%), Gaps = 8/146 (5%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFFALH 269
           G  +W+I ++K R    +      LYS  FYT   GY+ C R+ ++     + TH  +L 
Sbjct: 313 GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTH-LSLF 371

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFG 329
             +M+ E D  L WPF  ++S +L++Q        D    + N  +F KP  E+ +   G
Sbjct: 372 FVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIAS-G 430

Query: 330 YTEYAVLGDVIRNG-FVKDDVLIIRV 354
              + V   V+ NG ++KDD + I+V
Sbjct: 431 CPVF-VAQTVLENGTYIKDDTIFIKV 455


>UniRef50_UPI00006A0459 Cluster: TNF receptor-associated factor 3
           (CD40 receptor-associated factor 1) (CRAF1)
           (CD40-binding protein) (CD40BP) (LMP1-associated
           protein) (LAP1) (CAP-1).; n=3; Xenopus tropicalis|Rep:
           TNF receptor-associated factor 3 (CD40
           receptor-associated factor 1) (CRAF1) (CD40-binding
           protein) (CD40BP) (LMP1-associated protein) (LAP1)
           (CAP-1). - Xenopus tropicalis
          Length = 526

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 44/146 (30%), Positives = 72/146 (49%), Gaps = 8/146 (5%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFFALH 269
           G  +W+I ++K R    +      LYS  FYT   GY+ C R+ ++     + TH  +L 
Sbjct: 374 GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTH-LSLF 432

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFG 329
             +M+ E D  L WPF  ++S +L++Q        D    + N  +F KP  E+ +   G
Sbjct: 433 FVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIAS-G 491

Query: 330 YTEYAVLGDVIRNG-FVKDDVLIIRV 354
              + V   V+ NG ++KDD + I+V
Sbjct: 492 CPVF-VAQTVLENGTYIKDDTIFIKV 516


>UniRef50_A7SBN4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 482

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 58/293 (19%), Positives = 121/293 (41%), Gaps = 12/293 (4%)

Query: 71  ETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNA 130
           E  S P    P   K  GC+ T +  ++    +    Q    + +N    M+I+ ++ N 
Sbjct: 185 EVHSTPFTREPRLEKGRGCENTLEVLEDHESRIKKLEQRGGGIGVNGLQSMRISENIDNE 244

Query: 131 NMDTKEQEAMALWDAPDKDGNQTSSPPLNNTSALIRALYERVVVLEQ-----RNREQDIV 185
            +    +  +A  +A   D         +    L R +    V L++     R  E+ + 
Sbjct: 245 AIGDVLRR-VANVEAKGADHEVLVVEAHSAVDELRREVGRLNVKLQESDDIIRRLERQLE 303

Query: 186 IANISKQLSAFAVAKMKQNNEMLLRYCMGNYV-WRIDNFKTRLDAMLKDHYKMLYSPGFY 244
           + +    L   A+A +++    L      + + W+I N   +            YSP F+
Sbjct: 304 LHDQGTGLRNLAIADLEERLNTLQGTTFDSVLLWKITNVANKRSEATSGRVTSFYSPCFF 363

Query: 245 TSPNGYRFCVRLNISPQ---NTHFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPEL 301
           T P+GY+ C R+ ++       H  +L   +M+ E D  L WPF  +++ +L++Q   E 
Sbjct: 364 TGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQDNVE- 422

Query: 302 SQRDTMMSNTNLKAFSKPATEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRV 354
              D    + +  +F +P  E+ +   G   +     + ++ +++DD + +++
Sbjct: 423 HVIDAFRPDPSSSSFQRPRAEMNIAS-GCPLFCSHEQLTQHAYIRDDTMFLKI 474


>UniRef50_Q706I7 Cluster: TNF-receptor-associated factor 1; n=1;
           Hydractinia echinata|Rep: TNF-receptor-associated factor
           1 - Hydractinia echinata (Snail fur) (Hermit crab
           hydroid)
          Length = 409

 Score = 68.1 bits (159), Expect = 3e-10
 Identities = 51/173 (29%), Positives = 89/173 (51%), Gaps = 14/173 (8%)

Query: 195 AFAVAKMKQNNEMLLRYCMGNY-VWRIDNFKTRLD-AMLKDHYKMLYSPGFYTSPNGYRF 252
           A AV K++ N    +  C   Y +W I  F+ + + A   D    ++S  FYTS  GY+ 
Sbjct: 237 AMAVVKVRVNESRSI--CTNGYFIWPIKRFRQQFELARNSDEEIAVFSQPFYTSQYGYKL 294

Query: 253 CVRLNISPQN----THFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYP---ELSQRD 305
            ++  ++ ++    TH  +L++ +MK E D  LEWPFN +I+F L++Q      ++ Q  
Sbjct: 295 RIKAYLNGRDRGKGTHL-SLYLIIMKGEFDALLEWPFNQKITFYLLDQGEDRKHKIHQLS 353

Query: 306 TMMSNTNLKA-FSKPATEICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNIK 357
              S  N++A F+KPA E  + G G   +     +    FVK+D + ++  ++
Sbjct: 354 PNRSLPNVRAVFNKPAAEENL-GIGNPSFVSHEAIDAGEFVKEDTIFMKCEVE 405


>UniRef50_UPI0000E4A50D Cluster: PREDICTED: similar to TRAF4
           protein; n=3; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to TRAF4 protein - Strongylocentrotus
           purpuratus
          Length = 542

 Score = 67.7 bits (158), Expect = 4e-10
 Identities = 39/153 (25%), Positives = 74/153 (48%), Gaps = 8/153 (5%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRL----NISPQNTHFFALH 269
           G  +WRI ++  +      +    L SP F+T   GY+  V +    N S +  H  +++
Sbjct: 360 GQLLWRITDYAEKFSKAKNEEEVELVSPPFFTGRYGYKLQVSIFPSGNGSGEGEHV-SVY 418

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQ---VYPELSQRDTMMSNTNLKAFSKPATEICVR 326
           + +   + D  L WPF   ISF L++Q       +  +++   +   K F +P+ ++ V 
Sbjct: 419 IRVTNGDFDSLLRWPFTFPISFTLLDQNEDPNKRMHIKESFTPDPTWKNFQRPSKDVHVL 478

Query: 327 GFGYTEYAVLGDVIRNGFVKDDVLIIRVNIKCV 359
           G+GY  +     +    ++KDDV+ +R +I+ V
Sbjct: 479 GYGYPTFVSHNFLKTRDYIKDDVMFLRASIEVV 511


>UniRef50_Q13114 Cluster: TNF receptor-associated factor 3; n=35;
           Euteleostomi|Rep: TNF receptor-associated factor 3 -
           Homo sapiens (Human)
          Length = 568

 Score = 67.7 bits (158), Expect = 4e-10
 Identities = 43/146 (29%), Positives = 72/146 (49%), Gaps = 8/146 (5%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFFALH 269
           G  +W+I ++K R    +      LYS  FYT   GY+ C R+ ++     + TH  +L 
Sbjct: 416 GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTH-LSLF 474

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFG 329
             +M+ E D  L WPF  +++ +L++Q        D    + N  +F KP  E+ +   G
Sbjct: 475 FVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIAS-G 533

Query: 330 YTEYAVLGDVIRNG-FVKDDVLIIRV 354
              + V   V+ NG ++KDD + I+V
Sbjct: 534 CPVF-VAQTVLENGTYIKDDTIFIKV 558


>UniRef50_A2TK67 Cluster: Tumor necrosis factor receptor-associated
           factor 2; n=1; Branchiostoma belcheri|Rep: Tumor
           necrosis factor receptor-associated factor 2 -
           Branchiostoma belcheri (Amphioxus)
          Length = 547

 Score = 66.5 bits (155), Expect = 1e-09
 Identities = 42/147 (28%), Positives = 73/147 (49%), Gaps = 9/147 (6%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFFALH 269
           G   W+I +F  +    +       YSP F+TS  GY+ C R+ ++     + TH  +L 
Sbjct: 397 GVLTWKIADFTRKRHDAITGKTASFYSPCFFTSRTGYKMCARVYLNGDGMGKGTH-VSLF 455

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFG 329
             +M+   D  L WPF  ++SF+LV+Q   E +  D    +    +F +P +++ +   G
Sbjct: 456 FVVMRGHYDGLLRWPFRQKVSFMLVDQNNRE-NVTDAFRPDPTSSSFQRPTSDMNIAS-G 513

Query: 330 YTEYAVLGDV--IRNGFVKDDVLIIRV 354
              +  L  +    +G+VKDD ++IRV
Sbjct: 514 CPLFVPLSQLESSSHGYVKDDTMLIRV 540



 Score = 41.5 bits (93), Expect = 0.033
 Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 12/114 (10%)

Query: 33  REIQEQRMNCPFS---AKGCTVK-VTPLDLDAHIAVCEYNQPETSSQPEIHIPCSFKPAG 88
           +E++  +  CP +      C+ K +T   L+ H        PET   P + I CSF+  G
Sbjct: 154 KELKAHKQTCPAAPVKCDWCSKKGLTRAQLEKH------QNPETGDCPSMKIACSFEHMG 207

Query: 89  CKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMAL 142
           CK+  + + +  +HL    Q+H++ + N Y      N   +     + +E+M +
Sbjct: 208 CKDRMEKR-QFPEHLKKTVQNHLS-MTNTYVICLATNFEQHRQKVEESRESMQI 259


>UniRef50_UPI00015A66C8 Cluster: TNF receptor-associated factor 5
           (RING finger protein 84).; n=1; Danio rerio|Rep: TNF
           receptor-associated factor 5 (RING finger protein 84). -
           Danio rerio
          Length = 455

 Score = 64.9 bits (151), Expect = 3e-09
 Identities = 65/289 (22%), Positives = 129/289 (44%), Gaps = 22/289 (7%)

Query: 77  EIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKE 136
           E+   C +K  GC    D + ++  H N +  +H+ L++    E  + +    + + T  
Sbjct: 180 EVETDCVYKNYGCTVR-DKRGKVQVHENTEFSAHVRLVLEKLCEQTLCSLTMQSRVSTFS 238

Query: 137 QEAMALWDAPDKDGN-QTSSPPLNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSA 195
            +  ++ +   +  + Q     L    + ++    R+       R+Q  V  ++ + L A
Sbjct: 239 CDRRSVEEQRVRICSVQRELRDLRVLGSELKEELPRLQASLDSLRQQVAVTESLREHLVA 298

Query: 196 FAVAKMKQNNEMLLRYCM-GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCV 254
                +KQ++  L      G  +W++ ++  R     K+    L S  FYTS +GY+  V
Sbjct: 299 -----LKQHSTFLESSSYDGKLIWKVRDYWHR-----KESGAALSSSPFYTSRSGYKLSV 348

Query: 255 RLNI----SPQNTHFFALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSN 310
           R  +    S + +H  +L++ +M+ + D  L WPF   I+  L++Q         T + +
Sbjct: 349 RAYLGGDGSGRGSHM-SLYITIMRGDFDSFLPWPFRQNITLTLLDQSGTRNHMSHTFIPD 407

Query: 311 TNLKAFSKPATEICVRGFGYTEYAVLGDV--IRNG-FVKDDVLIIRVNI 356
            N  +F +P ++  V   G+T +    D+   RN  FV+D+ L I+V +
Sbjct: 408 VNSDSFHRPTSDANV-ATGFTRFISHCDLENPRNAVFVRDETLFIKVKV 455


>UniRef50_Q4TBW0 Cluster: Chromosome undetermined SCAF7089, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7089,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 607

 Score = 64.5 bits (150), Expect = 4e-09
 Identities = 38/146 (26%), Positives = 70/146 (47%), Gaps = 6/146 (4%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFFALH 269
           G  +W+I ++K R    +      LYS  FYT   GY+ C R+ ++     + TH  +L 
Sbjct: 431 GTLIWKIRDYKRRKQEAVAAKTLSLYSQPFYTGYFGYKMCARIYLNGDGMGKGTH-LSLF 489

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFG 329
             +M+ E D  L WPF  +++ +L++Q   +    D    + N  +F +P  E+ +   G
Sbjct: 490 FVVMRGEYDALLPWPFKQKVTLMLMDQGPLKKHLGDAFKPDPNSSSFRRPVVEMNIAS-G 548

Query: 330 YTEYAVLGDVIRNGFVKDDVLIIRVN 355
              +     +    ++KDD + I+V+
Sbjct: 549 CPLFVSQSVLETGSYIKDDTIFIKVS 574


>UniRef50_UPI00005845EF Cluster: PREDICTED: similar to zinc finger
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to zinc finger protein -
           Strongylocentrotus purpuratus
          Length = 425

 Score = 64.1 bits (149), Expect = 5e-09
 Identities = 39/149 (26%), Positives = 71/149 (47%), Gaps = 10/149 (6%)

Query: 217 VWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQN---THFFALHVHLM 273
           VW+ID +  R+    +     ++SP F TS +GYR  V   ++      +HF ++ V + 
Sbjct: 270 VWKIDKYAERMQEAKQGKKVTIFSPPFLTSRHGYRLSVSCCLNGDGKAKSHFMSIFVCIN 329

Query: 274 KTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMS------NTNLKAFSKPATEICVRG 327
           + E D  L WPF+ RI+F L++Q     ++R+   +        N     +P  E     
Sbjct: 330 RGEYDALLPWPFSHRITFTLIDQCQDPTARRNISYNIKPNPCKENKAFLGRPLGERNA-S 388

Query: 328 FGYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
           FG  ++  L  +    +++DD + I+V +
Sbjct: 389 FGTQKFVPLNMIKTLDYIRDDTMFIKVQV 417


>UniRef50_A7STV3 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 464

 Score = 64.1 bits (149), Expect = 5e-09
 Identities = 40/152 (26%), Positives = 75/152 (49%), Gaps = 12/152 (7%)

Query: 217 VWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFFALHVHL 272
           +WRI+++  +L      + + L+SP F TS +GYR C  + ++     + TH  ++ V +
Sbjct: 309 IWRIEDYTRKLKEAKAGNAETLFSPTFTTSKHGYRLCASVCLNGDGKGKGTH-MSVFVSV 367

Query: 273 MKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMS------NTNLKAFSKPATEICVR 326
           +K   D  L+WPF+ R++F L+NQ      ++    S        N     +P  E    
Sbjct: 368 LKGAFDALLKWPFHYRVTFFLLNQHENPEERKHVKFSIKPNPIPDNEPFLGRPRLEKNA- 426

Query: 327 GFGYTEYAVLGDVIRNGFVKDDVLIIRVNIKC 358
            FG  ++    ++    F+KDD + ++V++ C
Sbjct: 427 SFGGAKFIKHEEIESGNFIKDDTVFLKVSVDC 458


>UniRef50_UPI00015A639D Cluster: hypothetical protein LOC445119;
           n=1; Danio rerio|Rep: hypothetical protein LOC445119 -
           Danio rerio
          Length = 466

 Score = 63.7 bits (148), Expect = 7e-09
 Identities = 40/145 (27%), Positives = 72/145 (49%), Gaps = 8/145 (5%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFFALH 269
           G  +W+I ++K R    +      LYS  FYT   GY+ C R+ ++     + TH  +L 
Sbjct: 314 GTLIWKIRDYKRRKQEAVVSKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTH-LSLF 372

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFG 329
             +M+ E D  L+WPF  +++ +L++Q        D    + +  +F +P  E+ +   G
Sbjct: 373 FVVMRGEYDALLQWPFKQKVTLMLMDQGPARKHLGDAFKPDPSSSSFRRPTGEMNIAS-G 431

Query: 330 YTEYAVLGDVIRNG-FVKDDVLIIR 353
              + V   V+ NG ++KDD + I+
Sbjct: 432 CPLF-VAQTVLENGTYIKDDTIFIK 455


>UniRef50_A7SX78 Cluster: Predicted protein; n=5; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 399

 Score = 63.7 bits (148), Expect = 7e-09
 Identities = 47/155 (30%), Positives = 81/155 (52%), Gaps = 22/155 (14%)

Query: 213 MGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVR--LNISPQN--THFFAL 268
           +G +VWRI ++K        D Y+ +YSP FYTS  GY+  ++  L+ +P N  TH + L
Sbjct: 257 VGTFVWRICDYK--------DLYEEIYSPSFYTSKYGYKVQLKAYLHTNPFNGETHLW-L 307

Query: 269 HVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTN------LKAFSKPATE 322
           +  +M  E D  LEWPF  +I+  +++Q   +  + +T++ N +       K F +P   
Sbjct: 308 YACIMVGEYDALLEWPFRRKITLYVIDQ--SDQRKHETLLINPDDVLPDRKKCFHRPIMG 365

Query: 323 ICVRGFGYTEYAVLGDVIRNGFVKDDVLIIRVNIK 357
             V G+  T    L ++   GF+ D V+ I+  ++
Sbjct: 366 NNV-GYCLTRSLSLEELTSGGFIADGVMFIKAVVE 399


>UniRef50_UPI0000ECA75E Cluster: TNF receptor-associated factor 1
           (Epstein-Barr virus-induced protein 6).; n=1; Gallus
           gallus|Rep: TNF receptor-associated factor 1
           (Epstein-Barr virus-induced protein 6). - Gallus gallus
          Length = 504

 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 72/329 (21%), Positives = 140/329 (42%), Gaps = 20/329 (6%)

Query: 37  EQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYNQPETSSQPEIHIPCSFKPAGCKETFDSQ 96
           E + +CP   K C  +   + +     + ++ +  + S       C F   GC     S+
Sbjct: 176 EYQPHCPRKPKVCRSEPAVILMTGTFMLSDHLRASSVSMDG----CRFSEVGCSFG-GSK 230

Query: 97  DEMNQHLNNDTQSHMNLLMNAYSEMKINN-DMSNANMDTKEQEAMALWDAPDKDGNQTSS 155
           +++ +H      +HM LL+    ++K N   +S A      Q  + L +      N  + 
Sbjct: 231 EKIKEHEKAAVGTHMLLLLQYIKQLKANLCTVSKAANGFISQTELNLENKLHVFENIVAV 290

Query: 156 PPLN-NTSALIRALYERVVVLEQRN-REQDIVIANISKQLSAFAVAKMKQNNEMLLRYCM 213
                 TS L    + R   L+Q   R  ++ IA +   L+       + +  ++     
Sbjct: 291 LNKEVETSNLEITAFRRQSELDQNVIRGLELKIAELHHCLTQKDAGLSRLHKSLVFSEQT 350

Query: 214 ---GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFF 266
              G ++W+I +   +L   +      LYSP FYT+  GY+ C+R+ ++     + TH  
Sbjct: 351 SYDGVFLWKITDVNQKLQDSVTGRVVSLYSPAFYTAKYGYKVCLRIYLNGDGMGKGTH-V 409

Query: 267 ALHVHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVR 326
           +L   +MK + D  L WPF  +++F+L++Q   E    D    +    +F +P  ++ V 
Sbjct: 410 SLFFVVMKGDYDALLPWPFRHKVTFMLLDQNNRE-HIIDAFRPDLASASFQRPVNDMNVA 468

Query: 327 GFGYTEYAVLGDV--IRNGFVKDDVLIIR 353
             G   +  L  +   ++ +VK+D L ++
Sbjct: 469 S-GCPTFLPLTKLQSPKHAYVKEDTLFLK 496


>UniRef50_A7S6K0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 382

 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 47/196 (23%), Positives = 95/196 (48%), Gaps = 16/196 (8%)

Query: 171 RVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRL--D 228
           +V  +E     QD + +++   ++   + +++Q  E +     G ++W+I N+ T+L   
Sbjct: 190 KVKRIEMEKHLQDSMASHLD--MAHIRIRELEQRQEKICTN--GKFLWKISNY-TQLFQQ 244

Query: 229 AMLKDHYKMLYSPGFYTSPNGYRFCVRLNISP----QNTHFFALHVHLMKTENDDCLEWP 284
           +  K   + L SP FYT   GY+      ++     + TH  +L+V +MK + D  L WP
Sbjct: 245 SATKKEKEKLCSPPFYTGQYGYKLRAEAFLNGLGQGKGTHL-SLYVVIMKGDYDSVLPWP 303

Query: 285 FNGRISFVLVNQVYPELSQRD---TMMSNTNLKAFSKPATEICVRGFGYTEYAVLGDVIR 341
           F  R+ F+L++Q     S+++    +  + N   F +P  +    GFG  ++     +  
Sbjct: 304 FQQRVDFILIDQDDDFTSRQNKTWRLTCDRNSDYFGRP-NKAKSLGFGCPKFVSQETLKS 362

Query: 342 NGFVKDDVLIIRVNIK 357
             FV+D+ + I + ++
Sbjct: 363 RNFVRDNTVFIMIEVE 378


>UniRef50_A7RG36 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 531

 Score = 61.3 bits (142), Expect = 4e-08
 Identities = 36/146 (24%), Positives = 66/146 (45%), Gaps = 5/146 (3%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNT---HFFALHV 270
           G Y+W+ID +  R    +      +YSP FY    GY+ C R+  +          +L  
Sbjct: 378 GTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFF 437

Query: 271 HLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFGY 330
            LM+ E D  L WPF  +++F L++Q        DT   +    +F +P + + +   G 
Sbjct: 438 VLMRGEFDALLPWPFRQKVTFKLLDQDRVH-DIGDTFRPDPTSSSFKRPTSNMNIAS-GC 495

Query: 331 TEYAVLGDVIRNGFVKDDVLIIRVNI 356
             +    ++    +V+DD + I++ +
Sbjct: 496 PLFISHTNLQTRAYVRDDTMFIKIAV 521



 Score = 33.9 bits (74), Expect = 6.5
 Identities = 19/69 (27%), Positives = 36/69 (52%), Gaps = 3/69 (4%)

Query: 71  ETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNA-YSEMKINNDMSN 129
           +T+   +  +PCSF   GC     +++ +  H  +    H+NLL+ A  +E K  ++M+ 
Sbjct: 185 QTNICEQAELPCSFAKHGC-HFKGTREALETHFRDQASVHVNLLLTATQNEEKARSEMA- 242

Query: 130 ANMDTKEQE 138
           A +   E+E
Sbjct: 243 AKLSQMEKE 251


>UniRef50_A2TK68 Cluster: Tumor necrosis factor receptor-associated
           factor 3; n=1; Branchiostoma belcheri|Rep: Tumor
           necrosis factor receptor-associated factor 3 -
           Branchiostoma belcheri (Amphioxus)
          Length = 565

 Score = 61.3 bits (142), Expect = 4e-08
 Identities = 36/149 (24%), Positives = 69/149 (46%), Gaps = 6/149 (4%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNIS----PQNTHFFALH 269
           G  +W+I ++  R    +      LYS  FYTS  GY+ C R+ ++     + TH  +L 
Sbjct: 413 GTLLWKIKDYTRRKHDAVTGRTLSLYSQPFYTSQFGYKMCARVYLNGDGMGKGTH-MSLF 471

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFG 329
             +M+ E D  L WPF  +++ +L++Q        DT   +    +F +P +++ +   G
Sbjct: 472 FVVMRGEYDALLPWPFRQKVTLMLLDQDQGRRHLSDTFRPDPTSSSFKRPTSDMNIAS-G 530

Query: 330 YTEYAVLGDVIRNGFVKDDVLIIRVNIKC 358
              +          ++ +D + I+V + C
Sbjct: 531 CPLFVSQSVAESKTYLNEDTIFIKVIVDC 559



 Score = 48.4 bits (110), Expect = 3e-04
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 12/95 (12%)

Query: 12  CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYNQPE 71
           CPID   L    ++FPD +  REI   ++ C F   GC   +   +L+AH+  CEY    
Sbjct: 76  CPIDGEELRQD-EVFPDLFCIREILMSKVYCRFKKNGCQEILLLRNLEAHVNECEY---- 130

Query: 72  TSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNND 106
                   I C FK AGC  T   +  +  HL+++
Sbjct: 131 ------AIIDCIFKEAGCIITLQRR-HLPHHLDSE 158


>UniRef50_UPI000056A9B8 Cluster: TNF receptor-associated factor 1
           (Epstein-Barr virus-induced protein 6).; n=1; Danio
           rerio|Rep: TNF receptor-associated factor 1
           (Epstein-Barr virus-induced protein 6). - Danio rerio
          Length = 537

 Score = 60.5 bits (140), Expect = 7e-08
 Identities = 49/199 (24%), Positives = 93/199 (46%), Gaps = 18/199 (9%)

Query: 160 NTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNYVWR 219
           N+  +I+ L   V  L+QR   +DI+I+++ + +SA          +  + Y  G + WR
Sbjct: 345 NSQQIIQHLEATVAELQQRLVRKDILISSLQQSISA----------QQDVSYD-GTFYWR 393

Query: 220 IDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNT---HFFALHVHLMKTE 276
           + +   +            YSP FYT+  G++ C+RL ++          +L   +MK E
Sbjct: 394 VCDVSQKQREAANSQKISQYSPAFYTARYGFKVCLRLYLNGDGAGKGSHISLFFVIMKGE 453

Query: 277 NDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFGYTEYAVL 336
            D  L WPF  +++F L++Q   E    D    + +  +F +P +++ V   G   +  L
Sbjct: 454 YDPILSWPFKHKVTFFLLDQNQRE-HVIDAFRPDLSSMSFHQPVSDMNVAS-GCPLFFPL 511

Query: 337 GDV--IRNGFVKDDVLIIR 353
             +   ++ + KDD + I+
Sbjct: 512 KKLRSPKHAYCKDDTIYIK 530


>UniRef50_UPI0000E4656D Cluster: PREDICTED: similar to TRAFamn; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           TRAFamn - Strongylocentrotus purpuratus
          Length = 440

 Score = 59.7 bits (138), Expect = 1e-07
 Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 6/145 (4%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISP----QNTHFFALH 269
           G  +W+I  F  R           LYS  FYTS  GY+ C R+ ++     + TH     
Sbjct: 288 GTLIWKIKEFARRKRDADNGKTLSLYSQPFYTSRFGYKMCARIYLNGDGIGKGTHVSLFF 347

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFG 329
           V +MK + D  L WPF+ +++ +L++Q        D+   +    +F +P+T + +   G
Sbjct: 348 V-VMKGDYDALLPWPFSQKVTLMLLDQETGRRHLSDSFRPDPTSTSFQRPSTNMNIAS-G 405

Query: 330 YTEYAVLGDVIRNGFVKDDVLIIRV 354
              +     +    +VK+D + I+V
Sbjct: 406 CPLFVSQSVLKDPAYVKEDTIFIKV 430


>UniRef50_Q9XYR0 Cluster: CG3048-PA, isoform A; n=8;
           Endopterygota|Rep: CG3048-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 486

 Score = 58.8 bits (136), Expect = 2e-07
 Identities = 39/150 (26%), Positives = 76/150 (50%), Gaps = 9/150 (6%)

Query: 214 GNYVWRIDNFKTRL-DAMLKDHYKMLYSPGFYTSPNGYRFCVRL----NISPQNTHFFAL 268
           G  +W+I ++  ++ +A  KD  +++ SP FYTS  GY+    +    N   +NTH  ++
Sbjct: 331 GTLLWKITDWSAKMAEARGKDGLELV-SPPFYTSQYGYKLQASMFLNGNGPGENTHV-SV 388

Query: 269 HVHLMKTENDDCLEWPFNGRISFVLVNQ--VYPELSQRDTMMSNTNLKAFSKPATEICVR 326
           ++ ++  E D  L+WPF+  I+F L  Q     +    ++ + +   + F +P+ E    
Sbjct: 389 YIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQL 448

Query: 327 GFGYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
           GFG+  +     +    F+K D + +RV +
Sbjct: 449 GFGFPRFISHELLHSRPFIKGDTVFLRVKV 478


>UniRef50_UPI0000F2106A Cluster: PREDICTED: similar to TRAF5; n=1;
           Danio rerio|Rep: PREDICTED: similar to TRAF5 - Danio
           rerio
          Length = 231

 Score = 58.4 bits (135), Expect = 3e-07
 Identities = 42/150 (28%), Positives = 75/150 (50%), Gaps = 14/150 (9%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNI----SPQNTHFFALH 269
           G  +W++ ++  R     K+    L S  FYTS +GY+  VR  +    S + +H  +L+
Sbjct: 81  GKLIWKVRDYWHR-----KESGAALSSSPFYTSRSGYKLSVRAYLGGDGSGRGSHM-SLY 134

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFG 329
           + +M+ + D  L WPF   I+  L++Q         T + + N  +F +P ++  V   G
Sbjct: 135 ITIMRGDFDSFLPWPFRQNITLTLLDQSGTRNHMSHTFIPDVNSDSFHRPTSDANV-ATG 193

Query: 330 YTEYAVLGDV--IRNG-FVKDDVLIIRVNI 356
           +T +    D+   RN  FV+D+ L I+V +
Sbjct: 194 FTRFISHCDLENPRNAVFVRDETLFIKVKV 223


>UniRef50_A7SM27 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 524

 Score = 56.8 bits (131), Expect = 8e-07
 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRL---NISPQNTHFFALHV 270
           G ++W+ID F  R       +   +YS  FYT   GY+ C RL          ++ ++ +
Sbjct: 380 GTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFI 439

Query: 271 HLMKTENDDCLEWPFNGRISFVLVNQ 296
            LM+ E D  L WPF   I+  L++Q
Sbjct: 440 ALMRGEYDSILPWPFQETITITLIDQ 465


>UniRef50_Q4RF33 Cluster: Chromosome 14 SCAF15120, whole genome
           shotgun sequence; n=4; Euteleostomi|Rep: Chromosome 14
           SCAF15120, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 932

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 47/164 (28%), Positives = 79/164 (48%), Gaps = 24/164 (14%)

Query: 215 NYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRL----NISPQNTHFFALHV 270
           N VWRI NF   ++   +  + +L+SP FY SP GY + VRL    N +    ++  L+ 
Sbjct: 449 NAVWRIQNFSKIMETATR--HTVLHSPRFY-SPEGYGYGVRLVPLSNYTDYTGNYTGLYF 505

Query: 271 HLMKTENDDCLEWPFNGRISFVLVNQVYPELSQR-------DTMMSNTNLKAFSKPATEI 323
           HL   END  L+WP   R + ++V    P++  R        T M  ++ K      +++
Sbjct: 506 HLASGENDAVLQWPAINRQATLVVMDQDPDIKLRMSTARSLTTDMRTSDGKLLWDDPSKV 565

Query: 324 --------CVRG--FGYTEYAVLGDVIRNGFVKDDVLIIRVNIK 357
                   C RG  +G+  +    D+ R  ++K+D LII ++ +
Sbjct: 566 GTYDPSCDCHRGVSWGWRNFVKHFDLRRRNYLKNDDLIIFIDFE 609


>UniRef50_A7RJK8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 488

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 74/322 (22%), Positives = 127/322 (39%), Gaps = 48/322 (14%)

Query: 76  PEIHIPCSFKPAGCKETFDSQDEM-NQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDT 134
           P   +PC F   GC  TF  ++   ++H  +  Q+H+++      + K      +  +D 
Sbjct: 173 PLAFLPCRFSEIGC--TFKGRESARDEHCESAVQTHLHIACETIRDNKEQISDLHKELDK 230

Query: 135 KEQEAMALWDAPDKDGN---QTSSPPLNNTSALIRALYERVVVLEQRNREQDIVIANISK 191
             QE         K+ N   +     + +    I AL +   +      E    +  + K
Sbjct: 231 VRQELQTKSCDHMKEVNAIREKHDEAIRDNKGQIEALSKEHGIASNTIHENKEQLDTLKK 290

Query: 192 QLSAFAVAKMKQNNEMLLR--------YCMGNYVWRIDNFKTRLDAMLK----------- 232
           +L   A   +++N + + +        Y  G +VWRI N+K +    +            
Sbjct: 291 ELG-IASETIRKNRDQIAKLSTACKTQYTDGTFVWRICNYKDKYKKAVAFATNQEVKGGN 349

Query: 233 ----DHYKM----LYSPGFYTSPNGYRFCVRLNISP------QNTHFFALHVHLMKTEND 278
               D   M    + S  FYTS  GY+  +RL   P      + TH  +L + +MK E D
Sbjct: 350 SDSDDDISMAGDIMVSLPFYTSRYGYK--MRLKAYPNGYGDGKGTHL-SLSIRIMKGEYD 406

Query: 279 DCLEWPFNGRISFVLVNQVYPELSQRDTMMSN----TNLKAFSKPATEICVRGFGYTEYA 334
             LEWPF  +I+  L+NQ     S+   +  +         F +P     V G GY+ + 
Sbjct: 407 AILEWPFRRKITLSLINQSEQWRSETVEIYPDDATPDKKHKFERPIENENV-GCGYSCFI 465

Query: 335 VLGDVIRNGFVKDDVLIIRVNI 356
              ++    ++KDDV+ I   I
Sbjct: 466 SHMELNSGDYIKDDVIFIEAVI 487


>UniRef50_A7S4Z7 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 468

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 43/148 (29%), Positives = 67/148 (45%), Gaps = 9/148 (6%)

Query: 216 YVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRL----NISPQNTHFFALHVH 271
           +VWRI +F   L          L S  F+T  NGY+    L     +S +NTH  A  V 
Sbjct: 320 FVWRIPDFADSLRQAKLGLKVRLDSEPFFTEKNGYKLRATLYPNGTMSGKNTHISAF-VS 378

Query: 272 LMKTENDDCLEWPFNGRISFVLVNQVYPELSQRD---TMMSNTNLKAFSKPATEICVRGF 328
           + + E D  L WPF   I   L++Q    L +R+   T++ N +L+ F +P T +   G 
Sbjct: 379 INRGEYDGILAWPFTRVIKITLLDQKENVLQRRNVEKTIIPNPSLENFHRPKT-VSNNGR 437

Query: 329 GYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
           G   +     +    +V D  L ++V +
Sbjct: 438 GSATFVSHEKLWTENYVVDGTLFMQVEV 465



 Score = 43.6 bits (98), Expect = 0.008
 Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 3/65 (4%)

Query: 12  CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYNQPE 71
           CP+D   L +K D+F D   +R I    + CP   KGC  +    DL+AH   C+Y +  
Sbjct: 61  CPMDREPLDLKKDVFLDKAAERTILSFLVKCP--CKGCKWEAELRDLEAHARNCDY-ELV 117

Query: 72  TSSQP 76
           T S P
Sbjct: 118 TCSNP 122



 Score = 36.7 bits (81), Expect = 0.93
 Identities = 14/37 (37%), Positives = 25/37 (67%), Gaps = 1/37 (2%)

Query: 80  IPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMN 116
           +PC+F+  GC+    ++  M+QHL+ + QSH+N+  N
Sbjct: 255 VPCAFRDFGCEVEIQNR-LMDQHLDTNIQSHLNMTCN 290


>UniRef50_Q4KS49 Cluster: Tumor necrosis factor type 2 receptor
           associated protein; n=3; Infectious spleen and kidney
           necrosis virus|Rep: Tumor necrosis factor type 2
           receptor associated protein - Orange-spotted grouper
           iridovirus
          Length = 206

 Score = 53.6 bits (123), Expect = 8e-06
 Identities = 37/124 (29%), Positives = 63/124 (50%), Gaps = 7/124 (5%)

Query: 237 MLYSPGFYTSPNGYRFCVRL----NISPQNTHFFALHVHLMKTENDDCLEWPFNGRISFV 292
           M+ SP FYT  NGY  CVR+    + S   TH  +++ +++K   DD LEWPF+  ++  
Sbjct: 83  MILSPVFYTHRNGYAMCVRMYPKGDGSGTGTH-LSMYFNVLKGPVDDNLEWPFSKHVTVS 141

Query: 293 LVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFGYTEYAVLGDVIRNGFVKDDVLII 352
           LV Q         ++ SN +  +F+KP   +     G+  +  L  V    + K+  L +
Sbjct: 142 LVGQEPGVPDIVHSLRSNFDSVSFNKPVGVVPNIPIGWPTFCPLTCVPM--YTKNGQLCV 199

Query: 353 RVNI 356
           +V++
Sbjct: 200 KVHV 203


>UniRef50_Q16819 Cluster: Meprin A subunit alpha precursor; n=38;
           Euteleostomi|Rep: Meprin A subunit alpha precursor -
           Homo sapiens (Human)
          Length = 746

 Score = 48.4 bits (110), Expect = 3e-04
 Identities = 35/106 (33%), Positives = 49/106 (46%), Gaps = 5/106 (4%)

Query: 217 VWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNI-SPQNTHFFALHVHLMKT 275
           VW + NF   L+   K     L SP FY S  GY F V L   S +++ +  L  H+   
Sbjct: 435 VWTVRNFSQVLENTSKGD--KLQSPRFYNS-EGYGFGVTLYPNSRESSGYLRLAFHVCSG 491

Query: 276 ENDDCLEWPFNGRISFVLVNQVYPELSQR-DTMMSNTNLKAFSKPA 320
           END  LEWP   R   + +    P++  R  + M  T  K+ + PA
Sbjct: 492 ENDAILEWPVENRQVIITILDQEPDVRNRMSSSMVFTTSKSHTSPA 537


>UniRef50_A7SJA2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 123

 Score = 46.4 bits (105), Expect = 0.001
 Identities = 29/101 (28%), Positives = 52/101 (51%), Gaps = 10/101 (9%)

Query: 216 YVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISP----QNTHFFALHVH 271
           +VWRI N+  + +       + + S  FYTS  GY+  ++ +++     + TH  +L V 
Sbjct: 17  FVWRIRNYNDQYEKK-----QTISSRLFYTSRYGYKMRLKSHLNGNGDGKGTHL-SLFVQ 70

Query: 272 LMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTN 312
           + K E D  LEWPF  +I+  L++Q+  +    D  +  T+
Sbjct: 71  ITKGEYDALLEWPFKRKITLYLIDQIDQQRHMYDKPIQGTD 111


>UniRef50_Q70AC9 Cluster: TNF-receptor associated factor 6; n=1;
          Sus scrofa|Rep: TNF-receptor associated factor 6 - Sus
          scrofa (Pig)
          Length = 276

 Score = 44.4 bits (100), Expect = 0.005
 Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)

Query: 4  KGSLNSGH-CPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHI 62
          K   ++GH CP+DN  + ++  +FPDN+ KREI    + CP    GC  K+     + H 
Sbjct: 8  KSIRDAGHKCPVDN-EILLENQLFPDNFAKREILSXTVKCP--NVGCLHKMELRHXEDHQ 64

Query: 63 AVCE 66
          A CE
Sbjct: 65 AHCE 68


>UniRef50_Q16820 Cluster: Meprin A subunit beta precursor; n=39;
           Euteleostomi|Rep: Meprin A subunit beta precursor - Homo
           sapiens (Human)
          Length = 701

 Score = 44.0 bits (99), Expect = 0.006
 Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 7/90 (7%)

Query: 215 NYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNTHFFALHVHLMK 274
           +++W I NF       +      LYSP FY+S  GY F + LN++        ++ HL+ 
Sbjct: 429 HHIWHIRNFTQ----FIGSPNGTLYSPPFYSS-KGYAFQIYLNLAHVTNA--GIYFHLIS 481

Query: 275 TENDDCLEWPFNGRISFVLVNQVYPELSQR 304
             NDD L+WP   + + + +    P++ QR
Sbjct: 482 GANDDQLQWPCPWQQATMTLLDQNPDIRQR 511


>UniRef50_Q1RQ04 Cluster: Zinc finger protein; n=1; Ciona
           intestinalis|Rep: Zinc finger protein - Ciona
           intestinalis (Transparent sea squirt)
          Length = 480

 Score = 42.7 bits (96), Expect = 0.014
 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 10/149 (6%)

Query: 217 VWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRL----NISPQNTHFFALHVHL 272
           +W+I  + ++          +L SP FY++   Y+  V L    +   + TH  +++V L
Sbjct: 328 LWKISEWSSKKIEAEAGKRTVLQSPLFYSARFQYKLAVLLLPNGDGKAKGTHL-SIYVRL 386

Query: 273 MKTENDDCLEWPFNGRISFVLVNQVY-PELSQRDTMMSNTNLKAFSKP----ATEICVRG 327
            K E D  L WP+   I   L++Q   P      T     N    +KP     T      
Sbjct: 387 CKGEYDALLSWPYRLPIEISLIDQSQDPRARINHTYSLRPNPCKENKPFLGRPTSESNPS 446

Query: 328 FGYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
           FG   +  L  +    +++DD + IRV++
Sbjct: 447 FGSQTFMPLDTLNTRDYIRDDAIFIRVSV 475


>UniRef50_UPI0000D55C6F Cluster: PREDICTED: similar to CG4394-PC,
           isoform C; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG4394-PC, isoform C - Tribolium castaneum
          Length = 419

 Score = 41.9 bits (94), Expect = 0.025
 Identities = 24/74 (32%), Positives = 41/74 (55%), Gaps = 4/74 (5%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGY--RFCVRLN-ISPQNTHFFALHV 270
           G+ +W+I +F+ ++ +  KD   +L SP FYT   GY  R  V LN +      +  + +
Sbjct: 266 GHLLWKIADFEDKM-SKAKDCNTVLKSPIFYTHNYGYKIRVLVYLNGLKKWKDRYALISI 324

Query: 271 HLMKTENDDCLEWP 284
           H++K + D  L+WP
Sbjct: 325 HVLKGDFDALLKWP 338


>UniRef50_O62248 Cluster: Putative uncharacterized protein trf-1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein trf-1 - Caenorhabditis elegans
          Length = 462

 Score = 41.9 bits (94), Expect = 0.025
 Identities = 39/150 (26%), Positives = 67/150 (44%), Gaps = 14/150 (9%)

Query: 217 VWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRF--CVRLNISPQNT-HFFALHVHLM 273
           +W+ID  + R +         ++S  F +   GY+   C  L     +     +L+V L+
Sbjct: 266 IWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLL 325

Query: 274 KTENDDCLEWPFNGRISFVLVNQVYPELSQR-------DTMMSNTNLKAFSKPATEICVR 326
           K E D  LEWPF+  I   L++Q  P    R       D      N K  ++P  E    
Sbjct: 326 KGEFDPTLEWPFHRAIKISLLDQ-NPRPEDRVNITYVIDPRKLKANEKFLARPRGERNA- 383

Query: 327 GFGYTEYAVLGDVIRNGFVKDDVLIIRVNI 356
            FG   +  L  +++N +VKDD + +++++
Sbjct: 384 AFGSQSFCSLA-ILQN-YVKDDKIYVQIDV 411


>UniRef50_Q9N586 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 335

 Score = 41.5 bits (93), Expect = 0.033
 Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 6/136 (4%)

Query: 225 TRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNTHF---FALHVHLMKTENDDCL 281
           T + A     ++ +YS  FY+   GY+             F   F++ V LMK E DD L
Sbjct: 170 TVVKATKNKSHRSIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDIL 229

Query: 282 EWPFNGRISFVLVNQVYPELSQRDTMMSN-TNLKAFSKPATEICVRGFGYTEYAVLGDVI 340
           EWPF   ++F +++    EL  +   ++    ++ F +    +    FG+  +  L  V 
Sbjct: 230 EWPFRCDVTFSILSDDKKELLTKTIYVNEMPEIQEFLERPEGLRNGTFGFQNFLPLAKVT 289

Query: 341 RNGFVKDDVLIIRVNI 356
              F  D  + I++ +
Sbjct: 290 E--FAADGDIFIQIKV 303


>UniRef50_UPI00006CBFFF Cluster: hypothetical protein TTHERM_00411410;
            n=3; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00411410 - Tetrahymena thermophila SB210
          Length = 1627

 Score = 39.9 bits (89), Expect = 0.100
 Identities = 38/167 (22%), Positives = 71/167 (42%), Gaps = 19/167 (11%)

Query: 1    MLQKGSLNSGHCPIDNINLSMKVDIFPDNYTKREIQEQ-----RMNCPFSAKGCTVKVTP 55
            ++   SL +  C I N+N   K++ F      R  + Q     + N     +  T ++TP
Sbjct: 1267 IIHAASLENQDCEIQNLNELEKINNFDSKQQDRNTKSQNSKTSQANIETQQQCETNQITP 1326

Query: 56   LDLDAHIAVCEYNQPETSSQPEIHIP-------CSFKPAGCKETFDSQDEMNQHLNNDTQ 108
                      +  QP    QP  H+        C  + +G  E    Q  +   ++N+T 
Sbjct: 1327 TSQQ----YIQNPQPADDKQPHQHLDIDSIKFDCQQENSGEGEVRSKQVSLKNLVSNETP 1382

Query: 109  SHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQTSS 155
             +  +L+ +  E+KI +  S+ N+++K  +A ++ +  D D NQ  S
Sbjct: 1383 QNNQILIESQKELKIGS-KSDQNLNSK--QAFSIQEQLDNDQNQQQS 1426


>UniRef50_Q4SV26 Cluster: Chromosome 8 SCAF13813, whole genome
           shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
           Chromosome 8 SCAF13813, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 672

 Score = 39.5 bits (88), Expect = 0.13
 Identities = 21/47 (44%), Positives = 28/47 (59%), Gaps = 4/47 (8%)

Query: 238 LYSPGFYTSPNGYRFCVRLNISPQNTHFFALHVHLMKTENDDCLEWP 284
           +YSP  Y SP GY + V + +   +   FAL V L+  END+ LEWP
Sbjct: 387 IYSPRLY-SPGGYAYRVGILLQAPS---FALFVQLLSGENDERLEWP 429


>UniRef50_Q9VJW5 Cluster: CG9014-PA; n=2; Sophophora|Rep: CG9014-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 328

 Score = 39.5 bits (88), Expect = 0.13
 Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 11/101 (10%)

Query: 2   LQKGSLNSGHCPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAH 61
           + K  +    CP+D   L     +      +  +   ++ C FS  GC   +   +   H
Sbjct: 43  IDKWMIQKQICPVDRSGLLTSHLVPVSRLMRNMLSRLKIKCTFSQSGCAQMLALEEFRTH 102

Query: 62  IAVCEYNQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQH 102
           +A CE+N       P++ + CS K  G K     +DEM++H
Sbjct: 103 VAACEHN-------PKVVVECS-KGCGMKV---PKDEMSRH 132


>UniRef50_UPI00015B5CBE Cluster: PREDICTED: similar to LOC100036611
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to LOC100036611 protein - Nasonia vitripennis
          Length = 540

 Score = 38.7 bits (86), Expect = 0.23
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%)

Query: 53  VTPLDLDAHIAVCEY-NQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHM 111
           VTPLD + H +  +Y N P+TS Q     P +  P    +   +Q  + Q  NN + S  
Sbjct: 189 VTPLDQEDHSSGSQYSNSPQTSHQSPQTSPTTLSPTSLVQAASAQQGLTQE-NNTSASQQ 247

Query: 112 NLLMNAYSEMKIN 124
           +L +  YS  + N
Sbjct: 248 DLRVAGYSPQQQN 260


>UniRef50_UPI0000E4915D Cluster: PREDICTED: similar to TRAF6; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           TRAF6 - Strongylocentrotus purpuratus
          Length = 529

 Score = 37.9 bits (84), Expect = 0.40
 Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 14/147 (9%)

Query: 153 TSSPPLNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYC 212
           T +  +   +  I  L E    L  +N + D  I  +S  +S+         NE+ L   
Sbjct: 328 TQTEHVQEQACTIHELQETCSRLVGQNADADRKIRELSGDVSSL-------RNELSLA-T 379

Query: 213 MGNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGY--RFCVRL-NISPQNTHFFALH 269
             NY   +  +K ++ +  +D    + SP FYTSP GY  R C+ L     ++  + ++ 
Sbjct: 380 NTNYTGHLQ-WKVQISS--RDFTAPVLSPPFYTSPVGYKLRLCLELRGHVTRSDSYTSIF 436

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQ 296
           + L K E+D  L +PF+   S  L +Q
Sbjct: 437 IMLCKGEHDRNLYFPFSAVCSLTLFDQ 463


>UniRef50_Q54NN4 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 427

 Score = 37.9 bits (84), Expect = 0.40
 Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 16/101 (15%)

Query: 29  NYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYNQPETSSQPEIHIPCSFKPAG 88
           ++ + E Q  ++ C      C +++  ++L  H+ VC          PE+ I C +K  G
Sbjct: 178 DHLESECQSYKIKCTH----CKLEMLRMELSEHLEVC----------PEMTIQCKYKEGG 223

Query: 89  CKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSN 129
           C+ +F  + + N HL ++  +H+  + N   + +I  D S+
Sbjct: 224 CQVSFQRKHQAN-HLASE-NNHIGFIQNIIDQHRILLDESD 262


>UniRef50_UPI00015B6061 Cluster: PREDICTED: similar to tnf receptor
           associated factor; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to tnf receptor associated factor -
           Nasonia vitripennis
          Length = 426

 Score = 37.5 bits (83), Expect = 0.53
 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 4/89 (4%)

Query: 176 EQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRL-DAMLKDH 234
           E       ++ + +SKQ       K   N +M L Y  G  +W+I +F  ++ +A  K+ 
Sbjct: 275 ESTKTHLSLMCSVVSKQQHQITSLKAAMN-KMSLNYS-GTLIWKISDFAAKMAEAKSKEG 332

Query: 235 YKMLYSPGFYTSPNGYRFCVRLNISPQNT 263
            +++ SP FYTS  GY+    L ++   T
Sbjct: 333 VELI-SPPFYTSQYGYKLQASLFLNGNGT 360


>UniRef50_Q54FB9 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 445

 Score = 37.1 bits (82), Expect = 0.70
 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 14/76 (18%)

Query: 33  REIQEQRMNCPFSAKGC--TVKVTPLDLDAHIAVCEYNQPETSSQPEIHIPCSFKPAGCK 90
           ++I E +++C FS+K C    K  P  LDAH  VC          P++ I C+ +   CK
Sbjct: 157 KQIAEHKIDCKFSSKYCLHCDKEIPGQLDAHALVC----------PKVRIQCT-QSESCK 205

Query: 91  ETFDSQDEMNQHLNND 106
           ++F  ++++  H++ D
Sbjct: 206 KSF-PREQLRLHIDQD 220


>UniRef50_A7SBQ8 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 266

 Score = 37.1 bits (82), Expect = 0.70
 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 5/109 (4%)

Query: 214 GNYVWRIDNFKTRLDAMLKDH-YKMLYSPGFYTSPNGYRF-C-VRLN-ISPQNTHFFALH 269
           G  +WR+ NF  ++  +        + S  FYTS  GY+  C   LN    +     +++
Sbjct: 106 GELIWRVSNFNKKVARIRTGRGDDPVCSEPFYTSAFGYKISCWAYLNGRGREEGRSVSVY 165

Query: 270 VHLMKTENDDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSK 318
             +M  E D  L+WP   R +F L++Q  P++  R  ++    +  F +
Sbjct: 166 ACVMYGEYDAVLKWPIRPRYTFALMDQ-NPDVEDRREIVRVRKVNDFKR 213


>UniRef50_Q8I451 Cluster: Putative uncharacterized protein PFE0250w;
            n=5; Plasmodium|Rep: Putative uncharacterized protein
            PFE0250w - Plasmodium falciparum (isolate 3D7)
          Length = 2754

 Score = 36.3 bits (80), Expect = 1.2
 Identities = 27/141 (19%), Positives = 64/141 (45%), Gaps = 3/141 (2%)

Query: 90   KETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKD 149
            K+   S +  + H+NN+  +  + + N  +   + + M+N   +  E  +   ++   K 
Sbjct: 1320 KKKHTSNNNSDGHINNNNSNSDDHINNNNNNSDVPSHMNNPGNNHNESSSQNNYEQKKKK 1379

Query: 150  GNQTSSPPLNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLL 209
             N+ +    +NT  +I+ L  R+  +  RN E   +  N S  +S   +    +N ++  
Sbjct: 1380 MNRINYFSDDNTEDIIKPLNLRIPFINLRNSES--LFVN-SLYISKTNIYNNDKNRDINF 1436

Query: 210  RYCMGNYVWRIDNFKTRLDAM 230
             +   + ++++ N+ T L+ M
Sbjct: 1437 FHIYESNIYKMKNYDTTLNDM 1457


>UniRef50_Q54RH9 Cluster: Putative uncharacterized protein; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1256

 Score = 36.3 bits (80), Expect = 1.2
 Identities = 40/166 (24%), Positives = 64/166 (38%), Gaps = 9/166 (5%)

Query: 7    LNSGHCPIDNINLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCE 66
            +N    P DN+   MKVD    N T ++   Q  N   S    T   T    + ++   E
Sbjct: 1092 INGNEIPGDNVAQQMKVDSDNTNETNQKENNQNDNNSQSINPTTSNQTNKITNDNVNNSE 1151

Query: 67   YNQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINND 126
             +Q     Q   +   +           + +  N + N++    +N LM    E+  NN+
Sbjct: 1152 TDQILNFIQDNNNNNNNNNNNNNNNNNSNSENNNDNNNDNNNQGLNSLMKNEKEIVNNNN 1211

Query: 127  MSNANMD----TKEQEAMALWDAPDKDGNQTSSP----PLNNTSAL 164
             SN N+D    T  Q  ++  D  + + N T  P    P NNT  +
Sbjct: 1212 DSN-NIDNTTNTSNQPTLSNQDDDNNNNNNTIIPQSLNPTNNTEVI 1256


>UniRef50_Q8IDB9 Cluster: Putative uncharacterized protein
           PF13_0314; n=1; Plasmodium falciparum 3D7|Rep: Putative
           uncharacterized protein PF13_0314 - Plasmodium
           falciparum (isolate 3D7)
          Length = 1005

 Score = 35.9 bits (79), Expect = 1.6
 Identities = 15/44 (34%), Positives = 24/44 (54%)

Query: 97  DEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAM 140
           + +N H+NN+  +H N  MN Y    +NN  SN +  T +  +M
Sbjct: 291 NNINNHMNNNINNHTNNNMNNYINHNMNNHYSNYSYGTYDNRSM 334



 Score = 33.5 bits (73), Expect = 8.7
 Identities = 13/33 (39%), Positives = 21/33 (63%)

Query: 99  MNQHLNNDTQSHMNLLMNAYSEMKINNDMSNAN 131
           MN H+N++  +H+N  MN +    +NN M+N N
Sbjct: 246 MNNHVNSNINNHVNNNMNNHMNNNMNNHMNNNN 278


>UniRef50_Q8IBU8 Cluster: Putative uncharacterized protein PF07_0061;
            n=2; cellular organisms|Rep: Putative uncharacterized
            protein PF07_0061 - Plasmodium falciparum (isolate 3D7)
          Length = 2206

 Score = 35.9 bits (79), Expect = 1.6
 Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 92   TFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALW-DAPDKDG 150
            TF S ++ N ++NN T  +MN ++N+      NN+M+NA  +     + +L  +AP    
Sbjct: 1215 TFVS-NKTNVNMNNITNINMNNVINSILNNAANNNMNNAPTNVMHNTSNSLMNNAPTNVI 1273

Query: 151  NQTSSPPLNN 160
            N TS+  +NN
Sbjct: 1274 NNTSNSLMNN 1283


>UniRef50_Q8I5C6 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium falciparum 3D7|Rep: Putative uncharacterized
           protein - Plasmodium falciparum (isolate 3D7)
          Length = 990

 Score = 35.9 bits (79), Expect = 1.6
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 1/82 (1%)

Query: 90  KETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDK- 148
           K+  +   +MN+ +N D    MN+ MN    M +N +M+N   DT    +  L +  +K 
Sbjct: 475 KKEMNMDMDMNKDMNKDMNKDMNMDMNMNMNMNMNMNMNNMGDDTNVDVSDTLNNNLNKN 534

Query: 149 DGNQTSSPPLNNTSALIRALYE 170
           + N+    P      L++  YE
Sbjct: 535 EMNKVDDDPKGFVLNLVKNYYE 556


>UniRef50_A0D7J7 Cluster: Chromosome undetermined scaffold_4, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_4,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 641

 Score = 35.9 bits (79), Expect = 1.6
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 64  VCEYNQPETSSQPEIHIP-CSFKPAGCKETFDSQDEMNQHLN---NDTQSHMNLLMNAYS 119
           + E    +  SQ  + +P C FK   C + FD ++  +Q LN   N+ +    +    YS
Sbjct: 64  ISELEDEKEDSQLNLFLPDCIFKKTDCGQIFDQKENQDQQLNVMSNNEEQFFVVGQKPYS 123

Query: 120 EMKINNDMSNANMD 133
           E K   +  N++ D
Sbjct: 124 EQKQEINCQNSHQD 137


>UniRef50_Q5KB27 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 657

 Score = 35.9 bits (79), Expect = 1.6
 Identities = 13/29 (44%), Positives = 20/29 (68%)

Query: 39  RMNCPFSAKGCTVKVTPLDLDAHIAVCEY 67
           R+ CP SA+GC+  +   DL AHI++C +
Sbjct: 190 RIPCPHSARGCSSIIPRSDLQAHISICPF 218


>UniRef50_UPI0000E87FE6 Cluster: hypothetical protein MB2181_04160;
           n=1; Methylophilales bacterium HTCC2181|Rep:
           hypothetical protein MB2181_04160 - Methylophilales
           bacterium HTCC2181
          Length = 355

 Score = 35.5 bits (78), Expect = 2.1
 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 2/113 (1%)

Query: 123 INNDMSNANMDTKEQEAMALWDAPDKDGNQTSSPPLNNTSALIRALYERVVVLEQRNREQ 182
           I ND+SN  ++T+        +   + G Q SSP LNN   LI+     V + +   R+ 
Sbjct: 157 IQNDISNTLINTEHHWGPYFAELISQTGQQASSPILNNKHRLIKITIPSVNLHKVPPRKI 216

Query: 183 DIVIANISK-QLSAFAVAKMKQNNEMLLRYCMGNYVWRID-NFKTRLDAMLKD 233
           D+ +++  K   ++  V+K   ++E L        V   + N   R+ A +KD
Sbjct: 217 DVYLSSNEKISYASTFVSKAPNSDESLQGKSFYYEVGNTELNIGERIKANIKD 269


>UniRef50_Q8IHR0 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium falciparum 3D7|Rep: Putative uncharacterized
           protein - Plasmodium falciparum (isolate 3D7)
          Length = 915

 Score = 35.5 bits (78), Expect = 2.1
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 94  DSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNAN 131
           +S ++MNQH NN    H N  MN +   K+N    N N
Sbjct: 107 NSNNKMNQHCNNKMNQHCNNKMNQHCNNKMNQHSDNKN 144


>UniRef50_Q24GI4 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1060

 Score = 35.5 bits (78), Expect = 2.1
 Identities = 36/162 (22%), Positives = 75/162 (46%), Gaps = 12/162 (7%)

Query: 94  DSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQT 153
           + +D+  +  NN     + ++    S+   N+ +S+ ++D KE  A    D+   D  + 
Sbjct: 46  EDEDQEEEEENNYDDDDLQIIQR--SQNSFNDRLSDFDLDAKEHFASIYKDSDLNDSKED 103

Query: 154 -SSPPLNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEML--LR 210
            +   L+N S L   L+   V   +++ E +I  +NI K+  +F    ++++ E+   LR
Sbjct: 104 YNDRDLDNNSYLNSVLHISKV---KQSSEFNINQSNIMKEEDSFLKNVIRESEELQKELR 160

Query: 211 YCMGNYVWRIDNFKTRLDAMLKDHYKMLYSPG---FYTSPNG 249
             +  Y W  +  K + + + + +Y    + G   F +S NG
Sbjct: 161 Q-LDMYYWNQNQLKNQQENLNQLNYNQQQTQGINNFISSQNG 201


>UniRef50_Q23RX6 Cluster: Myb-like DNA-binding domain containing
           protein; n=4; Eukaryota|Rep: Myb-like DNA-binding domain
           containing protein - Tetrahymena thermophila SB210
          Length = 1307

 Score = 35.5 bits (78), Expect = 2.1
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 90  KETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDK- 148
           K+   S D+ N++LN D+Q++ N   N      INN + + + DT+ Q  +A    P + 
Sbjct: 319 KKRSSSVDKSNKNLNFDSQNNNNNTNNNKFVDTINNKVKDES-DTENQSELAKKQQPQQL 377

Query: 149 --DGNQTSSPPL 158
             + N TS PP+
Sbjct: 378 ACESNNTSVPPI 389


>UniRef50_A7S0G1 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 1277

 Score = 35.5 bits (78), Expect = 2.1
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 223  FKTRLDAMLKDHYKMLYSPGFYTSPNGYRF-CVRLNISPQNTHFFALHVHLMKTEND 278
            F   L   LKD+ +++ + G+  SPNG  F  + L +SP  ++F + H  ++KT +D
Sbjct: 998  FDMYLPFYLKDNPELVCAKGYVMSPNGNIFLLISLMLSPSASYFMSYHT-ILKTSDD 1053


>UniRef50_A5DDS4 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 396

 Score = 35.5 bits (78), Expect = 2.1
 Identities = 21/106 (19%), Positives = 48/106 (45%), Gaps = 4/106 (3%)

Query: 62  IAVCEYNQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEM 121
           + +C  N  E S  P++H  C         +++ + +  + + ND     +  MN   E 
Sbjct: 195 VLLCASNTREIS--PDLHGRCELLFEDTNYSYEYESDFEERIENDLDELSDQEMNEIEEA 252

Query: 122 KI-NNDMSNANMDTKEQEA-MALWDAPDKDGNQTSSPPLNNTSALI 165
              N++ S++N +T   ++  +  D+P+   + T  P ++ + + I
Sbjct: 253 SSQNSETSSSNSETSSSDSETSSSDSPNSPNSPTDCPSVSGSQSFI 298


>UniRef50_Q7QFB1 Cluster: ENSANGP00000010011; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000010011 - Anopheles gambiae
           str. PEST
          Length = 190

 Score = 35.1 bits (77), Expect = 2.8
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 214 GNYVWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNT---HFFALHV 270
           G+ +WRIDNF  RL    K+   M+  P F   P GY   + +++    T         +
Sbjct: 43  GHVMWRIDNFANRLQ-QSKELETMMKGPIFTNYPYGYMLQLEVSLYGIGTWRGRNLIAGL 101

Query: 271 HLMKTENDDCLEWP 284
            ++    D+ LEWP
Sbjct: 102 TILPGPYDELLEWP 115


>UniRef50_A7RGH1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 327

 Score = 35.1 bits (77), Expect = 2.8
 Identities = 36/136 (26%), Positives = 60/136 (44%), Gaps = 14/136 (10%)

Query: 8   NSGHCPIDNINLS-MKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCE 66
           +  +CPID   L+ +++   P    K  + +  ++C     GC V V    L +H+A C+
Sbjct: 49  HQNNCPIDRRTLTPLQLKQVP-RILKNLLSKLVISCDNVTFGCEVMVRLDGLQSHLAQCD 107

Query: 67  YNQPETSSQPEIHIPCSFKPAGCKETFDSQDEMN--QHLNNDTQSHMNLLMNAYSEMKIN 124
           +N       P+  + C  K  G    FD   + N  + LN   QS  NL M A  + +I+
Sbjct: 108 HN-------PKRPVQCD-KGCGLVVPFDELQQHNCVRELNTIIQS-QNLKM-AELQAQID 157

Query: 125 NDMSNANMDTKEQEAM 140
           +     N   +E + M
Sbjct: 158 DQRQQLNEQKREMQMM 173


>UniRef50_P22265 Cluster: Protein teashirt; n=3; Sophophora|Rep:
           Protein teashirt - Drosophila melanogaster (Fruit fly)
          Length = 954

 Score = 35.1 bits (77), Expect = 2.8
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 89  CKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKE 136
           C E+F S  EM +H+  +TQ + N+L    S + I +  +NAN D KE
Sbjct: 471 CGESFRSLGEMTKHMQ-ETQHYTNILSQEQS-ISIKSGNANANSDAKE 516


>UniRef50_UPI00006CFBCB Cluster: hypothetical protein
           TTHERM_00487170; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00487170 - Tetrahymena
           thermophila SB210
          Length = 1005

 Score = 34.7 bits (76), Expect = 3.7
 Identities = 17/73 (23%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 79  HIPCS-FKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQ 137
           HIPCS +     +++F+ ++  N  +N +    ++LL +     K+N  +   +++TK+ 
Sbjct: 592 HIPCSDYSEQQLEDSFEIRELQNHLMNLENVQALDLLNSKLENEKLNRKIFKESLNTKDS 651

Query: 138 EAMALWDAPDKDG 150
           E    ++   K G
Sbjct: 652 EQELFYNKEKKIG 664


>UniRef50_Q24E40 Cluster: Leucine Rich Repeat family protein; n=1;
           Tetrahymena thermophila SB210|Rep: Leucine Rich Repeat
           family protein - Tetrahymena thermophila SB210
          Length = 1391

 Score = 34.7 bits (76), Expect = 3.7
 Identities = 40/145 (27%), Positives = 62/145 (42%), Gaps = 9/145 (6%)

Query: 68  NQPETSSQPEIHIP-CSFKPAGCKETFDS-QDEMNQHL-NNDTQSHMNLLMNAYSEMKIN 124
           NQ  T    + H P  SF+ +  K  F S +   NQ   N+D Q    L  N  + + I 
Sbjct: 36  NQTNTKVNLQPHTPKSSFRNS--KINFQSLRGSPNQSFYNSDDQQQQPLSKNQDAIINIQ 93

Query: 125 NDMSNANMDTKEQEAMALWDAPDKDGNQTSSPPLNNTSALIRALYERVVVLEQRNREQDI 184
           +   N+N++T  Q    L D  +K   Q S      TS   ++LY  V    +R+  Q +
Sbjct: 94  DQFQNSNLNTYSQPNKGLHDQVNKP-QQISRDLKRQTS---KSLYNDVNNASRRSYLQHL 149

Query: 185 VIANISKQLSAFAVAKMKQNNEMLL 209
                   L AF  +K  Q+N+ ++
Sbjct: 150 QNDEQKLFLQAFENSKSNQDNKAII 174


>UniRef50_Q232U4 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1038

 Score = 34.7 bits (76), Expect = 3.7
 Identities = 29/140 (20%), Positives = 64/140 (45%), Gaps = 4/140 (2%)

Query: 97  DEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQTSSP 156
           DE+N+ + +D ++          E+K N +   A+++ K +E +    + + +  Q+   
Sbjct: 198 DELNKKIMDDLKNQKGQSQQMLEELKKNYENKIADLEGKNKELLQKIQSLEAE-IQSLRM 256

Query: 157 PLNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNY 216
            LNN    ++ + +    L++    Q + I    K++    V K +QN E + +    N 
Sbjct: 257 QLNNRETELKTVSDERNQLKKMTERQALQIQEQQKEIDGLKVEK-QQNFEKIKQLEAANQ 315

Query: 217 VW--RIDNFKTRLDAMLKDH 234
               +I +++ +LD   KD+
Sbjct: 316 ALEKKIKDYQDQLDKYGKDN 335


>UniRef50_Q22P57 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1103

 Score = 34.7 bits (76), Expect = 3.7
 Identities = 24/112 (21%), Positives = 49/112 (43%), Gaps = 6/112 (5%)

Query: 97  DEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPD--KDGNQTS 154
           +E+NQ     +QS  + L+   +E+  NND  N         +++ + +P   K+G+Q  
Sbjct: 457 NELNQSEGKKSQSRNSKLLKIQNELLHNNDSENVENSANHVFSLSTFHSPRFIKNGDQNG 516

Query: 155 SPPLNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNE 206
           +  + NT        +R  +L    +   + +  +  QL  +A   + Q+ E
Sbjct: 517 NLLVQNTPRTT----DREFLLSNNGKNNHVDMPELQMQLQPYAKQSLMQDVE 564


>UniRef50_Q22EZ0 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 936

 Score = 34.7 bits (76), Expect = 3.7
 Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 1/53 (1%)

Query: 102 HLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQTS 154
           H N   Q+H NL MN  S   +NN + N  ++ K    M  ++    D NQ S
Sbjct: 379 HKNQQNQTHENLYMNYLSNKNVNNILFNTPINQKRNRIMN-YEITPWDNNQVS 430


>UniRef50_A0DXA7 Cluster: Chromosome undetermined scaffold_68, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_68, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1447

 Score = 34.7 bits (76), Expect = 3.7
 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 7/122 (5%)

Query: 90   KETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKD 149
            +   DS  E  + +N D    +N L    +E+K+ ND+ NA +   EQ  + L   P + 
Sbjct: 928  RHKLDSYPEFEERIN-DQIGKINSLEKDNNELKLQNDILNAQISQLEQNIIKL--QPLEQ 984

Query: 150  GNQTSSPPLNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAV-AKMKQNNEML 208
                    +NN +  I     R   LE    +Q+    +  K++  F +  K +QN EM+
Sbjct: 985  QVTLLREIINNDNREISLWQTRFQDLENERSQQN---EDYRKKIDQFKIELKDQQNLEMI 1041

Query: 209  LR 210
            ++
Sbjct: 1042 IK 1043


>UniRef50_A0DAY9 Cluster: Chromosome undetermined scaffold_43, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_43,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 696

 Score = 34.7 bits (76), Expect = 3.7
 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 97  DEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQTSSP 156
           D++NQ LNN +   +N L+N  ++  I    SN   + +  +   L      D ++ S+ 
Sbjct: 247 DQINQQLNNQSTIELNKLLNIKNKNNILYQFSNTLENDQFHQQFQLM---QYDWSEFSTG 303

Query: 157 PLNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRY 211
            L + + + R    ++  +EQ +  +DI I N+  Q   F    + Q  E  L+Y
Sbjct: 304 QLGDVAYICRQ-KNQIEQIEQESIYKDIQITNMLNQSKCFTNMMIIQ-FESFLKY 356


>UniRef50_Q0CDL1 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus terreus NIH2624|Rep: Putative
           uncharacterized protein - Aspergillus terreus (strain
           NIH 2624)
          Length = 752

 Score = 34.7 bits (76), Expect = 3.7
 Identities = 35/148 (23%), Positives = 59/148 (39%), Gaps = 14/148 (9%)

Query: 60  AHIAVCEYNQPETSSQPEIHIPCSFKP----AGCKETFDSQDEMNQHLNNDTQSHMNLLM 115
           A +     + P+TS   ++ IP +F P    A C+E         Q +  D     N L 
Sbjct: 382 AEVFTIRLDSPDTSKSLDVKIPSTFYPDRYLASCREMSRDFRARRQEMRQDILKIEN-LA 440

Query: 116 NAYSEMKINNDMSNANMDTKEQEAMALWDAP------DKDGNQTSSPP---LNNTSALIR 166
           N +S  K        +    E+  +AL   P      D D NQ ++     +N    +  
Sbjct: 441 NRFSVTKSLASKGLTSKQVLEKATVALSALPQNLSQSDNDPNQITAEAERVVNELRQVCS 500

Query: 167 ALYERVVVLEQRNREQDIVIANISKQLS 194
            L +++  LE+R ++    + N SK L+
Sbjct: 501 KLEDKLQELERRKQDATEALRNYSKALT 528


>UniRef50_Q5A216 Cluster: Probable kinetochore protein NDC80; n=1;
           Candida albicans|Rep: Probable kinetochore protein NDC80
           - Candida albicans (Yeast)
          Length = 788

 Score = 34.7 bits (76), Expect = 3.7
 Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 5/96 (5%)

Query: 90  KETFDS-QDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDK 148
           K  FD  Q+++NQ LNN  Q H NLL N Y E  +NN +   +   K+  A+       K
Sbjct: 382 KIKFDQLQEKLNQELNNVEQQHENLL-NKYHE--LNNQLKIRDDALKKTVALEEDYMKLK 438

Query: 149 DGNQTSSPPLNNTSALIRALYERVVVL-EQRNREQD 183
             NQ     +   +  +  L   V+   EQ N+ QD
Sbjct: 439 SYNQNVEKMMPEWNKKLEQLSNEVISYEEQMNKLQD 474


>UniRef50_UPI00015B491A Cluster: PREDICTED: similar to conserved
           hypothetical protein; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to conserved hypothetical protein -
           Nasonia vitripennis
          Length = 595

 Score = 34.3 bits (75), Expect = 5.0
 Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 8/123 (6%)

Query: 15  DNINLSMKVDIFPDNYTKREIQEQRMNCPFS-AKGCTVKVTPLDLDAHIAVCEYNQP--E 71
           DNIN   +    P N      + Q  +  FS A   T K   LD   +     Y+Q    
Sbjct: 285 DNIN-RFETTTKPTNAISNRPEPQSYSAQFSQATSATTKQPSLDYQLYNQGDNYDQRIYN 343

Query: 72  TSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLN----NDTQSHMNLLMNAYSEMKINNDM 127
             +   +H P S   A    T  SQ++ N H N    N+  ++ N   N Y   K+ +  
Sbjct: 344 NYNSNYVHRPNSTTHASSSTTVPSQNKNNNHYNNYNDNNNYNNYNTFNNNYPSKKLADYN 403

Query: 128 SNA 130
           SN+
Sbjct: 404 SNS 406


>UniRef50_UPI00005885C0 Cluster: PREDICTED: similar to TRAF4
          protein, partial; n=1; Strongylocentrotus
          purpuratus|Rep: PREDICTED: similar to TRAF4 protein,
          partial - Strongylocentrotus purpuratus
          Length = 152

 Score = 34.3 bits (75), Expect = 5.0
 Identities = 15/44 (34%), Positives = 22/44 (50%)

Query: 25 IFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYN 68
          I+PD+    +IQ   + C F   GC      + L AH+  C+YN
Sbjct: 11 IYPDDKMSGDIQMLMVRCHFYKDGCRWTDQLMTLQAHLESCQYN 54


>UniRef50_UPI0000660B2D Cluster: Meprin A subunit alpha precursor
           (EC 3.4.24.18) (Endopeptidase-2) (N-
           benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit
           alpha) (PABA peptide hydrolase) (PPH alpha).; n=1;
           Takifugu rubripes|Rep: Meprin A subunit alpha precursor
           (EC 3.4.24.18) (Endopeptidase-2) (N-
           benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit
           alpha) (PABA peptide hydrolase) (PPH alpha). - Takifugu
           rubripes
          Length = 538

 Score = 34.3 bits (75), Expect = 5.0
 Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 217 VWRIDNFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNTHF---FALHVHLM 273
           VW+I NF   L  +       + S  F  +P GY F + +  + ++  +    ++ +HL 
Sbjct: 222 VWQISNFTGHLATVAAG--SSIKSQCF-VNPEGYSFGISVYPNGRDLDYPDYVSMTMHLC 278

Query: 274 KTENDDCLEWPF-NGRISFVLVNQ 296
             END  LEWP  N +++ + ++Q
Sbjct: 279 SGENDAILEWPVKNRQVTIIAMDQ 302


>UniRef50_Q9NGW8 Cluster: Developmental protein DG1037; n=2;
           Dictyostelium discoideum|Rep: Developmental protein
           DG1037 - Dictyostelium discoideum (Slime mold)
          Length = 609

 Score = 34.3 bits (75), Expect = 5.0
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 4/64 (6%)

Query: 68  NQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDM 127
           N P  S Q   H   S  P  C+ETF+S +  N + NN+  ++ N   N  +    NN+ 
Sbjct: 332 NNPSPSKQQPPH-SFSLIPPICEETFESNNNNNNNNNNNNNNNNN---NNNNNNNNNNNN 387

Query: 128 SNAN 131
           SN N
Sbjct: 388 SNNN 391


>UniRef50_Q557K0 Cluster: Putative uncharacterized protein; n=2;
           Dictyostelium discoideum|Rep: Putative uncharacterized
           protein - Dictyostelium discoideum AX4
          Length = 450

 Score = 34.3 bits (75), Expect = 5.0
 Identities = 23/104 (22%), Positives = 47/104 (45%), Gaps = 2/104 (1%)

Query: 35  IQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYNQPETSSQPEIHIPCSFKPAGCKETFD 94
           I+ +++N    ++  T+ +T     A I     N    +  P   I C +K  GC + F 
Sbjct: 179 IERKKLNKHIESECDTLMITCSKCSASIGKKLMNHHLETDCPMEEISCLYKAGGCNKRF- 237

Query: 95  SQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQE 138
            + +++QHL ++  +H+  + N     K+  D  N +    E++
Sbjct: 238 LRSQLSQHL-SENNNHIFYIQNVMDLHKLQLDECNQDYRKLEKQ 280


>UniRef50_Q54LU4 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1214

 Score = 34.3 bits (75), Expect = 5.0
 Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 98  EMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDT-KEQEAMALWDAPDKDGNQ-TSS 155
           ++N + NN+  S+ N   N+ + +  NN+  N  MDT K+     +   P++  NQ T S
Sbjct: 120 DLNNNNNNNNNSNNNTNNNSNNNLMNNNNDYNYLMDTYKQPSPHQINQRPNQSSNQSTPS 179

Query: 156 PPLNNTSALIRALYERVVVLEQRNRE 181
              NNT+ +    Y+ + ++ Q+ ++
Sbjct: 180 FSCNNTNYIDH--YQNIDLMNQQQQQ 203


>UniRef50_Q23RY6 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 2736

 Score = 34.3 bits (75), Expect = 5.0
 Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 19/139 (13%)

Query: 158  LNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYCMGNYV 217
            L+N   L+ +  + V++L+  N+   ++   IS +  AF+V    Q+ ++   Y  G+ +
Sbjct: 1170 LDNQKLLVASRQQGVLILDISNKSNPVLFQRISIKGHAFSVQLTNQDQQLF--YANGDTI 1227

Query: 218  WRID----NFKTRLDAMLKDHYKMLYSPGFYTSPNGYRFCVRLNISPQNTHFF------A 267
            +  +    N    +  +  DH   LY  G Y     YR+  R  +S  ++ FF       
Sbjct: 1228 FEYEKVTPNLSQDIPNLSNDHIAKLYQIGNYQ----YRW--RCYVSQDDSFFFGAFDKVG 1281

Query: 268  LHVHLMKTE-NDDCLEWPF 285
            L V+ +KT+ N+  +  P+
Sbjct: 1282 LFVYSLKTDPNNQAIINPY 1300


>UniRef50_A0CJC8 Cluster: Chromosome undetermined scaffold_2, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_2,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 1002

 Score = 34.3 bits (75), Expect = 5.0
 Identities = 37/176 (21%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 68  NQPETSSQPEIHIPCSFKPAGCKETFDSQDE--MNQHLNNDTQSHMNLLMNAYSEMKINN 125
           +Q + S QP+ H   S  P      F+      MNQ L      ++N+L N   +   N 
Sbjct: 767 SQSQDSHQPDTH---SIAPKKVSSQFEKMRTSFMNQKLKTGLGQNVNILRNQNQDDDSNG 823

Query: 126 DMSNANMDTKEQEAMALWDAPDKDGNQTSSPPLNNTSALIRALYERVVVLEQRNREQDIV 185
            + N  + + ++     +D  D   +  +    N T+  I+   +      Q N    +V
Sbjct: 824 TLQNPYV-SYQRNTENEFDPRDYSQSNATFNQYNLTNNTIK---QGSSPYTQNNLRTSVV 879

Query: 186 IANISKQLSAFAVAKMKQNNEMLLRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYSP 241
             + +  L        +Q+N   ++   GNY    +N K +    L+ +  +LY+P
Sbjct: 880 RTDTNMPLKG---NHQQQHNHPSVKIANGNYYVENENDKNQFQGQLQTNGTILYAP 932


>UniRef50_P10071 Cluster: Zinc finger protein GLI3; n=44;
           Eumetazoa|Rep: Zinc finger protein GLI3 - Homo sapiens
           (Human)
          Length = 1580

 Score = 34.3 bits (75), Expect = 5.0
 Identities = 13/41 (31%), Positives = 24/41 (58%)

Query: 66  EYNQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNND 106
           E ++ E+  +PE+    +    GC   FD+Q+++  H+NND
Sbjct: 464 EGDKDESKQEPEVIYETNCHWEGCAREFDTQEQLVHHINND 504


>UniRef50_UPI00006CFC12 Cluster: hypothetical protein
           TTHERM_00530170; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00530170 - Tetrahymena
           thermophila SB210
          Length = 734

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 26/124 (20%), Positives = 54/124 (43%), Gaps = 3/124 (2%)

Query: 83  SFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMAL 142
           SFK    K   D Q + N+   N   +H+N+      ++++++ + + +   + Q    L
Sbjct: 176 SFKLTKQKSLLDLQKDENKQFENQN-NHININNKNSFKLRVSSSLKDLSKSQRFQNINNL 234

Query: 143 WDAPDKDGNQTSSPPLNNTSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMK 202
            +   +         L NTS  ++ L+E  V +E + +E ++ I + +  L    + K  
Sbjct: 235 DEQNLQKAFDRMQKSLINTS--LKQLHENQVFVEDKEKEVELNIQSYNVNLDKIQMLKPS 292

Query: 203 QNNE 206
            N E
Sbjct: 293 VNEE 296


>UniRef50_UPI00006CA3DB Cluster: hypothetical protein
           TTHERM_00526500; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00526500 - Tetrahymena
           thermophila SB210
          Length = 470

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 67  YNQPETSSQPEIHIPCSFKPAGCKETFDSQ-DEMNQHLNNDTQSHMNLLMNAYSEMKINN 125
           YN   T+   +       K   C+   +     +N ++NND Q H  +     ++   ++
Sbjct: 119 YNPQTTAQLHDTRCEQYMKDDNCESLVEENLFNLNYNMNNDNQKHTEIENQNINQQNQSS 178

Query: 126 DMSNANMDTKEQEAMALWDAPDKDGNQTSSPPL 158
           ++ +   D  EQ  +  +D   K  N T SPPL
Sbjct: 179 NIFSEPQDCAEQNNIQSFDVKSKLVN-TQSPPL 210


>UniRef50_Q9PQX1 Cluster: MBA N-terminal paralog; n=1; Ureaplasma
           parvum|Rep: MBA N-terminal paralog - Ureaplasma parvum
           (Ureaplasma urealyticum biotype 1)
          Length = 499

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 1/71 (1%)

Query: 91  ETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDG 150
           + F+   E   H+NN   SH  L+ N    + I N+ +NA +  K +E M   D   +  
Sbjct: 424 KVFNLDKEQKYHINNVMFSH-KLIPNLLKALDIKNNTTNAELIKKIKENMTAIDEKTQTN 482

Query: 151 NQTSSPPLNNT 161
             T+  PL+ T
Sbjct: 483 LNTNYIPLSLT 493


>UniRef50_Q7VFK1 Cluster: Putative uncharacterized protein; n=1;
           Helicobacter hepaticus|Rep: Putative uncharacterized
           protein - Helicobacter hepaticus
          Length = 255

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 4/67 (5%)

Query: 278 DDCLEWPFNGRISFVLVNQVYPELSQRDTMMSNTNLKAFSKPATEICVRGFGYTEYAVLG 337
           D+C     +G +S  L   +YP L+  +++      + +   A +IC  G GY  +A+L 
Sbjct: 25  DECYHSLKDGALSETLYKHIYPSLAHLESVYGGLPSEIY---ALDICF-GLGYNTFALLS 80

Query: 338 DVIRNGF 344
            +++ G+
Sbjct: 81  TLVQKGY 87


>UniRef50_Q8IBH0 Cluster: Putative uncharacterized protein
           MAL7P1.157; n=1; Plasmodium falciparum 3D7|Rep: Putative
           uncharacterized protein MAL7P1.157 - Plasmodium
           falciparum (isolate 3D7)
          Length = 466

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 3/58 (5%)

Query: 94  DSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGN 151
           ++ DEM+  +NN   + MN  MN     K+NN M+N  M+ K    M   D  D+D N
Sbjct: 151 NTNDEMDDEMNNKMNNKMNNKMNDKMNDKMNNKMNN-KMNDKMNNKMN--DEMDEDVN 205


>UniRef50_Q7RFF8 Cluster: Putative uncharacterized protein PY04748;
           n=4; Plasmodium (Vinckeia)|Rep: Putative uncharacterized
           protein PY04748 - Plasmodium yoelii yoelii
          Length = 1175

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 4/112 (3%)

Query: 94  DSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQT 153
           DS  ++N   NN+  +  N  ++       +ND+SN N+ +K +E M L    D +   +
Sbjct: 266 DSNHDINITNNNENMNEQNNKIDTNDSKHDSNDLSN-NLTSKNKEKMEL--LGDSENKSS 322

Query: 154 SSPPLNNTSALIRALYERVVVLEQRNR-EQDIVIANISKQLSAFAVAKMKQN 204
             P +       R +Y+R  +   + + + D +   ISK++      K+ QN
Sbjct: 323 IIPHVFPDPNNNRPVYKRKELKSDKMKTKADFIDNEISKKIKNSMYVKIGQN 374


>UniRef50_Q55GA0 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 462

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 29/135 (21%)

Query: 18  NLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTV---KVTPLDLDAH------------- 61
           +L  ++DI   +Y   + ++ R  CP+   GCT+     + +D+++H             
Sbjct: 169 DLCSELDICGYDYRYNQSEKHRDECPYGIIGCTLCGKDCSRVDIESHTENHCPKLLVKCP 228

Query: 62  -------IAVCEYNQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLL 114
                  IA C+ +   +     I I C  K +GCKE    ++++  HL++D  +H+  +
Sbjct: 229 TCNQDQLIARCDLDDHLSVDCAMIEIDCILKESGCKERV-KRNQLANHLSSD--NHLLFI 285

Query: 115 MNAYSEMKINNDMSN 129
            N +++    ND+ N
Sbjct: 286 NNQFNQ---QNDIIN 297


>UniRef50_Q54RG7 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 168

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 25/125 (20%), Positives = 55/125 (44%), Gaps = 6/125 (4%)

Query: 94  DSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQT 153
           DS  + N + N+++ S+ N   N+ S    NN+ +N N +          +  + + N  
Sbjct: 44  DSDSDSNSNSNSNSNSNSNSNSNSNSNSNSNNNNNNTNNNNNNNNNNNNNNNNNNNNNNN 103

Query: 154 SSPPLNN--TSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRY 211
           ++   N+  +  +++ + ERV+++   N E+   I  I + + +      +  N     Y
Sbjct: 104 NNNNNNSVFSELILKLIAERVILINNYNIEKIEEIKGIPELMKSITSTTAETKN----NY 159

Query: 212 CMGNY 216
             G+Y
Sbjct: 160 YSGSY 164


>UniRef50_Q54PJ2 Cluster: Sphingosine kinase; n=2; Dictyostelium
           discoideum|Rep: Sphingosine kinase - Dictyostelium
           discoideum AX4
          Length = 760

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 26/103 (25%), Positives = 50/103 (48%), Gaps = 2/103 (1%)

Query: 90  KETFDSQDEMNQHLNNDTQSHMNLLMN-AYSEMKINNDMSNANMDTKEQ-EAMALWDAPD 147
           KE   S    N++ NN+  S  N++ N + + +  NN +SN N +T    +     +  +
Sbjct: 36  KEEISSSSIENKNNNNNNTSTNNVIPNESNNNISNNNVISNENNNTNNNTDNNTDNNNNN 95

Query: 148 KDGNQTSSPPLNNTSALIRALYERVVVLEQRNREQDIVIANIS 190
            + N  ++ P+ + +   ++L E+   L + N+EQ I   N S
Sbjct: 96  NNNNNNNNEPVTSFTVNNKSLIEKEPTLFEFNQEQQIKYKNKS 138


>UniRef50_Q54NA9 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 923

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 1/54 (1%)

Query: 110 HMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQTSSPPLNNTSA 163
           +MNL+     E ++N D++NAN  TK ++ +    + D +    +S P+N TS+
Sbjct: 703 NMNLISEFIKE-QLNLDLTNANTPTKVKKTIKTTTSKDNNNKIITSSPVNTTSS 755


>UniRef50_Q9VVV9 Cluster: Protein naked cuticle; n=2; Drosophila
           melanogaster|Rep: Protein naked cuticle - Drosophila
           melanogaster (Fruit fly)
          Length = 928

 Score = 33.9 bits (74), Expect = 6.5
 Identities = 18/74 (24%), Positives = 30/74 (40%)

Query: 96  QDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQTSS 155
           Q +  Q  + D +++ NL+    SE     D        K+Q+   L D P         
Sbjct: 753 QQQQQQRSSKDYKNYGNLIYAKLSEQLQQKDREQRRQRHKQQQHQMLQDQPKDASRSEQR 812

Query: 156 PPLNNTSALIRALY 169
           PP +N+S+    +Y
Sbjct: 813 PPTSNSSSAGSKIY 826


>UniRef50_Q81ZL2 Cluster: SMC protein; n=4; Coxiella burnetii|Rep:
           SMC protein - Coxiella burnetii
          Length = 1169

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 33/153 (21%), Positives = 64/153 (41%), Gaps = 9/153 (5%)

Query: 71  ETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLN-NDTQSHMNLLMNAYSEMKINNDMSN 129
           +T SQ E+      K   C+      ++  Q L  N  Q  ++ L+N  + +   +++ N
Sbjct: 393 QTMSQLEV---MRTKREHCERQLTDLEKSKQQLQQNLKQLQLDQLLNEIAPLSSQSELLN 449

Query: 130 ANMDTKEQEAMALWD--APDKDGNQTSSPPLNNTSALIRALYERVVVLEQRNREQDIVIA 187
           A +   + +  +L +  A  +D NQT+   L      ++AL  R   LE     Q   + 
Sbjct: 450 AELSDSQSKLQSLAETIASRRDANQTTREELQTQRRELQALEARAASLEAL---QKAALG 506

Query: 188 NISKQLSAFAVAKMKQNNEMLLRYCMGNYVWRI 220
               ++S +  ++  + N  L +  + N  W I
Sbjct: 507 ESDGKISEWLSSQQLKENPRLGQKLVVNPGWEI 539


>UniRef50_A4CKU3 Cluster: OmpA family protein; n=1; Robiginitalea
           biformata HTCC2501|Rep: OmpA family protein -
           Robiginitalea biformata HTCC2501
          Length = 425

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 14/50 (28%), Positives = 25/50 (50%)

Query: 94  DSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALW 143
           D++   +Q  +     ++ L+   YSE +I  D+ N N  T+  E+ A W
Sbjct: 31  DARHTASQEADKRVDDYLKLVKLGYSEREIYEDLGNVNFLTENYESAAFW 80


>UniRef50_Q8ILJ3 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium falciparum 3D7|Rep: Putative uncharacterized
           protein - Plasmodium falciparum (isolate 3D7)
          Length = 1320

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 24/104 (23%), Positives = 49/104 (47%), Gaps = 6/104 (5%)

Query: 90  KETFDSQDEMNQHLNND-TQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDK 148
           KET+  +DE    LNND T+   ++   + + +K  +D++    DT   +     ++ +K
Sbjct: 472 KETYAQKDEKIDELNNDKTEEEKHIPTESVNNIKKESDINEQIDDTSNNDN----NSDNK 527

Query: 149 DGNQTSSPPLNNTSALIRALYERVVVLE-QRNREQDIVIANISK 191
                     N+T+     + E V+  + +R ++ +I I N+ K
Sbjct: 528 KDTDEGKQKENDTNVQEECVQENVINYDKEREQKYEIAINNLIK 571


>UniRef50_Q8IKW4 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium falciparum 3D7|Rep: Putative uncharacterized
           protein - Plasmodium falciparum (isolate 3D7)
          Length = 1504

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 28/99 (28%), Positives = 56/99 (56%), Gaps = 10/99 (10%)

Query: 95  SQDEMNQHLNNDTQSHMNLLMNAYSEMKINND---MSNANMDTK-EQEAMALWDAPDKDG 150
           S+  +N ++NND ++     MN++S+  IN +   MSN ++  K  QE   L D  +++ 
Sbjct: 360 SEKSLNPYVNNDLENSTGSPMNSFSQSNINTENTLMSNNDIINKVVQEGDVLMD--EQES 417

Query: 151 NQTS-SPPLNNTSALIRALYERVVVLEQRNREQDIVIAN 188
           +Q + +  +N TS +IR    R +  ++++ ++DI  +N
Sbjct: 418 SQLNCANVMNVTSKVIR---RRRIRSKKKSVDKDIKGSN 453


>UniRef50_Q8IDG0 Cluster: Putative uncharacterized protein
           PF13_0284; n=1; Plasmodium falciparum 3D7|Rep: Putative
           uncharacterized protein PF13_0284 - Plasmodium
           falciparum (isolate 3D7)
          Length = 356

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 12/162 (7%)

Query: 90  KETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKD 149
           +ET D +++M    N+   SH   + N   E+   N+ +N     +  E     D+  KD
Sbjct: 159 EETTDMENDMLYIHNDSLPSHQPTINNNTQELYHINNYNNNIYFYEPCEKDNYLDSSIKD 218

Query: 150 ------GNQTSSPPLNNTSALIRA-----LYERVVVLEQRNREQDIVIANISKQLSAFAV 198
                  N TS    N T+ +I        YE   +    N  +     N  KQL    +
Sbjct: 219 IYFDIYSNDTSENIKNETNDIINVDQKGNKYEENNINISNNTHEYKTFVNDDKQLLLDHI 278

Query: 199 AKMKQNNEMLLRYCMGNYVWRIDNFKTRLDAMLKDHYKMLYS 240
            +++  N + L   +  Y   ID  K + D  +K+H +++ S
Sbjct: 279 KRLEYQNNIFLNNMLNMYYVCIDYIKLQ-DDKIKEHEQVINS 319


>UniRef50_Q6LF05 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium falciparum 3D7|Rep: Putative uncharacterized
           protein - Plasmodium falciparum (isolate 3D7)
          Length = 372

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 25/120 (20%), Positives = 53/120 (44%), Gaps = 2/120 (1%)

Query: 17  INLSMKVDIFPDNYTKREIQEQRMNCPFSAKGCTVKVTPLDLDAHIAVCEYNQPETSSQP 76
           I +S+ +D FP NY + + +E   N  F  +        LD++      +YN    + + 
Sbjct: 68  IQVSLCIDRFPINYVQEKFEEDFQN--FKDEWLIKTNNNLDVNEEFFHMKYNLSNLNEKQ 125

Query: 77  EIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKE 136
           + +              ++ DE N+H+ N+T ++ N   N  +     ++++N N++  E
Sbjct: 126 KDNDNNDDGDDDGNNEKENLDEQNEHMENNTYNNNNNNNNNNNTKHKLDNITNNNVNNME 185


>UniRef50_Q54VP0 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 2176

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 5/76 (6%)

Query: 90  KETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMAL-WDAPDK 148
           KET DS++  N  LNN+   + + L N  +    NN+ +N   D KE++  +L  D+   
Sbjct: 758 KETLDSKNFNNLILNNNNNLNNSNLNNNNNNSNNNNEQNN---DVKEKDIESLIRDSTIS 814

Query: 149 DGNQTS-SPPLNNTSA 163
           + N T+ SP ++++S+
Sbjct: 815 EANVTAISPTISSSSS 830


>UniRef50_Q54R73 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1247

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 18/70 (25%), Positives = 35/70 (50%)

Query: 94  DSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQT 153
           ++ +  N + NN+  ++ N + N  S    NN+ +N+N +          + P ++G  +
Sbjct: 78  NNNNNNNINNNNNNINNNNNINNNNSNNNNNNNNNNSNSNNSINSNSYKVNTPTQNGKSS 137

Query: 154 SSPPLNNTSA 163
            SPPL N +A
Sbjct: 138 HSPPLINANA 147


>UniRef50_Q23CN2 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1206

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 32/151 (21%), Positives = 66/151 (43%), Gaps = 17/151 (11%)

Query: 85  KPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWD 144
           +P  C  + +     NQ  NN+  ++ N+  N  S    NN+  N N      +++   D
Sbjct: 117 QPQECSSSQNKSSSTNQ--NNNNSNNNNISNNNNSNNNSNNN--NNNQKITSMQSLNQID 172

Query: 145 APDKDGNQTSSPPLNNTSALIRALYERVVVLEQR-----NREQDIVIANISKQLSAFAVA 199
           + +++ N+ S P  NN     ++    V ++++R     N++Q     N ++      +A
Sbjct: 173 SRNQNKNRVSQPNSNNIQTNTQS--NSVKIIQERNSASQNQQQQQNTQNGTQNQQQKVIA 230

Query: 200 KMKQNNEMLLRYCMGNYVWRIDNFKTRLDAM 230
           K+  N +        N V +I++  T  ++M
Sbjct: 231 KLNSNTQ------SNNQVQKINSVSTNNNSM 255


>UniRef50_A7S9A1 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 2636

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 22/100 (22%), Positives = 39/100 (39%)

Query: 56   LDLDAHIAVCEYNQPETSSQPEIHIPCSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLM 115
            +D   ++     + P+   +PEI +     P      F  ++     L+N+T S  N+  
Sbjct: 1822 IDYKKNVRQVTSSTPKADGKPEISLLHGISPVATTNEFPDRNRTPSDLDNNTPSSRNVPD 1881

Query: 116  NAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQTSS 155
            N  S M  N + SN +     Q   +    P     ++SS
Sbjct: 1882 NGASLMTGNAERSNCSRSPTRQVDRSPNSRPGSAAERSSS 1921


>UniRef50_A2EZQ0 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 2525

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 32/135 (23%), Positives = 57/135 (42%), Gaps = 12/135 (8%)

Query: 101 QHLNNDTQSHMNLLMNAYSEMKINNDMSNANMDTKEQEAMALWDAPDKDGNQTSSPPLNN 160
           Q  + D     ++ +N +S  KI ND    N+  K    + + D PD D  + S+     
Sbjct: 584 QDKSQDLYDFYDVFLNNFSA-KIGNDGLTENLSVKTVVGLPIIDLPDLDSIKISTEIPEI 642

Query: 161 TSALIRALYERVVVLEQRNREQDIVIANISKQLSAFAVAKMKQNNEMLLRYC-------M 213
           T  L +  Y   + + +     D   ++ +++       +  +  EMLL+ C        
Sbjct: 643 TVNLSKQNYLDFISIFKPLTNLDFEKSDKNQKTK----TEKSKTFEMLLKKCNIKVDNEQ 698

Query: 214 GNYVWRIDNFKTRLD 228
            NYV+ +DNFK + D
Sbjct: 699 NNYVFVLDNFKAKSD 713


>UniRef50_P42527 Cluster: Myosin heavy chain kinase A; n=2;
           Dictyostelium discoideum|Rep: Myosin heavy chain kinase
           A - Dictyostelium discoideum (Slime mold)
          Length = 1146

 Score = 33.5 bits (73), Expect = 8.7
 Identities = 13/37 (35%), Positives = 19/37 (51%)

Query: 82  CSFKPAGCKETFDSQDEMNQHLNNDTQSHMNLLMNAY 118
           C FK  GC     S+ E + HL +D Q H+ L +  +
Sbjct: 48  CPFKKFGCSSFLVSKAEFDNHLKDDAQFHLQLAVEKF 84


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.320    0.133    0.403 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 408,866,544
Number of Sequences: 1657284
Number of extensions: 17295919
Number of successful extensions: 54975
Number of sequences better than 10.0: 126
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 54633
Number of HSP's gapped (non-prelim): 309
length of query: 359
length of database: 575,637,011
effective HSP length: 102
effective length of query: 257
effective length of database: 406,594,043
effective search space: 104494669051
effective search space used: 104494669051
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 73 (33.5 bits)

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