Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001278-TA|BGIBMGA001278-PA|IPR001365|Adenosine/AMP
deaminase
(303 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000DB6DD1 Cluster: PREDICTED: similar to Adenosine ... 235 1e-60
UniRef50_Q4V9P6 Cluster: Adenosine deaminase-like protein; n=8; ... 209 8e-53
UniRef50_UPI00015B5D3B Cluster: PREDICTED: similar to adenosine ... 208 2e-52
UniRef50_Q9VHH7 Cluster: Adenosine deaminase-like protein; n=2; ... 206 7e-52
UniRef50_Q6DHV7 Cluster: Adenosine deaminase-like protein; n=23;... 198 1e-49
UniRef50_UPI0000D56A81 Cluster: PREDICTED: similar to CG11994-PA... 184 3e-45
UniRef50_Q16EF1 Cluster: Adenosine deaminase; n=3; Culicidae|Rep... 175 1e-42
UniRef50_Q8LPL7 Cluster: Putative adenosine deaminase; n=5; Magn... 159 6e-38
UniRef50_A4RZ27 Cluster: Predicted protein; n=2; Ostreococcus|Re... 138 1e-31
UniRef50_Q8IG39 Cluster: Adenosine deaminase-like protein; n=1; ... 138 1e-31
UniRef50_Q4PH49 Cluster: Putative uncharacterized protein; n=1; ... 136 9e-31
UniRef50_UPI00006CFBAF Cluster: Adenosine/AMP deaminase family p... 127 4e-28
UniRef50_UPI0000E47053 Cluster: PREDICTED: hypothetical protein;... 125 2e-27
UniRef50_A0BIN4 Cluster: Chromosome undetermined scaffold_11, wh... 121 2e-26
UniRef50_UPI0000499172 Cluster: adenosine deaminase; n=1; Entamo... 117 3e-25
UniRef50_Q6M9I7 Cluster: Related to adenosine deaminase; n=12; P... 117 4e-25
UniRef50_Q9ZS86 Cluster: T4B21.20 protein; n=2; Arabidopsis thal... 111 2e-23
UniRef50_A2QRJ6 Cluster: Catalytic activity: Adenosine + H(2)O <... 109 1e-22
UniRef50_Q01Q25 Cluster: Adenosine deaminase; n=1; Solibacter us... 99 2e-19
UniRef50_Q3E0Q9 Cluster: Adenosine deaminase; n=1; Chloroflexus ... 94 3e-18
UniRef50_Q7VNV1 Cluster: Adenosine deaminase; n=1; Haemophilus d... 93 8e-18
UniRef50_Q6MHR4 Cluster: Add protein; n=1; Bdellovibrio bacterio... 92 2e-17
UniRef50_O86737 Cluster: Probable adenosine deaminase 1; n=3; Ac... 92 2e-17
UniRef50_Q5LPC1 Cluster: Adenosine deaminase; n=15; Rhodobactera... 91 2e-17
UniRef50_Q03TM8 Cluster: Adenosine deaminase; n=1; Lactobacillus... 90 6e-17
UniRef50_Q839J4 Cluster: Adenosine deaminase; n=1; Enterococcus ... 90 6e-17
UniRef50_Q6A5I4 Cluster: Adenosine deaminase; n=1; Propionibacte... 89 1e-16
UniRef50_Q8D6Q8 Cluster: Adenosine deaminase; n=13; Bacteria|Rep... 89 1e-16
UniRef50_UPI0000499E34 Cluster: adenosine deaminase; n=1; Entamo... 88 3e-16
UniRef50_Q98GV2 Cluster: Adenosine deaminase; n=9; Alphaproteoba... 88 3e-16
UniRef50_Q97EV1 Cluster: Adenosine deaminase; n=2; Clostridium|R... 87 7e-16
UniRef50_Q9KNI7 Cluster: Adenosine deaminase; n=81; Gammaproteob... 85 2e-15
UniRef50_Q1IVQ0 Cluster: Adenosine deaminase; n=1; Acidobacteria... 83 9e-15
UniRef50_Q5FIX0 Cluster: Adenosine deaminase; n=6; Lactobacillus... 83 1e-14
UniRef50_A6BDK9 Cluster: Putative uncharacterized protein; n=2; ... 81 3e-14
UniRef50_Q8XHH8 Cluster: Adenosine deaminase; n=8; Bacteria|Rep:... 81 3e-14
UniRef50_Q9CIR9 Cluster: Adenosine deaminase; n=3; Lactococcus l... 81 3e-14
UniRef50_A6FY15 Cluster: Adenosine deaminase; n=1; Plesiocystis ... 81 5e-14
UniRef50_Q1N1B2 Cluster: Adenosine deaminase; n=5; Proteobacteri... 79 2e-13
UniRef50_A5UX82 Cluster: Adenosine deaminase; n=5; Chloroflexi (... 78 3e-13
UniRef50_Q8DTN8 Cluster: Adenosine deaminase; n=16; Lactobacilla... 78 3e-13
UniRef50_Q5BFL8 Cluster: Putative uncharacterized protein; n=1; ... 76 1e-12
UniRef50_Q5QWC8 Cluster: Adenosine deaminase; n=2; Idiomarina|Re... 75 2e-12
UniRef50_Q8KNI1 Cluster: CalS5; n=1; Micromonospora echinospora|... 75 2e-12
UniRef50_Q8EZR9 Cluster: Adenosine deaminase; n=4; Leptospira|Re... 75 2e-12
UniRef50_Q3WB85 Cluster: Adenosine deaminase; n=5; Actinomycetal... 75 2e-12
UniRef50_A0Q5S2 Cluster: Deoxyadenosine deaminase/adenosine deam... 75 3e-12
UniRef50_A1K1Z8 Cluster: Adenosine deaminase; n=2; Bacteria|Rep:... 74 4e-12
UniRef50_A2EQP3 Cluster: Adenosine deaminase family protein; n=2... 74 4e-12
UniRef50_A5IGY4 Cluster: Adenosine deaminase; n=4; Legionella pn... 73 9e-12
UniRef50_Q49UM8 Cluster: Putative adenosine deaminase; n=1; Stap... 73 1e-11
UniRef50_Q2S4S0 Cluster: Adenosine deaminase; n=1; Salinibacter ... 72 2e-11
UniRef50_A7H6H4 Cluster: Adenosine deaminase; n=5; Myxococcales|... 71 3e-11
UniRef50_A4FFR1 Cluster: Adenosine deaminase; n=1; Saccharopolys... 71 3e-11
UniRef50_A0FN94 Cluster: Adenosine deaminase; n=1; Burkholderia ... 71 4e-11
UniRef50_A7AW03 Cluster: Adenosine deaminase, putative; n=1; Bab... 69 1e-10
UniRef50_A7RSR8 Cluster: Predicted protein; n=1; Nematostella ve... 69 2e-10
UniRef50_Q15TP8 Cluster: Adenosine deaminase; n=2; Gammaproteoba... 67 5e-10
UniRef50_P63908 Cluster: Adenosine deaminase; n=38; Actinobacter... 67 6e-10
UniRef50_UPI0000E4677B Cluster: PREDICTED: similar to Adenosine ... 66 8e-10
UniRef50_Q1A7N0 Cluster: Adenosine deaminase; n=3; Schistosoma j... 66 1e-09
UniRef50_UPI000058758F Cluster: PREDICTED: similar to Adenosine ... 65 2e-09
UniRef50_Q54KF3 Cluster: Adenosine deaminase; n=1; Dictyostelium... 65 2e-09
UniRef50_P53984 Cluster: Adenosine deaminase; n=9; Bacteria|Rep:... 65 2e-09
UniRef50_Q2JFM4 Cluster: Adenosine deaminase; n=3; Frankia|Rep: ... 65 2e-09
UniRef50_Q20YN2 Cluster: Adenosine deaminase; n=2; Proteobacteri... 64 3e-09
UniRef50_Q86GS5 Cluster: Adenosine deaminase; n=9; Plasmodium|Re... 64 4e-09
UniRef50_A7SPK9 Cluster: Predicted protein; n=1; Nematostella ve... 64 6e-09
UniRef50_Q2JC46 Cluster: Adenosine deaminase; n=1; Frankia sp. C... 62 2e-08
UniRef50_Q6IWY7 Cluster: Adenosine deaminase; n=1; Trichinella s... 62 2e-08
UniRef50_UPI00006A2D02 Cluster: UPI00006A2D02 related cluster; n... 62 2e-08
UniRef50_Q4CZU3 Cluster: Putative uncharacterized protein; n=2; ... 61 3e-08
UniRef50_Q6F1Q1 Cluster: Adenosine deaminase; n=1; Mesoplasma fl... 61 4e-08
UniRef50_P00813 Cluster: Adenosine deaminase; n=32; Euteleostomi... 60 7e-08
UniRef50_Q8XXL5 Cluster: Adenosine deaminase; n=104; Bacteria|Re... 58 2e-07
UniRef50_Q0VNC2 Cluster: Putative uncharacterized protein; n=1; ... 58 4e-07
UniRef50_Q64PK0 Cluster: Putative adenosine deaminase; n=1; Bact... 57 5e-07
UniRef50_Q4QHD0 Cluster: Putative uncharacterized protein; n=3; ... 57 5e-07
UniRef50_Q9X7T2 Cluster: Probable adenosine deaminase 2; n=5; Ac... 57 6e-07
UniRef50_UPI0000D558D4 Cluster: PREDICTED: similar to CG5992-PA,... 56 9e-07
UniRef50_Q1FNG4 Cluster: Adenosine deaminase; n=1; Clostridium p... 56 9e-07
UniRef50_Q2J4I8 Cluster: Adenosine deaminase; n=3; Frankineae|Re... 56 1e-06
UniRef50_A0LRH8 Cluster: Adenosine deaminase; n=1; Acidothermus ... 56 1e-06
UniRef50_UPI0000D558D5 Cluster: PREDICTED: similar to Cat eye sy... 55 3e-06
UniRef50_UPI00006601DD Cluster: Adenosine deaminase (EC 3.5.4.4)... 54 3e-06
UniRef50_Q0YRQ4 Cluster: Adenosine/AMP deaminase precursor; n=1;... 54 3e-06
UniRef50_Q57W08 Cluster: Putative uncharacterized protein; n=1; ... 54 5e-06
UniRef50_Q2H9J1 Cluster: Putative uncharacterized protein; n=1; ... 54 5e-06
UniRef50_UPI000038CB1B Cluster: COG1816: Adenosine deaminase; n=... 54 6e-06
UniRef50_Q17747 Cluster: Putative uncharacterized protein; n=3; ... 54 6e-06
UniRef50_Q2JAE3 Cluster: Adenosine/AMP deaminase; n=1; Frankia s... 53 1e-05
UniRef50_Q9NZK5 Cluster: Cat eye syndrome critical region protei... 53 1e-05
UniRef50_A7HDC2 Cluster: Adenosine deaminase; n=3; Myxococcaceae... 52 1e-05
UniRef50_A5IHA0 Cluster: Adenosine deaminase; n=4; Legionella pn... 52 2e-05
UniRef50_Q1YXC1 Cluster: Adenosine deaminase; n=1; Photobacteriu... 52 2e-05
UniRef50_Q2FRB2 Cluster: Adenosine/AMP deaminase; n=1; Methanosp... 51 3e-05
UniRef50_UPI000023D260 Cluster: hypothetical protein FG06422.1; ... 51 4e-05
UniRef50_O83085 Cluster: Adenosine deaminase; n=2; Treponema|Rep... 50 6e-05
UniRef50_A6WE69 Cluster: Adenosine deaminase; n=1; Kineococcus r... 50 7e-05
UniRef50_Q7N3E5 Cluster: Similar to adenosine deaminase; n=1; Ph... 50 1e-04
UniRef50_A3VU86 Cluster: Adenosine deaminase; n=1; Parvularcula ... 50 1e-04
UniRef50_A0JTD4 Cluster: Adenosine deaminase; n=2; Bacteria|Rep:... 50 1e-04
UniRef50_A6W9Q9 Cluster: Adenosine deaminase; n=1; Kineococcus r... 49 1e-04
UniRef50_A4ADQ6 Cluster: Adenosine deaminase; n=1; Congregibacte... 49 1e-04
UniRef50_Q0RQP4 Cluster: Putative adenosine deaminase 3; n=1; Fr... 48 2e-04
UniRef50_Q4FWQ3 Cluster: Adenosine deaminase, putative; n=4; Lei... 48 2e-04
UniRef50_A6M8U8 Cluster: Adenosine deaminase-related growth fact... 48 2e-04
UniRef50_A1CUF8 Cluster: CECR1 family adenosine deaminase, putat... 48 4e-04
UniRef50_Q5NPT1 Cluster: Adenosine deaminase; n=1; Zymomonas mob... 47 5e-04
UniRef50_Q14HR2 Cluster: Adenosine deaminase; n=7; Francisella t... 47 5e-04
UniRef50_A3H9U3 Cluster: Adenosine deaminase; n=1; Caldivirga ma... 47 5e-04
UniRef50_Q4UZY3 Cluster: Adenosine deaminase; n=6; Xanthomonas|R... 46 0.001
UniRef50_Q096I6 Cluster: Adenosine deaminase; n=1; Stigmatella a... 46 0.001
UniRef50_A5FE69 Cluster: Adenosine/AMP deaminase precursor; n=1;... 46 0.001
UniRef50_Q553U5 Cluster: Adenosine deaminase-related growth fact... 46 0.001
UniRef50_Q9P6J8 Cluster: Adenine deaminase; n=1; Schizosaccharom... 45 0.002
UniRef50_Q9P6I7 Cluster: Adenosine deaminase; n=12; Ascomycota|R... 45 0.002
UniRef50_A4REQ3 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003
UniRef50_UPI00015B4087 Cluster: PREDICTED: similar to CG5992-PA;... 44 0.004
UniRef50_Q5FR10 Cluster: Adenosine deaminase; n=2; Alphaproteoba... 44 0.004
UniRef50_UPI0000DB7737 Cluster: PREDICTED: similar to Adenosine ... 44 0.005
UniRef50_Q1IM40 Cluster: Adenosine/AMP deaminase precursor; n=1;... 44 0.005
UniRef50_UPI00015B4088 Cluster: PREDICTED: similar to adenosine ... 43 0.009
UniRef50_A4B200 Cluster: Adenosine deaminase; n=1; Alteromonas m... 43 0.009
UniRef50_UPI0000DAE38A Cluster: hypothetical protein Rgryl_01000... 43 0.011
UniRef50_Q9VFS0 Cluster: CG9345-PA; n=1; Drosophila melanogaster... 43 0.011
UniRef50_Q179D4 Cluster: Adenosine deaminase; n=6; Culicidae|Rep... 43 0.011
UniRef50_Q7QI64 Cluster: ENSANGP00000003634; n=1; Anopheles gamb... 42 0.015
UniRef50_A0CG01 Cluster: Chromosome undetermined scaffold_178, w... 42 0.015
UniRef50_Q4IMJ1 Cluster: Adenosine deaminase; n=1; Gibberella ze... 42 0.015
UniRef50_Q6ALG5 Cluster: Related to adenosine deaminase; n=2; Ba... 42 0.020
UniRef50_P15274 Cluster: AMP deaminase; n=13; Saccharomycetales|... 42 0.020
UniRef50_Q291C7 Cluster: GA10106-PA; n=2; Diptera|Rep: GA10106-P... 41 0.034
UniRef50_A6SNR0 Cluster: Putative uncharacterized protein; n=1; ... 41 0.034
UniRef50_Q8YNZ1 Cluster: All4418 protein; n=14; Cyanobacteria|Re... 41 0.045
UniRef50_Q22E33 Cluster: Adenosine/AMP deaminase family protein;... 41 0.045
UniRef50_Q9U7C6 Cluster: Salivary gland growth factor-1 precurso... 40 0.060
UniRef50_Q2GSL1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.060
UniRef50_A6S7C8 Cluster: Putative uncharacterized protein; n=2; ... 40 0.060
UniRef50_A4ZQ11 Cluster: Adenyl deaminase; n=1; Dekkera bruxelle... 40 0.060
UniRef50_A1D5P4 Cluster: Adenosine deaminase family protein; n=5... 40 0.060
UniRef50_Q9VFS1 Cluster: CG9621-PA; n=2; Sophophora|Rep: CG9621-... 40 0.079
UniRef50_A0E0U4 Cluster: Chromosome undetermined scaffold_72, wh... 40 0.10
UniRef50_Q0UD18 Cluster: Putative uncharacterized protein; n=1; ... 40 0.10
UniRef50_A5K7U3 Cluster: Adenosine/AMP deaminase, putative; n=6;... 39 0.14
UniRef50_Q95WT8 Cluster: Salivary adenosine deaminase; n=2; Culi... 39 0.18
UniRef50_Q7KGG1 Cluster: Adenosine deaminase-related growth fact... 38 0.24
UniRef50_Q7SGM7 Cluster: Putative uncharacterized protein NCU080... 38 0.24
UniRef50_Q8PYN8 Cluster: Conserved protein; n=4; Methanosarcinac... 38 0.24
UniRef50_Q4S691 Cluster: Chromosome 9 SCAF14729, whole genome sh... 38 0.32
UniRef50_Q38ZJ2 Cluster: Adenosine deaminase; n=3; Bacteria|Rep:... 38 0.32
UniRef50_A6R6E4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.32
UniRef50_A6L6P5 Cluster: Putative uncharacterized protein; n=1; ... 38 0.42
UniRef50_P50998 Cluster: AMP deaminase; n=1; Schizosaccharomyces... 38 0.42
UniRef50_A3U074 Cluster: Adenosine deaminase; n=1; Oceanicola ba... 37 0.56
UniRef50_Q8NIZ8 Cluster: Related to cecr1 protein; n=6; Pezizomy... 37 0.56
UniRef50_Q5UWY8 Cluster: Chlorohydrolase family protein; n=1; Ha... 37 0.56
UniRef50_Q8EZ87 Cluster: Adenosine deaminase; n=4; Leptospira|Re... 37 0.74
UniRef50_Q80SY6-3 Cluster: Isoform 3 of Q80SY6 ; n=2; Eutheria|R... 36 0.98
UniRef50_A7IPF6 Cluster: Adenosine/AMP deaminase precursor; n=1;... 36 1.3
UniRef50_Q0SBH5 Cluster: Arylsulfatase; n=1; Rhodococcus sp. RHA... 36 1.7
UniRef50_A6RK08 Cluster: Putative uncharacterized protein; n=1; ... 36 1.7
UniRef50_A3IDU1 Cluster: Putative 5'-3' exonuclease; n... 35 3.0
UniRef50_Q9VVK5 Cluster: CG5992-PA, isoform A; n=6; Schizophora|... 35 3.0
UniRef50_A7ER99 Cluster: Putative uncharacterized protein; n=1; ... 35 3.0
UniRef50_A7E4Y0 Cluster: Putative uncharacterized protein; n=1; ... 35 3.0
UniRef50_Q3M5Z5 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.9
UniRef50_Q1YG22 Cluster: Alpha-amylase family protein; n=3; Rhiz... 34 3.9
UniRef50_A0R7F0 Cluster: Amidohydrolase family protein; n=2; Act... 34 3.9
UniRef50_Q22TE2 Cluster: Adenosine/AMP deaminase family protein;... 34 3.9
UniRef50_UPI000155C584 Cluster: PREDICTED: similar to helicase B... 34 5.2
UniRef50_Q22YL6 Cluster: Putative uncharacterized protein; n=1; ... 34 5.2
UniRef50_A7AV25 Cluster: JmjC transcription factor, putative; n=... 34 5.2
UniRef50_A1Z9F9 Cluster: CG13335-PA, isoform A; n=5; Sophophora|... 34 5.2
UniRef50_Q59GS5 Cluster: Paxillin variant; n=6; Eutheria|Rep: Pa... 34 5.2
UniRef50_A6PKL2 Cluster: Glycyl-radical enzyme activating protei... 33 6.9
UniRef50_A3ZY64 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_A4RGE3 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_P53909 Cluster: Adenosine deaminase; n=10; Saccharomyce... 33 6.9
UniRef50_UPI0000E48CF5 Cluster: PREDICTED: similar to mollusk-de... 33 9.1
UniRef50_Q4DEV2 Cluster: Putative uncharacterized protein; n=2; ... 33 9.1
UniRef50_A2DM60 Cluster: Ankyrin repeat protein, putative; n=1; ... 33 9.1
>UniRef50_UPI0000DB6DD1 Cluster: PREDICTED: similar to Adenosine
deaminase CG11994-PA; n=1; Apis mellifera|Rep:
PREDICTED: similar to Adenosine deaminase CG11994-PA -
Apis mellifera
Length = 340
Score = 235 bits (574), Expect = 1e-60
Identities = 122/281 (43%), Positives = 174/281 (61%), Gaps = 22/281 (7%)
Query: 30 DTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDT-QYITKK 88
D L+ECF+VF I H LT T EA+ AT T++EFQ+D Y+ELRSTPR + ++K+
Sbjct: 51 DFSTLNECFKVFDIIHLLTVTPEAIFHATYNTIKEFQDDNVIYLELRSTPRAIPEKMSKQ 110
Query: 89 QYIDSIIRAMEASQL-------------------QEVEEIADIAIERHKIHPDTVVGIEL 129
+Y+++II+A E ++ + +E ++AI K +P +VG++L
Sbjct: 111 EYVEAIIKAFEVCKIDFPNILVKLLISVNRKQGYKAAQENIELAINFMKKYPQYIVGLDL 170
Query: 130 SGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKY 189
SG+P G+ F+ L +AR +GLK+ HC EV N E +++L FKP+R+GH C+HP
Sbjct: 171 SGDPMTGSI--FLKLLKKARMAGLKIAAHCAEVSNETEAIDILEFKPDRLGHCTCVHPTL 228
Query: 190 GGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFAT 249
GT + + L SKIPVE+CLTSNV K P YESH FK L E G + L TDDKGVF T
Sbjct: 229 QGTNKLFNLLINSKIPVELCLTSNVRCKTVPTYESHQFKYLFEVGHPICLSTDDKGVFHT 288
Query: 250 SLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELI 290
SLSQEY++ + +F L+R Q+ KL L + Q F + +EL+
Sbjct: 289 SLSQEYKIASSTFNLSREQLIKLCLSSVQYAFVTSEEKELL 329
>UniRef50_Q4V9P6 Cluster: Adenosine deaminase-like protein; n=8;
Euteleostomi|Rep: Adenosine deaminase-like protein -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 348
Score = 209 bits (510), Expect = 8e-53
Identities = 114/285 (40%), Positives = 167/285 (58%), Gaps = 22/285 (7%)
Query: 26 IGAGDTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQY- 84
I G R L ECFQVF + H L + E ++M + +QEF DG Y+ELRSTPR+
Sbjct: 49 IRRGQRRTLDECFQVFKVIHQLVDSEEDILMVAKSVIQEFAADGVKYLELRSTPREVTET 108
Query: 85 -ITKKQYIDSIIRAMEASQLQEVEE-----IA-------DIAIERHKIHPD-------TV 124
++K++YI++++ A+ + + V+ +A ++A++ K+ D TV
Sbjct: 109 GLSKQRYIETVLEAIRQCKQEGVDIDVRFLVAVDRRHGPEVAMQTVKLAEDFLLSSDGTV 168
Query: 125 VGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEML-NFKPERIGHGV 183
VG++LSG+P VG+ D + AL +A+ GLK+ LH EV + + E+L N P+RIGHG
Sbjct: 169 VGLDLSGDPTVGHGKDLLAALQKAKNCGLKLALHLSEVPSQIDETELLLNLPPDRIGHGT 228
Query: 184 CIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDD 243
+HP GG++ +C+ IP+E+CLTSNV + P Y+ HHFK G VLCTDD
Sbjct: 229 FLHPDVGGSDSLVDKVCKQNIPIEICLTSNVKGQTVPSYDKHHFKYWYNRGHPCVLCTDD 288
Query: 244 KGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRE 288
KGVF T LSQEY+L A +F LT+ V LS A F+ I++
Sbjct: 289 KGVFCTDLSQEYQLAASTFGLTKEAVWILSQQAIGYTFAPEPIKQ 333
>UniRef50_UPI00015B5D3B Cluster: PREDICTED: similar to adenosine
deaminase-like; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to adenosine deaminase-like - Nasonia
vitripennis
Length = 363
Score = 208 bits (507), Expect = 2e-52
Identities = 116/279 (41%), Positives = 170/279 (60%), Gaps = 31/279 (11%)
Query: 32 RNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITKKQYI 91
++L+E F+VFS A+S+T+T EA+ AT T++EF +D Y+ELRSTPR +TKK+YI
Sbjct: 64 KSLTEIFEVFSFAYSVTTTPEAIYTATYDTIREFHDDNVIYLELRSTPRAENGMTKKEYI 123
Query: 92 DSIIRAMEASQLQEV-------------------EEIADIAIERHKIHPDTVVGIELSGN 132
+I+RA+E+ +++ + +E +AIE K + + +VGI+LSG+
Sbjct: 124 LAILRAIESCKMEGLIITVKLLISVNRKQGFKAAKENIHLAIEMSKEY-ENIVGIDLSGD 182
Query: 133 PAVGNFGDFIPALNRARQSGLKVTLHCGEV---------CNPEEVLEMLNFKPERIGHGV 183
P G+ FI L++AR++GL++ HC EV N E +++L FKPER+GHG
Sbjct: 183 PTKGDA--FIELLSQARKAGLRIAAHCAEVPNYLIHYTYANEVETMDILKFKPERLGHGT 240
Query: 184 CIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDD 243
CIHP GTE+ + AL SKIPVE+CLTSNV K Y+ HHFK L ++ + +CTDD
Sbjct: 241 CIHPSTNGTEKLYQALLDSKIPVELCLTSNVKCKTVMTYDEHHFKYLNDSKHPICICTDD 300
Query: 244 KGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFS 282
KGVF T+LS+E +L A+ F L + L F+
Sbjct: 301 KGVFDTTLSKELQLAAKYFNLNNEDLVTLMKSTVDYTFA 339
>UniRef50_Q9VHH7 Cluster: Adenosine deaminase-like protein; n=2;
Sophophora|Rep: Adenosine deaminase-like protein -
Drosophila melanogaster (Fruit fly)
Length = 337
Score = 206 bits (502), Expect = 7e-52
Identities = 106/270 (39%), Positives = 156/270 (57%), Gaps = 25/270 (9%)
Query: 32 RNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITKKQYI 91
+++ CF+ F+ H LTST E L ATEL +++F ED Y+E+R+TP+ + +++ Y+
Sbjct: 53 KDMDACFEKFAFVHELTSTREGLRFATELAIRDFAEDNVQYVEMRTTPKANENYSRRDYL 112
Query: 92 DSIIRAMEASQ-------------------LQEVEEIADIAIERHKIHPDTVVGIELSGN 132
+I A++A+ + EE +A+E + HP+ ++GI+LSGN
Sbjct: 113 QIVIDAIKAASETYPEITVKLLPSINRAEPVDVAEETVSLAVELARAHPNLILGIDLSGN 172
Query: 133 PAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGT 192
P G F DF P L +AR GLK+ +HC E+ NP EV EML+F R GHG + P+ G
Sbjct: 173 PGKGRFSDFAPILAQARDKGLKLAIHCAEIENPSEVKEMLHFGMSRCGHGTFLTPEDIG- 231
Query: 193 EETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLS 252
L Q I +E CLTSNV + P E HH K ++EA V+CTDD GVF T+L+
Sbjct: 232 -----QLKQRNIAIECCLTSNVKSGTVPSLEEHHLKRIMEADAPKVICTDDSGVFDTTLT 286
Query: 253 QEYRLCAESFALTRIQVAKLSLDAAQCIFS 282
+E+ + AE+F LTR Q L+L+A F+
Sbjct: 287 KEFLIAAETFGLTREQCIDLTLEAVHHSFA 316
>UniRef50_Q6DHV7 Cluster: Adenosine deaminase-like protein; n=23;
Tetrapoda|Rep: Adenosine deaminase-like protein - Homo
sapiens (Human)
Length = 355
Score = 198 bits (483), Expect = 1e-49
Identities = 111/284 (39%), Positives = 167/284 (58%), Gaps = 22/284 (7%)
Query: 26 IGAGDTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPR--DTQ 83
I G R L ECFQ+F H LTS+ E ++M T+ ++EF +DG Y+ELRSTPR +
Sbjct: 55 IDKGKKRTLEECFQMFQTIHQLTSSPEDILMVTKDVIKEFADDGVKYLELRSTPRRENAT 114
Query: 84 YITKKQYIDSIIRAMEASQLQEVE-------------------EIADIAIERHKIHPDTV 124
+TKK Y++SI+ ++ S+ + ++ E +A E TV
Sbjct: 115 GMTKKTYVESILEGIKQSKQENLDIDVRYLIAVDRRGGPLVAKETVKLAEEFFLSTEGTV 174
Query: 125 VGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLE-MLNFKPERIGHGV 183
+G++LSG+P VG DF+ L A+++GLK+ LH E+ N ++ + +L+ P+RIGHG
Sbjct: 175 LGLDLSGDPTVGQAKDFLEPLLEAKKAGLKLALHLSEIPNQKKETQILLDLLPDRIGHGT 234
Query: 184 CIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDD 243
++ GG+ + + Q +IP+E+CLTSNV ++ P Y+ HHF V+CTDD
Sbjct: 235 FLNSGEGGSLDLVDFVRQHRIPLELCLTSNVKSQTVPSYDQHHFGFWYSIAHPSVICTDD 294
Query: 244 KGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIR 287
KGVFAT LSQEY+L AE+F LT+ QV LS ++ IF+ + R
Sbjct: 295 KGVFATHLSQEYQLAAETFNLTQSQVWDLSYESINYIFASDSTR 338
>UniRef50_UPI0000D56A81 Cluster: PREDICTED: similar to CG11994-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG11994-PA - Tribolium castaneum
Length = 334
Score = 184 bits (447), Expect = 3e-45
Identities = 97/268 (36%), Positives = 154/268 (57%), Gaps = 23/268 (8%)
Query: 32 RNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITKKQYI 91
+ L+ECF++F +AH+ T +A+ +AT+ +++F D Y+ELR+TPR+ + +++ +YI
Sbjct: 52 KTLNECFKLFKVAHNATKNPQAVYLATKYVIEDFYNDNVAYLELRTTPREEENMSRVEYI 111
Query: 92 DSIIRAME---------------ASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVG 136
+S+++A+E S +VEE ++ I+ + +P + G++ SGNP VG
Sbjct: 112 ESVVKAIEDCDKKIIVKLLLSIDRSNNLKVEENMEVIIKMKEKYPHVIKGVDFSGNPYVG 171
Query: 137 NFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETW 196
F + +AR SGL VTLHC E+ N +EV E+L F+P+RIGHG + + W
Sbjct: 172 GFNPKL--FQKARDSGLFVTLHCAEIKNDKEVEEILKFRPDRIGHGTFLL----SNDHIW 225
Query: 197 IALCQSKIPV--EVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQE 254
+ IP+ E CLTSNV T Y+ HH +E I+ L LCTDDKGVF T+LS+E
Sbjct: 226 KLYLDTNIPLVSECCLTSNVACGTTKSYKEHHLQEWIKNSLPFTLCTDDKGVFGTTLSKE 285
Query: 255 YRLCAESFALTRIQVAKLSLDAAQCIFS 282
L + F+L + ++L F+
Sbjct: 286 LVLACQYFSLKPTDLWDMTLKTISYTFA 313
>UniRef50_Q16EF1 Cluster: Adenosine deaminase; n=3; Culicidae|Rep:
Adenosine deaminase - Aedes aegypti (Yellowfever
mosquito)
Length = 347
Score = 175 bits (426), Expect = 1e-42
Identities = 100/270 (37%), Positives = 146/270 (54%), Gaps = 25/270 (9%)
Query: 22 DEFQIGAGDTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRD 81
D ++I G L ECFQ F+ AH LT + L AT+ ++EF ED Y+ELR+TP+
Sbjct: 48 DFYKITGGQNLTLKECFQKFTYAHQLTDHPKTLAYATKAVIREFAEDNVIYLELRTTPKS 107
Query: 82 TQYITKKQYIDSIIRAM-EASQ------------------LQEVEEIADIAIERHKIHPD 122
T +TK+QY+ +++ A+ +AS+ + E EE + +E D
Sbjct: 108 TTNMTKRQYLTTVLEAIRQASEELPSIVVKLLPSIDRSKGVLEAEENVALVLELLPAFSD 167
Query: 123 TVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHG 182
+VG++LSG P F D+ + RA+ +GL++ LHCGE + EV EM F +RIGHG
Sbjct: 168 IIVGMDLSGAPYKTKFSDYARLMKRAQAAGLRMALHCGEFDDDGEVQEMFEFGTDRIGHG 227
Query: 183 VCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTD 242
I G + + +IP E CLTSN+ Y+ HHF L E G V + TD
Sbjct: 228 TFIR----GDNLQFAK--ERRIPFECCLTSNIKCSTVGSYKEHHFGRLWEGGFDVCINTD 281
Query: 243 DKGVFATSLSQEYRLCAESFALTRIQVAKL 272
D GVF TSLSQE ++C++ F L++ + L
Sbjct: 282 DFGVFDTSLSQELQICSKVFGLSQEDIITL 311
>UniRef50_Q8LPL7 Cluster: Putative adenosine deaminase; n=5;
Magnoliophyta|Rep: Putative adenosine deaminase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 355
Score = 159 bits (387), Expect = 6e-38
Identities = 83/202 (41%), Positives = 116/202 (57%), Gaps = 9/202 (4%)
Query: 87 KKQYIDSIIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALN 146
KK Y+ ++ + E +A+E + VVGI+LSGNP VG + F+PAL
Sbjct: 149 KKIYVRLLLSIDRRETTESAMETVKLALEMRDVG---VVGIDLSGNPLVGEWSTFLPALQ 205
Query: 147 RARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPV 206
A+ + L +TLHCGEV NP+E+ ML+FKP RIGH C +E W L +IPV
Sbjct: 206 YAKDNDLHITLHCGEVPNPKEIQAMLDFKPHRIGHA-CFFK-----DEDWTKLKSFRIPV 259
Query: 207 EVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTR 266
E+CLTSN+ TK + HHF +L A ++LCTDD GVF+TSLS EY L S L++
Sbjct: 260 EICLTSNIVTKSISSIDIHHFADLYNAKHPLILCTDDFGVFSTSLSNEYALAVRSLGLSK 319
Query: 267 IQVAKLSLDAAQCIFSEANIRE 288
+ L+ A F+E +++
Sbjct: 320 SETFALARAAIDATFAEDEVKQ 341
Score = 51.6 bits (118), Expect = 2e-05
Identities = 31/122 (25%), Positives = 66/122 (54%), Gaps = 8/122 (6%)
Query: 1 MLQLQRYYVDAGISDKTNTFLDEFQIGAGDTRNLSECFQVFSIAHSLTSTSEALVMATEL 60
+L+L R + G+ F D + + R+L E F++F + H LT+ + + T
Sbjct: 25 LLELARVLGEKGVI----VFADVEHVIQKNDRSLVEVFKLFDLIHKLTTDHKTVTRITRE 80
Query: 61 TLQEFQEDGCCYIELRSTPR--DTQYITKKQYIDSIIRAMEASQLQEVEEIADIAIERHK 118
+++F + Y+ELR+TP+ D+ ++K+ Y++++I+ + + + EV+ A + K
Sbjct: 81 VVEDFALENVVYLELRTTPKRSDSIGMSKRSYMEAVIQGLRS--VSEVDIDFVTASDSQK 138
Query: 119 IH 120
+H
Sbjct: 139 LH 140
>UniRef50_A4RZ27 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 311
Score = 138 bits (335), Expect = 1e-31
Identities = 91/282 (32%), Positives = 145/282 (51%), Gaps = 33/282 (11%)
Query: 32 RNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITKKQYI 91
R+L CF++F + H+ + AL T ++F DG Y+ELR+TP+ + I K++Y+
Sbjct: 37 RDLLACFEIFKLVHACVDDAAALRRVTREVCEDFARDGARYLELRTTPK--EQIGKERYV 94
Query: 92 DSIIRAME------ASQLQEVEEIADIAIERHKIHPDTV--------VGIELSGNPAVG- 136
++++ +E + E A I + + D + I+ VG
Sbjct: 95 EAVLSGLEDACGRCGGDGADGELAARIILSVDRARDDDASKAMETIDLAIKYKERGVVGV 154
Query: 137 ---------NFGDFIPALNRARQSGLKVTLHCGEVCNPE-EVLEMLNFKPERIGHGVCIH 186
++ ++ A +AR GL +LH GEV N E E + F+P+R+GH C+
Sbjct: 155 DLSGSPVVGHWDRYVAAFEKARAHGLGTSLHNGEVANTEAEQRAFIAFRPDRLGH--CV- 211
Query: 187 PKYGGTEETWIA-LCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKG 245
Y +E+ + L SKIPVE+CLTSNV T+ + HHF +L AG + LCTDD
Sbjct: 212 --YTVRDESLLRDLLASKIPVELCLTSNVKTRSCAGFAEHHFAKLRSAGHPICLCTDDTW 269
Query: 246 VFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIR 287
VF TSLS+EY + AE+F LT ++ +S A F + +++
Sbjct: 270 VFQTSLSREYAIAAETFGLTDDEIRDMSTRAMDFAFCDEDVK 311
>UniRef50_Q8IG39 Cluster: Adenosine deaminase-like protein; n=1;
Caenorhabditis elegans|Rep: Adenosine deaminase-like
protein - Caenorhabditis elegans
Length = 388
Score = 138 bits (335), Expect = 1e-31
Identities = 85/278 (30%), Positives = 150/278 (53%), Gaps = 25/278 (8%)
Query: 33 NLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITKKQYID 92
N++ F F + H++ EA+ +A T++EF+ED C Y+ELR++P++T ++T + Y+
Sbjct: 102 NMTGVFDCFPVIHAILRKPEAIRIAIRQTIKEFEEDNCVYLELRTSPKETDFMTYEDYLQ 161
Query: 93 SIIRAMEAS--QLQEVEEIADIAIERH----------------KIHPDTVVGIELSGNPA 134
I + EA+ + ++ ++++R + + +VG+ELSG+P
Sbjct: 162 VCIESFEAAKHEFPRIKTFLIVSLDRRMPFETAAHILGLIGEAQQRTNVIVGVELSGDPH 221
Query: 135 VGNFGDFIPALNRARQSGLKVTLHCGEVC-NPEEVLEMLNFKPERIGHGVCIHPKYGGTE 193
+ + R GL +T+H EV N +V + LN +P+RIGHG +H
Sbjct: 222 LDGRRLLKLFVAARRFHGLGITIHLAEVLQNMADVEDYLNLRPDRIGHGTFLHTD----P 277
Query: 194 ETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVF-ATSLS 252
T + KIP+E+CL+SNV +K T +Y + HF + G+ V +CTDDKGV +L+
Sbjct: 278 YTEYLTNKYKIPLEICLSSNVYSKTTTNYRNSHFNYWRKRGVPVFICTDDKGVIPGATLT 337
Query: 253 QEYRLCAESFALTRIQVAKLSLDAAQCIFS-EANIREL 289
+EY A +F L+ ++ ++ DA F+ + N+ +L
Sbjct: 338 EEYYKAAITFDLSTEELIGINQDALLNSFAYKYNVTDL 375
>UniRef50_Q4PH49 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 368
Score = 136 bits (328), Expect = 9e-31
Identities = 98/280 (35%), Positives = 137/280 (48%), Gaps = 39/280 (13%)
Query: 34 LSECFQVFSIAHSLTST-SEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITKKQYID 92
LSE F VF + H ST S+ +A EL Q+ + DG Y E+R+TPRD Y+
Sbjct: 60 LSEAFDVFRLIHECVSTLSDVERIAFELG-QDLERDGVVYGEIRTTPRDLDAKGWDGYVK 118
Query: 93 SIIRAMEASQLQEVEEIADI--AIER---------------HKIHPDTVVGIELSGNPAV 135
+++ E Q I + +I+R H+ VVGI+LSG+P
Sbjct: 119 AVLHGFERYTKQGGSVILKLLLSIDRAKHSADDAMAVVQLAHRYRQHAVVGIDLSGDPTK 178
Query: 136 GNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEET 195
F F+P+L+ AR GLK+TLH EV N +E +ML+F P R GH + +
Sbjct: 179 AEFSTFLPSLSYARTLGLKITLHAAEVRNDDEFSQMLHFAPHRFGHCCFV------SRSN 232
Query: 196 WIALCQSKIPVEVCLTSNVNTKITP--DYESHHF------------KELIEAGLSVVLCT 241
AL QSKIP+E+CLTSN+ + P HHF +E ++ + T
Sbjct: 233 LAALKQSKIPIELCLTSNLLSNSIPSGSLADHHFGIHYQPQDAQDAQEHVDNTTICCIST 292
Query: 242 DDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
DD GVF + LS EYRL ++F LT QV L+ + F
Sbjct: 293 DDSGVFGSPLSNEYRLVMDNFKLTESQVFDLARRTLKATF 332
>UniRef50_UPI00006CFBAF Cluster: Adenosine/AMP deaminase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Adenosine/AMP deaminase family protein - Tetrahymena
thermophila SB210
Length = 341
Score = 127 bits (306), Expect = 4e-28
Identities = 79/278 (28%), Positives = 144/278 (51%), Gaps = 29/278 (10%)
Query: 30 DTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQY--ITK 87
D RN+ F +FS+ H + + + + L++F++ Y+ELR+TP+ + TK
Sbjct: 51 DLRNIKGAFSIFSLIHQVLRDLQDIRRVSREVLEDFRDQNVAYLELRTTPKSCELGTYTK 110
Query: 88 KQYIDSIIRAMEASQLQEVEEIAD---IAIERHKIHPDT---------------VVGIEL 129
+QY++++I ++ Q Q +++ ++I+R + D +VG++
Sbjct: 111 EQYLNTVIDEIQKFQQQYGDKMQARLLVSIDRGRPLEDAQSTLNHILKLKNNNIIVGLDF 170
Query: 130 SGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPE---EVLEMLNFKPERIGHGVCIH 186
SGNP+ F ++ L +AR+ G K+T+H E+ E E +++NFKP+R+GH +
Sbjct: 171 SGNPSKSTFKEYEQLLEQARKEGFKITIHVAELEGEEYLQESFDIVNFKPDRLGHFNFYN 230
Query: 187 PKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGV 246
++ + + Q IP+E+C TSN T HHFKE G ++ L TDD V
Sbjct: 231 ------QDLYSKVRQLNIPIEMCPTSNFYTVNMKSLSEHHFKEFFYQGHTINLNTDDTCV 284
Query: 247 FATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEA 284
F T ++QE+ ++F L+ + L + ++ IF +A
Sbjct: 285 FDTDITQEHFKMIQAFNLSEDEFKSLLVRSSNMIFDQA 322
>UniRef50_UPI0000E47053 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 125 bits (301), Expect = 2e-27
Identities = 72/206 (34%), Positives = 114/206 (55%), Gaps = 25/206 (12%)
Query: 30 DTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRD--TQYITK 87
+ + ++ CFQ F + H + +A+ M T ++EF DG Y+ELRSTPRD T +TK
Sbjct: 66 ERQTMNGCFQTFKLIHRVIKDVKAVSMVTYDVIKEFASDGVKYLELRSTPRDDATNGMTK 125
Query: 88 KQYIDSIIRAMEASQ-------------------LQEVEEIADIAIERHKIHPDTVVGIE 128
+ YID++++ +E + L+E E+ +A+E ++ D VG++
Sbjct: 126 RLYIDAVMKGIELCELDGIDTIVKFLPSIDRRMSLEEAGEVVSLALE-YQASTDKCVGLD 184
Query: 129 LSGNPAVGNFGDFIPALNRARQSGLKVTLHCGE--VCNPEEVLEMLNFKPERIGHGVCIH 186
LSG+P G+ +P L RAR GLK+ +H E CN EE +L P+RIGHG C+H
Sbjct: 185 LSGDPQFGDVKALVPLLQRARNHGLKLAIHTAEHQGCN-EESRILLGIPPDRIGHGTCLH 243
Query: 187 PKYGGTEETWIALCQSKIPVEVCLTS 212
P+ GG ++ + +S IP+ V T+
Sbjct: 244 PEAGGDQDLVDTVVRSNIPIGVFSTN 269
>UniRef50_A0BIN4 Cluster: Chromosome undetermined scaffold_11, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_11,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 296
Score = 121 bits (292), Expect = 2e-26
Identities = 76/245 (31%), Positives = 133/245 (54%), Gaps = 27/245 (11%)
Query: 34 LSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITKKQYIDS 93
L +CF +F+ +SL E + + Q+F DG Y+E+R+TP+ Q + QY+++
Sbjct: 41 LEQCFILFAKINSLNLKLEDVRRMADEIFQDFYSDGVTYLEIRATPKKGQDFDQLQYLNA 100
Query: 94 IIRAMEASQLQ--------------EVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFG 139
I A+ ++L+ E ++ ++ ++++KI +VG++L G+P +G+F
Sbjct: 101 ISEAINKAKLEIKLIVAIDRAKGVDEAQKTLNL-VKKNKIQH--LVGVDLCGHPGIGHFL 157
Query: 140 DFIPALNRARQSGLKVTLHCGEVCNP-EEVLEMLNFKPERIGHGVCIHPKYGGTEETWIA 198
++ P L + R G K+T+H GE+ EE ++ F+P+RIGH + TEE
Sbjct: 158 EYKPILQKFRDLGYKITVHTGELKQQIEENNHVIEFQPDRIGHLIYF------TEEQLQK 211
Query: 199 LCQSKIPVEVCLTSNV-NTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRL 257
+ IP+EVC +SN+ T + PD H KE I G+ + +CTDD F T++++E L
Sbjct: 212 IKSLNIPIEVCFSSNLFTTNMQPD--CHPVKEFISQGIPIAICTDDTLCFNTTVTKEIEL 269
Query: 258 CAESF 262
+F
Sbjct: 270 IKTTF 274
>UniRef50_UPI0000499172 Cluster: adenosine deaminase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: adenosine deaminase -
Entamoeba histolytica HM-1:IMSS
Length = 337
Score = 117 bits (282), Expect = 3e-25
Identities = 81/288 (28%), Positives = 139/288 (48%), Gaps = 33/288 (11%)
Query: 34 LSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITKKQYIDS 93
LS CF+ F + + T++ E + + L+++ D E+R+TPR + +++ YID+
Sbjct: 53 LSNCFKAFDLIYEATNSLERIKILAMQVLEDYDNDNTIIAEIRTTPRKLEGHSQRDYIDT 112
Query: 94 IIRAME---------------------ASQLQEVEEIADIAIERHKIHPDTVVGIELSGN 132
++ A E S+L + E ++A E K P V GIELSGN
Sbjct: 113 VVNAFEDYIKQRTKTTPFYPYLILSINRSRLNDAYETIELASEYQKKTP-FVRGIELSGN 171
Query: 133 PAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGT 192
P G + + IP + A++ L VT+H GE + EE ++++ P R+GHG+ ++ K
Sbjct: 172 PFKGTWKEIIPLMEHAKELELPVTMHIGEKVDDEECVKLIECYPSRVGHGIFLNKK--AI 229
Query: 193 EETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLS 252
E + ++ I EVCLTSN+ ++ Y+ H V + DD+G+F TS+
Sbjct: 230 E----LMHENNIGCEVCLTSNMVSRSIKGYDKHPMMNKALFKGKVFISCDDRGLFRTSMV 285
Query: 253 QEYRLCAESFALTRIQVAK-----LSLDAAQCIFSEANIRELIIGKIL 295
E R +++ Q K L L+ Q F + I++ + +L
Sbjct: 286 NEMRHAIQAYCHNNEQEGKEFMKQLCLNGIQFSFLSSEIKQKLRDYVL 333
>UniRef50_Q6M9I7 Cluster: Related to adenosine deaminase; n=12;
Pezizomycotina|Rep: Related to adenosine deaminase -
Neurospora crassa
Length = 499
Score = 117 bits (281), Expect = 4e-25
Identities = 95/289 (32%), Positives = 144/289 (49%), Gaps = 34/289 (11%)
Query: 21 LDEFQIGAGDTRNLSECFQVFS-IAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTP 79
L E +G D +L F +FS + L S AL T L +F DG Y+ELR+TP
Sbjct: 201 LIEMPLGKHDY-DLKTFFPLFSSYIYHLVSDVWALRYTTLSVLSDFASDGVVYLELRTTP 259
Query: 80 RDTQY--ITKKQYIDSIIRAM---EASQLQEVEEIADIAIERHKIHPDT----------- 123
R + +TK QY+ +I+ A+ E++ ++ ++++R P+
Sbjct: 260 RAMPHAGLTKAQYVSTILSAIAEFESTTTSALKTKLILSVDRRNTLPEAYEVLALCRQFS 319
Query: 124 ----VVGIELSGNPAVGNFGDFIPALNRARQS--GLKVTLHCGEV---CNPEEVLEMLNF 174
VVGI+L G+PA G F P AR++ GL +TLH E EE+L +L++
Sbjct: 320 GQGGVVGIDLCGDPAKGPIDIFTPVFEEARRTIPGLGITLHFAEAEASGTEEELLTLLSW 379
Query: 175 KPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNT-KITPDYESHHFKELIEA 233
KP+RIGH + ++ + + + + +E+CL+ NV+ + ESHHF E +
Sbjct: 380 KPDRIGHVIHLNKRIREKVKR-----RGGMGLELCLSCNVHAGMVCGGVESHHFGEWWKV 434
Query: 234 GLS-VVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
+ VVL TDD GVF + LS EY L A+ F LTR + L IF
Sbjct: 435 EETVVVLSTDDVGVFGSPLSNEYALVAKHFGLTRADICSLVRRGIDVIF 483
>UniRef50_Q9ZS86 Cluster: T4B21.20 protein; n=2; Arabidopsis
thaliana|Rep: T4B21.20 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 275
Score = 111 bits (268), Expect = 2e-23
Identities = 54/104 (51%), Positives = 68/104 (65%), Gaps = 6/104 (5%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGV 183
VVGI+LSGNP VG + F+PAL A+ + L +TLHCGEV NP+E+ ML+FKP RIGH
Sbjct: 177 VVGIDLSGNPLVGEWSTFLPALQYAKDNDLHITLHCGEVPNPKEIQAMLDFKPHRIGH-A 235
Query: 184 CIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHF 227
C +E W L +IPVE+CLTSN+ TK + HHF
Sbjct: 236 CFF-----KDEDWTKLKSFRIPVEICLTSNIVTKSISSIDIHHF 274
>UniRef50_A2QRJ6 Cluster: Catalytic activity: Adenosine + H(2)O <=>
inosine + NH; n=2; Aspergillus|Rep: Catalytic activity:
Adenosine + H(2)O <=> inosine + NH - Aspergillus niger
Length = 356
Score = 109 bits (261), Expect = 1e-22
Identities = 85/302 (28%), Positives = 148/302 (49%), Gaps = 40/302 (13%)
Query: 33 NLSECFQVFSIA-HSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPR--DTQYITKKQ 89
+L FQ F+ + ++L + +L AT L +FQ DG Y+ELR+ PR + T+++
Sbjct: 64 SLQTFFQSFNKSIYNLVNDLASLTYATHSVLTDFQNDGVTYLELRTIPRASPSSSFTREE 123
Query: 90 YIDSIIRAM---EASQ---------------------LQEVEEIADIAIERHKIHPDTVV 125
Y+ +++ A+ +A+Q E EI D+A+ H+ +V
Sbjct: 124 YLTTVLDAISDFQANQSPSSPKMSVYLILALDRGHHTTAEALEIVDLALA-HRARG--IV 180
Query: 126 GIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEV---CNPEEVLEMLNFKPERIGHG 182
GI++ GNP G+ A +A+ +GL +T+H E+ P E+ +L F+P+R+GH
Sbjct: 181 GIDVCGNPTKGDVSVLREAFAKAKANGLGLTVHFAEMREAAKPRELETLLEFQPDRLGHV 240
Query: 183 VCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPD-YESHHFKELIEAGLSVVLCT 241
+ + EE + + + +E+C++ NV+ K+ + HHF +VLCT
Sbjct: 241 IHV------PEELKREIARRQPGLELCMSCNVHAKMFDGGFLDHHFGYWRHQDCPIVLCT 294
Query: 242 DDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKILKFMNDY 301
DD G F + +S EY L AE F LTR V + + IF ++ + + F +Y
Sbjct: 295 DDVGFFCSPVSNEYLLAAEHFQLTRADVLGICRKSYDAIFGGEKEKDRLRRLLSDFEANY 354
Query: 302 TS 303
++
Sbjct: 355 ST 356
>UniRef50_Q01Q25 Cluster: Adenosine deaminase; n=1; Solibacter
usitatus Ellin6076|Rep: Adenosine deaminase - Solibacter
usitatus (strain Ellin6076)
Length = 307
Score = 98.7 bits (235), Expect = 2e-19
Identities = 58/190 (30%), Positives = 96/190 (50%), Gaps = 7/190 (3%)
Query: 94 IIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGL 153
I+ A+ + V +A++A ER + D V+ + G+ G F A AR +GL
Sbjct: 123 ILDAVRQFGTEHVMRVAELAAERVE---DGVIAFGIGGSEERGPANQFGEAFRFARAAGL 179
Query: 154 KVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSN 213
++T H GE P+ + + L ERIGHG+ E L IP+E+C++SN
Sbjct: 180 RLTAHAGESLGPQSIWDALELGAERIGHGIAAVRD----EALMRHLRDRDIPLEICISSN 235
Query: 214 VNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLS 273
+ T + E H + L +AG+ +VL +DD +F +L++EYRL A F T ++ L+
Sbjct: 236 LVTGVVARLEDHPVRRLYDAGVPIVLNSDDPAMFRCTLTEEYRLAAAHFGFTENELEGLA 295
Query: 274 LDAAQCIFSE 283
+ + F +
Sbjct: 296 ANGFRYAFGK 305
>UniRef50_Q3E0Q9 Cluster: Adenosine deaminase; n=1; Chloroflexus
aurantiacus J-10-fl|Rep: Adenosine deaminase -
Chloroflexus aurantiacus J-10-fl
Length = 346
Score = 94.3 bits (224), Expect = 3e-18
Identities = 59/173 (34%), Positives = 86/173 (49%), Gaps = 9/173 (5%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHG 182
VVGI+L+G+ A F+ RAR +GL++T+H GE V + + ERIGHG
Sbjct: 174 VVGIDLAGDEANFPGTRFVKHFARARAAGLRITVHAGEAAGAWSVRQAIEELGAERIGHG 233
Query: 183 VCIHPKYGGTEETWIA--LCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLC 240
V E+ + + + + +EVC TSNV T+ YESH +L+ GL V L
Sbjct: 234 V------RAVEDPAVLQLIAERGVALEVCPTSNVQTQTVSGYESHPLPQLLRRGLLVTLN 287
Query: 241 TDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGK 293
TDD G+ A L EYR+ + LT ++ L A F + R ++ K
Sbjct: 288 TDDPGISAIDLPHEYRIARDRLGLTTEELRTLQAHALSAAFIDEATRAALLHK 340
>UniRef50_Q7VNV1 Cluster: Adenosine deaminase; n=1; Haemophilus
ducreyi|Rep: Adenosine deaminase - Haemophilus ducreyi
Length = 344
Score = 93.1 bits (221), Expect = 8e-18
Identities = 75/287 (26%), Positives = 128/287 (44%), Gaps = 26/287 (9%)
Query: 30 DTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPR-DTQY-ITK 87
D +L+E + F + SL T EAL A +Q +DG Y E+R P+ TQ +++
Sbjct: 54 DCSDLNEYLRCFDLPLSLLQTPEALSSAVTDLIQRLDQDGLVYAEIRFAPQLHTQRSMSQ 113
Query: 88 KQYIDSIIRAMEASQLQEVEEIADI------AIERHKIHPDT--------------VVGI 127
+ + + +R ++A A++ A + + +T VV I
Sbjct: 114 EDAVKAALRGLQAGLASTSLFKANLILCCMRAADNRSANLETICLAKQYLTKYEAGVVAI 173
Query: 128 ELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHP 187
+L+G + F + A Q G+ T+H GE PE V + L+F RIGHG+
Sbjct: 174 DLAGAEGLFATQHFQQEFDFANQRGVPFTIHAGEAAGPESVQQALDFGATRIGHGI---- 229
Query: 188 KYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVF 247
+ +E L + P+E+C SN+ TK + + + G+ L TD+ V
Sbjct: 230 RAIESETVMKQLIDKRTPLEMCPCSNLQTKTVAQLADYPLRTFLMRGVVATLNTDNMTVS 289
Query: 248 ATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKI 294
T + QEYRL AE + L+ + +L L++ F ++ ++ I
Sbjct: 290 QTCIQQEYRLLAEQYQLSISEAKQLLLNSIAAAFLSNEDKKALLAHI 336
>UniRef50_Q6MHR4 Cluster: Add protein; n=1; Bdellovibrio
bacteriovorus|Rep: Add protein - Bdellovibrio
bacteriovorus
Length = 341
Score = 91.9 bits (218), Expect = 2e-17
Identities = 71/260 (27%), Positives = 129/260 (49%), Gaps = 31/260 (11%)
Query: 22 DEFQIGAGDTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPR- 80
D+F I G ++L F A + ++ E L ++ DG +ELR P
Sbjct: 50 DQFLI-TGPMKDLGSVLNKFMNAQKVLASEEILTRVAYEACEDAFNDGVRLLELRYAPTF 108
Query: 81 ---DTQYITKKQYIDSIIRAMEASQ------------LQEVE--EIADIAIERHKIHPDT 123
+ +T ++ S+++ +E ++ +Q ++ E+A+ ++ H D+
Sbjct: 109 IADGHKSLTFEKIHRSLLKGIEQARKQFPMLIGLICIVQRIKSFEVAEKVVDFAIDHKDS 168
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNP------EEVLEMLNFKPE 177
+ ++L+ N + F P +A+++GL++T+H GE NP + +E+L E
Sbjct: 169 FLALDLADNEEGFDPKVFAPLFQKAKKAGLRITVHSGETPNPVSAKWVHDSIEILG--AE 226
Query: 178 RIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSV 237
RIGHG+ I E + +IP+E+C SN T+ P YE H ++L++AG+ V
Sbjct: 227 RIGHGIQIINDPAVLE----LVKDRRIPLEICPISNYLTQSFPTYEDHPIRKLMQAGVLV 282
Query: 238 VLCTDDKGVFATSLSQEYRL 257
+ +DD GVFAT+LS +Y +
Sbjct: 283 TINSDDPGVFATTLSDDYEV 302
>UniRef50_O86737 Cluster: Probable adenosine deaminase 1; n=3;
Actinomycetales|Rep: Probable adenosine deaminase 1 -
Streptomyces coelicolor
Length = 387
Score = 91.9 bits (218), Expect = 2e-17
Identities = 59/185 (31%), Positives = 94/185 (50%), Gaps = 10/185 (5%)
Query: 103 LQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFG-DFIPALNRARQSGLKVTLHCGE 161
L+ EE A +A + ++ P+ +V L G P +G F P +RA +GL H GE
Sbjct: 190 LESAEETARLATD-DRLRPEGLVSFGLGG-PEIGVARPQFKPYFDRAIAAGLHSVPHAGE 247
Query: 162 VCNPEEVLE-MLNFKPERIGHGVCIHPKYGGTEETWIA-LCQSKIPVEVCLTSNVNTKIT 219
P+ V E +++ + ERIGHG + +A L + +IP+EVC TSN+ T+
Sbjct: 248 TTGPQTVWEALIDLRAERIGHGTS-----SAQDPKLLAHLAERRIPLEVCPTSNIATRAV 302
Query: 220 PDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQC 279
+ H KE + AG+ V + +DD +F T L+ EY + A L +A L+ + +
Sbjct: 303 RTLDEHPIKEFVRAGVPVTINSDDPPMFGTDLNNEYAVAARLLGLDERGLADLAKNGVEA 362
Query: 280 IFSEA 284
F +A
Sbjct: 363 SFLDA 367
>UniRef50_Q5LPC1 Cluster: Adenosine deaminase; n=15;
Rhodobacterales|Rep: Adenosine deaminase - Silicibacter
pomeroyi
Length = 333
Score = 91.5 bits (217), Expect = 2e-17
Identities = 55/174 (31%), Positives = 87/174 (50%), Gaps = 5/174 (2%)
Query: 122 DTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIG 180
D +VG + GN VG GD+ + + AR++GL++T H GE P+ V + + ERIG
Sbjct: 161 DWIVGFGMGGNEGVGKQGDYSWSFDCAREAGLRLTTHAGEFGGPDSVRDAVRVLGVERIG 220
Query: 181 HGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLC 240
HGV E L I +EVC SNV + P + +H L +AG+ V +
Sbjct: 221 HGVRAIEDADLVHE----LADRGITLEVCPGSNVVLGLYPSFAAHPIARLRDAGVRVTIS 276
Query: 241 TDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKI 294
TDD F T++ +EY + A++F A L+ A + F + + R + ++
Sbjct: 277 TDDPPFFHTTMRREYEMLAKAFGWGAEDFADLNATALRAAFCDEDTRSRVAKRL 330
>UniRef50_Q03TM8 Cluster: Adenosine deaminase; n=1; Lactobacillus
brevis ATCC 367|Rep: Adenosine deaminase - Lactobacillus
brevis (strain ATCC 367 / JCM 1170)
Length = 347
Score = 90.2 bits (214), Expect = 6e-17
Identities = 79/269 (29%), Positives = 118/269 (43%), Gaps = 21/269 (7%)
Query: 30 DTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPR--DTQYITK 87
+T +L + Q F + L T E L +A +Q EDG Y+E R P Q +T
Sbjct: 60 ETTSLIDYLQRFQVVTDLMQTPEQLRIAGYDMVQTAAEDGLIYLEARFAPAIFTAQGLTV 119
Query: 88 KQYIDSIIRAMEASQLQ------------EVEEIAD-IAIERHKIH--PDTVVGIELSGN 132
K+ I + + + A + + +AD IA+ + VVG++ +G+
Sbjct: 120 KEAIAATLDGLHAGTREFGIPVNAIVCAMRDQPLADCIAVFKTAADFADQGVVGLDFAGD 179
Query: 133 PAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGT 192
A D PA+ +GL TLH GE + V L RIGHGV + G
Sbjct: 180 EANHPAIDLAPAVKAGLATGLPFTLHAGEAGPVDNVAVSLTLGARRIGHGVHM----SGF 235
Query: 193 EETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLS 252
T ++ +E+C TSNV TK DY + E + AGL V L TDD+ V +L+
Sbjct: 236 PATINQAKRAGATIEMCPTSNVQTKAVADYAAFPLAEFLSAGLKVTLNTDDRTVSDVTLT 295
Query: 253 QEYRLCAESFALTRIQVAKLSLDAAQCIF 281
E + F L + +L+L+A F
Sbjct: 296 SEIMRMHDEFGLNWSLLEQLTLNAIDGAF 324
>UniRef50_Q839J4 Cluster: Adenosine deaminase; n=1; Enterococcus
faecalis|Rep: Adenosine deaminase - Enterococcus
faecalis (Streptococcus faecalis)
Length = 337
Score = 90.2 bits (214), Expect = 6e-17
Identities = 80/296 (27%), Positives = 131/296 (44%), Gaps = 31/296 (10%)
Query: 21 LDEFQIGAGDTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPR 80
L E + +L++ F + T+EAL A + + EDG YIE+R P
Sbjct: 45 LKELVVAPEKCTDLNDYLTRFDFVLTCLQTAEALQAAAYDVISQAAEDGVAYIEVRFAP- 103
Query: 81 DTQYITKKQYIDSIIRA----------------------MEASQLQEVEEIADIAIERHK 118
+Q+ K + I+ A M Q Q +E+I +A H
Sbjct: 104 -SQHTEKGLRLPEIVTAVLTGLKQGEEDFGVKSNALLCGMRHDQQQAIEKIVHLA---HD 159
Query: 119 IHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPER 178
VVG +L+GN F L A Q + +TLH GE + V + + R
Sbjct: 160 FRETGVVGFDLAGNEVDFPPYTFEDVLALANQLSIPLTLHAGECGCGKNVADAVTLGATR 219
Query: 179 IGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVV 238
IGHG+ + T E L + K+ +E+C TSN T + F++ IEAGL+V
Sbjct: 220 IGHGIALKD----TPEYLALLKEKKVLLEMCPTSNFQTGTVKTLAEYPFQQFIEAGLAVC 275
Query: 239 LCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKI 294
+ TD++ V T+L++E+ A + L+ ++ +L+ +A F + ++L+ KI
Sbjct: 276 INTDNRTVSDTTLTKEFMKLATWYQLSYDEMKQLTKNALAGAFLSPDEKKLLNQKI 331
>UniRef50_Q6A5I4 Cluster: Adenosine deaminase; n=1;
Propionibacterium acnes|Rep: Adenosine deaminase -
Propionibacterium acnes
Length = 341
Score = 89.4 bits (212), Expect = 1e-16
Identities = 52/187 (27%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Query: 107 EEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPE 166
E++ D+A+ H VVG++++G F AL R + +G+ +T+H GE PE
Sbjct: 155 EDVVDLAVN----HAPGVVGVDVAGPEDGFPLAPFTNALTRVQAAGIHLTVHAGEAAGPE 210
Query: 167 EVLEMLNFKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYES 224
+L+ LN ER+GHGV I G T + +++P+EVC TSN T I
Sbjct: 211 SILDALNHGAERLGHGVRIIEDRDESGWGPTAQQVLSNQVPLEVCPTSNTQTGICRKVAE 270
Query: 225 HHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEA 284
H L G ++ + D++ + T+ S+E L +++ R +A Q F
Sbjct: 271 HPLSTLWSTGFNITVSCDNRLMSRTTTSREISLVSQALCWNRDDALAAQRNALQAAFCSQ 330
Query: 285 NIRELII 291
+ ++ ++
Sbjct: 331 DDKQSLV 337
>UniRef50_Q8D6Q8 Cluster: Adenosine deaminase; n=13; Bacteria|Rep:
Adenosine deaminase - Vibrio vulnificus
Length = 331
Score = 89.0 bits (211), Expect = 1e-16
Identities = 56/189 (29%), Positives = 95/189 (50%), Gaps = 11/189 (5%)
Query: 81 DTQYITKKQYIDSIIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGD 140
+ QY YI SI+R M Q++ V E A +H D +V +L+G+ G +
Sbjct: 126 EAQYDIHGNYILSILRTMPKDQIKAVLE----AGAKHL--NDGIVAFDLAGSEVPGFCHE 179
Query: 141 FIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFK-PERIGHGVCIHPKYGGTEETWIAL 199
F+P A++ G ++T+H GE + V + ++ ER+GHG+ IH E + +
Sbjct: 180 FVPYAQYAKELGYRITIHAGEQGAGQNVYDAISLLGAERVGHGIFIH----NHPEAYQLV 235
Query: 200 CQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCA 259
++ +E C +SNV TK H K + G++V + TD++ V T+++ E R
Sbjct: 236 KGEEVALETCPSSNVQTKAVNSLSEHPIKAFYKDGIAVTINTDNRTVSNTTMTDEVRKVV 295
Query: 260 ESFALTRIQ 268
E+F LT +
Sbjct: 296 EAFELTEAE 304
>UniRef50_UPI0000499E34 Cluster: adenosine deaminase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: adenosine deaminase -
Entamoeba histolytica HM-1:IMSS
Length = 348
Score = 87.8 bits (208), Expect = 3e-16
Identities = 78/293 (26%), Positives = 134/293 (45%), Gaps = 30/293 (10%)
Query: 21 LDEFQIGAGDTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTP- 79
L++ + D +L + + F I + + T + + ++ DGC Y+E R P
Sbjct: 50 LNKLVMMTNDCESLVQYLKAFDIINLVLQTKDNIERTMFECCEDAYLDGCTYVEFRFAPI 109
Query: 80 -RDTQYITKKQYIDSIIRAMEASQ----------------LQEVEEI--ADIAIERHKIH 120
+ ++ K+ +++ I ++ ++ L E E + A +A+E
Sbjct: 110 QSTNKGLSMKEVMEACIAGVKKAEKKYGIVVRLIVCAMRHLSEEESLKAAQLAVE---FK 166
Query: 121 PDTVVGIELSGNPAVGNF-GDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERI 179
D VVG +L+G P G A A G+ +T+H GE E V + + ERI
Sbjct: 167 NDHVVGFDLAG-PENGFMPSRHKKACQYAFDHGIHITIHAGEAAGYESVDDAIKNHAERI 225
Query: 180 GHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVL 239
GHGV + +ET + ++K+ VE CLTSN+ TK E H +L+E G+ +
Sbjct: 226 GHGV----RLLENKETIKNVIENKVIVECCLTSNIQTKAINKMEDHPILQLMELGIPCTI 281
Query: 240 CTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSE-ANIRELII 291
TD+ V + SLS E L F + Q+ +L +++ + F E +IR +I
Sbjct: 282 NTDNTTVSSCSLSGEDELFTNLFGFSNEQIVELIMNSFRAAFIEDESIRTKLI 334
>UniRef50_Q98GV2 Cluster: Adenosine deaminase; n=9;
Alphaproteobacteria|Rep: Adenosine deaminase - Rhizobium
loti (Mesorhizobium loti)
Length = 324
Score = 87.8 bits (208), Expect = 3e-16
Identities = 52/172 (30%), Positives = 85/172 (49%), Gaps = 5/172 (2%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHG 182
V G ++G+ VG D++ A AR++GL +T+H GE+ E V L+ +P RIGHG
Sbjct: 152 VTGFGVAGDERVGEMEDYVRAFEIAREAGLGITIHAGELTGWETVQAALDHIRPSRIGHG 211
Query: 183 VCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTD 242
V + + + I +E C SN+ K+ + H L AG V L +D
Sbjct: 212 V----RAIENPDLVRRIADEGIVLECCPGSNIALKVFDSFADHPLPALQAAGCKVTLNSD 267
Query: 243 DKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKI 294
D F TSL +EY + AE FA+ +A ++ A + F + + ++ ++
Sbjct: 268 DPPYFWTSLKREYDIAAEHFAMNEKALAAVTRTAIEAAFVDRKTKAALLARL 319
>UniRef50_Q97EV1 Cluster: Adenosine deaminase; n=2; Clostridium|Rep:
Adenosine deaminase - Clostridium acetobutylicum
Length = 334
Score = 86.6 bits (205), Expect = 7e-16
Identities = 66/247 (26%), Positives = 119/247 (48%), Gaps = 21/247 (8%)
Query: 33 NLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTP--RDTQYITKKQY 90
+L E + F + E + T L++ ++DG Y E+R P Q + +
Sbjct: 59 SLKEYLEKFYFPIRVMQKKENIYRVTMELLEDSKKDGIEYTEIRFAPFQHTEQDLNENDV 118
Query: 91 IDSIIRAME--ASQLQEVEEIADIAIERHKIHPDT-VVGIELSGNPAV------GNFGDF 141
+++ + A++ S+L + ++ + +V + S N V GN DF
Sbjct: 119 VEAALEALQDGESKLGIHSNLILCSLRHDPVERSIDLVNLANSYNEGVCAVDLAGNESDF 178
Query: 142 IPALNR-----ARQSGLKVTLHCGEVCNPEEVLEMLNF-KPERIGHGVCIHPKYGGTEET 195
P L++ A +G+K+T+H GE E +L+ + +RIGHG+ + +EE
Sbjct: 179 PPELHKEAFDLAYDNGIKITIHAGETGIAENILKSIKLLHADRIGHGIFAYK----SEEI 234
Query: 196 WIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEY 255
+ ++++P+E+C SNV+TK +Y++H FK+ + G+ V L TD++ V SL EY
Sbjct: 235 LQYVIENQVPLEMCPKSNVDTKAVKNYKNHPFKKYFDLGVKVTLNTDNRTVSNVSLVDEY 294
Query: 256 RLCAESF 262
A F
Sbjct: 295 LNLANIF 301
>UniRef50_Q9KNI7 Cluster: Adenosine deaminase; n=81;
Gammaproteobacteria|Rep: Adenosine deaminase - Vibrio
cholerae
Length = 334
Score = 85.0 bits (201), Expect = 2e-15
Identities = 53/173 (30%), Positives = 86/173 (49%), Gaps = 9/173 (5%)
Query: 124 VVGIELSGNPAVGNFGD-FIPALNRARQSGLKVTLHCGEVCNPEEVLEML-NFKPERIGH 181
+V ++L+G+ +G GD FI + R +GL VT+H GE PE + + + + RIGH
Sbjct: 163 IVAVDLAGDE-LGQPGDRFIQHFKQVRDAGLHVTVHAGEAAGPESMWQAIRDLGATRIGH 221
Query: 182 GV-CIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLC 240
GV IH + L Q +I +E CLTSN+ T +H K +E G+ +
Sbjct: 222 GVKAIHDP-----KLMDYLAQHRIGIESCLTSNLQTSTVDSLATHPLKRFLEHGILACIN 276
Query: 241 TDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGK 293
TDD V L EY + A L++ Q+ + L+ + F + ++ ++ K
Sbjct: 277 TDDPAVEGIELPYEYEVAAPQAGLSQEQIRQAQLNGLELAFLSDSEKKALLAK 329
>UniRef50_Q1IVQ0 Cluster: Adenosine deaminase; n=1; Acidobacteria
bacterium Ellin345|Rep: Adenosine deaminase -
Acidobacteria bacterium (strain Ellin345)
Length = 354
Score = 83.0 bits (196), Expect = 9e-15
Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 5/159 (3%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHG 182
VVGI + G+ A G +F A ++GL +T H GE PE + +N K ERIGHG
Sbjct: 187 VVGIGIGGDEAGGPAENFREIYENAAKNGLHLTAHAGESTGPESIWSAMNDLKAERIGHG 246
Query: 183 VCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTD 242
+H E L +S +EVC++SNV T H ++L +AG+ + + TD
Sbjct: 247 --LHAIED--PELVEHLAKSGTAIEVCVSSNVRTGCCRALAEHPVRKLFDAGVKITIATD 302
Query: 243 DKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
D +F +L+ EY++ + F + + +++ ++ + F
Sbjct: 303 DPEMFGCTLTGEYQILQDQFGFSDDDLRRVARNSFEASF 341
>UniRef50_Q5FIX0 Cluster: Adenosine deaminase; n=6;
Lactobacillus|Rep: Adenosine deaminase - Lactobacillus
acidophilus
Length = 333
Score = 82.6 bits (195), Expect = 1e-14
Identities = 51/159 (32%), Positives = 81/159 (50%), Gaps = 4/159 (2%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGV 183
VVG++L+G + N+A+Q G+ T+H GE P+ + + L +RIGHG+
Sbjct: 165 VVGLDLAGAEGPIPNIKYKSFFNQAQQLGVPYTIHAGEADGPDSIRQALAMGAKRIGHGI 224
Query: 184 CIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDD 243
T+E L +I +E C TSN+NTK +S+ K+L+ G+ V L +DD
Sbjct: 225 RCTEDTQLTQE----LIDQQIVLECCATSNMNTKAFDQIDSYPIKKLLHKGMKVTLNSDD 280
Query: 244 KGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFS 282
V T+L EY++ + LT + L L+A F+
Sbjct: 281 MTVSDTNLLHEYKVLEKRTDLTPEEETTLYLNAVDAAFT 319
>UniRef50_A6BDK9 Cluster: Putative uncharacterized protein; n=2;
Clostridiales|Rep: Putative uncharacterized protein -
Dorea longicatena DSM 13814
Length = 322
Score = 81.4 bits (192), Expect = 3e-14
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 21/279 (7%)
Query: 30 DTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTP--RDTQYITK 87
D R+L+E + F + L A L+ +++ CY E+R P +T +
Sbjct: 45 DCRSLNEYLEKFDLPGKCIMDETGLKEAGYDVLKSMKQENVCYAEIRFAPLLSETPDMNC 104
Query: 88 KQYIDSIIRAMEASQLQEVEEIADI--AIERHKIHPDT-------------VVGIELSGN 132
+ I++++ +E + E I A+ H + V +L+G
Sbjct: 105 NKVIEALLAGLEKGKRDFGIEYGVITCAMRHHSEEENARMLRTAREYLGHGVCAADLAGA 164
Query: 133 PAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGT 192
++ +F+ + + G+ TLH GE + + +L+ + RIGHG+ + G
Sbjct: 165 ESLYPMSEFMELFKKTKALGMPFTLHAGECGSVQNILDSVETGAGRIGHGIAMR----GY 220
Query: 193 EETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLS 252
+ L + I +E+C SN+ TK +++ +E + AGL V + TD++ V T+L+
Sbjct: 221 ADVQKELQKKGIGIEMCPISNLQTKAVESTKNYPMREFLNAGLKVTVNTDNRTVSNTTLT 280
Query: 253 QEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELII 291
+E +++ +T ++ + +A F++ ++E ++
Sbjct: 281 KELEFIQKNYRITDEEIHLMMRNAVDVAFADDAVKERML 319
>UniRef50_Q8XHH8 Cluster: Adenosine deaminase; n=8; Bacteria|Rep:
Adenosine deaminase - Clostridium perfringens
Length = 332
Score = 81.4 bits (192), Expect = 3e-14
Identities = 66/279 (23%), Positives = 131/279 (46%), Gaps = 26/279 (9%)
Query: 30 DTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTP--RDTQYITK 87
+ +L + F++ L +E L +++ ++ YIE+R P + +T+
Sbjct: 52 ECNSLEDYLNRFALPVKLLQRAENLERVAFELMEDASKENVKYIEIRFAPLLHLEKGMTQ 111
Query: 88 KQYIDSIIRAM-EASQLQEV--------------EEIADIAIERHKIHPDTVVGIELSGN 132
K+ I+S+I+ + +A +L ++ + + ++ E VV I+L+G
Sbjct: 112 KEVIESVIKGIRKAEELYDIKGNLILSCLRHHSIDSVYEVIEEGKNFIGKGVVAIDLAGG 171
Query: 133 PAVGNFGDFIPALNRARQSGLKVTLHCGEVC---NPEEVLEMLNFKPERIGHGVCIHPKY 189
G + + AR+SG +VT+H GE N + +E+L ERIGHG+ I
Sbjct: 172 ELEGFVKPYEEVMKLARESGFRVTIHAGETGYGKNVRDAIELLG--AERIGHGLFIF--- 226
Query: 190 GGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFAT 249
EE + + + + +E+C SN++TK YE H + + + V L TD++ V
Sbjct: 227 -NDEEAYNLVKEKGVTLEMCPKSNIDTKGVNKYEDHPIYKYHKDNIRVNLSTDNRTVSNI 285
Query: 250 SLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRE 288
+L++E+ ++F + K+ L++ + F ++E
Sbjct: 286 NLTEEFENVHKTFNIDFEDYKKIYLNSVEASFCSEELKE 324
>UniRef50_Q9CIR9 Cluster: Adenosine deaminase; n=3; Lactococcus
lactis|Rep: Adenosine deaminase - Lactococcus lactis
subsp. lactis (Streptococcus lactis)
Length = 352
Score = 81.0 bits (191), Expect = 3e-14
Identities = 62/244 (25%), Positives = 117/244 (47%), Gaps = 21/244 (8%)
Query: 30 DTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRD--TQYITK 87
+T+NL E Q F L T + L +A +++ D YIE+R P + +T
Sbjct: 63 NTKNLLEYLQRFDFVLPLLQTYKNLELAAYDVVRQAANDNIKYIEIRFAPSQHLLENLTL 122
Query: 88 KQYIDSIIRAMEASQ---------------LQEVEEIADIAIERHKIHPDTVVGIELSGN 132
++ ++++I + ++ + ++++ + KI + +VG +++G+
Sbjct: 123 EEAVEAVIAGLSRAENDFDIRANALVCGLKQEPIQKLQKLLPLFDKIPDEHLVGFDMAGD 182
Query: 133 PAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEE-VLEMLNFKPERIGHGVCIHPKYGG 191
F+ ++ + G+ VTLH GE E+ +L+ + RIGHG+
Sbjct: 183 ELNYPQEKFVDLIHDIKIKGVNVTLHAGECPACEKNILDSIAMGASRIGHGIMTKNLSEA 242
Query: 192 TEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSL 251
++ I + +I +E+ TSN TK + + FKEL + G+ V L TD++ V AT+L
Sbjct: 243 EQKMMI---EKQIVLEMAPTSNFQTKAVTELAQYPFKELYDKGIHVTLNTDNRMVSATNL 299
Query: 252 SQEY 255
S+EY
Sbjct: 300 SKEY 303
>UniRef50_A6FY15 Cluster: Adenosine deaminase; n=1; Plesiocystis
pacifica SIR-1|Rep: Adenosine deaminase - Plesiocystis
pacifica SIR-1
Length = 358
Score = 80.6 bits (190), Expect = 5e-14
Identities = 48/152 (31%), Positives = 76/152 (50%), Gaps = 5/152 (3%)
Query: 143 PALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHGVCIHPKYGGTEETWIALCQ 201
P A+ +GL+ H GE P V L + +RIGHGV E L +
Sbjct: 207 PVFAEAKAAGLRSVPHAGEQDGPASVRANLERLQADRIGHGVRAIEDPALVAE----LRE 262
Query: 202 SKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAES 261
IP+EVC TSNV + P H +L++AGL+V L +DD +F T+L EYR CA +
Sbjct: 263 RAIPLEVCPTSNVALGVYPSLADHPLPQLLDAGLAVTLASDDPPLFGTTLVDEYRRCAAT 322
Query: 262 FALTRIQVAKLSLDAAQCIFSEANIRELIIGK 293
+ + Q+ ++ + F +A+ + ++ +
Sbjct: 323 YGWDKAQLLAIAQAGVEHSFLDADRKRALLAE 354
>UniRef50_Q1N1B2 Cluster: Adenosine deaminase; n=5;
Proteobacteria|Rep: Adenosine deaminase - Oceanobacter
sp. RED65
Length = 350
Score = 78.6 bits (185), Expect = 2e-13
Identities = 56/187 (29%), Positives = 88/187 (47%), Gaps = 8/187 (4%)
Query: 107 EEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPE 166
EE A +E+ K + D ++G+ L + F AR GL+ H GE P
Sbjct: 159 EEAAFDTLEQAKPYLDHIIGVGLDSSELGHPPEKFERVFKAARDLGLRAVAHAGEE-GPT 217
Query: 167 EVLE--MLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYES 224
+E + K ERI HGV + +E+ + +IP+ VC SN+ K+ E
Sbjct: 218 SYIENALERLKIERIDHGV----QCTQSEQLMQEIADKQIPLTVCPQSNIRLKVYEKMEQ 273
Query: 225 HHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF-SE 283
H EL+E GL V++ +DD F + Q Y A++ +TR Q A+L+ ++ F E
Sbjct: 274 HPILELLEKGLKVMVNSDDPAFFGGYVLQNYLSLAQALNMTREQAAQLAYNSISSSFCGE 333
Query: 284 ANIRELI 290
+R +I
Sbjct: 334 ERMRTMI 340
>UniRef50_A5UX82 Cluster: Adenosine deaminase; n=5; Chloroflexi
(class)|Rep: Adenosine deaminase - Roseiflexus sp. RS-1
Length = 353
Score = 77.8 bits (183), Expect = 3e-13
Identities = 50/162 (30%), Positives = 75/162 (46%), Gaps = 5/162 (3%)
Query: 121 PDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERI 179
P VVG + G+ F AR++GL+V H GEV P V ++ R+
Sbjct: 170 PYGVVGWSIGGDEINHPPEPFAGVFAAARRAGLQVMAHAGEVVGPASVWGAIDALGVRRV 229
Query: 180 GHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVL 239
GHG+ + E AL I ++VC TSNV T ++H + L +AG+ + +
Sbjct: 230 GHGI----RSIDDPELITALRMRNIVLDVCPTSNVRTGAVSGLDAHPLRRLFDAGVPLTI 285
Query: 240 CTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
TDD F T+L EYR+ F T + +++L A F
Sbjct: 286 NTDDPVFFNTTLCNEYRMATRLFGFTADDLTRIALTGAHAAF 327
>UniRef50_Q8DTN8 Cluster: Adenosine deaminase; n=16;
Lactobacillales|Rep: Adenosine deaminase - Streptococcus
mutans
Length = 349
Score = 77.8 bits (183), Expect = 3e-13
Identities = 66/280 (23%), Positives = 125/280 (44%), Gaps = 24/280 (8%)
Query: 30 DTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDT--QYITK 87
D+ L + + F L T +AL +A ++ + YIE+R P + + ++
Sbjct: 64 DSETLLDYLKTFDFIRPLLQTQKALSLAAYDVAKQAAAEHVLYIEIRFAPELSMDKGLSA 123
Query: 88 KQYIDSIIRAMEASQLQEVEEIADIAI----ERHKIHPDTVV-------GIELSGNPAVG 136
Q ++++ + ++ +Q ++ +A + I + K + +E +G G
Sbjct: 124 VQVVEAVEKGLQKAQ-RDFNIVAKVLICGMRQSSKQLTKEIFRQINQAKSLEFAGFDFAG 182
Query: 137 NFGDFIPA-----LNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGG 191
N DF P + ++ +T H GE P + + + +R+GH IH
Sbjct: 183 NEHDFPPQEIADLIRFTQRLDRPMTFHAGECGCPSHIAQSIALGIKRLGHVTAIHDH--- 239
Query: 192 TEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSL 251
E ++K+ E+CLTSN+ TK ++EL EAG + + TD++ V T+L
Sbjct: 240 -PELIADFVENKVTAELCLTSNLQTKAAKSLAEFPYQELYEAGAKITINTDNRTVSNTNL 298
Query: 252 SQEYRLCAESFALTRIQVAKLSLDAAQCIF-SEANIRELI 290
++EY+L + F + + +A + F SEA EL+
Sbjct: 299 TKEYQLFVDYFGTSLADFYHFNQNAIEASFASEAEKAELL 338
>UniRef50_Q5BFL8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 307
Score = 75.8 bits (178), Expect = 1e-12
Identities = 67/233 (28%), Positives = 112/233 (48%), Gaps = 39/233 (16%)
Query: 38 FQVFSIA-HSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQY--ITKKQYIDSI 94
F VF+ + + L + E++ AT LQ F +DG Y+ELR+ PR + T+ QY+ ++
Sbjct: 80 FGVFNQSIYQLVNDLESVAYATTSVLQAFLDDGVRYLELRTIPRASPNAAFTRDQYLSTV 139
Query: 95 -------------------IRAMEASQL----QEVEEIADIAIERHKIHPDTVVGIELSG 131
I M+ QL EI D+AI + V+G+++ G
Sbjct: 140 LDTIAEFKSQNSGKISVYLILGMDRGQLVADSTHAHEIVDLAIANRE---RGVIGVDVCG 196
Query: 132 NPAVGNFGDFIPALNRARQSGLKVTLHCGEVCN---PEEVLEMLNFKPERIGHGVCIHPK 188
NP G+ A +A++ GL +T+H EV + EE+ ML+F P+R+GH IH
Sbjct: 197 NPTKGDISLCRDAFAKAKKHGLSLTVHFAEVHSMGLHEELQTMLSFNPDRLGH--VIHVP 254
Query: 189 YGGTEETWIALCQSKIPVEVCLTSNVNTKI-TPDYESHHFKELIEAGLSVVLC 240
+E + + ++ +E+C++ NV+ K+ + HHF V+LC
Sbjct: 255 DDIKQE----IARKRLGLELCISCNVHAKMFDGGFLDHHFGYWRHEECPVILC 303
>UniRef50_Q5QWC8 Cluster: Adenosine deaminase; n=2; Idiomarina|Rep:
Adenosine deaminase - Idiomarina loihiensis
Length = 410
Score = 75.4 bits (177), Expect = 2e-12
Identities = 48/157 (30%), Positives = 85/157 (54%), Gaps = 17/157 (10%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHG 182
+VG++++G G+F A ++ L T+H GE E + E L +R+GHG
Sbjct: 208 IVGLDIAGQEIGYPAGEFKEVYEYAHENFLLKTVHAGEAYGAESIFEALTKCHADRLGHG 267
Query: 183 VCIH------------PK-YGGTEETWIALCQSKIPVEVCLTSNVNTKIT-PDYESHHFK 228
+ PK YG + ++IA +I VEVCLTSN+ T D ++H+F+
Sbjct: 268 YSLFSPEMTQDPSIEDPKAYGESLASYIA--DRRIAVEVCLTSNLQTNPDIGDIKNHNFQ 325
Query: 229 ELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALT 265
+++ L+ ++CTD++ V T++S EY+L ++F ++
Sbjct: 326 HMLDNRLATIICTDNRLVSRTTVSNEYQLAVDNFDIS 362
>UniRef50_Q8KNI1 Cluster: CalS5; n=1; Micromonospora
echinospora|Rep: CalS5 - Micromonospora echinospora
(Micromonospora purpurea)
Length = 354
Score = 75.4 bits (177), Expect = 2e-12
Identities = 47/150 (31%), Positives = 70/150 (46%), Gaps = 4/150 (2%)
Query: 141 FIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALC 200
F A+ A G+ H GE PE V + L F+P RIGHG+ + AL
Sbjct: 189 FGEAVRWAAARGVPFVPHAGEAVGPEGVWDCLPFRPPRIGHGI----RSVEDPRLVAALR 244
Query: 201 QSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAE 260
+ +EVC TSN+ T + + +H + L +AG+ + L TDD +F T L E+R E
Sbjct: 245 DRAVVLEVCPTSNLRTGVVSEPGAHPLRRLWDAGVRLTLNTDDPSMFHTDLLAEHRFAVE 304
Query: 261 SFALTRIQVAKLSLDAAQCIFSEANIRELI 290
T ++A ++L A RE +
Sbjct: 305 WHGFTVAELAAMTLIGVDAALLPATEREAL 334
>UniRef50_Q8EZR9 Cluster: Adenosine deaminase; n=4; Leptospira|Rep:
Adenosine deaminase - Leptospira interrogans
Length = 442
Score = 74.9 bits (176), Expect = 2e-12
Identities = 48/138 (34%), Positives = 72/138 (52%), Gaps = 7/138 (5%)
Query: 120 HPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPER 178
HP+ V+GI L G +G D+ +AR++GL+V H GE P + E + K ER
Sbjct: 258 HPE-VIGIGLGGAELMGPARDYQGVFQKAREAGLRVVAHSGEDDGPWAIWEAVELLKAER 316
Query: 179 IGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNT-KITPDYESHHFKELIEAGLSV 237
IGHG E L ++ IP+E+C+TSNV T K ++H + + GL +
Sbjct: 317 IGHGTSAIQ----DPELVKYLRENHIPIEICVTSNVFTGKYVRKEQNHPVRYYYDQGLPL 372
Query: 238 VLCTDDKGVFATSLSQEY 255
+ TDD +F +L+ EY
Sbjct: 373 SINTDDPEIFNVNLTYEY 390
>UniRef50_Q3WB85 Cluster: Adenosine deaminase; n=5;
Actinomycetales|Rep: Adenosine deaminase - Frankia sp.
EAN1pec
Length = 406
Score = 74.9 bits (176), Expect = 2e-12
Identities = 57/169 (33%), Positives = 78/169 (46%), Gaps = 7/169 (4%)
Query: 122 DTVVGIELSGNPAVG-NFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNF-KPERI 179
D V+ + L G P +G F P AR +GL H GE P + + L + ERI
Sbjct: 220 DGVIALGLGG-PEIGVPRPQFGPVFTAARDAGLHCVPHAGETTGPRTIWDSLEYLHAERI 278
Query: 180 GHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVL 239
GHG E L + +IP+EV TSN+ T Y H E+I GL V L
Sbjct: 279 GHGTSALGDPALVEH----LRRHRIPLEVSPTSNLCTGAVASYGVHPLPEMIAQGLQVNL 334
Query: 240 CTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRE 288
+DD +F T+L EY S L+R QV ++ A + F A+ +E
Sbjct: 335 NSDDPPMFNTTLRAEYLHALRSLRLSRQQVFDVAAAAVEHSFLPADGKE 383
>UniRef50_A0Q5S2 Cluster: Deoxyadenosine deaminase/adenosine
deaminase; n=7; Francisella tularensis|Rep:
Deoxyadenosine deaminase/adenosine deaminase -
Francisella tularensis subsp. novicida (strain U112)
Length = 346
Score = 74.5 bits (175), Expect = 3e-12
Identities = 69/300 (23%), Positives = 131/300 (43%), Gaps = 19/300 (6%)
Query: 17 TNTFLDEFQIGAGDTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELR 76
T+ L E+ G +++ CF F+IA ++ T E L +++ D Y+E R
Sbjct: 41 TSAELLEWFYGEFSSKDFDRCFAAFNIAGAVMQTKEGLERVAFEFVEDHALDNVIYVEAR 100
Query: 77 STP--RDTQYITKKQYIDSIIRAM-EASQLQEVEE----------IADIAIERHKIHP-- 121
P Q ++ + I+SI A + ++E DI +E ++
Sbjct: 101 FCPYFHRNQDLSYAEIIESISAGFARAKRKYDIEAGILVCGMYSLSDDINLELAELCTKY 160
Query: 122 DTVVGIELSGNPAVGNFGDFIP-ALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIG 180
+VG +++G G+ +P L R + +K T+H GE + + + RIG
Sbjct: 161 SQIVGYDVAGMDIAGDVSKVLPKTLEFLRYNNVKFTVHSGEFSSISNIKASILSGASRIG 220
Query: 181 HGVCIHPK--YGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVV 238
HG ++ E L I +E ++SNV I +E+H ++ ++ +S+
Sbjct: 221 HGCNLYKTKDLDLLREVIALLIDRNIHIESNVSSNVALGIVDSFENHSYQRMLADNISIA 280
Query: 239 LCTDDKGVFAT-SLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKILKF 297
L TDD+ + +++ EY L+ + ++L+AA+ F + ++ II K+ F
Sbjct: 281 LNTDDRLMLRNITMTDEYYNAYLKNNLSFANMVIMNLNAARAAFINDDSKQKIIAKLKSF 340
>UniRef50_A1K1Z8 Cluster: Adenosine deaminase; n=2; Bacteria|Rep:
Adenosine deaminase - Azoarcus sp. (strain BH72)
Length = 340
Score = 74.1 bits (174), Expect = 4e-12
Identities = 49/176 (27%), Positives = 82/176 (46%), Gaps = 5/176 (2%)
Query: 107 EEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPE 166
EE +E+ H + G+ L + F R R+ GL + H GE P
Sbjct: 151 EEDGFATLEQALPHLARIHGVGLDSSEKGHPPAKFARLFARCRELGLHIVAHAGEEGPPA 210
Query: 167 EVLEMLNF-KPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESH 225
+ E L+ + ERI HGV E L + ++P+ VC SNV + + H
Sbjct: 211 YIEEALDILQVERIDHGVRAAESAALMER----LAREQVPLTVCPLSNVKLCVFERLQDH 266
Query: 226 HFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
+ K+L++AGL V + +DD F + Q Y+ AE+ L+R ++ +L+ ++ + F
Sbjct: 267 NLKQLLDAGLKVTINSDDPAYFGGYVGQNYQQTAEALGLSRTELKQLAKNSLEASF 322
>UniRef50_A2EQP3 Cluster: Adenosine deaminase family protein; n=2;
Trichomonas vaginalis G3|Rep: Adenosine deaminase family
protein - Trichomonas vaginalis G3
Length = 732
Score = 74.1 bits (174), Expect = 4e-12
Identities = 50/166 (30%), Positives = 77/166 (46%), Gaps = 7/166 (4%)
Query: 107 EEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPE 166
+E++DIA + VVG +L+G+ I A R + VT+H GE P+
Sbjct: 154 KEVSDIAWRFRNLG---VVGFDLAGSENGFPPHWHIDAFRTMRHKAIPVTIHAGEAYGPK 210
Query: 167 EVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHH 226
+ L+ RIGHG I +E + ++ +E C++SNV TK E H
Sbjct: 211 SIQYALDCNATRIGHGTRIVESEPLLQE----VIDRRVTLECCVSSNVQTKAIAKLEDHP 266
Query: 227 FKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKL 272
K+L E G+ V CTD+ V +LS EY L F ++ ++
Sbjct: 267 IKKLFERGVITVPCTDNCTVSGVTLSGEYFLLQNKFGFNVEELVRM 312
>UniRef50_A5IGY4 Cluster: Adenosine deaminase; n=4; Legionella
pneumophila|Rep: Adenosine deaminase - Legionella
pneumophila (strain Corby)
Length = 326
Score = 72.9 bits (171), Expect = 9e-12
Identities = 49/172 (28%), Positives = 85/172 (49%), Gaps = 5/172 (2%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKP-ERIGHG 182
V G L G+ A F A SGL+ T+H GE + + + E + P +RIGHG
Sbjct: 157 VTGFGLGGDEAKFPPQLFAKTYQIAADSGLECTVHAGEFDSAKGMEEAMKTLPIKRIGHG 216
Query: 183 VCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTD 242
V + + + + I +EVC TSN+ + D SH F +L EAG+ V + +D
Sbjct: 217 VRVID----SPDIMAMVKDQGIALEVCPTSNIFLGLFKDMNSHPFPKLYEAGIKVSINSD 272
Query: 243 DKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKI 294
D +T+L+QEY+ +++ + + ++ A + F + R+ ++ K+
Sbjct: 273 DPPFMSTTLAQEYKRVQKAYGYSNDTMNNITRMAIEAAFVDEKTRKELLTKL 324
>UniRef50_Q49UM8 Cluster: Putative adenosine deaminase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative adenosine deaminase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 324
Score = 72.5 bits (170), Expect = 1e-11
Identities = 51/192 (26%), Positives = 95/192 (49%), Gaps = 9/192 (4%)
Query: 91 IDSIIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIP-ALNRAR 149
++ ++ AM ++ + + D H+ H + + GI+ +G P VG + I +
Sbjct: 128 VNLLVCAMRQHHTEQNQTLFDFI---HQHHHEAICGIDFAG-PEVGFPTEAIEDTIKYGL 183
Query: 150 QSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVC 209
G +TLH GE V+E + +RIGHGV I+ +++ + ++ + +E+C
Sbjct: 184 DKGFNLTLHAGECGCMHNVIEGIKLGSKRIGHGVAINQD----KQSLQFVKENDVLLEMC 239
Query: 210 LTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQV 269
SN+ TK E+ + L+E + ++ TD++ V TSL++EY L E+ +T QV
Sbjct: 240 PKSNIQTKAITGLEALNLPYLLEQDIPFLINTDNRTVTQTSLNEEYTLLIENEMMTLEQV 299
Query: 270 AKLSLDAAQCIF 281
++ A F
Sbjct: 300 KYINERAVDYAF 311
>UniRef50_Q2S4S0 Cluster: Adenosine deaminase; n=1; Salinibacter
ruber DSM 13855|Rep: Adenosine deaminase - Salinibacter
ruber (strain DSM 13855)
Length = 396
Score = 71.7 bits (168), Expect = 2e-11
Identities = 43/147 (29%), Positives = 76/147 (51%), Gaps = 8/147 (5%)
Query: 109 IADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEV 168
+A++A+E + VV +L+G A + A RAR + L +T+H GE P+ +
Sbjct: 202 LAELAVEYQH---EGVVAFDLAGGEAGNPPKGHLHAFYRARNNLLNLTIHAGEAWGPDSI 258
Query: 169 LEMLNF-KPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHF 227
+ L + RIGHG+ + E +IP+E+C TSNV+T+ P E+H
Sbjct: 259 RQALFYCGAHRIGHGISLRKD----PELMQYFADHRIPLEICPTSNVDTQAVPSLEAHPI 314
Query: 228 KELIEAGLSVVLCTDDKGVFATSLSQE 254
+ + + + V + TD++ TS+++E
Sbjct: 315 ETYVRSNIPVTVNTDNRLFSRTSVTKE 341
>UniRef50_A7H6H4 Cluster: Adenosine deaminase; n=5;
Myxococcales|Rep: Adenosine deaminase - Anaeromyxobacter
sp. Fw109-5
Length = 374
Score = 71.3 bits (167), Expect = 3e-11
Identities = 70/269 (26%), Positives = 120/269 (44%), Gaps = 26/269 (9%)
Query: 33 NLSECFQVFSIAHSLTSTSEALV-MATELTLQEFQEDGCCYIELRSTP--RDTQYITKKQ 89
+L E F + S+ T +AL +A EL L + + Y+E+R +P + +
Sbjct: 69 SLEEYLTAFDVTLSVLQTEDALRRVAYELAL-DCAAENVRYLEVRYSPVLHTRKGLKPTA 127
Query: 90 YIDSIIRAMEASQLQE-VEEIADIAIERHKIHPDT---------------VVGIELSGNP 133
+D+++ + A+ + + I RH I P T VVG +L+G
Sbjct: 128 IVDAVLDGLRAAGRESGIRSNVIICGIRH-IDPQTSVRLAELAVAYKGKGVVGFDLAGAE 186
Query: 134 AVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNF-KPERIGHGVCIHPKYGGT 192
A+ + + VT+H GE PE + + ++ RIGHGV + + G
Sbjct: 187 EGHPASRHREAVQLILDNNVNVTIHAGEAFGPESIAQAVHTCGAHRIGHGVRL--RENGD 244
Query: 193 EETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLS 252
+ L +IP+E+C +SNV T+ YESH K + GL V + TD++ + T+++
Sbjct: 245 LLNY--LNDHRIPLEMCPSSNVQTRSVTGYESHPLKFYFDFGLRVTVNTDNRLITDTTIT 302
Query: 253 QEYRLCAESFALTRIQVAKLSLDAAQCIF 281
+E RL E T + L + + F
Sbjct: 303 KELRLAHERMGFTLEDLCTLLVQGFKSAF 331
>UniRef50_A4FFR1 Cluster: Adenosine deaminase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Adenosine
deaminase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 339
Score = 71.3 bits (167), Expect = 3e-11
Identities = 47/163 (28%), Positives = 78/163 (47%), Gaps = 6/163 (3%)
Query: 122 DTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNF-KPERIG 180
D V GI ++G + F L+ AR +G+ + H GE C + + E ++ +RIG
Sbjct: 149 DEVAGIGMAGEESYP-LEPFADVLDAARDAGVALVHHAGEACGADSIREAIHTGHAQRIG 207
Query: 181 HGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLC 240
HG+ + T E + I +EVC +SNV ++H + AGL+V +
Sbjct: 208 HGIRVLDDPALTAE----IRDRGIALEVCPSSNVLLGFAASPDAHPLAHMRAAGLAVTVN 263
Query: 241 TDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSE 283
TD + T+L+ EY L ++F +A L+ A Q F++
Sbjct: 264 TDIPAIAGTTLTDEYALVRDTFGYDDHDLAALARTAVQACFAD 306
>UniRef50_A0FN94 Cluster: Adenosine deaminase; n=1; Burkholderia
phymatum STM815|Rep: Adenosine deaminase - Burkholderia
phymatum STM815
Length = 337
Score = 70.9 bits (166), Expect = 4e-11
Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 8/182 (4%)
Query: 102 QLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGE 161
Q E A AI + + H ++ + L G F+ A RAR+ G + T H GE
Sbjct: 142 QRHRTEASALAAIAQAEPHSSRIIALGLGGPERDNPPSRFVRAFERARELGWRTTAHAGE 201
Query: 162 VCNPEEVLEMLNF-KPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITP 220
+ V + + + +RI HGV IAL +IP+ VC SNV K+
Sbjct: 202 EGPADYVSQAIELLRVDRIDHGVAAQQN----ARLVIALAARRIPLTVCPVSNVKLKVFD 257
Query: 221 DYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKL---SLDAA 277
E H+ + L+E+G + + TDD F +L+ + + L+ Q+ ++ D A
Sbjct: 258 KLEHHNARYLLESGCVITINTDDPSYFLANLTDNLYQTSRALDLSDDQIFQIIWNGFDGA 317
Query: 278 QC 279
C
Sbjct: 318 FC 319
>UniRef50_A7AW03 Cluster: Adenosine deaminase, putative; n=1;
Babesia bovis|Rep: Adenosine deaminase, putative -
Babesia bovis
Length = 362
Score = 69.3 bits (162), Expect = 1e-10
Identities = 45/141 (31%), Positives = 70/141 (49%), Gaps = 10/141 (7%)
Query: 120 HPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEV---CNPEEVLEMLNFKP 176
H D +G + +G PA +F F R +G+ +TLH GE CN E + L+F
Sbjct: 186 HRDKFIGFDNAGYPA--DFAPFADQFKRLVDAGVNLTLHAGETPPDCN-ERLAMALDFGA 242
Query: 177 ERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLS 236
+RIGHG+ + + E L + +EVC SN T + + H +++ +AG+
Sbjct: 243 KRIGHGI----ECAKSPEMMKRLIDEDVILEVCPKSNWITNPSINMSDHPIRKIYDAGVK 298
Query: 237 VVLCTDDKGVFATSLSQEYRL 257
V + TDD + SL +EY L
Sbjct: 299 VCINTDDPMMMTNSLHEEYDL 319
>UniRef50_A7RSR8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 366
Score = 68.5 bits (160), Expect = 2e-10
Identities = 50/163 (30%), Positives = 81/163 (49%), Gaps = 9/163 (5%)
Query: 124 VVGIELSGNPAVGNFG---DFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERI 179
VVGI+L+G+ ++G + + A AR+ G+ T+H GE V E L+ ERI
Sbjct: 166 VVGIDLAGDESLGETPATKNHVMAFEEARRVGIHRTVHAGEAGPAASVREALDQLHAERI 225
Query: 180 GHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNT-KITPDYESHHFKELIEAGLSVV 238
GHG H EE + + + +I +E C TS++ T + P ++ H + G +
Sbjct: 226 GHGY--HTLED--EELYDRVLKERIHLETCPTSSILTGAVPPPFKCHPILKFARDGANFS 281
Query: 239 LCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
L +DD V T++ EYR+ + L K +L+AA+ F
Sbjct: 282 LNSDDPLVCDTTIENEYRVAHDEIGLGEEDFKKATLNAAKASF 324
>UniRef50_Q15TP8 Cluster: Adenosine deaminase; n=2;
Gammaproteobacteria|Rep: Adenosine deaminase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 537
Score = 67.3 bits (157), Expect = 5e-10
Identities = 48/177 (27%), Positives = 85/177 (48%), Gaps = 9/177 (5%)
Query: 120 HPDTVVGIELSGNPA--VGNFGDFIPALNRARQS--GLKVTLHCGEVCNPE-EVLEMLNF 174
H D VGI + G G F+ L + RQ + + +H GEV P V + L
Sbjct: 320 HRDIYVGINMVGREDNDKGYPLRFLSTLRKLRQRIPNIPLAIHAGEVDEPNFHVRDTLLL 379
Query: 175 KPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAG 234
RIGHGV + G T + + + VE+ L SN+ + +Y H F E + G
Sbjct: 380 GANRIGHGVNLIDDPG----TMLLMRNDRYLVEINLISNLLLEYVDEYHQHPFPEYLRTG 435
Query: 235 LSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELII 291
+ V L TDD+G++ ++++ EY + + F L+ ++ L+ ++ + F + + ++
Sbjct: 436 IPVSLSTDDRGMWDSNMTDEYFVAVKEFNLSWQELTGLAENSLKHGFVDEQTKRALL 492
>UniRef50_P63908 Cluster: Adenosine deaminase; n=38; Actinobacteria
(class)|Rep: Adenosine deaminase - Mycobacterium bovis
Length = 365
Score = 66.9 bits (156), Expect = 6e-10
Identities = 56/197 (28%), Positives = 91/197 (46%), Gaps = 11/197 (5%)
Query: 108 EIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEE 167
EIA++AI + VVG +++G A + A R + T+H GE
Sbjct: 161 EIAELAI---RFRDKGVVGFDIAGAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPS 217
Query: 168 VLEMLNF-KPERIGHGVCIHPKY-----GGTEETWIA--LCQSKIPVEVCLTSNVNTKIT 219
+ E + F +R+GHGV I GG + +A L +IP+E+C +SNV T
Sbjct: 218 IHEAIAFCGADRLGHGVRIVDDIDVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAV 277
Query: 220 PDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQC 279
H F L A V + TD++ + TS+S E E+F +A+ +++A +
Sbjct: 278 ASIAEHPFDLLARARFRVTVNTDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKS 337
Query: 280 IFSEANIRELIIGKILK 296
F + R II +++K
Sbjct: 338 AFIPFDQRLAIIDEVIK 354
>UniRef50_UPI0000E4677B Cluster: PREDICTED: similar to Adenosine
deaminase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Adenosine deaminase -
Strongylocentrotus purpuratus
Length = 391
Score = 66.5 bits (155), Expect = 8e-10
Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 6/167 (3%)
Query: 117 HKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEV-LEMLNFK 175
H+ DTVVG++++G+ I A A GL T+H GE+ E V +
Sbjct: 210 HEFLNDTVVGVDMAGDEDASCTKQHIDAFRLAGDLGLHRTVHAGELGPAENVRFAVEQLG 269
Query: 176 PERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHF-KELIEAG 234
ERIGHG I+ + + + I +E+C TS++ T S H K + G
Sbjct: 270 AERIGHGYQIYQ----DPDIYKMIRDRFIHLELCPTSSIYTGAWKGKLSDHIAKRFAKDG 325
Query: 235 LSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
++ + TDD + ++ E++L F T Q+ ++L+AAQ F
Sbjct: 326 FNIGINTDDPTLLLNTMESEFQLAKTYFDFTDSQMKNMTLNAAQSCF 372
>UniRef50_Q1A7N0 Cluster: Adenosine deaminase; n=3; Schistosoma
japonicum|Rep: Adenosine deaminase - Schistosoma
japonicum (Blood fluke)
Length = 352
Score = 65.7 bits (153), Expect = 1e-09
Identities = 75/290 (25%), Positives = 131/290 (45%), Gaps = 35/290 (12%)
Query: 33 NLSECFQVFSIAHSLTS-TSEALVMATELTLQE-FQEDGCCYIELRSTP---RDTQYITK 87
+L + + F I L + E L E +++ Q G CY E R P D+++ +
Sbjct: 55 SLKDFLKAFEIIIPLIAGKKEVLARICEEFVEDCVQRGGLCYAETRYCPFLLADSRFNAE 114
Query: 88 ---KQYIDSIIRAMEA---------SQLQEVEEIADIAIERHKIH-PDTVVGIELSGNPA 134
K +DS+ RA + S ++ + E A +E K + P VV I+++G+ +
Sbjct: 115 EVLKTILDSLNRASKKHGIEVRSILSIMRHMPETASETLELAKNYQPHGVVAIDVAGDDS 174
Query: 135 VGNF----GDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNF-KPERIGHGVCIHPKY 189
V + + A+++G+ T+H GE V E +N ERIGHG I
Sbjct: 175 VLKSQRLPNEIVQTFEEAKKAGIHRTVHVGENSPASSVYEAVNILHAERIGHGYHILDD- 233
Query: 190 GGTEETWIALCQSKIPVEVC-----LTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDK 244
E+ + +L Q+ + EVC +T +V++KI ++ H F IE + + TDD
Sbjct: 234 ---EKAYKSLLQAGVHFEVCPSSSFVTGSVDSKILNNHPVHRF---IEDKANFSINTDDP 287
Query: 245 GVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKI 294
+ QE + C E+ + Q+ + +AA F + +E++I I
Sbjct: 288 TLTERWDIQEAQYCLETLGIKPSQLINANYNAAMSAFLTTSEKEILISHI 337
>UniRef50_UPI000058758F Cluster: PREDICTED: similar to Adenosine
deaminase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Adenosine deaminase -
Strongylocentrotus purpuratus
Length = 324
Score = 65.3 bits (152), Expect = 2e-09
Identities = 54/198 (27%), Positives = 97/198 (48%), Gaps = 27/198 (13%)
Query: 122 DTVVGIELSGNPAVGNFGDFIPAL--------------NRARQSGLKVTLHCGE---VCN 164
DTVVG++L+ N + + I A + A + + T H GE N
Sbjct: 132 DTVVGVDLANNEMLELYSQHINAFKLIGGDPHEIKVKKHGAEAASIHRTCHAGETGPARN 191
Query: 165 PEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSK-IPVEVCLTSNVNT-KITPDY 222
+ +E+L+ ERIGHG + +E+ + L + K I E+C TS+ T + D+
Sbjct: 192 VRDAIEVLH--AERIGHGYHVF-----DDESVVQLAKDKSIHFELCPTSSTRTGALEDDF 244
Query: 223 ESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFS 282
+ H K + G+++ + TDD +F T+LS+E+ + + F + +A ++L+ AQ F
Sbjct: 245 DKHCAKRFLSEGMNISINTDDPTLFGTTLSREFGIARKYFGMDDRALALMTLNTAQATFL 304
Query: 283 EANIRELIIGKIL-KFMN 299
+ + ++I + KF N
Sbjct: 305 PDDEKAVLIQSLRDKFKN 322
>UniRef50_Q54KF3 Cluster: Adenosine deaminase; n=1; Dictyostelium
discoideum AX4|Rep: Adenosine deaminase - Dictyostelium
discoideum AX4
Length = 772
Score = 65.3 bits (152), Expect = 2e-09
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 5/130 (3%)
Query: 144 ALNRARQSGLKVTLHCGEVCNPEEVLEMLNF-KPERIGHGVCIHPKYGGTEETWIALCQS 202
A + R G+ TLH GE N V + ++ RIGHG+ I EE +
Sbjct: 193 AFSIIRNKGINCTLHSGEDSNWTSVADSIHHCGAHRIGHGIAIQQN----EELLNHVVNR 248
Query: 203 KIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESF 262
+IP+E C+TSN K + H ++ ++G V +C D+ + +LS EY+L ++F
Sbjct: 249 RIPIECCITSNYQIKAISNASEHPIRKYFDSGAIVSICCDNCTMSNITLSGEYKLAIDTF 308
Query: 263 ALTRIQVAKL 272
+V +L
Sbjct: 309 NFKVEEVIRL 318
>UniRef50_P53984 Cluster: Adenosine deaminase; n=9; Bacteria|Rep:
Adenosine deaminase - Streptomyces virginiae
Length = 339
Score = 65.3 bits (152), Expect = 2e-09
Identities = 47/151 (31%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHG 182
+VG LS + G DF A AR+ GL H GE+ P V + L+ RIGHG
Sbjct: 166 IVGFGLSNDERRGMARDFDRAFAIAREGGLLAAPHGGELTGPSSVRDCLDDLHASRIGHG 225
Query: 183 VCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTD 242
V + L +I EVC SNV + E + L EAG+ + L D
Sbjct: 226 V----RAAEDPRLLKRLADRQITCEVCPASNVALGVYERPEDVPLRTLFEAGVPMALGAD 281
Query: 243 DKGVFATSLSQEYRLCAESFALTRIQVAKLS 273
D +F + L+ +Y + A T ++A+L+
Sbjct: 282 DPLLFGSRLAAQYEIARRHHAFTDTELAELA 312
>UniRef50_Q2JFM4 Cluster: Adenosine deaminase; n=3; Frankia|Rep:
Adenosine deaminase - Frankia sp. (strain CcI3)
Length = 360
Score = 64.9 bits (151), Expect = 2e-09
Identities = 46/138 (33%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 124 VVGIELSGNPAVGNFGD-FIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGH 181
VVGI L G P VG+ + F PA A GL H GE P V L+ RI H
Sbjct: 167 VVGIGLGG-PEVGHPPEPFAPAFALAADGGLAAVPHAGETAGPVSVRGALDALGARRIRH 225
Query: 182 GVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCT 241
G+ + E L I ++VC SN+ T+ + H L+ AG++ L T
Sbjct: 226 GI----RAAEDPELMRRLVDQGIVLDVCPVSNLRTRSVASLDDHPLAALLRAGVACSLAT 281
Query: 242 DDKGVFATSLSQEYRLCA 259
DD +F T L E+ + A
Sbjct: 282 DDPAMFGTDLETEHAVAA 299
>UniRef50_Q20YN2 Cluster: Adenosine deaminase; n=2;
Proteobacteria|Rep: Adenosine deaminase -
Rhodopseudomonas palustris (strain BisB18)
Length = 343
Score = 64.5 bits (150), Expect = 3e-09
Identities = 48/189 (25%), Positives = 81/189 (42%), Gaps = 9/189 (4%)
Query: 110 ADIAIERHKIHP--DTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEE 167
AD + +I P D ++ I + G F AR G + T+H GE
Sbjct: 147 ADAMVMLDQIMPWKDQIIAIGMGGAELGNPPAKFARFFKAARDRGFRTTVHAGEEGPAAY 206
Query: 168 VLEMLNF-KPERIGHG-VCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESH 225
V E L + +RI HG C+ + L +IP+ VC SN+ K + H
Sbjct: 207 VREALELLQVDRIDHGNACL-----ADPDLVRELAMRRIPLTVCPLSNLRLKGVTEMARH 261
Query: 226 HFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEAN 285
K ++ GL V + TDD F +++ C E+ L+R ++ +L + + F
Sbjct: 262 PLKTMMAQGLHVTVNTDDPPYFGGYVTENLLACREALDLSREEIVRLVRNGLEAAFVTTE 321
Query: 286 IRELIIGKI 294
RE+++ ++
Sbjct: 322 EREILLRQL 330
>UniRef50_Q86GS5 Cluster: Adenosine deaminase; n=9; Plasmodium|Rep:
Adenosine deaminase - Plasmodium falciparum
Length = 367
Score = 64.1 bits (149), Expect = 4e-09
Identities = 49/194 (25%), Positives = 91/194 (46%), Gaps = 14/194 (7%)
Query: 104 QEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGE-- 161
+ ++E A+ I+ H VG + +G+ + F + R+ G+ +++H GE
Sbjct: 182 ERMKEAAEFCIK----HKKDFVGYDHAGHEV--DLKPFKDIFDNIREEGISLSVHAGEDV 235
Query: 162 -VCNPEEVLEMLNF-KPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKIT 219
+ N + +N +RIGHG+ + ++E + + I +EVC SNV
Sbjct: 236 SIPNLNSLYTAINLLHVKRIGHGI----RVSESQELIDLVKEKDILLEVCPISNVLLNNV 291
Query: 220 PDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQC 279
++H + L +AG+ V + +DD G+F T+++ Y T K++L A Q
Sbjct: 292 KSMDTHPIRMLYDAGVKVSVNSDDPGMFLTNITDNYEELYTHLNFTLADFMKMNLWAVQK 351
Query: 280 IFSEANIRELIIGK 293
F + +I+ II K
Sbjct: 352 SFVDPDIKNKIISK 365
>UniRef50_A7SPK9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 262
Score = 63.7 bits (148), Expect = 6e-09
Identities = 28/81 (34%), Positives = 42/81 (51%)
Query: 160 GEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKIT 219
G V +E ++L +RIGHG C+HP GG++E + + IP+E+CL+SNV
Sbjct: 33 GYVPGAKEAKDLLELPTDRIGHGTCLHPDRGGSQELLDIVEKHAIPLELCLSSNVQCHTV 92
Query: 220 PDYESHHFKELIEAGLSVVLC 240
Y+ HH V+C
Sbjct: 93 SSYDDHHMWHWYNTNHPFVIC 113
>UniRef50_Q2JC46 Cluster: Adenosine deaminase; n=1; Frankia sp.
CcI3|Rep: Adenosine deaminase - Frankia sp. (strain
CcI3)
Length = 332
Score = 62.1 bits (144), Expect = 2e-08
Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 10/161 (6%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPE-RIGHG 182
V G++L+G+ V + A N A G+ VT+H GE PE V E L+ RIGHG
Sbjct: 168 VAGLDLAGDERVLG-ARHVEAFNLAHSQGIPVTVHAGEAVGPESVWEALDVLGAWRIGHG 226
Query: 183 VCIHPKYGGTEETWIA--LCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLC 240
V EE + L + +I +E C SNV T+ P +H + + +
Sbjct: 227 V------RSVEEAALLDRLRRDQIVLETCPRSNVLTRAVPALAAHPVARFLNEDIRATVN 280
Query: 241 TDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
TD + AT+L+ E A F + + L +AA+ F
Sbjct: 281 TDARTTAATTLTAELDSLAREFGWSDDEPELLCRNAAKGAF 321
>UniRef50_Q6IWY7 Cluster: Adenosine deaminase; n=1; Trichinella
spiralis|Rep: Adenosine deaminase - Trichinella spiralis
(Trichina worm)
Length = 346
Score = 62.1 bits (144), Expect = 2e-08
Identities = 46/181 (25%), Positives = 81/181 (44%), Gaps = 9/181 (4%)
Query: 118 KIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKP 176
K D VVGI+ +G +F A+ G+ T+H GEV + V + + +
Sbjct: 170 KFKKDGVVGIDQAGYV---HFPHEAKIFQMAKSRGIHRTVHAGEVGTADNVKQAIEQLQV 226
Query: 177 ERIGHGVCIHPKYGGTEETWIALCQSKIPVEVC-LTSNVNTKITPDYESHHFKELIEAGL 235
ERIGHG + E + E+C L+S V+ + D+ +H + ++ L
Sbjct: 227 ERIGHGYRVLQD----ESIYELAKNGGYHFELCPLSSVVSGSVVSDWSTHPARRFLKDQL 282
Query: 236 SVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKIL 295
+ + TDD + S+ E+ +C E T + + +AA+ F E + +E ++ I
Sbjct: 283 NFSINTDDPTILDNSMCSEFEICKEKLGFTETDLHVATCNAARSSFLEIDEKEQLLSNIK 342
Query: 296 K 296
K
Sbjct: 343 K 343
>UniRef50_UPI00006A2D02 Cluster: UPI00006A2D02 related cluster; n=2;
Xenopus tropicalis|Rep: UPI00006A2D02 UniRef100 entry -
Xenopus tropicalis
Length = 371
Score = 61.7 bits (143), Expect = 2e-08
Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 16/168 (9%)
Query: 123 TVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEML-NFKPERIGH 181
++V ++++G D + A A + + T+H GE PE + E + + ERIGH
Sbjct: 174 SIVALDIAGAERGYPAHDHVEAFAFAHKKFMHKTVHAGEGYGPESIFEAITDLHAERIGH 233
Query: 182 GVCIH-----PKYGGTEETWIALCQ--------SKIPVEVCLTSNVNT--KITPDYESHH 226
G+ + K ++ A C S+ +EVCL+SN+ T ++ D +H
Sbjct: 234 GLHLFRHDTIEKPDMDDKQRKAYCHDLVQYMGNSRTCLEVCLSSNLQTLPEMELDARNHP 293
Query: 227 FKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSL 274
++++ + L+V LCTD+ V T + +E RL ++F LT ++ ++ L
Sbjct: 294 LRDMLTSKLAVSLCTDNCTVSHTDMVREVRLACDAFQLTPHELRQILL 341
>UniRef50_Q4CZU3 Cluster: Putative uncharacterized protein; n=2;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 623
Score = 61.3 bits (142), Expect = 3e-08
Identities = 43/115 (37%), Positives = 58/115 (50%), Gaps = 19/115 (16%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSG-----------LKVTLHCGEVCNPEEVLEML 172
V G++ SG +F DF+PAL AR+ G L VTLH GE +PEE+ EM+
Sbjct: 342 VTGVDFSGYCGKNHFLDFLPALTEARRGGDGISTSPLYASLGVTLHAGEKDDPEELAEMV 401
Query: 173 NFKPERIGHGVCIHPKYGGTEETWI-ALCQSKIPVEVCLTSNVNTKITPDYESHH 226
F PER GH V T+ T + A+ +E+C+TSN T + HH
Sbjct: 402 KFAPERWGHLVY-------TDSTNLSAILARHDAIELCITSNAVTGGYTEVTQHH 449
>UniRef50_Q6F1Q1 Cluster: Adenosine deaminase; n=1; Mesoplasma
florum|Rep: Adenosine deaminase - Mesoplasma florum
(Acholeplasma florum)
Length = 334
Score = 60.9 bits (141), Expect = 4e-08
Identities = 50/210 (23%), Positives = 93/210 (44%), Gaps = 11/210 (5%)
Query: 87 KKQYIDSIIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALN 146
K + I ++ + + +++ +AIE KI VGI N F P ++
Sbjct: 129 KAKLIMCFLKDESVDEALNILDMSKLAIENKKI-----VGIGFDSNEIENWAAIFKPVVD 183
Query: 147 RARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHGVCIHPKYGGTEETWIALCQSKIP 205
+AR GL VT H E ++ +E++N P+RI HG+ IH E + + +I
Sbjct: 184 KARNLGLNVTTHAAENSFEQDPIEVINILNPDRIDHGLYIHKSL----EALKLVKEKEIH 239
Query: 206 VEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFA-TSLSQEYRLCAESFAL 264
+ +C N +K D ++ + ++ +S + +DD F T+L+ Y L ++ +
Sbjct: 240 LSLCPLPNFYSKAWLDPKTFPIQVFLDNDISFSINSDDPAYFGPTTLNDNYLLVNQNNKI 299
Query: 265 TRIQVAKLSLDAAQCIFSEANIRELIIGKI 294
+ + L L F+ +E + KI
Sbjct: 300 SEEKWKNLLLKTLNSTFTNTEEKEYLKEKI 329
>UniRef50_P00813 Cluster: Adenosine deaminase; n=32;
Euteleostomi|Rep: Adenosine deaminase - Homo sapiens
(Human)
Length = 363
Score = 60.1 bits (139), Expect = 7e-08
Identities = 54/179 (30%), Positives = 84/179 (46%), Gaps = 11/179 (6%)
Query: 118 KIHPDTVVGIELSGN---PAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNF 174
K TVV I+L+G+ P + A A +SG+ T+H GEV + E V E ++
Sbjct: 171 KYQQQTVVAIDLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDI 230
Query: 175 -KPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKI-TPDYESHHFKELIE 232
K ER+GHG H + + L Q + E+C S+ T PD E H L
Sbjct: 231 LKTERLGHGY--HTLED--QALYNRLRQENMHFEICPWSSYLTGAWKPDTE-HAVIRLKN 285
Query: 233 AGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF-SEANIRELI 290
+ L TDD +F ++L +Y++ T + +L+++AA+ F E REL+
Sbjct: 286 DQANYSLNTDDPLIFKSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELL 344
>UniRef50_Q8XXL5 Cluster: Adenosine deaminase; n=104; Bacteria|Rep:
Adenosine deaminase - Ralstonia solanacearum
(Pseudomonas solanacearum)
Length = 345
Score = 58.4 bits (135), Expect = 2e-07
Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 5/159 (3%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNF-KPERIGHG 182
++G+ L + F R + GL++ H GE + V++ L+ + ERI HG
Sbjct: 170 IIGVGLDSSERGNPPEKFARVFARCKALGLRLVAHAGEEGPAQYVIDALDILQVERIDHG 229
Query: 183 VCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTD 242
V + L S++ + VC SN K+ PD H K+L++AG +V L +D
Sbjct: 230 VRAIDDAALVKR----LAASRVALTVCPLSNEKLKVYPDLRDHSLKQLLDAGCAVTLHSD 285
Query: 243 DKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
D F ++ + + L+ L+ ++ + F
Sbjct: 286 DPAYFGGYMNTNWLATFNALGLSAADAHTLARNSFEASF 324
>UniRef50_Q0VNC2 Cluster: Putative uncharacterized protein; n=1;
Alcanivorax borkumensis SK2|Rep: Putative
uncharacterized protein - Alcanivorax borkumensis
(strain SK2 / ATCC 700651 / DSM 11573)
Length = 330
Score = 57.6 bits (133), Expect = 4e-07
Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Query: 121 PDTVVGIELSGNPAVGNFGDFIPALNRARQS-GLKVTLHCGEVCNPEEVLEML-NFKPER 178
P TVVG++L+GN + + + A+ LKVT+H GE E + + F +R
Sbjct: 166 PSTVVGLDLAGNENIESPIETGSLFLHAKDKYELKVTIHAGETGRVENITSAVYEFGADR 225
Query: 179 IGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVV 238
IGHG E L I VEVC SN T + + H + I + V
Sbjct: 226 IGHGTAASKSV----EVMDLLKHRDICVEVCPISNKLTSAVNESQPHPVVDFIANEVPFV 281
Query: 239 LCTDDKGVFATSLSQEY 255
+C+D+ + + L+++Y
Sbjct: 282 ICSDNPSIHLSDLTKDY 298
>UniRef50_Q64PK0 Cluster: Putative adenosine deaminase; n=1;
Bacteroides fragilis|Rep: Putative adenosine deaminase -
Bacteroides fragilis
Length = 507
Score = 57.2 bits (132), Expect = 5e-07
Identities = 44/161 (27%), Positives = 82/161 (50%), Gaps = 11/161 (6%)
Query: 145 LNRARQSGLKVTLHCGEVC----NPEEVLEMLNFK-----PERIGHGVCIHPKYGGTEET 195
L++A + +K +LH GE+ PE++ + +RIGHGV + + G
Sbjct: 329 LDKATGNRVKTSLHAGELTLGLVKPEDMCSHIREAVFVAGADRIGHGVDVAFEEGSIS-L 387
Query: 196 WIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEY 255
A+ + +IPVE+ LTSN + ++H F +A + VL TDD G+ T+L+Q+Y
Sbjct: 388 LDAMQKRQIPVEINLTSN-EFILGVKNDAHPFMLYRQAEVPTVLSTDDPGILRTNLAQQY 446
Query: 256 RLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKILK 296
L A + L ++ +L ++ + F ++ ++ ++ K
Sbjct: 447 VLAAMRYGLGYYEIKQLVRNSIRFGFMPEKEKQALLKRVEK 487
>UniRef50_Q4QHD0 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 728
Score = 57.2 bits (132), Expect = 5e-07
Identities = 41/121 (33%), Positives = 63/121 (52%), Gaps = 18/121 (14%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQ--------SGLKVT----LHCGEVCNPEEVLEM 171
V G++LSGN G + + PAL AR+ +G++VT +H GE +P+E+ EM
Sbjct: 376 VTGMDLSGNCYKGKYAELEPALAAARRGEVEEQDSNGIRVTASITIHAGEKQDPQELHEM 435
Query: 172 LNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELI 231
+ F PER GH V P A+ ++ +E+CLTSN+ T HH +L+
Sbjct: 436 VLFVPERWGHLVFTDP------ANLSAILTAQQGIELCLTSNMLTGGHSHVVDHHLGDLL 489
Query: 232 E 232
+
Sbjct: 490 Q 490
>UniRef50_Q9X7T2 Cluster: Probable adenosine deaminase 2; n=5;
Actinomycetales|Rep: Probable adenosine deaminase 2 -
Streptomyces coelicolor
Length = 359
Score = 56.8 bits (131), Expect = 6e-07
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 13/198 (6%)
Query: 106 VEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNP 165
V E AD+A+ VVG +++G D + A R+ + T+H GE
Sbjct: 159 VREAADLAVA---FRDAGVVGFDIAGAEDGFPPADHLDAFEHLRRENVPFTIHAGEAHGL 215
Query: 166 EEVLEMLNF-KPERIGHGVCIH---PKYG----GTEETWIALCQSKIPVEVCLTSNVNTK 217
+ + L +RIGHGV I P G W+ +I +E+C TSN+ T
Sbjct: 216 PSIHQALQVCGAQRIGHGVRITDDIPDLAAGKLGRLAAWVR--DRRIALEMCPTSNLQTG 273
Query: 218 ITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAA 277
H L + G V L TD++ V T++++E L E + + ++++A
Sbjct: 274 AATSIAEHPITALKDLGFRVTLNTDNRLVSGTTMTREMSLLVEQAGWSVEDLRTVTVNAL 333
Query: 278 QCIFSEANIRELIIGKIL 295
+ F + R +I ++
Sbjct: 334 KSAFVPFDERTALIEDVV 351
>UniRef50_UPI0000D558D4 Cluster: PREDICTED: similar to CG5992-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG5992-PA, isoform A - Tribolium castaneum
Length = 501
Score = 56.4 bits (130), Expect = 9e-07
Identities = 48/166 (28%), Positives = 74/166 (44%), Gaps = 15/166 (9%)
Query: 106 VEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPALNRARQSGLKVTLHCGEV-- 162
VE+ I E ++ PD V G +L G +G DFIP L ++ + H GE
Sbjct: 279 VEDYVTITKELRQLFPDFVAGFDLVGQEDLGKPLVDFIPQLLELAETDTRFFFHAGETDW 338
Query: 163 ---CNPEEVLEMLNFKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEVCLTSNVNTK 217
V + + RIGHG + HPK EE + + +I +E+ SN K
Sbjct: 339 GGTSTDLNVFDAVLLNTTRIGHGFALVKHPKI--LEE----VKKRQIAIEISPISNQVLK 392
Query: 218 ITPDYESHHFKELIEAGLSVVLCTDDKGVF-ATSLSQEYRLCAESF 262
+ D +H L+++G VV+ DD + A +LS ++ L F
Sbjct: 393 LVDDLRNHPGAFLVKSGFPVVITCDDPTFWGAKALSYDWYLAFMGF 438
>UniRef50_Q1FNG4 Cluster: Adenosine deaminase; n=1; Clostridium
phytofermentans ISDg|Rep: Adenosine deaminase -
Clostridium phytofermentans ISDg
Length = 315
Score = 56.4 bits (130), Expect = 9e-07
Identities = 33/127 (25%), Positives = 64/127 (50%), Gaps = 5/127 (3%)
Query: 140 DFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHGVCIHPKYGGTEETWIA 198
+F +A+ SGL++ H GE +V+E + + + + HG+ W+A
Sbjct: 174 NFKKIYRKAKDSGLRLKAHVGEFGTANDVMEAVEELELDEVHHGIAAVTS--PLIMKWLA 231
Query: 199 LCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLC 258
+++ + +C +SNV + Y+ H ++L + G+ V + TDD +F ++SQEY
Sbjct: 232 --DNRVQLNICPSSNVMLGVVKGYDVHPIRKLYDYGIPVTINTDDLLIFNQTVSQEYLNL 289
Query: 259 AESFALT 265
E+ +T
Sbjct: 290 YEAKLMT 296
>UniRef50_Q2J4I8 Cluster: Adenosine deaminase; n=3; Frankineae|Rep:
Adenosine deaminase - Frankia sp. (strain CcI3)
Length = 333
Score = 55.6 bits (128), Expect = 1e-06
Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 9/163 (5%)
Query: 141 FIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHGVCI--HPKYGGTEETWI 197
F+ A AR GL T H GE+ P V + +R+ HG+ P+ T
Sbjct: 170 FMAAFRIARDGGLLSTPHAGELDGPASVRGAIETLDADRLQHGIRAMEDPRLVDT----- 224
Query: 198 ALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRL 257
L + ++VC TSN+ + P H L+ AG+ + DD +F + +EY L
Sbjct: 225 -LLERGTCLDVCPTSNLLLSVVPSMAEHPLPALLRAGVRCSINADDPLLFGPTCLEEYEL 283
Query: 258 CAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKILKFMND 300
C + LT ++A + + + + +R + I ++ D
Sbjct: 284 CRSALGLTDEELAACARSSVESGAAPIEVRTAALAGIDAWLAD 326
>UniRef50_A0LRH8 Cluster: Adenosine deaminase; n=1; Acidothermus
cellulolyticus 11B|Rep: Adenosine deaminase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 356
Score = 55.6 bits (128), Expect = 1e-06
Identities = 48/172 (27%), Positives = 73/172 (42%), Gaps = 18/172 (10%)
Query: 99 EASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLH 158
EA + + E +A++ + VVG+ + G+ + A A GL V H
Sbjct: 140 EAYRGADPELVAEMVRYAGRYRDRGVVGVGIGGDERARPTRHYAAAFAPAVDLGLGVVPH 199
Query: 159 CGE----------VCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSK-IPVE 207
GE E +E LN P RI HG+ + +A+ + + I ++
Sbjct: 200 AGEFPLFPDGASGAATLRETIEALN--PVRIRHGIA-----AAADPALVAVIRERGIVLD 252
Query: 208 VCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCA 259
VC TSN+ T D H L AG+ + TDD VF T LS+E+ + A
Sbjct: 253 VCPTSNLRTGAIRDLADHPLPRLAAAGIPCTVGTDDPAVFDTDLSREFTIAA 304
>UniRef50_UPI0000D558D5 Cluster: PREDICTED: similar to Cat eye
syndrome critical region protein 1 homolog precursor;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cat
eye syndrome critical region protein 1 homolog precursor
- Tribolium castaneum
Length = 780
Score = 54.8 bits (126), Expect = 3e-06
Identities = 56/185 (30%), Positives = 82/185 (44%), Gaps = 22/185 (11%)
Query: 81 DTQYITKKQYIDSIIRAMEASQLQE-VEEIADIAIERHKIHPDTVVGIELSGNPAVG-NF 138
D T +YI SI R +E L+ +EEI IE K HPD + G + G G
Sbjct: 551 DFPAFTGAKYIHSIYRGVENDVLKTALEEI----IELRKHHPDLIAGFDFVGFEEEGCTL 606
Query: 139 GDFIPALNRARQSGLKVTLHCGEVC----NPEEVLEMLNFKPERIGHGVCI--HPKYGGT 192
D+ L A + L H GE +L+ + RIGHG + HPK
Sbjct: 607 FDYHLLLLEAGKH-LNFFFHAGETNWFGHTDLNLLDAILLNTSRIGHGFALVKHPKM--- 662
Query: 193 EETWIALCQSK-IPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVF-ATS 250
+ L +S+ I +E+C SN + D+ +H L+ G VV+ DD ++ AT
Sbjct: 663 ----LQLAKSRNIALEICPISNQVLMLNQDHRNHPAAVLMALGFPVVIGNDDPSIWDATG 718
Query: 251 LSQEY 255
LS ++
Sbjct: 719 LSYDW 723
>UniRef50_UPI00006601DD Cluster: Adenosine deaminase (EC 3.5.4.4)
(Adenosine aminohydrolase).; n=2; Clupeocephala|Rep:
Adenosine deaminase (EC 3.5.4.4) (Adenosine
aminohydrolase). - Takifugu rubripes
Length = 366
Score = 54.4 bits (125), Expect = 3e-06
Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 25/199 (12%)
Query: 118 KIHPDTVVGIELSGNPAVGNFG--DFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-F 174
K + VV I+L+G+ ++ + D A A + G+ T+H GEV P V E +
Sbjct: 160 KYQHEGVVAIDLAGDESLSSEANPDHRRAYEEAARCGVHRTVHAGEVGPPSVVKEAVEVL 219
Query: 175 KPERIGHGV---------------CIHPKYGGT-----EETWIALCQSKIPVEVC-LTSN 213
K ER+GHG +H + G+ W +P +VC ++S
Sbjct: 220 KAERVGHGYRTLEDQSLYRKLLAQNMHFEVRGSLNLSGRRCWADCAVLLLPQQVCPISSK 279
Query: 214 VNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLS 273
+ PD+ H + + L TDD +F +SL +Y + ++ T + +L+
Sbjct: 280 LTGACDPDFTKHPVITFRKDKANYSLNTDDPLIFNSSLHLDYSVASKYMGFTEQEFKRLN 339
Query: 274 LDAAQ-CIFSEANIRELII 291
++AA+ C E +EL+I
Sbjct: 340 INAAESCFLPEKEKQELLI 358
>UniRef50_Q0YRQ4 Cluster: Adenosine/AMP deaminase precursor; n=1;
Chlorobium ferrooxidans DSM 13031|Rep: Adenosine/AMP
deaminase precursor - Chlorobium ferrooxidans DSM 13031
Length = 493
Score = 54.4 bits (125), Expect = 3e-06
Identities = 43/145 (29%), Positives = 76/145 (52%), Gaps = 11/145 (7%)
Query: 153 LKVTLHCGEVCN----PEE----VLEMLNFK-PERIGHGVCIHPKYGGTEETWIALCQSK 203
++ ++H GE+ + PEE + E ++ RIGHGV I + G T + + + +
Sbjct: 327 IRTSMHAGELASGMVPPEELKYHIAEAVSVAGAARIGHGVDIAYETGALS-TLMRMKEDR 385
Query: 204 IPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFA 263
IPVE+ LTSN D E+H + +G+ VV+ +DD GV SL++EY L A +
Sbjct: 386 IPVEINLTSNEFILGIKD-EAHPVRLYTGSGVPVVISSDDPGVSRNSLTEEYVLLASRYR 444
Query: 264 LTRIQVAKLSLDAAQCIFSEANIRE 288
+ +V + + ++ F + + +E
Sbjct: 445 YSYDEVKQFAANSIIYSFLKKDEKE 469
>UniRef50_Q57W08 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma brucei|Rep: Putative uncharacterized protein
- Trypanosoma brucei
Length = 617
Score = 54.0 bits (124), Expect = 5e-06
Identities = 37/122 (30%), Positives = 59/122 (48%), Gaps = 18/122 (14%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQ------------SGLKVTLHCGEVCNPEEVLEM 171
V G++ SG +F +F+PAL+ R+ S L +T+H GE + E+ E+
Sbjct: 311 VTGMDFSGYCGKNSFTEFVPALSEVRRGRDGNGGVVTNRSPLGITIHAGEKPDTAELTEI 370
Query: 172 LNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELI 231
+ F P+R GH V P T + P+E+CL+SN+ T E HH +++
Sbjct: 371 VGFAPDRWGHLVFTDPANLKT------ITARYDPIELCLSSNLLTGGYSSVEKHHLTQIM 424
Query: 232 EA 233
A
Sbjct: 425 SA 426
>UniRef50_Q2H9J1 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 445
Score = 54.0 bits (124), Expect = 5e-06
Identities = 67/272 (24%), Positives = 112/272 (41%), Gaps = 44/272 (16%)
Query: 38 FQVFS-IAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPR--DTQYITKKQYIDSI 94
F +FS ++L + + L T L++F DG Y+ELR+TPR +T+ Y+ +I
Sbjct: 174 FPLFSSYIYNLVNNAATLRYTTLAVLRDFAADGVVYLELRTTPRAMPAAGLTEAGYVQTI 233
Query: 95 IRAMEASQLQEVEEIADIAIERHKI------HPDT----------------VVGIELSGN 132
+ + + + + + I H T VVGI+L G
Sbjct: 234 LDGIAEYEREPPRSENGVGLRTKLILSIDRRHAPTQAARVLALAKQFLGRGVVGIDLCGE 293
Query: 133 PAVGNFGDFIPALN-RARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKY-- 189
PA + P+ + Q+G+ + L + + E+ +L ++P+RIGH +C+ +
Sbjct: 294 PATPLDPELSPSREAKPGQAGMTLHLPSRVLASDAELDTLLGWRPDRIGHVICVSDRVRR 353
Query: 190 GGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFAT 249
G E W + +P LT HF ++E + + VF +
Sbjct: 354 GDYGEAWDRV--GAVPQLGMLT-----------RRSHFVGVVE---DTGDGSGTERVFES 397
Query: 250 SLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
LS EY L A+ F L R Q+ L IF
Sbjct: 398 PLSNEYALVAQHFGLDRSQICALVRRGVDIIF 429
>UniRef50_UPI000038CB1B Cluster: COG1816: Adenosine deaminase; n=1;
Nostoc punctiforme PCC 73102|Rep: COG1816: Adenosine
deaminase - Nostoc punctiforme PCC 73102
Length = 523
Score = 53.6 bits (123), Expect = 6e-06
Identities = 43/142 (30%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 153 LKVTLHCGEVCNPEEVLEMLNF---------KPERIGHGVCIHPKYGGTEETWIALCQSK 203
+KV LH GE+ E L F + RIGHGV I + E + +
Sbjct: 325 VKVALHSGELTLGLVPTEDLRFHIRQAVEVAQASRIGHGVDILFEERPFE-LMEQMRRLG 383
Query: 204 IPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFA 263
+ VE+CLTSN + + H F+E +AG+ + L +DD+G+ LS EY L A +
Sbjct: 384 VLVEICLTSN-EVILNVQGDQHPFREYWKAGVPMTLASDDEGISRIDLSHEYLLAATRYG 442
Query: 264 LTRIQVAKLSLDAAQCIFSEAN 285
L + +L+ ++ + F+ N
Sbjct: 443 LGYKDLKRLARNSLEYSFAPGN 464
>UniRef50_Q17747 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 391
Score = 53.6 bits (123), Expect = 6e-06
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 9/156 (5%)
Query: 140 DFIPALNRARQSGLKVTLHCGEVCNPEEVLEML-NFKPERIGHGVCIHPKYGGTEETWIA 198
+ + A A + G+ T+H GE P+EV++ + + ERIGHG + EE ++
Sbjct: 229 EVVAAFQEAHKRGIHRTVHAGESGGPKEVIKAIEDMYAERIGHGY----RVMRDEEMYLE 284
Query: 199 -LCQSK-IPVEVCLTSNVNTKITP-DYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEY 255
SK + +E C S+V T P D+++H + ++ + DD F S+ E
Sbjct: 285 HFVNSKNVHLEACPYSSVMTGAVPLDWKNHPIARWAKDDVNFSVSRDDPTCFDNSMLSEL 344
Query: 256 RLCAESFALTRIQVAKLSLDAAQ-CIFSEANIRELI 290
L + L Q+ K L+AA+ C E EL+
Sbjct: 345 TLVHKQIGLDVHQLWKAQLNAARSCFLPEDEKAELV 380
>UniRef50_Q2JAE3 Cluster: Adenosine/AMP deaminase; n=1; Frankia sp.
CcI3|Rep: Adenosine/AMP deaminase - Frankia sp. (strain
CcI3)
Length = 308
Score = 52.8 bits (121), Expect = 1e-05
Identities = 39/156 (25%), Positives = 76/156 (48%), Gaps = 9/156 (5%)
Query: 105 EVEEIADIAIERHKIHPDTVVGIELSGNPA-VGNFGDFIPALNRARQSGLKVTLHCGEVC 163
+++ + D+ E+ + + G++L+ P + F ++ L + G+KV +H GE+
Sbjct: 136 QLDALFDVLSEQDDL-TTRIAGVDLNFLPYDLPKFNRYLRTLRNLQTGGMKVNIHLGELF 194
Query: 164 NPEEVLEML-NFKPERIGHGVCIHPKYGGTEETWIALCQSK-IPVEVCLTSNVNTKITPD 221
N +L P+RIGHGV + +E + ++ I +++C TSN +
Sbjct: 195 NNAISHYVLARITPDRIGHGVLLLD-----DEALVDFVRANGICLDMCPTSNTLLGVADW 249
Query: 222 YESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRL 257
+ + ++ G+ V + TDD +F TSL E+ L
Sbjct: 250 NRTSPARVALQLGIPVSINTDDPVLFRTSLESEFSL 285
>UniRef50_Q9NZK5 Cluster: Cat eye syndrome critical region protein 1
precursor; n=32; Euteleostomi|Rep: Cat eye syndrome
critical region protein 1 precursor - Homo sapiens
(Human)
Length = 511
Score = 52.8 bits (121), Expect = 1e-05
Identities = 41/144 (28%), Positives = 63/144 (43%), Gaps = 13/144 (9%)
Query: 121 PDTVVGIELSGNPAVGN-FGDFIPALNRARQSGLKVT--LHCGEV-----CNPEEVLEML 172
P V G +L G+ G+ D+ AL + G+K+ H GE +L+ L
Sbjct: 316 PTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILDAL 375
Query: 173 NFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIE 232
RIGHG + +W + IP+EVC SN K+ D +H L+
Sbjct: 376 MLNTTRIGHGFALSKHPAVRTYSW----KKDIPIEVCPISNQVLKLVSDLRNHPVATLMA 431
Query: 233 AGLSVVLCTDDKGVF-ATSLSQEY 255
G +V+ +DD +F A LS ++
Sbjct: 432 TGHPMVISSDDPAMFGAKGLSYDF 455
>UniRef50_A7HDC2 Cluster: Adenosine deaminase; n=3;
Myxococcaceae|Rep: Adenosine deaminase -
Anaeromyxobacter sp. Fw109-5
Length = 332
Score = 52.4 bits (120), Expect = 1e-05
Identities = 40/143 (27%), Positives = 66/143 (46%), Gaps = 9/143 (6%)
Query: 147 RARQSGLKVTLHCGEVC--NPEEVLEML-NFKPERIGHGVCIHPKYGGTEETWIALCQSK 203
RAR +GLK T+H GE E V ++ +P+RIGHG+C E L +
Sbjct: 193 RARAAGLKTTVHTGETAGTGAEGVRAVVEELQPQRIGHGICA----AKDERVMDLLRERG 248
Query: 204 IPVEVCLTSNVNTKITP--DYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAES 261
+ +E+C +SN+ T+ D + + G+ + TD + T++ E RL +
Sbjct: 249 VVLEICPSSNLATRAVASLDELGEVLRRFWQRGVKFTINTDGPYLLDTNMRSEVRLLRDG 308
Query: 262 FALTRIQVAKLSLDAAQCIFSEA 284
L+ Q+ + A + F EA
Sbjct: 309 GILSDEQLDQTQEWAREATFVEA 331
>UniRef50_A5IHA0 Cluster: Adenosine deaminase; n=4; Legionella
pneumophila|Rep: Adenosine deaminase - Legionella
pneumophila (strain Corby)
Length = 491
Score = 52.0 bits (119), Expect = 2e-05
Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 155 VTLHCGEVC----NPEEVLE-----MLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIP 205
+TLH GE+ PE + +L +RIGHGV I + E+T + IP
Sbjct: 304 ITLHAGELSPQAVTPENLSNHIRDALLIGHAQRIGHGVDIGYE-NNAEDTLKYMASHHIP 362
Query: 206 VEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALT 265
VE+ L SN+ + +H + + VVL TDD+GV T L+Q+Y A+ L
Sbjct: 363 VEINLISNLKI-LNISGRNHPLNYYLTHNVPVVLSTDDEGVLRTDLTQQYVEAAKEHGLN 421
Query: 266 RIQVAKLS 273
Q+ +++
Sbjct: 422 YQQLKQIN 429
>UniRef50_Q1YXC1 Cluster: Adenosine deaminase; n=1; Photobacterium
profundum 3TCK|Rep: Adenosine deaminase - Photobacterium
profundum 3TCK
Length = 371
Score = 51.6 bits (118), Expect = 2e-05
Identities = 48/169 (28%), Positives = 78/169 (46%), Gaps = 18/169 (10%)
Query: 120 HPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVC----NPEEVLEMLNFK 175
HP ++GI + + F A A Q ++T HC E N E +E++N
Sbjct: 169 HP-YILGIGIDYKEHNASVEKFWKAYRLAEQHHYRLTAHCSEFGLHWRNVETGIELINI- 226
Query: 176 PERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDY----ESHHFKELI 231
ERI HG I TE+ Q +P V ++ K P++ + H + +
Sbjct: 227 -ERIDHGYTIIDNPELTEK----YAQKGVPFTVIPSNTYYFKQWPEHKDWCQKHPIRAMA 281
Query: 232 EAGLSVVLCTDDKGVFATSLSQEYRLCAESFA--LTRIQVAKL-SLDAA 277
+AGL+++ CTDD + T+ + YR+ E F L ++V L S+DA+
Sbjct: 282 KAGLNIIPCTDDWHIHNTTSANCYRVMVEDFGFDLDSLRVMMLNSIDAS 330
>UniRef50_Q2FRB2 Cluster: Adenosine/AMP deaminase; n=1;
Methanospirillum hungatei JF-1|Rep: Adenosine/AMP
deaminase - Methanospirillum hungatei (strain JF-1 / DSM
864)
Length = 483
Score = 51.2 bits (117), Expect = 3e-05
Identities = 31/78 (39%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Query: 178 RIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSV 237
RIGHGV I + G E T + + IPVE+ LTSN + H + + V
Sbjct: 356 RIGHGVAIQEEEG-FENTLAIMREKDIPVEILLTSNEQI-LNISGPEHPVAVYLANDVPV 413
Query: 238 VLCTDDKGVFATSLSQEY 255
+L TDD GV T+L+QEY
Sbjct: 414 ILATDDPGVECTNLTQEY 431
>UniRef50_UPI000023D260 Cluster: hypothetical protein FG06422.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG06422.1 - Gibberella zeae PH-1
Length = 648
Score = 50.8 bits (116), Expect = 4e-05
Identities = 43/166 (25%), Positives = 77/166 (46%), Gaps = 20/166 (12%)
Query: 104 QEVEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPALNRARQS----GLKVTL- 157
+++E + K+ P+ + G +L G A G DFIP L R +++ G+++
Sbjct: 420 EQIEGALTECLAFKKLWPEWIAGFDLVGEEAKGRPIKDFIPELLRFQENCASEGVEIPFL 479
Query: 158 -HCGEVCN-----PEEVLEMLNFKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEVC 209
HCGE + +++ L K +RIGHG + HP Y +C +E+C
Sbjct: 480 FHCGETLDMGTDTDGNLIDALLLKSKRIGHGFALAKHP-YVMQHMKERGVC-----LELC 533
Query: 210 LTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEY 255
SN +TP H +L+ + + +D+ +F +SLS ++
Sbjct: 534 PISNEILGLTPRVSGHAMYQLLANNVHCTVSSDNGTLFRSSLSHDF 579
>UniRef50_O83085 Cluster: Adenosine deaminase; n=2; Treponema|Rep:
Adenosine deaminase - Treponema pallidum
Length = 299
Score = 50.4 bits (115), Expect = 6e-05
Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 7/130 (5%)
Query: 127 IELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHGVCI 185
I+L G DFI A + LK H GE + + V + F + + HG+
Sbjct: 153 IDLYGPEISEGIEDFIYIFKLAEKYHLKKKAHVGEFSDAQSVRHFVEIFNLDEVQHGIG- 211
Query: 186 HPKYGGTEETWIA-LCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDK 244
T+E + L + K+ VC TSNV E H K++++AG+ V L TDD
Sbjct: 212 ----AATDENVLRFLAERKVRCNVCPTSNVMLNAVECLEKHPIKKMMDAGVRVGLGTDDL 267
Query: 245 GVFATSLSQE 254
F + S++
Sbjct: 268 LFFGKTNSEQ 277
>UniRef50_A6WE69 Cluster: Adenosine deaminase; n=1; Kineococcus
radiotolerans SRS30216|Rep: Adenosine deaminase -
Kineococcus radiotolerans SRS30216
Length = 336
Score = 50.0 bits (114), Expect = 7e-05
Identities = 41/134 (30%), Positives = 56/134 (41%), Gaps = 5/134 (3%)
Query: 141 FIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHGVCIHPKYGGTEETWIAL 199
F A AR +GL V H G+ E V E L+ RI HGV L
Sbjct: 178 FAAAAAAARAAGLPVVAHAGQTGGWECVAEALDVLGATRISHGVRSVENPAFVRR----L 233
Query: 200 CQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCA 259
+ + +V SNV I PD SH L AG+ + L DD+ F +S +Y +
Sbjct: 234 VEEGVVCDVAPVSNVALGIVPDLASHPAPALHAAGVGITLNADDQLWFGRGVSDQYAVAR 293
Query: 260 ESFALTRIQVAKLS 273
E + L +A L+
Sbjct: 294 EVWGLADEDLAALA 307
>UniRef50_Q7N3E5 Cluster: Similar to adenosine deaminase; n=1;
Photorhabdus luminescens subsp. laumondii|Rep: Similar
to adenosine deaminase - Photorhabdus luminescens subsp.
laumondii
Length = 335
Score = 49.6 bits (113), Expect = 1e-04
Identities = 45/180 (25%), Positives = 76/180 (42%), Gaps = 11/180 (6%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHG 182
VV ++L+ + A + A ++G + H GE E V E +N RIGHG
Sbjct: 158 VVALDLAADEARYPLSAHLNAFRMVLENGGNIIAHAGEAKGAESVRETINKLNISRIGHG 217
Query: 183 VCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDY------ESHHFKELIEAGLS 236
V + + L + I +EVC T N+ I Y E+H L E G++
Sbjct: 218 V----RSIEDRDVIELLIERNIHLEVCPTCNIICDIYDIYDIYDIYENHPVNFLKEVGVN 273
Query: 237 VVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKILK 296
+ + TD + V +L +EY F + +L+A FS ++ + +I++
Sbjct: 274 IGINTDARTVANITLCEEYLRINRYFGWQYSDFIETNLNALHASFSSNELKSRLEKEIMR 333
>UniRef50_A3VU86 Cluster: Adenosine deaminase; n=1; Parvularcula
bermudensis HTCC2503|Rep: Adenosine deaminase -
Parvularcula bermudensis HTCC2503
Length = 517
Score = 49.6 bits (113), Expect = 1e-04
Identities = 45/139 (32%), Positives = 64/139 (46%), Gaps = 19/139 (13%)
Query: 156 TLHCGEVCNPEEVLEMLNF---------KPERIGHGVCIHPKYGGTEETWIALCQSK--- 203
TLH GE+ + LE + + + RIGHGV I G E AL Q
Sbjct: 330 TLHAGELWSGLTELEDMTYHIREAVDVARARRIGHGVGI-----GYETDAPALLQQMADQ 384
Query: 204 -IPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESF 262
+ VE+ LTSN + + H + G+ +VL TDD+GV L+ EY+L AE +
Sbjct: 385 GVTVEINLTSN-EVILGVKGDQHPITTYRQFGVPIVLSTDDEGVLRNDLTTEYQLAAERY 443
Query: 263 ALTRIQVAKLSLDAAQCIF 281
L+ + LS + Q F
Sbjct: 444 DLSYEDLKTLSRQSLQSSF 462
>UniRef50_A0JTD4 Cluster: Adenosine deaminase; n=2; Bacteria|Rep:
Adenosine deaminase - Arthrobacter sp. (strain FB24)
Length = 378
Score = 49.6 bits (113), Expect = 1e-04
Identities = 44/190 (23%), Positives = 79/190 (41%), Gaps = 7/190 (3%)
Query: 107 EEIADIAIERHKIHPDTVVGIELSGNPAVGNF-GDFIPALNRARQSGLKVTLHCGEVCNP 165
EE A +E+ + GI L + VGN F RA+++GL H GE P
Sbjct: 191 EEAALDVLEQLLAMNAPIAGIGLD-SAEVGNPPAKFERLFARAKEAGLHRIAHAGEEGPP 249
Query: 166 EEVLEMLNFKP-ERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYES 224
+++ L ERI HG+ E L ++P+ VC SNV +
Sbjct: 250 SYIIDALELLDVERIDHGIRCMEDPDLVEH----LVAERVPLTVCPLSNVRLRAVDTLAE 305
Query: 225 HHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEA 284
H ++ AGL+V + +DD F + + L+ +L+ ++ + F++
Sbjct: 306 HPLPAMLAAGLNVSVNSDDPAYFGGYVDDNFVQLQTVLGLSEFDRVRLASNSIRSSFADE 365
Query: 285 NIRELIIGKI 294
+ ++ ++
Sbjct: 366 ERKTELLAEL 375
>UniRef50_A6W9Q9 Cluster: Adenosine deaminase; n=1; Kineococcus
radiotolerans SRS30216|Rep: Adenosine deaminase -
Kineococcus radiotolerans SRS30216
Length = 351
Score = 49.2 bits (112), Expect = 1e-04
Identities = 55/196 (28%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 100 ASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHC 159
A+ LQ VEE+ IA R + V+G+ L + A+G F A A ++GL T H
Sbjct: 151 AAGLQLVEEV--IADRREE-----VLGVGLDYSEAIGPPEKFWRAFALAGRAGLHRTAHS 203
Query: 160 --GEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQS-KIPVEVC-LTSNVN 215
G + E +L++L ERI HG + + A C S +IP ++S++
Sbjct: 204 ESGPPHHVETILDLLG--GERIDHGYHVVD-----DPDLTARCVSERIPFTCTPVSSDIG 256
Query: 216 TKITPDYESHH-FKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSL 274
+HH +E+++AGL V + +DD +F T + +YR+ A + ++A+ +
Sbjct: 257 RYSGSGDGTHHRIREMVDAGLCVTIDSDDPPMFGTDPTHDYRVLARALGYGLDELAQFTR 316
Query: 275 DAAQ-CIFSEANIREL 289
+A C E++ + L
Sbjct: 317 NAVDGCWLDESDKQTL 332
>UniRef50_A4ADQ6 Cluster: Adenosine deaminase; n=1; Congregibacter
litoralis KT71|Rep: Adenosine deaminase - Congregibacter
litoralis KT71
Length = 346
Score = 49.2 bits (112), Expect = 1e-04
Identities = 34/143 (23%), Positives = 58/143 (40%), Gaps = 5/143 (3%)
Query: 140 DFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNF-KPERIGHGVCIHPKYGGTEETWIA 198
+F A++ G ++T H GE + + L K RI HGV + +
Sbjct: 187 NFQTLYREAKKRGYELTAHAGEEGPASFIRDALQLLKVTRIDHGV----RAVDDADLLQQ 242
Query: 199 LCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLC 258
L ++P+ VC SNV + H +L+E GL + + +DD F L + +
Sbjct: 243 LAADRVPLTVCPLSNVRLCVYDSLSEHRIFDLLEQGLCITVNSDDPAYFGGDLLENFAAL 302
Query: 259 AESFALTRIQVAKLSLDAAQCIF 281
++R Q L + + F
Sbjct: 303 ESELDMSREQAVMLVRNGFEAAF 325
>UniRef50_Q0RQP4 Cluster: Putative adenosine deaminase 3; n=1;
Frankia alni ACN14a|Rep: Putative adenosine deaminase 3
- Frankia alni (strain ACN14a)
Length = 382
Score = 48.4 bits (110), Expect = 2e-04
Identities = 38/156 (24%), Positives = 63/156 (40%), Gaps = 6/156 (3%)
Query: 122 DTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIG 180
+ V+G+ + + F A A + GL+ T H GE P + +++ ER+
Sbjct: 192 ERVLGVGMDSTERGVDPASFADAYRLAARHGLRRTGHQGENSPPTAIATLVDVLGAERVD 251
Query: 181 HGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVN-TKITPDYESHHFKELIEAGLSVVL 239
HG+ + E +IP+ VC SN+ P H + + GL L
Sbjct: 252 HGLSLVDD----PELMTRFAAERIPLTVCPNSNIRIANAFPALADHPYPAMRAGGLLATL 307
Query: 240 CTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLD 275
TDD + L EY A +F + + ++LD
Sbjct: 308 NTDDPALTDLDLGYEYASVATAFDYSFDDMVAIALD 343
>UniRef50_Q4FWQ3 Cluster: Adenosine deaminase, putative; n=4;
Leishmania|Rep: Adenosine deaminase, putative -
Leishmania major strain Friedlin
Length = 362
Score = 48.4 bits (110), Expect = 2e-04
Identities = 38/147 (25%), Positives = 67/147 (45%), Gaps = 8/147 (5%)
Query: 158 HCGEVCNPEEVLEMLNF-KPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNT 216
H GE PE + + ++ K +RI HGV ++ L + +IP+ VC TSNV
Sbjct: 213 HAGEEGPPEYMRDAMSMLKVDRIDHGVAARLDQALCKD----LREKRIPLTVCPTSNVAL 268
Query: 217 KITPDYESHH---FKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLS 273
K+ D + ++ GL V + +DD F + + +R+ AE+ LT + +L
Sbjct: 269 KVFQDRATCGAVVMDLILTEGLCVTINSDDPAYFGGDIRESFRILAETGRLTPATLKQLV 328
Query: 274 LDAAQCIFSEANIRELIIGKILKFMND 300
L++ F + + ++ K D
Sbjct: 329 LNSFSSSFIADDSKRAYKERVEKVFKD 355
>UniRef50_A6M8U8 Cluster: Adenosine deaminase-related growth
factor-like protein; n=1; Mamestra brassicae|Rep:
Adenosine deaminase-related growth factor-like protein -
Mamestra brassicae (Cabbage armyworm)
Length = 498
Score = 48.4 bits (110), Expect = 2e-04
Identities = 44/159 (27%), Positives = 75/159 (47%), Gaps = 16/159 (10%)
Query: 106 VEEIADIAIERHKIHPDTVVGIELSGNPAVG-NFGDFIPALNRARQSGLKVTLHCGEV-- 162
++E IA+ + PD +VG +L G +G +F L R+S L + LH GE
Sbjct: 291 LKEYIRIALLIQALMPDFLVGFDLVGQEDLGVPLKEFAHELAEVRES-LDLYLHAGETNW 349
Query: 163 ---CNPEEVLEMLNFKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEVCLTSNVNTK 217
+ E + + + +RIGH + HP EE + + +I +EV + SN K
Sbjct: 350 YGTSSDENLFDAIVLGAKRIGHAFALIKHPLL--MEE----VKKRQIALEVNVVSNSVLK 403
Query: 218 ITPDYESHHFKELIEAGLSVVLCTDDKGVF-ATSLSQEY 255
+ D +H + + VVL +DD G++ A +S ++
Sbjct: 404 LVEDPRNHPLANFLSQNMPVVLSSDDPGIWEALPMSHDF 442
>UniRef50_A1CUF8 Cluster: CECR1 family adenosine deaminase,
putative; n=5; Pezizomycotina|Rep: CECR1 family
adenosine deaminase, putative - Aspergillus clavatus
Length = 574
Score = 47.6 bits (108), Expect = 4e-04
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 16/145 (11%)
Query: 114 IERHKIHPDTVVGIELSGNPAVGN-FGDFIPAL----NRARQSGLKVTL--HCGEVCNPE 166
IE +PD + G ++ G +G D +P L R + G+ + H GE
Sbjct: 343 IETKLAYPDVICGFDVVGQEDLGRPLVDLVPVLFWFRKRCVEEGVNIPFFFHAGECLGDG 402
Query: 167 E-----VLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPD 221
+ + + + RIGHG ++ K+ + + + KI +E C SN ++T
Sbjct: 403 DQTDHNLFDAILLGTRRIGHGFSLY-KHPLLVDL---VKEKKILIECCPISNEILRLTSS 458
Query: 222 YESHHFKELIEAGLSVVLCTDDKGV 246
+SH L+ G+SV LC DD +
Sbjct: 459 IKSHPLPALLARGVSVSLCNDDPAI 483
>UniRef50_Q5NPT1 Cluster: Adenosine deaminase; n=1; Zymomonas
mobilis|Rep: Adenosine deaminase - Zymomonas mobilis
Length = 526
Score = 47.2 bits (107), Expect = 5e-04
Identities = 39/138 (28%), Positives = 63/138 (45%), Gaps = 11/138 (7%)
Query: 153 LKVTLHCGEVCNP-------EEVLEMLNFKP--ERIGHGVCIHPKYGGTEETWIALCQSK 203
+K+TLH GE+ P + + F +RIGHG+ I + E + +
Sbjct: 327 VKITLHAGELALPLVPTAGLRDHIRKAVFVAGADRIGHGIDIGSEMNPVEILH-HMAERP 385
Query: 204 IPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFA 263
+PVE+ L+SN + + H F + + VV+ TDD GV L+ EY E
Sbjct: 386 VPVEINLSSN-DAILNIKGNQHPFALYRQYNVPVVISTDDAGVSRNDLTTEYMRAIEEQH 444
Query: 264 LTRIQVAKLSLDAAQCIF 281
++ + KLS D+ + F
Sbjct: 445 VSYSDLKKLSRDSLEYAF 462
>UniRef50_Q14HR2 Cluster: Adenosine deaminase; n=7; Francisella
tularensis|Rep: Adenosine deaminase - Francisella
tularensis subsp. tularensis (strain FSC 198)
Length = 314
Score = 47.2 bits (107), Expect = 5e-04
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 9/153 (5%)
Query: 122 DTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGE-VCNPEEVLEMLNFKPERIG 180
D +GI L G F A++ GL +T H E V E +++L RI
Sbjct: 159 DRFIGIGLDGYEFGNPPSKFKKLFEIAKKEGLYLTTHVSEPVEYIWEAIDVLGVN--RID 216
Query: 181 HGVCIHPKYGGTEETWIA-LCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVL 239
HG I +ET I + + IP+ +C S+ K + S L+E G+ V +
Sbjct: 217 HGNSILE-----DETLIQRVIKDNIPLTMCPLSDKFLKTNSNLSSRPVGILLEKGVKVTI 271
Query: 240 CTDDKGVFATSLSQEYRLCAESFALTRIQVAKL 272
+DD F+ +++ YR +++ L+ Q+ KL
Sbjct: 272 NSDDPAYFSGYINENYRQISQALKLSEDQIIKL 304
>UniRef50_A3H9U3 Cluster: Adenosine deaminase; n=1; Caldivirga
maquilingensis IC-167|Rep: Adenosine deaminase -
Caldivirga maquilingensis IC-167
Length = 348
Score = 47.2 bits (107), Expect = 5e-04
Identities = 42/174 (24%), Positives = 73/174 (41%), Gaps = 7/174 (4%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-FKPERIGHG 182
++GI L F A A +GL H GE E V E +N RI HG
Sbjct: 167 IIGICLDSKEYGNPPSKFRNAYRIAVDNGLIPVAHAGEEAPAEYVWEAINVLNARRIDHG 226
Query: 183 VCIHPKYGGTEETWIALCQSK-IPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCT 241
+ +E+ I L K IPV +C + + K K ++AG++V + +
Sbjct: 227 Y-----HAFEDESLIKLIAEKGIPVNMCPLTTLRIKYFNSILDVPVKRALDAGIAVTINS 281
Query: 242 DDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKIL 295
DD F + Y E L I + KL+ ++ + F + + ++ ++ +++
Sbjct: 282 DDPAYFGGYILDNYIAVYEGQGLRLIDMVKLAENSIRASFLKDSDKDRLLRELV 335
>UniRef50_Q4UZY3 Cluster: Adenosine deaminase; n=6; Xanthomonas|Rep:
Adenosine deaminase - Xanthomonas campestris pv.
campestris (strain 8004)
Length = 397
Score = 46.4 bits (105), Expect = 0.001
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 13/179 (7%)
Query: 89 QYIDSIIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNP-AVGNFGDFIPALN- 146
+Y+ ++R + A Q+ +A + V + NP AV ++ +
Sbjct: 126 RYVPYVLRVLPAPQVFGQMALAHALVAAGGSRAVAVNIVAPEDNPVAVADYARHMAMFRF 185
Query: 147 -RARQSGLKVTLHCGEVC----NPEE----VLEMLNFKPERIGHGVCIHPKYGGTEETWI 197
R G+ ++LH GE+ P + + + ++ RIGHGV + P +E
Sbjct: 186 FAQRYPGVPLSLHAGELTLGLVPPAQLRSHIRQAVDAGARRIGHGVDL-PYEDDAQELLQ 244
Query: 198 ALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYR 256
+ + ++ VE+ LTSN + + +H + AG+ VVL TDD GV ++ EY+
Sbjct: 245 RMRRDQVAVEINLTSN-DVILGVTGAAHPLAMYLRAGVPVVLSTDDAGVSRADMTHEYQ 302
>UniRef50_Q096I6 Cluster: Adenosine deaminase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Adenosine deaminase -
Stigmatella aurantiaca DW4/3-1
Length = 528
Score = 46.4 bits (105), Expect = 0.001
Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 6/106 (5%)
Query: 177 ERIGHGVCIHPKYGG--TEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAG 234
ERIGH V I + G E+ + ++ + VE+CLTSN + H +E
Sbjct: 360 ERIGHSVDIMRETAGDGAEDLLRDMHEAGVMVEICLTSN-RVLLGVSGTQHPLSNYLEQQ 418
Query: 235 LSVVLCTDDKGVFATSLSQEYRLCAESFAL---TRIQVAKLSLDAA 277
+ V L TDD+G+ S+++EY A L T +A++SL A
Sbjct: 419 VPVTLATDDQGILRGSITEEYVAAATDQRLDYKTLKYMARVSLQHA 464
>UniRef50_A5FE69 Cluster: Adenosine/AMP deaminase precursor; n=1;
Flavobacterium johnsoniae UW101|Rep: Adenosine/AMP
deaminase precursor - Flavobacterium johnsoniae UW101
Length = 471
Score = 46.4 bits (105), Expect = 0.001
Identities = 35/119 (29%), Positives = 58/119 (48%), Gaps = 11/119 (9%)
Query: 153 LKVTLHCGEVC----NPEEVLEMLNFK-----PERIGHGVCIHPKYGGTEETWIALCQSK 203
+K TLH GE+ PEE+ +N RIGHGV I + + + + Q
Sbjct: 307 VKYTLHAGELTLGLVQPEELTWHINDAIYVAGANRIGHGVDIAYE-ANSYDLLKYMAQKN 365
Query: 204 IPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESF 262
IP+E+ L SN + H F E + +V+ TDD G+ ++++++Y L A+ +
Sbjct: 366 IPIEINLVSN-EFILKVKENRHPFTLYKEFNVPIVISTDDAGILRSNMTEQYVLLAKRY 423
>UniRef50_Q553U5 Cluster: Adenosine deaminase-related growth factor;
n=2; Dictyostelium discoideum|Rep: Adenosine
deaminase-related growth factor - Dictyostelium
discoideum AX4
Length = 543
Score = 46.4 bits (105), Expect = 0.001
Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 14/175 (8%)
Query: 112 IAIERHKIHPDTVVGIEL-----SGNPAVGNFGDF--IPALNRARQSGLKVTLHCGEVC- 163
++++ +P T VG +L G P + F I L Q L H GE
Sbjct: 336 MSLDLRNKYPSTFVGYDLVGPEDEGYPLIYFIEQFAEIKKLGYQYQYPLDYYFHAGETIL 395
Query: 164 -NPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDY 222
N + + + +RIGHG+ + PK+ + + ++ I +E+C SN + D
Sbjct: 396 YNNTNLYDAILLNTKRIGHGIQL-PKHPLLMDL---VLKNDIGIEICPISNQILQYVSDM 451
Query: 223 ESHHFKELIEAGLSVVLCTDDKGVF-ATSLSQEYRLCAESFALTRIQVAKLSLDA 276
+H +L+ GL V + DD +F LS ++ S+ L Q+ +L++++
Sbjct: 452 RAHPGLDLLNRGLPVTISPDDPAIFNYGGLSYDFFELTYSWGLNLQQLKQLAINS 506
>UniRef50_Q9P6J8 Cluster: Adenine deaminase; n=1;
Schizosaccharomyces pombe|Rep: Adenine deaminase -
Schizosaccharomyces pombe (Fission yeast)
Length = 339
Score = 45.2 bits (102), Expect = 0.002
Identities = 42/161 (26%), Positives = 73/161 (45%), Gaps = 13/161 (8%)
Query: 124 VVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCG--EVCNPEEVLEML-NFKPERIG 180
++GI L N F+ RARQ G ++T HC + + + L + ERI
Sbjct: 163 IIGIGLDSNEENNPPIKFLKVFQRARQLGYRLTCHCDLHQKNTTTHIRQALEDIGVERID 222
Query: 181 HGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLC 240
HG+ I E +AL + IP VC S N + P + +++ GL V +
Sbjct: 223 HGINI---LDDPELIKLAL-ERNIPFTVCPFS--NEIVYPGKAQPEIRIMLDTGLKVTIN 276
Query: 241 TDDKG-VFATSLSQEYRLCAESFALTR---IQVAKLSLDAA 277
+DD + +++ + L + +LT+ +Q+ + S +AA
Sbjct: 277 SDDPAYMHCFYITENFNLAQKGASLTKKELVQICRNSFEAA 317
>UniRef50_Q9P6I7 Cluster: Adenosine deaminase; n=12; Ascomycota|Rep:
Adenosine deaminase - Schizosaccharomyces pombe (Fission
yeast)
Length = 367
Score = 45.2 bits (102), Expect = 0.002
Identities = 40/192 (20%), Positives = 77/192 (40%), Gaps = 5/192 (2%)
Query: 113 AIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEML 172
A++R+ V G+ L + F A + G++ T H GE +P + L
Sbjct: 164 ALKRNDFENGIVAGVGLDSSEVDFPPELFQEVYKLAAEKGIRRTGHAGEEGDPSYIRSGL 223
Query: 173 -NFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELI 231
N +RI HG+ + +E + + I + +C SN+ + +E +
Sbjct: 224 DNLSLQRIDHGI----RLVEDKELMKRVAEENIMLTMCPLSNLKLRCVNSIAELPVREFL 279
Query: 232 EAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELII 291
EAG+ + DD F + Y + F LT + ++ A + +E ++
Sbjct: 280 EAGVPFSINCDDPAYFGGYTLENYFAIQKHFNLTVKEWVFIANAAINGSWISGKRKEELL 339
Query: 292 GKILKFMNDYTS 303
+ K + +YT+
Sbjct: 340 SSVQKCVKEYTA 351
>UniRef50_A4REQ3 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 627
Score = 44.8 bits (101), Expect = 0.003
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 21/167 (12%)
Query: 104 QEVEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPALNRARQSGLKVTL----- 157
++VE + I+ K + + G +L G A GN F+P + R+ K L
Sbjct: 401 EQVENALEECIKFKKRWSNLIAGFDLVGEEAAGNPLKYFVPEFLKFREQCKKEELDIPFL 460
Query: 158 -HCGEVCN-----PE-EVLEMLNFKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEV 208
HCGE + P+ + + L +RIGHG + HP E+ + + I +E+
Sbjct: 461 FHCGETLDMGDDTPDGNLTDALLLNSKRIGHGFSLARHPYI--MEQ----MKKRNICLEL 514
Query: 209 CLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEY 255
C SN +TP + H L+ + L +D+ +F +SLS ++
Sbjct: 515 CPISNEVLGLTPRVKGHAMYNLLANNVHCTLNSDNGTLFKSSLSHDF 561
>UniRef50_UPI00015B4087 Cluster: PREDICTED: similar to CG5992-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG5992-PA - Nasonia vitripennis
Length = 521
Score = 44.4 bits (100), Expect = 0.004
Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 16/161 (9%)
Query: 104 QEVEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPALNRARQSGLKVTLHCGEV 162
QE+++ A + K PD VVG +L G G +F L RA + + H GE
Sbjct: 293 QELDQFLITARQLKKELPDFVVGFDLVGQEDKGYPLIEFADKL-RAISDDVHLFFHAGET 351
Query: 163 -----CNPEEVLEMLNFKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEVCLTSNVN 215
+ +++ + +RIGHG + HPK Q KI +E+ SN
Sbjct: 352 NWYGTSIDKNLIDAVMLNTKRIGHGYALVKHPKVLELAR------QKKIAIEIAPISNQV 405
Query: 216 TKITPDYESHHFKELIEAGLSVVLCTDDKGVF-ATSLSQEY 255
+ D +H L VV+ DD G++ A LS ++
Sbjct: 406 LDLVKDLRNHPASALFAQDYPVVISNDDPGLWGAQGLSYDF 446
>UniRef50_Q5FR10 Cluster: Adenosine deaminase; n=2;
Alphaproteobacteria|Rep: Adenosine deaminase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 389
Score = 44.4 bits (100), Expect = 0.004
Identities = 41/139 (29%), Positives = 62/139 (44%), Gaps = 11/139 (7%)
Query: 152 GLKVTLHCGEVCNPEEVLEMLNFK---------PERIGHGVCIHPKYGGTEETWIALCQS 202
G+K++LH GE+ E L RIGHGV + + + +
Sbjct: 190 GVKLSLHAGELTTGLVPTEGLRHHIRAAIDVAGANRIGHGVDVALE-DDPASLLAEMARR 248
Query: 203 KIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESF 262
+ VEV LTSN + + +H F AG+ V L TDD+GV L+QEY A+++
Sbjct: 249 HVMVEVNLTSN-DEILGIKGAAHPFPLYRRAGVPVALSTDDEGVSRGDLTQEYVRAAQTY 307
Query: 263 ALTRIQVAKLSLDAAQCIF 281
L+ + LS + F
Sbjct: 308 DLSYAALKTLSRTGLEYAF 326
>UniRef50_UPI0000DB7737 Cluster: PREDICTED: similar to Adenosine
deaminase-related growth factor A CG5992-PA, isoform A;
n=2; Apis mellifera|Rep: PREDICTED: similar to Adenosine
deaminase-related growth factor A CG5992-PA, isoform A -
Apis mellifera
Length = 496
Score = 44.0 bits (99), Expect = 0.005
Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 13/146 (8%)
Query: 118 KIHPDTVVGIELSGNPAVGNFGD-FIPALNRARQSGLKVTLHCGEV-----CNPEEVLEM 171
K++P+ V G +L G +G+ + F L Q + H GE E +++
Sbjct: 298 KMYPNFVAGFDLVGQEDLGHTLEYFADLLKDIGQYNISFFFHAGETNWLGTSTDENLVDA 357
Query: 172 LNFKPERIGHGVCIHPKYGGTEETWIALCQSK-IPVEVCLTSNVNTKITPDYESHHFKEL 230
+ RIGHG + + + L + I +E+ SN K+ D +H K L
Sbjct: 358 ILLNTRRIGHGYAL-----ASHPFLLELARKMDIAIEINPISNQVLKLVDDLRNHQAKIL 412
Query: 231 IEAGLSVVLCTDDKGVFAT-SLSQEY 255
G +V+ DD G++ + +LS ++
Sbjct: 413 FSKGYPLVISNDDPGLWGSRALSYDF 438
>UniRef50_Q1IM40 Cluster: Adenosine/AMP deaminase precursor; n=1;
Acidobacteria bacterium Ellin345|Rep: Adenosine/AMP
deaminase precursor - Acidobacteria bacterium (strain
Ellin345)
Length = 509
Score = 44.0 bits (99), Expect = 0.005
Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 5/104 (4%)
Query: 177 ERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLS 236
+RIGHGV + + + + + K+ VE+ LTSN + + + H ++ G+
Sbjct: 348 DRIGHGVDVMEEDNALDLVK-EMAKRKVMVEINLTSN-DVILGIRGKDHPLATYMKYGVP 405
Query: 237 VVLCTDDKGVFATSLSQEYRLCAESFALTRIQ---VAKLSLDAA 277
V L TDD+GV + LS EY A LT Q +A+ SL+ A
Sbjct: 406 VALSTDDEGVSRSDLSMEYMRGATDQGLTYAQLKTMARTSLEHA 449
>UniRef50_UPI00015B4088 Cluster: PREDICTED: similar to adenosine
deaminase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to adenosine deaminase - Nasonia vitripennis
Length = 512
Score = 43.2 bits (97), Expect = 0.009
Identities = 42/146 (28%), Positives = 61/146 (41%), Gaps = 16/146 (10%)
Query: 119 IHPDTVVGIELSGNPAVGN-FGDFIPALNRARQSGLKVTLHCGE-----VCNPEEVLEML 172
+ PD VVG +L G G DF L A H GE + E +++ +
Sbjct: 317 VQPDHVVGFDLVGQEDKGRPLKDFAKEL-LALGKETSFFFHAGETNWNGMQTDENLIDAV 375
Query: 173 NFKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKEL 230
+RIGHG + HPK + + KI +EV SN K+ D +H
Sbjct: 376 LLNTKRIGHGYALAKHPKLMQLVK------EKKIAIEVSPISNQVLKLVKDLRNHPASYF 429
Query: 231 IEAGLSVVLCTDDKGVF-ATSLSQEY 255
L VV+ DD G + A +LS ++
Sbjct: 430 FALDLPVVVSNDDPGFWGARALSYDF 455
>UniRef50_A4B200 Cluster: Adenosine deaminase; n=1; Alteromonas
macleodii 'Deep ecotype'|Rep: Adenosine deaminase -
Alteromonas macleodii 'Deep ecotype'
Length = 337
Score = 43.2 bits (97), Expect = 0.009
Identities = 37/138 (26%), Positives = 64/138 (46%), Gaps = 11/138 (7%)
Query: 120 HPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNP--EEVLEML-NFKP 176
H D ++G+ L + F ++AR GLK+T+HC N E + +++ + K
Sbjct: 156 HLDKLIGVGLDSDEKNNPPLKFAEVFSKARMWGLKLTMHCDVNQNNTLEHIRQVIEDIKV 215
Query: 177 ERIGHGVCIHPKYGGTEETWIALCQSK-IPVEVCLTSNVNTKITPDYESHHFKELIEAGL 235
+RI HGV I + L +SK + + VC S N + S K++++ GL
Sbjct: 216 DRIDHGVNIL-----ESDALCELAKSKGLGLTVCPVS--NKFVVQSLTSKELKKMLQQGL 268
Query: 236 SVVLCTDDKGVFATSLSQ 253
+ +DD F L++
Sbjct: 269 LPSINSDDPSYFRAYLNE 286
>UniRef50_UPI0000DAE38A Cluster: hypothetical protein
Rgryl_01000135; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000135 - Rickettsiella
grylli
Length = 519
Score = 42.7 bits (96), Expect = 0.011
Identities = 35/120 (29%), Positives = 59/120 (49%), Gaps = 13/120 (10%)
Query: 153 LKVTLHCGEVCNPEEVLEMLNFK---------PERIGHGVCIHPKYGGTEETWIALCQSK 203
+K++LH GE+ L L F RIGHGV I + E+ + + +
Sbjct: 300 VKISLHAGELVKGLVPLSGLRFHIREAIEIAHANRIGHGVSISYE-NNAEQLLQEMAKKQ 358
Query: 204 IPVEVCLTSNVNTKITPDYESHHFKELIEA-GLSVVLCTDDKGVFATSLSQEYRLCAESF 262
I VE+ L+SN I Y H L + + VL TDD+GV T+L++++++ +++
Sbjct: 359 IVVEINLSSNA--AILQVYGKQHPLLLYKHYQVPFVLSTDDEGVLRTNLTEQFKIAVKNY 416
>UniRef50_Q9VFS0 Cluster: CG9345-PA; n=1; Drosophila
melanogaster|Rep: CG9345-PA - Drosophila melanogaster
(Fruit fly)
Length = 506
Score = 42.7 bits (96), Expect = 0.011
Identities = 45/179 (25%), Positives = 73/179 (40%), Gaps = 16/179 (8%)
Query: 94 IIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPALNRARQSG 152
I+ +L +++I ++ + H+ P +VG +L G G +P L R
Sbjct: 284 IMAVYRGYELDHLKDIVEVFKKLHQALPHFLVGFDLVGQEDKGKPLYSLLPVL-RDLPPT 342
Query: 153 LKVTLHCGEV-----CNPEEVLEMLNFKPERIGHGVCI--HPKYGGTEETWIALCQSKIP 205
++ LH GE +L+ L RIGHG + HP A+ +I
Sbjct: 343 ARLFLHGGETNWFGASTDINLLDALLMNTTRIGHGYALAKHPILLN------AVKSRRIA 396
Query: 206 VEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVF-ATSLSQEYRLCAESFA 263
VE+ SN + D +H + + VV+C DD G + A LS ++ S A
Sbjct: 397 VELSPISNQVLHLVWDLRNHPGSQFFALDVPVVICNDDPGFWNAKGLSYDFYYAIMSLA 455
>UniRef50_Q179D4 Cluster: Adenosine deaminase; n=6; Culicidae|Rep:
Adenosine deaminase - Aedes aegypti (Yellowfever
mosquito)
Length = 524
Score = 42.7 bits (96), Expect = 0.011
Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 17/194 (8%)
Query: 105 EVEEIADIAIERHKIHPDTVVGIELSGNPAVG-NFGDFIPALNRARQSGLKVTLHCGE-- 161
E +I D A HK P + G +L G G + +F PAL + S + H GE
Sbjct: 310 EFLKIIDTAKRLHKKFPTFLAGFDLVGQEDPGRSLLEFAPALLKLPAS-INFFFHAGETN 368
Query: 162 ---VCNPEEVLEMLNFKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEVCLTSNVNT 216
+ + +++ + +RIGHG + HPK +E + + +I +E+ SN
Sbjct: 369 WYGMKTDQNLIDAVLLGSKRIGHGFAVLKHPKV--LKE----IKRRQICIEINPISNQVL 422
Query: 217 KITPDYESHHFKELIEAGLSVVLCTDDKGVF-ATSLSQEYRLCAESFALTRIQVAKLSLD 275
K+ D +H L VV+ +DD + +T LS ++ + A + + L
Sbjct: 423 KLVQDQRNHPAALLFSDNYPVVVSSDDPSFWRSTPLSHDFYVAFTGIASAKQDLRLLKQL 482
Query: 276 AAQCI-FSEANIRE 288
A I +S N E
Sbjct: 483 ALNSIEYSAMNSEE 496
>UniRef50_Q7QI64 Cluster: ENSANGP00000003634; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000003634 - Anopheles gambiae
str. PEST
Length = 522
Score = 42.3 bits (95), Expect = 0.015
Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 17/162 (10%)
Query: 105 EVEEIADIAIERHKIHPDTVVGIELSGNPAVG-NFGDFIPALNRARQSG--LKVTLHCGE 161
E+E+ + P VVG +L G + + F L + S K H GE
Sbjct: 306 ELEKALQLYDSLSTTFPGFVVGFDLVGQEDINRSLKSFSSLLVQPPVSSGPPKYFFHAGE 365
Query: 162 VCN-----PEEVLEMLNFKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEVCLTSNV 214
+ E V++ + +RIGHG + HP W A+ +I +EVC SN
Sbjct: 366 IAGYFTEADENVIDAVLLDTKRIGHGYALMKHPIL------WHAVQHKQIAIEVCPISNQ 419
Query: 215 NTKITPDYESHHFKELIEAGLSVVLCTDDKGVF-ATSLSQEY 255
+ D +H + + +V+ +DD G + A +S +Y
Sbjct: 420 VLGLVRDLRNHPASFYVAQNIPIVITSDDPGFWDAVGVSFDY 461
>UniRef50_A0CG01 Cluster: Chromosome undetermined scaffold_178,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_178,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 730
Score = 42.3 bits (95), Expect = 0.015
Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 3/90 (3%)
Query: 206 VEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATS---LSQEYRLCAESF 262
+ + ++ N K+ Y F GL+V L TDD + + L +EY + + F
Sbjct: 597 IGISMSPIANNKLICKYADSPFNSYFRQGLNVCLSTDDPLMLHMTDQPLLEEYAIAQQIF 656
Query: 263 ALTRIQVAKLSLDAAQCIFSEANIRELIIG 292
L+ + +A+L+ ++ +C E+ I+E +G
Sbjct: 657 DLSNVDMAELARNSVRCSSFESIIKEFYVG 686
>UniRef50_Q4IMJ1 Cluster: Adenosine deaminase; n=1; Gibberella
zeae|Rep: Adenosine deaminase - Gibberella zeae
(Fusarium graminearum)
Length = 353
Score = 42.3 bits (95), Expect = 0.015
Identities = 36/176 (20%), Positives = 69/176 (39%), Gaps = 5/176 (2%)
Query: 91 IDSIIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQ 150
++ I+ + + E + D ++R + T+ G + + F R +
Sbjct: 141 VELIVCILRHLPVPESHALVDTLLDRGHFNDGTLTGFGMVSSEKAFPPELFTDVYARVAK 200
Query: 151 SGLKVTLHCGEVCNPEEVLEML-NFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVC 209
+G +T H GE P + L + K RI HG+ E L ++ + C
Sbjct: 201 TGTHLTTHAGEEAPPSFITASLEHLKVSRIDHGLAA----AQDPELLKKLAANRTLLTFC 256
Query: 210 LTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALT 265
SNV P+ +E ++AG+ + +DD F + + Y ++F L+
Sbjct: 257 PWSNVALCNLPELADAPVREFLDAGVLFSVNSDDPAYFGAYVQEVYCRVQDTFNLS 312
>UniRef50_Q6ALG5 Cluster: Related to adenosine deaminase; n=2;
Bacteria|Rep: Related to adenosine deaminase -
Desulfotalea psychrophila
Length = 491
Score = 41.9 bits (94), Expect = 0.020
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
Query: 177 ERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLS 236
+RIGHGV + Y + + K VE+ TSN + + H + G+
Sbjct: 353 QRIGHGVDL--PYEEDAIDLLRAIKEKAVVEINFTSN-EFILGVKGQEHPYLIYSAYGVP 409
Query: 237 VVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELII 291
+V+CTDD GV +LS EY L A + + + + + ++ + F RE I
Sbjct: 410 IVICTDDSGVSRNNLSHEYVLLATRYKPSYQTIKQYAFNSIKYSFLPNKEREKTI 464
>UniRef50_P15274 Cluster: AMP deaminase; n=13;
Saccharomycetales|Rep: AMP deaminase - Saccharomyces
cerevisiae (Baker's yeast)
Length = 810
Score = 41.9 bits (94), Expect = 0.020
Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 158 HCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTK 217
HCGE +PE ++ I HG+ + + ++ V + ++ N
Sbjct: 630 HCGEAGDPEHLVSAY-LLAHGISHGILLR------KVPFVQYLYYLDQVGIAMSPLSNNA 682
Query: 218 ITPDYESHHFKELIEAGLSVVLCTDDKGVFATS---LSQEYRLCAESFALTRIQVAKLSL 274
+ Y+ + F + GL+V L TDD F+ + L +EY + A+ + L+ + + +L+
Sbjct: 683 LFLTYDKNPFPRYFKRGLNVSLSTDDPLQFSYTREPLIEEYSVAAQIYKLSNVDMCELAR 742
Query: 275 DAAQCIFSEANIRELIIGK 293
++ EA I++ IGK
Sbjct: 743 NSVLQSGWEAQIKKHWIGK 761
>UniRef50_Q291C7 Cluster: GA10106-PA; n=2; Diptera|Rep: GA10106-PA -
Drosophila pseudoobscura (Fruit fly)
Length = 552
Score = 41.1 bits (92), Expect = 0.034
Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 20/182 (10%)
Query: 83 QYITKKQYIDSIIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDF 141
QY+ KQ + +R E +++ + + I++ K P V+G +L G VG+ F
Sbjct: 315 QYV--KQCTELNVRDSERARI--LCSVLRISLPLQKEFPGFVIGFDLVGQEDVGHPLSQF 370
Query: 142 IPALNRARQSGLKVTLHCGEVC-----NPEEVLEMLNFKPERIGHGVCI--HPKYGGTEE 194
+ L + + + H G+ E +++ + +RIGHG I HP +
Sbjct: 371 VEELIKLPDN-INFYFHAGQTNWYGSHVDENLIDAIMLGTKRIGHGYTITKHPLLMQLAK 429
Query: 195 TWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVF-ATSLSQ 253
I +EVC SN ++ DY +H LI + +V+C+ + A+ LS
Sbjct: 430 ------YMNIALEVCPVSNQVLQLGSDYRNHPAATLIAENVPLVICSGSPAFWCASPLSH 483
Query: 254 EY 255
++
Sbjct: 484 DF 485
>UniRef50_A6SNR0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 558
Score = 41.1 bits (92), Expect = 0.034
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 22/179 (12%)
Query: 101 SQLQEVEEIADIAIERHKI-HPDTVVGIELSGNPAVGN-FGDFIPALN------RARQSG 152
++L E + +A R K +PD + G +L G +G D +P + R+
Sbjct: 215 NRLMETKSQHMVACMRVKERYPDLISGYDLEGQEELGRTLEDLMPICLWFKEQCKNRKLN 274
Query: 153 LKVTLHCGEVC-----NPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSK-IPV 206
+ LH GE N + + + RIGHG + PK+ EE +C+ + I +
Sbjct: 275 IPFFLHAGECLGNGDVNDHNLYDAILLGTRRIGHGYSL-PKHPLLEE----ICKERQIMI 329
Query: 207 EVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDD---KGVFATSLSQEYRLCAESF 262
E C S+ + ++T +H L+ G++ L DD G +S E+ +C S+
Sbjct: 330 ESCPLSDESLRLTHSTSAHTLPMLLAKGVNASLNCDDPFLSGQEMVGVSLEFFMCLWSW 388
>UniRef50_Q8YNZ1 Cluster: All4418 protein; n=14; Cyanobacteria|Rep:
All4418 protein - Anabaena sp. (strain PCC 7120)
Length = 347
Score = 40.7 bits (91), Expect = 0.045
Identities = 58/247 (23%), Positives = 96/247 (38%), Gaps = 30/247 (12%)
Query: 34 LSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTP--RDTQYITKKQYI 91
L E ++ ++ S+ + L + + Y+ELR TP R +++++ Q I
Sbjct: 52 LDEYLELHTLVESVQTVETLPYFIYRLVRGAYIFENLAYLELRYTPYLRTPEHLSQSQRI 111
Query: 92 DS---IIRAM-EASQLQEVEEIADIAIERHKIHP---------------DTVVGIELSGN 132
D I++ + EAS E I + H P + V GI+++G
Sbjct: 112 DKMAEIVKVVGEASSQPEYPIITSQILCMHTRLPYEVNKAIIDLAAQNKNYVCGIDVAGG 171
Query: 133 PA--VGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYG 190
+ ++I R G+ T H E P L RIGHG+ I Y
Sbjct: 172 DSHYADRLPEWISLYEYGRSLGINTTGHFYET--PSGCYPQLLPYLMRIGHGIQIPLLY- 228
Query: 191 GTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHH--FKELIEAGLSVVLCTDDKGVFA 248
E + + +EVC T+ + T D F +AG+ + +CTD+ G+
Sbjct: 229 --PELLPDVARRGQCLEVCPTTYIQTGTLQDIRQLKLVFDRCFDAGVDIAICTDNAGLHN 286
Query: 249 TSLSQEY 255
L EY
Sbjct: 287 VRLPFEY 293
>UniRef50_Q22E33 Cluster: Adenosine/AMP deaminase family protein;
n=1; Tetrahymena thermophila SB210|Rep: Adenosine/AMP
deaminase family protein - Tetrahymena thermophila SB210
Length = 475
Score = 40.7 bits (91), Expect = 0.045
Identities = 36/164 (21%), Positives = 69/164 (42%), Gaps = 14/164 (8%)
Query: 94 IIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIEL-SGNPAVGNFGDFIPALNRARQSG 152
+I+ ++ + ++E+ A+ K HP+ + +L A + PAL + ++
Sbjct: 250 VIQGLKMWDVNQIEQYMRDALIAKKHHPELICAFDLVQEEDAFKTMLEMAPALIKMKEMQ 309
Query: 153 LKV------TLHCGEVCNP---EEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSK 203
++ H GE + + ++L +RIGHG+ + E+ + +
Sbjct: 310 AEIGVELPFVFHGGESLHTLKNTNLFDVLLLGTKRIGHGINLSQHSYLLEK----IKNDE 365
Query: 204 IPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVF 247
I +E+C SN K D H K + G+ V + DD G F
Sbjct: 366 ICLEICPVSNQILKYIDDIRLHPIKTFLNYGVKVSINPDDPGFF 409
>UniRef50_Q9U7C6 Cluster: Salivary gland growth factor-1 precursor;
n=1; Glossina morsitans morsitans|Rep: Salivary gland
growth factor-1 precursor - Glossina morsitans morsitans
(Savannah tsetse fly)
Length = 494
Score = 40.3 bits (90), Expect = 0.060
Identities = 37/148 (25%), Positives = 58/148 (39%), Gaps = 13/148 (8%)
Query: 105 EVEEIADIAIERHKIHPDTVVGIELSGNPAVG-NFGDFIPALNRARQSGLKVTLHCGEV- 162
E+ + D+ P+T++G++ G G F A + G K+ LH GE
Sbjct: 284 EIRKNFDLYKNLRSKFPNTIIGLDFVGWEDKGLALQPFADDFTSATRDGSKLFLHAGETN 343
Query: 163 ---CNPEEVLEMLNFKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEVCLTSNVNTK 217
+ +++ L RIGHG + HP + + I VE+C SN
Sbjct: 344 QLGSTDQNLVDALLLNTTRIGHGYALAKHPYLMRDVK------EKDIAVELCPVSNQVNS 397
Query: 218 ITPDYESHHFKELIEAGLSVVLCTDDKG 245
D +H L+ + VVL D G
Sbjct: 398 FVEDLRNHPGAILMSENVPVVLGNDSPG 425
>UniRef50_Q2GSL1 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 688
Score = 40.3 bits (90), Expect = 0.060
Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 144 ALNRARQSGLKVTLHCGEVCN-----PEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIA 198
AL +A + + LHCGE + +L+ L +RIGHG + P++
Sbjct: 493 ALCKAAEVEIPFLLHCGETLDIGTDTDGNLLDALLLGAKRIGHGFAL-PRH---PYVMSR 548
Query: 199 LCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEY 255
+ Q + VEVC SN +TP H L+ + + D+ +F + LS ++
Sbjct: 549 MKQRGVCVEVCPISNEILGLTPRMSGHAVYSLLANNVPCTISADNGTLFRSRLSHDF 605
>UniRef50_A6S7C8 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 598
Score = 40.3 bits (90), Expect = 0.060
Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 18/162 (11%)
Query: 104 QEVEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPAL----NRARQSGLKVTL- 157
+++ E D + +P+ + G +L G G D +P L + Q G+++
Sbjct: 342 RKIVEDMDACLTIKMTYPNLISGYDLVGQEDAGRPLKDLLPELFWFKKQCAQEGVEIPFF 401
Query: 158 -HCGEVCNP-----EEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALC-QSKIPVEVCL 210
H GE + + + + RIGHG ++ I L + KI VE C
Sbjct: 402 FHAGECLGDGSDTDQNLFDAVLLGTRRIGHGFSLYK-----HPLLIDLVKEKKILVESCP 456
Query: 211 TSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLS 252
SN ++ SH L+ G+S LC DD + ++
Sbjct: 457 ISNEVLRLCASIMSHPLPALLARGVSCSLCNDDPSILGQDVN 498
>UniRef50_A4ZQ11 Cluster: Adenyl deaminase; n=1; Dekkera
bruxellensis|Rep: Adenyl deaminase - Dekkera
bruxellensis (Brettanomyces custersii)
Length = 350
Score = 40.3 bits (90), Expect = 0.060
Identities = 34/165 (20%), Positives = 71/165 (43%), Gaps = 7/165 (4%)
Query: 141 FIPALNRARQSGLKVTLHCGEVCNPEEVLEML--NFKPERIGHGVCIHPKYGGTEETWIA 198
F A +A++ G K+T H GE +P + ++ + +R+ HG + E+
Sbjct: 188 FHDAYVKAKRHGYKLTAHAGEYESPWQNVDYVVNTLHVDRVDHGYSMLHNPKLVEQ---L 244
Query: 199 LCQSKIPVEVCLTSNVNTKITPD--YESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYR 256
+ + K+ V S TP+ + H +++I+ GL + TDD + + ++++
Sbjct: 245 VSEKKVITVVPTNSYYLRNFTPEEWTQKHPIRKMIKLGLRIHPNTDDPTLHDSDSTKDWM 304
Query: 257 LCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKILKFMNDY 301
+ F T + SL+ ++ +E + I +F Y
Sbjct: 305 MMVSCFGATISDLETFSLNGVDGCWAPEEKKEELRAAITQFFEKY 349
>UniRef50_A1D5P4 Cluster: Adenosine deaminase family protein; n=5;
Trichocomaceae|Rep: Adenosine deaminase family protein -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 587
Score = 40.3 bits (90), Expect = 0.060
Identities = 36/161 (22%), Positives = 66/161 (40%), Gaps = 16/161 (9%)
Query: 104 QEVEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPALN--RARQSGLKVTL--- 157
+++ + IA+ER + P+ G +L +G D P L R + L +T+
Sbjct: 339 EKITKSMKIALERKQRFPELFSGYDLVAQEDLGRPLSDLAPELIWFREQTEYLNLTIPFF 398
Query: 158 -HCGEVCNPEE-----VLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLT 211
H GE +++ + F RIGHG ++ +E + + + VEVC
Sbjct: 399 FHAGETLGDGNSTDYNLVDAILFNSRRIGHGFSLYKHPTLIDE----VIEKAVMVEVCPI 454
Query: 212 SNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLS 252
SN ++ D H +I G+ + DD + ++
Sbjct: 455 SNEVLRLATDILHHPLPAMIAHGVPTAISNDDPAILGQDIA 495
>UniRef50_Q9VFS1 Cluster: CG9621-PA; n=2; Sophophora|Rep: CG9621-PA
- Drosophila melanogaster (Fruit fly)
Length = 502
Score = 39.9 bits (89), Expect = 0.079
Identities = 41/166 (24%), Positives = 67/166 (40%), Gaps = 15/166 (9%)
Query: 96 RAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPALNRARQSGLK 154
RA E L+ + + H P+ V+G +L G G +I L+ S
Sbjct: 288 RASEEEMLRRITTFKQL----HHAKPNFVIGFDLIGQEDTGEPLNRYINQLSDL-PSTAN 342
Query: 155 VTLHCGEVC----NPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCL 210
H GE +++ + +RIGH + PK+ + W + + I +EV
Sbjct: 343 YFFHAGETNWNGRTDWNMMDAILLNTKRIGHAFAL-PKH---PQLWSTIKKRNIAIEVNP 398
Query: 211 TSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVF-ATSLSQEY 255
SN D +H LI +V+ +DD GV+ A LS ++
Sbjct: 399 ISNQVLGFVWDLRNHPASFLIAENFPIVISSDDPGVWGAKGLSYDF 444
>UniRef50_A0E0U4 Cluster: Chromosome undetermined scaffold_72, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_72,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 695
Score = 39.5 bits (88), Expect = 0.10
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 13/151 (8%)
Query: 149 RQSGL---KVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIP 205
+Q GL K HCGE N + L + I HG+ + E L Q
Sbjct: 505 KQRGLNTFKFRPHCGEAGNIDH-LATAYLVSDGINHGLELQKS--PVLEYLFYLKQ---- 557
Query: 206 VEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATS---LSQEYRLCAESF 262
+ + ++ N K+ Y+ F++ + GL+V L TDD + + L +EY + ++ F
Sbjct: 558 IGIAMSPVSNNKLFCRYQKSPFQKYFQIGLNVCLSTDDPLILHLTNEPLLEEYAIASQIF 617
Query: 263 ALTRIQVAKLSLDAAQCIFSEANIRELIIGK 293
L+ I A+L+ ++ + E I++ IG+
Sbjct: 618 DLSAIDQAELARNSVRQSSFEKEIKDFWIGE 648
>UniRef50_Q0UD18 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 437
Score = 39.5 bits (88), Expect = 0.10
Identities = 22/79 (27%), Positives = 39/79 (49%)
Query: 177 ERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLS 236
+RIGHG + E+ I +E+C SN + + + H F EL+ AG+
Sbjct: 305 KRIGHGFALMKHPHLVEKFKKTKNSPGICIELCPISNELLHLCRNIKEHPFPELLAAGIP 364
Query: 237 VVLCTDDKGVFATSLSQEY 255
+ +D+ +F+ S+S E+
Sbjct: 365 CTVNSDNPSLFSNSMSHEF 383
>UniRef50_A5K7U3 Cluster: Adenosine/AMP deaminase, putative; n=6;
Plasmodium|Rep: Adenosine/AMP deaminase, putative -
Plasmodium vivax
Length = 697
Score = 39.1 bits (87), Expect = 0.14
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 10/119 (8%)
Query: 158 HCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTK 217
HCGE+ N + M +RI HG+ + + L K + + ++ N
Sbjct: 519 HCGEIGNISHLATMF-LLADRINHGINLRKS-----PVLLYLYYLK-QIGLAVSPLSNNA 571
Query: 218 ITPDYESHHFKELIEAGLSVVLCTDDKGVFATS---LSQEYRLCAESFALTRIQVAKLS 273
+ E + FK + GL+V L TDD +F + L +EY +CA + L+ + + +++
Sbjct: 572 LFLQIEKNPFKRFFKIGLNVSLSTDDPLMFHFTDEPLLEEYSVCAHIWKLSTVDLCEIA 630
>UniRef50_Q95WT8 Cluster: Salivary adenosine deaminase; n=2;
Culicini|Rep: Salivary adenosine deaminase - Culex
quinquefasciatus (Southern house mosquito)
Length = 502
Score = 38.7 bits (86), Expect = 0.18
Identities = 36/148 (24%), Positives = 60/148 (40%), Gaps = 11/148 (7%)
Query: 104 QEVEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPALNRARQSGLKVTLHCGEV 162
+ VE + I ++ PD VVG +L G + N F L + ++ H GE
Sbjct: 288 ETVESFLEKFIALNQEFPDLVVGFDLVGQEDINNPLILFTDQLCKFEKTA-PYFFHAGET 346
Query: 163 --CNPEEVLEMLN---FKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTK 217
E L +++ RIGHG ++ W + Q I +E+C SN +
Sbjct: 347 NGYGSEADLNLVDAVLLNSRRIGHGYSLYKH----PVLWKMVKQKGIALEICPLSNQVLR 402
Query: 218 ITPDYESHHFKELIEAGLSVVLCTDDKG 245
+ D +H + + +V+ DD G
Sbjct: 403 LVTDLRNHPAVFYVSESVPIVIAPDDPG 430
>UniRef50_Q7KGG1 Cluster: Adenosine deaminase-related growth factor
E; n=2; Drosophila melanogaster|Rep: Adenosine
deaminase-related growth factor E - Drosophila
melanogaster (Fruit fly)
Length = 539
Score = 38.3 bits (85), Expect = 0.24
Identities = 51/190 (26%), Positives = 79/190 (41%), Gaps = 21/190 (11%)
Query: 80 RDTQYITKKQ---YIDS--IIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPA 134
+DT KK+ +IDS I + Q + V E E +K P VVG +L G
Sbjct: 291 KDTLERFKKEHPGFIDSKLIYAPIRHVQPELVGEYIKECTELNKEFPSFVVGFDLVGQED 350
Query: 135 VGN-FGDFIPALNRARQSGLKVTLHCGEVC-----NPEEVLEMLNFKPERIGHGVCI--H 186
VG+ +F L + + H G+ + +L+ + +RIGHG I H
Sbjct: 351 VGHPLSNFAAELLKLPDH-IHFYFHAGQTNWYGSHVDQNLLDAIVLGTKRIGHGYTITKH 409
Query: 187 PKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGV 246
P + I +EVC SN ++ DY SH LI + +V+ + G
Sbjct: 410 PVLMRLAK------YLNIALEVCPVSNQVLQLGSDYRSHPAATLIAENVPMVIASGSPGF 463
Query: 247 F-ATSLSQEY 255
+ A LS ++
Sbjct: 464 WRAAPLSHDF 473
>UniRef50_Q7SGM7 Cluster: Putative uncharacterized protein NCU08056.1;
n=1; Neurospora crassa|Rep: Putative uncharacterized
protein NCU08056.1 - Neurospora crassa
Length = 1612
Score = 38.3 bits (85), Expect = 0.24
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Query: 80 RDTQYITKKQYIDSIIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFG 139
RDT K Y+DSII +E ++Q+ IA + +E+ K +G+EL+ P++ F
Sbjct: 1031 RDTPRAEKLAYVDSIINLLELEEIQDA-IIASLGVEQKK---RLTIGVELAAKPSLLLFL 1086
Query: 140 DFIPALNRARQSGLKVTLHCGEVC 163
D P QS + + ++C
Sbjct: 1087 D-EPTSGLDSQSAMSIVRFLRKLC 1109
>UniRef50_Q8PYN8 Cluster: Conserved protein; n=4;
Methanosarcinaceae|Rep: Conserved protein -
Methanosarcina mazei (Methanosarcina frisia)
Length = 369
Score = 38.3 bits (85), Expect = 0.24
Identities = 40/148 (27%), Positives = 69/148 (46%), Gaps = 14/148 (9%)
Query: 126 GIELSG-NPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVC 184
G+ +SG N N I A R R+ +H GE N ++ + L+ +P+ +
Sbjct: 175 GLGMSGANDLDMNLLQEITACTRERKK--LFAIHAGEK-NRSDIEKALSLEPDLL----- 226
Query: 185 IHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDK 244
IH + G ++ + Q+KIPV VC SN T E++EAG+ V TD+
Sbjct: 227 IHLTHAGKKDL-DEIAQAKIPVVVCPRSNFVTGAG----MAPIAEMLEAGIRVAAGTDNV 281
Query: 245 GVFATSLSQEYRLCAESFALTRIQVAKL 272
+ + ++ E ++ F++ QV K+
Sbjct: 282 MLNSVNMFAEMEFMSKIFSIDDRQVFKI 309
>UniRef50_Q4S691 Cluster: Chromosome 9 SCAF14729, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 9 SCAF14729, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 373
Score = 37.9 bits (84), Expect = 0.32
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 3/68 (4%)
Query: 118 KIHPDTVVGIELSGNPAVGNFG--DFIPALNRARQSGLKVTLHCGEVCNPEEVLEMLN-F 174
K + VV I+L+G+ ++ + D A A + G+ T+H GEV P V E +
Sbjct: 161 KYRHEGVVAIDLAGDESLSSETNPDHRRAYEEAARCGIHRTVHAGEVGPPSVVKEAVEVL 220
Query: 175 KPERIGHG 182
K ER+GHG
Sbjct: 221 KAERVGHG 228
>UniRef50_Q38ZJ2 Cluster: Adenosine deaminase; n=3; Bacteria|Rep:
Adenosine deaminase - Lactobacillus sakei subsp. sakei
(strain 23K)
Length = 339
Score = 37.9 bits (84), Expect = 0.32
Identities = 43/197 (21%), Positives = 82/197 (41%), Gaps = 9/197 (4%)
Query: 108 EIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCG--EVCNP 165
E A +E K + ++GI L + F+ A G ++T+H +V +
Sbjct: 148 ESARQLLEIAKPYQAKILGIGLDSDEHHNPPLKFLREYGDAVAQGYRITMHADIDQVDSI 207
Query: 166 EEVLEMLNF-KPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYES 224
+ + + L + ER+ HG I + W+ Q KI + C SN + D +
Sbjct: 208 QHIQQALEIIRVERLDHGTNIVENPDLVD--WVE--QLKIGLTFCPLSN--RLVADDMKD 261
Query: 225 HHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIFSEA 284
ELI+ + V + +DD F ++ Y LT QV +L+ ++ + +
Sbjct: 262 REVLELIDHNVKVSINSDDPAYFGGYINDNYEANTTKNDLTIDQVVQLAKNSFETAWISD 321
Query: 285 NIRELIIGKILKFMNDY 301
++ + +I ++ DY
Sbjct: 322 FQKQTYLAEIDAYVADY 338
>UniRef50_A6R6E4 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized
protein - Ajellomyces capsulatus NAm1
Length = 1116
Score = 37.9 bits (84), Expect = 0.32
Identities = 42/174 (24%), Positives = 71/174 (40%), Gaps = 19/174 (10%)
Query: 121 PDTVVGIELSGNPAVGN-FGDFIPAL----NRARQSGLKVTL--HCGE-VCNPEE----V 168
P V G ++ G G D +P L + ++G+ + H GE V + +E +
Sbjct: 885 PGLVAGYDIVGQEEKGRTLADLVPVLFWFKKKCVEAGVDIPFFFHAGEWVGDGDETDHNL 944
Query: 169 LEMLNFKPERIGHGVCIHPKYGGTEETWIALC-QSKIPVEVCLTSNVNTKITPDYESHHF 227
+ + RIGH + +H I L + KI +E C SN ++T +H
Sbjct: 945 FDAILLGARRIGHALTLHK-----HPLLIDLVKEKKILIECCPISNEVLRLTSSIMTHPL 999
Query: 228 KELIEAGLSVVLCTDDKGVFATSLSQ-EYRLCAESFALTRIQVAKLSLDAAQCI 280
L+ + V LC DD + S+ + C L + +A L++ A I
Sbjct: 1000 PALLARAVPVALCNDDPTLLGYGKSRFTHDFCQVLNGLENVGLAGLAMMAENSI 1053
>UniRef50_A6L6P5 Cluster: Putative uncharacterized protein; n=1;
Bacteroides vulgatus ATCC 8482|Rep: Putative
uncharacterized protein - Bacteroides vulgatus (strain
ATCC 8482 / DSM 1447 / NCTC 11154)
Length = 882
Score = 37.5 bits (83), Expect = 0.42
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 13/107 (12%)
Query: 203 KIPVEVCLTSNVNTKITPDYESHHFKELIEAGLS---------VVLCTDDKGVFATSLSQ 253
+I +E TSN +Y+ H + +GL+ V + TDD+GVF+TSL +
Sbjct: 773 RISIECNPTSNYKIGEMSNYDEHPILKFYNSGLNTPYNKHDIAVSINTDDQGVFSTSLER 832
Query: 254 EYRLCAESFALTRIQVAKLSLDAAQCIFSEANIRELIIGKILKFMND 300
EY L A A+ R Q Q I IR++ + + +F ND
Sbjct: 833 EYSLIA--LAIERHQTEGFKNSPRQIIDWLDKIRQMSVEQ--QFDND 875
>UniRef50_P50998 Cluster: AMP deaminase; n=1; Schizosaccharomyces
pombe|Rep: AMP deaminase - Schizosaccharomyces pombe
(Fission yeast)
Length = 846
Score = 37.5 bits (83), Expect = 0.42
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 10/138 (7%)
Query: 158 HCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTK 217
HCGE + + + I HG+ + K + W +IP+ + SN
Sbjct: 602 HCGEAGDTDHLASAFLLS-HGINHGILLR-KVPFLQYLWYL---DQIPIAMSPLSN--NA 654
Query: 218 ITPDYESHHFKELIEAGLSVVLCTDDKGVFATS---LSQEYRLCAESFALTRIQVAKLSL 274
+ Y+ + F + GL+V L TDD FA + L +EY + A+ + L+ + + +L+
Sbjct: 655 LFLAYDKNPFLTYFKRGLNVSLSTDDPLQFAFTREPLIEEYAVAAQIYKLSAVDMCELAR 714
Query: 275 DAAQCIFSEANIRELIIG 292
++ E ++E +G
Sbjct: 715 NSVLQSGFERQLKERWLG 732
>UniRef50_A3U074 Cluster: Adenosine deaminase; n=1; Oceanicola
batsensis HTCC2597|Rep: Adenosine deaminase - Oceanicola
batsensis HTCC2597
Length = 85
Score = 37.1 bits (82), Expect = 0.56
Identities = 17/58 (29%), Positives = 31/58 (53%)
Query: 224 SHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLSLDAAQCIF 281
+H+ L+ AGL V + +DD F +++ YR CA + LT ++ L+ ++ F
Sbjct: 2 AHNLARLLRAGLHVTVNSDDPPYFGGYVNENYRQCAAALDLTAAELITLARNSITAAF 59
>UniRef50_Q8NIZ8 Cluster: Related to cecr1 protein; n=6;
Pezizomycotina|Rep: Related to cecr1 protein -
Neurospora crassa
Length = 591
Score = 37.1 bits (82), Expect = 0.56
Identities = 32/144 (22%), Positives = 57/144 (39%), Gaps = 16/144 (11%)
Query: 121 PDTVVGIELSGNPAVG-NFGDFIPAL----NRARQSGLKVT--LHCGEVCNPEEVLE--- 170
P + G +L G G + D +P L + G+++ LH GE + ++
Sbjct: 365 PHLIAGYDLVGPEDAGRHLTDLLPELFWFRKQCAAEGVEIPFFLHAGETLGDGDAVDHNL 424
Query: 171 --MLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFK 228
L RIGHG ++ + A+ ++ +E C SN ++T H
Sbjct: 425 FDALLLGARRIGHGFSLYKH----PQLIKAVKDKRVLIESCPISNEVLRLTGSIMQHPLP 480
Query: 229 ELIEAGLSVVLCTDDKGVFATSLS 252
L+ G+ LC DD + ++
Sbjct: 481 ALLARGVPCALCNDDPAILGQDMA 504
>UniRef50_Q5UWY8 Cluster: Chlorohydrolase family protein; n=1;
Haloarcula marismortui|Rep: Chlorohydrolase family
protein - Haloarcula marismortui (Halobacterium
marismortui)
Length = 249
Score = 37.1 bits (82), Expect = 0.56
Identities = 43/170 (25%), Positives = 79/170 (46%), Gaps = 16/170 (9%)
Query: 107 EEIADIAIERHKIHPDTVVGIELS-GNPAVG-NFGDFIPALNRARQSGLKVTLHCGEVCN 164
+ ++D +E + +T +EL G A G N +F RQ+G +H GEV +
Sbjct: 32 DALSDSPLESVVLGRETTDAMELGDGFGASGANDSEFGAERRATRQAGKLFGIHAGEV-D 90
Query: 165 PEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKI-TPDYE 223
++ L+ P+ + H +H K E + S+IPV VC SN+ T + P E
Sbjct: 91 SSDINPALDLDPDFLVH--MVHAKSLHLER----VADSEIPVVVCPRSNIVTGVGRPPVE 144
Query: 224 SHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESFALTRIQVAKLS 273
+ + +V L TD+ + + S+ +E A+ + L+ +V +++
Sbjct: 145 A------LADRTTVALGTDNVMLNSPSMFREMEFTAKLYDLSAREVLRMA 188
>UniRef50_Q8EZ87 Cluster: Adenosine deaminase; n=4; Leptospira|Rep:
Adenosine deaminase - Leptospira interrogans
Length = 441
Score = 36.7 bits (81), Expect = 0.74
Identities = 17/60 (28%), Positives = 30/60 (50%)
Query: 201 QSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAE 260
Q+ +E C +SN + + ESH + + + TDD G+F TS+ +E+ A+
Sbjct: 344 QTNAIIESCPSSNEYIGMVVNPESHPILRFAKNDMKFTISTDDPGIFGTSIKEEFSKAAK 403
>UniRef50_Q80SY6-3 Cluster: Isoform 3 of Q80SY6 ; n=2;
Eutheria|Rep: Isoform 3 of Q80SY6 - Mus musculus
(Mouse)
Length = 114
Score = 36.3 bits (80), Expect = 0.98
Identities = 14/31 (45%), Positives = 21/31 (67%)
Query: 26 IGAGDTRNLSECFQVFSIAHSLTSTSEALVM 56
I G R L ECFQ+F + H LT+++E ++M
Sbjct: 54 IDKGKKRTLQECFQMFQVIHQLTTSAEDILM 84
>UniRef50_A7IPF6 Cluster: Adenosine/AMP deaminase precursor; n=1;
Xanthobacter autotrophicus Py2|Rep: Adenosine/AMP
deaminase precursor - Xanthobacter sp. (strain Py2)
Length = 519
Score = 35.9 bits (79), Expect = 1.3
Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Query: 178 RIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSV 237
RIGHG + + E + + + +E+ LTS+ + + +H + AG+ V
Sbjct: 368 RIGHGTAVGFERN-MEGLLAEMRRRGVTIEIALTSS-DVILGVRGRAHPIVTYLNAGVPV 425
Query: 238 VLCTDDKGVFATSLSQEYRLCAESFAL 264
L TDD GV L+ EY A L
Sbjct: 426 TLATDDAGVSRIDLTNEYFRAARDHGL 452
>UniRef50_Q0SBH5 Cluster: Arylsulfatase; n=1; Rhodococcus sp.
RHA1|Rep: Arylsulfatase - Rhodococcus sp. (strain RHA1)
Length = 790
Score = 35.5 bits (78), Expect = 1.7
Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 124 VVGIELSGNPAVGNFGDFI--PALNRARQSGLKVT-LHCGEVCNPEEVLEMLNFKPERIG 180
V+ I+ G +G FG I P LNR SG +++ H VC+P + P R G
Sbjct: 58 VILIDDMGYSDIGPFGSEIDTPNLNRLADSGYRLSNYHTTSVCSPARAALLTGLNPHRAG 117
Query: 181 HG 182
+G
Sbjct: 118 YG 119
>UniRef50_A6RK08 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 519
Score = 35.5 bits (78), Expect = 1.7
Identities = 41/173 (23%), Positives = 71/173 (41%), Gaps = 21/173 (12%)
Query: 74 ELRSTPRDTQYITKKQYIDS---IIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELS 130
EL T ++ + +KKQY I + ++E D I+ K + + G +L
Sbjct: 338 ELHQTMQEIR--SKKQYFGGMKVIYCTPRSFDRGKIEMALDECIDLKKKYQKLLCGFDLV 395
Query: 131 GNPAVGN-FGDFIPAL----NRARQSGLKVTL--HCGEVCN-----PEEVLEMLNFKPER 178
G+ +GN F+P + R L + HCGE + + + +R
Sbjct: 396 GHEEMGNELRHFVPEFLAFRRKCRDQKLDIPFIFHCGETLEVGGEVDGNLFDAILLNAKR 455
Query: 179 IGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELI 231
IGHG + ++ E + + KI +E C SN +TP+ H+ L+
Sbjct: 456 IGHGYAV-ARHPILMEIFK---EKKIAIESCPISNEVLGLTPNIAGHNLPVLL 504
>UniRef50_A3IDU1 Cluster: Putative 5'-3' exonuclease; n=1;
Bacillus sp. B14905|Rep: Putative 5'-3'
exonuclease - Bacillus sp. B14905
Length = 295
Score = 34.7 bits (76), Expect = 3.0
Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 4/42 (9%)
Query: 197 IALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVV 238
+A Q+ +P+E LTS I P+YE H FKE+ E+G +++
Sbjct: 247 LATIQTDVPIEADLTS----LILPNYEPHIFKEIEESGYTLI 284
>UniRef50_Q9VVK5 Cluster: CG5992-PA, isoform A; n=6;
Schizophora|Rep: CG5992-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 553
Score = 34.7 bits (76), Expect = 3.0
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 16/145 (11%)
Query: 120 HPDTVVGIELSGNPAVGN-FGDFIPALNRARQSGLKVTLHCGEV-----CNPEEVLEMLN 173
+P+ V G +L G +G DF+ L + + H GE E +++ +
Sbjct: 348 YPEFVAGFDLVGQEEMGRPLRDFVDEL-LSIPDDIDFYFHAGETNWFGSTVDENLIDAIL 406
Query: 174 FKPERIGHGVCI--HPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYESHHFKELI 231
+RIGHG + HP L + + +EV SN ++ D+ +H
Sbjct: 407 LGTKRIGHGFGLVKHPV------VLDMLKKLNVAIEVNPISNQVLQLVSDFRNHPCSHFF 460
Query: 232 EAGLSVVLCTDDKGVF-ATSLSQEY 255
G VV+ +DD + AT L+ ++
Sbjct: 461 ADGYPVVISSDDPSFWKATPLTHDF 485
>UniRef50_A7ER99 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 1010
Score = 34.7 bits (76), Expect = 3.0
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Query: 206 VEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATS---LSQEYRLCAESF 262
+ V ++ N + YE + F + GL+V L TDD FA + L +EY + A+ +
Sbjct: 692 IGVAMSPLSNNALFLAYERNPFLSYFKRGLNVSLSTDDPLQFAFTKEPLIEEYSVAAQIY 751
Query: 263 ALTRIQVAKLSLDAAQCIFSEANIRELIIG 292
L+ + + +L+ ++ + E ++++ +G
Sbjct: 752 KLSAVDMCELAKNSVKQSGFEHSVKQRWLG 781
>UniRef50_A7E4Y0 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 621
Score = 34.7 bits (76), Expect = 3.0
Identities = 45/216 (20%), Positives = 84/216 (38%), Gaps = 23/216 (10%)
Query: 41 FSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITKKQYIDSIIRAMEA 100
F +SL S + E L E+ + ++ + QY + I R+ +
Sbjct: 298 FMATNSLKSDDGTRTIGNEGILNIINEE--LHRTMQEIRNNKQYFGGMKVIYCTPRSFDR 355
Query: 101 SQLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPAL----NRARQSGLKV 155
Q +E D I+ K + + G +L G+ +GN F+P + R L +
Sbjct: 356 GQ---IEVALDECIDLKKKYQKLLCGFDLVGHEEMGNELRHFVPEFLAFRRKCRDQKLDI 412
Query: 156 TL--HCGEVCNPEE-----VLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSK-IPVE 207
HCGE + + + + + +RIGHG + + + + K I +E
Sbjct: 413 PFLFHCGETLSVGDKVDGNLFDAILLNAKRIGHGYAV-----ARHPILMQIFKEKNIAIE 467
Query: 208 VCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDD 243
C SN +TP+ H+ L+ + + +D+
Sbjct: 468 SCPISNEVLGLTPNIAGHNLPILLANDVPCTINSDN 503
>UniRef50_Q3M5Z5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Nostocaceae|Rep: Short-chain dehydrogenase/reductase
SDR - Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length = 1874
Score = 34.3 bits (75), Expect = 3.9
Identities = 16/37 (43%), Positives = 24/37 (64%)
Query: 136 GNFGDFIPALNRARQSGLKVTLHCGEVCNPEEVLEML 172
G GD A+N+ +Q+G KV + +V NPE+V +ML
Sbjct: 1504 GVVGDTQVAINQLQQAGAKVLVVTADVSNPEDVAQML 1540
>UniRef50_Q1YG22 Cluster: Alpha-amylase family protein; n=3;
Rhizobiales|Rep: Alpha-amylase family protein -
Aurantimonas sp. SI85-9A1
Length = 721
Score = 34.3 bits (75), Expect = 3.9
Identities = 14/35 (40%), Positives = 22/35 (62%)
Query: 132 NPAVGNFGDFIPALNRARQSGLKVTLHCGEVCNPE 166
+P +GNF DF ++RAR GL+V + C+P+
Sbjct: 352 HPELGNFEDFARLVSRARDHGLEVAIDFAIQCSPD 386
>UniRef50_A0R7F0 Cluster: Amidohydrolase family protein; n=2;
Actinomycetales|Rep: Amidohydrolase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 415
Score = 34.3 bits (75), Expect = 3.9
Identities = 34/141 (24%), Positives = 66/141 (46%), Gaps = 14/141 (9%)
Query: 145 LNRARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKI 204
++ A + GL+VT+H + E +E + + HGV + P T+ + L +
Sbjct: 234 IDTAHERGLRVTVHTTQQAAAREAIEA---GADGLEHGVTVEPI---TDHALVDLMLER- 286
Query: 205 PVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTD---DKGVFATSLSQEYRLCAES 261
T ++ PD + K++ +AG+++V+ +D +G+F + +E L +
Sbjct: 287 DTTYTPTLWIDDAAHPDTRG-NLKKVADAGVTIVMGSDTFSGRGLFGANTLEEAELMVAA 345
Query: 262 FALTRIQ--VAKLSLDAAQCI 280
+T +Q VA S A QC+
Sbjct: 346 -GMTPLQSLVAGTSAAARQCV 365
>UniRef50_Q22TE2 Cluster: Adenosine/AMP deaminase family protein;
n=1; Tetrahymena thermophila SB210|Rep: Adenosine/AMP
deaminase family protein - Tetrahymena thermophila SB210
Length = 746
Score = 34.3 bits (75), Expect = 3.9
Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 14/139 (10%)
Query: 142 IPALNRARQS-GL---KVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETWI 197
I +LN R+ GL K HCGE + + ++ + I HG+ + +
Sbjct: 551 ISSLNLLRKERGLNTFKFRPHCGEAGDIDHLICAFLLS-DSINHGILLEQN-----PVLL 604
Query: 198 ALCQSKIPVEVCLTSNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATS---LSQE 254
L K + + ++ N K+ Y F + + G++V L TDD + T+ L +E
Sbjct: 605 YLYYLK-QIGLAMSPLSNNKLFLKYAKSPFFDFFKIGINVTLSTDDPLILHTTNDPLLEE 663
Query: 255 YRLCAESFALTRIQVAKLS 273
Y + A+ + L+ + +A+L+
Sbjct: 664 YAISAQIWDLSSVDIAELA 682
>UniRef50_UPI000155C584 Cluster: PREDICTED: similar to helicase B;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
helicase B - Ornithorhynchus anatinus
Length = 1045
Score = 33.9 bits (74), Expect = 5.2
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 166 EEVLEMLNFKPERIGHGVCIHPKYG--GTEETWIALCQSKIPVEVCLTSNVNTKIT 219
E++ E L+ +P + G + ++G G E TW ALCQ K +E N IT
Sbjct: 238 EKMQETLDSEPWKFGFSKITYREFGLVGCEATWTALCQCKALLETIPVLQKNALIT 293
>UniRef50_Q22YL6 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 399
Score = 33.9 bits (74), Expect = 5.2
Identities = 17/65 (26%), Positives = 33/65 (50%)
Query: 31 TRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITKKQY 90
T + + ++S A+SL + E++ E T+ +FQ + L S R T + K+Y
Sbjct: 130 TDQIVKLHMIYSKAYSLDNLKESIFQYIEETIDKFQVENKINEFLHSFQRQTDKVEAKRY 189
Query: 91 IDSII 95
+D ++
Sbjct: 190 LDQLL 194
>UniRef50_A7AV25 Cluster: JmjC transcription factor, putative; n=1;
Babesia bovis|Rep: JmjC transcription factor, putative -
Babesia bovis
Length = 754
Score = 33.9 bits (74), Expect = 5.2
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 104 QEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGEVC 163
+E +E A ++ R ++ PD VV + V + +F+ A RA SGL V +C E C
Sbjct: 321 REGDEFAMYSL-RIQVPPDVVVSNGIPVYRLVQSANEFVFAWPRAFHSGLNVGYNCNEAC 379
Query: 164 N 164
N
Sbjct: 380 N 380
>UniRef50_A1Z9F9 Cluster: CG13335-PA, isoform A; n=5;
Sophophora|Rep: CG13335-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 410
Score = 33.9 bits (74), Expect = 5.2
Identities = 40/183 (21%), Positives = 75/183 (40%), Gaps = 11/183 (6%)
Query: 30 DTRNLSECFQVFSIAHSLTSTSEALVMATELTLQEFQEDGCCYIELRSTPRDTQYITK-K 88
D R+ +E + F + S A+++A + ++ ++L QY K K
Sbjct: 120 DARDYAEASR-FKLMQSFLGV--AIILALLSLVASQAQNSSQSMDLYILQNQRQYDAKIK 176
Query: 89 QYIDSI--IRAMEASQLQEVEEIAD---IAIERHKIHPDTVVGIELSGNPAVGNFGDFIP 143
Q D + + + Q+ ++ AD + +E+ H D ++ I+ V N+ IP
Sbjct: 177 QLADELANFKQLFQKQINALDVQADSMQLKLEQASAHLDPIILIDSWSKQCVQNYSVTIP 236
Query: 144 ALNRARQSGLKVTLHCGEVCN-PEEVLEML-NFKPERIGHGVCIHPKYGGTEETWIALCQ 201
+ AR S +K + N PE L N+ + +G+ K T + LC
Sbjct: 237 TITVARDSIIKCKESISGILNAPESTYNTLNNYYKNNVKNGLAQCLKLHPTAQLNYTLCV 296
Query: 202 SKI 204
+K+
Sbjct: 297 TKV 299
>UniRef50_Q59GS5 Cluster: Paxillin variant; n=6; Eutheria|Rep:
Paxillin variant - Homo sapiens (Human)
Length = 713
Score = 33.9 bits (74), Expect = 5.2
Identities = 26/74 (35%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 100 ASQLQEVEEIADIAIERHKIHPDTVVGIELSG------NPAVGNFGDFIPALNRARQSGL 153
A QEV E A +A++R I PDT E G P G G PA Q G
Sbjct: 462 ARSFQEVTEPAVVAVDRQAIFPDTWTLTEEHGLQQERPRPEPGRLGSSSPASVTTEQLGA 521
Query: 154 KVTLHCGEVCNPEE 167
K+T G V P +
Sbjct: 522 KMT-ERGSVARPTQ 534
>UniRef50_A6PKL2 Cluster: Glycyl-radical enzyme activating protein
family; n=1; Victivallis vadensis ATCC BAA-548|Rep:
Glycyl-radical enzyme activating protein family -
Victivallis vadensis ATCC BAA-548
Length = 300
Score = 33.5 bits (73), Expect = 6.9
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 102 QLQEVEEIADIAIERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLH-CG 160
QL+ VEE+ ++ + ++ GI LSG + F L RA+++GL V L CG
Sbjct: 104 QLRSVEEVISEVLKDKLFYDNSGGGITLSGGEPMAQFDFTQELLKRAKEAGLHVCLETCG 163
>UniRef50_A3ZY64 Cluster: Putative uncharacterized protein; n=1;
Blastopirellula marina DSM 3645|Rep: Putative
uncharacterized protein - Blastopirellula marina DSM
3645
Length = 702
Score = 33.5 bits (73), Expect = 6.9
Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Query: 93 SIIRAMEASQLQEVEEIADIA--IERHKIHPDTVVGIELSGNPAVGNFGDFIPALNRARQ 150
++ R +EASQL+ A A +RH + +V E S P + +FGD +PAL +
Sbjct: 427 NLARLVEASQLELAVRFAPPAPGADRHDLR---LVTFE-SPRPPLASFGDSLPALIEPLR 482
Query: 151 SGLKVTLHCGEVCNP 165
G +++ G V NP
Sbjct: 483 FGGGLSIQGGSVVNP 497
>UniRef50_A4RGE3 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 557
Score = 33.5 bits (73), Expect = 6.9
Identities = 15/50 (30%), Positives = 30/50 (60%), Gaps = 3/50 (6%)
Query: 81 DTQYITKKQYIDSIIRAMEASQLQEVEEIADIAIERHKIHPDTVVGIELS 130
D ++ K++ + +I A+ AS L+++ +++ A + HPD+V GI S
Sbjct: 404 DPGFVDKRRVLQGVIDALRASALEQISQLSGRAA---RCHPDSVTGITRS 450
>UniRef50_P53909 Cluster: Adenosine deaminase; n=10;
Saccharomycetales|Rep: Adenosine deaminase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 347
Score = 33.5 bits (73), Expect = 6.9
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 5/111 (4%)
Query: 153 LKVTLHCGEVCNPEEVLEMLNF-KPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLT 211
LK+T H GE + V + L+ + RI HG I+ +Y EE L + + + +C
Sbjct: 199 LKLTAHAGEEGPAQFVSDALDLLQVTRIDHG--INSQYD--EELLDRLSRDQTMLTICPL 254
Query: 212 SNVNTKITPDYESHHFKELIEAGLSVVLCTDDKGVFATSLSQEYRLCAESF 262
SNV ++ ++ ++ + L +DD F + Y ++ F
Sbjct: 255 SNVKLQVVQSVSELPLQKFLDRDVPFSLNSDDPAYFGGYILDVYTQVSKDF 305
>UniRef50_UPI0000E48CF5 Cluster: PREDICTED: similar to
mollusk-derived growth factor; MDGF, partial; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
mollusk-derived growth factor; MDGF, partial -
Strongylocentrotus purpuratus
Length = 531
Score = 33.1 bits (72), Expect = 9.1
Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 13/153 (8%)
Query: 112 IAIERHKIHPDTVVGIELSGNPAVGN-FGDFIPALNRARQSGLKVT--LHCGEVCNPEE- 167
+ ++ K +P+ G +L G G D+I L + G+ + H GE E
Sbjct: 357 LGMDFRKKYPEFFAGYDLVGEEDSGGPLIDYIDELLIPTKLGMDLPYFFHAGETDWEGEF 416
Query: 168 ----VLEMLNFKPERIGHGVCIHPKYGGTEETWIALCQSKIPVEVCLTSNVNTKITPDYE 223
+++ + RIGHG I K+ ET + + +E+ SN + D
Sbjct: 417 VDKNLIDAVLLNTSRIGHGYAIG-KHPVVMET---IKSKGVAIEINPISNQVLHLVHDIR 472
Query: 224 SHHFKELIEAGLSVVLCTDDKGVF-ATSLSQEY 255
H LI V++ +DD G + A LS +Y
Sbjct: 473 DHVGASLIADDYPVIISSDDPGAWEALPLSHDY 505
>UniRef50_Q4DEV2 Cluster: Putative uncharacterized protein; n=2;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 479
Score = 33.1 bits (72), Expect = 9.1
Identities = 16/60 (26%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 122 DTVVGIELSGNPAVGNFGDFIPALNRARQSGLKVTLHCGE-VCNPEEVLEMLNFKPERIG 180
D VG+EL + +G + + +N A + + + E VC + +L+++ ++PE IG
Sbjct: 331 DAAVGVELPPHQLMGVERNAVSGVNSATEKAKSIVVVNAEFVCERDSLLDVITYRPECIG 390
>UniRef50_A2DM60 Cluster: Ankyrin repeat protein, putative; n=1;
Trichomonas vaginalis G3|Rep: Ankyrin repeat protein,
putative - Trichomonas vaginalis G3
Length = 288
Score = 33.1 bits (72), Expect = 9.1
Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 8/70 (11%)
Query: 148 ARQSGLKVTLHCGEVCNPEEVLEMLNFKPERIGHGVCIHPKYGGTEETW--IALCQSKIP 205
A+ L+ LHC CN +E+ E+L IGHG I+ K E A C S
Sbjct: 11 AKDKDLQTPLHCASECNSKEIAELL------IGHGAEINSKDEEKETPLHVTAYCDSIAV 64
Query: 206 VEVCLTSNVN 215
EV + N
Sbjct: 65 AEVLILHGAN 74
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.135 0.393
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 320,613,857
Number of Sequences: 1657284
Number of extensions: 12500662
Number of successful extensions: 28397
Number of sequences better than 10.0: 182
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 81
Number of HSP's that attempted gapping in prelim test: 28114
Number of HSP's gapped (non-prelim): 243
length of query: 303
length of database: 575,637,011
effective HSP length: 100
effective length of query: 203
effective length of database: 409,908,611
effective search space: 83211448033
effective search space used: 83211448033
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 72 (33.1 bits)
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