Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001273-TA|BGIBMGA001273-PA|IPR012776|Trimethyllysine
dioxygenase, IPR003819|Taurine catabolism dioxygenase TauD/TfdA
(232 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR457265-1|CAG33546.1| 421|Homo sapiens TMLHE protein. 172 8e-43
BX276110-3|CAH71441.1| 421|Homo sapiens trimethyllysine hydroxy... 172 8e-43
AK001589-1|BAA91775.1| 421|Homo sapiens protein ( Homo sapiens ... 172 8e-43
AF373407-1|AAL01871.1| 421|Homo sapiens epsilon-trimethyllysine... 172 8e-43
BX276110-4|CAH71442.1| 376|Homo sapiens trimethyllysine hydroxy... 107 2e-23
BC025269-1|AAH25269.1| 376|Homo sapiens TMLHE protein protein. 107 2e-23
CR456812-1|CAG33093.1| 387|Homo sapiens BBOX1 protein. 95 2e-19
BC011034-1|AAH11034.1| 387|Homo sapiens butyrobetaine (gamma), ... 95 2e-19
AF082868-1|AAC64066.1| 387|Homo sapiens gamma butyrobetaine hyd... 95 2e-19
AM081894-1|CAL06040.1| 101|Homo sapiens immunoglobulin heavy ch... 32 1.9
AM083301-1|CAL07447.1| 101|Homo sapiens immunoglobulin heavy ch... 31 3.4
AM081371-1|CAL05517.1| 101|Homo sapiens immunoglobulin heavy ch... 31 3.4
AM081364-1|CAL05510.1| 101|Homo sapiens immunoglobulin heavy ch... 30 5.9
AJ556044-1|CAD88736.1| 117|Homo sapiens immunoglobulin heavy ch... 30 7.9
AJ496466-1|CAD42977.1| 119|Homo sapiens immunoglobulin heavy ch... 30 7.9
>CR457265-1|CAG33546.1| 421|Homo sapiens TMLHE protein.
Length = 421
Score = 172 bits (419), Expect = 8e-43
Identities = 91/234 (38%), Positives = 130/234 (55%), Gaps = 5/234 (2%)
Query: 1 YTFKSFNQVQPSAEATETVCKALGGIQHTIFGATWEFTTVADHADTAYTNLPLAAHNDNI 60
Y V P+ E TE + + + I+ TI+G W FT+ DTAYT L L H D
Sbjct: 187 YGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTT 246
Query: 61 YWTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGEYIER- 119
Y+ E G+Q+ HC++H GTGG T+LVDGFY A + + PE++E L+ ++ EYIE
Sbjct: 247 YFQEPCGIQVFHCLKH-EGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDV 305
Query: 120 ---RHHFTHSAPVIQIDKNTEDIKQIRFNVYDRSAMAFRSGRDCRLYYRSLKNLARYYEN 176
+H PV+ I +++ IR+N YDR+ + +Y + + L
Sbjct: 306 GECHNHMIGIGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDVVHRWYTAHRTLTIELRR 365
Query: 177 KENQWIFKLVPGLVMVIDNFRLLHGRNGFTGRRVLCGAYVSRSDWLDKARSLNL 230
EN++ KL PG V+ IDN+R+LHGR FTG R LCG Y++R D L+ AR L L
Sbjct: 366 PENEFWVKLKPGRVLFIDNWRVLHGRECFTGYRQLCGCYLTRDDVLNTARLLGL 419
>BX276110-3|CAH71441.1| 421|Homo sapiens trimethyllysine
hydroxylase, epsilon protein.
Length = 421
Score = 172 bits (419), Expect = 8e-43
Identities = 91/234 (38%), Positives = 130/234 (55%), Gaps = 5/234 (2%)
Query: 1 YTFKSFNQVQPSAEATETVCKALGGIQHTIFGATWEFTTVADHADTAYTNLPLAAHNDNI 60
Y V P+ E TE + + + I+ TI+G W FT+ DTAYT L L H D
Sbjct: 187 YGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTT 246
Query: 61 YWTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGEYIER- 119
Y+ E G+Q+ HC++H GTGG T+LVDGFY A + + PE++E L+ ++ EYIE
Sbjct: 247 YFQEPCGIQVFHCLKH-EGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDV 305
Query: 120 ---RHHFTHSAPVIQIDKNTEDIKQIRFNVYDRSAMAFRSGRDCRLYYRSLKNLARYYEN 176
+H PV+ I +++ IR+N YDR+ + +Y + + L
Sbjct: 306 GECHNHMIGIGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDVVHRWYTAHRTLTIELRR 365
Query: 177 KENQWIFKLVPGLVMVIDNFRLLHGRNGFTGRRVLCGAYVSRSDWLDKARSLNL 230
EN++ KL PG V+ IDN+R+LHGR FTG R LCG Y++R D L+ AR L L
Sbjct: 366 PENEFWVKLKPGRVLFIDNWRVLHGRECFTGYRQLCGCYLTRDDVLNTARLLGL 419
>AK001589-1|BAA91775.1| 421|Homo sapiens protein ( Homo sapiens
cDNA FLJ10727 fis, clone NT2RP3001221, weakly similar to
GAMMA-BUTYROBETAINE,2-OXOGLUTARATE DIOXYGENASE (EC
1.14.11.1). ).
Length = 421
Score = 172 bits (419), Expect = 8e-43
Identities = 91/234 (38%), Positives = 130/234 (55%), Gaps = 5/234 (2%)
Query: 1 YTFKSFNQVQPSAEATETVCKALGGIQHTIFGATWEFTTVADHADTAYTNLPLAAHNDNI 60
Y V P+ E TE + + + I+ TI+G W FT+ DTAYT L L H D
Sbjct: 187 YGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTT 246
Query: 61 YWTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGEYIER- 119
Y+ E G+Q+ HC++H GTGG T+LVDGFY A + + PE++E L+ ++ EYIE
Sbjct: 247 YFQEPCGIQVFHCLKH-EGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDV 305
Query: 120 ---RHHFTHSAPVIQIDKNTEDIKQIRFNVYDRSAMAFRSGRDCRLYYRSLKNLARYYEN 176
+H PV+ I +++ IR+N YDR+ + +Y + + L
Sbjct: 306 GECHNHMIGIGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDVVHRWYTAHRTLTIELRR 365
Query: 177 KENQWIFKLVPGLVMVIDNFRLLHGRNGFTGRRVLCGAYVSRSDWLDKARSLNL 230
EN++ KL PG V+ IDN+R+LHGR FTG R LCG Y++R D L+ AR L L
Sbjct: 366 PENEFWVKLKPGRVLFIDNWRVLHGRECFTGYRQLCGCYLTRDDVLNTARLLGL 419
>AF373407-1|AAL01871.1| 421|Homo sapiens epsilon-trimethyllysine
2-oxoglutarate dioxygenase protein.
Length = 421
Score = 172 bits (419), Expect = 8e-43
Identities = 91/234 (38%), Positives = 130/234 (55%), Gaps = 5/234 (2%)
Query: 1 YTFKSFNQVQPSAEATETVCKALGGIQHTIFGATWEFTTVADHADTAYTNLPLAAHNDNI 60
Y V P+ E TE + + + I+ TI+G W FT+ DTAYT L L H D
Sbjct: 187 YGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTT 246
Query: 61 YWTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGEYIER- 119
Y+ E G+Q+ HC++H GTGG T+LVDGFY A + + PE++E L+ ++ EYIE
Sbjct: 247 YFQEPCGIQVFHCLKH-EGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDV 305
Query: 120 ---RHHFTHSAPVIQIDKNTEDIKQIRFNVYDRSAMAFRSGRDCRLYYRSLKNLARYYEN 176
+H PV+ I +++ IR+N YDR+ + +Y + + L
Sbjct: 306 GECHNHMIGIGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDVVHRWYTAHRTLTIELRR 365
Query: 177 KENQWIFKLVPGLVMVIDNFRLLHGRNGFTGRRVLCGAYVSRSDWLDKARSLNL 230
EN++ KL PG V+ IDN+R+LHGR FTG R LCG Y++R D L+ AR L L
Sbjct: 366 PENEFWVKLKPGRVLFIDNWRVLHGRECFTGYRQLCGCYLTRDDVLNTARLLGL 419
>BX276110-4|CAH71442.1| 376|Homo sapiens trimethyllysine
hydroxylase, epsilon protein.
Length = 376
Score = 107 bits (258), Expect = 2e-23
Identities = 55/147 (37%), Positives = 80/147 (54%), Gaps = 5/147 (3%)
Query: 1 YTFKSFNQVQPSAEATETVCKALGGIQHTIFGATWEFTTVADHADTAYTNLPLAAHNDNI 60
Y V P+ E TE + + + I+ TI+G W FT+ DTAYT L L H D
Sbjct: 187 YGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTT 246
Query: 61 YWTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGEYIER- 119
Y+ E G+Q+ HC++H GTGG T+LVDGFY A + + PE++E L+ ++ EYIE
Sbjct: 247 YFQEPCGIQVFHCLKH-EGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDV 305
Query: 120 ---RHHFTHSAPVIQIDKNTEDIKQIR 143
+H PV+ I +++ IR
Sbjct: 306 GECHNHMIGIGPVLNIYPWNKELYLIR 332
>BC025269-1|AAH25269.1| 376|Homo sapiens TMLHE protein protein.
Length = 376
Score = 107 bits (258), Expect = 2e-23
Identities = 55/147 (37%), Positives = 80/147 (54%), Gaps = 5/147 (3%)
Query: 1 YTFKSFNQVQPSAEATETVCKALGGIQHTIFGATWEFTTVADHADTAYTNLPLAAHNDNI 60
Y V P+ E TE + + + I+ TI+G W FT+ DTAYT L L H D
Sbjct: 187 YGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTT 246
Query: 61 YWTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGEYIER- 119
Y+ E G+Q+ HC++H GTGG T+LVDGFY A + + PE++E L+ ++ EYIE
Sbjct: 247 YFQEPCGIQVFHCLKH-EGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDV 305
Query: 120 ---RHHFTHSAPVIQIDKNTEDIKQIR 143
+H PV+ I +++ IR
Sbjct: 306 GECHNHMIGIGPVLNIYPWNKELYLIR 332
>CR456812-1|CAG33093.1| 387|Homo sapiens BBOX1 protein.
Length = 387
Score = 95.1 bits (226), Expect = 2e-19
Identities = 65/210 (30%), Positives = 107/210 (50%), Gaps = 16/210 (7%)
Query: 21 KALGGIQHTIFGATWEFTTVADHADTAYTNLPLAAHNDNIYWTEAAGLQILHCIEHTNGT 80
K +G + T +G TW+ D + AYT L+ H D G+Q+LHCI+ T T
Sbjct: 167 KRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTV-T 225
Query: 81 GGETILVDGFYGATCLKEDHPEDYEFLTTY-----EIEGEYIERRHHFTHSAPVIQIDKN 135
GG++ +VDGF LK+++P+ ++ L++ +I +Y + H +I++D
Sbjct: 226 GGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHK--IIELDDK 283
Query: 136 TEDIKQIRFNVYDRSAMAFRSGRDCRLYYRSLKNLARYYENKENQWIFKLVPGLVMVIDN 195
+ ++ I FN R + + +Y +LK +KE+++ FK+ PG V+ DN
Sbjct: 284 GQVVR-INFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDN 342
Query: 196 FRLLHGRNGFTG----RRVLCGAYVSRSDW 221
+RLLHGR + R L GAY +DW
Sbjct: 343 WRLLHGRRSYEAGTEISRHLEGAY---ADW 369
>BC011034-1|AAH11034.1| 387|Homo sapiens butyrobetaine (gamma),
2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxyl
protein.
Length = 387
Score = 95.1 bits (226), Expect = 2e-19
Identities = 65/210 (30%), Positives = 107/210 (50%), Gaps = 16/210 (7%)
Query: 21 KALGGIQHTIFGATWEFTTVADHADTAYTNLPLAAHNDNIYWTEAAGLQILHCIEHTNGT 80
K +G + T +G TW+ D + AYT L+ H D G+Q+LHCI+ T T
Sbjct: 167 KRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTV-T 225
Query: 81 GGETILVDGFYGATCLKEDHPEDYEFLTTY-----EIEGEYIERRHHFTHSAPVIQIDKN 135
GG++ +VDGF LK+++P+ ++ L++ +I +Y + H +I++D
Sbjct: 226 GGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHK--IIELDDK 283
Query: 136 TEDIKQIRFNVYDRSAMAFRSGRDCRLYYRSLKNLARYYENKENQWIFKLVPGLVMVIDN 195
+ ++ I FN R + + +Y +LK +KE+++ FK+ PG V+ DN
Sbjct: 284 GQVVR-INFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDN 342
Query: 196 FRLLHGRNGFTG----RRVLCGAYVSRSDW 221
+RLLHGR + R L GAY +DW
Sbjct: 343 WRLLHGRRSYEAGTEISRHLEGAY---ADW 369
>AF082868-1|AAC64066.1| 387|Homo sapiens gamma butyrobetaine
hydroxylase protein.
Length = 387
Score = 95.1 bits (226), Expect = 2e-19
Identities = 65/210 (30%), Positives = 107/210 (50%), Gaps = 16/210 (7%)
Query: 21 KALGGIQHTIFGATWEFTTVADHADTAYTNLPLAAHNDNIYWTEAAGLQILHCIEHTNGT 80
K +G + T +G TW+ D + AYT L+ H D G+Q+LHCI+ T T
Sbjct: 167 KRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTV-T 225
Query: 81 GGETILVDGFYGATCLKEDHPEDYEFLTTY-----EIEGEYIERRHHFTHSAPVIQIDKN 135
GG++ +VDGF LK+++P+ ++ L++ +I +Y + H +I++D
Sbjct: 226 GGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHK--IIELDDK 283
Query: 136 TEDIKQIRFNVYDRSAMAFRSGRDCRLYYRSLKNLARYYENKENQWIFKLVPGLVMVIDN 195
+ ++ I FN R + + +Y +LK +KE+++ FK+ PG V+ DN
Sbjct: 284 GQVVR-INFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDN 342
Query: 196 FRLLHGRNGFTG----RRVLCGAYVSRSDW 221
+RLLHGR + R L GAY +DW
Sbjct: 343 WRLLHGRRSYEAGTEISRHLEGAY---ADW 369
>AM081894-1|CAL06040.1| 101|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 101
Score = 31.9 bits (69), Expect = 1.9
Identities = 18/69 (26%), Positives = 30/69 (43%), Gaps = 2/69 (2%)
Query: 47 AYTNLPLAAHNDNIYWTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEF 106
A + LP ++H + W A + L C+ +G G +T D G + D+ +D F
Sbjct: 26 ATSGLPFSSHA--MSWVRKAPGKGLECVSVISGDGEKTYYADSVKGRFTISRDNSKDTAF 83
Query: 107 LTTYEIEGE 115
L + E
Sbjct: 84 LQMNSLRAE 92
>AM083301-1|CAL07447.1| 101|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 101
Score = 31.1 bits (67), Expect = 3.4
Identities = 14/54 (25%), Positives = 24/54 (44%)
Query: 62 WTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGE 115
W A + L C+ +G+GG T D G + D+ ++ +L + GE
Sbjct: 39 WVRQAPGKGLECVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRGE 92
>AM081371-1|CAL05517.1| 101|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 101
Score = 31.1 bits (67), Expect = 3.4
Identities = 14/54 (25%), Positives = 23/54 (42%)
Query: 62 WTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGE 115
W A + L C+ +G+GG T D G + D+ E+ +L + E
Sbjct: 39 WVRQAPGKGLECVSFISGSGGSTYFADSVKGRFTISRDNSENTLYLRMNSLRAE 92
>AM081364-1|CAL05510.1| 101|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 101
Score = 30.3 bits (65), Expect = 5.9
Identities = 15/54 (27%), Positives = 24/54 (44%)
Query: 62 WTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGE 115
W A + L + T+GTGG T D G + D+P++ +L + E
Sbjct: 39 WVRQAPGKGLEWVSGTSGTGGSTYYSDSVKGRFTVSRDNPKNTLYLQMNSLRAE 92
>AJ556044-1|CAD88736.1| 117|Homo sapiens immunoglobulin heavy chain
protein.
Length = 117
Score = 29.9 bits (64), Expect = 7.9
Identities = 16/57 (28%), Positives = 24/57 (42%)
Query: 59 NIYWTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGE 115
+++W A + L + N GETI F G + ED ED +L + E
Sbjct: 33 SVHWVRQAPGKGLEWMGGLNPEDGETIYAQKFQGRVTMTEDTSEDTAYLELSSLRSE 89
>AJ496466-1|CAD42977.1| 119|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 119
Score = 29.9 bits (64), Expect = 7.9
Identities = 16/56 (28%), Positives = 23/56 (41%)
Query: 60 IYWTEAAGLQILHCIEHTNGTGGETILVDGFYGATCLKEDHPEDYEFLTTYEIEGE 115
IYW A + L + + GET+ GF G L ED D ++ + E
Sbjct: 34 IYWVRQAPGKGLVWMSSYDPDEGETVFAQGFRGRITLSEDTATDTSYMELRNLRSE 89
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.137 0.428
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 36,477,469
Number of Sequences: 224733
Number of extensions: 1611599
Number of successful extensions: 8761
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 8728
Number of HSP's gapped (non-prelim): 15
length of query: 232
length of database: 73,234,838
effective HSP length: 88
effective length of query: 144
effective length of database: 53,458,334
effective search space: 7698000096
effective search space used: 7698000096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 64 (29.9 bits)
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