BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001268-TA|BGIBMGA001268-PA|IPR011009|Protein kinase-like, IPR008973|C2 calcium/lipid-binding region, CaLB, IPR000403|Phosphatidylinositol 3- and 4-kinase, catalytic, IPR000341|Phosphoinositide 3-kinase, ras-binding, IPR002420|Phosphoinositide 3-kinase, C2, IPR001263|Phosphoinositide 3-kinase accessory region PIK, IPR001683|Phox-like (1505 letters) Database: fruitfly 52,641 sequences; 24,830,863 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AY058587-1|AAL13816.1| 1876|Drosophila melanogaster LD28067p pro... 757 0.0 AE014296-2027|AAF50012.1| 1876|Drosophila melanogaster CG11621-P... 757 0.0 AE014296-2026|AAF50011.1| 1876|Drosophila melanogaster CG11621-P... 757 0.0 U52192-1|AAC47117.1| 1876|Drosophila melanogaster phosphoinositi... 753 0.0 X92892-1|CAA63485.1| 1876|Drosophila melanogaster phosphoinositi... 751 0.0 Y09070-1|CAA70291.1| 1088|Drosophila melanogaster phosphoinositi... 202 2e-51 DQ792600-2|ABG88076.1| 1088|Drosophila melanogaster PI-3 kinase ... 202 2e-51 DQ792600-1|ABG88075.1| 1088|Drosophila melanogaster PI-3 kinase ... 202 2e-51 DQ792599-2|ABG88074.1| 1088|Drosophila melanogaster PI-3 kinase ... 202 2e-51 DQ792599-1|ABG88073.1| 1088|Drosophila melanogaster PI-3 kinase ... 202 2e-51 BT003173-1|AAO24928.1| 1088|Drosophila melanogaster SD05105p pro... 202 2e-51 AE014297-2834|AAN14359.1| 1088|Drosophila melanogaster CG4141-PB... 202 2e-51 AE014297-2833|AAF55792.1| 1088|Drosophila melanogaster CG4141-PA... 202 2e-51 AY113648-1|AAM29653.1| 1308|Drosophila melanogaster SD12145p pro... 129 3e-29 AL121804-6|CAB65858.1| 2160|Drosophila melanogaster EG:BACR7C10.... 129 3e-29 AE014298-425|AAF45800.2| 2178|Drosophila melanogaster CG10260-PB... 129 3e-29 X99912-1|CAA68185.1| 949|Drosophila melanogaster 1-phosphatidyl... 124 1e-27 AY058362-1|AAL13591.1| 949|Drosophila melanogaster GH13170p pro... 124 1e-27 AE013599-3631|AAF47030.2| 949|Drosophila melanogaster CG5373-PA... 124 1e-27 AY052049-1|AAK93473.1| 1674|Drosophila melanogaster LP07057p pro... 107 9e-23 AF242375-1|AAK27793.2| 1338|Drosophila melanogaster phosphatidyl... 107 9e-23 AE014296-82|AAN11438.1| 1338|Drosophila melanogaster CG7004-PC, ... 107 9e-23 AE014296-81|AAN11437.1| 1674|Drosophila melanogaster CG7004-PB, ... 107 9e-23 AE014296-80|AAF47375.2| 1674|Drosophila melanogaster CG7004-PA, ... 107 9e-23 AY069275-1|AAL39420.1| 455|Drosophila melanogaster GM10438p pro... 53 3e-06 AY052068-1|AAK93492.1| 760|Drosophila melanogaster SD02269p pro... 53 3e-06 AE014134-2272|AAF53237.1| 2470|Drosophila melanogaster CG5092-PA... 53 3e-06 U34925-2|AAC46881.1| 2354|Drosophila melanogaster MEI-41 protein. 50 2e-05 AY282465-1|AAQ22732.1| 2517|Drosophila melanogaster Mei-41 protein. 50 2e-05 AE014298-2397|AAF48604.2| 2517|Drosophila melanogaster CG4252-PA... 50 2e-05 BT011117-1|AAR82784.1| 1157|Drosophila melanogaster LD17186p pro... 38 0.14 AY395750-1|AAR89513.1| 1199|Drosophila melanogaster ATM protein ... 38 0.14 AY113192-1|AAM29197.1| 574|Drosophila melanogaster AT01448p pro... 38 0.14 AE014298-963|AAF46207.2| 3218|Drosophila melanogaster CG32743-PA... 38 0.14 AE014297-1966|ABI31168.1| 2767|Drosophila melanogaster CG6535-PB... 38 0.14 AJ556818-1|CAD89223.1| 2162|Drosophila melanogaster SMG1 protein... 37 0.25 >AY058587-1|AAL13816.1| 1876|Drosophila melanogaster LD28067p protein. Length = 1876 Score = 757 bits (1871), Expect = 0.0 Identities = 480/1226 (39%), Positives = 641/1226 (52%), Gaps = 124/1226 (10%) Query: 346 RSTTNKLYDSIVKIRTRNYDSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKYPP 405 R T +LY+ I RT D E F M +VR ++ + D TN GHV+AA Y Sbjct: 502 RKTCTRLYELISDQRTD--DPELLEFYHMVKEVRARYPHDDAPTNVGHVVAAEFNYHYMM 559 Query: 406 NTSIKILVHHAHSD-------------------EPITFTSDVESKVEHVILTVVCSLDED 446 +TSIK++VH A + P+TFT D++S V V+ + SL+ Sbjct: 560 DTSIKVIVHPALNTLQSTVLAASMGKEQVKGYGMPVTFTCDIDSVVAQVVAQALASLEGQ 619 Query: 447 IREDMSGYMLRVRGAKEYLTPGSSLSEYDYIRECVRLEKDVTL--CLHEGRD-STLARTE 503 ++ ++ Y ++ G E+L P S LS+ + + +LEKDV L CL + +ARTE Sbjct: 620 VKGTVTDYAVKPIGLLEWLAPTSRLSQLECVHNSFQLEKDVHLGLCLSTAANMQAIARTE 679 Query: 504 RDDAKDSHLTLDDLFPAQGATPMLSFDNLSILLETLEGEL----SRAIGVTSAEG-SCSP 558 RDD D+ L + L P + P++++DN+ IL+ETLE E+ S A GV SCS Sbjct: 680 RDDEHDADLLPEHLLPNE-VVPIVTYDNMMILIETLEMEIDKLESAADGVPGRSVVSCS- 737 Query: 559 KAVFQAVKAICALAGGVETLHVTHTLNAFAQACTAQG---ANNVVRPEIEREQGAYCSVS 615 V QAVKAICAL G ++T+ + + + C + + PEI + G Y V Sbjct: 738 -GVVQAVKAICALLGSIDTMEIARCVADLKRICEVEQKKYSTGASNPEIVSDYGDYAQVV 796 Query: 616 LAAGSRRDCVSLQGGRVRDAVXXXXXXXXXXXXXDFRLADAHYQAPANPAKAVPAHTISE 675 L S + + ++ +RDAV FR+A + + P +P +S+ Sbjct: 797 LRPRSMLEQIKVKCNELRDAVQELVELYANV----FRVAFS-VKTPDYSTTPIPISCVSK 851 Query: 676 TTLFCIEAVHCLPLCWSHDEYMFHAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWL 735 + CI +H W D+Y QI +GTR L S GG +PR+ F WL Sbjct: 852 PIVVCISCLHRPLPNWKFDDYSLCVQIVYGTRLLSKPNVLTCSNDTSGGLFPRLNFSAWL 911 Query: 736 NLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWA 795 + P+ TLPRE+RL L+G+ Q +E P A+ +G+ ELGW Sbjct: 912 TFDQHPICTLPREARLTFVLYGK-------QAASEGEP----NADQNGERRQVTTELGWC 960 Query: 796 ALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXX-VVNIEIPLYAHTGVK 854 ++QLFDF ++ G Y+L LWP D+ V++IE+P Y ++ Sbjct: 961 SIQLFDFKRVMICGPYLLSLWPPMTDKMLGPAPARGCHPQPDFCPVLSIEVPPYGGR-IE 1019 Query: 855 WTSGEEDKQKNISLKDLPSFD--SLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYL 912 + +E K P +D SLD + Q +LL E G TE REV WEKR YL Sbjct: 1020 FPEHQEVP------KPAPHYDFASLDANLQEELLDTAELG--YTGATERREVFWEKRLYL 1071 Query: 913 VQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKL 972 P ALP VL AA +W + L LL W SPL ++ LLLP +PD VRE A + Sbjct: 1072 QSYPNALPKVLHAAHSWDYANLIDLHALLHSWAPLSPLQSLELLLPRYPDAKVREKAVEW 1131 Query: 973 LNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIP 1032 +++M +D L LPQL Q+L+H+TY +WLLVHSLP+ Sbjct: 1132 ISKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLSKCLESPRFAHHMYWLLVHSLPD-- 1189 Query: 1033 QAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKS 1092 PH ++ E+ T R +MLRAL+ ICGE + + + Q + + Sbjct: 1190 -DPHNSIGAAMVDQEYDESQVTQVRYYR--RNKMMLRALMAICGEKMLQRFMYQHRMCQK 1246 Query: 1093 LCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSN 1152 L +A SVK AKE QPT LPL V + V++C+YF+SN Sbjct: 1247 LTTIAESVKEAKESMRQKSLAAGMDEVHQDLLEQPTCLPLGPELEVTGVSVRNCSYFNSN 1306 Query: 1153 TLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPT 1212 TLPLKINF+G D +PA+FK GDDL+QD L +Q+I+IM+ +WL LDL+MVTF +PT Sbjct: 1307 TLPLKINFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTFNCVPT 1366 Query: 1213 SNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCA 1272 GMIE+V+EAETLR IQ E GLTGSFKD+PIAEWL K NPS LEYQ A NFT SCA Sbjct: 1367 GYKSGMIELVSEAETLRKIQVECGLTGSFKDRPIAEWLGKQNPSPLEYQSAVRNFTLSCA 1426 Query: 1273 GYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTH 1332 GYSVATY+LGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR DR PFVLT Sbjct: 1427 GYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR----DRTPFVLTS 1482 Query: 1333 DMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGSERTVAGGRP 1392 DM YVINGG++P+ F +FV+LCC AFNIVR + D +L A Sbjct: 1483 DMAYVINGGDKPSTDFHYFVDLCCRAFNIVRKNADLLLHTLA------------------ 1524 Query: 1393 QMSLSGVPGVTSAAVSYVRXXXXXXXXXXXXXXXXXRLIHSSLKSNMTQ----------- 1441 M+ +G+PGV S AV YVR ++I SSLKS TQ Sbjct: 1525 HMATAGMPGVNSNAVQYVRRALLPSQSNPEAAATFAKMIQSSLKSWFTQFNFFLHNLAQM 1584 Query: 1442 -------EGRLVSVECLGYEKRYDP----------EKHY------VYALRIYRLGQATPS 1478 G L+S Y + D +KHY +Y L + R GQ P+ Sbjct: 1585 RFTPDEGSGELLSFVPRKYTMQQDGRLKIVKVVCFQKHYSMEKFYMYILEVTRHGQPDPT 1644 Query: 1479 VLYRSYKHFTELYQKICLHFPLAKVH 1504 L+RSY+ FTE +QK+C+HFPL K+H Sbjct: 1645 HLFRSYREFTEFHQKLCMHFPLVKLH 1670 Score = 50.8 bits (116), Expect = 1e-05 Identities = 38/96 (39%), Positives = 52/96 (54%), Gaps = 12/96 (12%) Query: 231 VSIGSNESNDTVGSLPKSMN-LIDFGGRNPNGSQGSVRVSVLEAFDPLLTEQSNPEYAVG 289 VS S+ N+ S+P+ N LID + + RVSVLEAFDPLL + + + A Sbjct: 316 VSSSSHTGNNGHSSVPRRGNDLIDLNHEDYS------RVSVLEAFDPLLNDNTGNDTA-- 367 Query: 290 SECSSSVYEEYDPLDFLY-GETEMR-ETPVYGTVGK 323 S+S Y EYDP DFLY G+ + P+Y V + Sbjct: 368 -SDSTSYYAEYDPFDFLYSGDAATQYSDPMYEAVNR 402 >AE014296-2027|AAF50012.1| 1876|Drosophila melanogaster CG11621-PC, isoform C protein. Length = 1876 Score = 757 bits (1871), Expect = 0.0 Identities = 480/1226 (39%), Positives = 641/1226 (52%), Gaps = 124/1226 (10%) Query: 346 RSTTNKLYDSIVKIRTRNYDSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKYPP 405 R T +LY+ I RT D E F M +VR ++ + D TN GHV+AA Y Sbjct: 502 RKTCTRLYELISDQRTD--DPELLEFYHMVKEVRARYPHDDAPTNVGHVVAAEFNYHYMM 559 Query: 406 NTSIKILVHHAHSD-------------------EPITFTSDVESKVEHVILTVVCSLDED 446 +TSIK++VH A + P+TFT D++S V V+ + SL+ Sbjct: 560 DTSIKVIVHPALNTLQSTVLAASMGKEQVKGYGMPVTFTCDIDSVVAQVVAQALASLEGQ 619 Query: 447 IREDMSGYMLRVRGAKEYLTPGSSLSEYDYIRECVRLEKDVTL--CLHEGRD-STLARTE 503 ++ ++ Y ++ G E+L P S LS+ + + +LEKDV L CL + +ARTE Sbjct: 620 VKGTVTDYAVKPIGLLEWLAPTSRLSQLECVHNSFQLEKDVHLGLCLSTAANMQAIARTE 679 Query: 504 RDDAKDSHLTLDDLFPAQGATPMLSFDNLSILLETLEGEL----SRAIGVTSAEG-SCSP 558 RDD D+ L + L P + P++++DN+ IL+ETLE E+ S A GV SCS Sbjct: 680 RDDEHDADLLPEHLLPNE-VVPIVTYDNMMILIETLEMEIDKLESAADGVPGRSVVSCS- 737 Query: 559 KAVFQAVKAICALAGGVETLHVTHTLNAFAQACTAQG---ANNVVRPEIEREQGAYCSVS 615 V QAVKAICAL G ++T+ + + + C + + PEI + G Y V Sbjct: 738 -GVVQAVKAICALLGSIDTMEIARCVADLKRICEVEQKKYSTGASNPEIVSDYGDYAQVV 796 Query: 616 LAAGSRRDCVSLQGGRVRDAVXXXXXXXXXXXXXDFRLADAHYQAPANPAKAVPAHTISE 675 L S + + ++ +RDAV FR+A + + P +P +S+ Sbjct: 797 LRPRSMLEQIKVKCNELRDAVQELVELYANV----FRVAFS-VKTPDYSTTPIPISCVSK 851 Query: 676 TTLFCIEAVHCLPLCWSHDEYMFHAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWL 735 + CI +H W D+Y QI +GTR L S GG +PR+ F WL Sbjct: 852 PIVVCISCLHRPLPNWKFDDYSLCVQIVYGTRLLSKPNVLTCSNDTSGGLFPRLNFSAWL 911 Query: 736 NLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWA 795 + P+ TLPRE+RL L+G+ Q +E P A+ +G+ ELGW Sbjct: 912 TFDQHPICTLPREARLTFVLYGK-------QAASEGEP----NADQNGERRQVTTELGWC 960 Query: 796 ALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXX-VVNIEIPLYAHTGVK 854 ++QLFDF ++ G Y+L LWP D+ V++IE+P Y ++ Sbjct: 961 SIQLFDFKRVMICGPYLLSLWPPMTDKMLGPAPARGCHPQPDFCPVLSIEVPPYGGR-IE 1019 Query: 855 WTSGEEDKQKNISLKDLPSFD--SLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYL 912 + +E K P +D SLD + Q +LL E G TE REV WEKR YL Sbjct: 1020 FPEHQEVP------KPAPHYDFASLDANLQEELLDTAELG--YTGATERREVFWEKRLYL 1071 Query: 913 VQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKL 972 P ALP VL AA +W + L LL W SPL ++ LLLP +PD VRE A + Sbjct: 1072 QSYPNALPKVLHAAHSWDYANLIDLHALLHSWAPLSPLQSLELLLPRYPDAKVREKAVEW 1131 Query: 973 LNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIP 1032 +++M +D L LPQL Q+L+H+TY +WLLVHSLP+ Sbjct: 1132 ISKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLSKCLESPRFAHHMYWLLVHSLPD-- 1189 Query: 1033 QAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKS 1092 PH ++ E+ T R +MLRAL+ ICGE + + + Q + + Sbjct: 1190 -DPHNSIGAAMVDQEYDESQVTQVRYYR--RNKMMLRALMAICGEKMLQRFMYQHRMCQK 1246 Query: 1093 LCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSN 1152 L +A SVK AKE QPT LPL V + V++C+YF+SN Sbjct: 1247 LTTIAESVKEAKESMRQKSLAAGMDEVHQDLLEQPTCLPLGPELEVTGVSVRNCSYFNSN 1306 Query: 1153 TLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPT 1212 TLPLKINF+G D +PA+FK GDDL+QD L +Q+I+IM+ +WL LDL+MVTF +PT Sbjct: 1307 TLPLKINFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTFNCVPT 1366 Query: 1213 SNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCA 1272 GMIE+V+EAETLR IQ E GLTGSFKD+PIAEWL K NPS LEYQ A NFT SCA Sbjct: 1367 GYKSGMIELVSEAETLRKIQVECGLTGSFKDRPIAEWLGKQNPSPLEYQSAVRNFTLSCA 1426 Query: 1273 GYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTH 1332 GYSVATY+LGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR DR PFVLT Sbjct: 1427 GYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR----DRTPFVLTS 1482 Query: 1333 DMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGSERTVAGGRP 1392 DM YVINGG++P+ F +FV+LCC AFNIVR + D +L A Sbjct: 1483 DMAYVINGGDKPSTDFHYFVDLCCRAFNIVRKNADLLLHTLA------------------ 1524 Query: 1393 QMSLSGVPGVTSAAVSYVRXXXXXXXXXXXXXXXXXRLIHSSLKSNMTQ----------- 1441 M+ +G+PGV S AV YVR ++I SSLKS TQ Sbjct: 1525 HMATAGMPGVNSNAVQYVRRALLPSQSNPEAAATFAKMIQSSLKSWFTQFNFFLHNLAQM 1584 Query: 1442 -------EGRLVSVECLGYEKRYDP----------EKHY------VYALRIYRLGQATPS 1478 G L+S Y + D +KHY +Y L + R GQ P+ Sbjct: 1585 RFTPDEGSGELLSFVPRKYTMQQDGRLKIVKVVCFQKHYSMEKFYMYILEVTRHGQPDPT 1644 Query: 1479 VLYRSYKHFTELYQKICLHFPLAKVH 1504 L+RSY+ FTE +QK+C+HFPL K+H Sbjct: 1645 HLFRSYREFTEFHQKLCMHFPLVKLH 1670 Score = 50.8 bits (116), Expect = 1e-05 Identities = 38/96 (39%), Positives = 52/96 (54%), Gaps = 12/96 (12%) Query: 231 VSIGSNESNDTVGSLPKSMN-LIDFGGRNPNGSQGSVRVSVLEAFDPLLTEQSNPEYAVG 289 VS S+ N+ S+P+ N LID + + RVSVLEAFDPLL + + + A Sbjct: 316 VSSSSHTGNNGHSSVPRRGNDLIDLNHEDYS------RVSVLEAFDPLLNDNTGNDTA-- 367 Query: 290 SECSSSVYEEYDPLDFLY-GETEMR-ETPVYGTVGK 323 S+S Y EYDP DFLY G+ + P+Y V + Sbjct: 368 -SDSTSYYAEYDPFDFLYSGDAATQYSDPMYEAVNR 402 >AE014296-2026|AAF50011.1| 1876|Drosophila melanogaster CG11621-PA, isoform A protein. Length = 1876 Score = 757 bits (1871), Expect = 0.0 Identities = 480/1226 (39%), Positives = 641/1226 (52%), Gaps = 124/1226 (10%) Query: 346 RSTTNKLYDSIVKIRTRNYDSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKYPP 405 R T +LY+ I RT D E F M +VR ++ + D TN GHV+AA Y Sbjct: 502 RKTCTRLYELISDQRTD--DPELLEFYHMVKEVRARYPHDDAPTNVGHVVAAEFNYHYMM 559 Query: 406 NTSIKILVHHAHSD-------------------EPITFTSDVESKVEHVILTVVCSLDED 446 +TSIK++VH A + P+TFT D++S V V+ + SL+ Sbjct: 560 DTSIKVIVHPALNTLQSTVLAASMGKEQVKGYGMPVTFTCDIDSVVAQVVAQALASLEGQ 619 Query: 447 IREDMSGYMLRVRGAKEYLTPGSSLSEYDYIRECVRLEKDVTL--CLHEGRD-STLARTE 503 ++ ++ Y ++ G E+L P S LS+ + + +LEKDV L CL + +ARTE Sbjct: 620 VKGTVTDYAVKPIGLLEWLAPTSRLSQLECVHNSFQLEKDVHLGLCLSTAANMQAIARTE 679 Query: 504 RDDAKDSHLTLDDLFPAQGATPMLSFDNLSILLETLEGEL----SRAIGVTSAEG-SCSP 558 RDD D+ L + L P + P++++DN+ IL+ETLE E+ S A GV SCS Sbjct: 680 RDDEHDADLLPEHLLPNE-VVPIVTYDNMMILIETLEMEIDKLESAADGVPGRSVVSCS- 737 Query: 559 KAVFQAVKAICALAGGVETLHVTHTLNAFAQACTAQG---ANNVVRPEIEREQGAYCSVS 615 V QAVKAICAL G ++T+ + + + C + + PEI + G Y V Sbjct: 738 -GVVQAVKAICALLGSIDTMEIARCVADLKRICEVEQKKYSTGASNPEIVSDYGDYAQVV 796 Query: 616 LAAGSRRDCVSLQGGRVRDAVXXXXXXXXXXXXXDFRLADAHYQAPANPAKAVPAHTISE 675 L S + + ++ +RDAV FR+A + + P +P +S+ Sbjct: 797 LRPRSMLEQIKVKCNELRDAVQELVELYANV----FRVAFS-VKTPDYSTTPIPISCVSK 851 Query: 676 TTLFCIEAVHCLPLCWSHDEYMFHAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWL 735 + CI +H W D+Y QI +GTR L S GG +PR+ F WL Sbjct: 852 PIVVCISCLHRPLPNWKFDDYSLCVQIVYGTRLLSKPNVLTCSNDTSGGLFPRLNFSAWL 911 Query: 736 NLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWA 795 + P+ TLPRE+RL L+G+ Q +E P A+ +G+ ELGW Sbjct: 912 TFDQHPICTLPREARLTFVLYGK-------QAASEGEP----NADQNGERRQVTTELGWC 960 Query: 796 ALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXX-VVNIEIPLYAHTGVK 854 ++QLFDF ++ G Y+L LWP D+ V++IE+P Y ++ Sbjct: 961 SIQLFDFKRVMICGPYLLSLWPPMTDKMLGPAPARGCHPQPDFCPVLSIEVPPYGGR-IE 1019 Query: 855 WTSGEEDKQKNISLKDLPSFD--SLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYL 912 + +E K P +D SLD + Q +LL E G TE REV WEKR YL Sbjct: 1020 FPEHQEVP------KPAPHYDFASLDANLQEELLDTAELG--YTGATERREVFWEKRLYL 1071 Query: 913 VQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKL 972 P ALP VL AA +W + L LL W SPL ++ LLLP +PD VRE A + Sbjct: 1072 QSYPNALPKVLHAAHSWDYANLIDLHALLHSWAPLSPLQSLELLLPRYPDAKVREKAVEW 1131 Query: 973 LNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIP 1032 +++M +D L LPQL Q+L+H+TY +WLLVHSLP+ Sbjct: 1132 ISKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLSKCLESPRFAHHMYWLLVHSLPD-- 1189 Query: 1033 QAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKS 1092 PH ++ E+ T R +MLRAL+ ICGE + + + Q + + Sbjct: 1190 -DPHNSIGAAMVDQEYDESQVTQVRYYR--RNKMMLRALMAICGEKMLQRFMYQHRMCQK 1246 Query: 1093 LCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSN 1152 L +A SVK AKE QPT LPL V + V++C+YF+SN Sbjct: 1247 LTTIAESVKEAKESMRQKSLAAGMDEVHQDLLEQPTCLPLGPELEVTGVSVRNCSYFNSN 1306 Query: 1153 TLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPT 1212 TLPLKINF+G D +PA+FK GDDL+QD L +Q+I+IM+ +WL LDL+MVTF +PT Sbjct: 1307 TLPLKINFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTFNCVPT 1366 Query: 1213 SNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCA 1272 GMIE+V+EAETLR IQ E GLTGSFKD+PIAEWL K NPS LEYQ A NFT SCA Sbjct: 1367 GYKSGMIELVSEAETLRKIQVECGLTGSFKDRPIAEWLGKQNPSPLEYQSAVRNFTLSCA 1426 Query: 1273 GYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTH 1332 GYSVATY+LGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR DR PFVLT Sbjct: 1427 GYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR----DRTPFVLTS 1482 Query: 1333 DMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGSERTVAGGRP 1392 DM YVINGG++P+ F +FV+LCC AFNIVR + D +L A Sbjct: 1483 DMAYVINGGDKPSTDFHYFVDLCCRAFNIVRKNADLLLHTLA------------------ 1524 Query: 1393 QMSLSGVPGVTSAAVSYVRXXXXXXXXXXXXXXXXXRLIHSSLKSNMTQ----------- 1441 M+ +G+PGV S AV YVR ++I SSLKS TQ Sbjct: 1525 HMATAGMPGVNSNAVQYVRRALLPSQSNPEAAATFAKMIQSSLKSWFTQFNFFLHNLAQM 1584 Query: 1442 -------EGRLVSVECLGYEKRYDP----------EKHY------VYALRIYRLGQATPS 1478 G L+S Y + D +KHY +Y L + R GQ P+ Sbjct: 1585 RFTPDEGSGELLSFVPRKYTMQQDGRLKIVKVVCFQKHYSMEKFYMYILEVTRHGQPDPT 1644 Query: 1479 VLYRSYKHFTELYQKICLHFPLAKVH 1504 L+RSY+ FTE +QK+C+HFPL K+H Sbjct: 1645 HLFRSYREFTEFHQKLCMHFPLVKLH 1670 Score = 50.8 bits (116), Expect = 1e-05 Identities = 38/96 (39%), Positives = 52/96 (54%), Gaps = 12/96 (12%) Query: 231 VSIGSNESNDTVGSLPKSMN-LIDFGGRNPNGSQGSVRVSVLEAFDPLLTEQSNPEYAVG 289 VS S+ N+ S+P+ N LID + + RVSVLEAFDPLL + + + A Sbjct: 316 VSSSSHTGNNGHSSVPRRGNDLIDLNHEDYS------RVSVLEAFDPLLNDNTGNDTA-- 367 Query: 290 SECSSSVYEEYDPLDFLY-GETEMR-ETPVYGTVGK 323 S+S Y EYDP DFLY G+ + P+Y V + Sbjct: 368 -SDSTSYYAEYDPFDFLYSGDAATQYSDPMYEAVNR 402 >U52192-1|AAC47117.1| 1876|Drosophila melanogaster phosphoinositide 3-kinase protein. Length = 1876 Score = 753 bits (1863), Expect = 0.0 Identities = 479/1226 (39%), Positives = 640/1226 (52%), Gaps = 124/1226 (10%) Query: 346 RSTTNKLYDSIVKIRTRNYDSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKYPP 405 R T +LY+ I RT D E F M +VR ++ + D TN GHV+AA Y Sbjct: 502 RKTCTRLYELISDQRTD--DPELLEFYHMVKEVRARYPHDDAPTNVGHVVAAEFNYHYMM 559 Query: 406 NTSIKILVHHAHSD-------------------EPITFTSDVESKVEHVILTVVCSLDED 446 +TSIK++VH A + P+TFT D++S V V+ + SL+ Sbjct: 560 DTSIKVIVHPALNTLQSTVLAASMGKEQVKGYGMPVTFTCDIDSVVAQVVAQALASLEGQ 619 Query: 447 IREDMSGYMLRVRGAKEYLTPGSSLSEYDYIRECVRLEKDVTL--CLHEGRD-STLARTE 503 ++ ++ Y ++ G E+L P S LS+ + + +LEKDV L CL + +ARTE Sbjct: 620 VKGTVTDYAVKPIGLLEWLAPTSRLSQLECVHNSFQLEKDVHLGLCLSTAANMQAIARTE 679 Query: 504 RDDAKDSHLTLDDLFPAQGATPMLSFDNLSILLETLEGEL----SRAIGVTSAEG-SCSP 558 RDD D+ L + L P + ++++DN+ IL+ETLE E+ S A GV SCS Sbjct: 680 RDDEHDADLLPEHLLPNE-VVQIVTYDNMMILIETLEMEIDKLESAADGVPGRSVVSCS- 737 Query: 559 KAVFQAVKAICALAGGVETLHVTHTLNAFAQACTAQG---ANNVVRPEIEREQGAYCSVS 615 V QAVKAICAL G ++T+ + + + C + + PEI + G Y V Sbjct: 738 -GVVQAVKAICALLGSIDTMEIARCVADLKRICEVEQKKYSTGASNPEIVSDYGDYAQVV 796 Query: 616 LAAGSRRDCVSLQGGRVRDAVXXXXXXXXXXXXXDFRLADAHYQAPANPAKAVPAHTISE 675 L S + + ++ +RDAV FR+A + + P +P +S+ Sbjct: 797 LRPRSMLEQIKVKCNELRDAVQELVELYANV----FRVAFS-VKTPDYSTTPIPISCVSK 851 Query: 676 TTLFCIEAVHCLPLCWSHDEYMFHAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWL 735 + CI +H W D+Y QI +GTR L S GG +PR+ F WL Sbjct: 852 PIVVCISCLHRPLPNWKFDDYSLCVQIVYGTRLLSKPNVLTCSNDTSGGLFPRLNFSAWL 911 Query: 736 NLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWA 795 + P+ TLPRE+RL L+G+ Q +E P A+ +G+ ELGW Sbjct: 912 TFDQHPICTLPREARLTFVLYGK-------QAASEGEP----NADQNGERRQVTTELGWC 960 Query: 796 ALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXX-VVNIEIPLYAHTGVK 854 ++QLFDF ++ G Y+L LWP D+ V++IE+P Y ++ Sbjct: 961 SIQLFDFKRVMICGPYLLSLWPPMTDKMLGPAPARGCHPQPDFCPVLSIEVPPYGGR-IE 1019 Query: 855 WTSGEEDKQKNISLKDLPSFD--SLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYL 912 + +E K P +D SLD + Q +LL E G TE REV WEKR YL Sbjct: 1020 FPEHQEVP------KPAPHYDFASLDANLQEELLDTAELG--YTGATERREVFWEKRLYL 1071 Query: 913 VQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKL 972 P ALP VL AA +W + L LL W SPL ++ LLLP +PD VRE A + Sbjct: 1072 QSYPNALPKVLHAAHSWDYANLIDLHALLHSWAPLSPLQSLELLLPRYPDAKVREKAVEW 1131 Query: 973 LNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIP 1032 +++M +D L LPQL Q+L+H+TY +WLLVHSLP+ Sbjct: 1132 ISKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLSKCLESPRFAHHMYWLLVHSLPD-- 1189 Query: 1033 QAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKS 1092 PH ++ E+ T R +MLRAL+ ICGE + + + Q + + Sbjct: 1190 -DPHNSIGAAMVDQEYDESQVTQVRYYR--RNKMMLRALMAICGEKMLQRFMYQHRMCQK 1246 Query: 1093 LCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSN 1152 L +A SVK AKE QPT LPL V + V++C+YF+SN Sbjct: 1247 LTTIAESVKEAKESMRQKSLAAGMDEVHQDLLEQPTCLPLGPELEVTGVSVRNCSYFNSN 1306 Query: 1153 TLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPT 1212 TLPLKINF+G D +PA+FK GDDL+QD L +Q+I+IM+ +WL LDL+MVTF +PT Sbjct: 1307 TLPLKINFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTFNCVPT 1366 Query: 1213 SNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCA 1272 GMIE+V+EAETLR IQ E GLTGSFKD+PIAEWL K NPS LEYQ A NFT SCA Sbjct: 1367 GYKSGMIELVSEAETLRKIQVECGLTGSFKDRPIAEWLGKQNPSPLEYQSAVRNFTLSCA 1426 Query: 1273 GYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTH 1332 GYSVATY+LGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR DR PFVLT Sbjct: 1427 GYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR----DRTPFVLTS 1482 Query: 1333 DMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGSERTVAGGRP 1392 DM YVINGG++P+ F +FV+LCC AFNIVR + D +L A Sbjct: 1483 DMAYVINGGDKPSTDFHYFVDLCCRAFNIVRKNADLLLHTLA------------------ 1524 Query: 1393 QMSLSGVPGVTSAAVSYVRXXXXXXXXXXXXXXXXXRLIHSSLKSNMTQ----------- 1441 M+ +G+PGV S AV YVR ++I SSLKS TQ Sbjct: 1525 HMATAGMPGVNSNAVQYVRRALLPSQSNPEAAATFAKMIQSSLKSWFTQFNFFLHNLAQM 1584 Query: 1442 -------EGRLVSVECLGYEKRYDP----------EKHY------VYALRIYRLGQATPS 1478 G L+S Y + D +KHY +Y L + R GQ P+ Sbjct: 1585 RFTPDEGSGELLSFVPRKYTMQQDGRLKIVKVVCFQKHYSMEKFYMYILEVTRHGQPDPT 1644 Query: 1479 VLYRSYKHFTELYQKICLHFPLAKVH 1504 L+RSY+ FTE +QK+C+HFPL K+H Sbjct: 1645 HLFRSYREFTEFHQKLCMHFPLVKLH 1670 Score = 50.8 bits (116), Expect = 1e-05 Identities = 38/96 (39%), Positives = 52/96 (54%), Gaps = 12/96 (12%) Query: 231 VSIGSNESNDTVGSLPKSMN-LIDFGGRNPNGSQGSVRVSVLEAFDPLLTEQSNPEYAVG 289 VS S+ N+ S+P+ N LID + + RVSVLEAFDPLL + + + A Sbjct: 316 VSSSSHTGNNGHSSVPRRGNDLIDLNHEDYS------RVSVLEAFDPLLNDNTGNDTA-- 367 Query: 290 SECSSSVYEEYDPLDFLY-GETEMR-ETPVYGTVGK 323 S+S Y EYDP DFLY G+ + P+Y V + Sbjct: 368 -SDSTSYYAEYDPFDFLYSGDAATQYSDPMYEAVNR 402 >X92892-1|CAA63485.1| 1876|Drosophila melanogaster phosphoinositide 3-kinase protein. Length = 1876 Score = 751 bits (1857), Expect = 0.0 Identities = 478/1226 (38%), Positives = 639/1226 (52%), Gaps = 124/1226 (10%) Query: 346 RSTTNKLYDSIVKIRTRNYDSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKYPP 405 R T +LY+ I RT D E F M +VR ++ + D TN GHV+AA Y Sbjct: 502 RKTCTRLYELISDQRTD--DPELLEFYHMVKEVRARYPHDDAPTNVGHVVAAEFNYHYMM 559 Query: 406 NTSIKILVHHAHSD-------------------EPITFTSDVESKVEHVILTVVCSLDED 446 +TSIK++VH A + P+TFT D++S V V+ + SL+ Sbjct: 560 DTSIKVIVHPALNTLQSNVLAASMGKEQVKGYGMPVTFTCDIDSVVAQVVAQALASLEGQ 619 Query: 447 IREDMSGYMLRVRGAKEYLTPGSSLSEYDYIRECVRLEKDVTL--CLHEGRD-STLARTE 503 ++ ++ Y ++ G E+L P LS+ + + +LEKDV L CL + +ARTE Sbjct: 620 VKGTVTDYAVKPIGLLEWLAPTLRLSQLECVHNSFQLEKDVHLGLCLSTAANMQAIARTE 679 Query: 504 RDDAKDSHLTLDDLFPAQGATPMLSFDNLSILLETLEGEL----SRAIGVTSAEG-SCSP 558 RDD D+ L + L P + ++++DN+ IL+ETLE E+ S A GV SCS Sbjct: 680 RDDEHDADLLPEHLLPNE-VVQIVTYDNMMILIETLEMEIDKLESAADGVPGRSVVSCS- 737 Query: 559 KAVFQAVKAICALAGGVETLHVTHTLNAFAQACTAQG---ANNVVRPEIEREQGAYCSVS 615 V QAVKAICAL G ++T+ + + + C + + PEI + G Y V Sbjct: 738 -GVVQAVKAICALLGSIDTMEIARCVADLKRICEVEQKKYSTGASNPEIVSDYGDYAQVV 796 Query: 616 LAAGSRRDCVSLQGGRVRDAVXXXXXXXXXXXXXDFRLADAHYQAPANPAKAVPAHTISE 675 L S + + ++ +RDAV FR+A + + P +P +S+ Sbjct: 797 LRPRSMLEQIKVKCNELRDAVQELVELYANV----FRVAFS-VKTPDYSTTPIPISCVSK 851 Query: 676 TTLFCIEAVHCLPLCWSHDEYMFHAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWL 735 + CI +H W D+Y QI +GTR L S GG +PR+ F WL Sbjct: 852 PIVVCISCLHRPLPNWKFDDYSLCVQIVYGTRLLSKPNVLTCSNDTSGGLFPRLNFSAWL 911 Query: 736 NLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWA 795 + P+ TLPRE+RL L+G+ Q +E P A+ +G+ ELGW Sbjct: 912 TFDQHPICTLPREARLTFVLYGK-------QAASEGEP----NADQNGERRQVTTELGWC 960 Query: 796 ALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXX-VVNIEIPLYAHTGVK 854 ++QLFDF ++ G Y+L LWP D+ V++IE+P Y ++ Sbjct: 961 SIQLFDFKRVMICGPYLLSLWPPMTDKMLGPAPARGCHPQPDFCPVLSIEVPPYGGR-IE 1019 Query: 855 WTSGEEDKQKNISLKDLPSFD--SLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYL 912 + +E K P +D SLD + Q +LL E G TE REV WEKR YL Sbjct: 1020 FPEHQEVP------KPAPHYDFASLDANLQEELLDTAELG--YTGATERREVFWEKRLYL 1071 Query: 913 VQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKL 972 P ALP VL AA +W + L LL W SPL ++ LLLP +PD VRE A + Sbjct: 1072 QSYPNALPKVLHAAHSWDYANLIDLHALLHSWAPLSPLQSLELLLPRYPDAKVREKAVEW 1131 Query: 973 LNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIP 1032 +++M +D L LPQL Q+L+H+TY +WLLVHSLP+ Sbjct: 1132 ISKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLSKCLESPRFAHHMYWLLVHSLPD-- 1189 Query: 1033 QAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKS 1092 PH ++ E+ T R +MLRAL+ ICGE + + + Q + + Sbjct: 1190 -DPHNSIGAAMVDQEYDESQVTQVRYYR--RNKMMLRALMAICGEKMLQRFMYQHRMCQK 1246 Query: 1093 LCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSN 1152 L +A SVK AKE QPT LPL V + V++C+YF+SN Sbjct: 1247 LTTIAESVKEAKESMRQKSLAAGMDEVHQDLLEQPTCLPLGPELEVTGVSVRNCSYFNSN 1306 Query: 1153 TLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPT 1212 TLPLKINF+G D +PA+FK GDDL+QD L +Q+I+IM+ +WL LDL+MVTF +PT Sbjct: 1307 TLPLKINFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTFNCVPT 1366 Query: 1213 SNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCA 1272 GMIE+V+EAETLR IQ E GLTGSFKD+PIAEWL K NPS LEYQ A NFT SCA Sbjct: 1367 GYKSGMIELVSEAETLRKIQVECGLTGSFKDRPIAEWLGKQNPSPLEYQSAVRNFTLSCA 1426 Query: 1273 GYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTH 1332 GYSVATY+LGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR DR PFVLT Sbjct: 1427 GYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR----DRTPFVLTS 1482 Query: 1333 DMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGSERTVAGGRP 1392 DM YVINGG++P+ F +FV+LCC AFNIVR + D +L A Sbjct: 1483 DMAYVINGGDKPSTDFHYFVDLCCRAFNIVRKNADLLLHTLA------------------ 1524 Query: 1393 QMSLSGVPGVTSAAVSYVRXXXXXXXXXXXXXXXXXRLIHSSLKSNMTQ----------- 1441 M+ +G+PGV S AV YVR ++I SSLKS TQ Sbjct: 1525 HMATAGMPGVNSNAVQYVRRALLPSQSNPEAAATFAKMIQSSLKSWFTQFNFFLHNLAQM 1584 Query: 1442 -------EGRLVSVECLGYEKRYDP----------EKHY------VYALRIYRLGQATPS 1478 G L+S Y + D +KHY +Y L + R GQ P+ Sbjct: 1585 RFTPDEGSGELLSFVPRKYTMQQDGRLKIVKVVCFQKHYSMEKFYMYILEVTRHGQPDPT 1644 Query: 1479 VLYRSYKHFTELYQKICLHFPLAKVH 1504 L+RSY+ FTE +QK+C+HFPL K+H Sbjct: 1645 HLFRSYREFTEFHQKLCMHFPLVKLH 1670 Score = 49.6 bits (113), Expect = 3e-05 Identities = 38/96 (39%), Positives = 51/96 (53%), Gaps = 12/96 (12%) Query: 231 VSIGSNESNDTVGSLPKSMN-LIDFGGRNPNGSQGSVRVSVLEAFDPLLTEQSNPEYAVG 289 VS S+ N+ S+P N LID + + RVSVLEAFDPLL + + + A Sbjct: 316 VSSSSHTGNNGHSSVPPRGNDLIDLNHEDYS------RVSVLEAFDPLLNDNTGNDTA-- 367 Query: 290 SECSSSVYEEYDPLDFLY-GETEMR-ETPVYGTVGK 323 S+S Y EYDP DFLY G+ + P+Y V + Sbjct: 368 -SDSTSYYAEYDPFDFLYSGDAATQYSDPMYEAVNR 402 >Y09070-1|CAA70291.1| 1088|Drosophila melanogaster phosphoinositide 3-kinase, Dp110 protein. Length = 1088 Score = 202 bits (494), Expect = 2e-51 Identities = 110/237 (46%), Positives = 144/237 (60%), Gaps = 11/237 (4%) Query: 1146 CTYFSSNTLPLKINFIGTD-NAV-IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203 C S PL + F D NA + +FK GDDLRQD L LQ++++MD LW + G+D R Sbjct: 792 CKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFR 851 Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHNPSELEY 1260 M + + S GMIE+V AET+ IQ E G+ T FK + WL +HN + Sbjct: 852 MNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKL 911 Query: 1261 QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRL 1320 +A + FT SCAGY VATY+LG+ DRH+DNIM+K +G LFHIDFG LG + +R Sbjct: 912 NKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRR- 970 Query: 1321 VYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375 +R PFVLTHD VYVIN G +R ++ F HF ELC AF ++R H IL LF++ Sbjct: 971 ---ERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSM 1024 Score = 64.9 bits (151), Expect = 8e-10 Identities = 74/314 (23%), Positives = 129/314 (41%), Gaps = 28/314 (8%) Query: 699 HAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGR 758 H +YHG + L R T + G + +F+ + D+ + LPR +RL + + Sbjct: 371 HVCLYHGDKKLCAQRSTDSPN----GNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEV 426 Query: 759 TQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPT 818 T+ + + N DV Y + L W +FD +L +G + L W Sbjct: 427 TKMSRSKKSSNNKDIALK-------DVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTY 479 Query: 819 SCDRRXXXXXXXXXXXX-----XXXXVVNIEIPLYAHTG-VKWTSGE-------EDKQKN 865 + D + +V++ L + TG V++ S E + +Q N Sbjct: 480 ADDIQSVEVFHPLGTIEPNPRKEECALVDLTF-LSSGTGTVRYPSEEVVLQYAADREQVN 538 Query: 866 ISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLV-QIPGALPLVLL 924 + L + + + + M + R +WE+R ++ ++P L +LL Sbjct: 539 RLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELS-ILL 597 Query: 925 AATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983 W D + LL+ W S ++ LL +PD AVR A + L+ + D+DL Sbjct: 598 HCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLL 657 Query: 984 VLPQLTQALRHETY 997 L QL QA++HE+Y Sbjct: 658 YLLQLVQAIKHESY 671 >DQ792600-2|ABG88076.1| 1088|Drosophila melanogaster PI-3 kinase protein. Length = 1088 Score = 202 bits (494), Expect = 2e-51 Identities = 110/237 (46%), Positives = 144/237 (60%), Gaps = 11/237 (4%) Query: 1146 CTYFSSNTLPLKINFIGTD-NAV-IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203 C S PL + F D NA + +FK GDDLRQD L LQ++++MD LW + G+D R Sbjct: 792 CKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFR 851 Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHNPSELEY 1260 M + + S GMIE+V AET+ IQ E G+ T FK + WL +HN + Sbjct: 852 MNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKL 911 Query: 1261 QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRL 1320 +A + FT SCAGY VATY+LG+ DRH+DNIM+K +G LFHIDFG LG + +R Sbjct: 912 NKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRR- 970 Query: 1321 VYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375 +R PFVLTHD VYVIN G +R ++ F HF ELC AF ++R H IL LF++ Sbjct: 971 ---ERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSM 1024 Score = 64.9 bits (151), Expect = 8e-10 Identities = 74/314 (23%), Positives = 129/314 (41%), Gaps = 28/314 (8%) Query: 699 HAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGR 758 H +YHG + L R T + G + +F+ + D+ + LPR +RL + + Sbjct: 371 HVCLYHGDKKLCAQRSTDSPN----GNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEV 426 Query: 759 TQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPT 818 T+ + + N DV Y + L W +FD +L +G + L W Sbjct: 427 TKMSRSKKSSNNKDIALK-------DVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTY 479 Query: 819 SCDRRXXXXXXXXXXXX-----XXXXVVNIEIPLYAHTG-VKWTSGE-------EDKQKN 865 + D + +V++ L + TG V++ S E + +Q N Sbjct: 480 ADDIQSVEVFHPLGTIEPNPRKEECALVDLTF-LSSGTGTVRYPSEEVVLQYAADREQVN 538 Query: 866 ISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLV-QIPGALPLVLL 924 + L + + + + M + R +WE+R ++ ++P L +LL Sbjct: 539 RLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELS-ILL 597 Query: 925 AATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983 W D + LL+ W S ++ LL +PD AVR A + L+ + D+DL Sbjct: 598 HCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLL 657 Query: 984 VLPQLTQALRHETY 997 L QL QA++HE+Y Sbjct: 658 YLLQLVQAIKHESY 671 >DQ792600-1|ABG88075.1| 1088|Drosophila melanogaster PI-3 kinase protein. Length = 1088 Score = 202 bits (494), Expect = 2e-51 Identities = 110/237 (46%), Positives = 144/237 (60%), Gaps = 11/237 (4%) Query: 1146 CTYFSSNTLPLKINFIGTD-NAV-IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203 C S PL + F D NA + +FK GDDLRQD L LQ++++MD LW + G+D R Sbjct: 792 CKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFR 851 Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHNPSELEY 1260 M + + S GMIE+V AET+ IQ E G+ T FK + WL +HN + Sbjct: 852 MNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKL 911 Query: 1261 QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRL 1320 +A + FT SCAGY VATY+LG+ DRH+DNIM+K +G LFHIDFG LG + +R Sbjct: 912 NKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRR- 970 Query: 1321 VYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375 +R PFVLTHD VYVIN G +R ++ F HF ELC AF ++R H IL LF++ Sbjct: 971 ---ERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSM 1024 Score = 64.9 bits (151), Expect = 8e-10 Identities = 74/314 (23%), Positives = 129/314 (41%), Gaps = 28/314 (8%) Query: 699 HAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGR 758 H +YHG + L R T + G + +F+ + D+ + LPR +RL + + Sbjct: 371 HVCLYHGDKKLCAQRSTDSPN----GNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEV 426 Query: 759 TQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPT 818 T+ + + N DV Y + L W +FD +L +G + L W Sbjct: 427 TKMSRSKKSSNNKDIALK-------DVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTY 479 Query: 819 SCDRRXXXXXXXXXXXX-----XXXXVVNIEIPLYAHTG-VKWTSGE-------EDKQKN 865 + D + +V++ L + TG V++ S E + +Q N Sbjct: 480 ADDIQSVEVFHPLGTIEPNPRKEECALVDLTF-LSSGTGTVRYPSEEVVLQYAADREQVN 538 Query: 866 ISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLV-QIPGALPLVLL 924 + L + + + + M + R +WE+R ++ ++P L +LL Sbjct: 539 RLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELS-ILL 597 Query: 925 AATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983 W D + LL+ W S ++ LL +PD AVR A + L+ + D+DL Sbjct: 598 HCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLL 657 Query: 984 VLPQLTQALRHETY 997 L QL QA++HE+Y Sbjct: 658 YLLQLVQAIKHESY 671 >DQ792599-2|ABG88074.1| 1088|Drosophila melanogaster PI-3 kinase protein. Length = 1088 Score = 202 bits (494), Expect = 2e-51 Identities = 110/237 (46%), Positives = 144/237 (60%), Gaps = 11/237 (4%) Query: 1146 CTYFSSNTLPLKINFIGTD-NAV-IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203 C S PL + F D NA + +FK GDDLRQD L LQ++++MD LW + G+D R Sbjct: 792 CKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFR 851 Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHNPSELEY 1260 M + + S GMIE+V AET+ IQ E G+ T FK + WL +HN + Sbjct: 852 MNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKL 911 Query: 1261 QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRL 1320 +A + FT SCAGY VATY+LG+ DRH+DNIM+K +G LFHIDFG LG + +R Sbjct: 912 NKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRR- 970 Query: 1321 VYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375 +R PFVLTHD VYVIN G +R ++ F HF ELC AF ++R H IL LF++ Sbjct: 971 ---ERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSM 1024 Score = 64.9 bits (151), Expect = 8e-10 Identities = 74/314 (23%), Positives = 129/314 (41%), Gaps = 28/314 (8%) Query: 699 HAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGR 758 H +YHG + L R T + G + +F+ + D+ + LPR +RL + + Sbjct: 371 HVCLYHGDKKLCAQRSTDSPN----GNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEV 426 Query: 759 TQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPT 818 T+ + + N DV Y + L W +FD +L +G + L W Sbjct: 427 TKMSRSKKSSNNKDIALK-------DVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTY 479 Query: 819 SCDRRXXXXXXXXXXXX-----XXXXVVNIEIPLYAHTG-VKWTSGE-------EDKQKN 865 + D + +V++ L + TG V++ S E + +Q N Sbjct: 480 ADDIQSVEVFHPLGTIEPNPRKEECALVDLTF-LSSGTGTVRYPSEEVVLQYAADREQVN 538 Query: 866 ISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLV-QIPGALPLVLL 924 + L + + + + M + R +WE+R ++ ++P L +LL Sbjct: 539 RLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELS-ILL 597 Query: 925 AATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983 W D + LL+ W S ++ LL +PD AVR A + L+ + D+DL Sbjct: 598 HCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLL 657 Query: 984 VLPQLTQALRHETY 997 L QL QA++HE+Y Sbjct: 658 YLLQLVQAIKHESY 671 >DQ792599-1|ABG88073.1| 1088|Drosophila melanogaster PI-3 kinase protein. Length = 1088 Score = 202 bits (494), Expect = 2e-51 Identities = 110/237 (46%), Positives = 144/237 (60%), Gaps = 11/237 (4%) Query: 1146 CTYFSSNTLPLKINFIGTD-NAV-IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203 C S PL + F D NA + +FK GDDLRQD L LQ++++MD LW + G+D R Sbjct: 792 CKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFR 851 Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHNPSELEY 1260 M + + S GMIE+V AET+ IQ E G+ T FK + WL +HN + Sbjct: 852 MNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKL 911 Query: 1261 QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRL 1320 +A + FT SCAGY VATY+LG+ DRH+DNIM+K +G LFHIDFG LG + +R Sbjct: 912 NKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRR- 970 Query: 1321 VYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375 +R PFVLTHD VYVIN G +R ++ F HF ELC AF ++R H IL LF++ Sbjct: 971 ---ERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSM 1024 Score = 64.9 bits (151), Expect = 8e-10 Identities = 74/314 (23%), Positives = 129/314 (41%), Gaps = 28/314 (8%) Query: 699 HAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGR 758 H +YHG + L R T + G + +F+ + D+ + LPR +RL + + Sbjct: 371 HVCLYHGDKKLCAQRSTDSPN----GNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEV 426 Query: 759 TQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPT 818 T+ + + N DV Y + L W +FD +L +G + L W Sbjct: 427 TKMSRSKKSSNNKDIALK-------DVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTY 479 Query: 819 SCDRRXXXXXXXXXXXX-----XXXXVVNIEIPLYAHTG-VKWTSGE-------EDKQKN 865 + D + +V++ L + TG V++ S E + +Q N Sbjct: 480 ADDIQSVEVFHPLGTIEPNPRKEECALVDLTF-LSSGTGTVRYPSEEVVLQYAADREQVN 538 Query: 866 ISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLV-QIPGALPLVLL 924 + L + + + + M + R +WE+R ++ ++P L +LL Sbjct: 539 RLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELS-ILL 597 Query: 925 AATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983 W D + LL+ W S ++ LL +PD AVR A + L+ + D+DL Sbjct: 598 HCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLL 657 Query: 984 VLPQLTQALRHETY 997 L QL QA++HE+Y Sbjct: 658 YLLQLVQAIKHESY 671 >BT003173-1|AAO24928.1| 1088|Drosophila melanogaster SD05105p protein. Length = 1088 Score = 202 bits (494), Expect = 2e-51 Identities = 110/237 (46%), Positives = 144/237 (60%), Gaps = 11/237 (4%) Query: 1146 CTYFSSNTLPLKINFIGTD-NAV-IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203 C S PL + F D NA + +FK GDDLRQD L LQ++++MD LW + G+D R Sbjct: 792 CKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFR 851 Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHNPSELEY 1260 M + + S GMIE+V AET+ IQ E G+ T FK + WL +HN + Sbjct: 852 MNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKL 911 Query: 1261 QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRL 1320 +A + FT SCAGY VATY+LG+ DRH+DNIM+K +G LFHIDFG LG + +R Sbjct: 912 NKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRR- 970 Query: 1321 VYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375 +R PFVLTHD VYVIN G +R ++ F HF ELC AF ++R H IL LF++ Sbjct: 971 ---ERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSM 1024 Score = 64.9 bits (151), Expect = 8e-10 Identities = 74/314 (23%), Positives = 129/314 (41%), Gaps = 28/314 (8%) Query: 699 HAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGR 758 H +YHG + L R T + G + +F+ + D+ + LPR +RL + + Sbjct: 371 HVCLYHGDKKLCAQRSTDSPN----GNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEV 426 Query: 759 TQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPT 818 T+ + + N DV Y + L W +FD +L +G + L W Sbjct: 427 TKMSRSKKSSNNKDIALK-------DVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTY 479 Query: 819 SCDRRXXXXXXXXXXXX-----XXXXVVNIEIPLYAHTG-VKWTSGE-------EDKQKN 865 + D + +V++ L + TG V++ S E + +Q N Sbjct: 480 ADDIQSVEVFHPLGTIEPNPRKEECALVDLTF-LSSGTGTVRYPSEEVVLQYAADREQVN 538 Query: 866 ISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLV-QIPGALPLVLL 924 + L + + + + M + R +WE+R ++ ++P L +LL Sbjct: 539 RLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELS-ILL 597 Query: 925 AATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983 W D + LL+ W S ++ LL +PD AVR A + L+ + D+DL Sbjct: 598 HCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLL 657 Query: 984 VLPQLTQALRHETY 997 L QL QA++HE+Y Sbjct: 658 YLLQLVQAIKHESY 671 >AE014297-2834|AAN14359.1| 1088|Drosophila melanogaster CG4141-PB, isoform B protein. Length = 1088 Score = 202 bits (494), Expect = 2e-51 Identities = 110/237 (46%), Positives = 144/237 (60%), Gaps = 11/237 (4%) Query: 1146 CTYFSSNTLPLKINFIGTD-NAV-IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203 C S PL + F D NA + +FK GDDLRQD L LQ++++MD LW + G+D R Sbjct: 792 CKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFR 851 Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHNPSELEY 1260 M + + S GMIE+V AET+ IQ E G+ T FK + WL +HN + Sbjct: 852 MNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKL 911 Query: 1261 QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRL 1320 +A + FT SCAGY VATY+LG+ DRH+DNIM+K +G LFHIDFG LG + +R Sbjct: 912 NKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRR- 970 Query: 1321 VYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375 +R PFVLTHD VYVIN G +R ++ F HF ELC AF ++R H IL LF++ Sbjct: 971 ---ERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSM 1024 Score = 64.9 bits (151), Expect = 8e-10 Identities = 74/314 (23%), Positives = 129/314 (41%), Gaps = 28/314 (8%) Query: 699 HAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGR 758 H +YHG + L R T + G + +F+ + D+ + LPR +RL + + Sbjct: 371 HVCLYHGDKKLCAQRSTDSPN----GNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEV 426 Query: 759 TQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPT 818 T+ + + N DV Y + L W +FD +L +G + L W Sbjct: 427 TKMSRSKKSSNNKDIALK-------DVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTY 479 Query: 819 SCDRRXXXXXXXXXXXX-----XXXXVVNIEIPLYAHTG-VKWTSGE-------EDKQKN 865 + D + +V++ L + TG V++ S E + +Q N Sbjct: 480 ADDIQSVEVFHPLGTIEPNPRKEECALVDLTF-LSSGTGTVRYPSEEVVLQYAADREQVN 538 Query: 866 ISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLV-QIPGALPLVLL 924 + L + + + + M + R +WE+R ++ ++P L +LL Sbjct: 539 RLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELS-ILL 597 Query: 925 AATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983 W D + LL+ W S ++ LL +PD AVR A + L+ + D+DL Sbjct: 598 HCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLL 657 Query: 984 VLPQLTQALRHETY 997 L QL QA++HE+Y Sbjct: 658 YLLQLVQAIKHESY 671 >AE014297-2833|AAF55792.1| 1088|Drosophila melanogaster CG4141-PA, isoform A protein. Length = 1088 Score = 202 bits (494), Expect = 2e-51 Identities = 110/237 (46%), Positives = 144/237 (60%), Gaps = 11/237 (4%) Query: 1146 CTYFSSNTLPLKINFIGTD-NAV-IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203 C S PL + F D NA + +FK GDDLRQD L LQ++++MD LW + G+D R Sbjct: 792 CKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFR 851 Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHNPSELEY 1260 M + + S GMIE+V AET+ IQ E G+ T FK + WL +HN + Sbjct: 852 MNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKL 911 Query: 1261 QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRL 1320 +A + FT SCAGY VATY+LG+ DRH+DNIM+K +G LFHIDFG LG + +R Sbjct: 912 NKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRR- 970 Query: 1321 VYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375 +R PFVLTHD VYVIN G +R ++ F HF ELC AF ++R H IL LF++ Sbjct: 971 ---ERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSM 1024 Score = 64.9 bits (151), Expect = 8e-10 Identities = 74/314 (23%), Positives = 129/314 (41%), Gaps = 28/314 (8%) Query: 699 HAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGR 758 H +YHG + L R T + G + +F+ + D+ + LPR +RL + + Sbjct: 371 HVCLYHGDKKLCAQRSTDSPN----GNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEV 426 Query: 759 TQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPT 818 T+ + + N DV Y + L W +FD +L +G + L W Sbjct: 427 TKMSRSKKSSNNKDIALK-------DVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTY 479 Query: 819 SCDRRXXXXXXXXXXXX-----XXXXVVNIEIPLYAHTG-VKWTSGE-------EDKQKN 865 + D + +V++ L + TG V++ S E + +Q N Sbjct: 480 ADDIQSVEVFHPLGTIEPNPRKEECALVDLTF-LSSGTGTVRYPSEEVVLQYAADREQVN 538 Query: 866 ISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLV-QIPGALPLVLL 924 + L + + + + M + R +WE+R ++ ++P L +LL Sbjct: 539 RLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELS-ILL 597 Query: 925 AATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983 W D + LL+ W S ++ LL +PD AVR A + L+ + D+DL Sbjct: 598 HCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLL 657 Query: 984 VLPQLTQALRHETY 997 L QL QA++HE+Y Sbjct: 658 YLLQLVQAIKHESY 671 >AY113648-1|AAM29653.1| 1308|Drosophila melanogaster SD12145p protein. Length = 1308 Score = 129 bits (311), Expect = 3e-29 Identities = 83/208 (39%), Positives = 117/208 (56%), Gaps = 16/208 (7%) Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229 A+FKVGDD+RQD L LQVI I ++ + GLDL + ++ + T+ G+IE V A++ Sbjct: 1053 AIFKVGDDVRQDMLALQVITIFKNIFQQVGLDLFLFPYRVVATAPGCGVIECVPNAKSRD 1112 Query: 1230 AI--QTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287 + QT+ GL+ F+ + E S E+Q AR NF S A YS+ YLL I DRH Sbjct: 1113 QLGRQTDSGLSEYFQHQYGDE-------SSKEFQAARANFVKSMAAYSLIGYLLQIKDRH 1165 Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347 N NIM+ GH+ HIDFG F+ ++ GN I P + D + +I GG+ + Sbjct: 1166 NGNIMIDKDGHIIHIDFG-FMFESSPGGN------IGFEPDMKLTDEMVMIMGGKMDSPA 1218 Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375 F+ F ELC AF VR + D I+ L +L Sbjct: 1219 FKWFCELCVQAFLAVRPYQDAIVSLVSL 1246 Score = 31.5 bits (68), Expect = 9.3 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 944 WEKPSPLNAMHLLLPCFPDVAVR-ETAAKLLNEMSDDDLCRVLPQLTQALRHET 996 W +P+ A+ +P + + A K L+ + + +PQL QALRH+T Sbjct: 819 WSPVTPIQALAYFSRQYPSHPLTAQYAVKTLSSYPAESVLPYIPQLVQALRHDT 872 >AL121804-6|CAB65858.1| 2160|Drosophila melanogaster EG:BACR7C10.2 protein. Length = 2160 Score = 129 bits (311), Expect = 3e-29 Identities = 83/208 (39%), Positives = 117/208 (56%), Gaps = 16/208 (7%) Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229 A+FKVGDD+RQD L LQVI I ++ + GLDL + ++ + T+ G+IE V A++ Sbjct: 1905 AIFKVGDDVRQDMLALQVITIFKNIFQQVGLDLFLFPYRVVATAPGCGVIECVPNAKSRD 1964 Query: 1230 AI--QTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287 + QT+ GL+ F+ + E S E+Q AR NF S A YS+ YLL I DRH Sbjct: 1965 QLGRQTDSGLSEYFQHQYGDE-------SSKEFQAARANFVKSMAAYSLIGYLLQIKDRH 2017 Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347 N NIM+ GH+ HIDFG F+ ++ GN I P + D + +I GG+ + Sbjct: 2018 NGNIMIDKDGHIIHIDFG-FMFESSPGGN------IGFEPDMKLTDEMVMIMGGKMDSPA 2070 Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375 F+ F ELC AF VR + D I+ L +L Sbjct: 2071 FKWFCELCVQAFLAVRPYQDAIVSLVSL 2098 Score = 31.5 bits (68), Expect = 9.3 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 944 WEKPSPLNAMHLLLPCFPDVAVR-ETAAKLLNEMSDDDLCRVLPQLTQALRHET 996 W +P+ A+ +P + + A K L+ + + +PQL QALRH+T Sbjct: 1671 WSPVTPIQALAYFSRQYPSHPLTAQYAVKTLSSYPAESVLPYIPQLVQALRHDT 1724 >AE014298-425|AAF45800.2| 2178|Drosophila melanogaster CG10260-PB protein. Length = 2178 Score = 129 bits (311), Expect = 3e-29 Identities = 83/208 (39%), Positives = 117/208 (56%), Gaps = 16/208 (7%) Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229 A+FKVGDD+RQD L LQVI I ++ + GLDL + ++ + T+ G+IE V A++ Sbjct: 1923 AIFKVGDDVRQDMLALQVITIFKNIFQQVGLDLFLFPYRVVATAPGCGVIECVPNAKSRD 1982 Query: 1230 AI--QTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287 + QT+ GL+ F+ + E S E+Q AR NF S A YS+ YLL I DRH Sbjct: 1983 QLGRQTDSGLSEYFQHQYGDE-------SSKEFQAARANFVKSMAAYSLIGYLLQIKDRH 2035 Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347 N NIM+ GH+ HIDFG F+ ++ GN I P + D + +I GG+ + Sbjct: 2036 NGNIMIDKDGHIIHIDFG-FMFESSPGGN------IGFEPDMKLTDEMVMIMGGKMDSPA 2088 Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375 F+ F ELC AF VR + D I+ L +L Sbjct: 2089 FKWFCELCVQAFLAVRPYQDAIVSLVSL 2116 Score = 31.5 bits (68), Expect = 9.3 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 944 WEKPSPLNAMHLLLPCFPDVAVR-ETAAKLLNEMSDDDLCRVLPQLTQALRHET 996 W +P+ A+ +P + + A K L+ + + +PQL QALRH+T Sbjct: 1689 WSPVTPIQALAYFSRQYPSHPLTAQYAVKTLSSYPAESVLPYIPQLVQALRHDT 1742 >X99912-1|CAA68185.1| 949|Drosophila melanogaster 1-phosphatidylinositol 3-kinase protein. Length = 949 Score = 124 bits (299), Expect = 1e-27 Identities = 81/251 (32%), Positives = 127/251 (50%), Gaps = 17/251 (6%) Query: 1126 QPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGT-DNAVIPAMFKVGDDLRQDALV 1184 +P PL Y+ + + F S +P K+ F+ + + A+FK GDDLRQD L+ Sbjct: 650 EPIPFPLDPEIYITKIVPMRTSLFKSALMPAKLTFVTSIAHHEYAAIFKHGDDLRQDQLI 709 Query: 1185 LQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDK 1244 LQ+I +MD L + LDL++ ++ L TS+ G ++ V + E + F+ Sbjct: 710 LQMITLMDKLLRRENLDLKLTPYKVLATSSKHGFLQYVDSCTVAEVLAREGNIHNFFRKH 769 Query: 1245 PIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDF 1304 + + P + + D + SCAGY V TYLLG+ DRH DN++L T+G LFHIDF Sbjct: 770 HPCD----NGPYGISAE-VMDTYIKSCAGYCVITYLLGVGDRHLDNLLLTTNGKLFHIDF 824 Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRA 1364 G LG K + P L+ +MV + G ++ F + C A+ +R Sbjct: 825 GYILGRDP-----KPMP----PPMKLSKEMVEAMGGIS--SEHHHEFRKQCYTAYLHLRR 873 Query: 1365 HHDHILDLFAL 1375 H + +L+LF+L Sbjct: 874 HANVMLNLFSL 884 Score = 48.4 bits (110), Expect = 8e-05 Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Query: 897 MPTECREVMWEKRQYLVQIPGALPLVLLAATNW-YGDHREQLIGLLRLWEKPSPLNAMHL 955 + +E ++++W+ R YL AL L NW D Q + +L W +A+ L Sbjct: 310 LSSEEQDLLWKFRFYLSSHKKALTK-FLKCINWKLEDEVTQALWMLANWAPMDVEDALEL 368 Query: 956 LLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995 L P F VR+ A L + D+DL L QL QAL++E Sbjct: 369 LSPTFTHPQVRKYAVSRLAQAPDEDLLLYLLQLVQALKYE 408 >AY058362-1|AAL13591.1| 949|Drosophila melanogaster GH13170p protein. Length = 949 Score = 124 bits (299), Expect = 1e-27 Identities = 81/251 (32%), Positives = 127/251 (50%), Gaps = 17/251 (6%) Query: 1126 QPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGT-DNAVIPAMFKVGDDLRQDALV 1184 +P PL Y+ + + F S +P K+ F+ + + A+FK GDDLRQD L+ Sbjct: 650 EPIPFPLDPEIYITKIVPMRTSLFKSALMPAKLTFVTSIAHHEYAAIFKHGDDLRQDQLI 709 Query: 1185 LQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDK 1244 LQ+I +MD L + LDL++ ++ L TS+ G ++ V + E + F+ Sbjct: 710 LQMITLMDKLLRRENLDLKLTPYKVLATSSKHGFLQYVDSCTVAEVLAREGNIHNFFRKH 769 Query: 1245 PIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDF 1304 + + P + + D + SCAGY V TYLLG+ DRH DN++L T+G LFHIDF Sbjct: 770 HPCD----NGPYGISAE-VMDTYIKSCAGYCVITYLLGVGDRHLDNLLLTTNGKLFHIDF 824 Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRA 1364 G LG K + P L+ +MV + G ++ F + C A+ +R Sbjct: 825 GYILGRDP-----KPMP----PPMKLSKEMVEAMGGIS--SEHHHEFRKQCYTAYLHLRR 873 Query: 1365 HHDHILDLFAL 1375 H + +L+LF+L Sbjct: 874 HANVMLNLFSL 884 Score = 48.0 bits (109), Expect = 1e-04 Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Query: 897 MPTECREVMWEKRQYLVQIPGALPLVLLAATNW-YGDHREQLIGLLRLWEKPSPLNAMHL 955 + +E ++++W+ R YL AL L NW D Q + +L W +A+ L Sbjct: 310 LSSEEQDLVWKFRFYLSSHKKALTK-FLKCINWKLEDEVTQALWMLANWAPMDVEDALEL 368 Query: 956 LLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995 L P F VR+ A L + D+DL L QL QAL++E Sbjct: 369 LSPTFTHPQVRKYAVSRLAQAPDEDLLLYLLQLVQALKYE 408 >AE013599-3631|AAF47030.2| 949|Drosophila melanogaster CG5373-PA protein. Length = 949 Score = 124 bits (299), Expect = 1e-27 Identities = 81/251 (32%), Positives = 127/251 (50%), Gaps = 17/251 (6%) Query: 1126 QPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGT-DNAVIPAMFKVGDDLRQDALV 1184 +P PL Y+ + + F S +P K+ F+ + + A+FK GDDLRQD L+ Sbjct: 650 EPIPFPLDPEIYITKIVPMRTSLFKSALMPAKLTFVTSIAHHEYAAIFKHGDDLRQDQLI 709 Query: 1185 LQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDK 1244 LQ+I +MD L + LDL++ ++ L TS+ G ++ V + E + F+ Sbjct: 710 LQMITLMDKLLRRENLDLKLTPYKVLATSSKHGFLQYVDSCTVAEVLAREGNIHNFFRKH 769 Query: 1245 PIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDF 1304 + + P + + D + SCAGY V TYLLG+ DRH DN++L T+G LFHIDF Sbjct: 770 HPCD----NGPYGISAE-VMDTYIKSCAGYCVITYLLGVGDRHLDNLLLTTNGKLFHIDF 824 Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRA 1364 G LG K + P L+ +MV + G ++ F + C A+ +R Sbjct: 825 GYILGRDP-----KPMP----PPMKLSKEMVEAMGGIS--SEHHHEFRKQCYTAYLHLRR 873 Query: 1365 HHDHILDLFAL 1375 H + +L+LF+L Sbjct: 874 HANVMLNLFSL 884 Score = 48.0 bits (109), Expect = 1e-04 Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Query: 897 MPTECREVMWEKRQYLVQIPGALPLVLLAATNW-YGDHREQLIGLLRLWEKPSPLNAMHL 955 + +E ++++W+ R YL AL L NW D Q + +L W +A+ L Sbjct: 310 LSSEEQDLVWKFRFYLSSHKKALTK-FLKCINWKLEDEVTQALWMLANWAPMDVEDALEL 368 Query: 956 LLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995 L P F VR+ A L + D+DL L QL QAL++E Sbjct: 369 LSPTFTHPQVRKYAVSRLAQAPDEDLLLYLLQLVQALKYE 408 >AY052049-1|AAK93473.1| 1674|Drosophila melanogaster LP07057p protein. Length = 1674 Score = 107 bits (258), Expect = 9e-23 Identities = 65/205 (31%), Positives = 112/205 (54%), Gaps = 13/205 (6%) Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226 ++ A+ K GDDLRQ+ + Q++++ +W + +DL + ++ + SN G+IE + Sbjct: 1414 LLSAIVKCGDDLRQELMATQLLQMFKIIWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTV 1473 Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286 +L I+ S K+ I E+ +PS ++RA+ NF SCA Y + +YLL + DR Sbjct: 1474 SLHQIKKN--SNKSLKEYFIDEY---GSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDR 1528 Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346 HN NI+ + GH+ HIDFG L + K L + +++PF LT + V V+ G ++ Sbjct: 1529 HNGNILFHSDGHIIHIDFGFILSISP-----KNLGF-EQSPFKLTPEFVEVMGG--TSSE 1580 Query: 1347 RFQHFVELCCMAFNIVRAHHDHILD 1371 ++ F +L + R H D I++ Sbjct: 1581 HWREFNKLLLVGMMSARKHMDRIIN 1605 >AF242375-1|AAK27793.2| 1338|Drosophila melanogaster phosphatidylinositol 4-kinasebeta isoform protein. Length = 1338 Score = 107 bits (258), Expect = 9e-23 Identities = 65/205 (31%), Positives = 112/205 (54%), Gaps = 13/205 (6%) Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226 ++ A+ K GDDLRQ+ + Q++++ +W + +DL + ++ + SN G+IE + Sbjct: 1078 LLSAIVKCGDDLRQELMATQLLQMFKIIWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTV 1137 Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286 +L I+ S K+ I E+ +PS ++RA+ NF SCA Y + +YLL + DR Sbjct: 1138 SLHQIKKN--SNKSLKEYFIDEY---GSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDR 1192 Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346 HN NI+ + GH+ HIDFG L + K L + +++PF LT + V V+ G ++ Sbjct: 1193 HNGNILFHSDGHIIHIDFGFILSISP-----KNLGF-EQSPFKLTPEFVEVMGG--TSSE 1244 Query: 1347 RFQHFVELCCMAFNIVRAHHDHILD 1371 ++ F +L + R H D I++ Sbjct: 1245 HWREFNKLLLVGMMSARKHMDRIIN 1269 >AE014296-82|AAN11438.1| 1338|Drosophila melanogaster CG7004-PC, isoform C protein. Length = 1338 Score = 107 bits (258), Expect = 9e-23 Identities = 65/205 (31%), Positives = 112/205 (54%), Gaps = 13/205 (6%) Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226 ++ A+ K GDDLRQ+ + Q++++ +W + +DL + ++ + SN G+IE + Sbjct: 1078 LLSAIVKCGDDLRQELMATQLLQMFKIIWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTV 1137 Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286 +L I+ S K+ I E+ +PS ++RA+ NF SCA Y + +YLL + DR Sbjct: 1138 SLHQIKKN--SNKSLKEYFIDEY---GSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDR 1192 Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346 HN NI+ + GH+ HIDFG L + K L + +++PF LT + V V+ G ++ Sbjct: 1193 HNGNILFHSDGHIIHIDFGFILSISP-----KNLGF-EQSPFKLTPEFVEVMGG--TSSE 1244 Query: 1347 RFQHFVELCCMAFNIVRAHHDHILD 1371 ++ F +L + R H D I++ Sbjct: 1245 HWREFNKLLLVGMMSARKHMDRIIN 1269 >AE014296-81|AAN11437.1| 1674|Drosophila melanogaster CG7004-PB, isoform B protein. Length = 1674 Score = 107 bits (258), Expect = 9e-23 Identities = 65/205 (31%), Positives = 112/205 (54%), Gaps = 13/205 (6%) Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226 ++ A+ K GDDLRQ+ + Q++++ +W + +DL + ++ + SN G+IE + Sbjct: 1414 LLSAIVKCGDDLRQELMATQLLQMFKIIWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTV 1473 Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286 +L I+ S K+ I E+ +PS ++RA+ NF SCA Y + +YLL + DR Sbjct: 1474 SLHQIKKN--SNKSLKEYFIDEY---GSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDR 1528 Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346 HN NI+ + GH+ HIDFG L + K L + +++PF LT + V V+ G ++ Sbjct: 1529 HNGNILFHSDGHIIHIDFGFILSISP-----KNLGF-EQSPFKLTPEFVEVMGG--TSSE 1580 Query: 1347 RFQHFVELCCMAFNIVRAHHDHILD 1371 ++ F +L + R H D I++ Sbjct: 1581 HWREFNKLLLVGMMSARKHMDRIIN 1605 >AE014296-80|AAF47375.2| 1674|Drosophila melanogaster CG7004-PA, isoform A protein. Length = 1674 Score = 107 bits (258), Expect = 9e-23 Identities = 65/205 (31%), Positives = 112/205 (54%), Gaps = 13/205 (6%) Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226 ++ A+ K GDDLRQ+ + Q++++ +W + +DL + ++ + SN G+IE + Sbjct: 1414 LLSAIVKCGDDLRQELMATQLLQMFKIIWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTV 1473 Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286 +L I+ S K+ I E+ +PS ++RA+ NF SCA Y + +YLL + DR Sbjct: 1474 SLHQIKKN--SNKSLKEYFIDEY---GSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDR 1528 Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346 HN NI+ + GH+ HIDFG L + K L + +++PF LT + V V+ G ++ Sbjct: 1529 HNGNILFHSDGHIIHIDFGFILSISP-----KNLGF-EQSPFKLTPEFVEVMGG--TSSE 1580 Query: 1347 RFQHFVELCCMAFNIVRAHHDHILD 1371 ++ F +L + R H D I++ Sbjct: 1581 HWREFNKLLLVGMMSARKHMDRIIN 1605 >AY069275-1|AAL39420.1| 455|Drosophila melanogaster GM10438p protein. Length = 455 Score = 53.2 bits (122), Expect = 3e-06 Identities = 29/58 (50%), Positives = 39/58 (67%), Gaps = 3/58 (5%) Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFG 1305 WL K SEL ++R R+N+T S A S+ Y+LG+ DRH N+ML + SG + HIDFG Sbjct: 210 WL-KSPSSELWFER-RNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFG 265 Score = 35.1 bits (77), Expect = 0.76 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWL----KAGLDLRMV 1205 +S P K+ G++ + K +DLRQD V+Q+ +++TL L +L + Sbjct: 70 TSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQ 129 Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAI 1231 + +P S + G+I V +TL + Sbjct: 130 RYAVIPLSTNSGLIGWVPHCDTLHTL 155 >AY052068-1|AAK93492.1| 760|Drosophila melanogaster SD02269p protein. Length = 760 Score = 53.2 bits (122), Expect = 3e-06 Identities = 29/58 (50%), Positives = 39/58 (67%), Gaps = 3/58 (5%) Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFG 1305 WL K SEL ++R R+N+T S A S+ Y+LG+ DRH N+ML + SG + HIDFG Sbjct: 515 WL-KSPSSELWFER-RNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFG 570 Score = 35.1 bits (77), Expect = 0.76 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWL----KAGLDLRMV 1205 +S P K+ G++ + K +DLRQD V+Q+ +++TL L +L + Sbjct: 375 TSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQ 434 Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAI 1231 + +P S + G+I V +TL + Sbjct: 435 RYAVIPLSTNSGLIGWVPHCDTLHTL 460 >AE014134-2272|AAF53237.1| 2470|Drosophila melanogaster CG5092-PA protein. Length = 2470 Score = 53.2 bits (122), Expect = 3e-06 Identities = 29/58 (50%), Positives = 39/58 (67%), Gaps = 3/58 (5%) Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFG 1305 WL K SEL ++R R+N+T S A S+ Y+LG+ DRH N+ML + SG + HIDFG Sbjct: 2225 WL-KSPSSELWFER-RNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFG 2280 Score = 35.1 bits (77), Expect = 0.76 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWL----KAGLDLRMV 1205 +S P K+ G++ + K +DLRQD V+Q+ +++TL L +L + Sbjct: 2085 TSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQ 2144 Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAI 1231 + +P S + G+I V +TL + Sbjct: 2145 RYAVIPLSTNSGLIGWVPHCDTLHTL 2170 >U34925-2|AAC46881.1| 2354|Drosophila melanogaster MEI-41 protein. Length = 2354 Score = 50.4 bits (115), Expect = 2e-05 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 7/89 (7%) Query: 1248 EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGK 1306 EWL + + + AR+ + + A S+ Y+LG+ DRH +NI+ + +G H+DF Sbjct: 2163 EWLRQRFATPHSWYEARNTYIRTVAVMSMVGYILGLGDRHGENILFAEGNGDAVHVDFN- 2221 Query: 1307 FLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335 +F + L Y + PF LTH+M+ Sbjct: 2222 -----CLFNQGELLPYPEVVPFRLTHNMI 2245 >AY282465-1|AAQ22732.1| 2517|Drosophila melanogaster Mei-41 protein. Length = 2517 Score = 50.4 bits (115), Expect = 2e-05 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 7/89 (7%) Query: 1248 EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGK 1306 EWL + + + AR+ + + A S+ Y+LG+ DRH +NI+ + +G H+DF Sbjct: 2326 EWLRQRFATPHSWYEARNTYIRTVAVMSMVGYILGLGDRHGENILFAEGNGDAVHVDFN- 2384 Query: 1307 FLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335 +F + L Y + PF LTH+M+ Sbjct: 2385 -----CLFNQGELLPYPEVVPFRLTHNMI 2408 >AE014298-2397|AAF48604.2| 2517|Drosophila melanogaster CG4252-PA protein. Length = 2517 Score = 50.4 bits (115), Expect = 2e-05 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 7/89 (7%) Query: 1248 EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGK 1306 EWL + + + AR+ + + A S+ Y+LG+ DRH +NI+ + +G H+DF Sbjct: 2326 EWLRQRFATPHSWYEARNTYIRTVAVMSMVGYILGLGDRHGENILFAEGNGDAVHVDFN- 2384 Query: 1307 FLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335 +F + L Y + PF LTH+M+ Sbjct: 2385 -----CLFNQGELLPYPEVVPFRLTHNMI 2408 >BT011117-1|AAR82784.1| 1157|Drosophila melanogaster LD17186p protein. Length = 1157 Score = 37.5 bits (83), Expect = 0.14 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 9/89 (10%) Query: 1259 EYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGHLFHIDFGKFLGDAQMFGNF 1317 E++++ F + S+ Y++G+ DRH DN+++ SG + HID+ F Sbjct: 17 EWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYN------VCFEKG 70 Query: 1318 KRLVYIDRAPFVLTHDMVYV--INGGERP 1344 + L ++ PF LT ++V I G E P Sbjct: 71 RTLRIPEKVPFRLTQNLVQAMGITGIEGP 99 >AY395750-1|AAR89513.1| 1199|Drosophila melanogaster ATM protein protein. Length = 1199 Score = 37.5 bits (83), Expect = 0.14 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 7/70 (10%) Query: 1267 FTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDR 1325 +T S A S+ Y+LG+ DRH NI++ + + + HIDFG F K + Sbjct: 1018 YTNSVATTSMVGYVLGLGDRHTQNILVDQQTAEVIHIDFG------IAFEQGKIQTTPET 1071 Query: 1326 APFVLTHDMV 1335 PF LT D V Sbjct: 1072 VPFRLTRDFV 1081 Score = 36.3 bits (80), Expect = 0.33 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 4/75 (5%) Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAG----LDLRMVTFQAL 1210 P+KI + +D + + K DDLRQDA++ QV I++ L + L++ T++ Sbjct: 864 PVKIMCVCSDGKIRAQLVKGKDDLRQDAVMQQVFGIVNELLNQDSEFIERKLKLRTYKVT 923 Query: 1211 PTSNSKGMIEIVTEA 1225 P S G++E T + Sbjct: 924 PLSMRSGILEWCTNS 938 >AY113192-1|AAM29197.1| 574|Drosophila melanogaster AT01448p protein. Length = 574 Score = 37.5 bits (83), Expect = 0.14 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 7/70 (10%) Query: 1267 FTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDR 1325 +T S A S+ Y+LG+ DRH NI++ + + + HIDFG F K + Sbjct: 393 YTNSVATTSMVGYVLGLGDRHTQNILVDQQTAEVIHIDFG------IAFEQGKIQTTPET 446 Query: 1326 APFVLTHDMV 1335 PF LT D V Sbjct: 447 VPFRLTRDFV 456 Score = 36.3 bits (80), Expect = 0.33 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 4/75 (5%) Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAG----LDLRMVTFQAL 1210 P+KI + +D + + K DDLRQDA++ QV I++ L + L++ T++ Sbjct: 239 PVKIMCVCSDGKIRAQLVKGKDDLRQDAVMQQVFGIVNELLNQDSEFIERKLKLRTYKVT 298 Query: 1211 PTSNSKGMIEIVTEA 1225 P S G++E T + Sbjct: 299 PLSMRSGILEWCTNS 313 >AE014298-963|AAF46207.2| 3218|Drosophila melanogaster CG32743-PA protein. Length = 3218 Score = 37.5 bits (83), Expect = 0.14 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 9/89 (10%) Query: 1259 EYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGHLFHIDFGKFLGDAQMFGNF 1317 E++++ F + S+ Y++G+ DRH DN+++ SG + HID+ F Sbjct: 2078 EWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYN------VCFEKG 2131 Query: 1318 KRLVYIDRAPFVLTHDMVYV--INGGERP 1344 + L ++ PF LT ++V I G E P Sbjct: 2132 RTLRIPEKVPFRLTQNLVQAMGITGIEGP 2160 >AE014297-1966|ABI31168.1| 2767|Drosophila melanogaster CG6535-PB protein. Length = 2767 Score = 37.5 bits (83), Expect = 0.14 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 7/70 (10%) Query: 1267 FTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDR 1325 +T S A S+ Y+LG+ DRH NI++ + + + HIDFG F K + Sbjct: 2586 YTNSVATTSMVGYVLGLGDRHTQNILVDQQTAEVIHIDFG------IAFEQGKIQTTPET 2639 Query: 1326 APFVLTHDMV 1335 PF LT D V Sbjct: 2640 VPFRLTRDFV 2649 Score = 36.3 bits (80), Expect = 0.33 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 4/75 (5%) Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAG----LDLRMVTFQAL 1210 P+KI + +D + + K DDLRQDA++ QV I++ L + L++ T++ Sbjct: 2432 PVKIMCVCSDGKIRAQLVKGKDDLRQDAVMQQVFGIVNELLNQDSEFIERKLKLRTYKVT 2491 Query: 1211 PTSNSKGMIEIVTEA 1225 P S G++E T + Sbjct: 2492 PLSMRSGILEWCTNS 2506 >AJ556818-1|CAD89223.1| 2162|Drosophila melanogaster SMG1 protein protein. Length = 2162 Score = 36.7 bits (81), Expect = 0.25 Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 7/78 (8%) Query: 1259 EYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGHLFHIDFGKFLGDAQMFGNF 1317 E++++ F + S+ Y++G+ DRH DN+++ SG + HID+ F Sbjct: 2078 EWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYN------VCFEKG 2131 Query: 1318 KRLVYIDRAPFVLTHDMV 1335 + L ++ PF LT ++V Sbjct: 2132 RTLRIPEKVPFRLTQNLV 2149 Database: fruitfly Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 24,830,863 Number of sequences in database: 52,641 Lambda K H 0.319 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 67,005,980 Number of Sequences: 52641 Number of extensions: 2652053 Number of successful extensions: 6504 Number of sequences better than 10.0: 36 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 6287 Number of HSP's gapped (non-prelim): 115 length of query: 1505 length of database: 24,830,863 effective HSP length: 95 effective length of query: 1410 effective length of database: 19,829,968 effective search space: 27960254880 effective search space used: 27960254880 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 68 (31.5 bits)
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