Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001268-TA|BGIBMGA001268-PA|IPR011009|Protein
kinase-like, IPR008973|C2 calcium/lipid-binding region, CaLB,
IPR000403|Phosphatidylinositol 3- and 4-kinase, catalytic,
IPR000341|Phosphoinositide 3-kinase, ras-binding,
IPR002420|Phosphoinositide 3-kinase, C2, IPR001263|Phosphoinositide
3-kinase accessory region PIK, IPR001683|Phox-like
(1505 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B5550 Cluster: PREDICTED: similar to phopsphati... 933 0.0
UniRef50_UPI0000DB6BA7 Cluster: PREDICTED: similar to Phosphotid... 913 0.0
UniRef50_Q7JNX6 Cluster: Phosphoinositide 3-kinase; n=5; Diptera... 753 0.0
UniRef50_UPI0000D572A6 Cluster: PREDICTED: similar to CG11621-PA... 753 0.0
UniRef50_Q29DX8 Cluster: GA11104-PA; n=3; Diptera|Rep: GA11104-P... 750 0.0
UniRef50_O00443 Cluster: Phosphatidylinositol-4-phosphate 3-kina... 542 e-152
UniRef50_Q1L913 Cluster: Novel protein similar to vertebrate pho... 499 e-139
UniRef50_O00750 Cluster: Phosphatidylinositol-4-phosphate 3-kina... 475 e-132
UniRef50_A7RRA6 Cluster: Predicted protein; n=2; Nematostella ve... 434 e-120
UniRef50_Q4T9W9 Cluster: Chromosome undetermined SCAF7485, whole... 331 7e-89
UniRef50_UPI0000ECD2E3 Cluster: Phosphatidylinositol-4-phosphate... 312 5e-83
UniRef50_O75747 Cluster: Phosphatidylinositol-4-phosphate 3-kina... 308 8e-82
UniRef50_Q4RSB1 Cluster: Chromosome 13 SCAF15000, whole genome s... 283 3e-74
UniRef50_P54673 Cluster: Phosphatidylinositol 3-kinase 1; n=2; D... 256 3e-66
UniRef50_UPI0000498E9A Cluster: phosphatidylinositol 3-kinase; n... 246 4e-63
UniRef50_P54674 Cluster: Phosphatidylinositol 3-kinase 2; n=2; D... 239 6e-61
UniRef50_P42338 Cluster: Phosphatidylinositol-4,5-bisphosphate 3... 234 1e-59
UniRef50_Q20187 Cluster: Putative uncharacterized protein; n=2; ... 233 4e-59
UniRef50_P54675 Cluster: Phosphatidylinositol 3-kinase 3; n=5; E... 223 2e-56
UniRef50_Q4CUM7 Cluster: Phosphatidylinositol 3-kinase 2, putati... 221 1e-55
UniRef50_UPI0000498754 Cluster: phosphatidylinositol 3-kinase; n... 218 8e-55
UniRef50_Q54S78 Cluster: Putative uncharacterized protein; n=1; ... 215 1e-53
UniRef50_P48736 Cluster: Phosphatidylinositol-4,5-bisphosphate 3... 215 1e-53
UniRef50_UPI0000E48471 Cluster: PREDICTED: similar to phosphoino... 210 2e-52
UniRef50_A0DT78 Cluster: Chromosome undetermined scaffold_62, wh... 210 3e-52
UniRef50_UPI0000D57007 Cluster: PREDICTED: similar to CG4141-PA,... 204 2e-50
UniRef50_P91634 Cluster: Phosphoinositide 3-kinase, Dp110; n=6; ... 202 4e-50
UniRef50_Q241V8 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 202 8e-50
UniRef50_Q22H25 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 201 1e-49
UniRef50_Q17GT9 Cluster: Phosphatidylinositol 3-kinase catalytic... 200 2e-49
UniRef50_A7S2J3 Cluster: Predicted protein; n=1; Nematostella ve... 199 5e-49
UniRef50_Q7QEJ7 Cluster: ENSANGP00000020426; n=1; Anopheles gamb... 198 1e-48
UniRef50_Q237I3 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 198 1e-48
UniRef50_Q5SR50 Cluster: Phosphoinositide-3-kinase, catalytic, d... 195 9e-48
UniRef50_UPI00015B4B40 Cluster: PREDICTED: similar to phosphatid... 193 3e-47
UniRef50_A0D2V1 Cluster: Chromosome undetermined scaffold_35, wh... 193 3e-47
UniRef50_UPI000049A3E6 Cluster: phosphatidylinositol 3-kinase; n... 193 4e-47
UniRef50_A0DLV0 Cluster: Chromosome undetermined scaffold_556, w... 190 2e-46
UniRef50_UPI0000F21165 Cluster: PREDICTED: hypothetical protein;... 188 1e-45
UniRef50_UPI0000EBCA32 Cluster: PREDICTED: hypothetical protein,... 186 3e-45
UniRef50_Q4RYW3 Cluster: Chromosome 16 SCAF14974, whole genome s... 186 4e-45
UniRef50_P42336 Cluster: Phosphatidylinositol-4,5-bisphosphate 3... 183 3e-44
UniRef50_UPI0000499EE5 Cluster: phosphatidylinositol 3-kinase; n... 175 6e-42
UniRef50_UPI00004983C1 Cluster: phosphatidylinositol-4,5-bisphos... 173 4e-41
UniRef50_A2DYA6 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 168 9e-40
UniRef50_A4RAX1 Cluster: Putative uncharacterized protein; n=3; ... 167 2e-39
UniRef50_A2DJM8 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 164 2e-38
UniRef50_A6S8M7 Cluster: Putative uncharacterized protein; n=2; ... 163 3e-38
UniRef50_Q2U4A1 Cluster: Phosphatidylinositol 3-kinase VPS34; n=... 160 3e-37
UniRef50_Q54F55 Cluster: Putative uncharacterized protein; n=1; ... 159 7e-37
UniRef50_A4RU70 Cluster: Predicted protein; n=1; Ostreococcus lu... 154 2e-35
UniRef50_A2DM61 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 152 8e-35
UniRef50_P54676 Cluster: Phosphatidylinositol 3-kinase VPS34-lik... 140 2e-31
UniRef50_Q5BXA1 Cluster: SJCHGC06189 protein; n=1; Schistosoma j... 139 6e-31
UniRef50_P50520 Cluster: Phosphatidylinositol 3-kinase vps34; n=... 139 6e-31
UniRef50_Q8NEB9 Cluster: Phosphatidylinositol 3-kinase catalytic... 138 1e-30
UniRef50_UPI0000DB7C6C Cluster: PREDICTED: similar to Phosphotid... 138 1e-30
UniRef50_Q5KM37 Cluster: Phosphatidylinositol 3-kinase, putative... 136 3e-30
UniRef50_Q7RSM1 Cluster: Phosphatidylinositol 3-kinase vps34-lik... 136 4e-30
UniRef50_Q6C299 Cluster: Yarrowia lipolytica chromosome F of str... 136 4e-30
UniRef50_Q8I3V5 Cluster: Phosphatidylinositol 3-kinase, putative... 135 1e-29
UniRef50_Q2PF84 Cluster: Phosphatidylinositol 4-kinase; n=1; Pic... 134 2e-29
UniRef50_Q6C4B9 Cluster: Yarrowia lipolytica chromosome E of str... 133 3e-29
UniRef50_P22543 Cluster: Phosphatidylinositol 3-kinase VPS34; n=... 133 4e-29
UniRef50_A5K9K5 Cluster: Phosphatidylinositol 3-kinase, putative... 132 5e-29
UniRef50_UPI0000EBCA07 Cluster: PREDICTED: similar to phosphoino... 132 7e-29
UniRef50_Q6CUT6 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 132 7e-29
UniRef50_Q7PMF0 Cluster: ENSANGP00000002906; n=2; Coelomata|Rep:... 132 9e-29
UniRef50_Q75AF0 Cluster: ADL033Wp; n=3; Saccharomycetaceae|Rep: ... 131 2e-28
UniRef50_Q6CQA2 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 129 5e-28
UniRef50_Q9W4X4 Cluster: CG10260-PB; n=4; Sophophora|Rep: CG1026... 129 7e-28
UniRef50_P42339 Cluster: Phosphatidylinositol 3-kinase VPS34; n=... 128 1e-27
UniRef50_Q94125 Cluster: Phosphatidylinositol 3-kinase age-1; n=... 128 2e-27
UniRef50_Q57YM2 Cluster: Phosphatidylinositol 3-kinase, putative... 127 2e-27
UniRef50_UPI00004993D5 Cluster: phosphatidylinositol 3-kinase; n... 127 3e-27
UniRef50_UPI0000DB7272 Cluster: PREDICTED: similar to CG10260-PB... 126 4e-27
UniRef50_P37297 Cluster: Phosphatidylinositol 4-kinase STT4; n=3... 126 4e-27
UniRef50_Q9XW63 Cluster: Putative uncharacterized protein; n=2; ... 125 8e-27
UniRef50_A3LYX2 Cluster: Phosphatidylinositol-4-kinase involved ... 125 1e-26
UniRef50_Q9W1M7 Cluster: CG5373-PA; n=3; Sophophora|Rep: CG5373-... 124 2e-26
UniRef50_UPI00015B61DA Cluster: PREDICTED: similar to phosphatid... 123 4e-26
UniRef50_P39104 Cluster: Phosphatidylinositol 4-kinase PIK1; n=5... 122 6e-26
UniRef50_Q76NU6 Cluster: Similar to Homo sapiens (Human). Phosph... 121 1e-25
UniRef50_Q4QAC9 Cluster: Phosphatidylinositol 3-kinase, putative... 121 2e-25
UniRef50_Q17PY3 Cluster: Phosphatidylinositol 4-kinase; n=4; Coe... 121 2e-25
UniRef50_Q9USR3 Cluster: Phosphatidylinositol kinase; n=1; Schiz... 120 2e-25
UniRef50_O04269 Cluster: Phosphatidylinositol 3-kinase; n=2; cel... 120 3e-25
UniRef50_A2EUN5 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 120 3e-25
UniRef50_A7P941 Cluster: Chromosome chr3 scaffold_8, whole genom... 120 4e-25
UniRef50_A7F5M2 Cluster: Putative uncharacterized protein; n=1; ... 120 4e-25
UniRef50_Q01CW4 Cluster: Phosphatidylinositol 3-kinase; n=2; cel... 119 7e-25
UniRef50_Q9TXI7 Cluster: Related to yeast vacuolar protein sorti... 119 7e-25
UniRef50_A4QVB3 Cluster: Putative uncharacterized protein; n=1; ... 119 7e-25
UniRef50_Q752A9 Cluster: AFR666Cp; n=1; Eremothecium gossypii|Re... 117 3e-24
UniRef50_Q4QSD0 Cluster: PIKa; n=1; Candida parapsilosis|Rep: PI... 117 3e-24
UniRef50_Q2PFD9 Cluster: Phosphatidylinositol 4-kinase; n=1; Pic... 116 4e-24
UniRef50_Q9Y8E4 Cluster: Phosphatidylinositol 3-kinase Pdd1p; n=... 116 5e-24
UniRef50_Q0UWD6 Cluster: Putative uncharacterized protein; n=5; ... 116 5e-24
UniRef50_Q80Y45 Cluster: Pik4ca protein; n=3; Euteleostomi|Rep: ... 116 7e-24
UniRef50_P42356 Cluster: Phosphatidylinositol 4-kinase alpha; n=... 116 7e-24
UniRef50_Q9ZPE1 Cluster: Phosphatidylinositol 4-kinase; n=7; Vir... 115 9e-24
UniRef50_Q8LPD1 Cluster: Phophatdylinositol 4-kinase; n=9; Magno... 114 2e-23
UniRef50_A3LZ98 Cluster: Phosphatidylinositol 4-kinase PIK1alpha... 114 2e-23
UniRef50_UPI000049A205 Cluster: phosphatidylinositol 4-kinase; n... 113 3e-23
UniRef50_Q4P4N2 Cluster: Putative uncharacterized protein; n=1; ... 113 3e-23
UniRef50_O81129 Cluster: Phosphatidylinositol 4-kinase; n=6; Euk... 113 4e-23
UniRef50_Q4WG47 Cluster: Phosphatidylinositol 4-kinase (STT4), p... 112 6e-23
UniRef50_A4R924 Cluster: Putative uncharacterized protein; n=1; ... 111 1e-22
UniRef50_P54677 Cluster: Phosphatidylinositol 4-kinase; n=2; Dic... 111 2e-22
UniRef50_A0CXG8 Cluster: Chromosome undetermined scaffold_30, wh... 110 3e-22
UniRef50_Q4PHG0 Cluster: Putative uncharacterized protein; n=1; ... 110 3e-22
UniRef50_Q4P1B0 Cluster: Putative uncharacterized protein; n=1; ... 109 8e-22
UniRef50_A5E2B6 Cluster: Phosphatidylinositol 4-kinase PIK1a; n=... 109 8e-22
UniRef50_A2FAC3 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 108 1e-21
UniRef50_A2EAP0 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 108 1e-21
UniRef50_Q9W0R8 Cluster: CG7004-PA, isoform A; n=5; Diptera|Rep:... 107 2e-21
UniRef50_Q22UI8 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 107 3e-21
UniRef50_A0BJY8 Cluster: Chromosome undetermined scaffold_111, w... 106 4e-21
UniRef50_Q4Q2I5 Cluster: Phosphatidylinositol 4-kinase, putative... 106 5e-21
UniRef50_Q5KEG3 Cluster: 1-phosphatidylinositol 4-kinase, putati... 105 9e-21
UniRef50_A2F7A3 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 105 1e-20
UniRef50_A6R342 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-20
UniRef50_Q9UW20 Cluster: Phosphatidylinositol 4-kinase PIK1alpha... 105 1e-20
UniRef50_Q0CTY2 Cluster: Putative uncharacterized protein; n=2; ... 104 2e-20
UniRef50_A2R164 Cluster: Contig An13c0010, complete genome; n=5;... 104 2e-20
UniRef50_Q4SSV6 Cluster: Chromosome undetermined SCAF14347, whol... 104 2e-20
UniRef50_A5DM56 Cluster: Putative uncharacterized protein; n=1; ... 104 2e-20
UniRef50_Q9C680 Cluster: Phosphatidylinositol 4-kinase, putative... 103 3e-20
UniRef50_Q9UW24 Cluster: Phosphatidylinositol 4-kinase PIK1a; n=... 103 3e-20
UniRef50_Q4FXQ9 Cluster: Phosphatidylinositol-kinase domain prot... 103 4e-20
UniRef50_Q16WA0 Cluster: Phosphatidylinositol 4-kinase; n=1; Aed... 103 5e-20
UniRef50_A7AWF1 Cluster: Phosphatidylinositol 3-and 4-kinase dom... 102 7e-20
UniRef50_UPI00006CFDD2 Cluster: Phosphatidylinositol 3- and 4-ki... 101 2e-19
UniRef50_UPI00003BFBA7 Cluster: PREDICTED: similar to four wheel... 101 2e-19
UniRef50_Q4RFL9 Cluster: Chromosome undetermined SCAF15114, whol... 101 2e-19
UniRef50_Q4SZT6 Cluster: Chromosome undetermined SCAF11492, whol... 100 3e-19
UniRef50_UPI0000D5729C Cluster: PREDICTED: similar to CG7004-PA,... 99 8e-19
UniRef50_A4VDF9 Cluster: Phosphatidylinositol 4-kinase; n=1; Tet... 99 8e-19
UniRef50_A4VDB8 Cluster: Phosphatidylinositol 4-kinase; n=1; Tet... 99 1e-18
UniRef50_Q2H8U5 Cluster: Putative uncharacterized protein; n=4; ... 99 1e-18
UniRef50_Q4S209 Cluster: Chromosome undetermined SCAF14764, whol... 98 1e-18
UniRef50_A2YTT1 Cluster: Putative uncharacterized protein; n=2; ... 98 1e-18
UniRef50_Q20077 Cluster: Putative uncharacterized protein; n=2; ... 98 1e-18
UniRef50_A0BV54 Cluster: Chromosome undetermined scaffold_13, wh... 98 1e-18
UniRef50_Q9UBF8 Cluster: Phosphatidylinositol 4-kinase beta; n=4... 98 1e-18
UniRef50_Q22WE1 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 97 4e-18
UniRef50_A0EDW6 Cluster: Chromosome undetermined scaffold_90, wh... 97 4e-18
UniRef50_Q5CK49 Cluster: Phosphatidylinositol 3-kinase, root iso... 96 6e-18
UniRef50_Q4D3R3 Cluster: Phosphatidylinositol-kinase domain prot... 96 8e-18
UniRef50_Q4CMW1 Cluster: Phosphatidylinositol 4-kinase, putative... 95 1e-17
UniRef50_A0CV19 Cluster: Chromosome undetermined scaffold_29, wh... 95 1e-17
UniRef50_Q6CFY9 Cluster: Yarrowia lipolytica chromosome B of str... 94 3e-17
UniRef50_Q4N7K0 Cluster: Phosphatidylinositol 4-kinase, putative... 93 4e-17
UniRef50_A0DG06 Cluster: Chromosome undetermined scaffold_5, who... 93 4e-17
UniRef50_Q8I406 Cluster: Phosphatidylinositol 4-kinase, putative... 93 5e-17
UniRef50_Q54LR9 Cluster: Phosphatidylinositol 4-kinase; n=1; Dic... 93 5e-17
UniRef50_Q10366 Cluster: Uncharacterized PI3/PI4-kinase family p... 93 5e-17
UniRef50_UPI0001509F2E Cluster: Phosphatidylinositol 3- and 4-ki... 92 9e-17
UniRef50_Q5CWX0 Cluster: Membrane associated protein with 2 tran... 92 9e-17
UniRef50_A5KB26 Cluster: Phosphatidylinositol 4-kinase, putative... 92 1e-16
UniRef50_Q7RHE8 Cluster: Phosphatidylinositol 4-kinase-related; ... 91 2e-16
UniRef50_A0C4X5 Cluster: Chromosome undetermined scaffold_15, wh... 91 2e-16
UniRef50_A4QPH2 Cluster: LOC375133 protein; n=8; Eutheria|Rep: L... 89 9e-16
UniRef50_Q57WD8 Cluster: Phosphatidylinositol 4-kinase alpha, pu... 87 3e-15
UniRef50_Q4U9S5 Cluster: Phosphatidylinositol 4-kinase, putative... 87 5e-15
UniRef50_A7ARY7 Cluster: Phosphatidylinositol 4 kinase, putative... 85 2e-14
UniRef50_A0E590 Cluster: Chromosome undetermined scaffold_79, wh... 84 2e-14
UniRef50_Q8SS90 Cluster: PHOSPHATIDYLINOSITOL-4-KINASE CATALYTIC... 84 3e-14
UniRef50_Q23R89 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 82 1e-13
UniRef50_Q8SR56 Cluster: PHOSPHATIDYL INOSITOL-3-KINASE; n=1; En... 82 1e-13
UniRef50_A0ED64 Cluster: Chromosome undetermined scaffold_9, who... 81 2e-13
UniRef50_Q5UR69 Cluster: Putative uncharacterized protein; n=1; ... 80 5e-13
UniRef50_Q7R239 Cluster: GLP_630_45311_38844; n=1; Giardia lambl... 80 5e-13
UniRef50_A7ATH3 Cluster: 1-phosphatidylinositol 4-kinase, putati... 80 5e-13
UniRef50_Q7QSW7 Cluster: GLP_44_18876_25655; n=2; Giardia intest... 79 9e-13
UniRef50_A0BVP3 Cluster: Chromosome undetermined scaffold_130, w... 79 9e-13
UniRef50_Q6C0Z0 Cluster: Yarrowia lipolytica chromosome F of str... 78 2e-12
UniRef50_Q5CVD3 Cluster: Phosphatidylinositol 4-kinase; n=2; Cry... 76 7e-12
UniRef50_Q5KGM7 Cluster: UVSB PI-3 kinase, putative; n=2; Filoba... 74 3e-11
UniRef50_Q5C275 Cluster: SJCHGC06440 protein; n=1; Schistosoma j... 73 6e-11
UniRef50_Q54UU9 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-10
UniRef50_Q00UA0 Cluster: Phosphatidylinositol 4-kinase, putative... 70 4e-10
UniRef50_Q6CAD2 Cluster: Serine/threonine-protein kinase TEL1; n... 70 4e-10
UniRef50_A7T8E9 Cluster: Predicted protein; n=1; Nematostella ve... 67 3e-09
UniRef50_A3LQL4 Cluster: 1-phosphatidylinositol 3-kinase; n=2; S... 66 5e-09
UniRef50_UPI0000F1FBED Cluster: PREDICTED: similar to phosphoino... 65 1e-08
UniRef50_Q92213 Cluster: Phosphatidylinositol 3-kinase VPS34; n=... 65 1e-08
UniRef50_A2F4J8 Cluster: PIKK family atypical protein kinase; n=... 64 4e-08
UniRef50_A7TLR7 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-08
UniRef50_A0E0Q4 Cluster: Chromosome undetermined scaffold_72, wh... 63 6e-08
UniRef50_Q98RM0 Cluster: Phosphatidylinositol 4-kinase; n=1; Gui... 62 1e-07
UniRef50_A5DR49 Cluster: Putative uncharacterized protein; n=1; ... 61 2e-07
UniRef50_Q4DM49 Cluster: Phosphatidylinositol kinase, putative; ... 60 6e-07
UniRef50_Q4RZF8 Cluster: Chromosome 3 SCAF14932, whole genome sh... 59 8e-07
UniRef50_UPI0000661579 Cluster: Homolog of Danio rerio "Phosphoi... 59 1e-06
UniRef50_Q0UIR4 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-06
UniRef50_A0CIQ9 Cluster: Chromosome undetermined scaffold_19, wh... 58 1e-06
UniRef50_Q6PJ60 Cluster: PIK3CB protein; n=8; Euteleostomi|Rep: ... 58 2e-06
UniRef50_Q7R0U5 Cluster: GLP_186_22597_27513; n=1; Giardia lambl... 58 2e-06
UniRef50_Q1JTH0 Cluster: Phosphatidylinositol 4-kinase, putative... 57 3e-06
UniRef50_Q1DMF1 Cluster: Putative uncharacterized protein; n=1; ... 57 3e-06
UniRef50_Q5AXK5 Cluster: Putative uncharacterized protein; n=1; ... 57 4e-06
UniRef50_UPI0000E49F1A Cluster: PREDICTED: similar to Pik3c3-pro... 56 6e-06
UniRef50_A5K647 Cluster: Phosphatidylinositol 3-and 4-kinase, pu... 56 6e-06
UniRef50_Q24FA9 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 56 7e-06
UniRef50_Q8SSE7 Cluster: PROTEIN KINASE OF THE PI3/PI4 FAMILY; n... 56 7e-06
UniRef50_Q1XH09 Cluster: Phosphatidyl inositol 3-kinase; n=1; Ne... 56 1e-05
UniRef50_A6SF30 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-05
UniRef50_A7QH41 Cluster: Chromosome chr3 scaffold_95, whole geno... 55 2e-05
UniRef50_A2DPS8 Cluster: PIKK family atypical protein kinase; n=... 55 2e-05
UniRef50_UPI00006CBC83 Cluster: Phosphatidylinositol 3- and 4-ki... 54 2e-05
UniRef50_Q38GA3 Cluster: Target of rapamycin kinase; n=2; Chloro... 54 2e-05
UniRef50_Q4DEX9 Cluster: Phosphatidylinositol 3-related kinase, ... 54 2e-05
UniRef50_A7F1X6 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-05
UniRef50_A4RPR6 Cluster: Putative uncharacterized protein; n=4; ... 54 2e-05
UniRef50_A2ELE0 Cluster: PIKK family atypical protein kinase; n=... 54 3e-05
UniRef50_Q54TG2 Cluster: Protein kinase, Atypical group; n=2; Di... 54 4e-05
UniRef50_Q2I6W1 Cluster: Target of rapamycin; n=4; Sordariomycet... 54 4e-05
UniRef50_Q2GTI4 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-05
UniRef50_Q9VK45 Cluster: CG5092-PA; n=9; Eumetazoa|Rep: CG5092-P... 53 5e-05
UniRef50_UPI00006CBC84 Cluster: Phosphatidylinositol 3- and 4-ki... 53 7e-05
UniRef50_Q2KGF1 Cluster: Putative uncharacterized protein; n=2; ... 53 7e-05
UniRef50_A5E2Q8 Cluster: Putative uncharacterized protein; n=1; ... 53 7e-05
UniRef50_A4RC96 Cluster: Putative uncharacterized protein; n=1; ... 53 7e-05
UniRef50_Q9LPM4 Cluster: F2J10.9 protein; n=3; Arabidopsis thali... 52 9e-05
UniRef50_A2ELF3 Cluster: PIKK family atypical protein kinase; n=... 52 9e-05
UniRef50_A1C8Y6 Cluster: Phosphatidylinositol 3-and 4-kinase, pu... 52 9e-05
UniRef50_P38110 Cluster: Serine/threonine-protein kinase TEL1; n... 52 9e-05
UniRef50_UPI0000DB7A76 Cluster: PREDICTED: similar to DNA-depend... 52 1e-04
UniRef50_UPI000049A59C Cluster: protein kinase; n=1; Entamoeba h... 52 1e-04
UniRef50_Q5C1Z3 Cluster: SJCHGC04717 protein; n=1; Schistosoma j... 52 1e-04
UniRef50_Q4Q288 Cluster: Phosphatidylinositol 3-kinase (Tor2)-li... 52 1e-04
UniRef50_Q2H501 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-04
UniRef50_A7F5R9 Cluster: Putative uncharacterized protein; n=2; ... 52 1e-04
UniRef50_A2E6E9 Cluster: PIKK family atypical protein kinase; n=... 52 2e-04
UniRef50_A6RDF6 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-04
UniRef50_A5E5B4 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-04
UniRef50_P42345 Cluster: FKBP12-rapamycin complex-associated pro... 52 2e-04
UniRef50_Q6CT34 Cluster: Serine/threonine-protein kinase MEC1; n... 52 2e-04
UniRef50_Q5EFI5 Cluster: Target of rapamycin; n=5; Poaceae|Rep: ... 51 2e-04
UniRef50_A2D9E8 Cluster: PIKK family atypical protein kinase; n=... 51 2e-04
UniRef50_Q95Q95 Cluster: Target of rapamycin homolog; n=5; Caeno... 51 2e-04
UniRef50_P38111 Cluster: Serine/threonine-protein kinase MEC1; n... 51 2e-04
UniRef50_Q75DB8 Cluster: Serine/threonine-protein kinase MEC1; n... 51 2e-04
UniRef50_Q6BV76 Cluster: Serine/threonine-protein kinase TEL1; n... 51 2e-04
UniRef50_A2FZM6 Cluster: PIKK family atypical protein kinase; n=... 51 3e-04
UniRef50_A2DII8 Cluster: PIKK family atypical protein kinase; n=... 51 3e-04
UniRef50_UPI00015B5AD2 Cluster: PREDICTED: similar to fkbp-rapam... 50 4e-04
UniRef50_UPI0000D56D93 Cluster: PREDICTED: similar to CG5092-PA;... 50 4e-04
UniRef50_A2ESW1 Cluster: PIKK family atypical protein kinase; n=... 50 4e-04
UniRef50_A2ERB7 Cluster: PIKK family atypical protein kinase; n=... 50 4e-04
UniRef50_A0DCX6 Cluster: Chromosome undetermined scaffold_46, wh... 50 4e-04
UniRef50_Q9VXG8 Cluster: Serine/threonine-protein kinase ATR; n=... 50 4e-04
UniRef50_UPI000049934E Cluster: FKBP-rapamycin associated protei... 50 5e-04
UniRef50_Q7Q0G1 Cluster: ENSANGP00000018055; n=1; Anopheles gamb... 50 5e-04
UniRef50_Q4Q5D6 Cluster: Phosphatidylinositol 3-related kinase, ... 50 5e-04
UniRef50_UPI0000D56C40 Cluster: PREDICTED: similar to Serine-pro... 50 6e-04
UniRef50_Q02099 Cluster: Protein kinase rad3; n=1; Schizosacchar... 50 6e-04
UniRef50_UPI00015B49DA Cluster: PREDICTED: similar to esr1 prote... 49 9e-04
UniRef50_Q753A4 Cluster: AFR420Wp; n=6; Eukaryota|Rep: AFR420Wp ... 49 9e-04
UniRef50_Q22258 Cluster: Serine/threonine-protein kinase ATR; n=... 49 9e-04
UniRef50_Q580A8 Cluster: Putative uncharacterized protein; n=2; ... 49 0.001
UniRef50_Q4Q2E8 Cluster: Phosphatidylinositol 3-kinase-like prot... 49 0.001
UniRef50_A2G2C3 Cluster: PIKK family atypical protein kinase; n=... 49 0.001
UniRef50_Q2U032 Cluster: DNA-dependent protein kinase; n=13; Asc... 49 0.001
UniRef50_Q2PIY8 Cluster: Protein kinase of the PI-3 kinase famil... 49 0.001
UniRef50_UPI0000D57685 Cluster: PREDICTED: similar to DNA-depend... 48 0.001
UniRef50_A6REM9 Cluster: Putative uncharacterized protein; n=1; ... 48 0.001
UniRef50_P32600 Cluster: Serine/threonine-protein kinase TOR2; n... 48 0.001
UniRef50_Q13535 Cluster: Serine/threonine-protein kinase ATR; n=... 48 0.001
UniRef50_UPI0000499CCB Cluster: Phosphatidylinositol 3-kinase; n... 48 0.002
UniRef50_A4RRV4 Cluster: Predicted protein; n=1; Ostreococcus lu... 48 0.002
UniRef50_Q54UC0 Cluster: DNA-dependent protein kinase (DNAPK) su... 48 0.002
UniRef50_Q381W7 Cluster: Phosphatidylinositol 3-related kinase, ... 48 0.002
UniRef50_A2DGF0 Cluster: PIKK family atypical protein kinase; n=... 48 0.002
UniRef50_Q5KEY7 Cluster: Phosphatidylinositol 3-kinase TOR1; n=4... 48 0.002
UniRef50_Q38AC2 Cluster: Phosphatidylinositol 3 kinase, putative... 48 0.003
UniRef50_Q16TZ4 Cluster: Esr1 protein; n=1; Aedes aegypti|Rep: E... 48 0.003
UniRef50_A2FK60 Cluster: PIKK family atypical protein kinase; n=... 48 0.003
UniRef50_A2EN34 Cluster: PIKK family atypical protein kinase; n=... 48 0.003
UniRef50_Q00XW6 Cluster: DNA-dependent protein kinase catalytic ... 47 0.003
UniRef50_Q54ER4 Cluster: Protein kinase, Atypical group; n=1; Di... 47 0.003
UniRef50_A7AQ66 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 47 0.003
UniRef50_UPI0000498E8A Cluster: Phosphatidylinositol 3- and 4-ki... 47 0.005
UniRef50_A5BP90 Cluster: Putative uncharacterized protein; n=2; ... 47 0.005
UniRef50_Q4Q0C8 Cluster: Phosphatidylinositol 3 kinase, putative... 47 0.005
UniRef50_Q381Q2 Cluster: Phosphatidylinositol 3-kinase catalytic... 47 0.005
UniRef50_A2EZL1 Cluster: PIKK family atypical protein kinase; n=... 47 0.005
UniRef50_A2DX13 Cluster: PIKK family atypical protein kinase; n=... 47 0.005
UniRef50_Q6BND8 Cluster: Debaryomyces hansenii chromosome E of s... 47 0.005
UniRef50_Q5ABX0 Cluster: Serine/threonine-protein kinase TEL1; n... 47 0.005
UniRef50_Q751J3 Cluster: Serine/threonine-protein kinase TEL1; n... 47 0.005
UniRef50_Q00XW5 Cluster: ATM_ARATH Serine-protein kinase ATM; n=... 46 0.006
UniRef50_Q4P9J7 Cluster: Putative uncharacterized protein; n=1; ... 46 0.006
UniRef50_O74630 Cluster: Serine/threonine-protein kinase tel1; n... 46 0.006
UniRef50_Q57UT3 Cluster: Phosphatidylinositol 3-kinase tor, puta... 46 0.008
UniRef50_A7KAK9 Cluster: Protein kinase TOR; n=1; Pichia angusta... 46 0.008
UniRef50_Q4TAJ3 Cluster: Chromosome undetermined SCAF7304, whole... 46 0.011
UniRef50_A2FVZ7 Cluster: PIKK family atypical protein kinase; n=... 46 0.011
UniRef50_Q9Y7K2 Cluster: Phosphatidylinositol 3-kinase tor2; n=6... 46 0.011
UniRef50_O01510 Cluster: Serine/threonine-protein kinase smg-1; ... 46 0.011
UniRef50_UPI00015B58E4 Cluster: PREDICTED: hypothetical protein;... 45 0.014
UniRef50_Q5TPC2 Cluster: ENSANGP00000025430; n=1; Anopheles gamb... 45 0.014
UniRef50_Q5C5N3 Cluster: SJCHGC04590 protein; n=1; Schistosoma j... 45 0.014
UniRef50_Q4LBF0 Cluster: DNA-dependent protein kinase catalytic ... 45 0.014
UniRef50_A2DWS3 Cluster: PIKK family atypical protein kinase; n=... 45 0.014
UniRef50_Q4PFK3 Cluster: Putative uncharacterized protein; n=1; ... 45 0.014
UniRef50_Q59LR2 Cluster: Serine/threonine-protein kinase MEC1; n... 45 0.014
UniRef50_A4S0K2 Cluster: Predicted protein; n=2; Ostreococcus|Re... 45 0.018
UniRef50_A2E2R5 Cluster: PIKK family atypical protein kinase; n=... 45 0.018
UniRef50_Q586K5 Cluster: Phosphatidylinositol kinase domain prot... 44 0.024
UniRef50_A2F9M3 Cluster: PIKK family atypical protein kinase; n=... 44 0.024
UniRef50_UPI0000DB74DC Cluster: PREDICTED: similar to Serine-pro... 44 0.032
UniRef50_Q8I6M7 Cluster: Phosphatidylinositol kinase-related kin... 44 0.032
UniRef50_Q16RJ6 Cluster: Fkbp-rapamycin associated protein; n=1;... 44 0.032
UniRef50_A7SIS1 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.042
UniRef50_A2E491 Cluster: PIKK family atypical protein kinase; n=... 44 0.042
UniRef50_A2DPM5 Cluster: PIKK family atypical protein kinase; n=... 44 0.042
UniRef50_A2DG61 Cluster: PIKK family atypical protein kinase; n=... 44 0.042
UniRef50_UPI00004997EB Cluster: hypothetical protein 312.t00005;... 43 0.056
UniRef50_UPI000069FCE5 Cluster: SH3 and PX domain-containing pro... 43 0.056
UniRef50_Q4GZ26 Cluster: Phosphatidylinositol 3-kinase, putative... 43 0.056
UniRef50_A7TI29 Cluster: Putative uncharacterized protein; n=1; ... 43 0.056
UniRef50_UPI00006615F6 Cluster: DNA-dependent protein kinase cat... 43 0.074
UniRef50_Q0D9E3 Cluster: Os06g0724700 protein; n=2; Oryza sativa... 43 0.074
UniRef50_A2FS60 Cluster: PIKK family atypical protein kinase; n=... 43 0.074
UniRef50_A2F6I1 Cluster: PIKK family atypical protein kinase; n=... 43 0.074
UniRef50_A2YH41 Cluster: Serine/threonine-protein kinase ATR; n=... 43 0.074
UniRef50_Q6CP76 Cluster: Serine/threonine-protein kinase TEL1; n... 43 0.074
UniRef50_UPI00015B618D Cluster: PREDICTED: similar to mutated in... 42 0.098
UniRef50_Q7Q293 Cluster: ENSANGP00000002762; n=1; Anopheles gamb... 42 0.098
UniRef50_Q5CQZ9 Cluster: FRP1 like protein involved in DNA repai... 42 0.098
UniRef50_A2EA88 Cluster: PIKK family atypical protein kinase; n=... 42 0.098
UniRef50_Q9FKS4 Cluster: Serine/threonine-protein kinase ATR; n=... 42 0.098
UniRef50_A2FB39 Cluster: PIKK family atypical protein kinase; n=... 42 0.13
UniRef50_A2ETI7 Cluster: PIKK family atypical protein kinase; n=... 42 0.13
UniRef50_A2ELA2 Cluster: PIKK family atypical protein kinase; n=... 42 0.13
UniRef50_A2DQ06 Cluster: PIKK family atypical protein kinase; n=... 42 0.13
UniRef50_A3LT76 Cluster: Phosphatidylinositol kinase; n=1; Pichi... 42 0.13
UniRef50_UPI000035FBE6 Cluster: Homolog of Homo sapiens "OTTHUMP... 42 0.17
UniRef50_Q0JRD6 Cluster: Os01g0106700 protein; n=3; Oryza sativa... 42 0.17
UniRef50_Q553E9 Cluster: Protein kinase, Atypical group; n=2; Di... 42 0.17
UniRef50_Q4Q7B0 Cluster: Phosphatidylinositol kinase, putative; ... 42 0.17
UniRef50_A2DTB0 Cluster: PIKK family atypical protein kinase; n=... 42 0.17
UniRef50_A1X283 Cluster: Adaptor protein HOFI; n=32; Euteleostom... 42 0.17
UniRef50_UPI0000DB781D Cluster: PREDICTED: similar to PI-3-kinas... 41 0.23
UniRef50_Q1A3S1 Cluster: P47phox; n=1; Siniperca chuatsi|Rep: P4... 41 0.23
UniRef50_Q7QF93 Cluster: ENSANGP00000021947; n=1; Anopheles gamb... 41 0.23
UniRef50_Q5K8Y1 Cluster: Phosphatidylinositol 3-kinase, putative... 41 0.23
UniRef50_Q2H947 Cluster: Putative uncharacterized protein; n=1; ... 41 0.23
UniRef50_Q7RZT9 Cluster: Serine/threonine-protein kinase tel-1; ... 41 0.23
UniRef50_Q6FRZ9 Cluster: Serine/threonine-protein kinase TEL1; n... 41 0.23
UniRef50_UPI0000498472 Cluster: hypothetical protein 29.t00031; ... 41 0.30
UniRef50_A7P8H4 Cluster: Chromosome chr3 scaffold_8, whole genom... 41 0.30
UniRef50_A2DVG3 Cluster: PIKK family atypical protein kinase; n=... 41 0.30
UniRef50_Q96Q15 Cluster: Serine/threonine-protein kinase SMG1; n... 41 0.30
UniRef50_A0EII8 Cluster: Chromosome undetermined scaffold_99, wh... 40 0.40
UniRef50_A6S248 Cluster: Putative uncharacterized protein; n=1; ... 40 0.40
UniRef50_P78527 Cluster: DNA-dependent protein kinase catalytic ... 40 0.40
UniRef50_Q13315 Cluster: Serine-protein kinase ATM; n=48; Tetrap... 40 0.40
UniRef50_Q6B9P2 Cluster: Phosphatydilinositol 3-kinase; n=2; cor... 40 0.52
UniRef50_Q294C2 Cluster: GA19668-PA; n=2; Sophophora|Rep: GA1966... 40 0.52
UniRef50_Q2U639 Cluster: Serine/threonine-protein kinase tel1; n... 40 0.52
UniRef50_Q4WVM7 Cluster: Serine/threonine-protein kinase tel1; n... 40 0.52
UniRef50_UPI0000D575C3 Cluster: PREDICTED: similar to ataxia tel... 40 0.69
UniRef50_Q16F49 Cluster: Ataxia telangiectasia mutated; n=1; Aed... 40 0.69
UniRef50_A7ED35 Cluster: Putative uncharacterized protein; n=1; ... 40 0.69
UniRef50_A2FRM9 Cluster: PIKK family atypical protein kinase; n=... 39 0.91
UniRef50_Q0UD07 Cluster: Putative uncharacterized protein; n=1; ... 39 0.91
UniRef50_A7EWK2 Cluster: Putative uncharacterized protein; n=1; ... 39 0.91
UniRef50_Q5TCZ1 Cluster: SH3 and PX domain-containing protein 2A... 39 0.91
UniRef50_Q4IB89 Cluster: Serine/threonine-protein kinase TEL1; n... 39 0.91
UniRef50_UPI0000589301 Cluster: PREDICTED: similar to SH3 and PX... 39 1.2
UniRef50_Q10D72 Cluster: Phosphatidylinositol 3-and 4-kinase fam... 39 1.2
UniRef50_Q4T861 Cluster: Chromosome undetermined SCAF7887, whole... 38 1.6
UniRef50_Q5BYQ1 Cluster: SJCHGC08211 protein; n=1; Schistosoma j... 38 1.6
UniRef50_A7SPT8 Cluster: Predicted protein; n=1; Nematostella ve... 38 1.6
UniRef50_UPI00015B6020 Cluster: PREDICTED: similar to Serine/thr... 38 2.1
UniRef50_UPI00015555FC Cluster: PREDICTED: similar to NADPH oxid... 38 2.1
UniRef50_UPI0000D5591E Cluster: PREDICTED: similar to PI-3-kinas... 38 2.1
UniRef50_Q4N452 Cluster: Putative uncharacterized protein; n=1; ... 38 2.1
UniRef50_A7SUI4 Cluster: Predicted protein; n=1; Nematostella ve... 38 2.1
UniRef50_Q5KFE0 Cluster: Serine/threonine-protein kinase TEL1; n... 38 2.1
UniRef50_A6C5V2 Cluster: Putative uncharacterized protein; n=1; ... 38 2.8
UniRef50_A7RJW4 Cluster: Predicted protein; n=1; Nematostella ve... 38 2.8
UniRef50_Q70PP2 Cluster: Serine/threonine-protein kinase Smg1; n... 38 2.8
UniRef50_Q5EAK6 Cluster: Serine/threonine-protein kinase ATM; n=... 38 2.8
UniRef50_Q4SRE1 Cluster: Chromosome undetermined SCAF14527, whol... 37 3.7
UniRef50_Q4S2U2 Cluster: Chromosome 17 SCAF14760, whole genome s... 37 3.7
UniRef50_Q9M3G7 Cluster: Serine/threonine-protein kinase ATM; n=... 37 3.7
UniRef50_Q9N3Q4 Cluster: Atm (Ataxia telangectasia mutated) fami... 37 4.9
UniRef50_P14598 Cluster: Neutrophil cytosol factor 1; n=50; Eute... 37 4.9
UniRef50_Q59IS5 Cluster: Ataxia telangiectasia mutated; n=13; ce... 36 6.4
UniRef50_Q4DJR5 Cluster: Phosphatidylinositol kinase domain prot... 36 6.4
UniRef50_Q22BE5 Cluster: HhH-GPD superfamily base excision DNA r... 36 6.4
UniRef50_UPI0000499A89 Cluster: hypothetical protein 156.t00011;... 36 8.5
>UniRef50_UPI00015B5550 Cluster: PREDICTED: similar to
phopsphatidylinositol 3-kinase, putative; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
phopsphatidylinositol 3-kinase, putative - Nasonia
vitripennis
Length = 1772
Score = 933 bits (2310), Expect = 0.0
Identities = 560/1328 (42%), Positives = 742/1328 (55%), Gaps = 113/1328 (8%)
Query: 250 NLIDFGGRNPNGSQGSVRVSVLEAFDPLL-----TEQSNPEYAV--------GSECSSSV 296
NLID + +VRVSVLEAFDPLL T++ E A S+ SV
Sbjct: 286 NLIDLSVFEHIEDKTNVRVSVLEAFDPLLIKTFKTDEPREEAAATKGSTDDTSSQMEGSV 345
Query: 297 YEEYDPLDFLYGETE-MRETPVYGTVGKREXXXXXXXXX------XXXXXXXXXXLRSTT 349
Y+ +DP D++Y +E + PVY V K R T+
Sbjct: 346 YDPFDPFDYMYSTSETVNSDPVYAAVDKSTKSPAVSPAAPPPLPPRNSSAWNTIERRRTS 405
Query: 350 --------NKLYDSI--VKIRTRNYDSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARS 399
+LY+++ VK R +D + AF KM VR +F + D TN GHVI+
Sbjct: 406 LDRRQKRQTRLYENVNVVKARASLHDCDLVAFHKMVKSVRGEFPFNDPSTNIGHVISPMM 465
Query: 400 GGKYPPNTSIKILVHHAHSDE------PITFTSDVESKVEHVILTVVCSLDEDIREDMSG 453
YP NTSIK++VH S E I+FT DV VEHVI V CSL+++ +
Sbjct: 466 ESSYPENTSIKLIVHSKMSSEGKDCTPSISFTCDVNCSVEHVIFNVACSLEDEDTVNAEK 525
Query: 454 YMLRVRGAKEYLTPGSSLSEYDYIRECVRLEKDVTLCLHEGRDS--TLARTERDDAKDSH 511
Y LRV G EYL P +++++Y+Y+ +C++LEKD+ L L ++ART +DD +D
Sbjct: 526 YCLRVWGLAEYLAPNTTIAQYEYVHQCIKLEKDIELALETKAQMKVSIARTLQDDNRDQC 585
Query: 512 LTLDDLFPAQGATPMLSFDNLSILLETLEGELSRAIGV-----TSAEGSC-----SPKAV 561
L L+D+ P + P +S+D L ILLET+E E+ R TS+ GS P+ V
Sbjct: 586 LKLEDILPNEPLQP-ISYDTLLILLETVEKEMERVESTAAQLATSSHGSSLLPQLQPRGV 644
Query: 562 FQAVKAICALAGGVETLHVTHTLNAFAQACTA-----QGAN-NVVRPEIEREQGAYCSVS 615
Q VKA+CAL G +ET +T ++ F AC AN +PEI E G Y V+
Sbjct: 645 VQTVKAVCALMGNIETYEITEAVDNFVNACCKFLPQMHTANIECKKPEILHEDGDYSVVT 704
Query: 616 LAAGSRRDCVSLQGGRVRDAVXXXXXXXXXXXXXDFRLADAHYQAPANPAKAVPAHTISE 675
L D +S ++RDAV DF+L+ + + P N + + + +
Sbjct: 705 LRT-KFPDVISTHCNKIRDAVQDLVETYCHAFRVDFQLS-SRGEYPTN---TLISSQVID 759
Query: 676 TTLFCIEAVHCLPLCWSHDEYMFHAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWL 735
T L + A+H LP W HD+Y+ AQI+HGTRP+ ++ FYP+I+F++WL
Sbjct: 760 TVLVRVGALHRLPSSWKHDDYIVAAQIFHGTRPVGNPVLSEPMTAGHSNFYPKILFNSWL 819
Query: 736 NLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWA 795
L V +PRE+RLVL ++GRTQ+ +D + NS SS E E ELGW
Sbjct: 820 EFRGLSVCQVPREARLVLVVYGRTQQPVDHE---SNSAESSMEKE----------ELGWG 866
Query: 796 ALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXX-VVNIEIPLYAHTGVK 854
A+Q FD+DG++S G++ L LWP D+R ++ +E+P Y G K
Sbjct: 867 AIQFFDYDGVMSQGSFFLSLWPAVADKRLGPAPAPGIHPHGDTHPIIGLELPDY---GGK 923
Query: 855 WTSGEEDKQKNISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQ 914
E + +I D F+SLD +TQ L ++ EQ + R P + RE++WEKR YL +
Sbjct: 924 VLFPTELRDHDIESLD---FNSLDRNTQELLTYITEQDTFSRPPIDEREILWEKRHYLHE 980
Query: 915 IPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLN 974
P ALP VLLAA +W L LR+W P+ A+ LLLPCFPD+ VRE A +
Sbjct: 981 KPEALPKVLLAAHSWDWACLPDLHASLRVWSPLPPVQALQLLLPCFPDMKVRELAVSRIR 1040
Query: 975 EMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQA 1034
E+++D+L LPQL QAL+HETY +WLL +LP Q+
Sbjct: 1041 ELTNDELVDYLPQLLQALKHETYEASPLARFLLERALLSPRVAHHIYWLLNQALPG--QS 1098
Query: 1035 PHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLC 1094
P Q I+L D+ S + R LMLRALL I G+ L + + QQ LVK+L
Sbjct: 1099 P-QNSSEISLGDDKSLSFARYHR-----RLQLMLRALLAIIGDALRNSFMAQQFLVKNLH 1152
Query: 1095 EMAVSVKCAKEXXXXXXXXXXXXXXX-XXXXXQPTALPLALHKYVHDLDVKSCTYFSSNT 1153
E+A ++K KE + T LPL+ + V ++V++C+YF S T
Sbjct: 1153 EVAENIKTTKESLRLEALKVGLQNINCQLVEDEGTCLPLSPSRQVIGINVQTCSYFPSFT 1212
Query: 1154 LPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTS 1213
LPLKINF+G DN PA+FKVGDDL+QD L +Q+++IMD LWLK GLDL+MVTF +PT
Sbjct: 1213 LPLKINFVGCDNDTSPAIFKVGDDLQQDMLTIQMVRIMDKLWLKEGLDLKMVTFACVPTG 1272
Query: 1214 NSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAG 1273
+GMIE+VT AETLR IQ E+GLTGSFKD+PIAEWLAKHNPSELEY+RA +NFTASCAG
Sbjct: 1273 FKRGMIEMVTNAETLRKIQVEFGLTGSFKDRPIAEWLAKHNPSELEYERAVENFTASCAG 1332
Query: 1274 YSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHD 1333
YSVATY+LGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR DR PFVLT D
Sbjct: 1333 YSVATYILGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR----DRTPFVLTSD 1388
Query: 1334 MVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGSERTVAGGRPQ 1393
M YVINGG++P+ +F HFVELCC AFN+VR H + IL LF L + A Q
Sbjct: 1389 MAYVINGGDKPSAKFHHFVELCCQAFNVVRKHGNLILHLFGLMTTSGIPGVTMDAVSYVQ 1448
Query: 1394 MSLSGVPGVTS--AAVSYVRXXXXXXXXXXXXXXXXXRLI----------HSSLKS---- 1437
+L +PG T+ AA ++ R + L S
Sbjct: 1449 RAL--LPGQTNPEAAATFARMIESSLKSWFTQFNFFLHNLAQLRFSGEHNEGELLSFIPR 1506
Query: 1438 --NMTQEGRLVSVECLGYEKRYDPEKHYVYALRIYRLGQATPSVLYRSYKHFTELYQKIC 1495
M QEG+L SV+ GY+KRYDPEK+Y+Y L+I R GQ P+ L+RSYK F E YQK+C
Sbjct: 1507 TYTMQQEGQLTSVQVHGYQKRYDPEKYYMYILKIQRKGQTDPTYLFRSYKEFCEFYQKLC 1566
Query: 1496 LHFPLAKV 1503
+HFPLAKV
Sbjct: 1567 IHFPLAKV 1574
>UniRef50_UPI0000DB6BA7 Cluster: PREDICTED: similar to
Phosphotidylinositol 3 kinase 68D CG11621-PA, isoform A;
n=1; Apis mellifera|Rep: PREDICTED: similar to
Phosphotidylinositol 3 kinase 68D CG11621-PA, isoform A -
Apis mellifera
Length = 1681
Score = 913 bits (2259), Expect = 0.0
Identities = 543/1304 (41%), Positives = 737/1304 (56%), Gaps = 103/1304 (7%)
Query: 265 SVRVSVLEAFDPLL--TEQSNPEYA-----VGSECSSSVYEEYDPLDFLYGETE-MRETP 316
+VRVSVLEAFDPLL TE N + S+ + SVY+ +DP D++Y E + P
Sbjct: 209 NVRVSVLEAFDPLLVKTEDQNDNAQGHKDEMQSQVTGSVYDPFDPFDYMYSTNESVNSDP 268
Query: 317 VYGTVGKREXXXXXXXXX-------------XXXXXXXXXXLRSTTNKLYDSIVKIRTRN 363
VY V K R +LY+++ +TR
Sbjct: 269 VYVAVEKSAKSPAVSPAAPPPLPPRNSSAWNTIERRRTSLDRRKRQTRLYENVTVRKTRP 328
Query: 364 Y--DSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKYPPNTSIKILVHHA--HSD 419
D + +AF +M VR +F + + TN GH+I+ YP TSIK++VH SD
Sbjct: 329 SLRDCDLRAFYEMIKSVRSEFPFNNPSTNIGHIISPMMENLYPEGTSIKLVVHPQLIDSD 388
Query: 420 E---PITFTSDVESKVEHVILTVVCSLDEDIREDMSGYMLRVRGAKEYLTPGSSLSEYDY 476
E I+FT DV VEHVIL V CSL+++ ++ Y LRV G EY P ++L++Y+Y
Sbjct: 389 ENTPSISFTCDVNCSVEHVILNVACSLEDEGTVNIEKYCLRVWGLAEYFAPSTTLAQYEY 448
Query: 477 IRECVRLEKDVTLCLHEGRD--STLARTERDDAKDSHLTLDDLFPAQGATPMLSFDNLSI 534
I +C++LEKD+ L + ++ART +DD +D L L+D+ P + P +S+D L I
Sbjct: 449 IHQCIKLEKDIELAILTKAQIKRSIARTLQDDNRDQCLKLEDILPNEPVQP-ISYDTLLI 507
Query: 535 LLETLEGELSR----AIGV-TSAEGSC-----SPKAVFQAVKAICALAGGVETLHVTHTL 584
LLET+E E+ R AI + T+ GS P+ V QA+KA+CAL G +ET +T +
Sbjct: 508 LLETVEKEMERIETAAIQLATTNHGSSLLPQLQPRGVVQAIKAVCALMGNIETFEITEAV 567
Query: 585 NAFAQACTA----QGANNVV--RPEIEREQGAYCSVSLAAGSRRDCVSLQGGRVRDAVXX 638
+ F AC N+ +PEI E G Y V+L D ++ ++R+A+
Sbjct: 568 DNFVNACCQFLPQVHTTNIECKKPEILHEDGDYSVVTLRT-KFPDVIASHCRKIRNAIQD 626
Query: 639 XXXXXXXXXXXDFRLADAHYQAPANPAKAVPAHTISETTLFCIEAVHCLPLCWSHDEYMF 698
DF L ++ + P N + + + +T L + A+H LP W HD+Y+
Sbjct: 627 LVETYCHAFKVDFEL-NSKGEIPTN---ILISSEVLDTILVRVGALHRLPGSWKHDDYII 682
Query: 699 HAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGR 758
AQI+HGTRP+ T ++ + FYPRI+F+ WL + V +PRE+RLVL L+GR
Sbjct: 683 AAQIFHGTRPVGTPVLSEPMAVS-SNFYPRILFNAWLEFRGISVCQVPREARLVLVLYGR 741
Query: 759 TQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPT 818
T + P+ E+ S + + ++ ELGW A+Q FD++G++S G++ L LWP
Sbjct: 742 TLQ------------PTEHESNSSAENIMQKEELGWGAIQFFDYEGIMSQGSFFLSLWPA 789
Query: 819 SCDRRXXXXXXXXXX-XXXXXXVVNIEIPLYAHTGVKWTSGEEDKQKNISLKDLPSFDSL 877
D+R ++ +E+P Y G + E + ++ D F+SL
Sbjct: 790 IADKRLGPAPAPGIHPHGDTHAIIGVELPDY---GGRVLFPTELRDYDVESLD---FNSL 843
Query: 878 DGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQL 937
D +TQ L+ + +Q + + E RE++WEKR YL P ALP VLLAA +W L
Sbjct: 844 DQNTQELLIDITQQTTFSKPLIEEREILWEKRHYLHDKPEALPKVLLAAHSWDWACLPDL 903
Query: 938 IGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
LR+W P+ A+ LLLPCFPD+ VRE A + E+S+D+L LPQL QAL+HETY
Sbjct: 904 HASLRIWNPLPPVQALQLLLPCFPDMKVREMAVGWIRELSNDELVDYLPQLLQALKHETY 963
Query: 998 XXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDAS 1057
+WLL +LP Q+P N + E+ + +S
Sbjct: 964 ETSPLTKFLLERALLSPRVAHHIYWLLTQALPG--QSPQ------NSAETTPEDDKNISS 1015
Query: 1058 MSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXX 1117
R LMLRALL + G+ L + L QQLLVK+L E+A ++K KE
Sbjct: 1016 ARYHRRLQLMLRALLAVIGDALRNSFLTQQLLVKNLYEVAENIKQTKESLRLDTLKVGLQ 1075
Query: 1118 XXXXXXXXQP-TALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGD 1176
T LPL+ K V ++V+SC+YF S TLPLKINFI D+ + A+FKVGD
Sbjct: 1076 NIHCQLMEDDGTCLPLSPSKQVFGINVQSCSYFPSLTLPLKINFISCDDVICSAIFKVGD 1135
Query: 1177 DLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWG 1236
DL+QD L LQ+++IMD LWLK GLDL+MVTF +PT + +GMIE+VT AETLR IQ E+G
Sbjct: 1136 DLQQDMLTLQMVRIMDKLWLKEGLDLKMVTFACVPTGHKRGMIEMVTNAETLRKIQVEFG 1195
Query: 1237 LTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTS 1296
LTGSFKD+PIAEWLAKHNPSELEY+RA +NFTASCAGYSVATY+LGICDRHNDNIMLKTS
Sbjct: 1196 LTGSFKDRPIAEWLAKHNPSELEYERAVENFTASCAGYSVATYILGICDRHNDNIMLKTS 1255
Query: 1297 GHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCC 1356
GHLFHIDFGKFLGDAQMFGNFKR DR PFVLT DM YVINGG++P+ +F HFV+LCC
Sbjct: 1256 GHLFHIDFGKFLGDAQMFGNFKR----DRTPFVLTSDMAYVINGGDKPSAKFHHFVDLCC 1311
Query: 1357 MAFNIVRAHHDHILDLFALPSCDSGGSERTV-AGGRPQMSLSGVPGVTSAAVSYVRXXXX 1415
AFN+VR H + +L LF L + SG S TV A Q +L AA ++ R
Sbjct: 1312 QAFNVVRKHGNLLLHLFGLMT-SSGISGVTVDAVSYVQKALLPEQTNPEAAATFARMIES 1370
Query: 1416 XXXXXXXXXXXX----XRLIHSSLKSN------------MTQEGRLVSVECLGYEKRYDP 1459
+L SS ++ M QEG+L SV+ GY+KRYDP
Sbjct: 1371 SLKSWFTQFNFFLHNLAQLRFSSDHNDGALLSFIPRTYTMQQEGQLTSVQVHGYQKRYDP 1430
Query: 1460 EKHYVYALRIYRLGQATPSVLYRSYKHFTELYQKICLHFPLAKV 1503
EK+Y+Y LRI R G A P+ L+RSYK F E YQK+C+HFPLAK+
Sbjct: 1431 EKYYMYILRIERKGHADPTYLFRSYKEFCEFYQKLCIHFPLAKL 1474
>UniRef50_Q7JNX6 Cluster: Phosphoinositide 3-kinase; n=5; Diptera|Rep:
Phosphoinositide 3-kinase - Drosophila melanogaster
(Fruit fly)
Length = 1876
Score = 753 bits (1863), Expect = 0.0
Identities = 479/1226 (39%), Positives = 640/1226 (52%), Gaps = 124/1226 (10%)
Query: 346 RSTTNKLYDSIVKIRTRNYDSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKYPP 405
R T +LY+ I RT D E F M +VR ++ + D TN GHV+AA Y
Sbjct: 502 RKTCTRLYELISDQRTD--DPELLEFYHMVKEVRARYPHDDAPTNVGHVVAAEFNYHYMM 559
Query: 406 NTSIKILVHHAHSD-------------------EPITFTSDVESKVEHVILTVVCSLDED 446
+TSIK++VH A + P+TFT D++S V V+ + SL+
Sbjct: 560 DTSIKVIVHPALNTLQSTVLAASMGKEQVKGYGMPVTFTCDIDSVVAQVVAQALASLEGQ 619
Query: 447 IREDMSGYMLRVRGAKEYLTPGSSLSEYDYIRECVRLEKDVTL--CLHEGRD-STLARTE 503
++ ++ Y ++ G E+L P S LS+ + + +LEKDV L CL + +ARTE
Sbjct: 620 VKGTVTDYAVKPIGLLEWLAPTSRLSQLECVHNSFQLEKDVHLGLCLSTAANMQAIARTE 679
Query: 504 RDDAKDSHLTLDDLFPAQGATPMLSFDNLSILLETLEGEL----SRAIGVTSAEG-SCSP 558
RDD D+ L + L P + ++++DN+ IL+ETLE E+ S A GV SCS
Sbjct: 680 RDDEHDADLLPEHLLPNE-VVQIVTYDNMMILIETLEMEIDKLESAADGVPGRSVVSCS- 737
Query: 559 KAVFQAVKAICALAGGVETLHVTHTLNAFAQACTAQG---ANNVVRPEIEREQGAYCSVS 615
V QAVKAICAL G ++T+ + + + C + + PEI + G Y V
Sbjct: 738 -GVVQAVKAICALLGSIDTMEIARCVADLKRICEVEQKKYSTGASNPEIVSDYGDYAQVV 796
Query: 616 LAAGSRRDCVSLQGGRVRDAVXXXXXXXXXXXXXDFRLADAHYQAPANPAKAVPAHTISE 675
L S + + ++ +RDAV FR+A + + P +P +S+
Sbjct: 797 LRPRSMLEQIKVKCNELRDAVQELVELYANV----FRVAFS-VKTPDYSTTPIPISCVSK 851
Query: 676 TTLFCIEAVHCLPLCWSHDEYMFHAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWL 735
+ CI +H W D+Y QI +GTR L S GG +PR+ F WL
Sbjct: 852 PIVVCISCLHRPLPNWKFDDYSLCVQIVYGTRLLSKPNVLTCSNDTSGGLFPRLNFSAWL 911
Query: 736 NLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWA 795
+ P+ TLPRE+RL L+G+ Q +E P A+ +G+ ELGW
Sbjct: 912 TFDQHPICTLPREARLTFVLYGK-------QAASEGEP----NADQNGERRQVTTELGWC 960
Query: 796 ALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXX-VVNIEIPLYAHTGVK 854
++QLFDF ++ G Y+L LWP D+ V++IE+P Y ++
Sbjct: 961 SIQLFDFKRVMICGPYLLSLWPPMTDKMLGPAPARGCHPQPDFCPVLSIEVPPYGGR-IE 1019
Query: 855 WTSGEEDKQKNISLKDLPSFD--SLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYL 912
+ +E K P +D SLD + Q +LL E G TE REV WEKR YL
Sbjct: 1020 FPEHQEVP------KPAPHYDFASLDANLQEELLDTAELG--YTGATERREVFWEKRLYL 1071
Query: 913 VQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKL 972
P ALP VL AA +W + L LL W SPL ++ LLLP +PD VRE A +
Sbjct: 1072 QSYPNALPKVLHAAHSWDYANLIDLHALLHSWAPLSPLQSLELLLPRYPDAKVREKAVEW 1131
Query: 973 LNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIP 1032
+++M +D L LPQL Q+L+H+TY +WLLVHSLP+
Sbjct: 1132 ISKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLSKCLESPRFAHHMYWLLVHSLPD-- 1189
Query: 1033 QAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKS 1092
PH ++ E+ T R +MLRAL+ ICGE + + + Q + +
Sbjct: 1190 -DPHNSIGAAMVDQEYDESQVTQVRYYR--RNKMMLRALMAICGEKMLQRFMYQHRMCQK 1246
Query: 1093 LCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSN 1152
L +A SVK AKE QPT LPL V + V++C+YF+SN
Sbjct: 1247 LTTIAESVKEAKESMRQKSLAAGMDEVHQDLLEQPTCLPLGPELEVTGVSVRNCSYFNSN 1306
Query: 1153 TLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPT 1212
TLPLKINF+G D +PA+FK GDDL+QD L +Q+I+IM+ +WL LDL+MVTF +PT
Sbjct: 1307 TLPLKINFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTFNCVPT 1366
Query: 1213 SNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCA 1272
GMIE+V+EAETLR IQ E GLTGSFKD+PIAEWL K NPS LEYQ A NFT SCA
Sbjct: 1367 GYKSGMIELVSEAETLRKIQVECGLTGSFKDRPIAEWLGKQNPSPLEYQSAVRNFTLSCA 1426
Query: 1273 GYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTH 1332
GYSVATY+LGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR DR PFVLT
Sbjct: 1427 GYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR----DRTPFVLTS 1482
Query: 1333 DMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGSERTVAGGRP 1392
DM YVINGG++P+ F +FV+LCC AFNIVR + D +L A
Sbjct: 1483 DMAYVINGGDKPSTDFHYFVDLCCRAFNIVRKNADLLLHTLA------------------ 1524
Query: 1393 QMSLSGVPGVTSAAVSYVRXXXXXXXXXXXXXXXXXRLIHSSLKSNMTQ----------- 1441
M+ +G+PGV S AV YVR ++I SSLKS TQ
Sbjct: 1525 HMATAGMPGVNSNAVQYVRRALLPSQSNPEAAATFAKMIQSSLKSWFTQFNFFLHNLAQM 1584
Query: 1442 -------EGRLVSVECLGYEKRYDP----------EKHY------VYALRIYRLGQATPS 1478
G L+S Y + D +KHY +Y L + R GQ P+
Sbjct: 1585 RFTPDEGSGELLSFVPRKYTMQQDGRLKIVKVVCFQKHYSMEKFYMYILEVTRHGQPDPT 1644
Query: 1479 VLYRSYKHFTELYQKICLHFPLAKVH 1504
L+RSY+ FTE +QK+C+HFPL K+H
Sbjct: 1645 HLFRSYREFTEFHQKLCMHFPLVKLH 1670
Score = 50.8 bits (116), Expect = 3e-04
Identities = 38/96 (39%), Positives = 52/96 (54%), Gaps = 12/96 (12%)
Query: 231 VSIGSNESNDTVGSLPKSMN-LIDFGGRNPNGSQGSVRVSVLEAFDPLLTEQSNPEYAVG 289
VS S+ N+ S+P+ N LID + + RVSVLEAFDPLL + + + A
Sbjct: 316 VSSSSHTGNNGHSSVPRRGNDLIDLNHEDYS------RVSVLEAFDPLLNDNTGNDTA-- 367
Query: 290 SECSSSVYEEYDPLDFLY-GETEMR-ETPVYGTVGK 323
S+S Y EYDP DFLY G+ + P+Y V +
Sbjct: 368 -SDSTSYYAEYDPFDFLYSGDAATQYSDPMYEAVNR 402
>UniRef50_UPI0000D572A6 Cluster: PREDICTED: similar to CG11621-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG11621-PA, isoform A - Tribolium castaneum
Length = 1509
Score = 753 bits (1862), Expect = 0.0
Identities = 481/1226 (39%), Positives = 647/1226 (52%), Gaps = 129/1226 (10%)
Query: 247 KSMNLIDFGGRNPNGSQGSVRVSVLEAFDPLLTEQS-------NPEYAV-GSECSSSVYE 298
+S +LID G + N SVRVS+L+ FDP+L+ +P++A G+ SVY+
Sbjct: 65 RSHDLIDLGHEDTN----SVRVSILQEFDPILSSGDFPVSRTVSPDFADDGASVCGSVYD 120
Query: 299 EYDPLDFLYGE-TEMRETPVYGTVGKREXXXXXXXXXXXXXXXXXXXLRSTTNKL--YDS 355
+YDP D G P+Y K + T+KL D
Sbjct: 121 DYDPYDIYTGSGNNSMSDPLYAAPAKSPPPLPPREYLA----------KKMTDKLNLLDG 170
Query: 356 IVKIRTRNY---DSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKYPPNTSIKIL 412
IV++ +N DS+ KAF M VR K+ + D TN G VI+ +Y TSIK+
Sbjct: 171 IVRVDEKNNAQRDSDLKAFYHMVKSVRGKYRFNDIDTNMGLVISPMVDYQYKEGTSIKLC 230
Query: 413 VHH----AHSDEPITFTSDVESKVEHVILTVVCSLDEDIREDMSGYMLRVRGAKEYLTPG 468
V+ A +PI FT DV +EHV L + C LD ++ Y L+V G EYL P
Sbjct: 231 VYPDFEGADITKPINFTCDVNCSIEHVTLQLTCDLDAPSKDK---YTLKVWGCNEYLVPT 287
Query: 469 SSLSEYDYIRECVRLEKDVTLCLHEGR--DSTLARTERDDAKDSHLTLDDLFPAQGATPM 526
+ LS+Y+Y+ C++LE+D+ L L D + ART +DD +D LT +D+ P
Sbjct: 288 TFLSDYEYVHNCIKLEEDILLTLIPDSKVDKSFARTPQDDNRDRDLTYEDVIPTD-CNIH 346
Query: 527 LSFDNLSILLETLEGELSRAIGVTSAEGSCS---------PKAVFQAVKAICALAGGVET 577
L++DNL ILLET+E E+ + C+ P V Q+ K + L G + T
Sbjct: 347 LTYDNLVILLETVENEMKKLEDAALQMQKCNNPVTMPALQPLKVIQSAKCVINLMGNLAT 406
Query: 578 LHVTHTLNAFAQACTAQGANNVVRPEIEREQGAYCSVSLAAGSRRDCVSLQGGRVRDAVX 637
L +T ++ + T N P + + C+ R+R A+
Sbjct: 407 LDLTSAVDDLQRITT-----NFQTPLLNDNISSTCN-----------------RIRLAIQ 444
Query: 638 XXXXXXXXXXXXDFRLADAHYQAPANPAKAVPAHTISETTLFCIEAVHCLPLCWSHDEYM 697
DF + + P K V + E+ + + A++ + W HD +M
Sbjct: 445 NLIEMYSQAFKVDFEVRKT---TTSEPVKYVS--DVMESLVIRVCAIYRPNVEWKHDSFM 499
Query: 698 FHAQIYHGTRPLKTLRFTQAS-KIECGGFYP-RIIFDTWLNLEDLPVNTLPRESRLVLTL 755
AQIYHGTRP+ +Q K E +P RII D W ++ D+ ++ L RESRL L +
Sbjct: 500 VAAQIYHGTRPMGHPVLSQPCVKTESDHKWPARIIIDHWFDMIDIHISALARESRLKLVI 559
Query: 756 HGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPL 815
+GRT D +N P +QE E+GWA++Q F +DG + GN +L +
Sbjct: 560 YGRTMEPSDDA---QNEPKYTQE------------EIGWASVQFFTYDGTMVQGNIILSI 604
Query: 816 WPTSCDRRXXXXXXXXXXXXXXXXVVNIEIPLYAHTGVKWTSGEEDKQKNISLKDLPSFD 875
WP +++I+I H ++ D +N+ D F
Sbjct: 605 WPPDSQFLHGAPPAFGTHPTPDHPMMDIQIA-GGHPKTEFPKVPPDLIRNVVKGD---FQ 660
Query: 876 SLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHRE 935
SLD TQ QL+ + EQ ++P + REV+WEKR YL IP ALP VLLAA +W
Sbjct: 661 SLDRSTQQQLIDICEQDMLCKLPPQLREVLWEKRHYLYHIPEALPKVLLAAHSWEYALLP 720
Query: 936 QLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
L G+L W+ P+ A+ LLLP FPD+ VR+ A + +N +++D L LPQL ALRHE
Sbjct: 721 DLHGMLYAWQPLRPIQALQLLLPTFPDLEVRKIAIRWINGLTNDQLVDYLPQLVVALRHE 780
Query: 996 TYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETD 1055
Y FWLL H+LP G N ++++S++ T
Sbjct: 781 IYENSPLAQFLLDRSLRAPRLAHHLFWLLSHTLP-----------GSNPQNSSSDDI-TV 828
Query: 1056 ASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXX 1115
A R LMLRALL ICG++L L QQLLVK L ++A +VK KE
Sbjct: 829 AEGRHHRRLKLMLRALLAICGDSLRSCFLSQQLLVKELNDLAETVKKTKESQRTQVLQNR 888
Query: 1116 XXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVG 1175
PT+LPL+ V +++KSC Y+ SNTLPLKI+F+ VI A++KVG
Sbjct: 889 LRLVDAHLSDNPTSLPLSPTLKVSGVEIKSCFYYPSNTLPLKISFVDGRGTVISAIYKVG 948
Query: 1176 DDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEW 1235
DDL+QD L LQ++++MD LWL GLDL+MV+F +PT +GMIE+VT+AETLR IQ E
Sbjct: 949 DDLQQDMLTLQMVRLMDKLWLNQGLDLKMVSFVCVPTGKKRGMIEMVTKAETLRKIQVEH 1008
Query: 1236 GLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT 1295
GLTGSFKDKPIAEWLAKHNPSELEYQRA +NFTASCAGY V TY+LGICDRHNDNIMLKT
Sbjct: 1009 GLTGSFKDKPIAEWLAKHNPSELEYQRAVENFTASCAGYCVVTYILGICDRHNDNIMLKT 1068
Query: 1296 SGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELC 1355
SGHLFHIDFGKFLGDAQMFGNFKR DRAPFVLT DM YVINGG+RP+++F FV+LC
Sbjct: 1069 SGHLFHIDFGKFLGDAQMFGNFKR----DRAPFVLTSDMAYVINGGDRPSEKFHKFVDLC 1124
Query: 1356 CMAFNIVRAHHDHILDLFALPSCDSGGSERTVAGGRPQMSLSGVPGVTSAAVSYVRXXXX 1415
C AFNI+R + + L LF L M+ SG+ G+T +VSY+
Sbjct: 1125 CQAFNIIRDNANLFLYLFTL------------------MASSGICGMTPESVSYLHKALL 1166
Query: 1416 XXXXXXXXXXXXXRLIHSSLKSNMTQ 1441
RLI SSLKS TQ
Sbjct: 1167 PHMSNPEAAAYFARLIESSLKSWFTQ 1192
Score = 86.6 bits (205), Expect = 5e-15
Identities = 34/67 (50%), Positives = 52/67 (77%)
Query: 1438 NMTQEGRLVSVECLGYEKRYDPEKHYVYALRIYRLGQATPSVLYRSYKHFTELYQKICLH 1497
+M +G+LV V+ + Y+KRYDP+K+YVY LR+ R G + ++R+YK F EL+QK+C++
Sbjct: 1223 SMATDGKLVHVQVVSYKKRYDPDKYYVYVLRVTREGDKSDMEIHRTYKEFCELHQKLCIY 1282
Query: 1498 FPLAKVH 1504
FPLAK+H
Sbjct: 1283 FPLAKLH 1289
>UniRef50_Q29DX8 Cluster: GA11104-PA; n=3; Diptera|Rep: GA11104-PA -
Drosophila pseudoobscura (Fruit fly)
Length = 1868
Score = 750 bits (1855), Expect = 0.0
Identities = 475/1231 (38%), Positives = 640/1231 (51%), Gaps = 127/1231 (10%)
Query: 346 RSTTNKLYDSIVKIRTRNYDSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKYPP 405
R T +LY+ I RT D E F M +R ++ + D TN GHV+AA Y
Sbjct: 487 RKTCTRLYELISDQRTD--DPELLEFYHMVKQLRSRYPHDDAPTNVGHVVAAEFNYHYMM 544
Query: 406 NTSIKILVH--------HAHSDE-------------PITFTSDVESKVEHVILTVVCSLD 444
+TSIK++VH HA S P+TFT D++S V V+ + SL+
Sbjct: 545 DTSIKVIVHPALNTLQQHALSTSAAAAEGQVKGYGTPVTFTCDIDSVVAQVVAQALASLE 604
Query: 445 EDIREDMSGYMLRVRGAKEYLTPGSSLSEYDYIRECVRLEKDVTL--CLHEGRD-STLAR 501
++ ++ Y+++ G E+L P S LS+ + + +LEKDV L CL + +AR
Sbjct: 605 GQVKGSVTDYVVKPIGLLEWLAPTSRLSQLESVHNSFQLEKDVHLGLCLSTASNMQAIAR 664
Query: 502 TERDDAKDSHLTLDDLFPAQGATPMLSFDNLSILLETLEGELSRAIGVT------SAEGS 555
+ERDD D+ L + LFP + P++++DN+ IL+ETLE E+ + S
Sbjct: 665 SERDDVNDADLQPEQLFPNE-VVPIVTYDNMMILIETLEMEIDKLESAADPPPPASGRSV 723
Query: 556 CSPKAVFQAVKAICALAGGVETLHVTHTLNAFAQACT-AQ----GANNVVRPEIEREQGA 610
S V QAVKAICAL G ++TL + + + C AQ + PEI + G
Sbjct: 724 VSCSGVVQAVKAICALLGSIDTLDIARCVADLKRVCEDAQTKYAAGSGASNPEIVSDYGD 783
Query: 611 YCSVSLAAGSRRDCVSLQGGRVRDAVXXXXXXXXXXXXXDFRLADAHYQAPANPAKAVPA 670
Y V++ S + + ++ +RDAV F + Y +P
Sbjct: 784 YAQVTMRPRSLLEQIKVKCNSLRDAVQELVELYANVFRVAFSVKSLDYATTP-----IPI 838
Query: 671 HTISETTLFCIEAVHCLPLCWSHDEYMFHAQIYHGTRPLKTLRFTQASKIECGGFYPRII 730
+S+ + I +H P W +D+Y Q+ +GTR L S GG +PR+
Sbjct: 839 SCVSKPIVVSINCLHRPPPNWKYDDYSLCVQLVYGTRLLSKPNVLSCSNDTSGGLFPRLN 898
Query: 731 FDTWLNLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQV 790
F WL E P+ TLPRE+R+ L+G+ Q +EN P S E +G+
Sbjct: 899 FSAWLTFEQHPICTLPREARVTFVLYGK-------QAASENEPNS----EPNGERRQVTT 947
Query: 791 ELGWAALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXX-VVNIEIPLYA 849
ELGW ++QLFDF + G Y+L +WP + D+ V++IE+P Y
Sbjct: 948 ELGWCSIQLFDFKRAMICGPYLLSVWPPTTDKMLGPAPARGCHPHPDFCPVLSIEVPPYG 1007
Query: 850 HTGVKWTSGEEDKQKNISLKDLPSFD--SLDGHTQSQLLHLIEQGAYQRMPTECREVMWE 907
+++ +E K P +D SLD + Q +LL E G TE REV WE
Sbjct: 1008 GR-IEFPEHQEVP------KPAPHYDFASLDANLQEELLDTAELG--YTGATERREVFWE 1058
Query: 908 KRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRE 967
KR YL P ALP VL AA +W + L LL W SPL A+ LLLP +PD VRE
Sbjct: 1059 KRLYLQNYPNALPKVLHAAHSWDYANLIDLHALLHSWAPLSPLQALELLLPRYPDAKVRE 1118
Query: 968 TAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHS 1027
A + +++M +D L LPQL Q+L+H+TY +WLLVHS
Sbjct: 1119 KAVEWISKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLAKCLESPRFAHHMYWLLVHS 1178
Query: 1028 LPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQ 1087
LP+ PH ++ E T A R +MLRAL+ ICGE + + + Q
Sbjct: 1179 LPD---DPHNSIGAAMVDQEYDECQITQARYYR--RSKMMLRALMDICGEKMLQRFMYQH 1233
Query: 1088 LLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCT 1147
+ + L +A SVK +KE +PT LPL V + V++C+
Sbjct: 1234 RMCQKLTTIAESVKESKESMRQKSLAAGMDEVHQDLLDKPTCLPLGPELEVTGVAVRNCS 1293
Query: 1148 YFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTF 1207
YF+SNTLPLKI F+G D +PA+FK GDDL+QD L +Q+I+IM+ +WL LDL+MVTF
Sbjct: 1294 YFNSNTLPLKITFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTF 1353
Query: 1208 QALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNF 1267
+PT GMIE+V+EAETLR IQ E GLTGSFKD+PIAEWL K NPS LEYQ A NF
Sbjct: 1354 NCVPTGYKSGMIELVSEAETLRKIQVECGLTGSFKDRPIAEWLGKQNPSPLEYQSAVRNF 1413
Query: 1268 TASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAP 1327
T SCAGYSVATY+LGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR DR P
Sbjct: 1414 TLSCAGYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR----DRTP 1469
Query: 1328 FVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGSERTV 1387
FVLT DM YVINGG++P+ F +FV+LCC AFNIVR + D +L A
Sbjct: 1470 FVLTSDMAYVINGGDKPSTDFHYFVDLCCRAFNIVRKNADLLLHTLA------------- 1516
Query: 1388 AGGRPQMSLSGVPGVTSAAVSYVRXXXXXXXXXXXXXXXXXRLIHSSLKSNMTQ------ 1441
M+ +G+PGV S AV+YVR ++I SSLKS TQ
Sbjct: 1517 -----HMATAGMPGVNSNAVTYVRRALLPSQSNPEAAATFAKMIQSSLKSWFTQFNFFLH 1571
Query: 1442 ------------EGRLVSVECLGYEKRYDP----------EKHY------VYALRIYRLG 1473
G L+S Y + D +KHY +Y L++ R G
Sbjct: 1572 NLAQMRFTADEGTGELLSFVPRKYTMQQDGRLKIVKVVRFQKHYSMEKFYMYILQVTRHG 1631
Query: 1474 QATPSVLYRSYKHFTELYQKICLHFPLAKVH 1504
Q P+ L+RSY+ FTE +QK+C+HFPL K+H
Sbjct: 1632 QPDPTHLFRSYREFTEFHQKLCMHFPLVKLH 1662
Score = 48.4 bits (110), Expect = 0.001
Identities = 30/60 (50%), Positives = 36/60 (60%), Gaps = 7/60 (11%)
Query: 267 RVSVLEAFDPLLTEQSNPEYAVGSECSSSVYEEYDPLDFLY---GETEMRETPVYGTVGK 323
RVSVLEAFDPLL E + A S+S Y EYDP DFLY G T+ + P+Y V +
Sbjct: 327 RVSVLEAFDPLLNENIGNDSA---SDSTSYYAEYDPFDFLYSGDGGTQYSD-PMYEAVNR 382
>UniRef50_O00443 Cluster: Phosphatidylinositol-4-phosphate 3-kinase C2
domain-containing alpha polypeptide; n=28;
Euteleostomi|Rep: Phosphatidylinositol-4-phosphate
3-kinase C2 domain-containing alpha polypeptide - Homo
sapiens (Human)
Length = 1686
Score = 542 bits (1337), Expect = e-152
Identities = 382/1168 (32%), Positives = 575/1168 (49%), Gaps = 92/1168 (7%)
Query: 365 DSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKY--PPNTSIKILVHHAHSDEPI 422
+ E AF + ++ KF YT+ RTNPG++++ + + N S+K+ + P+
Sbjct: 378 NEEMAAFCRSITKLKTKFPYTNHRTNPGYLLSPVTAQRNICGENASVKVSIDIEGFQLPV 437
Query: 423 TFTSDVESKVEHVILTVVCSLDEDIRE-DMSGYMLRVRGAKEYLTPGSSLSEYDYIRECV 481
TFT DV S VE +I+ +C + +D+ + D+ Y+L+V G +E L L +++I+ C
Sbjct: 438 TFTCDVSSTVEIIIMQALCWVHDDLNQVDVGSYVLKVCGQEEVLQNNHCLGSHEHIQNCR 497
Query: 482 RLEKDVTLCL--HEGRDSTLARTERDDAKDSHLTLDDLFPAQGATPMLSFDNLSILLETL 539
+ + ++ L L LART DD L + ++ + LL++
Sbjct: 498 KWDTEIRLQLLTFSAMCQNLARTAEDDETPVDLNKHLYQIEKPCKEAMTRHPVEELLDSY 557
Query: 540 EGELSRAIGVTSAEGSCSPKAVFQAVKAICALAGGVETLHVTHTLNAFAQACTAQGANNV 599
++ A+ + + + V +AV+ IC+ GVETL +T ++ +A N+
Sbjct: 558 HNQVELALQIENQHRAVDQ--VIKAVRKICSALDGVETLAITESVKKLKRAV------NL 609
Query: 600 VRPEIEREQGAYCSVSLAAGSRRDCVSLQGGRVRDAVXXXXXXXXXXXXXDFRLADAHYQ 659
R + + + S R ++ + V+ ++ +
Sbjct: 610 PRSKTADVTSLFGGEDTSRSSTRGSLNPENP-VQVSINQLTAAIYDLLRLHANSGRSPTD 668
Query: 660 APANPAKAVPAHTISETTLFCIEAVHCLPLCW--SHDEYMFHAQIYHGTRPLKTLRFTQA 717
+ A T +E F I A H + W ++++Y + H + L + Q+
Sbjct: 669 CAQSSKSVKEAWTTTEQLQFTIFAAHGISSNWVSNYEKYYLICSLSHNGKDL--FKPIQS 726
Query: 718 SKIEC-GGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSS 776
K+ F+ I +D L + + ++ LP ES L LTL G ++ S P+ N
Sbjct: 727 KKVGTYKNFFYLIKWDE-LIIFPIQISQLPLESVLHLTLFGILNQSSGSS-PDSNKQRKG 784
Query: 777 QEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXX 836
EA LG +L LFDF L+ G +L LW TS
Sbjct: 785 PEA------------LGKVSLPLFDFKRFLTCGTKLLYLW-TSSHTNSVPGTVTKKGYVM 831
Query: 837 XXXVVNIEIPLYAHTGVKWTSGEEDKQKNISLKDLPSFDSLDGHTQSQLLHLIEQGAYQR 896
V+ ++ P A + +T+ + D+ S+ + ++L+ + +LL ++ + +
Sbjct: 832 ERIVLQVDFPSPAFD-IIYTTPQVDR----SIIQQHNLETLENDIKGKLLDILHKDSSLG 886
Query: 897 MPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLL 956
+ E + +WEKR Y + P LP +L +A NW + + LL W PL A+ LL
Sbjct: 887 LSKEDKAFLWEKRYYCFKHPNCLPKILASAPNWKWVNLAKTYSLLHQWPALYPLIALELL 946
Query: 957 LPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXX 1016
F D VR A + +SDD+L +LPQ QAL++E Y
Sbjct: 947 DSKFADQEVRSLAVTWIEAISDDELTDLLPQFVQALKYEIYLNSSLVQ------------ 994
Query: 1017 XXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICG 1076
+LL +L NI A + +L L+D A D S RY +L ALL + G
Sbjct: 995 -----FLLSRALGNIQIAHNLYWL---LKD-----ALHDVQFST--RYEHVLGALLSVGG 1039
Query: 1077 ENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHK 1136
+ L + LL+Q LV+ L +A V+ A LPL
Sbjct: 1040 KRLREELLKQTKLVQLLGGVAEKVRQASGSARQVVLQRSMERVQSFFQKNKCRLPLKPSL 1099
Query: 1137 YVHDLDVKSCTYFSSNTLPLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVIKIMDTL 1194
+L++KSC++FSSN +PLK+ + D I MFKVG+DLRQD L LQ+IKIMD +
Sbjct: 1100 VAKELNIKSCSFFSSNAVPLKVTMVNADPMGEEINVMFKVGEDLRQDMLALQMIKIMDKI 1159
Query: 1195 WLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHN 1254
WLK GLDLRMV F+ L T +GM+E+V ++TLR IQ E+G+TGSFKDKP+AEWL K+N
Sbjct: 1160 WLKEGLDLRMVIFKCLSTGRDRGMVELVPASDTLRKIQVEYGVTGSFKDKPLAEWLRKYN 1219
Query: 1255 PSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMF 1314
PSE EY++A +NF SCAG VATY+LGICDRHNDNIML+++GH+FHIDFGKFLG AQMF
Sbjct: 1220 PSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIMLRSTGHMFHIDFGKFLGHAQMF 1279
Query: 1315 GNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFA 1374
G+FKR DRAPFVLT DM YVINGGE+PT RFQ FV+LCC A+N++R + L+L +
Sbjct: 1280 GSFKR----DRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAYNLIRKQTNLFLNLLS 1335
Query: 1375 LPSCDSGGSERTVAGGRPQMSLSGVPGVT--SAAVSYVRXXXXXXXXXXX----XXXXXX 1428
L SG E T + + P T A + + R
Sbjct: 1336 L-MIPSGLPELTSIQDLKYVRDALQPQTTDAEATIFFTRLIESSLGSIATKFNFFIHNLA 1394
Query: 1429 RLIHSSLKSN-------------MTQEGRLVSVECLGYEKRYDPEKHYVYALRIYRLGQA 1475
+L S L SN Q+GR+ V Y K+Y+P+KHY+Y +RI R GQ
Sbjct: 1395 QLRFSGLPSNDEPILSFSPKTYSFRQDGRIKEVSVFTYHKKYNPDKHYIYVVRILREGQI 1454
Query: 1476 TPSVLYRSYKHFTELYQKICLHFPLAKV 1503
PS ++R++ F EL+ K+ + FPL K+
Sbjct: 1455 EPSFVFRTFDEFQELHNKLSIIFPLWKL 1482
>UniRef50_Q1L913 Cluster: Novel protein similar to vertebrate
phosphoinositide-3-kinase, class 2, alpha polypeptide;
n=3; Danio rerio|Rep: Novel protein similar to vertebrate
phosphoinositide-3-kinase, class 2, alpha polypeptide -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1725
Score = 499 bits (1230), Expect = e-139
Identities = 387/1224 (31%), Positives = 588/1224 (48%), Gaps = 128/1224 (10%)
Query: 346 RSTTNKL--YDSIVKIRTRNYDSEHKAFLKMALDVRKKFVYTDERTNPGHV----IAARS 399
+ +TN L Y ++ + +N E AF + +R KF + D TNPG+V I R
Sbjct: 357 KGSTNVLSKYSALQEKEAQNL--EVVAFCEDISKLRSKFPHDDLSTNPGYVLSPVITQRD 414
Query: 400 GGKYPPNTSIKILVHHAHSDEPITFTSDVESKVEHVILTVVCSLDEDIRE-DMSGYMLRV 458
G S+K+ + + S +P+TFT DV S V+ +I+ +C + +D+ + D++ Y+L+V
Sbjct: 415 AGG-DNGGSVKVSIEISDSQQPVTFTCDVTSPVDLLIMQALCWVHDDLNQVDINSYVLKV 473
Query: 459 RGAKEYLTPGSSLSEYDYIRECVRLEKDVTLCLH--EGRDSTLARTERDDAKDSHLTLDD 516
G +E L SL ++Y++ C + E ++ L L LART DD L
Sbjct: 474 CGQEEVLQNKHSLGSHEYVQNCRKWESEIKLQLLFLSTMRRDLARTAEDDISPIDLEKYL 533
Query: 517 LFPAQGATPMLSFDNLSILLETLEGELSRAIGVTSAEGSCSPKAVFQAVKAICALAGGVE 576
+ ++ + L+ LE +++ + + + V Q+VK +C VE
Sbjct: 534 GLVERPFKEAVTREGLAEYLEGFHKQVNLCLQNENNQYKTVDNVV-QSVKNLCCALDEVE 592
Query: 577 TLHVTHTLNAFAQACTAQGANNVVRPEIEREQGAY---CSVSLAAGSRRDCVSLQGGRVR 633
T +T + ++ + PE + Y C + A + S GG
Sbjct: 593 TPAITDAVKRLKRSVNLPRTRS---PESKMFFYCYMCACFIKHYAELQAGATS-SGGSAN 648
Query: 634 DAVXXXXXXXXXXXXXDFRLADAHYQA--PANPAKAVPAHTISE--------TT---LFC 680
+ LA + Q+ P +P + H E TT F
Sbjct: 649 GYSSPVEESLAVLTDAVYELAKLYLQSFCPISPGFMIEEHKEDERDSKEASGTTEHLQFT 708
Query: 681 IEAVHCLPLCW--SHDEYMFHAQIYHGTRPLKTLRFTQASKIEC-GGFYPRIIFDTWLNL 737
+ AVH +P W S ++Y + H R L + Q+ K+ F+ I +D +N
Sbjct: 709 LFAVHGIPATWVSSFEKYYLMCALTHNNRNL--FKPVQSKKVGTYKSFFYHIKWDELINF 766
Query: 738 EDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAAL 797
+ V+ LP E+ L L+L+G + SQ+ N NSP S+++ + G L LG ++
Sbjct: 767 P-ISVSLLPLEAMLSLSLYG-----VLSQNAN-NSPDSNKQRK--GPEL-----LGKVSM 812
Query: 798 QLFDFD---------------GMLSSGNYVLPLW--PTSCDRRXXXXXXXXXXXXXXXXV 840
LFDF G+LS G+ +L LW P + +
Sbjct: 813 PLFDFRRQVINSTSNTQELPLGVLSRGSKLLSLWTSPQALQPGAAGKGRNPTEKIILQVL 872
Query: 841 VNIEIPLYAHTGVKWTSGEEDKQKNISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTE 900
++ P A V + +E+ N S D LD +S++ L + + +
Sbjct: 873 SFVDFPSPA-VDVLYVGPQENGCPNPQ-----SLDPLDQDDRSEIEKLCARASTFGLSRA 926
Query: 901 CREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCF 960
R+++W++R Y + +LP +L +A +W ++ LL W SP++A+ LL F
Sbjct: 927 DRQLLWDQRYYCREYEYSLPKILASAPSWDWGSMGEIHALLHHWPALSPVSALELLESKF 986
Query: 961 PDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXX 1020
D VR+ A + SDD+L LPQL QA++ E +
Sbjct: 987 ADTEVRKVAVSWIQSSSDDELADYLPQLVQAVKFECHLNNALVK---------------- 1030
Query: 1021 FWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLN 1080
+LL +L N+ A + +L L D + A RY +L LL +CG L
Sbjct: 1031 -FLLSRALGNVNIAHYLYWL---LRDAVQDPA-------FGQRYERILCVLLCLCGTGLR 1079
Query: 1081 KTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHD 1140
L +Q LV+ L +A V+ A LP++ +
Sbjct: 1080 AELEKQTRLVQLLGALAEKVRQASSSTRQVVLLEGLERVQSFFQKNSCRLPISPSLVAKE 1139
Query: 1141 LDVKSCTYFSSNTLPLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKA 1198
L++K C++F+SN +PLKI + D I MFKVG+DLRQD L LQ+I+IMD +WL+
Sbjct: 1140 LNIKVCSFFNSNAVPLKIALVNADPLGDEINVMFKVGEDLRQDMLALQMIRIMDRIWLQE 1199
Query: 1199 GLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSEL 1258
GLDLR+V F+ + T KGM+E+V +ETLR IQ E+G+TGSFKDKP+AEWL K+NP+E
Sbjct: 1200 GLDLRIVNFKCISTGKDKGMVELVPSSETLRKIQVEYGVTGSFKDKPLAEWLRKYNPAED 1259
Query: 1259 EYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFK 1318
EY++A +NF +CAG VATY+LGICDRHNDNIML+++GH+FHIDFGKFLG AQM G+FK
Sbjct: 1260 EYEKASENFIYTCAGCCVATYILGICDRHNDNIMLRSTGHMFHIDFGKFLGHAQMIGSFK 1319
Query: 1319 RLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSC 1378
R DRAPFVLT DM YVINGGERPT RFQ FV+LC A+N++R H + L+L +L +
Sbjct: 1320 R----DRAPFVLTSDMAYVINGGERPTSRFQLFVDLCSQAYNLIRKHSNLFLNLLSLMT- 1374
Query: 1379 DSGGSERTVAGGRPQMSLSGVPGVT--SAAVSYVRXXXXXXXXXXX----XXXXXXRLIH 1432
SG E T + + P T A + + R +L
Sbjct: 1375 QSGLPELTGVQDLKYVYDALQPQTTDAEATIFFTRLIESSLGSVATKFNFFIHNLAQLRF 1434
Query: 1433 SSLKSN-------------MTQEGRLVSVECLGYEKRYDPEKHYVYALRIYRLGQATPSV 1479
S L SN M Q+G++ ++KRY+P+KHY Y +RI R GQ+ P
Sbjct: 1435 SGLPSNDEPILSFAPRTYTMKQDGKIRDASVFSFQKRYNPDKHYTYVIRILREGQSEPQF 1494
Query: 1480 LYRSYKHFTELYQKICLHFPLAKV 1503
++R++ F EL+ K+ + F L K+
Sbjct: 1495 VFRTFDEFQELHNKLTILFQLWKL 1518
>UniRef50_O00750 Cluster: Phosphatidylinositol-4-phosphate 3-kinase C2
domain-containing beta polypeptide; n=35;
Deuterostomia|Rep: Phosphatidylinositol-4-phosphate
3-kinase C2 domain-containing beta polypeptide - Homo
sapiens (Human)
Length = 1634
Score = 475 bits (1170), Expect = e-132
Identities = 364/1163 (31%), Positives = 540/1163 (46%), Gaps = 102/1163 (8%)
Query: 365 DSEHKAFLKMALDVRKKFVYTDERTNPGHVIAA--RSGGKYPPNTSIKILVHHAHSDEPI 422
D E AF M LD+ + + G+V +A S ++K+ V E +
Sbjct: 333 DEEVAAFCHM-LDILRSGSDIQDYFLTGYVWSAVTPSPEHLGDEVNLKVTVLCDRLQEAL 391
Query: 423 TFTSDVESKVEHVILTVVCSLDEDIRE-DMSGYMLRVRGAKEYLTPGSSLSEYDYIRECV 481
TFT + S V+ +I +C +D+R D+ ++L+ G +E+L +L ++YI+ C
Sbjct: 392 TFTCNCSSTVDLLIYQTLCYTHDDLRNVDVGDFVLKPCGLEEFLQNKHALGSHEYIQYCR 451
Query: 482 RLEKDVTLCLHEGR--DSTLARTERDDAKDSHLTLDDLFPAQGATPMLSFDNLSILLETL 539
+ + D+ L L E + S LART DD S L + +S LS+L +T
Sbjct: 452 KFDIDIRLQLMEQKVVRSDLARTVNDDQSPSTLNYLVHLQERPVKQTISRQALSLLFDTY 511
Query: 540 EGELSRAIGVTSAEGSCSPKA--VFQAVKAICALAGGVETLHVTHTLNAFAQACTAQGAN 597
E+ + A+G KA V Q+VKAIC VET +T LN C ++
Sbjct: 512 HNEVDAFL---LADGDFPLKADRVVQSVKAICNALAAVETPEITSALNQLPP-CPSR--- 564
Query: 598 NVVRPEIEREQGAYCSVSLAAGSRRDCVSLQGGRVRDAVXXXXXXXXXXXXXDFRLADAH 657
++P+I+++ SV +R V + D V DF+ A
Sbjct: 565 --MQPKIQKDP----SVLAVRENREKVVEALTAAILDLVELYCNTFNA----DFQTAVPG 614
Query: 658 YQAPANPAKAVPAHTISETTLFCIEAVHCLPLCW--SHDEYMFHAQIYHGTRPLKTLRFT 715
+ +A H + + F + A H +P+ W S++++ + HG + L + T
Sbjct: 615 SRKHDLVQEA--CH-FARSLAFTVYATHRIPIIWATSYEDFYLSCSLSHGGKELCSPLQT 671
Query: 716 QASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPS 775
+ + F+ I++D + + VN LPRE+ L TL+ P S
Sbjct: 672 RRAHFSKYLFH-LIVWDQQICFP-VQVNRLPRETLLCATLYALPIPP----------PGS 719
Query: 776 SQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXX 835
S EA V LGW LF+F +L+ G +L LWP +
Sbjct: 720 SSEANKQRRV---PEALGWVTTPLFNFRQVLTCGRKLLGLWPAT-QENPSARWSAPNFHQ 775
Query: 836 XXXXVVNIEIPLYAHTGVKWTSGEEDKQKNISLKDLPSFDSLDGHTQSQLLHLIEQGAYQ 895
++ I+ P A +K+TS DK F SL Q +L ++++ +
Sbjct: 776 PDSVILQIDFPTSAFD-IKFTSPPGDK-----FSPRYEFGSLREEDQRKLKDIMQKESLY 829
Query: 896 RMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHL 955
+ ++ +WEKR Y +LPLVL +A +W + LL+ W + +A+ L
Sbjct: 830 WLTDADKKRLWEKRYYCHSEVSSLPLVLASAPSWEWACLPDIYVLLKQWTHMNHQDALGL 889
Query: 956 LLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXX 1015
L FPD VR A + + +SD +L LPQL QAL++E Y
Sbjct: 890 LHATFPDQEVRRMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLR 949
Query: 1016 XXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVIC 1075
FWL L+D ++ S RY +L ALL C
Sbjct: 950 VTHYFFWL--------------------LKDGLKDS-------QFSIRYQYLLAALLCCC 982
Query: 1076 GENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTA-LPLAL 1134
G+ L + RQ LV +L ++A V+ A + LPL+
Sbjct: 983 GKGLREEFNRQCWLVNALAKLAQQVREAAPSARQGILRTGLEEVKQFFALNGSCRLPLSP 1042
Query: 1135 HKYVHDLDVKSCTYFSSNTLPLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVIKIMD 1192
V + + C+YF+SN +PLK++F D I +FK GDDLRQD L LQ+I+IM
Sbjct: 1043 SLLVKGIVPRDCSYFNSNAVPLKLSFQNVDPLGENIRVIFKCGDDLRQDMLTLQMIRIMS 1102
Query: 1193 TLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAK 1252
+W++ GLD+RMV F+ T +GM+E++ AETLR IQ E G+TGSFKD+P+A+WL K
Sbjct: 1103 KIWVQEGLDMRMVIFRCFSTGRGRGMVEMIPNAETLRKIQVEHGVTGSFKDRPLADWLQK 1162
Query: 1253 HNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQ 1312
HNP E EY++A +NF SCAG VATY+LGICDRHNDNIMLKT+GH+FHIDFG+FLG AQ
Sbjct: 1163 HNPGEDEYEKAVENFIYSCAGCCVATYVLGICDRHNDNIMLKTTGHMFHIDFGRFLGHAQ 1222
Query: 1313 MFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDL 1372
MFGN KR DRAPFV T DM YVINGG++P+ RF FV+LCC A+N++R H L+L
Sbjct: 1223 MFGNIKR----DRAPFVFTSDMAYVINGGDKPSSRFHDFVDLCCQAYNLIRKHTHLFLNL 1278
Query: 1373 FALP-SC---------------DSGGSERTVAGGRPQMSLSGVPGVTSAAVSYVRXXXXX 1416
L SC D+ + T A + + S A
Sbjct: 1279 LGLMLSCGIPELSDLEDLKYVYDALRPQDTEANATTYFTRLIESSLGSVATKLNFFIHNL 1338
Query: 1417 XXXXXXXXXXXXRLIHSSLKSNMTQEGRLVSVECLGYEKRYDPEKHYVYALRIYRLGQAT 1476
L +S + GR+ V +EK + P K Y+Y +++ R
Sbjct: 1339 AQMKFTGSDDRLTLSFASRTHTLKSSGRISDVFLCRHEKIFHPNKGYIYVVKVMRENTHE 1398
Query: 1477 PSVLYRSYKHFTELYQKICLHFP 1499
+ + R+++ F EL+ K+ L FP
Sbjct: 1399 ATYIQRTFEEFQELHNKLRLLFP 1421
>UniRef50_A7RRA6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1310
Score = 434 bits (1069), Expect = e-120
Identities = 275/703 (39%), Positives = 361/703 (51%), Gaps = 75/703 (10%)
Query: 681 IEAVHCLPLCWSHDEYMFHAQ--IYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLE 738
I + H +PL W D F +Y+G L + T SK+ F + + WL
Sbjct: 319 ISSAHRIPLYWKQDFENFSVDGGVYYGGCLLCPIETTTQSKLT-RKFSELLQWGDWLKF- 376
Query: 739 DLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQ 798
D+PV LPRESRL LTL+G P+ PS++ A LGW ALQ
Sbjct: 377 DIPVKRLPRESRLCLTLYGTK--------PSSKGNPSARSA------------LGWVALQ 416
Query: 799 LFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXXVVNIEIPLYAHTGVKWTSG 858
LF+F+G+L +G +L LWP S +V E L
Sbjct: 417 LFNFNGVLLTGTQILGLWPDSKANPVGSCTSNLLHPNSVLLLVTFERYL----------- 465
Query: 859 EEDKQKNISLKDLPSFDSLDGHTQSQLLHLIEQ----GAYQRMPTECREVMWEKRQYLVQ 914
E + S D P FD +D L E+ + + R ++WE R Y
Sbjct: 466 SEIVFPDCS--DFPGFDDMDHCIPEADYGLFEEILMKDLFNELKPNERSILWEHRFYCRS 523
Query: 915 IPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLN 974
+P ALPLVL +A +W ++ LL W SP++AM LL FPD VR A + +
Sbjct: 524 VPRALPLVLSSAPSWEIQSLPEIYKLLHTWSPMSPVDAMELLKVNFPDRHVRSMAVRWMA 583
Query: 975 EMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQA 1034
SDD+LC LPQL QAL++E Y FW
Sbjct: 584 NFSDDELCDYLPQLVQALKYEIYHDSALTRFLVRRALGNVRLMHLLFWF----------- 632
Query: 1035 PHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLC 1094
L+D SE R+ ++L LL ICGE + Q LV L
Sbjct: 633 ---------LKDKISEP-------QFGQRFQVILGGLLNICGEAQKEEFTFQDDLVTELI 676
Query: 1095 EMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTL 1154
++A VK AK+ LP+ V +DV+SC YF+SN+
Sbjct: 677 KVARKVKSAKDSARNNILQQELAALAGKLCCV-FRLPITPSLEVVGMDVRSCGYFTSNSA 735
Query: 1155 PLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPT 1212
PL++ F D + +FK+GDD+RQD L +Q++ IM+ +WL+ GLDL+++T+Q + T
Sbjct: 736 PLRLVFRNVDPFGENVNVIFKMGDDMRQDTLTMQLVGIMNKIWLQEGLDLKIITYQCMAT 795
Query: 1213 SNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCA 1272
GMIEIV++++TLR I TE+GLTGSFKD+ I WL K NP E EY+RA +NFTASCA
Sbjct: 796 GPGMGMIEIVSDSQTLREIHTEFGLTGSFKDESINRWLLKFNPDEKEYRRAVENFTASCA 855
Query: 1273 GYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTH 1332
GY VATY+LGICDRHNDNIM+ SGHLFHIDF K LG AQMFGNFKR DRAPFVLT
Sbjct: 856 GYCVATYVLGICDRHNDNIMIHRSGHLFHIDFSKILGHAQMFGNFKR----DRAPFVLTP 911
Query: 1333 DMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
DM YVINGG RP+ RFQHF++LC AFN++R H + L+L +L
Sbjct: 912 DMAYVINGGYRPSPRFQHFIDLCSRAFNLIRRHSNLFLNLLSL 954
Score = 80.2 bits (189), Expect = 4e-13
Identities = 68/251 (27%), Positives = 116/251 (46%), Gaps = 18/251 (7%)
Query: 365 DSEHKAFLKMALDVRKKFVYTDERTNPGHVIAARSGGKYPPN-----TSIKILVHHAHSD 419
D+E AF +M +VR F + E +N G+V++ ++ T + +++
Sbjct: 15 DAEVIAFGEMLSEVRSNFHWY-ESSNRGYVLSPALPSRFGKTICNRETEVVVVIFTEGRR 73
Query: 420 EPITFTSDVESKVEHVI-LTVVCSLDEDIREDMSG--YMLRVRGAKEYLTPGSSLSEYDY 476
+ F D + V+ V+ LT+ C + D+ + + ++L++ G EYL L EY+Y
Sbjct: 74 DTFRFAIDTWASVKEVLELTLSCLSNSDVNIEHASTTHVLKICGRSEYLEAQRKLVEYEY 133
Query: 477 IRECVRLEKDVTLCLHEGRDST--LARTERDDAKD-SHLTLDDLFPAQGATPMLSFDNLS 533
I+EC++ +K+V L E + LART DD D + D F T + + L+
Sbjct: 134 IQECLKFQKEVQFVLLENEKVSRHLARTASDDEIDLVPRSYKDFFNLSHTTAVSQY-GLT 192
Query: 534 ILLETLEGELSRAI--GVTSAEGSCSPKAVFQAVKAICALAGGVET--LHV-THTLNAFA 588
+L+E+ E SR + + P + Q KAIC+ +ET +HV LN F
Sbjct: 193 VLVESFTEETSRLLQEATSLVNPKFEPSPIIQLTKAICSTLASIETADIHVAVDALNLFH 252
Query: 589 QACTAQGANNV 599
+ NV
Sbjct: 253 EVNKNSAVLNV 263
>UniRef50_Q4T9W9 Cluster: Chromosome undetermined SCAF7485, whole
genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome undetermined SCAF7485, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1841
Score = 331 bits (814), Expect = 7e-89
Identities = 189/421 (44%), Positives = 240/421 (57%), Gaps = 38/421 (9%)
Query: 1055 DASMSASW--RYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXX 1112
DA +W RY +L ALL +CG L +Q LV L +A V+ A
Sbjct: 1049 DAVQDPAWGGRYERVLGALLCLCGAKLRAEFYKQTQLVALLARVAERVRQAGGSVRQAAL 1108
Query: 1113 XXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTD--NAVIPA 1170
LPL+ +L++K+C++F+SN +PLK+ + D I
Sbjct: 1109 MDGLESVQNFFQRDSCRLPLSPSLVAKELNLKACSFFNSNAVPLKLALVNADPLGEEINV 1168
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSN---------------- 1214
MFKVG+DLRQD L LQ+I++MD +WL+ GLDLRMV F+ + T
Sbjct: 1169 MFKVGEDLRQDMLALQMIRVMDRIWLQEGLDLRMVNFKCISTGKHRGDGARTRTHTTHTH 1228
Query: 1215 ----------SKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRAR 1264
S GM+E+V ++TLR IQ E+G+TGSFKDKP+AEWL K+NP+E EY +A
Sbjct: 1229 THTPSRPGPVSAGMVELVPSSDTLRKIQVEYGVTGSFKDKPLAEWLRKYNPAEDEYDKAS 1288
Query: 1265 DNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYID 1324
+NF SCAG VATY+LGICDRHNDNIML++SGH+FHIDFGKFLG AQMFG+FKR D
Sbjct: 1289 ENFIYSCAGCCVATYVLGICDRHNDNIMLRSSGHMFHIDFGKFLGHAQMFGSFKR----D 1344
Query: 1325 RAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGSE 1384
RAPFVLT DM YVINGGERPT RFQ FV+LCC A+N++R H L L AL
Sbjct: 1345 RAPFVLTSDMAYVINGGERPTSRFQLFVDLCCQAYNLMRKHSGLFLSLLALVRSARSSPR 1404
Query: 1385 R---TVAGGRPQMSLSGVPGVT-SAAVSYVRXXXXXXXXXXXXXXXXXRLIHSSLKSNMT 1440
R T QM+ SG+P ++ S + YV RLI SSL S T
Sbjct: 1405 RRLLTTLHLALQMTSSGLPELSGSQDLKYVFDALQPHSTDADATVFFTRLIESSLGSVAT 1464
Query: 1441 Q 1441
+
Sbjct: 1465 K 1465
Score = 81.8 bits (193), Expect = 1e-13
Identities = 62/221 (28%), Positives = 105/221 (47%), Gaps = 11/221 (4%)
Query: 378 VRKKFVYTDERTNPGHV----IAARSGGKYPPNTSIKILVHHAHSDEPITFTSDVESKVE 433
+R +F ++ TNPG+V I R G + S+K+ + + S +P+TFT DV S VE
Sbjct: 391 LRSRFPHSQLSTNPGYVLSPVITQRDAGG-DASCSVKVSIEISESQQPVTFTCDVSSPVE 449
Query: 434 HVILTVVCSLDEDIRE-DMSGYMLRVRGAKEYLTPGSSLSEYDYIRECVRLEKDVTLCLH 492
+I +C + +D+ + D S Y+L+V G +E L SL ++Y++ C + E +++L L
Sbjct: 450 LLISQTLCWVHDDLDQVDFSSYLLKVCGREEVLQNKRSLGSHEYVQNCRKWENEISLQLL 509
Query: 493 EGRDSTLARTERDDAKDSHLTLD-DLFPAQGATPMLSFDNLSILLETLEGELSRAIGVTS 551
S++ R A+D H +D + Q P L + L+G +
Sbjct: 510 S--QSSMRRDLARTAEDDHAPVDLEKHLEQVDRPFRENVTRQGLADYLDGYHKQVNICLQ 567
Query: 552 AEGS--CSPKAVFQAVKAICALAGGVETLHVTHTLNAFAQA 590
E S + + V Q +K +C VET +T + A
Sbjct: 568 NENSQYKTVERVVQTLKNLCCALDEVETQSITEAVKRLRHA 608
Score = 67.3 bits (157), Expect = 3e-09
Identities = 26/65 (40%), Positives = 43/65 (66%)
Query: 1439 MTQEGRLVSVECLGYEKRYDPEKHYVYALRIYRLGQATPSVLYRSYKHFTELYQKICLHF 1498
+ Q+GRL+ ++KRY+P+KHY Y +R+ R G A P ++R++ F EL+ K+ + F
Sbjct: 1498 LKQDGRLLHAAIFSFQKRYNPDKHYTYVVRLQREGHAEPQFIFRTFDDFLELHNKLSILF 1557
Query: 1499 PLAKV 1503
PL K+
Sbjct: 1558 PLWKL 1562
Score = 44.0 bits (99), Expect = 0.032
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 27/153 (17%)
Query: 679 FCIEAVHCLPLCWSHDEYMFHA-QIYHGTRPL----KTL-RFTQASKIECGGFYPRIIFD 732
F + AVH +P W Y+F + + Y+ T L K L + Q+ K+ G Y +
Sbjct: 713 FTVYAVHGIPASWVSSFYLFGSYEKYYLTCSLTHNGKNLFKPIQSKKV---GTYKNFFYH 769
Query: 733 T-WLNLEDLPVNT--LPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQ 789
W L PV LP E+ L LTL G + N P S + + +
Sbjct: 770 IKWDELISFPVAVAILPLEALLTLTLFGVLNQ-------NAGGSPDSNKQRKAPE----- 817
Query: 790 VELGWAALQLFDFDGMLSSGNYVLPLWPTSCDR 822
+LG A+ LFDF G+L+ G+ ++ LW SCD+
Sbjct: 818 -QLGKASTPLFDFRGLLAKGSRLMCLW--SCDQ 847
>UniRef50_UPI0000ECD2E3 Cluster: Phosphatidylinositol-4-phosphate
3-kinase C2 domain-containing gamma polypeptide (EC
2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma)
(PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).; n=2; Gallus
gallus|Rep: Phosphatidylinositol-4-phosphate 3-kinase C2
domain-containing gamma polypeptide (EC 2.7.1.154)
(Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2
gamma) (PI3K-C2gamma). - Gallus gallus
Length = 1220
Score = 312 bits (766), Expect = 5e-83
Identities = 179/477 (37%), Positives = 257/477 (53%), Gaps = 34/477 (7%)
Query: 902 REVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFP 961
+ ++W R Y +LPLVL +A +W ++ ++R W +P+ A+ LL FP
Sbjct: 448 KRILWFYRYYCNNQNCSLPLVLGSAPSWDRTTVSEMYSVMRKWRFSNPVEALGLLAFSFP 507
Query: 962 DVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXF 1021
D +R TA + + +S+D+L LPQL Q L+ E
Sbjct: 508 DKDIRRTAVQQIENLSNDELLEYLPQLVQVLKFEWSLEGPLVKL---------------- 551
Query: 1022 WLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNK 1081
LL SL +I Q HQ + + +NA+ + W Y +L AL G+ LN
Sbjct: 552 -LLNRSLQSI-QVAHQLYWLL-------KNAQNEVHFKV-W-YRKLLAALQFTAGKALNN 600
Query: 1082 TLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTA-LPLALHKYVHD 1140
+++ L++ L + A VK A + LPL V
Sbjct: 601 EFSKEEKLIRILEDTAEKVKVASDAKRKEVLKMELNRLQQFFQEVKVCRLPLNPALVVQG 660
Query: 1141 LDVKSCTYFSSNTLPLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKA 1198
++ SC+YF+SN PLKI FI + + I +FK+GDDLRQD LVLQ++++MD +WL+
Sbjct: 661 IEADSCSYFTSNAFPLKIRFINANAPSGNINIIFKIGDDLRQDMLVLQIVRVMDNIWLQE 720
Query: 1199 GLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSEL 1258
GLD++M+ ++ L T +G++++V +A TL I E GL G K+ I +W H+ E
Sbjct: 721 GLDMQMIIYRCLSTGKGQGLVQMVPDATTLAKIHRESGLIGPLKENTIRKWFRHHHRLES 780
Query: 1259 EYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFK 1318
YQ A NF SCAG+ V T++LG+CDRHNDNIML SGH+FHIDFG+FLG AQ FG+ +
Sbjct: 781 SYQEAIRNFFHSCAGWCVVTFILGVCDRHNDNIMLTNSGHMFHIDFGRFLGHAQTFGSIR 840
Query: 1319 RLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
R DRAPF+ T +M Y I G + QRFQ FVELCC A+NIVR H +L+L +
Sbjct: 841 R----DRAPFIFTSEMEYFITEGGKSPQRFQEFVELCCRAYNIVRKHSQLLLNLLEM 893
Score = 43.2 bits (97), Expect = 0.056
Identities = 52/233 (22%), Positives = 96/233 (41%), Gaps = 17/233 (7%)
Query: 355 SIVKIRTRNYDSEHK-AFLKMALDVRKKFVYTDERTNPGHV--IAARSGGKYPPNTSIKI 411
SI I+ +E+ +F +R + D +TN G + +A + ++I
Sbjct: 3 SIQLIKANQGSNENAVSFCNTVEKIRNTYPACDLKTNTGKIWSVATKFPDHILGKIRLRI 62
Query: 412 LVHHAHSDEPITFTSDVESKVEHVILTVV-CSLDEDIREDMSGYMLRVRGAKEYLTPGSS 470
+ S P+ T +I+ ++ C+ + E+ +L V G+ E+L S
Sbjct: 63 SIWTDSSPSPLLLTQHAGCITHDLIVEILRCTNQYPVHEEC---LLSVCGSDEFLQNNHS 119
Query: 471 LSEYDYIRECVRLEKDVTLCLHEGRD--STLARTERDDAKDSHLTLDDLFPAQGATPMLS 528
L ++ +R+ D+ L LH + +LAR DD ++++L A L+
Sbjct: 120 LGNHESLRKATT---DIHLHLHSTTNLKQSLARVHEDD--QGRFSVNELLEYTCAW-RLT 173
Query: 529 FDNLSILLETLEGELSRAIGVTSAEGSCSPKAVFQAVKAICALAGGVETLHVT 581
NL L G++ + + E V + KAIC++ VET +T
Sbjct: 174 RQNLFAALRKYRGQVEHLL--QNEENPYKVDYVIEVAKAICSVLCFVETRQIT 224
>UniRef50_O75747 Cluster: Phosphatidylinositol-4-phosphate 3-kinase C2
domain-containing gamma polypeptide; n=15; Eutheria|Rep:
Phosphatidylinositol-4-phosphate 3-kinase C2
domain-containing gamma polypeptide - Homo sapiens
(Human)
Length = 1448
Score = 308 bits (756), Expect = 8e-82
Identities = 179/479 (37%), Positives = 251/479 (52%), Gaps = 34/479 (7%)
Query: 900 ECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPC 959
E + +W R Y +LPLVL +A W ++ +LR W PL A+ LL
Sbjct: 672 EKKRYLWFYRFYCNNENCSLPLVLGSAPGWDERTVSEMHTILRRWTFSQPLEALGLLTSS 731
Query: 960 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 1019
FPD +R+ A + L+ + +D+L LPQL QA++ E
Sbjct: 732 FPDQEIRKVAVQQLDNLLNDELLEYLPQLVQAVKFEWNLESPLVQLLLHRSLQSIQVAHR 791
Query: 1020 XFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENL 1079
+WLL +NAE +A SW Y +L AL G+ L
Sbjct: 792 LYWLL-------------------------KNAENEAYFK-SW-YQKLLAALQFCAGKAL 824
Query: 1080 NKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTA-LPLALHKYV 1138
N ++Q L+K L ++ VK A + T LPL +
Sbjct: 825 NDEFSKEQKLIKILGDIGERVKSASDHQRQEVLKKEIGRLEEFFQDVNTCHLPLNPALCI 884
Query: 1139 HDLDVKSCTYFSSNTLPLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVIKIMDTLWL 1196
+D +C+YF+SN LPLKI FI + I +FK GDDLRQD LVLQ+I++MD +WL
Sbjct: 885 KGIDHDACSYFTSNALPLKITFINANLMGKNISIIFKAGDDLRQDMLVLQLIQVMDNIWL 944
Query: 1197 KAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPS 1256
+ GLD++M+ ++ L T + ++++V +A TL I GL G K+ I +W ++HN
Sbjct: 945 QEGLDMQMIIYRCLSTGKDQRLVQMVPDAVTLAKIHRHSGLIGPLKENTIKKWFSQHNHL 1004
Query: 1257 ELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGN 1316
+ +Y++A NF SCAG+ V T++LG+CDRHNDNIML SGH+FHIDFGKFLG AQ FG
Sbjct: 1005 KADYEKALRNFFYSCAGWCVVTFILGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGG 1064
Query: 1317 FKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
KR DRAPF+ T +M Y I G + Q FQ FVELCC A+NI+R H +L+L +
Sbjct: 1065 IKR----DRAPFIFTSEMEYFITEGGKNPQHFQDFVELCCRAYNIIRKHSQLLLNLLEM 1119
>UniRef50_Q4RSB1 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 13
SCAF15000, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 666
Score = 283 bits (693), Expect = 3e-74
Identities = 181/516 (35%), Positives = 265/516 (51%), Gaps = 34/516 (6%)
Query: 863 QKNISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLV 922
Q+ I+L L +F + ++L + ++ + + +W KR + L L+
Sbjct: 123 QRPIALPGLITFTEPCEELRRKMLAVSKKHCLCFLTQNEKSFLWTKRHCSDKGSTFLHLL 182
Query: 923 LLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLC 982
L A W + ++ ++ W P A+ LL FPD VR A ++ D DL
Sbjct: 183 LGGAPRWQPEDLTEIYTIVENWPIHLPEEALFLLSNNFPDPTVRSAAVHFFKQIPDGDLE 242
Query: 983 RVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQAPHQEFLGI 1042
LPQL QAL+ E LL S+ N+ A +L
Sbjct: 243 VFLPQLVQALKSEW-----------------ELDGPLVMLLLERSVRNVQVAQQLYWL-- 283
Query: 1043 NLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKC 1102
LED A+TD SW + AL CG+ L K L + L +L + A ++
Sbjct: 284 -LED-----AQTDPHYH-SWLRKIQA-ALQHCCGQALRKELQLETRLTSALIQAAEKIRT 335
Query: 1103 AKEXXXXXXXXXXXXXXXXXXXXQPTA-LPLALHKYVHDLDVKSCTYFSSNTLPLKINFI 1161
A++ + LPL V LD ++C ++SN PL I+FI
Sbjct: 336 AEKTRRKNILKREASQIEDFFKDGVSCCLPLDPAVRVKGLDAEACKVYNSNAAPLGISFI 395
Query: 1162 GTDNAV--IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMI 1219
TD + + K GDDL+QD L+LQ++++MD +WL+ GLDL+M+T++ L T ++G++
Sbjct: 396 CTDPLAKNVSVICKTGDDLQQDMLILQIVRMMDRVWLQEGLDLQMITYRCLSTGKTQGLV 455
Query: 1220 EIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATY 1279
E+V +A TL IQ EWGL GS ++ + +W N ++ +Y +A NF SCAG+ VAT+
Sbjct: 456 EVVPDAVTLGKIQQEWGLAGSLREDTLEKWFHMWNKTKEDYDKAVMNFIHSCAGWCVATF 515
Query: 1280 LLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVIN 1339
+LGICDRHNDNIMLK SGH+FHIDFGK +G+AQ FG+FKR DR+PF+ T +M + +
Sbjct: 516 ILGICDRHNDNIMLKHSGHMFHIDFGKIMGNAQKFGSFKR----DRSPFIFTSEMQHSHH 571
Query: 1340 GGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+ QR FVELCC A+NIVR IL L L
Sbjct: 572 RWGQKPQRLHRFVELCCEAYNIVRQRSALILGLLEL 607
>UniRef50_P54673 Cluster: Phosphatidylinositol 3-kinase 1; n=2;
Dictyostelium discoideum|Rep: Phosphatidylinositol
3-kinase 1 - Dictyostelium discoideum (Slime mold)
Length = 1570
Score = 256 bits (628), Expect = 3e-66
Identities = 194/651 (29%), Positives = 297/651 (45%), Gaps = 67/651 (10%)
Query: 734 WLNLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELG 793
WL ++ + LP ++RL ++++ + T+D +E ++ + + +G
Sbjct: 918 WLVFTNIDYSNLPVDARLSISVYSANE-TVDDV----------EEIKNLDEATKKLTPIG 966
Query: 794 WAALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXXVVNIE---IPLYAH 850
W + + DF L G L LWP+ + E +P+
Sbjct: 967 WINVMITDFKYQLRQGMVELSLWPSDFSNPLGTCSNNPSSSQSVGLTLEFEEFNLPVLFP 1026
Query: 851 TGVKWTSGE---EDKQKNISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWE 907
K+++ E NI+ ++ F + T L ++Q Y ++ W
Sbjct: 1027 RKTKFSTSVSVIEQPPTNINSNEMREF--FEQITALDPLSDLKQEKYNQL--------WT 1076
Query: 908 KRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRE 967
R Y + P LP ++L+ ++ I LL W K P ++ LL + VRE
Sbjct: 1077 LRHYSILFPQVLPRLMLSVPWTQATAVDEAISLLDRWPKLKPYESLELLDAKHANRKVRE 1136
Query: 968 TAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHS 1027
A L ++S+D+L +L QL Q L++E + FW L
Sbjct: 1137 FAVTCLEDLSEDELLDILLQLVQVLKYEPFHDSKLSRFLLRKAILNRNIGHSFFWYLKSD 1196
Query: 1028 LPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQ 1087
L H + N SE R+ ++L + L CG + + LL+Q
Sbjct: 1197 L-------H--------DSNLSE------------RFGILLESYLYACGAHRIE-LLKQM 1228
Query: 1088 LLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCT 1147
++ +L E+A +K K+ T P + L +
Sbjct: 1229 EVINNLTEVAKKIKPLKDQDRREFMIKEFESLEWPKRFHLTLNP---RFESNGLIINKSK 1285
Query: 1148 YFSSNTLPLKINFIGTD-NA-VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMV 1205
Y S LPL+++F TD NA I +FK GDDLRQD L LQ+I++MD LW K GLDL++
Sbjct: 1286 YMDSKKLPLRLSFTNTDMNADPIEVIFKAGDDLRQDMLTLQMIRLMDKLWQKEGLDLKLS 1345
Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAIQ-TEWGLTGSFKDKPIAEWLAKHNPSELEYQRAR 1264
+ + T + GMIE+V +ET IQ +E G F+ + + +HN S++EYQ+A
Sbjct: 1346 PYGCISTGDMIGMIEVVLNSETTAKIQKSEGGGAFRFQVGSFGQLILQHNKSDMEYQKAV 1405
Query: 1265 DNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYID 1324
D F SCAGY VATY+LGI DRHNDN+M+ G LFHIDFG FLG+ + FKR +
Sbjct: 1406 DTFILSCAGYCVATYVLGIGDRHNDNLMVTKGGRLFHIDFGHFLGNYKKKFGFKR----E 1461
Query: 1325 RAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
RAPFV T D YV+ G E + +F FV CC +NIVR + ++LFA+
Sbjct: 1462 RAPFVFTPDFCYVMGGKE--SFKFSQFVNYCCTGYNIVRKNAKLFMNLFAM 1510
>UniRef50_UPI0000498E9A Cluster: phosphatidylinositol 3-kinase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: phosphatidylinositol
3-kinase - Entamoeba histolytica HM-1:IMSS
Length = 1115
Score = 246 bits (602), Expect = 4e-63
Identities = 184/599 (30%), Positives = 265/599 (44%), Gaps = 54/599 (9%)
Query: 788 EQVELGWAALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXXVVNIEIPL 847
++V +G+ LFDF L SG L LWP D +++I+ P
Sbjct: 507 KKVVIGFVNTPLFDFQNFLLSGYVNLRLWP---DEESDAVSSPLQNPSPTAPIISIKFP- 562
Query: 848 YAHTGVK-WTSGEEDKQKNISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMW 906
+K + E K + L + Q LH +Q + E + +W
Sbjct: 563 --DPVIKIFYQPYEAKYPQVPKNLL----KISNDVQQLALH---NDPFQPLTNEQKNEIW 613
Query: 907 EKR-QYLVQIPGALPLVLLAATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVA 964
+ R L+Q P ++ L LL A W RE++ L+++W SP+ + LL
Sbjct: 614 QNRFNILIQFPDSIDL-LLRAVPWTDYKAREEMADLIKIWPGISPIQVIGLLDVRNSFTP 672
Query: 965 VRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXF-WL 1023
R+ A +LL E D + LPQ Q L+ E+Y F WL
Sbjct: 673 ARDYAVRLLEETKDQVILGYLPQFIQVLKFESYTCSSLALFLLKRALKNRGDMGQLFYWL 732
Query: 1024 LVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTL 1083
LV EN +T S+ R ++L +CG L K L
Sbjct: 733 LV-----------------------GENEKTKISL----RSKILLEVYNSMCGTQL-KEL 764
Query: 1084 LRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDV 1143
Q+ +K + E AV+ K K+ LP + V + V
Sbjct: 765 KTQENFIKIIEETAVNAKHWKDDEIKTNLPNMLTVVNNALQGSRLTLPFTSRETVSCVVV 824
Query: 1144 KSCTYFSSNTLPLKINFIGT---DNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGL 1200
C F SN P+ + F + +FKVGD+L QD L LQ+ K+MD LW K G+
Sbjct: 825 NKCKVFDSNAHPILLCFQSSPIFSQQETRFIFKVGDNLMQDMLTLQMFKLMDDLWKKNGI 884
Query: 1201 DLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEW-GLTGSFKDKPIAEWLAKHNPSELE 1259
D RM + L TS + G+I+ V ET+ +IQT+ G+TG F D I EW+ N E +
Sbjct: 885 DFRMTIYNVLATSTTSGIIQFVPNCETVNSIQTKGRGITGVFDDACIYEWIKSKNLEEKD 944
Query: 1260 YQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR 1319
+ A +NFT SCAGY VATY++G+ DRHNDNIM+ GHLFHIDFG FLG+ G + +
Sbjct: 945 LKNAIENFTYSCAGYCVATYVIGVGDRHNDNIMVSKDGHLFHIDFGHFLGNIIKLGFYNK 1004
Query: 1320 LVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSC 1378
+ APFVLT+D ++VI G T + F +C F I+R + + F + C
Sbjct: 1005 ----ESAPFVLTNDFMFVITMGNTDTDNYSFFENICTKGFMILRNNAKTFIYSFMMMLC 1059
>UniRef50_P54674 Cluster: Phosphatidylinositol 3-kinase 2; n=2;
Dictyostelium discoideum|Rep: Phosphatidylinositol
3-kinase 2 - Dictyostelium discoideum (Slime mold)
Length = 1858
Score = 239 bits (584), Expect = 6e-61
Identities = 170/531 (32%), Positives = 256/531 (48%), Gaps = 41/531 (7%)
Query: 877 LDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYG-DHRE 935
LD +L L++ ++ E +++++ R P AL LL+ NW D
Sbjct: 1333 LDLDEARRLKALMDSDPLVQLSAEDKKLVYGYRHIYKSKPKALAKFLLSV-NWIDPDQVT 1391
Query: 936 QLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
+ W P+ A+ +L F D VR A K++N SD + L QLTQ L++E
Sbjct: 1392 DAYRQMNDWALLKPVQALEILDAKFADEHVRNFAIKIINSFSDAEFSDFLLQLTQVLKYE 1451
Query: 996 TYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETD 1055
Y L+ +L N + H F + E + E E
Sbjct: 1452 PYHNSDLTHI-----------------LIQRALSNRSRIGHFFFWFLKSEMHTPEIEE-- 1492
Query: 1056 ASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXX 1115
RY L+L L CG + + L++Q ++KSL +A++VK +
Sbjct: 1493 -------RYGLLLEGYLRSCGTH-RQDLIKQNQVLKSLHTVAMAVK--QTNGSSERKKVL 1542
Query: 1116 XXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIP--AMFK 1173
LPL L + C Y S LPL + F + P +FK
Sbjct: 1543 MEGLSKIKFPDTFQLPLDPRWEAKGLIIDKCRYMDSKKLPLWLVFENVEPHAKPLTVIFK 1602
Query: 1174 VGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQT 1233
VGDDLRQD L LQV++IMD W +G+DLR+ ++ + T + GM+E+V A T+ I
Sbjct: 1603 VGDDLRQDILTLQVLRIMDKFWKNSGMDLRLQPYKCIATGDGIGMLEVVLNANTIANINK 1662
Query: 1234 EWGLTGSF-KDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIM 1292
+ G TG+ ++K + WL + N +E EY +A + F SCAGY VATY++GI DRH+DNIM
Sbjct: 1663 DAGGTGALLEEKTLVNWLKECNKTEAEYNKAVETFILSCAGYVVATYVMGIGDRHSDNIM 1722
Query: 1293 LKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFV 1352
+ GHLFHIDFG FLG+ + FKR +RAPF+ T + ++ G + ++ F+ FV
Sbjct: 1723 ITKLGHLFHIDFGHFLGNYKKKYGFKR----ERAPFIFTPQYMAIVGG--KDSENFKRFV 1776
Query: 1353 ELCCMAFNIVRAHHDHILDLFALPSCDSGGSERTVAGGRPQMSLSGVPGVT 1403
CC A+NI+R + D ++LF L +G E VA + + PG++
Sbjct: 1777 TTCCSAYNILRKNTDLFINLFQL-MLSTGIPELQVAEDIDYLRKALAPGLS 1826
>UniRef50_P42338 Cluster: Phosphatidylinositol-4,5-bisphosphate
3-kinase catalytic subunit beta isoform; n=60;
Euteleostomi|Rep: Phosphatidylinositol-4,5-bisphosphate
3-kinase catalytic subunit beta isoform - Homo sapiens
(Human)
Length = 1070
Score = 234 bits (573), Expect = 1e-59
Identities = 190/653 (29%), Positives = 299/653 (45%), Gaps = 50/653 (7%)
Query: 739 DLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQ 798
D+ + LPR +RL ++ + + +P Q +G V Y + W
Sbjct: 388 DINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYP---VAWVNTM 444
Query: 799 LFDFDGMLSSGNYVLPLWPTSCDRRXXXX----XXXXXXXXXXXXVVNIEIPLYAHTGVK 854
+FDF G L +G+ +L W + D ++++ P
Sbjct: 445 VFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHVKFPENKKQPYY 504
Query: 855 WTSGEE--DKQKNISLKDLPSFDSLDGHTQSQLL-HLIEQGAYQRMPTECREVMWEKRQY 911
+ ++ +K I+ D + S G +L ++++ ++ +++W RQ
Sbjct: 505 YPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQD 564
Query: 912 LVQI-PGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAA 970
+I P +LP +LL+ + QL LL++W K P A+ LL +PD VRE A
Sbjct: 565 CREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAV 624
Query: 971 KLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPN 1030
L +MSD++L + L QL Q L++E + FW L S +
Sbjct: 625 GCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHL-RSEVH 683
Query: 1031 IPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLV 1090
IP Q G+ LE A S + +L + E LNK L+
Sbjct: 684 IPAVSVQ--FGVILE----------AYCRGSVGHMKVLSKQV----EALNKLKTLNSLIK 727
Query: 1091 KSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFS 1150
+ AV + AK Q P + + +L V+ C Y
Sbjct: 728 LN----AVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVI---LSELYVEKCKYMD 780
Query: 1151 SNTLPLKINF----IGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVT 1206
S PL + + G D+ + +FK GDDLRQD L LQ++++MD LW +AGLDLRM+
Sbjct: 781 SKMKPLWLVYNNKVFGEDS--VGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLP 838
Query: 1207 FQALPTSNSKGMIEIVTEAETLRAIQ---TEWGLTGSFKDKPIAEWLAKHNPSELEYQRA 1263
+ L T + G+IE+V+ +ET+ IQ + +F + WL ++N + + RA
Sbjct: 839 YGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGD-DLDRA 897
Query: 1264 RDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYI 1323
+ FT SCAGY VA+Y+LGI DRH+DNIM+K +G LFHIDFG LG+ + KR
Sbjct: 898 IEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKR---- 953
Query: 1324 DRAPFVLTHDMVYVINGGER-PTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+R PF+LT+D ++VI G+ T++F F + C A+ I+R H + + LFAL
Sbjct: 954 ERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFAL 1006
>UniRef50_Q20187 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 1607
Score = 233 bits (569), Expect = 4e-59
Identities = 137/381 (35%), Positives = 193/381 (50%), Gaps = 26/381 (6%)
Query: 1143 VKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDL 1202
++ C+ F+SN PLKI F G N + K DD+RQDA V++++ MD +W GLDL
Sbjct: 1030 IEECSVFNSNAKPLKIVFRGL-NMNYSIIHKRDDDMRQDAFVMKMLNEMDRIWKSNGLDL 1088
Query: 1203 RMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQR 1262
RM+TF+ +P +GM E+V TL IQ E GL G D+ + +WL KHN E Y+
Sbjct: 1089 RMITFRIMPVGYRRGMGELVLNCATLMEIQKEEGLRGVLNDEILRKWLMKHNSDEFAYKE 1148
Query: 1263 ARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVY 1322
A++NF SCAG+ + TY+LGI DRHNDNI+ +GH+FHIDFGK++GD QM F+R
Sbjct: 1149 AQENFIRSCAGWCIVTYVLGIGDRHNDNILFTKNGHVFHIDFGKYMGDWQMAAGFRR--- 1205
Query: 1323 IDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSC-DSG 1381
DR PFV T +M +VIN G PTQ Q F++ CC AFN +R + + + +L + +C D
Sbjct: 1206 -DRVPFVFTTEMFHVINNGRAPTQYNQKFIDYCCKAFNHLRRNKNTLTNLLRIMACSDIP 1264
Query: 1382 G---SERTVAGGRPQMSLSGVPGVTSAAVSYVRXXXXXXXXXXXXXXXXXRLIHSSLKSN 1438
G + LS + I S +
Sbjct: 1265 GINMDSLAFVENNLMLDLSDTDATVQFTAMIQNSLGSAFVRLNFVAHTVAQFISSRPSFS 1324
Query: 1439 MTQEGRLVSVECLGYEKRYDP----------EKH----YVYALRI--YRLGQATPSVLYR 1482
+L V L Y + D EKH +Y ++ +R A S +YR
Sbjct: 1325 KQDPNKLSFVPEL-YTENSDGRISRVTVLKFEKHCIPNKIYMYKVEVHRKNVAVSSFIYR 1383
Query: 1483 SYKHFTELYQKICLHFPLAKV 1503
S+ F EL+ K+ FP+ V
Sbjct: 1384 SFAEFEELHTKLRARFPMMAV 1404
Score = 107 bits (256), Expect = 3e-21
Identities = 88/320 (27%), Positives = 145/320 (45%), Gaps = 26/320 (8%)
Query: 681 IEAVHCLPLCWS--HDEYMFHAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLE 738
+ +VH +P W + E+ +YHGT+ L I+ F+PRI D + +
Sbjct: 606 LNSVHSIPEHWQSQYSEFYMSLDLYHGTQVLDGFSNKVPKTIKNDHFFPRIPLDLYAKFK 665
Query: 739 DLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQ 798
L + PRE+R+V+++ G + + +Q NE +P D+ V LG+ ++
Sbjct: 666 RLNLCQYPRETRIVVSISGTVRNS--AQAANEYNP----------DI----VMLGYCSVP 709
Query: 799 LFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXXVVNIEIPLYAHTGVKWTSG 858
L+D + + G LPL T ++ + + P+ + W +
Sbjct: 710 LYDENLFMRQGPLFLPL--TLLKKQPMLKPFGPYPY-----IKDARDPILIMSFKIWDTE 762
Query: 859 EEDKQKNISLKDLPS-FDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPG 917
I ++ +P F +LD TQ LL LIE + T+ ++++W+KR +L P
Sbjct: 763 IYFPNVVIDMQCIPQDFATLDIETQEYLLELIENQDTSTLETDDQDLIWQKRLHLTNQPE 822
Query: 918 ALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMS 977
ALPLVL + +W ++ +L W P AM LLP +PD +R A + L S
Sbjct: 823 ALPLVLSSLQDWSFGFVMRVYQILEEWAPLRPEIAMEFLLPKYPDERIRAHAVQSLARGS 882
Query: 978 DDDLCRVLPQLTQALRHETY 997
D L +PQ +ALR E Y
Sbjct: 883 TDFLYHTIPQFIEALRFELY 902
>UniRef50_P54675 Cluster: Phosphatidylinositol 3-kinase 3; n=5;
Eukaryota|Rep: Phosphatidylinositol 3-kinase 3 -
Dictyostelium discoideum (Slime mold)
Length = 1585
Score = 223 bits (546), Expect = 2e-56
Identities = 115/254 (45%), Positives = 154/254 (60%), Gaps = 11/254 (4%)
Query: 1127 PTALPLALHKYVHDLDV--KSCTYFSSNTLPLKINFIGTDNAVIPAMF--KVGDDLRQDA 1182
PT L + + L++ + C S +PL + F D P K GDDLRQD
Sbjct: 1175 PTELFVPFDPSIRILNIIPEKCKSMDSAKVPLWVTFKNADPFAPPLQMIAKTGDDLRQDI 1234
Query: 1183 LVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQT-EWGLTGSF 1241
L LQ++++MD +W LDL M ++ + T G+IE+V +ET IQ G++G+F
Sbjct: 1235 LTLQLLRLMDHMWKSQDLDLHMTIYRCIATGMGTGLIEVVPNSETAARIQAGAGGVSGAF 1294
Query: 1242 KDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFH 1301
K PIA WL HN +E YQ+A FT SCAGY VATY+LGI DRHNDNIM+ GHLFH
Sbjct: 1295 KQTPIANWLKNHNQTENSYQKAVSKFTLSCAGYCVATYVLGIGDRHNDNIMVDIHGHLFH 1354
Query: 1302 IDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNI 1361
IDFG FLG+ + F F+R ++APFVLT D VYVI G + P F FV++CC AFNI
Sbjct: 1355 IDFGHFLGNFKTFAGFQR----EKAPFVLTPDFVYVIGGKDSP--NFAFFVDICCKAFNI 1408
Query: 1362 VRAHHDHILDLFAL 1375
+R++ +++F L
Sbjct: 1409 IRSNAHVFINMFEL 1422
Score = 58.8 bits (136), Expect = 1e-06
Identities = 74/289 (25%), Positives = 125/289 (43%), Gaps = 42/289 (14%)
Query: 715 TQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPP 774
TQ+SK+ F ++++ W+N+ L V+ +P +R+ L L+ R +
Sbjct: 823 TQSSKLV--SFQDTVVWNEWVNIP-LAVSNIPNGARMCLGLNARYR-------------- 865
Query: 775 SSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSS-GNYVLPLWPTSCDRRXXXXXXXXXX 833
GD+ +GW +LFD G+L++ + L LWP +
Sbjct: 866 --------GDIF----NIGWVGHRLFDSKGILNTFAPFSLLLWPGKINP--IGTCVDNLE 911
Query: 834 XXXXXXVVNIEIPLYAHTGVKWTSGEEDKQKNISLKDLPSFDSLDGHTQSQL---LHLIE 890
++ E Y V T ED + KD + + L T ++ +I
Sbjct: 912 SKDQAIIIAFEFKDYV---VPKTIHYEDDLIELISKD-ENGNELPVVTMEEMDRVEQIIL 967
Query: 891 QGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHRE-QLIGLLRLWEKPSP 949
Q + E R ++W+ R + P AL LL + W + + LL++W S
Sbjct: 968 QDPLYSLNKEERLLIWKSRYFCHTKPQALSK-LLQSVEWTNYKQVGEAFQLLKIWPTLSA 1026
Query: 950 LNAMHLLLPCFPD-VAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
++A+ LL P F D V +RE K L++MSD +L L QL QA++H+ +
Sbjct: 1027 VDALELLDPKFADCVEIREYTVKCLDQMSDYELEIYLLQLVQAIKHDVF 1075
>UniRef50_Q4CUM7 Cluster: Phosphatidylinositol 3-kinase 2, putative;
n=3; Trypanosomatidae|Rep: Phosphatidylinositol 3-kinase
2, putative - Trypanosoma cruzi
Length = 1055
Score = 221 bits (540), Expect = 1e-55
Identities = 182/594 (30%), Positives = 263/594 (44%), Gaps = 48/594 (8%)
Query: 792 LGWAALQLFDFDGMLSSGNYVLPLWPTSCDRRXXX---XXXXXXXXXXXXXVVNIEIPLY 848
LG+A++Q+FD+ + +G + LW T + P+
Sbjct: 441 LGYASVQVFDYMACMQTGKIDMRLWSTKKKANPMCPIPKNSNKNDMGFSLIFPSFNKPVV 500
Query: 849 AHTGVKWTSGEEDKQKNISLKDLPSFDSLDGHTQSQLLHL---IEQGAYQRMPTECREVM 905
S D ++ + DL +L QL L + + T + ++
Sbjct: 501 IPNVAPPDSKRRDWEQQLLDSDLCLVGNLRESKIEQLRQLKRILASDPLTELTTIDKVLL 560
Query: 906 WEKRQYLVQIPGALPLVLLAATNWYGDHRE-QLIGLLRLWEKPSPLNAMHLLLPCFPDVA 964
W+ R L+ P AL LLA NW + + +L W P++A+ LL + D+
Sbjct: 561 WKHRGELILRPRALAKFLLAV-NWLRPYAVYEAHTILPQWAPLQPMDALELLDIRYVDIV 619
Query: 965 VRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLL 1024
VRE A K LN M+D +L + QL Q L+HE Y +LL
Sbjct: 620 VREHAVKYLNGMTDYELKGCVLQLVQVLKHEPYHDSALFR-----------------FLL 662
Query: 1025 VHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLL 1084
SL + H F + SE T S S RY L+L L+ E K L
Sbjct: 663 RRSLQSPHMIGHYVFWYL-----VSEMENT----SVSERYGLLLEELIRRMPER--KVYL 711
Query: 1085 RQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVK 1144
RQ L L E A+ VK A + LP+ LD+
Sbjct: 712 RQLYLADQLFECAMRVKDAPKKDRIDCLREHLQGLRLPRRF---TLPINPAMECSGLDIG 768
Query: 1145 SCTYFSSNTLPLKINFIGTDNAVIP--AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDL 1202
C S PL + F P +FK GDDLRQD LQ++++MD+LW GL L
Sbjct: 769 KCKVMDSKKFPLWLVFRNYQEEGDPFYVIFKAGDDLRQDLFTLQLLELMDSLWKSCGLYL 828
Query: 1203 RMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWG-LTGSFKDKPIAEWLAKHNPSELEYQ 1261
++ + + T GMIE+V ++T+ I ++G +F+++P+ WL + N E +
Sbjct: 829 HIIPYGCITTGEGVGMIEVVLNSDTVANITRKYGGAQAAFREEPLMNWLRQFNRERDEVE 888
Query: 1262 RARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLV 1321
R NF S AGY+VATY+LGI DRHNDNIML+ G LFHIDFG FLG+ + KR
Sbjct: 889 RCLWNFICSVAGYTVATYVLGIGDRHNDNIMLRQDGTLFHIDFGHFLGNFKTKFGIKR-- 946
Query: 1322 YIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+ APF+ T VY++ G P + +FV+L C AFN+VR ++ LF L
Sbjct: 947 --ETAPFIFTPMYVYMLGGQSSPI--YLYFVDLACHAFNVVRRFGGTLMTLFML 996
>UniRef50_UPI0000498754 Cluster: phosphatidylinositol 3-kinase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: phosphatidylinositol
3-kinase - Entamoeba histolytica HM-1:IMSS
Length = 1352
Score = 218 bits (533), Expect = 8e-55
Identities = 147/499 (29%), Positives = 241/499 (48%), Gaps = 48/499 (9%)
Query: 888 LIEQGAYQRMPTECREVMWEKRQYLVQIPGA----LPLVLLAATNWYGDHREQLI--GLL 941
++ + + E +E++W RQ+++ +VLL + + +E + L+
Sbjct: 886 IVTTNLLKEIENEDKELIWRGRQFILNEETLHLHPSSIVLLCQSVPWNKPKEVKVFEQLI 945
Query: 942 RLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXX 1001
+ W K S + A+ LL F + +R+ A L E +D+ L ++ QL Q+L+ E
Sbjct: 946 QKWPKVSHIIALRLLHFSFANSFIRQYAVNCLVECNDEHLSTIMMQLIQSLKFEATPLSD 1005
Query: 1002 XXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSAS 1061
F+ L+ S +IP+
Sbjct: 1006 LAIFLIHRALNKRSTIGRIFFWLIKSELHIPETQR------------------------- 1040
Query: 1062 WRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXX 1121
R+ L+L A L++CG +T+++ QL LC+ S+ +
Sbjct: 1041 -RFALLLEAFLMVCGAQ--RTVIKNQL---DLCKKLTSLYTQQNQTWKTDINQLTKELNN 1094
Query: 1122 XXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPA--MFKVGDDLR 1179
Q T +P + ++C S PL + F D P +FK DDLR
Sbjct: 1095 IILPQITYVPFKSSLKFTKIVAENCKVLDSLRKPLFLTFKNEDPEGDPIYIIFKKDDDLR 1154
Query: 1180 QDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEW---G 1236
QD L+V+++M+ +W G D+R+ ++ L N+ GMIE+V +ET+ AIQ +
Sbjct: 1155 QDMFALKVLEVMNQMWQNEGYDMRLTCYECLAMGNAVGMIEVVLRSETIAAIQKKMYGGN 1214
Query: 1237 LTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTS 1296
++ +F++ P+ +WL N S+ E+ A+ NF SCAGY VATY+LG+ DRHNDNI+L +
Sbjct: 1215 VSAAFQEDPLYKWLKDKNTSDDEFLNAQQNFIYSCAGYCVATYVLGVGDRHNDNILLTPT 1274
Query: 1297 GHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCC 1356
GHL HIDFG LG+ + F FKR + APFVLT + VYV+ G + ++ F+ FV LCC
Sbjct: 1275 GHLVHIDFGHILGNVEKFKGFKR----ETAPFVLTKEFVYVMGG--KNSEGFRLFVNLCC 1328
Query: 1357 MAFNIVRAHHDHILDLFAL 1375
F I+R ++ +++LF +
Sbjct: 1329 DTFLILRKNYHGLVNLFTM 1347
>UniRef50_Q54S78 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1671
Score = 215 bits (524), Expect = 1e-53
Identities = 112/240 (46%), Positives = 156/240 (65%), Gaps = 15/240 (6%)
Query: 1141 LDVKSCTYFSSNTLPLKINFIGTD----NAVIPAMFKVGDDLRQDALVLQVIKIMDTLWL 1196
+DV C S TLPL ++ D N+ + +FK GDDLRQD LV+Q+I IMD +WL
Sbjct: 1381 IDVNGCKVKESKTLPLFLSIENYDPMGDNSFV--IFKAGDDLRQDQLVIQMINIMDKMWL 1438
Query: 1197 KAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWG-LTGSFKDKPIAEWLAKHNP 1255
G+DL+ +T++ + T +GMIE+V ++ T+ IQ + G +T +F + I++WL + NP
Sbjct: 1439 DDGIDLQTITYRCIATGPMEGMIEVVGDSITIAEIQKQQGGITAAFSETVISQWLKQENP 1498
Query: 1256 SELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFG 1315
SELEY A +NF SCAG V +Y+LGI DRHNDNIM+ SGHLFHID G+FLG+ Q +
Sbjct: 1499 SELEYSNAVENFIRSCAGCCVYSYILGIGDRHNDNIMITKSGHLFHIDHGRFLGNVQTWN 1558
Query: 1316 NFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
KR +RAPFV T+ VI GGE F++F +LC A+N +R H + IL+LF +
Sbjct: 1559 GIKR----ERAPFVFTNAFANVI-GGE---NNFKNFEDLCSRAYNTIRKHANVILNLFLM 1610
Score = 50.8 bits (116), Expect = 3e-04
Identities = 34/121 (28%), Positives = 65/121 (53%), Gaps = 6/121 (4%)
Query: 882 QSQLL--HLIEQGAYQRMPTECREVMWEKRQYLV-QIPGALPLVLLAATNWYGDHREQLI 938
Q+QL+ ++++ + E +E++W+ R Y Q+ ++ ++L+ W Q
Sbjct: 1069 QNQLIINSILKKDVLTDLKKEEKELIWKNRNYCKNQMNNSISKLILSVP-WNDSESVQEF 1127
Query: 939 G--LLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHET 996
L+ + +P++++ LL F D VR A + L +M+DDD+ LPQL QA++HE
Sbjct: 1128 YWLLMNCPQFENPIDSLELLSQSFLDRQVRNFAIQNLCKMNDDDITMYLPQLIQAIKHEP 1187
Query: 997 Y 997
+
Sbjct: 1188 H 1188
>UniRef50_P48736 Cluster: Phosphatidylinositol-4,5-bisphosphate
3-kinase catalytic subunit gamma isoform; n=30;
Euteleostomi|Rep: Phosphatidylinositol-4,5-bisphosphate
3-kinase catalytic subunit gamma isoform - Homo sapiens
(Human)
Length = 1102
Score = 215 bits (524), Expect = 1e-53
Identities = 182/678 (26%), Positives = 301/678 (44%), Gaps = 75/678 (11%)
Query: 725 FYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGD 784
F ++++ WL + + LP+ + L L ++ + S+ E+ PSS E++
Sbjct: 404 FTEEVLWNVWLEFS-IKIKDLPKGALLNLQIYCGKAPALSSKASAES--PSS-ESKGKVQ 459
Query: 785 VLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXX------X 838
+LY + L L D +L G YVL +W S
Sbjct: 460 LLY------YVNLLLIDHRFLLRRGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENS 513
Query: 839 XVVNIEIPLYAHT-GVKWTSGEEDKQKNISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRM 897
++I + Y H + D + + ++P+ + QL +I +
Sbjct: 514 MSISILLDNYCHPIALPKHQPTPDPEGDRVRAEMPN------QLRKQLEAIIATDPLNPL 567
Query: 898 PTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDH----REQLIGLLRLWEKPS-PLNA 952
E +E++W R ++ P A P L ++ W QL+ +W++ + +
Sbjct: 568 TAEDKELLWHFRYESLKHPKAYPK-LFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGL 626
Query: 953 MHLLLPC-FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXX 1011
LL C F D VR A + L + DDD+ L QL QA++ E Y
Sbjct: 627 TMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGL 686
Query: 1012 XXXXXXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRAL 1071
FW L I Q+ H + R+ ++L A
Sbjct: 687 RNKRIGHFLFWFL---RSEIAQSRHYQ-----------------------QRFAVILEAY 720
Query: 1072 LVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALP 1131
L CG + +Q +++ L ++ + +K Q + LP
Sbjct: 721 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP 780
Query: 1132 LALHKYVHD-------LDVKSCTYFSSNTLPLKINFIGTD-----NAVIPAMFKVGDDLR 1179
+ + +D L ++ C +S PL + F D N I +FK GDDLR
Sbjct: 781 ESF-RVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLR 839
Query: 1180 QDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEW-GLT 1238
QD L+LQ+++IM+++W LDL ++ + + T + GMIEIV +A T+ IQ G T
Sbjct: 840 QDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNT 899
Query: 1239 GSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGH 1298
G+FKD+ + WL + +P+E ++Q A + F SCAGY VAT++LGI DRHNDNIM+ +G+
Sbjct: 900 GAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGN 959
Query: 1299 LFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI-NGGERPTQRFQHFVELCCM 1357
LFHIDFG LG+ + F + +R PFVLT D ++V+ G++ + FQ F ++C
Sbjct: 960 LFHIDFGHILGNYKSFLGINK----ERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVK 1015
Query: 1358 AFNIVRAHHDHILDLFAL 1375
A+ +R H + ++ LF++
Sbjct: 1016 AYLALRHHTNLLIILFSM 1033
>UniRef50_UPI0000E48471 Cluster: PREDICTED: similar to
phosphoinositide-3-kinase, catalytic, beta polypeptide;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to phosphoinositide-3-kinase, catalytic, beta
polypeptide - Strongylocentrotus purpuratus
Length = 1049
Score = 210 bits (513), Expect = 2e-52
Identities = 115/253 (45%), Positives = 156/253 (61%), Gaps = 12/253 (4%)
Query: 1131 PLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVI 1188
PLA + L + C + SS PL + F D + +FK GDDLRQD L LQV+
Sbjct: 740 PLAPSNKLKCLRLNKCKFMSSKMRPLWLVFENDDPIGDDVYILFKNGDDLRQDMLTLQVM 799
Query: 1189 KIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWG----LTGSFKDK 1244
+IMD +W + GLDLR++ ++ L T G+IE+VT ++T+ IQ + G LT +F+
Sbjct: 800 QIMDNIWQEEGLDLRIIPYKTLATGPKVGLIEVVTNSDTIANIQKQHGSVNVLTAAFQKA 859
Query: 1245 PIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDF 1304
+ EWL KH+P+E +A ++FT SCAGY VATY+LGI DRHNDNIM+K SG LFHIDF
Sbjct: 860 ALFEWLKKHSPTEEMLNKAIEDFTFSCAGYCVATYVLGIGDRHNDNIMVKESGQLFHIDF 919
Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGE--RPTQRFQHFVELCCMAFNIV 1362
G FLG+ + KR +R PFVLTHD V+VI G+ T F F C AF I+
Sbjct: 920 GHFLGNYKRKFGLKR----ERVPFVLTHDFVHVITRGKGASTTTEFDSFRRCCEEAFMIL 975
Query: 1363 RAHHDHILDLFAL 1375
R + +++LFA+
Sbjct: 976 RRRGNLLINLFAM 988
Score = 44.8 bits (101), Expect = 0.018
Identities = 43/203 (21%), Positives = 83/203 (40%), Gaps = 10/203 (4%)
Query: 739 DLPVNTLPRESRLVLTLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQ 798
D+ V+ LPR ++L + ++ + I + + L V + W L
Sbjct: 406 DINVSNLPRMAKLCIMVYTLGNKKIVKTTSGAQLDQGKAKKKFPRKDL---VPIAWVNLT 462
Query: 799 LFDFDGMLSSGNYVLPLWPTSCD-RRXXXXXXXXXXXXXXXXVVNIEIPLYAHTGVKWTS 857
FD+ L SG + L +WP S D + + Y V + +
Sbjct: 463 FFDYRSQLRSGPHKLFMWPASEDIDLNPLGHCESNPSKDDTTCIEVSFEQYRQGSVSYPT 522
Query: 858 GEE--DKQKNISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQ-YLVQ 914
++ ++ +I+ D F++ +L ++E+ + + + RE +W RQ Q
Sbjct: 523 FDKVIERAADIARSDDNPFETPSEQALEELRQIVEKDPLEPLSEQEREDLWLARQDCRDQ 582
Query: 915 IPGALPLVLLAATNWYGDHREQL 937
+P ALP LL +W +HR+++
Sbjct: 583 LPHALPR-LLKCVHW--NHRDEV 602
>UniRef50_A0DT78 Cluster: Chromosome undetermined scaffold_62, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_62, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1176
Score = 210 bits (512), Expect = 3e-52
Identities = 113/322 (35%), Positives = 180/322 (55%), Gaps = 16/322 (4%)
Query: 1063 RYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAK---EXXXXXXXXXXXXXX 1119
RY + L L++ICG+ +T++++ L L E ++ +K + E
Sbjct: 801 RYFIWLEQLIMICGQ-FRETIVKEVRLNNLLIESSLKIKSKQVGTEMQQKTDALKKELQY 859
Query: 1120 XXXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAV------IPAMFK 1173
QP P+ + D+ C +S LPLK+ ++ + +FK
Sbjct: 860 ITQNVVQPFTFPIDARMQIASFDIDQCKVLNSKKLPLKLYLKSYQKSINQQINQLQVIFK 919
Query: 1174 VGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQT 1233
GDDL+QD L LQ+IKI+DT+WL +GLD +M ++ + T + GMIE+V ++ + I
Sbjct: 920 NGDDLKQDMLTLQIIKIIDTIWLDSGLDFKMKPYKVIATDDQVGMIEVVLDSLNISEIHD 979
Query: 1234 EWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML 1293
+ G G+F +K + +L + N + + R++D F SCAGY VATY+LGI DRH+ NIM+
Sbjct: 980 KIGAFGAFDEKALINYLHQQNQNAEDLNRSKDIFLRSCAGYCVATYVLGIGDRHSGNIMI 1039
Query: 1294 KTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVE 1353
K+SGH+FHIDFG FLG+ ++ R +RA FVLT +M+ V+ G + T F+ F +
Sbjct: 1040 KSSGHIFHIDFGHFLGNFKIKFGINR----ERAKFVLTPEMLTVMGGQDSET--FRQFEK 1093
Query: 1354 LCCMAFNIVRAHHDHILDLFAL 1375
C A+N++R H ++DLF +
Sbjct: 1094 HCLDAYNLIRKHGRWLVDLFLM 1115
Score = 41.5 bits (93), Expect = 0.17
Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 2/88 (2%)
Query: 909 RQYLVQIPGALPLVLLAATNWYGDHR-EQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRE 967
R + +P AL L L A NW + + +++ W P A+ L+ FPD VR
Sbjct: 673 RHHYKTLPYALQL-FLKAVNWADPKQVREAHQMIKEWIPLPPQIALILMDSHFPDEIVRL 731
Query: 968 TAAKLLNEMSDDDLCRVLPQLTQALRHE 995
A ++ +SDD+L L QL+QAL+ E
Sbjct: 732 YAVDRISLLSDDELSLYLLQLSQALQFE 759
>UniRef50_UPI0000D57007 Cluster: PREDICTED: similar to CG4141-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG4141-PA, isoform A - Tribolium castaneum
Length = 996
Score = 204 bits (497), Expect = 2e-50
Identities = 105/208 (50%), Positives = 132/208 (63%), Gaps = 7/208 (3%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK GDDLRQD L LQ++KIMD LW GLDLR+ + + + GMIE+V AET+
Sbjct: 729 IFKDGDDLRQDMLTLQMLKIMDRLWKSEGLDLRLSPYNCISLGDRAGMIEVVLNAETIAN 788
Query: 1231 IQTEWGL---TGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287
IQ + G+ T +F+ I WL HNP+E +A + FT SCAGY VATY+LG+ DRH
Sbjct: 789 IQKDKGVFSATSAFRKGSILAWLRDHNPTESALNKAINEFTLSCAGYCVATYVLGVADRH 848
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
+DNIM+K SG LFHIDFG LG + KR +R PFVLTHD YVIN G++ T
Sbjct: 849 SDNIMVKKSGQLFHIDFGHILGHFKEKFGIKR----ERVPFVLTHDFEYVINKGQKTTLE 904
Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375
F+ F E C AF I+R H IL L A+
Sbjct: 905 FKIFQEYCEKAFVILRKHGSLILSLCAM 932
Score = 58.8 bits (136), Expect = 1e-06
Identities = 39/100 (39%), Positives = 56/100 (56%), Gaps = 7/100 (7%)
Query: 902 REVMWEKRQYLV-QIPGALPLVLLAATNWYGDHRE---QLIGLLRLWEKPSPLNAMHLLL 957
R+ +W + Y Q P LP LL++ +W D RE + LL+ W K P A+ LL
Sbjct: 485 RKNIWLLKDYWKKQNPEVLPK-LLSSIDW--DTREVVSDVAALLKDWPKLPPEKALELLD 541
Query: 958 PCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
+PD VR A + L+++SD+DL L QL QA++HE Y
Sbjct: 542 YAYPDQRVRSFAVECLDDVSDEDLLLYLLQLVQAIKHEMY 581
>UniRef50_P91634 Cluster: Phosphoinositide 3-kinase, Dp110; n=6;
Sophophora|Rep: Phosphoinositide 3-kinase, Dp110 -
Drosophila melanogaster (Fruit fly)
Length = 1088
Score = 202 bits (494), Expect = 4e-50
Identities = 110/237 (46%), Positives = 144/237 (60%), Gaps = 11/237 (4%)
Query: 1146 CTYFSSNTLPLKINFIGTD-NAV-IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203
C S PL + F D NA + +FK GDDLRQD L LQ++++MD LW + G+D R
Sbjct: 792 CKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFR 851
Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHNPSELEY 1260
M + + S GMIE+V AET+ IQ E G+ T FK + WL +HN +
Sbjct: 852 MNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKL 911
Query: 1261 QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRL 1320
+A + FT SCAGY VATY+LG+ DRH+DNIM+K +G LFHIDFG LG + +R
Sbjct: 912 NKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRR- 970
Query: 1321 VYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+R PFVLTHD VYVIN G +R ++ F HF ELC AF ++R H IL LF++
Sbjct: 971 ---ERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSM 1024
Score = 64.9 bits (151), Expect = 2e-08
Identities = 74/314 (23%), Positives = 129/314 (41%), Gaps = 28/314 (8%)
Query: 699 HAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGR 758
H +YHG + L R T + G + +F+ + D+ + LPR +RL + +
Sbjct: 371 HVCLYHGDKKLCAQRSTDSPN----GNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEV 426
Query: 759 TQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPT 818
T+ + + N DV Y + L W +FD +L +G + L W
Sbjct: 427 TKMSRSKKSSNNKDIALK-------DVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTY 479
Query: 819 SCDRRXXXXXXXXXXXX-----XXXXVVNIEIPLYAHTG-VKWTSGE-------EDKQKN 865
+ D + +V++ L + TG V++ S E + +Q N
Sbjct: 480 ADDIQSVEVFHPLGTIEPNPRKEECALVDLTF-LSSGTGTVRYPSEEVVLQYAADREQVN 538
Query: 866 ISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLV-QIPGALPLVLL 924
+ L + + + + M + R +WE+R ++ ++P L +LL
Sbjct: 539 RLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELS-ILL 597
Query: 925 AATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983
W D + LL+ W S ++ LL +PD AVR A + L+ + D+DL
Sbjct: 598 HCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLL 657
Query: 984 VLPQLTQALRHETY 997
L QL QA++HE+Y
Sbjct: 658 YLLQLVQAIKHESY 671
>UniRef50_Q241V8 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 1249
Score = 202 bits (492), Expect = 8e-50
Identities = 116/316 (36%), Positives = 173/316 (54%), Gaps = 11/316 (3%)
Query: 1063 RYTLMLRALLVICGENLNKTLLRQQL--LVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXX 1120
RY L++ +L++CG N+ +++ + +K + + KE
Sbjct: 881 RYFLIIEQMLMLCGSFRNELVVQVGVNDQIKKIGQEIQDESLFKEHTLLVPLTRKKLSEI 940
Query: 1121 XXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQ 1180
AL + V ++ C +S +PL I ++ I +FK GDD+RQ
Sbjct: 941 KLPEEFSFALDSRMQ--VQRFEIDDCKCMNSKKVPLWIATKSKEDENINILFKCGDDIRQ 998
Query: 1181 DALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWG-LTG 1239
D L LQ++KIMD +WL AG D RM ++ + T + GMIEIV +ET I +++G + G
Sbjct: 999 DQLTLQLLKIMDKIWLDAGHDFRMKPYKVITTDDQVGMIEIVNNSETTAKIHSKYGGVLG 1058
Query: 1240 SFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHL 1299
+F++ I ++L N ++ A DNF SCAGY VATY+LGI DRH DNIML +GHL
Sbjct: 1059 AFRNNTIWQYLKDKNMDPHSFEIATDNFLRSCAGYCVATYILGIGDRHADNIMLSQTGHL 1118
Query: 1300 FHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAF 1359
FHIDFG FLG+ + KR +RAPFVLT +M +V+ G + F+ F E C A+
Sbjct: 1119 FHIDFGHFLGNFKTKFGIKR----ERAPFVLTKEMAFVMGG--KDGNLFRKFEEYCTQAY 1172
Query: 1360 NIVRAHHDHILDLFAL 1375
N+VR + I+++F L
Sbjct: 1173 NLVRKSGNFIINIFLL 1188
Score = 36.7 bits (81), Expect = 4.9
Identities = 21/76 (27%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 922 VLLAATNWYGDHR-EQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDD 980
+ L A +W + ++ I +L+ W SP +A+ LL + +VR A + ++ SDD+
Sbjct: 765 IFLFAIDWLDPEQVKEAILMLKQWTLLSPEDALPLLDANMANESVRLYAVERVSTFSDDE 824
Query: 981 LCRVLPQLTQALRHET 996
+ + +LTQ++ +E+
Sbjct: 825 IALYMLELTQSILYES 840
>UniRef50_Q22H25 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 1559
Score = 201 bits (491), Expect = 1e-49
Identities = 151/478 (31%), Positives = 227/478 (47%), Gaps = 51/478 (10%)
Query: 909 RQYLVQIPGALPLVLLAATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRE 967
R + I AL + L A +W +H + LL+ W+ P + L D +R
Sbjct: 1062 RNHFKSIHQALD-IFLCAVDWSNPEHIRETYNLLKQWKSPPCEECITFLDAHHADEVIRL 1120
Query: 968 TAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHS 1027
+ +++M+DD++ + +L QAL E LL S
Sbjct: 1121 YGVERISKMADDEIKLYMIELVQALMFENNHYSPIQEL-----------------LLERS 1163
Query: 1028 LPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQ 1087
L N H+ F + + + ++ E RY L+L LL++ GE ++ LL++
Sbjct: 1164 LLNPFVVGHELFWSLKSQLHLKQSYE---------RYALVLEQLLMLSGEYRSE-LLKEV 1213
Query: 1088 LLVKSLCEMAVSVKC------AKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDL 1141
+ L +A +K AKE Q L + ++D
Sbjct: 1214 EVNNELKNIARKIKVQKTNEQAKEVLEKELKRLINNKYKQKGEGQEFTLAIDNRLQLNDF 1273
Query: 1142 DVKSCTYFSSNTLPLKINFIGTDNAV-IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGL 1200
D K C + +S PL + +N MFK GDDLRQD L LQ+I+IMD +WL L
Sbjct: 1274 DTKKCKFMNSKKKPLWLVMKNAENQKEFSIMFKDGDDLRQDILTLQLIRIMDKIWLDNNL 1333
Query: 1201 DLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLT-GSFKDKPIAEWLAKHNPSELE 1259
DLRM + + T + GM+EIV ++T AI + G + I ++L KHN +
Sbjct: 1334 DLRMKPYNVVATLDQVGMLEIVQNSQTTAAIHKQNNQRFGCLMKESIQKYLKKHNKN--- 1390
Query: 1260 YQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR 1319
Y++AR NF SCAGY VATY+LGI DRH+DNIM+ GH FHIDFG FL GNFK+
Sbjct: 1391 YEQARANFRTSCAGYCVATYILGIGDRHSDNIMITKEGHFFHIDFGHFL------GNFKK 1444
Query: 1320 LVYI--DRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
I +R+PFV T M YV+ + + F+ + CC A+N++R H + +++F +
Sbjct: 1445 KFGINRERSPFVFTRVMEYVMLEKQEDYEAFEKY---CCQAYNLIRKHGNFFINIFRM 1499
>UniRef50_Q17GT9 Cluster: Phosphatidylinositol 3-kinase catalytic
subunit alpha, beta, delta; n=2; Endopterygota|Rep:
Phosphatidylinositol 3-kinase catalytic subunit alpha,
beta, delta - Aedes aegypti (Yellowfever mosquito)
Length = 1055
Score = 200 bits (488), Expect = 2e-49
Identities = 125/324 (38%), Positives = 169/324 (52%), Gaps = 12/324 (3%)
Query: 1059 SASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXX 1118
S R++L+L A L E+++ LL+Q ++ L + VK +
Sbjct: 673 SVQVRFSLILEAYLKGSQEHIS-ILLKQMQCLRKLQHGSELVKKGNKEKGKSLLMDYLQD 731
Query: 1119 XXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAV--IPAMFKVGD 1176
PL + + C S PL I + +D+ I +FK GD
Sbjct: 732 KPVGDALSDVISPLNPSFRCKTVRKEKCKVMDSKMRPLWIVYQNSDSNGDDINMIFKNGD 791
Query: 1177 DLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWG 1236
DLRQD L LQ+++IMD +W G D RM + + T G+IE+V AET+ IQ E G
Sbjct: 792 DLRQDMLTLQMLRIMDRIWKSHGYDFRMNPYSCISTDRRLGIIEVVLNAETIANIQKERG 851
Query: 1237 L---TGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML 1293
+ T FK + WL +HN +E +A FT SCAGY VATY+LG+ DRH+DNIM+
Sbjct: 852 MFSATSPFKKGSLLTWLKEHNTTEEMLAKAIQEFTLSCAGYCVATYVLGVGDRHSDNIMV 911
Query: 1294 KTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGG--ERPTQRFQHF 1351
K +G LFHIDFG LG + F+R +R PFVLTHD VYVIN G +R + F+ F
Sbjct: 912 KKTGQLFHIDFGHILGHFKEKFGFRR----ERVPFVLTHDFVYVINNGRTDREAKEFRQF 967
Query: 1352 VELCCMAFNIVRAHHDHILDLFAL 1375
LC AF I+R H IL LFA+
Sbjct: 968 QHLCEEAFLILRKHGCLILSLFAM 991
Score = 54.4 bits (125), Expect = 2e-05
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 5/116 (4%)
Query: 885 LLHLIEQGAYQRMPTECREVMWEKRQYLVQI-PGALPLVLLAATNWYGDHRE--QLIGLL 941
LL + M + R +W KR+ + + P LP LL W D E +++ LL
Sbjct: 525 LLPYMHNDKLNDMHEQDRNAIWAKRRECMTLEPDGLPC-LLYCVEW-NDRNEVAEIVSLL 582
Query: 942 RLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
+ W A+ LL + D VR A K L + DD+L L QL QA++HE+Y
Sbjct: 583 QEWPILPVERALELLDYAYADQYVRRYAVKCLRTIQDDELLLYLLQLVQAMKHESY 638
>UniRef50_A7S2J3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1041
Score = 199 bits (485), Expect = 5e-49
Identities = 109/249 (43%), Positives = 145/249 (58%), Gaps = 8/249 (3%)
Query: 1131 PLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPA--MFKVGDDLRQDALVLQVI 1188
PL + L V +C Y S PL ++F D P +FK GDDLRQD L LQ+I
Sbjct: 734 PLNPSYRLKQLKVDNCKYMDSKMRPLWLDFENFDELGEPVKIIFKSGDDLRQDMLTLQLI 793
Query: 1189 KIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEW--GLTGSFKDKPI 1246
+IMD LW K GLDL M+ + L T + GMIE+VT +ET+ IQ + +TG+F I
Sbjct: 794 RIMDRLWKKDGLDLEMIPYGCLSTGDHVGMIEVVTNSETIAKIQMKQMGAITGAFNKTCI 853
Query: 1247 AEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGK 1306
+WLA N S+ A F SCAGY VATY+LG+ DRH+DNIM+ +G LFHIDFG
Sbjct: 854 LDWLADRNGSKEALVEATHRFMLSCAGYCVATYVLGVGDRHSDNIMVHENGQLFHIDFGH 913
Query: 1307 FLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHH 1366
FLG+ + +R +R PFVLT V+VI G T+ FQ F +C AF ++R
Sbjct: 914 FLGNFKNKFGIRR----ERVPFVLTDHFVHVITRGNDNTEGFQEFRRICEQAFLVLRRRG 969
Query: 1367 DHILDLFAL 1375
+++LF +
Sbjct: 970 SLLINLFVM 978
Score = 63.7 bits (148), Expect = 4e-08
Identities = 80/334 (23%), Positives = 128/334 (38%), Gaps = 30/334 (8%)
Query: 702 IYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGRTQR 761
IYHG L ++ T+ G P +++ ++NL L V +PR +RL L L G +
Sbjct: 350 IYHGNEVLSDIKQTKPQS----GNKP--LWNEFINLNIL-VCDIPRMARLCLVLFGVYVK 402
Query: 762 TIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWP---T 818
++ +N + + L W + LFDF G L G + WP T
Sbjct: 403 AA-ARRKKKN---------------LDYIPLAWVNVTLFDFRGNLRQGPLTIHAWPVPET 446
Query: 819 SCDRRXXXXXXXXXXXXXXXXVVNIEIPLYAHTGVKWTSGEEDKQKNISLKDLPSFDSLD 878
D + IE YA+ V + + ++ Q D F
Sbjct: 447 MPDLLNPIGTVVSNINTSTSPCLVIEFQRYANN-VVYPAYDKILQLAAETTDQEIFKKTG 505
Query: 879 GHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQI-PGALPLVLLAATNWY-GDHREQ 936
+ QL +I++ + +E +W R P +L LL+ W + Q
Sbjct: 506 DNELEQLRQVIDREPLAPIFELDKEFVWRARMECRDYYPHSLGR-LLSCVKWNCKEDVAQ 564
Query: 937 LIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHET 996
+ LL++W + P A+ LL + D VRE A + + +M D DL + QL Q L++E+
Sbjct: 565 MQVLLQIWPEMHPELALELLDCNYADQKVREFAVRCIEKMGDSDLMHYMLQLVQVLKYES 624
Query: 997 YXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPN 1030
Y FWLL + N
Sbjct: 625 YLDCELARFLLKRTLNNQNLGHELFWLLRAEMHN 658
>UniRef50_Q7QEJ7 Cluster: ENSANGP00000020426; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020426 - Anopheles gambiae
str. PEST
Length = 968
Score = 198 bits (483), Expect = 1e-48
Identities = 110/237 (46%), Positives = 140/237 (59%), Gaps = 11/237 (4%)
Query: 1146 CTYFSSNTLPLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203
C S PL I + +D I +FK GDDLRQD L LQ+++IMD +W G D R
Sbjct: 672 CKVMDSKMRPLWIVYENSDANGDDIHMIFKNGDDLRQDMLTLQMLRIMDRIWKSHGYDFR 731
Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHNPSELEY 1260
M + + T + G+IE+V AET+ IQ E G+ T FK + WL +HN +E
Sbjct: 732 MNPYSCISTDHKLGLIEVVLNAETIANIQKERGMFSATSPFKKGSLLAWLREHNGTEDLL 791
Query: 1261 QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRL 1320
+A FT SCAGY VATY+LG+ DRH+DNIM+K +G LFHIDFG LG + F+R
Sbjct: 792 AKAIQEFTLSCAGYCVATYVLGVADRHSDNIMVKKTGQLFHIDFGHILGHFKEKFGFRR- 850
Query: 1321 VYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+R PFVLTHD VYVIN G +R Q F F LC AF I+R H IL LF++
Sbjct: 851 ---ERVPFVLTHDFVYVINNGRTDREAQEFCRFQTLCEEAFLILRQHGCLILSLFSM 904
Score = 58.0 bits (134), Expect = 2e-06
Identities = 36/98 (36%), Positives = 50/98 (51%), Gaps = 3/98 (3%)
Query: 902 REVMWEKR-QYLVQIPGALPLVLLAATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPC 959
R +W KR + + Q+P LP LL W D +++ LL+ W K A+ LL
Sbjct: 457 RNAIWAKRRECMKQMPQGLPC-LLYCVEWNNRDEVSEIVSLLQEWPKLLVERALELLDYA 515
Query: 960 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
+ D VR A L + DD+L L QL QAL+HE+Y
Sbjct: 516 YADKYVRRYAVDCLRTIEDDELLLYLLQLVQALKHESY 553
>UniRef50_Q237I3 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 1200
Score = 198 bits (483), Expect = 1e-48
Identities = 101/218 (46%), Positives = 140/218 (64%), Gaps = 11/218 (5%)
Query: 1161 IGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIE 1220
I ++ + +FK GDD+RQD L LQ++KIMD +WL AG D RM ++ + T + GMIE
Sbjct: 931 ISENDLEMKILFKRGDDIRQDQLTLQLLKIMDKIWLDAGQDFRMKPYKVITTGDQVGMIE 990
Query: 1221 IVTEAETLRAI-QTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATY 1279
+V AET I + E G G+ K+ + +L KHNP + + A +NF SCAGY VATY
Sbjct: 991 VVVNAETTARIHKQEGGGLGALKEDTLKNYLQKHNPDKENLKSATENFIRSCAGYCVATY 1050
Query: 1280 LLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYID--RAPFVLTHDMVYV 1337
+LGI DRH DNIML +GHLFHIDFG FL GNFK+ + ID RAPFV T +M +V
Sbjct: 1051 ILGIGDRHPDNIMLSQTGHLFHIDFGHFL------GNFKKKLGIDRERAPFVFTEEMAFV 1104
Query: 1338 INGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+ G E + F++F + C A+N++R + I+++F L
Sbjct: 1105 MGGKE--SADFKNFTDYCTQAYNLIRKQGNFIINIFLL 1140
Score = 37.5 bits (83), Expect = 2.8
Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 900 ECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHR-EQLIGLLRLWEKPSPLNAMHLLLP 958
E + ++ R + + AL + LLA +W + ++ I +L+ W P +A+ LL
Sbjct: 654 EDKHILMISRNHYKTLTQALQVFLLAV-DWLDPEQVKEAILMLKKWTPLQPEDALPLLDA 712
Query: 959 CFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
+ VR A + ++ SDD++ + +LTQ L +E
Sbjct: 713 HISNEIVRLYAVERISTFSDDEIALYMLELTQLLLYE 749
>UniRef50_Q5SR50 Cluster: Phosphoinositide-3-kinase, catalytic, delta
polypeptide; n=7; Eutheria|Rep:
Phosphoinositide-3-kinase, catalytic, delta polypeptide -
Homo sapiens (Human)
Length = 1068
Score = 195 bits (475), Expect = 9e-48
Identities = 107/252 (42%), Positives = 148/252 (58%), Gaps = 12/252 (4%)
Query: 1131 PLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTD---NAVIPAMFKVGDDLRQDALVLQV 1187
PL + ++ V+ CT+ S PL I + + + +FK GDDLRQD L LQ+
Sbjct: 758 PLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQM 817
Query: 1188 IKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ---TEWGLTGSFKDK 1244
I++MD LW + GLDLRM + LPT + G+IE+V ++T+ IQ + T +F
Sbjct: 818 IQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKD 877
Query: 1245 PIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDF 1304
+ WL NP E RA + FT SCAGY VATY+LGI DRH+DNIM++ SG LFHIDF
Sbjct: 878 ALLNWLKSKNPGEA-LDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDF 936
Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGE-RPTQRFQHFVELCCMAFNIVR 1363
G FLG+ + R +R PF+LT+D V+VI G+ +++F+ F C A+ I+R
Sbjct: 937 GHFLGNFKTKFGINR----ERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILR 992
Query: 1364 AHHDHILDLFAL 1375
H L LFAL
Sbjct: 993 RHGLLFLHLFAL 1004
Score = 57.2 bits (132), Expect = 3e-06
Identities = 39/119 (32%), Positives = 65/119 (54%), Gaps = 5/119 (4%)
Query: 882 QSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQ-IPGALPLVLLAATNWYGDHRE--QLI 938
Q QL ++E+ + ++++W+ R + + P AL +LL T W H + Q++
Sbjct: 532 QLQLREILERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLV-TKW-NKHEDVAQML 589
Query: 939 GLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
LL W + L+A+ LL FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 590 YLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 648
Score = 36.3 bits (80), Expect = 6.4
Identities = 45/181 (24%), Positives = 74/181 (40%), Gaps = 28/181 (15%)
Query: 651 FRLADAHYQAPANPAKAVPAHTISETTLFCIEAVHCLPLCWSH----DEYM---FHAQIY 703
+ L Q P +PA S +L+ +E + L DE M A ++
Sbjct: 254 YPLCQFQVQKPRAKPPPIPAKKPSSVSLWSLEQPFRIELIQGSKVNADERMKLVVQAGLF 313
Query: 704 HGTRPL-KTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGRTQRT 762
HG L KT+ ++ S + R+ FD +N+ DLP R +RL L+
Sbjct: 314 HGNEMLCKTVSSSEVSVCSEPVWKQRLEFD--INICDLP-----RMARLCFALYA----V 362
Query: 763 IDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPTSCDR 822
I+ ++ S++A+ + WA L LFD+ L +G L +WP+ D
Sbjct: 363 IEKAKKARSTKKKSKKAD---------CPIAWANLMLFDYKDQLKTGERCLYMWPSVPDE 413
Query: 823 R 823
+
Sbjct: 414 K 414
>UniRef50_UPI00015B4B40 Cluster: PREDICTED: similar to
phosphatidylinositol 3-kinase catalytic subunit alpha,
beta, delta; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to phosphatidylinositol 3-kinase catalytic
subunit alpha, beta, delta - Nasonia vitripennis
Length = 1103
Score = 193 bits (471), Expect = 3e-47
Identities = 108/244 (44%), Positives = 140/244 (57%), Gaps = 12/244 (4%)
Query: 1140 DLDVKSCTYFSSNTLPLKINFIGTDNAV--IPAMFKVGDDLRQDALVLQVIKIMDTLWLK 1197
++ V C S PL + F D I + K GDDLRQD L LQ+++IMD LW
Sbjct: 799 NIKVDKCRVMDSKMRPLCLAFQNLDQYGDDIYLILKHGDDLRQDMLTLQMLRIMDKLWKN 858
Query: 1198 AGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL---TGSFKDKPIAEWLAKHN 1254
GLDLRM + + T N G+IE+V A+T+ IQ E G T +F+ + WL HN
Sbjct: 859 EGLDLRMNPYGCISTDNRVGLIEVVLNADTIANIQKEKGTFPATAAFRRGSLLAWLKDHN 918
Query: 1255 PSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMF 1314
SE +A + FT SCAGY VATY+LGI DRH+DNIM+K +G LFH+DFG LG +
Sbjct: 919 HSESTLNKAIEEFTLSCAGYCVATYVLGIADRHSDNIMVKKTGQLFHVDFGHILGHFKEK 978
Query: 1315 GNFKRLVYIDRAPFVLTHDMVYVINGGER---PTQRFQHFVELCCMAFNIVRAHHDHILD 1371
+R +R PFVLT+D V+VIN G+ FQ F C AF ++R H IL
Sbjct: 979 FGIRR----ERVPFVLTNDFVHVINKGQTKKGQALEFQRFQNYCEQAFLVLRRHGSLILS 1034
Query: 1372 LFAL 1375
LFA+
Sbjct: 1035 LFAM 1038
Score = 64.1 bits (149), Expect = 3e-08
Identities = 71/279 (25%), Positives = 112/279 (40%), Gaps = 32/279 (11%)
Query: 739 DLPVNTLPRESRLVLTLH--GRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAA 796
D+ V +PR +RL L+ G+T + I S+ ++S QE Y L WA
Sbjct: 417 DIKVRDIPRNTRLCCVLYEIGKTSKGIKSRKLVKDS---KQE--------YFINPLCWAN 465
Query: 797 LQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXXV-----VNIEIPLYAHT 851
++DF L +G L W + D + + + + P Y
Sbjct: 466 TTIYDFKSQLKTGAMTLYTWAYAEDIQNEDLLHPLGTVVSNPHIDRAAALMLTFPSYTRD 525
Query: 852 G----------VKWTSGEEDKQKNISLKDLPSFDSLD-GHTQSQLLHLIEQGAYQRMPTE 900
V++ + + ++N + D S D H QL L ++ + +
Sbjct: 526 QIILYPSPEKMVEFATKLSESRENSAEFDPTSVSDSDLQHHIDQLQLLADRDPLHELHEQ 585
Query: 901 CREVMWEKRQYLVQIPGALPLVLLAATNWYGDHRE--QLIGLLRLWEKPSPLNAMHLLLP 958
R+ +W RQ + + LL W DH+E + L+ W K A+ LL
Sbjct: 586 ERKTIWSLRQQCIMKVPTILTKLLQCVEW-NDHKEVSEATSLVLRWPKLPVERALELLDY 644
Query: 959 CFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
+ D VR A K L ++SD+DL L QL QAL+HE Y
Sbjct: 645 AYADQTVRSFAVKCLKDVSDEDLSLFLLQLVQALKHENY 683
>UniRef50_A0D2V1 Cluster: Chromosome undetermined scaffold_35, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_35, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1447
Score = 193 bits (471), Expect = 3e-47
Identities = 96/217 (44%), Positives = 135/217 (62%), Gaps = 6/217 (2%)
Query: 1159 NFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGM 1218
N + ++ MFK GDD+RQD L LQ+IKIMD +WL AGLD RM ++ + T ++ GM
Sbjct: 1175 NIDSKQSTLLKIMFKTGDDIRQDMLTLQLIKIMDKIWLDAGLDFRMKPYKTISTQDNVGM 1234
Query: 1219 IEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVAT 1278
IE+VT + T+ I + G+ G+F+ K I L N ++ A DNF SCAGY VAT
Sbjct: 1235 IEVVTNSLTIEKIHGDAGVMGAFQQKTIWNHLKTKNTEPQSFETATDNFLRSCAGYCVAT 1294
Query: 1279 YLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI 1338
Y+LGI DRH+ NIM+ +GHLFHIDFG FLG+ + KR +R FVLT +M +V+
Sbjct: 1295 YVLGIGDRHSGNIMITDTGHLFHIDFGHFLGNFKQKFGIKR----ERTKFVLTEEMAFVM 1350
Query: 1339 NGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
G R F+ F + C A+N+VR H ++++F +
Sbjct: 1351 GG--RDGDLFKKFQQDCTNAYNLVRKHGHFLINIFLM 1385
Score = 41.1 bits (92), Expect = 0.23
Identities = 49/193 (25%), Positives = 82/193 (42%), Gaps = 27/193 (13%)
Query: 909 RQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRET 968
R + +P AL + L+A + + +++LW P +A+ LL F D VR
Sbjct: 898 RNHYKTLPYALQIFLMAIEWDDPEQVREAHNMIKLWTPLPPEDALPLLDAPFADETVRLY 957
Query: 969 AAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSL 1028
A + ++ +SDD+L + +LTQ L E + LL SL
Sbjct: 958 AVERVSILSDDELQLYMLELTQCLMFEKHLFNPLAE-----------------MLLERSL 1000
Query: 1029 PNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQL 1088
N H+ F + + + + E RY+L+L LL++CGE + L+ + L
Sbjct: 1001 QNPWVVGHELFWLLKAQLHVRPSYE---------RYSLLLEQLLMLCGE-FRQQLMNEVL 1050
Query: 1089 LVKSLCEMAVSVK 1101
+ L +A VK
Sbjct: 1051 VDNELYNIAQKVK 1063
>UniRef50_UPI000049A3E6 Cluster: phosphatidylinositol 3-kinase; n=3;
Entamoeba histolytica HM-1:IMSS|Rep: phosphatidylinositol
3-kinase - Entamoeba histolytica HM-1:IMSS
Length = 1066
Score = 193 bits (470), Expect = 4e-47
Identities = 159/485 (32%), Positives = 229/485 (47%), Gaps = 47/485 (9%)
Query: 901 CREVMWEKRQYLVQI--PGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLP 958
CR ++W+ R YLV+ PG+L ++ A +L LL W P +A+ LL
Sbjct: 558 CR-LLWKYR-YLVEKTKPGSLARLVSAVDFTQQSEVLELHRLLNKWPLLEPTHALELLDF 615
Query: 959 CFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXX 1018
FPD VR A K L+ M D +L LPQL QAL+ E +
Sbjct: 616 RFPDEQVRLFALKCLDAMKDYELVNFLPQLVQALKFELHHQSNLA--------------- 660
Query: 1019 XXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGEN 1078
++LL +L N HQ F + E + +N T+ RY ++L A L C E+
Sbjct: 661 --YFLLRRALRNKNIIGHQFFWFLKAEMH--DNRVTE-------RYGVLLEAFLNGC-ED 708
Query: 1079 LNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYV 1138
L + L +A VK + + +LPL +
Sbjct: 709 YRTELYNEVTFQNQLVVIANKVKQLE--TKEEQKQLLKDSLAKLKYPEEMSLPLDSRFRI 766
Query: 1139 HDLDVKSCTYFSSNTLPLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVIKIMDTLWL 1196
+ FSS PL + D I + KVGDDLRQD L LQ++++M+ +W
Sbjct: 767 KKPIPNTGNVFSSKKKPLMLVLENVDPLGDNIMVIQKVGDDLRQDVLTLQMLQLMNNIWK 826
Query: 1197 KAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSF---KDKPIAEWLAKH 1253
AGLDLRM+ + T N GM+E+V ++ET I + G G+ K+ + +WL K
Sbjct: 827 SAGLDLRMLPYHCTATGNEIGMLELVQDSETYGKIIADEGGQGTLRVCKEDLLTKWLKKQ 886
Query: 1254 ---NPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGD 1310
S++ +++A +NFT SCAGY VATY+LG+ DRH+DN+M++ G FHIDFG FLG
Sbjct: 887 CSRKESKVTFEQAVENFTYSCAGYCVATYILGVGDRHSDNVMIRRDGRFFHIDFGHFLGH 946
Query: 1311 AQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHIL 1370
+ KR +R PF T +V+ GG+ TQ F F +LC AF +R +
Sbjct: 947 FKSKFGVKR----ERTPFKFTQHFAHVM-GGKGSTQ-FGIFEDLCLRAFACIRKQGSLFI 1000
Query: 1371 DLFAL 1375
LF L
Sbjct: 1001 YLFRL 1005
Score = 36.3 bits (80), Expect = 6.4
Identities = 32/116 (27%), Positives = 60/116 (51%), Gaps = 14/116 (12%)
Query: 381 KFVYTD-ERTNPGHVIAARSGGKYPPNTSIKILVHHAHSDEPITFTSDVESKVEHVILTV 439
++VY + E P I + G+Y + S+K +V +P +D +KV + + T
Sbjct: 189 EYVYVESEPPIPTSCIELKINGRYGVDMSMKTIVQ-----KP----TDTIAKVINNLFTK 239
Query: 440 VCSLDEDI---REDMSGYMLRVRGAKEYLTPGSS-LSEYDYIRECVRLEKDVTLCL 491
+ ++ I S ++L+VRG+ + LS++DYIR+CVRL +++ + L
Sbjct: 240 LYTMKPKIFDKNSKPSDFVLKVRGSNDNNDKIEYILSDFDYIRKCVRLNQNIDVVL 295
>UniRef50_A0DLV0 Cluster: Chromosome undetermined scaffold_556, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_556, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1225
Score = 190 bits (464), Expect = 2e-46
Identities = 99/209 (47%), Positives = 130/209 (62%), Gaps = 8/209 (3%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK GDD+RQD L LQ+IKIMD +WL GLD RM ++ + T + GMIE+V ++T +
Sbjct: 961 IFKCGDDIRQDLLTLQLIKIMDKIWLDFGLDYRMKPYKVISTLDQVGMIEVVLNSDTTSS 1020
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
I G G+ I E+L KHN +E A +NF SCAGY VATYLLGI DRH+ N
Sbjct: 1021 IHENAGKFGALNKSSIMEYLKKHNKHSME--NAVENFLRSCAGYCVATYLLGIGDRHSGN 1078
Query: 1291 IMLKTSGHLFHIDFGKFLGD--AQMFGNFKRLVYI--DRAPFVLTHDMVYVINGGERPTQ 1346
IML SGHLFHIDFG FLG+ + GNFK I +R PFV T +M YV+ G +
Sbjct: 1079 IMLTESGHLFHIDFGHFLGNKLTIILGNFKTKYGINRERTPFVFTQEMAYVMGGVQ--GH 1136
Query: 1347 RFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
FQ F + C A+N +R H ++++F +
Sbjct: 1137 NFQRFEDFCTKAYNQIRQHGHLLINIFLM 1165
Score = 37.5 bits (83), Expect = 2.8
Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 900 ECREVMWEKRQYLVQIPGALPLVLLAATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLP 958
E + ++ + R + P A P+ L A NW + ++ ++++W +A+ LL
Sbjct: 678 EDKFILLKCRNHYKNQPSAFPI-FLCAINWSDPEEIREVYQMMKVWTSLPSDDALPLLDA 736
Query: 959 CFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
D VR A K + DD+L + +LTQAL E
Sbjct: 737 NISDELVRYYATKRVGLYKDDELVLFMLELTQALIFE 773
>UniRef50_UPI0000F21165 Cluster: PREDICTED: hypothetical protein; n=2;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1069
Score = 188 bits (457), Expect = 1e-45
Identities = 113/323 (34%), Positives = 174/323 (53%), Gaps = 14/323 (4%)
Query: 1063 RYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCA-KEXXXXXXXXXXXXXXXX 1121
R ++L A L+ CGE + Q +V L ++A++VK +
Sbjct: 689 RMAVILEAYLLGCGEAMLAEFQSQVQVVSYLHDVALAVKLLYPDRTDLPSTAPQKLQELL 748
Query: 1122 XXXXQPTALPLALHKYVH--DLDVKSCTYFSSNTLPLKINFIGTDNAVIPA-----MFKV 1174
P+ + V + +K C +S PL + F + P+ +FK
Sbjct: 749 EKCDLPSDFQVPFDPRVRAGSIILKDCKIMASKKKPLWLEFSCIQSEAPPSPPVGIIFKH 808
Query: 1175 GDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ-T 1233
GDDLRQD L++Q + +MD++W + GLDL +V + + T + GMIEIV A T+ ++Q +
Sbjct: 809 GDDLRQDMLIIQTLVVMDSIWQEKGLDLNLVPYGCISTGFNIGMIEIVRNAITIASVQRS 868
Query: 1234 EWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML 1293
+ G+ G+FK+ + +WL P + ++ +A + F SCAGY VATY+LGI DRHNDNIM+
Sbjct: 869 QGGVAGAFKNNALYDWLQTKCPFQEKHFQATEKFVNSCAGYCVATYVLGIGDRHNDNIMI 928
Query: 1294 KTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGE-RPTQRFQHFV 1352
G+LFHIDFG LG+ + F R +R PFVLT D +YV+ + RP+ FQ F
Sbjct: 929 TDQGNLFHIDFGHILGNTKSFWGVNR----ERVPFVLTPDFLYVMGRVKGRPSLYFQRFR 984
Query: 1353 ELCCMAFNIVRAHHDHILDLFAL 1375
+ C A+ +RA ++ LF+L
Sbjct: 985 DTCINAYLSLRAQSRLLVTLFSL 1007
>UniRef50_UPI0000EBCA32 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Bos taurus|Rep: PREDICTED: hypothetical
protein, partial - Bos taurus
Length = 476
Score = 186 bits (454), Expect = 3e-45
Identities = 97/231 (41%), Positives = 136/231 (58%), Gaps = 16/231 (6%)
Query: 1145 SCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRM 1204
+C+YF+SN LPLKI FI + P + + ++ +I + ++L+
Sbjct: 1 ACSYFTSNALPLKITFINAN----PMGKNISVIFKNNSTCPTMIGNKSNITGSKPMNLQC 56
Query: 1205 VTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRAR 1264
T G++++V +A TL I +G G K+ I +W ++HNP + +Y++
Sbjct: 57 KT--------PGGLVQMVPDAVTLAKIHRCFGPIGPLKENTIKKWFSQHNPLKADYEKVL 108
Query: 1265 DNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYID 1324
NF SCAG+ V T++LG+CDRHNDNIML SGH+FHIDFGKFLG AQ FG KR D
Sbjct: 109 RNFFYSCAGWCVVTFILGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKR----D 164
Query: 1325 RAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
RAPF+ T +M Y I G + Q FQ FVELCC A+NIVR H +L+L +
Sbjct: 165 RAPFIFTSEMEYFITEGGKNPQHFQDFVELCCRAYNIVRRHSRLLLNLLEM 215
>UniRef50_Q4RYW3 Cluster: Chromosome 16 SCAF14974, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 16
SCAF14974, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1008
Score = 186 bits (453), Expect = 4e-45
Identities = 101/251 (40%), Positives = 151/251 (60%), Gaps = 11/251 (4%)
Query: 1131 PLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVI 1188
PL + + ++V+ C Y S PL I + ++ +FK GDDLRQD L LQ++
Sbjct: 699 PLNPNILLSGINVEKCRYMDSKMKPLWIVYNNKLLLGDMLGIIFKNGDDLRQDMLTLQIL 758
Query: 1189 KIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ---TEWGLTGSFKDKP 1245
++MDTLW +A LDLR+V + L T + G+IE+V+ A+T+ IQ + +F
Sbjct: 759 RLMDTLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNMAAAAAFNKDA 818
Query: 1246 IAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFG 1305
+ WL + N + +RA + FT SCAGY VATY+LGI DRH+DNIM++++G LFHIDFG
Sbjct: 819 LLNWLKERNSGDA-LERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSNGQLFHIDFG 877
Query: 1306 KFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER-PTQRFQHFVELCCMAFNIVRA 1364
LG+ + KR +R PF+LTHD ++VI G+ ++F F + C A+ I+R
Sbjct: 878 HILGNFKSKFGIKR----ERVPFILTHDFIHVIQQGKTGQAEKFGSFRQYCEKAYLILRK 933
Query: 1365 HHDHILDLFAL 1375
+ + + LFAL
Sbjct: 934 NGNLFITLFAL 944
Score = 67.3 bits (157), Expect = 3e-09
Identities = 53/214 (24%), Positives = 93/214 (43%), Gaps = 8/214 (3%)
Query: 792 LGWAALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXX----XXXXXXXXXXXXVVNIEIPL 847
+ W +FD+ G L +G+ +L W + D ++I P
Sbjct: 370 IAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPIGTVQTNPYTENATALHISFPE 429
Query: 848 YAHTGVKWTSGEED--KQKNISLKDLPSFDSLDGHT-QSQLLHLIEQGAYQRMPTECREV 904
++ + + ++ N F G +L ++E+ A ++ +++
Sbjct: 430 FSSHPIIFPPFDKVIVVSPNQPFHSHHVFKGRGGKKFHIELKEIMERDALSQLCENEKDL 489
Query: 905 MWEKR-QYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDV 963
+W R P +LP +LL+ + QL LL++W + SP +A+ LL +PD
Sbjct: 490 IWTLRCDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPRLSPRDALELLDFNYPDQ 549
Query: 964 AVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
VRE A L +MS+D+L + L QL Q LR+E Y
Sbjct: 550 YVREYAVNCLRDMSNDELSQYLLQLVQVLRYEPY 583
>UniRef50_P42336 Cluster: Phosphatidylinositol-4,5-bisphosphate
3-kinase catalytic subunit alpha isoform; n=38; root|Rep:
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
subunit alpha isoform - Homo sapiens (Human)
Length = 1068
Score = 183 bits (446), Expect = 3e-44
Identities = 104/256 (40%), Positives = 149/256 (58%), Gaps = 16/256 (6%)
Query: 1131 PLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTD--NAVI----PAMFKVGDDLRQDALV 1184
PL + +L ++ C SS PL +N+ D + ++ +FK GDDLRQD L
Sbjct: 754 PLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLT 813
Query: 1185 LQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGS--FK 1242
LQ+I+IM+ +W GLDLRM+ + L + G+IE+V + T+ IQ + GL G+ F
Sbjct: 814 LQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFN 873
Query: 1243 DKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHI 1302
+ +WL N E+ Y A D FT SCAGY VAT++LGI DRHN NIM+K G LFHI
Sbjct: 874 SHTLHQWLKDKNKGEI-YDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHI 932
Query: 1303 DFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER---PTQRFQHFVELCCMAF 1359
DFG FL + +KR +R PFVLT D + VI+ G + T+ F+ F E+C A+
Sbjct: 933 DFGHFLDHKKKKFGYKR----ERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAY 988
Query: 1360 NIVRAHHDHILDLFAL 1375
+R H + ++LF++
Sbjct: 989 LAIRQHANLFINLFSM 1004
Score = 62.9 bits (146), Expect = 6e-08
Identities = 80/321 (24%), Positives = 127/321 (39%), Gaps = 45/321 (14%)
Query: 694 DEYMFHAQIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVL 753
D+ IYHG PL TQ ++ C PR ++ WLN D+ + LPR +RL L
Sbjct: 352 DKIYVRTGIYHGGEPLCDNVNTQ--RVPCSN--PR--WNEWLNY-DIYIPDLPRAARLCL 404
Query: 754 TLHGRTQRTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVL 813
++ S + A++ E L W + LFD+ L SG L
Sbjct: 405 SIC---------------SVKGRKGAKE------EHCPLAWGNINLFDYTDTLVSGKMAL 443
Query: 814 PLW--PTSCDRRXXXXXXXXXXXXXXXXVVNIEIPLYAHT-----------GVKWTSGEE 860
LW P + + +E ++ W+ E
Sbjct: 444 NLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSRE 503
Query: 861 D--KQKNISLKDLPSFDS-LDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPG 917
+ L + + D+ L + + QL + + + + ++ +W R Y V IP
Sbjct: 504 AGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPE 563
Query: 918 ALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNE-M 976
LP +LL+ D Q+ L++ W P AM LL +PD VR A + L + +
Sbjct: 564 ILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYL 623
Query: 977 SDDDLCRVLPQLTQALRHETY 997
+DD L + L QL Q L++E Y
Sbjct: 624 TDDKLSQYLIQLVQVLKYEQY 644
>UniRef50_UPI0000499EE5 Cluster: phosphatidylinositol 3-kinase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: phosphatidylinositol
3-kinase - Entamoeba histolytica HM-1:IMSS
Length = 1124
Score = 175 bits (427), Expect = 6e-42
Identities = 184/650 (28%), Positives = 278/650 (42%), Gaps = 71/650 (10%)
Query: 739 DLPVNTLPRESRLVLTLHGRTQR---TIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWA 795
DLP+ LP+E++LV+ + ++ TID E + ++ +G
Sbjct: 472 DLPIKILPKETKLVIGVFQTEEQIGVTIDHLEKKEKN---------------KENPIGTI 516
Query: 796 ALQLFDFDGMLSSGNYVLPLWPTSCDRRXXXXXXXXXXXXXXXXVVNIEIPLYAHTGVKW 855
++ D +GML GN LW S + P Y V
Sbjct: 517 NCKVVDHNGMLLMGNVQCGLWELSAPN---FISMCSENIGERAIYLTFTYPTY-DVPVLM 572
Query: 856 TSGEEDKQKNISLKDLPSFDSLDGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQI 915
+ +D K+ D + L + +E Q++ + +++W+ R + +
Sbjct: 573 DAFNDDNIKS----DNQEKEKLTAEQTKKFKVALESNPLQKLTEDEMKLIWKLRYTVKKT 628
Query: 916 PGALPLVLLAATNWYGDHR-EQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLN 974
++AA + H +L LL W P A+ +L FPD VR+ A K L+
Sbjct: 629 KPKNLSRVVAAVDLTDVHAVAELHRLLADWPLLEPQTAIEMLDFKFPDQRVRDFALKCLD 688
Query: 975 EMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQA 1034
M D +L LPQL QAL+ E + +LL +L N +
Sbjct: 689 AMDDAELIMFLPQLIQALKFELHHNSELA-----------------MFLLRRALRNKNRI 731
Query: 1035 PHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLC 1094
HQ F + E +N T+ RY L+L A + CG+ L + L
Sbjct: 732 GHQFFWFLKAE--LHDNRVTE-------RYGLLLEAFVGACGK-YQIELYNEVKFQLDLI 781
Query: 1095 EMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTL 1154
++A VK Q ALP+ S FSS
Sbjct: 782 DIANHVKTLATKDEQKQYMFEALAKLKYPDNQ--ALPIDSRMRFTKPVPNSGNVFSSKKK 839
Query: 1155 PLKINFIGTDNAV--IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPT 1212
PL + D A I + KVGDDLRQD L LQ+++IM T+ A LD+RM+ +Q + T
Sbjct: 840 PLLLILQNYDPAGDDIRVIEKVGDDLRQDILTLQILRIMFTMLKNAELDIRMLPYQCIAT 899
Query: 1213 SNSKGMIEIVTEAETLRAIQTEWGLTGSF-KDKPIAEWLAKH--NP-SELEYQRARDNFT 1268
N GM+E+V ++ET I + G + K+ + W+ K P S++ +++A +NF
Sbjct: 900 GNETGMLELVKDSETYGKIIADDGRRLAVTKNDVLTLWMQKQCARPESKVTFEQAVENFV 959
Query: 1269 ASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPF 1328
SCAGY VATYLLGI DRH+DN+M+ G FHIDFG FLG+ + KR +R PF
Sbjct: 960 HSCAGYCVATYLLGIGDRHSDNVMVTRDGIFFHIDFGHFLGNFKSKFGVKR----ERTPF 1015
Query: 1329 VLTH---DMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
T D++ +G E ++ F+ F ELC A +R + LF L
Sbjct: 1016 KFTQHYADLMGYKDGVE--SKEFKEFKELCSSALLSLRKQGSLFIYLFRL 1063
>UniRef50_UPI00004983C1 Cluster: phosphatidylinositol-4,5-bisphosphate
3-kinase; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
phosphatidylinositol-4,5-bisphosphate 3-kinase -
Entamoeba histolytica HM-1:IMSS
Length = 1044
Score = 173 bits (420), Expect = 4e-41
Identities = 96/285 (33%), Positives = 149/285 (52%), Gaps = 16/285 (5%)
Query: 1094 CEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHK-YVHDLDVKSCTYFSSN 1152
CE A++V+ A+P+ + L + ++SN
Sbjct: 706 CEFALNVQTVNSTLIRMDSEKRQIYRSALLKSISVAVPIPFKPGVIGGLSCEKSKVYTSN 765
Query: 1153 TLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPT 1212
+PL I+F G +FK+GDDLRQD L+L+ K+ D LW G+D RM TF+ + T
Sbjct: 766 AVPLLIDFSG-----YKMIFKLGDDLRQDCLILRAFKLFDNLWRMNGMDWRMTTFRVIST 820
Query: 1213 SNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCA 1272
N+ G IE V ++ ++ +I + + G +K I +W+ + + L + +NF SC
Sbjct: 821 GNTAGYIEFVRDSRSIGSIHNDSKIPGVYKVTAIYDWIKNNKTAPL--GQCIENFYRSCV 878
Query: 1273 GYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTH 1332
GY VA+Y+LG+ DRHNDN+M+ SGH HIDF FLG+ ++ + APFVLT
Sbjct: 879 GYCVASYVLGLADRHNDNLMVDKSGHFLHIDFAHFLGNKLKVAG---VINREPAPFVLTE 935
Query: 1333 DMVYVINGGERPTQR----FQHFVELCCMAFNIVRAHHDHILDLF 1373
M+YV GER T+R ++ F E C A++++R + I+ F
Sbjct: 936 SMIYVF-AGERGTERYKLKYREFCEDCVRAYHVLRQNASLIVSFF 979
>UniRef50_A2DYA6 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Trichomonas vaginalis G3|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Trichomonas vaginalis G3
Length = 1142
Score = 168 bits (409), Expect = 9e-40
Identities = 95/249 (38%), Positives = 137/249 (55%), Gaps = 9/249 (3%)
Query: 1130 LPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGT---DNAVIPAMFKVGDDLRQDALVLQ 1186
LP+ V ++ C +S P + F I MFKVGDDLRQD L LQ
Sbjct: 840 LPVDPRLVVDRFIIEECKVMNSKKKPFWLTFHNAAPFSTEPIQTMFKVGDDLRQDHLTLQ 899
Query: 1187 VIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPI 1246
V+K+MD +W + LDLRM + LPT ++G IE+V + T + +Q E G GSF +
Sbjct: 900 VMKVMDYIWRQNNLDLRMSNYSVLPTGLNQGFIEVVPNSVTEQKLQQEKGKMGSFDENTF 959
Query: 1247 AEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGK 1306
++L N +E Q A++NF S AGY+VAT +LG+ DRH NIML+ GH FHIDFG
Sbjct: 960 IDYLKLMNTTEQTLQMAKENFMLSSAGYAVATCILGVADRHPGNIMLQQDGHFFHIDFGH 1019
Query: 1307 FLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHH 1366
FLG+ + +KR + APF V V++G + + ++ F + A+N++R
Sbjct: 1020 FLGNFKKKLGYKR----ENAPFHFLPACVVVLDG--QNGKLYKEFEQTSIKAYNVMREKA 1073
Query: 1367 DHILDLFAL 1375
+ I+ L L
Sbjct: 1074 NLIMSLMLL 1082
Score = 59.7 bits (138), Expect = 6e-07
Identities = 36/116 (31%), Positives = 58/116 (50%)
Query: 882 QSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLL 941
Q +L L + + R+++W R V P LPLVL + ++ +L
Sbjct: 622 QFRLKELEAYDPLMELTDDDRKLIWLNRNRFVDNPKMLPLVLQSVDYTNTTQINEIPYVL 681
Query: 942 RLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
+W+ P A+ LL F D VR+ A LL++++D +L + QLTQAL++E Y
Sbjct: 682 AMWKPLDPTGALTLLDAKFADENVRKYAVDLLDQLNDSELLLYILQLTQALKYEVY 737
>UniRef50_A4RAX1 Cluster: Putative uncharacterized protein; n=3;
Pezizomycotina|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 927
Score = 167 bits (407), Expect = 2e-39
Identities = 134/507 (26%), Positives = 220/507 (43%), Gaps = 28/507 (5%)
Query: 881 TQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGL 940
T+ +L +++ + + R+++W+ R +L + AL + + + Q + +
Sbjct: 372 TRDELNNILSYSPTHPLTPDERDLVWKFRYHLSRDKRALTKFVKSVSWQDQSESRQAVQV 431
Query: 941 LRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXX 1000
L W + +A+ LL P F AVR A L + D +L L QL QAL+ E
Sbjct: 432 LAKWTEIDVDDALELLGPTFEYPAVRAYAVDRLRKADDGELLLYLLQLVQALKFEHIPTI 491
Query: 1001 XXXXXXXXXXXXXXXXXXXXF--WLLVHSLPNIPQAPH-QEFLGINLEDNASENAETDAS 1057
+L+ + N + +L + +D + + +
Sbjct: 492 DRGHREAAEAGGVAAAQDSSLARFLIARASQNFMLGNYFYWYLMVECDDLSQDQLPEYRT 551
Query: 1058 MSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXX 1117
+ Y M + G + KTLLRQ + L +++ +K A E
Sbjct: 552 IYRKVAYDFMTELVARPGGADTRKTLLRQAEWIAILSKISAEIKEANESIARRTDRVKHL 611
Query: 1118 XXX----XXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFK 1173
P LPL + + + T F S+ P+K+ F P +FK
Sbjct: 612 LADPKNELITINPPLPLPLDPSQKIVGVVPDESTVFKSSLHPIKVTFKTDTGQKYPILFK 671
Query: 1174 VGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQT 1233
GDDLRQD LV+Q+I +MD L K LDL++ ++ L TS S G+ + V +++ + I
Sbjct: 672 TGDDLRQDQLVVQIITLMDQLLQKENLDLKLSPYKILATSTSAGLTQFVA-SQSFQTIAN 730
Query: 1234 EWGLTGSFKDKPIAEWLAKHNPSELE----YQRARDNFTASCAGYSVATYLLGICDRHND 1289
+ + P +L HNP + + A D F SCAGY V TY+LG+ DRH D
Sbjct: 731 RFSRSNV---PPALAYLRHHNPDDAAPLGVRKEAHDMFVRSCAGYCVITYILGVGDRHLD 787
Query: 1290 NIMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
N++L GH FH DFG LG D + F + L+ +MV + G + +
Sbjct: 788 NLLLAPDGHFFHADFGFILGRDPKPFAPAMK----------LSREMVDAMGGA--GSDGY 835
Query: 1349 QHFVELCCMAFNIVRAHHDHILDLFAL 1375
+ F + C +AF+ +R + IL+LF+L
Sbjct: 836 RAFKQYCFLAFSALRKSSNLILNLFSL 862
>UniRef50_A2DJM8 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=4; Trichomonas vaginalis G3|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Trichomonas vaginalis G3
Length = 1134
Score = 164 bits (398), Expect = 2e-38
Identities = 98/245 (40%), Positives = 138/245 (56%), Gaps = 11/245 (4%)
Query: 1130 LPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGT---DNAVIPAMFKVGDDLRQDALVLQ 1186
LP+ V V+ C +S P + F I +FKVGDDLRQD L LQ
Sbjct: 830 LPMDPRLVVDAFIVEKCKVMNSKKKPFWLTFHNAAPFSTEPIRVLFKVGDDLRQDQLTLQ 889
Query: 1187 VIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWG-LTGSFKDKP 1245
V+++M+ LW K G+DL M + LPT ++G IE+V A T +A+Q E G G + +
Sbjct: 890 VMRVMEYLWRKEGIDLHMRCYGVLPTGFNQGFIEVVPNAITEQALQQEKGTFAGVWDNNT 949
Query: 1246 IAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFG 1305
+ ++L K N +E Q AR+NF S AGY+VAT +LGI DRH NIML+T GH HIDFG
Sbjct: 950 LTDYLYKVNTTEQNQQLARENFMYSSAGYAVATCVLGIADRHPGNIMLQTDGHFLHIDFG 1009
Query: 1306 KFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAH 1365
FLG+ + ++R + APF + V+ G+ + F+ F +LC A NI+R H
Sbjct: 1010 HFLGNFKTKLGYQR----ENAPFHFSPACANVL--GDVNGEMFKQFRKLCGDALNILR-H 1062
Query: 1366 HDHIL 1370
+ +L
Sbjct: 1063 NSKLL 1067
Score = 65.3 bits (152), Expect = 1e-08
Identities = 35/103 (33%), Positives = 55/103 (53%)
Query: 895 QRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMH 954
+++ E + +++ R L + LPLVL + ++ GLL+ WEKP P A+
Sbjct: 625 KKLTMEEKNLIYRYRHDLYDMSSFLPLVLSSIDYTVPTQAHEIAGLLQQWEKPKPAEALS 684
Query: 955 LLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
LL F D VR A + L +SDD++ + QL QAL++E Y
Sbjct: 685 LLDSEFADQRVRAYAVECLESLSDDEIMLYMLQLVQALKYEMY 727
>UniRef50_A6S8M7 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 973
Score = 163 bits (397), Expect = 3e-38
Identities = 136/506 (26%), Positives = 217/506 (42%), Gaps = 41/506 (8%)
Query: 882 QSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHR-EQLIGL 940
+ +L ++I + E ++++W+ R +L + AL + + NW + + + +
Sbjct: 433 RDELNNIIAYSPTHFLSPEEKDLVWKFRHHLARDKRALTK-FIKSVNWNDPNEAREAVAM 491
Query: 941 LRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXX 1000
L W + +A+ LL P F + +VR A L + DD+L L QL QAL+ E
Sbjct: 492 LSKWTEIDVDDALELLGPTFENSSVRTYAVDRLRKSDDDELLLYLLQLVQALKFEHISPD 551
Query: 1001 XXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQAPH--QEFLGINLEDNASENAETDASM 1058
LL+ N Q + +L + +D + + +
Sbjct: 552 SAEDAAQDSSLAR---------LLISRATNNFQLGNLFHWYLMVECDDKSEDQGAGYRKL 602
Query: 1059 SASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXX 1118
A Y M + G K LLRQ L+ L ++ +K +++
Sbjct: 603 FAKVEYDFMTELVKNPEGVETRKVLLRQAELITMLSRVSEDIKSSRDTVSRKAEKVKQFL 662
Query: 1119 XX----XXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKV 1174
P LPL + +D F S+ P+ I F T +FK
Sbjct: 663 ADPKNELITIDPPLPLPLDPSIMITGVDPSETNVFKSSLFPIMITFKTTTKQKYQIIFKT 722
Query: 1175 GDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTE 1234
GDDLRQD LV+Q+I +MD L K LDL++ ++ L T + G ++ V + TL++I
Sbjct: 723 GDDLRQDQLVIQIITLMDQLLQKENLDLKLSPYKILATGATAGAVQFV-PSMTLQSI--- 778
Query: 1235 WGLTGSFKDKPIAEWLAKHNPSELE----YQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
FK + +L +NP + + A D F SCAGY V TYLLG+ DRH DN
Sbjct: 779 ---VNKFKGNTVLNYLKSNNPDDKASLGVRKEALDVFIKSCAGYCVITYLLGVGDRHLDN 835
Query: 1291 IMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQ 1349
++L GH FH DFG LG D + F + L +MV + G ++ +
Sbjct: 836 LLLAPDGHFFHADFGFILGRDPKPFAPAMK----------LCKEMVDGMGGS--MSEHYP 883
Query: 1350 HFVELCCMAFNIVRAHHDHILDLFAL 1375
F + C A+ +R + IL+LF+L
Sbjct: 884 QFKQYCFTAYTTLRKSSNLILNLFSL 909
>UniRef50_Q2U4A1 Cluster: Phosphatidylinositol 3-kinase VPS34; n=14;
Pezizomycotina|Rep: Phosphatidylinositol 3-kinase VPS34 -
Aspergillus oryzae
Length = 902
Score = 160 bits (388), Expect = 3e-37
Identities = 139/492 (28%), Positives = 214/492 (43%), Gaps = 43/492 (8%)
Query: 895 QRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWY-GDHREQLIGLLRLWEKPSPLNAM 953
Q + E ++++W R YL + AL + + NW Q + +L W + +A+
Sbjct: 378 QDLTAEEKDLVWRFRYYLTREKRALTK-FVKSVNWRDAGESHQAVEILPKWTEIDVDDAL 436
Query: 954 HLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXX 1013
LL P F + AVR A + L + D++L L QL QAL++E
Sbjct: 437 ELLGPTFDNPAVRSYAVERLRKADDEELLLYLLQLVQALKYEDNSNVDTEDAAHDSSLAN 496
Query: 1014 XXXXXXXFWLLVHSLPNIPQAPHQE-FLGINLEDNASENAETDASMSASWRYTLMLRALL 1072
+L+ + N + +L + +D + + A Y M A L
Sbjct: 497 --------FLITRAANNFKLGSYFHWYLMVECDDTSPGTLSAQRRLFARVEYYFM--ADL 546
Query: 1073 VICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXX----XXXXXQPT 1128
KTLLRQ LV L ++A ++ +++ P
Sbjct: 547 EQVHPEHRKTLLRQGELVAVLSKIAKDLRFSRDNRLLKIEKLKKYLKDPKNELVHIDPPL 606
Query: 1129 ALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVI 1188
LP+ V + F S PL I F ++ P +FKVGDDLRQD LV+Q+I
Sbjct: 607 PLPIDPEISVTGCFPDNSNVFKSTLSPLLITFKTSEGQKYPILFKVGDDLRQDQLVIQII 666
Query: 1189 KIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAE 1248
+MD L K LDL++ ++ L T+ + G ++ + A +L AI S K + +
Sbjct: 667 ILMDRLLQKENLDLKLTPYRILATNATAGAVQFIPSA-SLSAI--------SAKHRSVLA 717
Query: 1249 WLAKHNPSELE----YQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDF 1304
+L +NP E E + D + SCAGY V TYLLG+ DRH +N++L GH FH DF
Sbjct: 718 YLQANNPDESEPLGVRKETMDTYIKSCAGYCVITYLLGVGDRHLENLLLAPDGHFFHADF 777
Query: 1305 GKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVR 1363
G LG D + F + L +MV + G P + F + C A+ +R
Sbjct: 778 GFILGRDPKPFAPMMK----------LCKEMVEGMGGTTSP--HYLQFKQYCFTAYTTLR 825
Query: 1364 AHHDHILDLFAL 1375
+ IL+LF+L
Sbjct: 826 KSANLILNLFSL 837
>UniRef50_Q54F55 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1820
Score = 159 bits (385), Expect = 7e-37
Identities = 137/488 (28%), Positives = 207/488 (42%), Gaps = 43/488 (8%)
Query: 902 REVMWEKRQYL-VQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCF 960
R ++WE R+Y + P LP +L + R +L LL+ W SP + LL F
Sbjct: 1306 RSILWENREYCKINYPNILPTLLYNYSILSWSSRVELYRLLKDWPMISPSFGLELLSSDF 1365
Query: 961 PDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE-TYXXXXXXXXXXXXXXXXXXXXXX 1019
D +RE + +N+ D+ L LPQ+ L++E T
Sbjct: 1366 IDDRIREIGVQSINQWPDNQLSLYLPQIVSMLKYEPTNYSALVNFIVKRSICNPIKIGQP 1425
Query: 1020 XFWLLVHSLPNIPQAPH------------QEFLGINLEDNASENAETDASMSASWRYTLM 1067
FWL + + + H E LGI + ++ + + +
Sbjct: 1426 VFWLCSNEISPLENKNHIIIRYKLVMEIILEGLGIGVINSTTTTTNNEQQQQQQQQQQQQ 1485
Query: 1068 LRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQP 1127
+ + ++L+ Q LL++ L E+ + + KE P
Sbjct: 1486 QQQQQQNSNK-FGQSLVSQYLLLRLLKEINIDI--IKEPEKQKQIFETRLSLLPKVFTLP 1542
Query: 1128 TALPLALHKYV-HDLDVKSCTYFSSNTLPLKINFIGTDNAV--IPAMFKVGDDLRQDALV 1184
T + +V +L VK SN PL + F D +FK DD+R D L
Sbjct: 1543 THPYQEFNSFVLEELKVKD-----SNAAPLWLVFSSIDKEADDTKIIFKK-DDVRPDELC 1596
Query: 1185 LQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDK 1244
LQ+ +MD++ GLD F+ L + G+IE+V ++ TL + + K
Sbjct: 1597 LQLFSLMDSILKSNGLDCEFTIFKCLSAKSGLGLIEVVPDSVTLADFMRD-----TTKYP 1651
Query: 1245 PIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDF 1304
I +WL NP D F SC+ Y VATYLLGI DRHNDN+M+ +GH HIDF
Sbjct: 1652 SIEQWLKLKNPPNSTQHI--DIFIKSCSVYCVATYLLGIYDRHNDNLMVSATGHFLHIDF 1709
Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRA 1364
G FLG F F+R + APFVLT D+V ++ E + F L C +NI+R
Sbjct: 1710 GYFLGKVTKFLMFER----ETAPFVLTKDIVAMLGSRE------EEFKVLSCKIYNILRD 1759
Query: 1365 HHDHILDL 1372
+ +L+L
Sbjct: 1760 NSRQLLNL 1767
>UniRef50_A4RU70 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 654
Score = 154 bits (373), Expect = 2e-35
Identities = 140/508 (27%), Positives = 213/508 (41%), Gaps = 55/508 (10%)
Query: 878 DGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQL 937
DG + +L +I+ + + E + ++W+ R + P AL L +W Q
Sbjct: 126 DGAEKRRLSAIIQLPPTRPLDMESQNLLWKFRFAISHDPRALTK-FLKCVDWSDPAETQA 184
Query: 938 -IGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHET 996
+ L+R W P A+ LL P F + VR A +L + ++DL L QL QALR+ET
Sbjct: 185 SVQLMREWAPIGPAAALELLTPTFSNSEVRRYAVSILRQAENEDLLLYLLQLVQALRYET 244
Query: 997 YXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDA 1056
+W ++ + P + + + AS +T
Sbjct: 245 ADDNELAKFLVERAVANEVVGNYLYWYVL--VQRTPPPAERSMSAFRMFERASRAKDTRG 302
Query: 1057 SMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXX 1116
+ W R L+ E + T++ Q++ +++ A++
Sbjct: 303 R--SVWETLKFQRELM----EKI--TIITQEVN---------TLRGARKVERLRAILSSD 345
Query: 1117 XXXXXXXXXQPTALPLALHKYVHDLDV--KSCTYFSSNTLPLKINFIGTDNAVIPAMFKV 1174
P A+P L+ V + F S PLK+ F +FK
Sbjct: 346 NTLGAVLTSFPQAIPNPLNPTVLTTGILASESNVFKSALSPLKLAFQTLTGDSATMIFKK 405
Query: 1175 GDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTE 1234
GDDLRQD L +Q+I +MD L + LDL++ +++ L T N G+IE V
Sbjct: 406 GDDLRQDQLCVQMISLMDKLLKRENLDLKLTSYRVLATGNDTGLIEFVKSQ--------- 456
Query: 1235 WGLTGSFKD-KPIAEWLAKHNPSELE----YQRARDNFTASCAGYSVATYLLGICDRHND 1289
GL K+ + + ++A HNP + NF SCAGYSV TYLLG+ DRH D
Sbjct: 457 -GLADILKEHEKLTTYIALHNPDPHGPNGCTMTSMMNFVKSCAGYSVITYLLGVGDRHLD 515
Query: 1290 NIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQ 1349
N+ML + G LFHIDFG +G R I L +MV E + F
Sbjct: 516 NLMLASDGRLFHIDFGFIMG---------RDPKISPPSMKLCKEMV------EAMGEYFS 560
Query: 1350 HFVELCCMAFNIVRAHHDHI--LDLFAL 1375
F CC A+NI+R + L+LF+L
Sbjct: 561 EFKTYCCEAYNILRKSESVVLLLNLFSL 588
>UniRef50_A2DM61 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Trichomonas vaginalis G3|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Trichomonas vaginalis G3
Length = 1156
Score = 152 bits (368), Expect = 8e-35
Identities = 89/252 (35%), Positives = 140/252 (55%), Gaps = 14/252 (5%)
Query: 1130 LPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGT---DNAVIPAMFKVGDDLRQDALVLQ 1186
LP+ V ++ C +S P + F + MFKVGDDLRQD L LQ
Sbjct: 853 LPMDPRLVVDAFILEDCKVMNSKKKPFWLTFHNAAPFSTEPVKTMFKVGDDLRQDQLTLQ 912
Query: 1187 VIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGL-TGSFKDKP 1245
++K+M+ LW + LDLRM + LPT ++G IE+V + T + +Q E G TG FK
Sbjct: 913 IMKVMEHLWRQNQLDLRMNCYGVLPTGFNQGFIEVVPNSITEQVLQQEEGRWTGVFKPNI 972
Query: 1246 IAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFG 1305
+ ++LAK+N + + A++NF S AGY+V++ ++G+ DRH NIM++ GH FHIDFG
Sbjct: 973 MNDFLAKNNSTAVTLNIAKENFLLSSAGYAVSSCVIGLADRHPGNIMVQRDGHFFHIDFG 1032
Query: 1306 KFLGDAQMFGNFKRLVYIDR--APFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVR 1363
FL GNFK+ + R APF + + G +++++ F + A+NI+R
Sbjct: 1033 HFL------GNFKKKLGYQREDAPFHFSPACAEALGG--VGSEQYKRFEDTSANAYNILR 1084
Query: 1364 AHHDHILDLFAL 1375
+ + ++ + L
Sbjct: 1085 RNANLLMSMMLL 1096
Score = 48.8 bits (111), Expect = 0.001
Identities = 31/98 (31%), Positives = 49/98 (50%)
Query: 900 ECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPC 959
E + ++W R Q LPLVL + ++ +L W + SP +A+ LL P
Sbjct: 653 EDKTLIWNNRAKFKQNERMLPLVLQSLDYTSPVQVAEIPYILNEWAEISPTDALTLLDPK 712
Query: 960 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
F D VR+ A + L +D+++ + QL QAL+ E Y
Sbjct: 713 FADRDVRKYAVEHLEAFNDNEIMLYMLQLVQALKFELY 750
>UniRef50_P54676 Cluster: Phosphatidylinositol 3-kinase VPS34-like;
n=2; Dictyostelium discoideum|Rep: Phosphatidylinositol
3-kinase VPS34-like - Dictyostelium discoideum (Slime
mold)
Length = 816
Score = 140 bits (340), Expect = 2e-31
Identities = 90/254 (35%), Positives = 134/254 (52%), Gaps = 22/254 (8%)
Query: 1126 QPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVL 1185
QP LP+ + + + + S PL + T +FK DDLRQD L++
Sbjct: 516 QPIRLPVNPDIEIIGIVPEKSNIYKSAKSPLGLKLRTTKGEEYGVIFKTNDDLRQDQLII 575
Query: 1186 QVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKP 1245
Q+I +MD L K LDL++ ++ L T+ G++E+V +E + ++ +++ D
Sbjct: 576 QLISLMDRLLKKENLDLKLTPYKVLATAEEDGIVEMVNPSEAMASVLSKY-------DGD 628
Query: 1246 IAEWLAKHNP-SELEYQRA---RDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFH 1301
I ++ HNP ++ Y A D F SCAGY V TY+LGI DRH DN++L +G LFH
Sbjct: 629 ILKFFKTHNPDADSPYGIAPEVMDTFVKSCAGYCVITYILGIGDRHLDNLLLTPNGKLFH 688
Query: 1302 IDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNI 1361
IDFG LG I P L +MV + GGE ++ ++ F +LCC A+NI
Sbjct: 689 IDFGYILGKDPK---------ILPPPMKLCKEMVLGM-GGEN-SKHYEKFKQLCCEAYNI 737
Query: 1362 VRAHHDHILDLFAL 1375
+R IL+LFAL
Sbjct: 738 LRKSSHLILNLFAL 751
>UniRef50_Q5BXA1 Cluster: SJCHGC06189 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06189 protein - Schistosoma
japonicum (Blood fluke)
Length = 864
Score = 139 bits (336), Expect = 6e-31
Identities = 113/356 (31%), Positives = 162/356 (45%), Gaps = 48/356 (13%)
Query: 1063 RYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVK-CAKEXXXXXXXXXXXXXXXX 1121
R+ L+L A CG L RQ + L ++ VK A E
Sbjct: 453 RFGLILEAFCRGCGPML-ALFSRQVTALNRLEALSTRVKELASEEEQRELFYEEVSRPEA 511
Query: 1122 XXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAV------IPAMFKVG 1175
Q PL + + + +L + C S PL + + +D +FK G
Sbjct: 512 LHDLQWLPSPLCISETLGELLIHKCDVKRSKKKPLWLVWTNSDRLAQFHHKNYQMIFKHG 571
Query: 1176 DDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEW 1235
DDLRQD L LQ+ K+MD +W + G+D+ + ++ T G+IE V ++ T+ +IQ E
Sbjct: 572 DDLRQDMLTLQLFKLMDRIWKEEGMDMCLTSYGCFATGYEMGIIEAVRDSRTVMSIQGER 631
Query: 1236 GLTG-SFKDKPIAEWLAKH--------NPSELE----YQRARDNFTASCAGYSVATYLLG 1282
+ + +WL +H N S L Y+R FT SCAGY +AT++LG
Sbjct: 632 LRSALQIDSSQLYKWLMQHAKQKAKQLNHSTLSDNCAYERMIRTFTMSCAGYCIATFILG 691
Query: 1283 ICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI---- 1338
I DRH DNIM+ ++G LFHIDFG L + + F R +R PFVLT D V VI
Sbjct: 692 IRDRHPDNIMVDSTGRLFHIDFGHILDNRKKKFGFTR----ERVPFVLTRDFVTVIARGN 747
Query: 1339 -NGGERPTQ------------------RFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+GG T FQ F +LC A+ ++R H + IL L A+
Sbjct: 748 PDGGSLMTTNIPSSTVHATVGEINGNIHFQEFTDLCGKAYLLLRRHSNLILTLLAM 803
>UniRef50_P50520 Cluster: Phosphatidylinositol 3-kinase vps34; n=1;
Schizosaccharomyces pombe|Rep: Phosphatidylinositol
3-kinase vps34 - Schizosaccharomyces pombe (Fission
yeast)
Length = 801
Score = 139 bits (336), Expect = 6e-31
Identities = 136/505 (26%), Positives = 218/505 (43%), Gaps = 46/505 (9%)
Query: 882 QSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLL 941
+ +L ++ + + E ++++W+ R YL + A+ L + Q + LL
Sbjct: 267 RKELESILSYPPSEELSLEEKDLIWKFRFYLTRNKKAMTKFLKSVVWTDSSEVNQALSLL 326
Query: 942 RLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXX 1001
W + +A+ LL P F VR A L S+++L L L Q ++ Y
Sbjct: 327 DSWTEIDIDDALELLSPSFVHPKVRAYAVSRLETASNEEL---LLYLLQLVQALRYDNPI 383
Query: 1002 XXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSAS 1061
S P+I + +L + +ED E + + +S
Sbjct: 384 SSDERFQPSPLALFLVNRAI-----SSPSIGNDLYW-YLVVEIED------EPVSKLFSS 431
Query: 1062 WRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXX 1121
+ + G + +TL Q V+ L ++ SV+ +
Sbjct: 432 VMFLFQKELSKSVEGRLIRETLSAQAKFVEKLLRISKSVQSFRGTRLKKIEYLKVLLEDH 491
Query: 1122 XXXXQPT-ALPLALHKYVHDLDV--KSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDL 1178
ALPL L V+ + + +CT F S PL++ F D + P +FK GDDL
Sbjct: 492 KYHLLDFHALPLPLDPSVNIVGIIPDACTVFKSTMQPLRLLFKCQDGSKYPIIFKNGDDL 551
Query: 1179 RQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLT 1238
RQD LV+Q++ +MD L K LDL + ++ L T + G ++ V ++TL I E+
Sbjct: 552 RQDQLVIQILTLMDKLLKKEKLDLHLKPYRILATGPTHGAVQFVP-SKTLATILAEYH-- 608
Query: 1239 GSFKDKPIAEWLAKHNPSE----LEY---QRARDNFTASCAGYSVATYLLGICDRHNDNI 1291
GS + +L ++NP + Y A DN+ SCAGY V TYLLG+ DRH DN+
Sbjct: 609 GS-----VLAYLRENNPDDGLNSANYGIDPVAMDNYVRSCAGYCVITYLLGVGDRHLDNL 663
Query: 1292 MLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQH 1350
++ GH FH DFG LG D ++F + L+ +MV + G P +Q
Sbjct: 664 LITKDGHFFHADFGYILGRDPKLFSPAMK----------LSKEMVEGMGGYNSPF--YQQ 711
Query: 1351 FVELCCMAFNIVRAHHDHILDLFAL 1375
F C F +R + IL+LF+L
Sbjct: 712 FKSYCYTTFTALRKSSNLILNLFSL 736
>UniRef50_Q8NEB9 Cluster: Phosphatidylinositol 3-kinase catalytic
subunit type 3; n=37; Eukaryota|Rep: Phosphatidylinositol
3-kinase catalytic subunit type 3 - Homo sapiens (Human)
Length = 887
Score = 138 bits (334), Expect = 1e-30
Identities = 84/246 (34%), Positives = 130/246 (52%), Gaps = 16/246 (6%)
Query: 1130 LPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIK 1189
LPL + + ++ T F S +P ++ F D P +FK GDDLRQD L+LQ+I
Sbjct: 593 LPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIIS 652
Query: 1190 IMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEW 1249
+MD L K LDL++ ++ L TS G ++ + + TE + F+ +E
Sbjct: 653 LMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSE- 711
Query: 1250 LAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLG 1309
+ P+ + + D + SCAGY V TY+LG+ DRH DN++L +G LFHIDFG LG
Sbjct: 712 ---NGPNGISAE-VMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILG 767
Query: 1310 DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHI 1369
+ K L P L +MV + G + ++++Q F + C AF +R + + I
Sbjct: 768 -----RDPKPL----PPPMKLNKEMVEGMGGTQ--SEQYQEFRKQCYTAFLHLRRYSNLI 816
Query: 1370 LDLFAL 1375
L+LF+L
Sbjct: 817 LNLFSL 822
Score = 51.6 bits (118), Expect = 2e-04
Identities = 38/134 (28%), Positives = 64/134 (47%), Gaps = 4/134 (2%)
Query: 867 SLKDLPSFDSL--DGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLL 924
SL+ PS L + T+ QL ++ +++ E ++++W+ R YL AL L
Sbjct: 276 SLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTK-FL 334
Query: 925 AATNW-YGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983
NW +Q + LL W+ +++ LL + + VR A L + D+DL
Sbjct: 335 KCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLM 394
Query: 984 VLPQLTQALRHETY 997
L QL QAL++E +
Sbjct: 395 YLLQLVQALKYENF 408
>UniRef50_UPI0000DB7C6C Cluster: PREDICTED: similar to
Phosphotidylinositol 3 kinase 59F CG5373-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Phosphotidylinositol
3 kinase 59F CG5373-PA - Apis mellifera
Length = 774
Score = 138 bits (333), Expect = 1e-30
Identities = 87/254 (34%), Positives = 130/254 (51%), Gaps = 24/254 (9%)
Query: 1126 QPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVL 1185
+P PL + + + + F S +P K+ F+ DN+ A+FK GDDLRQD L+L
Sbjct: 476 EPIPFPLDPEISIKGIIPEKASLFKSALMPSKLTFLTMDNSEYIAIFKHGDDLRQDQLIL 535
Query: 1186 QVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKP 1245
Q I +MD L + LDL++ ++ L TS G ++ + + +E + F+
Sbjct: 536 QTIALMDKLLRRENLDLKLTPYRVLATSTRHGFLQFIESTTVAEVLASEGSILSFFR--- 592
Query: 1246 IAEWLAKHNPSEL----EYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFH 1301
KH+PSE D + SCAGY + TY+LG+ DRH DN++L TSG LFH
Sbjct: 593 ------KHHPSENGPYGVVPEVMDTYVRSCAGYCIITYVLGVGDRHLDNLLLTTSGKLFH 646
Query: 1302 IDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNI 1361
IDFG LG + K L P L+ +MV + G ++ + F + C AF
Sbjct: 647 IDFGYILG-----RDPKPL----PPPMKLSKEMVEAMGG--VGSEHYHEFRKQCYTAFLH 695
Query: 1362 VRAHHDHILDLFAL 1375
+R H + IL+LF+L
Sbjct: 696 LRRHANLILNLFSL 709
Score = 65.7 bits (153), Expect = 9e-09
Identities = 40/103 (38%), Positives = 56/103 (54%), Gaps = 4/103 (3%)
Query: 897 MPTECREVMWEKRQYLVQIPGALPLVLLAATNWY--GDHREQLIGLLRLWEKPSPLNAMH 954
+ TE ++++W+ R YL AL + NW G+ R Q + +L LW P P +A+
Sbjct: 287 LSTEEQDLIWKYRFYLSNQKKALTK-FVKCVNWKVAGEER-QALEMLALWAPPDPEDALE 344
Query: 955 LLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
LL P F AVR A LN+ DDDL L QL QAL++E +
Sbjct: 345 LLGPAFTHTAVRRYAITRLNQAPDDDLMLYLLQLVQALKYEDF 387
>UniRef50_Q5KM37 Cluster: Phosphatidylinositol 3-kinase, putative;
n=1; Filobasidiella neoformans|Rep: Phosphatidylinositol
3-kinase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 918
Score = 136 bits (330), Expect = 3e-30
Identities = 148/507 (29%), Positives = 219/507 (43%), Gaps = 47/507 (9%)
Query: 897 MPTECREVMWEKRQYLVQIPGALPLVLLAATNWYG--DHREQLIGLLRLWEKPSPLN-AM 953
+ T ++++W+ R L + P +L L T W + ++ + LL LW + ++ A+
Sbjct: 368 LSTVDKDLLWKFRFSLFRSPRSLTKFLKCIT-WSDPVEAKQAVEKLLPLWGQEVGMDDAL 426
Query: 954 HLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXX 1013
LL P F VR A K L DD+L L QL QAL+ E
Sbjct: 427 ELLGPNFTHKKVRAFAVKRLERAEDDELLLYLLQLVQALKFEHKSSLDVQRGHRSHRKRE 486
Query: 1014 XXXXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNAS---ENAETDASMSASWRYTLMLRA 1070
S I ++ LG + +N + M A + M +
Sbjct: 487 RELASQDEQGSGLSQFLINRSVANPILGTSFHWYLMIECDNRSSVGKMYAQVAFNFMKKL 546
Query: 1071 LLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXX----XXXXQ 1126
V + L RQ LV+ L A ++ +K+ +
Sbjct: 547 SEV--SQAQRDILRRQGELVQILSTRAKDIRASKDSRSKKIEKLKAYLSDSKHGLASLPE 604
Query: 1127 PTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDN----------AVI------PA 1170
P LPL + +V + + + F SN LPL I F D+ AV+ P
Sbjct: 605 PLPLPLNANIFVTSVVAEKSSIFKSNLLPLLIWFETIDSTRPTDDDSPDAVVSITPDYPI 664
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK GDDLRQD LV+Q+ +MD L K LDLR+ + L TS ++GMI+ V ++++ +
Sbjct: 665 IFKNGDDLRQDQLVIQLFTLMDRLLRKENLDLRLSPYSVLATSTTEGMIQFVP-SKSVAS 723
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
I E G ++ A+ A + +E D F SCAGYSV TY+LG+ DRH DN
Sbjct: 724 IMAEHGSLQNYLRIEHADDGALGSYG-IEAS-VMDTFVRSCAGYSVLTYVLGVGDRHLDN 781
Query: 1291 IMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVING-GERPTQRF 1348
+ML GH FH+DFG LG D + + P + +MV + G G RF
Sbjct: 782 LMLAPDGHFFHVDFGYILGRDPKPY----------PPPVKVCKEMVDAMGGPGSAHYGRF 831
Query: 1349 QHFVELCCMAFNIVRAHHDHILDLFAL 1375
Q LC AF +R + + IL+L AL
Sbjct: 832 Q---SLCYTAFIGLRKNANLILNLVAL 855
>UniRef50_Q7RSM1 Cluster: Phosphatidylinositol 3-kinase vps34-like;
n=5; Plasmodium (Vinckeia)|Rep: Phosphatidylinositol
3-kinase vps34-like - Plasmodium yoelii yoelii
Length = 1686
Score = 136 bits (329), Expect = 4e-30
Identities = 78/212 (36%), Positives = 118/212 (55%), Gaps = 17/212 (8%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
++K GDDLRQD LV+QVI I+D +W K GL+L++ ++ L S + G IE V AE++ +
Sbjct: 1432 IYKAGDDLRQDHLVIQVIYIIDNIWKKYGLNLKLTLYRVLALSTNDGFIEFVDYAESISS 1491
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
I+ + G + I K+ P + + +NF +SCAGYSV TY+LGI DRH DN
Sbjct: 1492 IKKNYN--GEIRQYFIHHSNEKNTPLGFDTE-ILENFISSCAGYSVITYILGIGDRHLDN 1548
Query: 1291 IMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQ 1349
+M+ G FHIDFG G D + F P L +M+ + G + + ++
Sbjct: 1549 LMVSNDGRFFHIDFGYIFGEDPKPFS----------PPMKLCKEMIEAMGGAQ--SVGYE 1596
Query: 1350 HFVELCCMAFNIVRAHHDHILDLFALPSCDSG 1381
F++ CC+A+ +R H I+ L C+SG
Sbjct: 1597 QFLKKCCLAYKYLRYHSTLIISLLD-SMCESG 1627
>UniRef50_Q6C299 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 801
Score = 136 bits (329), Expect = 4e-30
Identities = 89/258 (34%), Positives = 134/258 (51%), Gaps = 23/258 (8%)
Query: 1127 PTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQ 1186
P LPL + + +D C+ F S+ PLK+ F D ++ P +FK GDDLRQD LV+Q
Sbjct: 493 PVILPLDPTQRIVGIDENDCSVFKSSLTPLKLTFKMEDGSLYPIIFKSGDDLRQDQLVIQ 552
Query: 1187 VIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEW--GLTGSFKDK 1244
+I +M+ L L LDL++ ++ L T G I+ V +TL ++ +++ G+ K+K
Sbjct: 553 IITLMNQLLLNENLDLKITPYRILATGAVDGAIQFVPN-QTLASVLSDYPGGILQFLKEK 611
Query: 1245 -PIA-EWLAKHNPSELEY---QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHL 1299
P+ E A P L D F SCAGY V TY+LG+ DRH DN+++ GH
Sbjct: 612 APMTEEQQALLPPGSLSLGVRPEVMDTFVRSCAGYCVMTYILGVGDRHLDNLLISDDGHF 671
Query: 1300 FHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVING-GERPTQRFQHFVELCCM 1357
FH DFG LG D + F +L + +I+G G ++ + F C
Sbjct: 672 FHADFGYILGRDPKPFPPLMKL-------------PIQIIDGMGGIHSENYTKFRNYCFT 718
Query: 1358 AFNIVRAHHDHILDLFAL 1375
A+ +R + IL+LF+L
Sbjct: 719 AYTTLRKSANLILNLFSL 736
Score = 40.3 bits (90), Expect = 0.40
Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 1/102 (0%)
Query: 895 QRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMH 954
Q + + ++W+ R Y + AL L + + Q I LL +W++ +A+
Sbjct: 280 QELTENEKNLLWKFRYYATRDKRALTKFLKSVSWDDASEMRQAIALLPMWKEVDISDALE 339
Query: 955 LLLPCFPD-VAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
+L P F D AVR A L D +L L QL QAL+ +
Sbjct: 340 MLGPGFADHPAVRAFAVDRLRASPDKELELYLLQLVQALQFD 381
>UniRef50_Q8I3V5 Cluster: Phosphatidylinositol 3-kinase, putative;
n=1; Plasmodium falciparum 3D7|Rep: Phosphatidylinositol
3-kinase, putative - Plasmodium falciparum (isolate 3D7)
Length = 2133
Score = 135 bits (326), Expect = 1e-29
Identities = 77/212 (36%), Positives = 114/212 (53%), Gaps = 17/212 (8%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
++K GDDLRQD LV+Q+I +MD +W + GLDL+M ++ L S G IE V AE++ +
Sbjct: 1879 IYKAGDDLRQDHLVIQIIYVMDNIWKRYGLDLKMTLYRVLALSTDDGFIEFVDYAESISS 1938
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
I+ + G + I +P + + NF +SCAGYSV TY+LGI DRH DN
Sbjct: 1939 IKKNY--KGEIRQYFIDNSTCSSSPLGFDTE-ILQNFISSCAGYSVITYILGIGDRHLDN 1995
Query: 1291 IMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQ 1349
+M+ G FHIDFG G D + F P L +M+ + G + ++
Sbjct: 1996 LMVTKDGRFFHIDFGYIFGEDPKPFS----------PPMKLCKEMIEAMGGAH--SIGYE 2043
Query: 1350 HFVELCCMAFNIVRAHHDHILDLFALPSCDSG 1381
F++ CC+A+ +R H I+ L CD+G
Sbjct: 2044 QFLKKCCLAYKYLRYHSQLIISLLD-AMCDAG 2074
>UniRef50_Q2PF84 Cluster: Phosphatidylinositol 4-kinase; n=1; Pichia
pastoris|Rep: Phosphatidylinositol 4-kinase - Pichia
pastoris (Yeast)
Length = 1837
Score = 134 bits (323), Expect = 2e-29
Identities = 82/215 (38%), Positives = 123/215 (57%), Gaps = 15/215 (6%)
Query: 1168 IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAET 1227
I A+FKVGDD RQD L LQ+I + T+W+ +G+DL + ++ T+ G+I+++ + +
Sbjct: 1580 ISAIFKVGDDCRQDVLALQLISLFRTIWMNSGVDLYVFPYKVTATAPGCGVIDVLPNSVS 1639
Query: 1228 LRAIQTEWGLTGSFKDKPIAEWLAKHNP-SELEYQRARDNFTASCAGYSVATYLLGICDR 1286
+ E + G ++ +++K P + E+Q+AR NF S A YSV +YLL DR
Sbjct: 1640 RDMLGRE-AVNGLYE-----YFISKFGPETSSEFQKARANFVKSLAAYSVISYLLQFKDR 1693
Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346
HN NIM + GH+ HIDFG F D G V +++PF LT +MV V+ GG TQ
Sbjct: 1694 HNGNIMYDSEGHILHIDFG-FCFDIVPGG-----VKFEQSPFKLTKEMVNVM-GGNTSTQ 1746
Query: 1347 RFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSG 1381
++ F ELC AF R + + I+ +P DSG
Sbjct: 1747 AYRWFEELCVKAFLSARPYMETIVRCI-VPMLDSG 1780
>UniRef50_Q6C4B9 Cluster: Yarrowia lipolytica chromosome E of strain
CLIB 122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome E of
strain CLIB 122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 1857
Score = 133 bits (322), Expect = 3e-29
Identities = 82/213 (38%), Positives = 121/213 (56%), Gaps = 15/213 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I + +++ G+DL + ++ T+ G+I+++ ++ +
Sbjct: 1602 AIFKVGDDCRQDVLALQIISVFRSIFNSYGMDLYVFPYRVTATAPGCGVIDVLPDSISRD 1661
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKHNPSE-LEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
+ E + G ++ + +KH + +++QRAR+NF S A YSV +YL+ DRHN
Sbjct: 1662 MLGRE-AVNGLYE-----YFTSKHGSEDSIQFQRARNNFVKSLAAYSVISYLIQFKDRHN 1715
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
NIM GH+ HIDFG F D G V + APF LTH+MV V+ GG TQ +
Sbjct: 1716 GNIMYDGQGHILHIDFG-FCFDIVPGG-----VKFEAAPFKLTHEMVLVM-GGNTQTQAY 1768
Query: 1349 QHFVELCCMAFNIVRAHHDHILDLFALPSCDSG 1381
+ F EL AF R H + I+ L LP DSG
Sbjct: 1769 RWFEELSVKAFLACRPHAETIIQL-VLPMLDSG 1800
>UniRef50_P22543 Cluster: Phosphatidylinositol 3-kinase VPS34; n=5;
Saccharomycetales|Rep: Phosphatidylinositol 3-kinase
VPS34 - Saccharomyces cerevisiae (Baker's yeast)
Length = 875
Score = 133 bits (321), Expect = 4e-29
Identities = 92/256 (35%), Positives = 133/256 (51%), Gaps = 28/256 (10%)
Query: 1126 QPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVL 1185
+P ALPL + D+ ++ F S+ PLKI F T N MFKVGDDLRQD LV+
Sbjct: 577 RPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVV 636
Query: 1186 QVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEW-GLTGSFKDK 1244
Q+I +M+ L +DL++ ++ L T +G IE + +TL +I +++ G+ G
Sbjct: 637 QIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPN-DTLASILSKYHGILG----- 690
Query: 1245 PIAEWLAKHNPSE---LEYQR-ARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLF 1300
+L H P E L Q DNF SCAGY V TY+LG+ DRH DN+++ GH F
Sbjct: 691 ----YLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFF 746
Query: 1301 HIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAF 1359
H DFG LG D + F + L ++ G E + + F C +A+
Sbjct: 747 HADFGYILGQDPKPFPPLMK----------LPPQIIEAFGGAE--SSNYDKFRSYCFVAY 794
Query: 1360 NIVRAHHDHILDLFAL 1375
+I+R + IL+LF L
Sbjct: 795 SILRRNAGLILNLFEL 810
Score = 38.3 bits (85), Expect = 1.6
Identities = 26/91 (28%), Positives = 45/91 (49%)
Query: 905 MWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVA 964
+W+ R YL+ AL +L + R +++ L+ W + +A+ LL F +++
Sbjct: 327 IWKYRYYLMNNKKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLS 386
Query: 965 VRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
VR A L + SD +L L QL +A+ E
Sbjct: 387 VRSYAVNRLKKASDKELELYLLQLVEAVCFE 417
>UniRef50_A5K9K5 Cluster: Phosphatidylinositol 3-kinase, putative;
n=1; Plasmodium vivax|Rep: Phosphatidylinositol 3-kinase,
putative - Plasmodium vivax
Length = 1779
Score = 132 bits (320), Expect = 5e-29
Identities = 79/213 (37%), Positives = 117/213 (54%), Gaps = 19/213 (8%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
++K GDDLRQD LV+Q+I I+D +W + GLDL++ ++ L S G IE V AE++ +
Sbjct: 1525 IYKAGDDLRQDHLVIQIICIIDNIWKRYGLDLKLTLYKVLALSTDDGFIEFVNYAESISS 1584
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRA-RDNFTASCAGYSVATYLLGICDRHND 1289
I+ + G + I ++ + S L + DNF +SCAGYSV TYLLGI DRH D
Sbjct: 1585 IKKNY--KGEIRQYFIE--MSTDSKSPLGFDAIILDNFISSCAGYSVITYLLGIGDRHLD 1640
Query: 1290 NIMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
N+M+ G FHIDFG G D + F P L +M+ + G + +
Sbjct: 1641 NLMVSRDGCFFHIDFGYIFGEDPKPFS----------PPMKLCKEMIEAMGGAH--SVGY 1688
Query: 1349 QHFVELCCMAFNIVRAHHDHILDLFALPSCDSG 1381
+ F++ CC+A+ +R H I+ L C+SG
Sbjct: 1689 EQFLKKCCLAYKYLRYHSKLIISLLDC-MCESG 1720
>UniRef50_UPI0000EBCA07 Cluster: PREDICTED: similar to
phosphoinositide-3-kinase, class 2, gamma polypeptide,
partial; n=3; Bos taurus|Rep: PREDICTED: similar to
phosphoinositide-3-kinase, class 2, gamma polypeptide,
partial - Bos taurus
Length = 965
Score = 132 bits (319), Expect = 7e-29
Identities = 98/320 (30%), Positives = 143/320 (44%), Gaps = 30/320 (9%)
Query: 900 ECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPC 959
E R +W R Y +LPLVL +A W ++ +LR W+ PL A+ LL
Sbjct: 673 EKRRYLWFYRFYCNNENCSLPLVLGSAPGWDERTVSEMHTILRRWKFSHPLEALGLLTSS 732
Query: 960 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 1019
FPD +R A + L+ + +D+L LPQL QA++ E
Sbjct: 733 FPDQEIRNVAVQQLDNLLNDELLEYLPQLVQAVKFEWNLESPLVQLLLHRSLQSVQIAHR 792
Query: 1020 XFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENL 1079
+WLL ++A+ +A W Y +L AL G+ L
Sbjct: 793 LYWLL-------------------------KDAQNEAYFKI-W-YQKLLAALQFCAGKAL 825
Query: 1080 NKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTA-LPLALHKYV 1138
++Q L+K L ++ VK A + T LPL V
Sbjct: 826 RDEFSKEQKLIKILGDIGEKVKTASDPQRQEVLKKELGRLEEFFWCTKTCHLPLNPALCV 885
Query: 1139 HDLDVKSCTYFSSNTLPLKINFIGTD--NAVIPAMFKVGDDLRQDALVLQVIKIMDTLWL 1196
+D +C+YF+SN LPLKI FI + I +FK GDDLRQD LVLQ+I++MD +WL
Sbjct: 886 QGIDGDACSYFTSNALPLKITFINANPMGKNISVIFKAGDDLRQDMLVLQIIQVMDNIWL 945
Query: 1197 KAGLDLRMVTFQALPTSNSK 1216
+ GLD++MV ++ L T +
Sbjct: 946 QEGLDMQMVIYRCLSTGKGQ 965
>UniRef50_Q6CUT6 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome C of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome C of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 956
Score = 132 bits (319), Expect = 7e-29
Identities = 82/218 (37%), Positives = 117/218 (53%), Gaps = 18/218 (8%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDLRQ+A Q+I+ M +W K + + + L TS+ G++E +T A ++ +I+
Sbjct: 686 KSGDDLRQEAFACQLIQAMAAIWSKENVGVWVKKMNILITSSHTGLVETITNAISVHSIK 745
Query: 1233 ----TEWGLTGSFKDKPIAEWLAKH------NPSELEYQRARDNFTASCAGYSVATYLLG 1282
T GS +K L H +P+ +++ A+DNF +S A YS+ YLL
Sbjct: 746 KSLTTHMIEEGSLDEKGDIASLLDHFSRVYGDPNGFKFRHAQDNFASSLAAYSIICYLLR 805
Query: 1283 ICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGE 1342
I DRHN NIM+ GH+ HIDFG M N V + APF LT++ V V+ G E
Sbjct: 806 IKDRHNGNIMIDNEGHVVHIDFG------FMLSNSPGSVGFEAAPFKLTYEYVEVMGGSE 859
Query: 1343 RPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
T F+ FVELC AF +R + DHI+ L + DS
Sbjct: 860 SET--FKKFVELCKAAFKALRKYADHIVSLCEIMQKDS 895
>UniRef50_Q7PMF0 Cluster: ENSANGP00000002906; n=2; Coelomata|Rep:
ENSANGP00000002906 - Anopheles gambiae str. PEST
Length = 924
Score = 132 bits (318), Expect = 9e-29
Identities = 88/253 (34%), Positives = 125/253 (49%), Gaps = 24/253 (9%)
Query: 1127 PTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQ 1186
P PL + + + + F S +P K+ F T A+FK GDDLRQD L+LQ
Sbjct: 627 PIVFPLDPSIQITGIAAEKVSLFKSALMPSKLTFRTTSGTDYVAIFKHGDDLRQDQLILQ 686
Query: 1187 VIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPI 1246
+I +MD L K LDL++ ++ L TS+ G ++ + + TE + F+
Sbjct: 687 MITLMDKLLQKENLDLKLTPYRVLATSSKHGFMQYIDSVTVAEVLNTEGSIHNYFR---- 742
Query: 1247 AEWLAKHNPSELE----YQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHI 1302
K NP E D + SCAGY V TYLLGI DRH DN++L +SG LFHI
Sbjct: 743 -----KFNPCETGPFGIMPEIMDTYIKSCAGYCVITYLLGIGDRHLDNLLLTSSGKLFHI 797
Query: 1303 DFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIV 1362
DFG LG K + P L+ +MV + G ++ + F +LC AF +
Sbjct: 798 DFGYILGRDP-----KPMP----PPMKLSKEMVEAMGGIN--SEYYNTFRKLCYTAFLHL 846
Query: 1363 RAHHDHILDLFAL 1375
R H + +L+LF L
Sbjct: 847 RRHANVMLNLFGL 859
Score = 47.2 bits (107), Expect = 0.003
Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Query: 897 MPTECREVMWEKRQYLVQIPGALPLVLLAATNWY-GDHREQLIGLLRLWEKPSPLNAMHL 955
+ +E ++++W+ R YL AL L NW Q + LL W +A+ L
Sbjct: 309 LSSEEQDIIWKYRFYLSSHKKALTK-FLKCVNWETAAEVRQALALLESWSPMDVEDALEL 367
Query: 956 LLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
L F VR A LNE SD+ L L QL QAL++E +
Sbjct: 368 LNSTFRHPIVRWYAITRLNEASDEYLLLYLLQLVQALKYEPF 409
>UniRef50_Q75AF0 Cluster: ADL033Wp; n=3; Saccharomycetaceae|Rep:
ADL033Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 1916
Score = 131 bits (316), Expect = 2e-28
Identities = 81/213 (38%), Positives = 115/213 (53%), Gaps = 15/213 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I + T+W G+D+ + ++ T+ G+I+++ + +
Sbjct: 1660 AIFKVGDDCRQDVLALQLISVFRTIWASIGMDVYVFPYRVTATAPGCGVIDVLPNSISRD 1719
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKHNP-SELEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
+ E + G ++ + K P + +E++ AR+NF S A YSV +YLL DRHN
Sbjct: 1720 MLGRE-AVNGLYE-----YFTTKFGPENSIEFEHARNNFVKSLAAYSVISYLLQFKDRHN 1773
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
NIM GH HIDFG F+ D G V + PF LT +MV V+ GG TQ +
Sbjct: 1774 GNIMYDEHGHCLHIDFG-FIFDIVPGG-----VKFEAVPFKLTKEMVRVM-GGSPDTQAY 1826
Query: 1349 QHFVELCCMAFNIVRAHHDHILDLFALPSCDSG 1381
Q F ELC A+ R H D I+ LP SG
Sbjct: 1827 QRFQELCTKAYLAARPHMDTIVQC-VLPMLGSG 1858
>UniRef50_Q6CQA2 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome D of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=2; cellular organisms|Rep: Kluyveromyces lactis
strain NRRL Y-1140 chromosome D of strain NRRL Y- 1140 of
Kluyveromyces lactis - Kluyveromyces lactis (Yeast)
(Candida sphaerica)
Length = 862
Score = 129 bits (312), Expect = 5e-28
Identities = 98/307 (31%), Positives = 145/307 (47%), Gaps = 29/307 (9%)
Query: 1077 ENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXXXXXX-QPTALPLALH 1135
E+ KT+ Q LLV L + +K +KE + A+ L L
Sbjct: 512 EHSKKTIDDQILLVDMLRKFCEEIKQSKETTVKKQEILLHLISSRMRSLFKNKAITLPLD 571
Query: 1136 KYVHDLDV--KSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDT 1193
V +DV SC F S+ PLKI F+ + MFKVGDDL QD LV+Q+IK+MD
Sbjct: 572 PDVIAVDVIPSSCKVFKSSLSPLKITFLTANGQHYSLMFKVGDDLIQDQLVVQIIKLMDQ 631
Query: 1194 LWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKH 1253
L +DL++ + L T ++G I + ET+ +I + I ++L ++
Sbjct: 632 LLKNENVDLKLTPYNILATGKNEGAIGFIPN-ETMSSILS--------VHHGILKYLQQN 682
Query: 1254 NPSELEYQRAR----DNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLG 1309
PS+ E DNF SCAGY V TY+LG+ DRH DN++++ G FH DFG LG
Sbjct: 683 YPSQAEIDGVEPWVMDNFVKSCAGYCVITYILGVGDRHLDNLLIQPDGKFFHADFGYILG 742
Query: 1310 -DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDH 1368
D + F P + + GG + + F C +A++I+R +
Sbjct: 743 YDPKPF-----------PPLMKLPPQIIEAFGG-TDSANYDKFRSYCFVAYSILRRNAGL 790
Query: 1369 ILDLFAL 1375
I++LF L
Sbjct: 791 IINLFEL 797
Score = 40.3 bits (90), Expect = 0.40
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 904 VMWEKRQYLVQIPGALPLVLLAATNWYGDHR-EQLIGLLRLWEKPSPLNAMHLLLPCFPD 962
++W+ R YL AL LL +TN + ++++ L+ +W + + M LL P + +
Sbjct: 324 LIWKYRYYLSNNKKAL-TKLLQSTNLSEESEIKEVLDLMDIWAEIDLDDTMELLGPQYTN 382
Query: 963 VAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
++VR A L + SD++L L QL Q++ E
Sbjct: 383 ISVRSYAVNRLRKASDNELELYLLQLVQSVCFE 415
>UniRef50_Q9W4X4 Cluster: CG10260-PB; n=4; Sophophora|Rep: CG10260-PB
- Drosophila melanogaster (Fruit fly)
Length = 2178
Score = 129 bits (311), Expect = 7e-28
Identities = 83/208 (39%), Positives = 117/208 (56%), Gaps = 16/208 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD+RQD L LQVI I ++ + GLDL + ++ + T+ G+IE V A++
Sbjct: 1923 AIFKVGDDVRQDMLALQVITIFKNIFQQVGLDLFLFPYRVVATAPGCGVIECVPNAKSRD 1982
Query: 1230 AI--QTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287
+ QT+ GL+ F+ + E S E+Q AR NF S A YS+ YLL I DRH
Sbjct: 1983 QLGRQTDSGLSEYFQHQYGDE-------SSKEFQAARANFVKSMAAYSLIGYLLQIKDRH 2035
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
N NIM+ GH+ HIDFG F+ ++ GN I P + D + +I GG+ +
Sbjct: 2036 NGNIMIDKDGHIIHIDFG-FMFESSPGGN------IGFEPDMKLTDEMVMIMGGKMDSPA 2088
Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375
F+ F ELC AF VR + D I+ L +L
Sbjct: 2089 FKWFCELCVQAFLAVRPYQDAIVSLVSL 2116
>UniRef50_P42339 Cluster: Phosphatidylinositol 3-kinase VPS34; n=16;
Magnoliophyta|Rep: Phosphatidylinositol 3-kinase VPS34 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 814
Score = 128 bits (309), Expect = 1e-27
Identities = 96/306 (31%), Positives = 143/306 (46%), Gaps = 23/306 (7%)
Query: 1076 GENLNKTLLRQQLLVKSLCEMAVSVKCAK----EXXXXXXXXXXXXXXXXXXXXQPTALP 1131
G L ++L+RQ L LC + V+ + + +P P
Sbjct: 462 GYQLWQSLVRQTELTAQLCSITREVRNVRGNTQKKIEKLRQLLGGLLSELTYFEEPIRSP 521
Query: 1132 LALHKYVHDLDVKSCTYFSSNTLPLKINF-IGTDNAVIPAMFKVGDDLRQDALVLQVIKI 1190
L + + + + F S PL++ F + +FK GDDLRQD LV+Q++ +
Sbjct: 522 LTPNVLIKGIVAGESSLFKSALHPLRLTFRTPEEGGSCKLIFKKGDDLRQDQLVVQMVWL 581
Query: 1191 MDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWL 1250
MD L LDL + ++ L T + +GM+E + + +L I +E S+ K +
Sbjct: 582 MDRLLKLENLDLCLTPYKVLATGHDEGMLEFIP-SRSLAQILSEHRSITSYLQKFHPD-- 638
Query: 1251 AKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLG- 1309
+H P + D F SCAGYSV TY+LGI DRH DN++L G LFH+DF LG
Sbjct: 639 -EHAPFGIT-ATCLDTFIKSCAGYSVITYILGIGDRHLDNLLLTDDGRLFHVDFAFILGR 696
Query: 1310 DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHI 1369
D + F P L +MV + G E +Q + F CC A+NI+R + I
Sbjct: 697 DPKPF----------PPPMKLCKEMVEAMGGAE--SQYYTRFKSYCCEAYNILRKSSNLI 744
Query: 1370 LDLFAL 1375
L+LF L
Sbjct: 745 LNLFHL 750
Score = 45.6 bits (103), Expect = 0.011
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 902 REVMWEKRQYLVQIPGALPLVLLAATNWYG-DHREQLIGLLRLWEKPSPLNAMHLLLPCF 960
R+++W+ R L+ AL L W +Q I L+ WE +A+ LL P F
Sbjct: 304 RQLLWKFRFSLMSEKRALTK-FLRCVEWSDVQEAKQAIQLMYKWEMIDVCDALELLSPLF 362
Query: 961 PDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
VR A +L D++L L QL QALR E
Sbjct: 363 ESEEVRAYAVSVLERADDEELQCYLLQLVQALRFE 397
>UniRef50_Q94125 Cluster: Phosphatidylinositol 3-kinase age-1; n=3;
Caenorhabditis|Rep: Phosphatidylinositol 3-kinase age-1 -
Caenorhabditis elegans
Length = 1182
Score = 128 bits (308), Expect = 2e-27
Identities = 85/237 (35%), Positives = 116/237 (48%), Gaps = 36/237 (15%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK GDDLRQD LVLQV+++MD +W A +D + + LP G+IE+V +T+
Sbjct: 888 IFKNGDDLRQDMLVLQVLEVMDNIWKAANIDCCLNPYAVLPMGEMIGIIEVVPNCKTIFE 947
Query: 1231 IQTEWGLTG----SFKDKPIAEWLAKH----------------NPSELE---------YQ 1261
IQ G S + +W+ K NP E + Y
Sbjct: 948 IQVGTGFMNTAVRSIDPSFMNKWIRKQCGIEDEKKKSKKDSTKNPIEKKIDNTQAMKKYF 1007
Query: 1262 RARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLV 1321
+ D F SC GYSVATY++GI DRH+DN+ML G FHIDFG LG G K +
Sbjct: 1008 ESVDRFLYSCVGYSVATYIMGIKDRHSDNLMLTEDGKYFHIDFGHILG----HGKTKLGI 1063
Query: 1322 YIDRAPFVLTHDMVYVINGG---ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
DR PF+LT + VI G + + Q F LC A+ ++ + D + LF L
Sbjct: 1064 QRDRQPFILTEHFMTVIRSGKSVDGNSHELQKFKTLCVEAYEVMWNNRDLFVSLFTL 1120
>UniRef50_Q57YM2 Cluster: Phosphatidylinositol 3-kinase, putative;
n=4; Trypanosoma|Rep: Phosphatidylinositol 3-kinase,
putative - Trypanosoma brucei
Length = 949
Score = 127 bits (307), Expect = 2e-27
Identities = 74/206 (35%), Positives = 116/206 (56%), Gaps = 24/206 (11%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FKVGDD+RQD LV+Q+++++D + + GLDL + ++ + T ++G++E++ TL++
Sbjct: 698 LFKVGDDVRQDQLVVQLVQLIDMILRQDGLDLCLCPYRVIATGPTEGLVELIPNVVTLQS 757
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
+Q + +TG + + N S+ Y A FT SCAGY V T++LGI DRH +N
Sbjct: 758 VQRD--ITGFIRSR---------NQSQEGYTAAMSRFTKSCAGYCVLTFILGIGDRHLEN 806
Query: 1291 IMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQ 1349
I+L G L HIDFG LG D + F P + +MV + GG + T +
Sbjct: 807 ILLTHDGRLLHIDFGYILGNDPKPF----------PPPMKINKEMVEAL-GGPQST-GYM 854
Query: 1350 HFVELCCMAFNIVRAHHDHILDLFAL 1375
F CC ++NI+R H IL + L
Sbjct: 855 EFKSYCCSSYNIIREHAQVILSMLLL 880
>UniRef50_UPI00004993D5 Cluster: phosphatidylinositol 3-kinase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: phosphatidylinositol
3-kinase - Entamoeba histolytica HM-1:IMSS
Length = 849
Score = 127 bits (306), Expect = 3e-27
Identities = 91/260 (35%), Positives = 132/260 (50%), Gaps = 36/260 (13%)
Query: 1129 ALPLALHKYVHDLDVKSCTYFSSNTLPLKINFI------------GTDNAVIPAMFKVGD 1176
ALPL YV ++ KS F SN PLK+ FI +N + K GD
Sbjct: 534 ALPLNPRVYVKGINPKSSYIFKSNKAPLKLPFIVDTEKTKTKGKINYENKEFIVIVKHGD 593
Query: 1177 DLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWG 1236
DLRQD L++Q+I +MD L K +DL++ + + TS GM+E + G
Sbjct: 594 DLRQDQLIVQMIALMDNLLKKDLMDLKLTPYHVVATSPVDGMVEFIPSD----------G 643
Query: 1237 LTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTS 1296
+ KD + ++L K N + Q +NF S AG SV TYLLG+ DRH DN++++ +
Sbjct: 644 MGDIIKDGTLRDYLMKMNGGSIPTQ-VMNNFIRSVAGNSVITYLLGVGDRHLDNLLVRGN 702
Query: 1297 GHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELC 1355
G +FHIDFG LG + + F P L ++V + GG+ TQ +Q F +LC
Sbjct: 703 GVMFHIDFGYILGKECKPF----------PPPMKLCKEIVECM-GGKGSTQ-YQDFTKLC 750
Query: 1356 CMAFNIVRAHHDHILDLFAL 1375
C +N +R I++LF L
Sbjct: 751 CECYNSIRKSSKLIMNLFQL 770
>UniRef50_UPI0000DB7272 Cluster: PREDICTED: similar to CG10260-PB
isoform 2; n=2; Endopterygota|Rep: PREDICTED: similar to
CG10260-PB isoform 2 - Apis mellifera
Length = 2093
Score = 126 bits (305), Expect = 4e-27
Identities = 80/208 (38%), Positives = 111/208 (53%), Gaps = 16/208 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD+RQD L LQVI I ++ K GL+L + ++ + T+ G+IE V A
Sbjct: 1838 AIFKVGDDVRQDMLALQVISIFKNIFQKVGLNLFLFPYRVVATAPGCGVIECVPNA---- 1893
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKHNPSEL--EYQRARDNFTASCAGYSVATYLLGICDRH 1287
T G D + ++ E E+Q R NF S A YSV TYLL I DRH
Sbjct: 1894 ---TSRDQLGRTTDIDMHQYFITRYGDETTKEFQNVRRNFVKSMAAYSVITYLLQIKDRH 1950
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
N NIML T GH+ HIDFG F+ ++ GN + P + D + ++ GG+
Sbjct: 1951 NGNIMLDTEGHIIHIDFG-FMFESSPGGN------LGFEPDIKLTDEMVLVMGGKMEAAP 2003
Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375
F+ F+ELC AF VR + + I+ L +L
Sbjct: 2004 FRWFMELCVQAFLAVRPYQEAIISLVSL 2031
Score = 36.7 bits (81), Expect = 4.9
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Query: 912 LVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVR-ETAA 970
++ +P AL L T+ + +L+ +L WE+ SP+ A+ FP + + A
Sbjct: 1577 VMHVPEALQY--LVTTDTLLNDVPELVYMLT-WERVSPIQALAYFSRQFPHHPISAQYAV 1633
Query: 971 KLLNEMSDDDLCRVLPQLTQALRHET 996
++L+ D + +PQL QA+RH+T
Sbjct: 1634 EVLSSYPADAVLFYIPQLVQAVRHDT 1659
>UniRef50_P37297 Cluster: Phosphatidylinositol 4-kinase STT4; n=3;
Saccharomycetales|Rep: Phosphatidylinositol 4-kinase STT4
- Saccharomyces cerevisiae (Baker's yeast)
Length = 1900
Score = 126 bits (305), Expect = 4e-27
Identities = 77/203 (37%), Positives = 112/203 (55%), Gaps = 14/203 (6%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I + T+W GLD+ + ++ T+ G+I+++ + +
Sbjct: 1644 AIFKVGDDCRQDVLALQLISLFRTIWSSIGLDVYVFPYRVTATAPGCGVIDVLPNSVSRD 1703
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKH-NPSELEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
+ E + G ++ + +K N S +E+Q AR+NF S AGYSV +YLL DRHN
Sbjct: 1704 MLGRE-AVNGLYE-----YFTSKFGNESTIEFQNARNNFVKSLAGYSVISYLLQFKDRHN 1757
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
NIM GH HIDFG F+ D G + + PF LT +MV V+ GG T +
Sbjct: 1758 GNIMYDDQGHCLHIDFG-FIFDIVPGG-----IKFEAVPFKLTKEMVKVM-GGSPQTPAY 1810
Query: 1349 QHFVELCCMAFNIVRAHHDHILD 1371
F ELC A+ R H + I++
Sbjct: 1811 LDFEELCIKAYLAARPHVEAIIE 1833
>UniRef50_Q9XW63 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 2121
Score = 125 bits (302), Expect = 8e-27
Identities = 79/208 (37%), Positives = 115/208 (55%), Gaps = 16/208 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD+RQD L LQ++++M +W GL +R+ ++ + TS G+IE V +++
Sbjct: 1866 AIFKVGDDVRQDMLALQLMQLMKNVWAGLGLPVRVFPYRVVATSPGCGVIECVPNSKSRD 1925
Query: 1230 AI--QTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287
+ QT++GL FK + E S +Q AR NF S A YSV ++LL I DRH
Sbjct: 1926 QLGRQTDFGLYEYFKTQYGDE-------SSETFQEARRNFVRSMAAYSVFSFLLQIKDRH 1978
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
N NIM+ GH+ HIDFG F+ ++ GN F L+ +MV I GG+
Sbjct: 1979 NGNIMIDLDGHIIHIDFG-FMFESSPGGNLG-----FEPDFKLSEEMV-AIMGGKMEAAP 2031
Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375
F+ F LC A+ VR +H + L +L
Sbjct: 2032 FRQFASLCVHAYLAVRPYHKSFVSLVSL 2059
Score = 37.9 bits (84), Expect = 2.1
Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 5/87 (5%)
Query: 912 LVQIPGALPLVLLAATNWYGDHREQLIGLLRLWEKPSPLNAMHLLLP-CFPDVAVR-ETA 969
+ IP ALPL L + + + +L W + SP+ A+ LL P +P + + A
Sbjct: 1595 VAHIPEALPLFLGNGSTVF--ETSDMSHVLT-WARCSPVMALSLLTPRIYPMHPISMQYA 1651
Query: 970 AKLLNEMSDDDLCRVLPQLTQALRHET 996
++L S D+L +PQ+ QA+R++T
Sbjct: 1652 VRVLRSYSADELLLYIPQIVQAVRYDT 1678
>UniRef50_A3LYX2 Cluster: Phosphatidylinositol-4-kinase involved in
protein kinase C pathway; n=6; Fungi/Metazoa group|Rep:
Phosphatidylinositol-4-kinase involved in protein kinase
C pathway - Pichia stipitis (Yeast)
Length = 1910
Score = 125 bits (301), Expect = 1e-26
Identities = 79/202 (39%), Positives = 110/202 (54%), Gaps = 14/202 (6%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I + T+W AGLDL + + T+ G+I+++ A T R
Sbjct: 1655 AIFKVGDDCRQDVLALQLISVFRTIWTNAGLDLYVFPNRVTATAPGCGVIDVLPNA-TSR 1713
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKHNP-SELEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
+ + G ++ + K P + E+Q AR+N S A YS+ +YLL DRHN
Sbjct: 1714 DMLGREAVNGLYE-----YFTTKFGPETSPEFQTARNNLIKSLAAYSIISYLLQFKDRHN 1768
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
NIM GH+ HIDFG F D G V + APF LTH+M+ V+ GG TQ F
Sbjct: 1769 GNIMYDDQGHVLHIDFG-FCFDIVPGG-----VKFEVAPFKLTHEMIAVL-GGRIDTQAF 1821
Query: 1349 QHFVELCCMAFNIVRAHHDHIL 1370
+ F ELC + R + + I+
Sbjct: 1822 KWFEELCVKGYLACRPYMETIV 1843
>UniRef50_Q9W1M7 Cluster: CG5373-PA; n=3; Sophophora|Rep: CG5373-PA -
Drosophila melanogaster (Fruit fly)
Length = 949
Score = 124 bits (299), Expect = 2e-26
Identities = 81/251 (32%), Positives = 127/251 (50%), Gaps = 17/251 (6%)
Query: 1126 QPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGT-DNAVIPAMFKVGDDLRQDALV 1184
+P PL Y+ + + F S +P K+ F+ + + A+FK GDDLRQD L+
Sbjct: 650 EPIPFPLDPEIYITKIVPMRTSLFKSALMPAKLTFVTSIAHHEYAAIFKHGDDLRQDQLI 709
Query: 1185 LQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDK 1244
LQ+I +MD L + LDL++ ++ L TS+ G ++ V + E + F+
Sbjct: 710 LQMITLMDKLLRRENLDLKLTPYKVLATSSKHGFLQYVDSCTVAEVLAREGNIHNFFRKH 769
Query: 1245 PIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDF 1304
+ + P + + D + SCAGY V TYLLG+ DRH DN++L T+G LFHIDF
Sbjct: 770 HPCD----NGPYGISAE-VMDTYIKSCAGYCVITYLLGVGDRHLDNLLLTTNGKLFHIDF 824
Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRA 1364
G LG K + P L+ +MV + G ++ F + C A+ +R
Sbjct: 825 GYILGRDP-----KPMP----PPMKLSKEMVEAMGGIS--SEHHHEFRKQCYTAYLHLRR 873
Query: 1365 HHDHILDLFAL 1375
H + +L+LF+L
Sbjct: 874 HANVMLNLFSL 884
Score = 48.0 bits (109), Expect = 0.002
Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Query: 897 MPTECREVMWEKRQYLVQIPGALPLVLLAATNW-YGDHREQLIGLLRLWEKPSPLNAMHL 955
+ +E ++++W+ R YL AL L NW D Q + +L W +A+ L
Sbjct: 310 LSSEEQDLVWKFRFYLSSHKKALTK-FLKCINWKLEDEVTQALWMLANWAPMDVEDALEL 368
Query: 956 LLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
L P F VR+ A L + D+DL L QL QAL++E
Sbjct: 369 LSPTFTHPQVRKYAVSRLAQAPDEDLLLYLLQLVQALKYE 408
>UniRef50_UPI00015B61DA Cluster: PREDICTED: similar to
phosphatidylinositol 4-kinase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
phosphatidylinositol 4-kinase - Nasonia vitripennis
Length = 2076
Score = 123 bits (296), Expect = 4e-26
Identities = 79/208 (37%), Positives = 119/208 (57%), Gaps = 16/208 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD+RQD L LQVI I ++ + GL+L + ++ + T+ G+IE V +A++
Sbjct: 1821 AIFKVGDDVRQDMLALQVISIFKHVFEQVGLNLFLFPYRVVATAPGCGVIECVPKAKSRD 1880
Query: 1230 AI--QTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287
+ QT++GL K+ ++ + + + +Q R NF S A YSV TYLL I DRH
Sbjct: 1881 QLGRQTDYGL----KEYLLSIY---GDETSKAFQNVRRNFVKSMAAYSVITYLLQIKDRH 1933
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
N NIM+ GH+ HIDFG F+ ++ GN LT++MV V+ GG
Sbjct: 1934 NGNIMIDEEGHIIHIDFG-FMFESSPGGNLG-----FEPDIKLTNEMVLVM-GGNMEAAP 1986
Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375
F+ F+ELC AF +R + + I+ L +L
Sbjct: 1987 FRWFMELCVQAFLAIRPYQEAIISLVSL 2014
>UniRef50_P39104 Cluster: Phosphatidylinositol 4-kinase PIK1; n=5;
Fungi/Metazoa group|Rep: Phosphatidylinositol 4-kinase
PIK1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 1066
Score = 122 bits (295), Expect = 6e-26
Identities = 77/218 (35%), Positives = 120/218 (55%), Gaps = 18/218 (8%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDLRQ+A Q+I+ M +W+K +D+ + + L TS + G++E +T A ++ +I+
Sbjct: 796 KTGDDLRQEAFAYQMIQAMANIWVKEKVDVWVKRMKILITSANTGLVETITNAMSVHSIK 855
Query: 1233 ---TEWGLTGS-FKDKPIAEWLAKH------NPSELEYQRARDNFTASCAGYSVATYLLG 1282
T+ + + DK L H NP+ +Y+RA+DNF +S A YSV YLL
Sbjct: 856 KALTKKMIEDAELDDKGGIASLNDHFLRAFGNPNGFKYRRAQDNFASSLAAYSVICYLLQ 915
Query: 1283 ICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGE 1342
+ DRHN NIM+ GH+ HIDFG M N V + APF LT++ + ++ G E
Sbjct: 916 VKDRHNGNIMIDNEGHVSHIDFG------FMLSNSPGSVGFEAAPFKLTYEYIELLGGVE 969
Query: 1343 RPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
+ F+ FVEL +F +R + D I+ + + D+
Sbjct: 970 --GEAFKKFVELTKSSFKALRKYADQIVSMCEIMQKDN 1005
>UniRef50_Q76NU6 Cluster: Similar to Homo sapiens (Human).
Phosphatidylinositol 4-kinase 230; n=2; Dictyostelium
discoideum|Rep: Similar to Homo sapiens (Human).
Phosphatidylinositol 4-kinase 230 - Dictyostelium
discoideum (Slime mold)
Length = 2457
Score = 121 bits (292), Expect = 1e-25
Identities = 74/205 (36%), Positives = 113/205 (55%), Gaps = 10/205 (4%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK GDD+RQD L LQ+I I ++ GLDL + ++ + T GMIE+V T+
Sbjct: 2198 IFKSGDDIRQDMLALQIIDIFKRIFKYVGLDLYLFPYKVIATKPGCGMIELVPN--TMSR 2255
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
Q + G+ + I+++ N + + +Q AR NF S A YSV +Y+L I DRHN N
Sbjct: 2256 DQIGKKVNGNLYNYFISKY---GNKNSIGFQNARRNFIKSMAAYSVVSYILQIKDRHNAN 2312
Query: 1291 IMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQH 1350
I++ GH+ HIDFG F+ D G L+ + +PF + +M+ ++ GG+ ++F
Sbjct: 2313 ILVDEEGHIVHIDFG-FIFDISPGG---ELLTFEASPFKMNQEMIDIM-GGKPNAEQFVW 2367
Query: 1351 FVELCCMAFNIVRAHHDHILDLFAL 1375
F+E AF R H D I+ L L
Sbjct: 2368 FMEQSVRAFLAARQHMDSIITLVEL 2392
>UniRef50_Q4QAC9 Cluster: Phosphatidylinositol 3-kinase, putative;
n=3; Leishmania|Rep: Phosphatidylinositol 3-kinase,
putative - Leishmania major
Length = 1089
Score = 121 bits (291), Expect = 2e-25
Identities = 75/234 (32%), Positives = 125/234 (53%), Gaps = 24/234 (10%)
Query: 1164 DNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVT 1223
D + M+K DD+RQD L++Q+I++M+ L + G+ L + ++ + T ++G++EIV
Sbjct: 831 DTVPLAMMYKYNDDIRQDQLIVQLIRLMNDLLQQDGMQLYLTPYRVIATGPNEGLVEIVP 890
Query: 1224 EAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGI 1283
+ T ++Q + + ++L +N + ++A D +T S AGY V T++LGI
Sbjct: 891 QVTTFFSVQRD-----------VLKYLRVYNNTAELLRQAMDRYTRSFAGYCVITFVLGI 939
Query: 1284 CDRHNDNIMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGE 1342
DRH +NI++ G L HIDFG LG D + F P + +MV V+ GG
Sbjct: 940 GDRHLENILITQDGRLLHIDFGYVLGNDPKPF----------PPPMKINREMVEVL-GGP 988
Query: 1343 RPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGSERTVAGGRPQMSL 1396
+ T F F CC A+N +R H +L + L + G + T GG P+++L
Sbjct: 989 QST-GFTEFKLYCCSAYNTLRKHAPLLLHILLLGAHTEGMPQVTGEGGDPRVNL 1041
Score = 42.3 bits (95), Expect = 0.098
Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 904 VMWEKRQYLVQIPGALPLVLLAATNWYGDH---REQLIGLLRLWEKPSPLNAMHLLLPCF 960
++W+ R ++ + G L + +W H R L+ W +P+ + + L F
Sbjct: 386 LLWKYRHFICR-DGKYFLPFMRCVDWANTHSSERRAACALIHQWARPAFEDVLACLSFYF 444
Query: 961 PDVA-VRETAAKLLNEMSDDDLCRVLPQLTQALRHET 996
VA VR+ A +LL D LC++ QL QA+R+++
Sbjct: 445 DHVAPVRQYAVRLLRREGDGRLCQLAFQLVQAVRYDS 481
>UniRef50_Q17PY3 Cluster: Phosphatidylinositol 4-kinase; n=4;
Coelomata|Rep: Phosphatidylinositol 4-kinase - Aedes
aegypti (Yellowfever mosquito)
Length = 2069
Score = 121 bits (291), Expect = 2e-25
Identities = 78/208 (37%), Positives = 114/208 (54%), Gaps = 16/208 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD+RQD L LQVI I ++ + GL+L + ++ + T+ G+IE V A++
Sbjct: 1814 AIFKVGDDVRQDMLALQVISIFKNIFQQVGLELFLFPYRVVATAPGCGVIECVPNAKSRD 1873
Query: 1230 AI--QTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287
+ QT+ GL F + E + E+Q AR NF S A YSV YLL I DRH
Sbjct: 1874 QLGRQTDSGLYEYFLHQYGDE-------TSKEFQVARSNFVKSMAAYSVIGYLLQIKDRH 1926
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
N NIM+ GH+ HIDFG F+ ++ GN I P + D + ++ GG+
Sbjct: 1927 NGNIMIDKDGHIIHIDFG-FMFESSPGGN------IGFEPDLKLTDEMVMVMGGKMEAAP 1979
Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375
F+ F +LC +F +R + D I+ L +L
Sbjct: 1980 FKWFCDLCVQSFLAIRPYQDAIVTLVSL 2007
>UniRef50_Q9USR3 Cluster: Phosphatidylinositol kinase; n=1;
Schizosaccharomyces pombe|Rep: Phosphatidylinositol
kinase - Schizosaccharomyces pombe (Fission yeast)
Length = 1877
Score = 120 bits (290), Expect = 2e-25
Identities = 77/202 (38%), Positives = 108/202 (53%), Gaps = 16/202 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I + ++ GLD+ + ++ T+ G+I+++ +
Sbjct: 1621 AIFKVGDDCRQDVLTLQLIAMFKNIFNSVGLDVYLFPYRVTATNPGCGVIDVLPNCISRD 1680
Query: 1230 AIQTEW--GLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287
+ E GL F+ K E + +Q+AR NF S A YSV TYLL DRH
Sbjct: 1681 MLGREAVNGLYDYFRTKFGDE-------DSIAFQKARSNFVQSMAAYSVITYLLQFKDRH 1733
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
N NIM+ GH+ HIDFG F+ D G + + APF LT +M+ V+ GG +Q
Sbjct: 1734 NGNIMIDDQGHILHIDFG-FIFDIAPGG-----ITFESAPFKLTTEMIAVM-GGSNKSQP 1786
Query: 1348 FQHFVELCCMAFNIVRAHHDHI 1369
FQ F ELC AF R + +I
Sbjct: 1787 FQWFQELCVKAFLACRPYAHYI 1808
>UniRef50_O04269 Cluster: Phosphatidylinositol 3-kinase; n=2; cellular
organisms|Rep: Phosphatidylinositol 3-kinase -
Chlamydomonas reinhardtii
Length = 732
Score = 120 bits (289), Expect = 3e-25
Identities = 80/206 (38%), Positives = 108/206 (52%), Gaps = 18/206 (8%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
++K GDDLRQD VLQ+I +MD + + LDLRM ++ LPTS G++E V L A
Sbjct: 480 IYKKGDDLRQDHFVLQMIGLMDRMLKRENLDLRMTPYKVLPTSFDDGLVEFVPSVP-LSA 538
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
+ E F A+ P L + A + F SCAGY V TY+LG+ DRH DN
Sbjct: 539 VLAEHKTIHRFLALTQAD---AGGPFGLRAE-AVETFVRSCAGYCVMTYILGVGDRHLDN 594
Query: 1291 IMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQ 1349
+ML G LFHIDFG LG D + F P L +M+ + G + ++ ++
Sbjct: 595 LMLTHDGRLFHIDFGYILGADTKPF----------PPPMKLCKEMIEAMGG--QGSEYYK 642
Query: 1350 HFVELCCMAFNIVRAHHDHILDLFAL 1375
F C A+NI+R D IL LF L
Sbjct: 643 QFRMYACEAYNILRKRADLILSLFHL 668
Score = 46.4 bits (105), Expect = 0.006
Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 900 ECREVMWEKRQYLVQIPGALPLVLLAATNWY-GDHREQLIGLLRLWEKPSPLNAMHLLLP 958
E R ++W R L Q AL L +W +Q L+R W S +A+ LL P
Sbjct: 74 EERALLWRFRASLTQDTRALTK-FLQCVDWSDATEAKQAAELMRQWAPISAADALELLSP 132
Query: 959 CFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
F VR+ A + L + ++L L QL QALR+E
Sbjct: 133 DFRSEVVRQHAVQALQAVEVEELGAYLLQLVQALRYE 169
>UniRef50_A2EUN5 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Trichomonas vaginalis G3|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Trichomonas vaginalis G3
Length = 1411
Score = 120 bits (289), Expect = 3e-25
Identities = 78/231 (33%), Positives = 123/231 (53%), Gaps = 17/231 (7%)
Query: 1150 SSNTLPLKINFIGTD--NAVIP--AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMV 1205
S + +P+ +NF D N P +FK+ DD+R D L++Q+I + ++GLD+ +
Sbjct: 1130 SHSRVPILVNFEVEDKENKRFPYGCIFKIQDDVRTDCLMIQLIDKFGVICRESGLDIYVC 1189
Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNP-SELEYQRAR 1264
++ T +G+IE++ A++ I G+T +K + + + K P ++ A+
Sbjct: 1190 PYKVFSTGFDRGVIEVIQHAKSRHDI----GMT--YKSELLHYFTTKFGPIGTPKFNAAQ 1243
Query: 1265 DNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYID 1324
DNF S A YS+ YL + DRHN NIM+ GH+ HIDFG F+ D GN K +
Sbjct: 1244 DNFIKSLASYSLICYLFQVKDRHNANIMIDDEGHIIHIDFG-FIFDISPGGNIK----FE 1298
Query: 1325 RAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
RAPF LT + V V+ GG FQ FV L F V++ + I+++ L
Sbjct: 1299 RAPFKLTREYVNVL-GGSTDAVPFQRFVTLFMRCFLAVQSRYIEIINIVEL 1348
>UniRef50_A7P941 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 1946
Score = 120 bits (288), Expect = 4e-25
Identities = 89/263 (33%), Positives = 136/263 (51%), Gaps = 24/263 (9%)
Query: 1130 LPLALHKYVHDLDVKS-CTYFSSNTLPLKINFI-----GTDNAVIP--AMFKVGDDLRQD 1181
LP A K V + V S T S+ +P+ I F G N + P +FKVGDD RQD
Sbjct: 1639 LPTATTKLVKGIQVDSGITLQSAAKVPIMITFNVVDREGNHNDIKPQACIFKVGDDCRQD 1698
Query: 1182 ALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAI--QTEWGLTG 1239
L LQVI ++ ++ GL+L + + LPT +G+IE+V + + + T+ GL
Sbjct: 1699 VLALQVISLLRDIFEAVGLNLYVFPYGVLPTGPGRGIIEVVPNSRSRSQMGETTDGGLYE 1758
Query: 1240 SFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHL 1299
F+ ++ +PS ++ ARDNF S AGY+VA+ +L DRHN N++ G L
Sbjct: 1759 IFQQ----DFGPVGSPS---FENARDNFIISSAGYAVASLILQPKDRHNGNLLFDKEGRL 1811
Query: 1300 FHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVIN-GGERPTQRFQHFVELCCMA 1358
HIDFG F+ + GN + + A F L+H+M +++ G ++ + FV LC
Sbjct: 1812 VHIDFG-FILETSPGGNMR----FESAHFKLSHEMTQLLDPSGVMKSETWYKFVSLCVKG 1866
Query: 1359 FNIVRAHHDHILDLFALPSCDSG 1381
+ R + D I++ L DSG
Sbjct: 1867 YLAARRYMDGIVNT-VLMMVDSG 1888
>UniRef50_A7F5M2 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 1886
Score = 120 bits (288), Expect = 4e-25
Identities = 81/212 (38%), Positives = 115/212 (54%), Gaps = 13/212 (6%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I ++ GLD+ + ++ T+ G+I+++ + +
Sbjct: 1631 AIFKVGDDCRQDVLALQMIAAFRGIFNNVGLDVYVFPYRVTATAPGCGVIDVLPNSISRD 1690
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHND 1289
+ E + G F D I+++ N L +Q AR NF S A YSV ++LL DRHN
Sbjct: 1691 MLGRE-AVNGLF-DYFISKY---GNEDSLRFQEARANFVKSMAAYSVISFLLQFKDRHNG 1745
Query: 1290 NIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQ 1349
NIM+ +GH+ HIDFG F D G V +RAPF LT +MV V+ GG Q F+
Sbjct: 1746 NIMIDDAGHILHIDFG-FCFDIAPGG-----VKFERAPFKLTTEMVAVM-GGSTEHQAFK 1798
Query: 1350 HFVELCCMAFNIVRAHHDHILDLFALPSCDSG 1381
F ELC A+ R + + + L L DSG
Sbjct: 1799 WFEELCVKAYLASRPYTEKLSQLVML-MMDSG 1829
>UniRef50_Q01CW4 Cluster: Phosphatidylinositol 3-kinase; n=2; cellular
organisms|Rep: Phosphatidylinositol 3-kinase -
Ostreococcus tauri
Length = 845
Score = 119 bits (286), Expect = 7e-25
Identities = 84/239 (35%), Positives = 115/239 (48%), Gaps = 30/239 (12%)
Query: 1143 VKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDL 1202
+ + F S PLK+ F +FK GDDLRQD L +Q+I +MD L + LDL
Sbjct: 565 ISESSVFKSALSPLKLTFQTLTGDRATMIFKKGDDLRQDQLCVQMISLMDRLLKRENLDL 624
Query: 1203 RMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELE--- 1259
++ +++ L T + G+IE V ++ LT ++A HNP
Sbjct: 625 KLTSYRVLATGSDTGLIEFVKSQGVADILKEHEKLT---------TYIALHNPDPHGPNG 675
Query: 1260 -YQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFK 1318
+ NF SCAGYSV TYLLG+ DRH DN+ML + G LFHIDFG +G
Sbjct: 676 CTMTSMMNFVKSCAGYSVITYLLGVGDRHLDNLMLASDGRLFHIDFGFIMG--------- 726
Query: 1319 RLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHI--LDLFAL 1375
R I L +MV E + F F CC A+NI+R + L+LF+L
Sbjct: 727 RDPKISPPSMKLCKEMV------EAMGEYFSEFKTYCCEAYNILRKSESVVLLLNLFSL 779
Score = 52.8 bits (121), Expect = 7e-05
Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 2/114 (1%)
Query: 878 DGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQL 937
DG + +L +I+ + + E + ++W+ R + Q P AL L +W +
Sbjct: 274 DGSEKRRLATIIQLPPTRPLDMESQNLLWKFRFAMRQDPRALTK-FLKCVDWSDPAETKA 332
Query: 938 -IGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQ 990
+ L+R WE P A+ LL P F +V VR A +L + ++DL L QL Q
Sbjct: 333 SVQLMREWEPIGPAAALELLTPTFTNVDVRRYAVAILRQTDEEDLLMYLLQLVQ 386
>UniRef50_Q9TXI7 Cluster: Related to yeast vacuolar protein sorting
factor protein 34, isoform a; n=7; Caenorhabditis|Rep:
Related to yeast vacuolar protein sorting factor protein
34, isoform a - Caenorhabditis elegans
Length = 901
Score = 119 bits (286), Expect = 7e-25
Identities = 82/243 (33%), Positives = 134/243 (55%), Gaps = 27/243 (11%)
Query: 1145 SCTYFSSNTLPLKINFI-----GTDNAVIP----AMFKVGDDLRQDALVLQVIKIMDTLW 1195
+ ++F S +P KI+F G + IP +FK GDDLRQD L+ Q+++++D +
Sbjct: 610 TASFFKSEMMPAKISFKVLQPNGKADRNIPEEYTVIFKTGDDLRQDQLIQQMVRLIDIIL 669
Query: 1196 LKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNP 1255
K LDL++ + L T +G ++ + +++ LRAIQ ++ + K I E + + P
Sbjct: 670 KKGQLDLKLTPYLVLSTGVGQGFVQCI-KSKPLRAIQEQYK---AHKMDCIREAMKELRP 725
Query: 1256 SELEY---QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQ 1312
+ + DN+ S AGYSV Y+LG+ DRH DN++L +G LFH+DFG LG
Sbjct: 726 GDGPFGIEPNVIDNYVRSLAGYSVIMYILGLGDRHLDNLLLCENGKLFHVDFGFILGRDP 785
Query: 1313 MFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDL 1372
K + P LT +MV V+ G + +++F FV+ A+ I+R H + +L+L
Sbjct: 786 -----KPMP----PPMKLTSEMVQVMGGVK--SKQFLEFVQHVDSAYRILRRHSNVLLNL 834
Query: 1373 FAL 1375
F+L
Sbjct: 835 FSL 837
Score = 54.0 bits (124), Expect = 3e-05
Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 3/116 (2%)
Query: 882 QSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNW-YGDHREQLIGL 940
+ +L ++ + Q + E R+++W+ R YL Q P AL L + NW + + + L
Sbjct: 313 KDRLETIVNLPSSQVLTREQRDLVWKFRHYLRQFPKALN-KYLRSVNWVHPQEVKTALAL 371
Query: 941 LRLWEKPSPLNAMHLLLPCFPDVAVRE-TAAKLLNEMSDDDLCRVLPQLTQALRHE 995
+ WE +A+ LL F AVR + ++LL S + + LPQL QAL++E
Sbjct: 372 MNDWELIEAEDALELLSSAFTHPAVRAYSVSRLLEAASPEQVLLYLPQLVQALKYE 427
>UniRef50_A4QVB3 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1899
Score = 119 bits (286), Expect = 7e-25
Identities = 73/207 (35%), Positives = 115/207 (55%), Gaps = 14/207 (6%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I ++ GLD+ + ++ T+ G+I+++ + +
Sbjct: 1644 AIFKVGDDCRQDVLALQMIAAFRGIFESVGLDVYVFPYRVTATAPGCGVIDVLPNSISRD 1703
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKH-NPSELEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
+ E + G ++ + +K+ N L +Q+AR+NF S A YS+ ++LL DRHN
Sbjct: 1704 MLGRE-AVNGLYE-----YFTSKYGNEDSLRFQQARNNFVKSMAAYSIISFLLQFKDRHN 1757
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
NIM+ +GH+ HIDFG F D G + +RAPF LT +M+ V+ GG +Q F
Sbjct: 1758 GNIMIDDAGHILHIDFG-FCFDIAPGG-----IKFERAPFKLTSEMMAVM-GGSMDSQAF 1810
Query: 1349 QHFVELCCMAFNIVRAHHDHILDLFAL 1375
+ F ELC +F R + D + + L
Sbjct: 1811 KQFEELCVKSFLASRPYADKLSQIVLL 1837
>UniRef50_Q752A9 Cluster: AFR666Cp; n=1; Eremothecium gossypii|Rep:
AFR666Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 997
Score = 117 bits (281), Expect = 3e-24
Identities = 74/210 (35%), Positives = 111/210 (52%), Gaps = 18/210 (8%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDLRQ+A Q+I+ M +W K +D+ + + L TS + G++E +T A ++ +I+
Sbjct: 727 KSGDDLRQEAFACQLIQAMANIWNKEKVDVWVKKMKILITSANTGLVETITNAISVHSIK 786
Query: 1233 ---TEWGLT-GSFKDKPIAEWLAKH------NPSELEYQRARDNFTASCAGYSVATYLLG 1282
T+ + G +K L H P+ Y+RA+DNF +S A YS+ Y+L
Sbjct: 787 KSLTKQMIEEGELNEKGTIATLCDHFSRSFGEPNSFRYKRAQDNFASSLAAYSLICYILQ 846
Query: 1283 ICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGE 1342
I DRHN NIM+ GHL HIDFG M N V + APF LT + V V+ G E
Sbjct: 847 IKDRHNGNIMIDNEGHLVHIDFG------FMLSNSPGSVGFEAAPFKLTQEYVDVLGGIE 900
Query: 1343 RPTQRFQHFVELCCMAFNIVRAHHDHILDL 1372
+ ++ F+ + AF +R H D + +
Sbjct: 901 --GEPYKKFIRVVKEAFRALRKHADMFVSM 928
>UniRef50_Q4QSD0 Cluster: PIKa; n=1; Candida parapsilosis|Rep: PIKa -
Candida parapsilosis (Yeast)
Length = 937
Score = 117 bits (281), Expect = 3e-24
Identities = 72/217 (33%), Positives = 118/217 (54%), Gaps = 16/217 (7%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDL Q+A Q+I ++ +W K G+ + L TS + G++E +T A ++ +I+
Sbjct: 667 KNGDDLPQEAFACQLITMISNIWKKHGISFWTKRMKILITSANAGLVETITNAMSIHSIK 726
Query: 1233 ---TEWGLTGSFKDK----PIAEWLAK--HNPSELEYQRARDNFTASCAGYSVATYLLGI 1283
TE + + + ++ + N S +Y++A++NF S A YS+ Y+L I
Sbjct: 727 KSFTELSIASGSNTRGRIFTLKDYFERLYGNESSRKYRQAQENFARSLASYSIICYVLQI 786
Query: 1284 CDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER 1343
DRHN NIML GH+ HIDFG LG++ G+ + + APF LT + V ++ G E
Sbjct: 787 KDRHNGNIMLDHEGHIIHIDFGFLLGNSP--GS---NIGFEAAPFKLTTEYVDILGGTE- 840
Query: 1344 PTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
++ ++ FVE+C F ++R D I+ + L DS
Sbjct: 841 -SEFYKLFVEVCQDCFKVLRKESDQIVSIVELMQKDS 876
>UniRef50_Q2PFD9 Cluster: Phosphatidylinositol 4-kinase; n=1; Pichia
pastoris|Rep: Phosphatidylinositol 4-kinase - Pichia
pastoris (Yeast)
Length = 1015
Score = 116 bits (280), Expect = 4e-24
Identities = 76/217 (35%), Positives = 117/217 (53%), Gaps = 17/217 (7%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDL Q+A Q+I+ M T+W G+++ + + L TSNS G++E +T+A ++ +I+
Sbjct: 746 KTGDDLTQEAFACQLIQSMATVWHNHGVNIWVKRMRILVTSNSTGLVETITDAVSIHSIK 805
Query: 1233 ---TEWGLTGSFKDKPIAEWLAKH------NPSELEYQRARDNFTASCAGYSVATYLLGI 1283
TE+ + + + L H +P+ Y++A++NF S A YSV Y+L I
Sbjct: 806 KSLTEYLIENNEDHRGAIATLLDHFRMTFGDPNSARYRKAQNNFAISLAAYSVICYILQI 865
Query: 1284 CDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER 1343
DRHN NIML GH+ HIDFG FL N V + APF LT + V V+ G +
Sbjct: 866 KDRHNGNIMLDNEGHIIHIDFG-FL-----LSNSPGSVGFEAAPFKLTLEYVDVLGGLD- 918
Query: 1344 PTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
+ FQ F + AF +R + + ++ + L DS
Sbjct: 919 -GEYFQVFKQSTKEAFKSLRRNAESLITMVELMQRDS 954
>UniRef50_Q9Y8E4 Cluster: Phosphatidylinositol 3-kinase Pdd1p; n=1;
Pichia angusta|Rep: Phosphatidylinositol 3-kinase Pdd1p -
Pichia angusta (Yeast) (Hansenula polymorpha)
Length = 1016
Score = 116 bits (279), Expect = 5e-24
Identities = 75/254 (29%), Positives = 122/254 (48%), Gaps = 26/254 (10%)
Query: 1127 PTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQ 1186
P LPL +V + + F S+ PLKI F + P M+K+GDDLRQD V+Q
Sbjct: 709 PVQLPLDPSVHVTGTIPEESSVFKSSLNPLKIVFKTIEGPPYPIMYKIGDDLRQDQFVIQ 768
Query: 1187 VIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPI 1246
++ +++ + L LD+++ ++ + + +G+I+ + + +Q K I
Sbjct: 769 IMTLVERILLNENLDMKLKPYKIMALGSVEGLIQFIPNSSLSSILQ---------KHLTI 819
Query: 1247 AEWLAKHNPSELE----YQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHI 1302
+L +NP DN+ SCAGY V TY+LG+ DRH +N++L T G+ FH
Sbjct: 820 LTYLQTYNPDPEAPLGVKSEVMDNYVRSCAGYCVLTYILGVGDRHLENLLLTTDGYFFHA 879
Query: 1303 DFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNI 1361
DFG LG D + F +L P + M G + +Q F C + +
Sbjct: 880 DFGYILGQDPKPFPPLMKL------PIQIIEGM------GGLNNENYQKFCNYCFITYIT 927
Query: 1362 VRAHHDHILDLFAL 1375
+R + IL++F L
Sbjct: 928 LRKNASLILNIFQL 941
>UniRef50_Q0UWD6 Cluster: Putative uncharacterized protein; n=5;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 1957
Score = 116 bits (279), Expect = 5e-24
Identities = 75/215 (34%), Positives = 115/215 (53%), Gaps = 15/215 (6%)
Query: 1168 IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAET 1227
+ A+FKVGDD RQD L LQ+I ++ GLD+ + ++ T+ G+I+++ + +
Sbjct: 1700 LSAIFKVGDDCRQDVLALQMIAAFRGIFNTVGLDVWVFPYRVTATAPGCGVIDVLPNSIS 1759
Query: 1228 LRAIQTEWGLTGSFKDKPIAEWLAKH-NPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286
+ E ++ A +++++ N + YQ AR NF S A YSV ++LL DR
Sbjct: 1760 RDMLGRE------AVNRLDAYFISRYGNEDSIRYQEARSNFVKSMAAYSVISFLLQFKDR 1813
Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346
HN NIM+ GH+ HIDFG F D G + +RAPF LT +M+ V+ GG Q
Sbjct: 1814 HNGNIMIDDMGHIIHIDFG-FCFDIAPGG-----IKFERAPFKLTAEMIAVM-GGSTTAQ 1866
Query: 1347 RFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSG 1381
++ F EL AF R H +H+ + + DSG
Sbjct: 1867 PYRWFEELTVKAFLAARQHANHLSHIVEV-MLDSG 1900
>UniRef50_Q80Y45 Cluster: Pik4ca protein; n=3; Euteleostomi|Rep:
Pik4ca protein - Mus musculus (Mouse)
Length = 516
Score = 116 bits (278), Expect = 7e-24
Identities = 73/208 (35%), Positives = 112/208 (53%), Gaps = 16/208 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I + ++ GLDL + ++ + T+ G+IE + + +
Sbjct: 261 AIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 320
Query: 1230 AI--QTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287
+ QT++G+ F + E S L +Q+AR NF S A YS+ +LL I DRH
Sbjct: 321 QLGRQTDFGMYDYFTRQYGDE-------STLAFQQARYNFIRSMAAYSLLLFLLQIKDRH 373
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
N NIML GH+ HIDFG F+ ++ GN + P + D + +I GG+
Sbjct: 374 NGNIMLDKKGHIIHIDFG-FMFESSPGGN------LGWEPDIKLTDEMVMIMGGKMEATP 426
Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375
F+ F+E+C + VR + D ++ L L
Sbjct: 427 FKWFMEMCVRGYLAVRPYMDAVVSLVTL 454
>UniRef50_P42356 Cluster: Phosphatidylinositol 4-kinase alpha; n=31;
Eumetazoa|Rep: Phosphatidylinositol 4-kinase alpha - Homo
sapiens (Human)
Length = 2044
Score = 116 bits (278), Expect = 7e-24
Identities = 73/208 (35%), Positives = 112/208 (53%), Gaps = 16/208 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I + ++ GLDL + ++ + T+ G+IE + + +
Sbjct: 1789 AIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 1848
Query: 1230 AI--QTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287
+ QT++G+ F + E S L +Q+AR NF S A YS+ +LL I DRH
Sbjct: 1849 QLGRQTDFGMYDYFTRQYGDE-------STLAFQQARYNFIRSMAAYSLLLFLLQIKDRH 1901
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
N NIML GH+ HIDFG F+ ++ GN + P + D + +I GG+
Sbjct: 1902 NGNIMLDKKGHIIHIDFG-FMFESSPGGN------LGWEPDIKLTDEMVMIMGGKMEATP 1954
Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375
F+ F+E+C + VR + D ++ L L
Sbjct: 1955 FKWFMEMCVRGYLAVRPYMDAVVSLVTL 1982
>UniRef50_Q9ZPE1 Cluster: Phosphatidylinositol 4-kinase; n=7;
Viridiplantae|Rep: Phosphatidylinositol 4-kinase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1121
Score = 115 bits (277), Expect = 9e-24
Identities = 76/232 (32%), Positives = 126/232 (54%), Gaps = 18/232 (7%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDD RQ+ L +Q+I ++ +AGL L + ++ L TS+ +IE + + ++ +I+
Sbjct: 864 KSGDDCRQEHLAVQLISHFYDIFQEAGLPLWLRPYEVLVTSSYTALIETIPDTASIHSIK 923
Query: 1233 TEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIM 1292
+ + S +D +A++ +++PS ++ A+ NF S AGYS+ YLL + DRHN N++
Sbjct: 924 SRYPNITSLRDFFVAKY-KENSPS---FKLAQRNFVESMAGYSLVCYLLQVKDRHNGNLL 979
Query: 1293 LKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER--PTQRFQH 1350
L GH+ HIDFG L ++ NF + APF LT +++ V++ P++ F +
Sbjct: 980 LDEEGHIIHIDFGFMLSNSPGGVNF------ESAPFKLTRELLEVMDSDADGVPSEFFDY 1033
Query: 1351 FVELCCMAFNIVRAHHDHILDLFALPSCDSG-----GSERTVAGGRPQMSLS 1397
F LC F R H + I+ L + DSG G RT+ R + LS
Sbjct: 1034 FKVLCIQGFLTCRKHAERIILLVEMLQ-DSGFPCFKGGPRTIQNLRKRFHLS 1084
>UniRef50_Q8LPD1 Cluster: Phophatdylinositol 4-kinase; n=9;
Magnoliophyta|Rep: Phophatdylinositol 4-kinase - Oryza
sativa (Rice)
Length = 278
Score = 114 bits (274), Expect = 2e-23
Identities = 72/232 (31%), Positives = 123/232 (53%), Gaps = 18/232 (7%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDD RQ+ L +Q++ + ++ +AGL L + ++ + TS +IE + + ++ +I+
Sbjct: 21 KSGDDCRQEHLAVQLVAHLYDIYQEAGLPLWLRPYEVIVTSAYTALIETIPDTASIHSIK 80
Query: 1233 TEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIM 1292
+ + S +D ++AK+ + ++ A+ NF S AGYS+ YLL + DRHN N++
Sbjct: 81 SRFPDITSLRDY----YVAKYEENSPNFKLAQRNFVESMAGYSILCYLLQVKDRHNGNLL 136
Query: 1293 LKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER--PTQRFQH 1350
+ GH+ HIDFG L ++ NF + APF LT +++ V++ P++ F +
Sbjct: 137 IDEEGHIIHIDFGFMLSNSPGGVNF------ESAPFKLTRELLEVMDSDAEGTPSEFFDY 190
Query: 1351 FVELCCMAFNIVRAHHDHILDLFALPSCDSG-----GSERTVAGGRPQMSLS 1397
F LC F R H + I+ L + DSG G RT+ R + LS
Sbjct: 191 FKVLCIQGFLTCRKHAERIILLVEMLQ-DSGFPCFKGGPRTIQNLRKRFHLS 241
>UniRef50_A3LZ98 Cluster: Phosphatidylinositol 4-kinase PIK1alpha;
n=1; Pichia stipitis|Rep: Phosphatidylinositol 4-kinase
PIK1alpha - Pichia stipitis (Yeast)
Length = 971
Score = 114 bits (274), Expect = 2e-23
Identities = 75/218 (34%), Positives = 114/218 (52%), Gaps = 18/218 (8%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGL-DLRMVTFQALPTSNSKGMIEIVTEAETLRAI 1231
K GDDL Q+A Q+I ++ ++W + G+ D + L TS + G++E + A ++ +I
Sbjct: 701 KNGDDLPQEAFACQLISLITSIWKRQGVKDAWTKRMKILITSANTGLVETINNAMSIHSI 760
Query: 1232 Q---TEWGLTGSFKDKPIAEWLAKH------NPSELEYQRARDNFTASCAGYSVATYLLG 1282
+ TE + K L + +P+ +Y+RA++NF S A YS+ Y+L
Sbjct: 761 KKSMTEISINDGENTKGRIFTLQDYFENMFGSPTSQKYKRAQNNFARSLASYSIICYVLQ 820
Query: 1283 ICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGE 1342
I DRHN NIML GH+ HIDFG FL N V + APF LT + V ++ G E
Sbjct: 821 IKDRHNGNIMLDNDGHIIHIDFG-FL-----LSNSPGSVGFEAAPFKLTSEYVNLLGGNE 874
Query: 1343 RPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
+ + FV++C FN +R H I++L L DS
Sbjct: 875 --SAPYLSFVDMCKKCFNALRKEHRQIVNLVELMQKDS 910
>UniRef50_UPI000049A205 Cluster: phosphatidylinositol 4-kinase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: phosphatidylinositol
4-kinase - Entamoeba histolytica HM-1:IMSS
Length = 1656
Score = 113 bits (273), Expect = 3e-23
Identities = 74/252 (29%), Positives = 132/252 (52%), Gaps = 17/252 (6%)
Query: 1130 LPLALHKYVHDLDVKSCTYF-SSNTLPLKINFIGTDNAV-----IPAMFKVGDDLRQDAL 1183
+P + V D+ K C S+ +P+ +N D +P +FK GDD+R D L
Sbjct: 1351 VPTNPNAMVVDVSNKGCACLRSAAKVPILVNMTVKDRFTGEVTPLPVIFKAGDDIRSDML 1410
Query: 1184 VLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKD 1243
+Q+I++ D + AGLD+ + + + T G+IE+V + + + ++ G+ +
Sbjct: 1411 AVQMIELFDRINKHAGLDIYLCPYHIIATGPDCGIIEVVRNSMSRDQMGEKYD--GNMYN 1468
Query: 1244 KPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHID 1303
+ ++ + E+ AR NF S + Y++ +Y+L I DRHN NI++ GHL HID
Sbjct: 1469 YFLTKYGGRKTE---EFFAARANFIRSMSAYAIVSYILQIKDRHNGNILIDEDGHLIHID 1525
Query: 1304 FGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVR 1363
FG F+ D G+ + I+++PF LT +M+ ++ GG ++F F+E +F +R
Sbjct: 1526 FG-FMFDRSPGGD----MGIEKSPFKLTDEMISIM-GGSPSAEQFIWFMEQGVKSFLAIR 1579
Query: 1364 AHHDHILDLFAL 1375
++ I+ L L
Sbjct: 1580 QYYPSIVTLIEL 1591
>UniRef50_Q4P4N2 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1302
Score = 113 bits (273), Expect = 3e-23
Identities = 76/222 (34%), Positives = 117/222 (52%), Gaps = 16/222 (7%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
V + K G DLRQ+ L +Q+I +W + G + F+ L TS + G++E +T+A
Sbjct: 1030 VFSVIVKTGADLRQEQLAVQLINEFGRIWHETGSRCWVRYFRILVTSENSGLMETITDAV 1089
Query: 1227 TLRAIQTEWGLTGSFKDKPIA-------EWLAKHNPSELE-YQRARDNFTASCAGYSVAT 1278
++ +I+ E S +DK + +LA + PS + + ARD F S AGYS+ +
Sbjct: 1090 SVHSIKKEAYSRMSQQDKAASAGFSLYDHFLAAYGPSTSKSFNAARDRFIESLAGYSIIS 1149
Query: 1279 YLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI 1338
YLL I DRHN NI++ G L HIDFG LG + G V + APF + + + ++
Sbjct: 1150 YLLQIKDRHNGNILVDNHGRLIHIDFGFMLGISP--GG----VGFEAAPFKMPQEYIDIL 1203
Query: 1339 NGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
G E + +F+ F +L F VR H + I+ L L + DS
Sbjct: 1204 GGLE--SAKFEEFKQLMRQGFRDVRKHAERIIMLVELMAKDS 1243
>UniRef50_O81129 Cluster: Phosphatidylinositol 4-kinase; n=6;
Eukaryota|Rep: Phosphatidylinositol 4-kinase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 2028
Score = 113 bits (272), Expect = 4e-23
Identities = 85/253 (33%), Positives = 128/253 (50%), Gaps = 25/253 (9%)
Query: 1130 LPLALHKYVHDLDVKS-CTYFSSNTLPLKINFI-----GTDNAVIP--AMFKVGDDLRQD 1181
LP A +K V + V S S+ +P+ I F G + V P +FKVGDD RQD
Sbjct: 1721 LPTAPNKLVRGIRVDSGIPLQSAAKVPIMITFNVIDRDGDHSDVKPQACIFKVGDDCRQD 1780
Query: 1182 ALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIV--TEAETLRAIQTEWGLTG 1239
L LQVI ++ ++ AGL+L + + LPT +G+IE+V T + + T+ GL
Sbjct: 1781 VLALQVISLLRDIFQAAGLNLYLFPYGVLPTGAERGIIEVVPNTRSRSQMGETTDGGLYE 1840
Query: 1240 SFKDKPIAEWLAKHNP-SELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGH 1298
F+ + P ++ AR+NF S AGY+VA+ LL DRHN N++ G
Sbjct: 1841 IFQQ--------DYGPVGSTTFETARENFLISSAGYAVASLLLQPKDRHNGNLLFDDVGR 1892
Query: 1299 LFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVIN-GGERPTQRFQHFVELCCM 1357
L HIDFG F+ + GN + + A F L+H+M +++ G ++ + FV LC
Sbjct: 1893 LVHIDFG-FILETSPGGNMR----FESAHFKLSHEMTQLLDPSGVMKSKTWHQFVSLCVK 1947
Query: 1358 AFNIVRAHHDHIL 1370
+ R D I+
Sbjct: 1948 GYLAARRQMDGII 1960
>UniRef50_Q4WG47 Cluster: Phosphatidylinositol 4-kinase (STT4),
putative; n=1; Aspergillus fumigatus|Rep:
Phosphatidylinositol 4-kinase (STT4), putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 1804
Score = 112 bits (270), Expect = 6e-23
Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 11/175 (6%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I +++ AGLD+ + ++ T+ G+I+++ + +
Sbjct: 1524 AIFKVGDDCRQDMLALQMIAAFRSIFASAGLDVWVFPYRVTSTAPGCGVIDVLPNSISRD 1583
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHND 1289
+ E + G + D I+++ +H+ + +Q AR NF S A YSV +YLL DRHN
Sbjct: 1584 MLGRE-AVNGLY-DYFISKYGGEHS---MRFQEARTNFVKSMAAYSVISYLLQFKDRHNG 1638
Query: 1290 NIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERP 1344
NIM+ +GH+ HIDFG F D G V +RAPF LT +MV V++G P
Sbjct: 1639 NIMIDDAGHIIHIDFG-FCFDIAPGG-----VRFERAPFKLTSEMVAVMSGTSHP 1687
>UniRef50_A4R924 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 927
Score = 111 bits (268), Expect = 1e-22
Identities = 70/223 (31%), Positives = 114/223 (51%), Gaps = 17/223 (7%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ + K G DLRQ+A Q+I + +W+ AG+ + + + L T S G+IE +T
Sbjct: 653 LVSVIVKTGADLRQEAFACQLINVCHRIWVNAGVPVWVKLMRILVTGESSGLIETITNGV 712
Query: 1227 TLRAIQTEWGLT----GSFKDKPIA----EWLAKHNPSELEYQRAR-DNFTASCAGYSVA 1277
+L +I+ L+ G + IA ++ P + E +A D F S A YS+
Sbjct: 713 SLHSIKRSLTLSTIESGQNPRRRIATLKDHFVKVFGPVDSEPHKAGVDAFKRSLAAYSMI 772
Query: 1278 TYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYV 1337
+Y+L + DRHN N+++ GH+ HIDFG M N V + +PF TH+ + V
Sbjct: 773 SYILQLKDRHNGNVLVDNEGHIIHIDFG------FMLSNSPGAVGFEASPFKFTHEYLEV 826
Query: 1338 INGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
+ G P F+ F +LC AF +R D+I+DL ++ +S
Sbjct: 827 LGGIGSP--EFEDFKKLCKQAFQALRREADNIIDLVSMMGRES 867
>UniRef50_P54677 Cluster: Phosphatidylinositol 4-kinase; n=2;
Dictyostelium discoideum|Rep: Phosphatidylinositol
4-kinase - Dictyostelium discoideum (Slime mold)
Length = 1093
Score = 111 bits (266), Expect = 2e-22
Identities = 73/218 (33%), Positives = 110/218 (50%), Gaps = 17/218 (7%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDD RQ+ + +Q+I D +W + L L + + L TS+ G+IE + + +L ++
Sbjct: 837 KTGDDCRQEQMAVQLISKFDEIWKETRLPLYLRPYSILVTSSGGGIIETIPDTMSLHNLK 896
Query: 1233 TEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIM 1292
T F +PS L ++ A+ NF S A YS+ TY+L I DRHN NI+
Sbjct: 897 KS---TPGFTTLLNYFKSTYGDPSGLRFRTAQSNFIESMAAYSIVTYILQIKDRHNGNIL 953
Query: 1293 LKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFV 1352
+ GH+ HIDFG L ++ GN + + APF LT ++V V+ G + + +FQ+F
Sbjct: 954 IDKEGHIVHIDFGFILSNSP--GN----ISFESAPFKLTQELVDVMGGIQ--SGQFQYFK 1005
Query: 1353 ELCCMAFNIVRAHHDHILDLFAL------PSCDSGGSE 1384
LC R D I+ L + SC GG E
Sbjct: 1006 VLCVRGLIEARKQVDKIISLIEIMMSGPKMSCFVGGKE 1043
>UniRef50_A0CXG8 Cluster: Chromosome undetermined scaffold_30, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_30, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 713
Score = 110 bits (264), Expect = 3e-22
Identities = 67/213 (31%), Positives = 118/213 (55%), Gaps = 17/213 (7%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ + K GD+L+Q+ +Q++ +D +++ L +R+ ++ + + G+IE+V +A
Sbjct: 452 LVHLIVKSGDNLKQEQFAMQLLSTIDQIFIIEDLPMRLSIYEVISLGPNYGLIEMVKDAI 511
Query: 1227 TLRAIQTE-WGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICD 1285
T+ +++ + W + + ++++ HN S+ R R NF S GYS+A Y+L + D
Sbjct: 512 TIDSLKRQLWN-----RQQTLSQFF-DHNFSD----RHRTNFMQSLVGYSLACYILQLKD 561
Query: 1286 RHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPT 1345
RHN NI+LK GHL HIDFG FLG+A K + ++ PF L + + ++ G + +
Sbjct: 562 RHNGNILLKRDGHLAHIDFGFFLGNAP----GKGIEIENKVPFKLLSEQIEILGGVQ--S 615
Query: 1346 QRFQHFVELCCMAFNIVRAHHDHILDLFALPSC 1378
F+ F EL F +R H D IL L + C
Sbjct: 616 DLFKKFRELFYKGFMALRKHSDRILLLVKMMYC 648
>UniRef50_Q4PHG0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 975
Score = 110 bits (264), Expect = 3e-22
Identities = 72/208 (34%), Positives = 104/208 (50%), Gaps = 19/208 (9%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK GDDLRQD LV+Q+ +MD L LDL+M ++ L T + GM++ V
Sbjct: 721 IFKNGDDLRQDQLVIQLFSLMDRLLRNENLDLKMTPYRVLATGSVDGMVQFVDSLSIAAI 780
Query: 1231 IQTEWGLTGSFKDKPIAE--WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
+ G +F A+ L+ + + + D F SCAGY V TYLLG+ DRH
Sbjct: 781 LSAHQGSLLNFLRAHHAQPSSLSTYGVDAVVF----DTFIRSCAGYCVVTYLLGVGDRHL 836
Query: 1289 DNIMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
DN++L + GH FH+DFG LG D + F P + +MV + G +
Sbjct: 837 DNLLLSSDGHFFHVDFGYILGRDPKPF----------PPPVKVCKEMVDAMGG--TSSAH 884
Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+ F C AF +R + + IL+L AL
Sbjct: 885 YARFKAFCYTAFTNLRKNANLILNLVAL 912
Score = 50.4 bits (115), Expect = 4e-04
Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Query: 882 QSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNW--YGDHREQLIG 939
+ +L ++ + + T + +W R YL + P L L + W G+ ++
Sbjct: 350 RDELNEILSYPPTRELTTAEMDRVWSFRFYLTRDPKGLTKFLKSVV-WTDQGEAKQATEV 408
Query: 940 LLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHE 995
LL +W +P +A+ LL P F D VR A + L D++L L QL QAL+ +
Sbjct: 409 LLPMWNEPGLDDALELLGPTFKDARVRSYAVRQLERAEDEELILYLLQLVQALKFD 464
>UniRef50_Q4P1B0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 2187
Score = 109 bits (261), Expect = 8e-22
Identities = 74/203 (36%), Positives = 108/203 (53%), Gaps = 15/203 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQVI + ++ G+DL + ++ T G+I++V A +
Sbjct: 1930 AIFKVGDDCRQDVLALQVIAMFKNIYTTVGIDLYLNPYRVTATGPGCGVIDVVPNATS-- 1987
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKH-NPSELEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
+ E G + + ++ K+ NP + +QRAR NF S A YSV ++L I DRHN
Sbjct: 1988 --RDEMGRAKI--NHLLTFFIGKYGNPDTIAFQRARINFIQSMAAYSVVCHILQIRDRHN 2043
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
N+M+ GHL HIDFG FL D G + + F L+H+M+ V+ G +Q F
Sbjct: 2044 GNMMIDGDGHLVHIDFG-FLFDIGPGG-----MRFEPYSFKLSHEMIDVMGG--PASQGF 2095
Query: 1349 QHFVELCCMAFNIVRAHHDHILD 1371
+ F EL AF R ++D
Sbjct: 2096 RMFEELVVKAFLACRPFCAEMVD 2118
>UniRef50_A5E2B6 Cluster: Phosphatidylinositol 4-kinase PIK1a; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep:
Phosphatidylinositol 4-kinase PIK1a - Lodderomyces
elongisporus (Yeast) (Saccharomyces elongisporus)
Length = 1017
Score = 109 bits (261), Expect = 8e-22
Identities = 71/217 (32%), Positives = 113/217 (52%), Gaps = 16/217 (7%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDL Q+A Q+I ++ +W K G+ + L TS + G++E +T + ++ +I+
Sbjct: 747 KNGDDLPQEAFACQLIILISNIWKKYGIHFWTKKMKILITSANAGLVETITNSMSIHSIK 806
Query: 1233 ---TEWGLTGSFKDK----PIAEWLAK--HNPSELEYQRARDNFTASCAGYSVATYLLGI 1283
TE + K + ++ K PS Y+RA+ NF S A YSV Y+L I
Sbjct: 807 KSLTELSIASGENSKGRIFTLRDYFEKLFGPPSSRAYRRAQGNFATSLASYSVICYVLQI 866
Query: 1284 CDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER 1343
DRHN NIM+ GH+ HIDFG LG++ G+ + + APF LT + + ++ G E
Sbjct: 867 KDRHNGNIMIDHEGHIIHIDFGFLLGNSP--GS---NIGFEAAPFKLTTEYIDLLGGME- 920
Query: 1344 PTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
++ +Q FV + F ++R I+ + L DS
Sbjct: 921 -SEHYQTFVSVFKDCFRVLRKEWTQIVSIVELMQKDS 956
>UniRef50_A2FAC3 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=6; Trichomonas vaginalis G3|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Trichomonas vaginalis G3
Length = 817
Score = 108 bits (260), Expect = 1e-21
Identities = 79/249 (31%), Positives = 115/249 (46%), Gaps = 24/249 (9%)
Query: 1127 PTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQ 1186
P LPL V+ +D F S P I F D +FK+GDD+RQD L+LQ
Sbjct: 521 PVRLPLDPEVVVNGVDPDDVKVFQSKLRPACICFKRADGGSYRVIFKIGDDMRQDQLILQ 580
Query: 1187 VIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPI 1246
+ +MD ++ +A + L + ++ L S + G + + ++ + I E +K I
Sbjct: 581 LFSVMDNIFKRASMQLNITAYKTLAFSPTFGCCQFIDNSKAILNIANE--------EKSI 632
Query: 1247 AEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGK 1306
++L N + FT S A YSV TY+L I DRH++NI++ GHL HID+G
Sbjct: 633 KKYLMADNK---PIGPKIELFTESLAAYSVMTYVLKIGDRHDNNILVTRDGHLLHIDYGF 689
Query: 1307 FLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHH 1366
LGD K P L+ +MV I+ P Q + C AFN +R
Sbjct: 690 ILGDVT-----KPFT----PPLKLSREMVDTID----PENGLQKICDWACPAFNSLRKRA 736
Query: 1367 DHILDLFAL 1375
IL L L
Sbjct: 737 RLILVLIEL 745
>UniRef50_A2EAP0 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Trichomonas vaginalis G3|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Trichomonas vaginalis G3
Length = 734
Score = 108 bits (260), Expect = 1e-21
Identities = 64/184 (34%), Positives = 97/184 (52%), Gaps = 12/184 (6%)
Query: 1126 QPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVL 1185
+P LP+ VH + +++ F S+ P+K +F+ V A+ K GDD+RQDAL L
Sbjct: 448 KPFRLPIMPSFIVHSISLENIIVFGSSLQPVKFDFLNDKKQVYSAILKYGDDMRQDALAL 507
Query: 1186 QVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKP 1245
IK +D GLDL M ++ LP S GM+E + A+ + + + +
Sbjct: 508 NTIKFIDDHLKGYGLDLCMSPYKVLPISKVFGMMEFIVGAKAVSKVLEQ-------NNDS 560
Query: 1246 IAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFG 1305
I+E+ K SE + R R F S A YSV +Y+LG+ DRH DN+++ G+ H+DFG
Sbjct: 561 ISEFWDK---SEGDMPRQR--FIKSSAAYSVVSYVLGVGDRHLDNLLVSKKGNFLHVDFG 615
Query: 1306 KFLG 1309
G
Sbjct: 616 YMFG 619
>UniRef50_Q9W0R8 Cluster: CG7004-PA, isoform A; n=5; Diptera|Rep:
CG7004-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 1674
Score = 107 bits (258), Expect = 2e-21
Identities = 65/205 (31%), Positives = 112/205 (54%), Gaps = 13/205 (6%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ A+ K GDDLRQ+ + Q++++ +W + +DL + ++ + SN G+IE +
Sbjct: 1414 LLSAIVKCGDDLRQELMATQLLQMFKIIWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTV 1473
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286
+L I+ S K+ I E+ +PS ++RA+ NF SCA Y + +YLL + DR
Sbjct: 1474 SLHQIKKN--SNKSLKEYFIDEY---GSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDR 1528
Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346
HN NI+ + GH+ HIDFG L + K L + +++PF LT + V V+ G ++
Sbjct: 1529 HNGNILFHSDGHIIHIDFGFILSISP-----KNLGF-EQSPFKLTPEFVEVMGG--TSSE 1580
Query: 1347 RFQHFVELCCMAFNIVRAHHDHILD 1371
++ F +L + R H D I++
Sbjct: 1581 HWREFNKLLLVGMMSARKHMDRIIN 1605
>UniRef50_Q22UI8 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 2284
Score = 107 bits (256), Expect = 3e-21
Identities = 72/215 (33%), Positives = 119/215 (55%), Gaps = 20/215 (9%)
Query: 1168 IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALP--TSNSK---GMIEIV 1222
+ +FKV DD+RQD L LQ+I + ++ KA L+L + ++ + T N+ G+IE+V
Sbjct: 2021 VSCIFKVFDDVRQDQLALQIITLFQGIFQKANLELYVFPYKTISNRTGNNLDIGGIIEVV 2080
Query: 1223 TEAETLRAIQTEWGLTG--SFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYL 1280
+ + + + G T S D I ++ + + + +Q AR+NF S A YSV +Y+
Sbjct: 2081 KNSIS----RDQLGKTNQCSLYDYFINKFGQEDSAN---FQVARENFIKSQAAYSVISYI 2133
Query: 1281 LGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVING 1340
L I DRHN NI++ GH+ HIDFG F+ D N + + A F LT +M+ ++ G
Sbjct: 2134 LQIKDRHNGNILINDKGHIIHIDFG-FIFDISPANNLR----FESANFKLTKEMIQIM-G 2187
Query: 1341 GERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
G + ++ FQ++V L F +R + +HI + L
Sbjct: 2188 GSKDSEAFQYYVNLTIKGFLTMRNYFEHIYNTIRL 2222
>UniRef50_A0BJY8 Cluster: Chromosome undetermined scaffold_111, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_111, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2327
Score = 106 bits (255), Expect = 4e-21
Identities = 72/213 (33%), Positives = 111/213 (52%), Gaps = 17/213 (7%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGM-IEIVTEAETLR 1229
+FKV DD+RQD L LQ+I + ++ + GLDL + ++ + K + + + E
Sbjct: 2062 IFKVFDDIRQDNLALQIISMFKGVFERCGLDLHVFPYKTISNRTGKSLNVGGIIEVVPNT 2121
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKHNPSE--LEYQRARDNFTASCAGYSVATYLLGICDRH 1287
+ + G T + E+ +E L++Q AR+NF S A YS+ +Y+L I DRH
Sbjct: 2122 ISRDQLGKTNRCT---LYEYFINKFGAEDSLQFQIARENFIKSQAAYSIISYILQIKDRH 2178
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPT-- 1345
N NI++ GHL HIDFG F+ D GN K + A F LT +M ++ GGE
Sbjct: 2179 NGNILISDKGHLIHIDFG-FIFDISPGGNLK----FESANFKLTKEMSQIM-GGEVSNNM 2232
Query: 1346 ---QRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
Q F ++V+L AF +R +++H L L
Sbjct: 2233 LSYQAFNYYVDLTVRAFLAIRHYYEHFYYLVTL 2265
>UniRef50_Q4Q2I5 Cluster: Phosphatidylinositol 4-kinase, putative;
n=3; Leishmania|Rep: Phosphatidylinositol 4-kinase,
putative - Leishmania major
Length = 611
Score = 106 bits (254), Expect = 5e-21
Identities = 65/199 (32%), Positives = 108/199 (54%), Gaps = 14/199 (7%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDLRQ+ L LQ+I +W +AGL +R+ + ALPT G++E++ ++ ++ +I+
Sbjct: 355 KAGDDLRQEELALQLIHTFQCIWQEAGLTVRVKPYAALPTHRDCGLLEVIEDSASMDSIK 414
Query: 1233 TEWGLTGSFKDKPIAEWLAKHNPSE-LEYQRARDNFTASCAGYSVATYLLGICDRHNDNI 1291
++ + +L ++ + + Y++A+ NF S AGYS+ Y+L I DRHN N+
Sbjct: 415 KATRVSSIYN-----YYLKAYDGEDSVLYRKAQQNFVESMAGYSIICYILQIKDRHNGNL 469
Query: 1292 MLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHF 1351
M++ G L HIDFG FL G + + APF L+ +++ V+ G + F +F
Sbjct: 470 MIQRDGSLVHIDFG-FLFVTSPGG-----LNFESAPFKLSQELIDVMGGAS--SDAFNYF 521
Query: 1352 VELCCMAFNIVRAHHDHIL 1370
L A R + IL
Sbjct: 522 RILVYEALAAARERCEDIL 540
>UniRef50_Q5KEG3 Cluster: 1-phosphatidylinositol 4-kinase, putative;
n=2; Filobasidiella neoformans|Rep:
1-phosphatidylinositol 4-kinase, putative - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 1251
Score = 105 bits (252), Expect = 9e-21
Identities = 71/216 (32%), Positives = 107/216 (49%), Gaps = 15/216 (6%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
VI + K G DLRQ+ L Q+I+ +W + D F+ L T + G++E VT+A
Sbjct: 979 VISVIVKTGADLRQEQLATQLIERFSRIWKEENCDCWARFFRILITGETSGLVETVTDAV 1038
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEW-LAKH------NPSELEYQRARDNFTASCAGYSVATY 1279
++ +I+ + PI L H P + RA+ NF S AGYS+ TY
Sbjct: 1039 SVHSIKKGEYAKRLAEGGPIGHVSLMDHYVNTFGKPDSGRFARAQRNFIRSLAGYSIITY 1098
Query: 1280 LLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVIN 1339
LL I DRHN NI++ GHL HIDFG L ++ GN + + APF + + V ++
Sbjct: 1099 LLQIKDRHNGNILVDQDGHLIHIDFGFMLSNSP--GN----MGFEAAPFKMLMEYVDIMG 1152
Query: 1340 GGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
G + P + +F +L F R H D ++ + L
Sbjct: 1153 GLDSP--GYAYFKKLFKEGFEAARKHSDSLITIVEL 1186
>UniRef50_A2F7A3 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Trichomonas vaginalis G3|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Trichomonas vaginalis G3
Length = 1396
Score = 105 bits (251), Expect = 1e-20
Identities = 62/201 (30%), Positives = 111/201 (55%), Gaps = 15/201 (7%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK+ DD+RQDA++ Q I++ ++ AG+D + ++ T ++G+IE++ ++++
Sbjct: 1141 IFKIHDDVRQDAMMYQFIEVFKGIFRDAGIDCFVYPYRVFATGENRGVIELIPKSKSRHD 1200
Query: 1231 IQTEWGLTGSFKDKPIAEW-LAKHNP-SELEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
I GS ++ + + ++K+ + +A++NF S A S+ YL + DRHN
Sbjct: 1201 I-------GSATNEDLLHYFISKYGQIGTAAFNKAQENFVRSMAPNSLICYLFQVKDRHN 1253
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
NIM+ GH+ HIDFG F+ + GN K +RAPF L+ +M+ ++ GG + F
Sbjct: 1254 ANIMIDEDGHVIHIDFG-FIFEISPGGNMK----FERAPFKLSKEMIDLM-GGSKEAAPF 1307
Query: 1349 QHFVELCCMAFNIVRAHHDHI 1369
+ F +L RA H+ I
Sbjct: 1308 KLFRKLLIQCMFAARARHEEI 1328
>UniRef50_A6R342 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized
protein - Ajellomyces capsulatus NAm1
Length = 1959
Score = 105 bits (251), Expect = 1e-20
Identities = 65/171 (38%), Positives = 98/171 (57%), Gaps = 11/171 (6%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I ++++ GLD+ + ++ T+ G+I+++ + +
Sbjct: 1673 AIFKVGDDCRQDVLALQMIAAFRSIFMGIGLDVFVYPYRVTATAPGCGVIDVLPNSISRD 1732
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHND 1289
+ E + G + D I+++ + + +Q AR NF S A YSV +YLL DRHN
Sbjct: 1733 MLGRE-AVNGLY-DYFISKYGGEQST---RFQEARSNFVKSMAAYSVISYLLQFKDRHNG 1787
Query: 1290 NIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVING 1340
NIM+ +GH+ HIDFG F D G V +RAPF LT +MV V+ G
Sbjct: 1788 NIMIDDAGHIIHIDFG-FCFDIAPGG-----VRFERAPFKLTSEMVAVMGG 1832
>UniRef50_Q9UW20 Cluster: Phosphatidylinositol 4-kinase PIK1alpha;
n=5; Saccharomycetales|Rep: Phosphatidylinositol 4-kinase
PIK1alpha - Candida albicans (Yeast)
Length = 977
Score = 105 bits (251), Expect = 1e-20
Identities = 69/217 (31%), Positives = 110/217 (50%), Gaps = 17/217 (7%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDL Q+A Q+I ++ +W K + + + L TS + G++E +T A ++ +I+
Sbjct: 708 KNGDDLPQEAFACQLISMISNIWKKNNIPVWTKRMKILITSANTGLVETITNAMSIHSIK 767
Query: 1233 ---TEWGLTGSFKDKPIAEWLAKH------NPSELEYQRARDNFTASCAGYSVATYLLGI 1283
TE + K L + +P+ ++ A+ NF S A YS+ Y+L I
Sbjct: 768 KSFTEHSIKSGENSKGKIFTLLDYFHSVFGSPNSTSFRTAQQNFAKSLAAYSIICYVLQI 827
Query: 1284 CDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER 1343
DRHN NIM+ GH+ HIDFG FL N V + APF LT + V ++ G +
Sbjct: 828 KDRHNGNIMVDGDGHIIHIDFG-FL-----LSNSPGSVGFEAAPFKLTVEYVELLGGVD- 880
Query: 1344 PTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
++ + FV LC F +R + + I+++ L DS
Sbjct: 881 -SEIYSQFVYLCKQCFKSLRDNSEEIIEIVELMQKDS 916
>UniRef50_Q0CTY2 Cluster: Putative uncharacterized protein; n=2;
Trichocomaceae|Rep: Putative uncharacterized protein -
Aspergillus terreus (strain NIH 2624)
Length = 1927
Score = 104 bits (250), Expect = 2e-20
Identities = 64/173 (36%), Positives = 100/173 (57%), Gaps = 11/173 (6%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I +++ GLD+ + ++ T+ G+I+++ + +
Sbjct: 1649 AIFKVGDDCRQDMLALQMIAAFRSIFSSIGLDVWVFPYRVTSTAPGCGVIDVLPNSISRD 1708
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHND 1289
+ E + G + D ++++ + + + +Q AR NF S A YSV +YLL DRHN
Sbjct: 1709 MLGRE-AVNGLY-DYFVSKYGGEDS---IRFQEARTNFVKSMAAYSVISYLLQFKDRHNG 1763
Query: 1290 NIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGE 1342
NIM+ +GH+ HIDFG F D G V +RAPF LT +MV V++G +
Sbjct: 1764 NIMVDDAGHIIHIDFG-FCFDIAPGG-----VRFERAPFKLTSEMVAVMSGAQ 1810
>UniRef50_A2R164 Cluster: Contig An13c0010, complete genome; n=5;
Eurotiomycetidae|Rep: Contig An13c0010, complete genome -
Aspergillus niger
Length = 1992
Score = 104 bits (250), Expect = 2e-20
Identities = 65/172 (37%), Positives = 97/172 (56%), Gaps = 13/172 (7%)
Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
A+FKVGDD RQD L LQ+I ++ GLD+ + ++ T+ G+I+++ + +
Sbjct: 1712 AIFKVGDDCRQDMLALQMIAAFRGIFASVGLDVWVFPYRVTSTAPGCGVIDVLPNSISRD 1771
Query: 1230 AIQTEWGLTGSFKDKPIAEWLAKHNPSE-LEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
+ E + G + +++K+ E + +Q AR NF S A YSV +YLL DRHN
Sbjct: 1772 MLGRE-AVNGLYD-----YFISKYGGEESIRFQEARTNFVKSMAAYSVISYLLQFKDRHN 1825
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVING 1340
NIM+ +GH+ HIDFG F D G V +RAPF LT +MV V++G
Sbjct: 1826 GNIMVDDAGHIIHIDFG-FCFDIAPGG-----VRFERAPFKLTSEMVAVMSG 1871
>UniRef50_Q4SSV6 Cluster: Chromosome undetermined SCAF14347, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14347, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1091
Score = 104 bits (249), Expect = 2e-20
Identities = 97/356 (27%), Positives = 149/356 (41%), Gaps = 50/356 (14%)
Query: 923 LLAATNWYGDHREQLIGLLRLWEKPSPLNAMHL-------LLPC-FPDVAVRETAAKLLN 974
LL++ W +E + RL E+ S ++ L LL C F D VR A + L
Sbjct: 617 LLSSVRW--GRQEDVSETHRLLERSSAWDSSRLDVGLALQLLDCHFSDAQVRSMAVRKLE 674
Query: 975 EMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQA 1034
+ DDD+ R L QL QA++ E Y FW L
Sbjct: 675 TLEDDDVLRYLLQLVQAVKFEPYHDSSLVRFLLKRALRSKRIGHFLFWFL---------- 724
Query: 1035 PHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLC 1094
+E SM R+ ++L A L CGE++ + +Q + ++L
Sbjct: 725 ----------------RSEIAQSMHYQQRFAVLLEAYLRGCGEDMLQDFRKQVEITEALQ 768
Query: 1095 EMAVSVKCAKEXXXXXXXXXXXXXXXXXXXXQPTALPLALHKYVHD-------LDVKSCT 1147
++ +K Q + LP + +D L ++ C
Sbjct: 769 KVTREIKAVSAEKYDITAQVVFQLRQKLEALQSSGLPEDF-RVPYDPGLRAGALLIEQCK 827
Query: 1148 YFSSNTLPLKINFIGTDNAV-----IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDL 1202
+S PL + F D + I +FK GDDLRQD L+LQ++ IM+++W LDL
Sbjct: 828 VMASKKKPLWLQFKRADGSTLSKDPIGIIFKDGDDLRQDMLILQILLIMESIWETESLDL 887
Query: 1203 RMVTFQALPTSNSKGMIEIVTEAETLRAI-QTEWGLTGSFKDKPIAEWLAKHNPSE 1257
++ + + T N GMIEIV +A T+ I Q+ G TG+FKD+ + +WL SE
Sbjct: 888 CLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAFKDEILCQWLRDKCVSE 943
Score = 39.9 bits (89), Expect = 0.52
Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 6/92 (6%)
Query: 439 VVCSLDEDIREDMSGYMLRVRGAKEYLTPGSSLSEYDYIRECVRLEKDVTLCLHEGRDST 498
V+ + E++ E + ++LRV G +EYL L ++++IR+C++ +D+ L L +
Sbjct: 242 VLLGIPENVCE--ADFVLRVCGREEYLYGDKPLQDFNWIRQCLKNGEDIHLVLESPPNPD 299
Query: 499 LARTERDDAKDSHLTLDDLFPAQGATPMLSFD 530
L +++D +DD A G L+ D
Sbjct: 300 LDLVQKED----WAQVDDCTGAAGTHEQLTID 327
>UniRef50_A5DM56 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 958
Score = 104 bits (249), Expect = 2e-20
Identities = 76/220 (34%), Positives = 107/220 (48%), Gaps = 29/220 (13%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
MFK+GDDLRQD LV+Q++ +MD L LDLR+ ++ L TS G+I+ V +TL +
Sbjct: 688 MFKIGDDLRQDQLVIQIMNLMDQLLKNENLDLRLTPYKILATSPIAGLIQFVPN-QTLDS 746
Query: 1231 IQTEWG--------LTGSFKDKPIAEWLAKHNPSELEYQRA-----RDNFTASCAGYSVA 1277
+ G L + D A L + + DN+ SCAGY V
Sbjct: 747 VLAVGGPENGILHYLRAAQADATTARPLPGSSVHAVTSDMGVPALVMDNYVRSCAGYCVI 806
Query: 1278 TYLLGICDRHNDNIMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVY 1336
TYLLG+ DRH DN++L +G +H DFG LG D + F +L +
Sbjct: 807 TYLLGVGDRHLDNLLLSPNGKFWHADFGYILGRDPKPFPPLMKL-------------PIQ 853
Query: 1337 VING-GERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
VI G G R + F F C + + +R + IL+LF L
Sbjct: 854 VIEGMGGREHENFHIFQNYCFITYTTLRKSSNLILNLFQL 893
>UniRef50_Q9C680 Cluster: Phosphatidylinositol 4-kinase, putative;
n=18; Magnoliophyta|Rep: Phosphatidylinositol 4-kinase,
putative - Arabidopsis thaliana (Mouse-ear cress)
Length = 525
Score = 103 bits (248), Expect = 3e-20
Identities = 82/254 (32%), Positives = 121/254 (47%), Gaps = 35/254 (13%)
Query: 1130 LPLALHKYVHDLDVKS-CTYFSSNTLPLKINFI-----GTDNAVIP--AMFKVGDDLRQD 1181
LP A +K V + V S S+ +P+ I F G N V P +FKVGDD RQD
Sbjct: 226 LPTAPNKLVRVIQVDSGIPLQSAAKVPIMITFNVVDLDGDHNDVKPQACIFKVGDDCRQD 285
Query: 1182 ALVLQVIKIMDTLWLKAGLDLRMVTFQALPT----SNSKGMIEIVTEAETLRAIQTEWGL 1237
L LQVI ++ ++ GL+L + + LPT + S+ + T+ Q +GL
Sbjct: 286 VLALQVISLLGDIFQAVGLNLYLFPYGVLPTVVPNTRSRSQMGETTDGGLYEIFQQNYGL 345
Query: 1238 TGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSG 1297
GS ++ AR NF S AGY+VA+ LL DRHN N++ G
Sbjct: 346 VGS-----------------TTFETARANFLISSAGYAVASLLLQPKDRHNGNLLFDDVG 388
Query: 1298 HLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVIN-GGERPTQRFQHFVELCC 1356
L HIDFG F+ + GN + + A F L+H+M +++ G ++ + FV LC
Sbjct: 389 RLVHIDFG-FILETSPGGNMR----FENAHFKLSHEMTQLLDPSGVMKSKTWHQFVSLCV 443
Query: 1357 MAFNIVRAHHDHIL 1370
+ R + D I+
Sbjct: 444 KGYLAARRYMDEII 457
>UniRef50_Q9UW24 Cluster: Phosphatidylinositol 4-kinase PIK1a; n=3;
Saccharomycetales|Rep: Phosphatidylinositol 4-kinase
PIK1a - Candida albicans (Yeast)
Length = 956
Score = 103 bits (248), Expect = 3e-20
Identities = 77/241 (31%), Positives = 119/241 (49%), Gaps = 24/241 (9%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDL Q+A Q+I ++ +W K +D + L TS + G++E +T A ++ +I+
Sbjct: 687 KNGDDLPQEAFACQLISLISNIWKKHKVDFWTKRMKILITSANAGLVETITNAMSIHSIK 746
Query: 1233 ---TEWGLTGSFKDK----PIAEWLAKHNPS--ELEYQRARDNFTASCAGYSVATYLLGI 1283
TE + K + ++ K S +Y +A++NF S A YS+ Y+L I
Sbjct: 747 KSLTELSIENGENAKGRIFTLKDYFQKLYGSVDSSKYVKAQENFAISLASYSIICYVLQI 806
Query: 1284 CDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER 1343
DRHN NIML GH+ HIDFG FL N V + APF LT + V V+ G E
Sbjct: 807 KDRHNGNIMLDHEGHIIHIDFG-FL-----LSNSPGSVGFEAAPFKLTSEYVEVLGGLE- 859
Query: 1344 PTQRFQHFVELCCMAFNIVRAHHDHILDLF-------ALPSCDSGGSERTVAGGRPQMSL 1396
++ + FV+ C F +R I+ + +LP ++G + + R Q+ L
Sbjct: 860 -SKAYLKFVDTCKNCFKALRKEWGQIVSIVELMQKGSSLPCFNNGDNTSVLLQQRLQLHL 918
Query: 1397 S 1397
S
Sbjct: 919 S 919
>UniRef50_Q4FXQ9 Cluster: Phosphatidylinositol-kinase domain protein,
putative; n=3; Leishmania|Rep:
Phosphatidylinositol-kinase domain protein, putative -
Leishmania major strain Friedlin
Length = 2662
Score = 103 bits (247), Expect = 4e-20
Identities = 61/170 (35%), Positives = 94/170 (55%), Gaps = 14/170 (8%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK+GDD RQD + LQ+I +M + G+ + ++ + T S G+IE V + +
Sbjct: 2390 IFKMGDDCRQDQISLQLIGLMQRILNSIGVPSFLYPYRVITTGKSSGVIECVPRSRSRNE 2449
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKH--NPSELEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
I G + +AE+ + +P ++RAR+NF S A YSV +++L I DRHN
Sbjct: 2450 I-------GKLVESNVAEFFVQTFGHPESAGFRRARENFVRSTAAYSVVSFILNIKDRHN 2502
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI 1338
NIM+ G+L HIDFG FL D G+ + + +PF LT +MV +I
Sbjct: 2503 GNIMIDADGNLVHIDFG-FLFDTSPGGD----INFESSPFKLTTEMVQLI 2547
>UniRef50_Q16WA0 Cluster: Phosphatidylinositol 4-kinase; n=1; Aedes
aegypti|Rep: Phosphatidylinositol 4-kinase - Aedes
aegypti (Yellowfever mosquito)
Length = 1234
Score = 103 bits (246), Expect = 5e-20
Identities = 64/206 (31%), Positives = 108/206 (52%), Gaps = 11/206 (5%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ A+ K GDDLRQ+ + Q++++ +W + +DL + ++ + SN G+IE +
Sbjct: 972 LLSAIVKCGDDLRQELMATQLLEMFQLIWKEENVDLWVRPYKIVCLSNDSGLIEPILNTV 1031
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286
+L I+ + S D E+ S+ ++ A+ NF SCA Y + +YLL + DR
Sbjct: 1032 SLHQIKKN--SSKSLSDYFADEYGGDSEDSD-RFRTAQRNFMQSCAAYCLISYLLQVKDR 1088
Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346
HN NI+L + GHL HIDFG L + K L + +++PF LT + V V+ G ++
Sbjct: 1089 HNGNILLHSDGHLIHIDFGFILSISP-----KNLGF-EQSPFKLTPEFVDVMGGPS--SE 1140
Query: 1347 RFQHFVELCCMAFNIVRAHHDHILDL 1372
+ F L R H D I+++
Sbjct: 1141 LWLEFKYLLLEGLKAARKHMDRIINI 1166
>UniRef50_A7AWF1 Cluster: Phosphatidylinositol 3-and 4-kinase domain
containing protein; n=1; Babesia bovis|Rep:
Phosphatidylinositol 3-and 4-kinase domain containing
protein - Babesia bovis
Length = 1151
Score = 102 bits (245), Expect = 7e-20
Identities = 53/139 (38%), Positives = 79/139 (56%), Gaps = 8/139 (5%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK DDLR D L Q+ + TL G+ + T++ +PTS++ G ++IV E + L
Sbjct: 903 LFKYKDDLRLDQLCQQIAMLCRTLLEGHGVKSYIFTYKVVPTSHNDGFLDIVDETKALSD 962
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
I ++G G + + + NPS E R NF S A YS TY+LG+ DRHNDN
Sbjct: 963 ILNDYGSIGGY--------VFEDNPSAFEEFCRRLNFVGSLAAYSAITYILGVGDRHNDN 1014
Query: 1291 IMLKTSGHLFHIDFGKFLG 1309
+++ SGH+ H+D+G LG
Sbjct: 1015 LIISRSGHVIHVDYGYILG 1033
>UniRef50_UPI00006CFDD2 Cluster: Phosphatidylinositol 3- and 4-kinase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3- and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 891
Score = 101 bits (242), Expect = 2e-19
Identities = 82/265 (30%), Positives = 128/265 (48%), Gaps = 37/265 (13%)
Query: 1147 TYFSSNTLPLKINF----IGTDN--AVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGL 1200
T F S P+K+ F IG + ++K GDDLRQD LV+Q+ +MD L G
Sbjct: 589 TVFKSAMAPIKMTFTSYPIGQKEKEGKVEMIYKNGDDLRQDQLVMQIFNLMDGLLKGVGQ 648
Query: 1201 DLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSF-------KDKPIAEW---L 1250
D R++ ++ L S + G +E V + T++ + + + PI E L
Sbjct: 649 DFRLMPYKVLACSKNDGFMEFVPNSTTIQDLLKGGKQFSQYLQNLAANPENPIYEEYKRL 708
Query: 1251 AKHNP-----SELEY--QRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHID 1303
N S +EY Q+ +N+ SCAGYSV TY LG+ DRH +N+M+ +G FHID
Sbjct: 709 RMQNDEQGKLSNIEYVSQKIMENYMLSCAGYSVMTYFLGVGDRHLENLMVDITGKFFHID 768
Query: 1304 FGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIV 1362
FG LG D + + P L M+ + G + ++ + F + C A+ +
Sbjct: 769 FGFILGQDPKPY----------PPPLKLCRQMIEGMGG--KDSKVYAEFRKKCVHAYIYL 816
Query: 1363 RAHHDHILDLFALPSCDSGGSERTV 1387
R + I++LF L DSG + ++
Sbjct: 817 RKYAKLIVNLFHL-MIDSGIKDMSI 840
Score = 39.1 bits (87), Expect = 0.91
Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 21/107 (19%)
Query: 909 RQYLVQIPGALPLVLLAATNWYGDHREQLIG---LLRLWEKPSPLNAMHLLLPCF----- 960
R LVQ P AL + L + NW D++++L LL++W K S +A+HLL F
Sbjct: 343 RYSLVQNPEAL-VKFLHSINW--DNQKELNEAKKLLKIWAKCSYGDALHLLSSSFCANEF 399
Query: 961 --------PDVA--VRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
D A +R+ A + L + +C +L QLTQALR+E +
Sbjct: 400 YNKKYKKPQDTAIYIRKYACEQLEKEQTSTICSILLQLTQALRYEPF 446
>UniRef50_UPI00003BFBA7 Cluster: PREDICTED: similar to four wheel
drive CG7004-PA, isoform A; n=1; Apis mellifera|Rep:
PREDICTED: similar to four wheel drive CG7004-PA, isoform
A - Apis mellifera
Length = 1078
Score = 101 bits (241), Expect = 2e-19
Identities = 73/240 (30%), Positives = 120/240 (50%), Gaps = 25/240 (10%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ + K GDDLRQ+ L Q++ ++ +W + L + ++ L SN G+IE +
Sbjct: 818 LLAVIVKCGDDLRQELLASQLLSMLQKIWQDEHVPLWVRPYKILCLSNDSGLIEPILNTV 877
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKH-NPSELE-YQRARDNFTASCAGYSVATYLLGIC 1284
+L ++ + LT + ++ + PS E + A+ NF SCA Y + YL+ +
Sbjct: 878 SLHQVKKQCQLT-------LYQYFEREFGPSMSEAFIIAQRNFIQSCAAYCLVCYLIQVK 930
Query: 1285 DRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERP 1344
DRHN NI+L + GHL HIDFG L + R + + +PF LT + V V+ G +
Sbjct: 931 DRHNGNILLHSDGHLIHIDFGFILSTS------PRNLGFETSPFKLTPEFVEVMGGSQ-- 982
Query: 1345 TQRFQHFVELCCMAFNIVRAHHDHILDLF-------ALPSCDSGGSERTVAGGRPQMSLS 1397
+++FQ F L R H + I++L LP SGG+ TV G + + L+
Sbjct: 983 SKQFQEFKTLILQGLIAARKHMEKIVNLVEIMLSGSQLPCFRSGGA-ATVQGLKNRFHLT 1041
>UniRef50_Q4RFL9 Cluster: Chromosome undetermined SCAF15114, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF15114, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 989
Score = 101 bits (241), Expect = 2e-19
Identities = 98/308 (31%), Positives = 139/308 (45%), Gaps = 69/308 (22%)
Query: 1126 QPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVL 1185
+P LPL + + ++ T F S +P K+ F D A+ P +FK GDDLRQD L+L
Sbjct: 632 EPIPLPLEPQIRITGIVPETATLFKSALMPAKLIFKAEDGAMYPVIFKHGDDLRQDQLIL 691
Query: 1186 QVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAET------------LRAIQT 1233
Q+I +MD L K LDL++ ++ L TS G + + I
Sbjct: 692 QIISLMDKLLRKENLDLKLTPYKVLATSTKHGKPPFASSLDVHHLSNFGATILDFATISP 751
Query: 1234 EWGLTGS-----FKDKPIAEWLA----------KHNPSEL-EY---QRARDNFTASCAGY 1274
+T S + P+AE LA KH PSE Y D + SCAGY
Sbjct: 752 PGSVTPSGFMQFVQSVPVAEVLATEGNIQSFFRKHAPSEKGPYGISSEVMDTYVKSCAGY 811
Query: 1275 SVATYLLGICDRHNDNIML-KTS--------------------------GHLFHIDFGKF 1307
V TY+LG+ DRH DN++L KT G LFHIDFG
Sbjct: 812 CVITYILGVGDRHLDNLLLTKTGGKEPGFVSMGLPGIQVFWFETGCVSPGKLFHIDFGYI 871
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHD 1367
LG + K L P L+ +MV + G + ++++Q F + C AF +R + +
Sbjct: 872 LG-----RDPKPL----PPPMKLSKEMVEGMGGTQ--SEQYQEFRKQCYTAFLHLRRYSN 920
Query: 1368 HILDLFAL 1375
IL+LF+L
Sbjct: 921 LILNLFSL 928
Score = 53.2 bits (122), Expect = 5e-05
Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 4/134 (2%)
Query: 867 SLKDLPSFDSL--DGHTQSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLL 924
SL+ PS L + T+ QL ++ +++ +E ++++W+ R YL AL L
Sbjct: 307 SLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLSSEEQDLVWKFRYYLTTQEKALTK-FL 365
Query: 925 AATNW-YGDHREQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCR 983
NW +Q + LL W +++ LL F + VR A L + D+DL
Sbjct: 366 KCVNWDLPQEAKQALELLGKWRPMDVEDSLELLSSQFTNPTVRRYAVARLQQADDEDLLM 425
Query: 984 VLPQLTQALRHETY 997
L QL QAL++E +
Sbjct: 426 YLLQLVQALKYENF 439
>UniRef50_Q4SZT6 Cluster: Chromosome undetermined SCAF11492, whole
genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome undetermined SCAF11492, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 818
Score = 100 bits (240), Expect = 3e-19
Identities = 54/146 (36%), Positives = 83/146 (56%), Gaps = 9/146 (6%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++P + K GDDLRQ+ L QV++ + ++W + + L + ++ L S+ GMIE V A
Sbjct: 506 LLPVIVKCGDDLRQELLAYQVLRQLQSIWQQERVPLWIKPYKILVMSSDSGMIEPVLNAV 565
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELE-YQRARDNFTASCAGYSVATYLLGICD 1285
+L + ++ L F L +H + E + A+ NF SCAGYS+ YLL + D
Sbjct: 566 SLHQVLSQLSLLDYF--------LQEHGAATSEAFLSAQRNFVQSCAGYSLICYLLQVKD 617
Query: 1286 RHNDNIMLKTSGHLFHIDFGKFLGDA 1311
RHN NI+L + GH+ HIDFG L +
Sbjct: 618 RHNGNILLDSEGHIIHIDFGFILSSS 643
>UniRef50_UPI0000D5729C Cluster: PREDICTED: similar to CG7004-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7004-PA, isoform A - Tribolium castaneum
Length = 874
Score = 99.1 bits (236), Expect = 8e-19
Identities = 65/211 (30%), Positives = 107/211 (50%), Gaps = 15/211 (7%)
Query: 1163 TDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIV 1222
T ++ + K GDDLRQ+ + Q++++ +W + L + ++ L SN G+IE +
Sbjct: 611 TSWTLLSVIVKCGDDLRQELMASQLLQMFQKIWEMEHVPLWVHPYRILCLSNDSGLIEPI 670
Query: 1223 TEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELE-YQRARDNFTASCAGYSVATYLL 1281
+L I+ L+ + ++ ++ P E + A+ NF SCA Y + YL+
Sbjct: 671 LNTVSLHQIKKHRQLS------LLEYFINEYGPITCEEFLTAQKNFVQSCAAYCLFCYLI 724
Query: 1282 GICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGG 1341
+ DRHN NI+LK+ GHL HIDFG L + K L + + +PF LT + V V+ G
Sbjct: 725 QVKDRHNGNILLKSDGHLIHIDFGFILSMSP-----KNLGF-ETSPFKLTAEFVEVMGGD 778
Query: 1342 ERPTQRFQHFVELCCMAFNIVRAHHDHILDL 1372
+ + F++F L R H D I+ L
Sbjct: 779 Q--SDMFEYFKILILQGLVAARKHMDMIVPL 807
>UniRef50_A4VDF9 Cluster: Phosphatidylinositol 4-kinase; n=1;
Tetrahymena thermophila SB210|Rep: Phosphatidylinositol
4-kinase - Tetrahymena thermophila SB210
Length = 865
Score = 99.1 bits (236), Expect = 8e-19
Identities = 64/207 (30%), Positives = 106/207 (51%), Gaps = 12/207 (5%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ + K GD+++Q+ +Q+I D ++ LDL++ ++ + G++E+V +
Sbjct: 598 LVHMIVKTGDNIKQEQFAVQLIYQFDQIFKMEELDLKLTPYEIVSLGPQSGILEMVKNSI 657
Query: 1227 TLRAIQTEWGLTGSFKD-KPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICD 1285
TL + + S+K+ K + + + S+ +++A+ NF +S A YS+ Y L I D
Sbjct: 658 TLDGLLKQ---IHSYKEIKDLRHFFQLYYGSQ--FKKAQYNFCSSLAAYSLVCYFLQIKD 712
Query: 1286 RHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPT 1345
RHN NI+L +GH+ HIDFG FL +A K L PF L D + ++ G E +
Sbjct: 713 RHNGNILLHKNGHIIHIDFGFFLSNAP----GKGLSIEQNVPFKLLSDYISILGGIE--S 766
Query: 1346 QRFQHFVELCCMAFNIVRAHHDHILDL 1372
FQ F L F H D IL L
Sbjct: 767 DMFQTFRRLFFQGFQAACKHQDKILIL 793
>UniRef50_A4VDB8 Cluster: Phosphatidylinositol 4-kinase; n=1;
Tetrahymena thermophila SB210|Rep: Phosphatidylinositol
4-kinase - Tetrahymena thermophila SB210
Length = 1748
Score = 98.7 bits (235), Expect = 1e-18
Identities = 64/202 (31%), Positives = 105/202 (51%), Gaps = 15/202 (7%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK GDDLRQ+ L +Q+I +++ KA L L + ++ + TS S G+IE + ++
Sbjct: 1496 IFKGGDDLRQELLAMQLIYKFQSIFQKANLQLWLRPYEIIVTSASSGIIEFLPNTYSIDG 1555
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
++ + D ++ K ++Q+A+ NF S AGYS+ YLL DRHN N
Sbjct: 1556 LKKKVPKFTCLYDF-YKDYFGK------QFQQAQSNFIESLAGYSIVCYLLQFKDRHNGN 1608
Query: 1291 IMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQH 1350
I++ SGHL HID+G MF + + APF LT + ++ G E ++ F+
Sbjct: 1609 ILIDNSGHLIHIDYG------FMFCISPGGINFENAPFKLTKEYAQLMGGKE--SEGFER 1660
Query: 1351 FVELCCMAFNIVRAHHDHILDL 1372
+ L F ++ + D I+ L
Sbjct: 1661 YKNLVFQGFKELQKYVDEIIFL 1682
>UniRef50_Q2H8U5 Cluster: Putative uncharacterized protein; n=4;
Pezizomycotina|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 1016
Score = 98.7 bits (235), Expect = 1e-18
Identities = 65/203 (32%), Positives = 100/203 (49%), Gaps = 19/203 (9%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ + K G DLRQ+A Q+I++ +W+ AG+ + + + L T S G+IE +
Sbjct: 718 LVSVIIKTGSDLRQEAFACQLIRVCHKIWVDAGVPVWVKLMRILVTGESSGLIETIANGV 777
Query: 1227 TLRAIQTEWGL----TGSFKDKPIAEWLAKHN------PSELEYQRARDNFTASCAGYSV 1276
+L +I+ L +G + IA L H P ++ D F S A YSV
Sbjct: 778 SLHSIKRSLTLASIESGQNPRRRIAT-LKDHFVKAFGIPEGESFRAGVDAFKRSLAAYSV 836
Query: 1277 ATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVY 1336
+Y+L + DRHN N+++ GH+ HIDFG M N V + APF LT++ V
Sbjct: 837 ISYVLQLKDRHNGNVLIDNEGHIIHIDFG------FMLSNSPGSVGFEAAPFKLTYEYVD 890
Query: 1337 VINGGERPTQRFQHFVELCCMAF 1359
V+ G P F+ + LC AF
Sbjct: 891 VLGGVGSPD--FEDYKSLCKQAF 911
>UniRef50_Q4S209 Cluster: Chromosome undetermined SCAF14764, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF14764, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 2216
Score = 98.3 bits (234), Expect = 1e-18
Identities = 63/186 (33%), Positives = 101/186 (54%), Gaps = 16/186 (8%)
Query: 1180 QDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAI--QTEWGL 1237
QD L LQ+I + ++ GLDL + ++ + T+ G+IE + + ++ + QT++G+
Sbjct: 1947 QDMLALQIIGLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCKSRDQLGRQTDFGM 2006
Query: 1238 TGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSG 1297
F+++ E S L +Q+AR NF S A YS+ +LL I DRHN NIML + G
Sbjct: 2007 YDYFRNQYGDE-------STLAFQKARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDSKG 2059
Query: 1298 HLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCM 1357
HL HIDFG F+ ++ GN + P + D + +I GG+ F+ F+E+C
Sbjct: 2060 HLIHIDFG-FMFESSPGGN------LGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVR 2112
Query: 1358 AFNIVR 1363
+ VR
Sbjct: 2113 GYLAVR 2118
>UniRef50_A2YTT1 Cluster: Putative uncharacterized protein; n=2; Oryza
sativa|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 1047
Score = 98.3 bits (234), Expect = 1e-18
Identities = 97/356 (27%), Positives = 140/356 (39%), Gaps = 27/356 (7%)
Query: 935 EQLIGLLRLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRH 994
+Q + L+ WE +A+ LL P F + VR A +L SD++L L QL Q LR
Sbjct: 374 KQAVALIPRWESIDVADALGLLSPVFQNEEVRAYAVGVLERASDEELQCYLLQLVQGLRF 433
Query: 995 ETYXXXXXXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAET 1054
E W LV L + A LED +
Sbjct: 434 ERSDRSRLAHFLVNRALSNYELASFLRWYLVVELHDPSHARRYLCTYEMLEDAIMRSVHK 493
Query: 1055 DASMSASWRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXX 1114
+ + W+ +L+ +A L LR ++K L + A+
Sbjct: 494 EENGFQVWQ-SLIEQAELT--------AQLRS--IMKELSNVKHD---AQTKGRILEQLF 539
Query: 1115 XXXXXXXXXXXQPTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKV 1174
+P PL + + + F S PL I F + +FK
Sbjct: 540 SGIFSELKNFSEPIPSPLTPTVLLDGIVPEESLVFKSANYPLCIAFSTVNGGTSKMIFKK 599
Query: 1175 GDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTE 1234
GD+LR+D LV+Q+I +MD L LDL + +Q L T +G++E + + IQ
Sbjct: 600 GDNLRKDQLVIQIISLMDRLLKSDNLDLHLTPYQVLATGLEEGLVEFIPSISVAKIIQK- 658
Query: 1235 WGLTGSFKDKPIAEWLAKHNPSELE----YQRARDNFTASCAGYSVATYLLGICDR 1286
TGS I +L K NP E + + F SCAGYSV TY+LGI DR
Sbjct: 659 ---TGS-----IESYLQKCNPDEDGPFGITAQCLETFIKSCAGYSVITYILGIGDR 706
Score = 45.2 bits (102), Expect = 0.014
Identities = 31/98 (31%), Positives = 45/98 (45%), Gaps = 15/98 (15%)
Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERP-- 1344
H DN++L+ G LFH+DF LG+ P L +MV + G ER
Sbjct: 792 HLDNLLLQDDGRLFHVDFSYMLGEQ------PHRFAPPSPPMKLCKEMVEAMGGTERYLF 845
Query: 1345 -------TQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
++ + F CC A+NI+R + IL+LF L
Sbjct: 846 FACDFHFSEYYARFKSYCCEAYNILRKSSNLILNLFYL 883
>UniRef50_Q20077 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 666
Score = 98.3 bits (234), Expect = 1e-18
Identities = 70/222 (31%), Positives = 108/222 (48%), Gaps = 18/222 (8%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
+IP + K GDDL Q+A Q++ LW + G+ L + ++ + + G+IE V +
Sbjct: 396 LIPVIVKTGDDLSQEAFAQQLLFTFKDLWHEEGVPLYLRPYKIVCIGSDAGLIEPVLDTL 455
Query: 1227 TLRAIQTEWGLTGSFK-DKPIAEWLAKHN------PSELE-YQRARDNFTASCAGYSVAT 1278
+L I+ LT F+ + + KH+ P E Y A+ NF S A YS+ +
Sbjct: 456 SLHQIKRH--LTNVFRMNGNVTTPSLKHHFENVFGPVNSETYVNAQKNFIQSTAAYSLVS 513
Query: 1279 YLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI 1338
Y L + DRHN NI+L GHL HID+G L + R + + APF LT +++ V+
Sbjct: 514 YYLQLKDRHNGNILLDMDGHLIHIDYGFLLSSS------PRNLGFETAPFKLTTEIIDVM 567
Query: 1339 NGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
G + + F +F L R HH I+ L + S S
Sbjct: 568 GGID--SDMFLYFKSLLLRGLMAARKHHRRIVSLAEIMSAGS 607
>UniRef50_A0BV54 Cluster: Chromosome undetermined scaffold_13, whole
genome shotgun sequence; n=5; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_13, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 826
Score = 98.3 bits (234), Expect = 1e-18
Identities = 64/205 (31%), Positives = 102/205 (49%), Gaps = 10/205 (4%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ + K GD+L+Q+ LQ+I D ++ K GL L++ ++ L GMIE++ A
Sbjct: 558 LVHLIIKTGDNLKQEQFALQLICQFDQIFKKEGLPLKLRYYEVLSLGPDCGMIEMIKNAT 617
Query: 1227 TLRAIQTEWGLTGS-FKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICD 1285
T+ ++Q + F D +++ + +E +A N+ S A Y + Y L + D
Sbjct: 618 TIDSLQKNLQKKYTQFSD--FSDFFRSFFRNNIE--QALQNYVQSLAAYCLVCYFLQVKD 673
Query: 1286 RHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPT 1345
RHN NI+L GHL HIDFG FL K + + + PF L D + V+ GG + T
Sbjct: 674 RHNGNILLDDEGHLIHIDFGFFLS----ISPGKGMEFEGKVPFKLLSDYIKVL-GGVKGT 728
Query: 1346 QRFQHFVELCCMAFNIVRAHHDHIL 1370
HF +L F + H + IL
Sbjct: 729 LFQDHFRKLFYKGFKACQKHQNEIL 753
>UniRef50_Q9UBF8 Cluster: Phosphatidylinositol 4-kinase beta; n=45;
Euteleostomi|Rep: Phosphatidylinositol 4-kinase beta -
Homo sapiens (Human)
Length = 816
Score = 98.3 bits (234), Expect = 1e-18
Identities = 65/207 (31%), Positives = 103/207 (49%), Gaps = 15/207 (7%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ + K GDDLRQ+ L QV+K + ++W + + L + ++ L S GMIE V A
Sbjct: 558 LLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAV 617
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELE-YQRARDNFTASCAGYSVATYLLGICD 1285
++ ++ + L S D +L +H E + A+ NF SCAGY + YLL + D
Sbjct: 618 SIHQVKKQSQL--SLLDY----FLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKD 671
Query: 1286 RHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPT 1345
RHN NI+L GH+ HIDFG L + R + + + F LT + V V+ G +
Sbjct: 672 RHNGNILLDAEGHIIHIDFGFILSSS------PRNLGFETSAFKLTTEFVDVMGGLD--G 723
Query: 1346 QRFQHFVELCCMAFNIVRAHHDHILDL 1372
F ++ L R H D ++ +
Sbjct: 724 DMFNYYKMLMLQGLIAARKHMDKVVQI 750
>UniRef50_Q22WE1 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 842
Score = 96.7 bits (230), Expect = 4e-18
Identities = 66/211 (31%), Positives = 111/211 (52%), Gaps = 16/211 (7%)
Query: 1169 PAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETL 1228
P + K GDDLRQ+ L++Q+I+ ++ + G+ L + ++ + S S G IE + ++
Sbjct: 588 PFIIKGGDDLRQELLIMQLIQKFHEIFKQGGVPLYLRPYEIIVASESSGFIEFLPNTLSI 647
Query: 1229 RAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
A++ ++ K + E+ + ++ A+ NF S AGYS+ YLL I DRHN
Sbjct: 648 DALKKKYP-----KFTNLYEFYRR--TFNDYFEEAQKNFIESLAGYSLICYLLQIKDRHN 700
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
NI++ GH+ HIDFG L A G K + A F LT++ V ++ G R + +F
Sbjct: 701 GNILIDNQGHIIHIDFGFTLSIAP--GGIK----FETAHFKLTNEYVALMGG--RNSDQF 752
Query: 1349 QHFVELCCMAFNIVRAHHDHILDLFALPSCD 1379
++ L AF ++ H + I +L + CD
Sbjct: 753 GYYKSLLVRAFIEIKKHVNTICNLVQI-MCD 782
>UniRef50_A0EDW6 Cluster: Chromosome undetermined scaffold_90, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_90, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 695
Score = 96.7 bits (230), Expect = 4e-18
Identities = 63/204 (30%), Positives = 104/204 (50%), Gaps = 10/204 (4%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ + K GD+L+Q+ LQ+I ++ K L L++ T+ S G++E+V +A
Sbjct: 429 LVHLIVKTGDNLKQEQFALQLINQFQMIFQKERLPLKLTTYDIQSLGPSSGIMEMVKDAA 488
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286
T+ +++ + L KD ++ + K+ + L +A+ NF S A YS+ Y L I DR
Sbjct: 489 TIDSLKKK--LNSIDKDITLSLFFKKYYGANLH--KAQRNFCCSLAAYSLICYFLQIKDR 544
Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346
HN NI+L SG + HIDFG F+ K L + PF L + + V+ G + ++
Sbjct: 545 HNGNILLHKSGKILHIDFGFFIS----ISPGKGLEFEKNVPFKLLSEYIDVLGGTK--SE 598
Query: 1347 RFQHFVELCCMAFNIVRAHHDHIL 1370
F F +L F + H D IL
Sbjct: 599 LFNLFRKLFFKGFVACQKHQDQIL 622
>UniRef50_Q5CK49 Cluster: Phosphatidylinositol 3-kinase, root isoform;
n=3; Cryptosporidium|Rep: Phosphatidylinositol 3-kinase,
root isoform - Cryptosporidium hominis
Length = 943
Score = 96.3 bits (229), Expect = 6e-18
Identities = 60/195 (30%), Positives = 101/195 (51%), Gaps = 19/195 (9%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
M+KVGDDLRQD LV+Q+++I L + + ++T++ P S G+IE + + ++ +
Sbjct: 686 MYKVGDDLRQDRLVVQLLEISYKLLNEWNANSSIITYKVTPFSQFDGLIEFLDDFSSIGS 745
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEY-QRARDNFTASCAGYSVATYLLGICDRHND 1289
I+ ++G K+ + W +N + F SCA YSV T++LG+ DRH D
Sbjct: 746 IRKKYG-----KNCILNYWANAYNTNINNIPHNVLTTFITSCAAYSVITFILGVGDRHLD 800
Query: 1290 NIMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRF 1348
N+++ SGH H+DFG G D + F P + +M+ + G + F
Sbjct: 801 NLLVGKSGHFLHVDFGYIFGEDPKPF----------PPPMKICSEMIEAMGG--LNSLGF 848
Query: 1349 QHFVELCCMAFNIVR 1363
+ FV+ CC + +R
Sbjct: 849 KLFVDKCCDYYRYIR 863
>UniRef50_Q4D3R3 Cluster: Phosphatidylinositol-kinase domain protein,
putative; n=3; Trypanosoma cruzi|Rep:
Phosphatidylinositol-kinase domain protein, putative -
Trypanosoma cruzi
Length = 2302
Score = 95.9 bits (228), Expect = 8e-18
Identities = 57/178 (32%), Positives = 94/178 (52%), Gaps = 14/178 (7%)
Query: 1163 TDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIV 1222
T+ + +FK+GDD RQD + LQ+I + ++ + + ++ + T +IE V
Sbjct: 2021 TETTIKACIFKMGDDCRQDQIALQIIGLFQRIYDAIQVPSYLYPYRVVTTGRDSAVIECV 2080
Query: 1223 TEAETLRAIQTEWGLTGSFKDKPIAEWLAKH--NPSELEYQRARDNFTASCAGYSVATYL 1280
A + I G + +AE+ + +P + + RAR+ F S A YSVA+++
Sbjct: 2081 PRAMSRDQI-------GKLVESNLAEYFVQTYGHPESVTFHRARECFIRSMASYSVASFV 2133
Query: 1281 LGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI 1338
L + DRHN N+M+ GHL HIDFG FL D G+ + + +PF LT +MV ++
Sbjct: 2134 LNVKDRHNGNLMIDAHGHLVHIDFG-FLFDFSPGGD----INFESSPFKLTAEMVQLM 2186
>UniRef50_Q4CMW1 Cluster: Phosphatidylinositol 4-kinase, putative;
n=3; Trypanosoma|Rep: Phosphatidylinositol 4-kinase,
putative - Trypanosoma cruzi
Length = 584
Score = 95.1 bits (226), Expect = 1e-17
Identities = 65/212 (30%), Positives = 108/212 (50%), Gaps = 16/212 (7%)
Query: 1166 AVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEA 1225
+V+ + K DDLRQ+ L LQ+I I + +W + G+ + +AL S G++E + A
Sbjct: 321 SVVSVVVKAKDDLRQEELALQLIDIFNKIWEEGGITCSVRPHRALSVSADSGIMEYLDGA 380
Query: 1226 ETLRAIQTEWGLTGSFKDKPIAEWLAK-HNPSELE-YQRARDNFTASCAGYSVATYLLGI 1283
++ I+ ++ +A++ + P E + +A NF + AGYS+ +Y+L +
Sbjct: 381 CSIDGIKKLCQVSS------LAQFFNEAFGPVGSERHSKAEMNFVETMAGYSIVSYMLQV 434
Query: 1284 CDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER 1343
DRHN N+M+ + GHL HIDFG MF + + APF L+ +++ V+ G
Sbjct: 435 KDRHNGNLMISSEGHLVHIDFG------FMFATSPGGINFESAPFKLSQELMEVMGG--V 486
Query: 1344 PTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+ F +F L VR D IL L +L
Sbjct: 487 GSAAFNYFKLLLYQGMVAVRERADDILGLVSL 518
>UniRef50_A0CV19 Cluster: Chromosome undetermined scaffold_29, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_29, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 747
Score = 95.1 bits (226), Expect = 1e-17
Identities = 62/206 (30%), Positives = 106/206 (51%), Gaps = 16/206 (7%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
M K GDDLRQ+ L++QVI+ M ++ A L+L + ++ + S + G++E V ++
Sbjct: 492 MVKGGDDLRQELLIMQVIQKMHEIFRSAQLNLFLKPYEIIVVSENSGILEFVQNTVSMDG 551
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPS-ELEYQRARDNFTASCAGYSVATYLLGICDRHND 1289
++ + DK + + + +Y +A+ NF S AGYS+ +Y L I DRHN
Sbjct: 552 LK-------KYLDKQKLSLVQFYKQYFDSDYHQAQKNFVESLAGYSLLSYFLQIKDRHNG 604
Query: 1290 NIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQ 1349
NI++ GHL HIDFG L + GN + APF +T D + +++ + + F+
Sbjct: 605 NILVDNQGHLIHIDFGFALSISP--GN----AGFETAPFKMTKDYLEIMD--NKNSSMFE 656
Query: 1350 HFVELCCMAFNIVRAHHDHILDLFAL 1375
+F L F +R + I + +
Sbjct: 657 YFRRLMFSGFMEIRKYCASIFQIIEI 682
>UniRef50_Q6CFY9 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 960
Score = 93.9 bits (223), Expect = 3e-17
Identities = 67/221 (30%), Positives = 107/221 (48%), Gaps = 21/221 (9%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K G+DLRQ+A Q+I+ M +W A + + + L TS++ G+IE + ++ +I+
Sbjct: 687 KTGNDLRQEAFACQLIQAMKRIWDDAETGVWVKEMKILITSDTSGLIETINNGLSIHSIK 746
Query: 1233 TEWGLTGSFKDKPIAEWLAKHNPSELEY-------------QRARDNFTASCAGYSVATY 1279
+ + + K+ P+ EY Q + + F S A YS+ Y
Sbjct: 747 KALETSNVVQTTAATQTTTKYVPTLTEYWKQTFGDEDSDRYQNSLNAFVRSLAAYSIICY 806
Query: 1280 LLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVIN 1339
+L I DRHN NI+L T GH+ HIDFG M N V ++ APF LT++ V ++
Sbjct: 807 ILQIKDRHNGNILLDTDGHIMHIDFG------FMLSNSPGGVGLEAAPFKLTYEYVELMG 860
Query: 1340 GGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
G P F+ + +L AF +R + I+ L + DS
Sbjct: 861 GMTSP--HFELYRQLMKDAFKNLRKQAESIILLVDMMLQDS 899
>UniRef50_Q4N7K0 Cluster: Phosphatidylinositol 4-kinase, putative;
n=3; Eukaryota|Rep: Phosphatidylinositol 4-kinase,
putative - Theileria parva
Length = 1070
Score = 93.5 bits (222), Expect = 4e-17
Identities = 65/201 (32%), Positives = 102/201 (50%), Gaps = 17/201 (8%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+ K DDLRQ+ + QV++ ++ KA L L + + L T ++ G++E + + ++
Sbjct: 816 VIKGNDDLRQEKMANQVLESFRRIFAKANLPLWLRPIEILVTGSNSGIMEFLHDTYSVDV 875
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
I+ ++ P+ E L N E AR NF S A YS+ +YLL + DRHN N
Sbjct: 876 IKRKFNAESL---APVFEKLFYSNIYE-----ARKNFIESHAAYSIVSYLLQVKDRHNGN 927
Query: 1291 IMLKTSGHLFHIDFGKFLGDAQMFGNFK-RLVYIDRAPFVLTHDMVYVINGGERPTQRFQ 1349
I+L GH+ HID+G L NF +L+ + +PF LT + + VI GG + F
Sbjct: 928 ILLDPYGHVIHIDYGFCL------SNFPGKLISFETSPFKLTKEYLDVIEGGN--SDNFV 979
Query: 1350 HFVELCCMAFNIVRAHHDHIL 1370
+F L VR H D ++
Sbjct: 980 YFKTLITKGLLEVRKHVDEVV 1000
>UniRef50_A0DG06 Cluster: Chromosome undetermined scaffold_5, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_5, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 823
Score = 93.5 bits (222), Expect = 4e-17
Identities = 66/215 (30%), Positives = 110/215 (51%), Gaps = 21/215 (9%)
Query: 1169 PAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETL 1228
P + K GDDLRQ+ + +Q+I M + GLD+ + ++ + S S G++E A+T+
Sbjct: 569 PIIVKGGDDLRQELMTMQIIYKMYQAFQSHGLDMYVKAYEIIVVSASSGILEFC--ADTI 626
Query: 1229 RAIQTEWGLTGSFKDKPIAEWLAKHNPSEL---EYQRARDNFTASCAGYSVATYLLGICD 1285
+ G K P + L H E+ +++ A+ F S A YS+ +YLL I D
Sbjct: 627 -------SIDGLKKKYPACKSLV-HIYKEIFQQDFEEAQMRFIQSLASYSIISYLLQIKD 678
Query: 1286 RHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPT 1345
RHN NI++ + G + HIDFG L + GN ++APF LT + + ++NG R +
Sbjct: 679 RHNGNILIDSKGRIVHIDFGFILCTSP--GNLN----FEKAPFKLTQEYIDLMNG--RNS 730
Query: 1346 QRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
F ++ L F ++ + D I+ + + DS
Sbjct: 731 DLFLYYKNLMYRGFKALQGYVDEIIMIIEIMMQDS 765
>UniRef50_Q8I406 Cluster: Phosphatidylinositol 4-kinase, putative;
n=2; Eukaryota|Rep: Phosphatidylinositol 4-kinase,
putative - Plasmodium falciparum (isolate 3D7)
Length = 1559
Score = 93.1 bits (221), Expect = 5e-17
Identities = 62/200 (31%), Positives = 107/200 (53%), Gaps = 16/200 (8%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+ K GDDLRQ+ L Q+IK ++ AGL L + ++ L T ++ G+IE V + ++ +
Sbjct: 1306 IIKGGDDLRQELLASQLIKQFKIIFENAGLPLWLRPYEILVTGSNSGIIEYVNDTCSVDS 1365
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
++ ++G I S+ ++ A+ NF S A YS+ +YLL + DRHN N
Sbjct: 1366 LKRKFGADSISTIFNIVF-------SDYIFE-AKKNFIESHAAYSLISYLLQVKDRHNGN 1417
Query: 1291 IMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQH 1350
++L + GHL HID+G L ++ GN V + +PF LT + + +++G + +++
Sbjct: 1418 LLLDSDGHLIHIDYGFMLTNSP--GN----VNFETSPFKLTQEYLDIMDG--EKSDNYEY 1469
Query: 1351 FVELCCMAFNIVRAHHDHIL 1370
F L F R H + I+
Sbjct: 1470 FRRLIVSGFLEARKHSEEII 1489
>UniRef50_Q54LR9 Cluster: Phosphatidylinositol 4-kinase; n=1;
Dictyostelium discoideum AX4|Rep: Phosphatidylinositol
4-kinase - Dictyostelium discoideum AX4
Length = 1167
Score = 93.1 bits (221), Expect = 5e-17
Identities = 60/201 (29%), Positives = 104/201 (51%), Gaps = 11/201 (5%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
+I + K GDDLRQ+ +Q+I ++ + L L + + + T + G+IE V +
Sbjct: 903 LISFIVKSGDDLRQEQFAMQLITQFHRIFKQCRLPLWLRPYLVIATGHDSGLIETVPDTI 962
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286
+L ++ + + D I + ++ S + +A+ F S AGYS+ Y L I DR
Sbjct: 963 SLDNLKKKDTAFTTLLDYYIRCYGDVNSKS---FAKAQACFIESLAGYSLVCYFLQIKDR 1019
Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346
HN NI++ T GHL HID+G + NF ++APF LT + + ++ G E +
Sbjct: 1020 HNGNILIDTRGHLIHIDYGFIFSTSPGSMNF------EKAPFKLTKEFIDLMGGVE--SD 1071
Query: 1347 RFQHFVELCCMAFNIVRAHHD 1367
RF++F +L F ++ H++
Sbjct: 1072 RFEYFTKLLVAGFVEIKKHYE 1092
>UniRef50_Q10366 Cluster: Uncharacterized PI3/PI4-kinase family
protein C22E12.16c; n=1; Schizosaccharomyces pombe|Rep:
Uncharacterized PI3/PI4-kinase family protein C22E12.16c
- Schizosaccharomyces pombe (Fission yeast)
Length = 851
Score = 93.1 bits (221), Expect = 5e-17
Identities = 65/219 (29%), Positives = 109/219 (49%), Gaps = 29/219 (13%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ + K G DLRQ+ Q+I +WL+ + + + L T ++ G+IE +T A
Sbjct: 578 LVSVIVKTGADLRQETFACQLIYAFQRVWLECKEKVWVRRMKILVTGDNSGLIETITNAI 637
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEW-LAKHN--------------PSELEYQRARDNFTASC 1271
++ +I+ LT ++ +A+ +A N P+ Y++A+ NF S
Sbjct: 638 SVHSIKKN--LTKQLREAELAQGKIAGKNVVTLKDYFIKQFGDPNSSRYRQAQTNFLQSL 695
Query: 1272 AGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLT 1331
YS+ +YLL + DRHN N+++ + GH+ HIDFG L + GN V + APF LT
Sbjct: 696 VAYSIISYLLQLKDRHNGNVLIDSEGHIIHIDFGFLLTNTP--GN----VGFESAPFKLT 749
Query: 1332 HDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHIL 1370
D + +++ RF + L AF VR + D I+
Sbjct: 750 ADYLEILD------DRFDEYRSLMKAAFKSVRKNADQII 782
>UniRef50_UPI0001509F2E Cluster: Phosphatidylinositol 3- and 4-kinase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3- and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 768
Score = 92.3 bits (219), Expect = 9e-17
Identities = 65/213 (30%), Positives = 108/213 (50%), Gaps = 21/213 (9%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK GDDLRQ+ L +Q+I +++ AGL L + ++ L S S G++E + + ++ A
Sbjct: 494 IFKGGDDLRQEILAMQLIYKFQKIFMDAGLKLWLRPYEILVLSASSGILEFLPDTLSIDA 553
Query: 1231 IQTEW-GLTG--SFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287
++ + G T F ++ + A+ NF S AGYS+ +YLL DRH
Sbjct: 554 LKKKVDGFTNLYDFYQDTFGDY----------FDEAQKNFIESLAGYSIVSYLLQFKDRH 603
Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
N NI++ G L HIDFG + GN + APF LT + V ++ GG++ Q
Sbjct: 604 NGNILINNEGRLIHIDFGFMFSISP--GNMN----WENAPFKLTKEYVQLM-GGQQSDQ- 655
Query: 1348 FQHFVELCCMAFNIVRAHHDHILDLFALPSCDS 1380
+ ++ +L M F + + I+ + + DS
Sbjct: 656 YSYYKDLLFMGFQAILEKVEDIIFMVQIMQEDS 688
>UniRef50_Q5CWX0 Cluster: Membrane associated protein with 2
transmembrane domains at the N- terminus and a
phosphatidylinositol 4-kinase domain at the C-terminus;
n=3; Cryptosporidium|Rep: Membrane associated protein
with 2 transmembrane domains at the N- terminus and a
phosphatidylinositol 4-kinase domain at the C-terminus -
Cryptosporidium parvum Iowa II
Length = 2158
Score = 92.3 bits (219), Expect = 9e-17
Identities = 67/219 (30%), Positives = 111/219 (50%), Gaps = 25/219 (11%)
Query: 1168 IPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPT-----SNSK---GMI 1219
I + K DD RQD + +Q I + ++ + + + ++ LP +NS G+I
Sbjct: 1887 INLIVKCNDDCRQDVITMQYIHVFQKIFELYNIPVWLYPYRILPMMFKDINNSVIYGGII 1946
Query: 1220 EIVTEAETLRAIQ---TEWGLTGSFKDK---PIAEWLAKHNPSELEYQRARDNFTASCAG 1273
E + E+ +L I +E GL ++ + N + + Y++AR NF +S AG
Sbjct: 1947 EFIEESISLHEIHELHSEGGLKAYYESTFGGKNSHIKRLENDNSVSYEQARYNFISSLAG 2006
Query: 1274 YSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHD 1333
YS+A Y+L I DRHN NI++ +GH+ HID+G F+ D N ++ +RA F +T +
Sbjct: 2007 YSIACYVLQIKDRHNGNILITKNGHIIHIDYG-FIFDISPGNN----LHFERAAFKVTQE 2061
Query: 1334 MVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDL 1372
M+ ++ + F +LC F VR H D +L L
Sbjct: 2062 MLDFMD------DQVDLFDDLCLSGFLAVREHADLLLSL 2094
>UniRef50_A5KB26 Cluster: Phosphatidylinositol 4-kinase, putative;
n=1; Plasmodium vivax|Rep: Phosphatidylinositol 4-kinase,
putative - Plasmodium vivax
Length = 1525
Score = 91.9 bits (218), Expect = 1e-16
Identities = 60/200 (30%), Positives = 108/200 (54%), Gaps = 20/200 (10%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDLRQ+ L Q+I+ ++ AGL L + ++ L T + G+IE V + ++ +++
Sbjct: 1274 KGGDDLRQELLASQLIRQFKIIFENAGLPLWLRPYEILVTGANSGIIEYVNDTCSVDSLK 1333
Query: 1233 TEWGL--TGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
++G + + A+++ + A+ NF S A YS+ +YLL + DRHN N
Sbjct: 1334 RKFGADSISTIFNVVFADYIFE----------AKKNFIESHAAYSLVSYLLQVKDRHNGN 1383
Query: 1291 IMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQH 1350
++L + GHL HID+G L ++ GN V + +PF LT + + +++G ++ +++
Sbjct: 1384 LLLDSDGHLIHIDYGFMLTNSP--GN----VNFETSPFKLTQEYLDIMDG--EKSENYEY 1435
Query: 1351 FVELCCMAFNIVRAHHDHIL 1370
F L F R H + I+
Sbjct: 1436 FRRLIVSGFLEARKHSEEII 1455
>UniRef50_Q7RHE8 Cluster: Phosphatidylinositol 4-kinase-related; n=13;
Apicomplexa|Rep: Phosphatidylinositol 4-kinase-related -
Plasmodium yoelii yoelii
Length = 1654
Score = 91.5 bits (217), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 18/204 (8%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GDDLRQ+ L Q+IK ++ AGL L + ++ L T ++ G+IE V + ++ +++
Sbjct: 1390 KGGDDLRQELLASQLIKQFKIIFDNAGLPLWLRPYEILVTGSNSGIIEFVHDTCSVDSLK 1449
Query: 1233 TEWGLTGSFKDKPIAEWLAKHNPSELEYQ-RARDNFTASCAGYSVATYLLGICDRHNDNI 1291
++G T S N +Y A+ NF S A YS+ +YLL + DRHN N+
Sbjct: 1450 RKFG-TDSIS--------TIFNIVFADYIFEAKKNFIESHAAYSLISYLLQVKDRHNGNM 1500
Query: 1292 MLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHF 1351
+L + GHL HID+G L ++ GN V + +PF LT + + +++G + +++F
Sbjct: 1501 LLDSYGHLIHIDYGFMLTNSP--GN----VNFETSPFKLTQEYLDIMDG--ENSDNYEYF 1552
Query: 1352 VELCCMAFNIVRAHHDHILDLFAL 1375
L F R H + I+ L L
Sbjct: 1553 RRLIVSGFLEARKHSEEIILLVEL 1576
>UniRef50_A0C4X5 Cluster: Chromosome undetermined scaffold_15, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_15, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 688
Score = 91.5 bits (217), Expect = 2e-16
Identities = 59/204 (28%), Positives = 104/204 (50%), Gaps = 15/204 (7%)
Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
++ + K GDDLRQ+ +Q+I D ++ L L++ T++ + G+IE+V +A
Sbjct: 432 LVHLIVKSGDDLRQEQFAMQLISTFDQIFKIEQLKLQLTTYEVISLGPGYGLIEVVKDAL 491
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286
++ +I+ + L + K ++ + ++ Q NF S YS+ Y L I DR
Sbjct: 492 SIDSIKKK--LNDILQIKCLSSYFNLNSS-----QAMISNFLNSLVAYSLVCYFLQIKDR 544
Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346
HN NI+L G++ H+DFG FL A G+ ++ V PF LT + + ++ G +
Sbjct: 545 HNGNILLHRDGYIVHVDFGFFLSHAPK-GSLEKDV-----PFKLTEEYMQILGGYN--SN 596
Query: 1347 RFQHFVELCCMAFNIVRAHHDHIL 1370
F+ F ++ F +R H D I+
Sbjct: 597 LFKRFRKMFFEGFKAIRKHKDKIM 620
>UniRef50_A4QPH2 Cluster: LOC375133 protein; n=8; Eutheria|Rep:
LOC375133 protein - Homo sapiens (Human)
Length = 597
Score = 89.0 bits (211), Expect = 9e-16
Identities = 60/181 (33%), Positives = 94/181 (51%), Gaps = 16/181 (8%)
Query: 1180 QDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAI--QTEWGL 1237
QD L LQ+I + ++ GLDL + ++ + T+ G+IE + + + + QT++G+
Sbjct: 344 QDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGM 403
Query: 1238 TGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSG 1297
F + E S L +Q+A NF S A YS+ +LL I DRHN NIML G
Sbjct: 404 YDYFTRQYGDE-------STLAFQQACYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKG 456
Query: 1298 HLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCM 1357
H+ HIDFG F+ ++ GN + P + D + +I GG+ F+ F+E+C
Sbjct: 457 HIIHIDFG-FMFESSPGGN------LGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVQ 509
Query: 1358 A 1358
A
Sbjct: 510 A 510
>UniRef50_Q57WD8 Cluster: Phosphatidylinositol 4-kinase alpha,
putative; n=1; Trypanosoma brucei|Rep:
Phosphatidylinositol 4-kinase alpha, putative -
Trypanosoma brucei
Length = 2312
Score = 87.4 bits (207), Expect = 3e-15
Identities = 59/178 (33%), Positives = 93/178 (52%), Gaps = 18/178 (10%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FK+GDD RQD L LQ+I + ++ L + ++ + T G+IE V A +
Sbjct: 2039 IFKMGDDCRQDQLALQLIGLFRRVFDSIQLPSFLYPYKVVATGRDCGVIECVPRAMSRDQ 2098
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHN--PSELEYQRARDNFTASCAGYSVATYLLGICDRHN 1288
I G + ++E+ + P + + RAR+ F S A Y+ A+++L I DRHN
Sbjct: 2099 I-------GKLVEGNLSEYFVQTYGYPESVRFHRARECFIRSMASYATASFVLNIKDRHN 2151
Query: 1289 DNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV----YVINGGE 1342
NI++ + GHL HIDFG FL D G+ + + +PF LT +M Y +N G+
Sbjct: 2152 GNILIDSYGHLVHIDFG-FLFDLSPGGD----INFESSPFKLTLEMAQLMGYPVNEGK 2204
>UniRef50_Q4U9S5 Cluster: Phosphatidylinositol 4-kinase, putative;
n=2; Theileria|Rep: Phosphatidylinositol 4-kinase,
putative - Theileria annulata
Length = 1194
Score = 86.6 bits (205), Expect = 5e-15
Identities = 69/247 (27%), Positives = 119/247 (48%), Gaps = 28/247 (11%)
Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQA 1209
S+ P +++ +D + ++K+ DDLRQD L +Q+ + + ++ L + + F
Sbjct: 893 SATRAPFMVSYKLSDGSERTYIYKMKDDLRQDCLAIQMKQFLLQIFYNHELFVYLRPFLV 952
Query: 1210 LPTSN------SKGMIEIVTEAETLRAIQTE-WGLTGSFKDK------------PIAEWL 1250
+P S S I ++ + + +E G+ G D PI ++
Sbjct: 953 IPYSGILFEIFSDSKINDISLSNYYNSKFSEIGGVVGFIPDTISRHHIGKEFGVPIKDFF 1012
Query: 1251 AKHNPSELE--YQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFL 1308
K + Y +A DNF S AGY++ ++LL + DRHN N++ TSGH+ HIDFG L
Sbjct: 1013 LKRFGHQFSPNYIKAVDNFITSLAGYALLSFLLQVKDRHNGNLLFTTSGHIIHIDFGFIL 1072
Query: 1309 GDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDH 1368
G + K L + + APF T +MV + G + + F+ F+ L ++ +R H +
Sbjct: 1073 GASPA----KDLQF-ELAPFKFTPEMVDFMGGSK--SDNFKRFIHLLLNSYMALRTHSNL 1125
Query: 1369 ILDLFAL 1375
I+ L L
Sbjct: 1126 IITLVKL 1132
>UniRef50_A7ARY7 Cluster: Phosphatidylinositol 4 kinase, putative;
n=1; Babesia bovis|Rep: Phosphatidylinositol 4 kinase,
putative - Babesia bovis
Length = 1143
Score = 84.6 bits (200), Expect = 2e-14
Identities = 63/200 (31%), Positives = 103/200 (51%), Gaps = 16/200 (8%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+ K GDDLRQ+ +V Q++ + ++ A L L + + L T + G+IE + + ++
Sbjct: 890 IIKGGDDLRQEYMVNQLLLLFKEIFANAHLPLWIRPVEILVTGPNCGIIEFLHDTCSVDV 949
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
++ ++ + IA + + Y+ AR NF S A YS+ +YLL + DRHN N
Sbjct: 950 VKRKFNVDS------IARAFERMYAKTI-YE-ARKNFIESHAAYSIISYLLQVRDRHNGN 1001
Query: 1291 IMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQH 1350
I+L + GH+ HID+G L + GN + + +PF LT + V V+ GGE + F +
Sbjct: 1002 ILLDSDGHVIHIDYGFCLSNTP--GN----ISFETSPFKLTKEYVDVM-GGE-TSDNFGY 1053
Query: 1351 FVELCCMAFNIVRAHHDHIL 1370
F L R H D I+
Sbjct: 1054 FKALVIRGLLEARKHMDRIV 1073
>UniRef50_A0E590 Cluster: Chromosome undetermined scaffold_79, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_79, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 752
Score = 84.2 bits (199), Expect = 2e-14
Identities = 62/197 (31%), Positives = 100/197 (50%), Gaps = 18/197 (9%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+ K GDDLRQ+ +++Q+IK+ + + + GL ++ ++ + TS G++E + TL
Sbjct: 503 LIKGGDDLRQEQMMMQIIKVSEDILTQVGLYVK--SYDIIITSVDSGILEFCND--TLSM 558
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
Q + + S K I + N ++ A+ NF S YS+ YL I DRHN N
Sbjct: 559 DQLKKSMP-SMTLKDIYNSIFGDN-----FEEAQLNFILSLTSYSLLQYLFQIKDRHNGN 612
Query: 1291 IMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQH 1350
I++ GH+ HIDFG L A G K + APF LT + + +++G E + FQ
Sbjct: 613 ILIDNQGHIIHIDFGFILTIAP--GGIK----FESAPFKLTKEYIELLDGQE--SCMFQL 664
Query: 1351 FVELCCMAFNIVRAHHD 1367
F + + +R H D
Sbjct: 665 FKSKLLLGYLELRKHVD 681
>UniRef50_Q8SS90 Cluster: PHOSPHATIDYLINOSITOL-4-KINASE CATALYTIC
SUBUNIT; n=1; Encephalitozoon cuniculi|Rep:
PHOSPHATIDYLINOSITOL-4-KINASE CATALYTIC SUBUNIT -
Encephalitozoon cuniculi
Length = 711
Score = 83.8 bits (198), Expect = 3e-14
Identities = 43/138 (31%), Positives = 75/138 (54%), Gaps = 3/138 (2%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K G+ L Q+ + QV+ M +W + G + + +Q S++ G++E V +A ++ I+
Sbjct: 460 KTGNSLMQELMAYQVLCEMKRIWREEGSPIWIRAYQIYLISDTSGIVETVVDAMSIHKIK 519
Query: 1233 TEWGLTGSFKDKPIAEWLA-KHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNI 1291
+ + K+ + + A + +Y+ NF S GYS+ATY+L + DRHN NI
Sbjct: 520 KK--MMSENKNYSLRNYFADSFELNSAKYKSCLRNFLYSLVGYSLATYILQVKDRHNGNI 577
Query: 1292 MLKTSGHLFHIDFGKFLG 1309
M+ GH+ H+DFG +G
Sbjct: 578 MIDGQGHIVHVDFGFVMG 595
>UniRef50_Q23R89 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 894
Score = 82.2 bits (194), Expect = 1e-13
Identities = 64/217 (29%), Positives = 104/217 (47%), Gaps = 12/217 (5%)
Query: 1173 KVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ 1232
K GD+L+Q+ Q+I D ++ + L+L + ++ + + G+IE+V + T ++
Sbjct: 623 KTGDNLKQEQFAQQLIYQFDQIFKDSELNLILRPYEIISLGPNCGIIEVVKNSVTFDSLI 682
Query: 1233 TEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIM 1292
+ L K + E+ + S L +A+ NF +S A YS+ Y L I DRHN NI+
Sbjct: 683 QK--LNTQQKGMNLQEFFKSYYGSGL--YKAQKNFCSSLAAYSLVCYFLQIKDRHNGNIL 738
Query: 1293 LKTSGHLFHIDFGKFLGDAQ-----MFGNFKRLVYID-RAPFVLTHDMVYVINGGERPTQ 1346
L G++ HIDFG L +A N ++ V + PF L D + V+ G +
Sbjct: 739 LHKDGYICHIDFGFLLSNAPGNNLIQKNNQRQGVGFELNVPFKLLTDYINVLGGVN--SD 796
Query: 1347 RFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSGGS 1383
F+ F +L F R + D IL L + G S
Sbjct: 797 LFKQFRQLFHKGFMAARKNQDKILILVKMFYSSHGAS 833
>UniRef50_Q8SR56 Cluster: PHOSPHATIDYL INOSITOL-3-KINASE; n=1;
Encephalitozoon cuniculi|Rep: PHOSPHATIDYL
INOSITOL-3-KINASE - Encephalitozoon cuniculi
Length = 458
Score = 81.8 bits (193), Expect = 1e-13
Identities = 54/161 (33%), Positives = 84/161 (52%), Gaps = 15/161 (9%)
Query: 1149 FSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQ 1208
F S+T P+ + + TD V ++K GDDL +D VL+ I+ M L G+DL VT++
Sbjct: 196 FPSSTFPILVP-LRTDRGVSRIIYKKGDDLTRDLFVLETIRYMSRLM---GVDL--VTYK 249
Query: 1209 ALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFT 1268
+P S +G++E+V + R I++ L ++ +P E R F
Sbjct: 250 VIPLSRKEGIVEVVDGIDFTR-IRSRKDLEMYIEED--------RDPRHQESFEKRKVFV 300
Query: 1269 ASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLG 1309
++ GYSVA Y++GI DR+ N+M+ G FHIDF G
Sbjct: 301 STLCGYSVACYVMGIGDRNPGNMMVTRDGKFFHIDFSHVFG 341
>UniRef50_A0ED64 Cluster: Chromosome undetermined scaffold_9, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_9, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 703
Score = 81.0 bits (191), Expect = 2e-13
Identities = 57/209 (27%), Positives = 101/209 (48%), Gaps = 10/209 (4%)
Query: 1169 PAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMI--EIVTEAE 1226
P + K GDDLRQ+ +Q++K + ++ +A ++L + +Q + TS + G++ E
Sbjct: 440 PIIIKGGDDLRQEMFAIQIMKQFNKIFKEAEVNLYLRPYQIIVTSANSGIVGNSYCYHQE 499
Query: 1227 TLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDR 1286
+ + L F + + ++ A+ NF S A YSV +YL+ + DR
Sbjct: 500 YIPNTISIDALKKMFGNGTKTLYQIYQEIFGSAFEEAQKNFIESLASYSVFSYLMQVKDR 559
Query: 1287 HNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQ 1346
HN N+++ GH+ HIDFG L + NF + APF LT + + ++ G E +
Sbjct: 560 HNGNLLIDDRGHVIHIDFGFLLQTSPGGVNF------ESAPFKLTQEYLELMMGKE--SD 611
Query: 1347 RFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
F +F L F ++ + I + F +
Sbjct: 612 YFGYFKSLMTKGFLALKKYVIEIENFFKI 640
>UniRef50_Q5UR69 Cluster: Putative uncharacterized protein; n=1;
Acanthamoeba polyphaga mimivirus|Rep: Putative
uncharacterized protein - Mimivirus
Length = 701
Score = 79.8 bits (188), Expect = 5e-13
Identities = 64/218 (29%), Positives = 112/218 (51%), Gaps = 23/218 (10%)
Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLK-AGLDLRMVTFQ 1208
+S T P+ I F T+ I +FK + + D +V+ +I + D + + GL+L +V +
Sbjct: 415 NSYTRPVIIAF-ETNVGRIDILFKK-ESVMNDLIVMNLISLCDVIIKENIGLELGIVVYP 472
Query: 1209 ALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFT 1268
+P +N+ GMIEI+ AET+ +I + K + + + N +++ +
Sbjct: 473 IMPLTNNFGMIEIIKNAETIHSIINQ--------KKTVFQHIIDKNENKV-ISDIMKTYM 523
Query: 1269 ASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAP 1327
S Y++ +Y +G+ DRH +NIM+ +G +FHIDFG LG DA F + D
Sbjct: 524 YSLVSYTLHSYFIGLGDRHLENIMITDNGEIFHIDFGFILGTDA-----FPLTLTSD--- 575
Query: 1328 FVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAH 1365
L M+ VI G R + R++ +++LC I+R +
Sbjct: 576 IKLNSGMLDVIGG--RGSDRYKIYLDLCAKGVIILRKY 611
>UniRef50_Q7R239 Cluster: GLP_630_45311_38844; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_630_45311_38844 - Giardia lamblia
ATCC 50803
Length = 2155
Score = 79.8 bits (188), Expect = 5e-13
Identities = 46/128 (35%), Positives = 68/128 (53%), Gaps = 8/128 (6%)
Query: 1250 LAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLG 1309
+ KH + Y + N+ S A Y VAT +LG+ DRHNDNIML G FHIDFG FLG
Sbjct: 1964 IQKHTATR--YTQMISNYLTSIAAYCVATCILGLGDRHNDNIMLCQDGTFFHIDFGHFLG 2021
Query: 1310 DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGE--RPTQRFQHFVELCCMAFNIVRAHHD 1367
+ + N++R +R PF DM +V+ + T+ + F ++ A +R H
Sbjct: 2022 NFKKKFNYER----ERGPFFFIPDMAFVLKHHDYVNGTEYEKCFEKMSADALLAIRHHSS 2077
Query: 1368 HILDLFAL 1375
++ LF +
Sbjct: 2078 ALISLFTI 2085
Score = 76.2 bits (179), Expect = 7e-12
Identities = 46/140 (32%), Positives = 71/140 (50%), Gaps = 3/140 (2%)
Query: 1130 LPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAV-IPAMFKVGDDLRQDALVLQVI 1188
LPL+ + V C SS PL ++ D A +FK DDLRQD+LVL+
Sbjct: 1738 LPLSYDIKLATFCVVECAVLSSKKAPLLLSLKTADGAFNYKCLFKTHDDLRQDSLVLRTF 1797
Query: 1189 KIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQ-TEWGLTGSFKDKPIA 1247
+ +W ++L M + + T +G+IE+V ++ETL +I+ T G G+F PI
Sbjct: 1798 SYIQNVWYNNNINLAMKVYSCVATGPFEGLIELVPDSETLGSIEHTFGGARGAFARGPIM 1857
Query: 1248 EWLAKH-NPSELEYQRARDN 1266
+WL N + E+ R + N
Sbjct: 1858 KWLVDSINLHDEEFLRVQKN 1877
>UniRef50_A7ATH3 Cluster: 1-phosphatidylinositol 4-kinase, putative;
n=1; Babesia bovis|Rep: 1-phosphatidylinositol 4-kinase,
putative - Babesia bovis
Length = 1220
Score = 79.8 bits (188), Expect = 5e-13
Identities = 50/160 (31%), Positives = 83/160 (51%), Gaps = 14/160 (8%)
Query: 1217 GMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNP-SELEYQRARDNFTASCAGYS 1275
G++ + + + I ++G GS +D +L K P ++ A DNF S AGYS
Sbjct: 1012 GIVGFIPGSISRHTIGQDYG--GSLEDY----FLLKFGPRGSTTFRCAMDNFIKSMAGYS 1065
Query: 1276 VATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+ +LL + DRHN N+M+ ++GH+ HID+G LG + V+ ++APF LT +M
Sbjct: 1066 LLCFLLQVKDRHNGNLMISSAGHIIHIDYGFILGSSPAAD-----VHFEQAPFKLTKEMT 1120
Query: 1336 YVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
++ G E + FQ +V L ++ VR ++ L
Sbjct: 1121 DLLGGVE--SDNFQRYVRLLVASYLCVRQESSTLISFVKL 1158
Score = 40.7 bits (91), Expect = 0.30
Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 1136 KYVHDLDVKSCTYFSSNT-LPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTL 1194
K + LD K+ +S T +P ++F ++ ++K+ DD+RQDALV+QV + +
Sbjct: 808 KSIRCLDAKTSHMLNSATRVPFTLDFYLENSMSTRYIYKMNDDMRQDALVIQVKLFLMHV 867
Query: 1195 WLKAGLDLRMVTFQALPTSNS 1215
+ K L+ + F +P S +
Sbjct: 868 FRKYNLEAYLQPFLVVPYSTA 888
>UniRef50_Q7QSW7 Cluster: GLP_44_18876_25655; n=2; Giardia
intestinalis|Rep: GLP_44_18876_25655 - Giardia lamblia
ATCC 50803
Length = 2259
Score = 79.0 bits (186), Expect = 9e-13
Identities = 64/193 (33%), Positives = 90/193 (46%), Gaps = 16/193 (8%)
Query: 1166 AVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEA 1225
AV +FK GDD+ QD L + +I + ++ L + + + ALP G IE++ +A
Sbjct: 1990 AVKGGIFKAGDDVSQDQLTMVLISLFKQVF--EPLKMWLSPYIALPIGKDYGFIELLNKA 2047
Query: 1226 ETLRAIQTEW-----GLTGSFKDKPIAEWLAK-HNPSELEYQRARDNFTASCAGYSVATY 1279
+L I G S + E H +L A+ F S AGYS+ +Y
Sbjct: 2048 SSLDQIGATSDNFLVGYISSITEASREEATGTPHASQKLSLTVAKRRFLLSYAGYSILSY 2107
Query: 1280 LLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVIN 1339
LL DRHN NIM+ ++ HIDFG FL + G F + APF LT ++
Sbjct: 2108 LLSFKDRHNGNIMINEYCNVIHIDFG-FLLEIAPGGKFN----TESAPFKLTKAFKTIL- 2161
Query: 1340 GGERPTQ--RFQH 1350
GGE T FQH
Sbjct: 2162 GGEESTSYTLFQH 2174
>UniRef50_A0BVP3 Cluster: Chromosome undetermined scaffold_130, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_130, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 608
Score = 79.0 bits (186), Expect = 9e-13
Identities = 42/135 (31%), Positives = 74/135 (54%), Gaps = 9/135 (6%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+ K GDDLR + L++Q+IK + ++ K LD+ + + + TS + G++E + ++
Sbjct: 355 IIKGGDDLRNELLIMQMIKKIKEIFEKHKLDIFLRPYDIILTSPNSGILEFIPNTVSIDK 414
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
I+ + ++D + ++ + A+ NF S AGYS+ YL + DRHN N
Sbjct: 415 IKRD------YQDYTLKQFYENFFDC---FSEAQTNFLQSLAGYSLICYLFQLKDRHNGN 465
Query: 1291 IMLKTSGHLFHIDFG 1305
I++ GH+ HIDFG
Sbjct: 466 ILIDNQGHIIHIDFG 480
>UniRef50_Q6C0Z0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 1845
Score = 77.8 bits (183), Expect = 2e-12
Identities = 68/244 (27%), Positives = 111/244 (45%), Gaps = 40/244 (16%)
Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSN 1214
P KI +G+D P + K DD+R+DA +L++ +++D L K L ++ T+ P +
Sbjct: 1528 PFKITLVGSDGKDYPVLLKNKDDVRKDARLLEITQLVDKLLAKNTLGIK--TYFVTPLGD 1585
Query: 1215 SKGMIEIVTEAETLRAI------QTEWG-LT-----GSFKDKP----------------I 1246
S G+IE V+ + T +++ +WG LT G+ + K +
Sbjct: 1586 SCGLIEWVSGSVTAKSVILRFYEDIDWGTLTEQLEYGASRGKKTGAKVFLKILKNYQPEL 1645
Query: 1247 AEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGK 1306
W + ++ RARD FT S A S+ Y+LG+ DRH +NI+L G + H+DF
Sbjct: 1646 YRWFLEKFSEPHKWLRARDKFTKSLAVMSIVGYVLGLGDRHLENILLLGDGGVMHVDFD- 1704
Query: 1307 FLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHH 1366
+F L + PF LT ++V + T HF C ++R H
Sbjct: 1705 -----NLFEKALSLTKPEMVPFRLTQNLVDAMG----VTGYEGHFRRSCESTLALLRQHE 1755
Query: 1367 DHIL 1370
I+
Sbjct: 1756 YTIM 1759
>UniRef50_Q5CVD3 Cluster: Phosphatidylinositol 4-kinase; n=2;
Cryptosporidium|Rep: Phosphatidylinositol 4-kinase -
Cryptosporidium parvum Iowa II
Length = 1114
Score = 76.2 bits (179), Expect = 7e-12
Identities = 55/200 (27%), Positives = 96/200 (48%), Gaps = 14/200 (7%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+ K DDLRQ+ L Q+++ D ++ L L + ++ L + G IE + + ++ +
Sbjct: 857 LLKSSDDLRQEYLASQLLQQFDWIFKINKLPLWLHPYEILVIGSHGGFIEYIQDTFSIDS 916
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
++ F+ + + E +AR F S A YS+ +Y L + DRHN N
Sbjct: 917 LKRR------FQTDNLLNCFDQLFKDEELKSKARKCFVESHAAYSLVSYFLQVKDRHNGN 970
Query: 1291 IMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQH 1350
++ GH+ ID+G L ++ GN V +++PF LT + + V+ G + FQ+
Sbjct: 971 FLIDKHGHIIQIDYGFMLSNSP--GN----VNFEQSPFKLTQEFLDVMMG--ENSSDFQY 1022
Query: 1351 FVELCCMAFNIVRAHHDHIL 1370
F +L F R H D I+
Sbjct: 1023 FQQLIIKGFLASRKHVDQIV 1042
>UniRef50_Q5KGM7 Cluster: UVSB PI-3 kinase, putative; n=2;
Filobasidiella neoformans|Rep: UVSB PI-3 kinase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 1854
Score = 74.1 bits (174), Expect = 3e-11
Identities = 60/206 (29%), Positives = 96/206 (46%), Gaps = 16/206 (7%)
Query: 1138 VHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLK 1197
+HD++ + S P K+ FIG+D P + K DDLR+DA V+ + +++ L
Sbjct: 1540 IHDVEDR-VDVMPSLQRPKKLVFIGSDGKAYPFLCKPHDDLRKDARVMDLNSMINKLLKS 1598
Query: 1198 AG----LDLRMVTFQALPTSNSKGMIEIVTEAETLRAI-QTEWGLTGSFKDKPIA--EWL 1250
A L + T+ +P + G++E VT + I +T +G K P EW
Sbjct: 1599 ASESRRRQLYVRTYAVMPLNEECGLLEWVTNTHGFKGILETNYGRQNK-KIFPTVFHEWF 1657
Query: 1251 AKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLK-TSGHLFHIDFGKFLG 1309
P + +R ++ + A S+ Y+LG+ DRH +NI+ SG H+D
Sbjct: 1658 LTSWPEPSAWLSSRLAYSRTLAVMSMIGYILGLGDRHGENILFDGLSGDTVHVDLN---- 1713
Query: 1310 DAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+F K L +R PF LT +MV
Sbjct: 1714 --CLFEKGKTLEIPERVPFRLTQNMV 1737
>UniRef50_Q5C275 Cluster: SJCHGC06440 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06440 protein - Schistosoma
japonicum (Blood fluke)
Length = 205
Score = 72.9 bits (171), Expect = 6e-11
Identities = 46/114 (40%), Positives = 61/114 (53%), Gaps = 13/114 (11%)
Query: 1265 DNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYID 1324
+ + SCAGY V TYLLG+ DRH +N++L GHLFHIDFG LG
Sbjct: 41 ETYIRSCAGYCVITYLLGVGDRHMENLLLTADGHLFHIDFGFILGSDPK----------P 90
Query: 1325 RAPFV-LTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPS 1377
AP V LT M+ + G + +F F ++ AF I+R H + L LF+L S
Sbjct: 91 MAPEVRLTRAMIDGMGGPN--SNQFNEFWKITFTAFLILRRHANLFLTLFSLMS 142
>UniRef50_Q54UU9 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1229
Score = 70.9 bits (166), Expect = 2e-10
Identities = 50/162 (30%), Positives = 82/162 (50%), Gaps = 29/162 (17%)
Query: 1176 DDLRQDALVLQVIKIMDTLWLKAGLDLRM-----------------VTFQALPTSNSKGM 1218
DDLR+D ++L +I +M+ L ++ +LR + ++ LPT + G
Sbjct: 836 DDLRKDQIILNLIYLMNELIIQCN-ELRKLKESSGKKKHKEPFMQPIVYRVLPTGVNYGF 894
Query: 1219 IEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVAT 1278
IE V +++TL+ + E+ SF + L Y +A NF+ S A +++ T
Sbjct: 895 IEPVKKSKTLKDVLVEYNRITSFLG----------SSQTLTYDQASKNFSRSLATWNIIT 944
Query: 1279 YLLGICDRHNDNIMLKTSGHLFHIDFGKFLG-DAQMFGNFKR 1319
+LLG+ DRHN N+M +FHID+G LG D + F + R
Sbjct: 945 HLLGVGDRHNQNVMFTEEMKIFHIDYGFILGMDPKFFSSVIR 986
>UniRef50_Q00UA0 Cluster: Phosphatidylinositol 4-kinase, putative;
n=2; Ostreococcus|Rep: Phosphatidylinositol 4-kinase,
putative - Ostreococcus tauri
Length = 900
Score = 70.1 bits (164), Expect = 4e-10
Identities = 45/125 (36%), Positives = 64/125 (51%), Gaps = 9/125 (7%)
Query: 1259 EYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFK 1318
+++ A+ NF S AGYSV TYLL + DRHN NI++ GHL HIDF L + NF
Sbjct: 725 QFREAQANFVESLAGYSVLTYLLQVKDRHNGNILMHEDGHLIHIDFNFMLSTSPGGINF- 783
Query: 1319 RLVYIDRAPFVLTHDMVYVINGG--ERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALP 1376
+ APF LT + + +++ + + F + L F VR H I+ L +
Sbjct: 784 -----ESAPFKLTKEYLELMDSDIEGKNSDAFDAYKALVIHGFTAVRKHAARIVLLVQMM 838
Query: 1377 SCDSG 1381
DSG
Sbjct: 839 G-DSG 842
>UniRef50_Q6CAD2 Cluster: Serine/threonine-protein kinase TEL1; n=1;
Yarrowia lipolytica|Rep: Serine/threonine-protein kinase
TEL1 - Yarrowia lipolytica (Candida lipolytica)
Length = 2282
Score = 70.1 bits (164), Expect = 4e-10
Identities = 82/260 (31%), Positives = 121/260 (46%), Gaps = 57/260 (21%)
Query: 1155 PLKINFIGTDNAVIPAMFKVG-DDLRQDALVLQVIKIMDTLWL------KAGLDLRMVTF 1207
P ++F +D +V A+ K G DD+RQDA++ QV ++ +L K GL +R T+
Sbjct: 1952 PKIMDFQLSDGSVSKALLKGGKDDMRQDAIMEQVFCRVNQYFLGDPETRKRGLSIR--TY 2009
Query: 1208 QALPTSNSKGMIEIVTEAETLRAI------QTEWG-LTGSFKDKPIA-----------EW 1249
+P GMIE V E+L+A + +W LTG K +A E
Sbjct: 2010 NVVPMGPRAGMIEFVANTESLQAALVPLHEKDDWDYLTGRTKMSAVAKESNSRRVEVLEE 2069
Query: 1250 LAKH-NP--SELEYQ----------RARDNFTASCAGYSVATYLLGICDRHNDNIMLK-T 1295
+ H P S+ +Q +AR N+ S A S+ Y+LGI DRH +NIM+
Sbjct: 2070 IYTHVTPVMSQYFFQNFRSSAQAWFKARTNYVRSAAASSMLGYILGIGDRHCNNIMIDYK 2129
Query: 1296 SGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVIN--GGERPTQRFQHFVE 1353
+G L HID G F K L ++ PF LT DMV + G + P +R
Sbjct: 2130 TGQLVHIDLG------ISFDQGKNLTVPEKVPFRLTRDMVDAMGSVGVDGPFRR------ 2177
Query: 1354 LCC-MAFNIVRAHHDHILDL 1372
CC ++ + R D+IL +
Sbjct: 2178 -CCELSLGLFREQQDNILSI 2196
>UniRef50_A7T8E9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 321
Score = 67.3 bits (157), Expect = 3e-09
Identities = 45/106 (42%), Positives = 60/106 (56%), Gaps = 11/106 (10%)
Query: 1270 SCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFV 1329
S +GY V TYLLG+ DRH DN++L SG+LFHIDFG LG + K L P
Sbjct: 166 SVSGYCVITYLLGVGDRHLDNLLLTKSGNLFHIDFGYILG-----RDPKPL----PPPMK 216
Query: 1330 LTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
L+ +MV + G + +Q F + C AF +R H + IL+LF L
Sbjct: 217 LSKEMVEGMGGAN--GECYQAFRKQCYTAFLHLRRHANLILNLFGL 260
Score = 46.0 bits (104), Expect = 0.008
Identities = 27/70 (38%), Positives = 40/70 (57%), Gaps = 8/70 (11%)
Query: 1130 LPLALHKYVHDLDVKSCTY-------FSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDA 1182
LPL L V ++V +C + F S+ +P K+ F + +FK GDDLRQD
Sbjct: 61 LPLPLDPDVRIMEV-TCVFLSEKAWLFKSHLMPAKLTFRDINEQEYVVIFKNGDDLRQDQ 119
Query: 1183 LVLQVIKIMD 1192
L+LQ+I++MD
Sbjct: 120 LILQMIRLMD 129
>UniRef50_A3LQL4 Cluster: 1-phosphatidylinositol 3-kinase; n=2;
Saccharomycetaceae|Rep: 1-phosphatidylinositol 3-kinase -
Pichia stipitis (Yeast)
Length = 1017
Score = 66.5 bits (155), Expect = 5e-09
Identities = 42/112 (37%), Positives = 60/112 (53%), Gaps = 13/112 (11%)
Query: 1265 DNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYID 1324
DN+ SCAGY V TYLLG+ DRH DN++L +G +H DFG LG + K L +
Sbjct: 853 DNYVKSCAGYCVITYLLGVGDRHLDNLLLSPNGKFWHADFGYILG-----RDPKILPPLM 907
Query: 1325 RAPFVLTHDMVYVING-GERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+ P + VI+G G + F F C + + +R + + IL+LF L
Sbjct: 908 KLP-------IQVIDGMGGLNHENFNIFKSYCFITYTTLRKNSNLILNLFQL 952
Score = 61.7 bits (143), Expect = 1e-07
Identities = 31/63 (49%), Positives = 42/63 (66%), Gaps = 1/63 (1%)
Query: 1169 PAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETL 1228
P MFK+GDDLRQD LV+Q+I +M+ L LDLR+ ++ L TS G+I+ V ETL
Sbjct: 715 PLMFKIGDDLRQDQLVIQIINLMNQLLKNENLDLRLTPYKILATSPVAGLIQFVPN-ETL 773
Query: 1229 RAI 1231
+I
Sbjct: 774 DSI 776
>UniRef50_UPI0000F1FBED Cluster: PREDICTED: similar to
phosphoinositide-3-kinase, class 2, beta polypeptide,,
partial; n=1; Danio rerio|Rep: PREDICTED: similar to
phosphoinositide-3-kinase, class 2, beta polypeptide,,
partial - Danio rerio
Length = 374
Score = 65.3 bits (152), Expect = 1e-08
Identities = 77/359 (21%), Positives = 141/359 (39%), Gaps = 25/359 (6%)
Query: 470 SLSEYDYIRECVRLEKDVTLCL--HEGRDSTLARTERDDAKDSHLTLDDLFPAQGATPML 527
+L+ ++YI++C++ + D+ L L + LART DD S + L + +
Sbjct: 3 TLASFEYIQQCLKFDWDIRLILTKRSSVNMELARTTEDDDTPSTMNHSILLQERPIKQTV 62
Query: 528 SFDNLSILLETLEGELSRAIGVTSAEGSCSPKAVFQAVKAICALAGGVETLHVTHTLNAF 587
+ + L++LL+T E + ++ E + + Q+VKA+C VET +T LN
Sbjct: 63 TKEALTLLLDTFHNEAESFL-LSEVELPLHVERLVQSVKALCTSLAAVETPDITAALNQL 121
Query: 588 -AQACTAQGANNVVRPEIEREQGAYCSVSLAAGSRRDCVSLQGGRVR-DAVXXXXXXXXX 645
A C Q + +++ V + D V L +
Sbjct: 122 PACPCRLQPKVQKDVSVLAKKENRVAIVEKLTAAILDLVELYCSTFNANFHTMPHSSRST 181
Query: 646 XXXXDFRLADAHYQAPANPAKAVPAHTISETTLFCIE-AVHCLPL----CWSHDEYMFHA 700
+ + A VP + + + I + L L +S++ +
Sbjct: 182 APIQEAGMVTNVLSFSVYAAHRVPITWAARSNILLISPSFSALSLEQKHTYSYENFFLSC 241
Query: 701 QIYHGTRPLKTLRFTQASKIECGGFYPRIIFDTWLNLEDLPVNTLPRESRLVLTLHGRTQ 760
+ HG L + T + F+ +++D + + +N LPRES+L +TL+
Sbjct: 242 SLTHGGVELCAPQHTSKQSVSKYLFH-LVVWDQRVCF-PVQINQLPRESQLTVTLYA--- 296
Query: 761 RTIDSQHPNENSPPSSQEAEDSGDVLYEQVELGWAALQLFDFDGMLSSGNYVLPLWPTS 819
PP E + E LGW + LF+F +L+ G +L LWP++
Sbjct: 297 --------TPLPPPGGAEEKSKQKRSIE--SLGWVTMPLFNFRHVLTCGRKLLGLWPST 345
>UniRef50_Q92213 Cluster: Phosphatidylinositol 3-kinase VPS34; n=4;
Saccharomycetales|Rep: Phosphatidylinositol 3-kinase
VPS34 - Candida albicans (Yeast)
Length = 1020
Score = 65.3 bits (152), Expect = 1e-08
Identities = 40/113 (35%), Positives = 59/113 (52%), Gaps = 15/113 (13%)
Query: 1265 DNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYI 1323
DN+ SCAGY V TY+LG+ DRH DN++L +G +H DFG LG D + F +L
Sbjct: 856 DNYVKSCAGYCVITYILGVGDRHLDNLLLSPNGKFWHADFGYILGRDPKPFPPLMKL--- 912
Query: 1324 DRAPFVLTHDMVYVING-GERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL 1375
+ VI+G G + + F C + + +R + + IL+LF L
Sbjct: 913 ----------PIQVIDGMGGLHHENYNVFKSYCFITYTTLRKNSNLILNLFQL 955
Score = 62.5 bits (145), Expect = 9e-08
Identities = 31/63 (49%), Positives = 42/63 (66%), Gaps = 1/63 (1%)
Query: 1169 PAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETL 1228
P MFK+GDDLRQD LV+Q+I +MD L LDL++ ++ L TS G+I+ V ETL
Sbjct: 710 PLMFKIGDDLRQDQLVIQIIDLMDQLLKNENLDLKLTPYKILATSPISGLIQFVPN-ETL 768
Query: 1229 RAI 1231
+I
Sbjct: 769 DSI 771
>UniRef50_A2F4J8 Cluster: PIKK family atypical protein kinase; n=1;
Trichomonas vaginalis G3|Rep: PIKK family atypical
protein kinase - Trichomonas vaginalis G3
Length = 2165
Score = 63.7 bits (148), Expect = 4e-08
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 13/132 (9%)
Query: 1259 EYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNF 1317
E+ R +DNFT + A S+ Y++G+ DRH NIM+ + +G + HIDFG
Sbjct: 1986 EWLRMQDNFTLTTALMSMIGYVIGLGDRHPSNIMVQRDTGRVIHIDFGDTFET-----TI 2040
Query: 1318 KRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDH---ILDLFA 1374
R Y ++ PF LT +V ++GG F ELC N++R + +L++F
Sbjct: 2041 NRASYPEKVPFRLTRMIVNALDGGNVQGM----FTELCISTMNVLRQNKSSLVALLEIFI 2096
Query: 1375 LPSCDSGGSERT 1386
+ +ER+
Sbjct: 2097 HEPLEESSNERS 2108
>UniRef50_A7TLR7 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 2392
Score = 63.7 bits (148), Expect = 4e-08
Identities = 64/220 (29%), Positives = 100/220 (45%), Gaps = 41/220 (18%)
Query: 1149 FSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLK----AGLDLRM 1204
FSS P KIN +G+D + M K +D+RQD +Q MD + K +L +
Sbjct: 2080 FSSLKKPKKINIVGSDGNIYGIMCKK-EDVRQDNQYMQFATTMDFMLGKDVEATKRNLGI 2138
Query: 1205 VTFQALPTSNSKGMIEIVTEAETLRAIQTE-----------------WGL------TGSF 1241
T+ L G+IEI+ TLR++ E W G +
Sbjct: 2139 TTYSVLSLREDCGLIEIIPNVVTLRSVFVEKYESMKVKYSFKSLYEQWQQLPDEHKVGYY 2198
Query: 1242 KDK-----PIA-EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT 1295
KD+ P+ +W + P + + AR+ ++ S A ++ Y+LG+ DRH +NI+L
Sbjct: 2199 KDQISKFPPVLYQWFLETFPDPISWFNARNAYSRSNAVMAMVGYILGLGDRHCENILLDV 2258
Query: 1296 -SGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDM 1334
+G + H+DF D +F KRL + PF LT +M
Sbjct: 2259 ETGKVLHVDF-----DC-LFEKGKRLPIPEVVPFRLTQNM 2292
>UniRef50_A0E0Q4 Cluster: Chromosome undetermined scaffold_72, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_72, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 871
Score = 62.9 bits (146), Expect = 6e-08
Identities = 33/88 (37%), Positives = 51/88 (57%), Gaps = 3/88 (3%)
Query: 1147 TYFSSNTLPLKINFI---GTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR 1203
T FSS P+++ F G + + I +FK GDDLRQD LV+Q+ +MD L D++
Sbjct: 558 TIFSSAMAPIRLGFHVIKGDEESEIKLIFKNGDDLRQDQLVMQIFNLMDELLKGVSQDMK 617
Query: 1204 MVTFQALPTSNSKGMIEIVTEAETLRAI 1231
++ ++ L S S G +E V + TL+ I
Sbjct: 618 LLPYRILACSKSDGFLEFVPDNVTLQEI 645
Score = 59.7 bits (138), Expect = 6e-07
Identities = 41/117 (35%), Positives = 61/117 (52%), Gaps = 14/117 (11%)
Query: 1266 NFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYID 1324
N+ S AGY V TY LGI DRH +N+++ G +FHIDFG LG D + +
Sbjct: 711 NYIYSSAGYCVLTYFLGIGDRHLENLLINNEGKMFHIDFGFILGKDPKPY---------- 760
Query: 1325 RAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPSCDSG 1381
PF L +MV + GG++ + + F C + +R + I++LF L D+G
Sbjct: 761 PPPFKLCPEMVEAM-GGQK-SDLYTLFKSKCVEVYVYLRRYAKLIINLFLL-MADAG 814
Score = 36.7 bits (81), Expect = 4.9
Identities = 26/103 (25%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
Query: 897 MPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQ-LIGLLRLWEKPSPLNAMHL 955
+ ++ +++ + R + +Q ALP L + W EQ + L++ W + + L
Sbjct: 321 LKSDDKQLFVKYRYWAMQYGSALPFYLHSVA-WQNQKEEQDALTLMKKWSPIDREDCLFL 379
Query: 956 LLPCF-PDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 997
L F ++ A + L ++SD+ + VL QL QAL++E +
Sbjct: 380 LSSFFCASEFKKKYAVEQLGKLSDEKIENVLLQLVQALKYEPF 422
>UniRef50_Q98RM0 Cluster: Phosphatidylinositol 4-kinase; n=1;
Guillardia theta|Rep: Phosphatidylinositol 4-kinase -
Guillardia theta (Cryptomonas phi)
Length = 521
Score = 61.7 bits (143), Expect = 1e-07
Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 12/143 (8%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+ K D+ + + + + + + LD+ + + + + G+IEIV+ ++T+
Sbjct: 272 IIKNASDMHFEIIATIIFTESEKITREMFLDIWLNPYLCFKVNKTIGIIEIVSNSKTIHE 331
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQ-RARDNFTASCAGYSVATYLLGICDRHND 1289
I+ + SF + I EL Y R+NF S +GYS+ YLL I DRHN
Sbjct: 332 IKNDQNCINSFYNNFI----------ELYYSLEKRNNFYESMSGYSLLCYLLQIKDRHNC 381
Query: 1290 NIMLKTSGHLFHIDFGKFLGDAQ 1312
NI+L + L H+D+G F+ D Q
Sbjct: 382 NILLGSDNRLIHLDYG-FILDEQ 403
>UniRef50_A5DR49 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 2724
Score = 61.3 bits (142), Expect = 2e-07
Identities = 78/273 (28%), Positives = 124/273 (45%), Gaps = 51/273 (18%)
Query: 1137 YVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVG-DDLRQDALVLQVIKIMDTLW 1195
++ +D S +LP F+ +D A+FK G DDLRQD+++ QV + ++T+
Sbjct: 2374 FMKSIDGNISVAASGLSLPKIGKFLLSDGTYHRALFKSGTDDLRQDSIMEQVFEKVNTIL 2433
Query: 1196 LKAGL----DLRMVTFQALPTS----------NSKGMIEIVTE-------------AETL 1228
K LR+ T++A+P NS +I+I+ E +
Sbjct: 2434 EKDSATRKRSLRVRTYKAIPLGPKAGVIEYVPNSVALIDIIKPYHLKHDSIKAEKAREQM 2493
Query: 1229 RAIQTEWG-----LTGSFKDK--PIAEWLAKHNPSELE-YQRARDNFTASCAGYSVATYL 1280
++ Q + S K+K P+ + SE+E + +R +T A S+ Y+
Sbjct: 2494 KSCQNSSNSERIEVFKSIKNKVQPVLKEFFADTFSEVENWFESRVLYTRGIATTSIVGYV 2553
Query: 1281 LGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV--YV 1337
LG+ DRH +NI+L K SG HID G F K+L + PF LT D+V +
Sbjct: 2554 LGLGDRHCNNILLDKESGEPIHIDLG------VAFDQGKKLPIPETVPFRLTRDIVDGFG 2607
Query: 1338 INGGERPTQRFQHFVELCCMAFNIVRAHHDHIL 1370
I+G E F + C F +++ H DHIL
Sbjct: 2608 ISGVE------GIFRKSCEHTFRVMQLHSDHIL 2634
>UniRef50_Q4DM49 Cluster: Phosphatidylinositol kinase, putative; n=2;
Trypanosoma cruzi|Rep: Phosphatidylinositol kinase,
putative - Trypanosoma cruzi
Length = 1094
Score = 59.7 bits (138), Expect = 6e-07
Identities = 47/200 (23%), Positives = 86/200 (43%), Gaps = 19/200 (9%)
Query: 1127 PTALPLALHKYVHDLDVKSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQ 1186
P P ++++D S P+ I I ++K + L +D ++
Sbjct: 715 PILFPFDTSVVLNEIDFGGIVAMHSKQRPVLIPLIDEGGQTRCILYK-NESLEKDKVMCI 773
Query: 1187 VIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAI---QTEWGLTGSFK- 1242
+ + + K + + T+ +P S+S G+IEIV + T++++ E L +
Sbjct: 774 ASRFLQWVLYKQLRHVVLPTYHVMPLSSSSGIIEIVKDGHTVQSVIEPYKEHRLLQYLQQ 833
Query: 1243 -DKPIAEWLAKHNPSELEYQRA-------------RDNFTASCAGYSVATYLLGICDRHN 1288
++ A+ + P + + A R+NF S + + Y+ I DRH
Sbjct: 834 LEQQYAQQKEERQPKKQQEATASLKEAAKSSSVNVRENFLCSAKFFILMNYIFAIGDRHR 893
Query: 1289 DNIMLKTSGHLFHIDFGKFL 1308
DN+M+ SG +FHIDFG L
Sbjct: 894 DNVMVHPSGAIFHIDFGMLL 913
>UniRef50_Q4RZF8 Cluster: Chromosome 3 SCAF14932, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 3
SCAF14932, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2188
Score = 59.3 bits (137), Expect = 8e-07
Identities = 48/193 (24%), Positives = 86/193 (44%), Gaps = 30/193 (15%)
Query: 1147 TYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLD----L 1202
T + T P K+ F+G+D P +FK +DL D ++Q + I++T++ K
Sbjct: 1147 TILPTKTKPKKLFFMGSDGRNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKINQQEQPHF 1206
Query: 1203 RMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQR 1262
+ P G+I+ V A L + W + + L+ Q+
Sbjct: 1207 HACHYSVTPLGTRSGLIQWVDGATPLFGLYKRW----------------QQREAVLQAQK 1250
Query: 1263 ARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNFKRLV 1321
+ + S A S+ Y++G+ DRH DN+++ T+G + HID+ F K L
Sbjct: 1251 S---YARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYN------VCFEKGKSLR 1301
Query: 1322 YIDRAPFVLTHDM 1334
++ PF +TH++
Sbjct: 1302 VPEKVPFRMTHNI 1314
>UniRef50_UPI0000661579 Cluster: Homolog of Danio rerio
"Phosphoinositide-3-kinase, catalytic, gamma polypeptide;
n=1; Takifugu rubripes|Rep: Homolog of Danio rerio
"Phosphoinositide-3-kinase, catalytic, gamma polypeptide
- Takifugu rubripes
Length = 298
Score = 58.8 bits (136), Expect = 1e-06
Identities = 29/69 (42%), Positives = 45/69 (65%), Gaps = 1/69 (1%)
Query: 1183 LVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAI-QTEWGLTGSF 1241
L LQ++ IM+++W LDL ++ + + T N GMIEIV +A T+ I Q+ G TG+F
Sbjct: 92 LSLQILLIMESIWETESLDLCLLPYGCISTGNRIGMIEIVKDATTIANIQQSVVGSTGAF 151
Query: 1242 KDKPIAEWL 1250
KD+ + +WL
Sbjct: 152 KDEILCQWL 160
>UniRef50_Q0UIR4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 2310
Score = 58.8 bits (136), Expect = 1e-06
Identities = 49/172 (28%), Positives = 80/172 (46%), Gaps = 15/172 (8%)
Query: 1242 KDKPIA-EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGHL 1299
K +P+ EW + P + AR +T SCA S+ ++LG+ DRH +N++L+ +G
Sbjct: 2108 KFQPVLHEWFVETFPEPEAWFAARLRYTRSCAVMSIVGHVLGLGDRHGENVLLEQGNGGT 2167
Query: 1300 FHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAF 1359
FH+DF L D + LV PF LTH+MV + G + F+ EL +
Sbjct: 2168 FHVDF-NCLFDKGLTFEKPELV-----PFRLTHNMVDAM-GPQGVEGPFRKAAEL---TY 2217
Query: 1360 NIVRAHHDHILDLFALPSCDSGGSERTVAGGRPQMSLSGVPGVTSAAVSYVR 1411
+++R H D ++ + D G R + ++GV + VR
Sbjct: 2218 SLLRQHEDTLITILETFVHDPTAD---FLGNRKRKKIAGVADTPQEVLDIVR 2266
>UniRef50_A0CIQ9 Cluster: Chromosome undetermined scaffold_19, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_19, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 409
Score = 58.4 bits (135), Expect = 1e-06
Identities = 47/168 (27%), Positives = 75/168 (44%), Gaps = 10/168 (5%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+ K GD+L Q+ Q+I D +L+ + L+ F GMIE++ A T+ +
Sbjct: 156 IIKTGDNLTQEQFTSQLICQFDQ-FLRRKVCLQNQDFMKFNQGADFGMIEMIKNATTIDS 214
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDN 1290
+Q L F H + + Q+A + S YS+ Y L + DR++ N
Sbjct: 215 LQKN--LQKKFAQFIDFSDFLDHFRNNI--QQALQIYVQSLTAYSLVCYFLQVKDRNDGN 270
Query: 1291 IMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI 1338
I+L GHL HIDFG L K + + + PF + D + V+
Sbjct: 271 ILLDDEGHLIHIDFGFVLSIPG-----KVMKFEGKVPFKILSDYITVL 313
>UniRef50_Q6PJ60 Cluster: PIK3CB protein; n=8; Euteleostomi|Rep:
PIK3CB protein - Homo sapiens (Human)
Length = 139
Score = 58.0 bits (134), Expect = 2e-06
Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 5/78 (6%)
Query: 1299 LFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGER-PTQRFQHFVELCCM 1357
LFHIDFG LG+ + KR +R PF+LT+D ++VI G+ T++F F + C
Sbjct: 2 LFHIDFGHILGNFKSKFGIKR----ERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCED 57
Query: 1358 AFNIVRAHHDHILDLFAL 1375
A+ I+R H + + LFAL
Sbjct: 58 AYLILRRHGNLFITLFAL 75
>UniRef50_Q7R0U5 Cluster: GLP_186_22597_27513; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_186_22597_27513 - Giardia lamblia
ATCC 50803
Length = 1638
Score = 57.6 bits (133), Expect = 2e-06
Identities = 32/94 (34%), Positives = 48/94 (51%)
Query: 1216 KGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYS 1275
K ++E +T Q + + GS DK + +++ + NF S A YS
Sbjct: 1425 KWLVEQLTVKGIESLPQKVYAIIGSVIDKVYRFNGPLNCMNDITAEAQMSNFVKSTAAYS 1484
Query: 1276 VATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLG 1309
VATYLL DRH +N++++ G +FHIDFG G
Sbjct: 1485 VATYLLRAGDRHGENLLIRPDGRMFHIDFGWCFG 1518
Score = 44.0 bits (99), Expect = 0.032
Identities = 30/128 (23%), Positives = 60/128 (46%), Gaps = 5/128 (3%)
Query: 1136 KYVH--DLDVKSCTYFSSNTLPLKINFIGTDNAV-IPAMFKVGDDLRQDALVLQVIKIMD 1192
K+VH ++ + +S P+ + I + IP + K+ DD+R D L + + +MD
Sbjct: 1099 KFVHICGINPDNVKVMTSAKRPILYHLIQAETGKEIPVLLKINDDVRLDMLYVHLFSLMD 1158
Query: 1193 TLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAI--QTEWGLTGSFKDKPIAEWL 1250
+ LD++ + S S G IE + +E+ I + E G + + + ++
Sbjct: 1159 SYMQTHNLDMKFTIYSCFALSPSIGFIECILPSESQDDIYKKKELGTITDYFNAMLCKYR 1218
Query: 1251 AKHNPSEL 1258
++ +PS L
Sbjct: 1219 SQVSPSVL 1226
>UniRef50_Q1JTH0 Cluster: Phosphatidylinositol 4-kinase, putative;
n=1; Toxoplasma gondii RH|Rep: Phosphatidylinositol
4-kinase, putative - Toxoplasma gondii RH
Length = 1230
Score = 57.2 bits (132), Expect = 3e-06
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 16/148 (10%)
Query: 1266 NFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFK----RLV 1321
NF S A YS+ +Y L + DRHN N++L GHL HID+G L ++ NF+ +L
Sbjct: 1051 NFIESHAAYSLVSYFLQVKDRHNGNLLLDAEGHLIHIDYGYLLSNSPGNINFETSPFKLT 1110
Query: 1322 YID---RAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFAL--- 1375
RA + + V++G + +++F L F R H D I+ L +
Sbjct: 1111 QASQKKRAAEKSITEFLDVMDG--ETSDNYEYFRTLIIRGFLEARKHADRIILLVEMMLS 1168
Query: 1376 ---PSCDSGGSERTVAGGRPQMSLSGVP 1400
C SGG + T+ R + + G+P
Sbjct: 1169 ATKMPCFSGGPQYTLDALRERFMI-GLP 1195
>UniRef50_Q1DMF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 2287
Score = 57.2 bits (132), Expect = 3e-06
Identities = 70/259 (27%), Positives = 110/259 (42%), Gaps = 50/259 (19%)
Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLD-----LRMVTFQA 1209
P KI+ G+D V + K DDLR+D +++ M +LK L+ L + T+
Sbjct: 1948 PRKISIRGSDGKVYSLLCKPKDDLRKDQRLMEY-NTMINRFLKRDLESNKRRLYIKTYAV 2006
Query: 1210 LPTSNSKGMIE----------IVTEAETLRAIQTEWG-----LTG-SFKDKPIA------ 1247
P + G+IE IVT+ R I + LT S D +A
Sbjct: 2007 TPLNERCGLIEWVDGLRPLREIVTKLLKARGIMINYTEIKHYLTETSSSDSKLAAFSKLL 2066
Query: 1248 --------EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGH 1298
EW + P + AR +T SCA S+ LG+ DRH +NI+ + +G
Sbjct: 2067 TKYPPVLHEWFVEMFPEPSAWLTARLRYTRSCAVMSMVGSSLGLGDRHGENILFEEGTGE 2126
Query: 1299 LFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV-----YVINGGERPTQRFQHFVE 1353
+ H+DF +F L + PF LTH+M+ Y NG P +R F +
Sbjct: 2127 ILHVDFN------CLFDKGLTLEMPELVPFRLTHNMIDAFGAYGYNGCSSPNRR--PFRK 2178
Query: 1354 LCCMAFNIVRAHHDHILDL 1372
C + ++R + D ++ +
Sbjct: 2179 TCELTQGLLRQNEDSLMTI 2197
>UniRef50_Q5AXK5 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized protein
- Emericella nidulans (Aspergillus nidulans)
Length = 2364
Score = 56.8 bits (131), Expect = 4e-06
Identities = 72/281 (25%), Positives = 124/281 (44%), Gaps = 56/281 (19%)
Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLD-----LRMVTFQA 1209
P KI+ G+D + + K DDLR+D +++ +++ +LK ++ + + T+
Sbjct: 1902 PRKISIRGSDGRIYNILCKPKDDLRKDQRLMEFNNMINR-FLKKDVESSKRRMYIKTYAV 1960
Query: 1210 LPTSNSKGMIEIVTEAETLRAIQT----EWGLTGS--------------------FKDKP 1245
P + G+IE V TLR + T E G+T + F DK
Sbjct: 1961 TPLNEECGLIEWVDNLRTLRDLVTRALKERGITPNYDEIRHYLNEACSDPSKVSIFTDKV 2020
Query: 1246 IA-------EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SG 1297
+A EW + P + AR +T SCA S+ Y+LG+ DRH +NI+ + +G
Sbjct: 2021 LATFPPVLHEWFVEMFPETGAWFAARLRYTRSCAVMSMVGYVLGLGDRHGENILFEEGTG 2080
Query: 1298 HLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV--YVINGGERPTQRFQHFVELC 1355
+ H+DF L D + + LV PF LT +M+ + G P F + C
Sbjct: 2081 GILHVDF-NCLFDKGLTFDKPELV-----PFRLTQNMIDAFGAYGYNGP------FRKTC 2128
Query: 1356 CMAFNIVRAHHDHILDLFAL----PSCDSGGSERTVAGGRP 1392
++ +++R + D ++ + P+ D G +R P
Sbjct: 2129 ELSLDLLRQNEDALMTILETFLHDPTTDFIGKKRRTHANVP 2169
>UniRef50_UPI0000E49F1A Cluster: PREDICTED: similar to Pik3c3-prov
protein, partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Pik3c3-prov protein, partial -
Strongylocentrotus purpuratus
Length = 231
Score = 56.4 bits (130), Expect = 6e-06
Identities = 30/65 (46%), Positives = 41/65 (63%), Gaps = 2/65 (3%)
Query: 1130 LPLALHKYVHDLDV--KSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQV 1187
LPL LH V L V + + F S+ +P+K+ F TD+ A+ K GDDLRQD L+LQ+
Sbjct: 166 LPLPLHPEVKVLGVVAEKASMFKSSLMPIKLTFKTTDHEEYVAICKNGDDLRQDQLILQI 225
Query: 1188 IKIMD 1192
I +MD
Sbjct: 226 ITLMD 230
>UniRef50_A5K647 Cluster: Phosphatidylinositol 3-and 4-kinase,
putative; n=4; cellular organisms|Rep:
Phosphatidylinositol 3-and 4-kinase, putative -
Plasmodium vivax
Length = 4367
Score = 56.4 bits (130), Expect = 6e-06
Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 6/112 (5%)
Query: 1260 YQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKR 1319
Y A NF S A YS+ +++L + DRHN N++ G++ HIDFG L ++
Sbjct: 4195 YIYALKNFICSLAAYSLLSFVLQVKDRHNGNLLFDDYGNIIHIDFGYIL---NIYPGIS- 4250
Query: 1320 LVYIDRAPFVLTHDMVYVINGGERPTQRFQH-FVELCCMAFNIVRAHHDHIL 1370
+ + APF LT +M+ ++ + Q F +++L + ++R D ++
Sbjct: 4251 -INFELAPFKLTREMIMLLTIKSQKKQYFIFTYIQLVVKGYLLLREKSDWLI 4301
>UniRef50_Q24FA9 Cluster: Phosphatidylinositol 3-and 4-kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3-and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 2086
Score = 56.0 bits (129), Expect = 7e-06
Identities = 37/129 (28%), Positives = 69/129 (53%), Gaps = 11/129 (8%)
Query: 1259 EYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNF 1317
++ A++N+ + A + + YL+G+ DRH DNI++ K +G + HID+ A +FG+
Sbjct: 1919 QWYTAKENYLRTYASWCILGYLIGLGDRHTDNILIKKINGEIVHIDY------ALIFGSG 1972
Query: 1318 KRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHILDLFALPS 1377
K+L + PF LT +M + + G + F+ + CM F+ H D I+ + +
Sbjct: 1973 KQLNVPETIPFRLTKNMEFAL-GSFKSYGLFRKAMIDICMCFS---KHLDDIIGFWDCFT 2028
Query: 1378 CDSGGSERT 1386
+ G ++T
Sbjct: 2029 NELEGCKKT 2037
>UniRef50_Q8SSE7 Cluster: PROTEIN KINASE OF THE PI3/PI4 FAMILY; n=1;
Encephalitozoon cuniculi|Rep: PROTEIN KINASE OF THE
PI3/PI4 FAMILY - Encephalitozoon cuniculi
Length = 1935
Score = 56.0 bits (129), Expect = 7e-06
Identities = 52/214 (24%), Positives = 91/214 (42%), Gaps = 33/214 (15%)
Query: 1149 FSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQ 1208
F+S P +I F+G+D + K DDLR+D+ + + I++++ K + T+
Sbjct: 1631 FNSLQRPKRICFVGSDGKNYYWLCKNQDDLRKDSRFMDLNLIINSILKKQSSRKYIRTYA 1690
Query: 1209 ALPTSNSKGMIEIVTEAETLRAI--------------------------QTEWGLTGSFK 1242
+P S+ G+IE + +L+AI EW S
Sbjct: 1691 VIPFSHESGIIEWIGGLSSLKAICDTYYARDGISISETACRFVHNKKIGMREWHRVASKF 1750
Query: 1243 DKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFH 1301
W P + AR+N+T + A ++ + +G+ DRH +NI+ +G H
Sbjct: 1751 HPKFHLWFHDSFPHPFSWLVARNNYTQTYAIMNIVGWFMGLGDRHAENILFDSNTGDTVH 1810
Query: 1302 IDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+D +FG K L +R P+ LT ++V
Sbjct: 1811 VDLN------CIFGKGKELQVPERVPYRLTQNIV 1838
>UniRef50_Q1XH09 Cluster: Phosphatidyl inositol 3-kinase; n=1;
Neurospora crassa|Rep: Phosphatidyl inositol 3-kinase -
Neurospora crassa
Length = 2484
Score = 55.6 bits (128), Expect = 1e-05
Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 1239 GSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SG 1297
G F D + EW P + AR +T SCA S+ +LG+ DRH +N++L+ +G
Sbjct: 2282 GMFPDV-LPEWFISQFPDPSAWFAARLRYTRSCAVMSMVGTILGLGDRHGENVLLEEGNG 2340
Query: 1298 HLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+FH+DF F ++ PF LTH+M+
Sbjct: 2341 GVFHVDFNCLFDKGLTFAQ------PEKVPFRLTHNMI 2372
>UniRef50_A6SF30 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 2088
Score = 55.2 bits (127), Expect = 1e-05
Identities = 33/94 (35%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 1244 KPIA-EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGHLFH 1301
KP+ +W K P + AR +T SCA S+ +LG+ DRH +NI+ + +G FH
Sbjct: 1885 KPVFHKWFVKQFPEPSAWFAARLRYTRSCAVMSMVGTILGLGDRHTENILFEEGNGGTFH 1944
Query: 1302 IDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+DF +F K ++ PF LTH+MV
Sbjct: 1945 VDFN------CLFEKGKTFAKPEQVPFRLTHNMV 1972
>UniRef50_A7QH41 Cluster: Chromosome chr3 scaffold_95, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_95, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 2394
Score = 54.8 bits (126), Expect = 2e-05
Identities = 44/125 (35%), Positives = 63/125 (50%), Gaps = 16/125 (12%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL K SE+ R R N+T S A S+ YLLG+ DRH N+ML + SG + HIDFG
Sbjct: 2152 WL-KSRTSEVWLDR-RTNYTRSLAVMSMVGYLLGLGDRHPSNLMLHRYSGKILHIDFGDC 2209
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMVYV--INGGERPTQRFQHFVELCCMAFNIVRAH 1365
+A M R + ++ PF LT +V ++G E +F C ++R H
Sbjct: 2210 F-EASM----NREKFPEKVPFRLTRMLVKAMEVSGIE------GNFRSTCENVMQVLRTH 2258
Query: 1366 HDHIL 1370
D ++
Sbjct: 2259 RDSVM 2263
Score = 39.5 bits (88), Expect = 0.69
Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLW----LKAGLDLRMV 1205
+S P K+ G+D + K +DLRQD V+Q+ +++TL A DL +
Sbjct: 2012 TSKQRPRKLTIRGSDGEDYAFLLKGHEDLRQDERVMQLFGLVNTLLENERKTAEKDLSIQ 2071
Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAIQTEW 1235
+ +P S + G+I V +TL + E+
Sbjct: 2072 RYAVIPLSPNSGLIGWVPHCDTLHHLIREY 2101
>UniRef50_A2DPS8 Cluster: PIKK family atypical protein kinase; n=1;
Trichomonas vaginalis G3|Rep: PIKK family atypical
protein kinase - Trichomonas vaginalis G3
Length = 2268
Score = 54.8 bits (126), Expect = 2e-05
Identities = 34/94 (36%), Positives = 47/94 (50%), Gaps = 6/94 (6%)
Query: 1243 DKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFH 1301
D IA +L + + R R F SCA S Y++G+ DRH NIM+ + +G + H
Sbjct: 2051 DTDIANFLWLQSKDAEHWMRIRTTFAVSCAVNSAIGYVIGLGDRHPSNIMIDRNTGKMIH 2110
Query: 1302 IDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
IDFG A KR +Y + PF LT +V
Sbjct: 2111 IDFGDCFEVA-----MKRKLYPEVVPFRLTRMLV 2139
Score = 39.9 bits (89), Expect = 0.52
Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 1149 FSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMV--T 1206
++S P I+ +G D V + K +DLR D ++Q +++L +K V T
Sbjct: 1913 YTSKQQPKSISVMGDDGKVYQYLLKGHEDLRLDERIMQFFSTVNSL-IKTSFAKSTVIKT 1971
Query: 1207 FQALPTSNSKGMIEIVTEAETLRAIQTEW 1235
+P S G+++ V A+TL++I ++
Sbjct: 1972 MVVMPLSKLNGLVQWVNGADTLKSIVEQY 2000
>UniRef50_UPI00006CBC83 Cluster: Phosphatidylinositol 3- and 4-kinase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3- and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 2540
Score = 54.4 bits (125), Expect = 2e-05
Identities = 36/88 (40%), Positives = 50/88 (56%), Gaps = 8/88 (9%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL N SE+ +R R N+T S A S+A Y+LG+ DRH NIML + +G + HIDFG
Sbjct: 2250 WLKSPN-SEIWLER-RTNYTRSLATMSIAGYILGLGDRHPSNIMLQRYTGKIVHIDFGDC 2307
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
A +R + ++ PF LT +V
Sbjct: 2308 FEVA-----MRREKFPEKVPFRLTRMLV 2330
>UniRef50_Q38GA3 Cluster: Target of rapamycin kinase; n=2;
Chlorophyta|Rep: Target of rapamycin kinase -
Chlamydomonas reinhardtii
Length = 2523
Score = 54.4 bits (125), Expect = 2e-05
Identities = 37/88 (42%), Positives = 49/88 (55%), Gaps = 8/88 (9%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL N SE+ R R N+T S A S+ Y+LG+ DRH N+ML + SG L HIDFG
Sbjct: 2245 WLKSRN-SEVWLDR-RTNYTRSAAVMSMVGYILGLGDRHPSNLMLDRYSGKLLHIDFGDC 2302
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+A M R + ++ PF LT M+
Sbjct: 2303 F-EASM----NREKFPEKVPFRLTRMMI 2325
Score = 45.6 bits (103), Expect = 0.011
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLW----LKAGLDLRMV 1205
SS P K+ G D A + K +DLRQD V+Q+ +++T+ + A DL +
Sbjct: 2105 SSKQRPRKLTIHGGDGAEYMFLLKGHEDLRQDERVMQLFGLVNTMLAHDRITAERDLSIA 2164
Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAIQTEW 1235
+ +P S + G+I V +TL A+ E+
Sbjct: 2165 RYAVIPLSPNSGLIGWVPNCDTLHALIREY 2194
>UniRef50_Q4DEX9 Cluster: Phosphatidylinositol 3-related kinase,
putative; n=3; Trypanosoma cruzi|Rep:
Phosphatidylinositol 3-related kinase, putative -
Trypanosoma cruzi
Length = 2897
Score = 54.4 bits (125), Expect = 2e-05
Identities = 32/96 (33%), Positives = 54/96 (56%), Gaps = 8/96 (8%)
Query: 1242 KDKPIAE-WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLK-TSGHL 1299
K +P+ W +H S E+ AR+++T + A +S+A +++G+ DRH +N+ML G L
Sbjct: 2691 KTRPVLHGWFHRHFHSHQEWFNARNSYTQATALWSIAGHIVGLGDRHGENLMLDLRCGEL 2750
Query: 1300 FHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
H+DF A +F + L +R F LT ++V
Sbjct: 2751 MHVDF------ACLFDKGESLEVPERVRFRLTQNVV 2780
>UniRef50_A7F1X6 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 2165
Score = 54.4 bits (125), Expect = 2e-05
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
Query: 1248 EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGHLFHIDFGK 1306
+W K P + AR +T SCA S+ +LG+ DRH +NI+ + +G FH+DF
Sbjct: 1989 KWFVKQFPEPSAWFAARLRYTRSCAVMSMVGTILGLGDRHTENILFEEGNGGTFHVDFN- 2047
Query: 1307 FLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+F K ++ PF LTH+MV
Sbjct: 2048 -----CLFEKGKTFTKPEQVPFRLTHNMV 2071
>UniRef50_A4RPR6 Cluster: Putative uncharacterized protein; n=4;
Pezizomycotina|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 2231
Score = 54.4 bits (125), Expect = 2e-05
Identities = 36/91 (39%), Positives = 48/91 (52%), Gaps = 8/91 (8%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL K SE +R R N+T S S+ Y+LG+ DRH N+ML + +G + HIDFG
Sbjct: 2147 WL-KSKSSEAWLER-RTNYTRSLGVMSMVGYILGLGDRHPSNLMLDRVTGKIIHIDFGDC 2204
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI 1338
A KR Y +R PF LT + Y +
Sbjct: 2205 FEVAT-----KREKYPERVPFRLTRMLTYAM 2230
Score = 48.0 bits (109), Expect = 0.002
Identities = 27/90 (30%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAG----LDLRMV 1205
SS P K+N +G+D A + K +D+RQD V+Q+ + +TL L +
Sbjct: 2007 SSKQRPRKLNMMGSDGASYTFLLKGHEDIRQDERVMQLFGLCNTLLASDSESYKRHLSIQ 2066
Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAIQTEW 1235
++ A+P S+S G++ V ++T+ A+ E+
Sbjct: 2067 SYPAIPLSHSSGLLGWVPNSDTIHALIREY 2096
>UniRef50_A2ELE0 Cluster: PIKK family atypical protein kinase; n=1;
Trichomonas vaginalis G3|Rep: PIKK family atypical
protein kinase - Trichomonas vaginalis G3
Length = 2163
Score = 54.0 bits (124), Expect = 3e-05
Identities = 34/97 (35%), Positives = 52/97 (53%), Gaps = 6/97 (6%)
Query: 1246 IAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDF 1304
I E L +P + + + FT S A S+A Y++G+ DRH NIM+ + +G + HIDF
Sbjct: 1972 IREMLWLRSPGASSWIQRSNCFTVSTALMSMAGYVIGLGDRHPSNIMVQRHTGRVIHIDF 2031
Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGG 1341
G DA R ++ +R F LT +V ++GG
Sbjct: 2032 GFSFEDA-----MNRTLFPERVQFRLTRMIVNALDGG 2063
>UniRef50_Q54TG2 Cluster: Protein kinase, Atypical group; n=2;
Dictyostelium discoideum|Rep: Protein kinase, Atypical
group - Dictyostelium discoideum AX4
Length = 2380
Score = 53.6 bits (123), Expect = 4e-05
Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 8/88 (9%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL N SE+ R R N+T S A S+ Y+LG+ DRH N+ML + +GH+ HIDFG
Sbjct: 2112 WLKSRN-SEVWLDR-RTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRHTGHILHIDFGDC 2169
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
A R Y ++ PF LT ++
Sbjct: 2170 FEVA-----MHRDKYPEKIPFRLTRMLI 2192
Score = 39.5 bits (88), Expect = 0.69
Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 1151 SNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWL----KAGLDLRMVT 1206
S P K+ IG+D + K +DLRQD V+Q+ +++ L A L +
Sbjct: 1973 SKQRPRKLTIIGSDGLEYTFLLKGHEDLRQDERVMQLFSLVNNLLSANHETAKSHLSIRR 2032
Query: 1207 FQALPTSNSKGMIEIVTEAETLRAI 1231
F +P S + G+I V ++TL +
Sbjct: 2033 FSVIPLSPNSGLIGWVPHSDTLHTL 2057
>UniRef50_Q2I6W1 Cluster: Target of rapamycin; n=4;
Sordariomycetes|Rep: Target of rapamycin - Podospora
anserina
Length = 2433
Score = 53.6 bits (123), Expect = 4e-05
Identities = 36/91 (39%), Positives = 47/91 (51%), Gaps = 8/91 (8%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL K SE R R N+T S S+ Y+LG+ DRH N+ML + +G + HIDFG
Sbjct: 2164 WL-KSKSSEAWLDR-RTNYTRSLGVMSMVGYILGLGDRHPSNLMLDRITGKIIHIDFGDC 2221
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI 1338
A KR Y +R PF LT + Y +
Sbjct: 2222 FEVA-----MKREKYPERVPFRLTRMLTYAM 2247
Score = 42.7 bits (96), Expect = 0.074
Identities = 23/89 (25%), Positives = 45/89 (50%), Gaps = 4/89 (4%)
Query: 1147 TYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAG----LDL 1202
T SS P K++ +G+D + K +D+RQD V+Q+ + +TL L
Sbjct: 2021 TVISSKQRPRKLDIVGSDGKTYTFLLKGHEDIRQDERVMQLFGLCNTLLANDSECYKRHL 2080
Query: 1203 RMVTFQALPTSNSKGMIEIVTEAETLRAI 1231
+ + A+P S + G++ V +++T+ +
Sbjct: 2081 NIQRYPAIPLSQNSGLLGWVPDSDTIHQL 2109
>UniRef50_Q2GTI4 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized protein
- Chaetomium globosum (Soil fungus)
Length = 2208
Score = 53.6 bits (123), Expect = 4e-05
Identities = 36/91 (39%), Positives = 47/91 (51%), Gaps = 8/91 (8%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL K SE R R N+T S S+ Y+LG+ DRH N+ML + +G + HIDFG
Sbjct: 1935 WL-KSKSSEAWLDR-RTNYTRSLGVMSMVGYILGLGDRHPSNLMLDRITGKIIHIDFGDC 1992
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI 1338
A KR Y +R PF LT + Y +
Sbjct: 1993 FEVA-----MKREKYPERVPFRLTRMLTYAM 2018
Score = 39.1 bits (87), Expect = 0.91
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAG----LDLRMV 1205
SS P K+ IG D + K +D+RQD V+Q+ + +TL L +
Sbjct: 1795 SSKQRPRKLAIIGGDGKTYSFLLKGHEDIRQDERVMQLFGLCNTLLANDSESYKRHLNIQ 1854
Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAIQTEW 1235
+ A+P S + G++ V ++T+ + E+
Sbjct: 1855 RYPAIPLSQNSGLLGWVPNSDTVHQLIREY 1884
>UniRef50_Q9VK45 Cluster: CG5092-PA; n=9; Eumetazoa|Rep: CG5092-PA -
Drosophila melanogaster (Fruit fly)
Length = 2470
Score = 53.2 bits (122), Expect = 5e-05
Identities = 29/58 (50%), Positives = 39/58 (67%), Gaps = 3/58 (5%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFG 1305
WL K SEL ++R R+N+T S A S+ Y+LG+ DRH N+ML + SG + HIDFG
Sbjct: 2225 WL-KSPSSELWFER-RNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFG 2280
>UniRef50_UPI00006CBC84 Cluster: Phosphatidylinositol 3- and 4-kinase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
Phosphatidylinositol 3- and 4-kinase family protein -
Tetrahymena thermophila SB210
Length = 2452
Score = 52.8 bits (121), Expect = 7e-05
Identities = 36/88 (40%), Positives = 49/88 (55%), Gaps = 8/88 (9%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL N SE+ +R R N+T S A S+A Y+LG+ DRH NIML + +G + HIDFG
Sbjct: 2192 WLKSPN-SEIWLER-RTNYTRSLATMSIAGYILGLGDRHLSNIMLQRQTGKIVHIDFGDC 2249
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
A +R ++ PF LT +V
Sbjct: 2250 FEVA-----MRRESLPEKVPFRLTRMLV 2272
>UniRef50_Q2KGF1 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea 70-15
Length = 2335
Score = 52.8 bits (121), Expect = 7e-05
Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 7/90 (7%)
Query: 1246 IAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGHLFHIDF 1304
+ W P + AR +T SCA S+ +LG+ DRH +N++L+ +G +FH+DF
Sbjct: 2135 LPSWFVSQFPEPSAWFAARLKYTRSCAVMSMVGTILGLGDRHGENVLLEEGNGGVFHVDF 2194
Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDM 1334
F +R PF LTH+M
Sbjct: 2195 NCLFDKGLTFAT------PERVPFRLTHNM 2218
>UniRef50_A5E2Q8 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 2471
Score = 52.8 bits (121), Expect = 7e-05
Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query: 1242 KDKPIAE-WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHL 1299
K++P+ W + + AR+ FT S A S+ YL+G+ DRH +NI+L K SG +
Sbjct: 2278 KNEPLLHHWFVEEFSDPSSWYIARNEFTRSSAVMSIVGYLIGLGDRHCENILLFKKSGAV 2337
Query: 1300 FHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
HIDF D +F K L + PF LT +MV
Sbjct: 2338 LHIDF-----DC-LFEKGKSLPTPEVVPFRLTQNMV 2367
>UniRef50_A4RC96 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 2283
Score = 52.8 bits (121), Expect = 7e-05
Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 7/90 (7%)
Query: 1246 IAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGHLFHIDF 1304
+ W P + AR +T SCA S+ +LG+ DRH +N++L+ +G +FH+DF
Sbjct: 2083 LPSWFVSQFPEPSAWFAARLKYTRSCAVMSMVGTILGLGDRHGENVLLEEGNGGVFHVDF 2142
Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDM 1334
F +R PF LTH+M
Sbjct: 2143 NCLFDKGLTFAT------PERVPFRLTHNM 2166
>UniRef50_Q9LPM4 Cluster: F2J10.9 protein; n=3; Arabidopsis
thaliana|Rep: F2J10.9 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 2513
Score = 52.4 bits (120), Expect = 9e-05
Identities = 36/88 (40%), Positives = 50/88 (56%), Gaps = 8/88 (9%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL K SE+ +R R N+T S A S+ Y+LG+ DRH N+ML + SG + HIDFG
Sbjct: 2236 WL-KSRSSEVWLER-RTNYTRSLAVMSMVGYILGLGDRHPSNLMLHRYSGKILHIDFGDC 2293
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+A M R + ++ PF LT +V
Sbjct: 2294 F-EASM----NREKFPEKVPFRLTRMLV 2316
Score = 38.7 bits (86), Expect = 1.2
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLW----LKAGLDLRMV 1205
+S P K+ G D + K +DLRQD V+Q+ +++TL A DL +
Sbjct: 2096 TSKQRPRKLTIHGNDGEDYAFLLKGHEDLRQDERVMQLFGLVNTLLENSRKTAEKDLSIQ 2155
Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAIQTE 1234
+ +P S + G+I V +TL + E
Sbjct: 2156 RYSVIPLSPNSGLIGWVPNCDTLHHLIRE 2184
>UniRef50_A2ELF3 Cluster: PIKK family atypical protein kinase; n=2;
Trichomonas vaginalis G3|Rep: PIKK family atypical
protein kinase - Trichomonas vaginalis G3
Length = 2251
Score = 52.4 bits (120), Expect = 9e-05
Identities = 40/124 (32%), Positives = 61/124 (49%), Gaps = 13/124 (10%)
Query: 1254 NPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQ 1312
+PS ++ NF+ SCA S+ Y++G+ DRH NIM+ + +G + HIDF GD
Sbjct: 2035 SPSAADWVLHLVNFSQSCAMMSMIGYIIGLGDRHPSNIMIHQRTGSMIHIDF----GDCF 2090
Query: 1313 MFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHI--- 1369
K + + + PF LT V PT+ +F C +++R H D I
Sbjct: 2091 EVNKIK-VRFPETIPFRLTRMFVNAFG----PTKIEGNFRITCKEVLSLMRTHKDSIMAV 2145
Query: 1370 LDLF 1373
LD+F
Sbjct: 2146 LDIF 2149
>UniRef50_A1C8Y6 Cluster: Phosphatidylinositol 3-and 4-kinase,
putative; n=7; Trichocomaceae|Rep: Phosphatidylinositol
3-and 4-kinase, putative - Aspergillus clavatus
Length = 2469
Score = 52.4 bits (120), Expect = 9e-05
Identities = 37/115 (32%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Query: 1248 EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGHLFHIDFGK 1306
EW + P + AR +T SCA S+ Y+LG+ DRH +NI+ + +G + H+DF
Sbjct: 2257 EWFVEMFPETGTWFTARLRYTRSCAVMSMVGYVLGLGDRHGENILFEEGTGGIIHVDF-N 2315
Query: 1307 FLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVING-GERPTQRFQHFVELCCMAFN 1360
L D + + LV PF LTH+M+ G R + LC + N
Sbjct: 2316 CLFDKGLTFDKPELV-----PFRLTHNMIDAFGAYGYNGPYRRTSEISLCLLRQN 2365
>UniRef50_P38110 Cluster: Serine/threonine-protein kinase TEL1; n=3;
cellular organisms|Rep: Serine/threonine-protein kinase
TEL1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 2787
Score = 52.4 bits (120), Expect = 9e-05
Identities = 60/220 (27%), Positives = 98/220 (44%), Gaps = 44/220 (20%)
Query: 1153 TLPLKINFIGTDNAVIPAMFK-VGDDLRQDALVLQVI----KIMDTLWLKAGLDLRMVTF 1207
+LP + F +D A+ K DDLRQDA++ QV K++ + LDL + T+
Sbjct: 2445 SLPKIVTFNISDGTTQKALMKGSNDDLRQDAIMEQVFQQVNKVLQNDKVLRNLDLGIRTY 2504
Query: 1208 QALP----------TSNSKGMIEIVTEAET------------LRAIQTEWG--------- 1236
+ +P +NS + +I+++ T ++A+QT+
Sbjct: 2505 KVVPLGPKAGIIEFVANSTSLHQILSKLHTNDKITFDQARKGMKAVQTKSNEERLKAYLK 2564
Query: 1237 LTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKTS 1296
+T K + + + P L++ A+ +T A S+ Y+LG+ DRH +NI+L S
Sbjct: 2565 ITNEIKPQ-LRNFFFDSFPDPLDWFEAKKTYTKGVAASSIVGYILGLGDRHLNNILLDCS 2623
Query: 1297 -GHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
G HID G F K L + PF LT D+V
Sbjct: 2624 TGEPIHIDLG------IAFDQGKLLPIPELVPFRLTRDIV 2657
>UniRef50_UPI0000DB7A76 Cluster: PREDICTED: similar to DNA-dependent
protein kinase catalytic subunit (DNA-PK catalytic
subunit) (DNA-PKcs) (P460); n=1; Apis mellifera|Rep:
PREDICTED: similar to DNA-dependent protein kinase
catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs)
(P460) - Apis mellifera
Length = 673
Score = 52.0 bits (119), Expect = 1e-04
Identities = 52/164 (31%), Positives = 76/164 (46%), Gaps = 13/164 (7%)
Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMD-TLWLKAGLDLRMV---TFQA- 1209
P++I IG D + K G+DLRQD + Q+ IM+ TL++ A R + T+QA
Sbjct: 389 PIRITMIGNDAKDYHFLVKFGEDLRQDQRLQQLFTIMNKTLYINAACRQRQLLIDTYQAK 448
Query: 1210 --LPTSNSKGMI-EIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKH----NPSELEYQR 1262
+ SK ++ E EA + F +K + L K PS +
Sbjct: 449 WIQKAAPSKKLVHEKYKEAVVKYNASEVYTKMNEFINKTKWDSLRKTLIVLCPSIESFII 508
Query: 1263 ARDNFTASCAGYSVATYLLGICDRHNDN-IMLKTSGHLFHIDFG 1305
R NF S A +A ++LGI DRH N +++ SG IDFG
Sbjct: 509 MRRNFITSYATMCIAHWILGIGDRHLQNTLIVIDSGRCLGIDFG 552
>UniRef50_UPI000049A59C Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 2410
Score = 52.0 bits (119), Expect = 1e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWL--KAGLDLRMVTFQALPT 1212
P K+ F+G+DN + K DDLRQDA++ Q+ + + L+ + LR+ T++ +P
Sbjct: 2065 PKKMEFLGSDNKKYSFLLKSEDDLRQDAVMQQLFDLCNRLFKQHQQTKQLRIRTYKVVPL 2124
Query: 1213 SNSKGMIEIVTEAETL 1228
+ GM+E VT E L
Sbjct: 2125 TKESGMLEFVTGTEPL 2140
Score = 41.5 bits (93), Expect = 0.17
Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 7/71 (9%)
Query: 1266 NFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNFKRLVYID 1324
N+ S A S+ Y+ GI DRHN+NIM + + + HIDFG FG K+L +
Sbjct: 2217 NYINSTAVSSIIGYVFGIGDRHNNNIMFDEATAEVIHIDFGIVF----EFG--KKLPIPE 2270
Query: 1325 RAPFVLTHDMV 1335
PF LT +++
Sbjct: 2271 IVPFRLTREIL 2281
>UniRef50_Q5C1Z3 Cluster: SJCHGC04717 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04717 protein - Schistosoma
japonicum (Blood fluke)
Length = 305
Score = 52.0 bits (119), Expect = 1e-04
Identities = 29/97 (29%), Positives = 57/97 (58%), Gaps = 5/97 (5%)
Query: 1171 MFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRA 1230
+FKVGDD+RQD L LQ++++ ++ + GL+L + ++ + T+ +G+IE V ++++
Sbjct: 211 IFKVGDDVRQDILALQILQLFKNIFERCGLELYVYPYRVVATAPGRGVIECVPDSKSRDQ 270
Query: 1231 IQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNF 1267
I + G + ++ + + P+ YQ AR NF
Sbjct: 271 IGRQ--TDGKLYEYFLSIYGDETTPT---YQSARRNF 302
>UniRef50_Q4Q288 Cluster: Phosphatidylinositol 3-kinase (Tor2)-like
protein; n=5; cellular organisms|Rep:
Phosphatidylinositol 3-kinase (Tor2)-like protein -
Leishmania major
Length = 2438
Score = 52.0 bits (119), Expect = 1e-04
Identities = 40/109 (36%), Positives = 58/109 (53%), Gaps = 10/109 (9%)
Query: 1200 LDLRMVTFQALPTSNSKGM--IEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSE 1257
L++RM+ Q + NSK + I+++ E L + S +D A W N E
Sbjct: 2144 LEMRMLD-QIITFDNSKAYDYLTIMSKVEVLEFLSDHT----SGQDIRKAMWSTSPN-CE 2197
Query: 1258 LEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFG 1305
+ Y R R +T S A S+ Y+LG+ DRH +NIML + SG + HIDFG
Sbjct: 2198 VWYDRRR-MYTTSLANMSIVGYILGLGDRHPNNIMLQRASGLVVHIDFG 2245
>UniRef50_Q2H501 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized protein
- Chaetomium globosum (Soil fungus)
Length = 2601
Score = 52.0 bits (119), Expect = 1e-04
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 1246 IAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT-SGHLFHIDF 1304
+ EW P+ + AR +T SCA S+ +LG+ DRH +N++L+ +G +FH+DF
Sbjct: 2034 LPEWFIAQFPNPSAWFAARLKYTRSCAVMSMVGTILGLGDRHGENVLLEEGNGGIFHVDF 2093
Query: 1305 GKFLGDAQMFGNFKRLVYIDRAPFVLTHDM 1334
MF + PF LTH+M
Sbjct: 2094 N------CMFDKGMTFPQPECVPFRLTHNM 2117
>UniRef50_A7F5R9 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Sclerotinia sclerotiorum 1980
Length = 2430
Score = 52.0 bits (119), Expect = 1e-04
Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 8/91 (8%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL K SE +R R N+T S S+ Y+LG+ DRH N+ML + +G++ HIDFG
Sbjct: 2169 WL-KSKSSESWLER-RTNYTRSLGVMSMVGYILGLGDRHPSNLMLDRITGNIVHIDFGDC 2226
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMVYVI 1338
A R Y +R PF LT + Y +
Sbjct: 2227 FEVA-----MTREKYPERVPFRLTRMLTYAM 2252
Score = 38.3 bits (85), Expect = 1.6
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAG----LDLRMV 1205
SS P K++ G+D K +D+RQD V+Q+ + +TL L +
Sbjct: 2029 SSKQRPRKLSLKGSDGNAYVFCLKGHEDIRQDERVMQLFGLCNTLLTSDSESYKRHLNIQ 2088
Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAIQTEW 1235
+ A+P S + G++ V ++TL + E+
Sbjct: 2089 RYPAIPLSQNSGLLGWVPNSDTLHVLIREY 2118
>UniRef50_A2E6E9 Cluster: PIKK family atypical protein kinase; n=2;
Eukaryota|Rep: PIKK family atypical protein kinase -
Trichomonas vaginalis G3
Length = 2195
Score = 51.6 bits (118), Expect = 2e-04
Identities = 32/88 (36%), Positives = 46/88 (52%), Gaps = 8/88 (9%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
W+ NP + + + D F S A S+A Y++G+ DRH NIM+ + SGH+ HID G
Sbjct: 2005 WMKSQNP--VNWIKTVDTFVLSIALMSLAGYVVGLGDRHPSNIMIRRNSGHVVHIDLGDS 2062
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
Q KR ++ PF LT +V
Sbjct: 2063 FEVTQ-----KRTKLPEKVPFRLTRMIV 2085
>UniRef50_A6RDF6 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized
protein - Ajellomyces capsulatus NAm1
Length = 2465
Score = 51.6 bits (118), Expect = 2e-04
Identities = 61/218 (27%), Positives = 98/218 (44%), Gaps = 44/218 (20%)
Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLD-----LRMVTFQA 1209
P KI+ G+D + + K DDLR+D +++ +++ +LK ++ L + T+
Sbjct: 2143 PRKISIRGSDGNIYSLLCKPKDDLRKDQRLMEFNSMINR-FLKRDVESSKRRLYIKTYAV 2201
Query: 1210 LPTSNSKGMIEIVTEAETLRAIQT----EWGLTGS--------------------FKDKP 1245
P + G+IE V TLR + T E G+T + F +K
Sbjct: 2202 TPLNEECGLIEWVDNLRTLRELVTRLLKEKGITPNYKEIGHYLNEACADPSKLHLFTNKI 2261
Query: 1246 IA-------EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSG 1297
+A EW + P + AR +T S A S+ Y LG+ DRH +NI+ + SG
Sbjct: 2262 LAAYPPVLHEWFVEMFPEPGAWFTARLKYTRSSAVMSMVGYCLGLGDRHGENILFEENSG 2321
Query: 1298 HLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+ H+DF L D + + LV PF LT +M+
Sbjct: 2322 GVLHVDF-NCLFDKGLTFDKPELV-----PFRLTQNMI 2353
>UniRef50_A5E5B4 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 1513
Score = 51.6 bits (118), Expect = 2e-04
Identities = 67/250 (26%), Positives = 111/250 (44%), Gaps = 47/250 (18%)
Query: 1160 FIGTDNAVIPAMFKVG-DDLRQDALVLQVIKIMDTLWLKA----GLDLRMVTFQALPTS- 1213
F+ +D + +FK G DDLRQD ++ QV + ++ L+ K +L + T+ A+P
Sbjct: 1188 FLLSDGSTHRMLFKSGTDDLRQDFIMEQVFRKVNNLFKKDRECNSRNLTIRTYNAIPLGP 1247
Query: 1214 ---------NSKGMIEIV---------TEAETLRAIQTEWGLTG------SFKD-----K 1244
NS +++ + E RAI E G ++K+ K
Sbjct: 1248 NSGVIEFVPNSSALLDCIYPYHKKFDQISYEQARAIMHEAQTLGKERRIQAYKEIETKVK 1307
Query: 1245 PIAEWLAKHN-PSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHI 1302
P+ + + + + ++R N++ A S+ Y+LG+ DRH +NI+L K +G HI
Sbjct: 1308 PVLKLFFQDEFLTPDSWFQSRMNYSRGLAASSIVGYILGLGDRHCNNILLDKLTGEPIHI 1367
Query: 1303 DFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIV 1362
D G F K+L + PF LT DMV G T F + C ++
Sbjct: 1368 DLG------VAFDQGKKLPIPETVPFRLTRDMV----SGLGVTGVEGLFKKSCEHTMRVL 1417
Query: 1363 RAHHDHILDL 1372
R + +HIL +
Sbjct: 1418 RENKEHILSI 1427
>UniRef50_P42345 Cluster: FKBP12-rapamycin complex-associated protein;
n=54; Fungi/Metazoa group|Rep: FKBP12-rapamycin
complex-associated protein - Homo sapiens (Human)
Length = 2549
Score = 51.6 bits (118), Expect = 2e-04
Identities = 39/123 (31%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL K SE+ + R R N+T S A S+ Y+LG+ DRH N+ML + SG + HIDFG
Sbjct: 2304 WL-KSPSSEVWFDR-RTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDC 2361
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHD 1367
A R + ++ PF LT ++ T ++ C ++R H D
Sbjct: 2362 FEVA-----MTREKFPEKIPFRLTR----MLTNAMEVTGLDGNYRITCHTVMEVLREHKD 2412
Query: 1368 HIL 1370
++
Sbjct: 2413 SVM 2415
Score = 40.3 bits (90), Expect = 0.40
Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 1145 SCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLR- 1203
S +S P K+ +G++ + K +DLRQD V+Q+ +++TL LR
Sbjct: 2159 SLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRK 2218
Query: 1204 ---MVTFQALPTSNSKGMIEIVTEAETLRAI 1231
+ + +P S + G+I V +TL A+
Sbjct: 2219 NLSIQRYAVIPLSTNSGLIGWVPHCDTLHAL 2249
>UniRef50_Q6CT34 Cluster: Serine/threonine-protein kinase MEC1; n=1;
Kluyveromyces lactis|Rep: Serine/threonine-protein kinase
MEC1 - Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 2287
Score = 51.6 bits (118), Expect = 2e-04
Identities = 59/220 (26%), Positives = 96/220 (43%), Gaps = 41/220 (18%)
Query: 1149 FSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLK----AGLDLRM 1204
F+S P K+ IG+D + M K +D+RQD +Q M L K +L +
Sbjct: 1975 FNSLKKPKKLTVIGSDGNIYGIMCKK-EDVRQDNQYMQFANTMSFLLSKDVESRKRNLGI 2033
Query: 1205 VTFQALPTSNSKGMIEIVTEAETLRA-----------------IQTEWGLTGS------F 1241
T+ L G++EIV TLR+ +Q +W S
Sbjct: 2034 TTYGVLSLREDCGLLEIVPNVVTLRSLLSMKYESMKIKYSLKSLQEKWQSIPSDQKLAFH 2093
Query: 1242 KD-----KPIA-EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLKT 1295
KD P+ +W + P + + AR+ F S + ++ ++LG+ DRH +NI+L
Sbjct: 2094 KDCLKKFPPVLYQWFLDNFPDPITWYNARNGFVRSYSVMAMVGHILGLGDRHCENILLDV 2153
Query: 1296 -SGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDM 1334
+G + H+DF D +F K+L + PF LT ++
Sbjct: 2154 LTGRVLHVDF-----DC-LFEKGKKLPVPEIVPFRLTQNI 2187
>UniRef50_Q5EFI5 Cluster: Target of rapamycin; n=5; Poaceae|Rep:
Target of rapamycin - Zea mays (Maize)
Length = 2464
Score = 51.2 bits (117), Expect = 2e-04
Identities = 36/88 (40%), Positives = 49/88 (55%), Gaps = 8/88 (9%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL K SE+ +R R N+ S A S+ YLLG+ DRH N+ML + SG + HIDFG
Sbjct: 2197 WL-KSRTSEVWLER-RTNYARSLAVMSMVGYLLGLGDRHPSNLMLDRYSGKILHIDFGDC 2254
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+A M R + ++ PF LT +V
Sbjct: 2255 F-EASM----NREKFPEKVPFRLTRMLV 2277
Score = 40.3 bits (90), Expect = 0.40
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLW----LKAGLDLRMV 1205
+S P K+ G+D + K +DLRQD V+Q+ +++TL + DL +
Sbjct: 2057 TSKQRPRKLTIHGSDGNDYAFLLKGHEDLRQDERVMQLFGLVNTLLENSRKTSEKDLSIQ 2116
Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAIQTEW 1235
+ +P S + G+I V +TL A+ E+
Sbjct: 2117 RYAVIPLSPNSGLIGWVPNCDTLHALIREY 2146
>UniRef50_A2D9E8 Cluster: PIKK family atypical protein kinase; n=1;
Trichomonas vaginalis G3|Rep: PIKK family atypical
protein kinase - Trichomonas vaginalis G3
Length = 2207
Score = 51.2 bits (117), Expect = 2e-04
Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 19/166 (11%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
W+ NP + + R D F+ S A S++ Y++G+ DRH NIM+ + GH+ HIDFG
Sbjct: 2017 WMKSPNP--VAWLRCVDTFSLSTALMSMSGYVVGLGDRHPSNIMIQRKKGHVVHIDFGDS 2074
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHD 1367
Q R ++ PF LT +V + + Q F +C I+R +
Sbjct: 2075 FEVTQ-----TRPKMPEKVPFRLTRMIVNALGVSQTAGQ----FATMCENVLYILRKNKS 2125
Query: 1368 HI---LDLFA-LPSCDSGGSER--TVAGGRPQMSLSGV-PGVTSAA 1406
I L++F P S S+ T R M L+G+ P + S +
Sbjct: 2126 SIFAQLEIFVHEPIFASRDSQNNGTAIMNRVSMKLNGLDPSIESGS 2171
>UniRef50_Q95Q95 Cluster: Target of rapamycin homolog; n=5;
Caenorhabditis|Rep: Target of rapamycin homolog -
Caenorhabditis elegans
Length = 2697
Score = 51.2 bits (117), Expect = 2e-04
Identities = 34/88 (38%), Positives = 49/88 (55%), Gaps = 8/88 (9%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
WL K SE+ + R R N+T S A S+ Y+LG+ DRH N+ML + +G + HIDFG
Sbjct: 2481 WL-KSPSSEVWFDR-RTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDC 2538
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
A + R + +R PF LT ++
Sbjct: 2539 FEVAML-----REKFPERVPFRLTRMLI 2561
>UniRef50_P38111 Cluster: Serine/threonine-protein kinase MEC1; n=3;
Saccharomycetales|Rep: Serine/threonine-protein kinase
MEC1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 2368
Score = 51.2 bits (117), Expect = 2e-04
Identities = 61/221 (27%), Positives = 98/221 (44%), Gaps = 41/221 (18%)
Query: 1149 FSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLK----AGLDLRM 1204
FSS P ++N IG+D + M K +D+RQD +Q MD L K L +
Sbjct: 2056 FSSLKKPKQLNIIGSDGNIYGIMCKK-EDVRQDNQYMQFATTMDFLLSKDIASRKRSLGI 2114
Query: 1205 VTFQALPTSNSKGMIEIVTEAETLR-----------------AIQTEWGLT---GSFK-- 1242
+ L G++E+V TLR ++ W T G +
Sbjct: 2115 NIYSVLSLREDCGILEMVPNVVTLRSILSTKYESLKIKYSLKSLHDRWQHTAVDGKLEFY 2174
Query: 1243 ----DK--PIA-EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLK- 1294
DK PI +W ++ P + + AR+ + S A ++ ++LG+ DRH +NI+L
Sbjct: 2175 MEQVDKFPPILYQWFLENFPDPINWFNARNTYARSYAVMAMVGHILGLGDRHCENILLDI 2234
Query: 1295 TSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
+G + H+DF D +F KRL + PF LT +++
Sbjct: 2235 QTGKVLHVDF-----DC-LFEKGKRLPVPEIVPFRLTPNLL 2269
>UniRef50_Q75DB8 Cluster: Serine/threonine-protein kinase MEC1; n=2;
Eremothecium gossypii|Rep: Serine/threonine-protein
kinase MEC1 - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 2324
Score = 51.2 bits (117), Expect = 2e-04
Identities = 61/220 (27%), Positives = 95/220 (43%), Gaps = 41/220 (18%)
Query: 1149 FSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAG----LDLRM 1204
+SS P KIN IG+D + M K +D+RQD +Q +M L K L +
Sbjct: 2012 YSSLKKPKKINIIGSDGELYGIMCKK-EDVRQDNQYMQFANMMVFLLGKDSESRRRSLNI 2070
Query: 1205 VTFQALPTSNSKGMIEIVTEAET-----------------LRAIQTEW---------GLT 1238
T+ L G+IEIV +T L + +W G
Sbjct: 2071 TTYAILSLREDCGLIEIVPNVDTIRSILMAKYDSMKIKYTLSVLYEKWKSVSEEQRLGFY 2130
Query: 1239 GSFKDK--PIA-EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIMLK- 1294
S D P+ +W + P+ + + AR+ F S A ++ ++LG+ DRH +NI+L
Sbjct: 2131 KSCTDTFPPVLYQWFLETFPNPIRWYNARNAFVRSYAVMAMVGHILGLGDRHLENILLDL 2190
Query: 1295 TSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDM 1334
+G + H+DF D +F K L + PF LT ++
Sbjct: 2191 QTGKVLHVDF-----DC-LFEKGKTLPVPEIVPFRLTQNI 2224
>UniRef50_Q6BV76 Cluster: Serine/threonine-protein kinase TEL1; n=2;
Debaryomyces hansenii|Rep: Serine/threonine-protein
kinase TEL1 - Debaryomyces hansenii (Yeast) (Torulaspora
hansenii)
Length = 2948
Score = 51.2 bits (117), Expect = 2e-04
Identities = 39/108 (36%), Positives = 54/108 (50%), Gaps = 11/108 (10%)
Query: 1264 RDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNFKRLVY 1322
R ++T A S+ ++LG+ DRH +NI+L KTSG HID G F KRL
Sbjct: 2760 RTSYTRGIATTSMVGHILGLGDRHCNNILLDKTSGEPIHIDLG------VAFDQGKRLPI 2813
Query: 1323 IDRAPFVLTHDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHIL 1370
+ PF LT D+V G T F + C + ++R + DHIL
Sbjct: 2814 PETVPFRLTRDIV----DGFGITGVNGVFDKSCEHTYRVLRQNKDHIL 2857
>UniRef50_A2FZM6 Cluster: PIKK family atypical protein kinase; n=1;
Trichomonas vaginalis G3|Rep: PIKK family atypical
protein kinase - Trichomonas vaginalis G3
Length = 2159
Score = 50.8 bits (116), Expect = 3e-04
Identities = 47/163 (28%), Positives = 71/163 (43%), Gaps = 13/163 (7%)
Query: 1215 SKGMIEIVTEAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGY 1274
S V E T++ + S D + + + +PS E+ + F + A
Sbjct: 1937 SNNFTSSVDEMTTVQRYEALLTAIQSTDDNDLEKAIWMRSPSSNEWIKRTTRFAQTSAVM 1996
Query: 1275 SVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHD 1333
S+ Y+LG+ DRH N+M+ K+SG + HIDF A+ R + + PF LT
Sbjct: 1997 SIIGYILGLGDRHPSNLMMHKSSGDVIHIDFSDCFEIAK-----TREQFPEGVPFRLTRM 2051
Query: 1334 MVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHI---LDLF 1373
MV G R F+ E IVR+H + I LD+F
Sbjct: 2052 MVRAF-GPARIEGNFRIAAE---EMMKIVRSHRESIMTVLDIF 2090
Score = 40.3 bits (90), Expect = 0.40
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRM-----VTFQA 1209
P I F G+D ++ K +DLR D V+Q ++M+ L +K G + RM TF
Sbjct: 1837 PRIIVFHGSDGKPHRSLLKGHEDLRLDQRVMQFFQLMN-LHIKNGPNTRMRNLALHTFAI 1895
Query: 1210 LPTSNSKGMIEIVTEAETLRAIQTEW 1235
P SN G+I+ + + +T + T +
Sbjct: 1896 TPISNRSGIIQFIDDTDTFNQLITSY 1921
>UniRef50_A2DII8 Cluster: PIKK family atypical protein kinase; n=2;
Eukaryota|Rep: PIKK family atypical protein kinase -
Trichomonas vaginalis G3
Length = 2194
Score = 50.8 bits (116), Expect = 3e-04
Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
W + ++ AR N+T S A +S+ Y++G+ DRH +NI+ KT+G + H+DF
Sbjct: 2004 WFLDNFKDASQWFVARQNYTRSTAVWSMVGYIVGLGDRHLENILFNKTNGSVVHVDF--- 2060
Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
MF K L + PF LT ++V
Sbjct: 2061 ---CYMFDKAKTLPTPECVPFRLTQNVV 2085
>UniRef50_UPI00015B5AD2 Cluster: PREDICTED: similar to fkbp-rapamycin
associated protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to fkbp-rapamycin associated protein -
Nasonia vitripennis
Length = 2467
Score = 50.4 bits (115), Expect = 4e-04
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 3/58 (5%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFG 1305
WL K SE+ + R R N+T S A S+ Y+LG+ DRH N+ML + SG + HIDFG
Sbjct: 2226 WL-KSPSSEVWFDR-RTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFG 2281
>UniRef50_UPI0000D56D93 Cluster: PREDICTED: similar to CG5092-PA; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to CG5092-PA
- Tribolium castaneum
Length = 2400
Score = 50.4 bits (115), Expect = 4e-04
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 3/58 (5%)
Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFG 1305
WL K SE+ + R R N+T S A S+ Y+LG+ DRH N+ML + SG + HIDFG
Sbjct: 2170 WL-KSPSSEVWFDR-RTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFG 2225
Score = 35.9 bits (79), Expect = 8.5
Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Query: 1144 KSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLK----AG 1199
+S +S P K+ G++ + K +DLRQD V+Q+ +++TL +K
Sbjct: 2024 RSLEVITSKQRPRKLVIRGSNGKDYMFLLKGHEDLRQDERVMQLFGLVNTLLMKDPDTFR 2083
Query: 1200 LDLRMVTFQALPTSNSKGMIEIVTEAETLRAI 1231
+L + + +P S + G+I + +TL +
Sbjct: 2084 RNLTIQRYAVIPLSTNSGLIGWLPHCDTLHTL 2115
>UniRef50_A2ESW1 Cluster: PIKK family atypical protein kinase; n=1;
Trichomonas vaginalis G3|Rep: PIKK family atypical
protein kinase - Trichomonas vaginalis G3
Length = 2200
Score = 50.4 bits (115), Expect = 4e-04
Identities = 34/119 (28%), Positives = 56/119 (47%), Gaps = 6/119 (5%)
Query: 1224 EAETLRAIQTEWGLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGI 1283
+ L+ ++ + D + E L +P+ + FT S A S+A Y++G+
Sbjct: 1986 QLNALQKVEVYQAVCKGSSDGELRETLWLKSPTPSAWVERSYQFTVSTALMSMAGYVIGL 2045
Query: 1284 CDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGG 1341
DRH NIM+ + +G + HIDFG + F LV PF LT ++ ++GG
Sbjct: 2046 GDRHPSNIMIQRHTGRVIHIDFGDSFEVTRQRPLFPELV-----PFRLTRMIISALDGG 2099
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.319 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,494,433,137
Number of Sequences: 1657284
Number of extensions: 57321832
Number of successful extensions: 122184
Number of sequences better than 10.0: 396
Number of HSP's better than 10.0 without gapping: 254
Number of HSP's successfully gapped in prelim test: 142
Number of HSP's that attempted gapping in prelim test: 120878
Number of HSP's gapped (non-prelim): 975
length of query: 1505
length of database: 575,637,011
effective HSP length: 110
effective length of query: 1395
effective length of database: 393,335,771
effective search space: 548703400545
effective search space used: 548703400545
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 79 (35.9 bits)
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