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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001268-TA|BGIBMGA001268-PA|IPR011009|Protein
kinase-like, IPR008973|C2 calcium/lipid-binding region, CaLB,
IPR000403|Phosphatidylinositol 3- and 4-kinase, catalytic,
IPR000341|Phosphoinositide 3-kinase, ras-binding,
IPR002420|Phosphoinositide 3-kinase, C2, IPR001263|Phosphoinositide
3-kinase accessory region PIK, IPR001683|Phox-like
         (1505 letters)

Database: spombe 
           5004 sequences; 2,362,478 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SPAC458.05 |pik3|vps34|phosphatidylinositol 3-kinase Pik3|Schizo...   139   3e-33
SPBC577.06c |||phosphatidylinositol kinase |Schizosaccharomyces ...   120   1e-27
SPAC22E12.16c |pik1||phosphatidylinositol kinase Pik1|Schizosacc...    93   3e-19
SPBC216.05 |rad3||ATR checkpoint kinase|Schizosaccharomyces pomb...    50   3e-06
SPCC23B6.03c |tel1||ATM checkpoint kinase|Schizosaccharomyces po...    46   3e-05
SPBC216.07c |tor2|SPBC646.01c|phosphatidylinositol kinase Tor2|S...    46   5e-05
SPBC30D10.10c |tor1||phosphatidylinositol kinase Tor1|Schizosacc...    46   5e-05
SPCC1322.14c |vtc4||vacuolar transporter chaperone |Schizosaccha...    31   0.93 

>SPAC458.05 |pik3|vps34|phosphatidylinositol 3-kinase
            Pik3|Schizosaccharomyces pombe|chr 1|||Manual
          Length = 801

 Score =  139 bits (336), Expect = 3e-33
 Identities = 136/505 (26%), Positives = 218/505 (43%), Gaps = 46/505 (9%)

Query: 882  QSQLLHLIEQGAYQRMPTECREVMWEKRQYLVQIPGALPLVLLAATNWYGDHREQLIGLL 941
            + +L  ++     + +  E ++++W+ R YL +   A+   L +          Q + LL
Sbjct: 267  RKELESILSYPPSEELSLEEKDLIWKFRFYLTRNKKAMTKFLKSVVWTDSSEVNQALSLL 326

Query: 942  RLWEKPSPLNAMHLLLPCFPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXX 1001
              W +    +A+ LL P F    VR  A   L   S+++L   L  L Q ++   Y    
Sbjct: 327  DSWTEIDIDDALELLSPSFVHPKVRAYAVSRLETASNEEL---LLYLLQLVQALRYDNPI 383

Query: 1002 XXXXXXXXXXXXXXXXXXXFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSAS 1061
                                     S P+I    +  +L + +ED      E  + + +S
Sbjct: 384  SSDERFQPSPLALFLVNRAI-----SSPSIGNDLYW-YLVVEIED------EPVSKLFSS 431

Query: 1062 WRYTLMLRALLVICGENLNKTLLRQQLLVKSLCEMAVSVKCAKEXXXXXXXXXXXXXXXX 1121
              +         + G  + +TL  Q   V+ L  ++ SV+  +                 
Sbjct: 432  VMFLFQKELSKSVEGRLIRETLSAQAKFVEKLLRISKSVQSFRGTRLKKIEYLKVLLEDH 491

Query: 1122 XXXXQPT-ALPLALHKYVHDLDV--KSCTYFSSNTLPLKINFIGTDNAVIPAMFKVGDDL 1178
                    ALPL L   V+ + +   +CT F S   PL++ F   D +  P +FK GDDL
Sbjct: 492  KYHLLDFHALPLPLDPSVNIVGIIPDACTVFKSTMQPLRLLFKCQDGSKYPIIFKNGDDL 551

Query: 1179 RQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLRAIQTEWGLT 1238
            RQD LV+Q++ +MD L  K  LDL +  ++ L T  + G ++ V  ++TL  I  E+   
Sbjct: 552  RQDQLVIQILTLMDKLLKKEKLDLHLKPYRILATGPTHGAVQFVP-SKTLATILAEYH-- 608

Query: 1239 GSFKDKPIAEWLAKHNPSE----LEY---QRARDNFTASCAGYSVATYLLGICDRHNDNI 1291
            GS     +  +L ++NP +      Y     A DN+  SCAGY V TYLLG+ DRH DN+
Sbjct: 609  GS-----VLAYLRENNPDDGLNSANYGIDPVAMDNYVRSCAGYCVITYLLGVGDRHLDNL 663

Query: 1292 MLKTSGHLFHIDFGKFLG-DAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQRFQH 1350
            ++   GH FH DFG  LG D ++F    +          L+ +MV  + G   P   +Q 
Sbjct: 664  LITKDGHFFHADFGYILGRDPKLFSPAMK----------LSKEMVEGMGGYNSPF--YQQ 711

Query: 1351 FVELCCMAFNIVRAHHDHILDLFAL 1375
            F   C   F  +R   + IL+LF+L
Sbjct: 712  FKSYCYTTFTALRKSSNLILNLFSL 736


>SPBC577.06c |||phosphatidylinositol kinase |Schizosaccharomyces
            pombe|chr 2|||Manual
          Length = 1877

 Score =  120 bits (290), Expect = 1e-27
 Identities = 77/202 (38%), Positives = 108/202 (53%), Gaps = 16/202 (7%)

Query: 1170 AMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAETLR 1229
            A+FKVGDD RQD L LQ+I +   ++   GLD+ +  ++   T+   G+I+++    +  
Sbjct: 1621 AIFKVGDDCRQDVLTLQLIAMFKNIFNSVGLDVYLFPYRVTATNPGCGVIDVLPNCISRD 1680

Query: 1230 AIQTEW--GLTGSFKDKPIAEWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRH 1287
             +  E   GL   F+ K   E         + +Q+AR NF  S A YSV TYLL   DRH
Sbjct: 1681 MLGREAVNGLYDYFRTKFGDE-------DSIAFQKARSNFVQSMAAYSVITYLLQFKDRH 1733

Query: 1288 NDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLTHDMVYVINGGERPTQR 1347
            N NIM+   GH+ HIDFG F+ D    G     +  + APF LT +M+ V+ GG   +Q 
Sbjct: 1734 NGNIMIDDQGHILHIDFG-FIFDIAPGG-----ITFESAPFKLTTEMIAVM-GGSNKSQP 1786

Query: 1348 FQHFVELCCMAFNIVRAHHDHI 1369
            FQ F ELC  AF   R +  +I
Sbjct: 1787 FQWFQELCVKAFLACRPYAHYI 1808


>SPAC22E12.16c |pik1||phosphatidylinositol kinase
            Pik1|Schizosaccharomyces pombe|chr 1|||Manual
          Length = 851

 Score = 93.1 bits (221), Expect = 3e-19
 Identities = 65/219 (29%), Positives = 109/219 (49%), Gaps = 29/219 (13%)

Query: 1167 VIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDLRMVTFQALPTSNSKGMIEIVTEAE 1226
            ++  + K G DLRQ+    Q+I     +WL+    + +   + L T ++ G+IE +T A 
Sbjct: 578  LVSVIVKTGADLRQETFACQLIYAFQRVWLECKEKVWVRRMKILVTGDNSGLIETITNAI 637

Query: 1227 TLRAIQTEWGLTGSFKDKPIAEW-LAKHN--------------PSELEYQRARDNFTASC 1271
            ++ +I+    LT   ++  +A+  +A  N              P+   Y++A+ NF  S 
Sbjct: 638  SVHSIKKN--LTKQLREAELAQGKIAGKNVVTLKDYFIKQFGDPNSSRYRQAQTNFLQSL 695

Query: 1272 AGYSVATYLLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRLVYIDRAPFVLT 1331
              YS+ +YLL + DRHN N+++ + GH+ HIDFG  L +    GN    V  + APF LT
Sbjct: 696  VAYSIISYLLQLKDRHNGNVLIDSEGHIIHIDFGFLLTNTP--GN----VGFESAPFKLT 749

Query: 1332 HDMVYVINGGERPTQRFQHFVELCCMAFNIVRAHHDHIL 1370
             D + +++       RF  +  L   AF  VR + D I+
Sbjct: 750  ADYLEILD------DRFDEYRSLMKAAFKSVRKNADQII 782


>SPBC216.05 |rad3||ATR checkpoint kinase|Schizosaccharomyces pombe|chr
            2|||Manual
          Length = 2386

 Score = 49.6 bits (113), Expect = 3e-06
 Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 7/89 (7%)

Query: 1248 EWLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGK 1306
            EW  +  P    +  +R N+  + A  S+  Y+LG+ DRH +NI+  + +G   H+DF  
Sbjct: 2193 EWFVESFPEPNNWVTSRQNYCRTLAVMSIVGYVLGLGDRHGENILFDEFTGEAIHVDFNC 2252

Query: 1307 FLGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
                   F         ++ PF LTH+MV
Sbjct: 2253 LFDKGLTFEK------PEKVPFRLTHNMV 2275



 Score = 34.3 bits (75), Expect = 0.13
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 1155 PLKINFIGTDNAVIPAMFKVGDDLRQDALVLQ----VIKIMDTLWLKAGLDLRMVTFQAL 1210
            P K+   GTD  + P + K  DDLR+DA +++    + KI+         +L + T+  +
Sbjct: 2065 PRKVYVRGTDGNLYPFLCKPKDDLRKDARLMEFNNLICKILRKDQEANRRNLCIRTYVVI 2124

Query: 1211 PTSNSKGMIEIVTEAETLRAI 1231
            P +   G IE V      R I
Sbjct: 2125 PLNEECGFIEWVNHTRPFREI 2145


>SPCC23B6.03c |tel1||ATM checkpoint kinase|Schizosaccharomyces
            pombe|chr 3|||Manual
          Length = 2812

 Score = 46.4 bits (105), Expect = 3e-05
 Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 7/79 (8%)

Query: 1258 LEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKFLGDAQMFGN 1316
            +++   + N+  S A  SV  ++LG+ DRH  NI++ KTSG + HID G        F  
Sbjct: 2603 VQWFTTQTNYARSTAVASVLGHVLGLGDRHGQNILIDKTSGEVIHIDLG------IAFEQ 2656

Query: 1317 FKRLVYIDRAPFVLTHDMV 1335
             K+L   +  PF LT D+V
Sbjct: 2657 GKKLPVPECVPFRLTRDVV 2675



 Score = 30.7 bits (66), Expect = 1.6
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 5/82 (6%)

Query: 1148 YFSSNTLPLKINFIGTDNAVIPAMFKVG-DDLRQDALVLQVIK----IMDTLWLKAGLDL 1202
            + S    P  I  +G++      + K G DDLRQDA++ QV +     + +    +  +L
Sbjct: 2455 FASGINAPKVITCLGSNGHTYKQLVKGGNDDLRQDAVMEQVFEQVNGFLRSYRKTSQRNL 2514

Query: 1203 RMVTFQALPTSNSKGMIEIVTE 1224
             M T++ +P +   G+IE V +
Sbjct: 2515 SMRTYKVIPLALKTGVIEWVQD 2536


>SPBC216.07c |tor2|SPBC646.01c|phosphatidylinositol kinase
            Tor2|Schizosaccharomyces pombe|chr 2|||Manual
          Length = 2337

 Score = 45.6 bits (103), Expect = 5e-05
 Identities = 32/88 (36%), Positives = 47/88 (53%), Gaps = 8/88 (9%)

Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFGKF 1307
            WL K   SE    R R N++ + A  S+  Y+LG+ DRH  N+ML + +G++ HIDFG  
Sbjct: 2106 WL-KSRSSEAWLNR-RTNYSRTLAVMSMVGYILGLGDRHPSNLMLDRYTGNIIHIDFGDC 2163

Query: 1308 LGDAQMFGNFKRLVYIDRAPFVLTHDMV 1335
               A       R  + ++ PF LT  +V
Sbjct: 2164 FEVA-----MHREKFPEKIPFRLTRMLV 2186



 Score = 31.9 bits (69), Expect = 0.70
 Identities = 21/86 (24%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAGLDL-RMVTFQ 1208
            +S   P +++  G+D      + K  +D+RQD  V+Q+  + + L L       R+++ Q
Sbjct: 1966 TSKQRPRRLSIKGSDGKDYQYVLKGHEDIRQDERVMQLFGLCNNLLLADPETFKRLLSIQ 2025

Query: 1209 ---ALPTSNSKGMIEIVTEAETLRAI 1231
                +P S   G++  V +++TL  +
Sbjct: 2026 RYPVIPLSPDSGLLGWVLDSDTLHVL 2051


>SPBC30D10.10c |tor1||phosphatidylinositol kinase
            Tor1|Schizosaccharomyces pombe|chr 2|||Manual
          Length = 2335

 Score = 45.6 bits (103), Expect = 5e-05
 Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 3/58 (5%)

Query: 1249 WLAKHNPSELEYQRARDNFTASCAGYSVATYLLGICDRHNDNIML-KTSGHLFHIDFG 1305
            WL K   SE    R R ++T S A  S+  Y+LG+ DRH  N+M+ + SG + HIDFG
Sbjct: 2103 WL-KSRSSEAWLDR-RTSYTQSLAVMSMVGYILGLGDRHPSNLMMDRYSGKIIHIDFG 2158



 Score = 33.5 bits (73), Expect = 0.23
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1150 SSNTLPLKINFIGTDNAVIPAMFKVGDDLRQDALVLQVIKIMDTLWLKAG----LDLRMV 1205
            SS   P ++   G+D      + K  +DLRQD  V+Q+  + +TL           L + 
Sbjct: 1963 SSKQRPRRLTIHGSDGKDYQYVLKGHEDLRQDERVMQLFGLCNTLLTTDSETFKRRLNIE 2022

Query: 1206 TFQALPTSNSKGMIEIVTEAETLRAIQTEW 1235
             +  +P S + G++  V  ++TL  +  E+
Sbjct: 2023 RYTVIPLSPNSGLLGWVPHSDTLHFLIKEF 2052


>SPCC1322.14c |vtc4||vacuolar transporter chaperone
           |Schizosaccharomyces pombe|chr 3|||Manual
          Length = 721

 Score = 31.5 bits (68), Expect = 0.93
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 276 PLLTEQSNPEYAVGSECSSSVYEEYDPLDFLYGETEMRE 314
           P+L    N E+A      +S+Y + D LDF  G  E RE
Sbjct: 218 PVLVFNPNKEFAREDAAITSIYYDNDDLDFYLGRLEKRE 256


  Database: spombe
    Posted date:  Oct 3, 2007  3:31 PM
  Number of letters in database: 2,362,478
  Number of sequences in database:  5004
  
Lambda     K      H
   0.319    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 6,142,226
Number of Sequences: 5004
Number of extensions: 239163
Number of successful extensions: 588
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 565
Number of HSP's gapped (non-prelim): 15
length of query: 1505
length of database: 2,362,478
effective HSP length: 82
effective length of query: 1423
effective length of database: 1,952,150
effective search space: 2777909450
effective search space used: 2777909450
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 60 (28.3 bits)

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