Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001267-TA|BGIBMGA001267-PA|IPR000569|HECT
(910 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB194232-2|BAD69554.1| 852|Homo sapiens ubiquitin ligase E3A is... 694 0.0
U84404-1|AAB49301.1| 852|Homo sapiens E6-associated protein E6-... 691 0.0
AF273050-1|AAG34910.1| 852|Homo sapiens CTCL tumor antigen se37... 691 0.0
AF016708-1|AAB69154.1| 852|Homo sapiens E6-AP ubiquitin-protein... 691 0.0
X98033-1|CAA66656.1| 852|Homo sapiens E6-AP protein. 690 0.0
X98032-1|CAA66655.1| 852|Homo sapiens E6-AP protein. 690 0.0
X98031-1|CAA66654.1| 852|Homo sapiens E6-AP protein. 690 0.0
X98021-1|CAA66653.1| 852|Homo sapiens E6-AP protein. 690 0.0
BC002582-1|AAH02582.2| 872|Homo sapiens ubiquitin protein ligas... 688 0.0
BC009271-1|AAH09271.1| 585|Homo sapiens UBE3A protein protein. 679 0.0
L07557-1|AAA35542.1| 874|Homo sapiens oncogenic protein-associa... 677 0.0
AL161798-4|CAH70053.1| 776|Homo sapiens HECT domain containing ... 350 1e-95
BC040187-1|AAH40187.1| 776|Homo sapiens HECT domain containing ... 349 3e-95
AL161798-1|CAH70050.1| 426|Homo sapiens HECT domain containing ... 339 3e-92
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p... 306 2e-82
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p... 306 2e-82
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p... 306 2e-82
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin... 303 2e-81
AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4 p... 303 2e-81
AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4 p... 303 2e-81
AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein. 303 2e-81
D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein. 299 4e-80
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas... 243 2e-63
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei... 243 2e-63
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p... 228 8e-59
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein. 228 8e-59
BC035775-1|AAH35775.2| 396|Homo sapiens HERC6 protein protein. 227 1e-58
AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant pr... 227 1e-58
AK000644-1|BAA91303.1| 379|Homo sapiens protein ( Homo sapiens ... 227 1e-58
AL713675-1|CAD28480.1| 238|Homo sapiens hypothetical protein pr... 213 2e-54
AJ001108-1|CAA04535.1| 415|Homo sapiens E6-AP ubiquitin-protein... 209 3e-53
Z97054-12|CAI42656.1| 3407|Homo sapiens upstream regulatory elem... 206 3e-52
Z97054-10|CAI42654.1| 4374|Homo sapiens upstream regulatory elem... 206 3e-52
Z97054-1|CAI42644.1| 1196|Homo sapiens upstream regulatory eleme... 206 3e-52
Z94044-4|CAI42354.1| 4374|Homo sapiens upstream regulatory eleme... 206 3e-52
DQ097177-1|AAY98258.1| 4374|Homo sapiens Mcl-1 ubiquitin ligase ... 206 3e-52
BC063505-1|AAH63505.1| 388|Homo sapiens HUWE1 protein protein. 206 3e-52
AY929612-1|AAX24125.1| 4374|Homo sapiens LASU1 protein. 206 3e-52
AY772009-1|AAV90838.1| 4374|Homo sapiens ARF-binding protein 1 p... 206 3e-52
AL592046-4|CAI39581.1| 3407|Homo sapiens upstream regulatory ele... 206 3e-52
AL592046-3|CAI39580.1| 4374|Homo sapiens upstream regulatory ele... 206 3e-52
AL592046-1|CAI39578.1| 1196|Homo sapiens upstream regulatory ele... 206 3e-52
AB071605-1|BAC06833.1| 3360|Homo sapiens HECT domain protein LAS... 206 3e-52
AB002310-1|BAA20771.2| 3192|Homo sapiens KIAA0312 protein. 206 3e-52
AK223167-1|BAD96887.1| 439|Homo sapiens E3 ubiquitin protein li... 206 4e-52
BC002602-1|AAH02602.2| 442|Homo sapiens HUWE1 protein protein. 203 2e-51
D42055-1|BAA07655.1| 927|Homo sapiens KIAA0093 protein. 200 2e-50
AY550969-1|AAT52215.1| 900|Homo sapiens cell proliferation-indu... 200 2e-50
AF464850-1|AAM90910.1| 757|Homo sapiens Smad-ubiquitin E3 ligas... 200 2e-50
AF199364-1|AAF08298.2| 722|Homo sapiens E3 ubiquitin ligase SMU... 200 2e-50
AC004893-2|AAC62434.1| 712|Homo sapiens WUGSC:H_DJ0808A01.2 pro... 200 2e-50
AB046845-1|BAB13451.1| 859|Homo sapiens KIAA1625 protein protein. 200 2e-50
U96114-1|AAC51325.1| 870|Homo sapiens WWP2 protein. 199 4e-50
BC064531-1|AAH64531.1| 870|Homo sapiens WWP2 protein protein. 199 4e-50
BC013645-1|AAH13645.1| 870|Homo sapiens WW domain containing E3... 199 4e-50
BC011571-1|AAH11571.1| 903|Homo sapiens ITCH protein protein. 199 4e-50
AL356299-4|CAI17960.1| 862|Homo sapiens itchy homolog E3 ubiqui... 199 4e-50
AL356299-3|CAI17959.1| 903|Homo sapiens itchy homolog E3 ubiqui... 199 4e-50
AL109923-6|CAI21458.1| 903|Homo sapiens itchy homolog E3 ubiqui... 199 4e-50
AL109923-5|CAI21459.1| 862|Homo sapiens itchy homolog E3 ubiqui... 199 4e-50
AF095745-1|AAK39399.1| 862|Homo sapiens ubiquitin protein ligas... 199 4e-50
AF038564-1|AAC04845.1| 739|Homo sapiens atrophin-1 interacting ... 199 4e-50
AB209747-1|BAD92984.1| 605|Homo sapiens itchy homolog E3 ubiqui... 199 4e-50
AB056663-1|BAB39389.1| 862|Homo sapiens ubiquitin protein ligas... 199 4e-50
BC111945-1|AAI11946.1| 748|Homo sapiens SMAD specific E3 ubiqui... 195 7e-49
BC093876-1|AAH93876.1| 748|Homo sapiens SMAD specific E3 ubiqui... 195 7e-49
AY014180-1|AAG50421.1| 748|Homo sapiens E3 ubiquitin ligase Smu... 195 7e-49
AF310676-1|AAG45422.1| 748|Homo sapiens E3 ubiquitin ligase SMU... 195 7e-49
AF301463-1|AAG25641.1| 748|Homo sapiens ubiquitin E3 ligase SMU... 195 7e-49
DQ181796-1|ABA10330.1| 834|Homo sapiens NEDD4L variant protein. 194 9e-49
BC032597-1|AAH32597.1| 911|Homo sapiens NEDD4L protein protein. 194 9e-49
BC019345-1|AAH19345.1| 855|Homo sapiens Unknown (protein for IM... 194 9e-49
BC000621-1|AAH00621.2| 855|Homo sapiens NEDD4L protein protein. 194 9e-49
AY312514-1|AAP75706.1| 975|Homo sapiens NEDD4.2 protein. 194 9e-49
AY112985-1|AAM76730.1| 947|Homo sapiens ubiquitin ligase NEDD4h... 194 9e-49
AY112984-1|AAM76729.1| 967|Homo sapiens ubiquitin ligase NEDD4g... 194 9e-49
AY112983-1|AAM76728.1| 854|Homo sapiens ubiquitin ligase NEDD4f... 194 9e-49
AL137469-1|CAB70754.1| 820|Homo sapiens hypothetical protein pr... 194 9e-49
AF385931-1|AAM46208.1| 854|Homo sapiens ubiquitin ligase NEDD4L... 194 9e-49
AF210730-1|AAG43524.1| 854|Homo sapiens NEDD4La protein. 194 9e-49
AB071179-1|BAB69424.1| 955|Homo sapiens NEDD4-like ubiquitin li... 194 9e-49
AB007899-1|BAA23711.1| 995|Homo sapiens KIAA0439 protein. 194 9e-49
BC107576-1|AAI07577.1| 332|Homo sapiens HUWE1 protein protein. 193 2e-48
BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin... 189 3e-47
AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin... 189 3e-47
AL590402-1|CAH74023.1| 562|Homo sapiens HECT domain and ankyrin... 189 3e-47
AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin... 189 3e-47
AL513472-1|CAH71889.1| 562|Homo sapiens HECT domain and ankyrin... 189 3e-47
AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin... 189 3e-47
AB037741-1|BAA92558.1| 567|Homo sapiens KIAA1320 protein protein. 189 3e-47
BC036065-1|AAH36065.1| 922|Homo sapiens WW domain containing E3... 184 1e-45
AY345857-1|AAQ22764.1| 922|Homo sapiens TGIF-interacting ubiqui... 184 1e-45
AY043361-1|AAK94668.1| 922|Homo sapiens WW domain-containing pr... 184 1e-45
BC117198-1|AAI17199.1| 1572|Homo sapiens HECT, C2 and WW domain ... 183 3e-45
BC117194-1|AAI17195.1| 1572|Homo sapiens HECT, C2 and WW domain ... 183 3e-45
AB037722-1|BAA92539.1| 1581|Homo sapiens KIAA1301 protein protein. 183 3e-45
AB048365-1|BAB13352.1| 1585|Homo sapiens NEDD4-like ubiquitin li... 179 4e-44
AB002320-1|BAA20780.2| 1614|Homo sapiens KIAA0322 protein. 179 4e-44
AC004975-1|AAD51453.1| 415|Homo sapiens unknown protein. 175 6e-43
D13635-1|BAA02799.2| 1086|Homo sapiens KIAA0010 protein. 173 3e-42
CR456813-1|CAG33094.1| 308|Homo sapiens UREB1 protein. 169 4e-41
AF057569-1|AAC62492.1| 308|Homo sapiens upstream regulatory ele... 169 4e-41
AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containin... 162 6e-39
U96113-1|AAC51324.1| 684|Homo sapiens WWP1 protein. 154 2e-36
BC009527-1|AAH09527.1| 288|Homo sapiens SMURF2 protein protein. 147 2e-34
BC015380-1|AAH15380.2| 300|Homo sapiens WWP1 protein protein. 146 4e-34
BC141880-1|AAI41881.1| 1068|Homo sapiens ubiquitin protein ligas... 138 8e-32
AF251046-1|AAK28419.2| 1068|Homo sapiens UBE3B variant 1 protein. 138 8e-32
AC007956-1|AAF61276.1| 823|Homo sapiens KIAA0317 protein. 128 1e-28
AB002315-1|BAA20775.2| 826|Homo sapiens KIAA0317 protein. 128 1e-28
AK126332-1|BAC86528.1| 343|Homo sapiens protein ( Homo sapiens ... 124 2e-27
BC032301-1|AAH32301.1| 1026|Homo sapiens Unknown (protein for IM... 123 2e-27
BX537403-1|CAD97645.1| 1068|Homo sapiens hypothetical protein pr... 122 8e-27
AJ001112-1|CAA04539.1| 76|Homo sapiens E6-AP ubiquitin-protein... 113 4e-24
D28476-1|BAA05837.2| 2005|Homo sapiens KIAA0045 protein. 108 1e-22
BC114556-1|AAI14557.1| 2040|Homo sapiens TRIP12 protein protein. 108 1e-22
BC113891-1|AAI13892.1| 1722|Homo sapiens TRIP12 protein protein. 108 1e-22
AC093384-2|AAY14681.1| 1299|Homo sapiens unknown protein. 108 1e-22
AJ001110-1|CAA04537.1| 68|Homo sapiens E6-AP ubiquitin-protein... 107 2e-22
BC063686-1|AAH63686.1| 347|Homo sapiens HECTD1 protein protein. 106 3e-22
BC011658-1|AAH11658.2| 520|Homo sapiens HECTD1 protein protein. 106 3e-22
AY739714-1|AAW65983.1| 1224|Homo sapiens HECTD1 protein. 106 3e-22
AY254380-1|AAP13073.1| 2612|Homo sapiens E3 ligase for inhibin r... 106 3e-22
AL110222-1|CAB53681.1| 959|Homo sapiens hypothetical protein pr... 106 3e-22
AB032957-1|BAA86445.2| 2168|Homo sapiens KIAA1131 protein protein. 106 3e-22
L40383-1|AAC41731.1| 174|Homo sapiens thyroid receptor interact... 103 4e-21
BC032944-1|AAH32944.1| 789|Homo sapiens KIAA0317 protein protein. 103 4e-21
U95000-1|AAF88143.1| 2798|Homo sapiens hyd protein protein. 100 2e-20
AF006010-1|AAD01259.2| 2799|Homo sapiens progestin induced prote... 100 2e-20
AB020703-1|BAA74919.3| 2820|Homo sapiens KIAA0896 protein protein. 100 2e-20
AL834183-1|CAD38880.1| 523|Homo sapiens hypothetical protein pr... 92 7e-18
AF225409-1|AAO27484.1| 306|Homo sapiens HERC2 protein. 92 7e-18
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein. 92 7e-18
AJ001109-1|CAA04536.1| 48|Homo sapiens E6-AP ubiquitin-protein... 88 1e-16
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein. 87 4e-16
BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein. 87 4e-16
BC083494-1|AAH83494.1| 171|Homo sapiens HECTD1 protein protein. 83 3e-15
BC130470-1|AAI30471.1| 577|Homo sapiens HECT domain containing ... 78 1e-13
BC126352-1|AAI26353.1| 577|Homo sapiens HECT domain containing ... 78 1e-13
AL359473-2|CAI16438.1| 861|Homo sapiens HECT domain containing ... 78 1e-13
AL359473-1|CAI16437.1| 471|Homo sapiens HECT domain containing ... 78 1e-13
BC006848-1|AAH06848.1| 118|Homo sapiens Similar to RIKEN cDNA 1... 75 9e-13
AJ001113-1|CAA04540.1| 39|Homo sapiens E6-AP ubiquitin-protein... 69 6e-11
AF009341-1|AAC39580.1| 39|Homo sapiens E6-AP ubiquitin-protein... 69 6e-11
AJ001107-1|CAA04534.1| 99|Homo sapiens E6-AP ubiquitin-protein... 68 1e-10
BC019105-1|AAH19105.1| 210|Homo sapiens HECTD3 protein protein. 65 1e-09
AK024809-1|BAB15015.1| 210|Homo sapiens protein ( Homo sapiens ... 65 1e-09
AJ001111-1|CAA04538.1| 55|Homo sapiens E6-AP ubiquitin-protein... 57 2e-07
BC006237-1|AAH06237.2| 121|Homo sapiens HECTD1 protein protein. 55 1e-06
AF174498-1|AAF36539.1| 1381|Homo sapiens GR AF-1 specific protei... 45 0.001
BC021144-1|AAH21144.1| 740|Homo sapiens FLJ30092 protein protein. 44 0.002
AB014514-1|BAA31589.3| 3006|Homo sapiens KIAA0614 protein protein. 44 0.002
BC006270-1|AAH06270.2| 274|Homo sapiens FLJ30092 protein protein. 43 0.006
BC044598-1|AAH44598.1| 79|Homo sapiens EDD1 protein protein. 42 0.010
X54890-1|CAA38662.1| 793|Homo sapiens protein-tyrosine phosphat... 36 0.49
X54130-1|CAA38065.1| 793|Homo sapiens protein-tyrosine phosphat... 36 0.49
X53364-1|CAA37447.1| 793|Homo sapiens tyrosine phosphatase prec... 36 0.49
M34668-1|AAA36528.1| 802|Homo sapiens protein ( Human protein t... 36 0.49
BC027308-1|AAH27308.1| 793|Homo sapiens protein tyrosine phosph... 36 0.49
AL121905-6|CAC10336.1| 802|Homo sapiens protein tyrosine phosph... 36 0.49
AL121905-5|CAC10337.1| 793|Homo sapiens protein tyrosine phosph... 36 0.49
AL121905-4|CAI21711.1| 253|Homo sapiens protein tyrosine phosph... 36 0.49
AL121905-3|CAI21710.1| 200|Homo sapiens protein tyrosine phosph... 36 0.49
AL121905-2|CAI21709.1| 175|Homo sapiens protein tyrosine phosph... 36 0.49
AL121905-1|CAI21708.1| 138|Homo sapiens protein tyrosine phosph... 36 0.49
X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mR... 32 8.0
BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase, cAMP-de... 32 8.0
BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein. 32 8.0
>AB194232-2|BAD69554.1| 852|Homo sapiens ubiquitin ligase E3A
isoform 1 protein.
Length = 852
Score = 694 bits (1714), Expect = 0.0
Identities = 385/883 (43%), Positives = 529/883 (59%), Gaps = 43/883 (4%)
Query: 38 MKRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLC 97
MKRAAAK LIE+Y++QL +G C N C NE A F +
Sbjct: 1 MKRAAAKHLIERYYHQLTEG-----CGNEACT----------NEFCASC-PTFLRMDNNA 44
Query: 98 SSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQNITTPEPSTASRGEPHTSHTAX 157
+++ ++ + ++ +P PS G + +K N + E +G
Sbjct: 45 AAIKALELYKINAKLCDPHPSKK-GASSAYLENSKGAPNNSCSEIKMNKKGA--RIDFKD 101
Query: 158 XXXXXXXXXYNSKDYQNVVLDGAPLTEE--RIYKLCDECLQN--RAEEPLSKALSKAFSR 213
Y + D +PL R++ + +Q+ + ++ + L ++
Sbjct: 102 VTYLTEEKVYEILELCREREDYSPLIRVIGRVFSSAEALVQSFRKVKQHTKEELKSLQAK 161
Query: 214 PSILARCFASKISENANXXXXXXXXXXXXXXRSCDPDKDIDSVAAPQL--DVASCRRAFQ 271
K + +A S D ++ + + D+ + RR +
Sbjct: 162 DEDKDEDEKEKAARSAAAMEEDSEASSSRIGDSSQGDNNLQKLGPDDVSVDIDAIRRVYT 221
Query: 272 YLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITFELPNLGCSDYF 329
L E T + AL L + DL + D +N F+I E NL +Y
Sbjct: 222 RLPS--NEKIETAFLNALVYLSPNVECDLTYHSVYSRDPNYLNLFIIVMENRNLHSPEYL 279
Query: 330 EIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRVVSCNYHVFFHV 389
E+ALP C A +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V+S ++ V
Sbjct: 280 EMALPLFCKATSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKVISNEFNSRNLV 339
Query: 390 QEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIVIAHQHDPLESVLGHLYPPSS 446
+D + ++ LK++YYA+++ G +D+N E EPI + + L+ +LG +
Sbjct: 340 NDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELT-LQELLGE--ERRN 396
Query: 447 MKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDCEDYEMVISRPN 506
KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDKD Y
Sbjct: 397 KKGPRV----DPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKD---YTFFKVETE 449
Query: 507 TRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEPFLRLRVRRSHL 566
+FSF+ PF+L +K+LGLYY+NR+RMYSE R + P+LRL+VRR H+
Sbjct: 450 NKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNPYLRLKVRRDHI 509
Query: 567 IEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMFTH 626
I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEEIFNPD GMFT+
Sbjct: 510 IDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTY 569
Query: 627 QQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLV 686
+ ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL+G+KG+F DL
Sbjct: 570 DESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTFRDLG 629
Query: 687 DWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKK 746
D +P+LY LKD+LEY G ++E+ TF+I D+FG M ++LK NGD I +T EN+K
Sbjct: 630 DSHPVLYQSLKDLLEYEG-NVEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNENRK 688
Query: 747 EFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELE 806
EFV+LY+D++LN SVE QF+AFRRGF MVT+E PL FRPEE+E+L+CGS+ DF LE
Sbjct: 689 EFVNLYSDYILNKSVEKQFKAFRRGFHMVTNEPPLKYLFRPEEIELLICGSRNLDFQALE 748
Query: 807 KSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVIARNG 866
++TEYDGGY DS ++++FW IVHS E KR LQFTTG+DR PVGGL L +IA+NG
Sbjct: 749 ETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMIIAKNG 808
Query: 867 PDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
PD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 809 PDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 851
>U84404-1|AAB49301.1| 852|Homo sapiens E6-associated protein
E6-AP/ubiquitin-protein ligase protein.
Length = 852
Score = 691 bits (1707), Expect = 0.0
Identities = 346/654 (52%), Positives = 456/654 (69%), Gaps = 18/654 (2%)
Query: 261 LDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITF 318
+D+ + RR + L + E T + AL L + DL + D +N F+I
Sbjct: 211 VDIDAIRRVYTRL--LSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIVM 268
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V
Sbjct: 269 ENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKV 328
Query: 379 VSCNYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIVIAHQHDPLE 435
+S ++ V +D + ++ LK++YYA+++ G +D+N E EPI + + L+
Sbjct: 329 ISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELT-LQ 387
Query: 436 SVLGHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC 495
+LG + KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDKD
Sbjct: 388 ELLGE--ERRNKKGPRV----DPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKD- 440
Query: 496 EDYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEP 555
Y +FSF+ PF+L +K+LGLYY+NR+RMYSE R + P
Sbjct: 441 --YTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNP 498
Query: 556 FLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEE 615
+LRL+VRR H+I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEE
Sbjct: 499 YLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEE 558
Query: 616 IFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKL 675
IFNPD GMFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL
Sbjct: 559 IFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKL 618
Query: 676 LGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNG 735
+G+KG+F DL D +P+LY LKD+LEY G ++E+ TF+I D+FG M ++LK NG
Sbjct: 619 MGKKGTFRDLGDSHPVLYQSLKDLLEYEG-NVEDDMMITFQISQTDLFGNPMMYDLKENG 677
Query: 736 DNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVC 795
D I +T EN+KEFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FRPEE+E+L+C
Sbjct: 678 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 737
Query: 796 GSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGL 855
GS+ DF LE++TEYDGGY DS ++++FW IVHS E KR LQFTTG+DR PVGGL
Sbjct: 738 GSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 797
Query: 856 CNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
L +IA+NGPD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 798 GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 851
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/98 (40%), Positives = 59/98 (60%), Gaps = 6/98 (6%)
Query: 38 MKRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLC 97
MKRAAAK LIE+Y++QL +GCGN C N +CAS + N AA +A++L+ A+LC
Sbjct: 1 MKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLC 60
Query: 98 SSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQ 135
P+ + S++Y +S PN+ + SE K N+
Sbjct: 61 D---PHPSKKGASSAY--LENSKGAPNN-SCSEIKMNK 92
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 132 KENQNITTPEPSTASRGEPHTSHTAXXXXXX-XXXXYNSKDYQNVVLDGAPLTEERIYKL 190
K N + P PS + ++ N K + D LTEE++Y++
Sbjct: 54 KINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEI 113
Query: 191 CDECLQNRAEEPLSKALSKAFSRPSILARCF 221
+ C + PL + + + FS L + F
Sbjct: 114 LELCREREDYSPLIRVIGRVFSSAEALVQSF 144
>AF273050-1|AAG34910.1| 852|Homo sapiens CTCL tumor antigen se37-2
protein.
Length = 852
Score = 691 bits (1707), Expect = 0.0
Identities = 346/654 (52%), Positives = 456/654 (69%), Gaps = 18/654 (2%)
Query: 261 LDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITF 318
+D+ + RR + L + E T + AL L + DL + D +N F+I
Sbjct: 211 VDIDAIRRVYTRL--LSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIVM 268
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V
Sbjct: 269 ENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKV 328
Query: 379 VSCNYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIVIAHQHDPLE 435
+S ++ V +D + ++ LK++YYA+++ G +D+N E EPI + + L+
Sbjct: 329 ISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELT-LQ 387
Query: 436 SVLGHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC 495
+LG + KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDKD
Sbjct: 388 ELLGE--ERRNKKGPRV----DPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKD- 440
Query: 496 EDYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEP 555
Y +FSF+ PF+L +K+LGLYY+NR+RMYSE R + P
Sbjct: 441 --YTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNP 498
Query: 556 FLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEE 615
+LRL+VRR H+I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEE
Sbjct: 499 YLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEE 558
Query: 616 IFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKL 675
IFNPD GMFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL
Sbjct: 559 IFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKL 618
Query: 676 LGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNG 735
+G+KG+F DL D +P+LY LKD+LEY G ++E+ TF+I D+FG M ++LK NG
Sbjct: 619 MGKKGTFRDLGDSHPVLYQSLKDLLEYEG-NVEDDMMITFQISQTDLFGNPMMYDLKENG 677
Query: 736 DNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVC 795
D I +T EN+KEFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FRPEE+E+L+C
Sbjct: 678 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 737
Query: 796 GSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGL 855
GS+ DF LE++TEYDGGY DS ++++FW IVHS E KR LQFTTG+DR PVGGL
Sbjct: 738 GSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 797
Query: 856 CNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
L +IA+NGPD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 798 GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 851
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/98 (40%), Positives = 59/98 (60%), Gaps = 6/98 (6%)
Query: 38 MKRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLC 97
MKRAAAK LIE+Y++QL +GCGN C N +CAS + N AA +A++L+ A+LC
Sbjct: 1 MKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLC 60
Query: 98 SSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQ 135
P+ + S++Y +S PN+ + SE K N+
Sbjct: 61 D---PHPSKKGASSAY--LENSKGAPNN-SCSEIKMNK 92
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 132 KENQNITTPEPSTASRGEPHTSHTAXXXXXX-XXXXYNSKDYQNVVLDGAPLTEERIYKL 190
K N + P PS + ++ N K + D LTEE++Y++
Sbjct: 54 KINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEI 113
Query: 191 CDECLQNRAEEPLSKALSKAFSRPSILARCF 221
+ C + PL + + + FS L + F
Sbjct: 114 LELCREREDYSPLIRVIGRVFSSAEALVQSF 144
>AF016708-1|AAB69154.1| 852|Homo sapiens E6-AP ubiquitin-protein
ligase protein.
Length = 852
Score = 691 bits (1707), Expect = 0.0
Identities = 346/654 (52%), Positives = 456/654 (69%), Gaps = 18/654 (2%)
Query: 261 LDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITF 318
+D+ + RR + L + E T + AL L + DL + D +N F+I
Sbjct: 211 VDIDAIRRVYTRL--LSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIVM 268
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V
Sbjct: 269 ENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKV 328
Query: 379 VSCNYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIVIAHQHDPLE 435
+S ++ V +D + ++ LK++YYA+++ G +D+N E EPI + + L+
Sbjct: 329 ISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELT-LQ 387
Query: 436 SVLGHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC 495
+LG + KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDKD
Sbjct: 388 ELLGE--ERRNKKGPRV----DPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKD- 440
Query: 496 EDYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEP 555
Y +FSF+ PF+L +K+LGLYY+NR+RMYSE R + P
Sbjct: 441 --YTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNP 498
Query: 556 FLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEE 615
+LRL+VRR H+I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEE
Sbjct: 499 YLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEE 558
Query: 616 IFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKL 675
IFNPD GMFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL
Sbjct: 559 IFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKL 618
Query: 676 LGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNG 735
+G+KG+F DL D +P+LY LKD+LEY G ++E+ TF+I D+FG M ++LK NG
Sbjct: 619 MGKKGTFRDLGDSHPVLYQSLKDLLEYEG-NVEDDMMITFQISQTDLFGNPMMYDLKENG 677
Query: 736 DNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVC 795
D I +T EN+KEFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FRPEE+E+L+C
Sbjct: 678 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 737
Query: 796 GSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGL 855
GS+ DF LE++TEYDGGY DS ++++FW IVHS E KR LQFTTG+DR PVGGL
Sbjct: 738 GSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 797
Query: 856 CNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
L +IA+NGPD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 798 GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 851
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/98 (40%), Positives = 59/98 (60%), Gaps = 6/98 (6%)
Query: 38 MKRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLC 97
MKRAAAK LIE+Y++QL +GCGN C N +CAS + N AA +A++L+ A+LC
Sbjct: 1 MKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLC 60
Query: 98 SSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQ 135
P+ + S++Y +S PN+ + SE K N+
Sbjct: 61 D---PHPSKKGASSAY--LENSKGAPNN-SCSEIKMNK 92
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 132 KENQNITTPEPSTASRGEPHTSHTAXXXXXX-XXXXYNSKDYQNVVLDGAPLTEERIYKL 190
K N + P PS + ++ N K + D LTEE++Y++
Sbjct: 54 KINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEI 113
Query: 191 CDECLQNRAEEPLSKALSKAFSRPSILARCF 221
+ C + PL + + + FS L + F
Sbjct: 114 LELCREREDYSPLIRVIGRVFSSAEALVQSF 144
>X98033-1|CAA66656.1| 852|Homo sapiens E6-AP protein.
Length = 852
Score = 690 bits (1705), Expect = 0.0
Identities = 346/654 (52%), Positives = 456/654 (69%), Gaps = 18/654 (2%)
Query: 261 LDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITF 318
+D+ + RR + L + E T + AL L + DL + D +N F+I
Sbjct: 211 VDIDAIRRVYTRL--LSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIGM 268
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V
Sbjct: 269 ENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKV 328
Query: 379 VSCNYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIVIAHQHDPLE 435
+S ++ V +D + ++ LK++YYA+++ G +D+N E EPI + + L+
Sbjct: 329 ISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELT-LQ 387
Query: 436 SVLGHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC 495
+LG + KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDKD
Sbjct: 388 ELLGE--ERRNKKGPRV----DPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKD- 440
Query: 496 EDYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEP 555
Y +FSF+ PF+L +K+LGLYY+NR+RMYSE R + P
Sbjct: 441 --YTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNP 498
Query: 556 FLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEE 615
+LRL+VRR H+I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEE
Sbjct: 499 YLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEE 558
Query: 616 IFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKL 675
IFNPD GMFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL
Sbjct: 559 IFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKL 618
Query: 676 LGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNG 735
+G+KG+F DL D +P+LY LKD+LEY G ++E+ TF+I D+FG M ++LK NG
Sbjct: 619 MGKKGTFRDLGDSHPVLYQSLKDLLEYEG-NVEDDMMITFQISQTDLFGNPMMYDLKENG 677
Query: 736 DNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVC 795
D I +T EN+KEFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FRPEE+E+L+C
Sbjct: 678 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 737
Query: 796 GSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGL 855
GS+ DF LE++TEYDGGY DS ++++FW IVHS E KR LQFTTG+DR PVGGL
Sbjct: 738 GSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 797
Query: 856 CNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
L +IA+NGPD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 798 GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 851
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/98 (40%), Positives = 59/98 (60%), Gaps = 6/98 (6%)
Query: 38 MKRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLC 97
MKRAAAK LIE+Y++QL +GCGN C N +CAS + N AA +A++L+ A+LC
Sbjct: 1 MKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLC 60
Query: 98 SSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQ 135
P+ + S++Y +S PN+ + SE K N+
Sbjct: 61 D---PHPSKKGASSAY--LENSKGAPNN-SCSEIKMNK 92
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 132 KENQNITTPEPSTASRGEPHTSHTAXXXXXX-XXXXYNSKDYQNVVLDGAPLTEERIYKL 190
K N + P PS + ++ N K + D LTEE++Y++
Sbjct: 54 KINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEI 113
Query: 191 CDECLQNRAEEPLSKALSKAFSRPSILARCF 221
+ C + PL + + + FS L + F
Sbjct: 114 LELCREREDYSPLIRVIGRVFSSAEALVQSF 144
>X98032-1|CAA66655.1| 852|Homo sapiens E6-AP protein.
Length = 852
Score = 690 bits (1705), Expect = 0.0
Identities = 346/654 (52%), Positives = 456/654 (69%), Gaps = 18/654 (2%)
Query: 261 LDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITF 318
+D+ + RR + L + E T + AL L + DL + D +N F+I
Sbjct: 211 VDIDAIRRVYTRL--LSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIGM 268
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V
Sbjct: 269 ENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKV 328
Query: 379 VSCNYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIVIAHQHDPLE 435
+S ++ V +D + ++ LK++YYA+++ G +D+N E EPI + + L+
Sbjct: 329 ISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELT-LQ 387
Query: 436 SVLGHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC 495
+LG + KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDKD
Sbjct: 388 ELLGE--ERRNKKGPRV----DPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKD- 440
Query: 496 EDYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEP 555
Y +FSF+ PF+L +K+LGLYY+NR+RMYSE R + P
Sbjct: 441 --YTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNP 498
Query: 556 FLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEE 615
+LRL+VRR H+I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEE
Sbjct: 499 YLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEE 558
Query: 616 IFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKL 675
IFNPD GMFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL
Sbjct: 559 IFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKL 618
Query: 676 LGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNG 735
+G+KG+F DL D +P+LY LKD+LEY G ++E+ TF+I D+FG M ++LK NG
Sbjct: 619 MGKKGTFRDLGDSHPVLYQSLKDLLEYEG-NVEDDMMITFQISQTDLFGNPMMYDLKENG 677
Query: 736 DNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVC 795
D I +T EN+KEFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FRPEE+E+L+C
Sbjct: 678 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 737
Query: 796 GSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGL 855
GS+ DF LE++TEYDGGY DS ++++FW IVHS E KR LQFTTG+DR PVGGL
Sbjct: 738 GSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 797
Query: 856 CNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
L +IA+NGPD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 798 GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 851
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/98 (40%), Positives = 59/98 (60%), Gaps = 6/98 (6%)
Query: 38 MKRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLC 97
MKRAAAK LIE+Y++QL +GCGN C N +CAS + N AA +A++L+ A+LC
Sbjct: 1 MKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLC 60
Query: 98 SSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQ 135
P+ + S++Y +S PN+ + SE K N+
Sbjct: 61 D---PHPSKKGASSAY--LENSKGAPNN-SCSEIKMNK 92
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 132 KENQNITTPEPSTASRGEPHTSHTAXXXXXX-XXXXYNSKDYQNVVLDGAPLTEERIYKL 190
K N + P PS + ++ N K + D LTEE++Y++
Sbjct: 54 KINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEI 113
Query: 191 CDECLQNRAEEPLSKALSKAFSRPSILARCF 221
+ C + PL + + + FS L + F
Sbjct: 114 LELCREREDYSPLIRVIGRVFSSAEALVQSF 144
>X98031-1|CAA66654.1| 852|Homo sapiens E6-AP protein.
Length = 852
Score = 690 bits (1705), Expect = 0.0
Identities = 346/654 (52%), Positives = 456/654 (69%), Gaps = 18/654 (2%)
Query: 261 LDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITF 318
+D+ + RR + L + E T + AL L + DL + D +N F+I
Sbjct: 211 VDIDAIRRVYTRL--LSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIGM 268
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V
Sbjct: 269 ENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKV 328
Query: 379 VSCNYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIVIAHQHDPLE 435
+S ++ V +D + ++ LK++YYA+++ G +D+N E EPI + + L+
Sbjct: 329 ISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELT-LQ 387
Query: 436 SVLGHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC 495
+LG + KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDKD
Sbjct: 388 ELLGE--ERRNKKGPRV----DPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKD- 440
Query: 496 EDYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEP 555
Y +FSF+ PF+L +K+LGLYY+NR+RMYSE R + P
Sbjct: 441 --YTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNP 498
Query: 556 FLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEE 615
+LRL+VRR H+I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEE
Sbjct: 499 YLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEE 558
Query: 616 IFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKL 675
IFNPD GMFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL
Sbjct: 559 IFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKL 618
Query: 676 LGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNG 735
+G+KG+F DL D +P+LY LKD+LEY G ++E+ TF+I D+FG M ++LK NG
Sbjct: 619 MGKKGTFRDLGDSHPVLYQSLKDLLEYEG-NVEDDMMITFQISQTDLFGNPMMYDLKENG 677
Query: 736 DNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVC 795
D I +T EN+KEFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FRPEE+E+L+C
Sbjct: 678 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 737
Query: 796 GSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGL 855
GS+ DF LE++TEYDGGY DS ++++FW IVHS E KR LQFTTG+DR PVGGL
Sbjct: 738 GSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 797
Query: 856 CNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
L +IA+NGPD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 798 GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 851
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/98 (40%), Positives = 59/98 (60%), Gaps = 6/98 (6%)
Query: 38 MKRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLC 97
MKRAAAK LIE+Y++QL +GCGN C N +CAS + N AA +A++L+ A+LC
Sbjct: 1 MKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLC 60
Query: 98 SSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQ 135
P+ + S++Y +S PN+ + SE K N+
Sbjct: 61 D---PHPSKKGASSAY--LENSKGAPNN-SCSEIKMNK 92
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 132 KENQNITTPEPSTASRGEPHTSHTAXXXXXX-XXXXYNSKDYQNVVLDGAPLTEERIYKL 190
K N + P PS + ++ N K + D LTEE++Y++
Sbjct: 54 KINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEI 113
Query: 191 CDECLQNRAEEPLSKALSKAFSRPSILARCF 221
+ C + PL + + + FS L + F
Sbjct: 114 LELCREREDYSPLIRVIGRVFSSAEALVQSF 144
>X98021-1|CAA66653.1| 852|Homo sapiens E6-AP protein.
Length = 852
Score = 690 bits (1705), Expect = 0.0
Identities = 346/654 (52%), Positives = 456/654 (69%), Gaps = 18/654 (2%)
Query: 261 LDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITF 318
+D+ + RR + L + E T + AL L + DL + D +N F+I
Sbjct: 211 VDIDAIRRVYTRL--LSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIGM 268
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V
Sbjct: 269 ENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKV 328
Query: 379 VSCNYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIVIAHQHDPLE 435
+S ++ V +D + ++ LK++YYA+++ G +D+N E EPI + + L+
Sbjct: 329 ISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELT-LQ 387
Query: 436 SVLGHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC 495
+LG + KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDKD
Sbjct: 388 ELLGE--ERRNKKGPRV----DPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKD- 440
Query: 496 EDYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEP 555
Y +FSF+ PF+L +K+LGLYY+NR+RMYSE R + P
Sbjct: 441 --YTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNP 498
Query: 556 FLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEE 615
+LRL+VRR H+I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEE
Sbjct: 499 YLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEE 558
Query: 616 IFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKL 675
IFNPD GMFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL
Sbjct: 559 IFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKL 618
Query: 676 LGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNG 735
+G+KG+F DL D +P+LY LKD+LEY G ++E+ TF+I D+FG M ++LK NG
Sbjct: 619 MGKKGTFRDLGDSHPVLYQSLKDLLEYEG-NVEDDMMITFQISQTDLFGNPMMYDLKENG 677
Query: 736 DNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVC 795
D I +T EN+KEFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FRPEE+E+L+C
Sbjct: 678 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 737
Query: 796 GSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGL 855
GS+ DF LE++TEYDGGY DS ++++FW IVHS E KR LQFTTG+DR PVGGL
Sbjct: 738 GSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 797
Query: 856 CNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
L +IA+NGPD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 798 GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 851
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/98 (40%), Positives = 59/98 (60%), Gaps = 6/98 (6%)
Query: 38 MKRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLC 97
MKRAAAK LIE+Y++QL +GCGN C N +CAS + N AA +A++L+ A+LC
Sbjct: 1 MKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLC 60
Query: 98 SSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQ 135
P+ + S++Y +S PN+ + SE K N+
Sbjct: 61 D---PHPSKKGASSAY--LENSKGAPNN-SCSEIKMNK 92
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 132 KENQNITTPEPSTASRGEPHTSHTAXXXXXX-XXXXYNSKDYQNVVLDGAPLTEERIYKL 190
K N + P PS + ++ N K + D LTEE++Y++
Sbjct: 54 KINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEI 113
Query: 191 CDECLQNRAEEPLSKALSKAFSRPSILARCF 221
+ C + PL + + + FS L + F
Sbjct: 114 LELCREREDYSPLIRVIGRVFSSAEALVQSF 144
>BC002582-1|AAH02582.2| 872|Homo sapiens ubiquitin protein ligase
E3A (human papilloma virus E6-associated protein, Ange
protein.
Length = 872
Score = 688 bits (1700), Expect = 0.0
Identities = 345/654 (52%), Positives = 455/654 (69%), Gaps = 18/654 (2%)
Query: 261 LDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITF 318
+D+ + RR + L + E T + AL L + DL + D +N F+I
Sbjct: 231 VDIDAIRRVYTRL--LSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIVM 288
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V
Sbjct: 289 ENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKV 348
Query: 379 VSCNYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIVIAHQHDPLE 435
+S ++ V +D + ++ LK++YYA+++ G +D+N E EPI + + L+
Sbjct: 349 ISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELT-LQ 407
Query: 436 SVLGHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC 495
+LG + KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDKD
Sbjct: 408 ELLGE--ERRNKKGPRV----DPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKD- 460
Query: 496 EDYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEP 555
Y +FSF+ PF+L +K+LGLYY+NR+RMYSE R + P
Sbjct: 461 --YTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNP 518
Query: 556 FLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEE 615
+LRL+VRR H+I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEE
Sbjct: 519 YLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEE 578
Query: 616 IFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKL 675
IFNPD GMFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL
Sbjct: 579 IFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKL 638
Query: 676 LGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNG 735
+G+KG+F DL D +P+LY LKD+LEY G ++E+ TF+I D+FG M ++LK NG
Sbjct: 639 MGKKGTFRDLGDSHPVLYQSLKDLLEYEG-NVEDDMMITFQISQTDLFGNPMMYDLKENG 697
Query: 736 DNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVC 795
D I +T EN+KEFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FRPEE+E+L+C
Sbjct: 698 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 757
Query: 796 GSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGL 855
GS+ F LE++TEYDGGY DS ++++FW IVHS E KR LQFTTG+DR PVGGL
Sbjct: 758 GSRNLGFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 817
Query: 856 CNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
L +IA+NGPD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 818 GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 871
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/98 (40%), Positives = 59/98 (60%), Gaps = 6/98 (6%)
Query: 38 MKRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLC 97
MKRAAAK LIE+Y++QL +GCGN C N +CAS + N AA +A++L+ A+LC
Sbjct: 21 MKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLC 80
Query: 98 SSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQ 135
P+ + S++Y +S PN+ + SE K N+
Sbjct: 81 D---PHPSKKGASSAY--LENSKGAPNN-SCSEIKMNK 112
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 132 KENQNITTPEPSTASRGEPHTSHTAXXXXXX-XXXXYNSKDYQNVVLDGAPLTEERIYKL 190
K N + P PS + ++ N K + D LTEE++Y++
Sbjct: 74 KINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEI 133
Query: 191 CDECLQNRAEEPLSKALSKAFSRPSILARCF 221
+ C + PL + + + FS L + F
Sbjct: 134 LELCREREDYSPLIRVIGRVFSSAEALVQSF 164
>BC009271-1|AAH09271.1| 585|Homo sapiens UBE3A protein protein.
Length = 585
Score = 679 bits (1677), Expect = 0.0
Identities = 330/591 (55%), Positives = 430/591 (72%), Gaps = 14/591 (2%)
Query: 322 NLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRVVSC 381
NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V+S
Sbjct: 5 NLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKVISN 64
Query: 382 NYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIVIAHQHDPLESVL 438
++ V +D + ++ LK++YYA+++ G +D+N E EPI + + L+ +L
Sbjct: 65 EFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELT-LQELL 123
Query: 439 GHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDCEDY 498
G + KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDKD Y
Sbjct: 124 GE--ERRNKKGPRV----DPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKD---Y 174
Query: 499 EMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEPFLR 558
+FSF+ PF+L +K+LGLYY+NR+RMYSE R + P+LR
Sbjct: 175 TFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNPYLR 234
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
L+VRR H+I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEEIFN
Sbjct: 235 LKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFN 294
Query: 619 PDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGR 678
PD GMFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL+G+
Sbjct: 295 PDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGK 354
Query: 679 KGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNI 738
KG+F DL D +P+LY LKD+LEY G ++E+ TF+I D+FG M ++LK NGD I
Sbjct: 355 KGTFRDLGDSHPVLYQSLKDLLEYEG-NVEDDMMITFQISQTDLFGNPMMYDLKENGDKI 413
Query: 739 FVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSK 798
+T EN+KEFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FRPEE+E+L+CGS+
Sbjct: 414 PITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSR 473
Query: 799 VFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNL 858
DF LE++TEYDGGY DS ++++FW IVHS E KR LQFTTG+DR PVGGL L
Sbjct: 474 NLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKL 533
Query: 859 NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
+IA+NGPD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 534 KMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 584
>L07557-1|AAA35542.1| 874|Homo sapiens oncogenic protein-associated
protein protein.
Length = 874
Score = 677 bits (1673), Expect = 0.0
Identities = 346/663 (52%), Positives = 457/663 (68%), Gaps = 27/663 (4%)
Query: 261 LDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITF 318
+D+ + RR + L + E T + AL L + DL + D +N F+I
Sbjct: 224 VDIDAIRRVYTRL--LSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIGM 281
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V
Sbjct: 282 ENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKV 341
Query: 379 VSCNYHVF-----FH----VQEDGHVTGPTRVLKVLYYASILAGVLDSNTLHE---EPIV 426
+S ++ F+ V +D + ++ LK++YYA+++ G +D+N E EPI
Sbjct: 342 ISNEFNSRNLVNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIP 401
Query: 427 IAHQHDPLESVLGHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLS 486
+ + L+ +LG + KG R DPL ELGV LD R P +PFE+F NEPL+
Sbjct: 402 ESSELT-LQELLGE--ERRNKKGLRV----DPLETELGVKTLDCRKPLIPFEEFINEPLN 454
Query: 487 DVIEMDKDCEDYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXX 546
+V+EMDKD Y +FSF+ PF+L +K+LGLYY+NR+RMYSE R
Sbjct: 455 EVLEMDKD---YTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYS 511
Query: 547 XXXXXRPEPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSK 606
+ P+LRL+VRR H+I+DALV LEMI+ME DLKKQL VEFEGEQGVDEGGVSK
Sbjct: 512 LVQGQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSK 571
Query: 607 EFFQLIVEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVN 666
EFFQL+VEEIFNPD GMFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+
Sbjct: 572 EFFQLVVEEIFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVH 631
Query: 667 FPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTN 726
FPMVVYRKL+G+KG F DL D +P+LY LKD+LEY G ++E+ TF+I ++FG
Sbjct: 632 FPMVVYRKLMGKKGLFVDLGDSHPVLYQSLKDLLEYVG-NVEDDMMITFQISQTNLFGNP 690
Query: 727 MFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFR 786
M ++LK NGD I +T EN+KEFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FR
Sbjct: 691 MMYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFR 750
Query: 787 PEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTG 846
PEE+E+L+CGS+ DF LE++TEYDGGY DS ++++FW IVHS E KR LQFTTG
Sbjct: 751 PEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTG 810
Query: 847 SDRVPVGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKG 906
+DR PVGGL L +IA+NGPD +RLPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KG
Sbjct: 811 TDRAPVGGLGKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKG 870
Query: 907 FGL 909
FG+
Sbjct: 871 FGM 873
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/98 (40%), Positives = 59/98 (60%), Gaps = 6/98 (6%)
Query: 38 MKRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLC 97
MKRAAAK LIE+Y++QL +GCGN C N +CAS + N AA +A++L+ A+LC
Sbjct: 14 MKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLC 73
Query: 98 SSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQ 135
P+ + S++Y +S PN+ + SE K N+
Sbjct: 74 D---PHPSKKGASSAY--LENSKGAPNN-SCSEIKMNK 105
Score = 33.1 bits (72), Expect = 4.6
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 132 KENQNITTPEPSTASRGEPHTSHTAXXXXXX-XXXXYNSKDYQNVVLDGAPLTEERIYKL 190
K N + P PS + ++ N K + D LTEE++Y++
Sbjct: 67 KINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEI 126
Query: 191 CDECLQNRAEEPLSKALSKAFSRPSILARCF 221
+ C + PL + + + FS L + F
Sbjct: 127 LELCREREDYSPLIRVIGRVFSSAEALVQSF 157
>AL161798-4|CAH70053.1| 776|Homo sapiens HECT domain containing 2
protein.
Length = 776
Score = 350 bits (861), Expect = 1e-95
Identities = 191/455 (41%), Positives = 283/455 (62%), Gaps = 30/455 (6%)
Query: 473 PYLPFEDFYNEPLSDVIEMDKDCEDYEMVISRPNT-RFSFLRHPFVLTVASKSLGLYYEN 531
P +P+ DFYN L + M E+Y + N+ RFSF ++PFV++VA+K + + ++
Sbjct: 333 PLIPYTDFYNSTLDHIDLM----EEYHTWQNFGNSHRFSFCQYPFVISVAAKKIIIQRDS 388
Query: 532 RLRMYSESRXXXXXXXXXXXRPEP---FLRLRVRRSHLIEDALVVLEMISMERALDLKKQ 588
+M + +R RP+ FL ++VRR+HL+ D+L + ++ +RA DLKK+
Sbjct: 389 EQQMINIARQSLVDKVSRRQRPDMNILFLNMKVRRTHLVSDSL---DELTRKRA-DLKKK 444
Query: 589 LVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTL 648
L V F GE G+D GG++KE+F L++ +IF+PDYGMFT+ +DS WF+ + ++F L
Sbjct: 445 LKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKCDNYSEFRL 504
Query: 649 IGIVLGLAIYNNVILAVNFPMVVYRKLLGR--------------KGSFEDLVDWNPILYN 694
+GI++GLA+YN++ L + FP Y+KLL + +DL P L +
Sbjct: 505 VGILMGLAVYNSITLDIRFPPCCYKKLLSPPIIPSDQNIPVGICNVTVDDLCQIMPELAH 564
Query: 695 GLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDLYAD 754
GL ++L + G+ +EE +Y TF++ +Q+ FG + LK GD I VT +N+KE+V LY D
Sbjct: 565 GLSELLSHEGN-VEEDFYSTFQV-FQEEFGIIKSYNLKPGGDKISVTNQNRKEYVQLYTD 622
Query: 755 FLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGG 814
FLLN S+ QF AF GF V + L RPEEVE+LVCGS D H L++ST+YDG
Sbjct: 623 FLLNKSIYKQFAAFYYGFHSVCASNAL-MLLRPEEVEILVCGSPDLDMHALQRSTQYDG- 680
Query: 815 YASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVIARNGPDCDRLPT 874
YA ++ FW +V PL+ ++KLL FTTGSDRVPVGG+ +LNF I++N + LP
Sbjct: 681 YAKTDLTIKYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNCLPV 740
Query: 875 AHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
AHTCFN L LP Y ++ L+ +L+ I+ S+GFGL
Sbjct: 741 AHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGL 775
>BC040187-1|AAH40187.1| 776|Homo sapiens HECT domain containing 2
protein.
Length = 776
Score = 349 bits (857), Expect = 3e-95
Identities = 190/455 (41%), Positives = 282/455 (61%), Gaps = 30/455 (6%)
Query: 473 PYLPFEDFYNEPLSDVIEMDKDCEDYEMVISRPNT-RFSFLRHPFVLTVASKSLGLYYEN 531
P +P+ DFYN L + M E+Y + N+ RFSF ++PFV++VA+K + + ++
Sbjct: 333 PLIPYTDFYNSTLDHIDLM----EEYHTWQNFGNSHRFSFCQYPFVISVAAKKIIIQRDS 388
Query: 532 RLRMYSESRXXXXXXXXXXXRPEP---FLRLRVRRSHLIEDALVVLEMISMERALDLKKQ 588
+M + +R RP+ FL ++VRR+HL+ D+L + ++ +RA DLKK+
Sbjct: 389 EQQMINIARQSLVDKVSRRQRPDMNILFLNMKVRRTHLVSDSL---DELTRKRA-DLKKK 444
Query: 589 LVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTL 648
L V F GE G+D GG++KE+F L++ +IF+PDYGMFT+ +DS WF+ + ++F L
Sbjct: 445 LKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKCDNYSEFRL 504
Query: 649 IGIVLGLAIYNNVILAVNFPMVVYRKLLGR--------------KGSFEDLVDWNPILYN 694
+GI++GLA+YN++ + FP Y+KLL + +DL P L +
Sbjct: 505 VGILMGLAVYNSITFDIRFPPCCYKKLLSPPIIPSGQNIPVGICNVTVDDLCQIMPELAH 564
Query: 695 GLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDLYAD 754
GL ++L + G+ +EE +Y TF++ +Q+ FG + LK GD I VT +N+KE+V LY D
Sbjct: 565 GLSELLSHEGN-VEEDFYSTFQV-FQEEFGIIKSYNLKPGGDKISVTNQNRKEYVQLYTD 622
Query: 755 FLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGG 814
FLLN S+ QF AF GF V + L RPEEVE+LVCGS D H L++ST+YDG
Sbjct: 623 FLLNKSIYKQFAAFYYGFHSVCASNAL-MLLRPEEVEILVCGSPDLDMHALQRSTQYDG- 680
Query: 815 YASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVIARNGPDCDRLPT 874
YA ++ FW +V PL+ ++KLL FTTGSDRVPVGG+ +LNF I++N + LP
Sbjct: 681 YAKTDLTIKYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNCLPV 740
Query: 875 AHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
AHTCFN L LP Y ++ L+ +L+ I+ S+GFGL
Sbjct: 741 AHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGL 775
>AL161798-1|CAH70050.1| 426|Homo sapiens HECT domain containing 2
protein.
Length = 426
Score = 339 bits (833), Expect = 3e-92
Identities = 180/419 (42%), Positives = 266/419 (63%), Gaps = 25/419 (5%)
Query: 508 RFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEP---FLRLRVRRS 564
RFSF ++PFV++VA+K + + ++ +M + +R RP+ FL ++VRR+
Sbjct: 15 RFSFCQYPFVISVAAKKIIIQRDSEQQMINIARQSLVDKVSRRQRPDMNILFLNMKVRRT 74
Query: 565 HLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMF 624
HL+ D+L + ++ +RA DLKK+L V F GE G+D GG++KE+F L++ +IF+PDYGMF
Sbjct: 75 HLVSDSL---DELTRKRA-DLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMF 130
Query: 625 THQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGR------ 678
T+ +DS WF+ + ++F L+GI++GLA+YN++ L + FP Y+KLL
Sbjct: 131 TYHKDSHCHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPIIPSD 190
Query: 679 --------KGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHE 730
+ +DL P L +GL ++L + G+ +EE +Y TF++ +Q+ FG +
Sbjct: 191 QNIPVGICNVTVDDLCQIMPELAHGLSELLSHEGN-VEEDFYSTFQV-FQEEFGIIKSYN 248
Query: 731 LKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEV 790
LK GD I VT +N+KE+V LY DFLLN S+ QF AF GF V + L RPEEV
Sbjct: 249 LKPGGDKISVTNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNAL-MLLRPEEV 307
Query: 791 EMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRV 850
E+LVCGS D H L++ST+YDG YA ++ FW +V PL+ ++KLL FTTGSDRV
Sbjct: 308 EILVCGSPDLDMHALQRSTQYDG-YAKTDLTIKYFWDVVLGFPLDLQKKLLHFTTGSDRV 366
Query: 851 PVGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
PVGG+ +LNF I++N + LP AHTCFN L LP Y ++ L+ +L+ I+ S+GFGL
Sbjct: 367 PVGGMADLNFKISKNETSTNCLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGL 425
>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 306 bits (751), Expect = 2e-82
Identities = 174/478 (36%), Positives = 271/478 (56%), Gaps = 20/478 (4%)
Query: 444 PSSMKGARNSQLNDPLAV-ELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC------E 496
P S + NS L+ L V E+ V + + ++ FY + ++I++ D +
Sbjct: 579 PPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQ 638
Query: 497 DYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRP--- 553
Y M+ P T +PFV +K+ L + L+M P
Sbjct: 639 AYGMLADIPVT---ICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIE 695
Query: 554 --EPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQL 611
P L L VRR +++ DA+ E++ + +D KK L V F GE VD GGV KEFF L
Sbjct: 696 SVNPCLILVVRRENIVGDAM---EVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLL 752
Query: 612 IVEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVV 671
I+ E+ +P YGMF + +DSR +WF+ +FE F LIG++ GLAIYN I+ ++FP+ +
Sbjct: 753 IMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLAL 812
Query: 672 YRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHEL 731
Y+KLL +K S +DL + P + ++ +L+Y DD+EE + F I ++ FG EL
Sbjct: 813 YKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVEN-FGATEVKEL 871
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
+NG + V ++N++EFVD Y D++ N SV + F AF GF V L F+P E++
Sbjct: 872 VLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVL-LLFQPNELQ 930
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+V G+ +D+ ELEK+TEY G Y ++ ++ FW + H LPLE K++ L F TGSDR+P
Sbjct: 931 AMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIP 990
Query: 852 VGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
+ G+ +L VI G + LP +HTCFN+L LP+Y ++ L+ +L++AI++++GF L
Sbjct: 991 ILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSL 1048
>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 306 bits (751), Expect = 2e-82
Identities = 174/478 (36%), Positives = 271/478 (56%), Gaps = 20/478 (4%)
Query: 444 PSSMKGARNSQLNDPLAV-ELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC------E 496
P S + NS L+ L V E+ V + + ++ FY + ++I++ D +
Sbjct: 579 PPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQ 638
Query: 497 DYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRP--- 553
Y M+ P T +PFV +K+ L + L+M P
Sbjct: 639 AYGMLADIPVT---ICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIE 695
Query: 554 --EPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQL 611
P L L VRR +++ DA+ E++ + +D KK L V F GE VD GGV KEFF L
Sbjct: 696 SVNPCLILVVRRENIVGDAM---EVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLL 752
Query: 612 IVEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVV 671
I+ E+ +P YGMF + +DSR +WF+ +FE F LIG++ GLAIYN I+ ++FP+ +
Sbjct: 753 IMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLAL 812
Query: 672 YRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHEL 731
Y+KLL +K S +DL + P + ++ +L+Y DD+EE + F I ++ FG EL
Sbjct: 813 YKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVEN-FGATEVKEL 871
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
+NG + V ++N++EFVD Y D++ N SV + F AF GF V L F+P E++
Sbjct: 872 VLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVL-LLFQPNELQ 930
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+V G+ +D+ ELEK+TEY G Y ++ ++ FW + H LPLE K++ L F TGSDR+P
Sbjct: 931 AMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIP 990
Query: 852 VGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
+ G+ +L VI G + LP +HTCFN+L LP+Y ++ L+ +L++AI++++GF L
Sbjct: 991 ILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSL 1048
>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 306 bits (751), Expect = 2e-82
Identities = 174/478 (36%), Positives = 271/478 (56%), Gaps = 20/478 (4%)
Query: 444 PSSMKGARNSQLNDPLAV-ELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC------E 496
P S + NS L+ L V E+ V + + ++ FY + ++I++ D +
Sbjct: 579 PPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQ 638
Query: 497 DYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRP--- 553
Y M+ P T +PFV +K+ L + L+M P
Sbjct: 639 AYGMLADIPVT---ICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIE 695
Query: 554 --EPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQL 611
P L L VRR +++ DA+ E++ + +D KK L V F GE VD GGV KEFF L
Sbjct: 696 SVNPCLILVVRRENIVGDAM---EVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLL 752
Query: 612 IVEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVV 671
I+ E+ +P YGMF + +DSR +WF+ +FE F LIG++ GLAIYN I+ ++FP+ +
Sbjct: 753 IMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLAL 812
Query: 672 YRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHEL 731
Y+KLL +K S +DL + P + ++ +L+Y DD+EE + F I ++ FG EL
Sbjct: 813 YKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVEN-FGATEVKEL 871
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
+NG + V ++N++EFVD Y D++ N SV + F AF GF V L F+P E++
Sbjct: 872 VLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVL-LLFQPNELQ 930
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+V G+ +D+ ELEK+TEY G Y ++ ++ FW + H LPLE K++ L F TGSDR+P
Sbjct: 931 AMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIP 990
Query: 852 VGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
+ G+ +L VI G + LP +HTCFN+L LP+Y ++ L+ +L++AI++++GF L
Sbjct: 991 ILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSL 1048
>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
protein 4 isoform 1 protein.
Length = 1057
Score = 303 bits (743), Expect = 2e-81
Identities = 173/483 (35%), Positives = 273/483 (56%), Gaps = 22/483 (4%)
Query: 444 PSSMKGARNSQLNDPLAV-ELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC------E 496
P S + NS L+ L V E+ V + + ++ FY + ++I++ D +
Sbjct: 579 PPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQ 638
Query: 497 DYEMVISRPNTRFSFL-----RHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXX 551
Y M ++ T + + +PFV +K+ L + L+M
Sbjct: 639 AYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLF 698
Query: 552 RP-----EPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSK 606
P P L L VRR +++ DA+ E++ + +D KK L V F GE VD GGV K
Sbjct: 699 LPVIESVNPCLILVVRRENIVGDAM---EVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRK 755
Query: 607 EFFQLIVEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVN 666
EFF LI+ E+ +P YGMF + +DSR +WF+ +FE F LIG++ GLAIYN I+ ++
Sbjct: 756 EFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLH 815
Query: 667 FPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTN 726
FP+ +Y+KLL +K S +DL + P + ++ +L+Y DD+EE + F I ++ FG
Sbjct: 816 FPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVEN-FGAT 874
Query: 727 MFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFR 786
EL +NG + V ++N++EFVD Y D++ N SV + F AF GF V L F+
Sbjct: 875 EVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVL-LLFQ 933
Query: 787 PEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTG 846
P E++ +V G+ +D+ ELEK+TEY G Y ++ ++ FW + H LPLE K++ L F TG
Sbjct: 934 PNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTG 993
Query: 847 SDRVPVGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKG 906
SDR+P+ G+ +L VI G + LP +HTCFN+L LP+Y ++ L+ +L++AI++++G
Sbjct: 994 SDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEG 1053
Query: 907 FGL 909
F L
Sbjct: 1054 FSL 1056
>AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 303 bits (743), Expect = 2e-81
Identities = 173/483 (35%), Positives = 273/483 (56%), Gaps = 22/483 (4%)
Query: 444 PSSMKGARNSQLNDPLAV-ELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC------E 496
P S + NS L+ L V E+ V + + ++ FY + ++I++ D +
Sbjct: 429 PPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQ 488
Query: 497 DYEMVISRPNTRFSFL-----RHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXX 551
Y M ++ T + + +PFV +K+ L + L+M
Sbjct: 489 AYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLF 548
Query: 552 RP-----EPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSK 606
P P L L VRR +++ DA+ E++ + +D KK L V F GE VD GGV K
Sbjct: 549 LPVIESVNPCLILVVRRENIVGDAM---EVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRK 605
Query: 607 EFFQLIVEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVN 666
EFF LI+ E+ +P YGMF + +DSR +WF+ +FE F LIG++ GLAIYN I+ ++
Sbjct: 606 EFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLH 665
Query: 667 FPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTN 726
FP+ +Y+KLL +K S +DL + P + ++ +L+Y DD+EE + F I ++ FG
Sbjct: 666 FPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVEN-FGAT 724
Query: 727 MFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFR 786
EL +NG + V ++N++EFVD Y D++ N SV + F AF GF V L F+
Sbjct: 725 EVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVL-LLFQ 783
Query: 787 PEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTG 846
P E++ +V G+ +D+ ELEK+TEY G Y ++ ++ FW + H LPLE K++ L F TG
Sbjct: 784 PNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTG 843
Query: 847 SDRVPVGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKG 906
SDR+P+ G+ +L VI G + LP +HTCFN+L LP+Y ++ L+ +L++AI++++G
Sbjct: 844 SDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEG 903
Query: 907 FGL 909
F L
Sbjct: 904 FSL 906
>AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 303 bits (743), Expect = 2e-81
Identities = 173/483 (35%), Positives = 273/483 (56%), Gaps = 22/483 (4%)
Query: 444 PSSMKGARNSQLNDPLAV-ELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC------E 496
P S + NS L+ L V E+ V + + ++ FY + ++I++ D +
Sbjct: 429 PPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQ 488
Query: 497 DYEMVISRPNTRFSFL-----RHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXX 551
Y M ++ T + + +PFV +K+ L + L+M
Sbjct: 489 AYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLF 548
Query: 552 RP-----EPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSK 606
P P L L VRR +++ DA+ E++ + +D KK L V F GE VD GGV K
Sbjct: 549 LPVIESVNPCLILVVRRENIVGDAM---EVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRK 605
Query: 607 EFFQLIVEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVN 666
EFF LI+ E+ +P YGMF + +DSR +WF+ +FE F LIG++ GLAIYN I+ ++
Sbjct: 606 EFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLH 665
Query: 667 FPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTN 726
FP+ +Y+KLL +K S +DL + P + ++ +L+Y DD+EE + F I ++ FG
Sbjct: 666 FPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVEN-FGAT 724
Query: 727 MFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFR 786
EL +NG + V ++N++EFVD Y D++ N SV + F AF GF V L F+
Sbjct: 725 EVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVL-LLFQ 783
Query: 787 PEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTG 846
P E++ +V G+ +D+ ELEK+TEY G Y ++ ++ FW + H LPLE K++ L F TG
Sbjct: 784 PNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTG 843
Query: 847 SDRVPVGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKG 906
SDR+P+ G+ +L VI G + LP +HTCFN+L LP+Y ++ L+ +L++AI++++G
Sbjct: 844 SDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEG 903
Query: 907 FGL 909
F L
Sbjct: 904 FSL 906
>AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein.
Length = 953
Score = 303 bits (743), Expect = 2e-81
Identities = 173/483 (35%), Positives = 273/483 (56%), Gaps = 22/483 (4%)
Query: 444 PSSMKGARNSQLNDPLAV-ELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC------E 496
P S + NS L+ L V E+ V + + ++ FY + ++I++ D +
Sbjct: 475 PPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQ 534
Query: 497 DYEMVISRPNTRFSFL-----RHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXX 551
Y M ++ T + + +PFV +K+ L + L+M
Sbjct: 535 AYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLF 594
Query: 552 RP-----EPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSK 606
P P L L VRR +++ DA+ E++ + +D KK L V F GE VD GGV K
Sbjct: 595 LPVIESVNPCLILVVRRENIVGDAM---EVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRK 651
Query: 607 EFFQLIVEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVN 666
EFF LI+ E+ +P YGMF + +DSR +WF+ +FE F LIG++ GLAIYN I+ ++
Sbjct: 652 EFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLH 711
Query: 667 FPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTN 726
FP+ +Y+KLL +K S +DL + P + ++ +L+Y DD+EE + F I ++ FG
Sbjct: 712 FPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVEN-FGAT 770
Query: 727 MFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFR 786
EL +NG + V ++N++EFVD Y D++ N SV + F AF GF V L F+
Sbjct: 771 EVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVL-LLFQ 829
Query: 787 PEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTG 846
P E++ +V G+ +D+ ELEK+TEY G Y ++ ++ FW + H LPLE K++ L F TG
Sbjct: 830 PNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTG 889
Query: 847 SDRVPVGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKG 906
SDR+P+ G+ +L VI G + LP +HTCFN+L LP+Y ++ L+ +L++AI++++G
Sbjct: 890 SDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEG 949
Query: 907 FGL 909
F L
Sbjct: 950 FSL 952
>D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.
Length = 1054
Score = 299 bits (733), Expect = 4e-80
Identities = 148/355 (41%), Positives = 224/355 (63%), Gaps = 5/355 (1%)
Query: 555 PFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVE 614
PFL L VRR++L+ DAL +S+ +DLKK L V F+GE+ VD GGV+KEFF L+++
Sbjct: 704 PFLVLHVRRNNLVGDAL---RELSIHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLK 760
Query: 615 EIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRK 674
E+ NP YGMFT+ QDS +WF+ T F F LIGI GLAIYN+ ++ ++FP+ +Y+K
Sbjct: 761 ELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKK 820
Query: 675 LLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVN 734
LL K EDL + +P L+++L+Y G+D+EE + F IC ++ +G +L
Sbjct: 821 LLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTIC-RESYGVIEQKKLIPG 879
Query: 735 GDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLV 794
GDN+ V ++N++EFVD Y +++ +SV + AF GFL V L F+P E+ ++
Sbjct: 880 GDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVL-ELFQPSELRAMM 938
Query: 795 CGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGG 854
G+ +++ ELE++ Y G Y++ V+ FW H PLE K+K L F TGSDR+P+ G
Sbjct: 939 VGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYG 998
Query: 855 LCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
+ +L VI + LP AHTC+N+L LP+Y +++ L RL +A++ +GF L
Sbjct: 999 MASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFSL 1053
Score = 35.1 bits (77), Expect = 1.1
Identities = 37/163 (22%), Positives = 67/163 (41%), Gaps = 5/163 (3%)
Query: 259 PQLDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDAVNCFVITF 318
P +D+ S R F+ K+ +S L L S S L L S +E A+ ++I
Sbjct: 460 PGIDLNSTRVLFE---KLMNSQHSMILEQILNSFESCLIPQLSSSPPDVE-AMRIYLILP 515
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E P L S Y+ + +AI L L WSQ C ++ + + L +
Sbjct: 516 EFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAV-LYL 574
Query: 379 VSCNYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLH 421
+ V + ++T ++L+ LY ++ ++ +T +
Sbjct: 575 LRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFY 617
>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
protein.
Length = 1024
Score = 243 bits (595), Expect = 2e-63
Identities = 140/405 (34%), Positives = 218/405 (53%), Gaps = 16/405 (3%)
Query: 511 FLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPE------PFLRLRVRRS 564
F PF+ SK L+ + L++ S+ E P L VRR+
Sbjct: 629 FSHFPFIFNNLSKIKLLHTDTLLKIESKKHKAYLRSAAIEEERESEFALRPTFDLTVRRN 688
Query: 565 HLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMF 624
HLIED L L E DL+K+L V F GE G D GGV KEFF + E+ P+YGMF
Sbjct: 689 HLIEDVLNQLSQFENE---DLRKELWVSFSGEIGYDLGGVKKEFFYCLFAEMIQPEYGMF 745
Query: 625 THQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFED 684
+ + + +WF + ++ G++ GL+++N + + FP+ +++KLL + S ED
Sbjct: 746 MYPEGASCMWFPVKPKFEKKRYFFFGVLCGLSLFNCNVANLPFPLALFKKLLDQMPSLED 805
Query: 685 LVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQEN 744
L + +P L L+ +L+ GD+ EEV+Y F + + D TN+ NG +I V Q N
Sbjct: 806 LKELSPDLGKNLQTLLDDEGDNFEEVFYIHFNV-HWDRNDTNLI----PNGSSITVNQTN 860
Query: 745 KKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHE 804
K+++V Y +++ N SV+ + FRRGF + DE + F PEE++ ++ G+ +D+
Sbjct: 861 KRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDII-KLFHPEELKDVIVGNTDYDWKT 919
Query: 805 LEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVIAR 864
EK+ Y+ GY S + FW H L LE+K+K L F TG+DR+ + L N+
Sbjct: 920 FEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMKITFCC 979
Query: 865 NGPDCDRLP-TAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFG 908
+R P A TCF+VL LP+Y T + +++ L +AIN ++GFG
Sbjct: 980 PESWNERDPIRALTCFSVLFLPKYSTMETVEEALQEAINNNRGFG 1024
>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
protein.
Length = 1024
Score = 243 bits (595), Expect = 2e-63
Identities = 140/405 (34%), Positives = 218/405 (53%), Gaps = 16/405 (3%)
Query: 511 FLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPE------PFLRLRVRRS 564
F PF+ SK L+ + L++ S+ E P L VRR+
Sbjct: 629 FSHFPFIFNNLSKIKLLHTDTLLKIESKKHKAYLRSAAIEEERESEFALRPTFDLTVRRN 688
Query: 565 HLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMF 624
HLIED L L E DL+K+L V F GE G D GGV KEFF + E+ P+YGMF
Sbjct: 689 HLIEDVLNQLSQFENE---DLRKELWVSFSGEIGYDLGGVKKEFFYCLFAEMIQPEYGMF 745
Query: 625 THQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFED 684
+ + + +WF + ++ G++ GL+++N + + FP+ +++KLL + S ED
Sbjct: 746 MYPEGASCMWFPVKPKFEKKRYFFFGVLCGLSLFNCNVANLPFPLALFKKLLDQMPSLED 805
Query: 685 LVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQEN 744
L + +P L L+ +L+ GD+ EEV+Y F + + D TN+ NG +I V Q N
Sbjct: 806 LKELSPDLGKNLQTLLDDEGDNFEEVFYIHFNV-HWDRNDTNLI----PNGSSITVNQTN 860
Query: 745 KKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHE 804
K+++V Y +++ N SV+ + FRRGF + DE + F PEE++ ++ G+ +D+
Sbjct: 861 KRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDII-KLFHPEELKDVIVGNTDYDWKT 919
Query: 805 LEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVIAR 864
EK+ Y+ GY S + FW H L LE+K+K L F TG+DR+ + L N+
Sbjct: 920 FEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMKITFCC 979
Query: 865 NGPDCDRLP-TAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFG 908
+R P A TCF+VL LP+Y T + +++ L +AIN ++GFG
Sbjct: 980 PESWNERDPIRALTCFSVLFLPKYSTMETVEEALQEAINNNRGFG 1024
>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
protein.
Length = 1022
Score = 228 bits (557), Expect = 8e-59
Identities = 137/406 (33%), Positives = 219/406 (53%), Gaps = 20/406 (4%)
Query: 511 FLRHPFVLTVASKSLGLYYENRLRMY-SESRXXXXXXXXXXXR-----PEPFLRLRVRRS 564
F PF+ SK L ++ ++M SE + + P P LRVRRS
Sbjct: 620 FSDFPFIFNSLSKIKLLQADSHIKMQMSEKKAYMLMHETILQKKDEFPPSPRFILRVRRS 679
Query: 565 HLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMF 624
L++DAL +S A D K LVVEF E + GGVS EFF + EE+ P+YGMF
Sbjct: 680 RLVKDAL---RQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMF 736
Query: 625 THQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFED 684
+ + +WF + ++ L G++ GL+++N + + FP+ +Y+KLL +K S ED
Sbjct: 737 MYPEMGSCMWFPAKPKPEKKRYFLFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLED 796
Query: 685 LVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY--QDVFGTNMFHELKVNGDNIFVTQ 742
L + +P L L+++L+ DD+ + F I + DV +L NG +I V Q
Sbjct: 797 LKELSPRLGKSLQEVLDDAADDIGDALCIRFSIHWDQNDV-------DLIPNGISIPVDQ 849
Query: 743 ENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDF 802
NK+++V Y D++ NVSV+ + F+RGF V ++ L F+ PEE+ + G+ +D+
Sbjct: 850 TNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFY-PEELMTAIIGNTDYDW 908
Query: 803 HELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVI 862
+ E++++Y+ GY +Q FW H L L++K+K L F TG DR+ G+ + V
Sbjct: 909 KQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVF 968
Query: 863 ARNGPDCDR-LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGF 907
+R PT+ TC N+L LP+Y T +++++ L AIN ++GF
Sbjct: 969 RCPETFSERDHPTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 1014
>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
Length = 1022
Score = 228 bits (557), Expect = 8e-59
Identities = 137/406 (33%), Positives = 219/406 (53%), Gaps = 20/406 (4%)
Query: 511 FLRHPFVLTVASKSLGLYYENRLRMY-SESRXXXXXXXXXXXR-----PEPFLRLRVRRS 564
F PF+ SK L ++ ++M SE + + P P LRVRRS
Sbjct: 620 FSDFPFIFNSLSKIKLLQADSHIKMQMSEKKAYMLMHETILQKKDEFPPSPRFILRVRRS 679
Query: 565 HLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMF 624
L++DAL +S A D K LVVEF E + GGVS EFF + EE+ P+YGMF
Sbjct: 680 RLVKDAL---RQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMF 736
Query: 625 THQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFED 684
+ + +WF + ++ L G++ GL+++N + + FP+ +Y+KLL +K S ED
Sbjct: 737 MYPEMGSCMWFPAKPKPEKKRYFLFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLED 796
Query: 685 LVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY--QDVFGTNMFHELKVNGDNIFVTQ 742
L + +P L L+++L+ DD+ + F I + DV +L NG +I V Q
Sbjct: 797 LKELSPRLGKSLQEVLDDAADDIGDALCIRFSIHWDQNDV-------DLIPNGISIPVDQ 849
Query: 743 ENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDF 802
NK+++V Y D++ NVSV+ + F+RGF V ++ L F+ PEE+ + G+ +D+
Sbjct: 850 TNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFY-PEELMTAIIGNTDYDW 908
Query: 803 HELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVI 862
+ E++++Y+ GY +Q FW H L L++K+K L F TG DR+ G+ + V
Sbjct: 909 KQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVF 968
Query: 863 ARNGPDCDR-LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGF 907
+R PT+ TC N+L LP+Y T +++++ L AIN ++GF
Sbjct: 969 RCPETFSERDHPTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 1014
>BC035775-1|AAH35775.2| 396|Homo sapiens HERC6 protein protein.
Length = 396
Score = 227 bits (556), Expect = 1e-58
Identities = 128/358 (35%), Positives = 203/358 (56%), Gaps = 14/358 (3%)
Query: 553 PEPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLI 612
P P LRVRRS L++DAL +S A D K LVVEF E + GGVS EFF +
Sbjct: 42 PSPRFILRVRRSRLVKDAL---RQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCM 98
Query: 613 VEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
EE+ P+YGMF + + +WF + ++ L G++ GL+++N + + FP+ +Y
Sbjct: 99 FEEMTKPEYGMFMYPEMGSCMWFPAKPKPEKKRYFLFGMLCGLSLFNLNVANLPFPLALY 158
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY--QDVFGTNMFHE 730
+KLL +K S EDL + +P L L+++L+ DD+ + F I + DV +
Sbjct: 159 KKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCIRFSIHWDQNDV-------D 211
Query: 731 LKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEV 790
L NG +I V Q NK+++V Y D++ NVSV+ + F+RGF V ++ L F+ PEE+
Sbjct: 212 LIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFY-PEEL 270
Query: 791 EMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRV 850
+ G+ +D+ + E++++Y+ GY +Q FW H L L++K+K L F TG DR+
Sbjct: 271 MTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRL 330
Query: 851 PVGGLCNLNFVIARNGPDCDR-LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGF 907
G+ + V +R PT+ TC N+L LP+Y T +++++ L AIN ++GF
Sbjct: 331 HARGIQKMEIVFRCPETFSERDHPTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 388
>AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant
protein.
Length = 986
Score = 227 bits (556), Expect = 1e-58
Identities = 128/358 (35%), Positives = 203/358 (56%), Gaps = 14/358 (3%)
Query: 553 PEPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLI 612
P P LRVRRS L++DAL +S A D K LVVEF E + GGVS EFF +
Sbjct: 632 PSPRFILRVRRSRLVKDAL---RQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCM 688
Query: 613 VEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
EE+ P+YGMF + + +WF + ++ L G++ GL+++N + + FP+ +Y
Sbjct: 689 FEEMTKPEYGMFMYPEMGSCMWFPAKPKPEKKRYFLFGMLCGLSLFNLNVANLPFPLALY 748
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY--QDVFGTNMFHE 730
+KLL +K S EDL + +P L L+++L+ DD+ + F I + DV +
Sbjct: 749 KKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCIRFSIHWDQNDV-------D 801
Query: 731 LKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEV 790
L NG +I V Q NK+++V Y D++ NVSV+ + F+RGF V ++ L F+ PEE+
Sbjct: 802 LIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFY-PEEL 860
Query: 791 EMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRV 850
+ G+ +D+ + E++++Y+ GY +Q FW H L L++K+K L F TG DR+
Sbjct: 861 MTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRL 920
Query: 851 PVGGLCNLNFVIARNGPDCDR-LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGF 907
G+ + V +R PT+ TC N+L LP+Y T +++++ L AIN ++GF
Sbjct: 921 HARGIQKMEIVFRCPETFSERDHPTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 978
>AK000644-1|BAA91303.1| 379|Homo sapiens protein ( Homo sapiens
cDNA FLJ20637 fis, clone KAT03212. ).
Length = 379
Score = 227 bits (555), Expect = 1e-58
Identities = 128/358 (35%), Positives = 203/358 (56%), Gaps = 14/358 (3%)
Query: 553 PEPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLI 612
P P LRVRRS L++DAL +S A D K LVVEF E + GGVS EFF +
Sbjct: 25 PSPRFILRVRRSRLVKDAL---RQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCM 81
Query: 613 VEEIFNPDYGMFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
EE+ P+YGMF + + +WF + ++ L G++ GL+++N + + FP+ +Y
Sbjct: 82 FEEMTKPEYGMFMYPEMCSCMWFPAKPKPEKKRYFLFGMLCGLSLFNLNVANLPFPLALY 141
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY--QDVFGTNMFHE 730
+KLL +K S EDL + +P L L+++L+ DD+ + F I + DV +
Sbjct: 142 KKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCIRFSIHWDQNDV-------D 194
Query: 731 LKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEV 790
L NG +I V Q NK+++V Y D++ NVSV+ + F+RGF V ++ L F+ PEE+
Sbjct: 195 LIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFY-PEEL 253
Query: 791 EMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRV 850
+ G+ +D+ + E++++Y+ GY +Q FW H L L++K+K L F TG DR+
Sbjct: 254 MTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRL 313
Query: 851 PVGGLCNLNFVIARNGPDCDR-LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGF 907
G+ + V +R PT+ TC N+L LP+Y T +++++ L AIN ++GF
Sbjct: 314 HARGIQKMEIVFRCPETFSERDHPTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 371
>AL713675-1|CAD28480.1| 238|Homo sapiens hypothetical protein
protein.
Length = 238
Score = 213 bits (521), Expect = 2e-54
Identities = 109/227 (48%), Positives = 149/227 (65%), Gaps = 4/227 (1%)
Query: 683 EDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQ 742
+DL P L +GL ++L + G+ +EE +Y TF++ +Q+ FG + LK GD I VT
Sbjct: 15 DDLCQIMPELAHGLSELLSHEGN-VEEDFYSTFQV-FQEEFGIIKSYNLKPGGDKISVTN 72
Query: 743 ENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDF 802
+N+KE+V LY DFLLN S+ QF AF GF V + L RPEEVE+LVCGS D
Sbjct: 73 QNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNAL-MLLRPEEVEILVCGSPDLDM 131
Query: 803 HELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVI 862
H L++ST+YDG YA ++ FW +V PL+ ++KLL FTTGSDRVPVGG+ +LNF I
Sbjct: 132 HALQRSTQYDG-YAKTDLTIKYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLNFKI 190
Query: 863 ARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
++N + LP AHTCFN L LP Y ++ L+ +L+ I+ S+GFGL
Sbjct: 191 SKNETSTNCLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGL 237
>AJ001108-1|CAA04535.1| 415|Homo sapiens E6-AP ubiquitin-protein
ligase protein.
Length = 415
Score = 209 bits (511), Expect = 3e-53
Identities = 122/317 (38%), Positives = 181/317 (57%), Gaps = 17/317 (5%)
Query: 261 LDVASCRRAFQYLAKVPTEYYSTDLVIALKSLGSYLSKDLKSEKLSIEDA--VNCFVITF 318
+D+ + RR + L + E T + AL L + DL + D +N F+I
Sbjct: 110 VDIDAIRRVYTRL--LSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIGM 167
Query: 319 ELPNLGCSDYFEIALPDVCLAIGELPIKGQARLARIWSQYCKDSLRNILETLQQLISLRV 378
E NL +Y E+ALP C A+ +LP+ Q +L R+WS+Y D +R ++ET QQLI+ +V
Sbjct: 168 ENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKV 227
Query: 379 VSCNYHVFFHVQEDGHVTGPTRVLKVLYYASILAGVLDSNTLH---EEPIVIAHQHDPLE 435
+S ++ V +D + ++ LK++YYA+++ G +D+N EEPI + + L+
Sbjct: 228 ISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSEL-TLQ 286
Query: 436 SVLGHLYPPSSMKGARNSQLNDPLAVELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC 495
+LG + KG R DPL ELGV LD R P +PFE+F NEPL++V+EMDK
Sbjct: 287 ELLGE--ERRNKKGPR----VDPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDK-- 338
Query: 496 EDYEMVISRPNTRFSFLRHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXXRPEP 555
DY +FSF+ PF+L +K+LGLYY+NR+RMYSE R + P
Sbjct: 339 -DYTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNP 397
Query: 556 FLRLRVRRSHLIEDALV 572
+LRL+VRR H+I+DALV
Sbjct: 398 YLRLKVRRDHIIDDALV 414
>Z97054-12|CAI42656.1| 3407|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 3407
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 3050 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 3106
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 3107 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 3166
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 3167 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 3222
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 3223 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 3281
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 3282 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 3340
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 3341 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 3400
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 3401 SEGFGL 3406
>Z97054-10|CAI42654.1| 4374|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 4374
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 4017 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 4073
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 4074 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 4133
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 4134 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 4189
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 4190 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 4248
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 4249 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 4307
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 4308 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 4367
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 4368 SEGFGL 4373
>Z97054-1|CAI42644.1| 1196|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 1196
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 839 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 895
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 896 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 955
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 956 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 1011
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 1012 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 1070
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 1071 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 1129
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 1130 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 1189
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 1190 SEGFGL 1195
>Z94044-4|CAI42354.1| 4374|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 4374
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 4017 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 4073
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 4074 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 4133
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 4134 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 4189
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 4190 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 4248
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 4249 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 4307
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 4308 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 4367
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 4368 SEGFGL 4373
>DQ097177-1|AAY98258.1| 4374|Homo sapiens Mcl-1 ubiquitin ligase
protein.
Length = 4374
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 4017 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 4073
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 4074 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 4133
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 4134 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 4189
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 4190 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 4248
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 4249 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 4307
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 4308 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 4367
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 4368 SEGFGL 4373
>BC063505-1|AAH63505.1| 388|Homo sapiens HUWE1 protein protein.
Length = 388
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 31 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 87
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 88 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 147
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 148 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 203
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 204 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 262
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 263 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 321
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 322 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 381
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 382 SEGFGL 387
>AY929612-1|AAX24125.1| 4374|Homo sapiens LASU1 protein.
Length = 4374
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 4017 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 4073
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 4074 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 4133
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 4134 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 4189
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 4190 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 4248
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 4249 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 4307
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 4308 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 4367
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 4368 SEGFGL 4373
>AY772009-1|AAV90838.1| 4374|Homo sapiens ARF-binding protein 1
protein.
Length = 4374
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 4017 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 4073
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 4074 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 4133
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 4134 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 4189
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 4190 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 4248
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 4249 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 4307
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 4308 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 4367
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 4368 SEGFGL 4373
>AL592046-4|CAI39581.1| 3407|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 3407
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 3050 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 3106
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 3107 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 3166
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 3167 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 3222
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 3223 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 3281
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 3282 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 3340
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 3341 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 3400
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 3401 SEGFGL 3406
>AL592046-3|CAI39580.1| 4374|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 4374
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 4017 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 4073
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 4074 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 4133
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 4134 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 4189
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 4190 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 4248
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 4249 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 4307
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 4308 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 4367
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 4368 SEGFGL 4373
>AL592046-1|CAI39578.1| 1196|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 1196
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 839 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 895
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 896 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 955
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 956 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 1011
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 1012 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 1070
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 1071 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 1129
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 1130 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 1189
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 1190 SEGFGL 1195
>AB071605-1|BAC06833.1| 3360|Homo sapiens HECT domain protein LASU1
protein.
Length = 3360
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 3003 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 3059
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 3060 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 3119
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 3120 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 3175
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 3176 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 3234
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 3235 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 3293
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 3294 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 3353
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 3354 SEGFGL 3359
>AB002310-1|BAA20771.2| 3192|Homo sapiens KIAA0312 protein.
Length = 3192
Score = 206 bits (503), Expect = 3e-52
Identities = 132/366 (36%), Positives = 197/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 2835 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 2891
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 2892 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 2951
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 2952 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 3007
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 3008 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 3066
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 3067 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 3125
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 3126 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 3185
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 3186 SEGFGL 3191
>AK223167-1|BAD96887.1| 439|Homo sapiens E3 ubiquitin protein
ligase URE-B1 variant protein.
Length = 439
Score = 206 bits (502), Expect = 4e-52
Identities = 132/366 (36%), Positives = 196/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + VRR H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 82 MAVHVRRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 138
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 139 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 198
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 199 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 254
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 255 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 313
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 314 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 372
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL LL AI
Sbjct: 373 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLHHMLLLAIQEC 432
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 433 SEGFGL 438
>BC002602-1|AAH02602.2| 442|Homo sapiens HUWE1 protein protein.
Length = 442
Score = 203 bits (496), Expect = 2e-51
Identities = 131/366 (35%), Positives = 196/366 (53%), Gaps = 22/366 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+ + V R H+ ED+ L S E ++K +L + FEGE+G D GG+ +E++ +I E+
Sbjct: 85 MAVHVLRDHVFEDSYRELHRKSPE---EMKNRLYIVFEGEEGQDAGGLLREWYMIISREM 141
Query: 617 FNPDYGMF-THQQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP Y +F T D NP+S + F +G ++ A+Y+N +L F Y
Sbjct: 142 FNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFY 201
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGTNMFHEL 731
+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG +L
Sbjct: 202 KHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGVCEVRDL 257
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F +E+E
Sbjct: 258 KPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIFTEQELE 316
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF TG+ +VP
Sbjct: 317 LLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 375
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI-NY 903
+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL AI
Sbjct: 376 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 435
Query: 904 SKGFGL 909
S+GFGL
Sbjct: 436 SEGFGL 441
>D42055-1|BAA07655.1| 927|Homo sapiens KIAA0093 protein.
Length = 927
Score = 200 bits (488), Expect = 2e-50
Identities = 123/367 (33%), Positives = 207/367 (56%), Gaps = 22/367 (5%)
Query: 553 PEPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLI 612
P F +++RR+ ++ED+ ++ ++RA LK +L +EF+GE+G+D GGV++E+F LI
Sbjct: 567 PNKF-EMKLRRATVLEDSY--RRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLI 623
Query: 613 VEEIFNPDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNF 667
+E+FNP YG+F + D+ + NP S + + F IG V G+A+Y+ +L F
Sbjct: 624 SKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFF 683
Query: 668 PMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNM 727
Y+ +L + + D+ + YN L+ +LE +L+ + I +++FG
Sbjct: 684 IRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPTELDLRF-----IIDEELFGQTH 738
Query: 728 FHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRP 787
HELK G I VT +NKKE++ L + ++ Q AF+ GF + + L F
Sbjct: 739 QHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQD-LIKIFDE 797
Query: 788 EEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
E+E+L+CG D ++ + T+Y GY+++ +++Q FW V + E + +LLQF TG+
Sbjct: 798 NELELLMCGLGDVDVNDWREHTKYKNGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGT 857
Query: 848 DRVPVGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKA 900
RVP+ G L +F + + G ++LP AHTCFN L LP Y++ ++L D+L A
Sbjct: 858 SRVPMNGFAELYGSNGPQSFTVEQWGTP-EKLPRAHTCFNRLDLPPYESFEELWDKLQMA 916
Query: 901 INYSKGF 907
I ++GF
Sbjct: 917 IENTQGF 923
>AY550969-1|AAT52215.1| 900|Homo sapiens cell
proliferation-inducing protein 53 protein.
Length = 900
Score = 200 bits (488), Expect = 2e-50
Identities = 123/367 (33%), Positives = 207/367 (56%), Gaps = 22/367 (5%)
Query: 553 PEPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLI 612
P F +++RR+ ++ED+ ++ ++RA LK +L +EF+GE+G+D GGV++E+F LI
Sbjct: 540 PNKF-EMKLRRATVLEDSY--RRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLI 596
Query: 613 VEEIFNPDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNF 667
+E+FNP YG+F + D+ + NP S + + F IG V G+A+Y+ +L F
Sbjct: 597 SKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFF 656
Query: 668 PMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNM 727
Y+ +L + + D+ + YN L+ +LE +L+ + I +++FG
Sbjct: 657 IRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPTELDLRF-----IIDEELFGQTH 711
Query: 728 FHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRP 787
HELK G I VT +NKKE++ L + ++ Q AF+ GF + + L F
Sbjct: 712 QHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQD-LIKIFDE 770
Query: 788 EEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
E+E+L+CG D ++ + T+Y GY+++ +++Q FW V + E + +LLQF TG+
Sbjct: 771 NELELLMCGLGDVDVNDWREHTKYKNGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGT 830
Query: 848 DRVPVGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKA 900
RVP+ G L +F + + G ++LP AHTCFN L LP Y++ ++L D+L A
Sbjct: 831 SRVPMNGFAELYGSNGPQSFTVEQWGTP-EKLPRAHTCFNRLDLPPYESFEELWDKLQMA 889
Query: 901 INYSKGF 907
I ++GF
Sbjct: 890 IENTQGF 896
>AF464850-1|AAM90910.1| 757|Homo sapiens Smad-ubiquitin E3 ligase
Smurf1-beta protein.
Length = 757
Score = 200 bits (487), Expect = 2e-50
Identities = 126/366 (34%), Positives = 201/366 (54%), Gaps = 23/366 (6%)
Query: 558 RLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIF 617
R+ V R + E++ I R DLKK+L+V+F GE+G+D GGV++E+ L+ E+
Sbjct: 400 RIEVSREEIFEESY---RQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEML 456
Query: 618 NPDYGMFTHQQDS-RNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
NP YG+F + D+ + NP S + + F +G ++GLA+++ + F + Y+
Sbjct: 457 NPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYK 516
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKV 733
+LLG+ DL +P L+ L +LE +D+ V TF + + FG + HELK
Sbjct: 517 QLLGKPIQLSDLESVDPELHKSLVWILE---NDITPVLDHTFCV-EHNAFGRILQHELKP 572
Query: 734 NGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEML 793
NG N+ VT+ENKKE+V LY ++ +E QF A ++GF + + L F + +E+E++
Sbjct: 573 NGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQ-KELELI 631
Query: 794 VCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVG 853
+ G D ++ + +T A DS IV+ FW V + E + +LLQF TGS RVP+
Sbjct: 632 IGGLDKIDLNDWKSNTRLKHCVA-DSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQ 690
Query: 854 GLCNLNFVIARNGP----------DCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINY 903
G L GP + D LP AHTCFN + +P Y++ +KL ++LL A+
Sbjct: 691 GFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEE 750
Query: 904 SKGFGL 909
+ GF +
Sbjct: 751 TCGFAV 756
>AF199364-1|AAF08298.2| 722|Homo sapiens E3 ubiquitin ligase SMURF1
protein.
Length = 722
Score = 200 bits (487), Expect = 2e-50
Identities = 126/366 (34%), Positives = 201/366 (54%), Gaps = 23/366 (6%)
Query: 558 RLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIF 617
R+ V R + E++ I R DLKK+L+V+F GE+G+D GGV++E+ L+ E+
Sbjct: 365 RIEVSREEIFEESY---RQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEML 421
Query: 618 NPDYGMFTHQQDS-RNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
NP YG+F + D+ + NP S + + F +G ++GLA+++ + F + Y+
Sbjct: 422 NPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYK 481
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKV 733
+LLG+ DL +P L+ L +LE +D+ V TF + + FG + HELK
Sbjct: 482 QLLGKPIQLSDLESVDPELHKSLVWILE---NDITPVLDHTFCV-EHNAFGRILQHELKP 537
Query: 734 NGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEML 793
NG N+ VT+ENKKE+V LY ++ +E QF A ++GF + + L F + +E+E++
Sbjct: 538 NGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQ-KELELI 596
Query: 794 VCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVG 853
+ G D ++ + +T A DS IV+ FW V + E + +LLQF TGS RVP+
Sbjct: 597 IGGLDKIDLNDWKSNTRLKHCVA-DSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQ 655
Query: 854 GLCNLNFVIARNGP----------DCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINY 903
G L GP + D LP AHTCFN + +P Y++ +KL ++LL A+
Sbjct: 656 GFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEE 715
Query: 904 SKGFGL 909
+ GF +
Sbjct: 716 TCGFAV 721
>AC004893-2|AAC62434.1| 712|Homo sapiens WUGSC:H_DJ0808A01.2
protein.
Length = 712
Score = 200 bits (487), Expect = 2e-50
Identities = 126/366 (34%), Positives = 201/366 (54%), Gaps = 23/366 (6%)
Query: 558 RLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIF 617
R+ V R + E++ I R DLKK+L+V+F GE+G+D GGV++E+ L+ E+
Sbjct: 355 RIEVSREEIFEESY---RQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEML 411
Query: 618 NPDYGMFTHQQDS-RNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
NP YG+F + D+ + NP S + + F +G ++GLA+++ + F + Y+
Sbjct: 412 NPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYK 471
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKV 733
+LLG+ DL +P L+ L +LE +D+ V TF + + FG + HELK
Sbjct: 472 QLLGKPIQLSDLESVDPELHKSLVWILE---NDITPVLDHTFCV-EHNAFGRILQHELKP 527
Query: 734 NGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEML 793
NG N+ VT+ENKKE+V LY ++ +E QF A ++GF + + L F + +E+E++
Sbjct: 528 NGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQ-KELELI 586
Query: 794 VCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVG 853
+ G D ++ + +T A DS IV+ FW V + E + +LLQF TGS RVP+
Sbjct: 587 IGGLDKIDLNDWKSNTRLKHCVA-DSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQ 645
Query: 854 GLCNLNFVIARNGP----------DCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINY 903
G L GP + D LP AHTCFN + +P Y++ +KL ++LL A+
Sbjct: 646 GFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEE 705
Query: 904 SKGFGL 909
+ GF +
Sbjct: 706 TCGFAV 711
>AB046845-1|BAB13451.1| 859|Homo sapiens KIAA1625 protein protein.
Length = 859
Score = 200 bits (487), Expect = 2e-50
Identities = 126/366 (34%), Positives = 201/366 (54%), Gaps = 23/366 (6%)
Query: 558 RLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIF 617
R+ V R + E++ I R DLKK+L+V+F GE+G+D GGV++E+ L+ E+
Sbjct: 502 RIEVSREEIFEESY---RQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEML 558
Query: 618 NPDYGMFTHQQDS-RNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
NP YG+F + D+ + NP S + + F +G ++GLA+++ + F + Y+
Sbjct: 559 NPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYK 618
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKV 733
+LLG+ DL +P L+ L +LE +D+ V TF + + FG + HELK
Sbjct: 619 QLLGKPIQLSDLESVDPELHKSLVWILE---NDITPVLDHTFCV-EHNAFGRILQHELKP 674
Query: 734 NGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEML 793
NG N+ VT+ENKKE+V LY ++ +E QF A ++GF + + L F + +E+E++
Sbjct: 675 NGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQ-KELELI 733
Query: 794 VCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVG 853
+ G D ++ + +T A DS IV+ FW V + E + +LLQF TGS RVP+
Sbjct: 734 IGGLDKIDLNDWKSNTRLKHCVA-DSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQ 792
Query: 854 GLCNLNFVIARNGP----------DCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINY 903
G L GP + D LP AHTCFN + +P Y++ +KL ++LL A+
Sbjct: 793 GFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEE 852
Query: 904 SKGFGL 909
+ GF +
Sbjct: 853 TCGFAV 858
>U96114-1|AAC51325.1| 870|Homo sapiens WWP2 protein.
Length = 870
Score = 199 bits (485), Expect = 4e-50
Identities = 123/365 (33%), Positives = 205/365 (56%), Gaps = 24/365 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + I + DL+++L + GE+G+D GG+++E+F L+ E+
Sbjct: 515 VKISVSRQTLFEDSF---QQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEV 571
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +++ + NP S + F IG + +A+Y+ + F + Y
Sbjct: 572 LNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFY 631
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L ++ + +DL +P YN + + E ++LEE + + I ++ G HELK
Sbjct: 632 KRMLNKRPTLKDLESIDPEFYNSIVWIKE---NNLEECGLELYFIQDMEILGKVTTHELK 688
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
G++I VT+ENK+E++ L D+ VE Q +AF GF V L +F +E+E+
Sbjct: 689 EGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWL-RYFDEKELEL 747
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++CG + D + +KST Y Y +SK +Q FW +V + E + +LLQF TG+ R+PV
Sbjct: 748 MLCGMQEIDMSDWQKSTIY-RHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPV 806
Query: 853 GGLCNLNFVIARNGPD--C-DR------LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINY 903
GG L I NGP C D+ LP +HTCFN L LP Y + ++L+++LL AI
Sbjct: 807 GGFAEL---IGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEE 863
Query: 904 SKGFG 908
++GFG
Sbjct: 864 TEGFG 868
>BC064531-1|AAH64531.1| 870|Homo sapiens WWP2 protein protein.
Length = 870
Score = 199 bits (485), Expect = 4e-50
Identities = 123/365 (33%), Positives = 205/365 (56%), Gaps = 24/365 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + I + DL+++L + GE+G+D GG+++E+F L+ E+
Sbjct: 515 VKISVSRQTLFEDSF---QQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEV 571
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +++ + NP S + F IG + +A+Y+ + F + Y
Sbjct: 572 LNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFY 631
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L ++ + +DL +P YN + + E ++LEE + + I ++ G HELK
Sbjct: 632 KRMLNKRPTLKDLESIDPEFYNSIVWIKE---NNLEECGLELYFIQDMEILGKVTTHELK 688
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
G++I VT+ENK+E++ L D+ VE Q +AF GF V L +F +E+E+
Sbjct: 689 EGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWL-RYFDEKELEL 747
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++CG + D + +KST Y Y +SK +Q FW +V + E + +LLQF TG+ R+PV
Sbjct: 748 MLCGMQEIDMSDWQKSTIY-RHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPV 806
Query: 853 GGLCNLNFVIARNGPD--C-DR------LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINY 903
GG L I NGP C D+ LP +HTCFN L LP Y + ++L+++LL AI
Sbjct: 807 GGFAEL---IGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEE 863
Query: 904 SKGFG 908
++GFG
Sbjct: 864 TEGFG 868
>BC013645-1|AAH13645.1| 870|Homo sapiens WW domain containing E3
ubiquitin protein ligase 2 protein.
Length = 870
Score = 199 bits (485), Expect = 4e-50
Identities = 123/365 (33%), Positives = 205/365 (56%), Gaps = 24/365 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + I + DL+++L + GE+G+D GG+++E+F L+ E+
Sbjct: 515 VKISVSRQTLFEDSF---QQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEV 571
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +++ + NP S + F IG + +A+Y+ + F + Y
Sbjct: 572 LNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFY 631
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L ++ + +DL +P YN + + E ++LEE + + I ++ G HELK
Sbjct: 632 KRMLNKRPTLKDLESIDPEFYNSIVWIKE---NNLEECGLELYFIQDMEILGKVTTHELK 688
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
G++I VT+ENK+E++ L D+ VE Q +AF GF V L +F +E+E+
Sbjct: 689 EGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWL-RYFDEKELEL 747
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++CG + D + +KST Y Y +SK +Q FW +V + E + +LLQF TG+ R+PV
Sbjct: 748 MLCGMQEIDMSDWQKSTIY-RHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPV 806
Query: 853 GGLCNLNFVIARNGPD--C-DR------LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINY 903
GG L I NGP C D+ LP +HTCFN L LP Y + ++L+++LL AI
Sbjct: 807 GGFAEL---IGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEE 863
Query: 904 SKGFG 908
++GFG
Sbjct: 864 TEGFG 868
>BC011571-1|AAH11571.1| 903|Homo sapiens ITCH protein protein.
Length = 903
Score = 199 bits (485), Expect = 4e-50
Identities = 120/363 (33%), Positives = 206/363 (56%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + S + DL+++L V F GE+G+D GGV++E+F L+ E+
Sbjct: 548 IKITVTRKTLFEDSFQQIMSFSPQ---DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEV 604
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +D+ + NP S+ + F IG + +A+++ + F + Y
Sbjct: 605 LNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY 664
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L + +DL +P YN L + E +++EE + + +++ G H+LK
Sbjct: 665 KRILNKPVGLKDLESIDPEFYNSLIWVKE---NNIEECDLEMYFSVDKEILGEIKSHDLK 721
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG NI VT+ENK+E++ + A++ L+ VE Q +AF GF + + L +F +E+E+
Sbjct: 722 PNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYL-QYFDAKELEV 780
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG + D ++ ++ Y YA SK + FW V + E + +LLQF TG+ R+PV
Sbjct: 781 LLCGMQEIDLNDWQRHAIY-RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPV 839
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG +L F I + G + + LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 840 GGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 898
Query: 906 GFG 908
GFG
Sbjct: 899 GFG 901
>AL356299-4|CAI17960.1| 862|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 862
Score = 199 bits (485), Expect = 4e-50
Identities = 120/363 (33%), Positives = 206/363 (56%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + S + DL+++L V F GE+G+D GGV++E+F L+ E+
Sbjct: 507 IKITVTRKTLFEDSFQQIMSFSPQ---DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEV 563
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +D+ + NP S+ + F IG + +A+++ + F + Y
Sbjct: 564 LNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY 623
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L + +DL +P YN L + E +++EE + + +++ G H+LK
Sbjct: 624 KRILNKPVGLKDLESIDPEFYNSLIWVKE---NNIEECDLEMYFSVDKEILGEIKSHDLK 680
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG NI VT+ENK+E++ + A++ L+ VE Q +AF GF + + L +F +E+E+
Sbjct: 681 PNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYL-QYFDAKELEV 739
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG + D ++ ++ Y YA SK + FW V + E + +LLQF TG+ R+PV
Sbjct: 740 LLCGMQEIDLNDWQRHAIY-RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPV 798
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG +L F I + G + + LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 799 GGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 857
Query: 906 GFG 908
GFG
Sbjct: 858 GFG 860
>AL356299-3|CAI17959.1| 903|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 903
Score = 199 bits (485), Expect = 4e-50
Identities = 120/363 (33%), Positives = 206/363 (56%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + S + DL+++L V F GE+G+D GGV++E+F L+ E+
Sbjct: 548 IKITVTRKTLFEDSFQQIMSFSPQ---DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEV 604
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +D+ + NP S+ + F IG + +A+++ + F + Y
Sbjct: 605 LNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY 664
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L + +DL +P YN L + E +++EE + + +++ G H+LK
Sbjct: 665 KRILNKPVGLKDLESIDPEFYNSLIWVKE---NNIEECDLEMYFSVDKEILGEIKSHDLK 721
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG NI VT+ENK+E++ + A++ L+ VE Q +AF GF + + L +F +E+E+
Sbjct: 722 PNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYL-QYFDAKELEV 780
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG + D ++ ++ Y YA SK + FW V + E + +LLQF TG+ R+PV
Sbjct: 781 LLCGMQEIDLNDWQRHAIY-RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPV 839
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG +L F I + G + + LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 840 GGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 898
Query: 906 GFG 908
GFG
Sbjct: 899 GFG 901
>AL109923-6|CAI21458.1| 903|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 903
Score = 199 bits (485), Expect = 4e-50
Identities = 120/363 (33%), Positives = 206/363 (56%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + S + DL+++L V F GE+G+D GGV++E+F L+ E+
Sbjct: 548 IKITVTRKTLFEDSFQQIMSFSPQ---DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEV 604
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +D+ + NP S+ + F IG + +A+++ + F + Y
Sbjct: 605 LNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY 664
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L + +DL +P YN L + E +++EE + + +++ G H+LK
Sbjct: 665 KRILNKPVGLKDLESIDPEFYNSLIWVKE---NNIEECDLEMYFSVDKEILGEIKSHDLK 721
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG NI VT+ENK+E++ + A++ L+ VE Q +AF GF + + L +F +E+E+
Sbjct: 722 PNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYL-QYFDAKELEV 780
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG + D ++ ++ Y YA SK + FW V + E + +LLQF TG+ R+PV
Sbjct: 781 LLCGMQEIDLNDWQRHAIY-RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPV 839
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG +L F I + G + + LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 840 GGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 898
Query: 906 GFG 908
GFG
Sbjct: 899 GFG 901
>AL109923-5|CAI21459.1| 862|Homo sapiens itchy homolog E3 ubiquitin
protein ligase (mouse) protein.
Length = 862
Score = 199 bits (485), Expect = 4e-50
Identities = 120/363 (33%), Positives = 206/363 (56%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + S + DL+++L V F GE+G+D GGV++E+F L+ E+
Sbjct: 507 IKITVTRKTLFEDSFQQIMSFSPQ---DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEV 563
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +D+ + NP S+ + F IG + +A+++ + F + Y
Sbjct: 564 LNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY 623
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L + +DL +P YN L + E +++EE + + +++ G H+LK
Sbjct: 624 KRILNKPVGLKDLESIDPEFYNSLIWVKE---NNIEECDLEMYFSVDKEILGEIKSHDLK 680
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG NI VT+ENK+E++ + A++ L+ VE Q +AF GF + + L +F +E+E+
Sbjct: 681 PNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYL-QYFDAKELEV 739
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG + D ++ ++ Y YA SK + FW V + E + +LLQF TG+ R+PV
Sbjct: 740 LLCGMQEIDLNDWQRHAIY-RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPV 798
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG +L F I + G + + LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 799 GGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 857
Query: 906 GFG 908
GFG
Sbjct: 858 GFG 860
>AF095745-1|AAK39399.1| 862|Homo sapiens ubiquitin protein ligase
ITCH protein.
Length = 862
Score = 199 bits (485), Expect = 4e-50
Identities = 120/363 (33%), Positives = 206/363 (56%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + S + DL+++L V F GE+G+D GGV++E+F L+ E+
Sbjct: 507 IKITVTRKTLFEDSFQQIMSFSPQ---DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEV 563
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +D+ + NP S+ + F IG + +A+++ + F + Y
Sbjct: 564 LNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY 623
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L + +DL +P YN L + E +++EE + + +++ G H+LK
Sbjct: 624 KRILNKPVGLKDLESIDPEFYNSLIWVKE---NNIEECDLEMYFSVDKEILGEIKSHDLK 680
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG NI VT+ENK+E++ + A++ L+ VE Q +AF GF + + L +F +E+E+
Sbjct: 681 PNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYL-QYFDAKELEV 739
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG + D ++ ++ Y YA SK + FW V + E + +LLQF TG+ R+PV
Sbjct: 740 LLCGMQEIDLNDWQRHAIY-RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPV 798
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG +L F I + G + + LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 799 GGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 857
Query: 906 GFG 908
GFG
Sbjct: 858 GFG 860
>AF038564-1|AAC04845.1| 739|Homo sapiens atrophin-1 interacting
protein 4 protein.
Length = 739
Score = 199 bits (485), Expect = 4e-50
Identities = 120/363 (33%), Positives = 206/363 (56%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + S + DL+++L V F GE+G+D GGV++E+F L+ E+
Sbjct: 384 IKITVTRKTLFEDSFQQIMSFSPQ---DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEV 440
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +D+ + NP S+ + F IG + +A+++ + F + Y
Sbjct: 441 LNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY 500
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L + +DL +P YN L + E +++EE + + +++ G H+LK
Sbjct: 501 KRILNKPVGLKDLESIDPEFYNSLIWVKE---NNIEECDLEMYFSVDKEILGEIKSHDLK 557
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG NI VT+ENK+E++ + A++ L+ VE Q +AF GF + + L +F +E+E+
Sbjct: 558 PNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYL-QYFDAKELEV 616
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG + D ++ ++ Y YA SK + FW V + E + +LLQF TG+ R+PV
Sbjct: 617 LLCGMQEIDLNDWQRHAIY-RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPV 675
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG +L F I + G + + LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 676 GGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 734
Query: 906 GFG 908
GFG
Sbjct: 735 GFG 737
>AB209747-1|BAD92984.1| 605|Homo sapiens itchy homolog E3 ubiquitin
protein ligase variant protein.
Length = 605
Score = 199 bits (485), Expect = 4e-50
Identities = 120/363 (33%), Positives = 206/363 (56%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + S + DL+++L V F GE+G+D GGV++E+F L+ E+
Sbjct: 250 IKITVTRKTLFEDSFQQIMSFSPQ---DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEV 306
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +D+ + NP S+ + F IG + +A+++ + F + Y
Sbjct: 307 LNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY 366
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L + +DL +P YN L + E +++EE + + +++ G H+LK
Sbjct: 367 KRILNKPVGLKDLESIDPEFYNSLIWVKE---NNIEECDLEMYFSVDKEILGEIKSHDLK 423
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG NI VT+ENK+E++ + A++ L+ VE Q +AF GF + + L +F +E+E+
Sbjct: 424 PNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYL-QYFDAKELEV 482
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG + D ++ ++ Y YA SK + FW V + E + +LLQF TG+ R+PV
Sbjct: 483 LLCGMQEIDLNDWQRHAIY-RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPV 541
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG +L F I + G + + LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 542 GGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 600
Query: 906 GFG 908
GFG
Sbjct: 601 GFG 603
>AB056663-1|BAB39389.1| 862|Homo sapiens ubiquitin protein ligase
Itch protein.
Length = 862
Score = 199 bits (485), Expect = 4e-50
Identities = 120/363 (33%), Positives = 206/363 (56%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + S + DL+++L V F GE+G+D GGV++E+F L+ E+
Sbjct: 507 IKITVTRKTLFEDSFQQIMSFSPQ---DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEV 563
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +D+ + NP S+ + F IG + +A+++ + F + Y
Sbjct: 564 LNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY 623
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L + +DL +P YN L + E +++EE + + +++ G H+LK
Sbjct: 624 KRILNKPVGLKDLESIDPEFYNSLIWVKE---NNIEECDLEMYFSVDKEILGEIKSHDLK 680
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG NI VT+ENK+E++ + A++ L+ VE Q +AF GF + + L +F +E+E+
Sbjct: 681 PNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYL-QYFDAKELEV 739
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG + D ++ ++ Y YA SK + FW V + E + +LLQF TG+ R+PV
Sbjct: 740 LLCGMQEIDLNDWQRHAIY-RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPV 798
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG +L F I + G + + LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 799 GGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 857
Query: 906 GFG 908
GFG
Sbjct: 858 GFG 860
>BC111945-1|AAI11946.1| 748|Homo sapiens SMAD specific E3 ubiquitin
protein ligase 2 protein.
Length = 748
Score = 195 bits (475), Expect = 7e-49
Identities = 122/363 (33%), Positives = 200/363 (55%), Gaps = 20/363 (5%)
Query: 558 RLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIF 617
R+ V R + E++ + R DL K+L+++F GE+G+D GGV++E+ L+ E+
Sbjct: 394 RIEVSREEIFEESY---RQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEML 450
Query: 618 NPDYGMFTHQQDS-RNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
NP YG+F + +D + NP S E + F +G ++G+A+++ + F + Y+
Sbjct: 451 NPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYK 510
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKV 733
+LLG+ + +D+ +P L+N L +LE +D+ V TF + + +G + HELK
Sbjct: 511 QLLGKSITLDDMELVDPDLHNSLVWILE---NDITGVLDHTFCV-EHNAYGEIIQHELKP 566
Query: 734 NGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEML 793
NG +I V +ENKKE+V LY ++ +E QF A ++GF V + L F +E+E++
Sbjct: 567 NGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKT-FDEKELELI 625
Query: 794 VCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVG 853
+CG D ++ + +T DS IV+ FW V E + +LLQF TGS RVP+
Sbjct: 626 ICGLGKIDVNDWKVNTRLK-HCTPDSNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQ 684
Query: 854 GLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKG 906
G L F I + + LP AHTCFN + +P Y++ +KL ++LL AI + G
Sbjct: 685 GFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCG 744
Query: 907 FGL 909
F +
Sbjct: 745 FAV 747
>BC093876-1|AAH93876.1| 748|Homo sapiens SMAD specific E3 ubiquitin
protein ligase 2 protein.
Length = 748
Score = 195 bits (475), Expect = 7e-49
Identities = 122/363 (33%), Positives = 200/363 (55%), Gaps = 20/363 (5%)
Query: 558 RLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIF 617
R+ V R + E++ + R DL K+L+++F GE+G+D GGV++E+ L+ E+
Sbjct: 394 RIEVSREEIFEESY---RQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEML 450
Query: 618 NPDYGMFTHQQDS-RNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
NP YG+F + +D + NP S E + F +G ++G+A+++ + F + Y+
Sbjct: 451 NPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYK 510
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKV 733
+LLG+ + +D+ +P L+N L +LE +D+ V TF + + +G + HELK
Sbjct: 511 QLLGKSITLDDMELVDPDLHNSLVWILE---NDITGVLDHTFCV-EHNAYGEIIQHELKP 566
Query: 734 NGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEML 793
NG +I V +ENKKE+V LY ++ +E QF A ++GF V + L F +E+E++
Sbjct: 567 NGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKT-FDEKELELI 625
Query: 794 VCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVG 853
+CG D ++ + +T DS IV+ FW V E + +LLQF TGS RVP+
Sbjct: 626 ICGLGKIDVNDWKVNTRLK-HCTPDSNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQ 684
Query: 854 GLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKG 906
G L F I + + LP AHTCFN + +P Y++ +KL ++LL AI + G
Sbjct: 685 GFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCG 744
Query: 907 FGL 909
F +
Sbjct: 745 FAV 747
>AY014180-1|AAG50421.1| 748|Homo sapiens E3 ubiquitin ligase Smurf2
protein.
Length = 748
Score = 195 bits (475), Expect = 7e-49
Identities = 122/363 (33%), Positives = 200/363 (55%), Gaps = 20/363 (5%)
Query: 558 RLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIF 617
R+ V R + E++ + R DL K+L+++F GE+G+D GGV++E+ L+ E+
Sbjct: 394 RIEVSREEIFEESY---RQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEML 450
Query: 618 NPDYGMFTHQQDS-RNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
NP YG+F + +D + NP S E + F +G ++G+A+++ + F + Y+
Sbjct: 451 NPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYK 510
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKV 733
+LLG+ + +D+ +P L+N L +LE +D+ V TF + + +G + HELK
Sbjct: 511 QLLGKSITLDDMELVDPDLHNSLVWILE---NDITGVLDHTFCV-EHNAYGEIIQHELKP 566
Query: 734 NGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEML 793
NG +I V +ENKKE+V LY ++ +E QF A ++GF V + L F +E+E++
Sbjct: 567 NGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKT-FDEKELELI 625
Query: 794 VCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVG 853
+CG D ++ + +T DS IV+ FW V E + +LLQF TGS RVP+
Sbjct: 626 ICGLGKIDVNDWKVNTRLK-HCTPDSNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQ 684
Query: 854 GLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKG 906
G L F I + + LP AHTCFN + +P Y++ +KL ++LL AI + G
Sbjct: 685 GFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCG 744
Query: 907 FGL 909
F +
Sbjct: 745 FAV 747
>AF310676-1|AAG45422.1| 748|Homo sapiens E3 ubiquitin ligase SMURF2
protein.
Length = 748
Score = 195 bits (475), Expect = 7e-49
Identities = 122/363 (33%), Positives = 200/363 (55%), Gaps = 20/363 (5%)
Query: 558 RLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIF 617
R+ V R + E++ + R DL K+L+++F GE+G+D GGV++E+ L+ E+
Sbjct: 394 RIEVSREEIFEESY---RQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEML 450
Query: 618 NPDYGMFTHQQDS-RNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
NP YG+F + +D + NP S E + F +G ++G+A+++ + F + Y+
Sbjct: 451 NPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYK 510
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKV 733
+LLG+ + +D+ +P L+N L +LE +D+ V TF + + +G + HELK
Sbjct: 511 QLLGKSITLDDMELVDPDLHNSLVWILE---NDITGVLDHTFCV-EHNAYGEIIQHELKP 566
Query: 734 NGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEML 793
NG +I V +ENKKE+V LY ++ +E QF A ++GF V + L F +E+E++
Sbjct: 567 NGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKT-FDEKELELI 625
Query: 794 VCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVG 853
+CG D ++ + +T DS IV+ FW V E + +LLQF TGS RVP+
Sbjct: 626 ICGLGKIDVNDWKVNTRLK-HCTPDSNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQ 684
Query: 854 GLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKG 906
G L F I + + LP AHTCFN + +P Y++ +KL ++LL AI + G
Sbjct: 685 GFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCG 744
Query: 907 FGL 909
F +
Sbjct: 745 FAV 747
>AF301463-1|AAG25641.1| 748|Homo sapiens ubiquitin E3 ligase SMURF2
protein.
Length = 748
Score = 195 bits (475), Expect = 7e-49
Identities = 122/363 (33%), Positives = 200/363 (55%), Gaps = 20/363 (5%)
Query: 558 RLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIF 617
R+ V R + E++ + R DL K+L+++F GE+G+D GGV++E+ L+ E+
Sbjct: 394 RIEVSREEIFEESY---RQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEML 450
Query: 618 NPDYGMFTHQQDS-RNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
NP YG+F + +D + NP S E + F +G ++G+A+++ + F + Y+
Sbjct: 451 NPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYK 510
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKV 733
+LLG+ + +D+ +P L+N L +LE +D+ V TF + + +G + HELK
Sbjct: 511 QLLGKSITLDDMELVDPDLHNSLVWILE---NDITGVLDHTFCV-EHNAYGEIIQHELKP 566
Query: 734 NGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEML 793
NG +I V +ENKKE+V LY ++ +E QF A ++GF V + L F +E+E++
Sbjct: 567 NGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKT-FDEKELELI 625
Query: 794 VCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVG 853
+CG D ++ + +T DS IV+ FW V E + +LLQF TGS RVP+
Sbjct: 626 ICGLGKIDVNDWKVNTRLK-HCTPDSNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQ 684
Query: 854 GLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKG 906
G L F I + + LP AHTCFN + +P Y++ +KL ++LL AI + G
Sbjct: 685 GFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCG 744
Query: 907 FGL 909
F +
Sbjct: 745 FAV 747
>DQ181796-1|ABA10330.1| 834|Homo sapiens NEDD4L variant protein.
Length = 834
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 479 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 536
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 537 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 596
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 597 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 650
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 651 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 709
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 710 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 769
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 770 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 828
Query: 906 GF 907
GF
Sbjct: 829 GF 830
>BC032597-1|AAH32597.1| 911|Homo sapiens NEDD4L protein protein.
Length = 911
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 556 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 613
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 614 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 673
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 674 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 727
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 728 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 786
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 787 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 846
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 847 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 905
Query: 906 GF 907
GF
Sbjct: 906 GF 907
>BC019345-1|AAH19345.1| 855|Homo sapiens Unknown (protein for
IMAGE:3604024) protein.
Length = 855
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 500 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 557
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 558 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 617
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 618 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 671
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 672 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 730
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 731 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 790
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 791 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 849
Query: 906 GF 907
GF
Sbjct: 850 GF 851
>BC000621-1|AAH00621.2| 855|Homo sapiens NEDD4L protein protein.
Length = 855
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 500 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 557
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 558 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 617
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 618 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 671
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 672 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 730
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 731 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 790
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 791 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 849
Query: 906 GF 907
GF
Sbjct: 850 GF 851
>AY312514-1|AAP75706.1| 975|Homo sapiens NEDD4.2 protein.
Length = 975
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 620 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 677
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 678 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 737
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 738 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 791
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 792 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 850
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 851 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 910
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 911 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 969
Query: 906 GF 907
GF
Sbjct: 970 GF 971
>AY112985-1|AAM76730.1| 947|Homo sapiens ubiquitin ligase NEDD4h
protein.
Length = 947
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 592 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 649
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 650 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 709
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 710 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 763
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 764 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 822
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 823 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 882
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 883 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 941
Query: 906 GF 907
GF
Sbjct: 942 GF 943
>AY112984-1|AAM76729.1| 967|Homo sapiens ubiquitin ligase NEDD4g
protein.
Length = 967
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 612 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 669
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 670 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 729
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 730 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 783
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 784 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 842
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 843 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 902
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 903 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 961
Query: 906 GF 907
GF
Sbjct: 962 GF 963
>AY112983-1|AAM76728.1| 854|Homo sapiens ubiquitin ligase NEDD4f
protein.
Length = 854
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 499 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 556
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 557 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 616
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 617 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 670
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 671 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 729
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 730 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 789
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 790 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 848
Query: 906 GF 907
GF
Sbjct: 849 GF 850
>AL137469-1|CAB70754.1| 820|Homo sapiens hypothetical protein
protein.
Length = 820
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 465 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 522
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 523 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 582
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 583 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 636
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 637 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 695
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 696 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 755
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 756 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 814
Query: 906 GF 907
GF
Sbjct: 815 GF 816
>AF385931-1|AAM46208.1| 854|Homo sapiens ubiquitin ligase NEDD4Lb
protein.
Length = 854
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 499 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 556
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 557 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 616
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 617 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 670
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 671 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 729
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 730 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 789
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 790 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 848
Query: 906 GF 907
GF
Sbjct: 849 GF 850
>AF210730-1|AAG43524.1| 854|Homo sapiens NEDD4La protein.
Length = 854
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 499 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 556
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 557 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 616
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 617 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 670
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 671 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 729
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 730 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 789
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 790 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 848
Query: 906 GF 907
GF
Sbjct: 849 GF 850
>AB071179-1|BAB69424.1| 955|Homo sapiens NEDD4-like ubiquitin
ligase 3 protein.
Length = 955
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 600 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 657
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 658 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 717
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 718 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 771
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 772 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 830
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 831 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 890
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 891 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 949
Query: 906 GF 907
GF
Sbjct: 950 GF 951
>AB007899-1|BAA23711.1| 995|Homo sapiens KIAA0439 protein.
Length = 995
Score = 194 bits (474), Expect = 9e-49
Identities = 122/362 (33%), Positives = 201/362 (55%), Gaps = 23/362 (6%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFN 618
+++ R+++ E++ ++S++R LK +L +EFE E+G+D GGV++E+F L+ +E+FN
Sbjct: 640 MKLHRNNIFEESY--RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN 697
Query: 619 PDYGMFTHQQ-DSRNVWFNPTSF----ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYR 673
P YG+F + D+ + NP S + + FT IG V GLA+++ +L F Y+
Sbjct: 698 PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYK 757
Query: 674 KLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICY-QDVFGTNMFHELK 732
+LG++ + D+ + YN LK +LE +L+ ++ C ++ FG +LK
Sbjct: 758 MMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMF------CIDEENFGQTYQVDLK 811
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
NG I VT ENK+E++DL + V+ Q AF GF + L F E+E+
Sbjct: 812 PNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPID-LIKIFDENELEL 870
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
L+CG D ++ + + Y GY + ++Q FW V + E + +LLQF TG+ RVP+
Sbjct: 871 LMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPM 930
Query: 853 GGLCNLN-------FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G ++LP AHTCFN L LP Y+T + L+++LL A+ ++
Sbjct: 931 NGFAELYGSNGPQLFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQ 989
Query: 906 GF 907
GF
Sbjct: 990 GF 991
>BC107576-1|AAI07577.1| 332|Homo sapiens HUWE1 protein protein.
Length = 332
Score = 193 bits (471), Expect = 2e-48
Identities = 122/335 (36%), Positives = 181/335 (54%), Gaps = 19/335 (5%)
Query: 588 QLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMF-THQQDSRNVWFNPTSFETE--- 643
+L + FEGE+G D GG+ +E++ +I E+FNP Y +F T D NP+S
Sbjct: 3 RLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHL 62
Query: 644 AQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYT 703
+ F +G ++ A+Y+N +L F Y+ +LG+ + D+ + Y GL +LE
Sbjct: 63 SYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLE-- 120
Query: 704 GDDLEEVYYQ-TFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVE 762
+D+ + Y TF Q+ FG +LK NG NI VT+ENKKE+V L + ++
Sbjct: 121 -NDVSTLGYDLTFSTEVQE-FGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIR 178
Query: 763 TQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIV 822
Q AF GF + + L + F +E+E+L+ G D +L+ +TEY Y S+S +
Sbjct: 179 KQLAAFLEGFYEIIPKR-LISIFTEQELELLISGLPTIDIDDLKSNTEYH-KYQSNSIQI 236
Query: 823 QDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNL-------NFVIARNGPDCDRLPTA 875
Q FW + S D+ K LQF TG+ +VP+ G L F I R+ DRLP+A
Sbjct: 237 QWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSA 296
Query: 876 HTCFNVLLLPEYDTRDKLQDRLLKAI-NYSKGFGL 909
HTCFN L LP Y++ +KL+ LL AI S+GFGL
Sbjct: 297 HTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFGL 331
>BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 909
Score = 189 bits (461), Expect = 3e-47
Identities = 114/338 (33%), Positives = 178/338 (52%), Gaps = 15/338 (4%)
Query: 575 EMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMFTHQQDSRNVW 634
E++S LK+ + V F GE+G+ +G V +E+F ++ EI NPDY +FT D
Sbjct: 568 EVVSKANCAKLKQGIAVRFHGEEGMGQG-VVREWFDILSNEIVNPDYALFTQSADGTTFQ 626
Query: 635 FNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPI 691
N S+ F G +LGLA+ + ++ + F Y+ +LG +++D+ +P
Sbjct: 627 PNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPE 686
Query: 692 LYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDL 751
L+ +L+ +D+ ++ + DVFG LK G +I VTQ NK E+V L
Sbjct: 687 YAKNLQWILD---NDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQL 743
Query: 752 YADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEY 811
+ + +++ Q AF +GF M S L F E+E+L+ G D + K+TEY
Sbjct: 744 VTELRMTRAIQPQINAFLQGFHMFIPPS-LIQLFDEYELELLLSGMPEIDVSDWIKNTEY 802
Query: 812 DGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNL-------NFVIAR 864
GY + ++Q FW +V + E++ LLQF TGS RVP GG N+ NF IA
Sbjct: 803 TSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAA 862
Query: 865 NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAIN 902
+ LPT+ TC N+L LPEY +++ L+DRLL A++
Sbjct: 863 VPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH 900
>AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 189 bits (461), Expect = 3e-47
Identities = 114/338 (33%), Positives = 178/338 (52%), Gaps = 15/338 (4%)
Query: 575 EMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMFTHQQDSRNVW 634
E++S LK+ + V F GE+G+ +G V +E+F ++ EI NPDY +FT D
Sbjct: 562 EVVSKANCAKLKQGIAVRFHGEEGMGQG-VVREWFDILSNEIVNPDYALFTQSADGTTFQ 620
Query: 635 FNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPI 691
N S+ F G +LGLA+ + ++ + F Y+ +LG +++D+ +P
Sbjct: 621 PNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPE 680
Query: 692 LYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDL 751
L+ +L+ +D+ ++ + DVFG LK G +I VTQ NK E+V L
Sbjct: 681 YAKNLQWILD---NDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQL 737
Query: 752 YADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEY 811
+ + +++ Q AF +GF M S L F E+E+L+ G D + K+TEY
Sbjct: 738 VTELRMTRAIQPQINAFLQGFHMFIPPS-LIQLFDEYELELLLSGMPEIDVSDWIKNTEY 796
Query: 812 DGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNL-------NFVIAR 864
GY + ++Q FW +V + E++ LLQF TGS RVP GG N+ NF IA
Sbjct: 797 TSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAA 856
Query: 865 NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAIN 902
+ LPT+ TC N+L LPEY +++ L+DRLL A++
Sbjct: 857 VPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH 894
>AL590402-1|CAH74023.1| 562|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 562
Score = 189 bits (461), Expect = 3e-47
Identities = 114/338 (33%), Positives = 178/338 (52%), Gaps = 15/338 (4%)
Query: 575 EMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMFTHQQDSRNVW 634
E++S LK+ + V F GE+G+ +G V +E+F ++ EI NPDY +FT D
Sbjct: 221 EVVSKANCAKLKQGIAVRFHGEEGMGQG-VVREWFDILSNEIVNPDYALFTQSADGTTFQ 279
Query: 635 FNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPI 691
N S+ F G +LGLA+ + ++ + F Y+ +LG +++D+ +P
Sbjct: 280 PNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPE 339
Query: 692 LYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDL 751
L+ +L+ +D+ ++ + DVFG LK G +I VTQ NK E+V L
Sbjct: 340 YAKNLQWILD---NDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQL 396
Query: 752 YADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEY 811
+ + +++ Q AF +GF M S L F E+E+L+ G D + K+TEY
Sbjct: 397 VTELRMTRAIQPQINAFLQGFHMFIPPS-LIQLFDEYELELLLSGMPEIDVSDWIKNTEY 455
Query: 812 DGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNL-------NFVIAR 864
GY + ++Q FW +V + E++ LLQF TGS RVP GG N+ NF IA
Sbjct: 456 TSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAA 515
Query: 865 NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAIN 902
+ LPT+ TC N+L LPEY +++ L+DRLL A++
Sbjct: 516 VPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH 553
>AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 189 bits (461), Expect = 3e-47
Identities = 114/338 (33%), Positives = 178/338 (52%), Gaps = 15/338 (4%)
Query: 575 EMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMFTHQQDSRNVW 634
E++S LK+ + V F GE+G+ +G V +E+F ++ EI NPDY +FT D
Sbjct: 562 EVVSKANCAKLKQGIAVRFHGEEGMGQG-VVREWFDILSNEIVNPDYALFTQSADGTTFQ 620
Query: 635 FNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPI 691
N S+ F G +LGLA+ + ++ + F Y+ +LG +++D+ +P
Sbjct: 621 PNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPE 680
Query: 692 LYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDL 751
L+ +L+ +D+ ++ + DVFG LK G +I VTQ NK E+V L
Sbjct: 681 YAKNLQWILD---NDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQL 737
Query: 752 YADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEY 811
+ + +++ Q AF +GF M S L F E+E+L+ G D + K+TEY
Sbjct: 738 VTELRMTRAIQPQINAFLQGFHMFIPPS-LIQLFDEYELELLLSGMPEIDVSDWIKNTEY 796
Query: 812 DGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNL-------NFVIAR 864
GY + ++Q FW +V + E++ LLQF TGS RVP GG N+ NF IA
Sbjct: 797 TSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAA 856
Query: 865 NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAIN 902
+ LPT+ TC N+L LPEY +++ L+DRLL A++
Sbjct: 857 VPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH 894
>AL513472-1|CAH71889.1| 562|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 562
Score = 189 bits (461), Expect = 3e-47
Identities = 114/338 (33%), Positives = 178/338 (52%), Gaps = 15/338 (4%)
Query: 575 EMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMFTHQQDSRNVW 634
E++S LK+ + V F GE+G+ +G V +E+F ++ EI NPDY +FT D
Sbjct: 221 EVVSKANCAKLKQGIAVRFHGEEGMGQG-VVREWFDILSNEIVNPDYALFTQSADGTTFQ 279
Query: 635 FNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPI 691
N S+ F G +LGLA+ + ++ + F Y+ +LG +++D+ +P
Sbjct: 280 PNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPE 339
Query: 692 LYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDL 751
L+ +L+ +D+ ++ + DVFG LK G +I VTQ NK E+V L
Sbjct: 340 YAKNLQWILD---NDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQL 396
Query: 752 YADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEY 811
+ + +++ Q AF +GF M S L F E+E+L+ G D + K+TEY
Sbjct: 397 VTELRMTRAIQPQINAFLQGFHMFIPPS-LIQLFDEYELELLLSGMPEIDVSDWIKNTEY 455
Query: 812 DGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNL-------NFVIAR 864
GY + ++Q FW +V + E++ LLQF TGS RVP GG N+ NF IA
Sbjct: 456 TSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAA 515
Query: 865 NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAIN 902
+ LPT+ TC N+L LPEY +++ L+DRLL A++
Sbjct: 516 VPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH 553
>AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 189 bits (461), Expect = 3e-47
Identities = 114/338 (33%), Positives = 178/338 (52%), Gaps = 15/338 (4%)
Query: 575 EMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMFTHQQDSRNVW 634
E++S LK+ + V F GE+G+ +G V +E+F ++ EI NPDY +FT D
Sbjct: 562 EVVSKANCAKLKQGIAVRFHGEEGMGQG-VVREWFDILSNEIVNPDYALFTQSADGTTFQ 620
Query: 635 FNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPI 691
N S+ F G +LGLA+ + ++ + F Y+ +LG +++D+ +P
Sbjct: 621 PNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPE 680
Query: 692 LYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDL 751
L+ +L+ +D+ ++ + DVFG LK G +I VTQ NK E+V L
Sbjct: 681 YAKNLQWILD---NDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQL 737
Query: 752 YADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEY 811
+ + +++ Q AF +GF M S L F E+E+L+ G D + K+TEY
Sbjct: 738 VTELRMTRAIQPQINAFLQGFHMFIPPS-LIQLFDEYELELLLSGMPEIDVSDWIKNTEY 796
Query: 812 DGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNL-------NFVIAR 864
GY + ++Q FW +V + E++ LLQF TGS RVP GG N+ NF IA
Sbjct: 797 TSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAA 856
Query: 865 NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAIN 902
+ LPT+ TC N+L LPEY +++ L+DRLL A++
Sbjct: 857 VPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH 894
>AB037741-1|BAA92558.1| 567|Homo sapiens KIAA1320 protein protein.
Length = 567
Score = 189 bits (461), Expect = 3e-47
Identities = 114/338 (33%), Positives = 178/338 (52%), Gaps = 15/338 (4%)
Query: 575 EMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPDYGMFTHQQDSRNVW 634
E++S LK+ + V F GE+G+ +G V +E+F ++ EI NPDY +FT D
Sbjct: 226 EVVSKANCAKLKQGIAVRFHGEEGMGQG-VVREWFDILSNEIVNPDYALFTQSADGTTFQ 284
Query: 635 FNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPI 691
N S+ F G +LGLA+ + ++ + F Y+ +LG +++D+ +P
Sbjct: 285 PNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPE 344
Query: 692 LYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDL 751
L+ +L+ +D+ ++ + DVFG LK G +I VTQ NK E+V L
Sbjct: 345 YAKNLQWILD---NDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQL 401
Query: 752 YADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEY 811
+ + +++ Q AF +GF M S L F E+E+L+ G D + K+TEY
Sbjct: 402 VTELRMTRAIQPQINAFLQGFHMFIPPS-LIQLFDEYELELLLSGMPEIDVSDWIKNTEY 460
Query: 812 DGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNL-------NFVIAR 864
GY + ++Q FW +V + E++ LLQF TGS RVP GG N+ NF IA
Sbjct: 461 TSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAA 520
Query: 865 NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAIN 902
+ LPT+ TC N+L LPEY +++ L+DRLL A++
Sbjct: 521 VPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH 558
>BC036065-1|AAH36065.1| 922|Homo sapiens WW domain containing E3
ubiquitin protein ligase 1 protein.
Length = 922
Score = 184 bits (449), Expect = 1e-45
Identities = 114/363 (31%), Positives = 199/363 (54%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + I + DL+++L V F GE+G+D GG+++E+F L+ E+
Sbjct: 567 VKINVSRQTLFEDSF---QQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEV 623
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +++ + NP S + + F IG + +A+++ + F + Y
Sbjct: 624 LNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFY 683
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L +K + +DL + YN L + +++EE + + ++ G H+LK
Sbjct: 684 KRMLSKKLTIKDLESIDTEFYNSL---IWIRDNNIEECGLEMYFSVDMEILGKVTSHDLK 740
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
+ G NI VT+ENK E++ L ++ + V+ Q +AF GF V L +F +E+E+
Sbjct: 741 LGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWL-QYFDEKELEV 799
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++CG + D + +++T Y Y +SK + FW V E + +LLQF TG+ R+P+
Sbjct: 800 MLCGMQEVDLADWQRNTVY-RHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPL 858
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG L F I + G D LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 859 GGFAELMGSNGPQKFCIEKVGKD-TWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 917
Query: 906 GFG 908
GFG
Sbjct: 918 GFG 920
>AY345857-1|AAQ22764.1| 922|Homo sapiens TGIF-interacting ubiquitin
ligase 1 protein.
Length = 922
Score = 184 bits (449), Expect = 1e-45
Identities = 114/363 (31%), Positives = 199/363 (54%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + I + DL+++L V F GE+G+D GG+++E+F L+ E+
Sbjct: 567 VKINVSRQTLFEDSF---QQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEV 623
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +++ + NP S + + F IG + +A+++ + F + Y
Sbjct: 624 LNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFY 683
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L +K + +DL + YN L + +++EE + + ++ G H+LK
Sbjct: 684 KRMLSKKLTIKDLESIDTEFYNSL---IWIRDNNIEECGLEMYFSVDMEILGKVTSHDLK 740
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
+ G NI VT+ENK E++ L ++ + V+ Q +AF GF V L +F +E+E+
Sbjct: 741 LGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWL-QYFDEKELEV 799
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++CG + D + +++T Y Y +SK + FW V E + +LLQF TG+ R+P+
Sbjct: 800 MLCGMQEVDLADWQRNTVY-RHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPL 858
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG L F I + G D LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 859 GGFAELMGSNGPQKFCIEKVGKD-TWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 917
Query: 906 GFG 908
GFG
Sbjct: 918 GFG 920
>AY043361-1|AAK94668.1| 922|Homo sapiens WW domain-containing
protein 1 protein.
Length = 922
Score = 184 bits (449), Expect = 1e-45
Identities = 114/363 (31%), Positives = 199/363 (54%), Gaps = 20/363 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + I + DL+++L V F GE+G+D GG+++E+F L+ E+
Sbjct: 567 VKINVSRQTLFEDSF---QQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEV 623
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +++ + NP S + + F IG + +A+++ + F + Y
Sbjct: 624 LNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFY 683
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L +K + +DL + YN L + +++EE + + ++ G H+LK
Sbjct: 684 KRMLSKKLTIKDLESIDTEFYNSL---IWIRDNNIEECGLEMYFSVDMEILGKVTSHDLK 740
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
+ G NI VT+ENK E++ L ++ + V+ Q +AF GF V L +F +E+E+
Sbjct: 741 LGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWL-QYFDEKELEV 799
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++CG + D + +++T Y Y +SK + FW V E + +LLQF TG+ R+P+
Sbjct: 800 MLCGMQEVDLADWQRNTVY-RHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPL 858
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
GG L F I + G D LP +HTCFN L LP Y + ++L+++LL AI ++
Sbjct: 859 GGFAELMGSNGPQKFCIEKVGKD-TWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETE 917
Query: 906 GFG 908
GFG
Sbjct: 918 GFG 920
>BC117198-1|AAI17199.1| 1572|Homo sapiens HECT, C2 and WW domain
containing E3 ubiquitin protein ligase 2 protein.
Length = 1572
Score = 183 bits (445), Expect = 3e-45
Identities = 120/364 (32%), Positives = 187/364 (51%), Gaps = 19/364 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
L+L +RR HL+EDA +++ R + +L V F GE+G+D G S+EFF L+ E+
Sbjct: 1216 LKLIIRRDHLLEDAFN--QIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSREL 1273
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP YG+F + D+ V +P S + F G +LGLA+ + +L F Y
Sbjct: 1274 FNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFY 1333
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+ LL DL + + L+ M + +D+ ++ TF + ++VFG ELK
Sbjct: 1334 KALLRILCDLSDLEYLDEEFHQSLQWMKD---NDIHDILDLTFTV-NEEVFGQITERELK 1389
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
G NI VT++NKKE+++ + + V Q + RGF V D + L + F E+E+
Sbjct: 1390 PGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVD-ARLVSVFDARELEL 1448
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++ G+ D + +TEY GGY + +++ FW V E + +LLQF TG+ +P
Sbjct: 1449 VIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPY 1508
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G +L F + + G LP AHTCFN L LP Y + L ++LL A+ +
Sbjct: 1509 EGFASLRGSNGPRRFCVEKWG-KITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETS 1567
Query: 906 GFGL 909
FGL
Sbjct: 1568 TFGL 1571
>BC117194-1|AAI17195.1| 1572|Homo sapiens HECT, C2 and WW domain
containing E3 ubiquitin protein ligase 2 protein.
Length = 1572
Score = 183 bits (445), Expect = 3e-45
Identities = 120/364 (32%), Positives = 187/364 (51%), Gaps = 19/364 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
L+L +RR HL+EDA +++ R + +L V F GE+G+D G S+EFF L+ E+
Sbjct: 1216 LKLIIRRDHLLEDAFN--QIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSREL 1273
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP YG+F + D+ V +P S + F G +LGLA+ + +L F Y
Sbjct: 1274 FNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFY 1333
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+ LL DL + + L+ M + +D+ ++ TF + ++VFG ELK
Sbjct: 1334 KALLRILCDLSDLEYLDEEFHQSLQWMKD---NDIHDILDLTFTV-NEEVFGQITERELK 1389
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
G NI VT++NKKE+++ + + V Q + RGF V D + L + F E+E+
Sbjct: 1390 PGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVD-ARLVSVFDARELEL 1448
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++ G+ D + +TEY GGY + +++ FW V E + +LLQF TG+ +P
Sbjct: 1449 VIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPY 1508
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G +L F + + G LP AHTCFN L LP Y + L ++LL A+ +
Sbjct: 1509 EGFASLRGSNGPRRFCVEKWG-KITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETS 1567
Query: 906 GFGL 909
FGL
Sbjct: 1568 TFGL 1571
>AB037722-1|BAA92539.1| 1581|Homo sapiens KIAA1301 protein protein.
Length = 1581
Score = 183 bits (445), Expect = 3e-45
Identities = 120/364 (32%), Positives = 187/364 (51%), Gaps = 19/364 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
L+L +RR HL+EDA +++ R + +L V F GE+G+D G S+EFF L+ E+
Sbjct: 1225 LKLIIRRDHLLEDAFN--QIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSREL 1282
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP YG+F + D+ V +P S + F G +LGLA+ + +L F Y
Sbjct: 1283 FNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFY 1342
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+ LL DL + + L+ M + +D+ ++ TF + ++VFG ELK
Sbjct: 1343 KALLRILCDLSDLEYLDEEFHQSLQWMKD---NDIHDILDLTFTV-NEEVFGQITERELK 1398
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
G NI VT++NKKE+++ + + V Q + RGF V D + L + F E+E+
Sbjct: 1399 PGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVD-ARLVSVFDARELEL 1457
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++ G+ D + +TEY GGY + +++ FW V E + +LLQF TG+ +P
Sbjct: 1458 VIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPY 1517
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G +L F + + G LP AHTCFN L LP Y + L ++LL A+ +
Sbjct: 1518 EGFASLRGSNGPRRFCVEKWG-KITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETS 1576
Query: 906 GFGL 909
FGL
Sbjct: 1577 TFGL 1580
>AB048365-1|BAB13352.1| 1585|Homo sapiens NEDD4-like ubiquitin ligase
1 protein.
Length = 1585
Score = 179 bits (436), Expect = 4e-44
Identities = 120/364 (32%), Positives = 185/364 (50%), Gaps = 19/364 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
++L +RR HL+E ++++ R + +L V F GE+G+D G S+EFF L+ +E+
Sbjct: 1229 IKLIIRRDHLLEGTFN--QVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQEL 1286
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP YG+F + D+ V +P S E F G +LGLA+ + +L F Y
Sbjct: 1287 FNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFY 1346
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+ LL DL + + L+ M + +++ ++ TF + ++VFG ELK
Sbjct: 1347 KALLRLPCDLSDLEYLDEEFHQSLQWMKD---NNITDILDLTFTV-NEEVFGQVTERELK 1402
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
G N VT++NKKE+++ + + V Q A RGF V D S L + F E+E+
Sbjct: 1403 SGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVD-SRLVSVFDARELEL 1461
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++ G+ D ++ +TEY GGY +++ FW V E + +LLQF TG+ VP
Sbjct: 1462 VIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPY 1521
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G LP AHTCFN L LP Y + L ++LL A+ +
Sbjct: 1522 EGFAALRGSNGLRRFCIEKWG-KITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETS 1580
Query: 906 GFGL 909
FGL
Sbjct: 1581 TFGL 1584
>AB002320-1|BAA20780.2| 1614|Homo sapiens KIAA0322 protein.
Length = 1614
Score = 179 bits (436), Expect = 4e-44
Identities = 120/364 (32%), Positives = 185/364 (50%), Gaps = 19/364 (5%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
++L +RR HL+E ++++ R + +L V F GE+G+D G S+EFF L+ +E+
Sbjct: 1258 IKLIIRRDHLLEGTFN--QVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQEL 1315
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVY 672
FNP YG+F + D+ V +P S E F G +LGLA+ + +L F Y
Sbjct: 1316 FNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFY 1375
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+ LL DL + + L+ M + +++ ++ TF + ++VFG ELK
Sbjct: 1376 KALLRLPCDLSDLEYLDEEFHQSLQWMKD---NNITDILDLTFTV-NEEVFGQVTERELK 1431
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
G N VT++NKKE+++ + + V Q A RGF V D S L + F E+E+
Sbjct: 1432 SGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVD-SRLVSVFDARELEL 1490
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++ G+ D ++ +TEY GGY +++ FW V E + +LLQF TG+ VP
Sbjct: 1491 VIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPY 1550
Query: 853 GGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSK 905
G L F I + G LP AHTCFN L LP Y + L ++LL A+ +
Sbjct: 1551 EGFAALRGSNGLRRFCIEKWG-KITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETS 1609
Query: 906 GFGL 909
FGL
Sbjct: 1610 TFGL 1613
>AC004975-1|AAD51453.1| 415|Homo sapiens unknown protein.
Length = 415
Score = 175 bits (426), Expect = 6e-43
Identities = 119/368 (32%), Positives = 187/368 (50%), Gaps = 23/368 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDE-----GGVSKEFFQL 611
+ + +RR+++ EDA + +S E DLKK++ V G+DE GG+ +EF
Sbjct: 55 INVTIRRNYIYEDAY---DKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNE 111
Query: 612 IVEEIFNPDYGMFTHQQDSRNVWFNPTSF-----ETEAQFTLIGIVLGLAIYNNVILAVN 666
+++ FNP+ G F + ++ NP + + +G +LG A+Y N+++ +
Sbjct: 112 LLKSGFNPNQGFFKTTNEGL-LYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELP 170
Query: 667 FPMVVYRKLLGRKGSFE--DLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFG 724
F KLLG + L +P +Y L + Y DD+EE+ F + D+ G
Sbjct: 171 FAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYE-DDVEELGLN-FTVVNNDL-G 227
Query: 725 TNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAF 784
ELK G +I VT N+ ++ L AD+ LN + AFR+G V L
Sbjct: 228 EAQVVELKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWL-RM 286
Query: 785 FRPEEVEMLVCGSKV-FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQF 843
F +E+++L+ G++V +L+ T Y GGY++D +++ FW +V E+KRKLL+F
Sbjct: 287 FDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKF 346
Query: 844 TTGSDRVPVGGLCNL--NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI 901
T R P+ G L F I G D +RLPTA TC N+L LPE+ L+ +LL AI
Sbjct: 347 VTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAI 406
Query: 902 NYSKGFGL 909
+ GF L
Sbjct: 407 ECAAGFEL 414
>D13635-1|BAA02799.2| 1086|Homo sapiens KIAA0010 protein.
Length = 1086
Score = 173 bits (420), Expect = 3e-42
Identities = 118/368 (32%), Positives = 186/368 (50%), Gaps = 23/368 (6%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDE-----GGVSKEFFQL 611
+ + +RR+++ EDA + +S E DLKK++ V G+DE GG+ +EF
Sbjct: 726 INVTIRRNYIYEDAY---DKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNE 782
Query: 612 IVEEIFNPDYGMFTHQQDSRNVWFNPTSF-----ETEAQFTLIGIVLGLAIYNNVILAVN 666
+++ FNP+ G F + ++ NP + + + +LG A+Y N+++ +
Sbjct: 783 LLKSGFNPNQGFFKTTNEGL-LYPNPAAQMLVGDSFARHYYFLARMLGKALYENMLVELP 841
Query: 667 FPMVVYRKLLGRKGSFE--DLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFG 724
F KLLG + L +P +Y L + Y DD+EE+ F + D+ G
Sbjct: 842 FAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYE-DDVEELGLN-FTVVNNDL-G 898
Query: 725 TNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAF 784
ELK G +I VT N+ ++ L AD+ LN + AFR+G V L
Sbjct: 899 EAQVVELKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWL-RM 957
Query: 785 FRPEEVEMLVCGSKV-FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQF 843
F +E+++L+ G++V +L+ T Y GGY++D +++ FW +V E+KRKLL+F
Sbjct: 958 FDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKF 1017
Query: 844 TTGSDRVPVGGLCNL--NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI 901
T R P+ G L F I G D +RLPTA TC N+L LPE+ L+ +LL AI
Sbjct: 1018 VTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAI 1077
Query: 902 NYSKGFGL 909
+ GF L
Sbjct: 1078 ECAAGFEL 1085
>CR456813-1|CAG33094.1| 308|Homo sapiens UREB1 protein.
Length = 308
Score = 169 bits (411), Expect = 4e-41
Identities = 112/312 (35%), Positives = 164/312 (52%), Gaps = 19/312 (6%)
Query: 611 LIVEEIFNPDYGMF-THQQDSRNVWFNPTSFETE---AQFTLIGIVLGLAIYNNVILAVN 666
+I E+FNP Y +F T D NP+S + F +G ++ A+Y+N +L
Sbjct: 2 IISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECY 61
Query: 667 FPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGT 725
F Y+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG
Sbjct: 62 FTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGV 117
Query: 726 NMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFF 785
+LK NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F
Sbjct: 118 CEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIF 176
Query: 786 RPEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTT 845
+E+E+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF T
Sbjct: 177 TEQELELLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVT 235
Query: 846 GSDRVPVGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLL 898
G+ +VP+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL
Sbjct: 236 GTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLL 295
Query: 899 KAI-NYSKGFGL 909
AI S+GFGL
Sbjct: 296 LAIQECSEGFGL 307
>AF057569-1|AAC62492.1| 308|Homo sapiens upstream regulatory
element binding protein 1 protein.
Length = 308
Score = 169 bits (411), Expect = 4e-41
Identities = 112/312 (35%), Positives = 164/312 (52%), Gaps = 19/312 (6%)
Query: 611 LIVEEIFNPDYGMF-THQQDSRNVWFNPTSFETE---AQFTLIGIVLGLAIYNNVILAVN 666
+I E+FNP Y +F T D NP+S + F +G ++ A+Y+N +L
Sbjct: 2 IISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECY 61
Query: 667 FPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQ-TFRICYQDVFGT 725
F Y+ +LG+ + D+ + Y GL +LE +D+ + Y TF Q+ FG
Sbjct: 62 FTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLE---NDVSTLGYDLTFSTEVQE-FGV 117
Query: 726 NMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFF 785
+LK NG NI VT+ENKKE+V L + ++ Q AF GF + + L + F
Sbjct: 118 CEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKR-LISIF 176
Query: 786 RPEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTT 845
+E+E+L+ G D +L+ +TEY Y S+S +Q FW + S D+ K LQF T
Sbjct: 177 TEQELELLISGLPTIDIDDLKSNTEYH-KYQSNSIQIQWFWRALRSFDQADRAKFLQFVT 235
Query: 846 GSDRVPVGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLL 898
G+ +VP+ G L F I R+ DRLP+AHTCFN L LP Y++ +KL+ LL
Sbjct: 236 GTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLL 295
Query: 899 KAI-NYSKGFGL 909
AI S+GFGL
Sbjct: 296 LAIQECSEGFGL 307
>AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containing
protein 4 isoform 3 protein.
Length = 979
Score = 162 bits (393), Expect = 6e-39
Identities = 77/187 (41%), Positives = 119/187 (63%), Gaps = 1/187 (0%)
Query: 723 FGTNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLG 782
FG EL +NG + V ++N++EFVD Y D++ N SV + F AF GF V L
Sbjct: 793 FGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVL- 851
Query: 783 AFFRPEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQ 842
F+P E++ +V G+ +D+ ELEK+TEY G Y ++ ++ FW + H LPLE K++ L
Sbjct: 852 LLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLL 911
Query: 843 FTTGSDRVPVGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAIN 902
F TGSDR+P+ G+ +L VI G + LP +HTCFN+L L +Y ++ L+ +L++AI+
Sbjct: 912 FLTGSDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLSKYTEKETLRSKLIQAID 971
Query: 903 YSKGFGL 909
+++GF L
Sbjct: 972 HNEGFSL 978
Score = 80.2 bits (189), Expect = 3e-14
Identities = 63/210 (30%), Positives = 100/210 (47%), Gaps = 20/210 (9%)
Query: 444 PSSMKGARNSQLNDPLAV-ELGVSVLDSRTPYLPFEDFYNEPLSDVIEMDKDC------E 496
P S + NS L+ L V E+ V + + ++ FY + ++I++ D +
Sbjct: 579 PPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQ 638
Query: 497 DYEMVISRPNTRFSFL-----RHPFVLTVASKSLGLYYENRLRMYSESRXXXXXXXXXXX 551
Y M ++ T + + +PFV +K+ L + L+M
Sbjct: 639 AYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLF 698
Query: 552 RP-----EPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSK 606
P P L L VRR +++ DA+ E++ + +D KK L V F GE VD GGV K
Sbjct: 699 LPVIESVNPCLILVVRRENIVGDAM---EVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRK 755
Query: 607 EFFQLIVEEIFNPDYGMFTHQQDSRNVWFN 636
EFF LI+ E+ +P YGMF + +DSR +WF+
Sbjct: 756 EFFLLIMRELLDPKYGMFRYYEDSRLIWFS 785
>U96113-1|AAC51324.1| 684|Homo sapiens WWP1 protein.
Length = 684
Score = 154 bits (373), Expect = 2e-36
Identities = 94/315 (29%), Positives = 170/315 (53%), Gaps = 15/315 (4%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + I + DL+++L V F GE+G+D GG+++E+F L+ E+
Sbjct: 378 VKINVSRQTLFEDSF---QQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEV 434
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +++ + NP S + + F IG + +A+++ + F + Y
Sbjct: 435 LNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFY 494
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L +K + +DL + YN L + +++EE + + ++ G H+LK
Sbjct: 495 KRMLSKKLTIKDLESIDTEFYNSL---IWIRDNNIEECGLEMYFSVDMEILGKVTSHDLK 551
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
+ G NI VT+ENK E++ L ++ + V+ Q +AF GF V L +F +E+E+
Sbjct: 552 LGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWL-QYFDEKELEV 610
Query: 793 LVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
++CG + D + +++T Y Y +SK + FW V E + +LLQF TG+ R+P+
Sbjct: 611 MLCGMQEVDLADWQRNTVY-RHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPL 669
Query: 853 GGLCNLNFVIARNGP 867
GG L + NGP
Sbjct: 670 GGFAEL---MGSNGP 681
>BC009527-1|AAH09527.1| 288|Homo sapiens SMURF2 protein protein.
Length = 288
Score = 147 bits (356), Expect = 2e-34
Identities = 97/293 (33%), Positives = 158/293 (53%), Gaps = 16/293 (5%)
Query: 627 QQDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFE 683
+ D + NP S E + F +G ++G+A+++ + F + Y++LLG+ + +
Sbjct: 1 RDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLD 60
Query: 684 DLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQE 743
D+ +P L+N L +LE +D+ V TF + + + +G + HELK NG +I V +E
Sbjct: 61 DMELVDPDLHNSLVWILE---NDITGVLDHTFCVEH-NAYGEIIQHELKPNGKSIPVNEE 116
Query: 744 NKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFH 803
NKKE+V LY ++ +E QF A ++GF V + L F +E+E+++CG D +
Sbjct: 117 NKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKT-FDEKELELIICGLGKIDVN 175
Query: 804 ELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLN---- 859
+ + +T DS IV+ FW V E + +LLQF TGS RVP+ G L
Sbjct: 176 DWKVNTRLK-HCTPDSNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQGFKALQGAAG 234
Query: 860 ---FVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
F I + + LP AHTCFN + +P Y++ +KL ++LL AI + GF +
Sbjct: 235 PRLFTIHQIDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCGFAV 287
>BC015380-1|AAH15380.2| 300|Homo sapiens WWP1 protein protein.
Length = 300
Score = 146 bits (353), Expect = 4e-34
Identities = 93/304 (30%), Positives = 162/304 (53%), Gaps = 17/304 (5%)
Query: 616 IFNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVV 671
+ NP Y +F + +++ + NP S + + F IG + +A+++ + F +
Sbjct: 1 VLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPF 60
Query: 672 YRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHEL 731
Y+++L +K + +DL + YN L + +++EE + + ++ G H+L
Sbjct: 61 YKRMLSKKLTIKDLESIDTEFYNSL---IWIRDNNIEECGLEMYFSVDMEILGKVTSHDL 117
Query: 732 KVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVE 791
K+ G NI VT+ENK E++ L ++ + V+ Q +AF GF V L +F +E+E
Sbjct: 118 KLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWL-QYFDEKELE 176
Query: 792 MLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVP 851
+++CG + D + +++T Y Y +SK + FW V E + +LLQF TG+ R+P
Sbjct: 177 VMLCGMQEVDLADWQRNTVY-RHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLP 235
Query: 852 VGGLCNL-------NFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYS 904
+GG L F I + G D LP +HTCFN L LP Y + ++L+++LL AI +
Sbjct: 236 LGGFAELMGSNGPQKFCIEKVGKD-TWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEET 294
Query: 905 KGFG 908
+GFG
Sbjct: 295 EGFG 298
>BC141880-1|AAI41881.1| 1068|Homo sapiens ubiquitin protein ligase E3B
protein.
Length = 1068
Score = 138 bits (334), Expect = 8e-32
Identities = 113/389 (29%), Positives = 175/389 (44%), Gaps = 42/389 (10%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEG--EQGVDEGGVSKEFFQLIVEEI 616
+ +RRS ++ED L +S + + V G E G+D+ GV KEF + I++ +
Sbjct: 683 ITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRV 742
Query: 617 FNPDYGMFTHQQDSRNVWFNPTSF--ETEAQ-FTLIGIVLGLAIYNNVILAVNFPMVVYR 673
F+P +F ++ +PTS+ E Q F +G +LG A+Y +++ V F
Sbjct: 743 FDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLS 802
Query: 674 KLLGRKGS-FEDLVDWNPIL----YNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMF 728
+LLG S F VD P L Y L + Y GD + ++ +DV G +
Sbjct: 803 QLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLSYD---EDVMGQLVC 859
Query: 729 HELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPE 788
HEL G I VT ENK ++ L A F ++ ++ Q A GF + + F PE
Sbjct: 860 HELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPE 919
Query: 789 EVEMLVCGSKV-FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKL-LQFTTG 846
++ L+ G D +L+K T Y GG+ +++ W I+ S D+R + L+F T
Sbjct: 920 -LQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTS 978
Query: 847 SDRVPVGGLCNL--------------------------NFVIARNGPDCDRLPTAHTCFN 880
R P+ G L F R RLPT+ TCFN
Sbjct: 979 CSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFN 1038
Query: 881 VLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
+L LP Y + L+++L AI+ + GF L
Sbjct: 1039 LLKLPNYSKKSVLREKLRYAISMNTGFEL 1067
>AF251046-1|AAK28419.2| 1068|Homo sapiens UBE3B variant 1 protein.
Length = 1068
Score = 138 bits (334), Expect = 8e-32
Identities = 113/389 (29%), Positives = 175/389 (44%), Gaps = 42/389 (10%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEG--EQGVDEGGVSKEFFQLIVEEI 616
+ +RRS ++ED L +S + + V G E G+D+ GV KEF + I++ +
Sbjct: 683 ITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRV 742
Query: 617 FNPDYGMFTHQQDSRNVWFNPTSF--ETEAQ-FTLIGIVLGLAIYNNVILAVNFPMVVYR 673
F+P +F ++ +PTS+ E Q F +G +LG A+Y +++ V F
Sbjct: 743 FDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLS 802
Query: 674 KLLGRKGS-FEDLVDWNPIL----YNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMF 728
+LLG S F VD P L Y L + Y GD + ++ +DV G +
Sbjct: 803 QLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLSYD---EDVMGQLVC 859
Query: 729 HELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPE 788
HEL G I VT ENK ++ L A F ++ ++ Q A GF + + F PE
Sbjct: 860 HELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPE 919
Query: 789 EVEMLVCGSKV-FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKL-LQFTTG 846
++ L+ G D +L+K T Y GG+ +++ W I+ S D+R + L+F T
Sbjct: 920 -LQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTS 978
Query: 847 SDRVPVGGLCNL--------------------------NFVIARNGPDCDRLPTAHTCFN 880
R P+ G L F R RLPT+ TCFN
Sbjct: 979 CSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFN 1038
Query: 881 VLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
+L LP Y + L+++L AI+ + GF L
Sbjct: 1039 LLKLPNYSKKSVLREKLRYAISMNTGFEL 1067
>AC007956-1|AAF61276.1| 823|Homo sapiens KIAA0317 protein.
Length = 823
Score = 128 bits (308), Expect = 1e-28
Identities = 103/374 (27%), Positives = 171/374 (45%), Gaps = 24/374 (6%)
Query: 552 RPEPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQL 611
RP + L+V R L+E +L S+ D K V F+ E+ +D GG +E+F+L
Sbjct: 457 RPHSKVTLKVSRHALLESSLKATRNFSIS---DWSKNFEVVFQDEEALDWGGPRREWFEL 513
Query: 612 IVEEIFNPDYGMFTHQQDSRNVWFNPTSFETE----AQFTLIGIVLGLAIYNNVI----- 662
I + +F+ +FT D+ +P + G ++G +Y + +
Sbjct: 514 ICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYK 573
Query: 663 --LAVNFPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQ 720
+ F +++G + ++ +P Y + +D+ E+ Y
Sbjct: 574 QLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFI--LNNDMSEMELVFAEEKYN 631
Query: 721 DVFGTNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESP 780
+ EL G VT NK +++L A + L V+ + F +G + E+
Sbjct: 632 KSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENL 691
Query: 781 LGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGG-YASDSKIVQDFWGIVHSLPLEDKRK 839
L A F E+E+L+CG+ + + GG + K+++ FW +V SL E+ +
Sbjct: 692 L-AIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELAR 750
Query: 840 LLQFTTGSDRVPVGG---LCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDR 896
LLQFTTGS ++P GG LC +IA P LPTAHTCFN L LP YD+ +++
Sbjct: 751 LLQFTTGSSQLPPGGFAALCPSFQIIA--APTHSTLPTAHTCFNQLCLPTYDSYEEVHRM 808
Query: 897 LLKAINYS-KGFGL 909
L AI+ +GFG+
Sbjct: 809 LQLAISEGCEGFGM 822
>AB002315-1|BAA20775.2| 826|Homo sapiens KIAA0317 protein.
Length = 826
Score = 128 bits (308), Expect = 1e-28
Identities = 103/374 (27%), Positives = 171/374 (45%), Gaps = 24/374 (6%)
Query: 552 RPEPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQL 611
RP + L+V R L+E +L S+ D K V F+ E+ +D GG +E+F+L
Sbjct: 460 RPHSKVTLKVSRHALLESSLKATRNFSIS---DWSKNFEVVFQDEEALDWGGPRREWFEL 516
Query: 612 IVEEIFNPDYGMFTHQQDSRNVWFNPTSFETE----AQFTLIGIVLGLAIYNNVI----- 662
I + +F+ +FT D+ +P + G ++G +Y + +
Sbjct: 517 ICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYK 576
Query: 663 --LAVNFPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQ 720
+ F +++G + ++ +P Y + +D+ E+ Y
Sbjct: 577 QLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFI--LNNDMSEMELVFAEEKYN 634
Query: 721 DVFGTNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESP 780
+ EL G VT NK +++L A + L V+ + F +G + E+
Sbjct: 635 KSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENL 694
Query: 781 LGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGG-YASDSKIVQDFWGIVHSLPLEDKRK 839
L A F E+E+L+CG+ + + GG + K+++ FW +V SL E+ +
Sbjct: 695 L-AIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELAR 753
Query: 840 LLQFTTGSDRVPVGG---LCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDR 896
LLQFTTGS ++P GG LC +IA P LPTAHTCFN L LP YD+ +++
Sbjct: 754 LLQFTTGSSQLPPGGFAALCPSFQIIA--APTHSTLPTAHTCFNQLCLPTYDSYEEVHRM 811
Query: 897 LLKAINYS-KGFGL 909
L AI+ +GFG+
Sbjct: 812 LQLAISEGCEGFGM 825
>AK126332-1|BAC86528.1| 343|Homo sapiens protein ( Homo sapiens
cDNA FLJ44359 fis, clone TRACH3007479, highly similar
to Homo sapiens Nedd-4-like ubiquitin-protein ligase
(WWP2). ).
Length = 343
Score = 124 bits (298), Expect = 2e-27
Identities = 74/249 (29%), Positives = 136/249 (54%), Gaps = 11/249 (4%)
Query: 557 LRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEI 616
+++ V R L ED+ + I + DL+++L + GE+G+D GG+++E+F L+ E+
Sbjct: 76 VKISVSRQTLFEDSF---QQIMNMKPYDLRRRLFIIMRGEEGLDYGGIAREWFFLLSHEV 132
Query: 617 FNPDYGMFTHQ-QDSRNVWFNPTSF---ETEAQFTLIGIVLGLAIYNNVILAVNFPMVVY 672
NP Y +F + +++ + NP S + F IG + +A+Y+ + F + Y
Sbjct: 133 LNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFY 192
Query: 673 RKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELK 732
+++L ++ + +DL +P YN + + E ++LEE + + I ++ G HELK
Sbjct: 193 KRMLNKRPTLKDLESIDPEFYNSIVWIKE---NNLEECGLELYFIQDMEILGKVTTHELK 249
Query: 733 VNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEM 792
G++I VT+ENK+E++ L D+ VE Q +AF GF V L +F +E+E+
Sbjct: 250 EGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWL-RYFDEKELEL 308
Query: 793 LVCGSKVFD 801
++CG + D
Sbjct: 309 MLCGMQEID 317
>BC032301-1|AAH32301.1| 1026|Homo sapiens Unknown (protein for
IMAGE:5167597) protein.
Length = 1026
Score = 123 bits (297), Expect = 2e-27
Identities = 92/312 (29%), Positives = 146/312 (46%), Gaps = 16/312 (5%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEG--EQGVDEGGVSKEFFQLIVEEI 616
+ +RRS ++ED L +S + + V G E G+D+ GV KEF + I++ +
Sbjct: 683 ITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRV 742
Query: 617 FNPDYGMFTHQQDSRNVWFNPTSF--ETEAQ-FTLIGIVLGLAIYNNVILAVNFPMVVYR 673
F+P +F ++ +PTS+ E Q F +G +LG A+Y +++ V F
Sbjct: 743 FDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLS 802
Query: 674 KLLGRKGS-FEDLVDWNPIL----YNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMF 728
+LLG S F VD P L Y L + Y GD + ++ +DV G +
Sbjct: 803 QLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLSYD---EDVMGQLVC 859
Query: 729 HELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPE 788
HEL G I VT ENK ++ L A F ++ ++ Q A GF + + F PE
Sbjct: 860 HELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPE 919
Query: 789 EVEMLVCGSKV-FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKL-LQFTTG 846
++ L+ G D +L+K T Y GG+ +++ W I+ S D+R + L+F T
Sbjct: 920 -LQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTS 978
Query: 847 SDRVPVGGLCNL 858
R P+ G L
Sbjct: 979 CSRPPLLGFAYL 990
>BX537403-1|CAD97645.1| 1068|Homo sapiens hypothetical protein
protein.
Length = 1068
Score = 122 bits (293), Expect = 8e-27
Identities = 91/312 (29%), Positives = 146/312 (46%), Gaps = 16/312 (5%)
Query: 559 LRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEG--EQGVDEGGVSKEFFQLIVEEI 616
+ +RRS ++ED L +S + + V G E G+D+ GV KEF + I++ +
Sbjct: 683 ITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRV 742
Query: 617 FNPDYGMFTHQQDSRNVWFNPTSF--ETEAQ-FTLIGIVLGLAIYNNVILAVNFPMVVYR 673
F+P +F ++ +PTS+ E Q F +G +LG A+Y +++ V F
Sbjct: 743 FDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLS 802
Query: 674 KLLGRKGS-FEDLVDWNPIL----YNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMF 728
+LLG S F VD P L Y L + Y GD + ++ +DV G +
Sbjct: 803 QLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLSYD---EDVMGQLVC 859
Query: 729 HELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPE 788
HEL G I VT ENK ++ L A F ++ ++ Q A GF + + F P
Sbjct: 860 HELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIVKPEWIRMFSTP- 918
Query: 789 EVEMLVCGSKV-FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKL-LQFTTG 846
E++ L+ G D +L+K T + GG+ +++ W I+ S D+R + L+F T
Sbjct: 919 ELQRLISGDNAEIDLEDLKKHTVHYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTS 978
Query: 847 SDRVPVGGLCNL 858
R P+ G L
Sbjct: 979 CSRPPLLGFAYL 990
Score = 46.4 bits (105), Expect = 5e-04
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Query: 852 VGGLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
+G + +F I + P RLPT+ TCFN+L LP Y + L+++L AI+ + GF L
Sbjct: 1011 LGSVLRGSFTIRKREPG-GRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFEL 1067
>AJ001112-1|CAA04539.1| 76|Homo sapiens E6-AP ubiquitin-protein
ligase protein.
Length = 76
Score = 113 bits (271), Expect = 4e-24
Identities = 49/76 (64%), Positives = 63/76 (82%)
Query: 747 EFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELE 806
EFV+LY+D++LN SVE QF+AFRRGF MVT+ESPL FRPEE+E+L+CGS+ DF LE
Sbjct: 1 EFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRNLDFQALE 60
Query: 807 KSTEYDGGYASDSKIV 822
++TEYDGGY DS ++
Sbjct: 61 ETTEYDGGYTRDSVLI 76
>D28476-1|BAA05837.2| 2005|Homo sapiens KIAA0045 protein.
Length = 2005
Score = 108 bits (259), Expect = 1e-22
Identities = 73/181 (40%), Positives = 100/181 (55%), Gaps = 12/181 (6%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
ELK G +I VT N +E++ L + LN V QF +FR GF V S L +F PEE
Sbjct: 1816 ELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHL-QYFYPEE 1874
Query: 790 VEMLVCGSKV--FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
++ L+CGSK +D L + D GY DS+ V+ + I+ S E +R LQF TGS
Sbjct: 1875 LDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGS 1934
Query: 848 DRVPVGGLCNLN--FVIAR------NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLK 899
R+PVGG +LN I R PD D LP+ TC N L LP+Y + + ++++LL
Sbjct: 1935 PRLPVGGFRSLNPPLTIVRKTFESTENPD-DFLPSVMTCVNYLKLPDYSSIEIMREKLLI 1993
Query: 900 A 900
A
Sbjct: 1994 A 1994
>BC114556-1|AAI14557.1| 2040|Homo sapiens TRIP12 protein protein.
Length = 2040
Score = 108 bits (259), Expect = 1e-22
Identities = 73/181 (40%), Positives = 100/181 (55%), Gaps = 12/181 (6%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
ELK G +I VT N +E++ L + LN V QF +FR GF V S L +F PEE
Sbjct: 1851 ELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHL-QYFYPEE 1909
Query: 790 VEMLVCGSKV--FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
++ L+CGSK +D L + D GY DS+ V+ + I+ S E +R LQF TGS
Sbjct: 1910 LDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGS 1969
Query: 848 DRVPVGGLCNLN--FVIAR------NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLK 899
R+PVGG +LN I R PD D LP+ TC N L LP+Y + + ++++LL
Sbjct: 1970 PRLPVGGFRSLNPPLTIVRKTFESTENPD-DFLPSVMTCVNYLKLPDYSSIEIMREKLLI 2028
Query: 900 A 900
A
Sbjct: 2029 A 2029
>BC113891-1|AAI13892.1| 1722|Homo sapiens TRIP12 protein protein.
Length = 1722
Score = 108 bits (259), Expect = 1e-22
Identities = 73/181 (40%), Positives = 100/181 (55%), Gaps = 12/181 (6%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
ELK G +I VT N +E++ L + LN V QF +FR GF V S L +F PEE
Sbjct: 1533 ELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHL-QYFYPEE 1591
Query: 790 VEMLVCGSKV--FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
++ L+CGSK +D L + D GY DS+ V+ + I+ S E +R LQF TGS
Sbjct: 1592 LDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGS 1651
Query: 848 DRVPVGGLCNLN--FVIAR------NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLK 899
R+PVGG +LN I R PD D LP+ TC N L LP+Y + + ++++LL
Sbjct: 1652 PRLPVGGFRSLNPPLTIVRKTFESTENPD-DFLPSVMTCVNYLKLPDYSSIEIMREKLLI 1710
Query: 900 A 900
A
Sbjct: 1711 A 1711
>AC093384-2|AAY14681.1| 1299|Homo sapiens unknown protein.
Length = 1299
Score = 108 bits (259), Expect = 1e-22
Identities = 73/181 (40%), Positives = 100/181 (55%), Gaps = 12/181 (6%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
ELK G +I VT N +E++ L + LN V QF +FR GF V S L +F PEE
Sbjct: 1110 ELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHL-QYFYPEE 1168
Query: 790 VEMLVCGSKV--FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
++ L+CGSK +D L + D GY DS+ V+ + I+ S E +R LQF TGS
Sbjct: 1169 LDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGS 1228
Query: 848 DRVPVGGLCNLN--FVIAR------NGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLK 899
R+PVGG +LN I R PD D LP+ TC N L LP+Y + + ++++LL
Sbjct: 1229 PRLPVGGFRSLNPPLTIVRKTFESTENPD-DFLPSVMTCVNYLKLPDYSSIEIMREKLLI 1287
Query: 900 A 900
A
Sbjct: 1288 A 1288
>AJ001110-1|CAA04537.1| 68|Homo sapiens E6-AP ubiquitin-protein
ligase protein.
Length = 68
Score = 107 bits (257), Expect = 2e-22
Identities = 48/68 (70%), Positives = 58/68 (85%)
Query: 623 MFTHQQDSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSF 682
MFT+ + ++ WFNP+SFETE QFTLIGIVLGLAIYNN IL V+FPMVVYRKL+G+KG+F
Sbjct: 1 MFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTF 60
Query: 683 EDLVDWNP 690
DL D +P
Sbjct: 61 RDLGDSHP 68
>BC063686-1|AAH63686.1| 347|Homo sapiens HECTD1 protein protein.
Length = 347
Score = 106 bits (255), Expect = 3e-22
Identities = 64/186 (34%), Positives = 102/186 (54%), Gaps = 7/186 (3%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
+LK +G++ +T +N +E+VDL DF ++ ++ Q AFR GF V L +F EE
Sbjct: 164 DLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSH-EE 222
Query: 790 VEMLVCG--SKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
V+M++CG S + ++ TE GY DS F ++ + ++++ LQFTTG
Sbjct: 223 VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGC 282
Query: 848 DRVPVGGLCNLN--FVIARNGPDCD-RLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYS 904
+P GGL NL+ + R D P+ +TC + L LPEY + + +++RLL A
Sbjct: 283 STLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLL-AATME 341
Query: 905 KGFGLH 910
KGF L+
Sbjct: 342 KGFHLN 347
>BC011658-1|AAH11658.2| 520|Homo sapiens HECTD1 protein protein.
Length = 520
Score = 106 bits (255), Expect = 3e-22
Identities = 64/186 (34%), Positives = 102/186 (54%), Gaps = 7/186 (3%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
+LK +G++ +T +N +E+VDL DF ++ ++ Q AFR GF V L +F EE
Sbjct: 337 DLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSH-EE 395
Query: 790 VEMLVCG--SKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
V+M++CG S + ++ TE GY DS F ++ + ++++ LQFTTG
Sbjct: 396 VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGC 455
Query: 848 DRVPVGGLCNLN--FVIARNGPDCD-RLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYS 904
+P GGL NL+ + R D P+ +TC + L LPEY + + +++RLL A
Sbjct: 456 STLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLL-AATME 514
Query: 905 KGFGLH 910
KGF L+
Sbjct: 515 KGFHLN 520
>AY739714-1|AAW65983.1| 1224|Homo sapiens HECTD1 protein.
Length = 1224
Score = 106 bits (255), Expect = 3e-22
Identities = 64/186 (34%), Positives = 102/186 (54%), Gaps = 7/186 (3%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
+LK +G++ +T +N +E+VDL DF ++ ++ Q AFR GF V L +F EE
Sbjct: 1041 DLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSH-EE 1099
Query: 790 VEMLVCG--SKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
V+M++CG S + ++ TE GY DS F ++ + ++++ LQFTTG
Sbjct: 1100 VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGC 1159
Query: 848 DRVPVGGLCNLN--FVIARNGPDCD-RLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYS 904
+P GGL NL+ + R D P+ +TC + L LPEY + + +++RLL A
Sbjct: 1160 STLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLL-AATME 1218
Query: 905 KGFGLH 910
KGF L+
Sbjct: 1219 KGFHLN 1224
>AY254380-1|AAP13073.1| 2612|Homo sapiens E3 ligase for inhibin
receptor protein.
Length = 2612
Score = 106 bits (255), Expect = 3e-22
Identities = 64/186 (34%), Positives = 102/186 (54%), Gaps = 7/186 (3%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
+LK +G++ +T +N +E+VDL DF ++ ++ Q AFR GF V L +F EE
Sbjct: 2429 DLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSH-EE 2487
Query: 790 VEMLVCG--SKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
V+M++CG S + ++ TE GY DS F ++ + ++++ LQFTTG
Sbjct: 2488 VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGC 2547
Query: 848 DRVPVGGLCNLN--FVIARNGPDCD-RLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYS 904
+P GGL NL+ + R D P+ +TC + L LPEY + + +++RLL A
Sbjct: 2548 STLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLL-AATME 2606
Query: 905 KGFGLH 910
KGF L+
Sbjct: 2607 KGFHLN 2612
>AL110222-1|CAB53681.1| 959|Homo sapiens hypothetical protein
protein.
Length = 959
Score = 106 bits (255), Expect = 3e-22
Identities = 64/186 (34%), Positives = 102/186 (54%), Gaps = 7/186 (3%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
+LK +G++ +T +N +E+VDL DF ++ ++ Q AFR GF V L +F EE
Sbjct: 776 DLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSH-EE 834
Query: 790 VEMLVCG--SKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
V+M++CG S + ++ TE GY DS F ++ + ++++ LQFTTG
Sbjct: 835 VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGC 894
Query: 848 DRVPVGGLCNLN--FVIARNGPDCD-RLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYS 904
+P GGL NL+ + R D P+ +TC + L LPEY + + +++RLL A
Sbjct: 895 STLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLL-AATME 953
Query: 905 KGFGLH 910
KGF L+
Sbjct: 954 KGFHLN 959
>AB032957-1|BAA86445.2| 2168|Homo sapiens KIAA1131 protein protein.
Length = 2168
Score = 106 bits (255), Expect = 3e-22
Identities = 64/186 (34%), Positives = 102/186 (54%), Gaps = 7/186 (3%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
+LK +G++ +T +N +E+VDL DF ++ ++ Q AFR GF V L +F EE
Sbjct: 1985 DLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSH-EE 2043
Query: 790 VEMLVCG--SKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
V+M++CG S + ++ TE GY DS F ++ + ++++ LQFTTG
Sbjct: 2044 VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGC 2103
Query: 848 DRVPVGGLCNLN--FVIARNGPDCD-RLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYS 904
+P GGL NL+ + R D P+ +TC + L LPEY + + +++RLL A
Sbjct: 2104 STLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLL-AATME 2162
Query: 905 KGFGLH 910
KGF L+
Sbjct: 2163 KGFHLN 2168
>L40383-1|AAC41731.1| 174|Homo sapiens thyroid receptor interactor
protein.
Length = 174
Score = 103 bits (246), Expect = 4e-21
Identities = 70/168 (41%), Positives = 91/168 (54%), Gaps = 12/168 (7%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
ELK G +I VT N +E++ L + LN V QF +FR GF V S L +F PEE
Sbjct: 3 ELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHL-QYFYPEE 61
Query: 790 VEMLVCGSKV--FDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGS 847
++ L+CGSK +D L + D GY DS+ V+ + I+ S E +R LQF TGS
Sbjct: 62 LDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGS 121
Query: 848 DRVPVGGLCNLN--FVIAR------NGPDCDRLPTAHTCFNVLLLPEY 887
R+PVGG +LN I R PD D LP+ TC N L LP+Y
Sbjct: 122 PRLPVGGFRSLNPPLTIVRKTFESTENPD-DFLPSVMTCVNYLKLPDY 168
>BC032944-1|AAH32944.1| 789|Homo sapiens KIAA0317 protein protein.
Length = 789
Score = 103 bits (246), Expect = 4e-21
Identities = 89/341 (26%), Positives = 150/341 (43%), Gaps = 23/341 (6%)
Query: 552 RPEPFLRLRVRRSHLIEDALVVLEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQL 611
RP + L+V R L+E +L S+ D K V F+ E+ +D GG +E+F+L
Sbjct: 457 RPHSKVTLKVSRHALLESSLKATRNFSIS---DWSKNFEVVFQDEEALDWGGPRREWFEL 513
Query: 612 IVEEIFNPDYGMFTHQQDSRNVWFNPTSFETE----AQFTLIGIVLGLAIYNNVI----- 662
I + +F+ +FT D+ +P + G ++G +Y + +
Sbjct: 514 ICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYK 573
Query: 663 --LAVNFPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYTGDDLEEVYYQTFRICYQ 720
+ F +++G + ++ +P Y + +D+ E+ Y
Sbjct: 574 QLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFI--LNNDMSEMELVFAEEKYN 631
Query: 721 DVFGTNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESP 780
+ EL G VT NK +++L A + L V+ + F +G + E+
Sbjct: 632 KSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENL 691
Query: 781 LGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGG-YASDSKIVQDFWGIVHSLPLEDKRK 839
L A F E+E+L+CG+ + + GG + K+++ FW +V SL E+ +
Sbjct: 692 L-AIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELAR 750
Query: 840 LLQFTTGSDRVPVGG---LCNLNFVIARNGPDCDRLPTAHT 877
LLQFTTGS ++P GG LC +IA P LPTAHT
Sbjct: 751 LLQFTTGSSQLPPGGFAALCPSFQIIA--APTHSTLPTAHT 789
>U95000-1|AAF88143.1| 2798|Homo sapiens hyd protein protein.
Length = 2798
Score = 100 bits (240), Expect = 2e-20
Identities = 87/298 (29%), Positives = 139/298 (46%), Gaps = 21/298 (7%)
Query: 626 HQQDSRNVWFNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSF 682
+Q R + TEA+ F IG +LGL + N + + V + LLGRK ++
Sbjct: 2505 YQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNW 2564
Query: 683 EDLVDWNPILYNGLKDM-LEYTGDDLEEVYYQ-----TFRICYQDVFGTNMFHELKVNGD 736
D ++P++Y L+ + L D + V+ +C ++ G EL NG
Sbjct: 2565 HDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQ---VELIPNGV 2621
Query: 737 NIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCG 796
NI VT +N E+V YA+ + V E A R+G L V ++ L E+ +LV G
Sbjct: 2622 NIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSL-EDLTAEDFRLLVNG 2680
Query: 797 SKVFDFHELEKSTEY-DGGYASDSKIVQD---FWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
+ L T + D + K++Q FW IV + + +++ L+ F T S +P
Sbjct: 2681 CGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPA 2740
Query: 853 G--GLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFG 908
G + + R PD LPTA+TC + L +P Y ++ L+ +LL AI +K FG
Sbjct: 2741 SEEGFQPMPSITIR-PPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIK-TKNFG 2796
>AF006010-1|AAD01259.2| 2799|Homo sapiens progestin induced protein
protein.
Length = 2799
Score = 100 bits (240), Expect = 2e-20
Identities = 87/298 (29%), Positives = 139/298 (46%), Gaps = 21/298 (7%)
Query: 626 HQQDSRNVWFNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSF 682
+Q R + TEA+ F IG +LGL + N + + V + LLGRK ++
Sbjct: 2506 YQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNW 2565
Query: 683 EDLVDWNPILYNGLKDM-LEYTGDDLEEVYYQ-----TFRICYQDVFGTNMFHELKVNGD 736
D ++P++Y L+ + L D + V+ +C ++ G EL NG
Sbjct: 2566 HDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQ---VELIPNGV 2622
Query: 737 NIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCG 796
NI VT +N E+V YA+ + V E A R+G L V ++ L E+ +LV G
Sbjct: 2623 NIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSL-EDLTAEDFRLLVNG 2681
Query: 797 SKVFDFHELEKSTEY-DGGYASDSKIVQD---FWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
+ L T + D + K++Q FW IV + + +++ L+ F T S +P
Sbjct: 2682 CGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPA 2741
Query: 853 G--GLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFG 908
G + + R PD LPTA+TC + L +P Y ++ L+ +LL AI +K FG
Sbjct: 2742 SEEGFQPMPSITIR-PPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIK-TKNFG 2797
>AB020703-1|BAA74919.3| 2820|Homo sapiens KIAA0896 protein protein.
Length = 2820
Score = 100 bits (240), Expect = 2e-20
Identities = 87/298 (29%), Positives = 139/298 (46%), Gaps = 21/298 (7%)
Query: 626 HQQDSRNVWFNPTSFETEAQ---FTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSF 682
+Q R + TEA+ F IG +LGL + N + + V + LLGRK ++
Sbjct: 2527 YQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNW 2586
Query: 683 EDLVDWNPILYNGLKDM-LEYTGDDLEEVYYQ-----TFRICYQDVFGTNMFHELKVNGD 736
D ++P++Y L+ + L D + V+ +C ++ G EL NG
Sbjct: 2587 HDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQ---VELIPNGV 2643
Query: 737 NIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCG 796
NI VT +N E+V YA+ + V E A R+G L V ++ L E+ +LV G
Sbjct: 2644 NIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSL-EDLTAEDFRLLVNG 2702
Query: 797 SKVFDFHELEKSTEY-DGGYASDSKIVQD---FWGIVHSLPLEDKRKLLQFTTGSDRVPV 852
+ L T + D + K++Q FW IV + + +++ L+ F T S +P
Sbjct: 2703 CGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPA 2762
Query: 853 G--GLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFG 908
G + + R PD LPTA+TC + L +P Y ++ L+ +LL AI +K FG
Sbjct: 2763 SEEGFQPMPSITIR-PPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIK-TKNFG 2818
>AL834183-1|CAD38880.1| 523|Homo sapiens hypothetical protein
protein.
Length = 523
Score = 92.3 bits (219), Expect = 7e-18
Identities = 71/267 (26%), Positives = 125/267 (46%), Gaps = 13/267 (4%)
Query: 644 AQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYT 703
+ F +G++LG+AI L++N V+++L G + DL + + GL + +
Sbjct: 220 SMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNE 279
Query: 704 GDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVET 763
EE + G +++++ + +T +N+ E+V L ++ L+ +
Sbjct: 280 ATS-EEFEAMSLPFTVPSASG----QDIQLSSKHTHITLDNRAEYVRLAINYRLH-EFDE 333
Query: 764 QFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQ 823
Q A R G V PL + F E+E +VCGS H L+ Y G S S ++Q
Sbjct: 334 QVAAVREGMARVVPV-PLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSAS-LIQ 391
Query: 824 DFWGIVHSLPLEDKRKLLQFTTGSDRVP--VGGLCNLNFVIA---RNGPDCDRLPTAHTC 878
FW ++ S ++ L+F G R+P + +FVI + P LP ++TC
Sbjct: 392 WFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTC 451
Query: 879 FNVLLLPEYDTRDKLQDRLLKAINYSK 905
F +L LP Y + L+++L AI++ K
Sbjct: 452 FFLLKLPRYSCKQVLEEKLKYAIHFCK 478
>AF225409-1|AAO27484.1| 306|Homo sapiens HERC2 protein.
Length = 306
Score = 92.3 bits (219), Expect = 7e-18
Identities = 71/267 (26%), Positives = 125/267 (46%), Gaps = 13/267 (4%)
Query: 644 AQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYT 703
+ F +G++LG+AI L++N V+++L G + DL + + GL + +
Sbjct: 3 SMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNE 62
Query: 704 GDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVET 763
EE + G +++++ + +T +N+ E+V L ++ L+ +
Sbjct: 63 ATS-EEFEAMSLPFTVPSASG----QDIQLSSKHTHITLDNRAEYVRLAINYRLH-EFDE 116
Query: 764 QFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQ 823
Q A R G V PL + F E+E +VCGS H L+ Y G S S ++Q
Sbjct: 117 QVAAVREGMARVVPV-PLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSAS-LIQ 174
Query: 824 DFWGIVHSLPLEDKRKLLQFTTGSDRVP--VGGLCNLNFVIA---RNGPDCDRLPTAHTC 878
FW ++ S ++ L+F G R+P + +FVI + P LP ++TC
Sbjct: 175 WFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTC 234
Query: 879 FNVLLLPEYDTRDKLQDRLLKAINYSK 905
F +L LP Y + L+++L AI++ K
Sbjct: 235 FFLLKLPRYSCKQVLEEKLKYAIHFCK 261
>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
Length = 4834
Score = 92.3 bits (219), Expect = 7e-18
Identities = 71/267 (26%), Positives = 125/267 (46%), Gaps = 13/267 (4%)
Query: 644 AQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPILYNGLKDMLEYT 703
+ F +G++LG+AI L++N V+++L G + DL + + GL + +
Sbjct: 4531 SMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNE 4590
Query: 704 GDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVET 763
EE + G +++++ + +T +N+ E+V L ++ L+ +
Sbjct: 4591 ATS-EEFEAMSLPFTVPSASG----QDIQLSSKHTHITLDNRAEYVRLAINYRLH-EFDE 4644
Query: 764 QFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQ 823
Q A R G V PL + F E+E +VCGS H L+ Y G S S ++Q
Sbjct: 4645 QVAAVREGMARVVPV-PLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSAS-LIQ 4702
Query: 824 DFWGIVHSLPLEDKRKLLQFTTGSDRVP--VGGLCNLNFVIA---RNGPDCDRLPTAHTC 878
FW ++ S ++ L+F G R+P + +FVI + P LP ++TC
Sbjct: 4703 WFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTC 4762
Query: 879 FNVLLLPEYDTRDKLQDRLLKAINYSK 905
F +L LP Y + L+++L AI++ K
Sbjct: 4763 FFLLKLPRYSCKQVLEEKLKYAIHFCK 4789
>AJ001109-1|CAA04536.1| 48|Homo sapiens E6-AP ubiquitin-protein
ligase protein.
Length = 48
Score = 88.2 bits (209), Expect = 1e-16
Identities = 41/47 (87%), Positives = 43/47 (91%)
Query: 574 LEMISMERALDLKKQLVVEFEGEQGVDEGGVSKEFFQLIVEEIFNPD 620
LEMI+ME DLKKQL VEFEGEQGVDEGGVSKEFFQL+VEEIFNPD
Sbjct: 1 LEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPD 47
>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
Length = 4861
Score = 86.6 bits (205), Expect = 4e-16
Identities = 69/273 (25%), Positives = 127/273 (46%), Gaps = 8/273 (2%)
Query: 635 FNPTSFETE--AQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPIL 692
FNP++ E QF +GI++G+AI L ++ +V+++L + EDL + + +
Sbjct: 4566 FNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLY 4625
Query: 693 YNGLKDMLEYTGDDL-EEVYYQTFRI-CYQDVFGTNMFHELKVNGDNIFVTQENKKEFVD 750
L +L + EE +++ + + + G++I +T N+KE+V+
Sbjct: 4626 VQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVE 4685
Query: 751 LYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTE 810
++ L+ ++ Q A R G + PL + +++E +VCG L+K
Sbjct: 4686 RAIEYRLH-EMDRQVAAVREGMSWIVPV-PLLSLLTAKQLEQMVCGMPEISVEVLKKVVR 4743
Query: 811 YDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGL-CNLNFVIARNGPDC 869
Y ++VQ FW + E++ ++F +G R+P + F I +
Sbjct: 4744 YRE-VDEQHQLVQWFWHTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPY 4802
Query: 870 DRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAIN 902
D LPT+ TCF L LP Y ++ + +RL AIN
Sbjct: 4803 DSLPTSQTCFFQLRLPPYSSQLVMAERLRYAIN 4835
>BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein.
Length = 651
Score = 86.6 bits (205), Expect = 4e-16
Identities = 69/273 (25%), Positives = 127/273 (46%), Gaps = 8/273 (2%)
Query: 635 FNPTSFETE--AQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDWNPIL 692
FNP++ E QF +GI++G+AI L ++ +V+++L + EDL + + +
Sbjct: 356 FNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLY 415
Query: 693 YNGLKDMLEYTGDDL-EEVYYQTFRI-CYQDVFGTNMFHELKVNGDNIFVTQENKKEFVD 750
L +L + EE +++ + + + G++I +T N+KE+V+
Sbjct: 416 VQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVE 475
Query: 751 LYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTE 810
++ L+ ++ Q A R G + PL + +++E +VCG L+K
Sbjct: 476 RAIEYRLH-EMDRQVAAVREGMSWIVPV-PLLSLLTAKQLEQMVCGMPEISVEVLKKVVR 533
Query: 811 YDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGL-CNLNFVIARNGPDC 869
Y ++VQ FW + E++ ++F +G R+P + F I +
Sbjct: 534 YRE-VDEQHQLVQWFWHTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPY 592
Query: 870 DRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAIN 902
D LPT+ TCF L LP Y ++ + +RL AIN
Sbjct: 593 DSLPTSQTCFFQLRLPPYSSQLVMAERLRYAIN 625
>BC083494-1|AAH83494.1| 171|Homo sapiens HECTD1 protein protein.
Length = 171
Score = 83.4 bits (197), Expect = 3e-15
Identities = 55/159 (34%), Positives = 83/159 (52%), Gaps = 7/159 (4%)
Query: 757 LNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCG--SKVFDFHELEKSTEYDGG 814
LN ++ Q AFR GF V L +F EEV+M++CG S + ++ TE G
Sbjct: 15 LNTRMQKQMEAFRDGFNKVFPMEKLSSFSH-EEVQMILCGNQSPSWAAEDIINYTEPKLG 73
Query: 815 YASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLN--FVIARNGPDCD-R 871
Y DS F ++ + ++++ LQFTTG +P GGL NL+ + R D
Sbjct: 74 YTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDAS 133
Query: 872 LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGLH 910
P+ +TC + L LPEY + + +++RLL A KGF L+
Sbjct: 134 YPSVNTCVHYLKLPEYSSEEIMRERLL-AATMEKGFHLN 171
>BC130470-1|AAI30471.1| 577|Homo sapiens HECT domain containing 3
protein.
Length = 577
Score = 78.2 bits (184), Expect = 1e-13
Identities = 72/272 (26%), Positives = 124/272 (45%), Gaps = 13/272 (4%)
Query: 629 DSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDW 688
++R+++ S A++ IG ++G A+ L + P V+++L G + S+ D+
Sbjct: 297 EARDMYVPNPSCRDFAKYEWIGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSK--DF 354
Query: 689 NPILYNGLKDMLEYT-GDDLEEVYYQTFR-ICYQDVFGTNMFHELKVNGDNIFVTQENKK 746
P + + L +LE G D E ++ + + + V EL G I V ++
Sbjct: 355 -PAVDSVLVKLLEVMEGMDKETFEFKFGKELTFTTVLSDQQVVELIPGGAGIVVGYGDRS 413
Query: 747 EFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELE 806
F+ L L S E Q A + G L V ++ L +E+E VCG L
Sbjct: 414 RFIQLVQKARLEESKE-QVAAMQAGLLKVVPQAVLD-LLTWQELEKKVCGDPEVTVDALR 471
Query: 807 KSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVIARNG 866
K T ++ SDS+ VQ FW +++ ED+ + L+F TG R+P + + G
Sbjct: 472 KLTRFEDFEPSDSR-VQYFWEALNNFTNEDRSRFLRFVTGRSRLP----ARIYIYPDKLG 526
Query: 867 PD-CDRLPTAHTCFNVLLLPEYDTRDKLQDRL 897
+ D LP + TC + L LP Y + +++L
Sbjct: 527 YETTDALPESSTCSSTLFLPHYASAKVCEEKL 558
>BC126352-1|AAI26353.1| 577|Homo sapiens HECT domain containing 3
protein.
Length = 577
Score = 78.2 bits (184), Expect = 1e-13
Identities = 72/272 (26%), Positives = 124/272 (45%), Gaps = 13/272 (4%)
Query: 629 DSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDW 688
++R+++ S A++ IG ++G A+ L + P V+++L G + S+ D+
Sbjct: 297 EARDMYVPNPSCRDFAKYEWIGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSK--DF 354
Query: 689 NPILYNGLKDMLEYT-GDDLEEVYYQTFR-ICYQDVFGTNMFHELKVNGDNIFVTQENKK 746
P + + L +LE G D E ++ + + + V EL G I V ++
Sbjct: 355 -PAVDSVLVKLLEVMEGMDKETFEFKFGKELTFTTVLSDQQVVELIPGGAGIVVGYGDRS 413
Query: 747 EFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELE 806
F+ L L S E Q A + G L V ++ L +E+E VCG L
Sbjct: 414 RFIQLVQKARLEESKE-QVAAMQAGLLKVVPQAVLD-LLTWQELEKKVCGDPEVTVDALR 471
Query: 807 KSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVIARNG 866
K T ++ SDS+ VQ FW +++ ED+ + L+F TG R+P + + G
Sbjct: 472 KLTRFEDFEPSDSR-VQYFWEALNNFTNEDRSRFLRFVTGRSRLP----ARIYIYPDKLG 526
Query: 867 PD-CDRLPTAHTCFNVLLLPEYDTRDKLQDRL 897
+ D LP + TC + L LP Y + +++L
Sbjct: 527 YETTDALPESSTCSSTLFLPHYASAKVCEEKL 558
>AL359473-2|CAI16438.1| 861|Homo sapiens HECT domain containing 3
protein.
Length = 861
Score = 78.2 bits (184), Expect = 1e-13
Identities = 72/272 (26%), Positives = 124/272 (45%), Gaps = 13/272 (4%)
Query: 629 DSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDW 688
++R+++ S A++ IG ++G A+ L + P V+++L G + S+ D+
Sbjct: 581 EARDMYVPNPSCRDFAKYEWIGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSK--DF 638
Query: 689 NPILYNGLKDMLEYT-GDDLEEVYYQTFR-ICYQDVFGTNMFHELKVNGDNIFVTQENKK 746
P + + L +LE G D E ++ + + + V EL G I V ++
Sbjct: 639 -PAVDSVLVKLLEVMEGMDKETFEFKFGKELTFTTVLSDQQVVELIPGGAGIVVGYGDRS 697
Query: 747 EFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELE 806
F+ L L S E Q A + G L V ++ L +E+E VCG L
Sbjct: 698 RFIQLVQKARLEESKE-QVAAMQAGLLKVVPQAVLD-LLTWQELEKKVCGDPEVTVDALR 755
Query: 807 KSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVIARNG 866
K T ++ SDS+ VQ FW +++ ED+ + L+F TG R+P + + G
Sbjct: 756 KLTRFEDFEPSDSR-VQYFWEALNNFTNEDRSRFLRFVTGRSRLP----ARIYIYPDKLG 810
Query: 867 PD-CDRLPTAHTCFNVLLLPEYDTRDKLQDRL 897
+ D LP + TC + L LP Y + +++L
Sbjct: 811 YETTDALPESSTCSSTLFLPHYASAKVCEEKL 842
>AL359473-1|CAI16437.1| 471|Homo sapiens HECT domain containing 3
protein.
Length = 471
Score = 78.2 bits (184), Expect = 1e-13
Identities = 72/272 (26%), Positives = 124/272 (45%), Gaps = 13/272 (4%)
Query: 629 DSRNVWFNPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFEDLVDW 688
++R+++ S A++ IG ++G A+ L + P V+++L G + S+ D+
Sbjct: 191 EARDMYVPNPSCRDFAKYEWIGQLMGAALRGKEFLVLALPGFVWKQLSGEEVSWSK--DF 248
Query: 689 NPILYNGLKDMLEYT-GDDLEEVYYQTFR-ICYQDVFGTNMFHELKVNGDNIFVTQENKK 746
P + + L +LE G D E ++ + + + V EL G I V ++
Sbjct: 249 -PAVDSVLVKLLEVMEGMDKETFEFKFGKELTFTTVLSDQQVVELIPGGAGIVVGYGDRS 307
Query: 747 EFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGSKVFDFHELE 806
F+ L L S E Q A + G L V ++ L +E+E VCG L
Sbjct: 308 RFIQLVQKARLEESKE-QVAAMQAGLLKVVPQAVLD-LLTWQELEKKVCGDPEVTVDALR 365
Query: 807 KSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLNFVIARNG 866
K T ++ SDS+ VQ FW +++ ED+ + L+F TG R+P + + G
Sbjct: 366 KLTRFEDFEPSDSR-VQYFWEALNNFTNEDRSRFLRFVTGRSRLP----ARIYIYPDKLG 420
Query: 867 PD-CDRLPTAHTCFNVLLLPEYDTRDKLQDRL 897
+ D LP + TC + L LP Y + +++L
Sbjct: 421 YETTDALPESSTCSSTLFLPHYASAKVCEEKL 452
>BC006848-1|AAH06848.1| 118|Homo sapiens Similar to RIKEN cDNA
1300010O06 gene protein.
Length = 118
Score = 75.4 bits (177), Expect = 9e-13
Identities = 42/101 (41%), Positives = 61/101 (60%), Gaps = 8/101 (7%)
Query: 815 YASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNL-------NFVIARNGP 867
YA SK + FW V + E + +LLQF TG+ R+PVGG +L F I + G
Sbjct: 17 YARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGK 76
Query: 868 DCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFG 908
+ + LP +HTCFN L LP Y + ++L+++LL AI ++GFG
Sbjct: 77 E-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFG 116
>AJ001113-1|CAA04540.1| 39|Homo sapiens E6-AP ubiquitin-protein
ligase protein.
Length = 39
Score = 69.3 bits (162), Expect = 6e-11
Identities = 28/38 (73%), Positives = 36/38 (94%)
Query: 872 LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
LPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 1 LPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 38
>AF009341-1|AAC39580.1| 39|Homo sapiens E6-AP ubiquitin-protein
ligase protein.
Length = 39
Score = 69.3 bits (162), Expect = 6e-11
Identities = 28/38 (73%), Positives = 36/38 (94%)
Query: 872 LPTAHTCFNVLLLPEYDTRDKLQDRLLKAINYSKGFGL 909
LPT+HTCFNVLLLPEY +++KL++RLLKAI Y+KGFG+
Sbjct: 1 LPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGM 38
>AJ001107-1|CAA04534.1| 99|Homo sapiens E6-AP ubiquitin-protein
ligase protein.
Length = 99
Score = 68.1 bits (159), Expect = 1e-10
Identities = 39/97 (40%), Positives = 58/97 (59%), Gaps = 6/97 (6%)
Query: 39 KRAAAKQLIEKYFYQLLDGCGNVNCDNRYCASSGAARNLSPNEAAAEAIKLFYKEARLCS 98
KRAAAK LIE+Y++QL +GCGN C N +CAS + N AA +A++L+ A+LC
Sbjct: 1 KRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLCD 60
Query: 99 SVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQ 135
P+ + S++Y +S PN+ + SE K N+
Sbjct: 61 ---PHPSKKGASSAY--LENSKGAPNN-SCSEIKMNK 91
>BC019105-1|AAH19105.1| 210|Homo sapiens HECTD3 protein protein.
Length = 210
Score = 64.9 bits (151), Expect = 1e-09
Identities = 51/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)
Query: 717 ICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVT 776
+ + V EL G I V ++ F+ L L S E Q A + G L V
Sbjct: 17 LTFTTVLSDQQVVELIPGGAGIVVGYGDRSRFIQLVQKARLEESKE-QVAAMQAGLLKVV 75
Query: 777 DESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLED 836
++ L +E+E VCG L K T ++ SDS+ VQ FW +++ ED
Sbjct: 76 PQAVLD-LLTWQELEKKVCGDPEVTVDALRKLTRFEDFEPSDSR-VQYFWEALNNFTNED 133
Query: 837 KRKLLQFTTGSDRVPVGGLCNLNFVIARNGPD-CDRLPTAHTCFNVLLLPEYDTRDKLQD 895
+ + L+F TG R+P + + G + D LP + TC + L LP Y + ++
Sbjct: 134 RSRFLRFVTGRSRLP----ARIYIYPDKLGYETTDALPESSTCSSTLFLPHYASAKVCEE 189
Query: 896 RL 897
+L
Sbjct: 190 KL 191
>AK024809-1|BAB15015.1| 210|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21156 fis, clone CAS09878. ).
Length = 210
Score = 64.9 bits (151), Expect = 1e-09
Identities = 51/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)
Query: 717 ICYQDVFGTNMFHELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVT 776
+ + V EL G I V ++ F+ L L S E Q A + G L V
Sbjct: 17 LTFTTVLSDQQVVELIPGGAGIVVGYGDRSRFIQLVQKARLEESKE-QVAAMQAGLLKVV 75
Query: 777 DESPLGAFFRPEEVEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLED 836
++ L +E+E VCG L K T ++ SDS+ VQ FW +++ ED
Sbjct: 76 PQAVLD-LLTWQELEKKVCGDPEVTVDALRKLTRFEDFEPSDSR-VQYFWEALNNFTNED 133
Query: 837 KRKLLQFTTGSDRVPVGGLCNLNFVIARNGPD-CDRLPTAHTCFNVLLLPEYDTRDKLQD 895
+ + L+F TG R+P + + G + D LP + TC + L LP Y + ++
Sbjct: 134 RSRFLRFVTGRSRLP----ARIYIYPDKLGYETTDALPESSTCSSTLFLPHYASAKVCEE 189
Query: 896 RL 897
+L
Sbjct: 190 KL 191
>AJ001111-1|CAA04538.1| 55|Homo sapiens E6-AP ubiquitin-protein
ligase protein.
Length = 55
Score = 57.2 bits (132), Expect = 2e-07
Identities = 27/56 (48%), Positives = 38/56 (67%), Gaps = 1/56 (1%)
Query: 691 ILYNGLKDMLEYTGDDLEEVYYQTFRICYQDVFGTNMFHELKVNGDNIFVTQENKK 746
+LY LKD+LEY G+ +E+ TF+I D+FG M ++LK NGD I +T EN+K
Sbjct: 1 VLYQSLKDLLEYEGN-VEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNENRK 55
>BC006237-1|AAH06237.2| 121|Homo sapiens HECTD1 protein protein.
Length = 121
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Query: 825 FWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCNLN--FVIARNGPDCD-RLPTAHTCFNV 881
F ++ + ++++ LQFTTG +P GGL NL+ + R D P+ +TC +
Sbjct: 34 FVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHY 93
Query: 882 LLLPEYDTRDKLQDRLLKAINYSKGFGLH 910
L LPEY + + +++RLL A KGF L+
Sbjct: 94 LKLPEYSSEEIMRERLL-AATMEKGFHLN 121
>AF174498-1|AAF36539.1| 1381|Homo sapiens GR AF-1 specific protein
phosphatase protein.
Length = 1381
Score = 44.8 bits (101), Expect = 0.001
Identities = 67/302 (22%), Positives = 116/302 (38%), Gaps = 36/302 (11%)
Query: 636 NPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFE-DLVDWNPILYN 694
+P ++ E +G +LG+AI +V L ++ ++ L+G E DL + + + YN
Sbjct: 1075 SPITYGEEQLLHFLGQLLGIAIRADVPLPLDLLPSFWKTLVGDALDPEQDLQEADILTYN 1134
Query: 695 GLKDMLEYTGDDLE------EVYYQTF---------RICYQDVFGTNMFHELKV--NGDN 737
+K E D+ E E+ Q + C + + T E+++ G +
Sbjct: 1135 YVKKF-ESINDETELEALCAEIASQHLATESPDSPNKPCCRFTYLTMTGREVELCSRGRH 1193
Query: 738 IFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGS 797
I V ENK + L + R L L P E+E+ CG
Sbjct: 1194 ILVAWENKDIYAAAIRSLRLRALQNVECVTAVRAGLGSIIPLQLLTMLSPLEMELRTCGL 1253
Query: 798 KVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCN 857
+ L+ T Y G + ++ FWG + E+ K ++F +R+P C
Sbjct: 1254 PYINLEFLKAHTMYQVGLMETDQHIEFFWGALEMFTQEELCKFIKFACNQERIPFTCPCK 1313
Query: 858 -----------LNFVIA-----RNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI 901
IA PD R TC ++ LP+Y + + + ++L AI
Sbjct: 1314 DGGPDTAHVPPYPMKIAPPDGTAGSPD-SRYIRVETCMFMIKLPQYSSLEIMLEKLRGAI 1372
Query: 902 NY 903
+Y
Sbjct: 1373 HY 1374
>BC021144-1|AAH21144.1| 740|Homo sapiens FLJ30092 protein protein.
Length = 740
Score = 44.4 bits (100), Expect = 0.002
Identities = 67/302 (22%), Positives = 116/302 (38%), Gaps = 36/302 (11%)
Query: 636 NPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFE-DLVDWNPILYN 694
+P ++ E +G +LG+AI +V L ++ ++ L+G E DL + + + YN
Sbjct: 434 SPITYGEEQLLHFLGQLLGIAIRADVPLPLDLLPSFWKTLVGEPLDPEQDLQEADILTYN 493
Query: 695 GLKDMLEYTGDDLE------EVYYQTF---------RICYQDVFGTNMFHELKV--NGDN 737
+K E D+ E E+ Q + C + + T E+++ G +
Sbjct: 494 YVKKF-ESINDETELEALCAEIASQHLATESPDSPNKPCCRFTYLTMTGEEVELCSRGRH 552
Query: 738 IFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGS 797
I V ENK + L + R L L P E+E+ CG
Sbjct: 553 ILVAWENKDIYAAAIRSLRLRELQNVECVTAVRAGLGSIIPLQLLTMLSPLEMELRTCGL 612
Query: 798 KVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCN 857
+ L+ T Y G + ++ FWG + E+ K ++F +R+P C
Sbjct: 613 PYINLEFLKAHTMYQVGLMETDQHIEFFWGALEMFTQEELCKFIKFACNQERIPFTCPCK 672
Query: 858 -----------LNFVIA-----RNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI 901
IA PD R TC ++ LP+Y + + + ++L AI
Sbjct: 673 DGGPDTAHVPPYPMKIAPPDGTAGSPD-SRYIRVETCMFMIKLPQYSSLEIMLEKLRCAI 731
Query: 902 NY 903
+Y
Sbjct: 732 HY 733
>AB014514-1|BAA31589.3| 3006|Homo sapiens KIAA0614 protein protein.
Length = 3006
Score = 44.4 bits (100), Expect = 0.002
Identities = 67/302 (22%), Positives = 116/302 (38%), Gaps = 36/302 (11%)
Query: 636 NPTSFETEAQFTLIGIVLGLAIYNNVILAVNFPMVVYRKLLGRKGSFE-DLVDWNPILYN 694
+P ++ E +G +LG+AI +V L ++ ++ L+G E DL + + + YN
Sbjct: 2700 SPITYGEEQLLHFLGQLLGIAIRADVPLPLDLLPSFWKTLVGEPLDPEQDLQEADILTYN 2759
Query: 695 GLKDMLEYTGDDLE------EVYYQTF---------RICYQDVFGTNMFHELKV--NGDN 737
+K E D+ E E+ Q + C + + T E+++ G +
Sbjct: 2760 YVKKF-ESINDETELEALCAEIASQHLATESPDSPNKPCCRFTYLTMTGEEVELCSRGRH 2818
Query: 738 IFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEEVEMLVCGS 797
I V ENK + L + R L L P E+E+ CG
Sbjct: 2819 ILVAWENKDIYAAAIRSLRLRELQNVECVTAVRAGLGSIIPLQLLTMLSPLEMELRTCGL 2878
Query: 798 KVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDRVPVGGLCN 857
+ L+ T Y G + ++ FWG + E+ K ++F +R+P C
Sbjct: 2879 PYINLEFLKAHTMYQVGLMETDQHIEFFWGALEMFTQEELCKFIKFACNQERIPFTCPCK 2938
Query: 858 -----------LNFVIA-----RNGPDCDRLPTAHTCFNVLLLPEYDTRDKLQDRLLKAI 901
IA PD R TC ++ LP+Y + + + ++L AI
Sbjct: 2939 DGGPDTAHVPPYPMKIAPPDGTAGSPD-SRYIRVETCMFMIKLPQYSSLEIMLEKLRCAI 2997
Query: 902 NY 903
+Y
Sbjct: 2998 HY 2999
>BC006270-1|AAH06270.2| 274|Homo sapiens FLJ30092 protein protein.
Length = 274
Score = 42.7 bits (96), Expect = 0.006
Identities = 44/190 (23%), Positives = 69/190 (36%), Gaps = 17/190 (8%)
Query: 730 ELKVNGDNIFVTQENKKEFVDLYADFLLNVSVETQFRAFRRGFLMVTDESPLGAFFRPEE 789
EL G +I V ENK + L + R L L P E
Sbjct: 79 ELCSRGRHILVAWENKDIYAAAIRSLRLRELQNVECVTAVRAGLGSIIPLQLLTMLSPLE 138
Query: 790 VEMLVCGSKVFDFHELEKSTEYDGGYASDSKIVQDFWGIVHSLPLEDKRKLLQFTTGSDR 849
+E+ CG + L+ T Y G + ++ FWG + E+ K ++F +R
Sbjct: 139 MELRTCGLPYINLEFLKAHTMYQVGLMETDQHIEFFWGALEMFTQEELCKFIKFACNQER 198
Query: 850 VPVGGLCN-----------LNFVIA-----RNGPDCDRLPTAHTCFNVLLLPEYDTRDKL 893
+P C IA PD R TC ++ LP+Y + + +
Sbjct: 199 IPFTCPCKDGGPDTAHVPPYPMKIAPPDGTAGSPD-SRYIRVETCMFMIKLPQYSSLEIM 257
Query: 894 QDRLLKAINY 903
++L AI+Y
Sbjct: 258 LEKLRCAIHY 267
>BC044598-1|AAH44598.1| 79|Homo sapiens EDD1 protein protein.
Length = 79
Score = 41.9 bits (94), Expect = 0.010
Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Query: 832 LPLEDKRKLLQFTTGSDRVPVG--GLCNLNFVIARNGPDCDRLPTAHTCFNVLLLPEYDT 889
+ + +++ L+ F T S +P G + + R PD LPTA+TC + L +P Y +
Sbjct: 1 MSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRP-PDDQHLPTANTCISRLYVPLYSS 59
Query: 890 RDKLQDRLLKAINYSKGFG 908
+ L+ +LL AI +K FG
Sbjct: 60 KQILKQKLLLAIK-TKNFG 77
>X54890-1|CAA38662.1| 793|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 793
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>X54130-1|CAA38065.1| 793|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 793
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>X53364-1|CAA37447.1| 793|Homo sapiens tyrosine phosphatase
precursor protein.
Length = 793
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>M34668-1|AAA36528.1| 802|Homo sapiens protein ( Human protein
tyrosine phosphatase (PTPase-alpha) mRNA. ).
Length = 802
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>BC027308-1|AAH27308.1| 793|Homo sapiens protein tyrosine
phosphatase, receptor type, A protein.
Length = 793
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>AL121905-6|CAC10336.1| 802|Homo sapiens protein tyrosine
phosphatase, receptor type, A protein.
Length = 802
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>AL121905-5|CAC10337.1| 793|Homo sapiens protein tyrosine
phosphatase, receptor type, A protein.
Length = 793
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>AL121905-4|CAI21711.1| 253|Homo sapiens protein tyrosine
phosphatase, receptor type, A protein.
Length = 253
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>AL121905-3|CAI21710.1| 200|Homo sapiens protein tyrosine
phosphatase, receptor type, A protein.
Length = 200
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>AL121905-2|CAI21709.1| 175|Homo sapiens protein tyrosine
phosphatase, receptor type, A protein.
Length = 175
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>AL121905-1|CAI21708.1| 138|Homo sapiens protein tyrosine
phosphatase, receptor type, A protein.
Length = 138
Score = 36.3 bits (80), Expect = 0.49
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 68 CASSGAARNLSPNEAAAEAIKLFYKEARLCSSVTPNKVSRTDSNSYEP--SPSSTLGPNH 125
C S+ A ++P+ I E + T N S S S P SP+ TLGP +
Sbjct: 16 CVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTY 75
Query: 126 KNTSENKENQNITTPEPSTASRG 148
T + ++ N TT ST S G
Sbjct: 76 LTTVNSSDSDNGTTRTASTNSIG 98
>X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mRNA
for the RII-alpha subunit of cAMP dependent protein
kinase. ).
Length = 404
Score = 32.3 bits (70), Expect = 8.0
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
Query: 79 PNEAAAEAIKLF--YKEARLCSSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQN 136
P + A++ F +EAR +SV P R P P + K SE++E+++
Sbjct: 26 PPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDED 85
Query: 137 ITTPEPSTASR 147
+ P PS +R
Sbjct: 86 LEVPVPSRFNR 96
>BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, alpha protein.
Length = 382
Score = 32.3 bits (70), Expect = 8.0
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
Query: 79 PNEAAAEAIKLF--YKEARLCSSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQN 136
P + A++ F +EAR +SV P R P P + K SE++E+++
Sbjct: 26 PPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDED 85
Query: 137 ITTPEPSTASR 147
+ P PS +R
Sbjct: 86 LEVPVPSRFNR 96
>BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein.
Length = 382
Score = 32.3 bits (70), Expect = 8.0
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
Query: 79 PNEAAAEAIKLF--YKEARLCSSVTPNKVSRTDSNSYEPSPSSTLGPNHKNTSENKENQN 136
P + A++ F +EAR +SV P R P P + K SE++E+++
Sbjct: 26 PPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDED 85
Query: 137 ITTPEPSTASR 147
+ P PS +R
Sbjct: 86 LEVPVPSRFNR 96
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.136 0.402
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,156,366
Number of Sequences: 224733
Number of extensions: 5371026
Number of successful extensions: 14779
Number of sequences better than 10.0: 168
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 13986
Number of HSP's gapped (non-prelim): 273
length of query: 910
length of database: 73,234,838
effective HSP length: 97
effective length of query: 813
effective length of database: 51,435,737
effective search space: 41817254181
effective search space used: 41817254181
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 70 (32.3 bits)
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