Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001257-TA|BGIBMGA001257-PA|IPR013027|FAD-dependent
pyridine nucleotide-disulphide oxidoreductase
(472 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC021662-1|AAH21662.1| 500|Homo sapiens hypothetical protein FL... 374 e-103
AK025681-1|BAB15214.1| 463|Homo sapiens protein ( Homo sapiens ... 318 3e-86
CR456342-1|CAG30228.1| 605|Homo sapiens Em:AC002472.7 protein. 38 0.058
BC032485-1|AAH32485.1| 598|Homo sapiens apoptosis-inducing fact... 38 0.058
AK094844-1|BAC04434.1| 604|Homo sapiens protein ( Homo sapiens ... 38 0.058
AK055035-1|BAB70841.1| 605|Homo sapiens protein ( Homo sapiens ... 38 0.058
DQ016496-1|AAY84737.1| 261|Homo sapiens apoptosis-inducing fact... 36 0.31
CR457379-1|CAG33660.1| 613|Homo sapiens PDCD8 protein. 36 0.31
BC139738-1|AAI39739.1| 613|Homo sapiens apoptosis-inducing fact... 36 0.31
BC111065-1|AAI11066.1| 609|Homo sapiens apoptosis-inducing fact... 36 0.31
AL139234-3|CAI42779.1| 326|Homo sapiens programmed cell death 8... 36 0.31
AL139234-2|CAI42780.1| 609|Homo sapiens programmed cell death 8... 36 0.31
AL139234-1|CAI42778.1| 613|Homo sapiens programmed cell death 8... 36 0.31
AL049704-1|CAB41268.1| 326|Homo sapiens hypothetical protein pr... 36 0.31
AL049703-1|CAB41267.1| 609|Homo sapiens hypothetical protein pr... 36 0.31
AF131759-1|AAD20036.1| 443|Homo sapiens Unknown protein. 36 0.31
AF100928-1|AAD16436.1| 613|Homo sapiens apoptosis-inducing fact... 36 0.31
X15722-1|CAA33744.1| 479|Homo sapiens protein ( Human mRNA for ... 34 0.94
BC069244-1|AAH69244.1| 522|Homo sapiens glutathione reductase p... 34 0.94
AY338490-1|AAP88037.1| 479|Homo sapiens glutathione reductase p... 34 0.94
AF228704-1|AAF37574.1| 522|Homo sapiens mitochondrial glutathio... 34 0.94
AF228703-2|AAF37573.1| 479|Homo sapiens cytosolic glutathione r... 34 0.94
AF228703-1|AAF37572.1| 522|Homo sapiens mitochondrial glutathio... 34 0.94
BC023601-1|AAH23601.1| 373|Homo sapiens AIFM2 protein protein. 34 1.2
BC006121-1|AAH06121.1| 373|Homo sapiens apoptosis-inducing fact... 34 1.2
AL731540-3|CAI13684.1| 373|Homo sapiens apoptosis-inducing fact... 34 1.2
AK027403-1|BAB55089.1| 373|Homo sapiens protein ( Homo sapiens ... 34 1.2
AF506757-1|AAM77596.1| 373|Homo sapiens AMID protein protein. 34 1.2
AF337957-1|AAL73229.1| 373|Homo sapiens p53-responsive gene 3 p... 34 1.2
DQ016500-1|AAY84741.1| 237|Homo sapiens apoptosis-inducing fact... 33 2.9
DQ016498-1|AAY84739.1| 324|Homo sapiens apoptosis-inducing fact... 33 2.9
AY795556-1|AAV54053.1| 226|Homo sapiens striatal apoptosis-indu... 33 2.9
AY795557-1|AAV54054.1| 225|Homo sapiens apoptosis-inducing fact... 32 3.8
AJ304852-1|CAC40984.1| 925|Homo sapiens sodium/calcium exchange... 31 8.8
>BC021662-1|AAH21662.1| 500|Homo sapiens hypothetical protein
FLJ22028 protein.
Length = 500
Score = 374 bits (921), Expect = e-103
Identities = 203/493 (41%), Positives = 295/493 (59%), Gaps = 33/493 (6%)
Query: 8 YLIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETEATS 67
+++VGGGIAGVTC E LA P + ++LVTAS ++K V+N +K + FDV E +T
Sbjct: 13 FVVVGGGIAGVTCAEQLATHFPSEDILLVTASPVIKAVTNFKQISKILEEFDVEEQSSTM 72
Query: 68 LQKIHPNLKIIYDSLKHLDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLG 127
L K PN+K+I +K L +E+ +T+ G Y +C+C G P+LI + + VLG
Sbjct: 73 LGKRFPNIKVIESGVKQLKSEEHCIVTEDGNQHVYKKLCLCAGAKPKLICEG--NPYVLG 130
Query: 128 IRDTESVKDFQQKLKTGRRMVIVGNGGIASEIVHATSGIEKVWVIRDDYISATFIDPGAA 187
IRDT+S ++FQ++L +R++I+GNGGIA E+V+ G E +W I+D I TF D GAA
Sbjct: 131 IRDTDSAQEFQKQLTKAKRIMIIGNGGIALELVYEIEGCEVIWAIKDKAIGNTFFDAGAA 190
Query: 188 EFFQETFKNENERKNQNTVLRRHIYSEEDSLVSLNKNLKS----AALGPDWYRKLENIKS 243
EF T K E+ +R Y+ E K+ +ALGPDW+ L N+K
Sbjct: 191 EFL--TSKLIAEKSEAKIAHKRTRYTTEGRKKEARSKSKADNVGSALGPDWHEGL-NLKG 247
Query: 244 DRGVQ---------ELEIVYKAEVESVLE--------DNKNE------YPLRVQLTNSQL 280
+ E++ +Y + +L+ D+K+ +P+ V+LTN ++
Sbjct: 248 TKEFSHKIHLETMCEVKKIYLQDEFRILKKKSFTFPRDHKSVTADTEMWPVYVELTNEKI 307
Query: 281 VECDFLISATGVEPSVN-FTWDKVPEKGQDGGLAVNEFQETSIKNVFAAGDVASAAWEHA 339
CDF++SATGV P+V F + G+DGGL V++ TS+ +++AAGD+ + +W+ +
Sbjct: 308 YGCDFIVSATGVTPNVEPFLHGNSFDLGEDGGLKVDDHMHTSLPDIYAAGDICTTSWQLS 367
Query: 340 PHWFQLRLWTQARQMAGMAAKAMHGRITNQEVLQDFCFELFTHCTKLFGYRVILLGKYNG 399
P W Q+RLWTQARQM AAK M + + DF FELF H TK F Y+V+LLGKYN
Sbjct: 368 PVWQQMRLWTQARQMGWYAAKCMAAASSGDSIDMDFSFELFAHVTKFFNYKVVLLGKYNA 427
Query: 400 QGLGTDYEILLRTTPNVEYIKFVLKEGKLQGAILIGETDLEEMCENLILDQIDLSPFGXX 459
QGLG+D+E++LR T EYIK V++ G++ GA+LIGETDLEE ENLIL+Q++LS +G
Sbjct: 428 QGLGSDHELMLRCTKGREYIKVVMQNGRMMGAVLIGETDLEETFENLILNQMNLSSYGED 487
Query: 460 XXXXXXXXXXYFD 472
YFD
Sbjct: 488 LLDPNIDIEDYFD 500
>AK025681-1|BAB15214.1| 463|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22028 fis, clone HEP08589. ).
Length = 463
Score = 318 bits (781), Expect = 3e-86
Identities = 174/434 (40%), Positives = 257/434 (59%), Gaps = 33/434 (7%)
Query: 8 YLIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETEATS 67
+++VGGGIAGVTC E LA P + ++LVTAS ++K V+N +K + FDV E +T
Sbjct: 13 FVVVGGGIAGVTCAEQLATHFPSEDILLVTASPVIKAVTNFKQISKILEEFDVEEQSSTM 72
Query: 68 LQKIHPNLKIIYDSLKHLDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLG 127
L K PN+K+I +K L +E+ +T+ G Y +C+C G P+LI + + VLG
Sbjct: 73 LGKRFPNIKVIESGVKQLKSEEHCIVTEDGNQHVYKKLCLCAGAKPKLICE--GNPYVLG 130
Query: 128 IRDTESVKDFQQKLKTGRRMVIVGNGGIASEIVHATSGIEKVWVIRDDYISATFIDPGAA 187
IRDT+S ++FQ++L +R++I+GNGGIA E+V+ G E +W I+D I TF D GAA
Sbjct: 131 IRDTDSAQEFQKQLTKAKRIMIIGNGGIALELVYEIEGCEVIWAIKDKAIGNTFFDAGAA 190
Query: 188 EFFQETFKNENERKNQNTVLRRHIYSEEDSLVSLNKNLKS----AALGPDWYRKLENIKS 243
EF T K E+ +R Y+ E K+ +ALGPDW+ L N+K
Sbjct: 191 EFL--TSKLIAEKSEAKIAHKRTRYTTEGRKKEARSKSKADNVGSALGPDWHEGL-NLKG 247
Query: 244 DRGVQ---------ELEIVYKAEVESVLE--------DNKN------EYPLRVQLTNSQL 280
+ E++ +Y + +L+ D+K+ +P+ V+LTN ++
Sbjct: 248 TKEFSHKIHLETMCEVKKIYLQDEFRILKKKSFTFPRDHKSVTADTEMWPVYVELTNEKI 307
Query: 281 VECDFLISATGVEPSVN-FTWDKVPEKGQDGGLAVNEFQETSIKNVFAAGDVASAAWEHA 339
CDF++SATGV P+V F + G+DGGL V++ TS+ +++AAGD+ + +W+ +
Sbjct: 308 YGCDFIVSATGVTPNVEPFLHGNSFDLGEDGGLKVDDHMHTSLPDIYAAGDICTTSWQLS 367
Query: 340 PHWFQLRLWTQARQMAGMAAKAMHGRITNQEVLQDFCFELFTHCTKLFGYRVILLGKYNG 399
P W Q+RLWTQARQM AAK M + + DF FELF H TK F Y+V+LLGKYN
Sbjct: 368 PVWQQMRLWTQARQMGWYAAKCMAAASSGDSIDMDFSFELFAHVTKFFNYKVVLLGKYNA 427
Query: 400 QGLGTDYEILLRTT 413
QGLG+D+E++LR T
Sbjct: 428 QGLGSDHELMLRCT 441
>CR456342-1|CAG30228.1| 605|Homo sapiens Em:AC002472.7 protein.
Length = 605
Score = 38.3 bits (85), Expect = 0.058
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 273 VQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQDGGLAVNEFQETSIKNVFAAGDVA 332
V L +S++V D + G P+ F G + VN+ +T++ VFAAGD
Sbjct: 410 VVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAV 469
Query: 333 S--AAWE-----HAPHW 342
+ AW + PHW
Sbjct: 470 TFPLAWRNNRKVNIPHW 486
Score = 37.9 bits (84), Expect = 0.076
Identities = 38/160 (23%), Positives = 66/160 (41%), Gaps = 11/160 (6%)
Query: 5 NTTYLIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETE 64
+T LIVG G AG+ C ETL +VL T + K + D +
Sbjct: 194 STNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDR-----PKLSKSLDTQPEQ 248
Query: 65 ATSLQKIH---PNLKIIYDS-LKHLDTEKQKALTDKGVHIQYDVICICTGGIPRLIS-DS 119
K ++++ ++ + +D +K + G ++Y + + G P+ +S
Sbjct: 249 LALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKG 308
Query: 120 KNSKRVLGIRDTESVKDFQQKLKTGRRMVIVGNGGIASEI 159
K + V IR E +L GR +V+VG G + E+
Sbjct: 309 KEVENVFTIRTPEDANRVV-RLARGRNVVVVGAGFLGMEV 347
>BC032485-1|AAH32485.1| 598|Homo sapiens apoptosis-inducing factor,
mitochondrion-associated, 3 protein.
Length = 598
Score = 38.3 bits (85), Expect = 0.058
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 273 VQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQDGGLAVNEFQETSIKNVFAAGDVA 332
V L +S++V D + G P+ F G + VN+ +T++ VFAAGD
Sbjct: 410 VVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAV 469
Query: 333 S--AAWE-----HAPHW 342
+ AW + PHW
Sbjct: 470 TFPLAWRNNRKVNIPHW 486
Score = 37.9 bits (84), Expect = 0.076
Identities = 38/160 (23%), Positives = 66/160 (41%), Gaps = 11/160 (6%)
Query: 5 NTTYLIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETE 64
+T LIVG G AG+ C ETL +VL T + K + D +
Sbjct: 194 STNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDR-----PKLSKSLDTQPEQ 248
Query: 65 ATSLQKIH---PNLKIIYDS-LKHLDTEKQKALTDKGVHIQYDVICICTGGIPRLIS-DS 119
K ++++ ++ + +D +K + G ++Y + + G P+ +S
Sbjct: 249 LALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKG 308
Query: 120 KNSKRVLGIRDTESVKDFQQKLKTGRRMVIVGNGGIASEI 159
K + V IR E +L GR +V+VG G + E+
Sbjct: 309 KEVENVFTIRTPEDANRVV-RLARGRNVVVVGAGFLGMEV 347
>AK094844-1|BAC04434.1| 604|Homo sapiens protein ( Homo sapiens
cDNA FLJ37525 fis, clone BRCAN2009156, moderately
similar to Xenopus laevis mRNA for Nfrl. ).
Length = 604
Score = 38.3 bits (85), Expect = 0.058
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 273 VQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQDGGLAVNEFQETSIKNVFAAGDVA 332
V L +S++V D + G P+ F G + VN+ +T++ VFAAGD
Sbjct: 416 VVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAV 475
Query: 333 S--AAWE-----HAPHW 342
+ AW + PHW
Sbjct: 476 TFPLAWRNNRKVNIPHW 492
Score = 37.9 bits (84), Expect = 0.076
Identities = 38/160 (23%), Positives = 66/160 (41%), Gaps = 11/160 (6%)
Query: 5 NTTYLIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETE 64
+T LIVG G AG+ C ETL +VL T + K + D +
Sbjct: 200 STNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDR-----PKLSKSLDTQPEQ 254
Query: 65 ATSLQKIH---PNLKIIYDS-LKHLDTEKQKALTDKGVHIQYDVICICTGGIPRLIS-DS 119
K ++++ ++ + +D +K + G ++Y + + G P+ +S
Sbjct: 255 LALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKG 314
Query: 120 KNSKRVLGIRDTESVKDFQQKLKTGRRMVIVGNGGIASEI 159
K + V IR E +L GR +V+VG G + E+
Sbjct: 315 KEVENVFTIRTPEDANRVV-RLARGRNVVVVGAGFLGMEV 353
>AK055035-1|BAB70841.1| 605|Homo sapiens protein ( Homo sapiens
cDNA FLJ30473 fis, clone BRAWH1000094, moderately
similar to Xenopus laevis mRNA for Nfrl. ).
Length = 605
Score = 38.3 bits (85), Expect = 0.058
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 273 VQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQDGGLAVNEFQETSIKNVFAAGDVA 332
V L +S++V D + G P+ F G + VN+ +T++ VFAAGD
Sbjct: 410 VVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAV 469
Query: 333 S--AAWE-----HAPHW 342
+ AW + PHW
Sbjct: 470 TFPLAWRNNRKVNIPHW 486
Score = 37.9 bits (84), Expect = 0.076
Identities = 38/160 (23%), Positives = 66/160 (41%), Gaps = 11/160 (6%)
Query: 5 NTTYLIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETE 64
+T LIVG G AG+ C ETL +VL T + K + D +
Sbjct: 194 STNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDR-----PKLSKSLDTQPEQ 248
Query: 65 ATSLQKIH---PNLKIIYDS-LKHLDTEKQKALTDKGVHIQYDVICICTGGIPRLIS-DS 119
K ++++ ++ + +D +K + G ++Y + + G P+ +S
Sbjct: 249 LALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKG 308
Query: 120 KNSKRVLGIRDTESVKDFQQKLKTGRRMVIVGNGGIASEI 159
K + V IR E +L GR +V+VG G + E+
Sbjct: 309 KEVENVFTIRTPEDANRVV-RLARGRNVVVVGAGFLGMEV 347
>DQ016496-1|AAY84737.1| 261|Homo sapiens apoptosis-inducing factor
short isoform 1 protein.
Length = 261
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 27 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 84
Query: 329 GDVA 332
GD A
Sbjct: 85 GDAA 88
>CR457379-1|CAG33660.1| 613|Homo sapiens PDCD8 protein.
Length = 613
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 379 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 436
Query: 329 GDVA 332
GD A
Sbjct: 437 GDAA 440
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 236 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 295
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 296 ISREVKSITIIGGGFLGSELACA 318
>BC139738-1|AAI39739.1| 613|Homo sapiens apoptosis-inducing factor,
mitochondrion-associated, 1 protein.
Length = 613
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 379 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 436
Query: 329 GDVA 332
GD A
Sbjct: 437 GDAA 440
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 236 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 295
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 296 ISREVKSITIIGGGFLGSELACA 318
>BC111065-1|AAI11066.1| 609|Homo sapiens apoptosis-inducing factor,
mitochondrion-associated, 1 protein.
Length = 609
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 375 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 432
Query: 329 GDVA 332
GD A
Sbjct: 433 GDAA 436
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 232 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 291
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 292 ISREVKSITIIGGGFLGSELACA 314
>AL139234-3|CAI42779.1| 326|Homo sapiens programmed cell death 8
(apoptosis-inducing factor) protein.
Length = 326
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 92 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 149
Query: 329 GDVA 332
GD A
Sbjct: 150 GDAA 153
>AL139234-2|CAI42780.1| 609|Homo sapiens programmed cell death 8
(apoptosis-inducing factor) protein.
Length = 609
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 375 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 432
Query: 329 GDVA 332
GD A
Sbjct: 433 GDAA 436
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 232 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 291
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 292 ISREVKSITIIGGGFLGSELACA 314
>AL139234-1|CAI42778.1| 613|Homo sapiens programmed cell death 8
(apoptosis-inducing factor) protein.
Length = 613
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 379 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 436
Query: 329 GDVA 332
GD A
Sbjct: 437 GDAA 440
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 236 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 295
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 296 ISREVKSITIIGGGFLGSELACA 318
>AL049704-1|CAB41268.1| 326|Homo sapiens hypothetical protein
protein.
Length = 326
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 92 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 149
Query: 329 GDVA 332
GD A
Sbjct: 150 GDAA 153
>AL049703-1|CAB41267.1| 609|Homo sapiens hypothetical protein
protein.
Length = 609
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 375 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 432
Query: 329 GDVA 332
GD A
Sbjct: 433 GDAA 436
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 232 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 291
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 292 ISREVKSITIIGGGFLGSELACA 314
>AF131759-1|AAD20036.1| 443|Homo sapiens Unknown protein.
Length = 443
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 209 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 266
Query: 329 GDVA 332
GD A
Sbjct: 267 GDAA 270
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 66 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 125
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 126 ISREVKSITIIGGGFLGSELACA 148
>AF100928-1|AAD16436.1| 613|Homo sapiens apoptosis-inducing factor
AIF protein.
Length = 613
Score = 35.9 bits (79), Expect = 0.31
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 271 LRVQLTNSQLVECDFLISATGVEPSVNFTWDKVPEKGQD-GGLAVN-EFQETSIKNVFAA 328
L ++L + + VE D +++A G+EP+V E D GG VN E Q S N++ A
Sbjct: 379 LLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVA 436
Query: 329 GDVA 332
GD A
Sbjct: 437 GDAA 440
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 236 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 295
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 296 ISREVKSITIIGGGFLGSELACA 318
>X15722-1|CAA33744.1| 479|Homo sapiens protein ( Human mRNA for
glutathione reductase (EC 1.6.4.2). ).
Length = 479
Score = 34.3 bits (75), Expect = 0.94
Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 278 SQLVECDFLISATGVEPSV-NFTWDKVPEKGQDGG-LAVNEFQETSIKNVFAAGDVASAA 335
+ + + D L+ A G P+ + + +K+ + D G + V+EFQ T++K ++A GDV A
Sbjct: 278 TMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKA 337
>BC069244-1|AAH69244.1| 522|Homo sapiens glutathione reductase
protein.
Length = 522
Score = 34.3 bits (75), Expect = 0.94
Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 278 SQLVECDFLISATGVEPSV-NFTWDKVPEKGQDGG-LAVNEFQETSIKNVFAAGDVASAA 335
+ + + D L+ A G P+ + + +K+ + D G + V+EFQ T++K ++A GDV A
Sbjct: 321 TMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKA 380
>AY338490-1|AAP88037.1| 479|Homo sapiens glutathione reductase
protein.
Length = 479
Score = 34.3 bits (75), Expect = 0.94
Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 278 SQLVECDFLISATGVEPSV-NFTWDKVPEKGQDGG-LAVNEFQETSIKNVFAAGDVASAA 335
+ + + D L+ A G P+ + + +K+ + D G + V+EFQ T++K ++A GDV A
Sbjct: 278 TMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKA 337
>AF228704-1|AAF37574.1| 522|Homo sapiens mitochondrial glutathione
reductase protein.
Length = 522
Score = 34.3 bits (75), Expect = 0.94
Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 278 SQLVECDFLISATGVEPSV-NFTWDKVPEKGQDGG-LAVNEFQETSIKNVFAAGDVASAA 335
+ + + D L+ A G P+ + + +K+ + D G + V+EFQ T++K ++A GDV A
Sbjct: 321 TMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKA 380
>AF228703-2|AAF37573.1| 479|Homo sapiens cytosolic glutathione
reductase protein.
Length = 479
Score = 34.3 bits (75), Expect = 0.94
Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 278 SQLVECDFLISATGVEPSV-NFTWDKVPEKGQDGG-LAVNEFQETSIKNVFAAGDVASAA 335
+ + + D L+ A G P+ + + +K+ + D G + V+EFQ T++K ++A GDV A
Sbjct: 278 TMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKA 337
>AF228703-1|AAF37572.1| 522|Homo sapiens mitochondrial glutathione
reductase protein.
Length = 522
Score = 34.3 bits (75), Expect = 0.94
Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 278 SQLVECDFLISATGVEPSV-NFTWDKVPEKGQDGG-LAVNEFQETSIKNVFAAGDVASAA 335
+ + + D L+ A G P+ + + +K+ + D G + V+EFQ T++K ++A GDV A
Sbjct: 321 TMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKA 380
>BC023601-1|AAH23601.1| 373|Homo sapiens AIFM2 protein protein.
Length = 373
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Query: 9 LIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETEATSL 68
++VGGG AGV + +PEK + L+ + + + + + + + + L
Sbjct: 146 VVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQVALADKELLPSVRQEVKEILLRKGVQLLL 205
Query: 69 QKIHPNLKIIYDSLKHLDTEKQKALTDKGVHIQYDVICICTG 110
+ NL+ + L E K TDKG + +++ +CTG
Sbjct: 206 SERVSNLEEL--PLNEY-REYIKVQTDKGTEVATNLVILCTG 244
>BC006121-1|AAH06121.1| 373|Homo sapiens apoptosis-inducing factor,
mitochondrion-associated, 2 protein.
Length = 373
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Query: 9 LIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETEATSL 68
++VGGG AGV + +PEK + L+ + + + + + + + + L
Sbjct: 146 VVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQVALADKELLPSVRQEVKEILLRKGVQLLL 205
Query: 69 QKIHPNLKIIYDSLKHLDTEKQKALTDKGVHIQYDVICICTG 110
+ NL+ + L E K TDKG + +++ +CTG
Sbjct: 206 SERVSNLEEL--PLNEY-REYIKVQTDKGTEVATNLVILCTG 244
>AL731540-3|CAI13684.1| 373|Homo sapiens apoptosis-inducing factor
(AIF)-homologous mitochondrion-associated inducer of
protein.
Length = 373
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Query: 9 LIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETEATSL 68
++VGGG AGV + +PEK + L+ + + + + + + + + L
Sbjct: 146 VVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQVALADKELLPSVRQEVKEILLRKGVQLLL 205
Query: 69 QKIHPNLKIIYDSLKHLDTEKQKALTDKGVHIQYDVICICTG 110
+ NL+ + L E K TDKG + +++ +CTG
Sbjct: 206 SERVSNLEEL--PLNEY-REYIKVQTDKGTEVATNLVILCTG 244
>AK027403-1|BAB55089.1| 373|Homo sapiens protein ( Homo sapiens
cDNA FLJ14497 fis, clone NT2RM1000039. ).
Length = 373
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Query: 9 LIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETEATSL 68
++VGGG AGV + +PEK + L+ + + + + + + + + L
Sbjct: 146 VVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQVALADKELLPSVRQEVKEILLRKGVQLLL 205
Query: 69 QKIHPNLKIIYDSLKHLDTEKQKALTDKGVHIQYDVICICTG 110
+ NL+ + L E K TDKG + +++ +CTG
Sbjct: 206 SERVSNLEEL--PLNEY-REYIKVQTDKGTEVATNLVILCTG 244
>AF506757-1|AAM77596.1| 373|Homo sapiens AMID protein protein.
Length = 373
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Query: 9 LIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETEATSL 68
++VGGG AGV + +PEK + L+ + + + + + + + + L
Sbjct: 146 VVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQVALADKELLPSVRQEVKEILLRKGVQLLL 205
Query: 69 QKIHPNLKIIYDSLKHLDTEKQKALTDKGVHIQYDVICICTG 110
+ NL+ + L E K TDKG + +++ +CTG
Sbjct: 206 SERVSNLEEL--PLNEY-REYIKVQTDKGTEVATNLVILCTG 244
>AF337957-1|AAL73229.1| 373|Homo sapiens p53-responsive gene 3
protein.
Length = 373
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Query: 9 LIVGGGIAGVTCVETLAILHPEKTLVLVTASTLVKNVSNVTFFAKTIVNFDVNETEATSL 68
++VGGG AGV + +PEK + L+ + + + + + + + + L
Sbjct: 146 VVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQVALADKELLPSVRQEVKEILLRKGVQLLL 205
Query: 69 QKIHPNLKIIYDSLKHLDTEKQKALTDKGVHIQYDVICICTG 110
+ NL+ + L E K TDKG + +++ +CTG
Sbjct: 206 SERVSNLEEL--PLNEY-REYIKVQTDKGTEVATNLVILCTG 244
>DQ016500-1|AAY84741.1| 237|Homo sapiens apoptosis-inducing factor
short isoform 3 protein.
Length = 237
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 149 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 208
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 209 ISREVKSITIIGGGFLGSELACA 231
>DQ016498-1|AAY84739.1| 324|Homo sapiens apoptosis-inducing factor
short isoform 2 protein.
Length = 324
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 236 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 295
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 296 ISREVKSITIIGGGFLGSELACA 318
>AY795556-1|AAV54053.1| 226|Homo sapiens striatal
apoptosis-inducing factor protein.
Length = 226
Score = 32.7 bits (71), Expect = 2.9
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 126 LDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 185
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 186 ISREVKSITIIGGGFLGSELACA 208
>AY795557-1|AAV54054.1| 225|Homo sapiens apoptosis-inducing factor
protein.
Length = 225
Score = 32.3 bits (70), Expect = 3.8
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 85 LDTEKQKALTDKGVHIQYDVICICTGGIPRLISDSKNSKRVLGIRDT--ESVKDFQQKLK 142
LD + G I Y+ I TGG PR +S + + R T + DF+ K
Sbjct: 125 LDVRGNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEK 184
Query: 143 TGRR---MVIVGNGGIASEIVHA 162
R + I+G G + SE+ A
Sbjct: 185 ISREVKSITIIGGGFLGSELACA 207
>AJ304852-1|CAC40984.1| 925|Homo sapiens sodium/calcium exchanger
SCL8A3 protein.
Length = 925
Score = 31.1 bits (67), Expect = 8.8
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 154 GIASEIVHATSGIEKVWVIRDDYISATFIDPGAAEFFQETFKNENERKNQNTVLRRHIYS 213
G+ V TSG ++ + T G E F++T+ E E KN TV HI
Sbjct: 546 GVMEVKVLRTSGARGTVIVPFRTVEGTA--KGGGEDFEDTY-GELEFKNDETVKTIHIKV 602
Query: 214 EEDSLVSLNKNLKSAALGP 232
+D NKN +GP
Sbjct: 603 IDDEAYEKNKNYFIEMMGP 621
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.135 0.393
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 62,271,842
Number of Sequences: 224733
Number of extensions: 2481095
Number of successful extensions: 5666
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 5609
Number of HSP's gapped (non-prelim): 75
length of query: 472
length of database: 73,234,838
effective HSP length: 93
effective length of query: 379
effective length of database: 52,334,669
effective search space: 19834839551
effective search space used: 19834839551
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 67 (31.1 bits)
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