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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001255-TA|BGIBMGA001255-PA|IPR001054|Adenylyl cyclase
class-3/4/guanylyl cyclase
         (607 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_51990| Best HMM Match : Guanylate_cyc (HMM E-Value=0)              263   3e-70
SB_37259| Best HMM Match : No HMM Matches (HMM E-Value=.)              99   5e-21
SB_37135| Best HMM Match : Guanylate_cyc (HMM E-Value=0)               97   5e-20
SB_11488| Best HMM Match : No HMM Matches (HMM E-Value=.)              96   8e-20
SB_10830| Best HMM Match : No HMM Matches (HMM E-Value=.)              90   5e-18
SB_43991| Best HMM Match : No HMM Matches (HMM E-Value=.)              85   2e-16
SB_50980| Best HMM Match : Guanylate_cyc (HMM E-Value=0)               80   4e-15
SB_38875| Best HMM Match : No HMM Matches (HMM E-Value=.)              79   1e-14
SB_58457| Best HMM Match : Guanylate_cyc (HMM E-Value=0)               67   4e-11
SB_58458| Best HMM Match : Guanylate_cyc (HMM E-Value=1.2e-36)         59   9e-09
SB_50731| Best HMM Match : Guanylate_cyc (HMM E-Value=0.76)            58   2e-08
SB_28889| Best HMM Match : ANF_receptor (HMM E-Value=1.1e-34)          57   5e-08
SB_13681| Best HMM Match : Guanylate_cyc (HMM E-Value=2.8e-27)         54   3e-07
SB_21756| Best HMM Match : No HMM Matches (HMM E-Value=.)              52   2e-06
SB_29093| Best HMM Match : HNOBA (HMM E-Value=0)                       47   4e-05
SB_10421| Best HMM Match : Guanylate_cyc (HMM E-Value=0)               44   4e-04
SB_29094| Best HMM Match : Guanylate_cyc (HMM E-Value=7.9e-07)         42   0.001
SB_4482| Best HMM Match : No HMM Matches (HMM E-Value=.)               41   0.003
SB_34632| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   1.5  
SB_55010| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   2.0  
SB_24479| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   2.7  
SB_53658| Best HMM Match : No HMM Matches (HMM E-Value=.)              29   8.2  
SB_48470| Best HMM Match : HNOB (HMM E-Value=0)                        29   8.2  

>SB_51990| Best HMM Match : Guanylate_cyc (HMM E-Value=0)
          Length = 1055

 Score =  263 bits (644), Expect = 3e-70
 Identities = 128/250 (51%), Positives = 177/250 (70%), Gaps = 2/250 (0%)

Query: 357  NREFEISYRLSFYSNVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLKNTAKYSENHKD 416
            NR+ E+  R +F  +  A + K++ Q  + QADWLL ++ P+HV++ LK +  YS N+ +
Sbjct: 804  NRQLEMGVRRNFSGDAEAAKVKKKSQVHKQQADWLLLSLFPKHVSEALKTSDHYSMNYNN 863

Query: 417  VAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTI-GSTFM 475
              ++FASI+NF++ Y+E++  GKE +R+LNEL+ DFDELL+  ++  VEKIKT+ GSTFM
Sbjct: 864  AGVMFASIVNFSDFYEENFEGGKECIRVLNELVGDFDELLDNIEYMEVEKIKTVNGSTFM 923

Query: 476  AASGLNP-DLRHASRGTYDHLYQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDVTA 534
            A +GLN  D        Y+HL QL++FALEM  VVD FN  +  F F LRIG+N G VTA
Sbjct: 924  AGAGLNQEDNIRREIHPYEHLKQLVEFALEMFNVVDRFNEHMLGFKFKLRIGFNAGPVTA 983

Query: 535  GVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVLSARYEFEPRGSVYVKGKD 594
            GVIGTTKL YDIWGD VN+ASRMDSTGVP++IQV E+   +L+  + FE RG++ VKGK 
Sbjct: 984  GVIGTTKLLYDIWGDTVNLASRMDSTGVPEKIQVSESTKEMLNDFFIFERRGTIPVKGKG 1043

Query: 595  DMNVYLLVGK 604
             +  YL +G+
Sbjct: 1044 YVTTYLYLGR 1053



 Score =  100 bits (240), Expect = 3e-21
 Identities = 57/193 (29%), Positives = 102/193 (52%), Gaps = 14/193 (7%)

Query: 415 KDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTF 474
           ++V+I+FA I+ F +M   S     + +R+LN+L   FD L E   + H EKI T+G  +
Sbjct: 306 ENVSILFADIVGFTKM--SSNKSADQLVRLLNDLFGRFDRLTE---YNHCEKISTLGDCY 360

Query: 475 MAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDVTA 534
              +G         + T +H    ++  L+M + +  F++D  + D  +R+G + G V  
Sbjct: 361 YCVAG-------CPKPTPNHATYCVEMGLDMLEQIKEFDNDT-DNDVDMRVGVHTGTVLC 412

Query: 535 GVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVLSARYEFE-PRGSVYVKGK 593
           G++GT +  +D+W + V +A+RM++ G+P R+ + EA V  L  +Y  E   G       
Sbjct: 413 GIVGTKRFKFDVWSNDVTLANRMETAGLPGRVHITEATVGFLRDQYIVENGHGETRNAAL 472

Query: 594 DDMNVYLLVGKKD 606
             +  Y +VG+K+
Sbjct: 473 KGITTYFIVGRKN 485



 Score = 40.3 bits (90), Expect = 0.004
 Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 2/91 (2%)

Query: 55  QKLRKQSDLQLIRCVQDNARSGINYFVQPPINRFTLCFESDEMERHYRDKAHRSDDCEDL 114
           + LR  +D QL+  + +    G  YF   P++  TL F   E+E+ Y+++   S      
Sbjct: 614 ETLRTSNDQQLVHLMSEQG-VGDEYF-HAPVSTCTLQFYDKELEQQYQNEGQDSTLLNPS 671

Query: 115 PPTLTTSRFNTALDILVSALIFLAVSASAFV 145
             T  + + N   D+L+S ++F  +    F+
Sbjct: 672 VTTFASPKVNFFTDVLLSNIVFFTICVLCFL 702



 Score = 37.9 bits (84), Expect = 0.023
 Identities = 11/40 (27%), Positives = 27/40 (67%)

Query: 241 QSFYVYLLCISIVHFCNFTQMNWLAKNTLVTLYAGVFLFV 280
           ++F+ Y++ ++++HFCNFTQ+    K +L  ++   ++ +
Sbjct: 726 RNFFSYIVAVALLHFCNFTQLTSWMKTSLAAVFTMTYIIL 765


>SB_37259| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1690

 Score =   99 bits (238), Expect = 5e-21
 Identities = 73/256 (28%), Positives = 134/256 (52%), Gaps = 23/256 (8%)

Query: 357  NREFEISYRLSFYSNVVANRDKQR---VQNMRNQADWLLHNIIPRHVADQLK-NTAKYSE 412
            + +F+  Y L+    ++ ++ +Q    +   +   D LL++++P  VA++L+ N    +E
Sbjct: 1401 SEQFKAEYVLTQQLEILTDKLRQTHNALAEKKQLTDQLLYSVLPPSVANELRHNRPVQAE 1460

Query: 413  NHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGS 472
              + V ++F+ I++F ++   S  K  E + +LN +   FD L + P    V K++T+G 
Sbjct: 1461 RAEMVTLLFSGIVDFAQICKNS--KPMEIVMLLNNIYTKFDMLTD-PSINDVYKVETVGD 1517

Query: 473  TFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDV 532
             +MA SGL P+     R  + H   + + AL+M+ V  +  H   +    ++IG + G+V
Sbjct: 1518 KYMAVSGL-PE-----RCAF-HARSICNMALDMKHVTQSIIHKGDKIQ--IKIGIHSGEV 1568

Query: 533  TAGVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVL------SARYEFEPRG 586
             AGV+G     Y ++G+ VN+ SR ++TG P ++ + E     L         + FE RG
Sbjct: 1569 VAGVVGHKTPRYCLFGNTVNLTSRTETTGAPGQVNITEFTYRCLLEPECQDPSFVFERRG 1628

Query: 587  SVYVKGKDD-MNVYLL 601
             V +KG+ + M  YLL
Sbjct: 1629 PVAMKGRQEPMVTYLL 1644



 Score = 92.3 bits (219), Expect = 1e-18
 Identities = 70/248 (28%), Positives = 124/248 (50%), Gaps = 16/248 (6%)

Query: 357  NREFEISYRLSFYSNVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLKNTAKYSEN-HK 415
            N EF++S RL   ++ +    ++ ++N +   D LL++I+P  VA+ L+     + N ++
Sbjct: 857  NAEFKLSQRLEILTDKLQQTSRE-LENEQQLNDRLLYSILPASVANDLRLRKPVNANKYE 915

Query: 416  DVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFM 475
             V I+F+ I++F   Y     +  E + +LNE+  +FD+L +      + K++T+G  +M
Sbjct: 916  IVTIMFSGIVDFTN-YCNKIKEPMEIVEMLNEVYTEFDQLTDSND--DIYKVETVGDKYM 972

Query: 476  AASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDVTAG 535
            A SGL             H   + + AL+M  +         +    + IG + G+V AG
Sbjct: 973  AVSGLPTRCDK-------HALNIANLALDMIDISKGMKAKGIQLQ--VTIGIHSGEVVAG 1023

Query: 536  VIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVLSARYEFEPRGSVYVKGKDD 595
            V+G  K  Y ++G+ VN+ SR ++TG+  +I V E      +A  E E      +   DD
Sbjct: 1024 VVGQKKPRYCLFGNTVNLTSRTETTGLKGKINVSEYAYR-RAAELEIEGHFLQRII-YDD 1081

Query: 596  MNVYLLVG 603
            +  Y LVG
Sbjct: 1082 VMTYSLVG 1089



 Score = 59.7 bits (138), Expect = 7e-09
 Identities = 48/191 (25%), Positives = 90/191 (47%), Gaps = 16/191 (8%)

Query: 381 VQNMRNQADWLLHNIIPRHVADQLKNTAKYSENH-KDVAIIFASIINFNEMYDESYLKGK 439
           ++  + + + LL +I P  VA++L N       H ++V ++F+ I+ F  +  +      
Sbjct: 423 LEEEKKKTENLLSSIFPHDVANKLINKQPIPARHIQNVTMLFSDIVGFTAICGKC--SAM 480

Query: 440 EYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLM 499
           + + +L  L   FD+L          K++TIG  ++ A G+     H   GT +  Y + 
Sbjct: 481 DVVEMLKSLYTKFDKLCGELDLY---KVETIGDAYVVAGGVQ---NHC--GTAEDAYHVA 532

Query: 500 DFALEMQKVVDNFNHDLFE--FDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRM 557
             A+ M   +D+    L        +R+G + G V +GV+GT    Y ++G  V +A++M
Sbjct: 533 LMAVGM---IDHIRDVLSPEGVPLKMRVGIHTGSVLSGVVGTKMPRYCLFGHDVTLANKM 589

Query: 558 DSTGVPQRIQV 568
           +S     RI +
Sbjct: 590 ESESEAGRINI 600


>SB_37135| Best HMM Match : Guanylate_cyc (HMM E-Value=0)
          Length = 584

 Score = 96.7 bits (230), Expect = 5e-20
 Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 17/218 (7%)

Query: 379 QRVQNMRNQADWLLHNIIPRHVADQLKN---TAKYSENHKDVAIIFASIINFNEMYDESY 435
           + + N + + D LL+ +IP+ VAD+L+         E   +V I+F+ ++ F  +   S 
Sbjct: 372 RELDNEKLRTDALLYQMIPKTVADRLRKGEPALNTCETFSNVTILFSDVVGFTTIC--SL 429

Query: 436 LKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHL 495
           +   + + +LN +   FD+L E+    +V K++TIG  +M  SG+ P+     R  Y H 
Sbjct: 430 IAPMQVVTMLNCMYTTFDKLSEK---HNVYKVETIGDAYMVVSGI-PE-----RTKY-HA 479

Query: 496 YQLMDFALEMQKVVDNFNHDLFEFDFI-LRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIA 554
             + D AL M   +          D + +RIG + G V AGV+G     Y ++GD VN A
Sbjct: 480 EHVADMALNMLSAMPEIEDPAGLNDHLRIRIGIHTGTVVAGVVGLKMPRYCLFGDTVNTA 539

Query: 555 SRMDSTGVPQRIQVGEACVPVLS-ARYEFEPRGSVYVK 591
           SRM+STG+   I V E     L+ A Y  + RGS+ +K
Sbjct: 540 SRMESTGLAMAIHVSEDTQKFLAKANYALKQRGSMDIK 577


>SB_11488| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 250

 Score = 95.9 bits (228), Expect = 8e-20
 Identities = 65/235 (27%), Positives = 125/235 (53%), Gaps = 16/235 (6%)

Query: 371 NVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLK-NTAKYSENHKDVAIIFASIINFNE 429
           ++V  R +Q ++  +++ D LL+ ++PR +ADQLK      +E+  +V + +  I++F  
Sbjct: 22  SLVKERTRQ-LETEKSKTDELLYRMLPRLIADQLKAGLPLKAESFSEVTVFYCDIVDFTV 80

Query: 430 MYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASR 489
           +   S  +  + +++LN++ + FD ++ R     + K++T+G + +  SGL P+ R+ +R
Sbjct: 81  ITALS--EPMQVIKLLNDVYSLFDTIMGR---YDIYKVETVGDSCLVVSGL-PE-RNGNR 133

Query: 490 GTYDHLYQLMDFALEMQKVVDNFNHD-LFEFDFILRIGYNFGDVTAGVIGTTKLYYDIWG 548
               H  ++   +L +   V +F  + L +     R+G + G   AG++G  K  YDI+G
Sbjct: 134 ----HASEIAAMSLHLLNYVTDFRIEHLPDTRLEFRMGIHTGPCVAGIVGLKKPRYDIFG 189

Query: 549 DAVNIASRMDSTGVPQRIQVGEACVPVLS--ARYEFEPRGSVYVKGKDDMNVYLL 601
           + VNI   ++S G+PQ I V      +L+    +  E RG + +KG      Y L
Sbjct: 190 ETVNIVKHLESAGIPQSIHVSSPTCRLLTTLGGFMLETRGEMLIKGIGITTTYFL 244


>SB_10830| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1006

 Score = 89.8 bits (213), Expect = 5e-18
 Identities = 53/115 (46%), Positives = 65/115 (56%), Gaps = 4/115 (3%)

Query: 492 YDHLYQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAV 551
           +   Y  +D   E  + +   N  L +FD    +  NFG V AGVIG  K  YDIWGD V
Sbjct: 887 FSDFYTELDANGEGVECLRLLNEILADFD---EVSLNFGPVVAGVIGAHKPQYDIWGDTV 943

Query: 552 NIASRMDSTGVPQRIQVGEACVPVLSAR-YEFEPRGSVYVKGKDDMNVYLLVGKK 605
           N+ASRM STG    IQV +A   +LS R Y F+ RG V VKGK  M  Y L+GK+
Sbjct: 944 NVASRMYSTGKDNHIQVTKAMYEILSTRGYTFDCRGLVAVKGKGKMVTYWLLGKE 998



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 37/99 (37%), Positives = 58/99 (58%), Gaps = 8/99 (8%)

Query: 365 RLSFYSNVVANRDKQRVQNMRNQADWLLHNIIPRHVADQL------KNTAKYSENHKDVA 418
           RL F   + A  +K+ ++ +R     LL+NI+P HVA         KN   Y ++   VA
Sbjct: 819 RLDFLWKLQATEEKKEMEQLREYNKKLLYNILPVHVAQHFLGHKANKNEDLYYQSCDKVA 878

Query: 419 IIFASIINFNEMYDESYLKGK--EYLRILNELIADFDEL 455
           ++F++I NF++ Y E    G+  E LR+LNE++ADFDE+
Sbjct: 879 VMFSNICNFSDFYTELDANGEGVECLRLLNEILADFDEV 917



 Score = 64.1 bits (149), Expect = 3e-10
 Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 8/104 (7%)

Query: 460 QFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNFNHDLFEF 519
           Q  H  +IK +G  +   SGL PD R       DH +  ++  L M   + +F  D  + 
Sbjct: 498 QENHCLRIKILGDCYYCVSGL-PDPRP------DHAHSCIEMGLAMIDAI-SFVRDATQV 549

Query: 520 DFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVP 563
           +  +R+G + G V +GV+G  K  YD+W D V IA+ M+S G+P
Sbjct: 550 NLNMRVGVHMGKVHSGVLGLVKWQYDVWSDDVTIANHMESGGLP 593



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 14/107 (13%)

Query: 361 EISYRLSFYSNVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLKNTAK----------- 409
           EIS R +F         +  +Q      + LL +++PR+VA ++K+  +           
Sbjct: 349 EISQRQAFLETRRCIEARLTIQKENQNQERLLLSVLPRYVAMEMKDDIESGISQNSQFHK 408

Query: 410 -YSENHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDEL 455
            Y + H++V+I+FA I  F  +   S    +  ++ LNEL A FD+L
Sbjct: 409 IYIQRHENVSILFADIEGFTVL--SSQCTAQSLIKTLNELYARFDQL 453


>SB_43991| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1149

 Score = 84.6 bits (200), Expect = 2e-16
 Identities = 61/173 (35%), Positives = 93/173 (53%), Gaps = 20/173 (11%)

Query: 395  IIPRHVADQLKN-TAKYSENHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFD 453
            II + VA+QLK   A  +E+  +V I F+ I+ F  +  ES     + +  LN+L   FD
Sbjct: 856  IIIKPVAEQLKKGKAVEAESFNEVTIYFSDIVGFTSLSAES--TPMQVVTFLNDLYTIFD 913

Query: 454  ELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNFN 513
            ++++      V K++TIG  +M ASGL   +R+  R    H  ++   AL +   VD  +
Sbjct: 914  DIIQE---YDVYKVETIGDAYMVASGL--PIRNGRR----HAGEIAKMALHL---VDAVS 961

Query: 514  HDLF-----EFDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTG 561
            H+       E+   LR+G + G V AGV+G T   Y ++GD VN ASRM+S G
Sbjct: 962  HNFIVRHKPEYKLQLRVGCHTGPVVAGVVGNTMARYCLFGDTVNTASRMESNG 1014


>SB_50980| Best HMM Match : Guanylate_cyc (HMM E-Value=0)
          Length = 313

 Score = 80.2 bits (189), Expect = 4e-15
 Identities = 58/169 (34%), Positives = 89/169 (52%), Gaps = 16/169 (9%)

Query: 397 PRHVADQLKN-TAKYSENHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDEL 455
           P  VA+QLK   A  +E+  +V+I F+ I+ F  +  ES     + + +LN+L   FD++
Sbjct: 154 PGSVAEQLKKGKAVEAESFDEVSIYFSDIVGFTSLSAES--TPMQVVTLLNDLYTLFDDI 211

Query: 456 LERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDN---F 512
           +       V K++TIG  +M  SGL   +R+ SR    H  ++   +L +   V      
Sbjct: 212 IRE---YDVYKVETIGDAYMVVSGL--PIRNGSR----HAGEIARMSLHLVDAVQTEFCV 262

Query: 513 NHDLFEFDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTG 561
            H   E+   LR+G + G V AGV+G T   Y ++GD VN ASRM+S G
Sbjct: 263 RHKP-EYKLKLRVGIHSGPVVAGVVGNTMPRYCLFGDTVNTASRMESNG 310


>SB_38875| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1116

 Score = 78.6 bits (185), Expect = 1e-14
 Identities = 55/208 (26%), Positives = 100/208 (48%), Gaps = 28/208 (13%)

Query: 391 LLHNIIPRHVADQLK-------------NTAK--YSENHKDVAIIFASIINFNEMYDESY 435
           LL +++P+HVA+++              N  K  +   H   +I+FA I+ F E+   S 
Sbjct: 484 LLLSVLPKHVAEEMTKDFEGDGNPALTDNAFKKLFIRTHDTCSILFADIVGFTEL--SSK 541

Query: 436 LKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHL 495
              ++ +  LNEL A+FD+L  +    H  +IK +G  +   SGL+    HA        
Sbjct: 542 CTAEQLIVTLNELFANFDKLAAK---NHCLRIKILGDCYYCISGLDDSCNHALCA----- 593

Query: 496 YQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIAS 555
              ++  L+M + + +   +       +R+G + G V AGV+G  K  ++ W + V +A+
Sbjct: 594 ---VNMGLDMVEHIAHVREEKGVKSLNMRVGIHTGMVLAGVLGQRKWQFEAWSNDVTLAN 650

Query: 556 RMDSTGVPQRIQVGEACVPVLSARYEFE 583
            M+S G+P R+ + E  +  +   +E E
Sbjct: 651 HMESGGIPGRVHISEPTLNSIKDYFEVE 678



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 35/79 (44%), Positives = 49/79 (62%), Gaps = 1/79 (1%)

Query: 530  GDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQV-GEACVPVLSARYEFEPRGSV 588
            G + AGVIG  K +YDIWG+ VN+ASRM++TG    IQ+  +    +    + F  RG+V
Sbjct: 1028 GPIVAGVIGAKKPHYDIWGNTVNVASRMETTGKAGCIQITAQTYETIKDKDFVFVYRGAV 1087

Query: 589  YVKGKDDMNVYLLVGKKDT 607
             VKGK  +  Y L G+K+T
Sbjct: 1088 RVKGKGQLITYYLTGRKNT 1106


>SB_58457| Best HMM Match : Guanylate_cyc (HMM E-Value=0)
          Length = 410

 Score = 66.9 bits (156), Expect = 4e-11
 Identities = 64/225 (28%), Positives = 107/225 (47%), Gaps = 33/225 (14%)

Query: 385 RNQADWLLHNIIPRHVADQLK-NTAKYSENHKDVAIIFASIINFNEMYDESYLKGKEYLR 443
           + + D LL  ++P+ V DQLK   +  +E+  +V+I F+ I+ F E+  ES     + + 
Sbjct: 96  KKKTDALLERMLPKPVTDQLKRGKSVEAESFHEVSIYFSDIVGFTELSAES--SPLQVVS 153

Query: 444 ILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFAL 503
           +LN+L   FD+++       V K++TIG  +M  SGL   +R+ +R    H  ++   AL
Sbjct: 154 LLNDLYTLFDDIIRE---YDVYKVETIGDAYMVVSGL--PIRNGNR----HAGEIAKMAL 204

Query: 504 EMQKVVDNFNHDLFEFDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVP 563
            + + V        + +FI+R    +           KL   I  D + +   M    + 
Sbjct: 205 HLIEAV--------QTEFIVRYKPTY---------KLKLRVGIHSDLIVLI--MIVFSIA 245

Query: 564 QRIQVGEACVPVLS--ARYEFEPRGSVYVKGKDDMNVYLLVGKKD 606
            RI + E    +L     +  E RG VY+KGK +M+ Y LV  KD
Sbjct: 246 LRIHISEDTKRILDQLGGFVVEGRGEVYLKGKGNMHTYWLVDIKD 290


>SB_58458| Best HMM Match : Guanylate_cyc (HMM E-Value=1.2e-36)
          Length = 1065

 Score = 59.3 bits (137), Expect = 9e-09
 Identities = 49/167 (29%), Positives = 81/167 (48%), Gaps = 14/167 (8%)

Query: 371 NVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLKNTAKYS-ENHKDVAIIFASIINFNE 429
           ++V  R  Q     R   + LL+ ++P  VA  L +  + + EN  +V+I F+ I+ F  
Sbjct: 710 SLVEERTSQLADEKRKTEN-LLNRMLPPSVAKDLVHGKQVTAENFDEVSIFFSDIVGFTS 768

Query: 430 MYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASR 489
           +  ES     + + +LN+L   FDE++       V K++TIG  +M  SGL        R
Sbjct: 769 LSSES--TPLQVVDLLNDLYTLFDEIINN---YDVYKVETIGDAYMVVSGL------PIR 817

Query: 490 GTYDHLYQLMDFALEMQKVVDNFNHDLFEFDFI-LRIGYNFGDVTAG 535
             + H  ++   AL M + +D+F       D + LRIG + G V +G
Sbjct: 818 NGHQHAGEIATMALHMLREIDSFKIRHRPNDKLKLRIGIHSGMVVSG 864


>SB_50731| Best HMM Match : Guanylate_cyc (HMM E-Value=0.76)
          Length = 64

 Score = 58.0 bits (134), Expect = 2e-08
 Identities = 28/60 (46%), Positives = 36/60 (60%), Gaps = 2/60 (3%)

Query: 534 AGVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVL--SARYEFEPRGSVYVK 591
           AGV+G  K  YD++GD VN+ASRM+S GVP RI +   C   L     Y  E RG + +K
Sbjct: 5   AGVVGIKKPRYDVFGDTVNVASRMESNGVPNRIHISAECRKALLNLGGYHMERRGEIELK 64


>SB_28889| Best HMM Match : ANF_receptor (HMM E-Value=1.1e-34)
          Length = 933

 Score = 56.8 bits (131), Expect = 5e-08
 Identities = 40/142 (28%), Positives = 75/142 (52%), Gaps = 13/142 (9%)

Query: 372 VVANRDKQRVQNMRNQADWLLHNIIPRHVADQLKNTAKY-SENHKDVAIIFASIINFNEM 430
           +V  R +Q + + + + D LL+ ++PR++A+ LK      +E++  V I F+ I+ F E+
Sbjct: 714 IVDERTRQ-LADEKAKTDELLYKMLPRYIAESLKRGEPVIAESYSSVTIFFSDIVGFTEL 772

Query: 431 YDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRG 490
              S     + + +LN+L   FD ++++     V K++TIG  +M  SGL   +R+  R 
Sbjct: 773 AAAS--TPLQVVDLLNDLYTCFDTIIDK---HDVYKVETIGDAYMVVSGL--PVRNGHR- 824

Query: 491 TYDHLYQLMDFALEMQKVVDNF 512
              H  ++   AL +   + NF
Sbjct: 825 ---HAGEIATMALNLLSSMGNF 843


>SB_13681| Best HMM Match : Guanylate_cyc (HMM E-Value=2.8e-27)
          Length = 517

 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 38/117 (32%), Positives = 63/117 (53%), Gaps = 11/117 (9%)

Query: 452 FDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDN 511
           FD+ +E+     V K++TIG  +M  SGL   LR+   GT  H  ++   +L++ ++ + 
Sbjct: 356 FDDHIEK---YDVYKVETIGDAYMVVSGL--PLRN---GT-SHADEIGRMSLDLVRLTET 406

Query: 512 FNHDLFEFD--FILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVPQRI 566
              D        ++R+G + G   +GV+G     Y ++GD VN ASRM +TG+P  I
Sbjct: 407 TTLDSVPKGKKLMVRVGIHTGPCVSGVVGYKMPRYCLFGDTVNTASRMQTTGIPNVI 463


>SB_21756| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 52

 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 24/48 (50%), Positives = 35/48 (72%), Gaps = 2/48 (4%)

Query: 410 YSENHKDVAIIFASIINFNEMYDESYLK--GKEYLRILNELIADFDEL 455
           YS ++K V+++FASI NF+E Y E  +   G E +R+LNE+I DFDE+
Sbjct: 3   YSHSYKRVSVMFASIPNFSEFYSEDNINNGGVECIRLLNEVITDFDEV 50


>SB_29093| Best HMM Match : HNOBA (HMM E-Value=0)
          Length = 694

 Score = 47.2 bits (107), Expect = 4e-05
 Identities = 30/113 (26%), Positives = 61/113 (53%), Gaps = 2/113 (1%)

Query: 359 EFEISYRLSFYSNVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLK-NTAKYSENHKDV 417
           E E+  +L   SN +   + + +++ + + D LL++I+P+ VA +L+ N +  +E++K V
Sbjct: 570 ERELVEKLEETSNNLKKVESKLIEH-KKRTDDLLYSILPKEVAAKLRLNQSVPAESYKTV 628

Query: 418 AIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTI 470
            I+F+ I+ F  +     +   + +++LN L   FD L        V + +TI
Sbjct: 629 TILFSDIVGFTALCSNDKIVPMDIVKMLNRLYTYFDMLSGMNDVYKVFRSETI 681


>SB_10421| Best HMM Match : Guanylate_cyc (HMM E-Value=0)
          Length = 1485

 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 12/116 (10%)

Query: 398  RHVADQLKNTAKYS-ENHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELL 456
            R +AD+LK     S E+ + V I F+ I+ F  +  +S     + + +LN+L   FD+++
Sbjct: 969  RPIADELKKGNPVSAESFQSVTIFFSDIVGFTSVAAQS--TPLQVVDLLNQLYTRFDKVV 1026

Query: 457  ERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNF 512
            +      V K++TIG  +M  SGL   +R+  R    H  ++   AL +   V +F
Sbjct: 1027 DE---HDVYKVETIGDAYMVVSGL--PVRNGER----HAGEVASMALNLLSEVRDF 1073



 Score = 30.3 bits (65), Expect = 4.7
 Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 2/42 (4%)

Query: 565  RIQVGEACVPVLS--ARYEFEPRGSVYVKGKDDMNVYLLVGK 604
            RI V   C  VL     Y  + RG V +KGK  +  Y L GK
Sbjct: 1094 RIHVSPECKEVLDRLGGYHLDERGPVTMKGKGTIVTYFLTGK 1135


>SB_29094| Best HMM Match : Guanylate_cyc (HMM E-Value=7.9e-07)
          Length = 235

 Score = 42.3 bits (95), Expect = 0.001
 Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 2/64 (3%)

Query: 523 LRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVL--SARY 580
           +RIG + G V  GV+G     Y ++G+ V +A++M+S   P RI +      +L  ++ Y
Sbjct: 18  IRIGIHTGPVMPGVVGKKMPRYCLFGNTVTLANKMESGSQPGRINISIDTKRLLMNTSEY 77

Query: 581 EFEP 584
           +FEP
Sbjct: 78  DFEP 81


>SB_4482| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 48

 Score = 41.1 bits (92), Expect = 0.003
 Identities = 19/29 (65%), Positives = 23/29 (79%)

Query: 455 LLERPQFQHVEKIKTIGSTFMAASGLNPD 483
           +L  P+F  VEKIKTI ST+MAASGL P+
Sbjct: 1   VLADPRFLGVEKIKTISSTYMAASGLRPE 29


>SB_34632| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 320

 Score = 31.9 bits (69), Expect = 1.5
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%)

Query: 48  DQQVQSLQKLRKQSDLQLIRCVQ--DNARSGINY-FVQPPINRF-TLCF 92
           ++Q++       QS L  + CVQ  +  R   NY +++PPINRF TL F
Sbjct: 227 ERQIEIPDMAEIQSRLAYVSCVQQLEEVRESSNYEYIRPPINRFKTLDF 275


>SB_55010| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 225

 Score = 31.5 bits (68), Expect = 2.0
 Identities = 16/54 (29%), Positives = 33/54 (61%), Gaps = 4/54 (7%)

Query: 176 YLKWQTHHDPRSVAETFHDSLKIFRKLSDWYPWHLSGGLMISLPILIVLINFSC 229
           +L W+TH D  S+  + + +L + R+L +  P+H+   L+ SL  ++  +N++C
Sbjct: 49  HLSWKTHVD--SLLSSSYGTLSMLRRLKNLAPFHVRKHLVESL--VLSKLNYAC 98


>SB_24479| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 758

 Score = 31.1 bits (67), Expect = 2.7
 Identities = 26/111 (23%), Positives = 47/111 (42%), Gaps = 12/111 (10%)

Query: 397 PRHVADQLKNTAKYSENHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELL 456
           P  +A   +N  KY E   D+  +       N+    +Y +G+E+LR    L   F + +
Sbjct: 63  PEDIAKVFRNEGKYPERTADLGALQKHREKTNQPPGVAYAEGQEWLR----LRTAFGKKM 118

Query: 457 ERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQK 507
            RP        K +    +  SG+  D   + +G  D   ++ +  L++QK
Sbjct: 119 LRP--------KELAKHVVGFSGVANDAMQSIKGARDGKMEVEELELQLQK 161


>SB_53658| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 141

 Score = 29.5 bits (63), Expect = 8.2
 Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 1/51 (1%)

Query: 285 CHEVNTQYLDGDIKLYPQFLAQNLTDYFYPNDNTSDRSENNNTLNYEGMHH 335
           CH+      D  ++ Y +    N  D+   N+N +D  +NNN  N    HH
Sbjct: 71  CHDGKAGEDDKTVRRYSRENNNNNNDHHDNNNNNNDHHDNNNN-NNNNDHH 120


>SB_48470| Best HMM Match : HNOB (HMM E-Value=0)
          Length = 681

 Score = 29.5 bits (63), Expect = 8.2
 Identities = 11/30 (36%), Positives = 23/30 (76%)

Query: 376 RDKQRVQNMRNQADWLLHNIIPRHVADQLK 405
           ++ +RV+  R +++ LL+ +IP+ +AD+LK
Sbjct: 642 KNMKRVERERMRSNQLLYQMIPKQIADRLK 671


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.324    0.138    0.423 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 19,820,470
Number of Sequences: 59808
Number of extensions: 802309
Number of successful extensions: 2839
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2778
Number of HSP's gapped (non-prelim): 40
length of query: 607
length of database: 16,821,457
effective HSP length: 86
effective length of query: 521
effective length of database: 11,677,969
effective search space: 6084221849
effective search space used: 6084221849
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.5 bits)
S2: 63 (29.5 bits)

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