BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001255-TA|BGIBMGA001255-PA|IPR001054|Adenylyl cyclase class-3/4/guanylyl cyclase (607 letters) Database: nematostella 59,808 sequences; 16,821,457 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SB_51990| Best HMM Match : Guanylate_cyc (HMM E-Value=0) 263 3e-70 SB_37259| Best HMM Match : No HMM Matches (HMM E-Value=.) 99 5e-21 SB_37135| Best HMM Match : Guanylate_cyc (HMM E-Value=0) 97 5e-20 SB_11488| Best HMM Match : No HMM Matches (HMM E-Value=.) 96 8e-20 SB_10830| Best HMM Match : No HMM Matches (HMM E-Value=.) 90 5e-18 SB_43991| Best HMM Match : No HMM Matches (HMM E-Value=.) 85 2e-16 SB_50980| Best HMM Match : Guanylate_cyc (HMM E-Value=0) 80 4e-15 SB_38875| Best HMM Match : No HMM Matches (HMM E-Value=.) 79 1e-14 SB_58457| Best HMM Match : Guanylate_cyc (HMM E-Value=0) 67 4e-11 SB_58458| Best HMM Match : Guanylate_cyc (HMM E-Value=1.2e-36) 59 9e-09 SB_50731| Best HMM Match : Guanylate_cyc (HMM E-Value=0.76) 58 2e-08 SB_28889| Best HMM Match : ANF_receptor (HMM E-Value=1.1e-34) 57 5e-08 SB_13681| Best HMM Match : Guanylate_cyc (HMM E-Value=2.8e-27) 54 3e-07 SB_21756| Best HMM Match : No HMM Matches (HMM E-Value=.) 52 2e-06 SB_29093| Best HMM Match : HNOBA (HMM E-Value=0) 47 4e-05 SB_10421| Best HMM Match : Guanylate_cyc (HMM E-Value=0) 44 4e-04 SB_29094| Best HMM Match : Guanylate_cyc (HMM E-Value=7.9e-07) 42 0.001 SB_4482| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.003 SB_34632| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 1.5 SB_55010| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 2.0 SB_24479| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 2.7 SB_53658| Best HMM Match : No HMM Matches (HMM E-Value=.) 29 8.2 SB_48470| Best HMM Match : HNOB (HMM E-Value=0) 29 8.2 >SB_51990| Best HMM Match : Guanylate_cyc (HMM E-Value=0) Length = 1055 Score = 263 bits (644), Expect = 3e-70 Identities = 128/250 (51%), Positives = 177/250 (70%), Gaps = 2/250 (0%) Query: 357 NREFEISYRLSFYSNVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLKNTAKYSENHKD 416 NR+ E+ R +F + A + K++ Q + QADWLL ++ P+HV++ LK + YS N+ + Sbjct: 804 NRQLEMGVRRNFSGDAEAAKVKKKSQVHKQQADWLLLSLFPKHVSEALKTSDHYSMNYNN 863 Query: 417 VAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTI-GSTFM 475 ++FASI+NF++ Y+E++ GKE +R+LNEL+ DFDELL+ ++ VEKIKT+ GSTFM Sbjct: 864 AGVMFASIVNFSDFYEENFEGGKECIRVLNELVGDFDELLDNIEYMEVEKIKTVNGSTFM 923 Query: 476 AASGLNP-DLRHASRGTYDHLYQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDVTA 534 A +GLN D Y+HL QL++FALEM VVD FN + F F LRIG+N G VTA Sbjct: 924 AGAGLNQEDNIRREIHPYEHLKQLVEFALEMFNVVDRFNEHMLGFKFKLRIGFNAGPVTA 983 Query: 535 GVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVLSARYEFEPRGSVYVKGKD 594 GVIGTTKL YDIWGD VN+ASRMDSTGVP++IQV E+ +L+ + FE RG++ VKGK Sbjct: 984 GVIGTTKLLYDIWGDTVNLASRMDSTGVPEKIQVSESTKEMLNDFFIFERRGTIPVKGKG 1043 Query: 595 DMNVYLLVGK 604 + YL +G+ Sbjct: 1044 YVTTYLYLGR 1053 Score = 100 bits (240), Expect = 3e-21 Identities = 57/193 (29%), Positives = 102/193 (52%), Gaps = 14/193 (7%) Query: 415 KDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTF 474 ++V+I+FA I+ F +M S + +R+LN+L FD L E + H EKI T+G + Sbjct: 306 ENVSILFADIVGFTKM--SSNKSADQLVRLLNDLFGRFDRLTE---YNHCEKISTLGDCY 360 Query: 475 MAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDVTA 534 +G + T +H ++ L+M + + F++D + D +R+G + G V Sbjct: 361 YCVAG-------CPKPTPNHATYCVEMGLDMLEQIKEFDNDT-DNDVDMRVGVHTGTVLC 412 Query: 535 GVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVLSARYEFE-PRGSVYVKGK 593 G++GT + +D+W + V +A+RM++ G+P R+ + EA V L +Y E G Sbjct: 413 GIVGTKRFKFDVWSNDVTLANRMETAGLPGRVHITEATVGFLRDQYIVENGHGETRNAAL 472 Query: 594 DDMNVYLLVGKKD 606 + Y +VG+K+ Sbjct: 473 KGITTYFIVGRKN 485 Score = 40.3 bits (90), Expect = 0.004 Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 2/91 (2%) Query: 55 QKLRKQSDLQLIRCVQDNARSGINYFVQPPINRFTLCFESDEMERHYRDKAHRSDDCEDL 114 + LR +D QL+ + + G YF P++ TL F E+E+ Y+++ S Sbjct: 614 ETLRTSNDQQLVHLMSEQG-VGDEYF-HAPVSTCTLQFYDKELEQQYQNEGQDSTLLNPS 671 Query: 115 PPTLTTSRFNTALDILVSALIFLAVSASAFV 145 T + + N D+L+S ++F + F+ Sbjct: 672 VTTFASPKVNFFTDVLLSNIVFFTICVLCFL 702 Score = 37.9 bits (84), Expect = 0.023 Identities = 11/40 (27%), Positives = 27/40 (67%) Query: 241 QSFYVYLLCISIVHFCNFTQMNWLAKNTLVTLYAGVFLFV 280 ++F+ Y++ ++++HFCNFTQ+ K +L ++ ++ + Sbjct: 726 RNFFSYIVAVALLHFCNFTQLTSWMKTSLAAVFTMTYIIL 765 >SB_37259| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1690 Score = 99 bits (238), Expect = 5e-21 Identities = 73/256 (28%), Positives = 134/256 (52%), Gaps = 23/256 (8%) Query: 357 NREFEISYRLSFYSNVVANRDKQR---VQNMRNQADWLLHNIIPRHVADQLK-NTAKYSE 412 + +F+ Y L+ ++ ++ +Q + + D LL++++P VA++L+ N +E Sbjct: 1401 SEQFKAEYVLTQQLEILTDKLRQTHNALAEKKQLTDQLLYSVLPPSVANELRHNRPVQAE 1460 Query: 413 NHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGS 472 + V ++F+ I++F ++ S K E + +LN + FD L + P V K++T+G Sbjct: 1461 RAEMVTLLFSGIVDFAQICKNS--KPMEIVMLLNNIYTKFDMLTD-PSINDVYKVETVGD 1517 Query: 473 TFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDV 532 +MA SGL P+ R + H + + AL+M+ V + H + ++IG + G+V Sbjct: 1518 KYMAVSGL-PE-----RCAF-HARSICNMALDMKHVTQSIIHKGDKIQ--IKIGIHSGEV 1568 Query: 533 TAGVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVL------SARYEFEPRG 586 AGV+G Y ++G+ VN+ SR ++TG P ++ + E L + FE RG Sbjct: 1569 VAGVVGHKTPRYCLFGNTVNLTSRTETTGAPGQVNITEFTYRCLLEPECQDPSFVFERRG 1628 Query: 587 SVYVKGKDD-MNVYLL 601 V +KG+ + M YLL Sbjct: 1629 PVAMKGRQEPMVTYLL 1644 Score = 92.3 bits (219), Expect = 1e-18 Identities = 70/248 (28%), Positives = 124/248 (50%), Gaps = 16/248 (6%) Query: 357 NREFEISYRLSFYSNVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLKNTAKYSEN-HK 415 N EF++S RL ++ + ++ ++N + D LL++I+P VA+ L+ + N ++ Sbjct: 857 NAEFKLSQRLEILTDKLQQTSRE-LENEQQLNDRLLYSILPASVANDLRLRKPVNANKYE 915 Query: 416 DVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFM 475 V I+F+ I++F Y + E + +LNE+ +FD+L + + K++T+G +M Sbjct: 916 IVTIMFSGIVDFTN-YCNKIKEPMEIVEMLNEVYTEFDQLTDSND--DIYKVETVGDKYM 972 Query: 476 AASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDVTAG 535 A SGL H + + AL+M + + + IG + G+V AG Sbjct: 973 AVSGLPTRCDK-------HALNIANLALDMIDISKGMKAKGIQLQ--VTIGIHSGEVVAG 1023 Query: 536 VIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVLSARYEFEPRGSVYVKGKDD 595 V+G K Y ++G+ VN+ SR ++TG+ +I V E +A E E + DD Sbjct: 1024 VVGQKKPRYCLFGNTVNLTSRTETTGLKGKINVSEYAYR-RAAELEIEGHFLQRII-YDD 1081 Query: 596 MNVYLLVG 603 + Y LVG Sbjct: 1082 VMTYSLVG 1089 Score = 59.7 bits (138), Expect = 7e-09 Identities = 48/191 (25%), Positives = 90/191 (47%), Gaps = 16/191 (8%) Query: 381 VQNMRNQADWLLHNIIPRHVADQLKNTAKYSENH-KDVAIIFASIINFNEMYDESYLKGK 439 ++ + + + LL +I P VA++L N H ++V ++F+ I+ F + + Sbjct: 423 LEEEKKKTENLLSSIFPHDVANKLINKQPIPARHIQNVTMLFSDIVGFTAICGKC--SAM 480 Query: 440 EYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLM 499 + + +L L FD+L K++TIG ++ A G+ H GT + Y + Sbjct: 481 DVVEMLKSLYTKFDKLCGELDLY---KVETIGDAYVVAGGVQ---NHC--GTAEDAYHVA 532 Query: 500 DFALEMQKVVDNFNHDLFE--FDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRM 557 A+ M +D+ L +R+G + G V +GV+GT Y ++G V +A++M Sbjct: 533 LMAVGM---IDHIRDVLSPEGVPLKMRVGIHTGSVLSGVVGTKMPRYCLFGHDVTLANKM 589 Query: 558 DSTGVPQRIQV 568 +S RI + Sbjct: 590 ESESEAGRINI 600 >SB_37135| Best HMM Match : Guanylate_cyc (HMM E-Value=0) Length = 584 Score = 96.7 bits (230), Expect = 5e-20 Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 17/218 (7%) Query: 379 QRVQNMRNQADWLLHNIIPRHVADQLKN---TAKYSENHKDVAIIFASIINFNEMYDESY 435 + + N + + D LL+ +IP+ VAD+L+ E +V I+F+ ++ F + S Sbjct: 372 RELDNEKLRTDALLYQMIPKTVADRLRKGEPALNTCETFSNVTILFSDVVGFTTIC--SL 429 Query: 436 LKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHL 495 + + + +LN + FD+L E+ +V K++TIG +M SG+ P+ R Y H Sbjct: 430 IAPMQVVTMLNCMYTTFDKLSEK---HNVYKVETIGDAYMVVSGI-PE-----RTKY-HA 479 Query: 496 YQLMDFALEMQKVVDNFNHDLFEFDFI-LRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIA 554 + D AL M + D + +RIG + G V AGV+G Y ++GD VN A Sbjct: 480 EHVADMALNMLSAMPEIEDPAGLNDHLRIRIGIHTGTVVAGVVGLKMPRYCLFGDTVNTA 539 Query: 555 SRMDSTGVPQRIQVGEACVPVLS-ARYEFEPRGSVYVK 591 SRM+STG+ I V E L+ A Y + RGS+ +K Sbjct: 540 SRMESTGLAMAIHVSEDTQKFLAKANYALKQRGSMDIK 577 >SB_11488| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 250 Score = 95.9 bits (228), Expect = 8e-20 Identities = 65/235 (27%), Positives = 125/235 (53%), Gaps = 16/235 (6%) Query: 371 NVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLK-NTAKYSENHKDVAIIFASIINFNE 429 ++V R +Q ++ +++ D LL+ ++PR +ADQLK +E+ +V + + I++F Sbjct: 22 SLVKERTRQ-LETEKSKTDELLYRMLPRLIADQLKAGLPLKAESFSEVTVFYCDIVDFTV 80 Query: 430 MYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASR 489 + S + + +++LN++ + FD ++ R + K++T+G + + SGL P+ R+ +R Sbjct: 81 ITALS--EPMQVIKLLNDVYSLFDTIMGR---YDIYKVETVGDSCLVVSGL-PE-RNGNR 133 Query: 490 GTYDHLYQLMDFALEMQKVVDNFNHD-LFEFDFILRIGYNFGDVTAGVIGTTKLYYDIWG 548 H ++ +L + V +F + L + R+G + G AG++G K YDI+G Sbjct: 134 ----HASEIAAMSLHLLNYVTDFRIEHLPDTRLEFRMGIHTGPCVAGIVGLKKPRYDIFG 189 Query: 549 DAVNIASRMDSTGVPQRIQVGEACVPVLS--ARYEFEPRGSVYVKGKDDMNVYLL 601 + VNI ++S G+PQ I V +L+ + E RG + +KG Y L Sbjct: 190 ETVNIVKHLESAGIPQSIHVSSPTCRLLTTLGGFMLETRGEMLIKGIGITTTYFL 244 >SB_10830| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1006 Score = 89.8 bits (213), Expect = 5e-18 Identities = 53/115 (46%), Positives = 65/115 (56%), Gaps = 4/115 (3%) Query: 492 YDHLYQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAV 551 + Y +D E + + N L +FD + NFG V AGVIG K YDIWGD V Sbjct: 887 FSDFYTELDANGEGVECLRLLNEILADFD---EVSLNFGPVVAGVIGAHKPQYDIWGDTV 943 Query: 552 NIASRMDSTGVPQRIQVGEACVPVLSAR-YEFEPRGSVYVKGKDDMNVYLLVGKK 605 N+ASRM STG IQV +A +LS R Y F+ RG V VKGK M Y L+GK+ Sbjct: 944 NVASRMYSTGKDNHIQVTKAMYEILSTRGYTFDCRGLVAVKGKGKMVTYWLLGKE 998 Score = 65.7 bits (153), Expect = 1e-10 Identities = 37/99 (37%), Positives = 58/99 (58%), Gaps = 8/99 (8%) Query: 365 RLSFYSNVVANRDKQRVQNMRNQADWLLHNIIPRHVADQL------KNTAKYSENHKDVA 418 RL F + A +K+ ++ +R LL+NI+P HVA KN Y ++ VA Sbjct: 819 RLDFLWKLQATEEKKEMEQLREYNKKLLYNILPVHVAQHFLGHKANKNEDLYYQSCDKVA 878 Query: 419 IIFASIINFNEMYDESYLKGK--EYLRILNELIADFDEL 455 ++F++I NF++ Y E G+ E LR+LNE++ADFDE+ Sbjct: 879 VMFSNICNFSDFYTELDANGEGVECLRLLNEILADFDEV 917 Score = 64.1 bits (149), Expect = 3e-10 Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 8/104 (7%) Query: 460 QFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNFNHDLFEF 519 Q H +IK +G + SGL PD R DH + ++ L M + +F D + Sbjct: 498 QENHCLRIKILGDCYYCVSGL-PDPRP------DHAHSCIEMGLAMIDAI-SFVRDATQV 549 Query: 520 DFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVP 563 + +R+G + G V +GV+G K YD+W D V IA+ M+S G+P Sbjct: 550 NLNMRVGVHMGKVHSGVLGLVKWQYDVWSDDVTIANHMESGGLP 593 Score = 41.5 bits (93), Expect = 0.002 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 14/107 (13%) Query: 361 EISYRLSFYSNVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLKNTAK----------- 409 EIS R +F + +Q + LL +++PR+VA ++K+ + Sbjct: 349 EISQRQAFLETRRCIEARLTIQKENQNQERLLLSVLPRYVAMEMKDDIESGISQNSQFHK 408 Query: 410 -YSENHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDEL 455 Y + H++V+I+FA I F + S + ++ LNEL A FD+L Sbjct: 409 IYIQRHENVSILFADIEGFTVL--SSQCTAQSLIKTLNELYARFDQL 453 >SB_43991| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1149 Score = 84.6 bits (200), Expect = 2e-16 Identities = 61/173 (35%), Positives = 93/173 (53%), Gaps = 20/173 (11%) Query: 395 IIPRHVADQLKN-TAKYSENHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFD 453 II + VA+QLK A +E+ +V I F+ I+ F + ES + + LN+L FD Sbjct: 856 IIIKPVAEQLKKGKAVEAESFNEVTIYFSDIVGFTSLSAES--TPMQVVTFLNDLYTIFD 913 Query: 454 ELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNFN 513 ++++ V K++TIG +M ASGL +R+ R H ++ AL + VD + Sbjct: 914 DIIQE---YDVYKVETIGDAYMVASGL--PIRNGRR----HAGEIAKMALHL---VDAVS 961 Query: 514 HDLF-----EFDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTG 561 H+ E+ LR+G + G V AGV+G T Y ++GD VN ASRM+S G Sbjct: 962 HNFIVRHKPEYKLQLRVGCHTGPVVAGVVGNTMARYCLFGDTVNTASRMESNG 1014 >SB_50980| Best HMM Match : Guanylate_cyc (HMM E-Value=0) Length = 313 Score = 80.2 bits (189), Expect = 4e-15 Identities = 58/169 (34%), Positives = 89/169 (52%), Gaps = 16/169 (9%) Query: 397 PRHVADQLKN-TAKYSENHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDEL 455 P VA+QLK A +E+ +V+I F+ I+ F + ES + + +LN+L FD++ Sbjct: 154 PGSVAEQLKKGKAVEAESFDEVSIYFSDIVGFTSLSAES--TPMQVVTLLNDLYTLFDDI 211 Query: 456 LERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDN---F 512 + V K++TIG +M SGL +R+ SR H ++ +L + V Sbjct: 212 IRE---YDVYKVETIGDAYMVVSGL--PIRNGSR----HAGEIARMSLHLVDAVQTEFCV 262 Query: 513 NHDLFEFDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTG 561 H E+ LR+G + G V AGV+G T Y ++GD VN ASRM+S G Sbjct: 263 RHKP-EYKLKLRVGIHSGPVVAGVVGNTMPRYCLFGDTVNTASRMESNG 310 >SB_38875| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1116 Score = 78.6 bits (185), Expect = 1e-14 Identities = 55/208 (26%), Positives = 100/208 (48%), Gaps = 28/208 (13%) Query: 391 LLHNIIPRHVADQLK-------------NTAK--YSENHKDVAIIFASIINFNEMYDESY 435 LL +++P+HVA+++ N K + H +I+FA I+ F E+ S Sbjct: 484 LLLSVLPKHVAEEMTKDFEGDGNPALTDNAFKKLFIRTHDTCSILFADIVGFTEL--SSK 541 Query: 436 LKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHL 495 ++ + LNEL A+FD+L + H +IK +G + SGL+ HA Sbjct: 542 CTAEQLIVTLNELFANFDKLAAK---NHCLRIKILGDCYYCISGLDDSCNHALCA----- 593 Query: 496 YQLMDFALEMQKVVDNFNHDLFEFDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIAS 555 ++ L+M + + + + +R+G + G V AGV+G K ++ W + V +A+ Sbjct: 594 ---VNMGLDMVEHIAHVREEKGVKSLNMRVGIHTGMVLAGVLGQRKWQFEAWSNDVTLAN 650 Query: 556 RMDSTGVPQRIQVGEACVPVLSARYEFE 583 M+S G+P R+ + E + + +E E Sbjct: 651 HMESGGIPGRVHISEPTLNSIKDYFEVE 678 Score = 70.9 bits (166), Expect = 3e-12 Identities = 35/79 (44%), Positives = 49/79 (62%), Gaps = 1/79 (1%) Query: 530 GDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQV-GEACVPVLSARYEFEPRGSV 588 G + AGVIG K +YDIWG+ VN+ASRM++TG IQ+ + + + F RG+V Sbjct: 1028 GPIVAGVIGAKKPHYDIWGNTVNVASRMETTGKAGCIQITAQTYETIKDKDFVFVYRGAV 1087 Query: 589 YVKGKDDMNVYLLVGKKDT 607 VKGK + Y L G+K+T Sbjct: 1088 RVKGKGQLITYYLTGRKNT 1106 >SB_58457| Best HMM Match : Guanylate_cyc (HMM E-Value=0) Length = 410 Score = 66.9 bits (156), Expect = 4e-11 Identities = 64/225 (28%), Positives = 107/225 (47%), Gaps = 33/225 (14%) Query: 385 RNQADWLLHNIIPRHVADQLK-NTAKYSENHKDVAIIFASIINFNEMYDESYLKGKEYLR 443 + + D LL ++P+ V DQLK + +E+ +V+I F+ I+ F E+ ES + + Sbjct: 96 KKKTDALLERMLPKPVTDQLKRGKSVEAESFHEVSIYFSDIVGFTELSAES--SPLQVVS 153 Query: 444 ILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFAL 503 +LN+L FD+++ V K++TIG +M SGL +R+ +R H ++ AL Sbjct: 154 LLNDLYTLFDDIIRE---YDVYKVETIGDAYMVVSGL--PIRNGNR----HAGEIAKMAL 204 Query: 504 EMQKVVDNFNHDLFEFDFILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVP 563 + + V + +FI+R + KL I D + + M + Sbjct: 205 HLIEAV--------QTEFIVRYKPTY---------KLKLRVGIHSDLIVLI--MIVFSIA 245 Query: 564 QRIQVGEACVPVLS--ARYEFEPRGSVYVKGKDDMNVYLLVGKKD 606 RI + E +L + E RG VY+KGK +M+ Y LV KD Sbjct: 246 LRIHISEDTKRILDQLGGFVVEGRGEVYLKGKGNMHTYWLVDIKD 290 >SB_58458| Best HMM Match : Guanylate_cyc (HMM E-Value=1.2e-36) Length = 1065 Score = 59.3 bits (137), Expect = 9e-09 Identities = 49/167 (29%), Positives = 81/167 (48%), Gaps = 14/167 (8%) Query: 371 NVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLKNTAKYS-ENHKDVAIIFASIINFNE 429 ++V R Q R + LL+ ++P VA L + + + EN +V+I F+ I+ F Sbjct: 710 SLVEERTSQLADEKRKTEN-LLNRMLPPSVAKDLVHGKQVTAENFDEVSIFFSDIVGFTS 768 Query: 430 MYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASR 489 + ES + + +LN+L FDE++ V K++TIG +M SGL R Sbjct: 769 LSSES--TPLQVVDLLNDLYTLFDEIINN---YDVYKVETIGDAYMVVSGL------PIR 817 Query: 490 GTYDHLYQLMDFALEMQKVVDNFNHDLFEFDFI-LRIGYNFGDVTAG 535 + H ++ AL M + +D+F D + LRIG + G V +G Sbjct: 818 NGHQHAGEIATMALHMLREIDSFKIRHRPNDKLKLRIGIHSGMVVSG 864 >SB_50731| Best HMM Match : Guanylate_cyc (HMM E-Value=0.76) Length = 64 Score = 58.0 bits (134), Expect = 2e-08 Identities = 28/60 (46%), Positives = 36/60 (60%), Gaps = 2/60 (3%) Query: 534 AGVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVL--SARYEFEPRGSVYVK 591 AGV+G K YD++GD VN+ASRM+S GVP RI + C L Y E RG + +K Sbjct: 5 AGVVGIKKPRYDVFGDTVNVASRMESNGVPNRIHISAECRKALLNLGGYHMERRGEIELK 64 >SB_28889| Best HMM Match : ANF_receptor (HMM E-Value=1.1e-34) Length = 933 Score = 56.8 bits (131), Expect = 5e-08 Identities = 40/142 (28%), Positives = 75/142 (52%), Gaps = 13/142 (9%) Query: 372 VVANRDKQRVQNMRNQADWLLHNIIPRHVADQLKNTAKY-SENHKDVAIIFASIINFNEM 430 +V R +Q + + + + D LL+ ++PR++A+ LK +E++ V I F+ I+ F E+ Sbjct: 714 IVDERTRQ-LADEKAKTDELLYKMLPRYIAESLKRGEPVIAESYSSVTIFFSDIVGFTEL 772 Query: 431 YDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRG 490 S + + +LN+L FD ++++ V K++TIG +M SGL +R+ R Sbjct: 773 AAAS--TPLQVVDLLNDLYTCFDTIIDK---HDVYKVETIGDAYMVVSGL--PVRNGHR- 824 Query: 491 TYDHLYQLMDFALEMQKVVDNF 512 H ++ AL + + NF Sbjct: 825 ---HAGEIATMALNLLSSMGNF 843 >SB_13681| Best HMM Match : Guanylate_cyc (HMM E-Value=2.8e-27) Length = 517 Score = 54.4 bits (125), Expect = 3e-07 Identities = 38/117 (32%), Positives = 63/117 (53%), Gaps = 11/117 (9%) Query: 452 FDELLERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDN 511 FD+ +E+ V K++TIG +M SGL LR+ GT H ++ +L++ ++ + Sbjct: 356 FDDHIEK---YDVYKVETIGDAYMVVSGL--PLRN---GT-SHADEIGRMSLDLVRLTET 406 Query: 512 FNHDLFEFD--FILRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVPQRI 566 D ++R+G + G +GV+G Y ++GD VN ASRM +TG+P I Sbjct: 407 TTLDSVPKGKKLMVRVGIHTGPCVSGVVGYKMPRYCLFGDTVNTASRMQTTGIPNVI 463 >SB_21756| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 52 Score = 51.6 bits (118), Expect = 2e-06 Identities = 24/48 (50%), Positives = 35/48 (72%), Gaps = 2/48 (4%) Query: 410 YSENHKDVAIIFASIINFNEMYDESYLK--GKEYLRILNELIADFDEL 455 YS ++K V+++FASI NF+E Y E + G E +R+LNE+I DFDE+ Sbjct: 3 YSHSYKRVSVMFASIPNFSEFYSEDNINNGGVECIRLLNEVITDFDEV 50 >SB_29093| Best HMM Match : HNOBA (HMM E-Value=0) Length = 694 Score = 47.2 bits (107), Expect = 4e-05 Identities = 30/113 (26%), Positives = 61/113 (53%), Gaps = 2/113 (1%) Query: 359 EFEISYRLSFYSNVVANRDKQRVQNMRNQADWLLHNIIPRHVADQLK-NTAKYSENHKDV 417 E E+ +L SN + + + +++ + + D LL++I+P+ VA +L+ N + +E++K V Sbjct: 570 ERELVEKLEETSNNLKKVESKLIEH-KKRTDDLLYSILPKEVAAKLRLNQSVPAESYKTV 628 Query: 418 AIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELLERPQFQHVEKIKTI 470 I+F+ I+ F + + + +++LN L FD L V + +TI Sbjct: 629 TILFSDIVGFTALCSNDKIVPMDIVKMLNRLYTYFDMLSGMNDVYKVFRSETI 681 >SB_10421| Best HMM Match : Guanylate_cyc (HMM E-Value=0) Length = 1485 Score = 44.0 bits (99), Expect = 4e-04 Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 12/116 (10%) Query: 398 RHVADQLKNTAKYS-ENHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELL 456 R +AD+LK S E+ + V I F+ I+ F + +S + + +LN+L FD+++ Sbjct: 969 RPIADELKKGNPVSAESFQSVTIFFSDIVGFTSVAAQS--TPLQVVDLLNQLYTRFDKVV 1026 Query: 457 ERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQKVVDNF 512 + V K++TIG +M SGL +R+ R H ++ AL + V +F Sbjct: 1027 DE---HDVYKVETIGDAYMVVSGL--PVRNGER----HAGEVASMALNLLSEVRDF 1073 Score = 30.3 bits (65), Expect = 4.7 Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 2/42 (4%) Query: 565 RIQVGEACVPVLS--ARYEFEPRGSVYVKGKDDMNVYLLVGK 604 RI V C VL Y + RG V +KGK + Y L GK Sbjct: 1094 RIHVSPECKEVLDRLGGYHLDERGPVTMKGKGTIVTYFLTGK 1135 >SB_29094| Best HMM Match : Guanylate_cyc (HMM E-Value=7.9e-07) Length = 235 Score = 42.3 bits (95), Expect = 0.001 Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Query: 523 LRIGYNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVPQRIQVGEACVPVL--SARY 580 +RIG + G V GV+G Y ++G+ V +A++M+S P RI + +L ++ Y Sbjct: 18 IRIGIHTGPVMPGVVGKKMPRYCLFGNTVTLANKMESGSQPGRINISIDTKRLLMNTSEY 77 Query: 581 EFEP 584 +FEP Sbjct: 78 DFEP 81 >SB_4482| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 48 Score = 41.1 bits (92), Expect = 0.003 Identities = 19/29 (65%), Positives = 23/29 (79%) Query: 455 LLERPQFQHVEKIKTIGSTFMAASGLNPD 483 +L P+F VEKIKTI ST+MAASGL P+ Sbjct: 1 VLADPRFLGVEKIKTISSTYMAASGLRPE 29 >SB_34632| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 320 Score = 31.9 bits (69), Expect = 1.5 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%) Query: 48 DQQVQSLQKLRKQSDLQLIRCVQ--DNARSGINY-FVQPPINRF-TLCF 92 ++Q++ QS L + CVQ + R NY +++PPINRF TL F Sbjct: 227 ERQIEIPDMAEIQSRLAYVSCVQQLEEVRESSNYEYIRPPINRFKTLDF 275 >SB_55010| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 225 Score = 31.5 bits (68), Expect = 2.0 Identities = 16/54 (29%), Positives = 33/54 (61%), Gaps = 4/54 (7%) Query: 176 YLKWQTHHDPRSVAETFHDSLKIFRKLSDWYPWHLSGGLMISLPILIVLINFSC 229 +L W+TH D S+ + + +L + R+L + P+H+ L+ SL ++ +N++C Sbjct: 49 HLSWKTHVD--SLLSSSYGTLSMLRRLKNLAPFHVRKHLVESL--VLSKLNYAC 98 >SB_24479| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 758 Score = 31.1 bits (67), Expect = 2.7 Identities = 26/111 (23%), Positives = 47/111 (42%), Gaps = 12/111 (10%) Query: 397 PRHVADQLKNTAKYSENHKDVAIIFASIINFNEMYDESYLKGKEYLRILNELIADFDELL 456 P +A +N KY E D+ + N+ +Y +G+E+LR L F + + Sbjct: 63 PEDIAKVFRNEGKYPERTADLGALQKHREKTNQPPGVAYAEGQEWLR----LRTAFGKKM 118 Query: 457 ERPQFQHVEKIKTIGSTFMAASGLNPDLRHASRGTYDHLYQLMDFALEMQK 507 RP K + + SG+ D + +G D ++ + L++QK Sbjct: 119 LRP--------KELAKHVVGFSGVANDAMQSIKGARDGKMEVEELELQLQK 161 >SB_53658| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 141 Score = 29.5 bits (63), Expect = 8.2 Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 1/51 (1%) Query: 285 CHEVNTQYLDGDIKLYPQFLAQNLTDYFYPNDNTSDRSENNNTLNYEGMHH 335 CH+ D ++ Y + N D+ N+N +D +NNN N HH Sbjct: 71 CHDGKAGEDDKTVRRYSRENNNNNNDHHDNNNNNNDHHDNNNN-NNNNDHH 120 >SB_48470| Best HMM Match : HNOB (HMM E-Value=0) Length = 681 Score = 29.5 bits (63), Expect = 8.2 Identities = 11/30 (36%), Positives = 23/30 (76%) Query: 376 RDKQRVQNMRNQADWLLHNIIPRHVADQLK 405 ++ +RV+ R +++ LL+ +IP+ +AD+LK Sbjct: 642 KNMKRVERERMRSNQLLYQMIPKQIADRLK 671 Database: nematostella Posted date: Oct 22, 2007 1:22 PM Number of letters in database: 16,821,457 Number of sequences in database: 59,808 Lambda K H 0.324 0.138 0.423 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 19,820,470 Number of Sequences: 59808 Number of extensions: 802309 Number of successful extensions: 2839 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 17 Number of HSP's successfully gapped in prelim test: 6 Number of HSP's that attempted gapping in prelim test: 2778 Number of HSP's gapped (non-prelim): 40 length of query: 607 length of database: 16,821,457 effective HSP length: 86 effective length of query: 521 effective length of database: 11,677,969 effective search space: 6084221849 effective search space used: 6084221849 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 40 (21.5 bits) S2: 63 (29.5 bits)
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