Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001254-TA|BGIBMGA001254-PA|IPR001054|Adenylyl cyclase
class-3/4/guanylyl cyclase
(705 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B5E7D Cluster: PREDICTED: similar to adenylate ... 314 5e-84
UniRef50_UPI0000D55CA0 Cluster: PREDICTED: similar to CG9210-PA,... 291 6e-77
UniRef50_Q7QEP6 Cluster: ENSANGP00000019838; n=3; Bilateria|Rep:... 271 5e-71
UniRef50_O16039 Cluster: Adenylyl cyclase isoform DAC9; n=4; Sop... 255 3e-66
UniRef50_O60503 Cluster: Adenylate cyclase type 9; n=29; Euteleo... 170 1e-40
UniRef50_A7RN58 Cluster: Predicted protein; n=2; Nematostella ve... 165 4e-39
UniRef50_Q19523 Cluster: Putative uncharacterized protein acy-1;... 162 3e-38
UniRef50_UPI0000E49494 Cluster: PREDICTED: similar to adenylyl c... 140 9e-32
UniRef50_Q5BXY8 Cluster: SJCHGC07735 protein; n=1; Schistosoma j... 119 2e-25
UniRef50_Q4RZV3 Cluster: Chromosome 18 SCAF14786, whole genome s... 110 1e-22
UniRef50_Q4T7J2 Cluster: Chromosome undetermined SCAF8089, whole... 105 4e-21
UniRef50_Q6WIQ8 Cluster: Adenylate cyclase type VII; n=2; Xenopu... 104 7e-21
UniRef50_Q966F9 Cluster: Adenylyl cyclase protein 4; n=2; Caenor... 103 2e-20
UniRef50_Q5MAL2 Cluster: Adenylate cyclase; n=1; Aplysia califor... 102 3e-20
UniRef50_Q9VW60 Cluster: Adenylate cyclase type 2; n=2; Sophopho... 102 3e-20
UniRef50_Q4RVX9 Cluster: Chromosome 9 SCAF14991, whole genome sh... 102 4e-20
UniRef50_UPI0000D5745B Cluster: PREDICTED: similar to CG32158-PB... 101 5e-20
UniRef50_UPI00015A564B Cluster: Novel protein similar to vertebr... 101 5e-20
UniRef50_UPI000155CC3E Cluster: PREDICTED: similar to adenylate ... 101 9e-20
UniRef50_Q5TUN5 Cluster: ENSANGP00000027378; n=2; Culicidae|Rep:... 101 9e-20
UniRef50_Q4T405 Cluster: Chromosome 8 SCAF9864, whole genome sho... 100 2e-19
UniRef50_O95622 Cluster: Adenylate cyclase type 5; n=41; Deutero... 100 3e-19
UniRef50_O96306 Cluster: Adenylyl cyclase isoform DAC39E; n=7; D... 99 4e-19
UniRef50_Q6PG12 Cluster: Adcy3 protein; n=13; Euteleostomi|Rep: ... 99 5e-19
UniRef50_Q5MAL1 Cluster: Adenylate cyclase; n=1; Aplysia califor... 99 5e-19
UniRef50_P32870 Cluster: Ca(2+)/calmodulin-responsive adenylate ... 99 5e-19
UniRef50_O60266 Cluster: Adenylate cyclase type 3; n=21; Theria|... 99 5e-19
UniRef50_UPI000155DD86 Cluster: PREDICTED: similar to adenylate ... 98 8e-19
UniRef50_Q4STI6 Cluster: Chromosome undetermined SCAF14199, whol... 97 1e-18
UniRef50_UPI00005A2FB4 Cluster: PREDICTED: similar to brain aden... 97 1e-18
UniRef50_Q16XH3 Cluster: Adenylate cyclase; n=3; Endopterygota|R... 97 1e-18
UniRef50_Q8NFM4 Cluster: Adenylate cyclase type 4; n=73; Euteleo... 97 1e-18
UniRef50_Q4SUW5 Cluster: Chromosome undetermined SCAF13838, whol... 97 2e-18
UniRef50_UPI0000E47CE1 Cluster: PREDICTED: similar to Adenylate ... 96 3e-18
UniRef50_UPI0000DB73AC Cluster: PREDICTED: similar to Adenylyl c... 96 3e-18
UniRef50_UPI000069E67B Cluster: Adenylate cyclase type 1 (EC 4.6... 96 3e-18
UniRef50_UPI000069E679 Cluster: Adenylate cyclase type 1 (EC 4.6... 96 3e-18
UniRef50_UPI000065D458 Cluster: Adenylate cyclase type 3 (EC 4.6... 96 3e-18
UniRef50_Q9VV68 Cluster: CG32158-PB, isoform B; n=12; Coelomata|... 96 3e-18
UniRef50_O16880 Cluster: Adenylyl cyclase protein 2; n=2; Caenor... 96 3e-18
UniRef50_Q7QDV4 Cluster: ENSANGP00000010056; n=1; Anopheles gamb... 95 4e-18
UniRef50_UPI00015B5F6F Cluster: PREDICTED: similar to ENSANGP000... 95 6e-18
UniRef50_Q9Y1V0 Cluster: Adenylyl cyclase 78C-L; n=4; Sophophora... 95 6e-18
UniRef50_P40145 Cluster: Adenylate cyclase type 8 (EC 4.6.1.1) (... 95 6e-18
UniRef50_UPI0000DB7A4D Cluster: PREDICTED: similar to Adenylyl c... 95 8e-18
UniRef50_UPI0000D56083 Cluster: PREDICTED: similar to CG10564-PA... 95 8e-18
UniRef50_Q08828 Cluster: Adenylate cyclase type 1 (EC 4.6.1.1) (... 95 8e-18
UniRef50_Q4S9A3 Cluster: Chromosome undetermined SCAF14699, whol... 94 1e-17
UniRef50_Q0C7B2 Cluster: Adenylate cyclase; n=2; Culicidae|Rep: ... 94 1e-17
UniRef50_UPI00015A6AA9 Cluster: Adenylate cyclase type 8 (EC 4.6... 93 2e-17
UniRef50_A7S0C5 Cluster: Predicted protein; n=1; Nematostella ve... 93 2e-17
UniRef50_Q4SNI3 Cluster: Chromosome 15 SCAF14542, whole genome s... 93 3e-17
UniRef50_Q1MU16 Cluster: ORF for hypothetical protein; n=2; Apoc... 93 3e-17
UniRef50_UPI000065E155 Cluster: Adenylate cyclase type 8 (EC 4.6... 92 4e-17
UniRef50_Q9W037 Cluster: CG32301-PA; n=1; Drosophila melanogaste... 91 9e-17
UniRef50_Q8IGU9 Cluster: RE26442p; n=4; Sophophora|Rep: RE26442p... 91 9e-17
UniRef50_Q17AS9 Cluster: Adenylate cyclase; n=2; Culicidae|Rep: ... 89 3e-16
UniRef50_Q5MAL0 Cluster: Adenylate cyclase; n=2; Eukaryota|Rep: ... 87 1e-15
UniRef50_A7RRQ7 Cluster: Predicted protein; n=1; Nematostella ve... 87 2e-15
UniRef50_UPI0000D56082 Cluster: PREDICTED: similar to adenylate ... 86 4e-15
UniRef50_UPI00005A96A3 Cluster: PREDICTED: similar to adenylate ... 85 5e-15
UniRef50_Q8IRF5 Cluster: CG32305-PA; n=2; Sophophora|Rep: CG3230... 85 5e-15
UniRef50_Q4RR06 Cluster: Chromosome 14 SCAF15003, whole genome s... 85 6e-15
UniRef50_Q9VK53 Cluster: CG5983-PA, isoform A; n=13; Sophophora|... 85 6e-15
UniRef50_UPI0000DB7252 Cluster: PREDICTED: similar to ACXD CG571... 84 1e-14
UniRef50_UPI00015B5520 Cluster: PREDICTED: similar to adenylate ... 83 2e-14
UniRef50_A0YU66 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC... 83 3e-14
UniRef50_UPI00006CB3C2 Cluster: Adenylate and Guanylate cyclase ... 80 2e-13
UniRef50_A5P0P3 Cluster: Response regulator receiver protein; n=... 78 7e-13
UniRef50_A0C5Y1 Cluster: Chromosome undetermined scaffold_151, w... 78 7e-13
UniRef50_Q23TD7 Cluster: Adenylate and Guanylate cyclase catalyt... 78 9e-13
UniRef50_UPI00006CB738 Cluster: Adenylate and Guanylate cyclase ... 77 1e-12
UniRef50_Q8YZ26 Cluster: Adenylate cyclase; n=1; Nostoc sp. PCC ... 77 2e-12
UniRef50_A0BG69 Cluster: Chromosome undetermined scaffold_105, w... 77 2e-12
UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein... 76 3e-12
UniRef50_A0YIQ8 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC... 76 3e-12
UniRef50_A0DTD8 Cluster: Chromosome undetermined scaffold_63, wh... 76 3e-12
UniRef50_Q7WWV9 Cluster: Putative regulatory protein; n=1; Ralst... 76 4e-12
UniRef50_A0CKZ5 Cluster: Chromosome undetermined scaffold_20, wh... 75 5e-12
UniRef50_Q8F690 Cluster: Adenylate cyclase; n=4; Leptospira|Rep:... 75 7e-12
UniRef50_Q394B3 Cluster: Adenylate/guanylate cyclase; n=4; Burkh... 75 7e-12
UniRef50_Q238W6 Cluster: Adenylate and Guanylate cyclase catalyt... 74 2e-11
UniRef50_Q8F1T7 Cluster: Adenylate cyclase; n=2; Leptospira inte... 73 2e-11
UniRef50_UPI00015B5C60 Cluster: PREDICTED: similar to soluble gu... 72 5e-11
UniRef50_A0E8U0 Cluster: Cation-transporting ATPase; n=4; Parame... 72 5e-11
UniRef50_A0YSC8 Cluster: Extracellular ligand-binding receptor; ... 72 6e-11
UniRef50_Q10XK8 Cluster: Adenylate/guanylate cyclase precursor; ... 71 8e-11
UniRef50_A0CQM4 Cluster: Chromosome undetermined scaffold_24, wh... 71 8e-11
UniRef50_Q0LMK3 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 71 1e-10
UniRef50_Q22AU0 Cluster: Adenylate and Guanylate cyclase catalyt... 71 1e-10
UniRef50_A0DVQ1 Cluster: Chromosome undetermined scaffold_66, wh... 71 1e-10
UniRef50_Q8F778 Cluster: Adenylate cyclase; n=3; Leptospira inte... 71 1e-10
UniRef50_A7BXS6 Cluster: Adenylate/guanylate cyclase; n=1; Beggi... 71 1e-10
UniRef50_A0C7P7 Cluster: Chromosome undetermined scaffold_156, w... 71 1e-10
UniRef50_A0EHP6 Cluster: Cation-transporting ATPase; n=3; Parame... 70 2e-10
UniRef50_Q6BG52 Cluster: Guanylyl cyclase, putative; n=4; Parame... 70 2e-10
UniRef50_UPI00006CEB6E Cluster: Adenylate and Guanylate cyclase ... 69 4e-10
UniRef50_Q89SW2 Cluster: Two-component hybrid sensor and regulat... 69 4e-10
UniRef50_A0YPF4 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC... 69 4e-10
UniRef50_Q24GP9 Cluster: Adenylate and Guanylate cyclase catalyt... 69 4e-10
UniRef50_Q98GN7 Cluster: Cyclase; n=1; Mesorhizobium loti|Rep: C... 69 6e-10
UniRef50_Q9EXQ2 Cluster: Adenylate cyclase; n=3; Oscillatoriales... 69 6e-10
UniRef50_Q1H0Z8 Cluster: Adenylate/guanylate cyclase; n=1; Methy... 69 6e-10
UniRef50_Q231I7 Cluster: Adenylate and Guanylate cyclase catalyt... 69 6e-10
UniRef50_A0D3H6 Cluster: Chromosome undetermined scaffold_36, wh... 68 8e-10
UniRef50_A0CEN0 Cluster: Chromosome undetermined scaffold_172, w... 68 8e-10
UniRef50_Q9XTY1 Cluster: Guanylate cyclase; n=2; Caenorhabditis|... 68 1e-09
UniRef50_Q16JH8 Cluster: Soluble guanylate cyclase gcy; n=2; Cul... 68 1e-09
UniRef50_A7AX98 Cluster: Adenylate and guanylate cyclase catalyt... 68 1e-09
UniRef50_A0BPN4 Cluster: Chromosome undetermined scaffold_12, wh... 68 1e-09
UniRef50_Q8INF0 Cluster: Soluble guanylate cyclase 88E; n=12; Co... 68 1e-09
UniRef50_UPI00006CF863 Cluster: Adenylate and Guanylate cyclase ... 67 1e-09
UniRef50_UPI00006CB402 Cluster: Adenylate and Guanylate cyclase ... 67 1e-09
UniRef50_Q9U928 Cluster: Guanylyl cyclase; n=2; Tetrahymena pyri... 67 1e-09
UniRef50_UPI00006CFA91 Cluster: Adenylate and Guanylate cyclase ... 67 2e-09
UniRef50_Q5UFR4 Cluster: Cya1625; n=1; Mycobacterium smegmatis|R... 67 2e-09
UniRef50_Q1NSQ3 Cluster: Adenylate cyclase; n=1; delta proteobac... 67 2e-09
UniRef50_A0YN57 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC... 67 2e-09
UniRef50_Q9XZS0 Cluster: Guanylyl cyclase; n=4; cellular organis... 67 2e-09
UniRef50_UPI000038D385 Cluster: COG2114: Adenylate cyclase, fami... 66 2e-09
UniRef50_Q1NWK5 Cluster: Guanylate cyclase; n=2; delta proteobac... 66 2e-09
UniRef50_A7C2F8 Cluster: Rh-like protein/ammonium transporter; n... 66 3e-09
UniRef50_A5K544 Cluster: Adenylate and Guanylate cyclase catalyt... 66 3e-09
UniRef50_A0C5P9 Cluster: Chromosome undetermined scaffold_150, w... 66 3e-09
UniRef50_Q92WJ5 Cluster: Putative regulatory protein; n=2; Sinor... 66 4e-09
UniRef50_A1ZVN3 Cluster: Adenylate or guanylate cyclase; n=1; Mi... 66 4e-09
UniRef50_Q9N9H5 Cluster: Guanylyl cyclase; n=3; Plasmodium falci... 66 4e-09
UniRef50_P0A4Y1 Cluster: Adenylate cyclase; n=15; Mycobacterium|... 66 4e-09
UniRef50_Q7YXG1 Cluster: Soluble guanylyl cyclase 2 beta; n=1; L... 65 5e-09
UniRef50_Q16W55 Cluster: Adenylate cyclase; n=1; Aedes aegypti|R... 65 5e-09
UniRef50_Q4SU92 Cluster: Chromosome 3 SCAF13974, whole genome sh... 64 9e-09
UniRef50_Q23DS0 Cluster: Adenylate and Guanylate cyclase catalyt... 64 1e-08
UniRef50_A1ZFP4 Cluster: Two-component hybrid sensor and regulat... 64 2e-08
UniRef50_A0YS29 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC... 64 2e-08
UniRef50_P33402 Cluster: Guanylate cyclase soluble subunit alpha... 64 2e-08
UniRef50_A1ZQH6 Cluster: Heat-stable enterotoxin receptor; n=1; ... 63 2e-08
UniRef50_A0YQ82 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC... 63 2e-08
UniRef50_Q4UFI5 Cluster: Cation-transporting ATPase; n=1; Theile... 63 2e-08
UniRef50_Q4N3Z0 Cluster: Cation-transporting ATPase; n=1; Theile... 63 2e-08
UniRef50_O01779 Cluster: Guanylate cyclase; n=1; Caenorhabditis ... 63 2e-08
UniRef50_A0EAN1 Cluster: Chromosome undetermined scaffold_86, wh... 63 2e-08
UniRef50_UPI0000586706 Cluster: PREDICTED: similar to guanylate ... 62 4e-08
UniRef50_A7RZH8 Cluster: Predicted protein; n=1; Nematostella ve... 62 4e-08
UniRef50_UPI0000E49095 Cluster: PREDICTED: similar to guanylate ... 62 5e-08
UniRef50_Q28S34 Cluster: Adenylate/guanylate cyclase; n=1; Janna... 62 5e-08
UniRef50_A3WBP2 Cluster: Adenylate/guanylate cyclase; n=1; Eryth... 62 5e-08
UniRef50_Q5CUX5 Cluster: P-type ATpase fused to two adenyl cycla... 62 5e-08
UniRef50_Q23310 Cluster: Guanylate cyclase; n=1; Caenorhabditis ... 62 5e-08
UniRef50_O96993 Cluster: Guanylate cyclase; n=1; Heterodera glyc... 62 7e-08
UniRef50_A7RN72 Cluster: Predicted protein; n=1; Nematostella ve... 62 7e-08
UniRef50_Q07093 Cluster: Head-specific guanylate cyclase; n=8; E... 62 7e-08
UniRef50_A3I1K5 Cluster: Adenylate/guanylate cyclase; n=1; Algor... 61 9e-08
UniRef50_Q9GVB8 Cluster: Guanylyl cyclase enzyme; n=3; Plasmodiu... 61 9e-08
UniRef50_UPI00015B6146 Cluster: PREDICTED: similar to ENSANGP000... 61 1e-07
UniRef50_A2DDF2 Cluster: Adenylate and Guanylate cyclase catalyt... 61 1e-07
UniRef50_Q9ERL9 Cluster: Guanylate cyclase soluble subunit alpha... 61 1e-07
UniRef50_Q02108 Cluster: Guanylate cyclase soluble subunit alpha... 61 1e-07
UniRef50_A0LXB4 Cluster: Secreted protein containing adenylate/g... 60 2e-07
UniRef50_A2FPM7 Cluster: Adenylate and Guanylate cyclase catalyt... 60 2e-07
UniRef50_Q7ZSZ5 Cluster: Soluble guanylyl cyclase alpha2 subunit... 60 2e-07
UniRef50_A1ZW48 Cluster: Adenylate cyclase; n=1; Microscilla mar... 60 2e-07
UniRef50_Q7JP51 Cluster: Guanylate cyclase; n=6; Caenorhabditis|... 60 2e-07
UniRef50_A2E4D6 Cluster: Adenylate and Guanylate cyclase catalyt... 60 3e-07
UniRef50_Q03100 Cluster: Adenylate cyclase, aggregation specific... 60 3e-07
UniRef50_UPI00015B6145 Cluster: PREDICTED: similar to guanylate ... 59 3e-07
UniRef50_A1ZJP1 Cluster: Adenylate cyclase; n=1; Microscilla mar... 59 3e-07
UniRef50_Q4Z354 Cluster: Guanylyl cyclase, putative; n=8; Plasmo... 59 3e-07
UniRef50_A2FB45 Cluster: Adenylate and Guanylate cyclase catalyt... 59 3e-07
UniRef50_A2DKP6 Cluster: Adenylate and Guanylate cyclase catalyt... 59 3e-07
UniRef50_A0MJN0 Cluster: Guanylate cyclase beta; n=11; Plasmodiu... 59 3e-07
UniRef50_UPI0000DB755E Cluster: PREDICTED: similar to Adenylyl c... 59 5e-07
UniRef50_UPI0000ECB130 Cluster: Guanylate cyclase soluble subuni... 59 5e-07
UniRef50_A7BYP5 Cluster: Adenylate/guanylate cyclase; n=1; Beggi... 59 5e-07
UniRef50_Q18331 Cluster: Guanylyl cyclase protein 11; n=2; Caeno... 59 5e-07
UniRef50_O75343 Cluster: Guanylate cyclase soluble subunit beta-... 59 5e-07
UniRef50_A5P476 Cluster: Putative adenylate/guanylate cyclase; n... 58 6e-07
UniRef50_A3HVA1 Cluster: Adenylate/guanylate cyclase; n=1; Algor... 58 6e-07
UniRef50_A2G2M4 Cluster: Adenylate and Guanylate cyclase catalyt... 58 6e-07
UniRef50_Q96KY6 Cluster: ADCY4 protein; n=20; Euteleostomi|Rep: ... 58 6e-07
UniRef50_A1ZXW2 Cluster: Adenylate cyclase; n=1; Microscilla mar... 58 8e-07
UniRef50_A1ZSW4 Cluster: Atrial natriuretic peptide receptor A; ... 58 8e-07
UniRef50_Q47AI8 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 58 1e-06
UniRef50_A4AWH6 Cluster: Adenylate/guanylate cyclase; n=1; Flavo... 58 1e-06
UniRef50_Q8MLX0 Cluster: CG3216-PB, isoform B; n=7; Endopterygot... 58 1e-06
UniRef50_Q7YXG2 Cluster: Soluble guanylyl cyclase 1 beta; n=1; L... 58 1e-06
UniRef50_O97053 Cluster: Guanylate cyclase; n=1; Stichopus japon... 58 1e-06
UniRef50_A2FZG6 Cluster: Adenylate and Guanylate cyclase catalyt... 58 1e-06
UniRef50_UPI0000F2B0A8 Cluster: PREDICTED: similar to guanylyl c... 57 1e-06
UniRef50_UPI0000E47CE0 Cluster: PREDICTED: hypothetical protein;... 57 1e-06
UniRef50_UPI00005841ED Cluster: PREDICTED: similar to soluble gu... 57 1e-06
UniRef50_A2DC46 Cluster: Adenylate and Guanylate cyclase catalyt... 57 2e-06
UniRef50_A2DBX9 Cluster: Adenylate and Guanylate cyclase catalyt... 57 2e-06
UniRef50_Q07553 Cluster: Guanylate cyclase 32E precursor; n=3; D... 57 2e-06
UniRef50_UPI0000E4A009 Cluster: PREDICTED: similar to soluble gu... 56 2e-06
UniRef50_Q17BS6 Cluster: Guanylate cyclase; n=2; Culicidae|Rep: ... 56 2e-06
UniRef50_A2D8T2 Cluster: Adenylate and Guanylate cyclase catalyt... 56 2e-06
UniRef50_Q5YLC2 Cluster: Soluble guanylyl cyclase beta; n=1; Chl... 56 3e-06
UniRef50_Q03101 Cluster: Adenylate cyclase, germination specific... 56 3e-06
UniRef50_A1ZSW5 Cluster: Adenylate cyclase; n=1; Microscilla mar... 56 4e-06
UniRef50_Q9GT36 Cluster: Guanylate cyclase; n=1; Heterodera glyc... 56 4e-06
UniRef50_Q8TA72 Cluster: Guanylate cyclase; n=2; Eumetazoa|Rep: ... 56 4e-06
UniRef50_A2FSM3 Cluster: Adenylate and Guanylate cyclase catalyt... 56 4e-06
UniRef50_Q6TL19 Cluster: Guanylate cyclase 2G precursor; n=6; Mu... 56 4e-06
UniRef50_A3HV63 Cluster: Adenylate or guanylate cyclase; n=1; Al... 55 6e-06
UniRef50_Q6UCJ4 Cluster: Guanylate cyclase PcGC-M2 precursor; n=... 55 6e-06
UniRef50_UPI00015B48AF Cluster: PREDICTED: similar to ENSANGP000... 55 8e-06
UniRef50_Q73RD3 Cluster: Adenylate/guanylate cyclase catalytic d... 55 8e-06
UniRef50_Q15T90 Cluster: Adenylate/guanylate cyclase; n=1; Pseud... 55 8e-06
UniRef50_Q1EC29 Cluster: IP04501p; n=7; Endopterygota|Rep: IP045... 55 8e-06
UniRef50_A2DTD4 Cluster: Adenylate and Guanylate cyclase catalyt... 55 8e-06
UniRef50_Q5SR07 Cluster: Natriuretic peptide receptor A/guanylat... 55 8e-06
UniRef50_P16066 Cluster: Atrial natriuretic peptide receptor A p... 55 8e-06
UniRef50_Q02153 Cluster: Guanylate cyclase soluble subunit beta-... 54 1e-05
UniRef50_UPI0000E4745B Cluster: PREDICTED: similar to ENSANGP000... 54 2e-05
UniRef50_Q7UN49 Cluster: Adenylate cyclase 1; n=1; Pirellula sp.... 54 2e-05
UniRef50_Q9VF17 Cluster: Guanylate cyclase; n=7; Endopterygota|R... 54 2e-05
UniRef50_Q8T8L6 Cluster: Guanylate cyclase; n=5; Caenorhabditis|... 54 2e-05
UniRef50_Q8IQK2 Cluster: Guanylate cyclase; n=6; Diptera|Rep: Gu... 54 2e-05
UniRef50_A7SPS9 Cluster: Predicted protein; n=11; Eumetazoa|Rep:... 54 2e-05
UniRef50_Q9VA09 Cluster: CG1470-PA; n=6; Diptera|Rep: CG1470-PA ... 53 2e-05
UniRef50_Q9GT37 Cluster: Guanylate cyclase; n=2; Heterodera glyc... 53 2e-05
UniRef50_Q19768 Cluster: Guanylate cyclase; n=2; Caenorhabditis|... 53 2e-05
UniRef50_Q174S2 Cluster: Guanylate cyclase; n=7; Coelomata|Rep: ... 53 2e-05
UniRef50_A2EEV5 Cluster: Adenylate and Guanylate cyclase catalyt... 53 2e-05
UniRef50_Q4T0M0 Cluster: Guanylate cyclase; n=1; Tetraodon nigro... 53 3e-05
UniRef50_A2ES71 Cluster: Adenylate and Guanylate cyclase catalyt... 53 3e-05
UniRef50_UPI0000D5787E Cluster: PREDICTED: similar to CG9783-PA;... 52 4e-05
UniRef50_UPI000069F10A Cluster: Adenylate cyclase type 6 (EC 4.6... 52 4e-05
UniRef50_Q17AF9 Cluster: Guanylate cyclase; n=1; Aedes aegypti|R... 52 4e-05
UniRef50_A2DFE4 Cluster: Adenylate and Guanylate cyclase catalyt... 52 4e-05
UniRef50_Q4TAT8 Cluster: Guanylate cyclase; n=2; Tetraodontidae|... 52 5e-05
UniRef50_Q4SW10 Cluster: Guanylate cyclase; n=4; Tetraodontidae|... 52 5e-05
UniRef50_Q2L6K5 Cluster: Guanylate cyclase; n=3; Caenorhabditis|... 52 5e-05
UniRef50_A7RN69 Cluster: Predicted protein; n=2; Nematostella ve... 52 5e-05
UniRef50_Q9VN32 Cluster: Guanylate cyclase; n=5; Diptera|Rep: Gu... 52 7e-05
UniRef50_Q7YWK7 Cluster: Soluble guanylate cyclase subunit; n=1;... 52 7e-05
UniRef50_UPI0000E47581 Cluster: PREDICTED: similar to natriureti... 51 9e-05
UniRef50_A2BFQ0 Cluster: Guanylate cyclase; n=3; Danio rerio|Rep... 51 9e-05
UniRef50_Q5DTS7 Cluster: MKIAA4004 protein; n=2; Murinae|Rep: MK... 51 9e-05
UniRef50_A6PTF8 Cluster: Putative adenylate/guanylate cyclase; n... 51 9e-05
UniRef50_A6FX69 Cluster: Adenylate or guanylate cyclase; n=1; Pl... 51 9e-05
UniRef50_A2ECV6 Cluster: Adenylate and Guanylate cyclase catalyt... 51 9e-05
UniRef50_P51841 Cluster: Retinal guanylyl cyclase 2 precursor; n... 51 9e-05
UniRef50_UPI0000E46159 Cluster: PREDICTED: similar to natriureti... 51 1e-04
UniRef50_O77149 Cluster: NO-insensitive guanylyl cyclase; n=1; M... 51 1e-04
UniRef50_A7RUA8 Cluster: Predicted protein; n=1; Nematostella ve... 50 2e-04
UniRef50_A2DJ96 Cluster: Adenylate and Guanylate cyclase catalyt... 50 2e-04
UniRef50_UPI00015B5A8E Cluster: PREDICTED: similar to ENSANGP000... 50 2e-04
UniRef50_Q17010 Cluster: Soluble guanylate cyclase; n=14; Cellia... 50 2e-04
UniRef50_O02298 Cluster: Soluble guanylate cyclase gcy-35; n=2; ... 50 2e-04
UniRef50_UPI0000E45ED9 Cluster: PREDICTED: similar to ENSANGP000... 50 3e-04
UniRef50_Q19187 Cluster: Guanylate cyclase; n=3; Bilateria|Rep: ... 50 3e-04
UniRef50_A2GA06 Cluster: Adenylate and Guanylate cyclase catalyt... 50 3e-04
UniRef50_A2EQT4 Cluster: Adenylate and Guanylate cyclase catalyt... 50 3e-04
UniRef50_P92006 Cluster: Soluble guanylate cyclase gcy-34; n=7; ... 50 3e-04
UniRef50_UPI0000F1D453 Cluster: PREDICTED: similar to receptor t... 49 4e-04
UniRef50_A7RN70 Cluster: Predicted protein; n=1; Nematostella ve... 49 4e-04
UniRef50_Q09435 Cluster: Guanylate cyclase receptor-type gcy-1 p... 49 4e-04
UniRef50_Q8DGN6 Cluster: Adenylate cyclase; n=1; Synechococcus e... 49 5e-04
UniRef50_O16715 Cluster: Guanylate cyclase; n=3; Caenorhabditis|... 49 5e-04
UniRef50_P25092 Cluster: Heat-stable enterotoxin receptor precur... 49 5e-04
UniRef50_A7NLF3 Cluster: Adenylate/guanylate cyclase with GAF se... 48 7e-04
UniRef50_Q8MZE0 Cluster: AT09365p; n=1; Drosophila melanogaster|... 48 7e-04
UniRef50_A2FG49 Cluster: Adenylate and Guanylate cyclase catalyt... 48 7e-04
UniRef50_A5NV94 Cluster: Response regulator receiver protein; n=... 48 9e-04
UniRef50_A0QDI3 Cluster: Adenylate and Guanylate cyclase catalyt... 48 9e-04
UniRef50_A0LFQ5 Cluster: Adenylate/guanylate cyclase precursor; ... 48 9e-04
UniRef50_Q9NGZ8 Cluster: Guanylyl cyclase; n=4; Caenorhabditis|R... 48 9e-04
UniRef50_Q18628 Cluster: Putative uncharacterized protein acy-3;... 48 9e-04
UniRef50_P16065 Cluster: Speract receptor precursor; n=7; Euechi... 48 9e-04
UniRef50_Q86C56 Cluster: Soluble guanylate cyclase gcy-31; n=4; ... 48 9e-04
UniRef50_Q10029 Cluster: Guanylate cyclase; n=1; Caenorhabditis ... 48 0.001
UniRef50_A7S7B2 Cluster: Predicted protein; n=1; Nematostella ve... 48 0.001
UniRef50_A2FWD6 Cluster: Adenylate and Guanylate cyclase catalyt... 47 0.002
UniRef50_A2F3K7 Cluster: Adenylate and Guanylate cyclase catalyt... 47 0.002
UniRef50_A2DLQ6 Cluster: Adenylate and Guanylate cyclase catalyt... 47 0.002
UniRef50_Q75V80 Cluster: Guanylate cyclase; n=11; Euteleostomi|R... 47 0.002
UniRef50_Q9GYQ4 Cluster: Guanylyl cyclase protein 8; n=3; Caenor... 47 0.002
UniRef50_Q2L6K7 Cluster: Recepotor type guanyly cyclase; n=1; Ca... 47 0.002
UniRef50_A2EN44 Cluster: Adenylate and Guanylate cyclase catalyt... 47 0.002
UniRef50_A2E7P5 Cluster: Adenylate and Guanylate cyclase catalyt... 46 0.003
UniRef50_Q4RYJ0 Cluster: Guanylate cyclase; n=2; Tetraodontidae|... 46 0.005
UniRef50_Q3A5C7 Cluster: Predicted ATPase, putative adenylate/gu... 46 0.005
UniRef50_Q7Q9W6 Cluster: ENSANGP00000003998; n=1; Anopheles gamb... 46 0.005
UniRef50_Q2L6K6 Cluster: Guanylate cyclase; n=3; Caenorhabditis|... 46 0.005
UniRef50_A7S7B3 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.005
UniRef50_Q02846 Cluster: Retinal guanylyl cyclase 1 precursor; n... 46 0.005
UniRef50_A0LKW1 Cluster: Adenylate/guanylate cyclase; n=1; Syntr... 45 0.006
UniRef50_UPI0000F1EB17 Cluster: PREDICTED: similar to ENSANGP000... 45 0.008
UniRef50_UPI00006975C6 Cluster: Guanylyl CYclase family member (... 45 0.008
UniRef50_Q7R2Z8 Cluster: GLP_385_25897_32469; n=1; Giardia lambl... 45 0.008
UniRef50_A2FID0 Cluster: Adenylate and Guanylate cyclase catalyt... 45 0.008
UniRef50_A2FW09 Cluster: Adenylate and Guanylate cyclase catalyt... 44 0.011
UniRef50_A2EII6 Cluster: Adenylate and Guanylate cyclase catalyt... 44 0.011
UniRef50_Q9JK77 Cluster: Adenylyl cyclase 3; n=7; Euteleostomi|R... 44 0.014
UniRef50_Q2BGD8 Cluster: Adenylate cyclase; n=1; Neptuniibacter ... 44 0.014
UniRef50_Q113T7 Cluster: Adenylate/guanylate cyclase; n=1; Trich... 44 0.014
UniRef50_Q9U317 Cluster: Putative uncharacterized protein gcy-25... 44 0.014
UniRef50_UPI0000E4627A Cluster: PREDICTED: similar to membrane g... 44 0.019
UniRef50_A7SJA1 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 44 0.019
UniRef50_A2GB93 Cluster: Adenylate and Guanylate cyclase catalyt... 44 0.019
UniRef50_Q9VEU5 Cluster: Soluble guanylate cyclase 89Db; n=6; Di... 44 0.019
UniRef50_Q4T7S3 Cluster: Guanylate cyclase; n=1; Tetraodon nigro... 43 0.025
UniRef50_Q92YL0 Cluster: Putative adenylate cyclase; n=1; Sinorh... 43 0.032
UniRef50_Q0VR65 Cluster: Adenylate cyclase; n=1; Alcanivorax bor... 43 0.032
UniRef50_Q0LGQ8 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 43 0.032
UniRef50_A2EN10 Cluster: Adenylate and Guanylate cyclase catalyt... 43 0.032
UniRef50_A2EII5 Cluster: Adenylate and Guanylate cyclase catalyt... 43 0.032
UniRef50_A1T6C4 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 42 0.043
UniRef50_Q8IT60 Cluster: Guanylate cyclase; n=3; Coelomata|Rep: ... 42 0.043
UniRef50_A2FAE9 Cluster: Adenylate and Guanylate cyclase catalyt... 42 0.043
UniRef50_Q0EZ20 Cluster: Adenylate/Guanylate Cyclase; n=1; Marip... 42 0.057
UniRef50_Q95NK5 Cluster: Soluble guanylyl cyclase beta1; n=2; St... 42 0.057
UniRef50_Q8I4N4 Cluster: Putative uncharacterized protein daf-11... 42 0.075
UniRef50_A2G2Z5 Cluster: Adenylate and Guanylate cyclase catalyt... 42 0.075
UniRef50_Q2K6R9 Cluster: Adenylate cyclase protein; n=4; Rhizobi... 41 0.099
UniRef50_Q0LCB6 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 41 0.099
UniRef50_Q6E6T5 Cluster: L3i88 isoform b; n=5; Dictyocaulus vivi... 41 0.099
UniRef50_Q23496 Cluster: Guanylate cyclase; n=2; Caenorhabditis|... 41 0.099
UniRef50_A2DVH2 Cluster: Adenylate and Guanylate cyclase catalyt... 41 0.099
UniRef50_Q6DNF3 Cluster: Soluble guanylate cyclase gcy-37; n=2; ... 41 0.099
UniRef50_A4Z0R3 Cluster: Putative Adenylate cyclase; n=1; Bradyr... 41 0.13
UniRef50_Q9XVV4 Cluster: Guanylate cyclase; n=2; Caenorhabditis|... 41 0.13
UniRef50_A2DWV8 Cluster: Adenylate and Guanylate cyclase catalyt... 41 0.13
UniRef50_UPI0000586B0F Cluster: PREDICTED: similar to receptor t... 40 0.17
UniRef50_UPI000038C573 Cluster: COG2114: Adenylate cyclase, fami... 40 0.17
UniRef50_UPI000065CD57 Cluster: Heat-stable enterotoxin receptor... 40 0.17
UniRef50_Q3DYQ5 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 40 0.17
UniRef50_Q10Z12 Cluster: Adenylate/guanylate cyclase; n=1; Trich... 40 0.17
UniRef50_O62026 Cluster: Putative uncharacterized protein gcy-29... 40 0.17
UniRef50_Q4BYX5 Cluster: Guanylate cyclase:Histidine kinase, HAM... 40 0.23
UniRef50_Q164Z4 Cluster: Conserved domain protein; n=1; Roseobac... 40 0.23
UniRef50_A7HW36 Cluster: Putative Chase2 sensor protein precurso... 40 0.23
UniRef50_Q10W13 Cluster: Adenylate/guanylate cyclase; n=2; Oscil... 40 0.30
UniRef50_A3PVY7 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 40 0.30
UniRef50_A2DY07 Cluster: Adenylate and Guanylate cyclase catalyt... 40 0.30
UniRef50_Q08U17 Cluster: Putative uncharacterized protein; n=1; ... 39 0.40
UniRef50_A0LQP8 Cluster: Adenylate/guanylate cyclase; n=1; Syntr... 39 0.40
UniRef50_A2G3F5 Cluster: Adenylate and Guanylate cyclase catalyt... 39 0.40
UniRef50_A2FLP2 Cluster: Adenylate and Guanylate cyclase catalyt... 39 0.40
UniRef50_Q21LJ4 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 39 0.53
UniRef50_Q1VN94 Cluster: Two-component hybrid sensor and regulat... 39 0.53
UniRef50_A6GG85 Cluster: Putative adenylate cyclase; n=1; Plesio... 39 0.53
UniRef50_A0YII8 Cluster: Adenylate cyclase; n=2; Bacteria|Rep: A... 39 0.53
UniRef50_Q8YMH0 Cluster: Adenylate cyclase carring two-component... 38 0.70
UniRef50_Q89SR2 Cluster: Bll2338 protein; n=4; Bradyrhizobiaceae... 38 0.70
UniRef50_Q3DXI8 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 38 0.70
UniRef50_Q20XY3 Cluster: Adenylate/guanylate cyclase; n=1; Rhodo... 38 0.70
UniRef50_Q08MU2 Cluster: Putative uncharacterized protein; n=2; ... 38 0.70
UniRef50_A2C6I2 Cluster: Putative uncharacterized protein; n=1; ... 38 0.70
UniRef50_A0PTR6 Cluster: Adenylylate/guanylate cyclase; n=1; Myc... 38 0.70
UniRef50_O16544 Cluster: Guanylate cyclase; n=3; Caenorhabditis|... 38 0.70
UniRef50_A7S909 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.70
UniRef50_P90895 Cluster: Soluble guanylate cyclase gcy-33; n=2; ... 38 0.70
UniRef50_P40137 Cluster: Adenylate cyclase 1; n=2; Stigmatella a... 38 0.70
UniRef50_Q8F2W9 Cluster: Adenylate cyclase; n=4; Leptospira|Rep:... 38 0.92
UniRef50_Q2K476 Cluster: Adenylate cyclase protein; n=4; Rhizobi... 38 0.92
UniRef50_A0H4A6 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 38 0.92
UniRef50_Q2LQ30 Cluster: HD domain protein; n=1; Syntrophus acid... 38 1.2
UniRef50_Q1QA64 Cluster: Adenylate/guanylate cyclase; n=1; Psych... 38 1.2
UniRef50_A1G651 Cluster: Adenylate/guanylate cyclase; n=2; Salin... 38 1.2
UniRef50_A2FKW6 Cluster: Adenylate and Guanylate cyclase catalyt... 38 1.2
UniRef50_A2FB36 Cluster: Adenylate and Guanylate cyclase catalyt... 38 1.2
UniRef50_A0NC46 Cluster: ENSANGP00000018386; n=1; Anopheles gamb... 38 1.2
UniRef50_Q4SY29 Cluster: Guanylate cyclase; n=2; Tetraodontidae|... 37 1.6
UniRef50_Q4RZ92 Cluster: Chromosome 1 SCAF14944, whole genome sh... 37 1.6
UniRef50_Q89II7 Cluster: Bll5647 protein; n=5; Bradyrhizobiaceae... 37 1.6
UniRef50_A0Y8Z4 Cluster: Adenylate cyclase; n=1; marine gamma pr... 37 1.6
UniRef50_Q90WX1 Cluster: Guanylyl cyclase 2; n=7; Eumetazoa|Rep:... 37 2.1
UniRef50_Q4T7P7 Cluster: Chromosome undetermined SCAF8055, whole... 37 2.1
UniRef50_A7BVW4 Cluster: Adenylate/guanylate cyclase; n=1; Beggi... 37 2.1
UniRef50_A6LRL1 Cluster: Sensor protein; n=1; Clostridium beijer... 37 2.1
UniRef50_A5Z769 Cluster: Putative uncharacterized protein; n=1; ... 37 2.1
UniRef50_A0P034 Cluster: Adenylate cyclase; n=1; Stappia aggrega... 37 2.1
UniRef50_Q23BX5 Cluster: Putative uncharacterized protein; n=1; ... 37 2.1
UniRef50_A2DJR4 Cluster: Adenylate and Guanylate cyclase catalyt... 37 2.1
UniRef50_A6QRP6 Cluster: Predicted protein; n=1; Ajellomyces cap... 37 2.1
UniRef50_O14338 Cluster: Uncharacterized serine-rich protein C2F... 37 2.1
UniRef50_Q8F2D7 Cluster: Adenylate cyclase; n=2; Leptospira inte... 36 2.8
UniRef50_Q7A2G7 Cluster: Adenylate cyclase; n=4; Nostocaceae|Rep... 36 2.8
UniRef50_A6PCE2 Cluster: Putative adenylate/guanylate cyclase pr... 36 2.8
UniRef50_UPI0000383FA3 Cluster: COG4252: Predicted transmembrane... 36 3.7
UniRef50_Q98EW6 Cluster: Adenylate cyclase; Cya3; n=1; Mesorhizo... 36 3.7
UniRef50_Q6N2P9 Cluster: Adenylate/Guanylate cyclase; n=1; Rhodo... 36 3.7
UniRef50_Q07M97 Cluster: Adenylate/guanylate cyclase; n=7; Brady... 36 3.7
UniRef50_A2F7J9 Cluster: Adenylate and Guanylate cyclase catalyt... 36 3.7
UniRef50_P44443 Cluster: Ribonuclease E; n=97; Gammaproteobacter... 36 3.7
UniRef50_UPI00006CAA28 Cluster: hypothetical protein TTHERM_0032... 36 4.9
UniRef50_Q111B1 Cluster: Adenylate/guanylate cyclase; n=2; Bacte... 36 4.9
UniRef50_A4XM29 Cluster: Putative adenylate/guanylate cyclase; n... 36 4.9
UniRef50_A3Z3F8 Cluster: Adenylate cyclase; n=2; Synechococcus|R... 36 4.9
UniRef50_A3J080 Cluster: Putative uncharacterized protein; n=1; ... 36 4.9
UniRef50_Q4Y308 Cluster: Putative uncharacterized protein; n=1; ... 36 4.9
UniRef50_A0CYW4 Cluster: Chromosome undetermined scaffold_31, wh... 36 4.9
UniRef50_A2QII5 Cluster: Similarity: the ORF shows weak; n=17; E... 36 4.9
UniRef50_Q8EKX5 Cluster: Putative uncharacterized protein OB3457... 35 6.5
UniRef50_Q3DXV1 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 35 6.5
UniRef50_Q0LIY8 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 35 6.5
UniRef50_Q092U5 Cluster: Serine/threonine protein kinase; n=1; S... 35 6.5
UniRef50_A0P2D1 Cluster: Adenylate cyclase 1 protein; n=2; Stapp... 35 6.5
UniRef50_Q5CRV8 Cluster: Membrane associated adenyl cyclase with... 35 6.5
UniRef50_A2FHB2 Cluster: Putative uncharacterized protein; n=1; ... 35 6.5
UniRef50_UPI000065F95C Cluster: Homolog of Oryzias latipes "Solu... 35 8.6
UniRef50_Q2LS04 Cluster: Adenylate cyclase; n=1; Syntrophus acid... 35 8.6
UniRef50_P72951 Cluster: Adenylate cyclase; n=2; Chroococcales|R... 35 8.6
UniRef50_Q0VSG5 Cluster: Adenylate cyclase family proteine ident... 35 8.6
UniRef50_A5P1B9 Cluster: CHASE3 domain protein precursor; n=1; M... 35 8.6
UniRef50_A4B6Y6 Cluster: Adenylate/guanylate cyclase; n=1; Alter... 35 8.6
UniRef50_A0LB38 Cluster: Adenylate/guanylate cyclase; n=1; Magne... 35 8.6
UniRef50_Q4N058 Cluster: Putative uncharacterized protein; n=1; ... 35 8.6
UniRef50_A2DXL5 Cluster: Putative uncharacterized protein; n=1; ... 35 8.6
UniRef50_A0BG78 Cluster: Chromosome undetermined scaffold_105, w... 35 8.6
UniRef50_Q6CIU1 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 35 8.6
UniRef50_A4UBV9 Cluster: Cation-transporting ATPase; n=1; Magnap... 35 8.6
>UniRef50_UPI00015B5E7D Cluster: PREDICTED: similar to adenylate
cyclase type ix; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to adenylate cyclase type ix -
Nasonia vitripennis
Length = 1314
Score = 314 bits (771), Expect = 5e-84
Identities = 166/373 (44%), Positives = 222/373 (59%), Gaps = 27/373 (7%)
Query: 17 FESKHDPECSEGEDAQIRMAPHVQAYLARNNSTTNCCGLTIPIAFERAAPGTWWNPRFDS 76
F D ++ I +AP++Q YLA + CCG+ +P+ FERAAP +WWNP+FDS
Sbjct: 15 FTHAKDENNDASDEIHISLAPYIQTYLAHSGQGLGCCGVGLPVPFERAAPRSWWNPKFDS 74
Query: 77 EILEGQYRSSSFRQIRLRFRFALLYILIFSISWFVYFVVLGLNDVTVKWPFLCSLFAGVL 136
EILEGQY+ S+F QIRLRFR+AL YIL+ S+SW YFV+LG+ + ++ WP++ +F V
Sbjct: 75 EILEGQYKCSAFPQIRLRFRYALTYILLISVSWLAYFVILGIENNSIFWPYIAVMFTAVG 134
Query: 137 LITCIMLLVTFTNFYKVYTFKLSLVMAXXXXXXXXXXXXXXXXXXXXFYQAADISQSGHF 196
+ +L +T T+ Y+ +S+ +A ++ GHF
Sbjct: 135 AMVSAILYLTHTDHYRSIVLPISVGVALMLCCLSIVFLVYVPPDTDG------LTLVGHF 188
Query: 197 TMCIEXXXXXXXXXXXXXXACVILGIIYSIVFEVLNIVLHLSEQEWQ------------- 243
+C E AC ++ +YS +FE L + SE Q
Sbjct: 189 ALCSEILLLIYTVLPMPLYACTLICTLYSFLFEFLTAYYYGSESTKQDVHSVDITLTPHE 248
Query: 244 ----ASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKM 299
A+ + +RIL+Q+C+H+IGVHI +MTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKM
Sbjct: 249 DINFATTLAIRILMQICIHLIGVHILIMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKM 308
Query: 300 IHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSI 359
IHSVMPPK+A LM E E + + I + +DI+SLFRPFNM MD+VSI
Sbjct: 309 IHSVMPPKVADWLMEESERERERE----DSLKKGSIPSNNTDIRSLFRPFNMHSMDDVSI 364
Query: 360 LFADIVGFTRMSS 372
LFADIVGFT+MSS
Sbjct: 365 LFADIVGFTKMSS 377
Score = 172 bits (418), Expect = 3e-41
Identities = 113/289 (39%), Positives = 165/289 (57%), Gaps = 33/289 (11%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+MIEAI++FD ER EG+NMRVGVHTGTVLCGIVGT+RFKFDVWSNDVT ANK+ES+GKPG
Sbjct: 437 AMIEAIKQFDIERREGVNMRVGVHTGTVLCGIVGTKRFKFDVWSNDVTLANKLESTGKPG 496
Query: 432 RVHISEETSQFLGGSYILEEGEEVFGHKTYFIEGRQVFCPYDREQCLTPSNPVNLRXXXX 491
RVH+SE+T FL Y+ E+GE V G KTYFI+ R+ + + ++P ++
Sbjct: 497 RVHLSEKTLSFLEEQYLTEDGEPVNGIKTYFIKTRK--ADFMSQFINNVNSPTSI----- 549
Query: 492 XXXXXXXXXXXNYFTAPLTPKTEDKLNLRKPNSNNFLSPTPFNFRAKASSLPSILDSDTE 551
+ A + +T+ + + +N+ + + +A +SLPSILDSD +
Sbjct: 550 -----SPVLHARHRLASCSNQTKPRPHYLHMVTNS----SSYRMKA--NSLPSILDSDND 598
Query: 552 LDDNRDKGLTERTDSSSKSPTSVGSYG-KYTNKLKNWKVPRFLRKHSDT-PLHGIKKEDA 609
D DK + ++KSPTS SYG K + + K W R+L++ T + + +ED
Sbjct: 599 ADQGDDK------EGTNKSPTSTASYGKKKSGRSKAW---RYLQRQRTTEEMTPLDREDR 649
Query: 610 SDKTIHLLERGDVSVCVQS----SNGYQQVPIVIESQDNKRPLQSSSKL 654
+ +G ++ S SNG Q+ + + + P+ SS L
Sbjct: 650 RGVIVAEANQGLMAASATSASLESNGLQKATVSNGVEMDPNPMPSSPLL 698
Score = 49.2 bits (112), Expect = 4e-04
Identities = 22/86 (25%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
Query: 372 SMIEAIQEFDRER-GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
+M + I +F+++ G + +RVG + G V G++G+ + +D+W + V A++M+S+G
Sbjct: 1212 AMHKVIYDFNQDLLGFKLILRVGFNFGDVTAGVIGSSKLYYDIWGDAVNIASRMDSTGVA 1271
Query: 431 GRVHISEETSQFLGGSYILEEGEEVF 456
G + + + Y E +V+
Sbjct: 1272 GEIQFASNCLDVIAERYNYEPRGQVY 1297
>UniRef50_UPI0000D55CA0 Cluster: PREDICTED: similar to CG9210-PA,
isoform A; n=2; Endopterygota|Rep: PREDICTED: similar to
CG9210-PA, isoform A - Tribolium castaneum
Length = 1370
Score = 291 bits (713), Expect = 6e-77
Identities = 158/350 (45%), Positives = 210/350 (60%), Gaps = 14/350 (4%)
Query: 26 SEGEDAQIRMAPHVQAYLARNNSTTNCCGLTIPIAFERAAPGTWWNPRFDSEILEGQYRS 85
S+ E+AQ+ + P Q YLA + C G PI FERAA +WW+P FDSEILE QYR
Sbjct: 17 SDDENAQLSLDPQTQLYLAHLSQQNGCWGRFFPIPFERAAQKSWWDPTFDSEILEEQYRR 76
Query: 86 SSFRQIRLRFRFALLYILIFSISWFVYFVVLGLNDVTVKWPFLCSLFAGVLLITCIMLLV 145
SS R +FR+AL Y+L+ S SW VYF+V GL T WP LC++ ++L +L +
Sbjct: 77 SSNPHSRFKFRYALWYMLLISSSWLVYFLVTGLVSETHHWPMLCTVLGTLILSVTTVLFL 136
Query: 146 TFTNFYKVYTFKLSLVMAXX--XXXXXXXXXXXXXXXXXXFYQAADISQSGHFTMCIEXX 203
T+T+ Y + +SL++A F +DIS GHF++CIE
Sbjct: 137 TYTDIYNNHMLLMSLIVAFVLCVISLSFVVLVPMKTDPLSFPITSDISPVGHFSICIEIL 196
Query: 204 XXXXXXXXXXXXACVILGIIYSIVFEVLNIVLHLSEQEWQASGMFVRILLQLCVHIIGVH 263
+ +G +YS FE L I L Q +AS + VR+L C+H+IG+H
Sbjct: 197 MLIYTLIPLKLYMSITIGFLYSAAFETLTI--SLQNQSLEASTITVRLLSHFCIHVIGLH 254
Query: 264 IYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTN 323
I +MT VRMR TFMKVGQSLLVRRQLE EK+LKE MIHS+MP +A L++E+ T +
Sbjct: 255 ILIMTNVRMRNTFMKVGQSLLVRRQLESEKKLKENMIHSLMPSSVAEWLLSEEETFTRS- 313
Query: 324 VKTYHNPLNSRISNP-GSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSS 372
+ R S+P +DI+SLFRPFNM+ M+NVSILFADIVGFT+M+S
Sbjct: 314 --------DQRNSDPETNDIRSLFRPFNMNRMENVSILFADIVGFTKMAS 355
Score = 230 bits (563), Expect = 8e-59
Identities = 144/330 (43%), Positives = 196/330 (59%), Gaps = 40/330 (12%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SMI+AI++FD+E+ EG+NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVT AN+MES+GKPG
Sbjct: 415 SMIQAIKQFDQEKNEGVNMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTLANRMESTGKPG 474
Query: 432 RVHISEETSQFLGGSYILEEGEEVFGHKTYFIEGRQVFCPYDREQCLTPSNPVNLRXXXX 491
VH+SE+T +FL Y+LEEGE V G KTYFI GR D+ TPS + R
Sbjct: 475 MVHVSEKTCEFLQDMYLLEEGEPVLGMKTYFILGR----TGDK----TPSYSGSFRAEGR 526
Query: 492 XXXXXXXXXXXNYFTA--PLTPKTE------DKLNLRKPNSNNFLSPTPFNFRAKASSLP 543
+ T+ ++P++ D +++ ++ N LSP + KASSLP
Sbjct: 527 QKYTNSLQLFVSPPTSSPSMSPQSRPRVLSCDTTHIKATHNPNMLSPDV--CKIKASSLP 584
Query: 544 SILDSDTELDDNRDKGLTERTDSSSKSPTSVGSYGKYTNKLKNWKVPRFLRKHSDTPLHG 603
SILDS+ E D T D + K+PTS S GKY+ KLKNWK+P+FLRK+ P
Sbjct: 585 SILDSENEQDGGDICKETSDCD-NIKTPTSTASSGKYSVKLKNWKMPKFLRKNDGKPELD 643
Query: 604 IKKEDASDKTIHLLERGDVSVCVQSSNGYQQVPIVIESQDNKRPLQSSSKLNIPQI---N 660
I+ S+ I S GYQQVP +IE+ + + S +++ + N
Sbjct: 644 IEVPANSEDRI--------------SGGYQQVPTIIETSNVSNGKKKDSFISVTDVDDDN 689
Query: 661 ETSSF----DREIIDIRSYLSQSRSNMSPF 686
+ SS ++ ID++SY+SQSRS++ +
Sbjct: 690 KRSSIFLDDPKDTIDVKSYISQSRSDIGQY 719
Score = 50.4 bits (115), Expect = 2e-04
Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 373 MIEAIQEFDRERGE-GINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
M I +F+R+ E + +R+G + G V ++G + +D+W + V A++M+S+G G
Sbjct: 1263 MQNVITDFNRDLLEFNLILRIGYNFGEVTAAVIGNTKLYYDIWGDAVNIASRMDSTGVNG 1322
Query: 432 RVHISEETSQFLGGSYILEEGEEVF 456
+ I E Q L Y+ V+
Sbjct: 1323 CIQIGENCLQVLETRYVFRPRGSVY 1347
>UniRef50_Q7QEP6 Cluster: ENSANGP00000019838; n=3; Bilateria|Rep:
ENSANGP00000019838 - Anopheles gambiae str. PEST
Length = 1536
Score = 271 bits (664), Expect = 5e-71
Identities = 163/375 (43%), Positives = 217/375 (57%), Gaps = 40/375 (10%)
Query: 29 EDAQIRMAPHVQAYLARNNSTTNCCGLTIPIAFERAAPGTWWNPRFDSEILEGQYRSSSF 88
ED QI +AP++Q+YL++ +CC + +P+AFERAAP +W +PRFDS +LEGQY++S F
Sbjct: 14 EDIQISLAPYIQSYLSQTGRRHSCCSVMLPVAFERAAPRSWCDPRFDSPVLEGQYQASVF 73
Query: 89 RQIRLRFRFALLYILIFSISWFVYFVVLGLNDVTVKWPFLCSLFAGVLLITCIMLLVTFT 148
Q+RL+FRFAL YIL+ S+ W +YF+ G + L + L L VT T
Sbjct: 74 PQLRLKFRFALFYILLCSLVWLLYFLFDG---GPTSFTLLTVSIGLIFLFALAGLWVTRT 130
Query: 149 NFYKVYTFKLSLVMAXXXXXXXXXXXXXXXXXXXXFYQAADISQSGHFTMCIEXXXXXXX 208
+ Y+ +T LS A +S GHF++CIE
Sbjct: 131 DLYRAHTHLLSSCCAVLLCLFSLCLLLLTREA---------LSPLGHFSICIEIVMLIYT 181
Query: 209 XXXXXXXACVILGIIYSIVFEVLNIVLHLSEQEWQ------------ASGM--------- 247
C + + YS+ FEVL+ LH + ++ A+G+
Sbjct: 182 IIPLPLWLCCTITMAYSVCFEVLSF-LHQTHYDYNSRPGGQPTVSPLAAGITTAARLLAE 240
Query: 248 ---FVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVM 304
+R+L+QLCVH+IG+ I +MT VRMRGTFMKVGQ+LLVRRQLEMEKQLKEKMIHS+M
Sbjct: 241 EIVLIRVLIQLCVHLIGIQILIMTVVRMRGTFMKVGQNLLVRRQLEMEKQLKEKMIHSMM 300
Query: 305 PPKLASNLMNEQ-VTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFAD 363
PPK+A L+ E T+ Y P R + P SD+KSLFRPF+M+ M+NVSILFAD
Sbjct: 301 PPKVADLLLKESGSVPKGTSFDQYPAP-GGRRTTP-SDLKSLFRPFHMNRMENVSILFAD 358
Query: 364 IVGFTRMSSMIEAIQ 378
IVGFTRMSS A Q
Sbjct: 359 IVGFTRMSSTKTAEQ 373
Score = 159 bits (386), Expect = 2e-37
Identities = 71/96 (73%), Positives = 84/96 (87%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MIE+I+ FD +R EGI MRVGVHTGTVLCGIVGT+R KFDVWSNDVT AN+MESSGKP +
Sbjct: 428 MIESIRVFDAQRNEGIKMRVGVHTGTVLCGIVGTKRVKFDVWSNDVTLANRMESSGKPDQ 487
Query: 433 VHISEETSQFLGGSYILEEGEEVFGHKTYFIEGRQV 468
VH+SEET FLG SYI+EEGEEV GH+TYF+ G+++
Sbjct: 488 VHVSEETCGFLGDSYIIEEGEEVDGHRTYFVLGKRL 523
Score = 60.1 bits (139), Expect = 2e-07
Identities = 28/86 (32%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Query: 372 SMIEAIQEFDRERGE-GINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
+M + ++ F+R+ E + MRVG + G V G++GT + +D+W + V A++M+S+G
Sbjct: 1421 AMQQVVESFNRDLLEFNLIMRVGYNFGDVTAGVIGTSKLYYDIWGDAVNVASRMDSTGVA 1480
Query: 431 GRVHISEETSQFLGGSYILEEGEEVF 456
GRV + + LG Y E +V+
Sbjct: 1481 GRVQVGADCIPVLGERYDFEPRGKVY 1506
Score = 42.3 bits (95), Expect = 0.043
Identities = 20/31 (64%), Positives = 26/31 (83%), Gaps = 1/31 (3%)
Query: 657 PQINETSSFDREIIDIRSYLSQSRSNMSPFA 687
P ++ S FD EIID+RSY+SQSRS++SPFA
Sbjct: 800 PHASQGSVFD-EIIDVRSYISQSRSDISPFA 829
>UniRef50_O16039 Cluster: Adenylyl cyclase isoform DAC9; n=4;
Sophophora|Rep: Adenylyl cyclase isoform DAC9 -
Drosophila melanogaster (Fruit fly)
Length = 1708
Score = 255 bits (625), Expect = 3e-66
Identities = 155/382 (40%), Positives = 213/382 (55%), Gaps = 38/382 (9%)
Query: 21 HDPECSEGEDAQIRMAPHVQAYLARNNSTTNCCGLTIPIAFERAAPGTWWNPRFDSEILE 80
+D + +D QI +APH+Q YL++ +CC + +P+AFERAA +W +P+FDS +LE
Sbjct: 8 NDSRANSTDDIQIALAPHIQTYLSQTGRRHSCCSVMLPVAFERAAAKSWLDPKFDSPVLE 67
Query: 81 GQYRSSSFRQIRLRFRFALLYILIFSISWFVYFVVLGLNDVTVKWPFLCSLFAGVLLITC 140
QY++S F +R+R+RF L YIL+ S+ W +YFVV G ++ W + S F+ + L+T
Sbjct: 68 EQYQASVFPHVRMRYRFTLSYILLCSLMWCLYFVVDGGSEDF--WRPISSSFSMLSLVTI 125
Query: 141 IMLLVTFTNFYKVYTFKLSLVMAXXXXXXXXXXXXXXXXXXXXFYQAADISQSGHFTMCI 200
+ L T + Y+ + S V A Y S GHF +C+
Sbjct: 126 MALCFTHWDLYREHRTVTSAVTALLLCGASLAFLT---------YTGRAFSPLGHFAICL 176
Query: 201 EXXXXXXXXXXXXXXACVILGIIYSIVFEVLN-IVLHLSE---------------QEWQA 244
E I YSI FE+++ +V+ S +A
Sbjct: 177 EIVLLIYTALPMPLWLGASTAISYSIAFEMVSHMVIGCSAIHGGPMHGGGGAAGGSGMEA 236
Query: 245 SG------MFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEK 298
+G + +RI+ L VH++GVH+ +M VRMRGTFMKVGQ+LLVRRQLEMEKQLKEK
Sbjct: 237 NGDPSNRILILRIMAHLSVHLVGVHVLIMNLVRMRGTFMKVGQNLLVRRQLEMEKQLKEK 296
Query: 299 MIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISNP--GSDIKSLFRPFNMSCMDN 356
MIHSVMPPK+A L+NE + + P S P +D+KSLFRPF+M M+N
Sbjct: 297 MIHSVMPPKVADMLLNE---GGPSGLDAGGLPPESHYMRPRASNDVKSLFRPFHMHSMEN 353
Query: 357 VSILFADIVGFTRMSSMIEAIQ 378
VSILFADIVGFTRMSS A Q
Sbjct: 354 VSILFADIVGFTRMSSTKTAEQ 375
Score = 167 bits (405), Expect = 1e-39
Identities = 78/113 (69%), Positives = 92/113 (81%), Gaps = 2/113 (1%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+A++ FD +R EG+ MRVGVHTGTVLCGIVGTRR KFDVWSNDV+ ANKMESSGKP +
Sbjct: 430 MIDAMRCFDAQRHEGVKMRVGVHTGTVLCGIVGTRRVKFDVWSNDVSLANKMESSGKPEQ 489
Query: 433 VHISEETSQFLGGSYILEEGEEVFGHKTYFIEGRQVFCPYDREQCLTPSNPVN 485
VHIS+ETS FLG +Y LEEGEEVFGH+TYF+ GR+ + R L+PS P N
Sbjct: 490 VHISQETSSFLGDAYYLEEGEEVFGHRTYFVVGRR--RDFTRTNSLSPSMPAN 540
Score = 59.7 bits (138), Expect = 3e-07
Identities = 25/86 (29%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Query: 372 SMIEAIQEFDRERGE-GINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
+M E + F+++ E + +R+G++ G V G++GT + +D+W + V A++M+S+G P
Sbjct: 1466 AMQEVVDAFNKDLLEFNLILRIGMNIGDVTAGVIGTSKLYYDIWGDAVNVASRMDSTGLP 1525
Query: 431 GRVHISEETSQFLGGSYILEEGEEVF 456
R+ + ++ FL Y E V+
Sbjct: 1526 NRIQVGKDCLPFLTNRYEFEPRGSVY 1551
Score = 35.9 bits (79), Expect = 3.7
Identities = 16/24 (66%), Positives = 22/24 (91%), Gaps = 1/24 (4%)
Query: 663 SSFDREIIDIRSYLSQSRSNMSPF 686
S +D +IID+RSY+SQSRS++SPF
Sbjct: 808 SMYD-DIIDVRSYISQSRSDISPF 830
>UniRef50_O60503 Cluster: Adenylate cyclase type 9; n=29;
Euteleostomi|Rep: Adenylate cyclase type 9 - Homo
sapiens (Human)
Length = 1353
Score = 170 bits (414), Expect = 1e-40
Identities = 115/332 (34%), Positives = 164/332 (49%), Gaps = 18/332 (5%)
Query: 57 IPIAFERAAPGTWWNPRFDSEILEGQYRSSSFRQIRLRFRFALLYILIFSISWFVYFVV- 115
+P FERA+ WW+P+FDS LE F Q + RFR+AL YI + W +YF V
Sbjct: 79 LPQLFERAS-SRWWDPKFDSVNLEEACLERCFPQTQRRFRYALFYIGFACLLWSIYFAVH 137
Query: 116 LGLNDVTVKWPFLCSLFA--GVLLITCIMLLV---TFTNF-YKVYTFKLSLVMAXXXXXX 169
+ + + P LC L G L T L +T+ + F L+L
Sbjct: 138 MRSRLIVMVAPALCFLLVCVGFFLFTFTKLYARHYAWTSLALTLLVFALTLAAQFQVLTP 197
Query: 170 XXXXXXXXXXXXXXFYQAADISQSGHFTMCIEXXXXXXXXXXXXXXACVILGIIYSIVFE 229
+SQ G F+MCIE + LG+ YS++FE
Sbjct: 198 VSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYTVMHLPLYLSLCLGVAYSVLFE 257
Query: 230 VLNIVLHLSEQEWQASG-------MFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQS 282
E + + G + R LL C+H IGVH+++M+ VR R TF+KVGQS
Sbjct: 258 TFGYHFR-DEACFPSPGAGALHWELLSRGLLHGCIHAIGVHLFVMSQVRSRSTFLKVGQS 316
Query: 283 LLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTY--HNPLNSRISNPGS 340
++ + LE+EK LKE+MIHSVMP +A +LM + E++ +VK + +P N + +
Sbjct: 317 IMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQ 376
Query: 341 DIKSLFRPFNMSCMDNVSILFADIVGFTRMSS 372
FRPF M ++ VSILFADIVGFT+MS+
Sbjct: 377 KAPIAFRPFKMQQIEEVSILFADIVGFTKMSA 408
Score = 114 bits (274), Expect = 9e-24
Identities = 51/83 (61%), Positives = 66/83 (79%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI++F +E+ E +NMRVGVHTGTVLCGI+G RRFKFDVWSNDV AN ME G G+
Sbjct: 469 MIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGK 528
Query: 433 VHISEETSQFLGGSYILEEGEEV 455
VHISE T+++L Y +E+G+ +
Sbjct: 529 VHISEATAKYLDDRYEMEDGKVI 551
Score = 50.4 bits (115), Expect = 2e-04
Identities = 21/78 (26%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 367 FTRMSSMIEAIQEFDRER-GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKME 425
F M+ + +F+ +RVG + G + G++GT + +D+W + V A++M+
Sbjct: 1139 FEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMD 1198
Query: 426 SSGKPGRVHISEETSQFL 443
++G R+ +SEE+ + L
Sbjct: 1199 TTGVECRIQVSEESYRVL 1216
>UniRef50_A7RN58 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1100
Score = 165 bits (401), Expect = 4e-39
Identities = 111/326 (34%), Positives = 164/326 (50%), Gaps = 19/326 (5%)
Query: 57 IPIAFERAAPGTWWNPRFDSEILEGQYRSSSFRQIRLRFRFALLYILIFSISWFVYFVVL 116
IP+ FERA+ WWNP FDS+ILE +++ +F + R AL +IL + +W ++F
Sbjct: 1 IPLFFERAS-SKWWNPSFDSKILEEEFQRFTFTHNKRRLIRALFFILAAAGAWAIFFGAF 59
Query: 117 GLNDVTVKWPFLCSLFAGVLLITCIMLLVTFTNFYKVYTFKLSLVMAXXXXXXXXXXXXX 176
++ T W L ++++ ++L + N YK +SL +
Sbjct: 60 -YSERTHYWKILLGDLVFMIVVAALILFTKYCNLYKKCAAYISLFTSLWLITAELATYT- 117
Query: 177 XXXXXXXFYQAADISQSGHFTMCI-EXXXXXXXXXXXXXXACVILGIIYSIVFEVLNIVL 235
F + + S + F++C C+ + + +SI EVL
Sbjct: 118 -------FLE--EFSITARFSVCTCFILVIYTMLHSLRLYICIFITVAFSIAHEVLYAFF 168
Query: 236 HLSE-QEWQASGMFVR--ILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEME 292
S+ Q + G + +LL C+H+IG+ I+ M VR R TF KVGQS + RR LE+E
Sbjct: 169 GNSKGQRLKGQGEEIASIVLLHACIHLIGISIFFMAQVRERSTFWKVGQSYVARRDLEIE 228
Query: 293 KQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMS 352
KQ+KE+MI SVMP +A +L+N V + D N K + K +FRPF M
Sbjct: 229 KQVKERMIRSVMPEIVADSLLN--VDDEDEN-KNGNGREMGNGKRKHKKAKMVFRPFQMH 285
Query: 353 CMDNVSILFADIVGFTRMSSMIEAIQ 378
M+NVSILFADIVGFT+MSS A Q
Sbjct: 286 RMENVSILFADIVGFTKMSSNKSADQ 311
Score = 126 bits (304), Expect = 2e-27
Identities = 61/101 (60%), Positives = 74/101 (73%), Gaps = 6/101 (5%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+E I+EFD + ++MRVGVHTGTVLCGIVGT+RFKFDVWSNDVT AN+ME++G PGR
Sbjct: 366 MLEQIKEFDNDTDNDVDMRVGVHTGTVLCGIVGTKRFKFDVWSNDVTLANRMETAGLPGR 425
Query: 433 VHISEETSQFLGGSYILEEGE------EVFGHKTYFIEGRQ 467
VHI+E T FL YI+E G + G TYFI GR+
Sbjct: 426 VHITEATVGFLRDQYIVENGHGETRNAALKGITTYFIVGRK 466
Score = 61.3 bits (142), Expect = 9e-08
Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 373 MIEAIQEFDRER-GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
M + F+ G +R+G + G V G++GT + +D+W + V A++M+S+G P
Sbjct: 996 MFNVVDRFNEHMLGFKFKLRIGFNAGPVTAGVIGTTKLLYDIWGDTVNLASRMDSTGVPE 1055
Query: 432 RVHISEETSQFLGGSYILE 450
++ +SE T + L +I E
Sbjct: 1056 KIQVSESTKEMLNDFFIFE 1074
>UniRef50_Q19523 Cluster: Putative uncharacterized protein acy-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acy-1 - Caenorhabditis elegans
Length = 1253
Score = 162 bits (393), Expect = 3e-38
Identities = 107/325 (32%), Positives = 161/325 (49%), Gaps = 30/325 (9%)
Query: 57 IPIAFERAAPGTWWNPRFDSEILEGQYRSSSFRQIRLRFRFALLYILIFSISWFVYFVVL 116
+P+ FERA+ WWNP+F S LE QY SF Q+R RFR L+YI + +W +Y +
Sbjct: 30 VPL-FERAS-ARWWNPQFRSATLEAQYWKCSFSQLRDRFRSGLIYIAVVIAAWTLYLALF 87
Query: 117 GLNDVTVKWPFLCSLFAGVLLITCIMLLVTFTNFYKVYTFKLSLVMAXXXXXXXXXXXXX 176
+ LC + + FY +F + ++
Sbjct: 88 DRTFIQHWIVSLCLCAIIFAMFAFTACAAQYQRFYMPTSFLCTFLICLVTLLIFSAEN-- 145
Query: 177 XXXXXXXFYQAADISQSGHFTMCIEXXXXXXXXXXXXXXACVILGIIYSIVFEVLNIVLH 236
QAA ++ + C+++GIIYSI+FE+LN
Sbjct: 146 ---------QAAFMTPVASLATSFQVVLLIYTVIPLPLYLCILIGIIYSILFEILN---- 192
Query: 237 LSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLK 296
++ + +G +++++L VH++GVH++++T VR R TF+KVGQS+L R+ LE+E Q K
Sbjct: 193 KNKIGLEEAG-YIKLVLHAGVHLLGVHLFILTQVRQRKTFLKVGQSMLARKDLELETQFK 251
Query: 297 EKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSL---------FR 347
+ MI SVMP K+A L+ + ++ + N N R SN + L FR
Sbjct: 252 DHMIQSVMPKKVADELLKD---ASELRRPSASNDSNCRTSNATQVDQPLAKMVPEYRKFR 308
Query: 348 PFNMSCMDNVSILFADIVGFTRMSS 372
PF M+ M NVSILFADI GFT+MSS
Sbjct: 309 PFTMNLMTNVSILFADIAGFTKMSS 333
Score = 122 bits (294), Expect = 3e-26
Identities = 55/95 (57%), Positives = 74/95 (77%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI AI++FD +RG+ +NMRVG+HTG V+CG+VGT+RFKFDV+SNDVT AN+MESSG GR
Sbjct: 394 MIVAIRQFDIDRGQEVNMRVGIHTGKVMCGMVGTKRFKFDVFSNDVTLANEMESSGVAGR 453
Query: 433 VHISEETSQFLGGSYILEEGEEVFGHKTYFIEGRQ 467
VH+SE T++ L G Y +EEG + G ++G +
Sbjct: 454 VHVSEATAKLLKGLYEIEEGPDYDGPLRMQVQGTE 488
Score = 52.0 bits (119), Expect = 5e-05
Identities = 24/83 (28%), Positives = 46/83 (55%), Gaps = 6/83 (7%)
Query: 391 RVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYILE 450
++G++ G V G++GT + +D+W + V A++M S+G R+ +S+ T ++L Y E
Sbjct: 1155 KLGLNIGPVTAGVIGTTKLYYDIWGDTVNIASRMYSTGVLNRIQVSQHTREYLLDRYEFE 1214
Query: 451 EGEEV------FGHKTYFIEGRQ 467
+ + G TY + GR+
Sbjct: 1215 FRDHIEVKGIDGGMDTYLLVGRK 1237
>UniRef50_UPI0000E49494 Cluster: PREDICTED: similar to adenylyl
cyclase type IX; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to adenylyl cyclase type IX -
Strongylocentrotus purpuratus
Length = 1073
Score = 140 bits (340), Expect = 9e-32
Identities = 66/100 (66%), Positives = 79/100 (79%), Gaps = 5/100 (5%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SMIEAI++F E GE +NMRVG+HTGTVLCGIVG RRFKFDVWSNDVT ANKME+SG+PG
Sbjct: 287 SMIEAIKDFCHETGEKVNMRVGIHTGTVLCGIVGNRRFKFDVWSNDVTIANKMEASGQPG 346
Query: 432 RVHISEETSQFLGGSYILEEGEE-----VFGHKTYFIEGR 466
+VH+S E+ +FL Y+L+EG + G KTYFI GR
Sbjct: 347 KVHVSAESIKFLKERYVLDEGNADKHALLIGMKTYFIAGR 386
Score = 99 bits (238), Expect = 2e-19
Identities = 53/140 (37%), Positives = 90/140 (64%), Gaps = 10/140 (7%)
Query: 233 IVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEME 292
++ L E A+ +F ++ L LC+H++G+HI+ M+ VR R TF+KV ++++ + + E
Sbjct: 98 LLASLQPDEVNATHVFTKLFLHLCIHMMGMHIFFMSQVRNRSTFLKVVETVVAQNLHKRE 157
Query: 293 KQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMS 352
KQ+KE I S+MP +A L+ + E++ V+ + + R S+ + +FRPF M+
Sbjct: 158 KQIKEATIQSLMPDTIAKELLKGR--ESNPEVRPH---IGRRQSS-----EPIFRPFYMN 207
Query: 353 CMDNVSILFADIVGFTRMSS 372
M+NVSIL+ADI GFT+MS+
Sbjct: 208 RMENVSILYADIAGFTKMSA 227
Score = 56.4 bits (130), Expect = 2e-06
Identities = 27/64 (42%), Positives = 43/64 (67%), Gaps = 5/64 (7%)
Query: 44 ARNNSTTNCCGLTIPIAFERAAPGTWWNPRFDSEILEGQYRSSSFRQIRLRFRFALLYIL 103
+R + + CC P FERA+ G+WW+P+F+ I+E Q++ SF Q++ RFR+AL Y L
Sbjct: 44 SRRSLSGRCC----PKLFERAS-GSWWDPKFNLPIIEEQFQVHSFPQLKKRFRYALGYAL 98
Query: 104 IFSI 107
+ S+
Sbjct: 99 LASL 102
Score = 55.2 bits (127), Expect = 6e-06
Identities = 22/66 (33%), Positives = 40/66 (60%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYIL 449
+R+G + G + G++GT + +D+W + V A++M+S+G PG V ++E + L Y
Sbjct: 983 LRIGYNHGKLTSGVIGTTKLLYDIWGDTVNVASRMDSTGMPGHVQVTEHSMTVLEPYYEF 1042
Query: 450 EEGEEV 455
E+ EV
Sbjct: 1043 EKRGEV 1048
>UniRef50_Q5BXY8 Cluster: SJCHGC07735 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07735 protein - Schistosoma
japonicum (Blood fluke)
Length = 228
Score = 119 bits (287), Expect = 2e-25
Identities = 54/84 (64%), Positives = 66/84 (78%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M AIQ+FD + E +NMRVGVHTG V+CGIVGT+RFKFDVWSNDVT AN+MESSG+ G
Sbjct: 48 AMCLAIQQFDEDHSEEVNMRVGVHTGKVICGIVGTKRFKFDVWSNDVTLANEMESSGEAG 107
Query: 432 RVHISEETSQFLGGSYILEEGEEV 455
+VHISE T F+ Y + EG+ V
Sbjct: 108 KVHISEATLSFVKDIYEVSEGKPV 131
>UniRef50_Q4RZV3 Cluster: Chromosome 18 SCAF14786, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 18
SCAF14786, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 576
Score = 110 bits (264), Expect = 1e-22
Identities = 49/73 (67%), Positives = 60/73 (82%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI++F +E E ++MRVGVHTGTVLCGI+G +RFKFDVWSNDV AN ME G G+
Sbjct: 481 MIQAIEQFCQETRETVSMRVGVHTGTVLCGILGMKRFKFDVWSNDVNLANLMEQLGVAGK 540
Query: 433 VHISEETSQFLGG 445
VH+SE T+QFLGG
Sbjct: 541 VHLSEATAQFLGG 553
Score = 93.1 bits (221), Expect = 2e-17
Identities = 52/145 (35%), Positives = 82/145 (56%), Gaps = 19/145 (13%)
Query: 190 ISQSGHFTMCIEXXXXXXXXXXXXXXACVILGIIYSIVFEVLNIVLHL------------ 237
IS G F++C+E A V+LG +YS++FE L + L
Sbjct: 186 ISPVGTFSLCMEVLLLLYSVLHVRLYASVMLGFLYSVLFEALEWLPLLQRSYETAGWQTE 245
Query: 238 ---SEQEWQASGMF----VRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLE 290
S +W+ + + LL LC H+IG+H+++M+ VR R TF+KVGQ+++ + LE
Sbjct: 246 SDPSGSDWEGHTLRWLGPAKALLHLCAHVIGIHLFIMSEVRSRSTFLKVGQAIMHGKDLE 305
Query: 291 MEKQLKEKMIHSVMPPKLASNLMNE 315
+EK LKE+MIHSVMP ++A +L+ +
Sbjct: 306 VEKALKERMIHSVMPRRVADDLLRQ 330
Score = 49.6 bits (113), Expect = 3e-04
Identities = 26/47 (55%), Positives = 33/47 (70%), Gaps = 2/47 (4%)
Query: 326 TYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSS 372
T++N + S P I +FRPFNM M+ VSILFADIVGFT+MS+
Sbjct: 376 THNNHKCKKTSIPRGQI--IFRPFNMKRMEPVSILFADIVGFTKMSA 420
>UniRef50_Q4T7J2 Cluster: Chromosome undetermined SCAF8089, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF8089, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 821
Score = 105 bits (252), Expect = 4e-21
Identities = 53/131 (40%), Positives = 81/131 (61%), Gaps = 8/131 (6%)
Query: 339 GSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGT 398
G D+ + R + + ++ +LF ++ ++R + + G I+MRVGVHTG
Sbjct: 126 GLDMCTAIRCVSFMVLSSLGLLF--LLSWSRNNDFPCGCSKLREATGVEISMRVGVHTGN 183
Query: 399 VLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYILEEGEE---- 454
VLCG++G +++++DVWS+DVT AN MES G PGRVHI+EET Q L G+Y +EE +
Sbjct: 184 VLCGVIGLQKWQYDVWSHDVTLANHMESGGLPGRVHITEETLQHLNGAYQVEESDGASRD 243
Query: 455 --VFGHKTYFI 463
+ G KTY +
Sbjct: 244 PLLHGRKTYLV 254
Score = 58.0 bits (134), Expect = 8e-07
Identities = 20/54 (37%), Positives = 39/54 (72%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+R+G++ G V+ G++G + ++D+W N V A++MES+G ++ ++EETSQ +
Sbjct: 736 LRIGINHGPVIAGVIGAHKPQYDIWGNSVNVASRMESTGVLDKIQVTEETSQMV 789
>UniRef50_Q6WIQ8 Cluster: Adenylate cyclase type VII; n=2;
Xenopus|Rep: Adenylate cyclase type VII - Xenopus laevis
(African clawed frog)
Length = 667
Score = 104 bits (250), Expect = 7e-21
Identities = 44/78 (56%), Positives = 62/78 (79%)
Query: 375 EAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVH 434
E+I++ G INMRVGVH+G VLCG++G R+++FDVWS+DV+ AN+MES+G PGRVH
Sbjct: 247 ESIKQVREATGADINMRVGVHSGNVLCGVIGLRKWQFDVWSHDVSLANRMESAGLPGRVH 306
Query: 435 ISEETSQFLGGSYILEEG 452
I+E T + + G+Y +EEG
Sbjct: 307 ITEATLKHMNGAYDVEEG 324
Score = 49.6 bits (113), Expect = 3e-04
Identities = 42/156 (26%), Positives = 80/156 (51%), Gaps = 16/156 (10%)
Query: 218 VILGIIYSIVFEVLNIVLHLSEQEWQASGMFVRILLQLCVHIIGV-HIYLMTFVRMRGTF 276
+I GI + IV + +VL + A + ++ LC +++G H Y M R +
Sbjct: 44 IISGISHIIVISI-TVVLCSGSNDAIAFQLIANAVIFLCGNLMGAYHKYHMQDAS-RDLY 101
Query: 277 MKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRIS 336
+ + ++ +LE++K+ +E ++ SV+P ++ M +++ D +T N
Sbjct: 102 SYTVKCIRIKMKLELKKRQQESLLLSVLPVYIS---MGDELAIQDRLTETNDN------R 152
Query: 337 NPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSS 372
P ++ +L+ + NVSIL+ADIVGFTR++S
Sbjct: 153 QPDNNFTALY----VKRHQNVSILYADIVGFTRLAS 184
>UniRef50_Q966F9 Cluster: Adenylyl cyclase protein 4; n=2;
Caenorhabditis|Rep: Adenylyl cyclase protein 4 -
Caenorhabditis elegans
Length = 954
Score = 103 bits (247), Expect = 2e-20
Identities = 48/96 (50%), Positives = 67/96 (69%), Gaps = 2/96 (2%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MIEAI+ +NMRVG+HTG CG++G ++++FDVWSNDVT AN+MES G GR
Sbjct: 318 MIEAIRLVREMTLVNVNMRVGIHTGKAHCGVLGLKKWQFDVWSNDVTLANQMESGGLAGR 377
Query: 433 VHISEETSQFLGGSYILEEGEEVFGHKTYFIEGRQV 468
VHI++ T +L G+YILEEG G ++ F+E ++
Sbjct: 378 VHITDATRSYLKGAYILEEGNG--GSRSKFLEKEKI 411
Score = 58.4 bits (135), Expect = 6e-07
Identities = 20/55 (36%), Positives = 37/55 (67%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
N+R+G++ G V+ G++G+ + +D+W N V A++M+S G GR+ ++EE L
Sbjct: 862 NLRIGINVGPVVAGVIGSDKPHYDIWGNSVNVASRMDSGGVAGRIQVTEEVKSIL 916
Score = 39.9 bits (89), Expect = 0.23
Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 24/160 (15%)
Query: 216 ACVILGIIYSIVFEVLNIVLHLSEQEWQASGMFV---RILLQLCVHIIGVHIYLMTFVRM 272
+CVI+ S+ V +++ + S M + R+++ + V+++G +Y T
Sbjct: 119 SCVIISACTSMRTSVTYLLIFSTYSLLPMSFMLMILTRVMMVILVNVVGSLVYYPTEFVQ 178
Query: 273 RGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLN 332
R TF + + + R L+ E +EK++ +V+P +A E +++ H
Sbjct: 179 RKTFHETRKCVQSRMLLDKEMHRQEKILLAVLPKNIA--------FEVKKDMQETHE--- 227
Query: 333 SRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSS 372
+ +F + +++SILFADI GFT ++S
Sbjct: 228 ----------ERMFHKIYIRKYEDISILFADICGFTNLAS 257
>UniRef50_Q5MAL2 Cluster: Adenylate cyclase; n=1; Aplysia
californica|Rep: Adenylate cyclase - Aplysia californica
(California sea hare)
Length = 1246
Score = 102 bits (245), Expect = 3e-20
Identities = 43/80 (53%), Positives = 61/80 (76%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M++AI++ G ++MR+GVHTG+VLCG++G R++++DVWS+DVT AN MES G PGR
Sbjct: 533 MLDAIRDVRENTGVDVDMRIGVHTGSVLCGVLGLRKWQYDVWSDDVTIANNMESGGVPGR 592
Query: 433 VHISEETSQFLGGSYILEEG 452
VHIS++T L G Y +E G
Sbjct: 593 VHISKQTLDCLDGEYDVEPG 612
Score = 64.1 bits (149), Expect = 1e-08
Identities = 23/72 (31%), Positives = 48/72 (66%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M+ + ++ ++R+GV+ G V+ G++G R+ ++D+W + V A++M+SSG+PG
Sbjct: 1139 AMMSTLDTVNQHSFNNFSLRIGVNHGPVIAGVIGARKPQYDIWGDTVNVASRMDSSGEPG 1198
Query: 432 RVHISEETSQFL 443
++ + EET+ L
Sbjct: 1199 KIQMREETAAVL 1210
Score = 38.7 bits (86), Expect = 0.53
Identities = 42/153 (27%), Positives = 68/153 (44%), Gaps = 18/153 (11%)
Query: 226 IVFEVLNIVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLV 285
IVF +L L + +F L+ +IIG+ ++ V R F+ S+
Sbjct: 344 IVFHLLTAGLCSTTHSDLGLQLFCNFLVLSSANIIGLTHKFLSDVAHRRAFLDARNSVDS 403
Query: 286 RRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSL 345
+LE EKQ +++++ S +P SNL+ E + N+ R P +L
Sbjct: 404 MIKLEKEKQQQDELLVSCIP----SNLVKEIKKDLQENM---------REPRP-----TL 445
Query: 346 FRPFNMSCMDNVSILFADIVGFTRMSSMIEAIQ 378
F + VSIL+ADIV FT ++S A +
Sbjct: 446 FHDLYVQRYHGVSILYADIVNFTPLASECTAAE 478
>UniRef50_Q9VW60 Cluster: Adenylate cyclase type 2; n=2;
Sophophora|Rep: Adenylate cyclase type 2 - Drosophila
melanogaster (Fruit fly)
Length = 1307
Score = 102 bits (245), Expect = 3e-20
Identities = 43/81 (53%), Positives = 61/81 (75%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI+ G ++MR+G+HTG VLCG++G R+++FDVWS+DVT AN MES G GR
Sbjct: 392 MIDAIRHVREATGINVDMRIGIHTGNVLCGVLGLRKWQFDVWSDDVTLANHMESGGVAGR 451
Query: 433 VHISEETSQFLGGSYILEEGE 453
VHI+++T FLG + +E+GE
Sbjct: 452 VHITKQTLDFLGDKFEVEQGE 472
Score = 60.1 bits (139), Expect = 2e-07
Identities = 22/72 (30%), Positives = 47/72 (65%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+++ + +RE + +R+G++ G V+ G++G ++ ++D+WSN V A++M+S G G
Sbjct: 1202 ALMSILDSINRESFQRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVASRMDSCGVMG 1261
Query: 432 RVHISEETSQFL 443
R+ +E T++ L
Sbjct: 1262 RLQTTENTAKIL 1273
Score = 40.7 bits (91), Expect = 0.13
Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 247 MFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPP 306
+F I++ + G++ +M+ T + R +LE E++ +E+++ SV+P
Sbjct: 214 LFGEIVMLASASVSGLYYRIMSDAAHNRTVDGTRTGIEQRVKLECEREQQEQLLLSVIPA 273
Query: 307 KLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVG 366
+A+ E ++ R S + F ++ NV+ILFADIV
Sbjct: 274 YIAA--------EVKRSIMLKMADACQRAGGQASTSATRFHELHVQRHTNVTILFADIVN 325
Query: 367 FTRMSSMIEA 376
FT +SS + A
Sbjct: 326 FTPLSSSLTA 335
>UniRef50_Q4RVX9 Cluster: Chromosome 9 SCAF14991, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 9
SCAF14991, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1208
Score = 102 bits (244), Expect = 4e-20
Identities = 44/80 (55%), Positives = 59/80 (73%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MIEAI G +NMRVG+H+G V CG++G R+++FDVWSNDVT AN+ME+ GK GR
Sbjct: 460 MIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANQMEAGGKAGR 519
Query: 433 VHISEETSQFLGGSYILEEG 452
+HI++ T Q+L G Y +E G
Sbjct: 520 IHITKATLQYLNGDYEVEPG 539
Score = 50.8 bits (116), Expect = 1e-04
Identities = 17/64 (26%), Positives = 39/64 (60%)
Query: 375 EAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVH 434
E ++ + M++G++ G V+ G++G R+ ++D+W N V A++M+S+G P +
Sbjct: 1108 EQMKYINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDYIQ 1167
Query: 435 ISEE 438
++ +
Sbjct: 1168 VTTD 1171
>UniRef50_UPI0000D5745B Cluster: PREDICTED: similar to CG32158-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG32158-PB, isoform B - Tribolium castaneum
Length = 1333
Score = 101 bits (243), Expect = 5e-20
Identities = 45/80 (56%), Positives = 58/80 (72%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI +NMRVG+HTG V CG++G R+++FDVWSNDVT AN MES G PGR
Sbjct: 616 MIDAIALVREVMSVNVNMRVGIHTGRVHCGVLGLRKWQFDVWSNDVTLANHMESGGIPGR 675
Query: 433 VHISEETSQFLGGSYILEEG 452
VHI++ET + LG Y++E G
Sbjct: 676 VHITKETLKCLGNDYVVEPG 695
Score = 58.4 bits (135), Expect = 6e-07
Identities = 30/98 (30%), Positives = 56/98 (57%), Gaps = 6/98 (6%)
Query: 375 EAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVH 434
E + E + +R+G++ G V+ G++G R+ ++D+W N V A++M+S+G ++
Sbjct: 1194 EQLAEVNEHSFNHFRIRIGINVGPVVAGVIGARKPQYDIWGNAVNVASRMDSTGVLDKIQ 1253
Query: 435 ISEETSQFLG--GSYILEEGE-EVFGH---KTYFIEGR 466
+++E Q L G + G +V G +TYF+EGR
Sbjct: 1254 VTKEVYQILSSRGYPLTCRGTIQVKGKGTMETYFLEGR 1291
>UniRef50_UPI00015A564B Cluster: Novel protein similar to vertebrate
adenylate cyclase 2 (Brain) (ADCY2); n=2; Danio
rerio|Rep: Novel protein similar to vertebrate adenylate
cyclase 2 (Brain) (ADCY2) - Danio rerio
Length = 793
Score = 101 bits (243), Expect = 5e-20
Identities = 44/80 (55%), Positives = 60/80 (75%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M EAI++ G INMRVGVH+G VLCG++G +++++DVWS+DVT AN ME+ G PGR
Sbjct: 125 MCEAIEKVREATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGR 184
Query: 433 VHISEETSQFLGGSYILEEG 452
VHIS T + L G+Y +E+G
Sbjct: 185 VHISSVTLEHLNGAYKVEQG 204
Score = 60.1 bits (139), Expect = 2e-07
Identities = 22/72 (30%), Positives = 46/72 (63%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+++ + ++ MRVG++ G V+ G++G ++ ++D+W N V A++MES+G G
Sbjct: 696 ALVGKLDVINKHSFNDFRMRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMESTGVLG 755
Query: 432 RVHISEETSQFL 443
++ ++EET+ L
Sbjct: 756 KIQVTEETNWIL 767
>UniRef50_UPI000155CC3E Cluster: PREDICTED: similar to adenylate
cyclase 7; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to adenylate cyclase 7 - Ornithorhynchus
anatinus
Length = 816
Score = 101 bits (241), Expect = 9e-20
Identities = 53/117 (45%), Positives = 73/117 (62%), Gaps = 4/117 (3%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M EAI++ G I+MRVG+H+G VLCG++G R++++DVWS+DV+ AN+MES+G PGR
Sbjct: 496 MCEAIKQVKEATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMESAGVPGR 555
Query: 433 VHISEETSQFLGGSYILEEGEEVFGH---KTYFIEGRQVFCPYDREQCLTPSNPVNL 486
VHI+E T L Y +EEG K I+ V P R Q L P++P L
Sbjct: 556 VHITEATLSHLDKEYEVEEGNGQLRDAYLKEMNIQTYLVIDPRQRRQPL-PTHPQQL 611
>UniRef50_Q5TUN5 Cluster: ENSANGP00000027378; n=2; Culicidae|Rep:
ENSANGP00000027378 - Anopheles gambiae str. PEST
Length = 2040
Score = 101 bits (241), Expect = 9e-20
Identities = 44/80 (55%), Positives = 58/80 (72%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI + +NMRVG+H+G VLCG++G R+++FDVWSNDVT AN MES G+PGR
Sbjct: 350 MIDAIASVVEQTDVILNMRVGIHSGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGR 409
Query: 433 VHISEETSQFLGGSYILEEG 452
VH++ T LGG Y +E G
Sbjct: 410 VHVTRATLDALGGEYEVEAG 429
Score = 60.5 bits (140), Expect = 2e-07
Identities = 27/88 (30%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 360 LFADIVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVT 419
L +V F + +M ++ + +RVGV+ G V+ G++G R+ ++D+W N V
Sbjct: 1037 LMTALVDFVK--AMRVTLKNINENSYNNFMLRVGVNVGPVVAGVIGARKPQYDIWGNTVN 1094
Query: 420 FANKMESSGKPGRVHISEETSQFLGGSY 447
A++M+S+G PG +++E L GS+
Sbjct: 1095 VASRMDSTGIPGYTQVTQEVVDSLQGSH 1122
Score = 38.7 bits (86), Expect = 0.53
Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 23/126 (18%)
Query: 257 VHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQ 316
V++ G + +M R F+ + R ++E E + E+++ SV+P +A + N+
Sbjct: 196 VNVAGFVVNVMMERAQRRAFLDTRNCIAARLEMEDENEKLERLLLSVLPQHVAMEMKNDI 255
Query: 317 VTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
+ S ++ F + +NVSILFADIVGFT ++S A
Sbjct: 256 L----------------------SPVEGQFHKIYIQKHENVSILFADIVGFTVLASQCSA 293
Query: 377 IQEFDR 382
QE R
Sbjct: 294 -QELVR 298
>UniRef50_Q4T405 Cluster: Chromosome 8 SCAF9864, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF9864, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 879
Score = 100 bits (239), Expect = 2e-19
Identities = 43/81 (53%), Positives = 61/81 (75%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M EAI++ G INMRVGVH+G VLCG++G +++++DVWS+DVT AN ME+ G PGR
Sbjct: 304 MCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGR 363
Query: 433 VHISEETSQFLGGSYILEEGE 453
VHI+ T + L G+Y +E+G+
Sbjct: 364 VHITSVTLEHLNGAYKVEDGD 384
Score = 61.3 bits (142), Expect = 9e-08
Identities = 22/72 (30%), Positives = 47/72 (65%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+++ + ++ +RVG++ G V+ G++G ++ ++D+W N V A++MES+G G
Sbjct: 768 ALVGKLDVINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMESTGVLG 827
Query: 432 RVHISEETSQFL 443
++ ++EETS+ L
Sbjct: 828 KIQVTEETSRIL 839
>UniRef50_O95622 Cluster: Adenylate cyclase type 5; n=41;
Deuterostomia|Rep: Adenylate cyclase type 5 - Homo
sapiens (Human)
Length = 1261
Score = 99.5 bits (237), Expect = 3e-19
Identities = 43/80 (53%), Positives = 57/80 (71%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MIEAI G +NMRVG+H+G V CG++G R+++FDVWSNDVT AN ME+ GK GR
Sbjct: 544 MIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGR 603
Query: 433 VHISEETSQFLGGSYILEEG 452
+HI++ T +L G Y +E G
Sbjct: 604 IHITKATLNYLNGDYEVEPG 623
Score = 56.8 bits (131), Expect = 2e-06
Identities = 22/79 (27%), Positives = 48/79 (60%), Gaps = 1/79 (1%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
+++ ++ + M++G++ G V+ G++G R+ ++D+W N V A++M+S+G P R
Sbjct: 1158 LMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDR 1217
Query: 433 VHISEETSQFL-GGSYILE 450
+ ++ + Q L +Y LE
Sbjct: 1218 IQVTTDMYQVLAANTYQLE 1236
Score = 49.2 bits (112), Expect = 4e-04
Identities = 45/162 (27%), Positives = 75/162 (46%), Gaps = 24/162 (14%)
Query: 216 ACVILGIIYSIVFEVLNIVLHLSEQE-WQASGMFVRILLQLCVHIIGVHIYLMTFVRMRG 274
A V+ G++ S + L I L + Q+ + + +L+ C +I+GV + V R
Sbjct: 349 AAVLSGVLLSALH--LAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQ 406
Query: 275 TFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSR 334
F + + + R + E Q +E+++ SV+P +A + +AD N K
Sbjct: 407 AFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEM------KADINAKQ-------- 452
Query: 335 ISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
D+ +F + DNVSILFADI GFT ++S A
Sbjct: 453 -----EDM--MFHKIYIQKHDNVSILFADIEGFTSLASQCTA 487
>UniRef50_O96306 Cluster: Adenylyl cyclase isoform DAC39E; n=7;
Diptera|Rep: Adenylyl cyclase isoform DAC39E -
Drosophila melanogaster (Fruit fly)
Length = 1167
Score = 99.1 bits (236), Expect = 4e-19
Identities = 51/100 (51%), Positives = 70/100 (70%), Gaps = 8/100 (8%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SM++AI+ ++ ++MRVG+HTG VL GI+G R+++FDV+S DV ANKMESSGK G
Sbjct: 377 SMVKAIKYVQQKANSPVDMRVGIHTGAVLAGILGQRQWQFDVYSKDVELANKMESSGKAG 436
Query: 432 RVHISEETSQFLGGSYILEE--GEE------VFGHKTYFI 463
RVHIS++T FL G + +E GE+ + G KTYFI
Sbjct: 437 RVHISDKTLAFLNGEFEVEAAFGEKREELLRIAGLKTYFI 476
Score = 59.7 bits (138), Expect = 3e-07
Identities = 22/68 (32%), Positives = 42/68 (61%)
Query: 376 AIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHI 435
A+Q + + +++G++ G + G++G R+ +D+W N V A++MES+GK G + +
Sbjct: 997 ALQSINEQSFNHFVLKMGINHGPITAGVIGARKPHYDIWGNTVNVASRMESTGKAGAIQV 1056
Query: 436 SEETSQFL 443
+EET L
Sbjct: 1057 TEETCNIL 1064
Score = 45.6 bits (103), Expect = 0.005
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 25/162 (15%)
Query: 218 VILGIIYSIVFEVLNIVLHLSEQEWQA---SGMFVRILLQLCVHIIGVHIYLMTFVRMRG 274
+ LG+ + + + L + W + + + +L +IG+ Y M + +
Sbjct: 182 IFLGLSIGCITYFICLSLPVGYSHWDSLLSNQLAANAVLIATAALIGLLYYFMGEAKQKR 241
Query: 275 TFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSR 334
F++ +SL V+ +E + +E+++ SV+P +A M E +
Sbjct: 242 AFLEAKKSLEVKMVIEEQSAEQERLLLSVLPKHVAIK-MREDL----------------- 283
Query: 335 ISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
GS F+ MS +NVSIL+ADIVGFT +SS A
Sbjct: 284 ----GSSSSEAFKKIYMSRHENVSILYADIVGFTAISSTYSA 321
>UniRef50_Q6PG12 Cluster: Adcy3 protein; n=13; Euteleostomi|Rep:
Adcy3 protein - Mus musculus (Mouse)
Length = 1005
Score = 98.7 bits (235), Expect = 5e-19
Identities = 44/82 (53%), Positives = 60/82 (73%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M+EAI + G++MRVGVHTGTVL G++G +R+++DVWS DVT ANKME+ G PG
Sbjct: 393 AMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPG 452
Query: 432 RVHISEETSQFLGGSYILEEGE 453
RVHIS+ T L G + +E G+
Sbjct: 453 RVHISQSTMDCLKGEFDVEPGD 474
Score = 60.9 bits (141), Expect = 1e-07
Identities = 47/165 (28%), Positives = 79/165 (47%), Gaps = 24/165 (14%)
Query: 218 VILGIIYSIVFEVLNIVLHLSEQEWQASGM------FVRILLQLCVHIIGVHIYLMTFVR 271
VI+ ++ +V ++ V +Q+ + GM + L LC I+G+ Y M +
Sbjct: 191 VIISVVSCVVHTLVLGVTVAQQQQDELEGMQLLREILANVFLYLCAIIVGIMSYYMADRK 250
Query: 272 MRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPL 331
R F++ QSL V+ LE + Q +E ++ S++P +A ++ + + D + K
Sbjct: 251 HRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDM--KKDESQKD----- 303
Query: 332 NSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
+ F M +NVSILFADIVGFT++SS A
Sbjct: 304 -----------QQQFNTMYMYRHENVSILFADIVGFTQLSSACSA 337
>UniRef50_Q5MAL1 Cluster: Adenylate cyclase; n=1; Aplysia
californica|Rep: Adenylate cyclase - Aplysia californica
(California sea hare)
Length = 1085
Score = 98.7 bits (235), Expect = 5e-19
Identities = 44/81 (54%), Positives = 55/81 (67%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+EAI G +NMRVG+H+G V CG++G +++FDVWSNDVT AN MES G PG
Sbjct: 404 MVEAIALVRDLTGTNVNMRVGIHSGRVHCGVLGLYKWQFDVWSNDVTLANHMESGGLPGH 463
Query: 433 VHISEETSQFLGGSYILEEGE 453
VHIS T +L G Y LE G+
Sbjct: 464 VHISSATKDYLNGDYDLEPGD 484
Score = 54.8 bits (126), Expect = 8e-06
Identities = 18/54 (33%), Positives = 38/54 (70%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
MR+G++ G V+ G++G ++ +D+W N V A++M+S+G+P ++ ++ E + L
Sbjct: 990 MRIGLNIGPVVAGVIGAKKPHYDIWGNTVNVASRMDSTGEPNKIQVTAEMYRIL 1043
Score = 54.0 bits (124), Expect = 1e-05
Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 22/161 (13%)
Query: 216 ACVILGIIYSIVFEVLNIVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGT 275
A ++ G++ VF+V Q + + + + +CV++IGV+ + + R
Sbjct: 209 AALVSGVLLP-VFQVSLASNFNVSQSYVRDQVVANVFIYICVNVIGVYFHYPMEAQQREA 267
Query: 276 FMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRI 335
F++ + VR ++ E Q +E+++ SV+P +A + +AD
Sbjct: 268 FLETRNCISVRLAMQKENQKQERLLLSVLPRHVAMEM------KADI------------- 308
Query: 336 SNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
G+ +++F + DNVSILFADI GFT +SS A
Sbjct: 309 --AGNKKEAMFHKIYIQRHDNVSILFADICGFTALSSTCTA 347
>UniRef50_P32870 Cluster: Ca(2+)/calmodulin-responsive adenylate
cyclase; n=5; Coelomata|Rep:
Ca(2+)/calmodulin-responsive adenylate cyclase -
Drosophila melanogaster (Fruit fly)
Length = 2248
Score = 98.7 bits (235), Expect = 5e-19
Identities = 44/80 (55%), Positives = 56/80 (70%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI +NMRVG+HTG VLCG++G R+++FDVWSNDVT AN MES G+PGR
Sbjct: 350 MIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGR 409
Query: 433 VHISEETSQFLGGSYILEEG 452
VH++ T L G Y +E G
Sbjct: 410 VHVTRATLDSLSGEYEVEAG 429
Score = 62.9 bits (146), Expect = 3e-08
Identities = 25/78 (32%), Positives = 48/78 (61%)
Query: 370 MSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
+ +M ++QE + +RVG++ G V+ G++G R+ ++D+W N V A++M+S+G
Sbjct: 1052 VKAMRHSLQEINSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGV 1111
Query: 430 PGRVHISEETSQFLGGSY 447
PG +++E L GS+
Sbjct: 1112 PGYSQVTQEVVDSLVGSH 1129
Score = 41.9 bits (94), Expect = 0.057
Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 23/136 (16%)
Query: 247 MFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPP 306
+ I++ + V++ G+ + +M R TF+ + R +++ E + E+++ SV+P
Sbjct: 186 LIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQ 245
Query: 307 KLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVG 366
+A + N+ + S + F + +NVSILFADIVG
Sbjct: 246 HVAMQMKNDIL----------------------SPVAGQFHRIYIQKHENVSILFADIVG 283
Query: 367 FTRMSSMIEAIQEFDR 382
FT +SS A QE R
Sbjct: 284 FTVLSSQCSA-QELVR 298
>UniRef50_O60266 Cluster: Adenylate cyclase type 3; n=21;
Theria|Rep: Adenylate cyclase type 3 - Homo sapiens
(Human)
Length = 1144
Score = 98.7 bits (235), Expect = 5e-19
Identities = 44/82 (53%), Positives = 60/82 (73%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M+EAI + G++MRVGVHTGTVL G++G +R+++DVWS DVT ANKME+ G PG
Sbjct: 393 AMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPG 452
Query: 432 RVHISEETSQFLGGSYILEEGE 453
RVHIS+ T L G + +E G+
Sbjct: 453 RVHISQSTMDCLKGEFDVEPGD 474
Score = 59.3 bits (137), Expect = 3e-07
Identities = 46/165 (27%), Positives = 78/165 (47%), Gaps = 24/165 (14%)
Query: 218 VILGIIYSIVFEVLNIVLHLSEQEWQASGM------FVRILLQLCVHIIGVHIYLMTFVR 271
VI+ ++ +V ++ V +Q+ + GM + L LC +G+ Y M +
Sbjct: 191 VIISVVSCVVHTLVLGVTVAQQQQEELKGMQLLREILANVFLYLCAIAVGIMSYYMADRK 250
Query: 272 MRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPL 331
R F++ QSL V+ LE + Q +E ++ S++P +A ++ + + D + K
Sbjct: 251 HRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDM--KKDESQKD----- 303
Query: 332 NSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
+ F M +NVSILFADIVGFT++SS A
Sbjct: 304 -----------QQQFNTMYMYRHENVSILFADIVGFTQLSSACSA 337
Score = 59.3 bits (137), Expect = 3e-07
Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 8/124 (6%)
Query: 362 ADIVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFA 421
AD+ F +M + + + + +R+G++ G VL G++G R+ +D+W N V A
Sbjct: 1014 ADLADFAL--AMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVA 1071
Query: 422 NKMESSGKPGRVHISEETSQFLG--GSYILEEGEEVFGHK----TYFIEGRQVFCPYDRE 475
++MES+G G + + EET L G + G K T+F++GR +
Sbjct: 1072 SRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNG 1131
Query: 476 QCLT 479
+T
Sbjct: 1132 PSVT 1135
>UniRef50_UPI000155DD86 Cluster: PREDICTED: similar to adenylate
cyclase 7; n=1; Equus caballus|Rep: PREDICTED: similar
to adenylate cyclase 7 - Equus caballus
Length = 958
Score = 97.9 bits (233), Expect = 8e-19
Identities = 41/80 (51%), Positives = 61/80 (76%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M EAI++ G I+MRVG+H+G VLCG++G R++++DVWS+DV+ AN+ME++G PGR
Sbjct: 226 MCEAIKQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGR 285
Query: 433 VHISEETSQFLGGSYILEEG 452
VHI+E T L +Y +E+G
Sbjct: 286 VHITEATLNHLDKAYEVEDG 305
Score = 66.5 bits (155), Expect = 2e-09
Identities = 25/74 (33%), Positives = 48/74 (64%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+++ + +R +RVG++ G V+ G++G R+ ++D+W N V A++MES+G+ G
Sbjct: 848 ALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELG 907
Query: 432 RVHISEETSQFLGG 445
++ ++EETS L G
Sbjct: 908 KIQVTEETSAILQG 921
>UniRef50_Q4STI6 Cluster: Chromosome undetermined SCAF14199, whole
genome shotgun sequence; n=3; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14199,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 982
Score = 97.5 bits (232), Expect = 1e-18
Identities = 45/81 (55%), Positives = 58/81 (71%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M++AI + ++MRVGVHTGTVL G++G +R++FDVWS DVT ANKMES G PG
Sbjct: 392 AMVDAISYVREKTRTEVDMRVGVHTGTVLGGVLGQKRWQFDVWSTDVTLANKMESGGIPG 451
Query: 432 RVHISEETSQFLGGSYILEEG 452
RVHIS+ T L G + LE G
Sbjct: 452 RVHISQTTKDSLHGEFELEPG 472
Score = 57.6 bits (133), Expect = 1e-06
Identities = 37/130 (28%), Positives = 64/130 (49%), Gaps = 17/130 (13%)
Query: 247 MFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPP 306
+ ++L LC ++GV Y M + R F++ +SL V+ LE + +E+++ S++P
Sbjct: 224 LLASVMLYLCAAMVGVMSYYMADRKYRMAFLEARRSLEVKLTLEEQSTQQEELLLSILPK 283
Query: 307 KLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVG 366
+A ++ +A +++ F M +NVSILFADIVG
Sbjct: 284 HIADEMLQGMKNQAQQQ-----------------EVQQQFNTMYMYRHENVSILFADIVG 326
Query: 367 FTRMSSMIEA 376
FT++SS A
Sbjct: 327 FTQLSSACSA 336
Score = 56.0 bits (129), Expect = 3e-06
Identities = 22/72 (30%), Positives = 41/72 (56%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SM + +++ +R+G++ G VL G++G R+ +D+W N V A++MES+G G
Sbjct: 860 SMKVTLNNLNKQSFNNFMLRIGINKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMG 919
Query: 432 RVHISEETSQFL 443
+ + E+ L
Sbjct: 920 NIQVVEDCYDIL 931
>UniRef50_UPI00005A2FB4 Cluster: PREDICTED: similar to brain
adenylate cyclase 1; n=1; Canis lupus familiaris|Rep:
PREDICTED: similar to brain adenylate cyclase 1 - Canis
familiaris
Length = 1161
Score = 97.1 bits (231), Expect = 1e-18
Identities = 45/87 (51%), Positives = 59/87 (67%), Gaps = 3/87 (3%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+ I +NMRVG+HTG VLCG++G R++++DVWSNDVT AN ME++G PG+
Sbjct: 303 MIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGK 362
Query: 433 VHISEETSQFLGGSYILEEGEEVFGHK 459
VHI+ T L G Y +EEG GHK
Sbjct: 363 VHITRTTLACLNGDYEVEEGH---GHK 386
Score = 67.3 bits (157), Expect = 1e-09
Identities = 34/100 (34%), Positives = 58/100 (58%), Gaps = 6/100 (6%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M + + E + + +RVG++ G V+ G++G RR ++D+W N V A++M+S+G GR
Sbjct: 988 MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR 1047
Query: 433 VHISEETSQFL-GGSY--ILEEGEEVFGH---KTYFIEGR 466
+ ++EE + L G+Y + V G TYF+EGR
Sbjct: 1048 IQVTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGR 1087
>UniRef50_Q16XH3 Cluster: Adenylate cyclase; n=3; Endopterygota|Rep:
Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
Length = 1285
Score = 97.1 bits (231), Expect = 1e-18
Identities = 44/92 (47%), Positives = 63/92 (68%), Gaps = 1/92 (1%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MIEAI+ G ++MR+G+HTG VLCG++G R+++FDVWS+DVT AN MES G GR
Sbjct: 355 MIEAIRFVREATGFNVDMRIGIHTGNVLCGVLGLRKWQFDVWSDDVTLANHMESGGVAGR 414
Query: 433 VHISEETSQFLGGSYILEEGEEVFGHKTYFIE 464
VHI++ T +LG + +E G G ++Y +
Sbjct: 415 VHITKATLDYLGDRFEVEPGGGA-GRESYLAD 445
Score = 65.7 bits (153), Expect = 4e-09
Identities = 24/72 (33%), Positives = 50/72 (69%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+++ A+ + +RE + +R+G++ G V+ G++G ++ ++D+WSN V A++M+S G G
Sbjct: 1180 ALMTALDQINRESFQRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVASRMDSCGVMG 1239
Query: 432 RVHISEETSQFL 443
R+ +SE T++ L
Sbjct: 1240 RIQVSENTAKVL 1251
Score = 36.7 bits (81), Expect = 2.1
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 11/91 (12%)
Query: 286 RRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSL 345
R +LE E++ +E+++ SV+P +A+ + + + +T G ++
Sbjct: 219 RVRLECEREQQEQLLLSVIPAYIAAEVKRSIMLKMADACQT-----------AGGQSQTR 267
Query: 346 FRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
F ++ +NVSIL+ADIV FT +S + A
Sbjct: 268 FHEMHVQRHNNVSILYADIVNFTPLSEQLTA 298
>UniRef50_Q8NFM4 Cluster: Adenylate cyclase type 4; n=73;
Euteleostomi|Rep: Adenylate cyclase type 4 - Homo
sapiens (Human)
Length = 1077
Score = 97.1 bits (231), Expect = 1e-18
Identities = 45/101 (44%), Positives = 66/101 (65%), Gaps = 2/101 (1%)
Query: 353 CMDNVSILFAD-IVGFTRMS-SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFK 410
C+ + + D + RM M AI++ G INMRVGVH+G+VLCG++G ++++
Sbjct: 326 CVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATGVDINMRVGVHSGSVLCGVIGLQKWQ 385
Query: 411 FDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYILEE 451
+DVWS+DVT AN ME+ G PGRVHI+ T L G+Y +E+
Sbjct: 386 YDVWSHDVTLANHMEAGGVPGRVHITGATLALLAGAYAVED 426
Score = 58.4 bits (135), Expect = 6e-07
Identities = 28/94 (29%), Positives = 52/94 (55%), Gaps = 5/94 (5%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYIL 449
+RVG++ G V+ G++G ++ ++D+W N V A++MES+G G++ ++EET+ L
Sbjct: 983 LRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSL--- 1039
Query: 450 EEGEEVFGHKTYFIEGRQVFCPYDREQCLTPSNP 483
G + ++G+ C Y LT + P
Sbjct: 1040 --GYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGP 1071
Score = 49.2 bits (112), Expect = 4e-04
Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 12/121 (9%)
Query: 252 LLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASN 311
+L LC ++ GV+ + +R TF + SL RR+L+ EK+ +E ++ S++P LA
Sbjct: 179 VLFLCGNVAGVYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLARE 238
Query: 312 LMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMS 371
+ E + + N+ F + VS+L+ADIVGFTR++
Sbjct: 239 MKAEIMARLQAGQGSRPESTNN------------FHSLYVKRHQGVSVLYADIVGFTRLA 286
Query: 372 S 372
S
Sbjct: 287 S 287
>UniRef50_Q4SUW5 Cluster: Chromosome undetermined SCAF13838, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF13838, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1085
Score = 96.7 bits (230), Expect = 2e-18
Identities = 45/97 (46%), Positives = 65/97 (67%), Gaps = 4/97 (4%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+ I +NMRVG+HTG VLCG++G R++++DVWSNDVT AN ME+ G PG+
Sbjct: 247 MIDTIASVVEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGK 306
Query: 433 VHISEETSQFLGGSYILEEGEEVFGHKTY-FIEGRQV 468
VHI+ T + L G Y +E G FGH+ + F++ ++
Sbjct: 307 VHITRTTLECLNGDYEVEPG---FGHERHAFLQKHRI 340
Score = 54.0 bits (124), Expect = 1e-05
Identities = 18/44 (40%), Positives = 33/44 (75%)
Query: 393 GVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHIS 436
G++ G V+ G++G RR ++D+W N V A++M+S+G PG++ +S
Sbjct: 948 GINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVPGKIQVS 991
Score = 39.5 bits (88), Expect = 0.30
Identities = 31/120 (25%), Positives = 56/120 (46%), Gaps = 22/120 (18%)
Query: 257 VHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQ 316
V++ GV + ++T R F++ + R +LE E + +E+++ S++P +A + +
Sbjct: 93 VNLSGVFVRILTERTQRKVFLQARSCIEERLRLEDENEKQERLLMSLLPRNVAMEMKEDF 152
Query: 317 VTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
+ + +F + DNVSILFADIVGFT ++S A
Sbjct: 153 LKPPER----------------------IFHKIYIQRHDNVSILFADIVGFTSLASQCTA 190
>UniRef50_UPI0000E47CE1 Cluster: PREDICTED: similar to Adenylate
cyclase 2; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Adenylate cyclase 2 -
Strongylocentrotus purpuratus
Length = 889
Score = 95.9 bits (228), Expect = 3e-18
Identities = 44/81 (54%), Positives = 57/81 (70%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M EAI+ +NMRVGVHTG VLCG++G R++++DVWS+DVT AN MES G PG
Sbjct: 172 AMCEAIKTVRDATSVDVNMRVGVHTGNVLCGVLGLRKWQYDVWSHDVTLANHMESCGVPG 231
Query: 432 RVHISEETSQFLGGSYILEEG 452
RVHI++ T LG Y +E G
Sbjct: 232 RVHITQATLDNLGLKYEVEPG 252
Score = 59.7 bits (138), Expect = 3e-07
Identities = 19/69 (27%), Positives = 46/69 (66%)
Query: 375 EAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVH 434
+ +++ +++ +R+G++ G V+ G++G R+ ++D+W N V A++M+++G G +
Sbjct: 777 DKLEQLNKQAFNDFKLRIGINHGPVVAGVIGARKPQYDIWGNTVNVASRMDTTGMIGEIQ 836
Query: 435 ISEETSQFL 443
++EET+ L
Sbjct: 837 VTEETANVL 845
Score = 54.4 bits (125), Expect = 1e-05
Identities = 41/119 (34%), Positives = 63/119 (52%), Gaps = 10/119 (8%)
Query: 255 LCVHIIGV-HIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLM 313
+CV+ IGV H +L+ V R TF+ + R +LE E+ +E+++ SV+P LA +
Sbjct: 3 VCVNFIGVCHKHLLD-VAQRRTFLDTRSCIESRIKLEHEQAQQERLLLSVLPAHLAYEMK 61
Query: 314 NEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSS 372
E + +P S IS+ S + F + NVSIL+ADIVGFT ++S
Sbjct: 62 TEMMARV-------RDPTMSPISHRPSS-STHFHSLYVKRHKNVSILYADIVGFTALAS 112
>UniRef50_UPI0000DB73AC Cluster: PREDICTED: similar to Adenylyl
cyclase 76E CG7978-PA; n=1; Apis mellifera|Rep:
PREDICTED: similar to Adenylyl cyclase 76E CG7978-PA -
Apis mellifera
Length = 969
Score = 95.9 bits (228), Expect = 3e-18
Identities = 42/80 (52%), Positives = 58/80 (72%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI+ G ++MR+G+HTG VLCG++G R+++FDVWS+DVT AN MES G PGR
Sbjct: 346 MIDAIKFVREATGFNVDMRIGIHTGNVLCGVLGLRKWQFDVWSDDVTLANHMESGGLPGR 405
Query: 433 VHISEETSQFLGGSYILEEG 452
VHI++ T LG + +E G
Sbjct: 406 VHITKATLLQLGNRFEVEPG 425
Score = 62.1 bits (144), Expect = 5e-08
Identities = 25/101 (24%), Positives = 60/101 (59%), Gaps = 5/101 (4%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+++ + + ++E + +R+G++ G V+ G+VG ++ ++D+W N V A++M+S G+ G
Sbjct: 861 ALMTILDQINKESFQKFKLRIGLNHGPVIAGVVGAQKPQYDIWGNTVNVASRMDSCGEMG 920
Query: 432 RVHISEETSQFLGGSYILEEGEEVFGHKTYFIEGRQVFCPY 472
+V ++E+T++ L + G E+ +++G+ Y
Sbjct: 921 KVQVTEDTAKIL-----IAAGYELICRGPTYVKGKGTLITY 956
>UniRef50_UPI000069E67B Cluster: Adenylate cyclase type 1 (EC
4.6.1.1) (Adenylate cyclase type I) (ATP
pyrophosphate-lyase 1) (Adenylyl cyclase 1)
(Ca(2+)/calmodulin- activated adenylyl cyclase).; n=1;
Xenopus tropicalis|Rep: Adenylate cyclase type 1 (EC
4.6.1.1) (Adenylate cyclase type I) (ATP
pyrophosphate-lyase 1) (Adenylyl cyclase 1)
(Ca(2+)/calmodulin- activated adenylyl cyclase). -
Xenopus tropicalis
Length = 781
Score = 95.9 bits (228), Expect = 3e-18
Identities = 43/87 (49%), Positives = 60/87 (68%), Gaps = 3/87 (3%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+ I +NMRVG+HTG VLCG++G R++++DVWSNDVT AN ME+ G PG+
Sbjct: 76 MIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGK 135
Query: 433 VHISEETSQFLGGSYILEEGEEVFGHK 459
VHI++ T + L G Y +E G +GH+
Sbjct: 136 VHITKNTLECLNGDYEVEPG---YGHE 159
Score = 62.5 bits (145), Expect = 4e-08
Identities = 29/100 (29%), Positives = 56/100 (56%), Gaps = 6/100 (6%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M + + E + + +RVG++ G V+ G++G RR ++D+W N V A++M+S+G G+
Sbjct: 678 MFDVLDEINYQSYNEFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGK 737
Query: 433 VHISEETSQFLGG---SYILEEGEEVFGH---KTYFIEGR 466
+ ++E+ + L ++ V G TYF+EG+
Sbjct: 738 IQVTEDVHRILKSCNYEFVCRGKVSVKGKGEMLTYFLEGK 777
>UniRef50_UPI000069E679 Cluster: Adenylate cyclase type 1 (EC
4.6.1.1) (Adenylate cyclase type I) (ATP
pyrophosphate-lyase 1) (Adenylyl cyclase 1)
(Ca(2+)/calmodulin- activated adenylyl cyclase).; n=2;
Xenopus tropicalis|Rep: Adenylate cyclase type 1 (EC
4.6.1.1) (Adenylate cyclase type I) (ATP
pyrophosphate-lyase 1) (Adenylyl cyclase 1)
(Ca(2+)/calmodulin- activated adenylyl cyclase). -
Xenopus tropicalis
Length = 953
Score = 95.9 bits (228), Expect = 3e-18
Identities = 43/87 (49%), Positives = 60/87 (68%), Gaps = 3/87 (3%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+ I +NMRVG+HTG VLCG++G R++++DVWSNDVT AN ME+ G PG+
Sbjct: 226 MIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGK 285
Query: 433 VHISEETSQFLGGSYILEEGEEVFGHK 459
VHI++ T + L G Y +E G +GH+
Sbjct: 286 VHITKNTLECLNGDYEVEPG---YGHE 309
Score = 62.5 bits (145), Expect = 4e-08
Identities = 29/100 (29%), Positives = 56/100 (56%), Gaps = 6/100 (6%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M + + E + + +RVG++ G V+ G++G RR ++D+W N V A++M+S+G G+
Sbjct: 850 MFDVLDEINYQSYNEFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGK 909
Query: 433 VHISEETSQFLGG---SYILEEGEEVFGH---KTYFIEGR 466
+ ++E+ + L ++ V G TYF+EG+
Sbjct: 910 IQVTEDVHRILKSCNYEFVCRGKVSVKGKGEMLTYFLEGK 949
Score = 42.7 bits (96), Expect = 0.032
Identities = 38/164 (23%), Positives = 77/164 (46%), Gaps = 30/164 (18%)
Query: 219 ILGIIYSIVFEVLNIVLHLS------EQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRM 272
+L I++ + V +I++ + ++ W+ + V +L + V++ GV + ++T
Sbjct: 30 LLAIVFGFMVSVSHIIVTATSISPKKKRLWRT--LVVNAILFVSVNLSGVFVRILTERAQ 87
Query: 273 RGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLN 332
R F++ + R +LE E + +E+++ S++P +A + + + +
Sbjct: 88 RKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPER---------- 137
Query: 333 SRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
+F + DNVSILFADIVGFT ++S A
Sbjct: 138 ------------IFHKIYIQRHDNVSILFADIVGFTSLASQCTA 169
>UniRef50_UPI000065D458 Cluster: Adenylate cyclase type 3 (EC
4.6.1.1) (Adenylate cyclase type III) (ATP
pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III)
(AC3) (Adenylate cyclase, olfactive type).; n=1;
Takifugu rubripes|Rep: Adenylate cyclase type 3 (EC
4.6.1.1) (Adenylate cyclase type III) (ATP
pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III)
(AC3) (Adenylate cyclase, olfactive type). - Takifugu
rubripes
Length = 1159
Score = 95.9 bits (228), Expect = 3e-18
Identities = 44/81 (54%), Positives = 58/81 (71%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M++AI + ++MRVGVHTGTVL G++G +R++FDVWS DVT ANKMES G PG
Sbjct: 420 AMVDAISYVREKTKTEVDMRVGVHTGTVLGGVLGQKRWQFDVWSTDVTVANKMESGGIPG 479
Query: 432 RVHISEETSQFLGGSYILEEG 452
+VHIS+ T L G + LE G
Sbjct: 480 KVHISQTTKDSLHGEFELEPG 500
Score = 56.0 bits (129), Expect = 3e-06
Identities = 22/72 (30%), Positives = 41/72 (56%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SM + +++ +R+G++ G VL G++G R+ +D+W N V A++MES+G G
Sbjct: 1039 SMKVTLNNLNKQSFNNFMLRIGINKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMG 1098
Query: 432 RVHISEETSQFL 443
+ + E+ L
Sbjct: 1099 NIQVVEDCYNIL 1110
Score = 54.8 bits (126), Expect = 8e-06
Identities = 46/165 (27%), Positives = 79/165 (47%), Gaps = 22/165 (13%)
Query: 230 VLNIVLHLSEQEWQASGMFVR-----ILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLL 284
VL +++ S ++ M VR ++L LC +GV Y M + R F++ +SL
Sbjct: 191 VLGVIVTRSFEDNLQGPMLVRQLLASVMLYLCAATMGVMSYYMADRKYRMAFLEARRSLE 250
Query: 285 VRRQLEMEKQLKEKMIHSVMPPKLASNL---MNEQVTEADTNVKTYHNPL---------- 331
V+ LE + +E+++ S++P +A + M +Q + D + N +
Sbjct: 251 VKVTLEEQSTQQEELLLSILPKHIADEMLQGMKDQAQQQDVQQQQQFNTMYMYRHENVRS 310
Query: 332 NSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
S + S + + +P+ C SILFADIVGFT++SS A
Sbjct: 311 ESLFHHRDSLVSAKRQPYCFCC----SILFADIVGFTQLSSACSA 351
>UniRef50_Q9VV68 Cluster: CG32158-PB, isoform B; n=12;
Coelomata|Rep: CG32158-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 1662
Score = 95.9 bits (228), Expect = 3e-18
Identities = 44/81 (54%), Positives = 57/81 (70%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI +NMRVG+HTG V CG++G +++FDVWSNDVT AN MES G PGR
Sbjct: 616 MIDAIALVREVMAVNVNMRVGIHTGRVHCGVLGLVKWQFDVWSNDVTLANHMESGGIPGR 675
Query: 433 VHISEETSQFLGGSYILEEGE 453
VHI++ET + L G Y +E G+
Sbjct: 676 VHITKETLKCLDGDYEVEVGK 696
Score = 58.4 bits (135), Expect = 6e-07
Identities = 31/117 (26%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
+ + I+E + MR+G++ G V+ G++G + ++D+W N V A++M+S+G
Sbjct: 1189 LFDKIEEVNMHSFNNFRMRIGINIGPVVAGVIGACKPQYDIWGNAVNVASRMDSTGLVDH 1248
Query: 433 VHISEETSQFLGG---SYILEEGEEVFGHK---TYFIEGRQVFCPYDREQCLTPSNP 483
+ +++E Q L G +V G TYF++GR+ + E T P
Sbjct: 1249 IQVTQEMQQILEGRGFELTCRGSVDVKGKGSMITYFLKGRRPIDAKELELAKTEVEP 1305
>UniRef50_O16880 Cluster: Adenylyl cyclase protein 2; n=2;
Caenorhabditis|Rep: Adenylyl cyclase protein 2 -
Caenorhabditis elegans
Length = 1080
Score = 95.9 bits (228), Expect = 3e-18
Identities = 41/77 (53%), Positives = 56/77 (72%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI I++ G +NMR+GVHTG+VLCGI+G R+++FD+WS+DVT AN MES+G PG
Sbjct: 389 MINTIKQVRIATGVDVNMRIGVHTGSVLCGIMGLRKWQFDIWSDDVTLANHMESAGVPGA 448
Query: 433 VHISEETSQFLGGSYIL 449
VHI++ T L G Y +
Sbjct: 449 VHITKSTKDMLLGDYCI 465
Score = 56.8 bits (131), Expect = 2e-06
Identities = 20/84 (23%), Positives = 50/84 (59%), Gaps = 2/84 (2%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M + + +R+ + +R+G+ G ++ G++G ++ ++D+W N V A++M++ G+P
Sbjct: 955 AMSQILDALNRDSFQNFELRIGMSVGPLVAGVIGAQKPQYDIWGNTVNLASRMDTHGEPR 1014
Query: 432 RVHISEETSQFL--GGSYILEEGE 453
++H + + + L GG + G+
Sbjct: 1015 KIHATTDMGRVLQTGGYRVQSRGK 1038
Score = 48.4 bits (110), Expect = 7e-04
Identities = 30/99 (30%), Positives = 54/99 (54%), Gaps = 4/99 (4%)
Query: 278 KVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISN 337
K+ +++ R +LE K +E+++ SV+P LA + ++ + ++ + T P R
Sbjct: 238 KLTEAVYRRTELETLKDRQEQLLLSVIPAYLADQV-SKSIIQSSSTGSTVEVP---RTGK 293
Query: 338 PGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
+ LF ++ DNVSILFADIV FT +++ + A
Sbjct: 294 NNTKNHKLFHDLHVQVHDNVSILFADIVNFTVLAAQLTA 332
>UniRef50_Q7QDV4 Cluster: ENSANGP00000010056; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000010056 - Anopheles gambiae
str. PEST
Length = 881
Score = 95.5 bits (227), Expect = 4e-18
Identities = 41/80 (51%), Positives = 58/80 (72%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI+ G ++MR+G+HTG VLCG++G R+++FDVWS+DVT AN MES G GR
Sbjct: 209 MIDAIRFVREATGFNVDMRIGIHTGNVLCGVLGLRKWQFDVWSDDVTLANHMESGGVAGR 268
Query: 433 VHISEETSQFLGGSYILEEG 452
VHI++ T +LG + +E G
Sbjct: 269 VHITKATLDYLGDMFEVEPG 288
Score = 64.9 bits (151), Expect = 7e-09
Identities = 24/72 (33%), Positives = 50/72 (69%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+++ A+ + +RE + +R+G++ G V+ G++G ++ ++D+WSN V A++M+S G G
Sbjct: 783 ALMTALDQINRESFQRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVASRMDSCGVMG 842
Query: 432 RVHISEETSQFL 443
RV ++E T++ L
Sbjct: 843 RVQVTENTAKVL 854
>UniRef50_UPI00015B5F6F Cluster: PREDICTED: similar to
ENSANGP00000010056; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010056 - Nasonia
vitripennis
Length = 947
Score = 95.1 bits (226), Expect = 6e-18
Identities = 41/80 (51%), Positives = 58/80 (72%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MIEAI+ G ++MR+G+HTG VLCG++G R+++FDVWS+DVT AN MES G PG+
Sbjct: 274 MIEAIRFVREATGFNVDMRIGIHTGNVLCGVLGLRKWQFDVWSDDVTLANHMESGGLPGK 333
Query: 433 VHISEETSQFLGGSYILEEG 452
VH+++ T LG + +E G
Sbjct: 334 VHVTKATLLQLGDRFEVEPG 353
Score = 62.9 bits (146), Expect = 3e-08
Identities = 22/72 (30%), Positives = 49/72 (68%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
S+ + + +RE + +R+G++ G V+ G+VG ++ ++D+W N V A++M+S G+ G
Sbjct: 839 SLTTLLDQINRESFQRFKLRIGLNHGPVIAGVVGAQKPQYDIWGNTVNVASRMDSCGEMG 898
Query: 432 RVHISEETSQFL 443
++ ++E+T++ L
Sbjct: 899 KIQVTEDTAKIL 910
>UniRef50_Q9Y1V0 Cluster: Adenylyl cyclase 78C-L; n=4;
Sophophora|Rep: Adenylyl cyclase 78C-L - Drosophila
melanogaster (Fruit fly)
Length = 1718
Score = 95.1 bits (226), Expect = 6e-18
Identities = 41/80 (51%), Positives = 58/80 (72%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI++ +NMR+G+H+G+V+CG++G +++ FDVWSNDV AN MES G PGR
Sbjct: 654 MIKAIKDVRLHTHVDLNMRIGIHSGSVMCGVLGNKKWHFDVWSNDVIIANHMESGGIPGR 713
Query: 433 VHISEETSQFLGGSYILEEG 452
VHISE T + L +Y +E G
Sbjct: 714 VHISEATLKCLNDAYEVEPG 733
Score = 58.4 bits (135), Expect = 6e-07
Identities = 25/81 (30%), Positives = 50/81 (61%), Gaps = 2/81 (2%)
Query: 363 DIVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFAN 422
D+V F +M + ++E + + +RVG+ +G ++ G++G R+ +D+W N V A+
Sbjct: 1470 DLVEFA--FAMKQKLEEINGDAFNNFQLRVGICSGPLVSGVIGARKPVYDIWGNTVNVAS 1527
Query: 423 KMESSGKPGRVHISEETSQFL 443
+M+S+G+ RV + E T++ L
Sbjct: 1528 RMDSTGENWRVQVPENTAELL 1548
Score = 49.6 bits (113), Expect = 3e-04
Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 18/132 (13%)
Query: 247 MFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPP 306
+F +L +++ G++ +T R F++ +++ +++ E E Q +K++ S++P
Sbjct: 482 IFANFILYTAINVAGMYTKYLTDRGQRLAFIETHKAMEHKKESEKELQRTQKLLDSILPN 541
Query: 307 KLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVG 366
+ + + +E D V+T N L + MDNVSILFADI G
Sbjct: 542 IVNNQIRSEMYKGTDPTVETQFNKLY------------------VYPMDNVSILFADIKG 583
Query: 367 FTRMSSMIEAIQ 378
FT ++S A Q
Sbjct: 584 FTELASKTSAQQ 595
>UniRef50_P40145 Cluster: Adenylate cyclase type 8 (EC 4.6.1.1)
(Adenylate cyclase type VIII) (ATP pyrophosphate-lyase
8) (Adenylyl cyclase 8) (Ca(2+)/calmodulin- activated
adenylyl cyclase); n=29; Euteleostomi|Rep: Adenylate
cyclase type 8 (EC 4.6.1.1) (Adenylate cyclase type
VIII) (ATP pyrophosphate-lyase 8) (Adenylyl cyclase 8)
(Ca(2+)/calmodulin- activated adenylyl cyclase) - Homo
sapiens (Human)
Length = 1251
Score = 95.1 bits (226), Expect = 6e-18
Identities = 41/81 (50%), Positives = 58/81 (71%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SMI+ I+ ++MR+G+H+G+VLCG++G R+++FDVWS DV ANK+ES G PG
Sbjct: 488 SMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPG 547
Query: 432 RVHISEETSQFLGGSYILEEG 452
R+HIS+ T L G Y +EEG
Sbjct: 548 RIHISKATLDCLNGDYNVEEG 568
Score = 65.7 bits (153), Expect = 4e-09
Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 10/105 (9%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
++ E+IQE ++ +R+G+ G+V+ G++G ++ ++D+W V A++M+S+G G
Sbjct: 1069 ALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSG 1128
Query: 432 RVHISEETSQFL----------GGSYILEEGEEVFGHKTYFIEGR 466
R+ + EET L G Y+ E+ KTYF+ GR
Sbjct: 1129 RIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGR 1173
Score = 50.4 bits (115), Expect = 2e-04
Identities = 38/135 (28%), Positives = 68/135 (50%), Gaps = 19/135 (14%)
Query: 252 LLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASN 311
+L +C++ G+ I ++ R F++ + + R +LE E Q +E+++ SV+P +
Sbjct: 326 VLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLE 385
Query: 312 LMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMS 371
++N+ TNV+ H ++ F + +NVSILFAD+ GFT +S
Sbjct: 386 MINDM-----TNVEDEH-------------LQHQFHRIYIHRYENVSILFADVKGFTNLS 427
Query: 372 SMIEAIQEFDRERGE 386
+ + A QE R E
Sbjct: 428 TTLSA-QELVRMLNE 441
>UniRef50_UPI0000DB7A4D Cluster: PREDICTED: similar to Adenylyl
cyclase 78C CG10564-PA; n=2; Apocrita|Rep: PREDICTED:
similar to Adenylyl cyclase 78C CG10564-PA - Apis
mellifera
Length = 1299
Score = 94.7 bits (225), Expect = 8e-18
Identities = 42/80 (52%), Positives = 58/80 (72%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI++ +NMR+G+H+G+VLCG++G R+++FDVWS DVT AN +ES G PGR
Sbjct: 459 MIKAIRDVRYTTKVDLNMRIGIHSGSVLCGVLGLRKWQFDVWSYDVTLANHLESGGIPGR 518
Query: 433 VHISEETSQFLGGSYILEEG 452
VHISE+T L Y +E G
Sbjct: 519 VHISEDTLNCLNDVYEVEPG 538
Score = 55.2 bits (127), Expect = 6e-06
Identities = 28/84 (33%), Positives = 52/84 (61%), Gaps = 6/84 (7%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL--GGS 446
++RVG+ G ++ G++G R+ FD+W N V A++M+S+G G++ + ++ ++FL G
Sbjct: 1177 DLRVGISCGPLVGGVIGARKPVFDIWGNTVNLASRMDSTGVMGKIQVPQDIARFLESRGY 1236
Query: 447 YILEEG-EEVFGH---KTYFIEGR 466
+ G EV G +TYF+ G+
Sbjct: 1237 QTQKRGLIEVKGKGTMETYFVLGK 1260
Score = 46.8 bits (106), Expect = 0.002
Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 13/126 (10%)
Query: 251 ILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLAS 310
+LL L +++ G++ +T R F++ +S+ R++ + E +EK++ SV+P +A
Sbjct: 290 VLLYLAMNLAGMYTKYLTDRGQRQAFLETHRSMETRQRTQNENNRQEKLLLSVLPDFVAK 349
Query: 311 NLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRM 370
++ + E P + F + +NVSILFADI GFT +
Sbjct: 350 EMIRDIARETARGGTISFTP-------------NQFHRIYIHRYENVSILFADIKGFTAL 396
Query: 371 SSMIEA 376
+S A
Sbjct: 397 ASQCSA 402
>UniRef50_UPI0000D56083 Cluster: PREDICTED: similar to CG10564-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG10564-PA - Tribolium castaneum
Length = 1551
Score = 94.7 bits (225), Expect = 8e-18
Identities = 42/80 (52%), Positives = 60/80 (75%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI++ + +NMR+G+H+G+VLCG++G R+++FD++S DV AN MES G PGR
Sbjct: 466 MIKAIRDTRTKTQVDLNMRIGIHSGSVLCGVLGLRKWQFDIFSYDVRLANHMESGGIPGR 525
Query: 433 VHISEETSQFLGGSYILEEG 452
VHISE T Q L G+Y +E G
Sbjct: 526 VHISEATYQCLNGAYEVEPG 545
Score = 72.5 bits (170), Expect = 4e-11
Identities = 37/102 (36%), Positives = 63/102 (61%), Gaps = 6/102 (5%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M + + E ++E +RVGV G+++CG++G R+ FD+W N V A++M+S+G G
Sbjct: 1208 AMRQKLDEINKESFNNFGLRVGVSCGSLVCGVIGARKPVFDIWGNTVNEASRMDSTGVIG 1267
Query: 432 RVHISEETSQFLG--GSYILEEG-EEVFGH---KTYFIEGRQ 467
++ + + T+Q LG G + + G EV G +TYF+ GRQ
Sbjct: 1268 QIQVPKYTAQLLGVRGYEVKKRGIIEVKGKGQMETYFVMGRQ 1309
Score = 45.2 bits (102), Expect = 0.006
Identities = 40/148 (27%), Positives = 66/148 (44%), Gaps = 18/148 (12%)
Query: 235 LHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQ 294
LH + E + + LL + V+ G++ +T R F++ +S+ R + + E
Sbjct: 285 LH-DDNECKIRRIVANFLLYVAVNFAGMYTKYLTDRSQRKAFLETHRSMETRYRTQSEND 343
Query: 295 LKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCM 354
+EK++ SV+P +A ++ + E V H F +
Sbjct: 344 KQEKLLLSVLPDFVAKEMIRDIEREERGGVFQPHQ----------------FHKIYIHRY 387
Query: 355 DNVSILFADIVGFTRMSSMIEAIQEFDR 382
+NVSILFADI GFT ++S A QE R
Sbjct: 388 ENVSILFADIKGFTALASQCSA-QELVR 414
>UniRef50_Q08828 Cluster: Adenylate cyclase type 1 (EC 4.6.1.1)
(Adenylate cyclase type I) (ATP pyrophosphate-lyase 1)
(Adenylyl cyclase 1) (Ca(2+)/calmodulin- activated
adenylyl cyclase); n=27; Euteleostomi|Rep: Adenylate
cyclase type 1 (EC 4.6.1.1) (Adenylate cyclase type I)
(ATP pyrophosphate-lyase 1) (Adenylyl cyclase 1)
(Ca(2+)/calmodulin- activated adenylyl cyclase) - Homo
sapiens (Human)
Length = 1119
Score = 94.7 bits (225), Expect = 8e-18
Identities = 43/87 (49%), Positives = 60/87 (68%), Gaps = 3/87 (3%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+ I +NMRVG+HTG VLCG++G R++++DVWSNDVT AN ME++G PG+
Sbjct: 378 MIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGK 437
Query: 433 VHISEETSQFLGGSYILEEGEEVFGHK 459
VHI++ T L G Y +E G +GH+
Sbjct: 438 VHITKTTLACLNGDYEVEPG---YGHE 461
Score = 65.3 bits (152), Expect = 5e-09
Identities = 32/100 (32%), Positives = 56/100 (56%), Gaps = 6/100 (6%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M + + E + + +RVG++ G V+ G++G RR ++D+W N V A++M+S+G GR
Sbjct: 958 MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR 1017
Query: 433 VHISEETSQFLGG---SYILEEGEEVFGH---KTYFIEGR 466
+ ++EE + L ++ V G TYF+EGR
Sbjct: 1018 IQVTEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGR 1057
Score = 40.7 bits (91), Expect = 0.13
Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 24/135 (17%)
Query: 242 WQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIH 301
W+ G LL + V++ GV + ++T R F++ + R +LE E + +E+++
Sbjct: 211 WRTLG--ANALLFVGVNMYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLM 268
Query: 302 SVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILF 361
S++P +A + + + + +F + DNVSILF
Sbjct: 269 SLLPRNVAMEMKEDFLKPPER----------------------IFHKIYIQRHDNVSILF 306
Query: 362 ADIVGFTRMSSMIEA 376
ADIVGFT ++S A
Sbjct: 307 ADIVGFTGLASQCTA 321
>UniRef50_Q4S9A3 Cluster: Chromosome undetermined SCAF14699, whole
genome shotgun sequence; n=3; Euteleostomi|Rep:
Chromosome undetermined SCAF14699, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1292
Score = 93.9 bits (223), Expect = 1e-17
Identities = 42/81 (51%), Positives = 59/81 (72%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M+EAI + ++MRVGVH+GTVL G++G +R+++DVWS DVT ANKME+ G PG
Sbjct: 426 AMVEAISYVREKTQTDVDMRVGVHSGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPG 485
Query: 432 RVHISEETSQFLGGSYILEEG 452
RVHIS+ T + L G + +E G
Sbjct: 486 RVHISQSTLECLHGEFDVEPG 506
Score = 57.6 bits (133), Expect = 1e-06
Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 6/136 (4%)
Query: 247 MFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPP 306
+ +++ C +G+ Y M + R F++ QSL V+ LE + Q +E+++ S++P
Sbjct: 226 LLANVVIYACAITVGIMSYYMADRKHRKAFLEARQSLEVKLNLEEQSQQQERLLLSILPK 285
Query: 307 KLASNLMNEQVTEADTNVKTYHNPL------NSRISNPGSDIKSLFRPFNMSCMDNVSIL 360
+A ++ + E N + N R ++ + + VSIL
Sbjct: 286 HIADEMLQDMKKEPSQKEMQQFNTMYMYRHENVRYTHRAYADPHVRATERLCACGLVSIL 345
Query: 361 FADIVGFTRMSSMIEA 376
FADIVGFT++SS A
Sbjct: 346 FADIVGFTQLSSSCSA 361
Score = 50.8 bits (116), Expect = 1e-04
Identities = 18/46 (39%), Positives = 32/46 (69%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHI 435
+R+G++ G VL G++G R+ +D+W N V A++MES+G G + +
Sbjct: 1157 LRIGLNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQV 1202
>UniRef50_Q0C7B2 Cluster: Adenylate cyclase; n=2; Culicidae|Rep:
Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
Length = 1400
Score = 93.9 bits (223), Expect = 1e-17
Identities = 40/80 (50%), Positives = 58/80 (72%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI++ + ++MR+G+H+G+V+CG++G +++ FDVWSNDV AN MES G PGR
Sbjct: 448 MIKAIKDVRVQTNVDLDMRIGIHSGSVMCGVLGEKKWHFDVWSNDVIIANHMESGGVPGR 507
Query: 433 VHISEETSQFLGGSYILEEG 452
VHISE T L +Y +E G
Sbjct: 508 VHISEATLNCLNDTYEVEPG 527
Score = 57.6 bits (133), Expect = 1e-06
Identities = 45/184 (24%), Positives = 88/184 (47%), Gaps = 11/184 (5%)
Query: 307 KLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIK--SLFRPFNMSCMDNVSI-LFAD 363
K ++NE +++ D+ ++ +I G+ S R N + +D D
Sbjct: 1092 KACIRILNEIISDFDSLLEEERFKTVEKIKTVGATYMAASNLRSGNKTKVDEKDEEAVCD 1151
Query: 364 IVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANK 423
+V F +M + +QE +++ +RVG+ +G ++ G++G R+ +D+W N V A++
Sbjct: 1152 LVEFAL--AMRQKLQEVNKDAFNTFQLRVGISSGPLVSGVIGARKPVYDIWGNTVNVASR 1209
Query: 424 MESSGKPGRVHISEETSQFL--GGSYILEEGE-EVFGH---KTYFIEGRQVFCPYDREQC 477
M+S+G+ +V + + T+ L G ++ GE V G TY++ G V
Sbjct: 1210 MDSTGENWKVQVPDYTAALLQTKGYTCVQRGEVNVKGKGLMLTYWVLGMNVSASQLTSPA 1269
Query: 478 LTPS 481
L P+
Sbjct: 1270 LMPA 1273
Score = 55.2 bits (127), Expect = 6e-06
Identities = 45/165 (27%), Positives = 79/165 (47%), Gaps = 20/165 (12%)
Query: 217 CVILGIIYSI---VFEVLNIVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMR 273
C+I G + +I + +N LH S+ M LL L ++ G++ +T R
Sbjct: 242 CMIAGSVSAICHLIVTTINKFLHESDTTCIVRQMIANSLLYLAINFAGMYTKYLTDRGQR 301
Query: 274 GTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNS 333
F++ +++ +R+ E E Q ++++ S++P + +++ E Y +P
Sbjct: 302 LAFIETHKAMEHKRESEKEYQRTQRLLDSILPMFVNNDIRKEM----------YKSP--- 348
Query: 334 RISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEAIQ 378
P D + F+ + MDNVSILFADI GFT ++S A Q
Sbjct: 349 --EQPQVDTQ--FKKLYIYHMDNVSILFADIKGFTELASKTSAQQ 389
>UniRef50_UPI00015A6AA9 Cluster: Adenylate cyclase type 8 (EC
4.6.1.1) (Adenylate cyclase type VIII) (ATP
pyrophosphate-lyase 8) (Adenylyl cyclase 8)
(Ca(2+)/calmodulin- activated adenylyl cyclase).; n=1;
Danio rerio|Rep: Adenylate cyclase type 8 (EC 4.6.1.1)
(Adenylate cyclase type VIII) (ATP pyrophosphate-lyase
8) (Adenylyl cyclase 8) (Ca(2+)/calmodulin- activated
adenylyl cyclase). - Danio rerio
Length = 888
Score = 93.5 bits (222), Expect = 2e-17
Identities = 41/81 (50%), Positives = 57/81 (70%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SMI+ I+ I+MR+G+H+G+VLCG++G R+++FDVWS DV ANK+ES G PG
Sbjct: 168 SMIKTIRYVRSRTKHDIDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPG 227
Query: 432 RVHISEETSQFLGGSYILEEG 452
R+HIS+ L G Y +EEG
Sbjct: 228 RIHISKAALDCLNGDYEVEEG 248
Score = 60.1 bits (139), Expect = 2e-07
Identities = 22/69 (31%), Positives = 44/69 (63%)
Query: 375 EAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVH 434
E+IQE ++ +R+G+ G+V+ G++G ++ ++D+W V A++M+S+G G++
Sbjct: 790 ESIQEINKHSFNNFQLRIGMAHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGKIQ 849
Query: 435 ISEETSQFL 443
+ EET L
Sbjct: 850 LPEETYAIL 858
Score = 52.4 bits (120), Expect = 4e-05
Identities = 39/140 (27%), Positives = 70/140 (50%), Gaps = 19/140 (13%)
Query: 247 MFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPP 306
+ ++LL LC++ G+ I ++ R F++ + + R +LE E Q +E+++ SV+P
Sbjct: 1 LLAQVLLFLCINTAGMFISYLSDRAQRQAFLETRRCIEARLRLETENQRQERLVLSVLPR 60
Query: 307 KLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVG 366
+ ++N+ TNV+ ++ F + +NVSILFAD+ G
Sbjct: 61 FVVLEMINDM-----TNVE-------------DETLQHQFHRIYIHRYENVSILFADVKG 102
Query: 367 FTRMSSMIEAIQEFDRERGE 386
FT +S+ + A QE R E
Sbjct: 103 FTNLSTTLSA-QELVRMLNE 121
>UniRef50_A7S0C5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1212
Score = 93.1 bits (221), Expect = 2e-17
Identities = 42/82 (51%), Positives = 58/82 (70%), Gaps = 1/82 (1%)
Query: 373 MIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
M+E I E+G + +NMRVG+HTG VL G++G R+++F+ WSNDVT AN MES G PG
Sbjct: 438 MVEHIAHVREEKGVKSLNMRVGIHTGMVLAGVLGQRKWQFEAWSNDVTLANHMESGGIPG 497
Query: 432 RVHISEETSQFLGGSYILEEGE 453
RVHISE T + + +E+G+
Sbjct: 498 RVHISEPTLNSIKDYFEVEDGD 519
Score = 52.8 bits (121), Expect = 3e-05
Identities = 23/77 (29%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Query: 363 DIVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFAN 422
DIV F ++ + + ++E +RVG+ G ++ G++G ++ +D+W N V A+
Sbjct: 977 DIVDFAL--TLRDKLDFINQESFNQFVLRVGICQGPIVAGVIGAKKPHYDIWGNTVNVAS 1034
Query: 423 KMESSGKPGRVHISEET 439
+ME++GK G + I+ +T
Sbjct: 1035 RMETTGKAGCIQITAQT 1051
Score = 49.2 bits (112), Expect = 4e-04
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 17/162 (10%)
Query: 217 CVILGIIYSIVFEVLNIVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTF 276
C + I+ SI V+ + + L+ +C +I+G Y + + R +
Sbjct: 240 CAVFAIMISIAHLVVAGTQARMNLNYLGQQLVANTLVFVCANILGAIDYHIADRKQRRSV 299
Query: 277 MKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRIS 336
++ +SL V+ L+ + Q + +++ SV+P +A + + E D N N
Sbjct: 300 LETRESLEVKLTLDAQNQQQRRLLLSVLPKHVAEEMTKD--FEGDGNPALTDNAF----- 352
Query: 337 NPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEAIQ 378
K LF + D SILFADIVGFT +SS A Q
Sbjct: 353 ------KKLF----IRTHDTCSILFADIVGFTELSSKCTAEQ 384
>UniRef50_Q4SNI3 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15
SCAF14542, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 971
Score = 92.7 bits (220), Expect = 3e-17
Identities = 40/81 (49%), Positives = 57/81 (70%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SM++ I+ I+MR+G+H+G+VLCG++G R+++FDVWS DV ANK+ES G PG
Sbjct: 201 SMLKTIRYVRSRTKHDIDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPG 260
Query: 432 RVHISEETSQFLGGSYILEEG 452
R+HIS+ L G Y +EEG
Sbjct: 261 RIHISKAALDCLNGDYEVEEG 281
Score = 49.6 bits (113), Expect = 3e-04
Identities = 17/54 (31%), Positives = 38/54 (70%), Gaps = 1/54 (1%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
+G+++ G+ G+V+ G++G ++ ++D+W V A++M+S+G G++ + EET
Sbjct: 802 DGLSL-AGMAQGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGKIQVPEET 854
Score = 38.3 bits (85), Expect = 0.70
Identities = 33/137 (24%), Positives = 64/137 (46%), Gaps = 3/137 (2%)
Query: 252 LLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEME--KQLKEKMIHSVMPPKLA 309
+L +C++ G+ I ++ R F++ + + R +LE E +Q+++ S +
Sbjct: 19 VLFMCMNTAGIFISYLSDRAQRQAFLETRRCIEARLRLETENQRQVRKGGRGSGDRTLIT 78
Query: 310 SNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTR 369
L+ E++ + +N + ++ F + +NVSILFAD+ GFT
Sbjct: 79 CWLLQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTN 138
Query: 370 MSSMIEAIQEFDRERGE 386
+S+ + A QE R E
Sbjct: 139 LSTTLPA-QELVRMLNE 154
>UniRef50_Q1MU16 Cluster: ORF for hypothetical protein; n=2;
Apocrita|Rep: ORF for hypothetical protein - Apis
mellifera (Honeybee)
Length = 998
Score = 92.7 bits (220), Expect = 3e-17
Identities = 42/79 (53%), Positives = 56/79 (70%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SM+EAI+ + ++MRVG+HTG VL G++G R+++FDV+S DV ANKMESSG G
Sbjct: 347 SMVEAIKYVQQTTNSPVDMRVGIHTGAVLAGVLGQRQWQFDVYSKDVELANKMESSGMAG 406
Query: 432 RVHISEETSQFLGGSYILE 450
RVHIS T FL G + +E
Sbjct: 407 RVHISNATLSFLNGEFEVE 425
Score = 56.4 bits (130), Expect = 2e-06
Identities = 21/69 (30%), Positives = 43/69 (62%)
Query: 375 EAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVH 434
+A+ + + +++G++ G V G++G R+ +D+W N V A++MES+GK G +
Sbjct: 879 KALSSINEQSFNHFVLKMGINHGPVTAGVIGARKPHYDIWGNTVNVASRMESTGKVGCIQ 938
Query: 435 ISEETSQFL 443
+++ET + L
Sbjct: 939 VTDETRKIL 947
Score = 52.0 bits (119), Expect = 5e-05
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 22/160 (13%)
Query: 217 CVILGIIYSIVFEVLNIVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTF 276
CV+L + V+ + + L + + + + + L ++G+ Y +T + R F
Sbjct: 154 CVVLACSTATVYVMSVVGLSKAPAQIPVDVLVLTVTLSASAMVLGLSSYSLTEFQQRRAF 213
Query: 277 MKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRIS 336
++ QSL V+ +E + +E+++ SV+P +A + + DT
Sbjct: 214 LETRQSLEVQLVIEEQSTEQERLLLSVLPEHVAVKMRQDLGASLDTQ------------- 260
Query: 337 NPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSMIEA 376
F+ MS +NVSIL+ADIVGFT +SS A
Sbjct: 261 ---------FKKIYMSRHENVSILYADIVGFTAISSTYSA 291
>UniRef50_UPI000065E155 Cluster: Adenylate cyclase type 8 (EC
4.6.1.1) (Adenylate cyclase type VIII) (ATP
pyrophosphate-lyase 8) (Adenylyl cyclase 8)
(Ca(2+)/calmodulin- activated adenylyl cyclase).; n=4;
Clupeocephala|Rep: Adenylate cyclase type 8 (EC 4.6.1.1)
(Adenylate cyclase type VIII) (ATP pyrophosphate-lyase
8) (Adenylyl cyclase 8) (Ca(2+)/calmodulin- activated
adenylyl cyclase). - Takifugu rubripes
Length = 1020
Score = 92.3 bits (219), Expect = 4e-17
Identities = 42/81 (51%), Positives = 58/81 (71%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SMI AI+ RE ++MR+GVH+G+VLCG++G ++++FD+WS DV AN +E++G PG
Sbjct: 369 SMINAIRYIRREIQLELDMRIGVHSGSVLCGVLGLQKWQFDIWSWDVDIANSLEAAGVPG 428
Query: 432 RVHISEETSQFLGGSYILEEG 452
RVHIS T LGG Y E G
Sbjct: 429 RVHISRATLDCLGGIYETEVG 449
Score = 61.7 bits (143), Expect = 7e-08
Identities = 37/134 (27%), Positives = 65/134 (48%), Gaps = 5/134 (3%)
Query: 312 LMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSL--FRPFNMSCMDNVSILFADIVGFTR 369
L+N +T+ D + + +I GS + P C D L +++V F
Sbjct: 864 LLNHIITDFDELLDESYFQDVEKIKTMGSSYMAASGLSPDRQECEDGWHHL-SELVLFAL 922
Query: 370 MSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
SM E ++ + + G +RVG+ G V+ G++G + ++D+W V A++MES+G
Sbjct: 923 --SMQETLKHINTDTGNSFQLRVGIAHGPVIAGVIGATKPQYDIWGTTVNVASRMESTGV 980
Query: 430 PGRVHISEETSQFL 443
G + + E TS L
Sbjct: 981 SGMIQVPESTSCIL 994
Score = 50.8 bits (116), Expect = 1e-04
Identities = 42/171 (24%), Positives = 83/171 (48%), Gaps = 4/171 (2%)
Query: 218 VILGIIYSIVFEVLNIVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFM 277
++ G I SI+ VL++ H + + + LL L ++ G+ I+ ++ R +F+
Sbjct: 154 IVAGTITSILDLVLDVFSHYGDLAIVRK-VLSKALLYLAMNTAGLSIHYLSDRTQRQSFL 212
Query: 278 KVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISN 337
+ + + R +LE E Q +E+++ S++P L +++ + D + + +
Sbjct: 213 ETRRCIEGRVRLERENQRQERLVMSILPRFLVLDMIGDMAPIDDYLLPQQFHKIYIHHYK 272
Query: 338 PGSDIKSLFRPFNMSCMDNV--SILFADIVGFTRMSSMIEAIQEFDRERGE 386
+ + F F + + SILFADI+GFT +S ++ A QE R E
Sbjct: 273 DVRHLCAFFVMFEIHHRLALFCSILFADIIGFTSLSLILSA-QELVRTLNE 322
>UniRef50_Q9W037 Cluster: CG32301-PA; n=1; Drosophila
melanogaster|Rep: CG32301-PA - Drosophila melanogaster
(Fruit fly)
Length = 1076
Score = 91.1 bits (216), Expect = 9e-17
Identities = 38/82 (46%), Positives = 55/82 (67%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MIE +E + R + I++R+GVH+G +L GI+G +++FD+WS DV N++ESSG PG
Sbjct: 362 MIEISREVSKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGM 421
Query: 433 VHISEETSQFLGGSYILEEGEE 454
VHIS T L Y+ EEG +
Sbjct: 422 VHISSRTLGLLDNHYVYEEGTD 443
Score = 48.0 bits (109), Expect = 9e-04
Identities = 17/55 (30%), Positives = 35/55 (63%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
++++G+ G V+ G+VG + +D+W + V A++M S+G +H++E T+ L
Sbjct: 961 SLKIGIAHGPVMAGVVGLSKPHYDIWGHTVNMASRMTSTGVRDGIHVTESTANVL 1015
>UniRef50_Q8IGU9 Cluster: RE26442p; n=4; Sophophora|Rep: RE26442p -
Drosophila melanogaster (Fruit fly)
Length = 1162
Score = 91.1 bits (216), Expect = 9e-17
Identities = 37/82 (45%), Positives = 58/82 (70%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+ I++ +R I+MR+GVH+G VL G++G +++FD+WS DV AN++E++G GR
Sbjct: 402 MIKDIRDVREKRHLNIDMRIGVHSGDVLSGVIGAAKWQFDIWSKDVDIANRLEATGATGR 461
Query: 433 VHISEETSQFLGGSYILEEGEE 454
VH+S++T L G Y E+G E
Sbjct: 462 VHVSQKTLSLLDGEYFFEDGTE 483
Score = 54.0 bits (124), Expect = 1e-05
Identities = 18/51 (35%), Positives = 35/51 (68%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETS 440
+R+G+ G + G+VG + +D+W N V A++M+S+G PG++ ++E T+
Sbjct: 1063 LRIGISHGRAMAGVVGISKPHYDIWGNPVNMASRMDSTGVPGQIQVTENTA 1113
Score = 41.5 bits (93), Expect = 0.075
Identities = 24/126 (19%), Positives = 64/126 (50%), Gaps = 6/126 (4%)
Query: 256 CVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNE 315
CV+++G+ LM + +R TF+ Q + L + + ++ S++P ++A L +
Sbjct: 219 CVNLLGIFFRLMRDIALRTTFLDRRQYVEENLLLRYARDQERSLLLSILPAQIADRLQED 278
Query: 316 QVTEADTNVKTY--HNPLNSRISNPGSDIKSLFRPFNMSCM----DNVSILFADIVGFTR 369
+ + + + + ++ R S +K +P + + ++V++L+AD+V +T
Sbjct: 279 VKNRIERSKQQHQQQSQVDLRRSADSQTLKRWRQPDHGTLFIEPHEDVTVLYADVVNYTH 338
Query: 370 MSSMIE 375
+++ ++
Sbjct: 339 LTTTLD 344
>UniRef50_Q17AS9 Cluster: Adenylate cyclase; n=2; Culicidae|Rep:
Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
Length = 1154
Score = 89.4 bits (212), Expect = 3e-16
Identities = 34/82 (41%), Positives = 60/82 (73%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+ I++ R I+MR+G+H+G+++ G++G ++++D+WS DV ANKMES+G+ G+
Sbjct: 408 MIKDIRDVRMSRDLNIDMRIGIHSGSIISGVIGACKWQYDIWSRDVIIANKMESTGEAGK 467
Query: 433 VHISEETSQFLGGSYILEEGEE 454
VH++ +T + L G YI E+G +
Sbjct: 468 VHVTMQTLELLDGEYIYEDGTD 489
Score = 58.4 bits (135), Expect = 6e-07
Identities = 22/74 (29%), Positives = 50/74 (67%), Gaps = 3/74 (4%)
Query: 373 MIEAIQEFDRERGEGIN---MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
+++ +++F E + N +RVG+ G V+ G+VG+ + +D+W N V A++M+S+G
Sbjct: 1034 LMKVLRDFSIENFKQTNPGLLRVGISNGKVMAGVVGSSKPLYDIWGNAVNMASRMDSTGI 1093
Query: 430 PGRVHISEETSQFL 443
PG++ +++E+++ +
Sbjct: 1094 PGKIQVTKESAEII 1107
Score = 41.5 bits (93), Expect = 0.075
Identities = 32/164 (19%), Positives = 81/164 (49%), Gaps = 8/164 (4%)
Query: 218 VILGIIYSIVFEVLNIVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFM 277
+ILG +I + ++ ++ + + ++ LC+++ G++ L+ V +R TF+
Sbjct: 187 IILGGATTICYLIIMALITYRLESDMIIKVTTELIYFLCLNLFGLYFRLINEVAIRRTFL 246
Query: 278 KVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKT-YHNPLN-SRI 335
+ + L+ + +++++ S++P A LM + + +++ +HN +N
Sbjct: 247 DRRELVEGNLLLKFARNQEKELLLSILPEHTA-ELMEKDIRVMIEKMRSGHHNNINPHNF 305
Query: 336 SNPGSDIKSL-----FRPFNMSCMDNVSILFADIVGFTRMSSMI 374
G+ +S+ F + NV+IL+AD+V +T +++ +
Sbjct: 306 FRTGTQWRSINIYLHFSKLYVQKHTNVTILYADVVNYTFITTQL 349
>UniRef50_Q5MAL0 Cluster: Adenylate cyclase; n=2; Eukaryota|Rep:
Adenylate cyclase - Aplysia californica (California sea
hare)
Length = 1339
Score = 87.4 bits (207), Expect = 1e-15
Identities = 40/80 (50%), Positives = 56/80 (70%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+AI + G +NMRVG+HTG VLCG++G +++++DV+SNDV AN ME+ G GR
Sbjct: 374 MIDAIASVCDQTGVKLNMRVGLHTGRVLCGVLGLKKWQYDVFSNDVKLANHMEAGGIAGR 433
Query: 433 VHISEETSQFLGGSYILEEG 452
VHI++ T L G Y +E G
Sbjct: 434 VHITKSTLDQLHGQYEVEPG 453
Score = 66.1 bits (154), Expect = 3e-09
Identities = 56/231 (24%), Positives = 97/231 (41%), Gaps = 26/231 (11%)
Query: 355 DNVSILFADIVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVW 414
D+++ +V F + SM E ++ + +RVG++ G V+ G++G R+ ++D+W
Sbjct: 979 DSITFYLTMLVDF--VMSMKEKLKNINENSYNNFELRVGINVGPVVAGVIGARKPQYDIW 1036
Query: 415 SNDVTFANKMESSGKPGRVHISEETSQFLGGSYILE-EGEEVFGHK----TYFIEGRQVF 469
N V A++MES+G ++ ++EE L + E G+ K TYF+ R+
Sbjct: 1037 GNTVNVASRMESTGVSSKIQVTEEVYAVLKSVFTFECRGKVPVKGKGDMITYFLRERR-- 1094
Query: 470 CPYDREQCLTPSNPVNLRXXXXXXXXXXXXXXXNYFTAPLTPKTEDKLNLRKPNSNNFLS 529
P D P P T ++ + L L P S ++
Sbjct: 1095 RPRDPSCIFPPPTPPESPMVNGSSS---------------TRRSAESLPLTAP-SAAAVT 1138
Query: 530 PTPFNFRA-KASSLPSILDSDTELDDNRDKGLTERTDSSSKSPTSVGSYGK 579
P P + RA + SS+ + +D ER + +PT GS K
Sbjct: 1139 PDPSSKRASECSSITDHQPHSSSMDRRHQASTLERQQKGANTPTPTGSLNK 1189
Score = 46.4 bits (105), Expect = 0.003
Identities = 39/147 (26%), Positives = 65/147 (44%), Gaps = 25/147 (17%)
Query: 236 HLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQL 295
H + W+ + +L LC ++ G+ + T R TF + R ++ + +
Sbjct: 201 HFPDLHWRQ--LVANTILFLCANVAGLFTHNSTDRTQRRTFKDTRDCIAARLDIQDQNEK 258
Query: 296 KEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMD 355
E+++ SV+P +A + N+ + T H+ +F + D
Sbjct: 259 LERILMSVLPQHVAMEMKND--------ITTPHH--------------GMFHKIYIQLHD 296
Query: 356 NVSILFADIVGFTRMSSMIEAIQEFDR 382
NV+ILFADIVGFT +SS A QE R
Sbjct: 297 NVTILFADIVGFTCLSSQCTA-QELVR 322
>UniRef50_A7RRQ7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1052
Score = 87.0 bits (206), Expect = 2e-15
Identities = 43/82 (52%), Positives = 58/82 (70%), Gaps = 2/82 (2%)
Query: 372 SMIEAIQEFDRERGE-GINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
+MI+AI F R+ + +NMRVGVH G V G++G ++++DVWS+DVT AN MES G P
Sbjct: 419 AMIDAIS-FVRDATQVNLNMRVGVHMGKVHSGVLGLVKWQYDVWSDDVTIANHMESGGLP 477
Query: 431 GRVHISEETSQFLGGSYILEEG 452
GRVHI++E L G Y +EEG
Sbjct: 478 GRVHITKEVLDCLNGDYEVEEG 499
Score = 46.4 bits (105), Expect = 0.003
Identities = 16/72 (22%), Positives = 41/72 (56%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M +++ + M++G++ G V+ G++G + ++D+W + V A++M S+GK
Sbjct: 943 AMKRKLEDINLHSFNNFAMKIGLNFGPVVAGVIGAHKPQYDIWGDTVNVASRMYSTGKDN 1002
Query: 432 RVHISEETSQFL 443
+ +++ + L
Sbjct: 1003 HIQVTKAMYEIL 1014
>UniRef50_UPI0000D56082 Cluster: PREDICTED: similar to adenylate
cyclase 8; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to adenylate cyclase 8 - Tribolium castaneum
Length = 912
Score = 85.8 bits (203), Expect = 4e-15
Identities = 36/79 (45%), Positives = 60/79 (75%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+MI+AI++ + I+MR+G+H+G+VLCG++G R+++FD+WS+DV AN+ME++G G
Sbjct: 218 NMIKAIKDTKTKTQVDIDMRIGIHSGSVLCGVLGLRKWQFDIWSHDVKIANRMEATGIAG 277
Query: 432 RVHISEETSQFLGGSYILE 450
RVHIS+ T + L + +E
Sbjct: 278 RVHISDATLRALTKEFRVE 296
Score = 63.3 bits (147), Expect = 2e-08
Identities = 24/69 (34%), Positives = 45/69 (65%)
Query: 375 EAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVH 434
+ ++E +R+ N+RVG+ G ++CG++G ++ FDVW N V A++M+S+G G +
Sbjct: 776 QRLEEINRDSFNRFNLRVGISYGDLVCGVIGAKKPIFDVWGNTVNEASRMDSTGLMGEIQ 835
Query: 435 ISEETSQFL 443
+ + T+Q L
Sbjct: 836 VPKNTAQLL 844
>UniRef50_UPI00005A96A3 Cluster: PREDICTED: similar to adenylate
cyclase 1; n=1; Canis lupus familiaris|Rep: PREDICTED:
similar to adenylate cyclase 1 - Canis familiaris
Length = 546
Score = 85.4 bits (202), Expect = 5e-15
Identities = 36/65 (55%), Positives = 49/65 (75%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSY 447
+N+RVG+HT VLCG++G R++++DVWSNDVT AN ME +G P +VHI+ T L G Y
Sbjct: 162 LNVRVGLHTSRVLCGVLGLRKWQYDVWSNDVTLANVMEVAGLPRKVHITRTTLACLNGDY 221
Query: 448 ILEEG 452
+EEG
Sbjct: 222 EVEEG 226
>UniRef50_Q8IRF5 Cluster: CG32305-PA; n=2; Sophophora|Rep:
CG32305-PA - Drosophila melanogaster (Fruit fly)
Length = 1102
Score = 85.4 bits (202), Expect = 5e-15
Identities = 38/82 (46%), Positives = 50/82 (60%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI Q R IN+R+GVH+G V GI+G +++FD+WS DV N++ESSG PG
Sbjct: 341 MIHITQGVSSRRELDINLRIGVHSGEVFAGIIGHTKWQFDIWSKDVDITNRLESSGLPGL 400
Query: 433 VHISEETSQFLGGSYILEEGEE 454
VH+S+ T L YI EG E
Sbjct: 401 VHVSQRTLSMLDEHYIFREGTE 422
Score = 45.2 bits (102), Expect = 0.006
Identities = 15/55 (27%), Positives = 35/55 (63%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
++++G+ G+V+ G+VG + +D+W + V A++M S+G + ++ T++ L
Sbjct: 939 SLKIGISHGSVMAGVVGLSKPHYDIWGHTVNMASRMSSTGLLDNIQVTRHTAKVL 993
>UniRef50_Q4RR06 Cluster: Chromosome 14 SCAF15003, whole genome
shotgun sequence; n=7; Clupeocephala|Rep: Chromosome 14
SCAF15003, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1077
Score = 85.0 bits (201), Expect = 6e-15
Identities = 36/81 (44%), Positives = 57/81 (70%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+MI I+ ++ ++MR+G+H+G+VLCG++G ++++FDVWS DV AN +E+ G PG
Sbjct: 376 AMINTIRYVRKQLKFEVDMRIGIHSGSVLCGVLGLQKWQFDVWSWDVGIANMLEAGGIPG 435
Query: 432 RVHISEETSQFLGGSYILEEG 452
R+HIS T L G+Y E+G
Sbjct: 436 RIHISRATLDCLEGTYKTEDG 456
Score = 63.7 bits (148), Expect = 2e-08
Identities = 27/86 (31%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M E ++E +R + +RVG+ G V+ G++G + ++D+W + V A++M+S+G G
Sbjct: 934 AMQETLKEINRHSTKNFQLRVGIAHGPVVAGVIGATKPQYDIWGSTVNLASRMDSTGVSG 993
Query: 432 RVHISEETSQFL-GGSYILEEGEEVF 456
R+ + E T + L ++LE E+F
Sbjct: 994 RIQVPEATKKILTEWGFVLELRGEIF 1019
Score = 41.1 bits (92), Expect = 0.099
Identities = 37/137 (27%), Positives = 68/137 (49%), Gaps = 8/137 (5%)
Query: 247 MFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPP 306
+F + LL L ++ G+ I+ +T R F++ + + R +LE E Q +E+++ S++P
Sbjct: 185 VFAKGLLCLGMNTAGLFIHYLTDHAQRQVFLETRRCIEGRLKLEQENQRQERLVLSILPR 244
Query: 307 KLA------SNLMNEQVTEADTNVKTYHNPLNSR-ISNPGSDIKSLFRPFNMSCMDNVSI 359
+A N + ++++ + + H + R + + S L F S SI
Sbjct: 245 FVALEMIADMNCLEDELSPQEFHKIYIHQYKDVRYVHSLYSSSPRLLAWFPHSS-GLCSI 303
Query: 360 LFADIVGFTRMSSMIEA 376
LFADI GFT +S + A
Sbjct: 304 LFADIKGFTLLSMNLSA 320
>UniRef50_Q9VK53 Cluster: CG5983-PA, isoform A; n=13;
Sophophora|Rep: CG5983-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 1130
Score = 85.0 bits (201), Expect = 6e-15
Identities = 39/84 (46%), Positives = 54/84 (64%), Gaps = 1/84 (1%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SMI IQE ERG I+MR+GVH+G++L GI+G + +FD+W DV AN +ES+G+PG
Sbjct: 390 SMISNIQEVRAERGLDIDMRIGVHSGSLLAGIIGEAKLQFDIWGTDVEIANHLESTGEPG 449
Query: 432 RVHISEETSQFLG-GSYILEEGEE 454
VH+S T L Y + G +
Sbjct: 450 YVHVSGRTLSMLNPADYTILSGTQ 473
Score = 59.3 bits (137), Expect = 3e-07
Identities = 22/64 (34%), Positives = 43/64 (67%), Gaps = 1/64 (1%)
Query: 380 FDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
F+R +G + +G+ +G ++ G+VG + +D+W N V A++MES+G PG + ++EE+
Sbjct: 997 FERSLSQG-KICIGISSGEIMAGVVGASQPHYDIWGNPVNMASRMESTGLPGHIQVTEES 1055
Query: 440 SQFL 443
++ L
Sbjct: 1056 AKIL 1059
>UniRef50_UPI0000DB7252 Cluster: PREDICTED: similar to ACXD
CG5712-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
to ACXD CG5712-PA - Apis mellifera
Length = 1051
Score = 84.2 bits (199), Expect = 1e-14
Identities = 32/58 (55%), Positives = 47/58 (81%)
Query: 382 RERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
RE G +NMR+GVH+G ++ GI+G ++++DVWS DV ANKME +GKPG+VHI+++T
Sbjct: 321 RESGVDVNMRIGVHSGNIISGILGVSKWQYDVWSRDVVIANKMEQTGKPGKVHITQQT 378
Score = 52.8 bits (121), Expect = 3e-05
Identities = 19/54 (35%), Positives = 37/54 (68%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+R+G+ G V G+VG ++ +D+W + V A++M+++G PG++ I+ ET+ L
Sbjct: 953 LRIGISHGEVTAGVVGAQKPLYDIWGDAVNMASRMDTTGVPGKIQITAETAAVL 1006
Score = 37.1 bits (82), Expect = 1.6
Identities = 33/155 (21%), Positives = 75/155 (48%), Gaps = 13/155 (8%)
Query: 218 VILGIIYSIVFEV-LNIVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTF 276
+ILGI + + V L+++ + + ++ + + +CV+ +G++ M + R +F
Sbjct: 104 LILGITTTTCYLVALSLITYRNSFDFSTK-IITDTIYFVCVNGLGLYFRFMNEIVTRRSF 162
Query: 277 MKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRIS 336
+ + + +L EK +E++ S++P +A+ + E + ++ + P
Sbjct: 163 LDHRKCVESTLRLNYEKDQEEQLTRSILPQHIAAKIKKE-FRDIFKFLEEHKKP-----P 216
Query: 337 NPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMS 371
P S F + +NVSIL+AD+V F+ ++
Sbjct: 217 KPSS-----FSDLCVETHNNVSILYADVVNFSGLT 246
>UniRef50_UPI00015B5520 Cluster: PREDICTED: similar to adenylate
cyclase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to adenylate cyclase - Nasonia vitripennis
Length = 1092
Score = 83.4 bits (197), Expect = 2e-14
Identities = 34/75 (45%), Positives = 55/75 (73%), Gaps = 1/75 (1%)
Query: 370 MSSMIEAIQ-EFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSG 428
M ++I A++ RE G +NMR+GVH+G ++ GI+GT ++++DVWS DV ANKME +G
Sbjct: 387 MINIINAVRARVQRESGVDVNMRIGVHSGKIISGILGTNKWQYDVWSRDVIIANKMEQTG 446
Query: 429 KPGRVHISEETSQFL 443
+ G+VH++++T L
Sbjct: 447 EAGKVHVTQQTLDLL 461
Score = 52.0 bits (119), Expect = 5e-05
Identities = 18/73 (24%), Positives = 44/73 (60%)
Query: 371 SSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
+ M+ ++ + +R+G+ G V G+VG ++ +D+W + V A++M+++G+
Sbjct: 976 AEMMYVLESIKMQTTRPYKLRIGIAHGEVTAGVVGAQKPLYDIWGDAVNMASRMDTTGEV 1035
Query: 431 GRVHISEETSQFL 443
G++ ++ ET++ L
Sbjct: 1036 GKIQVTTETAEVL 1048
Score = 44.8 bits (101), Expect = 0.008
Identities = 31/121 (25%), Positives = 59/121 (48%), Gaps = 9/121 (7%)
Query: 251 ILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLAS 310
++ CV+ +G++ M + R +F+ + + +L EK +E++ S++PP A+
Sbjct: 214 VIYHTCVNCLGLYFRFMNEIMTRRSFLDRRKCVESTLRLNYEKDQEEQLTRSILPPHFAA 273
Query: 311 NLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRM 370
+ N + L I SD +LFR + +NVSIL+AD+V F+ +
Sbjct: 274 KIKK--------NFRDILTFLPVLIIKFISDC-ALFRDLYVETHENVSILYADVVNFSGL 324
Query: 371 S 371
+
Sbjct: 325 T 325
>UniRef50_A0YU66 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC
8106|Rep: Adenylate cyclase - Lyngbya sp. PCC 8106
Length = 833
Score = 82.6 bits (195), Expect = 3e-14
Identities = 40/101 (39%), Positives = 62/101 (61%), Gaps = 5/101 (4%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SM + F + GE + +R+G+HTGTV+ G++GT +F +D+W + V A +MESSGKPG
Sbjct: 733 SMQLVVDHFPFDYGETLQIRIGIHTGTVVAGVIGTHKFIYDLWGDTVNIAYRMESSGKPG 792
Query: 432 RVHISEETSQFLGGSYILEE-GEEVFGHK----TYFIEGRQ 467
++ ++ + L YI E+ GE K TY++ GRQ
Sbjct: 793 KIQVTAAVYERLKNEYIFEKRGEIPIKGKGKMMTYWLIGRQ 833
>UniRef50_UPI00006CB3C2 Cluster: Adenylate and Guanylate cyclase
catalytic domain containing protein; n=1; Tetrahymena
thermophila SB210|Rep: Adenylate and Guanylate cyclase
catalytic domain containing protein - Tetrahymena
thermophila SB210
Length = 2982
Score = 80.2 bits (189), Expect = 2e-13
Identities = 38/100 (38%), Positives = 64/100 (64%), Gaps = 5/100 (5%)
Query: 372 SMIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
+M+E I++ E E +NMR+G+HTG ++ GI G+ ++D++ DV +NKMES+G+P
Sbjct: 2800 NMLEIIKQVRSEVNFETLNMRIGIHTGQIIGGITGSDIVRYDIYGTDVMLSNKMESNGEP 2859
Query: 431 GRVHISEETSQFL----GGSYILEEGEEVFGHKTYFIEGR 466
G++ +S+ T L G Y ++G+EV + YFI+ R
Sbjct: 2860 GKIMVSQTTKDLLESAYGSYYQFQQGKEVHDIQGYFIQRR 2899
Score = 45.2 bits (102), Expect = 0.006
Identities = 17/63 (26%), Positives = 37/63 (58%)
Query: 383 ERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQF 442
+ G+ + +++G+H G V+ G++G + +F + + V +++ S G P V ISE+ +
Sbjct: 1986 QNGKNLELKIGIHYGQVIAGVIGHHKPQFSLIGDTVNTTSRVCSKGNPSEVTISEQAFEK 2045
Query: 443 LGG 445
+ G
Sbjct: 2046 IQG 2048
>UniRef50_A5P0P3 Cluster: Response regulator receiver protein; n=1;
Methylobacterium sp. 4-46|Rep: Response regulator
receiver protein - Methylobacterium sp. 4-46
Length = 531
Score = 78.2 bits (184), Expect = 7e-13
Identities = 32/75 (42%), Positives = 49/75 (65%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+ ++E R G + +RVG+H+G + G++G RF +DVW + V A +MES G+ GR
Sbjct: 427 MMADVEEVGRALGVELAVRVGIHSGEAVAGVIGQSRFAYDVWGDSVNIAARMESHGQAGR 486
Query: 433 VHISEETSQFLGGSY 447
+HISE T + LGG +
Sbjct: 487 IHISESTRRALGGDF 501
>UniRef50_A0C5Y1 Cluster: Chromosome undetermined scaffold_151, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_151, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2641
Score = 78.2 bits (184), Expect = 7e-13
Identities = 37/76 (48%), Positives = 53/76 (69%), Gaps = 1/76 (1%)
Query: 373 MIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
MIE I+ + G +G++MR+G+HTG V+ GI+GT ++DV+ DV +NKMES+G+ G
Sbjct: 2517 MIEIIRNVRQIIGFDGLDMRIGIHTGKVIAGILGTEIVRYDVYGADVMISNKMESNGEKG 2576
Query: 432 RVHISEETSQFLGGSY 447
RV +SEET Q L Y
Sbjct: 2577 RVQVSEETKQLLEIQY 2592
Score = 38.7 bits (86), Expect = 0.53
Identities = 14/51 (27%), Positives = 33/51 (64%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEE 438
+ +++G+H G V+ G++G + +F + + V +++ S+G+ G+V +S E
Sbjct: 1897 LTIKIGIHYGRVIAGVIGHHKPQFSLIGDTVNTTSRVCSTGQDGQVTLSNE 1947
>UniRef50_Q23TD7 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Adenylate and Guanylate cyclase catalytic
domain containing protein - Tetrahymena thermophila SB210
Length = 2945
Score = 77.8 bits (183), Expect = 9e-13
Identities = 37/79 (46%), Positives = 54/79 (68%), Gaps = 3/79 (3%)
Query: 372 SMIEAIQEFDRERGE--GINMRVGVHTGT-VLCGIVGTRRFKFDVWSNDVTFANKMESSG 428
SMI+ I+ RE + +NMR+G+H G VL GI+GT ++D++ DV ANKMES+G
Sbjct: 2820 SMIQVIENIKREHEDFKSVNMRIGIHLGEKVLGGIIGTNIVRYDIFGKDVVIANKMESNG 2879
Query: 429 KPGRVHISEETSQFLGGSY 447
+ GR++ISE+T +FL Y
Sbjct: 2880 QLGRINISEDTKKFLENHY 2898
Score = 38.7 bits (86), Expect = 0.53
Identities = 16/56 (28%), Positives = 34/56 (60%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLG 444
++++G+H G V+ G++G + +F + + V A+++ S K R+ +S E + LG
Sbjct: 2182 DVKIGIHYGKVIAGVIGAHKPQFSLIGDTVNTASRVCSKCKEKRISLSYEAHRRLG 2237
>UniRef50_UPI00006CB738 Cluster: Adenylate and Guanylate cyclase
catalytic domain containing protein; n=1; Tetrahymena
thermophila SB210|Rep: Adenylate and Guanylate cyclase
catalytic domain containing protein - Tetrahymena
thermophila SB210
Length = 2700
Score = 77.4 bits (182), Expect = 1e-12
Identities = 40/87 (45%), Positives = 53/87 (60%), Gaps = 4/87 (4%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MIE I +NMR+G+HTG ++ GI+GT ++DV+ DV ANKMES+G+PG+
Sbjct: 2593 MIETINIIKGTAYPFLNMRIGIHTGKIIGGIMGTDVVRYDVYGKDVMIANKMESNGEPGK 2652
Query: 433 VHISEETSQFLG----GSYILEEGEEV 455
V ISE T Q L Y + EG EV
Sbjct: 2653 VMISESTKQMLEKGEVNEYNITEGNEV 2679
>UniRef50_Q8YZ26 Cluster: Adenylate cyclase; n=1; Nostoc sp. PCC
7120|Rep: Adenylate cyclase - Anabaena sp. (strain PCC
7120)
Length = 472
Score = 76.6 bits (180), Expect = 2e-12
Identities = 27/79 (34%), Positives = 55/79 (69%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
+++AI +F+ + GE +R+G+++G V+ G++G ++F +D+W + V A++MES G P R
Sbjct: 368 ILDAIAQFNLDTGEQFKIRIGINSGPVVAGVIGIKKFIYDLWGDTVNIASRMESHGTPNR 427
Query: 433 VHISEETSQFLGGSYILEE 451
+H+S + + L S++ E+
Sbjct: 428 IHVSAASHELLKDSFLFED 446
>UniRef50_A0BG69 Cluster: Chromosome undetermined scaffold_105, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_105, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2473
Score = 76.6 bits (180), Expect = 2e-12
Identities = 36/76 (47%), Positives = 54/76 (71%), Gaps = 1/76 (1%)
Query: 373 MIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
MI+ I++ G +G++MR+G+HTG V+ GI+GT ++DV+ DV +NKMES+G+ G
Sbjct: 2340 MIDIIRQVRSIIGFDGLDMRIGIHTGKVIGGILGTEIVRYDVYGADVMISNKMESNGERG 2399
Query: 432 RVHISEETSQFLGGSY 447
+V +SEET Q L SY
Sbjct: 2400 KVQVSEETKQLLEQSY 2415
Score = 42.3 bits (95), Expect = 0.043
Identities = 17/66 (25%), Positives = 39/66 (59%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+E ++F + + +++GVH G V+ G++G + +F + + V +++ S+G+ G
Sbjct: 1710 MMEYAKKFKFGQSGNVKIKIGVHYGRVIAGVIGHHKPQFSLIGDTVNTTSRVCSTGQDGE 1769
Query: 433 VHISEE 438
+ +S E
Sbjct: 1770 ITLSNE 1775
>UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein;
n=1; Tetrahymena thermophila SB210|Rep: Sodium/calcium
exchanger protein - Tetrahymena thermophila SB210
Length = 5392
Score = 76.2 bits (179), Expect = 3e-12
Identities = 33/76 (43%), Positives = 53/76 (69%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
SMI++I E + I+MR+G+HTG ++ G++GT ++D++ +V ANKMES+G+ G
Sbjct: 4156 SMIKSIDEMKKREFSDIDMRIGIHTGDIIGGVIGTDIVRYDIYGPNVLIANKMESNGERG 4215
Query: 432 RVHISEETSQFLGGSY 447
RV ISE T + + GS+
Sbjct: 4216 RVMISETTYKLVKGSF 4231
Score = 46.0 bits (104), Expect = 0.003
Identities = 18/56 (32%), Positives = 36/56 (64%)
Query: 383 ERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEE 438
E GE I +++G+H G V+ G++G + +F + + V +++ S+ +PG V +SE+
Sbjct: 2535 EDGEKIQLKIGIHFGNVIAGVIGYHKPQFSLIGDTVNTTSRVCSTSEPGTVTLSEQ 2590
>UniRef50_A0YIQ8 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC
8106|Rep: Adenylate cyclase - Lyngbya sp. PCC 8106
Length = 358
Score = 76.2 bits (179), Expect = 3e-12
Identities = 36/100 (36%), Positives = 62/100 (62%), Gaps = 5/100 (5%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M + I F RE + +N+R+G++TG V+ G++G ++F +D+W + V A++MES GK G
Sbjct: 249 MQQEIYRFKREDNKILNIRIGINTGPVVAGVIGLKKFSYDLWGDAVNIASRMESHGKIGE 308
Query: 433 VHISEETSQFLGGSYILEEG--EEVFGHK---TYFIEGRQ 467
+ +S T + L Y+LE+ +V G TY+++ RQ
Sbjct: 309 IQVSSSTYELLKHKYVLEKRGIVQVKGRGEMITYWLKSRQ 348
>UniRef50_A0DTD8 Cluster: Chromosome undetermined scaffold_63, whole
genome shotgun sequence; n=6; Eukaryota|Rep: Chromosome
undetermined scaffold_63, whole genome shotgun sequence -
Paramecium tetraurelia
Length = 2465
Score = 76.2 bits (179), Expect = 3e-12
Identities = 32/62 (51%), Positives = 46/62 (74%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGG 445
+G++MR+G+HTG VL G++GT ++D++ DV ANKMES+GK G+VH+SE T Q L
Sbjct: 2351 DGLDMRIGIHTGCVLGGVMGTDIVRYDIYGPDVLIANKMESNGKKGQVHVSEITKQLLEQ 2410
Query: 446 SY 447
Y
Sbjct: 2411 DY 2412
>UniRef50_Q7WWV9 Cluster: Putative regulatory protein; n=1;
Ralstonia eutropha H16|Rep: Putative regulatory protein
- Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428
/ Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 412
Score = 75.8 bits (178), Expect = 4e-12
Identities = 34/100 (34%), Positives = 61/100 (61%), Gaps = 5/100 (5%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M +A+ F++ G + MR+G+++G V+ G++G R+F +D+W V A++MES G G
Sbjct: 307 NMSDALMHFNQHTGFNLQMRIGINSGAVVAGVIGKRKFIYDLWGAAVNIASRMESHGVAG 366
Query: 432 RVHISEETSQFLGGSYILE-----EGEEVFGHKTYFIEGR 466
RV +++ T + LG S+ E E + + T+F+ GR
Sbjct: 367 RVQVTDATRRLLGESFQFEERGSIEAKGIGALHTWFLTGR 406
>UniRef50_A0CKZ5 Cluster: Chromosome undetermined scaffold_20, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_20, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2620
Score = 75.4 bits (177), Expect = 5e-12
Identities = 35/77 (45%), Positives = 52/77 (67%), Gaps = 1/77 (1%)
Query: 372 SMIEAIQEFDRE-RGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
SMIE I + ++ + + +NMR+GVHTG VL G+VGT ++D++ DVT AN MESSG+
Sbjct: 2508 SMIEIINHYKKDPQYQHLNMRIGVHTGRVLGGVVGTDVVRYDIYGEDVTIANLMESSGQE 2567
Query: 431 GRVHISEETSQFLGGSY 447
G++ +SE T + Y
Sbjct: 2568 GKILVSEITKNLVENEY 2584
Score = 41.5 bits (93), Expect = 0.075
Identities = 15/65 (23%), Positives = 38/65 (58%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+E ++ + + +++G+H G V+ G++G + +F + + V +++ S+G+ G
Sbjct: 1733 MMETVKTMKYGDNQDVQLKIGIHYGRVIAGVIGVHKPQFSLIGDTVNTTSRVCSTGEAGF 1792
Query: 433 VHISE 437
+ +SE
Sbjct: 1793 ITLSE 1797
Score = 35.9 bits (79), Expect = 3.7
Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 7/70 (10%)
Query: 308 LASNLMNEQVTEADTNVKTYHNPLNS--RISNPGSDIKSLFRPFNMSCMDNVSILFADIV 365
L S ++ Q+ + + N+ Y P ++ R+ NP + F M ++N ++LFADI
Sbjct: 2384 LISLQLSTQIAKYE-NMLQYLMPPHALRRLLNPDQENTDTF----MDVLENATVLFADIA 2438
Query: 366 GFTRMSSMIE 375
GFT+ SS +E
Sbjct: 2439 GFTKYSSSVE 2448
>UniRef50_Q8F690 Cluster: Adenylate cyclase; n=4; Leptospira|Rep:
Adenylate cyclase - Leptospira interrogans
Length = 492
Score = 74.9 bits (176), Expect = 7e-12
Identities = 28/79 (35%), Positives = 51/79 (64%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+ +++ + N+R+G+HTG V+ G++G +F +D+W + V A++MES G+PGR
Sbjct: 393 MIQGLKDLQKSWKYEFNIRIGIHTGDVVAGVIGKNKFVYDLWGDSVNTASRMESHGEPGR 452
Query: 433 VHISEETSQFLGGSYILEE 451
+H SE + + ++ EE
Sbjct: 453 IHCSEAVYESIKDLFLFEE 471
>UniRef50_Q394B3 Cluster: Adenylate/guanylate cyclase; n=4;
Burkholderiaceae|Rep: Adenylate/guanylate cyclase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 395
Score = 74.9 bits (176), Expect = 7e-12
Identities = 34/104 (32%), Positives = 62/104 (59%), Gaps = 5/104 (4%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+A+ F+ R + +R+G+++G V+ G++G R+F +D+W V A++MES G GR
Sbjct: 291 MIDALARFNAARHCNLKLRIGINSGEVVAGVIGKRKFIYDLWGAAVNLASRMESQGVAGR 350
Query: 433 VHISEETSQFLGGSYILEE-----GEEVFGHKTYFIEGRQVFCP 471
V +++ T LG +++ EE + + +T+F+ GR P
Sbjct: 351 VQVTDATRVMLGEAFVFEERGLIAAKGMGEFRTWFVVGRAGLSP 394
>UniRef50_Q238W6 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Adenylate and Guanylate cyclase catalytic
domain containing protein - Tetrahymena thermophila SB210
Length = 2814
Score = 73.7 bits (173), Expect = 2e-11
Identities = 33/80 (41%), Positives = 55/80 (68%), Gaps = 1/80 (1%)
Query: 372 SMIEAIQEFDRE-RGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
+MIE I++ + + E ++MR+GVHTG ++ G++GT ++D++ DV ANKMESSG+
Sbjct: 2528 NMIEIIKQLRAQVKFESLDMRIGVHTGKIIGGVIGTDIVRYDIYGRDVVIANKMESSGEQ 2587
Query: 431 GRVHISEETSQFLGGSYILE 450
GR+ +S +T + L S I +
Sbjct: 2588 GRILVSSQTRKLLEPSGIFD 2607
Score = 39.1 bits (87), Expect = 0.40
Identities = 13/56 (23%), Positives = 35/56 (62%)
Query: 383 ERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEE 438
+ G+ + +++G+H G V+ G++G + +F + + + +++ S+G+ R+ IS +
Sbjct: 1860 KHGDKMRVKIGIHYGRVMAGVIGYHKPQFSLIGDTINTTSRVMSTGEDNRMTISSQ 1915
>UniRef50_Q8F1T7 Cluster: Adenylate cyclase; n=2; Leptospira
interrogans|Rep: Adenylate cyclase - Leptospira
interrogans
Length = 418
Score = 73.3 bits (172), Expect = 2e-11
Identities = 37/102 (36%), Positives = 63/102 (61%), Gaps = 9/102 (8%)
Query: 373 MIEAIQEFDRERGE-GIN---MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSG 428
M +AIQ+ E+ + GI+ +R+G HTG V G++G +F +D+W + V A++MESSG
Sbjct: 298 MCDAIQKLKEEKNKNGISYWDVRIGFHTGPVAAGVIGKNKFSYDIWGDTVNIASRMESSG 357
Query: 429 KPGRVHISEETSQFLGGSY-ILEEGEEVFGHK----TYFIEG 465
+PG++++SEE+ + L + G+ +K YF+EG
Sbjct: 358 EPGKINVSEESYKLLSPFFTFTSRGKIAAKNKGEISMYFLEG 399
>UniRef50_UPI00015B5C60 Cluster: PREDICTED: similar to soluble
guanylyl cyclase alpha 1 subunit; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to soluble guanylyl
cyclase alpha 1 subunit - Nasonia vitripennis
Length = 705
Score = 72.1 bits (169), Expect = 5e-11
Identities = 36/81 (44%), Positives = 53/81 (65%), Gaps = 2/81 (2%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+ + G+ I MR+G+HTG VL G+VG + ++ ++ ++VT ANK ESS +P R
Sbjct: 573 MIQTCTQHSTHDGKPIKMRIGIHTGMVLAGVVGKKMPRYCLFGHNVTIANKFESSSEPLR 632
Query: 433 VHISEETSQFL--GGSYILEE 451
V+IS T +FL G +ILEE
Sbjct: 633 VNISPTTYEFLMQGPGFILEE 653
>UniRef50_A0E8U0 Cluster: Cation-transporting ATPase; n=4; Paramecium
tetraurelia|Rep: Cation-transporting ATPase - Paramecium
tetraurelia
Length = 2302
Score = 72.1 bits (169), Expect = 5e-11
Identities = 32/72 (44%), Positives = 50/72 (69%), Gaps = 1/72 (1%)
Query: 373 MIEAIQEFDRE-RGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
M+E I + + + + +NMR+G+HTG V GI+GT ++D++ DV+ ANKMESSG+ G
Sbjct: 2187 MVEIIMQVRLKIKFDKLNMRIGIHTGQVTGGIIGTDIVRYDIYGKDVSIANKMESSGEEG 2246
Query: 432 RVHISEETSQFL 443
RV +S+ T Q +
Sbjct: 2247 RVQVSQTTKQMI 2258
Score = 45.6 bits (103), Expect = 0.005
Identities = 18/66 (27%), Positives = 39/66 (59%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M++ +Q +G I M++G+H G V+ G++G + +F + + V +++ S+G G
Sbjct: 1653 MMQQVQGRKYGKGNQIEMKIGIHVGRVIAGVIGHHKPQFSLIGDPVNQTSRVGSTGDTGA 1712
Query: 433 VHISEE 438
+ +SE+
Sbjct: 1713 ITLSEQ 1718
>UniRef50_A0YSC8 Cluster: Extracellular ligand-binding receptor; n=3;
Bacteria|Rep: Extracellular ligand-binding receptor -
Lyngbya sp. PCC 8106
Length = 1301
Score = 71.7 bits (168), Expect = 6e-11
Identities = 35/100 (35%), Positives = 60/100 (60%), Gaps = 5/100 (5%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M I F R G +R+G++TG V+ G++GTR+F +D+W + V A++MES G+ G+
Sbjct: 1202 MQREICRFQRHDGLPFRLRIGINTGPVVAGVIGTRKFIYDLWGDAVNVASRMESHGEAGK 1261
Query: 433 VHISEETSQFLGGSYILEEGE--EVFG---HKTYFIEGRQ 467
+ +++ T L YI E+ +V G TY+++GR+
Sbjct: 1262 IQVTKATYDLLKDQYIFEKRGIIDVKGIGRMATYWLQGRK 1301
>UniRef50_Q10XK8 Cluster: Adenylate/guanylate cyclase precursor; n=1;
Trichodesmium erythraeum IMS101|Rep: Adenylate/guanylate
cyclase precursor - Trichodesmium erythraeum (strain
IMS101)
Length = 1209
Score = 71.3 bits (167), Expect = 8e-11
Identities = 33/101 (32%), Positives = 61/101 (60%), Gaps = 5/101 (4%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M E + F + + +R+G++TG V+ G++G ++F +D+W + V A++MES G PG
Sbjct: 1107 MREELAHFAHKSKQDFLIRIGINTGPVVAGVIGRKKFIYDLWGDTVNIASRMESQGIPGV 1166
Query: 433 VHISEETSQFLGGSYILEEGEEVF----GH-KTYFIEGRQV 468
+ ++E T Q L ++ E + G+ KTYF++G++V
Sbjct: 1167 IQVTEATYQILKHKFLFTERGLIHIKGKGYMKTYFLQGKKV 1207
>UniRef50_A0CQM4 Cluster: Chromosome undetermined scaffold_24, whole
genome shotgun sequence; n=5; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_24, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2488
Score = 71.3 bits (167), Expect = 8e-11
Identities = 30/72 (41%), Positives = 51/72 (70%), Gaps = 1/72 (1%)
Query: 373 MIEAIQEFDRE-RGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
MI+ IQ+ +++ + + +NMR+G HTG V+ G+VGT ++D++ DVT ANKMES G+ G
Sbjct: 2376 MIQIIQQINKDPQFQHLNMRIGAHTGRVIGGVVGTDVVRYDIYGEDVTTANKMESKGQEG 2435
Query: 432 RVHISEETSQFL 443
++ +S+ T +
Sbjct: 2436 KIMVSQATKDLI 2447
Score = 39.5 bits (88), Expect = 0.30
Identities = 19/92 (20%), Positives = 52/92 (56%), Gaps = 5/92 (5%)
Query: 347 RPFNMSCMDNVSILFADIVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGT 406
+ +NMS DN++ + +M ++ ++ D++ + +++G+H G V+ G++G
Sbjct: 1630 KDYNMS--DNLNPTERILDAALQMQESVKTMKYGDKK---AVILKIGIHYGRVIAGVIGA 1684
Query: 407 RRFKFDVWSNDVTFANKMESSGKPGRVHISEE 438
+ +F + + V +++ S+ +PG + +S++
Sbjct: 1685 HKPQFSLIGDTVNTTSRVCSTSEPGIITLSQQ 1716
>UniRef50_Q0LMK3 Cluster: Adenylyl cyclase class-3/4/guanylyl
cyclase; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
Adenylyl cyclase class-3/4/guanylyl cyclase -
Herpetosiphon aurantiacus ATCC 23779
Length = 355
Score = 70.9 bits (166), Expect = 1e-10
Identities = 27/73 (36%), Positives = 47/73 (64%)
Query: 371 SSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
+SM+ I++ G+ + MR+G+H+G V+ G++GT +F +D+W + V A++MESS P
Sbjct: 250 TSMLAEIEQITMPNGKPLQMRIGIHSGPVVAGVIGTIKFSYDLWGDTVNIASRMESSAHP 309
Query: 431 GRVHISEETSQFL 443
+ +S ET L
Sbjct: 310 NTIQVSAETYALL 322
>UniRef50_Q22AU0 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=2; Tetrahymena|Rep:
Adenylate and Guanylate cyclase catalytic domain
containing protein - Tetrahymena thermophila SB210
Length = 2450
Score = 70.9 bits (166), Expect = 1e-10
Identities = 36/109 (33%), Positives = 64/109 (58%), Gaps = 4/109 (3%)
Query: 343 KSLFRPFNMSCMDNVS--ILFADIVGFTRMS-SMIEAIQEF-DRERGEGINMRVGVHTGT 398
+++++ + + M N++ I+ + M SMI+ IQ D+ + MR+G+HTG
Sbjct: 2313 RNVYKVYTIGGMTNINNRIIHEEAKNVVDMGFSMIKTIQYVRDKVNNSDLQMRIGIHTGK 2372
Query: 399 VLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSY 447
+L GI+GT ++D++ DV ANK+ES+G G++ +SE T L +Y
Sbjct: 2373 ILGGILGTNIVRYDIFGKDVMIANKVESNGVGGQISVSEATKVLLENNY 2421
>UniRef50_A0DVQ1 Cluster: Chromosome undetermined scaffold_66, whole
genome shotgun sequence; n=5; Alveolata|Rep: Chromosome
undetermined scaffold_66, whole genome shotgun sequence -
Paramecium tetraurelia
Length = 2408
Score = 70.9 bits (166), Expect = 1e-10
Identities = 33/76 (43%), Positives = 50/76 (65%), Gaps = 1/76 (1%)
Query: 373 MIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
MI+ I + ++ EG+NMR+GVHTG V G++GT ++D++ DV ANKMES+G G
Sbjct: 2292 MIKIITQVRKQINFEGLNMRIGVHTGPVFGGVMGTDIVRYDIYGPDVLIANKMESNGVKG 2351
Query: 432 RVHISEETSQFLGGSY 447
V +S+ T ++L Y
Sbjct: 2352 NVQVSQSTKKYLEELY 2367
>UniRef50_Q8F778 Cluster: Adenylate cyclase; n=3; Leptospira
interrogans|Rep: Adenylate cyclase - Leptospira
interrogans
Length = 366
Score = 70.5 bits (165), Expect = 1e-10
Identities = 27/61 (44%), Positives = 47/61 (77%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYIL 449
+R+G+H+G+V+ G+VGT++F +D+W + V A++MESSG PG V+IS+ET + + +I
Sbjct: 254 LRLGIHSGSVVAGVVGTKKFAYDIWGDSVNTASRMESSGIPGEVNISQETFEKIKDFFIC 313
Query: 450 E 450
+
Sbjct: 314 D 314
>UniRef50_A7BXS6 Cluster: Adenylate/guanylate cyclase; n=1;
Beggiatoa sp. PS|Rep: Adenylate/guanylate cyclase -
Beggiatoa sp. PS
Length = 430
Score = 70.5 bits (165), Expect = 1e-10
Identities = 35/101 (34%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M EA+ +F+R + +R+G+H G V+ G++G ++F +D+W + V A++MES G G
Sbjct: 330 MQEALAQFNRRYHYDLKIRIGIHNGAVVAGVIGLKKFAYDLWGDTVNTASRMESHGIAGC 389
Query: 433 VHISEETSQFLGGSYIL-EEGE-EVFGHK---TYFIEGRQV 468
+ +S L Y+L + G E+ G TY ++GRQV
Sbjct: 390 IQVSNRVYDALEDKYVLTKRGTIEIKGKGEMITYMLKGRQV 430
>UniRef50_A0C7P7 Cluster: Chromosome undetermined scaffold_156, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_156, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2354
Score = 70.5 bits (165), Expect = 1e-10
Identities = 28/60 (46%), Positives = 44/60 (73%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSY 447
INMR+G+HTG ++ GIVGT ++D++ +DV A KME + + GR+ +SE+T +FL +Y
Sbjct: 2264 INMRIGIHTGNIIGGIVGTDIVRYDIYGSDVAIAKKMEQNSQIGRIMVSEDTMKFLDATY 2323
>UniRef50_A0EHP6 Cluster: Cation-transporting ATPase; n=3; Paramecium
tetraurelia|Rep: Cation-transporting ATPase - Paramecium
tetraurelia
Length = 2285
Score = 70.1 bits (164), Expect = 2e-10
Identities = 34/69 (49%), Positives = 47/69 (68%), Gaps = 1/69 (1%)
Query: 372 SMIEAIQEFDRERGEGI-NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
SMIE I E + + NMR+G+HTG+++ GI+GT ++D++ DV+ ANKMESSG
Sbjct: 2153 SMIEIIMEVRKLIDFPLLNMRIGIHTGSIIGGIIGTDIVRYDIYGQDVSIANKMESSGSE 2212
Query: 431 GRVHISEET 439
G V ISE T
Sbjct: 2213 GHVQISETT 2221
Score = 45.6 bits (103), Expect = 0.005
Identities = 20/66 (30%), Positives = 38/66 (57%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+E IQ +G I M++G+H G V+ G++G + +F + + V +++ S+G G
Sbjct: 1614 MMEQIQGRQYGKGNQIEMKIGIHVGRVIAGLIGHHKPQFSLIGDPVNQTSRVGSTGDVGA 1673
Query: 433 VHISEE 438
+ +S E
Sbjct: 1674 ITLSAE 1679
>UniRef50_Q6BG52 Cluster: Guanylyl cyclase, putative; n=4; Paramecium
tetraurelia|Rep: Guanylyl cyclase, putative - Paramecium
tetraurelia
Length = 2634
Score = 69.7 bits (163), Expect = 2e-10
Identities = 33/76 (43%), Positives = 50/76 (65%), Gaps = 1/76 (1%)
Query: 373 MIEAIQEFDRE-RGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
MI+ I + ++ + + +NMR+GVHTG VL G+VGT ++D++ DVT AN MESSG G
Sbjct: 2523 MIQIINDIKQDPQYQHLNMRIGVHTGRVLGGVVGTDVVRYDIYGEDVTIANLMESSGTEG 2582
Query: 432 RVHISEETSQFLGGSY 447
++ IS+ T + Y
Sbjct: 2583 KMLISDYTKNLVESEY 2598
Score = 41.5 bits (93), Expect = 0.075
Identities = 15/66 (22%), Positives = 39/66 (59%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M++A++ + + +++G+H G V+ G++G + +F + + V +++ S+G G
Sbjct: 1732 AMMDAVKTMKYGDNQDVKLKIGIHYGRVIAGVIGVHKPQFSLIGDTVNTTSRVCSTGDAG 1791
Query: 432 RVHISE 437
+ +SE
Sbjct: 1792 FITLSE 1797
>UniRef50_UPI00006CEB6E Cluster: Adenylate and Guanylate cyclase
catalytic domain containing protein; n=1; Tetrahymena
thermophila SB210|Rep: Adenylate and Guanylate cyclase
catalytic domain containing protein - Tetrahymena
thermophila SB210
Length = 2842
Score = 68.9 bits (161), Expect = 4e-10
Identities = 29/61 (47%), Positives = 45/61 (73%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGG 445
E ++MR+GVHTG ++ G++GT ++DV+ +DVT ANKMES+G+ G++ IS+ T L
Sbjct: 2737 EELDMRIGVHTGRIIGGVIGTDIVRYDVYGSDVTIANKMESNGERGKILISQVTYDLLAN 2796
Query: 446 S 446
S
Sbjct: 2797 S 2797
Score = 41.1 bits (92), Expect = 0.099
Identities = 15/69 (21%), Positives = 43/69 (62%), Gaps = 1/69 (1%)
Query: 384 RGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+G+ + +++G+H G V+ G++G + +F + + V +++ S+G+ G++ +S++ +
Sbjct: 1966 QGQSMVIKIGIHYGKVMAGVIGYHKPQFSLIGDTVNTTSRVMSTGENGKITLSKQAFDQI 2025
Query: 444 GGSYILEEG 452
++ E+G
Sbjct: 2026 -NQFLQEQG 2033
>UniRef50_Q89SW2 Cluster: Two-component hybrid sensor and regulator;
n=3; Bacteria|Rep: Two-component hybrid sensor and
regulator - Bradyrhizobium japonicum
Length = 527
Score = 68.9 bits (161), Expect = 4e-10
Identities = 29/88 (32%), Positives = 53/88 (60%), Gaps = 1/88 (1%)
Query: 364 IVGFTRMS-SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFAN 422
I +M+ MI+ + + G + +R+G+H+G V+ GI+G RF +DVW + V A+
Sbjct: 419 IAAIAKMALGMIDRLGRVNSHFGWPLQIRIGIHSGPVVAGIIGAHRFIYDVWGDTVNVAS 478
Query: 423 KMESSGKPGRVHISEETSQFLGGSYILE 450
++E+ P R+H+S + ++ L G + LE
Sbjct: 479 RLEAYSLPNRIHVSRDIARHLVGRFALE 506
>UniRef50_A0YPF4 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC
8106|Rep: Adenylate cyclase - Lyngbya sp. PCC 8106
Length = 491
Score = 68.9 bits (161), Expect = 4e-10
Identities = 31/101 (30%), Positives = 65/101 (64%), Gaps = 5/101 (4%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M++ + +F+ + + +R+G+++G V+ GI+GT++F +D+W + V A++MES G G
Sbjct: 384 MLDDLNQFNAKNNVKLEIRIGINSGPVIAGIIGTKKFIYDLWGDAVNTASRMESHGIAGE 443
Query: 433 VHISEETSQFLGGSYI-LEEG-EEVFGH---KTYFIEGRQV 468
+ ++E T +L ++ +E G E+ G +TY ++GR++
Sbjct: 444 IQLTETTFDYLQKEFLFVERGLIEIKGKGKMRTYLLKGRRL 484
>UniRef50_Q24GP9 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Adenylate and Guanylate cyclase catalytic
domain containing protein - Tetrahymena thermophila SB210
Length = 3203
Score = 68.9 bits (161), Expect = 4e-10
Identities = 30/73 (41%), Positives = 49/73 (67%), Gaps = 1/73 (1%)
Query: 372 SMIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
SM++ IQ+ +E +G+NMR+G+H G ++ G++GT ++DV+ V ANKMES+
Sbjct: 3095 SMVKIIQKVKKEINFDGLNMRIGLHIGDIIGGVIGTDIVRYDVYGKSVVIANKMESNSTT 3154
Query: 431 GRVHISEETSQFL 443
GR+ ISE+ + L
Sbjct: 3155 GRIRISEDYKKIL 3167
>UniRef50_Q98GN7 Cluster: Cyclase; n=1; Mesorhizobium loti|Rep:
Cyclase - Rhizobium loti (Mesorhizobium loti)
Length = 356
Score = 68.5 bits (160), Expect = 6e-10
Identities = 26/73 (35%), Positives = 48/73 (65%), Gaps = 1/73 (1%)
Query: 375 EAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVH 434
EA+Q +R GE + +R+G+H+G ++ G++G RRF +D+W V A ++++S +P +
Sbjct: 262 EAVQH-ERFAGERLRLRIGIHSGPIVAGVIGKRRFAYDLWGETVNLAARIQTSAEPDEIR 320
Query: 435 ISEETSQFLGGSY 447
IS+ T + LG +
Sbjct: 321 ISDATRRLLGPDF 333
>UniRef50_Q9EXQ2 Cluster: Adenylate cyclase; n=3;
Oscillatoriales|Rep: Adenylate cyclase - Spirulina
platensis
Length = 671
Score = 68.5 bits (160), Expect = 6e-10
Identities = 26/66 (39%), Positives = 46/66 (69%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGG 445
E +R+G++TG V+ G++G ++F +D+W + V A++MESSG PG + ++EET L
Sbjct: 579 ESFQIRIGINTGAVVAGVIGIKKFIYDLWGDAVNIASRMESSGTPGSIQVTEETYHRLKY 638
Query: 446 SYILEE 451
+YI ++
Sbjct: 639 NYIFKK 644
>UniRef50_Q1H0Z8 Cluster: Adenylate/guanylate cyclase; n=1;
Methylobacillus flagellatus KT|Rep: Adenylate/guanylate
cyclase - Methylobacillus flagellatus (strain KT / ATCC
51484 / DSM 6875)
Length = 426
Score = 68.5 bits (160), Expect = 6e-10
Identities = 33/95 (34%), Positives = 55/95 (57%), Gaps = 5/95 (5%)
Query: 377 IQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHIS 436
+ + RE G + MR+G+++G V+ GI+G RF +D+W + V A++ME++G P + +S
Sbjct: 322 LDKVSREIGMPLAMRIGMNSGAVVAGIIGNTRFSYDLWGDAVNIASRMETTGLPNEIQVS 381
Query: 437 EETSQFLGGSYILEE--GEEVFGH---KTYFIEGR 466
T + L Y E G +V G TY ++GR
Sbjct: 382 AATYELLKADYCFEPRCGVDVKGKGKVVTYLLKGR 416
>UniRef50_Q231I7 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=2; Tetrahymena|Rep:
Adenylate and Guanylate cyclase catalytic domain
containing protein - Tetrahymena thermophila SB210
Length = 2997
Score = 68.5 bits (160), Expect = 6e-10
Identities = 31/74 (41%), Positives = 47/74 (63%), Gaps = 5/74 (6%)
Query: 374 IEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRV 433
+ A+ FD + MR+G+HTG+++ G+VGT ++D++ DV ANKMES+G+ GRV
Sbjct: 2878 VRAVVNFDE-----LEMRIGIHTGSIIGGVVGTGVVRYDIYGPDVVIANKMESNGESGRV 2932
Query: 434 HISEETSQFLGGSY 447
ISE T + Y
Sbjct: 2933 MISEATYNLVNDGY 2946
Score = 40.7 bits (91), Expect = 0.13
Identities = 20/77 (25%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Query: 384 RGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET-SQF 442
+ + +N+++G+H G V+ G++G + +F + + V A+++ S+G V IS E +Q
Sbjct: 2298 KSDKLNVKIGIHYGRVMAGVIGGHKPQFSLIGDTVNMASRVCSTGAADSVTISAEARAQC 2357
Query: 443 LGGSYILEEGEEVFGHK 459
L + ++ F K
Sbjct: 2358 FKQIEFLNKNQQYFNLK 2374
>UniRef50_A0D3H6 Cluster: Chromosome undetermined scaffold_36, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_36, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2471
Score = 68.1 bits (159), Expect = 8e-10
Identities = 32/77 (41%), Positives = 50/77 (64%), Gaps = 1/77 (1%)
Query: 372 SMIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
+M+EAI + ++MR+G+HTG V+ GI+GT ++DV+ D+ ANKMESS +
Sbjct: 2365 NMLEAISLVRNQINYHDLHMRIGIHTGNVIGGIIGTDIIRYDVYGKDILIANKMESSSEE 2424
Query: 431 GRVHISEETSQFLGGSY 447
GRV ISE T + + ++
Sbjct: 2425 GRVLISETTKKLIEDNF 2441
>UniRef50_A0CEN0 Cluster: Chromosome undetermined scaffold_172, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_172, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2514
Score = 68.1 bits (159), Expect = 8e-10
Identities = 31/83 (37%), Positives = 53/83 (63%), Gaps = 3/83 (3%)
Query: 365 VGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKM 424
+GF M S+I+ ++ D +G++MR+G+HTG ++ G++GT ++D++ DV ANKM
Sbjct: 2388 LGF-EMISIIKRVR--DHINFQGLDMRIGIHTGNIIGGVLGTEIVRYDIYGPDVLIANKM 2444
Query: 425 ESSGKPGRVHISEETSQFLGGSY 447
ES G+ G + +S T + L Y
Sbjct: 2445 ESKGERGNLQVSSTTKEILEQHY 2467
Score = 45.2 bits (102), Expect = 0.006
Identities = 20/63 (31%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Query: 385 GEG-INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
G G I +++GVH G V+ G++G + +F + + V +++ S+G+ G++ ISE+ + +
Sbjct: 1835 GSGEIIVKIGVHYGNVIAGVIGYHKPQFSLIGDTVNTTSRVCSTGQDGQIKISEDAYKLV 1894
Query: 444 GGS 446
GS
Sbjct: 1895 SGS 1897
>UniRef50_Q9XTY1 Cluster: Guanylate cyclase; n=2;
Caenorhabditis|Rep: Guanylate cyclase - Caenorhabditis
elegans
Length = 1012
Score = 67.7 bits (158), Expect = 1e-09
Identities = 39/89 (43%), Positives = 56/89 (62%), Gaps = 5/89 (5%)
Query: 372 SMIEAIQEFDRER--GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
S+++AI+ F E IN+RVG+HTG V+ G+VG ++ ++ + V A++MES+GK
Sbjct: 896 SLLKAIKTFRVPHLPKERINIRVGLHTGPVVTGVVGMTMPRYCLFGDSVNTASRMESNGK 955
Query: 430 PGRVHISEETSQFLG---GSYILEEGEEV 455
PGRVHIS E +FL G Y E EV
Sbjct: 956 PGRVHISTECMKFLTEVIGGYQTEPRGEV 984
>UniRef50_Q16JH8 Cluster: Soluble guanylate cyclase gcy; n=2;
Culicidae|Rep: Soluble guanylate cyclase gcy - Aedes
aegypti (Yellowfever mosquito)
Length = 1025
Score = 67.7 bits (158), Expect = 1e-09
Identities = 38/101 (37%), Positives = 64/101 (63%), Gaps = 6/101 (5%)
Query: 373 MIEAIQEF-DRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
MIEAI + D G + +RVGVH+G V+ GIVG + ++ ++ + V A++MES+ +
Sbjct: 499 MIEAITDLKDPSTGSHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDSVNTASRMESTSQAM 558
Query: 432 RVHISEETSQFLGGSY-ILEEGE-EVFGH---KTYFIEGRQ 467
++HIS+ T FL +Y + E GE +V G KTY+++ ++
Sbjct: 559 KIHISQSTRNFLPSNYHVSERGEIDVKGKGTMKTYWLDHKE 599
>UniRef50_A7AX98 Cluster: Adenylate and guanylate cyclase catalytic
domain containing protein; n=1; Babesia bovis|Rep:
Adenylate and guanylate cyclase catalytic domain
containing protein - Babesia bovis
Length = 2446
Score = 67.7 bits (158), Expect = 1e-09
Identities = 35/85 (41%), Positives = 55/85 (64%), Gaps = 4/85 (4%)
Query: 362 ADIVGFTRMS-SMIEAIQEFDRERGE--GINMRVGVHTGTVLCGIVGTRRFKFDVWSNDV 418
A+I G +M+ SMI I++ RE + G+NMR+G+H G + G++G+ R ++D+W D+
Sbjct: 2325 ANIDGILQMAQSMIRTIRDV-RESFDIPGLNMRIGLHYGHAVGGVIGSGRLRYDLWGMDI 2383
Query: 419 TFANKMESSGKPGRVHISEETSQFL 443
AN MES G PG+++ISE L
Sbjct: 2384 HTANAMESHGIPGKINISERLKLIL 2408
Score = 50.0 bits (114), Expect = 2e-04
Identities = 25/113 (22%), Positives = 62/113 (54%), Gaps = 5/113 (4%)
Query: 356 NVSILFADIVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWS 415
++++ ++ R +SM E E+ + ++VG+++G ++ G+VG ++ ++ ++
Sbjct: 1671 DMALAMIEVARSIRYTSMQERDDGTFAEQDDVAVVKVGINSGKIISGLVGFKKPQYALFG 1730
Query: 416 NDVTFANKMESSGKPGRVHISEETSQFLGGSYILEEGEEVFGHKTYFIEGRQV 468
+ V A++M+++G+ G +HIS T + L F H+ F++G+ +
Sbjct: 1731 DTVNTASRMKTTGESGYIHISTSTYDLVKSDVTLH-----FEHRETFVKGKGI 1778
>UniRef50_A0BPN4 Cluster: Chromosome undetermined scaffold_12, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_12, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2459
Score = 67.7 bits (158), Expect = 1e-09
Identities = 30/72 (41%), Positives = 48/72 (66%), Gaps = 1/72 (1%)
Query: 373 MIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
M+E I++ RE + +NMR+G+HTG GI+GT ++D++ D ANKMES G+ G
Sbjct: 2343 MVEIIKKVRREINFQNLNMRIGIHTGQFYGGIIGTDIVRYDIFGIDAVIANKMESQGEAG 2402
Query: 432 RVHISEETSQFL 443
+V +SE+T + +
Sbjct: 2403 KVMVSEDTRRLI 2414
Score = 44.0 bits (99), Expect = 0.014
Identities = 20/68 (29%), Positives = 39/68 (57%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSY 447
+ +++G+H G V G++G + +F + + V A++M S+G+ GR+ IS E + + +
Sbjct: 1760 LKIKIGIHYGQVFAGVIGYHKPQFSLIGDTVNTASRMCSTGEVGRITISSEAYERVKDTE 1819
Query: 448 ILEEGEEV 455
L EV
Sbjct: 1820 FLFTSREV 1827
>UniRef50_Q8INF0 Cluster: Soluble guanylate cyclase 88E; n=12;
Coelomata|Rep: Soluble guanylate cyclase 88E -
Drosophila melanogaster (Fruit fly)
Length = 947
Score = 67.7 bits (158), Expect = 1e-09
Identities = 44/120 (36%), Positives = 70/120 (58%), Gaps = 8/120 (6%)
Query: 373 MIEAIQEF-DRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
M++AI + D G+ + +RVGVH+G V+ GIVG + ++ ++ + V A++MES+
Sbjct: 496 MVDAITDLKDPSTGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAM 555
Query: 432 RVHISEETSQFLGGSY-ILEEGE-EVFGH---KTYFIEGRQVFCPYDREQCLT--PSNPV 484
+VHISE T +G +Y I+E GE +V G TY++E R+ P L P +PV
Sbjct: 556 KVHISESTKVLIGPNYKIIERGEIDVKGKGTMGTYWLEERENRLPLQLTAALQVHPLSPV 615
>UniRef50_UPI00006CF863 Cluster: Adenylate and Guanylate cyclase
catalytic domain containing protein; n=1; Tetrahymena
thermophila SB210|Rep: Adenylate and Guanylate cyclase
catalytic domain containing protein - Tetrahymena
thermophila SB210
Length = 1213
Score = 67.3 bits (157), Expect = 1e-09
Identities = 31/75 (41%), Positives = 48/75 (64%), Gaps = 4/75 (5%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL-- 443
E + MR+GVHTG+ + G++GT ++D++ DV ANKMES+G+ G+V +S+ T L
Sbjct: 1121 EELEMRIGVHTGSYIGGVIGTDIVRYDIYGPDVMIANKMESNGEQGKVMVSKTTMNLLYD 1180
Query: 444 --GGSYILEEGEEVF 456
G Y +G EV+
Sbjct: 1181 HYGSRYNFTKGNEVY 1195
Score = 47.6 bits (108), Expect = 0.001
Identities = 18/66 (27%), Positives = 43/66 (65%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M++ I++F+ E + +++G+H G V+ G++G + +F + + V A+++ S+G G+
Sbjct: 324 MMDIIKQFNYGDNEKVKIKIGIHYGRVIAGVIGCHKPQFSLIGDTVNTASRVCSTGDVGQ 383
Query: 433 VHISEE 438
+ +SE+
Sbjct: 384 ITLSEQ 389
>UniRef50_UPI00006CB402 Cluster: Adenylate and Guanylate cyclase
catalytic domain containing protein; n=1; Tetrahymena
thermophila SB210|Rep: Adenylate and Guanylate cyclase
catalytic domain containing protein - Tetrahymena
thermophila SB210
Length = 2703
Score = 67.3 bits (157), Expect = 1e-09
Identities = 35/88 (39%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MIE ++ I+MR+GVHTG ++ G+VGT+ ++D++ DV ANKMES+G+ G
Sbjct: 2598 MIEILKRTTELVENQIDMRIGVHTGKIVGGLVGTQIVRYDIYGVDVMIANKMESNGQKGS 2657
Query: 433 VHISEETSQFL----GGSYILEEGEEVF 456
V +SE T L G +I E +V+
Sbjct: 2658 VVVSETTKDILQERYGKEFIFTEKGDVY 2685
Score = 39.1 bits (87), Expect = 0.40
Identities = 15/54 (27%), Positives = 35/54 (64%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQ 441
+ +++G++ GTV+ G++G + +F + + V A+++ S+G P ++IS + Q
Sbjct: 1953 VEIKIGINYGTVISGVIGFHKPQFSLIGDTVNTASRVCSTGLPKTINISNSSYQ 2006
>UniRef50_Q9U928 Cluster: Guanylyl cyclase; n=2; Tetrahymena
pyriformis|Rep: Guanylyl cyclase - Tetrahymena pyriformis
Length = 2794
Score = 67.3 bits (157), Expect = 1e-09
Identities = 31/75 (41%), Positives = 48/75 (64%), Gaps = 4/75 (5%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL-- 443
E + MR+GVHTG+ + G++GT ++D++ DV ANKMES+G+ G+V +S+ T L
Sbjct: 2702 EELEMRIGVHTGSYIGGVIGTDIVRYDIYGPDVMVANKMESNGEQGKVMVSKTTMNLLLE 2761
Query: 444 --GGSYILEEGEEVF 456
G Y +G +VF
Sbjct: 2762 NYGNRYNFNKGNDVF 2776
Score = 50.4 bits (115), Expect = 2e-04
Identities = 22/66 (33%), Positives = 42/66 (63%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+EA++ F E I +++G+H G V+ G++G + +F + + V A+++ S+G G+
Sbjct: 1838 MMEAMKSFTYGDNEKIKIKIGIHYGRVIAGVIGCHKPQFSLIGDTVNMASRVCSTGDVGQ 1897
Query: 433 VHISEE 438
V IS+E
Sbjct: 1898 VTISDE 1903
>UniRef50_UPI00006CFA91 Cluster: Adenylate and Guanylate cyclase
catalytic domain containing protein; n=1; Tetrahymena
thermophila SB210|Rep: Adenylate and Guanylate cyclase
catalytic domain containing protein - Tetrahymena
thermophila SB210
Length = 2815
Score = 66.9 bits (156), Expect = 2e-09
Identities = 31/75 (41%), Positives = 46/75 (61%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI I+ + + MR+GVHTG + GIVGT ++D++ DV ANKMES+G+ G
Sbjct: 2717 MIRIIENVRQYTDCNLQMRIGVHTGKLYGGIVGTEIVRYDIYGQDVIIANKMESNGESGH 2776
Query: 433 VHISEETSQFLGGSY 447
V +SE T + L ++
Sbjct: 2777 VMVSETTKKLLEDNF 2791
>UniRef50_Q5UFR4 Cluster: Cya1625; n=1; Mycobacterium smegmatis|Rep:
Cya1625 - Mycobacterium smegmatis
Length = 369
Score = 66.9 bits (156), Expect = 2e-09
Identities = 35/100 (35%), Positives = 60/100 (60%), Gaps = 5/100 (5%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M A+ + G + +R+G+ G V+ G+VG RRF +DVW + V A++MES+ GR
Sbjct: 247 MAAAVADLTDPEGRRVPLRIGLAAGPVVAGVVGARRFFYDVWGDAVNVASRMESTDVEGR 306
Query: 433 VHISEETSQFLGGSYILEE-GE-EVFGH---KTYFIEGRQ 467
+ + ++ L +++LEE GE EV G +T+++ GR+
Sbjct: 307 IQVPDDMCLRLRHAFVLEERGEVEVKGKGVMRTWYLVGRR 346
>UniRef50_Q1NSQ3 Cluster: Adenylate cyclase; n=1; delta
proteobacterium MLMS-1|Rep: Adenylate cyclase - delta
proteobacterium MLMS-1
Length = 480
Score = 66.9 bits (156), Expect = 2e-09
Identities = 33/92 (35%), Positives = 57/92 (61%), Gaps = 5/92 (5%)
Query: 369 RMSSM-IEAIQEFDRERGE----GINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANK 423
R++ M +E ++EFDR + E ++RVG+ TG V+ G++G+ +F +D+W + V AN+
Sbjct: 361 RVADMALELMREFDRLKQELQVTDFSIRVGIATGPVVSGVIGSVKFAYDLWGDTVNAANR 420
Query: 424 MESSGKPGRVHISEETSQFLGGSYILEEGEEV 455
+ESS PGR+H + + L Y E+ E+
Sbjct: 421 LESSALPGRIHCNARFAHRLQEHYRFEDRGEI 452
>UniRef50_A0YN57 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC
8106|Rep: Adenylate cyclase - Lyngbya sp. PCC 8106
Length = 545
Score = 66.9 bits (156), Expect = 2e-09
Identities = 69/271 (25%), Positives = 128/271 (47%), Gaps = 40/271 (14%)
Query: 230 VLNIVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQL 289
+ N ++ LS +E Q + +R Q I+ + M V + + QS L +QL
Sbjct: 278 ISNQLISLSNEEIQFAHQEIRRTSQQMTVILLSSVIAM--VTLSVVIWRSFQSAL--KQL 333
Query: 290 EMEKQLKEKMIHSVMPPKLASNLMN---------EQVTEADTNVKTYHNPLNSRIS---- 336
E+E++ E+++ +++P +A L N E+VT ++ + L+++IS
Sbjct: 334 EVEQEKSERLLLNILPESIALRLKNKPETIADNFEEVTVLFADIAGF-TQLSAKISPTEL 392
Query: 337 -NPGSDIKSLFRPF----NMSCMDNVSILFADIVGFTR-MSSMIEAIQ-----------E 379
N ++I S F N+ + + + + G S EAI E
Sbjct: 393 VNLLNEIFSEFDQITTQNNLEKIKTIGDAYLVVGGLPNPRSDHAEAIAKLALEMQNKLIE 452
Query: 380 FDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
F+++ + +R+G++TG V+ G++G ++F +D+W + V A++MES G G + ++E T
Sbjct: 453 FNQKHDHNLQLRIGINTGPVVAGVIGAKKFIYDLWGDTVNIASRMESHGIIGEIQVTEAT 512
Query: 440 SQFLGGSYILEEGE--EVFGH---KTYFIEG 465
Q L Y E+ V G TYF++G
Sbjct: 513 YQRLQDKYKFEKRGLINVKGKGEMSTYFLKG 543
>UniRef50_Q9XZS0 Cluster: Guanylyl cyclase; n=4; cellular
organisms|Rep: Guanylyl cyclase - Dictyostelium
discoideum (Slime mold)
Length = 1486
Score = 66.9 bits (156), Expect = 2e-09
Identities = 27/79 (34%), Positives = 44/79 (55%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+E+I+ I MR+G+HTG V+ G+VG + + +W V +MES+ +
Sbjct: 1247 MLESIKSIRTVDNIPIRMRIGIHTGPVIAGVVGIKMIHYQLWGESVQITQQMESTSRADM 1306
Query: 433 VHISEETSQFLGGSYILEE 451
+H+SE+T L Y+ EE
Sbjct: 1307 IHVSEDTFNILKSKYLFEE 1325
Score = 47.2 bits (107), Expect = 0.002
Identities = 17/64 (26%), Positives = 38/64 (59%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSY 447
+ +R+G+HTG V+ GI+G ++ + ++ + + +++M S GR+ +S Q L +
Sbjct: 480 VQVRIGMHTGPVVGGIIGKKKLSWHLFGDTINTSSRMASHSSIGRIQVSHPVQQLLRPYF 539
Query: 448 ILEE 451
+ E+
Sbjct: 540 LFED 543
>UniRef50_UPI000038D385 Cluster: COG2114: Adenylate cyclase, family
3 (some proteins contain HAMP domain); n=1; Nostoc
punctiforme PCC 73102|Rep: COG2114: Adenylate cyclase,
family 3 (some proteins contain HAMP domain) - Nostoc
punctiforme PCC 73102
Length = 433
Score = 66.5 bits (155), Expect = 2e-09
Identities = 27/79 (34%), Positives = 48/79 (60%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M AI F+ E + ++R+G+ TG V+ G++G ++F +D+W + V A++MES G G
Sbjct: 331 MQNAIAIFNAENNQLFSIRIGISTGPVVAGVIGLKKFAYDLWGDTVNTASRMESHGIAGN 390
Query: 433 VHISEETSQFLGGSYILEE 451
+ + E T Q L Y+ ++
Sbjct: 391 IQVCEATYQLLKDKYLFDK 409
>UniRef50_Q1NWK5 Cluster: Guanylate cyclase; n=2; delta
proteobacterium MLMS-1|Rep: Guanylate cyclase - delta
proteobacterium MLMS-1
Length = 323
Score = 66.5 bits (155), Expect = 2e-09
Identities = 32/83 (38%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
Query: 378 QEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISE 437
Q F + R+G+H+G V G+VG R +FDV+ + V A + E++G+PGRV+IS
Sbjct: 221 QRFGAATAQYFRCRIGIHSGPVTAGVVGEDRMQFDVFGDHVNIAARFETAGEPGRVNISA 280
Query: 438 ETSQFLGGSYILEE-GEEVFGHK 459
T Q L + + E+ GE HK
Sbjct: 281 ATRQHLPPNLVCEDRGEVALKHK 303
>UniRef50_A7C2F8 Cluster: Rh-like protein/ammonium transporter; n=1;
Beggiatoa sp. PS|Rep: Rh-like protein/ammonium
transporter - Beggiatoa sp. PS
Length = 391
Score = 66.1 bits (154), Expect = 3e-09
Identities = 27/66 (40%), Positives = 43/66 (65%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLG 444
G+ + MR+G+H+G V+ G++G R+F +D+W + V A++MES G PG ++E T L
Sbjct: 296 GKPLQMRIGLHSGPVIAGVIGKRKFIYDLWGDTVNTASRMESHGIPGETQVTEGTYLRLK 355
Query: 445 GSYILE 450
YI E
Sbjct: 356 TDYIFE 361
>UniRef50_A5K544 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Plasmodium vivax|Rep:
Adenylate and Guanylate cyclase catalytic domain
containing protein - Plasmodium vivax
Length = 3979
Score = 66.1 bits (154), Expect = 3e-09
Identities = 31/74 (41%), Positives = 49/74 (66%), Gaps = 3/74 (4%)
Query: 372 SMIEAIQEFDRERG--EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
SMI I+E RE+ +NMR+G+H G+ + G++G+ R ++D+W DV N MES+G
Sbjct: 3801 SMIRIIKEI-REKLCIPNLNMRIGLHYGSCVGGVIGSGRLRYDLWGIDVLTGNLMESNGV 3859
Query: 430 PGRVHISEETSQFL 443
PG++++SE FL
Sbjct: 3860 PGKINVSETLKNFL 3873
Score = 50.4 bits (115), Expect = 2e-04
Identities = 17/52 (32%), Positives = 40/52 (76%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
I +++G+++G ++ G+VG+++ ++ ++ + V A++M+++GKP +HISE T
Sbjct: 2990 IRVKIGINSGRIIAGVVGSKKPQYALFGDTVNTASRMKTTGKPDYIHISEAT 3041
>UniRef50_A0C5P9 Cluster: Chromosome undetermined scaffold_150, whole
genome shotgun sequence; n=5; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_150, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2413
Score = 66.1 bits (154), Expect = 3e-09
Identities = 32/83 (38%), Positives = 51/83 (61%), Gaps = 2/83 (2%)
Query: 363 DIVGFTRMS-SMIEAIQEFDRERGEG-INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTF 420
+ V RM +MI+AI+ ++MR+GVHTG+++ G++GT ++D++ DV
Sbjct: 2299 EAVNVVRMGFAMIDAIRRVRAHINHPTLDMRIGVHTGSIIGGVLGTELVRYDIYGPDVLI 2358
Query: 421 ANKMESSGKPGRVHISEETSQFL 443
ANKMES G G V +S+ET +
Sbjct: 2359 ANKMESKGAKGFVQVSQETKDII 2381
Score = 40.3 bits (90), Expect = 0.17
Identities = 48/245 (19%), Positives = 113/245 (46%), Gaps = 36/245 (14%)
Query: 223 IYSIVFEVLNIVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQS 282
+ S VF + ++++L ++ +++ ++ Q + I + + ++TF R+ F++V
Sbjct: 1536 LISQVFSAIYVIIYLIKKS-DEDDVYI-LINQYVMSIASLFLLVVTFRRIIHIFLEV--- 1590
Query: 283 LLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNE-----------QVTEADTNVKTYHNPL 331
L R + E Q+ ++ S++ P+ + +N+ V ++ + +
Sbjct: 1591 FLGRINMNKENQIMSDIL-SILLPQFIRDRINKAGQYDIQEDQGMVAVLFCDIIDFDQLI 1649
Query: 332 NSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSSM---IEAIQE--------- 379
+ SN + LFR F++ C + + + VG T M++ I Q+
Sbjct: 1650 KNEQSNVVDILDKLFRRFDLLCQQH-EVQKIETVGKTYMAAAGLKIHMSQKSNPVNKVIS 1708
Query: 380 --FDRER----GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRV 433
D +R E +++G+H G V+ G++G + +F + + + A+++ S+ +P +
Sbjct: 1709 LALDMKRHVMSNEVFQIKIGIHYGNVIAGVIGHHKPQFSLIGDTINTASRICSTAEPWDI 1768
Query: 434 HISEE 438
ISE+
Sbjct: 1769 AISEQ 1773
>UniRef50_Q92WJ5 Cluster: Putative regulatory protein; n=2;
Sinorhizobium|Rep: Putative regulatory protein -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 520
Score = 65.7 bits (153), Expect = 4e-09
Identities = 32/80 (40%), Positives = 49/80 (61%), Gaps = 3/80 (3%)
Query: 372 SMIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
SM+ ++Q D E G + +R+G+HTG V+ G++G RF +DVW V A+++ES G
Sbjct: 424 SMLRSLQ--DMEAGPDRFRVRIGIHTGPVVAGLIGRLRFVYDVWGETVNIASRLESQGVA 481
Query: 431 GRVHISEETSQFLGGSYILE 450
+ ISE T + L G + LE
Sbjct: 482 DVIQISEATRRALRGPWTLE 501
>UniRef50_A1ZVN3 Cluster: Adenylate or guanylate cyclase; n=1;
Microscilla marina ATCC 23134|Rep: Adenylate or
guanylate cyclase - Microscilla marina ATCC 23134
Length = 774
Score = 65.7 bits (153), Expect = 4e-09
Identities = 27/54 (50%), Positives = 38/54 (70%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+R+G+HTG V+ G+VG +F +DVW + V A +MESSG PG V+IS T Q +
Sbjct: 692 LRLGIHTGEVVAGVVGKNKFAYDVWGDTVNLAARMESSGAPGMVNISGHTYQLI 745
>UniRef50_Q9N9H5 Cluster: Guanylyl cyclase; n=3; Plasmodium
falciparum|Rep: Guanylyl cyclase - Plasmodium falciparum
Length = 4226
Score = 65.7 bits (153), Expect = 4e-09
Identities = 31/74 (41%), Positives = 49/74 (66%), Gaps = 3/74 (4%)
Query: 372 SMIEAIQEFDRERG--EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
SMI I+E RE+ +NMR+G+H G+ + G++G+ R ++D+W DV N MES+G
Sbjct: 4050 SMIRIIKEI-REKLYIPNLNMRIGLHYGSCVGGVIGSGRLRYDLWGIDVLTGNLMESNGI 4108
Query: 430 PGRVHISEETSQFL 443
PG++++SE FL
Sbjct: 4109 PGKINVSETLKNFL 4122
Score = 54.8 bits (126), Expect = 8e-06
Identities = 20/59 (33%), Positives = 42/59 (71%)
Query: 381 DRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
D + I ++VG+H+G ++ G+VG+++ ++ ++ + V A++M+++GKP +HISE T
Sbjct: 3226 DNNKPTRIRVKVGIHSGRIIAGVVGSKKPQYALFGDTVNTASRMKTTGKPDYIHISEAT 3284
>UniRef50_P0A4Y1 Cluster: Adenylate cyclase; n=15;
Mycobacterium|Rep: Adenylate cyclase - Mycobacterium
bovis
Length = 443
Score = 65.7 bits (153), Expect = 4e-09
Identities = 34/90 (37%), Positives = 57/90 (63%), Gaps = 5/90 (5%)
Query: 384 RGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
RG + +RVG+ TG V+ G+VG+RRF +DVW + V A++MES+ G++ + +E + L
Sbjct: 337 RGNPVPLRVGLATGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGQIQVPDEVYERL 396
Query: 444 GGSYIL-EEGE-EVFGH---KTYFIEGRQV 468
++L E G V G +T+++ GR+V
Sbjct: 397 KDDFVLRERGHINVKGKGVMRTWYLIGRKV 426
>UniRef50_Q7YXG1 Cluster: Soluble guanylyl cyclase 2 beta; n=1;
Limax marginatus|Rep: Soluble guanylyl cyclase 2 beta -
Limax marginatus
Length = 406
Score = 65.3 bits (152), Expect = 5e-09
Identities = 36/89 (40%), Positives = 54/89 (60%), Gaps = 6/89 (6%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL- 443
G+ + +RVG+HTG V+ G+VG R ++ ++ + V A++MES G PGR+H+S T Q L
Sbjct: 150 GKPLQIRVGIHTGPVVAGVVGVRMPRYCLFGDTVNTASRMESHGMPGRIHLSPSTFQALE 209
Query: 444 GGSYILE-EGEEVFGHK----TYFIEGRQ 467
G Y + GE + K TYF+ G Q
Sbjct: 210 GQGYTCKCRGETLIKGKGCMVTYFLLGDQ 238
Score = 39.9 bits (89), Expect = 0.23
Identities = 16/35 (45%), Positives = 26/35 (74%)
Query: 287 RQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEAD 321
R+LEMEKQ E++++ ++P K+A+ L N Q EA+
Sbjct: 22 RELEMEKQKTERLLYQMLPEKVANQLKNGQAVEAE 56
>UniRef50_Q16W55 Cluster: Adenylate cyclase; n=1; Aedes aegypti|Rep:
Adenylate cyclase - Aedes aegypti (Yellowfever mosquito)
Length = 554
Score = 65.3 bits (152), Expect = 5e-09
Identities = 29/95 (30%), Positives = 56/95 (58%), Gaps = 1/95 (1%)
Query: 350 NMSCMDNVSILFADIVGFTRMS-SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRR 408
N S +D +S+ +A + + + +A+Q + + +++GV+ G + G++G R+
Sbjct: 427 NPSRIDPISVRWAHLALLVEFALELKKALQGINEQSFNHFVLKMGVNHGPITAGVIGARK 486
Query: 409 FKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+D+W N V A++MES+GK G + ++EET Q L
Sbjct: 487 PHYDIWGNTVNVASRMESTGKAGAIQVTEETCQIL 521
>UniRef50_Q4SU92 Cluster: Chromosome 3 SCAF13974, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF13974, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1108
Score = 64.5 bits (150), Expect = 9e-09
Identities = 23/44 (52%), Positives = 38/44 (86%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
++MR+GVH+G+VLCG++G ++++FD+WS DV AN +E++G PG
Sbjct: 398 LDMRIGVHSGSVLCGVLGLQKWQFDIWSWDVDIANSLEAAGVPG 441
Score = 48.8 bits (111), Expect = 5e-04
Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
Query: 393 GVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETS----------QF 442
GV G V+ G++G + ++D+W V A++MES+G G + + E TS Q
Sbjct: 974 GVAHGPVIAGVIGATKPQYDIWGTTVNLASRMESTGISGMIQVPEATSCILVERGFLRQL 1033
Query: 443 LGGSYILEEGEEVFGHKTYFIEGRQVFCPYDREQC 477
G YI E +T+F+ R+ + C
Sbjct: 1034 RGSIYIKGISERHGKIRTFFVSSREERASFTERGC 1068
>UniRef50_Q23DS0 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Adenylate and Guanylate cyclase catalytic
domain containing protein - Tetrahymena thermophila SB210
Length = 3179
Score = 64.1 bits (149), Expect = 1e-08
Identities = 29/78 (37%), Positives = 51/78 (65%), Gaps = 6/78 (7%)
Query: 372 SMIEAIQEFDRERGE------GINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKME 425
SMIE++++F E+ + I+MR+G+H G ++ G++G ++D++ DV ANKME
Sbjct: 3065 SMIESLRQFRLEQKDPSDQNADIHMRIGIHIGDIIGGVIGKNVVRYDIYGKDVLLANKME 3124
Query: 426 SSGKPGRVHISEETSQFL 443
S+G+ GR+ IS+ Q +
Sbjct: 3125 SNGERGRILISDPLKQVI 3142
Score = 36.3 bits (80), Expect = 2.8
Identities = 14/53 (26%), Positives = 31/53 (58%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISE 437
G + +++GVH G + G++G + +F + + V +++ S+ +PGR S+
Sbjct: 2326 GYPVKLKIGVHIGPITAGVIGYHKPQFSLIGDTVNTTSRLCSNCEPGRSLFSD 2378
>UniRef50_A1ZFP4 Cluster: Two-component hybrid sensor and regulator;
n=1; Microscilla marina ATCC 23134|Rep: Two-component
hybrid sensor and regulator - Microscilla marina ATCC
23134
Length = 1269
Score = 63.7 bits (148), Expect = 2e-08
Identities = 27/67 (40%), Positives = 45/67 (67%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYI 448
++R+GV+TG V+ G++GT++F +DVW + V A +MES GK G V+IS T + + +
Sbjct: 1164 DVRLGVNTGEVIAGVIGTKKFAYDVWGDSVNTAARMESGGKVGEVNISHNTYEMVKDYFD 1223
Query: 449 LEEGEEV 455
+E +V
Sbjct: 1224 VEHRGKV 1230
>UniRef50_A0YS29 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC
8106|Rep: Adenylate cyclase - Lyngbya sp. PCC 8106
Length = 657
Score = 63.7 bits (148), Expect = 2e-08
Identities = 21/72 (29%), Positives = 46/72 (63%)
Query: 377 IQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHIS 436
+ +F+++ G +R+G+H G V+ G++G +F +D+W + V A++MES+G G++ ++
Sbjct: 562 LTQFNQQTGNNFLLRIGIHAGPVVAGVIGLSKFSYDLWGDTVNVASRMESNGVSGQIQVT 621
Query: 437 EETSQFLGGSYI 448
E + L ++
Sbjct: 622 SEVYERLKDQFV 633
>UniRef50_P33402 Cluster: Guanylate cyclase soluble subunit alpha-2;
n=39; Eumetazoa|Rep: Guanylate cyclase soluble subunit
alpha-2 - Homo sapiens (Human)
Length = 732
Score = 63.7 bits (148), Expect = 2e-08
Identities = 29/71 (40%), Positives = 45/71 (63%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+E +E G I MR+G+H+G+VL G+VG R ++ ++ N+VT A+K ES P R
Sbjct: 596 MMELSEEVLTPDGRPIQMRIGIHSGSVLAGVVGVRMPRYCLFGNNVTLASKFESGSHPRR 655
Query: 433 VHISEETSQFL 443
+++S T Q L
Sbjct: 656 INVSPTTYQLL 666
>UniRef50_A1ZQH6 Cluster: Heat-stable enterotoxin receptor; n=1;
Microscilla marina ATCC 23134|Rep: Heat-stable
enterotoxin receptor - Microscilla marina ATCC 23134
Length = 711
Score = 63.3 bits (147), Expect = 2e-08
Identities = 22/50 (44%), Positives = 39/50 (78%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
+R+G+HTG ++ G+VG ++F +D+W + V A++MES G+ G+V+IS +T
Sbjct: 629 LRLGIHTGEIIAGVVGKKKFAYDIWGDTVNLASRMESGGEAGKVNISGDT 678
>UniRef50_A0YQ82 Cluster: Adenylate cyclase; n=1; Lyngbya sp. PCC
8106|Rep: Adenylate cyclase - Lyngbya sp. PCC 8106
Length = 442
Score = 63.3 bits (147), Expect = 2e-08
Identities = 28/79 (35%), Positives = 45/79 (56%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M + I EF+ E MR+G+ G V+ G++G R+F +D+W + V A++MES G
Sbjct: 342 MQKTILEFNAETERKFQMRIGIAIGPVVAGVIGLRKFIYDLWGDTVNIASRMESHGIANE 401
Query: 433 VHISEETSQFLGGSYILEE 451
+ ++E T L Y LE+
Sbjct: 402 IQVTETTYHALKDDYSLEK 420
>UniRef50_Q4UFI5 Cluster: Cation-transporting ATPase; n=1; Theileria
annulata|Rep: Cation-transporting ATPase - Theileria
annulata
Length = 2559
Score = 63.3 bits (147), Expect = 2e-08
Identities = 32/87 (36%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
Query: 354 MDNVSILFADIVGFTRMS-SMIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKF 411
+DN + D+ M+ SMI I E + + MR+G+H G+ + G++G+ R ++
Sbjct: 2416 IDNQDMRIKDLENILLMAYSMIHIIDETSKIFNIPDLKMRIGLHYGSCIGGVIGSGRLRY 2475
Query: 412 DVWSNDVTFANKMESSGKPGRVHISEE 438
DVW DV AN +ES+G PG V +SE+
Sbjct: 2476 DVWGTDVYTANMIESNGVPGEVCVSEK 2502
Score = 57.2 bits (132), Expect = 1e-06
Identities = 29/112 (25%), Positives = 63/112 (56%), Gaps = 5/112 (4%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M++ E I +++G+++G V+ G+VG+++ ++ ++ + V A++M+ +G+ G
Sbjct: 1791 AMLQVATTIKLNNNESIGVKIGINSGYVISGLVGSKKPQYALFGDTVNTASRMKMTGEVG 1850
Query: 432 RVHISEETSQFLGGSYILEEGEEVFGHKTYFIEGRQVFCPYDREQCLTPSNP 483
++HISE T + + LE F ++ ++G+ V Y E+ L S P
Sbjct: 1851 KIHISESTYELVKNDKTLE-----FINREIEVKGKGVMNTYLLEKALGTSYP 1897
>UniRef50_Q4N3Z0 Cluster: Cation-transporting ATPase; n=1; Theileria
parva|Rep: Cation-transporting ATPase - Theileria parva
Length = 2664
Score = 63.3 bits (147), Expect = 2e-08
Identities = 32/87 (36%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
Query: 354 MDNVSILFADIVGFTRMS-SMIEAIQEFDRERG-EGINMRVGVHTGTVLCGIVGTRRFKF 411
+DN + D+ M+ SMI I E + + MR+G+H G+ + G++G+ R ++
Sbjct: 2521 IDNKDMRIQDLENILLMAYSMIHIIDETSKIFSIPDLKMRIGLHYGSCIGGVIGSGRLRY 2580
Query: 412 DVWSNDVTFANKMESSGKPGRVHISEE 438
DVW DV AN +ES+G PG V +SE+
Sbjct: 2581 DVWGTDVYTANMIESNGVPGEVCVSEK 2607
Score = 60.9 bits (141), Expect = 1e-07
Identities = 31/112 (27%), Positives = 64/112 (57%), Gaps = 5/112 (4%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M++ E I +++G+++G V+ G+VG+++ ++ ++ + V A++M+ +G+ G
Sbjct: 1824 AMLQVATTIKLNTNESIGVKIGINSGYVISGLVGSKKPQYALFGDTVNTASRMKMTGEVG 1883
Query: 432 RVHISEETSQFLGGSYILEEGEEVFGHKTYFIEGRQVFCPYDREQCLTPSNP 483
R+HISE T + + G LE F ++ ++G+ V Y E+ L S P
Sbjct: 1884 RIHISESTYELVKGDKTLE-----FINREIAVKGKGVMNTYLLEKALGTSYP 1930
>UniRef50_O01779 Cluster: Guanylate cyclase; n=1; Caenorhabditis
elegans|Rep: Guanylate cyclase - Caenorhabditis elegans
Length = 1146
Score = 63.3 bits (147), Expect = 2e-08
Identities = 34/94 (36%), Positives = 55/94 (58%), Gaps = 8/94 (8%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL-- 443
E IN+R+G++ G+V+ G+VG ++ ++ + V A++MES+GKPGR+H+S E + L
Sbjct: 1031 ERINLRIGINCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNGKPGRIHVSSEANHLLTH 1090
Query: 444 --GGSYILEEGEEVFGHK----TYFIEGRQVFCP 471
GG E GE + K TY++ G P
Sbjct: 1091 VVGGFRTEERGEVIIKGKGVMNTYWLLGENDSVP 1124
>UniRef50_A0EAN1 Cluster: Chromosome undetermined scaffold_86, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_86, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2476
Score = 63.3 bits (147), Expect = 2e-08
Identities = 28/72 (38%), Positives = 47/72 (65%), Gaps = 1/72 (1%)
Query: 373 MIEAIQEF-DRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
MI I++ D+ ++MR+G+HTG ++ G++GT ++D++ DV ANKMES + G
Sbjct: 2359 MINIIRKVRDKINNSDLHMRIGIHTGKIIGGVLGTDIVRYDIYGPDVLIANKMESKSERG 2418
Query: 432 RVHISEETSQFL 443
+V +SE T + L
Sbjct: 2419 QVQVSETTKKTL 2430
Score = 39.5 bits (88), Expect = 0.30
Identities = 22/89 (24%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Query: 350 NMSCMDNVSILFADIVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRF 409
N+ +N++ +F + M + Q F + E I +++GVH G V+ G++G +
Sbjct: 1757 NLISQNNINPVFRALQVAFEMQKFASS-QSFGQT--ENIVVKIGVHYGNVIAGVIGYHKP 1813
Query: 410 KFDVWSNDVTFANKMESSGKPGRVHISEE 438
+F + + V +++ S+ + ++ ISEE
Sbjct: 1814 QFSLIGDTVNTTSRVCSTAQDNQIKISEE 1842
>UniRef50_UPI0000586706 Cluster: PREDICTED: similar to guanylate
cyclase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to guanylate cyclase -
Strongylocentrotus purpuratus
Length = 650
Score = 62.5 bits (145), Expect = 4e-08
Identities = 32/89 (35%), Positives = 54/89 (60%), Gaps = 7/89 (7%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL- 443
G + +R+G+HTG V+ GIVG++ ++ ++ V A+KMES+G P R+ IS++ + L
Sbjct: 533 GTKMTLRIGIHTGPVVAGIVGSKMPRYCLFGETVNIASKMESNGLPNRIQISDDCHRILK 592
Query: 444 --GGSYILEEGEEVFGHK----TYFIEGR 466
GG ++ GE + K TY++ GR
Sbjct: 593 ITGGYTMVRRGEVLLTDKGTMTTYWLTGR 621
>UniRef50_A7RZH8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 622
Score = 62.5 bits (145), Expect = 4e-08
Identities = 33/102 (32%), Positives = 63/102 (61%), Gaps = 8/102 (7%)
Query: 372 SMIEAIQEFDRERG--EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
+M+ A+ E + G + + +R+G+HTGTV+ G+VG + ++ ++ + V A++MES+G
Sbjct: 521 NMLSAMPEIEDPAGLNDHLRIRIGIHTGTVVAGVVGLKMPRYCLFGDTVNTASRMESTGL 580
Query: 430 PGRVHISEETSQFLG-GSYILEEGEEV-----FGHKTYFIEG 465
+H+SE+T +FL +Y L++ + G KTY++ G
Sbjct: 581 AMAIHVSEDTQKFLAKANYALKQRGSMDIKGKGGMKTYWLLG 622
>UniRef50_UPI0000E49095 Cluster: PREDICTED: similar to guanylate
cyclase; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to guanylate cyclase -
Strongylocentrotus purpuratus
Length = 699
Score = 62.1 bits (144), Expect = 5e-08
Identities = 34/98 (34%), Positives = 59/98 (60%), Gaps = 7/98 (7%)
Query: 379 EFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEE 438
E +R E + +RVG+H+G V+ +VG + ++ ++ + V A++M+++G PGRV IS E
Sbjct: 550 EVPHKRNEKLTIRVGIHSGPVVAAVVGLKMPRYCLFGDTVNIASRMQTTGVPGRVQISYE 609
Query: 439 T---SQFLGGSYILEEGE-EVFGH---KTYFIEGRQVF 469
T LGG +++ GE E+ G TY++ G+ F
Sbjct: 610 TFAALNDLGGYKVVKRGEIEIKGKGLLTTYWLNGKDNF 647
>UniRef50_Q28S34 Cluster: Adenylate/guanylate cyclase; n=1;
Jannaschia sp. CCS1|Rep: Adenylate/guanylate cyclase -
Jannaschia sp. (strain CCS1)
Length = 417
Score = 62.1 bits (144), Expect = 5e-08
Identities = 27/83 (32%), Positives = 45/83 (54%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+E + EG +R+G+H G V+ G++G R+ +DVW V A++ME+ PGR
Sbjct: 318 MLEVARATSVALPEGFEIRIGLHVGPVVAGVIGNRKLFYDVWGETVNTASRMETYSAPGR 377
Query: 433 VHISEETSQFLGGSYILEEGEEV 455
+ I+ LG ++ E E+
Sbjct: 378 ILITPAARAQLGEDFMFEPRGEI 400
>UniRef50_A3WBP2 Cluster: Adenylate/guanylate cyclase; n=1;
Erythrobacter sp. NAP1|Rep: Adenylate/guanylate cyclase
- Erythrobacter sp. NAP1
Length = 420
Score = 62.1 bits (144), Expect = 5e-08
Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 1/78 (1%)
Query: 363 DIVGFTRMSS-MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFA 421
D V R + MI A+ ++ RE + +RVG+HTG V+ G++G +R +D W + + A
Sbjct: 302 DAVSAIRFAEQMIAAVTDYARETRIDVAIRVGIHTGPVVGGVIGQQRMAYDYWGDTMNTA 361
Query: 422 NKMESSGKPGRVHISEET 439
++E KPG + +SE T
Sbjct: 362 ARLEGVAKPGGIAVSEST 379
>UniRef50_Q5CUX5 Cluster: P-type ATpase fused to two adenyl cyclase
domains and 21 predicted transmembrane regions; n=2;
Cryptosporidium|Rep: P-type ATpase fused to two adenyl
cyclase domains and 21 predicted transmembrane regions -
Cryptosporidium parvum Iowa II
Length = 3848
Score = 62.1 bits (144), Expect = 5e-08
Identities = 38/127 (29%), Positives = 68/127 (53%), Gaps = 8/127 (6%)
Query: 329 NPLNSRISNPGSDIKSLFRPFNMSCMD-NVSIL--FADIVGFTRMSSMIEAIQE---FDR 382
NP++S+ S+ + + + N + N+S + + G R +M + E F R
Sbjct: 3661 NPISSKQSSSSNGSNNSYNTKNRQIYNLNISQMEGYTPAEGARRSIAMAHDMLEKIAFVR 3720
Query: 383 ERGE--GINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETS 440
E+ ++MR+G+H G + GIVG+ R +++VW +DV N+MES G PG + IS +
Sbjct: 3721 EKLSLPELSMRIGLHYGGCIGGIVGSSRLRYEVWGHDVIIGNRMESCGTPGNITISGQLH 3780
Query: 441 QFLGGSY 447
+ L ++
Sbjct: 3781 EVLSKNF 3787
Score = 47.2 bits (107), Expect = 0.002
Identities = 19/67 (28%), Positives = 43/67 (64%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSY 447
+ +++G+H+G V+ G+VGT + ++ ++ + V A++M+SS + G++ +S T +
Sbjct: 2865 LKLKIGIHSGRVISGVVGTNKPQYALFGDTVNTASRMKSSCETGKIQVSSMTHDLVKDIS 2924
Query: 448 ILEEGEE 454
IL+ E+
Sbjct: 2925 ILKWKEK 2931
>UniRef50_Q23310 Cluster: Guanylate cyclase; n=1; Caenorhabditis
elegans|Rep: Guanylate cyclase - Caenorhabditis elegans
Length = 1170
Score = 62.1 bits (144), Expect = 5e-08
Identities = 32/90 (35%), Positives = 55/90 (61%), Gaps = 8/90 (8%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL-- 443
E IN+R+G++ G+V+ G+VG ++ ++ + V A++MES+GKPG++H++ E +Q L
Sbjct: 1025 ERINLRIGINCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNGKPGKIHVTAEANQMLTQ 1084
Query: 444 --GGSYILEEGEEVFGHK----TYFIEGRQ 467
GG GE + K TY++ G Q
Sbjct: 1085 VVGGFRTESRGEVIIKGKGVMETYWLLGEQ 1114
>UniRef50_O96993 Cluster: Guanylate cyclase; n=1; Heterodera
glycines|Rep: Guanylate cyclase - Heterodera glycines
(Soybean cyst nematode worm)
Length = 1151
Score = 61.7 bits (143), Expect = 7e-08
Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Query: 381 DRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETS 440
D E +N+R+G H+G + G+VG ++ ++ + V A++MES+GK GRVHIS +
Sbjct: 1037 DHLPSERVNLRIGFHSGPAVAGVVGLTMPRYCLFGDSVNTASRMESNGKAGRVHISSSAN 1096
Query: 441 QFLG---GSYILEEGEEV 455
FL G Y+ E EV
Sbjct: 1097 HFLTSVIGGYVTEPRGEV 1114
>UniRef50_A7RN72 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 582
Score = 61.7 bits (143), Expect = 7e-08
Identities = 25/56 (44%), Positives = 41/56 (73%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQ 441
E + +R+G+HTG V+ G+VG + ++ ++ N VT ANKMES +PGR++IS +T +
Sbjct: 527 EPLKIRIGIHTGPVMAGVVGKKMPRYCLFGNTVTLANKMESGTQPGRINISIDTKR 582
>UniRef50_Q07093 Cluster: Head-specific guanylate cyclase; n=8;
Endopterygota|Rep: Head-specific guanylate cyclase -
Drosophila melanogaster (Fruit fly)
Length = 676
Score = 61.7 bits (143), Expect = 7e-08
Identities = 28/71 (39%), Positives = 45/71 (63%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
MI+A + GE I MR+G+HTGTVL G+VG + ++ ++ + VT ANK ES + +
Sbjct: 541 MIDACSKHITHDGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKFESGSEALK 600
Query: 433 VHISEETSQFL 443
+++S T +L
Sbjct: 601 INVSPTTKDWL 611
>UniRef50_A3I1K5 Cluster: Adenylate/guanylate cyclase; n=1;
Algoriphagus sp. PR1|Rep: Adenylate/guanylate cyclase -
Algoriphagus sp. PR1
Length = 420
Score = 61.3 bits (142), Expect = 9e-08
Identities = 25/63 (39%), Positives = 43/63 (68%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYI 448
+ R+G++TGTV+ G+VG +++ +D+W + V A ++E + PGRV+IS T Q + +
Sbjct: 336 DFRIGINTGTVVAGVVGDKKYVYDIWGDAVNTAARIEENSAPGRVNISAFTHQVVKEHFE 395
Query: 449 LEE 451
LEE
Sbjct: 396 LEE 398
>UniRef50_Q9GVB8 Cluster: Guanylyl cyclase enzyme; n=3;
Plasmodium|Rep: Guanylyl cyclase enzyme - Plasmodium
falciparum
Length = 3124
Score = 61.3 bits (142), Expect = 9e-08
Identities = 25/54 (46%), Positives = 38/54 (70%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQF 442
NMR+G+H G+ + GI+G+ R ++D+W DV ANK+ES+G PG + SE+ F
Sbjct: 3063 NMRIGLHYGSCVGGIIGSVRIRYDMWGLDVLIANKIESNGIPGEIICSEQFRHF 3116
Score = 53.6 bits (123), Expect = 2e-05
Identities = 21/87 (24%), Positives = 54/87 (62%), Gaps = 5/87 (5%)
Query: 380 FDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
+D+ + I++++G+HTG + G++G+ + ++ ++ + V A++M+S+ P +H+S +T
Sbjct: 1655 YDKYINKNISLKIGIHTGKAISGVIGSVKPQYALFGDTVNTASRMKSTSLPDHIHVSYDT 1714
Query: 440 SQFLGGSYILEEGEEVFGHKTYFIEGR 466
+ Y+ E+ ++ + FI+G+
Sbjct: 1715 YK-----YLKEDNTFIWKERKVFIKGK 1736
>UniRef50_UPI00015B6146 Cluster: PREDICTED: similar to
ENSANGP00000009149; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000009149 - Nasonia
vitripennis
Length = 1329
Score = 60.9 bits (141), Expect = 1e-07
Identities = 31/85 (36%), Positives = 54/85 (63%), Gaps = 5/85 (5%)
Query: 373 MIEAIQEFD-RERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
+++AI++F R R + + +R+G+H+G V G+VG + ++ ++ + V A++MES+G P
Sbjct: 976 LLDAIKQFSIRHRPLDKLQLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESTGSP 1035
Query: 431 GRVHISEETSQF---LGGSYILEEG 452
R+H S ET Q LGG + E G
Sbjct: 1036 LRIHCSTETKQLLDQLGGFSLAERG 1060
>UniRef50_A2DDF2 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1498
Score = 60.9 bits (141), Expect = 1e-07
Identities = 31/96 (32%), Positives = 63/96 (65%), Gaps = 7/96 (7%)
Query: 375 EAIQEFDRERGEGINMRVGVHTGTVLCG-IVGTRRFKFDVWSNDVTFANKMESSGKPGRV 433
+ +++ + + G+ +R+GV+TG L G ++GT + FD+ + + A++++S+ PG+V
Sbjct: 1379 KVMEQINVKLSAGLEVRIGVNTGGPLIGGVLGTDKPTFDIIGDPINVASRLQSTDIPGKV 1438
Query: 434 HISEETSQFLGGS-YILEEGEEVF----GHK-TYFI 463
IS+ET + + GS +++EE EV+ G++ TYF+
Sbjct: 1439 QISQETKEMIAGSNFVIEERGEVYLKGKGNRTTYFV 1474
>UniRef50_Q9ERL9 Cluster: Guanylate cyclase soluble subunit alpha-3;
n=16; Coelomata|Rep: Guanylate cyclase soluble subunit
alpha-3 - Mus musculus (Mouse)
Length = 691
Score = 60.9 bits (141), Expect = 1e-07
Identities = 27/71 (38%), Positives = 44/71 (61%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+E E GE I MR+G+H+G+V G+VG + ++ ++ N+VT ANK ES P +
Sbjct: 556 MMELSNEVMSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRK 615
Query: 433 VHISEETSQFL 443
+++S T + L
Sbjct: 616 INVSPTTYRLL 626
>UniRef50_Q02108 Cluster: Guanylate cyclase soluble subunit alpha-3;
n=12; Amniota|Rep: Guanylate cyclase soluble subunit
alpha-3 - Homo sapiens (Human)
Length = 690
Score = 60.9 bits (141), Expect = 1e-07
Identities = 27/71 (38%), Positives = 44/71 (61%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+E E GE I MR+G+H+G+V G+VG + ++ ++ N+VT ANK ES P +
Sbjct: 556 MMELSDEVMSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRK 615
Query: 433 VHISEETSQFL 443
+++S T + L
Sbjct: 616 INVSPTTYRLL 626
>UniRef50_A0LXB4 Cluster: Secreted protein containing
adenylate/guanylate cyclase catalytic domain; n=1;
Gramella forsetii KT0803|Rep: Secreted protein
containing adenylate/guanylate cyclase catalytic domain
- Gramella forsetii (strain KT0803)
Length = 610
Score = 60.5 bits (140), Expect = 2e-07
Identities = 27/86 (31%), Positives = 49/86 (56%)
Query: 370 MSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
M+ ++ +E ++RVG+++G V+ G+VGT++F +D+W + V A +MES
Sbjct: 500 MTQFVKETKENSLYDDANFDVRVGLNSGPVVAGVVGTKKFAYDIWGDTVNIAARMESHSD 559
Query: 430 PGRVHISEETSQFLGGSYILEEGEEV 455
G+++ISE T + + E EV
Sbjct: 560 IGKINISENTYDLIKDKFDCEYRGEV 585
>UniRef50_A2FPM7 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 713
Score = 60.5 bits (140), Expect = 2e-07
Identities = 27/84 (32%), Positives = 53/84 (63%), Gaps = 2/84 (2%)
Query: 374 IEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
++A++ D+E+ + + +RVGV+ G ++ G++GT + F+++ + A +ME +G P +
Sbjct: 616 LDAVERVDKEQNQKLRIRVGVNVGGPLVAGVLGTEKPTFEIFGPVIVMAQQMEHNGVPMK 675
Query: 433 VHISEETSQFL-GGSYILEEGEEV 455
VHIS + + GG Y +EE E+
Sbjct: 676 VHISRAVYELIYGGQYKIEERGEI 699
>UniRef50_Q7ZSZ5 Cluster: Soluble guanylyl cyclase alpha2 subunit;
n=5; Percomorpha|Rep: Soluble guanylyl cyclase alpha2
subunit - Oryzias latipes (Medaka fish) (Japanese
ricefish)
Length = 805
Score = 60.1 bits (139), Expect = 2e-07
Identities = 27/71 (38%), Positives = 45/71 (63%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+E +E G+ I +R+G+HTG+VL G+VG + ++ ++ N+VT A+K ES P
Sbjct: 665 MMELSEEVLTPDGKPIKLRIGIHTGSVLAGVVGVKMPRYCLFGNNVTLASKFESGSHPRC 724
Query: 433 VHISEETSQFL 443
+++S T Q L
Sbjct: 725 INVSPTTYQLL 735
>UniRef50_A1ZW48 Cluster: Adenylate cyclase; n=1; Microscilla marina
ATCC 23134|Rep: Adenylate cyclase - Microscilla marina
ATCC 23134
Length = 544
Score = 60.1 bits (139), Expect = 2e-07
Identities = 22/54 (40%), Positives = 42/54 (77%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+R+G++TG ++ G++G ++F +DVW + V A++MESSG+ G+V+IS +T + +
Sbjct: 432 LRLGINTGKLIAGVIGKKKFAYDVWGDTVNTASRMESSGEVGKVNISGKTYELV 485
>UniRef50_Q7JP51 Cluster: Guanylate cyclase; n=6; Caenorhabditis|Rep:
Guanylate cyclase - Caenorhabditis elegans
Length = 1111
Score = 60.1 bits (139), Expect = 2e-07
Identities = 29/77 (37%), Positives = 49/77 (63%), Gaps = 3/77 (3%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL-- 443
E IN+R+G++ G+V+ G+VG +F ++ + V A++MES+GKPG++H+S E ++ L
Sbjct: 987 ERINLRIGMNCGSVVAGVVGLTMPRFCLFGDAVNTASRMESNGKPGKIHVSAEANRMLHL 1046
Query: 444 -GGSYILEEGEEVFGHK 459
GG GE + K
Sbjct: 1047 VGGFDTESRGEVIIKGK 1063
>UniRef50_A2E4D6 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=6; cellular organisms|Rep:
Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1529
Score = 59.7 bits (138), Expect = 3e-07
Identities = 28/84 (33%), Positives = 51/84 (60%), Gaps = 2/84 (2%)
Query: 374 IEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
I AI + + G + +RVGVH G ++ G++GT + F+++ ++ A +ME +G P +
Sbjct: 1431 IAAIGRVNEKHGMSLRVRVGVHIGGPIVAGVIGTGKPTFEIFGPAISMAQQMEHNGVPMK 1490
Query: 433 VHISEETSQFL-GGSYILEEGEEV 455
VH+S + + GG+Y +EE E+
Sbjct: 1491 VHVSRSIYELIYGGTYKIEERGEI 1514
>UniRef50_Q03100 Cluster: Adenylate cyclase, aggregation specific;
n=1; Dictyostelium discoideum|Rep: Adenylate cyclase,
aggregation specific - Dictyostelium discoideum (Slime
mold)
Length = 1407
Score = 59.7 bits (138), Expect = 3e-07
Identities = 30/131 (22%), Positives = 67/131 (51%), Gaps = 7/131 (5%)
Query: 307 KLASNLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVG 366
K +N++N +++N +N N+ I+N G+D + D+ F ++
Sbjct: 550 KNKNNIINNN-NNSNSNNNNNNNSNNNNINNSGNDDD------DEEIEDSELEHFEKLID 602
Query: 367 FTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMES 426
++ ++E G + R G+ G+V G++G+++++FD+W + + ++ +E
Sbjct: 603 VAIEIMNLDVLKETGNTEGIQVQFRCGIAAGSVYGGVIGSQKYQFDIWGDTIARSHTLEQ 662
Query: 427 SGKPGRVHISE 437
G+PG+VH+ E
Sbjct: 663 LGQPGKVHVGE 673
Score = 44.8 bits (101), Expect = 0.008
Identities = 16/66 (24%), Positives = 37/66 (56%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYIL 449
+R+G+ G ++ G +G R KFDVW + A++M+S+ + + ++ + L +
Sbjct: 1276 VRIGISHGPLVAGCIGISRAKFDVWGDTANTASRMQSNAQDNEIMVTHSVYERLNKLFYF 1335
Query: 450 EEGEEV 455
++ +E+
Sbjct: 1336 DDEKEI 1341
>UniRef50_UPI00015B6145 Cluster: PREDICTED: similar to guanylate
cyclase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
to guanylate cyclase - Nasonia vitripennis
Length = 1542
Score = 59.3 bits (137), Expect = 3e-07
Identities = 26/68 (38%), Positives = 45/68 (66%), Gaps = 2/68 (2%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLG- 444
E + +R+G+HTG V+ G+VG ++ ++ + V A++MES+G+P R+HIS + L
Sbjct: 1062 ETLKLRIGIHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEPLRIHISAQCKDALDK 1121
Query: 445 -GSYILEE 451
G Y++EE
Sbjct: 1122 IGGYVIEE 1129
>UniRef50_A1ZJP1 Cluster: Adenylate cyclase; n=1; Microscilla marina
ATCC 23134|Rep: Adenylate cyclase - Microscilla marina
ATCC 23134
Length = 642
Score = 59.3 bits (137), Expect = 3e-07
Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
Query: 361 FADIV--GFTRMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDV 418
F DIV G SM + E + + R+G++TG ++ G++G +F +DVW + V
Sbjct: 494 FVDIVLAGLEIQRSMDQLKAEKEAKGEPFWETRLGINTGKLIAGVIGKNKFAYDVWGDTV 553
Query: 419 TFANKMESSGKPGRVHISEETSQFL 443
A++MESSG+ GRV+IS T + +
Sbjct: 554 NTASRMESSGEIGRVNISGVTYELV 578
>UniRef50_Q4Z354 Cluster: Guanylyl cyclase, putative; n=8; Plasmodium
(Vinckeia)|Rep: Guanylyl cyclase, putative - Plasmodium
berghei
Length = 1993
Score = 59.3 bits (137), Expect = 3e-07
Identities = 30/74 (40%), Positives = 48/74 (64%), Gaps = 4/74 (5%)
Query: 372 SMIEAIQEFDRERG--EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
SMI I+E RE+ +NMR+G+H G+ + G++G+ R ++D+W DV N M S+G
Sbjct: 1817 SMIRIIKEV-REKLCIPNLNMRIGLHYGSCVGGVIGSGRLRYDLWGIDVLTGNLM-SNGV 1874
Query: 430 PGRVHISEETSQFL 443
PG++++SE FL
Sbjct: 1875 PGKINVSETLKDFL 1888
Score = 50.4 bits (115), Expect = 2e-04
Identities = 17/52 (32%), Positives = 40/52 (76%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
I +++G+++G ++ G+VG+++ ++ ++ + V A++M+++GKP +HISE T
Sbjct: 1022 IRVKIGINSGRIIAGVVGSKKPQYALFGDTVNTASRMKTTGKPDYIHISEAT 1073
>UniRef50_A2FB45 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1552
Score = 59.3 bits (137), Expect = 3e-07
Identities = 35/98 (35%), Positives = 57/98 (58%), Gaps = 6/98 (6%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+I+ + E D + E + +RVGV+TG ++ G++GT + F++ + A++MES G P
Sbjct: 1454 VIKKLYEIDEKENEKLRIRVGVNTGGPIVAGVIGTEKPTFEILGPAINTAHEMESHGVPM 1513
Query: 432 RVHISEETSQFLGGSY--ILEEGE-EVFGHK--TYFIE 464
+VHIS + + G I+E GE EV K TY +E
Sbjct: 1514 KVHISRPVYELIYGQQFNIIERGEIEVKKGKMFTYIVE 1551
>UniRef50_A2DKP6 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=17; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1548
Score = 59.3 bits (137), Expect = 3e-07
Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 6/98 (6%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+I+ + E D E + +RVG++TG ++ G++GT + F++ + A++ME+ G P
Sbjct: 1450 VIKKLLEIDENENENLRIRVGINTGGPIVAGVIGTEKPTFEILGPAINIAHEMENKGVPM 1509
Query: 432 RVHISEETSQFLGGSY--ILEEGE-EVFGHK--TYFIE 464
+VHIS + + G I E GE +V G K TY +E
Sbjct: 1510 KVHISRPVYELIYGQQFDIKERGEIDVKGGKMFTYLVE 1547
>UniRef50_A0MJN0 Cluster: Guanylate cyclase beta; n=11; Plasmodium
(Vinckeia)|Rep: Guanylate cyclase beta - Plasmodium
berghei
Length = 2952
Score = 59.3 bits (137), Expect = 3e-07
Identities = 24/54 (44%), Positives = 37/54 (68%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQF 442
NMR+G+H G+ + GI+G+ R ++D+W DV AN +ES+G PG + SE+ F
Sbjct: 2891 NMRIGLHYGSCVGGIIGSVRIRYDMWGLDVLIANHIESNGIPGEIVCSEQFKNF 2944
Score = 50.0 bits (114), Expect = 2e-04
Identities = 33/175 (18%), Positives = 79/175 (45%), Gaps = 7/175 (4%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGG 445
+ I++R+G+HTG + G++G+ + ++ ++ + V A++M+S+ +H+S +T +
Sbjct: 1657 KNISLRIGIHTGKAISGVIGSVKPQYSLFGDTVNTASRMKSTSLKDHIHVSYDTYK---- 1712
Query: 446 SYILEEGEEVFGHKTYFIEGRQVFCPYDREQCLTPSNPVNLRXXXXXXXXXXXXXXXNYF 505
Y+ ++ V+ ++ FI+G+ Y L S + +
Sbjct: 1713 -YLKDDKTLVWKERSIFIKGKGEMKTYLLVDILDNSKKDHTKALEESTSSIFRSNDEIVN 1771
Query: 506 TAPLTPKTEDKLNLRKPNSNNFLSPTPFNFRAKASSLPSILDSDTELDDNRDKGL 560
+ L K ++ + P+ + + T F K S PS + ++ ++K +
Sbjct: 1772 KSELITKEKEFDKIEMPDKSEIIDETKKIF--KKSEKPSTKKKKIKKENAKEKNI 1824
>UniRef50_UPI0000DB755E Cluster: PREDICTED: similar to Adenylyl
cyclase 35C CG9210-PA, isoform A; n=1; Apis
mellifera|Rep: PREDICTED: similar to Adenylyl cyclase
35C CG9210-PA, isoform A - Apis mellifera
Length = 729
Score = 58.8 bits (136), Expect = 5e-07
Identities = 41/122 (33%), Positives = 65/122 (53%), Gaps = 9/122 (7%)
Query: 534 NFRAKASSLPSILDSDTELDDNRDKGLTERTDSSSKSPTSVGSYGKYTNKLKNWKVPRFL 593
N+R KA+SLPSILDS+ N D +T+ ++++KSP SV SYGK + K WK
Sbjct: 7 NYRMKANSLPSILDSE-----NGDTDITDEKENANKSPISVASYGKKKIRNKPWKY--LQ 59
Query: 594 RKHSDTPLHGIKKEDASDKTIHLLERGDVSVCVQSSNGYQQVPIVIESQDNKRPLQSSSK 653
R+ + + ++ E+A K I + S + NG++Q E + + P+ SS
Sbjct: 60 RQRTTEEMTPLEMEEA--KAIIAEQSKTESQSYEDRNGFRQNTSQSEIEMDPNPVPSSPL 117
Query: 654 LN 655
L+
Sbjct: 118 LS 119
Score = 54.4 bits (125), Expect = 1e-05
Identities = 23/83 (27%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 375 EAIQEFDRER-GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRV 433
+ I +F+R+ G + +R+G + G V G++G + +D+W + V A++M+S+G GR+
Sbjct: 622 KVINDFNRDLLGFKLILRIGFNYGDVTAGVIGATKLYYDIWGDAVNIASRMDSTGVAGRI 681
Query: 434 HISEETSQFLGGSYILEEGEEVF 456
+++ L Y E +V+
Sbjct: 682 QVAKNVLDVLSERYEFEPRGQVY 704
>UniRef50_UPI0000ECB130 Cluster: Guanylate cyclase soluble subunit
beta-2 (EC 4.6.1.2) (GCS-beta-2).; n=2; Gallus
gallus|Rep: Guanylate cyclase soluble subunit beta-2 (EC
4.6.1.2) (GCS-beta-2). - Gallus gallus
Length = 659
Score = 58.8 bits (136), Expect = 5e-07
Identities = 34/92 (36%), Positives = 51/92 (55%), Gaps = 6/92 (6%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL- 443
G I +RVG+HTG VL G+VG + ++ ++ + V A++MES G P ++H+S Q L
Sbjct: 560 GNPIQIRVGIHTGPVLAGVVGEKMPRYCLFGDTVNIASRMESHGVPSKIHLSSSAYQCLK 619
Query: 444 -GGSYILEEGE-EVFGH---KTYFIEGRQVFC 470
+ E GE EV G TYF+ + C
Sbjct: 620 YKNFEMTERGEIEVKGKGKMHTYFLVRNKTAC 651
>UniRef50_A7BYP5 Cluster: Adenylate/guanylate cyclase; n=1;
Beggiatoa sp. PS|Rep: Adenylate/guanylate cyclase -
Beggiatoa sp. PS
Length = 132
Score = 58.8 bits (136), Expect = 5e-07
Identities = 23/64 (35%), Positives = 46/64 (71%), Gaps = 1/64 (1%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSY-I 448
+R+G+HTG V+ G+VG +++ +DV+ + + A++MES+ +P +++ISE T Q + + +
Sbjct: 52 IRIGIHTGKVVGGVVGVKKYIYDVFGDSINTASRMESNSQPMKINISETTYQLVKDKFKV 111
Query: 449 LEEG 452
+E G
Sbjct: 112 IERG 115
>UniRef50_Q18331 Cluster: Guanylyl cyclase protein 11; n=2;
Caenorhabditis|Rep: Guanylyl cyclase protein 11 -
Caenorhabditis elegans
Length = 1032
Score = 58.8 bits (136), Expect = 5e-07
Identities = 27/72 (37%), Positives = 46/72 (63%), Gaps = 2/72 (2%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL-- 443
E + +R+G HTG V+ G+VG R ++ ++ + V AN MESSG+P R+ IS + + +
Sbjct: 914 EKLRLRIGNHTGPVVTGVVGIRMPRYCLFGDTVIIANMMESSGEPMRIQISSDAYELILK 973
Query: 444 GGSYILEEGEEV 455
G Y+ E+ E++
Sbjct: 974 CGGYVTEQREKI 985
>UniRef50_O75343 Cluster: Guanylate cyclase soluble subunit beta-2;
n=32; Euteleostomi|Rep: Guanylate cyclase soluble
subunit beta-2 - Homo sapiens (Human)
Length = 617
Score = 58.8 bits (136), Expect = 5e-07
Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 6/85 (7%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL- 443
GE I +RVG+HTG VL +VG + ++ ++ + V A++MES G P +VH+S + L
Sbjct: 479 GEPIQLRVGIHTGPVLADVVGDKMPRYCLFGDTVNTASRMESHGLPNKVHLSPTAYRALK 538
Query: 444 -GGSYILEEGE-EVFGH---KTYFI 463
G I+E GE EV G TYF+
Sbjct: 539 NQGFKIIERGEIEVKGKGRMTTYFL 563
>UniRef50_A5P476 Cluster: Putative adenylate/guanylate cyclase; n=1;
Methylobacterium sp. 4-46|Rep: Putative
adenylate/guanylate cyclase - Methylobacterium sp. 4-46
Length = 422
Score = 58.4 bits (135), Expect = 6e-07
Identities = 24/68 (35%), Positives = 39/68 (57%)
Query: 376 AIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHI 435
A+ E G I MR G+ TG V+ G++G R FDVW + V A+++E++ PG + +
Sbjct: 326 AVLETGERHGAAIQMRFGIATGQVISGVIGVTRPVFDVWGSTVNLASRLETASPPGAITL 385
Query: 436 SEETSQFL 443
T++ L
Sbjct: 386 DARTAELL 393
>UniRef50_A3HVA1 Cluster: Adenylate/guanylate cyclase; n=1;
Algoriphagus sp. PR1|Rep: Adenylate/guanylate cyclase -
Algoriphagus sp. PR1
Length = 464
Score = 58.4 bits (135), Expect = 6e-07
Identities = 25/71 (35%), Positives = 46/71 (64%), Gaps = 4/71 (5%)
Query: 373 MIEAIQEFDRERG----EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSG 428
M + +Q + +E+ E +RVG++TG V+ G+VG ++F FD+W + V A++++S
Sbjct: 359 MRDFVQSYAKEKPKHLQEYFQIRVGINTGPVVAGVVGLKKFSFDIWGDTVNTADRIQSGS 418
Query: 429 KPGRVHISEET 439
G+V++SE T
Sbjct: 419 VAGKVNVSEST 429
>UniRef50_A2G2M4 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=9; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1544
Score = 58.4 bits (135), Expect = 6e-07
Identities = 32/98 (32%), Positives = 57/98 (58%), Gaps = 6/98 (6%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+I+ + E D++ E + +RVG++TG ++ G++GT + F++ + A++ME G P
Sbjct: 1446 VIKKLLEIDQQENENLRIRVGINTGGPIIAGVIGTEKPTFEILGPAINTAHEMEHHGVPM 1505
Query: 432 RVHISEETSQFLGGSY--ILEEGE-EVFGHK--TYFIE 464
+VHIS + + G I E GE ++ G K TY +E
Sbjct: 1506 KVHISRPVYELIYGQQFDIKERGEIDIKGGKMFTYLVE 1543
>UniRef50_Q96KY6 Cluster: ADCY4 protein; n=20; Euteleostomi|Rep:
ADCY4 protein - Homo sapiens (Human)
Length = 130
Score = 58.4 bits (135), Expect = 6e-07
Identities = 28/94 (29%), Positives = 52/94 (55%), Gaps = 5/94 (5%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYIL 449
+RVG++ G V+ G++G ++ ++D+W N V A++MES+G G++ ++EET+ L
Sbjct: 36 LRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSL--- 92
Query: 450 EEGEEVFGHKTYFIEGRQVFCPYDREQCLTPSNP 483
G + ++G+ C Y LT + P
Sbjct: 93 --GYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGP 124
>UniRef50_A1ZXW2 Cluster: Adenylate cyclase; n=1; Microscilla marina
ATCC 23134|Rep: Adenylate cyclase - Microscilla marina
ATCC 23134
Length = 362
Score = 58.0 bits (134), Expect = 8e-07
Identities = 24/77 (31%), Positives = 48/77 (62%), Gaps = 1/77 (1%)
Query: 364 IVGFTRMSSMIEAIQEFDRERGEGI-NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFAN 422
++ M ++ +E +GE R+G+++G V+ G++G ++F +D+W + V A+
Sbjct: 231 VLAALEMQRFMKQKREEKASQGENYWQCRLGINSGEVIAGVIGRKKFAYDIWGDTVNSAS 290
Query: 423 KMESSGKPGRVHISEET 439
+MES+G+ G+V+IS T
Sbjct: 291 RMESNGEAGKVNISGST 307
>UniRef50_A1ZSW4 Cluster: Atrial natriuretic peptide receptor A;
n=1; Microscilla marina ATCC 23134|Rep: Atrial
natriuretic peptide receptor A - Microscilla marina ATCC
23134
Length = 562
Score = 58.0 bits (134), Expect = 8e-07
Identities = 22/61 (36%), Positives = 43/61 (70%), Gaps = 1/61 (1%)
Query: 384 RGEGI-NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQF 442
RGE + +R+G++TG ++ G++GT++F +DVW + V A++MES+G + +S+ T +
Sbjct: 445 RGEQVWELRLGINTGPLIAGVIGTKKFAYDVWGDTVNTASRMESNGVVNEISVSQVTYEL 504
Query: 443 L 443
+
Sbjct: 505 V 505
>UniRef50_Q47AI8 Cluster: Adenylyl cyclase class-3/4/guanylyl
cyclase; n=1; Dechloromonas aromatica RCB|Rep: Adenylyl
cyclase class-3/4/guanylyl cyclase - Dechloromonas
aromatica (strain RCB)
Length = 431
Score = 57.6 bits (133), Expect = 1e-06
Identities = 21/64 (32%), Positives = 40/64 (62%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSY 447
+++R+G+ TG V+ G+VG ++F +D+W + V A+++ S G PG + + T L G +
Sbjct: 336 LDVRIGIGTGPVVAGVVGKKKFIYDLWGDTVNLASRITSEGTPGMIQLDATTYHRLAGHF 395
Query: 448 ILEE 451
+E
Sbjct: 396 AFDE 399
>UniRef50_A4AWH6 Cluster: Adenylate/guanylate cyclase; n=1;
Flavobacteriales bacterium HTCC2170|Rep:
Adenylate/guanylate cyclase - Flavobacteriales bacterium
HTCC2170
Length = 394
Score = 57.6 bits (133), Expect = 1e-06
Identities = 22/67 (32%), Positives = 46/67 (68%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
M+ ++E ++ MRVG+H+GTV+ G+VG ++F +D++ + + A+++E +G+ G+
Sbjct: 298 MLSYLEERNKSHEIKWKMRVGIHSGTVVAGVVGKKKFAYDLFGDTINTASRIEFAGEVGK 357
Query: 433 VHISEET 439
++IS T
Sbjct: 358 INISSST 364
>UniRef50_Q8MLX0 Cluster: CG3216-PB, isoform B; n=7;
Endopterygota|Rep: CG3216-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 1141
Score = 57.6 bits (133), Expect = 1e-06
Identities = 28/87 (32%), Positives = 56/87 (64%), Gaps = 4/87 (4%)
Query: 373 MIEAIQEFD-RERGE-GINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
++ A+ F+ R + E I +R+G+H+G+V G+VG + + ++ + V A++MES+G+P
Sbjct: 1010 ILRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQP 1069
Query: 431 GRVHISEETSQFLG--GSYILEEGEEV 455
G++H+S T L G++ +E+ +V
Sbjct: 1070 GKIHVSSATKAILDKFGTFQMEQRGDV 1096
>UniRef50_Q7YXG2 Cluster: Soluble guanylyl cyclase 1 beta; n=1;
Limax marginatus|Rep: Soluble guanylyl cyclase 1 beta -
Limax marginatus
Length = 444
Score = 57.6 bits (133), Expect = 1e-06
Identities = 34/87 (39%), Positives = 54/87 (62%), Gaps = 6/87 (6%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLG 444
G + +RVGVHTG V+ G+VG + ++ ++ + V A++MES G PGR+H+S + L
Sbjct: 147 GLPLQIRVGVHTGPVVAGVVGVKMPRYCLFGDTVNTASRMESHGAPGRIHMSPTAYRALC 206
Query: 445 GS-YILEE-GE-EVFGH---KTYFIEG 465
S Y+ ++ G+ EV G TYF+ G
Sbjct: 207 SSGYVFKQRGQMEVKGKGVMSTYFLCG 233
>UniRef50_O97053 Cluster: Guanylate cyclase; n=1; Stichopus
japonicus|Rep: Guanylate cyclase - Stichopus japonicus
(Sea cucumber)
Length = 1075
Score = 57.6 bits (133), Expect = 1e-06
Identities = 35/107 (32%), Positives = 69/107 (64%), Gaps = 10/107 (9%)
Query: 369 RMS-SMIEAIQEFD-RERGEG-INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKME 425
RMS ++++ I+ F R R E + +R+G+H+G + G+VG + ++ ++ + V A++ME
Sbjct: 951 RMSLALLQRIKTFRIRHRSEERLKLRIGIHSGPAVAGVVGLKMPRYCLFGDTVNTASRME 1010
Query: 426 SSGKPGRVHISEETSQFLG--GSYILEE-GE-EVFG---HKTYFIEG 465
S+G+ ++H+S T + L G+++LE+ GE E+ G TY+++G
Sbjct: 1011 SNGEALKIHVSSSTKKILDLFGTFVLEKRGEIEMKGKGVQTTYWLQG 1057
>UniRef50_A2FZG6 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=4; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1552
Score = 57.6 bits (133), Expect = 1e-06
Identities = 32/98 (32%), Positives = 57/98 (58%), Gaps = 6/98 (6%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+I+ + + D + E + +RVG++TG ++ G++GT + F++ + A++ME+ G P
Sbjct: 1454 VIKKLLDIDEKENEKLRIRVGINTGGPIVAGVIGTEKPTFEILGPAINIAHEMENKGVPM 1513
Query: 432 RVHISEETSQFLGGSY--ILEEGE-EVFGHK--TYFIE 464
+VHIS + + G I E GE +V G K TY +E
Sbjct: 1514 KVHISRPVYELIYGQQFDIKERGEIDVKGGKMFTYLVE 1551
>UniRef50_UPI0000F2B0A8 Cluster: PREDICTED: similar to guanylyl
cyclase-G; n=6; Euteleostomi|Rep: PREDICTED: similar to
guanylyl cyclase-G - Monodelphis domestica
Length = 1111
Score = 57.2 bits (132), Expect = 1e-06
Identities = 25/68 (36%), Positives = 45/68 (66%), Gaps = 2/68 (2%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLG- 444
E + +R+G+HTG V+ G+VG ++ ++ + V A++MES+ P R+H+S+ T+ L
Sbjct: 967 EKLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESNSLPLRIHVSQTTASALRS 1026
Query: 445 -GSYILEE 451
G Y+L+E
Sbjct: 1027 VGGYVLQE 1034
>UniRef50_UPI0000E47CE0 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 364
Score = 57.2 bits (132), Expect = 1e-06
Identities = 46/157 (29%), Positives = 81/157 (51%), Gaps = 11/157 (7%)
Query: 218 VILGIIYSIVFEVLNIVLHLSEQEW-QASGMFVRILLQLCVHIIGV-HIYLMTFVRMRGT 275
V++G + + +L+ +L ++ + + I++ +CV+ IGV H +L+ V R T
Sbjct: 179 VVIGALTCLPHVILSAILGSHDEPIDKLLKILSNIVMFVCVNFIGVCHKHLLD-VAQRRT 237
Query: 276 FMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASNLMNEQVTEADTNVKTYHNPLNSRI 335
F+ + R +LE E+ +E+++ SV+P LA + E + +P S I
Sbjct: 238 FLDTRSCIESRIKLEHEQAQQERLLLSVLPAHLAYEMKTEMMARV-------RDPTMSPI 290
Query: 336 SNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMSS 372
S+ S + F + NVSIL+ADIVGFT ++S
Sbjct: 291 SHRPSS-STHFHSLYVKRHKNVSILYADIVGFTALAS 326
>UniRef50_UPI00005841ED Cluster: PREDICTED: similar to soluble
guanylyl cyclase beta 2 subunit; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to soluble guanylyl
cyclase beta 2 subunit - Strongylocentrotus purpuratus
Length = 645
Score = 57.2 bits (132), Expect = 1e-06
Identities = 25/55 (45%), Positives = 38/55 (69%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
GE I +RVG+HTG V+ G+VG + ++ ++ + V A++MES PG+VHIS T
Sbjct: 589 GEIIQIRVGIHTGPVVAGVVGVKMPRYCLFGDTVNTASRMESHSVPGKVHISPST 643
>UniRef50_A2DC46 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=2; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1572
Score = 56.8 bits (131), Expect = 2e-06
Identities = 31/97 (31%), Positives = 56/97 (57%), Gaps = 7/97 (7%)
Query: 374 IEAIQEFDRERGEGINMRVGVHTGTVLCG-IVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
I+++ E + I +R+GV++G L G ++G+ + FD+ + + A +++S+ PGR
Sbjct: 1453 IKSMDEINSNLESSIEVRIGVNSGGPLIGGVLGSDKPTFDIIGDTINVAARLQSTDIPGR 1512
Query: 433 VHISEETSQFLGG-SYILEEGEEVF-----GHKTYFI 463
+ ISE T + G YI+EE E+F KT+F+
Sbjct: 1513 IQISEGTKSLIDGLDYIIEERGEIFLKGKGNRKTFFV 1549
>UniRef50_A2DBX9 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=11; Eukaryota|Rep: Adenylate
and Guanylate cyclase catalytic domain containing protein
- Trichomonas vaginalis G3
Length = 1544
Score = 56.8 bits (131), Expect = 2e-06
Identities = 30/98 (30%), Positives = 57/98 (58%), Gaps = 6/98 (6%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+I+ + E D + E + +RVG++TG ++ G++GT + F++ + A++MES G P
Sbjct: 1446 VIKKLLEIDEQENEKLRIRVGINTGGPIVAGVIGTEKPTFEILGPAINIAHEMESHGIPM 1505
Query: 432 RVHISEETSQFL-GGSYILEEGEEVFGHK----TYFIE 464
+VHIS + + G ++ ++E E+ K TY +E
Sbjct: 1506 KVHISRSVYELIYGQNFDIKERGEIDVKKGKMFTYIVE 1543
>UniRef50_Q07553 Cluster: Guanylate cyclase 32E precursor; n=3;
Diptera|Rep: Guanylate cyclase 32E precursor - Drosophila
melanogaster (Fruit fly)
Length = 1163
Score = 56.8 bits (131), Expect = 2e-06
Identities = 33/89 (37%), Positives = 54/89 (60%), Gaps = 7/89 (7%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLG- 444
E + +R+GVH+G G+VG + ++ ++ + V A++MES+G R+HISE T Q L
Sbjct: 964 ETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQV 1023
Query: 445 -GSYI-LEEG-EEVFGH---KTYFIEGRQ 467
GSY+ +E G + G +TY++ RQ
Sbjct: 1024 IGSYVCIERGLTSIKGKGDMRTYWLTKRQ 1052
>UniRef50_UPI0000E4A009 Cluster: PREDICTED: similar to soluble
guanylyl cyclase beta-3; n=4; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to soluble guanylyl
cyclase beta-3 - Strongylocentrotus purpuratus
Length = 818
Score = 56.4 bits (130), Expect = 2e-06
Identities = 32/91 (35%), Positives = 56/91 (61%), Gaps = 8/91 (8%)
Query: 384 RGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+ E + +RVG+HTG V+ G+VG + ++ ++ + V A++MES+G+ ++H+SE T + L
Sbjct: 514 KDEIVKIRVGIHTGMVVAGVVGLKMPRYCLFGDTVNTASRMESTGEALKIHMSETTKKKL 573
Query: 444 G---GSYILEE--GEEVFGH---KTYFIEGR 466
G Y +EE V G KTY++ G+
Sbjct: 574 DQWEGYYDIEERGSTNVKGKGSMKTYWLHGK 604
>UniRef50_Q17BS6 Cluster: Guanylate cyclase; n=2; Culicidae|Rep:
Guanylate cyclase - Aedes aegypti (Yellowfever mosquito)
Length = 574
Score = 56.4 bits (130), Expect = 2e-06
Identities = 30/89 (33%), Positives = 55/89 (61%), Gaps = 7/89 (7%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQF---LG 444
+ +RVGV+TG + G+VGT ++ ++ + + A++MES+G+P ++H+SE T + LG
Sbjct: 459 LEIRVGVNTGPCVAGVVGTTMPRYCLFGDTINTASRMESTGEPMKIHLSENTKEILDKLG 518
Query: 445 GSYILEEGE-EVFGH---KTYFIEGRQVF 469
G I G EV G +T+++ G ++
Sbjct: 519 GFKIKRRGTIEVKGKGTMETFWLVGHTIY 547
Score = 35.1 bits (77), Expect = 6.5
Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Query: 233 IVLHLSEQEWQASGMFVRILLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEM- 291
+V +QE + + ++ I + L + II + L+ VR ++ LV R LE+
Sbjct: 270 VVFQTVDQEMRDARLYQTISIVLVLTIIVISPILVILVRNATDTIQDFSKELVTRTLELR 329
Query: 292 -EKQLKEKMIHSVMPPKLASNLMNEQVTEADT 322
EK +++++ ++PP + L ++ A+T
Sbjct: 330 CEKSKSDRLLYQMLPPAVVRQLKQQRQVPAET 361
>UniRef50_A2D8T2 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=6; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1540
Score = 56.4 bits (130), Expect = 2e-06
Identities = 35/108 (32%), Positives = 57/108 (52%), Gaps = 5/108 (4%)
Query: 358 SILFADIVGFTRMSSMIEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSN 416
S+ ++V F R + I+ I E D++ E + +RVGV+TG ++ GI+GT + F++
Sbjct: 1429 SVHAREVVEFGRQA--IKKILEIDQQHNEKLQIRVGVNTGGPIVAGILGTDKPTFEILGP 1486
Query: 417 DVTFANKMESSGKPGRVHISEETSQFLGGS--YILEEGEEVFGHKTYF 462
+ A +ME +G P VH+S + + G I E GE H F
Sbjct: 1487 AINMAQQMEHNGVPMNVHLSRAVYELIYGDKFEIKERGEIETNHGKVF 1534
>UniRef50_Q5YLC2 Cluster: Soluble guanylyl cyclase beta; n=1;
Chlamydomonas reinhardtii|Rep: Soluble guanylyl cyclase
beta - Chlamydomonas reinhardtii
Length = 991
Score = 56.0 bits (129), Expect = 3e-06
Identities = 23/53 (43%), Positives = 39/53 (73%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISE 437
GE + +RVG+H+G V+ G+VG + +F ++ + V A++MES G+ G++HISE
Sbjct: 565 GEPVRIRVGMHSGPVVAGVVGRKMPRFCLFGDTVNTASRMESHGEAGQIHISE 617
>UniRef50_Q03101 Cluster: Adenylate cyclase, germination specific;
n=3; Dictyostelium discoideum|Rep: Adenylate cyclase,
germination specific - Dictyostelium discoideum (Slime
mold)
Length = 858
Score = 56.0 bits (129), Expect = 3e-06
Identities = 23/56 (41%), Positives = 38/56 (67%), Gaps = 1/56 (1%)
Query: 387 GINMRVGVHTGTVLCGIV-GTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQ 441
G+ +RVG+H G V+ G++ G + FDVW + V A++MES+G G++H+S+ Q
Sbjct: 487 GLQVRVGIHCGPVISGVISGYAKPHFDVWGDTVNVASRMESTGIAGQIHVSDRVYQ 542
>UniRef50_A1ZSW5 Cluster: Adenylate cyclase; n=1; Microscilla marina
ATCC 23134|Rep: Adenylate cyclase - Microscilla marina
ATCC 23134
Length = 408
Score = 55.6 bits (128), Expect = 4e-06
Identities = 21/54 (38%), Positives = 39/54 (72%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+R+G++TG ++ G++G +F +DVW + V A++MES+G+ +V+IS T Q +
Sbjct: 297 LRLGINTGPLVAGVIGKNKFAYDVWGDTVNTASRMESNGEVNKVNISGVTHQLV 350
>UniRef50_Q9GT36 Cluster: Guanylate cyclase; n=1; Heterodera
glycines|Rep: Guanylate cyclase - Heterodera glycines
(Soybean cyst nematode worm)
Length = 1112
Score = 55.6 bits (128), Expect = 4e-06
Identities = 22/58 (37%), Positives = 39/58 (67%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
E + +R+G+HTG+ + G+VG ++ ++ + + A ++ESS KP R+HIS T+ FL
Sbjct: 1003 ERLRLRIGIHTGSTVAGVVGLSMPRYCLFGDTINTAARLESSSKPMRIHISTTTNHFL 1060
>UniRef50_Q8TA72 Cluster: Guanylate cyclase; n=2; Eumetazoa|Rep:
Guanylate cyclase - Asterias amurensis (Starfish)
Length = 1067
Score = 55.6 bits (128), Expect = 4e-06
Identities = 31/103 (30%), Positives = 59/103 (57%), Gaps = 9/103 (8%)
Query: 373 MIEAIQEF--DRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
++E + F +R E + +R+G+H+G+ + G+VG ++ ++ + V A++MES+G
Sbjct: 949 LLEEVTTFVVPHKRDEKLKLRIGIHSGSCVAGVVGLTMPRYCLFGDTVNTASRMESNGLA 1008
Query: 431 GRVHISEETSQF---LGGSYILEEGEEVFGHK----TYFIEGR 466
++H+S E Q LGG ++E G K TY++EG+
Sbjct: 1009 LKIHVSPECRQVLQELGGYNLVERGLVAMKGKGEILTYWLEGQ 1051
>UniRef50_A2FSM3 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1416
Score = 55.6 bits (128), Expect = 4e-06
Identities = 32/97 (32%), Positives = 56/97 (57%), Gaps = 7/97 (7%)
Query: 374 IEAIQEFDRERGEGINMRVGVHTGTVLCG-IVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
I+++ + + + +RVGV++G L G ++GT + FD+ + + A +++S+ PG
Sbjct: 1299 IKSMTDINTNLESSLEVRVGVNSGGPLIGGVLGTDKPTFDIIGDPINVAARLQSTDIPGN 1358
Query: 433 VHISEETSQFLGGS-YILEEGEEVF-----GHKTYFI 463
V ISEET + S +I+EE EV+ KTYF+
Sbjct: 1359 VQISEETKNLIESSDFIIEERGEVYLKGKGNRKTYFV 1395
>UniRef50_Q6TL19 Cluster: Guanylate cyclase 2G precursor; n=6;
Murinae|Rep: Guanylate cyclase 2G precursor - Mus
musculus (Mouse)
Length = 1100
Score = 55.6 bits (128), Expect = 4e-06
Identities = 30/91 (32%), Positives = 55/91 (60%), Gaps = 7/91 (7%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL-- 443
E + +R+G+HTG V+ G+VG ++ ++ + V A++MESS P R+H+S+ T+ L
Sbjct: 992 ERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESSSLPLRIHVSQSTAGALLA 1051
Query: 444 -GGSYILEEGE-EVFG---HKTYFIEGRQVF 469
GG ++ + G V G T++++G+ F
Sbjct: 1052 AGGYHLQKRGTISVKGKGEQTTFWLKGKDGF 1082
>UniRef50_A3HV63 Cluster: Adenylate or guanylate cyclase; n=1;
Algoriphagus sp. PR1|Rep: Adenylate or guanylate cyclase
- Algoriphagus sp. PR1
Length = 638
Score = 55.2 bits (127), Expect = 6e-06
Identities = 22/55 (40%), Positives = 39/55 (70%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+MR G+++G V+ GIVG ++F++D+W + V A +ME+S + +++ISE T L
Sbjct: 549 DMRCGINSGPVVAGIVGIKKFQYDIWGDTVNTAQRMEASCEINQINISENTYSLL 603
>UniRef50_Q6UCJ4 Cluster: Guanylate cyclase PcGC-M2 precursor; n=5;
Pleocyemata|Rep: Guanylate cyclase PcGC-M2 precursor -
Procambarus clarkii (Red swamp crayfish)
Length = 1423
Score = 55.2 bits (127), Expect = 6e-06
Identities = 25/63 (39%), Positives = 43/63 (68%), Gaps = 2/63 (3%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLG--GSY 447
+R+G+HTG V+ G+VG ++ ++ + V A++MES+G+P R+HISE+ L G Y
Sbjct: 1093 LRIGLHTGPVIAGVVGLTMPRYCLFGDTVNTASRMESNGEPLRIHISEQCHIALKNLGGY 1152
Query: 448 ILE 450
++E
Sbjct: 1153 VME 1155
>UniRef50_UPI00015B48AF Cluster: PREDICTED: similar to
ENSANGP00000014144; n=2; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000014144 - Nasonia
vitripennis
Length = 1648
Score = 54.8 bits (126), Expect = 8e-06
Identities = 27/83 (32%), Positives = 52/83 (62%), Gaps = 4/83 (4%)
Query: 372 SMIEAIQEFD--RERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
++++A++ F ++ +++R+GVH+G V G+VG + + ++ + V A++MESSG
Sbjct: 1494 AILDAVKSFTIIHKQDAQLSVRIGVHSGPVCAGVVGQKMPHYCLFGDTVNTASRMESSGL 1553
Query: 430 PGRVHISEETSQFLG--GSYILE 450
P R+H+S T L G++ LE
Sbjct: 1554 PLRIHVSRATKDILDKYGTFDLE 1576
>UniRef50_Q73RD3 Cluster: Adenylate/guanylate cyclase catalytic
domain protein; n=1; Treponema denticola|Rep:
Adenylate/guanylate cyclase catalytic domain protein -
Treponema denticola
Length = 1075
Score = 54.8 bits (126), Expect = 8e-06
Identities = 23/80 (28%), Positives = 47/80 (58%)
Query: 372 SMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+M+ +++ F++E ++++G+ +G + GIVG ++ FDV+ + V A ++ES P
Sbjct: 917 AMLRSLETFNKENDSCFSIKIGISSGAITGGIVGVHKYIFDVFGDTVNTAFRLESVTSPT 976
Query: 432 RVHISEETSQFLGGSYILEE 451
+SE T+ + G Y L +
Sbjct: 977 ACTVSESTAALIRGKYGLHK 996
>UniRef50_Q15T90 Cluster: Adenylate/guanylate cyclase; n=1;
Pseudoalteromonas atlantica T6c|Rep: Adenylate/guanylate
cyclase - Pseudoalteromonas atlantica (strain T6c /
BAA-1087)
Length = 407
Score = 54.8 bits (126), Expect = 8e-06
Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 5/81 (6%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYIL 449
+R+G+ +G V+ G++G +F +D+W VT A +MES G+ ++ +++ T + Y
Sbjct: 324 LRIGIGSGEVVAGVIGRSKFCYDLWGEAVTLAARMESHGRTDQIQVTQSTYEMAKHKYCF 383
Query: 450 EEGEEV----FGH-KTYFIEG 465
E EV G KTY++ G
Sbjct: 384 EPRGEVKIKGLGQIKTYWLLG 404
>UniRef50_Q1EC29 Cluster: IP04501p; n=7; Endopterygota|Rep: IP04501p
- Drosophila melanogaster (Fruit fly)
Length = 710
Score = 54.8 bits (126), Expect = 8e-06
Identities = 24/57 (42%), Positives = 40/57 (70%)
Query: 382 RERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEE 438
R E + +R GVHTG V+ GIVGT+ ++ ++ + V A++MES+G+ ++HI+EE
Sbjct: 581 RAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEE 637
>UniRef50_A2DTD4 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 475
Score = 54.8 bits (126), Expect = 8e-06
Identities = 33/97 (34%), Positives = 54/97 (55%), Gaps = 6/97 (6%)
Query: 374 IEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
I ++++ D E G+ + +RVGV+TG ++ G++G R F++ + A +ME G P +
Sbjct: 373 IRSVRQLDEELGQQLQIRVGVNTGGPIVAGVLGVGRPTFEILGPAINMAQQMEHHGVPMK 432
Query: 433 VHISEETSQ--FLGGSYILEEGE-EVFGHK--TYFIE 464
VHIS + + G I E GE EV K TY ++
Sbjct: 433 VHISRSVYENIYESGFVIHERGEVEVKNGKVTTYLVD 469
>UniRef50_Q5SR07 Cluster: Natriuretic peptide receptor A/guanylate
cyclase A; n=14; cellular organisms|Rep: Natriuretic
peptide receptor A/guanylate cyclase A - Homo sapiens
(Human)
Length = 255
Score = 54.8 bits (126), Expect = 8e-06
Identities = 25/74 (33%), Positives = 49/74 (66%), Gaps = 2/74 (2%)
Query: 372 SMIEAIQEFD-RERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
++++A++ F R R E + +R+G+HTG V G+VG + ++ ++ + V A++MES+G+
Sbjct: 132 ALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGE 191
Query: 430 PGRVHISEETSQFL 443
++H+S ET L
Sbjct: 192 ALKIHLSSETKAVL 205
>UniRef50_P16066 Cluster: Atrial natriuretic peptide receptor A
precursor; n=57; Chordata|Rep: Atrial natriuretic peptide
receptor A precursor - Homo sapiens (Human)
Length = 1061
Score = 54.8 bits (126), Expect = 8e-06
Identities = 25/74 (33%), Positives = 49/74 (66%), Gaps = 2/74 (2%)
Query: 372 SMIEAIQEFD-RERG-EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
++++A++ F R R E + +R+G+HTG V G+VG + ++ ++ + V A++MES+G+
Sbjct: 951 ALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGE 1010
Query: 430 PGRVHISEETSQFL 443
++H+S ET L
Sbjct: 1011 ALKIHLSSETKAVL 1024
>UniRef50_Q02153 Cluster: Guanylate cyclase soluble subunit beta-1;
n=40; Coelomata|Rep: Guanylate cyclase soluble subunit
beta-1 - Homo sapiens (Human)
Length = 619
Score = 54.4 bits (125), Expect = 1e-05
Identities = 34/133 (25%), Positives = 66/133 (49%), Gaps = 8/133 (6%)
Query: 311 NLMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRM 370
NL+N+ T DT + NP ++ G + +S + I A + +
Sbjct: 448 NLLNDLYTRFDTLTDSRKNPFVYKVETVGD------KYMTVSGLPEPCIHHARSICHLAL 501
Query: 371 SSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
M A Q + GE + + +G+HTG V+ G++G R ++ ++ N V ++ E++G+
Sbjct: 502 DMMEIAGQV--QVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEK 559
Query: 431 GRVHISEETSQFL 443
G++++SE T + L
Sbjct: 560 GKINVSEYTYRCL 572
>UniRef50_UPI0000E4745B Cluster: PREDICTED: similar to
ENSANGP00000009149; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to ENSANGP00000009149
- Strongylocentrotus purpuratus
Length = 1319
Score = 53.6 bits (123), Expect = 2e-05
Identities = 26/83 (31%), Positives = 52/83 (62%), Gaps = 4/83 (4%)
Query: 373 MIEAIQEFD-RERGE-GINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
++E ++ F R R E + +R+G+H+G+ + G+VG ++ ++ + V A++MES+G+
Sbjct: 1038 LLEDVKAFKVRHRPEVNLKLRIGIHSGSTVSGVVGLTMPRYCLFGDTVNTASRMESNGEA 1097
Query: 431 GRVHISEETSQFLG--GSYILEE 451
++H S ET L G +++EE
Sbjct: 1098 LKIHTSSETKNLLEQMGGFVVEE 1120
>UniRef50_Q7UN49 Cluster: Adenylate cyclase 1; n=1; Pirellula
sp.|Rep: Adenylate cyclase 1 - Rhodopirellula baltica
Length = 719
Score = 53.6 bits (123), Expect = 2e-05
Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 369 RMSSMIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGT-RRFKFDVWSNDVTFANKMESS 427
R S + IQE R G+++ +G+HTG + G VGT +R ++ N V A+++
Sbjct: 609 RASRVAWRIQEALRSHKSGLSIGIGIHTGQAVVGNVGTPQRMEYTAIGNTVNVASRLCDR 668
Query: 428 GKPGRVHISEETSQFLGGSYILEEGE 453
G + +S E SQ L S++LE E
Sbjct: 669 ALAGEIVVSGEVSQQLSNSFVLEANE 694
>UniRef50_Q9VF17 Cluster: Guanylate cyclase; n=7; Endopterygota|Rep:
Guanylate cyclase - Drosophila melanogaster (Fruit fly)
Length = 1417
Score = 53.6 bits (123), Expect = 2e-05
Identities = 25/74 (33%), Positives = 48/74 (64%), Gaps = 2/74 (2%)
Query: 372 SMIEAIQEFD-RERGEG-INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
+++EA+ F R E + +R+G+HTG + G+VG + ++ ++ + V A++MES+G+
Sbjct: 1028 ALLEAVHNFRIHHRPEDRLKLRIGLHTGACVAGVVGLKMPRYCLFGDTVNTASRMESNGE 1087
Query: 430 PGRVHISEETSQFL 443
++HISE T + L
Sbjct: 1088 ALKIHISETTKEAL 1101
>UniRef50_Q8T8L6 Cluster: Guanylate cyclase; n=5; Caenorhabditis|Rep:
Guanylate cyclase - Caenorhabditis elegans
Length = 1276
Score = 53.6 bits (123), Expect = 2e-05
Identities = 19/58 (32%), Positives = 43/58 (74%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
E + +R+G+H+G+V+ G+VG++ ++ ++ + V +++MES+G P ++H+S++T L
Sbjct: 1176 EQLKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGLPLKIHVSQQTYDIL 1233
>UniRef50_Q8IQK2 Cluster: Guanylate cyclase; n=6; Diptera|Rep:
Guanylate cyclase - Drosophila melanogaster (Fruit fly)
Length = 1272
Score = 53.6 bits (123), Expect = 2e-05
Identities = 29/85 (34%), Positives = 50/85 (58%), Gaps = 5/85 (5%)
Query: 373 MIEAIQEFD-RERGEG-INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
++ A+ EF R R + +R+G+H+G V G+VG + ++ ++ + V A++MESSG P
Sbjct: 1020 LLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESSGVP 1079
Query: 431 GRVHISEETSQF---LGGSYILEEG 452
++H S + Q LGG + E G
Sbjct: 1080 LKIHCSWQCRQLLDRLGGYHFAERG 1104
>UniRef50_A7SPS9 Cluster: Predicted protein; n=11; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 518
Score = 53.6 bits (123), Expect = 2e-05
Identities = 27/88 (30%), Positives = 54/88 (61%), Gaps = 4/88 (4%)
Query: 373 MIEAIQEFD-RER-GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
M+ I F R R + + +R+G+H+G+ + G+VG + ++ ++ + V A++MES+G+
Sbjct: 415 MLREIDSFKIRHRPNDKLKLRIGIHSGSCVAGVVGKKMPRYCLFGDTVNTASRMESNGEA 474
Query: 431 GRVHISEETSQFLG--GSYILEEGEEVF 456
++HIS T + L G Y +++ +VF
Sbjct: 475 LKIHISPSTKRILDELGGYHIQKRGKVF 502
Score = 36.3 bits (80), Expect = 2.8
Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 13/103 (12%)
Query: 287 RQLEMEKQ--LKEKMIHSVMPPKLASNL---MNEQVTE-ADTNVKTYHNPLNSRISNPGS 340
R+L M KQ + + M++ + K A+NL + E+ ++ AD KT N LN + P S
Sbjct: 265 RKLPMGKQSNIMDNMVNLL--EKYANNLESLVEERTSQLADEKRKT-ENLLNRML--PPS 319
Query: 341 DIKSLFRPFNMSC--MDNVSILFADIVGFTRMSSMIEAIQEFD 381
K L ++ D VSI F+DIVGFT +SS +Q D
Sbjct: 320 VAKDLVHGKQVTAENFDEVSIFFSDIVGFTSLSSESTPLQVVD 362
>UniRef50_Q9VA09 Cluster: CG1470-PA; n=6; Diptera|Rep: CG1470-PA -
Drosophila melanogaster (Fruit fly)
Length = 787
Score = 53.2 bits (122), Expect = 2e-05
Identities = 19/56 (33%), Positives = 39/56 (69%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+ + +G+H+G V+ G++G R ++ ++ N V ++ E++G PGR+++SEET + L
Sbjct: 627 VQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLL 682
>UniRef50_Q9GT37 Cluster: Guanylate cyclase; n=2; Heterodera
glycines|Rep: Guanylate cyclase - Heterodera glycines
(Soybean cyst nematode worm)
Length = 1174
Score = 53.2 bits (122), Expect = 2e-05
Identities = 28/89 (31%), Positives = 50/89 (56%), Gaps = 7/89 (7%)
Query: 374 IEAIQEF--DRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+ ++Q F + I +R+G+H+G + G+VG ++ ++ + V A++MESS
Sbjct: 1029 LNSLQSFRISEHSDQRIRLRIGLHSGPCVAGVVGLAMPRYCLFGDTVNTASRMESSSSAN 1088
Query: 432 RVHISEETSQFL-----GGSYILEEGEEV 455
++HIS+ET L GG+Y+ E EV
Sbjct: 1089 KIHISKETCILLHENSEGGAYLTESRGEV 1117
>UniRef50_Q19768 Cluster: Guanylate cyclase; n=2;
Caenorhabditis|Rep: Guanylate cyclase - Caenorhabditis
elegans
Length = 1025
Score = 53.2 bits (122), Expect = 2e-05
Identities = 21/62 (33%), Positives = 40/62 (64%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGG 445
E + +R+G+H+G+ + G+VG ++ ++ + V A++MES+GKPG +H+S + L
Sbjct: 932 EKVQIRIGMHSGSCVAGVVGLTMPRYCLFGDTVNTASRMESNGKPGFIHLSSDCYDLLTS 991
Query: 446 SY 447
Y
Sbjct: 992 LY 993
>UniRef50_Q174S2 Cluster: Guanylate cyclase; n=7; Coelomata|Rep:
Guanylate cyclase - Aedes aegypti (Yellowfever mosquito)
Length = 1292
Score = 53.2 bits (122), Expect = 2e-05
Identities = 24/74 (32%), Positives = 48/74 (64%), Gaps = 2/74 (2%)
Query: 372 SMIEAIQEFD-RER-GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
+++ A+ +F R R E + +R+G+H+G + G+VG + ++ ++ + V A++MES+G+
Sbjct: 1087 ALLAAVHKFTIRHRPNEQLKLRIGLHSGPCVAGVVGLKMPRYCLFGDTVNTASRMESNGE 1146
Query: 430 PGRVHISEETSQFL 443
P ++HIS T L
Sbjct: 1147 PLKIHISHTTKTLL 1160
>UniRef50_A2EEV5 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=3; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1564
Score = 53.2 bits (122), Expect = 2e-05
Identities = 27/104 (25%), Positives = 60/104 (57%), Gaps = 6/104 (5%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHT-GTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+++ I +R +++R+GV++ G V+ G++G+ + FD+ + + A +++S+G P
Sbjct: 1453 VVDEIDNINRCLESHLSIRIGVNSSGPVIAGVLGSDKPLFDIIGDPINVAARLQSTGSPN 1512
Query: 432 RVHISEETSQFLGGS--YILEEGEEVF---GHKTYFIEGRQVFC 470
+VH+S+ T + L + YI + G+ G +T ++ +FC
Sbjct: 1513 QVHVSQATYELLKDTDFYISKVGDTFLKGKGVQTTYVVSNPIFC 1556
>UniRef50_Q4T0M0 Cluster: Guanylate cyclase; n=1; Tetraodon
nigroviridis|Rep: Guanylate cyclase - Tetraodon
nigroviridis (Green puffer)
Length = 1001
Score = 52.8 bits (121), Expect = 3e-05
Identities = 23/74 (31%), Positives = 48/74 (64%), Gaps = 2/74 (2%)
Query: 372 SMIEAIQEFD-RER-GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
+++E ++ F R R + + +R+G+HTG V G+VG + ++ ++ + V A++MES+G+
Sbjct: 909 ALLEQVKTFKIRHRPNDQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGE 968
Query: 430 PGRVHISEETSQFL 443
++H+S T + L
Sbjct: 969 ALKIHVSSATKEVL 982
>UniRef50_A2ES71 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=3; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1523
Score = 52.8 bits (121), Expect = 3e-05
Identities = 26/84 (30%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
Query: 374 IEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
IE ++ + E + + +RVGV+TG ++ G++GT + F++ + A +ME G P +
Sbjct: 1423 IEGLERVNEEINQKLQIRVGVNTGGPIVAGVLGTDKPTFEILGPAINMAQQMEHHGVPMK 1482
Query: 433 VHISEETSQFL-GGSYILEEGEEV 455
VH+S + + GG + ++E EV
Sbjct: 1483 VHVSRAVYELIYGGPFDIKERGEV 1506
>UniRef50_UPI0000D5787E Cluster: PREDICTED: similar to CG9783-PA; n=2;
Endopterygota|Rep: PREDICTED: similar to CG9783-PA -
Tribolium castaneum
Length = 1044
Score = 52.4 bits (120), Expect = 4e-05
Identities = 25/68 (36%), Positives = 41/68 (60%), Gaps = 2/68 (2%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL- 443
G + +R+G+HTG G+VG ++ ++ + V A++MES+G R+H+SE T + L
Sbjct: 942 GTPLRLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIHLSEATKERLE 1001
Query: 444 -GGSYILE 450
G Y LE
Sbjct: 1002 KAGGYQLE 1009
>UniRef50_UPI000069F10A Cluster: Adenylate cyclase type 6 (EC
4.6.1.1) (Adenylate cyclase type VI) (ATP
pyrophosphate-lyase 6) (Adenylyl cyclase 6)
(Ca(2+)-inhibitable adenylyl cyclase).; n=2;
Coelomata|Rep: Adenylate cyclase type 6 (EC 4.6.1.1)
(Adenylate cyclase type VI) (ATP pyrophosphate-lyase 6)
(Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl
cyclase). - Xenopus tropicalis
Length = 355
Score = 52.4 bits (120), Expect = 4e-05
Identities = 19/69 (27%), Positives = 41/69 (59%)
Query: 375 EAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVH 434
E ++ + M++G++ G V+ G++G R+ ++D+W N V A++M+S+G P +
Sbjct: 255 EQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGLPDCIQ 314
Query: 435 ISEETSQFL 443
++ + Q L
Sbjct: 315 VTTDLYQVL 323
>UniRef50_Q17AF9 Cluster: Guanylate cyclase; n=1; Aedes aegypti|Rep:
Guanylate cyclase - Aedes aegypti (Yellowfever mosquito)
Length = 987
Score = 52.4 bits (120), Expect = 4e-05
Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 2/75 (2%)
Query: 379 EFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEE 438
E GE I +R+G+H+G + G+VG + ++ ++ + V A++MES+G ++HIS
Sbjct: 896 EIRHRPGEFIQIRIGIHSGQCVAGVVGLKMPRYCLFGDTVNTASRMESTGDAMKIHISSV 955
Query: 439 TSQFLG--GSYILEE 451
T L G Y EE
Sbjct: 956 TYNLLKKIGGYRFEE 970
>UniRef50_A2DFE4 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=5; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1681
Score = 52.4 bits (120), Expect = 4e-05
Identities = 24/87 (27%), Positives = 54/87 (62%), Gaps = 3/87 (3%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTG-TVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
+++AI+E + + + +R+GV++G ++ G++GT + FD+ + + A +++S+ PG
Sbjct: 1573 VLDAIEELNEQLNASLMVRIGVNSGGPIIAGVLGTDKPLFDIIGDTINVAARLQSTDIPG 1632
Query: 432 RVHISEETSQFLG--GSYILEEGEEVF 456
V IS+ T + + G + +EE E++
Sbjct: 1633 NVQISKGTYEIVAGEGKFHIEERGEIY 1659
>UniRef50_Q4TAT8 Cluster: Guanylate cyclase; n=2; Tetraodontidae|Rep:
Guanylate cyclase - Tetraodon nigroviridis (Green puffer)
Length = 1154
Score = 52.0 bits (119), Expect = 5e-05
Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 5/87 (5%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLG--- 444
+ +R+G+H+G V+ G+VG ++ ++ + VT A+ ME+SG P R+HIS T + L
Sbjct: 1037 VKIRIGLHSGPVVAGVVGLTMPRYCLFGDTVTTASHMEASGLPYRIHISLSTVKVLTSLK 1096
Query: 445 -GSYILEEGEEVFGH-KTYFIEGRQVF 469
G ++ +V G TY++ GR F
Sbjct: 1097 LGYHMETRKAQVKGAVDTYWLVGRDGF 1123
>UniRef50_Q4SW10 Cluster: Guanylate cyclase; n=4; Tetraodontidae|Rep:
Guanylate cyclase - Tetraodon nigroviridis (Green puffer)
Length = 1128
Score = 52.0 bits (119), Expect = 5e-05
Identities = 23/74 (31%), Positives = 48/74 (64%), Gaps = 2/74 (2%)
Query: 372 SMIEAIQEFD-RERGEG-INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
++++A++ F R R E + +R+G+H+G V G+VG + ++ ++ + V +++MESSG+
Sbjct: 1026 ALLDAVRTFQIRHRPEEQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESSGE 1085
Query: 430 PGRVHISEETSQFL 443
++H+S T L
Sbjct: 1086 ALKIHVSAATGDIL 1099
>UniRef50_Q2L6K5 Cluster: Guanylate cyclase; n=3; Caenorhabditis|Rep:
Guanylate cyclase - Caenorhabditis elegans
Length = 1073
Score = 52.0 bits (119), Expect = 5e-05
Identities = 21/64 (32%), Positives = 39/64 (60%)
Query: 379 EFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEE 438
E R + +R+G+HTGTV G+VG ++ ++ + V A++MES+ +P ++ +S+E
Sbjct: 962 EIPHRRNVKLRIRLGIHTGTVAAGVVGLTAPRYCLFGDTVNVASRMESTSEPEKIQMSQE 1021
Query: 439 TSQF 442
F
Sbjct: 1022 ARDF 1025
>UniRef50_A7RN69 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 769
Score = 52.0 bits (119), Expect = 5e-05
Identities = 20/60 (33%), Positives = 42/60 (70%)
Query: 384 RGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+G+ I +++G+H+G V+ G+VG + ++ ++ N V ++ E++G PG+V+I+E T + L
Sbjct: 615 KGDKIQIKIGIHSGEVVAGVVGHKTPRYCLFGNTVNLTSRTETTGAPGQVNITEFTYRCL 674
>UniRef50_Q9VN32 Cluster: Guanylate cyclase; n=5; Diptera|Rep:
Guanylate cyclase - Drosophila melanogaster (Fruit fly)
Length = 975
Score = 51.6 bits (118), Expect = 7e-05
Identities = 24/68 (35%), Positives = 41/68 (60%), Gaps = 2/68 (2%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLG 444
G + +R+G+HTG G+VG ++ ++ + V A++MES+G R+H+S+ET L
Sbjct: 493 GVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLD 552
Query: 445 --GSYILE 450
G Y +E
Sbjct: 553 ARGGYAIE 560
>UniRef50_Q7YWK7 Cluster: Soluble guanylate cyclase subunit; n=1;
Aplysia californica|Rep: Soluble guanylate cyclase
subunit - Aplysia californica (California sea hare)
Length = 801
Score = 51.6 bits (118), Expect = 7e-05
Identities = 23/58 (39%), Positives = 35/58 (60%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKP 430
M+ A + G I MR+G+HTG VL G+VG + ++ ++ N+V+ ANK ES P
Sbjct: 736 MMAAAENEKSHDGNVIKMRIGIHTGRVLAGVVGRKMPRYCLFGNNVSIANKFESGSVP 793
>UniRef50_UPI0000E47581 Cluster: PREDICTED: similar to natriuretic
peptide receptor A; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to natriuretic
peptide receptor A - Strongylocentrotus purpuratus
Length = 1008
Score = 51.2 bits (117), Expect = 9e-05
Identities = 20/58 (34%), Positives = 40/58 (68%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
E + +RVG+H+G + G+VG + ++ ++ + V A++MES+G+ ++H+SE+T L
Sbjct: 919 EKLKLRVGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMESTGEAMKIHLSEKTKLIL 976
>UniRef50_A2BFQ0 Cluster: Guanylate cyclase; n=3; Danio rerio|Rep:
Guanylate cyclase - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1176
Score = 51.2 bits (117), Expect = 9e-05
Identities = 19/56 (33%), Positives = 39/56 (69%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
+ +R+G+H+G V+ G+VG + ++ ++ + V A++MES+G P R+H+++ T L
Sbjct: 1046 VKIRIGLHSGPVVAGVVGLKMPRYCLFGDTVNTASRMESTGLPYRIHVNQSTVDVL 1101
>UniRef50_Q5DTS7 Cluster: MKIAA4004 protein; n=2; Murinae|Rep:
MKIAA4004 protein - Mus musculus (Mouse)
Length = 422
Score = 51.2 bits (117), Expect = 9e-05
Identities = 36/121 (29%), Positives = 61/121 (50%), Gaps = 12/121 (9%)
Query: 252 LLQLCVHIIGVHIYLMTFVRMRGTFMKVGQSLLVRRQLEMEKQLKEKMIHSVMPPKLASN 311
+L LC +++G + + +R TF + SL RR+L+ EK+ +E ++ S++P LA
Sbjct: 212 VLFLCGNVVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLARE 271
Query: 312 LMNEQVTEADTNVKTYHNPLNSRISNPGSDIKSLFRPFNMSCMDNVSILFADIVGFTRMS 371
+ E + + SR N + F + VS+L+ADIVGFTR++
Sbjct: 272 MKAEIMARLQAGQR-------SRPENTNN-----FHSLYVKRHQGVSVLYADIVGFTRLA 319
Query: 372 S 372
S
Sbjct: 320 S 320
>UniRef50_A6PTF8 Cluster: Putative adenylate/guanylate cyclase; n=1;
Victivallis vadensis ATCC BAA-548|Rep: Putative
adenylate/guanylate cyclase - Victivallis vadensis ATCC
BAA-548
Length = 281
Score = 51.2 bits (117), Expect = 9e-05
Identities = 20/48 (41%), Positives = 35/48 (72%)
Query: 390 MRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISE 437
MR G+H+G+V+ GIVGT ++ +D++ + V A +ME +P R+++SE
Sbjct: 201 MRFGIHSGSVVGGIVGTEKYLYDIFGDTVNTAARMEQLSEPMRINVSE 248
>UniRef50_A6FX69 Cluster: Adenylate or guanylate cyclase; n=1;
Plesiocystis pacifica SIR-1|Rep: Adenylate or guanylate
cyclase - Plesiocystis pacifica SIR-1
Length = 601
Score = 51.2 bits (117), Expect = 9e-05
Identities = 20/60 (33%), Positives = 36/60 (60%)
Query: 389 NMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSYI 448
++RVG+H+G ++ GI+G + +DVW V A +MESS R+++S T + ++
Sbjct: 495 SVRVGLHSGPLIAGIIGRAKLAYDVWGETVNTAARMESSSAADRINVSAPTHAQIAAYFV 554
>UniRef50_A2ECV6 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=1; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1372
Score = 51.2 bits (117), Expect = 9e-05
Identities = 25/67 (37%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Query: 373 MIEAIQEFDRERGEGINMRVGV-HTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPG 431
++++I E + + G + +RVGV G + G++G R+ FDV+ V A MES G+P
Sbjct: 1277 LVDSINEVNAKLGTKLRVRVGVAFGGPISAGLMGIRKPAFDVYGQVVNDAQAMESGGEPM 1336
Query: 432 RVHISEE 438
+VHI++E
Sbjct: 1337 KVHINKE 1343
>UniRef50_P51841 Cluster: Retinal guanylyl cyclase 2 precursor; n=48;
Euteleostomi|Rep: Retinal guanylyl cyclase 2 precursor -
Homo sapiens (Human)
Length = 1108
Score = 51.2 bits (117), Expect = 9e-05
Identities = 25/68 (36%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLGGSY 447
+ +R+G+H+G V+ G+VG ++ ++ + V A++MES+G P R+H+S T L
Sbjct: 977 VRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQN-- 1034
Query: 448 ILEEGEEV 455
L EG EV
Sbjct: 1035 -LSEGYEV 1041
>UniRef50_UPI0000E46159 Cluster: PREDICTED: similar to natriuretic
peptide receptor A; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to natriuretic
peptide receptor A - Strongylocentrotus purpuratus
Length = 853
Score = 50.8 bits (116), Expect = 1e-04
Identities = 22/74 (29%), Positives = 47/74 (63%), Gaps = 2/74 (2%)
Query: 372 SMIEAIQEFD-RER-GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGK 429
S++EA++ F R R E + +R G+H+G + G++G + ++ ++ + V A++MES+G+
Sbjct: 741 SLLEAVKSFKIRHRPDEQLKLRAGIHSGPCVAGVIGLKMPRYCLFGDTVNTASRMESNGE 800
Query: 430 PGRVHISEETSQFL 443
++H S + + L
Sbjct: 801 AMKIHASSDCKEIL 814
>UniRef50_O77149 Cluster: NO-insensitive guanylyl cyclase; n=1;
Manduca sexta|Rep: NO-insensitive guanylyl cyclase -
Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)
Length = 500
Score = 50.8 bits (116), Expect = 1e-04
Identities = 20/59 (33%), Positives = 40/59 (67%)
Query: 385 GEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFL 443
GE + +R+G+HTG + G+VG + ++ ++ + V A++MES G+ ++H+S +T + L
Sbjct: 255 GERLLLRIGMHTGPCVAGVVGLKMPRYCLFGDTVNTASRMESHGEALKIHVSPKTKEVL 313
>UniRef50_A7RUA8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 443
Score = 50.4 bits (115), Expect = 2e-04
Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEETSQFLG--G 445
+ R+ +HTG + GIVG ++ ++D++ V +ES+G P +H+S T + L G
Sbjct: 370 LEFRMAIHTGPCVAGIVGLKKPRYDIFGETVNIVKHLESAGIPQSIHVSSPTCRLLTTLG 429
Query: 446 SYILEEGEEV 455
++LE E+
Sbjct: 430 GFMLETRGEM 439
>UniRef50_A2DJ96 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=3; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1593
Score = 50.4 bits (115), Expect = 2e-04
Identities = 25/84 (29%), Positives = 50/84 (59%), Gaps = 2/84 (2%)
Query: 374 IEAIQEFDRERGEGINMRVGVHT-GTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
+ A+ E + + R+G++T G ++ G++GT + FD+ + + A++++S+G PG
Sbjct: 1470 LTALDEANNMFNSNLMTRIGINTNGPLIAGVLGTDKPVFDIIGDPINVASRLQSTGIPGT 1529
Query: 433 VHISEETSQFL-GGSYILEEGEEV 455
V ISEET + + +Y +E E+
Sbjct: 1530 VQISEETYKLIVNMNYNIERRGEI 1553
>UniRef50_UPI00015B5A8E Cluster: PREDICTED: similar to
ENSANGP00000003998; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000003998 - Nasonia
vitripennis
Length = 643
Score = 50.0 bits (114), Expect = 2e-04
Identities = 23/79 (29%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 373 MIEAIQEFDRERGEGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGR 432
+I ++ G I +R+G+H+G + G+VG + ++ + + V A++M+++ PG+
Sbjct: 512 LISQVRSLVLPSGLEIQIRIGIHSGPAVAGVVGIKVPRYCFFGDTVNTASRMQTTSLPGK 571
Query: 433 VHISEETSQFL-GGSYILE 450
VHIS T L Y++E
Sbjct: 572 VHISPHTRALLPQDRYVIE 590
>UniRef50_Q17010 Cluster: Soluble guanylate cyclase; n=14;
Cellia|Rep: Soluble guanylate cyclase - Anopheles
gambiae (African malaria mosquito)
Length = 111
Score = 50.0 bits (114), Expect = 2e-04
Identities = 18/54 (33%), Positives = 36/54 (66%)
Query: 386 EGINMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISEET 439
E + + +G+H+G V+ G++G R ++ ++ N V ++ E++G PG ++ISE T
Sbjct: 56 EAMKITIGIHSGEVVTGVIGNRMPRYCLFGNTVNLTSRTETTGVPGHINISETT 109
>UniRef50_O02298 Cluster: Soluble guanylate cyclase gcy-35; n=2;
Caenorhabditis|Rep: Soluble guanylate cyclase gcy-35 -
Caenorhabditis elegans
Length = 688
Score = 50.0 bits (114), Expect = 2e-04
Identities = 21/50 (42%), Positives = 35/50 (70%)
Query: 388 INMRVGVHTGTVLCGIVGTRRFKFDVWSNDVTFANKMESSGKPGRVHISE 437
I +R+GVH G V+ G+VG + ++ ++ + V ANKMES+G ++H+SE
Sbjct: 515 IKIRLGVHCGPVVAGVVGIKMPRYCLFGDTVNVANKMESNGIQCKIHVSE 564
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.321 0.135 0.403
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 692,659,762
Number of Sequences: 1657284
Number of extensions: 27617469
Number of successful extensions: 75159
Number of sequences better than 10.0: 414
Number of HSP's better than 10.0 without gapping: 323
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 74177
Number of HSP's gapped (non-prelim): 1014
length of query: 705
length of database: 575,637,011
effective HSP length: 106
effective length of query: 599
effective length of database: 399,964,907
effective search space: 239578979293
effective search space used: 239578979293
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 76 (34.7 bits)
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